Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" AADACL3 ENSG00000188984 "Arylacetamide deacetylase like 3" Q5VUY0 1 12716110-12728760 "Predicted membrane proteins" Hydrolase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "placenta: 1.6;skin 1: 1.2" "Cell type enhanced" "Detected in single" "Extravillous trophoblasts: 1.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" "Cluster 38: Extravillous trophoblasts - Unknown function" "unprognostic (3.01e-1)" "unprognostic (2.54e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ABHD12B "BEM46L3, C14orf29" ENSG00000131969 "Abhydrolase domain containing 12B" Q7Z5M8 14 50872053-50904970 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 6.8;retina: 15.6;skin 1: 10.5" "Cell type enriched" "Detected in some" 7 "Muller glia cells: 188.1" "Cancer enriched" "Detected in many" 5 "testis cancer: 7.6" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "eosinophil: 1.0;neutrophil: 2.1" "Lineage enriched" "Detected in single" 5 "granulocytes: 2.1" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "thalamus: 2.1" "Low region specificity" "Detected in many" HPA002873 Uncertain Uncertain Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 5: Muller glia cells - Visual perception" Nucleoplasm "HPA002873: AB_2220573" "unprognostic (6.61e-2)" "unprognostic (3.49e-2)" "unprognostic (2.92e-3)" "unprognostic (1.99e-3)" "unprognostic (4.63e-2)" "unprognostic (1.17e-2)" "unprognostic (1.62e-2)" "unprognostic (2.09e-1)" "unprognostic (4.31e-2)" "unprognostic (6.27e-2)" "unprognostic (3.30e-1)" "unprognostic (3.35e-1)" "unprognostic (1.70e-3)" "unprognostic (3.16e-2)" "unprognostic (9.62e-2)" "unprognostic (3.18e-3)" "unprognostic (1.68e-1)" 0.5 0.0 2.7 0.1 6.5 1.6 1.3 0.0 2.6 0.0 0.9 0.7 0.0 0.3 0.0 0.2 1.0 0.1 0.1 1.4 1.7 0.2 0.0 0.3 0.1 0.2 5.0 0.0 0.0 0.2 0.1 0.1 1.4 0.0 1.0 15.6 0.0 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.6 6.8 0.3 0.1 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 2.7 6.5 0.0 2.6 1.4 1.7 0.2 5.0 1.4 0.0 6.8 1.0 2.4 0.0 0.0 0.3 0.1 0.4 0.1 1.5 0.0 3.4 0.1 0.1 1.9 0.0 5.0 1.8 2.1 0.1 0.0 2.2 0.0 0.0 7.7 2.5 0.2 0.7 0.0 0.0 9.9 0.0 0.0 0.7 0.0 0.6 1.3 0.0 0.0 0.0 0.1 0.0 0.7 1.0 4.1 0.0 0.0 5.8 1.2 0.1 0.0 0.0 0.0 188.1 0.0 1.0 4.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 26.4 18.1 0.0 0.1 1.2 0.3 0.2 0.0 1.4 0.3 0.1 0.0 1.8 0.2 ABHD8 "FLJ11743, MGC14280, MGC2512" ENSG00000127220 "Abhydrolase domain containing 8" Q96I13 19 17292131-17310236 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 57.8" "Cell type enhanced" "Detected in many" "Early spermatids: 146.2;Horizontal cells: 72.3;Late spermatids: 314.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "PC-3: 53.9;U-266/70: 40.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037658, HPA058209" Approved Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 78: Testis - Spermatogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "Nuclear bodies" "HPA037658: AB_10672602, HPA058209: AB_2683638" "unprognostic (4.71e-3)" "unprognostic (5.06e-2)" "prognostic unfavorable (5.25e-4)" "unprognostic (7.45e-3)" "unprognostic (7.09e-2)" "unprognostic (1.96e-2)" "unprognostic (5.61e-2)" "unprognostic (9.62e-3)" "unprognostic (1.25e-1)" "unprognostic (1.07e-1)" "prognostic favorable (3.04e-5)" "unprognostic (3.77e-1)" "unprognostic (6.36e-3)" "unprognostic (1.56e-1)" "unprognostic (3.14e-1)" "unprognostic (1.50e-1)" "unprognostic (9.24e-2)" 7.4 26.0 32.3 3.9 37.2 4.5 8.8 20.6 57.8 12.0 14.3 16.7 2.7 11.5 1.7 5.7 11.2 2.9 12.4 36.3 23.8 11.6 28.2 9.6 4.5 19.2 26.5 14.2 11.6 8.9 24.6 5.6 19.5 14.6 0.6 6.1 10.5 6.7 13.8 11.3 7.8 2.7 16.1 11.4 11.1 45.7 30.0 4.7 12.1 3.9 2.2 10.2 8.8 27.0 22.5 6.4 3.2 12.6 4.1 1.4 34.2 4.5 6.0 4.8 6.1 5.6 15.0 1.6 6.1 3.5 7.4 3.1 3.2 7.8 1.0 26.6 21.1 7.3 9.6 9.7 13.4 0.5 9.9 3.8 4.7 8.2 1.0 7.4 3.5 12.5 6.6 12.4 1.9 1.2 9.0 1.3 6.0 3.8 53.9 13.3 9.9 6.5 4.3 2.1 3.9 21.3 10.0 3.3 14.6 2.8 13.6 12.6 2.1 4.4 9.6 22.7 8.1 40.6 33.0 7.9 14.9 8.7 4.1 0.0 2.4 3.0 1.1 1.9 0.7 0.3 1.6 0.9 2.9 0.5 1.3 1.2 1.3 1.7 1.9 1.3 1.2 1.0 32.3 37.2 20.6 57.8 36.3 23.8 19.2 26.5 19.5 16.1 30.0 27.0 5.9 0.0 1.3 20.9 5.0 3.8 4.7 8.0 8.6 56.9 9.6 14.4 2.0 7.2 4.8 7.3 18.8 20.6 4.0 0.8 7.9 13.1 146.2 3.0 3.7 4.3 7.2 0.8 22.7 8.5 9.0 7.7 2.6 2.5 4.5 12.3 4.2 13.5 22.5 72.3 19.4 3.3 12.2 8.1 6.9 314.2 12.5 11.1 1.8 8.4 18.4 36.1 7.2 2.5 1.4 8.4 4.3 25.6 9.2 6.3 0.4 9.7 1.7 38.2 6.6 13.6 5.6 64.3 1.5 3.0 4.1 24.8 4.8 10.8 1.3 4.3 AC099489.1 ENSG00000188897 "Novel lipoprotein amino terminal region containing protein" 16 11359845-11527245 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 18.6" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 9.6;Alveolar cells type 2: 5.3;Glandular and luminal cells: 2.3;granulocytes: 3.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 12 "neutrophil: 3.5" "Lineage enriched" "Detected in single" 12 "granulocytes: 3.5" "Cell line enhanced" "Detected in some" "Daudi: 3.1;HDLM-2: 3.4;U-266/70: 1.7" "Not detected" "Not detected" HPA042154 Uncertain NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 64: Macrophages - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 11: Alveolar cells - Smell perception" "HPA042154: AB_2677877" "unprognostic (4.69e-2)" "unprognostic (3.80e-2)" "unprognostic (7.24e-2)" "unprognostic (5.91e-2)" "unprognostic (1.21e-3)" "unprognostic (7.91e-2)" "unprognostic (9.18e-2)" "unprognostic (6.08e-2)" "unprognostic (8.04e-2)" "unprognostic (5.10e-2)" "unprognostic (1.87e-1)" "unprognostic (3.04e-1)" "unprognostic (3.72e-6)" "unprognostic (3.18e-1)" "unprognostic (1.18e-1)" "unprognostic (1.23e-1)" "unprognostic (4.33e-5)" 2.2 0.5 0.7 3.7 0.6 1.5 0.9 0.8 1.7 1.7 0.6 0.8 0.1 0.9 0.3 0.5 3.4 0.5 1.4 0.6 0.4 2.2 2.3 5.2 0.8 0.6 0.5 0.7 0.8 0.5 1.0 0.3 1.0 1.9 0.1 0.2 3.0 0.4 2.4 3.6 1.0 0.1 0.4 18.6 1.2 4.8 0.5 0.2 0.9 0.4 0.3 1.6 1.1 0.9 0.0 0.4 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 3.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.2 0.0 0.2 0.0 0.1 0.0 0.6 0.0 0.8 0.0 0.0 0.0 0.0 0.2 0.2 0.4 0.0 0.1 0.1 1.0 0.3 0.0 0.0 0.2 0.1 1.1 0.0 0.2 0.3 0.2 0.0 0.4 0.4 0.2 0.0 0.1 0.1 0.0 0.0 0.1 0.0 1.7 0.1 0.1 0.0 0.3 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 3.5 0.0 0.0 0.0 0.0 0.0 0.7 0.6 0.8 1.7 0.6 0.4 0.6 0.5 1.0 0.4 0.5 0.9 0.4 9.6 5.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.0 1.5 0.0 0.0 1.3 0.0 0.0 0.1 1.0 0.0 0.0 0.5 0.0 1.6 0.9 0.3 0.0 0.0 0.0 0.2 0.1 0.5 0.0 2.3 3.8 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.3 0.1 0.0 0.0 AC138647.1 ENSG00000226490 "Novel protein" 8 141514638-141518737 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 12 "brain: 4.0;testis: 9.9" "Group enriched" "Detected in some" 5 "Early spermatids: 226.6;Late spermatids: 66.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "cerebral cortex: 1.2;hypothalamus: 4.0;medulla oblongata: 1.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 4.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 9.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 1.2 0.3 4.0 1.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 226.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 66.1 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ACADM "ACAD1, MCAD, MCADH" ENSG00000117054 "Acyl-CoA dehydrogenase medium chain" P11310 1 75724431-75787575 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 367.3;skeletal muscle: 380.0;tongue: 475.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 373.1;Distal tubular cells: 344.4;Hepatocytes: 261.2;Proximal tubular cells: 564.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Daudi: 289.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006198, HPA026542" Enhanced Enhanced Mitochondria NA NA 930000 "Cluster 19: B-cells - Humoral immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA006198: AB_1078087, HPA026542: AB_1844469" "unprognostic (9.04e-3)" "unprognostic (2.36e-1)" "prognostic favorable (7.30e-4)" "unprognostic (5.09e-3)" "unprognostic (1.61e-3)" "unprognostic (5.68e-2)" "unprognostic (6.75e-2)" "unprognostic (1.11e-1)" "unprognostic (8.02e-2)" "unprognostic (4.95e-2)" "unprognostic (9.40e-3)" "unprognostic (3.35e-1)" "prognostic favorable (3.83e-8)" "unprognostic (1.27e-1)" "unprognostic (4.09e-2)" "unprognostic (3.56e-2)" "unprognostic (1.24e-1)" 81.9 82.2 25.2 24.3 25.0 17.3 69.9 26.6 42.2 29.3 30.4 46.8 103.9 20.0 25.3 51.3 30.6 27.8 217.8 24.3 25.9 295.9 367.3 22.6 42.6 26.9 26.8 35.7 35.9 66.3 19.2 16.9 25.8 26.8 49.5 21.2 31.4 26.2 380.0 14.4 75.6 25.5 26.2 27.4 52.8 35.7 25.8 29.7 38.4 475.9 44.3 32.7 21.3 25.2 25.8 20.5 61.0 26.8 53.1 42.1 17.5 48.1 40.4 46.1 38.5 38.3 39.5 289.1 40.7 34.4 39.0 22.8 54.9 41.8 57.8 113.0 25.5 94.4 58.5 58.3 36.4 80.0 23.9 50.7 23.5 39.8 22.8 35.0 36.2 56.6 102.3 60.4 50.5 9.6 96.3 40.6 50.2 80.4 49.5 118.8 83.8 30.6 77.9 70.7 33.8 43.0 38.0 111.6 102.0 43.1 32.7 107.6 20.2 29.9 29.6 26.6 78.1 38.6 62.0 128.1 25.8 67.0 35.3 15.3 14.2 19.3 17.1 20.9 27.3 40.7 17.8 21.5 21.4 24.6 20.3 23.6 0.5 25.0 20.4 23.2 19.5 19.5 25.2 25.0 26.6 42.2 24.3 25.9 26.9 26.8 25.8 26.2 25.8 25.2 42.9 57.7 58.3 29.7 56.5 27.3 41.8 69.0 44.3 39.0 49.0 40.9 373.1 52.9 63.0 58.8 25.0 35.8 39.4 42.6 344.4 37.9 55.4 27.1 32.2 36.2 40.7 67.6 51.6 26.5 19.5 47.6 26.0 25.4 44.9 61.5 43.9 261.2 75.7 30.3 46.7 38.7 63.1 45.6 22.2 24.4 46.9 38.2 51.6 19.7 32.8 53.7 29.9 36.2 36.0 21.2 49.7 45.5 74.9 24.2 88.0 564.8 106.7 30.0 0.0 38.6 43.7 76.3 86.1 46.6 27.0 15.3 39.4 72.5 46.7 35.9 ACAT2 ENSG00000120437 "Acetyl-CoA acetyltransferase 2" Q9BWD1 6 159762045-159779112 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "liver: 231.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 262.1;Early spermatids: 187.0;Exocrine glandular cells: 176.6;Hepatocytes: 214.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB021106, HPA025736, HPA025765, HPA025811" Enhanced Approved Nucleoplasm,Cytosol NA NA 14000000 "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol Nucleoplasm "CAB021106: AB_10058215, HPA025736: AB_1844487, HPA025765: AB_1844485, HPA025811: AB_1844488" "unprognostic (3.31e-1)" "unprognostic (2.44e-2)" "prognostic favorable (1.12e-4)" "prognostic unfavorable (7.25e-4)" "unprognostic (1.38e-1)" "unprognostic (2.03e-1)" "unprognostic (9.25e-2)" "unprognostic (4.76e-2)" "unprognostic (1.43e-1)" "unprognostic (2.58e-1)" "unprognostic (1.21e-1)" "unprognostic (1.59e-1)" "prognostic unfavorable (7.38e-4)" "unprognostic (1.39e-1)" "unprognostic (1.50e-2)" "unprognostic (8.56e-2)" "unprognostic (2.54e-2)" 10.9 21.6 22.2 18.5 24.4 22.4 23.6 30.2 30.0 12.8 20.1 38.5 31.2 10.9 40.0 32.6 11.4 10.6 9.4 22.7 27.6 27.0 231.3 20.2 25.0 39.4 26.3 17.3 9.4 12.5 3.2 11.8 39.1 35.6 33.8 19.5 15.5 9.3 4.9 18.1 17.9 15.8 24.8 9.7 19.5 28.6 24.4 39.4 9.0 7.1 36.7 13.7 9.1 28.1 70.1 58.8 451.9 160.8 57.2 111.6 14.4 57.4 70.5 141.8 244.5 234.0 87.1 55.9 29.0 48.7 458.2 64.5 174.8 465.8 166.7 35.2 174.4 127.4 97.2 418.8 62.0 81.4 35.8 62.2 40.1 231.1 92.9 21.4 68.8 160.1 139.9 104.3 85.5 113.0 137.0 154.0 142.8 65.5 41.7 83.9 94.4 173.1 377.2 93.7 107.8 63.2 67.5 43.3 26.2 18.5 83.4 157.3 39.2 50.3 45.7 72.1 154.0 47.7 89.0 142.0 15.7 151.2 77.1 30.1 24.9 46.7 47.9 33.9 47.3 46.6 54.1 47.8 34.7 51.4 53.3 43.2 11.0 41.3 23.6 30.4 79.0 46.2 22.2 24.4 30.2 30.0 22.7 27.6 39.4 26.3 39.1 24.8 24.4 28.1 11.8 12.8 45.4 15.3 25.8 26.1 32.4 262.1 22.2 19.4 33.4 24.5 1.2 42.9 115.5 20.2 2.1 53.7 28.6 34.7 70.5 78.8 187.0 14.3 9.9 18.8 17.2 38.5 14.3 176.6 97.0 21.6 9.7 25.9 13.3 47.7 16.1 214.8 58.1 13.5 14.7 23.6 83.4 14.8 29.8 128.8 13.7 25.7 30.2 1.0 58.9 22.5 30.9 13.0 17.5 65.6 28.8 19.2 25.5 38.7 15.4 50.0 30.1 24.7 0.0 25.1 44.9 28.5 45.6 43.0 21.0 35.2 31.0 102.5 33.0 38.9 ACOT1 "ACH2, CTE-1, LACH2" ENSG00000184227 "Acyl-CoA thioesterase 1" Q86TX2 14 73537143-73543796 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 44.4" "Cell type enhanced" "Detected in some" "Astrocytes: 10.7;Cardiomyocytes: 51.5;Excitatory neurons: 13.8;Inhibitory neurons: 12.0;Oligodendrocyte precursor cells: 8.5;Oligodendrocytes: 15.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Hep G2: 30.5;T-47d: 49.8" HPA043705 Approved Approved Mitochondria NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA043705: AB_2678626" "unprognostic (4.74e-3)" "unprognostic (3.81e-3)" "unprognostic (7.65e-2)" "unprognostic (8.66e-2)" "unprognostic (1.22e-1)" "unprognostic (1.29e-1)" "unprognostic (4.54e-2)" "unprognostic (1.29e-2)" "unprognostic (1.53e-1)" "unprognostic (1.73e-2)" "unprognostic (1.84e-1)" "unprognostic (4.16e-1)" "prognostic favorable (5.09e-8)" "unprognostic (1.35e-3)" "unprognostic (4.60e-2)" "unprognostic (1.75e-1)" "unprognostic (1.43e-1)" 15.1 12.9 10.4 3.6 10.2 2.4 13.0 9.3 11.3 5.7 8.4 12.9 10.8 13.2 11.6 3.4 7.3 3.5 18.6 10.1 9.7 25.9 44.4 7.3 2.3 9.2 10.1 3.5 3.0 2.2 2.0 2.9 9.6 5.6 5.4 2.9 5.1 9.3 19.6 8.9 11.8 20.9 9.5 2.6 6.4 4.2 11.1 2.5 3.6 29.3 2.1 9.5 4.0 9.6 10.7 9.0 3.3 0.7 15.2 9.1 0.1 2.9 8.5 7.0 12.6 3.9 6.9 0.0 0.4 5.8 0.9 6.0 0.0 1.4 3.4 4.5 2.8 4.6 2.8 30.5 14.4 0.1 5.1 12.0 0.6 5.6 0.0 0.7 3.2 0.0 0.0 0.0 5.5 4.7 0.6 1.0 3.4 1.4 4.9 9.5 6.8 0.2 6.9 8.7 4.9 6.4 9.0 20.2 12.2 0.9 49.8 9.9 4.2 5.2 7.5 4.2 0.7 0.1 0.0 2.6 6.2 0.0 6.8 0.7 0.9 0.7 4.1 1.1 3.5 2.6 3.9 3.4 3.8 1.9 3.5 3.9 0.1 3.5 1.1 2.2 5.1 2.6 10.4 10.2 9.3 11.3 10.1 9.7 9.2 10.1 9.6 9.5 11.1 9.6 0.2 0.0 3.2 10.7 0.0 0.0 0.1 0.6 1.8 0.0 0.4 0.4 51.5 0.0 0.4 0.0 0.0 0.7 1.3 0.2 0.0 0.4 0.6 0.3 0.3 0.7 0.0 2.7 13.8 8.0 0.3 2.6 0.0 0.3 0.0 0.1 0.0 1.1 0.9 0.0 12.0 0.0 2.0 0.3 0.0 0.0 0.0 0.5 1.8 3.7 0.0 0.0 0.0 8.5 15.1 2.6 0.0 0.4 0.3 0.0 0.0 3.7 0.3 0.0 0.0 0.0 3.6 0.1 0.2 0.6 0.0 0.8 0.2 0.0 0.2 0.0 ACOT4 "FLJ31235, PTE-Ib, PTE2B" ENSG00000177465 "Acyl-CoA thioesterase 4" Q8N9L9 14 73591873-73595766 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 15.0;liver: 16.8" "Cell type enhanced" "Detected in many" "Hepatocytes: 26.4;Proximal tubular cells: 59.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 17.6;MCF7: 14.1;SK-BR-3: 27.9;T-47d: 69.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA000779 Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 6: T47d - Mammary gland" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA000779: AB_1078093" "unprognostic (2.29e-3)" "unprognostic (2.53e-3)" "unprognostic (2.30e-1)" "unprognostic (2.29e-3)" "unprognostic (1.16e-1)" "unprognostic (2.11e-1)" "unprognostic (2.25e-2)" "unprognostic (3.10e-2)" "unprognostic (1.72e-2)" "unprognostic (9.56e-2)" "prognostic unfavorable (1.77e-4)" "unprognostic (3.95e-1)" "prognostic favorable (8.43e-5)" "unprognostic (2.47e-1)" "unprognostic (1.92e-1)" "unprognostic (7.31e-2)" "unprognostic (1.73e-1)" 4.9 1.4 3.7 1.1 3.7 0.6 4.6 4.2 4.3 3.9 2.4 3.0 4.3 0.8 2.6 1.5 0.9 0.9 0.9 3.6 2.9 15.0 16.8 3.6 1.3 3.1 2.7 0.9 1.5 1.0 0.4 1.8 3.3 1.4 3.4 0.8 1.7 1.8 0.6 0.6 3.3 1.5 2.5 1.5 2.0 2.2 2.9 1.0 1.3 0.6 1.3 1.2 0.9 3.2 10.7 2.9 0.3 0.1 1.3 0.6 0.0 0.6 0.0 0.7 1.2 0.3 17.6 0.0 0.6 1.0 0.0 1.1 0.0 0.1 0.1 5.8 0.1 0.0 3.5 0.0 2.0 0.0 9.5 0.8 1.3 0.3 0.0 0.1 0.2 0.0 0.0 0.0 0.6 14.1 0.3 1.9 0.9 3.7 2.8 0.0 0.0 0.0 0.4 5.2 1.5 0.3 6.9 27.9 2.1 0.1 69.7 10.5 0.2 0.0 6.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 11.5 0.0 1.4 14.7 0.6 7.3 2.1 6.9 8.4 0.4 3.3 4.0 8.5 0.0 7.2 0.2 0.9 7.2 5.3 3.7 3.7 4.2 4.3 3.6 2.9 3.1 2.7 3.3 2.5 2.9 3.2 0.4 0.0 2.7 1.0 1.0 0.3 1.1 3.8 1.2 0.2 5.5 4.2 1.7 7.2 2.8 11.0 0.0 15.9 3.6 8.3 15.6 4.2 1.8 4.1 1.1 0.5 0.0 0.0 1.4 9.2 13.8 1.5 3.1 5.6 5.7 4.1 0.0 26.4 11.2 1.7 0.8 3.2 8.2 3.0 0.3 5.3 0.3 2.1 0.0 1.9 1.0 0.7 11.3 0.5 0.3 6.2 2.6 0.4 1.5 1.1 15.7 59.8 2.9 0.5 0.0 1.5 1.1 3.2 15.8 2.6 0.3 4.5 5.1 0.4 2.6 1.3 ACSBG1 "BG1, BGM, FLJ30320, hBG1, hsBG, KIAA0631, MGC14352" ENSG00000103740 "Acyl-CoA synthetase bubblegum family member 1" Q96GR2 15 78167468-78245688 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 56.6;skin 1: 14.3" "Cell type enriched" "Detected in some" 5 "Astrocytes: 158.0" "Cancer enriched" "Detected in some" 4 "glioma: 3.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "NTERA-2: 3.1;SK-MEL-30: 1.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041642, CAB045955, HPA058869" Approved Approved Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 70: Brain - Nervous system development" "Cluster 5: NTERA-2 - Transcription" "Cluster 64: Astrocytes - Nervous system maintenance" Vesicles "CAB045955: AB_11124196, HPA041642: AB_2677593, HPA058869: AB_2683840" "unprognostic (1.28e-1)" "unprognostic (1.63e-2)" "unprognostic (1.29e-2)" "unprognostic (2.28e-1)" "unprognostic (2.29e-2)" "unprognostic (4.18e-2)" "unprognostic (1.32e-2)" "unprognostic (1.58e-2)" "unprognostic (1.86e-1)" "unprognostic (5.64e-2)" "unprognostic (2.02e-1)" "unprognostic (4.13e-1)" "unprognostic (1.05e-1)" "unprognostic (1.40e-1)" "unprognostic (2.96e-1)" "unprognostic (4.19e-2)" "unprognostic (1.42e-2)" 0.1 5.5 23.0 0.4 42.6 2.4 1.6 30.5 24.0 0.5 0.0 1.1 0.4 0.2 0.7 0.3 2.8 0.2 0.8 19.6 35.9 0.5 0.4 0.5 0.4 46.0 39.9 0.3 0.2 0.0 0.5 0.1 47.7 0.8 0.1 0.6 0.3 0.2 0.2 14.3 0.5 0.2 45.8 0.3 0.3 3.7 36.6 3.4 0.2 0.0 0.1 0.3 0.5 56.6 0.3 0.0 0.6 0.9 0.0 0.0 0.2 0.2 0.0 0.2 0.0 0.2 0.2 0.3 0.0 0.0 0.2 0.3 0.0 0.1 0.0 0.1 0.5 0.3 0.6 0.3 0.0 0.2 0.6 0.2 0.0 0.1 0.1 0.2 0.0 0.4 0.2 0.4 0.0 0.1 0.2 0.5 3.1 0.2 0.1 0.1 0.4 0.2 0.0 0.4 0.2 0.3 0.1 0.4 1.5 0.3 0.1 0.2 0.4 0.2 0.2 0.1 0.1 0.3 0.1 0.3 0.1 0.2 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 1.0 0.0 0.3 23.0 42.6 30.5 24.0 19.6 35.9 46.0 39.9 47.7 45.8 36.6 56.6 0.1 0.0 2.0 158.0 0.6 1.1 0.6 0.3 0.6 1.9 0.2 0.1 3.0 0.0 2.7 0.0 4.2 0.2 0.5 0.3 0.0 0.0 1.8 4.4 0.3 0.2 0.0 4.6 0.7 0.0 0.2 0.7 0.5 0.3 0.0 0.1 0.0 0.0 0.1 0.0 1.0 0.2 0.0 0.0 0.0 1.7 0.3 4.0 1.8 2.8 0.1 0.2 1.0 7.5 26.9 0.2 0.0 0.0 0.9 0.3 0.1 0.2 19.1 3.3 0.0 0.3 1.0 2.0 10.0 0.4 0.6 0.4 0.5 1.6 0.1 0.7 ACSM6 "bA310E22.3, C10orf129" ENSG00000173124 "Acyl-CoA synthetase medium chain family member 6" Q6P461 10 95194200-95228928 "Enzymes, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "lymphoid tissue: 3.6;pancreas: 4.0;skin 1: 1.9;stomach 1: 1.9;urinary bladder: 1.0" "Cell type enhanced" "Detected in some" "Astrocytes: 2.0;Cone photoreceptor cells: 2.1;Early spermatids: 2.4;Excitatory neurons: 3.8;Inhibitory neurons: 3.4;Oligodendrocytes: 2.1;Rod photoreceptor cells: 5.3" "Cancer enriched" "Detected in single" 7 "urothelial cancer: 1.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 30 "RT4: 3.7" HPA044593 Uncertain NA NA "Cluster 25: Pancreas - Digestion" "Cluster 15: RT4 - Unknown function" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA044593: AB_10960261" "unprognostic (2.91e-2)" "unprognostic (2.87e-1)" "unprognostic (3.64e-2)" "unprognostic (5.73e-2)" "unprognostic (2.48e-2)" "unprognostic (6.34e-2)" "unprognostic (1.41e-2)" "unprognostic (1.91e-1)" "unprognostic (3.75e-3)" "unprognostic (2.25e-1)" "unprognostic (2.37e-1)" "unprognostic (1.11e-1)" "prognostic favorable (7.71e-4)" 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 1.9 0.1 0.1 3.6 0.4 0.0 0.0 1.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.4 0.0 0.0 2.0 0.2 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 2.4 0.6 1.2 0.6 0.0 0.0 3.8 0.0 0.0 0.1 1.1 1.1 0.0 0.0 0.0 0.0 0.1 0.0 3.4 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 2.1 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 5.3 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 ACSS2 "ACAS2, AceCS, ACS, ACSA, dJ1161H23.1" ENSG00000131069 "Acyl-CoA synthetase short chain family member 2" Q9NR19 20 34872146-34927962 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 117.3" "Cell type enhanced" "Detected in all" "Distal enterocytes: 137.7;Hepatocytes: 138.9;Intestinal goblet cells: 100.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 34.3" "Group enriched" "Detected in many" 5 "dendritic cells: 22.6;granulocytes: 34.3;monocytes: 21.8" "Cell line enhanced" "Detected in many" "HBEC3-KT: 132.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004141 Approved NA NA 16000 "Cluster 38: Basophils - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA004141: AB_1078094" "unprognostic (1.97e-2)" "unprognostic (1.33e-1)" "unprognostic (1.70e-1)" "unprognostic (2.25e-2)" "unprognostic (1.84e-2)" "unprognostic (1.86e-1)" "unprognostic (1.42e-1)" "unprognostic (5.45e-2)" "unprognostic (1.13e-1)" "unprognostic (3.92e-2)" "unprognostic (1.66e-1)" "unprognostic (1.42e-2)" "prognostic favorable (2.04e-4)" "unprognostic (2.72e-1)" "unprognostic (2.32e-1)" "unprognostic (3.08e-1)" "unprognostic (2.54e-1)" 69.3 23.7 4.0 10.7 9.3 7.5 27.2 6.8 7.8 15.1 6.0 54.6 64.2 13.7 34.3 18.6 22.1 10.7 49.8 3.3 6.4 22.0 46.9 23.2 4.0 12.1 5.9 13.0 14.8 19.6 3.8 17.2 12.7 12.2 32.9 5.3 38.1 16.2 117.3 17.1 46.8 11.3 5.1 8.1 37.7 10.6 7.2 4.0 9.6 99.2 7.0 9.3 11.9 16.3 32.8 11.6 17.1 10.7 69.5 59.1 25.5 14.5 32.4 13.9 21.7 27.3 40.6 0.1 18.6 24.1 50.2 26.0 20.1 132.4 9.5 0.1 7.1 37.2 6.6 18.5 46.2 6.6 28.1 50.3 34.2 24.8 34.5 27.8 27.7 4.2 22.0 7.1 15.8 13.3 2.4 18.8 3.3 27.6 44.1 15.9 20.3 83.4 62.5 9.0 2.9 14.5 24.7 49.1 32.1 21.2 19.6 24.4 23.5 12.3 7.8 12.4 7.9 24.0 19.7 9.1 32.3 9.3 9.1 34.3 21.8 6.6 1.2 13.3 1.2 0.7 3.0 1.3 22.6 1.1 5.3 2.9 12.2 0.7 6.4 4.2 2.0 9.2 4.0 9.3 6.8 7.8 3.3 6.4 12.1 5.9 12.7 5.1 7.2 16.3 8.8 12.8 41.1 17.6 4.2 7.8 9.4 13.5 10.2 6.4 27.6 10.9 82.2 20.0 16.6 11.0 6.2 15.5 3.7 137.7 11.7 20.8 9.0 8.0 8.2 13.5 7.8 29.0 18.5 33.7 11.2 11.4 58.1 13.0 9.5 35.3 13.6 138.9 16.4 8.4 18.2 100.6 18.3 17.9 13.9 7.2 11.5 15.6 14.2 17.8 19.4 9.1 1.0 5.5 86.5 23.4 66.4 4.5 14.6 11.2 70.4 60.5 7.6 4.1 13.1 7.2 9.8 32.1 20.3 12.3 10.9 20.9 5.1 7.8 75.1 13.0 ACTG2 "ACTA3, ACTL3, ACTSG" ENSG00000163017 "Actin gamma 2, smooth muscle" P63267 2 73892314-73919865 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Muscle protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 8846.3;seminal vesicle: 6238.4;smooth muscle: 8607.9" "Group enriched" "Detected in many" 4 "Breast myoepithelial cells: 394.2;Smooth muscle cells: 287.8" "Cancer enhanced" "Detected in all" "prostate cancer: 255.0;stomach cancer: 237.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 11 "T-reg: 8.6" "Lineage enriched" "Detected in single" 17 "T-cells: 8.6" "Cell line enhanced" "Detected in many" "BEWO: 63.8;BJ hTERT+: 53.5;BJ hTERT+ SV40 Large T+: 214.8;HHSteC: 55.1;SuSa: 52.5;U-251 MG: 229.9" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 4 "midbrain: 11.8;spinal cord: 4.7" "HPA041264, HPA041271" Supported NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 48: Smooth muscle cells - ECM organization" "HPA041264: AB_2677383, HPA041271: AB_2677386" "unprognostic (5.79e-3)" "unprognostic (2.25e-1)" "unprognostic (2.36e-2)" "unprognostic (2.91e-1)" "unprognostic (4.56e-3)" "unprognostic (2.50e-1)" "unprognostic (8.05e-2)" "unprognostic (6.53e-2)" "unprognostic (4.48e-2)" "unprognostic (2.93e-1)" "unprognostic (7.23e-2)" "unprognostic (4.75e-2)" "prognostic unfavorable (3.95e-7)" "unprognostic (9.30e-3)" "unprognostic (6.84e-2)" "unprognostic (2.29e-2)" "unprognostic (7.57e-3)" 189.6 37.1 2.8 724.8 3.9 0.0 138.2 2.8 10.0 494.7 4.8 8846.3 392.1 3622.6 124.6 1954.7 857.3 330.4 30.4 2.9 2.9 11.3 10.8 137.5 6.8 3.4 3.1 88.5 8.1 0.9 6.1 96.4 3.1 2250.2 1179.0 0.0 75.1 6238.4 16.3 91.8 1353.8 8607.9 2.9 16.6 2099.7 4.8 3.1 2.8 33.8 6.9 1.2 2914.5 667.3 2.8 0.7 0.3 20.5 0.3 0.0 0.0 63.8 13.5 53.5 214.8 38.6 6.7 0.0 0.3 0.9 0.0 0.4 0.1 36.9 0.0 28.3 0.1 0.0 0.0 2.9 0.5 55.1 0.2 0.6 0.5 0.3 29.0 0.0 1.5 0.0 0.2 0.0 0.0 0.5 0.0 2.9 7.9 0.2 0.0 0.1 0.2 0.4 3.1 0.5 13.6 0.6 2.3 0.3 2.8 1.2 52.5 0.0 0.3 0.0 1.1 2.3 2.5 229.9 0.1 0.3 0.8 0.7 1.0 0.9 0.2 0.5 0.3 0.2 0.3 0.1 0.1 0.8 0.3 0.4 0.1 0.4 0.5 0.1 0.2 0.4 0.1 8.6 2.4 2.8 3.9 2.8 10.0 2.9 2.9 3.4 3.1 3.1 2.9 3.1 2.8 3.5 0.0 0.5 0.0 0.4 4.5 2.7 0.5 0.6 0.0 9.8 394.2 14.6 0.0 0.1 0.0 0.0 7.4 0.7 0.0 0.0 0.0 5.8 2.8 1.5 3.1 0.0 0.0 0.1 0.0 36.8 74.1 0.0 4.8 0.0 1.0 22.9 0.3 5.4 0.0 0.1 0.0 0.0 0.0 10.4 26.6 0.3 1.0 7.2 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.1 0.0 10.8 0.0 0.4 0.8 0.0 6.6 1.8 287.8 0.2 3.2 0.4 7.7 6.4 1.7 8.4 0.0 3.7 ACVR1B "ActRIB, ACVRLK4, ALK4, SKR2" ENSG00000135503 "Activin A receptor type 1B" P36896 12 51951699-51997078 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 3.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026126, HPA063761" Approved Approved Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "CAB026126: , HPA063761: AB_2685115" "unprognostic (8.66e-2)" "unprognostic (5.72e-2)" "unprognostic (1.16e-1)" "unprognostic (3.23e-3)" "unprognostic (2.34e-1)" "unprognostic (2.54e-1)" "unprognostic (1.21e-3)" "unprognostic (1.00e-1)" "unprognostic (7.68e-2)" "unprognostic (5.29e-2)" "unprognostic (2.56e-1)" "unprognostic (2.37e-1)" "unprognostic (4.52e-2)" "unprognostic (9.02e-2)" "unprognostic (6.60e-2)" "unprognostic (8.96e-2)" "unprognostic (4.79e-2)" 16.5 10.3 20.7 10.0 20.8 13.5 13.2 13.6 23.4 13.9 9.1 24.6 28.2 8.8 18.0 20.9 15.3 12.2 10.1 21.5 13.3 34.3 29.9 14.7 6.4 12.5 13.9 9.4 40.7 52.7 14.7 11.1 13.1 14.0 24.4 17.4 32.8 15.3 13.1 45.6 26.1 8.1 9.5 8.8 24.9 15.7 16.1 7.6 11.4 8.8 7.4 12.6 18.8 18.3 11.4 24.3 18.6 10.3 20.9 16.2 10.5 12.6 14.2 13.1 9.9 49.5 17.1 5.0 17.2 13.8 14.6 19.6 17.8 15.2 13.5 7.3 21.0 12.3 5.9 15.6 23.8 19.9 43.8 32.0 19.4 14.8 18.6 13.9 18.7 17.7 13.3 14.9 11.8 23.2 19.1 17.2 18.0 24.0 8.5 10.2 14.4 6.4 37.2 17.0 23.5 19.5 13.6 19.2 9.0 13.1 21.1 12.8 12.0 9.0 13.6 10.2 6.1 9.0 6.8 6.7 9.7 9.4 11.8 2.5 1.2 3.9 0.3 1.8 0.5 0.0 0.3 0.3 0.7 0.2 0.8 0.4 1.0 0.0 2.2 0.3 0.5 0.3 20.7 20.8 13.6 23.4 21.5 13.3 12.5 13.9 13.1 9.5 16.1 18.3 8.0 3.2 13.4 8.1 2.9 18.6 10.1 9.2 23.3 45.3 11.3 8.6 5.9 17.2 12.0 25.8 29.2 0.7 2.0 49.7 3.9 17.7 2.9 12.3 8.1 10.9 24.6 0.8 34.8 14.4 0.8 12.6 19.9 9.0 11.4 9.4 17.9 24.4 4.0 37.0 30.2 28.7 2.0 16.7 5.3 8.4 9.9 10.0 7.2 9.4 10.1 8.8 1.0 21.6 11.3 13.3 22.1 9.4 2.3 15.1 31.8 17.0 15.8 24.5 6.6 17.5 12.2 3.8 16.5 17.7 25.3 0.5 4.6 5.6 24.7 15.5 ADGRL4 "ELTD1, ETL" ENSG00000162618 "Adhesion G protein-coupled receptor L4" Q9HBW9 1 78889764-79282124 "G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 73.1" "Group enriched" "Detected in many" 5 "Adipocytes: 559.9;Endothelial cells: 276.0;Hepatic stellate cells: 287.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "hTERT-RPE1: 101.2;HUVEC TERT2: 330.0;TIME: 379.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA025229 Supported NA NA 3800000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA025229: AB_10602493" "unprognostic (2.67e-1)" "unprognostic (2.17e-1)" "unprognostic (2.05e-2)" "unprognostic (2.58e-1)" "unprognostic (5.32e-2)" "unprognostic (8.11e-3)" "unprognostic (2.01e-1)" "unprognostic (1.23e-1)" "unprognostic (7.52e-2)" "unprognostic (2.38e-1)" "unprognostic (2.57e-1)" "unprognostic (1.52e-1)" "prognostic unfavorable (1.60e-4)" "unprognostic (5.32e-3)" "unprognostic (1.48e-1)" "unprognostic (3.45e-2)" "unprognostic (3.85e-3)" 73.1 8.2 7.7 9.7 8.2 0.7 64.0 8.5 13.8 22.1 7.0 9.3 4.7 16.3 6.2 9.0 12.1 22.4 24.2 8.0 8.0 15.2 14.3 18.0 9.9 9.1 7.7 4.8 4.7 9.7 5.1 22.5 9.1 9.4 6.3 3.0 7.9 8.9 14.2 9.0 8.6 27.6 7.6 39.8 8.0 6.7 9.8 4.6 20.8 23.6 7.1 24.0 10.4 8.4 0.0 0.0 25.7 0.2 7.3 24.7 0.0 7.8 7.7 0.5 0.3 0.8 0.2 0.2 0.6 22.5 0.0 0.0 0.1 0.0 5.0 0.0 0.0 0.5 0.7 0.1 25.3 0.0 0.3 17.8 0.4 55.7 0.3 101.2 330.0 0.2 0.4 2.5 7.0 0.0 0.0 1.0 0.4 0.2 0.4 0.2 0.0 0.0 61.1 3.1 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 379.3 0.2 5.8 2.0 0.0 0.8 0.5 0.1 0.3 0.5 26.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 7.7 8.2 8.5 13.8 8.0 8.0 9.1 7.7 9.1 7.6 9.8 8.4 559.9 0.0 6.0 0.3 1.2 0.0 0.4 0.0 4.6 0.0 1.8 2.5 7.6 5.7 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.2 45.3 0.8 1.5 276.0 0.0 2.7 1.5 0.2 0.0 10.2 0.0 3.8 0.0 0.0 287.7 3.5 0.6 1.7 1.0 0.0 0.0 19.2 0.0 57.9 0.6 1.5 0.0 72.1 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.4 1.2 1.3 0.0 0.0 0.0 0.4 0.0 5.1 5.7 7.2 1.8 1.0 0.0 0.0 1.1 5.4 0.0 0.7 ADORA1 RDC7 ENSG00000163485 "Adenosine A1 receptor" P30542 1 203090654-203167405 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 54.8;testis: 21.4" "Cell type enhanced" "Detected in some" "Excitatory neurons: 18.1;granulocytes: 22.3;Muller glia cells: 44.4;Oligodendrocyte precursor cells: 35.2;Oligodendrocytes: 31.5" "Cancer enhanced" "Detected in many" "glioma: 24.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 40.3;MCF7: 24.4;RH-30: 65.4;RPTEC TERT1: 31.7;SK-BR-3: 35.2;U-138 MG: 20.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044383 Supported "Plasma membrane" NA NA "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 5: Muller glia cells - Visual perception" "Plasma membrane" "HPA044383: AB_2678921" "unprognostic (3.93e-3)" "unprognostic (8.16e-2)" "unprognostic (6.16e-2)" "unprognostic (2.38e-3)" "unprognostic (2.25e-2)" "unprognostic (2.34e-1)" "unprognostic (4.64e-2)" "unprognostic (4.17e-2)" "unprognostic (3.04e-1)" "unprognostic (4.80e-3)" "unprognostic (1.42e-1)" "unprognostic (2.98e-1)" "unprognostic (2.96e-3)" "unprognostic (1.54e-1)" "unprognostic (1.27e-1)" "unprognostic (4.13e-2)" "unprognostic (5.76e-4)" 3.7 0.2 31.9 1.6 34.6 0.0 4.6 28.6 33.8 1.0 0.0 1.0 1.0 1.2 0.6 1.1 1.2 0.9 11.4 29.6 23.0 9.3 0.4 1.7 0.6 35.7 35.0 0.3 13.2 8.0 1.9 6.8 41.8 1.0 0.6 4.8 6.4 0.4 1.7 4.6 1.2 0.4 23.6 6.3 1.0 21.4 54.8 0.4 2.2 2.5 0.5 1.6 0.7 41.5 0.3 3.0 0.6 0.2 0.2 1.6 0.2 2.0 3.0 0.7 0.4 40.3 0.7 0.0 8.9 7.3 4.8 0.1 0.7 0.0 0.2 0.0 1.1 0.0 0.4 0.0 0.6 0.0 0.1 0.9 0.0 0.9 0.0 6.4 0.0 6.4 0.0 0.1 6.2 24.4 0.1 0.0 10.2 0.0 0.0 0.0 65.4 2.3 31.7 0.0 0.8 0.7 4.4 35.2 0.5 3.6 2.0 1.0 0.0 20.9 10.6 0.0 11.7 0.0 0.2 0.0 10.5 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.9 34.6 28.6 33.8 29.6 23.0 35.7 35.0 41.8 23.6 54.8 41.5 0.0 0.0 0.0 11.1 0.0 0.0 0.0 0.0 0.0 1.1 9.4 6.9 3.1 7.2 0.0 3.7 0.0 0.1 0.1 0.1 0.0 11.7 0.1 0.0 0.4 0.3 0.0 0.0 18.1 3.3 1.3 1.1 0.0 0.1 22.3 0.8 0.0 0.0 0.9 0.0 2.9 0.0 0.0 1.0 1.0 0.5 0.0 0.6 1.8 1.9 0.2 44.4 0.0 35.2 31.5 0.5 0.0 0.7 0.0 0.0 0.0 3.0 0.0 1.6 0.0 0.0 0.6 0.1 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.1 ADORA2B ENSG00000170425 "Adenosine A2b receptor" P29275 17 15944917-15975746 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.7;urinary bladder: 14.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 73.5;Basal respiratory cells: 75.6;Langerhans cells: 31.9;Suprabasal keratinocytes: 64.4;Urothelial cells: 32.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 14.9;myeloid DC: 9.0" "Group enriched" "Detected in many" 97 "dendritic cells: 9.0;granulocytes: 14.9;monocytes: 5.0" "Cell line enhanced" "Detected in many" "GAMG: 160.8;HMC-1: 162.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073747 Uncertain Cytosol NA Yes "Cluster 10: Basophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "HPA073747: " "unprognostic (6.04e-3)" "unprognostic (1.22e-1)" "unprognostic (8.14e-2)" "unprognostic (1.32e-2)" "unprognostic (4.68e-1)" "unprognostic (7.88e-3)" "unprognostic (2.64e-4)" "unprognostic (1.44e-1)" "unprognostic (1.84e-1)" "unprognostic (1.50e-2)" "unprognostic (2.18e-3)" "unprognostic (1.38e-1)" "unprognostic (1.66e-9)" "unprognostic (2.07e-1)" "unprognostic (3.49e-1)" "unprognostic (1.50e-2)" "unprognostic (2.84e-1)" 0.5 1.1 7.5 1.7 9.4 0.8 0.7 7.0 11.7 2.4 9.0 8.6 0.2 0.7 0.5 9.1 0.9 1.1 1.6 9.1 7.3 0.3 0.1 1.9 0.3 7.7 7.7 0.0 1.3 0.0 1.4 5.0 7.1 1.3 6.6 2.8 1.4 0.1 0.1 8.5 1.3 1.3 6.4 0.2 1.2 0.3 8.3 0.4 0.1 0.5 1.3 14.2 5.2 8.2 34.1 18.3 0.6 0.7 5.8 11.1 0.7 6.4 28.4 18.3 22.6 8.8 34.6 4.4 7.8 5.7 160.8 51.9 7.9 47.8 24.2 9.7 18.0 32.7 5.8 13.0 22.3 0.0 162.6 6.5 20.1 26.0 60.4 31.3 9.3 5.1 1.6 0.1 18.2 8.9 2.2 6.6 1.9 72.0 25.5 0.1 0.4 0.0 19.1 9.1 0.8 1.2 14.3 3.4 9.0 13.4 0.1 5.1 7.7 6.5 17.1 18.3 30.3 2.8 0.0 0.0 25.8 0.0 9.2 14.9 4.2 2.8 0.0 5.0 0.0 0.0 0.0 0.0 9.0 0.0 0.0 0.0 0.4 0.0 2.6 0.1 0.0 1.7 7.5 9.4 7.0 11.7 9.1 7.3 7.7 7.7 7.1 6.4 8.3 8.2 0.1 3.2 4.2 18.9 0.2 73.5 21.0 75.6 27.3 0.2 1.3 1.9 0.9 1.5 20.2 0.0 0.0 10.9 0.1 10.8 0.0 6.6 0.9 0.9 0.6 1.7 2.4 3.4 0.9 0.9 3.2 4.9 2.0 1.2 0.0 0.1 2.2 0.0 4.5 0.0 1.1 1.7 2.0 1.4 31.9 0.4 0.0 6.7 7.2 3.7 1.3 7.9 0.0 1.0 1.0 1.0 7.2 0.0 0.0 15.6 0.2 0.0 8.3 0.5 0.0 0.7 2.1 0.5 1.4 23.0 64.4 6.2 0.3 0.3 5.7 32.4 AGPAT3 "LPAAT-gamma, LPAAT3" ENSG00000160216 "1-acylglycerol-3-phosphate O-acyltransferase 3" Q9NRZ7 21 43865223-43987592 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 183.5;Early spermatids: 219.0;Late spermatids: 219.3;Rod photoreceptor cells: 184.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 9.6" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 54: Non-specific - Microtubule organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "unprognostic (2.36e-2)" "prognostic unfavorable (8.31e-4)" "unprognostic (5.50e-2)" "unprognostic (4.56e-3)" "unprognostic (4.70e-2)" "unprognostic (8.55e-2)" "unprognostic (4.88e-2)" "unprognostic (9.72e-3)" "unprognostic (2.14e-1)" "unprognostic (3.54e-2)" "unprognostic (1.65e-1)" "unprognostic (2.84e-1)" "prognostic favorable (2.29e-4)" "unprognostic (1.50e-2)" "unprognostic (8.91e-2)" "unprognostic (1.80e-1)" "unprognostic (4.60e-2)" 20.9 20.9 41.5 19.2 47.1 11.1 15.1 42.3 34.9 11.7 14.8 22.0 44.7 10.3 12.6 25.7 12.3 13.8 27.8 38.4 36.0 53.4 53.2 18.8 16.4 52.1 41.8 10.4 21.3 24.6 14.7 12.2 39.2 13.8 11.9 61.9 30.5 11.6 62.3 24.3 52.4 8.7 47.8 19.1 18.0 26.4 48.1 15.4 21.4 50.2 10.3 15.4 15.0 48.2 73.0 40.0 10.0 27.5 17.8 20.4 7.7 32.6 40.6 40.8 25.1 40.3 51.4 24.5 24.3 39.3 38.4 27.8 17.3 36.5 11.8 117.2 45.8 10.8 24.4 54.8 33.6 39.6 23.5 25.1 30.4 36.1 15.0 35.1 31.2 8.0 61.4 39.1 15.0 31.2 0.4 22.9 4.7 28.2 28.5 40.6 11.3 65.9 29.7 70.2 34.0 24.7 40.0 45.0 29.9 3.9 31.3 42.9 46.6 25.9 0.3 39.1 34.0 31.0 50.3 15.3 33.3 78.3 23.9 0.0 3.3 2.2 1.1 7.4 1.2 0.9 1.6 1.7 3.8 1.1 1.3 1.5 0.9 0.6 9.6 0.9 3.0 1.8 41.5 47.1 42.3 34.9 38.4 36.0 52.1 41.8 39.2 47.8 48.1 48.2 17.0 12.8 25.4 33.0 7.0 8.0 9.3 14.5 7.4 40.3 19.8 12.3 33.4 25.8 21.0 25.8 183.5 15.9 10.8 45.1 9.8 25.7 219.0 17.7 16.6 16.3 13.8 12.8 34.3 29.5 1.1 10.4 19.9 18.5 5.1 24.6 15.4 68.7 19.0 65.6 37.9 19.7 12.2 32.6 27.3 219.3 7.8 25.7 1.8 17.8 38.5 34.1 9.2 19.1 28.7 26.8 18.8 5.7 11.8 18.6 60.5 52.6 31.0 184.0 6.6 14.9 24.4 7.0 2.4 17.4 11.1 12.0 14.4 22.0 22.5 15.7 AHSP "EDRF, ERAF" ENSG00000169877 "Alpha hemoglobin stabilizing protein" Q9NZD4 16 31527900-31528803 "Plasma proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 62 "bone marrow: 1669.9" "Cell type enriched" "Detected in some" 296 "Erythroid cells: 8721.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTCEpi: 3.0;K-562: 1.5" "Low region specificity" "Detected in some" HPA040940 Enhanced NA NA 5300000 "Cluster 1: Neutrophils - Mixed function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 6: Erythroid cells - Oxygen transport" "HPA040940: AB_10796231" "unprognostic (3.00e-1)" "unprognostic (2.01e-1)" "unprognostic (8.44e-2)" "unprognostic (3.76e-1)" "unprognostic (1.53e-1)" "unprognostic (3.10e-1)" "unprognostic (2.16e-1)" "unprognostic (3.70e-3)" "unprognostic (2.04e-2)" "unprognostic (9.02e-2)" "unprognostic (3.25e-2)" 1.3 0.1 0.6 0.2 0.6 1669.9 0.4 0.6 2.6 0.4 0.6 0.1 0.0 0.1 0.0 0.2 0.2 0.0 1.5 0.6 0.5 1.9 4.7 4.5 0.2 0.7 0.7 0.2 0.3 0.1 1.4 27.1 0.7 0.1 0.3 0.0 0.5 0.0 0.2 1.4 0.1 0.0 0.6 23.7 0.2 4.1 0.6 2.9 0.7 8.9 0.0 0.2 0.3 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.8 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 4.7 0.6 0.6 0.6 2.6 0.6 0.5 0.7 0.7 0.7 0.6 0.6 0.8 0.1 0.0 0.0 0.0 9.7 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.5 0.0 0.0 0.6 0.0 8721.3 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 2.9 4.2 0.0 0.0 0.0 0.0 0.0 8.1 0.0 29.4 0.3 2.8 10.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 4.1 0.5 0.0 0.0 0.0 2.1 0.0 0.0 0.1 AK4 "AK3, AK3L1" ENSG00000162433 "Adenylate kinase 4" P27144 1 65147549-65232145 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 183.5;liver: 104.0" "Cell type enhanced" "Detected in many" "Hepatocytes: 242.6;Proximal tubular cells: 595.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 3.1;myeloid DC: 2.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Hep G2: 208.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042753, HPA049461" Enhanced Supported Mitochondria "Intracellular and membrane" NA Yes 39000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA042753: AB_2678146, HPA049461: AB_2680776" "unprognostic (3.73e-2)" "prognostic unfavorable (4.17e-4)" "unprognostic (2.25e-1)" "unprognostic (3.05e-3)" "unprognostic (1.48e-2)" "prognostic unfavorable (8.83e-4)" "unprognostic (1.16e-3)" "unprognostic (3.89e-2)" "unprognostic (4.03e-1)" "unprognostic (5.39e-2)" "prognostic unfavorable (4.34e-5)" "unprognostic (6.71e-2)" "prognostic unfavorable (4.36e-4)" "prognostic unfavorable (4.87e-4)" "unprognostic (2.69e-1)" "unprognostic (7.07e-2)" "unprognostic (7.57e-2)" 24.7 1.9 19.5 6.6 21.0 4.9 26.6 17.8 20.8 6.1 17.5 19.7 4.3 7.0 4.2 23.4 7.6 13.7 51.7 21.4 21.2 183.5 104.0 2.8 1.6 19.0 22.8 4.6 1.2 18.3 4.7 8.3 22.8 16.2 14.0 21.9 9.6 12.7 1.7 27.4 6.6 21.4 18.5 1.2 15.0 11.3 22.7 5.7 2.5 38.8 3.3 19.1 11.8 21.1 73.2 5.0 5.6 23.9 51.6 48.7 12.0 12.1 15.0 25.6 70.8 108.1 8.6 39.1 31.0 19.0 32.1 46.1 18.8 89.9 101.9 33.0 21.5 37.9 21.9 208.6 2.5 29.9 4.6 27.2 49.6 25.1 73.0 42.2 0.9 12.2 48.0 0.6 39.6 31.2 1.1 1.3 24.6 1.0 42.5 0.2 41.0 7.1 37.8 3.2 20.5 15.4 21.6 1.5 16.7 25.8 29.7 12.9 4.2 42.4 36.2 3.3 20.9 39.5 18.8 2.1 68.7 10.9 2.5 0.9 3.1 0.0 0.1 0.6 0.2 0.2 0.1 0.2 2.7 0.1 0.1 0.1 0.4 0.3 0.1 0.4 0.0 0.8 19.5 21.0 17.8 20.8 21.4 21.2 19.0 22.8 22.8 18.5 22.7 21.1 11.2 0.0 0.5 51.2 4.7 49.7 23.6 44.2 63.7 24.5 48.9 44.7 105.7 52.9 14.3 31.3 2.1 2.2 0.6 15.8 56.7 18.6 3.4 30.1 8.2 19.6 5.4 13.9 17.1 12.1 21.1 11.4 27.5 52.2 0.0 36.4 11.7 242.6 3.3 16.8 7.7 8.7 24.4 7.8 9.2 5.8 4.1 6.9 24.9 3.7 5.7 32.7 0.0 9.5 2.5 31.9 4.3 9.4 0.4 38.7 18.8 595.5 12.3 6.5 6.6 5.6 18.8 1.8 9.5 43.1 74.3 4.9 3.6 0.7 23.1 20.4 AK7 "CFAP75, FAP75, FLJ32864" ENSG00000140057 "Adenylate kinase 7" Q96M32 14 96392128-96489427 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 24.3" "Group enriched" "Detected in many" 4 "Endometrial ciliated cells: 97.9;Respiratory ciliated cells: 137.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 23 "basophil: 9.0" "Lineage enriched" "Detected in single" 29 "granulocytes: 9.0" "Cell line enhanced" "Detected in many" "BEWO: 17.0;CAPAN-2: 15.1;MCF7: 49.5;REH: 35.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA003543 Enhanced NA NA "Cluster 38: Basophils - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 49: Ciliated cells - Cilium organization" "HPA003543: AB_1078117" "unprognostic (4.18e-3)" "unprognostic (1.14e-1)" "unprognostic (9.40e-3)" "prognostic favorable (3.18e-4)" "unprognostic (4.98e-5)" "unprognostic (8.41e-2)" "unprognostic (9.81e-3)" "unprognostic (1.29e-1)" "unprognostic (9.02e-2)" "unprognostic (3.65e-4)" "unprognostic (8.64e-2)" "unprognostic (1.89e-1)" "prognostic favorable (1.14e-4)" "unprognostic (2.00e-2)" "unprognostic (1.23e-2)" "unprognostic (4.01e-2)" "unprognostic (2.25e-3)" 0.7 2.6 2.0 0.6 3.1 1.5 1.4 1.1 1.7 1.7 13.2 2.1 1.9 2.1 3.9 1.5 24.3 2.6 0.7 2.2 5.2 4.5 1.6 4.2 0.6 6.9 9.4 0.4 2.2 6.9 5.1 0.5 5.6 0.9 1.6 3.0 1.0 1.3 0.3 6.1 1.2 1.1 4.4 3.3 2.8 7.6 5.0 0.5 2.7 0.0 0.4 0.5 1.0 4.2 0.2 4.9 2.0 1.5 0.8 2.6 17.0 0.3 0.6 0.3 0.3 0.5 15.1 0.4 0.3 0.0 0.3 1.9 4.7 0.2 0.1 2.2 0.4 0.4 2.4 0.2 0.8 0.1 0.3 0.2 0.6 2.5 0.1 0.8 0.2 1.4 0.2 0.3 0.3 49.5 0.3 0.3 0.8 2.2 1.0 35.2 0.3 0.4 7.6 0.3 3.1 6.7 1.9 0.6 0.1 1.8 4.2 0.2 0.1 0.4 0.2 0.6 0.2 0.6 2.3 0.2 0.2 0.0 0.7 9.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.3 0.0 0.2 0.1 0.1 0.3 0.2 0.2 0.0 0.0 0.1 2.0 3.1 1.1 1.7 2.2 5.2 6.9 9.4 5.6 4.4 5.0 4.2 1.6 6.4 4.1 0.7 0.8 1.8 0.9 3.6 1.8 0.2 0.9 0.3 0.4 4.3 12.3 7.3 2.1 0.7 0.1 1.4 3.9 3.2 18.7 97.9 1.7 1.9 1.2 6.9 2.0 1.1 1.7 0.8 5.1 11.6 0.0 0.1 0.7 2.4 0.2 0.0 2.4 0.3 4.1 0.3 0.4 4.1 0.0 0.5 1.8 0.0 0.0 0.6 0.0 0.5 3.7 0.5 0.1 0.0 0.0 0.5 1.0 3.4 137.1 1.8 0.0 0.4 1.6 25.4 9.1 0.7 3.0 2.9 0.2 1.5 1.2 0.6 AL354761.1 ENSG00000236543 "Lipocalin 1-like" 9 135604345-135619893 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 31 "skin 1: 8.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 24 "BEWO: 3.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 61: Skin - Cornification" "Cluster 28: BEWO - Transcription regulation" 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ALOX15B 15-LOX-2 ENSG00000179593 "Arachidonate 15-lipoxygenase type B" O15296 17 8039034-8049134 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 111.7;prostate: 73.1" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 75.8;Basal respiratory cells: 22.0;Kupffer cells: 42.2;monocytes: 87.9;Prostatic glandular cells: 25.6;Squamous epithelial cells: 44.4" "Cancer enriched" "Detected in all" 5 "prostate cancer: 91.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 8 "classical monocyte: 3.9;myeloid DC: 4.3" "Group enriched" "Detected in many" 8 "dendritic cells: 4.3;monocytes: 3.9" "Cell line enhanced" "Detected in some" "HHSteC: 7.7;HSkMC: 16.6;hTCEpi: 35.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA010562 Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 3: Monocytes - Immune response regulation" "Plasma membrane, Cytosol" "HPA010562: AB_2668305" "unprognostic (1.76e-2)" "unprognostic (6.47e-2)" "unprognostic (2.56e-1)" "unprognostic (2.28e-3)" "unprognostic (1.67e-2)" "unprognostic (1.52e-1)" "unprognostic (1.34e-1)" "unprognostic (1.52e-1)" "unprognostic (2.28e-1)" "unprognostic (1.85e-1)" "unprognostic (1.44e-2)" "unprognostic (4.59e-1)" "unprognostic (1.59e-2)" "unprognostic (9.37e-2)" "unprognostic (1.48e-1)" "unprognostic (2.32e-2)" "unprognostic (9.49e-2)" 2.2 1.7 0.7 1.3 0.7 0.4 111.7 0.6 2.5 12.0 0.5 2.3 0.1 1.1 0.9 39.1 1.6 0.7 0.7 0.7 0.8 0.5 0.4 24.5 2.9 1.8 0.9 0.7 1.4 0.2 0.5 1.2 1.6 73.1 0.3 0.3 3.7 0.1 0.3 36.9 3.7 0.1 0.9 3.8 4.4 0.5 0.9 0.7 1.9 0.1 7.6 1.7 33.4 1.9 0.1 0.0 0.0 0.1 0.5 0.7 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 16.6 35.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.2 0.5 0.0 0.1 0.0 0.9 0.7 0.7 0.6 2.5 0.7 0.8 1.8 0.9 1.6 0.9 0.9 1.9 1.4 0.0 75.8 0.0 0.3 3.1 0.6 22.0 7.4 0.0 19.8 12.3 0.3 1.5 8.2 0.0 0.0 0.2 0.2 0.2 0.0 0.1 1.3 0.0 0.8 0.4 0.0 0.0 0.2 0.4 0.0 0.2 0.0 0.2 1.3 0.0 0.7 0.3 4.2 0.0 0.0 0.0 2.0 42.2 1.1 0.8 0.0 15.4 5.4 0.0 87.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.4 25.6 0.0 0.0 2.2 0.0 0.0 0.1 1.3 0.6 0.8 44.4 1.1 0.8 0.0 0.0 0.0 2.2 ANKRD18A "FLJ35740, KIAA2015" ENSG00000180071 "Ankyrin repeat domain 18A" Q8IVF6 9 38571358-38620596 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 18.2;brain: 21.9" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 33.3;Excitatory neurons: 24.8;Inhibitory neurons: 26.8;Oligodendrocytes: 118.1;Rod photoreceptor cells: 31.2;Spermatocytes: 53.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HL-60: 17.9" "HPA046346, HPA046695, HPA049923, HPA051288" Uncertain Uncertain "Nucleoli,Nucleoli rim,Cytosol" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 43: THP-1 - Innate immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoli, Nucleoli rim" Cytosol "HPA046346: AB_2679631, HPA046695: , HPA049923: AB_2680954, HPA051288: AB_2681421" "unprognostic (4.02e-2)" "unprognostic (1.07e-1)" "unprognostic (1.42e-3)" "unprognostic (1.69e-2)" "unprognostic (2.05e-1)" "unprognostic (2.38e-2)" "unprognostic (1.26e-1)" "unprognostic (2.37e-1)" "unprognostic (4.34e-1)" "unprognostic (1.15e-1)" "unprognostic (1.92e-2)" "unprognostic (1.94e-5)" "unprognostic (2.31e-2)" "unprognostic (1.63e-2)" "unprognostic (1.58e-2)" "unprognostic (7.03e-2)" "unprognostic (2.14e-1)" 0.0 0.1 3.0 0.3 9.1 18.2 0.4 3.6 3.7 0.4 0.0 0.5 0.3 0.2 0.2 0.8 0.5 0.4 0.6 3.1 5.1 0.9 0.7 0.3 0.2 12.6 6.0 0.0 2.2 0.6 1.0 0.1 14.3 0.9 0.7 5.0 0.4 0.1 0.0 1.3 0.7 0.2 5.1 0.1 1.0 7.2 8.4 0.3 2.2 0.0 0.1 0.2 0.4 21.9 4.8 3.7 3.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.6 0.0 1.9 0.0 0.0 0.9 3.5 3.4 0.0 0.0 5.2 0.0 5.6 2.9 0.0 17.9 0.5 0.0 2.3 0.0 3.1 1.7 0.0 7.2 1.7 0.4 0.3 4.6 0.1 0.9 3.7 6.2 2.1 0.0 6.5 6.8 2.1 2.0 1.5 3.0 2.4 0.5 0.2 7.1 2.6 8.3 4.5 0.0 1.3 0.1 0.0 0.3 0.6 0.0 0.0 0.0 2.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 3.0 9.1 3.6 3.7 3.1 5.1 12.6 6.0 14.3 5.1 8.4 21.9 0.1 0.0 1.5 1.0 0.1 0.6 2.0 1.5 3.4 3.8 2.3 2.4 9.4 1.5 3.7 1.8 2.1 0.0 0.1 0.8 1.9 5.4 8.0 33.3 1.7 0.2 4.2 0.0 24.8 2.4 0.9 0.2 7.7 19.2 0.0 14.7 0.0 0.5 0.1 0.0 26.8 3.3 2.0 0.0 0.3 2.2 0.6 0.2 0.0 1.0 0.4 9.2 0.0 18.1 118.1 3.9 2.6 0.4 0.1 1.9 1.6 0.3 11.0 31.2 0.0 0.0 0.3 53.5 4.3 3.8 1.7 0.0 1.4 0.3 2.3 1.4 ANKRD2 ARPP ENSG00000165887 "Ankyrin repeat domain 2" Q9GZV1 10 97572499-97583884 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 63 "heart muscle: 437.1;skeletal muscle: 981.2;tongue: 823.8" "Cell type enriched" "Detected in some" 6 "Cardiomyocytes: 218.3" "Cancer enhanced" "Detected in many" "renal cancer: 4.9;testis cancer: 5.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 17.6;BJ hTERT+ SV40 Large T+: 7.3;HaCaT: 13.0;RPTEC TERT1: 17.4" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA040842, HPA040884" Enhanced Enhanced Vesicles NA NA 110000 "Cluster 1: Neutrophils - Mixed function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" Vesicles "HPA040842: AB_10963794, HPA040884: AB_10969453" "unprognostic (1.27e-2)" "unprognostic (9.99e-2)" "unprognostic (2.86e-1)" "unprognostic (1.39e-2)" "unprognostic (1.37e-1)" "unprognostic (1.61e-2)" "unprognostic (2.53e-1)" "unprognostic (5.60e-3)" "unprognostic (2.17e-1)" "unprognostic (3.12e-1)" "unprognostic (4.91e-2)" "unprognostic (2.22e-1)" "unprognostic (1.05e-2)" "unprognostic (3.69e-3)" "unprognostic (4.56e-2)" "unprognostic (1.39e-1)" "unprognostic (2.13e-1)" 0.4 0.8 2.5 0.1 2.3 0.0 0.5 2.5 3.7 0.2 2.0 0.3 0.0 0.3 0.3 1.0 0.1 0.3 437.1 2.5 2.7 11.8 0.3 0.8 0.2 2.5 2.4 0.1 0.9 0.0 0.6 0.0 2.5 2.9 0.0 0.3 3.4 0.9 981.2 2.7 0.2 0.2 1.9 0.1 0.2 0.5 2.7 0.0 0.5 823.8 0.1 0.1 0.4 2.5 17.6 5.4 0.0 0.0 0.2 0.0 0.4 0.9 0.0 7.3 4.7 0.3 5.3 0.0 0.6 0.2 0.4 13.0 0.0 4.7 5.0 0.2 0.2 0.0 0.3 0.0 0.5 0.0 0.0 0.8 2.1 4.3 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 17.4 0.8 0.0 0.0 0.0 4.4 0.0 0.4 2.1 0.3 0.0 0.1 1.5 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.5 2.3 2.5 3.7 2.5 2.7 2.5 2.4 2.5 1.9 2.7 2.5 0.1 0.0 0.0 1.3 0.0 0.1 0.7 1.7 1.2 0.0 0.2 0.4 218.3 2.8 0.2 3.7 0.0 0.2 0.0 0.0 31.3 1.2 0.6 0.1 0.3 1.6 0.0 0.0 1.3 0.2 0.4 1.0 0.0 0.1 0.0 0.7 0.4 0.2 0.1 0.0 1.5 0.0 0.0 0.0 0.4 0.2 0.0 0.3 0.0 0.0 1.6 0.0 0.0 0.5 0.4 0.9 0.0 1.9 0.0 0.1 0.0 19.1 0.0 0.1 0.0 13.6 1.1 2.5 3.5 0.6 0.3 0.3 0.2 0.1 0.0 0.5 ANKRD22 MGC22805 ENSG00000152766 "Ankyrin repeat domain 22" Q5VYY1 10 88819896-88851844 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 33.8;skin 1: 30.9;stomach 1: 46.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 37.2;Distal enterocytes: 38.2;Gastric mucus-secreting cells: 49.5;Paneth cells: 51.5;Squamous epithelial cells: 35.8;Suprabasal keratinocytes: 102.9;Urothelial cells: 30.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "neutrophil: 6.4" "Group enriched" "Detected in many" 14 "granulocytes: 6.4;monocytes: 3.1" "Cell line enhanced" "Detected in some" "A-431: 8.6;CAPAN-2: 26.1;HL-60: 9.4;NB-4: 8.7;OE19: 20.9;RT4: 16.4;T-47d: 12.2;U-937: 7.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA012922 Approved Approved Nucleoplasm NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA012922: AB_1844838" "unprognostic (1.86e-1)" "unprognostic (1.48e-3)" "unprognostic (9.73e-3)" "prognostic favorable (8.73e-6)" "unprognostic (1.18e-1)" "unprognostic (2.81e-2)" "unprognostic (2.39e-2)" "unprognostic (1.50e-1)" "unprognostic (4.57e-2)" "unprognostic (7.21e-3)" "prognostic unfavorable (6.15e-4)" "unprognostic (1.09e-3)" "unprognostic (1.05e-2)" "unprognostic (4.87e-3)" "unprognostic (4.17e-2)" "unprognostic (3.18e-3)" "unprognostic (1.01e-3)" 0.2 0.3 0.6 9.5 0.7 5.4 2.6 0.5 0.9 7.6 0.4 7.2 2.7 0.2 0.3 33.8 0.3 3.2 0.1 0.5 0.7 4.7 2.0 1.5 4.2 1.3 0.8 0.3 12.9 0.8 0.3 0.2 1.1 2.5 7.1 0.1 4.9 0.1 0.1 30.9 2.1 1.6 0.6 6.4 46.3 0.1 0.7 5.5 0.1 0.0 7.8 4.8 13.9 0.9 8.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.1 0.0 0.1 0.0 0.0 6.5 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 9.4 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.0 0.1 0.6 8.7 0.0 20.9 0.1 0.0 0.0 0.0 0.0 16.4 0.0 0.0 0.0 1.3 0.0 0.0 12.2 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 7.9 0.0 0.0 2.1 1.1 0.0 3.1 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.0 6.4 0.2 0.6 0.2 0.0 0.6 0.6 0.7 0.5 0.9 0.5 0.7 1.3 0.8 1.1 0.6 0.7 0.9 0.0 0.0 3.7 0.0 1.0 37.2 18.6 7.6 1.8 0.0 1.5 0.9 0.2 5.7 4.5 7.3 0.0 0.0 0.0 38.2 0.0 3.2 0.0 0.9 0.5 0.3 1.8 0.4 0.0 5.9 0.0 0.6 49.5 4.8 0.0 0.0 0.0 0.6 2.2 0.0 0.0 14.9 16.2 9.3 3.1 0.2 0.3 8.5 1.8 0.0 2.2 0.0 0.0 0.0 0.0 5.7 51.5 0.0 0.2 10.1 0.6 0.0 1.7 0.0 0.0 0.1 0.3 0.1 0.2 35.8 102.9 0.0 0.8 0.1 25.7 30.3 ANKRD35 FLJ25124 ENSG00000198483 "Ankyrin repeat domain 35" Q8N283 1 145866560-145885866 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 60.8" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 56.4;Fibroblasts: 31.2;Leydig cells: 36.4;Muller glia cells: 57.7;Peritubular cells: 50.8;Skeletal myocytes: 29.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 2.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "ASC TERT1: 9.6;THP-1: 6.8;TIME: 8.4;U-87 MG: 8.3;U-937: 7.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA035453 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 32: U-937 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" Nucleoplasm "HPA035453: AB_10672864" "prognostic favorable (9.35e-4)" "prognostic favorable (2.90e-4)" "unprognostic (2.07e-1)" "unprognostic (7.39e-3)" "unprognostic (1.77e-2)" "unprognostic (1.02e-2)" "unprognostic (3.27e-1)" "unprognostic (3.58e-2)" "unprognostic (3.03e-1)" "unprognostic (1.79e-1)" "unprognostic (2.98e-1)" "unprognostic (5.86e-2)" "unprognostic (9.29e-10)" "unprognostic (8.80e-3)" "unprognostic (2.18e-1)" "unprognostic (5.92e-2)" "unprognostic (8.69e-3)" 4.0 1.3 8.2 1.1 7.9 0.3 4.6 7.6 9.7 20.6 6.4 6.0 0.5 5.8 1.4 24.7 6.6 1.3 2.9 7.5 8.6 0.8 2.5 2.3 0.4 8.7 9.5 4.4 0.7 0.0 2.0 0.1 8.5 6.6 0.8 1.3 11.4 2.7 8.2 60.8 2.5 2.1 8.4 0.5 3.9 1.6 9.0 0.5 1.7 3.8 6.7 7.3 20.6 7.6 0.1 0.0 0.0 0.0 2.2 9.6 0.2 1.4 3.6 0.4 1.2 0.4 0.0 0.0 0.3 1.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 2.9 0.0 0.0 1.1 2.9 0.1 3.3 0.4 0.3 0.0 0.1 0.4 0.0 0.0 0.0 2.2 0.0 0.0 3.9 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 8.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 8.3 7.5 0.0 0.0 2.1 0.0 0.7 0.8 0.1 0.0 0.3 1.1 0.3 0.0 0.2 0.7 0.1 0.7 0.2 0.5 0.7 0.7 8.2 7.9 7.6 9.7 7.5 8.6 8.7 9.5 8.5 8.4 9.0 7.6 1.6 0.0 0.0 6.8 0.3 4.6 16.8 10.2 0.0 1.1 6.3 13.5 1.5 2.8 9.5 1.8 0.0 0.1 2.2 0.0 0.0 0.0 3.5 56.4 10.9 1.3 0.0 2.7 5.6 0.4 0.1 31.2 0.5 17.2 19.1 0.0 2.2 13.9 11.0 0.0 2.1 0.0 14.2 1.2 4.6 5.9 36.4 1.1 5.4 1.0 1.1 57.7 5.2 3.0 0.6 0.1 0.0 50.8 0.4 5.3 0.0 0.1 9.8 2.7 0.0 29.5 6.4 0.1 1.0 10.4 12.4 0.3 5.5 1.1 0.0 13.6 APMAP "BSCv, C20orf3" ENSG00000101474 "Adipocyte plasma membrane associated protein" Q9HDC9 20 24962925-24992751 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 314.0" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 325.4;Hepatocytes: 251.1;Syncytiotrophoblasts: 751.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "granulocytes: 680.7;NK-cells: 343.8;T-cells: 367.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012863, HPA064700" Approved Approved "Plasma membrane" NA NA 130000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane" "HPA012863: AB_1845683, HPA064700: AB_2685328" "unprognostic (4.07e-3)" "unprognostic (2.50e-2)" "unprognostic (1.20e-1)" "unprognostic (8.16e-2)" "unprognostic (6.79e-2)" "unprognostic (2.14e-2)" "unprognostic (1.10e-2)" "unprognostic (4.09e-2)" "unprognostic (3.10e-2)" "unprognostic (1.19e-2)" "unprognostic (6.46e-2)" "unprognostic (1.54e-1)" "unprognostic (7.99e-3)" "unprognostic (8.26e-2)" "unprognostic (1.67e-1)" "unprognostic (1.23e-1)" "unprognostic (3.51e-2)" 168.0 44.6 59.2 47.2 60.1 187.4 84.6 76.0 65.4 41.8 62.2 46.5 32.7 46.8 106.3 26.7 46.0 43.1 37.5 64.1 72.6 50.5 314.0 53.2 44.0 61.4 62.8 40.8 45.2 83.4 78.7 80.2 68.6 44.2 42.9 32.0 40.1 47.9 39.5 55.8 34.7 49.2 60.5 66.6 38.5 54.2 69.7 42.4 209.1 24.4 34.1 51.8 29.5 68.8 110.6 191.3 90.0 139.5 175.3 97.5 94.4 141.8 153.4 133.3 137.4 113.7 189.3 45.9 161.1 170.6 232.1 198.1 85.0 165.1 149.1 62.3 69.7 51.2 66.0 226.9 140.9 99.5 115.4 134.3 226.9 154.9 107.0 173.8 192.5 73.4 61.5 195.8 128.6 168.1 68.9 108.2 59.3 166.6 172.1 56.3 312.8 96.3 140.2 98.9 150.6 59.4 146.9 240.5 157.1 92.0 87.6 78.8 173.7 156.9 140.6 134.7 209.5 113.0 134.3 50.9 83.1 148.0 151.9 61.8 99.3 198.9 367.9 98.6 228.8 36.4 100.8 268.2 102.1 37.4 78.6 202.2 680.7 343.8 71.3 50.7 75.0 363.3 59.2 60.1 76.0 65.4 64.1 72.6 61.4 62.8 68.6 60.5 69.7 68.8 28.5 19.2 32.7 25.8 22.2 24.3 46.7 77.6 17.1 51.4 48.1 32.1 17.5 34.3 39.7 49.7 10.4 325.4 163.2 18.9 17.6 72.0 22.9 18.0 26.3 42.4 18.0 33.6 24.0 45.4 50.6 40.6 15.3 23.8 36.1 68.6 41.4 251.1 95.9 16.8 25.4 19.4 85.5 50.0 94.8 32.5 65.0 59.5 46.2 42.2 105.1 35.0 222.5 19.6 15.9 40.8 25.4 82.0 54.9 34.1 20.8 13.2 24.5 22.5 39.5 36.9 33.2 97.1 90.1 16.7 20.0 751.1 96.7 38.3 28.0 28.1 APOC1 ENSG00000130208 "Apolipoprotein C1" P02654 19 44914247-44919349 "Cancer-related genes, Candidate cardiovascular disease genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Lipid transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 8 "liver: 16232.1" "Cell type enriched" "Detected in many" 6 "Hepatocytes: 33405.9" "Cancer enriched" "Detected in all" 21 "liver cancer: 3253.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "myeloid DC: 5.6" "Lineage enriched" "Detected in single" 12 "dendritic cells: 5.6" "Cell line enhanced" "Detected in many" "Hep G2: 576.4;HSkMC: 332.9;K-562: 151.6;SK-MEL-30: 268.0" "Low region specificity" "Detected in all" HPA051518 Supported "Secreted to blood" NA NA 20300000000 15000000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "HPA051518: AB_2681519" "unprognostic (3.51e-2)" "unprognostic (3.31e-3)" "unprognostic (1.14e-1)" "unprognostic (2.59e-2)" "unprognostic (2.06e-1)" "unprognostic (1.47e-1)" "prognostic favorable (1.15e-7)" "unprognostic (9.51e-3)" "unprognostic (1.30e-1)" "unprognostic (4.18e-2)" "unprognostic (1.11e-1)" "unprognostic (2.52e-1)" "unprognostic (7.13e-3)" "unprognostic (3.48e-3)" "unprognostic (1.65e-1)" "unprognostic (2.01e-3)" "unprognostic (1.65e-1)" 59.2 1998.1 90.3 28.1 133.0 52.2 87.1 83.3 338.1 29.0 73.6 29.1 13.1 11.0 42.0 5.9 21.2 31.0 10.9 75.3 109.8 14.6 16232.1 289.9 140.1 133.2 152.8 56.4 21.4 16.3 23.6 41.7 121.9 14.4 16.7 15.1 35.5 2.2 22.2 73.1 49.1 4.0 92.7 254.9 22.7 18.7 139.2 37.4 36.3 6.1 33.9 23.5 11.3 169.4 2.7 26.5 12.0 5.0 37.1 38.2 111.5 1.3 1.7 4.8 7.3 55.6 49.9 8.4 9.4 1.0 3.2 1.8 15.6 1.9 2.3 0.4 63.5 36.8 4.2 576.4 32.9 27.5 18.1 332.9 2.8 4.8 1.8 9.2 1.3 1.8 151.6 0.8 1.7 3.6 1.5 2.0 112.4 10.4 5.6 6.2 16.0 0.8 7.3 2.0 5.3 3.3 18.9 0.3 268.0 37.7 2.2 98.4 4.2 0.4 1.7 0.2 1.7 4.5 5.4 8.2 0.7 7.4 2.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 5.6 0.1 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.3 90.3 133.0 83.3 338.1 75.3 109.8 133.2 152.8 121.9 92.7 139.2 169.4 22.9 115.4 214.4 2.3 40.6 17.0 4.1 5.8 6.2 2.5 49.8 92.8 0.8 453.2 55.8 1.8 0.0 31.7 1.6 2.4 49.0 4.6 1.2 6.6 128.4 68.9 2.4 768.8 0.3 4.0 341.3 93.0 19.4 5.0 142.6 30.6 432.6 33405.9 4789.8 0.0 0.5 3.2 4.1 867.7 27.3 22.8 270.9 620.5 30.2 3.7 124.5 276.0 0.0 0.0 0.0 3.2 0.3 259.5 1.3 4.2 0.6 16.6 24.4 9.9 19.7 1628.8 24.4 2.0 3.2 3.7 17.8 71.6 46.7 1226.7 2.1 5.0 AQP3 GIL ENSG00000165272 "Aquaporin 3 (Gill blood group)" Q92482 9 33441156-33447596 "Blood group antigen proteins, Metabolic proteins, Plasma proteins, Predicted membrane proteins" Transport "Blood group antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 1526.1;skin 1: 581.9;urinary bladder: 688.6" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 1923.3;Basal prostatic cells: 982.0;Collecting duct cells: 1609.3;Prostatic glandular cells: 1430.8;Squamous epithelial cells: 2189.3;Suprabasal keratinocytes: 2485.4;Urothelial cells: 2455.4" "Group enriched" "Detected in all" 5 "cervical cancer: 319.0;head and neck cancer: 283.7;lung cancer: 146.8;urothelial cancer: 221.3" "Group enriched" "Detected in many" 4 "hippocampal formation: 5.3;medulla oblongata: 16.0;pons: 21.0" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 181.7;T-reg: 205.4" "Lineage enriched" "Detected in many" 18 "T-cells: 205.4" "Cell line enhanced" "Detected in many" "HaCaT: 127.1;HeLa: 213.2;JURKAT: 130.7;RT4: 216.6;SK-BR-3: 149.7;U-266/70: 151.2;U-266/84: 213.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA014924 Enhanced Supported "Plasma membrane" NA NA "Cluster 13: T-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane" "HPA014924: AB_2669120" "unprognostic (4.29e-2)" "prognostic favorable (5.31e-4)" "unprognostic (1.15e-1)" "unprognostic (3.26e-2)" "unprognostic (1.84e-2)" "unprognostic (1.11e-2)" "unprognostic (9.95e-2)" "unprognostic (1.64e-1)" "unprognostic (3.46e-1)" "unprognostic (9.06e-2)" "unprognostic (4.87e-2)" "unprognostic (1.25e-1)" "unprognostic (1.54e-2)" "unprognostic (1.16e-2)" "unprognostic (2.59e-1)" "unprognostic (3.73e-2)" "unprognostic (4.51e-2)" 10.9 2.1 1.5 16.8 0.4 19.7 36.6 2.4 3.4 173.3 1.4 10.3 73.4 10.9 2.9 1526.1 25.4 9.4 31.5 5.3 0.4 131.7 118.6 114.0 16.1 16.0 1.6 12.1 43.1 2.0 2.8 6.0 21.0 85.6 10.1 1.7 399.7 36.8 5.3 581.9 100.5 3.2 0.2 110.1 35.9 2.8 0.8 233.9 2.3 26.7 172.5 688.6 529.9 0.9 0.6 38.6 1.9 0.0 67.7 12.2 1.0 0.3 0.9 0.9 1.1 20.5 12.0 0.5 9.1 0.0 0.5 127.1 6.2 0.7 0.2 61.6 6.0 4.3 213.2 1.9 0.4 1.3 1.3 1.9 6.5 0.5 0.2 0.2 0.5 130.7 67.4 58.8 6.9 29.1 60.4 23.0 5.3 88.6 0.7 0.9 94.3 10.8 1.3 216.6 1.7 4.7 32.3 149.7 0.1 8.0 0.9 10.6 1.2 0.0 1.0 0.4 0.4 151.2 213.6 14.5 0.5 0.4 0.2 1.6 0.5 0.1 20.2 0.4 181.7 11.3 171.9 52.8 0.3 3.0 97.3 47.1 2.3 3.0 0.5 11.1 205.4 43.0 1.5 0.4 2.4 3.4 5.3 0.4 16.0 1.6 21.0 0.2 0.8 0.9 9.2 38.5 249.9 0.0 42.4 1923.3 982.0 381.4 811.0 9.7 56.8 27.8 3.4 157.3 436.3 1609.3 2.1 0.9 21.6 2.7 0.0 37.4 2.2 82.3 21.4 37.1 8.3 71.4 0.3 48.9 2.0 27.5 16.3 96.2 20.8 0.2 16.4 137.3 2.2 0.0 0.1 104.0 315.3 3.5 122.9 0.6 33.2 15.3 158.3 0.0 1.6 0.4 4.1 0.5 0.2 28.5 8.1 1.2 246.9 1430.8 343.1 31.9 546.0 0.5 0.0 10.2 35.8 0.7 1.9 2189.3 2485.4 50.2 73.4 1.6 7.3 2455.4 AQP5 ENSG00000161798 "Aquaporin 5" P55064 12 49961872-49965682 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 622.6;testis: 222.0" "Group enriched" "Detected in many" 7 "Early spermatids: 1542.9;Late spermatids: 4265.6" "Cancer enhanced" "Detected in many" "endometrial cancer: 87.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 22 "OE19: 223.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA065008 Enhanced Approved "Plasma membrane" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 31: Spermatids - Spermatogenesis" "Plasma membrane" "HPA065008: AB_2685401" "unprognostic (4.67e-3)" "unprognostic (5.00e-2)" "unprognostic (3.30e-1)" "unprognostic (6.00e-3)" "unprognostic (1.92e-3)" "prognostic favorable (1.75e-5)" "unprognostic (4.13e-3)" "unprognostic (1.02e-2)" "unprognostic (9.39e-2)" "unprognostic (3.70e-3)" "unprognostic (2.88e-3)" "unprognostic (2.46e-3)" "unprognostic (1.69e-4)" "unprognostic (2.53e-1)" "unprognostic (5.28e-2)" "unprognostic (2.51e-3)" "unprognostic (9.11e-3)" 2.9 0.8 2.7 0.1 3.7 0.2 17.1 3.3 2.7 12.9 1.5 0.4 15.3 2.7 0.2 16.5 0.7 2.8 4.0 2.4 2.9 1.9 0.1 7.6 0.0 3.3 3.9 0.2 2.0 3.0 1.2 0.0 3.1 1.3 0.0 1.0 622.6 1.0 0.2 112.7 0.1 0.3 2.6 0.4 52.3 222.0 3.8 0.0 1.6 0.0 0.1 0.3 0.4 2.6 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 8.7 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.7 223.2 0.0 10.1 0.0 0.0 0.3 0.0 0.2 0.1 0.8 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 3.7 3.3 2.7 2.4 2.9 3.3 3.9 3.1 2.6 3.8 2.6 0.5 57.7 3.1 0.0 0.1 1.3 0.5 18.3 0.0 0.8 53.9 48.0 0.3 0.0 56.4 7.3 0.0 0.0 0.1 0.0 0.0 0.1 1542.9 1.5 0.1 1.8 0.0 0.0 0.0 0.2 0.0 1.4 34.7 2.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 26.4 0.0 1.6 4265.6 28.6 1.7 295.3 0.0 0.0 53.7 0.0 3.0 0.1 7.2 0.0 19.2 0.3 1.6 0.0 0.0 9.7 1.7 19.7 0.0 1.8 403.9 15.9 1.3 0.9 0.0 0.6 18.7 0.0 0.6 AQP6 AQP2L ENSG00000086159 "Aquaporin 6" Q13520 12 49967194-49977139 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "kidney: 52.7" "Cell type enhanced" "Detected in some" "Astrocytes: 4.2;Cardiomyocytes: 8.3;Collecting duct cells: 5.5;Ionocytes: 2.0" "Cancer enriched" "Detected in many" 9 "renal cancer: 9.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "OE19: 1.4" "Region enriched" "Detected in some" 7 "cerebellum: 21.0" "Not detected" "Not detected" HPA015278 Enhanced NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA015278: AB_10600982" "unprognostic (1.23e-1)" "unprognostic (1.32e-2)" "unprognostic (9.53e-2)" "unprognostic (2.02e-2)" "unprognostic (6.46e-2)" "unprognostic (4.60e-3)" "unprognostic (3.45e-2)" "unprognostic (1.46e-2)" "unprognostic (1.36e-1)" "unprognostic (8.68e-3)" "unprognostic (1.71e-1)" "unprognostic (2.00e-1)" "unprognostic (1.74e-1)" "unprognostic (6.85e-2)" "unprognostic (9.22e-2)" "unprognostic (9.03e-2)" "unprognostic (1.77e-1)" 0.1 0.2 2.8 0.1 4.1 0.0 0.1 5.6 2.6 0.3 1.6 0.6 0.1 0.1 0.2 0.1 0.1 0.1 0.2 2.7 2.5 52.7 0.3 0.1 0.0 4.9 4.6 0.0 0.1 0.2 0.2 0.0 5.2 0.2 0.0 0.2 1.0 0.2 0.0 0.3 0.2 0.1 3.4 0.0 0.4 2.4 6.1 0.0 0.0 0.0 0.0 0.1 0.1 3.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.1 1.4 0.1 0.2 0.0 0.1 0.2 0.0 0.1 0.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 4.1 5.6 2.6 2.7 2.5 4.9 4.6 5.2 3.4 6.1 3.3 0.0 0.0 0.0 4.2 0.1 0.0 0.0 0.6 0.0 0.1 0.4 0.3 8.3 0.0 0.9 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 2.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 1.5 1.6 0.0 0.0 0.4 0.0 0.0 0.0 1.0 0.2 0.6 0.0 0.0 0.1 0.5 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 AQP9 "HsT17287, SSC1" ENSG00000103569 "Aquaporin 9" O43315 15 58138169-58185911 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "liver: 702.7" "Group enriched" "Detected in some" 4 "Hepatocytes: 313.9;Macrophages: 82.1" "Cancer enriched" "Detected in many" 30 "liver cancer: 132.4" "Region enhanced" "Detected in many" "cerebral cortex: 14.4" "Immune cell enriched" "Detected in many" 20 "neutrophil: 1161.4" "Lineage enriched" "Detected in many" 20 "granulocytes: 1161.4" "Cell line enriched" "Detected in some" 29 "U-87 MG: 29.7" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA074762, CAB075684" Enhanced NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 41: Macrophages - Immune response" "CAB075684: , HPA074762: AB_2732267" "unprognostic (1.91e-1)" "unprognostic (1.92e-1)" "unprognostic (7.30e-2)" "unprognostic (2.67e-1)" "unprognostic (1.24e-2)" "unprognostic (4.15e-2)" "unprognostic (1.36e-3)" "unprognostic (2.28e-2)" "unprognostic (3.82e-2)" "unprognostic (2.03e-1)" "unprognostic (4.80e-3)" "unprognostic (6.98e-2)" "prognostic unfavorable (5.72e-11)" "unprognostic (8.78e-2)" "unprognostic (1.13e-2)" "unprognostic (1.25e-1)" "unprognostic (8.39e-2)" 18.2 0.8 0.8 72.9 0.9 67.5 2.4 0.9 14.4 1.3 0.8 0.9 0.2 1.2 43.4 1.2 7.1 5.3 1.7 3.2 0.5 0.9 702.7 22.2 0.6 0.7 1.0 0.5 1.6 5.6 0.3 6.2 4.0 0.9 0.3 0.4 1.1 0.7 0.5 22.0 0.9 6.4 0.6 42.7 1.5 0.3 6.9 1.8 0.6 7.5 0.8 32.6 0.6 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 29.7 0.1 0.0 0.2 58.4 1.2 0.1 17.5 0.1 0.5 0.1 0.0 1.8 0.1 0.1 0.0 1161.4 0.3 23.0 0.6 0.3 18.9 0.8 0.9 0.9 14.4 3.2 0.5 0.7 1.0 4.0 0.6 6.9 0.8 0.7 0.0 12.2 0.3 2.3 0.4 0.2 0.0 0.0 0.0 0.1 0.0 1.1 5.7 3.1 0.0 0.0 0.3 0.5 0.0 0.0 0.1 2.1 0.3 0.1 0.7 0.0 13.9 2.4 0.2 0.9 1.9 0.0 1.8 7.6 0.0 7.9 313.9 40.8 0.0 0.8 0.0 0.0 28.5 6.2 1.9 0.3 82.1 0.0 0.0 18.9 0.0 1.0 0.5 0.2 0.5 0.0 0.0 0.7 0.2 0.0 0.3 1.5 0.0 0.0 0.5 0.2 0.1 0.0 0.0 0.6 0.8 1.5 0.0 0.0 0.1 ARF6 ENSG00000165527 "ADP ribosylation factor 6" P62330 14 49893082-49897054 "Predicted intracellular proteins, RAS pathway related proteins" "Cell cycle, Cell division, Differentiation, Neurogenesis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 716.1;Suprabasal keratinocytes: 673.3;Urothelial cells: 703.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002778, CAB079914" Approved Supported Cytosol NA NA 310000 "Cluster 44: Non-specific - Transcription" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 2: Karpas-707 - Immune response" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "CAB002778: , CAB079914: AB_2539861" "unprognostic (1.21e-1)" "unprognostic (2.75e-3)" "unprognostic (1.80e-1)" "unprognostic (7.02e-2)" "unprognostic (2.85e-1)" "unprognostic (1.83e-1)" "unprognostic (4.12e-3)" "unprognostic (2.16e-1)" "unprognostic (1.23e-1)" "unprognostic (1.41e-1)" "prognostic unfavorable (3.10e-5)" "unprognostic (1.61e-1)" "unprognostic (1.67e-1)" "unprognostic (8.37e-3)" "unprognostic (1.22e-1)" "unprognostic (2.37e-1)" "unprognostic (1.49e-2)" 32.1 25.3 13.4 43.6 14.2 83.1 32.6 15.2 15.3 35.7 16.3 53.4 46.4 21.7 26.6 108.2 28.3 32.8 18.3 11.8 14.3 29.7 46.1 31.5 62.0 14.7 14.3 15.3 24.7 20.4 12.6 36.3 15.4 32.2 51.0 13.2 36.3 19.2 26.1 66.0 51.2 23.8 15.6 49.6 46.7 15.8 15.9 45.2 21.1 17.1 66.7 46.8 55.7 15.6 141.5 58.2 38.4 44.8 51.5 68.4 78.3 86.5 62.6 60.3 62.2 42.6 96.2 91.3 43.7 72.7 46.3 101.7 43.7 69.3 71.3 181.4 34.9 47.2 30.6 38.3 58.1 87.2 60.7 53.7 81.5 48.9 93.7 72.1 67.6 58.3 45.9 176.9 84.7 101.5 77.7 76.5 42.0 75.9 82.8 59.4 50.1 53.9 157.6 112.9 56.4 37.4 68.9 102.3 89.0 46.5 78.0 70.0 90.0 111.9 57.4 66.7 66.1 94.3 104.4 68.6 40.1 50.9 81.3 34.2 20.7 21.1 34.7 33.0 37.6 33.5 33.7 35.3 23.9 26.6 23.0 29.6 14.7 29.1 31.4 15.8 36.2 23.4 13.4 14.2 15.2 15.3 11.8 14.3 14.7 14.3 15.4 15.6 15.9 15.6 102.9 51.3 29.9 2.9 233.7 599.8 529.1 47.9 231.6 22.9 154.4 80.1 18.5 127.2 47.6 101.2 2.1 152.7 298.8 276.0 158.5 125.4 5.8 95.6 98.5 117.1 99.3 140.1 5.3 80.0 208.1 94.9 115.7 143.7 79.9 40.3 108.5 143.3 168.0 33.7 5.9 167.0 20.3 195.6 716.1 8.3 33.5 184.5 304.1 15.0 204.9 42.2 192.6 6.0 8.9 130.4 161.6 32.7 182.4 443.4 190.8 166.5 30.3 21.6 46.0 68.8 90.7 62.7 48.7 361.4 673.3 202.9 311.0 52.6 182.5 703.8 ARG1 ENSG00000118520 "Arginase 1" P05089 6 131470832-131584332 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Adaptive immunity, Arginine metabolism, Immunity, Innate immunity, Urea cycle" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 1203.5" "Cell type enriched" "Detected in some" 22 "Hepatocytes: 991.4" "Cancer enriched" "Detected in some" 45 "liver cancer: 167.7" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in some" 5 "neutrophil: 44.9" "Lineage enriched" "Detected in many" 5 "granulocytes: 44.9" "Cell line enhanced" "Detected in single" "HL-60: 1.4" "Region enhanced" "Detected in single" "cerebellum: 2.4" "Low region specificity" "Detected in all" "HPA003595, CAB009434, HPA024006, CAB056159, CAB080011" Enhanced NA NA 9500000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 2: Hepatocytes - Metabolism" "CAB009434: AB_2058955, CAB056159: AB_2665582, CAB080011: , HPA003595: AB_1078190, HPA024006: AB_1844987" "unprognostic (2.00e-1)" "unprognostic (2.09e-1)" "unprognostic (2.49e-1)" "unprognostic (1.74e-1)" "unprognostic (9.95e-2)" "unprognostic (7.96e-2)" "unprognostic (7.73e-2)" "unprognostic (1.68e-1)" "unprognostic (1.22e-1)" "unprognostic (1.56e-2)" "unprognostic (7.55e-3)" "unprognostic (8.35e-2)" "unprognostic (1.25e-2)" "unprognostic (2.90e-2)" "unprognostic (2.75e-1)" "unprognostic (1.11e-2)" "unprognostic (1.79e-2)" 2.2 0.2 0.1 0.3 0.2 292.0 4.8 1.0 0.5 0.3 0.2 0.2 0.0 0.1 0.0 2.1 1.9 0.0 0.8 0.3 0.2 0.3 1203.5 6.5 0.3 0.4 0.2 0.2 0.4 0.0 0.2 1.7 0.3 0.3 0.0 0.3 0.9 0.0 0.5 92.8 0.3 0.2 0.1 20.6 0.4 0.1 0.2 1.2 0.5 0.6 0.7 0.2 2.2 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.5 0.0 1.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 1.0 0.1 0.0 0.2 0.7 0.3 44.9 0.0 0.9 0.2 9.3 0.4 0.1 0.2 1.0 0.5 0.3 0.2 0.4 0.2 0.3 0.1 0.2 0.2 0.0 0.0 0.0 0.3 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 17.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.1 0.1 1.5 0.0 43.6 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 23.2 991.4 0.0 0.0 0.1 0.1 0.0 27.6 0.0 0.6 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.1 ARHGAP11A KIAA0013 ENSG00000198826 "Rho GTPase activating protein 11A" Q6P4F7 15 32615144-32639941 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 24.2;lymphoid tissue: 26.1" "Cell type enhanced" "Detected in many" "Erythroid cells: 38.7;Extravillous trophoblasts: 23.7;Granulosa cells: 21.1;Plasma cells: 18.6;Spermatocytes: 24.7;Spermatogonia: 22.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040830, HPA066481" Enhanced Approved Nucleoli,Cytosol No Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol Nucleoli "HPA040830: AB_10805830, HPA066481: " "unprognostic (5.00e-2)" "unprognostic (5.57e-2)" "unprognostic (6.10e-2)" "unprognostic (1.97e-1)" "unprognostic (2.93e-1)" "unprognostic (3.41e-2)" "prognostic unfavorable (2.05e-4)" "prognostic unfavorable (8.69e-4)" "unprognostic (4.87e-2)" "unprognostic (7.71e-2)" "prognostic unfavorable (2.92e-5)" "unprognostic (3.43e-2)" "unprognostic (1.07e-12)" "unprognostic (7.37e-2)" "unprognostic (5.23e-1)" "unprognostic (1.54e-2)" "unprognostic (9.64e-2)" 1.7 0.9 2.0 7.9 2.5 24.2 1.7 2.1 2.1 1.5 1.2 7.5 6.1 1.5 1.0 5.3 0.8 1.7 0.7 1.7 1.9 0.6 1.3 1.7 13.5 2.6 3.0 0.6 2.6 1.2 0.7 4.3 2.6 0.6 8.8 0.5 1.2 0.5 0.9 4.4 7.6 4.8 2.5 2.8 3.6 8.6 2.2 26.1 1.3 0.4 14.3 2.8 1.9 3.0 80.8 69.4 73.1 46.2 5.0 13.0 39.6 78.5 50.2 80.0 63.3 52.2 41.5 43.5 23.7 49.9 91.3 56.9 55.3 43.8 110.9 83.5 27.4 132.6 68.9 33.5 2.0 103.8 55.5 4.3 5.5 61.6 50.9 15.2 61.5 94.4 101.0 112.7 95.3 31.7 58.6 39.7 44.6 71.6 44.5 67.8 141.7 38.2 28.4 41.6 64.7 44.5 72.9 46.2 17.6 37.6 63.6 115.8 35.3 102.5 74.1 42.0 87.2 38.3 63.7 123.7 44.4 129.1 91.8 0.1 0.3 0.8 0.5 0.5 0.2 0.3 1.0 0.9 0.4 0.2 0.4 0.5 0.0 0.1 0.1 0.2 0.8 0.3 2.0 2.5 2.1 2.1 1.7 1.9 2.6 3.0 2.6 2.5 2.2 3.0 0.7 0.0 2.3 0.3 4.6 4.8 1.1 2.4 2.2 0.2 1.3 1.7 0.9 4.3 1.9 1.8 0.0 9.8 2.9 6.2 0.0 0.8 4.7 3.8 2.6 2.0 0.0 38.7 1.0 0.8 23.7 3.5 8.6 2.8 0.0 21.1 1.8 2.1 9.5 0.0 0.6 7.8 0.0 6.5 4.2 5.0 0.6 3.5 0.0 1.0 3.9 0.1 2.1 0.5 1.4 0.5 2.9 0.4 18.6 1.4 1.1 0.4 1.4 1.0 6.6 1.4 3.3 24.7 22.6 10.5 2.3 3.1 5.4 2.0 14.1 2.1 ARL4D ARF4L ENSG00000175906 "ADP ribosylation factor like GTPase 4D" P49703 17 43398993-43401137 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 224.3;Early spermatids: 220.8;Rod photoreceptor cells: 259.6;Squamous epithelial cells: 223.4;Suprabasal keratinocytes: 254.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 32.3;naive B-cell: 36.1" "Lineage enriched" "Detected in all" 4 "B-cells: 36.1" "Cell line enhanced" "Detected in many" "HHSteC: 57.1;hTCEpi: 76.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basal ganglia: 8.7;cerebral cortex: 8.8;hippocampal formation: 5.7;olfactory bulb: 4.2;spinal cord: 5.4" HPA060379 Uncertain Approved "Golgi apparatus,Vesicles" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 77: Retina - Visual perception" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" Vesicles "Golgi apparatus" "HPA060379: AB_2684269" "unprognostic (9.53e-3)" "unprognostic (1.65e-1)" "unprognostic (2.34e-2)" "prognostic favorable (1.16e-5)" "unprognostic (7.71e-2)" "prognostic unfavorable (6.66e-4)" "unprognostic (2.47e-1)" "unprognostic (4.59e-2)" "unprognostic (4.45e-1)" "unprognostic (1.25e-1)" "unprognostic (3.37e-2)" "unprognostic (7.87e-2)" "unprognostic (2.00e-3)" "unprognostic (3.49e-2)" "unprognostic (6.48e-2)" "unprognostic (1.27e-3)" "prognostic unfavorable (9.25e-4)" 21.0 4.3 7.9 2.2 8.7 0.9 7.2 9.1 11.6 29.3 12.6 27.9 2.0 20.2 4.7 82.2 22.1 7.3 12.7 8.1 7.1 30.5 56.4 16.2 1.6 5.6 5.7 9.7 2.2 8.1 21.6 7.7 5.7 11.0 3.5 85.1 16.9 15.2 1.9 44.9 6.0 14.8 5.4 16.7 7.6 32.1 5.7 1.6 38.3 3.4 3.0 28.5 39.5 9.3 8.7 10.9 6.7 5.2 12.5 17.2 3.1 21.0 21.5 14.6 18.8 9.7 37.7 0.1 10.3 22.6 10.0 23.4 4.5 32.0 10.0 1.9 7.5 0.7 8.7 22.5 57.1 2.4 2.1 19.2 76.1 21.3 45.8 13.2 6.3 2.3 1.4 0.4 14.3 0.5 5.4 5.0 7.1 0.8 10.1 9.1 1.5 1.0 24.9 18.8 7.9 5.6 16.5 0.4 15.8 14.4 30.6 8.5 1.3 21.0 6.7 27.2 6.4 2.1 1.1 0.0 25.8 1.9 7.1 0.1 2.8 2.1 5.1 4.3 3.2 32.3 4.2 4.7 8.4 36.1 4.6 5.2 0.0 2.1 1.4 2.5 1.0 4.6 7.9 8.7 9.1 11.6 8.1 7.1 5.6 5.7 5.7 5.4 5.7 9.3 28.8 0.0 1.7 0.7 37.9 224.3 41.4 142.2 132.1 155.5 35.3 60.6 12.7 5.7 49.5 132.4 116.7 39.9 37.4 1.5 76.3 2.3 220.8 55.5 33.3 32.2 11.9 4.0 9.1 1.8 24.1 52.3 5.6 69.6 0.0 20.7 22.9 29.7 8.1 16.8 9.3 5.4 26.4 4.1 77.9 55.3 15.8 16.6 26.6 1.0 1.4 70.1 2.1 2.5 1.3 3.7 0.9 22.6 1.4 9.5 0.3 17.6 7.6 259.6 13.1 11.1 45.1 25.0 9.2 223.4 254.6 105.5 31.7 19.3 4.6 78.1 ARR3 ARRX ENSG00000120500 "Arrestin 3" P36575 X 70268305-70281840 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 170 "retina: 392.2" "Cell type enriched" "Detected in some" 8 "Cone photoreceptor cells: 1538.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 2.2" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA063129 Enhanced Approved "Golgi apparatus" NA NA "Cluster 79: Retina - Phototransduction" "Cluster 2: Karpas-707 - Immune response" "Cluster 9: Photoreceptor cells - Phototransduction" "Golgi apparatus" "HPA063129: AB_2732696" "unprognostic (1.48e-2)" "unprognostic (1.65e-1)" "unprognostic (1.70e-2)" "unprognostic (5.37e-2)" "unprognostic (2.82e-1)" "unprognostic (1.37e-2)" "unprognostic (2.06e-2)" "unprognostic (1.22e-1)" "unprognostic (1.35e-2)" "unprognostic (8.09e-2)" "unprognostic (1.33e-1)" "unprognostic (4.02e-3)" "unprognostic (2.77e-7)" "unprognostic (8.64e-2)" "unprognostic (6.53e-2)" "unprognostic (6.06e-2)" "unprognostic (1.43e-1)" 0.2 0.3 0.1 0.5 0.2 0.5 0.0 0.0 0.1 0.0 0.6 0.3 0.6 0.3 0.0 0.2 0.1 0.4 0.4 0.1 0.1 0.1 0.0 0.2 0.9 0.4 0.3 0.3 0.4 0.0 0.0 0.3 0.3 0.3 0.2 392.2 0.3 0.0 0.3 2.3 0.9 0.0 0.1 0.5 0.4 0.2 0.3 0.0 0.4 0.0 0.0 0.2 0.0 0.2 0.1 0.2 1.2 0.8 0.0 0.0 0.7 0.6 0.0 0.0 0.0 0.2 0.4 0.5 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.5 1.2 0.1 0.4 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 1.3 0.0 0.4 0.1 2.2 0.0 0.2 0.4 0.2 0.3 0.2 0.2 0.4 0.2 0.0 0.0 0.5 0.1 0.3 0.2 0.0 0.0 0.7 0.0 0.1 0.9 0.5 0.7 0.5 0.0 0.5 0.3 0.3 0.5 0.7 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.1 0.1 0.4 0.3 0.3 0.1 0.3 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 46.7 0.0 0.0 0.3 0.0 0.0 0.0 1538.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.5 0.2 0.4 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 68.7 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 172.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ASB2 ASB-2 ENSG00000100628 "Ankyrin repeat and SOCS box containing 2" Q96Q27 14 93934166-93976739 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "skeletal muscle: 522.2;tongue: 157.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 51.1;Early spermatids: 26.4;Late spermatids: 29.9;Skeletal myocytes: 27.6;T-cells: 14.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in many" 7 "eosinophil: 50.8" "Lineage enriched" "Detected in many" 7 "granulocytes: 50.8" "Cell line enhanced" "Detected in some" "Karpas-707: 12.8;RPMI-8226: 12.4;SK-MEL-30: 5.9;U-266/70: 42.1;U-266/84: 8.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA001546 Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 29: U-266 - Adaptive immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "HPA001546: AB_1078224" "unprognostic (5.65e-4)" "unprognostic (8.19e-2)" "unprognostic (1.31e-1)" "prognostic favorable (3.62e-6)" "unprognostic (4.11e-2)" "unprognostic (1.61e-1)" "unprognostic (5.29e-2)" "unprognostic (1.05e-3)" "unprognostic (4.25e-2)" "unprognostic (1.48e-2)" "unprognostic (2.51e-2)" "unprognostic (1.89e-1)" "unprognostic (2.49e-7)" "unprognostic (2.51e-3)" "unprognostic (2.12e-1)" "unprognostic (2.01e-2)" "unprognostic (2.27e-1)" 2.9 0.8 0.8 5.6 2.1 0.5 1.5 0.0 1.9 12.0 0.0 66.5 4.0 31.6 0.3 4.0 26.6 0.5 78.5 0.6 0.0 0.5 0.5 3.0 7.4 0.1 0.0 2.9 0.3 0.2 0.2 0.2 0.3 14.4 0.4 0.0 6.6 0.9 522.2 2.3 18.3 1.6 0.0 4.2 17.2 0.4 0.3 0.4 1.2 157.6 3.2 30.4 8.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.2 0.0 1.3 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.2 0.0 0.4 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 12.8 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.1 0.0 12.4 0.0 0.2 0.1 0.0 0.0 0.0 5.9 0.0 0.0 2.9 0.0 0.0 0.0 0.2 0.0 42.1 8.6 1.7 0.5 2.6 0.5 0.0 0.2 50.8 1.9 2.7 0.3 1.9 1.7 3.8 4.2 0.4 0.2 0.5 0.1 0.0 7.8 0.4 2.3 1.3 0.8 2.1 0.0 1.9 0.6 0.0 0.1 0.0 0.3 0.0 0.3 0.1 0.2 0.0 0.0 0.3 3.3 0.4 0.1 8.4 0.0 0.2 0.2 0.9 51.1 0.0 2.9 0.0 0.0 0.1 3.0 0.0 0.0 1.4 26.4 1.7 0.3 0.5 0.0 2.7 4.7 0.0 0.5 1.9 1.1 2.5 0.0 0.0 0.0 0.0 0.6 0.0 1.9 0.0 0.0 0.0 0.3 29.9 0.3 5.3 1.8 1.9 5.8 0.8 2.1 0.0 0.7 0.2 0.0 0.4 10.7 0.1 0.0 0.0 0.4 1.1 0.0 27.6 5.0 0.8 8.4 0.1 0.1 2.9 14.5 0.1 0.1 0.3 ASPHD2 FLJ39838 ENSG00000128203 "Aspartate beta-hydroxylase domain containing 2" Q6ICH7 22 26429260-26445015 "Predicted membrane proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.9;skin 1: 11.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 24.8;Early spermatids: 25.3;Late spermatids: 25.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 5.3" "Group enriched" "Detected in many" 4 "dendritic cells: 2.4;monocytes: 5.3" "Cell line enhanced" "Detected in many" "Karpas-707: 21.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000820 Uncertain NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 2: Karpas-707 - Immune response" "Cluster 34: Spermatids - Unknown function" "HPA000820: AB_1078231" "unprognostic (1.12e-1)" "unprognostic (1.64e-1)" "unprognostic (1.07e-2)" "unprognostic (2.71e-1)" "unprognostic (1.94e-1)" "unprognostic (9.07e-2)" "unprognostic (2.02e-2)" "unprognostic (1.86e-1)" "unprognostic (1.24e-2)" "unprognostic (8.98e-2)" "unprognostic (1.73e-1)" "unprognostic (1.79e-1)" "prognostic unfavorable (4.06e-5)" "unprognostic (6.55e-2)" "unprognostic (9.26e-2)" "unprognostic (1.09e-2)" "unprognostic (1.11e-2)" 0.7 0.6 8.0 2.5 16.9 1.5 0.6 10.4 9.0 1.5 0.6 2.0 1.2 1.2 6.2 1.5 0.5 1.1 0.4 8.3 7.0 6.1 0.3 0.9 4.4 4.1 4.3 0.6 0.5 1.7 6.6 1.1 5.5 1.1 2.0 5.6 1.0 0.7 0.4 11.1 1.6 0.7 3.1 2.8 8.2 1.9 6.4 1.3 2.0 0.1 3.3 2.3 1.1 5.8 1.6 0.9 4.1 6.5 0.6 0.3 2.2 2.1 4.5 4.3 6.2 0.0 0.4 1.4 0.5 2.0 4.3 1.9 4.5 7.2 2.3 9.7 6.1 0.3 0.0 0.3 4.1 2.4 1.1 0.7 3.4 2.2 3.0 4.7 4.6 3.6 1.7 21.9 1.3 0.4 1.8 1.0 4.0 8.5 0.9 12.2 2.3 3.7 6.0 0.6 11.0 4.8 2.1 0.3 2.4 2.2 0.2 3.5 4.3 2.7 13.4 0.6 4.4 6.3 1.7 2.8 4.1 8.6 1.8 0.0 1.2 0.5 0.3 3.3 0.9 0.9 0.7 0.7 2.1 0.9 0.4 0.4 0.3 0.0 5.3 2.4 0.4 0.4 8.0 16.9 10.4 9.0 8.3 7.0 4.1 4.3 5.5 3.1 6.4 5.8 0.3 0.0 1.1 4.2 5.1 1.8 1.4 2.1 0.0 24.8 0.9 0.9 0.6 1.5 0.9 0.0 10.4 0.3 6.8 3.3 0.0 1.2 25.3 0.7 0.5 1.1 0.0 0.0 14.1 0.7 13.2 1.3 8.2 1.5 0.0 0.9 1.1 0.1 1.5 6.7 9.7 4.3 2.0 2.8 5.7 25.1 0.9 4.1 1.8 1.0 5.3 2.4 2.1 4.5 1.1 5.9 0.8 0.7 12.1 4.6 0.1 0.7 0.8 11.3 0.0 0.4 0.7 1.1 3.3 0.6 1.1 1.1 2.8 0.4 2.0 4.2 ASPM "ASP, Calmbp1, FLJ10517, FLJ10549, MCPH5" ENSG00000066279 "Assembly factor for spindle microtubules" Q8IZT6 1 197084121-197146694 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Calmodulin-binding "Cancer-related genes, Disease variant, Mental retardation, Primary microcephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 10.1;lymphoid tissue: 17.0" "Cell type enhanced" "Detected in many" "Erythroid cells: 99.5;Granulosa cells: 121.1;Plasma cells: 44.8;Spermatocytes: 43.8;Spermatogonia: 44.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" CAB017816 Approved "Plasma membrane,Cytosol" NA Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Cytosol" "CAB017816: " "unprognostic (3.24e-1)" "unprognostic (1.56e-1)" "unprognostic (2.81e-2)" "prognostic unfavorable (1.97e-4)" "unprognostic (3.67e-1)" "unprognostic (3.47e-2)" "prognostic unfavorable (1.25e-4)" "prognostic unfavorable (2.41e-4)" "unprognostic (4.67e-3)" "unprognostic (9.29e-2)" "prognostic unfavorable (2.40e-4)" "unprognostic (1.03e-1)" "unprognostic (0.00e+0)" "unprognostic (7.31e-3)" "unprognostic (1.23e-1)" "unprognostic (4.94e-2)" "unprognostic (3.66e-2)" 0.2 0.1 0.0 3.0 0.0 10.1 0.4 0.0 0.1 0.2 0.0 1.6 2.1 0.3 0.0 1.5 0.0 0.3 0.1 0.0 0.0 0.0 0.6 0.3 5.3 0.0 0.0 0.1 0.0 0.0 0.0 1.5 0.0 0.1 1.9 0.0 0.2 0.0 0.0 2.7 1.9 0.7 0.0 0.9 1.1 3.2 0.1 17.0 0.1 0.0 5.1 0.6 0.4 0.2 44.6 22.9 39.1 23.2 1.9 5.5 14.7 35.1 23.2 32.6 25.6 16.7 31.1 45.4 12.5 27.5 13.8 40.2 33.6 12.1 39.1 41.8 25.4 33.1 56.1 12.8 0.4 51.9 20.5 0.6 1.0 26.1 15.2 7.3 31.5 32.9 41.8 50.7 29.0 16.0 40.6 10.3 17.8 24.8 6.4 30.2 55.5 31.7 7.4 11.4 20.4 29.5 50.6 20.6 9.5 20.8 26.9 12.7 28.9 20.9 20.0 34.9 61.2 13.9 21.6 26.8 14.9 11.0 42.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.6 0.0 1.1 1.3 5.8 6.1 1.5 4.0 2.2 0.1 2.4 2.4 1.1 0.0 1.3 1.8 0.0 20.0 7.8 7.7 0.0 0.3 3.9 2.9 6.2 4.3 0.0 99.5 2.0 0.0 14.8 9.8 13.3 8.1 1.3 121.1 6.4 2.2 11.6 0.0 4.8 6.8 4.1 6.4 2.4 4.5 0.6 6.4 0.0 0.0 0.9 0.7 4.1 0.0 1.0 0.5 0.2 1.5 44.8 2.0 0.4 0.4 0.8 0.3 0.0 0.6 7.0 43.8 44.7 27.1 3.4 3.7 9.1 5.7 16.9 2.1 ASPRV1 "FLJ25084, SASPase, Taps" ENSG00000244617 "Aspartic peptidase retroviral like 1" Q53RT3 2 69960089-69962265 "Human disease related genes, Plasma proteins, Predicted membrane proteins" "Aspartyl protease, Hydrolase, Protease" "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 25 "skin 1: 424.0" "Cell type enhanced" "Detected in some" "NK-cells: 3.1;Oligodendrocytes: 4.2;Spermatogonia: 3.3;Suprabasal keratinocytes: 10.7" "Group enriched" "Detected in many" 8 "head and neck cancer: 23.1;melanoma: 35.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "neutrophil: 8.7" "Lineage enriched" "Detected in single" 10 "granulocytes: 8.7" "Cell line enhanced" "Detected in some" "NB-4: 2.9;REH: 4.9" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA034809, HPA034810" Enhanced Approved Cytosol NA NA 150000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 61: Skin - Cornification" "Cluster 14: REH - Unknown function" "Cluster 43: Cardiomyocytes - Nuclear processes" Cytosol "HPA034809: AB_2674343, HPA034810: AB_10601456" "unprognostic (4.75e-4)" "unprognostic (1.90e-3)" "unprognostic (2.34e-2)" "unprognostic (3.34e-2)" "unprognostic (2.65e-1)" "unprognostic (1.17e-2)" "unprognostic (1.93e-3)" "unprognostic (1.51e-1)" "unprognostic (1.36e-1)" "unprognostic (2.51e-1)" "unprognostic (4.19e-3)" "unprognostic (1.27e-1)" "unprognostic (4.01e-2)" "unprognostic (3.00e-1)" "unprognostic (1.74e-1)" "unprognostic (4.84e-2)" "unprognostic (2.43e-2)" 2.6 2.1 5.8 0.9 7.3 0.9 17.1 6.1 6.6 3.1 3.0 1.7 1.6 2.5 2.6 0.9 2.3 1.1 1.8 5.3 6.0 2.2 1.9 1.7 1.0 7.2 6.7 4.8 0.7 0.2 4.0 0.9 6.5 2.2 0.6 1.5 1.3 1.3 4.4 424.0 1.7 1.2 6.0 3.9 1.2 3.6 6.5 2.1 1.3 2.1 1.0 1.5 4.5 9.3 0.0 0.3 0.9 1.9 1.2 0.4 0.2 0.2 0.4 0.2 0.1 0.6 0.0 0.7 0.1 0.2 0.2 0.2 0.8 0.1 0.2 1.3 2.5 1.5 0.2 0.6 0.4 1.3 1.0 0.5 0.4 0.2 0.4 0.3 0.2 1.6 0.5 1.9 0.2 0.3 1.1 2.9 1.0 0.2 0.2 4.9 0.5 0.3 0.0 0.0 1.0 0.2 0.1 0.7 0.8 0.2 0.0 0.5 0.1 0.0 0.9 0.0 0.2 2.0 1.3 1.4 0.1 0.9 1.0 0.0 0.1 1.5 0.5 0.1 0.5 0.0 0.2 0.4 0.0 0.1 0.1 0.4 8.7 0.3 0.0 0.8 0.7 0.4 5.8 7.3 6.1 6.6 5.3 6.0 7.2 6.7 6.5 6.0 6.5 9.3 1.1 0.0 0.0 1.3 0.0 0.4 0.1 0.2 0.0 1.1 0.5 0.9 2.6 0.0 0.1 1.8 0.0 0.3 0.1 0.5 0.0 0.1 0.1 0.4 0.5 0.8 0.0 0.0 1.0 0.2 0.0 0.7 0.0 0.4 0.0 1.1 1.4 0.1 0.2 0.0 1.5 0.9 0.0 0.3 0.6 0.5 0.9 0.3 0.0 1.0 0.2 1.2 3.1 1.5 4.2 0.3 0.0 0.7 0.1 0.2 1.1 0.9 0.2 1.6 0.0 0.7 1.1 1.4 3.3 0.0 10.7 0.4 0.2 0.5 0.2 0.1 ATP1B1 ATP1B ENSG00000143153 "ATPase Na+/K+ transporting subunit beta 1" P05026 1 169105697-169132722 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 1337.8" "Cell type enhanced" "Detected in all" "Collecting duct cells: 1723.3;Proximal tubular cells: 1070.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 13.2" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "OE19: 919.7;RPTEC TERT1: 513.0;SH-SY5Y: 382.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012911 Enhanced NA NA 2100000 "Cluster 27: Non-specific - Gene expression" "Cluster 7: Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA012911: AB_1845173" "unprognostic (4.20e-2)" "unprognostic (3.08e-1)" "unprognostic (1.13e-1)" "unprognostic (1.85e-2)" "unprognostic (1.95e-1)" "unprognostic (5.34e-2)" "unprognostic (2.22e-1)" "unprognostic (1.69e-1)" "unprognostic (3.24e-1)" "unprognostic (6.80e-2)" "unprognostic (1.66e-1)" "unprognostic (1.35e-1)" "prognostic favorable (7.08e-7)" "unprognostic (1.11e-1)" "unprognostic (5.48e-2)" "unprognostic (1.97e-3)" "unprognostic (9.39e-2)" 12.4 146.9 197.7 48.0 216.2 4.4 79.4 370.0 451.1 37.5 369.3 246.1 336.6 108.8 64.3 159.8 48.8 178.7 160.5 326.4 332.1 1337.8 180.1 92.6 8.5 558.7 264.3 58.1 178.5 732.7 79.8 44.1 540.2 48.6 201.1 99.3 314.1 72.6 342.9 67.0 284.4 96.6 248.8 52.6 402.1 46.3 375.1 19.2 330.2 337.8 84.0 101.2 52.1 382.2 89.7 215.8 73.3 56.3 15.9 3.3 23.8 45.3 33.1 41.7 43.3 276.8 183.5 0.1 158.3 35.1 50.8 102.4 38.1 83.2 45.1 1.1 16.6 5.7 152.6 138.9 26.6 4.0 7.5 9.1 21.1 31.8 42.5 79.7 40.5 6.6 1.3 1.4 52.6 38.0 7.9 16.0 28.1 919.7 47.4 1.3 89.3 15.6 513.0 118.6 54.3 382.5 263.1 271.3 12.5 85.4 55.7 9.8 92.0 35.2 90.4 60.9 159.3 4.8 6.8 2.0 42.0 13.9 47.9 13.2 1.0 0.2 2.7 3.2 1.5 1.5 3.3 1.3 9.3 0.2 1.0 1.1 0.3 6.2 1.1 0.4 10.1 1.4 197.7 216.2 370.0 451.1 326.4 332.1 558.7 264.3 540.2 248.8 375.1 382.2 14.4 240.4 251.5 79.0 18.4 52.5 156.5 490.4 153.1 86.9 274.2 166.5 147.3 664.8 425.7 1723.3 14.6 4.8 21.0 817.1 923.4 629.9 3.8 199.6 11.6 18.6 160.9 6.9 344.7 591.9 9.0 78.7 353.7 190.6 23.4 89.0 45.7 273.3 385.3 580.5 602.3 296.7 370.2 99.5 676.1 9.0 89.8 101.5 247.3 81.5 27.1 23.4 1.0 94.5 514.7 377.9 666.4 149.0 16.9 84.4 646.8 1070.2 332.5 64.9 6.6 93.6 32.5 10.6 66.9 142.8 31.7 9.9 48.2 111.8 436.0 322.8 ATP2A3 SERCA3 ENSG00000074370 "ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3" Q93084 17 3923870-3964464 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 101.5;salivary gland: 185.3" "Cell type enhanced" "Detected in many" "B-cells: 82.5;Distal enterocytes: 120.7;Enteroendocrine cells: 97.8;Gastric mucus-secreting cells: 153.4;Intestinal goblet cells: 128.4;Plasma cells: 96.0;Undifferentiated cells: 65.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 186.8;HMC-1: 266.1;JURKAT: 152.1;MOLT-4: 253.2;SK-BR-3: 195.2" "Region enriched" "Detected in all" 15 "cerebellum: 67.2" "Low region specificity" "Detected in all" "HPA007180, CAB010882" Approved NA NA 5400000 "Cluster 52: Eosinophils - Transcription" "Cluster 25: Pancreas - Digestion" "Cluster 3: HMC-1 - Innate immune response" "Cluster 27: Mucus-secreting cells - Mucin production" "CAB010882: AB_258368, HPA007180: AB_1845177" "unprognostic (4.14e-2)" "prognostic favorable (4.69e-5)" "unprognostic (1.21e-2)" "unprognostic (3.68e-2)" "unprognostic (1.02e-2)" "prognostic favorable (2.51e-4)" "unprognostic (8.83e-3)" "unprognostic (2.30e-1)" "unprognostic (8.29e-2)" "unprognostic (3.67e-3)" "unprognostic (3.95e-3)" "unprognostic (1.73e-1)" "unprognostic (1.45e-3)" "unprognostic (1.60e-1)" "unprognostic (3.25e-2)" "unprognostic (1.54e-1)" "unprognostic (1.97e-3)" 6.8 13.7 6.8 62.2 8.7 98.3 7.7 20.0 6.1 6.0 15.3 55.0 30.7 9.1 1.6 9.7 6.1 13.7 8.0 3.0 4.5 11.4 4.6 22.4 101.5 2.3 12.8 3.1 64.0 2.1 2.5 2.8 3.9 20.3 33.0 0.2 185.3 19.6 3.3 28.2 75.3 6.3 2.0 98.2 92.8 2.1 11.6 97.5 11.7 3.3 58.7 17.0 7.2 2.3 0.3 7.6 0.3 6.8 0.0 0.0 0.3 0.4 0.9 0.2 0.6 2.5 1.7 186.8 11.0 0.6 0.1 0.8 3.1 0.0 0.0 23.5 2.1 98.0 6.0 0.1 1.7 108.0 266.1 0.2 0.0 0.7 0.0 0.1 0.3 152.1 20.1 117.1 0.1 116.8 253.2 115.5 1.2 53.1 1.6 27.5 0.2 43.3 0.0 3.3 11.5 3.4 1.5 195.2 0.2 1.1 12.2 26.3 0.5 0.0 2.1 0.4 0.1 43.4 14.2 66.0 2.5 75.6 0.1 16.0 1.4 33.7 10.8 0.9 8.3 9.8 6.7 10.3 1.6 11.4 4.8 6.0 13.1 3.8 0.5 15.8 6.4 6.7 6.8 8.7 20.0 6.1 3.0 4.5 2.3 12.8 3.9 2.0 11.6 2.3 7.1 0.0 1.9 0.7 82.5 0.9 0.4 0.7 1.2 0.0 4.7 1.7 3.8 2.8 2.7 23.9 0.0 0.2 59.2 120.7 0.0 1.3 0.1 0.3 0.4 7.8 97.8 22.5 0.5 12.1 0.3 1.9 153.4 0.3 33.0 0.2 8.9 1.0 2.8 0.0 0.6 128.4 36.7 3.1 2.5 0.2 0.0 17.8 12.4 5.6 5.0 0.2 28.8 0.0 0.3 25.2 50.3 0.7 96.0 4.2 14.0 0.4 2.7 0.2 0.0 1.0 3.4 0.0 1.5 0.4 0.3 0.0 38.4 0.4 65.6 4.6 ATP6V0A4 "a4, ATP6N1B, ATP6N2, RDRTA2, RTA1C, RTADR, Stv1, Vph1, VPP2" ENSG00000105929 "ATPase H+ transporting V0 subunit a4" Q9HBG4 7 138706294-138799560 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "kidney: 63.6;salivary gland: 78.4" "Cell type enhanced" "Detected in some" "Collecting duct cells: 16.5;Cytotrophoblasts: 13.4;Distal tubular cells: 31.3;Ionocytes: 57.0" "Cancer enriched" "Detected in many" 8 "renal cancer: 25.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 11 "SK-BR-3: 55.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA018029, HPA064555" Enhanced Uncertain Cytosol NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol "HPA018029: AB_1845190, HPA064555: AB_2685284" "unprognostic (1.99e-2)" "unprognostic (8.60e-3)" "unprognostic (1.12e-2)" "unprognostic (3.10e-2)" "unprognostic (1.43e-1)" "unprognostic (6.53e-2)" "unprognostic (4.63e-2)" "unprognostic (4.28e-1)" "unprognostic (1.35e-1)" "unprognostic (9.79e-3)" "unprognostic (1.73e-1)" "prognostic favorable (1.32e-6)" "unprognostic (4.35e-1)" "unprognostic (1.56e-1)" "unprognostic (1.02e-1)" "unprognostic (1.10e-2)" 0.2 0.0 0.3 0.0 0.4 0.0 4.7 0.1 0.5 3.7 3.1 0.0 0.1 0.1 1.2 4.9 0.0 0.0 0.0 0.6 0.2 63.6 0.0 0.4 0.0 0.3 0.2 0.0 0.1 1.6 0.1 2.5 0.2 0.9 0.0 0.0 78.4 1.5 0.0 10.2 0.0 0.0 0.2 0.0 0.1 0.2 0.3 0.4 0.0 0.0 3.7 0.1 0.2 0.3 0.2 0.5 0.0 0.0 0.0 0.0 0.5 0.8 0.1 0.6 0.6 1.8 0.0 0.0 0.5 0.2 0.1 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.7 5.0 1.9 0.0 0.1 0.0 0.1 0.1 0.6 0.0 4.5 0.2 0.0 0.0 0.1 55.7 1.9 2.9 0.1 0.0 0.2 0.6 1.3 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.1 0.5 0.6 0.2 0.3 0.2 0.2 0.2 0.3 0.3 0.0 0.0 1.1 0.3 0.0 0.0 1.1 0.9 0.0 0.0 2.5 1.4 0.5 0.0 1.7 16.5 2.1 13.4 0.3 0.0 31.3 0.0 2.2 0.9 0.1 0.1 0.0 0.0 1.4 0.0 0.7 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.7 0.0 1.2 0.0 57.0 0.0 0.0 2.8 0.3 0.0 7.2 1.0 0.0 0.0 0.0 6.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.3 4.4 0.1 0.0 0.0 0.1 0.6 0.7 0.0 0.1 5.1 0.2 0.0 0.0 1.3 ATP6V1B1 "ATP6B1, RTA1B, VATB, Vma2, VPP3" ENSG00000116039 "ATPase H+ transporting V1 subunit B1" P15313 2 70935900-70965431 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" Hydrolase "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "kidney: 127.4;salivary gland: 139.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 197.3;Distal tubular cells: 49.0;Ionocytes: 321.4;Syncytiotrophoblasts: 64.9" "Group enriched" "Detected in many" 5 "ovarian cancer: 94.7;renal cancer: 23.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "BEWO: 21.6;HaCaT: 20.3;SK-BR-3: 49.2" "Not detected" "Not detected" "Not detected" "Not detected" "CAB009523, HPA031847" Enhanced Approved "Nucleoplasm,Nuclear membrane" No NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Nuclear membrane" "CAB009523: AB_677577, HPA031847: AB_2674072" "unprognostic (2.28e-2)" "unprognostic (6.02e-2)" "unprognostic (2.20e-5)" "unprognostic (1.15e-2)" "unprognostic (3.96e-1)" "unprognostic (1.31e-1)" "unprognostic (2.22e-2)" "unprognostic (2.17e-1)" "unprognostic (1.19e-2)" "unprognostic (1.48e-1)" "unprognostic (2.94e-2)" "unprognostic (1.40e-1)" "unprognostic (1.33e-3)" "unprognostic (1.03e-1)" "unprognostic (2.70e-1)" "unprognostic (3.63e-5)" "unprognostic (1.97e-2)" 2.2 0.5 0.5 0.2 0.3 0.0 11.8 0.7 0.9 31.1 0.0 0.6 0.5 1.4 1.2 1.6 12.8 0.2 1.1 0.2 0.0 127.4 0.2 1.7 0.5 0.1 0.0 1.2 3.3 0.8 4.2 17.9 0.1 2.0 0.1 3.9 139.8 1.4 0.5 32.5 0.6 0.8 0.0 0.0 0.3 0.3 0.0 0.1 0.3 0.2 0.0 0.6 0.8 0.3 0.4 0.3 0.6 1.3 2.6 3.1 21.6 0.4 0.2 0.0 0.0 0.1 2.0 0.1 0.2 1.2 0.0 20.3 0.7 0.0 0.0 0.5 0.6 0.0 0.3 0.3 0.0 0.0 0.0 1.5 0.1 0.0 0.3 3.1 0.0 0.1 0.0 0.0 0.2 1.2 0.1 0.3 0.0 0.0 0.0 0.1 0.8 0.2 0.4 0.2 0.5 1.5 0.7 49.2 0.1 2.7 0.6 0.0 0.4 0.6 0.2 0.9 0.5 0.0 0.0 0.0 1.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.3 0.7 0.9 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.7 3.2 0.0 0.3 0.0 0.1 1.3 1.7 0.0 0.9 5.6 3.7 0.4 0.0 13.9 0.0 8.4 197.3 0.1 0.6 49.0 0.1 1.5 0.0 0.1 1.1 0.0 0.0 1.0 0.6 38.3 3.8 0.0 0.1 0.0 0.0 0.0 0.1 11.7 1.7 0.4 0.0 321.4 0.0 0.3 0.1 0.0 0.1 30.2 0.0 0.0 0.5 1.0 1.0 0.1 0.4 0.0 1.2 0.0 0.6 0.3 0.2 2.6 3.8 0.0 1.1 1.0 0.4 1.2 0.0 0.4 64.9 0.1 0.1 0.1 0.6 AURKA "AIK, ARK1, AurA, BTAK, PPP1R47, STK15, STK6, STK7" ENSG00000087586 "Aurora kinase A" O14965 20 56369389-56392337 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Cilium biogenesis/degradation, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 22.1;testis: 30.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 81.6;Extravillous trophoblasts: 67.1;granulocytes: 54.1;Spermatocytes: 168.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB001454, HPA002636" Enhanced Approved "Nucleoplasm,Mitotic spindle,Centrosome,Cytosol" Yes Yes "Cluster 7: Monocytes - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Centrosome" "Mitotic spindle, Cytosol" "CAB001454: AB_563420, HPA002636: AB_1845217" "unprognostic (7.73e-2)" "unprognostic (2.46e-2)" "unprognostic (2.76e-2)" "prognostic unfavorable (9.40e-5)" "unprognostic (1.92e-1)" "unprognostic (2.11e-2)" "prognostic unfavorable (1.49e-4)" "unprognostic (4.69e-3)" "unprognostic (2.42e-1)" "unprognostic (6.88e-2)" "prognostic unfavorable (6.13e-4)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.47e-8)" "unprognostic (1.67e-1)" "unprognostic (6.83e-2)" "unprognostic (9.00e-2)" "unprognostic (5.14e-2)" 1.3 2.3 1.3 10.4 1.6 15.3 2.2 2.4 1.4 1.4 0.6 10.8 11.7 1.5 0.8 7.5 1.2 2.0 5.3 0.8 1.0 2.3 5.0 2.2 20.9 1.7 1.2 8.4 2.0 1.8 0.6 8.1 1.4 1.1 12.9 3.0 1.9 1.3 8.7 3.5 9.3 4.9 1.3 5.2 4.9 30.8 1.6 20.2 1.4 8.2 22.1 2.9 2.6 1.3 179.9 127.2 84.5 61.2 4.9 10.8 106.3 145.2 66.8 339.7 142.9 361.4 124.8 58.4 96.2 59.2 176.2 142.2 152.4 96.4 360.0 52.4 57.5 102.6 128.9 229.8 2.8 140.4 140.4 5.1 10.1 117.3 104.5 26.7 80.7 93.2 121.8 45.3 146.9 182.1 85.3 108.9 78.3 145.6 129.8 62.9 163.4 65.9 56.0 46.8 73.9 39.6 200.5 228.8 94.2 77.3 137.9 86.1 47.1 149.7 145.3 83.0 208.6 62.3 78.9 100.5 80.5 80.9 127.0 0.2 3.5 4.3 1.2 5.9 1.8 2.5 2.0 1.1 3.7 0.8 0.9 0.9 2.3 1.4 3.4 0.8 4.7 1.7 1.3 1.6 2.4 1.4 0.8 1.0 1.7 1.2 1.4 1.3 1.6 1.3 2.5 0.0 2.8 0.3 7.4 1.1 1.2 5.6 0.6 1.0 4.3 6.2 5.6 1.5 2.3 3.7 2.1 34.5 8.3 8.3 1.9 4.0 33.9 2.0 2.3 3.1 6.0 81.6 1.1 4.9 67.1 7.0 13.7 3.4 54.1 12.3 3.6 2.6 17.5 1.7 1.5 10.8 2.0 3.5 7.6 16.3 1.5 11.7 0.0 1.0 12.0 3.7 3.1 1.0 2.0 5.2 2.8 0.4 10.1 2.0 5.1 4.2 1.5 2.7 6.6 2.2 7.7 168.2 30.8 8.3 1.1 8.2 8.0 8.7 15.5 1.5 AURKB "Aik2, AIM-1, ARK2, AurB, IPL1, PPP1R48, STK12, STK5" ENSG00000178999 "Aurora kinase B" Q96GD4 17 8204733-8210600 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 44.1;lymphoid tissue: 60.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 40.5;Erythroid cells: 59.3;Extravillous trophoblasts: 89.1;Granulosa cells: 24.7;Hofbauer cells: 29.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "T-reg: 7.9" "Group enriched" "Detected in many" 6 "B-cells: 2.5;T-cells: 7.9" "Low cell line specificity" "Detected in many" "Group enriched" "Detected in some" 5 "basal ganglia: 1.3;white matter: 4.0" "Low region specificity" "Detected in all" "CAB005862, HPA037708" Enhanced Enhanced Nucleoplasm,Midbody Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Midbody "CAB005862: AB_449204, HPA037708: AB_2675623" "unprognostic (4.76e-2)" "unprognostic (3.61e-3)" "unprognostic (2.25e-1)" "unprognostic (3.14e-2)" "unprognostic (2.27e-1)" "unprognostic (6.05e-2)" "prognostic unfavorable (1.24e-4)" "unprognostic (1.99e-3)" "unprognostic (9.41e-3)" "unprognostic (3.47e-2)" "unprognostic (4.61e-3)" "unprognostic (1.01e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (7.77e-2)" "unprognostic (2.93e-1)" "unprognostic (6.76e-2)" "unprognostic (3.77e-1)" 1.1 1.2 0.1 14.2 0.2 44.1 1.7 0.2 0.2 3.0 0.1 11.1 12.1 1.6 0.4 18.6 0.6 1.5 0.7 0.1 0.2 0.9 2.0 2.5 36.7 0.1 0.3 0.5 0.6 0.3 0.2 8.2 0.3 0.8 11.0 0.0 2.7 0.3 5.5 9.3 11.6 3.2 0.0 12.0 4.6 1.2 0.4 60.1 0.6 0.0 36.6 3.5 5.9 0.2 196.5 130.9 191.1 93.0 4.2 6.5 73.4 91.7 49.5 186.2 170.6 171.5 57.4 193.3 46.2 37.0 77.0 139.8 140.1 62.6 153.7 84.9 231.3 115.7 78.3 146.1 0.7 62.2 109.2 3.5 2.9 109.4 67.7 18.5 86.5 123.6 73.3 73.4 82.9 92.9 225.1 87.4 119.6 63.9 57.6 149.8 176.1 80.5 41.2 38.2 41.2 59.1 81.7 36.5 61.2 56.5 63.5 41.4 33.9 74.3 75.6 67.6 243.3 53.2 37.7 147.9 35.7 92.9 153.4 0.0 0.4 0.6 0.5 0.3 0.1 1.1 1.3 2.1 0.5 2.5 0.1 0.7 0.9 0.3 0.2 0.2 7.9 0.9 0.1 0.2 0.2 0.2 0.1 0.2 0.1 0.3 0.3 0.0 0.4 0.2 0.3 0.0 0.5 0.0 7.6 4.5 1.8 6.1 0.6 0.0 1.8 2.2 1.4 0.0 2.6 0.0 0.0 40.5 1.8 13.2 0.0 0.4 0.1 0.5 1.6 3.1 0.0 59.3 0.0 0.0 89.1 5.7 6.1 2.1 4.5 24.7 6.1 0.7 29.4 0.0 0.0 10.8 0.0 5.7 7.3 0.2 0.6 5.1 1.8 0.0 0.9 0.0 3.1 0.0 0.1 0.3 2.8 0.0 15.4 1.2 1.5 0.1 0.2 0.0 0.0 0.1 4.8 1.6 7.2 11.8 2.4 9.0 4.3 1.0 22.0 2.8 AWAT1 DGAT2L3 ENSG00000204195 "Acyl-CoA wax alcohol acyltransferase 1" Q58HT5 X 70234655-70240659 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "skin 1: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA063412 Enhanced NA NA "Cluster 61: Skin - Cornification" "HPA063412: AB_2685009" "unprognostic (1.12e-1)" "unprognostic (1.78e-1)" "unprognostic (1.96e-2)" "unprognostic (4.90e-2)" "unprognostic (2.08e-1)" "unprognostic (6.78e-2)" 0.0 0.0 0.1 0.0 0.1 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AWAT2 "DGAT2L4, MFAT" ENSG00000147160 "Acyl-CoA wax alcohol acyltransferase 2" Q6E213 X 70040542-70049938 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "skin 1: 11.2" "Cell type enriched" "Detected in some" 6 "Spermatocytes: 8.3" "Cancer enriched" "Detected in single" 7 "testis cancer: 0.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA062748 Approved NA NA "Cluster 61: Skin - Cornification" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA062748: AB_2684862" "unprognostic (3.41e-2)" "unprognostic (1.06e-1)" "unprognostic (2.99e-2)" "unprognostic (4.11e-2)" "unprognostic (1.11e-1)" "unprognostic (8.60e-2)" "unprognostic (4.55e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 11.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.2 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 8.3 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 AXDND1 "C1orf125, FLJ32940" ENSG00000162779 "Axonemal dynein light chain domain containing 1" Q5T1B0 1 179365720-179554735 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 33 "testis: 15.7" "Group enriched" "Detected in some" 4 "Early spermatids: 226.5;Late spermatids: 247.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA071114 Enhanced NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA071114: AB_2686345" "unprognostic (1.67e-2)" "unprognostic (8.37e-2)" "unprognostic (2.81e-2)" "unprognostic (1.05e-1)" "unprognostic (3.34e-1)" "unprognostic (1.73e-1)" "unprognostic (3.78e-4)" "unprognostic (2.62e-1)" "unprognostic (1.75e-1)" "unprognostic (6.99e-3)" "unprognostic (2.09e-2)" "unprognostic (1.31e-1)" "unprognostic (5.17e-3)" "unprognostic (1.92e-1)" "unprognostic (5.48e-2)" "unprognostic (5.04e-2)" "unprognostic (2.25e-1)" 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.2 0.0 0.0 0.4 0.0 0.2 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.2 0.4 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.2 15.7 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.2 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.2 0.4 0.2 0.3 0.2 0.2 0.1 0.0 0.5 8.8 0.3 0.0 0.1 0.1 0.0 0.3 0.1 0.3 0.8 0.0 0.8 0.0 2.1 0.1 0.1 16.3 0.0 0.2 226.5 3.1 0.3 0.2 0.0 0.0 3.1 0.2 0.3 0.1 31.6 0.3 0.0 0.2 0.0 0.0 0.1 0.0 3.2 1.5 0.0 0.0 0.0 247.2 1.5 0.5 0.0 1.0 0.0 0.6 0.0 2.0 2.5 0.6 3.8 1.9 0.1 0.1 2.0 0.1 3.2 0.7 0.0 0.0 0.2 50.2 4.3 0.0 0.0 0.1 0.2 0.6 6.1 0.2 B3GNT4 "B3GN-T4, beta3Gn-T4" ENSG00000176383 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4" Q9C0J1 12 122203681-122208952 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.9;skin 1: 3.1" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 3.3;Excitatory neurons: 3.2;Proximal tubular cells: 9.7;Spermatogonia: 2.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 5.1;hTCEpi: 4.0;T-47d: 4.2;U-266/84: 3.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA055261 Uncertain Approved Nucleoli,Mitochondria NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 44: HDLM-2 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria Nucleoli "HPA055261: AB_2682765" "unprognostic (1.67e-1)" "unprognostic (1.66e-1)" "unprognostic (1.27e-1)" "unprognostic (2.36e-1)" "unprognostic (1.10e-2)" "unprognostic (2.60e-2)" "unprognostic (1.32e-3)" "unprognostic (1.98e-1)" "unprognostic (3.44e-2)" "unprognostic (1.21e-1)" "unprognostic (3.82e-2)" "unprognostic (3.69e-1)" "prognostic unfavorable (3.52e-6)" "unprognostic (1.24e-1)" "unprognostic (2.79e-1)" "unprognostic (8.97e-2)" "unprognostic (9.47e-2)" 0.2 0.7 2.3 0.1 2.6 1.5 0.2 4.9 3.1 0.3 0.0 0.3 0.2 0.1 0.0 1.3 0.6 0.2 0.1 3.8 0.5 2.7 0.4 0.3 0.1 0.0 0.0 0.2 0.3 0.3 1.4 0.1 0.0 0.4 0.0 0.5 0.5 0.0 0.2 3.1 0.3 0.0 0.0 0.5 0.3 1.6 0.9 0.0 0.4 0.0 0.1 0.1 0.5 1.2 3.4 0.6 0.2 1.4 0.1 0.1 0.6 0.1 0.0 0.2 0.3 2.2 0.3 0.3 0.5 0.0 0.2 1.3 1.7 1.2 0.1 5.1 1.9 0.1 1.3 0.2 0.4 0.5 0.7 0.3 4.0 0.1 0.2 0.5 0.0 1.3 1.0 0.4 0.0 3.2 0.0 0.5 0.4 0.1 1.4 0.2 0.4 0.7 0.5 0.4 0.8 1.1 0.9 0.7 0.4 0.5 4.2 0.1 0.1 0.3 1.7 0.4 0.2 0.4 3.6 0.8 0.3 0.5 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.1 0.0 0.0 2.3 2.6 4.9 3.1 3.8 0.5 0.0 0.0 0.0 0.0 0.9 1.2 0.4 0.0 1.8 0.7 0.3 1.3 0.7 3.3 0.6 0.2 0.7 0.8 0.5 0.0 1.1 0.0 0.0 0.5 0.5 0.6 1.9 1.0 0.4 0.6 0.3 0.3 0.0 0.0 3.2 0.2 1.1 0.3 0.0 0.8 0.0 0.1 0.4 0.0 0.2 0.0 1.4 0.0 2.0 0.6 0.6 0.1 0.3 0.3 0.0 1.9 0.0 0.2 0.0 0.5 0.6 0.4 1.3 0.0 0.4 0.3 0.1 9.7 1.1 0.2 0.0 0.5 0.2 0.8 2.9 0.8 1.4 0.5 0.4 0.1 0.3 0.4 BAIAP2 "BAP2, IRSp53, WAML" ENSG00000175866 "BAR/IMD domain containing adaptor protein 2" Q9UQB8 17 81035122-81117432 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Urothelial cells: 185.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 19.5" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023310, HPA027421" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA 18000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cytosol" "HPA023310: AB_1845264, HPA027421: AB_10602392" "unprognostic (2.20e-1)" "unprognostic (1.84e-3)" "unprognostic (5.81e-2)" "unprognostic (2.28e-2)" "unprognostic (1.73e-1)" "unprognostic (6.97e-3)" "unprognostic (3.73e-3)" "unprognostic (1.53e-1)" "unprognostic (6.77e-2)" "unprognostic (1.45e-2)" "unprognostic (4.23e-2)" "unprognostic (2.94e-1)" "unprognostic (7.04e-2)" "unprognostic (6.77e-2)" "unprognostic (7.15e-2)" "unprognostic (1.62e-2)" "prognostic unfavorable (7.58e-6)" 23.9 18.2 129.1 7.4 140.0 2.6 27.1 95.7 176.1 49.9 104.6 44.0 6.7 30.9 46.5 132.9 37.6 29.3 24.2 163.7 103.1 38.0 85.7 49.1 6.9 68.0 81.0 13.7 13.4 19.9 56.3 31.8 68.3 61.3 12.1 16.2 57.5 27.6 13.1 132.4 14.7 19.3 70.5 11.8 62.3 26.3 119.9 11.8 27.1 9.8 25.3 23.3 73.2 121.9 99.9 45.1 28.1 36.6 22.2 29.0 32.8 40.2 26.1 35.7 15.8 60.9 49.1 0.5 28.3 35.8 73.5 93.6 26.1 46.1 13.7 0.4 32.8 20.2 41.3 46.4 20.7 0.0 28.2 12.5 53.0 29.5 15.4 32.7 19.5 1.1 26.4 0.6 20.6 51.2 4.0 22.3 11.8 65.6 38.1 6.0 6.6 81.3 108.5 34.5 36.8 39.9 64.2 91.3 110.1 23.1 80.4 22.6 23.8 81.6 78.4 13.8 43.4 1.4 0.3 1.4 72.0 3.3 18.3 0.0 7.9 0.5 3.2 9.4 1.0 0.1 1.2 1.0 10.3 0.1 1.3 1.8 5.4 1.9 9.2 19.5 0.5 3.2 129.1 140.0 95.7 176.1 163.7 103.1 68.0 81.0 68.3 70.5 119.9 121.9 74.1 76.9 39.0 13.4 6.2 63.7 138.4 42.3 94.4 37.1 49.4 37.1 22.5 25.8 47.2 22.0 79.2 77.1 16.6 18.8 7.9 9.8 10.5 80.8 10.4 35.7 49.3 0.8 65.3 5.1 9.2 28.0 88.2 79.7 13.4 3.1 45.0 78.6 43.2 11.8 13.6 29.1 24.4 18.3 58.2 29.4 6.8 31.2 40.9 13.1 18.6 18.5 0.0 4.5 5.9 14.8 8.0 3.8 3.1 77.0 3.7 25.4 110.8 19.1 0.0 10.4 13.3 7.6 33.0 103.6 75.3 101.0 13.9 8.2 14.7 185.1 BCAT2 "BCAM, BCT2" ENSG00000105552 "Branched chain amino acid transaminase 2" O15382 19 48795062-48811029 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Amino-acid biosynthesis, Branched-chain amino acid biosynthesis" "Aminotransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RT4: 254.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054091 Enhanced Approved Nucleoplasm,Mitochondria NA NA 25000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Mitochondria" "HPA054091: AB_2682374" "unprognostic (2.58e-2)" "unprognostic (1.23e-2)" "unprognostic (2.16e-1)" "unprognostic (2.51e-3)" "unprognostic (1.54e-1)" "unprognostic (2.97e-2)" "unprognostic (1.69e-1)" "unprognostic (1.17e-2)" "unprognostic (2.98e-2)" "unprognostic (1.03e-1)" "unprognostic (8.32e-3)" "unprognostic (1.06e-1)" "prognostic favorable (3.68e-5)" "unprognostic (1.87e-3)" "unprognostic (1.35e-1)" "unprognostic (2.42e-1)" "unprognostic (7.50e-3)" 27.2 85.4 27.5 11.4 27.8 6.1 25.2 34.6 34.5 29.7 72.3 38.8 14.8 27.0 5.3 33.7 30.2 10.7 63.4 29.0 26.5 40.5 22.1 30.4 14.0 28.2 29.7 53.3 76.7 20.1 30.7 12.4 27.8 38.4 17.4 5.6 29.1 17.0 58.7 28.0 23.7 13.5 26.1 19.7 66.4 20.2 30.8 12.0 28.9 29.4 16.5 56.6 29.0 29.2 62.9 73.3 19.3 40.6 78.1 26.3 34.2 27.3 13.8 32.7 31.7 74.5 37.4 73.3 30.2 24.3 10.1 28.8 29.8 47.4 16.5 46.0 76.0 27.0 32.7 5.0 75.3 36.9 24.2 38.5 29.8 24.2 35.0 31.8 45.5 55.3 34.9 43.8 12.2 74.8 50.4 38.9 16.9 98.5 35.7 75.2 33.1 80.8 30.8 254.3 102.6 29.4 41.0 66.7 20.7 13.3 42.3 17.9 25.9 31.5 30.3 37.6 34.3 40.8 58.4 35.8 17.2 56.7 21.0 0.0 14.4 3.0 14.3 16.1 20.1 23.5 17.5 18.8 25.6 20.3 15.7 14.1 0.6 14.8 6.2 28.9 24.9 12.3 27.5 27.8 34.6 34.5 29.0 26.5 28.2 29.7 27.8 26.1 30.8 29.2 13.1 28.9 44.8 59.7 14.1 6.0 28.3 32.3 14.2 10.4 23.5 17.9 25.5 31.5 20.6 12.9 20.9 67.6 11.0 28.8 72.4 38.6 8.0 16.2 22.4 13.5 19.9 6.3 11.2 21.3 25.2 15.3 32.6 23.8 23.5 18.3 12.8 11.2 26.2 1.7 10.6 30.4 38.7 7.9 10.5 10.2 17.4 7.5 24.9 8.4 21.6 7.3 7.2 9.0 11.2 15.8 17.7 30.1 15.1 16.1 13.9 39.4 13.2 13.4 19.7 9.9 17.3 8.0 19.5 32.6 7.1 45.8 9.5 21.9 33.9 47.7 BCL2L10 "BCL-B, Boo, Diva" ENSG00000137875 "BCL2 like 10" Q9HD36 15 52109263-52112775 "Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 9.6;skin 1: 6.9" "Cell type enhanced" "Detected in many" "Distal tubular cells: 13.7;Proximal enterocytes: 11.4;Proximal tubular cells: 9.8;Squamous epithelial cells: 7.9;Suprabasal keratinocytes: 8.7" "Cancer enhanced" "Detected in many" "liver cancer: 6.4" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "basophil: 1.4" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 8 "NB-4: 34.1" "Not detected" "Not detected" HPA042222 Approved NA NA "Cluster 10: Basophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 44: Endometrium - Transcription" "HPA042222: AB_10794271" "unprognostic (5.33e-4)" "unprognostic (1.26e-1)" "unprognostic (1.58e-1)" "unprognostic (3.22e-4)" "unprognostic (1.19e-2)" "unprognostic (1.20e-1)" "unprognostic (5.07e-2)" "unprognostic (4.80e-3)" "unprognostic (8.86e-2)" "unprognostic (3.47e-2)" "unprognostic (9.52e-2)" "unprognostic (3.83e-1)" "unprognostic (2.18e-9)" "unprognostic (9.59e-2)" "unprognostic (1.86e-1)" "unprognostic (1.92e-1)" "unprognostic (3.20e-2)" 0.2 2.6 1.2 0.3 1.6 0.1 1.0 0.8 1.1 2.3 0.5 1.0 1.9 0.8 0.0 3.5 0.6 0.9 0.0 0.9 1.7 3.1 9.6 0.0 0.2 0.6 0.6 0.4 0.6 0.2 1.2 0.0 0.8 0.5 0.8 0.4 0.8 0.1 0.1 6.9 2.1 0.2 0.5 0.6 0.9 0.2 1.8 0.1 0.3 0.0 0.2 1.2 3.6 0.7 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 1.7 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.7 0.4 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 34.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.2 0.1 4.2 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 1.2 1.6 0.8 1.1 0.9 1.7 0.6 0.6 0.8 0.5 1.8 0.7 0.1 0.0 0.0 0.0 0.6 6.1 5.3 2.5 4.6 1.0 1.7 2.5 0.3 4.3 0.7 0.0 0.0 0.1 0.2 2.8 13.7 2.2 0.0 1.4 1.4 0.3 0.0 0.8 0.4 1.5 0.2 0.3 0.0 5.2 0.0 0.1 0.0 4.5 0.1 0.0 0.2 2.1 6.1 0.0 0.7 0.1 0.3 0.2 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.4 0.7 0.4 1.1 2.0 11.4 9.8 0.4 0.2 0.0 0.2 0.3 0.0 0.1 7.9 8.7 0.1 0.2 0.1 3.1 5.4 BDKRB1 "B1BKR, BKR1, bradyb1" ENSG00000100739 "Bradykinin receptor B1" P46663 14 96256210-96268967 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 23.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 40.8;Basal squamous epithelial cells: 41.5;Fibroblasts: 17.0;Squamous epithelial cells: 22.5;Suprabasal keratinocytes: 17.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 32.0;fHDF/TERT166: 18.8;HHSteC: 29.2;hTEC/SVTERT24-B: 29.2;U-2197: 27.9;U-87 MG: 90.1" "Low region specificity" "Detected in single" HPA002935 Approved NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA002935: AB_1078274" "unprognostic (6.15e-2)" "unprognostic (2.78e-2)" "unprognostic (9.40e-2)" "unprognostic (3.06e-3)" "unprognostic (6.76e-2)" "unprognostic (1.11e-2)" "unprognostic (3.31e-2)" "unprognostic (2.34e-3)" "unprognostic (2.23e-2)" "unprognostic (2.96e-2)" "unprognostic (4.80e-3)" "unprognostic (2.36e-1)" "unprognostic (9.96e-6)" "unprognostic (2.33e-1)" "unprognostic (8.82e-2)" "unprognostic (2.33e-3)" "unprognostic (4.66e-2)" 10.7 0.2 0.4 5.2 0.7 0.0 1.2 1.3 0.9 6.9 0.3 4.2 1.8 0.9 0.6 13.4 5.1 14.1 1.6 0.5 0.3 8.3 0.2 1.3 0.1 0.5 0.4 0.4 6.5 0.0 0.2 0.7 0.5 1.5 2.7 0.2 1.9 0.2 0.1 3.3 3.6 6.0 0.3 0.1 4.5 2.3 0.4 0.1 1.1 0.5 0.4 23.4 7.4 0.6 0.5 1.4 0.0 1.2 2.9 9.9 0.1 2.3 32.0 3.1 0.5 0.0 0.6 0.0 0.1 18.8 1.4 2.4 0.0 0.4 5.0 0.3 0.1 0.0 2.7 0.0 29.2 0.0 0.1 1.0 2.4 29.2 0.6 0.2 0.0 0.0 0.0 0.1 4.2 0.4 0.0 0.0 0.0 1.7 0.2 0.0 7.2 0.2 0.2 0.1 0.7 0.0 8.2 2.4 0.0 0.3 0.0 0.0 0.0 9.5 0.6 27.9 1.8 4.6 9.3 0.0 90.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.7 1.3 0.9 0.5 0.3 0.5 0.4 0.5 0.3 0.4 0.6 1.4 0.0 0.5 0.0 0.0 40.8 2.9 9.0 41.5 1.7 0.0 0.3 0.8 0.0 3.2 0.0 0.0 0.3 0.0 5.5 7.9 2.3 1.1 0.9 3.7 5.0 0.0 0.0 0.4 1.2 1.4 17.0 0.5 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.1 1.1 8.2 0.0 6.1 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 2.3 4.9 0.4 0.0 1.6 2.3 0.1 3.3 0.1 0.0 1.6 2.5 0.9 1.3 22.5 17.2 1.5 0.2 0.0 0.4 2.8 BHLHA15 "BHLHB8, MIST1" ENSG00000180535 "Basic helix-loop-helix family member a15" Q7RTS1 7 98211439-98215457 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "pancreas: 502.8;salivary gland: 145.9" "Cell type enriched" "Detected in single" 25 "Plasma cells: 12.6" "Cancer enriched" "Detected in many" 4 "prostate cancer: 16.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Karpas-707: 53.5;RPMI-8226: 72.0;U-266/70: 67.6" "Not detected" "Not detected" "Not detected" "Not detected" "CAB034083, HPA047834" Enhanced Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 25: Pancreas - Digestion" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Nucleoplasm, Golgi apparatus" "CAB034083: AB_2065216, HPA047834: AB_2680172" "unprognostic (2.80e-2)" "unprognostic (9.45e-3)" "unprognostic (8.10e-2)" "unprognostic (6.66e-2)" "unprognostic (4.33e-3)" "unprognostic (1.10e-2)" "unprognostic (4.05e-2)" "unprognostic (1.37e-1)" "unprognostic (3.60e-1)" "unprognostic (4.28e-2)" "unprognostic (1.46e-1)" "unprognostic (1.88e-1)" "unprognostic (3.70e-4)" "unprognostic (3.36e-1)" "unprognostic (1.94e-1)" "unprognostic (2.95e-1)" "unprognostic (8.25e-3)" 0.1 0.1 0.8 3.6 0.6 0.3 1.5 0.1 2.0 1.9 0.1 4.0 4.0 0.1 0.8 0.9 0.1 0.7 0.2 1.3 0.9 0.6 5.2 0.9 3.8 0.6 0.5 0.4 502.8 0.1 1.5 0.1 0.6 8.5 1.5 0.0 145.9 3.9 0.2 0.6 3.4 0.0 1.0 5.0 31.3 0.2 1.5 0.7 1.9 0.0 4.7 2.5 0.2 0.4 0.3 0.1 0.0 0.0 0.0 0.3 0.4 0.1 0.0 0.3 0.1 0.8 0.9 0.0 1.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 2.8 0.0 0.6 6.7 5.9 0.0 0.1 0.0 0.4 0.4 0.2 0.0 0.2 0.0 0.0 53.5 0.0 0.9 0.0 0.0 0.8 6.2 0.8 0.4 0.0 72.0 0.3 0.0 4.3 1.2 0.0 11.2 0.0 0.0 0.7 0.1 0.0 0.0 0.7 0.1 0.1 67.6 5.4 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.8 0.6 0.1 2.0 1.3 0.9 0.6 0.5 0.6 1.0 1.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 BICD2 KIAA0699 ENSG00000185963 "BICD cargo adaptor 2" Q8TD16 9 92711363-92764833 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "mRNA transport, Protein transport, Translocation, Transport" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 63.4" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 83.6;Squamous epithelial cells: 103.2;Suprabasal keratinocytes: 130.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023013, HPA024452" Enhanced Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Golgi apparatus, Plasma membrane, Cytosol" "HPA023013: AB_1845352, HPA024452: AB_1845353" "unprognostic (9.99e-3)" "unprognostic (1.98e-1)" "unprognostic (7.84e-3)" "unprognostic (2.81e-2)" "unprognostic (4.33e-2)" "unprognostic (2.86e-1)" "unprognostic (2.37e-2)" "unprognostic (1.47e-1)" "unprognostic (1.04e-1)" "unprognostic (6.54e-3)" "unprognostic (8.12e-2)" "unprognostic (1.48e-1)" "prognostic favorable (1.39e-4)" "unprognostic (1.25e-1)" "unprognostic (2.26e-1)" "unprognostic (3.95e-1)" "unprognostic (1.39e-2)" 15.4 10.6 11.4 13.5 10.0 12.0 10.9 10.9 10.5 20.8 7.8 18.5 4.6 15.5 6.0 47.0 12.8 9.4 19.8 11.1 8.6 9.1 8.5 16.0 14.7 11.0 9.8 12.5 8.9 17.7 6.0 10.4 10.3 11.3 5.0 6.5 14.6 13.1 22.3 63.4 10.4 13.7 10.5 17.3 9.5 9.4 10.0 13.8 10.0 15.3 16.8 15.2 30.9 12.3 32.6 26.5 19.2 19.8 36.6 25.1 27.1 30.8 22.2 17.2 13.6 15.6 14.4 36.3 19.5 34.4 22.0 99.4 21.8 49.1 19.4 17.4 23.5 19.2 25.6 21.7 21.8 26.9 30.0 25.8 67.1 28.8 22.0 20.4 26.0 15.4 19.3 27.5 38.1 21.4 25.6 16.7 13.3 23.8 32.0 27.8 41.8 19.3 27.8 27.0 13.4 20.7 21.7 19.9 14.3 19.2 8.2 12.3 34.9 31.8 21.1 53.9 33.9 22.5 17.5 31.9 26.9 16.3 28.4 1.6 3.4 4.4 1.2 3.6 1.2 1.8 1.4 1.6 3.8 2.0 1.3 1.2 7.5 1.1 5.9 3.2 0.9 1.7 11.4 10.0 10.9 10.5 11.1 8.6 11.0 9.8 10.3 10.5 10.0 12.3 21.7 28.9 12.7 14.7 27.6 73.7 17.1 19.2 83.6 12.8 11.4 10.2 54.5 8.6 16.2 7.3 6.2 8.5 26.1 3.4 3.9 10.1 6.5 21.3 26.7 26.4 10.8 16.0 16.2 5.1 6.5 26.0 5.6 21.1 24.1 13.0 19.2 7.5 14.2 15.2 14.0 1.9 12.2 32.4 30.2 7.6 21.1 40.7 16.0 19.7 38.9 22.0 7.2 9.5 18.5 8.5 3.6 33.4 22.1 18.7 0.8 6.7 14.0 6.4 19.7 23.0 33.1 9.7 8.4 103.2 130.8 7.3 17.2 13.8 3.6 20.3 BIRC5 "API4, EPR-1, survivin" ENSG00000089685 "Baculoviral IAP repeat containing 5" O15392 17 78214186-78225636 "Cancer-related genes, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Chromosome partition, Mitosis, Transcription, Transcription regulation" "Protease inhibitor, Repressor, Thiol protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 37.9;lymphoid tissue: 41.0;testis: 19.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 74.7;Early spermatids: 94.1;Erythroid cells: 166.7;Extravillous trophoblasts: 162.0;Spermatocytes: 191.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "T-reg: 14.1" "Lineage enriched" "Detected in many" 6 "T-cells: 14.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA002830, CAB004270" Enhanced Supported "Cytokinetic bridge" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Cytokinetic bridge" "CAB004270: AB_628302, HPA002830: AB_1857672" "unprognostic (8.04e-2)" "unprognostic (3.51e-2)" "unprognostic (4.48e-3)" "unprognostic (2.72e-3)" "unprognostic (3.37e-1)" "unprognostic (3.84e-2)" "prognostic unfavorable (5.28e-6)" "prognostic unfavorable (4.49e-4)" "unprognostic (3.56e-3)" "unprognostic (4.53e-3)" "unprognostic (2.87e-3)" "unprognostic (6.67e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.77e-2)" "unprognostic (4.70e-2)" "unprognostic (1.59e-1)" "unprognostic (1.16e-1)" 0.9 1.1 0.3 8.5 0.5 37.9 5.1 0.6 0.6 1.9 0.4 6.7 7.9 1.6 0.0 12.8 0.6 1.1 0.5 0.4 0.4 0.7 2.1 1.9 16.2 0.6 0.6 0.4 0.6 0.2 0.2 6.1 0.5 0.6 8.0 0.1 1.8 0.2 1.1 5.8 7.6 4.3 0.4 5.8 3.7 19.6 1.0 41.0 0.4 0.1 16.3 2.6 3.2 0.8 139.1 126.2 111.3 121.5 6.7 11.3 41.0 103.6 57.5 144.0 94.2 104.0 52.9 140.7 41.5 60.5 108.7 71.9 113.6 66.6 125.2 48.2 157.5 93.2 71.4 123.1 0.8 90.8 67.0 3.9 4.5 79.8 59.2 21.0 103.5 104.3 118.8 116.0 112.6 79.7 195.5 86.2 83.4 96.3 218.0 100.5 180.2 108.4 34.5 50.2 136.8 94.8 80.3 88.6 71.7 54.1 117.5 84.8 39.5 173.1 152.6 76.0 150.4 83.3 72.2 163.3 63.3 37.8 154.4 0.0 0.0 0.0 0.7 0.0 0.1 2.4 4.1 2.8 0.8 0.2 0.0 0.4 0.5 2.4 0.0 0.2 14.1 3.1 0.3 0.5 0.6 0.6 0.4 0.4 0.6 0.6 0.5 0.4 1.0 0.8 1.2 0.0 20.0 0.0 15.9 8.2 3.7 12.2 2.8 0.7 7.7 8.6 2.3 2.8 10.8 0.0 0.0 74.7 3.3 10.7 0.0 2.0 94.1 5.4 5.1 8.8 3.0 166.7 0.4 0.0 162.0 15.1 8.6 6.9 9.5 42.7 12.8 2.7 52.1 0.0 0.2 17.1 10.2 13.7 13.8 68.4 3.1 9.6 1.8 0.0 0.6 0.4 7.2 0.0 0.3 0.4 2.5 0.7 50.2 2.8 3.2 0.1 2.6 0.5 6.6 0.9 15.2 191.1 58.2 31.3 6.5 19.2 10.1 3.4 38.8 6.3 BLOC1S3 "BLOS3, HPS8" ENSG00000189114 "Biogenesis of lysosomal organelles complex 1 subunit 3" Q6QNY0 19 45178784-45216933 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Albinism, Hermansky-Pudlak syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 39.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050111, HPA070609" Approved Approved "Golgi apparatus" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 34: Spermatids - Unknown function" "Golgi apparatus" "HPA050111: AB_2681019, HPA070609: " "unprognostic (1.17e-1)" "unprognostic (3.97e-2)" "unprognostic (6.94e-3)" "unprognostic (6.26e-2)" "unprognostic (3.14e-1)" "unprognostic (3.04e-2)" "unprognostic (1.75e-2)" "unprognostic (2.30e-2)" "unprognostic (2.01e-1)" "unprognostic (9.49e-2)" "unprognostic (6.39e-2)" "unprognostic (1.68e-1)" "prognostic unfavorable (3.89e-9)" "unprognostic (1.92e-2)" "unprognostic (1.93e-1)" "unprognostic (3.29e-1)" "prognostic favorable (6.86e-4)" 6.7 6.3 7.8 5.9 7.8 12.4 5.7 7.0 8.2 5.7 4.4 5.7 5.3 5.6 5.9 6.4 4.7 3.2 5.2 7.5 6.4 5.7 7.8 5.5 7.6 9.3 8.0 5.6 6.1 4.8 4.4 3.9 8.4 5.7 4.3 3.3 5.6 4.5 4.4 13.2 6.7 4.1 6.8 11.0 7.6 7.2 8.1 4.7 4.7 3.4 7.5 6.6 5.9 9.2 10.4 11.6 3.2 8.1 10.8 7.3 9.7 5.1 8.2 9.5 9.8 7.0 6.6 9.0 12.2 11.9 10.8 16.0 8.5 11.6 6.8 7.9 17.3 12.3 5.5 8.0 15.4 6.0 19.5 10.8 16.3 12.3 17.3 5.4 10.6 5.9 13.2 18.2 5.6 17.8 6.2 9.2 1.8 14.9 14.5 8.9 4.3 7.5 7.0 13.2 6.3 6.0 13.6 22.8 5.1 5.6 9.4 11.1 5.7 9.7 5.5 10.4 8.2 12.7 14.0 6.1 10.6 11.1 7.5 51.1 34.4 30.2 37.4 42.8 31.0 18.4 31.6 28.3 21.4 24.8 25.5 25.5 35.2 24.2 39.9 18.5 29.8 17.8 7.8 7.8 7.0 8.2 7.5 6.4 9.3 8.0 8.4 6.8 8.1 9.2 3.4 0.0 1.7 1.0 5.4 12.7 2.6 1.7 2.2 5.7 4.2 3.2 2.3 1.5 1.5 3.7 0.0 3.7 5.9 4.6 1.9 4.4 17.7 1.9 3.2 5.2 7.2 1.7 2.7 3.7 4.0 3.2 2.0 2.7 8.2 3.0 6.1 6.3 6.1 5.0 2.8 5.0 0.0 8.8 8.9 39.3 6.2 4.7 3.6 1.0 6.8 3.4 11.3 3.5 2.9 5.1 3.2 7.9 4.0 4.9 4.6 4.2 1.7 2.0 0.0 1.9 3.1 1.5 5.1 2.7 13.9 4.5 6.7 3.0 4.1 1.9 BRI3BP "BNAS1, HCCR-2, HCCRBP-3, KG19" ENSG00000184992 "BRI3 binding protein" Q8WY22 12 124993645-125031231 "Predicted membrane proteins, Transporters" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 20.8" "Cell type enhanced" "Detected in many" "Late spermatids: 174.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 13.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Daudi: 114.9;U-698: 161.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014957 Approved Approved Nucleoplasm,Mitochondria NA Yes "Cluster 52: Eosinophils - Transcription" "Cluster 45: Intestine - Brush border" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Mitochondria" "HPA014957: AB_1845447" "unprognostic (1.62e-2)" "unprognostic (6.82e-2)" "unprognostic (1.53e-2)" "unprognostic (9.95e-2)" "unprognostic (4.66e-2)" "unprognostic (1.20e-2)" "prognostic unfavorable (6.87e-4)" "unprognostic (7.65e-3)" "unprognostic (2.84e-2)" "unprognostic (3.47e-3)" "unprognostic (7.40e-2)" "unprognostic (4.82e-2)" "unprognostic (2.72e-3)" "unprognostic (1.44e-3)" "unprognostic (2.20e-1)" "unprognostic (9.20e-2)" "unprognostic (1.55e-1)" 3.3 2.0 9.2 8.9 10.7 5.5 5.5 8.2 10.7 3.0 7.1 15.5 20.8 2.1 2.2 6.8 4.1 4.8 2.5 9.2 7.9 6.9 4.8 2.8 13.8 9.6 9.7 1.5 5.1 9.1 2.1 2.1 10.2 2.9 15.3 10.0 2.5 2.2 1.7 5.5 18.8 2.6 9.1 5.9 8.2 1.8 9.1 7.0 4.4 2.1 16.2 2.5 2.6 9.4 34.1 43.8 13.8 12.5 10.9 5.6 24.1 22.2 4.6 13.7 7.1 36.1 22.3 114.9 27.8 5.0 8.9 38.7 30.7 17.3 10.9 26.9 25.5 58.4 16.9 24.8 2.2 86.8 72.2 2.5 9.9 15.0 7.1 5.3 5.1 41.0 23.5 8.0 12.0 31.3 45.1 33.3 9.9 29.9 17.3 30.2 23.0 30.7 17.3 46.8 19.0 13.2 27.6 26.9 9.2 4.6 48.8 60.8 5.9 13.0 16.2 12.5 23.4 26.9 49.7 161.8 11.9 28.7 29.1 4.2 2.2 13.1 0.8 1.6 0.8 1.4 0.6 0.7 1.7 1.5 0.5 0.7 2.2 0.9 1.2 4.2 0.7 0.6 9.2 10.7 8.2 10.7 9.2 7.9 9.6 9.7 10.2 9.1 9.1 9.4 3.4 9.6 10.4 13.4 23.6 12.2 9.1 8.2 5.2 37.1 14.9 6.3 7.2 31.5 9.2 9.2 14.6 15.4 24.3 65.5 3.9 9.1 25.6 16.1 7.2 5.1 7.8 21.5 32.6 10.4 24.0 7.1 32.1 18.0 18.4 7.2 4.2 27.4 19.8 25.2 43.8 42.8 8.2 31.5 26.1 174.4 1.2 23.6 10.6 11.2 28.8 12.1 9.2 11.1 23.4 17.1 43.3 4.1 39.5 9.6 60.2 12.7 15.0 27.9 0.0 9.2 6.9 1.1 11.5 20.7 18.3 5.2 11.5 6.8 72.6 9.7 BTC ENSG00000174808 Betacellulin P35070 4 74744759-74794523 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Growth factor, Mitogen" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 25.6" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 18.5;Respiratory ciliated cells: 43.1;Skeletal myocytes: 18.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 16.1;MCF7: 5.8;RPTEC TERT1: 9.5;SK-BR-3: 6.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 314000 "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (7.36e-2)" "unprognostic (4.99e-2)" "unprognostic (7.04e-2)" "unprognostic (7.76e-3)" "unprognostic (3.87e-3)" "unprognostic (1.01e-3)" "unprognostic (1.05e-1)" "unprognostic (7.17e-3)" "unprognostic (2.68e-2)" "unprognostic (8.81e-2)" "unprognostic (1.50e-2)" "unprognostic (5.35e-1)" "prognostic favorable (6.10e-5)" "unprognostic (2.33e-1)" "unprognostic (2.45e-2)" "unprognostic (3.16e-2)" "unprognostic (2.31e-3)" 2.5 1.7 0.6 1.8 0.8 0.0 4.1 0.2 0.9 2.7 3.9 25.6 4.3 3.2 6.9 11.0 7.6 6.2 0.4 0.9 0.7 4.4 1.1 4.6 0.1 1.0 1.3 0.9 2.9 7.3 1.6 0.4 0.8 4.6 7.4 4.2 6.9 4.4 0.4 13.7 6.8 10.0 0.9 0.1 6.2 0.6 0.7 0.2 5.8 1.0 0.5 4.6 1.9 0.7 3.3 2.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 1.0 1.1 0.0 16.1 0.0 3.3 0.0 2.3 0.5 0.0 0.1 0.0 0.0 0.3 0.1 0.6 0.0 0.2 0.0 0.0 0.0 1.2 0.3 0.1 2.6 0.1 0.0 0.0 0.1 0.4 5.8 0.1 0.0 0.0 1.7 2.4 0.0 0.0 0.0 9.5 4.6 0.2 0.0 2.4 6.4 0.0 0.0 0.4 0.0 0.0 0.3 0.1 0.3 2.8 0.3 0.0 0.0 2.6 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.8 0.2 0.9 0.9 0.7 1.0 1.3 0.8 0.9 0.7 0.7 2.9 9.6 10.8 0.0 0.0 0.6 3.9 3.7 0.0 2.4 3.9 1.4 0.9 4.3 12.2 11.0 2.1 0.5 0.0 6.1 0.0 4.1 2.0 18.5 1.3 0.7 12.0 0.0 7.7 5.9 0.0 0.7 8.6 10.7 0.0 6.7 2.9 0.4 0.1 0.0 3.2 9.9 10.2 0.0 0.0 0.3 0.3 0.2 0.0 0.0 0.0 10.4 0.0 2.5 0.3 3.3 4.9 0.0 0.0 4.3 1.7 1.1 43.1 5.7 0.0 18.5 5.6 0.0 0.2 8.4 3.0 0.3 0.2 1.2 7.3 7.6 BUB1 "BUB1A, BUB1L, hBUB1" ENSG00000169679 "BUB1 mitotic checkpoint serine/threonine kinase" O43683 2 110637528-110678063 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Chromosome partition, Host-virus interaction, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 11.9;lymphoid tissue: 27.5;testis: 30.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 24.8;Granulosa cells: 66.1;Plasma cells: 35.2;Spermatocytes: 85.6;Spermatogonia: 20.0" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 221.5" "Region enhanced" "Detected in single" "white matter: 1.7" "Not detected" "Not detected" HPA006123 Supported Nucleoplasm,Cytosol NA Yes "Cluster 46: Basophils - DNA binding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 36: HEL - Hemostasis" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "HPA006123: AB_1845498" "unprognostic (7.74e-2)" "unprognostic (3.45e-2)" "unprognostic (9.72e-3)" "prognostic unfavorable (3.65e-4)" "unprognostic (1.61e-1)" "unprognostic (5.62e-3)" "prognostic unfavorable (1.03e-5)" "prognostic unfavorable (3.94e-4)" "unprognostic (1.26e-3)" "unprognostic (1.15e-1)" "prognostic unfavorable (2.37e-5)" "unprognostic (1.76e-1)" "unprognostic (0.00e+0)" "unprognostic (2.45e-2)" "unprognostic (3.64e-1)" "unprognostic (5.01e-2)" "unprognostic (1.28e-1)" 0.5 0.4 0.1 8.4 0.3 11.9 1.2 0.1 0.1 0.9 0.0 4.3 4.0 1.0 3.5 4.7 0.5 0.9 0.6 0.1 0.1 0.3 0.6 1.2 15.9 0.1 0.6 0.4 0.2 0.7 0.0 3.2 0.3 0.3 5.7 0.1 0.9 0.1 0.1 2.7 3.5 2.2 0.0 5.6 1.9 30.3 0.4 27.5 0.4 0.2 17.0 2.4 1.6 0.3 96.0 29.4 68.5 46.8 3.8 5.3 38.8 50.9 32.9 85.6 62.3 58.3 55.0 64.7 30.9 30.1 80.1 43.2 93.9 35.0 105.7 51.4 45.6 221.5 26.2 50.6 0.8 63.5 57.0 1.7 2.8 65.2 33.1 12.7 49.8 73.2 96.8 126.5 76.8 33.7 126.3 39.0 71.2 39.4 55.3 69.3 64.2 102.7 18.3 27.0 48.3 21.4 34.2 31.4 27.2 44.1 24.0 60.6 19.1 39.7 57.5 28.8 69.0 67.3 65.5 75.4 24.2 48.6 69.8 1.1 0.0 0.2 0.2 0.0 0.3 0.5 0.9 0.5 0.1 0.5 0.6 0.4 0.0 0.5 0.0 0.9 1.5 0.3 0.1 0.3 0.1 0.1 0.1 0.1 0.1 0.6 0.3 0.0 0.4 0.3 0.2 0.0 1.5 0.0 5.5 0.5 0.5 2.0 0.6 0.0 0.9 0.8 1.1 0.0 1.6 0.0 0.0 5.8 2.5 2.4 0.0 0.3 13.5 4.5 1.5 1.1 0.0 24.8 0.2 0.0 9.8 2.2 2.0 2.2 0.0 66.1 1.8 0.3 8.1 0.0 0.2 3.1 4.1 1.6 1.4 7.5 0.3 2.0 0.0 0.0 0.6 0.0 0.0 0.5 1.0 0.1 0.0 0.4 35.2 0.5 0.3 0.1 1.8 0.0 6.6 0.2 3.7 85.6 20.0 4.0 0.4 0.7 2.9 0.5 5.9 0.9 BUB1B "Bub1A, BUBR1, MAD3L, SSK1" ENSG00000156970 "BUB1 mitotic checkpoint serine/threonine kinase B" O60566 15 40161023-40221123 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 17.8;lymphoid tissue: 35.7;testis: 22.2" "Cell type enhanced" "Detected in many" "Erythroid cells: 23.5;Spermatocytes: 79.2;Spermatogonia: 26.8" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.1" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" HPA008419 Supported Cytosol Yes Yes "Cluster 24: B-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA008419: AB_1078308" "unprognostic (4.40e-2)" "unprognostic (2.23e-1)" "unprognostic (4.65e-2)" "unprognostic (2.44e-3)" "unprognostic (9.66e-2)" "unprognostic (3.52e-2)" "prognostic unfavorable (7.43e-6)" "prognostic unfavorable (3.56e-4)" "unprognostic (3.69e-3)" "unprognostic (2.32e-1)" "prognostic unfavorable (1.79e-4)" "unprognostic (1.76e-2)" "unprognostic (0.00e+0)" "unprognostic (3.75e-2)" "unprognostic (4.66e-2)" "unprognostic (2.20e-1)" "unprognostic (3.94e-2)" 0.4 0.5 0.1 6.7 0.1 17.8 1.6 0.3 0.2 1.0 7.7 4.6 4.7 1.2 0.3 5.2 0.6 0.6 0.3 0.3 0.1 0.3 0.4 1.0 12.6 0.0 0.1 0.2 0.2 0.2 0.1 3.4 0.1 0.4 6.0 0.1 0.9 0.2 0.0 3.5 4.1 2.1 0.0 3.1 2.4 22.2 0.2 35.7 0.5 0.0 15.0 1.5 1.7 0.0 66.5 32.8 103.0 41.5 2.5 7.1 33.2 60.9 34.2 64.6 55.7 48.1 25.0 59.7 33.5 22.7 59.0 72.6 98.8 33.2 70.5 51.8 52.1 86.4 83.6 45.5 0.2 79.0 45.7 1.6 2.0 39.2 37.1 12.9 47.7 66.5 76.4 61.7 65.6 22.5 62.5 48.9 70.2 55.6 36.8 66.5 83.7 45.2 19.9 33.1 67.1 40.8 38.0 35.9 13.3 45.1 41.9 40.9 27.6 49.3 51.8 49.2 55.5 32.1 58.2 95.6 26.3 87.8 65.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.1 0.2 1.1 0.0 0.1 0.0 0.1 0.0 0.8 0.0 0.1 0.1 0.1 0.3 0.2 0.3 0.1 0.0 0.1 0.1 0.0 0.2 0.0 0.1 3.2 1.1 0.3 1.8 0.8 0.3 1.0 1.8 0.7 0.9 2.0 0.8 0.0 1.9 0.0 0.0 5.4 0.6 1.8 0.0 0.4 3.0 0.9 1.4 1.0 0.0 23.5 0.7 0.0 6.7 2.4 5.6 2.1 0.0 12.9 1.1 0.3 5.2 0.0 0.7 2.5 0.0 1.9 1.7 3.3 1.5 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 1.5 0.4 12.6 0.3 0.3 0.1 0.2 0.2 6.6 0.2 1.7 79.2 26.8 6.9 0.3 0.8 1.8 0.8 5.4 0.6 C11orf49 "FLJ22210, MGC4707" ENSG00000149179 "Chromosome 11 open reading frame 49" Q9H6J7 11 46936689-47164385 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 140.0;Excitatory neurons: 140.8;Inhibitory neurons: 112.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040051, HPA040280" Uncertain Approved "Nuclear speckles" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear speckles" "HPA040051: AB_10795412, HPA040280: AB_10795363" "unprognostic (3.11e-2)" "unprognostic (3.01e-1)" "unprognostic (2.15e-1)" "unprognostic (1.06e-2)" "unprognostic (6.65e-2)" "unprognostic (7.76e-2)" "prognostic unfavorable (2.18e-5)" "unprognostic (1.27e-1)" "unprognostic (2.76e-1)" "unprognostic (1.72e-1)" "unprognostic (2.14e-2)" "unprognostic (1.55e-1)" "unprognostic (1.54e-2)" "unprognostic (1.36e-1)" "unprognostic (1.11e-1)" "unprognostic (1.07e-1)" "unprognostic (5.34e-3)" 8.1 13.4 52.4 6.2 51.6 3.3 10.0 45.9 54.7 15.6 46.1 14.3 11.2 16.8 14.1 9.7 32.5 9.6 12.3 52.4 53.3 15.7 3.9 12.1 6.3 47.0 53.9 14.9 12.7 22.6 30.3 6.8 49.2 12.4 11.4 21.8 11.0 13.2 7.3 31.6 11.9 12.8 46.2 7.0 15.4 20.2 53.7 13.7 16.1 6.4 7.2 11.9 11.4 45.5 10.9 30.6 37.9 27.9 17.8 25.7 9.5 11.7 26.9 24.6 29.9 6.9 17.0 9.1 12.3 24.4 29.7 14.8 18.8 28.7 20.9 18.1 27.2 12.2 36.6 12.6 30.5 14.6 16.2 17.5 19.1 11.2 16.4 47.0 27.6 22.1 10.3 11.7 18.2 22.8 23.0 16.2 14.3 26.5 16.4 8.2 9.5 10.1 43.3 11.7 25.5 36.5 13.4 14.9 14.7 19.7 25.0 8.5 6.5 13.8 11.0 22.0 17.7 10.4 9.2 7.5 33.7 3.0 17.5 12.7 10.2 9.0 19.2 13.7 23.0 24.1 18.1 22.7 24.6 17.6 19.1 20.3 0.3 25.2 10.3 21.8 19.0 18.3 52.4 51.6 45.9 54.7 52.4 53.3 47.0 53.9 49.2 46.2 53.7 45.5 6.6 9.6 26.7 140.0 9.9 13.0 16.4 30.6 12.0 22.9 12.0 13.0 9.4 12.8 24.0 23.9 18.8 19.4 5.6 18.3 46.9 30.2 53.2 42.8 20.4 10.2 19.2 8.0 140.8 20.4 13.4 18.0 25.5 14.1 16.4 23.3 8.6 2.4 9.9 37.0 112.7 12.8 22.4 3.3 7.0 35.8 12.8 6.2 12.4 41.2 10.9 45.0 7.2 93.0 71.9 16.2 21.2 20.3 5.8 8.1 22.1 33.4 66.7 53.1 6.6 12.2 13.5 63.3 7.6 10.5 18.0 10.0 10.8 32.6 13.7 12.1 C1orf158 MGC35194 ENSG00000157330 "Chromosome 1 open reading frame 158" Q8N1D5 1 12746200-12763699 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "choroid plexus: 18.1;fallopian tube: 26.7;testis: 48.9" "Cell type enhanced" "Detected in some" "Early spermatids: 223.3;Endometrial ciliated cells: 50.3;Late spermatids: 92.8;Respiratory ciliated cells: 88.1;Spermatocytes: 70.7" "Group enriched" "Detected in some" 6 "endometrial cancer: 1.6;glioma: 1.0;ovarian cancer: 0.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA028396 Uncertain Cytosol NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "HPA028396: AB_10603451" "unprognostic (1.11e-2)" "unprognostic (4.94e-3)" "unprognostic (4.62e-1)" "unprognostic (8.00e-2)" "unprognostic (4.18e-1)" "unprognostic (1.03e-2)" "unprognostic (2.45e-1)" "unprognostic (3.51e-1)" "unprognostic (1.35e-1)" "unprognostic (2.68e-2)" 0.0 0.0 0.9 0.0 1.1 0.3 0.0 1.0 0.4 1.1 18.1 0.0 0.0 0.4 0.1 0.1 26.7 0.0 0.0 0.9 1.0 0.0 0.0 1.9 0.1 4.3 5.9 0.1 0.1 0.0 0.6 0.1 3.4 0.0 0.0 0.1 0.1 0.0 1.2 0.4 0.0 0.0 3.3 0.1 0.1 48.9 1.9 0.0 0.6 0.0 0.0 0.0 0.0 3.6 0.0 0.2 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.1 0.1 0.0 0.0 0.0 0.9 1.1 1.0 0.4 0.9 1.0 4.3 5.9 3.4 3.3 1.9 3.6 0.0 3.2 0.5 0.3 0.0 0.0 0.1 3.0 0.0 0.0 0.0 0.0 0.3 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 223.3 50.3 0.4 0.2 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.7 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.1 0.0 0.0 92.8 1.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.1 0.0 0.1 88.1 0.0 6.6 0.1 1.3 70.7 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 C1orf68 "LEP7, XP32" ENSG00000198854 "Chromosome 1 open reading frame 68" Q5T750 1 152719522-152720470 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "skin 1: 678.3" "Cell type enriched" "Detected in some" 14 "Suprabasal keratinocytes: 78.3" "Group enriched" "Detected in some" 13 "head and neck cancer: 2.4;melanoma: 6.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "HaCaT: 1.8" "Not detected" "Not detected" HPA057942 Approved "Plasma membrane,Cytosol" NA NA 220000 "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "Plasma membrane" Cytosol "HPA057942: " "unprognostic (1.73e-1)" "unprognostic (7.46e-2)" "unprognostic (9.34e-2)" 0.4 0.0 0.0 0.0 0.0 0.2 42.9 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 678.3 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.8 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 78.3 0.0 0.1 0.0 0.0 0.0 C1QB ENSG00000173369 "Complement C1q B chain" 1 22652762-22661637 "Human disease related genes, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "lung: 546.4;lymphoid tissue: 990.2" "Group enriched" "Detected in many" 28 "Hofbauer cells: 1451.0;Kupffer cells: 4559.7;Macrophages: 1747.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 71 "intermediate monocyte: 140.6;non-classical monocyte: 101.2" "Lineage enriched" "Detected in many" 85 "monocytes: 140.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052116 Approved "Secreted to blood" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 4: Macrophages - Innate immune response" "HPA052116: AB_2681735" "unprognostic (1.42e-1)" "unprognostic (3.36e-2)" "unprognostic (5.61e-3)" "unprognostic (8.20e-2)" "unprognostic (5.93e-2)" "unprognostic (4.09e-1)" "unprognostic (1.25e-1)" "unprognostic (2.35e-1)" "unprognostic (2.87e-2)" "unprognostic (2.21e-1)" "unprognostic (2.63e-2)" "unprognostic (1.57e-1)" "prognostic unfavorable (9.58e-6)" "unprognostic (4.14e-2)" "unprognostic (7.76e-3)" "unprognostic (4.83e-2)" "unprognostic (2.35e-2)" 439.2 229.0 95.8 149.4 94.2 53.5 87.1 97.2 148.7 65.4 132.6 162.0 186.0 27.7 26.4 63.0 50.5 194.9 62.6 89.8 107.7 18.3 243.4 546.4 514.6 161.0 143.3 39.6 40.0 28.5 1.8 249.2 138.4 28.0 146.0 7.8 44.9 51.2 5.3 6.1 186.1 261.4 138.2 990.2 88.0 39.9 142.2 72.0 23.6 38.6 58.4 255.8 1.1 185.8 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.8 0.4 0.0 0.0 0.5 0.3 0.6 0.0 0.0 0.5 0.8 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.8 0.0 0.1 0.1 0.0 0.2 0.0 1.7 0.0 0.0 140.6 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.4 0.8 101.2 0.0 0.0 5.3 95.8 94.2 97.2 148.7 89.8 107.7 161.0 143.3 138.4 138.2 142.2 185.8 13.8 12.8 22.1 0.0 17.1 6.2 2.1 0.0 1.8 1.2 4.9 23.1 5.5 24.3 10.5 3.7 0.0 6.6 2.7 0.6 0.0 0.0 3.3 0.1 0.2 65.9 0.0 32.8 0.1 0.0 9.6 5.9 0.0 0.1 11.4 0.1 52.1 26.0 1451.0 0.0 0.1 0.0 0.0 4559.7 92.1 7.8 8.4 1747.2 0.0 34.7 5.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 2.3 1.0 0.3 1.1 3.6 3.9 59.2 4.0 3.2 0.4 0.9 5.7 4.5 9.6 6.1 0.2 0.0 1.5 C2orf72 LOC257407 ENSG00000204128 "Chromosome 2 open reading frame 72" A6NCS6 2 231037523-231049719 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 14.6;liver: 18.7" "Cell type enhanced" "Detected in many" "Astrocytes: 163.2;Cholangiocytes: 47.1;Hepatocytes: 129.1;Oligodendrocyte precursor cells: 45.8;Paneth cells: 51.3" "Cancer enhanced" "Detected in many" "liver cancer: 40.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 8.9;CACO-2: 2.2;EFO-21: 3.3;OE19: 4.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044962 Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 15: Liver - Metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoplasm, Plasma membrane" "HPA044962: AB_10960863" "unprognostic (4.90e-2)" "unprognostic (7.03e-2)" "unprognostic (2.15e-1)" "unprognostic (7.44e-3)" "unprognostic (2.88e-2)" "unprognostic (6.41e-2)" "unprognostic (3.38e-1)" "unprognostic (6.51e-2)" "unprognostic (6.25e-3)" "unprognostic (1.84e-1)" "prognostic favorable (5.27e-4)" "unprognostic (2.65e-1)" "prognostic unfavorable (4.74e-4)" "unprognostic (2.78e-1)" "unprognostic (7.23e-3)" "unprognostic (2.70e-2)" "unprognostic (5.19e-2)" 0.0 0.0 6.7 0.0 8.2 0.0 0.3 4.3 8.8 0.0 0.0 3.0 0.6 0.0 0.1 0.0 0.0 0.4 0.0 8.7 6.2 0.2 18.7 0.1 0.0 8.4 12.1 0.0 1.4 0.2 1.1 0.9 6.0 0.5 0.7 0.0 0.1 0.0 0.0 0.1 1.1 0.0 5.8 0.0 1.5 0.1 14.6 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.5 0.4 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 2.2 0.0 0.0 3.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 4.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 1.5 0.1 1.0 0.5 0.5 0.6 0.0 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 8.2 4.3 8.8 8.7 6.2 8.4 12.1 6.0 5.8 14.6 6.1 0.0 0.0 0.0 163.2 0.5 0.1 0.1 0.0 0.0 1.9 5.9 6.0 0.5 47.1 0.0 0.0 0.0 1.8 0.2 32.8 1.9 3.9 13.6 0.1 0.2 0.2 4.9 10.7 33.4 2.0 11.9 0.2 4.6 0.1 0.0 0.1 3.6 129.1 0.6 0.0 15.0 14.8 0.0 2.9 0.0 30.8 0.3 0.2 1.8 6.5 0.0 15.7 0.0 45.8 20.1 0.8 51.3 4.1 0.2 0.7 10.7 1.8 0.0 0.3 0.0 0.0 0.1 0.5 0.9 0.0 0.0 5.2 0.3 0.0 28.8 0.3 CA12 HsT18816 ENSG00000074410 "Carbonic anhydrase 12" O43570 15 63321378-63381846 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins" Lyase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 290.2;skin 1: 142.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 174.6;Distal enterocytes: 422.6;Paneth cells: 160.8;Squamous epithelial cells: 185.3;Suprabasal keratinocytes: 252.2;Undifferentiated cells: 138.8" "Cancer enhanced" "Detected in all" "renal cancer: 109.3" "Region enhanced" "Detected in many" "basal ganglia: 42.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 213.0;ASC TERT1: 213.0;RT4: 226.2;SK-BR-3: 177.9;T-47d: 286.8;U-138 MG: 300.5;U-87 MG: 361.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008773, CAB025181, CAB062549, CAB068179, HPA073203" Enhanced NA NA 52000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB025181: , CAB062549: AB_2665617, CAB068179: AB_2665616, HPA008773: AB_1078394, HPA073203: AB_2686580" "unprognostic (2.01e-1)" "unprognostic (8.38e-3)" "unprognostic (3.47e-1)" "unprognostic (3.25e-3)" "unprognostic (2.73e-2)" "unprognostic (2.47e-2)" "unprognostic (7.48e-2)" "unprognostic (3.43e-3)" "unprognostic (2.29e-1)" "unprognostic (4.67e-2)" "prognostic unfavorable (3.80e-6)" "unprognostic (2.59e-1)" "unprognostic (1.51e-1)" "unprognostic (2.38e-1)" "unprognostic (6.56e-2)" "unprognostic (7.26e-2)" "unprognostic (1.21e-1)" 8.3 0.2 6.1 18.7 42.9 0.1 42.8 5.2 7.2 50.7 129.0 104.1 0.4 28.4 4.1 75.4 25.0 7.7 3.2 6.8 6.6 290.2 0.7 3.0 0.3 0.9 9.6 0.6 70.2 0.3 10.7 2.3 3.2 5.5 94.2 1.9 26.3 8.7 0.6 142.1 8.2 56.2 0.9 0.8 7.9 0.6 16.1 0.1 4.6 0.1 8.7 27.4 49.0 1.5 0.0 213.0 3.5 0.5 27.3 213.0 11.2 15.7 13.7 2.5 4.1 1.6 0.5 0.0 51.4 12.6 81.7 1.1 0.0 10.4 6.2 0.3 7.7 0.0 13.9 0.4 0.6 0.0 0.3 81.3 11.4 63.6 20.4 0.1 2.7 0.1 0.0 0.3 2.8 125.2 0.3 0.2 3.4 0.0 33.4 0.1 0.0 0.1 0.2 226.2 1.8 0.2 0.9 177.9 0.0 2.1 286.8 0.1 0.4 300.5 16.0 10.1 0.2 0.0 0.0 0.1 361.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 42.9 5.2 7.2 6.8 6.6 0.9 9.6 3.2 0.9 16.1 1.5 0.7 0.0 6.9 11.4 1.1 174.6 20.0 87.7 93.4 0.1 93.5 50.4 1.3 1.5 30.3 40.5 0.0 0.4 1.6 422.6 54.8 17.2 12.1 28.4 6.2 2.1 8.4 0.0 1.3 58.4 2.0 14.6 8.2 75.0 1.3 0.3 0.0 0.2 0.6 0.0 0.8 111.4 20.3 0.3 11.9 3.9 0.0 4.0 23.2 0.0 0.0 2.7 0.0 1.0 0.1 10.2 160.8 0.0 0.0 19.8 15.6 73.9 6.9 0.2 0.0 0.2 4.1 0.0 0.0 185.3 252.2 1.8 2.8 0.1 138.8 17.4 CA14 ENSG00000118298 "Carbonic anhydrase 14" Q9ULX7 1 150257251-150265078 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 33.3;retina: 39.4;skeletal muscle: 33.7;tongue: 47.4" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 69.5;Melanocytes: 53.4;Muller glia cells: 164.5;Oligodendrocytes: 25.7" "Cancer enriched" "Detected in many" 5 "melanoma: 23.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "AF22: 102.2;AN3-CA: 65.9;NTERA-2: 83.9;SK-MEL-30: 217.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008482 Approved Approved "Plasma membrane" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 5: Muller glia cells - Visual perception" "Plasma membrane" "HPA008482: AB_1078395" "unprognostic (3.06e-2)" "unprognostic (1.67e-1)" "unprognostic (2.10e-2)" "unprognostic (3.25e-2)" "prognostic favorable (8.47e-4)" "unprognostic (7.28e-2)" "unprognostic (4.48e-2)" "unprognostic (1.49e-1)" "unprognostic (2.10e-1)" "unprognostic (2.47e-1)" "unprognostic (5.46e-2)" "unprognostic (1.73e-1)" "unprognostic (5.89e-3)" "unprognostic (1.91e-1)" "unprognostic (1.49e-1)" "unprognostic (1.22e-1)" "unprognostic (5.80e-2)" 0.0 0.2 8.6 0.2 14.4 1.2 0.3 15.9 27.6 0.1 33.3 3.8 0.4 0.1 0.4 1.9 1.7 0.6 7.6 8.7 11.3 0.3 8.7 0.2 0.1 14.3 14.0 1.4 0.2 3.4 0.5 0.3 14.6 4.0 0.7 39.4 0.4 20.3 33.7 5.4 1.3 0.5 12.5 0.2 1.2 0.5 13.3 0.0 1.0 47.4 0.0 0.6 0.1 20.6 0.9 0.2 102.2 65.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.7 0.1 0.5 0.0 0.1 0.3 0.2 0.1 0.0 0.2 1.1 0.3 0.3 6.9 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.8 0.1 0.6 0.0 0.9 0.3 0.3 83.9 0.4 1.1 0.1 0.3 0.3 0.0 0.2 3.2 1.8 0.0 0.3 217.9 14.6 0.8 0.4 0.1 0.1 0.2 0.2 0.4 0.9 4.9 0.4 0.7 0.5 0.2 0.0 0.2 0.4 0.4 0.5 0.1 0.5 0.2 0.3 0.0 0.6 0.3 0.3 0.5 0.0 0.1 0.6 0.0 0.0 8.6 14.4 15.9 27.6 8.7 11.3 14.3 14.0 14.6 12.5 13.3 20.6 0.1 3.2 0.5 0.3 0.2 2.2 0.3 0.3 0.0 1.3 0.1 0.0 69.5 0.0 0.7 0.0 0.0 0.4 0.0 0.3 0.0 0.8 0.0 0.3 0.1 0.6 0.0 0.0 0.1 0.7 0.1 3.4 0.0 0.2 0.0 0.0 0.0 6.1 0.1 0.0 0.1 0.3 0.0 0.3 0.9 0.2 0.9 0.1 53.4 0.0 0.0 164.5 0.0 0.0 25.7 1.9 0.3 3.4 0.0 0.3 0.0 0.1 0.1 4.9 0.0 0.6 0.5 0.0 0.2 0.0 0.4 0.3 0.1 0.0 0.2 0.5 CARMIL3 "BC008134, C14orf121, crml-1, LRRC16B" ENSG00000186648 "Capping protein regulator and myosin 1 linker 3" Q8ND23 14 24052009-24069729 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 3.6;pituitary gland: 8.1;skin 1: 3.9;testis: 2.2" "Cell type enhanced" "Detected in single" "Collecting duct cells: 1.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 5.5;HMC-1: 3.7;Karpas-707: 3.3;SCLC-21H: 5.4;SH-SY5Y: 2.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030596 Uncertain NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "HPA030596: AB_10603012" "unprognostic (2.67e-2)" "unprognostic (2.07e-3)" "unprognostic (1.50e-1)" "unprognostic (3.09e-2)" "unprognostic (6.17e-2)" "unprognostic (1.29e-4)" "unprognostic (6.13e-2)" "unprognostic (8.92e-4)" "unprognostic (4.02e-1)" "unprognostic (7.08e-2)" "unprognostic (1.39e-4)" "unprognostic (4.49e-2)" "unprognostic (1.17e-1)" "unprognostic (7.01e-2)" "unprognostic (1.25e-2)" "unprognostic (4.19e-1)" "unprognostic (2.16e-1)" 0.1 0.3 2.0 0.3 1.5 0.2 0.3 3.6 2.1 0.3 0.0 0.5 0.5 0.2 0.0 0.6 0.1 0.3 0.1 1.9 1.3 0.7 0.2 0.3 0.3 2.0 1.4 0.1 0.7 0.0 8.1 0.0 2.0 0.3 0.1 1.0 0.6 0.0 0.0 3.9 0.7 0.0 0.5 0.5 0.3 2.2 1.9 0.1 0.5 0.0 0.4 0.1 0.5 1.8 0.0 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.9 0.0 0.1 0.1 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.3 0.0 0.2 0.8 0.0 0.3 0.1 0.1 0.4 0.0 0.0 0.0 0.0 5.4 2.6 0.0 0.2 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 1.5 3.6 2.1 1.9 1.3 2.0 1.4 2.0 0.5 1.9 1.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 CBLC "CBL-3, CBL-SL, RNF57" ENSG00000142273 "Cbl proto-oncogene C" Q9ULV8 19 44777869-44800652 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 39.3;intestine: 50.9;skin 1: 42.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 108.6;Pancreatic endocrine cells: 95.0;Paneth cells: 108.1;Proximal enterocytes: 154.6;Undifferentiated cells: 67.1;Urothelial cells: 76.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 43.6;BEWO: 28.9;CACO-2: 28.3;CAPAN-2: 56.9;HaCaT: 41.0;HBEC3-KT: 34.8;hTCEpi: 26.0;OE19: 37.3;RT4: 34.7;SK-BR-3: 31.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB008087, HPA035266" Approved Approved Nucleoplasm,Aggresome NA NA "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Aggresome "CAB008087: AB_2228531, HPA035266: AB_2674542" "unprognostic (1.58e-1)" "unprognostic (2.25e-1)" "unprognostic (8.21e-3)" "unprognostic (1.55e-1)" "unprognostic (3.04e-2)" "unprognostic (3.91e-2)" "unprognostic (1.67e-1)" "unprognostic (2.13e-2)" "unprognostic (3.82e-1)" "unprognostic (7.39e-2)" "unprognostic (1.06e-2)" "unprognostic (1.85e-1)" "prognostic favorable (3.11e-6)" "unprognostic (3.50e-1)" "unprognostic (8.25e-3)" "unprognostic (2.90e-2)" "unprognostic (2.21e-3)" 0.1 0.1 0.0 3.1 0.0 0.0 5.1 0.0 0.1 8.0 0.0 25.0 50.9 0.9 0.1 39.3 2.5 4.4 0.0 0.0 0.0 7.4 21.1 1.3 0.0 0.0 0.0 0.1 20.6 1.6 0.5 0.4 0.0 11.8 11.7 0.1 13.3 2.4 0.1 42.4 38.6 0.6 0.0 0.0 17.7 0.7 0.0 0.3 1.7 0.0 4.0 8.3 18.4 0.0 43.6 0.0 0.0 0.1 0.0 0.0 28.9 0.0 0.0 0.0 0.0 28.3 56.9 0.0 0.0 0.0 0.0 41.0 0.0 34.8 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 26.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 37.3 0.0 0.0 0.0 0.0 0.0 34.7 0.4 0.1 0.0 31.1 0.0 0.2 22.5 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.6 0.0 0.1 15.0 44.0 30.8 16.5 0.0 9.3 7.4 0.2 4.3 27.7 7.3 0.0 5.8 0.2 108.6 1.9 53.8 0.1 7.0 1.3 0.9 17.4 0.0 0.4 48.9 2.3 0.5 59.7 15.5 0.0 0.0 0.0 11.1 0.3 0.0 0.9 40.0 18.3 0.0 1.4 0.3 0.0 0.4 0.0 0.0 0.6 0.0 0.0 1.0 0.3 95.0 108.1 0.0 0.1 34.4 154.6 17.2 9.8 0.0 0.0 0.0 1.3 0.0 2.6 29.9 25.7 2.5 0.7 0.0 67.1 76.9 CCDC137 MGC16597 ENSG00000185298 "Coiled-coil domain containing 137" Q6PK04 17 81666737-81673904 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052637, HPA053914" Uncertain Enhanced "Nucleoli,Mitotic chromosome" Yes No "Cluster 27: Non-specific - Gene expression" "Cluster 27: Brain & Skin - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Mitotic chromosome" "HPA052637: AB_2681894, HPA053914: AB_2682306" "unprognostic (3.04e-1)" "unprognostic (5.82e-2)" "unprognostic (1.76e-1)" "unprognostic (3.07e-2)" "unprognostic (1.68e-2)" "unprognostic (2.24e-1)" "prognostic unfavorable (1.35e-7)" "prognostic unfavorable (8.32e-4)" "unprognostic (2.21e-2)" "unprognostic (8.33e-3)" "unprognostic (1.26e-1)" "unprognostic (1.16e-1)" "prognostic unfavorable (1.16e-7)" "unprognostic (4.26e-2)" "unprognostic (2.01e-1)" "unprognostic (3.93e-1)" "unprognostic (1.39e-1)" 8.2 9.5 13.8 12.3 13.7 17.7 7.6 13.5 17.5 10.7 14.2 9.3 11.4 7.5 5.5 23.1 7.8 6.1 6.5 13.7 13.8 10.2 10.8 7.7 16.3 14.4 14.3 6.7 8.2 7.0 6.2 7.7 14.7 11.7 5.8 2.8 9.9 6.4 7.7 22.8 10.7 6.0 13.4 15.6 8.8 10.4 14.5 11.8 7.8 4.5 11.5 9.8 13.8 14.3 38.0 62.8 21.5 35.3 13.9 13.1 35.2 41.6 19.7 53.0 30.6 55.1 22.8 33.8 22.4 21.2 36.6 47.9 34.5 43.8 30.6 19.4 51.7 51.6 30.1 48.0 20.7 46.6 37.5 19.8 26.3 47.6 26.3 14.6 37.4 41.1 53.3 19.1 28.3 34.5 45.7 56.6 46.9 32.9 59.8 55.4 34.6 24.1 19.8 29.6 45.1 57.7 41.1 87.8 37.1 28.9 58.8 48.3 27.8 82.0 53.5 34.9 65.9 53.1 28.7 36.8 30.8 42.9 48.8 2.2 7.7 11.7 11.5 9.6 6.3 10.4 8.7 8.8 7.5 13.2 9.2 8.8 3.3 13.1 11.9 12.9 9.8 5.9 13.8 13.7 13.5 17.5 13.7 13.8 14.4 14.3 14.7 13.4 14.5 14.3 17.9 22.4 17.0 5.9 29.8 31.7 22.8 19.7 74.6 6.8 17.4 13.7 6.7 15.7 20.9 12.9 2.1 25.7 31.5 19.7 19.6 25.2 1.7 26.5 32.9 20.3 7.2 37.5 4.5 21.4 41.0 16.5 29.0 29.4 19.6 28.1 15.4 11.8 24.3 18.5 4.6 17.0 14.2 12.9 11.5 1.7 13.7 16.8 16.0 4.7 24.2 13.8 37.0 4.0 5.0 35.2 16.0 13.5 25.7 40.0 12.4 15.9 21.6 9.1 6.6 13.7 22.3 30.8 44.9 57.0 34.4 20.8 29.7 22.8 22.4 24.2 CCDC160 ENSG00000203952 "Coiled-coil domain containing 160" A6NGH7 X 134237047-134246207 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 16.5" "Cell type enhanced" "Detected in many" "Distal tubular cells: 45.0;Early spermatids: 14.8;Endometrial ciliated cells: 28.1;Respiratory ciliated cells: 36.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "AF22: 29.7;RPTEC TERT1: 8.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (7.45e-3)" "unprognostic (2.79e-2)" "prognostic favorable (2.31e-4)" "unprognostic (1.98e-1)" "unprognostic (5.11e-4)" "unprognostic (4.22e-2)" "unprognostic (2.07e-2)" "prognostic favorable (7.62e-6)" "unprognostic (3.32e-2)" "unprognostic (4.51e-2)" "prognostic favorable (2.21e-4)" "unprognostic (5.23e-2)" "unprognostic (1.41e-1)" "unprognostic (2.75e-1)" "unprognostic (2.44e-3)" 0.2 0.0 2.2 0.1 2.2 0.2 3.9 2.8 2.7 2.9 3.9 0.2 0.0 0.7 1.7 0.4 3.3 1.1 0.1 2.2 2.4 6.0 0.0 0.4 0.5 2.5 2.5 1.3 0.5 5.1 0.6 0.2 2.7 1.8 0.1 1.0 16.5 2.6 1.0 0.3 0.0 0.0 2.1 0.4 1.0 2.0 2.3 0.0 0.2 0.0 0.1 0.5 0.3 2.6 0.0 0.0 29.7 2.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.5 0.0 0.5 0.0 0.3 0.0 0.0 0.1 0.3 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 4.1 0.0 0.0 0.0 0.1 0.0 8.3 2.4 0.0 0.1 0.0 0.3 0.4 2.9 3.7 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 2.2 2.8 2.7 2.2 2.4 2.5 2.5 2.7 2.1 2.3 2.6 0.2 0.0 0.0 5.5 0.0 0.0 1.0 9.3 0.6 0.3 9.6 9.0 0.5 1.5 10.2 9.2 0.0 0.0 0.0 0.0 45.0 3.2 14.8 28.1 0.5 0.3 0.0 0.0 0.4 0.0 0.3 0.8 0.0 2.5 0.0 0.8 0.4 0.0 0.5 0.0 0.6 0.0 0.0 0.0 0.0 2.9 0.6 0.1 1.8 1.0 0.0 6.9 0.0 6.0 5.6 0.2 0.0 0.4 0.0 1.8 0.0 7.7 36.0 0.6 0.0 0.7 0.6 6.7 10.1 2.3 0.0 0.0 0.1 0.1 0.0 1.4 CCDC172 "C10orf96, MGC35062" ENSG00000182645 "Coiled-coil domain containing 172" P0C7W6 10 116324448-116380029 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "retina: 3.1;testis: 12.2" "Cell type enhanced" "Detected in some" "Early spermatids: 32.9;Late spermatids: 9.6;Spermatocytes: 107.9;Spermatogonia: 22.9" "Cancer enriched" "Detected in single" 14 "testis cancer: 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 21 "NTERA-2: 31.4" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 77: Retina - Visual perception" "Cluster 5: NTERA-2 - Transcription" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "unprognostic (9.85e-2)" 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.2 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 12.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 31.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.3 0.1 0.3 0.2 0.1 0.1 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.9 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 9.6 0.9 0.1 0.0 0.0 0.0 1.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 107.9 22.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CCL27 "ALP, CTACK, CTAK, ESkine, ILC, PESKY, SCYA27, skinkine" ENSG00000213927 "C-C motif chemokine ligand 27" Q9Y4X3 9 34661880-34664048 "Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "skin 1: 485.0" "Group enriched" "Detected in some" 26 "Basal keratinocytes: 704.5;Suprabasal keratinocytes: 1004.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 1.9" "Not detected" "Not detected" HPA073848 Enhanced "Secreted to blood" NA NA 436000 1800000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 61: Skin - Cornification" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 28: Keratinocytes - Keratinization" "HPA073848: AB_2732243" 0.3 0.0 1.8 0.1 1.8 1.6 27.6 3.5 4.8 0.6 1.5 0.1 0.3 0.7 3.1 0.7 0.2 0.7 0.6 1.8 1.8 0.0 0.3 0.1 0.3 2.0 1.8 0.9 0.1 0.1 0.1 0.3 1.9 0.2 0.2 0.9 0.3 0.1 1.4 485.0 0.1 0.2 1.9 0.1 0.1 1.3 1.8 4.6 1.2 0.3 0.2 0.1 0.6 2.2 0.0 0.0 0.3 1.9 0.8 0.3 0.2 0.0 0.0 0.2 0.0 0.4 0.0 0.1 0.0 0.0 0.1 0.9 1.4 0.0 1.1 0.7 0.0 0.0 1.1 0.4 0.3 0.0 0.0 1.4 0.8 0.2 0.0 0.3 0.0 0.5 0.2 1.0 0.2 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.0 1.2 0.0 0.1 0.5 0.0 0.0 0.1 1.3 0.7 0.0 0.0 0.9 0.8 0.7 0.0 0.1 0.1 0.0 0.4 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.8 1.8 3.5 4.8 1.8 1.8 2.0 1.8 1.9 1.9 1.8 2.2 0.1 0.0 0.0 0.3 0.0 704.5 0.3 0.3 0.0 0.5 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.1 7.8 0.0 0.3 1.7 0.0 0.0 0.2 0.2 0.8 2.3 0.0 0.1 0.0 0.1 0.4 0.1 0.2 0.0 0.1 0.2 0.0 0.0 28.4 9.6 0.3 0.0 32.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.6 0.5 0.0 0.2 0.0 0.2 1.6 4.5 1.5 0.0 1004.0 1.9 0.8 0.0 0.2 0.1 CCNA2 "CCN1, CCNA" ENSG00000145386 "Cyclin A2" P20248 4 121816444-121823883 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Host-virus interaction, Mitosis" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 38.6;lymphoid tissue: 46.9;retina: 31.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 47.9;Erythroid cells: 102.1;Extravillous trophoblasts: 92.8;Plasma cells: 35.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 3.1" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basal ganglia: 3.4;white matter: 7.6" "CAB000114, HPA020626" Enhanced Enhanced Nucleoplasm,Cytosol Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cytosol" "CAB000114: AB_563675, HPA020626: AB_1847376" "unprognostic (4.02e-2)" "unprognostic (1.93e-1)" "unprognostic (7.66e-3)" "prognostic unfavorable (8.78e-4)" "unprognostic (1.25e-1)" "unprognostic (1.67e-2)" "prognostic unfavorable (9.17e-5)" "prognostic unfavorable (4.27e-4)" "unprognostic (3.92e-3)" "unprognostic (2.65e-2)" "prognostic unfavorable (4.43e-6)" "unprognostic (8.38e-3)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.65e-1)" "unprognostic (1.82e-1)" "unprognostic (6.07e-2)" "unprognostic (1.59e-1)" 1.5 1.2 2.5 11.4 2.5 38.6 2.5 3.5 4.7 4.3 2.5 9.8 10.1 2.5 0.6 8.4 2.2 1.8 1.3 2.3 2.4 1.5 1.6 1.8 25.0 2.8 2.7 3.8 0.8 0.6 2.7 10.5 2.6 1.9 11.5 31.7 1.8 0.8 0.7 6.7 9.9 4.0 2.6 4.6 4.4 6.2 2.6 46.9 1.2 0.5 24.4 2.9 3.9 3.5 177.1 45.3 120.5 51.8 6.4 16.3 98.8 119.7 52.8 156.7 115.6 99.4 106.5 161.2 31.7 63.8 55.0 58.0 154.2 71.1 128.0 77.8 70.8 129.7 56.0 96.9 1.5 197.0 88.0 4.2 5.3 65.1 38.7 24.7 95.4 84.3 187.9 156.9 126.1 63.8 251.8 113.1 95.5 109.9 49.8 114.1 233.5 78.2 44.8 34.6 51.0 53.8 63.1 76.0 32.4 89.8 63.7 81.9 56.5 72.7 109.3 77.4 115.9 98.0 112.3 181.9 41.5 197.6 82.4 0.0 0.1 0.3 0.1 0.0 0.0 0.1 0.9 0.6 0.4 0.0 0.0 0.2 0.1 0.8 0.1 0.0 3.1 0.9 2.5 2.5 3.5 4.7 2.3 2.4 2.8 2.7 2.6 2.6 2.6 3.5 0.8 0.0 1.1 1.6 5.7 2.8 1.5 5.5 1.8 2.9 1.9 1.8 0.8 0.0 1.6 0.0 12.5 47.9 1.9 4.9 0.0 0.7 9.6 0.6 2.7 3.3 1.2 102.1 3.3 0.2 92.8 6.3 9.2 2.1 0.0 18.1 4.2 0.9 25.3 0.0 4.1 7.7 8.2 6.9 3.6 2.1 0.9 3.6 1.8 2.8 0.2 1.2 0.0 4.5 5.2 0.5 3.1 1.2 35.5 3.3 1.8 0.2 2.5 14.2 0.0 0.9 6.0 10.3 17.7 24.0 1.3 8.5 6.3 1.4 19.9 2.1 CCNB1 CCNB ENSG00000134057 "Cyclin B1" P14635 5 69167135-69178245 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 52.9;lymphoid tissue: 76.2" "Cell type enriched" "Detected in many" 6 "Extravillous trophoblasts: 723.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basal ganglia: 3.0;white matter: 8.3" "Not detected" "Not detected" "CAB000115, CAB003804, HPA030741, HPA061448" Enhanced Enhanced Cytosol Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Cytosol "CAB000115: , CAB003804: AB_562272, HPA030741: AB_2673586, HPA061448: AB_2684522" "unprognostic (4.12e-2)" "unprognostic (2.75e-2)" "unprognostic (1.91e-3)" "unprognostic (4.08e-3)" "unprognostic (2.78e-1)" "unprognostic (1.39e-1)" "prognostic unfavorable (1.54e-7)" "prognostic unfavorable (3.38e-4)" "unprognostic (1.43e-2)" "unprognostic (1.63e-2)" "unprognostic (2.49e-3)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.11e-16)" "unprognostic (2.44e-1)" "unprognostic (3.73e-1)" "unprognostic (1.44e-1)" "unprognostic (5.15e-3)" 4.0 5.1 4.0 26.0 3.9 52.9 10.0 6.0 4.9 6.3 2.8 22.2 20.9 7.7 5.4 36.0 8.2 4.0 3.0 3.8 4.0 4.8 4.3 3.9 54.5 6.2 4.4 5.0 4.2 5.8 2.6 20.8 6.5 3.8 29.5 5.7 6.5 3.9 3.4 14.5 19.5 14.4 3.5 11.1 10.8 32.9 5.2 76.2 9.3 2.0 67.0 8.4 10.4 4.0 466.0 317.1 423.5 377.1 22.2 37.1 980.2 201.3 150.8 521.3 437.0 471.2 423.9 285.2 239.1 187.6 594.2 284.2 432.4 442.8 577.2 281.4 217.2 181.6 243.2 323.2 6.8 160.5 197.7 16.6 27.7 300.5 207.2 47.7 282.8 274.2 223.5 217.9 430.2 441.4 220.5 184.7 236.7 153.3 199.3 228.4 305.2 288.2 192.6 168.2 212.7 133.5 347.7 160.3 141.9 236.4 306.4 162.5 119.8 114.4 368.5 207.6 510.2 109.2 216.6 399.8 158.8 271.9 358.6 3.1 2.0 1.5 3.2 5.1 4.5 15.4 8.3 7.4 6.0 11.1 2.7 2.6 1.3 8.2 2.4 5.0 17.6 6.2 4.0 3.9 6.0 4.9 3.8 4.0 6.2 4.4 6.5 3.5 5.2 4.0 4.0 0.0 0.5 2.0 11.8 11.5 7.2 32.1 4.6 4.8 9.8 12.3 1.9 1.5 8.8 5.5 2.1 108.2 8.3 9.5 1.9 6.5 110.2 15.2 7.4 6.6 1.2 76.2 2.7 1.4 723.1 18.3 21.4 13.0 2.5 63.0 8.9 3.2 60.2 0.0 2.1 13.8 73.2 12.0 7.2 17.8 3.1 9.7 3.6 1.0 2.7 3.9 2.1 0.5 1.0 2.4 1.5 2.6 24.1 4.5 2.5 5.6 13.1 4.1 6.6 4.9 18.5 74.3 62.2 37.4 7.2 41.5 8.0 11.8 33.4 7.8 CCNB2 HsT17299 ENSG00000157456 "Cyclin B2" O95067 15 59105126-59125045 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 74.6;lymphoid tissue: 73.1;testis: 69.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 67.9;Early spermatids: 228.5;Erythroid cells: 123.6;Extravillous trophoblasts: 128.3;Spermatocytes: 288.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 5 "T-reg: 22.7" "Lineage enriched" "Detected in many" 6 "T-cells: 22.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA008873, CAB009575" Enhanced Enhanced "Golgi apparatus,Cytosol" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "Golgi apparatus" "CAB009575: AB_2072392, HPA008873: AB_1078604" "unprognostic (2.69e-2)" "unprognostic (2.25e-1)" "unprognostic (4.43e-2)" "unprognostic (1.96e-2)" "unprognostic (1.77e-1)" "unprognostic (4.65e-2)" "prognostic unfavorable (2.83e-4)" "prognostic unfavorable (4.63e-4)" "prognostic unfavorable (3.21e-5)" "unprognostic (1.09e-1)" "prognostic unfavorable (1.74e-5)" "unprognostic (4.48e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.96e-1)" "unprognostic (1.41e-1)" "unprognostic (3.98e-2)" "unprognostic (4.44e-1)" 1.0 1.1 0.4 12.2 1.1 74.6 2.9 0.7 0.7 2.9 1.1 14.3 14.1 2.6 0.3 16.1 1.1 1.9 0.7 0.6 0.7 1.1 1.4 2.2 33.0 1.3 1.0 0.8 0.7 0.2 0.3 11.4 1.0 1.6 16.8 0.3 2.8 0.4 0.7 9.4 12.0 6.4 0.7 7.1 5.6 69.4 1.1 73.1 1.0 0.4 43.7 3.6 5.6 2.2 132.5 112.1 188.6 47.1 8.5 16.6 97.5 104.8 69.9 165.2 135.6 187.8 81.1 122.1 75.4 71.8 97.2 160.1 181.4 92.6 157.8 124.1 92.4 153.1 127.3 108.1 2.5 118.1 98.6 6.3 12.6 71.4 91.9 32.7 114.1 147.0 163.1 194.5 128.2 96.5 137.9 177.2 138.6 58.5 65.2 157.5 260.0 124.4 53.3 91.9 115.2 75.9 148.9 80.2 97.3 147.9 139.4 120.4 58.5 81.6 134.4 90.5 210.5 84.2 133.2 213.8 53.6 267.1 117.9 0.0 0.1 0.7 0.1 0.0 0.3 2.1 4.6 5.0 3.0 1.7 0.0 0.1 0.8 3.6 0.1 0.1 22.7 2.1 0.4 1.1 0.7 0.7 0.6 0.7 1.3 1.0 1.0 0.7 1.1 2.2 0.3 0.0 0.6 0.0 6.8 4.8 2.8 11.5 1.8 0.2 2.5 3.3 0.5 0.0 3.2 0.0 0.0 67.9 1.6 4.1 0.0 0.7 228.5 5.3 3.1 3.9 3.0 123.6 0.7 0.2 128.3 7.2 7.1 5.9 0.0 29.9 6.1 1.1 29.9 0.0 0.8 10.1 20.3 10.6 3.3 53.5 4.4 7.9 0.0 0.0 2.4 0.2 1.0 0.0 1.4 0.4 1.9 1.9 18.7 2.3 2.1 0.0 1.8 0.3 0.0 1.0 5.7 288.7 32.1 20.3 6.1 16.3 4.4 4.1 23.4 5.0 CD163 "M130, MM130, SCARI1" ENSG00000177575 "CD163 molecule" Q86VB7 12 7470811-7503893 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Acute phase, Inflammatory response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 240.5" "Cell type enriched" "Detected in many" 4 "Kupffer cells: 1756.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 11 "classical monocyte: 76.1;myeloid DC: 65.2" "Group enriched" "Detected in many" 40 "dendritic cells: 65.2;monocytes: 76.1" "Cell line enhanced" "Detected in some" "GAMG: 1.8;HSkMC: 1.7" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "CAB002432, HPA046404, HPA051974" Enhanced Supported "Plasma membrane" "Secreted to blood" NA NA 903000000 1600000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "CAB002432: AB_563510, HPA046404: AB_2679655, HPA051974: AB_2681678" "unprognostic (1.13e-1)" "unprognostic (2.13e-1)" "unprognostic (5.02e-3)" "unprognostic (2.72e-1)" "unprognostic (6.17e-3)" "unprognostic (2.09e-1)" "unprognostic (1.02e-1)" "unprognostic (1.21e-1)" "unprognostic (2.78e-1)" "prognostic unfavorable (7.27e-4)" "unprognostic (1.04e-1)" "unprognostic (6.50e-2)" "unprognostic (1.84e-2)" "unprognostic (8.77e-2)" "unprognostic (4.95e-2)" "unprognostic (1.61e-1)" "unprognostic (1.20e-2)" 171.8 85.6 6.1 152.5 7.0 17.6 50.8 5.2 18.4 25.6 21.5 48.7 12.4 27.3 3.6 16.4 68.1 43.5 52.7 4.9 7.9 27.3 89.7 131.7 54.4 15.8 10.9 23.1 21.4 8.8 11.4 109.4 18.0 15.5 21.6 4.3 25.9 7.2 11.4 15.3 52.9 130.4 7.2 240.5 35.6 9.7 55.9 18.7 17.2 17.6 7.2 68.5 16.3 10.3 0.0 0.0 0.0 0.0 0.6 0.3 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 1.7 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.3 76.1 0.5 0.1 6.4 0.0 0.0 0.0 0.1 65.2 0.0 0.0 0.0 1.7 0.0 0.0 1.0 0.1 20.1 6.1 7.0 5.2 18.4 4.9 7.9 15.8 10.9 18.0 7.2 55.9 10.3 2.7 3.2 8.3 0.0 3.8 1.5 0.2 0.0 0.0 0.1 0.1 0.3 4.6 7.2 5.0 0.0 2.1 1.5 0.5 0.0 0.0 0.0 4.3 0.0 0.1 13.9 0.0 3.6 0.4 0.0 1.9 3.0 0.5 0.0 5.1 0.1 17.9 13.9 269.9 0.0 0.5 0.0 0.0 1756.1 30.9 6.4 5.0 387.9 0.0 2.8 41.1 0.9 1.0 0.0 0.0 0.0 0.0 1.2 1.0 0.1 0.0 0.2 1.6 0.2 118.3 1.7 4.0 3.9 2.6 0.5 1.0 3.0 1.3 0.0 0.0 0.1 CD2 SRBC ENSG00000116824 "CD2 molecule" P06729 1 116754430-116769229 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "lymphoid tissue: 249.8" "Group enriched" "Detected in many" 6 "dendritic cells: 158.3;NK-cells: 178.2;T-cells: 476.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 6 "gdT-cell: 421.8;MAIT T-cell: 403.1;memory CD4 T-cell: 610.2;memory CD8 T-cell: 714.1;naive CD4 T-cell: 316.3;naive CD8 T-cell: 486.2;NK-cell: 1108.0;T-reg: 655.2" "Group enriched" "Detected in all" 10 "NK-cells: 1108.0;T-cells: 714.1" "Group enriched" "Detected in some" 25 "HDLM-2: 224.1;JURKAT: 145.8;MOLT-4: 166.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB002430, HPA003883" Enhanced Supported "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "Nucleoplasm, Golgi apparatus" "CAB002430: AB_442057, HPA003883: AB_1846263" "prognostic favorable (4.36e-4)" "prognostic favorable (1.47e-4)" "unprognostic (3.34e-3)" "prognostic favorable (1.69e-5)" "unprognostic (1.52e-1)" "prognostic favorable (7.46e-5)" "unprognostic (9.32e-3)" "unprognostic (1.61e-2)" "prognostic favorable (3.97e-5)" "prognostic favorable (7.72e-4)" "unprognostic (4.18e-2)" "unprognostic (3.31e-1)" "prognostic unfavorable (4.82e-6)" "unprognostic (6.16e-2)" "unprognostic (6.61e-2)" "unprognostic (2.73e-2)" "unprognostic (7.63e-3)" 4.6 4.6 0.6 51.3 0.7 11.4 7.6 0.6 1.0 5.8 0.8 13.9 17.2 3.7 2.8 8.4 4.2 16.8 2.6 0.5 0.8 2.5 7.8 21.0 119.6 1.7 0.7 2.8 2.9 0.9 0.7 1.0 1.1 5.2 16.0 0.0 8.6 2.3 1.4 3.5 28.4 4.4 1.0 44.1 24.1 1.8 1.0 249.8 3.8 1.7 79.1 20.8 3.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 224.1 0.0 0.4 0.0 0.0 0.0 0.4 7.2 0.0 0.0 0.0 0.0 0.0 0.0 145.8 0.1 0.5 0.0 0.0 166.9 0.2 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.8 0.4 0.0 11.3 5.2 1.6 421.8 3.7 403.1 3.8 610.2 714.1 95.4 2.5 316.3 486.2 14.1 1108.0 2.8 21.0 655.2 565.1 0.6 0.7 0.6 1.0 0.5 0.8 1.7 0.7 1.1 1.0 1.0 1.1 5.0 3.2 17.5 0.0 12.3 5.0 0.4 0.0 2.2 0.0 4.0 4.7 2.1 0.0 2.5 3.7 0.0 0.1 158.3 0.2 0.0 0.5 23.5 1.1 1.0 2.9 3.0 24.0 0.0 0.0 0.0 2.5 10.7 0.9 5.1 0.0 8.2 1.5 0.6 0.0 0.0 0.0 0.0 10.9 16.6 7.8 0.6 19.1 1.8 1.0 15.5 0.0 178.2 0.0 0.0 0.0 0.0 0.4 42.3 0.1 0.0 1.7 0.0 0.0 0.0 2.9 4.1 0.3 0.2 0.4 3.7 0.0 476.8 0.0 0.5 0.2 CD3E ENSG00000198851 "CD3e molecule" P07766 11 118304730-118316175 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Adaptive immunity, Immunity" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 17 "lymphoid tissue: 640.4" "Group enriched" "Detected in many" 7 "dendritic cells: 213.6;NK-cells: 154.5;T-cells: 601.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 26 "gdT-cell: 490.6;MAIT T-cell: 420.8;memory CD4 T-cell: 414.4;memory CD8 T-cell: 463.5;naive CD4 T-cell: 491.7;naive CD8 T-cell: 501.3;NK-cell: 202.2;T-reg: 426.3" "Group enriched" "Detected in all" 21 "NK-cells: 202.2;T-cells: 501.3" "Group enriched" "Detected in some" 67 "JURKAT: 544.9;MOLT-4: 764.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB000010, HPA040957, HPA043955, CAB072863, CAB072864" Enhanced Supported "Endoplasmic reticulum,Golgi apparatus,Plasma membrane" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "Endoplasmic reticulum, Plasma membrane" "Golgi apparatus" "CAB000010: AB_2631163, CAB072863: AB_2665707, CAB072864: AB_2665708, HPA040957: AB_2677222, HPA043955: AB_2678747" "prognostic favorable (1.72e-4)" "prognostic favorable (1.62e-4)" "unprognostic (1.51e-2)" "prognostic favorable (2.30e-6)" "unprognostic (4.31e-2)" "prognostic favorable (1.32e-4)" "unprognostic (3.60e-3)" "unprognostic (3.85e-2)" "prognostic favorable (1.18e-4)" "unprognostic (6.11e-3)" "unprognostic (1.59e-1)" "unprognostic (3.59e-1)" "prognostic unfavorable (1.12e-5)" "unprognostic (5.46e-2)" "unprognostic (9.28e-2)" "unprognostic (3.13e-2)" "unprognostic (1.12e-2)" 6.4 5.6 0.9 85.8 1.1 36.7 6.7 0.9 1.2 7.1 1.3 15.3 22.0 5.8 4.6 9.5 5.4 20.1 3.8 0.7 1.0 3.5 9.7 23.0 209.6 1.8 0.9 3.8 2.2 0.7 1.0 1.6 1.4 6.6 19.3 0.0 11.6 3.0 1.9 5.4 36.4 5.1 1.2 78.9 24.4 1.7 1.3 640.4 5.3 1.6 147.0 24.8 4.9 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 544.9 0.9 2.0 0.0 0.0 764.9 0.6 0.3 0.0 0.0 0.2 0.1 1.0 0.0 0.0 0.1 0.1 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.2 0.0 1.6 8.0 9.8 0.0 0.6 0.0 16.4 1.8 2.4 490.6 1.3 420.8 1.6 414.4 463.5 1.5 2.1 491.7 501.3 12.2 202.2 2.0 8.6 426.3 333.0 0.9 1.1 0.9 1.2 0.7 1.0 1.8 0.9 1.4 1.2 1.3 1.6 4.9 0.0 8.6 0.0 12.9 5.2 0.3 0.0 0.0 0.0 3.8 4.8 0.3 0.0 0.6 1.8 0.0 0.2 213.6 0.4 0.0 0.2 7.0 0.5 0.9 2.5 0.0 6.9 0.1 0.0 0.0 5.3 24.5 0.9 7.6 0.0 8.9 2.4 0.3 0.0 0.1 0.0 0.0 7.6 8.3 0.2 0.0 12.6 12.4 1.0 8.4 0.0 154.5 0.0 0.1 0.0 1.1 0.0 41.4 0.1 0.2 2.1 0.0 0.0 0.0 1.3 2.7 0.0 0.0 1.6 5.4 0.3 601.4 0.0 0.6 0.3 CD96 TACTILE ENSG00000153283 "CD96 molecule" P40200 3 111292719-111665750 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 61.8" "Group enriched" "Detected in many" 4 "dendritic cells: 96.8;NK-cells: 58.7;T-cells: 199.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "gdT-cell: 74.0;MAIT T-cell: 117.2;memory CD4 T-cell: 67.0;memory CD8 T-cell: 85.3;naive CD4 T-cell: 68.7;naive CD8 T-cell: 81.8;NK-cell: 79.5;T-reg: 47.4" "Group enriched" "Detected in many" 5 "NK-cells: 79.5;T-cells: 117.2" "Cell line enhanced" "Detected in some" "HEL: 15.9;JURKAT: 18.2;MOLT-4: 68.7;RT4: 58.2;U-937: 59.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA066754 Enhanced NA NA 85000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "HPA066754: AB_2685714" "unprognostic (1.06e-3)" "unprognostic (3.95e-3)" "unprognostic (4.16e-3)" "unprognostic (1.91e-5)" "unprognostic (4.72e-3)" "prognostic favorable (5.52e-4)" "unprognostic (2.12e-2)" "unprognostic (3.48e-2)" "unprognostic (6.06e-2)" "unprognostic (4.84e-3)" "unprognostic (2.44e-2)" "unprognostic (2.77e-1)" "prognostic unfavorable (2.02e-6)" "unprognostic (3.12e-1)" "unprognostic (4.42e-2)" "unprognostic (3.90e-2)" "prognostic favorable (5.23e-5)" 5.2 1.7 0.7 12.2 0.8 16.0 2.8 1.2 1.0 3.1 1.8 5.0 6.0 2.6 0.9 1.8 1.9 5.8 0.8 0.8 0.8 1.6 3.7 8.3 26.9 1.8 0.7 0.9 0.4 0.2 0.7 1.0 1.2 2.1 5.9 0.1 2.7 1.1 0.4 1.0 10.1 1.4 0.7 12.8 6.8 0.8 1.2 61.8 3.9 0.1 20.2 11.8 2.6 2.2 0.1 0.0 0.2 0.1 0.2 0.0 0.8 0.0 0.1 0.0 0.0 0.3 1.6 0.3 0.3 0.0 0.0 0.7 0.1 0.1 0.0 0.2 0.0 15.9 0.2 0.2 0.0 0.8 1.3 0.0 0.0 0.1 0.1 1.2 0.0 18.2 0.3 2.0 0.0 0.0 68.7 0.2 0.6 0.0 0.0 0.1 1.9 0.5 0.6 58.2 0.1 0.0 0.2 0.9 0.1 0.3 0.3 0.2 0.0 0.3 1.1 0.3 0.1 5.6 1.9 0.0 0.3 59.0 12.2 2.3 0.5 15.6 74.0 0.3 117.2 10.8 67.0 85.3 0.3 18.8 68.7 81.8 2.7 79.5 0.7 0.5 47.4 46.4 0.7 0.8 1.2 1.0 0.8 0.8 1.8 0.7 1.2 0.7 1.2 2.2 1.5 19.2 19.0 0.0 12.5 3.2 0.8 0.1 1.2 1.6 1.6 1.4 1.0 0.0 9.3 1.8 0.0 0.6 96.8 0.8 0.0 0.1 0.8 2.1 0.8 3.0 0.0 9.3 0.7 0.0 0.2 4.3 8.6 1.6 16.4 0.4 2.2 0.9 0.2 0.0 0.4 0.7 0.0 5.0 6.7 1.1 0.3 6.7 3.6 6.5 2.9 0.5 58.7 0.0 0.1 0.0 1.3 0.0 29.6 0.3 0.0 0.4 1.7 2.1 0.0 0.8 1.0 0.4 0.7 0.6 3.1 1.9 199.9 0.2 0.5 0.6 CDC20 "CDC20A, p55CDC" ENSG00000117399 "Cell division cycle 20" Q12834 1 43358981-43363203 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Differentiation, Mitosis, Neurogenesis, Ubl conjugation pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 53.9;lymphoid tissue: 52.6;testis: 49.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 65.0;Early spermatids: 135.0;Erythroid cells: 96.0;Extravillous trophoblasts: 146.2;Spermatocytes: 126.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 7 "memory B-cell: 4.2;memory CD4 T-cell: 3.2;memory CD8 T-cell: 3.5;NK-cell: 9.5;T-reg: 11.6" "Group enriched" "Detected in many" 9 "B-cells: 4.2;NK-cells: 9.5;T-cells: 11.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "CAB004525, HPA045842, HPA055288" Enhanced Enhanced Nucleoplasm,Cytosol Yes Yes "Cluster 15: NK-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cytosol" "CAB004525: AB_628089, HPA045842: AB_2679470, HPA055288: AB_2682773" "unprognostic (1.66e-2)" "unprognostic (1.09e-1)" "unprognostic (1.73e-2)" "unprognostic (2.14e-3)" "unprognostic (1.58e-1)" "unprognostic (1.09e-1)" "prognostic unfavorable (4.00e-8)" "unprognostic (9.06e-3)" "unprognostic (1.17e-2)" "unprognostic (1.23e-2)" "prognostic unfavorable (1.32e-4)" "unprognostic (8.55e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.84e-2)" "unprognostic (2.28e-1)" "unprognostic (2.01e-1)" "unprognostic (1.29e-2)" 1.6 1.5 0.6 16.2 1.1 53.9 5.2 0.8 1.3 3.5 0.4 14.8 13.7 2.3 2.5 27.2 1.7 1.2 0.9 0.7 1.1 2.3 1.7 2.5 32.6 1.3 1.1 0.7 0.6 0.2 0.3 9.7 1.1 0.8 16.0 0.2 4.4 0.7 0.3 11.3 12.2 7.3 0.8 11.7 7.0 49.1 1.7 52.6 1.7 0.2 50.8 3.3 7.0 1.3 311.9 148.2 202.8 133.4 6.9 17.6 193.5 140.3 125.0 400.0 211.4 234.5 250.9 178.3 80.1 130.1 140.6 212.8 225.3 267.9 331.5 140.8 165.6 261.4 143.6 147.3 2.1 184.3 91.4 6.0 12.4 278.2 249.6 35.1 172.2 167.5 120.2 119.3 184.0 120.4 179.2 113.5 257.2 147.0 196.9 255.8 277.9 112.9 98.5 81.3 119.2 58.9 248.1 165.8 76.6 154.9 116.3 231.7 90.2 118.9 276.2 133.7 445.0 90.6 86.7 185.7 85.2 227.6 181.6 0.0 0.1 0.0 0.3 0.0 0.0 4.2 3.2 3.5 0.9 0.9 0.1 0.3 0.7 9.5 0.0 0.2 11.6 2.8 0.6 1.1 0.8 1.3 0.7 1.1 1.3 1.1 1.1 0.8 1.7 1.3 2.1 0.0 1.1 0.0 12.2 10.5 3.8 17.6 6.2 0.5 6.4 9.7 0.7 1.5 4.8 0.0 0.0 65.0 2.8 16.9 0.0 2.2 135.0 14.6 2.4 4.5 0.0 96.0 0.2 0.4 146.2 9.3 11.7 4.6 0.0 46.5 7.9 1.3 37.4 0.0 0.0 18.5 24.4 6.2 7.5 18.5 2.8 9.3 0.0 0.0 1.8 0.3 0.0 0.0 1.6 0.7 0.5 1.9 34.4 2.7 3.2 3.1 8.3 2.9 0.0 1.0 25.4 126.5 39.8 47.3 8.4 10.7 5.1 1.6 37.5 7.4 CDC25C "CDC25, PPP1R60" ENSG00000158402 "Cell division cycle 25C" P30307 5 138285269-138338355 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Host-virus interaction, Mitosis" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.8;lymphoid tissue: 8.9;testis: 18.1" "Cell type enhanced" "Detected in many" "Early spermatids: 41.4;Late spermatids: 42.1;Spermatocytes: 53.6;Spermatogonia: 13.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "CAB003800, HPA066991" Approved Enhanced "Nuclear speckles" No Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear speckles" "CAB003800: AB_562081, HPA066991: AB_2685760" "unprognostic (2.45e-3)" "unprognostic (5.89e-3)" "prognostic favorable (2.49e-4)" "unprognostic (9.72e-3)" "unprognostic (2.17e-1)" "unprognostic (1.53e-1)" "prognostic unfavorable (3.03e-6)" "prognostic unfavorable (4.38e-4)" "unprognostic (5.56e-2)" "unprognostic (2.08e-1)" "unprognostic (1.70e-3)" "unprognostic (1.00e-1)" "unprognostic (0.00e+0)" "unprognostic (5.04e-2)" "unprognostic (1.43e-1)" "unprognostic (2.59e-1)" "unprognostic (3.06e-1)" 0.2 0.2 0.2 2.1 0.2 5.8 0.7 0.3 0.3 0.3 0.2 3.4 3.0 0.4 0.2 1.4 0.2 0.2 0.1 0.2 0.2 0.1 0.5 0.3 3.2 0.2 0.3 0.0 0.4 0.1 0.1 1.2 0.2 0.2 4.1 0.1 0.3 0.1 0.0 1.4 3.0 0.8 0.1 0.9 1.1 18.1 0.2 8.9 0.1 0.0 4.6 0.5 0.5 0.2 27.9 11.0 38.4 28.9 0.9 3.6 9.9 16.4 17.5 36.2 50.3 27.3 52.8 13.3 13.8 10.1 40.5 14.9 31.7 25.9 34.9 11.1 21.5 9.6 15.0 21.2 0.3 6.3 10.0 0.8 0.9 22.0 18.0 3.8 24.6 28.9 14.8 24.2 22.9 15.5 19.3 16.7 9.7 22.3 12.2 11.9 34.2 15.0 6.4 8.4 19.2 11.9 36.8 11.0 16.9 32.6 18.7 13.9 7.2 19.9 16.8 13.9 26.5 15.0 13.4 13.0 8.3 14.3 15.6 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.6 0.1 0.2 0.2 0.3 0.3 0.2 0.2 0.2 0.3 0.2 0.1 0.2 0.2 0.1 0.0 0.0 1.3 0.9 0.6 0.3 1.1 1.8 0.0 0.9 0.8 0.3 0.0 0.2 0.0 0.0 5.0 0.5 1.8 0.0 0.1 41.4 0.4 0.9 0.6 0.0 9.5 1.3 0.0 6.9 1.1 3.6 1.2 0.0 5.5 1.4 0.4 2.7 0.0 1.0 3.9 2.0 0.6 0.5 42.1 1.8 1.2 0.0 1.0 0.6 0.0 0.0 1.0 0.3 0.0 1.4 0.4 4.5 0.3 0.9 0.1 0.1 0.0 0.0 0.2 0.9 53.6 13.0 4.3 0.4 1.4 0.6 0.2 4.9 0.6 CDCA2 "PPP1R81, Repo-Man" ENSG00000184661 "Cell division cycle associated 2" Q69YH5 8 25459199-25507911 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "bone marrow: 6.5;lymphoid tissue: 11.4;testis: 19.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 23.3;Early spermatids: 49.9;Erythroid cells: 19.0;Late spermatids: 24.2;Spermatocytes: 66.6;Spermatogonia: 27.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA026293, HPA030049" Enhanced Supported Nucleoplasm Yes Yes "Cluster 15: NK-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA026293: AB_1846384, HPA030049: AB_10600862" "unprognostic (2.12e-1)" "unprognostic (4.75e-3)" "prognostic favorable (9.62e-4)" "unprognostic (2.92e-2)" "unprognostic (9.69e-2)" "unprognostic (3.56e-2)" "unprognostic (2.50e-5)" "unprognostic (1.47e-3)" "unprognostic (6.06e-2)" "unprognostic (2.91e-3)" "unprognostic (1.32e-3)" "unprognostic (1.99e-1)" "prognostic unfavorable (2.30e-14)" "unprognostic (1.36e-2)" "unprognostic (4.02e-1)" "unprognostic (1.91e-1)" "unprognostic (5.30e-2)" 0.2 0.0 0.0 2.6 0.0 6.5 0.6 0.1 0.0 0.2 0.1 1.9 1.6 0.3 0.0 1.4 0.1 0.3 0.3 0.0 0.1 0.0 0.1 0.2 5.3 0.2 0.2 0.0 0.0 0.0 0.0 1.2 0.2 0.1 2.2 0.1 0.2 0.0 0.0 1.1 1.8 0.8 0.0 0.8 0.9 19.4 0.3 11.4 0.1 0.1 6.7 0.6 0.3 0.1 36.5 30.2 29.4 24.2 2.3 4.5 20.2 37.7 22.6 32.9 32.4 25.7 15.8 42.6 16.0 16.2 34.6 31.6 42.9 20.0 48.5 16.2 12.0 43.2 22.4 15.2 0.6 18.4 19.4 2.5 1.0 23.5 15.8 3.3 24.5 24.5 33.6 45.8 30.6 13.9 54.5 8.7 31.0 24.1 14.5 26.3 33.4 15.2 9.2 18.7 12.0 13.3 33.3 16.1 14.3 14.7 17.4 9.4 16.6 23.9 39.3 44.7 35.6 7.1 16.5 44.4 17.7 24.3 40.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.2 0.2 0.0 0.3 0.1 0.2 0.0 1.1 0.0 2.7 1.1 0.5 1.7 0.0 0.7 0.9 0.8 23.3 0.0 0.2 0.0 0.0 7.2 0.5 1.8 0.0 0.2 49.9 0.8 1.2 1.1 0.0 19.0 0.2 0.0 13.4 2.5 4.1 1.4 0.0 8.8 1.1 0.1 4.1 0.0 0.1 1.3 0.0 2.9 0.6 24.2 1.2 2.1 0.0 0.0 0.6 0.1 2.1 0.5 0.6 0.2 0.1 0.0 15.8 0.5 0.5 1.2 0.9 0.5 13.1 0.1 2.1 66.6 27.8 10.7 0.9 1.6 2.9 1.3 3.6 0.5 CDCA3 "GRCC8, TOME-1" ENSG00000111665 "Cell division cycle associated 3" Q99618 12 6844793-6851292 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 30.5;retina: 66.3" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 56.3;Erythroid cells: 46.5;Extravillous trophoblasts: 74.1;Proximal enterocytes: 65.5;Spermatocytes: 71.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "T-reg: 4.3" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA026587 Approved Cytosol NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA026587: AB_1846386" "unprognostic (3.05e-1)" "unprognostic (1.32e-1)" "unprognostic (9.85e-2)" "unprognostic (1.63e-2)" "unprognostic (2.42e-1)" "unprognostic (7.41e-2)" "prognostic unfavorable (6.51e-5)" "prognostic unfavorable (9.77e-5)" "unprognostic (3.88e-2)" "unprognostic (1.27e-1)" "unprognostic (1.80e-3)" "unprognostic (8.81e-2)" "unprognostic (0.00e+0)" "unprognostic (1.22e-1)" "unprognostic (1.09e-1)" "unprognostic (2.11e-1)" "unprognostic (4.94e-2)" 1.2 2.6 0.7 7.3 0.5 16.0 1.2 1.0 1.0 4.4 0.3 6.1 20.7 2.9 0.4 9.0 1.9 1.1 2.8 0.6 0.6 1.6 1.6 1.7 17.2 0.7 0.7 4.6 1.1 0.4 8.6 4.7 0.6 3.1 7.8 66.3 2.5 0.3 0.5 6.3 18.5 3.0 0.4 4.6 3.2 21.4 0.6 30.5 1.8 0.2 23.4 2.2 4.0 0.5 106.8 88.8 81.0 45.1 4.3 6.8 95.0 71.7 46.4 119.5 83.3 142.7 86.9 64.9 8.6 54.9 86.9 71.0 53.3 55.0 117.0 97.2 60.9 56.8 58.9 81.7 0.5 41.3 47.2 3.1 3.9 63.0 34.6 27.9 50.9 44.2 47.8 36.4 116.7 94.1 60.0 46.0 86.2 75.8 62.3 57.6 68.5 34.3 40.2 36.4 12.2 23.6 61.8 53.5 18.7 87.0 21.9 38.6 22.3 52.6 67.2 35.0 117.2 19.7 21.5 104.2 25.4 53.6 92.0 0.0 0.2 0.0 0.1 0.1 0.3 0.7 0.7 0.8 0.2 0.2 0.2 0.4 0.2 0.4 0.3 1.1 4.3 0.5 0.7 0.5 1.0 1.0 0.6 0.6 0.7 0.7 0.6 0.4 0.6 0.5 0.7 0.0 0.5 0.7 4.1 2.9 1.7 5.0 2.2 12.3 1.9 2.5 1.2 1.5 1.1 0.0 56.3 29.5 0.9 6.9 0.0 1.1 12.4 1.8 2.3 1.7 1.2 46.5 0.5 0.4 74.1 5.2 4.6 2.3 4.5 15.2 3.9 1.6 19.3 6.7 0.6 11.9 4.1 4.0 3.1 6.8 1.8 3.5 0.0 1.0 1.1 1.1 1.0 0.5 0.5 0.4 4.0 0.4 19.2 1.4 65.5 0.9 0.4 18.0 6.6 0.5 8.3 71.5 14.8 12.6 1.8 8.5 4.6 1.4 17.4 2.6 CDCA8 "BOR, DasraB, FLJ12042, MESRGP" ENSG00000134690 "Cell division cycle associated 8" Q53HL2 1 37692481-37709719 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 33.5;lymphoid tissue: 38.8;testis: 22.5" "Cell type enhanced" "Detected in many" "Erythroid cells: 34.1;Extravillous trophoblasts: 26.0;Spermatocytes: 76.8;Spermatogonia: 42.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA028120, HPA028258, HPA028783, CAB040294" Enhanced Supported "Nucleoplasm,Nucleoli,Cytokinetic bridge" Yes Yes "Cluster 27: Non-specific - Gene expression" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoli "Nucleoplasm, Cytokinetic bridge" "CAB040294: , HPA028120: AB_10670556, HPA028258: AB_10669864, HPA028783: AB_10671092" "unprognostic (8.36e-2)" "unprognostic (2.00e-1)" "unprognostic (8.39e-2)" "unprognostic (7.75e-3)" "unprognostic (2.34e-1)" "unprognostic (5.42e-2)" "prognostic unfavorable (4.93e-10)" "unprognostic (4.30e-3)" "prognostic unfavorable (6.04e-4)" "unprognostic (3.00e-1)" "prognostic unfavorable (8.32e-4)" "unprognostic (3.78e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (6.39e-3)" "unprognostic (2.99e-1)" "unprognostic (3.18e-1)" "unprognostic (1.67e-1)" 1.0 1.1 0.7 7.9 1.0 33.5 2.0 0.2 0.9 1.7 0.0 9.4 8.3 1.3 1.8 9.2 1.0 1.1 0.6 0.5 0.4 0.8 1.3 1.5 19.5 0.6 0.4 0.6 0.8 0.5 0.6 4.4 0.5 0.7 11.3 1.9 1.8 0.5 0.3 6.3 7.3 2.8 0.3 4.9 4.9 22.5 0.6 38.8 0.6 0.5 22.7 2.0 2.9 0.7 108.5 45.5 84.4 62.1 3.6 7.0 57.2 79.6 39.5 137.2 96.6 71.9 78.8 130.2 31.5 50.5 54.5 59.4 97.8 52.4 141.9 86.8 44.9 116.8 49.2 57.3 0.8 113.8 58.4 2.8 3.8 77.1 67.3 15.3 60.9 91.1 100.7 135.6 99.1 47.7 106.1 68.9 98.8 61.7 62.8 102.2 115.6 74.4 31.0 43.8 75.4 33.3 87.5 40.6 52.4 71.7 60.1 42.4 37.3 67.8 70.6 39.2 126.0 91.4 128.1 176.3 31.6 104.7 79.6 0.0 0.7 1.3 1.5 1.6 2.8 1.7 3.6 2.2 0.7 1.4 1.1 2.3 3.0 4.1 3.9 1.2 5.9 1.7 0.7 1.0 0.2 0.9 0.5 0.4 0.6 0.4 0.5 0.3 0.6 0.7 0.8 0.0 0.5 1.3 4.8 3.3 0.8 2.4 1.8 1.3 1.9 1.5 0.7 2.8 0.4 0.0 0.0 17.1 1.9 12.4 0.0 1.2 1.0 1.7 1.6 1.9 3.6 34.1 1.2 0.6 26.0 2.9 6.6 2.5 0.0 12.0 3.6 1.0 11.6 1.7 0.9 8.2 2.0 3.5 1.9 2.8 1.5 3.7 1.8 0.0 1.6 0.1 2.1 0.5 0.9 2.4 4.0 1.2 15.8 1.3 1.9 0.6 4.7 1.0 19.7 0.2 6.3 76.8 42.0 17.1 2.7 2.9 5.5 1.2 13.2 1.2 CDCP1 "CD318, SIMA135" ENSG00000163814 "CUB domain containing protein 1" Q9H5V8 3 45082277-45146422 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 37.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 121.2;Basal respiratory cells: 92.6;Pancreatic endocrine cells: 137.1;Urothelial cells: 117.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "myeloid DC: 2.3;NK-cell: 4.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 94.9;HBEC3-KT: 109.0;hTEC/SVTERT24-B: 265.2;hTERT-HME1: 177.9;PC-3: 89.7;RPTEC TERT1: 81.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA010978, HPA010979, CAB025637" Enhanced "Intracellular and membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "CAB025637: , HPA010978: AB_1846403, HPA010979: AB_1846401" "unprognostic (9.31e-2)" "unprognostic (4.50e-2)" "unprognostic (1.67e-2)" "unprognostic (2.66e-1)" "unprognostic (1.11e-2)" "unprognostic (1.51e-3)" "unprognostic (2.94e-2)" "prognostic unfavorable (1.41e-5)" "unprognostic (2.15e-1)" "unprognostic (1.00e-1)" "prognostic unfavorable (1.48e-4)" "unprognostic (2.14e-2)" "unprognostic (9.98e-3)" "unprognostic (3.59e-2)" "unprognostic (2.99e-1)" "unprognostic (1.21e-1)" "unprognostic (1.34e-1)" 2.3 0.5 0.4 4.4 0.7 0.9 5.6 0.4 1.2 8.5 12.8 17.4 17.7 3.2 9.2 37.2 4.0 6.2 0.5 0.7 0.7 4.8 0.8 8.2 0.8 1.4 0.8 0.3 7.9 1.4 1.2 2.2 1.3 5.1 17.0 0.2 12.6 5.6 0.3 23.3 15.1 3.1 1.1 0.7 16.5 0.6 3.6 0.6 7.7 0.0 5.8 9.7 16.4 2.6 52.2 15.1 0.0 0.2 0.1 2.4 12.1 9.7 1.6 4.4 4.1 21.3 94.9 0.0 11.8 2.9 2.5 40.5 0.3 109.0 8.9 0.0 0.1 0.1 16.4 0.1 8.1 0.1 3.6 3.7 56.1 265.2 177.9 16.0 1.0 0.1 31.1 0.2 13.8 0.1 0.1 0.9 7.4 24.7 89.7 0.0 0.0 8.6 81.1 40.7 3.4 0.1 20.1 5.0 0.1 4.8 22.9 0.4 4.6 0.2 0.2 3.3 0.2 0.1 0.1 0.1 1.5 1.1 1.1 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.3 0.0 0.1 0.0 0.9 4.2 0.0 0.0 0.0 0.2 0.4 0.7 0.4 1.2 0.7 0.7 1.4 0.8 1.3 1.1 3.6 2.6 0.1 3.2 13.1 0.3 0.3 121.2 83.3 92.6 50.7 0.0 12.9 6.6 0.5 14.3 57.7 9.2 0.0 5.8 0.3 76.6 0.0 78.6 0.1 36.5 6.3 1.9 37.6 0.4 2.0 71.6 7.5 4.6 37.8 59.3 8.8 0.1 0.0 0.0 10.8 0.0 0.4 37.9 18.3 7.9 37.6 0.5 3.1 13.4 3.6 0.0 10.7 0.0 0.0 1.0 0.3 137.1 34.9 0.0 2.5 75.8 30.8 0.0 56.6 0.0 0.0 0.4 3.6 0.0 0.4 59.8 75.0 3.3 1.8 13.5 28.9 117.4 CDK1 "CDC2, CDC28A" ENSG00000170312 "Cyclin dependent kinase 1" P06493 10 60778331-60794852 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Apoptosis, Biological rhythms, Cell cycle, Cell division, Host-virus interaction, Mitosis" "Host cell receptor for virus entry, Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 53.2;lymphoid tissue: 74.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 80.9;Erythroid cells: 209.6;Extravillous trophoblasts: 144.6;Spermatocytes: 110.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "NK-cell: 3.2;T-reg: 3.4" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003387, CAB003799, CAB079974" Enhanced Supported Nucleoplasm,Cytosol NA Yes 51000 "Cluster 15: NK-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cytosol" "CAB003799: AB_344898, CAB079974: , HPA003387: AB_1846356" "unprognostic (6.34e-2)" "prognostic favorable (8.81e-4)" "unprognostic (1.90e-1)" "unprognostic (6.82e-2)" "unprognostic (6.67e-2)" "unprognostic (3.83e-2)" "prognostic unfavorable (1.10e-6)" "prognostic unfavorable (7.88e-4)" "unprognostic (1.30e-2)" "unprognostic (1.30e-1)" "prognostic unfavorable (4.15e-6)" "unprognostic (1.80e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.27e-1)" "unprognostic (2.75e-1)" "unprognostic (2.13e-1)" "unprognostic (1.60e-1)" 3.8 1.8 0.9 17.0 1.0 53.2 7.4 0.9 1.5 5.2 0.9 17.6 16.3 7.1 12.2 17.5 3.7 4.3 1.4 0.9 1.0 3.1 3.2 4.7 40.6 1.2 1.2 2.3 0.8 2.5 4.1 19.4 1.1 1.7 20.8 1.3 3.2 5.2 1.4 13.2 14.5 8.0 0.9 9.0 10.1 25.1 1.4 74.0 3.6 2.2 47.5 7.1 6.9 1.0 249.9 93.5 241.1 96.0 15.4 23.6 99.0 183.8 132.7 218.8 209.0 218.9 213.7 226.2 69.6 50.6 79.6 149.9 166.2 106.8 225.8 162.3 121.1 119.4 84.4 128.1 2.8 184.5 117.6 4.7 10.4 142.1 137.0 49.6 133.3 146.2 185.1 270.3 246.9 66.3 234.0 131.1 106.6 149.3 193.1 199.7 224.5 111.3 84.3 81.4 112.7 98.7 123.5 184.9 96.3 130.0 199.9 111.5 55.4 92.8 197.9 99.1 255.8 104.9 180.8 205.6 79.9 203.5 117.6 0.0 0.0 0.0 0.3 0.1 0.2 0.5 0.7 1.3 0.3 0.4 0.2 0.7 0.0 3.2 0.1 0.9 3.4 0.9 0.9 1.0 0.9 1.5 0.9 1.0 1.2 1.2 1.1 0.9 1.4 1.0 7.7 0.0 3.2 0.3 7.1 39.8 5.4 29.9 2.8 1.1 5.3 6.1 0.8 0.0 10.2 18.4 0.0 80.9 3.6 8.9 3.9 0.8 18.7 10.8 6.2 10.5 3.0 209.6 0.4 0.0 144.6 13.3 13.3 9.4 0.0 51.5 7.5 1.3 57.2 0.0 0.2 14.6 30.5 20.5 18.1 10.4 2.1 16.5 1.8 1.9 1.0 1.0 3.1 0.0 0.1 0.4 0.7 0.7 32.1 4.3 2.2 3.0 17.6 0.7 0.0 0.5 24.6 110.0 39.6 33.8 18.6 22.0 10.3 2.1 26.6 10.4 CDKN3 "CDI1, KAP" ENSG00000100526 "Cyclin dependent kinase inhibitor 3" Q16667 14 54396849-54420218 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle" "Hydrolase, Protein phosphatase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 207.0" "Cell type enhanced" "Detected in many" "Early spermatids: 2630.9;Late spermatids: 659.4;Spermatocytes: 606.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 18.8" "Group enriched" "Detected in all" 6 "NK-cells: 6.4;T-cells: 18.8" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB005285, HPA039311, HPA058874" Enhanced Cytosol NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" Cytosol "CAB005285: AB_2078884, HPA039311: , HPA058874: AB_2683842" "unprognostic (3.46e-2)" "unprognostic (9.95e-2)" "unprognostic (5.79e-2)" "unprognostic (6.78e-3)" "unprognostic (2.73e-1)" "unprognostic (6.08e-2)" "unprognostic (1.51e-3)" "prognostic unfavorable (4.52e-4)" "unprognostic (2.50e-3)" "unprognostic (2.85e-3)" "prognostic unfavorable (7.46e-4)" "unprognostic (5.89e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.71e-1)" "unprognostic (7.30e-2)" "unprognostic (7.92e-2)" "unprognostic (4.31e-2)" 3.4 1.6 2.8 12.2 2.7 43.4 3.4 5.0 4.2 2.2 3.4 13.9 12.4 2.8 0.4 10.2 1.3 2.9 5.3 2.9 3.1 2.0 2.4 2.1 28.4 2.5 2.7 1.3 1.1 0.5 1.6 6.7 3.3 1.6 16.9 2.6 3.3 0.7 3.0 5.9 12.6 7.4 2.1 4.9 5.0 207.0 3.5 30.9 1.7 4.1 30.0 5.8 4.1 2.6 276.7 102.5 74.0 78.2 12.5 15.3 46.5 63.1 97.0 135.8 146.9 81.8 136.5 139.9 44.4 96.7 135.9 195.9 114.6 78.3 245.6 169.5 59.3 65.8 69.0 126.8 10.1 86.2 47.6 5.4 4.9 84.3 138.3 44.4 88.4 129.8 36.1 162.2 159.8 186.9 118.1 67.9 27.9 254.7 216.4 72.7 66.6 29.7 70.5 56.9 30.6 42.0 118.7 67.4 52.5 54.6 142.9 69.4 33.0 59.2 195.8 91.7 155.0 38.6 47.4 91.4 98.6 120.4 110.9 0.0 1.3 1.3 1.6 1.7 0.7 2.1 5.5 4.8 1.8 0.9 2.9 2.3 1.0 6.4 1.2 1.5 18.8 3.1 2.8 2.7 5.0 4.2 2.9 3.1 2.5 2.7 3.3 2.1 3.5 2.6 1.4 0.0 0.0 0.7 10.5 9.3 4.3 9.7 4.6 3.2 6.4 11.6 9.7 0.0 2.4 1.8 2.1 42.6 2.7 7.3 0.0 3.5 2630.9 2.7 3.5 6.8 7.8 125.5 2.5 2.4 35.0 10.2 9.2 3.5 7.0 31.3 6.1 3.1 37.7 5.0 3.9 17.9 4.1 9.8 8.8 659.4 21.5 8.9 1.8 1.0 2.9 1.7 0.0 0.0 0.2 1.9 7.2 10.5 41.0 4.0 3.4 2.8 0.2 2.9 0.0 3.0 20.5 606.9 39.8 22.5 6.5 4.1 8.3 3.9 31.2 5.3 CDSN D6S586E ENSG00000204539 Corneodesmosin 6 31115087-31120446 "Human disease related genes, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 104 "skin 1: 696.5" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 2.6;Gastric mucus-secreting cells: 2.0;Glandular and luminal cells: 7.1;granulocytes: 4.5;Suprabasal keratinocytes: 5.3" "Group enriched" "Detected in some" 8 "head and neck cancer: 2.4;melanoma: 2.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 7 "A-431: 1.6" "Region enhanced" "Detected in some" "cerebral cortex: 1.5" "Not detected" "Not detected" "HPA044730, HPA054184" Enhanced "Secreted in other tissues" NA NA "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "HPA044730: AB_10964923, HPA054184: AB_2682409" "unprognostic (1.46e-1)" "unprognostic (6.96e-2)" "unprognostic (1.20e-1)" "unprognostic (1.85e-1)" "unprognostic (3.44e-2)" "unprognostic (8.80e-2)" "unprognostic (8.13e-2)" "unprognostic (3.92e-4)" "unprognostic (3.92e-3)" "unprognostic (1.74e-4)" "unprognostic (6.34e-2)" "unprognostic (2.75e-1)" "unprognostic (2.22e-1)" 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.9 0.0 0.1 0.0 0.1 3.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.7 696.5 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 6.6 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.9 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.9 0.4 2.6 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.1 2.0 7.1 4.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.2 1.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 5.3 0.0 0.0 0.0 0.0 0.2 CEACAM1 "BGP, BGP1, CD66a" ENSG00000079385 "CEA cell adhesion molecule 1" P13688 19 42507304-42561234 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 246.3" "Group enriched" "Detected in many" 5 "Basal prostatic cells: 335.2;Distal enterocytes: 731.7;Paneth cells: 585.4;Prostatic glandular cells: 244.9;Urothelial cells: 618.9" "Cancer enhanced" "Detected in many" "colorectal cancer: 43.3" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 10 "eosinophil: 43.6;neutrophil: 26.3" "Lineage enriched" "Detected in many" 13 "granulocytes: 43.6" "Group enriched" "Detected in many" 5 "CAPAN-2: 30.6;Hep G2: 101.0;OE19: 80.9;RT4: 59.2;SK-MEL-30: 67.4" "CAB002146, HPA011041" Enhanced "Intracellular and membrane" NA NA 130000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 37: Intestine - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB002146: AB_563614, HPA011041: AB_1078481" "unprognostic (7.13e-3)" "unprognostic (2.15e-1)" "unprognostic (2.67e-2)" "prognostic favorable (6.32e-7)" "unprognostic (3.04e-1)" "unprognostic (1.80e-3)" "unprognostic (1.21e-1)" "unprognostic (4.45e-2)" "unprognostic (4.43e-1)" "unprognostic (5.46e-3)" "unprognostic (4.87e-2)" "unprognostic (4.03e-1)" "unprognostic (1.92e-2)" "unprognostic (1.88e-1)" "unprognostic (1.06e-1)" "unprognostic (7.55e-2)" "unprognostic (5.52e-3)" 11.9 10.6 1.3 31.1 0.8 74.5 13.3 3.2 1.8 16.4 0.0 246.3 53.3 11.1 3.9 64.9 6.0 7.4 4.0 1.9 0.0 31.9 60.5 6.8 4.3 0.4 0.1 1.1 2.4 1.7 3.8 33.1 0.5 20.2 141.2 0.6 58.9 10.3 2.7 3.3 51.0 13.1 0.0 7.9 19.9 3.7 0.2 2.3 3.1 3.1 21.5 37.0 29.2 0.0 0.6 5.6 0.3 0.3 0.0 0.0 14.4 0.0 0.2 1.0 0.5 2.3 30.6 1.7 12.2 0.0 3.2 0.8 0.0 7.9 0.4 0.1 0.5 0.3 0.2 101.0 1.7 0.2 13.3 0.0 0.1 0.1 0.1 0.0 0.7 1.4 0.0 5.0 0.0 3.2 0.3 0.2 0.9 80.9 1.7 2.6 0.0 1.3 0.6 59.2 0.5 0.2 0.0 0.2 67.4 7.3 0.3 0.0 2.1 0.3 1.2 1.4 0.5 1.8 0.0 3.7 0.2 0.4 1.0 0.8 0.0 43.6 0.1 1.7 0.3 3.3 0.9 0.4 0.2 0.8 0.6 0.2 26.3 0.1 3.3 0.1 2.7 0.6 1.3 0.8 3.2 1.8 1.9 0.0 0.4 0.1 0.5 0.0 0.2 0.0 16.7 6.4 8.2 1.0 6.0 1.3 335.2 10.4 2.8 6.0 16.3 12.7 1.8 7.2 14.7 0.0 4.2 2.0 0.7 731.7 0.0 21.3 3.5 5.0 5.2 22.3 17.3 0.4 1.7 16.1 9.4 2.9 12.8 28.7 8.9 4.6 41.4 37.7 1.4 5.0 1.4 46.1 4.1 5.9 3.1 0.2 0.0 2.6 7.2 0.0 0.9 1.3 2.1 0.5 0.6 58.7 585.4 0.7 0.2 244.9 97.5 11.1 3.9 6.4 0.0 2.7 3.1 4.3 3.9 9.2 1.0 0.7 5.5 2.2 33.2 618.9 CENPE "KIF10, PPP1R61" ENSG00000138778 "Centromere protein E" Q02224 4 103105349-103198445 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Developmental protein, Motor protein" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 10.0;lymphoid tissue: 9.2" "Cell type enhanced" "Detected in many" "Erythroid cells: 75.1;Extravillous trophoblasts: 28.4;Granulosa cells: 32.0;Spermatocytes: 75.3;Spermatogonia: 51.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "basophil: 2.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA011110, HPA042294" Enhanced Enhanced "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes Yes "Cluster 46: Basophils - DNA binding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Microtubules "Cytokinetic bridge, Mitotic spindle" "HPA011110: , HPA042294: AB_10797386" "unprognostic (1.62e-1)" "unprognostic (1.03e-1)" "unprognostic (5.64e-3)" "unprognostic (2.55e-2)" "unprognostic (1.65e-1)" "unprognostic (3.44e-2)" "unprognostic (2.40e-8)" "unprognostic (2.49e-3)" "unprognostic (1.59e-2)" "unprognostic (3.38e-1)" "unprognostic (4.88e-5)" "unprognostic (1.15e-2)" "unprognostic (0.00e+0)" "unprognostic (9.95e-3)" "unprognostic (2.49e-1)" "unprognostic (1.05e-1)" "unprognostic (2.37e-1)" 0.4 0.2 0.4 2.7 0.4 10.0 0.6 0.3 0.5 0.4 0.4 1.8 1.5 0.6 0.0 2.0 0.2 0.8 0.2 0.3 0.6 0.2 0.5 0.8 5.6 0.5 0.5 0.1 0.1 0.3 0.0 1.4 0.9 0.3 2.0 0.4 0.3 0.2 0.0 2.0 1.7 1.1 0.3 1.2 1.1 4.1 0.5 9.2 0.2 0.6 4.9 0.8 0.6 0.5 42.6 11.8 42.2 20.5 2.7 6.2 8.4 36.7 18.2 26.9 17.9 19.6 22.2 28.6 9.2 13.7 19.2 18.2 30.3 15.1 42.2 35.9 11.3 33.5 26.8 13.6 0.4 39.9 18.6 1.8 1.1 21.7 18.0 6.0 22.9 25.2 34.4 32.5 34.8 15.6 31.5 18.9 13.8 17.0 17.9 20.9 38.5 9.3 8.0 8.4 19.3 11.5 32.9 22.9 9.0 16.0 12.9 13.9 26.1 25.8 27.2 27.2 38.6 15.9 28.6 28.8 14.2 21.7 27.8 2.9 0.0 0.3 0.0 0.2 0.0 0.2 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.3 1.5 0.2 0.6 0.0 0.4 0.4 0.3 0.5 0.3 0.6 0.5 0.5 0.9 0.3 0.5 0.5 1.4 3.2 2.2 1.0 6.6 3.6 1.5 2.9 0.0 7.6 1.8 2.7 1.9 0.0 1.3 0.0 8.4 12.7 3.9 4.7 0.0 0.5 7.7 3.5 5.7 4.2 1.2 75.1 2.0 0.0 28.4 6.5 4.6 6.9 7.0 32.0 4.2 0.9 14.1 0.0 1.9 4.3 4.1 10.4 5.7 3.5 0.9 9.6 0.0 0.0 6.0 1.3 2.1 0.5 3.1 1.8 1.4 2.6 16.0 1.4 0.8 0.3 0.3 2.6 0.0 5.7 7.4 75.3 51.0 8.3 2.8 3.6 6.6 7.0 11.6 1.9 CENPF hcp-1 ENSG00000117724 "Centromere protein F" P49454 1 214603195-214664571 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, DNA synthesis, Mitosis, Myogenesis" "Developmental protein" "Cancer-related genes, Ciliopathy, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 28.8;lymphoid tissue: 33.0" "Cell type enhanced" "Detected in many" "Early spermatids: 84.4;Erythroid cells: 268.7;Extravillous trophoblasts: 78.8;Granulosa cells: 165.8;Spermatocytes: 107.5;Spermatogonia: 107.1" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" "HPA052382, HPA064308, CAB070134" Enhanced Supported Nucleoplasm Yes Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB070134: AB_2229328, HPA052382: AB_2681808, HPA064308: AB_2732711" "unprognostic (2.80e-1)" "unprognostic (2.16e-1)" "unprognostic (2.65e-1)" "unprognostic (5.30e-2)" "unprognostic (1.73e-1)" "unprognostic (2.40e-2)" "prognostic unfavorable (2.29e-5)" "unprognostic (1.13e-2)" "unprognostic (2.58e-3)" "unprognostic (1.11e-1)" "prognostic unfavorable (1.39e-4)" "unprognostic (1.58e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.92e-2)" "unprognostic (1.71e-1)" "unprognostic (1.89e-2)" "unprognostic (4.12e-1)" 0.8 1.1 0.1 4.4 0.1 28.8 1.8 0.0 0.3 1.3 0.5 5.8 6.1 1.8 0.1 8.6 0.6 0.7 0.4 0.3 0.0 0.4 0.9 0.9 8.5 0.3 0.5 0.7 0.3 0.2 0.1 3.1 0.3 0.5 5.7 1.0 1.4 0.1 0.2 6.2 4.3 2.5 0.2 2.4 2.6 10.5 0.5 33.0 0.4 0.6 10.0 1.4 2.6 0.3 123.7 68.4 144.3 75.8 5.4 7.2 56.3 74.6 30.3 43.9 42.8 54.6 74.1 116.3 43.1 41.7 39.8 74.7 89.9 49.2 74.1 102.6 56.6 96.0 111.4 78.6 0.8 137.0 50.5 2.7 3.8 63.3 72.3 12.7 46.9 52.6 88.4 68.0 79.4 47.0 81.5 54.3 127.9 36.8 30.0 85.7 203.7 38.6 43.2 30.3 67.4 91.2 100.7 66.2 38.9 76.2 79.1 51.9 61.7 78.9 92.2 66.2 155.9 51.6 60.7 108.7 34.4 96.7 71.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.3 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.3 0.3 0.0 0.3 0.5 0.3 0.2 0.5 0.3 3.0 0.0 3.1 0.0 11.5 9.3 2.8 11.2 3.4 4.7 10.0 6.7 1.9 1.5 9.9 0.0 0.0 53.3 10.8 19.1 0.0 2.0 84.4 30.1 19.3 12.4 0.0 268.7 1.3 0.4 78.8 19.0 32.1 25.2 1.3 165.8 8.9 2.6 32.2 1.7 0.8 20.1 14.2 16.6 6.6 19.8 1.2 16.2 1.8 1.0 0.7 1.4 5.2 0.0 0.1 0.5 1.1 3.0 25.9 2.3 2.1 0.1 16.7 3.1 0.0 8.3 23.9 107.5 107.1 44.6 5.5 5.1 23.3 11.7 41.3 3.7 CEP55 "C10orf3, CT111, FLJ10540" ENSG00000138180 "Centrosomal protein 55" Q53EZ4 10 93496612-93529092 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 27.4;testis: 21.7" "Cell type enhanced" "Detected in many" "Early spermatids: 29.4;Extravillous trophoblasts: 17.1;Granulosa cells: 19.8;Spermatocytes: 77.3;Spermatogonia: 17.3" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 8 "T-reg: 1.3" "Lineage enriched" "Detected in single" 14 "T-cells: 1.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" HPA023430 Approved Approved "Plasma membrane,Midbody,Centriolar satellite" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Centriolar satellite" Midbody "HPA023430: AB_10960212" "unprognostic (9.85e-2)" "unprognostic (1.12e-2)" "unprognostic (1.04e-1)" "unprognostic (1.29e-1)" "unprognostic (5.15e-2)" "unprognostic (4.26e-2)" "prognostic unfavorable (3.20e-9)" "prognostic unfavorable (1.45e-4)" "unprognostic (1.50e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (2.66e-5)" "unprognostic (3.99e-2)" "prognostic unfavorable (0.00e+0)" "prognostic favorable (3.15e-4)" "unprognostic (7.86e-2)" "unprognostic (1.49e-1)" "unprognostic (1.63e-1)" 1.3 0.6 0.0 7.6 0.0 5.0 1.4 0.0 0.2 1.7 0.0 7.0 6.7 1.4 0.1 7.3 0.4 1.4 0.3 0.0 0.1 0.3 0.6 1.3 14.7 0.1 0.3 0.2 0.2 0.2 0.3 3.5 0.2 0.3 8.8 0.0 1.2 0.3 0.1 4.5 6.3 5.2 0.0 2.4 4.6 21.7 0.4 27.4 0.5 0.2 15.5 3.1 2.3 0.1 208.5 81.5 53.0 67.7 5.8 12.0 29.6 112.4 78.2 103.5 106.4 87.2 108.6 55.4 48.2 72.8 69.6 115.4 64.8 54.8 123.4 167.2 33.7 21.0 49.2 29.9 0.6 36.3 46.3 2.8 3.8 110.6 133.5 30.7 97.1 89.9 19.3 101.8 118.5 48.3 96.3 54.8 20.9 64.2 58.8 41.3 86.9 30.3 47.1 25.5 21.7 30.7 86.3 26.3 64.9 40.1 68.9 36.4 61.4 65.3 90.6 90.5 186.7 45.1 66.1 66.8 51.0 134.8 59.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.3 0.2 0.0 0.4 0.1 0.2 0.0 1.3 0.0 2.7 3.6 0.9 1.9 0.0 0.0 1.8 2.0 0.4 2.8 0.2 0.0 0.0 7.7 0.9 3.3 0.0 0.6 29.4 1.7 2.0 1.5 0.0 2.5 0.5 0.2 17.1 2.3 8.2 3.6 0.0 19.8 2.2 0.3 12.9 0.0 0.3 4.5 4.1 7.0 5.1 8.2 0.3 5.1 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.3 0.0 0.4 14.8 1.1 0.4 0.0 0.2 0.0 0.0 0.5 4.5 77.3 17.3 16.1 1.3 1.5 4.3 1.6 7.9 1.7 CFD "ADN, DF, PFD" ENSG00000197766 "Complement factor D" P00746 19 859664-863641 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Complement alternate pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 1496.7;breast: 993.2" "Group enriched" "Detected in many" 6 "Fibroblasts: 9365.5;Leydig cells: 5032.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 297.6" "Lineage enriched" "Detected in all" 5 "granulocytes: 297.6" "Group enriched" "Detected in many" 5 "ASC diff: 197.4;THP-1: 342.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 732000000 4400000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 43: THP-1 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (3.00e-2)" "unprognostic (6.09e-2)" "unprognostic (2.44e-1)" "unprognostic (1.22e-3)" "unprognostic (6.92e-2)" "unprognostic (5.28e-2)" "unprognostic (8.11e-3)" "unprognostic (2.48e-1)" "unprognostic (1.46e-2)" "unprognostic (8.10e-2)" "prognostic favorable (1.77e-4)" "unprognostic (9.53e-2)" "prognostic unfavorable (7.09e-4)" "unprognostic (1.23e-1)" "unprognostic (4.55e-2)" "unprognostic (1.92e-2)" "unprognostic (9.75e-2)" 1496.7 33.3 1.5 9.6 1.6 10.7 993.2 1.2 2.4 597.4 3.7 324.8 23.5 58.4 2.4 212.8 258.0 9.6 854.2 1.7 2.3 18.1 8.7 363.3 2.1 3.3 2.3 74.3 41.4 1.7 9.0 14.5 3.6 277.8 10.9 0.6 247.3 6.3 197.0 488.6 248.4 4.0 2.6 28.6 263.8 51.8 2.9 3.6 332.3 26.9 0.8 848.3 729.8 5.8 3.9 5.2 0.6 2.2 197.4 26.2 9.5 0.8 0.0 0.0 0.0 0.8 0.4 0.2 5.7 0.0 0.5 3.0 1.8 0.5 0.0 5.7 14.5 0.5 12.3 3.8 3.6 2.5 4.9 8.7 0.2 0.1 0.0 0.8 0.0 4.5 11.9 0.9 0.0 2.6 0.6 49.2 1.0 4.5 16.1 1.3 0.5 5.2 0.3 1.2 1.8 1.8 5.5 1.9 0.5 0.6 7.5 342.2 0.4 0.2 5.1 2.9 0.6 7.8 4.7 0.4 0.2 20.8 0.2 297.6 41.2 127.8 8.4 55.5 13.2 5.7 4.2 10.2 14.5 1.4 9.7 9.7 112.0 1.3 57.3 1.8 4.7 37.8 1.5 1.6 1.2 2.4 1.7 2.3 3.3 2.3 3.6 2.6 2.9 5.8 857.8 9.6 23.3 0.0 19.2 785.5 49.0 10.1 17.1 2.9 107.3 120.1 55.5 21.5 30.9 18.4 2.1 36.6 40.0 33.1 11.7 7.7 27.1 23.1 593.3 114.8 4.2 8.2 0.2 0.0 32.9 9365.5 113.6 15.9 17.1 0.9 30.4 2.6 272.4 1.7 0.4 8.7 0.0 424.7 1145.2 89.6 5032.4 442.5 642.1 4.7 303.6 1.3 21.6 0.0 0.1 2.9 64.8 283.2 41.0 19.7 4.3 3.4 28.4 6.5 0.0 414.3 530.2 11.4 21.3 28.6 735.9 34.3 82.8 1.2 21.0 233.2 CHI3L1 "GP39, YK-40, YKL40" ENSG00000133048 "Chitinase 3 like 1" P36222 1 203178931-203186704 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Inflammatory response" Antimicrobial "Asthma, Cancer-related genes, Schizophrenia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 232.4;brain: 239.4;liver: 447.8" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 88.7;Ductal cells: 88.9;Hepatocytes: 61.8;Hofbauer cells: 317.5" "Cancer enriched" "Detected in all" 8 "glioma: 1313.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 495 "neutrophil: 470.4" "Lineage enriched" "Detected in single" 495 "granulocytes: 470.4" "Cell line enhanced" "Detected in some" "ASC diff: 322.9;ASC TERT1: 712.9;HSkMC: 637.0;THP-1: 1068.4;U-138 MG: 303.5;U-87 MG: 303.7" "Low region specificity" "Detected in all" "Region enriched" "Detected in some" 10 "olfactory bulb: 16.0" HPA077365 Approved "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 25100000 180000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 15: Liver - Metabolism" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus" Vesicles "HPA077365: " "unprognostic (2.11e-3)" "unprognostic (1.21e-1)" "unprognostic (1.29e-1)" "unprognostic (1.07e-1)" "unprognostic (6.01e-3)" "unprognostic (8.81e-2)" "unprognostic (2.09e-1)" "unprognostic (1.48e-1)" "unprognostic (4.46e-2)" "unprognostic (1.30e-1)" "unprognostic (7.98e-2)" "unprognostic (1.43e-1)" "unprognostic (1.20e-2)" "unprognostic (1.98e-2)" "unprognostic (3.43e-2)" "unprognostic (1.14e-2)" "unprognostic (9.39e-3)" 79.8 2.0 58.9 138.9 75.9 232.4 62.8 55.3 94.7 30.5 56.8 6.5 0.4 19.5 1.0 14.4 23.4 3.0 9.8 47.4 129.6 60.9 447.8 38.4 32.4 239.4 112.8 6.6 13.8 0.2 134.5 10.1 135.6 13.7 2.0 50.9 99.4 0.9 21.0 75.6 16.8 6.8 70.0 13.9 9.7 1.0 156.4 12.4 15.0 1.0 36.9 97.8 9.1 70.8 0.8 0.0 0.0 0.3 322.9 712.9 0.0 0.0 0.2 0.0 0.0 75.3 0.2 0.1 1.2 0.4 0.3 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 8.3 0.3 0.3 637.0 0.0 1.9 0.3 30.8 0.0 0.0 0.0 1.0 0.2 0.3 0.0 5.8 2.7 0.0 0.0 0.0 0.1 15.4 0.0 0.0 0.0 0.0 0.3 0.5 0.4 0.2 0.0 1068.4 0.0 303.5 1.6 0.0 0.4 2.3 41.9 0.3 303.7 1.2 0.2 0.0 0.4 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 470.4 0.0 0.9 0.0 0.0 1.3 58.9 75.9 55.3 94.7 47.4 129.6 239.4 112.8 135.6 70.0 156.4 70.8 0.7 6.4 42.8 20.5 0.1 4.2 47.1 88.7 0.0 0.1 29.8 21.5 1.0 2.8 17.3 27.6 0.0 1.3 0.6 0.0 0.0 88.9 0.0 4.8 2.2 2.1 0.0 0.4 1.1 0.0 1.1 18.6 0.0 7.2 0.0 0.0 0.0 61.8 317.5 0.0 0.1 0.0 6.1 0.8 0.4 0.0 0.9 23.7 14.2 0.0 1.0 45.1 0.0 0.0 0.1 2.0 0.0 0.0 1.4 4.2 0.0 0.2 3.4 2.8 0.0 1.0 2.3 0.0 0.0 1.5 1.1 0.8 0.9 0.0 0.0 2.2 CHRM1 ENSG00000168539 "Cholinergic receptor muscarinic 1" P11229 11 62908679-62921807 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 27.0;prostate: 29.6;salivary gland: 28.8" "Cell type enhanced" "Detected in some" "Astrocytes: 2.9;Breast myoepithelial cells: 3.6;Excitatory neurons: 8.7;Inhibitory neurons: 7.8;Intestinal goblet cells: 3.2;Melanocytes: 3.6;Oligodendrocyte precursor cells: 3.0;Prostatic glandular cells: 4.4" "Cancer enriched" "Detected in some" 16 "prostate cancer: 27.9" "Group enriched" "Detected in many" 178 "amygdala: 12.4;basal ganglia: 18.7;cerebral cortex: 27.0;hippocampal formation: 22.6;white matter: 8.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "MCF7: 3.7;OE19: 12.3" "Low region specificity" "Detected in many" HPA014101 Enhanced Supported NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 21: OE19 - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA014101: AB_1854210" "unprognostic (3.19e-2)" "unprognostic (2.14e-1)" "unprognostic (2.25e-1)" "unprognostic (1.31e-2)" "unprognostic (7.94e-2)" "unprognostic (2.29e-1)" "unprognostic (1.16e-2)" "unprognostic (2.89e-2)" "unprognostic (1.91e-1)" "unprognostic (2.76e-1)" "unprognostic (2.08e-1)" "unprognostic (8.57e-4)" "unprognostic (4.88e-1)" "unprognostic (6.43e-2)" "unprognostic (1.75e-1)" 0.0 3.3 12.4 0.3 18.7 0.0 2.7 0.0 27.0 0.0 0.0 0.8 0.4 0.1 0.0 0.3 0.2 0.1 0.1 22.6 0.0 0.2 0.0 2.5 0.0 0.0 0.0 0.0 0.6 0.3 0.2 0.2 0.0 29.6 0.7 0.1 28.8 0.0 0.0 2.8 0.7 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.1 0.0 12.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.9 0.4 0.1 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 18.7 0.0 27.0 22.6 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.1 0.0 0.0 2.9 0.0 0.1 0.2 0.0 0.0 0.0 1.8 3.6 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 8.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 7.8 3.2 0.0 0.0 0.3 0.0 0.0 0.0 3.6 1.0 0.0 0.0 0.0 3.0 1.0 0.0 0.1 0.0 0.0 4.4 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.1 CHRM3 ENSG00000133019 "Cholinergic receptor muscarinic 3" P20309 1 239386565-239915452 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.8;salivary gland: 17.5" "Group enriched" "Detected in many" 28 "Excitatory neurons: 802.9;Inhibitory neurons: 624.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "RPMI-8226: 17.2;SH-SY5Y: 53.5;U-266/70: 21.7;U-266/84: 16.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA024106, HPA048036" Approved Supported "Plasma membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "HPA024106: AB_1854211, HPA048036: AB_2680238" "unprognostic (1.63e-1)" "unprognostic (4.82e-2)" "unprognostic (1.05e-1)" "unprognostic (4.11e-3)" "unprognostic (3.48e-3)" "unprognostic (5.81e-2)" "unprognostic (2.30e-3)" "unprognostic (5.18e-2)" "unprognostic (1.71e-1)" "unprognostic (1.27e-1)" "unprognostic (6.29e-2)" "unprognostic (6.44e-2)" "unprognostic (5.34e-4)" "unprognostic (3.04e-2)" "unprognostic (2.67e-1)" "unprognostic (1.02e-1)" "unprognostic (4.88e-2)" 0.3 0.4 4.6 0.8 7.3 0.2 0.8 0.0 11.8 0.4 0.0 7.0 1.4 1.9 0.4 7.5 0.8 0.7 0.4 7.5 0.0 1.1 0.4 1.1 0.1 0.0 0.0 4.8 10.6 0.5 0.5 0.8 0.0 1.1 2.8 1.7 17.5 3.0 0.0 1.3 1.5 4.1 0.0 0.7 5.0 2.5 4.1 0.1 2.0 0.1 0.1 7.0 0.4 2.9 0.0 0.1 0.4 0.4 0.0 0.0 0.9 0.6 0.1 0.3 0.1 0.0 0.0 0.0 2.1 0.0 0.0 5.8 0.6 3.8 2.7 0.0 3.7 0.6 0.4 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.8 0.0 0.0 1.1 9.1 0.9 1.4 0.0 0.0 4.6 4.6 9.1 0.0 1.1 17.2 0.7 0.8 0.1 53.5 0.0 0.1 0.1 4.0 1.8 0.0 0.3 2.3 0.8 0.1 0.5 21.7 16.3 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 4.6 7.3 0.0 11.8 7.5 0.0 0.0 0.0 0.0 0.0 4.1 2.9 6.1 0.0 3.7 6.2 0.0 0.0 2.1 0.0 0.6 19.0 4.6 3.2 1.2 0.0 0.8 0.0 0.0 3.2 0.3 11.0 1.9 0.4 19.6 0.1 0.1 3.0 3.5 4.6 802.9 17.3 0.7 3.9 11.7 0.2 1.3 7.5 4.2 0.3 0.5 0.0 624.0 6.0 0.0 0.0 0.0 3.9 0.0 0.2 7.2 22.5 0.0 0.3 0.0 8.5 11.2 2.6 25.3 0.4 0.2 2.5 2.2 1.4 1.6 0.6 0.0 0.2 1.1 12.9 3.0 0.2 0.0 0.5 0.1 0.8 15.5 0.2 CHRNE ACHRE ENSG00000108556 "Cholinergic receptor nicotinic epsilon subunit" Q04844 17 4897771-4934438 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "heart muscle: 55.3;pituitary gland: 27.6" "Cell type enriched" "Detected in many" 5 "Late spermatids: 161.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "gdT-cell: 2.5" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 9 "HEL: 5.0;HMC-1: 11.5" "Not detected" "Not detected" "Region enriched" "Detected in single" 14 "basal ganglia: 6.3" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 3: HMC-1 - Innate immune response" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (2.00e-3)" "unprognostic (1.56e-1)" "unprognostic (3.94e-2)" "unprognostic (4.35e-3)" "unprognostic (6.55e-2)" "unprognostic (2.27e-3)" "unprognostic (7.80e-4)" "unprognostic (7.75e-2)" "unprognostic (3.24e-1)" "unprognostic (1.34e-1)" "unprognostic (3.69e-2)" "unprognostic (6.58e-2)" "unprognostic (8.42e-4)" "unprognostic (1.39e-3)" "unprognostic (1.26e-1)" "unprognostic (5.83e-2)" "unprognostic (5.70e-2)" 0.7 0.4 0.1 0.4 0.1 0.7 0.7 0.6 0.4 0.7 0.0 0.3 0.3 0.4 1.3 0.4 0.6 1.0 55.3 0.2 0.1 1.0 3.5 0.8 0.5 0.3 0.0 0.8 1.7 0.2 27.6 0.6 0.1 0.6 0.0 5.1 0.8 0.2 1.8 2.2 0.8 0.2 0.0 1.8 0.5 0.7 0.1 0.1 0.4 2.1 0.2 0.3 0.5 0.2 0.0 0.0 0.4 0.0 0.0 0.1 0.4 0.2 0.0 0.0 0.1 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 5.0 0.0 0.8 0.4 0.0 11.5 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.2 1.3 2.5 0.4 0.0 0.0 0.1 0.8 0.2 0.4 0.1 0.7 1.1 0.8 0.6 0.1 0.0 0.7 0.1 0.1 0.6 0.4 0.2 0.1 0.3 0.0 0.1 0.0 0.1 0.2 4.9 0.0 0.0 0.3 4.2 1.7 1.4 0.8 1.2 5.0 1.6 2.0 6.5 1.5 0.6 1.8 4.2 0.6 10.2 0.0 1.9 0.3 27.8 0.6 1.1 3.3 0.0 0.0 0.5 0.9 7.3 2.3 1.1 0.8 8.2 1.4 2.9 7.4 3.4 3.3 0.4 0.1 2.0 1.3 13.0 161.5 0.9 9.9 0.0 2.8 5.3 1.1 8.2 0.5 0.7 0.7 0.0 0.4 3.5 1.1 0.0 2.9 0.6 10.0 0.0 0.9 1.1 5.6 8.4 0.2 1.1 11.1 3.5 6.2 0.2 0.7 CIDEA CIDE-A ENSG00000176194 "Cell death inducing DFFA like effector a" O60543 18 12254361-12277595 "Disease related genes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 18 "adipose tissue: 221.3;breast: 108.0" "Cell type enriched" "Detected in some" 78 "Breast glandular cells: 330.6" "Cancer enhanced" "Detected in some" "breast cancer: 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 10 "hTEC/SVTERT24-B: 1.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 30: Mammary glandular cells - Lactation" "unprognostic (2.96e-2)" "unprognostic (2.43e-2)" "unprognostic (1.74e-1)" "unprognostic (1.49e-1)" "unprognostic (8.93e-3)" "unprognostic (3.20e-2)" "unprognostic (7.00e-2)" "unprognostic (3.72e-2)" "unprognostic (1.91e-3)" "unprognostic (3.17e-2)" "unprognostic (7.67e-3)" "unprognostic (1.96e-1)" 221.3 3.7 2.3 0.2 3.2 0.0 108.0 2.8 5.2 3.5 1.7 1.5 0.0 0.0 0.0 4.8 0.0 1.2 1.9 2.7 1.8 0.2 0.2 0.0 0.3 2.4 2.2 0.0 0.9 0.0 0.0 0.0 2.7 0.1 0.9 0.1 4.3 0.0 1.0 9.3 2.1 0.2 2.2 0.0 1.0 0.1 2.0 0.2 0.5 4.6 0.2 1.1 5.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 3.2 2.8 5.2 2.7 1.8 2.4 2.2 2.7 2.2 2.0 3.0 1.9 0.0 0.0 0.7 0.5 0.1 0.1 0.3 0.0 0.2 330.6 3.8 0.6 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.3 1.0 0.0 0.2 0.3 0.0 0.0 3.3 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 4.2 0.6 0.6 1.8 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.6 0.4 0.3 0.7 1.0 0.0 0.3 0.5 0.0 0.8 CKAP2L "FLJ40629, radmis" ENSG00000169607 "Cytoskeleton associated protein 2 like" Q8IYA6 2 112736349-112764664 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 13.1;lymphoid tissue: 12.1;testis: 4.5" "Cell type enhanced" "Detected in many" "Erythroid cells: 25.2;Granulosa cells: 12.5;Spermatocytes: 33.0;Spermatogonia: 35.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA039407, HPA040057, HPA070737" Uncertain Supported "Microtubules,Mitotic spindle,Cytosol" Yes Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Microtubules, Mitotic spindle" Cytosol "HPA039407: AB_10794091, HPA040057: AB_10794871, HPA070737: AB_2686303" "unprognostic (2.29e-1)" "unprognostic (1.54e-1)" "unprognostic (4.69e-3)" "unprognostic (1.42e-3)" "unprognostic (1.69e-1)" "unprognostic (5.59e-2)" "unprognostic (5.75e-5)" "prognostic unfavorable (7.63e-4)" "unprognostic (2.49e-3)" "unprognostic (1.91e-1)" "unprognostic (9.57e-6)" "unprognostic (2.42e-1)" "unprognostic (0.00e+0)" "unprognostic (7.37e-2)" "unprognostic (1.24e-1)" "unprognostic (1.30e-1)" "unprognostic (4.49e-2)" 0.4 0.1 0.2 2.6 0.2 13.1 0.4 0.4 0.3 0.4 0.0 1.6 1.5 0.3 0.1 2.3 0.1 0.3 0.0 0.2 0.1 0.1 0.3 0.3 5.0 0.0 0.1 0.0 0.0 0.0 0.0 1.8 0.0 0.1 2.2 0.2 0.3 0.0 0.0 1.5 1.1 1.1 0.0 0.9 1.0 4.5 0.2 12.1 0.2 0.0 5.2 0.8 0.6 0.2 47.9 9.6 35.4 16.2 2.0 3.3 7.2 38.5 32.2 37.9 36.1 8.7 13.3 32.0 15.5 15.1 48.3 18.0 20.4 19.6 64.1 44.8 8.9 53.6 12.7 7.7 0.1 25.2 30.9 0.9 1.9 47.4 27.2 10.1 17.5 22.8 14.3 44.9 31.2 6.9 31.0 10.6 15.4 20.0 29.5 22.3 37.0 8.4 6.9 18.7 19.7 12.7 15.2 12.8 13.3 13.2 12.4 11.8 12.9 42.7 33.7 34.5 28.5 9.9 20.1 26.6 18.5 18.1 69.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.2 0.2 0.4 0.3 0.2 0.1 0.0 0.1 0.0 0.0 0.2 0.2 0.1 3.2 0.6 0.0 1.2 3.3 2.1 2.7 0.6 0.0 0.5 0.8 0.5 1.5 0.4 0.0 0.0 11.1 1.3 1.3 0.0 0.4 2.4 1.1 1.6 1.1 0.0 25.2 0.3 0.4 10.6 2.0 1.5 2.1 0.0 12.5 2.9 0.1 6.6 0.0 0.2 3.1 2.0 1.9 1.4 2.1 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.1 0.0 5.6 1.1 0.1 0.1 0.4 0.0 0.0 0.4 2.8 33.0 35.7 9.5 1.7 1.0 2.5 0.7 3.8 1.1 CLCNKA hClC-Ka ENSG00000186510 "Chloride voltage-gated channel Ka" P51800 1 16018875-16034050 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Ion transport, Transport" "Chloride channel, Ion channel, Voltage-gated channel" "Bartter syndrome, Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "kidney: 344.0" "Cell type enriched" "Detected in some" 4 "Late spermatids: 271.5" "Group enriched" "Detected in some" 7 "renal cancer: 4.4;thyroid cancer: 1.6" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "U-266/70: 7.4" HPA057717 Approved NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 31: Spermatids - Spermatogenesis" "HPA057717: AB_2683509" "unprognostic (2.35e-2)" "unprognostic (1.24e-1)" "unprognostic (1.37e-2)" "unprognostic (4.02e-1)" "unprognostic (2.76e-3)" "unprognostic (8.20e-2)" "unprognostic (6.16e-2)" "unprognostic (1.18e-2)" "unprognostic (6.92e-3)" "unprognostic (3.49e-2)" "unprognostic (1.76e-2)" "unprognostic (1.41e-1)" "unprognostic (8.13e-3)" "unprognostic (1.36e-1)" "unprognostic (9.13e-2)" "unprognostic (4.37e-3)" "unprognostic (1.28e-1)" 0.7 2.9 0.4 0.0 0.4 0.0 0.9 2.2 0.4 0.6 4.9 0.4 0.0 0.6 0.5 0.0 0.5 0.1 0.6 0.7 0.4 344.0 0.2 0.3 0.0 0.4 0.5 0.9 3.5 48.9 18.2 0.0 0.7 0.8 0.0 2.3 6.9 0.2 0.5 0.7 0.1 0.2 0.3 0.1 3.9 4.5 0.4 0.0 21.6 0.3 0.0 0.2 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.2 1.6 0.0 0.0 0.0 0.0 0.0 1.7 0.1 0.2 0.1 0.3 0.0 0.0 0.0 0.0 0.0 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 2.2 0.4 0.7 0.4 0.4 0.5 0.7 0.3 0.4 0.4 0.0 3.2 0.5 0.3 0.0 0.1 0.1 0.0 0.0 3.9 0.4 0.1 3.8 0.0 0.7 25.8 0.0 0.4 0.0 0.1 25.4 0.3 40.2 0.1 0.0 0.1 1.2 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 4.5 0.0 0.0 0.1 13.5 0.2 0.1 67.1 0.0 0.0 271.5 0.3 0.0 1.8 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.3 0.0 0.7 0.0 0.0 0.1 1.9 1.2 0.0 0.0 0.7 0.1 0.0 0.3 0.2 CLDN10 "CPETRL3, OSP-L" ENSG00000134873 "Claudin 10" P78369 13 95433604-95579759 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 135.2;pancreas: 216.5;salivary gland: 91.5" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 182.4;Cholangiocytes: 328.8;Club cells: 251.6;Ductal cells: 394.1;Glandular and luminal cells: 220.2;Proximal tubular cells: 285.9" "Cancer enhanced" "Detected in many" "pancreatic cancer: 19.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "eosinophil: 1.3;neutrophil: 4.1" "Lineage enriched" "Detected in single" 11 "granulocytes: 4.1" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 14.9;NTERA-2: 12.7;RPTEC TERT1: 29.0;SuSa: 73.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012969, HPA042348" Enhanced NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "CAB012969: AB_2533386, HPA042348: AB_2677955" "unprognostic (6.45e-2)" "unprognostic (5.72e-2)" "unprognostic (3.35e-1)" "unprognostic (4.60e-2)" "unprognostic (4.73e-2)" "unprognostic (2.46e-3)" "unprognostic (6.91e-2)" "unprognostic (2.60e-1)" "unprognostic (1.88e-1)" "unprognostic (1.91e-3)" "unprognostic (2.59e-3)" "unprognostic (7.93e-2)" "prognostic favorable (7.46e-5)" "unprognostic (1.11e-2)" "unprognostic (9.94e-2)" "prognostic favorable (2.13e-4)" "unprognostic (4.75e-3)" 1.0 0.1 33.0 0.0 31.3 3.2 3.1 28.6 45.8 30.4 24.1 0.3 1.1 9.3 20.8 7.9 19.2 25.5 0.5 32.6 30.5 135.2 3.7 2.1 0.0 27.9 30.2 0.9 216.5 0.4 3.1 0.8 27.2 1.3 0.4 2.7 91.5 0.4 0.1 16.8 0.2 0.4 27.4 0.7 0.9 1.5 30.1 0.5 0.2 0.7 27.4 0.5 0.4 29.8 0.0 0.0 0.9 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 2.7 0.0 4.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.3 1.9 0.0 0.0 2.9 0.0 0.1 0.0 0.5 14.9 0.0 0.0 0.0 0.0 0.1 0.0 0.2 12.7 0.2 0.0 0.0 0.1 0.0 29.0 0.0 0.2 0.1 0.0 0.0 0.0 73.3 0.7 1.8 0.6 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.1 0.0 0.0 33.0 31.3 28.6 45.8 32.6 30.5 27.9 30.2 27.2 27.4 30.1 29.8 0.6 0.0 0.0 93.4 1.0 0.3 5.5 182.4 0.0 0.3 22.6 5.0 0.8 328.8 251.6 99.3 0.0 15.0 0.4 0.0 135.0 394.1 3.4 83.2 28.5 4.2 0.0 0.0 0.6 82.5 7.9 1.4 0.0 220.2 0.0 0.1 1.1 0.4 1.9 0.0 1.6 0.0 77.3 0.3 0.3 2.5 0.0 2.8 69.4 4.7 1.6 78.7 0.0 33.7 0.4 103.1 0.0 0.4 0.1 22.1 0.0 285.9 43.3 3.8 6.6 0.2 16.8 12.2 19.9 1.5 0.6 23.1 2.2 0.5 0.0 5.0 CLEC2A "INPE5792, KACL, PILAR, UNQ5792" ENSG00000188393 "C-type lectin domain family 2 member A" Q6UVW9 12 9898673-9932370 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "skin 1: 57.6" "Group enriched" "Detected in some" 11 "Basal keratinocytes: 18.7;Suprabasal keratinocytes: 37.1" "Cancer enhanced" "Detected in some" "cervical cancer: 1.1" "Region enhanced" "Detected in single" "cerebellum: 2.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "fHDF/TERT166: 22.0;U-937: 54.6" "HPA048530, HPA072407" Approved Uncertain "Plasma membrane" NA NA "Cluster 61: Skin - Cornification" "Cluster 32: U-937 - Innate immune response" "Cluster 28: Keratinocytes - Keratinization" "Plasma membrane" "HPA048530: AB_2680429, HPA072407: AB_2686518" "unprognostic (3.10e-1)" "unprognostic (5.29e-2)" "unprognostic (2.23e-1)" 0.0 0.0 0.1 0.0 0.2 0.0 3.5 2.1 0.3 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.2 57.6 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.1 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 54.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 2.1 0.3 0.2 0.3 0.5 0.3 0.5 0.1 0.3 0.6 0.0 0.0 0.0 0.0 0.0 18.7 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.0 37.1 0.0 0.1 0.0 0.0 0.1 CLPSL2 "C6orf126, dJ510O8.5, UNQ3045" ENSG00000196748 "Colipase like 2" Q6UWE3 6 35776594-35779552 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 102 "epididymis: 532.1" "Group enriched" "Detected in some" 4 "Breast glandular cells: 3.4;Breast myoepithelial cells: 2.2;Enteroendocrine cells: 1.8;Exocrine glandular cells: 4.0;Pancreatic endocrine cells: 2.1;Spermatogonia: 2.2" "Cancer enhanced" "Detected in some" "breast cancer: 2.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "T-47d: 6.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA051655 Approved "Secreted in male reproductive system" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 6: T47d - Mammary gland" "Cluster 1: Pancreatic cells - Digestion" "HPA051655: " "unprognostic (2.38e-1)" "unprognostic (3.65e-1)" "unprognostic (6.39e-3)" "unprognostic (9.38e-2)" "unprognostic (4.03e-2)" "unprognostic (2.47e-1)" "unprognostic (4.85e-3)" "unprognostic (8.69e-2)" "unprognostic (3.17e-2)" "unprognostic (3.95e-2)" "unprognostic (1.49e-1)" "unprognostic (1.13e-1)" "unprognostic (2.37e-1)" 0.0 0.0 0.3 0.0 0.4 0.1 0.4 0.2 0.8 0.0 0.2 0.0 0.0 0.0 532.1 0.0 0.0 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.2 0.4 0.0 5.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 1.7 0.7 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.3 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.4 0.2 0.2 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.7 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.3 0.0 0.1 6.3 0.7 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.3 0.4 0.2 0.8 0.6 0.4 0.2 0.4 0.2 0.2 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 2.2 0.1 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.1 0.3 0.1 0.0 0.0 1.8 0.0 0.2 4.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 CNDP1 "CN1, CPGL2, HsT2308, MGC10825" ENSG00000150656 "Carnosine dipeptidase 1" Q96KN2 18 74534500-74587212 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 85.6" "Cell type enriched" "Detected in some" 10 "Oligodendrocytes: 361.7" "Cancer enhanced" "Detected in some" "glioma: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 38 "U-266/84: 15.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA008933, HPA073283" Enhanced "Secreted to blood" NA NA 2100000000 "Cluster 70: Brain - Nervous system development" "Cluster 16: U-266 - Nucleosome" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA008933: AB_1847033, HPA073283: " "unprognostic (7.43e-3)" "unprognostic (6.00e-2)" "unprognostic (8.55e-3)" "unprognostic (3.93e-1)" "unprognostic (1.32e-1)" "unprognostic (2.17e-2)" "unprognostic (8.04e-3)" "unprognostic (1.12e-2)" "unprognostic (2.81e-1)" "unprognostic (1.16e-1)" "unprognostic (1.16e-1)" "unprognostic (1.66e-1)" "unprognostic (6.90e-3)" "unprognostic (1.14e-1)" "unprognostic (3.30e-2)" "unprognostic (1.33e-1)" "unprognostic (1.28e-1)" 0.0 0.0 27.4 0.0 74.2 0.1 0.0 80.4 39.0 0.0 6.0 0.0 1.3 0.0 0.7 0.0 0.0 0.1 0.0 30.5 51.3 0.5 12.9 0.0 0.0 85.6 76.9 0.0 0.0 0.0 0.2 0.0 74.3 0.1 0.0 0.1 0.0 0.1 1.4 0.1 0.2 0.0 39.7 0.0 0.0 0.3 74.9 0.0 0.2 0.0 0.0 0.0 0.0 80.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 15.4 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 27.4 74.2 80.4 39.0 30.5 51.3 85.6 76.9 74.3 39.7 74.9 80.7 0.2 0.0 0.0 0.3 0.2 0.1 0.4 0.2 0.0 0.6 0.5 0.3 0.7 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 8.6 0.5 0.2 0.2 0.0 2.7 1.2 0.2 0.0 0.3 0.0 1.5 0.0 0.2 0.7 35.1 0.1 0.0 1.5 0.7 0.0 1.2 1.1 3.1 0.0 0.2 0.0 1.0 0.0 0.5 0.0 3.0 361.7 0.2 0.1 0.0 0.0 0.4 0.4 24.5 0.0 1.0 0.0 0.6 0.2 1.0 0.4 0.0 0.3 0.0 0.4 0.0 0.5 0.2 CNN1 "Sm-Calp, SMCC" ENSG00000130176 "Calponin 1" P51911 19 11538767-11550323 "Cancer-related genes, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 1872.4;intestine: 2657.3;smooth muscle: 2207.8" "Group enriched" "Detected in many" 5 "Breast myoepithelial cells: 191.0;Early spermatids: 335.0;Late spermatids: 554.6;Peritubular cells: 221.2;Smooth muscle cells: 180.9" "Cancer enhanced" "Detected in all" "prostate cancer: 142.1;stomach cancer: 103.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 91.5;BJ hTERT+: 34.9;BJ hTERT+ SV40 Large T+: 48.0;BJ hTERT+ SV40 Large T+ RasG12V: 64.6;HBF TERT88: 71.2;K-562: 35.8;SuSa: 72.5;U-2 OS: 34.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB000007, HPA014263" Enhanced Approved "Actin filaments" No No "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 34: Spermatids - Unknown function" "Actin filaments" "CAB000007: AB_2082148, HPA014263: AB_1847039" "unprognostic (4.98e-3)" "unprognostic (1.01e-1)" "unprognostic (3.04e-3)" "unprognostic (1.95e-1)" "unprognostic (2.47e-1)" "unprognostic (4.20e-1)" "unprognostic (5.10e-3)" "unprognostic (1.76e-1)" "unprognostic (1.35e-1)" "unprognostic (7.06e-2)" "unprognostic (2.19e-1)" "unprognostic (2.01e-1)" "prognostic unfavorable (5.43e-6)" "unprognostic (1.70e-2)" "unprognostic (1.07e-1)" "unprognostic (2.78e-3)" "unprognostic (6.11e-3)" 115.6 58.4 6.4 160.6 8.3 0.0 89.7 5.7 14.2 366.9 7.5 2657.3 136.3 1872.4 177.0 677.5 655.6 234.3 274.1 6.8 8.5 42.9 10.6 98.7 7.3 6.1 6.8 114.1 24.2 3.0 9.0 28.4 6.3 676.0 326.4 0.7 61.6 1585.7 21.8 57.8 431.3 2207.8 6.1 22.1 673.7 91.4 7.5 2.6 38.5 11.7 0.9 1386.6 305.7 6.3 0.1 1.3 5.9 1.0 0.6 0.2 3.2 91.5 34.9 48.0 64.6 27.9 0.0 0.4 2.7 26.1 4.4 0.3 0.0 0.0 71.2 0.0 0.2 0.1 0.1 2.3 2.5 0.0 0.4 3.0 0.1 28.7 0.1 1.6 0.0 0.0 35.8 0.0 0.0 0.0 0.3 3.8 2.9 0.0 0.7 0.2 0.6 3.8 0.0 0.0 0.1 1.3 0.1 0.2 0.2 72.5 0.1 0.1 0.4 0.4 34.6 1.2 1.2 0.1 0.4 0.1 3.2 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 6.4 8.3 5.7 14.2 6.8 8.5 6.1 6.8 6.3 6.1 7.5 6.3 2.4 0.0 0.0 0.0 0.2 4.8 4.1 1.6 0.6 0.0 4.2 191.0 51.4 0.0 0.3 1.8 0.0 0.8 0.7 0.0 0.0 14.5 335.0 3.1 20.7 2.4 0.0 0.0 0.5 0.4 1.0 21.5 0.5 0.7 0.0 0.5 6.8 0.0 2.3 0.0 0.3 0.0 0.0 0.0 9.4 554.6 8.4 0.9 3.6 2.8 0.6 0.5 0.0 0.0 0.1 0.9 0.0 221.2 0.0 4.0 0.0 0.4 0.4 0.0 39.5 1.1 180.9 8.3 19.5 0.4 7.1 0.7 1.1 0.7 0.0 1.1 CNOT2 "CDC36, NOT2, NOT2H" ENSG00000111596 "CCR4-NOT transcription complex subunit 2" Q9NZN8 12 70243002-70354993 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "RNA-mediated gene silencing, Transcription, Transcription regulation, Translation regulation" "Developmental protein, Repressor" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067711 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 44: Endometrium - Transcription" Nucleoplasm Cytosol "HPA067711: AB_2685893" "unprognostic (5.00e-2)" "unprognostic (2.12e-1)" "unprognostic (6.95e-2)" "unprognostic (3.60e-2)" "unprognostic (3.48e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (2.21e-4)" "unprognostic (7.36e-2)" "prognostic unfavorable (6.86e-4)" "unprognostic (1.32e-1)" "unprognostic (9.70e-2)" "unprognostic (2.99e-2)" "prognostic unfavorable (8.63e-5)" "unprognostic (1.28e-1)" "unprognostic (5.58e-2)" "unprognostic (5.97e-2)" "unprognostic (6.23e-2)" 29.8 25.6 24.2 31.2 33.3 78.5 35.0 65.9 28.1 29.2 24.9 31.6 30.2 34.3 34.5 24.4 29.0 27.3 24.0 25.2 28.8 28.7 34.9 29.5 40.4 33.7 32.1 35.1 24.1 32.5 23.4 32.1 30.0 27.8 34.5 46.2 26.0 27.0 33.4 50.3 30.9 30.5 28.6 35.8 25.7 26.2 32.3 50.1 30.7 33.8 42.7 32.8 27.9 43.5 46.2 44.5 70.7 45.3 38.5 42.8 60.1 49.2 59.5 53.8 46.1 55.8 42.1 100.2 45.1 57.4 33.8 43.9 50.2 49.1 59.7 47.1 50.2 66.4 38.8 55.7 40.7 84.3 54.6 50.1 52.4 50.5 59.1 78.7 59.0 61.5 61.9 55.4 47.2 52.4 95.7 61.0 61.0 46.1 46.4 75.1 59.9 61.1 50.7 93.2 50.6 55.7 59.1 46.4 45.6 60.5 59.1 68.4 44.7 50.2 33.6 45.8 40.7 50.3 59.5 77.3 52.5 42.3 41.9 92.8 49.2 57.6 50.1 69.4 56.6 54.0 54.7 58.9 60.3 51.5 62.6 67.6 30.3 62.6 58.5 44.4 55.8 56.3 24.2 33.3 65.9 28.1 25.2 28.8 33.7 32.1 30.0 28.6 32.3 43.5 71.1 41.7 43.2 76.7 79.8 51.1 37.7 45.4 47.3 64.4 40.9 38.0 30.1 58.6 45.6 36.8 56.3 45.3 144.3 50.2 33.2 49.5 44.5 47.8 55.8 55.4 58.0 49.2 110.9 44.7 47.4 57.4 41.3 62.2 76.5 60.1 46.4 34.6 40.3 52.2 115.8 39.0 44.7 55.1 46.7 12.6 45.7 62.7 32.0 86.2 46.3 54.3 56.7 123.6 204.0 45.8 44.4 46.6 77.9 45.4 45.2 30.3 44.7 54.8 39.5 72.3 64.5 53.8 44.7 46.7 64.1 35.4 94.2 50.4 39.2 48.9 COL1A1 OI4 ENSG00000108821 "Collagen type I alpha 1 chain" P02452 17 50184101-50201632 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Dwarfism, Ehlers-Danlos syndrome, FDA approved drug targets, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 1331.8;gallbladder: 1211.3" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 2044.3;Fibroblasts: 1944.4;Leydig cells: 556.0;Smooth muscle cells: 1024.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 1689.5;BJ: 3428.1;fHDF/TERT166: 5206.1;HSkMC: 2490.3;U-138 MG: 2687.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 115.9" "HPA011795, HPA012111" Approved Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" NA NA 80000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" Vesicles "HPA011795: AB_1847088, HPA012111: " "unprognostic (1.61e-1)" "unprognostic (3.60e-3)" "unprognostic (8.29e-2)" "unprognostic (5.52e-2)" "unprognostic (7.74e-2)" "unprognostic (2.22e-1)" "unprognostic (6.01e-2)" "prognostic unfavorable (4.43e-4)" "unprognostic (1.23e-2)" "unprognostic (2.55e-2)" "unprognostic (8.53e-2)" "unprognostic (9.90e-2)" "prognostic unfavorable (7.19e-12)" "unprognostic (2.74e-2)" "unprognostic (4.73e-2)" "unprognostic (7.26e-2)" "unprognostic (3.87e-3)" 312.1 39.9 1.8 272.8 5.3 4.5 184.9 1.3 15.9 1331.8 12.0 223.2 37.7 531.4 23.4 110.2 234.1 1211.3 126.6 1.5 1.9 34.7 29.7 139.0 78.1 3.2 1.4 377.3 39.8 14.1 80.5 503.5 2.0 137.5 46.5 0.4 51.3 98.6 21.2 362.0 86.6 801.2 2.2 46.9 109.9 38.2 17.3 14.4 50.8 13.0 21.1 616.3 342.2 6.7 6.0 5.0 16.4 3.2 702.9 1689.5 29.2 3428.1 915.8 826.6 517.6 64.2 14.6 0.6 7.8 5206.1 5.7 9.1 8.3 3.4 150.1 5.2 6.1 0.4 92.2 4.2 1309.3 1.2 0.8 2490.3 45.7 1016.2 4.6 126.9 0.5 4.8 2.2 0.4 425.4 8.5 1.4 1.0 17.0 10.7 10.5 6.1 2.1 2.7 3.9 0.2 2.0 8.8 5.6 5.0 0.2 245.4 39.8 0.6 1.5 2687.4 562.6 405.0 16.2 2.8 5.9 0.7 200.1 1.3 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 5.3 1.3 15.9 1.5 1.9 3.2 1.4 2.0 2.2 17.3 6.7 66.9 9.6 13.8 0.0 2.1 188.0 12.4 31.6 10.8 0.2 9.1 10.0 12.5 5.7 13.2 7.3 0.0 45.7 1.7 1.4 0.0 13.3 1.9 64.6 2044.3 33.4 3.0 0.0 0.1 4.2 45.5 1944.4 17.9 49.2 2.5 8.1 378.0 3.4 67.6 0.0 0.3 5.4 6.1 0.3 318.1 18.2 556.0 13.1 188.5 12.2 0.0 2.5 0.0 0.0 0.0 23.8 0.3 268.1 1.3 10.7 0.1 0.7 9.8 0.2 78.9 74.8 1024.9 4.0 2.6 4.3 163.5 111.8 29.4 57.3 2.9 9.1 COL3A1 EDS4A ENSG00000168542 "Collagen type III alpha 1 chain" P02461 2 188974373-189012746 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Aortic aneurysm, Disease variant, Ehlers-Danlos syndrome, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 2369.0;gallbladder: 2092.8;placenta: 1981.7;smooth muscle: 2140.7" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 2812.0;Fibroblasts: 1764.2;Smooth muscle cells: 643.0;Theca cells: 466.8" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in all" 4 "cerebral cortex: 15.0;thalamus: 10.9;white matter: 4.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 1362.4;ASC diff: 2465.0;ASC TERT1: 4252.6;fHDF/TERT166: 1815.7;HHSteC: 1690.0;HSkMC: 3189.5" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 61.1" "HPA007583, CAB016766, CAB059993" Approved Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 32000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "CAB016766: , CAB059993: AB_2314211, HPA007583: AB_1078548" "unprognostic (1.12e-1)" "unprognostic (2.03e-2)" "unprognostic (1.02e-1)" "unprognostic (6.01e-2)" "unprognostic (2.78e-1)" "unprognostic (2.04e-1)" "unprognostic (6.94e-2)" "unprognostic (6.77e-3)" "unprognostic (3.57e-3)" "unprognostic (2.60e-2)" "unprognostic (1.89e-2)" "unprognostic (1.99e-1)" "prognostic unfavorable (3.59e-10)" "unprognostic (1.70e-3)" "unprognostic (3.76e-2)" "unprognostic (7.61e-2)" "unprognostic (6.17e-3)" 763.6 48.9 1.1 575.5 2.3 1.1 340.0 1.4 15.0 2369.0 11.5 275.9 84.5 768.9 60.9 298.5 177.6 2092.8 234.6 1.3 1.4 42.9 97.4 187.0 119.0 1.8 2.0 146.9 45.2 37.0 13.6 1981.7 2.2 147.5 334.7 0.0 65.6 276.9 67.1 329.8 152.5 2140.7 1.9 134.7 156.9 63.5 10.9 40.9 71.8 71.8 73.1 1097.6 273.8 4.6 0.0 0.2 1362.4 53.0 2465.0 4252.6 0.9 558.6 495.3 239.4 212.8 8.1 0.0 0.6 0.3 1815.7 0.1 0.8 1.1 1.0 26.4 0.0 0.9 0.7 228.9 0.2 1690.0 2.0 0.6 3189.5 0.0 291.5 46.9 1.0 12.5 0.0 0.4 0.0 146.4 0.0 0.2 1.4 2.6 0.1 1.7 0.3 38.5 0.5 0.0 7.2 1.3 21.1 14.5 0.4 0.0 954.8 0.1 0.0 0.7 2.3 28.0 117.3 0.5 2.8 1.3 0.4 0.5 1.1 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 2.3 1.4 15.0 1.3 1.4 1.8 2.0 2.2 1.9 10.9 4.6 111.8 3.2 13.7 0.0 0.6 171.6 0.4 1.9 3.4 0.0 7.7 9.9 11.1 0.0 1.3 0.0 0.0 57.9 1.6 0.0 0.0 2.4 29.0 75.4 2812.0 68.4 6.0 0.0 0.0 0.0 58.1 1764.2 4.1 60.7 6.3 9.7 235.2 0.9 91.1 0.0 0.2 0.0 0.0 0.6 275.3 20.8 323.1 17.5 172.5 20.6 0.0 0.0 0.0 0.0 0.0 3.7 0.0 235.9 1.5 0.6 0.0 0.2 1.6 0.0 453.6 224.3 643.0 0.9 1.5 2.2 155.7 126.3 29.1 466.8 0.0 0.4 COL5A1 ENSG00000130635 "Collagen type V alpha 1 chain" P20908 9 134641803-134844843 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Heparin-binding "Cancer-related genes, Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 146.6" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 141.1;Fibroblasts: 134.9;Leydig cells: 61.2;Sertoli cells: 52.6;Skeletal myocytes: 78.3;Smooth muscle cells: 57.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 446.6;fHDF/TERT166: 414.6;HeLa: 297.0;HHSteC: 265.8;SiHa: 290.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA030769 Approved Approved Vesicles "Secreted to extracellular matrix" No No 15000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Vesicles "HPA030769: AB_2673603" "unprognostic (7.77e-2)" "unprognostic (4.55e-3)" "unprognostic (2.22e-2)" "unprognostic (2.33e-1)" "prognostic unfavorable (9.56e-4)" "unprognostic (8.07e-2)" "unprognostic (8.09e-2)" "unprognostic (2.38e-3)" "unprognostic (1.54e-2)" "unprognostic (5.03e-3)" "unprognostic (5.05e-2)" "unprognostic (1.40e-1)" "prognostic unfavorable (2.07e-12)" "unprognostic (2.02e-2)" "unprognostic (4.73e-2)" "unprognostic (1.65e-2)" "unprognostic (2.50e-3)" 39.3 12.0 1.3 39.1 1.5 1.0 20.0 1.9 2.7 146.6 3.4 72.0 13.5 118.2 11.1 23.2 59.6 77.6 32.8 1.2 1.9 11.5 7.6 35.7 5.5 4.0 2.5 51.9 7.0 6.8 6.6 95.8 1.3 43.8 16.3 3.1 9.3 28.9 10.2 24.6 22.0 89.6 1.8 17.6 31.4 6.2 4.6 2.3 10.1 7.3 2.9 51.6 63.4 1.4 0.6 16.7 13.0 20.7 192.2 202.4 7.9 446.6 89.0 73.6 78.6 0.2 0.3 0.0 95.3 414.6 39.8 5.6 0.0 0.1 21.3 0.1 1.0 0.3 297.0 0.1 265.8 0.2 2.7 200.0 0.2 71.1 5.6 0.0 89.2 0.1 0.1 1.2 39.5 4.1 0.3 0.9 7.6 0.0 8.5 15.7 50.3 1.8 0.1 0.1 5.3 2.5 290.0 1.8 0.2 173.7 0.6 0.2 152.6 154.4 61.9 190.4 93.7 0.3 0.2 0.4 121.6 0.1 26.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.5 1.9 2.7 1.2 1.9 4.0 2.5 1.3 1.8 4.6 1.4 7.9 0.0 1.8 0.7 0.3 14.5 3.5 0.8 3.4 8.5 0.8 2.7 9.0 0.0 0.0 1.8 2.1 6.4 0.3 0.0 1.9 2.2 5.5 4.2 141.1 8.8 0.0 0.0 6.6 0.0 12.3 134.9 1.5 4.8 0.0 1.2 21.8 0.0 8.9 0.0 1.2 0.0 0.0 0.3 15.3 15.6 61.2 1.5 7.2 12.2 0.0 6.4 0.0 5.5 0.3 1.3 0.0 38.7 0.3 1.0 0.0 0.3 0.0 1.2 52.6 78.3 57.5 0.5 0.8 0.6 7.7 10.4 2.6 11.7 0.0 0.4 CRACR2A "EFCAB4B, MGC4266" ENSG00000130038 "Calcium release activated channel regulator 2A" Q9BSW2 12 3606633-3764819 "Predicted intracellular proteins" "Adaptive immunity, Calcium transport, Immunity, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 17.0;intestine: 13.5;salivary gland: 38.6" "Cell type enhanced" "Detected in many" "dendritic cells: 14.9;Intestinal goblet cells: 46.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "basophil: 16.9" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 29.4" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA038686 Enhanced NA NA "Cluster 34: Basophils - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" "HPA038686: AB_10671748" "unprognostic (6.78e-2)" "unprognostic (3.82e-2)" "unprognostic (3.96e-2)" "unprognostic (9.15e-2)" "unprognostic (1.40e-3)" "unprognostic (1.03e-1)" "unprognostic (1.24e-1)" "unprognostic (1.71e-2)" "unprognostic (2.17e-2)" "unprognostic (5.47e-2)" "unprognostic (5.11e-2)" "prognostic favorable (2.85e-6)" "unprognostic (4.94e-3)" "unprognostic (2.01e-2)" "unprognostic (3.43e-2)" "unprognostic (1.21e-1)" "unprognostic (5.04e-2)" 1.4 0.2 0.2 3.6 1.0 17.0 5.0 0.1 0.3 2.1 0.7 9.1 4.5 0.7 0.1 0.5 0.5 1.7 1.9 0.2 0.1 0.2 1.0 1.3 4.0 0.6 0.3 1.1 3.3 0.1 0.2 0.2 0.4 4.2 13.5 0.1 38.6 0.7 0.3 1.8 8.4 1.1 0.3 2.9 3.5 1.1 0.6 6.1 0.6 0.4 3.6 2.8 0.3 0.4 13.2 4.4 0.9 0.2 1.7 5.1 10.1 1.4 1.2 3.7 5.1 8.9 2.6 19.5 0.5 5.1 0.2 0.0 14.7 0.0 5.2 29.4 3.3 17.1 0.0 0.0 2.9 23.9 0.4 3.9 1.5 11.4 0.1 0.0 10.7 18.4 12.0 8.4 4.8 10.7 22.0 11.6 5.3 24.6 0.0 11.7 11.9 3.8 0.0 16.6 9.5 2.2 3.0 3.1 0.1 0.9 0.6 13.4 15.6 0.0 15.3 12.6 0.0 0.1 0.0 24.9 0.0 11.1 0.0 16.9 1.0 2.5 5.0 1.0 5.0 2.6 2.5 4.0 0.8 0.9 1.4 2.5 1.1 3.5 0.2 0.3 1.0 1.7 0.2 1.0 0.1 0.3 0.2 0.1 0.6 0.3 0.4 0.3 0.6 0.4 0.9 0.0 0.6 1.0 6.1 0.0 1.3 0.0 0.6 1.1 12.8 9.4 3.8 0.0 3.1 0.0 2.1 0.1 14.9 4.3 0.0 1.6 1.5 0.4 5.5 1.2 0.0 3.0 3.4 2.9 0.6 3.1 6.1 0.3 0.0 13.2 2.2 0.5 2.0 0.0 5.5 46.0 0.0 2.5 0.0 2.9 1.8 3.1 0.0 4.7 3.2 0.1 8.2 0.0 0.6 1.9 5.3 4.5 8.6 4.7 3.2 0.2 2.9 0.2 0.0 4.2 2.0 1.2 2.9 0.2 0.0 0.0 12.1 2.6 8.1 1.8 CRCT1 "C1orf42, NICE-1" ENSG00000169509 "Cysteine rich C-terminal 1" Q9UGL9 1 152514482-152516008 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 579.1;esophagus: 1822.3;vagina: 867.6" "Cell type enhanced" "Detected in some" "Ductal cells: 22.7;Pancreatic endocrine cells: 125.4;Squamous epithelial cells: 44.1;Suprabasal keratinocytes: 37.1" "Cancer enriched" "Detected in many" 4 "head and neck cancer: 68.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 6 "CAPAN-2: 5.0" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "unprognostic (3.01e-2)" "unprognostic (6.92e-2)" "unprognostic (2.86e-2)" "unprognostic (3.30e-1)" "prognostic unfavorable (7.03e-4)" "unprognostic (1.56e-2)" "unprognostic (1.46e-1)" 0.6 0.3 0.0 0.0 0.0 0.0 4.1 0.0 0.0 579.1 0.0 0.3 0.0 0.3 0.0 1822.3 0.2 0.0 0.3 0.0 0.0 0.2 0.9 0.2 0.0 0.0 0.0 0.4 1.2 0.0 0.7 0.2 0.0 0.3 0.0 0.0 312.0 0.0 1.0 292.2 0.4 0.0 0.0 0.3 1.2 0.2 0.0 0.0 0.2 0.0 18.4 0.4 867.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.5 0.6 0.0 0.0 0.0 1.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 22.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 4.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.2 0.0 0.9 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 125.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 44.1 37.1 0.0 0.0 0.0 0.0 2.0 CSNK2A2 "CK2alpha', CSNK2A1" ENSG00000070770 "Casein kinase 2 alpha 2" P19784 16 58157907-58198106 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, Transcription, Transcription regulation, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 112.7" "Group enriched" "Detected in all" 5 "Early spermatids: 227.4;Late spermatids: 281.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 92000 "Cluster 46: Basophils - DNA binding" "Cluster 27: Brain & Skin - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 34: Spermatids - Unknown function" "unprognostic (9.49e-2)" "unprognostic (1.87e-1)" "unprognostic (5.45e-2)" "unprognostic (1.23e-1)" "unprognostic (2.08e-1)" "prognostic unfavorable (1.40e-5)" "prognostic unfavorable (1.80e-4)" "unprognostic (6.84e-3)" "unprognostic (2.93e-3)" "unprognostic (2.40e-1)" "unprognostic (3.03e-2)" "unprognostic (1.63e-1)" "unprognostic (5.89e-2)" "unprognostic (2.06e-3)" "unprognostic (7.07e-2)" "unprognostic (3.23e-1)" "unprognostic (3.14e-2)" 21.0 14.1 19.3 9.0 20.2 6.4 19.0 18.9 22.1 23.0 23.7 32.1 10.0 21.0 29.0 15.7 20.3 14.1 21.2 20.0 19.7 17.3 15.9 16.2 14.2 19.1 20.4 32.4 34.2 23.9 15.7 15.5 19.2 15.5 12.4 13.5 17.0 16.7 41.1 64.8 14.2 21.9 19.8 12.6 27.9 112.7 20.3 18.3 18.0 26.8 17.3 24.2 19.6 19.9 28.1 35.3 24.5 19.1 46.2 62.5 27.6 24.7 41.8 47.7 30.7 64.0 23.2 44.2 38.8 29.6 18.9 29.2 41.6 37.2 53.4 16.9 28.3 23.4 18.0 56.1 66.5 32.6 20.5 66.9 88.9 33.8 65.9 62.0 45.4 43.6 53.4 15.1 31.0 15.8 41.2 21.9 23.4 16.6 45.7 48.4 38.7 25.7 33.1 28.7 20.5 18.4 39.7 20.3 63.6 41.9 13.9 24.6 33.6 27.8 33.7 23.3 25.7 36.2 30.2 63.2 24.3 21.8 24.4 1.1 0.2 0.3 0.7 0.1 0.4 0.6 1.1 0.4 0.2 0.6 1.8 1.3 0.0 0.7 0.1 1.9 0.0 0.1 19.3 20.2 18.9 22.1 20.0 19.7 19.1 20.4 19.2 19.8 20.3 19.9 30.6 12.8 22.5 19.2 16.7 29.6 10.9 13.0 8.6 24.0 19.3 19.9 24.4 12.8 7.6 9.2 4.2 15.9 28.3 16.4 7.9 14.5 227.4 24.7 37.8 25.8 16.8 10.3 27.7 17.2 26.1 17.7 8.6 29.5 8.2 37.0 19.6 17.0 16.9 18.5 19.1 11.9 4.1 25.5 23.0 281.0 14.3 23.1 12.4 20.6 14.2 25.3 18.6 20.6 26.1 25.0 11.5 19.5 9.2 18.1 16.0 16.3 13.4 21.7 13.1 29.2 23.2 48.1 36.8 12.6 29.0 24.5 20.3 35.6 17.5 23.0 CTNND2 "GT24, NPRAP" ENSG00000169862 "Catenin delta 2" Q9UQB3 5 10971836-11904446 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell adhesion, Transcription, Transcription regulation, Wnt signaling pathway" "Developmental protein" "Autism, Autism spectrum disorder, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 93.8" "Cell type enhanced" "Detected in many" "Astrocytes: 2382.9;Excitatory neurons: 1253.9;Inhibitory neurons: 1124.0;Oligodendrocyte precursor cells: 1418.0;Oligodendrocytes: 433.8" "Cancer enriched" "Detected in many" 16 "glioma: 44.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 19.1;MCF7: 9.0;SK-BR-3: 5.3;U-266/84: 17.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015077, CAB037339, HPA071124" Enhanced Approved "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 16: U-266 - Nucleosome" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoplasm, Cell Junctions" Cytosol "CAB037339: , HPA015077: AB_2669150, HPA071124: " "unprognostic (7.32e-2)" "unprognostic (1.51e-3)" "unprognostic (2.23e-1)" "unprognostic (5.16e-2)" "unprognostic (5.66e-2)" "unprognostic (2.06e-2)" "unprognostic (1.81e-1)" "unprognostic (2.74e-2)" "unprognostic (9.13e-2)" "unprognostic (9.86e-2)" "unprognostic (8.95e-3)" "unprognostic (2.66e-1)" "unprognostic (9.55e-4)" "unprognostic (5.87e-2)" "unprognostic (1.05e-2)" "unprognostic (1.33e-1)" "unprognostic (4.76e-2)" 0.2 0.7 79.2 0.2 79.3 0.0 0.9 49.7 75.7 0.1 15.2 1.1 0.1 0.1 0.3 0.1 0.2 2.6 3.8 84.6 56.7 0.0 0.5 0.7 0.1 93.8 72.6 0.5 15.8 0.0 9.0 0.3 71.5 0.9 0.3 7.0 0.8 0.2 0.1 0.7 0.5 0.1 77.7 3.9 0.6 2.6 83.7 0.2 0.2 0.1 0.0 0.1 0.2 76.1 0.0 0.2 19.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 9.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.2 0.0 0.0 5.3 0.0 0.6 0.0 0.0 0.0 0.0 1.0 0.0 3.4 0.0 17.5 0.0 1.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 79.2 79.3 49.7 75.7 84.6 56.7 93.8 72.6 71.5 77.7 83.7 76.1 0.1 0.0 0.0 2382.9 0.1 0.0 0.1 0.0 0.0 24.0 7.9 4.1 12.7 28.6 0.0 1.8 0.0 0.0 0.0 0.1 3.9 6.5 25.6 0.8 0.1 0.8 4.9 0.0 1253.9 6.1 0.2 0.5 0.0 0.9 0.0 0.0 0.0 0.2 0.1 8.4 1124.0 0.1 0.0 0.0 0.7 31.1 1.5 0.2 0.0 69.3 0.0 33.0 0.0 1418.0 433.8 2.2 0.0 0.0 0.0 2.8 0.0 0.4 0.0 3.6 0.0 3.3 0.3 4.6 5.9 0.0 0.0 0.0 0.1 0.5 0.3 0.1 CYB5A CYB5 ENSG00000166347 "Cytochrome b5 type A" P00167 18 74250846-74291973 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 889.6;liver: 2472.0" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 1371.0;Distal tubular cells: 2156.1;Hepatocytes: 3376.3;Proximal enterocytes: 1856.4;Proximal tubular cells: 3630.6" "Cancer enhanced" "Detected in all" "liver cancer: 43.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 1117.0;RT4: 513.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006333, HPA047548, HPA058547" Enhanced Enhanced Vesicles,Cytosol No No 1400000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Cytosol" "CAB006333: , HPA047548: AB_2680084, HPA058547: AB_2683750" "unprognostic (1.88e-1)" "unprognostic (1.28e-1)" "prognostic favorable (5.23e-4)" "unprognostic (1.08e-2)" "unprognostic (1.41e-1)" "unprognostic (9.14e-2)" "prognostic favorable (4.15e-4)" "unprognostic (7.79e-3)" "unprognostic (1.11e-1)" "unprognostic (3.33e-2)" "unprognostic (2.68e-2)" "unprognostic (1.65e-2)" "unprognostic (1.17e-1)" "unprognostic (1.95e-1)" "unprognostic (1.75e-1)" "unprognostic (4.64e-2)" "unprognostic (8.54e-2)" 309.5 109.6 38.4 31.2 39.7 25.3 253.5 42.2 45.2 86.0 37.6 146.5 438.2 44.9 176.2 78.1 81.9 301.2 84.8 37.5 38.8 889.6 2472.0 356.6 43.7 43.1 39.7 223.9 461.3 236.0 58.5 81.8 41.9 95.9 103.4 10.3 59.1 122.8 41.4 118.4 381.7 46.7 40.8 75.6 194.8 57.9 40.0 51.6 42.5 42.1 35.2 155.5 68.3 43.5 78.8 130.8 67.4 0.6 1117.0 198.2 89.5 52.6 113.8 111.0 163.8 156.2 82.7 95.6 36.7 97.6 54.4 170.6 0.1 73.1 86.9 179.8 91.7 34.9 65.6 418.1 174.6 67.3 44.1 334.1 57.4 63.0 32.3 66.0 63.6 85.8 58.6 35.0 93.7 140.9 38.3 80.5 30.4 110.0 86.8 93.6 21.9 2.3 111.9 513.2 190.4 79.7 51.4 137.1 65.8 56.6 271.5 63.7 57.9 0.6 85.8 26.6 68.1 24.6 109.2 30.3 67.0 19.2 64.3 4.1 29.5 7.5 51.3 36.3 116.2 93.7 55.6 60.2 53.7 112.7 54.5 68.6 3.7 36.3 45.7 47.8 48.8 43.2 38.4 39.7 42.2 45.2 37.5 38.8 43.1 39.7 41.9 40.8 40.0 43.5 169.7 637.8 1371.0 11.4 76.0 98.0 82.1 368.6 50.7 9.9 345.8 213.2 90.7 836.4 1053.2 842.4 4.2 229.3 29.4 197.0 2156.1 239.4 7.5 163.1 76.6 119.9 164.2 180.0 13.1 504.6 169.8 141.4 208.9 345.6 39.9 55.0 177.4 3376.3 97.4 8.4 12.6 236.5 457.7 128.6 72.9 26.7 158.1 60.8 90.7 10.3 224.1 39.2 32.0 14.1 22.7 266.7 358.9 149.7 33.4 142.0 1856.4 3630.6 619.5 14.0 52.6 49.6 85.0 15.3 42.0 141.2 223.9 44.5 52.6 1123.6 329.9 220.7 CYB5R1 "humb5R2, NQO3A2" ENSG00000159348 "Cytochrome b5 reductase 1" Q9UHQ9 1 202961873-202967275 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 605.2" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 187.2;Extravillous trophoblasts: 196.5;Syncytiotrophoblasts: 293.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HaCaT: 187.3;hTCEpi: 188.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010641, HPA014147" Enhanced Approved Mitochondria,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 38: Extravillous trophoblasts - Unknown function" Mitochondria Cytosol "HPA010641: AB_1078600, HPA014147: AB_1847370" "unprognostic (6.36e-2)" "unprognostic (8.51e-2)" "unprognostic (1.16e-2)" "prognostic favorable (1.14e-4)" "unprognostic (1.86e-2)" "unprognostic (4.34e-2)" "unprognostic (8.46e-2)" "unprognostic (1.28e-1)" "unprognostic (4.03e-1)" "unprognostic (1.03e-1)" "unprognostic (5.79e-2)" "unprognostic (2.89e-1)" "unprognostic (1.73e-2)" "unprognostic (2.33e-1)" "unprognostic (6.14e-2)" "unprognostic (2.37e-3)" "unprognostic (1.69e-1)" 38.6 57.3 37.4 23.0 38.8 19.7 43.7 41.1 40.5 49.7 57.3 35.7 19.3 41.2 131.4 61.6 68.2 27.2 154.8 38.3 48.0 64.5 50.2 44.0 25.2 45.4 49.4 41.7 45.1 82.9 46.1 66.6 55.7 41.1 21.2 34.3 56.9 40.0 605.2 123.8 25.7 37.5 39.9 39.1 92.8 50.7 41.4 40.1 40.5 308.0 38.8 52.7 45.8 43.6 34.8 21.3 18.3 37.7 166.0 37.9 178.5 68.3 63.4 43.2 38.4 17.5 39.9 21.5 56.5 68.1 24.0 187.3 14.9 58.0 28.2 31.2 37.8 12.4 24.0 20.4 59.7 10.5 29.6 61.2 188.3 47.5 25.8 36.4 28.9 25.8 37.0 37.6 157.8 40.4 13.6 9.5 12.1 31.0 40.1 21.9 87.6 45.7 41.1 40.8 15.7 19.1 38.0 124.0 57.4 39.4 57.7 23.4 28.5 49.0 20.8 18.7 38.3 34.9 44.5 10.0 53.6 16.2 37.1 24.4 56.7 46.6 27.4 42.6 36.3 23.4 30.9 28.9 37.6 35.0 41.9 29.6 46.0 32.2 29.4 25.9 34.2 52.6 37.4 38.8 41.1 40.5 38.3 48.0 45.4 49.4 55.7 39.9 41.4 43.6 33.0 22.4 29.8 10.1 15.5 187.2 38.5 89.5 42.1 21.0 46.1 41.9 119.3 37.1 60.5 29.5 29.2 171.1 15.8 10.6 7.9 38.3 5.0 58.7 17.3 30.0 19.2 30.7 8.9 48.3 196.5 28.9 31.6 34.9 28.5 13.6 32.9 44.6 63.5 10.1 11.3 10.8 105.8 45.4 29.7 8.6 29.8 39.5 64.0 8.4 20.9 65.9 11.3 11.6 8.1 72.8 11.3 31.2 12.5 25.8 16.0 38.9 75.9 35.0 13.1 49.1 30.0 23.0 4.3 40.6 157.4 293.5 19.5 27.9 14.7 48.2 CYP4F8 ENSG00000186526 "Cytochrome P450 family 4 subfamily F member 8" P98187 19 15615218-15630639 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "seminal vesicle: 215.6" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 1.2;Breast glandular cells: 1.7;granulocytes: 1.3;NK-cells: 1.0;Prostatic glandular cells: 1.3;Skeletal myocytes: 1.7;Urothelial cells: 2.5" "Cancer enhanced" "Detected in some" "urothelial cancer: 10.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SK-BR-3: 1.1" "Low region specificity" "Detected in all" HPA058960 Approved NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "HPA058960: AB_2683862" "unprognostic (1.70e-2)" "unprognostic (5.46e-3)" "unprognostic (3.21e-2)" "unprognostic (3.97e-6)" "unprognostic (3.51e-3)" "unprognostic (2.72e-1)" "unprognostic (1.15e-1)" "unprognostic (8.25e-2)" "unprognostic (1.15e-2)" "unprognostic (1.02e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.8 0.0 0.0 0.2 215.6 0.0 12.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.4 1.7 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.5 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.3 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.9 0.0 0.3 0.0 0.0 0.1 0.1 1.0 0.0 0.0 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.7 0.0 1.7 0.2 0.0 0.2 0.0 0.0 0.1 0.2 0.0 0.3 2.5 DCD "AIDD, DCD-1, DSEP, HCAP, PIF" ENSG00000161634 Dermcidin P81605 12 54644589-54648493 "Plasma proteins, Predicted secreted proteins, Transporters" "Antibiotic, Antimicrobial, Fungicide, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "skin 1: 2476.8" "Cell type enriched" "Detected in some" 355 "Melanocytes: 8167.8" "Cancer enriched" "Detected in some" 9 "breast cancer: 91.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in single" "Karpas-707: 1.0" HPA063967 Enhanced "Secreted in other tissues" NA NA 410000000 "Cluster 42: Non-specific - Transcription" "Cluster 61: Skin - Cornification" "Cluster 2: Karpas-707 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" "HPA063967: AB_2685163" "unprognostic (3.55e-2)" "unprognostic (1.61e-1)" 100.2 0.4 3.5 0.3 3.3 1.1 354.3 3.4 5.4 0.3 3.8 0.7 0.2 0.7 0.9 0.5 0.2 0.8 1.3 3.5 3.3 0.2 0.9 0.6 0.2 3.3 3.6 0.4 1.0 0.0 0.5 0.1 3.5 0.4 0.2 0.5 0.5 0.1 14.0 2476.8 0.7 0.1 3.0 0.4 0.7 1.1 3.2 0.3 0.5 0.0 0.2 0.2 0.7 4.1 0.2 0.3 0.4 0.4 0.3 0.4 0.4 0.5 0.1 0.0 0.2 0.0 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.6 0.4 0.0 0.0 0.1 0.2 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.2 1.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.5 0.2 0.0 0.2 0.1 0.3 0.2 0.2 0.0 0.2 0.2 0.1 0.0 0.0 0.2 0.0 0.1 0.1 0.1 1.9 0.4 0.5 0.4 0.3 0.6 0.5 0.4 0.3 0.2 0.4 0.5 0.5 1.1 0.9 0.7 0.5 0.6 0.2 3.5 3.3 3.4 5.4 3.5 3.3 3.3 3.6 3.5 3.0 3.2 4.1 0.0 0.0 0.0 0.0 0.0 13.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.8 0.1 0.0 0.0 8167.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.5 0.4 0.2 0.0 23.0 0.0 1.0 0.0 0.0 0.0 DDA1 "C19orf58, MGC2594, PCIA1" ENSG00000130311 "DET1 and DDB1 associated 1" Q9BW61 19 17309518-17323298 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 416.9;Syncytiotrophoblasts: 253.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042134, HPA055272" Approved Approved Nucleoplasm,Nucleoli No No "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Nucleoli" "HPA042134: AB_10794169, HPA055272: AB_2682767" "unprognostic (1.30e-1)" "unprognostic (6.35e-3)" "unprognostic (3.13e-2)" "unprognostic (1.49e-3)" "unprognostic (5.38e-2)" "unprognostic (1.26e-2)" "unprognostic (3.41e-2)" "unprognostic (4.28e-2)" "unprognostic (1.92e-1)" "unprognostic (2.55e-2)" "unprognostic (1.47e-1)" "unprognostic (8.55e-2)" "unprognostic (1.48e-1)" "unprognostic (4.38e-2)" "unprognostic (6.33e-2)" "unprognostic (1.45e-1)" "unprognostic (3.15e-3)" 7.9 11.5 15.8 5.1 14.4 7.1 7.8 12.2 19.9 7.8 10.4 11.5 5.7 8.6 3.4 10.9 8.4 4.0 12.0 14.7 15.3 9.8 10.9 9.6 6.2 14.0 15.0 7.3 6.8 6.1 8.0 8.0 14.4 10.0 4.8 3.8 8.7 5.4 9.5 13.0 11.2 4.2 13.1 9.9 10.1 10.1 15.2 7.3 7.9 5.0 4.7 9.3 8.0 13.2 15.6 13.5 10.1 8.2 10.5 7.5 15.6 10.1 13.0 15.4 14.1 12.0 13.8 6.0 13.7 10.6 7.3 13.2 7.5 15.0 7.8 9.9 19.4 7.2 11.1 11.5 12.5 8.3 14.2 11.5 17.5 9.3 8.7 9.5 9.1 13.9 8.9 10.7 8.4 7.8 17.5 12.7 11.7 16.0 22.3 11.0 7.8 10.3 12.6 11.5 10.4 15.2 7.3 17.8 9.5 6.1 9.0 11.6 13.7 10.6 8.7 26.9 14.6 12.8 18.2 8.6 23.3 14.4 10.6 3.0 3.8 6.4 4.2 4.3 3.6 3.7 3.5 4.2 3.2 3.2 3.9 3.9 4.0 3.4 3.8 6.8 4.8 3.4 15.8 14.4 12.2 19.9 14.7 15.3 14.0 15.0 14.4 13.1 15.2 13.2 24.4 28.9 14.1 13.4 26.3 54.6 38.6 84.0 30.1 18.4 41.8 30.5 17.1 11.5 54.2 27.6 12.5 140.5 38.5 70.4 39.2 77.2 416.9 48.6 32.8 26.4 20.3 29.9 10.4 46.4 152.8 26.8 34.7 53.7 38.7 25.2 20.3 26.3 65.0 13.5 9.8 43.4 54.9 22.4 36.8 130.3 22.4 34.2 30.2 7.5 57.2 34.1 58.7 4.5 10.8 139.6 79.9 27.1 31.8 41.4 47.4 55.1 43.7 19.0 19.7 19.5 36.0 107.7 40.0 36.8 61.8 253.5 34.2 31.5 28.6 89.5 DDC AADC ENSG00000132437 "Dopa decarboxylase" P20711 7 50458436-50565405 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Catecholamine biosynthesis" "Decarboxylase, Lyase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 165.8;kidney: 314.9;retina: 175.6" "Group enriched" "Detected in many" 4 "Enteroendocrine cells: 410.3;Proximal enterocytes: 391.5;Proximal tubular cells: 429.5;Rod photoreceptor cells: 498.9" "Group enriched" "Detected in many" 5 "colorectal cancer: 23.5;liver cancer: 13.4;pancreatic cancer: 6.4;renal cancer: 18.7;stomach cancer: 9.9" "Group enriched" "Detected in many" 9 "midbrain: 86.3;pons: 29.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "CACO-2: 54.5;Hep G2: 49.3;OE19: 83.6;SCLC-21H: 130.9;SH-SY5Y: 135.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "midbrain: 74.5;pons: 29.4" HPA017742 Enhanced Approved "Actin filaments" NA NA 120000 "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Actin filaments" "HPA017742: AB_1847832" "unprognostic (1.04e-1)" "unprognostic (3.68e-2)" "unprognostic (2.57e-2)" "unprognostic (3.49e-5)" "unprognostic (1.17e-1)" "unprognostic (1.03e-1)" "unprognostic (1.28e-1)" "unprognostic (5.15e-2)" "unprognostic (4.69e-2)" "unprognostic (5.44e-2)" "unprognostic (9.36e-3)" "unprognostic (5.24e-2)" "unprognostic (1.76e-3)" "unprognostic (1.60e-1)" "unprognostic (3.55e-1)" "unprognostic (7.65e-2)" "unprognostic (1.16e-1)" 0.5 48.9 0.1 2.3 0.7 0.0 1.0 0.0 0.6 0.0 0.2 36.5 154.8 0.0 9.1 0.1 0.0 0.1 0.0 0.2 2.2 314.9 54.6 2.0 0.1 6.1 86.3 0.8 15.8 0.0 0.0 0.0 29.4 0.6 37.5 175.6 0.0 0.0 0.0 0.1 165.8 1.7 0.0 0.1 18.1 1.5 1.9 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.0 1.7 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 54.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 49.3 0.0 0.0 11.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.1 83.6 0.0 0.0 0.0 0.7 1.3 0.0 130.9 135.9 0.0 4.4 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.6 0.2 2.2 6.1 86.3 29.4 0.0 1.9 0.2 0.0 0.0 12.2 0.0 2.5 0.0 0.0 0.0 0.0 89.3 0.1 0.1 0.4 2.8 0.6 3.7 41.7 0.0 0.0 34.4 25.4 0.1 6.6 0.1 0.0 1.8 410.3 0.0 0.3 0.9 0.1 0.1 0.0 0.4 0.0 0.0 1.1 67.2 0.1 3.3 0.4 67.8 0.0 1.3 0.0 5.4 0.0 2.5 0.0 0.0 0.0 45.1 0.0 0.0 0.1 0.2 31.8 0.0 0.0 0.3 391.5 429.5 0.0 498.9 0.0 0.0 0.0 4.0 0.4 0.0 0.0 0.1 1.3 0.1 88.7 0.2 DDX31 "FLJ13633, FLJ14578, FLJ23349, PPP1R25" ENSG00000125485 "DEAD-box helicase 31" Q9H8H2 9 132592997-132670401 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 26.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020891 Supported "Nucleoli,Golgi apparatus,Vesicles" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoli "Golgi apparatus, Vesicles" "HPA020891: " "unprognostic (5.71e-2)" "unprognostic (1.76e-2)" "unprognostic (2.56e-1)" "unprognostic (7.91e-2)" "unprognostic (5.79e-2)" "unprognostic (9.94e-2)" "prognostic unfavorable (1.68e-7)" "unprognostic (1.34e-1)" "unprognostic (2.02e-2)" "unprognostic (1.66e-1)" "unprognostic (3.90e-2)" "unprognostic (9.57e-3)" "unprognostic (4.57e-3)" "unprognostic (2.24e-2)" "unprognostic (1.22e-1)" "unprognostic (1.38e-1)" "unprognostic (2.03e-1)" 3.9 3.8 3.3 5.3 3.9 4.2 6.3 8.8 3.2 4.8 4.0 3.9 3.1 4.5 5.0 5.7 5.2 3.6 3.3 2.8 3.7 6.0 5.5 4.5 6.6 5.1 3.8 9.9 5.8 5.4 4.2 3.5 5.7 5.4 4.7 3.2 8.2 4.3 6.1 8.4 4.2 4.2 2.9 4.8 4.0 6.0 3.6 5.5 13.8 4.2 7.2 5.2 4.9 4.7 12.4 22.2 10.8 14.4 12.4 11.1 20.4 12.9 12.2 19.2 14.5 24.9 24.1 29.9 11.2 11.7 20.8 33.5 32.8 14.6 15.4 18.4 12.3 16.4 19.5 13.1 14.9 29.7 12.8 9.9 19.5 19.7 27.5 7.5 12.7 22.1 30.6 11.4 16.1 26.3 20.6 15.9 26.2 35.4 22.2 21.4 19.3 34.6 17.5 11.4 18.8 13.5 23.4 20.2 18.0 12.2 42.8 8.4 11.1 32.5 15.0 18.7 19.8 5.5 18.8 23.5 12.0 18.2 25.2 0.0 1.1 1.2 3.1 1.6 2.4 2.1 2.9 2.4 2.5 2.7 3.6 2.7 0.2 2.0 1.1 1.6 2.0 1.7 3.3 3.9 8.8 3.2 2.8 3.7 5.1 3.8 5.7 2.9 3.6 4.7 3.3 6.4 6.0 16.6 7.2 5.6 4.5 3.0 9.1 4.3 5.9 8.1 4.4 0.0 10.2 7.3 4.2 5.7 4.7 3.6 1.9 6.2 4.1 3.9 6.6 3.6 24.6 1.7 9.7 5.4 6.8 4.4 4.1 4.6 1.3 6.1 2.9 4.1 5.2 1.7 13.9 5.8 6.1 2.9 1.8 3.0 18.0 2.9 1.8 5.6 4.5 1.7 8.2 26.7 17.1 5.9 1.2 13.2 5.7 5.8 0.7 7.1 5.7 3.7 0.0 4.1 3.4 14.0 13.7 8.8 6.3 3.0 5.0 5.7 6.1 3.5 DEGS1 "DEGS-1, Des-1, DES1, FADS7, MLD" ENSG00000143753 "Delta 4-desaturase, sphingolipid 1" O15121 1 224175756-224193441 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "skin 1: 535.6" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 246.0;Cytotrophoblasts: 281.8;Suprabasal keratinocytes: 320.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076422 Supported Mitochondria NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 61: Skin - Cornification" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "HPA076422: AB_2686799" "unprognostic (2.34e-2)" "unprognostic (6.91e-2)" "unprognostic (2.48e-2)" "prognostic unfavorable (7.74e-5)" "unprognostic (1.50e-1)" "unprognostic (2.74e-1)" "prognostic unfavorable (4.29e-5)" "unprognostic (7.70e-2)" "unprognostic (2.31e-1)" "unprognostic (3.20e-1)" "unprognostic (3.63e-1)" "unprognostic (1.27e-1)" "prognostic unfavorable (6.83e-7)" "unprognostic (2.87e-1)" "unprognostic (1.61e-1)" "unprognostic (3.86e-2)" "prognostic unfavorable (2.53e-4)" 60.3 31.0 30.3 44.9 33.1 69.5 61.9 35.0 36.2 53.4 42.5 50.8 47.0 44.5 29.5 48.6 34.4 40.5 43.8 31.3 35.6 38.1 35.7 49.1 48.0 36.6 35.2 27.1 22.5 31.5 34.8 128.7 35.9 83.2 27.2 20.8 38.7 58.6 20.9 535.6 33.4 70.9 37.9 38.7 38.6 22.7 34.0 34.2 52.3 23.3 50.9 48.4 72.7 44.5 72.8 50.7 65.2 49.5 275.7 181.1 51.2 201.1 223.8 137.5 164.2 47.1 55.2 58.0 252.4 181.0 82.4 76.3 76.5 67.9 153.0 84.2 141.5 41.7 51.1 29.2 167.9 84.2 86.1 177.4 153.6 125.5 69.9 143.0 140.4 31.4 62.8 61.8 181.2 27.5 43.2 46.9 83.3 40.0 76.1 38.8 92.4 37.5 181.1 19.8 42.3 69.8 106.6 169.4 110.4 118.8 57.1 123.4 125.7 133.4 41.4 153.1 197.5 44.5 55.3 52.8 141.9 41.7 154.2 104.6 61.4 120.3 30.9 67.8 59.8 58.2 52.7 43.3 104.4 74.3 40.7 37.0 67.7 43.9 48.7 34.9 59.0 52.8 30.3 33.1 35.0 36.2 31.3 35.6 36.6 35.2 35.9 37.9 34.0 44.5 71.7 83.3 29.3 13.4 69.9 246.0 44.0 33.6 89.4 31.2 40.7 38.4 20.8 10.0 19.8 11.0 14.6 281.8 40.5 4.0 13.7 34.9 27.9 54.0 90.2 66.7 14.9 18.7 17.4 43.3 48.3 77.7 21.4 146.1 106.5 21.3 55.6 20.8 93.0 18.5 20.4 6.2 34.6 57.8 90.5 13.6 63.0 72.8 69.4 20.6 57.1 26.0 10.3 25.6 32.1 29.5 5.9 79.4 50.1 44.2 20.1 29.7 20.1 18.4 105.2 42.7 89.1 84.3 44.0 50.4 320.4 198.9 58.9 43.7 6.6 13.7 DEPDC1 "DEP.8, DEPDC1A, FLJ20354, SDP35" ENSG00000024526 "DEP domain containing 1" Q5TB30 1 68474152-68497221 "Predicted intracellular proteins" "Transcription, Transcription regulation" "GTPase activation, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.0;lymphoid tissue: 8.1;testis: 8.1" "Cell type enhanced" "Detected in many" "Early spermatids: 44.9;Erythroid cells: 31.8;Extravillous trophoblasts: 35.2;Late spermatids: 73.0;Spermatocytes: 86.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" CAB017845 Approved Supported "Nucleoplasm,Nucleoli fibrillar center" NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nucleoli fibrillar center" "CAB017845: " "unprognostic (2.73e-1)" "unprognostic (7.40e-2)" "prognostic favorable (8.70e-5)" "unprognostic (1.23e-3)" "unprognostic (3.06e-1)" "unprognostic (7.73e-3)" "unprognostic (4.37e-6)" "unprognostic (3.39e-3)" "unprognostic (1.57e-3)" "unprognostic (8.59e-2)" "unprognostic (9.04e-6)" "unprognostic (2.18e-1)" "unprognostic (0.00e+0)" "unprognostic (2.39e-2)" "unprognostic (2.27e-1)" "unprognostic (2.83e-2)" "unprognostic (1.11e-1)" 0.3 0.1 0.0 2.6 0.0 5.0 0.6 0.0 0.1 0.4 0.0 2.9 2.5 0.5 0.1 2.4 0.1 0.5 0.1 0.1 0.0 0.0 0.4 0.2 4.8 0.0 0.1 0.0 0.0 0.2 0.0 3.2 0.1 2.1 3.5 0.0 0.3 0.1 0.0 1.6 2.4 1.5 0.0 0.6 1.2 8.1 0.2 8.1 0.3 0.2 4.8 0.9 0.7 0.2 47.2 21.5 40.0 18.5 2.5 5.6 31.3 58.9 26.9 49.1 42.1 17.9 19.3 0.0 42.8 24.4 78.6 30.8 58.6 30.7 82.4 41.2 38.2 38.3 35.9 10.5 0.6 33.4 0.0 2.1 1.6 56.3 31.2 10.0 36.0 16.5 26.6 36.1 88.3 10.7 0.1 12.5 34.6 19.5 28.9 0.0 118.7 15.3 19.8 12.7 44.8 20.7 59.0 24.9 30.3 25.6 22.5 16.6 21.3 31.5 35.5 56.0 69.2 22.5 52.2 0.5 29.7 11.4 65.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.2 0.2 0.4 0.0 0.0 0.3 2.0 3.3 0.8 3.3 1.2 0.4 1.3 1.8 0.8 0.0 0.5 1.8 0.0 20.6 0.4 2.1 0.0 0.2 44.9 4.0 1.6 1.6 0.0 31.8 0.5 0.0 35.2 4.4 8.2 2.0 0.0 17.5 2.2 1.2 8.6 0.0 2.2 5.3 4.1 3.5 1.0 73.0 0.3 1.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.4 6.9 2.2 0.5 0.1 0.9 0.2 0.0 0.6 4.0 86.8 19.6 12.2 1.3 2.9 1.6 0.5 8.8 1.7 DEPDC1B "BRCC3, XTP1" ENSG00000035499 "DEP domain containing 1B" Q8WUY9 5 60596912-60700190 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 11.1;gallbladder: 21.0;lymphoid tissue: 20.7;testis: 12.6" "Cell type enhanced" "Detected in many" "Cholangiocytes: 18.6;Erythroid cells: 23.8;Extravillous trophoblasts: 21.6;Spermatocytes: 37.2;Syncytiotrophoblasts: 46.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "T-reg: 3.2" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA038255, HPA072558" Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA Yes "Cluster 35: T-regs - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA038255: AB_10669521, HPA072558: AB_2686534" "unprognostic (1.38e-1)" "unprognostic (1.99e-2)" "prognostic favorable (2.42e-4)" "prognostic unfavorable (8.55e-4)" "unprognostic (2.23e-1)" "unprognostic (7.93e-2)" "prognostic unfavorable (3.08e-4)" "prognostic unfavorable (6.93e-5)" "unprognostic (2.13e-2)" "unprognostic (8.14e-2)" "unprognostic (1.47e-3)" "unprognostic (2.44e-2)" "unprognostic (1.11e-16)" "unprognostic (1.00e-1)" "unprognostic (1.40e-1)" "unprognostic (1.53e-1)" "unprognostic (8.62e-2)" 0.3 0.2 0.4 3.9 0.7 11.1 0.9 0.5 0.5 0.6 0.1 4.1 6.0 0.6 0.0 2.5 0.2 21.0 0.1 0.3 0.6 2.9 0.4 0.4 9.1 1.2 0.5 0.2 0.1 0.0 0.0 7.5 1.4 0.2 5.5 0.1 0.5 0.1 0.0 2.1 6.4 0.9 0.6 1.6 1.4 12.6 0.6 20.7 1.2 0.0 9.7 1.0 1.1 1.5 61.0 20.3 60.5 37.2 1.3 1.9 66.2 16.1 10.9 27.7 35.8 34.0 37.5 34.6 38.5 5.0 36.0 19.8 49.2 36.1 36.9 49.5 35.5 43.3 22.7 42.6 1.0 36.7 40.3 1.2 3.7 9.0 12.9 5.4 26.1 36.3 31.4 45.8 24.7 38.0 59.8 31.9 44.7 13.0 32.6 65.4 49.2 29.4 22.8 29.9 33.6 15.4 37.7 13.4 17.7 27.0 24.9 28.8 12.1 11.7 34.2 9.5 41.6 23.0 43.3 68.0 14.7 53.2 33.3 1.5 0.1 0.9 0.2 0.0 0.2 0.4 1.0 0.7 0.3 0.0 0.1 0.1 0.0 0.6 0.0 0.0 3.2 0.4 0.4 0.7 0.5 0.5 0.3 0.6 1.2 0.5 1.4 0.6 0.6 1.5 0.2 0.0 1.8 0.0 1.9 4.7 1.0 1.5 0.0 0.1 0.5 0.8 0.1 18.6 0.3 0.0 0.0 7.4 1.1 3.1 0.0 0.3 1.9 3.3 1.4 0.9 0.0 23.8 5.5 0.2 21.6 1.1 2.6 11.7 3.8 5.2 0.0 0.3 6.4 0.0 1.7 2.3 0.0 1.6 2.9 2.4 0.3 1.9 0.0 4.7 0.1 0.2 0.0 2.0 7.0 0.9 5.8 0.0 15.9 0.7 3.7 1.0 0.1 0.1 6.6 0.3 1.4 37.2 12.7 5.8 2.0 46.9 4.5 0.6 7.9 0.9 DES "CMD1I, CSM1, CSM2" ENSG00000175084 Desmin P17661 2 219418377-219426734 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Muscle protein" "Cancer-related genes, Cardiomyopathy, Desmin-related myopathy, Disease variant, Limb-girdle muscular dystrophy, Myofibrillar myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 13020.7;intestine: 8627.2;skeletal muscle: 16532.0" "Cell type enriched" "Detected in many" 5 "Cardiomyocytes: 2531.9" "Cancer enhanced" "Detected in all" "prostate cancer: 562.1;stomach cancer: 400.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HSkMC: 70.2;LHCN-M2: 145.3;NB-4: 39.5;RH-30: 333.1" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 5 "midbrain: 29.5" "CAB000034, HPA018803" Enhanced Supported "Intermediate filaments" NA NA 1600000 "Cluster 7: Monocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" "Intermediate filaments" "CAB000034: , HPA018803: AB_1847616" "unprognostic (1.75e-1)" "unprognostic (1.95e-3)" "unprognostic (3.43e-2)" "unprognostic (8.76e-2)" "unprognostic (7.75e-3)" "unprognostic (6.61e-3)" "unprognostic (1.55e-1)" "unprognostic (2.72e-2)" "unprognostic (4.67e-1)" "unprognostic (3.84e-2)" "unprognostic (2.57e-1)" "unprognostic (7.43e-2)" "prognostic unfavorable (5.08e-4)" "unprognostic (3.49e-2)" "unprognostic (1.34e-1)" "unprognostic (1.22e-1)" "unprognostic (9.25e-3)" 235.3 57.1 2.1 436.2 4.9 1.1 51.2 2.1 9.6 504.3 5.0 8627.2 291.3 3015.2 86.0 1481.2 1085.0 452.1 13020.7 2.4 2.5 37.6 15.5 173.9 7.2 3.4 2.5 171.8 14.6 0.5 8.4 52.7 2.4 2218.8 245.6 0.0 255.3 2253.1 16532.0 152.4 1343.5 2557.5 2.1 25.2 1965.6 16.1 2.6 3.2 66.2 5753.8 1.2 4761.8 669.4 2.4 0.0 0.0 0.1 0.0 0.0 2.2 5.3 0.2 0.0 0.1 0.1 0.5 0.0 0.0 9.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.2 17.0 0.1 1.3 70.2 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 145.3 0.0 0.0 39.5 0.5 0.0 0.0 0.0 333.1 2.1 0.0 0.0 0.2 1.2 0.0 0.0 0.0 9.2 0.0 5.0 0.0 0.0 0.1 1.7 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.7 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 2.1 4.9 2.1 9.6 2.4 2.5 3.4 2.5 2.4 2.1 2.6 2.4 0.4 0.0 0.0 0.0 0.0 4.1 2.7 0.0 0.0 0.0 0.1 0.0 2531.9 1.5 0.0 0.0 0.0 1.9 0.0 0.4 0.0 0.0 90.6 0.5 6.7 22.7 0.0 0.0 0.1 0.0 5.2 104.6 0.0 0.1 0.0 0.0 1.8 0.0 5.6 0.0 0.0 0.9 0.0 0.0 10.7 71.6 28.9 2.8 12.4 0.0 0.6 0.0 0.0 0.5 0.0 0.5 0.0 50.4 0.0 8.7 0.0 0.1 0.0 0.0 46.0 497.8 210.5 5.0 5.1 0.1 9.8 8.5 2.4 0.0 0.2 2.9 DGAT2L6 "DC3, FLJ25989" ENSG00000184210 "Diacylglycerol O-acyltransferase 2 like 6" Q6ZPD8 X 70177483-70205704 "Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 40 "breast: 2.1;skin 1: 5.8" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "testis cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" "unprognostic (1.90e-2)" "unprognostic (3.08e-1)" "unprognostic (1.43e-3)" "unprognostic (3.47e-3)" "unprognostic (8.60e-2)" "unprognostic (5.82e-2)" "unprognostic (1.63e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 DGKA "DAGK, DAGK1, DGK-alpha" ENSG00000065357 "Diacylglycerol kinase alpha" P23743 12 55927319-55954027 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 101.5;lymphoid tissue: 198.1" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 49.0;Squamous epithelial cells: 40.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Lineage enriched" "Detected in all" 4 "T-cells: 86.9" "Cell line enhanced" "Detected in many" "HBEC3-KT: 130.4;hTERT-HME1: 133.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041645, HPA045462" Approved Approved Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 58: T-cells - T-cell receptor" Vesicles "Nucleoplasm, Mitochondria" "HPA041645: AB_2677595, HPA045462: AB_2679335" "unprognostic (1.12e-3)" "unprognostic (1.43e-2)" "unprognostic (1.62e-2)" "unprognostic (2.63e-2)" "unprognostic (5.23e-2)" "unprognostic (2.04e-1)" "unprognostic (3.62e-1)" "unprognostic (3.31e-2)" "unprognostic (5.28e-2)" "unprognostic (1.94e-1)" "unprognostic (1.82e-2)" "unprognostic (2.46e-1)" "prognostic unfavorable (1.66e-5)" "unprognostic (4.06e-1)" "unprognostic (1.00e-1)" "unprognostic (1.47e-1)" "unprognostic (7.02e-2)" 12.7 12.8 7.6 50.0 9.8 31.9 11.0 6.6 9.2 22.9 7.0 25.6 51.2 13.1 9.9 101.5 11.4 15.8 8.5 7.2 5.2 7.9 3.7 18.6 95.5 5.2 5.0 10.9 14.6 12.0 6.9 14.9 5.3 24.8 26.9 2.8 35.5 9.6 2.3 84.7 64.8 14.1 4.8 53.8 12.4 12.3 5.0 198.1 10.5 4.2 101.8 28.4 39.0 6.8 22.2 13.2 9.3 12.4 22.4 29.0 2.8 47.2 47.8 18.2 13.5 6.9 35.2 13.5 11.1 31.5 6.2 38.7 10.3 130.4 21.4 14.4 2.5 21.1 26.8 3.6 19.1 6.7 20.9 25.1 68.4 25.2 133.9 60.6 37.9 78.8 2.4 18.7 49.4 2.3 54.3 8.6 2.0 18.1 15.5 23.8 2.9 2.0 43.7 60.9 1.6 5.6 15.5 0.9 1.7 23.8 9.3 6.4 34.0 12.0 8.4 2.8 1.7 2.9 1.2 32.4 13.8 17.5 3.4 17.0 7.4 15.3 18.5 5.2 35.5 20.4 70.6 33.0 10.5 16.2 86.9 51.5 13.3 14.1 3.5 10.5 86.7 36.2 7.6 9.8 6.6 9.2 7.2 5.2 5.2 5.0 5.3 4.8 5.0 6.8 4.5 3.2 6.5 1.6 25.7 15.0 9.7 21.1 26.7 1.2 4.0 4.6 2.9 4.3 19.1 5.5 0.0 16.3 12.2 35.4 0.0 5.1 9.4 1.9 6.5 5.3 2.4 11.2 11.2 9.4 4.3 8.2 15.3 3.0 7.0 2.4 4.2 0.2 4.2 0.0 5.2 7.7 2.0 6.9 21.6 7.0 3.7 14.0 0.0 5.6 15.7 2.6 10.3 9.0 0.8 25.3 14.4 3.0 14.8 8.2 49.0 0.3 5.2 0.5 6.6 1.5 4.2 6.6 4.2 40.4 13.9 26.4 37.4 1.6 9.7 20.1 DHRS9 "3alpha-HSD, RDH15, RDHL, RETSDR8, SDR9C4" ENSG00000073737 "Dehydrogenase/reductase 9" Q9BPW9 2 169064789-169096167 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 53.9;intestine: 70.4" "Cell type enhanced" "Detected in many" "Club cells: 229.3;Distal enterocytes: 261.2;Early spermatids: 153.2;Paneth cells: 299.9;Respiratory ciliated cells: 155.9;Syncytiotrophoblasts: 267.5;Urothelial cells: 249.2" "Cancer enhanced" "Detected in many" "pancreatic cancer: 16.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 258.3;eosinophil: 99.2;neutrophil: 77.3" "Lineage enriched" "Detected in many" 10 "granulocytes: 258.3" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 22.8;HUVEC TERT2: 21.5;NB-4: 33.7;THP-1: 98.0;TIME: 49.9;U-2197: 31.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA036491, HPA036667" Approved "Intracellular and membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 43: THP-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA036491: AB_10673498, HPA036667: AB_10670237" "unprognostic (1.15e-1)" "unprognostic (3.82e-3)" "unprognostic (1.15e-1)" "unprognostic (1.85e-1)" "unprognostic (4.80e-2)" "unprognostic (2.35e-1)" "unprognostic (3.24e-2)" "unprognostic (1.40e-1)" "unprognostic (3.18e-1)" "unprognostic (3.62e-4)" "prognostic unfavorable (2.73e-4)" "unprognostic (2.72e-1)" "unprognostic (3.23e-1)" "unprognostic (1.85e-2)" "unprognostic (1.34e-2)" "unprognostic (1.12e-1)" "unprognostic (1.41e-1)" 10.0 0.2 2.2 12.5 2.4 8.5 5.1 3.0 2.6 8.6 1.6 70.4 1.9 1.2 0.9 28.2 1.0 5.7 53.9 2.5 2.3 0.3 3.1 7.1 20.2 4.2 3.2 0.7 0.4 0.2 0.4 2.8 4.3 0.8 46.2 1.2 6.1 0.5 0.3 3.3 5.7 4.2 3.8 7.6 10.8 11.3 3.2 2.2 0.3 0.8 26.8 17.5 10.1 4.5 0.0 0.7 0.0 0.0 2.5 10.2 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.1 0.0 0.0 6.5 1.7 0.0 1.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 8.9 1.0 0.4 0.5 1.3 6.1 22.8 21.5 0.0 1.0 0.0 0.0 0.0 0.1 33.7 0.0 0.3 8.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 98.0 49.9 0.1 0.2 31.4 0.2 0.1 0.0 0.0 0.8 18.9 0.0 258.3 21.0 99.2 0.0 25.0 0.6 6.5 0.0 0.0 21.6 5.0 0.1 0.0 77.3 0.4 5.1 1.6 0.0 5.9 2.2 2.4 3.0 2.6 2.5 2.3 4.2 3.2 4.3 3.8 3.2 4.5 0.3 0.0 1.3 0.0 1.4 1.7 19.3 72.4 0.0 0.0 0.1 0.4 24.4 0.0 229.3 0.0 0.0 2.5 0.0 261.2 0.0 4.6 153.2 0.5 0.0 0.6 1.8 0.8 0.2 25.3 1.3 1.5 7.7 0.1 91.0 0.0 0.0 0.6 25.0 0.0 0.2 51.6 36.7 10.2 38.8 45.5 1.2 16.6 0.0 19.7 3.5 3.9 0.0 0.0 0.2 68.6 299.9 0.4 6.4 6.5 1.5 0.1 155.9 0.1 6.6 0.2 10.9 1.1 0.6 0.3 1.4 267.5 3.8 0.0 8.2 249.2 DLGAP5 "DLG1, DLG7, HURP, KIAA0008" ENSG00000126787 "DLG associated protein 5" Q15398 14 55148112-55191608 "Plasma proteins, Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 29.7;lymphoid tissue: 42.0;testis: 17.4" "Cell type enhanced" "Detected in many" "Erythroid cells: 92.6;Extravillous trophoblasts: 23.1;Plasma cells: 22.1;Spermatocytes: 68.1;Spermatogonia: 31.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "T-reg: 5.4" "Lineage enriched" "Detected in many" 5 "T-cells: 5.4" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA005546 Enhanced Supported "Centriolar satellite,Cytosol" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Centriolar satellite, Cytosol" "HPA005546: AB_1078677" "unprognostic (2.24e-1)" "unprognostic (1.77e-1)" "unprognostic (1.19e-3)" "prognostic unfavorable (4.59e-4)" "unprognostic (1.42e-1)" "unprognostic (1.66e-2)" "prognostic unfavorable (1.52e-6)" "prognostic unfavorable (7.85e-4)" "unprognostic (6.15e-3)" "unprognostic (3.55e-1)" "prognostic unfavorable (9.94e-6)" "unprognostic (4.69e-2)" "unprognostic (0.00e+0)" "unprognostic (1.06e-2)" "unprognostic (3.64e-1)" "unprognostic (1.29e-1)" "unprognostic (1.93e-2)" 0.8 0.3 1.4 8.1 0.9 29.7 1.4 0.4 1.8 0.8 0.6 5.5 5.0 1.3 0.1 5.2 0.4 0.8 0.2 1.0 1.7 0.2 0.7 0.7 17.9 0.7 1.0 0.2 0.1 0.2 0.0 4.1 0.8 0.2 6.7 0.1 0.8 0.1 0.1 3.1 4.6 2.7 0.3 2.6 3.0 17.4 1.1 42.0 0.4 0.0 18.7 2.0 1.5 3.8 144.8 56.8 140.6 63.7 3.3 13.4 43.8 80.3 52.7 115.3 109.3 45.9 75.8 82.1 44.2 46.9 47.4 85.6 91.5 64.0 150.5 101.9 45.7 84.4 49.9 39.3 0.4 82.7 49.3 2.8 2.2 54.8 27.0 18.9 129.0 82.5 70.5 79.8 109.3 69.2 105.0 42.7 72.6 63.3 57.3 80.8 137.9 39.0 37.9 45.2 71.7 40.7 84.8 31.7 30.8 60.6 71.6 31.6 49.6 52.4 133.3 50.6 94.6 19.4 44.9 108.9 35.9 59.6 83.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.9 1.4 0.3 0.0 0.2 0.1 0.2 1.0 0.0 0.0 5.4 0.7 1.4 0.9 0.4 1.8 1.0 1.7 0.7 1.0 0.8 0.3 1.1 3.8 0.1 0.0 0.5 0.0 4.4 1.1 0.7 3.3 0.0 0.0 1.2 0.9 0.4 0.0 1.3 0.0 0.0 11.6 1.4 3.2 0.0 0.4 19.7 7.2 2.6 2.4 0.0 92.6 0.3 0.0 23.1 4.2 7.7 4.5 0.0 15.8 3.9 0.5 10.5 0.0 0.3 3.6 8.2 4.1 1.6 6.0 0.9 3.7 0.0 0.0 0.0 0.0 1.0 0.0 0.3 0.2 0.2 1.2 22.1 0.6 0.3 0.1 1.3 0.0 6.6 0.0 3.8 68.1 31.7 11.6 0.4 1.9 4.0 0.9 6.9 1.4 DMBX1 "OTX3, PAXB" ENSG00000197587 "Diencephalon/mesencephalon homeobox 1" Q8NFW5 1 46489836-46516216 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 7.2" "Cell type enhanced" "Detected in some" "Bipolar cells: 2.3;Cone photoreceptor cells: 2.1;Spermatogonia: 2.0" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "thalamus: 7.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 12.1;CAPAN-2: 4.0;GAMG: 3.1;K-562: 4.0;SiHa: 4.1;T-47d: 3.1" "Group enriched" "Detected in some" 7 "midbrain: 1.5;pons and medulla: 1.0" "Region enhanced" "Detected in some" "thalamus: 4.0" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 56: Bipolar cells - Visual perception" "unprognostic (1.14e-2)" "unprognostic (2.33e-1)" "unprognostic (1.43e-1)" "prognostic unfavorable (7.13e-5)" "unprognostic (2.33e-2)" "unprognostic (8.92e-3)" "unprognostic (1.07e-1)" "unprognostic (5.90e-2)" "unprognostic (2.63e-2)" "unprognostic (1.89e-1)" "unprognostic (2.00e-4)" "unprognostic (1.19e-2)" "unprognostic (2.12e-12)" "unprognostic (7.91e-2)" "unprognostic (1.38e-1)" "unprognostic (1.98e-1)" "unprognostic (3.35e-2)" 0.0 0.0 1.7 0.0 0.0 0.1 0.1 2.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.9 2.8 0.0 0.0 0.1 0.7 0.0 0.6 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 7.2 0.0 0.2 0.0 0.0 0.2 0.0 0.2 1.8 1.0 0.0 12.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 4.0 0.0 0.6 0.0 3.1 1.0 2.3 0.0 0.0 0.8 1.3 0.0 1.5 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 1.2 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 4.1 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.7 0.0 2.7 0.1 0.0 0.8 0.9 2.8 0.6 0.0 7.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 2.3 0.0 0.0 0.3 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.6 2.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 DNAJB2 "CMT2T, HSJ1, HSPF3" ENSG00000135924 "DnaJ heat shock protein family (Hsp40) member B2" P25686 2 219279342-219286898 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Chaperone Neurodegeneration "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 366.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036268 Approved Enhanced "Nuclear membrane" NA NA 9900 "Cluster 52: Eosinophils - Transcription" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 30: Epithelial cell lines - Translation" "Cluster 30: Mammary glandular cells - Lactation" "Nuclear membrane" "HPA036268: AB_10670793" "unprognostic (2.02e-2)" "unprognostic (3.69e-2)" "prognostic unfavorable (1.01e-4)" "unprognostic (2.53e-2)" "unprognostic (1.57e-1)" "unprognostic (2.35e-1)" "unprognostic (1.45e-3)" "unprognostic (5.11e-2)" "unprognostic (2.11e-2)" "unprognostic (1.40e-1)" "unprognostic (1.16e-3)" "unprognostic (7.03e-2)" "unprognostic (4.09e-2)" "unprognostic (4.64e-2)" "unprognostic (1.96e-2)" "unprognostic (5.98e-2)" "unprognostic (5.62e-3)" 41.9 106.9 264.5 17.7 290.6 26.6 45.7 276.0 323.5 63.8 232.0 48.9 23.2 46.2 45.2 54.1 48.2 26.6 85.4 266.6 270.7 81.0 72.1 45.8 26.0 281.8 281.8 65.0 84.8 54.3 112.1 27.1 279.7 73.9 15.8 63.9 62.3 35.5 135.6 108.1 36.0 15.8 269.7 46.7 54.8 86.0 280.5 28.4 71.0 56.5 20.5 52.8 59.0 366.0 34.9 14.2 21.9 20.7 45.6 22.1 29.3 32.8 27.2 29.0 24.2 66.2 21.3 21.4 39.7 31.6 66.3 49.1 27.9 36.3 16.3 45.3 12.2 41.7 28.0 32.0 30.8 7.1 36.5 21.3 103.3 31.8 38.4 51.3 12.9 23.5 7.4 23.7 21.4 18.0 13.0 8.4 12.9 30.2 26.4 13.4 17.9 13.5 31.7 24.5 20.6 26.0 38.0 38.4 64.9 57.5 28.6 14.9 17.5 41.6 82.3 12.0 28.6 26.2 8.4 35.0 42.8 6.5 31.1 0.0 0.4 2.1 0.7 0.4 0.6 0.5 0.7 0.6 0.2 1.7 1.0 0.9 0.4 1.3 1.2 0.6 1.0 0.4 264.5 290.6 276.0 323.5 266.6 270.7 281.8 281.8 279.7 269.7 280.5 366.0 24.6 19.2 31.4 35.6 30.9 28.6 40.9 17.1 9.1 97.9 61.9 33.9 77.4 25.8 18.0 38.6 56.3 36.1 24.0 41.5 78.2 60.0 43.8 43.5 16.2 22.3 53.7 69.9 17.9 33.5 34.7 27.5 22.4 27.9 24.8 22.1 20.7 20.5 28.2 80.8 26.5 47.5 10.2 19.7 28.2 70.9 36.4 28.0 32.0 11.2 21.6 84.8 15.5 16.6 144.2 68.9 23.6 39.1 28.5 39.8 31.7 56.5 39.0 87.3 19.7 27.3 28.3 56.5 20.6 18.9 50.4 69.0 30.2 23.1 25.5 25.8 DNER "bet, UNQ26" ENSG00000187957 "Delta/notch like EGF repeat containing" Q8NFT8 2 229357629-229714555 "Cancer-related genes, Predicted membrane proteins" "Notch signaling pathway" "Activator, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 73.0;brain: 147.5;choroid plexus: 143.8" "Group enriched" "Detected in many" 4 "Bipolar cells: 123.3;Inhibitory neurons: 333.0;Oligodendrocyte precursor cells: 435.8;Oligodendrocytes: 247.7" "Cancer enriched" "Detected in many" 32 "glioma: 73.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "GAMG: 368.0;hTERT-HME1: 149.7;hTERT-RPE1: 409.5;U-138 MG: 252.2;U-87 MG: 149.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017320 Enhanced NA NA 7900000 "Cluster 73: Brain - Neuropeptide signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA017320: AB_1847808" "unprognostic (4.39e-2)" "unprognostic (1.83e-1)" "unprognostic (3.25e-1)" "unprognostic (1.00e-3)" "unprognostic (8.73e-2)" "unprognostic (6.23e-2)" "prognostic unfavorable (1.05e-4)" "unprognostic (4.23e-3)" "unprognostic (2.97e-1)" "unprognostic (1.17e-1)" "unprognostic (1.60e-1)" "unprognostic (8.60e-2)" "prognostic unfavorable (3.42e-4)" "unprognostic (2.59e-2)" "unprognostic (7.32e-2)" "unprognostic (5.63e-2)" "unprognostic (5.13e-3)" 2.0 73.0 88.3 1.3 121.0 0.0 2.3 139.7 82.9 2.0 143.8 5.2 0.4 2.8 5.7 0.3 4.1 0.2 11.8 72.3 130.9 11.2 0.1 1.0 0.3 121.3 121.0 0.6 0.9 8.9 30.3 0.4 117.8 1.9 1.1 60.5 43.4 0.4 0.8 10.3 1.6 1.2 124.7 0.1 10.7 1.0 147.5 0.5 0.1 0.5 1.2 0.8 1.1 137.2 0.4 1.9 3.9 0.3 0.6 0.5 0.0 0.2 1.4 8.6 2.6 0.0 1.1 0.0 0.4 0.1 368.0 0.1 0.3 1.2 4.3 0.0 0.1 0.0 12.4 0.0 1.4 0.0 0.1 2.6 9.3 6.5 149.7 409.5 0.0 0.0 0.0 0.3 2.3 0.1 0.0 0.0 2.5 0.2 14.0 0.1 1.6 0.0 14.6 0.0 30.3 2.5 0.8 0.1 0.8 0.4 0.1 0.0 0.0 252.2 0.0 8.5 39.7 0.0 0.0 0.0 149.6 0.0 10.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 88.3 121.0 139.7 82.9 72.3 130.9 121.3 121.0 117.8 124.7 147.5 137.2 0.1 0.0 0.0 68.9 0.0 0.4 5.9 1.9 1.8 123.3 1.6 0.6 12.2 0.0 1.4 3.7 14.6 0.0 0.0 0.0 1.9 0.2 7.3 4.1 1.5 0.6 28.7 0.0 24.1 1.3 0.2 4.3 0.0 6.7 0.0 1.6 0.0 0.0 0.1 11.8 333.0 0.0 6.1 0.0 0.8 1.9 5.9 0.9 19.6 8.4 0.1 52.0 0.0 435.8 247.7 0.3 0.0 6.0 0.0 4.5 0.0 1.2 34.1 55.0 0.0 0.1 0.8 1.2 1.1 0.5 0.0 0.1 0.2 0.6 0.1 0.5 DNMBP "ARHGEF36, KIAA1010, Tuba" ENSG00000107554 "Dynamin binding protein" Q6XZF7 10 99875577-100009947 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Cataract, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 75.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037878, HPA058216" Uncertain Approved "Nucleoli,Nuclear bodies,Golgi apparatus,Cytosol" Yes No "Cluster 15: NK-cells - Transcription" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 41: Macrophages - Immune response" "Nucleoli, Golgi apparatus, Cytosol" "Nuclear bodies" "HPA037878: AB_10675622, HPA058216: AB_2683640" "unprognostic (3.25e-1)" "unprognostic (8.19e-2)" "unprognostic (1.86e-1)" "prognostic favorable (4.95e-6)" "unprognostic (3.92e-2)" "unprognostic (4.13e-1)" "unprognostic (9.79e-2)" "unprognostic (4.07e-1)" "unprognostic (1.90e-1)" "unprognostic (1.02e-1)" "unprognostic (8.67e-3)" "unprognostic (4.03e-2)" "unprognostic (5.07e-3)" "unprognostic (6.52e-2)" "unprognostic (4.95e-2)" "unprognostic (1.28e-1)" "prognostic favorable (6.15e-4)" 13.6 6.0 3.6 5.5 3.7 10.3 10.2 6.2 5.3 15.8 8.6 17.7 22.5 9.6 12.5 10.2 11.3 11.0 7.5 4.7 4.2 20.6 13.1 8.4 4.6 3.7 3.6 11.5 17.6 31.7 3.9 10.5 3.8 8.9 20.7 15.8 8.4 12.8 13.4 27.4 27.2 8.8 3.0 7.7 23.8 6.9 5.2 20.1 8.1 11.1 5.2 19.8 17.7 3.1 25.7 20.7 18.4 29.2 32.9 27.4 4.4 45.2 43.6 21.5 20.7 14.2 38.0 26.6 18.9 34.9 11.8 19.9 21.6 26.1 29.9 1.4 6.7 3.8 23.7 10.0 17.1 2.6 1.8 13.0 5.7 26.6 23.4 75.5 52.1 8.5 3.6 0.0 44.1 3.2 4.5 5.1 17.7 18.0 12.3 5.5 18.7 1.4 36.6 21.9 3.1 4.2 7.4 1.9 5.7 25.3 1.5 2.4 63.4 16.0 15.3 13.1 29.8 2.1 1.7 36.3 15.2 8.4 12.2 0.0 0.8 0.2 0.7 1.2 0.7 1.2 0.1 0.4 0.3 1.9 0.1 0.3 0.7 2.1 1.2 0.3 0.0 0.6 3.6 3.7 6.2 5.3 4.7 4.2 3.7 3.6 3.8 3.0 5.2 3.1 6.8 9.6 11.0 11.1 14.8 35.1 7.2 5.0 5.2 6.3 9.3 6.3 6.1 12.8 11.2 12.9 35.5 7.7 4.4 36.7 3.9 7.5 1.0 27.0 11.0 12.6 3.6 0.0 15.9 14.3 1.4 17.6 26.0 43.9 2.5 4.1 11.4 12.8 4.7 13.5 24.8 25.0 6.1 10.7 9.6 3.2 13.7 20.5 3.6 23.4 3.3 4.3 0.0 10.6 2.6 19.3 23.6 9.1 6.1 4.0 36.5 3.7 19.9 26.6 0.0 4.3 6.9 4.2 9.3 9.0 45.6 3.7 4.3 15.0 28.4 21.8 DSC1 CDHF1 ENSG00000134765 "Desmocollin 1" Q08554 18 31129236-31162856 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skin 1: 228.8" "Cell type enriched" "Detected in some" 5 "Suprabasal keratinocytes: 166.5" "Group enriched" "Detected in some" 17 "head and neck cancer: 7.3;melanoma: 4.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "naive CD4 T-cell: 2.7;naive CD8 T-cell: 2.6" "Lineage enriched" "Detected in single" 8 "T-cells: 2.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA075379 Enhanced NA NA 27000000 "Cluster 32: T-cells - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 28: Keratinocytes - Keratinization" "HPA075379: AB_2732290" "unprognostic (1.41e-1)" "unprognostic (1.38e-1)" "unprognostic (2.12e-1)" "unprognostic (1.10e-1)" "unprognostic (6.95e-2)" "unprognostic (2.48e-2)" "unprognostic (3.71e-2)" "unprognostic (8.19e-3)" "unprognostic (1.56e-1)" "unprognostic (1.89e-1)" "unprognostic (1.27e-1)" "unprognostic (1.78e-1)" "unprognostic (5.65e-6)" "unprognostic (5.08e-2)" "unprognostic (2.91e-1)" "unprognostic (6.99e-2)" "unprognostic (4.74e-5)" 0.2 0.0 0.0 0.1 0.0 0.2 9.3 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.5 0.1 0.0 27.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.7 228.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 2.7 2.6 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 14.1 0.3 0.0 2.2 0.9 0.1 0.4 29.4 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.7 0.0 0.2 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.3 0.4 0.0 0.0 3.6 0.0 0.1 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.5 166.5 0.4 0.6 0.0 0.0 0.3 DSC3 "CDHF3, DSC, DSC1, DSC2, DSC4" ENSG00000134762 "Desmocollin 3" Q14574 18 30989365-31042815 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" Hypotrichosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 99.2;skin 1: 372.6" "Group enriched" "Detected in many" 5 "Basal keratinocytes: 500.7;Basal squamous epithelial cells: 214.5;Squamous epithelial cells: 419.6;Suprabasal keratinocytes: 688.8" "Cancer enhanced" "Detected in many" "cervical cancer: 78.6;head and neck cancer: 107.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 246.2;HBEC3-KT: 54.6;hTCEpi: 156.7;hTERT-HME1: 103.6;REH: 44.8" "Region enhanced" "Detected in some" "hippocampal formation: 3.3" "CAB037328, HPA049265, HPA073937" Enhanced Enhanced "Plasma membrane,Cell Junctions" NA NA 6000000 "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane, Cell Junctions" "CAB037328: , HPA049265: AB_2680695, HPA073937: AB_2686645" "unprognostic (4.44e-3)" "unprognostic (6.28e-2)" "unprognostic (1.46e-1)" "unprognostic (3.02e-3)" "unprognostic (2.38e-1)" "unprognostic (1.32e-2)" "unprognostic (6.38e-2)" "unprognostic (1.84e-2)" "unprognostic (2.41e-1)" "unprognostic (3.48e-2)" "unprognostic (3.92e-3)" "unprognostic (3.13e-1)" "unprognostic (4.13e-4)" "unprognostic (1.22e-2)" "unprognostic (7.85e-2)" "unprognostic (3.47e-1)" "prognostic unfavorable (1.04e-5)" 4.8 0.1 0.1 0.5 0.0 0.2 12.5 0.1 0.0 23.8 0.0 0.3 0.4 0.1 1.2 99.2 1.3 0.0 0.4 0.1 0.0 0.0 0.1 0.3 0.4 0.0 0.0 0.4 0.2 3.4 0.2 12.5 0.0 6.0 0.1 0.1 19.6 1.3 1.0 372.6 0.3 0.5 0.0 0.0 0.1 0.1 0.0 7.7 0.1 0.0 24.7 3.5 48.5 0.0 17.2 1.8 0.2 0.0 0.1 0.0 6.6 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.1 0.0 0.0 246.2 0.0 54.6 0.0 0.1 14.6 0.9 4.7 0.4 9.7 0.1 0.2 10.2 156.7 0.0 103.6 19.6 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.1 0.9 0.1 21.8 44.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.2 1.1 0.3 0.0 500.7 62.0 49.5 214.5 0.0 3.1 8.0 1.3 0.0 30.3 0.0 0.0 73.5 0.0 0.0 0.0 0.1 0.0 0.1 0.0 3.3 2.4 0.0 0.3 0.0 14.2 4.6 0.0 0.1 0.0 0.1 0.0 0.0 5.3 0.0 0.3 0.2 12.2 0.0 34.8 0.0 0.0 0.6 39.2 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 1.2 32.1 0.0 0.1 10.2 0.0 0.0 0.0 3.4 0.1 0.1 419.6 688.8 25.0 2.3 0.0 0.1 89.1 DSG1 "CDHF4, DSG" ENSG00000134760 "Desmoglein 1" Q02413 18 31318160-31359246 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Hypotrichosis, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "skin 1: 564.4" "Group enriched" "Detected in some" 25 "Basal keratinocytes: 117.4;Suprabasal keratinocytes: 315.7" "Group enriched" "Detected in many" 10 "head and neck cancer: 57.0;melanoma: 16.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 23 "hTCEpi: 6.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA022128, HPA074188" Enhanced NA NA 130000000 "Cluster 61: Skin - Cornification" "Cluster 30: Epithelial cell lines - Translation" "Cluster 28: Keratinocytes - Keratinization" "HPA022128: AB_1847620, HPA074188: " "unprognostic (2.55e-2)" "unprognostic (8.87e-2)" "unprognostic (2.00e-1)" "unprognostic (4.13e-1)" "unprognostic (5.22e-1)" "unprognostic (1.81e-2)" "unprognostic (1.57e-2)" "unprognostic (2.00e-2)" "unprognostic (1.51e-1)" "unprognostic (1.04e-2)" "unprognostic (2.19e-1)" "unprognostic (6.15e-2)" "unprognostic (4.24e-3)" "unprognostic (2.87e-1)" "unprognostic (1.44e-1)" "prognostic unfavorable (2.99e-4)" 0.4 0.0 0.0 0.0 0.0 0.2 24.7 0.0 0.0 17.6 0.0 0.0 0.0 0.0 0.0 18.4 0.0 0.1 1.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 13.6 0.0 2.0 564.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.6 0.0 0.0 2.1 0.0 30.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 117.4 0.0 0.0 0.6 0.0 3.3 0.9 1.7 1.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.1 0.1 0.0 0.0 8.6 3.5 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 4.9 0.2 6.5 315.7 0.0 0.2 0.0 0.1 0.0 DSP "DPI, DPII, KPPS2, PPKS2" ENSG00000096696 Desmoplakin P15924 6 7541617-7586714 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cardiomyopathy, Disease variant, Epidermolysis bullosa, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 460.7;skin 1: 854.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 902.0;Cardiomyocytes: 729.7;Squamous epithelial cells: 1657.5;Suprabasal keratinocytes: 2018.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 314.1" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 13 "naive B-cell: 2.0" "Lineage enriched" "Detected in single" 20 "B-cells: 2.0" "Cell line enhanced" "Detected in many" "BEWO: 278.0;HaCaT: 302.6;HBEC3-KT: 217.5;hTCEpi: 666.3;SuSa: 204.1" "Region enriched" "Detected in single" 23 "hippocampal formation: 11.6" "Region enhanced" "Detected in many" "spinal cord: 9.5" "CAB037324, HPA045840, HPA054950" Enhanced Supported "Cell Junctions" NA NA 100000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Cell Junctions" "CAB037324: , HPA045840: AB_2679468, HPA054950: AB_2682645" "unprognostic (1.65e-1)" "unprognostic (3.09e-1)" "unprognostic (6.13e-2)" "unprognostic (1.05e-2)" "unprognostic (1.09e-1)" "unprognostic (2.05e-2)" "unprognostic (3.82e-2)" "unprognostic (7.03e-3)" "unprognostic (1.28e-1)" "unprognostic (2.64e-2)" "unprognostic (5.02e-2)" "unprognostic (2.94e-2)" "prognostic favorable (1.53e-9)" "unprognostic (2.45e-1)" "unprognostic (2.88e-1)" "unprognostic (8.38e-2)" "prognostic unfavorable (1.82e-4)" 5.2 11.6 4.2 7.0 1.8 0.6 65.8 2.5 3.5 151.0 19.3 46.0 52.0 5.4 27.5 460.7 16.3 7.8 84.9 3.4 0.9 22.4 41.9 6.1 3.7 1.6 2.0 2.0 111.5 54.9 9.0 63.3 1.5 29.9 43.5 21.2 125.1 11.7 3.4 854.8 42.3 2.9 2.4 3.2 48.1 1.5 2.2 37.1 41.5 0.6 78.7 13.1 286.1 0.9 132.2 38.9 0.0 0.1 5.6 8.2 278.0 25.5 21.8 12.4 12.0 110.8 33.5 0.1 35.8 40.9 10.0 302.6 46.1 217.5 2.2 0.1 54.1 0.0 21.5 149.5 0.0 0.6 0.9 1.9 666.3 11.0 121.7 30.0 0.0 0.6 0.2 0.2 22.0 61.4 0.1 1.0 5.6 62.6 19.6 0.1 0.1 32.9 45.3 34.8 12.6 0.3 28.5 59.9 0.2 204.1 71.0 0.3 0.0 4.8 1.2 0.3 0.3 0.1 0.2 0.2 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 1.8 2.5 3.5 3.4 0.9 1.6 2.0 1.5 2.4 2.2 0.9 7.6 51.3 17.0 0.0 7.5 902.0 164.5 157.3 278.3 4.4 184.5 126.4 729.7 97.2 197.5 60.7 14.6 273.0 1.2 357.1 1.9 160.6 1.8 306.5 42.4 46.9 174.6 0.0 0.1 111.9 273.1 51.2 237.0 560.1 3.8 532.2 4.6 186.6 27.5 0.0 0.9 204.7 111.9 1.9 77.8 1.3 0.9 5.9 101.4 3.7 2.6 14.7 0.0 0.0 0.1 167.4 284.2 0.0 5.7 204.0 180.7 12.0 176.6 28.6 0.0 0.4 67.4 1.3 2.7 1657.5 2018.0 385.7 8.1 0.3 247.8 269.9 ECT2 ARHGEF31 ENSG00000114346 "Epithelial cell transforming 2" Q9H8V3 3 172750682-172821474 "Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Neurogenesis, Protein transport, Transport" "Guanine-nucleotide releasing factor" Oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 64.6;Spermatocytes: 42.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA036363, HPA053261" Enhanced Nucleoplasm,Cytosol No Yes "Cluster 1: Neutrophils - Mixed function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "HPA036363: AB_2732472, HPA053261: AB_2682094" "unprognostic (3.83e-2)" "unprognostic (4.34e-1)" "unprognostic (1.27e-2)" "unprognostic (4.22e-3)" "unprognostic (4.49e-2)" "unprognostic (5.02e-3)" "prognostic unfavorable (6.82e-6)" "prognostic unfavorable (1.13e-4)" "unprognostic (1.82e-2)" "unprognostic (1.01e-1)" "prognostic unfavorable (2.24e-5)" "unprognostic (2.44e-2)" "prognostic unfavorable (1.19e-5)" "unprognostic (1.08e-2)" "unprognostic (1.46e-1)" "unprognostic (1.29e-1)" "unprognostic (1.33e-1)" 3.6 3.3 2.1 8.2 1.9 19.8 7.5 3.4 3.4 8.1 1.4 11.5 9.3 4.4 1.8 8.9 3.3 5.3 3.2 2.4 1.4 4.3 2.6 5.2 10.5 2.1 1.7 1.3 2.9 3.6 1.2 8.8 2.7 3.2 15.8 12.5 5.6 2.6 2.1 7.1 7.6 7.5 0.7 4.3 9.4 15.9 2.3 23.3 3.9 2.7 11.4 6.9 4.2 3.5 192.0 133.6 103.2 54.0 10.6 21.8 51.6 81.5 67.5 121.4 116.9 74.7 196.9 47.2 122.1 48.8 116.0 81.8 84.2 53.1 164.3 67.8 46.6 29.6 70.0 38.5 4.6 46.2 32.8 7.1 9.0 72.2 73.2 34.0 53.0 68.6 31.3 67.2 97.2 67.6 47.5 34.6 84.4 156.7 72.0 33.7 101.1 60.7 92.2 43.7 68.6 44.1 104.5 117.4 42.2 51.5 195.4 34.1 46.5 58.5 55.7 79.6 174.9 32.8 47.2 88.2 51.6 39.7 78.0 6.0 2.0 0.7 1.0 1.7 1.1 1.4 1.4 0.9 1.6 1.3 0.6 0.9 6.3 0.7 0.7 1.6 2.5 0.7 2.1 1.9 3.4 3.4 2.4 1.4 2.1 1.7 2.7 0.7 2.3 3.5 6.7 6.4 3.2 4.2 3.8 19.5 4.9 6.2 9.1 3.4 10.1 6.5 3.6 5.7 5.7 3.7 64.6 12.0 2.9 10.7 0.0 9.5 3.3 20.1 6.6 7.7 4.8 25.2 6.5 9.2 14.9 6.0 17.9 20.5 0.0 17.9 5.3 2.9 7.3 0.0 2.5 13.5 10.2 4.7 6.3 2.8 0.9 5.1 7.2 15.0 2.8 3.1 2.1 3.0 4.9 20.7 3.8 1.5 9.6 12.8 1.5 3.7 11.0 16.3 0.0 2.9 5.2 42.6 30.4 16.9 12.8 3.8 4.1 3.3 13.5 8.8 EFNA3 "Ehk1-L, EPLG3, LERK3" ENSG00000143590 "Ephrin A3" P52797 1 155078837-155087538 "Predicted membrane proteins, RAS pathway related proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 30.9;skin 1: 102.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 63.2;Basal squamous epithelial cells: 44.3;Extravillous trophoblasts: 30.0;Squamous epithelial cells: 32.6;Suprabasal keratinocytes: 108.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "OE19: 46.3;SCLC-21H: 26.8;T-47d: 25.3" "Low region specificity" "Detected in all" CAB010494 Uncertain NA NA "Cluster 15: NK-cells - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 28: Keratinocytes - Keratinization" "CAB010494: AB_2097783" "unprognostic (3.75e-2)" "unprognostic (1.53e-2)" "unprognostic (1.56e-2)" "unprognostic (1.51e-2)" "unprognostic (3.88e-2)" "unprognostic (9.92e-2)" "prognostic unfavorable (2.46e-4)" "unprognostic (2.86e-2)" "unprognostic (3.56e-1)" "unprognostic (1.57e-1)" "unprognostic (5.14e-2)" "unprognostic (1.71e-1)" "prognostic unfavorable (9.66e-10)" "unprognostic (2.83e-3)" "unprognostic (6.38e-2)" "unprognostic (1.07e-1)" "unprognostic (1.90e-3)" 1.3 2.1 14.0 0.7 15.1 0.2 5.2 7.4 23.3 13.1 5.0 3.5 1.0 1.3 3.8 30.9 0.8 0.6 1.0 17.9 12.3 1.6 3.4 0.7 0.6 13.9 10.6 1.6 1.1 5.6 14.5 0.8 13.3 2.3 3.6 3.2 5.5 0.5 0.8 102.4 1.5 0.7 8.7 1.2 1.1 3.6 12.5 1.1 1.0 0.6 2.4 0.9 28.0 15.4 6.1 1.5 2.6 16.6 2.9 1.5 1.9 0.3 0.5 0.7 1.0 1.0 2.6 4.7 2.7 0.6 1.5 10.0 18.4 3.7 0.6 2.8 4.0 0.6 0.6 1.3 0.3 0.7 3.3 0.8 4.5 0.3 1.1 7.7 1.4 3.0 3.0 2.9 0.6 8.3 0.9 2.5 1.8 46.3 4.8 6.0 1.5 15.6 2.0 0.2 26.8 8.2 1.0 17.7 0.5 2.3 25.3 0.9 0.5 1.8 5.1 0.8 0.5 5.6 2.6 1.1 3.1 2.4 0.2 0.0 0.6 0.8 0.8 0.8 0.8 1.0 0.6 0.4 1.4 1.2 0.9 0.5 0.0 2.7 0.3 1.1 1.6 0.4 14.0 15.1 7.4 23.3 17.9 12.3 13.9 10.6 13.3 8.7 12.5 15.4 3.8 0.0 0.6 2.0 2.1 63.2 3.8 13.6 44.3 1.5 16.9 12.2 0.2 0.0 4.4 0.0 0.0 1.1 3.5 8.6 1.9 3.9 0.6 1.6 0.7 4.2 1.2 0.0 6.5 2.9 30.0 1.5 0.0 1.6 0.0 1.6 1.1 1.1 2.1 3.3 7.9 9.1 2.0 1.2 6.8 1.1 1.2 1.3 8.8 1.0 0.8 9.6 3.1 0.0 1.3 3.2 7.4 0.4 0.4 9.9 6.1 1.3 1.1 1.3 0.0 1.1 8.8 6.5 9.3 32.6 108.8 2.9 2.2 10.1 7.4 3.8 ELAPOR1 "EIG121, KIAA1324, maba1" ENSG00000116299 "Endosome-lysosome associated apoptosis and autophagy regulator 1" Q6UXG2 1 109113679-109206781 "Predicted intracellular proteins, Predicted membrane proteins" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 156.7;salivary gland: 166.1;stomach 1: 88.2" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.6;dendritic cells: 1.2;Hofbauer cells: 1.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 7 "neutrophil: 65.2" "Lineage enriched" "Detected in many" 7 "granulocytes: 65.2" "Cell line enhanced" "Detected in some" "MCF7: 20.8;SCLC-21H: 16.8;SK-BR-3: 17.6;T-47d: 59.1;U-87 MG: 12.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA029869, HPA070749" Enhanced Supported "Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 25: Pancreas - Digestion" "Cluster 6: T47d - Mammary gland" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "HPA029869: AB_10794320, HPA070749: AB_2686304" "unprognostic (2.10e-1)" "unprognostic (1.42e-2)" "unprognostic (1.99e-2)" "prognostic favorable (2.14e-7)" "unprognostic (4.18e-3)" "unprognostic (5.63e-2)" "unprognostic (1.96e-3)" "prognostic favorable (5.69e-5)" "unprognostic (2.79e-2)" "prognostic favorable (2.16e-4)" "unprognostic (3.50e-3)" "unprognostic (1.01e-1)" "unprognostic (2.22e-16)" "unprognostic (2.46e-1)" "unprognostic (1.75e-1)" "unprognostic (5.64e-2)" "unprognostic (8.02e-2)" 0.8 3.2 3.6 4.1 4.4 0.5 56.7 0.0 4.9 70.1 0.0 28.3 45.5 12.8 9.7 1.6 23.9 5.6 0.2 4.4 13.2 0.1 0.2 5.1 2.5 0.2 0.1 0.1 156.7 9.2 32.9 0.2 0.7 48.6 27.8 0.4 166.1 0.3 0.0 3.9 35.3 1.1 0.0 0.8 88.2 18.3 10.0 0.8 9.0 0.1 1.9 0.4 0.1 1.7 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.8 0.5 0.2 0.1 0.2 0.0 0.0 0.5 0.6 0.7 1.3 0.1 0.0 0.1 0.0 0.2 0.2 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 1.1 1.0 0.0 0.0 0.5 20.8 0.2 0.3 0.5 0.0 0.1 0.1 0.3 1.1 0.1 0.0 16.8 0.4 0.1 17.6 0.0 0.1 59.1 0.0 0.4 0.0 2.1 0.2 0.2 1.3 3.6 0.0 12.4 0.0 0.1 0.0 0.1 0.0 4.6 0.0 7.6 0.4 7.5 3.2 0.0 0.1 3.3 1.5 65.2 0.5 0.0 0.0 9.8 2.2 3.6 4.4 0.0 4.9 4.4 13.2 0.2 0.1 0.7 0.0 10.0 1.7 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.8 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.0 ELMO3 "CED-12, CED12, ELMO-3, FLJ13824" ENSG00000102890 "Engulfment and cell motility 3" Q96BJ8 16 67199111-67204029 "Predicted intracellular proteins" "Apoptosis, Phagocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 63.9;Paneth cells: 50.3;Proximal enterocytes: 100.3;Undifferentiated cells: 52.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 33.1;CAPAN-2: 49.3;HaCaT: 46.9;T-47d: 45.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA021484 Approved Approved "Plasma membrane,Cell Junctions" NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cell Junctions" "HPA021484: AB_1848129" "unprognostic (4.49e-3)" "unprognostic (2.04e-1)" "unprognostic (1.10e-2)" "unprognostic (8.08e-2)" "unprognostic (1.39e-1)" "unprognostic (6.16e-3)" "unprognostic (3.14e-1)" "unprognostic (8.17e-3)" "unprognostic (1.73e-1)" "unprognostic (8.06e-2)" "unprognostic (3.40e-2)" "unprognostic (6.95e-3)" "prognostic favorable (2.77e-5)" "unprognostic (3.47e-1)" "unprognostic (2.66e-1)" "unprognostic (1.84e-1)" "unprognostic (1.97e-2)" 2.8 1.8 1.5 4.3 1.4 5.6 8.8 2.4 2.6 6.4 0.3 24.3 33.1 2.0 4.1 25.8 8.5 8.6 1.9 1.1 1.7 21.4 8.1 8.3 2.9 2.1 1.0 1.8 41.0 8.5 29.8 7.1 2.8 19.3 9.1 0.7 20.3 9.6 1.2 33.5 26.3 0.8 0.4 5.6 26.0 13.0 1.3 2.1 19.3 0.3 2.6 8.5 13.2 1.5 22.1 2.5 2.4 3.0 0.4 0.6 33.1 1.3 0.7 1.6 1.4 14.2 49.3 3.0 1.5 0.7 0.7 46.9 2.2 21.6 0.3 1.4 2.9 3.2 4.8 4.7 1.0 1.9 7.5 0.5 15.6 1.2 1.1 1.6 1.7 2.6 3.1 1.5 0.9 18.4 2.0 9.3 3.2 20.7 1.9 4.6 2.3 4.9 2.0 2.9 16.2 3.6 3.2 14.4 1.5 1.3 45.8 3.4 2.8 3.7 4.5 2.3 2.3 4.9 1.7 5.8 1.9 4.4 1.8 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.1 0.1 0.0 1.5 1.4 2.4 2.6 1.1 1.7 2.1 1.0 2.8 0.4 1.3 1.5 1.8 0.0 13.1 0.0 2.0 8.8 11.9 21.9 13.1 0.9 20.6 16.3 1.2 15.7 12.6 20.2 0.0 33.8 1.0 63.9 17.6 20.1 22.9 8.8 1.7 1.6 13.1 6.9 0.4 24.0 15.0 1.7 47.4 12.2 4.5 1.3 1.4 3.6 3.6 0.0 0.3 33.8 22.4 1.6 3.1 36.3 0.9 2.6 3.6 1.9 2.8 0.4 0.0 0.0 1.0 24.8 50.3 0.7 1.4 7.9 100.3 28.6 12.3 1.5 0.0 0.4 1.6 14.5 5.9 14.4 13.5 16.8 2.3 5.0 52.3 13.0 ELMOD1 DKFZp547C176 ENSG00000110675 "ELMO domain containing 1" Q8N336 11 107591091-107666779 "Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 32.8;pituitary gland: 21.7;retina: 32.6;skin 1: 28.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 33.5;Excitatory neurons: 126.1;Horizontal cells: 37.0;Inhibitory neurons: 103.9;Oligodendrocyte precursor cells: 80.9" "Cancer enriched" "Detected in single" 15 "glioma: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HUVEC TERT2: 14.9;RH-30: 33.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038435, HPA066479" Uncertain Nucleoplasm,Cytosol NA NA "Cluster 11: Basophils - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm Cytosol "HPA038435: AB_10795575, HPA066479: " "unprognostic (2.74e-1)" "unprognostic (1.72e-4)" "unprognostic (2.58e-2)" "unprognostic (9.13e-2)" "unprognostic (3.93e-2)" "unprognostic (2.12e-2)" "unprognostic (1.34e-1)" "unprognostic (6.59e-3)" "unprognostic (1.93e-1)" "unprognostic (1.36e-1)" "unprognostic (6.29e-2)" "unprognostic (9.44e-2)" "unprognostic (1.34e-4)" "unprognostic (1.91e-2)" "unprognostic (3.15e-1)" "unprognostic (4.21e-2)" "unprognostic (1.39e-1)" 0.4 2.6 17.2 0.3 27.1 0.1 2.4 13.2 32.8 0.5 0.0 0.5 0.2 0.4 0.1 0.1 2.1 0.1 4.8 24.6 23.5 3.1 0.3 0.4 0.1 15.1 24.8 0.1 0.1 0.9 21.7 0.0 11.8 0.8 0.2 32.6 0.1 0.1 2.6 28.9 0.2 0.3 14.3 0.1 0.1 1.6 18.8 0.4 0.1 1.8 0.0 0.0 0.1 10.7 0.0 0.0 5.6 0.1 0.0 0.1 0.2 0.2 0.0 0.4 1.0 0.0 0.0 0.0 0.0 0.2 4.4 0.5 2.8 0.4 0.5 0.0 2.3 0.1 0.0 0.1 1.5 0.1 0.0 0.5 0.1 0.0 0.0 0.1 14.9 1.9 0.0 0.1 1.1 0.1 0.0 0.1 0.6 0.0 2.2 0.1 33.9 0.0 0.0 0.0 0.3 1.7 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.4 1.6 0.0 0.9 0.2 0.0 0.0 4.5 0.0 2.7 0.3 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.2 0.1 0.1 0.0 0.0 17.2 27.1 13.2 32.8 24.6 23.5 15.1 24.8 11.8 14.3 18.8 10.7 0.0 0.0 3.9 24.2 0.2 0.0 0.4 0.1 0.0 33.5 0.0 0.1 12.8 0.0 1.3 0.0 16.7 0.1 0.0 0.0 0.0 0.0 11.4 2.2 1.0 1.6 0.0 0.0 126.1 0.0 0.1 0.5 0.0 0.2 0.0 0.1 0.4 1.1 0.1 37.0 103.9 0.0 0.0 0.3 2.2 13.6 0.3 0.4 0.0 7.5 0.0 10.0 0.0 80.9 5.9 0.0 0.0 0.4 0.0 0.3 0.0 4.2 4.8 18.3 0.0 0.7 0.8 5.0 1.5 0.0 3.1 0.0 0.2 0.0 0.0 0.2 ELOVL1 Ssc1 ENSG00000066322 "ELOVL fatty acid elongase 1" Q9BW60 1 43363398-43368074 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Transferase "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033426, HPA056557" Enhanced Supported "Endoplasmic reticulum" NA Yes "Cluster 31: Non-specific - Inflammatory response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 30: Mammary glandular cells - Lactation" "Endoplasmic reticulum" "CAB033426: AB_2099896, HPA056557: AB_2683173" "unprognostic (5.23e-2)" "prognostic unfavorable (3.63e-5)" "unprognostic (8.00e-2)" "unprognostic (8.45e-2)" "unprognostic (7.60e-2)" "unprognostic (7.40e-2)" "prognostic unfavorable (2.79e-7)" "unprognostic (4.74e-2)" "unprognostic (1.33e-1)" "unprognostic (4.37e-1)" "prognostic unfavorable (8.51e-4)" "unprognostic (1.83e-1)" "unprognostic (2.88e-2)" "unprognostic (1.41e-2)" "unprognostic (1.28e-1)" "unprognostic (1.73e-1)" "unprognostic (9.00e-2)" 78.5 54.7 77.2 39.8 115.6 52.9 66.6 121.1 116.9 57.1 61.4 63.9 51.6 46.5 30.6 176.6 38.9 42.4 47.2 76.8 93.2 59.7 45.8 59.6 40.1 152.0 110.1 28.9 55.4 46.2 27.2 51.0 140.7 58.7 48.6 8.4 72.7 48.8 24.1 201.9 55.4 50.8 114.8 57.1 70.6 18.6 107.7 22.2 66.8 28.0 55.7 68.5 86.8 165.7 108.0 119.5 22.6 44.8 148.4 138.2 70.2 125.2 154.5 153.5 122.4 105.9 182.5 73.9 94.3 193.6 130.3 119.4 79.7 152.2 93.2 94.6 53.9 96.6 77.3 77.1 128.2 84.2 98.0 106.2 168.2 180.9 198.4 114.8 155.0 27.7 68.1 54.8 178.5 79.5 19.9 69.5 33.5 136.9 120.2 43.6 59.9 89.7 195.5 128.7 27.4 28.8 73.7 258.4 105.8 66.8 121.2 82.4 132.2 129.7 82.5 161.2 161.3 26.6 31.2 35.4 127.8 85.2 120.1 134.9 189.6 172.7 105.1 180.0 93.4 109.0 98.4 103.2 212.8 94.2 63.5 88.0 133.0 114.7 179.6 148.8 113.8 203.1 77.2 115.6 121.1 116.9 76.8 93.2 152.0 110.1 140.7 114.8 107.7 165.7 44.0 19.2 12.5 7.5 28.1 15.6 25.9 61.1 29.6 5.7 60.3 37.5 4.7 34.3 40.2 40.5 10.4 93.4 36.0 114.0 7.9 91.5 3.4 22.9 26.3 43.6 19.2 67.8 3.8 100.1 127.4 26.1 48.4 45.2 21.0 52.6 24.7 16.7 74.9 3.3 3.4 33.8 46.8 46.3 37.5 4.6 20.2 41.5 12.4 7.5 92.5 13.7 32.0 3.0 66.1 133.3 63.9 25.6 19.0 44.7 66.0 23.3 14.5 9.5 19.7 10.0 39.7 8.4 11.2 70.1 31.0 95.9 31.5 50.8 47.2 49.2 ELOVL3 CIG-30 ENSG00000119915 "ELOVL fatty acid elongase 3" Q9HB03 10 102226299-102229589 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "skin 1: 30.5" "Cell type enhanced" "Detected in some" "Adipocytes: 2.5;Breast myoepithelial cells: 3.2;Skeletal myocytes: 5.0;Spermatogonia: 3.4;Theca cells: 2.2" "Cancer enhanced" "Detected in many" "testis cancer: 10.6" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 10 "classical monocyte: 7.1;intermediate monocyte: 2.4;myeloid DC: 2.0;non-classical monocyte: 5.9" "Group enriched" "Detected in many" 10 "dendritic cells: 2.0;monocytes: 7.1" "Cell line enhanced" "Detected in many" "ASC diff: 9.5;ASC TERT1: 9.4;HSkMC: 13.9;NB-4: 11.6;SiHa: 22.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA036236 Enhanced Approved Vesicles,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 7: Non-specific - Mitochondria" "Vesicles, Cytosol" "HPA036236: AB_10601550" "unprognostic (1.52e-2)" "unprognostic (6.76e-2)" "unprognostic (1.84e-2)" "prognostic unfavorable (6.25e-5)" "unprognostic (8.23e-3)" "unprognostic (9.82e-2)" "unprognostic (2.17e-4)" "unprognostic (4.27e-2)" "unprognostic (2.28e-1)" "unprognostic (5.56e-2)" "unprognostic (1.84e-2)" "unprognostic (5.36e-3)" "unprognostic (2.66e-9)" "unprognostic (1.04e-1)" "unprognostic (2.81e-1)" "unprognostic (1.97e-1)" "unprognostic (1.79e-1)" 3.2 0.7 1.0 0.3 0.8 1.8 3.5 0.5 1.3 0.1 0.3 0.1 0.0 0.1 0.2 0.2 0.2 0.2 0.2 1.0 0.4 0.8 0.0 1.0 0.1 0.4 0.9 0.1 0.0 0.1 0.0 0.9 0.4 0.2 0.1 0.1 0.3 0.1 0.2 30.5 0.2 0.0 0.4 0.8 0.1 1.2 0.4 0.0 0.0 0.3 0.0 0.2 0.3 0.5 3.2 0.2 0.2 7.8 9.5 9.4 2.8 0.1 0.3 0.4 0.5 0.5 3.0 0.0 0.3 0.0 0.0 0.1 5.9 0.1 0.5 0.0 0.0 0.2 0.4 0.8 0.3 0.0 0.1 13.9 1.6 3.6 0.0 0.0 0.0 0.9 0.1 3.5 0.8 0.0 0.0 11.6 0.1 1.1 1.0 0.0 5.1 0.0 2.0 0.1 0.0 0.4 22.6 0.9 0.7 0.6 8.1 2.7 0.0 1.5 0.0 0.3 0.3 0.5 7.2 0.0 3.4 6.5 0.0 0.0 7.1 0.0 0.0 2.4 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.4 0.0 5.9 0.0 0.0 1.7 1.0 0.8 0.5 1.3 1.0 0.4 0.4 0.9 0.4 0.4 0.4 0.5 2.5 0.0 1.1 0.0 0.2 0.4 0.5 0.6 0.6 0.0 1.1 3.2 0.3 0.0 0.5 0.0 0.0 0.0 1.1 0.2 0.0 0.1 0.0 0.0 1.3 1.9 0.0 0.0 0.3 0.0 0.7 1.3 0.0 0.2 0.0 0.0 1.4 0.4 0.2 0.0 0.0 0.2 0.0 1.5 0.8 0.0 0.0 0.7 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 5.0 1.2 0.1 3.4 0.6 0.1 0.3 0.3 2.2 0.2 0.1 ELOVL5 "dJ483K16.1, HELO1, SCA38" ENSG00000012660 "ELOVL fatty acid elongase 5" Q9NYP7 6 53267398-53349179 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Transferase "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017042, HPA047752, HPA054197" Enhanced Enhanced "Endoplasmic reticulum" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 35: Glandular cells - Unknown function" "Endoplasmic reticulum" "CAB017042: , HPA047752: AB_2680147, HPA054197: AB_2682413" "unprognostic (7.33e-2)" "unprognostic (5.80e-2)" "unprognostic (1.04e-1)" "unprognostic (1.92e-2)" "unprognostic (1.16e-1)" "unprognostic (5.01e-2)" "unprognostic (3.06e-1)" "unprognostic (2.19e-1)" "unprognostic (4.38e-2)" "unprognostic (1.43e-2)" "unprognostic (3.23e-1)" "unprognostic (6.40e-2)" "prognostic unfavorable (1.94e-6)" "unprognostic (1.58e-1)" "unprognostic (5.12e-2)" "prognostic unfavorable (6.80e-4)" "unprognostic (2.76e-2)" 242.4 134.7 51.3 74.9 67.0 114.6 199.2 74.6 79.2 48.9 49.4 40.0 28.3 39.8 49.7 28.4 46.0 51.3 37.8 50.8 65.3 38.9 108.9 68.4 106.7 80.7 69.0 32.3 15.4 24.3 28.5 40.2 74.5 128.0 18.3 36.5 24.8 103.0 9.9 32.9 47.5 52.4 67.7 56.1 22.8 82.5 65.8 107.3 45.1 19.5 102.4 67.1 27.0 98.9 137.2 98.1 168.0 309.0 436.0 250.8 71.3 155.8 174.2 123.2 171.5 87.4 154.5 154.4 110.3 163.3 193.1 78.9 168.0 142.6 183.7 131.2 117.5 153.1 85.0 122.9 239.0 122.2 107.2 233.6 109.8 123.6 153.9 124.5 139.1 301.4 194.2 87.3 90.3 14.9 364.4 107.9 91.2 5.2 73.6 139.9 115.3 54.3 232.7 80.6 155.7 107.1 129.3 66.9 135.2 108.7 152.3 112.9 133.0 134.7 118.5 242.2 208.8 72.8 72.1 116.2 70.2 173.6 97.8 47.6 49.2 183.7 34.9 34.9 56.5 88.4 58.1 42.7 77.9 101.5 27.8 26.3 261.5 36.7 45.0 20.4 110.0 50.6 51.3 67.0 74.6 79.2 50.8 65.3 80.7 69.0 74.5 67.7 65.8 98.9 48.6 80.1 50.7 75.4 118.3 52.4 108.2 36.8 44.3 11.6 177.3 70.9 23.3 21.5 40.2 12.9 2.1 25.3 55.5 2.1 15.6 34.9 94.2 37.4 53.2 54.4 25.0 77.0 25.8 36.1 58.2 54.8 3.1 66.4 99.0 28.4 39.3 88.7 35.5 8.4 29.8 1.6 16.2 57.3 114.6 181.0 20.8 55.5 48.0 39.4 53.5 83.2 39.1 49.3 111.2 27.8 1.4 32.0 45.2 169.2 21.9 48.4 58.5 6.0 65.7 27.3 77.5 27.0 18.9 35.7 60.9 31.2 97.2 60.0 4.4 73.4 EMILIN3 "C20orf130, dJ620E11.4, EMILIN5" ENSG00000183798 "Elastin microfibril interfacer 3" Q9NT22 20 41359962-41366818 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "epididymis: 53.6" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 17.7;Granulosa cells: 7.6;Microglial cells: 4.7;Oligodendrocyte precursor cells: 3.5;Peritubular cells: 4.9;Skeletal myocytes: 3.2" "Group enriched" "Detected in many" 5 "glioma: 10.8;testis cancer: 2.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 6.3;HAP1: 11.1;NTERA-2: 7.0;SCLC-21H: 13.0" "Region enriched" "Detected in single" 30 "cerebellum: 3.3" "Region enriched" "Detected in single" 4 "spinal cord: 4.1" "HPA044034, HPA059912, HPA078559" Enhanced Approved "Golgi apparatus,Microtubules,Cytokinetic bridge" "Secreted to extracellular matrix" Yes NA 1200000 "Cluster 68: Epididymis - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 36: Stromal cells - Cell proliferation" "Golgi apparatus" "Microtubules, Cytokinetic bridge" "HPA044034: AB_2678783, HPA059912: AB_2684158, HPA078559: " "unprognostic (1.66e-4)" "unprognostic (1.85e-2)" "unprognostic (2.50e-2)" "unprognostic (2.14e-1)" "unprognostic (2.65e-1)" "unprognostic (2.15e-2)" "unprognostic (1.71e-1)" "unprognostic (7.66e-2)" "unprognostic (2.18e-3)" "unprognostic (2.57e-1)" "unprognostic (6.54e-2)" "unprognostic (7.66e-2)" "unprognostic (3.13e-7)" "unprognostic (2.64e-2)" "unprognostic (1.05e-1)" "unprognostic (1.97e-1)" "unprognostic (9.62e-2)" 0.6 1.4 2.5 0.1 2.4 0.0 3.5 2.3 3.8 8.6 1.8 4.9 0.6 2.3 53.6 0.8 4.2 0.3 7.8 2.1 2.2 1.0 0.6 0.3 0.1 3.7 2.7 8.9 0.2 0.1 1.8 0.0 3.0 6.7 0.3 0.0 1.0 9.9 0.9 3.9 1.7 0.9 2.5 0.1 2.0 1.7 2.6 0.5 0.3 2.6 0.2 2.3 4.7 3.0 0.0 0.1 6.3 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.3 0.0 0.0 0.1 0.0 0.4 0.0 11.1 0.0 0.2 0.0 1.3 0.0 0.0 0.4 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 13.0 1.3 0.0 0.0 0.0 2.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 2.4 2.3 3.8 2.1 2.2 3.7 2.7 3.0 2.5 2.6 3.0 0.6 0.0 0.0 0.7 0.0 0.9 0.2 0.0 0.0 0.3 1.2 2.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 17.7 0.4 0.0 0.0 1.1 0.0 0.0 0.8 0.0 0.7 0.0 7.6 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.3 1.8 0.1 0.0 4.7 0.0 0.1 0.0 3.5 0.1 0.0 1.2 4.9 0.0 0.2 0.3 0.1 0.0 0.0 0.0 3.2 0.6 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.2 0.1 EML2 "ELP70, EMAP-2, EMAP2" ENSG00000125746 "EMAP like 2" O95834 19 45606994-45645602 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 153.1;Syncytiotrophoblasts: 101.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012757 Approved Approved Vesicles NA NA 180000 "Cluster 27: Non-specific - Gene expression" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 30: Epithelial cell lines - Translation" "Cluster 46: Photoreceptor cells - Phototransduction" Vesicles "HPA012757: AB_1848145" "unprognostic (1.10e-1)" "unprognostic (1.36e-1)" "unprognostic (1.61e-3)" "unprognostic (2.12e-1)" "unprognostic (1.81e-3)" "unprognostic (1.13e-1)" "unprognostic (1.69e-2)" "unprognostic (1.16e-1)" "unprognostic (1.85e-1)" "unprognostic (3.05e-3)" "unprognostic (3.72e-1)" "unprognostic (2.75e-3)" "unprognostic (1.77e-1)" "unprognostic (2.85e-2)" "unprognostic (9.44e-2)" "unprognostic (7.48e-2)" "unprognostic (7.03e-2)" 11.2 32.7 23.2 13.6 41.7 14.1 12.9 43.2 37.6 16.4 9.7 21.3 11.5 9.1 6.8 40.2 12.0 10.9 20.4 19.5 36.1 17.5 7.9 13.6 13.4 57.6 35.4 5.2 21.1 55.1 14.3 19.8 52.8 15.8 14.4 49.0 29.0 18.3 5.7 38.6 11.9 7.1 27.9 12.9 18.9 3.5 40.3 16.5 20.9 4.9 12.5 19.5 24.9 57.9 47.6 16.2 3.2 1.1 25.0 13.6 17.4 29.2 37.0 12.6 14.8 6.2 39.5 14.6 17.0 15.4 4.0 39.7 6.0 57.4 4.0 56.7 15.0 5.7 19.5 12.4 47.1 18.5 13.4 21.1 74.5 15.1 74.1 10.5 9.4 28.0 18.3 38.5 10.0 49.9 10.3 4.2 1.9 75.7 14.3 2.3 5.6 18.9 33.3 61.2 17.8 3.3 16.4 32.0 22.1 17.0 18.7 18.9 15.1 0.0 5.4 4.8 0.3 66.2 43.9 7.9 20.4 20.9 38.7 7.8 3.7 5.7 6.5 4.8 5.1 5.5 4.4 6.7 4.4 2.2 2.9 3.9 1.0 2.6 5.2 6.4 5.8 3.9 23.2 41.7 43.2 37.6 19.5 36.1 57.6 35.4 52.8 27.9 40.3 57.9 10.6 3.2 13.1 8.5 15.7 18.6 42.9 40.3 27.3 32.2 13.2 14.2 9.0 14.3 25.5 35.0 14.6 66.4 24.5 34.1 37.2 16.8 72.1 28.6 9.0 13.8 17.5 5.5 29.7 20.8 20.4 7.6 38.7 20.1 19.1 6.7 20.3 6.4 15.8 28.6 46.0 32.6 26.4 8.8 9.6 27.0 4.1 8.7 19.6 5.6 13.1 16.4 12.3 15.1 68.0 17.9 29.1 7.2 25.0 23.7 11.0 7.5 40.7 153.1 0.0 6.8 16.4 3.5 6.1 29.6 14.3 101.0 23.2 39.1 31.9 41.9 EPPK1 EPIPL1 ENSG00000261150 "Epiplakin 1" P58107 8 143857324-143878467 "Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "skin 1: 16.1" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 137.1;Suprabasal keratinocytes: 274.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 14.3;EFO-21: 13.3;HaCaT: 13.8;HeLa: 26.8;MCF7: 20.2;SK-BR-3: 9.3" "Not detected" "Not detected" "HPA066808, HPA067357, HPA069333" Approved Enhanced "Intermediate filaments" NA NA 1200000 "Cluster 61: Skin - Cornification" "Cluster 20: HeLa - Mitochondria" "Cluster 28: Keratinocytes - Keratinization" "Intermediate filaments" "HPA066808: AB_2685726, HPA067357: AB_2685826, HPA069333: AB_2686123" "unprognostic (1.42e-1)" "unprognostic (9.30e-2)" "unprognostic (5.89e-2)" "prognostic unfavorable (5.52e-5)" "unprognostic (2.85e-2)" "unprognostic (5.86e-3)" "unprognostic (4.90e-2)" "unprognostic (8.73e-2)" "unprognostic (9.60e-2)" "unprognostic (2.31e-1)" "prognostic unfavorable (3.94e-4)" "unprognostic (1.35e-1)" "unprognostic (1.97e-3)" "unprognostic (5.94e-3)" "unprognostic (4.35e-1)" "unprognostic (3.68e-3)" "unprognostic (5.08e-3)" 0.2 0.0 0.4 0.3 0.4 0.1 0.9 3.9 0.5 0.5 1.3 3.3 2.1 2.4 0.3 1.7 2.0 0.2 0.1 0.8 0.6 1.2 0.3 0.9 0.1 2.5 2.7 0.0 0.7 0.2 0.2 0.2 1.7 1.4 0.6 0.0 2.2 1.4 0.2 16.1 2.7 0.9 1.6 1.2 2.1 1.8 0.7 0.1 0.2 0.0 0.2 1.8 0.9 0.4 7.9 0.1 0.1 0.0 0.0 0.0 14.3 0.0 0.0 0.0 0.0 7.4 0.5 0.0 13.3 0.0 0.0 13.8 1.4 0.1 0.0 0.0 3.4 0.0 26.8 4.6 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 20.2 0.0 0.0 1.4 1.8 0.0 0.0 0.1 0.0 0.0 4.9 2.3 0.0 2.2 9.3 0.0 1.2 7.5 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 3.9 0.5 0.8 0.6 2.5 2.7 1.7 1.6 0.7 0.4 0.7 19.2 9.2 1.0 1.1 137.1 20.3 8.2 8.0 0.6 32.7 25.0 27.9 11.5 4.4 14.7 0.0 2.5 0.0 48.1 0.0 11.3 0.5 12.6 0.5 3.2 6.0 0.0 0.3 14.7 0.3 2.4 12.2 10.1 0.0 0.6 0.7 4.4 0.3 0.0 0.0 14.5 12.2 0.0 8.2 0.3 0.0 0.4 16.0 0.0 0.0 0.6 0.0 0.0 0.1 31.9 21.7 0.0 0.2 8.6 28.2 7.0 24.2 0.2 0.0 0.0 5.2 1.5 1.0 10.6 274.3 6.2 1.2 0.1 28.4 31.5 ERBB4 "ALS19, HER4" ENSG00000178568 "Erb-b2 receptor tyrosine kinase 4" Q15303 2 211375717-212538841 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Lactation, Transcription, Transcription regulation" "Activator, Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Amyotrophic lateral sclerosis, Cancer-related genes, Disease variant, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.9;fallopian tube: 11.2" "Cell type enhanced" "Detected in many" "Astrocytes: 2020.2;Inhibitory neurons: 6091.7;Oligodendrocyte precursor cells: 2369.0;Oligodendrocytes: 1049.9" "Group enriched" "Detected in many" 4 "breast cancer: 4.1;endometrial cancer: 2.1;glioma: 1.2;ovarian cancer: 2.8;testis cancer: 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 6.9;EFO-21: 5.1;HEK 293: 3.8;RPTEC TERT1: 5.6;SCLC-21H: 3.1;T-47d: 5.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000276, HPA012016, CAB025522" Enhanced NA NA 220000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB000276: , CAB025522: , HPA012016: AB_1846541" "unprognostic (1.48e-1)" "unprognostic (3.28e-1)" "unprognostic (4.31e-3)" "unprognostic (1.76e-3)" "unprognostic (3.59e-1)" "unprognostic (2.75e-1)" "unprognostic (2.88e-1)" "unprognostic (9.56e-2)" "unprognostic (2.07e-1)" "unprognostic (4.67e-3)" "unprognostic (1.07e-1)" "unprognostic (3.61e-1)" "unprognostic (7.14e-3)" "unprognostic (1.49e-3)" "unprognostic (1.41e-1)" "unprognostic (1.14e-1)" "unprognostic (4.11e-2)" 0.3 0.4 10.0 0.0 13.3 0.0 5.6 10.5 11.5 2.9 0.0 0.1 0.0 0.2 0.0 0.1 11.2 0.0 3.0 9.9 12.7 5.1 0.0 0.8 0.0 4.9 16.9 0.1 0.6 3.1 2.4 0.1 7.6 0.3 0.0 2.0 4.7 1.2 1.5 0.3 0.0 0.0 4.3 0.0 0.4 3.3 8.0 0.0 1.6 1.7 0.0 0.1 0.1 6.1 0.0 0.0 6.9 0.2 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.0 0.0 0.0 5.1 0.7 0.0 0.3 0.2 0.0 0.0 0.1 3.8 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 2.1 0.0 0.0 0.3 0.0 5.6 0.3 3.1 0.2 0.0 0.1 0.1 0.1 5.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 13.3 10.5 11.5 9.9 12.7 4.9 16.9 7.6 4.3 8.0 6.1 0.4 0.0 12.6 2020.2 0.0 0.6 0.9 1.1 0.6 15.9 45.6 17.0 27.2 0.0 10.2 12.9 0.0 0.0 0.2 0.0 5.9 0.5 6.7 25.4 1.0 1.0 0.0 0.0 62.0 0.5 0.2 1.8 0.0 25.8 0.0 5.4 0.0 0.0 0.1 0.0 6091.7 0.0 2.0 0.0 0.3 2.2 1.8 0.3 3.6 96.5 0.0 9.1 0.0 2369.0 1049.9 0.0 0.0 0.4 0.0 1.6 0.0 0.2 28.1 1.9 6.6 4.1 3.0 1.8 2.6 0.2 1.3 0.0 0.2 0.0 0.0 1.2 ERCC6L "FLJ20105, PICH, RAD26L" ENSG00000186871 "ERCC excision repair 6 like, spindle assembly checkpoint helicase" Q2NKX8 X 72204657-72239027 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 3.2;lymphoid tissue: 3.6" "Cell type enhanced" "Detected in some" "Erythroid cells: 3.4;Granulosa cells: 2.5;Spermatocytes: 2.1;Spermatogonia: 2.4;Squamous epithelial cells: 2.4" "Cancer enhanced" "Detected in many" "testis cancer: 11.0" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 4 "NK-cell: 1.7" "Lineage enriched" "Detected in single" 4 "NK-cells: 1.7" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA050492 Approved Uncertain Nucleoplasm,Centrosome,Cytosol No Yes "Cluster 15: NK-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Centrosome "Nucleoplasm, Cytosol" "HPA050492: AB_2681145" "prognostic unfavorable (1.80e-4)" "unprognostic (2.93e-1)" "unprognostic (1.95e-2)" "unprognostic (5.76e-3)" "unprognostic (2.43e-1)" "unprognostic (2.36e-1)" "unprognostic (9.23e-6)" "unprognostic (8.63e-3)" "unprognostic (1.57e-2)" "unprognostic (1.99e-2)" "unprognostic (3.68e-5)" "unprognostic (4.61e-2)" "unprognostic (0.00e+0)" "unprognostic (2.97e-3)" "unprognostic (9.56e-2)" "unprognostic (1.17e-1)" "unprognostic (6.41e-2)" 0.1 0.1 0.1 1.3 0.2 3.2 0.4 0.8 0.2 0.4 0.1 0.9 0.7 0.2 0.2 1.1 0.2 0.2 0.1 0.1 0.0 0.1 0.1 0.1 2.3 0.1 0.0 0.3 0.1 0.0 0.1 0.5 0.1 0.1 1.1 0.5 0.3 0.0 0.1 0.6 0.6 0.3 0.0 0.5 0.7 0.8 0.2 3.6 0.1 0.0 2.7 0.2 0.4 0.6 19.0 16.3 14.6 9.3 1.0 1.7 8.0 19.8 9.1 17.0 17.7 13.3 11.6 30.5 7.3 7.2 23.0 15.2 27.8 14.8 30.1 17.5 20.2 10.5 5.5 7.9 0.0 20.7 14.2 0.2 0.9 23.7 4.4 2.8 9.6 15.1 14.1 7.3 17.6 14.8 19.8 12.1 26.6 18.3 24.8 16.4 26.2 5.4 4.4 11.5 12.0 8.6 14.7 9.8 3.6 11.8 7.5 4.6 6.0 11.4 18.3 21.8 13.1 5.7 9.4 25.9 8.1 14.1 11.7 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.1 0.4 0.1 1.7 0.1 0.1 0.4 0.1 0.1 0.2 0.8 0.2 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.6 0.1 0.0 0.0 0.0 0.9 0.3 0.2 0.5 0.0 0.0 0.3 0.6 0.5 1.5 0.2 0.0 0.0 1.1 0.9 0.6 0.0 0.0 0.3 0.9 0.8 0.3 0.0 3.4 0.9 0.0 1.7 0.5 0.0 0.5 0.0 2.5 0.0 0.0 1.0 0.0 0.7 0.4 0.0 0.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.5 1.7 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.4 2.1 2.4 2.4 0.1 0.4 0.3 0.2 0.9 0.1 EREG ER ENSG00000124882 Epiregulin O14944 4 74365145-74388749 "Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Mitogen" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "bone marrow: 129.0" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 179.1;Kupffer cells: 133.9;Langerhans cells: 171.1;Macrophages: 570.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 11.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 270.0;CAPAN-2: 76.7;hTEC/SVTERT24-B: 83.7;U-2197: 181.4;U-87 MG: 307.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA054373 Approved Vesicles "Secreted to blood" NA NA 46000 "Cluster 67: Neutrophils - Humoral immune response" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 41: Macrophages - Immune response" Vesicles "HPA054373: " "unprognostic (1.26e-2)" "prognostic unfavorable (1.67e-7)" "unprognostic (4.56e-3)" "unprognostic (3.94e-2)" "unprognostic (2.24e-3)" "unprognostic (1.00e-1)" "unprognostic (1.06e-2)" "prognostic unfavorable (1.45e-5)" "unprognostic (1.07e-1)" "unprognostic (7.34e-2)" "prognostic unfavorable (6.57e-5)" "unprognostic (2.94e-1)" "unprognostic (1.70e-6)" "unprognostic (2.42e-2)" "unprognostic (1.13e-2)" "unprognostic (6.59e-3)" "unprognostic (3.16e-3)" 4.5 0.0 0.3 10.3 0.3 129.0 2.5 0.2 0.5 1.9 0.2 2.0 0.2 0.2 0.2 12.6 0.8 5.7 0.7 0.3 0.1 0.1 0.2 2.7 0.1 0.2 0.1 0.1 0.3 0.0 0.0 0.6 0.4 0.1 3.4 0.1 1.3 0.0 0.2 9.3 1.6 3.0 0.0 0.5 0.2 0.1 0.6 0.1 0.1 0.0 1.0 4.9 4.0 0.3 1.4 41.1 0.0 0.0 3.8 6.6 0.1 9.2 270.0 2.6 1.6 32.5 76.7 0.0 44.1 0.0 20.1 2.4 0.0 59.3 2.7 0.0 0.0 1.2 1.6 1.2 1.1 0.1 0.1 3.9 20.2 83.7 43.5 0.0 0.0 0.0 0.1 0.5 0.2 0.4 0.1 0.1 0.1 0.2 0.6 0.1 0.0 0.1 0.6 1.6 0.0 0.0 27.0 0.2 0.0 0.0 0.1 0.0 0.0 1.6 0.6 181.4 0.0 0.0 0.0 0.2 307.0 0.0 0.2 0.4 0.2 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.2 0.5 0.3 0.1 0.2 0.1 0.4 0.0 0.6 0.3 4.9 6.4 7.2 0.0 5.7 5.4 5.6 179.1 4.0 0.0 24.4 2.3 18.2 5.7 82.4 0.0 0.0 0.4 2.2 56.3 0.0 1.8 3.7 2.4 0.7 2.5 3.6 17.0 0.1 0.2 0.7 4.4 0.5 3.9 7.0 0.1 0.4 1.9 26.8 0.0 1.8 38.2 16.2 133.9 171.1 1.0 0.3 570.7 7.2 0.0 23.2 0.0 0.0 0.0 0.0 0.8 27.1 0.0 11.7 2.5 32.4 0.2 41.9 0.0 0.0 2.5 3.1 0.5 0.3 3.8 9.2 0.7 3.3 0.2 33.1 7.4 ESPN DFNB36 ENSG00000187017 Espin B1AK53 1 6424776-6461367 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Hearing Actin-binding "Deafness, Disease variant, Non-syndromic deafness, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 129.1;retina: 117.8;testis: 145.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 175.5;Early spermatids: 137.5;Late spermatids: 461.6;Muller glia cells: 272.5;Paneth cells: 186.3;Proximal enterocytes: 512.1" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 6 "cerebellum: 13.4;thalamus: 6.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 48.9;Hep G2: 81.5;SK-BR-3: 160.1;T-47d: 53.6" "Low region specificity" "Detected in some" "Region enhanced" "Detected in some" "cerebellum: 2.6" "HPA028674, HPA060220" Enhanced Approved Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 45: Enterocytes - Digestion" Vesicles "HPA028674: AB_10601316, HPA060220: AB_2684224" "unprognostic (5.06e-2)" "unprognostic (1.18e-2)" "unprognostic (2.69e-1)" "unprognostic (1.28e-1)" "unprognostic (2.19e-2)" "unprognostic (1.41e-1)" "unprognostic (1.59e-1)" "unprognostic (2.28e-1)" "unprognostic (1.16e-1)" "unprognostic (5.71e-2)" "unprognostic (7.48e-3)" "unprognostic (5.53e-2)" "unprognostic (6.26e-3)" "unprognostic (5.51e-2)" "unprognostic (1.16e-1)" "unprognostic (3.04e-2)" "unprognostic (1.17e-2)" 0.6 5.7 0.4 2.6 1.0 28.0 9.2 13.4 1.0 30.3 0.2 28.2 90.4 2.4 39.9 34.3 18.6 0.3 0.9 0.4 1.7 63.4 129.1 3.2 0.3 0.6 1.3 0.4 0.9 26.8 42.1 0.9 1.1 10.0 6.8 117.8 9.4 6.2 0.8 91.7 89.5 0.8 0.3 0.9 2.7 145.3 6.1 1.6 0.4 0.0 1.7 1.3 22.3 0.5 14.1 0.7 0.6 0.1 0.0 0.0 48.9 0.0 0.0 0.2 0.0 29.9 1.5 0.5 6.5 0.0 0.1 32.6 2.3 0.1 0.0 2.0 0.7 0.4 0.7 81.5 0.0 0.6 2.7 0.1 0.6 0.0 0.0 0.0 0.0 1.0 17.6 0.0 0.0 28.2 0.2 1.0 0.6 3.8 12.2 0.0 0.4 10.9 0.2 0.1 21.0 0.7 3.7 160.1 5.0 0.3 53.6 7.4 15.6 0.1 0.8 0.6 0.0 0.0 0.2 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.4 1.0 13.4 1.0 0.4 1.7 0.6 1.3 1.1 0.3 6.1 0.5 0.2 0.0 0.6 0.0 0.8 7.8 2.4 4.5 12.5 5.6 10.7 3.9 1.4 11.5 3.8 9.2 68.8 3.0 0.2 175.5 13.7 0.2 137.5 19.1 0.9 0.8 6.0 8.2 0.2 3.1 0.5 0.3 5.6 12.4 0.0 0.0 3.9 109.4 0.2 0.0 0.2 36.3 8.2 3.2 0.9 461.6 3.7 1.5 0.0 0.0 0.0 272.5 0.0 0.0 0.1 0.1 186.3 2.2 0.0 1.6 512.1 102.2 9.0 72.5 0.0 0.0 0.2 12.3 3.9 17.6 22.7 6.6 1.5 0.0 35.3 2.9 ESRP1 "FLJ20171, RBM35A" ENSG00000104413 "Epithelial splicing regulatory protein 1" Q6NXG1 8 94641074-94707466 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Intestinal goblet cells: 107.2;Suprabasal keratinocytes: 79.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 138.3;BEWO: 101.1;CAPAN-2: 140.8;hTCEpi: 226.5;OE19: 142.6;RT4: 99.1;T-47d: 108.0" "Not detected" "Not detected" "Not detected" "Not detected" "HPA023719, HPA023720, HPA067104" Enhanced Enhanced "Nucleoplasm,Nuclear bodies" "Intracellular and membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 27: Mucus-secreting cells - Mucin production" "Nuclear bodies" Nucleoplasm "HPA023719: AB_1856124, HPA023720: AB_1856125, HPA067104: AB_2685779" "prognostic unfavorable (9.28e-4)" "unprognostic (7.12e-2)" "unprognostic (2.75e-2)" "prognostic unfavorable (3.56e-4)" "unprognostic (4.12e-1)" "unprognostic (6.99e-3)" "unprognostic (2.70e-1)" "unprognostic (2.61e-2)" "unprognostic (5.19e-2)" "unprognostic (5.51e-2)" "prognostic unfavorable (2.05e-4)" "unprognostic (4.48e-2)" "prognostic favorable (1.96e-8)" "unprognostic (1.34e-1)" "unprognostic (2.63e-1)" "unprognostic (4.96e-2)" "unprognostic (1.29e-1)" 0.2 0.0 0.0 5.2 0.0 0.0 24.2 0.0 0.0 15.5 0.0 57.1 25.2 3.4 29.6 64.2 21.3 8.5 0.1 0.0 0.0 8.5 0.4 15.8 0.0 0.0 0.1 0.1 42.6 28.4 7.2 12.2 0.0 19.9 62.8 0.0 25.9 10.0 0.1 60.6 22.0 2.5 0.0 0.0 38.6 0.6 0.4 5.2 36.6 0.0 15.3 22.5 28.8 0.0 138.3 0.0 0.0 0.2 0.0 0.0 101.1 0.0 0.0 0.0 0.0 44.6 140.8 0.0 3.8 0.0 0.1 81.6 3.8 70.9 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.1 0.0 226.5 0.0 1.4 0.0 0.0 10.7 0.0 0.0 0.0 67.3 1.9 0.4 12.4 142.6 3.4 0.0 0.0 18.3 17.4 99.1 35.1 0.3 0.0 21.0 14.0 21.4 108.0 0.9 0.0 0.1 0.2 0.1 0.3 12.0 13.8 0.3 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.2 38.5 36.7 0.0 0.6 44.6 18.9 30.4 35.9 0.0 29.4 18.0 1.0 21.5 32.4 27.6 0.0 55.1 0.5 76.2 13.7 19.6 12.9 47.1 3.7 0.9 33.1 0.0 2.6 27.5 69.1 0.9 58.1 46.5 1.3 0.0 0.4 0.1 6.0 0.0 0.4 107.2 16.2 0.0 3.2 10.3 0.0 0.5 24.9 0.0 0.6 0.0 0.0 0.5 0.4 21.7 48.1 0.7 1.8 25.1 25.5 0.3 35.0 0.0 0.0 0.0 1.2 0.6 0.9 71.3 79.1 62.1 0.8 0.0 73.9 40.1 ESYT3 "CHR3SYT, FAM62C" ENSG00000158220 "Extended synaptotagmin 3" A0FGR9 3 138434586-138481686 "Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.1;skin 1: 7.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 38.5;Alveolar cells type 2: 37.7;Excitatory neurons: 9.4;Inhibitory neurons: 9.7" "Cancer enhanced" "Detected in some" "thyroid cancer: 2.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "JURKAT: 1.4;NTERA-2: 3.3;SCLC-21H: 3.5;SK-MEL-30: 1.7;SuSa: 1.4" "Region enhanced" "Detected in many" "hypothalamus: 7.3" "Low region specificity" "Detected in all" HPA039200 Approved NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 11: Alveolar cells - Smell perception" "HPA039200: AB_10805356" "unprognostic (4.48e-2)" "unprognostic (3.07e-2)" "unprognostic (1.21e-2)" "unprognostic (1.38e-4)" "unprognostic (2.23e-1)" "unprognostic (8.22e-2)" "unprognostic (3.55e-3)" "prognostic favorable (8.30e-4)" "unprognostic (3.38e-1)" "unprognostic (5.57e-2)" "unprognostic (6.19e-3)" "unprognostic (4.88e-3)" "unprognostic (3.16e-5)" "unprognostic (3.46e-1)" "unprognostic (1.12e-1)" "unprognostic (2.13e-1)" "unprognostic (6.43e-2)" 0.1 0.1 2.5 0.0 2.0 0.0 0.7 5.1 2.2 0.8 0.2 3.8 0.0 2.2 0.0 0.4 0.2 0.3 0.5 2.1 2.3 0.9 0.0 4.7 0.0 2.2 2.1 0.5 1.0 0.8 1.9 0.3 2.5 0.2 0.2 0.1 0.3 0.0 0.4 7.7 0.3 1.5 1.3 0.0 1.7 0.5 2.4 0.0 4.7 0.0 0.4 1.0 0.7 1.5 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.5 0.1 0.0 0.8 0.8 0.1 0.2 1.3 0.0 0.0 0.2 0.0 0.1 0.4 0.5 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.1 0.2 3.3 0.0 0.2 0.0 0.0 0.0 0.3 0.0 3.5 0.0 1.2 0.1 1.7 1.4 0.3 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 2.0 5.1 2.2 2.1 2.3 2.2 2.1 2.5 1.3 2.4 1.5 0.1 38.5 37.7 4.2 0.1 0.8 0.8 0.5 1.2 1.9 0.9 1.3 2.5 1.5 4.5 1.8 4.2 0.8 0.0 0.1 0.0 1.0 0.2 1.5 0.8 0.7 0.0 0.0 9.4 0.9 0.4 0.9 3.6 2.2 0.0 0.5 0.4 0.1 0.2 0.0 9.7 0.0 0.0 0.0 0.4 0.2 0.3 0.2 1.8 1.0 0.0 0.3 0.0 2.0 0.5 0.7 0.1 0.0 0.0 1.1 0.0 0.3 0.8 3.9 0.0 1.4 0.3 1.5 1.7 0.5 1.6 0.7 0.1 0.7 0.2 0.1 ETV3 PE-1 ENSG00000117036 "ETS variant transcription factor 3" P41162 1 157121191-157138474 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 361.2;monocytes: 97.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004794, HPA073211" Supported Approved Nucleoplasm,Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 44: HDLM-2 - Immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm Vesicles "HPA004794: AB_1078761, HPA073211: " "unprognostic (1.65e-1)" "unprognostic (2.37e-1)" "unprognostic (3.78e-2)" "unprognostic (4.39e-2)" "unprognostic (7.59e-2)" "unprognostic (5.23e-2)" "unprognostic (1.38e-2)" "unprognostic (3.30e-1)" "unprognostic (2.36e-2)" "unprognostic (5.37e-2)" "unprognostic (1.34e-2)" "unprognostic (8.02e-2)" "unprognostic (7.26e-3)" "unprognostic (1.18e-1)" "unprognostic (1.22e-1)" "unprognostic (8.97e-2)" "unprognostic (6.65e-2)" 13.7 7.7 6.6 11.1 6.6 24.0 12.1 7.9 20.1 8.3 5.3 8.7 15.1 9.3 7.5 15.6 7.8 12.7 7.4 8.3 8.1 6.6 6.6 12.6 10.1 7.7 6.5 11.5 6.4 23.9 5.0 12.8 7.0 10.2 9.5 5.7 9.2 8.5 9.4 31.5 14.6 10.1 7.1 10.0 10.0 9.4 7.4 10.8 7.9 8.8 12.5 17.6 11.4 7.1 11.9 11.4 11.6 10.1 17.3 11.3 9.9 10.9 11.4 10.5 9.7 12.2 11.6 14.2 13.4 13.4 5.6 18.0 12.8 16.7 13.8 31.0 8.1 11.9 12.2 6.7 10.3 19.0 18.1 12.5 19.2 15.7 13.3 8.5 11.1 8.8 13.9 10.2 12.0 15.7 5.8 10.7 38.6 16.9 8.7 8.7 13.8 16.3 8.1 43.9 9.8 19.0 11.9 28.1 29.5 20.7 14.4 20.7 18.8 13.5 11.9 13.2 13.7 24.6 13.5 16.7 15.5 10.9 45.2 6.3 4.6 3.3 4.5 4.2 6.2 2.1 3.9 4.5 4.5 2.4 3.9 3.5 5.4 4.2 4.2 1.2 3.3 2.6 6.6 6.6 7.9 20.1 8.3 8.1 7.7 6.5 7.0 7.1 7.4 7.1 22.9 35.3 16.2 3.6 20.4 70.4 18.4 20.2 71.7 2.3 18.2 14.4 9.4 5.7 24.3 12.9 10.4 7.5 37.2 22.1 0.0 6.4 9.4 18.1 18.0 19.4 10.7 5.9 8.1 6.3 9.0 16.3 15.3 29.5 22.2 6.4 15.4 8.3 8.7 1.7 6.9 12.5 10.2 13.2 361.2 7.3 4.1 69.0 16.0 5.6 97.0 3.9 10.3 6.0 4.4 10.4 13.4 4.5 25.3 16.5 16.0 3.2 29.7 6.3 13.1 16.4 15.4 10.2 9.4 64.2 78.7 14.9 40.4 6.0 14.4 51.4 EXOC1L ENSG00000250821 "Exocyst complex component 1 like" A0A1B0GW35 4 55819790-55837489 "Predicted intracellular proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 8 "Theca cells: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 20 "NK-cell: 1.9" "Lineage enriched" "Detected in single" 20 "NK-cells: 1.9" "Cell line enhanced" "Detected in single" "HEK 293: 1.5" "Region enriched" "Detected in single" 4 "pons and medulla: 2.8" "Not detected" "Not detected" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.3 0.2 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.5 0.0 0.0 EXOC6B "KIAA0919, SEC15B, SEC15L2" ENSG00000144036 "Exocyst complex component 6B" Q9Y2D4 2 72175984-72826041 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Exocytosis, Protein transport, Transport" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 50.7" "Cell type enhanced" "Detected in many" "Astrocytes: 210.3;Excitatory neurons: 351.1;Inhibitory neurons: 393.6;Microglial cells: 286.7;Oligodendrocyte precursor cells: 288.5;Oligodendrocytes: 863.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034546, HPA063991" Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 15: RT4 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Nuclear bodies" Cytosol "HPA034546: AB_2674218, HPA063991: AB_2685168" "unprognostic (5.29e-2)" "unprognostic (1.40e-1)" "unprognostic (1.92e-1)" "unprognostic (1.18e-3)" "unprognostic (1.81e-1)" "unprognostic (7.56e-2)" "unprognostic (1.06e-2)" "unprognostic (9.34e-2)" "unprognostic (1.32e-1)" "unprognostic (2.16e-3)" "unprognostic (3.38e-2)" "unprognostic (2.61e-1)" "unprognostic (4.35e-3)" "unprognostic (4.38e-3)" "unprognostic (1.55e-1)" "unprognostic (1.18e-1)" "unprognostic (5.29e-2)" 11.3 13.4 22.3 4.2 32.7 1.2 8.6 18.8 23.9 12.6 3.2 8.6 7.3 10.1 6.0 15.1 7.8 6.5 50.7 20.7 25.7 7.2 3.8 7.2 3.1 23.9 25.7 15.0 5.0 13.2 6.1 13.0 23.3 8.0 5.7 14.1 7.7 8.9 11.1 26.5 9.1 10.0 16.4 5.2 6.9 6.9 22.2 4.4 10.2 11.5 6.4 9.7 13.0 40.9 21.7 16.3 14.7 17.8 41.2 16.9 25.3 15.6 21.9 13.2 8.6 22.3 3.3 5.6 9.5 26.2 19.6 35.4 12.4 25.7 18.9 4.2 10.1 16.7 11.0 12.8 22.2 2.4 5.5 14.6 36.6 14.9 23.1 20.6 21.8 8.7 1.8 0.0 17.6 7.5 6.4 2.9 15.3 14.9 9.0 3.4 26.4 2.3 12.7 50.1 7.3 6.3 26.7 8.2 10.9 16.1 5.7 2.3 24.3 15.2 12.8 13.1 9.6 5.5 5.9 0.0 17.7 1.2 12.4 1.3 0.5 0.0 0.7 0.4 0.5 0.7 0.5 0.4 0.4 0.7 0.6 0.9 0.0 0.5 0.6 0.1 0.8 0.4 22.3 32.7 18.8 23.9 20.7 25.7 23.9 25.7 23.3 16.4 22.2 40.9 17.8 0.0 4.1 210.3 4.1 26.1 10.2 9.8 14.8 17.4 5.2 5.2 87.1 12.8 5.1 9.2 25.0 15.1 5.0 10.2 5.9 9.3 62.9 5.6 14.5 14.1 3.0 2.1 351.1 11.5 13.2 12.4 30.5 9.2 8.2 11.6 11.4 5.6 4.6 16.8 393.6 6.0 4.1 12.0 7.1 8.2 8.4 5.0 5.4 286.7 2.0 9.9 1.0 288.5 863.3 11.0 8.6 7.5 3.7 8.1 28.2 5.5 8.4 11.1 0.0 13.5 14.7 12.0 4.9 13.1 37.4 24.6 4.7 5.5 4.5 10.7 EXOSC7 "EAP1, hRrp42p, KIAA0116, p8, RRP42, Rrp42p" ENSG00000075914 "Exosome component 7" Q15024 3 44975241-45036066 "Predicted intracellular proteins" "rRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036182, HPA057980" Approved Supported "Nuclear speckles" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Translation" "Cluster 24: NB-4 - Immune response" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles" "HPA036182: AB_10673346, HPA057980: AB_2683571" "unprognostic (1.69e-2)" "unprognostic (3.92e-3)" "unprognostic (1.84e-3)" "unprognostic (4.97e-2)" "unprognostic (3.00e-3)" "unprognostic (2.16e-1)" "unprognostic (2.34e-3)" "unprognostic (2.21e-2)" "unprognostic (2.96e-1)" "unprognostic (7.85e-2)" "unprognostic (1.20e-1)" "unprognostic (7.67e-3)" "prognostic favorable (2.69e-4)" "unprognostic (4.33e-1)" "unprognostic (7.30e-2)" "unprognostic (2.94e-1)" "unprognostic (1.20e-1)" 17.5 44.1 9.5 12.5 9.5 17.2 18.4 10.0 10.4 23.5 10.7 15.3 11.6 20.4 7.0 27.2 17.0 9.1 27.0 9.5 10.9 22.2 18.1 15.0 19.6 10.4 9.8 19.0 18.6 20.1 17.3 15.4 10.1 15.9 10.8 5.9 17.5 15.9 43.8 44.6 13.2 11.2 9.7 15.3 20.0 23.2 10.5 20.2 19.9 36.4 16.8 22.7 22.2 9.8 61.5 55.7 44.9 37.3 45.9 50.0 40.5 26.2 42.2 56.0 57.7 93.3 47.8 77.4 40.3 45.6 42.6 33.9 55.9 72.2 46.0 52.3 49.2 67.5 64.5 91.5 88.7 95.3 26.5 44.1 45.6 61.2 123.6 36.5 54.8 84.9 107.4 37.8 40.3 63.2 68.6 167.9 54.3 55.2 78.4 33.8 41.7 117.7 51.0 85.5 20.9 31.4 37.0 31.6 39.7 38.4 46.7 77.9 39.3 28.8 43.0 48.3 71.7 47.1 47.5 92.6 42.4 131.6 26.2 6.8 41.3 7.6 38.8 41.5 43.6 71.3 44.6 40.2 66.0 59.7 51.8 41.4 2.1 58.3 31.5 40.2 47.7 45.4 9.5 9.5 10.0 10.4 9.5 10.9 10.4 9.8 10.1 9.7 10.5 9.8 25.0 35.3 30.1 16.0 23.2 61.8 68.8 97.2 47.3 29.5 23.9 43.2 39.0 21.5 46.5 35.0 18.8 67.8 22.1 8.6 135.0 51.7 3.9 23.7 34.8 24.0 13.1 19.6 19.9 46.7 62.4 32.7 23.0 21.7 15.2 33.0 18.2 28.6 46.5 20.2 22.5 19.3 79.3 14.2 22.6 8.3 47.8 17.4 26.6 8.4 20.6 37.6 33.0 10.6 14.0 41.7 10.3 41.0 19.4 74.8 17.7 47.4 34.3 23.4 13.1 25.7 53.9 53.7 66.3 35.5 74.2 63.1 26.2 52.2 24.3 56.3 EXPH5 SLAC2-B ENSG00000110723 "Exophilin 5" Q8NEV8 11 108505435-108593768 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Epidermolysis bullosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 67.7;skin 1: 25.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 147.4;Basal keratinocytes: 107.7;Glandular and luminal cells: 89.5;Respiratory ciliated cells: 98.5" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 15 "cerebellum: 67.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 7.9;hTERT-HME1: 11.2;RT4: 20.5;SK-BR-3: 9.7" "Group enriched" "Detected in many" 4 "cerebellum: 20.9;cerebral cortex: 6.7" "Region enriched" "Detected in many" 8 "cerebellum: 30.9" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" "unprognostic (1.34e-3)" "unprognostic (8.36e-2)" "unprognostic (1.18e-1)" "prognostic favorable (3.42e-6)" "unprognostic (2.91e-1)" "prognostic favorable (1.46e-4)" "unprognostic (4.57e-3)" "prognostic favorable (5.12e-4)" "unprognostic (1.26e-1)" "unprognostic (3.03e-1)" "unprognostic (5.56e-3)" "unprognostic (1.33e-1)" "prognostic favorable (2.43e-4)" "unprognostic (1.18e-2)" "unprognostic (2.57e-1)" "unprognostic (3.36e-1)" "unprognostic (4.51e-1)" 0.4 0.1 1.3 0.5 2.5 0.2 2.9 67.7 2.3 2.2 12.8 3.9 0.7 0.7 2.7 7.4 1.7 0.3 0.2 2.1 1.9 2.4 7.7 3.9 0.1 1.5 3.6 0.3 1.0 4.7 0.5 2.8 4.6 1.5 4.4 0.3 4.4 0.3 0.1 25.8 0.8 0.4 1.1 0.2 3.2 0.7 1.7 0.8 1.0 0.2 1.4 0.7 3.8 3.4 3.9 0.4 0.2 0.1 0.0 0.1 3.2 0.2 0.1 0.0 0.6 1.0 5.9 0.0 0.2 0.2 0.9 7.9 5.7 2.1 0.2 0.1 1.7 1.6 0.8 0.0 0.5 0.8 0.1 0.1 3.3 0.0 11.2 0.5 0.0 1.3 3.0 0.0 3.1 0.6 1.0 0.0 0.2 6.4 2.4 0.0 0.1 0.0 0.6 20.5 1.4 0.8 1.0 9.7 0.2 1.1 6.4 0.1 0.1 0.0 2.3 0.0 1.1 0.1 0.0 0.0 0.1 0.4 0.0 0.8 0.1 0.1 0.1 0.0 0.0 0.2 0.2 0.1 0.1 0.1 0.5 0.5 0.8 0.9 0.1 0.2 0.0 0.1 1.3 2.5 67.7 2.3 2.1 1.9 1.5 3.6 4.6 1.1 1.7 3.4 0.6 147.4 60.0 18.6 0.9 107.7 12.9 16.6 58.6 0.6 14.1 8.6 5.7 4.3 65.3 20.2 14.6 44.5 2.4 47.9 3.9 5.4 10.3 74.8 7.8 2.5 4.9 3.2 9.0 4.9 4.9 5.6 20.9 89.5 1.3 0.9 0.7 24.2 3.8 0.0 4.9 38.6 14.2 0.6 15.2 2.3 0.6 1.8 5.4 16.9 1.3 0.5 1.0 3.0 0.6 3.6 17.5 0.0 1.5 30.4 1.9 3.7 98.5 1.4 0.0 0.3 2.1 1.1 0.5 46.9 72.2 54.6 2.8 0.4 29.1 19.3 EXTL1 "EXTL, MGC70794" ENSG00000158008 "Exostosin like glycosyltransferase 1" Q92935 1 26019884-26036464 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 14.2;skeletal muscle: 12.7;tongue: 29.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 15.3;Breast glandular cells: 8.8;Excitatory neurons: 22.7;Horizontal cells: 10.1;Melanocytes: 7.2;Oligodendrocyte precursor cells: 10.6" "Cancer enriched" "Detected in some" 13 "melanoma: 21.7" "Group enriched" "Detected in many" 11 "amygdala: 10.3;basal ganglia: 9.8;cerebral cortex: 14.2;hippocampal formation: 11.5;white matter: 6.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 10 "WM-115: 150.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010726, HPA037749" Uncertain Approved Vesicles,Centrosome "Intracellular and membrane" NA NA 79000 "Cluster 47: Non-specific - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 30: Mammary glandular cells - Lactation" Centrosome Vesicles "HPA010726: , HPA037749: AB_10805350" "unprognostic (2.00e-1)" "unprognostic (1.10e-2)" "unprognostic (8.16e-3)" "unprognostic (1.47e-2)" "unprognostic (2.47e-2)" "unprognostic (6.14e-3)" "unprognostic (3.78e-2)" "unprognostic (1.99e-1)" "unprognostic (1.99e-1)" "unprognostic (6.70e-2)" "unprognostic (1.44e-2)" "unprognostic (3.46e-1)" "unprognostic (1.12e-2)" "unprognostic (1.40e-3)" "unprognostic (2.27e-2)" "unprognostic (2.91e-1)" "unprognostic (1.35e-2)" 0.2 1.0 10.3 0.0 9.8 0.0 0.8 0.0 14.2 0.4 0.0 1.0 0.1 3.6 0.1 0.5 0.7 0.3 3.5 11.5 0.0 0.4 0.0 0.2 0.2 0.1 0.6 1.1 1.5 0.0 0.9 0.3 0.4 0.4 0.0 0.8 0.5 0.2 12.7 2.3 0.3 1.3 0.0 3.5 0.3 0.6 0.9 0.0 0.2 29.8 0.0 0.3 0.4 6.9 0.2 0.0 0.1 0.6 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.0 0.1 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.0 0.0 0.0 0.7 0.0 0.2 0.2 0.1 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 14.7 0.0 0.0 0.0 0.2 0.6 0.0 0.2 2.4 0.2 0.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 150.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.3 9.8 0.0 14.2 11.5 0.0 0.1 0.6 0.4 0.0 0.9 6.9 0.1 0.0 0.0 2.3 0.0 0.1 0.0 0.0 0.0 15.3 8.8 1.8 3.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.6 0.1 0.0 0.0 22.7 0.0 0.0 0.4 0.0 0.2 0.0 0.4 0.0 0.0 0.1 10.1 5.1 0.0 0.0 0.0 0.3 0.6 1.5 0.0 7.2 2.8 0.0 0.4 0.0 10.6 1.9 0.0 0.0 2.6 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.4 0.4 0.2 0.2 0.0 0.0 1.0 0.0 1.1 0.1 0.1 F2RL1 "GPR11, PAR2" ENSG00000164251 "F2R like trypsin receptor 1" P55085 5 76818933-76835315 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Immunity, Inflammatory response, Innate immunity" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 59.4;stomach 1: 44.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 109.9;Distal enterocytes: 124.7;Gastric mucus-secreting cells: 74.5;Glandular and luminal cells: 74.7;Paneth cells: 86.1;Suprabasal keratinocytes: 168.4;Urothelial cells: 116.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 42.0" "Lineage enriched" "Detected in many" 4 "granulocytes: 42.0" "Cell line enhanced" "Detected in many" "PC-3: 126.0;RPTEC TERT1: 205.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB012989, HPA014091" Approved Approved "Plasma membrane" NA Yes "Cluster 9: Neutrophils - Innate immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "CAB012989: AB_2533199, HPA014091: AB_2668939" "unprognostic (1.29e-2)" "unprognostic (4.05e-2)" "prognostic favorable (3.88e-4)" "unprognostic (1.98e-2)" "unprognostic (8.22e-2)" "prognostic unfavorable (5.88e-4)" "unprognostic (1.36e-1)" "prognostic unfavorable (8.92e-4)" "unprognostic (6.13e-2)" "unprognostic (4.07e-1)" "unprognostic (2.16e-3)" "unprognostic (1.52e-2)" "prognostic favorable (5.86e-7)" "unprognostic (1.11e-1)" "unprognostic (1.74e-1)" "unprognostic (3.76e-2)" "unprognostic (9.73e-2)" 1.0 1.3 0.8 6.2 0.9 1.7 8.0 0.5 0.8 3.6 8.9 59.4 45.8 2.9 4.8 8.2 8.2 29.9 4.6 0.5 0.8 31.8 7.1 4.1 1.4 1.7 2.2 0.5 23.6 5.2 1.5 3.9 1.4 5.0 53.0 2.6 8.9 11.5 0.3 37.5 41.0 2.7 1.0 3.8 44.0 0.6 0.9 1.1 8.3 0.2 1.6 27.5 5.8 0.8 32.7 52.1 4.3 0.2 1.5 4.0 33.1 1.6 17.1 0.9 2.7 45.0 81.8 0.0 69.5 3.7 78.1 54.4 27.1 24.0 1.5 0.1 26.8 0.8 1.0 32.8 10.6 0.0 0.3 5.5 67.3 8.0 49.8 8.0 84.9 7.8 0.4 0.0 0.1 17.6 3.8 0.1 5.7 17.9 126.0 0.1 0.0 0.8 205.9 58.5 2.1 0.4 12.3 12.6 0.3 48.5 5.3 0.3 57.1 0.1 31.8 0.1 0.3 4.8 1.0 0.1 18.7 0.0 1.4 11.9 10.0 1.8 0.4 3.2 2.1 0.5 3.8 1.9 4.7 0.1 3.4 2.1 42.0 0.7 0.5 0.5 1.0 4.0 0.8 0.9 0.5 0.8 0.5 0.8 1.7 2.2 1.4 1.0 0.9 0.8 0.3 9.6 3.7 0.0 0.9 109.9 17.8 4.5 10.8 0.5 10.5 6.3 0.3 32.9 12.7 31.3 0.0 5.4 0.2 124.7 1.9 28.0 0.0 40.9 5.1 1.2 13.1 2.5 0.2 15.0 7.9 2.9 74.5 74.7 2.5 1.0 1.1 9.6 0.9 0.0 1.4 50.8 4.1 1.9 3.8 0.0 0.0 2.1 1.8 1.0 2.6 0.0 0.0 0.0 0.0 44.7 86.1 0.0 0.1 34.1 62.9 19.3 25.0 2.0 0.0 0.4 2.8 0.9 1.3 37.0 168.4 2.1 2.1 0.1 50.7 116.0 F5 ENSG00000198734 "Coagulation factor V" P12259 1 169511951-169586588 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "choroid plexus: 142.8;liver: 176.2;placenta: 46.9" "Cell type enhanced" "Detected in many" "Cholangiocytes: 74.4;Cytotrophoblasts: 82.7;Hepatocytes: 253.4;Syncytiotrophoblasts: 59.5" "Cancer enriched" "Detected in many" 7 "liver cancer: 69.6" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "classical monocyte: 4.1;eosinophil: 8.1;neutrophil: 7.0;T-reg: 6.2" "Group enriched" "Detected in many" 13 "granulocytes: 8.1;monocytes: 4.1;T-cells: 6.2" "Group enriched" "Detected in some" 23 "Hep G2: 32.8;OE19: 125.5" "Group enriched" "Detected in many" 5 "basal ganglia: 2.7;hippocampal formation: 6.6;pons and medulla: 4.4;thalamus: 5.4" "Group enriched" "Detected in all" 7 "amygdala: 39.9;basal ganglia: 35.0;cerebral cortex: 67.9;hippocampal formation: 61.4;olfactory bulb: 27.6" HPA002036 Approved "Golgi apparatus" "Secreted to blood" NA NA 7670000000 13000000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 2: Hepatocytes - Metabolism" "Golgi apparatus" "HPA002036: AB_1078787" "unprognostic (3.67e-2)" "unprognostic (2.77e-4)" "unprognostic (5.42e-2)" "unprognostic (2.56e-4)" "unprognostic (2.03e-1)" "unprognostic (2.39e-4)" "unprognostic (3.46e-3)" "unprognostic (9.25e-3)" "unprognostic (2.02e-1)" "unprognostic (8.99e-3)" "unprognostic (6.55e-3)" "unprognostic (1.32e-1)" "unprognostic (2.01e-2)" "prognostic unfavorable (3.39e-4)" "unprognostic (7.15e-2)" "unprognostic (3.41e-1)" "unprognostic (4.31e-1)" 1.1 0.0 0.3 3.2 1.4 3.7 0.6 4.4 1.3 0.1 142.8 0.3 0.9 0.1 0.2 0.2 3.5 17.6 2.7 4.4 1.6 1.5 176.2 0.9 2.2 1.9 2.2 0.0 0.8 0.0 1.6 46.9 2.4 1.3 0.6 1.0 6.2 0.0 0.2 1.3 0.3 1.1 0.8 1.8 4.9 0.5 2.2 0.5 0.4 0.2 2.3 3.8 0.1 4.2 0.0 0.6 0.0 0.0 0.1 0.0 3.2 0.0 0.0 0.0 0.0 0.2 1.5 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 32.8 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 125.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 4.1 8.1 0.0 0.2 0.0 0.0 1.4 0.2 0.4 0.0 0.3 0.0 7.0 0.0 0.0 0.0 6.2 1.1 0.3 1.4 4.4 1.3 4.4 1.6 1.9 2.2 2.4 0.8 2.2 4.2 0.0 3.2 0.6 1.6 0.7 0.1 6.1 0.0 0.0 0.3 0.7 0.3 9.4 74.4 1.9 0.0 2.1 82.7 0.1 0.3 0.0 2.4 2.4 0.9 0.0 2.4 25.2 0.0 5.4 0.2 2.3 5.3 4.1 0.2 0.0 2.8 3.6 253.4 5.3 0.0 2.6 0.1 0.0 12.3 0.4 0.3 0.0 7.1 3.6 0.0 18.2 1.0 2.1 0.5 1.0 1.9 0.0 0.0 0.1 1.8 0.0 0.2 3.1 0.1 0.0 2.4 0.2 0.5 0.5 0.0 0.0 59.5 2.5 0.0 0.0 11.8 FA2H "FAAH, FAXDC1, FLJ25287, SPG35" ENSG00000103089 "Fatty acid 2-hydroxylase" Q7L5A8 16 74712955-74774831 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Sphingolipid metabolism" Oxidoreductase "Disease variant, Hereditary spastic paraplegia, Leukodystrophy, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 183.9;stomach 1: 61.1" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 85.1;Oligodendrocyte precursor cells: 61.3;Oligodendrocytes: 307.9;Paneth cells: 75.2;Urothelial cells: 192.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 38.1;HAP1: 48.6;JURKAT: 89.8;OE19: 61.5;SK-BR-3: 28.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056614, HPA077840" Approved Uncertain "Nuclear membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 70: Brain - Nervous system development" "Cluster 21: OE19 - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" "Nuclear membrane" "HPA056614: AB_2683191, HPA077840: AB_2686858" "unprognostic (1.33e-1)" "unprognostic (4.97e-2)" "unprognostic (9.19e-2)" "unprognostic (1.08e-1)" "unprognostic (1.60e-1)" "unprognostic (5.85e-2)" "unprognostic (1.48e-2)" "unprognostic (2.47e-2)" "unprognostic (1.82e-1)" "unprognostic (1.28e-1)" "prognostic unfavorable (3.74e-4)" "unprognostic (6.01e-2)" "prognostic favorable (5.01e-6)" "unprognostic (1.50e-1)" "unprognostic (1.76e-1)" "unprognostic (1.83e-2)" "unprognostic (2.11e-3)" 0.3 0.3 41.7 4.3 89.1 0.3 2.8 77.9 63.0 1.9 11.7 21.2 10.3 0.2 2.2 7.9 1.8 17.8 0.3 46.1 56.1 8.2 0.2 1.4 0.7 129.2 79.6 0.0 8.4 10.1 0.6 0.7 106.0 1.9 19.4 0.4 11.0 0.7 0.0 8.5 14.4 1.1 65.2 0.5 61.1 2.9 75.2 4.7 2.0 0.1 5.9 26.3 2.2 183.9 9.2 38.1 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.5 0.0 20.8 21.0 0.0 0.2 0.0 2.0 3.6 48.6 0.6 0.1 0.0 1.6 0.0 2.7 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.1 0.0 0.0 89.8 0.0 0.0 0.0 15.2 0.8 0.0 0.9 61.5 2.1 0.0 0.0 1.6 23.4 15.6 6.5 0.0 0.0 28.8 0.0 1.3 8.6 0.0 0.0 0.0 0.1 0.0 0.2 1.4 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.7 89.1 77.9 63.0 46.1 56.1 129.2 79.6 106.0 65.2 75.2 183.9 0.0 0.0 1.3 1.0 2.6 0.5 11.1 8.5 1.8 0.0 5.0 3.3 0.2 8.6 14.6 0.0 0.0 0.5 0.2 43.0 7.9 13.5 10.8 2.4 0.5 0.2 6.7 0.0 0.7 14.2 0.2 1.1 85.1 4.5 0.0 0.1 0.0 0.0 0.1 0.0 0.9 34.8 4.1 0.0 0.0 4.0 0.0 0.2 3.6 0.0 0.0 0.0 0.0 61.3 307.9 38.4 75.2 0.4 6.2 22.9 17.6 0.2 10.5 0.0 0.0 0.0 0.6 2.4 3.3 12.4 0.9 0.1 0.2 0.0 15.3 192.8 FADS1 "D5D, FADS6, FADSD5, LLCDL1, TU12" ENSG00000149485 "Fatty acid desaturase 1" O60427 11 61799627-61829318 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Transport" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 91.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC TERT1: 521.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042705 Approved NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 65: Plasmacytoid DCs - Unknown function" "HPA042705: AB_10795709" "unprognostic (8.28e-2)" "unprognostic (3.54e-1)" "unprognostic (1.29e-1)" "unprognostic (1.99e-1)" "unprognostic (8.17e-3)" "unprognostic (1.40e-1)" "unprognostic (1.99e-2)" "unprognostic (3.23e-3)" "unprognostic (7.88e-2)" "unprognostic (1.94e-2)" "unprognostic (4.10e-2)" "unprognostic (2.00e-1)" "prognostic unfavorable (1.95e-9)" "unprognostic (2.29e-2)" "unprognostic (3.59e-2)" "prognostic unfavorable (2.79e-4)" "prognostic unfavorable (1.33e-4)" 26.2 67.7 43.1 19.8 39.2 9.7 13.6 38.4 40.7 19.6 70.7 9.5 5.5 21.3 6.6 5.2 17.4 14.5 22.6 39.3 58.5 9.7 52.8 20.3 9.8 57.9 62.1 27.5 10.0 27.2 21.3 21.1 52.2 19.6 4.9 35.1 6.4 15.8 17.5 15.5 6.7 20.5 46.4 8.0 9.4 11.9 68.7 8.1 6.0 7.8 9.2 12.7 10.2 56.0 66.3 170.1 159.1 41.1 313.2 521.2 46.4 42.0 204.5 69.9 118.9 53.3 143.2 2.3 43.4 60.5 177.2 84.7 130.8 114.1 51.7 12.2 18.4 107.9 191.2 98.9 169.1 23.4 10.4 238.1 38.3 154.7 74.7 73.8 64.1 104.7 59.9 118.6 70.1 18.6 78.6 23.6 94.2 5.5 63.0 85.4 162.5 231.2 81.5 29.0 80.7 89.6 106.7 1.7 90.0 58.4 38.6 98.6 62.1 71.8 70.8 74.2 50.6 112.9 111.3 55.4 42.6 108.9 61.4 7.5 33.2 6.2 12.1 40.4 2.6 2.5 4.0 4.9 28.0 8.7 2.3 5.4 2.6 6.9 17.4 23.6 2.9 15.7 43.1 39.2 38.4 40.7 39.3 58.5 57.9 62.1 52.2 46.4 68.7 56.0 10.3 6.4 77.9 28.7 3.2 2.7 2.5 48.5 1.2 78.9 2.6 3.7 30.4 8.6 25.3 12.9 27.1 9.5 12.4 0.9 0.0 15.2 8.7 4.9 30.7 16.6 9.7 46.3 9.4 33.4 50.0 34.9 6.1 7.8 37.9 65.3 9.3 74.5 37.2 69.0 14.7 0.6 16.2 21.7 21.0 16.4 29.8 27.6 32.0 12.2 32.0 70.5 6.2 13.6 27.4 7.6 0.0 21.4 2.1 6.4 0.1 1.1 8.0 91.9 0.0 40.3 31.9 6.5 17.5 2.3 1.4 9.3 5.5 75.2 1.4 1.6 FADS2 "D6D, DES6, FADSD6, LLCDL2, SLL0262, TU13" ENSG00000134824 "Fatty acid desaturase 2" O95864 11 61792980-61867354 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Transport" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 364.1" "Cell type enhanced" "Detected in many" "Astrocytes: 69.9;Endometrial stromal cells: 57.7;Hepatocytes: 55.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 1141.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006741 Approved NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA006741: AB_1078796" "unprognostic (2.37e-2)" "unprognostic (1.02e-1)" "unprognostic (8.34e-2)" "unprognostic (4.33e-3)" "unprognostic (4.63e-2)" "unprognostic (2.42e-2)" "unprognostic (4.51e-2)" "unprognostic (4.35e-3)" "unprognostic (2.01e-1)" "unprognostic (4.21e-2)" "unprognostic (8.95e-3)" "unprognostic (7.80e-2)" "prognostic unfavorable (1.00e-7)" "unprognostic (6.19e-2)" "unprognostic (1.34e-1)" "unprognostic (1.41e-2)" "prognostic unfavorable (3.42e-4)" 23.7 364.1 140.2 34.7 126.7 28.0 59.6 128.5 135.0 68.0 157.0 24.2 31.9 86.3 27.7 10.6 34.6 20.2 27.7 131.8 164.8 20.3 126.7 33.4 16.5 175.1 186.2 29.1 9.8 80.0 50.8 40.6 155.1 97.7 13.2 41.5 24.3 188.7 12.3 131.6 15.9 125.3 152.0 11.5 14.1 27.8 222.9 34.1 10.4 8.8 31.2 24.6 27.9 134.2 14.6 492.6 655.8 345.0 551.3 1141.8 167.2 86.3 658.3 109.0 288.2 31.4 149.6 3.8 11.4 172.3 167.8 15.7 436.4 709.5 52.7 6.9 11.8 297.9 106.5 72.0 421.9 18.9 15.9 430.9 25.8 383.4 39.1 170.3 324.4 254.4 17.9 212.1 52.0 13.5 166.4 104.7 291.5 0.7 150.1 206.1 13.9 663.1 392.1 4.4 197.4 260.8 49.9 1.4 23.5 164.0 21.5 197.7 139.2 14.0 120.5 9.8 13.1 115.7 110.3 39.7 13.0 96.3 131.2 4.4 6.0 6.9 8.5 8.7 2.0 1.4 3.1 4.6 10.1 3.7 1.8 3.8 2.8 6.6 7.4 13.0 2.9 4.9 140.2 126.7 128.5 135.0 131.8 164.8 175.1 186.2 155.1 152.0 222.9 134.2 3.2 9.6 18.8 69.9 2.0 1.7 1.3 26.9 0.0 9.1 4.7 3.0 4.2 1.5 15.1 3.7 4.2 1.7 5.2 0.5 0.0 6.9 2.2 4.7 57.7 12.2 5.4 26.7 7.4 17.8 22.0 21.0 5.1 9.5 5.1 28.3 2.5 55.8 20.5 5.0 7.7 0.2 22.4 7.2 3.1 5.3 25.7 7.0 8.8 15.0 20.7 32.1 8.2 38.7 11.9 5.1 0.0 23.7 1.4 16.9 0.1 0.7 5.4 13.2 0.0 23.8 29.5 1.3 0.5 1.2 0.6 3.1 2.5 28.3 2.0 0.9 FAM25A bA96C23.5 ENSG00000188100 "Family with sequence similarity 25 member A" B3EWG3 10 87020294-87024730 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 143.3;esophagus: 519.5;salivary gland: 140.0;skin 1: 175.0;vagina: 193.1" "Group enriched" "Detected in some" 4 "Suprabasal keratinocytes: 49.6;Syncytiotrophoblasts: 16.1" "Cancer enriched" "Detected in many" 4 "head and neck cancer: 53.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "A-431: 30.3;SK-BR-3: 70.0" "Low region specificity" "Detected in single" HPA044808 Uncertain NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA044808: AB_2679096" "unprognostic (9.94e-2)" "unprognostic (2.57e-1)" "unprognostic (7.62e-2)" "unprognostic (1.03e-1)" "unprognostic (2.02e-1)" "unprognostic (1.05e-5)" "unprognostic (1.21e-1)" 0.3 2.0 0.0 0.0 0.0 0.0 5.7 0.0 0.1 143.3 0.0 0.1 0.0 0.1 0.0 519.5 0.1 0.1 0.2 0.0 0.1 0.1 0.2 0.0 0.0 0.2 0.0 0.1 0.2 0.0 0.1 1.5 0.0 0.1 0.0 0.0 140.0 0.0 1.2 175.0 0.0 0.0 0.0 0.1 0.5 0.1 0.1 1.4 0.0 0.0 63.6 0.1 193.1 0.1 30.3 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 7.9 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.0 0.3 0.0 0.0 0.2 0.0 0.0 9.0 0.1 0.0 0.0 0.2 2.0 0.0 0.3 0.0 1.6 1.2 0.0 0.0 0.0 70.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.6 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 3.9 0.1 0.3 0.2 0.1 0.1 0.0 0.0 0.0 0.2 0.2 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 1.8 2.9 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.1 49.6 16.1 0.0 0.0 0.0 1.9 FAM83B "C6orf143, FLJ30642" ENSG00000168143 "Family with sequence similarity 83 member B" Q5T0W9 6 54846771-54945099 "Predicted intracellular proteins" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 14.5;skin 1: 25.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 33.8;Basal prostatic cells: 32.5;Basal squamous epithelial cells: 43.3;Squamous epithelial cells: 31.9;Suprabasal keratinocytes: 41.1;Urothelial cells: 25.4" "Cancer enhanced" "Detected in many" "head and neck cancer: 15.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 13.3;HaCaT: 18.1;HBEC3-KT: 9.8;hTCEpi: 19.7;hTERT-HME1: 23.8;RT4: 19.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA031464, HPA031465" Enhanced NA NA "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "HPA031464: AB_10599973, HPA031465: AB_10601566" "unprognostic (2.29e-1)" "unprognostic (3.93e-2)" "unprognostic (3.71e-2)" "unprognostic (1.03e-2)" "unprognostic (1.71e-2)" "prognostic unfavorable (1.48e-4)" "unprognostic (7.27e-2)" "unprognostic (5.77e-3)" "prognostic unfavorable (7.60e-4)" "unprognostic (1.62e-1)" "unprognostic (3.19e-2)" "unprognostic (1.85e-1)" "unprognostic (4.35e-1)" "unprognostic (2.16e-1)" "prognostic unfavorable (1.86e-5)" 0.0 0.0 0.1 1.0 0.1 0.1 2.2 0.1 0.1 3.8 0.0 8.0 7.4 0.3 1.2 14.5 1.6 2.1 1.1 0.0 0.0 2.5 0.1 0.1 0.0 0.0 0.7 0.0 1.5 0.0 0.0 4.3 0.1 1.8 8.2 0.1 4.7 1.1 0.7 25.9 7.4 0.2 0.0 0.0 3.9 0.6 0.0 2.3 3.6 0.1 3.6 4.3 9.8 0.2 13.3 0.2 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 6.5 3.6 0.0 0.0 0.0 0.1 18.1 0.0 9.8 0.1 0.0 2.2 0.0 2.5 0.0 0.0 0.0 0.0 0.0 19.7 0.0 23.8 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.6 4.1 0.0 0.0 0.0 0.0 9.1 19.2 0.2 0.0 2.9 0.6 0.0 3.3 4.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 33.8 32.5 6.6 43.3 0.0 1.5 3.0 3.1 5.7 6.5 7.3 0.0 11.2 0.1 9.0 0.0 6.1 6.3 8.8 0.8 0.3 1.2 0.0 0.2 3.5 11.9 0.4 9.2 8.1 0.0 0.0 0.4 0.0 0.6 0.0 0.1 5.4 6.1 0.0 1.5 2.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 17.4 0.0 0.1 9.1 12.6 0.0 1.8 0.0 0.0 0.0 0.1 0.1 0.6 31.9 41.1 18.7 0.1 0.0 8.8 25.4 FAR2 "FLJ10462, MLSTD1, SDR10E2" ENSG00000064763 "Fatty acyl-CoA reductase 2" Q96K12 12 29149103-29340980 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 36.2;intestine: 34.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 114.3;Inhibitory neurons: 172.1;Microglial cells: 63.7;Syncytiotrophoblasts: 193.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 50.0" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 76.2;HUVEC TERT2: 84.0;NB-4: 74.2;SK-BR-3: 89.6;TIME: 68.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015884 Approved Approved "Nucleoli,Golgi apparatus" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 37: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" Nucleoli "HPA015884: AB_1853998" "unprognostic (6.32e-2)" "unprognostic (2.40e-2)" "unprognostic (1.50e-3)" "unprognostic (3.33e-3)" "unprognostic (2.41e-1)" "unprognostic (4.13e-3)" "unprognostic (4.30e-2)" "unprognostic (1.18e-1)" "unprognostic (3.11e-2)" "unprognostic (6.37e-2)" "unprognostic (5.70e-3)" "unprognostic (1.92e-1)" "prognostic unfavorable (4.93e-4)" "unprognostic (2.10e-1)" "unprognostic (2.23e-1)" "unprognostic (1.33e-1)" "unprognostic (5.22e-3)" 8.3 9.0 4.1 9.3 8.3 17.1 9.3 1.2 8.5 4.3 0.0 34.5 17.6 5.6 36.2 7.4 3.6 5.2 6.6 6.2 9.2 5.0 3.8 11.3 7.9 1.2 2.9 2.3 3.2 1.3 2.4 18.1 1.3 2.6 28.2 9.4 4.4 1.9 6.3 9.0 19.2 7.6 1.4 12.2 4.9 9.2 5.2 7.0 4.4 2.6 3.0 6.5 3.7 4.9 2.5 4.9 4.9 1.2 6.8 26.9 2.1 21.3 24.7 5.8 5.4 8.2 28.0 3.7 5.4 3.4 4.3 1.5 13.4 0.2 1.4 1.8 32.2 76.2 10.7 2.7 14.7 30.0 24.0 7.5 0.2 8.7 11.0 14.3 84.0 2.9 6.6 2.7 0.9 0.8 19.9 74.2 19.3 1.6 54.5 16.1 7.9 3.1 25.7 7.2 8.6 7.9 4.8 89.6 37.8 9.7 4.1 28.2 68.2 15.6 4.6 5.6 9.3 4.4 4.9 1.8 24.5 38.5 13.7 3.8 22.8 50.0 5.0 13.9 3.4 2.0 8.3 6.2 8.1 1.8 2.9 3.2 41.0 4.0 8.0 3.1 16.1 9.6 4.1 8.3 1.2 8.5 6.2 9.2 1.2 2.9 1.3 1.4 5.2 4.9 9.1 0.0 3.3 7.8 0.6 1.3 0.1 0.2 0.6 2.0 1.4 0.8 12.1 0.0 1.4 0.0 0.0 16.0 1.1 35.7 0.0 0.1 31.5 0.4 2.9 11.9 7.2 4.6 114.3 0.2 19.6 4.8 5.6 0.4 10.8 0.0 9.7 0.0 19.3 5.0 172.1 21.8 0.0 22.2 3.7 6.4 1.2 12.2 16.0 63.7 6.9 0.5 1.0 24.6 6.9 3.3 36.8 0.4 8.0 0.4 15.1 0.4 3.2 1.2 0.0 4.2 3.6 16.6 1.0 0.3 0.3 193.9 4.2 0.9 23.7 0.3 FASN "FAS, SDR27X1" ENSG00000169710 "Fatty acid synthase" P49327 17 82078338-82098294 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "Hydrolase, Lyase, Multifunctional enzyme, Oxidoreductase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 372.8;breast: 271.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 126.0;Breast glandular cells: 442.9;Breast myoepithelial cells: 165.4;Hepatocytes: 244.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "SK-BR-3: 1109.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005192, HPA006461, CAB015417, HPA056108" Enhanced Enhanced "Plasma membrane,Cytosol" No No 3400000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 30: Mammary glandular cells - Lactation" "Plasma membrane, Cytosol" "CAB005192: AB_2101095, CAB015417: AB_2231427, HPA006461: AB_1848437, HPA056108: AB_2683039" "unprognostic (3.35e-2)" "prognostic unfavorable (1.42e-5)" "unprognostic (9.69e-3)" "unprognostic (4.09e-2)" "unprognostic (3.46e-3)" "unprognostic (1.55e-2)" "unprognostic (3.09e-2)" "unprognostic (4.74e-3)" "unprognostic (3.15e-1)" "unprognostic (3.15e-1)" "unprognostic (2.87e-3)" "unprognostic (1.05e-1)" "prognostic unfavorable (7.16e-5)" "unprognostic (4.50e-2)" "unprognostic (9.62e-2)" "unprognostic (1.35e-2)" "unprognostic (7.03e-3)" 372.8 30.9 25.0 14.9 44.2 18.7 271.6 67.3 49.9 31.7 0.0 25.5 11.5 18.0 6.2 63.6 15.2 6.6 21.9 39.9 15.0 11.8 191.4 54.1 7.2 84.4 75.7 16.3 18.6 8.5 72.4 12.1 101.7 69.0 3.0 4.3 38.3 14.3 27.9 89.4 28.8 5.3 12.5 8.8 63.6 11.9 33.7 9.6 21.2 2.3 3.0 27.0 31.8 60.8 179.1 182.0 81.7 56.7 130.1 87.2 176.9 34.3 43.3 35.5 64.6 190.6 116.7 58.8 29.2 26.3 99.5 144.0 79.2 157.8 6.5 30.0 358.0 123.9 140.0 257.2 36.8 67.5 19.2 84.2 40.4 90.8 21.0 12.1 40.1 54.8 193.2 50.7 12.6 304.1 78.9 105.5 161.1 28.1 107.1 64.1 47.8 116.5 40.3 220.7 205.0 117.0 50.6 1109.2 93.6 29.5 199.4 123.4 71.1 52.3 107.0 45.2 88.4 68.5 17.1 60.6 31.2 71.1 79.5 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.2 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 25.0 44.2 67.3 49.9 39.9 15.0 84.4 75.7 101.7 12.5 33.7 60.8 9.6 25.6 126.0 28.4 7.4 7.8 12.7 33.2 8.0 28.7 442.9 165.4 5.9 21.5 28.4 11.0 6.2 32.0 12.8 35.7 3.9 19.2 1.5 19.6 19.8 10.8 18.1 20.6 11.9 29.2 77.7 13.4 33.6 17.1 12.7 29.9 10.8 244.1 13.9 30.3 12.5 22.3 22.4 9.8 6.2 3.4 16.4 7.0 17.8 4.7 6.2 14.1 8.2 11.6 17.6 19.1 23.6 11.3 9.7 60.4 6.5 5.9 23.7 13.1 0.0 9.0 14.9 1.8 11.7 34.1 13.8 29.6 10.6 27.9 27.4 19.6 FBP2 ENSG00000130957 "Fructose-bisphosphatase 2" O00757 9 94558720-94593824 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Gluconeogenesis" "Allosteric enzyme, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "skeletal muscle: 753.6;tongue: 385.3" "Group enriched" "Detected in some" 7 "Gastric mucus-secreting cells: 11.2;Skeletal myocytes: 8.7;Spermatogonia: 8.5" "Cancer enhanced" "Detected in some" "stomach cancer: 1.2" "Region enriched" "Detected in some" 4 "hippocampal formation: 6.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 3.9;CACO-2: 2.1;HMC-1: 2.2;MCF7: 3.0;OE19: 2.9;PC-3: 2.0;SiHa: 2.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA012513, HPA077371" Enhanced Approved "Plasma membrane,Cytosol" NA NA 960000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 28: BEWO - Transcription regulation" "Cluster 37: Myocytes - Muscle contraction" "Plasma membrane, Cytosol" "HPA012513: AB_1848446, HPA077371: " "unprognostic (3.88e-2)" "unprognostic (3.54e-4)" "unprognostic (2.38e-1)" "unprognostic (6.03e-2)" "unprognostic (2.21e-1)" "unprognostic (1.54e-2)" "unprognostic (9.40e-4)" "unprognostic (3.95e-3)" "unprognostic (5.11e-2)" "unprognostic (2.39e-2)" "unprognostic (4.69e-2)" "unprognostic (2.53e-1)" "unprognostic (1.36e-2)" "unprognostic (2.03e-1)" "unprognostic (1.48e-4)" 0.1 0.9 0.1 0.1 0.0 0.0 0.2 1.2 0.1 0.0 69.2 0.3 5.3 0.0 0.0 8.1 0.0 0.1 0.2 6.1 0.0 0.2 0.2 0.4 0.4 0.7 0.3 0.0 4.3 49.7 0.0 0.1 0.1 1.2 0.0 0.0 4.2 3.3 753.6 0.2 0.9 0.0 0.9 0.0 36.1 1.4 1.4 0.2 0.3 385.3 0.9 0.3 0.0 0.0 0.3 1.3 0.0 1.4 0.0 0.0 3.9 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 1.2 1.1 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.0 0.0 0.0 0.0 2.9 2.0 0.0 0.0 0.0 0.0 1.4 0.3 0.0 2.8 0.6 0.0 0.1 0.2 0.1 0.0 0.0 1.2 1.2 0.0 0.0 0.0 0.6 0.1 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.1 6.1 0.0 0.7 0.3 0.1 0.9 1.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.1 0.0 0.0 0.5 1.3 0.0 0.0 11.2 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.1 0.2 8.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 FBXW7 "AGO, CDC4, FBW7, FBX30, FBXW6, FLJ11071, SEL-10, SEL10" ENSG00000109670 "F-box and WD repeat domain containing 7" Q969H0 4 152320544-152536092 "Cancer-related genes, Predicted intracellular proteins" "Biological rhythms, Host-virus interaction, Ubl conjugation pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 66.9" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 201.8;Excitatory neurons: 529.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 23.5" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/70: 79.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013793, CAB029987" Supported Supported Nucleoplasm,Vesicles NA NA "Cluster 11: Basophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Vesicles" "CAB013793: AB_2533451, CAB029987: AB_2246842" "unprognostic (3.32e-1)" "unprognostic (9.02e-2)" "unprognostic (1.84e-2)" "unprognostic (3.08e-2)" "unprognostic (3.87e-1)" "unprognostic (1.36e-3)" "unprognostic (4.37e-1)" "unprognostic (1.94e-1)" "unprognostic (8.28e-2)" "unprognostic (3.29e-1)" "unprognostic (5.32e-3)" "unprognostic (3.19e-2)" "prognostic unfavorable (1.52e-4)" "unprognostic (3.38e-2)" "unprognostic (1.41e-1)" "unprognostic (5.49e-3)" "unprognostic (2.17e-3)" 14.2 9.5 37.9 15.0 43.1 19.8 14.2 54.3 66.9 8.7 6.7 9.5 7.8 8.6 24.3 14.3 15.6 9.2 24.7 48.2 23.0 6.7 11.2 11.4 16.1 17.1 20.9 9.1 12.8 7.8 9.2 9.4 18.1 7.8 10.3 18.0 11.8 7.5 26.0 63.1 10.4 9.1 11.8 16.2 13.0 22.8 29.4 14.7 10.3 19.7 20.3 11.9 10.7 47.4 9.8 8.0 19.1 14.2 12.2 9.4 16.2 13.4 12.9 8.5 8.1 15.7 12.0 24.7 3.9 13.7 6.5 5.2 16.9 30.9 12.1 16.2 8.0 11.9 10.7 10.9 12.7 29.2 10.6 14.8 45.7 15.2 24.4 8.4 15.2 20.5 19.2 25.7 10.8 13.7 34.9 10.6 9.7 8.0 6.1 32.2 8.0 5.3 9.8 17.0 12.7 10.2 8.5 11.3 7.5 21.6 6.4 12.6 15.6 11.3 12.6 5.4 8.2 79.0 47.5 24.4 9.4 9.2 8.3 23.5 2.7 1.6 4.0 3.0 2.7 2.8 3.1 2.7 1.6 1.8 3.4 2.5 4.8 7.1 2.2 2.1 2.9 1.3 37.9 43.1 54.3 66.9 48.2 23.0 17.1 20.9 18.1 11.8 29.4 47.4 29.5 9.6 22.9 80.0 48.1 201.8 36.5 29.9 120.1 74.9 32.1 30.9 61.8 12.8 15.1 9.2 31.3 10.9 54.7 22.2 3.9 14.3 17.4 37.7 37.3 36.1 14.5 30.1 529.6 13.5 39.9 27.2 21.4 61.6 15.8 19.1 17.9 18.3 10.5 11.8 186.5 16.4 32.6 18.8 47.0 10.2 15.2 33.7 28.4 172.4 28.0 37.0 35.0 102.5 99.8 18.7 18.2 11.3 174.5 36.3 8.9 7.5 11.9 41.4 13.1 33.2 25.5 74.1 87.2 57.0 174.9 31.2 46.2 18.7 14.9 70.5 FCER1A FCE1A ENSG00000179639 "Fc fragment of IgE receptor Ia" P12319 1 159289714-159308224 "FDA approved drug targets, Predicted membrane proteins" "IgE-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 33.6" "Cell type enriched" "Detected in many" 7 "Langerhans cells: 1962.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 8 "basophil: 21557.7" "Lineage enriched" "Detected in all" 8 "granulocytes: 21557.7" "Cell line enriched" "Detected in some" 99 "HEL: 447.9" "Not detected" "Not detected" "Not detected" "Not detected" "CAB022102, HPA036051, CAB055526" Approved NA NA "Cluster 38: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 36: HEL - Hemostasis" "Cluster 41: Macrophages - Immune response" "CAB022102: , CAB055526: , HPA036051: AB_2674919" "unprognostic (1.78e-2)" "unprognostic (2.26e-2)" "unprognostic (7.32e-2)" "unprognostic (7.51e-2)" "unprognostic (1.32e-2)" "unprognostic (1.44e-3)" "unprognostic (7.19e-2)" "unprognostic (1.97e-3)" "unprognostic (2.44e-1)" "unprognostic (7.20e-2)" "unprognostic (8.54e-2)" "unprognostic (2.74e-1)" "prognostic favorable (1.20e-4)" "unprognostic (1.68e-2)" "unprognostic (1.18e-1)" "unprognostic (2.70e-1)" "unprognostic (3.39e-2)" 3.9 1.7 0.4 5.7 0.4 14.2 17.3 0.5 0.8 10.6 0.5 7.0 7.1 7.1 5.4 23.0 2.9 14.9 3.2 0.4 0.6 4.7 4.4 14.5 2.5 0.6 0.5 0.7 1.2 2.6 0.8 0.2 0.7 5.9 10.7 0.1 4.0 9.1 2.8 33.6 8.8 7.4 0.4 8.0 3.5 2.3 0.6 4.8 1.2 3.9 10.9 11.9 2.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 447.9 0.0 0.0 0.0 0.5 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21557.7 14.4 36.4 0.4 4.1 4.4 2.8 4.4 1.5 2645.6 3.1 2.3 3.4 17.2 14.6 11.0 361.0 2.8 132.1 0.4 0.4 0.5 0.8 0.4 0.6 0.6 0.5 0.7 0.4 0.6 0.5 1.6 6.4 33.1 0.3 5.5 37.7 0.1 0.0 0.6 0.0 0.6 1.8 0.6 0.0 1.8 0.0 0.0 0.0 76.8 0.0 0.0 0.0 0.3 0.1 0.0 3.4 0.0 37.8 0.0 0.0 0.1 4.2 0.0 0.1 270.7 0.0 0.0 0.0 6.4 0.0 0.1 0.0 0.0 4.0 1962.9 1.1 0.0 169.1 46.2 0.0 46.8 0.0 3.1 0.0 0.0 0.0 0.1 0.0 1.3 0.1 0.0 0.0 1.5 0.0 13.1 0.1 2.6 0.1 0.3 0.2 34.1 0.0 6.8 0.0 0.0 0.0 FGF22 ENSG00000070388 "Fibroblast growth factor 22" Q9HCT0 19 639879-644371 "Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.9;skin 1: 13.5" "Cell type enhanced" "Detected in some" "Bipolar cells: 8.4;Horizontal cells: 13.5;Muller glia cells: 4.7;Rod photoreceptor cells: 6.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "AN3-CA: 1.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted in other tissues" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 62: Horizontal cells - Visual perception" "unprognostic (1.58e-1)" "unprognostic (1.16e-1)" "unprognostic (2.84e-3)" "unprognostic (1.04e-2)" "unprognostic (1.17e-1)" "unprognostic (5.25e-4)" "unprognostic (1.16e-1)" "unprognostic (3.66e-3)" "unprognostic (2.85e-1)" "unprognostic (1.27e-2)" "unprognostic (1.10e-4)" "unprognostic (1.76e-1)" "unprognostic (1.70e-1)" "unprognostic (3.55e-2)" "unprognostic (2.91e-1)" "unprognostic (1.31e-1)" "unprognostic (8.36e-2)" 0.5 0.3 2.6 0.0 2.8 0.0 0.6 2.4 4.9 0.7 1.3 0.6 0.2 0.6 0.0 0.5 1.0 0.0 0.3 2.5 2.1 0.4 0.2 0.3 0.0 2.6 2.6 2.9 0.2 0.0 0.6 0.0 2.7 1.1 0.0 0.1 0.6 0.1 0.7 13.5 0.4 0.0 1.8 0.2 0.6 1.1 2.9 0.0 0.2 0.0 0.0 0.9 0.9 3.0 0.2 0.3 0.1 1.9 0.1 0.0 0.4 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.8 0.1 0.6 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.1 0.0 0.7 0.0 0.0 0.3 0.1 0.2 0.4 0.7 0.5 0.0 0.1 0.0 0.3 0.1 0.2 0.1 0.0 0.2 0.0 0.1 0.0 0.5 0.1 0.1 0.2 0.1 0.0 0.1 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 2.8 2.4 4.9 2.5 2.1 2.6 2.6 2.7 1.8 2.9 3.0 0.6 3.2 0.0 1.0 0.6 0.8 1.3 0.0 0.0 8.4 0.5 0.6 1.4 1.5 0.1 0.0 0.0 0.4 1.2 0.6 0.0 0.1 0.6 0.6 0.6 0.5 0.0 0.4 1.6 0.0 0.4 1.1 0.0 1.0 0.0 0.5 0.7 0.4 0.2 13.5 0.9 0.5 0.0 0.0 1.0 0.2 0.3 0.1 1.8 0.0 0.2 4.7 0.0 0.0 1.6 0.4 0.1 0.0 0.7 1.5 0.8 0.5 0.2 6.4 0.0 1.9 0.9 1.1 2.0 0.0 1.0 3.4 1.6 0.2 0.5 0.6 FLG2 IFPS ENSG00000143520 "Filaggrin family member 2" Q5D862 1 152348735-152360006 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "skin 1: 483.9" "Cell type enriched" "Detected in some" 11 "Suprabasal keratinocytes: 24.2" "Cancer enriched" "Detected in some" 8 "melanoma: 7.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA028699 Approved NA NA 21000000 "Cluster 61: Skin - Cornification" "Cluster 28: Keratinocytes - Keratinization" "HPA028699: AB_10601905" "unprognostic (2.58e-1)" "unprognostic (2.33e-1)" "unprognostic (3.08e-1)" "unprognostic (6.85e-2)" "unprognostic (6.59e-3)" "unprognostic (1.34e-1)" "unprognostic (2.25e-1)" "unprognostic (1.09e-1)" "unprognostic (2.08e-2)" "unprognostic (1.12e-1)" "unprognostic (1.96e-1)" 0.3 0.0 0.1 0.0 0.0 0.1 32.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.4 483.9 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.9 0.4 0.0 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.5 0.2 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.1 1.3 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 1.5 0.2 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 1.1 0.0 1.0 0.2 0.1 0.2 0.0 24.2 0.0 0.0 0.1 0.0 0.3 FOXA1 HNF3A ENSG00000129514 "Forkhead box A1" P55317 14 37589552-37596059 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 74.7;stomach 1: 28.0" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 113.8;Basal squamous epithelial cells: 76.8;Breast glandular cells: 87.9;Enteroendocrine cells: 84.6;Prostatic glandular cells: 89.8;Respiratory ciliated cells: 66.7;Urothelial cells: 154.5" "Group enriched" "Detected in many" 5 "breast cancer: 80.0;prostate cancer: 127.0" "Region enriched" "Detected in single" 5 "midbrain: 3.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 48.9;MCF7: 105.3;PC-3: 69.5;RT4: 96.7;SK-BR-3: 97.0;T-47d: 135.9" "Region enhanced" "Detected in some" "midbrain: 1.1" "Region enriched" "Detected in single" 6 "midbrain: 5.4" "CAB011595, HPA050505" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 35: Glandular cells - Unknown function" Nucleoplasm "Nucleoli fibrillar center" "CAB011595: AB_2104842, HPA050505: AB_2681148" "unprognostic (1.61e-1)" "unprognostic (8.80e-2)" "unprognostic (1.12e-1)" "unprognostic (4.65e-1)" "unprognostic (2.58e-1)" "unprognostic (1.51e-1)" "unprognostic (1.74e-1)" "unprognostic (1.78e-1)" "unprognostic (1.71e-1)" "unprognostic (3.01e-1)" "unprognostic (1.54e-2)" "unprognostic (6.30e-2)" "unprognostic (0.00e+0)" "unprognostic (3.67e-1)" "unprognostic (2.58e-1)" "unprognostic (1.69e-2)" "prognostic favorable (1.00e-4)" 0.2 0.1 0.0 1.6 0.0 0.0 22.3 0.0 0.0 1.5 0.0 12.4 8.4 0.1 0.6 11.9 2.4 2.3 0.0 0.0 0.3 0.1 26.9 7.5 0.0 0.1 3.5 0.0 0.5 0.0 0.7 0.0 0.2 74.7 10.4 0.0 19.3 0.3 0.0 1.3 4.8 0.2 0.2 0.0 28.0 0.4 0.7 0.0 0.0 0.0 2.3 20.5 4.4 0.0 4.9 4.4 0.0 2.8 0.0 0.0 0.5 0.0 0.4 0.0 0.0 21.3 2.7 0.0 1.4 0.0 0.1 23.4 13.2 3.3 0.1 0.0 23.4 0.0 4.1 48.9 0.0 0.0 0.2 0.0 0.7 0.0 0.4 1.9 0.0 0.4 0.9 0.0 0.0 105.3 0.1 0.3 0.0 32.0 69.5 0.0 1.1 0.4 9.9 96.7 11.8 0.0 4.8 97.0 0.0 0.0 135.9 0.4 0.0 0.9 0.1 0.4 3.2 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 3.5 0.2 0.2 0.7 0.0 0.3 28.9 43.5 0.0 0.1 1.0 113.8 47.8 76.8 0.0 87.9 34.8 1.3 30.0 52.3 3.7 0.0 0.0 0.5 27.5 0.0 1.5 0.4 2.7 0.2 1.2 84.6 0.0 0.0 2.4 0.0 1.0 35.7 4.4 2.5 0.0 1.1 31.7 0.0 0.0 0.0 34.9 42.7 0.9 0.3 0.9 0.0 0.7 3.6 0.0 1.0 0.0 0.0 0.0 0.0 4.3 27.2 0.0 1.2 89.8 4.9 0.0 66.7 0.0 0.0 0.0 2.3 0.9 1.2 62.9 0.1 0.0 1.4 0.1 27.9 154.5 FOXQ1 HFH1 ENSG00000164379 "Forkhead box Q1" Q9C009 6 1312098-1314758 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 107.2;urinary bladder: 53.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 60.4;Basal respiratory cells: 24.9;Collecting duct cells: 40.5;Gastric mucus-secreting cells: 67.2;Suprabasal keratinocytes: 45.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 39.0;HaCaT: 44.7;Hep G2: 93.8;OE19: 117.1;RT4: 38.2" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA059700 Supported Nucleoplasm Yes NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA059700: AB_2684107" "unprognostic (2.04e-3)" "unprognostic (3.44e-1)" "unprognostic (1.10e-1)" "unprognostic (7.18e-2)" "unprognostic (1.50e-3)" "unprognostic (2.15e-1)" "unprognostic (3.26e-2)" "unprognostic (1.15e-3)" "unprognostic (1.04e-2)" "unprognostic (1.06e-1)" "unprognostic (7.65e-3)" "prognostic favorable (6.68e-4)" "unprognostic (1.49e-2)" "unprognostic (3.16e-3)" "unprognostic (2.82e-1)" "unprognostic (3.93e-2)" "unprognostic (1.96e-2)" 0.3 0.0 6.9 0.2 5.2 0.0 1.4 7.1 7.1 6.7 3.8 0.8 10.4 0.9 0.3 11.3 3.9 5.4 0.0 4.7 5.1 9.8 6.4 4.0 0.0 5.6 6.0 0.0 6.5 0.1 2.5 1.1 6.0 8.9 0.4 0.1 30.4 1.1 0.2 25.7 0.6 0.0 5.3 0.0 107.2 0.2 7.5 0.6 3.6 0.6 8.0 53.5 16.9 4.7 16.0 1.4 0.0 0.0 0.0 0.0 0.0 0.7 13.5 0.1 0.1 39.0 22.6 0.0 0.7 0.0 0.1 44.7 0.0 1.7 0.0 0.0 1.1 0.0 8.2 93.8 0.0 0.0 2.4 0.0 16.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 117.1 0.8 0.0 0.0 0.0 0.4 38.2 0.3 0.0 3.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 15.5 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 5.2 7.1 7.1 4.7 5.1 5.6 6.0 6.0 5.3 7.5 4.7 0.3 16.0 10.6 0.0 0.0 60.4 3.2 24.9 6.8 0.0 5.3 5.1 0.8 0.0 16.8 40.5 0.0 0.0 0.0 0.0 1.9 3.0 0.0 5.2 3.0 0.4 0.0 0.0 1.2 13.4 0.0 1.4 67.2 14.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.1 0.0 2.9 0.0 0.0 0.7 1.8 15.9 0.0 0.0 0.0 0.0 0.5 11.8 0.0 0.0 0.2 0.6 0.0 6.2 5.0 0.0 0.0 0.0 1.6 0.0 0.0 22.2 45.5 0.0 0.3 0.0 0.0 3.9 FUT9 Fuc-TIX ENSG00000172461 "Fucosyltransferase 9" Q9Y231 6 96015974-96215612 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 18.9;stomach 1: 23.2" "Cell type enhanced" "Detected in some" "Astrocytes: 776.4;Excitatory neurons: 333.5;Inhibitory neurons: 238.2;Oligodendrocyte precursor cells: 168.9;Oligodendrocytes: 224.7" "Cancer enhanced" "Detected in some" "glioma: 1.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MCF7: 2.9;OE19: 2.8;RT4: 6.5;SCLC-21H: 6.3;SK-BR-3: 3.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070923 Approved "Nucleoplasm,Microtubules,Cytokinetic bridge,Cytosol" Yes No "Cluster 22: Non-specific - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "Microtubules, Cytokinetic bridge, Cytosol" "HPA070923: AB_2686323" "unprognostic (1.60e-1)" "unprognostic (2.48e-1)" "unprognostic (5.99e-3)" "unprognostic (1.33e-1)" "unprognostic (2.40e-1)" "unprognostic (2.97e-1)" "unprognostic (1.35e-1)" "unprognostic (2.85e-1)" "unprognostic (1.45e-1)" "unprognostic (1.12e-1)" "unprognostic (6.43e-3)" "unprognostic (5.60e-2)" "unprognostic (1.65e-2)" "unprognostic (3.03e-2)" 0.0 0.4 10.5 0.0 12.6 0.0 0.6 14.5 11.7 0.0 0.0 0.1 2.1 0.2 0.0 0.0 0.2 0.0 0.0 11.8 13.6 0.2 0.0 0.0 0.0 3.4 18.9 0.0 4.8 0.0 0.4 0.4 3.2 0.2 0.0 0.5 0.0 0.2 0.1 0.1 0.0 0.0 5.5 0.0 23.2 0.0 15.3 0.0 0.1 0.0 0.0 0.9 0.0 6.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 1.4 2.8 0.0 0.0 0.0 0.0 0.0 6.5 6.3 0.1 0.0 3.6 0.0 0.1 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 12.6 14.5 11.7 11.8 13.6 3.4 18.9 3.2 5.5 15.3 6.4 0.0 0.0 0.0 776.4 0.2 0.0 0.6 0.0 0.0 4.2 1.4 1.7 0.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.3 0.5 0.1 1.3 0.0 0.0 333.5 2.0 0.0 0.1 56.1 1.4 0.0 0.4 0.0 0.0 0.1 0.0 238.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.1 0.0 0.2 0.0 168.9 224.7 0.5 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.2 GABRA4 ENSG00000109158 "Gamma-aminobutyric acid type A receptor subunit alpha4" P48169 4 46918900-46993581 "FDA approved drug targets, Predicted membrane proteins" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 7.5;heart muscle: 2.5" "Group enriched" "Detected in some" 6 "Excitatory neurons: 124.9;Inhibitory neurons: 160.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 149 "REH: 14.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 14: REH - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (2.78e-2)" "unprognostic (6.57e-3)" "unprognostic (2.46e-1)" "unprognostic (2.23e-1)" "unprognostic (3.17e-1)" "unprognostic (1.11e-1)" "unprognostic (6.91e-2)" 0.0 0.0 1.8 0.0 7.5 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 2.5 4.0 2.6 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 7.5 0.0 6.8 4.0 2.6 0.7 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 21.5 0.0 0.5 0.0 0.0 0.6 0.3 0.0 0.6 15.8 0.0 0.0 0.0 0.0 0.2 0.0 0.2 1.9 0.0 1.3 0.0 0.0 0.1 0.0 0.0 124.9 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 160.1 0.4 0.0 0.0 0.0 0.3 0.0 0.1 0.0 8.4 0.0 6.1 0.0 3.5 3.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 1.4 3.8 0.1 0.4 0.1 0.0 0.0 0.0 0.9 0.0 GAL "GAL-GMAP, GALN, GLNN, GMAP" ENSG00000069482 "Galanin and GMAP prepropeptide" P22466 11 68683779-68691175 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Hormone, Neuropeptide" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 23 "brain: 645.9;pituitary gland: 885.8" "Group enriched" "Detected in many" 4 "Basal prostatic cells: 22.2;Ductal cells: 38.9;Endometrial ciliated cells: 64.2;Endometrial stromal cells: 50.8;Exocrine glandular cells: 52.1;Extravillous trophoblasts: 48.7;Glandular and luminal cells: 26.4;Pancreatic endocrine cells: 39.5;Prostatic glandular cells: 82.5;Urothelial cells: 24.3" "Cancer enhanced" "Detected in many" "testis cancer: 22.2" "Region enriched" "Detected in many" 13 "hypothalamus: 645.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 267.2;HEK 293: 119.3;K-562: 139.5;NB-4: 493.5;SH-SY5Y: 189.6" "Region enhanced" "Detected in many" "hypothalamus: 82.6" "Low region specificity" "Detected in all" "HPA049864, CAB079779" Enhanced Supported Supported "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 60000 200000 "Cluster 7: Monocytes - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 24: NB-4 - Immune response" "Cluster 36: Stromal cells - Cell proliferation" "Golgi apparatus" Vesicles "CAB079779: , HPA049864: AB_2680922" "unprognostic (8.56e-2)" "unprognostic (1.45e-2)" "unprognostic (7.50e-2)" "prognostic unfavorable (1.22e-4)" "unprognostic (2.70e-1)" "unprognostic (2.27e-2)" "unprognostic (8.07e-3)" "prognostic unfavorable (8.17e-4)" "unprognostic (5.98e-2)" "unprognostic (1.07e-2)" "unprognostic (8.84e-2)" "unprognostic (7.42e-2)" "unprognostic (1.20e-1)" "unprognostic (8.85e-2)" "unprognostic (7.88e-2)" "unprognostic (5.38e-2)" "unprognostic (3.24e-2)" 3.2 0.9 2.8 14.9 2.1 0.7 4.4 1.1 5.2 1.0 0.8 17.6 1.8 0.2 0.0 0.8 1.0 0.2 1.0 2.2 645.9 1.5 0.3 0.5 0.1 48.5 5.1 0.2 2.1 0.1 885.8 0.3 13.8 4.4 4.0 0.0 0.9 0.2 0.4 33.3 4.1 9.9 0.6 0.3 9.7 1.0 19.5 0.7 0.4 0.0 0.0 0.7 2.9 2.6 0.0 11.0 1.1 0.3 0.0 0.0 24.0 36.7 0.0 0.7 0.0 267.2 9.9 0.0 12.7 1.3 0.4 0.1 0.0 0.2 0.0 0.0 119.3 6.4 74.6 0.0 1.3 3.7 0.0 1.7 4.0 0.0 0.1 0.0 6.3 0.0 139.5 0.0 0.2 77.2 0.0 493.5 60.3 2.9 23.7 0.0 0.1 51.1 0.6 0.0 49.8 189.6 25.8 1.5 0.0 26.8 1.5 57.6 0.0 0.0 0.0 0.3 2.9 0.0 0.0 0.1 0.0 0.4 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 2.1 1.1 5.2 2.2 645.9 48.5 5.1 13.8 0.6 19.5 2.6 0.6 0.0 0.0 0.0 0.2 2.0 22.2 0.1 0.0 0.0 3.2 5.8 1.4 0.0 0.0 0.0 0.0 0.6 0.1 0.7 0.0 38.9 0.1 64.2 50.8 3.4 1.8 4.2 2.1 52.1 48.7 6.6 2.0 26.4 4.5 0.4 0.0 0.0 2.0 0.0 0.2 1.1 4.1 0.0 1.2 0.2 0.0 0.7 1.8 0.0 0.6 0.0 0.0 0.0 0.3 39.5 0.1 0.0 1.0 82.5 0.0 0.4 0.0 0.0 0.0 1.6 6.7 2.2 10.9 1.1 3.4 1.9 0.8 0.0 1.3 24.3 GAL3ST4 FLJ12116 ENSG00000197093 "Galactose-3-O-sulfotransferase 4" Q96RP7 7 100159244-100168617 "Metabolic proteins, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 27.7" "Cell type enhanced" "Detected in many" "Hofbauer cells: 37.2;Microglial cells: 23.4;Oligodendrocyte precursor cells: 24.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "memory CD4 T-cell: 4.5;naive CD4 T-cell: 15.0;naive CD8 T-cell: 4.6;plasmacytoid DC: 4.7" "Group enriched" "Detected in many" 29 "dendritic cells: 4.7;T-cells: 15.0" "Cell line enhanced" "Detected in many" "WM-115: 43.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038137, HPA038138" Uncertain Approved Nucleoplasm,Cytosol NA NA 35000 "Cluster 32: T-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm Cytosol "HPA038137: AB_10697239, HPA038138: AB_2675854" "unprognostic (4.22e-2)" "unprognostic (2.97e-2)" "prognostic unfavorable (5.44e-4)" "unprognostic (8.64e-2)" "unprognostic (3.01e-2)" "unprognostic (1.40e-1)" "unprognostic (3.10e-2)" "unprognostic (1.81e-1)" "unprognostic (1.31e-1)" "prognostic unfavorable (2.57e-4)" "unprognostic (2.80e-1)" "unprognostic (2.25e-1)" "prognostic unfavorable (4.14e-4)" "unprognostic (3.98e-2)" "unprognostic (9.67e-2)" "unprognostic (1.89e-2)" "unprognostic (5.36e-2)" 4.3 4.9 9.2 3.9 9.3 0.7 3.7 8.4 12.6 11.0 7.6 6.1 3.8 9.1 3.1 7.8 6.0 5.6 5.0 9.1 9.5 1.4 0.9 5.2 2.9 13.4 9.5 6.3 1.4 3.0 4.2 5.1 10.1 4.8 6.3 0.5 25.6 3.6 1.9 27.7 5.0 9.9 10.7 2.7 2.4 4.8 15.9 22.3 1.9 1.9 3.2 6.7 10.6 13.1 0.1 0.9 5.4 2.3 4.7 9.6 10.9 3.2 3.2 1.8 2.6 0.6 0.2 1.1 0.7 10.4 3.3 12.2 0.3 1.8 0.6 0.1 0.6 0.4 0.2 0.4 3.4 0.3 2.7 11.7 4.6 5.5 0.6 4.0 3.7 4.3 1.6 0.2 3.4 0.4 4.2 0.2 1.9 11.5 1.3 2.7 2.4 0.2 0.0 0.4 0.3 2.2 1.0 0.0 6.7 1.0 0.0 0.3 3.4 0.3 1.6 0.5 0.1 0.2 0.2 2.5 1.9 0.4 43.3 0.0 0.1 0.0 0.5 0.0 0.0 0.1 4.5 0.3 0.0 0.1 15.0 4.6 0.3 0.2 0.1 4.7 1.3 2.2 9.2 9.3 8.4 12.6 9.1 9.5 13.4 9.5 10.1 10.7 15.9 13.1 0.7 0.0 0.5 2.9 0.1 4.2 2.0 3.3 7.4 0.0 2.2 2.4 1.0 1.5 0.9 0.0 0.0 0.3 0.3 1.5 0.0 0.6 0.2 0.2 2.1 1.2 0.0 2.7 0.5 0.0 0.4 7.5 0.0 0.3 0.0 1.2 1.4 0.0 37.2 0.0 0.3 1.3 4.1 1.3 0.8 0.0 4.7 9.6 5.4 23.4 0.7 0.4 0.0 24.6 0.5 0.3 2.5 5.3 0.0 0.5 0.0 0.0 0.1 0.1 0.0 3.7 3.3 0.6 0.3 4.2 8.1 0.8 0.7 0.1 4.1 1.4 GAS7 "KIAA0394, MGC1348" ENSG00000007237 "Growth arrest specific 7" O60861 17 9910606-10198606 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 85.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 133.6;Fibroblasts: 79.6;Inhibitory neurons: 76.6;Late spermatids: 73.4;Oligodendrocytes: 163.3" "Group enriched" "Detected in all" 4 "glioma: 15.7;melanoma: 54.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 26.2" "Group enriched" "Detected in many" 4 "granulocytes: 17.1;monocytes: 26.2" "Cell line enriched" "Detected in many" 9 "WM-115: 533.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004838, HPA064678" Enhanced Approved "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 6: Brain - Smell perception" "Cluster 17: WM-115 - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Actin filaments, Focal adhesion sites" "HPA004838: AB_2667263, HPA064678: AB_2685319" "unprognostic (1.68e-2)" "unprognostic (2.84e-3)" "unprognostic (1.80e-1)" "unprognostic (1.28e-3)" "unprognostic (1.15e-1)" "unprognostic (1.01e-2)" "unprognostic (7.32e-2)" "unprognostic (7.16e-2)" "unprognostic (2.88e-1)" "unprognostic (1.50e-2)" "unprognostic (2.48e-1)" "unprognostic (1.79e-1)" "unprognostic (1.94e-3)" "unprognostic (6.48e-2)" "unprognostic (8.78e-2)" "unprognostic (3.08e-2)" "prognostic unfavorable (6.89e-4)" 27.3 8.5 34.9 23.7 68.9 31.1 15.3 75.4 79.8 29.9 0.0 26.3 7.3 13.3 4.3 23.8 17.8 16.3 46.1 61.9 8.4 1.7 2.3 17.1 9.1 23.4 24.1 7.8 3.4 1.1 2.6 16.2 15.8 8.5 12.0 30.1 7.8 10.8 5.8 33.7 11.9 24.0 14.3 16.1 8.9 17.4 32.9 9.3 4.6 6.8 10.3 18.3 19.5 85.3 0.1 0.5 0.6 1.0 16.5 22.5 0.3 0.8 0.0 2.6 1.1 0.1 0.2 6.6 1.9 6.6 0.3 0.3 0.0 0.0 1.6 0.0 1.5 0.0 1.3 0.7 5.3 1.8 48.7 4.3 0.3 5.1 0.1 0.0 0.0 42.7 0.0 0.6 0.0 0.0 54.3 15.4 2.6 2.1 0.0 14.3 0.1 49.6 0.0 0.2 0.1 3.0 0.2 0.2 60.1 21.0 2.8 24.7 0.0 0.2 3.4 0.1 0.1 0.4 0.0 0.0 0.4 35.1 533.8 0.6 26.2 17.1 2.8 6.9 0.9 0.5 0.3 1.4 5.3 0.6 0.2 1.4 16.4 4.5 4.9 1.0 0.0 7.7 34.9 68.9 75.4 79.8 61.9 8.4 23.4 24.1 15.8 14.3 32.9 85.3 2.9 0.0 4.2 6.8 3.3 8.3 4.5 1.5 1.2 34.6 1.6 2.3 13.3 0.0 1.1 5.5 27.1 1.0 14.5 0.0 0.0 1.0 62.3 17.7 12.8 5.7 0.0 0.4 133.6 0.0 1.8 79.6 0.0 26.3 17.2 7.9 5.0 0.9 39.2 0.0 76.6 0.0 0.0 66.7 32.2 73.4 10.2 54.3 33.8 52.5 57.2 9.5 18.6 11.1 163.3 0.2 0.0 1.9 5.5 2.0 0.0 0.1 16.3 31.7 0.0 67.0 7.1 1.6 6.7 1.0 16.6 1.9 7.4 0.2 0.0 4.9 GATA3 HDR ENSG00000107485 "GATA binding protein 3" P23771 10 8045378-8075198 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Immunity, Innate immunity, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 109.9;skin 1: 172.9" "Cell type enhanced" "Detected in many" "Breast glandular cells: 267.1;Cytotrophoblasts: 323.5;Extravillous trophoblasts: 746.6;Suprabasal keratinocytes: 198.9;Syncytiotrophoblasts: 1134.9" "Group enriched" "Detected in many" 24 "breast cancer: 190.0;urothelial cancer: 87.0" "Group enriched" "Detected in many" 5 "midbrain: 28.3;pons: 12.6" "Group enriched" "Detected in many" 41 "gdT-cell: 19.9;MAIT T-cell: 26.9;memory CD4 T-cell: 36.7;memory CD8 T-cell: 28.8;naive CD4 T-cell: 19.9;naive CD8 T-cell: 18.3;NK-cell: 36.1;T-reg: 43.6" "Group enriched" "Detected in many" 57 "NK-cells: 36.1;T-cells: 43.6" "Cell line enhanced" "Detected in many" "BEWO: 190.2;MCF7: 473.4;RT4: 194.3;SH-SY5Y: 161.2;T-47d: 605.2" "Region enriched" "Detected in single" 6 "midbrain: 6.1" "Group enriched" "Detected in some" 11 "medulla oblongata: 5.2;midbrain: 14.0;pons: 11.8;thalamus: 13.1" "CAB016217, HPA029730" Enhanced Supported Nucleoplasm NA NA "Cluster 35: T-regs - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 6: T47d - Mammary gland" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm "CAB016217: AB_2108591, HPA029730: AB_10601907" "unprognostic (1.70e-1)" "unprognostic (7.23e-2)" "unprognostic (3.58e-2)" "unprognostic (2.00e-1)" "unprognostic (7.03e-3)" "unprognostic (4.68e-3)" "unprognostic (4.23e-2)" "unprognostic (9.65e-2)" "unprognostic (2.06e-1)" "unprognostic (2.55e-1)" "unprognostic (3.83e-1)" "unprognostic (1.17e-1)" "prognostic unfavorable (3.13e-4)" "unprognostic (1.48e-1)" "unprognostic (5.16e-2)" "unprognostic (6.31e-2)" "unprognostic (1.82e-3)" 6.7 6.4 0.9 3.8 0.2 4.1 34.2 0.2 0.2 3.4 0.8 0.7 1.0 0.6 8.6 0.6 0.5 1.2 2.5 0.1 0.6 24.9 1.0 3.4 7.8 3.9 28.3 0.1 0.3 109.9 5.0 32.2 12.6 11.2 0.7 0.0 19.9 24.9 2.1 172.9 2.4 0.3 0.5 7.2 1.5 0.2 4.1 25.0 3.0 1.0 3.8 38.8 10.8 0.2 33.8 8.1 0.0 0.4 0.0 0.0 190.2 0.7 0.0 0.0 0.1 12.4 29.9 0.0 0.1 0.0 0.0 28.9 3.2 0.6 0.1 95.8 10.2 0.2 0.3 0.1 2.1 0.1 0.5 0.0 6.9 0.1 1.8 1.0 15.3 45.8 0.4 0.0 0.1 473.4 54.2 0.5 3.5 6.5 4.5 2.8 2.6 0.8 0.0 194.3 9.8 161.2 0.5 26.8 0.0 34.1 605.2 0.1 0.0 2.4 5.9 1.4 4.3 0.9 0.0 0.0 1.3 0.0 1.7 0.1 0.1 0.0 19.9 0.0 26.9 0.4 36.7 28.8 0.0 0.1 19.9 18.3 0.7 36.1 0.0 0.0 43.6 7.0 0.9 0.2 0.2 0.2 0.1 0.6 3.9 28.3 12.6 0.5 4.1 0.2 14.6 0.0 6.0 0.0 3.4 94.8 69.6 1.6 0.0 0.0 267.1 167.3 1.3 0.0 1.5 178.4 0.0 323.5 49.2 0.0 0.0 0.2 0.2 0.5 0.4 12.6 0.0 2.1 0.0 0.4 746.6 5.3 2.6 0.7 2.5 0.0 6.8 0.6 30.7 0.0 0.0 0.0 0.0 3.5 9.9 0.1 0.0 3.8 8.8 1.0 1.5 0.0 51.5 0.0 0.0 4.1 1.1 0.0 12.2 45.8 0.0 0.6 0.3 0.0 0.0 1.1 2.8 0.0 1.4 1.0 198.9 1134.9 93.4 0.5 0.0 106.1 GDPD2 "FLJ20207, GDE3, OBDPF" ENSG00000130055 "Glycerophosphodiester phosphodiesterase domain containing 2" Q9HCC8 X 70423031-70433390 "Enzymes, Metabolic proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 20.8;lymphoid tissue: 59.2;skin 1: 47.8" "Group enriched" "Detected in some" 4 "Basal keratinocytes: 56.7;Distal enterocytes: 30.4;Muller glia cells: 29.9;Proximal enterocytes: 92.2" "Cancer enhanced" "Detected in many" "glioma: 10.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "AF22: 9.2;NTERA-2: 19.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 45: Enterocytes - Digestion" "unprognostic (1.53e-3)" "unprognostic (5.79e-2)" "unprognostic (5.37e-2)" "unprognostic (5.00e-7)" "unprognostic (3.15e-3)" "unprognostic (3.65e-2)" "unprognostic (2.86e-2)" "unprognostic (4.66e-2)" "unprognostic (1.19e-1)" "unprognostic (8.40e-2)" "unprognostic (8.45e-2)" "unprognostic (1.06e-1)" "unprognostic (1.35e-2)" "unprognostic (5.41e-2)" "unprognostic (5.52e-2)" "unprognostic (2.22e-1)" "unprognostic (8.91e-2)" 0.0 0.0 10.4 0.5 9.8 0.1 0.9 7.6 10.3 0.0 8.9 4.8 11.1 0.0 4.9 0.2 0.2 0.2 0.7 8.5 11.0 0.5 0.0 0.0 0.0 9.4 14.4 0.1 0.0 0.0 3.2 0.1 10.4 0.0 3.9 3.6 1.0 0.3 0.5 47.8 20.8 0.1 9.0 59.2 1.8 0.0 12.4 0.0 0.0 0.0 0.0 0.7 0.1 10.8 0.0 0.0 9.2 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 2.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.2 19.8 0.7 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.6 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 10.4 9.8 7.6 10.3 8.5 11.0 9.4 14.4 10.4 9.0 12.4 10.8 0.0 0.0 0.0 12.7 0.0 56.7 0.0 0.6 0.0 0.2 0.0 0.0 1.9 0.0 0.2 0.0 0.0 7.0 0.0 30.4 0.0 0.0 0.0 0.3 0.0 0.2 1.2 0.0 0.0 0.0 3.5 0.2 3.1 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.1 3.7 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 29.9 0.0 0.0 0.1 0.1 2.3 0.0 0.0 0.0 92.2 0.0 0.1 0.9 0.0 0.0 0.1 0.0 0.0 0.0 12.1 3.3 0.2 0.0 3.1 0.2 GLDC "GCSP, NKH" ENSG00000178445 "Glycine decarboxylase" P23378 9 6532467-6645729 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 173.5" "Cell type enhanced" "Detected in many" "Collecting duct cells: 31.3;Cytotrophoblasts: 79.0;Extravillous trophoblasts: 41.6;Hepatocytes: 120.5;Oligodendrocyte precursor cells: 52.3;Proximal tubular cells: 31.6;Syncytiotrophoblasts: 46.0" "Cancer enhanced" "Detected in many" "testis cancer: 41.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 235.7;CACO-2: 58.2;HMC-1: 45.6;RPTEC TERT1: 95.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002318, HPA052887" Enhanced Supported Nucleoplasm,Mitochondria NA NA 740000 "Cluster 37: B-cells - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria Nucleoplasm "HPA002318: AB_1849700, HPA052887: AB_2681980" "unprognostic (6.73e-2)" "unprognostic (1.19e-1)" "unprognostic (6.50e-2)" "prognostic unfavorable (5.24e-5)" "unprognostic (1.50e-1)" "unprognostic (7.87e-2)" "unprognostic (1.81e-1)" "unprognostic (1.50e-1)" "unprognostic (2.40e-1)" "unprognostic (1.74e-1)" "unprognostic (2.47e-2)" "unprognostic (2.69e-1)" "prognostic favorable (3.50e-4)" "unprognostic (1.65e-2)" "unprognostic (1.27e-1)" "unprognostic (5.62e-3)" "unprognostic (1.17e-2)" 0.3 0.3 15.3 1.4 15.5 0.5 0.8 14.7 23.7 0.4 12.9 1.0 0.8 0.4 5.2 3.2 0.7 0.8 0.1 14.8 14.4 38.2 173.5 1.0 1.6 14.0 13.6 0.3 0.1 0.0 4.9 15.2 13.4 0.5 0.4 1.6 1.1 1.0 1.3 4.5 0.8 0.0 13.1 1.2 1.0 3.5 15.8 0.0 5.1 0.1 1.2 1.1 0.1 15.3 0.6 4.9 2.1 25.6 0.2 0.4 235.7 0.1 0.0 0.0 0.1 58.2 0.5 0.3 5.6 0.1 0.7 0.4 0.0 0.7 0.2 1.2 13.4 0.2 0.3 38.3 0.0 0.1 45.6 0.0 0.1 1.8 0.3 1.0 9.0 4.3 0.0 0.5 1.2 1.5 0.9 0.2 27.5 4.6 3.8 1.3 0.0 0.5 95.4 1.0 22.6 11.7 0.0 21.4 0.3 13.9 5.3 0.1 3.0 0.6 0.6 2.6 1.3 1.1 34.4 0.1 0.8 2.4 5.1 0.4 0.1 0.1 0.1 0.0 0.1 0.8 0.1 0.0 0.0 0.1 0.0 0.1 0.4 0.1 0.1 0.1 0.0 0.3 15.3 15.5 14.7 23.7 14.8 14.4 14.0 13.6 13.4 13.1 15.8 15.3 0.2 0.0 0.0 17.6 1.9 0.0 0.0 0.2 1.2 0.4 1.5 0.6 0.7 11.5 0.1 31.3 0.0 79.0 0.2 0.0 5.9 0.0 12.6 5.4 0.5 0.6 0.0 0.0 21.6 0.2 41.6 0.3 0.0 10.7 0.0 1.1 2.2 120.5 7.0 0.0 15.9 0.0 0.0 2.8 0.3 10.8 0.3 0.4 0.0 1.9 0.0 9.6 0.0 52.3 1.8 0.1 0.0 0.0 15.1 0.0 0.0 31.6 0.0 0.4 0.0 1.7 0.8 4.5 5.1 0.4 0.0 46.0 0.8 0.0 0.0 0.1 GPR143 OA1 ENSG00000101850 "G protein-coupled receptor 143" P51810 X 9725346-9786297 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Albinism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 14.2;choroid plexus: 14.4" "Group enriched" "Detected in many" 8 "Cytotrophoblasts: 40.6;Melanocytes: 126.3" "Cancer enriched" "Detected in all" 9 "melanoma: 84.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "basophil: 3.1" "Lineage enriched" "Detected in single" 19 "granulocytes: 3.1" "Cell line enriched" "Detected in some" 7 "SK-MEL-30: 159.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA003648 Enhanced NA NA "Cluster 34: Basophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 47: Cytotrophoblasts - Unknown function" "HPA003648: AB_2667028" "unprognostic (4.60e-2)" "prognostic favorable (8.73e-4)" "unprognostic (7.43e-3)" "unprognostic (5.41e-2)" "unprognostic (4.62e-3)" "unprognostic (2.00e-2)" "unprognostic (3.05e-1)" "unprognostic (2.64e-3)" "unprognostic (3.78e-1)" "unprognostic (5.89e-2)" "unprognostic (8.18e-2)" "unprognostic (8.40e-2)" "prognostic favorable (2.45e-5)" "unprognostic (2.75e-1)" "unprognostic (2.07e-1)" "unprognostic (8.76e-2)" "unprognostic (1.59e-2)" 0.6 1.1 10.6 0.1 13.0 0.0 1.7 11.8 11.5 2.0 14.4 1.4 0.5 3.2 5.3 2.4 2.8 0.9 0.1 10.8 13.1 4.6 1.7 1.0 0.5 12.6 14.2 3.3 1.2 2.9 2.7 6.1 12.3 2.6 1.4 0.9 3.3 4.4 0.0 8.9 0.5 1.0 11.4 0.0 0.7 0.8 13.1 1.8 3.2 0.0 1.6 1.1 1.1 12.2 1.9 0.4 4.6 0.2 0.0 0.0 3.7 0.0 0.0 0.0 0.0 2.1 0.1 0.0 0.2 0.0 0.4 0.1 0.2 1.1 0.1 0.1 0.3 0.0 0.2 0.6 2.3 0.0 3.4 0.1 1.6 0.0 0.0 24.2 6.7 0.0 0.0 0.0 0.0 12.1 0.0 0.1 11.1 0.0 0.1 0.0 0.1 0.1 22.2 3.2 0.9 0.0 0.3 0.0 159.6 10.8 1.9 0.0 4.6 0.0 0.2 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.4 3.1 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 10.6 13.0 11.8 11.5 10.8 13.1 12.6 14.2 12.3 11.4 13.1 12.2 0.1 0.0 0.0 9.8 0.2 5.5 1.3 1.8 2.2 0.5 2.1 1.7 0.9 0.0 4.9 7.3 0.0 40.6 0.0 0.8 1.9 4.9 0.2 1.7 1.6 1.5 0.0 0.0 0.6 0.6 2.1 1.0 0.0 1.3 0.0 1.8 2.9 0.3 4.8 0.0 0.3 0.8 2.0 0.0 1.6 1.8 1.8 0.1 126.3 1.0 0.0 1.2 0.0 0.5 0.6 1.2 0.2 6.4 0.0 1.8 0.2 5.0 3.2 0.2 0.0 0.0 0.7 0.2 1.3 4.2 0.6 10.1 0.7 1.0 2.0 1.8 GRB14 ENSG00000115290 "Growth factor receptor bound protein 14" Q14449 2 164492417-164621482 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 12.6;tongue: 20.3" "Group enriched" "Detected in many" 4 "Distal tubular cells: 92.0;Granulosa cells: 272.4" "Cancer enhanced" "Detected in many" "liver cancer: 9.5" "Region enhanced" "Detected in single" "hippocampal formation: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 5.5;HUVEC TERT2: 9.6;RPTEC TERT1: 9.1;TIME: 11.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB022294, HPA035052, HPA035053" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 8: Non-specific - Mitochondria" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Cytosol" "CAB022294: , HPA035052: , HPA035053: AB_2674432" "unprognostic (2.60e-1)" "unprognostic (6.34e-2)" "unprognostic (1.74e-2)" "unprognostic (6.75e-2)" "unprognostic (7.47e-2)" "unprognostic (8.33e-5)" "unprognostic (5.00e-2)" "unprognostic (3.55e-1)" "unprognostic (2.47e-2)" "unprognostic (2.33e-1)" "unprognostic (5.71e-2)" "unprognostic (8.33e-3)" "unprognostic (2.71e-1)" "unprognostic (1.89e-3)" "unprognostic (7.10e-2)" "unprognostic (5.19e-2)" "unprognostic (9.27e-2)" 0.7 3.0 0.0 0.3 0.4 0.0 0.3 0.0 0.6 0.1 0.1 0.9 0.9 0.2 5.4 1.2 0.1 0.1 2.7 1.3 0.1 6.6 12.6 0.4 0.0 0.3 0.2 2.0 4.7 0.0 0.3 1.7 0.0 0.3 0.3 0.4 0.3 0.3 2.4 0.2 0.2 0.4 0.0 0.2 0.2 2.6 0.3 0.0 0.9 20.3 0.0 0.0 0.1 0.0 0.8 5.5 0.3 0.0 0.8 0.0 0.0 0.4 0.0 0.0 0.0 2.5 0.5 0.0 2.9 0.0 0.9 0.3 0.8 1.2 0.3 0.0 4.1 0.0 0.3 1.3 0.1 0.0 0.0 0.3 0.8 1.8 0.0 1.6 9.6 0.0 0.0 0.0 1.5 2.1 0.0 0.0 1.9 0.2 1.2 0.0 0.0 0.1 9.1 0.4 3.1 0.3 0.0 0.3 0.0 1.1 0.7 0.0 11.8 0.1 1.2 0.0 0.1 0.4 0.1 0.0 2.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.4 0.0 0.6 1.3 0.1 0.3 0.2 0.0 0.0 0.3 0.0 4.5 0.0 5.4 0.7 0.1 0.1 0.3 0.0 0.0 1.3 1.6 1.4 17.7 22.8 0.0 16.5 0.0 0.2 1.3 0.3 92.0 13.5 1.5 0.6 0.2 3.0 0.0 0.0 24.5 3.3 0.2 2.4 0.0 1.9 0.0 272.4 1.1 40.4 0.0 0.0 6.2 2.6 0.0 1.0 0.3 4.4 9.3 3.2 19.6 1.9 1.0 0.3 0.0 3.5 2.3 4.0 0.0 17.3 0.0 0.8 0.3 14.7 0.0 0.8 13.1 0.8 10.9 0.7 6.4 0.1 0.0 0.1 0.2 30.4 1.6 0.2 GRIA2 "GluA2, GLUR2, GLURB" ENSG00000120251 "Glutamate ionotropic receptor AMPA type subunit 2" P42262 4 157204182-157366075 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Autism spectrum disorder, Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 78.4;retina: 29.0" "Cell type enhanced" "Detected in some" "Astrocytes: 335.0;Bipolar cells: 252.7;Excitatory neurons: 1090.5;Inhibitory neurons: 725.5;Oligodendrocyte precursor cells: 1106.8;Oligodendrocytes: 324.7" "Group enriched" "Detected in some" 10 "breast cancer: 2.7;endometrial cancer: 2.6;glioma: 6.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "SCLC-21H: 16.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008441 Enhanced NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA008441: AB_1078983" "unprognostic (1.36e-1)" "unprognostic (9.60e-3)" "unprognostic (4.15e-2)" "unprognostic (1.17e-1)" "unprognostic (1.02e-1)" "unprognostic (8.70e-2)" "unprognostic (3.87e-1)" "unprognostic (1.53e-1)" "unprognostic (3.92e-3)" "unprognostic (7.40e-2)" "unprognostic (2.91e-5)" "unprognostic (2.42e-1)" "unprognostic (1.31e-1)" "unprognostic (1.82e-1)" "unprognostic (6.55e-2)" 0.3 6.9 32.8 0.2 60.2 0.0 1.1 11.4 77.4 9.2 0.0 0.2 0.1 17.0 11.5 0.1 11.0 0.0 0.1 78.4 11.3 0.4 0.0 0.2 0.0 0.0 7.4 0.6 1.4 0.0 21.7 0.1 0.0 0.8 0.1 29.0 4.1 2.3 0.2 1.6 0.1 6.2 1.4 0.2 1.2 1.4 37.3 0.1 0.0 0.6 0.0 0.1 0.4 43.2 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.9 2.3 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.9 0.1 0.0 0.0 0.5 0.0 0.0 0.6 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.8 60.2 11.4 77.4 78.4 11.3 0.0 7.4 0.0 1.4 37.3 43.2 0.0 0.0 0.0 335.0 0.0 0.0 0.0 0.0 0.0 252.7 2.1 1.0 2.3 0.0 0.0 0.0 43.8 0.0 0.1 0.0 0.0 0.0 0.1 1.7 1.1 0.3 0.0 0.0 1090.5 0.0 0.0 0.2 0.0 2.7 0.0 0.1 0.0 0.0 0.1 138.0 725.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.8 58.1 0.0 4.2 0.0 1106.8 324.7 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 16.5 0.0 0.0 0.5 3.8 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 GSDMA "FLJ39120, GSDM, GSDM1" ENSG00000167914 "Gasdermin A" Q96QA5 17 39953263-39977768 "Predicted intracellular proteins, Transporters" Necrosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "skin 1: 58.9" "Group enriched" "Detected in some" 5 "Collecting duct cells: 3.7;Hofbauer cells: 5.0;Kupffer cells: 5.6;Macrophages: 2.6;Suprabasal keratinocytes: 2.7;Theca cells: 2.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 7.6" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "HBEC3-KT: 4.1;hTCEpi: 2.7;hTERT-HME1: 5.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA023313, HPA064826" Enhanced Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA 44000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane, Cytosol" "Nucleoplasm, Nuclear bodies" "HPA023313: AB_1850378, HPA064826: AB_2685361" "unprognostic (1.32e-2)" "unprognostic (2.01e-1)" "unprognostic (2.95e-2)" "unprognostic (1.06e-1)" "unprognostic (3.62e-1)" "unprognostic (1.97e-1)" "unprognostic (7.77e-2)" "unprognostic (1.39e-1)" "unprognostic (3.24e-1)" "unprognostic (3.52e-2)" "unprognostic (2.71e-1)" "unprognostic (2.90e-2)" "unprognostic (1.06e-2)" "unprognostic (9.86e-2)" "unprognostic (7.45e-2)" "unprognostic (3.63e-2)" "unprognostic (3.79e-2)" 3.4 0.7 0.2 0.9 0.2 0.4 3.5 0.4 0.4 0.8 0.2 0.7 0.6 0.4 6.6 3.2 0.3 0.8 0.3 0.3 0.2 0.3 0.3 0.4 0.7 0.4 0.0 0.1 0.3 1.3 0.1 1.6 0.4 0.1 1.2 0.0 0.8 0.0 0.4 58.9 0.5 0.6 0.0 0.2 0.3 0.3 0.4 0.5 0.1 0.1 3.4 1.1 1.5 0.4 0.2 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 4.1 0.0 0.1 0.2 0.5 0.4 0.2 0.0 0.1 0.8 0.0 2.7 0.5 5.4 0.0 0.0 0.0 0.1 1.3 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.5 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.1 0.4 0.0 0.0 0.1 0.0 0.3 0.2 0.0 0.0 0.9 0.1 0.1 2.2 0.0 2.6 0.0 1.3 0.8 0.1 0.1 0.6 0.9 0.7 0.1 0.1 0.2 0.5 0.5 0.2 0.2 0.4 0.4 0.3 0.2 0.4 0.0 0.4 0.0 0.4 0.4 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.0 0.0 3.7 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.2 0.2 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.0 0.0 0.1 0.7 0.0 5.0 0.0 0.1 0.7 0.0 5.6 0.6 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 2.7 0.0 0.2 2.8 0.0 0.0 GTSE1 "B99, GTSE-1" ENSG00000075218 "G2 and S-phase expressed 1" Q9NYZ3 22 46296870-46330810 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 11.2;lymphoid tissue: 19.6" "Cell type enhanced" "Detected in many" "Erythroid cells: 52.2;Extravillous trophoblasts: 31.2;Granulosa cells: 27.1;Spermatocytes: 73.6;Spermatogonia: 27.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA029457 Approved "Plasma membrane,Centrosome" Yes Yes "Cluster 45: Eosinophils - Innate immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Centrosome "Plasma membrane" "HPA029457: " "unprognostic (1.97e-1)" "unprognostic (3.07e-2)" "unprognostic (1.71e-3)" "unprognostic (2.59e-1)" "unprognostic (7.16e-2)" "unprognostic (2.40e-2)" "prognostic unfavorable (1.90e-10)" "prognostic unfavorable (4.66e-4)" "unprognostic (1.09e-1)" "unprognostic (8.37e-2)" "prognostic unfavorable (1.29e-4)" "unprognostic (3.49e-3)" "unprognostic (0.00e+0)" "unprognostic (6.52e-3)" "unprognostic (3.25e-1)" "unprognostic (1.14e-1)" "unprognostic (4.85e-2)" 0.6 0.6 0.2 5.1 0.2 11.2 0.5 0.5 0.3 0.7 0.2 2.4 4.1 0.8 0.0 3.6 0.2 0.5 0.3 0.2 0.3 0.3 0.4 0.6 9.2 0.4 0.3 0.2 0.2 0.1 0.1 2.6 0.4 0.2 2.6 0.1 0.7 0.1 0.1 2.5 2.9 1.2 0.1 2.4 1.9 7.2 0.5 19.6 0.2 0.2 8.7 1.0 1.2 0.4 59.5 27.6 53.2 42.2 1.1 3.0 25.5 50.3 23.5 71.7 58.8 29.3 21.9 55.7 13.0 19.4 32.8 30.3 48.0 12.7 45.7 33.7 52.0 37.4 38.9 22.8 0.1 67.5 43.8 0.6 1.0 30.9 15.6 7.5 31.2 39.7 29.0 67.8 43.4 33.1 60.9 33.0 37.2 24.2 30.7 59.6 59.7 36.3 11.7 10.7 27.5 37.5 48.1 30.7 21.5 23.8 26.2 25.8 25.1 40.6 75.8 33.4 53.7 38.6 19.7 56.3 25.8 32.2 60.5 0.0 0.0 0.3 0.3 0.0 0.0 0.3 0.1 0.1 0.0 0.1 0.0 0.0 0.5 0.3 0.0 0.4 0.3 0.2 0.2 0.2 0.5 0.3 0.2 0.3 0.4 0.3 0.4 0.1 0.5 0.4 1.1 0.0 0.0 0.7 7.0 2.8 1.1 2.1 0.6 0.7 2.8 3.4 1.6 0.0 0.5 0.0 0.0 19.2 6.8 7.6 0.0 0.9 5.6 2.1 4.7 3.9 1.2 52.2 0.3 0.2 31.2 5.1 16.8 4.3 0.0 27.1 6.4 1.2 19.9 0.0 0.5 9.4 2.0 7.5 4.0 3.9 0.3 4.7 0.0 0.0 0.1 0.4 0.0 0.5 0.1 0.8 0.2 0.7 19.1 1.8 0.5 0.5 0.2 0.3 6.6 2.6 5.4 73.6 27.8 11.7 2.6 1.5 5.0 1.2 13.8 1.6 GUCA2B ENSG00000044012 "Guanylate cyclase activator 2B" Q16661 1 42153410-42155820 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "intestine: 143.1" "Cell type enriched" "Detected in some" 7 "Paneth cells: 18841.5" "Cancer enhanced" "Detected in many" "liver cancer: 5.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "A549: 1.4;CACO-2: 3.8" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 1.0" "Secreted to blood" NA NA 77700 1200000 "Cluster 7: Monocytes - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" "unprognostic (2.59e-2)" "unprognostic (1.44e-2)" "unprognostic (1.34e-1)" "unprognostic (6.22e-2)" "unprognostic (1.86e-1)" 0.2 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 89.4 36.5 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 5.5 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 23.3 0.0 0.0 0.6 0.0 0.1 143.1 0.6 0.0 0.0 18.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 3.8 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.0 1098.8 0.0 0.9 1.0 0.0 0.0 0.0 22.8 0.0 0.0 47.9 0.3 0.0 0.0 0.0 22.3 0.0 0.4 3.1 0.1 0.0 0.0 107.2 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 18841.5 0.0 0.0 0.0 2568.9 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.4 1.3 0.0 55.3 0.9 HAL HIS ENSG00000084110 "Histidine ammonia-lyase" P42357 12 95972662-95996365 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Histidine metabolism" Lyase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "liver: 198.2;skin 1: 61.1" "Cell type enriched" "Detected in some" 8 "Hepatocytes: 129.6" "Cancer enriched" "Detected in some" 11 "liver cancer: 23.7" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "basophil: 56.9;neutrophil: 73.3" "Lineage enriched" "Detected in many" 5 "granulocytes: 73.3" "Cell line enhanced" "Detected in some" "BEWO: 2.2;NB-4: 2.8;THP-1: 11.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA038547, HPA038548" Enhanced Approved Cytosol NA NA 280000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 43: THP-1 - Innate immune response" "Cluster 15: Hepatocytes - Hemostasis" Cytosol "HPA038547: AB_10669541, HPA038548: AB_10673175" "unprognostic (3.39e-1)" "unprognostic (4.46e-2)" "unprognostic (1.53e-2)" "unprognostic (1.46e-1)" "unprognostic (2.32e-2)" "unprognostic (1.20e-2)" "unprognostic (5.05e-2)" "unprognostic (2.80e-2)" "unprognostic (1.52e-1)" "unprognostic (1.33e-2)" "unprognostic (9.41e-2)" "unprognostic (2.45e-1)" "unprognostic (1.31e-3)" "unprognostic (1.89e-2)" "unprognostic (3.74e-1)" "unprognostic (4.03e-2)" "unprognostic (2.87e-2)" 1.4 0.3 0.1 2.9 0.1 11.5 2.2 0.1 0.4 0.8 0.1 0.5 0.6 0.4 0.0 1.0 0.7 0.6 0.3 0.1 0.1 0.3 198.2 2.3 0.5 0.1 0.1 0.2 0.9 0.1 3.0 0.4 0.1 0.2 0.4 0.0 0.6 0.1 0.2 61.1 0.8 0.5 0.0 7.6 0.4 0.1 0.1 0.5 0.2 0.6 1.4 0.5 1.4 0.2 0.4 0.0 0.1 0.0 0.0 0.0 2.2 0.0 0.1 0.0 0.1 0.0 0.1 0.6 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.1 0.3 0.3 0.1 0.0 0.0 0.4 0.4 0.0 0.6 0.3 0.2 0.1 0.2 0.3 0.0 0.1 0.1 0.0 0.1 2.8 0.9 0.1 0.4 0.2 0.1 0.0 0.1 0.6 0.1 0.3 0.3 0.0 0.0 0.0 0.0 11.4 0.1 0.1 0.1 0.1 0.1 0.4 0.5 0.1 0.0 1.7 0.0 56.9 15.1 2.4 0.0 5.7 0.0 0.0 0.0 0.0 3.4 0.1 0.0 0.0 73.3 0.7 13.6 0.3 0.2 4.4 0.1 0.1 0.1 0.4 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.2 0.0 1.1 0.0 0.6 0.1 0.1 0.1 0.0 0.0 0.1 0.3 0.7 2.8 0.3 0.0 0.0 0.2 0.1 0.1 0.0 0.1 0.1 3.2 2.0 0.4 0.0 9.7 0.2 0.2 0.7 0.1 0.5 15.0 0.0 0.1 2.5 129.6 0.3 0.0 0.1 0.1 0.0 7.7 0.8 0.0 0.0 3.5 0.0 0.0 6.3 0.0 1.0 0.0 0.0 0.0 1.3 0.0 0.4 0.2 1.2 0.7 0.1 0.0 0.0 0.2 0.2 0.1 0.0 0.0 2.8 0.0 0.6 0.0 0.3 0.1 HAO2 "GIG16, HAOX2" ENSG00000116882 "Hydroxyacid oxidase 2" Q9NYQ3 1 119368779-119394130 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 16 "kidney: 303.7;liver: 425.6" "Group enriched" "Detected in some" 7 "Hepatocytes: 256.8;Proximal tubular cells: 450.1" "Group enriched" "Detected in some" 26 "liver cancer: 25.6;renal cancer: 11.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA050355 Uncertain Vesicles,Cytosol NA NA "Cluster 81: Kidney & Liver - Metabolism" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol Vesicles "HPA050355: " "unprognostic (1.13e-1)" "unprognostic (1.68e-2)" "unprognostic (2.07e-1)" "unprognostic (1.00e-1)" "unprognostic (6.22e-2)" "unprognostic (5.33e-3)" "unprognostic (2.80e-2)" "unprognostic (3.27e-1)" "unprognostic (3.15e-1)" "unprognostic (3.17e-1)" "unprognostic (1.41e-1)" "unprognostic (1.73e-1)" "prognostic favorable (4.92e-4)" "unprognostic (9.66e-2)" "unprognostic (1.79e-1)" "unprognostic (2.89e-2)" "unprognostic (5.14e-4)" 0.0 0.6 0.2 0.1 0.6 0.0 0.6 0.1 0.6 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.0 303.7 425.6 0.0 0.3 0.2 0.0 0.0 0.1 0.0 0.0 0.3 0.2 0.1 0.1 0.0 0.0 0.0 0.0 4.4 0.1 0.0 0.1 0.4 0.2 0.1 0.3 23.3 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.1 0.6 0.2 0.0 0.2 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 5.7 0.0 11.0 0.0 0.0 0.0 0.0 49.0 0.0 0.0 0.0 0.0 0.6 0.0 13.5 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.1 4.2 256.8 0.1 0.0 0.1 0.0 0.0 6.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 450.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 HCAR2 "GPR109A, HCA2, HM74A, NIACR1, Puma-g, PUMAG" ENSG00000182782 "Hydroxycarboxylic acid receptor 2" Q8TDS4 12 122701293-122703357 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" Apoptosis "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 40.8;skin 1: 30.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 94.4;Basal prostatic cells: 84.7;Basal respiratory cells: 52.0;Basal squamous epithelial cells: 120.1;Ionocytes: 87.5;Langerhans cells: 124.0;Suprabasal keratinocytes: 106.1" "Group enriched" "Detected in many" 8 "cervical cancer: 12.6;head and neck cancer: 16.1;lung cancer: 6.4;urothelial cancer: 9.2" "Region enriched" "Detected in some" 5 "cerebral cortex: 5.9" "Immune cell enriched" "Detected in many" 5 "neutrophil: 176.7" "Lineage enriched" "Detected in many" 7 "granulocytes: 176.7" "Cell line enriched" "Detected in some" 6 "HaCaT: 118.4" HPA028660 Approved Supported "Cell Junctions" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Cell Junctions" "HPA028660: AB_10602139" "unprognostic (5.43e-2)" "unprognostic (1.27e-1)" "unprognostic (1.77e-1)" "unprognostic (2.05e-1)" "unprognostic (6.65e-2)" "unprognostic (1.33e-1)" "unprognostic (3.33e-3)" "unprognostic (7.26e-2)" "unprognostic (2.17e-1)" "unprognostic (1.77e-2)" "unprognostic (7.10e-2)" "unprognostic (7.33e-2)" "unprognostic (4.83e-4)" "unprognostic (5.76e-2)" "unprognostic (5.07e-2)" "unprognostic (1.54e-1)" "unprognostic (4.63e-2)" 22.2 0.3 0.1 9.8 0.2 22.1 7.6 0.1 5.9 8.9 0.2 0.7 0.9 0.2 0.3 40.8 0.7 0.8 0.9 0.3 0.1 3.9 2.9 11.9 0.6 0.1 0.1 0.1 0.2 5.5 0.3 4.5 1.2 3.4 0.3 0.2 14.2 14.7 0.2 30.2 1.0 0.3 0.1 25.9 1.5 2.7 0.2 10.5 0.5 1.9 10.2 6.9 14.0 0.1 4.5 0.4 0.1 0.1 1.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 118.4 0.0 7.3 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.3 0.1 3.8 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.3 0.0 0.0 0.4 0.1 0.0 0.0 0.0 19.5 0.2 0.0 0.4 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.3 0.0 0.0 38.7 2.5 2.6 0.0 5.3 0.0 0.1 0.0 0.0 1.7 0.0 0.0 0.0 176.7 0.0 23.9 0.0 0.0 1.4 0.1 0.2 0.1 5.9 0.3 0.1 0.1 0.1 1.2 0.1 0.2 0.1 0.4 0.0 4.3 0.0 0.5 94.4 84.7 52.0 120.1 0.5 3.4 1.1 0.1 0.0 40.3 0.0 0.0 1.5 0.0 0.0 0.0 0.0 24.9 0.4 0.2 1.2 0.0 0.0 0.0 0.0 26.3 2.4 0.0 0.3 2.5 0.0 0.0 0.0 3.7 0.0 0.0 0.0 87.5 4.1 124.0 2.7 0.0 17.8 8.8 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.3 0.0 0.0 8.5 0.1 0.0 0.1 1.4 0.0 0.1 47.2 106.1 2.6 1.5 0.0 0.0 32.5 HGD "AKU, HGO" ENSG00000113924 "Homogentisate 1,2-dioxygenase" Q93099 3 120628172-120682269 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Phenylalanine catabolism, Tyrosine catabolism" "Dioxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "kidney: 200.3;liver: 752.6" "Cell type enhanced" "Detected in many" "Distal tubular cells: 103.7;Endometrial ciliated cells: 113.9;Glandular and luminal cells: 127.8;Hepatocytes: 534.7;Proximal tubular cells: 477.5" "Cancer enriched" "Detected in many" 4 "liver cancer: 119.8" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 6 "neutrophil: 1.1" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.1" "Cell line enhanced" "Detected in some" "CACO-2: 55.8;EFO-21: 82.7;Hep G2: 186.6;OE19: 328.0;RPTEC TERT1: 212.2" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebellum: 1.2" "HPA047374, HPA052359" Enhanced Approved "Golgi apparatus" NA NA 700000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Golgi apparatus" "HPA047374: AB_2680019, HPA052359: AB_2681798" "unprognostic (1.36e-1)" "unprognostic (9.89e-2)" "unprognostic (3.93e-2)" "prognostic favorable (1.78e-4)" "unprognostic (1.56e-1)" "unprognostic (2.05e-1)" "unprognostic (5.65e-3)" "unprognostic (7.20e-2)" "unprognostic (6.05e-2)" "unprognostic (2.41e-3)" "unprognostic (2.68e-2)" "unprognostic (1.16e-1)" "unprognostic (4.29e-3)" "unprognostic (8.57e-2)" "unprognostic (1.78e-1)" "unprognostic (3.71e-3)" "unprognostic (1.43e-1)" 0.4 0.3 0.4 2.5 1.9 0.5 12.5 0.6 0.8 27.4 1.5 16.7 31.6 3.1 13.0 0.4 4.2 61.7 0.3 0.5 0.4 200.3 752.6 0.8 0.4 0.4 0.4 0.2 31.2 7.0 0.2 0.2 0.4 44.5 20.3 0.7 4.2 4.2 0.1 0.9 25.6 0.5 0.4 0.6 25.5 0.1 0.5 0.7 55.1 0.2 0.1 0.2 0.1 0.6 0.0 12.3 4.6 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 55.8 10.7 0.1 82.7 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 2.3 0.2 186.6 0.0 0.4 1.0 0.0 0.2 0.1 0.0 0.1 0.1 0.4 0.0 0.3 0.5 0.0 0.0 0.2 0.3 328.0 0.0 0.1 0.3 0.1 212.2 0.0 0.2 0.2 0.2 0.9 0.0 0.0 0.2 1.0 0.6 0.1 0.9 0.2 0.1 0.0 0.3 0.5 0.2 0.8 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 2.3 0.4 1.9 0.6 0.8 0.5 0.4 0.4 0.4 0.4 0.4 0.5 0.6 0.1 0.0 2.0 0.3 5.9 0.0 0.4 0.6 0.0 0.3 7.5 1.7 0.3 81.5 4.9 27.6 2.1 0.0 0.3 18.5 103.7 7.2 0.2 113.9 17.1 1.2 43.8 24.0 3.2 17.8 0.0 0.4 19.4 127.8 1.3 0.0 16.4 534.7 0.2 0.0 0.6 16.0 2.0 16.1 0.0 0.0 0.0 21.3 0.0 1.9 2.0 4.2 0.0 0.0 0.5 12.1 35.6 0.0 0.0 12.9 54.6 477.5 4.1 0.2 0.0 0.2 1.1 0.1 0.0 0.0 0.0 0.0 3.8 0.4 9.1 0.4 HJURP "DKFZp762E1312, FAKTS, hFLEG1, URLC9" ENSG00000123485 "Holliday junction recognition protein" Q8NCD3 2 233833416-233854566 "Predicted intracellular proteins" "Cell cycle" "Chaperone, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 47.4;lymphoid tissue: 30.4" "Cell type enhanced" "Detected in many" "Early spermatids: 17.4;Erythroid cells: 38.3;Extravillous trophoblasts: 16.1;Granulosa cells: 14.8;Spermatocytes: 37.5;Spermatogonia: 16.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "T-reg: 1.2" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA008436, HPA027261" Uncertain Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitochondria" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nucleoli, Nucleoli rim" Mitochondria "HPA008436: AB_1850757, HPA027261: AB_2672184" "unprognostic (5.63e-2)" "unprognostic (9.15e-2)" "unprognostic (1.87e-1)" "unprognostic (1.44e-3)" "unprognostic (3.62e-1)" "unprognostic (1.75e-1)" "prognostic unfavorable (3.37e-5)" "prognostic unfavorable (2.46e-4)" "prognostic unfavorable (6.49e-4)" "unprognostic (9.48e-2)" "prognostic unfavorable (7.72e-5)" "unprognostic (7.60e-2)" "unprognostic (0.00e+0)" "unprognostic (7.42e-2)" "unprognostic (5.58e-2)" "unprognostic (1.89e-2)" "unprognostic (5.74e-2)" 0.6 0.6 0.0 5.5 0.1 47.4 1.1 0.1 0.2 0.8 0.1 3.9 4.1 0.9 0.2 5.6 0.3 0.5 0.3 0.1 0.1 0.4 0.8 1.4 12.6 0.1 0.3 0.2 0.2 0.1 0.1 3.0 0.1 0.4 5.2 0.1 1.0 0.1 0.2 3.6 3.8 1.9 0.0 4.1 2.4 11.1 0.3 30.4 0.3 0.0 12.0 1.4 2.0 0.2 54.5 73.6 68.4 32.7 2.6 5.4 42.8 79.5 37.9 55.2 59.9 51.3 57.6 17.1 9.0 31.4 98.0 61.7 54.9 40.9 72.6 40.0 21.6 65.5 61.4 50.9 0.3 54.1 43.2 1.8 1.5 45.1 30.9 15.7 35.5 51.3 56.6 40.8 103.0 55.3 76.4 59.7 58.9 42.2 49.1 58.4 103.0 30.3 28.6 32.3 39.4 24.7 45.8 34.2 31.7 31.0 25.7 42.1 26.0 59.6 64.6 44.3 87.2 38.6 32.7 67.9 35.7 39.3 151.6 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.3 0.1 0.4 0.0 1.2 0.4 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.3 0.1 0.0 0.3 0.2 0.2 0.0 0.5 0.0 2.9 1.3 0.5 1.9 0.0 0.0 0.7 0.5 1.2 0.0 2.1 0.0 0.0 8.2 0.5 5.6 0.0 0.2 17.4 0.3 1.3 1.1 0.0 38.3 0.0 0.0 16.1 2.0 5.1 1.3 0.0 14.8 2.2 0.3 7.1 0.0 0.0 3.5 0.0 3.0 2.9 9.0 0.6 3.5 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.2 1.4 0.0 11.4 1.0 0.5 0.1 0.1 0.0 0.0 0.1 1.9 37.5 16.3 8.9 0.9 1.5 2.3 0.3 7.6 0.9 HK1 ENSG00000156515 "Hexokinase 1" P19367 10 69269984-69401884 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycolysis, Immunity, Inflammatory response, Innate immunity" "Allosteric enzyme, Kinase, Transferase" "Cancer-related genes, Charcot-Marie-Tooth disease, Disease variant, Mental retardation, Neurodegeneration, Neuropathy, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 374.0;Horizontal cells: 304.5;Late spermatids: 1034.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007043, HPA007044, CAB010052" Supported Supported Mitochondria NA NA 560000 "Cluster 51: Monocytes - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria "CAB010052: AB_627721, HPA007043: AB_1850652, HPA007044: AB_1079049" "unprognostic (8.80e-2)" "unprognostic (1.78e-1)" "unprognostic (2.03e-1)" "unprognostic (2.00e-3)" "unprognostic (1.15e-2)" "prognostic unfavorable (3.39e-6)" "unprognostic (1.23e-1)" "unprognostic (1.97e-1)" "unprognostic (4.29e-2)" "unprognostic (1.16e-1)" "unprognostic (3.93e-3)" "unprognostic (1.12e-1)" "unprognostic (1.37e-3)" "unprognostic (7.25e-2)" "unprognostic (1.40e-2)" "unprognostic (2.00e-3)" "unprognostic (3.86e-2)" 47.0 24.4 61.0 45.0 65.7 60.3 40.6 58.0 76.6 54.7 64.2 60.1 13.1 41.3 11.2 129.9 37.0 25.7 150.8 69.1 62.7 49.2 8.5 48.1 34.1 56.7 59.8 19.9 12.3 25.0 44.9 49.3 71.1 52.9 31.9 147.6 67.1 53.1 193.5 102.6 29.2 49.8 40.0 40.3 61.6 77.2 53.5 44.9 71.0 146.7 47.6 74.3 80.9 54.1 101.6 56.6 74.2 71.1 81.0 60.4 47.1 98.3 256.5 128.5 138.0 16.3 11.0 7.3 75.8 165.9 92.9 86.2 69.9 220.0 122.0 67.5 54.5 250.0 58.3 1.1 91.7 5.1 181.2 91.5 125.8 184.5 407.6 160.8 135.4 36.8 424.5 51.3 178.7 167.7 29.7 13.1 113.8 51.7 247.0 44.8 45.0 0.6 88.7 117.4 75.7 88.7 112.6 215.4 65.2 104.3 117.7 16.5 140.4 190.5 86.4 106.5 139.6 61.1 42.8 17.4 247.3 130.4 56.1 68.7 88.8 44.6 41.5 125.2 69.0 33.5 47.9 47.6 81.0 19.9 41.7 33.9 20.9 31.2 135.4 9.1 58.1 110.4 61.0 65.7 58.0 76.6 69.1 62.7 56.7 59.8 71.1 40.0 53.5 54.1 26.1 25.6 32.4 38.2 26.5 48.3 50.5 37.8 43.9 83.9 33.1 21.7 130.6 4.3 34.2 27.6 54.2 70.6 14.6 30.3 13.7 28.6 374.0 32.6 28.0 37.9 18.7 104.8 53.8 30.6 93.3 30.3 41.3 34.5 23.4 72.6 26.7 1.1 49.4 304.5 49.8 28.7 44.7 41.7 21.9 1034.1 15.2 51.3 37.4 29.0 35.3 32.9 20.6 14.1 3.5 54.6 11.1 18.4 19.1 29.1 0.7 1.1 30.7 95.5 19.7 22.2 43.1 5.3 6.2 86.0 51.7 118.9 30.5 28.3 19.3 43.5 HLCS HCS ENSG00000159267 "Holocarboxylase synthetase" P50747 21 36748626-36990236 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ligase, Multifunctional enzyme" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 86.2;Inhibitory neurons: 99.7;Oligodendrocyte precursor cells: 79.9;Oligodendrocytes: 80.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017379 Approved Approved Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA017379: AB_1850768" "prognostic unfavorable (7.72e-4)" "unprognostic (2.41e-1)" "unprognostic (3.93e-2)" "unprognostic (2.05e-1)" "unprognostic (2.75e-1)" "unprognostic (1.44e-2)" "unprognostic (5.08e-2)" "unprognostic (2.67e-1)" "unprognostic (1.54e-1)" "unprognostic (1.03e-1)" "unprognostic (1.31e-1)" "unprognostic (7.44e-2)" "unprognostic (2.43e-1)" "unprognostic (2.55e-1)" "unprognostic (2.67e-2)" "unprognostic (1.85e-3)" "unprognostic (3.02e-1)" 5.0 5.1 4.9 4.2 5.5 3.3 7.4 9.1 5.8 5.1 9.4 4.7 4.2 4.0 7.0 6.1 5.3 4.2 3.7 6.3 5.4 6.4 10.6 4.9 3.7 5.9 4.6 3.8 7.6 10.6 8.8 4.1 6.3 8.9 4.4 6.1 8.5 6.6 13.3 2.8 4.9 4.5 4.1 3.1 5.7 5.7 5.4 3.3 10.7 6.2 4.3 5.4 2.8 5.5 23.8 10.4 13.0 9.6 14.8 13.7 13.3 13.0 12.7 7.1 7.0 10.8 11.0 10.6 6.4 21.4 13.0 8.2 5.9 11.6 5.5 21.0 9.2 16.4 9.6 6.7 14.9 8.6 11.0 10.2 17.0 10.6 23.6 15.5 9.0 12.0 19.7 31.9 17.4 14.2 4.6 5.4 21.8 16.7 11.3 7.1 7.5 11.2 10.8 24.8 8.3 9.9 16.7 8.8 14.8 10.0 16.2 9.1 10.5 9.1 2.7 8.9 7.8 25.6 19.8 7.1 14.6 11.1 10.7 1.9 0.8 0.8 3.6 2.0 2.9 1.2 1.9 2.3 0.8 1.3 2.4 2.2 1.2 4.8 5.1 1.9 1.6 1.8 4.9 5.5 9.1 5.8 6.3 5.4 5.9 4.6 6.3 4.1 5.4 5.5 3.0 9.6 12.5 46.4 4.1 3.3 9.2 5.3 6.8 12.8 9.4 7.4 4.5 8.6 8.4 12.9 22.9 8.9 5.1 3.5 7.9 7.8 5.6 8.0 8.0 3.8 6.0 7.4 86.2 8.1 5.4 5.1 9.7 8.0 5.7 7.9 4.2 18.5 4.6 18.5 99.7 5.2 4.1 5.1 2.1 4.3 4.4 4.0 0.0 45.9 3.2 5.6 8.2 79.9 80.1 9.0 2.9 7.2 4.2 7.8 8.0 6.1 9.2 14.2 0.0 9.0 6.8 5.2 11.5 8.7 4.0 5.1 5.5 11.1 5.4 6.9 HMMR "CD168, RHAMM" ENSG00000072571 "Hyaluronan mediated motility receptor" O75330 5 163460203-163491941 "CD markers, FDA approved drug targets, Predicted intracellular proteins" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 20.6;lymphoid tissue: 27.3;testis: 27.5" "Cell type enhanced" "Detected in many" "Early spermatids: 86.2;Erythroid cells: 133.3;Extravillous trophoblasts: 55.1;Late spermatids: 60.9;Spermatocytes: 100.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "T-reg: 1.5" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "CAB002433, HPA040025, HPA043926, HPA061524" Enhanced Enhanced Microtubules,Centrosome,Cytosol Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Microtubules "Centrosome, Cytosol" "CAB002433: AB_564080, HPA040025: AB_2676805, HPA043926: , HPA061524: AB_2684551" "unprognostic (3.53e-3)" "unprognostic (1.01e-1)" "unprognostic (3.38e-3)" "unprognostic (8.88e-3)" "unprognostic (2.12e-1)" "prognostic unfavorable (5.52e-4)" "prognostic unfavorable (1.93e-7)" "prognostic unfavorable (1.09e-4)" "unprognostic (5.68e-2)" "unprognostic (2.50e-1)" "prognostic unfavorable (3.71e-5)" "unprognostic (1.02e-1)" "unprognostic (0.00e+0)" "unprognostic (1.65e-2)" "unprognostic (4.98e-2)" "unprognostic (2.39e-1)" "unprognostic (1.77e-2)" 0.8 0.7 0.2 10.1 0.3 20.6 2.1 0.3 0.4 1.1 0.1 6.6 7.4 0.8 0.2 4.0 0.5 0.9 0.8 0.2 0.2 0.7 1.7 0.9 18.1 0.5 0.3 0.2 0.3 0.9 0.2 6.2 0.4 0.5 8.8 0.8 0.8 0.2 1.2 4.2 6.5 2.9 0.3 2.9 3.6 27.5 0.7 27.3 0.7 0.4 17.7 2.2 1.4 0.5 77.0 47.2 94.5 50.8 5.0 9.0 70.3 71.4 34.9 88.0 78.9 96.8 145.1 127.5 66.0 22.2 118.5 86.3 112.4 69.0 148.6 116.1 34.4 76.7 32.3 48.4 1.4 68.7 67.3 2.4 4.1 82.8 64.0 14.7 50.6 85.7 73.2 101.0 93.2 28.5 72.3 38.8 81.9 51.2 51.6 78.0 126.3 63.9 34.8 20.4 78.8 43.8 106.3 32.8 38.6 45.1 97.3 54.5 32.9 63.2 52.4 50.6 97.2 53.7 96.3 102.4 41.4 104.2 61.1 0.2 0.2 0.0 0.1 0.1 0.3 0.3 0.3 0.1 0.2 0.2 0.1 0.2 0.1 0.5 0.0 0.6 1.5 0.2 0.2 0.3 0.3 0.4 0.2 0.2 0.5 0.3 0.4 0.3 0.7 0.5 0.4 0.0 1.1 1.3 6.0 2.5 1.8 4.5 2.8 0.6 3.2 3.7 2.5 4.3 3.2 0.0 0.0 37.3 2.3 5.3 0.0 0.8 86.2 3.8 3.1 3.1 1.2 133.3 0.6 0.2 55.1 4.6 11.7 5.7 0.0 21.6 5.3 3.8 22.2 0.0 0.4 7.8 6.1 8.8 2.7 60.9 2.1 7.6 0.0 0.0 2.3 0.1 1.0 0.5 1.2 0.2 0.3 0.7 22.9 1.5 1.3 2.6 2.8 1.0 6.6 0.6 3.8 100.9 23.3 14.1 1.4 4.5 5.2 1.6 15.6 3.0 HMOX1 "bK286B10, HO-1" ENSG00000100292 "Heme oxygenase 1" P09601 22 35380361-35394214 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis Oxidoreductase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "lymphoid tissue: 612.2" "Cell type enhanced" "Detected in many" "Endothelial cells: 327.1;Extravillous trophoblasts: 285.2;Hofbauer cells: 494.9;Kupffer cells: 954.1;Macrophages: 271.5;Syncytiotrophoblasts: 502.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 98.8;intermediate monocyte: 238.8;non-classical monocyte: 329.2" "Lineage enriched" "Detected in all" 7 "monocytes: 329.2" "Cell line enhanced" "Detected in many" "BEWO: 869.1;GAMG: 631.2;U-138 MG: 506.2;U-87 MG: 489.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000635, CAB017444" Enhanced Uncertain "Golgi apparatus,Plasma membrane" NA NA 170000 "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus, Plasma membrane" "CAB017444: AB_10617276, HPA000635: AB_1079089" "unprognostic (3.12e-1)" "unprognostic (1.00e-1)" "unprognostic (9.42e-2)" "unprognostic (6.94e-2)" "unprognostic (5.57e-2)" "unprognostic (2.47e-2)" "prognostic unfavorable (1.59e-4)" "unprognostic (7.56e-2)" "unprognostic (1.71e-1)" "unprognostic (4.91e-2)" "unprognostic (1.62e-1)" "unprognostic (2.76e-1)" "unprognostic (1.95e-3)" "unprognostic (1.91e-1)" "unprognostic (4.82e-2)" "unprognostic (2.26e-1)" "unprognostic (7.54e-2)" 150.2 48.9 40.9 64.6 48.8 99.3 20.6 42.4 66.3 28.2 46.4 35.2 106.0 10.4 7.6 48.4 40.7 52.6 18.2 40.6 46.6 96.2 136.5 113.6 57.2 52.3 46.5 139.0 41.7 7.4 9.6 72.2 56.3 6.7 31.1 1.7 15.1 4.0 107.1 74.1 64.5 38.7 45.9 612.2 19.9 17.8 60.7 25.1 11.3 21.4 49.4 46.2 29.2 56.2 12.2 179.1 1.8 37.7 170.9 49.6 869.1 83.2 57.6 42.9 48.6 82.1 11.3 0.1 18.3 83.3 631.2 10.1 11.4 1.9 16.1 308.6 9.2 4.3 51.5 179.3 218.9 11.5 54.8 146.3 4.2 282.3 19.7 74.6 130.9 0.5 0.0 87.4 152.5 6.9 0.2 4.3 18.1 130.4 20.7 1.2 15.6 28.4 35.2 104.5 2.7 2.4 215.8 19.1 15.5 92.5 8.9 3.0 44.3 506.2 22.1 82.5 82.5 53.5 77.0 9.3 489.4 5.7 8.6 11.3 98.8 7.7 1.1 238.8 0.4 24.8 0.7 1.7 44.6 2.9 0.1 0.5 47.1 5.3 329.2 1.1 1.8 70.9 40.9 48.8 42.4 66.3 40.6 46.6 52.3 46.5 56.3 45.9 60.7 56.2 19.3 3.2 19.0 0.0 11.5 16.4 27.5 11.0 10.8 0.0 25.0 9.1 2.9 24.3 10.5 5.5 0.0 50.5 3.5 59.1 21.5 13.6 2.1 39.6 12.9 327.1 16.0 5.7 0.2 1.5 285.2 64.1 9.2 74.6 11.4 98.4 23.6 23.6 494.9 0.0 0.4 8.3 18.3 954.1 175.8 4.1 31.1 271.5 35.6 1.9 184.7 0.4 9.2 0.5 1.4 8.3 26.1 5.3 2.5 110.6 61.5 157.9 7.1 0.6 0.0 40.8 52.7 0.9 4.4 5.5 15.6 502.0 6.8 6.9 6.1 118.3 HPGD SDR36C1 ENSG00000164120 "15-hydroxyprostaglandin dehydrogenase" P15428 4 174490175-174523154 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism, Prostaglandin metabolism" Oxidoreductase "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "stomach 1: 235.0;urinary bladder: 376.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 457.8;Extravillous trophoblasts: 701.7;granulocytes: 864.5;Proximal enterocytes: 500.6;Urothelial cells: 922.8" "Cancer enhanced" "Detected in many" "urothelial cancer: 52.4" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "basophil: 123.7;T-reg: 45.0" "Group enriched" "Detected in many" 73 "granulocytes: 123.7;T-cells: 45.0" "Cell line enhanced" "Detected in many" "A549: 157.8;ASC diff: 110.6;HEL: 355.0;OE19: 102.1;RT4: 565.7;SuSa: 121.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004919, HPA005679" Enhanced Supported Nucleoplasm,Cytosol No NA 20000 "Cluster 46: Basophils - DNA binding" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol Nucleoplasm "HPA004919: AB_1079081, HPA005679: AB_1079080" "unprognostic (1.23e-3)" "unprognostic (1.61e-1)" "unprognostic (5.96e-2)" "unprognostic (1.25e-1)" "unprognostic (1.09e-2)" "unprognostic (2.53e-2)" "unprognostic (1.27e-1)" "unprognostic (2.23e-1)" "unprognostic (1.08e-1)" "unprognostic (4.28e-2)" "unprognostic (3.54e-3)" "unprognostic (2.34e-2)" "prognostic favorable (3.20e-4)" "unprognostic (2.44e-1)" "unprognostic (2.59e-1)" "unprognostic (1.37e-4)" "unprognostic (2.33e-2)" 9.2 16.5 1.0 11.4 0.7 2.7 159.9 0.5 1.2 32.2 8.7 60.9 152.2 45.5 36.5 81.6 13.4 24.9 1.6 1.2 2.8 60.2 210.8 91.0 5.5 1.4 2.0 1.1 2.6 85.3 2.1 99.1 1.0 10.2 57.4 1.0 7.7 4.0 2.5 39.8 117.3 63.7 0.8 10.3 235.0 1.6 2.2 12.2 1.7 3.0 26.6 376.0 83.0 0.7 0.0 157.8 0.0 0.0 110.6 5.4 0.4 0.0 0.0 0.0 0.4 45.1 0.2 0.1 0.0 0.0 0.2 14.2 16.0 0.0 0.0 0.3 2.9 355.0 10.8 0.3 0.0 2.1 0.9 5.6 2.6 0.0 0.1 0.1 0.0 22.6 0.2 0.0 0.0 0.3 1.2 0.3 1.4 102.1 7.4 16.3 0.3 1.3 36.2 565.7 0.9 0.4 0.0 1.3 3.5 121.3 0.1 0.0 0.3 0.0 0.2 0.1 0.0 28.4 0.0 0.1 0.3 0.2 0.0 123.7 0.3 16.6 9.9 0.0 15.6 0.4 5.2 4.5 0.7 0.2 1.6 4.0 1.3 1.1 0.0 0.0 45.0 3.0 1.0 0.7 0.5 1.2 1.2 2.8 1.4 2.0 1.0 0.8 2.2 0.7 3.4 16.0 33.0 0.0 4.3 17.3 80.8 6.9 45.5 3.3 14.5 6.7 0.8 35.8 23.6 22.0 0.0 48.5 38.5 457.8 21.5 7.4 1.4 5.7 5.4 18.2 8.4 17.2 0.8 94.5 701.7 25.3 196.7 36.4 864.5 1.5 13.9 245.7 21.4 0.0 9.7 60.7 0.0 14.8 19.5 0.5 19.9 29.2 76.5 5.6 2.9 0.0 10.3 0.0 4.1 42.4 254.7 0.0 50.2 76.8 500.6 131.1 4.4 0.8 0.0 2.4 3.7 0.5 1.0 53.4 22.4 56.6 42.7 65.0 58.9 922.8 HS3ST4 3OST4 ENSG00000182601 "Heparan sulfate-glucosamine 3-sulfotransferase 4" Q9Y661 16 25691959-26137685 "Enzymes, Metabolic proteins, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "brain: 38.1" "Group enriched" "Detected in some" 9 "Excitatory neurons: 431.4;Microglial cells: 536.8" "Cancer enhanced" "Detected in some" "prostate cancer: 1.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "NTERA-2: 1.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 65: Brain - Ion transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (1.09e-2)" "unprognostic (1.87e-1)" "unprognostic (2.95e-1)" "unprognostic (2.24e-1)" "unprognostic (1.43e-3)" "unprognostic (1.27e-1)" "unprognostic (3.84e-1)" "unprognostic (8.81e-3)" "unprognostic (6.71e-2)" "unprognostic (2.39e-1)" "unprognostic (1.92e-1)" "unprognostic (2.51e-2)" "unprognostic (3.67e-2)" 0.0 0.0 19.0 0.0 17.5 0.0 2.2 7.0 15.8 0.3 3.3 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 33.2 12.2 0.0 0.0 0.0 0.0 18.2 11.8 0.0 0.0 3.6 0.3 0.0 19.0 0.8 0.0 2.0 0.1 0.0 0.0 0.5 0.0 0.0 7.5 1.6 1.7 0.5 38.1 0.2 0.0 0.0 0.0 0.2 0.5 18.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.0 17.5 7.0 15.8 33.2 12.2 18.2 11.8 19.0 7.5 38.1 18.5 0.0 0.0 0.0 7.5 0.1 0.0 0.4 0.1 0.0 26.0 2.6 2.7 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 431.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 48.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 536.8 0.0 0.4 0.0 6.6 9.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 HSD3B1 "HSD3B, HSDB3, SDR11E1" ENSG00000203857 "Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1" P14060 1 119507198-119515054 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism, Steroidogenesis" "Isomerase, Multifunctional enzyme, Oxidoreductase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "placenta: 77.7" "Group enriched" "Detected in some" 8 "Extravillous trophoblasts: 140.8;Syncytiotrophoblasts: 502.0" "Cancer enriched" "Detected in single" 4 "urothelial cancer: 1.6" "Region enhanced" "Detected in some" "basal ganglia: 1.0;cerebral cortex: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "CACO-2: 64.1;SuSa: 26.5" "HPA043261, HPA043264, HPA044028" Supported Approved "Nucleoli,Endoplasmic reticulum,Cytokinetic bridge" Yes NA "Cluster 28: Placenta - Pregnancy" "Cluster 39: CACO-2 - Unknown function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Nucleoli, Endoplasmic reticulum" "Cytokinetic bridge" "HPA043261: AB_2630368, HPA043264: AB_2678398, HPA044028: AB_2678781" "unprognostic (1.53e-1)" "unprognostic (7.11e-2)" "unprognostic (1.15e-1)" "unprognostic (1.04e-1)" "prognostic favorable (4.59e-5)" 0.1 1.2 0.2 0.0 1.0 0.0 1.5 0.0 1.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 77.7 0.0 0.1 0.5 0.0 0.1 0.0 0.1 4.5 8.7 0.5 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.2 0.0 0.0 0.0 64.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 7.0 0.7 0.8 26.5 0.0 0.0 0.2 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.0 0.0 1.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 23.6 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 140.8 0.8 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 37.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 502.0 0.0 0.1 1.0 0.0 HSPB1 "CMT2F, Hs.76067, Hsp25, HSP27, HSP28" ENSG00000106211 "Heat shock protein family B (small) member 1" P04792 7 76302673-76304295 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Stress response" Chaperone "Cancer-related genes, Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 5909.6" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 16589.4;Exocrine glandular cells: 6539.7;Squamous epithelial cells: 6300.1;Urothelial cells: 13091.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTCEpi: 2482.8;MCF7: 3979.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000497, CAB004439, CAB047330, CAB047331, CAB047332" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA 19000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cytosol" "CAB004439: AB_627755, CAB047330: , CAB047331: , CAB047332: , HPA000497: AB_1851172" "unprognostic (2.55e-1)" "unprognostic (7.25e-3)" "prognostic unfavorable (9.94e-5)" "unprognostic (7.07e-3)" "unprognostic (3.47e-3)" "unprognostic (6.61e-3)" "unprognostic (4.08e-3)" "unprognostic (4.50e-2)" "unprognostic (1.27e-1)" "unprognostic (9.78e-2)" "unprognostic (8.70e-2)" "unprognostic (2.21e-1)" "unprognostic (5.72e-2)" "unprognostic (5.18e-2)" "unprognostic (2.67e-1)" "unprognostic (2.56e-1)" "unprognostic (3.63e-1)" 964.4 856.4 810.6 329.6 835.1 52.3 560.5 821.6 1798.8 2123.4 864.3 2043.6 208.7 2824.2 131.7 5909.6 993.8 217.2 2981.9 776.6 944.5 986.4 554.9 790.9 99.0 894.1 838.7 731.6 751.7 221.1 303.3 324.3 870.8 979.0 73.8 10.2 1075.3 522.5 3669.8 2258.3 523.8 1066.9 808.2 224.5 770.3 99.8 840.0 218.7 627.1 628.1 279.3 1579.4 3398.4 869.5 1251.1 902.4 79.5 576.8 487.3 447.5 5.1 514.9 249.8 260.9 325.8 84.8 660.7 8.5 389.1 599.1 514.1 1094.2 359.0 279.6 76.5 690.9 106.4 41.5 611.4 345.5 267.9 69.9 466.5 542.8 2482.8 370.0 50.5 436.6 831.3 169.5 459.4 1079.7 276.5 3979.7 117.1 508.9 407.4 212.7 800.6 417.3 195.8 974.5 342.8 423.2 7.6 529.1 363.8 1323.3 456.0 224.5 1674.9 551.6 504.2 778.8 1200.3 221.7 1310.1 85.7 145.9 10.7 575.9 247.2 579.5 19.7 13.6 10.9 58.8 78.2 28.1 115.0 92.4 62.1 31.5 105.5 102.1 88.2 5.8 79.7 112.8 56.5 64.5 46.7 810.6 835.1 821.6 1798.8 776.6 944.5 894.1 838.7 870.8 808.2 840.0 869.5 708.2 272.4 186.4 78.4 145.4 1849.8 16589.4 3603.0 1728.4 243.4 312.5 174.4 822.3 264.5 1899.4 1144.0 323.2 161.7 62.0 824.2 1500.7 2021.4 11.9 1181.8 1060.9 1038.7 422.0 136.1 4.3 6539.7 399.4 998.5 219.2 1227.1 216.7 136.3 725.7 234.7 1199.8 70.7 2.2 433.0 1245.1 147.7 2828.9 30.8 299.5 1024.8 2056.2 35.6 188.0 171.4 50.4 8.0 2.7 2719.4 1417.1 534.5 296.9 3854.8 95.3 2324.4 1253.9 29.2 611.4 551.2 2129.1 20.3 105.5 6300.1 2241.7 2432.7 758.2 68.2 390.5 13091.2 HSPB8 "CMT2L, E2IG1, H11, HSP22" ENSG00000152137 "Heat shock protein family B (small) member 8" Q9UJY1 12 119171555-119224855 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Stress response" Chaperone "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 897.3" "Group enriched" "Detected in many" 6 "Cardiomyocytes: 599.1;Syncytiotrophoblasts: 1340.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 89.6;HeLa: 66.0;MCF7: 130.5;U-87 MG: 67.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015876 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol Nucleoplasm "HPA015876: AB_1850458" "unprognostic (1.52e-2)" "unprognostic (6.97e-2)" "unprognostic (1.96e-2)" "unprognostic (1.42e-1)" "unprognostic (1.88e-1)" "unprognostic (1.99e-3)" "prognostic unfavorable (2.98e-4)" "unprognostic (2.47e-1)" "unprognostic (4.03e-2)" "unprognostic (7.91e-2)" "unprognostic (6.48e-3)" "unprognostic (1.11e-1)" "unprognostic (1.30e-1)" "unprognostic (2.05e-3)" "unprognostic (2.05e-1)" "unprognostic (6.36e-2)" "unprognostic (2.17e-2)" 57.0 13.9 172.2 34.4 172.6 0.0 33.4 179.5 141.8 58.1 147.0 381.0 8.9 114.4 10.1 163.2 58.7 43.1 469.3 147.8 231.0 63.3 4.8 95.7 11.4 188.3 206.1 23.4 30.8 183.1 17.5 92.1 193.0 143.5 35.8 28.2 50.8 289.0 897.3 70.5 50.5 114.1 211.5 56.2 110.4 12.0 193.6 40.3 29.2 448.5 98.7 239.2 100.1 235.5 21.1 16.1 0.3 0.0 14.4 11.5 60.2 32.5 28.7 5.9 0.3 40.0 0.6 0.1 89.6 42.4 48.0 2.4 0.3 0.0 0.6 0.1 1.2 0.0 66.0 3.2 11.2 0.0 0.1 14.1 4.1 22.3 1.3 21.6 12.3 0.0 0.2 0.0 13.0 130.5 0.0 0.2 5.7 0.0 23.0 0.0 22.9 2.9 38.3 6.2 0.4 1.0 13.5 1.6 6.8 50.5 29.0 0.2 20.4 15.8 39.8 21.7 1.7 0.0 0.2 0.2 67.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 172.2 172.6 179.5 141.8 147.8 231.0 188.3 206.1 193.0 211.5 193.6 235.5 2.7 44.8 48.2 42.1 0.7 102.3 108.5 4.5 126.3 0.7 95.2 17.5 599.1 7.2 5.4 5.5 8.4 149.1 1.0 0.0 0.0 59.7 12.2 98.1 20.2 27.4 0.0 0.0 6.2 11.4 17.5 82.2 5.6 142.7 1.3 0.0 25.4 0.0 19.4 1.7 6.6 0.0 2.0 1.0 9.4 11.0 1.5 1.6 12.4 2.8 1.0 51.7 0.0 0.0 0.9 12.9 0.0 0.4 0.3 24.6 0.0 52.0 3.1 2.1 6.6 39.8 76.9 0.9 0.2 38.0 28.7 1340.0 3.5 0.1 0.2 72.7 IDH1 ENSG00000138413 "Isocitrate dehydrogenase (NADP(+)) 1" O75874 2 208236229-208266074 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glyoxylate bypass, Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 536.3" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 320.2;Granulosa cells: 257.5;Hepatocytes: 328.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 768.1;RT4: 524.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033218, HPA035248, HPA057936, CAB062556" Enhanced Approved "Nuclear bodies,Cytosol" NA NA 16000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 40: Granulosa cells - Unknown function" "Nuclear bodies, Cytosol" "CAB033218: AB_2123166, CAB062556: AB_2665593, HPA035248: AB_10600714, HPA057936: AB_2683559" "unprognostic (2.79e-1)" "unprognostic (1.00e-1)" "unprognostic (1.02e-1)" "unprognostic (2.47e-3)" "unprognostic (1.93e-1)" "unprognostic (2.39e-2)" "prognostic unfavorable (6.93e-5)" "unprognostic (3.32e-1)" "unprognostic (2.20e-3)" "unprognostic (8.03e-2)" "unprognostic (5.54e-2)" "unprognostic (4.18e-3)" "prognostic unfavorable (2.45e-5)" "unprognostic (2.09e-1)" "unprognostic (1.77e-1)" "unprognostic (1.13e-1)" "unprognostic (2.69e-2)" 150.8 230.8 24.0 37.5 23.9 10.7 63.0 24.6 30.9 67.9 40.8 124.9 179.4 22.9 164.9 92.2 36.6 69.5 25.3 23.5 26.1 122.0 536.3 49.8 33.3 26.4 25.7 84.4 39.9 42.0 16.7 82.5 25.9 214.6 131.2 35.0 59.3 79.1 25.7 23.6 117.4 43.8 25.5 40.1 113.6 57.0 30.0 21.8 45.5 28.1 29.8 153.1 39.9 30.6 66.5 109.6 152.5 63.3 275.1 191.4 86.7 26.3 122.3 44.2 107.3 176.1 159.1 13.1 168.8 84.4 181.6 101.4 112.4 130.7 43.0 8.8 41.7 56.7 87.3 768.1 367.3 37.0 54.7 169.5 278.0 102.7 74.2 69.8 126.1 37.2 58.1 44.5 68.9 42.8 26.3 66.2 284.5 479.7 43.9 25.2 54.8 37.8 206.3 524.0 25.9 45.2 100.5 99.7 351.7 161.2 37.9 111.0 81.1 45.2 44.1 65.3 29.6 20.8 34.5 16.9 148.2 226.7 37.0 12.4 70.1 11.0 9.1 32.3 10.6 10.6 8.2 10.9 50.9 10.1 6.7 7.8 13.8 17.2 15.5 18.8 15.1 29.9 24.0 23.9 24.6 30.9 23.5 26.1 26.4 25.7 25.9 25.5 30.0 30.6 13.9 12.8 49.5 39.2 20.2 12.4 18.8 60.5 52.3 19.5 61.8 31.5 21.8 45.8 69.1 29.5 25.0 320.2 23.7 106.8 21.5 31.1 13.8 31.0 23.4 22.0 58.4 30.3 16.6 86.5 178.8 29.6 76.0 108.8 14.0 257.5 39.7 328.2 175.3 11.8 16.2 98.4 57.0 130.2 23.8 11.2 24.5 71.7 26.6 19.7 47.8 25.4 18.6 66.4 20.0 44.8 55.5 29.3 13.7 53.2 181.2 108.5 21.9 56.6 13.1 7.8 23.6 8.0 26.2 82.4 14.9 95.6 19.8 127.1 129.3 46.7 IFFO2 ENSG00000169991 "Intermediate filament family orphan 2" Q5TF58 1 18904280-18956676 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 43.0;skin 1: 169.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 121.0;Basal prostatic cells: 83.0;Suprabasal keratinocytes: 100.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 18 "basophil: 12.6" "Lineage enriched" "Detected in single" 18 "granulocytes: 12.6" "Cell line enhanced" "Detected in many" "HDLM-2: 139.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015987, HPA064603" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 44: HDLM-2 - Immune response" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Plasma membrane" "HPA015987: AB_2121678, HPA064603: AB_2685296" "unprognostic (1.43e-1)" "unprognostic (1.06e-2)" "unprognostic (2.81e-2)" "unprognostic (1.18e-1)" "unprognostic (1.39e-1)" "unprognostic (2.08e-2)" "unprognostic (2.03e-2)" "unprognostic (1.78e-1)" "unprognostic (4.34e-2)" "unprognostic (2.27e-3)" "unprognostic (3.24e-3)" "unprognostic (7.42e-2)" "unprognostic (3.24e-2)" "unprognostic (5.24e-3)" "unprognostic (2.72e-1)" "unprognostic (4.71e-1)" "unprognostic (1.36e-1)" 5.3 9.2 7.4 8.2 6.6 10.4 12.6 19.6 10.6 12.3 0.6 9.0 2.0 7.4 2.4 43.0 5.2 7.0 4.2 6.4 7.9 6.8 5.8 7.5 8.6 11.2 9.3 3.3 19.1 10.7 6.5 7.2 9.7 9.4 2.8 4.3 14.4 9.1 7.9 169.9 3.9 7.1 6.8 6.3 4.4 1.8 9.6 6.2 6.4 4.2 14.0 8.5 21.6 8.8 23.3 37.2 9.9 27.4 6.2 4.9 16.0 17.2 11.4 9.2 6.4 51.5 26.6 0.3 21.6 13.1 10.6 57.6 7.6 36.6 7.4 139.3 6.7 0.4 7.1 20.4 4.5 4.0 21.3 3.2 36.3 12.4 15.7 15.2 19.9 1.2 1.4 4.6 6.1 4.9 3.9 3.7 4.2 23.9 8.8 13.1 6.1 9.8 5.4 14.9 31.6 1.7 13.1 18.2 12.6 10.1 4.9 2.1 54.6 12.4 17.2 7.3 50.5 9.7 11.3 0.8 8.3 5.7 14.8 12.6 0.2 0.0 0.4 0.3 0.5 0.5 0.3 0.4 0.1 0.2 0.3 0.6 0.0 0.2 0.0 0.4 0.3 0.1 7.4 6.6 19.6 10.6 6.4 7.9 11.2 9.3 9.7 6.8 9.6 8.8 4.1 3.2 5.4 5.5 6.0 121.0 83.0 24.1 40.5 6.8 11.5 13.5 6.8 12.8 9.7 1.8 0.0 5.1 20.9 4.9 1.9 17.3 1.3 23.3 5.9 7.7 2.4 3.2 8.5 17.6 5.4 4.7 3.1 10.2 3.8 0.8 4.6 3.4 2.4 25.2 9.6 1.3 2.0 1.6 17.1 4.5 1.2 6.8 14.2 1.0 3.5 4.4 8.2 11.6 8.8 14.6 3.3 3.0 15.5 15.0 0.8 9.3 23.1 1.8 0.0 3.5 7.5 0.8 0.4 32.4 100.3 4.0 13.9 0.4 1.3 44.2 IGHA1 ENSG00000211895 "Immunoglobulin heavy constant alpha 1" P01876 14 105703995-105708665 "Disease related genes, Immunoglobulin genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 7411.2;lymphoid tissue: 6397.6;salivary gland: 8904.9;stomach 1: 6664.9" "Group enriched" "Detected in many" 10 "B-cells: 17763.5;Plasma cells: 34095.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 203 "memory B-cell: 2571.8;naive B-cell: 1114.6" "Lineage enriched" "Detected in many" 284 "B-cells: 2571.8" "Cell line enhanced" "Detected in many" "HDLM-2: 17.4;RPMI-8226: 34.7;SH-SY5Y: 22.3;U-266/70: 78.2;U-266/84: 24.0" "HPA001217, HPA006013" Approved "Immunoglobulin genes" NA NA 130000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA001217: AB_1079120, HPA006013: AB_1079119" "prognostic favorable (8.87e-5)" "unprognostic (5.36e-3)" "unprognostic (2.10e-2)" "unprognostic (1.59e-2)" "unprognostic (3.75e-2)" "prognostic favorable (3.81e-5)" "unprognostic (1.17e-1)" "unprognostic (3.86e-1)" "unprognostic (2.62e-1)" "unprognostic (3.26e-2)" "unprognostic (1.66e-1)" "unprognostic (1.34e-1)" "prognostic unfavorable (1.83e-7)" "unprognostic (8.10e-2)" "unprognostic (5.08e-2)" "unprognostic (1.16e-1)" "unprognostic (2.99e-2)" 200.6 41.7 1.4 1121.1 1.0 918.5 953.5 0.7 6.5 214.3 4.2 5973.6 7411.2 79.9 3.5 641.9 203.5 662.9 73.8 0.6 1.3 278.5 327.7 1305.3 1420.6 3.5 1.1 40.6 115.1 3.5 38.3 6.7 1.1 202.5 1338.5 0.0 8904.9 69.0 10.8 56.7 3788.8 69.5 1.4 6397.6 6664.9 23.2 1.0 131.0 447.3 0.4 1949.0 1616.2 302.9 1.9 0.0 0.0 0.0 0.0 0.0 0.0 16.4 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.8 0.0 0.0 3.6 0.0 0.0 0.0 17.4 0.0 3.7 0.0 0.0 0.0 5.4 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.1 0.0 0.0 4.1 14.4 5.5 0.0 0.0 3.8 4.3 34.7 0.0 0.0 9.7 22.3 2.6 0.0 0.0 0.0 0.0 1.6 5.1 0.0 3.9 4.2 3.2 78.2 24.0 2.2 0.0 2.4 0.0 3.8 3.0 0.6 1.3 0.3 1.0 2571.8 0.7 1.1 1.5 1114.6 0.4 1.0 9.0 0.9 0.9 1.7 1.0 508.3 1.4 1.0 0.7 6.5 0.6 1.3 3.5 1.1 1.1 1.4 1.0 1.9 11.8 131.4 783.5 0.0 17763.5 0.0 26.0 0.0 1.2 0.0 22.4 4.6 4.7 22.8 46.4 0.0 0.0 0.7 55.5 20.8 0.0 0.0 0.0 0.1 0.1 26.5 28.4 167.0 0.0 0.0 0.5 56.5 99.4 0.1 584.8 0.0 353.8 225.1 1.6 0.0 0.0 13.6 0.0 57.8 0.0 0.0 0.0 34.6 0.0 0.0 6.7 0.0 11.3 0.0 0.0 0.0 12.8 0.0 34095.8 33.2 0.0 1.4 16.0 0.0 0.0 2.0 13.6 0.0 0.0 0.8 0.0 6.0 2514.2 0.0 27.9 1.2 IGHA2 ENSG00000211890 "Immunoglobulin heavy constant alpha 2 (A2m marker)" P01877 14 105583731-105588395 "Immunoglobulin genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 5017.7;salivary gland: 3728.4" "Group enriched" "Detected in many" 22 "B-cells: 3713.4;Plasma cells: 10918.5" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 876 "memory B-cell: 279.6;naive B-cell: 123.8" "Lineage enriched" "Detected in single" 1214 "B-cells: 279.6" "Group enriched" "Detected in some" 42 "U-266/70: 181.9;U-266/84: 63.9" "Not detected" "Not detected" "HPA001217, HPA006013" Approved "Immunoglobulin genes" NA NA 67000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA001217: AB_1079120, HPA006013: AB_1079119" "prognostic favorable (1.98e-9)" "unprognostic (3.20e-2)" "unprognostic (2.23e-2)" "unprognostic (1.53e-2)" "unprognostic (1.93e-2)" "prognostic favorable (8.40e-5)" "unprognostic (4.56e-2)" "unprognostic (2.59e-1)" "unprognostic (3.17e-1)" "unprognostic (3.69e-2)" "unprognostic (1.20e-1)" "unprognostic (1.18e-1)" "prognostic unfavorable (7.50e-6)" "unprognostic (2.12e-1)" "unprognostic (3.28e-2)" "unprognostic (9.70e-2)" "unprognostic (4.47e-1)" 24.3 3.7 0.0 14.2 0.0 12.4 329.7 0.0 0.0 47.6 0.0 5017.7 15.3 8.9 0.0 219.7 35.0 0.9 4.8 0.0 0.0 49.7 35.1 134.2 6.8 0.0 0.0 5.3 30.3 0.0 4.9 0.3 0.0 37.7 8.8 0.0 3728.4 0.1 2.1 17.8 2261.3 1.0 0.0 700.9 670.1 1.1 0.0 22.4 59.8 0.0 13.0 93.4 67.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 2.8 0.0 0.0 2.8 2.8 0.0 0.0 0.0 0.0 0.0 0.3 1.0 0.0 0.1 0.0 0.9 181.9 63.9 0.5 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.2 279.6 0.0 0.1 0.1 123.8 0.0 0.1 0.2 0.0 0.1 0.1 0.1 12.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 3.2 12.4 0.0 3713.4 0.0 2.4 0.0 2.8 0.0 1.4 0.3 1.2 5.7 0.6 0.0 0.0 0.1 3.2 3.7 0.0 0.0 0.0 0.0 0.0 15.6 8.5 56.2 0.0 0.0 0.0 8.0 10.7 0.0 15.2 0.0 78.9 6.0 0.3 0.0 0.0 2.9 0.0 10.8 0.0 0.0 0.0 1.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.3 0.0 10918.5 0.3 0.0 0.1 0.0 0.0 0.0 0.1 23.6 0.0 0.0 12.3 0.0 0.4 325.4 0.0 4.8 0.2 IGHE ENSG00000211891 "Immunoglobulin heavy constant epsilon" P01854 14 105597691-105601728 "Immunoglobulin genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 1.9;lymphoid tissue: 4.6;thyroid gland: 2.6" "Cell type enriched" "Detected in some" 50 "Plasma cells: 462.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 10 "U-266/70: 3818.2" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 77000000 "Cluster 64: Macrophages - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "unprognostic (3.18e-2)" "unprognostic (1.28e-2)" "unprognostic (1.54e-3)" "unprognostic (4.99e-1)" "unprognostic (4.87e-3)" "unprognostic (1.51e-1)" "unprognostic (1.13e-1)" "unprognostic (5.36e-2)" "unprognostic (2.40e-2)" "unprognostic (8.04e-2)" "unprognostic (3.88e-2)" "unprognostic (3.01e-3)" "unprognostic (1.07e-2)" "unprognostic (3.98e-1)" "unprognostic (2.17e-1)" "unprognostic (1.63e-1)" 0.8 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.1 1.9 0.0 0.0 4.6 1.4 0.0 0.0 0.2 2.6 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.9 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.6 0.0 0.0 0.6 0.0 0.6 3818.2 371.6 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 462.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.0 IGHJ3 ENSG00000242887 "Immunoglobulin heavy joining 3" 14 105864587-105864635 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "esophagus: 36.4;intestine: 57.9;pancreas: 61.6" "Cell type enriched" "Detected in single" 48 "Plasma cells: 24.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 7 "basophil: 9.0;naive B-cell: 29.1" "Group enriched" "Detected in many" 7 "B-cells: 29.1;granulocytes: 9.0" "Cell line enhanced" "Detected in some" "Daudi: 1.5;RPMI-8226: 6.1;TIME: 8.0;U-251 MG: 2.6" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (8.67e-4)" "unprognostic (8.67e-3)" "unprognostic (1.12e-1)" "unprognostic (2.42e-2)" "prognostic favorable (3.86e-5)" "unprognostic (3.12e-1)" "unprognostic (2.21e-1)" "unprognostic (2.82e-1)" "unprognostic (4.22e-2)" "unprognostic (2.03e-1)" "unprognostic (5.70e-2)" "prognostic unfavorable (3.24e-4)" "unprognostic (8.47e-2)" "unprognostic (2.54e-1)" "unprognostic (9.62e-2)" "unprognostic (1.30e-1)" 16.2 3.0 0.6 0.0 0.9 0.0 0.0 0.2 2.5 1.9 0.5 0.0 0.0 0.0 0.0 36.4 0.7 9.1 0.0 0.6 0.9 0.9 10.2 17.3 0.0 1.5 0.4 11.3 61.6 0.0 0.0 0.0 1.7 7.5 57.9 0.1 0.0 4.3 0.0 2.4 0.0 0.0 1.4 0.0 0.0 0.3 0.7 0.0 2.4 0.0 0.0 5.2 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 9.0 0.0 0.4 0.2 0.0 0.9 0.0 0.7 1.1 2.6 29.1 1.5 1.2 0.0 0.4 0.7 0.0 1.2 0.0 0.6 0.9 0.2 2.5 0.6 0.9 1.5 0.4 1.7 1.4 0.7 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 IGHJ4 ENSG00000240041 "Immunoglobulin heavy joining 4" 14 105864215-105864260 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 416.7;lymphoid tissue: 1568.0;urinary bladder: 551.2" "Cell type enriched" "Detected in single" 148 "Plasma cells: 103.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 187 "memory B-cell: 6029.7;naive B-cell: 2618.0" "Lineage enriched" "Detected in all" 261 "B-cells: 6029.7" "Cell line enriched" "Detected in some" 87 "U-698: 3990.3" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" 0.0 0.0 7.2 0.0 2.9 0.0 240.0 0.9 10.8 0.0 3.6 377.5 0.0 0.0 0.0 200.2 7.4 4.1 12.3 0.9 2.5 0.0 39.1 0.0 0.0 8.9 30.7 0.0 0.0 13.6 0.0 2.5 22.3 7.0 416.7 0.0 0.0 0.0 0.0 20.7 0.0 0.0 2.0 45.4 7.3 3.7 3.1 32.3 3.9 0.0 1568.0 551.2 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 19.9 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.8 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 10.1 0.0 0.0 14.0 17.5 0.0 0.0 0.0 0.0 6.8 3.6 0.0 0.0 0.0 0.0 0.0 8.9 0.0 45.8 0.0 0.0 6.2 0.0 3990.3 0.0 12.2 0.0 13.9 3.6 5.4 5.0 1.3 3.0 6029.7 13.2 4.0 23.1 2618.0 1.5 6.0 20.1 3.3 6.0 0.0 6.6 1048.2 7.2 2.9 0.9 10.8 0.9 2.5 8.9 30.7 22.3 2.0 3.1 1.7 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 103.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV1-3 VI-3B ENSG00000211935 "Immunoglobulin heavy variable 1-3" A0A0C4DH29 14 106005095-106005574 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 223.2;lymphoid tissue: 629.4" "Cell type enriched" "Detected in some" 335 "Plasma cells: 13473.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "memory B-cell: 52.8;naive B-cell: 27.8" "Lineage enriched" "Detected in many" 9 "B-cells: 52.8" "Cell line enriched" "Detected in some" 11 "Karpas-707: 148.5" "Immunoglobulin genes" NA NA 2600000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.39e-2)" "unprognostic (3.81e-3)" "unprognostic (2.96e-2)" "unprognostic (4.93e-2)" "unprognostic (7.41e-3)" "unprognostic (2.42e-1)" "unprognostic (7.85e-2)" "unprognostic (5.60e-2)" "unprognostic (3.07e-1)" "unprognostic (2.58e-1)" "prognostic unfavorable (5.67e-7)" "unprognostic (7.02e-2)" "unprognostic (4.31e-1)" "unprognostic (1.75e-1)" "unprognostic (3.26e-1)" 10.6 59.3 0.0 207.8 0.0 36.4 46.7 0.0 0.5 41.6 0.3 193.3 218.5 4.8 15.3 45.5 6.5 85.4 3.2 0.0 0.1 8.2 8.9 40.9 171.8 0.2 0.0 8.4 7.0 0.3 0.6 0.1 0.1 6.0 223.2 0.0 120.6 23.5 0.6 0.9 140.9 11.2 0.0 246.6 189.1 0.4 0.1 57.8 24.2 0.0 629.4 92.1 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.7 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 14.1 1.0 148.5 0.0 0.0 0.8 1.1 0.1 0.0 0.0 0.0 0.7 0.7 0.0 0.0 10.0 8.9 0.1 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.7 0.0 2.8 1.4 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 52.8 0.6 0.2 0.0 27.8 1.6 0.5 0.0 0.0 0.0 5.8 1.7 6.1 0.0 0.0 0.0 0.5 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 40.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 27.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13473.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 4.5 0.0 0.0 0.0 IGHV2-5 ENSG00000211937 "Immunoglobulin heavy variable 2-5" P01817 14 106037902-106038365 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 465.8;lymphoid tissue: 1426.6;stomach 1: 707.9" "Cell type enriched" "Detected in some" 333 "Plasma cells: 9414.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 22 "memory B-cell: 66.7;naive B-cell: 67.3" "Lineage enriched" "Detected in many" 22 "B-cells: 67.3" "Cell line enriched" "Detected in some" 5 "Karpas-707: 8.8" "Immunoglobulin genes" NA NA 700000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.38e-2)" "unprognostic (4.10e-3)" "unprognostic (2.51e-2)" "unprognostic (6.62e-3)" "prognostic favorable (1.41e-4)" "unprognostic (1.66e-1)" "unprognostic (1.35e-1)" "unprognostic (3.63e-1)" "unprognostic (1.47e-1)" "unprognostic (8.45e-2)" "unprognostic (3.38e-1)" "prognostic unfavorable (2.09e-6)" "unprognostic (2.74e-2)" "unprognostic (1.69e-1)" "unprognostic (4.15e-1)" "unprognostic (1.56e-1)" 16.9 5.0 0.0 183.0 0.2 112.8 106.0 0.0 0.5 45.0 0.2 465.8 266.6 7.5 2.5 27.9 10.7 65.0 5.8 0.0 0.1 20.9 16.4 83.9 188.0 0.5 0.2 13.8 9.3 1.0 1.1 0.3 0.7 9.4 296.3 0.0 201.4 8.8 0.4 2.9 177.0 17.4 0.3 351.0 707.9 2.3 0.0 121.5 27.6 0.0 1426.6 249.3 12.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 8.8 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.2 1.6 0.4 0.0 0.1 1.2 1.8 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.3 0.4 0.6 0.0 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 66.7 0.0 0.0 0.1 67.3 0.1 0.1 3.0 0.0 0.0 0.0 0.0 10.5 0.0 0.2 0.0 0.5 0.0 0.1 0.5 0.2 0.7 0.3 0.0 0.4 0.0 0.0 0.0 0.0 28.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.1 27.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 3.4 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9414.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 3.2 0.0 0.0 0.0 IGHV3-15 ENSG00000211943 "Immunoglobulin heavy variable 3-15" A0A0B4J1V0 14 106153624-106154163 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 183.3;lymphoid tissue: 380.2;salivary gland: 177.7;stomach 1: 112.8;urinary bladder: 172.6" "Cell type enriched" "Detected in some" 112 "Plasma cells: 6281.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 9 "MAIT T-cell: 21.6;memory B-cell: 24.4" "Group enriched" "Detected in many" 9 "B-cells: 24.4;T-cells: 21.6" "Cell line enhanced" "Detected in some" "BEWO: 2.2;Daudi: 1.9;HL-60: 2.1;K-562: 2.0;NB-4: 2.4;RH-30: 1.9;RPMI-8226: 4.1;SH-SY5Y: 3.7" "Immunoglobulin genes" NA NA 20000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (8.85e-5)" "unprognostic (2.07e-1)" "unprognostic (1.94e-2)" "unprognostic (1.41e-2)" "unprognostic (1.62e-2)" "prognostic favorable (3.34e-5)" "unprognostic (5.20e-2)" "unprognostic (2.44e-1)" "unprognostic (9.67e-2)" "unprognostic (3.24e-2)" "unprognostic (2.53e-1)" "unprognostic (2.19e-1)" "prognostic unfavorable (1.49e-7)" "unprognostic (6.85e-2)" "unprognostic (6.92e-2)" "unprognostic (7.12e-2)" "unprognostic (3.63e-1)" 12.2 36.8 0.0 24.7 0.5 1.8 23.2 0.0 1.2 13.0 0.1 183.3 4.5 5.0 0.9 11.7 16.3 29.6 1.4 0.0 0.2 9.1 10.6 40.0 0.0 1.0 0.0 5.8 19.1 0.4 1.3 0.4 0.3 9.5 14.6 0.0 177.7 23.0 0.8 4.2 107.2 0.3 0.0 380.2 112.8 0.5 0.0 0.0 14.9 0.0 10.4 172.6 9.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.8 2.4 0.7 0.0 0.0 0.0 1.9 4.1 0.0 0.0 0.0 3.7 0.4 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.6 0.1 0.4 1.6 0.0 0.2 0.0 0.3 0.0 0.2 0.2 0.1 0.1 0.0 21.6 24.4 0.1 0.2 0.2 0.0 0.2 0.1 2.5 0.0 0.0 0.2 0.1 1.8 0.0 0.5 0.0 1.2 0.0 0.2 1.0 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 56.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.0 1.1 8.2 0.0 0.0 0.1 1.1 0.6 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6281.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.3 0.0 IGHV3-21 ENSG00000211947 "Immunoglobulin heavy variable 3-21" A0A0B4J1V1 14 106235064-106235594 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 209.7;lymphoid tissue: 398.1;salivary gland: 213.2" "Cell type enriched" "Detected in some" 86 "Plasma cells: 3885.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 2.1;NB-4: 2.1;NTERA-2: 1.2;RH-30: 2.3;TIME: 1.9" "Immunoglobulin genes" NA NA 37000000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.30e-4)" "unprognostic (1.21e-2)" "unprognostic (7.19e-3)" "unprognostic (1.51e-2)" "unprognostic (9.16e-3)" "prognostic favorable (9.34e-4)" "unprognostic (3.15e-2)" "unprognostic (1.76e-1)" "unprognostic (4.42e-2)" "unprognostic (3.03e-2)" "unprognostic (2.48e-1)" "unprognostic (4.05e-1)" "prognostic unfavorable (9.31e-8)" "unprognostic (1.73e-1)" "unprognostic (3.19e-1)" "unprognostic (1.35e-1)" "unprognostic (1.77e-1)" 18.1 2.7 0.3 0.0 0.3 0.0 24.8 0.2 1.1 16.8 0.3 209.7 0.0 7.1 0.9 17.4 30.9 0.0 2.0 0.2 0.3 15.4 10.7 55.3 0.0 0.4 0.3 2.9 16.2 2.3 1.3 0.6 0.4 7.2 0.0 0.0 213.2 0.3 0.4 4.3 111.3 0.8 0.4 398.1 83.0 0.4 0.3 0.0 25.6 0.0 0.0 27.7 10.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 2.1 1.2 0.0 0.0 0.7 2.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.1 0.1 0.0 0.0 0.0 0.6 0.0 0.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.3 0.3 0.2 1.1 0.2 0.3 0.4 0.3 0.4 0.4 0.3 1.0 0.0 0.0 0.0 0.0 44.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 1.0 21.4 0.0 0.0 0.1 0.7 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3885.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.2 0.0 IGHV3-30 ENSG00000270550 "Immunoglobulin heavy variable 3-30" "P01768, P0DP03" 14 106335082-106335613 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 534.0;lymphoid tissue: 1294.8;salivary gland: 459.9;stomach 1: 572.6;urinary bladder: 378.9" "Cell type enriched" "Detected in some" 184 "Plasma cells: 14426.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 409 "memory B-cell: 164.0;naive B-cell: 136.6" "Lineage enriched" "Detected in single" 446 "B-cells: 164.0" "Cell line enhanced" "Detected in some" "BEWO: 2.1;Daudi: 1.7;NB-4: 2.3;RPMI-8226: 1.7;SCLC-21H: 1.7;SH-SY5Y: 3.0;U-266/70: 1.3" "Immunoglobulin genes" NA NA 8500000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (2.12e-3)" "unprognostic (5.51e-2)" "unprognostic (1.05e-1)" "unprognostic (1.81e-3)" "unprognostic (1.72e-2)" "prognostic favorable (3.23e-5)" "unprognostic (7.43e-2)" "unprognostic (2.09e-1)" "unprognostic (1.95e-2)" "unprognostic (2.94e-2)" "unprognostic (2.94e-1)" "unprognostic (2.50e-1)" "prognostic unfavorable (1.65e-7)" "unprognostic (1.32e-1)" "unprognostic (2.16e-1)" "unprognostic (2.01e-1)" "unprognostic (6.96e-2)" 25.3 38.5 0.1 320.5 0.2 119.7 143.9 0.0 0.4 49.3 0.5 534.0 265.5 13.3 0.0 134.6 44.8 146.5 30.3 0.4 0.2 29.2 25.1 128.2 374.9 0.6 0.2 23.0 12.3 0.7 3.3 0.7 0.2 18.6 254.9 0.0 459.9 20.4 0.9 3.5 296.1 23.6 0.1 797.4 572.6 5.9 0.1 158.2 76.6 0.1 1294.8 378.9 34.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.3 2.3 0.0 0.0 0.0 0.0 1.0 1.7 0.0 0.0 1.7 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 1.3 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.1 164.0 0.2 0.0 0.1 136.6 0.3 0.1 0.3 0.0 0.0 0.2 0.0 24.4 0.1 0.2 0.0 0.4 0.4 0.2 0.6 0.2 0.2 0.1 0.1 0.3 0.0 0.0 0.0 0.0 78.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 5.4 16.3 0.0 1.3 0.0 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14426.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.4 0.0 IGHV3-48 ENSG00000211964 "Immunoglobulin heavy variable 3-48" P01763 14 106537810-106538344 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 516.4;lymphoid tissue: 858.8;stomach 1: 404.9" "Cell type enriched" "Detected in some" 100 "Plasma cells: 5878.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebral cortex: 1.3" "Group enriched" "Detected in some" 527 "memory B-cell: 187.1;naive B-cell: 97.5" "Lineage enriched" "Detected in single" 693 "B-cells: 187.1" "Cell line enhanced" "Detected in some" "SCLC-21H: 1.5;SH-SY5Y: 1.6" "Immunoglobulin genes" NA NA 49000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (9.19e-3)" "unprognostic (1.87e-2)" "unprognostic (5.12e-2)" "unprognostic (9.07e-3)" "unprognostic (1.77e-1)" "prognostic favorable (1.56e-5)" "unprognostic (1.23e-1)" "unprognostic (9.59e-2)" "unprognostic (2.65e-1)" "unprognostic (4.02e-2)" "unprognostic (2.64e-1)" "unprognostic (2.44e-1)" "prognostic unfavorable (4.88e-8)" "unprognostic (1.89e-1)" "unprognostic (1.25e-1)" "unprognostic (1.35e-1)" "unprognostic (2.15e-1)" 8.7 22.9 0.0 232.6 0.0 81.2 56.4 0.0 1.3 25.9 0.2 434.1 516.4 8.1 0.1 33.4 12.1 38.6 6.9 0.0 0.0 10.8 18.6 32.3 125.3 0.3 0.0 12.2 8.8 0.9 0.9 0.1 0.7 6.8 253.2 0.0 164.6 16.0 0.6 1.6 134.4 17.7 0.1 271.1 404.9 27.9 0.0 36.3 16.0 0.0 858.8 248.6 7.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.3 0.9 0.4 0.0 0.0 0.0 0.8 0.9 0.0 0.0 1.5 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.5 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 187.1 0.0 0.0 0.1 97.5 0.0 0.1 0.1 0.0 0.0 0.0 0.2 22.0 0.0 0.0 0.0 1.3 0.0 0.0 0.3 0.0 0.7 0.1 0.0 0.1 0.0 0.0 0.0 0.0 58.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 2.7 0.0 0.0 0.0 0.7 17.9 0.0 0.0 0.0 1.1 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5878.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 IGHV3-49 ENSG00000211965 "Immunoglobulin heavy variable 3-49" A0A0A0MS15 14 106556936-106557477 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 210.7;lymphoid tissue: 373.5;stomach 1: 182.3" "Cell type enriched" "Detected in some" 46 "Plasma cells: 717.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 187 "memory B-cell: 59.4;naive B-cell: 42.2" "Lineage enriched" "Detected in single" 219 "B-cells: 59.4" "Cell line enhanced" "Detected in single" "RPMI-8226: 1.0" "Immunoglobulin genes" NA NA 1600000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (7.16e-4)" "unprognostic (7.91e-3)" "unprognostic (2.50e-2)" "unprognostic (1.66e-2)" "unprognostic (2.12e-1)" "prognostic favorable (2.34e-6)" "unprognostic (4.47e-2)" "unprognostic (4.30e-2)" "unprognostic (7.00e-3)" "unprognostic (9.17e-2)" "unprognostic (2.18e-1)" "unprognostic (4.20e-2)" "prognostic unfavorable (1.43e-6)" "unprognostic (7.42e-2)" "unprognostic (2.79e-1)" "unprognostic (8.96e-2)" "unprognostic (3.00e-1)" 20.8 7.1 0.0 112.3 0.0 45.7 42.5 0.0 0.5 11.5 0.3 210.7 184.4 4.6 3.9 20.0 5.1 10.9 9.4 0.0 0.2 5.0 12.8 43.2 108.6 0.7 0.0 26.5 1.7 0.2 0.4 0.0 0.3 3.0 139.3 0.0 88.5 12.1 0.2 0.4 88.2 11.5 0.1 183.1 182.3 1.8 0.1 21.4 9.7 0.0 373.5 100.0 3.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.4 1.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 59.4 0.0 0.0 0.0 42.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 8.8 0.0 0.0 0.0 0.5 0.0 0.2 0.7 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.0 0.0 15.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.4 1.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 4.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 717.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 IGHV3-7 ENSG00000211938 "Immunoglobulin heavy variable 3-7" P01780 14 106062151-106062683 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 461.3;lymphoid tissue: 971.3" "Cell type enriched" "Detected in some" 255 "Plasma cells: 20463.1" "Cancer enhanced" "Detected in many" "stomach cancer: 18.5" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 147 "memory B-cell: 134.0;naive B-cell: 107.0" "Lineage enriched" "Detected in single" 163 "B-cells: 134.0" "Cell line enhanced" "Detected in some" "Daudi: 7.6;HL-60: 3.1;K-562: 3.0;NB-4: 3.0;RPMI-8226: 5.8;SH-SY5Y: 4.8;TIME: 2.9" "Immunoglobulin genes" NA NA 39000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.29e-2)" "unprognostic (5.57e-3)" "unprognostic (1.37e-2)" "prognostic favorable (1.47e-6)" "unprognostic (1.00e-2)" "unprognostic (2.74e-1)" "unprognostic (1.28e-1)" "unprognostic (5.46e-2)" "unprognostic (1.37e-1)" "unprognostic (1.66e-1)" "prognostic unfavorable (4.35e-5)" "unprognostic (5.18e-2)" "unprognostic (8.50e-2)" "unprognostic (1.63e-1)" "unprognostic (7.70e-2)" 47.8 10.1 0.7 50.1 1.0 71.1 202.7 0.3 0.8 87.4 0.6 461.3 154.1 37.7 8.2 17.8 13.4 37.0 2.2 0.2 0.4 17.6 20.3 56.4 102.5 1.6 2.8 24.7 4.8 2.9 1.8 0.3 2.3 9.2 303.5 0.0 265.5 22.9 1.3 9.6 206.0 3.6 3.9 610.4 230.4 13.2 0.4 0.0 21.1 0.1 971.3 42.9 14.8 1.3 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 3.1 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.0 0.0 0.0 0.0 0.0 3.0 0.5 0.0 0.0 0.4 2.6 5.8 0.0 0.0 2.3 4.8 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.7 0.0 1.2 1.6 0.0 0.1 0.0 0.6 0.0 0.4 0.8 0.2 0.1 0.0 0.2 134.0 0.2 0.2 0.3 107.0 0.1 0.1 0.1 0.1 0.2 0.6 0.2 12.6 0.7 1.0 0.3 0.8 0.2 0.4 1.6 2.8 2.3 3.9 0.4 1.3 0.0 0.0 0.0 0.0 80.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 30.5 0.0 5.3 0.0 0.0 0.0 4.4 31.1 0.0 0.0 0.0 2.2 1.9 0.0 0.0 0.0 0.2 0.0 1.6 0.0 0.3 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20463.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 1.0 0.0 0.0 7.4 0.0 0.5 0.0 IGHV5-51 ENSG00000211966 "Immunoglobulin heavy variable 5-51" A0A0C4DH38 14 106578744-106579236 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 245.7;lymphoid tissue: 547.1;salivary gland: 224.5;urinary bladder: 353.3" "Cell type enriched" "Detected in some" 87 "Plasma cells: 5993.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.8;Daudi: 3.7;K-562: 2.4;NB-4: 1.7;TIME: 3.3" HPA006014 Approved "Immunoglobulin genes" NA NA 2700000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA006014: " "unprognostic (2.03e-3)" "unprognostic (1.00e-1)" "unprognostic (3.21e-2)" "unprognostic (7.65e-3)" "unprognostic (1.80e-2)" "prognostic favorable (5.47e-4)" "unprognostic (2.40e-2)" "unprognostic (1.15e-1)" "unprognostic (3.92e-2)" "unprognostic (6.47e-2)" "unprognostic (2.49e-1)" "unprognostic (1.64e-1)" "prognostic unfavorable (3.31e-7)" "unprognostic (1.11e-1)" "unprognostic (1.05e-1)" "unprognostic (3.70e-1)" "unprognostic (1.17e-1)" 20.0 4.8 0.3 0.0 0.0 0.0 25.9 0.1 1.7 17.8 0.7 245.7 0.0 8.6 6.3 19.1 15.2 27.1 2.1 0.1 0.7 15.4 15.0 56.2 0.0 0.9 0.0 8.8 17.1 1.0 2.2 0.6 0.2 11.2 0.0 0.0 224.5 0.0 0.7 3.2 144.8 1.7 0.6 547.1 99.9 4.8 0.1 0.0 25.6 0.0 0.0 353.3 14.6 1.3 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 1.3 0.8 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.3 1.3 1.2 0.8 0.0 0.1 0.0 0.7 0.0 0.3 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.1 1.7 0.1 0.7 0.9 0.0 0.2 0.6 0.1 1.3 0.0 0.0 0.0 0.0 68.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 1.8 44.9 0.0 0.0 0.0 0.7 1.0 0.1 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5993.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.1 0.0 IGKC HCAK1 ENSG00000211592 "Immunoglobulin kappa constant" 2 88857161-88857683 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "intestine: 35196.7;lymphoid tissue: 63075.6" "Group enriched" "Detected in many" 12 "B-cells: 72318.1;Plasma cells: 96515.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 21 "memory B-cell: 39143.0;naive B-cell: 35081.5" "Lineage enriched" "Detected in all" 23 "B-cells: 39143.0" "Group enriched" "Detected in many" 6 "Daudi: 9909.1;U-266/70: 10337.6;U-266/84: 3927.9;U-698: 12154.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" CAB015377 Uncertain "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "CAB015377: AB_2251264" "prognostic favorable (6.59e-4)" "unprognostic (1.04e-2)" "unprognostic (3.54e-2)" "unprognostic (1.06e-2)" "unprognostic (8.82e-3)" "prognostic favorable (1.18e-4)" "unprognostic (1.24e-1)" "unprognostic (1.79e-1)" "unprognostic (3.19e-2)" "unprognostic (2.81e-3)" "unprognostic (2.82e-1)" "unprognostic (3.14e-1)" "prognostic unfavorable (2.17e-9)" "unprognostic (1.85e-1)" "unprognostic (2.47e-1)" "unprognostic (9.26e-2)" "unprognostic (1.59e-1)" 1025.4 2379.8 13.1 20500.0 13.3 6315.2 11287.7 11.3 33.6 3649.2 26.7 35196.7 24515.5 877.3 474.1 5708.4 1137.6 5995.3 810.4 11.4 16.7 1176.6 1580.5 5824.2 21356.1 25.1 18.2 2214.9 462.9 72.6 101.8 22.2 15.3 843.6 30618.3 4.0 19606.1 2123.2 32.9 250.8 17061.1 1259.7 43.5 26904.1 22740.5 1083.9 13.4 8576.0 2151.1 8.1 63075.6 24817.5 705.0 20.2 17.1 0.0 0.0 0.0 0.0 0.0 103.7 0.0 0.0 0.1 0.0 0.0 0.0 9909.1 15.3 0.0 1.0 22.2 0.0 0.0 0.0 510.2 0.0 30.9 0.0 0.0 0.0 67.8 29.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 65.8 0.4 0.0 0.0 18.3 83.2 28.8 0.0 0.0 16.7 56.4 1509.5 0.6 0.0 79.6 146.1 19.6 1.5 6.0 0.5 0.5 17.2 66.7 0.0 56.9 24.3 44.0 10337.6 3927.9 12154.4 0.0 28.9 0.0 47.5 55.6 31.6 24.6 11.2 21.7 39143.0 28.3 18.3 46.6 35081.5 15.2 16.8 65.2 24.1 29.1 1735.4 23.7 8567.0 13.1 13.3 11.3 33.6 11.4 16.7 25.1 18.2 15.3 43.5 13.4 20.2 58.6 336.5 1863.8 0.0 72318.1 0.0 189.2 0.0 2.2 0.0 8.8 7.0 5.7 163.0 88.5 0.0 0.0 48.0 452.1 39.8 3.9 0.0 2.8 0.7 0.3 72.8 77.8 1658.9 0.0 0.2 37.3 186.5 64.7 0.4 849.0 15.5 340.2 334.8 8.9 0.0 0.0 35.1 0.0 496.3 0.0 11.0 0.0 64.4 0.0 0.0 26.4 0.0 59.8 0.0 0.0 0.0 25.9 0.4 96515.7 193.2 0.3 45.2 12.4 0.0 0.0 3.7 38.4 0.3 0.2 5.9 0.0 49.4 6505.3 0.1 50.2 1.9 IGKJ1 J1 ENSG00000211597 "Immunoglobulin kappa joining 1" A0A0A0MT89 2 88861886-88861923 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "intestine: 3082.3;lymphoid tissue: 3301.5;salivary gland: 1202.6;stomach 1: 2816.8;urinary bladder: 1106.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 418 "memory B-cell: 38345.4;naive B-cell: 32121.1;plasmacytoid DC: 14778.6" "Group enriched" "Detected in all" 390 "B-cells: 38345.4;dendritic cells: 14778.6" "Cell line enriched" "Detected in many" 4 "U-266/70: 21925.7" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 57: B-cells - Immune response" 70.6 227.2 1.9 3301.5 1.5 424.8 363.1 1.3 9.2 71.7 5.0 1960.8 3082.3 41.6 0.0 278.0 18.1 157.4 31.0 3.2 2.2 31.7 92.0 382.5 839.3 3.4 2.4 127.7 50.3 2.0 0.0 6.3 2.9 50.4 1743.7 0.2 1202.6 16.4 6.9 8.8 2231.5 61.2 3.4 1516.0 2816.8 31.2 2.1 115.3 6.2 0.0 2770.1 1106.5 0.0 2.9 22.9 0.0 0.0 0.0 0.0 0.0 62.7 0.0 0.0 0.0 0.0 7.4 0.0 9.9 2.5 0.0 0.0 14.6 0.0 0.0 0.0 851.1 0.0 10.1 0.0 0.0 0.0 34.5 21.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 10.3 12.1 11.8 0.0 0.0 23.1 0.0 4365.8 0.0 0.0 10.3 18.7 0.0 0.0 4.9 0.0 0.0 31.0 0.0 0.0 9.7 2.4 34.6 21925.7 5461.9 93.7 0.0 6.3 0.0 48.3 44.8 22.7 19.1 17.9 25.4 38345.4 27.2 13.8 57.2 32121.1 20.1 20.9 68.0 38.9 26.9 14778.6 29.9 3897.0 1.9 1.5 1.3 9.2 3.2 2.2 3.4 2.4 2.9 3.4 2.1 2.9 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKJ2 J2 ENSG00000211596 "Immunoglobulin kappa joining 2" 2 88861525-88861563 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 2670.6;lymphoid tissue: 2226.1;salivary gland: 1187.7;stomach 1: 1719.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 50 "memory B-cell: 22200.6;naive B-cell: 20663.6" "Lineage enriched" "Detected in all" 52 "B-cells: 22200.6" "Group enriched" "Detected in many" 7 "HDLM-2: 213.9;RPMI-8226: 179.1" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" 67.9 154.0 0.6 1862.6 0.9 296.5 312.9 0.1 4.0 158.7 0.7 1762.7 2670.6 37.5 0.0 308.3 14.3 114.1 19.6 0.6 0.6 27.0 61.7 236.7 693.3 4.3 1.4 71.6 72.5 1.9 0.0 1.1 1.2 46.0 1364.3 0.0 1187.7 20.2 2.9 5.2 1974.3 28.2 1.5 1097.1 1719.7 44.8 0.9 73.5 5.1 0.0 2226.1 494.7 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 16.5 0.0 0.0 0.0 0.0 0.0 0.0 3.2 1.1 0.0 0.0 3.5 0.0 0.0 0.0 213.9 0.0 9.7 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 8.0 3.6 0.0 0.0 7.4 2.5 179.1 0.0 0.0 3.2 17.5 4.8 0.0 0.0 0.0 0.0 29.6 10.7 0.0 3.4 3.7 7.6 5.3 0.0 29.0 0.0 1.8 0.0 19.7 33.6 12.8 10.3 7.7 12.8 22200.6 15.0 8.1 23.3 20663.6 9.5 9.6 42.6 10.8 18.6 430.3 17.4 2451.2 0.6 0.9 0.1 4.0 0.6 0.6 4.3 1.4 1.2 1.5 0.9 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 IGKJ3 ENSG00000211595 "Immunoglobulin kappa joining 3" 2 88861221-88861258 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 1010.8;lymphoid tissue: 997.2;stomach 1: 710.1" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in many" 12 "spinal cord: 18.3" "Group enriched" "Detected in all" 26 "memory B-cell: 8663.4;naive B-cell: 7153.9" "Lineage enriched" "Detected in all" 28 "B-cells: 8663.4" "Group enriched" "Detected in some" 6 "HDLM-2: 105.2;RPMI-8226: 89.2;U-698: 41.2" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: HDLM-2 - Immune response" 15.1 19.6 0.8 886.7 0.7 115.0 111.2 0.3 1.3 19.2 0.5 587.3 1010.8 7.6 0.0 68.8 7.9 44.8 9.3 0.9 0.6 14.3 41.1 101.9 490.2 1.2 0.5 31.1 0.0 0.0 0.0 1.9 1.5 18.2 546.6 0.6 362.3 12.6 8.7 2.5 726.3 19.9 18.3 548.6 710.1 9.7 0.9 53.9 5.1 3.9 997.2 236.9 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 14.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 105.2 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 89.2 0.0 0.0 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 2.9 0.0 0.0 41.2 0.0 0.0 0.0 17.0 8.6 57.9 1.9 1.1 9.2 8663.4 3.0 3.3 5.9 7153.9 5.7 5.1 61.8 7.1 15.2 309.9 7.8 660.0 0.8 0.7 0.3 1.3 0.9 0.6 1.2 0.5 1.5 18.3 0.9 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKJ4 ENSG00000211594 "Immunoglobulin kappa joining 4" 2 88860886-88860922 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 3282.9;lymphoid tissue: 2905.5;stomach 1: 2295.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 42 "memory B-cell: 36413.7;naive B-cell: 27723.7" "Lineage enriched" "Detected in all" 48 "B-cells: 36413.7" "Cell line enhanced" "Detected in some" "BEWO: 16.9;Daudi: 23.5;HDLM-2: 58.4;RPMI-8226: 43.3;SH-SY5Y: 27.6;U-698: 25.7" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: HDLM-2 - Immune response" 80.0 268.7 0.6 2905.5 0.7 407.6 414.6 0.3 4.1 110.0 0.5 1844.1 3282.9 29.5 62.5 433.0 33.3 138.1 34.8 0.6 1.1 48.2 104.6 481.3 932.6 2.9 0.7 117.5 29.3 1.7 0.0 1.3 1.3 56.4 1849.6 0.3 1142.3 54.8 3.9 17.3 2184.0 78.1 2.6 1246.0 2295.9 39.7 1.8 113.5 11.4 0.0 2661.5 645.6 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 16.9 0.0 0.0 0.0 0.0 0.0 0.0 23.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 58.4 0.0 0.0 0.0 0.0 0.0 9.1 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 2.0 10.4 0.0 0.0 0.0 0.0 9.1 43.3 0.0 0.0 6.7 27.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 7.3 8.5 3.3 0.0 25.7 0.0 0.0 0.0 114.4 64.9 20.3 24.9 9.5 16.8 36413.7 15.8 15.2 32.5 27723.7 22.7 16.1 60.0 21.5 25.4 759.9 22.8 3519.3 0.6 0.7 0.3 4.1 0.6 1.1 2.9 0.7 1.3 2.6 1.8 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKJ5 ENSG00000211593 "Immunoglobulin kappa joining 5" 2 88860568-88860605 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 4 "intestine: 1221.3;lymphoid tissue: 1365.8;salivary gland: 643.7;stomach 1: 1066.6;urinary bladder: 436.6" "Cell type enriched" "Detected in single" 13 "B-cells: 1.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 24 "memory B-cell: 9254.1;naive B-cell: 8737.5" "Lineage enriched" "Detected in all" 25 "B-cells: 9254.1" "Cell line enriched" "Detected in some" 24 "U-698: 3392.4" NA NA "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "unprognostic (4.92e-2)" "unprognostic (2.57e-2)" "unprognostic (3.68e-2)" "unprognostic (9.30e-3)" "prognostic favorable (1.83e-4)" "unprognostic (1.12e-1)" "unprognostic (3.22e-1)" "prognostic unfavorable (5.49e-6)" "unprognostic (2.00e-2)" "unprognostic (4.25e-1)" "unprognostic (2.02e-1)" 25.2 42.2 0.5 1365.8 0.7 164.5 236.5 0.6 4.5 73.7 0.3 1194.4 1221.3 13.4 5.8 130.7 8.8 78.5 26.1 0.9 0.7 18.0 30.8 157.6 529.7 1.6 0.6 63.3 29.2 6.6 0.0 4.1 1.2 22.8 1171.9 0.0 643.7 17.1 0.0 5.8 1078.7 40.6 4.9 672.7 1066.6 12.4 0.7 61.5 4.3 0.0 1213.5 436.6 0.0 0.9 17.7 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.7 0.0 0.0 0.0 0.0 0.0 0.0 142.3 0.0 0.0 0.0 0.0 0.0 7.2 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 58.5 0.0 0.0 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 133.3 3.5 11.4 3.2 1.9 3392.4 0.0 8.1 0.0 3.3 10.1 10.2 3.8 1.3 2.2 9254.1 18.4 3.5 7.4 8737.5 9.5 3.4 9.4 7.6 3.4 373.6 8.8 1167.3 0.5 0.7 0.6 4.5 0.9 0.7 1.6 0.6 1.2 4.9 0.7 0.9 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV1-33 "IGKV133, O18" ENSG00000242076 "Immunoglobulin kappa variable 1-33" P01594 2 89266494-89268506 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Bence-Jones protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 1727.5;stomach 1: 627.3;urinary bladder: 623.3" "Cell type enriched" "Detected in some" 131 "Plasma cells: 2044.1" "Cancer enhanced" "Detected in many" "stomach cancer: 5.5" "Region enriched" "Detected in many" 7 "spinal cord: 12.0" "Group enriched" "Detected in some" 378 "memory B-cell: 369.6;naive B-cell: 441.5" "Lineage enriched" "Detected in many" 411 "B-cells: 441.5" "Cell line enhanced" "Detected in some" "RPMI-8226: 2.7;SCLC-21H: 9.1;SH-SY5Y: 8.8;U-251 MG: 3.5" HPA048721 Approved "Immunoglobulin genes" NA NA "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (1.76e-2)" "unprognostic (6.79e-2)" "unprognostic (1.52e-2)" "prognostic favorable (4.58e-5)" "unprognostic (5.06e-2)" "unprognostic (8.55e-3)" "unprognostic (2.31e-1)" "unprognostic (1.63e-2)" "unprognostic (2.57e-1)" "unprognostic (4.66e-1)" 50.5 21.9 0.1 266.2 0.5 139.5 320.5 0.6 1.0 129.8 0.4 471.5 296.2 20.7 2.8 106.2 33.4 187.2 23.2 0.2 1.6 36.7 37.9 130.4 529.5 0.4 1.0 37.0 8.3 1.9 2.7 0.4 0.7 18.7 511.9 0.2 476.4 127.7 0.7 2.5 175.9 14.5 12.0 820.8 627.3 13.5 0.2 381.9 53.9 0.2 1727.5 623.3 26.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.1 0.0 0.0 0.1 0.7 0.0 0.0 0.2 0.1 1.9 2.7 0.0 0.0 9.1 8.8 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.2 0.4 3.5 0.7 0.0 0.2 0.0 0.6 0.0 0.4 0.3 0.4 0.1 0.0 0.1 369.6 0.2 0.1 0.3 441.5 0.2 0.1 1.0 0.2 0.3 0.3 0.2 39.5 0.1 0.5 0.6 1.0 0.2 1.6 0.4 1.0 0.7 12.0 0.2 1.0 0.0 0.0 0.0 0.0 15.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 2.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2044.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 IGKV1-39 ENSG00000242371 "Immunoglobulin kappa variable 1-39" P01597 2 89319625-89320146 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 108.5;lymphoid tissue: 254.9;salivary gland: 151.2;stomach 1: 83.2" "Cell type enriched" "Detected in some" 151 "Plasma cells: 16225.1" "Cancer enhanced" "Detected in many" "stomach cancer: 13.4" "Not detected" "Not detected" "Group enriched" "Detected in many" 388 "memory B-cell: 1069.8;naive B-cell: 935.1" "Lineage enriched" "Detected in many" 415 "B-cells: 1069.8" "Cell line enriched" "Detected in some" 21 "Daudi: 194.2" HPA048721 Approved "Immunoglobulin genes" NA NA 8000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (1.76e-4)" "unprognostic (5.10e-3)" "unprognostic (4.71e-2)" "prognostic favorable (1.70e-5)" "unprognostic (2.38e-1)" "unprognostic (7.33e-2)" "unprognostic (1.78e-1)" "unprognostic (6.62e-6)" "unprognostic (1.19e-1)" "unprognostic (1.28e-1)" "unprognostic (4.27e-1)" "unprognostic (2.25e-1)" 10.9 9.1 0.0 54.7 0.1 14.2 17.7 0.0 0.1 21.8 0.0 108.5 70.5 5.7 0.0 11.6 12.5 14.3 1.5 0.2 0.0 10.9 6.8 27.2 36.5 0.0 0.0 1.8 3.2 0.0 0.5 0.0 0.2 4.2 13.3 0.0 151.2 0.9 0.2 1.3 74.4 1.2 0.0 254.9 83.2 0.3 0.0 5.9 31.0 0.0 42.5 17.5 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 194.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.5 1.8 0.0 9.0 0.0 0.0 0.0 0.9 1.0 0.7 0.3 0.3 0.3 1069.8 0.5 0.4 1.1 935.1 0.3 0.6 2.5 0.4 0.6 1.3 0.8 136.4 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 107.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 10.7 0.0 0.0 0.0 0.4 3.1 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16225.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 0.0 0.0 4.9 0.0 0.3 0.0 IGKV1-5 ENSG00000243466 "Immunoglobulin kappa variable 1-5" P01602 2 88947301-88947957 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 777.1;lymphoid tissue: 1459.2;urinary bladder: 945.2" "Cell type enriched" "Detected in some" 240 "Plasma cells: 39194.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 364 "memory B-cell: 859.0;naive B-cell: 860.5" "Lineage enriched" "Detected in many" 364 "B-cells: 860.5" "Cell line enhanced" "Detected in some" "Daudi: 4.0;HL-60: 2.4;RPMI-8226: 5.0;SCLC-21H: 2.9;SH-SY5Y: 4.5" HPA048721 Approved "Immunoglobulin genes" NA NA 8400000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (1.19e-4)" "unprognostic (1.26e-2)" "unprognostic (3.12e-3)" "unprognostic (5.00e-3)" "unprognostic (1.59e-2)" "prognostic favorable (3.47e-4)" "unprognostic (7.60e-2)" "unprognostic (2.84e-1)" "unprognostic (1.68e-1)" "unprognostic (3.32e-2)" "unprognostic (2.28e-1)" "unprognostic (3.58e-1)" "prognostic unfavorable (4.36e-8)" "unprognostic (1.14e-1)" "unprognostic (1.20e-1)" "unprognostic (8.27e-2)" "unprognostic (3.17e-2)" 35.8 82.0 0.2 639.7 0.2 115.4 233.9 0.1 1.6 115.8 0.6 777.1 528.7 17.1 2.0 146.2 86.9 124.8 18.7 0.1 0.5 36.2 32.0 125.3 387.2 1.0 0.2 60.8 10.8 0.5 3.0 0.4 0.3 16.7 745.0 0.0 392.2 34.8 0.9 3.2 429.7 24.4 1.3 915.4 456.3 11.5 0.2 155.3 58.4 0.0 1459.2 945.2 28.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 2.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.4 1.6 0.5 0.0 0.0 0.3 1.0 5.0 0.0 0.0 2.9 4.5 0.2 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.4 0.7 0.4 0.6 0.1 0.4 0.0 0.6 0.0 0.7 1.2 1.3 0.5 0.2 0.4 859.0 2.3 0.3 1.0 860.5 0.2 0.3 1.4 0.4 0.6 0.7 0.6 113.5 0.2 0.2 0.1 1.6 0.1 0.5 1.0 0.2 0.3 1.3 0.2 0.5 0.0 0.0 0.6 0.0 163.2 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.7 0.0 0.0 0.0 7.0 89.7 0.0 0.0 0.0 0.7 3.3 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39194.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.1 0.0 0.0 11.8 0.0 0.2 0.0 IGKV1D-39 ENSG00000251546 "Immunoglobulin kappa variable 1D-39" P04432 2 89862482-89862981 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 2922.1;lymphoid tissue: 6491.8;stomach 1: 2259.8" "Cell type enriched" "Detected in some" 298 "Plasma cells: 7890.2" "Cancer enhanced" "Detected in many" "stomach cancer: 12.1" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 226 "memory B-cell: 470.5;naive B-cell: 733.0" "Lineage enriched" "Detected in many" 275 "B-cells: 733.0" "Group enriched" "Detected in some" 36 "Daudi: 731.4;U-698: 516.7" HPA048721 Approved "Immunoglobulin genes" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (1.88e-4)" "unprognostic (4.70e-2)" "unprognostic (2.14e-3)" "prognostic favorable (5.99e-5)" "unprognostic (3.84e-1)" "unprognostic (4.34e-2)" "unprognostic (1.28e-1)" "unprognostic (9.06e-2)" "unprognostic (2.96e-2)" "unprognostic (3.92e-1)" "unprognostic (1.84e-1)" 147.3 181.1 0.6 1609.8 0.8 466.1 990.4 0.5 4.2 369.0 2.1 2922.1 2055.2 80.0 52.5 611.3 132.1 629.8 87.5 0.4 2.0 82.3 171.8 685.1 1968.9 2.6 0.8 214.9 26.5 3.5 5.5 1.3 3.6 80.9 2261.1 0.4 1229.7 148.4 2.3 33.2 1255.9 88.7 4.2 1712.0 2259.8 27.6 1.3 770.5 209.3 0.0 6491.8 1816.1 46.9 2.5 0.3 0.0 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 0.0 0.0 0.0 731.4 0.5 0.0 0.0 2.1 0.0 0.0 0.0 0.3 0.0 3.2 0.0 0.0 0.0 5.9 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.0 2.3 6.6 2.4 0.0 0.0 1.0 2.9 10.3 0.0 0.0 11.1 17.3 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 1.8 2.5 0.0 0.1 516.7 0.0 1.6 0.0 0.5 0.4 0.8 0.6 0.2 0.4 470.5 0.3 0.3 0.4 733.0 0.5 0.2 2.6 0.8 0.4 0.4 0.3 47.6 0.6 0.8 0.5 4.2 0.4 2.0 2.6 0.8 3.6 4.2 1.3 2.5 0.0 0.0 0.0 0.0 26.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7890.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 14.0 0.0 0.0 0.0 IGKV2-28 ENSG00000244116 "Immunoglobulin kappa variable 2-28" A0A075B6P5 2 89221698-89222461 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1044.6;lymphoid tissue: 1735.3" "Cell type enriched" "Detected in some" 92 "Plasma cells: 1868.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 13 "naive B-cell: 11.1" "Lineage enriched" "Detected in single" 13 "B-cells: 11.1" "Cell line enhanced" "Detected in some" "BEWO: 2.4;Daudi: 2.8;HL-60: 3.6;K-562: 2.0;NB-4: 2.7;RPMI-8226: 4.5;SCLC-21H: 2.1;SH-SY5Y: 1.7" "Immunoglobulin genes" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.03e-2)" "unprognostic (1.73e-2)" "unprognostic (1.34e-1)" "prognostic favorable (3.32e-4)" "unprognostic (2.12e-2)" "unprognostic (6.32e-3)" "unprognostic (3.14e-1)" "unprognostic (3.71e-2)" "unprognostic (5.21e-2)" "unprognostic (2.64e-2)" 36.2 40.2 0.2 402.4 0.2 180.2 425.2 0.1 1.1 56.6 0.9 1044.6 756.7 38.2 4.9 662.7 29.0 130.8 22.3 0.1 0.3 46.2 40.2 157.6 584.6 0.6 0.9 87.9 19.5 3.8 3.3 0.5 0.3 21.1 709.6 0.1 732.4 95.0 1.8 7.1 425.6 23.9 0.8 1207.7 530.0 161.9 0.2 167.6 84.8 0.0 1735.3 494.1 30.7 0.9 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 2.7 0.4 0.0 0.0 0.0 1.1 4.5 0.0 0.4 2.1 1.7 0.3 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.9 0.9 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.4 0.1 0.0 0.0 0.1 0.2 0.1 0.0 0.2 11.1 0.2 0.1 0.8 0.1 0.0 0.4 0.1 0.0 0.2 0.2 0.1 1.1 0.1 0.3 0.6 0.9 0.3 0.8 0.2 0.9 0.0 0.0 0.0 0.0 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1868.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 20.3 0.0 0.0 0.0 IGKV3-11 ENSG00000241351 "Immunoglobulin kappa variable 3-11" P04433 2 89027171-89027731 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1373.3;lymphoid tissue: 2812.9;urinary bladder: 1822.6" "Cell type enriched" "Detected in some" 129 "Plasma cells: 27475.3" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in some" 9 "spinal cord: 19.8" "Group enriched" "Detected in many" 292 "memory B-cell: 1729.8;naive B-cell: 1401.2" "Lineage enriched" "Detected in many" 323 "B-cells: 1729.8" "Cell line enhanced" "Detected in some" "BEWO: 3.0;Daudi: 2.0;SCLC-21H: 3.7;SH-SY5Y: 4.6" HPA047702 Approved "Immunoglobulin genes" NA NA 18000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "unprognostic (3.97e-3)" "unprognostic (1.17e-2)" "unprognostic (3.51e-2)" "unprognostic (1.91e-2)" "unprognostic (2.70e-2)" "prognostic favorable (1.36e-5)" "unprognostic (2.02e-1)" "unprognostic (3.20e-1)" "unprognostic (5.73e-2)" "unprognostic (2.86e-2)" "unprognostic (1.70e-1)" "unprognostic (2.34e-1)" "prognostic unfavorable (2.26e-8)" "unprognostic (5.93e-2)" "unprognostic (2.48e-1)" "unprognostic (1.22e-1)" "unprognostic (1.07e-1)" 45.8 60.5 0.4 733.2 0.3 189.1 385.3 0.2 2.1 136.2 0.6 1373.3 701.6 32.1 11.5 143.5 34.0 253.5 18.9 0.2 0.6 44.4 55.2 227.4 575.7 0.6 0.7 120.8 13.7 1.9 3.2 0.9 0.9 30.1 1090.9 0.1 496.0 60.9 1.2 14.2 536.0 59.5 19.8 1100.0 788.6 22.2 0.3 261.9 88.8 0.9 2812.9 1822.6 33.4 1.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.7 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 1.2 0.4 0.0 0.0 0.4 1.8 1.5 0.0 0.0 3.7 4.6 0.4 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.7 0.7 0.6 1.8 0.3 0.1 0.0 1.4 0.0 1.9 1.3 1.2 2.0 0.2 0.7 1729.8 0.8 0.6 1.6 1401.2 0.8 0.8 5.3 0.9 1.1 1.2 1.3 186.7 0.4 0.3 0.2 2.1 0.2 0.6 0.6 0.7 0.9 19.8 0.3 1.0 0.0 0.0 0.5 0.0 211.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 82.6 0.0 0.0 0.0 2.5 1.9 0.0 0.0 0.0 0.1 0.0 1.9 0.0 0.7 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27475.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.4 0.0 0.0 62.0 0.0 0.3 0.0 IGKV3-20 ENSG00000239951 "Immunoglobulin kappa variable 3-20" P01619 2 89142574-89143160 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 3080.6;lymphoid tissue: 5246.5" "Cell type enriched" "Detected in some" 138 "Plasma cells: 52154.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 329 "memory B-cell: 1602.7;naive B-cell: 1222.4" "Lineage enriched" "Detected in many" 373 "B-cells: 1602.7" "Group enriched" "Detected in many" 215 "U-266/70: 3769.9;U-266/84: 1732.3" HPA047702 Approved "Immunoglobulin genes" NA NA 20000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "prognostic favorable (1.86e-4)" "unprognostic (4.16e-2)" "unprognostic (1.64e-2)" "unprognostic (1.97e-2)" "unprognostic (1.13e-1)" "prognostic favorable (9.01e-4)" "unprognostic (1.43e-1)" "unprognostic (3.43e-1)" "unprognostic (1.37e-1)" "unprognostic (3.93e-3)" "unprognostic (8.44e-2)" "unprognostic (1.97e-1)" "prognostic unfavorable (1.07e-6)" "unprognostic (7.35e-2)" "unprognostic (5.08e-1)" "unprognostic (6.64e-2)" "unprognostic (2.70e-2)" 104.8 56.4 0.9 1791.2 0.9 380.3 736.4 0.5 4.2 326.9 2.6 3080.6 1714.2 59.0 7.8 302.1 105.2 637.2 55.7 0.5 1.6 106.2 113.5 454.0 2815.6 2.1 8.4 153.5 32.8 5.8 9.6 1.8 1.4 56.1 2731.8 0.2 1270.5 224.5 3.3 13.4 1355.8 82.8 10.4 2699.1 1412.9 24.7 1.2 671.5 224.3 1.8 5246.5 1644.0 70.0 1.5 2.5 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.5 0.0 0.0 2.3 0.0 0.0 0.0 0.5 0.0 2.1 0.0 0.0 0.0 6.1 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 2.0 5.9 2.8 0.0 0.0 3.0 6.0 10.4 0.0 0.0 7.7 12.8 1.4 0.0 0.1 0.0 0.0 0.8 4.4 0.0 2.0 1.5 4.3 3769.9 1732.3 1.8 0.0 2.3 0.0 4.0 1.2 0.7 0.7 0.4 0.8 1602.7 0.8 0.6 3.5 1222.4 0.4 0.7 4.2 0.8 1.0 0.9 0.8 196.9 0.9 0.9 0.5 4.2 0.5 1.6 2.1 8.4 1.4 10.4 1.2 1.5 0.1 3.2 1.3 0.0 376.9 0.0 0.0 0.0 5.2 0.0 0.1 0.1 0.0 4.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 9.4 0.0 0.0 0.0 55.3 124.4 0.0 1.3 0.0 3.6 5.0 0.1 0.0 0.0 0.1 0.0 5.3 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.2 0.0 52154.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 3.0 0.0 0.0 26.7 0.0 0.2 0.0 IGKV4-1 "B3, IGKV41" ENSG00000211598 "Immunoglobulin kappa variable 4-1" P06312 2 88885397-88886153 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1805.7;lymphoid tissue: 3169.0" "Cell type enriched" "Detected in some" 219 "Plasma cells: 46306.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 588 "memory B-cell: 3036.3;naive B-cell: 3070.9" "Lineage enriched" "Detected in all" 591 "B-cells: 3070.9" "Cell line enhanced" "Detected in some" "Daudi: 14.9;RPMI-8226: 10.4;SH-SY5Y: 6.9;U-266/70: 7.5" "Immunoglobulin genes" NA NA 8500000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (6.41e-5)" "unprognostic (9.19e-2)" "unprognostic (4.29e-3)" "unprognostic (5.42e-3)" "unprognostic (2.08e-2)" "prognostic favorable (8.25e-4)" "unprognostic (1.79e-2)" "unprognostic (1.12e-1)" "unprognostic (3.32e-1)" "unprognostic (3.71e-3)" "unprognostic (1.56e-1)" "unprognostic (3.29e-1)" "prognostic unfavorable (2.52e-6)" "unprognostic (1.99e-1)" "unprognostic (1.01e-1)" "unprognostic (6.29e-2)" "unprognostic (1.19e-1)" 55.9 296.3 0.4 1054.1 0.9 342.1 665.2 0.4 3.4 145.2 2.4 1805.7 1769.7 46.8 19.4 195.7 41.3 188.2 51.9 0.4 1.2 35.0 76.1 302.3 816.8 1.9 0.8 86.5 28.3 2.5 2.8 1.0 3.5 43.9 1318.2 0.1 701.8 89.6 1.0 8.6 1023.0 66.4 3.6 972.3 1125.7 125.7 0.7 405.1 51.0 0.1 3169.0 758.2 19.4 1.5 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 14.9 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.9 0.0 1.7 0.0 0.0 0.0 3.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.6 3.6 0.3 0.0 0.0 1.4 2.2 10.4 0.0 0.0 4.0 6.9 2.3 0.0 0.0 0.0 0.0 0.7 2.6 0.0 0.8 1.1 1.0 7.5 0.2 0.8 0.0 1.2 0.0 3.9 3.2 5.1 1.6 0.9 1.7 3036.3 1.9 1.1 2.8 3070.9 2.1 1.3 2.4 1.6 2.4 2.3 1.7 344.9 0.4 0.9 0.4 3.4 0.4 1.2 1.9 0.8 3.5 3.6 0.7 1.5 0.0 0.0 0.0 0.0 210.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 8.0 0.0 0.0 0.0 17.0 40.2 0.0 0.0 0.0 2.2 2.8 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 3.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 46306.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 15.7 0.0 0.1 0.0 IGLC1 IGLC ENSG00000211675 "Immunoglobulin lambda constant 1" 22 22895375-22895834 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 3264.2;lymphoid tissue: 5586.9;stomach 1: 2335.3" "Group enriched" "Detected in some" 4 "Alveolar cells type 2: 37.3;granulocytes: 15.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 743 "memory B-cell: 5729.2;naive B-cell: 5821.4" "Lineage enriched" "Detected in all" 749 "B-cells: 5821.4" "Cell line enriched" "Detected in many" 5 "U-266/70: 600.3" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 11: Alveolar cells - Smell perception" 132.3 163.1 2.2 1208.8 1.9 641.9 903.4 1.7 7.0 190.8 4.4 3038.0 3264.2 63.1 2.1 535.0 113.2 640.0 104.5 1.7 2.2 148.2 114.7 470.6 2372.4 3.9 1.7 135.6 69.8 8.0 13.2 1.9 2.2 71.5 2133.6 0.7 2047.0 124.0 4.9 28.8 1389.9 78.0 2.6 3332.0 2335.3 23.7 2.3 873.2 224.5 0.0 5586.9 1948.8 79.3 3.4 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.4 0.0 0.0 0.0 1.0 0.0 1.9 0.2 0.0 0.0 6.5 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 9.1 0.0 0.0 1.1 10.2 2.0 0.0 0.0 2.3 8.9 33.4 0.0 0.0 6.3 11.1 1.4 0.0 0.0 0.0 0.0 0.3 2.5 0.0 1.3 4.3 2.6 600.3 119.9 36.5 0.0 3.5 0.0 4.2 7.7 2.0 3.7 1.7 2.9 5729.2 3.8 2.5 6.0 5821.4 0.9 2.2 7.6 2.8 4.8 5.2 3.4 897.2 2.2 1.9 1.7 7.0 1.7 2.2 3.9 1.7 2.2 2.6 2.3 3.4 0.0 6.4 37.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 15.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 IGLC2 IGLC ENSG00000211677 "Immunoglobulin lambda constant 2" P0DOY2 22 22900976-22901437 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Bence-Jones protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 9734.6;lymphoid tissue: 19988.7;stomach 1: 10849.9" "Group enriched" "Detected in many" 40 "B-cells: 24632.2;Plasma cells: 18795.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 36 "memory B-cell: 11361.1;naive B-cell: 10650.3" "Lineage enriched" "Detected in all" 37 "B-cells: 11361.1" "Group enriched" "Detected in many" 190 "RPMI-8226: 62032.1;U-266/70: 102644.1;U-266/84: 83511.6" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (5.76e-5)" "unprognostic (2.29e-2)" "unprognostic (4.54e-3)" "unprognostic (1.46e-2)" "unprognostic (4.02e-2)" "prognostic favorable (1.14e-4)" "unprognostic (1.96e-2)" "unprognostic (7.52e-2)" "unprognostic (7.15e-2)" "unprognostic (7.69e-3)" "unprognostic (2.83e-1)" "unprognostic (4.41e-2)" "prognostic unfavorable (4.47e-9)" "unprognostic (2.00e-1)" "unprognostic (3.43e-1)" "unprognostic (1.19e-1)" "unprognostic (1.45e-1)" 386.6 782.7 7.7 3871.2 6.2 2741.4 2183.6 4.6 14.9 815.5 11.4 8217.0 9734.6 194.3 207.0 1690.0 231.5 2091.8 318.3 4.6 5.7 301.6 382.3 1442.8 5543.4 11.1 5.0 540.2 112.7 16.8 31.0 7.5 6.6 264.0 5055.4 0.7 5934.2 384.9 8.6 74.2 5290.6 306.2 6.6 7090.0 10849.9 256.0 5.4 2071.4 491.7 0.6 19988.7 6482.1 176.7 10.7 120.6 0.0 0.0 0.0 0.0 0.0 29.1 0.0 0.0 0.0 0.0 0.0 0.0 221.4 12.0 0.0 0.0 61.9 0.0 0.0 0.0 30.5 0.0 7.7 0.0 0.0 0.0 19.2 343.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.9 64.7 0.0 0.0 70.1 27.7 52.3 0.0 0.0 45.3 436.2 62032.1 0.0 0.0 46.7 45.7 5.6 43.0 17.3 0.0 17.7 57.2 11.7 0.0 38.9 23.4 78.2 102644.1 83511.6 298.8 0.7 21.9 0.7 9.9 18.6 5.6 5.8 3.0 5.7 11361.1 5.8 4.5 10.9 10650.3 3.5 4.7 118.0 5.8 8.7 303.3 6.5 2385.6 7.7 6.2 4.6 14.9 4.6 5.7 11.1 5.0 6.6 6.6 5.4 10.7 4.1 32.1 121.0 0.0 24632.2 0.0 0.3 0.0 1.2 0.0 16.1 3.0 3.9 44.3 8.1 0.0 0.0 0.3 8.0 28.0 0.0 0.0 0.0 0.0 0.1 86.3 62.5 222.4 0.0 0.0 0.3 42.5 14.8 0.0 65.6 0.0 222.8 539.9 2.1 0.0 0.0 21.5 0.0 134.5 0.0 0.0 0.0 8.5 0.0 0.0 11.4 0.0 15.5 0.0 0.0 0.0 20.6 0.0 18795.5 0.0 0.0 1.4 1.5 0.0 0.0 0.2 10.2 0.0 0.0 2.8 0.0 0.1 538.6 0.0 23.7 0.0 IGLC3 IGLC ENSG00000211679 "Immunoglobulin lambda constant 3 (Kern-Oz+ marker)" P0DOY3 22 22906342-22906803 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Bence-Jones protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 4115.7;lymphoid tissue: 8175.8;stomach 1: 4130.0;urinary bladder: 3726.3" "Group enriched" "Detected in many" 35 "B-cells: 12202.8;Plasma cells: 5357.3;T-cells: 3582.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 34 "memory B-cell: 7254.6;naive B-cell: 6119.2" "Lineage enriched" "Detected in all" 37 "B-cells: 7254.6" "Cell line enriched" "Detected in many" 15 "RPMI-8226: 10741.3" "CAB000050, CAB016533" Supported "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "CAB000050: , CAB016533: AB_629719" "prognostic favorable (2.32e-4)" "unprognostic (1.18e-2)" "unprognostic (4.35e-3)" "unprognostic (4.54e-2)" "unprognostic (8.41e-2)" "prognostic favorable (3.33e-4)" "unprognostic (5.45e-2)" "unprognostic (4.59e-2)" "unprognostic (8.77e-2)" "prognostic favorable (4.58e-4)" "unprognostic (9.71e-2)" "unprognostic (2.31e-1)" "prognostic unfavorable (1.04e-9)" "unprognostic (1.21e-1)" "unprognostic (2.52e-1)" "unprognostic (1.37e-1)" "unprognostic (5.97e-2)" 156.2 550.9 2.6 2377.2 2.7 840.6 1388.6 1.4 9.1 220.4 7.1 4115.7 4046.3 115.2 33.2 508.5 88.0 707.7 63.7 1.3 2.8 178.6 171.7 1081.6 2745.8 7.2 1.4 247.8 47.6 7.0 19.0 3.2 2.0 134.0 2268.4 0.3 2264.0 177.1 5.8 20.7 2373.2 113.9 3.4 4261.5 4130.0 55.4 2.1 426.9 232.0 0.9 8175.8 3726.3 111.5 6.4 0.6 0.0 0.0 0.0 0.0 0.0 16.6 0.0 0.0 0.0 0.0 0.0 0.0 60.1 0.7 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 18.3 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 338.0 0.0 0.0 10.8 15.0 2.8 0.0 0.0 700.2 9.3 10741.3 0.0 0.0 16.6 25.1 4.4 20.8 0.0 0.0 4.9 0.8 11.1 0.0 6.3 7.2 5.0 88.0 103.4 36.1 1.2 5.3 0.5 6.4 9.1 3.9 6.0 2.0 27.3 7254.6 5.1 3.6 6.9 6119.2 2.6 3.3 60.7 4.3 4.6 195.3 4.7 1415.5 2.6 2.7 1.4 9.1 1.3 2.8 7.2 1.4 2.0 3.4 2.1 6.4 2.0 22.4 97.3 0.0 12202.8 0.0 0.7 0.0 0.0 0.0 5.4 0.5 15.3 8.6 3.7 0.0 0.0 0.2 8.8 5.0 0.0 0.0 0.0 0.0 0.1 7.4 12.2 54.8 0.0 0.0 0.0 22.1 5.6 0.1 47.9 0.0 195.9 127.7 0.2 0.0 0.0 3.5 0.0 23.1 0.0 0.0 0.0 5.6 0.0 0.0 2.0 0.0 2.1 0.0 0.0 0.0 3.1 0.0 5357.3 0.2 0.0 1.1 2.2 0.0 0.0 0.0 4.2 0.0 0.0 0.8 0.0 0.1 3582.0 0.0 6.3 0.9 IGLJ3 ENSG00000211678 "Immunoglobulin lambda joining 3" 22 22904850-22905025 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 7 "intestine: 552.2;lymphoid tissue: 227.6;salivary gland: 149.1;stomach 1: 462.5;urinary bladder: 147.8" "Group enriched" "Detected in some" 44 "B-cells: 4.5;Plasma cells: 4.3" "Group enriched" "Detected in some" 13 "colorectal cancer: 5.1;endometrial cancer: 10.3" "Region enhanced" "Detected in single" "cerebral cortex: 1.5" "Group enriched" "Detected in many" 24 "memory B-cell: 1223.9;naive B-cell: 1139.6" "Lineage enriched" "Detected in many" 25 "B-cells: 1223.9" "Group enriched" "Detected in some" 7 "Daudi: 53.6;REH: 69.6;U-266/70: 42.8;U-266/84: 22.5" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 57: B-cells - Immune response" "unprognostic (1.19e-1)" "unprognostic (2.06e-3)" "unprognostic (2.05e-1)" "unprognostic (1.37e-1)" "unprognostic (5.00e-1)" 5.7 29.4 0.4 212.4 0.3 37.4 32.5 0.1 1.5 9.7 0.4 130.1 552.2 3.2 0.0 40.0 4.0 32.7 3.1 0.1 0.1 2.9 9.9 41.7 132.1 0.4 0.2 31.1 1.9 0.0 0.0 0.1 0.1 9.6 71.4 0.0 149.1 1.6 0.0 1.5 205.9 6.1 0.0 207.6 462.5 6.1 0.1 23.2 0.8 0.0 227.6 147.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 53.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 69.6 2.5 6.7 0.0 0.0 0.8 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.5 1.0 42.8 22.5 4.3 0.0 0.0 0.0 0.8 1.6 0.7 0.9 0.3 4.3 1223.9 0.8 0.5 1.3 1139.6 0.4 0.5 8.5 0.6 1.2 49.2 0.8 193.9 0.4 0.3 0.1 1.5 0.1 0.1 0.4 0.2 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLV1-40 ENSG00000211653 "Immunoglobulin lambda variable 1-40" P01703 22 22409766-22410282 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 1291.5;stomach 1: 1287.4" "Cell type enriched" "Detected in some" 358 "Plasma cells: 43406.7" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in some" "cerebral cortex: 3.0" "Group enriched" "Detected in some" 496 "memory B-cell: 666.4;naive B-cell: 576.7" "Lineage enriched" "Detected in many" 532 "B-cells: 666.4" "Cell line enhanced" "Detected in some" "Daudi: 3.5;RPMI-8226: 2.2;SH-SY5Y: 3.4;TIME: 2.3" "Immunoglobulin genes" NA NA 2300000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.64e-3)" "unprognostic (4.68e-3)" "unprognostic (3.88e-2)" "unprognostic (3.37e-3)" "unprognostic (9.60e-3)" "prognostic favorable (5.74e-6)" "unprognostic (2.39e-2)" "unprognostic (1.53e-1)" "unprognostic (8.43e-2)" "unprognostic (5.51e-2)" "unprognostic (1.06e-1)" "unprognostic (2.18e-1)" "prognostic unfavorable (5.44e-6)" "unprognostic (1.51e-1)" "unprognostic (1.57e-1)" "unprognostic (1.34e-1)" "unprognostic (4.57e-2)" 43.4 13.0 0.8 203.5 0.5 114.3 138.5 0.1 3.0 68.1 1.1 553.8 551.6 14.8 0.6 125.4 21.5 236.0 15.2 0.2 0.2 28.8 28.3 115.4 282.5 0.3 0.2 56.6 10.0 1.1 3.4 0.6 0.6 46.1 336.7 4.2 413.8 19.7 1.2 3.1 287.2 14.3 0.2 1029.8 1287.4 7.2 0.3 179.2 61.2 0.0 1291.5 464.8 19.5 1.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.3 1.0 1.1 0.0 0.0 0.2 0.8 2.2 0.0 0.0 1.3 3.4 0.1 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.4 0.7 0.7 1.1 1.1 0.8 0.0 0.3 0.0 0.4 0.7 0.2 0.3 0.1 0.6 666.4 0.3 0.3 0.6 576.7 0.1 0.2 1.2 0.3 0.3 0.6 0.4 53.7 0.8 0.5 0.1 3.0 0.2 0.2 0.3 0.2 0.6 0.2 0.3 1.0 0.0 0.0 0.0 0.0 121.0 0.0 0.0 0.0 2.2 0.0 0.4 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 1.2 8.0 0.0 0.0 0.0 28.6 64.2 0.0 0.0 0.0 1.8 0.9 0.0 0.0 0.0 0.1 0.0 1.6 0.0 0.7 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 43406.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.0 0.0 7.4 0.0 0.1 0.0 IGLV1-44 ENSG00000211651 "Immunoglobulin lambda variable 1-44" P01699 22 22380766-22381347 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 589.7;lymphoid tissue: 1918.7;stomach 1: 534.3" "Cell type enriched" "Detected in some" 108 "Plasma cells: 12023.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 840 "memory B-cell: 968.8;naive B-cell: 850.4" "Lineage enriched" "Detected in many" 894 "B-cells: 968.8" "Cell line enhanced" "Detected in some" "Daudi: 21.3;RPMI-8226: 5.5;SCLC-21H: 4.1;U-698: 15.2" "Immunoglobulin genes" NA NA 4000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.88e-3)" "unprognostic (1.51e-2)" "unprognostic (2.40e-2)" "unprognostic (7.23e-3)" "unprognostic (4.81e-3)" "prognostic favorable (4.71e-5)" "unprognostic (2.18e-2)" "unprognostic (1.90e-1)" "unprognostic (1.05e-1)" "unprognostic (3.10e-2)" "unprognostic (1.64e-1)" "unprognostic (2.28e-1)" "prognostic unfavorable (6.55e-8)" "unprognostic (1.85e-1)" "unprognostic (1.98e-1)" "unprognostic (6.48e-2)" "unprognostic (5.49e-2)" 33.9 2.0 0.1 297.2 0.0 133.4 110.2 0.0 0.8 14.3 0.0 378.7 589.7 11.8 0.0 80.1 19.5 78.7 17.5 0.0 0.0 18.7 17.1 122.2 519.5 1.3 0.2 15.3 3.6 0.0 2.6 0.0 0.4 13.8 263.1 0.0 273.0 9.4 0.7 2.4 236.5 21.4 0.0 608.7 534.3 11.6 0.1 117.8 35.1 0.0 1918.7 240.5 16.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 5.5 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.2 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 968.8 0.0 0.0 0.7 850.4 0.0 0.0 0.0 0.0 0.1 1.0 0.1 100.0 0.1 0.0 0.0 0.8 0.0 0.0 1.3 0.2 0.4 0.0 0.1 0.8 0.0 0.0 0.6 0.0 111.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 2.7 0.0 0.0 0.0 3.5 48.4 0.0 0.0 0.0 0.7 0.6 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12023.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.2 0.0 0.3 0.0 IGLV1-47 ENSG00000211648 "Immunoglobulin lambda variable 1-47" P01700 22 22357739-22358260 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 706.6;lymphoid tissue: 1804.0;stomach 1: 625.5" "Cell type enriched" "Detected in some" 114 "Plasma cells: 10777.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 638 "memory B-cell: 1518.1;naive B-cell: 819.6" "Lineage enriched" "Detected in many" 828 "B-cells: 1518.1" "Cell line enhanced" "Detected in some" "HL-60: 2.1;RH-30: 2.1;RPMI-8226: 4.2;SCLC-21H: 2.7;SH-SY5Y: 2.4;U-698: 7.1" "Immunoglobulin genes" NA NA 3000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (5.19e-3)" "unprognostic (2.69e-2)" "unprognostic (1.11e-2)" "unprognostic (1.33e-2)" "unprognostic (1.26e-1)" "prognostic favorable (2.66e-4)" "unprognostic (4.44e-2)" "unprognostic (1.09e-1)" "unprognostic (5.69e-2)" "unprognostic (3.14e-2)" "unprognostic (2.28e-1)" "unprognostic (2.64e-1)" "prognostic unfavorable (5.12e-8)" "unprognostic (5.00e-3)" "unprognostic (1.62e-1)" "unprognostic (7.08e-2)" "unprognostic (1.15e-2)" 36.0 216.0 0.6 323.0 0.4 162.3 200.5 0.4 2.3 82.1 0.7 706.6 704.7 23.8 3.0 163.7 21.3 112.7 27.2 0.2 0.5 23.2 31.8 126.7 689.2 2.6 0.4 43.5 8.9 4.9 2.1 0.5 1.2 22.5 531.5 0.2 526.6 70.2 0.7 4.7 332.8 34.7 0.5 813.7 625.5 9.8 0.4 260.1 34.1 0.0 1804.0 367.0 10.3 2.4 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.0 0.0 0.0 1.4 0.4 0.0 0.0 0.7 2.1 4.2 0.0 0.0 2.7 2.4 0.5 0.0 0.0 0.1 0.0 0.3 0.9 0.0 0.0 0.0 0.1 0.6 0.0 7.1 0.0 0.9 0.0 0.7 1.2 0.5 0.7 0.1 0.5 1518.1 0.7 0.6 1.0 819.6 0.3 0.6 0.6 0.5 0.5 1.8 0.6 159.6 0.6 0.4 0.4 2.3 0.2 0.5 2.6 0.4 1.2 0.5 0.4 2.4 0.0 0.0 0.0 0.0 94.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5.7 0.0 0.0 0.0 1.7 29.0 0.0 0.0 0.0 0.7 1.7 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 10777.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.3 0.0 IGLV2-14 ENSG00000211666 "Immunoglobulin lambda variable 2-14" P01704 22 22758700-22759218 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 2622.2;lymphoid tissue: 5374.9;stomach 1: 2530.1" "Cell type enriched" "Detected in some" 179 "Plasma cells: 58316.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 50 "memory B-cell: 3655.3;naive B-cell: 2657.4" "Lineage enriched" "Detected in all" 58 "B-cells: 3655.3" "Cell line enriched" "Detected in many" 5 "RPMI-8226: 22672.4" "Immunoglobulin genes" NA NA 2200000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (3.23e-4)" "unprognostic (9.05e-3)" "unprognostic (1.18e-2)" "unprognostic (7.20e-3)" "unprognostic (2.00e-2)" "prognostic favorable (2.21e-4)" "unprognostic (3.69e-1)" "unprognostic (1.97e-1)" "unprognostic (7.99e-2)" "unprognostic (1.83e-2)" "unprognostic (9.11e-2)" "unprognostic (4.97e-1)" "prognostic unfavorable (5.74e-7)" "unprognostic (1.15e-1)" "unprognostic (1.33e-1)" "unprognostic (1.42e-1)" "unprognostic (2.87e-2)" 83.9 192.1 0.8 754.9 1.7 357.8 749.8 0.5 6.4 119.7 3.8 2622.2 2470.7 47.8 20.7 245.2 49.0 442.1 45.2 0.6 1.0 54.3 102.1 399.3 3320.0 1.6 0.6 75.3 52.1 4.5 5.6 1.2 1.0 71.0 1074.1 0.1 797.3 119.4 2.7 21.3 1262.7 62.0 1.4 1580.6 2530.1 13.9 1.3 586.1 116.5 0.5 5374.9 1165.2 35.1 2.1 0.2 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.4 0.0 0.0 9.8 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 5.8 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 4453.2 0.0 0.0 8.7 8.0 1.7 0.0 0.0 4.9 3.7 22672.4 0.0 0.0 11.8 11.1 0.4 17.3 0.0 0.0 7.1 0.0 5.1 0.0 4.1 5.7 1.1 20.4 37.7 1.4 12.1 1.7 5.0 3.9 5.3 1.7 47.1 1.0 28.8 3655.3 9.6 53.9 3.3 2657.4 1.4 12.7 11.6 62.5 2.4 2.2 2.1 451.3 0.8 1.7 0.5 6.4 0.6 1.0 1.6 0.6 1.0 1.4 1.3 2.1 0.0 0.0 0.0 0.0 324.1 0.0 0.0 0.0 1.2 0.0 0.3 0.3 0.0 2.8 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 14.7 0.0 0.0 0.0 9.9 121.8 0.0 0.0 0.0 1.4 1.7 0.0 0.0 0.0 0.3 0.0 3.5 0.0 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 58316.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 36.6 0.0 0.8 0.0 IGLV3-21 ENSG00000211662 "Immunoglobulin lambda variable 3-21" P80748 22 22711689-22713203 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 1812.1;urinary bladder: 773.9" "Cell type enriched" "Detected in some" 59 "Plasma cells: 5013.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 339 "memory B-cell: 432.0;naive B-cell: 224.7" "Lineage enriched" "Detected in single" 445 "B-cells: 432.0" "Cell line enriched" "Detected in some" 103 "REH: 282.7" "Immunoglobulin genes" NA NA 4700000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 14: REH - Unknown function" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.75e-3)" "unprognostic (6.04e-3)" "unprognostic (4.21e-2)" "unprognostic (2.59e-3)" "unprognostic (4.06e-3)" "prognostic favorable (3.26e-7)" "unprognostic (1.63e-1)" "unprognostic (1.78e-1)" "unprognostic (1.53e-1)" "unprognostic (5.30e-2)" "unprognostic (3.86e-1)" "unprognostic (2.35e-1)" "prognostic unfavorable (9.54e-8)" "unprognostic (7.83e-2)" "unprognostic (1.88e-1)" "unprognostic (2.67e-1)" "unprognostic (7.52e-2)" 17.6 63.4 0.3 321.9 0.2 248.2 120.7 0.1 1.6 110.0 1.6 357.4 350.4 12.9 0.5 63.1 10.2 120.4 10.8 0.1 0.2 21.5 36.4 108.6 272.7 1.0 0.1 35.6 5.7 0.7 1.4 0.4 0.4 16.8 230.8 0.0 260.8 20.2 0.5 2.3 150.7 9.0 0.3 421.0 504.5 14.4 0.3 171.6 19.9 0.0 1812.1 773.9 17.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 2.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.4 0.5 0.2 0.0 0.0 282.7 1.8 2.0 0.0 0.0 1.6 1.8 0.1 0.3 0.0 0.0 0.0 0.0 2.2 0.0 0.3 0.5 0.5 0.5 0.1 0.2 0.0 0.2 0.0 0.2 0.2 0.1 0.1 0.0 0.1 432.0 0.1 0.1 0.3 224.7 0.1 0.1 0.9 0.1 0.1 0.2 0.1 36.6 0.3 0.2 0.1 1.6 0.1 0.2 1.0 0.1 0.4 0.3 0.3 1.3 0.0 0.0 0.0 0.0 84.4 0.0 0.0 0.0 4.6 0.0 0.1 0.0 0.1 2.8 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 4.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.4 20.4 0.0 0.0 0.0 3.3 2.5 0.1 0.0 0.0 0.0 0.0 1.3 0.0 4.7 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5013.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 1.2 0.0 0.0 1.8 0.0 0.2 0.0 IGLV3-25 ENSG00000211659 "Immunoglobulin lambda variable 3-25" P01717 22 22686726-22687271 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 2440.7;stomach 1: 1015.7" "Cell type enriched" "Detected in some" 41 "Plasma cells: 17441.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 45 "memory B-cell: 545.0;naive B-cell: 794.2" "Lineage enriched" "Detected in many" 53 "B-cells: 794.2" "Cell line enhanced" "Detected in some" "HL-60: 2.6;RPMI-8226: 2.7;SCLC-21H: 4.6;SH-SY5Y: 5.1" HPA003285 Approved "Immunoglobulin genes" NA NA 3200000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA003285: AB_1079122" "prognostic favorable (5.55e-4)" "unprognostic (8.28e-2)" "unprognostic (4.28e-3)" "unprognostic (2.89e-2)" "unprognostic (2.88e-2)" "prognostic favorable (1.43e-4)" "unprognostic (1.92e-2)" "unprognostic (1.05e-1)" "unprognostic (1.87e-1)" "unprognostic (1.98e-2)" "unprognostic (4.86e-2)" "unprognostic (3.45e-1)" "prognostic unfavorable (3.78e-7)" "unprognostic (1.25e-1)" "unprognostic (4.78e-1)" "unprognostic (2.16e-1)" "unprognostic (1.72e-1)" 56.8 163.2 0.2 293.2 0.2 243.2 430.9 0.1 1.7 151.9 1.3 847.4 338.9 20.8 2.1 161.5 49.8 177.1 29.8 0.2 0.3 17.1 45.7 870.5 1024.7 1.8 0.2 21.8 14.5 1.7 1.7 0.5 0.6 18.9 467.5 0.0 532.3 116.5 0.7 2.4 228.9 34.1 0.4 543.5 1015.7 59.8 0.5 155.9 23.1 0.0 2440.7 779.6 20.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.6 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.1 0.0 0.0 1.7 0.4 1.7 0.0 0.0 1.6 1.5 2.7 0.0 0.0 4.6 5.1 0.3 0.0 0.0 0.0 0.0 0.0 1.4 0.0 1.0 0.1 0.8 1.8 0.2 0.7 0.0 1.3 0.0 0.8 0.4 0.3 0.7 0.1 0.2 545.0 0.4 0.1 0.5 794.2 0.2 0.1 14.9 0.3 0.6 0.3 0.3 76.5 0.2 0.2 0.1 1.7 0.2 0.3 1.8 0.2 0.6 0.4 0.5 0.6 0.0 0.0 0.0 0.0 84.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.7 0.0 0.0 0.0 1.9 40.8 0.0 0.0 0.0 0.4 1.8 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17441.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 417.4 0.0 0.0 0.1 0.0 0.0 3.5 0.0 0.0 0.0 IGSF22 "FLJ37794, IGFN2" ENSG00000179057 "Immunoglobulin superfamily member 22" Q8N9C0 11 18704312-18726230 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "skin 1: 1.0" "Cell type enhanced" "Detected in many" "Collecting duct cells: 23.9;Distal tubular cells: 21.5" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB026459, HPA037851" Uncertain Approved Mitochondria NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB026459: , HPA037851: " "unprognostic (4.05e-2)" "unprognostic (3.65e-2)" "unprognostic (2.34e-2)" "unprognostic (1.84e-1)" "unprognostic (1.23e-1)" "unprognostic (8.93e-2)" "unprognostic (1.02e-1)" "unprognostic (8.38e-2)" "unprognostic (8.70e-2)" "unprognostic (4.24e-2)" "unprognostic (1.99e-4)" "unprognostic (9.35e-2)" "unprognostic (3.72e-4)" "unprognostic (2.87e-1)" "unprognostic (2.18e-1)" "unprognostic (3.43e-1)" "unprognostic (7.94e-3)" 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.3 0.1 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.2 1.0 0.1 0.0 0.0 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.3 0.2 0.3 0.1 0.1 0.1 0.0 0.3 0.2 0.6 0.0 0.5 0.3 2.9 2.4 4.7 1.4 0.6 1.3 7.5 5.3 1.7 0.0 3.1 23.9 0.0 0.0 1.0 1.5 21.5 3.3 1.4 5.3 1.2 0.9 3.6 0.0 3.2 4.3 0.0 0.7 2.0 5.8 2.5 0.7 0.4 0.4 1.5 1.7 1.7 5.8 8.2 0.3 1.0 4.6 1.5 0.6 0.0 0.0 0.7 0.5 2.1 1.5 0.3 9.5 2.6 0.7 0.3 4.0 0.3 2.2 6.1 0.9 0.0 0.5 1.0 0.0 0.4 0.7 1.7 0.0 2.9 3.1 2.8 8.4 IGSF8 "CD316, CD81P3, EWI2, PGRL" ENSG00000162729 "Immunoglobulin superfamily member 8" Q969P0 1 160091340-160098943 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 155.3" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 219.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 177.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011917, HPA075970" Approved Supported Vesicles NA NA 280000 "Cluster 32: T-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 38: Extravillous trophoblasts - Unknown function" Vesicles "HPA011917: AB_1851536, HPA075970: " "unprognostic (4.08e-1)" "prognostic unfavorable (7.32e-4)" "unprognostic (1.30e-2)" "unprognostic (9.31e-2)" "unprognostic (1.46e-1)" "unprognostic (1.20e-1)" "unprognostic (1.71e-1)" "unprognostic (1.01e-3)" "unprognostic (1.63e-2)" "unprognostic (1.65e-1)" "unprognostic (1.09e-1)" "unprognostic (1.63e-1)" "unprognostic (2.31e-1)" "unprognostic (2.60e-2)" "unprognostic (2.35e-1)" "unprognostic (3.74e-3)" "unprognostic (1.75e-3)" 21.9 19.1 97.9 14.0 119.0 3.7 26.7 91.7 130.7 25.7 39.9 31.7 26.5 19.8 22.7 22.3 28.2 12.3 29.0 106.0 82.4 35.5 53.9 23.6 16.8 109.3 97.8 37.5 31.8 15.8 30.7 11.2 99.9 26.4 10.4 14.3 30.1 18.2 12.4 50.3 28.5 7.0 98.6 24.2 27.5 33.4 94.7 13.6 28.6 7.1 8.9 20.3 25.0 155.3 26.8 15.7 20.1 51.3 11.6 7.3 42.9 12.9 16.8 26.9 25.0 17.9 17.9 39.0 47.1 18.8 23.4 50.3 8.2 18.9 3.8 47.3 15.0 5.1 17.3 31.2 19.2 13.5 41.7 9.0 37.7 17.5 5.6 19.0 5.6 42.0 7.0 21.8 6.3 25.4 33.8 31.3 42.4 55.6 24.8 19.1 10.3 28.7 24.7 27.4 8.5 36.6 14.8 47.4 177.6 17.5 33.7 17.3 5.8 11.8 25.4 21.5 10.6 59.6 71.2 17.7 41.6 5.3 31.6 0.1 5.2 2.4 22.0 7.2 19.5 19.6 18.0 25.6 5.8 22.7 23.4 25.7 1.4 9.2 4.7 9.9 26.9 11.3 97.9 119.0 91.7 130.7 106.0 82.4 109.3 97.8 99.9 98.6 94.7 155.3 12.2 9.6 3.3 18.3 21.1 43.7 30.2 43.1 26.2 55.6 28.0 29.2 3.3 17.2 16.7 38.6 10.4 32.8 15.1 36.1 5.9 34.2 3.8 12.0 7.2 7.8 19.9 7.4 65.3 12.4 219.7 22.4 6.6 26.4 10.2 12.2 13.2 28.8 14.9 65.6 43.8 24.7 44.7 4.3 16.2 1.1 16.8 8.5 42.7 9.4 51.5 75.7 10.3 9.0 107.2 20.6 39.5 15.8 20.0 22.0 47.6 15.8 6.0 11.8 6.6 39.8 15.3 4.0 6.6 21.0 62.4 69.4 19.5 13.6 32.6 26.0 IL1RN "ICIL-1RA, IL-1RN, IL1F3, IL1RA, IRAP, MGC10430" ENSG00000136689 "Interleukin 1 receptor antagonist" P18510 2 113107214-113134016 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "esophagus: 1969.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 184.4;Hofbauer cells: 306.0;Langerhans cells: 292.6;Squamous epithelial cells: 469.7;Suprabasal keratinocytes: 336.6;Urothelial cells: 464.9" "Cancer enhanced" "Detected in all" "head and neck cancer: 92.7" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 4 "classical monocyte: 63.8;myeloid DC: 61.7;neutrophil: 240.2" "Group enriched" "Detected in many" 694 "dendritic cells: 61.7;granulocytes: 240.2;monocytes: 63.8" "Cell line enhanced" "Detected in some" "A-431: 59.1;HaCaT: 112.3;RT4: 106.6;THP-1: 27.3" "Not detected" "Not detected" "HPA001482, CAB009633" Enhanced Approved Nucleoplasm,Centrosome,Cytosol "Secreted to blood" NA NA 291000 45000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "Centrosome, Cytosol" "CAB009633: AB_2125576, HPA001482: AB_1078437" "unprognostic (3.85e-3)" "unprognostic (3.96e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (3.00e-4)" "unprognostic (2.21e-1)" "unprognostic (3.63e-2)" "unprognostic (3.15e-2)" "unprognostic (2.55e-1)" "unprognostic (4.46e-2)" "unprognostic (9.54e-2)" "prognostic unfavorable (6.85e-4)" "unprognostic (5.59e-3)" "prognostic unfavorable (2.66e-6)" "unprognostic (2.05e-1)" "prognostic unfavorable (8.23e-4)" "unprognostic (4.25e-2)" "unprognostic (1.03e-1)" 13.0 2.1 0.2 46.7 0.4 233.3 9.0 0.4 1.3 278.1 1.1 4.4 10.7 2.5 2.9 1969.7 2.1 17.0 2.5 0.3 0.3 1.6 248.5 20.1 1.4 0.4 0.5 0.9 1.8 2.0 2.3 21.1 0.8 2.4 4.0 0.0 287.1 7.5 0.8 128.6 8.8 3.9 0.8 14.7 45.5 6.4 1.3 5.2 6.4 3.0 311.7 185.7 465.0 0.6 59.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 7.9 0.0 0.2 0.0 0.6 0.2 0.2 0.0 1.1 112.3 0.0 3.3 0.0 0.1 0.0 0.3 0.0 17.3 0.0 0.3 20.3 0.0 14.3 0.7 0.0 2.0 0.0 0.0 0.3 0.3 0.0 0.5 0.1 14.7 0.0 13.2 0.0 0.0 0.1 0.1 0.0 106.6 0.0 0.0 0.1 0.8 0.1 0.0 0.0 27.3 0.3 1.4 0.0 0.7 0.1 0.6 0.1 0.2 10.3 10.5 0.3 0.0 63.8 1.9 0.0 27.7 0.0 0.1 0.0 0.0 61.7 0.1 0.1 0.1 240.2 0.0 13.7 0.8 0.1 19.8 0.2 0.4 0.4 1.3 0.3 0.3 0.4 0.5 0.8 0.8 1.3 0.6 1.7 6.4 7.7 0.0 4.1 184.4 81.3 151.8 56.9 0.0 4.9 3.4 0.4 11.5 60.6 3.7 0.0 1.8 0.2 6.5 0.0 27.5 34.8 7.8 1.4 4.8 0.0 3.2 0.3 28.0 2.9 11.0 44.4 23.6 10.1 0.0 3.3 53.0 306.0 0.0 0.2 1.1 6.1 39.8 292.6 93.3 0.6 111.1 24.9 0.0 22.6 0.0 2.1 0.5 0.2 149.9 0.1 0.4 2.8 58.4 9.3 0.2 20.2 0.0 0.0 0.3 3.8 0.8 0.2 469.7 336.6 4.5 3.3 0.0 3.2 464.9 IL36B "FIL1, FILI-(ETA), IL-1F8, IL-1H2, IL1-ETA, IL1F8, IL1H2, MGC126880, MGC126882" ENSG00000136696 "Interleukin 36 beta" Q9NZH7 2 113022089-113052867 "Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 2.2;lymphoid tissue: 3.8;skin 1: 8.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "head and neck cancer: 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 21 "GAMG: 71.8;U-87 MG: 73.3" "Not detected" "Not detected" HPA035664 Uncertain "Secreted to blood" NA NA 15300 "Cluster 31: Skin - Epidermis development" "Cluster 11: RPE1 & U-87MG - Synaptic function" "HPA035664: AB_10669672" "unprognostic (8.45e-2)" "unprognostic (1.62e-1)" "unprognostic (3.56e-2)" "unprognostic (1.06e-1)" "unprognostic (3.77e-2)" "unprognostic (2.40e-3)" "unprognostic (2.05e-1)" "unprognostic (7.10e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 71.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.4 0.0 1.4 0.0 0.0 0.0 0.0 73.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IL37 "FIL1, FIL1(ZETA), FIL1Z, IL-1F7, IL-1H4, IL-1RP1, IL1F7" ENSG00000125571 "Interleukin 37" Q9NZH6 2 112912971-112918882 "Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skin 1: 136.8" "Cell type enriched" "Detected in some" 26 "Ionocytes: 73.2" "Cancer enriched" "Detected in some" 6 "lung cancer: 6.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 2.7;PC-3: 5.9;RT4: 3.2" "HPA054371, HPA057950" Uncertain Supported Nucleoplasm,Vesicles "Secreted to blood" NA NA 76700 "Cluster 48: NK-cells - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Vesicles" "HPA054371: AB_2682465, HPA057950: AB_2683561" "unprognostic (1.79e-1)" "unprognostic (1.29e-1)" "unprognostic (1.64e-1)" "unprognostic (3.71e-5)" "unprognostic (1.11e-1)" "unprognostic (2.58e-2)" "unprognostic (1.09e-2)" "unprognostic (1.28e-2)" "unprognostic (9.54e-2)" "unprognostic (8.26e-3)" "unprognostic (3.95e-2)" "unprognostic (1.66e-1)" "unprognostic (8.92e-2)" "unprognostic (1.35e-2)" 0.1 0.0 0.0 0.2 0.0 0.2 16.7 0.0 0.1 0.0 0.0 0.5 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.0 0.0 0.1 0.4 136.8 0.1 0.0 0.0 0.0 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.4 0.1 0.0 0.0 0.1 0.2 2.7 0.2 0.2 0.2 0.3 0.0 0.2 0.1 0.2 0.1 0.1 0.4 0.8 0.1 0.0 1.0 0.1 0.4 0.0 0.0 0.1 0.0 0.0 0.3 0.6 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.8 0.2 0.2 5.9 0.0 0.0 0.0 0.0 3.2 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.1 0.1 0.2 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 73.2 0.0 0.4 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.1 0.0 2.8 0.0 0.1 0.0 0.0 0.0 IQGAP3 ENSG00000183856 "IQ motif containing GTPase activating protein 3" Q86VI3 1 156525405-156572604 "Plasma proteins, Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 15.5" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 11.2;Late spermatids: 26.6;Undifferentiated cells: 7.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" "HPA030142, HPA030143" Uncertain Approved "Nucleoplasm,Nucleoli rim,Mitotic chromosome" Yes Yes "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoli rim" "Nucleoplasm, Mitotic chromosome" "HPA030142: AB_10600108, HPA030143: AB_10601104" "unprognostic (9.99e-3)" "unprognostic (5.24e-2)" "unprognostic (3.26e-1)" "unprognostic (1.55e-3)" "unprognostic (1.52e-1)" "unprognostic (4.69e-3)" "prognostic unfavorable (8.94e-6)" "unprognostic (1.86e-3)" "unprognostic (1.72e-1)" "unprognostic (1.98e-1)" "unprognostic (6.35e-3)" "unprognostic (1.03e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (4.46e-2)" "unprognostic (1.53e-1)" "unprognostic (6.30e-2)" "unprognostic (6.81e-2)" 0.7 0.7 0.2 2.2 0.4 15.5 0.6 0.0 0.6 1.1 0.2 4.1 6.6 0.5 1.1 5.2 0.2 0.7 0.4 0.5 0.1 0.6 0.6 1.6 1.6 0.9 0.4 0.1 0.2 0.1 0.1 2.8 0.9 0.4 5.0 0.0 1.0 0.1 0.3 3.7 5.7 2.9 0.0 0.8 4.6 3.8 0.6 3.4 0.2 0.0 2.2 0.9 2.1 0.4 59.2 28.4 25.6 18.1 1.6 4.0 12.4 43.1 28.3 41.0 36.6 32.4 52.5 5.2 15.6 25.2 21.6 54.6 17.5 22.1 36.3 0.1 15.7 7.8 62.6 16.1 0.2 9.7 0.1 1.2 2.5 34.3 50.0 10.0 24.1 12.5 16.1 8.1 30.2 31.2 5.7 13.7 18.6 57.7 28.0 18.9 28.8 6.1 10.4 20.3 16.3 25.2 38.7 44.9 14.9 29.8 35.8 25.6 16.8 36.8 43.7 30.4 51.4 4.0 2.1 2.4 12.4 15.1 42.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.0 0.2 0.4 0.0 0.6 0.5 0.1 0.9 0.4 0.9 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.4 1.3 0.1 0.4 0.6 0.0 1.4 1.3 1.0 2.8 0.1 0.0 0.0 2.2 0.1 3.9 0.0 0.3 6.5 0.5 0.7 0.6 1.2 6.5 0.7 0.0 3.6 0.9 11.2 1.4 0.0 4.4 2.5 0.4 3.9 0.0 0.2 3.7 0.0 1.3 6.1 26.6 0.3 1.9 0.0 1.0 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.0 0.5 0.4 0.8 0.4 0.0 0.0 0.0 0.0 1.4 6.4 2.6 3.6 1.0 0.8 0.2 0.3 7.4 0.4 IRF6 "LPS, OFC6, VWS, VWS1" ENSG00000117595 "Interferon regulatory factor 6" O14896 1 209785617-209806175 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 95.4;skin 1: 114.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 387.2;Basal prostatic cells: 253.9;Basal squamous epithelial cells: 217.9;Squamous epithelial cells: 251.9;Suprabasal keratinocytes: 552.4;Urothelial cells: 290.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "cerebellum: 10.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 61.9;HaCaT: 210.7;HBEC3-KT: 80.5;hTCEpi: 170.1;hTERT-HME1: 82.2;RT4: 78.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA063121, HPA076162" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" Cytosol Nucleoplasm "HPA063121: AB_2684942, HPA076162: AB_2686780" "unprognostic (2.59e-1)" "unprognostic (1.79e-3)" "unprognostic (1.74e-1)" "unprognostic (7.80e-2)" "unprognostic (1.33e-2)" "unprognostic (4.94e-3)" "unprognostic (1.46e-1)" "unprognostic (1.36e-1)" "unprognostic (7.82e-2)" "unprognostic (1.46e-1)" "unprognostic (1.74e-3)" "unprognostic (2.03e-1)" "prognostic favorable (0.00e+0)" "unprognostic (2.70e-1)" "unprognostic (2.66e-2)" "unprognostic (2.14e-1)" "unprognostic (4.42e-2)" 1.6 11.4 1.6 3.2 1.5 2.8 35.9 10.9 1.8 21.6 5.2 27.1 26.9 5.9 49.3 95.4 21.7 10.8 29.7 1.7 1.4 17.0 33.3 8.8 0.9 1.9 2.9 1.9 19.7 26.4 6.5 20.4 1.9 32.4 31.5 2.4 39.0 26.4 0.5 114.0 25.0 2.0 2.1 2.1 24.8 2.9 2.3 20.3 17.1 2.7 23.0 40.5 46.8 1.2 61.9 0.0 0.0 0.0 0.4 0.0 20.9 0.1 0.5 0.1 0.3 13.6 20.7 0.0 0.1 0.1 0.0 210.7 0.0 80.5 0.0 0.0 1.3 0.1 0.2 0.0 0.2 0.0 0.2 0.1 170.1 0.1 82.2 0.0 3.7 0.0 0.1 0.2 0.0 8.3 0.0 0.3 1.2 17.0 0.2 0.0 0.0 0.3 7.7 78.8 18.7 6.1 1.4 34.1 1.9 3.8 24.1 0.3 0.0 0.0 0.1 0.0 0.3 0.8 15.8 0.1 0.2 0.0 0.2 0.0 0.0 0.4 0.6 0.2 0.4 0.1 0.1 0.2 0.1 0.1 0.4 0.2 0.0 0.1 0.0 0.0 0.0 0.2 1.6 1.5 10.9 1.8 1.7 1.4 1.9 2.9 1.9 2.1 2.3 1.2 1.9 16.0 10.4 0.3 1.0 387.2 253.9 154.0 217.9 0.1 47.2 33.3 26.0 32.9 70.4 35.0 0.0 94.2 1.3 95.5 27.4 36.7 1.1 120.2 9.5 6.0 59.9 0.4 0.0 19.2 25.4 4.5 53.0 121.7 2.5 0.0 1.1 35.9 8.3 0.0 0.1 74.9 38.7 1.0 30.1 0.7 0.6 2.3 35.6 1.9 1.0 6.5 0.0 0.0 0.0 49.2 43.8 0.0 2.5 153.9 49.5 11.9 82.1 0.6 0.0 0.4 7.4 8.2 3.7 251.9 552.4 161.6 2.5 0.7 44.5 290.3 ITPRID1 "CCDC129, FLJ38344" ENSG00000180347 "ITPR interacting domain containing 1" Q6ZRS4 7 31514071-31658720 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "brain: 15.9;salivary gland: 5.3" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-2 OS: 1.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA024103 Uncertain Uncertain Nucleoplasm NA NA "Cluster 70: Brain - Nervous system development" "Cluster 9: U-2 OS - Unknown function" "Cluster 43: Cardiomyocytes - Nuclear processes" Nucleoplasm "HPA024103: AB_1846132" "unprognostic (1.11e-2)" "unprognostic (1.39e-1)" "unprognostic (1.57e-1)" "unprognostic (1.78e-5)" "unprognostic (9.72e-3)" "unprognostic (1.78e-1)" "unprognostic (3.89e-2)" "unprognostic (6.42e-3)" "unprognostic (1.01e-1)" "unprognostic (5.77e-2)" "unprognostic (1.77e-2)" "unprognostic (1.10e-1)" "unprognostic (1.99e-1)" "unprognostic (1.53e-1)" 0.1 0.0 2.7 0.1 3.9 0.1 1.6 11.0 0.4 1.7 0.0 0.5 1.1 0.6 0.1 0.0 0.0 0.1 0.0 0.7 9.7 0.1 0.0 0.0 0.0 4.8 15.9 0.0 0.1 0.0 0.1 0.0 9.2 0.1 0.1 0.1 5.3 0.0 0.0 2.3 0.5 0.6 1.4 0.0 0.4 1.3 13.2 0.0 0.0 0.0 0.1 0.0 0.0 5.7 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 1.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.7 3.9 11.0 0.4 0.7 9.7 4.8 15.9 9.2 1.4 13.2 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 JCHAIN "IGCJ, IGJ, JCH" ENSG00000132465 "Joining chain of multimeric IgA and IgM" P01591 4 70655541-70681817 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 3028.0;intestine: 7979.6;stomach 1: 5916.2" "Cell type enriched" "Detected in many" 16 "Plasma cells: 101294.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 121 "memory B-cell: 4173.0;naive B-cell: 2555.1;plasmacytoid DC: 3578.1" "Group enriched" "Detected in all" 137 "B-cells: 4173.0;dendritic cells: 3578.1" "Cell line enhanced" "Detected in many" "Daudi: 3953.8;Karpas-707: 2117.6;RPMI-8226: 4469.2;U-266/70: 8794.0;U-266/84: 3519.2;U-698: 4949.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB034436, HPA044132" Enhanced "Secreted to blood" NA NA 2200000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 9: Intestine - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "CAB034436: AB_2233368, HPA044132: AB_2678826" "prognostic favorable (1.81e-6)" "unprognostic (1.45e-3)" "unprognostic (7.44e-3)" "unprognostic (1.82e-2)" "unprognostic (4.23e-2)" "prognostic favorable (7.56e-7)" "unprognostic (2.37e-2)" "unprognostic (2.70e-2)" "unprognostic (6.30e-2)" "unprognostic (2.64e-3)" "unprognostic (3.36e-1)" "unprognostic (7.34e-2)" "prognostic unfavorable (1.40e-4)" "unprognostic (3.43e-1)" "unprognostic (3.03e-2)" "unprognostic (2.22e-1)" "unprognostic (1.96e-1)" 130.2 76.6 0.7 1089.0 0.8 76.3 3028.0 0.4 3.0 205.2 3.1 7979.6 6145.8 94.2 25.0 654.4 115.0 492.4 45.6 0.4 1.4 43.3 116.8 620.2 1033.5 1.9 1.0 183.5 78.3 2.1 2.0 2.4 0.8 90.2 6426.5 0.3 2420.5 258.4 4.2 13.2 4277.1 200.3 7.0 819.4 5916.2 40.0 0.8 155.3 19.4 0.8 1746.7 1059.4 11.6 2.8 8.9 0.0 0.0 0.0 0.0 0.0 15.5 8.2 1.5 0.1 0.1 0.0 0.0 3953.8 3.3 12.7 0.1 6.6 0.0 0.0 0.6 2.1 0.0 3.3 0.0 0.0 0.0 3.3 9.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 5.4 2117.6 0.1 0.0 6.1 14.9 4.9 0.0 0.0 4.8 2.6 4469.2 0.0 0.0 3.3 15.7 3.7 2.6 2.7 0.0 0.8 6.8 3.9 9.9 11.8 4.9 6.3 8794.0 3519.2 4949.0 2.1 5.2 1.2 25.1 7.5 2.6 4.0 1.5 19.1 4173.0 2.5 3.8 6.6 2555.1 2.1 2.1 28.3 4.5 2.5 3578.1 2.6 1310.4 0.7 0.8 0.4 3.0 0.4 1.4 1.9 1.0 0.8 7.0 0.8 2.8 3.0 22.4 101.3 0.0 6154.9 0.0 28.2 0.0 8.6 0.0 11.7 1.9 2.2 15.7 8.1 0.0 0.0 0.1 700.0 5.1 0.0 0.0 0.5 0.0 0.1 38.1 7.3 139.0 0.0 0.0 0.1 48.8 228.8 0.0 79.5 0.1 66.4 24.6 0.3 0.0 0.0 5.3 0.0 35.8 0.0 0.3 0.0 42.0 0.0 0.0 3.9 0.0 6.2 0.0 0.0 0.0 5.1 0.0 101294.9 32.7 0.0 5.4 3.6 0.0 0.0 0.6 88.4 1.4 0.3 24.3 0.0 0.3 1487.8 0.0 3.5 0.6 JUP "CTNNG, DP3, DPIII, PDGB, PKGB" ENSG00000173801 "Junction plakoglobin" P14923 17 41754604-41786931 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Cancer-related genes, Cardiomyopathy, Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 952.2;skin 1: 932.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 315.9;Pancreatic endocrine cells: 356.2;Squamous epithelial cells: 318.3;Suprabasal keratinocytes: 383.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 13.1;eosinophil: 28.7;intermediate monocyte: 22.6;memory B-cell: 13.5;myeloid DC: 14.5;naive B-cell: 11.7;non-classical monocyte: 43.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HaCaT: 1090.1;OE19: 3919.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002139, HPA032047" Supported Supported "Vesicles,Plasma membrane,Cell Junctions" NA NA 64000000 "Cluster 14: Monocytes - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cell Junctions" Vesicles "CAB002139: AB_563468, HPA032047: AB_2674124" "unprognostic (3.96e-3)" "unprognostic (3.40e-1)" "unprognostic (2.32e-1)" "unprognostic (4.71e-3)" "unprognostic (2.49e-2)" "unprognostic (1.12e-1)" "unprognostic (2.02e-1)" "unprognostic (8.11e-3)" "unprognostic (1.41e-2)" "unprognostic (9.85e-3)" "unprognostic (2.29e-3)" "unprognostic (9.60e-2)" "prognostic favorable (2.06e-10)" "unprognostic (2.50e-1)" "unprognostic (9.49e-2)" "unprognostic (9.05e-2)" "unprognostic (1.51e-2)" 46.5 16.0 13.6 23.6 21.6 20.7 68.6 20.8 18.9 243.7 25.8 94.9 88.1 57.0 15.3 952.2 69.9 39.8 145.1 14.6 14.3 120.7 70.9 57.1 15.7 20.7 16.2 46.2 59.6 19.9 37.3 51.5 19.6 68.0 49.0 4.7 226.4 41.8 110.8 932.4 95.7 23.1 14.8 22.7 86.3 12.5 16.2 29.6 86.4 62.2 92.0 68.7 432.6 33.6 268.8 217.8 21.7 18.5 0.2 0.1 330.6 15.3 89.2 5.9 5.2 332.6 289.0 5.4 157.8 9.7 7.5 1090.1 31.6 242.4 1.0 0.6 74.2 11.6 165.1 74.4 34.7 7.3 113.6 0.5 538.6 0.9 43.9 64.2 96.1 7.0 99.6 94.0 0.0 342.6 1.9 96.5 42.3 3919.9 36.2 313.5 0.2 202.5 165.8 674.0 52.2 38.6 33.8 652.1 1.9 98.6 545.9 8.0 152.4 0.3 14.8 6.8 5.1 8.2 31.2 5.5 1.5 12.7 2.6 3.9 13.1 28.7 0.0 22.6 0.0 13.5 0.0 0.2 14.5 11.7 0.2 0.1 0.6 0.8 43.8 4.5 0.1 5.7 13.6 21.6 20.8 18.9 14.6 14.3 20.7 16.2 19.6 14.8 16.2 33.6 56.9 60.9 36.8 4.6 10.6 196.9 218.5 104.5 100.2 1.9 87.3 77.0 87.8 48.6 80.9 132.4 4.2 98.9 1.1 315.9 27.4 212.2 28.5 112.6 21.1 55.2 66.8 3.4 0.5 135.4 167.3 25.6 136.1 247.0 11.4 16.5 41.4 34.1 14.4 0.0 1.6 125.0 81.4 7.7 32.7 8.3 5.0 10.9 12.4 2.8 6.3 18.2 0.0 7.1 13.6 356.2 223.7 0.0 3.9 220.1 141.1 35.6 45.7 4.3 6.6 37.4 18.8 2.5 4.5 318.3 383.3 185.7 6.1 3.2 129.2 301.6 KCNK5 "K2p5.1, TASK-2, TASK2" ENSG00000164626 "Potassium two pore domain channel subfamily K member 5" O95279 6 39188971-39229475 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 35.4;kidney: 37.2" "Cell type enhanced" "Detected in many" "Cholangiocytes: 48.6;Distal enterocytes: 55.6;Gastric mucus-secreting cells: 31.6;Proximal enterocytes: 66.5;Proximal tubular cells: 45.4;Syncytiotrophoblasts: 45.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 34.9;HEL: 36.1;HMC-1: 31.8;K-562: 34.3;OE19: 27.4;T-47d: 25.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA059148 Uncertain Approved Nucleoplasm NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 1: K-562 - Erythropoiesis" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "HPA059148: AB_2683929" "unprognostic (1.46e-1)" "prognostic favorable (3.29e-4)" "unprognostic (1.08e-1)" "unprognostic (2.92e-3)" "unprognostic (8.09e-4)" "unprognostic (3.97e-2)" "unprognostic (2.33e-1)" "unprognostic (9.57e-3)" "unprognostic (7.14e-2)" "unprognostic (3.43e-1)" "prognostic unfavorable (5.85e-4)" "unprognostic (2.98e-1)" "prognostic favorable (4.98e-7)" "unprognostic (2.34e-1)" "unprognostic (7.13e-2)" "unprognostic (1.03e-2)" "prognostic favorable (4.45e-4)" 4.0 3.7 0.1 2.2 0.1 9.6 5.3 0.0 0.1 4.4 0.1 14.2 28.4 2.1 0.2 6.1 2.3 18.8 1.7 0.0 0.2 37.2 23.5 6.1 2.7 0.2 0.2 6.4 20.4 1.9 1.2 8.6 0.1 3.5 8.5 0.1 27.1 2.4 0.2 29.4 35.4 1.3 0.1 2.2 16.7 0.7 0.3 1.8 10.0 0.1 1.9 3.2 6.7 0.0 6.6 5.9 7.7 2.9 0.0 0.0 6.6 0.0 0.0 0.0 0.0 34.9 14.3 0.0 10.2 0.0 0.8 13.2 6.0 0.2 0.0 0.0 4.5 36.1 3.1 0.2 0.0 7.5 31.8 0.0 0.1 0.2 0.0 0.0 0.0 7.8 34.3 0.1 0.0 11.4 16.7 8.1 14.4 27.4 0.0 0.0 1.4 13.6 5.3 5.4 1.9 1.5 5.7 7.3 0.0 2.9 25.9 12.1 0.2 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.0 19.5 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.2 0.2 0.2 0.1 0.1 0.3 0.0 2.3 0.0 19.2 0.0 0.1 3.7 2.5 1.5 5.7 0.0 4.2 3.2 0.6 48.6 7.7 1.8 0.0 28.8 0.8 55.6 5.9 14.5 0.1 2.6 0.3 6.9 0.0 6.1 0.0 11.8 5.3 3.2 31.6 5.3 0.0 2.2 0.0 27.5 2.1 0.0 0.0 15.3 8.2 0.6 3.5 0.7 0.6 0.8 1.8 0.0 0.6 0.0 0.0 0.0 0.0 12.1 25.1 0.0 0.4 2.6 66.5 45.4 1.0 0.0 0.0 2.4 0.6 0.0 1.1 8.2 2.7 45.6 3.5 1.4 11.1 10.4 KCNK7 K2p7.1 ENSG00000173338 "Potassium two pore domain channel subfamily K member 7" Q9Y2U2 11 65592836-65595996 "Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 90.0" "Cell type enriched" "Detected in some" 5 "Suprabasal keratinocytes: 103.7" "Cancer enhanced" "Detected in many" "head and neck cancer: 4.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 15 "basophil: 2.1;naive B-cell: 2.2;neutrophil: 1.5" "Group enriched" "Detected in many" 16 "B-cells: 2.2;granulocytes: 2.1" "Cell line enhanced" "Detected in some" "SCLC-21H: 6.8" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA077577 Approved "Plasma membrane" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 28: Keratinocytes - Keratinization" "Plasma membrane" "HPA077577: AB_2686845" "unprognostic (1.12e-2)" "unprognostic (1.21e-1)" "unprognostic (6.08e-2)" "unprognostic (5.71e-2)" "unprognostic (8.59e-2)" "unprognostic (1.34e-1)" "unprognostic (1.68e-3)" "unprognostic (8.53e-2)" "unprognostic (1.69e-1)" "unprognostic (2.87e-1)" "unprognostic (6.90e-2)" "unprognostic (4.88e-2)" "unprognostic (1.49e-2)" "unprognostic (2.65e-1)" "unprognostic (3.57e-1)" "unprognostic (1.16e-1)" "unprognostic (8.11e-2)" 2.0 0.7 2.7 0.2 2.9 5.4 2.9 3.4 5.7 4.6 1.7 2.1 0.4 1.4 0.1 18.0 2.3 0.3 1.6 2.7 2.4 0.7 0.9 1.7 0.3 2.8 2.8 1.8 0.4 0.0 1.3 0.4 3.0 1.4 0.0 0.7 2.5 0.3 2.6 90.0 1.2 0.2 2.7 2.0 1.2 1.1 2.7 0.4 0.6 0.5 1.0 1.7 9.5 3.4 0.3 1.6 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.3 0.1 0.1 1.0 0.4 0.4 0.1 0.2 2.2 0.0 0.0 0.0 0.5 1.1 0.5 0.9 0.6 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.2 0.0 0.8 0.6 1.3 0.4 1.0 0.5 0.4 0.6 0.6 0.6 0.9 0.0 0.2 0.6 0.1 6.8 1.5 0.3 0.4 0.7 0.0 0.4 1.1 0.0 0.3 1.1 1.0 0.1 0.9 0.7 0.2 0.5 0.6 0.6 2.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 2.2 0.0 0.0 1.5 0.1 0.1 0.0 0.0 0.0 2.7 2.9 3.4 5.7 2.7 2.4 2.8 2.8 3.0 2.7 2.7 3.4 1.1 0.0 0.5 0.3 0.8 19.1 0.4 0.7 0.6 2.1 0.7 1.8 0.2 0.0 0.7 0.0 0.0 0.1 1.6 1.0 0.0 0.1 0.7 0.7 0.3 1.2 1.2 0.0 0.9 0.0 0.1 0.4 0.0 1.7 0.0 0.2 0.7 0.3 0.5 0.0 0.9 0.4 0.0 1.3 4.0 1.8 0.6 0.7 3.6 0.0 0.4 0.1 0.0 1.0 1.8 0.1 4.8 0.0 0.0 0.3 0.3 0.1 1.1 1.1 6.6 0.4 0.8 0.1 1.3 16.3 103.7 0.0 0.6 0.1 0.8 1.3 KCNN4 "hIKCa1, hKCa4, hSK4, IK, KCa3.1" ENSG00000104783 "Potassium calcium-activated channel subfamily N member 4" O15554 19 43766533-43781257 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Immunity, Ion transport, Transport" "Calmodulin-binding, Ion channel" "Disease variant, FDA approved drug targets, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 130.8" "Group enriched" "Detected in many" 6 "Cytotrophoblasts: 231.1;Syncytiotrophoblasts: 763.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 85.7;WM-115: 258.6" "Region enhanced" "Detected in single" "olfactory bulb: 1.9" "Not detected" "Not detected" "HPA013367, HPA053841, HPA059622" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 17: WM-115 - Nervous system development" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane, Cytosol" "HPA013367: , HPA053841: AB_2682278, HPA059622: AB_2684085" "unprognostic (1.23e-2)" "unprognostic (3.22e-2)" "unprognostic (4.29e-1)" "unprognostic (3.74e-3)" "prognostic unfavorable (2.68e-4)" "unprognostic (1.98e-2)" "unprognostic (7.33e-2)" "unprognostic (1.42e-2)" "unprognostic (2.48e-3)" "unprognostic (4.12e-2)" "prognostic unfavorable (4.56e-4)" "unprognostic (9.96e-3)" "prognostic unfavorable (1.05e-14)" "unprognostic (3.70e-2)" "unprognostic (2.17e-2)" "unprognostic (7.50e-2)" "prognostic favorable (1.75e-4)" 3.6 0.7 1.7 11.8 1.9 18.3 12.4 1.3 1.8 11.8 1.4 18.5 6.4 1.6 1.8 6.5 5.8 3.5 1.1 1.5 1.6 1.4 0.8 7.3 12.5 1.6 1.6 0.6 1.0 0.0 0.7 14.3 1.7 28.6 6.2 0.2 130.8 7.5 0.4 29.1 26.0 0.7 1.9 20.5 35.1 2.7 2.0 5.0 2.1 0.2 9.2 18.2 6.5 2.3 22.4 35.2 0.1 0.2 0.0 2.2 55.0 0.8 1.7 0.7 0.1 0.5 85.7 6.7 9.8 0.9 9.1 13.6 0.0 28.8 1.7 40.9 0.0 29.8 48.6 0.5 0.0 0.3 0.3 0.0 2.9 1.3 6.6 52.7 0.0 0.3 2.6 2.3 0.3 18.7 4.8 17.9 0.2 43.1 42.4 16.8 0.7 21.0 13.0 55.3 0.2 0.1 62.2 70.1 32.6 1.7 0.3 15.1 1.5 12.6 75.9 0.4 45.3 0.1 1.4 2.6 45.9 5.1 258.6 5.8 21.1 0.0 0.5 35.3 0.7 37.3 10.4 5.0 30.7 21.6 6.6 6.3 1.1 0.0 20.1 0.9 15.2 11.2 1.7 1.9 1.3 1.8 1.5 1.6 1.6 1.6 1.7 1.9 2.0 2.3 1.6 0.0 1.9 1.3 24.7 2.8 45.7 79.5 3.4 0.2 69.7 56.6 0.4 7.2 18.4 1.8 4.2 231.1 4.1 22.0 0.0 5.9 1.2 1.7 0.2 4.0 0.0 32.4 1.5 3.9 14.1 2.3 57.1 4.2 0.0 0.0 0.4 0.0 43.7 0.0 1.1 8.9 2.0 7.2 78.2 0.3 0.0 23.3 21.4 1.0 2.5 0.1 1.0 0.5 0.8 63.8 22.3 0.0 22.4 63.5 1.0 0.1 2.2 0.5 0.0 0.3 1.4 0.4 1.4 2.1 2.3 763.3 9.5 0.0 51.1 65.6 KCTD4 bA321C24.3 ENSG00000180332 "Potassium channel tetramerization domain containing 4" Q8WVF5 13 45192853-45194717 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 24.6;choroid plexus: 9.4" "Group enriched" "Detected in some" 4 "Inhibitory neurons: 2.6;Oligodendrocyte precursor cells: 10.1;Oligodendrocytes: 9.5" "Group enriched" "Detected in some" 5 "glioma: 1.2;renal cancer: 0.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 20.7;hTERT-RPE1: 12.5;RPTEC TERT1: 11.8;U-138 MG: 13.9;U-87 MG: 27.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040734 Uncertain Approved "Centriolar satellite" NA NA "Cluster 65: Brain - Ion transport" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 68: Oligodendrocytes - Mixed function" "Centriolar satellite" "HPA040734: AB_10963227" "unprognostic (1.36e-1)" "unprognostic (1.02e-1)" "unprognostic (2.08e-1)" "unprognostic (1.19e-2)" "unprognostic (1.70e-1)" "unprognostic (4.68e-2)" "unprognostic (1.74e-1)" "unprognostic (1.66e-3)" "unprognostic (1.63e-1)" "unprognostic (1.73e-1)" "unprognostic (2.15e-1)" "unprognostic (2.98e-2)" 0.1 0.0 20.2 0.0 24.6 0.1 0.5 8.3 17.6 0.1 9.4 1.2 0.2 0.0 0.0 0.0 0.0 0.7 0.2 16.6 11.3 0.2 0.0 0.0 0.0 10.9 10.7 0.0 0.2 0.0 1.8 0.2 9.7 0.0 0.2 0.0 0.5 0.1 0.0 3.1 0.5 0.7 12.4 0.0 0.0 0.0 13.2 0.0 0.0 0.2 0.0 0.0 0.1 13.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.5 0.5 0.0 0.2 0.0 0.0 0.0 0.5 0.6 20.7 0.0 0.0 2.9 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 5.7 12.5 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 13.9 0.0 0.0 3.1 0.0 0.0 0.0 27.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.2 24.6 8.3 17.6 16.6 11.3 10.9 10.7 9.7 12.4 13.2 13.8 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 2.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.8 1.0 0.0 0.0 0.0 10.1 9.5 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 KDF1 "C1orf172, FLJ34633, RP11-344H11.3" ENSG00000175707 "Keratinocyte differentiation factor 1" Q8NAX2 1 26949562-26960468 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Differentiation "Developmental protein" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 32.6;Ductal cells: 29.4;Syncytiotrophoblasts: 29.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 36 "B-cells: 3.4;T-cells: 6.2" "Cell line enhanced" "Detected in some" "A-431: 24.9;BEWO: 20.8;CAPAN-2: 22.7;HaCaT: 21.4;HBEC3-KT: 30.3;hTCEpi: 38.5;OE19: 39.3;SK-BR-3: 25.2" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA028634, HPA028639" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 30: Non-specific - Translation" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 30: Epithelial cell lines - Translation" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane" Cytosol "HPA028634: , HPA028639: AB_10599191" "unprognostic (2.58e-1)" "unprognostic (1.23e-1)" "unprognostic (6.46e-2)" "unprognostic (1.50e-2)" "unprognostic (1.15e-2)" "unprognostic (1.05e-1)" "unprognostic (1.64e-1)" "unprognostic (8.45e-2)" "unprognostic (9.09e-2)" "unprognostic (9.01e-2)" "unprognostic (2.73e-1)" "unprognostic (3.91e-1)" "prognostic favorable (3.04e-13)" "unprognostic (1.38e-3)" "unprognostic (7.83e-2)" "unprognostic (8.03e-2)" "prognostic favorable (4.40e-4)" 0.1 1.1 0.4 1.3 0.3 0.1 10.3 1.6 1.3 4.0 0.3 8.9 12.4 0.9 19.7 20.2 7.4 2.9 0.4 0.4 0.2 11.0 4.7 4.4 0.8 0.3 0.3 0.1 16.2 12.5 10.4 3.9 0.4 7.2 7.1 1.3 12.8 4.6 0.0 17.7 10.5 0.3 0.2 0.6 10.6 2.6 0.3 2.3 10.0 0.0 3.4 4.8 8.3 0.7 24.9 0.0 0.0 0.0 0.0 0.0 20.8 0.0 0.0 0.0 0.0 12.1 22.7 0.0 0.9 0.0 0.0 21.4 0.0 30.3 0.0 0.1 0.4 0.0 0.0 4.4 0.3 0.0 0.0 0.1 38.5 0.0 3.1 0.0 0.0 0.0 1.4 0.0 0.0 14.7 0.0 0.1 1.7 39.3 0.1 0.0 0.0 3.7 5.5 11.7 14.9 0.0 0.2 25.2 0.1 2.7 16.1 0.4 0.2 0.0 0.0 0.0 0.0 2.1 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 3.2 2.5 4.3 3.0 0.1 3.4 6.2 3.8 0.0 0.0 0.0 0.0 0.2 1.7 0.4 0.3 1.6 1.3 0.4 0.2 0.3 0.3 0.4 0.2 0.3 0.7 0.2 12.8 8.8 0.0 0.8 0.0 14.3 0.0 10.8 0.6 15.1 16.3 0.3 12.8 2.5 14.7 0.0 32.6 1.5 17.2 25.4 29.4 0.4 7.3 0.8 0.7 7.8 0.0 0.2 23.2 26.5 0.6 13.7 8.0 0.0 0.1 0.0 4.4 2.7 0.0 0.1 13.1 0.0 0.3 0.0 0.1 0.3 0.1 0.0 0.0 0.2 1.1 0.0 0.0 0.1 21.8 25.2 0.0 0.4 16.8 26.2 10.1 5.1 2.5 0.0 0.0 0.3 6.3 7.5 14.4 0.0 29.7 1.2 0.0 16.9 19.0 KIF14 KIAA0042 ENSG00000118193 "Kinesin family member 14" Q15058 1 200551497-200620751 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Motor protein" "Ciliopathy, Disease variant, Meckel syndrome, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.5;lymphoid tissue: 10.9" "Cell type enhanced" "Detected in many" "Erythroid cells: 27.1;Granulosa cells: 13.2;Spermatocytes: 22.8;Spermatogonia: 16.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA038061, HPA058220" Uncertain Supported "Midbody ring,Cytosol" Yes Yes "Cluster 18: Basophils - Vesicular transport" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "Midbody ring" "HPA038061: AB_10669515, HPA058220: AB_2683642" "unprognostic (1.84e-1)" "unprognostic (7.15e-2)" "unprognostic (2.00e-2)" "unprognostic (1.87e-2)" "unprognostic (2.74e-1)" "unprognostic (1.51e-1)" "unprognostic (1.18e-3)" "prognostic unfavorable (8.64e-4)" "unprognostic (8.47e-3)" "unprognostic (1.02e-1)" "unprognostic (2.54e-5)" "unprognostic (2.31e-2)" "unprognostic (0.00e+0)" "unprognostic (6.28e-3)" "unprognostic (3.31e-1)" "unprognostic (8.14e-2)" "unprognostic (7.44e-2)" 0.2 0.2 0.1 2.0 0.0 6.5 0.3 0.2 0.3 0.2 0.1 0.9 1.2 0.3 0.0 1.0 0.0 0.2 0.0 0.1 0.1 0.0 0.3 0.2 3.2 0.1 0.2 0.0 0.0 0.0 0.0 0.9 0.1 0.0 1.2 0.1 0.1 0.0 0.0 1.0 1.1 0.6 0.0 0.6 0.6 2.5 0.1 10.9 0.1 0.0 3.2 0.4 0.3 0.1 29.7 17.3 26.8 15.0 0.8 3.0 14.8 20.0 11.7 18.7 16.8 10.5 15.1 18.0 7.0 9.6 11.6 23.0 21.6 13.3 26.7 22.1 11.3 28.8 24.8 10.3 0.1 45.5 15.7 0.6 0.6 20.9 17.8 4.0 13.5 26.3 44.0 22.6 23.5 12.1 26.9 14.2 22.6 8.7 15.0 24.3 35.4 22.8 6.3 8.3 12.7 14.0 28.3 9.5 11.0 19.8 12.9 11.6 11.1 14.7 17.3 16.2 35.3 8.2 8.9 25.8 8.6 24.0 30.5 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.2 0.3 0.1 0.1 0.1 0.2 0.1 0.0 0.1 0.1 1.0 0.0 0.0 0.0 1.9 2.4 1.0 1.1 0.6 2.3 1.5 1.9 0.8 0.0 0.9 0.0 2.1 4.2 0.6 2.5 0.0 0.2 4.1 3.7 2.2 1.6 0.0 27.1 1.1 0.0 7.7 3.3 10.2 5.0 2.5 13.2 2.5 0.9 5.4 0.0 0.9 5.2 0.0 2.9 1.9 2.5 0.6 2.3 0.0 0.0 0.4 0.5 0.0 0.5 0.8 0.3 0.0 0.7 11.3 1.2 0.2 0.1 1.4 0.8 6.6 1.4 2.1 22.8 16.3 8.3 0.9 1.4 2.3 0.7 4.3 1.9 KIF15 "HKLP2, KNSL7, NY-BR-62" ENSG00000163808 "Kinesin family member 15" Q9NS87 3 44761721-44873376 "Plasma proteins, Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 5.0;lymphoid tissue: 9.2;testis: 7.3" "Group enriched" "Detected in many" 4 "Early spermatids: 177.5;Late spermatids: 78.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA035516, HPA035517, HPA061469" Approved NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA035516: AB_2674664, HPA035517: AB_10671935, HPA061469: " "unprognostic (2.26e-1)" "unprognostic (1.85e-1)" "prognostic favorable (3.12e-4)" "unprognostic (3.49e-2)" "unprognostic (2.69e-1)" "unprognostic (5.17e-3)" "unprognostic (6.68e-7)" "unprognostic (1.35e-2)" "unprognostic (1.51e-2)" "unprognostic (6.94e-2)" "unprognostic (3.14e-4)" "unprognostic (2.72e-2)" "unprognostic (0.00e+0)" "unprognostic (1.38e-2)" "unprognostic (1.83e-1)" "unprognostic (6.13e-2)" "unprognostic (3.58e-1)" 0.2 0.1 0.1 1.2 0.1 5.0 0.4 0.2 0.2 0.3 0.0 1.4 1.4 0.3 0.0 1.1 0.1 0.2 0.0 0.1 0.1 0.0 0.1 0.2 2.2 0.1 0.1 0.1 0.0 0.0 0.0 0.7 0.1 0.2 1.6 0.1 0.2 0.1 0.0 0.8 1.4 0.4 0.1 0.4 0.8 7.3 0.1 9.2 0.0 0.0 2.2 0.3 0.4 0.1 7.5 3.9 17.6 12.8 1.2 1.4 3.9 8.6 5.3 10.8 9.0 6.6 7.2 13.8 2.8 3.1 4.0 6.3 10.1 4.7 13.1 11.6 2.3 14.9 7.7 8.4 0.1 15.6 6.6 0.3 0.2 7.3 7.1 1.6 8.6 18.4 9.3 17.2 8.2 3.9 30.0 5.7 18.2 9.7 7.0 11.9 19.0 7.9 2.4 4.9 8.2 7.8 14.2 4.6 2.9 4.6 7.7 11.7 4.8 10.4 8.5 8.8 11.5 7.2 12.7 17.3 5.5 16.3 10.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.2 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 2.6 1.6 1.9 0.4 0.9 0.0 0.1 0.5 0.8 1.8 0.0 0.7 0.0 2.1 3.3 0.8 2.5 0.0 0.8 177.5 1.3 1.7 1.2 0.0 28.0 3.2 0.0 5.9 1.9 5.1 1.4 0.0 12.3 0.0 0.2 3.5 0.0 3.8 2.6 0.0 1.6 1.4 78.0 0.0 1.8 0.0 0.0 0.3 0.7 1.0 3.0 4.7 0.5 0.1 0.4 9.7 0.5 0.5 0.1 0.2 0.0 0.0 0.4 1.9 20.2 14.7 6.0 1.0 0.7 3.1 1.1 5.3 0.5 KIF18A "DKFZP434G2226, PPP1R99" ENSG00000121621 "Kinesin family member 18A" Q8NI77 11 28020619-28108156 "Predicted intracellular proteins" "Protein transport, Transport" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 8.2;lymphoid tissue: 9.6;testis: 13.7" "Cell type enhanced" "Detected in many" "Early spermatids: 43.1;Spermatocytes: 78.7;Spermatogonia: 28.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "basophil: 4.1;memory B-cell: 1.0;NK-cell: 1.4;T-reg: 1.1" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA039312, HPA039484" Approved Supported "Microtubules,Cytokinetic bridge" Yes Yes "Cluster 41: Basophils - Cellular respiration" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Microtubules, Cytokinetic bridge" "HPA039312: AB_10794087, HPA039484: AB_10795252" "unprognostic (3.79e-1)" "unprognostic (2.63e-1)" "unprognostic (7.09e-3)" "unprognostic (3.80e-2)" "unprognostic (6.56e-2)" "unprognostic (1.39e-1)" "unprognostic (1.34e-7)" "unprognostic (2.43e-3)" "unprognostic (2.04e-3)" "unprognostic (1.23e-2)" "unprognostic (1.72e-4)" "unprognostic (4.41e-2)" "unprognostic (0.00e+0)" "unprognostic (7.88e-3)" "unprognostic (1.67e-1)" "unprognostic (1.43e-1)" "unprognostic (2.50e-1)" 0.2 0.1 0.0 1.9 0.1 8.2 0.7 0.0 0.1 0.7 0.1 1.6 1.5 0.5 0.3 1.4 0.3 0.5 0.0 0.1 0.1 0.3 0.3 1.0 4.7 0.1 0.1 0.1 0.1 0.1 0.1 1.5 0.1 0.3 2.0 0.6 0.3 0.4 0.2 1.2 1.4 0.8 0.1 0.7 0.6 13.7 0.2 9.6 1.1 0.1 4.6 0.7 0.5 0.1 27.9 27.4 27.2 19.0 0.9 3.7 9.1 28.3 13.2 44.2 46.0 9.2 11.0 23.3 10.0 14.7 24.1 27.2 23.4 11.1 61.4 23.4 14.2 15.2 17.8 11.8 2.1 22.6 13.4 6.8 1.4 15.5 18.1 7.8 17.2 19.0 24.6 20.0 25.2 14.8 23.1 16.7 13.4 18.0 11.1 17.8 65.0 11.6 12.5 8.0 16.3 12.6 23.7 11.1 7.8 16.5 23.8 6.9 10.1 35.0 27.2 33.2 37.4 7.9 19.8 23.4 21.0 16.5 25.2 4.1 0.0 0.3 0.1 0.2 0.3 1.0 0.4 0.2 0.3 0.4 0.3 0.1 0.0 1.4 0.0 0.3 1.1 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 1.2 3.2 0.0 0.0 4.7 2.3 1.3 1.4 1.2 0.3 1.3 2.9 0.5 0.0 2.2 0.0 6.2 4.6 2.8 1.9 0.0 0.6 43.1 3.4 2.5 1.1 1.8 15.4 0.2 0.9 7.1 5.4 1.5 3.4 4.5 9.7 1.4 0.0 2.2 0.0 0.1 1.9 0.0 1.6 1.4 8.7 0.6 1.4 0.0 1.0 1.1 0.7 1.0 0.5 0.9 0.5 0.1 0.4 5.1 0.2 0.2 0.6 1.7 1.9 0.0 2.5 1.9 78.7 28.3 4.3 1.0 1.6 3.9 2.7 3.6 0.5 KIF18B ENSG00000186185 "Kinesin family member 18B" Q86Y91 17 44924709-44947773 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 12.7;lymphoid tissue: 14.4" "Cell type enhanced" "Detected in some" "Erythroid cells: 9.0;Extravillous trophoblasts: 3.8;Granulosa cells: 5.9;Oligodendrocyte precursor cells: 7.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Region enhanced" "Detected in single" "white matter: 1.4" "Low region specificity" "Detected in many" HPA024205 Enhanced Supported "Nucleoplasm,Nuclear bodies,Microtubule ends,Cytosol" Yes Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Microtubule ends" "Nuclear bodies, Cytosol" "HPA024205: AB_1852472" "unprognostic (1.88e-1)" "unprognostic (9.92e-2)" "unprognostic (4.61e-2)" "unprognostic (1.13e-2)" "unprognostic (4.17e-1)" "unprognostic (7.27e-3)" "prognostic unfavorable (2.44e-6)" "unprognostic (3.34e-3)" "prognostic unfavorable (6.90e-4)" "unprognostic (1.98e-1)" "prognostic unfavorable (2.16e-4)" "unprognostic (8.18e-2)" "unprognostic (0.00e+0)" "unprognostic (4.69e-3)" "unprognostic (1.93e-1)" "unprognostic (3.08e-1)" "unprognostic (1.68e-2)" 0.4 0.4 0.3 3.8 0.4 12.7 0.2 0.7 0.3 0.9 0.3 2.0 2.7 0.4 0.0 5.1 0.2 0.4 0.3 0.3 0.4 0.2 0.4 0.8 5.7 0.5 1.1 0.1 0.1 0.0 0.1 1.9 0.6 0.2 1.7 0.1 0.7 0.0 0.4 3.0 2.5 1.1 0.3 2.9 1.5 2.9 0.6 14.4 0.2 0.0 4.7 0.6 1.6 0.5 31.5 41.7 35.3 32.8 0.8 3.0 28.1 25.8 10.3 34.6 26.9 34.0 27.4 28.3 10.9 10.8 21.5 34.0 25.1 11.3 17.9 56.6 36.4 35.4 51.7 22.1 0.0 30.0 30.2 0.7 0.6 29.7 12.2 4.7 17.9 29.2 28.1 48.0 18.2 25.9 60.0 31.1 25.4 30.4 28.9 43.5 51.8 19.2 5.8 16.7 26.2 24.7 18.0 16.1 9.8 17.0 30.2 21.6 11.2 49.9 48.0 28.8 56.8 15.1 15.7 34.4 16.3 22.9 33.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.1 0.1 0.0 0.3 0.4 0.7 0.3 0.3 0.4 0.5 1.1 0.6 0.3 0.6 0.5 0.1 0.0 0.0 0.0 0.9 0.4 0.1 0.2 0.0 0.5 0.5 0.4 2.6 0.0 0.0 0.0 0.0 2.4 0.4 1.9 0.0 0.0 0.0 0.3 0.8 0.6 0.0 9.0 0.3 0.0 3.8 1.4 1.5 0.5 0.0 5.9 0.4 0.3 2.3 0.0 0.3 1.6 0.0 2.2 1.1 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.0 7.1 0.1 0.1 0.0 0.0 2.1 0.2 0.3 0.0 0.0 0.3 0.0 0.2 0.8 1.1 2.9 2.5 0.4 0.8 1.3 0.3 3.2 0.3 KIF20A RAB6KIFL ENSG00000112984 "Kinesin family member 20A" O95235 5 138178719-138187723 "Predicted intracellular proteins" "Protein transport, Transport" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 14.1;lymphoid tissue: 24.6;testis: 11.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 11.0;Erythroid cells: 24.6;Extravillous trophoblasts: 13.1;Granulosa cells: 11.1;Spermatocytes: 21.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "NK-cell: 6.6;T-reg: 2.5" "Group enriched" "Detected in many" 46 "NK-cells: 6.6;T-cells: 2.5" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA036909, HPA036910" Approved Uncertain "Nucleoplasm,Cytokinetic bridge" Yes Yes "Cluster 15: NK-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cytokinetic bridge" "HPA036909: AB_10670245, HPA036910: AB_10671716" "unprognostic (7.50e-2)" "unprognostic (2.43e-1)" "unprognostic (1.39e-3)" "unprognostic (1.21e-2)" "unprognostic (3.47e-2)" "unprognostic (2.60e-2)" "prognostic unfavorable (2.14e-12)" "prognostic unfavorable (6.79e-4)" "unprognostic (2.86e-2)" "unprognostic (3.16e-1)" "prognostic unfavorable (1.90e-4)" "unprognostic (9.73e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (9.05e-2)" "unprognostic (2.61e-1)" "unprognostic (1.09e-1)" "unprognostic (3.16e-1)" 0.7 0.8 0.0 4.5 0.1 14.1 1.3 0.1 0.1 1.0 0.1 3.3 3.5 1.4 0.0 6.6 0.4 0.8 0.5 0.0 0.1 0.4 0.9 0.9 8.6 0.1 0.2 0.2 0.2 0.1 0.0 5.4 0.1 0.2 5.1 0.0 1.0 0.1 0.1 4.4 2.8 5.8 0.0 1.9 2.1 11.7 0.5 24.6 0.5 0.1 13.1 1.6 2.0 0.1 87.8 59.5 127.8 84.4 6.7 12.3 53.9 75.0 68.9 162.3 121.4 111.9 80.5 38.8 39.2 96.5 60.6 85.9 121.7 142.5 160.9 56.4 57.4 57.2 101.1 70.7 0.3 28.2 25.1 4.8 2.3 86.2 49.5 27.1 106.7 53.9 24.4 70.4 113.9 81.5 47.6 26.7 80.6 51.8 63.7 51.2 128.5 39.5 43.9 42.3 37.8 37.5 144.1 47.9 30.9 161.6 60.8 28.5 51.1 41.6 60.5 38.0 126.4 36.0 37.5 42.0 26.7 81.1 82.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 2.5 0.3 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.1 0.0 0.5 0.1 0.3 0.0 1.7 0.0 0.8 0.4 0.4 2.9 0.0 0.0 1.1 1.3 0.3 0.0 0.7 0.0 0.0 11.0 0.1 2.8 0.0 0.1 1.0 1.0 1.9 1.7 0.0 24.6 0.0 0.0 13.1 3.1 2.6 1.3 4.5 11.1 3.3 0.4 6.1 0.0 0.0 1.6 6.1 2.2 0.4 2.0 0.3 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.4 3.0 0.3 1.2 0.0 0.9 0.0 0.0 0.5 4.4 21.7 7.5 5.3 0.4 1.0 0.7 0.8 3.4 0.6 KIF23 "KNSL5, MKLP-1, MKLP1" ENSG00000137807 "Kinesin family member 23" Q02241 15 69414246-69448427 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 21.6;lymphoid tissue: 15.9" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 24.2;Erythroid cells: 42.3;Extravillous trophoblasts: 32.4;Granulosa cells: 22.4;Spermatocytes: 70.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "eosinophil: 4.6" "Group enriched" "Detected in many" 13 "granulocytes: 4.6;monocytes: 1.2;T-cells: 1.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB010414, HPA045208, HPA068831" Uncertain Enhanced "Nucleoplasm,Midbody ring,Mitotic spindle" Yes Yes "Cluster 49: Eosinophils - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Midbody ring, Mitotic spindle" "CAB010414: AB_631959, HPA045208: AB_2679254, HPA068831: AB_2686045" "unprognostic (1.29e-1)" "unprognostic (2.40e-1)" "unprognostic (5.57e-2)" "prognostic unfavorable (8.62e-4)" "unprognostic (1.86e-1)" "unprognostic (7.99e-3)" "prognostic unfavorable (3.18e-5)" "unprognostic (1.43e-3)" "unprognostic (4.25e-3)" "unprognostic (2.60e-1)" "prognostic unfavorable (3.69e-5)" "unprognostic (5.85e-3)" "unprognostic (0.00e+0)" "unprognostic (1.15e-2)" "unprognostic (2.59e-1)" "unprognostic (1.17e-1)" "unprognostic (9.17e-2)" 1.0 1.5 0.3 5.7 0.2 21.6 1.4 0.2 0.3 1.5 1.4 4.1 3.9 2.0 0.1 5.3 0.9 1.3 0.6 0.3 0.2 4.6 0.5 1.5 7.9 0.2 0.3 0.7 0.5 0.4 0.1 6.4 0.3 0.9 5.0 0.2 1.1 1.2 0.1 3.7 3.8 4.2 0.2 2.2 2.0 10.6 0.3 15.9 0.3 0.2 9.8 1.8 2.1 0.2 100.7 81.5 64.2 59.0 3.7 7.3 36.3 105.3 57.0 154.8 120.6 50.2 72.4 56.8 31.4 53.1 78.6 110.5 121.6 39.5 158.7 52.9 60.2 55.3 78.8 30.7 2.1 55.6 48.3 3.3 4.2 71.8 60.5 19.4 52.0 46.9 36.0 70.2 95.4 44.1 31.2 28.2 71.6 35.5 33.2 37.0 133.8 31.2 39.3 49.7 32.5 25.3 120.4 51.9 44.9 74.5 50.6 25.3 34.5 90.0 120.8 62.0 157.6 26.3 74.3 48.4 31.5 72.2 78.0 0.0 1.2 4.6 0.0 0.5 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.6 0.0 1.2 0.3 0.3 0.2 0.2 0.3 0.3 0.2 0.2 0.3 0.3 0.2 0.3 0.2 0.4 0.0 0.5 0.0 2.3 1.9 3.7 4.2 0.0 0.2 1.8 2.8 0.8 5.7 4.7 7.3 2.1 24.2 1.4 3.3 3.9 1.8 13.3 13.1 3.6 2.2 1.8 42.3 1.8 0.0 32.4 5.8 3.6 8.7 2.5 22.4 3.9 0.3 8.1 0.0 1.0 3.1 0.0 2.8 3.4 4.8 0.9 3.2 0.0 1.0 8.1 0.2 0.0 0.0 0.2 0.4 0.4 1.9 6.8 1.6 0.8 0.9 3.6 0.1 6.6 0.4 8.2 70.8 20.9 11.3 1.0 2.5 4.2 3.6 8.6 3.3 KIF2C "CT139, KNSL6, MCAK" ENSG00000142945 "Kinesin family member 2C" Q99661 1 44739818-44767767 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 33.0;lymphoid tissue: 37.4;testis: 76.5" "Cell type enriched" "Detected in many" 4 "Late spermatids: 1860.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "T-reg: 2.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Region enhanced" "Detected in some" "white matter: 2.1" "Not detected" "Not detected" "HPA006219, HPA079172" Enhanced Supported Nucleoplasm,Midbody,Centrosome Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Centrosome" Midbody "HPA006219: AB_2667540, HPA079172: " "unprognostic (3.29e-2)" "unprognostic (1.35e-2)" "unprognostic (1.03e-2)" "unprognostic (1.71e-3)" "unprognostic (2.77e-1)" "unprognostic (5.17e-2)" "prognostic unfavorable (3.07e-7)" "unprognostic (7.49e-3)" "unprognostic (3.33e-3)" "unprognostic (3.66e-1)" "prognostic unfavorable (6.86e-4)" "unprognostic (4.27e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.33e-3)" "unprognostic (1.49e-1)" "unprognostic (1.86e-2)" "unprognostic (2.41e-1)" 0.7 0.8 0.7 7.0 0.7 33.0 1.6 2.3 0.7 1.8 1.1 6.2 5.5 1.8 0.7 7.3 0.9 1.3 1.3 0.6 1.1 0.8 0.7 1.3 16.4 1.1 0.9 0.6 0.5 1.3 0.4 5.4 1.4 0.8 7.6 0.8 1.3 0.7 0.9 6.0 5.1 3.2 0.9 3.7 3.5 76.5 0.8 37.4 1.1 0.7 19.2 2.1 2.7 0.8 119.7 45.8 99.6 79.8 5.3 11.6 66.6 86.9 62.1 175.0 151.3 77.6 84.2 136.2 41.3 43.2 121.7 55.2 102.8 59.6 158.2 89.1 44.4 162.1 83.3 65.5 0.6 121.5 71.8 2.7 5.8 125.0 60.3 16.5 57.6 95.4 130.4 113.1 112.4 46.5 127.5 72.9 97.1 58.4 56.5 101.1 149.3 86.4 29.6 42.8 68.3 48.5 116.1 81.6 71.5 71.9 47.2 90.7 34.7 62.9 124.2 69.0 155.6 59.4 65.0 195.3 40.3 115.4 123.9 0.0 0.0 0.0 0.9 0.0 0.0 0.6 1.7 1.2 0.1 0.1 0.3 0.2 0.0 2.0 0.1 0.8 2.9 0.5 0.7 0.7 2.3 0.7 0.6 1.1 1.1 0.9 1.4 0.9 0.8 0.8 0.1 0.0 0.5 1.6 1.3 1.8 0.5 2.4 0.0 1.0 0.9 0.9 1.6 0.0 1.7 1.8 2.1 12.2 1.9 2.9 1.9 0.3 461.1 1.2 1.4 1.6 0.0 34.5 0.8 0.4 23.4 3.2 3.1 2.1 0.0 13.0 2.9 0.2 9.2 0.0 1.0 3.5 0.0 1.9 1.5 1860.6 9.3 3.4 0.0 1.0 4.3 0.4 0.0 0.5 0.2 0.1 0.2 6.8 7.8 0.8 0.3 0.2 0.3 0.2 6.6 0.8 3.4 60.6 36.8 4.6 0.4 3.7 2.7 0.8 7.4 0.7 KIF4A "FLJ12530, FLJ12655, FLJ14204, FLJ20631, HSA271784, KIF4, KIF4-G1, MRX100" ENSG00000090889 "Kinesin family member 4A" O95239 X 70290104-70420886 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA-binding, Motor protein" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 11.2;lymphoid tissue: 12.6" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 18.6;Erythroid cells: 29.5;Extravillous trophoblasts: 11.5;Granulosa cells: 12.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA034745, HPA034746, HPA061583" Approved Supported Nucleoplasm,Midbody Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Midbody" "HPA034745: AB_10670978, HPA034746: AB_10670173, HPA061583: AB_2684564" "unprognostic (8.17e-3)" "unprognostic (2.78e-2)" "unprognostic (1.02e-2)" "unprognostic (3.46e-3)" "unprognostic (3.20e-1)" "unprognostic (1.64e-1)" "prognostic unfavorable (7.37e-6)" "unprognostic (2.18e-3)" "unprognostic (5.06e-3)" "unprognostic (1.34e-1)" "prognostic unfavorable (9.44e-6)" "unprognostic (3.79e-2)" "unprognostic (0.00e+0)" "unprognostic (3.09e-2)" "unprognostic (1.10e-1)" "unprognostic (1.09e-1)" "unprognostic (1.47e-1)" 0.3 0.3 0.3 3.2 0.2 11.2 0.7 0.1 0.3 0.6 0.3 3.7 3.1 0.8 0.0 3.6 1.5 0.5 0.2 0.2 0.5 0.2 0.5 0.5 5.5 0.9 0.7 0.1 0.1 0.1 0.5 2.3 0.6 0.1 4.5 0.6 0.5 0.1 0.1 2.2 3.3 1.3 0.7 2.4 1.7 1.5 0.6 12.6 0.2 0.0 6.6 0.9 1.1 0.2 60.2 41.1 61.0 30.1 2.9 5.1 24.0 44.7 23.8 59.7 51.6 46.7 34.3 36.7 27.4 22.1 46.2 35.1 66.6 24.2 66.8 42.5 33.4 41.7 50.1 33.4 0.7 46.7 27.8 1.7 1.5 49.6 28.2 7.3 37.0 27.7 53.8 79.1 57.0 38.7 43.0 23.1 61.7 63.8 43.2 47.1 82.2 34.6 14.5 23.4 40.1 33.5 72.9 30.5 18.6 30.6 24.5 18.1 26.0 39.3 50.6 42.6 54.1 22.6 41.7 52.0 20.8 50.4 60.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.3 0.2 0.1 0.3 0.2 0.5 0.9 0.7 0.6 0.7 0.6 0.2 0.1 0.0 0.5 1.3 1.3 1.8 0.3 1.4 0.6 0.2 1.1 0.8 0.4 1.5 0.2 0.0 0.0 7.0 0.9 2.2 0.0 0.0 0.4 18.6 1.5 1.3 1.2 29.5 1.9 0.0 11.5 2.1 3.1 1.6 0.0 12.2 1.1 0.1 5.3 0.0 1.9 4.6 2.0 1.3 0.7 0.8 0.0 1.4 0.0 0.0 0.2 3.1 0.0 2.0 0.7 0.1 0.1 0.0 8.2 0.4 0.3 0.1 0.4 0.0 0.0 0.2 2.9 8.7 5.4 7.2 0.3 1.8 1.8 1.3 6.6 0.5 KIFC1 "HSET, KNSL2" ENSG00000237649 "Kinesin family member C1" Q9BW19 6 33391823-33409896 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 39.7;lymphoid tissue: 47.5" "Cell type enhanced" "Detected in many" "Early spermatids: 32.0;Erythroid cells: 62.3;Extravillous trophoblasts: 39.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "T-reg: 1.6" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA055997, HPA062674" Enhanced Approved Centrosome NA Yes "Cluster 40: NK-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Centrosome "HPA055997: AB_2683001, HPA062674: AB_2684829" "unprognostic (7.33e-2)" "unprognostic (1.28e-2)" "unprognostic (2.17e-1)" "unprognostic (2.65e-2)" "unprognostic (1.41e-1)" "unprognostic (2.30e-2)" "prognostic unfavorable (7.07e-8)" "unprognostic (6.34e-3)" "unprognostic (9.36e-3)" "unprognostic (8.58e-2)" "prognostic unfavorable (4.21e-4)" "unprognostic (1.83e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (5.17e-2)" "unprognostic (6.66e-2)" "unprognostic (1.48e-1)" "unprognostic (4.52e-1)" 1.1 1.1 0.2 10.6 0.3 39.7 2.2 0.3 1.2 2.5 0.4 8.0 8.8 1.8 0.2 11.7 0.8 1.5 0.6 0.7 0.3 0.8 1.0 2.3 24.6 0.4 0.7 2.0 0.7 0.3 0.6 5.5 0.5 0.9 8.2 0.4 2.1 0.2 0.2 9.8 8.1 4.1 0.2 5.3 4.7 12.3 0.6 47.5 0.7 0.4 24.9 2.7 3.9 0.5 133.5 47.9 120.6 124.2 5.2 8.1 64.0 82.5 48.4 122.6 104.6 80.6 53.3 120.2 38.3 41.5 102.0 88.1 87.1 60.7 79.7 114.3 60.3 93.9 71.6 73.5 0.5 96.0 75.7 2.5 4.7 73.2 38.8 13.8 64.2 87.5 76.0 112.3 81.0 86.2 125.7 103.2 47.5 67.6 48.4 129.7 110.7 61.4 38.4 42.8 100.1 57.2 54.3 91.9 44.1 51.3 78.7 105.4 32.2 74.6 104.6 56.2 128.9 58.2 132.4 126.1 18.8 94.8 101.0 0.4 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.6 0.2 0.2 0.0 0.0 0.0 1.0 0.3 0.0 1.6 0.5 0.2 0.3 0.3 1.2 0.7 0.3 0.4 0.7 0.5 0.2 0.6 0.5 0.4 0.0 2.5 1.0 4.1 5.6 1.5 4.6 2.2 0.4 2.8 2.2 0.5 0.0 1.9 0.0 0.0 18.7 3.7 8.8 0.0 0.7 32.0 2.7 1.9 2.4 0.0 62.3 0.3 0.0 39.6 4.2 4.1 6.1 1.3 15.0 1.8 0.3 14.3 0.0 0.3 8.0 2.0 2.4 9.8 12.0 0.3 4.7 3.6 1.0 3.1 0.3 0.0 1.0 0.6 0.3 2.1 0.7 12.0 0.9 2.1 0.7 0.8 0.5 0.0 2.5 7.5 13.9 9.6 14.4 3.7 6.7 5.7 0.6 12.1 3.1 KLC3 "KLC2L, KLCt, KNS2B" ENSG00000104892 "Kinesin light chain 3" Q6P597 19 45333434-45351520 "Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 26.1;skin 1: 104.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 142.0;Basal prostatic cells: 50.8;Ductal cells: 39.1;Prostatic glandular cells: 66.9;Suprabasal keratinocytes: 183.3" "Cancer enhanced" "Detected in many" "head and neck cancer: 8.3" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 36.1;HaCaT: 16.2;HBEC3-KT: 10.5;hTCEpi: 12.9" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA052797, HPA056508" Approved Approved "Nucleoplasm,Actin filaments,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "Actin filaments" "Nucleoplasm, Cytosol" "HPA052797: AB_2681954, HPA056508: AB_2683159" "unprognostic (4.11e-2)" "unprognostic (3.71e-1)" "unprognostic (3.07e-4)" "prognostic unfavorable (1.46e-4)" "unprognostic (3.47e-3)" "unprognostic (1.13e-1)" "unprognostic (4.42e-2)" "unprognostic (2.29e-1)" "unprognostic (2.53e-1)" "unprognostic (1.75e-2)" "unprognostic (1.49e-1)" "unprognostic (2.74e-2)" "unprognostic (4.79e-3)" "unprognostic (1.94e-1)" "unprognostic (3.55e-3)" "unprognostic (4.14e-1)" "unprognostic (2.37e-1)" 0.3 0.2 0.5 0.3 1.1 3.0 3.3 1.3 0.8 10.0 0.0 0.1 0.1 0.2 2.1 26.1 0.3 0.2 0.2 0.4 0.2 5.9 0.2 0.9 0.3 0.5 0.0 0.2 4.0 4.0 2.7 0.2 0.2 2.6 0.2 1.0 11.6 1.0 0.9 104.1 0.3 0.0 0.0 0.3 0.5 3.7 0.2 1.0 0.7 0.0 1.8 0.2 20.5 0.7 36.1 0.2 0.2 0.4 0.1 0.1 2.8 0.2 0.0 0.0 0.1 3.5 6.5 0.3 2.8 0.0 3.7 16.2 2.2 10.5 0.2 0.8 5.3 0.1 1.1 0.7 0.0 0.3 2.2 0.0 12.9 0.1 2.5 0.4 0.0 0.5 0.6 0.4 0.1 4.7 0.1 0.4 0.8 0.6 1.1 5.6 0.0 0.3 0.3 1.3 4.5 0.7 0.3 7.3 1.0 0.4 6.5 0.1 0.0 0.4 3.6 0.3 0.4 0.7 0.8 0.3 0.2 0.2 0.4 0.9 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.0 0.2 0.2 0.2 0.4 0.2 0.2 0.2 0.1 0.0 0.5 1.1 1.3 0.8 0.4 0.2 0.5 0.0 0.2 0.0 0.2 0.7 0.2 0.0 2.4 0.3 0.0 142.0 50.8 17.5 14.8 0.8 10.3 25.3 0.4 2.8 7.3 1.8 0.0 0.2 0.2 0.2 9.8 39.1 3.0 0.9 0.3 1.7 0.0 2.7 0.3 3.1 0.7 1.4 0.0 2.4 0.0 6.7 0.4 0.0 0.3 1.7 0.4 0.5 6.1 0.0 10.9 12.0 1.8 0.4 14.2 0.0 0.8 0.7 0.0 0.0 0.0 11.8 0.0 0.4 0.0 66.9 0.0 1.4 3.8 2.0 0.0 1.1 2.5 0.6 11.3 25.6 183.3 0.7 1.0 0.0 0.1 22.0 KLF5 "BTEB2, CKLF, IKLF" ENSG00000102554 "Kruppel like factor 5" Q13887 13 73054976-73077541 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 242.0;skin 1: 234.9" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 1105.5;Basal squamous epithelial cells: 757.5;Glandular and luminal cells: 678.2;Squamous epithelial cells: 1028.4;Suprabasal keratinocytes: 685.9;Urothelial cells: 1495.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 21 "basophil: 24.0" "Lineage enriched" "Detected in single" 140 "granulocytes: 24.0" "Cell line enhanced" "Detected in many" "CAPAN-2: 111.8;HaCaT: 128.8;HBEC3-KT: 112.2;hTCEpi: 156.1;OE19: 246.3;RT4: 136.3;SiHa: 114.5" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 23.2" HPA040398 Approved Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "Golgi apparatus, Vesicles" "HPA040398: AB_10673267" "unprognostic (7.90e-3)" "unprognostic (5.11e-2)" "unprognostic (2.03e-2)" "unprognostic (1.56e-1)" "unprognostic (4.69e-2)" "unprognostic (2.75e-1)" "unprognostic (1.18e-1)" "unprognostic (3.97e-2)" "unprognostic (5.82e-1)" "unprognostic (1.47e-2)" "prognostic unfavorable (2.55e-4)" "unprognostic (4.43e-2)" "unprognostic (1.42e-3)" "unprognostic (3.56e-3)" "unprognostic (3.98e-1)" "unprognostic (5.09e-2)" "unprognostic (1.54e-2)" 6.5 5.9 4.2 18.0 9.1 63.5 36.2 0.6 3.3 49.9 2.7 161.2 130.4 6.7 6.6 242.0 37.5 55.9 3.3 2.6 3.4 8.5 4.7 29.6 2.0 0.8 3.4 4.5 11.9 0.5 10.9 18.8 0.7 23.1 145.4 0.4 79.8 14.4 19.2 234.9 146.2 6.6 0.5 1.5 82.2 12.0 4.1 12.0 25.7 7.8 53.6 111.5 122.2 1.0 22.3 31.1 0.2 0.4 1.1 1.5 34.1 12.9 29.8 5.6 6.9 28.5 111.8 0.4 68.9 11.4 2.3 128.8 39.0 112.2 8.9 0.9 11.0 0.4 61.9 2.8 7.8 10.5 1.9 8.1 156.1 1.7 61.1 5.7 0.1 3.8 1.6 2.2 25.5 7.9 2.1 0.8 1.4 246.3 43.3 2.0 28.3 2.5 87.3 136.3 2.9 1.3 114.5 18.3 8.5 13.9 2.5 2.5 0.3 7.8 23.1 0.2 5.4 3.7 1.9 3.8 10.8 2.1 9.5 24.0 0.0 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.1 0.1 4.2 9.1 0.6 3.3 2.6 3.4 0.8 3.4 0.7 0.5 4.1 1.0 7.8 163.5 123.3 0.7 5.2 518.9 1105.5 185.6 757.5 0.4 79.9 57.0 6.0 91.5 218.5 36.8 2.1 77.8 4.6 420.7 21.5 31.8 448.3 302.1 44.1 12.5 203.2 0.4 1.6 46.1 98.5 33.4 425.1 678.2 3.8 0.9 2.2 4.7 6.1 10.1 11.6 387.4 46.8 0.9 34.6 241.4 6.5 12.4 58.7 1.9 4.3 0.0 1.0 1.0 0.6 88.6 374.9 1.5 15.7 632.1 260.0 3.5 159.3 0.2 0.0 38.4 32.4 8.8 26.3 1028.4 685.9 58.0 17.4 0.5 505.4 1495.5 KLHL18 "FLJ13703, KIAA0795" ENSG00000114648 "Kelch like family member 18" O94889 3 47282917-47346816 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035027, HPA035028" Approved Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 56: Bipolar cells - Visual perception" Nucleoplasm "Nuclear bodies" "HPA035027: AB_10602340, HPA035028: AB_10669899" "unprognostic (1.96e-1)" "unprognostic (1.61e-1)" "unprognostic (1.20e-1)" "unprognostic (3.82e-2)" "unprognostic (2.26e-1)" "unprognostic (3.47e-2)" "prognostic unfavorable (3.13e-4)" "unprognostic (1.22e-1)" "unprognostic (9.01e-2)" "unprognostic (3.05e-1)" "unprognostic (9.60e-2)" "unprognostic (3.23e-3)" "unprognostic (2.88e-3)" "unprognostic (3.13e-2)" "unprognostic (2.61e-1)" "unprognostic (1.07e-1)" "unprognostic (4.67e-1)" 5.9 6.2 6.5 6.2 6.9 15.9 4.6 5.9 7.7 5.7 3.9 5.8 4.4 5.3 5.1 8.7 4.6 5.4 6.2 6.8 6.3 6.1 3.7 6.2 6.9 4.9 6.0 3.9 5.5 7.2 6.0 5.5 5.1 5.1 4.6 20.2 4.4 6.2 6.7 13.8 5.6 6.6 5.5 8.8 4.9 6.3 6.7 5.1 7.0 5.6 7.5 6.7 6.7 6.3 11.6 14.6 11.1 16.5 12.0 8.6 7.9 15.6 8.1 15.5 12.6 15.6 7.0 22.6 8.6 13.1 14.2 7.0 33.7 16.5 15.9 18.0 11.3 33.3 20.9 14.3 12.3 17.9 14.7 10.0 12.5 22.4 20.8 8.7 17.5 12.1 41.0 9.2 12.6 9.6 13.7 10.3 20.4 9.4 29.2 9.4 7.3 13.2 14.6 21.6 7.6 10.1 10.9 13.2 7.9 11.3 7.8 9.7 18.4 14.3 14.8 16.6 19.9 10.3 21.9 19.5 9.2 20.5 15.4 6.1 12.1 3.7 2.0 10.7 2.9 3.8 1.6 3.9 7.8 2.4 1.3 2.0 4.9 1.3 18.6 2.0 1.7 5.7 6.5 6.9 5.9 7.7 6.8 6.3 4.9 6.0 5.1 5.5 6.7 6.3 19.6 12.8 13.7 13.1 24.4 11.3 10.6 8.1 12.0 65.2 17.4 13.0 62.1 4.3 7.5 3.7 20.9 10.6 26.1 15.2 21.5 15.5 3.0 15.5 24.8 16.1 9.5 21.7 24.2 14.8 11.9 9.3 12.2 27.5 36.1 11.0 14.3 19.7 29.6 13.5 23.0 11.1 4.1 28.8 14.9 3.5 5.9 26.7 0.0 18.7 22.4 13.9 8.2 15.1 17.4 17.7 10.6 8.2 12.0 9.3 9.8 28.2 6.3 54.2 6.6 19.5 13.5 13.9 14.8 14.8 21.0 14.1 20.8 15.4 10.3 13.0 KLK9 KLK-L3 ENSG00000213022 "Kallikrein related peptidase 9" Q9UKQ9 19 51002508-51009634 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "skin 1: 11.8" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "head and neck cancer: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HaCaT: 1.0" CAB025049 Enhanced "Secreted in other tissues" NA NA "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "CAB025049: " "unprognostic (3.22e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 11.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KNL1 "AF15Q14, CASC5, CT29, D40, hKNL-1, hSpc105, KIAA1570, MCPH4, PPP1R55, Spc7" ENSG00000137812 "Kinetochore scaffold 1" Q8NG31 15 40594020-40664342 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Cancer-related genes, Disease variant, Mental retardation, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "bone marrow: 5.3;lymphoid tissue: 7.4;testis: 16.9" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 8.5;Extravillous trophoblasts: 11.3;Granulosa cells: 22.8;Hofbauer cells: 7.1;Proximal tubular cells: 11.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "HPA026624, HPA049647" Enhanced Enhanced "Nucleoplasm,Nuclear bodies" Yes Yes "Cluster 21: B-cells - Adaptive immune response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nuclear bodies" "HPA026624: AB_10601696, HPA049647: AB_2680840" "unprognostic (5.35e-2)" "unprognostic (1.01e-1)" "unprognostic (5.59e-3)" "unprognostic (4.22e-2)" "unprognostic (1.59e-2)" "unprognostic (5.66e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (2.11e-4)" "unprognostic (2.06e-2)" "unprognostic (1.43e-1)" "unprognostic (3.20e-4)" "unprognostic (2.22e-2)" "unprognostic (1.93e-12)" "unprognostic (3.07e-2)" "unprognostic (3.08e-1)" "unprognostic (8.45e-2)" "unprognostic (7.36e-2)" 0.2 0.1 0.1 1.9 0.0 5.3 0.3 0.2 0.2 0.2 0.2 1.3 1.6 0.3 0.2 1.0 0.1 0.3 0.1 0.1 0.1 0.5 0.7 0.4 3.6 0.1 0.3 0.0 0.0 0.3 0.0 1.3 0.1 0.1 1.4 0.2 0.2 0.0 0.0 0.8 1.7 0.7 0.0 0.6 0.9 16.9 0.3 7.4 0.3 0.1 3.4 0.5 0.2 0.1 19.1 9.3 18.0 13.8 0.5 2.6 8.6 20.5 8.1 16.0 13.1 11.6 7.2 11.9 6.1 9.3 12.0 21.9 17.6 9.7 16.3 21.4 5.0 35.5 15.5 3.9 0.0 26.2 17.8 0.5 0.4 10.8 6.4 2.1 13.8 20.9 22.9 19.2 18.3 6.1 23.5 6.1 9.4 11.3 9.5 21.2 25.8 5.9 2.6 15.6 15.9 7.7 17.7 10.6 2.1 5.9 11.1 9.0 13.1 18.7 16.3 21.9 11.7 7.5 27.9 22.3 7.6 18.5 18.1 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.3 0.5 0.0 0.1 0.1 0.1 0.1 0.0 0.6 0.0 0.1 0.0 0.2 0.2 0.1 0.1 0.1 0.3 0.1 0.0 0.3 0.1 0.3 0.0 0.5 0.0 1.1 0.0 0.0 0.0 0.0 0.0 1.1 1.1 0.0 0.0 1.8 1.8 0.0 8.5 2.6 0.0 1.9 0.2 0.0 3.5 3.5 1.9 0.0 0.0 0.0 0.6 11.3 4.2 0.0 2.9 0.0 22.8 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 2.1 0.0 0.0 11.5 0.7 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 3.7 1.9 1.7 0.0 0.0 KPRP C1orf45 ENSG00000203786 "Keratinocyte proline rich protein" Q5T749 1 152759561-152762052 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "skin 1: 329.1" "Cell type enriched" "Detected in some" 11 "Suprabasal keratinocytes: 20.0" "Group enriched" "Detected in some" 22 "head and neck cancer: 6.9;melanoma: 13.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTEC/SVTERT24-B: 1.9;U-2197: 1.1" "Not detected" "Not detected" "HPA031988, HPA031990" Enhanced NA NA 27000000 "Cluster 61: Skin - Cornification" "Cluster 18: U-2197 - ECM organization" "Cluster 28: Keratinocytes - Keratinization" "HPA031988: AB_10671582, HPA031990: AB_2674102" "unprognostic (1.03e-1)" "unprognostic (2.67e-2)" "unprognostic (1.22e-1)" "unprognostic (1.03e-1)" 0.2 0.0 0.0 0.0 0.9 0.1 10.3 0.0 0.1 13.9 0.0 0.0 0.0 0.0 0.0 20.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 5.1 0.0 1.7 329.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 4.0 0.0 7.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.9 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.0 0.0 0.0 0.0 0.0 0.0 KRT1 "EHK1, KRT1A" ENSG00000167768 "Keratin 1" P04264 12 52674736-52680407 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Ichthyosis, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "skin 1: 13006.6" "Cell type enriched" "Detected in some" 5 "Suprabasal keratinocytes: 10030.4" "Group enriched" "Detected in many" 5 "head and neck cancer: 313.8;melanoma: 478.9" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "memory CD4 T-cell: 2.3" "Lineage enriched" "Detected in single" 23 "T-cells: 2.3" "Group enriched" "Detected in some" 14 "HaCaT: 94.9;hTCEpi: 39.3" "Low region specificity" "Detected in all" "Not detected" "Not detected" "CAB002153, HPA017917, HPA062908" Enhanced NA NA 35000000000 "Cluster 32: T-cells - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "CAB002153: AB_563790, HPA017917: AB_1852192, HPA062908: AB_2684901" "unprognostic (8.05e-2)" "unprognostic (8.49e-3)" "unprognostic (5.06e-3)" "unprognostic (6.44e-2)" "unprognostic (1.25e-2)" "unprognostic (1.53e-1)" "unprognostic (2.07e-1)" "unprognostic (3.24e-1)" "unprognostic (1.30e-1)" "unprognostic (2.16e-1)" "unprognostic (9.24e-2)" "unprognostic (6.63e-2)" "unprognostic (3.23e-4)" "unprognostic (1.58e-1)" "unprognostic (3.40e-2)" "unprognostic (1.36e-1)" "unprognostic (1.09e-2)" 10.3 1.4 0.0 0.1 0.0 7.7 464.1 0.0 0.1 473.6 0.0 2.6 0.2 1.3 0.4 30.8 0.4 0.3 4.5 0.0 0.0 1.2 3.5 2.6 0.0 0.0 0.0 1.4 3.7 0.0 1.4 1.6 0.0 1.5 0.1 0.0 270.2 0.1 47.8 13006.6 2.0 0.2 0.0 1.6 2.1 1.9 0.0 76.8 2.0 0.8 0.5 0.9 1257.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 94.9 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.7 0.0 39.3 0.0 0.0 0.0 0.0 4.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.8 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 1681.6 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.6 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 19.1 0.0 22.3 0.0 0.0 0.0 17.4 0.0 0.0 234.7 0.0 0.0 0.2 0.2 0.0 0.0 0.2 0.0 0.0 267.0 0.0 0.0 0.3 265.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 10.5 0.0 0.0 1.1 10030.4 0.0 7.8 0.0 0.3 0.4 KRT10 "CK10, K10, KPP" ENSG00000186395 "Keratin 10" P13645 17 40818117-40822614 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 14 "skin 1: 15851.5" "Cell type enriched" "Detected in all" 5 "Suprabasal keratinocytes: 12515.3" "Group enriched" "Detected in all" 4 "head and neck cancer: 310.0;melanoma: 562.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in many" 5 "hTCEpi: 718.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000132, HPA012014" Enhanced "Secreted in other tissues" NA NA 18000000000 "Cluster 37: B-cells - Transcription" "Cluster 61: Skin - Cornification" "Cluster 30: Epithelial cell lines - Translation" "Cluster 28: Keratinocytes - Keratinization" "CAB000132: , HPA012014: AB_1852195" "unprognostic (3.07e-1)" "unprognostic (5.19e-2)" "unprognostic (1.71e-1)" "unprognostic (1.37e-2)" "unprognostic (2.00e-2)" "unprognostic (2.60e-1)" "unprognostic (3.02e-2)" "unprognostic (1.29e-2)" "unprognostic (1.09e-1)" "unprognostic (1.56e-1)" "unprognostic (1.00e-2)" "unprognostic (2.14e-1)" "prognostic unfavorable (9.32e-5)" "unprognostic (1.64e-1)" "unprognostic (1.85e-1)" "unprognostic (1.66e-2)" "unprognostic (8.10e-2)" 66.1 47.9 9.4 7.6 9.8 13.4 432.0 9.9 14.9 548.0 10.4 45.2 7.9 55.0 5.5 78.6 45.5 2.2 95.7 9.9 9.8 67.2 64.5 39.7 6.2 9.8 9.7 52.3 69.1 8.2 77.2 3.8 9.8 60.0 3.4 6.9 163.9 5.5 123.1 15851.5 48.2 4.0 9.8 56.8 58.0 64.9 9.8 44.0 53.5 5.8 13.7 48.5 1106.2 10.4 30.3 31.2 11.0 12.2 14.4 11.5 10.4 29.9 16.5 11.4 10.6 11.2 11.7 8.7 42.0 13.1 16.2 158.5 5.4 11.3 13.4 20.1 27.0 9.2 44.7 19.4 16.4 17.1 24.9 10.1 718.0 9.0 17.3 15.0 7.4 12.3 102.1 16.0 12.2 17.3 25.5 16.2 14.6 23.1 19.1 17.8 16.7 17.7 12.3 26.3 8.9 11.1 19.9 46.0 39.0 17.3 35.5 24.3 9.3 17.6 29.5 22.5 34.4 0.4 19.8 22.4 24.5 10.4 23.4 12.8 2.6 11.1 4.8 2.3 5.4 11.2 5.4 6.8 4.1 5.6 5.8 5.9 0.8 6.9 3.2 8.1 5.5 1.9 9.4 9.8 9.9 14.9 9.9 9.8 9.8 9.7 9.8 9.8 9.8 10.4 197.8 35.3 40.0 19.2 187.5 2239.7 320.6 370.2 255.6 47.0 304.4 328.2 194.2 174.5 197.2 112.2 20.9 117.4 163.2 138.9 305.2 232.5 150.4 174.3 172.2 170.0 181.1 87.7 19.1 376.9 295.7 204.5 126.9 164.5 74.3 87.0 159.5 237.6 105.0 21.9 16.3 237.6 195.3 90.3 350.7 65.6 216.6 116.8 393.1 20.6 100.1 221.4 162.7 17.6 35.0 236.0 149.8 174.9 311.6 342.0 155.3 233.2 116.8 68.6 105.2 141.0 167.7 345.1 121.2 295.0 12515.3 160.1 164.3 131.4 173.1 515.6 KRT12 K12 ENSG00000187242 "Keratin 12" Q99456 17 40861303-40867223 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Corneal dystrophy, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "intestine: 1.0" "Group enriched" "Detected in some" 5 "Distal enterocytes: 3.9;Paneth cells: 12.8" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA055217, HPA055835" Enhanced NA NA "Cluster 31: Skin - Epidermis development" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA055217: AB_2682742, HPA055835: AB_2682935" "unprognostic (1.89e-1)" "unprognostic (2.40e-2)" "unprognostic (1.01e-1)" "unprognostic (4.82e-1)" "unprognostic (2.19e-1)" "unprognostic (2.04e-1)" "unprognostic (1.74e-2)" "unprognostic (5.52e-2)" "unprognostic (9.41e-3)" "unprognostic (3.49e-1)" "unprognostic (1.73e-1)" "unprognostic (3.94e-3)" "unprognostic (2.01e-2)" "unprognostic (1.27e-1)" "unprognostic (2.60e-4)" "unprognostic (6.31e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 1.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 12.8 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 KRT19 "CK19, K19, K1CS, MGC15366" ENSG00000171345 "Keratin 19" P08727 17 41523617-41528308 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 889.0;salivary gland: 810.7;urinary bladder: 781.4" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 7444.0;Club cells: 5055.9;Ductal cells: 4717.9;Extravillous trophoblasts: 6919.3;Pancreatic endocrine cells: 7374.9;Proximal enterocytes: 8623.3;Urothelial cells: 5959.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 1945.3;HBEC3-KT: 2945.0;MCF7: 2220.9;RT4: 3146.7;SK-BR-3: 5446.1;T-47d: 3674.2" "Not detected" "Not detected" "CAB000031, HPA002465" Enhanced Supported "Intermediate filaments" NA NA 300000000 "Cluster 40: NK-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Intermediate filaments" "CAB000031: AB_2234418, HPA002465: AB_1079179" "unprognostic (1.09e-1)" "unprognostic (1.83e-1)" "unprognostic (3.86e-2)" "unprognostic (1.59e-2)" "unprognostic (2.24e-2)" "unprognostic (1.13e-1)" "unprognostic (2.29e-1)" "unprognostic (2.80e-2)" "unprognostic (3.14e-1)" "unprognostic (4.86e-2)" "prognostic unfavorable (6.82e-5)" "unprognostic (1.90e-2)" "prognostic unfavorable (2.98e-5)" "unprognostic (3.52e-2)" "unprognostic (2.14e-1)" "unprognostic (3.08e-2)" "unprognostic (2.35e-2)" 89.3 18.7 2.0 61.7 2.4 0.3 403.3 7.9 2.5 250.0 1.6 525.7 348.3 57.9 72.0 889.0 176.1 298.6 13.5 1.5 1.7 141.8 7.7 204.1 0.4 1.6 2.9 74.4 48.8 14.3 15.6 175.1 2.2 208.3 359.2 0.1 810.7 194.2 1.3 141.9 776.1 46.5 1.4 1.2 631.5 3.4 1.8 127.8 28.3 1.6 98.3 781.4 317.0 1.8 2.6 343.4 0.0 6.3 0.7 1.8 1169.3 412.1 0.5 12.8 2.9 992.6 1945.3 0.4 393.3 199.0 1.5 1044.6 0.1 2945.0 2.5 0.8 10.4 0.2 213.4 692.3 30.3 0.0 82.0 0.7 524.9 9.0 0.4 0.2 26.2 0.0 148.4 2.5 0.1 2220.9 5.9 3.0 18.5 1323.5 492.7 2.9 0.1 5.8 1335.4 3146.7 40.0 1.7 3.3 5446.1 0.1 266.5 3674.2 0.3 1.7 3.6 6.1 7.7 0.7 1.1 0.8 2.0 1.5 0.3 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 2.0 2.4 7.9 2.5 1.5 1.7 1.6 2.9 2.2 1.4 1.8 1.8 10.5 673.1 185.5 0.0 17.8 5.2 4317.3 7444.0 1715.8 0.0 1393.0 867.5 2.9 662.0 5055.9 892.0 0.0 1160.8 20.5 3599.6 1.9 4717.9 0.1 737.2 102.8 41.9 362.5 0.0 0.1 2589.9 6919.3 171.8 1571.4 1010.7 94.6 1.0 1.1 0.7 179.0 0.0 0.1 1382.4 2720.0 2.6 2.5 2.6 37.9 25.5 190.3 1.0 30.0 0.8 0.0 0.0 0.0 7374.9 3399.6 88.8 19.9 2228.8 8623.3 26.7 1954.3 0.0 0.0 0.0 240.0 1.1 1.6 1302.6 1.1 2127.5 36.1 4.8 1619.0 5959.8 KRT23 "CK23, DKFZP434G032, HAIK1, K23, MGC26158" ENSG00000108244 "Keratin 23" Q9C075 17 40922700-40937646 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "salivary gland: 147.7;skin 1: 172.3" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 1328.6;Cytotrophoblasts: 679.8;Prostatic glandular cells: 2203.0;Syncytiotrophoblasts: 3890.8;Urothelial cells: 1590.3" "Cancer enhanced" "Detected in many" "urothelial cancer: 61.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 14 "HBEC3-KT: 9.6;Hep G2: 11.0;SuSa: 7.1;T-47d: 16.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA012050, HPA016959, CAB017091" Approved Approved "Intermediate filaments,Cytosol" NA NA 590000 "Cluster 52: Eosinophils - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 6: T47d - Mammary gland" "Cluster 22: Epithelial cell types - Mixed function" "Intermediate filaments" Cytosol "CAB017091: , HPA012050: AB_1852226, HPA016959: AB_1852228" "unprognostic (1.62e-1)" "unprognostic (5.29e-2)" "unprognostic (4.35e-2)" "unprognostic (6.18e-3)" "unprognostic (1.45e-2)" "unprognostic (2.83e-1)" "unprognostic (5.22e-2)" "unprognostic (6.84e-3)" "unprognostic (2.74e-1)" "unprognostic (2.15e-2)" "unprognostic (8.96e-2)" "unprognostic (1.56e-1)" "unprognostic (8.22e-2)" "unprognostic (6.78e-2)" "unprognostic (1.40e-1)" "unprognostic (2.99e-1)" "prognostic unfavorable (8.26e-4)" 0.4 0.0 0.0 0.3 0.0 1.1 15.7 0.0 0.0 6.8 0.0 0.1 0.2 1.1 2.1 6.5 3.0 1.5 0.2 0.0 0.0 0.6 1.0 1.4 0.0 0.0 0.0 0.1 3.6 0.1 2.8 15.6 0.0 20.7 0.0 0.6 147.7 0.4 0.3 172.3 0.2 0.0 0.0 3.0 0.2 21.7 0.0 0.4 0.1 0.4 2.5 4.4 10.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.1 0.0 0.0 0.2 0.0 9.6 0.0 0.0 0.0 0.0 0.1 11.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.6 0.0 7.1 16.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.3 0.3 0.3 4.6 1328.6 242.1 0.6 0.0 78.0 27.9 0.4 12.8 390.5 3.7 0.0 679.8 1.1 0.1 1.9 462.9 66.2 49.8 7.8 15.1 7.1 0.0 0.5 0.8 109.3 15.0 0.0 66.4 0.0 0.0 0.0 0.0 63.8 0.0 0.3 0.7 57.0 0.0 0.7 10.6 0.6 3.0 5.4 0.0 5.4 15.8 0.0 0.5 0.3 17.7 1.1 0.7 0.0 2203.0 0.0 0.4 275.0 0.2 0.0 0.0 48.4 62.1 0.7 7.9 8.1 3890.8 7.6 0.1 0.9 1590.3 KRT24 "FLJ20261, MGC138169, MGC138173" ENSG00000167916 "Keratin 24" Q2M2I5 17 40697991-40703752 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "esophagus: 178.0;lymphoid tissue: 76.3" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 6.0;Fibroblasts: 4.6;Leydig cells: 3.1;Syncytiotrophoblasts: 4.0" "Group enriched" "Detected in some" 4 "cervical cancer: 9.6;head and neck cancer: 15.0;urothelial cancer: 6.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 14 "SK-BR-3: 7.0" "Region enriched" "Detected in single" 10 "cerebellum: 1.0" "Low region specificity" "Detected in some" HPA022978 Uncertain Approved "Intermediate filaments,Cytosol" No NA 300000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "Intermediate filaments, Cytosol" "HPA022978: AB_1852230" "unprognostic (2.74e-2)" "unprognostic (1.05e-2)" "unprognostic (1.45e-1)" "unprognostic (3.16e-2)" "unprognostic (2.47e-1)" "unprognostic (3.75e-1)" "unprognostic (2.74e-1)" "unprognostic (2.95e-1)" "unprognostic (3.37e-2)" 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 5.3 0.0 8.0 0.0 0.1 16.7 178.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.5 0.0 0.0 5.8 0.2 2.2 1.6 0.0 0.0 0.3 0.5 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 76.3 2.6 13.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 1.2 4.6 0.0 0.7 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.1 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 4.0 0.0 0.0 0.0 0.0 KRT7 "CK7, K2C7, K7, SCL" ENSG00000135480 "Keratin 7" P08729 12 52232520-52252186 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 905.8;thyroid gland: 593.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1756.7;Ductal cells: 2931.3;Exocrine glandular cells: 2143.5;Extravillous trophoblasts: 4196.1;Pancreatic endocrine cells: 6163.7;Prostatic glandular cells: 2386.6;Urothelial cells: 1900.8" "Cancer enhanced" "Detected in many" "urothelial cancer: 560.1" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 4 "intermediate monocyte: 1.1" "Lineage enriched" "Detected in single" 4 "monocytes: 1.1" "Cell line enhanced" "Detected in many" "A549: 2418.2;BEWO: 2737.9;HBEC3-KT: 6225.3;hTERT-HME1: 2433.8;RT4: 7463.2;SiHa: 5833.6;SK-BR-3: 3363.4" "Not detected" "Not detected" "Not detected" "Not detected" "CAB000028, HPA007272, HPA007315, CAB079970" Enhanced Approved "Intermediate filaments,Cytosol" NA NA 1300000000 "Cluster 7: Monocytes - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 15: RT4 - Unknown function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Intermediate filaments" Cytosol "CAB000028: AB_2134589, CAB079970: , HPA007272: AB_1079181, HPA007315: " "unprognostic (2.71e-3)" "unprognostic (3.09e-1)" "unprognostic (2.20e-1)" "prognostic unfavorable (1.99e-4)" "unprognostic (2.22e-2)" "unprognostic (8.59e-2)" "unprognostic (1.27e-1)" "unprognostic (5.44e-3)" "unprognostic (2.74e-1)" "prognostic unfavorable (9.42e-5)" "prognostic unfavorable (7.78e-5)" "unprognostic (4.54e-2)" "prognostic favorable (2.77e-9)" "unprognostic (2.82e-1)" "unprognostic (1.43e-2)" "unprognostic (3.28e-1)" "unprognostic (3.98e-3)" 27.1 0.7 0.0 1.4 0.0 0.3 272.9 0.0 0.2 48.4 0.0 1.6 0.4 12.9 15.2 91.7 75.9 82.4 5.6 0.0 0.0 147.5 14.2 325.2 1.7 0.2 0.0 2.4 57.4 5.6 12.0 265.1 0.2 58.1 0.7 0.3 905.8 213.2 1.7 78.3 1.3 0.4 0.1 0.8 17.8 0.8 0.1 3.3 593.0 2.0 6.7 389.8 20.1 0.4 4.9 2418.2 0.6 1.7 2.8 0.0 2737.9 509.6 0.6 261.3 23.6 7.6 1683.1 0.3 1.4 176.3 0.8 1871.6 0.2 6225.3 13.3 3.0 0.0 2.2 1179.8 8.0 57.4 1.5 1.5 1.3 380.7 1.3 2433.8 1.0 267.4 0.0 0.7 2.2 0.1 13.7 1.8 3.7 7.6 1.1 2.6 2.0 4.8 38.6 1520.5 7463.2 3.5 2.4 5833.6 3363.4 0.0 27.5 130.3 0.0 2028.2 1.9 3.7 2.4 1.1 1.8 0.4 2.0 2.0 1.6 1.2 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.2 0.1 0.1 0.4 8.1 653.9 109.4 0.0 2.5 3.6 1172.6 173.6 8.0 0.0 451.3 426.3 0.8 724.9 684.8 360.5 0.0 1756.7 8.9 2.2 135.0 2931.3 16.1 106.2 20.4 30.6 6.6 0.0 0.1 2143.5 4196.1 29.9 14.3 253.2 3.8 0.1 4.2 2.9 189.9 0.0 0.0 3.5 954.2 3.4 4.6 140.0 3.7 11.0 131.6 0.0 35.6 0.0 0.0 0.0 0.0 6163.7 0.3 0.4 1.4 2386.6 0.2 8.5 249.2 0.0 0.0 7.6 72.1 0.6 1.3 35.3 2.3 1442.5 9.2 0.0 4.4 1900.8 KRT79 "K6L, KRT6L" ENSG00000185640 "Keratin 79" Q5XKE5 12 52821408-52834311 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "skin 1: 68.3" "Cell type enhanced" "Detected in some" "granulocytes: 4.5;Late spermatids: 1.1;Melanocytes: 3.6" "Group enriched" "Detected in some" 5 "breast cancer: 1.4;cervical cancer: 2.6;head and neck cancer: 2.7;melanoma: 1.6;urothelial cancer: 3.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 19 "HMC-1: 425.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA059347 Enhanced Approved "Nucleoplasm,Nuclear membrane,Cytosol" NA NA 1900000000 "Cluster 61: Skin - Cornification" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "Nucleoplasm, Nuclear membrane, Cytosol" "HPA059347: AB_2683986" "unprognostic (5.19e-3)" "unprognostic (1.56e-3)" "unprognostic (5.24e-2)" "unprognostic (2.38e-2)" "unprognostic (6.85e-2)" "unprognostic (6.36e-2)" "unprognostic (3.17e-1)" "unprognostic (7.92e-2)" "unprognostic (1.88e-2)" "unprognostic (1.60e-2)" "unprognostic (1.32e-1)" "unprognostic (2.72e-1)" "unprognostic (3.99e-2)" 0.1 0.0 0.0 0.0 0.0 0.1 3.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 68.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 425.5 0.0 0.0 5.1 0.0 0.4 0.0 0.0 0.0 0.5 0.0 0.0 0.1 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 21.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 4.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 1.1 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 KRT8 "CARD2, CK8, CYK8, K2C8, K8, KO" ENSG00000170421 "Keratin 8" P05787 12 52897187-52949954 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1335.5;stomach 1: 800.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 4302.8;Ductal cells: 6037.3;Exocrine glandular cells: 5457.6;Extravillous trophoblasts: 5323.4;Pancreatic endocrine cells: 5278.1;Paneth cells: 4937.3;Proximal enterocytes: 6802.6;Syncytiotrophoblasts: 5268.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 1.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A549: 6130.6;BEWO: 3998.7;CACO-2: 7686.4;CAPAN-2: 4774.8;MCF7: 10521.8;SK-BR-3: 5126.4;T-47d: 4325.7" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 10 "spinal cord: 44.0" "CAB000131, CAB001696, HPA049866" Enhanced Supported "Intermediate filaments" NA NA 1700000000 "Cluster 15: NK-cells - Transcription" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Intermediate filaments" "CAB000131: AB_2281144, CAB001696: , HPA049866: AB_2680923" "unprognostic (5.72e-2)" "unprognostic (2.29e-1)" "unprognostic (2.49e-2)" "unprognostic (1.52e-1)" "unprognostic (2.76e-2)" "unprognostic (4.86e-3)" "unprognostic (3.10e-2)" "unprognostic (2.52e-2)" "unprognostic (1.92e-1)" "unprognostic (4.58e-1)" "prognostic unfavorable (1.51e-4)" "unprognostic (8.99e-2)" "unprognostic (2.08e-2)" "unprognostic (2.83e-2)" "unprognostic (3.18e-1)" "unprognostic (3.68e-1)" "unprognostic (1.19e-2)" 135.0 43.6 2.2 158.6 1.3 1.0 113.8 2.0 1.6 183.4 21.3 1079.2 1112.0 34.7 66.4 48.2 134.3 217.5 147.8 1.9 1.9 240.2 463.9 172.5 7.9 8.3 4.5 10.3 654.1 59.9 278.7 368.7 8.8 151.6 564.2 0.4 318.0 73.6 1.5 49.3 1335.5 50.6 0.4 16.3 800.1 7.6 4.9 47.6 237.5 0.3 13.8 209.0 36.7 1.7 2787.7 6130.6 0.2 7.8 0.7 3.2 3998.7 11.1 47.9 6.1 6.3 7686.4 4774.8 1.1 1130.2 14.7 6.9 947.1 17.6 752.6 5.9 4.6 130.8 4.3 1184.4 2234.2 212.8 1.2 2.4 9.5 12.6 14.8 50.8 419.9 17.0 1.0 484.7 1.7 0.1 10521.8 6.5 10.6 418.5 2740.6 132.8 3.8 2.2 15.2 1198.1 1354.5 129.9 5.0 1063.2 5126.4 7.8 1263.8 4325.7 10.5 18.8 5.7 443.4 9.3 10.0 1.6 7.0 7.6 3.3 1.7 13.4 1.3 0.1 0.2 0.2 0.2 0.1 0.1 0.1 0.1 0.7 0.2 0.1 0.1 0.4 0.5 0.1 1.7 0.1 0.2 2.2 1.3 2.0 1.6 1.9 1.9 8.3 4.5 8.8 0.4 4.9 1.7 7.7 400.6 176.5 0.3 26.9 6.0 1948.0 684.7 303.3 2.3 521.6 342.8 30.2 1069.5 734.8 491.1 0.0 2208.2 8.5 4302.8 297.4 6037.3 13.9 419.2 41.0 42.3 942.5 8.6 0.5 5457.6 5323.4 94.7 1740.1 557.1 76.3 88.0 24.3 310.9 252.2 1.7 0.5 2876.3 1625.5 9.9 7.2 69.9 8.1 22.2 131.6 0.0 55.0 3.4 1.0 1.0 0.3 5278.1 4937.3 1.9 6.6 994.7 6802.6 569.1 594.8 4.3 0.0 2.2 167.4 2.0 11.4 258.9 1.7 5268.8 33.4 13.4 2337.3 1542.5 LACRT LACRITIN ENSG00000135413 Lacritin Q9GZZ8 12 54630811-54634895 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 16 "salivary gland: 13.2" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 304 "breast cancer: 15.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to digestive system" NA NA 230000 "Cluster 24: Salivary gland - Salivary secretion" 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LCE1A LEP1 ENSG00000186844 "Late cornified envelope 1A" Q5T7P2 1 152827473-152828097 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "skin 1: 269.6" "Cell type enriched" "Detected in some" 14 "Suprabasal keratinocytes: 40.3" "Cancer enriched" "Detected in some" 6 "melanoma: 14.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" "Cluster 28: Keratinocytes - Keratinization" "unprognostic (3.82e-2)" "unprognostic (1.70e-1)" 0.1 0.0 0.0 0.0 0.0 0.0 23.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 269.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 40.3 0.0 0.1 0.0 0.0 0.0 LCE1B "LEP2, SPRL2A" ENSG00000196734 "Late cornified envelope 1B" Q5T7P3 1 152811971-152813108 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "skin 1: 167.5" "Cell type enriched" "Detected in some" 18 "Suprabasal keratinocytes: 18.9" "Cancer enriched" "Detected in some" 10 "melanoma: 6.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "hTCEpi: 2.0" NA NA "Cluster 61: Skin - Cornification" "Cluster 30: Epithelial cell lines - Translation" "Cluster 28: Keratinocytes - Keratinization" "unprognostic (1.79e-1)" "unprognostic (1.24e-2)" "unprognostic (6.43e-2)" 0.1 0.0 0.0 0.0 0.0 0.0 15.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 167.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 18.9 0.0 0.0 0.0 0.0 0.0 LCE1C LEP3 ENSG00000197084 "Late cornified envelope 1C" Q5T751 1 152804835-152806628 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "skin 1: 596.1" "Cell type enriched" "Detected in some" 4 "Suprabasal keratinocytes: 83.0" "Cancer enriched" "Detected in some" 6 "melanoma: 17.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "BJ hTERT+: 1.0;HBEC3-KT: 2.2;hTEC/SVTERT24-B: 1.1;hTERT-HME1: 2.8" NA NA "Cluster 61: Skin - Cornification" "Cluster 30: Epithelial cell lines - Translation" "Cluster 28: Keratinocytes - Keratinization" "unprognostic (3.35e-2)" "unprognostic (5.95e-2)" "unprognostic (3.46e-2)" "unprognostic (3.35e-2)" 0.3 0.1 0.0 0.0 0.0 0.3 34.1 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.3 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.0 4.1 596.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.1 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.4 0.0 3.5 2.8 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.6 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.2 83.0 0.0 0.2 0.0 0.0 0.0 LCE1D LEP4 ENSG00000172155 "Late cornified envelope 1D" Q5T752 1 152796721-152798181 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 93 "skin 1: 80.8" "Cell type enriched" "Detected in single" 42 "Suprabasal keratinocytes: 12.6" "Cancer enriched" "Detected in single" 8 "melanoma: 4.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" "Cluster 28: Keratinocytes - Keratinization" "unprognostic (7.67e-2)" 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 80.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.6 0.0 0.0 0.0 0.0 0.0 LCE1E LEP5 ENSG00000186226 "Late cornified envelope 1E" Q5T753 1 152786214-152788426 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 38 "skin 1: 61.4" "Cell type enriched" "Detected in some" 10 "Suprabasal keratinocytes: 18.3" "Cancer enhanced" "Detected in single" "melanoma: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "HaCaT: 10.0" NA NA "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "unprognostic (9.92e-2)" "unprognostic (9.50e-2)" "unprognostic (2.30e-2)" "unprognostic (2.56e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 61.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.5 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.0 10.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 18.3 0.0 0.1 0.0 0.0 0.0 LCE1F LEP6 ENSG00000240386 "Late cornified envelope 1F" Q5T754 1 152776372-152776728 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "skin 1: 209.8" "Cell type enriched" "Detected in some" 10 "Suprabasal keratinocytes: 18.3" "Group enriched" "Detected in some" 13 "head and neck cancer: 5.5;melanoma: 14.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "BJ hTERT+: 6.5;hTERT-HME1: 3.0" NA NA "Cluster 61: Skin - Cornification" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 28: Keratinocytes - Keratinization" "unprognostic (2.21e-1)" "unprognostic (8.43e-2)" 0.0 0.0 0.0 0.0 0.0 0.2 8.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 209.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 6.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.3 0.0 0.0 0.0 0.0 0.0 LCE2A LEP9 ENSG00000187173 "Late cornified envelope 2A" Q5TA79 1 152698345-152699442 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "skin 1: 118.2" "Cell type enriched" "Detected in single" 4 "Melanocytes: 1.8" "Cancer enriched" "Detected in some" 5 "melanoma: 10.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 5.6;SK-MEL-30: 2.0;U-2197: 1.4" NA NA "Cluster 61: Skin - Cornification" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (3.45e-2)" "unprognostic (6.77e-2)" 0.0 0.0 0.0 0.0 0.0 0.1 8.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.4 118.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.9 0.0 1.4 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 LCE2B "LEP10, SPRL1B, XP5" ENSG00000159455 "Late cornified envelope 2B" O14633 1 152686123-152687397 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "skin 1: 719.8" "Cell type enriched" "Detected in some" 17 "Suprabasal keratinocytes: 31.5" "Cancer enriched" "Detected in some" 5 "melanoma: 11.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" "Cluster 28: Keratinocytes - Keratinization" "unprognostic (3.04e-2)" "unprognostic (1.36e-1)" 0.5 0.1 0.0 0.0 0.0 0.0 42.4 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 6.1 719.8 0.1 0.0 0.0 0.1 0.1 0.2 0.0 0.2 0.1 0.0 0.9 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 31.5 0.0 0.1 0.0 0.0 0.0 LCE2C LEP11 ENSG00000187180 "Late cornified envelope 2C" Q5TA81 1 152675295-152676574 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "skin 1: 321.2" "Cell type enriched" "Detected in single" 35 "Suprabasal keratinocytes: 14.2" "Cancer enriched" "Detected in some" 5 "melanoma: 9.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" "Cluster 28: Keratinocytes - Keratinization" "unprognostic (1.47e-2)" "unprognostic (7.00e-2)" 0.2 0.0 0.0 0.0 0.0 0.1 22.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 321.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 1.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.2 0.0 0.0 0.0 0.0 0.0 LCE2D "LEP12, SPRL1A" ENSG00000187223 "Late cornified envelope 2D" Q5TA82 1 152663380-152664659 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "skin 1: 152.1" "Group enriched" "Detected in some" 8 "Melanocytes: 1.8;Suprabasal keratinocytes: 4.7" "Group enriched" "Detected in some" 42 "head and neck cancer: 1.2;melanoma: 4.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" "Cluster 28: Keratinocytes - Keratinization" "unprognostic (3.94e-2)" "unprognostic (5.63e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 152.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 LCE4A "LEP8, SPRL4A" ENSG00000187170 "Late cornified envelope 4A" Q5TA78 1 152708160-152709491 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "skin 1: 3.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" "unprognostic (1.61e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LCE5A "LEP18, SPRL5A" ENSG00000186207 "Late cornified envelope 5A" Q5TCM9 1 152510803-152512177 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skin 1: 91.5" "Cell type enriched" "Detected in some" 4 "Suprabasal keratinocytes: 7.4" "Cancer enhanced" "Detected in single" "melanoma: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" "Cluster 28: Keratinocytes - Keratinization" "unprognostic (2.51e-1)" "unprognostic (7.27e-3)" "unprognostic (9.27e-2)" "unprognostic (1.89e-1)" 0.0 0.0 0.0 0.0 0.0 0.1 11.7 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 91.5 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 0.0 0.0 0.0 0.0 0.0 LCE6A C1orf44 ENSG00000235942 "Late cornified envelope 6A" A0A183 1 152842856-152843983 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "skin 1: 246.6" "Cell type enriched" "Detected in single" 8 "Suprabasal keratinocytes: 2.6" "Cancer enriched" "Detected in some" 5 "melanoma: 5.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA046376 Enhanced NA NA "Cluster 61: Skin - Cornification" "Cluster 28: Keratinocytes - Keratinization" "HPA046376: AB_10965998" "unprognostic (4.25e-2)" "unprognostic (8.73e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 19.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 246.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 LDHD ENSG00000166816 "Lactate dehydrogenase D" Q86WU2 16 75111860-75116780 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 85.6;liver: 135.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 37.3;Distal enterocytes: 80.2;Distal tubular cells: 37.2;Hepatocytes: 88.6;Proximal tubular cells: 118.1" "Cancer enhanced" "Detected in all" "liver cancer: 32.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 11.1" "Group enriched" "Detected in many" 45 "granulocytes: 11.1;monocytes: 4.8" "Cell line enhanced" "Detected in many" "Hep G2: 11.4;HMC-1: 14.4;T-47d: 29.1;U-266/70: 11.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041766, HPA048639, HPA066148" Enhanced Approved Cytosol No NA "Cluster 34: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA041766: AB_2677660, HPA048639: AB_2680473, HPA066148: AB_2685626" "unprognostic (8.75e-2)" "unprognostic (3.68e-3)" "unprognostic (1.27e-1)" "unprognostic (5.28e-2)" "unprognostic (1.57e-1)" "unprognostic (1.53e-1)" "prognostic favorable (5.61e-4)" "unprognostic (2.49e-3)" "unprognostic (1.91e-1)" "unprognostic (2.72e-1)" "unprognostic (3.74e-1)" "unprognostic (4.01e-1)" "prognostic favorable (2.95e-14)" "unprognostic (4.10e-3)" "unprognostic (4.49e-2)" "unprognostic (7.00e-2)" "unprognostic (2.20e-1)" 24.9 14.4 17.7 2.1 19.7 0.7 11.7 20.5 22.6 5.4 34.1 27.2 8.8 3.5 1.1 10.8 5.5 3.0 85.6 16.1 18.9 36.1 135.5 4.9 0.8 20.8 20.2 16.4 18.7 17.0 11.8 0.7 22.4 8.1 9.7 1.3 21.3 3.2 68.7 5.8 5.7 1.2 17.0 1.1 23.1 1.7 19.3 0.5 10.6 52.7 0.6 2.6 3.7 17.5 0.7 2.1 0.0 0.2 1.6 1.4 6.1 0.2 0.1 0.2 0.2 2.8 2.6 0.1 2.1 0.9 1.0 0.3 0.0 0.1 0.0 0.0 0.2 0.1 0.8 11.4 2.6 0.0 14.4 2.0 0.3 0.0 0.0 0.6 0.1 0.4 0.7 2.5 0.0 5.3 0.1 0.8 1.4 2.7 1.3 0.0 0.0 7.8 1.4 0.1 0.0 0.0 0.2 5.2 0.3 0.7 29.1 3.3 0.0 0.0 0.2 0.0 0.0 11.5 0.6 0.0 1.9 0.1 0.0 11.1 2.2 0.6 0.0 3.6 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.8 17.7 19.7 20.5 22.6 16.1 18.9 20.8 20.2 22.4 17.0 19.3 17.5 1.6 0.0 6.7 7.8 1.0 0.6 1.8 2.2 0.6 0.5 6.5 2.4 37.3 11.5 2.3 11.0 0.0 2.1 0.1 80.2 37.2 2.3 0.4 2.2 0.3 1.7 3.0 2.7 1.0 6.2 1.2 2.3 32.6 3.8 10.2 2.1 4.2 88.6 7.2 1.7 1.4 11.0 0.0 6.0 1.0 0.6 0.0 3.0 5.4 1.9 2.0 12.0 0.0 1.0 3.2 3.0 28.3 0.0 0.8 2.1 2.4 118.1 2.0 1.4 0.0 4.1 1.3 0.0 0.7 3.6 0.3 3.1 1.0 1.8 15.7 1.5 LGALS7B GAL7 ENSG00000178934 "Galectin 7B" P47929 19 38789200-38791754 "Plasma proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 6695.7" "Group enriched" "Detected in many" 10 "Basal keratinocytes: 1529.6;Suprabasal keratinocytes: 5136.5" "Cancer enhanced" "Detected in many" "cervical cancer: 142.7;head and neck cancer: 185.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 20 "HaCaT: 3.9;OE19: 3.9" "HPA001549, CAB025100" Supported "Intracellular and membrane" NA NA 4000000 "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "CAB025100: , HPA001549: AB_1078938" "unprognostic (4.20e-2)" "unprognostic (2.15e-1)" "unprognostic (4.10e-2)" "prognostic unfavorable (1.59e-4)" "unprognostic (1.81e-1)" "unprognostic (3.54e-2)" "unprognostic (2.78e-2)" "unprognostic (1.01e-1)" "unprognostic (5.92e-2)" "unprognostic (3.66e-3)" "unprognostic (6.17e-2)" "unprognostic (2.93e-2)" "unprognostic (1.60e-1)" "unprognostic (1.21e-1)" "unprognostic (3.20e-2)" "unprognostic (1.29e-3)" 6.1 1.0 0.0 0.0 0.0 0.1 7.3 0.0 0.0 490.5 0.0 1.8 0.0 1.0 0.0 1463.3 0.9 0.0 2.6 0.0 0.0 2.1 3.0 2.6 0.0 0.0 0.0 1.4 2.7 0.0 2.2 0.0 0.0 5.0 0.0 0.0 167.2 0.1 10.2 6695.7 1.7 0.0 0.0 22.0 3.0 4.9 0.0 0.2 2.3 0.0 1.6 1.0 834.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 1529.6 6.3 253.5 102.4 0.0 1.2 13.3 0.4 0.0 64.4 1.8 0.0 0.0 0.0 0.3 0.0 0.0 5.4 3.1 0.2 3.2 1.2 0.0 0.0 0.2 0.1 3.4 0.0 1.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 22.4 0.0 41.3 12.3 0.0 0.3 44.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.4 0.0 2.1 0.3 0.3 9.3 0.0 0.0 1.3 4.2 7.5 1.9 329.6 5136.5 0.0 1.6 0.4 0.1 14.0 LORICRIN LOR ENSG00000203782 "Loricrin cornified envelope precursor protein" P23490 1 153259687-153262124 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Keratinization "Ichthyosis, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 76 "skin 1: 1842.9" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 11 "melanoma: 45.5" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 92 "HDLM-2: 35.2" "HPA076123, HPA077266" Enhanced NA NA 1800000 "Cluster 61: Skin - Cornification" "Cluster 44: HDLM-2 - Immune response" "Cluster 41: Macrophages - Immune response" "HPA076123: AB_2732302, HPA077266: AB_2732338" "unprognostic (1.97e-2)" "unprognostic (1.93e-2)" "unprognostic (4.16e-2)" "prognostic favorable (8.53e-4)" "unprognostic (1.65e-1)" "unprognostic (2.69e-1)" "unprognostic (1.61e-1)" "unprognostic (3.41e-1)" "unprognostic (1.47e-1)" "unprognostic (3.03e-1)" "unprognostic (1.02e-2)" 1.1 0.2 0.5 0.2 0.4 0.0 24.2 0.2 0.4 0.8 0.0 0.5 0.0 0.2 0.0 0.7 0.0 0.0 0.7 0.4 0.9 0.2 0.8 0.4 0.1 0.7 0.5 0.5 0.6 0.0 0.2 0.0 0.5 0.2 0.0 0.0 1.7 0.0 10.9 1842.9 0.4 0.0 0.5 0.4 0.3 0.5 1.0 0.6 0.3 0.0 1.8 0.1 21.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 35.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.2 0.4 0.4 0.9 0.7 0.5 0.5 0.5 1.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LPO SPO ENSG00000167419 Lactoperoxidase P22079 17 58218548-58268518 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrogen peroxide" "Antimicrobial, Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 404 "salivary gland: 1026.8" "Group enriched" "Detected in some" 6 "Breast glandular cells: 25.2;Early spermatids: 8.3;Late spermatids: 14.1" "Not detected" "Not detected" "Region enriched" "Detected in single" 4 "midbrain: 2.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 10 "THP-1: 9.9" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA028688 Enhanced Supported "Secreted to digestive system" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 43: THP-1 - Innate immune response" "Cluster 30: Mammary glandular cells - Lactation" "HPA028688: AB_10601909" "unprognostic (2.74e-1)" "unprognostic (5.12e-2)" "unprognostic (4.14e-3)" "unprognostic (1.56e-3)" "unprognostic (2.41e-2)" "unprognostic (9.71e-2)" "unprognostic (2.06e-2)" "unprognostic (1.53e-1)" "unprognostic (2.40e-2)" "unprognostic (6.27e-3)" "unprognostic (6.32e-2)" "unprognostic (2.56e-1)" "unprognostic (0.00e+0)" "unprognostic (3.41e-2)" "unprognostic (3.15e-1)" "unprognostic (2.72e-2)" "unprognostic (1.22e-1)" 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 2.5 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1026.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.3 0.0 2.5 0.0 0.0 0.5 0.1 0.2 0.0 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.7 25.2 0.5 0.7 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.1 8.3 0.3 0.1 0.3 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.1 1.3 0.0 0.4 0.0 0.2 1.7 0.3 0.0 0.0 0.0 0.0 14.1 0.3 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.3 0.0 0.4 0.0 0.5 1.4 0.1 0.0 0.3 0.0 0.2 0.1 2.6 0.4 0.0 0.3 0.0 0.2 0.0 0.5 0.5 LST1 "B144, D6S49E, LST-1" ENSG00000204482 "Leukocyte specific transcript 1" O00453 6 31586124-31588909 "Predicted intracellular proteins, Predicted membrane proteins" "Cell shape, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "bone marrow: 100.3;lung: 48.8;lymphoid tissue: 181.9" "Group enriched" "Detected in many" 11 "Hofbauer cells: 407.1;Kupffer cells: 1326.9;Langerhans cells: 1240.5;Macrophages: 871.6;monocytes: 1096.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 1746.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 39.3;HMC-1: 73.6;MOLT-4: 39.6;NB-4: 76.2;THP-1: 179.9;U-937: 92.9" "Low region specificity" "Detected in all" HPA079451 Supported "Plasma membrane,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane, Cytosol" "HPA079451: " "unprognostic (1.08e-2)" "prognostic favorable (7.89e-4)" "unprognostic (6.99e-2)" "unprognostic (4.16e-3)" "unprognostic (3.13e-1)" "unprognostic (3.92e-2)" "unprognostic (3.65e-1)" "unprognostic (7.06e-3)" "unprognostic (2.81e-3)" "unprognostic (2.12e-1)" "unprognostic (1.70e-1)" "unprognostic (1.28e-1)" "prognostic unfavorable (5.97e-5)" "unprognostic (1.47e-1)" "prognostic unfavorable (7.62e-4)" "unprognostic (1.03e-1)" "unprognostic (1.95e-1)" 15.2 10.2 4.3 22.0 4.3 100.3 7.9 4.6 7.2 5.6 5.0 7.9 7.1 3.7 1.4 5.5 6.6 3.1 7.6 4.6 5.5 10.8 14.4 48.8 13.8 6.1 4.9 3.0 4.7 0.9 6.1 4.7 6.6 8.9 3.0 0.5 6.9 2.3 2.1 7.8 15.0 5.1 5.4 181.9 5.7 1.8 5.2 15.1 4.6 1.9 7.1 9.1 5.1 6.0 0.3 0.6 0.0 0.8 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.2 2.5 0.6 0.0 0.0 0.5 0.3 0.4 0.3 12.9 0.0 39.3 0.0 0.0 0.7 29.3 73.6 0.0 0.3 0.1 1.2 0.3 0.9 0.8 0.1 0.2 0.0 0.0 39.6 76.2 0.1 0.0 0.0 18.4 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 179.9 0.3 0.0 0.4 0.0 0.2 0.1 0.0 5.9 0.0 92.9 0.0 112.2 419.7 681.6 9.4 1273.9 80.7 32.8 15.9 20.2 392.9 21.9 10.9 9.0 1133.0 21.6 1746.7 69.9 12.0 541.6 4.3 4.3 4.6 7.2 4.6 5.5 6.1 4.9 6.6 5.4 5.2 6.0 5.4 35.3 86.7 0.7 43.7 35.2 0.3 0.2 0.0 0.3 3.2 12.2 1.9 7.2 13.0 11.0 0.0 2.9 42.8 1.0 0.0 0.6 1.5 0.4 1.9 12.9 0.0 15.1 0.2 0.2 3.8 9.2 1.5 0.4 70.3 0.1 22.9 5.8 407.1 0.0 0.3 0.0 2.0 1326.9 1240.5 5.4 3.7 871.6 44.4 24.4 1096.6 0.7 60.8 0.5 0.1 0.1 1.1 1.2 4.7 1.0 0.0 3.8 11.0 0.2 26.3 2.2 2.8 2.4 4.6 0.4 28.3 5.3 43.6 0.0 0.4 0.3 LY6D E48 ENSG00000167656 "Lymphocyte antigen 6 family member D" Q14210 8 142784882-142786539 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 2074.3;skin 1: 850.4;vagina: 491.2" "Group enriched" "Detected in many" 9 "Basal keratinocytes: 1171.6;Squamous epithelial cells: 1913.0;Suprabasal keratinocytes: 3866.1" "Group enriched" "Detected in many" 7 "cervical cancer: 409.8;head and neck cancer: 444.6;urothelial cancer: 242.3" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 14 "A-431: 162.0" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA024755, HPA064317" Enhanced NA NA 210000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA024755: AB_1853410, HPA064317: AB_2685244" "unprognostic (2.13e-2)" "unprognostic (7.48e-2)" "unprognostic (2.00e-1)" "unprognostic (1.08e-2)" "unprognostic (8.97e-2)" "unprognostic (1.51e-2)" "unprognostic (3.84e-1)" "unprognostic (5.11e-2)" "prognostic unfavorable (1.94e-6)" "unprognostic (8.68e-2)" "prognostic unfavorable (1.20e-4)" "unprognostic (2.50e-1)" "unprognostic (3.97e-1)" "unprognostic (5.40e-4)" "unprognostic (1.06e-1)" 1.7 47.6 0.6 0.2 0.6 0.0 20.4 0.5 1.4 297.4 0.5 0.9 0.0 0.3 0.0 2074.3 1.0 1.4 0.8 0.6 0.5 0.3 0.8 0.5 0.0 0.5 0.5 0.5 1.0 0.0 1.0 2.5 0.5 15.3 0.2 0.0 235.4 0.3 2.6 850.4 0.5 0.0 0.5 0.5 12.4 0.4 0.5 4.6 0.4 0.0 75.6 65.2 491.2 0.7 162.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.1 6.0 0.0 1.3 0.0 0.2 0.0 0.0 4.0 11.9 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.9 0.0 0.0 1.2 4.0 0.2 0.0 0.0 0.8 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.5 1.4 0.6 0.5 0.5 0.5 0.5 0.5 0.5 0.7 0.1 3.2 0.0 0.0 0.0 1171.6 9.4 244.9 138.3 0.0 14.8 14.1 0.2 0.0 154.0 1.8 0.0 0.9 0.1 0.4 1.9 1.1 0.0 0.4 0.1 10.7 0.0 0.0 0.3 0.2 5.7 9.8 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 22.4 0.0 137.3 0.0 0.0 0.8 163.7 0.0 0.0 0.0 0.0 0.0 0.1 7.0 0.0 0.0 2.5 18.9 0.0 1.2 12.2 0.0 0.0 0.6 16.1 0.0 0.0 1913.0 3866.1 8.2 4.0 0.0 0.4 164.6 LYPD5 FLJ30469 ENSG00000159871 "LY6/PLAUR domain containing 5" Q6UWN5 19 43785874-43827206 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "skin 1: 50.6" "Cell type enhanced" "Detected in many" "Early spermatids: 33.0;Late spermatids: 81.8;Melanocytes: 17.8;Syncytiotrophoblasts: 21.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 8.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 3.5;BEWO: 5.0;HaCaT: 5.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA042511, HPA054670" Approved Approved Nucleoplasm,Cytosol No NA "Cluster 7: Monocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA042511: AB_10794279, HPA054670: AB_2682567" "unprognostic (4.27e-3)" "prognostic favorable (5.84e-4)" "unprognostic (4.63e-2)" "unprognostic (8.42e-3)" "unprognostic (4.80e-2)" "unprognostic (2.91e-3)" "unprognostic (3.96e-1)" "unprognostic (7.93e-3)" "unprognostic (1.37e-1)" "unprognostic (1.18e-1)" "unprognostic (1.40e-3)" "unprognostic (1.19e-1)" "unprognostic (1.83e-3)" "unprognostic (8.30e-2)" "unprognostic (2.02e-1)" "unprognostic (7.53e-3)" "unprognostic (4.08e-2)" 1.1 0.6 2.6 1.4 2.5 0.1 2.9 1.8 6.0 9.3 0.0 2.3 0.1 0.9 1.4 11.4 0.8 1.1 1.5 3.0 2.9 3.0 0.4 4.0 0.7 6.8 3.2 0.4 0.3 0.6 1.6 1.0 6.6 1.3 0.8 2.0 3.1 0.8 0.2 50.6 1.2 1.1 1.7 4.8 1.0 3.8 4.1 0.9 1.4 0.4 1.7 1.9 9.0 4.1 3.5 0.0 0.2 0.0 0.0 0.0 5.0 0.0 0.0 0.5 0.6 0.4 1.2 0.2 0.7 0.4 1.4 5.2 0.0 0.7 0.3 0.6 0.0 0.1 0.4 0.0 1.5 0.1 0.0 1.7 1.5 0.2 0.7 0.0 0.2 0.1 0.1 0.1 0.0 0.2 0.1 0.0 0.3 1.9 1.2 0.0 0.0 0.0 0.3 0.6 0.2 0.1 0.7 0.7 0.0 1.1 0.4 0.1 0.3 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.3 0.0 0.0 0.1 2.6 2.5 1.8 6.0 3.0 2.9 6.8 3.2 6.6 1.7 4.1 4.1 0.5 0.0 0.0 4.6 0.0 3.6 2.6 1.6 4.0 1.4 1.8 1.5 0.7 0.0 0.4 0.0 0.0 1.6 0.1 3.7 3.9 0.6 33.0 0.2 0.1 3.1 0.0 0.0 7.7 0.9 8.4 1.2 0.0 0.2 0.0 0.5 0.7 0.0 2.4 0.0 8.8 1.9 0.0 0.6 0.8 81.8 0.3 0.5 17.8 1.0 0.0 0.9 0.0 9.5 7.8 0.3 2.3 1.2 0.0 1.4 0.2 0.0 1.4 0.9 0.0 1.0 0.2 9.9 2.6 3.7 2.8 21.6 0.1 0.1 0.8 6.2 LYPD6B "CT116, LYPD7" ENSG00000150556 "LY6/PLAUR domain containing 6B" Q8NI32 2 149038107-149215262 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 95.5" "Cell type enhanced" "Detected in many" "Early spermatids: 245.7;Gastric mucus-secreting cells: 87.7;Inhibitory neurons: 77.8;Late spermatids: 118.5;Suprabasal keratinocytes: 69.0" "Cancer enhanced" "Detected in many" "ovarian cancer: 17.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "basophil: 13.8" "Lineage enriched" "Detected in many" 4 "granulocytes: 13.8" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 64.8;LHCN-M2: 102.3;NB-4: 34.7;RT4: 54.7;SK-BR-3: 32.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA049239 Uncertain "Intracellular and membrane" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 31: Skin - Epidermis development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 34: Spermatids - Unknown function" "HPA049239: AB_2680688" "unprognostic (2.42e-2)" "unprognostic (1.65e-1)" "unprognostic (8.42e-2)" "unprognostic (3.12e-3)" "unprognostic (1.64e-1)" "unprognostic (3.37e-1)" "unprognostic (2.01e-2)" "unprognostic (6.27e-2)" "unprognostic (3.64e-2)" "unprognostic (7.95e-3)" "unprognostic (2.59e-2)" "unprognostic (4.40e-2)" "unprognostic (1.77e-2)" "unprognostic (1.45e-1)" "unprognostic (2.85e-1)" "unprognostic (2.68e-1)" "unprognostic (1.32e-3)" 0.3 0.2 3.5 0.4 2.5 0.2 16.4 1.6 5.3 2.8 1.6 1.7 2.6 0.9 1.2 4.1 23.4 37.3 0.0 4.3 4.1 20.5 0.9 1.7 0.4 2.3 7.3 0.4 12.3 16.1 0.4 0.8 3.0 11.1 3.3 1.0 5.8 15.2 0.2 95.5 1.2 0.3 1.9 2.8 41.3 34.1 8.0 0.3 0.2 0.0 1.9 14.2 6.3 2.1 1.4 0.0 0.0 1.5 0.0 0.1 0.1 8.0 1.5 6.6 2.5 1.0 0.0 0.0 0.0 64.8 0.0 14.0 1.5 1.3 20.6 0.0 7.4 0.0 1.9 0.0 0.2 0.0 0.1 0.6 21.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 102.3 24.3 0.0 34.7 2.0 14.6 0.3 0.0 0.4 4.3 3.2 54.7 3.9 0.1 0.4 32.1 0.0 6.3 4.8 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.8 13.8 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.5 2.5 1.6 5.3 4.3 4.1 2.3 7.3 3.0 1.9 8.0 2.1 0.5 0.0 2.0 2.3 5.5 29.8 21.0 30.6 6.2 0.0 23.4 17.1 1.4 42.9 23.9 46.0 0.0 0.1 0.1 4.0 7.9 12.4 245.7 5.2 0.3 1.0 2.4 2.7 4.6 19.1 0.7 0.8 87.7 5.7 0.0 0.4 0.0 0.1 0.1 0.0 77.8 3.9 8.2 0.0 2.8 118.5 2.1 0.4 5.4 0.0 0.6 0.0 0.0 0.0 0.4 30.9 6.0 0.0 4.5 40.6 5.7 0.2 21.4 0.0 0.0 0.0 1.3 4.2 1.7 3.5 69.0 0.3 1.1 0.0 3.5 53.7 MAB21L4 "C2orf54, FLJ22671" ENSG00000172478 "Mab-21 like 4" Q08AI8 2 240886048-240896889 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 262.6;vagina: 80.4" "Cell type enriched" "Detected in single" 7 "Cytotrophoblasts: 2.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "CACO-2: 45.9;HaCaT: 34.3;SK-BR-3: 117.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA052722 Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Golgi apparatus" "HPA052722: " "unprognostic (5.86e-3)" "unprognostic (4.17e-2)" "unprognostic (1.73e-1)" "prognostic unfavorable (2.77e-4)" "unprognostic (1.43e-2)" "unprognostic (1.33e-1)" "unprognostic (8.95e-2)" "unprognostic (1.70e-1)" "unprognostic (1.89e-2)" "unprognostic (2.83e-2)" "unprognostic (2.96e-1)" "unprognostic (2.08e-1)" "unprognostic (6.46e-2)" "unprognostic (1.55e-1)" "unprognostic (8.26e-2)" "unprognostic (2.05e-1)" 0.2 0.1 0.3 1.0 0.5 0.0 1.8 0.5 1.3 36.0 0.0 2.9 11.5 0.2 0.1 262.6 0.9 0.5 0.1 0.8 0.0 13.3 13.0 10.0 0.3 0.3 0.0 0.1 1.2 0.0 0.2 0.8 0.5 1.5 2.5 0.3 29.2 0.2 0.3 60.8 4.9 0.1 0.0 0.2 5.8 0.2 0.2 1.1 0.1 0.0 23.5 2.0 80.4 0.1 0.5 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 45.9 2.7 0.3 0.3 0.0 0.0 34.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 6.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.3 0.0 5.7 0.1 0.1 0.2 7.3 0.0 0.1 0.0 11.4 0.3 5.9 2.3 0.0 0.0 117.0 0.0 0.2 0.9 0.7 0.0 0.0 1.2 0.1 0.0 0.6 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.3 0.5 0.5 1.3 0.8 0.0 0.3 0.0 0.5 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 MAL2 ENSG00000147676 "Mal, T cell differentiation protein 2" Q969L2 8 119165034-119245673 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 259.2" "Cell type enhanced" "Detected in many" "Collecting duct cells: 389.9;Distal enterocytes: 433.3;Pancreatic endocrine cells: 329.8;Suprabasal keratinocytes: 455.8;Urothelial cells: 594.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 1042.5;HaCaT: 451.8;OE19: 1132.4;RPTEC TERT1: 385.4;SK-BR-3: 1439.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043831 Uncertain NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "HPA043831: " "prognostic unfavorable (4.57e-6)" "unprognostic (3.12e-1)" "unprognostic (4.04e-1)" "prognostic unfavorable (8.44e-5)" "unprognostic (2.10e-2)" "unprognostic (1.83e-2)" "unprognostic (1.03e-2)" "unprognostic (7.20e-2)" "unprognostic (5.86e-2)" "unprognostic (2.00e-3)" "prognostic unfavorable (3.98e-4)" "unprognostic (1.09e-1)" "prognostic favorable (2.39e-5)" "unprognostic (5.48e-2)" "unprognostic (1.34e-1)" "unprognostic (3.33e-1)" "unprognostic (9.27e-3)" 14.1 1.8 8.5 10.6 13.4 0.0 65.6 15.3 28.0 41.9 0.0 102.9 64.3 6.7 14.2 259.2 54.4 33.1 2.1 22.2 17.0 85.7 47.0 81.6 1.3 0.0 4.2 0.5 37.4 43.5 35.8 12.0 0.0 26.9 94.2 2.6 62.6 41.2 0.4 121.0 53.0 2.6 0.0 0.4 137.6 12.5 8.3 4.3 147.5 0.1 56.0 69.0 102.6 3.4 1042.5 0.0 1.0 0.3 0.2 0.0 92.9 0.1 2.3 1.2 1.6 87.7 329.0 0.3 56.2 0.0 0.4 451.8 0.8 32.9 0.5 0.9 2.6 0.0 13.8 86.1 0.3 0.6 0.3 0.0 225.5 0.0 34.3 1.7 0.3 0.0 0.2 0.5 0.0 244.9 0.8 0.3 8.2 1132.4 309.2 0.6 0.0 0.7 385.4 257.4 56.7 0.3 17.8 1439.4 2.7 6.8 191.4 3.0 0.0 0.6 3.1 1.3 1.9 5.5 0.8 1.0 0.4 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.5 13.4 15.3 28.0 22.2 17.0 0.0 4.2 0.0 0.0 8.3 3.4 0.5 112.2 130.8 4.2 2.7 114.7 79.9 59.3 19.9 1.5 118.9 50.7 1.6 90.1 119.7 389.9 0.0 25.0 0.4 433.3 109.5 206.0 0.5 71.8 10.3 3.7 41.9 0.0 62.4 178.6 23.5 4.7 149.9 139.4 14.7 0.0 3.6 44.9 2.9 5.0 9.8 145.9 71.2 0.3 14.3 2.2 0.6 2.3 16.0 3.7 3.6 1.0 0.0 3.5 3.6 329.8 252.9 0.0 1.2 285.4 70.2 19.9 107.5 1.0 0.0 0.0 7.0 1.9 9.7 268.8 455.8 9.3 2.8 0.0 122.5 594.5 MAP1LC3A "ATG8E, LC3, LC3A, MAP1ALC3, MAP1BLC3" ENSG00000101460 "Microtubule associated protein 1 light chain 3 alpha" Q9H492 20 34546854-34560345 "Predicted intracellular proteins" "Autophagy, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 674.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 7 "neutrophil: 85.4" "Lineage enriched" "Detected in all" 7 "granulocytes: 85.4" "Cell line enhanced" "Detected in many" "HHSteC: 57.5;HSkMC: 71.2;SK-BR-3: 62.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007649, CAB037174, HPA042824, HPA052474, HPA052484" Enhanced Approved Vesicles NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "CAB037174: AB_1079382, HPA007649: AB_1853943, HPA042824: , HPA052474: AB_2681844, HPA052484: AB_2681846" "unprognostic (6.10e-3)" "unprognostic (8.03e-2)" "unprognostic (1.02e-1)" "unprognostic (1.99e-2)" "unprognostic (4.56e-3)" "unprognostic (1.06e-2)" "unprognostic (1.55e-1)" "unprognostic (1.79e-1)" "unprognostic (4.78e-2)" "unprognostic (1.98e-1)" "prognostic favorable (5.31e-5)" "unprognostic (2.82e-2)" "unprognostic (1.59e-3)" "unprognostic (3.84e-1)" "unprognostic (1.35e-1)" "unprognostic (7.90e-2)" "unprognostic (2.76e-1)" 53.0 26.6 120.8 13.7 122.1 16.4 40.6 114.4 177.2 49.6 69.7 56.3 30.6 44.9 17.8 22.6 41.7 23.9 81.7 123.7 148.4 54.2 53.2 39.4 28.1 137.1 135.6 38.3 24.8 23.7 84.8 12.4 155.9 46.6 19.7 31.6 31.0 20.3 54.7 64.8 44.9 19.1 101.2 22.0 36.6 52.8 116.2 6.9 52.9 34.1 30.4 39.1 43.5 123.3 0.0 7.0 4.2 0.0 28.4 37.3 0.2 26.1 21.9 16.3 14.9 0.1 0.5 0.0 0.3 21.3 39.5 4.8 0.1 8.1 3.2 6.2 2.0 0.1 17.2 0.0 57.5 0.0 14.0 71.2 1.4 11.4 4.9 0.1 13.5 0.0 0.0 0.1 17.4 0.0 0.2 0.5 1.6 5.3 5.2 0.0 0.0 0.0 0.0 0.0 41.4 31.9 29.6 62.2 0.0 16.3 0.3 22.7 20.5 45.2 0.4 9.8 11.2 0.0 6.5 0.0 29.4 0.0 16.1 4.0 3.2 11.0 5.1 4.8 3.7 9.4 5.5 5.4 1.0 6.0 1.7 3.4 85.4 3.3 1.7 4.5 12.1 2.9 120.8 122.1 114.4 177.2 123.7 148.4 137.1 135.6 155.9 101.2 116.2 123.3 107.4 0.0 6.6 19.2 18.3 57.7 123.0 50.5 12.5 127.2 41.9 57.8 25.4 41.5 27.1 46.0 85.5 25.7 26.1 67.3 113.5 42.0 137.3 98.4 78.4 64.4 165.1 3.6 48.4 23.5 15.8 75.4 34.1 90.6 18.4 90.8 75.7 44.6 37.9 70.7 58.8 70.5 136.3 16.1 47.1 674.0 95.1 17.5 62.2 14.0 21.0 98.7 7.2 12.5 54.6 44.7 82.5 108.7 10.1 146.3 149.4 120.0 40.7 127.7 138.1 77.7 119.3 53.0 21.6 5.8 51.4 211.8 26.4 79.8 76.7 98.1 MAP3K9 "MEKK9, MLK1, PRKE1" ENSG00000006432 "Mitogen-activated protein kinase kinase kinase 9" P80192 14 70722526-70809534 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 22.7;retina: 9.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 49.6;Inhibitory neurons: 58.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 22.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000942 Approved Approved Nucleoplasm,Nucleoli "Intracellular and membrane" NA NA "Cluster 6: Brain - Smell perception" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Nucleoli" "HPA000942: AB_1079360" "unprognostic (1.20e-1)" "unprognostic (3.75e-1)" "unprognostic (4.01e-2)" "unprognostic (1.43e-2)" "unprognostic (3.16e-3)" "unprognostic (2.45e-2)" "unprognostic (3.75e-5)" "unprognostic (2.58e-1)" "unprognostic (4.20e-2)" "unprognostic (4.38e-2)" "unprognostic (1.53e-2)" "unprognostic (2.48e-2)" "unprognostic (4.23e-6)" "unprognostic (5.71e-3)" "unprognostic (6.86e-3)" "unprognostic (1.79e-1)" "unprognostic (2.35e-1)" 0.2 1.0 3.3 1.0 4.6 0.7 1.3 10.7 22.7 0.9 0.4 1.5 1.5 0.4 1.5 5.1 1.0 0.4 0.5 4.0 3.2 1.4 0.7 1.9 1.4 8.6 3.0 0.6 2.2 2.7 1.1 0.6 7.7 0.9 1.5 9.6 1.7 0.5 0.8 4.0 1.4 0.2 0.3 0.9 1.6 5.5 10.0 0.9 2.7 0.4 3.6 0.7 1.8 6.8 22.3 10.5 2.0 2.5 0.0 0.0 6.7 0.5 0.3 2.1 1.9 7.8 8.6 4.5 2.8 0.1 4.7 10.3 6.5 12.8 2.2 3.0 1.7 0.2 4.1 5.2 0.3 0.5 0.9 0.1 6.5 1.5 12.7 3.7 0.0 4.1 1.7 1.0 0.5 9.4 3.7 0.5 4.2 9.0 4.5 1.3 3.9 0.9 4.6 10.9 13.8 3.0 6.3 7.7 1.2 3.7 6.9 0.8 0.0 0.0 8.5 0.0 3.5 2.2 5.6 2.4 3.4 0.4 1.4 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.1 0.1 0.2 0.2 0.0 0.0 0.2 0.0 3.3 4.6 10.7 22.7 4.0 3.2 8.6 3.0 7.7 0.3 10.0 6.8 0.3 6.4 13.4 6.8 3.9 8.7 13.7 9.4 6.8 17.7 11.2 4.8 2.3 14.3 12.4 7.3 12.5 2.8 1.7 5.7 1.9 6.1 19.8 7.4 0.7 0.8 8.4 0.0 49.6 4.8 1.6 1.0 4.1 8.5 1.3 1.8 1.1 4.8 1.2 30.3 58.1 4.0 4.1 0.8 1.9 20.0 0.6 0.8 3.6 5.6 0.4 3.2 0.0 8.5 1.3 11.1 3.9 0.0 2.8 15.8 2.6 2.8 7.1 12.7 0.0 0.8 1.3 8.0 8.4 12.6 9.1 4.0 3.7 6.0 5.8 27.9 MC5R ENSG00000176136 "Melanocortin 5 receptor" P33032 18 13824149-13827323 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 2.4;lymphoid tissue: 1.0" "Cell type enriched" "Detected in single" 17 "Squamous epithelial cells: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-138 MG: 1.8" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA042365, HPA058088" Approved Supported "Plasma membrane" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane" "HPA042365: AB_2677961, HPA058088: " "unprognostic (1.57e-2)" "unprognostic (1.37e-1)" "unprognostic (8.77e-2)" "unprognostic (7.10e-2)" "unprognostic (2.64e-2)" "unprognostic (1.30e-2)" "unprognostic (9.04e-3)" "unprognostic (1.54e-1)" 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 2.4 0.5 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.3 1.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.4 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.2 0.1 0.3 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 MECOM "EVI1, KMT8E, MDS1, MDS1-EVI1, PRDM3" ENSG00000085276 "MDS1 and EVI1 complex locus" Q03112 3 169083499-169663775 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Apoptosis, Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Methyltransferase, Transferase" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 73.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 184.8;Collecting duct cells: 125.0;Gastric mucus-secreting cells: 111.1;Glandular and luminal cells: 107.7;Microglial cells: 346.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 55.5;RPTEC TERT1: 71.2;RT4: 119.6;TIME: 53.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046537 Supported Supported "Nuclear speckles" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 46: Fibroblasts - ECM organization" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" "Nuclear speckles" "HPA046537: AB_2679689" "unprognostic (4.09e-2)" "unprognostic (1.96e-1)" "unprognostic (3.24e-3)" "unprognostic (7.29e-2)" "unprognostic (2.87e-2)" "unprognostic (2.53e-1)" "unprognostic (1.83e-2)" "unprognostic (4.77e-3)" "unprognostic (1.53e-2)" "unprognostic (3.27e-3)" "prognostic unfavorable (2.59e-4)" "unprognostic (1.87e-1)" "unprognostic (2.60e-3)" "unprognostic (6.54e-2)" "unprognostic (1.03e-1)" "unprognostic (2.81e-2)" "unprognostic (3.37e-3)" 16.0 0.9 7.3 7.3 7.2 1.4 12.3 8.5 7.3 21.3 2.4 24.9 19.8 17.3 4.4 13.5 23.4 8.3 13.0 4.9 6.3 41.3 1.4 25.5 1.5 9.1 7.2 2.3 23.3 1.7 4.2 17.4 8.9 6.9 30.0 1.8 8.8 8.0 4.3 2.6 10.2 8.0 4.1 6.2 73.3 3.0 8.1 2.0 5.7 12.0 5.3 30.4 7.5 6.3 25.8 0.7 0.9 0.2 3.7 2.7 1.1 3.7 4.2 1.1 2.2 10.7 26.1 0.9 39.1 0.6 5.5 13.4 10.2 15.7 3.1 1.4 16.6 16.7 7.6 1.1 0.4 0.3 5.1 5.7 2.2 1.0 12.1 12.0 55.5 1.4 13.0 1.8 10.3 9.8 0.9 0.4 1.7 13.5 6.6 9.8 13.1 0.3 71.2 119.6 1.0 3.1 1.3 6.7 0.3 1.5 7.1 1.1 53.4 9.7 6.6 2.5 16.9 1.4 0.7 0.9 4.8 1.0 1.6 0.9 0.4 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.5 0.2 0.0 0.0 0.3 0.4 0.5 1.6 0.1 0.0 7.3 7.2 8.5 7.3 4.9 6.3 9.1 7.2 8.9 4.1 8.1 6.3 80.2 60.9 184.8 16.0 0.6 2.2 33.3 29.4 10.2 0.0 1.2 0.9 11.4 2.8 69.6 125.0 0.0 1.1 0.1 25.5 52.8 1.6 10.4 71.9 5.8 70.5 19.9 7.4 10.3 75.4 0.2 4.8 111.1 107.7 9.5 0.8 69.3 0.2 0.0 0.0 9.1 29.0 20.3 0.6 1.9 3.2 0.3 2.6 1.8 346.6 1.0 0.0 0.0 6.0 13.8 49.8 19.3 0.0 0.3 13.9 6.2 0.7 53.2 0.1 0.0 1.4 5.7 3.0 1.2 39.4 1.4 0.4 1.3 0.5 53.9 45.4 MELK KIAA0175 ENSG00000165304 "Maternal embryonic leucine zipper kinase" Q14680 9 36572862-36677683 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 10.0;lymphoid tissue: 21.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 16.1;Erythroid cells: 15.2;Extravillous trophoblasts: 44.1;Spermatocytes: 23.2;Spermatogonia: 21.3" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 4 "T-reg: 1.7" "Lineage enriched" "Detected in single" 4 "T-cells: 1.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA017214 Uncertain NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 12: Non-specific - Cell cycle regulation" "HPA017214: AB_1853798" "unprognostic (5.03e-2)" "unprognostic (9.57e-2)" "unprognostic (2.27e-2)" "unprognostic (3.42e-3)" "unprognostic (2.16e-1)" "unprognostic (1.23e-1)" "prognostic unfavorable (2.91e-7)" "prognostic unfavorable (3.99e-4)" "unprognostic (1.26e-2)" "unprognostic (1.60e-2)" "prognostic unfavorable (4.58e-4)" "unprognostic (4.69e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (8.86e-3)" "unprognostic (1.37e-1)" "unprognostic (2.40e-1)" "unprognostic (1.35e-1)" 0.9 0.5 0.0 5.7 0.0 10.0 1.4 0.0 0.1 1.3 0.0 6.8 5.2 1.0 0.0 7.9 0.3 0.6 0.2 0.0 0.0 0.3 0.7 0.9 10.0 0.0 0.1 0.2 0.3 0.1 0.0 5.3 0.1 0.3 8.5 0.0 1.2 0.1 0.0 3.4 4.4 2.4 0.0 2.0 3.2 9.2 0.3 21.0 0.3 0.1 11.7 1.7 2.3 0.0 123.4 62.1 81.6 48.5 11.1 18.8 47.1 88.8 62.2 121.5 148.2 47.8 47.3 40.9 27.8 43.8 106.5 41.0 71.7 55.5 133.1 112.3 28.6 32.0 69.1 48.1 4.3 50.2 39.0 6.9 9.8 93.9 53.0 15.6 62.2 61.9 41.7 63.2 100.9 40.9 63.1 23.4 65.1 55.1 47.9 57.4 54.9 25.8 37.7 40.7 55.1 40.8 47.4 45.3 28.6 45.2 38.0 23.7 30.8 65.4 81.8 56.1 82.3 12.3 47.9 60.7 41.2 36.8 91.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 1.7 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.7 1.9 4.6 0.9 3.5 0.0 0.0 0.9 0.8 0.4 0.0 2.0 0.0 0.0 16.1 0.7 4.5 0.0 1.1 2.8 2.9 1.4 1.3 0.0 15.2 0.8 1.1 44.1 3.3 4.6 2.1 0.0 7.8 1.4 0.7 10.1 0.0 0.7 4.7 4.1 1.6 3.0 2.7 1.2 1.9 0.0 0.0 3.1 0.0 2.1 1.0 0.4 1.7 2.7 0.0 10.2 0.5 0.6 0.1 2.0 0.0 0.0 0.0 3.7 23.2 21.3 9.3 1.7 8.9 2.7 0.7 8.9 2.3 MELTF "CD228, FLJ38863, MAP97, MFI2, MGC4856, MTf, MTF1" ENSG00000163975 Melanotransferrin P08582 3 196988621-197029817 "CD markers, Plasma proteins, Predicted intracellular proteins" "Ion transport, Iron transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 35.1;salivary gland: 68.7" "Cell type enhanced" "Detected in some" "Breast glandular cells: 21.1;Breast myoepithelial cells: 20.6;Collecting duct cells: 14.7;Ductal cells: 28.3;Hofbauer cells: 15.4;Pancreatic endocrine cells: 66.4" "Cancer enhanced" "Detected in all" "melanoma: 32.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 162.1;SK-MEL-30: 201.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA004880 Approved "Intracellular and membrane" NA NA 41000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA004880: AB_1853844" "unprognostic (8.68e-3)" "unprognostic (3.68e-2)" "unprognostic (1.75e-2)" "unprognostic (7.68e-3)" "unprognostic (1.06e-2)" "unprognostic (1.08e-2)" "unprognostic (5.53e-2)" "unprognostic (1.64e-3)" "unprognostic (1.20e-2)" "unprognostic (1.23e-1)" "unprognostic (3.68e-3)" "unprognostic (8.14e-2)" "prognostic unfavorable (6.99e-11)" "unprognostic (2.29e-1)" "unprognostic (2.11e-1)" "unprognostic (5.75e-2)" "unprognostic (2.09e-2)" 10.0 1.7 2.3 3.8 1.7 2.3 7.4 2.1 3.8 8.1 27.2 4.0 2.4 6.8 0.7 2.9 8.6 1.6 7.5 2.5 1.9 35.1 1.6 1.9 1.9 0.6 2.8 1.2 4.6 10.3 2.9 1.5 0.4 4.1 2.1 0.3 68.7 5.5 1.1 16.4 9.9 1.2 0.5 1.1 1.7 3.4 6.5 2.9 3.1 1.0 1.6 3.2 7.3 2.0 162.1 34.6 0.4 1.2 4.8 6.0 4.0 2.8 1.5 5.2 6.3 9.8 23.6 4.5 33.3 5.6 4.5 49.6 1.8 0.1 2.3 7.4 10.8 5.6 7.9 4.1 30.5 0.8 30.8 33.0 4.3 4.3 0.4 0.2 0.8 8.9 4.3 30.5 3.1 9.8 9.3 0.0 3.6 6.9 22.5 13.4 5.3 2.0 0.8 1.5 3.1 11.3 32.5 2.8 201.4 3.8 9.5 4.8 1.2 1.2 26.8 5.5 19.9 5.3 46.0 4.5 3.9 9.5 0.2 0.0 0.1 0.0 0.2 0.2 0.8 0.0 0.2 0.2 0.5 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.2 2.3 1.7 2.1 3.8 2.5 1.9 0.6 2.8 0.4 0.5 6.5 2.0 0.8 0.0 1.7 0.0 1.0 0.0 0.0 0.0 0.0 0.0 21.1 20.6 0.0 0.0 1.8 14.7 0.0 0.2 1.0 0.0 0.0 28.3 0.0 3.2 6.1 0.6 0.0 0.0 0.0 5.7 0.3 3.7 0.0 4.4 0.0 3.0 0.0 0.0 15.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 2.6 0.0 0.0 0.0 0.0 66.4 0.0 0.0 1.7 0.0 0.0 0.5 1.5 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.5 0.5 0.1 0.0 0.0 METTL7B "ALDI, MGC17301" ENSG00000170439 "Methyltransferase like 7B" Q6UX53 12 55681678-55684611 "Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 133.1;heart muscle: 124.2;liver: 284.3" "Cell type enhanced" "Detected in some" "Hepatocytes: 83.9;Hofbauer cells: 72.7;Proximal enterocytes: 192.4;Proximal tubular cells: 55.6" "Cancer enhanced" "Detected in many" "glioma: 97.9;liver cancer: 97.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "intermediate monocyte: 4.5;myeloid DC: 7.0;naive B-cell: 1.7;non-classical monocyte: 3.3" "Group enriched" "Detected in many" 45 "B-cells: 1.7;dendritic cells: 7.0;monocytes: 4.5" "Cell line enhanced" "Detected in many" "CACO-2: 28.4;CAPAN-2: 56.6;EFO-21: 41.3;Hep G2: 28.7;LHCN-M2: 47.0;OE19: 32.5;THP-1: 42.2;U-87 MG: 41.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA038644 Enhanced Approved Vesicles,Microtubules NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 45: Enterocytes - Digestion" Microtubules Vesicles "HPA038644: AB_2676130" "unprognostic (7.54e-2)" "unprognostic (7.15e-2)" "unprognostic (5.55e-2)" "unprognostic (3.07e-3)" "unprognostic (6.30e-2)" "prognostic unfavorable (2.85e-4)" "unprognostic (2.00e-1)" "unprognostic (2.22e-1)" "unprognostic (1.22e-1)" "unprognostic (2.55e-1)" "unprognostic (2.98e-2)" "unprognostic (5.33e-2)" "unprognostic (2.64e-1)" "unprognostic (2.76e-2)" "unprognostic (7.10e-2)" "prognostic favorable (2.37e-4)" "unprognostic (2.43e-1)" 2.1 1.7 5.5 1.8 5.9 1.2 0.9 4.9 10.8 0.4 5.9 28.5 59.6 0.4 133.1 0.1 3.1 11.7 124.2 13.1 5.9 52.1 284.3 1.6 2.3 8.4 5.5 0.1 2.9 0.2 3.1 10.9 5.0 0.3 23.6 1.3 0.5 0.8 7.4 0.9 55.3 2.1 5.7 4.3 4.2 0.7 11.6 0.2 3.3 10.0 0.5 1.3 0.1 7.7 0.4 21.8 0.1 0.5 4.3 15.3 0.3 0.8 3.2 0.2 1.4 28.4 56.6 11.6 41.3 1.2 1.1 0.1 4.1 0.3 0.8 0.0 5.4 1.2 3.2 28.7 0.0 0.6 0.0 4.0 0.0 1.0 0.0 4.2 0.0 0.0 0.2 0.0 47.0 20.2 0.0 0.4 5.7 32.5 2.7 0.0 1.5 2.7 0.5 0.1 0.1 0.3 2.2 0.0 3.9 0.2 3.8 42.2 0.0 3.1 3.5 0.4 2.9 0.0 0.6 3.5 41.9 9.9 0.2 0.0 0.8 0.0 0.0 4.5 0.0 0.5 0.0 0.0 7.0 1.7 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.4 5.5 5.9 4.9 10.8 13.1 5.9 8.4 5.5 5.0 5.7 11.6 7.7 0.0 0.0 1.5 0.7 0.5 0.0 0.3 0.0 0.0 0.0 0.1 0.1 26.5 22.8 0.6 0.0 0.0 0.5 0.0 29.0 3.9 3.9 0.0 0.1 0.0 0.5 1.2 4.0 0.7 5.1 0.5 2.0 2.6 0.2 0.0 0.8 1.1 83.9 72.7 0.0 0.1 14.0 0.0 17.0 0.0 0.0 0.0 3.3 0.0 0.0 0.2 0.5 0.0 0.0 0.0 4.6 20.7 1.2 0.0 0.1 192.4 55.6 0.0 0.0 0.0 7.8 0.6 0.0 0.1 0.0 0.0 0.7 0.3 0.1 22.2 0.1 MKI67 "MIB-1, PPP1R105" ENSG00000148773 "Marker of proliferation Ki-67" P46013 10 128096659-128126423 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 46.3;lymphoid tissue: 52.7" "Cell type enhanced" "Detected in many" "Erythroid cells: 232.9;Extravillous trophoblasts: 86.1;Granulosa cells: 87.0;Plasma cells: 107.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "CAB000058, HPA000451, HPA001164, CAB068198" Enhanced Enhanced "Nucleoplasm,Nucleoli rim,Mitotic chromosome" Yes Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nucleoli rim" "Mitotic chromosome" "CAB000058: AB_2142367, CAB068198: AB_2665702, HPA000451: AB_1079186, HPA001164: AB_1079187" "unprognostic (2.54e-1)" "unprognostic (1.29e-1)" "unprognostic (3.37e-1)" "unprognostic (9.92e-3)" "unprognostic (3.17e-1)" "unprognostic (1.10e-1)" "prognostic unfavorable (3.61e-6)" "unprognostic (7.16e-3)" "unprognostic (1.45e-2)" "unprognostic (3.73e-1)" "prognostic unfavorable (9.47e-5)" "unprognostic (2.45e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.42e-2)" "unprognostic (2.10e-1)" "unprognostic (2.50e-1)" "unprognostic (4.61e-1)" 0.9 0.7 0.0 8.5 0.1 46.3 1.7 0.0 0.1 1.2 0.2 8.1 6.2 1.0 0.0 10.0 0.3 0.9 0.3 0.1 0.1 0.4 0.8 1.4 14.9 0.1 1.0 0.2 0.2 0.1 0.1 4.1 0.6 0.4 9.2 0.0 1.4 0.1 0.0 6.6 5.8 2.6 0.0 4.8 4.2 2.3 0.9 52.7 0.4 0.1 16.4 1.8 2.8 0.3 204.6 101.5 103.2 73.6 4.3 8.7 32.1 75.7 55.3 70.3 62.3 83.9 82.3 152.6 21.3 51.9 46.4 120.7 109.3 56.8 104.7 161.8 53.1 131.0 79.4 52.7 0.1 186.0 68.0 2.0 2.5 72.2 73.2 17.2 69.8 69.5 61.2 142.1 70.5 80.9 111.7 56.6 41.3 52.7 45.7 82.2 135.1 20.3 25.6 56.2 35.9 38.9 107.1 38.0 17.3 33.9 31.4 39.3 65.0 37.0 73.6 53.0 206.8 64.2 54.9 177.2 30.7 83.3 32.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 1.0 0.6 0.0 0.9 0.3 0.6 0.0 5.4 0.0 16.0 6.4 1.6 5.3 0.6 0.0 3.9 3.2 1.6 1.5 5.3 0.0 0.0 30.6 7.4 25.0 0.0 0.8 4.2 2.3 10.2 6.7 6.7 232.9 0.0 0.0 86.1 13.5 34.7 13.2 1.3 87.0 5.7 1.7 42.1 0.0 0.0 22.4 2.0 12.9 13.7 0.9 0.3 16.6 3.6 0.0 0.2 0.0 8.2 0.0 0.0 0.1 3.0 0.4 107.4 4.6 2.6 0.1 1.6 0.0 0.0 0.5 13.6 8.1 24.1 50.4 3.0 7.8 23.0 2.7 47.1 4.8 MLANA MART1 ENSG00000120215 Melan-A Q16655 9 5890889-5910606 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "skin 1: 42.9" "Cell type enriched" "Detected in some" 23 "Melanocytes: 1718.2" "Cancer enriched" "Detected in single" 556 "melanoma: 277.0" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 406 "SK-MEL-30: 703.0" "Not detected" "Not detected" "Not detected" "Not detected" "CAB000057, HPA048662" Enhanced NA NA "Cluster 17: Basophils - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 48: Smooth muscle cells - ECM organization" "CAB000057: AB_442107, HPA048662: AB_2680485" "unprognostic (2.52e-2)" "unprognostic (6.87e-2)" "unprognostic (5.20e-2)" "unprognostic (5.61e-2)" "unprognostic (2.58e-2)" "unprognostic (1.46e-1)" "unprognostic (4.53e-1)" "unprognostic (3.32e-1)" "unprognostic (2.82e-2)" "unprognostic (1.71e-3)" "unprognostic (3.60e-3)" "unprognostic (1.20e-1)" "unprognostic (1.45e-2)" "unprognostic (1.60e-1)" "unprognostic (8.01e-2)" "unprognostic (5.78e-2)" "unprognostic (9.43e-2)" 0.1 0.2 0.3 0.4 0.5 0.7 1.4 2.0 0.6 0.1 5.9 0.1 0.1 0.1 0.0 0.2 0.0 0.2 0.1 0.2 0.1 0.3 0.4 0.1 0.4 0.5 0.3 0.1 0.1 0.0 0.1 0.1 0.5 0.1 0.0 0.3 1.1 0.0 0.3 42.9 0.1 0.0 0.1 0.2 0.2 0.3 0.6 0.1 0.2 0.0 0.0 0.2 0.3 0.8 0.8 0.6 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.8 0.2 0.0 0.2 0.1 0.0 0.0 0.0 1.0 0.2 1.7 1.3 1.0 0.0 0.7 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.9 0.0 0.3 0.1 0.6 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.4 0.4 0.1 0.4 0.1 703.0 0.1 0.1 0.3 0.6 0.2 0.4 0.1 0.7 0.2 0.7 0.3 0.2 0.4 0.1 0.8 0.1 0.1 0.2 0.1 0.1 0.2 0.2 0.1 0.0 0.3 0.1 0.2 0.4 0.2 0.1 0.2 0.1 0.0 0.3 0.5 2.0 0.6 0.2 0.1 0.5 0.3 0.5 0.1 0.6 0.8 0.0 0.0 0.0 0.3 0.0 73.7 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.2 0.9 0.0 0.0 1.3 0.0 0.0 1.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 15.5 0.9 0.0 0.2 1718.2 0.0 0.0 0.0 0.0 1.5 1.8 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.3 14.5 0.0 0.5 0.1 0.0 0.0 MMP28 "EPILYSIN, MM28, MMP-25, MMP-28" ENSG00000271447 "Matrix metallopeptidase 28" Q9H239 17 35756249-35795707 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 47.7;Basal respiratory cells: 56.8;Distal enterocytes: 82.0;Paneth cells: 46.2;Proximal enterocytes: 47.2;Urothelial cells: 43.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "naive CD4 T-cell: 6.3;naive CD8 T-cell: 3.7" "Lineage enriched" "Detected in single" 7 "T-cells: 6.3" "Cell line enhanced" "Detected in some" "CAPAN-2: 13.8;HaCaT: 86.9;hTCEpi: 38.3;OE19: 41.7;RT4: 15.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057288, HPA057890" Approved "Nucleoplasm,Focal adhesion sites" "Secreted to extracellular matrix" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Focal adhesion sites" "HPA057288: , HPA057890: " "unprognostic (7.99e-3)" "unprognostic (3.27e-1)" "unprognostic (2.20e-1)" "unprognostic (1.01e-1)" "unprognostic (7.52e-2)" "unprognostic (1.63e-1)" "unprognostic (6.90e-2)" "unprognostic (1.09e-2)" "unprognostic (1.51e-1)" "unprognostic (1.99e-1)" "prognostic unfavorable (6.28e-6)" "unprognostic (9.37e-2)" "unprognostic (1.31e-1)" "unprognostic (8.87e-2)" "unprognostic (1.74e-1)" "unprognostic (1.76e-2)" "unprognostic (3.27e-3)" 14.7 2.0 18.7 0.5 18.1 0.2 8.3 12.1 18.8 4.1 11.9 17.5 1.8 5.2 2.1 13.5 6.1 1.4 3.8 16.2 15.6 1.9 0.3 14.1 0.2 15.2 17.8 1.1 0.8 0.1 1.3 2.0 12.9 5.0 10.5 3.0 2.5 3.5 1.8 23.7 10.2 4.1 14.4 1.1 8.8 22.3 19.3 0.3 5.9 2.4 3.2 16.3 7.6 13.9 0.2 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 13.8 0.1 1.5 0.0 0.1 86.9 0.0 0.2 0.0 0.0 0.7 0.0 0.2 0.0 4.3 0.0 0.0 1.2 38.3 0.0 3.1 0.7 0.3 0.3 0.0 0.2 0.0 0.3 0.1 0.3 0.0 41.7 0.1 0.8 0.0 0.0 0.0 15.7 0.2 0.7 0.8 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.1 0.6 0.2 1.0 0.0 0.4 6.3 3.7 0.0 0.9 0.2 0.9 0.0 0.4 18.7 18.1 12.1 18.8 16.2 15.6 15.2 17.8 12.9 14.4 19.3 13.9 31.5 28.9 26.5 47.7 0.4 38.5 5.3 56.8 21.1 2.7 1.0 1.5 1.3 7.2 15.2 7.3 0.0 0.0 0.2 82.0 0.0 1.2 6.7 0.1 0.0 16.8 3.6 0.4 2.8 0.4 0.0 4.4 12.2 0.1 0.0 0.0 17.9 0.0 0.1 1.7 4.8 32.9 2.0 0.0 1.8 13.4 1.2 0.5 3.6 10.3 0.4 9.4 1.0 1.0 0.6 16.7 46.2 3.0 0.1 8.6 47.2 0.8 4.5 0.5 6.6 0.7 5.5 1.1 3.7 34.9 33.1 0.0 1.0 0.1 21.5 43.9 MND1 GAJ ENSG00000121211 "Meiotic nuclear divisions 1" Q9BWT6 4 153344649-153415118 "Predicted intracellular proteins" "DNA recombination, Meiosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 13.3;lymphoid tissue: 26.7;testis: 15.9" "Cell type enhanced" "Detected in many" "Early spermatids: 25.9;Erythroid cells: 30.9;Spermatocytes: 55.5;Spermatogonia: 96.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 1.3;T-reg: 1.7" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA043499 Supported NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 24: NB-4 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" "HPA043499: AB_2732506" "unprognostic (2.21e-2)" "unprognostic (6.46e-3)" "unprognostic (9.79e-2)" "unprognostic (1.61e-1)" "unprognostic (7.98e-2)" "unprognostic (2.97e-1)" "prognostic unfavorable (2.72e-4)" "unprognostic (6.21e-3)" "prognostic unfavorable (3.40e-4)" "unprognostic (5.28e-2)" "unprognostic (1.28e-2)" "unprognostic (9.43e-2)" "unprognostic (2.71e-8)" "unprognostic (7.65e-2)" "unprognostic (5.70e-2)" "unprognostic (9.84e-2)" "unprognostic (7.64e-2)" 0.5 0.5 1.1 4.7 1.2 13.3 2.5 1.0 2.0 0.7 0.7 4.4 3.0 0.7 1.2 3.3 0.5 1.0 0.4 1.1 1.3 0.6 1.3 0.8 12.0 1.4 1.1 0.3 0.3 0.0 0.3 2.4 1.2 0.5 5.1 0.0 0.9 0.9 1.3 2.1 2.6 1.5 1.1 1.8 1.6 15.9 1.3 26.7 0.4 0.5 14.0 1.3 1.3 1.7 38.6 17.7 52.7 30.6 0.7 7.2 20.9 35.1 15.4 31.4 25.6 32.8 26.1 74.4 5.8 8.5 29.5 15.7 52.3 15.8 39.9 47.7 19.9 39.1 17.3 42.9 1.1 88.2 17.9 1.9 3.3 24.4 21.1 7.8 10.7 86.0 71.0 91.9 26.8 21.5 124.1 116.0 39.1 17.9 17.8 74.1 18.2 35.8 19.3 9.7 26.5 23.3 15.7 17.7 30.0 26.5 14.7 72.1 2.6 24.1 34.8 28.1 32.6 79.0 96.0 58.8 24.1 69.6 28.9 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.0 1.3 0.0 0.3 0.0 0.0 0.4 0.0 0.1 1.7 0.1 1.1 1.2 1.0 2.0 1.1 1.3 1.4 1.1 1.2 1.1 1.3 1.7 0.2 0.0 0.5 2.6 1.9 2.8 1.8 5.1 0.0 0.0 2.2 4.6 0.6 2.8 0.7 0.0 0.0 14.5 1.0 4.1 1.9 0.3 25.9 3.5 1.6 1.3 0.0 30.9 1.6 0.5 20.6 3.6 2.0 5.7 0.0 11.8 1.4 1.0 12.5 0.0 2.6 4.3 4.1 2.5 5.0 20.5 0.9 2.4 3.6 1.9 0.1 0.0 1.0 2.0 23.3 0.6 1.6 2.2 7.7 1.2 0.7 0.1 1.0 0.0 6.6 0.9 8.6 55.5 96.3 10.2 1.4 2.5 2.5 1.5 10.3 2.7 MOGAT1 "DGAT2L, DGAT2L1, MGAT1" ENSG00000124003 "Monoacylglycerol O-acyltransferase 1" Q96PD6 2 222671658-222709930 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycerol metabolism, Lipid biosynthesis, Lipid metabolism" "Acyltransferase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "gallbladder: 16.8" "Cell type enhanced" "Detected in some" "Astrocytes: 8.1;Breast glandular cells: 7.2;Cholangiocytes: 7.2;Endometrial ciliated cells: 3.9;Exocrine glandular cells: 5.1;Glandular and luminal cells: 4.9;Hepatocytes: 3.2" "Cancer enhanced" "Detected in some" "pancreatic cancer: 0.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA049944, HPA076308" Uncertain Approved "Endoplasmic reticulum,Cytosol" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 30: Mammary glandular cells - Lactation" Cytosol "Endoplasmic reticulum" "HPA049944: AB_2680964, HPA076308: " "unprognostic (6.32e-2)" "unprognostic (2.38e-1)" "unprognostic (1.15e-1)" "unprognostic (1.41e-1)" "unprognostic (4.28e-3)" "unprognostic (4.39e-2)" "unprognostic (4.32e-2)" "unprognostic (9.44e-2)" "unprognostic (1.91e-1)" "unprognostic (8.59e-2)" "unprognostic (3.07e-3)" "unprognostic (4.99e-2)" "unprognostic (3.89e-1)" "unprognostic (9.03e-3)" 0.9 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.5 0.6 0.1 0.0 16.8 0.4 0.1 0.1 0.8 3.1 0.4 0.0 0.1 0.6 0.0 0.2 0.6 0.0 0.0 0.2 0.1 0.0 0.1 0.5 0.1 0.4 0.6 0.0 0.0 0.1 0.0 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.1 0.0 0.4 0.1 0.1 0.1 0.6 0.2 0.1 0.1 0.1 0.0 0.0 0.5 8.1 0.0 0.0 0.0 0.0 0.0 0.4 7.2 0.3 0.7 7.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.6 0.9 3.9 0.6 0.1 0.0 0.0 2.5 5.1 0.0 0.1 0.0 4.9 0.0 0.2 0.0 3.2 0.9 0.0 1.9 0.0 0.0 0.3 0.3 0.1 0.0 1.3 0.0 0.0 0.6 1.5 0.0 1.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.1 0.0 0.9 0.1 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 MOGAT2 "DGAT2L5, FLJ22644, MGAT2" ENSG00000166391 "Monoacylglycerol O-acyltransferase 2" Q3SYC2 11 75717838-75732958 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycerol metabolism, Lipid biosynthesis, Lipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 19 "intestine: 48.2;liver: 25.2" "Cell type enhanced" "Detected in some" "Distal enterocytes: 73.8;Hepatocytes: 79.6;Intestinal goblet cells: 36.2;Proximal enterocytes: 159.6;Undifferentiated cells: 32.4" "Cancer enhanced" "Detected in many" "liver cancer: 6.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Hep G2: 4.5;RPMI-8226: 2.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA028834 Uncertain NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 45: Enterocytes - Digestion" "HPA028834: AB_10601865" "unprognostic (5.63e-2)" "unprognostic (2.71e-2)" "unprognostic (6.37e-2)" "unprognostic (6.88e-3)" "unprognostic (1.15e-4)" "unprognostic (2.66e-3)" "unprognostic (1.28e-3)" "unprognostic (1.09e-1)" "unprognostic (1.42e-2)" "unprognostic (1.12e-1)" "unprognostic (4.21e-2)" "unprognostic (3.02e-1)" "unprognostic (1.24e-5)" "unprognostic (2.13e-3)" "unprognostic (1.84e-2)" "unprognostic (2.13e-1)" "unprognostic (2.83e-3)" 0.0 0.0 0.0 1.9 0.2 0.0 1.4 0.0 0.1 0.1 0.0 13.9 44.9 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.3 25.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 12.6 0.0 0.2 0.2 0.0 0.6 48.2 0.7 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.7 0.6 0.3 1.5 0.2 0.0 0.0 0.0 0.0 73.8 0.0 0.0 0.0 0.1 0.0 0.0 2.4 2.7 0.0 0.5 0.0 0.0 2.6 0.1 0.0 0.0 0.4 79.6 0.0 0.0 0.0 36.2 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 21.3 0.0 0.0 0.6 159.6 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 32.4 0.1 MVD MPD ENSG00000167508 "Mevalonate diphosphate decarboxylase" P53602 16 88651935-88663161 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Lyase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 147.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041404, HPA048250" Uncertain Approved "Cell Junctions,Cytosol" NA NA 170000 "Cluster 15: NK-cells - Transcription" "Cluster 37: Intestine - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 15: Hepatocytes - Hemostasis" Cytosol "Cell Junctions" "HPA041404: AB_2677457, HPA048250: AB_2680329" "unprognostic (1.67e-1)" "unprognostic (3.05e-1)" "unprognostic (2.42e-1)" "prognostic favorable (2.17e-4)" "unprognostic (1.89e-1)" "unprognostic (9.56e-2)" "unprognostic (9.26e-3)" "unprognostic (8.33e-2)" "unprognostic (6.68e-2)" "unprognostic (5.47e-2)" "unprognostic (2.51e-1)" "unprognostic (6.22e-2)" "unprognostic (1.19e-3)" "unprognostic (4.12e-2)" "unprognostic (1.69e-1)" "unprognostic (2.11e-1)" "unprognostic (5.00e-2)" 20.3 51.1 24.2 15.7 27.5 7.0 16.4 26.2 37.5 30.5 19.3 32.3 35.1 20.3 2.2 77.8 13.5 4.9 22.8 24.7 27.8 28.8 78.8 31.0 12.3 32.4 27.8 19.6 25.3 8.3 18.9 6.3 39.3 23.5 4.2 3.4 25.1 6.5 27.2 52.3 26.6 5.7 24.0 24.6 31.5 42.3 24.7 7.0 21.1 8.3 6.8 17.6 36.9 25.6 50.6 34.2 52.4 33.1 18.1 38.7 29.5 25.1 26.0 17.7 14.6 86.1 119.7 24.4 39.8 15.7 63.7 72.8 25.0 133.1 4.9 15.7 38.3 17.8 18.2 127.0 35.9 11.6 11.8 30.9 24.6 46.6 13.5 8.7 18.0 58.0 51.7 13.1 10.2 115.9 39.3 56.6 61.5 17.7 31.3 40.2 15.0 62.3 49.8 33.0 52.2 17.9 62.0 13.3 18.5 11.4 67.8 51.3 39.0 14.7 29.8 27.2 14.2 34.9 17.6 83.2 17.9 55.7 25.7 5.6 12.6 2.4 26.8 13.7 20.4 16.1 18.0 17.9 15.0 22.6 13.2 16.6 1.8 28.3 15.4 28.0 20.4 15.4 24.2 27.5 26.2 37.5 24.7 27.8 32.4 27.8 39.3 24.0 24.7 25.6 17.2 25.6 48.2 22.2 21.5 15.2 12.9 106.3 4.0 27.2 26.5 14.1 16.7 21.5 56.9 20.2 6.2 20.2 79.6 117.5 25.4 30.8 61.6 17.7 10.0 15.8 32.9 26.5 23.4 62.3 29.2 15.5 41.8 26.5 16.5 27.4 20.7 147.2 38.6 23.5 17.0 75.3 32.6 25.5 21.6 96.2 8.1 20.3 21.4 6.5 32.2 16.5 55.6 11.1 14.5 30.0 79.4 9.1 46.3 20.1 47.1 22.6 21.5 18.1 6.6 7.0 20.7 50.8 13.0 13.8 21.6 48.8 36.3 35.5 65.2 20.6 MYH11 "SMHC, SMMHC" ENSG00000133392 "Myosin heavy chain 11" P35749 16 15703135-15857028 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Muscle protein, Myosin" "Aortic aneurysm, Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 3322.6;seminal vesicle: 1665.5;urinary bladder: 2048.3" "Group enriched" "Detected in many" 8 "Peritubular cells: 1669.7;Sertoli cells: 624.5;Smooth muscle cells: 964.6" "Group enriched" "Detected in many" 5 "prostate cancer: 173.2;stomach cancer: 125.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.7;RPMI-8226: 1.4;U-698: 7.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "midbrain: 39.8" "CAB002302, HPA014539, HPA015310" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA 23000000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane, Cytosol" "CAB002302: AB_563902, HPA014539: AB_1234906, HPA015310: AB_1854261" "unprognostic (7.99e-2)" "unprognostic (3.07e-2)" "unprognostic (4.18e-2)" "unprognostic (9.21e-3)" "unprognostic (6.70e-2)" "unprognostic (2.75e-2)" "prognostic favorable (1.10e-5)" "unprognostic (1.41e-2)" "unprognostic (1.87e-1)" "unprognostic (3.44e-2)" "unprognostic (1.28e-1)" "unprognostic (1.14e-1)" "unprognostic (1.19e-3)" "unprognostic (4.06e-2)" "unprognostic (9.53e-2)" "unprognostic (5.00e-2)" "unprognostic (5.45e-3)" 172.9 38.6 5.0 109.1 17.2 0.2 78.4 5.5 14.5 372.3 11.1 3322.6 95.4 1074.6 219.7 759.7 606.1 250.6 74.8 5.3 5.2 27.9 9.2 108.9 9.5 9.0 7.0 144.0 10.7 2.8 11.6 68.2 7.1 762.7 293.2 0.4 83.3 1665.5 41.2 68.5 487.4 1053.2 5.8 46.0 832.5 60.9 7.2 2.9 46.0 34.6 5.3 2048.3 314.2 6.3 0.0 0.1 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.6 0.2 0.0 0.0 0.2 0.0 1.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.9 0.0 0.2 0.2 7.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.1 0.0 5.0 17.2 5.5 14.5 5.3 5.2 9.0 7.0 7.1 5.8 7.2 6.3 7.6 0.0 1.8 0.0 4.4 13.3 2.1 1.7 5.7 2.7 5.3 122.3 40.5 0.0 1.9 0.0 8.4 0.3 3.4 0.4 0.0 0.2 50.2 4.7 19.5 12.8 1.2 0.8 0.8 0.4 0.3 22.2 0.0 3.4 0.0 27.3 6.4 0.1 1.1 0.0 5.2 0.5 0.0 2.2 17.3 46.2 42.9 2.8 12.4 15.9 3.7 0.3 3.1 1.5 10.7 0.4 0.2 1669.7 2.4 5.6 0.1 0.2 2.5 1.9 624.5 4.3 964.6 3.1 8.8 3.5 18.6 0.0 5.7 34.7 0.4 2.6 N4BP3 LZTS4 ENSG00000145911 "NEDD4 binding protein 3" O15049 5 178113532-178126081 "Predicted intracellular proteins" Neurogenesis "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 15.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 35.7;Extravillous trophoblasts: 130.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "memory B-cell: 1.7;naive B-cell: 1.6;naive CD8 T-cell: 1.2;plasmacytoid DC: 2.1" "Group enriched" "Detected in many" 16 "B-cells: 1.7;dendritic cells: 2.1;T-cells: 1.2" "Cell line enhanced" "Detected in many" "BEWO: 14.9;MCF7: 21.2;RH-30: 20.3;SK-BR-3: 72.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030972, HPA030973, HPA061387" Approved Supported Nucleoplasm,Centrosome NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm Centrosome "HPA030972: AB_2673680, HPA030973: AB_10603574, HPA061387: " "unprognostic (1.84e-1)" "unprognostic (1.70e-2)" "unprognostic (4.96e-3)" "unprognostic (6.64e-3)" "unprognostic (2.06e-1)" "unprognostic (3.18e-3)" "unprognostic (1.88e-6)" "unprognostic (1.45e-1)" "unprognostic (1.61e-1)" "unprognostic (1.92e-2)" "unprognostic (3.28e-3)" "unprognostic (9.55e-2)" "prognostic favorable (2.38e-4)" "unprognostic (2.62e-1)" "unprognostic (1.16e-1)" "unprognostic (1.22e-1)" "unprognostic (1.06e-1)" 1.9 0.8 1.6 1.0 1.0 2.9 2.5 3.0 3.7 2.6 0.6 1.4 0.5 0.8 0.3 15.7 1.0 0.7 2.3 1.0 2.1 3.1 0.1 3.9 1.8 2.6 1.8 0.5 0.7 4.1 2.2 8.3 2.7 1.0 0.4 4.7 6.8 0.8 4.4 7.8 1.8 0.5 0.2 1.8 2.2 0.9 4.1 0.9 1.4 3.0 2.9 1.4 4.0 2.1 0.1 0.1 2.3 1.7 0.2 0.0 14.9 0.0 0.0 0.0 0.0 3.3 1.1 1.4 2.0 0.0 0.1 4.7 0.4 0.1 0.0 2.5 0.8 4.1 1.8 0.1 0.1 0.2 0.0 0.3 0.5 0.0 0.1 0.0 12.0 1.3 2.6 0.9 0.0 21.2 0.2 0.3 11.2 3.6 0.1 11.6 20.3 5.4 1.2 2.4 1.7 0.8 0.6 72.2 4.9 2.8 2.8 0.1 2.4 0.0 1.7 0.0 0.0 3.2 2.3 13.1 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.1 1.7 0.1 0.1 0.0 1.6 0.4 1.2 0.0 0.1 0.0 2.1 0.0 0.2 1.6 1.0 3.0 3.7 1.0 2.1 2.6 1.8 2.7 0.2 4.1 2.1 7.8 3.2 0.6 0.0 12.7 9.4 13.1 6.7 4.0 35.7 7.3 3.6 1.7 2.8 3.4 1.8 12.5 3.0 10.4 9.4 13.7 3.4 0.4 1.9 1.1 15.7 4.2 0.0 2.9 0.8 130.4 1.6 6.6 5.8 4.5 0.5 0.4 0.2 2.3 1.7 4.9 3.7 6.1 0.0 1.7 0.8 0.6 1.0 12.4 3.7 1.1 2.0 0.0 0.5 0.2 7.3 8.7 1.9 6.1 10.3 0.1 0.8 0.3 9.2 0.0 2.5 0.7 0.2 8.1 14.1 6.8 23.1 3.0 0.7 3.5 12.1 NCALD ENSG00000104490 "Neurocalcin delta" P61601 8 101686542-102124907 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 100.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 251.6;Inhibitory neurons: 460.2;Oligodendrocyte precursor cells: 281.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "NK-cell: 87.3" "Group enriched" "Detected in many" 13 "NK-cells: 87.3;T-cells: 42.2" "Cell line enhanced" "Detected in many" "AF22: 136.4;HDLM-2: 159.9;U-266/70: 39.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043245 Approved NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA043245: AB_2678385" "unprognostic (3.49e-1)" "unprognostic (1.55e-1)" "unprognostic (4.85e-2)" "unprognostic (4.97e-2)" "unprognostic (5.48e-3)" "unprognostic (2.60e-3)" "unprognostic (1.25e-1)" "unprognostic (5.63e-3)" "unprognostic (1.54e-1)" "unprognostic (2.48e-1)" "prognostic favorable (5.30e-4)" "unprognostic (2.79e-1)" "unprognostic (6.24e-2)" "unprognostic (9.16e-3)" "unprognostic (1.55e-1)" "unprognostic (7.87e-2)" "unprognostic (1.00e-2)" 21.4 7.3 30.3 9.4 43.4 1.8 44.0 0.0 62.5 13.5 0.0 22.3 6.0 7.6 4.4 12.6 39.6 12.6 12.1 52.4 11.3 14.9 15.1 19.7 13.6 3.6 13.3 37.5 10.0 1.9 13.7 10.0 15.3 12.3 8.8 15.9 100.6 14.9 15.4 18.0 10.2 11.0 1.2 8.3 11.2 7.3 29.4 5.5 5.2 11.6 11.1 11.1 4.0 21.6 6.9 9.8 136.4 0.5 1.1 22.3 0.0 2.3 0.3 0.1 0.0 0.1 0.1 9.0 3.0 10.4 0.6 0.0 1.0 0.0 0.0 159.9 1.0 0.7 0.0 0.0 0.0 6.1 0.9 4.3 0.0 0.3 0.0 0.0 0.0 0.2 0.0 19.3 0.8 0.2 1.2 2.4 1.5 0.0 0.0 3.7 0.0 0.4 22.0 0.3 0.6 13.4 0.0 3.1 5.7 22.5 0.9 4.8 0.2 1.6 0.3 0.2 0.4 39.3 5.6 0.1 0.3 0.1 2.2 0.4 0.3 0.3 42.2 0.2 37.1 0.9 16.0 24.8 5.0 0.6 3.9 20.6 1.3 87.3 0.3 0.4 17.5 13.6 30.3 43.4 0.0 62.5 52.4 11.3 3.6 13.3 15.3 1.2 29.4 21.6 17.3 0.0 2.6 11.8 0.5 4.2 0.5 1.0 0.0 14.6 88.6 74.4 7.5 14.3 3.2 0.0 25.0 3.2 28.9 1.7 7.9 9.6 12.8 32.2 5.0 11.3 21.0 4.0 251.6 1.2 13.0 39.8 4.1 23.8 2.5 20.5 14.6 15.0 1.9 13.5 460.2 4.3 61.1 2.6 6.9 6.6 2.8 2.8 103.2 75.9 0.8 46.6 64.9 281.0 26.5 3.5 0.5 1.5 7.1 1.3 0.0 19.5 26.0 4.7 26.3 91.0 24.5 1.5 1.8 3.0 3.1 3.0 17.4 19.4 0.4 1.1 NCAPD2 "CAP-D2, CNAP1, hCAP-D2, KIAA0159" ENSG00000010292 "Non-SMC condensin I complex subunit D2" Q15021 12 6493356-6531955 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA condensation, Mitosis" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 76.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 48.0;Late spermatids: 34.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012423, HPA036947, HPA037363" Approved Supported Nucleoplasm,Nucleoli,Cytosol NA Yes 34000 "Cluster 44: Non-specific - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "Nucleoplasm, Nucleoli" "CAB012423: , HPA036947: AB_10671367, HPA037363: AB_10672483" "unprognostic (1.51e-1)" "unprognostic (1.88e-1)" "unprognostic (2.20e-1)" "unprognostic (1.31e-2)" "unprognostic (1.03e-2)" "unprognostic (7.84e-2)" "prognostic unfavorable (1.79e-8)" "unprognostic (2.73e-3)" "unprognostic (1.45e-2)" "unprognostic (5.00e-2)" "unprognostic (5.41e-3)" "unprognostic (4.53e-1)" "prognostic unfavorable (1.13e-7)" "unprognostic (4.80e-3)" "unprognostic (1.18e-1)" "unprognostic (4.53e-1)" "unprognostic (8.75e-2)" 8.3 7.4 7.3 21.5 11.4 35.5 10.9 9.9 8.3 10.2 7.4 17.9 17.0 10.7 10.6 15.9 11.2 9.8 7.6 7.2 8.0 7.4 4.8 10.6 38.1 11.0 10.0 8.0 7.7 11.3 5.5 17.5 11.7 9.4 20.4 11.1 11.8 10.2 7.9 21.9 16.0 13.4 8.4 16.1 12.1 18.2 10.2 76.8 11.3 10.2 44.8 10.1 9.3 13.9 125.3 99.3 134.6 97.9 29.9 28.4 159.2 76.1 69.8 138.3 109.1 123.5 150.8 135.8 24.2 63.2 126.7 128.6 188.0 105.4 194.1 214.1 92.8 112.2 113.8 79.4 12.5 145.0 96.5 20.5 31.6 112.4 107.8 61.9 89.9 94.0 71.0 63.4 104.7 79.6 162.2 73.8 207.5 129.9 78.2 153.7 260.6 77.7 39.5 64.1 54.0 61.9 121.5 64.9 44.3 189.1 27.0 101.7 51.0 94.1 149.6 60.8 168.4 45.3 51.7 181.0 55.7 92.2 126.1 11.0 1.7 3.7 7.1 2.8 5.3 5.1 6.4 7.3 3.4 3.5 7.3 7.3 1.4 8.1 2.2 4.1 8.3 3.9 7.3 11.4 9.9 8.3 7.2 8.0 11.0 10.0 11.7 8.4 10.2 13.9 4.3 6.4 7.4 4.9 11.0 3.6 3.8 4.4 17.1 3.7 4.7 6.9 4.1 5.7 3.4 1.8 8.4 13.5 8.9 7.3 0.0 4.5 18.3 5.3 6.3 5.4 1.2 48.0 5.6 3.7 17.8 6.4 7.1 5.8 3.8 20.0 8.9 3.3 10.1 5.0 5.0 9.9 6.1 16.4 4.4 34.3 5.9 10.8 0.0 2.8 9.5 11.8 15.5 2.5 17.8 5.3 4.6 6.0 22.6 4.1 6.0 2.4 4.2 8.4 0.0 4.2 5.2 21.3 13.7 19.3 3.4 6.3 12.0 6.1 14.7 4.1 NCAPG "CAP-G, FLJ12450, hCAP-G, YCG1" ENSG00000109805 "Non-SMC condensin I complex subunit G" Q9BPX3 4 17810979-17844865 "Predicted intracellular proteins" "Cell cycle, Cell division, DNA condensation, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 13.9;lymphoid tissue: 15.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 59.3;Extravillous trophoblasts: 26.6;Plasma cells: 20.4;Spermatocytes: 63.7;Spermatogonia: 24.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Region enhanced" "Detected in single" "white matter: 1.6" "Low region specificity" "Detected in all" HPA039613 Uncertain NA Yes 9500 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "HPA039613: AB_10805481" "unprognostic (5.23e-2)" "unprognostic (3.37e-1)" "unprognostic (1.59e-3)" "prognostic unfavorable (8.28e-4)" "unprognostic (4.22e-2)" "unprognostic (1.12e-1)" "prognostic unfavorable (3.13e-6)" "unprognostic (1.18e-3)" "unprognostic (1.63e-2)" "unprognostic (6.70e-2)" "prognostic unfavorable (7.65e-5)" "unprognostic (3.44e-2)" "unprognostic (0.00e+0)" "unprognostic (1.94e-2)" "unprognostic (1.34e-1)" "unprognostic (1.67e-1)" "unprognostic (2.07e-1)" 0.7 0.5 0.1 4.1 0.1 13.9 0.9 0.5 0.1 0.7 0.2 3.0 3.8 0.6 0.0 3.5 0.2 0.9 0.3 0.0 0.2 0.2 0.7 0.6 8.7 0.6 1.2 0.2 0.2 0.1 0.1 3.0 0.7 0.3 2.4 0.3 0.7 0.0 0.2 3.5 3.2 1.0 1.2 2.1 1.9 5.6 0.3 15.8 0.3 0.1 8.7 1.2 1.0 0.2 45.1 28.3 63.8 42.2 4.0 7.8 23.1 56.8 22.2 55.0 55.8 36.3 26.8 66.8 11.3 16.0 47.6 19.9 54.5 22.1 74.8 30.5 27.0 53.6 37.3 29.8 0.2 38.4 20.3 1.5 1.5 40.7 18.6 8.8 27.9 28.9 53.1 74.1 55.0 13.4 44.1 36.9 32.8 26.1 27.9 42.8 57.4 28.0 16.6 13.9 50.0 29.7 51.2 10.9 15.7 27.2 25.6 21.3 23.2 52.5 23.6 30.0 78.9 23.2 23.3 56.1 21.7 39.1 35.8 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.6 0.4 0.1 0.1 0.5 0.1 0.0 0.2 0.6 1.2 0.7 1.2 0.3 0.2 0.3 0.0 1.1 0.0 3.3 2.4 0.6 1.9 1.2 0.2 0.6 0.6 0.2 0.0 0.8 0.0 0.0 11.7 1.6 2.9 0.0 0.1 15.8 0.9 1.9 1.7 1.8 59.3 0.2 0.0 26.6 3.8 7.1 2.3 1.3 14.2 2.2 0.5 9.5 0.0 0.4 3.1 2.0 2.6 2.9 9.5 0.6 3.7 1.8 1.0 0.7 0.3 3.1 0.5 0.5 0.2 0.1 0.0 20.4 0.4 0.2 0.0 0.0 0.2 0.0 0.2 4.3 63.7 24.3 11.0 1.1 2.2 3.7 0.7 5.6 1.3 NCAPH "BRRN1, CAP-H, hCAP-H" ENSG00000121152 "Non-SMC condensin I complex subunit H" Q15003 2 96335766-96377091 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, DNA condensation, Mitosis" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 35.2;lymphoid tissue: 37.4;testis: 35.4" "Cell type enhanced" "Detected in many" "Plasma cells: 26.3;Spermatocytes: 89.3;Spermatogonia: 29.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "T-reg: 6.2" "Group enriched" "Detected in many" 5 "granulocytes: 3.8;T-cells: 6.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA002647, HPA003008" Enhanced Supported Nucleoplasm,Cytosol Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol Nucleoplasm "HPA002647: AB_1078300, HPA003008: AB_1078301" "unprognostic (5.52e-2)" "unprognostic (7.37e-2)" "unprognostic (2.93e-2)" "unprognostic (2.85e-3)" "unprognostic (1.92e-1)" "unprognostic (7.51e-2)" "prognostic unfavorable (9.53e-6)" "prognostic unfavorable (6.73e-4)" "unprognostic (1.50e-3)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.02e-4)" "unprognostic (3.16e-2)" "unprognostic (0.00e+0)" "unprognostic (3.00e-2)" "unprognostic (2.38e-1)" "unprognostic (2.14e-1)" "unprognostic (2.30e-2)" 1.2 0.7 0.3 9.9 0.4 35.2 1.8 0.9 0.9 1.3 0.1 7.7 5.6 0.9 0.2 6.3 0.5 1.6 0.4 0.3 0.2 0.4 1.0 1.1 20.3 0.1 0.0 0.3 0.3 0.5 0.2 5.2 0.3 0.4 9.3 1.8 1.5 0.2 0.3 4.7 6.2 2.8 0.0 3.7 3.6 35.4 0.1 37.4 0.4 0.1 22.0 2.6 2.0 0.3 134.1 52.0 115.1 60.6 3.9 6.1 80.8 58.7 40.3 115.1 118.4 93.5 71.5 121.0 41.8 26.6 106.2 57.2 100.2 39.6 117.2 110.0 63.4 123.7 49.3 74.5 0.7 112.2 101.3 1.8 4.2 89.1 35.9 10.2 46.6 89.7 89.5 88.8 53.0 59.5 183.8 104.2 85.9 57.6 56.6 133.4 106.7 95.5 23.6 49.6 71.2 52.3 34.8 46.5 19.9 42.4 36.6 80.0 24.1 83.5 126.3 76.9 101.9 44.4 70.1 134.0 33.7 111.5 95.3 3.8 0.0 0.2 0.8 0.9 0.1 0.9 1.2 1.0 0.4 0.9 0.0 0.4 0.3 0.1 0.0 0.0 6.2 0.5 0.3 0.4 0.9 0.9 0.3 0.2 0.1 0.0 0.3 0.0 0.1 0.3 4.9 0.0 0.0 0.0 3.5 0.6 0.7 1.9 1.2 0.4 1.0 0.8 0.5 0.0 1.6 0.0 8.4 9.4 2.0 2.1 0.0 0.5 5.9 1.7 0.9 1.8 0.0 16.4 0.4 0.0 16.3 1.8 4.1 1.2 1.3 5.5 1.4 0.4 8.5 0.0 0.3 2.8 0.0 3.8 3.7 4.9 0.9 2.2 1.8 0.0 0.2 8.5 0.0 0.5 1.0 0.2 0.1 0.4 26.3 0.7 0.4 0.0 1.6 2.3 0.0 0.2 3.5 89.3 29.4 8.8 0.9 1.9 5.1 0.6 5.7 1.1 NDC80 "HEC, HEC1, hsNDC80, KNTC2, TID3" ENSG00000080986 "NDC80 kinetochore complex component" O14777 18 2571557-2616635 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 31.2;lymphoid tissue: 29.2" "Cell type enhanced" "Detected in many" "Erythroid cells: 63.4;Spermatocytes: 82.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 7.2;granulocytes: 8.3;T-cells: 11.3" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA066330 Supported Nucleoplasm,Centrosome NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Centrosome "HPA066330: AB_2685661" "unprognostic (1.96e-1)" "unprognostic (5.38e-2)" "unprognostic (2.96e-1)" "unprognostic (2.21e-3)" "unprognostic (1.87e-1)" "unprognostic (3.63e-2)" "prognostic unfavorable (2.53e-8)" "unprognostic (1.16e-2)" "unprognostic (2.58e-3)" "unprognostic (2.86e-2)" "unprognostic (3.19e-3)" "unprognostic (7.74e-2)" "unprognostic (0.00e+0)" "unprognostic (9.69e-3)" "unprognostic (1.69e-1)" "unprognostic (3.50e-2)" "unprognostic (1.71e-1)" 1.8 0.9 1.4 9.6 1.3 31.2 2.5 2.2 1.7 2.7 0.1 7.0 5.9 4.3 2.1 5.6 1.2 2.5 1.2 1.0 0.6 1.2 1.6 1.5 20.5 1.9 0.6 0.8 0.9 0.5 0.1 10.4 2.9 5.3 9.8 0.7 1.1 14.0 0.9 7.9 6.2 5.0 0.4 5.5 3.8 15.1 1.2 29.2 1.6 0.6 19.3 3.2 4.6 2.5 80.3 17.7 86.5 38.6 4.5 9.8 44.5 91.7 49.1 117.7 99.7 49.2 44.0 86.6 40.4 35.9 49.7 47.9 98.2 39.9 123.6 32.2 24.6 68.8 49.5 38.1 1.5 133.2 55.1 5.1 3.7 67.8 47.8 12.0 54.3 52.8 56.8 107.1 104.0 36.2 65.1 57.2 44.9 51.6 25.3 71.0 88.6 69.7 31.0 38.0 69.3 31.4 84.4 21.7 32.7 34.0 36.7 52.4 33.2 75.7 168.1 60.7 123.2 46.5 78.6 116.0 33.5 60.8 65.8 3.5 0.6 2.5 1.8 0.4 1.7 7.2 3.2 3.8 0.2 5.3 2.0 2.0 8.3 1.7 0.5 1.3 11.3 1.3 1.4 1.3 2.2 1.7 1.0 0.6 1.9 0.6 2.9 0.4 1.2 2.5 2.8 0.0 0.6 0.3 5.8 2.3 0.7 3.8 0.6 0.0 0.6 0.9 15.8 0.0 2.4 0.0 0.0 15.5 4.8 2.1 0.0 0.9 22.0 1.3 3.7 1.9 0.0 63.4 0.6 0.4 21.7 6.8 2.6 2.1 0.0 20.8 5.7 0.5 11.5 0.0 0.5 2.8 8.2 3.2 2.4 7.6 7.5 1.7 0.0 1.0 0.4 0.0 7.2 0.5 0.5 0.3 0.1 23.3 14.1 0.4 0.4 0.2 1.4 0.0 19.7 0.6 6.8 82.8 21.1 4.2 0.6 2.1 8.7 9.8 6.2 1.5 NEK2 "NEK2A, NLK1, PPP1R111, RP67" ENSG00000117650 "NIMA related kinase 2" P51955 1 211658657-211675630 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Meiosis, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 17.9;lymphoid tissue: 19.2;testis: 67.1" "Group enriched" "Detected in many" 4 "Early spermatids: 76.1;Spermatocytes: 244.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 5.7" "Low region specificity" "Detected in all" "CAB017530, HPA064967" Enhanced Supported Nucleoplasm,Centrosome NA Yes "Cluster 41: Basophils - Cellular respiration" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Centrosome" "CAB017530: AB_1126558, HPA064967: AB_2685393" "unprognostic (1.28e-1)" "unprognostic (2.33e-1)" "unprognostic (1.02e-1)" "unprognostic (8.51e-2)" "unprognostic (1.83e-1)" "unprognostic (1.35e-2)" "prognostic unfavorable (9.47e-6)" "prognostic unfavorable (9.11e-4)" "unprognostic (1.95e-2)" "unprognostic (2.00e-2)" "unprognostic (1.09e-3)" "unprognostic (8.49e-2)" "unprognostic (0.00e+0)" "unprognostic (8.21e-2)" "unprognostic (4.11e-2)" "unprognostic (1.25e-2)" "unprognostic (2.71e-1)" 0.7 0.4 0.5 5.3 0.4 17.9 1.5 0.9 0.6 1.1 0.6 5.9 7.4 1.3 0.5 4.4 2.2 0.8 0.4 0.5 0.3 0.3 0.7 0.7 9.0 0.4 0.2 0.4 0.1 0.1 0.0 3.2 0.3 2.5 7.6 1.5 0.8 0.2 0.4 4.3 6.9 2.0 0.2 1.7 2.7 67.1 0.6 19.2 0.4 0.2 10.6 1.3 1.6 0.9 86.0 60.5 45.3 32.6 2.6 4.5 49.7 32.4 30.1 55.4 47.5 32.3 81.7 45.1 15.2 25.2 35.1 44.5 39.9 24.2 69.6 69.5 33.2 21.6 51.4 44.2 0.4 43.2 28.3 1.4 2.9 42.9 45.9 13.4 36.3 45.2 59.9 76.9 56.0 23.6 47.3 28.8 43.0 55.0 30.5 46.2 69.2 68.7 19.7 24.2 41.0 45.0 46.6 51.5 39.3 38.4 79.4 25.1 19.0 27.6 54.1 54.8 88.3 31.6 62.6 59.6 24.1 32.6 46.8 1.2 0.1 0.1 0.1 0.1 0.0 0.5 0.1 0.1 0.0 0.4 0.3 0.2 0.7 1.5 0.1 0.2 1.6 0.3 0.5 0.4 0.9 0.6 0.5 0.3 0.4 0.2 0.3 0.2 0.6 0.9 0.1 0.0 0.5 0.3 1.7 2.9 0.7 3.8 0.6 11.3 1.9 2.2 0.5 0.0 2.9 0.0 0.0 9.4 0.8 1.9 0.0 0.2 76.1 15.2 0.7 0.8 0.0 39.6 0.8 0.2 14.1 1.4 5.6 1.5 0.0 3.6 3.6 0.7 5.8 3.3 0.0 3.2 10.2 2.5 1.1 39.0 2.5 2.1 0.0 0.0 0.0 1.6 2.1 0.0 0.1 0.0 2.5 0.7 5.4 0.7 2.1 0.1 5.2 1.8 6.6 0.0 1.5 244.2 26.1 8.6 1.7 1.4 2.0 0.9 9.5 1.4 NELFA "NELF-A, WHSC2" ENSG00000185049 "Negative elongation factor complex member A" Q9H3P2 4 1982717-2041903 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009960, HPA039858, HPA043931" Supported Enhanced "Nucleoplasm,Nuclear bodies" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Nuclear bodies" "CAB009960: AB_2288566, HPA039858: AB_2676711, HPA043931: AB_2678737" "unprognostic (1.66e-1)" "unprognostic (2.23e-1)" "unprognostic (3.01e-1)" "unprognostic (1.17e-1)" "unprognostic (3.32e-1)" "unprognostic (1.73e-2)" "prognostic unfavorable (4.35e-4)" "unprognostic (2.40e-1)" "unprognostic (1.12e-1)" "unprognostic (9.38e-2)" "unprognostic (2.74e-2)" "unprognostic (1.88e-3)" "unprognostic (1.58e-1)" "unprognostic (3.76e-2)" "unprognostic (2.77e-1)" "unprognostic (2.43e-1)" "unprognostic (3.05e-2)" 9.3 7.8 7.5 10.8 8.6 14.2 6.0 8.0 11.5 7.1 6.1 9.4 13.4 11.3 6.3 9.5 12.4 5.7 6.3 8.0 6.9 6.8 5.8 6.6 10.8 8.7 8.9 15.5 16.7 10.1 3.0 10.3 6.8 8.9 4.7 7.0 18.2 8.4 12.0 12.8 13.4 5.7 8.1 12.1 12.7 16.5 7.4 9.4 7.4 4.6 7.4 6.8 1.8 9.5 27.2 24.6 21.0 38.8 8.5 8.9 41.6 14.3 10.1 16.9 13.4 41.1 45.7 47.8 20.1 9.3 21.0 25.2 21.3 17.9 8.2 24.5 33.2 31.5 18.0 39.4 12.4 33.1 30.9 7.6 15.6 11.3 12.0 12.5 13.0 26.6 60.5 22.3 7.4 31.7 63.8 94.4 60.8 23.2 36.5 57.6 18.3 30.2 12.1 22.5 57.1 35.7 16.4 19.3 24.4 13.0 37.1 24.5 14.7 17.0 19.2 19.8 31.9 47.2 52.7 53.6 19.4 34.5 21.4 7.0 14.4 14.9 15.4 16.9 18.5 16.3 17.9 13.9 13.9 24.0 15.0 12.0 5.3 15.4 14.0 17.3 22.1 13.1 7.5 8.6 8.0 11.5 8.0 6.9 8.7 8.9 6.8 8.1 7.4 9.5 11.1 12.8 17.9 30.7 18.5 32.6 18.6 20.3 17.6 19.2 17.6 19.3 4.6 14.3 19.1 12.9 39.6 27.9 16.2 14.6 9.8 18.7 24.0 25.2 17.7 13.2 16.2 17.2 55.9 13.6 28.1 14.7 13.3 28.5 9.5 23.3 11.4 8.3 16.4 37.0 40.9 17.8 14.2 10.1 12.1 7.4 15.5 11.3 14.2 13.1 19.6 18.1 19.6 31.7 30.2 16.2 18.7 13.2 14.0 23.6 17.5 8.9 17.3 21.9 0.0 15.4 15.2 32.9 39.4 29.8 38.2 28.5 18.8 15.8 20.1 27.0 NFE2 NF-E2 ENSG00000123405 "Nuclear factor, erythroid 2" Q16621 12 54292111-54301015 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 112.5;lymphoid tissue: 45.3" "Cell type enriched" "Detected in some" 5 "Erythroid cells: 265.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 5 "basophil: 1489.2;neutrophil: 810.6" "Lineage enriched" "Detected in many" 6 "granulocytes: 1489.2" "Group enriched" "Detected in some" 5 "HEL: 376.9;K-562: 168.1;NB-4: 118.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA001914 Enhanced Approved "Nucleoplasm,Actin filaments" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 36: HEL - Hemostasis" "Cluster 6: Erythroid cells - Oxygen transport" "Nucleoplasm, Actin filaments" "HPA001914: AB_1079475" "unprognostic (2.68e-4)" "unprognostic (2.93e-2)" "unprognostic (2.20e-2)" "unprognostic (2.31e-2)" "unprognostic (2.33e-2)" "unprognostic (1.85e-1)" "unprognostic (1.20e-2)" "unprognostic (4.55e-2)" "unprognostic (4.12e-1)" "unprognostic (4.55e-2)" "unprognostic (3.47e-2)" "unprognostic (2.57e-3)" "unprognostic (9.90e-6)" "unprognostic (1.81e-2)" "unprognostic (8.99e-2)" "unprognostic (1.51e-2)" "unprognostic (3.46e-2)" 3.8 0.3 0.5 6.2 0.7 112.5 0.6 0.5 1.0 1.4 1.4 0.4 0.5 0.3 0.1 0.8 2.4 1.2 1.9 0.5 0.5 1.4 2.6 13.0 0.3 0.7 0.6 0.2 0.7 1.1 0.9 4.0 0.7 0.5 0.2 0.0 0.5 0.1 1.3 4.8 0.6 1.9 0.5 45.3 0.8 1.2 0.6 1.4 1.4 3.7 0.1 2.3 0.5 0.6 0.3 0.3 0.0 0.0 0.0 0.5 1.4 1.1 6.9 0.7 0.9 5.5 10.0 0.1 0.9 0.9 0.4 0.3 0.0 0.0 0.3 0.0 0.1 376.9 0.9 9.1 0.0 5.8 48.5 0.5 0.1 0.3 0.2 4.4 0.0 0.1 168.1 0.1 0.0 0.1 15.3 118.8 0.1 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 2.6 0.2 0.6 1.8 1.0 18.9 0.3 0.2 0.4 1.1 0.1 0.0 0.0 0.1 0.4 23.4 0.0 1489.2 241.7 232.3 0.6 66.7 1.0 0.3 0.8 0.5 156.7 0.5 1.0 0.7 810.6 1.1 42.0 2.7 0.2 160.2 0.5 0.7 0.5 1.0 0.5 0.5 0.7 0.6 0.7 0.5 0.6 0.6 0.0 0.0 3.0 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.1 1.5 0.1 0.0 0.0 0.2 1.3 0.0 0.0 0.1 5.9 0.1 0.0 0.0 0.0 265.6 0.0 0.0 0.5 0.4 0.0 0.1 3.8 0.1 0.4 0.2 1.0 0.0 0.0 0.0 0.0 22.8 0.2 19.0 0.0 44.3 1.8 0.0 33.9 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.1 0.8 0.0 0.0 0.1 0.0 0.3 1.3 0.0 0.3 1.2 1.1 0.0 0.1 0.1 NHSL1 "bA43P8.1, C6orf63, KIAA1357" ENSG00000135540 "NHS like 1" Q5SYE7 6 138422043-138692571 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 23.2" "Cell type enriched" "Detected in many" 4 "Astrocytes: 502.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.6;non-classical monocyte: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Hep G2: 46.2;TIME: 64.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029966, HPA029967" Uncertain Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 64: Astrocytes - Nervous system maintenance" "Nuclear membrane" Nucleoplasm "HPA029966: AB_10601972, HPA029967: AB_2673271" "unprognostic (1.85e-1)" "unprognostic (9.71e-2)" "unprognostic (6.19e-2)" "unprognostic (1.81e-1)" "unprognostic (1.01e-1)" "unprognostic (1.93e-1)" "unprognostic (3.27e-1)" "unprognostic (8.34e-2)" "unprognostic (5.21e-2)" "unprognostic (9.99e-2)" "unprognostic (1.10e-1)" "unprognostic (8.00e-2)" "unprognostic (4.19e-2)" "unprognostic (3.73e-2)" "unprognostic (1.52e-1)" "unprognostic (6.55e-2)" "unprognostic (4.06e-2)" 4.1 1.2 15.7 2.4 14.1 0.3 2.5 9.7 8.5 2.4 16.6 13.2 15.8 1.2 4.6 10.4 1.0 3.0 15.7 14.6 11.2 5.8 14.8 12.8 1.0 16.2 15.9 0.5 3.3 2.1 1.1 4.3 10.7 0.8 11.4 2.6 3.5 0.5 0.5 11.4 23.2 3.2 9.2 2.6 7.8 0.4 14.4 0.6 1.4 0.8 2.1 2.7 4.5 5.6 5.5 4.7 32.8 13.8 9.4 11.4 12.2 4.8 2.3 1.7 1.6 6.2 3.1 0.0 6.0 4.1 3.1 12.3 20.0 12.5 0.9 0.4 13.4 3.4 2.2 46.2 13.8 12.4 2.3 16.7 7.0 0.9 14.1 1.8 23.3 1.9 0.0 1.8 7.2 10.7 1.3 1.0 13.1 3.1 8.8 14.1 3.4 1.0 11.2 13.7 12.4 0.0 5.1 10.3 33.4 21.5 3.3 3.9 64.3 4.6 4.5 4.6 13.3 1.2 2.7 0.0 0.4 5.0 25.5 0.4 1.2 0.2 0.0 1.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.6 0.3 0.0 0.2 15.7 14.1 9.7 8.5 14.6 11.2 16.2 15.9 10.7 9.2 14.4 5.6 6.2 60.9 66.9 502.1 0.5 42.8 3.1 6.6 4.0 0.6 4.1 6.0 22.7 15.7 9.9 29.5 29.2 14.2 0.1 84.1 9.8 3.7 1.1 19.0 1.8 9.3 20.3 2.7 3.3 3.6 3.5 15.6 16.8 16.9 8.8 1.5 26.4 38.1 4.5 37.0 2.9 32.3 6.1 9.4 7.1 0.4 0.6 7.5 21.4 104.0 0.6 15.4 0.0 79.9 2.3 3.9 43.0 0.0 0.1 5.4 87.3 15.8 22.0 1.4 6.6 2.3 4.7 0.0 1.1 7.7 49.2 43.4 1.8 0.8 45.4 10.5 NMNAT3 PNAT3 ENSG00000163864 "Nicotinamide nucleotide adenylyltransferase 3" Q96T66 3 139560180-139678017 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 50.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 567.3;Alveolar cells type 2: 566.9;Club cells: 217.6;granulocytes: 278.8;Late spermatids: 223.3;Respiratory ciliated cells: 250.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 31.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA039077, HPA057402" Approved Supported Mitochondria NA NA "Cluster 11: Basophils - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 29: U-266 - Adaptive immune response" "Cluster 11: Alveolar cells - Smell perception" Mitochondria "HPA039077: AB_2676336, HPA057402: AB_2683427" "unprognostic (9.45e-3)" "prognostic favorable (9.67e-4)" "unprognostic (2.29e-1)" "unprognostic (1.56e-3)" "unprognostic (2.33e-2)" "unprognostic (2.33e-1)" "unprognostic (2.77e-3)" "unprognostic (6.22e-2)" "unprognostic (9.69e-2)" "unprognostic (1.92e-1)" "prognostic favorable (7.29e-5)" "unprognostic (4.57e-2)" "prognostic favorable (1.95e-5)" "unprognostic (4.13e-2)" "unprognostic (1.63e-1)" "unprognostic (1.44e-1)" "unprognostic (3.07e-1)" 7.5 7.4 17.7 4.9 26.7 19.3 8.3 46.5 45.4 6.7 8.2 6.9 9.2 9.4 8.1 5.4 13.6 5.4 11.6 21.5 10.9 9.2 6.6 4.3 4.8 8.6 5.3 20.1 12.0 8.9 5.5 2.2 15.1 6.5 7.5 30.6 9.3 5.5 29.6 19.0 7.8 5.6 2.5 5.4 5.6 11.3 14.6 3.0 7.6 20.3 5.3 5.5 6.8 50.1 9.2 3.6 4.0 4.6 0.9 0.9 5.0 3.7 0.4 0.6 0.5 5.1 6.4 5.9 10.8 0.7 4.3 4.5 3.0 1.2 0.7 5.8 5.3 31.4 9.1 6.9 2.4 5.6 5.5 1.4 7.8 1.0 1.7 9.3 0.5 3.6 5.0 13.1 0.6 6.2 5.3 4.6 9.0 16.5 3.7 4.4 4.5 4.3 1.2 6.3 9.2 5.4 9.2 4.8 3.3 7.3 12.6 15.6 5.6 5.7 12.6 7.2 5.5 23.1 11.0 4.2 3.8 9.0 5.4 11.4 3.6 2.2 2.8 3.4 1.9 2.7 2.4 2.4 2.8 4.5 3.4 3.6 7.0 4.0 3.4 2.9 1.6 1.7 17.7 26.7 46.5 45.4 21.5 10.9 8.6 5.3 15.1 2.5 14.6 50.1 5.5 567.3 566.9 34.9 1.9 4.1 6.3 6.6 6.2 2.7 8.2 7.1 9.7 8.6 217.6 9.2 4.2 0.4 0.8 2.3 11.7 3.3 128.2 2.1 2.4 38.8 6.7 27.1 37.2 3.1 0.2 38.3 3.1 1.7 278.8 9.7 2.5 2.7 2.0 1.7 26.0 6.5 8.2 4.1 2.9 223.3 7.8 31.8 7.2 12.2 1.8 12.3 0.0 46.8 16.9 0.8 2.9 6.4 0.7 6.1 3.5 16.1 250.6 18.5 6.6 13.2 3.8 67.1 3.5 4.4 9.7 0.1 21.5 5.9 10.6 4.8 NOD2 "BLAU, CARD15, CD, CLR16.3, IBD1, NLRC2, PSORAS1" ENSG00000167207 "Nucleotide binding oligomerization domain containing 2" Q9HC29 16 50693588-50734041 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins" "Immunity, Innate immunity" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 13.6;esophagus: 11.7;skin 1: 14.4;vagina: 12.3" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 8.3;Kupffer cells: 9.0;Langerhans cells: 22.5;Macrophages: 15.2;monocytes: 15.6;Suprabasal keratinocytes: 15.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 4 "classical monocyte: 23.0;eosinophil: 6.0;intermediate monocyte: 13.1;myeloid DC: 21.3;neutrophil: 10.5;non-classical monocyte: 9.0" "Group enriched" "Detected in many" 5 "dendritic cells: 21.3;granulocytes: 10.5;monocytes: 23.0" "Cell line enhanced" "Detected in some" "HMC-1: 11.6;T-47d: 5.8;THP-1: 7.3;U-266/70: 15.9;U-266/84: 7.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA041985, HPA054494" Enhanced Approved "Golgi apparatus,Cytosol" No NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Golgi apparatus, Cytosol" "HPA041985: AB_2677780, HPA054494: AB_2682505" "unprognostic (1.01e-1)" "unprognostic (4.38e-1)" "unprognostic (1.07e-1)" "unprognostic (1.02e-3)" "unprognostic (9.91e-3)" "unprognostic (5.84e-2)" "unprognostic (5.90e-3)" "unprognostic (1.23e-1)" "unprognostic (4.17e-1)" "unprognostic (3.88e-2)" "unprognostic (6.94e-3)" "unprognostic (1.48e-2)" "unprognostic (2.31e-9)" "unprognostic (4.38e-2)" "unprognostic (1.08e-2)" "unprognostic (1.53e-1)" "unprognostic (1.13e-1)" 1.5 0.5 0.5 5.9 0.2 13.6 1.5 0.2 1.0 5.6 0.7 0.9 1.5 0.6 0.3 11.7 0.9 1.3 0.7 0.2 0.4 0.6 1.7 4.3 2.7 1.0 0.9 0.4 0.3 0.2 0.4 1.2 0.7 0.9 0.9 0.0 4.3 0.4 0.6 14.4 1.3 1.8 0.7 4.4 1.4 0.5 1.4 0.8 0.4 0.3 2.3 1.6 12.3 0.8 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.2 0.0 11.6 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 2.8 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.2 0.1 0.0 1.5 0.0 0.0 5.8 7.3 0.0 0.0 0.0 0.0 0.0 15.9 7.2 0.0 0.3 0.1 0.0 3.0 23.0 6.0 0.4 13.1 0.7 0.1 1.3 1.4 21.3 0.0 0.1 0.5 10.5 3.4 9.0 1.0 0.9 11.1 0.5 0.2 0.2 1.0 0.2 0.4 1.0 0.9 0.7 0.7 1.4 0.8 0.2 0.0 3.7 0.0 1.9 5.9 0.3 1.2 0.0 0.0 1.4 1.1 0.4 1.5 2.3 0.0 0.0 0.0 1.9 0.0 0.0 0.1 0.0 5.6 0.8 0.6 1.2 0.8 0.1 0.0 0.0 0.4 0.0 8.3 1.3 0.5 0.0 0.5 2.5 0.0 0.1 0.0 2.0 9.0 22.5 0.0 0.0 15.2 1.8 1.9 15.6 0.0 1.0 0.0 0.2 0.0 0.0 0.4 4.3 0.4 0.0 0.1 1.0 0.0 0.0 0.1 0.4 0.1 0.4 6.1 15.5 0.3 2.3 0.1 0.1 0.3 NPAS1 "bHLHe11, MOP5, PASD5" ENSG00000130751 "Neuronal PAS domain protein 1" Q99742 19 47019837-47045775 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.3;skin 1: 7.7" "Group enriched" "Detected in many" 4 "Cone photoreceptor cells: 16.7;Gastric mucus-secreting cells: 27.0;Inhibitory neurons: 28.3" "Cancer enhanced" "Detected in many" "testis cancer: 5.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 9.9;Daudi: 10.2;HEK 293: 11.1;HMC-1: 9.0;NB-4: 18.1;U-266/84: 11.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA043364, HPA072259" Approved Approved Nucleoplasm NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA043364: , HPA072259: AB_2686500" "unprognostic (2.34e-3)" "unprognostic (6.25e-2)" "unprognostic (7.32e-4)" "unprognostic (1.38e-1)" "unprognostic (6.24e-2)" "unprognostic (2.46e-2)" "unprognostic (2.76e-3)" "unprognostic (2.21e-2)" "unprognostic (1.09e-1)" "unprognostic (3.75e-1)" "unprognostic (5.91e-2)" "unprognostic (2.64e-1)" "unprognostic (2.14e-8)" "unprognostic (8.82e-2)" "unprognostic (2.07e-1)" "unprognostic (1.06e-1)" "unprognostic (4.20e-2)" 0.9 0.4 3.1 0.3 1.8 0.2 0.7 0.3 6.3 0.4 1.9 0.4 0.0 0.1 0.0 1.0 0.6 0.0 1.1 5.4 2.8 1.7 0.6 0.4 0.5 2.9 2.5 0.2 0.6 0.0 1.3 0.1 4.3 0.4 0.0 0.5 0.4 0.0 0.1 7.7 0.4 0.1 0.7 2.8 2.7 0.6 1.5 0.1 0.5 0.0 0.3 0.4 0.7 2.0 0.2 2.4 0.3 0.5 0.2 0.2 0.0 9.9 0.3 0.1 0.4 0.7 0.5 10.2 2.2 8.1 0.4 0.2 2.1 0.2 0.1 0.7 11.1 0.8 1.2 2.5 0.0 5.5 9.0 0.9 0.4 0.0 0.1 0.6 0.2 1.3 3.5 0.8 1.3 0.9 0.4 18.1 2.4 0.4 1.7 0.9 0.4 0.8 0.6 0.6 0.7 0.6 0.8 0.3 2.4 0.8 2.1 1.7 0.1 0.2 0.9 0.1 0.2 5.4 11.5 2.2 1.2 1.1 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 1.8 0.3 6.3 5.4 2.8 2.9 2.5 4.3 0.7 1.5 2.0 0.1 0.0 0.6 1.6 1.1 0.8 1.4 1.1 1.8 0.7 2.2 2.5 1.1 0.0 1.1 0.0 16.7 0.0 0.1 0.3 0.0 0.6 0.1 0.4 0.2 0.2 1.2 2.7 5.7 0.4 0.1 0.5 27.0 0.4 0.0 0.7 0.0 0.1 0.3 0.0 28.3 1.4 2.0 0.0 0.0 0.0 0.0 0.4 0.0 1.0 0.0 5.4 0.0 2.0 1.2 1.0 0.2 0.0 2.6 1.5 0.0 0.9 2.0 5.4 0.0 0.1 1.1 0.4 2.1 2.2 2.3 0.0 1.2 0.1 0.6 1.2 NRG3 ENSG00000185737 "Neuregulin 3" P56975 10 81875194-82987179 "Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 17.3;retina: 5.2" "Group enriched" "Detected in some" 18 "Astrocytes: 2921.6;Excitatory neurons: 3761.0;Inhibitory neurons: 3088.3;Oligodendrocyte precursor cells: 1175.2" "Cancer enhanced" "Detected in many" "melanoma: 2.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 1.3;SK-MEL-30: 2.7;U-2 OS: 2.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075789 Uncertain Vesicles "Secreted in brain" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA075789: " "unprognostic (6.15e-3)" "unprognostic (2.43e-2)" "unprognostic (1.65e-5)" "unprognostic (1.89e-1)" "unprognostic (7.03e-4)" "unprognostic (1.85e-2)" "unprognostic (1.06e-1)" "unprognostic (7.05e-2)" "unprognostic (9.33e-2)" "unprognostic (1.82e-1)" "unprognostic (1.21e-1)" "unprognostic (3.75e-2)" "unprognostic (3.31e-4)" "unprognostic (1.04e-1)" "unprognostic (7.68e-3)" "unprognostic (7.27e-4)" 0.1 0.4 16.4 0.3 11.4 0.0 1.3 0.0 17.3 0.1 0.0 0.4 0.1 0.0 0.0 0.1 4.7 2.8 0.4 16.1 2.6 0.7 0.5 0.7 0.1 1.2 6.3 0.0 0.1 0.1 2.0 0.3 0.4 0.1 0.1 5.2 2.6 0.2 0.0 0.6 0.1 0.1 2.5 0.1 0.3 1.8 9.9 0.0 0.2 0.1 0.0 0.1 0.0 3.5 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 2.7 0.2 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.4 11.4 0.0 17.3 16.1 2.6 1.2 6.3 0.4 2.5 9.9 3.5 0.1 0.0 0.0 2921.6 0.1 0.0 0.0 0.0 0.0 15.9 0.7 0.6 0.8 2.8 0.0 0.0 2.1 0.0 0.1 0.0 0.0 0.9 31.4 0.0 0.0 0.7 0.0 0.0 3761.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 9.7 0.0 0.0 0.0 3088.3 0.0 0.0 0.0 0.0 12.8 0.6 0.1 0.0 148.0 0.0 6.7 0.0 1175.2 50.2 0.2 0.0 0.7 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.0 0.2 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 NSDHL "H105e3, SDR31E1, XAP104" ENSG00000147383 "NAD(P) dependent steroid dehydrogenase-like" Q15738 X 152830967-152869729 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Disease variant, Ichthyosis, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 53.0;Hepatocytes: 55.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000248, HPA000571" Enhanced Enhanced "Endoplasmic reticulum,Lipid droplets" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 37: Intestine - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Endoplasmic reticulum" "Lipid droplets" "HPA000248: AB_1079507, HPA000571: AB_1079506" "unprognostic (1.84e-1)" "prognostic favorable (5.65e-4)" "unprognostic (2.66e-1)" "unprognostic (1.81e-1)" "unprognostic (1.03e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (5.04e-4)" "unprognostic (1.03e-1)" "unprognostic (5.70e-2)" "unprognostic (4.32e-2)" "unprognostic (5.62e-2)" "unprognostic (2.63e-1)" "prognostic favorable (6.09e-5)" "unprognostic (3.53e-2)" "unprognostic (1.36e-1)" "unprognostic (3.91e-2)" "unprognostic (4.79e-2)" 24.0 38.8 13.2 10.2 12.6 8.9 20.2 14.2 13.3 20.3 13.7 13.9 17.6 13.6 44.5 51.7 14.9 7.9 22.4 13.7 14.3 14.9 50.4 12.9 9.1 16.8 15.4 10.3 10.6 12.9 8.8 10.3 18.5 14.8 13.5 10.4 16.7 21.3 10.1 22.6 24.2 12.5 13.4 9.5 13.8 8.9 15.2 9.9 13.3 10.9 18.1 12.1 24.1 15.1 135.6 48.9 65.5 33.8 54.9 41.5 36.2 26.3 35.2 46.9 59.3 68.5 71.7 67.0 86.0 35.9 174.2 67.6 85.5 122.1 41.3 22.0 49.5 27.9 44.7 70.3 39.8 27.6 21.1 51.1 46.3 92.2 23.0 20.2 44.2 28.7 46.4 29.1 36.1 60.1 27.3 35.8 26.0 67.4 58.1 19.9 47.4 54.6 98.9 55.7 23.4 26.5 23.4 34.6 28.4 44.9 23.1 35.0 38.7 21.6 35.4 52.3 51.0 40.9 29.4 114.9 40.0 42.4 20.8 21.0 19.6 18.7 16.3 18.7 16.4 19.1 16.1 14.1 19.4 15.1 11.6 12.7 2.2 19.7 14.2 17.4 20.4 15.2 13.2 12.6 14.2 13.3 13.7 14.3 16.8 15.4 18.5 13.4 15.2 15.1 7.1 12.8 16.7 5.9 6.3 10.8 12.8 53.0 10.8 4.3 11.7 6.1 25.0 15.7 29.0 12.9 0.0 21.5 6.1 9.6 9.8 20.1 13.3 15.5 6.6 9.2 6.0 13.0 2.2 20.3 22.0 9.0 8.2 15.5 8.2 14.0 7.5 55.0 18.6 1.7 2.2 10.2 26.4 8.7 9.6 8.0 8.4 7.9 5.4 1.0 11.0 10.6 7.2 2.5 5.7 21.4 11.9 9.1 11.3 10.4 25.2 16.5 25.4 6.2 0.0 5.9 12.5 3.7 7.8 19.4 12.1 18.6 5.3 25.1 11.2 16.4 NSG1 "D4S234E, NEEP21, P21" ENSG00000168824 "Neuronal vesicle trafficking associated 1" P42857 4 4348140-4419058 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 95.7;pituitary gland: 135.1;skin 1: 120.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 222.4;Cytotrophoblasts: 120.2;Granulosa cells: 128.8;Melanocytes: 291.7;Suprabasal keratinocytes: 178.2" "Cancer enriched" "Detected in many" 4 "melanoma: 61.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 45.2;MAIT T-cell: 61.9;memory CD4 T-cell: 42.2;memory CD8 T-cell: 37.1;naive CD8 T-cell: 27.6" "Lineage enriched" "Detected in many" 57 "T-cells: 61.9" "Cell line enhanced" "Detected in many" "HAP1: 84.7;SCLC-21H: 168.6;SH-SY5Y: 82.5;SK-MEL-30: 80.9;TIME: 204.6;U-698: 75.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 52: Non-specific - Transcription" "unprognostic (3.21e-3)" "unprognostic (2.33e-1)" "unprognostic (5.29e-3)" "unprognostic (7.60e-2)" "unprognostic (8.06e-2)" "unprognostic (1.49e-1)" "unprognostic (1.32e-3)" "unprognostic (3.47e-2)" "unprognostic (2.06e-1)" "unprognostic (1.91e-3)" "prognostic favorable (9.49e-4)" "unprognostic (2.50e-1)" "unprognostic (6.85e-2)" "unprognostic (4.21e-2)" "unprognostic (7.33e-2)" "unprognostic (2.85e-1)" "unprognostic (7.41e-2)" 5.0 25.3 29.0 4.2 33.1 1.0 6.0 59.6 50.7 17.1 5.3 7.9 6.8 7.8 2.1 30.7 20.1 1.3 5.9 18.4 95.7 4.4 0.5 1.5 3.2 57.1 64.8 46.3 1.8 0.1 135.1 18.3 58.8 22.8 7.1 32.3 6.7 18.2 0.7 120.9 5.8 6.9 24.2 2.2 8.0 16.0 45.4 9.5 0.5 3.0 3.5 13.3 30.1 24.2 0.2 0.1 0.8 0.5 0.0 0.0 14.6 0.3 0.0 0.2 0.0 1.3 0.4 0.0 10.4 0.5 3.3 2.4 84.7 5.5 0.4 0.0 3.0 0.0 0.2 0.0 4.1 0.0 0.0 0.1 12.0 0.0 2.3 0.0 14.6 22.3 0.0 0.1 1.3 0.0 6.8 0.5 10.1 0.1 0.4 0.1 0.0 0.4 0.0 4.8 168.6 82.5 0.6 0.2 80.9 7.0 0.9 0.3 204.6 0.0 13.0 0.2 0.3 0.1 0.4 75.9 0.1 0.2 0.4 0.2 0.1 0.1 45.2 0.1 61.9 0.1 42.2 37.1 0.1 0.1 10.4 27.6 1.0 0.9 0.2 0.1 4.5 15.7 29.0 33.1 59.6 50.7 18.4 95.7 57.1 64.8 58.8 24.2 45.4 24.2 1.6 9.6 0.0 5.9 0.4 86.8 83.4 47.9 31.3 222.4 0.7 24.3 0.0 0.0 13.2 0.0 4.2 120.2 6.0 0.0 0.0 0.0 31.2 10.3 1.4 2.1 2.4 0.0 16.6 0.0 15.2 24.9 0.0 16.4 1.3 128.8 1.8 0.0 8.2 8.4 32.2 0.0 4.1 0.0 13.6 44.2 3.1 1.3 291.7 6.5 0.4 6.4 20.6 1.5 4.0 0.1 0.2 5.7 0.7 19.9 0.0 20.4 1.7 24.3 0.0 0.2 10.8 2.9 14.4 44.8 178.2 76.8 17.0 96.0 0.3 77.0 NUAK2 "FLJ90349, SNARK" ENSG00000163545 "NUAK family kinase 2" Q9H093 1 205302063-205321745 "Enzymes, Metabolic proteins, Predicted membrane proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 56.7;vagina: 45.3" "Cell type enhanced" "Detected in many" "Ductal cells: 46.9;Endometrial ciliated cells: 45.3;Glandular and luminal cells: 52.4;Intestinal goblet cells: 43.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 120.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 44.1;RPMI-8226: 36.1;RPTEC TERT1: 40.9;SuSa: 45.6" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA008958 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Cytosol" "HPA008958: AB_1080040" "unprognostic (2.24e-2)" "unprognostic (6.33e-2)" "unprognostic (1.17e-1)" "prognostic unfavorable (3.01e-7)" "unprognostic (8.24e-3)" "unprognostic (1.58e-2)" "unprognostic (3.00e-2)" "unprognostic (1.08e-2)" "unprognostic (1.74e-1)" "unprognostic (9.19e-2)" "prognostic favorable (7.94e-6)" "unprognostic (3.71e-2)" "unprognostic (3.17e-2)" "unprognostic (4.90e-2)" "unprognostic (5.80e-2)" "unprognostic (4.54e-2)" "unprognostic (1.61e-1)" 2.1 3.7 1.3 7.7 1.9 11.4 0.9 4.6 1.7 31.0 3.2 8.0 16.5 1.6 1.3 56.7 4.0 1.7 1.2 1.2 1.3 28.2 5.1 10.3 11.5 2.1 1.8 1.3 16.0 0.8 3.0 4.4 2.0 1.9 8.8 0.5 15.1 1.6 0.7 22.4 12.5 1.2 1.4 13.1 2.5 3.7 2.2 3.9 16.1 1.1 8.0 3.1 45.3 4.1 4.3 23.1 13.7 0.6 0.3 0.6 44.1 5.5 5.7 14.7 5.9 24.4 0.8 7.0 3.2 1.5 24.1 8.3 3.2 8.3 6.3 0.0 0.4 0.0 1.4 4.2 9.3 0.0 0.1 2.6 6.1 8.6 5.0 3.3 0.7 0.0 0.9 1.7 2.8 1.0 0.0 0.1 8.9 3.1 0.7 0.0 1.0 36.1 40.9 0.1 2.1 0.2 1.6 6.5 0.7 45.6 6.6 0.1 1.7 5.3 2.5 0.6 8.7 12.1 2.0 4.4 0.8 0.0 2.1 11.2 16.5 40.1 10.3 11.8 7.6 37.9 12.7 12.3 10.4 39.3 27.9 21.9 120.4 17.5 13.1 4.1 8.1 17.4 1.3 1.9 4.6 1.7 1.2 1.3 2.1 1.8 2.0 1.4 2.2 4.1 2.0 6.4 6.8 0.3 28.0 1.1 3.2 3.7 13.1 1.1 1.9 2.2 2.7 20.0 2.9 33.1 0.0 9.2 7.1 34.9 5.9 46.9 2.0 45.3 7.5 5.9 10.8 2.7 0.1 1.8 29.1 3.7 7.7 52.4 0.0 2.4 0.7 2.6 4.7 0.0 0.4 43.0 18.3 12.3 11.1 2.1 0.0 8.9 7.2 3.7 38.5 1.3 18.6 0.5 3.5 6.9 7.8 0.0 18.5 2.5 18.3 17.2 7.7 0.5 6.6 2.4 5.5 0.9 1.1 21.5 5.4 4.1 5.7 0.5 22.0 0.5 NUF2 "CDCA1, CT106, NUF2R" ENSG00000143228 "NUF2 component of NDC80 kinetochore complex" Q9BZD4 1 163266576-163355764 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 28.4;lymphoid tissue: 26.0;testis: 53.5" "Cell type enhanced" "Detected in many" "Erythroid cells: 60.8;Spermatocytes: 208.2;Spermatogonia: 40.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "T-reg: 4.3" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA059692, HPA076604" Supported Nucleoplasm,Kinetochore,Cytosol Yes Yes "Cluster 35: T-regs - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Kinetochore, Cytosol" "HPA059692: AB_2684103, HPA076604: " "unprognostic (9.41e-2)" "unprognostic (2.61e-1)" "unprognostic (2.56e-1)" "unprognostic (5.32e-3)" "unprognostic (6.20e-2)" "unprognostic (3.77e-2)" "prognostic unfavorable (1.04e-5)" "prognostic unfavorable (9.16e-4)" "prognostic unfavorable (4.83e-4)" "unprognostic (8.45e-2)" "prognostic unfavorable (9.75e-4)" "unprognostic (3.70e-2)" "unprognostic (0.00e+0)" "unprognostic (9.79e-2)" "unprognostic (7.88e-2)" "unprognostic (2.69e-1)" "unprognostic (5.96e-2)" 0.8 0.6 0.5 6.9 0.8 28.4 1.2 0.5 0.8 1.0 0.4 4.2 4.3 1.1 0.3 5.8 0.4 1.0 0.3 0.6 0.6 0.3 0.7 0.9 18.2 0.9 0.8 0.4 0.2 0.6 0.2 4.7 0.9 0.4 5.3 1.5 0.9 0.3 0.1 4.1 4.3 2.3 0.7 3.6 2.6 53.5 0.8 26.0 0.5 0.2 16.7 1.8 1.8 1.0 90.8 30.8 80.5 33.9 2.5 8.1 43.6 55.9 39.3 88.9 77.3 23.7 77.7 77.4 45.5 22.6 37.0 51.6 49.6 21.0 111.5 81.4 35.6 30.3 34.8 34.4 0.3 53.0 60.2 1.0 2.0 45.0 31.6 16.8 41.1 74.5 58.1 103.9 85.0 17.6 97.3 70.6 43.9 66.1 47.0 65.0 70.3 68.4 25.3 12.4 59.9 68.9 29.9 32.2 30.6 49.7 49.3 109.5 29.4 65.9 73.8 50.1 115.1 73.9 111.5 148.9 22.0 42.9 74.7 1.4 0.1 1.3 1.2 0.0 0.5 0.6 1.8 1.2 0.2 0.7 1.2 1.0 0.4 1.8 0.1 0.3 4.3 0.4 0.5 0.8 0.5 0.8 0.6 0.6 0.9 0.8 0.9 0.7 0.8 1.0 0.5 0.0 0.5 1.3 5.3 5.9 1.9 4.2 1.2 1.2 1.3 2.7 0.9 0.0 3.3 0.0 0.0 21.7 3.6 2.6 0.0 0.8 17.7 2.5 2.5 1.8 0.0 60.8 1.1 0.2 29.7 3.4 5.6 3.0 4.5 18.3 3.3 0.4 14.0 0.0 1.4 3.3 0.0 5.2 3.6 21.4 2.5 3.1 0.0 1.0 0.9 2.0 6.2 0.5 3.6 0.2 0.1 2.2 17.8 0.8 0.9 0.2 0.7 2.3 6.6 0.9 4.2 208.2 40.3 10.6 2.4 4.0 5.0 1.7 9.0 3.8 NUSAP1 "ANKT, BM037, FLJ13421, LNP, PRO0310p1, Q0310, SAPL" ENSG00000137804 "Nucleolar and spindle associated protein 1" Q9BXS6 15 41320794-41381050 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 88.6;lymphoid tissue: 101.5" "Cell type enhanced" "Detected in many" "Erythroid cells: 266.7;Extravillous trophoblasts: 121.2;Granulosa cells: 93.3;Spermatocytes: 99.6" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 15 "basophil: 10.7;T-reg: 7.7" "Group enriched" "Detected in many" 15 "granulocytes: 10.7;T-cells: 7.7" "Low cell line specificity" "Detected in many" "HPA042904, HPA074847" Supported Approved "Nucleoplasm,Nucleoli,Nucleoli fibrillar center" Yes Yes "Cluster 34: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nucleoli, Nucleoli fibrillar center" "HPA042904: AB_2678220, HPA074847: AB_2732269" "unprognostic (1.19e-1)" "unprognostic (9.53e-3)" "unprognostic (1.65e-1)" "unprognostic (8.78e-2)" "unprognostic (3.46e-2)" "unprognostic (2.97e-2)" "unprognostic (1.16e-3)" "unprognostic (1.74e-3)" "unprognostic (1.37e-2)" "unprognostic (4.14e-1)" "prognostic unfavorable (6.27e-4)" "unprognostic (8.49e-3)" "prognostic unfavorable (6.82e-14)" "unprognostic (4.76e-3)" "unprognostic (1.23e-1)" "unprognostic (2.18e-1)" "unprognostic (1.22e-1)" 1.8 14.1 0.2 7.8 0.2 88.6 1.5 0.3 0.4 3.6 0.3 6.1 7.0 1.1 0.1 17.7 1.1 1.0 1.1 0.2 0.2 2.6 5.0 3.8 28.7 0.3 0.4 4.4 1.3 0.0 0.6 6.5 0.3 1.1 8.0 0.1 3.6 0.6 5.4 9.4 7.4 2.7 0.2 7.8 4.5 10.9 0.3 101.5 0.9 0.1 31.5 1.9 6.4 0.3 146.0 38.3 165.1 64.6 3.5 5.9 37.0 107.4 74.6 138.9 130.6 58.4 67.0 63.5 42.5 44.4 99.1 107.6 104.2 46.2 132.4 98.5 62.3 149.6 102.0 50.7 0.2 67.3 57.2 0.9 1.3 69.1 37.3 21.7 72.0 104.2 70.1 237.5 105.7 30.7 147.5 82.2 59.8 139.8 55.0 136.5 156.5 67.5 42.4 29.3 85.7 55.2 129.8 88.5 25.7 46.0 106.2 76.1 33.7 89.9 104.8 101.5 206.2 81.3 145.8 200.5 42.1 163.6 171.2 10.7 0.1 0.5 0.1 0.0 0.0 0.3 0.5 0.5 0.3 0.6 0.0 0.3 0.2 0.4 0.0 0.3 7.7 0.5 0.2 0.2 0.3 0.4 0.2 0.2 0.3 0.4 0.3 0.2 0.3 0.3 1.9 0.0 1.5 1.3 14.2 38.5 10.3 21.2 31.9 0.9 9.9 13.7 1.1 17.2 5.0 0.0 0.0 72.2 13.4 14.4 3.9 2.3 33.2 10.7 11.6 7.3 3.0 266.7 1.4 0.5 121.2 14.6 25.5 21.8 7.0 93.3 10.8 3.9 36.7 0.0 1.5 15.5 24.4 13.8 22.7 14.6 0.3 17.5 3.6 1.9 6.1 1.9 4.1 1.0 1.3 1.5 0.4 1.9 57.2 5.3 2.6 5.4 1.1 1.0 0.0 2.8 12.1 99.6 59.9 69.5 24.9 19.3 22.9 38.8 30.0 10.3 NWD1 ENSG00000188039 "NACHT and WD repeat domain containing 1" Q149M9 19 16719847-16817963 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "choroid plexus: 192.4" "Group enriched" "Detected in some" 4 "Astrocytes: 41.4;Endometrial ciliated cells: 83.9;Respiratory ciliated cells: 92.0" "Cancer enriched" "Detected in many" 6 "prostate cancer: 9.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "U-937: 11.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075476 Approved Nucleoli,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 32: U-937 - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoli, Cytosol" "HPA075476: " "unprognostic (5.29e-3)" "unprognostic (3.08e-2)" "unprognostic (3.05e-2)" "prognostic favorable (2.55e-4)" "unprognostic (2.49e-1)" "unprognostic (4.20e-4)" "unprognostic (6.54e-2)" "unprognostic (5.15e-2)" "unprognostic (2.95e-1)" "unprognostic (1.60e-1)" "unprognostic (7.94e-2)" "unprognostic (1.76e-1)" "unprognostic (9.20e-2)" "unprognostic (1.31e-1)" "unprognostic (5.09e-2)" "unprognostic (3.53e-2)" "unprognostic (3.25e-1)" 0.0 0.0 5.4 0.0 6.2 0.1 0.2 7.6 4.9 1.3 192.4 0.5 0.0 0.2 0.4 0.2 12.6 0.2 0.0 12.2 5.2 0.2 0.0 1.3 0.0 6.2 8.8 0.0 1.5 0.0 0.7 0.0 6.1 6.8 0.1 1.1 1.3 1.8 0.0 0.2 0.0 0.0 3.2 0.0 0.8 0.2 10.1 0.2 0.7 0.0 0.0 0.1 0.0 3.7 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.4 2.4 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.4 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.4 6.2 7.6 4.9 12.2 5.2 6.2 8.8 6.1 3.2 10.1 3.7 0.0 0.0 1.5 41.4 0.3 0.3 1.7 3.5 0.0 0.2 0.5 0.3 0.9 0.0 4.5 0.0 0.0 0.1 0.0 0.4 0.0 0.1 17.9 83.9 0.8 0.3 1.2 0.0 2.4 0.0 0.2 0.3 0.0 3.7 0.0 0.1 0.0 0.0 0.1 0.0 1.4 0.6 2.0 0.0 0.4 3.3 0.6 0.3 0.0 0.0 0.0 8.9 0.0 1.5 1.2 0.2 0.4 0.0 0.0 4.0 0.0 0.1 92.0 0.6 0.0 1.1 1.4 0.0 0.2 0.0 0.1 1.1 0.4 0.0 0.4 1.4 OBP2B "hOBPIIb, LCN14" ENSG00000171102 "Odorant binding protein 2B" Q9NPH6 9 133205277-133209250 "Predicted secreted proteins" "Olfaction, Sensory transduction, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skin 1: 2.7;testis: 10.0" "Group enriched" "Detected in some" 9 "Breast glandular cells: 17.7;Breast myoepithelial cells: 29.1" "Group enriched" "Detected in many" 8 "breast cancer: 7.8;endometrial cancer: 16.2;ovarian cancer: 4.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 35: Glandular cells - Unknown function" "unprognostic (1.40e-1)" "unprognostic (5.70e-2)" "unprognostic (9.45e-3)" "unprognostic (6.65e-2)" "unprognostic (1.04e-1)" "unprognostic (1.30e-1)" "unprognostic (7.03e-2)" "unprognostic (6.82e-6)" "unprognostic (2.00e-2)" "unprognostic (1.12e-1)" "unprognostic (2.53e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.1 0.0 10.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.0 0.0 0.4 0.3 0.0 0.0 0.0 17.7 29.1 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.7 0.0 0.0 0.3 0.0 0.0 2.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 2.5 1.2 0.1 1.8 1.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.1 0.0 0.0 0.0 0.2 1.2 0.1 0.1 OC90 PLA2L ENSG00000253117 "Otoconin 90" Q02509 8 132024216-132059382 "Predicted secreted proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (1.92e-1)" "unprognostic (2.93e-1)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.2 0.1 0.3 0.1 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OCA2 "BEY, BEY1, BEY2, D15S12, EYCL, EYCL2, EYCL3, P" ENSG00000104044 "OCA2 melanosomal transmembrane protein" Q04671 15 27754875-28099315 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Albinism, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "choroid plexus: 28.1" "Cell type enhanced" "Detected in some" "Excitatory neurons: 30.9;Inhibitory neurons: 40.8;Melanocytes: 42.7;Peritubular cells: 14.7" "Cancer enriched" "Detected in many" 17 "melanoma: 19.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "SK-MEL-30: 24.6" "Low region specificity" "Detected in some" HPA036402 Approved "Plasma membrane,Cytosol" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" Cytosol "HPA036402: " "unprognostic (6.07e-3)" "unprognostic (1.97e-2)" "unprognostic (3.25e-1)" "unprognostic (2.82e-2)" "unprognostic (4.60e-4)" "unprognostic (7.11e-2)" "unprognostic (1.10e-1)" "unprognostic (4.12e-2)" "unprognostic (3.47e-2)" "unprognostic (4.95e-2)" "unprognostic (1.96e-2)" "unprognostic (1.60e-2)" "unprognostic (2.20e-6)" "unprognostic (2.61e-1)" "unprognostic (4.21e-1)" "unprognostic (3.28e-2)" "unprognostic (2.28e-2)" 0.3 0.0 1.8 0.1 1.8 0.0 0.3 0.1 1.8 1.2 28.1 0.1 0.0 0.2 0.3 2.2 1.1 0.0 0.3 1.4 1.8 0.3 0.1 0.6 1.8 0.5 0.9 0.3 0.0 0.0 0.8 1.5 0.6 0.6 0.0 0.0 0.8 1.0 0.2 6.4 0.2 0.0 0.0 1.1 0.1 1.9 2.4 0.4 4.2 0.0 0.7 0.2 2.4 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.2 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.5 0.0 0.0 0.5 0.0 0.0 0.1 5.6 0.0 0.0 24.6 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.8 0.1 1.8 1.4 1.8 0.5 0.9 0.6 0.0 2.4 1.0 0.0 0.0 0.0 0.7 0.0 2.0 0.1 0.1 0.6 0.0 0.0 0.4 0.4 0.0 1.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 4.4 5.6 0.2 0.1 0.0 0.0 30.9 0.0 0.1 1.4 0.0 2.8 0.0 2.3 0.0 0.0 0.1 0.0 40.8 0.1 0.0 0.0 0.9 3.0 9.3 0.1 42.7 0.0 0.0 0.0 0.0 2.5 0.8 0.0 1.2 14.7 0.0 0.0 0.0 0.1 2.0 0.0 0.0 1.0 0.8 4.2 4.9 6.1 0.9 0.1 0.1 0.4 0.1 0.2 OLAH "FLJ11106, SAST, THEDC1" ENSG00000152463 "Oleoyl-ACP hydrolase" Q9NV23 10 15032227-15073853 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 9.0;testis: 27.0" "Cell type enriched" "Detected in some" 4 "Early spermatids: 537.8" "Cancer enriched" "Detected in some" 4 "testis cancer: 3.6" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "neutrophil: 2.6" "Lineage enriched" "Detected in single" 5 "granulocytes: 2.6" "Cell line enhanced" "Detected in some" "HSkMC: 3.6;hTCEpi: 4.8;LHCN-M2: 3.6;SK-BR-3: 5.3;SuSa: 2.6;U-266/70: 3.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA037947, HPA037948" Enhanced NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 83: Testis - Spermatogenesis" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 30: Mammary glandular cells - Lactation" "HPA037947: AB_10795028, HPA037948: AB_10805352" "unprognostic (2.01e-1)" "unprognostic (6.12e-2)" "unprognostic (8.20e-3)" "unprognostic (4.04e-3)" "unprognostic (1.92e-1)" "unprognostic (8.09e-2)" "unprognostic (7.12e-2)" "unprognostic (5.12e-2)" "unprognostic (4.55e-1)" "unprognostic (3.74e-2)" "unprognostic (4.70e-1)" "unprognostic (1.69e-1)" "unprognostic (5.22e-10)" "unprognostic (4.55e-2)" "unprognostic (2.09e-1)" "unprognostic (5.11e-2)" "unprognostic (9.78e-2)" 1.5 0.9 1.1 0.2 0.8 1.1 5.5 0.6 1.5 0.8 0.8 0.2 0.1 0.4 0.4 3.0 1.7 1.0 0.2 1.1 0.3 1.1 0.3 1.7 0.3 0.5 0.3 0.2 0.1 0.3 1.0 3.2 0.3 0.3 0.0 0.7 2.7 0.1 0.2 0.7 0.5 0.2 0.2 9.0 0.3 27.0 0.7 0.1 0.4 0.3 0.0 0.2 0.8 1.2 0.0 0.0 0.1 0.2 0.2 0.7 1.2 0.3 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.4 0.1 0.1 0.2 0.1 0.0 0.5 0.0 0.4 3.6 4.8 0.5 0.0 0.0 0.4 0.1 0.2 0.1 3.6 0.0 0.3 0.2 0.2 0.0 0.3 0.4 0.7 0.2 0.0 0.0 0.0 0.1 0.1 5.3 0.0 2.6 0.1 0.1 0.2 0.0 1.8 0.1 0.1 3.1 0.7 0.2 1.1 0.2 0.0 0.8 0.1 0.1 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.1 0.1 2.6 0.4 0.0 0.5 0.2 0.0 1.1 0.8 0.6 1.5 1.1 0.3 0.5 0.3 0.3 0.2 0.7 1.2 0.7 3.2 0.6 0.3 0.1 0.3 0.5 0.0 0.0 0.1 131.3 0.9 0.4 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.0 2.7 537.8 0.1 0.2 0.3 0.0 0.0 0.1 0.0 1.7 0.3 0.0 0.2 0.0 0.1 0.0 0.3 0.1 0.0 0.1 0.0 0.0 2.2 0.3 66.1 4.4 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 8.2 0.0 0.4 0.0 0.0 0.8 0.7 6.6 0.5 1.0 2.8 1.9 0.0 0.3 11.4 0.9 0.1 0.0 0.1 OLIG3 "Bhlhb7, bHLHe20" ENSG00000177468 "Oligodendrocyte transcription factor 3" Q7RTU3 6 137492199-137494394 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "NTERA-2: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA018303, CAB024865" Uncertain NA NA "Cluster 12: NES - Nervous system development" "Cluster 44: Endometrium - Transcription" "CAB024865: , HPA018303: AB_1854796" "unprognostic (1.07e-3)" "unprognostic (1.44e-1)" "unprognostic (2.77e-1)" "unprognostic (2.03e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OSBPL2 "DFNA67, KIAA0772, ORP-2" ENSG00000130703 "Oxysterol binding protein like 2" Q9H1P3 20 62231922-62296213 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Lipid transport, Transport" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 94.6" "Lineage enriched" "Detected in all" 5 "granulocytes: 94.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041127, HPA042659" Uncertain Approved Cytosol NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 27: Brain & Skin - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "HPA041127: AB_10962008, HPA042659: AB_10960683" "unprognostic (1.00e-3)" "unprognostic (7.20e-3)" "unprognostic (1.31e-1)" "unprognostic (6.00e-2)" "unprognostic (1.82e-1)" "unprognostic (1.73e-3)" "unprognostic (3.79e-2)" "unprognostic (9.60e-2)" "unprognostic (6.22e-2)" "unprognostic (1.50e-1)" "unprognostic (1.73e-1)" "unprognostic (6.82e-3)" "prognostic favorable (4.20e-5)" "unprognostic (3.86e-2)" "unprognostic (8.13e-2)" "unprognostic (4.00e-1)" "unprognostic (3.32e-2)" 14.6 15.2 21.1 13.4 21.2 32.9 18.9 38.9 21.4 21.9 20.0 24.3 22.8 14.0 15.8 40.7 15.6 20.0 25.4 16.6 20.3 20.8 18.0 16.2 14.3 23.7 24.0 15.8 39.7 26.4 26.4 13.7 22.3 19.8 22.7 14.5 24.9 18.8 18.0 43.5 21.6 17.4 19.4 24.9 27.9 14.9 29.8 17.2 21.9 11.9 20.4 23.1 29.8 19.4 23.9 17.0 19.6 18.3 19.4 19.1 18.5 14.2 27.9 46.6 32.1 61.0 24.1 11.5 37.1 28.4 41.8 40.7 18.9 42.4 25.7 13.7 17.7 30.6 21.5 31.2 19.0 11.8 26.6 17.7 61.0 20.8 23.3 22.1 19.1 29.4 20.3 21.2 13.5 19.4 17.2 19.8 6.4 43.5 15.0 15.9 23.5 15.3 23.6 48.2 25.6 16.7 25.7 48.2 24.3 25.9 32.1 21.0 13.2 23.2 17.0 24.7 17.3 24.5 37.4 17.5 25.7 8.4 14.9 16.1 9.2 34.5 13.0 11.7 11.4 13.7 10.5 13.7 9.9 10.9 9.5 11.4 94.6 16.8 9.9 7.1 17.5 10.9 21.1 21.2 38.9 21.4 16.6 20.3 23.7 24.0 22.3 19.4 29.8 19.4 27.1 16.0 18.3 17.3 16.5 20.1 24.8 24.4 14.2 18.9 24.7 16.6 61.2 15.7 28.2 11.0 6.2 13.4 21.6 44.5 31.3 22.7 33.0 22.6 12.0 18.1 16.3 24.2 13.9 20.1 14.8 17.8 42.8 34.2 10.8 19.2 12.8 14.1 12.3 18.5 21.7 29.6 22.4 11.1 8.0 17.4 17.4 14.3 8.8 10.3 16.8 18.2 27.8 9.0 15.5 39.8 37.0 13.2 21.9 38.8 30.2 14.1 34.3 15.9 13.1 14.8 13.1 22.8 11.1 25.2 27.8 37.1 18.5 12.0 25.7 58.7 OSBPL6 ORP6 ENSG00000079156 "Oxysterol binding protein like 6" Q9BZF3 2 178194481-178402893 "Plasma proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 33.8;tongue: 20.3" "Cell type enhanced" "Detected in many" "Astrocytes: 281.4;Excitatory neurons: 314.2;Inhibitory neurons: 404.2;Oligodendrocyte precursor cells: 134.2" "Cancer enhanced" "Detected in many" "glioma: 3.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEL: 48.8;hTERT-HME1: 50.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA032131 Enhanced Approved "Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA032131: AB_10670963" "unprognostic (6.22e-2)" "unprognostic (1.53e-1)" "unprognostic (2.47e-1)" "unprognostic (5.95e-3)" "unprognostic (5.26e-2)" "unprognostic (1.40e-2)" "unprognostic (7.55e-2)" "unprognostic (4.81e-2)" "unprognostic (3.32e-1)" "unprognostic (1.03e-1)" "unprognostic (3.03e-3)" "unprognostic (3.49e-2)" "unprognostic (1.15e-5)" "unprognostic (1.11e-2)" "unprognostic (1.30e-1)" "unprognostic (3.73e-4)" "unprognostic (4.44e-6)" 1.3 1.5 4.1 1.0 6.1 0.2 1.7 3.7 16.3 1.1 0.0 1.0 0.7 0.8 0.7 2.4 1.0 1.1 3.8 6.1 8.0 2.7 5.6 4.0 1.1 5.7 6.9 1.4 1.2 0.8 6.7 0.6 5.3 3.1 1.0 8.4 2.2 1.5 33.8 8.7 3.5 1.4 1.7 1.0 0.8 1.3 7.5 1.6 2.3 20.3 0.8 1.0 1.5 8.3 0.0 1.1 8.3 16.9 6.8 7.5 6.3 13.9 7.2 12.0 14.6 1.4 0.2 0.0 0.5 12.9 6.6 0.3 19.6 11.4 20.2 0.2 10.2 48.8 2.9 0.0 4.4 8.0 0.3 5.0 17.6 26.4 50.8 4.3 5.8 6.2 0.9 5.8 15.9 7.0 0.1 0.0 10.0 0.0 10.2 0.0 16.9 3.2 0.9 0.0 6.3 3.8 6.2 1.8 13.7 9.2 2.4 0.1 11.4 13.7 8.5 9.3 16.3 31.8 13.4 0.0 16.3 0.0 6.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.1 4.1 6.1 3.7 16.3 6.1 8.0 5.7 6.9 5.3 1.7 7.5 8.3 0.7 0.0 7.2 281.4 0.0 13.3 2.1 1.3 7.4 59.4 2.1 1.7 15.2 4.3 6.5 0.0 25.0 0.2 0.0 0.1 1.9 0.6 1.0 4.4 1.0 1.7 1.8 0.0 314.2 0.8 4.9 4.3 0.0 0.4 7.0 2.0 0.0 6.2 3.9 1.7 404.2 6.0 4.1 3.5 1.0 1.1 0.0 0.7 5.4 62.8 0.0 10.6 0.0 134.2 10.3 0.2 0.0 1.5 1.5 2.2 9.5 6.2 78.2 6.9 0.0 25.4 5.8 0.1 2.1 6.4 20.9 0.1 0.9 14.5 1.4 0.5 PADI2 "KIAA0994, PDI2" ENSG00000117115 "Peptidyl arginine deiminase 2" Q9Y2J8 1 17066761-17119451 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 240.6;skeletal muscle: 311.8;tongue: 492.3" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 95.9;Distal enterocytes: 178.7;Intestinal goblet cells: 77.3;Oligodendrocytes: 117.1;Paneth cells: 72.3" "Cancer enhanced" "Detected in many" "glioma: 24.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "eosinophil: 43.3;neutrophil: 100.6" "Lineage enriched" "Detected in many" 6 "granulocytes: 100.6" "Cell line enhanced" "Detected in some" "A549: 11.6;RPTEC TERT1: 33.1;SK-BR-3: 50.7;T-47d: 13.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047735 Enhanced NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA047735: AB_2680139" "unprognostic (2.61e-2)" "unprognostic (3.60e-2)" "unprognostic (8.94e-3)" "unprognostic (1.57e-1)" "unprognostic (2.33e-2)" "unprognostic (2.44e-1)" "unprognostic (1.49e-1)" "unprognostic (3.74e-3)" "unprognostic (2.78e-3)" "unprognostic (3.28e-3)" "unprognostic (1.29e-1)" "unprognostic (3.07e-1)" "unprognostic (2.87e-1)" "unprognostic (3.64e-2)" "unprognostic (3.15e-1)" "unprognostic (2.27e-1)" "unprognostic (5.91e-3)" 2.1 0.9 85.9 9.3 161.5 23.7 41.1 164.3 103.9 3.3 33.5 89.8 1.4 0.8 0.6 6.1 2.7 1.6 0.6 82.2 165.1 12.7 0.7 4.4 1.0 205.8 167.0 0.2 1.5 2.1 3.7 1.4 212.0 2.6 92.3 50.5 44.4 1.6 311.8 9.6 8.4 5.8 189.3 13.4 2.2 0.8 144.3 2.1 0.6 492.3 1.3 2.5 1.0 240.6 0.0 11.6 0.1 0.0 0.0 0.0 0.7 0.3 0.0 0.1 0.1 0.1 4.9 0.2 1.5 0.5 0.1 1.6 0.4 0.1 0.3 0.0 0.8 0.5 0.0 0.0 0.0 0.7 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.9 3.8 0.6 1.4 1.6 3.9 0.0 0.0 0.0 0.4 33.1 0.0 2.1 0.2 0.0 50.7 0.0 2.7 13.9 2.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 1.9 0.0 1.3 16.2 43.3 0.0 0.9 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.0 100.6 0.0 0.2 0.4 0.0 6.4 85.9 161.5 164.3 103.9 82.2 165.1 205.8 167.0 212.0 189.3 144.3 240.6 0.2 0.0 1.3 28.4 1.0 0.3 0.4 0.6 0.0 2.2 31.2 32.5 0.4 0.0 3.3 1.8 95.9 0.2 0.7 178.7 11.7 0.6 6.1 0.0 0.0 8.2 3.6 0.0 1.5 0.0 0.5 0.6 0.0 0.1 17.1 0.5 0.7 0.0 7.2 0.0 1.4 77.3 2.0 4.8 25.8 10.3 0.3 9.2 28.4 15.9 33.8 33.6 0.0 13.6 117.1 0.0 72.3 0.7 0.4 0.5 15.0 0.3 0.2 29.6 0.0 5.6 1.3 0.2 0.4 0.0 0.4 0.1 0.4 0.0 51.8 0.2 PBK "CT84, FLJ14385, Nori-3, SPK, TOPK" ENSG00000168078 "PDZ binding kinase" Q96KB5 8 27809624-27838082 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "lymphoid tissue: 22.8;testis: 70.3" "Group enriched" "Detected in many" 5 "Early spermatids: 364.9;Spermatocytes: 436.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 282.8" "Group enriched" "Detected in many" 4 "basal ganglia: 4.7;white matter: 13.9" "Not detected" "Not detected" "HPA005753, HPA050656" Enhanced Supported Approved Cytosol NA Yes "Cluster 48: NK-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "HPA005753: AB_1855018, HPA050656: AB_2681205" "unprognostic (7.17e-2)" "unprognostic (7.21e-3)" "unprognostic (1.04e-3)" "unprognostic (2.77e-2)" "unprognostic (1.50e-1)" "unprognostic (1.27e-1)" "prognostic unfavorable (8.29e-5)" "unprognostic (3.65e-3)" "unprognostic (7.38e-2)" "unprognostic (2.88e-3)" "prognostic unfavorable (6.56e-4)" "unprognostic (1.20e-1)" "prognostic unfavorable (1.18e-12)" "unprognostic (9.61e-2)" "unprognostic (1.86e-1)" "unprognostic (8.30e-2)" "unprognostic (8.68e-2)" 1.1 0.6 0.1 6.6 0.1 9.1 2.3 0.0 0.1 1.1 0.0 8.9 8.4 1.2 0.0 6.6 0.6 0.7 0.2 0.1 0.1 0.4 1.1 0.7 12.8 0.1 0.3 0.2 0.4 0.2 0.0 5.1 0.2 0.4 10.1 0.0 0.9 0.0 0.2 4.8 8.1 2.7 0.1 1.5 3.6 70.3 0.3 22.8 0.5 0.1 12.4 1.6 2.1 0.1 282.8 94.2 94.4 57.9 8.3 15.7 36.9 129.5 63.0 133.2 112.3 33.7 51.2 156.4 43.3 51.7 150.2 76.4 87.6 44.7 145.7 35.8 48.0 35.0 64.6 49.2 0.6 25.7 54.1 4.4 36.0 62.6 32.8 24.3 68.5 75.9 54.3 100.6 160.4 34.5 87.7 29.1 15.6 80.1 80.0 54.4 126.9 41.2 51.2 44.9 36.1 53.2 48.2 56.0 75.0 26.2 58.0 37.3 40.6 85.6 207.3 111.5 141.5 15.4 39.4 70.1 54.0 43.4 188.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.3 0.2 0.1 0.3 0.1 0.2 0.0 0.0 0.0 4.2 8.9 2.8 10.8 0.0 0.0 2.9 2.4 0.5 2.8 2.6 0.0 0.0 29.8 1.3 5.5 0.0 0.6 364.9 2.5 2.2 2.4 0.0 61.7 0.1 0.0 49.3 6.7 6.6 3.5 0.0 13.5 5.7 1.7 5.0 0.0 0.1 9.4 6.1 1.9 1.6 76.8 8.4 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.3 3.0 14.0 2.0 1.5 0.3 0.1 0.0 6.6 0.1 5.8 436.4 38.1 9.4 2.4 6.7 1.9 2.4 18.7 3.8 PCP4 PEP-19 ENSG00000183036 "Purkinje cell protein 4" P48539 21 39867438-39929397 "Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 647.3;seminal vesicle: 1280.1" "Group enriched" "Detected in many" 4 "Bipolar cells: 600.9;Distal tubular cells: 645.6;Horizontal cells: 1398.2;Proximal tubular cells: 941.2" "Cancer enhanced" "Detected in many" "prostate cancer: 41.7;thyroid cancer: 48.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "RPMI-8226: 215.9;T-47d: 64.7" "Low region specificity" "Detected in all" HPA005792 Enhanced Supported Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Nucleoli fibrillar center" "HPA005792: AB_1855086" "unprognostic (6.82e-2)" "prognostic favorable (9.76e-4)" "unprognostic (5.26e-2)" "unprognostic (1.56e-1)" "unprognostic (4.03e-2)" "unprognostic (2.94e-1)" "unprognostic (2.87e-2)" "unprognostic (1.07e-1)" "unprognostic (1.04e-1)" "unprognostic (3.95e-3)" "unprognostic (2.63e-1)" "prognostic favorable (1.85e-7)" "unprognostic (9.00e-2)" "unprognostic (2.99e-3)" "unprognostic (1.10e-1)" "unprognostic (1.07e-2)" 5.2 52.9 197.6 2.0 647.3 0.0 8.4 166.2 202.0 180.9 509.6 135.5 5.1 126.9 365.6 228.2 10.2 4.2 4.6 121.8 175.9 52.1 0.5 0.6 0.2 75.6 299.1 3.5 6.2 19.7 8.8 2.0 70.2 323.4 32.4 385.3 21.3 1280.1 0.6 14.8 6.0 54.6 64.1 2.6 7.1 0.9 491.1 7.9 227.7 0.0 1.0 468.0 128.6 85.5 0.0 0.0 3.1 0.5 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.1 0.0 2.3 1.9 0.0 0.0 0.0 0.0 215.9 0.5 0.0 0.3 0.3 0.0 34.8 0.0 0.2 64.7 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 197.6 647.3 166.2 202.0 121.8 175.9 75.6 299.1 70.2 64.1 491.1 85.5 0.0 0.0 1.5 15.3 2.9 3.1 0.4 0.0 0.0 600.9 0.4 0.4 8.8 2.8 0.0 77.3 62.6 0.3 0.0 0.1 645.6 0.4 1.3 0.0 0.2 5.0 1.2 0.0 71.3 0.2 0.3 1.5 0.0 0.0 0.0 0.4 0.0 0.1 0.2 1398.2 21.5 0.2 0.0 0.0 7.5 0.4 9.6 7.0 21.4 8.4 0.0 68.4 0.0 7.5 11.9 0.8 0.2 0.4 0.0 4.4 0.0 941.2 0.0 200.0 0.0 0.0 77.4 3.4 9.5 0.0 6.0 2.9 2.2 0.5 0.5 1.0 PDE6A "PDEA, RP43" ENSG00000132915 "Phosphodiesterase 6A" P16499 5 149857953-149944793 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Sensory transduction, Vision" Hydrolase "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 68 "retina: 1119.5" "Cell type enriched" "Detected in many" 11 "Rod photoreceptor cells: 2946.4" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in single" 5 "CACO-2: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA016970, HPA074677" Enhanced NA NA "Cluster 11: Basophils - Unknown function" "Cluster 79: Retina - Phototransduction" "Cluster 39: CACO-2 - Unknown function" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA016970: AB_1855125, HPA074677: AB_2732264" "unprognostic (6.85e-2)" "unprognostic (8.84e-2)" "unprognostic (1.70e-2)" "unprognostic (4.11e-2)" "unprognostic (1.12e-2)" "unprognostic (5.72e-2)" "unprognostic (4.39e-3)" "unprognostic (8.83e-2)" "unprognostic (6.54e-2)" "unprognostic (5.91e-3)" "unprognostic (1.77e-2)" "unprognostic (9.21e-2)" "unprognostic (7.57e-5)" "unprognostic (9.93e-2)" "unprognostic (3.08e-1)" "unprognostic (1.31e-1)" "unprognostic (2.26e-2)" 0.1 0.7 0.5 0.2 0.5 0.9 0.2 1.4 0.7 0.1 0.2 1.2 0.2 0.1 16.3 0.9 0.2 0.2 0.2 0.5 0.5 0.1 0.1 0.3 0.1 0.3 0.3 0.2 0.2 0.2 1.7 0.1 0.5 0.3 0.9 1119.5 0.4 0.2 0.3 0.6 0.1 0.1 0.2 0.2 0.2 1.5 0.6 0.0 0.4 0.0 0.2 0.0 0.1 1.2 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.0 2.5 0.2 0.3 0.4 0.0 0.4 0.2 0.0 0.1 0.1 0.1 0.0 0.2 0.4 0.2 0.0 0.2 0.1 0.0 0.3 0.3 0.2 0.2 0.0 0.0 0.1 0.4 0.4 0.1 0.1 0.2 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.3 0.2 0.3 0.0 0.2 0.0 0.1 0.3 0.1 0.4 0.2 0.4 0.1 0.1 0.2 0.1 0.1 0.2 0.2 0.1 1.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.3 0.1 0.1 0.6 0.2 0.1 0.2 0.1 0.0 0.5 0.5 1.4 0.7 0.5 0.5 0.3 0.3 0.5 0.2 0.6 1.2 0.9 0.0 5.8 0.0 0.4 1.1 0.6 0.8 0.0 150.5 0.5 0.4 6.7 0.0 2.8 0.0 244.0 1.1 1.6 14.3 0.0 0.1 18.4 1.5 0.5 11.6 0.0 0.0 1.2 0.2 2.2 1.2 0.0 2.5 3.8 1.9 2.2 0.6 0.3 75.7 0.6 0.4 2.0 1.9 0.4 5.5 1.2 1.5 0.0 0.0 1.4 263.1 5.2 0.5 0.2 0.1 2.8 0.4 0.3 0.4 0.4 0.1 3.2 2946.4 0.0 1.0 1.2 2.3 0.8 5.4 0.6 2.9 1.5 2.2 2.7 0.2 PDZK1 "NHERF3, PDZD1" ENSG00000174827 "PDZ domain containing 1" Q5T2W1 1 145670852-145708148 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "kidney: 595.8" "Group enriched" "Detected in many" 5 "Proximal enterocytes: 280.0;Proximal tubular cells: 1113.8" "Group enriched" "Detected in many" 4 "liver cancer: 27.6;renal cancer: 44.3" "Region enriched" "Detected in many" 7 "cerebellum: 14.7" "Immune cell enriched" "Detected in single" 5 "NK-cell: 4.2" "Lineage enriched" "Detected in single" 5 "NK-cells: 4.2" "Group enriched" "Detected in many" 4 "RPTEC TERT1: 250.0;T-47d: 653.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA005755, HPA006155, CAB008971" Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 6: T47d - Mammary gland" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Vesicles" Cytosol "CAB008971: , HPA005755: AB_1855164, HPA006155: AB_1855163" "unprognostic (4.56e-3)" "unprognostic (3.07e-1)" "unprognostic (8.79e-2)" "unprognostic (4.41e-2)" "unprognostic (9.15e-2)" "unprognostic (2.09e-1)" "unprognostic (2.18e-1)" "unprognostic (3.42e-1)" "unprognostic (2.08e-1)" "unprognostic (3.27e-1)" "unprognostic (2.34e-2)" "unprognostic (9.87e-3)" "prognostic favorable (2.54e-7)" "unprognostic (9.90e-2)" "unprognostic (3.02e-1)" "unprognostic (1.00e-3)" "unprognostic (8.87e-2)" 0.6 3.5 0.7 0.5 0.9 0.6 19.6 14.7 2.0 2.4 1.9 4.7 74.8 0.7 15.8 0.2 1.0 22.0 0.4 1.0 0.5 595.8 128.1 0.3 0.7 1.4 0.8 0.3 16.6 0.0 0.6 0.5 1.8 0.3 8.2 3.0 0.4 0.8 0.3 2.6 124.9 0.8 0.4 0.7 2.8 0.6 0.8 0.3 0.3 0.1 0.2 0.2 0.3 1.5 7.6 1.2 0.8 0.8 0.3 0.4 3.0 1.2 0.3 0.2 1.0 106.6 1.0 0.7 1.3 5.9 0.5 3.4 0.2 0.6 0.6 10.3 2.0 0.9 2.8 45.7 0.0 1.1 0.9 0.3 0.7 0.4 0.2 0.8 0.0 0.4 0.8 1.6 0.8 6.0 0.7 1.4 1.2 1.5 3.6 0.4 7.3 1.6 250.0 0.3 0.6 6.7 1.7 1.8 0.2 6.4 653.8 0.9 0.5 1.3 1.3 0.9 1.1 8.8 1.2 0.6 1.0 0.6 0.5 0.1 0.1 0.0 0.7 0.1 0.2 0.6 0.2 0.8 0.0 0.4 0.2 0.3 0.1 4.2 0.0 0.5 0.0 0.3 0.7 0.9 14.7 2.0 1.0 0.5 1.4 0.8 1.8 0.4 0.8 1.5 0.2 0.0 0.0 2.0 4.1 0.1 0.0 0.1 0.0 0.4 20.2 3.3 0.5 72.9 0.0 57.0 0.0 0.0 0.9 27.4 138.9 1.2 8.6 1.1 0.5 0.4 6.6 0.0 2.8 2.0 0.1 0.5 0.5 4.9 0.0 0.2 1.1 47.9 0.2 0.0 1.9 7.8 0.0 0.9 0.3 9.0 0.0 4.9 0.0 1.9 0.0 0.3 2.1 3.0 0.7 1.5 7.4 0.0 0.0 0.1 280.0 1113.8 0.1 0.5 0.0 0.1 0.3 0.2 0.3 0.0 0.0 0.1 4.1 4.3 6.5 0.1 PECR "HSA250303, SDR29C1, TERP" ENSG00000115425 "Peroxisomal trans-2-enoyl-CoA reductase" Q9BY49 2 215996329-216082955 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 160.2" "Cell type enhanced" "Detected in many" "Hepatocytes: 91.0;Proximal enterocytes: 49.5;Proximal tubular cells: 79.1" "Cancer enhanced" "Detected in all" "liver cancer: 30.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 38.3;RPTEC TERT1: 35.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021593, HPA022539" Enhanced Supported Peroxisomes NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 85: Liver - Metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Peroxisomes "HPA021593: AB_1855177, HPA022539: AB_1855178" "unprognostic (7.97e-2)" "unprognostic (1.08e-1)" "unprognostic (5.72e-2)" "unprognostic (1.32e-3)" "unprognostic (2.90e-1)" "unprognostic (6.40e-2)" "unprognostic (1.16e-3)" "unprognostic (3.56e-2)" "unprognostic (4.03e-2)" "unprognostic (1.11e-1)" "unprognostic (5.01e-3)" "unprognostic (5.61e-2)" "prognostic favorable (1.36e-5)" "unprognostic (6.63e-2)" "unprognostic (1.84e-2)" "unprognostic (7.75e-2)" "unprognostic (6.64e-2)" 25.4 5.4 2.7 2.9 3.1 7.1 10.2 3.8 2.9 4.5 6.0 8.7 26.0 3.3 4.1 3.1 8.1 9.7 2.4 2.7 2.8 33.9 160.2 6.4 3.9 3.2 3.1 4.1 4.8 7.2 3.2 1.0 3.3 5.0 7.5 2.2 5.6 3.4 6.8 4.2 20.1 3.2 2.6 3.0 3.9 0.5 3.0 3.4 16.1 5.2 3.8 2.3 2.3 3.7 6.0 6.6 2.6 0.1 15.7 5.7 3.1 1.4 3.3 3.7 6.3 7.6 17.1 0.1 11.9 3.5 9.2 1.4 7.5 8.7 6.5 9.5 7.7 7.8 3.6 38.3 15.7 2.0 5.1 5.0 6.1 3.9 5.5 5.6 3.8 4.6 3.3 8.6 8.2 4.4 2.4 2.2 4.8 0.1 4.9 5.3 5.0 0.9 35.9 1.0 3.6 5.2 3.6 7.4 15.6 6.2 8.6 6.5 0.0 2.4 2.5 6.0 4.3 9.8 8.9 3.1 5.3 2.8 5.6 1.2 4.2 1.5 6.5 1.6 7.7 4.3 8.8 7.5 1.5 5.7 9.2 6.1 4.5 9.9 2.3 0.2 16.6 4.1 2.7 3.1 3.8 2.9 2.7 2.8 3.2 3.1 3.3 2.6 3.0 3.7 4.3 6.4 13.6 6.5 7.0 3.7 4.7 4.0 3.4 10.8 2.4 2.9 3.7 35.8 3.4 29.5 14.6 3.9 5.9 11.5 13.7 13.2 0.1 10.1 2.7 3.9 7.2 9.4 15.4 3.8 7.3 5.0 7.7 6.3 1.3 2.0 6.8 91.0 9.6 3.3 18.4 8.0 6.1 4.7 3.7 0.3 5.6 5.5 10.6 8.4 27.4 10.1 9.2 8.5 10.6 5.0 17.7 8.2 5.9 2.0 49.5 79.1 13.1 6.4 0.0 6.6 4.4 0.1 1.6 4.9 2.8 1.6 11.4 1.9 14.6 2.7 PEF1 PEF1A ENSG00000162517 "Penta-EF-hand domain containing 1" Q9UBV8 1 31629866-31644896 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 182.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061608 Supported Nucleoplasm,Vesicles,Cytosol NA NA 570000 "Cluster 2: Granulocytes - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Vesicles, Cytosol" "HPA061608: AB_2684567" "unprognostic (2.92e-2)" "prognostic favorable (3.95e-4)" "unprognostic (1.59e-1)" "unprognostic (2.30e-2)" "unprognostic (1.11e-1)" "unprognostic (8.40e-2)" "prognostic unfavorable (2.88e-4)" "unprognostic (5.22e-3)" "unprognostic (1.04e-1)" "unprognostic (2.79e-2)" "unprognostic (1.60e-2)" "unprognostic (2.12e-1)" "unprognostic (1.35e-1)" "unprognostic (8.85e-3)" "unprognostic (2.38e-1)" "unprognostic (1.60e-1)" "unprognostic (2.89e-3)" 57.3 67.1 76.4 28.5 78.6 37.9 56.4 80.1 81.3 56.3 77.8 59.0 31.3 63.3 84.4 62.1 54.6 38.6 63.8 77.9 81.6 69.4 71.3 61.3 38.5 81.9 78.6 50.2 40.9 69.1 52.1 61.4 84.7 59.4 45.1 26.6 39.9 59.1 42.5 85.7 44.0 60.0 79.9 55.9 51.3 40.1 78.9 56.6 110.9 39.3 61.6 61.9 52.2 81.4 56.9 65.0 53.1 41.3 61.2 63.8 51.0 52.8 89.8 124.4 109.0 38.7 83.2 60.2 71.9 118.3 63.9 58.1 103.9 134.5 100.1 76.0 112.6 49.9 49.4 78.6 107.9 49.0 45.3 66.3 152.6 122.0 113.2 79.2 122.2 72.6 52.4 60.6 90.4 67.1 75.6 47.5 74.3 69.7 72.9 72.5 51.7 66.2 98.6 60.8 75.8 43.9 60.2 56.1 81.0 82.9 50.0 35.5 65.7 54.0 46.0 92.7 71.3 38.7 42.2 65.4 67.7 71.8 65.9 147.3 75.6 93.0 90.2 69.4 86.8 70.9 75.5 81.4 77.5 76.4 70.2 70.6 76.2 87.4 67.2 71.4 84.0 104.8 76.4 78.6 80.1 81.3 77.9 81.6 81.9 78.6 84.7 79.9 78.9 81.4 58.2 41.7 37.7 5.9 31.6 36.2 66.6 70.8 29.6 41.2 34.7 36.2 20.4 21.5 35.3 69.9 12.5 160.0 33.9 36.6 113.5 72.0 81.3 17.4 20.0 60.3 44.3 40.0 8.0 61.9 106.1 34.0 21.9 19.8 72.9 34.3 35.3 24.4 61.9 53.8 7.4 49.8 50.8 18.5 21.8 87.5 45.1 27.8 49.8 7.5 81.6 59.6 46.4 6.0 13.8 59.1 44.0 58.6 23.6 65.4 48.9 57.8 23.5 26.5 19.7 25.8 38.8 44.1 44.2 24.6 51.4 182.8 33.6 50.9 39.5 58.3 PERP "dJ496H19.1, KCP1, KRTCAP1, PIGPC1, THW" ENSG00000112378 "P53 apoptosis effector related to PMP22" Q96FX8 6 138088505-138107419 "Predicted membrane proteins" "Apoptosis, Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 782.9;skin 1: 1115.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 3312.8;Squamous epithelial cells: 3451.4;Suprabasal keratinocytes: 5828.3" "Cancer enhanced" "Detected in all" "head and neck cancer: 555.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 39.8" "Lineage enriched" "Detected in many" 4 "granulocytes: 39.8" "Cell line enhanced" "Detected in many" "hTCEpi: 1024.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022269 Enhanced NA NA "Cluster 38: Basophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA022269: AB_1855219" "prognostic unfavorable (5.46e-4)" "unprognostic (2.90e-1)" "unprognostic (1.94e-1)" "unprognostic (5.18e-2)" "unprognostic (2.82e-2)" "unprognostic (1.27e-1)" "unprognostic (6.28e-3)" "prognostic unfavorable (3.73e-4)" "unprognostic (1.92e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (1.05e-5)" "unprognostic (4.02e-2)" "unprognostic (6.05e-2)" "unprognostic (1.13e-1)" "unprognostic (2.70e-1)" "unprognostic (1.94e-1)" "unprognostic (1.51e-2)" 27.1 9.3 7.0 9.9 7.1 1.5 131.0 7.8 8.6 201.6 13.7 40.9 50.2 23.2 47.9 782.9 61.2 37.9 53.9 6.8 8.1 21.9 93.7 27.0 3.3 9.2 7.8 6.4 33.1 40.6 13.1 38.7 8.6 60.7 38.4 8.7 295.9 46.8 5.7 1115.1 52.0 19.8 7.8 1.4 65.1 3.1 9.3 23.3 24.6 16.3 149.4 60.2 426.4 6.3 81.5 80.3 3.7 11.3 60.0 63.1 172.7 115.5 129.8 17.6 12.9 64.8 143.1 1.5 45.5 37.5 144.0 268.4 15.6 207.6 4.5 126.9 64.6 1.5 70.7 69.8 42.6 1.7 1.0 44.3 1024.8 2.2 111.8 91.7 71.3 5.8 2.4 31.3 3.0 53.4 1.5 4.6 34.4 174.6 47.1 1.5 28.6 0.9 108.2 94.0 29.3 3.7 141.2 68.7 59.6 90.7 36.4 18.4 82.6 29.4 12.1 31.7 2.1 11.1 17.4 1.3 23.0 1.5 65.5 39.8 0.0 0.0 4.3 0.0 7.6 2.0 5.3 3.8 0.0 1.0 0.6 2.3 0.3 0.1 0.0 0.0 8.9 1.3 7.0 7.1 7.8 8.6 6.8 8.1 9.2 7.8 8.6 7.8 9.3 6.3 13.9 211.5 84.2 0.7 8.1 3312.8 1415.8 1383.2 1110.4 3.3 371.4 305.0 137.7 260.2 728.5 154.5 16.7 994.5 17.6 374.8 62.6 588.0 2.1 1013.4 78.1 71.8 147.2 13.9 1.2 305.1 990.1 83.8 197.2 777.1 10.8 0.5 21.4 171.3 82.0 3.3 2.1 185.0 736.5 3.8 259.2 2.7 10.5 12.8 350.4 12.2 10.3 29.1 3.1 2.0 0.5 655.0 316.7 2.6 43.2 789.2 355.0 10.6 743.5 28.3 6.6 15.4 82.6 2.4 1.4 3451.4 5828.3 824.0 67.2 73.5 218.6 1546.6 PGAP2 "CWH43-N, FRAG1, MRT17, MRT21" ENSG00000148985 "Post-GPI attachment to proteins 2" Q9UHJ9 11 3797724-3826371 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "GPI-anchor biosynthesis" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "epididymis: 216.2" "Group enriched" "Detected in all" 4 "Cytotrophoblasts: 74.9;Early spermatids: 147.6;Late spermatids: 296.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063099 Approved Approved Microtubules NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" Microtubules "HPA063099: AB_2684940" "unprognostic (1.94e-1)" "unprognostic (1.14e-1)" "unprognostic (2.19e-1)" "unprognostic (3.18e-2)" "unprognostic (5.13e-2)" "unprognostic (6.06e-2)" "prognostic unfavorable (7.49e-4)" "unprognostic (1.74e-1)" "unprognostic (2.51e-2)" "unprognostic (3.07e-1)" "unprognostic (1.11e-1)" "unprognostic (6.44e-2)" "unprognostic (3.85e-2)" "unprognostic (4.66e-3)" "unprognostic (4.13e-2)" "unprognostic (2.17e-2)" "unprognostic (2.67e-2)" 8.9 14.9 16.4 6.4 17.5 9.5 11.5 15.9 18.2 13.7 17.0 13.9 18.4 8.3 216.2 34.9 19.2 7.6 21.7 16.6 16.3 13.9 30.9 16.2 10.4 17.8 16.6 11.2 28.9 17.6 15.1 14.2 17.2 16.7 13.3 9.2 18.4 33.4 11.4 48.0 16.0 7.6 16.3 11.3 14.1 28.5 17.3 13.1 19.4 9.5 13.5 10.9 18.8 20.9 27.1 36.3 17.2 15.8 15.2 28.9 27.3 10.9 9.4 15.6 14.2 31.1 46.6 29.0 12.3 8.0 9.4 44.1 27.6 30.2 15.5 35.5 30.9 17.7 14.7 38.4 10.7 23.0 22.0 22.8 41.9 11.6 39.3 10.2 18.0 38.4 38.4 41.8 16.6 39.9 28.0 19.3 32.4 56.7 21.5 44.0 2.0 27.8 30.0 31.6 22.7 22.5 19.7 52.0 12.3 20.1 43.2 9.6 16.5 9.9 9.2 23.8 6.8 26.2 31.3 21.6 12.9 15.3 19.1 3.0 6.4 5.9 9.1 9.2 11.0 11.4 13.2 11.3 9.7 12.7 17.3 11.8 18.2 10.7 9.2 6.6 13.3 8.8 16.4 17.5 15.9 18.2 16.6 16.3 17.8 16.6 17.2 16.3 17.3 20.9 8.4 12.8 10.6 7.5 10.6 31.7 15.1 23.3 33.6 14.1 19.2 18.0 13.7 11.5 13.0 12.9 22.9 74.9 5.2 11.4 1.9 15.6 147.6 11.7 6.6 9.0 3.0 13.2 15.4 21.3 18.4 7.6 10.2 14.7 8.8 13.4 3.6 14.6 16.0 3.3 19.1 10.5 10.2 5.0 8.0 296.8 8.7 5.5 5.4 4.7 8.9 9.3 8.2 10.6 23.0 14.2 9.3 6.8 12.2 9.1 39.8 10.2 15.2 9.5 6.6 11.0 7.2 17.7 21.6 31.1 28.6 29.3 9.4 11.8 20.1 13.0 PHETA1 "FAM109A, FLJ32356, IPIP27A, SES1" ENSG00000198324 "PH domain containing endocytic trafficking adaptor 1" Q8N4B1 12 111360651-111369121 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Exocrine glandular cells: 32.6;Granulosa cells: 9.6;Hofbauer cells: 10.6;Pancreatic endocrine cells: 33.8;Theca cells: 8.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 3.1" "Group enriched" "Detected in many" 4 "B-cells: 1.0;dendritic cells: 3.1;monocytes: 1.9" "Cell line enhanced" "Detected in many" "Hep G2: 43.5;OE19: 34.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 1: Pancreatic cells - Digestion" "unprognostic (2.26e-1)" "unprognostic (6.88e-2)" "unprognostic (1.66e-1)" "unprognostic (1.05e-1)" "unprognostic (6.02e-2)" "unprognostic (1.15e-3)" "unprognostic (6.18e-3)" "unprognostic (1.11e-1)" "unprognostic (4.00e-2)" "unprognostic (5.51e-2)" "unprognostic (9.42e-2)" "unprognostic (1.03e-1)" "prognostic unfavorable (1.15e-4)" "unprognostic (1.95e-1)" "unprognostic (1.31e-1)" "unprognostic (4.90e-2)" "unprognostic (2.80e-3)" 7.3 17.1 6.3 3.6 5.5 1.6 6.8 4.9 5.8 11.2 4.5 14.9 28.6 9.8 2.2 12.6 7.8 5.2 19.3 5.0 6.5 9.8 19.5 10.9 2.2 7.1 6.2 14.0 29.0 2.9 5.1 2.5 5.9 9.4 5.4 1.1 9.5 3.6 10.2 20.0 27.9 3.5 5.4 23.2 22.7 10.9 7.0 1.2 6.5 4.6 2.0 7.1 8.6 5.4 8.5 7.4 6.2 9.5 8.5 7.4 16.5 5.4 4.7 4.2 2.2 11.7 5.7 0.2 11.5 8.2 5.9 4.6 3.3 3.5 1.8 3.4 7.6 5.7 2.7 43.5 5.0 1.1 7.4 6.1 8.8 6.3 2.0 8.3 6.3 2.8 13.4 0.6 5.2 8.0 1.4 6.8 9.7 34.3 17.6 5.6 4.2 2.5 4.3 4.7 1.4 18.6 8.4 12.8 3.7 5.2 8.7 2.1 7.6 6.2 12.4 7.2 4.2 5.5 5.0 1.0 6.2 3.8 7.1 0.0 1.2 0.2 0.3 1.9 0.4 0.2 0.1 0.1 3.1 1.0 0.0 0.4 0.0 0.3 1.9 0.3 0.0 0.9 6.3 5.5 4.9 5.8 5.0 6.5 7.1 6.2 5.9 5.4 7.0 5.4 2.7 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 5.3 3.2 0.0 0.0 0.0 3.7 0.0 1.3 1.4 0.0 3.9 6.8 0.0 2.8 5.2 1.3 0.0 0.0 0.0 32.6 5.5 1.8 0.0 4.0 0.0 9.6 0.0 0.0 10.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 33.8 0.0 0.0 0.3 0.0 0.0 7.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 1.2 0.2 8.9 0.0 0.0 PIP "GCDFP-15, GCDFP15, GPIP4" ENSG00000159763 "Prolactin induced protein" P12273 7 143132077-143139739 "Plasma proteins, Predicted secreted proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "salivary gland: 16791.8" "Group enriched" "Detected in many" 4 "Breast glandular cells: 1117.6;Breast myoepithelial cells: 324.2;Melanocytes: 403.8" "Cancer enriched" "Detected in many" 70 "breast cancer: 672.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 333 "T-47d: 703.0" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB002661, HPA009177" Enhanced "Secreted in other tissues" NA NA 66000000 "Cluster 37: B-cells - Transcription" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 6: T47d - Mammary gland" "Cluster 35: Glandular cells - Unknown function" "CAB002661: , HPA009177: AB_1845459" "unprognostic (2.80e-1)" "unprognostic (2.15e-1)" "unprognostic (1.08e-3)" "unprognostic (3.01e-2)" "unprognostic (5.93e-2)" "unprognostic (2.25e-2)" "unprognostic (1.54e-1)" "unprognostic (1.05e-1)" "prognostic favorable (5.96e-5)" "unprognostic (3.14e-1)" "unprognostic (3.49e-2)" "unprognostic (5.55e-1)" 9.1 3.6 0.7 0.2 4.8 0.1 3458.7 2.7 2.7 5.6 0.0 0.5 0.0 0.1 2.7 1.3 4.2 0.1 4.8 0.9 4.6 0.5 2.0 6.4 0.8 8.5 4.4 3.8 21.1 0.4 1.9 2.3 6.8 33.3 0.0 0.0 16791.8 3140.5 1.7 189.7 0.6 0.0 3.5 0.6 0.6 0.7 4.6 0.3 0.7 0.0 1.8 0.6 1.5 11.5 0.0 0.0 0.0 0.2 0.0 0.6 0.1 0.0 1.3 0.0 0.0 0.0 0.5 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.2 0.0 0.0 2.1 0.0 0.0 703.0 0.0 0.0 0.1 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 4.8 2.7 2.7 0.9 4.6 8.5 4.4 6.8 3.5 4.6 11.5 6.9 0.0 2.0 0.0 3.6 10.8 6.6 18.8 0.0 0.0 1117.6 324.2 0.1 0.0 48.2 1.8 0.0 0.0 7.0 0.0 0.0 9.3 0.0 0.0 0.0 3.9 0.0 0.0 0.0 2.5 0.0 3.6 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 24.4 0.0 1.6 0.0 0.0 1.5 403.8 0.0 0.0 0.0 0.0 0.0 0.7 2.1 0.0 0.0 0.0 13.1 0.0 0.1 147.1 0.0 0.0 0.0 9.2 0.0 0.0 0.0 1.7 0.0 2.5 0.0 0.0 13.7 PKLR ENSG00000143627 "Pyruvate kinase L/R" P30613 1 155289293-155301438 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 19.6;kidney: 25.1;liver: 92.5" "Cell type enhanced" "Detected in some" "Early spermatids: 9.3;Erythroid cells: 22.1;Hepatocytes: 16.3;Late spermatids: 23.0;Proximal enterocytes: 14.8;Proximal tubular cells: 48.9" "Cancer enriched" "Detected in some" 9 "liver cancer: 56.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 10 "K-562: 107.8" "Region enhanced" "Detected in single" "basal ganglia: 1.6" "Not detected" "Not detected" "HPA006653, CAB034376, CAB034378" Enhanced Approved Cytosol No NA 5200000 "Cluster 85: Liver - Metabolism" "Cluster 1: K-562 - Erythropoiesis" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "CAB034376: AB_2163671, CAB034378: AB_2252321, HPA006653: AB_2667632" "unprognostic (9.16e-2)" "unprognostic (1.22e-1)" "unprognostic (2.22e-1)" "unprognostic (5.98e-2)" "unprognostic (2.62e-1)" "unprognostic (7.86e-4)" "unprognostic (1.53e-2)" "unprognostic (1.08e-1)" "unprognostic (8.79e-2)" "unprognostic (1.89e-1)" "unprognostic (4.07e-1)" "unprognostic (4.53e-2)" "unprognostic (1.96e-2)" "unprognostic (1.40e-1)" "unprognostic (1.02e-1)" "unprognostic (1.32e-1)" "unprognostic (6.21e-3)" 0.0 0.0 0.0 0.0 0.1 19.6 0.0 0.7 0.1 0.0 0.0 0.4 11.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 25.1 92.5 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 1.2 7.2 0.0 0.0 0.1 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 11.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 107.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.1 0.0 0.5 0.2 0.2 0.3 0.0 0.4 0.0 0.1 0.0 0.0 0.7 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.4 1.5 0.0 1.8 0.0 0.0 0.0 0.6 0.0 0.0 9.3 0.2 0.3 0.1 0.0 22.1 1.2 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.7 16.3 0.2 0.0 1.2 0.9 0.0 0.0 0.0 23.0 0.0 0.3 0.0 1.0 0.1 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 14.8 48.9 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.0 PLCXD1 FLJ11323 ENSG00000182378 "Phosphatidylinositol specific phospholipase C X domain containing 1" Q9NUJ7 X 276322-303356 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 34.7;Distal enterocytes: 34.2;Gastric mucus-secreting cells: 33.1;Paneth cells: 40.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "A549: 110.4;HEL: 172.6" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA007721 Approved Approved Cytosol NA Yes "Cluster 51: Monocytes - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 36: HEL - Hemostasis" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA007721: AB_1079630" "unprognostic (2.73e-2)" "unprognostic (5.67e-2)" "unprognostic (4.57e-2)" "prognostic unfavorable (8.10e-4)" "unprognostic (3.80e-2)" "prognostic favorable (2.50e-4)" "unprognostic (1.47e-3)" "unprognostic (7.92e-2)" "unprognostic (1.72e-2)" "unprognostic (4.80e-2)" "unprognostic (7.25e-2)" "unprognostic (1.11e-3)" "prognostic unfavorable (7.82e-14)" "unprognostic (6.01e-2)" "unprognostic (1.95e-1)" "unprognostic (3.59e-2)" "unprognostic (1.78e-1)" 14.7 4.1 4.6 9.4 8.8 32.9 9.7 13.0 19.2 10.0 0.0 8.2 8.6 5.6 1.4 17.5 9.1 8.8 5.6 4.4 0.0 5.7 10.1 7.4 17.3 3.4 1.5 12.8 7.5 3.2 7.7 7.8 4.4 7.5 5.7 6.0 11.4 3.7 8.4 18.7 12.5 2.7 0.5 17.5 26.9 6.7 4.0 8.9 10.4 2.7 9.0 6.1 9.7 13.4 28.4 110.4 25.7 38.8 5.0 3.9 20.4 24.4 2.9 12.8 12.4 40.6 29.1 34.8 17.9 10.7 19.0 8.5 6.3 15.9 6.7 21.2 46.2 172.6 36.1 59.7 15.6 17.4 63.1 20.1 1.9 47.0 4.9 8.6 9.7 57.2 44.0 18.7 9.2 8.2 52.3 24.2 57.8 7.1 19.2 29.1 13.3 53.9 3.9 12.9 25.9 15.0 24.6 14.4 21.1 17.5 27.6 22.0 7.2 17.1 28.2 18.5 26.9 6.3 17.9 86.4 11.0 44.4 18.2 3.7 2.7 5.4 1.9 6.0 2.7 1.6 1.4 2.4 2.0 5.6 1.8 1.9 3.3 1.2 9.0 2.1 3.2 2.3 4.6 8.8 13.0 19.2 4.4 0.0 3.4 1.5 4.4 0.5 4.0 13.4 15.8 9.6 34.7 5.5 4.1 6.9 13.6 3.9 2.2 7.4 4.7 3.6 6.5 10.0 2.8 0.0 2.1 10.1 4.9 34.2 0.0 6.3 0.9 1.6 3.4 6.1 3.0 9.9 5.3 1.8 11.3 6.1 33.1 3.2 3.8 32.1 4.6 6.9 5.5 8.4 6.1 11.2 0.0 7.3 9.8 0.9 2.5 11.9 0.0 5.6 3.7 2.3 9.2 0.5 5.7 18.8 40.9 3.8 2.7 5.3 3.0 1.7 1.3 7.1 13.1 6.5 7.9 8.4 15.9 4.2 8.7 27.0 3.8 2.8 9.4 8.0 PLD1 ENSG00000075651 "Phospholipase D1" Q13393 3 171600404-171810950 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 86.8" "Cell type enriched" "Detected in many" 5 "Oligodendrocytes: 519.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 8.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 57.5;SK-MEL-30: 31.1;TIME: 50.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004527, HPA042396, HPA066938" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 10: Basophils - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles Nucleoplasm "CAB004527: AB_677324, HPA042396: AB_2677977, HPA066938: " "unprognostic (3.23e-1)" "unprognostic (3.27e-1)" "unprognostic (5.82e-2)" "unprognostic (5.13e-2)" "unprognostic (4.58e-1)" "unprognostic (4.76e-2)" "unprognostic (9.03e-2)" "unprognostic (1.46e-1)" "unprognostic (6.23e-2)" "unprognostic (8.02e-2)" "unprognostic (2.06e-2)" "unprognostic (2.95e-2)" "unprognostic (1.23e-1)" "unprognostic (1.29e-1)" "unprognostic (1.16e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (4.76e-6)" 7.8 26.4 9.2 6.6 24.7 7.8 7.5 18.4 13.6 10.4 4.5 14.6 46.9 6.2 2.8 33.0 6.4 86.8 24.4 10.5 14.3 12.0 33.7 4.7 9.1 24.8 22.0 24.2 21.2 1.6 2.3 10.7 23.5 3.4 14.7 0.5 13.8 6.0 2.5 29.2 43.9 4.8 14.7 15.7 8.2 5.0 19.0 4.1 3.7 6.8 10.8 5.1 12.4 41.4 4.5 7.2 3.7 1.4 11.2 12.6 7.7 2.3 9.9 3.5 4.3 1.1 6.4 0.0 17.0 0.9 24.0 15.2 0.6 2.0 5.7 3.6 3.2 4.2 11.5 26.1 4.9 7.3 18.9 4.9 10.9 4.2 2.0 10.0 57.5 1.2 2.8 0.0 0.9 1.3 0.0 6.4 0.8 11.9 5.1 0.2 1.5 0.1 8.9 1.8 0.1 0.1 7.9 4.7 31.1 5.1 9.0 9.7 50.7 1.5 5.7 4.0 2.5 9.6 8.2 0.1 6.7 8.6 1.9 8.3 1.8 2.3 0.3 1.1 2.6 0.0 0.2 0.6 0.6 0.0 0.0 0.1 1.0 2.2 0.4 0.0 0.8 0.6 9.2 24.7 18.4 13.6 10.5 14.3 24.8 22.0 23.5 14.7 19.0 41.4 7.7 0.0 4.7 2.0 0.9 7.1 3.4 11.0 10.8 0.4 4.9 5.6 33.6 57.2 11.1 1.8 0.0 3.0 1.9 37.5 3.9 8.4 13.1 1.0 4.8 7.4 4.2 6.3 8.9 3.4 3.7 15.7 27.0 1.3 27.9 10.4 6.4 15.9 20.0 0.0 12.1 23.6 6.1 13.2 2.4 9.5 10.5 10.2 12.4 98.4 5.4 0.0 1.0 12.5 519.6 2.4 18.3 4.5 3.4 0.7 38.3 48.0 9.9 0.1 19.7 3.8 8.4 6.1 5.3 93.5 34.9 2.3 2.3 12.1 17.8 4.7 PLEK2 ENSG00000100558 "Pleckstrin 2" Q9NYT0 14 67386984-67412167 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 51.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 149.0;Pancreatic endocrine cells: 179.8;Suprabasal keratinocytes: 90.6;Theca cells: 107.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "memory CD4 T-cell: 2.0;naive CD4 T-cell: 3.1" "Lineage enriched" "Detected in single" 7 "T-cells: 3.1" "Cell line enhanced" "Detected in many" "A-431: 91.0;CAPAN-2: 94.4;HBEC3-KT: 177.4;PC-3: 64.1;TIME: 69.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA001208 Enhanced Uncertain Vesicles,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" Vesicles Cytosol "HPA001208: AB_1079631" "unprognostic (4.41e-3)" "unprognostic (3.77e-1)" "unprognostic (1.15e-1)" "unprognostic (6.23e-2)" "unprognostic (6.88e-2)" "unprognostic (3.17e-3)" "unprognostic (1.18e-2)" "prognostic unfavorable (1.58e-4)" "unprognostic (1.97e-1)" "unprognostic (9.21e-3)" "prognostic unfavorable (8.26e-5)" "unprognostic (1.06e-1)" "unprognostic (3.09e-3)" "unprognostic (2.90e-1)" "unprognostic (1.29e-1)" "unprognostic (8.98e-2)" "unprognostic (4.59e-2)" 0.8 51.1 0.3 5.5 0.3 12.7 3.9 0.8 0.6 3.9 0.1 25.1 29.6 1.5 32.4 16.4 1.7 3.9 0.3 0.4 0.2 9.7 29.7 1.6 0.2 0.3 0.2 0.6 7.9 7.0 1.3 1.5 0.3 7.7 28.7 0.1 6.8 4.2 0.3 26.5 32.6 1.3 0.2 0.6 20.6 3.1 0.4 22.9 23.5 0.2 5.5 12.1 7.9 0.4 91.0 13.4 0.0 0.1 0.0 1.0 8.4 17.9 2.7 4.2 5.2 48.8 94.4 0.0 17.3 2.5 0.2 42.4 0.1 177.4 9.6 0.1 0.7 0.0 19.4 0.4 3.8 0.0 0.0 1.9 12.3 4.6 55.4 0.0 14.8 0.0 0.4 0.4 3.0 28.9 0.0 0.2 0.3 57.4 64.1 0.0 0.1 14.0 30.0 2.4 0.7 0.2 17.0 7.9 5.2 0.9 11.6 0.9 69.3 0.0 54.1 0.3 0.4 0.3 0.2 0.3 10.7 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.0 0.3 0.4 0.0 3.1 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.3 0.8 0.6 0.4 0.2 0.3 0.2 0.3 0.2 0.4 0.4 0.1 0.0 1.1 1.0 0.6 149.0 29.0 69.9 37.0 0.0 4.9 6.0 0.5 10.0 11.8 5.5 0.0 1.0 0.0 25.0 3.9 42.1 0.1 2.3 0.2 2.0 8.4 16.0 0.8 46.3 5.5 4.2 37.2 2.2 0.0 24.0 0.0 11.5 6.8 0.0 0.6 68.5 26.4 1.3 57.1 0.3 0.3 7.4 21.4 0.0 5.2 0.0 0.0 0.5 0.3 179.8 23.9 0.0 0.0 15.8 47.9 3.2 4.5 0.0 0.0 0.0 4.6 0.4 2.3 21.2 90.6 1.5 1.3 107.7 54.8 25.5 PLEKHB1 "KPL1, PHR1, PHRET1" ENSG00000021300 "Pleckstrin homology domain containing B1" Q9UF11 11 73646178-73662819 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 1531.3;choroid plexus: 728.4;retina: 758.1" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 344.0;Early spermatids: 145.6;Late spermatids: 184.4;Muller glia cells: 496.6;Rod photoreceptor cells: 460.4" "Cancer enhanced" "Detected in all" "glioma: 59.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 83.7" "Lineage enriched" "Detected in many" 5 "T-cells: 83.7" "Cell line enhanced" "Detected in many" "Hep G2: 77.2;OE19: 53.3;U-266/84: 30.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 46: Photoreceptor cells - Phototransduction" "unprognostic (1.20e-1)" "unprognostic (5.07e-1)" "unprognostic (2.91e-1)" "unprognostic (9.72e-2)" "unprognostic (2.16e-1)" "unprognostic (1.48e-1)" "unprognostic (2.46e-2)" "unprognostic (1.41e-3)" "unprognostic (3.01e-1)" "unprognostic (3.94e-2)" "prognostic favorable (6.02e-4)" "unprognostic (3.59e-1)" "prognostic favorable (1.99e-6)" "unprognostic (2.64e-1)" "unprognostic (7.23e-2)" "unprognostic (4.47e-1)" "unprognostic (7.44e-2)" 2.7 6.7 1011.3 7.7 1362.5 1.3 10.4 1275.8 1156.9 6.9 728.4 52.9 11.6 3.0 15.0 4.7 24.3 10.3 14.7 914.2 1059.3 12.3 2.1 15.2 8.9 1472.5 1259.8 3.0 22.9 88.1 135.2 0.9 1433.2 13.2 9.0 758.1 59.0 8.6 9.4 5.2 19.8 3.0 1263.6 4.2 20.5 20.2 1172.4 5.6 28.8 11.9 7.6 8.2 5.5 1531.3 0.7 2.0 4.8 3.8 2.0 0.6 0.2 0.2 0.1 0.3 0.3 8.5 16.2 0.1 20.0 0.5 0.6 0.4 2.6 0.4 0.4 11.0 12.5 0.0 1.0 77.2 1.2 0.0 0.2 0.7 0.0 0.3 0.0 4.1 0.1 19.4 0.3 10.5 0.3 6.3 5.3 0.3 3.1 53.3 1.0 3.8 0.1 2.6 0.7 1.4 11.8 2.8 0.0 0.3 1.7 3.5 5.6 1.0 0.0 0.0 2.2 0.1 1.6 17.5 30.4 11.3 2.8 0.0 0.8 0.2 0.5 1.1 17.1 0.0 41.5 18.3 41.4 30.6 0.5 7.9 83.7 47.3 0.9 4.3 0.1 0.9 26.9 27.4 1011.3 1362.5 1275.8 1156.9 914.2 1059.3 1472.5 1259.8 1433.2 1263.6 1172.4 1531.3 0.7 6.4 13.5 25.5 5.3 0.4 1.1 1.7 0.6 53.6 19.1 11.8 8.1 25.8 4.5 7.3 344.0 0.5 1.9 0.8 11.7 30.6 145.6 27.4 0.5 3.9 62.8 0.0 1.1 0.8 0.1 2.0 13.7 3.7 11.4 10.4 1.8 0.2 2.7 20.2 0.6 11.2 22.4 0.3 0.3 184.4 2.5 0.9 10.6 7.5 1.6 496.6 6.2 15.6 96.4 2.9 3.9 0.7 1.0 4.0 0.9 13.9 42.8 460.4 0.0 2.5 1.8 2.6 1.7 0.3 0.1 0.1 9.7 0.1 6.5 1.6 PLEKHD1 UPF0639 ENSG00000175985 "Pleckstrin homology and coiled-coil domain containing D1" A6NEE1 14 69484692-69531551 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.1;parathyroid gland: 6.0;retina: 8.8" "Group enriched" "Detected in some" 13 "Bipolar cells: 60.9;Horizontal cells: 230.5" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 13 "plasmacytoid DC: 3.7" "Lineage enriched" "Detected in single" 13 "dendritic cells: 3.7" "Cell line enhanced" "Detected in some" "OE19: 1.1;SK-BR-3: 2.4;T-47d: 2.3;U-266/70: 1.0" "Region enhanced" "Detected in many" "cerebellum: 30.0" "Low region specificity" "Detected in many" HPA051875 Uncertain NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 62: Horizontal cells - Visual perception" "HPA051875: AB_2681648" "unprognostic (8.73e-2)" "unprognostic (4.64e-3)" "unprognostic (3.73e-2)" "unprognostic (4.03e-2)" "unprognostic (7.58e-2)" "unprognostic (3.15e-3)" "unprognostic (1.44e-1)" "unprognostic (1.64e-3)" "unprognostic (3.28e-1)" "unprognostic (1.83e-1)" "unprognostic (4.56e-3)" "unprognostic (1.22e-1)" "unprognostic (5.49e-2)" "unprognostic (8.08e-2)" "unprognostic (2.28e-1)" "unprognostic (2.74e-2)" "unprognostic (1.42e-2)" 0.1 0.2 1.2 0.1 0.5 0.5 0.6 8.1 2.4 0.3 0.0 0.0 0.2 0.1 1.6 0.1 0.1 0.1 0.1 0.3 1.4 1.4 0.0 0.2 0.9 1.4 3.2 0.1 0.2 6.0 0.3 0.1 1.6 0.1 0.0 8.8 1.6 0.3 0.1 1.5 0.1 0.0 0.4 0.2 0.2 1.2 4.5 0.1 2.2 0.0 0.2 0.0 0.0 1.1 0.1 0.1 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.0 0.4 0.1 0.1 0.2 1.1 0.0 0.1 0.0 0.1 0.2 0.2 0.3 0.7 0.0 2.4 0.0 0.0 2.3 0.0 0.0 0.1 0.3 0.1 0.1 1.0 0.2 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 3.7 0.0 0.0 1.2 0.5 8.1 2.4 0.3 1.4 1.4 3.2 1.6 0.4 4.5 1.1 0.5 0.0 7.3 0.3 0.0 0.4 1.8 0.1 0.0 60.9 0.6 0.4 1.3 0.0 2.0 0.0 4.2 0.1 11.2 0.1 3.9 0.1 0.5 0.4 0.2 1.0 0.0 0.0 6.3 0.2 0.1 0.6 0.0 0.6 1.3 0.1 0.4 0.0 0.1 230.5 3.3 0.0 0.0 0.0 0.6 0.1 0.0 1.0 0.0 0.0 0.6 1.7 1.0 0.0 0.1 0.3 0.0 0.0 0.0 1.4 0.2 0.5 0.9 5.9 0.0 1.4 0.6 0.8 0.3 0.0 0.3 0.1 2.3 0.2 0.1 0.7 PLIN1 PLIN ENSG00000166819 "Perilipin 1" O60240 15 89664367-89679427 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 17 "adipose tissue: 956.3;breast: 463.0" "Cell type enriched" "Detected in some" 7 "Hepatocytes: 59.0" "Group enriched" "Detected in many" 5 "breast cancer: 8.4;liver cancer: 2.3;pancreatic cancer: 2.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 171 "ASC diff: 208.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA024299, CAB033821, CAB037333" Enhanced Uncertain Peroxisomes NA NA 22000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" Peroxisomes "CAB033821: AB_2252681, CAB037333: , HPA024299: AB_1855467" "unprognostic (4.62e-2)" "unprognostic (2.22e-1)" "unprognostic (2.13e-1)" "unprognostic (1.67e-1)" "unprognostic (1.90e-1)" "unprognostic (3.51e-3)" "unprognostic (9.89e-3)" "unprognostic (3.54e-1)" "unprognostic (7.01e-2)" "unprognostic (2.13e-2)" "unprognostic (8.00e-3)" "unprognostic (2.28e-3)" "unprognostic (2.62e-6)" "unprognostic (5.56e-2)" "unprognostic (1.22e-1)" "unprognostic (1.63e-1)" "unprognostic (4.85e-2)" 956.3 11.3 12.0 3.5 14.8 0.3 463.0 7.4 10.6 1.4 5.3 9.3 0.5 0.7 0.4 1.3 1.4 6.6 10.4 10.0 10.3 2.7 40.8 0.7 1.7 6.9 11.5 2.1 6.1 0.2 1.3 0.2 7.8 2.6 3.7 0.6 20.8 0.6 9.5 16.0 13.9 1.5 6.6 1.0 5.5 13.2 10.6 2.3 5.3 17.3 0.1 7.9 3.1 8.2 0.0 0.2 0.2 0.0 208.2 0.7 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.3 0.0 0.0 0.2 0.0 0.1 0.0 0.5 0.7 0.5 0.1 0.7 0.2 0.0 0.2 0.6 0.7 0.0 0.1 0.3 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.5 0.0 0.1 0.0 0.1 0.3 0.2 0.1 0.3 1.2 0.1 0.5 0.1 0.1 0.0 0.1 0.2 0.2 0.1 0.4 0.3 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 14.8 7.4 10.6 10.0 10.3 6.9 11.5 7.8 6.6 10.6 8.2 2.6 0.0 0.0 4.2 0.2 0.1 0.3 0.1 0.0 0.3 0.7 3.0 1.1 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.2 7.5 0.1 0.2 0.2 0.0 0.0 0.5 0.2 0.0 0.3 0.0 0.2 0.0 0.1 1.1 59.0 0.0 0.0 0.3 0.3 0.0 1.0 0.3 7.5 0.9 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.7 0.2 1.3 0.0 0.0 0.6 0.3 0.1 0.1 0.1 0.0 1.3 1.3 4.8 0.2 0.0 0.4 0.0 0.1 0.1 0.5 0.9 PLIN5 "LSDA5, LSDP5, MLDP, OXPAT" ENSG00000214456 "Perilipin 5" Q00G26 19 4522531-4535224 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 202.0;skeletal muscle: 149.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 47.1;Astrocytes: 53.8;Cardiomyocytes: 39.8;Hepatic stellate cells: 42.1;Hepatocytes: 140.5" "Cancer enhanced" "Detected in many" "liver cancer: 9.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "neutrophil: 13.9" "Lineage enriched" "Detected in single" 20 "granulocytes: 13.9" "Cell line enhanced" "Detected in some" "AN3-CA: 2.3;BEWO: 3.2;RT4: 3.1;SH-SY5Y: 2.8;T-47d: 6.3" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA077050 Supported "Vesicles,Lipid droplets" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 6: T47d - Mammary gland" "Cluster 15: Hepatocytes - Hemostasis" "Vesicles, Lipid droplets" "HPA077050: " "prognostic favorable (7.68e-4)" "unprognostic (1.01e-1)" "unprognostic (4.22e-2)" "prognostic unfavorable (8.56e-4)" "unprognostic (1.24e-2)" "unprognostic (6.06e-3)" "prognostic favorable (2.81e-4)" "unprognostic (1.11e-2)" "unprognostic (4.67e-2)" "unprognostic (1.05e-1)" "unprognostic (1.63e-1)" "unprognostic (1.54e-1)" "prognostic favorable (1.97e-4)" "unprognostic (3.18e-1)" "unprognostic (1.40e-1)" "unprognostic (8.28e-3)" "prognostic favorable (2.16e-4)" 41.9 6.4 10.8 3.5 11.2 5.2 29.3 6.9 9.6 7.5 12.8 5.4 1.5 2.7 3.9 3.4 12.6 2.0 62.7 8.5 8.1 30.1 202.0 9.3 0.5 8.4 9.2 90.8 112.2 1.5 18.9 0.2 6.9 17.6 0.6 0.9 61.0 3.9 149.2 8.0 5.3 0.5 6.8 8.2 58.9 3.3 9.4 0.4 9.8 24.7 1.0 11.2 2.7 6.4 0.2 0.1 0.5 2.3 1.7 0.1 3.2 0.1 0.1 0.1 0.0 0.2 0.5 0.1 0.7 0.1 0.1 0.2 0.0 0.0 0.0 0.3 0.1 0.1 0.8 1.1 0.4 0.3 0.4 0.4 0.0 0.0 0.0 0.2 0.2 0.1 0.7 0.2 0.1 0.6 0.1 0.4 0.4 0.3 0.3 0.1 0.1 2.1 0.2 3.1 0.3 2.8 0.2 0.4 0.0 0.2 6.3 0.4 0.3 0.3 0.3 0.2 0.2 0.3 0.1 0.1 0.2 0.6 0.1 1.9 0.4 0.8 0.3 0.3 0.2 0.3 0.2 0.2 0.1 0.4 0.3 0.3 13.9 0.6 0.3 0.3 0.1 0.1 10.8 11.2 6.9 9.6 8.5 8.1 8.4 9.2 6.9 6.8 9.4 6.4 6.0 9.6 47.1 53.8 1.6 0.5 18.4 2.3 4.0 1.2 9.2 1.9 39.8 35.8 11.5 1.8 0.0 0.4 0.1 11.9 9.8 8.7 1.5 20.8 1.4 7.4 0.0 2.7 1.1 12.3 0.5 1.3 16.3 5.1 3.8 18.7 42.1 140.5 0.5 0.0 1.8 6.9 4.1 6.9 0.5 0.3 0.3 2.5 0.0 5.6 0.1 8.1 0.0 11.1 2.0 4.8 1.3 2.6 0.5 6.6 0.5 11.1 10.4 1.2 13.1 25.8 1.8 6.2 6.6 0.5 1.0 1.4 1.1 20.5 8.8 11.5 PLK1 PLK ENSG00000166851 "Polo like kinase 1" P53350 16 23677656-23690367 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 32.0;lymphoid tissue: 43.9;testis: 33.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 32.3;Early spermatids: 123.7;Erythroid cells: 38.3;Extravillous trophoblasts: 55.9;Spermatocytes: 79.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "T-reg: 5.6" "Lineage enriched" "Detected in many" 5 "T-cells: 5.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA051638, HPA053229" Approved NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "HPA051638: AB_2681561, HPA053229: AB_2682084" "unprognostic (7.21e-3)" "unprognostic (1.77e-1)" "unprognostic (1.98e-3)" "unprognostic (4.97e-3)" "unprognostic (9.56e-2)" "unprognostic (5.12e-2)" "prognostic unfavorable (2.70e-7)" "prognostic unfavorable (2.28e-5)" "unprognostic (2.55e-2)" "unprognostic (1.89e-1)" "prognostic unfavorable (4.12e-4)" "unprognostic (1.24e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.33e-1)" "unprognostic (8.10e-2)" "unprognostic (1.19e-1)" "unprognostic (1.26e-2)" 1.4 1.5 2.3 13.4 2.3 32.0 1.5 2.5 3.2 2.3 2.0 9.6 10.4 1.2 0.4 13.9 1.0 1.4 1.0 2.3 2.1 1.4 1.9 1.9 27.8 2.3 2.3 1.3 1.1 0.2 1.2 6.4 2.2 1.2 10.1 1.2 2.4 0.3 1.0 5.7 9.2 4.0 2.0 9.1 6.2 33.1 2.5 43.9 0.9 0.4 30.0 2.8 4.0 2.8 199.9 207.5 166.2 90.9 5.2 11.7 92.8 111.0 74.5 172.5 127.0 184.3 131.0 99.1 56.3 76.5 90.1 112.8 229.5 93.5 206.1 139.5 128.0 125.2 163.4 257.1 1.7 147.5 133.7 4.8 5.2 124.7 125.2 21.6 127.9 127.5 200.7 133.9 134.8 187.8 139.8 151.4 189.5 82.1 103.5 217.2 111.7 160.0 49.3 43.9 94.3 65.3 126.8 88.9 55.8 94.4 114.4 92.1 65.1 82.7 102.7 79.9 194.1 93.2 156.8 173.6 69.3 127.7 137.2 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.8 0.3 0.3 0.0 0.0 0.0 0.4 0.9 0.0 0.0 5.6 1.4 2.3 2.3 2.5 3.2 2.3 2.1 2.3 2.3 2.2 2.0 2.5 2.8 0.6 3.2 0.0 3.3 7.6 1.3 1.2 6.5 0.0 1.4 1.7 2.3 0.6 0.0 1.4 0.0 4.2 32.3 0.4 5.5 0.0 0.8 123.7 3.4 1.3 2.5 0.0 38.3 3.1 0.8 55.9 4.7 10.2 1.8 1.3 19.9 3.3 1.1 20.8 0.0 2.3 7.3 4.1 6.9 3.2 13.9 1.2 7.2 0.0 2.8 0.4 1.1 0.0 1.5 2.3 1.2 0.3 0.7 23.0 2.0 1.5 0.1 1.3 1.3 0.0 2.3 6.1 79.5 13.5 12.2 1.8 3.8 2.5 1.2 17.9 2.0 PLP2 "A4, A4-LSB, MGC126187" ENSG00000102007 "Proteolipid protein 2" Q04941 X 49171898-49175235 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 496.5;Exocrine glandular cells: 496.6;Pancreatic endocrine cells: 550.1;Suprabasal keratinocytes: 504.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042415 Approved NA NA 250000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA042415: AB_10796907" "unprognostic (1.40e-1)" "unprognostic (6.67e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (3.32e-5)" "unprognostic (3.79e-2)" "unprognostic (1.30e-1)" "unprognostic (1.04e-3)" "unprognostic (4.14e-2)" "unprognostic (2.58e-2)" "unprognostic (9.99e-2)" "unprognostic (1.19e-2)" "unprognostic (1.66e-1)" "prognostic unfavorable (5.55e-10)" "unprognostic (1.66e-1)" "unprognostic (1.25e-1)" "unprognostic (1.29e-2)" "unprognostic (2.30e-1)" 105.1 195.8 17.3 87.6 17.6 358.6 99.8 19.8 21.3 173.6 27.0 164.1 71.0 162.0 42.7 381.7 124.4 53.2 121.0 17.3 24.4 61.3 36.6 118.6 59.9 22.7 21.9 110.3 250.8 37.5 97.4 60.8 20.4 97.8 130.5 6.2 119.3 104.7 99.0 390.6 96.2 156.6 20.2 79.1 114.6 23.3 21.7 77.9 46.8 53.3 148.0 182.8 264.3 19.7 539.1 312.8 0.4 1.0 131.6 388.9 1.6 278.2 223.5 339.9 255.4 115.2 248.4 193.5 68.1 209.2 340.7 444.1 260.5 517.4 214.5 490.2 104.2 71.4 421.1 3.1 210.0 136.0 304.2 174.7 505.6 443.5 516.5 317.6 260.9 63.0 55.1 239.6 249.2 346.0 14.9 346.2 3.3 263.6 456.2 48.9 300.1 563.8 464.6 355.1 69.4 120.6 394.4 155.6 244.4 2.6 340.6 77.0 293.7 194.4 185.4 344.6 472.4 102.2 100.6 50.9 461.3 359.7 464.4 486.8 287.7 148.7 59.9 99.8 100.7 226.4 214.3 112.8 298.5 144.8 107.8 93.4 320.0 70.5 63.7 694.2 265.8 235.8 17.3 17.6 19.8 21.3 17.3 24.4 22.7 21.9 20.4 20.2 21.7 19.7 49.3 73.7 38.2 1.0 160.8 439.7 306.0 496.5 167.9 0.4 67.8 115.4 33.3 57.2 101.9 80.9 0.0 2.7 232.0 134.6 21.5 379.6 16.4 71.8 27.8 63.7 111.7 43.1 0.6 496.6 27.2 110.4 71.9 51.1 88.7 15.4 55.3 12.8 157.5 0.0 0.7 254.9 138.4 130.3 210.5 20.3 169.9 133.3 224.1 4.7 146.4 18.9 35.0 0.0 0.6 550.1 200.3 60.9 148.5 219.5 141.8 9.4 92.9 1.1 124.9 76.1 128.7 4.2 1.4 401.0 504.9 6.4 162.7 29.6 285.2 334.1 PLPP2 "LPP2, PAP-2c, PPAP2C" ENSG00000141934 "Phospholipid phosphatase 2" O43688 19 281040-291403 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cholangiocytes: 204.5;Ductal cells: 352.1;Proximal enterocytes: 209.8;Rod photoreceptor cells: 234.9;Urothelial cells: 205.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 3.2;MAIT T-cell: 6.6" "Lineage enriched" "Detected in single" 41 "T-cells: 6.6" "Cell line enhanced" "Detected in many" "A549: 144.1;CAPAN-2: 154.6;OE19: 255.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055540, HPA058428" Uncertain Supported "Plasma membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane" "HPA055540: AB_2682839, HPA058428: " "prognostic unfavorable (4.55e-4)" "unprognostic (8.91e-3)" "unprognostic (1.06e-1)" "prognostic favorable (3.21e-8)" "unprognostic (2.95e-1)" "unprognostic (1.36e-1)" "unprognostic (3.83e-3)" "unprognostic (5.48e-2)" "unprognostic (1.59e-1)" "unprognostic (5.67e-2)" "unprognostic (1.18e-3)" "unprognostic (3.85e-1)" "unprognostic (3.53e-3)" "unprognostic (1.06e-2)" "unprognostic (1.71e-1)" "unprognostic (1.30e-3)" "unprognostic (1.36e-3)" 4.8 13.2 37.7 8.5 61.6 0.0 36.9 57.1 50.0 63.4 26.2 40.5 62.7 16.8 8.4 27.2 81.8 52.4 1.7 38.8 43.5 11.5 3.7 8.3 1.4 57.3 53.6 2.7 37.3 19.5 11.8 3.6 56.2 31.7 32.1 29.6 105.7 32.9 0.6 53.2 51.0 6.4 44.8 4.7 50.3 7.6 49.2 5.2 5.7 0.5 6.0 36.5 14.2 83.9 85.5 144.1 2.1 0.1 0.0 0.3 0.2 8.2 0.0 25.3 18.9 41.7 154.6 0.0 88.3 11.9 0.1 45.3 0.0 17.6 11.1 0.8 2.6 0.0 55.9 0.0 28.6 0.0 5.5 5.2 7.6 12.7 16.7 53.4 4.2 0.0 0.7 0.1 0.0 98.5 0.4 0.1 61.5 255.8 0.0 0.0 0.0 2.4 62.1 13.7 17.4 40.9 23.3 38.3 60.3 5.8 50.0 2.5 4.5 55.7 36.5 0.5 61.9 0.8 101.7 70.4 15.5 0.0 46.9 0.0 0.0 0.0 3.2 0.0 6.6 0.0 1.3 1.6 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.3 37.7 61.6 57.1 50.0 38.8 43.5 57.3 53.6 56.2 44.8 49.2 83.9 17.0 6.4 7.5 0.0 1.5 0.0 134.2 0.0 8.0 19.7 137.1 149.9 0.0 204.5 35.3 22.0 10.4 0.5 2.7 77.0 3.9 352.1 0.3 115.2 9.2 15.2 8.5 0.0 0.0 139.5 15.1 3.0 91.3 90.1 1.3 0.0 0.0 0.5 0.9 16.8 0.0 38.8 0.0 1.0 0.0 1.6 0.0 1.9 0.0 0.0 2.6 21.7 0.0 0.0 0.0 128.8 85.2 0.0 1.6 97.4 209.8 1.4 91.1 234.9 0.0 0.8 2.7 0.6 35.1 20.3 0.0 0.8 3.5 0.1 87.2 205.8 PM20D1 "Cps1, FLJ32569" ENSG00000162877 "Peptidase M20 domain containing 1" Q6GTS8 1 205828025-205850132 "Enzymes, Predicted secreted proteins" "Hydrolase, Lyase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "pancreas: 78.0;skin 1: 33.8" "Cell type enhanced" "Detected in some" "Exocrine glandular cells: 20.9;Gastric mucus-secreting cells: 7.1;Proximal tubular cells: 7.1" "Cancer enriched" "Detected in some" 32 "urothelial cancer: 30.2" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "T-reg: 2.2" "Lineage enriched" "Detected in single" 6 "T-cells: 2.2" "Cell line enriched" "Detected in single" 9 "Karpas-707: 1.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Secreted to digestive system" NA NA 3300000 "Cluster 35: T-regs - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 2: Karpas-707 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (1.16e-1)" "unprognostic (1.95e-1)" "unprognostic (1.30e-1)" "unprognostic (4.07e-2)" "unprognostic (4.83e-1)" "unprognostic (4.08e-3)" "unprognostic (1.17e-3)" "unprognostic (3.11e-1)" "unprognostic (1.20e-1)" "unprognostic (5.50e-2)" "unprognostic (5.81e-2)" "unprognostic (4.57e-2)" "unprognostic (7.79e-3)" "unprognostic (9.77e-2)" "unprognostic (1.45e-1)" "unprognostic (2.48e-1)" "unprognostic (1.68e-2)" 0.8 0.0 0.2 0.1 0.2 0.0 1.2 0.0 0.3 0.1 1.2 0.1 0.1 0.1 0.5 0.0 0.4 0.0 0.3 0.2 0.3 6.3 0.2 0.2 1.1 0.3 0.3 0.3 78.0 0.0 0.0 0.1 0.3 0.0 0.1 0.3 0.0 0.0 0.0 33.8 0.1 0.0 0.2 1.0 2.9 0.0 0.3 0.1 0.1 0.0 0.4 2.2 0.1 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.4 0.3 0.0 0.5 0.1 0.4 1.3 0.0 0.1 0.1 0.4 0.0 0.0 0.1 0.0 2.2 0.3 0.2 0.2 0.0 0.3 0.2 0.3 0.3 0.3 0.3 0.2 0.3 0.3 0.8 0.0 0.0 1.6 1.1 0.0 0.0 0.0 0.6 0.5 0.0 0.0 1.5 0.0 0.0 0.0 2.1 0.0 0.9 0.1 0.0 0.1 0.0 0.1 0.1 0.3 0.0 0.4 3.2 20.9 0.3 0.5 7.1 0.0 0.0 0.0 0.7 0.3 0.1 0.0 3.5 0.2 0.0 1.3 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 1.0 1.5 1.5 0.6 0.0 0.0 1.8 0.2 0.0 7.1 0.0 0.8 0.0 0.2 0.2 0.1 0.1 0.0 0.1 0.0 0.9 2.4 0.0 0.1 PMEL "D12S53E, gp100, Pmel17, SI, SIL, SILV" ENSG00000185664 "Premelanosome protein" P40967 12 55954105-55973317 "Predicted intracellular proteins, Predicted membrane proteins" "Melanin biosynthesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "cervix: 80.5;endometrium 1: 32.2;skin 1: 115.2" "Cell type enriched" "Detected in many" 32 "Melanocytes: 1472.7" "Cancer enriched" "Detected in many" 500 "melanoma: 2481.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 68 "SK-MEL-30: 8590.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA031649 Enhanced Supported "Endoplasmic reticulum,Golgi apparatus" "Intracellular and membrane" NA NA 11000000 "Cluster 6: Non-specific - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 48: Smooth muscle cells - ECM organization" "Endoplasmic reticulum" "Golgi apparatus" "HPA031649: AB_2673976" "unprognostic (4.63e-1)" "unprognostic (8.93e-2)" "unprognostic (1.53e-1)" "unprognostic (1.60e-1)" "unprognostic (5.90e-2)" "unprognostic (6.46e-2)" "unprognostic (1.94e-1)" "unprognostic (1.46e-3)" "unprognostic (6.44e-2)" "unprognostic (1.21e-1)" "unprognostic (5.12e-2)" "unprognostic (3.98e-1)" "prognostic favorable (3.70e-4)" "unprognostic (2.86e-2)" "unprognostic (1.54e-1)" "unprognostic (7.60e-2)" "unprognostic (1.04e-1)" 3.3 0.8 0.2 0.8 0.2 1.8 8.3 0.7 0.5 80.5 0.3 1.3 1.6 32.2 1.5 0.7 1.2 1.6 0.6 0.3 0.0 2.1 5.0 0.9 5.6 0.0 0.4 4.3 2.3 1.7 0.7 2.8 0.1 0.9 1.2 0.4 3.5 0.8 0.3 115.2 2.1 3.5 0.0 0.5 1.1 4.8 0.0 0.7 1.1 0.2 2.2 1.3 4.0 0.3 14.8 1.1 5.6 0.2 83.6 0.6 126.2 0.9 0.8 1.9 2.0 12.8 6.0 2.6 6.1 0.8 0.3 2.5 0.6 1.0 1.6 3.0 2.1 2.4 2.5 0.7 0.3 1.0 1.4 0.5 1.0 1.2 0.6 1.3 1.0 1.1 0.5 1.8 0.5 2.7 0.4 1.0 17.1 2.8 0.3 1.6 3.5 1.5 1.4 2.7 0.5 2.6 0.3 2.5 8590.9 4.6 4.4 8.8 1.4 0.9 6.5 0.7 7.9 2.1 10.4 3.2 1.0 2.7 0.3 0.0 0.3 0.1 0.0 0.0 0.4 0.3 0.1 0.0 0.0 0.1 0.2 0.0 0.4 0.0 0.0 0.4 0.0 0.1 0.2 0.2 0.7 0.5 0.3 0.0 0.0 0.4 0.1 0.0 0.0 0.3 0.8 0.0 0.5 0.0 0.1 45.9 0.8 1.1 2.8 0.0 1.0 0.9 0.4 1.5 2.2 0.0 0.0 12.1 0.0 1.5 0.0 2.1 8.0 0.7 0.2 1.2 0.0 0.8 0.1 2.3 12.4 1.6 1.1 0.5 0.0 11.1 0.0 2.9 1.7 0.0 0.1 1.6 0.0 0.3 14.6 5.3 12.2 0.6 1472.7 1.0 0.6 0.2 0.0 0.0 0.1 1.0 0.6 0.7 1.2 0.5 2.4 2.8 1.0 0.0 0.0 0.2 1.7 3.9 2.6 1.0 10.2 24.9 0.4 1.3 1.6 0.4 PMVK "HUMPMKI, PMK, PMKA" ENSG00000163344 "Phosphomevalonate kinase" Q15126 1 154924740-154936719 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" "Kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 266.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029900 Approved NA NA 15000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 47: Cytotrophoblasts - Unknown function" "HPA029900: AB_10601390" "unprognostic (2.52e-1)" "unprognostic (3.68e-2)" "unprognostic (1.25e-2)" "unprognostic (1.32e-1)" "unprognostic (2.31e-1)" "unprognostic (1.81e-2)" "unprognostic (8.13e-2)" "unprognostic (5.47e-2)" "unprognostic (8.22e-2)" "prognostic favorable (9.70e-4)" "unprognostic (1.41e-1)" "unprognostic (8.76e-2)" "prognostic favorable (4.96e-4)" "unprognostic (2.07e-1)" "unprognostic (1.67e-1)" "unprognostic (1.78e-1)" "unprognostic (2.10e-1)" 39.9 56.4 99.0 29.8 100.1 15.3 35.0 97.9 108.9 33.4 95.0 39.9 45.9 25.9 17.7 77.7 37.2 17.2 63.1 93.9 96.4 53.8 91.9 30.1 34.6 98.6 97.4 35.8 41.6 58.2 60.3 23.7 96.0 32.4 22.2 19.8 34.0 27.1 79.1 69.2 44.2 27.7 96.4 45.7 40.5 26.6 102.3 27.9 31.5 47.4 36.8 31.9 37.9 99.8 51.8 72.9 46.7 72.5 43.6 30.9 48.5 40.5 29.3 38.9 37.0 30.6 101.0 75.1 75.9 49.3 40.5 49.4 65.3 63.9 17.8 103.3 28.9 34.1 104.1 29.0 40.0 51.4 29.3 36.3 58.7 70.2 49.6 19.5 40.0 65.9 36.8 221.7 41.3 108.3 40.8 51.0 41.0 121.7 95.0 60.3 29.8 171.1 66.1 38.4 37.7 91.1 44.1 75.7 51.9 35.0 146.7 91.1 32.7 35.8 29.2 84.4 62.1 174.0 153.2 131.8 58.9 83.9 46.7 28.0 80.9 91.8 68.2 205.6 110.1 114.8 93.1 70.6 93.6 111.1 59.1 59.1 6.9 59.7 219.4 96.5 134.3 80.0 99.0 100.1 97.9 108.9 93.9 96.4 98.6 97.4 96.0 96.4 102.3 99.8 22.7 57.7 37.5 9.4 42.2 69.8 105.9 95.8 51.8 38.5 67.1 68.3 57.3 78.6 42.2 53.3 8.4 235.7 31.5 65.0 266.1 69.6 9.0 45.0 28.5 29.8 66.4 35.6 5.1 71.3 108.1 45.1 46.9 44.2 22.2 49.8 39.3 146.9 141.0 37.0 7.0 78.9 67.1 67.9 49.5 13.5 42.6 47.8 65.8 3.7 49.5 119.1 41.2 8.0 11.8 61.7 61.7 47.8 58.8 53.7 219.3 246.1 22.1 27.4 32.9 46.0 48.4 51.3 51.3 81.0 90.5 227.7 45.1 162.6 79.9 76.2 PNLDC1 "dJ195P10.2, FLJ40240" ENSG00000146453 "PARN like, ribonuclease domain containing 1" Q8NA58 6 159800249-159820704 "Enzymes, Predicted membrane proteins" "Nonsense-mediated mRNA decay" "Exonuclease, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 10.2;testis: 8.1" "Cell type enhanced" "Detected in some" "Early spermatids: 19.9;Late spermatids: 13.6;Spermatocytes: 14.3;Spermatogonia: 13.3" "Cancer enhanced" "Detected in many" "testis cancer: 4.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA052026 Uncertain NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "HPA052026: AB_2681699" "unprognostic (1.58e-1)" "unprognostic (3.88e-2)" "unprognostic (1.01e-2)" "unprognostic (2.39e-3)" "unprognostic (8.47e-3)" "unprognostic (3.55e-2)" "unprognostic (2.04e-1)" "unprognostic (4.24e-1)" "unprognostic (1.01e-1)" "unprognostic (5.37e-2)" "unprognostic (4.19e-1)" "unprognostic (9.98e-2)" "unprognostic (2.69e-9)" "unprognostic (1.14e-2)" "unprognostic (2.25e-1)" "unprognostic (1.69e-1)" "unprognostic (2.24e-1)" 0.2 0.2 2.1 0.1 3.7 0.1 0.5 2.5 10.2 0.1 1.6 0.3 0.0 0.1 0.0 0.2 1.9 0.0 0.2 2.2 2.0 0.2 0.5 0.2 0.4 1.9 1.9 0.4 1.7 0.0 0.3 0.0 3.0 0.3 0.0 0.1 0.1 0.0 0.1 1.1 0.1 0.0 1.8 0.4 0.2 8.1 2.3 0.2 0.2 0.0 0.2 0.2 0.2 2.7 0.0 0.1 0.0 0.4 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.2 0.0 0.2 0.0 0.2 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 2.1 3.7 2.5 10.2 2.2 2.0 1.9 1.9 3.0 1.8 2.3 2.7 0.1 0.0 0.0 0.3 0.2 0.3 0.0 0.3 0.0 0.0 0.3 0.5 0.3 4.3 0.2 0.0 0.0 0.0 0.1 0.1 0.0 3.8 19.9 2.1 0.1 0.1 0.0 0.0 1.5 0.9 0.0 0.2 0.0 0.1 4.5 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.8 13.6 0.3 0.1 0.0 3.7 0.0 0.0 0.0 0.5 1.3 1.3 0.0 0.0 0.0 0.1 0.0 0.9 2.7 0.0 0.0 0.5 0.2 14.3 13.3 0.0 0.0 0.0 0.1 0.0 0.0 0.2 PNPLA5 "dJ388M5.4, GS2L" ENSG00000100341 "Patatin like phospholipase domain containing 5" Q7Z6Z6 22 43879678-43892013 "Enzymes, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.4;epididymis: 1.7;skin 1: 3.1" "Cell type enhanced" "Detected in some" "Excitatory neurons: 3.2;Inhibitory neurons: 2.1;Late spermatids: 2.1" "Cancer enriched" "Detected in single" 4 "thyroid cancer: 0.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NTERA-2: 1.4;RPMI-8226: 2.7" "Not detected" "Not detected" "HPA050409, HPA054211" Uncertain NA NA "Cluster 34: Basophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 31: Spermatids - Spermatogenesis" "HPA050409: AB_2681118, HPA054211: AB_2682418" "unprognostic (6.69e-5)" "unprognostic (3.53e-1)" "unprognostic (1.28e-1)" "unprognostic (1.27e-2)" "unprognostic (3.33e-3)" "unprognostic (1.05e-1)" "unprognostic (1.50e-1)" "unprognostic (4.31e-2)" 0.0 0.0 0.8 0.1 3.4 0.3 0.3 0.2 2.3 0.0 0.0 0.0 0.0 0.1 1.7 0.0 0.2 0.1 0.0 1.4 0.5 0.0 0.9 0.0 0.0 1.2 0.6 0.0 0.0 0.0 0.9 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 3.1 0.0 0.0 0.1 0.1 0.0 0.1 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.2 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.1 1.4 0.0 0.0 0.0 0.1 2.7 0.0 0.0 0.9 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.8 3.4 0.2 2.3 1.4 0.5 1.2 0.6 0.4 0.1 0.6 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 POLQ POLH ENSG00000051341 "DNA polymerase theta" O75417 3 121431427-121546641 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-directed DNA polymerase, Nucleotidyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.0;lymphoid tissue: 4.5" "Cell type enhanced" "Detected in many" "Erythroid cells: 16.4;Excitatory neurons: 9.5;Granulosa cells: 12.6;Inhibitory neurons: 7.8;Plasma cells: 12.2" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebellum: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebellum: 2.5" HPA053359 Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Golgi apparatus, Cytosol" "HPA053359: " "unprognostic (1.59e-1)" "unprognostic (4.18e-2)" "unprognostic (2.66e-2)" "prognostic unfavorable (5.46e-5)" "unprognostic (2.70e-1)" "unprognostic (6.23e-3)" "unprognostic (3.09e-5)" "unprognostic (8.55e-3)" "unprognostic (1.09e-4)" "unprognostic (2.86e-1)" "unprognostic (5.59e-5)" "unprognostic (2.06e-3)" "unprognostic (0.00e+0)" "prognostic favorable (1.04e-4)" "unprognostic (1.76e-1)" "unprognostic (6.01e-2)" "unprognostic (5.76e-2)" 0.1 0.2 0.0 1.6 0.1 6.0 0.4 1.0 0.2 0.2 0.0 1.2 1.2 0.2 0.0 2.0 0.0 0.1 0.2 0.2 0.0 0.0 0.1 0.2 2.8 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.1 2.0 0.0 0.3 0.0 0.0 1.4 0.9 0.4 0.0 0.8 0.5 2.2 0.0 4.5 0.0 0.0 2.3 0.3 0.5 0.0 18.2 12.1 10.2 7.2 0.9 1.2 9.2 8.5 3.2 9.7 12.9 9.8 6.6 21.5 3.7 4.6 11.7 14.0 12.2 5.4 16.4 6.3 6.7 13.8 8.0 6.1 0.1 15.1 12.1 0.2 0.4 8.9 5.4 1.7 4.9 7.9 9.3 15.9 10.3 7.1 13.7 8.8 9.7 5.5 5.9 11.4 12.2 7.6 3.1 10.3 5.5 5.0 9.8 5.2 3.4 8.8 4.8 14.8 3.8 8.6 11.2 3.4 11.1 8.0 6.9 21.8 4.1 11.0 6.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 1.6 0.7 0.9 0.5 0.6 0.0 0.9 0.6 0.6 1.6 0.0 2.0 0.0 0.0 3.1 0.6 1.6 0.0 0.1 0.4 0.9 1.0 0.5 0.0 16.4 9.5 0.0 3.3 1.2 4.6 1.0 0.0 12.6 0.0 0.2 2.3 0.0 7.8 1.6 2.0 1.3 1.2 0.7 0.3 1.7 0.0 1.0 0.6 0.4 0.0 1.5 1.3 0.2 1.2 0.0 12.2 0.5 0.2 0.1 2.4 0.2 0.0 0.1 1.0 6.8 3.4 4.9 0.1 0.3 1.8 0.9 3.2 0.8 POU2F3 "Epoc-1, OCT11, PLA-1, Skn-1a" ENSG00000137709 "POU class 2 homeobox 3" Q9UKI9 11 120236640-120319945 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skin 1: 48.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 20.9;Pancreatic endocrine cells: 20.8;Suprabasal keratinocytes: 37.6;Urothelial cells: 14.2" "Cancer enhanced" "Detected in many" "ovarian cancer: 3.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 1.4;CAPAN-2: 3.6;EFO-21: 1.3;SK-BR-3: 2.5;T-47d: 3.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA019652, HPA073468" Enhanced Approved "Nucleoplasm,Nucleoli,Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 61: Skin - Cornification" "Cluster 6: T47d - Mammary gland" "Cluster 16: Pancreatic endocrine cells - Mixed function" Nucleoplasm "Nucleoli, Nuclear bodies, Plasma membrane, Cytosol" "HPA019652: AB_1855585, HPA073468: " "unprognostic (1.75e-1)" "unprognostic (2.12e-2)" "unprognostic (6.37e-2)" "unprognostic (2.41e-4)" "unprognostic (2.60e-1)" "unprognostic (4.46e-3)" "unprognostic (8.56e-3)" "unprognostic (9.34e-2)" "unprognostic (3.45e-2)" "unprognostic (1.12e-1)" "unprognostic (1.40e-3)" "unprognostic (2.08e-1)" "unprognostic (1.27e-2)" "unprognostic (9.69e-3)" "unprognostic (1.70e-1)" "prognostic favorable (8.14e-4)" "unprognostic (1.45e-1)" 0.1 0.1 0.2 0.1 0.1 0.2 2.0 0.3 0.4 0.8 0.0 0.6 0.9 0.0 1.7 1.3 0.5 0.7 0.1 0.1 0.1 0.3 0.1 1.0 0.2 0.1 0.1 0.1 0.2 6.3 0.4 0.3 0.1 0.6 0.2 0.1 1.1 2.0 0.2 48.0 0.7 0.3 0.0 0.2 0.7 0.1 0.1 0.2 0.7 0.0 0.5 0.4 2.1 0.3 1.4 0.0 0.0 0.1 0.0 0.0 0.4 0.2 0.3 0.0 0.0 0.0 3.6 0.1 1.3 0.0 0.0 0.6 0.0 0.2 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.2 0.0 0.3 0.0 0.0 0.0 0.0 1.1 0.2 0.0 0.0 2.5 0.0 0.3 3.9 0.1 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.3 0.4 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.3 0.2 0.0 8.2 0.3 0.0 20.9 10.6 5.0 1.8 0.0 3.0 1.5 0.8 0.0 3.9 11.0 0.0 1.5 0.1 0.9 0.0 5.3 2.2 1.3 0.7 0.3 3.0 0.0 0.4 1.3 0.4 0.6 10.2 4.8 0.0 0.0 0.0 0.3 0.1 0.0 0.5 0.2 8.2 0.0 2.2 5.5 0.0 0.1 5.4 0.0 0.0 0.4 0.0 0.0 0.5 20.8 1.1 0.0 0.0 5.0 0.4 0.1 1.8 0.0 0.0 0.0 0.4 0.0 0.1 7.0 37.6 7.9 0.5 0.2 0.6 14.2 PPP1R14C "CPI17-like, KEPI, NY-BR-81" ENSG00000198729 "Protein phosphatase 1 regulatory inhibitor subunit 14C" Q8TAE6 6 150143044-150250392 "Predicted intracellular proteins" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 75.5;skeletal muscle: 66.5;skin 1: 97.2;thyroid gland: 58.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 280.2;Cardiomyocytes: 79.5;Skeletal myocytes: 80.9;Suprabasal keratinocytes: 336.6" "Cancer enhanced" "Detected in many" "thyroid cancer: 53.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 40.7;HBEC3-KT: 86.1;HEK 293: 36.2;hTCEpi: 103.0;hTERT-HME1: 41.1;RPTEC TERT1: 35.5;SK-BR-3: 37.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB044667, HPA047907" Approved NA NA "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 28: Keratinocytes - Keratinization" "CAB044667: , HPA047907: " "unprognostic (1.81e-3)" "unprognostic (7.65e-2)" "unprognostic (4.25e-3)" "unprognostic (6.92e-2)" "unprognostic (3.96e-3)" "unprognostic (2.20e-2)" "unprognostic (3.81e-3)" "unprognostic (1.55e-1)" "unprognostic (6.63e-2)" "unprognostic (5.13e-2)" "unprognostic (4.50e-2)" "unprognostic (1.18e-1)" "unprognostic (2.86e-2)" "unprognostic (2.14e-1)" "unprognostic (1.98e-1)" "unprognostic (7.49e-3)" "unprognostic (6.77e-2)" 0.4 0.2 5.1 1.4 6.6 0.2 6.0 5.9 8.0 10.2 6.0 12.5 10.4 1.4 0.9 18.4 16.0 0.1 75.5 7.8 5.0 9.5 0.0 12.3 0.3 5.6 5.4 0.1 0.7 5.1 1.7 3.4 5.6 1.3 8.6 0.6 3.2 0.2 66.5 97.2 2.7 0.9 4.4 0.1 0.8 6.7 5.0 0.5 58.7 8.5 5.8 0.5 22.0 5.0 27.9 0.1 11.7 0.1 0.1 0.6 0.0 3.7 0.0 0.0 0.1 1.3 3.8 0.7 8.0 5.3 1.8 40.7 6.1 86.1 0.0 0.0 36.2 0.3 0.0 0.0 0.0 0.0 1.1 0.0 103.0 0.2 41.1 0.0 0.0 0.5 23.6 0.0 0.0 3.8 0.0 0.0 0.4 0.0 0.2 0.7 0.0 0.0 35.5 1.5 6.2 0.0 0.6 37.7 2.2 0.7 0.2 1.9 0.0 0.1 20.4 32.5 9.5 0.0 0.0 0.0 14.2 16.1 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 6.6 5.9 8.0 7.8 5.0 5.6 5.4 5.6 4.4 5.0 5.0 0.3 19.2 41.1 1.3 0.5 280.2 17.9 19.6 12.0 1.1 6.5 4.3 79.5 0.0 17.1 14.7 0.0 0.1 0.4 24.5 1.9 3.8 0.2 37.9 0.6 3.0 28.2 0.0 28.0 0.2 0.1 6.7 0.0 5.1 1.3 4.1 0.0 0.0 3.0 1.7 13.3 3.1 14.2 0.0 19.7 1.6 0.0 0.6 30.2 2.8 1.1 0.0 0.0 37.2 2.5 12.8 41.5 0.4 0.0 16.6 5.0 38.6 61.5 0.5 0.0 80.9 4.3 0.5 1.8 14.7 336.6 1.9 1.4 0.5 8.7 1.9 PPP1R1B "DARPP-32, FLJ20940" ENSG00000131771 "Protein phosphatase 1 regulatory inhibitor subunit 1B" Q9UD71 17 39626740-39636626 "Metabolic proteins, Predicted intracellular proteins" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 711.8;choroid plexus: 506.6;intestine: 211.4;salivary gland: 366.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 144.6;Distal tubular cells: 121.3;Intestinal goblet cells: 305.7;Melanocytes: 135.2;Paneth cells: 132.3;Undifferentiated cells: 423.7;Urothelial cells: 171.5" "Cancer enhanced" "Detected in many" "colorectal cancer: 94.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 11 "eosinophil: 1.0" "Lineage enriched" "Detected in single" 11 "granulocytes: 1.0" "Cell line enhanced" "Detected in some" "ASC diff: 7.6;CAPAN-2: 12.6;HSkMC: 31.7;OE19: 15.6;SCLC-21H: 27.4" "Region enriched" "Detected in all" 8 "basal ganglia: 1243.8" "Region enriched" "Detected in all" 26 "basal ganglia: 1534.8" "CAB004026, HPA048630, HPA061142" Approved Approved NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB004026: AB_2169007, HPA048630: AB_2680468, HPA061142: AB_2684438" "unprognostic (2.71e-1)" "unprognostic (4.09e-2)" "unprognostic (6.91e-3)" "unprognostic (2.42e-1)" "unprognostic (3.01e-1)" "unprognostic (7.69e-2)" "unprognostic (6.00e-3)" "unprognostic (2.76e-2)" "unprognostic (1.75e-2)" "unprognostic (6.13e-2)" "unprognostic (6.07e-2)" "unprognostic (2.04e-1)" "unprognostic (1.27e-1)" "unprognostic (2.67e-2)" "unprognostic (2.50e-2)" "unprognostic (2.52e-3)" "unprognostic (1.55e-1)" 93.8 30.2 280.9 19.8 711.8 0.4 74.0 262.7 312.7 20.0 506.6 211.4 83.4 4.4 5.5 4.8 28.4 2.0 3.5 251.7 244.0 29.1 0.5 15.3 0.1 319.6 275.5 11.3 75.7 0.5 15.0 0.0 232.4 62.7 203.4 6.2 366.9 89.7 0.9 56.3 68.7 10.8 243.3 0.1 39.9 15.8 317.9 0.2 0.6 0.0 0.3 18.9 11.4 249.6 0.0 0.0 0.0 0.0 7.6 4.4 0.2 0.0 0.0 0.0 0.0 0.0 12.6 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.9 15.6 0.9 0.0 0.0 0.6 0.0 0.0 27.4 0.6 0.0 1.5 0.0 2.4 0.6 1.1 0.0 0.0 1.8 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 280.9 711.8 262.7 312.7 251.7 244.0 319.6 275.5 232.4 243.3 317.9 249.6 1.0 0.0 34.7 33.3 1.3 1.3 117.1 0.4 0.6 0.6 93.5 84.3 1.1 0.0 0.2 1.8 0.0 0.0 2.4 144.6 121.3 28.7 0.8 46.6 0.9 1.6 96.7 0.0 5.3 3.3 0.0 2.8 13.3 3.2 4.5 0.0 4.2 0.0 0.2 0.0 1.6 305.7 2.0 0.0 0.8 3.2 34.5 1.2 135.2 0.0 0.0 29.8 0.0 1.0 0.5 0.8 132.3 5.7 0.0 84.3 40.4 0.7 0.1 1.3 0.0 1.2 1.7 0.9 3.7 1.2 0.4 0.0 1.9 0.0 423.7 171.5 PRR11 FLJ11029 ENSG00000068489 "Proline rich 11" Q96HE9 17 59155732-59206709 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 18.1;lymphoid tissue: 20.6" "Cell type enhanced" "Detected in many" "Erythroid cells: 26.3;Extravillous trophoblasts: 22.3;Granulosa cells: 14.4;Kupffer cells: 18.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 9.5" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA023923, HPA052376" Uncertain Approved "Endoplasmic reticulum" Yes Yes "Cluster 14: Monocytes - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Endoplasmic reticulum" "HPA023923: AB_1855783, HPA052376: AB_2681803" "unprognostic (1.74e-2)" "unprognostic (1.02e-1)" "unprognostic (1.30e-2)" "prognostic unfavorable (1.90e-4)" "unprognostic (2.15e-1)" "unprognostic (3.03e-2)" "prognostic unfavorable (1.35e-7)" "prognostic unfavorable (1.79e-4)" "unprognostic (7.22e-3)" "unprognostic (2.00e-2)" "prognostic unfavorable (6.18e-4)" "unprognostic (2.80e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.56e-2)" "unprognostic (5.21e-2)" "unprognostic (1.84e-1)" "unprognostic (1.55e-3)" 1.3 0.7 1.8 6.5 2.0 18.1 1.8 4.3 2.7 1.2 1.1 4.6 6.5 1.7 0.5 3.8 1.4 1.4 1.0 2.0 1.3 0.6 1.4 2.3 10.3 2.3 1.5 1.4 0.5 0.3 0.0 4.3 2.2 0.8 5.6 1.7 0.6 0.7 1.2 3.1 5.0 3.6 1.1 3.3 2.4 1.8 2.3 20.6 1.3 0.4 12.0 2.0 0.6 3.7 105.3 56.9 84.5 24.8 2.4 16.0 31.7 66.7 41.9 69.1 54.2 68.4 78.7 80.2 65.9 52.7 56.2 40.7 67.0 73.9 145.0 99.3 39.1 86.4 58.8 50.3 0.6 88.7 32.5 4.0 5.3 81.9 109.0 17.1 77.2 57.9 48.6 76.7 72.8 95.2 80.7 26.1 31.9 52.0 82.5 67.3 135.7 45.9 20.0 32.4 34.5 45.4 61.7 18.4 29.2 38.0 54.4 34.1 57.8 146.4 157.3 73.5 117.8 48.8 108.2 73.6 34.5 47.4 150.1 1.7 2.1 2.3 0.6 4.0 0.2 1.1 0.5 0.7 2.6 0.6 0.3 0.5 2.1 0.5 9.5 1.1 1.4 0.8 1.8 2.0 4.3 2.7 2.0 1.3 2.3 1.5 2.2 1.1 2.3 3.7 4.5 0.0 1.7 3.3 3.1 1.9 2.0 1.5 0.0 2.0 0.8 1.5 2.0 1.5 1.6 0.0 0.0 6.2 1.4 2.0 0.0 0.4 0.9 1.4 1.9 3.6 4.9 26.3 1.6 0.5 22.3 2.9 2.6 2.2 2.5 14.4 4.2 0.3 7.8 1.7 1.8 5.0 0.0 18.6 6.3 0.4 0.9 7.8 1.8 2.8 8.4 0.9 4.1 2.0 3.4 0.9 0.7 2.2 9.7 1.1 0.5 0.5 0.6 3.2 0.0 2.9 3.3 2.6 5.1 5.5 1.3 2.1 3.3 1.3 8.4 1.7 PSAPL1 ENSG00000178597 "Prosaposin like 1" Q6NUJ1 4 7430285-7434930 "Predicted secreted proteins" "Lipid metabolism, Sphingolipid metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "skin 1: 98.5;stomach 1: 38.6" "Cell type enriched" "Detected in some" 13 "Gastric mucus-secreting cells: 41.8" "Group enriched" "Detected in some" 5 "head and neck cancer: 0.7;melanoma: 2.5;pancreatic cancer: 2.0;stomach cancer: 3.0;urothelial cancer: 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "CACO-2: 16.6;OE19: 32.2;RPMI-8226: 24.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA038013, HPA038482" Approved Enhanced Cytosol "Secreted - unknown location" NA NA 31000 "Cluster 61: Skin - Cornification" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" Cytosol "HPA038013: AB_10673652, HPA038482: AB_2676037" "unprognostic (2.64e-2)" "unprognostic (2.40e-1)" "unprognostic (9.33e-2)" "unprognostic (2.40e-1)" "unprognostic (2.61e-1)" "unprognostic (7.90e-3)" "unprognostic (2.52e-1)" "unprognostic (2.08e-2)" "unprognostic (2.75e-1)" "unprognostic (2.63e-3)" 0.3 0.0 0.0 0.0 0.3 0.0 4.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 98.5 0.0 0.0 0.0 0.0 38.6 3.4 0.1 0.2 0.0 0.0 3.1 0.0 0.2 0.7 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 16.6 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.2 0.0 0.0 0.0 24.7 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.7 0.0 0.0 0.0 0.3 0.2 0.1 0.0 1.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 41.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 PSCA ENSG00000167653 "Prostate stem cell antigen" O43653 8 142670308-142682725 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "stomach 1: 3019.3" "Cell type enriched" "Detected in many" 4 "Gastric mucus-secreting cells: 5332.3" "Cancer enriched" "Detected in many" 6 "urothelial cancer: 785.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 22.4;HeLa: 45.7;OE19: 17.6;RT4: 61.7" "Not detected" "Not detected" "Region enriched" "Detected in many" 8 "spinal cord: 38.2" "HPA030783, HPA056418" Approved Supported "Plasma membrane" NA NA 18000 "Cluster 4: Stomach - Digestion" "Cluster 15: RT4 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" "HPA030783: AB_2673611, HPA056418: AB_2683123" "unprognostic (1.21e-3)" "unprognostic (1.76e-3)" "unprognostic (3.20e-1)" "unprognostic (2.24e-1)" "unprognostic (1.77e-2)" "unprognostic (7.57e-2)" "unprognostic (1.93e-2)" "unprognostic (7.81e-3)" "unprognostic (8.25e-3)" "unprognostic (2.13e-1)" "prognostic unfavorable (5.60e-5)" "unprognostic (6.82e-2)" "unprognostic (2.38e-3)" "unprognostic (4.93e-2)" "unprognostic (2.68e-1)" "unprognostic (3.07e-1)" "unprognostic (1.06e-3)" 4.8 0.4 0.5 0.5 0.6 0.2 1.9 0.3 0.9 67.8 0.2 7.8 4.0 0.4 0.6 334.0 7.9 10.0 0.4 0.6 0.2 5.8 0.7 6.3 0.1 0.5 0.3 0.6 3.2 0.0 0.6 2.4 0.4 230.6 4.8 0.0 23.5 1.9 0.3 11.1 2.5 0.1 0.2 0.4 3019.3 1.4 0.5 0.4 0.4 0.0 15.0 629.0 167.7 0.5 10.7 0.7 0.0 0.0 2.1 6.8 10.6 4.9 1.1 2.1 1.8 0.1 22.4 0.0 0.4 0.4 8.1 2.1 0.0 0.4 1.3 0.6 0.0 0.0 45.7 0.0 0.1 0.0 1.5 6.0 7.8 4.6 0.0 0.6 0.0 0.0 0.0 0.0 1.7 5.8 1.7 0.6 1.2 17.6 1.2 0.7 0.0 0.9 1.0 61.7 0.2 0.5 5.1 15.6 3.5 0.3 0.2 0.2 1.0 1.5 1.7 2.7 0.0 1.9 0.1 0.0 2.9 0.8 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.3 0.9 0.6 0.2 0.5 0.3 0.4 0.2 0.5 0.5 0.2 3.2 1.5 1.6 7.7 0.9 26.0 120.0 0.0 0.0 3.9 2.7 1.2 71.4 894.2 1.8 0.0 2.3 0.0 1.9 7.9 3.2 0.3 1.3 0.1 1.1 275.1 0.0 0.3 1.2 5.0 3.3 5332.3 0.3 0.0 0.3 0.0 0.0 0.6 0.0 0.2 12.9 179.0 0.6 1.0 0.4 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 57.1 0.2 0.0 13.4 238.7 0.3 0.4 994.9 0.0 0.0 0.0 48.9 0.0 0.5 13.1 1.3 28.5 4.6 0.0 0.9 1241.5 PSG7 ENSG00000221878 "Pregnancy specific beta-1-glycoprotein 7" Q13046 19 42924132-42937207 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "placenta: 4.1;skin 1: 1.2" "Cell type enriched" "Detected in some" 95 "Syncytiotrophoblasts: 162.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 1.6;fHDF/TERT166: 1.1;HBF TERT88: 2.3;U-2197: 1.8" HPA046327 Supported "Secreted in female reproductive system" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 18: U-2197 - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "HPA046327: AB_2679624" 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.3 0.1 0.5 0.0 0.0 0.0 0.0 1.1 0.3 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 162.0 0.0 0.0 0.0 0.0 PTPRQ DFNB84 ENSG00000139304 "Protein tyrosine phosphatase receptor type Q" 12 80402178-80680273 "Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "kidney: 7.1;urinary bladder: 4.1" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 16.0;Club cells: 4.4;Early spermatids: 10.9;Excitatory neurons: 11.2;Late spermatids: 4.6" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 4.9;BJ: 3.9;HBF TERT88: 2.6;RH-30: 2.9;RT4: 3.4;SiHa: 1.9;U-2197: 3.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA053245 Uncertain Approved Cytosol No NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 18: U-2197 - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA053245: AB_2682087" "unprognostic (9.10e-2)" "unprognostic (1.63e-1)" "unprognostic (1.15e-1)" "unprognostic (3.30e-2)" "unprognostic (1.37e-1)" "unprognostic (1.93e-2)" "unprognostic (1.04e-2)" "unprognostic (1.46e-1)" "unprognostic (1.80e-2)" "unprognostic (1.78e-1)" "unprognostic (4.47e-11)" "unprognostic (8.51e-3)" "unprognostic (1.47e-1)" "unprognostic (1.73e-2)" "unprognostic (2.66e-2)" 3.2 0.0 0.3 0.0 2.0 0.0 0.4 0.0 0.7 0.5 0.0 0.1 0.0 0.0 1.9 0.1 1.6 0.2 1.1 0.2 0.4 7.1 0.0 2.3 0.9 1.0 0.7 0.3 0.3 0.1 0.1 0.1 0.6 0.6 0.0 0.8 0.1 0.1 0.2 0.1 0.0 0.0 0.8 0.0 0.1 2.7 0.3 0.2 2.9 0.0 0.3 4.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 4.9 0.0 3.9 0.8 1.2 0.7 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.5 0.0 0.5 0.1 0.3 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 3.4 0.0 0.0 1.9 0.0 0.0 0.1 0.2 0.0 0.0 0.3 0.1 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.0 0.0 0.7 0.2 0.4 1.0 0.7 0.6 0.8 0.3 0.0 0.0 16.0 1.1 2.0 0.0 0.0 1.9 0.3 0.0 0.1 0.0 0.0 3.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.9 0.0 0.0 0.0 0.0 0.0 11.2 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 4.6 0.0 0.1 0.0 0.0 0.0 0.9 0.0 2.5 1.3 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.5 0.2 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.7 PXMP4 PMP24 ENSG00000101417 "Peroxisomal membrane protein 4" Q9Y6I8 20 33702758-33720319 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 73.6;Late spermatids: 44.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CACO-2: 42.3;SK-BR-3: 75.8;T-47d: 64.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050077 Approved Approved "Nucleoli fibrillar center,Peroxisomes" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 11: Alveolar cells - Smell perception" Peroxisomes "Nucleoli fibrillar center" "HPA050077: AB_2681006" "unprognostic (3.41e-2)" "unprognostic (1.11e-1)" "unprognostic (2.59e-1)" "unprognostic (1.75e-1)" "unprognostic (5.08e-2)" "unprognostic (1.30e-2)" "unprognostic (1.17e-1)" "prognostic favorable (3.88e-4)" "unprognostic (3.53e-1)" "unprognostic (4.47e-2)" "unprognostic (4.32e-2)" "unprognostic (1.86e-1)" "prognostic favorable (4.03e-10)" "unprognostic (3.84e-2)" "unprognostic (2.20e-1)" "unprognostic (6.08e-2)" "unprognostic (2.20e-1)" 4.1 11.2 5.1 3.0 5.2 3.2 11.9 3.8 5.6 5.6 4.3 6.2 8.2 4.1 5.1 6.3 6.0 3.3 6.4 5.0 4.0 4.9 8.9 13.9 3.6 4.6 4.5 6.8 6.8 14.7 3.5 3.2 4.1 8.7 5.7 4.4 15.2 6.4 8.0 11.1 7.4 5.1 4.2 4.6 6.8 2.5 5.3 3.5 11.5 6.9 3.9 5.4 5.8 6.5 2.8 12.1 3.3 11.9 5.7 8.3 8.5 8.7 4.7 6.6 2.9 42.3 13.2 0.1 16.2 7.3 16.1 12.5 9.0 10.1 4.7 3.7 3.4 14.0 9.7 0.1 5.3 0.7 10.3 6.4 10.8 9.0 3.0 3.3 4.3 4.4 7.9 8.6 4.7 26.4 12.9 9.8 0.3 21.7 0.0 6.8 16.3 1.7 4.2 9.0 10.7 5.4 24.2 75.8 7.9 1.9 64.0 4.7 8.2 4.7 5.4 11.9 8.2 5.5 13.2 0.2 9.0 4.6 8.1 2.2 11.1 17.5 10.8 22.2 11.3 7.6 10.9 10.9 8.8 9.9 8.3 11.2 2.9 9.1 34.2 5.3 8.5 8.6 5.1 5.2 3.8 5.6 5.0 4.0 4.6 4.5 4.1 4.2 5.3 6.5 5.2 19.2 73.6 7.2 5.5 1.7 4.3 9.4 4.0 11.1 16.8 12.3 12.6 7.2 17.8 18.4 14.6 12.9 3.5 14.2 9.8 8.2 28.7 6.3 6.1 7.6 4.2 9.9 6.4 9.9 24.3 8.5 6.6 5.7 3.8 6.7 8.9 36.0 15.1 5.0 5.7 10.8 6.1 7.5 1.6 44.0 10.5 6.2 3.6 6.5 7.5 13.6 9.2 9.0 10.8 8.5 10.3 11.3 7.0 4.5 23.0 11.2 7.8 11.4 6.6 8.8 7.8 4.6 9.8 9.5 2.4 4.4 5.8 16.9 13.0 4.0 RAB11FIP1 "FLJ22524, FLJ22622, Rab11-FIP1, RCP" ENSG00000156675 "RAB11 family interacting protein 1" Q6WKZ4 8 37858618-37899497 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 798.0;Endometrial ciliated cells: 622.9;Glandular and luminal cells: 969.7;Urothelial cells: 613.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 101.9" "Lineage enriched" "Detected in all" 5 "granulocytes: 101.9" "Cell line enhanced" "Detected in many" "K-562: 73.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB017037, HPA023904, HPA024010, HPA025960" Enhanced Enhanced Vesicles No No "Cluster 50: Neutrophils - Cellular senescence" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 1: K-562 - Erythropoiesis" "Cluster 44: Endometrium - Transcription" Vesicles "CAB017037: , HPA023904: AB_1855990, HPA024010: AB_1855991, HPA025960: AB_1855992" "unprognostic (1.62e-2)" "unprognostic (3.47e-2)" "unprognostic (3.22e-3)" "unprognostic (2.87e-1)" "unprognostic (1.06e-1)" "prognostic favorable (6.61e-4)" "unprognostic (4.32e-1)" "unprognostic (4.50e-3)" "unprognostic (1.58e-1)" "unprognostic (4.72e-2)" "unprognostic (2.82e-3)" "unprognostic (2.73e-2)" "prognostic favorable (1.14e-6)" "unprognostic (4.94e-2)" "unprognostic (8.41e-2)" "unprognostic (9.99e-2)" "unprognostic (1.50e-1)" 7.5 5.7 3.8 17.7 2.7 58.5 21.8 3.8 3.8 14.5 39.3 40.7 41.3 5.9 14.8 47.1 16.9 21.7 12.0 4.4 4.3 13.7 7.2 74.0 17.2 3.4 2.7 4.6 42.5 12.0 8.6 25.8 2.1 8.7 47.0 6.1 23.8 13.5 4.6 18.9 53.5 7.1 2.3 12.0 45.5 6.4 4.0 15.4 13.0 2.7 31.1 23.6 14.9 2.2 41.8 18.1 1.9 8.0 0.4 0.1 54.1 4.2 6.6 7.5 9.6 40.6 23.2 17.0 12.7 5.1 0.4 31.6 14.5 9.4 11.3 44.2 13.5 3.3 9.0 11.9 20.9 7.3 36.3 4.8 12.2 2.8 7.9 11.1 0.1 22.2 73.1 8.2 3.8 9.9 12.4 10.7 12.0 40.9 5.3 3.9 9.7 13.2 39.4 42.2 7.4 8.5 10.6 52.3 13.0 36.8 35.2 14.0 0.6 0.2 23.1 0.6 0.7 16.5 20.7 4.5 0.3 9.8 5.7 24.0 20.5 38.1 4.4 9.4 9.9 6.0 3.2 3.1 18.3 3.8 2.0 2.2 101.9 10.9 20.2 11.0 7.7 10.7 3.8 2.7 3.8 3.8 4.4 4.3 3.4 2.7 2.1 2.3 4.0 2.2 7.6 798.0 112.9 1.0 128.5 15.9 113.5 49.5 24.5 5.4 113.6 58.5 15.8 84.4 228.0 64.4 16.7 44.9 123.6 385.5 15.6 170.2 0.9 622.9 71.4 25.3 243.7 3.8 7.9 248.9 8.1 28.7 272.7 969.7 30.4 2.8 32.2 15.3 32.1 6.7 8.6 312.3 95.6 59.1 174.7 1.8 1.8 121.1 16.0 2.8 95.2 18.6 120.5 0.0 1.0 364.6 299.1 1.5 48.2 192.7 331.9 16.5 348.8 21.0 6.6 9.0 23.3 2.4 5.2 124.2 30.5 96.0 83.8 2.8 256.6 613.9 RAB25 CATX-8 ENSG00000132698 "RAB25, member RAS oncogene family" P57735 1 156061160-156070504 "Cancer-related genes, Predicted intracellular proteins" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 423.3;skin 1: 210.0" "Cell type enhanced" "Detected in many" "Paneth cells: 249.6;Squamous epithelial cells: 300.6;Undifferentiated cells: 244.6;Urothelial cells: 232.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 1.3" "Lineage enriched" "Detected in single" 13 "T-cells: 1.3" "Cell line enhanced" "Detected in some" "BEWO: 120.9;CAPAN-2: 119.9;MCF7: 171.5;OE19: 392.3;RT4: 153.4;SK-BR-3: 243.3;T-47d: 227.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA010872, CAB033645" Enhanced Uncertain "Cell Junctions,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "Cell Junctions, Cytosol" "CAB033645: AB_1128883, HPA010872: AB_1079729" "unprognostic (2.43e-1)" "unprognostic (4.57e-1)" "unprognostic (2.24e-1)" "unprognostic (1.71e-1)" "unprognostic (2.64e-1)" "unprognostic (1.97e-1)" "unprognostic (4.27e-2)" "unprognostic (4.63e-2)" "unprognostic (2.82e-1)" "unprognostic (2.03e-2)" "unprognostic (1.22e-2)" "unprognostic (1.39e-1)" "prognostic favorable (1.38e-6)" "unprognostic (2.31e-2)" "unprognostic (3.24e-2)" "unprognostic (3.14e-2)" "unprognostic (4.94e-2)" 0.6 0.1 0.1 10.2 0.1 0.1 52.0 0.3 0.3 76.2 0.0 86.2 72.9 7.3 37.5 423.3 47.5 26.4 0.1 0.0 0.0 41.6 1.7 39.2 0.4 0.1 0.1 0.4 57.1 68.9 27.5 12.4 0.1 36.3 78.1 0.0 105.3 28.4 0.9 210.0 65.6 3.7 0.2 0.2 80.9 0.3 0.1 10.1 50.6 0.0 44.0 69.9 148.2 0.3 93.3 0.0 0.0 0.0 0.0 0.0 120.9 0.0 0.0 0.0 0.0 90.4 119.9 0.0 0.1 0.0 0.0 109.5 0.0 51.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 105.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 171.5 0.0 0.4 4.8 392.3 0.0 0.1 0.0 0.3 0.0 153.4 13.3 0.0 0.0 243.3 0.3 21.1 227.9 0.4 0.0 0.2 0.2 0.0 0.2 0.0 1.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 1.0 0.2 0.0 0.0 1.2 1.1 0.0 0.0 0.0 0.0 0.3 0.2 0.1 0.1 0.3 0.3 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.3 1.2 28.9 41.0 0.0 1.5 55.1 102.9 113.9 74.0 0.0 121.4 137.7 0.1 94.4 98.7 86.5 0.0 102.1 2.3 197.8 166.3 170.4 0.0 58.6 6.4 2.6 85.4 0.0 0.1 150.3 30.0 2.3 96.4 66.2 5.7 0.0 0.0 0.4 7.3 0.0 0.1 208.5 89.5 0.0 5.8 0.0 0.3 2.1 21.4 0.0 3.6 0.0 0.0 0.0 0.1 197.3 249.6 0.0 0.3 114.0 195.9 35.5 66.3 0.0 0.0 0.0 6.8 0.2 1.1 300.6 154.7 80.3 2.7 0.0 244.6 232.3 RAD54L "hHR54, hRAD54, RAD54A" ENSG00000085999 "RAD54 like" Q92698 1 46246461-46278480 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 15.4;testis: 15.6" "Cell type enhanced" "Detected in many" "Erythroid cells: 7.2;Extravillous trophoblasts: 9.4;Glandular and luminal cells: 8.0;Spermatocytes: 12.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.1" "Lineage enhanced" "Detected in single" "T-cells: 1.1" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA028954, HPA051537" Approved Enhanced Nucleoplasm NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA028954: AB_2672840, HPA051537: AB_2681525" "unprognostic (2.12e-2)" "prognostic favorable (6.67e-4)" "unprognostic (5.12e-2)" "unprognostic (5.36e-3)" "unprognostic (3.24e-1)" "unprognostic (1.08e-2)" "unprognostic (9.75e-6)" "unprognostic (3.91e-2)" "unprognostic (2.17e-3)" "unprognostic (2.95e-2)" "unprognostic (1.77e-4)" "unprognostic (5.58e-2)" "unprognostic (1.11e-16)" "unprognostic (6.76e-3)" "unprognostic (1.66e-1)" "unprognostic (2.67e-1)" "unprognostic (1.74e-1)" 0.5 0.7 3.0 4.1 3.8 8.7 1.0 4.3 3.9 1.3 2.1 3.2 2.0 0.7 0.1 5.4 0.4 0.5 0.7 2.9 2.5 1.4 0.5 1.2 5.5 3.2 3.0 0.5 0.5 0.3 0.4 3.4 3.8 1.0 4.6 0.4 0.9 0.4 1.2 2.3 2.8 1.7 2.8 2.8 1.5 15.6 3.1 15.4 1.8 0.0 8.3 0.8 1.8 3.7 22.2 16.1 46.8 29.1 3.3 2.4 43.9 25.8 11.3 42.8 43.3 33.3 14.2 42.5 19.1 11.0 38.5 22.2 44.6 14.5 36.8 23.7 43.0 53.0 49.7 32.1 0.1 54.0 29.3 1.6 1.2 42.1 12.5 6.9 13.5 49.7 38.2 41.7 23.1 20.4 68.9 60.0 42.5 19.4 25.2 52.8 26.8 19.0 9.4 17.5 22.4 16.3 18.4 25.2 5.7 38.0 9.1 37.7 5.7 43.9 26.1 23.6 43.7 17.6 10.6 46.9 11.5 35.1 18.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.1 0.2 3.0 3.8 4.3 3.9 2.9 2.5 3.2 3.0 3.8 2.8 3.1 3.7 0.0 0.0 0.0 1.0 0.7 0.3 0.7 0.5 1.8 0.0 0.5 0.5 0.8 0.0 0.1 0.0 0.0 4.3 0.4 1.8 0.0 0.3 2.7 2.3 0.8 0.5 0.0 7.2 2.8 0.0 9.4 1.1 0.5 8.0 4.5 5.6 0.4 0.0 2.6 0.0 1.1 1.3 0.0 0.3 0.3 0.7 0.0 0.4 0.0 0.0 0.0 0.0 1.0 1.0 2.9 0.3 0.1 0.0 4.7 0.4 0.4 0.0 0.1 0.0 0.0 0.4 4.0 12.4 5.6 3.1 0.3 1.6 1.1 0.2 2.9 1.0 RDH12 "FLJ30273, LCA13, RP53, SDR7C2" ENSG00000139988 "Retinol dehydrogenase 12" Q96NR8 14 67701886-67734451 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Sensory transduction, Vision" Oxidoreductase "Disease variant, Leber congenital amaurosis, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "retina: 222.7;skin 1: 63.8" "Group enriched" "Detected in some" 5 "Cone photoreceptor cells: 146.0;Rod photoreceptor cells: 453.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 5.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA "Cluster 79: Retina - Phototransduction" "Cluster 46: Photoreceptor cells - Phototransduction" "unprognostic (4.25e-3)" "unprognostic (4.50e-3)" "unprognostic (1.16e-1)" "unprognostic (7.53e-2)" "unprognostic (2.99e-1)" "unprognostic (1.99e-1)" "unprognostic (6.70e-2)" "unprognostic (2.13e-1)" "unprognostic (1.69e-2)" "unprognostic (2.72e-3)" "unprognostic (7.59e-2)" "unprognostic (2.02e-1)" "unprognostic (1.42e-2)" "unprognostic (6.47e-2)" "unprognostic (7.83e-2)" "unprognostic (3.58e-1)" "unprognostic (3.92e-1)" 0.1 4.1 1.3 0.1 1.0 0.1 2.2 1.0 1.4 11.0 0.4 0.0 0.3 0.0 8.7 22.1 0.5 17.6 0.0 0.9 1.2 13.6 3.8 0.1 0.0 1.2 2.3 0.0 3.2 0.0 0.9 0.1 1.2 0.5 0.0 222.7 1.7 0.1 0.1 63.8 0.1 0.0 0.6 0.0 12.4 0.1 4.6 0.4 1.2 0.0 1.6 0.0 23.6 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.5 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.4 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.0 1.0 1.4 0.9 1.2 1.2 2.3 1.2 0.6 4.6 1.1 0.0 0.0 0.0 0.7 0.0 4.7 0.3 0.0 0.6 39.8 0.1 0.1 0.0 20.0 0.3 1.8 146.0 0.0 0.0 0.1 0.0 0.7 0.2 1.8 1.1 2.2 0.0 0.0 1.2 1.7 0.0 0.4 14.3 1.7 0.0 0.0 0.0 5.7 0.2 20.2 0.9 0.0 0.0 0.6 0.9 0.0 0.3 0.2 1.8 1.0 0.0 53.0 0.0 1.5 0.2 1.5 2.6 0.0 0.0 0.3 0.1 12.5 0.2 453.2 0.0 0.0 0.2 0.0 0.1 4.7 38.6 0.0 0.1 0.1 0.1 0.3 RHBDL2 FLJ20435 ENSG00000158315 "Rhomboid like 2" Q9NX52 1 38885807-38941830 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 24.4" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 74.6;Club cells: 44.8;Distal enterocytes: 52.2;Ionocytes: 46.8;Oligodendrocytes: 53.9;Pancreatic endocrine cells: 53.0;Urothelial cells: 49.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "A-431: 12.7;CAPAN-2: 41.7;HaCaT: 21.7;RT4: 40.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA043807 Approved NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA043807: AB_10961118" "unprognostic (3.34e-2)" "unprognostic (2.96e-1)" "unprognostic (4.57e-2)" "unprognostic (2.56e-1)" "unprognostic (7.26e-3)" "unprognostic (2.19e-2)" "unprognostic (1.04e-3)" "unprognostic (5.81e-2)" "unprognostic (2.36e-1)" "unprognostic (2.87e-1)" "unprognostic (4.07e-3)" "unprognostic (1.23e-1)" "unprognostic (7.47e-9)" "unprognostic (1.11e-2)" "unprognostic (2.46e-1)" "unprognostic (4.12e-2)" "unprognostic (4.20e-2)" 2.2 0.4 4.1 1.7 8.8 0.4 2.0 5.6 7.1 4.3 0.3 18.0 1.3 0.6 0.2 24.4 1.1 3.4 7.7 4.0 4.9 0.9 0.4 1.0 0.8 10.0 9.5 0.3 0.6 0.3 1.3 1.1 7.3 1.8 18.0 1.1 7.8 0.5 0.5 16.6 0.8 1.1 4.1 0.4 15.7 7.3 7.4 0.7 0.7 0.0 7.1 9.7 12.8 11.4 12.7 4.3 0.4 0.2 0.2 1.2 1.2 0.7 0.1 0.9 0.1 0.9 41.7 0.3 3.0 6.3 4.2 21.7 0.0 7.1 0.6 0.3 0.2 0.2 2.9 2.5 0.5 0.1 0.5 0.9 1.0 6.0 0.1 4.0 1.0 0.4 0.0 0.4 0.9 0.0 0.1 0.3 0.2 1.3 1.2 0.2 0.2 0.0 0.0 40.4 0.4 0.3 5.0 11.4 0.4 0.6 5.6 0.4 0.9 4.4 0.5 0.3 0.3 0.4 0.5 0.5 4.1 0.8 0.2 1.5 0.6 0.4 0.2 0.4 0.1 0.7 0.2 0.1 0.7 0.3 0.2 0.2 1.7 0.3 0.2 0.7 0.3 0.3 4.1 8.8 5.6 7.1 4.0 4.9 10.0 9.5 7.3 4.1 7.4 11.4 1.3 0.0 0.5 11.1 0.7 17.7 8.0 74.6 5.2 2.7 3.9 2.4 0.4 5.7 44.8 3.7 0.0 0.4 0.2 52.2 0.0 12.4 3.9 4.7 3.4 1.4 2.4 0.0 19.0 15.8 0.3 2.1 27.5 8.4 4.5 1.6 1.8 0.0 0.2 1.7 21.9 17.3 46.8 0.0 2.7 1.0 0.6 0.4 1.8 4.7 0.6 1.3 0.0 10.6 53.9 53.0 22.3 0.0 0.2 13.4 0.2 0.3 33.2 1.8 6.6 1.2 4.0 0.3 0.1 19.0 28.4 0.7 0.5 0.2 30.2 49.9 RHOV "ARHV, Chp, WRCH2" ENSG00000104140 "Ras homolog family member V" Q96L33 15 40872214-40874234 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 211.8;skin 1: 129.8;vagina: 92.2" "Cell type enhanced" "Detected in many" "Paneth cells: 142.3;Squamous epithelial cells: 375.0;Suprabasal keratinocytes: 283.0;Urothelial cells: 275.1" "Cancer enhanced" "Detected in many" "cervical cancer: 91.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 4 "SK-BR-3: 328.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053343 Enhanced NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA053343: AB_2682122" "unprognostic (1.42e-1)" "unprognostic (2.06e-1)" "unprognostic (8.29e-3)" "unprognostic (4.34e-2)" "unprognostic (2.20e-2)" "unprognostic (1.52e-2)" "unprognostic (2.33e-2)" "prognostic unfavorable (2.33e-4)" "unprognostic (1.71e-1)" "unprognostic (1.48e-1)" "prognostic unfavorable (4.19e-4)" "unprognostic (3.29e-3)" "unprognostic (1.05e-1)" "unprognostic (2.16e-2)" "unprognostic (1.23e-2)" "unprognostic (8.43e-3)" "unprognostic (5.63e-3)" 0.5 0.1 0.9 0.2 0.9 0.2 16.0 1.1 1.8 26.3 0.5 2.8 0.6 0.7 9.5 211.8 2.7 0.5 0.1 1.0 1.1 5.5 0.2 2.3 0.2 2.1 0.8 0.3 16.3 2.2 3.0 3.2 2.4 16.6 2.6 0.0 44.3 2.4 0.2 129.8 0.6 0.1 0.8 0.1 1.2 0.3 1.9 2.6 0.5 0.0 23.3 20.7 92.2 0.9 1.6 9.7 0.1 2.7 0.2 0.0 5.2 0.1 0.8 0.4 0.2 4.0 4.4 0.0 2.4 0.0 0.3 77.9 4.5 0.6 0.2 10.5 12.5 0.5 11.3 0.6 0.0 0.5 0.0 0.3 6.0 0.3 0.1 0.4 0.1 2.3 2.1 0.5 0.0 27.2 0.6 2.3 1.7 19.3 3.7 4.0 0.4 1.8 5.1 34.3 4.0 0.8 8.0 328.9 0.2 0.5 40.9 0.3 0.1 0.0 1.1 0.2 0.3 0.0 0.4 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.9 1.1 1.8 1.0 1.1 2.1 0.8 2.4 0.8 1.9 0.9 0.6 0.0 3.2 0.3 0.5 84.1 42.5 80.9 19.9 0.0 75.2 48.5 0.9 2.8 103.0 29.5 0.0 60.7 1.9 43.1 13.7 107.5 0.0 18.5 1.9 2.5 22.7 0.0 1.5 56.2 6.0 2.0 7.1 25.5 1.3 0.4 0.0 0.0 4.6 0.0 0.5 54.7 67.1 0.0 13.3 0.0 0.0 0.8 32.0 0.0 3.6 0.0 0.0 0.0 0.3 13.8 142.3 0.7 0.1 89.8 1.0 0.9 26.2 0.0 0.0 0.2 7.3 0.0 0.9 375.0 283.0 42.4 1.9 0.0 66.3 275.1 RHPN2 ENSG00000131941 "Rhophilin Rho GTPase binding protein 2" Q8IUC4 19 32978592-33064888 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 61.0;Endometrial ciliated cells: 90.2;Gastric mucus-secreting cells: 94.8;Glandular and luminal cells: 108.8;Muller glia cells: 76.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 52.4;OE19: 50.7;RPTEC TERT1: 52.9;SK-BR-3: 54.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051749 Uncertain NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" "HPA051749: AB_2681589" "unprognostic (1.18e-1)" "unprognostic (1.33e-1)" "unprognostic (1.17e-2)" "unprognostic (3.65e-2)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.58e-4)" "unprognostic (3.52e-2)" "unprognostic (2.08e-3)" "unprognostic (2.32e-1)" "unprognostic (5.07e-3)" "unprognostic (3.01e-3)" "unprognostic (1.26e-1)" "prognostic favorable (1.22e-8)" "unprognostic (3.74e-2)" "unprognostic (4.44e-2)" "unprognostic (5.81e-2)" "unprognostic (4.40e-2)" 3.0 0.8 5.5 4.4 5.9 0.0 12.7 5.8 6.6 8.4 7.8 23.6 21.7 5.4 2.4 1.2 15.0 13.6 1.5 5.2 5.8 14.5 19.6 4.1 1.3 6.3 6.9 1.7 12.4 16.9 4.8 8.2 6.1 27.1 19.0 20.2 19.4 2.2 0.3 10.5 17.8 1.8 5.1 0.9 35.2 0.7 7.2 1.9 5.4 0.9 2.6 11.5 1.1 6.4 28.6 52.4 4.9 8.6 1.0 0.1 24.5 6.6 5.0 10.0 10.5 45.9 28.6 0.0 41.1 3.7 8.8 13.5 15.9 5.8 12.4 13.2 9.7 3.2 5.9 17.9 6.6 0.0 4.1 1.2 11.5 8.4 4.7 7.6 1.3 1.2 7.2 0.0 3.0 24.4 0.1 2.9 10.5 50.7 8.4 0.0 6.0 5.6 52.9 14.0 11.0 5.8 11.2 54.5 13.4 13.9 15.2 1.4 0.7 0.1 12.7 3.6 11.2 6.3 4.6 2.1 1.6 0.0 16.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 5.9 5.8 6.6 5.2 5.8 6.3 6.9 6.1 5.1 7.2 6.4 0.3 22.4 1.1 20.2 3.9 1.3 6.3 6.2 7.4 1.9 30.4 15.4 0.9 17.2 14.7 12.9 12.5 18.2 2.1 61.0 3.9 31.0 0.4 90.2 11.1 1.1 4.8 0.0 1.3 13.1 6.8 6.4 94.8 108.8 1.3 0.2 3.3 13.0 1.9 0.0 1.4 22.2 18.3 3.0 0.0 0.3 2.1 1.6 1.8 4.7 0.0 76.8 0.0 9.5 1.6 33.8 52.6 1.2 6.1 23.5 11.7 19.8 51.9 10.1 0.0 0.6 3.7 0.0 1.4 3.8 1.8 3.4 1.1 0.0 23.3 36.1 RIN1 ENSG00000174791 "Ras and Rab interactor 1" Q13671 11 66330241-66336840 "Predicted intracellular proteins, RAS pathway related proteins" Endocytosis "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 26.6" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 25.7;Basal squamous epithelial cells: 23.3;Squamous epithelial cells: 18.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 9.7" "Lineage enriched" "Detected in many" 6 "monocytes: 9.7" "Cell line enhanced" "Detected in many" "hTCEpi: 44.3;U-2197: 40.7" "Low region specificity" "Detected in many" HPA035491 Uncertain Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nuclear membrane" Nucleoplasm "HPA035491: AB_10601608" "unprognostic (1.25e-2)" "unprognostic (1.04e-1)" "unprognostic (4.69e-2)" "prognostic favorable (2.21e-4)" "unprognostic (1.11e-2)" "unprognostic (2.57e-1)" "unprognostic (6.82e-3)" "unprognostic (3.84e-2)" "unprognostic (1.11e-2)" "unprognostic (2.52e-3)" "unprognostic (8.32e-2)" "unprognostic (2.99e-1)" "prognostic unfavorable (9.34e-7)" "unprognostic (2.42e-2)" "unprognostic (1.14e-1)" "unprognostic (7.82e-3)" "unprognostic (2.46e-1)" 4.8 4.3 3.7 2.3 4.9 1.1 4.4 3.3 5.7 8.3 1.5 5.2 2.7 4.4 0.2 20.4 5.6 1.4 3.4 6.3 1.6 4.3 1.3 4.9 0.5 1.0 1.2 3.7 5.2 0.4 7.2 1.4 1.1 7.1 1.0 0.2 5.1 0.8 7.5 26.6 4.3 0.6 0.8 6.1 6.8 3.7 2.0 0.5 2.4 0.5 0.4 5.4 11.3 2.6 2.3 5.7 2.3 5.3 2.8 14.5 1.2 13.7 18.0 14.4 6.8 3.3 9.3 0.5 5.0 13.6 5.2 12.9 0.0 24.3 1.8 1.1 0.0 0.8 4.4 4.1 5.5 0.1 4.2 15.9 44.3 12.4 8.0 17.1 2.8 0.6 0.3 0.1 6.1 0.5 0.3 11.0 0.6 3.9 12.6 0.1 5.4 0.1 3.9 3.0 10.9 2.3 3.2 2.5 20.5 0.6 1.8 1.3 6.5 18.7 7.9 40.7 3.3 0.3 0.9 0.0 26.9 3.5 6.3 0.1 2.7 0.0 0.2 4.7 0.6 0.1 0.4 0.2 1.7 0.0 0.5 0.2 0.0 0.1 9.7 0.0 0.1 1.8 3.7 4.9 3.3 5.7 6.3 1.6 1.0 1.2 1.1 0.8 2.0 2.6 3.9 0.0 0.5 1.3 0.8 13.4 9.3 25.7 23.3 3.8 3.5 4.3 0.8 4.3 4.8 0.0 0.0 0.8 0.5 9.6 0.0 4.1 0.5 2.4 5.1 5.3 3.0 0.0 6.0 6.9 4.8 5.6 5.6 1.8 4.5 0.1 7.9 0.2 4.7 0.0 2.3 4.5 2.0 8.7 6.5 2.0 4.4 6.4 1.8 1.0 8.1 0.7 1.0 0.5 0.5 8.9 7.8 1.9 1.4 4.0 9.1 0.1 3.4 1.2 0.0 4.2 3.4 1.2 0.9 18.6 15.2 0.3 2.2 1.6 9.2 5.8 RNASE7 RAE1 ENSG00000165799 "Ribonuclease A family member 7" Q9H1E1 14 21042316-21044234 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 74.9;lymphoid tissue: 24.1;skin 1: 27.9" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 30.2;Cholangiocytes: 8.6;Prostatic glandular cells: 7.3;Urothelial cells: 27.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 17.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HBEC3-KT: 24.7;hTCEpi: 10.3;hTERT-HME1: 53.3" "HPA005690, CAB062560, CAB068225" Enhanced "Secreted in other tissues" NA NA 280000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "CAB062560: AB_2665595, CAB068225: AB_2665594, HPA005690: AB_1079819" "unprognostic (1.13e-2)" "unprognostic (3.21e-1)" "unprognostic (5.84e-2)" "unprognostic (2.53e-1)" "unprognostic (1.71e-1)" "unprognostic (8.27e-2)" "unprognostic (7.80e-2)" "unprognostic (8.73e-2)" "unprognostic (3.28e-1)" "unprognostic (1.15e-1)" "unprognostic (2.25e-2)" "unprognostic (1.94e-1)" "unprognostic (2.17e-2)" "unprognostic (1.74e-1)" "unprognostic (8.23e-2)" "unprognostic (3.24e-1)" "unprognostic (3.42e-1)" 0.1 0.1 0.0 0.0 0.0 0.0 3.0 0.0 0.0 2.5 0.0 0.2 0.0 0.0 0.0 74.9 0.0 6.6 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.3 0.5 0.0 4.7 0.5 0.3 27.9 0.0 0.0 0.0 0.1 0.0 0.2 0.0 2.0 0.0 0.0 24.1 0.2 9.3 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 24.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.3 0.1 53.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 30.2 1.5 0.0 0.0 0.1 2.4 0.5 8.6 0.4 0.0 0.0 1.5 0.0 0.1 0.0 4.5 0.9 1.3 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 2.0 0.0 0.3 5.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 7.3 0.0 0.0 2.7 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.6 5.3 0.3 0.0 0.2 27.2 RNF141 "ZFP26, ZNF230" ENSG00000110315 "Ring finger protein 141" Q8WVD5 11 10511673-10541230 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 7 "Early spermatids: 1045.8;Late spermatids: 666.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "CAPAN-2: 176.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018133 Approved Approved Nucleoplasm,Microtubules NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 78: Testis - Spermatogenesis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 34: Spermatids - Unknown function" Microtubules Nucleoplasm "HPA018133: AB_1859142" "unprognostic (7.41e-2)" "unprognostic (1.16e-1)" "unprognostic (7.88e-3)" "unprognostic (8.42e-2)" "unprognostic (2.12e-1)" "unprognostic (3.09e-2)" "unprognostic (1.08e-3)" "unprognostic (1.48e-1)" "unprognostic (1.44e-1)" "unprognostic (5.50e-2)" "prognostic unfavorable (1.14e-4)" "unprognostic (4.57e-2)" "prognostic favorable (2.60e-4)" "unprognostic (6.11e-2)" "unprognostic (1.30e-1)" "unprognostic (1.71e-2)" "unprognostic (1.61e-2)" 24.0 28.3 41.2 26.8 61.9 19.8 26.9 56.4 61.6 17.6 22.9 17.3 21.7 13.7 19.7 56.3 16.3 14.5 22.7 34.0 51.6 23.5 21.8 21.7 17.9 61.3 52.7 10.9 14.5 30.6 10.0 14.9 63.4 22.6 16.8 18.6 38.3 14.2 43.4 42.9 30.0 13.3 52.1 27.7 21.6 82.7 48.4 18.8 22.9 35.7 25.6 21.0 22.9 79.7 48.3 24.6 34.5 21.1 51.7 50.2 24.6 32.2 26.1 12.6 15.1 38.3 176.3 19.9 28.3 25.0 22.3 34.8 15.3 38.4 19.0 21.7 20.1 13.3 15.8 19.9 20.0 22.2 15.2 33.0 44.0 6.7 41.1 45.8 33.9 25.2 38.4 18.7 31.6 20.6 21.2 8.3 17.5 32.3 14.0 27.3 14.8 22.9 20.4 52.9 11.0 21.5 31.1 36.8 20.6 29.5 23.4 11.3 36.3 30.1 18.5 24.6 10.4 8.2 16.5 22.7 37.7 31.3 37.3 34.2 52.3 92.7 8.3 106.8 13.9 67.6 9.6 8.1 28.9 69.9 10.5 7.3 152.4 9.2 103.9 26.6 12.8 33.9 41.2 61.9 56.4 61.6 34.0 51.6 61.3 52.7 63.4 52.1 48.4 79.7 15.1 19.2 49.2 14.4 39.4 40.8 39.7 47.7 37.0 20.3 31.7 22.0 46.7 18.6 36.9 20.2 12.5 14.4 18.8 16.6 41.1 21.2 1045.8 18.5 14.0 18.4 21.0 15.4 10.7 24.7 15.1 15.9 16.8 23.0 13.3 18.8 21.0 28.0 41.6 37.0 11.8 28.2 16.2 107.4 10.5 666.5 19.6 52.6 19.6 4.7 41.7 27.8 4.1 12.1 67.9 41.6 11.2 19.5 15.2 53.3 58.8 33.5 48.0 11.0 6.6 19.1 18.6 83.4 39.4 49.1 40.1 17.9 11.7 23.3 21.1 74.8 RNF225 ENSG00000269855 "Ring finger protein 225" M0QZC1 19 58396090-58397079 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 2.9;esophagus: 6.6;skin 1: 4.6;vagina: 2.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "head and neck cancer: 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "unprognostic (3.07e-1)" "unprognostic (6.94e-2)" "unprognostic (3.68e-3)" "unprognostic (2.19e-1)" "unprognostic (4.95e-2)" "unprognostic (1.67e-2)" "unprognostic (1.00e-2)" "unprognostic (1.75e-3)" "unprognostic (1.40e-1)" "unprognostic (3.42e-1)" "unprognostic (9.18e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.1 2.9 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 1.2 0.2 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.3 0.1 2.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 ROPN1B ENSG00000114547 "Rhophilin associated tail protein 1B" Q9BZX4 3 125969160-125983454 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 214.2" "Group enriched" "Detected in many" 4 "Early spermatids: 2012.7;Late spermatids: 1967.9" "Group enriched" "Detected in some" 5 "breast cancer: 1.3;melanoma: 4.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "SK-MEL-30: 54.6;WM-115: 18.5" HPA052530 Supported NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 34: Spermatids - Unknown function" "HPA052530: AB_2681861" "unprognostic (7.73e-3)" "unprognostic (1.35e-2)" "unprognostic (2.22e-3)" "unprognostic (2.76e-2)" "unprognostic (7.19e-2)" "unprognostic (3.39e-2)" "unprognostic (1.21e-2)" "unprognostic (2.12e-1)" "unprognostic (8.15e-2)" "unprognostic (1.96e-2)" "unprognostic (1.09e-2)" "unprognostic (8.18e-2)" "unprognostic (5.91e-2)" "unprognostic (5.01e-2)" "unprognostic (1.74e-2)" "unprognostic (6.89e-3)" "unprognostic (3.78e-2)" 0.3 0.5 1.3 0.2 1.6 0.1 38.2 2.0 1.8 0.2 0.0 0.1 0.1 0.3 22.1 0.1 0.5 0.0 3.0 1.3 1.2 0.3 1.2 0.3 0.6 0.8 1.3 0.3 0.3 0.0 3.0 0.2 0.9 0.7 0.0 1.8 14.6 0.2 0.4 7.0 0.1 0.0 0.5 0.1 0.1 214.2 0.9 0.0 0.7 0.8 0.3 0.4 0.1 2.0 0.0 0.0 0.3 0.2 0.0 0.0 2.9 0.0 0.3 0.2 0.2 0.2 2.4 1.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 1.4 0.0 0.1 1.1 0.2 0.0 0.8 0.0 0.0 0.0 0.5 0.0 0.3 0.9 0.3 0.1 0.0 54.6 0.1 0.7 0.7 0.0 0.0 0.5 0.2 0.2 5.4 1.1 0.3 0.0 0.0 18.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.3 1.6 2.0 1.8 1.3 1.2 0.8 1.3 0.9 0.5 0.9 2.0 0.6 0.0 0.0 1.3 0.3 3.7 0.1 1.4 0.0 0.2 60.1 86.2 18.8 0.0 3.9 0.0 0.0 0.3 2.0 0.0 0.0 0.2 2012.7 3.1 0.1 1.6 0.0 0.0 0.5 0.2 2.5 1.3 0.0 0.1 0.0 0.2 0.0 0.5 0.1 3.3 0.4 0.0 2.0 0.0 2.0 1967.9 19.0 1.5 149.4 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 9.8 0.0 0.6 0.0 0.1 17.8 0.2 19.7 0.0 1.0 493.4 11.8 0.0 0.6 0.1 0.5 0.0 0.0 1.2 ROS1 "c-ros-1, MCF3, ROS" ENSG00000047936 "ROS proto-oncogene 1, receptor tyrosine kinase" P08922 6 117287353-117425942 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 18 "epididymis: 58.6;lung: 31.7" "Cell type enriched" "Detected in some" 4 "Alveolar cells type 2: 78.5" "Cancer enriched" "Detected in some" 13 "lung cancer: 6.9" "Region enriched" "Detected in single" 4 "cerebral cortex: 2.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "GAMG: 19.3;HSkMC: 10.1;hTCEpi: 21.7;LHCN-M2: 14.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA049098, HPA072424" Uncertain Approved Vesicles NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 30: Epithelial cell lines - Translation" "Cluster 11: Alveolar cells - Smell perception" Vesicles "HPA049098: AB_2680628, HPA072424: AB_2686519" "unprognostic (8.18e-2)" "unprognostic (4.64e-3)" "unprognostic (1.60e-1)" "unprognostic (2.37e-2)" "unprognostic (7.57e-2)" "unprognostic (2.05e-2)" "unprognostic (1.57e-1)" "unprognostic (1.79e-1)" "unprognostic (2.79e-2)" "unprognostic (1.00e-2)" "unprognostic (2.42e-1)" "unprognostic (5.20e-2)" "unprognostic (1.56e-12)" "unprognostic (1.09e-2)" "unprognostic (2.81e-1)" "unprognostic (1.91e-1)" "unprognostic (2.12e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.2 0.0 0.4 0.0 0.0 58.6 0.0 0.1 0.0 0.0 0.6 0.0 0.3 0.1 31.7 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.0 0.0 0.4 0.0 0.0 2.2 0.4 0.3 0.2 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.3 0.3 0.0 0.0 0.1 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 10.1 21.7 0.2 1.9 0.0 0.0 0.0 0.0 0.0 14.9 0.0 0.0 0.2 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 2.0 0.0 3.1 1.7 0.2 2.1 0.0 0.0 0.0 1.9 3.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 16.0 78.5 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.0 0.8 0.0 3.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.3 1.8 0.2 0.0 0.0 0.0 17.8 0.0 0.0 0.2 0.0 1.5 1.3 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 1.3 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 RPLP1 LP1 ENSG00000137818 "Ribosomal protein lateral stalk subunit P1" P05386 15 69452814-69456205 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Suprabasal keratinocytes: 28402.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003368 Supported "Endoplasmic reticulum,Cytosol" NA NA 2000000 "Cluster 30: Non-specific - Translation" "Cluster 59: Non-specific - Translation" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 32: Non-specific - Translation" "Endoplasmic reticulum, Cytosol" "HPA003368: AB_1079845" "unprognostic (5.04e-3)" "unprognostic (2.26e-2)" "unprognostic (2.02e-2)" "unprognostic (4.29e-2)" "unprognostic (6.32e-2)" "unprognostic (1.35e-1)" "unprognostic (4.36e-2)" "unprognostic (2.92e-1)" "unprognostic (1.30e-1)" "unprognostic (2.36e-1)" "unprognostic (2.79e-1)" "unprognostic (9.55e-2)" "prognostic unfavorable (2.30e-9)" "unprognostic (7.75e-2)" "unprognostic (1.57e-1)" "unprognostic (2.59e-1)" "unprognostic (5.83e-2)" 1779.5 1664.6 852.0 893.4 872.7 2781.2 1895.2 821.7 1109.7 2465.3 920.5 2035.4 1200.3 1805.3 349.4 2773.4 1670.9 579.0 2121.7 813.6 844.4 1703.1 1566.2 1439.7 1583.3 871.6 857.5 3354.5 2003.6 264.6 924.6 565.5 866.0 1991.6 449.1 157.6 1705.8 417.0 4746.4 4498.6 1693.4 529.7 892.5 1992.0 2147.0 492.5 873.6 643.5 1140.9 761.4 1017.9 2099.9 2372.6 891.4 1890.5 1882.4 827.9 1919.4 1172.4 1394.2 1770.4 1615.7 960.9 892.0 711.8 1918.7 1861.9 2622.2 2346.4 869.5 811.2 2521.6 1296.6 1287.5 193.1 2639.9 3956.6 2208.5 2153.1 1914.5 2045.2 1976.4 1931.2 1782.1 2199.9 653.6 1219.6 1438.9 1092.7 2265.9 2127.7 2160.7 642.2 1757.0 2163.4 5781.3 3098.7 1172.2 1802.9 2192.5 2696.6 3893.7 876.0 2002.9 1319.3 2558.5 1620.5 1978.2 6979.8 742.8 1633.9 4449.5 1915.7 1273.2 2851.6 1535.0 2672.3 4382.2 7690.0 2245.6 1524.1 4968.6 1076.9 2903.3 5350.5 1819.3 3182.4 3677.4 5811.2 9096.0 6532.4 4349.4 6100.6 7551.7 6871.8 6057.1 733.9 5147.0 2138.6 6392.6 5921.8 13416.9 852.0 872.7 821.7 1109.7 813.6 844.4 871.6 857.5 866.0 892.5 873.6 891.4 3508.0 1891.0 3795.4 16.0 11229.3 24186.3 18565.6 9896.5 18630.1 626.6 14197.1 19613.8 1854.3 3877.6 5293.4 2265.9 350.3 9217.3 6668.2 2484.5 5141.7 5608.7 475.1 2702.4 5765.4 5131.7 2926.5 6423.8 19.7 7158.4 12076.7 5235.1 3541.4 4232.4 2605.7 4287.7 5261.2 6536.1 8166.9 373.5 22.5 7238.9 2396.6 8309.7 12226.0 1764.3 8447.2 6779.7 9051.8 28.1 11829.2 4015.4 6451.2 15.6 42.8 7495.3 5127.5 4732.9 10308.0 16198.4 5565.3 8039.9 2204.8 1167.3 2530.9 5356.8 5872.6 690.3 1864.1 18779.3 28402.5 9502.3 9179.6 6940.6 8549.1 17342.5 RTN4RL1 "DKFZp547J144, NgR3, NGRH2" ENSG00000185924 "Reticulon 4 receptor like 1" Q86UN2 17 1934677-2025334 "Predicted intracellular proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 12.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 20.6;Cone photoreceptor cells: 37.5;Excitatory neurons: 43.5;Horizontal cells: 33.7;Inhibitory neurons: 18.6" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "hippocampal formation: 12.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 10.9;HaCaT: 10.8;hTCEpi: 10.1;T-47d: 13.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044428 Uncertain Approved "Nucleoplasm,Plasma membrane,Actin filaments,Midbody" "Intracellular and membrane" Yes NA 35000 "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Actin filaments" "Nucleoplasm, Plasma membrane, Midbody" "HPA044428: AB_10963229" "unprognostic (5.23e-1)" "unprognostic (3.52e-2)" "unprognostic (2.06e-1)" "unprognostic (2.12e-1)" "unprognostic (2.93e-2)" "unprognostic (7.25e-2)" "unprognostic (2.61e-3)" "unprognostic (1.17e-1)" "unprognostic (8.97e-3)" "unprognostic (6.21e-2)" "unprognostic (2.55e-3)" "unprognostic (6.32e-3)" "prognostic unfavorable (7.69e-4)" "unprognostic (3.86e-2)" "unprognostic (1.05e-1)" "unprognostic (7.01e-2)" "unprognostic (3.15e-2)" 4.0 3.1 4.6 0.3 4.0 0.0 6.4 0.0 9.2 2.1 0.0 0.4 0.1 0.8 0.2 1.3 1.5 0.6 2.3 12.3 0.3 1.6 2.6 1.6 0.1 0.0 0.5 0.9 1.8 1.3 5.9 0.3 0.0 3.4 0.1 8.5 4.4 2.0 1.8 9.6 0.5 0.3 0.0 1.1 0.7 0.8 1.9 0.2 1.4 0.4 0.1 1.5 2.2 0.0 1.4 1.6 1.8 2.5 2.0 0.3 0.0 0.1 1.1 0.3 0.0 0.0 0.0 0.0 0.1 10.9 0.2 10.8 4.6 0.1 0.1 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 10.1 0.0 3.6 0.0 0.0 2.5 0.1 0.0 0.1 0.5 0.0 0.0 0.3 0.0 0.3 0.8 0.3 1.2 0.0 0.0 2.2 0.0 0.3 0.8 1.7 0.2 13.3 0.1 0.0 0.0 0.2 0.5 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 4.0 0.0 9.2 12.3 0.3 0.0 0.5 0.0 0.0 1.9 0.0 1.0 0.0 2.2 1.6 0.1 2.7 0.2 0.0 1.8 20.6 5.4 4.3 3.0 1.5 1.3 3.7 37.5 0.0 0.1 0.0 0.0 0.6 0.3 0.0 0.0 0.7 0.0 0.0 43.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 6.1 3.3 1.8 33.7 18.6 0.0 0.0 0.3 0.4 1.1 0.0 0.1 3.6 7.5 0.0 1.8 0.0 8.5 1.7 0.1 0.0 0.0 0.1 0.9 0.0 0.1 1.5 10.0 0.0 0.0 0.6 0.0 0.2 0.5 2.8 0.0 0.2 0.0 0.0 0.3 RUNDC3A "RAP2IP, RPIP8" ENSG00000108309 "RUN domain containing 3A" Q59EK9 17 44308413-44318670 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 208.4;pituitary gland: 98.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 55.4;Early spermatids: 24.4;Enteroendocrine cells: 39.0;Excitatory neurons: 46.1;Horizontal cells: 32.0;Inhibitory neurons: 30.4;Late spermatids: 83.4" "Group enriched" "Detected in many" 5 "glioma: 8.6;pancreatic cancer: 3.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "SCLC-21H: 62.5;SH-SY5Y: 40.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023548, HPA070733" Enhanced Supported Enhanced Vesicles NA NA "Cluster 65: Brain - Ion transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" Vesicles "HPA023548: AB_1856069, HPA070733: AB_2732162" "unprognostic (3.66e-2)" "unprognostic (3.77e-2)" "unprognostic (3.50e-3)" "unprognostic (1.58e-3)" "unprognostic (3.04e-1)" "unprognostic (2.02e-1)" "unprognostic (3.87e-3)" "unprognostic (2.29e-1)" "unprognostic (4.63e-2)" "unprognostic (3.43e-2)" "unprognostic (1.42e-3)" "unprognostic (1.34e-1)" "unprognostic (8.87e-3)" "unprognostic (1.07e-2)" "unprognostic (5.17e-2)" "unprognostic (9.39e-2)" "unprognostic (1.84e-1)" 0.3 14.3 149.2 0.4 159.5 2.3 0.3 93.0 208.4 0.2 45.6 3.4 1.2 0.5 0.2 0.8 0.2 0.3 1.8 169.4 105.3 1.8 0.2 0.4 0.2 108.0 106.4 0.8 3.8 3.1 98.3 1.5 108.5 0.8 0.6 31.2 0.3 0.3 0.1 7.9 1.3 0.5 79.2 1.6 2.3 15.2 109.4 0.4 1.4 0.3 0.1 0.2 0.7 135.7 0.0 0.4 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.6 4.3 0.0 1.4 0.3 0.0 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 8.0 0.0 0.2 0.0 0.2 0.0 0.0 0.3 0.0 0.6 0.0 0.9 0.2 0.0 0.5 0.3 0.3 0.1 0.1 1.1 0.3 0.1 62.5 40.3 0.3 0.0 0.3 0.1 0.5 0.8 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.1 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 149.2 159.5 93.0 208.4 169.4 105.3 108.0 106.4 108.5 79.2 109.4 135.7 0.1 0.0 0.6 17.3 0.0 0.3 0.3 0.0 0.0 55.4 0.2 0.3 1.1 0.0 0.0 0.0 6.2 0.0 0.0 0.0 3.9 1.3 24.4 0.2 0.3 0.2 39.0 18.7 46.1 3.1 0.0 1.0 0.0 0.2 0.0 0.5 0.4 0.0 0.2 32.0 30.4 0.5 4.1 0.3 0.5 83.4 1.5 0.3 0.0 4.7 0.1 6.5 1.0 16.1 12.5 1.0 1.2 3.4 0.0 0.4 0.0 0.8 0.0 16.8 0.0 0.8 0.5 1.4 1.3 0.0 0.4 0.1 0.1 3.0 0.1 0.3 RXRA NR2B1 ENSG00000186350 "Retinoid X receptor alpha" P19793 9 134317098-134440585 "Cancer-related genes, FDA approved drug targets, Metabolic proteins, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 106.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 218.9;Kupffer cells: 134.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 19.5" "Group enriched" "Detected in many" 5 "granulocytes: 19.5;monocytes: 12.9" "Cell line enhanced" "Detected in many" "HaCaT: 105.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004565, CAB005352" Supported Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm "Golgi apparatus" "CAB004565: AB_2184877, CAB005352: AB_2184874" "unprognostic (2.68e-1)" "unprognostic (7.94e-2)" "unprognostic (3.67e-2)" "unprognostic (7.22e-2)" "unprognostic (2.07e-2)" "unprognostic (6.69e-2)" "unprognostic (1.52e-1)" "unprognostic (2.15e-1)" "unprognostic (3.45e-2)" "unprognostic (1.65e-3)" "prognostic favorable (7.02e-4)" "unprognostic (7.72e-2)" "prognostic unfavorable (5.58e-4)" "unprognostic (1.25e-2)" "unprognostic (2.58e-1)" "unprognostic (1.49e-2)" "unprognostic (2.59e-1)" 40.5 22.7 33.5 14.5 36.4 18.9 11.2 25.5 29.4 12.2 16.9 16.6 25.8 13.5 8.7 28.5 16.5 13.6 19.4 27.1 30.2 16.0 32.9 18.8 8.2 32.9 31.3 21.7 25.4 45.1 3.5 14.5 30.8 15.6 10.0 5.4 21.7 17.1 106.5 88.1 28.0 11.1 30.4 25.1 14.7 7.9 42.7 6.0 17.6 51.9 7.6 16.2 8.2 22.6 19.6 36.4 14.7 21.9 42.8 19.1 66.7 14.1 16.1 9.6 6.5 20.7 28.0 0.0 25.8 22.5 15.1 105.5 7.7 32.8 2.9 26.3 7.2 0.1 47.5 30.0 20.4 18.8 4.8 29.0 52.1 11.5 10.6 12.9 12.8 1.6 26.0 1.1 8.7 61.8 1.1 59.5 17.5 63.4 16.9 7.4 30.3 36.7 12.2 64.3 17.2 10.5 37.3 46.9 10.6 7.1 44.9 78.8 16.5 16.2 23.4 17.4 9.7 1.7 0.2 0.4 11.6 33.9 12.7 1.3 8.1 6.6 1.4 12.9 0.2 0.3 0.9 1.0 3.2 0.1 0.2 1.2 19.5 2.2 11.2 0.7 1.2 3.2 33.5 36.4 25.5 29.4 27.1 30.2 32.9 31.3 30.8 30.4 42.7 22.6 32.1 32.1 22.9 36.2 4.6 34.5 16.5 21.1 12.5 6.0 16.7 14.4 38.8 72.9 26.2 9.2 25.0 30.1 11.0 72.3 1.9 13.9 4.3 19.8 16.6 28.9 9.6 30.9 9.1 14.1 29.5 23.7 17.9 17.4 1.3 21.3 71.0 218.9 31.9 33.7 17.6 21.2 10.2 134.2 30.0 18.8 32.3 50.4 12.4 10.3 80.4 36.5 14.4 29.1 6.0 15.9 32.4 21.1 7.4 17.7 55.6 19.9 34.4 19.9 19.7 34.6 30.6 0.9 9.4 34.4 46.9 23.9 12.6 15.5 27.5 32.8 SCGB1D2 "LIPB, LPHB" ENSG00000124935 "Secretoglobin family 1D member 2" O95969 11 62242239-62244812 "Cancer-related genes, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "breast: 1227.2;cervix: 4002.8" "Group enriched" "Detected in some" 4 "Endometrial ciliated cells: 3242.1;Glandular and luminal cells: 3417.9" "Group enriched" "Detected in many" 6 "breast cancer: 625.1;endometrial cancer: 226.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "SCLC-21H: 10.4" HPA035318 Approved "Secreted in other tissues" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 44: Endometrium - Transcription" "HPA035318: AB_10610421" "unprognostic (8.76e-2)" "unprognostic (2.14e-1)" "prognostic favorable (3.46e-6)" "unprognostic (2.39e-2)" "unprognostic (5.89e-2)" "unprognostic (4.72e-2)" "unprognostic (1.99e-1)" "unprognostic (6.43e-2)" "prognostic favorable (8.03e-6)" "unprognostic (1.55e-1)" "unprognostic (1.15e-2)" 12.9 4.9 4.1 0.0 4.0 0.0 1227.2 3.2 5.4 4002.8 13.8 0.3 0.1 89.0 355.8 10.1 110.3 0.1 3.1 3.5 4.4 10.1 0.2 0.1 0.1 4.7 5.7 1.1 4.5 0.5 5.2 0.2 4.2 8.6 0.2 1.8 69.2 2.9 7.2 342.4 0.4 0.0 3.5 0.0 0.3 0.2 4.3 0.4 0.6 6.0 0.0 0.2 0.3 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 10.4 0.1 0.0 1.8 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 4.0 3.2 5.4 3.5 4.4 4.7 5.7 4.2 3.5 4.3 4.6 2.1 0.0 0.0 0.0 1.6 27.4 4.8 0.0 0.0 0.5 647.8 251.6 10.9 0.0 0.0 7.3 0.0 0.0 5.3 0.0 23.5 0.3 0.0 3242.1 409.9 12.0 0.0 0.0 0.0 0.2 0.0 3.6 0.0 3417.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 15.0 823.6 0.0 0.0 18.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.7 0.0 46.1 0.0 0.9 0.0 0.2 8.6 0.0 0.0 0.0 7.0 0.1 20.0 0.0 0.0 1.1 SCGB2A2 "MGB1, MGC71974, PSBP1, UGB2" ENSG00000110484 "Secretoglobin family 2A member 2" Q13296 11 62270158-62273160 "Cancer-related genes, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "breast: 2805.9;skin 1: 708.1" "Group enriched" "Detected in some" 11 "Breast glandular cells: 2119.6;Breast myoepithelial cells: 1028.8;Melanocytes: 1762.7" "Cancer enriched" "Detected in many" 23 "breast cancer: 823.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 124 "SK-BR-3: 18.0" CAB026270 Enhanced "Secreted in female reproductive system" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 35: Glandular cells - Unknown function" "CAB026270: AB_912980" "unprognostic (2.38e-1)" "unprognostic (7.28e-2)" "prognostic favorable (9.57e-8)" "unprognostic (4.17e-1)" "unprognostic (3.75e-1)" 34.4 0.2 0.0 0.0 0.0 0.0 2805.9 0.0 0.0 309.2 0.0 0.4 0.0 4.1 0.0 76.6 0.1 0.0 4.0 0.0 0.0 0.5 0.3 0.2 0.0 0.0 0.0 0.2 0.4 0.0 1.6 1.3 0.0 0.2 0.0 0.0 159.3 0.1 1.8 708.1 0.2 0.0 0.0 0.2 0.3 1.1 0.0 2.1 0.2 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 6.6 49.6 0.3 0.0 0.0 0.0 2119.6 1028.8 0.1 0.0 0.0 0.0 0.0 0.0 25.3 0.0 0.0 0.0 1.4 41.9 21.6 11.3 0.0 0.0 0.0 0.0 0.0 6.7 0.0 141.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.4 0.1 0.0 3.2 1762.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 10.9 0.0 9.2 0.0 0.0 0.0 SEC14L3 TAP2 ENSG00000100012 "SEC14 like lipid binding 3" Q9UDX4 22 30447959-30472017 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 3.8;liver: 2.9;retina: 9.0" "Group enriched" "Detected in some" 8 "Muller glia cells: 27.6;Respiratory ciliated cells: 22.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA059450 Uncertain NA NA "Cluster 77: Retina - Visual perception" "Cluster 5: Muller glia cells - Visual perception" "HPA059450: AB_2684024" "unprognostic (2.42e-1)" "unprognostic (2.56e-1)" "unprognostic (1.42e-1)" "unprognostic (5.35e-2)" "unprognostic (2.00e-4)" "unprognostic (3.62e-3)" "unprognostic (6.68e-2)" "unprognostic (3.19e-1)" "unprognostic (2.41e-10)" "unprognostic (1.27e-1)" "unprognostic (2.09e-1)" "unprognostic (4.10e-1)" 0.0 0.1 0.2 0.1 0.1 3.8 0.0 0.3 0.3 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.2 0.0 0.0 2.9 1.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 9.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.0 1.7 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.3 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.1 0.1 0.0 0.1 0.1 0.3 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.2 0.2 0.0 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.4 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.3 0.3 0.2 0.0 0.2 0.0 0.2 0.0 0.1 0.4 0.1 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 3.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 2.7 0.2 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 27.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 22.3 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SEC14L4 "dJ130H16.5, TAP3" ENSG00000133488 "SEC14 like lipid binding 4" Q9UDX3 22 30488902-30505711 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 8.2;liver: 19.3" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 22.4;Alveolar cells type 2: 6.9;Cholangiocytes: 11.5;Erythroid cells: 26.5;Hepatocytes: 22.8" "Cancer enhanced" "Detected in many" "liver cancer: 4.3" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Lineage enriched" "Detected in single" 7 "granulocytes: 1.0" "Cell line enriched" "Detected in some" 4 "BEWO: 37.7" "Region enhanced" "Detected in single" "thalamus: 1.2" HPA069748 Approved Centrosome NA NA 82000 "Cluster 6: Non-specific - Transcription" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 6: Erythroid cells - Oxygen transport" Centrosome "HPA069748: AB_2686187" "unprognostic (6.98e-4)" "unprognostic (2.72e-2)" "unprognostic (2.40e-2)" "unprognostic (1.03e-3)" "unprognostic (6.78e-2)" "unprognostic (2.07e-2)" "unprognostic (9.88e-2)" "unprognostic (4.93e-2)" "unprognostic (3.34e-2)" "unprognostic (1.56e-2)" "unprognostic (1.88e-2)" "unprognostic (8.87e-2)" "unprognostic (4.06e-8)" "unprognostic (1.69e-1)" "unprognostic (1.64e-1)" "unprognostic (2.28e-1)" "unprognostic (5.98e-2)" 0.1 0.9 0.5 0.1 0.5 8.2 0.2 0.5 0.5 0.5 0.5 0.0 0.1 0.1 0.0 0.0 0.2 0.1 0.0 0.3 0.3 0.2 19.3 4.4 0.1 0.5 0.5 0.2 0.2 3.3 0.1 0.2 0.5 0.1 0.0 0.4 0.1 0.0 0.0 0.7 0.1 0.1 0.4 0.2 0.5 4.4 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.8 2.3 7.1 0.0 0.0 0.0 0.0 37.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.1 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.1 0.1 0.3 2.5 0.0 0.1 0.0 0.1 0.1 0.2 0.1 9.2 0.4 0.1 0.0 0.0 0.0 0.2 0.1 0.1 2.4 0.1 0.0 0.1 0.0 0.1 0.1 0.1 1.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.1 0.0 0.1 0.0 0.0 0.5 0.5 0.5 0.5 0.3 0.3 0.5 0.5 0.5 0.4 0.6 0.8 0.3 22.4 6.9 0.7 0.1 0.1 0.5 0.3 0.0 0.4 0.2 0.3 0.7 11.5 1.4 1.8 0.0 0.1 1.3 0.0 0.0 0.5 0.7 1.8 0.2 0.2 0.0 26.5 0.4 0.0 0.4 0.3 0.0 0.2 1.3 0.2 0.4 22.8 0.1 1.7 0.4 0.2 0.0 0.3 0.3 0.1 0.6 0.4 0.0 0.0 0.1 5.3 0.0 0.5 0.1 0.1 0.0 0.0 0.0 0.5 0.0 0.0 4.3 0.9 0.0 0.9 0.1 0.3 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.6 SEC14L6 ENSG00000214491 "SEC14 like lipid binding 6" B5MCN3 22 30522799-30546682 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "epididymis: 21.2;parathyroid gland: 30.5" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 12.8;Alveolar cells type 2: 10.5;Cholangiocytes: 11.5;Collecting duct cells: 12.9;Ductal cells: 6.6;Muller glia cells: 18.6" "Cancer enriched" "Detected in many" 7 "renal cancer: 12.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "K-562: 12.3;RPTEC TERT1: 21.8;SiHa: 6.6" HPA067695 Approved Nucleoplasm NA NA "Cluster 35: T-regs - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 5: Muller glia cells - Visual perception" Nucleoplasm "HPA067695: AB_2685889" "unprognostic (3.49e-2)" "unprognostic (4.76e-2)" "unprognostic (4.79e-2)" "unprognostic (4.09e-2)" "unprognostic (3.04e-2)" "unprognostic (1.12e-1)" "unprognostic (7.28e-3)" "unprognostic (3.88e-2)" "unprognostic (3.13e-1)" "unprognostic (3.35e-1)" "unprognostic (1.29e-1)" "unprognostic (9.25e-2)" "unprognostic (8.69e-2)" "unprognostic (8.20e-2)" "unprognostic (2.12e-1)" "unprognostic (2.48e-2)" "unprognostic (6.02e-2)" 1.4 1.4 5.3 0.3 4.6 2.1 3.9 4.5 4.7 3.5 5.9 0.5 0.6 3.2 21.2 0.3 1.7 4.5 0.3 4.4 5.0 8.4 0.4 11.9 0.4 8.6 6.2 2.4 5.5 30.5 2.5 0.5 8.8 1.7 0.3 5.0 0.4 2.6 0.2 10.0 0.5 2.2 5.2 0.4 1.2 5.4 8.7 0.3 0.3 0.8 0.6 0.4 0.4 4.9 0.2 0.1 0.9 0.3 0.0 0.0 1.0 0.1 0.0 0.1 0.0 0.2 0.5 0.3 1.1 0.1 0.1 0.2 0.1 0.0 0.3 0.0 0.0 3.0 0.3 0.3 0.1 0.2 0.4 0.0 0.1 0.1 0.1 0.7 0.0 0.1 12.3 0.2 0.0 0.5 0.1 0.4 0.5 0.0 0.1 0.2 0.0 0.1 21.8 0.2 0.2 0.1 6.6 0.1 0.0 0.2 1.8 0.0 0.0 0.2 0.1 0.2 0.1 0.1 0.1 0.2 0.0 0.3 0.1 0.5 0.1 0.1 0.1 0.1 0.3 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.4 0.3 0.1 0.1 0.5 0.0 5.3 4.6 4.5 4.7 4.4 5.0 8.6 6.2 8.8 5.2 8.7 4.9 0.0 12.8 10.5 0.3 0.2 0.1 0.5 0.0 0.0 0.2 0.4 0.5 0.3 11.5 3.7 12.9 0.0 0.0 0.0 0.0 1.9 6.6 0.0 0.3 0.4 1.0 0.0 0.0 0.7 0.8 0.0 0.2 0.0 1.5 1.3 0.2 0.7 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.3 0.3 0.1 0.0 0.0 0.6 18.6 0.0 1.5 0.6 1.8 0.0 0.7 0.0 0.1 0.0 2.9 0.0 0.5 0.0 2.7 0.1 0.9 0.4 0.0 0.0 0.1 0.9 0.0 0.0 0.2 SEMA3F "Sema4, SEMAK" ENSG00000001617 "Semaphorin 3F" Q13275 3 50155045-50189075 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 100.8" "Cell type enhanced" "Detected in many" "Adipocytes: 40.2;Bipolar cells: 23.4;Endothelial cells: 24.4;Hepatic stellate cells: 25.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 108.1;HUVEC TERT2: 187.0;RT4: 112.3;SK-BR-3: 170.2;TIME: 338.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA035008 Approved "Secreted to blood" NA NA 1700000 7900000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA035008: AB_10604091" "unprognostic (8.17e-2)" "unprognostic (2.01e-1)" "unprognostic (1.12e-2)" "unprognostic (1.87e-2)" "unprognostic (5.52e-3)" "unprognostic (1.71e-1)" "prognostic unfavorable (5.15e-4)" "unprognostic (1.71e-1)" "unprognostic (9.05e-2)" "unprognostic (4.20e-1)" "unprognostic (9.55e-2)" "unprognostic (3.01e-1)" "unprognostic (2.23e-2)" "unprognostic (6.19e-2)" "unprognostic (8.56e-2)" "unprognostic (3.88e-3)" "unprognostic (6.87e-3)" 33.8 9.0 8.8 8.6 5.7 2.7 31.9 5.1 8.1 28.3 12.0 10.5 13.4 14.5 5.4 100.8 15.6 10.8 22.6 5.0 9.2 49.2 4.8 46.2 3.7 10.2 12.7 3.6 6.7 5.5 11.1 30.4 8.7 32.7 6.3 22.0 24.6 32.5 10.4 75.1 12.5 9.1 6.3 50.7 17.3 2.4 21.8 6.1 27.1 6.1 12.6 27.0 55.4 4.7 13.9 3.1 0.7 14.2 0.2 1.3 3.0 8.0 24.2 6.5 10.2 5.4 6.1 0.5 77.9 1.1 0.7 47.5 6.9 100.7 2.4 0.1 1.8 0.8 108.1 18.5 5.7 1.7 3.2 6.2 55.3 15.1 45.4 90.7 187.0 1.2 2.9 0.1 1.3 12.4 1.5 7.5 8.6 6.2 10.1 11.8 0.0 0.5 7.2 112.3 1.1 2.6 12.8 170.2 0.3 10.4 67.2 7.3 338.6 4.2 31.9 29.7 5.5 0.2 0.0 0.9 0.3 4.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.8 5.7 5.1 8.1 5.0 9.2 10.2 12.7 8.7 6.3 21.8 4.7 40.2 0.0 1.1 0.0 0.2 6.8 3.0 9.2 5.7 23.4 10.7 6.0 9.2 1.5 6.6 18.4 10.4 11.2 0.6 5.5 0.0 0.3 0.0 6.5 2.4 24.4 0.0 0.0 0.7 0.8 0.5 1.1 16.3 6.9 0.0 0.2 25.4 0.6 1.4 6.7 1.1 10.7 0.0 0.3 0.8 0.3 0.3 0.2 0.0 3.7 0.0 8.7 0.0 0.0 0.1 6.8 3.8 0.0 0.0 2.5 5.7 0.7 5.4 19.8 0.0 0.5 2.5 0.0 0.4 17.7 8.9 6.3 0.4 0.2 5.2 8.6 SEMA7A "CD108, H-Sema-L, SEMAL" ENSG00000138623 "Semaphorin 7A (John Milton Hagen blood group)" O75326 15 74409289-74433958 "Blood group antigen proteins, CD markers, Plasma proteins, Predicted membrane proteins" "Differentiation, Inflammatory response, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 60.1;retina: 34.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 68.8;Extravillous trophoblasts: 58.8;Granulosa cells: 65.1;Pancreatic endocrine cells: 91.0;Rod photoreceptor cells: 58.3;Syncytiotrophoblasts: 166.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 1.8;eosinophil: 3.1" "Lineage enriched" "Detected in single" 5 "granulocytes: 3.1" "Cell line enhanced" "Detected in many" "HMC-1: 275.8;hTEC/SVTERT24-B: 108.7;U-251 MG: 166.3;U-87 MG: 92.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008210, HPA042273" Uncertain Uncertain Vesicles NA NA 38000000 "Cluster 52: Eosinophils - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Vesicles "HPA008210: , HPA042273: AB_10806234" "unprognostic (2.00e-1)" "unprognostic (2.72e-1)" "unprognostic (2.02e-2)" "unprognostic (5.81e-2)" "unprognostic (6.49e-2)" "unprognostic (8.61e-2)" "unprognostic (2.54e-2)" "unprognostic (4.18e-3)" "unprognostic (1.33e-1)" "unprognostic (1.39e-1)" "unprognostic (5.18e-3)" "unprognostic (1.44e-1)" "prognostic unfavorable (2.45e-11)" "unprognostic (1.32e-1)" "unprognostic (2.01e-2)" "unprognostic (6.25e-2)" "unprognostic (2.57e-2)" 2.0 2.5 4.6 7.0 11.0 9.9 1.9 19.1 14.4 2.2 0.9 2.4 1.5 2.9 0.9 4.8 1.4 1.8 2.3 5.1 8.2 2.8 1.6 8.1 13.2 19.9 11.6 7.8 0.9 1.9 2.7 16.3 22.9 1.8 0.9 34.6 2.2 1.2 2.0 8.5 10.8 1.1 10.6 60.1 3.5 29.5 17.2 9.4 1.3 0.3 12.9 8.2 2.5 20.2 16.7 0.2 4.8 1.4 6.0 20.1 39.7 75.2 30.1 15.5 23.8 6.5 26.6 0.1 4.3 34.2 12.6 4.9 1.5 4.8 16.0 1.3 0.9 30.0 0.1 8.3 1.3 0.9 275.8 14.3 0.2 108.7 6.0 39.0 0.2 2.0 17.5 10.1 51.2 1.4 4.3 9.9 5.2 0.4 11.3 0.6 3.3 4.4 6.5 7.1 0.3 0.5 0.5 13.4 6.1 4.1 1.0 6.0 3.0 28.8 19.2 14.1 166.3 1.8 1.3 0.3 92.4 3.4 1.5 1.8 0.0 3.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 4.6 11.0 19.1 14.4 5.1 8.2 19.9 11.6 22.9 10.6 17.2 20.2 1.8 3.2 0.0 1.0 22.6 0.4 1.6 3.1 0.6 13.7 1.2 1.3 1.4 0.0 4.0 1.8 68.8 25.6 5.2 0.6 0.0 19.8 0.5 4.6 1.5 5.3 0.0 21.7 12.4 13.9 58.8 1.8 1.5 10.6 8.2 65.1 0.7 0.7 7.2 1.7 5.9 0.0 0.0 0.3 12.0 2.5 3.7 4.8 8.8 0.0 28.6 6.8 1.0 4.0 16.3 91.0 0.1 1.9 6.4 3.3 0.1 0.1 2.0 58.3 0.0 0.2 9.0 0.9 0.8 0.2 1.4 166.4 5.7 22.0 0.0 24.4 SGK2 ENSG00000101049 "Serum/glucocorticoid regulated kinase 2" Q9HBY8 20 43558968-43588237 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 40.5;kidney: 53.6;liver: 63.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 76.5;Distal tubular cells: 76.3;Hepatocytes: 32.8;Paneth cells: 21.7;Proximal enterocytes: 23.8;Proximal tubular cells: 25.5" "Cancer enhanced" "Detected in many" "liver cancer: 8.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 20.5;CAPAN-2: 14.2;Hep G2: 18.7;OE19: 61.7;RPTEC TERT1: 25.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA008859, HPA011387" Uncertain Supported Nucleoplasm NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA008859: AB_2668159, HPA011387: AB_1856744" "unprognostic (1.82e-1)" "unprognostic (1.84e-1)" "unprognostic (4.53e-2)" "unprognostic (2.86e-1)" "unprognostic (6.27e-2)" "unprognostic (2.98e-4)" "unprognostic (2.05e-2)" "unprognostic (1.35e-1)" "unprognostic (4.30e-2)" "unprognostic (2.60e-1)" "unprognostic (1.05e-1)" "unprognostic (5.72e-4)" "unprognostic (4.15e-2)" "unprognostic (1.38e-1)" "unprognostic (2.56e-1)" "unprognostic (3.11e-2)" "prognostic favorable (5.65e-4)" 23.5 1.4 4.9 1.5 14.8 0.5 6.1 12.6 10.5 3.5 0.7 37.7 31.6 1.8 33.8 1.0 3.7 10.0 1.2 6.0 7.7 53.6 63.2 1.0 0.2 18.1 13.3 6.6 16.2 0.5 3.0 0.8 14.3 2.6 40.5 5.6 1.8 2.9 0.4 6.2 20.1 1.6 11.8 1.1 22.8 1.8 13.3 0.3 1.7 0.4 0.3 4.2 3.0 24.5 0.0 20.5 0.3 0.1 0.3 0.0 0.1 0.2 0.0 0.2 0.0 0.6 14.2 0.1 8.7 0.1 0.1 0.2 0.0 0.0 0.2 0.0 0.3 0.4 0.0 18.7 0.4 0.0 0.1 0.0 0.5 0.0 0.0 0.7 0.0 0.4 0.2 0.1 0.0 0.1 0.1 0.5 0.1 61.7 0.0 0.1 0.1 0.0 25.4 4.2 0.2 1.0 0.0 1.2 0.1 0.4 0.0 0.1 0.9 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.2 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 14.8 12.6 10.5 6.0 7.7 18.1 13.3 14.3 11.8 13.3 24.5 0.3 0.0 0.0 4.9 0.2 0.1 0.1 0.2 0.0 0.8 0.3 0.8 4.9 8.6 0.0 11.0 0.0 5.1 0.0 76.5 76.3 6.8 0.3 0.9 0.5 0.6 1.8 0.0 0.7 6.3 1.3 0.4 11.2 2.4 0.0 0.7 0.7 32.8 0.7 6.7 1.3 4.1 0.0 1.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.2 0.0 3.5 20.7 2.5 21.7 0.4 0.0 0.1 23.8 25.5 0.2 0.8 0.0 0.2 0.4 0.1 0.1 0.0 0.1 17.1 0.2 0.0 7.7 0.3 SGO1 "NY-BR-85, SGOL1" ENSG00000129810 "Shugoshin 1" Q5FBB7 3 20160593-20186206 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 8.7;lymphoid tissue: 13.0;testis: 6.7" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 16.5;Extravillous trophoblasts: 42.6;Granulosa cells: 20.3;Hofbauer cells: 10.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 5 "basophil: 10.0;memory B-cell: 8.8;naive B-cell: 8.9;plasmacytoid DC: 4.1;T-reg: 2.6" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035501, HPA069302, HPA069857" Enhanced Enhanced Nucleoplasm,Kinetochore,Cytosol Yes Yes "Cluster 37: B-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Kinetochore, Cytosol" "HPA035501: AB_2732469, HPA069302: , HPA069857: AB_2686214" "unprognostic (6.87e-3)" "unprognostic (5.01e-2)" "unprognostic (2.25e-2)" "unprognostic (8.93e-3)" "unprognostic (2.51e-2)" "unprognostic (4.10e-2)" "unprognostic (2.55e-6)" "unprognostic (9.49e-3)" "unprognostic (2.45e-2)" "unprognostic (3.69e-2)" "unprognostic (1.65e-4)" "unprognostic (1.52e-2)" "unprognostic (0.00e+0)" "unprognostic (2.29e-2)" "unprognostic (4.95e-2)" "unprognostic (4.14e-1)" "unprognostic (1.64e-1)" 0.3 0.1 0.3 3.3 0.7 8.7 0.5 0.9 0.5 0.4 0.0 2.1 2.3 0.4 0.0 1.9 0.1 0.4 0.1 0.3 0.4 0.3 0.6 0.3 6.2 0.8 0.6 0.2 0.1 0.2 0.0 1.7 0.6 0.2 2.8 0.1 0.4 0.1 0.1 1.1 2.5 1.0 0.3 1.4 1.5 6.7 0.6 13.0 0.2 0.0 6.6 0.9 0.7 1.2 20.3 23.9 29.9 18.5 1.4 2.6 20.2 21.3 10.1 31.2 33.6 16.5 24.0 30.7 10.6 8.6 21.2 11.4 28.7 11.3 37.6 40.9 19.6 34.6 15.6 12.8 0.2 32.0 28.8 0.3 0.9 33.3 13.1 4.0 18.5 34.9 31.3 52.2 24.6 19.4 52.4 15.4 30.0 20.3 17.0 31.8 38.4 17.7 7.5 14.9 14.2 15.4 23.6 27.2 13.1 22.7 18.2 21.3 4.7 22.5 27.3 20.5 43.3 22.8 57.4 35.2 12.5 31.1 35.0 10.0 0.1 1.4 0.2 0.2 0.1 8.8 0.6 0.7 0.3 8.9 0.2 0.3 1.4 0.3 0.2 4.1 2.6 0.6 0.3 0.7 0.9 0.5 0.3 0.4 0.8 0.6 0.6 0.3 0.6 1.2 0.1 0.0 0.5 0.0 1.9 0.0 0.0 0.0 0.0 0.0 2.0 3.4 0.0 0.0 0.0 1.8 0.0 16.5 1.5 0.0 0.0 1.1 0.0 2.3 1.6 1.2 0.0 0.0 0.0 1.8 42.6 3.3 0.0 2.9 1.3 20.3 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 2.6 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.3 0.0 0.0 1.1 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 4.9 1.0 4.3 0.0 0.0 SGO2 "FLJ25211, SGOL2, TRIPIN" ENSG00000163535 "Shugoshin 2" Q562F6 2 200510008-200584096 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Meiosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 14.9;testis: 32.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 11.6;Endometrial ciliated cells: 12.1;Extravillous trophoblasts: 31.0;granulocytes: 11.4;Granulosa cells: 23.4;Hofbauer cells: 13.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "basophil: 16.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 16.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035163, HPA040817" Enhanced Enhanced "Nucleoplasm,Nuclear bodies" NA Yes "Cluster 34: Basophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nuclear bodies" "HPA035163: AB_10602397, HPA040817: AB_2677149" "unprognostic (3.43e-1)" "unprognostic (1.70e-1)" "unprognostic (7.06e-3)" "unprognostic (6.71e-3)" "unprognostic (1.90e-1)" "unprognostic (1.77e-1)" "unprognostic (7.55e-6)" "unprognostic (1.12e-2)" "unprognostic (1.98e-3)" "unprognostic (4.87e-2)" "unprognostic (1.37e-4)" "unprognostic (9.49e-2)" "unprognostic (8.07e-9)" "unprognostic (5.21e-2)" "unprognostic (5.43e-2)" "unprognostic (9.86e-2)" "unprognostic (2.02e-1)" 3.3 0.9 0.6 4.4 0.9 6.8 1.9 0.8 0.9 0.9 0.3 3.1 2.5 1.8 0.7 2.4 1.4 1.2 1.0 0.5 0.9 0.9 0.8 1.5 7.9 0.9 0.9 1.9 0.5 1.1 0.3 2.6 0.9 1.4 3.2 0.9 0.7 0.7 0.4 2.3 2.6 2.0 0.7 2.0 1.8 32.6 0.9 14.9 1.2 0.6 8.1 1.5 0.9 1.2 34.6 16.2 37.0 17.4 5.2 7.9 23.7 38.7 16.6 32.0 33.1 24.3 23.5 22.5 18.6 18.1 34.4 25.3 33.6 20.1 54.5 48.0 16.9 43.5 21.6 17.5 1.6 43.9 33.1 3.4 2.5 32.9 17.3 8.0 29.4 31.3 33.1 31.6 61.4 15.4 35.9 17.9 26.7 24.9 41.2 28.8 49.1 21.3 13.3 13.6 22.2 15.4 28.6 13.3 16.3 29.2 14.1 25.2 18.1 33.9 34.0 31.6 34.0 14.3 33.5 49.8 21.4 28.9 49.4 16.7 1.4 4.5 2.2 1.4 1.4 2.7 2.4 2.2 0.8 3.2 1.8 2.2 1.0 2.0 1.7 1.7 3.6 1.2 0.6 0.9 0.8 0.9 0.5 0.9 0.9 0.9 0.9 0.7 0.9 1.2 9.4 3.2 3.2 0.0 1.2 0.0 0.0 0.0 0.0 0.0 5.8 7.1 0.0 0.0 6.2 0.0 0.0 11.6 7.8 0.0 3.9 3.9 0.0 12.1 5.3 3.3 0.0 0.0 0.0 2.7 31.0 6.7 0.0 3.6 11.4 23.4 0.0 0.0 13.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 1.6 0.0 0.0 0.0 0.0 3.2 0.0 0.0 1.7 0.0 0.0 2.5 8.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 3.4 3.8 4.0 0.0 0.0 SKA1 "C18orf24, MGC10200" ENSG00000154839 "Spindle and kinetochore associated complex subunit 1" Q96BD8 18 50375040-50394168 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 12.0;lymphoid tissue: 4.9" "Cell type enhanced" "Detected in many" "Erythroid cells: 22.3;Extravillous trophoblasts: 9.2;Plasma cells: 10.0;Spermatocytes: 16.7;Spermatogonia: 13.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "Karpas-707: 82.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA045495 Approved Approved Microtubules NA Yes "Cluster 17: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 2: Karpas-707 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" Microtubules "HPA045495: AB_10960405" "unprognostic (2.18e-2)" "unprognostic (7.85e-3)" "unprognostic (7.66e-3)" "unprognostic (5.93e-3)" "unprognostic (1.91e-1)" "unprognostic (1.25e-1)" "prognostic unfavorable (9.60e-8)" "unprognostic (1.03e-3)" "unprognostic (1.16e-2)" "unprognostic (1.20e-2)" "unprognostic (1.18e-4)" "unprognostic (3.91e-3)" "unprognostic (0.00e+0)" "unprognostic (4.50e-3)" "unprognostic (4.66e-2)" "unprognostic (2.22e-2)" "unprognostic (1.79e-1)" 0.4 0.5 0.9 2.2 0.8 12.0 0.3 2.5 1.1 0.4 0.8 1.6 1.7 0.6 0.2 2.5 0.2 0.3 0.2 1.0 0.5 0.1 0.3 0.4 4.9 1.0 0.9 0.2 0.4 0.1 0.0 1.6 1.2 0.3 2.1 0.4 0.3 0.1 0.6 1.5 1.4 1.1 0.3 1.3 0.8 4.3 1.3 3.6 0.3 0.2 4.8 0.5 0.7 2.4 27.1 10.8 18.6 19.0 1.2 2.1 9.9 30.7 10.6 29.9 28.5 4.7 10.6 21.1 7.6 11.0 25.8 23.6 25.6 13.0 31.4 34.6 2.6 27.0 5.5 18.3 2.3 42.2 26.8 1.5 1.3 20.7 8.2 3.2 20.0 20.0 30.8 82.6 26.4 5.7 34.6 12.1 14.2 6.5 6.4 17.3 18.3 23.5 8.5 1.6 13.7 10.9 17.2 9.9 13.6 15.3 11.4 20.2 10.1 32.8 19.0 12.8 31.8 27.5 41.6 32.4 18.2 34.9 33.3 0.9 0.4 0.1 0.1 0.1 0.1 0.2 0.1 0.5 0.2 0.3 0.2 0.1 0.6 0.6 0.2 0.2 0.4 0.2 0.9 0.8 2.5 1.1 1.0 0.5 1.0 0.9 1.2 0.3 1.3 2.4 0.2 0.0 2.2 0.0 2.8 1.0 0.2 0.4 0.0 0.4 0.7 0.6 0.4 0.0 0.8 0.0 2.1 4.4 0.7 1.6 0.0 0.1 4.5 0.5 0.7 0.4 1.2 22.3 0.2 0.0 9.2 1.4 0.5 1.1 0.0 4.9 2.2 0.1 5.3 0.0 0.1 2.7 0.0 0.8 0.9 2.2 0.3 0.6 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.2 1.1 0.0 10.0 0.4 0.1 0.1 0.2 0.8 0.0 0.2 1.4 16.7 13.5 3.7 0.3 1.5 1.4 0.5 3.4 1.0 SKA3 "C13orf3, MGC4832, RAMA1" ENSG00000165480 "Spindle and kinetochore associated complex subunit 3" Q8IX90 13 21153595-21176552 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 4.7;lymphoid tissue: 12.1;testis: 6.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 12.8;Extravillous trophoblasts: 21.0;Spermatocytes: 21.7;Spermatogonia: 18.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA039272, HPA039356, HPA061534" Approved Supported "Mitotic spindle,Centrosome,Cytosol" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Mitotic spindle" "Centrosome, Cytosol" "HPA039272: AB_10805359, HPA039356: AB_10805475, HPA061534: " "unprognostic (3.46e-2)" "unprognostic (7.21e-2)" "unprognostic (2.15e-1)" "unprognostic (1.62e-2)" "unprognostic (2.04e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (9.73e-6)" "unprognostic (2.03e-3)" "prognostic unfavorable (8.71e-4)" "unprognostic (2.03e-1)" "prognostic unfavorable (3.77e-4)" "unprognostic (1.39e-2)" "unprognostic (0.00e+0)" "unprognostic (2.24e-3)" "unprognostic (1.81e-1)" "unprognostic (1.22e-1)" "unprognostic (1.32e-1)" 0.2 0.1 0.2 2.5 0.2 4.7 0.8 0.1 0.3 0.2 0.0 1.7 1.0 0.5 0.0 1.9 0.2 0.4 0.0 0.5 0.2 0.1 0.2 0.2 4.3 0.2 0.2 0.0 0.0 0.0 0.0 1.6 0.2 0.0 3.0 0.0 0.2 0.0 0.0 1.8 2.1 1.1 0.2 0.7 1.0 6.3 0.3 12.1 0.1 0.1 3.7 0.4 0.5 0.2 26.1 13.0 25.8 20.5 0.9 5.1 19.1 35.0 14.8 42.1 28.7 23.4 27.8 35.6 10.0 19.3 18.5 24.4 34.4 15.2 54.7 30.3 15.9 47.3 7.7 12.7 0.0 39.5 17.7 1.5 1.0 34.9 15.4 4.2 20.7 30.6 26.3 14.2 33.9 21.0 60.7 37.8 27.9 42.8 23.8 36.5 50.3 15.8 12.2 9.9 30.1 11.1 11.8 17.1 8.1 17.9 15.3 33.5 8.7 16.0 23.8 17.0 43.9 9.0 19.7 34.5 4.4 31.1 51.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.5 0.1 0.2 0.2 0.1 0.3 0.5 0.2 0.2 0.2 0.2 0.2 0.3 0.2 0.4 0.0 0.0 0.0 2.6 2.0 0.7 2.4 0.0 0.1 0.9 0.8 0.8 0.0 1.8 0.0 0.0 8.7 1.0 2.1 0.0 1.2 6.3 2.8 0.9 1.4 0.0 12.8 0.8 1.3 21.0 2.1 1.5 1.6 0.0 5.8 1.8 0.4 5.5 0.0 0.6 1.8 2.0 1.9 2.9 7.7 1.5 1.6 0.0 1.9 0.8 0.3 3.1 0.0 0.2 1.0 1.6 1.2 8.5 0.3 0.4 0.6 2.0 0.4 0.0 0.3 2.3 21.7 18.2 5.8 2.8 2.2 1.2 0.5 5.0 0.7 SLC12A2 "BSC, BSC2, NKCC1, PPP1R141" ENSG00000064651 "Solute carrier family 12 member 2" P55011 5 128083766-128189677 "FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Symport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 75.6" "Cell type enhanced" "Detected in all" "Intestinal goblet cells: 480.6;Oligodendrocytes: 566.6;Undifferentiated cells: 370.0" "Cancer enhanced" "Detected in all" "colorectal cancer: 54.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 6.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "OE19: 153.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020130, HPA063697" Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" Vesicles "Plasma membrane" "HPA020130: AB_1854502, HPA063697: AB_2685094" "unprognostic (4.61e-2)" "unprognostic (2.63e-1)" "unprognostic (4.20e-3)" "prognostic favorable (8.60e-4)" "unprognostic (3.99e-1)" "unprognostic (5.65e-3)" "unprognostic (1.44e-3)" "unprognostic (1.81e-1)" "unprognostic (3.30e-1)" "unprognostic (2.95e-2)" "unprognostic (7.22e-2)" "unprognostic (1.39e-1)" "prognostic favorable (7.09e-4)" "unprognostic (1.63e-1)" "unprognostic (2.30e-1)" "unprognostic (3.79e-1)" "unprognostic (3.88e-3)" 8.4 17.5 15.0 10.8 48.4 4.4 43.9 46.3 23.2 7.2 40.4 48.5 41.7 8.4 2.4 4.6 6.0 39.4 6.1 13.5 31.1 6.6 4.2 10.3 5.6 40.8 43.1 5.4 6.1 14.7 5.5 4.9 38.6 23.5 58.9 16.8 75.6 2.6 15.4 28.4 49.1 10.2 27.1 4.5 61.8 8.0 32.4 4.1 8.6 8.3 6.0 7.3 3.5 64.8 13.5 65.3 65.8 25.6 16.1 10.4 13.6 12.2 9.1 8.6 8.9 26.4 20.9 19.9 16.1 10.6 7.8 39.5 12.7 14.0 13.2 20.0 15.8 5.7 11.4 3.8 4.9 7.3 9.5 11.1 5.0 19.1 11.2 6.4 14.2 8.5 9.4 13.2 13.4 14.2 13.0 6.1 7.7 153.6 21.1 7.1 18.5 8.2 10.0 45.0 11.5 7.3 24.6 10.6 9.9 7.0 5.9 3.7 24.1 21.2 14.2 16.3 15.7 11.0 10.7 21.6 11.2 4.2 17.6 0.3 0.4 0.2 1.1 0.7 1.9 1.7 1.0 1.4 0.6 2.1 1.1 1.6 0.2 2.4 0.5 6.4 1.1 0.3 15.0 48.4 46.3 23.2 13.5 31.1 40.8 43.1 38.6 27.1 32.4 64.8 38.3 16.0 46.2 23.8 20.5 22.9 20.1 44.9 10.8 76.6 186.9 86.7 18.0 137.2 52.1 33.1 127.2 1.4 34.4 48.2 1.9 68.6 55.8 33.1 43.1 44.2 74.4 2.5 160.6 48.2 2.7 21.3 199.3 38.4 18.4 28.8 12.8 8.8 4.2 80.8 73.2 480.6 57.0 8.6 12.0 95.3 85.4 11.4 204.5 105.9 2.5 22.6 11.3 55.3 566.6 50.1 60.6 29.0 20.2 131.6 38.8 10.6 19.6 86.4 72.3 33.9 64.3 29.1 27.1 14.9 30.0 1.4 21.1 14.1 370.0 21.5 SLC13A2 NaDC-1 ENSG00000007216 "Solute carrier family 13 member 2" Q13183 17 28473293-28497781 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "intestine: 119.6;kidney: 38.2;salivary gland: 44.9" "Group enriched" "Detected in some" 6 "Proximal enterocytes: 290.2;Proximal tubular cells: 97.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA014963 Enhanced NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA014963: AB_1857096" "unprognostic (8.47e-2)" "unprognostic (7.63e-3)" "unprognostic (4.36e-3)" "unprognostic (2.06e-1)" "unprognostic (2.36e-3)" "unprognostic (3.06e-1)" "unprognostic (2.28e-4)" "unprognostic (1.50e-1)" "unprognostic (1.74e-1)" "unprognostic (1.00e-2)" "prognostic favorable (9.00e-4)" "unprognostic (2.16e-1)" "unprognostic (2.64e-1)" "unprognostic (1.50e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.7 6.1 119.6 0.0 3.0 0.0 0.0 6.8 0.0 0.0 0.0 38.2 0.5 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.8 0.8 44.9 11.4 0.0 3.1 90.8 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.8 0.0 0.0 13.7 10.9 0.6 27.1 1.6 3.7 12.5 0.0 0.7 29.3 9.8 0.7 0.0 0.0 0.0 0.2 4.8 0.0 0.1 7.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 31.4 0.0 0.0 0.4 0.0 0.0 0.7 1.8 0.0 0.0 0.1 0.0 0.0 0.0 0.2 15.7 0.0 0.0 0.0 290.2 97.8 0.3 0.4 0.0 0.0 0.2 0.4 0.2 0.0 0.0 0.0 0.5 0.0 25.8 0.5 SLC14A1 "HsT1341, JK, RACH1, RACH2" ENSG00000141469 "Solute carrier family 14 member 1 (Kidd blood group)" Q13336 18 45687025-45752520 "Blood group antigen proteins, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Blood group antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 133.8;prostate: 78.3;urinary bladder: 90.9" "Group enriched" "Detected in many" 7 "Adipocytes: 136.6;Astrocytes: 228.5;Basal prostatic cells: 313.4;Erythroid cells: 102.5;Prostatic glandular cells: 192.6;Urothelial cells: 249.9" "Group enriched" "Detected in many" 5 "glioma: 5.3;prostate cancer: 8.6;urothelial cancer: 16.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 4.1" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 5 "GAMG: 273.4;RT4: 113.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059570, HPA077233" Approved Supported "Plasma membrane" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane" "HPA059570: AB_2684066, HPA077233: " "unprognostic (2.04e-1)" "unprognostic (2.56e-3)" "unprognostic (5.20e-2)" "unprognostic (1.27e-1)" "unprognostic (6.86e-2)" "unprognostic (1.84e-2)" "unprognostic (1.70e-2)" "unprognostic (7.97e-2)" "unprognostic (8.17e-2)" "unprognostic (9.99e-2)" "unprognostic (2.69e-1)" "unprognostic (1.42e-1)" "unprognostic (3.02e-2)" "unprognostic (2.31e-1)" "unprognostic (1.52e-1)" "unprognostic (9.09e-2)" "unprognostic (6.93e-2)" 3.4 1.6 70.2 1.0 97.1 15.2 2.0 110.5 53.6 3.6 24.9 1.7 1.3 0.5 0.7 0.4 0.3 10.1 23.7 60.5 96.0 37.9 1.1 4.3 2.3 109.4 131.0 0.3 1.7 0.9 1.0 1.6 114.2 78.3 1.3 0.3 2.3 3.0 3.9 4.1 3.4 0.5 97.7 4.6 1.8 0.2 133.8 7.7 6.4 7.8 2.3 90.9 2.2 104.6 0.0 0.4 0.0 0.1 0.0 0.2 0.7 0.4 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 273.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.2 0.1 0.2 0.0 0.0 0.0 0.0 38.3 0.0 0.2 0.0 0.2 0.3 0.1 0.9 0.3 0.0 0.3 0.2 0.0 0.0 0.2 3.0 113.8 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.0 1.8 0.5 0.9 0.1 4.1 0.2 0.1 2.7 1.3 1.3 0.0 0.0 1.1 0.8 0.0 0.0 0.3 0.9 0.9 0.0 0.3 0.2 1.5 0.0 0.9 0.0 0.1 4.1 0.6 70.2 97.1 110.5 53.6 60.5 96.0 109.4 131.0 114.2 97.7 133.8 104.6 136.6 0.0 0.6 228.5 3.1 0.3 313.4 0.1 0.6 0.3 5.4 1.5 10.9 5.7 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.2 0.6 0.0 0.1 28.7 0.0 102.5 0.6 0.2 0.1 3.8 0.0 0.1 0.0 0.2 21.4 0.3 0.1 0.0 0.7 0.2 18.3 0.6 0.3 0.4 0.0 2.0 12.4 5.6 0.1 0.0 5.2 3.5 0.7 0.3 0.0 1.2 2.1 192.6 0.0 0.0 0.0 0.2 0.0 1.7 3.7 0.1 0.2 0.2 0.4 0.0 6.1 0.1 0.0 249.9 SLC22A31 ENSG00000259803 "Solute carrier family 22 member 31" A6NKX4 16 89195761-89201651 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 24.5;lung: 40.6;pancreas: 33.0" "Group enriched" "Detected in some" 4 "Alveolar cells type 2: 130.7;Late spermatids: 33.6" "Cancer enhanced" "Detected in many" "lung cancer: 26.2;thyroid cancer: 20.4" "Region enriched" "Detected in many" 10 "cerebellum: 24.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "BEWO: 33.7;Hep G2: 28.7;NB-4: 14.7;RPMI-8226: 17.7;THP-1: 9.3" NA NA "Cluster 25: Pancreas - Digestion" "Cluster 28: BEWO - Transcription regulation" "Cluster 11: Alveolar cells - Smell perception" "unprognostic (2.71e-3)" "unprognostic (2.53e-1)" "unprognostic (5.02e-3)" "unprognostic (6.82e-2)" "unprognostic (8.20e-2)" "unprognostic (1.95e-1)" "unprognostic (3.00e-2)" "unprognostic (1.93e-2)" "unprognostic (2.12e-1)" "unprognostic (2.67e-1)" "unprognostic (8.98e-2)" "unprognostic (1.09e-1)" "unprognostic (8.26e-4)" "unprognostic (2.74e-1)" "unprognostic (2.05e-1)" "unprognostic (2.72e-3)" "unprognostic (1.89e-1)" 0.2 0.8 0.0 0.2 0.4 0.9 0.1 24.5 1.0 1.1 0.0 0.5 0.4 0.2 0.0 0.1 0.9 0.0 0.3 0.0 0.1 0.8 1.2 40.6 0.1 0.5 1.1 3.1 33.0 0.1 0.5 0.0 2.5 0.6 0.0 0.0 0.4 0.1 0.0 1.8 0.6 0.0 0.3 3.6 3.3 5.2 0.3 0.0 0.4 0.0 0.0 0.2 0.5 0.5 0.0 0.1 0.0 1.6 0.0 0.0 33.7 0.1 0.0 0.0 0.0 1.3 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 28.7 3.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.0 0.5 0.0 14.7 0.8 0.3 3.4 0.0 3.7 17.7 0.0 0.0 1.4 1.0 0.0 0.0 0.0 0.1 0.3 9.3 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 24.5 1.0 0.0 0.1 0.5 1.1 2.5 0.3 0.3 0.5 0.0 6.4 130.7 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 19.2 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.2 0.1 1.1 0.0 8.2 0.0 0.4 0.3 0.7 0.0 0.4 0.0 0.0 0.3 0.0 33.6 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.0 0.2 0.0 0.0 2.2 0.0 0.0 0.0 0.2 0.9 3.2 0.0 0.1 0.0 0.4 0.0 0.0 0.0 SLC22A9 "FLJ23666, OAT4, OAT7, UST3" ENSG00000149742 "Solute carrier family 22 member 9" Q8IVM8 11 63369785-63410294 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 25 "liver: 46.3" "Cell type enhanced" "Detected in some" "Erythroid cells: 2.7;Excitatory neurons: 5.0;granulocytes: 4.5;Hepatocytes: 15.4" "Cancer enriched" "Detected in single" 166 "liver cancer: 19.3" "Region enhanced" "Detected in some" "cerebral cortex: 1.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 15: Hepatocytes - Hemostasis" "unprognostic (2.45e-1)" "unprognostic (7.24e-2)" "unprognostic (8.86e-2)" "unprognostic (2.10e-2)" "unprognostic (1.08e-2)" "unprognostic (2.26e-1)" "unprognostic (2.17e-1)" "unprognostic (2.71e-1)" "unprognostic (3.09e-2)" 0.1 0.0 0.5 0.0 0.5 0.2 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 1.4 0.0 0.2 46.3 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.8 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.1 0.5 0.5 0.0 1.8 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.0 2.7 5.0 0.2 0.0 0.1 0.0 0.0 4.5 0.1 0.0 15.4 0.0 0.0 0.3 0.0 0.0 0.6 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.1 SLC24A5 "JSX, OCA6" ENSG00000188467 "Solute carrier family 24 member 5" Q71RS6 15 48120990-48142672 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Calcium transport, Ion transport, Potassium transport, Sensory transduction, Sodium transport, Symport, Transport" Albinism "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "skin 1: 8.2" "Group enriched" "Detected in some" 7 "Early spermatids: 20.7;Melanocytes: 76.5" "Cancer enriched" "Detected in single" 162 "melanoma: 8.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 800 "SK-MEL-30: 251.8" "Group enriched" "Detected in some" 5 "hippocampal formation: 3.0;pons and medulla: 4.1;thalamus: 1.5" "Low region specificity" "Detected in all" NA NA "Cluster 61: Skin - Cornification" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 29: Early spermatids - Spermatogenesis" "unprognostic (3.47e-2)" "unprognostic (1.80e-1)" "unprognostic (1.35e-1)" "unprognostic (1.92e-3)" 0.0 0.0 0.3 0.0 0.3 0.0 0.2 0.3 0.2 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.0 0.1 0.0 0.1 0.9 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.1 1.7 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 251.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.3 0.2 0.1 0.5 0.1 0.9 0.2 0.0 0.9 0.2 0.3 0.0 0.5 0.7 0.2 2.4 0.0 0.0 0.0 6.4 0.0 0.1 0.3 0.0 0.0 0.0 2.1 0.0 0.1 0.0 0.0 0.0 20.7 1.5 0.1 0.1 0.0 0.4 2.9 0.0 0.0 0.5 0.0 0.9 0.0 0.1 0.0 0.0 0.1 5.0 2.7 0.0 0.0 0.0 0.7 6.6 0.0 0.0 76.5 1.0 0.0 0.9 0.0 1.5 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 4.6 0.0 0.1 0.1 0.1 0.1 0.0 1.0 0.0 0.1 0.0 0.0 0.0 SLC26A3 "CLD, DRA" ENSG00000091138 "Solute carrier family 26 member 3" P40879 7 107765467-107803225 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Transport" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "intestine: 1120.4" "Cell type enriched" "Detected in some" 4 "Distal enterocytes: 2328.4" "Cancer enriched" "Detected in many" 14 "colorectal cancer: 52.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "RPMI-8226: 2.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA036055 Approved NA NA "Cluster 37: Intestine - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA036055: AB_10602401" "unprognostic (1.26e-2)" "unprognostic (1.28e-1)" "unprognostic (1.12e-2)" "unprognostic (2.69e-1)" "unprognostic (4.02e-1)" "unprognostic (4.09e-2)" "unprognostic (3.05e-3)" "unprognostic (6.31e-2)" "unprognostic (1.68e-2)" "unprognostic (1.20e-1)" "unprognostic (1.14e-1)" "unprognostic (2.05e-2)" "unprognostic (8.85e-2)" "unprognostic (8.01e-2)" "unprognostic (5.52e-2)" "unprognostic (2.54e-2)" "unprognostic (3.58e-3)" 1.1 0.0 0.0 19.7 0.0 0.0 59.5 0.2 0.1 0.3 0.0 1120.4 576.9 0.9 15.3 0.5 0.8 17.8 0.0 0.0 0.0 0.8 0.5 0.0 0.2 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 1.1 878.8 0.1 0.0 129.9 0.0 0.1 118.5 15.0 0.0 0.0 1.3 0.9 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 165.9 4.2 0.0 0.3 0.0 0.0 0.0 51.4 41.7 0.3 34.3 0.0 0.0 0.0 0.0 0.0 2328.4 0.0 0.0 6.4 1.8 0.1 0.3 14.3 0.0 110.2 0.0 0.0 0.1 0.0 0.2 26.7 0.2 0.0 0.1 0.0 0.0 114.3 32.5 0.0 0.0 0.0 0.6 0.3 0.1 0.0 89.9 0.0 0.0 0.0 101.6 182.1 0.0 503.4 0.0 0.0 0.3 388.9 0.1 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 2.2 0.0 86.0 0.1 SLC2A14 "GLUT14, SLC2A3P3" ENSG00000173262 "Solute carrier family 2 member 14" Q8TDB8 12 7812512-7891148 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Differentiation, Spermatogenesis, Sugar transport, Transport" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "testis: 81.3" "Cell type enriched" "Detected in many" 5 "Spermatocytes: 65.7" "Cancer enriched" "Detected in single" 35 "testis cancer: 7.1" "Region enhanced" "Detected in many" "cerebellum: 4.7" "Immune cell enhanced" "Detected in some" "basophil: 3.7;neutrophil: 3.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BEWO: 18.4;CACO-2: 31.0;SuSa: 35.5" HPA006539 Supported Approved "Plasma membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 74: Testis - Spermatogenesis" "Cluster 39: CACO-2 - Unknown function" "Cluster 66: Spermatocytes - Spermatogenesis" "Plasma membrane" "HPA006539: AB_1078984" "unprognostic (2.52e-1)" "unprognostic (4.74e-3)" "unprognostic (1.79e-1)" "unprognostic (1.29e-1)" "unprognostic (3.35e-2)" "unprognostic (1.82e-3)" "unprognostic (8.62e-2)" "unprognostic (7.15e-2)" "unprognostic (1.89e-1)" "unprognostic (9.91e-3)" "unprognostic (1.23e-1)" "unprognostic (1.27e-1)" "unprognostic (8.46e-4)" "unprognostic (3.92e-2)" "unprognostic (3.41e-1)" "unprognostic (3.26e-2)" "unprognostic (1.22e-2)" 0.8 5.7 0.7 0.3 0.9 6.2 0.9 4.7 1.0 0.2 1.8 0.9 0.2 0.2 0.2 1.5 0.4 0.9 0.7 1.5 0.9 0.6 3.0 0.5 0.5 0.2 0.1 2.7 6.6 0.0 0.4 1.1 0.5 1.2 0.5 1.4 0.1 0.1 0.5 0.7 0.5 0.5 0.0 0.3 0.2 81.3 1.3 0.2 0.2 0.1 0.2 1.0 0.3 0.5 0.4 1.5 0.7 0.4 0.3 0.8 18.4 0.2 0.0 0.0 0.5 31.0 0.2 0.1 0.8 0.0 0.3 0.2 0.1 0.0 0.0 0.7 0.2 3.3 1.2 8.1 0.1 2.0 4.5 0.0 0.2 0.2 0.0 0.1 0.0 1.1 3.6 0.8 0.0 0.7 0.4 1.6 3.6 0.1 0.0 0.2 0.1 1.1 0.0 0.5 0.6 0.2 0.5 0.7 0.1 35.5 0.1 2.7 0.5 0.1 3.0 0.5 0.5 3.0 1.3 0.6 0.9 0.1 0.6 3.7 0.4 1.0 0.6 0.1 0.6 0.3 0.5 0.4 0.2 0.3 0.3 0.4 3.4 0.6 0.1 0.2 1.0 0.2 0.7 0.9 4.7 1.0 1.5 0.9 0.2 0.1 0.5 0.0 1.3 0.5 2.1 0.0 1.1 0.0 0.9 0.6 0.0 0.0 0.0 0.1 0.1 0.3 2.4 0.0 0.0 0.0 4.2 0.4 0.5 0.1 0.0 0.0 8.9 0.1 1.3 3.2 0.0 6.9 1.9 1.5 1.5 1.9 0.0 0.2 9.5 6.4 5.3 0.5 0.2 0.0 2.2 0.0 0.0 2.5 12.2 5.4 0.3 1.4 1.8 1.9 0.0 0.1 0.0 0.5 0.4 0.3 5.7 2.6 0.1 0.0 0.1 0.0 0.0 0.5 0.0 0.2 2.7 65.7 3.1 0.0 0.1 0.4 3.6 4.2 0.1 0.0 SLC30A10 "DKFZp547M236, ZnT-10, ZNT8, ZRC1" ENSG00000196660 "Solute carrier family 30 member 10" Q6XR72 1 219685427-219958647 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Disease variant, Dystonia, Neurodegeneration, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 23.9;liver: 33.5" "Cell type enhanced" "Detected in some" "Astrocytes: 20.2;Distal enterocytes: 44.3;Early spermatids: 38.3;Hepatocytes: 21.1;Late spermatids: 36.1;Paneth cells: 14.4;Proximal enterocytes: 13.6" "Cancer enriched" "Detected in some" 14 "liver cancer: 7.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 2.0;HEL: 1.5;K-562: 1.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA064547 Enhanced NA NA "Cluster 42: Non-specific - Transcription" "Cluster 45: Intestine - Brush border" "Cluster 1: K-562 - Erythropoiesis" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA064547: AB_2732715" "unprognostic (7.88e-2)" "unprognostic (1.07e-2)" "unprognostic (1.02e-1)" "unprognostic (7.25e-2)" "unprognostic (1.75e-2)" "unprognostic (3.74e-3)" "unprognostic (6.96e-2)" "unprognostic (3.72e-2)" "unprognostic (1.41e-1)" "unprognostic (1.95e-2)" "unprognostic (5.10e-2)" "unprognostic (3.10e-3)" "unprognostic (4.47e-7)" "unprognostic (3.16e-1)" "unprognostic (6.11e-2)" "unprognostic (6.19e-3)" "unprognostic (5.72e-2)" 0.0 0.0 6.0 0.0 6.1 0.3 0.0 4.4 7.6 0.0 7.4 3.8 23.9 0.0 0.0 0.0 0.0 0.4 0.0 5.9 5.7 0.0 33.5 0.0 0.0 5.4 5.9 0.2 0.0 0.0 0.0 0.0 5.6 0.1 5.0 0.4 0.0 0.0 0.7 0.1 8.9 0.0 4.5 0.0 0.0 0.7 6.5 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 1.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.5 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.2 0.1 0.2 0.2 0.2 0.1 0.1 0.1 0.2 0.2 0.2 0.3 0.3 0.3 0.2 0.1 0.1 6.0 6.1 4.4 7.6 5.9 5.7 5.4 5.9 5.6 4.5 6.5 4.7 0.0 0.0 0.0 20.2 0.2 0.3 0.0 0.2 0.0 0.3 0.2 0.0 1.2 1.5 0.1 0.0 0.0 0.1 0.0 44.3 0.0 0.2 38.3 0.0 0.0 1.0 0.0 2.7 4.3 0.0 0.3 0.1 0.0 0.0 0.0 0.5 0.4 21.1 0.1 0.0 4.3 0.6 0.0 0.6 0.3 36.1 1.2 0.0 1.8 9.4 0.0 3.1 0.0 3.0 3.3 0.0 14.4 1.5 0.0 0.0 13.6 0.0 0.0 0.1 0.0 0.0 0.1 1.8 0.9 0.0 0.1 0.3 0.0 1.3 0.8 0.0 SLC35F2 FLJ13018 ENSG00000110660 "Solute carrier family 35 member F2" Q8IXU6 11 107790991-107928293 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 37.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 46.0;Basal prostatic cells: 34.5;Suprabasal keratinocytes: 50.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "PC-3: 188.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA048185, HPA060150" Enhanced Approved "Golgi apparatus" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 37: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Golgi apparatus" "HPA048185: AB_2680304, HPA060150: " "unprognostic (7.73e-2)" "unprognostic (3.28e-3)" "unprognostic (8.37e-3)" "unprognostic (5.77e-2)" "unprognostic (1.38e-3)" "unprognostic (3.07e-2)" "unprognostic (7.26e-2)" "prognostic unfavorable (4.03e-4)" "unprognostic (6.22e-2)" "unprognostic (8.20e-2)" "prognostic unfavorable (5.92e-6)" "unprognostic (1.24e-1)" "unprognostic (4.10e-2)" "unprognostic (1.34e-1)" "unprognostic (7.33e-2)" "unprognostic (3.25e-2)" "unprognostic (1.19e-1)" 4.1 1.2 3.3 7.2 3.9 5.1 5.5 2.3 3.6 16.3 3.2 17.9 19.0 6.3 11.6 12.2 13.5 5.1 3.5 3.8 4.2 10.0 0.5 5.7 7.9 3.5 3.4 5.0 5.4 6.0 3.4 3.2 3.3 22.3 20.4 12.7 37.4 6.1 1.1 20.5 17.8 4.6 4.3 4.0 7.0 4.5 3.5 5.5 7.2 1.5 13.9 7.9 9.5 3.6 30.8 19.8 2.3 30.1 15.2 22.6 29.0 6.8 3.9 17.3 22.7 84.2 31.4 51.2 67.7 20.1 94.1 63.1 37.3 60.5 34.2 40.3 34.8 28.5 18.1 34.1 24.8 65.0 14.2 15.7 36.9 58.3 123.1 53.2 91.7 38.3 74.0 20.7 13.0 17.0 28.3 69.7 20.5 67.5 188.4 57.7 23.9 68.9 100.1 26.7 46.6 20.1 21.9 54.8 14.8 24.7 38.1 15.2 68.0 33.4 53.9 0.8 73.5 54.6 62.5 53.9 21.4 22.0 22.4 0.3 0.2 0.0 3.1 0.1 8.2 10.6 5.3 5.4 6.9 6.5 1.9 2.7 0.6 3.7 0.0 0.3 13.5 1.8 3.3 3.9 2.3 3.6 3.8 4.2 3.5 3.4 3.3 4.3 3.5 3.6 2.7 9.6 1.5 2.0 10.3 46.0 34.5 6.4 14.8 1.1 3.7 2.3 0.6 7.2 9.6 3.7 12.5 0.9 2.5 21.5 3.9 9.5 0.3 13.6 2.8 13.7 6.0 1.7 3.9 8.2 19.1 8.3 6.1 22.9 2.5 5.0 0.7 0.0 4.8 0.0 4.4 10.1 4.1 0.3 15.0 1.0 0.9 3.6 23.2 6.5 3.7 1.2 1.0 4.0 0.4 25.9 10.0 2.6 23.6 20.6 15.1 6.4 0.1 8.0 6.6 2.8 3.1 0.3 7.5 8.6 50.3 4.5 5.7 4.9 24.7 16.6 SLC37A2 FLJ00171 ENSG00000134955 "Solute carrier family 37 member 2" Q8TED4 11 125063302-125090516 "Predicted membrane proteins, Transporters" "Antiport, Sugar transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 78.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 13.4;Hofbauer cells: 36.5;Kupffer cells: 22.0;Macrophages: 22.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "classical monocyte: 12.3;intermediate monocyte: 14.1;myeloid DC: 5.5;non-classical monocyte: 19.2" "Group enriched" "Detected in many" 9 "dendritic cells: 5.5;monocytes: 19.2" "Cell line enhanced" "Detected in many" "A-431: 33.8;CAPAN-2: 70.3;hTCEpi: 34.9;hTERT-HME1: 64.8;U-138 MG: 47.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014948 Uncertain NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 4: Macrophages - Innate immune response" "HPA014948: AB_2190374" "unprognostic (8.47e-2)" "unprognostic (4.85e-1)" "unprognostic (9.64e-2)" "unprognostic (2.91e-2)" "unprognostic (7.88e-2)" "unprognostic (2.84e-1)" "unprognostic (5.47e-2)" "unprognostic (1.68e-1)" "unprognostic (2.06e-2)" "unprognostic (1.30e-1)" "unprognostic (2.15e-2)" "unprognostic (3.11e-1)" "unprognostic (6.61e-2)" "unprognostic (1.94e-3)" "unprognostic (1.66e-3)" "unprognostic (7.01e-2)" "unprognostic (3.24e-2)" 4.2 24.2 1.7 16.9 2.6 1.4 4.6 2.4 3.7 2.3 2.1 8.0 9.1 1.0 1.3 13.4 1.2 5.1 1.5 1.9 2.3 0.7 5.9 5.9 5.7 4.3 2.7 1.0 1.2 1.1 0.2 7.4 3.8 2.6 10.2 0.5 78.8 1.4 0.6 20.9 7.7 3.1 3.2 15.8 2.1 1.6 5.2 2.1 0.6 0.9 5.1 11.9 7.7 7.3 33.8 0.1 1.0 0.4 0.6 0.8 0.6 1.6 2.8 1.0 2.5 0.2 70.3 0.4 9.4 0.4 2.5 21.0 0.4 20.9 3.8 0.9 0.6 6.6 1.6 2.4 0.1 0.3 0.9 0.7 34.9 2.6 64.8 2.7 1.7 1.3 0.5 2.2 3.1 0.3 0.3 4.6 1.9 0.2 1.0 0.4 2.7 0.8 1.0 17.6 0.3 0.3 4.8 2.9 2.6 0.5 0.3 1.8 3.7 47.2 1.9 0.7 1.6 1.8 1.5 1.1 1.7 2.4 4.1 0.2 12.3 0.0 0.0 14.1 0.0 0.4 0.0 0.1 5.5 0.1 0.1 0.1 1.3 0.0 19.2 0.2 0.0 5.4 1.7 2.6 2.4 3.7 1.9 2.3 4.3 2.7 3.8 3.2 5.2 7.3 0.7 0.0 0.6 0.3 3.8 0.3 1.4 0.5 1.2 1.5 1.4 1.1 1.1 1.5 1.6 0.0 2.1 0.6 0.7 13.4 0.0 0.1 1.6 1.9 1.4 1.3 0.0 2.7 0.3 0.0 0.8 0.5 0.0 4.9 2.5 0.4 1.8 0.3 36.5 0.0 0.3 0.1 0.0 22.0 1.4 2.2 0.9 22.7 0.0 8.4 7.3 0.3 3.1 1.0 0.2 0.1 3.3 1.2 1.7 1.0 0.0 0.1 0.2 0.8 0.0 0.8 0.6 2.7 1.1 5.7 0.9 3.4 1.2 0.4 0.1 3.2 SLC39A2 ZIP2 ENSG00000165794 "Solute carrier family 39 member 2" Q9NP94 14 20999255-21001871 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 18.8;seminal vesicle: 33.2;skin 1: 37.5" "Cell type enhanced" "Detected in some" "Muller glia cells: 22.3;Squamous epithelial cells: 12.0;Suprabasal keratinocytes: 6.0;Urothelial cells: 4.4" "Group enriched" "Detected in many" 4 "cervical cancer: 5.1;colorectal cancer: 3.3;head and neck cancer: 6.1;melanoma: 1.9;urothelial cancer: 6.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 71 "HaCaT: 23.2" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA030489, HPA073231" Uncertain Approved "Plasma membrane,Cytoplasmic bodies" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 5: Muller glia cells - Visual perception" "Plasma membrane" "Cytoplasmic bodies" "HPA030489: AB_10601488, HPA073231: " "unprognostic (2.76e-2)" "unprognostic (4.86e-2)" "unprognostic (9.72e-2)" "unprognostic (2.37e-1)" "unprognostic (2.46e-1)" "unprognostic (2.71e-1)" "unprognostic (3.42e-1)" "unprognostic (1.70e-1)" "unprognostic (4.43e-1)" "unprognostic (6.20e-3)" "unprognostic (3.31e-1)" "unprognostic (2.80e-1)" "unprognostic (3.62e-2)" "unprognostic (1.91e-1)" "unprognostic (5.80e-2)" "unprognostic (3.71e-1)" "unprognostic (2.30e-3)" 0.1 0.0 0.2 0.1 0.2 0.0 1.9 0.3 0.3 8.0 0.2 1.9 0.0 0.3 0.1 18.8 0.5 0.4 0.2 0.2 0.2 0.0 0.1 0.1 0.0 0.2 0.3 0.0 0.0 2.3 0.1 0.3 0.2 12.2 1.3 3.7 4.1 33.2 0.2 37.5 0.1 0.2 0.3 0.0 0.0 0.1 0.3 2.8 0.0 0.0 2.7 0.3 14.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 23.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.3 0.2 0.0 0.2 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.3 0.3 0.2 0.2 0.2 0.3 0.2 0.3 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.8 1.1 0.9 0.0 0.2 0.8 0.3 0.4 0.0 0.7 0.0 2.1 0.1 0.0 0.5 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 22.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 2.8 0.2 0.0 0.0 0.9 0.0 0.0 0.2 0.0 0.0 12.0 6.0 0.3 0.0 0.0 1.4 4.4 SLC45A2 "AIM-1, MATP, OCA4" ENSG00000164175 "Solute carrier family 45 member 2" Q9UMX9 5 33944623-33984693 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Melanin biosynthesis, Sensory transduction, Vision" "Albinism, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "liver: 1.2;skin 1: 1.0;testis: 1.0" "Cell type enhanced" "Detected in some" "Early spermatids: 3.1;Excitatory neurons: 4.1;Inhibitory neurons: 5.4;Late spermatids: 5.1;Melanocytes: 12.4;Oligodendrocyte precursor cells: 2.5;Oligodendrocytes: 4.7" "Cancer enriched" "Detected in some" 18 "melanoma: 47.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 28 "SK-MEL-30: 60.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (2.97e-1)" "unprognostic (3.99e-2)" "unprognostic (3.55e-1)" "unprognostic (2.39e-2)" "unprognostic (2.36e-2)" "unprognostic (1.09e-1)" "unprognostic (8.45e-2)" "unprognostic (5.34e-3)" "unprognostic (4.06e-2)" "unprognostic (8.45e-2)" "unprognostic (7.39e-4)" "unprognostic (1.40e-2)" "unprognostic (1.84e-3)" "unprognostic (1.55e-1)" "unprognostic (1.50e-3)" "unprognostic (2.48e-2)" "unprognostic (3.39e-1)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.4 1.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.2 0.4 0.0 0.0 0.1 1.0 0.0 0.0 0.1 0.0 0.2 1.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.0 0.0 60.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.7 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.0 0.3 0.1 0.1 0.2 0.1 0.2 0.4 0.1 0.0 0.0 1.0 0.0 0.6 0.1 0.0 0.0 0.6 0.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 3.1 0.3 0.1 0.3 0.0 0.0 4.1 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.4 5.1 0.0 0.0 12.4 0.0 0.0 0.1 0.0 2.5 4.7 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.1 0.1 0.0 0.3 0.0 0.4 0.0 0.0 0.1 0.1 0.0 SLC46A2 "Ly110, TSCOT" ENSG00000119457 "Solute carrier family 46 member 2" Q9BY10 9 112878920-112890876 "Predicted membrane proteins, Transporters" Transport "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "cervix: 16.5;lung: 10.4;lymphoid tissue: 16.0;skin 1: 24.1" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 39.8;Endometrial ciliated cells: 15.8;Glandular and luminal cells: 6.9;Kupffer cells: 11.8;monocytes: 12.4" "Cancer enhanced" "Detected in some" "lung cancer: 1.4" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "classical monocyte: 24.6;intermediate monocyte: 12.1" "Lineage enriched" "Detected in many" 5 "monocytes: 24.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA020098 Approved NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 31: Skin - Epidermis development" "Cluster 11: Alveolar cells - Smell perception" "HPA020098: AB_2670363" "unprognostic (1.26e-1)" "unprognostic (5.15e-3)" "unprognostic (1.10e-2)" "unprognostic (1.53e-3)" "unprognostic (3.57e-3)" "unprognostic (2.10e-2)" "unprognostic (4.56e-1)" "unprognostic (2.18e-1)" "unprognostic (8.10e-2)" "unprognostic (1.50e-3)" "unprognostic (3.50e-1)" "unprognostic (1.38e-1)" "unprognostic (1.77e-2)" "unprognostic (2.37e-1)" "unprognostic (2.71e-2)" "unprognostic (1.83e-1)" "unprognostic (7.82e-2)" 0.1 0.0 0.1 0.6 0.1 0.1 0.9 0.5 0.2 16.5 0.0 0.0 0.0 3.0 4.7 1.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 10.4 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.2 1.5 0.0 24.1 0.0 0.4 0.0 0.9 0.0 0.6 0.5 16.0 0.0 0.0 0.1 3.0 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.6 0.0 0.1 12.1 0.1 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.3 0.0 10.1 0.2 0.0 6.6 0.1 0.1 0.5 0.2 0.1 0.1 0.1 0.1 0.2 0.0 0.5 0.3 0.0 0.0 39.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.7 1.5 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 15.8 0.8 0.3 0.0 0.0 0.9 0.0 0.0 0.2 0.0 6.9 0.0 0.0 0.4 0.1 2.1 0.0 0.4 0.0 0.0 11.8 1.8 4.4 0.0 4.1 0.0 0.0 12.4 0.0 1.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 SLC6A9 GLYT1 ENSG00000196517 "Solute carrier family 6 member 9" P48067 1 43991500-44031467 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Neurotransmitter transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 72.4;skin 1: 46.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 30.7;Distal enterocytes: 17.8;Erythroid cells: 33.1;Ionocytes: 20.3" "Cancer enhanced" "Detected in all" "glioma: 18.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 62.3;hTCEpi: 106.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013977 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" Nucleoplasm "HPA013977: AB_1849835" "unprognostic (2.73e-2)" "unprognostic (1.92e-2)" "unprognostic (1.63e-1)" "prognostic unfavorable (9.50e-4)" "unprognostic (5.98e-2)" "unprognostic (6.83e-3)" "unprognostic (3.06e-2)" "unprognostic (9.72e-2)" "unprognostic (1.85e-2)" "unprognostic (3.52e-2)" "unprognostic (1.41e-1)" "unprognostic (5.72e-2)" "prognostic unfavorable (5.93e-4)" "unprognostic (5.36e-3)" "unprognostic (1.59e-1)" "unprognostic (2.53e-1)" "unprognostic (1.20e-2)" 3.9 31.0 21.7 4.9 45.5 10.8 4.6 53.2 24.2 12.1 6.3 11.0 2.3 7.4 1.1 23.1 9.5 4.8 2.1 16.1 31.3 4.3 2.3 11.6 1.1 66.3 43.5 2.9 8.2 2.8 1.7 1.4 63.6 3.9 6.3 17.2 11.5 5.5 1.1 46.6 6.0 9.1 45.6 1.9 7.4 1.1 45.9 1.4 5.3 0.6 4.3 12.3 25.1 72.4 19.7 13.7 7.1 18.0 11.2 3.7 15.6 14.7 41.0 24.3 30.1 4.8 7.5 0.3 1.6 42.9 0.0 62.3 11.0 12.5 5.0 0.1 1.8 17.1 33.9 5.8 50.3 3.8 0.7 11.3 106.6 11.9 28.5 15.3 0.6 12.3 13.0 48.5 1.0 10.4 2.9 0.1 5.4 7.4 19.1 2.2 0.0 22.9 2.3 2.2 4.4 4.2 7.4 35.3 7.0 1.7 9.1 10.3 0.2 2.8 11.0 2.4 8.0 53.1 39.2 4.4 9.2 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.7 45.5 53.2 24.2 16.1 31.3 66.3 43.5 63.6 45.6 45.9 72.4 1.5 0.0 2.0 5.9 1.1 7.5 0.9 3.2 8.0 30.7 2.2 0.9 0.7 4.3 2.2 1.8 16.7 0.5 0.5 17.8 0.0 3.7 5.9 4.8 0.4 0.7 0.0 33.1 2.2 8.9 1.0 0.9 1.5 2.7 0.0 0.0 0.0 0.3 0.3 1.7 1.5 2.7 20.3 0.0 1.0 0.8 1.5 0.1 3.6 0.0 1.0 1.2 0.0 3.0 16.4 4.2 3.0 1.5 1.3 2.0 9.1 1.1 12.5 11.1 6.6 0.1 10.0 0.1 0.4 8.9 12.9 0.5 0.3 1.2 2.6 3.2 SMC4 "CAP-C, hCAP-C, SMC4L1" ENSG00000113810 "Structural maintenance of chromosomes 4" Q9NTJ3 3 160399274-160434954 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA condensation, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 60.6" "Cell type enhanced" "Detected in many" "Erythroid cells: 305.8;Spermatocytes: 339.8;Spermatogonia: 239.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "basophil: 74.4" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029449, CAB055509" Approved Supported "Nuclear speckles,Cytosol" NA Yes 25000 "Cluster 18: Basophils - Vesicular transport" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear speckles, Cytosol" "CAB055509: , HPA029449: AB_10603891" "unprognostic (2.63e-1)" "unprognostic (1.01e-1)" "unprognostic (2.45e-2)" "prognostic unfavorable (7.63e-4)" "unprognostic (2.22e-1)" "unprognostic (1.28e-2)" "prognostic unfavorable (2.94e-4)" "unprognostic (9.54e-2)" "unprognostic (2.18e-2)" "unprognostic (5.47e-2)" "prognostic unfavorable (4.20e-5)" "prognostic unfavorable (9.00e-4)" "prognostic unfavorable (8.05e-7)" "unprognostic (3.03e-2)" "unprognostic (4.46e-1)" "unprognostic (1.06e-1)" "unprognostic (4.98e-2)" 6.8 6.5 1.0 21.2 2.0 36.3 6.8 1.2 1.7 6.3 1.5 13.2 14.0 7.4 2.3 23.5 4.5 7.6 7.3 0.9 1.9 5.9 7.8 11.8 37.1 1.7 1.4 5.9 7.8 3.8 2.0 16.2 1.6 5.8 14.9 7.7 4.6 5.0 3.6 11.0 15.4 10.1 1.3 14.7 11.8 32.5 1.9 60.6 9.0 6.8 31.6 9.6 4.3 3.2 386.3 72.8 155.0 73.0 31.5 30.9 72.1 181.2 88.8 206.0 176.8 94.4 209.7 236.6 101.9 81.1 140.0 212.5 183.0 95.0 332.4 297.9 113.8 234.7 123.3 33.6 17.3 158.3 182.6 14.6 13.3 114.4 96.5 78.5 94.8 103.2 130.3 272.2 133.9 78.3 183.2 44.4 91.8 106.7 149.3 180.1 238.8 177.3 43.4 54.8 93.7 94.0 141.4 135.1 65.5 76.6 156.9 128.6 84.8 132.2 105.2 119.9 349.8 181.1 192.2 412.0 96.7 166.9 151.9 74.4 6.0 23.6 11.5 8.9 11.4 17.2 18.2 14.3 6.6 15.0 11.4 10.2 10.8 15.3 15.9 11.7 30.3 9.5 1.0 2.0 1.2 1.7 0.9 1.9 1.7 1.4 1.6 1.3 1.9 3.2 24.6 105.8 174.0 3.9 43.7 40.8 18.2 33.1 30.7 14.9 21.5 21.0 41.3 25.8 35.0 35.0 8.4 74.6 54.4 41.4 3.9 20.9 48.6 35.2 27.0 44.8 30.1 305.8 3.5 14.7 138.1 50.7 32.6 36.1 79.1 77.3 38.2 20.4 61.3 0.0 2.9 44.5 24.4 29.7 43.5 28.3 25.1 36.4 17.8 17.8 39.3 9.3 46.4 3.5 30.1 13.5 26.5 48.2 95.9 14.1 25.9 8.6 25.4 25.8 131.5 21.7 73.2 339.8 239.4 58.1 35.7 34.1 58.4 34.6 69.7 19.1 SMIM29 "C6orf1, LBH, MGC57858" ENSG00000186577 "Small integral membrane protein 29" Q86T20 6 34246381-34249108 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 175.9" "Cell type enhanced" "Detected in many" "Distal tubular cells: 72.4;Ductal cells: 50.9;Hofbauer cells: 104.0;monocytes: 44.5;Proximal tubular cells: 43.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 412.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA037659, HPA037660" Uncertain NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 17: WM-115 - Nervous system development" "Cluster 7: Non-specific - Mitochondria" "HPA037659: AB_2675591, HPA037660: AB_10671881" "unprognostic (2.63e-1)" "unprognostic (3.21e-2)" "unprognostic (1.13e-2)" "unprognostic (2.35e-2)" "unprognostic (2.10e-1)" "unprognostic (3.23e-1)" "unprognostic (1.93e-3)" "unprognostic (1.36e-2)" "unprognostic (2.62e-1)" "unprognostic (4.12e-2)" "prognostic favorable (7.98e-4)" "unprognostic (9.32e-2)" "prognostic unfavorable (4.38e-4)" "unprognostic (3.83e-2)" "unprognostic (2.41e-1)" "unprognostic (1.16e-2)" "unprognostic (3.66e-1)" 19.4 29.7 133.7 14.4 129.9 14.7 19.5 131.5 175.9 26.5 98.3 24.2 8.4 19.8 34.5 26.9 17.0 17.1 29.8 131.3 135.5 22.5 18.7 27.8 21.3 138.0 136.0 16.4 15.4 18.6 33.4 13.2 142.4 22.8 6.1 16.1 16.2 16.3 24.5 48.8 17.9 12.2 133.5 30.8 16.9 11.7 139.1 14.6 25.7 23.5 15.5 24.0 26.0 128.0 25.1 31.1 6.2 33.3 79.2 62.2 6.7 24.6 58.4 27.4 34.4 7.6 12.3 14.1 19.8 28.6 56.6 15.6 12.7 31.3 8.9 36.0 17.3 10.5 6.1 19.9 45.4 12.0 62.0 33.7 28.4 38.5 37.6 38.4 40.9 11.6 13.5 81.8 64.0 17.9 13.5 24.2 1.9 42.8 21.5 5.5 3.8 25.1 33.1 32.4 26.0 12.1 2.6 23.8 70.9 5.3 14.1 19.1 26.4 62.1 14.4 65.1 21.6 42.9 66.1 4.7 35.4 25.7 82.9 99.1 83.8 412.8 78.7 62.7 52.6 133.3 62.4 69.1 59.7 126.4 41.8 61.8 231.6 57.1 48.3 50.1 90.3 64.0 133.7 129.9 131.5 175.9 131.3 135.5 138.0 136.0 142.4 133.5 139.1 128.0 18.1 9.6 13.6 0.0 5.6 0.0 0.0 0.0 0.0 0.0 28.5 20.8 0.0 0.0 6.8 31.3 0.0 37.8 13.6 0.0 72.4 50.9 0.0 9.9 8.6 15.5 0.0 0.0 0.0 24.0 11.8 8.0 0.0 15.0 12.6 10.8 0.0 0.0 104.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.6 0.0 0.0 44.5 0.0 0.0 0.0 0.0 25.3 0.0 0.0 1.9 0.0 0.0 43.8 10.2 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 35.4 9.4 17.8 0.0 0.0 SMPD3 NSMASE2 ENSG00000103056 "Sphingomyelin phosphodiesterase 3" Q9NY59 16 68358327-68448508 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Lipid metabolism, Sphingolipid metabolism" "Developmental protein, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 61.5;lymphoid tissue: 52.0" "Cell type enhanced" "Detected in many" "dendritic cells: 77.1;Gastric mucus-secreting cells: 70.8;Horizontal cells: 301.2;Proximal enterocytes: 115.1" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "amygdala: 8.0;basal ganglia: 29.7;cerebral cortex: 24.9;hippocampal formation: 25.4" "Immune cell enriched" "Detected in many" 7 "plasmacytoid DC: 138.9" "Lineage enriched" "Detected in many" 7 "dendritic cells: 138.9" "Cell line enhanced" "Detected in some" "HMC-1: 9.7;MOLT-4: 14.7;RPMI-8226: 12.4;SCLC-21H: 13.4" "Region enhanced" "Detected in all" "basal ganglia: 115.2" "Region enhanced" "Detected in all" "basal ganglia: 67.7" "CAB033885, HPA065535, HPA069383" Approved Supported "Endoplasmic reticulum" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 56: Intestine - Transmembrane transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 62: Horizontal cells - Visual perception" "Endoplasmic reticulum" "CAB033885: AB_1126788, HPA065535: , HPA069383: " "unprognostic (1.21e-1)" "prognostic favorable (7.72e-4)" "unprognostic (5.61e-3)" "prognostic favorable (3.86e-4)" "unprognostic (2.46e-1)" "unprognostic (5.85e-4)" "unprognostic (7.87e-2)" "unprognostic (8.12e-3)" "unprognostic (2.77e-2)" "unprognostic (1.30e-1)" "unprognostic (1.75e-1)" "unprognostic (1.81e-1)" "unprognostic (1.04e-3)" "unprognostic (5.02e-3)" "unprognostic (2.49e-1)" "unprognostic (1.19e-1)" "unprognostic (1.93e-3)" 6.8 2.1 8.0 3.6 29.7 1.8 2.8 1.8 24.9 2.7 0.1 13.8 61.5 1.4 0.1 2.1 3.8 9.0 1.5 25.4 0.5 4.0 7.4 2.5 4.2 0.0 0.2 4.8 2.6 0.1 16.5 0.2 0.6 4.6 6.9 6.5 3.0 0.3 2.4 13.6 57.7 0.7 0.5 3.4 23.2 8.6 5.1 52.0 2.7 0.0 1.9 1.7 2.5 2.3 0.3 0.8 0.4 0.1 0.0 0.0 5.5 0.4 0.0 0.4 0.1 3.1 1.0 0.4 0.6 0.3 0.2 1.2 0.0 0.0 0.1 0.3 0.7 0.1 2.7 0.3 0.0 0.0 9.7 0.0 0.0 0.0 0.2 0.5 0.0 0.9 0.9 0.3 0.3 0.2 14.7 2.8 0.6 4.9 0.1 0.7 0.2 12.4 0.0 0.1 13.4 2.7 0.4 1.6 0.7 0.2 1.1 0.9 0.0 0.4 0.8 1.4 0.1 2.3 1.2 0.3 0.2 0.9 0.2 4.4 0.0 20.7 2.3 0.1 0.3 1.7 0.2 0.6 0.1 0.9 0.6 0.3 0.1 0.1 0.0 138.9 1.9 1.2 8.0 29.7 1.8 24.9 25.4 0.5 0.0 0.2 0.6 0.5 5.1 2.3 0.3 3.2 1.1 1.0 2.6 0.1 1.5 0.6 0.0 50.8 1.8 0.6 2.9 15.7 1.5 0.0 0.0 0.0 77.1 44.7 0.0 1.3 8.5 3.0 0.3 0.6 25.8 0.4 33.8 0.9 0.1 5.2 70.8 0.5 0.0 0.2 0.7 9.4 0.3 301.2 20.4 34.7 2.0 1.0 0.5 18.6 15.2 2.9 0.0 1.9 0.6 0.9 1.0 10.6 1.7 1.6 39.9 45.9 2.5 3.6 115.1 0.0 14.6 3.9 0.0 0.2 0.3 10.0 2.1 0.1 1.0 0.0 6.2 0.2 21.6 5.4 SNORC "ASCL830, C2orf82, UNQ830" ENSG00000182600 "Secondary ossification center associated regulator of chondrocyte maturation" Q6UX34 2 232857270-232878708 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 55.0;breast: 14.2;skin 1: 32.2" "Group enriched" "Detected in some" 22 "Breast glandular cells: 367.0;Breast myoepithelial cells: 324.9" "Cancer enhanced" "Detected in many" "liver cancer: 7.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 20 "basophil: 2.8" "Lineage enriched" "Detected in single" 20 "granulocytes: 2.8" "Cell line enriched" "Detected in some" 13 "Hep G2: 59.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA052824 Approved Approved Nucleoplasm,Nucleoli "Intracellular and membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 35: Glandular cells - Unknown function" "Nucleoplasm, Nucleoli" "HPA052824: AB_2681964" "unprognostic (4.58e-3)" "unprognostic (1.31e-1)" "unprognostic (2.47e-2)" "prognostic unfavorable (3.56e-4)" "unprognostic (1.27e-1)" "unprognostic (2.11e-1)" "unprognostic (3.06e-1)" "unprognostic (4.71e-1)" "unprognostic (1.23e-3)" "unprognostic (3.52e-1)" "unprognostic (1.79e-1)" "unprognostic (2.00e-1)" "unprognostic (4.30e-7)" "unprognostic (1.83e-3)" "unprognostic (8.15e-2)" "unprognostic (1.58e-2)" "unprognostic (1.33e-2)" 1.3 0.9 6.7 0.2 14.1 0.5 14.2 21.2 8.5 0.7 0.2 3.3 0.9 0.7 0.5 1.0 1.2 0.0 0.8 11.9 23.5 1.3 7.4 0.8 0.6 37.8 14.8 0.7 1.7 0.3 1.6 0.2 28.3 1.5 0.3 0.6 4.7 0.1 1.0 32.2 1.7 0.1 38.2 1.1 0.8 8.1 14.2 0.1 0.6 0.0 0.0 0.9 0.8 55.0 0.9 0.0 0.3 1.4 1.0 1.6 2.4 0.3 0.0 0.3 0.7 0.0 0.2 0.0 0.7 0.1 0.5 0.5 0.0 0.0 0.0 0.6 2.1 0.5 0.4 59.6 0.8 0.1 1.7 0.0 1.3 0.4 0.8 0.7 1.6 0.6 0.1 0.2 0.2 0.2 0.2 0.5 0.0 0.0 2.2 0.4 0.6 0.4 0.1 0.9 0.2 0.8 0.4 0.0 2.2 1.0 0.1 2.6 0.9 0.2 0.8 0.8 0.8 3.8 4.7 0.2 0.1 1.4 0.4 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 14.1 21.2 8.5 11.9 23.5 37.8 14.8 28.3 38.2 14.2 55.0 3.1 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 367.0 324.9 0.0 0.0 0.0 1.8 0.0 0.1 10.1 0.0 5.9 0.5 0.0 3.8 0.4 6.3 0.0 0.0 0.0 0.8 0.1 2.9 0.0 2.3 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 0.0 0.0 0.0 0.0 0.0 12.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 1.0 2.3 0.9 0.0 0.0 SOX15 "SOX20, SOX26, SOX27" ENSG00000129194 "SRY-box transcription factor 15" O60248 17 7588178-7590094 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 87.4;skin 1: 48.2" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 209.2;Basal squamous epithelial cells: 447.3;Squamous epithelial cells: 388.1;Suprabasal keratinocytes: 169.9" "Cancer enhanced" "Detected in many" "testis cancer: 67.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 6.7;non-classical monocyte: 10.6" "Lineage enriched" "Detected in many" 5 "monocytes: 10.6" "Group enriched" "Detected in many" 8 "A-431: 130.6;HaCaT: 142.1;HBEC3-KT: 57.8;hTCEpi: 56.6" "Not detected" "Not detected" "HPA067196, HPA074049" Enhanced Supported "Nucleoplasm,Nucleoli,Golgi apparatus,Vesicles" Yes NA "Cluster 51: Monocytes - Innate immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "Nucleoli, Golgi apparatus, Vesicles" "HPA067196: AB_2685802, HPA074049: AB_2686656" "unprognostic (5.79e-3)" "unprognostic (6.65e-2)" "unprognostic (1.40e-2)" "unprognostic (2.58e-2)" "unprognostic (2.72e-1)" "unprognostic (1.60e-1)" "unprognostic (6.02e-2)" "unprognostic (2.81e-2)" "unprognostic (5.00e-2)" "unprognostic (8.50e-2)" "unprognostic (1.59e-1)" "unprognostic (1.24e-1)" "unprognostic (8.61e-3)" "unprognostic (1.03e-1)" "unprognostic (1.96e-1)" "unprognostic (2.95e-2)" "unprognostic (2.97e-1)" 2.2 0.9 15.0 0.8 14.6 2.7 3.4 17.4 23.3 21.1 11.8 12.4 0.7 8.2 1.7 87.4 11.0 1.0 8.6 14.5 15.3 1.7 1.3 1.5 0.5 14.3 15.0 15.3 1.0 0.2 7.9 0.3 14.1 12.1 0.5 5.0 14.6 7.1 2.3 48.2 3.5 1.3 14.5 1.1 4.7 2.6 14.7 1.0 2.3 1.8 2.8 10.4 32.7 15.0 130.6 3.2 1.8 1.0 0.1 0.3 9.6 1.4 0.5 1.1 1.7 2.5 0.8 0.4 1.2 0.1 0.4 142.1 0.1 57.8 0.4 3.3 3.9 0.5 1.7 0.5 0.2 0.3 2.6 0.0 56.6 0.7 11.9 3.6 0.0 2.6 2.9 0.8 0.2 0.9 0.6 1.5 3.6 0.3 0.7 1.6 1.8 1.0 2.7 0.7 0.8 2.2 1.5 0.5 0.7 5.5 1.1 1.0 1.6 1.3 2.3 1.6 4.4 0.9 1.5 1.6 4.4 1.7 3.2 0.1 2.1 0.0 0.0 6.7 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 10.6 1.0 0.0 0.4 15.0 14.6 17.4 23.3 14.5 15.3 14.3 15.0 14.1 14.5 14.7 15.0 0.8 0.0 0.0 2.6 0.1 209.2 51.8 72.7 447.3 13.6 6.3 13.0 4.7 0.0 20.6 1.8 14.6 1.7 0.7 0.5 1.9 0.1 0.2 0.4 4.9 3.1 1.2 0.0 8.1 0.5 2.0 10.4 0.0 0.4 0.0 1.3 1.4 0.0 0.4 10.1 7.7 0.4 10.2 1.2 19.3 1.1 31.4 0.9 26.6 1.0 1.2 50.0 0.0 4.0 2.4 0.5 0.1 36.9 4.9 21.2 0.3 0.2 16.2 9.4 32.9 7.8 7.1 0.7 10.9 388.1 169.9 1.1 1.1 0.6 0.8 73.8 SPAG1 "CILD28, CT140, FLJ32920, HSD-3.8, SP75, TPIS" ENSG00000104450 "Sperm associated antigen 1" Q07617 8 100157906-100259278 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Fertilization Hydrolase "Ciliopathy, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 96.0;Endometrial ciliated cells: 190.6;Respiratory ciliated cells: 198.6;Spermatocytes: 91.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "A-431: 31.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023748, HPA053682" Enhanced Supported Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "HPA023748: AB_2671304, HPA053682: AB_2682229" "unprognostic (9.95e-2)" "unprognostic (5.37e-2)" "unprognostic (1.38e-2)" "unprognostic (4.24e-2)" "unprognostic (1.46e-1)" "unprognostic (2.57e-1)" "unprognostic (5.86e-2)" "unprognostic (9.19e-2)" "unprognostic (1.53e-1)" "unprognostic (5.62e-2)" "unprognostic (1.57e-1)" "unprognostic (1.17e-1)" "prognostic unfavorable (3.87e-4)" "unprognostic (9.11e-3)" "unprognostic (8.83e-3)" "unprognostic (1.54e-1)" "prognostic favorable (2.62e-4)" 1.8 1.3 3.0 3.6 3.2 10.1 3.0 4.2 3.0 5.4 14.0 12.9 2.9 2.4 1.5 7.8 10.0 3.7 1.5 3.0 4.6 3.2 4.7 5.0 2.7 7.2 9.0 1.0 2.5 9.0 5.7 1.8 6.2 3.1 18.3 1.9 4.6 3.5 0.4 7.9 2.7 1.8 6.0 2.0 6.3 19.4 4.8 2.1 3.4 0.6 4.4 5.3 3.0 5.4 31.3 8.3 0.5 1.8 1.8 1.5 4.6 5.7 3.4 6.8 7.1 8.3 13.5 1.2 20.0 1.8 10.1 16.1 5.9 11.1 6.3 18.1 6.1 5.2 9.0 3.1 2.4 1.4 4.5 1.3 5.8 8.4 6.6 5.3 5.8 5.7 0.2 16.1 1.0 11.2 3.1 1.4 0.5 15.6 9.1 0.5 1.3 4.7 26.1 14.8 4.8 3.5 7.8 6.4 7.0 2.2 9.2 5.9 5.3 6.8 9.8 3.6 14.9 10.9 8.9 0.9 6.5 5.0 3.4 0.0 0.1 0.6 0.1 0.0 0.0 0.8 0.1 0.1 0.1 0.3 0.0 0.1 0.7 1.0 0.2 0.2 0.0 0.0 3.0 3.2 4.2 3.0 3.0 4.6 7.2 9.0 6.2 6.0 4.8 5.4 7.7 48.1 22.8 18.9 7.7 5.6 9.6 18.1 2.2 2.0 13.3 7.7 5.6 22.8 37.2 18.4 0.0 1.3 19.0 32.9 5.9 19.7 96.0 190.6 7.1 6.9 22.1 0.4 30.1 8.6 8.7 5.0 22.4 39.5 10.1 7.3 4.2 8.0 2.8 8.4 21.6 14.9 6.1 2.2 5.3 32.3 5.0 3.9 1.8 6.5 4.5 11.5 5.2 4.5 4.1 14.9 17.7 3.8 15.9 10.3 2.4 10.0 198.6 2.3 0.0 4.8 6.4 91.9 4.7 2.9 5.4 2.3 12.0 1.3 20.1 23.3 SPAG5 "DEEPEST, hMAP126, MAP126" ENSG00000076382 "Sperm associated antigen 5" Q96R06 17 28577565-28599025 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 37.9;kidney: 37.8;testis: 74.0" "Cell type enhanced" "Detected in many" "Early spermatids: 126.0;Erythroid cells: 37.2;Spermatocytes: 72.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 11.7;T-reg: 4.9" "Group enriched" "Detected in many" 6 "granulocytes: 11.7;T-cells: 4.9" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA022008, HPA022479, HPA024418" Approved Supported "Nuclear bodies,Mitotic spindle,Cytosol" Yes Yes "Cluster 34: Basophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear bodies, Mitotic spindle" Cytosol "HPA022008: AB_1853519, HPA022479: AB_1853521, HPA024418: " "unprognostic (4.71e-2)" "unprognostic (1.32e-1)" "unprognostic (5.31e-3)" "unprognostic (2.32e-3)" "unprognostic (3.50e-1)" "unprognostic (1.55e-1)" "prognostic unfavorable (5.43e-5)" "unprognostic (3.37e-3)" "unprognostic (4.84e-3)" "unprognostic (5.97e-2)" "prognostic unfavorable (3.02e-4)" "unprognostic (3.49e-2)" "prognostic unfavorable (5.43e-13)" "unprognostic (2.64e-1)" "unprognostic (1.66e-1)" "unprognostic (2.90e-2)" "unprognostic (2.01e-1)" 2.2 3.3 7.8 7.8 7.6 37.9 2.4 5.8 9.1 2.6 3.4 8.3 7.9 1.9 2.4 8.3 1.7 1.8 1.4 7.6 7.7 37.8 14.8 3.4 14.5 6.7 6.8 2.7 1.5 1.1 4.3 5.7 6.7 2.2 10.7 10.8 2.4 0.8 1.0 5.5 9.1 3.4 5.0 7.4 3.6 74.0 7.7 22.4 8.7 0.7 17.3 2.6 3.6 7.5 84.7 87.7 103.3 78.4 5.2 8.6 42.4 65.9 42.4 98.1 78.3 69.2 25.5 59.8 34.2 46.8 91.7 70.2 114.5 42.7 103.8 108.6 72.9 62.9 87.9 80.2 0.6 83.1 76.1 2.9 3.8 78.6 40.4 14.5 52.1 90.6 69.7 101.5 80.7 52.6 109.4 92.9 54.2 68.3 44.5 72.1 144.4 70.9 29.0 43.0 78.6 45.8 96.4 114.9 31.6 84.9 82.2 70.6 25.7 56.4 91.3 46.6 114.6 46.7 72.9 87.3 37.8 60.6 91.8 11.7 0.0 0.0 0.4 0.4 0.7 0.6 1.2 0.9 0.1 1.4 1.1 0.9 0.2 0.8 0.3 0.3 4.9 0.9 7.8 7.6 5.8 9.1 7.6 7.7 6.7 6.8 6.7 5.0 7.7 7.5 0.5 3.2 1.7 0.7 3.3 2.0 0.9 1.3 1.2 5.0 1.1 1.0 0.7 0.0 1.9 0.0 0.0 9.0 1.3 4.7 1.9 0.5 126.0 6.0 1.1 1.5 13.1 37.2 5.2 0.4 12.2 2.6 5.1 1.8 1.3 12.6 3.3 6.3 6.5 3.3 6.0 4.6 4.1 2.7 4.0 25.2 0.9 6.1 0.0 1.9 0.9 0.7 0.0 2.0 1.7 0.4 4.7 0.0 13.1 0.8 8.1 12.5 7.7 3.9 6.6 2.0 2.2 72.6 21.0 5.2 1.0 3.8 2.8 0.9 5.1 1.1 SPAG6 "CFAP194, CT141, FAP194, PF16, Repro-SA-1" ENSG00000077327 "Sperm associated antigen 6" O75602 10 22345445-22454224 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 63.5;fallopian tube: 49.0;testis: 96.3" "Cell type enhanced" "Detected in some" "Early spermatids: 228.6;Endometrial ciliated cells: 73.2;Respiratory ciliated cells: 266.4;Spermatocytes: 372.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 29 "U-937: 105.6" "Low region specificity" "Detected in single" "Region enhanced" "Detected in many" "midbrain: 11.1" HPA038440 Enhanced NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 32: U-937 - Innate immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA038440: AB_10671742" "unprognostic (5.02e-2)" "unprognostic (9.52e-2)" "unprognostic (8.94e-6)" "unprognostic (2.21e-1)" "unprognostic (2.51e-2)" "unprognostic (4.91e-3)" "unprognostic (1.68e-1)" "unprognostic (2.38e-1)" "unprognostic (8.68e-2)" "unprognostic (1.07e-2)" "unprognostic (2.52e-1)" "unprognostic (1.26e-1)" "unprognostic (2.71e-1)" "unprognostic (1.06e-3)" "unprognostic (3.10e-2)" "unprognostic (2.78e-4)" 0.0 0.0 4.2 0.0 4.0 0.4 1.7 1.9 1.4 1.7 63.5 0.0 0.0 0.2 0.4 0.0 49.0 0.0 0.1 3.3 5.0 0.3 0.1 7.0 0.1 17.6 16.1 0.1 0.3 1.8 14.6 0.0 9.9 1.0 0.0 5.8 0.0 0.0 0.0 0.3 0.0 0.0 16.3 0.0 0.0 96.3 6.4 0.4 0.1 0.0 0.0 0.0 0.0 10.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.9 2.1 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 3.6 0.0 0.0 0.0 0.3 0.0 2.5 0.0 0.0 0.0 0.0 0.1 1.7 0.8 0.2 0.0 105.6 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.1 0.0 4.2 4.0 1.9 1.4 3.3 5.0 17.6 16.1 9.9 16.3 6.4 10.1 0.0 0.0 4.8 0.0 0.1 0.1 0.1 14.0 0.0 0.2 0.5 0.3 0.6 0.0 24.5 0.0 0.0 0.1 0.2 0.1 1.9 0.3 228.6 73.2 0.4 0.2 0.0 0.0 7.1 0.0 0.0 0.7 0.0 1.0 1.3 0.0 0.0 0.0 0.0 0.0 3.1 0.0 16.2 0.0 0.2 51.4 5.0 0.5 1.8 4.7 0.0 0.3 0.0 0.5 6.0 0.4 0.0 4.9 0.3 1.8 0.0 1.4 266.4 1.2 0.0 0.0 3.7 372.6 4.8 0.0 0.1 0.0 0.5 0.1 0.0 0.1 SPC25 "AD024, MGC22228, SPBC25" ENSG00000152253 "SPC25 component of NDC80 kinetochore complex" Q9HBM1 2 168834132-168913371 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 8.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 23.5;Erythroid cells: 29.9;Extravillous trophoblasts: 37.9;Muller glia cells: 17.2;Spermatocytes: 26.2;Spermatogonia: 20.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA047144, HPA050544" Enhanced Enhanced Cytosol NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 29: U-266 - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA047144: AB_2679952, HPA050544: " "unprognostic (3.52e-2)" "unprognostic (2.28e-2)" "unprognostic (2.23e-1)" "prognostic unfavorable (8.61e-5)" "unprognostic (3.15e-1)" "unprognostic (1.84e-2)" "prognostic unfavorable (4.74e-6)" "prognostic unfavorable (9.44e-5)" "unprognostic (1.84e-3)" "unprognostic (7.58e-2)" "unprognostic (1.36e-1)" "unprognostic (1.30e-2)" "unprognostic (1.11e-16)" "unprognostic (9.91e-3)" "unprognostic (1.85e-1)" "unprognostic (3.43e-1)" "unprognostic (1.57e-1)" 0.6 0.8 0.6 0.7 0.6 4.2 1.0 0.3 1.5 0.7 0.5 2.1 3.7 0.5 0.0 4.4 0.3 0.5 0.4 1.6 0.7 1.1 0.8 0.9 3.9 0.6 0.7 0.5 1.3 0.1 0.1 1.1 0.8 0.4 1.6 1.7 1.0 0.0 0.6 1.1 2.1 1.0 0.1 2.1 1.6 3.4 0.6 8.5 0.2 0.1 3.7 0.5 1.5 1.8 1.0 16.8 40.6 22.8 1.8 1.9 14.5 22.9 9.3 23.5 18.1 5.6 16.2 15.7 9.0 3.4 31.9 20.9 15.9 0.0 20.7 10.0 21.5 30.2 7.2 2.2 0.1 20.3 8.9 0.3 1.0 14.3 0.0 4.7 10.3 28.2 0.8 15.7 6.4 9.8 16.1 26.3 0.9 11.2 21.0 28.8 38.1 5.6 9.6 13.7 30.4 0.5 16.8 14.4 3.9 13.5 0.4 16.4 2.5 3.6 42.1 13.4 18.2 31.4 56.0 12.5 4.1 0.5 14.3 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.2 0.1 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.1 0.6 0.6 0.3 1.5 1.6 0.7 0.6 0.7 0.8 0.1 0.6 1.8 0.4 0.0 1.1 0.7 4.2 5.4 1.5 7.1 1.2 0.0 1.5 2.4 0.6 0.0 2.6 0.0 0.0 23.5 1.5 3.7 0.0 0.2 2.0 0.5 1.8 1.6 0.0 29.9 0.3 0.0 37.9 4.6 2.0 1.8 0.0 10.1 2.9 1.2 15.1 0.0 0.5 5.2 2.0 1.9 2.4 1.6 0.6 2.0 0.0 0.0 0.0 17.2 0.0 5.0 0.2 0.5 0.1 1.2 15.3 1.0 1.0 0.2 0.1 0.6 0.0 1.3 4.4 26.2 20.1 7.3 1.4 5.7 2.7 1.7 9.9 2.5 SPDEF "bA375E1.3, PDEF" ENSG00000124664 "SAM pointed domain containing ETS transcription factor" O95238 6 34537802-34556333 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 140.7;salivary gland: 114.8" "Cell type enhanced" "Detected in many" "Breast glandular cells: 94.2;Breast myoepithelial cells: 61.1;Intestinal goblet cells: 315.1;Prostatic glandular cells: 72.7" "Cancer enhanced" "Detected in many" "prostate cancer: 388.1" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "MCF7: 288.4;OE19: 118.0;SK-BR-3: 192.2;T-47d: 154.0" "Not detected" "Not detected" "Region enriched" "Detected in single" 7 "midbrain: 2.9" HPA055707 Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 27: Mucus-secreting cells - Mucin production" "Nucleoplasm, Nucleoli" Cytosol "HPA055707: AB_2682894" "unprognostic (2.98e-1)" "unprognostic (9.68e-2)" "unprognostic (2.84e-1)" "prognostic favorable (9.26e-9)" "unprognostic (1.57e-1)" "unprognostic (7.10e-3)" "unprognostic (2.56e-2)" "unprognostic (1.15e-1)" "unprognostic (1.63e-1)" "unprognostic (7.39e-3)" "unprognostic (3.48e-3)" "unprognostic (2.92e-1)" "unprognostic (6.16e-11)" "unprognostic (8.04e-2)" "unprognostic (1.85e-1)" "unprognostic (1.47e-1)" "unprognostic (1.12e-2)" 0.4 0.1 0.5 1.4 0.5 0.1 36.6 0.8 1.1 28.0 0.0 18.4 11.6 9.0 0.5 2.2 6.3 2.4 0.4 0.5 0.2 0.1 0.1 1.1 0.0 0.3 0.4 0.1 0.6 0.0 0.2 0.0 0.2 140.7 10.2 0.0 114.8 0.1 0.3 9.3 14.3 0.6 0.1 0.1 35.4 0.3 0.5 0.0 0.1 0.0 0.0 1.0 0.3 0.5 0.0 30.9 0.1 0.2 0.0 0.0 0.5 0.0 0.0 0.1 0.2 0.3 0.3 0.0 0.1 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 288.4 0.3 0.4 0.0 118.0 38.6 0.1 0.0 0.3 0.3 0.3 2.1 0.2 0.0 192.2 0.0 0.0 154.0 0.0 0.0 0.0 0.5 0.4 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.8 1.1 0.5 0.2 0.3 0.4 0.2 0.1 0.5 0.5 0.8 0.0 2.2 0.7 0.3 0.1 13.3 20.7 0.0 0.0 94.2 61.1 0.3 5.7 31.7 0.0 0.0 0.0 1.4 27.1 0.0 2.6 1.1 6.2 0.7 0.6 5.4 0.0 0.8 1.2 0.0 0.4 28.1 18.7 0.0 0.2 0.4 0.0 0.0 0.0 0.6 315.1 12.2 0.0 0.2 5.5 0.0 0.9 3.6 0.0 0.0 0.0 0.0 0.0 0.2 20.2 12.3 0.0 0.1 72.7 5.7 0.0 2.9 0.0 0.0 0.0 1.2 0.1 0.2 0.0 0.0 0.3 0.8 0.0 30.0 11.5 SPPL3 "DKFZP586C1324, IMP2, MGC126674, MGC126676, MGC90402, PSL4" ENSG00000157837 "Signal peptide peptidase like 3" Q8TCT6 12 120762510-120904358 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 192.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004194, HPA059958" Uncertain Supported "Vesicles,Plasma membrane" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" "Vesicles, Plasma membrane" "HPA004194: AB_2667171, HPA059958: AB_2684179" "unprognostic (3.29e-1)" "unprognostic (2.29e-2)" "unprognostic (3.39e-2)" "unprognostic (1.63e-1)" "unprognostic (2.06e-1)" "unprognostic (7.96e-3)" "prognostic unfavorable (1.29e-5)" "unprognostic (3.17e-2)" "unprognostic (1.10e-1)" "unprognostic (1.28e-1)" "unprognostic (2.48e-1)" "unprognostic (2.44e-1)" "unprognostic (2.66e-1)" "unprognostic (9.34e-2)" "unprognostic (9.92e-2)" "unprognostic (7.54e-2)" "unprognostic (9.40e-2)" 20.9 14.9 25.3 11.9 28.1 20.9 24.2 29.0 27.5 30.0 13.1 26.7 18.2 26.3 15.7 44.3 28.6 18.7 18.1 25.4 30.6 22.8 19.3 20.4 15.9 25.0 26.0 31.4 21.3 49.6 13.9 28.4 26.1 20.6 27.2 15.5 20.2 27.0 15.7 56.5 18.8 29.6 24.1 24.3 15.2 39.0 26.4 32.7 31.2 19.6 27.8 28.6 34.2 31.4 30.0 29.2 43.4 27.4 56.2 37.7 30.5 22.5 66.6 47.4 37.9 30.5 29.9 27.4 0.1 39.4 42.0 35.6 44.8 48.4 48.9 21.9 27.5 23.6 16.2 23.4 59.2 27.4 29.3 38.1 75.9 40.7 38.1 56.0 47.1 41.5 26.5 13.4 41.2 26.3 36.7 22.0 29.2 27.8 20.6 21.6 36.6 19.7 36.8 83.8 29.7 31.9 42.8 19.6 34.7 46.1 58.9 18.7 35.4 21.9 29.5 13.6 17.1 30.9 60.3 26.4 32.5 22.3 36.9 4.8 1.2 1.1 1.3 1.2 1.8 1.3 1.6 1.7 2.1 1.6 1.5 1.7 2.2 1.3 1.1 2.7 1.4 0.7 25.3 28.1 29.0 27.5 25.4 30.6 25.0 26.0 26.1 24.1 26.4 31.4 35.2 19.2 20.8 79.3 25.3 55.1 32.3 29.4 43.3 37.8 35.2 24.1 21.2 20.0 19.8 40.5 27.1 42.0 21.2 47.2 1.9 19.3 8.6 20.9 26.9 33.0 27.1 14.5 97.2 24.7 29.0 33.2 25.0 29.7 4.5 68.7 37.5 33.1 38.3 37.0 112.6 33.7 22.4 38.1 39.3 8.0 28.6 34.5 26.6 79.6 26.6 23.0 16.5 141.3 192.3 22.8 34.9 35.0 22.0 33.4 34.0 18.1 18.1 22.4 13.1 32.3 27.4 55.6 41.1 76.9 84.7 64.6 22.4 35.0 35.4 37.6 SPRR5 ENSG00000283227 "Small proline rich protein 5" A0A1B0GTR4 1 152947154-152949258 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 24 "skin 1: 115.2" "Cell type enhanced" "Detected in single" "Exocrine glandular cells: 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "HaCaT: 2.0;hTCEpi: 5.3" NA NA "Cluster 61: Skin - Cornification" "Cluster 30: Epithelial cell lines - Translation" "Cluster 1: Pancreatic cells - Digestion" 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.7 115.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 STAC2 24b2 ENSG00000141750 "SH3 and cysteine rich domain 2" Q6ZMT1 17 39210541-39225945 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 59.5;breast: 56.2;retina: 120.9;skin 1: 53.1" "Cell type enriched" "Detected in many" 9 "Muller glia cells: 496.8" "Cancer enhanced" "Detected in many" "breast cancer: 15.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "GAMG: 9.8;HeLa: 32.5;U-87 MG: 13.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA076925 Approved Cytosol NA NA "Cluster 77: Retina - Visual perception" "Cluster 20: HeLa - Mitochondria" "Cluster 5: Muller glia cells - Visual perception" Cytosol "HPA076925: " "unprognostic (1.70e-3)" "unprognostic (1.05e-1)" "unprognostic (3.09e-2)" "prognostic unfavorable (4.05e-5)" "prognostic unfavorable (5.61e-4)" "unprognostic (1.42e-1)" "unprognostic (8.66e-2)" "unprognostic (2.94e-2)" "unprognostic (1.17e-2)" "prognostic unfavorable (6.66e-4)" "unprognostic (1.12e-2)" "unprognostic (5.16e-2)" "unprognostic (2.35e-3)" "unprognostic (2.05e-2)" "unprognostic (1.94e-1)" "unprognostic (3.54e-2)" "unprognostic (3.17e-1)" 2.2 0.5 11.2 0.2 24.6 0.0 56.2 10.3 59.5 8.5 2.2 0.9 0.1 5.2 10.7 0.5 4.8 0.0 2.5 14.5 22.4 14.2 0.0 0.8 0.0 30.9 18.3 2.4 0.2 0.1 1.6 0.2 30.7 5.1 0.1 120.9 15.1 23.5 0.3 53.1 0.6 0.8 5.4 0.1 0.4 0.2 5.4 0.0 0.1 0.6 0.0 0.5 2.6 34.2 0.0 0.0 0.5 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 9.8 0.0 3.9 0.0 0.0 0.0 0.5 0.0 32.5 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.2 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.4 0.3 3.4 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 13.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.2 24.6 10.3 59.5 14.5 22.4 30.9 18.3 30.7 5.4 5.4 34.2 0.6 3.2 5.8 2.0 0.7 0.4 1.0 0.2 0.0 13.3 52.7 45.3 2.7 0.0 2.5 3.7 10.4 0.1 1.8 0.1 5.9 0.0 0.2 0.3 3.9 1.7 0.0 0.0 19.0 0.0 0.2 1.9 0.0 0.3 0.0 0.2 0.0 0.0 0.1 18.5 16.6 0.0 16.2 0.6 1.5 0.0 2.8 0.8 42.7 3.7 0.0 496.8 2.1 1.0 1.0 0.0 0.0 0.0 0.1 0.5 0.0 0.3 1.5 17.5 0.0 0.2 1.4 0.2 1.0 0.0 1.7 0.3 1.2 0.1 0.1 0.2 STAR STARD1 ENSG00000147465 "Steroidogenic acute regulatory protein" P49675 8 38142700-38150992 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Lipid transport, Steroidogenesis, Transport" "Congenital adrenal hyperplasia, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "adrenal gland: 5073.8" "Cell type enriched" "Detected in some" 44 "Theca cells: 2243.4" "Group enriched" "Detected in some" 4 "head and neck cancer: 1.0;lung cancer: 0.8;ovarian cancer: 1.4;testis cancer: 3.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "basophil: 2.4" "Lineage enriched" "Detected in single" 10 "granulocytes: 2.4" "Cell line enriched" "Detected in some" 5 "K-562: 436.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA023644, HPA027318, CAB032598" Enhanced NA NA "Cluster 10: Basophils - Unknown function" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 1: K-562 - Erythropoiesis" "Cluster 52: Non-specific - Transcription" "CAB032598: AB_2115937, HPA023644: AB_10598916, HPA027318: AB_10601574" "unprognostic (1.60e-4)" "unprognostic (3.20e-2)" "unprognostic (9.17e-2)" "unprognostic (3.28e-2)" "unprognostic (9.22e-2)" "unprognostic (1.32e-3)" "unprognostic (1.96e-2)" "unprognostic (2.12e-5)" "unprognostic (3.30e-2)" "unprognostic (2.36e-1)" "unprognostic (1.77e-3)" "unprognostic (6.65e-2)" "unprognostic (4.75e-9)" "unprognostic (1.58e-1)" "unprognostic (1.33e-1)" "unprognostic (9.48e-2)" "unprognostic (6.16e-2)" 1.7 5073.8 2.3 3.1 1.6 2.1 0.4 1.6 3.3 1.0 0.7 0.5 0.2 0.5 0.6 2.1 6.3 0.2 0.9 1.5 4.5 0.4 1.2 0.5 0.9 3.8 3.3 497.1 0.9 0.0 2.2 0.5 4.1 0.5 0.1 0.6 1.8 0.3 0.4 5.0 0.6 0.4 1.4 1.0 0.7 88.2 3.0 3.0 0.4 0.0 1.9 0.5 3.2 1.5 0.1 0.0 0.8 0.2 0.3 3.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.7 0.1 0.1 0.0 0.1 0.1 0.5 0.0 0.1 0.0 88.9 0.8 5.3 1.3 3.8 0.1 12.4 0.3 0.1 0.1 0.8 0.0 0.3 436.1 0.2 0.0 0.0 0.4 43.7 9.6 0.1 0.1 0.0 0.0 0.0 0.0 0.2 1.2 1.2 0.2 0.0 0.2 0.0 0.1 43.0 1.5 0.1 0.0 0.2 0.1 0.2 0.2 0.0 0.3 9.3 0.2 2.4 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.3 0.1 0.0 0.0 0.2 0.0 2.3 1.6 1.6 3.3 1.5 4.5 3.8 3.3 4.1 1.4 3.0 1.5 0.0 0.0 0.0 0.7 0.1 9.4 0.7 0.8 4.0 1.1 0.1 1.1 0.6 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.1 1.9 10.7 0.6 0.0 0.0 1.4 0.0 0.0 25.7 0.0 0.3 0.0 1.4 0.0 0.0 0.2 0.0 2.8 0.0 0.0 0.0 0.7 10.2 50.1 0.2 3.6 0.0 0.0 0.6 0.0 0.5 0.3 0.1 0.0 4.1 0.0 0.2 0.0 0.0 0.4 0.6 0.0 0.2 3.0 4.8 0.8 1.7 11.2 0.1 0.1 2243.4 0.0 0.1 STK10 "LOK, PRO2729" ENSG00000072786 "Serine/threonine kinase 10" O94804 5 172042079-172188224 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 76.5;lymphoid tissue: 45.2" "Cell type enhanced" "Detected in all" "dendritic cells: 107.7;Kupffer cells: 91.4;NK-cells: 171.0;T-cells: 81.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "WM-115: 143.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015083, CAB020840" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 16000 "Cluster 51: Monocytes - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 17: WM-115 - Nervous system development" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Plasma membrane" "CAB020840: , HPA015083: AB_2669151" "unprognostic (1.17e-1)" "unprognostic (5.43e-2)" "prognostic favorable (2.76e-4)" "unprognostic (2.88e-1)" "unprognostic (6.96e-3)" "unprognostic (1.02e-1)" "unprognostic (5.25e-3)" "unprognostic (3.07e-2)" "unprognostic (1.07e-1)" "unprognostic (1.03e-1)" "unprognostic (2.65e-1)" "unprognostic (3.43e-1)" "prognostic unfavorable (1.63e-4)" "unprognostic (1.09e-1)" "unprognostic (1.01e-2)" "unprognostic (3.10e-1)" "unprognostic (1.84e-1)" 14.9 5.7 3.1 37.1 3.6 76.5 11.4 18.4 5.6 4.5 3.5 8.5 8.4 4.9 1.7 5.6 4.7 13.2 7.6 3.1 4.0 5.9 6.2 18.4 44.1 6.2 4.4 2.5 7.2 3.1 4.1 17.2 5.8 4.4 6.9 1.2 4.7 3.5 5.0 14.2 16.0 7.8 5.4 45.2 11.1 14.0 6.4 20.6 5.3 5.5 25.0 14.9 5.2 7.0 22.2 20.2 12.7 18.8 14.7 18.1 31.5 28.4 24.0 20.2 18.9 10.6 28.6 26.8 14.6 35.6 42.3 25.4 5.7 35.1 13.5 35.0 9.3 32.1 8.2 6.1 20.2 32.7 36.4 17.4 7.5 27.4 23.1 7.5 18.3 10.4 3.0 36.2 14.7 35.7 23.5 73.4 5.0 11.3 16.1 38.2 9.9 17.7 8.2 27.6 8.3 10.2 16.4 22.5 77.9 15.6 8.2 68.7 24.8 22.3 11.3 15.8 15.5 30.2 48.4 17.1 29.4 49.8 143.3 16.7 26.5 23.4 36.5 46.3 26.9 10.0 19.3 26.3 22.5 8.1 11.0 20.0 48.9 16.9 71.8 7.1 26.7 44.0 3.1 3.6 18.4 5.6 3.1 4.0 6.2 4.4 5.8 5.4 6.4 7.0 35.8 3.2 11.2 1.6 40.5 6.6 8.4 7.2 5.7 4.3 3.3 3.7 3.8 5.7 6.1 1.8 6.2 4.1 107.7 11.8 1.9 4.5 2.5 3.5 4.6 23.9 12.0 11.8 8.5 6.2 27.2 9.3 20.9 7.1 28.4 3.6 18.2 2.3 36.3 47.1 7.9 19.9 2.0 91.4 43.8 3.2 2.8 61.3 8.8 32.8 49.8 2.1 171.0 10.1 14.4 10.7 11.8 1.5 42.8 11.7 6.5 2.0 6.1 2.2 13.1 5.1 10.2 5.3 7.8 2.6 4.1 5.1 81.4 11.4 5.3 10.7 STXBP1 "hUNC18, MUNC18-1, rbSec1, UNC18" ENSG00000136854 "Syntaxin binding protein 1" P61764 9 127579370-127696027 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 174.5;pituitary gland: 66.4;retina: 214.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 131.0;Cone photoreceptor cells: 156.4;Excitatory neurons: 243.2;Inhibitory neurons: 157.5;Rod photoreceptor cells: 155.6" "Cancer enhanced" "Detected in all" "melanoma: 39.6" "Region enhanced" "Detected in many" "cerebral cortex: 174.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SCLC-21H: 144.1;SK-MEL-30: 131.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008209, HPA023483, CAB034434" Enhanced Approved Nucleoplasm,Cytosol NA NA 29000 "Cluster 32: T-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Cytosol" "CAB034434: AB_2196699, HPA008209: AB_1857624, HPA023483: AB_1857625" "unprognostic (2.32e-2)" "unprognostic (7.33e-2)" "unprognostic (3.85e-2)" "prognostic unfavorable (4.78e-4)" "unprognostic (1.80e-1)" "prognostic unfavorable (1.47e-4)" "prognostic unfavorable (5.73e-4)" "unprognostic (2.87e-2)" "unprognostic (2.31e-1)" "unprognostic (3.08e-3)" "prognostic favorable (9.81e-4)" "unprognostic (1.30e-2)" "unprognostic (1.67e-1)" "unprognostic (2.68e-2)" "unprognostic (5.51e-2)" "unprognostic (7.66e-2)" "unprognostic (3.36e-3)" 27.5 28.8 22.8 7.8 33.2 1.1 21.0 38.6 174.5 21.8 0.0 15.9 5.5 24.1 7.1 10.4 32.3 11.4 24.0 48.3 12.2 14.1 3.1 32.1 6.0 48.7 0.0 25.2 24.8 15.0 66.4 14.1 33.1 10.5 8.4 214.2 15.6 10.4 9.0 11.4 9.3 21.0 0.0 10.4 13.3 9.1 6.8 5.8 20.1 9.2 7.0 15.4 16.4 27.2 13.2 27.1 25.5 28.8 56.6 48.3 23.2 45.0 22.9 26.6 23.3 1.5 15.4 13.1 24.2 29.7 74.2 4.7 22.6 28.1 32.7 29.8 15.4 17.1 69.7 4.9 28.5 1.8 14.6 36.6 15.4 70.0 33.7 42.6 32.2 43.4 17.8 19.6 45.5 24.5 12.5 5.2 21.5 21.4 35.9 7.5 12.1 31.3 22.0 0.6 144.1 69.9 72.9 37.2 131.9 22.5 5.8 5.6 47.5 30.0 15.1 59.9 17.4 40.2 73.2 17.4 59.2 18.9 28.4 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.6 0.9 0.1 0.0 0.3 0.4 0.0 0.0 0.0 0.1 0.0 0.2 22.8 33.2 38.6 174.5 48.3 12.2 48.7 0.0 33.1 0.0 6.8 27.2 24.3 25.6 70.7 34.0 1.2 11.6 10.1 8.4 12.5 131.0 10.5 8.0 15.2 1.5 9.2 3.7 156.4 2.7 1.1 0.5 7.9 13.1 2.2 8.3 14.7 28.9 45.6 4.0 243.2 8.4 5.9 18.7 3.1 7.0 5.1 5.0 26.7 1.4 4.4 84.1 157.5 10.2 8.2 2.5 5.6 2.2 20.5 3.0 10.6 45.0 0.6 27.0 0.0 61.3 39.0 5.3 0.0 44.4 1.6 10.8 0.1 8.9 15.9 155.6 13.1 9.5 11.2 40.6 16.9 2.9 7.5 24.5 2.3 17.7 0.9 7.1 STXBP2 "Hunc18b, UNC18B" ENSG00000076944 "Syntaxin binding protein 2" Q15833 19 7636881-7647873 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Exocytosis, Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 194.2" "Cell type enhanced" "Detected in many" "Kupffer cells: 262.5;Macrophages: 249.1;monocytes: 368.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 248.6;classical monocyte: 471.0;eosinophil: 295.6;intermediate monocyte: 604.8;myeloid DC: 239.7;neutrophil: 356.2;non-classical monocyte: 893.3" "Group enriched" "Detected in all" 6 "dendritic cells: 239.7;granulocytes: 356.2;monocytes: 893.3" "Cell line enhanced" "Detected in many" "HMC-1: 244.8;U-937: 224.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA015564, HPA063868" Approved Enhanced Cytosol No No 870000 "Cluster 51: Monocytes - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol "HPA015564: AB_1857626, HPA063868: AB_2685136" "unprognostic (1.20e-2)" "unprognostic (6.17e-3)" "unprognostic (2.85e-2)" "prognostic favorable (2.29e-4)" "unprognostic (2.54e-1)" "unprognostic (1.75e-3)" "prognostic unfavorable (4.65e-4)" "unprognostic (4.22e-3)" "unprognostic (2.35e-1)" "unprognostic (6.25e-2)" "unprognostic (1.79e-1)" "unprognostic (4.99e-2)" "unprognostic (1.51e-1)" "unprognostic (4.62e-2)" "unprognostic (2.85e-1)" "prognostic favorable (7.68e-4)" "prognostic favorable (5.13e-6)" 24.2 22.8 5.2 65.9 6.3 194.2 24.3 4.8 10.9 22.2 9.3 52.5 67.4 8.4 33.2 73.1 27.7 28.4 7.5 5.1 6.2 62.4 49.0 89.6 51.0 8.3 6.6 5.3 86.7 36.1 29.4 36.3 7.9 52.1 37.0 4.2 79.4 22.8 2.9 52.3 63.9 14.6 6.7 162.2 71.9 74.9 8.8 85.3 52.0 3.0 34.6 34.6 34.8 9.3 113.0 39.1 0.9 0.5 0.0 0.9 75.6 14.2 1.5 2.7 7.4 92.5 69.6 29.6 55.4 11.3 49.5 75.5 4.1 67.5 2.7 124.1 46.9 127.8 49.7 55.8 63.6 83.2 244.8 4.4 67.4 13.4 38.0 0.3 58.5 74.7 81.4 98.5 0.0 70.9 41.2 193.2 28.7 72.7 68.0 41.8 0.3 114.7 55.0 128.1 11.5 0.6 34.0 49.6 2.2 35.6 61.9 212.7 61.7 0.4 21.8 1.5 0.8 108.4 58.6 38.8 1.2 224.8 2.7 248.6 471.0 295.6 69.9 604.8 56.7 47.3 52.7 63.8 239.7 52.2 36.6 44.3 356.2 74.7 893.3 91.5 78.9 306.9 5.2 6.3 4.8 10.9 5.1 6.2 8.3 6.6 7.9 6.7 8.8 9.3 2.1 0.0 7.7 0.7 44.1 23.6 48.2 105.1 18.8 6.0 38.0 22.9 0.9 31.5 68.5 35.0 2.1 97.7 56.2 181.4 33.2 100.3 99.9 32.5 5.4 6.7 59.8 38.3 0.6 118.8 123.2 5.7 150.3 47.6 71.8 34.6 16.4 19.6 168.4 0.0 0.4 108.2 105.8 262.5 46.6 233.5 1.8 249.1 14.2 1.0 368.2 0.9 72.1 0.0 0.0 132.8 152.6 1.9 54.7 49.1 171.7 75.9 42.5 4.0 6.6 1.0 8.6 45.7 20.2 35.3 21.3 153.0 47.7 6.0 79.3 68.7 SULT4A1 "hBR-STL-1, SULTX3" ENSG00000130540 "Sulfotransferase family 4A member 1" Q9BR01 22 43824509-43862513 "Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 33 "brain: 90.2" "Cell type enhanced" "Detected in some" "Bipolar cells: 23.0;Early spermatids: 23.7;Excitatory neurons: 53.1;Horizontal cells: 23.5;Inhibitory neurons: 55.2;Late spermatids: 29.4;Rod photoreceptor cells: 19.5" "Cancer enhanced" "Detected in many" "testis cancer: 6.3" "Region enhanced" "Detected in many" "cerebral cortex: 90.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003129 Enhanced NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA003129: AB_1080130" "unprognostic (2.61e-3)" "unprognostic (1.05e-2)" "unprognostic (2.62e-1)" "unprognostic (6.30e-2)" "unprognostic (6.12e-3)" "unprognostic (1.32e-1)" "unprognostic (1.63e-1)" "unprognostic (8.74e-2)" "unprognostic (2.82e-1)" "unprognostic (2.48e-4)" "unprognostic (1.91e-2)" "unprognostic (6.10e-2)" "unprognostic (7.59e-4)" "unprognostic (7.89e-2)" "unprognostic (1.22e-1)" "unprognostic (8.20e-3)" "unprognostic (8.34e-3)" 0.0 2.7 22.3 0.3 23.2 0.0 0.0 1.6 90.2 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 22.2 21.7 0.1 0.0 0.0 0.0 9.6 0.0 0.0 0.2 0.0 2.5 0.0 8.0 0.0 0.2 2.2 0.0 0.0 0.0 0.0 0.6 0.4 0.0 0.0 0.4 0.8 5.9 0.0 0.0 0.0 0.0 0.0 0.3 25.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.3 23.2 1.6 90.2 22.2 21.7 9.6 0.0 8.0 0.0 5.9 25.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.3 0.0 23.0 0.2 0.5 1.4 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 23.7 1.1 1.3 0.4 0.0 0.0 53.1 0.0 0.0 0.4 0.0 3.7 0.0 1.9 0.0 0.0 0.1 23.5 55.2 0.0 0.0 0.0 0.0 29.4 0.0 0.1 0.0 10.3 0.0 4.0 0.0 8.0 6.2 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.2 19.5 0.0 0.0 0.2 3.0 5.7 0.0 0.0 0.0 0.0 3.2 0.0 0.0 TACC3 "ERIC-1, ERIC1, maskin, Tacc4" ENSG00000013810 "Transforming acidic coiled-coil containing protein 3" Q9Y6A5 4 1712891-1745171 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 58.9;lymphoid tissue: 52.4;testis: 50.6" "Cell type enhanced" "Detected in many" "Early spermatids: 70.4;Hofbauer cells: 43.9;Late spermatids: 69.9;Spermatocytes: 94.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005781, HPA006050, CAB010111, HPA022039" Enhanced Enhanced "Vesicles,Mitotic spindle,Centriolar satellite,Cytosol" Yes Yes 11000 "Cluster 5: Granulocytes - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Mitotic spindle, Centriolar satellite, Cytosol" Vesicles "CAB010111: AB_628323, HPA005781: AB_1857724, HPA006050: AB_2667505, HPA022039: AB_1857725" "unprognostic (2.95e-1)" "unprognostic (1.18e-1)" "unprognostic (7.71e-2)" "unprognostic (4.35e-2)" "unprognostic (6.58e-2)" "unprognostic (1.84e-2)" "prognostic unfavorable (3.30e-4)" "unprognostic (1.10e-3)" "unprognostic (4.61e-2)" "unprognostic (9.12e-2)" "unprognostic (2.91e-2)" "unprognostic (2.26e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (4.66e-2)" "unprognostic (2.09e-1)" "unprognostic (4.44e-3)" "unprognostic (9.75e-2)" 5.3 3.9 4.2 24.9 4.3 58.9 3.5 5.2 5.3 3.6 5.2 10.3 6.6 3.3 4.8 14.9 2.8 4.2 3.3 4.5 4.4 2.7 3.5 6.5 43.2 4.8 5.3 2.2 1.4 2.3 2.6 8.7 4.8 2.4 10.6 1.9 3.9 2.5 2.0 6.4 12.9 6.4 4.2 22.1 6.4 50.6 5.1 52.4 2.8 3.4 39.3 5.0 5.4 4.7 106.7 88.7 129.5 72.2 6.7 15.2 72.9 114.6 62.1 135.4 87.6 93.5 122.8 133.8 48.0 65.4 149.9 71.4 142.5 86.8 131.1 59.8 77.0 113.8 67.2 85.8 5.9 146.6 85.5 5.2 5.7 85.6 46.0 26.0 102.2 110.3 106.3 90.8 123.8 87.1 207.5 204.0 139.3 89.2 111.6 139.1 90.5 55.0 73.8 125.5 99.8 62.8 70.1 42.3 33.1 95.2 83.3 90.5 56.4 75.4 90.0 65.4 176.7 69.5 102.5 207.1 43.2 141.1 109.1 45.5 30.0 37.9 8.5 12.5 11.1 7.8 16.5 11.5 15.3 10.8 28.3 13.1 91.8 12.2 9.6 8.3 42.5 32.5 4.2 4.3 5.2 5.3 4.5 4.4 4.8 5.3 4.8 4.2 5.1 4.7 6.0 0.0 6.7 2.0 16.5 2.2 1.2 3.2 1.2 1.7 2.4 3.0 2.6 2.8 3.4 9.2 8.4 19.5 6.4 11.2 0.0 2.2 70.4 4.2 2.8 5.2 1.2 37.2 2.3 0.7 20.4 6.0 12.8 4.3 5.1 24.5 8.9 5.1 43.9 5.0 3.2 9.5 4.1 23.2 10.8 69.9 2.8 34.1 0.0 4.7 24.4 1.4 6.2 0.5 0.8 2.9 4.2 2.6 18.0 1.3 2.6 2.8 0.9 2.7 6.6 2.0 4.8 94.3 37.7 12.8 1.4 4.0 23.2 2.2 16.1 2.7 TBC1D2 "Armus, PARIS1, TBC1D2A" ENSG00000095383 "TBC1 domain family member 2" Q9BYX2 9 98199011-98255649 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 57.7;Oligodendrocytes: 64.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 27.5" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 77.0;HaCaT: 98.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA030871, HPA076521" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA Yes "Cluster 25: Monocytes - Inflammatory response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Plasma membrane, Cytosol" "HPA030871: AB_10670046, HPA076521: " "unprognostic (2.32e-2)" "unprognostic (1.11e-1)" "unprognostic (1.06e-2)" "unprognostic (6.36e-3)" "unprognostic (2.02e-2)" "prognostic unfavorable (2.77e-4)" "unprognostic (1.86e-1)" "unprognostic (2.11e-1)" "unprognostic (1.74e-1)" "unprognostic (9.21e-3)" "unprognostic (6.40e-3)" "unprognostic (2.30e-1)" "unprognostic (6.07e-2)" "unprognostic (4.32e-1)" "prognostic unfavorable (5.62e-4)" "unprognostic (1.30e-2)" "unprognostic (4.30e-1)" 8.8 5.3 11.1 5.7 16.0 13.1 7.8 12.3 26.0 10.8 8.5 8.6 12.6 4.4 1.5 37.4 5.5 4.0 3.7 10.6 12.9 6.4 19.8 32.0 3.8 14.9 14.9 2.9 3.0 3.5 4.4 7.2 16.4 12.0 4.4 3.4 14.7 6.1 4.3 24.3 10.1 2.8 11.4 9.4 7.0 3.4 23.3 3.0 8.1 1.4 4.9 11.7 17.3 23.9 77.0 10.8 0.5 2.5 8.2 15.9 24.3 33.2 18.4 23.8 19.6 6.9 32.8 1.3 24.7 19.6 5.2 98.1 0.7 36.8 8.3 2.6 1.4 0.7 38.0 5.4 37.6 1.7 2.9 21.7 59.8 23.6 58.7 41.5 8.6 2.1 2.4 1.0 19.0 9.9 0.4 4.6 1.6 7.4 6.2 1.2 4.8 0.2 36.0 46.7 0.9 1.4 11.3 24.4 3.4 1.7 8.1 2.6 51.7 28.8 8.6 4.8 13.6 1.6 1.5 0.6 29.0 2.9 3.2 2.1 27.5 8.4 2.5 15.3 1.8 1.2 3.8 2.2 10.0 0.8 1.6 1.9 11.9 1.2 12.3 1.3 5.5 10.8 11.1 16.0 12.3 26.0 10.6 12.9 14.9 14.9 16.4 11.4 23.3 23.9 2.9 57.7 12.5 5.2 2.4 8.3 18.5 30.4 21.6 3.3 2.7 5.6 0.7 4.3 23.3 3.7 0.0 21.5 0.9 16.2 3.9 3.3 1.8 4.6 3.7 5.0 7.7 0.4 4.6 3.2 10.9 2.4 6.1 10.3 0.0 0.6 1.1 6.1 32.0 1.7 5.4 12.6 18.3 16.2 1.8 1.2 1.8 18.3 3.6 4.7 7.5 4.4 3.1 12.1 64.9 14.4 10.7 0.7 1.7 9.2 16.4 3.2 10.8 2.4 0.0 1.8 3.4 2.1 3.0 29.8 10.9 17.4 2.4 0.7 5.7 17.1 TBC1D22B "C6orf197, dJ744I24.2, FLJ20337" ENSG00000065491 "TBC1 domain family member 22B" Q9NU19 6 37257772-37332970 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 80.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027908, HPA027909, HPA027910" Uncertain Uncertain Nucleoplasm,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 1: Pancreatic cells - Digestion" "Nucleoplasm, Cytosol" "HPA027908: AB_10602073, HPA027909: AB_10601857, HPA027910: AB_10602203" "unprognostic (9.83e-2)" "unprognostic (5.36e-2)" "unprognostic (2.17e-2)" "prognostic unfavorable (8.15e-5)" "unprognostic (2.70e-1)" "unprognostic (1.45e-1)" "unprognostic (2.29e-2)" "unprognostic (1.44e-1)" "unprognostic (9.48e-2)" "unprognostic (6.06e-3)" "unprognostic (3.10e-2)" "unprognostic (1.46e-1)" "unprognostic (3.53e-3)" "unprognostic (9.87e-2)" "unprognostic (2.71e-1)" "unprognostic (3.19e-1)" "unprognostic (9.73e-2)" 5.8 12.1 8.3 5.1 8.4 18.3 5.7 8.3 8.2 7.9 8.8 6.5 7.9 6.4 7.4 14.1 8.2 5.9 7.4 8.3 8.0 8.6 6.1 8.0 5.8 7.7 8.1 9.4 12.8 10.7 6.7 6.0 7.9 8.2 7.7 7.7 11.8 5.5 15.0 15.2 8.5 6.7 7.1 7.2 7.5 10.0 8.5 13.5 7.7 7.8 7.1 7.5 9.3 8.1 13.2 5.5 9.9 10.9 9.1 9.1 14.2 7.2 15.0 13.2 16.2 12.6 8.5 12.3 7.4 9.2 17.9 8.9 12.7 11.6 14.8 19.9 10.4 19.5 9.0 17.2 13.0 11.1 15.9 7.8 16.6 13.0 15.4 12.6 18.9 20.4 22.5 3.1 9.6 11.9 16.6 8.4 13.0 15.0 5.1 10.7 9.1 9.6 13.6 9.5 13.0 8.4 7.9 11.2 14.3 13.3 8.2 19.7 18.4 8.0 12.2 5.5 9.6 11.1 12.4 80.8 5.5 16.5 12.6 1.4 2.6 4.4 2.3 3.5 2.7 1.7 2.6 2.3 4.0 2.0 2.8 2.4 1.1 3.0 1.5 1.1 1.9 2.6 8.3 8.4 8.3 8.2 8.3 8.0 7.7 8.1 7.9 7.1 8.5 8.1 4.1 3.2 5.6 17.9 6.3 8.2 8.5 7.5 8.0 5.0 6.0 3.7 5.8 7.2 10.1 1.8 4.2 6.3 4.6 15.1 3.9 12.3 5.6 10.6 3.6 4.9 1.8 10.5 20.3 15.4 9.2 4.2 3.1 8.1 5.7 5.0 3.6 3.9 5.8 0.0 22.0 4.9 10.2 4.4 7.8 5.0 3.1 4.1 1.8 6.5 6.0 3.6 6.2 14.1 24.1 15.0 6.8 1.2 5.6 10.0 11.2 9.0 15.8 4.5 0.0 4.2 3.6 6.5 6.4 10.8 15.9 6.7 6.6 3.2 6.3 11.2 TECR "GPSN2, MRT14, SC2, TER" ENSG00000099797 "Trans-2,3-enoyl-CoA reductase" Q9NZ01 19 14517085-14565980 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Sphingolipid metabolism" Oxidoreductase "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 1013.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029780, HPA056488" Supported Supported "Endoplasmic reticulum" NA NA 10000 "Cluster 20: T-cells - T-cell receptor" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 10: Non-specific - Unknown function" "Endoplasmic reticulum" "HPA029780: AB_10603348, HPA056488: AB_2683149" "unprognostic (9.73e-2)" "unprognostic (3.69e-3)" "unprognostic (1.55e-1)" "unprognostic (8.08e-3)" "unprognostic (1.20e-1)" "unprognostic (3.96e-2)" "unprognostic (3.68e-2)" "unprognostic (1.24e-1)" "unprognostic (1.36e-1)" "unprognostic (9.16e-2)" "unprognostic (1.29e-1)" "unprognostic (5.05e-2)" "unprognostic (3.65e-3)" "unprognostic (2.53e-3)" "unprognostic (2.34e-1)" "unprognostic (2.07e-2)" "prognostic unfavorable (2.60e-4)" 102.7 162.6 189.0 43.1 201.7 74.2 100.4 220.8 237.5 156.8 216.5 78.5 106.1 53.2 103.2 373.2 87.1 49.7 78.4 180.1 200.0 112.2 133.9 67.8 55.7 209.6 191.2 80.9 105.5 306.1 78.7 68.0 212.2 85.7 59.3 82.8 222.3 83.5 366.3 263.5 95.9 36.7 207.6 75.4 81.7 182.7 199.9 65.8 92.7 209.6 85.3 51.6 185.9 230.2 220.5 162.1 149.5 169.6 214.7 97.2 156.9 62.8 175.2 196.3 242.9 225.3 246.2 113.8 127.4 134.2 152.4 328.8 158.1 254.3 84.0 192.3 165.9 193.7 225.4 254.6 129.7 139.5 143.7 144.9 201.8 174.3 96.1 98.4 93.7 169.2 128.9 391.5 104.0 289.3 170.1 248.3 155.6 556.1 227.6 154.4 96.1 521.1 275.1 115.8 183.2 113.0 103.1 278.4 139.6 77.2 151.3 274.4 55.2 160.5 66.8 141.0 212.6 118.4 119.8 122.7 163.8 212.6 162.2 55.6 72.7 52.5 137.8 106.4 148.8 100.1 180.1 159.1 124.2 99.1 207.1 164.5 32.7 183.7 83.9 137.1 290.1 170.9 189.0 201.7 220.8 237.5 180.1 200.0 209.6 191.2 212.2 207.6 199.9 230.2 60.4 73.7 71.1 47.7 87.6 169.5 227.5 297.9 125.7 90.8 161.1 155.6 52.9 120.1 221.5 165.5 123.0 509.5 88.1 159.2 56.7 166.2 443.9 102.2 40.1 64.7 100.0 80.1 15.3 225.1 525.5 81.8 89.7 64.2 36.1 90.1 73.2 143.1 188.0 112.7 19.2 144.0 199.4 113.8 99.3 1013.1 72.7 77.8 163.7 18.7 61.6 577.9 103.0 12.5 46.5 104.8 128.2 60.2 206.1 110.2 343.2 202.9 213.1 177.5 65.7 68.4 286.7 215.0 134.2 255.3 239.7 486.2 117.7 116.0 216.2 196.5 TEX264 "FLJ13935, ZSIG11" ENSG00000164081 "Testis expressed 264, ER-phagy receptor" Q9Y6I9 3 51662693-51704323 "Plasma proteins, Predicted intracellular proteins" "Autophagy, DNA damage, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 374.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005002, HPA017739" Enhanced Approved Nucleoli,Cytosol "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 43: Testis - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoli, Cytosol" "CAB005002: AB_425976, HPA017739: AB_1857910" "unprognostic (2.80e-3)" "unprognostic (1.05e-2)" "unprognostic (2.69e-1)" "unprognostic (2.79e-3)" "unprognostic (8.11e-2)" "unprognostic (8.26e-3)" "unprognostic (2.05e-1)" "unprognostic (3.06e-3)" "unprognostic (2.30e-1)" "unprognostic (5.19e-2)" "prognostic favorable (5.67e-4)" "unprognostic (1.83e-1)" "prognostic favorable (7.95e-9)" "unprognostic (4.99e-2)" "unprognostic (3.65e-1)" "unprognostic (3.17e-1)" "unprognostic (4.67e-2)" 34.7 73.4 43.5 23.1 46.5 22.3 35.6 48.7 51.7 39.0 53.1 41.5 39.0 34.2 41.2 41.1 44.0 39.7 41.4 43.8 47.2 67.6 65.3 29.8 33.5 47.2 45.5 31.3 54.3 88.5 26.2 29.4 46.4 45.1 34.5 20.4 58.7 46.9 34.2 69.3 37.6 26.3 46.3 40.9 46.7 111.5 45.9 29.1 48.7 29.6 26.3 35.9 34.9 48.4 36.5 65.5 11.6 59.3 116.8 56.4 23.5 31.0 72.0 50.1 50.1 35.2 84.2 51.6 21.9 44.1 84.2 34.7 32.7 61.6 23.7 42.0 51.9 49.6 40.2 47.8 104.0 31.5 53.6 74.8 96.9 56.3 57.1 45.3 36.9 39.0 26.6 87.7 51.9 42.1 50.9 73.3 12.6 59.8 72.7 24.3 15.3 98.7 79.7 50.1 16.5 26.8 37.4 101.5 48.0 15.7 49.6 66.0 27.3 49.8 20.8 53.0 41.2 61.0 71.3 26.4 61.5 65.9 50.9 99.2 110.1 69.3 119.7 115.6 120.3 98.6 122.6 113.6 104.6 102.4 100.9 103.1 23.5 76.1 115.6 92.4 159.9 139.9 43.5 46.5 48.7 51.7 43.8 47.2 47.2 45.5 46.4 46.3 45.9 48.4 63.6 35.3 21.9 12.4 36.7 34.8 46.7 123.9 45.5 33.5 69.9 68.2 24.4 65.8 68.2 99.3 58.4 142.9 52.3 70.3 62.6 83.1 57.7 44.9 31.8 54.8 32.9 24.8 6.5 75.7 88.9 41.4 29.0 48.2 16.5 45.3 38.9 63.1 105.4 42.1 9.1 56.5 118.0 48.3 45.5 61.2 51.0 47.8 65.8 8.4 56.1 62.6 89.6 7.5 12.3 59.6 76.4 48.9 36.0 45.6 137.6 126.7 49.7 55.4 26.3 30.8 30.7 374.8 111.7 46.3 35.4 76.3 61.9 110.4 86.0 49.9 TFAP2E AP2E ENSG00000116819 "Transcription factor AP-2 epsilon" Q6VUC0 1 35573314-35595328 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 9.2" "Cell type enhanced" "Detected in some" "Bipolar cells: 9.8;Excitatory neurons: 9.0;Inhibitory neurons: 9.8;Oligodendrocytes: 11.3;Rod photoreceptor cells: 5.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NB-4: 4.6;SK-MEL-30: 1.7;U-937: 3.6" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 24: NB-4 - Immune response" "Cluster 56: Bipolar cells - Visual perception" "unprognostic (7.06e-4)" "unprognostic (1.96e-2)" "unprognostic (9.05e-2)" "unprognostic (2.29e-2)" "unprognostic (2.81e-2)" "unprognostic (1.34e-2)" "unprognostic (1.05e-2)" "unprognostic (3.34e-2)" "unprognostic (3.27e-2)" "unprognostic (9.39e-2)" "unprognostic (4.02e-1)" "unprognostic (7.45e-2)" "unprognostic (1.67e-15)" "unprognostic (2.03e-1)" "unprognostic (4.83e-1)" "unprognostic (3.48e-2)" "unprognostic (7.40e-2)" 1.0 0.6 3.0 0.9 2.8 1.5 1.0 9.2 4.0 3.5 0.2 1.1 0.1 1.3 0.3 1.2 2.5 0.2 0.9 2.6 2.2 1.1 0.3 1.3 0.9 2.8 2.3 2.5 0.6 0.0 3.2 0.2 3.0 1.7 0.1 4.4 1.0 0.1 0.4 5.2 1.2 0.0 2.4 1.9 1.0 2.2 2.4 0.3 0.5 0.0 0.3 0.8 3.1 5.1 0.2 0.2 0.2 0.1 0.1 0.1 0.8 0.1 0.0 0.0 0.0 0.5 0.1 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.6 0.2 0.5 0.4 0.3 0.0 0.0 0.6 0.1 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.2 0.3 4.6 0.3 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.2 0.3 0.2 0.1 1.7 0.1 0.4 1.4 0.1 0.1 0.7 0.4 0.1 0.8 0.4 0.0 0.1 3.6 0.5 0.5 0.8 0.5 0.9 0.3 0.3 0.4 0.5 0.8 0.4 0.4 0.2 0.8 0.0 0.9 0.4 0.3 0.8 0.5 3.0 2.8 9.2 4.0 2.6 2.2 2.8 2.3 3.0 2.4 2.4 5.1 0.2 0.0 1.3 4.9 0.2 3.7 0.1 0.3 0.0 9.8 0.5 0.5 0.4 0.0 0.8 0.0 2.1 0.4 0.9 0.1 0.0 0.2 0.5 0.3 0.4 0.3 0.0 0.0 9.0 0.0 0.0 0.4 2.6 0.5 0.0 0.1 0.4 0.2 1.0 0.0 9.8 0.0 0.0 1.0 0.0 1.0 2.1 0.6 1.8 1.9 0.5 0.3 3.1 3.5 11.3 0.2 0.3 0.7 0.3 0.1 0.1 0.0 0.2 5.6 0.0 0.2 0.4 2.4 0.4 0.0 4.4 0.1 0.9 0.1 0.4 0.2 THRSP "Lpgp, LPGP1, S14, SPOT14, THRP" ENSG00000151365 "Thyroid hormone responsive" Q92748 11 78063861-78068351 "Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 210.0;liver: 408.9" "Cell type enriched" "Detected in some" 6 "Hepatocytes: 128.4" "Cancer enhanced" "Detected in many" "liver cancer: 44.1" "Region enriched" "Detected in single" 6 "cerebellum: 2.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 13 "ASC diff: 76.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040642 Approved Approved Nucleoplasm NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 15: Hepatocytes - Hemostasis" Nucleoplasm "HPA040642: AB_10794878" "unprognostic (1.19e-1)" "unprognostic (2.88e-1)" "unprognostic (2.84e-1)" "unprognostic (2.73e-2)" "unprognostic (3.07e-1)" "unprognostic (9.91e-3)" "unprognostic (1.59e-2)" "unprognostic (9.60e-2)" "unprognostic (1.07e-2)" "unprognostic (8.23e-2)" "unprognostic (1.68e-1)" "unprognostic (2.58e-1)" "prognostic unfavorable (1.16e-4)" "unprognostic (9.64e-2)" "unprognostic (1.57e-1)" "prognostic favorable (3.28e-4)" "unprognostic (1.69e-3)" 210.0 5.9 0.1 0.4 0.1 0.0 95.3 2.7 0.3 0.1 0.0 2.6 0.0 0.1 0.4 0.3 1.0 3.4 18.6 0.2 0.0 4.6 408.9 0.1 0.7 0.0 0.2 0.1 3.6 15.5 0.1 0.0 0.4 0.1 0.2 1.5 48.9 2.3 8.2 33.7 4.6 0.5 0.0 0.1 0.7 0.1 0.0 0.2 5.7 3.3 0.0 0.8 1.1 0.1 0.0 0.0 0.0 0.0 76.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 2.7 0.3 0.2 0.0 0.0 0.2 0.4 0.0 0.0 0.1 2.2 0.0 0.0 0.0 0.8 0.1 0.1 0.0 0.0 2.3 21.1 11.2 0.1 4.3 0.0 0.0 0.0 0.0 0.2 0.0 9.8 0.0 0.0 0.6 0.1 0.4 0.0 2.7 0.5 0.0 0.0 0.1 0.0 0.3 0.0 0.1 2.9 128.4 0.0 0.0 0.4 0.3 0.0 3.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.1 0.0 1.8 0.0 0.7 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.1 TKT ENSG00000163931 Transketolase P29401 3 53224712-53256052 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 667.0" "Cell type enhanced" "Detected in all" "Kupffer cells: 696.7;monocytes: 624.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "classical monocyte: 447.9;eosinophil: 274.4;intermediate monocyte: 199.0;myeloid DC: 203.8;neutrophil: 375.3;non-classical monocyte: 242.6" "Group enriched" "Detected in all" 9 "dendritic cells: 203.8;granulocytes: 375.3;monocytes: 447.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029480, HPA029481" Enhanced Enhanced Nucleoplasm NA NA 150000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 20: HeLa - Mitochondria" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm "HPA029480: AB_10599307, HPA029481: AB_10601895" "unprognostic (5.05e-2)" "unprognostic (3.34e-2)" "unprognostic (1.02e-2)" "unprognostic (1.77e-2)" "unprognostic (2.06e-1)" "unprognostic (1.02e-2)" "prognostic unfavorable (7.21e-6)" "unprognostic (6.78e-2)" "unprognostic (1.70e-1)" "unprognostic (4.73e-2)" "unprognostic (3.06e-3)" "unprognostic (1.36e-2)" "unprognostic (2.08e-1)" "unprognostic (2.99e-1)" "unprognostic (1.07e-1)" "unprognostic (3.29e-1)" "unprognostic (9.90e-3)" 152.2 93.2 78.0 66.2 80.0 667.0 71.9 93.2 82.3 59.7 60.5 73.2 84.2 44.7 19.2 168.5 53.7 97.2 27.4 72.3 96.9 68.2 58.1 93.4 69.2 89.2 89.9 87.7 154.0 41.4 45.6 61.2 93.8 48.8 48.8 21.7 54.9 50.9 12.8 47.0 58.1 51.6 77.4 99.8 66.1 20.2 87.9 82.9 116.1 15.2 67.4 130.9 85.5 97.2 313.0 1542.9 216.0 241.5 470.8 570.8 439.5 206.2 353.8 348.8 330.8 430.1 779.3 388.5 96.8 302.9 673.3 438.3 377.9 775.8 102.4 131.0 210.3 259.6 1022.2 655.2 573.9 321.4 168.1 416.0 437.5 418.5 213.7 949.2 444.9 323.8 188.3 164.7 144.5 381.6 338.6 358.1 737.1 603.0 367.9 201.1 98.5 726.2 550.3 520.2 139.6 103.7 383.4 605.3 365.1 656.7 188.8 437.4 335.9 107.2 164.2 320.0 401.9 94.5 190.3 235.7 234.4 321.0 203.8 51.5 447.9 274.4 17.8 199.0 22.8 39.7 25.8 20.6 203.8 21.1 26.6 20.7 375.3 30.8 242.6 34.4 36.7 312.4 78.0 80.0 93.2 82.3 72.3 96.9 89.2 89.9 93.8 77.4 87.9 97.2 79.5 134.6 125.6 46.7 92.1 79.4 384.6 325.3 287.4 41.0 99.3 80.5 14.9 75.8 149.5 62.5 29.2 349.0 69.7 139.1 80.3 197.7 6.5 87.4 79.6 81.8 52.6 150.3 16.9 269.8 249.8 80.2 168.7 95.5 62.7 123.6 75.0 83.4 256.0 37.0 23.9 149.6 142.4 696.7 110.5 8.9 157.2 333.3 76.5 17.8 624.4 88.8 46.4 17.1 39.3 193.6 81.4 106.8 109.4 337.7 141.5 219.1 99.2 46.3 52.6 35.9 102.1 16.8 30.6 409.3 67.1 413.6 78.8 427.2 276.7 413.6 TLCD3A "CT120, FAM57A, FLJ22282" ENSG00000167695 "TLC domain containing 3A" Q8TBR7 17 732412-742968 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 71.7" "Group enriched" "Detected in some" 5 "Extravillous trophoblasts: 20.1;Hofbauer cells: 10.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 1.5" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" "unprognostic (1.46e-1)" "unprognostic (6.16e-2)" "unprognostic (5.64e-2)" "prognostic favorable (3.53e-6)" "unprognostic (1.11e-1)" "unprognostic (1.66e-1)" "unprognostic (1.32e-3)" "unprognostic (2.24e-2)" "unprognostic (1.98e-2)" "unprognostic (2.59e-2)" "unprognostic (9.40e-2)" "unprognostic (1.28e-1)" "prognostic unfavorable (1.44e-4)" "unprognostic (4.88e-2)" "unprognostic (1.60e-1)" "unprognostic (8.05e-2)" "unprognostic (1.39e-2)" 7.7 3.5 4.5 6.1 4.9 2.4 8.2 9.7 5.8 10.2 9.5 10.7 12.5 7.3 2.6 23.6 7.1 12.3 4.9 4.7 5.7 5.7 3.7 7.1 3.2 4.2 4.6 7.4 9.7 6.1 8.3 8.2 4.9 9.6 10.0 3.8 11.6 10.9 2.8 71.7 8.6 8.5 4.5 2.9 18.4 12.1 5.5 4.7 8.0 2.9 9.2 18.5 15.9 5.2 63.8 39.4 27.5 36.6 35.5 47.1 27.3 53.9 46.1 53.2 59.4 19.2 9.8 14.4 28.3 51.7 17.1 61.3 57.3 44.3 58.9 38.3 53.1 14.8 26.8 46.6 28.1 12.4 20.7 39.6 38.8 24.2 63.5 24.5 37.3 19.6 13.6 1.7 31.2 22.1 5.3 3.7 12.2 40.7 13.7 25.6 10.8 1.4 38.1 48.9 13.2 25.0 25.7 2.5 16.7 18.0 10.3 13.7 29.1 51.9 23.6 60.8 65.3 4.6 13.3 15.2 47.2 23.9 32.1 0.0 0.0 0.0 1.2 0.0 1.1 0.1 0.2 0.5 0.1 0.5 0.0 0.3 0.0 0.0 0.0 0.1 1.5 0.1 4.5 4.9 9.7 5.8 4.7 5.7 4.2 4.6 4.9 4.5 5.5 5.2 2.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 1.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 20.1 2.6 0.0 0.0 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 2.5 0.1 0.0 0.0 0.0 TM9SF4 "dJ836N17.2, KIAA0255" ENSG00000101337 "Transmembrane 9 superfamily member 4" Q92544 20 32109714-32167258 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064099 Approved NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 10: Non-specific - Unknown function" "HPA064099: AB_2685190" "unprognostic (3.10e-2)" "unprognostic (9.03e-3)" "unprognostic (1.02e-1)" "prognostic unfavorable (6.37e-6)" "unprognostic (3.85e-1)" "unprognostic (1.02e-1)" "prognostic unfavorable (2.15e-4)" "unprognostic (1.37e-1)" "unprognostic (3.23e-3)" "unprognostic (1.91e-1)" "unprognostic (6.65e-2)" "unprognostic (7.68e-2)" "unprognostic (6.98e-3)" "unprognostic (7.66e-2)" "unprognostic (1.45e-1)" "unprognostic (1.04e-1)" "unprognostic (4.23e-2)" 23.4 21.1 16.7 23.4 16.9 16.3 22.6 14.8 19.5 26.5 20.7 32.1 29.6 25.0 30.4 30.3 34.8 22.1 24.4 17.6 17.9 26.6 33.7 24.4 18.9 15.3 15.8 28.7 30.5 52.6 17.0 39.6 16.3 28.0 37.2 17.7 30.7 26.8 23.3 32.0 29.0 31.8 14.0 23.6 29.8 18.0 18.9 21.0 24.7 24.3 24.2 27.9 22.9 16.2 59.0 41.1 46.1 53.2 88.7 71.9 59.1 47.8 71.9 65.6 63.7 122.2 71.1 41.0 88.2 78.2 102.4 94.8 52.4 101.9 56.4 23.5 29.4 94.4 34.6 93.1 78.3 45.9 52.0 76.2 76.3 49.7 79.6 80.3 59.1 48.3 60.4 74.5 51.8 62.5 46.5 36.4 41.2 71.2 50.0 43.9 65.1 51.4 57.2 41.3 39.0 45.7 88.6 57.7 51.4 61.0 72.4 52.0 48.5 119.2 36.7 63.7 59.1 74.9 65.9 38.2 94.4 149.6 54.6 24.0 48.4 9.9 20.0 50.5 24.8 16.5 17.7 22.9 41.8 13.1 19.4 16.4 11.7 18.8 67.8 13.7 19.1 34.6 16.7 16.9 14.8 19.5 17.6 17.9 15.3 15.8 16.3 14.0 18.9 16.2 16.4 25.6 25.2 33.0 16.2 7.0 17.4 27.1 17.6 12.2 15.7 16.1 16.0 14.3 36.5 9.2 16.7 29.4 11.9 25.2 1.9 19.0 53.5 18.0 25.2 18.4 13.9 12.4 31.2 18.5 21.7 20.4 23.4 24.9 8.2 19.3 16.8 26.2 24.0 8.4 37.1 31.7 20.3 19.1 10.5 57.5 16.8 22.5 7.2 24.4 25.2 14.0 10.3 28.6 34.8 19.8 25.7 10.9 23.1 22.1 29.8 14.0 32.8 12.3 6.6 19.9 25.8 26.5 9.7 21.8 11.4 37.6 16.8 23.4 27.5 21.9 TMEM125 MGC17299 ENSG00000179178 "Transmembrane protein 125" Q96AQ2 1 43269983-43274002 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 75.7;pancreas: 89.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 121.8;Alveolar cells type 2: 136.9;Distal enterocytes: 72.7;Proximal enterocytes: 164.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 26.8;BEWO: 21.8;CACO-2: 20.6;CAPAN-2: 48.3;OE19: 31.3;SK-BR-3: 41.2;T-47d: 33.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015796 Approved Midbody,Cytosol Yes NA "Cluster 40: NK-cells - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 11: Alveolar cells - Smell perception" "Midbody, Cytosol" "HPA015796: AB_1858081" "unprognostic (2.53e-3)" "unprognostic (8.70e-2)" "unprognostic (1.27e-1)" "unprognostic (1.52e-1)" "unprognostic (3.14e-2)" "unprognostic (8.50e-2)" "unprognostic (8.37e-3)" "prognostic favorable (5.11e-5)" "unprognostic (3.39e-1)" "unprognostic (1.11e-1)" "unprognostic (7.76e-2)" "unprognostic (1.26e-1)" "prognostic favorable (2.91e-9)" "unprognostic (1.86e-2)" "unprognostic (2.19e-1)" "unprognostic (4.04e-1)" "unprognostic (5.16e-2)" 0.3 0.7 17.4 3.2 32.2 0.2 11.5 27.6 29.9 16.4 12.8 21.2 35.4 1.6 18.3 10.9 15.5 11.3 0.9 17.0 20.7 16.4 1.1 75.7 0.3 31.5 28.5 1.4 89.6 22.2 31.0 4.4 29.0 22.0 21.0 0.1 31.8 7.1 0.0 12.9 27.5 0.8 22.6 0.3 27.4 1.5 26.8 0.4 44.9 0.0 2.5 2.9 3.4 42.8 26.8 0.0 0.0 0.0 0.0 0.0 21.8 0.0 0.0 0.0 0.0 20.6 48.3 0.1 1.2 0.0 0.0 11.7 0.0 7.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 9.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 12.1 0.1 0.1 1.1 31.3 0.0 0.0 0.0 0.7 0.4 8.5 12.4 0.1 0.0 41.2 0.0 3.6 33.1 0.0 0.0 0.1 0.1 0.2 0.2 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 17.4 32.2 27.6 29.9 17.0 20.7 31.5 28.5 29.0 22.6 26.8 42.8 0.2 121.8 136.9 0.0 0.9 0.0 2.3 18.0 0.6 0.0 30.4 15.2 0.5 42.9 56.0 16.5 0.0 33.5 0.1 72.7 17.6 39.1 3.7 20.1 1.4 0.6 21.7 0.0 0.2 38.5 2.2 0.6 45.3 13.1 1.3 4.9 0.0 0.0 2.4 0.0 0.2 63.0 34.6 0.0 0.2 7.9 0.3 0.6 0.0 0.0 0.6 1.7 1.0 0.0 55.3 22.7 40.1 1.2 0.6 12.2 164.2 33.9 43.8 0.0 0.0 0.0 2.3 1.4 0.3 2.1 0.4 7.3 1.0 0.1 38.6 9.1 TMEM154 FLJ32028 ENSG00000170006 "Transmembrane protein 154" Q6P9G4 4 152618628-152680012 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 58.3;skin 1: 58.5" "Cell type enhanced" "Detected in many" "B-cells: 108.6;Basal keratinocytes: 74.2;Glandular and luminal cells: 75.0;granulocytes: 101.2;monocytes: 82.1;Squamous epithelial cells: 119.2;Suprabasal keratinocytes: 194.4" "Cancer enhanced" "Detected in many" "head and neck cancer: 6.9" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 8 "basophil: 403.7;eosinophil: 305.7;neutrophil: 477.5" "Lineage enriched" "Detected in many" 9 "granulocytes: 477.5" "Cell line enhanced" "Detected in many" "HBEC3-KT: 63.0;HMC-1: 71.1;Karpas-707: 55.6;U-266/70: 69.7;U-937: 56.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA019184, HPA055411" Uncertain Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Nuclear membrane" Nucleoplasm "HPA019184: AB_2670088, HPA055411: " "unprognostic (1.09e-1)" "unprognostic (3.56e-1)" "unprognostic (5.17e-2)" "unprognostic (3.09e-2)" "unprognostic (3.00e-1)" "unprognostic (1.52e-1)" "unprognostic (2.24e-1)" "unprognostic (2.96e-1)" "unprognostic (2.64e-1)" "unprognostic (1.65e-1)" "unprognostic (5.00e-3)" "unprognostic (7.67e-2)" "unprognostic (2.23e-3)" "unprognostic (1.50e-1)" "unprognostic (5.08e-2)" "unprognostic (1.13e-1)" "unprognostic (3.53e-1)" 3.1 0.5 0.3 17.2 0.7 18.6 4.3 0.6 1.7 5.7 0.5 3.1 2.6 1.6 0.7 58.3 1.4 5.1 0.8 0.4 0.7 0.6 5.9 5.1 14.3 0.8 0.6 0.2 1.0 0.3 0.8 3.8 1.1 2.0 2.6 0.2 6.9 2.3 0.4 58.5 3.6 1.8 0.7 12.4 5.9 0.2 1.0 6.2 3.6 1.9 26.4 11.6 7.9 1.0 32.1 0.1 0.3 0.1 0.5 8.7 14.1 8.0 29.1 8.5 16.2 0.4 4.2 32.5 3.3 7.6 9.3 22.8 0.0 63.0 15.5 0.1 0.1 1.8 0.5 0.0 8.9 25.7 71.1 8.3 29.7 27.1 23.4 0.0 21.4 19.7 0.1 55.6 0.7 2.3 10.1 8.0 1.6 0.1 7.8 1.2 0.1 0.2 47.5 19.4 0.1 1.2 2.2 6.2 1.0 8.4 1.0 17.8 8.6 1.2 5.1 0.7 11.1 69.7 26.0 18.1 11.7 56.6 6.6 403.7 37.8 305.7 4.9 38.2 9.2 51.6 10.9 7.9 19.6 45.1 10.7 7.4 477.5 0.8 43.7 2.5 22.5 17.2 0.3 0.7 0.6 1.7 0.4 0.7 0.8 0.6 1.1 0.7 1.0 1.0 6.5 12.8 19.3 0.0 108.6 74.2 9.0 23.6 20.5 0.1 8.8 4.8 1.7 0.0 20.9 22.0 2.1 25.0 9.8 0.9 0.0 6.4 0.1 31.9 13.4 6.7 1.2 6.6 0.5 3.7 14.5 5.2 8.2 75.0 101.2 0.1 0.7 4.6 4.5 3.3 0.3 0.7 14.2 9.8 15.7 0.2 0.6 28.2 5.4 15.9 82.1 0.1 5.2 3.5 0.1 21.5 7.1 0.0 45.7 5.4 0.0 0.3 60.5 0.7 0.0 3.0 3.6 0.1 0.5 119.2 194.4 25.9 28.6 0.5 2.6 27.2 TMEM159 promethin ENSG00000011638 "Transmembrane protein 159" Q96B96 16 21158377-21180616 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 128.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 121.2;Basal squamous epithelial cells: 176.4;Squamous epithelial cells: 127.5;Suprabasal keratinocytes: 150.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 67.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018033, HPA063509" Approved Approved Vesicles NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" Vesicles "HPA018033: AB_2204762, HPA063509: AB_2685026" "unprognostic (7.62e-3)" "unprognostic (2.42e-1)" "unprognostic (1.99e-2)" "unprognostic (1.06e-1)" "unprognostic (8.68e-2)" "unprognostic (6.80e-2)" "unprognostic (3.32e-1)" "unprognostic (2.93e-1)" "unprognostic (3.35e-1)" "unprognostic (2.93e-3)" "prognostic unfavorable (1.59e-4)" "unprognostic (2.03e-1)" "prognostic favorable (8.11e-5)" "unprognostic (8.28e-2)" "unprognostic (1.28e-1)" "unprognostic (1.84e-2)" "unprognostic (1.57e-2)" 40.2 33.0 3.8 5.4 8.0 3.2 27.0 6.0 4.0 47.4 2.3 42.6 4.3 28.6 7.9 61.9 26.3 20.1 91.6 3.4 3.3 16.5 2.5 19.9 11.7 2.7 3.3 40.8 12.4 14.1 3.2 4.0 3.9 22.1 12.0 5.7 36.8 10.4 128.5 96.0 17.9 17.8 2.4 7.1 21.1 10.5 5.4 5.0 15.4 100.6 16.7 47.9 57.3 2.8 14.3 7.1 7.6 28.7 67.9 44.1 3.4 7.4 27.6 2.9 4.9 5.6 21.4 20.2 7.9 21.6 12.9 23.1 11.7 13.0 3.4 7.7 4.5 9.1 1.9 11.1 15.4 7.2 24.2 17.3 58.8 15.4 48.1 12.2 15.0 10.8 6.9 6.1 5.8 25.2 5.6 6.7 7.0 14.1 3.5 28.9 4.2 7.3 38.1 41.1 1.2 1.1 18.2 25.8 9.8 13.5 46.0 6.5 10.6 5.4 5.4 25.6 1.9 0.5 1.7 7.2 22.2 6.4 5.3 19.5 8.8 7.0 9.7 6.9 9.8 12.2 12.7 8.2 5.4 9.6 9.9 9.6 3.9 7.3 10.3 14.3 14.8 6.6 3.8 8.0 6.0 4.0 3.4 3.3 2.7 3.3 3.9 2.4 5.4 2.8 17.3 9.6 20.9 0.0 12.9 121.2 38.5 31.9 176.4 1.0 53.3 55.2 59.4 15.7 31.8 22.0 0.0 4.8 9.1 34.5 7.9 19.7 0.8 11.4 12.8 13.7 14.5 11.8 1.9 21.3 2.1 44.3 19.4 19.3 15.8 14.0 17.5 0.2 10.2 1.7 0.8 30.6 12.2 15.7 39.0 2.2 67.4 13.8 30.2 4.7 22.7 44.7 7.2 1.0 0.1 24.7 41.8 37.2 3.8 45.3 23.1 21.1 11.2 1.5 32.9 26.5 35.7 2.0 9.9 127.5 150.2 1.9 14.8 5.1 29.9 66.6 TMEM211 bA9F11.1 ENSG00000206069 "Transmembrane protein 211" Q6ICI0 22 24934954-24946695 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "cervix: 2.6;salivary gland: 5.8;stomach 1: 3.2" "Cell type enriched" "Detected in some" 19 "Ionocytes: 36.7" "Group enriched" "Detected in some" 5 "colorectal cancer: 4.8;endometrial cancer: 3.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA066784 Uncertain NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA066784: AB_2685722" "unprognostic (7.89e-3)" "unprognostic (1.19e-1)" "unprognostic (2.15e-1)" "unprognostic (1.09e-2)" "unprognostic (5.97e-3)" "unprognostic (5.88e-2)" "unprognostic (1.31e-3)" "unprognostic (3.26e-2)" "unprognostic (2.06e-1)" "unprognostic (6.42e-2)" "unprognostic (2.65e-2)" "unprognostic (8.61e-3)" "unprognostic (3.59e-1)" "unprognostic (4.43e-2)" 0.0 0.0 0.1 0.3 0.3 0.0 0.4 0.3 0.2 2.6 0.0 0.3 0.0 0.6 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 5.8 0.0 0.0 1.3 0.0 0.0 0.0 0.0 3.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.3 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.9 0.0 0.0 1.3 1.3 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 36.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 TMEM213 ENSG00000214128 "Transmembrane protein 213" A2RRL7 7 138797952-138838101 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 12 "kidney: 76.0;salivary gland: 52.3" "Cell type enhanced" "Detected in some" "Collecting duct cells: 53.3;Distal tubular cells: 144.8;Melanocytes: 26.6" "Cancer enriched" "Detected in some" 22 "renal cancer: 21.7" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 4 "basophil: 2.1;neutrophil: 1.1;NK-cell: 2.0" "Group enriched" "Detected in many" 5 "granulocytes: 2.1;NK-cells: 2.0" "Cell line enhanced" "Detected in single" "RPTEC TERT1: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA054059 Enhanced NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" "HPA054059: AB_2682361" "unprognostic (2.79e-2)" "unprognostic (2.56e-1)" "unprognostic (1.85e-2)" "unprognostic (1.19e-2)" "unprognostic (3.19e-2)" "unprognostic (6.84e-2)" "unprognostic (1.17e-2)" "unprognostic (2.10e-1)" "unprognostic (6.14e-2)" "unprognostic (6.08e-2)" "unprognostic (1.91e-2)" "prognostic favorable (5.54e-7)" "unprognostic (4.33e-1)" "unprognostic (9.99e-2)" "unprognostic (3.06e-1)" "unprognostic (1.05e-2)" 0.1 0.1 0.5 0.2 0.5 1.1 4.7 0.6 0.7 2.8 0.4 0.1 1.3 0.2 0.6 0.3 0.1 0.2 0.0 0.6 0.1 76.0 0.1 1.1 0.2 0.2 0.1 0.1 0.6 0.0 0.1 0.1 0.4 0.4 0.1 0.3 52.3 1.2 0.1 5.3 0.3 0.1 0.0 0.2 0.4 0.1 0.5 0.1 0.1 0.0 0.1 0.0 0.0 1.0 0.0 0.1 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.2 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.2 0.1 0.2 0.0 0.3 0.0 0.2 0.1 0.0 0.1 2.1 0.2 0.2 0.3 0.2 0.4 0.2 0.1 0.2 0.1 0.3 0.2 0.1 1.1 2.0 0.2 0.2 0.1 0.1 0.5 0.5 0.6 0.7 0.6 0.1 0.2 0.1 0.4 0.0 0.5 1.0 0.1 3.2 9.9 0.0 0.1 0.0 0.9 3.0 0.0 0.4 14.1 7.9 0.4 0.0 4.4 53.3 0.0 0.0 0.2 0.0 144.8 0.0 0.0 0.9 0.4 0.5 0.0 0.0 0.6 0.2 0.1 0.2 0.0 1.3 1.3 0.1 0.0 0.0 0.1 1.7 0.4 0.0 2.0 0.0 0.8 0.0 0.0 0.1 26.6 0.0 0.0 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.9 3.5 1.3 0.0 0.5 0.2 0.0 0.2 0.0 0.4 0.0 0.6 0.0 0.2 0.6 TMEM86A FLJ90119 ENSG00000151117 "Transmembrane protein 86A" Q8N2M4 11 18693122-18704785 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 17.6" "Cell type enhanced" "Detected in many" "Hofbauer cells: 40.6;Theca cells: 17.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 3.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 17.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057119 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Golgi apparatus" "HPA057119: AB_2683342" "unprognostic (1.25e-1)" "unprognostic (1.09e-3)" "unprognostic (8.08e-3)" "unprognostic (1.89e-1)" "unprognostic (2.53e-1)" "unprognostic (1.10e-1)" "unprognostic (4.05e-2)" "unprognostic (2.94e-1)" "unprognostic (3.73e-1)" "unprognostic (1.74e-1)" "unprognostic (8.14e-2)" "unprognostic (2.67e-1)" "unprognostic (2.36e-1)" "unprognostic (1.50e-2)" "unprognostic (7.92e-2)" "unprognostic (4.20e-1)" "unprognostic (3.24e-1)" 2.8 2.7 2.6 2.2 2.2 0.3 3.2 2.1 2.8 2.3 3.8 1.5 1.4 2.2 1.0 2.3 2.6 4.0 2.9 2.1 2.6 9.5 2.6 3.5 4.7 3.1 2.7 7.1 3.4 5.4 2.2 4.3 2.5 1.6 1.8 5.7 2.7 1.4 2.9 17.6 2.0 1.9 2.7 4.9 2.1 2.3 4.0 1.6 2.1 2.5 2.5 2.3 3.6 4.5 0.0 0.2 0.6 3.1 2.7 0.0 0.1 0.6 0.5 0.5 0.5 0.0 0.4 0.0 1.2 0.6 3.0 0.3 0.2 0.1 0.3 0.2 1.9 0.2 0.1 0.0 2.1 0.0 2.8 3.8 1.2 0.1 0.2 0.7 1.7 1.8 0.6 0.0 1.3 1.7 0.0 0.0 0.2 0.5 1.6 0.0 5.1 0.0 17.5 3.8 1.0 1.3 1.0 3.2 1.4 1.1 3.9 0.4 1.9 0.5 0.2 0.1 0.1 3.2 2.7 0.0 1.1 0.0 1.1 0.0 1.9 0.1 0.2 1.4 0.5 0.0 0.2 0.4 3.4 0.1 0.4 0.8 0.0 0.1 0.5 2.0 0.5 0.8 2.6 2.2 2.1 2.8 2.1 2.6 3.1 2.7 2.5 2.7 4.0 4.5 1.9 0.0 0.0 0.3 0.0 0.1 0.8 0.4 0.0 5.2 3.5 1.8 2.2 0.0 0.7 11.0 8.4 0.5 1.4 0.6 7.9 7.8 12.2 1.1 1.9 2.1 3.5 0.0 0.5 8.0 0.3 1.7 1.1 1.0 0.0 3.0 3.9 1.6 40.6 0.0 0.8 0.8 0.0 12.7 0.8 12.1 2.1 8.3 0.0 3.7 2.3 2.6 0.0 2.0 0.1 7.4 0.1 1.9 0.4 0.6 0.0 8.3 0.4 4.8 6.6 0.4 1.2 7.8 2.6 0.2 0.3 2.3 0.7 17.4 0.2 0.4 TMEM91 "DSPC3, FLJ27310, IFITMD6" ENSG00000142046 "Transmembrane protein 91" Q6ZNR0 19 41350911-41384083 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 212.0;Late spermatids: 451.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 193.3" "Group enriched" "Detected in all" 8 "granulocytes: 193.3;monocytes: 51.9" "Cell line enhanced" "Detected in many" "HEL: 20.1;HSkMC: 20.5;TIME: 19.8" "Low region specificity" "Detected in all" HPA053240 Uncertain NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 25: Spermatids - Spermatogenesis" "HPA053240: AB_2682085" "unprognostic (3.02e-3)" "unprognostic (1.92e-2)" "unprognostic (5.13e-3)" "unprognostic (2.97e-2)" "unprognostic (1.29e-1)" "unprognostic (9.90e-2)" "unprognostic (4.70e-2)" "unprognostic (2.83e-1)" "unprognostic (1.03e-1)" "unprognostic (5.69e-3)" "prognostic favorable (3.54e-5)" "unprognostic (1.07e-1)" "prognostic unfavorable (3.52e-7)" "unprognostic (1.14e-2)" "unprognostic (1.24e-1)" "unprognostic (1.63e-1)" "unprognostic (3.06e-2)" 24.0 12.8 32.3 6.9 43.1 36.2 19.7 19.5 35.2 39.1 27.7 26.6 3.5 18.6 10.2 22.6 30.2 8.2 16.4 29.3 49.0 20.3 9.6 23.3 6.5 29.2 33.3 20.1 17.7 4.1 26.2 9.4 28.4 23.0 3.9 9.2 11.4 8.6 5.4 66.3 14.3 8.7 23.3 37.5 12.3 37.8 52.7 5.7 20.5 7.3 7.6 29.8 31.3 24.2 3.3 7.0 5.4 2.7 6.4 13.6 5.0 2.6 3.4 1.3 2.1 0.5 2.9 1.5 2.4 3.0 2.1 0.9 1.3 2.4 3.0 2.3 3.6 20.1 5.7 11.1 12.3 3.4 5.2 20.5 12.6 4.0 9.8 14.8 9.2 3.7 3.8 6.2 2.1 6.3 2.5 6.6 2.3 0.9 4.2 4.2 1.2 1.4 3.4 1.6 1.4 3.3 5.0 1.0 4.1 3.8 1.3 9.9 19.8 3.1 3.0 2.9 2.7 3.8 0.6 1.1 6.5 4.6 1.2 36.8 51.9 4.0 5.9 12.3 7.4 0.7 3.4 3.1 9.5 1.4 8.0 3.9 193.3 1.5 9.1 14.6 4.7 41.2 32.3 43.1 19.5 35.2 29.3 49.0 29.2 33.3 28.4 23.3 52.7 24.2 20.2 3.2 22.4 23.8 3.5 17.8 22.9 59.8 7.4 8.3 10.7 15.9 5.3 2.8 25.0 7.3 6.2 2.7 10.6 0.7 1.9 5.3 212.0 12.0 12.1 13.7 14.4 4.8 11.7 3.2 84.3 21.7 1.1 4.8 34.2 13.0 20.0 3.8 15.7 8.4 18.9 1.6 10.2 67.6 8.4 451.5 14.0 51.6 8.8 7.5 30.7 4.1 20.6 5.0 5.8 3.8 18.5 7.2 1.7 6.5 2.3 2.5 13.5 6.4 6.6 4.8 8.6 4.9 9.0 9.7 21.3 8.6 7.8 3.7 1.7 10.4 TMEM97 MAC30 ENSG00000109084 "Transmembrane protein 97" Q5BJF2 17 28319200-28328685 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 113.4;pancreas: 322.0" "Cell type enhanced" "Detected in many" "Cholangiocytes: 121.5;Exocrine glandular cells: 196.4;Granulosa cells: 212.9;Hepatocytes: 226.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "CACO-2: 341.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044795, HPA076689" Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 39: CACO-2 - Unknown function" "Cluster 40: Granulosa cells - Unknown function" "Endoplasmic reticulum" "HPA044795: AB_10959306, HPA076689: " "unprognostic (1.35e-2)" "unprognostic (2.70e-1)" "unprognostic (1.39e-1)" "unprognostic (1.10e-3)" "unprognostic (1.81e-1)" "unprognostic (4.34e-2)" "unprognostic (3.20e-2)" "unprognostic (9.03e-2)" "unprognostic (1.04e-2)" "unprognostic (1.81e-1)" "unprognostic (1.11e-2)" "unprognostic (5.17e-2)" "prognostic unfavorable (1.24e-4)" "unprognostic (1.08e-1)" "unprognostic (2.26e-1)" "unprognostic (1.99e-1)" "unprognostic (4.01e-2)" 4.3 26.0 5.2 7.3 6.3 6.7 11.7 6.6 9.0 5.7 6.5 14.3 16.4 6.7 4.7 7.4 13.1 10.2 3.4 6.3 5.4 7.1 113.4 17.4 7.1 14.9 14.2 18.1 322.0 6.5 1.6 6.8 14.9 10.8 12.6 6.3 3.7 3.3 15.5 9.8 11.2 5.7 5.0 4.6 38.8 58.0 7.4 7.6 4.2 9.1 8.2 26.6 5.2 6.8 46.1 120.4 214.8 105.5 28.0 40.2 70.5 44.1 27.9 67.9 90.3 341.0 34.3 126.3 46.4 17.0 140.1 48.7 137.1 75.0 52.7 60.3 102.1 47.8 56.9 143.0 25.7 76.9 36.4 84.0 10.0 66.4 27.5 8.3 21.1 80.1 101.3 92.1 22.7 81.8 120.0 72.4 95.6 187.7 30.6 94.8 236.5 112.8 85.6 210.6 154.1 67.0 70.0 55.1 36.3 118.2 97.0 35.8 13.8 72.8 56.8 62.9 81.7 74.3 159.0 115.9 14.6 54.7 44.3 0.7 2.2 2.2 7.8 2.7 9.2 11.1 6.4 9.4 16.1 5.5 10.4 9.8 1.0 9.5 1.0 9.3 6.6 5.2 5.2 6.3 6.6 9.0 6.3 5.4 14.9 14.2 14.9 5.0 7.4 6.8 4.2 9.6 61.5 3.3 7.7 14.5 6.0 32.8 18.8 11.3 22.5 21.5 9.0 121.5 19.1 14.7 16.7 34.2 5.0 6.1 15.6 23.3 22.3 7.5 14.3 7.1 38.8 40.3 2.9 196.4 84.0 14.4 49.5 11.4 1.3 212.9 6.4 226.9 22.0 3.3 4.5 16.2 26.4 6.7 34.7 49.1 13.4 9.9 16.0 0.0 11.4 8.2 4.1 4.0 1.0 47.7 3.5 11.3 15.3 13.9 4.0 6.3 12.2 9.1 6.6 10.4 12.4 91.3 65.5 22.7 11.2 10.7 6.4 65.1 29.4 7.9 TMPRSS11F "FLJ16046, HATL4" ENSG00000198092 "Transmembrane serine protease 11F" Q6ZWK6 4 68053198-68129869 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "esophagus: 15.2;skin 1: 9.3;vagina: 4.8" "Cell type enriched" "Detected in some" 4 "Squamous epithelial cells: 6.9" "Group enriched" "Detected in some" 7 "cervical cancer: 1.6;head and neck cancer: 2.1;lung cancer: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "K-562: 1.6" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA026911 Uncertain NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA026911: AB_2205589" "unprognostic (9.46e-2)" "unprognostic (5.30e-1)" "unprognostic (7.16e-2)" "unprognostic (8.79e-3)" "unprognostic (1.09e-1)" "unprognostic (2.40e-1)" "unprognostic (1.22e-1)" "unprognostic (5.08e-2)" 0.0 0.0 0.1 0.0 0.1 0.0 1.1 0.0 0.3 2.2 0.0 0.0 0.0 0.0 0.0 15.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.2 0.5 0.1 0.0 0.1 1.0 0.0 0.1 9.3 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 4.1 0.0 4.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.1 0.3 0.1 0.5 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.4 6.9 0.0 0.3 0.0 0.1 0.0 0.5 TMPRSS13 "MSPL, MSPS, TMPRSS11" ENSG00000137747 "Transmembrane serine protease 13" Q9BYE2 11 117900641-117929459 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 15.7;skin 1: 41.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 15.9;Extravillous trophoblasts: 21.2;Glandular and luminal cells: 10.9;Ionocytes: 16.2;Syncytiotrophoblasts: 19.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 13.8;BEWO: 29.9;MCF7: 27.0;SK-BR-3: 42.8;T-47d: 43.5" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 6: T47d - Mammary gland" "Cluster 38: Extravillous trophoblasts - Unknown function" "unprognostic (1.08e-3)" "unprognostic (5.18e-2)" "unprognostic (6.59e-2)" "unprognostic (1.06e-3)" "unprognostic (1.04e-1)" "unprognostic (1.01e-1)" "unprognostic (3.64e-1)" "unprognostic (5.61e-2)" "unprognostic (1.20e-1)" "unprognostic (1.49e-1)" "unprognostic (1.92e-2)" "unprognostic (2.03e-1)" "unprognostic (3.16e-6)" "unprognostic (2.05e-1)" "unprognostic (7.75e-2)" "unprognostic (1.08e-1)" "unprognostic (3.44e-1)" 0.3 0.4 0.2 0.7 0.2 0.6 7.1 0.0 0.7 6.7 0.0 0.4 0.3 0.6 0.6 15.7 0.3 0.4 0.1 0.9 0.0 2.6 0.2 3.9 1.2 0.0 0.0 0.1 2.5 0.0 0.3 2.9 0.0 1.4 0.4 0.0 11.0 0.1 0.2 41.0 0.8 0.2 0.0 1.5 0.2 0.4 0.0 0.9 6.6 0.0 4.8 0.5 9.3 0.1 13.8 0.1 0.0 0.0 0.0 0.0 29.9 0.0 0.0 0.0 0.0 10.2 0.1 0.7 0.1 0.0 0.0 1.3 0.0 0.1 0.0 0.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.5 0.7 0.0 27.0 0.1 0.1 0.0 0.4 0.0 0.0 0.0 1.4 0.0 4.0 0.4 0.1 0.0 42.8 0.6 1.7 43.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.2 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.5 0.1 0.2 0.2 0.2 0.0 0.7 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 4.6 0.0 0.2 1.7 4.6 1.7 1.2 0.0 7.4 4.6 1.4 7.2 5.3 0.0 0.0 15.9 0.2 0.3 0.0 8.3 0.3 2.4 1.3 0.2 0.0 0.0 0.2 1.2 21.2 0.3 0.5 10.9 0.0 0.0 0.0 0.0 2.9 0.0 0.1 0.5 16.2 1.2 1.9 0.8 0.0 1.7 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.3 5.7 3.9 0.0 0.7 0.0 0.0 0.0 0.4 0.0 0.2 5.2 8.0 19.4 0.4 0.5 0.8 9.0 TMPRSS2 PRSS10 ENSG00000184012 "Transmembrane serine protease 2" O15393 21 41464300-41531116 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 280.4;stomach 1: 146.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 404.8;Gastric mucus-secreting cells: 155.4;Paneth cells: 368.3;Prostatic glandular cells: 203.4;Proximal enterocytes: 159.6;Urothelial cells: 166.6" "Cancer enriched" "Detected in many" 7 "prostate cancer: 250.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 22.8;MCF7: 10.5;OE19: 35.9;RT4: 57.8;SK-BR-3: 11.7" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA034493, HPA035787" Enhanced Supported "Plasma membrane" "Secreted in other tissues" NA NA "Cluster 4: Stomach - Digestion" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "HPA034493: , HPA035787: AB_2674782" "unprognostic (4.80e-3)" "unprognostic (3.49e-1)" "unprognostic (2.16e-1)" "prognostic favorable (2.56e-4)" "unprognostic (1.72e-1)" "unprognostic (1.05e-2)" "unprognostic (4.28e-2)" "unprognostic (1.51e-3)" "unprognostic (9.43e-2)" "unprognostic (9.02e-3)" "unprognostic (6.24e-2)" "unprognostic (6.43e-2)" "prognostic favorable (7.86e-6)" "unprognostic (2.00e-2)" "unprognostic (1.68e-1)" "unprognostic (1.41e-1)" "unprognostic (2.15e-2)" 0.6 0.2 0.4 13.9 0.4 0.1 20.1 0.2 0.4 5.0 3.1 104.0 78.5 1.0 2.8 36.1 10.7 24.1 0.2 0.3 0.3 47.7 33.5 39.9 0.2 0.4 0.3 0.2 111.4 4.0 1.5 0.2 0.3 280.4 78.0 0.2 76.2 7.7 0.1 7.3 89.6 3.3 0.1 0.2 146.2 1.5 0.3 0.8 19.2 0.1 10.2 35.7 7.6 0.5 0.1 0.0 0.1 0.0 0.1 0.1 2.3 0.0 0.0 0.1 0.1 22.8 3.3 0.1 0.4 0.1 0.1 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.1 3.7 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.1 0.1 0.0 10.5 0.3 1.0 2.3 35.9 0.2 0.1 0.0 2.6 1.3 57.8 0.2 0.7 0.3 11.7 0.3 0.4 8.8 0.0 0.0 0.1 0.6 0.6 0.1 0.0 0.2 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.2 0.4 0.3 0.3 0.4 0.3 0.3 0.1 0.3 0.5 0.1 51.3 109.8 0.0 1.7 0.3 30.9 6.8 0.0 0.0 34.0 25.8 0.6 32.9 42.1 47.8 0.0 0.7 1.1 404.8 23.5 39.2 21.3 7.4 0.5 1.3 18.0 2.7 0.2 60.4 0.1 1.0 155.4 5.8 7.0 0.0 0.4 32.0 0.1 0.0 0.1 84.1 44.7 0.3 0.3 4.8 0.0 2.0 10.6 0.0 0.6 0.0 0.0 0.0 0.0 65.1 368.3 0.0 0.0 203.4 159.6 3.8 36.6 0.0 0.0 1.6 2.0 0.4 1.4 2.1 0.1 0.3 1.1 0.0 105.7 166.6 TOM1L2 ENSG00000175662 "Target of myb1 like 2 membrane trafficking protein" Q6ZVM7 17 17843511-17972422 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 180.5;Cone photoreceptor cells: 158.4;Oligodendrocytes: 123.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HaCaT: 104.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022541, HPA023304" Enhanced Approved "Golgi apparatus,Intermediate filaments" NA NA 73000 "Cluster 6: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 9: Photoreceptor cells - Phototransduction" "Intermediate filaments" "Golgi apparatus" "HPA022541: AB_1858182, HPA023304: AB_1858183" "unprognostic (2.32e-1)" "unprognostic (7.54e-2)" "unprognostic (1.12e-1)" "unprognostic (2.57e-2)" "unprognostic (3.25e-2)" "prognostic favorable (1.24e-4)" "unprognostic (2.22e-1)" "unprognostic (1.08e-1)" "unprognostic (6.29e-2)" "prognostic unfavorable (2.58e-4)" "prognostic favorable (1.92e-4)" "unprognostic (3.19e-2)" "prognostic favorable (6.21e-9)" "unprognostic (7.11e-2)" "unprognostic (1.40e-1)" "unprognostic (4.18e-2)" "unprognostic (4.51e-2)" 20.7 30.5 64.0 9.5 62.7 6.1 20.3 52.7 70.0 31.9 21.3 44.2 14.0 33.2 11.0 64.4 26.6 13.0 141.0 66.0 56.4 31.3 13.9 23.2 7.7 91.5 80.3 32.9 19.7 40.3 42.2 9.0 95.3 37.3 13.8 50.2 21.3 28.7 67.1 59.7 20.9 23.3 49.7 16.6 34.9 39.4 74.6 8.8 48.5 55.4 12.9 31.4 35.1 72.7 27.1 29.0 8.2 6.2 19.1 19.3 14.2 43.3 20.1 22.9 19.3 28.2 17.6 5.0 52.9 40.8 13.3 104.3 6.8 24.1 14.0 7.2 12.7 8.0 28.0 6.0 12.2 2.0 5.2 22.9 16.6 20.5 15.2 19.6 23.3 7.3 3.0 6.9 30.3 27.1 3.6 4.6 1.5 34.4 19.5 4.7 20.7 12.0 32.4 48.1 8.7 8.4 19.5 25.2 15.3 55.9 13.4 3.6 31.8 21.9 6.5 46.0 16.8 6.1 5.1 2.3 26.4 2.7 55.2 10.0 3.3 4.8 2.8 1.0 2.0 1.6 2.6 2.4 1.6 2.2 4.3 3.2 12.8 1.4 3.3 1.9 1.3 1.7 64.0 62.7 52.7 70.0 66.0 56.4 91.5 80.3 95.3 49.7 74.6 72.7 10.1 32.1 17.0 180.5 9.5 10.8 14.6 13.9 7.4 74.5 20.9 14.1 73.7 15.7 16.6 11.0 158.4 8.5 10.2 43.3 5.9 12.2 30.8 14.1 9.4 12.4 20.4 4.8 63.2 8.7 17.4 12.7 13.3 15.7 2.5 28.1 16.4 13.4 9.2 95.9 74.2 19.2 18.3 8.5 7.6 64.2 26.4 6.4 12.4 35.6 11.8 28.1 10.3 66.9 123.2 16.1 41.0 25.6 8.4 39.1 22.4 11.1 22.9 78.3 19.7 18.0 13.0 16.7 12.1 37.2 17.2 32.2 10.0 30.8 15.4 64.5 TOP2A TOP2 ENSG00000131747 "DNA topoisomerase II alpha" P11388 17 40388525-40417896 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Biological rhythms" "DNA-binding, Isomerase, Topoisomerase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 127.8;testis: 65.7" "Cell type enhanced" "Detected in many" "Erythroid cells: 216.8;Granulosa cells: 117.5;Spermatocytes: 621.2;Spermatogonia: 269.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "T-reg: 2.4" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basal ganglia: 4.2;white matter: 8.0" "Low region specificity" "Detected in some" "CAB002448, HPA006458, HPA026773" Enhanced Approved Supported Nucleoplasm,Nucleoli Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Nucleoli "CAB002448: AB_564035, HPA006458: AB_1858189, HPA026773: AB_1858190" "unprognostic (2.09e-1)" "unprognostic (1.24e-1)" "unprognostic (2.28e-3)" "unprognostic (9.42e-3)" "unprognostic (1.80e-1)" "unprognostic (1.52e-1)" "prognostic unfavorable (5.92e-6)" "prognostic unfavorable (4.99e-4)" "unprognostic (6.21e-3)" "unprognostic (2.09e-1)" "prognostic unfavorable (3.83e-5)" "unprognostic (5.03e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (7.46e-2)" "unprognostic (1.07e-1)" "unprognostic (2.18e-1)" "unprognostic (2.29e-1)" 2.2 2.5 0.2 20.0 0.2 42.0 5.4 0.1 0.7 5.0 1.1 17.8 18.1 3.9 0.3 29.0 1.5 2.6 1.2 0.2 0.2 1.2 2.8 4.1 40.3 0.2 0.8 1.0 0.9 0.3 0.3 15.9 0.5 1.4 19.8 0.1 4.3 0.5 0.3 15.3 17.0 7.6 0.2 9.9 8.9 65.7 1.1 127.8 1.9 0.2 42.5 6.0 9.6 0.4 212.6 275.6 343.1 158.0 16.8 33.9 76.3 283.3 151.5 255.0 224.2 130.5 157.6 339.4 140.1 96.7 152.7 326.5 266.8 113.5 339.5 182.7 177.8 224.8 167.9 216.7 1.6 318.4 228.6 7.4 9.2 179.8 181.4 55.1 136.3 216.5 247.5 225.8 279.2 72.6 372.3 209.6 143.0 152.4 108.3 310.7 531.9 141.3 61.6 133.3 201.6 144.6 229.3 281.4 89.4 198.2 236.9 143.2 90.3 167.0 233.2 195.5 276.7 128.4 154.9 290.7 94.3 214.9 285.0 0.2 0.0 0.0 0.2 0.0 0.0 0.6 0.3 0.3 0.1 0.1 0.0 0.0 0.1 1.4 0.1 0.0 2.4 0.4 0.2 0.2 0.1 0.7 0.2 0.2 0.2 0.8 0.5 0.2 1.1 0.4 1.0 0.0 2.0 0.3 17.4 11.7 3.7 15.0 2.2 0.0 18.7 17.1 1.3 2.8 5.8 0.0 0.0 72.9 6.1 19.8 0.0 0.8 20.3 12.7 15.8 9.3 0.0 216.8 0.2 0.0 92.4 23.3 23.0 10.0 0.0 117.5 20.7 5.4 83.5 0.0 0.1 34.2 18.3 33.9 13.2 19.1 4.7 14.1 1.8 0.0 2.6 0.0 3.1 0.0 0.1 0.3 3.5 1.9 31.3 3.1 3.4 0.1 1.8 0.0 72.3 0.5 19.5 621.2 269.6 45.1 6.1 8.9 14.8 4.3 61.0 6.9 TP63 "EEC3, KET, NBP, OFC8, p51, p53CP, p63, p73H, p73L, SHFM4, TP53CP, TP53L, TP73L" ENSG00000073282 "Tumor protein p63" Q9H3D4 3 189631389-189897276 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Apoptosis, Notch signaling pathway, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 69.6;skin 1: 137.3" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 275.4;Basal squamous epithelial cells: 335.2;Squamous epithelial cells: 173.4;Suprabasal keratinocytes: 283.1" "Group enriched" "Detected in many" 11 "cervical cancer: 37.9;head and neck cancer: 73.3;lung cancer: 37.3;urothelial cancer: 21.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HaCaT: 87.1;HBEC3-KT: 167.3;hTCEpi: 124.0;hTERT-HME1: 117.3;RT4: 185.1" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB000083, HPA006288, HPA006289, HPA007009, HPA007010" Enhanced Enhanced Nucleoplasm NA NA "Cluster 17: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 15: RT4 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "CAB000083: AB_2207187, HPA006288: AB_1080334, HPA006289: , HPA007009: , HPA007010: AB_1080336" "prognostic favorable (1.07e-4)" "unprognostic (1.30e-1)" "unprognostic (1.44e-1)" "unprognostic (3.02e-1)" "unprognostic (4.38e-2)" "unprognostic (3.50e-1)" "unprognostic (1.29e-1)" "unprognostic (5.17e-2)" "unprognostic (2.78e-1)" "unprognostic (5.37e-2)" "unprognostic (2.09e-3)" "unprognostic (1.54e-1)" "unprognostic (1.87e-5)" "unprognostic (1.86e-1)" "unprognostic (1.05e-1)" "unprognostic (1.62e-1)" "unprognostic (2.74e-3)" 0.5 0.3 0.3 0.6 0.3 0.4 18.0 0.9 0.5 23.5 0.3 0.3 0.1 0.3 10.5 69.6 1.0 0.3 0.6 0.5 0.5 0.3 0.4 1.9 1.0 0.4 0.6 0.1 0.3 0.0 0.5 10.8 0.7 17.4 0.2 0.0 20.8 18.0 42.4 137.3 0.2 0.3 0.2 0.2 0.4 3.4 0.4 23.1 0.3 12.4 17.7 18.6 54.4 0.4 2.3 4.6 0.0 0.1 0.2 0.1 1.2 0.1 0.0 0.0 0.0 0.0 0.0 16.6 0.6 0.1 0.2 87.1 0.0 167.3 0.0 1.4 0.0 1.9 1.3 0.4 0.0 0.0 0.3 0.2 124.0 0.2 117.3 0.1 0.0 0.0 0.0 0.1 0.1 0.4 0.1 0.2 0.3 0.2 0.0 1.0 0.3 0.0 0.2 185.1 0.2 0.1 0.2 0.0 0.0 2.5 0.9 0.2 0.3 0.2 0.1 0.2 0.0 25.3 0.3 1.1 0.5 0.1 0.8 0.6 0.0 0.2 0.1 0.0 0.0 0.7 0.2 0.1 0.0 0.3 0.1 0.1 0.4 0.2 0.0 0.2 0.1 0.0 0.3 0.3 0.9 0.5 0.5 0.5 0.4 0.6 0.7 0.2 0.4 0.4 0.2 0.0 5.3 1.0 0.9 275.4 26.8 61.9 335.2 0.0 0.9 30.1 0.7 0.0 8.5 0.0 0.0 24.9 0.1 0.1 0.0 0.2 1.8 0.0 0.1 1.1 0.0 0.0 1.3 0.2 2.8 1.4 0.0 0.1 0.0 0.0 0.0 0.1 2.4 0.0 4.8 0.0 2.0 0.0 11.9 0.4 0.3 0.7 8.8 14.0 0.6 0.0 0.0 0.5 1.4 1.6 0.0 1.2 1.6 5.6 0.0 0.0 2.8 0.0 0.0 5.3 0.9 0.5 2.4 173.4 283.1 8.9 0.6 0.2 0.0 15.2 TPRN "C9orf75, DFNB79, FLJ90254" ENSG00000176058 Taperin Q4KMQ1 9 137191617-137204193 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Hearing "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 56.4;pancreas: 91.4" "Cell type enhanced" "Detected in all" "Distal enterocytes: 177.7;Proximal enterocytes: 95.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "MCF7: 61.9" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 23.6" "HPA020899, HPA076667" Approved Approved "Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 22: Non-specific - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "HPA020899: AB_1845835, HPA076667: " "unprognostic (5.41e-2)" "prognostic favorable (2.13e-4)" "unprognostic (2.94e-1)" "unprognostic (9.28e-2)" "unprognostic (1.68e-1)" "unprognostic (2.61e-2)" "unprognostic (3.59e-3)" "unprognostic (8.20e-2)" "unprognostic (9.96e-2)" "unprognostic (1.21e-1)" "unprognostic (1.89e-2)" "unprognostic (4.77e-2)" "prognostic favorable (5.16e-9)" "unprognostic (1.96e-3)" "unprognostic (6.35e-2)" "unprognostic (1.51e-1)" "unprognostic (5.44e-2)" 3.7 5.1 24.3 4.4 37.8 2.7 4.8 29.9 33.1 5.2 15.1 25.4 22.0 4.7 0.9 20.5 5.1 3.2 10.7 23.5 23.7 19.1 24.3 8.1 2.4 33.1 32.4 6.4 91.4 2.5 6.0 3.3 28.2 8.0 6.9 1.7 11.8 3.4 6.2 15.6 26.0 1.5 20.8 5.0 29.3 9.3 31.9 2.0 5.5 3.1 1.5 7.8 6.9 56.4 10.2 11.4 3.8 17.0 5.2 5.5 30.1 7.0 4.3 7.0 3.9 38.5 12.1 18.6 10.1 3.6 9.2 30.4 7.9 3.9 0.9 11.9 11.1 8.7 17.5 25.5 7.9 13.5 10.8 4.7 7.5 6.2 4.3 4.6 4.5 8.2 16.1 6.4 2.1 61.9 8.9 29.0 13.5 55.5 14.8 26.3 9.1 28.4 15.9 21.0 24.4 8.9 10.8 49.6 13.0 2.9 57.8 21.0 5.0 12.7 6.0 20.1 15.1 5.3 11.0 9.7 9.1 12.1 7.2 0.0 0.8 0.0 0.3 0.8 0.1 0.3 0.3 0.5 0.6 0.3 0.1 0.3 0.0 0.8 0.4 0.6 0.6 0.2 24.3 37.8 29.9 33.1 23.5 23.7 33.1 32.4 28.2 20.8 31.9 56.4 4.6 19.2 5.5 6.2 3.5 1.8 1.3 2.6 2.2 19.3 13.2 9.5 7.6 15.7 2.6 16.5 6.2 5.4 8.4 177.7 7.9 8.0 3.1 7.6 4.1 2.9 9.0 7.4 3.3 45.4 1.3 3.0 15.3 9.6 1.3 8.7 3.9 19.5 3.6 11.8 3.8 46.0 6.1 2.8 1.6 5.3 3.4 5.2 5.4 1.0 2.8 12.4 1.0 2.5 30.4 15.3 39.7 4.5 1.9 3.3 95.9 20.0 2.3 7.3 6.6 3.2 4.5 2.7 4.4 5.8 2.8 1.9 4.5 10.3 36.7 1.7 TRARG1 "BEC-1, DSPB1, IFITMD3, LOST1, TUSC5" ENSG00000184811 "Trafficking regulator of GLUT4 (SLC2A4) 1" Q8IXB3 17 1279662-1300978 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 34 "adipose tissue: 101.4;breast: 68.7" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 2.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 294 "ASC diff: 29.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA050825 Approved NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA050825: AB_2681252" "unprognostic (5.84e-2)" "unprognostic (7.21e-2)" "unprognostic (1.15e-1)" "unprognostic (3.00e-1)" "unprognostic (2.01e-1)" "unprognostic (2.91e-2)" "unprognostic (1.09e-2)" "unprognostic (1.01e-1)" "unprognostic (2.73e-1)" "unprognostic (1.83e-2)" "unprognostic (2.66e-1)" "unprognostic (5.79e-2)" "unprognostic (1.90e-3)" "unprognostic (6.26e-2)" "unprognostic (3.12e-1)" "unprognostic (5.10e-1)" 101.4 1.1 0.0 1.2 0.0 0.0 68.7 0.0 0.4 0.4 0.0 1.2 0.0 0.2 0.0 0.1 0.1 0.6 1.7 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.4 0.0 1.2 2.1 2.3 0.0 0.0 0.0 0.6 0.6 0.0 0.1 1.0 0.6 0.0 1.5 0.3 0.0 0.0 0.0 0.0 0.0 29.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TREX2 ENSG00000183479 "Three prime repair exonuclease 2" Q9BQ50 X 153444720-153470587 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 24.5" "Cell type enhanced" "Detected in single" "Suprabasal keratinocytes: 1.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 11 "basophil: 1.7;eosinophil: 2.7" "Lineage enriched" "Detected in single" 14 "granulocytes: 2.7" "Cell line enhanced" "Detected in many" "HEK 293: 5.4;U-698: 7.3;U-937: 7.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA054060 Uncertain NA NA "Cluster 10: Basophils - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 47: Cytotrophoblasts - Unknown function" "HPA054060: AB_2682362" "unprognostic (2.32e-2)" "unprognostic (2.05e-3)" "unprognostic (1.13e-3)" "unprognostic (7.18e-4)" "unprognostic (6.05e-2)" "unprognostic (1.81e-2)" "unprognostic (8.40e-2)" "unprognostic (2.19e-1)" "unprognostic (2.09e-1)" "unprognostic (1.61e-1)" "unprognostic (1.70e-1)" "unprognostic (1.57e-1)" "unprognostic (1.42e-1)" "unprognostic (1.52e-1)" "unprognostic (9.34e-2)" "unprognostic (2.15e-1)" "unprognostic (1.23e-2)" 0.9 0.5 0.4 0.6 0.4 0.7 0.8 0.5 1.1 3.2 5.0 0.6 0.2 1.2 0.6 2.9 1.2 0.7 1.0 0.7 0.2 1.4 0.6 1.1 1.4 0.5 0.3 0.9 0.8 0.2 0.7 0.9 0.5 1.3 0.2 0.0 1.9 2.4 0.3 24.5 1.1 0.5 0.3 2.4 0.7 1.0 0.4 0.5 1.3 0.1 1.1 0.6 3.2 0.4 2.1 2.6 0.2 0.9 0.3 0.5 0.2 0.6 0.5 0.5 1.4 0.7 0.5 0.2 1.3 0.5 0.1 2.2 0.9 1.4 0.0 2.3 5.4 0.2 0.5 0.3 0.2 0.6 1.4 0.6 1.3 0.6 0.5 0.3 0.2 0.4 0.3 2.5 0.1 2.5 1.5 1.6 0.8 0.4 1.7 3.5 0.7 1.7 0.2 0.7 0.6 0.3 0.2 0.2 0.8 0.0 0.4 0.7 0.0 0.9 1.6 2.0 0.8 2.8 2.1 7.3 0.2 7.0 1.1 1.7 0.0 2.7 0.1 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.4 0.5 1.1 0.7 0.2 0.5 0.3 0.5 0.3 0.4 0.4 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 1.1 0.7 0.1 0.1 0.0 0.1 TRIB3 "C20orf97, dJ1103G7.3, TRB3" ENSG00000101255 "Tribbles pseudokinase 3" Q96RU7 20 362835-397559 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Stress response, Transcription, Transcription regulation" "Protein kinase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 80.5" "Cell type enhanced" "Detected in many" "Ductal cells: 53.1;Hepatocytes: 38.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 630.3;hTCEpi: 401.9;hTERT-HME1: 461.8;SK-MEL-30: 615.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA015272, HPA055442" Approved Supported Nucleoplasm NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 18: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 1: Pancreatic cells - Digestion" Nucleoplasm "HPA015272: AB_1858269, HPA055442: AB_2682818" "unprognostic (5.40e-2)" "unprognostic (1.89e-1)" "unprognostic (1.57e-1)" "unprognostic (2.25e-3)" "unprognostic (1.92e-1)" "prognostic unfavorable (1.70e-4)" "prognostic unfavorable (6.75e-5)" "unprognostic (1.52e-3)" "unprognostic (1.76e-1)" "unprognostic (1.24e-1)" "unprognostic (7.95e-2)" "unprognostic (1.79e-1)" "prognostic unfavorable (2.07e-13)" "unprognostic (7.62e-2)" "unprognostic (2.79e-2)" "unprognostic (2.31e-1)" "unprognostic (4.05e-3)" 8.0 16.4 5.6 4.0 5.4 16.1 7.8 6.0 6.7 4.4 6.5 4.4 1.3 2.9 3.0 20.5 2.2 2.6 4.0 5.1 6.5 9.9 80.5 15.4 6.5 5.5 5.5 3.2 17.3 13.3 15.2 8.4 5.6 7.8 2.2 2.7 10.4 3.0 1.8 13.6 5.3 1.8 4.4 12.1 10.2 1.4 6.7 5.6 38.2 0.5 5.9 4.8 5.3 4.4 80.9 41.6 5.1 11.9 13.7 17.9 33.7 23.9 65.8 23.0 47.5 86.7 40.0 35.3 22.2 22.5 102.3 62.6 22.6 107.7 21.4 12.4 16.2 27.5 8.9 144.2 630.3 71.5 12.7 73.3 401.9 43.5 461.8 16.2 45.1 86.1 97.3 155.2 2.3 77.3 4.2 87.0 11.8 122.8 133.0 15.2 7.1 77.1 27.0 33.3 14.7 23.0 5.6 192.2 615.5 7.2 55.7 185.6 24.6 11.7 20.6 0.3 36.2 52.3 73.9 63.5 10.5 61.4 43.6 5.1 6.4 1.4 13.2 4.9 9.4 21.0 12.3 15.3 6.7 13.8 13.7 9.8 4.4 10.2 2.6 2.8 9.7 7.8 5.6 5.4 6.0 6.7 5.1 6.5 5.5 5.5 5.6 4.4 6.7 4.4 7.9 3.2 1.5 0.3 9.3 6.8 10.9 20.3 3.4 6.8 12.7 8.3 1.6 11.5 8.5 1.8 4.2 14.1 4.0 3.4 0.0 53.1 0.0 0.2 1.6 15.8 1.2 5.7 2.2 22.7 6.4 3.9 0.0 2.6 5.1 0.5 6.8 38.4 6.4 0.0 3.1 8.8 6.1 3.3 4.4 0.0 1.8 3.0 7.2 0.0 4.2 1.0 14.4 1.0 0.6 24.0 1.9 1.5 10.0 12.2 0.0 0.1 2.9 7.0 6.6 6.5 6.9 2.4 3.1 4.0 5.4 7.1 5.7 3.5 2.2 6.7 TRIM29 "ATDC, FLJ36085" ENSG00000137699 "Tripartite motif containing 29" Q14134 11 120111286-120185529 "Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 600.1;skin 1: 551.2;vagina: 269.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 272.0;Basal squamous epithelial cells: 250.4;Late spermatids: 150.3;Squamous epithelial cells: 552.9;Suprabasal keratinocytes: 460.6;Urothelial cells: 159.3" "Cancer enhanced" "Detected in many" "head and neck cancer: 93.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 399.9;HBEC3-KT: 107.5;hTCEpi: 476.0;RT4: 190.5;SiHa: 268.3" "Not detected" "Not detected" "Region enriched" "Detected in single" 9 "spinal cord: 4.0" "HPA020053, HPA074841" Enhanced Approved "Nucleoplasm,Intermediate filaments,Cytosol" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments" "Nucleoplasm, Cytosol" "HPA020053: AB_1858280, HPA074841: " "unprognostic (1.10e-1)" "unprognostic (6.22e-2)" "unprognostic (1.53e-1)" "prognostic unfavorable (2.88e-4)" "unprognostic (9.79e-3)" "unprognostic (3.08e-2)" "unprognostic (3.30e-1)" "unprognostic (5.24e-3)" "unprognostic (1.37e-1)" "unprognostic (1.16e-1)" "prognostic unfavorable (4.46e-4)" "unprognostic (9.37e-2)" "unprognostic (4.29e-3)" "prognostic favorable (4.93e-4)" "unprognostic (2.59e-1)" "unprognostic (2.91e-2)" "unprognostic (4.15e-2)" 2.5 1.0 0.1 0.4 0.2 0.4 41.7 0.0 0.4 133.8 1.6 3.0 1.7 2.6 4.8 600.1 17.4 3.5 0.4 0.3 0.0 1.7 1.8 3.7 0.0 1.8 0.6 0.4 1.0 0.0 8.1 30.7 1.8 31.4 2.6 0.3 131.5 23.7 2.2 551.2 1.0 1.5 2.6 0.3 1.4 2.7 0.0 19.9 0.4 0.2 107.2 55.8 269.1 0.6 34.4 2.5 0.0 0.0 0.0 0.0 0.9 0.1 0.8 0.2 0.1 0.8 25.6 0.2 3.9 0.2 0.5 399.9 0.0 107.5 0.0 0.1 0.0 0.2 25.4 0.4 0.0 0.2 0.5 0.0 476.0 0.0 2.6 0.0 0.0 0.0 0.2 0.7 0.0 4.4 0.0 0.0 0.1 11.4 0.1 0.0 0.3 0.0 0.3 190.5 1.3 5.9 268.3 35.2 0.1 0.2 1.9 0.0 0.4 0.1 2.1 0.2 0.1 0.2 0.3 0.2 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.4 0.3 0.0 1.8 0.6 1.8 2.6 0.0 0.6 0.5 0.0 1.5 3.3 0.2 272.0 106.1 76.4 250.4 0.0 9.5 58.8 1.2 1.5 39.2 0.0 0.0 41.0 0.2 11.3 0.0 5.0 28.1 8.7 0.8 3.4 2.4 0.0 0.5 4.3 7.1 5.6 1.1 3.6 1.3 0.0 0.0 0.4 5.0 0.0 0.1 2.1 12.2 0.0 30.3 150.3 0.6 1.4 23.2 1.0 0.0 0.0 0.0 0.0 0.1 57.1 11.3 0.0 0.0 66.0 0.2 0.6 64.6 0.0 0.0 0.1 4.9 0.8 2.6 552.9 460.6 24.8 2.4 0.1 3.7 159.3 TRIM55 "MURF-2, RNF29" ENSG00000147573 "Tripartite motif containing 55" Q9BYV6 8 66126896-66175485 "Predicted intracellular proteins, Predicted membrane proteins" "Muscle protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "heart muscle: 61.8;liver: 37.9;skeletal muscle: 29.6;tongue: 33.7" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 108.9;Endometrial ciliated cells: 64.7;Hepatocytes: 30.4;Skeletal myocytes: 31.0;Spermatocytes: 23.8" "Group enriched" "Detected in some" 10 "liver cancer: 12.3;renal cancer: 5.8" "Region enhanced" "Detected in single" "cerebellum: 1.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "LHCN-M2: 426.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA038793, HPA053691" Approved Approved "Golgi apparatus,Cytosol" NA NA "Cluster 39: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "Golgi apparatus" Cytosol "HPA038793: AB_10673289, HPA053691: AB_2682231" "unprognostic (5.44e-3)" "unprognostic (1.25e-2)" "unprognostic (5.93e-3)" "unprognostic (4.07e-2)" "unprognostic (6.83e-3)" "unprognostic (3.77e-3)" "unprognostic (8.31e-2)" "unprognostic (2.46e-1)" "unprognostic (1.34e-1)" "unprognostic (1.38e-1)" "unprognostic (1.50e-1)" "unprognostic (5.18e-2)" "unprognostic (2.10e-2)" "unprognostic (9.51e-2)" "unprognostic (1.16e-2)" "unprognostic (1.77e-3)" 1.4 0.0 0.1 0.1 0.0 0.0 0.2 1.5 0.1 0.3 0.0 0.0 0.1 0.1 3.5 0.8 5.3 0.1 61.8 0.0 0.0 4.8 37.9 0.2 0.0 0.1 0.6 0.0 0.2 0.2 0.4 0.0 0.3 0.7 0.1 0.0 1.3 0.2 29.6 0.4 0.1 0.1 0.0 0.1 0.0 7.3 0.0 0.2 0.3 33.7 0.4 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.4 0.0 7.2 0.1 0.3 0.1 0.0 0.4 0.5 0.6 0.0 60.5 0.0 0.0 0.0 0.1 2.8 0.0 0.0 0.0 0.1 0.0 0.1 0.0 1.8 0.1 0.0 0.0 0.1 0.0 0.0 0.0 4.2 426.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 18.7 1.5 27.6 0.0 2.4 0.0 0.0 0.1 0.0 91.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 1.5 0.1 0.0 0.0 0.1 0.6 0.3 0.0 0.0 0.1 0.1 0.0 2.0 0.0 0.6 0.0 0.1 2.8 0.0 0.0 0.1 0.0 108.9 0.0 1.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 11.8 64.7 0.2 1.2 0.0 0.0 0.2 0.0 0.1 3.8 0.0 3.5 0.0 0.0 0.7 30.4 0.1 0.0 1.5 0.0 0.0 1.3 0.0 6.4 0.9 0.3 0.0 0.0 0.0 0.0 0.0 1.0 0.3 0.0 0.0 0.4 0.2 0.0 0.0 7.4 15.4 0.0 6.6 31.0 2.9 23.8 1.2 0.0 0.0 3.8 0.3 0.0 0.0 0.3 TROAP TASTIN ENSG00000135451 "Trophinin associated protein" Q12815 12 49323236-49331731 "Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 51.0;lymphoid tissue: 36.7;testis: 29.1" "Cell type enhanced" "Detected in many" "Early spermatids: 71.5;Erythroid cells: 75.6;Late spermatids: 70.2;Spermatocytes: 29.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 8.6" "Lineage enriched" "Detected in many" 4 "T-cells: 8.6" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA044102 Uncertain NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 21: OE19 - Mitochondria" "Cluster 12: Non-specific - Cell cycle regulation" "HPA044102: AB_10963691" "unprognostic (1.47e-1)" "unprognostic (2.76e-2)" "unprognostic (1.09e-1)" "unprognostic (3.92e-3)" "unprognostic (1.97e-1)" "unprognostic (4.29e-2)" "prognostic unfavorable (1.39e-5)" "unprognostic (3.43e-3)" "unprognostic (2.88e-2)" "unprognostic (2.65e-3)" "unprognostic (1.08e-3)" "unprognostic (3.51e-2)" "unprognostic (0.00e+0)" "unprognostic (1.80e-1)" "unprognostic (1.54e-1)" "unprognostic (1.92e-1)" "unprognostic (5.17e-2)" 1.3 1.5 0.2 7.3 0.3 51.0 1.4 0.2 0.7 2.8 0.2 6.7 9.0 1.2 0.5 13.5 0.7 0.8 0.8 0.2 0.2 0.9 1.6 2.4 11.2 0.4 0.2 0.8 0.8 0.7 0.4 5.1 0.3 0.9 9.2 0.6 2.5 0.4 0.3 7.7 7.6 2.8 0.1 7.0 5.4 29.1 0.5 36.7 0.8 0.3 14.5 1.9 5.3 0.3 95.9 73.9 92.4 69.7 2.8 6.2 71.2 45.4 43.4 129.5 73.1 163.7 73.5 64.6 21.9 33.7 70.7 74.6 70.4 44.0 75.7 51.9 101.8 90.9 120.4 53.7 1.9 66.5 93.8 1.5 6.0 86.9 59.8 21.1 75.1 68.0 57.2 108.9 52.7 123.0 122.9 101.8 43.4 269.3 110.2 62.5 78.6 83.9 31.7 35.0 59.9 41.0 56.0 107.4 32.7 53.6 88.2 50.1 25.0 33.5 91.2 69.4 124.8 58.3 68.8 83.0 32.3 73.8 38.4 0.2 0.0 0.1 0.1 0.0 0.2 1.4 2.1 2.3 0.3 1.4 0.1 0.5 0.0 2.0 0.1 0.0 8.6 0.5 0.2 0.3 0.2 0.7 0.2 0.2 0.4 0.2 0.3 0.1 0.5 0.3 0.1 0.0 0.0 0.0 4.6 3.8 1.5 2.8 1.2 0.6 2.1 2.8 0.5 0.0 1.8 0.0 0.0 14.1 1.0 3.7 0.0 0.7 71.5 1.9 1.3 1.9 1.2 75.6 0.0 0.7 23.6 3.3 10.2 2.7 0.0 16.0 5.7 1.1 15.7 0.0 0.0 7.9 10.2 6.7 3.7 70.2 1.8 4.0 1.8 0.0 0.9 0.0 6.2 0.0 0.0 0.8 1.8 0.4 17.0 1.1 0.7 0.1 0.2 0.4 0.0 0.7 3.5 29.1 9.3 15.6 2.0 4.0 2.5 0.9 12.7 3.6 TTC39C "C18orf17, FLJ33761, HsT2697" ENSG00000168234 "Tetratricopeptide repeat domain 39C" Q8N584 18 23992773-24135610 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 94.2;retina: 143.2" "Cell type enhanced" "Detected in many" "Early spermatids: 149.8;Hepatocytes: 169.3;Late spermatids: 320.0;Rod photoreceptor cells: 241.5" "Cancer enriched" "Detected in all" 4 "liver cancer: 19.9" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "T-reg: 115.9" "Lineage enriched" "Detected in all" 4 "T-cells: 115.9" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065705, HPA065713" Approved Approved Nucleoplasm NA NA "Cluster 13: T-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 20: HeLa - Mitochondria" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "HPA065705: AB_2685538, HPA065713: AB_2685542" "prognostic favorable (1.48e-4)" "unprognostic (6.37e-2)" "unprognostic (3.66e-1)" "unprognostic (9.97e-2)" "unprognostic (4.37e-2)" "unprognostic (2.20e-3)" "unprognostic (1.13e-2)" "unprognostic (1.30e-3)" "unprognostic (2.31e-1)" "unprognostic (1.03e-1)" "unprognostic (1.78e-2)" "unprognostic (1.75e-1)" "prognostic unfavorable (2.60e-5)" "unprognostic (2.32e-1)" "unprognostic (3.51e-1)" "unprognostic (8.94e-3)" "unprognostic (4.48e-3)" 21.1 30.5 6.7 12.3 6.4 36.3 18.9 3.2 26.2 20.1 10.8 10.9 9.1 15.6 7.4 16.0 18.6 23.6 7.2 19.9 4.5 6.1 94.2 15.1 19.0 1.6 2.5 10.2 15.8 1.9 20.1 2.7 0.6 20.0 7.4 143.2 25.2 5.4 10.2 56.1 13.4 8.3 2.1 13.2 12.8 33.3 3.6 15.4 7.1 1.6 21.3 13.3 19.6 5.3 12.6 10.4 6.1 3.7 38.3 39.8 22.9 16.4 39.0 13.9 13.5 1.3 6.8 19.7 16.8 30.4 11.1 15.8 12.3 16.5 10.9 28.7 13.1 6.6 50.6 26.3 7.7 31.4 15.3 33.4 21.8 8.4 11.7 26.9 1.1 14.6 0.1 0.2 8.7 10.7 4.9 10.0 14.5 5.5 25.1 28.1 9.5 7.8 14.7 19.7 15.9 12.4 34.5 10.6 11.4 6.5 8.2 10.6 8.3 11.8 9.6 8.7 8.7 0.4 0.1 32.0 16.0 32.9 8.3 2.4 5.4 0.2 32.8 6.1 84.0 16.4 71.7 40.3 7.8 10.0 30.0 25.0 1.5 18.5 5.2 27.8 115.9 13.1 6.7 6.4 3.2 26.2 19.9 4.5 1.6 2.5 0.6 2.1 3.6 5.3 6.9 0.0 3.4 13.7 23.0 46.0 17.1 10.1 30.1 14.7 28.6 24.1 3.0 64.3 5.0 7.3 45.9 0.7 52.0 2.0 0.0 14.2 149.8 72.9 34.9 7.0 4.2 20.6 114.3 11.5 15.2 16.5 15.8 30.0 2.5 11.5 4.6 169.3 12.6 13.5 80.3 9.4 18.3 26.6 44.5 320.0 11.1 21.5 14.2 20.6 18.9 27.8 38.1 41.7 2.3 8.9 1.5 7.9 7.1 20.8 11.4 1.3 16.7 241.5 0.0 5.2 6.7 42.4 8.0 26.8 86.1 0.5 95.9 9.2 9.0 20.1 TTC6 "C14orf25, NCRNA00291" ENSG00000139865 "Tetratricopeptide repeat domain 6" Q86TZ1 14 37595847-38041442 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 7.9;prostate: 17.5" "Cell type enhanced" "Detected in some" "Breast glandular cells: 13.8;Club cells: 11.1;Early spermatids: 39.1;Late spermatids: 18.1;Spermatocytes: 10.7" "Group enriched" "Detected in some" 7 "breast cancer: 2.2;prostate cancer: 3.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 8.4;MCF7: 12.2;RT4: 8.4;T-47d: 22.8" "Not detected" "Not detected" "Region enriched" "Detected in some" 7 "midbrain: 9.7" HPA069293 Approved Centrosome NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 6: T47d - Mammary gland" "Cluster 35: Glandular cells - Unknown function" Centrosome "HPA069293: AB_2686110" "unprognostic (7.92e-2)" "unprognostic (6.95e-2)" "unprognostic (9.22e-2)" "unprognostic (1.98e-1)" "unprognostic (7.06e-2)" "unprognostic (1.22e-2)" "unprognostic (1.68e-1)" "unprognostic (3.60e-4)" "unprognostic (6.75e-2)" "unprognostic (2.07e-2)" "unprognostic (4.08e-4)" "unprognostic (5.60e-2)" "unprognostic (8.91e-8)" "unprognostic (1.76e-1)" "unprognostic (2.58e-1)" "unprognostic (1.60e-1)" "unprognostic (6.07e-3)" 0.0 0.0 0.5 0.2 0.8 0.0 7.9 0.1 0.8 0.1 1.1 1.0 0.6 0.0 0.0 0.4 0.3 0.7 0.0 0.7 1.0 0.0 3.5 1.1 0.0 2.5 5.0 0.0 0.0 0.0 0.3 0.0 1.3 17.5 0.5 0.0 2.7 0.1 0.0 0.7 0.7 0.0 3.9 0.0 3.6 5.8 3.9 0.0 0.0 0.0 0.1 1.4 0.3 1.0 0.7 0.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.6 0.0 0.4 0.0 0.0 2.4 1.3 0.2 0.0 0.0 3.4 0.0 1.2 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.0 12.2 0.0 0.0 0.0 1.7 4.5 0.0 0.0 0.0 1.0 8.4 2.4 0.0 0.0 4.5 0.0 0.0 22.8 0.0 0.0 0.0 0.3 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.8 0.1 0.8 0.7 1.0 2.5 5.0 1.3 3.9 3.9 1.0 0.2 0.0 8.4 0.3 0.1 0.0 2.8 1.5 6.2 0.0 13.8 6.9 0.8 1.5 11.1 0.0 0.0 0.0 0.2 0.4 0.0 0.0 39.1 0.0 0.0 0.4 7.7 0.0 6.4 0.0 0.0 0.4 7.1 0.1 0.0 0.0 0.0 2.5 0.0 0.0 1.0 0.7 0.0 0.0 0.0 18.1 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.8 0.4 0.0 4.9 0.0 0.0 7.5 0.0 0.0 0.2 0.4 10.7 1.9 2.3 0.0 0.0 0.3 0.0 1.1 3.1 TTK "CT96, MPH1, MPS1, MPS1L1" ENSG00000112742 "TTK protein kinase" P33981 6 80003887-80042527 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 25.3;lymphoid tissue: 46.6;testis: 34.3" "Cell type enhanced" "Detected in many" "Early spermatids: 43.3;Erythroid cells: 23.1;Late spermatids: 21.4;Spermatocytes: 130.5;Spermatogonia: 33.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "T-reg: 1.2" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB010166, CAB013229" Enhanced Approved Nucleoli,Cytosol NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoli, Cytosol" "CAB010166: AB_632567, CAB013229: AB_2533230" "unprognostic (4.27e-2)" "unprognostic (8.71e-2)" "unprognostic (1.04e-2)" "prognostic unfavorable (1.44e-5)" "unprognostic (7.97e-2)" "unprognostic (4.78e-2)" "prognostic unfavorable (3.84e-10)" "unprognostic (1.56e-3)" "unprognostic (7.95e-2)" "unprognostic (2.02e-3)" "prognostic unfavorable (2.54e-4)" "unprognostic (1.54e-1)" "unprognostic (0.00e+0)" "unprognostic (3.51e-2)" "unprognostic (1.06e-1)" "unprognostic (1.46e-1)" "unprognostic (1.66e-1)" 0.7 0.8 0.0 4.2 0.1 25.3 2.2 0.1 0.3 0.7 0.0 4.8 4.0 1.0 0.1 4.8 0.6 0.5 0.1 0.1 0.1 0.2 0.5 0.8 8.1 0.2 0.1 0.2 0.2 0.3 0.0 3.9 0.2 0.8 5.9 1.8 0.7 0.1 0.0 3.6 4.1 1.7 0.1 1.4 3.3 34.3 0.2 46.6 0.4 0.1 9.0 1.2 1.4 0.2 39.9 23.4 68.2 56.4 3.1 9.5 38.5 44.9 27.4 64.2 77.8 32.1 29.6 58.5 34.1 19.5 66.9 50.0 60.7 27.6 88.6 53.4 49.3 54.1 29.4 26.5 0.2 64.4 33.9 1.2 2.8 45.0 28.6 9.6 36.9 80.6 60.2 58.5 55.2 29.5 37.0 46.4 40.4 35.4 27.9 32.7 124.4 24.4 16.3 25.2 46.8 27.4 26.6 28.3 16.3 36.6 26.6 48.3 15.4 28.8 28.5 18.8 72.9 13.1 47.1 32.4 10.3 58.9 25.1 0.0 0.0 0.3 0.1 0.0 0.1 0.2 0.2 0.4 0.0 0.7 0.0 0.1 0.0 0.3 0.0 0.0 1.2 0.2 0.0 0.1 0.1 0.3 0.1 0.1 0.2 0.1 0.2 0.1 0.2 0.2 0.3 3.2 1.1 0.0 1.4 1.3 0.6 2.6 0.0 0.2 0.9 0.5 0.6 0.0 2.3 0.0 2.1 9.8 0.8 2.2 3.9 0.4 43.3 3.1 1.6 1.1 1.8 23.1 0.2 0.2 15.0 2.1 2.6 2.3 1.3 13.9 0.7 0.2 6.5 0.0 0.2 3.0 4.1 2.6 1.2 21.4 0.9 1.9 0.0 0.0 5.2 0.2 1.0 0.0 0.1 0.6 0.2 0.7 5.1 0.4 0.3 0.1 3.0 1.6 6.6 0.1 1.7 130.5 33.0 8.5 0.3 3.7 1.1 0.5 5.6 1.6 TTYH1 ENSG00000167614 "Tweety family member 1" Q9H313 19 54415219-54436904 "Predicted membrane proteins, Transporters" "Cell adhesion, Ion transport, Transport" "Chloride channel, Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 80.9;choroid plexus: 35.6;testis: 53.4" "Cell type enhanced" "Detected in many" "Astrocytes: 257.6;Bipolar cells: 138.6;Muller glia cells: 653.4;Oligodendrocytes: 97.5;Rod photoreceptor cells: 155.3" "Cancer enriched" "Detected in many" 15 "glioma: 63.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 7.9;AN3-CA: 11.7;U-2 OS: 2.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005725, HPA023617, HPA050655" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 5: Muller glia cells - Visual perception" "Nucleoplasm, Plasma membrane" "HPA005725: , HPA023617: AB_10600836, HPA050655: AB_2681204" "prognostic favorable (3.64e-4)" "unprognostic (1.71e-1)" "unprognostic (1.24e-2)" "unprognostic (1.25e-1)" "unprognostic (1.46e-2)" "unprognostic (2.50e-3)" "unprognostic (8.93e-2)" "unprognostic (1.51e-2)" "unprognostic (5.94e-3)" "unprognostic (1.11e-1)" "unprognostic (3.66e-1)" "unprognostic (1.60e-1)" "unprognostic (0.00e+0)" "unprognostic (2.09e-1)" "unprognostic (1.41e-1)" "unprognostic (4.45e-2)" "unprognostic (1.69e-1)" 0.9 0.9 64.3 0.0 67.9 0.0 3.5 64.0 80.9 4.0 35.6 10.0 0.2 1.6 0.0 1.1 10.4 0.2 3.6 57.6 59.7 1.2 0.7 0.2 0.0 69.4 66.5 1.5 19.4 0.0 17.7 0.0 63.5 3.5 0.0 3.2 3.6 0.4 3.3 5.9 2.6 0.0 67.6 1.4 2.5 53.4 69.3 0.0 0.3 0.0 0.0 1.7 4.2 66.8 0.1 0.0 7.9 11.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.2 0.3 0.0 0.1 0.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 1.7 0.0 0.1 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.4 0.4 0.0 0.2 0.0 0.0 0.1 2.9 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 64.3 67.9 64.0 80.9 57.6 59.7 69.4 66.5 63.5 67.6 69.3 66.8 0.4 3.2 0.6 257.6 0.4 0.8 1.2 0.6 0.0 138.6 44.3 42.2 1.3 4.3 3.0 0.0 20.9 0.9 1.3 0.2 0.0 30.4 3.9 0.3 0.9 2.8 1.2 0.0 26.4 0.6 0.7 1.5 0.0 0.7 0.0 13.7 0.7 0.1 0.3 10.1 3.3 0.0 0.0 0.0 1.5 4.8 1.8 0.3 23.2 19.7 0.3 653.4 0.0 48.2 97.5 2.2 0.0 0.7 0.1 1.9 0.4 0.7 2.8 155.3 6.6 2.3 7.8 2.2 5.1 0.0 0.9 4.2 0.6 0.5 0.3 1.9 TUFT1 ENSG00000143367 "Tuftelin 1" Q9NNX1 1 151540305-151583583 "Predicted intracellular proteins, Predicted secreted proteins" Biomineralization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 111.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 69.2;Glandular and luminal cells: 76.8;Suprabasal keratinocytes: 66.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 5.2" "Group enriched" "Detected in many" 5 "granulocytes: 5.2;T-cells: 3.5" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebellum: 41.7" "HPA028112, HPA054301" Approved Approved Approved Vesicles "Secreted - unknown location" NA Yes "Cluster 41: Basophils - Cellular respiration" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" Vesicles "HPA028112: AB_10603224, HPA054301: AB_2682442" "unprognostic (6.16e-2)" "unprognostic (3.76e-1)" "unprognostic (1.38e-1)" "prognostic unfavorable (4.83e-4)" "unprognostic (4.49e-3)" "unprognostic (1.12e-1)" "unprognostic (2.30e-2)" "unprognostic (1.37e-2)" "unprognostic (8.29e-3)" "unprognostic (9.06e-2)" "unprognostic (6.70e-3)" "unprognostic (7.88e-2)" "unprognostic (2.58e-3)" "unprognostic (1.41e-1)" "unprognostic (1.32e-1)" "unprognostic (1.82e-3)" "unprognostic (4.53e-2)" 5.6 6.8 4.7 2.8 4.2 6.7 10.1 5.0 5.3 25.4 3.4 11.6 7.5 5.3 6.3 48.1 5.1 5.9 4.9 3.8 5.9 14.1 7.0 8.4 0.9 4.0 4.0 7.4 17.2 11.4 7.2 13.3 5.2 9.6 13.0 2.1 18.3 9.2 2.5 111.5 10.8 6.2 3.3 1.5 12.8 5.4 6.2 2.2 5.7 2.7 6.2 12.4 26.8 3.5 40.7 13.7 10.0 11.5 2.3 1.9 63.1 10.7 9.5 41.3 39.6 43.6 31.5 3.5 64.6 12.5 19.5 46.4 17.6 16.2 30.1 27.0 8.7 2.2 23.0 6.7 32.2 0.8 4.7 6.5 18.9 32.5 71.6 24.5 3.4 5.0 3.6 26.8 12.8 16.8 2.0 0.5 11.7 29.6 11.4 0.1 28.1 14.2 34.7 61.8 19.5 8.0 68.2 45.8 8.0 29.4 36.5 2.1 8.6 7.4 51.7 46.2 71.7 6.6 13.7 0.5 6.3 0.9 4.7 5.2 0.6 0.7 0.3 0.1 0.7 0.6 1.0 0.5 0.9 0.2 0.8 0.3 2.5 0.1 0.3 0.1 3.5 0.5 4.7 4.2 5.0 5.3 3.8 5.9 4.0 4.0 5.2 3.3 6.2 3.5 2.1 25.6 2.0 1.6 3.8 69.2 35.2 14.7 35.9 2.5 28.8 20.2 9.8 8.6 19.0 14.7 0.0 28.1 6.6 59.5 13.7 18.2 2.7 43.2 8.9 2.7 32.2 2.7 4.4 15.2 13.9 7.0 46.9 76.8 4.5 9.0 1.1 10.5 4.0 0.0 9.3 39.1 20.3 0.0 12.7 3.2 2.5 6.5 8.8 1.0 2.0 2.1 0.0 8.5 1.8 47.4 34.6 5.3 7.7 21.7 15.4 11.2 15.9 0.5 6.6 4.1 5.5 0.6 3.5 39.6 66.5 56.8 5.8 10.9 35.7 35.6 TULP1 "LCA15, RP14, TUBL1" ENSG00000112041 "TUB like protein 1" O00294 6 35497874-35512896 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Phagocytosis, Sensory transduction, Vision" "Disease variant, Leber congenital amaurosis, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 286 "retina: 209.1" "Group enriched" "Detected in some" 5 "Cone photoreceptor cells: 266.9;Rod photoreceptor cells: 393.2" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.7;MCF7: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Intracellular and membrane" NA NA "Cluster 79: Retina - Phototransduction" "Cluster 28: BEWO - Transcription regulation" "Cluster 46: Photoreceptor cells - Phototransduction" "unprognostic (7.98e-2)" "unprognostic (2.33e-2)" "unprognostic (4.38e-2)" "unprognostic (4.60e-5)" "unprognostic (2.28e-2)" "unprognostic (3.12e-3)" "unprognostic (3.30e-1)" "unprognostic (5.49e-3)" "unprognostic (1.85e-1)" "unprognostic (2.66e-2)" "unprognostic (7.42e-2)" "unprognostic (1.66e-6)" "unprognostic (1.72e-1)" "unprognostic (1.30e-1)" "unprognostic (5.42e-2)" "unprognostic (4.11e-2)" 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.4 0.3 0.1 0.0 0.3 0.4 0.2 0.5 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.2 0.1 0.0 0.7 0.0 209.1 0.2 0.3 0.0 0.5 0.1 0.0 0.1 0.1 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 64.2 0.0 0.0 0.7 0.0 0.0 0.0 266.9 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.3 2.6 0.0 0.0 0.1 0.0 2.4 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.1 18.5 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 55.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 393.2 0.0 0.4 0.2 0.1 0.7 0.0 0.0 2.2 0.0 0.0 0.0 0.4 TYR "OCA1, OCA1A, OCAIA" ENSG00000077498 Tyrosinase P14679 11 89177875-89295759 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Melanin biosynthesis" "Monooxygenase, Oxidoreductase, Tumor antigen" "Albinism, Deafness, Disease variant, FDA approved drug targets, Waardenburg syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 37 "skin 1: 31.6" "Cell type enriched" "Detected in some" 5 "Melanocytes: 184.9" "Cancer enriched" "Detected in single" 1755 "melanoma: 351.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 995 "SK-MEL-30: 426.0" "Not detected" "Not detected" "Not detected" "Not detected" "CAB000079, HPA043241, HPA050889, HPA064583" Enhanced Enhanced Vesicles NA NA "Cluster 61: Skin - Cornification" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 23: Spermatids - Flagellum & Golgi organization" Vesicles "CAB000079: AB_564045, HPA043241: AB_2678383, HPA050889: AB_2681264, HPA064583: " "unprognostic (1.16e-1)" "unprognostic (1.01e-1)" "unprognostic (1.85e-3)" "unprognostic (9.75e-3)" 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 31.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 426.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 33.9 0.3 0.0 0.1 0.0 0.0 2.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 2.5 5.2 0.3 0.0 184.9 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 2.0 0.0 0.1 0.0 0.0 0.0 TYRP1 "b-PROTEIN, CAS2, CATB, GP75, OCA3, TRP, TYRP" ENSG00000107165 "Tyrosinase related protein 1" P17643 9 12685439-12710285 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Melanin biosynthesis" "Monooxygenase, Oxidoreductase" "Albinism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "choroid plexus: 44.8;heart muscle: 59.9;skin 1: 145.0" "Cell type enriched" "Detected in some" 17 "Melanocytes: 2486.6" "Cancer enriched" "Detected in some" 262 "melanoma: 313.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 55 "SK-MEL-30: 1395.0" "Group enriched" "Detected in some" 5 "olfactory bulb: 4.6;thalamus: 1.8" "Low region specificity" "Detected in all" "HPA000937, CAB002520" Enhanced Approved Vesicles NA NA 51000 "Cluster 61: Skin - Cornification" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "CAB002520: AB_564153, HPA000937: AB_1080437" "unprognostic (7.48e-2)" "unprognostic (1.10e-3)" "unprognostic (2.28e-1)" "unprognostic (3.16e-3)" "unprognostic (8.10e-2)" "unprognostic (3.82e-3)" "unprognostic (1.53e-1)" "unprognostic (2.25e-3)" "unprognostic (4.46e-1)" "unprognostic (8.71e-2)" "unprognostic (6.17e-2)" "unprognostic (2.42e-1)" "unprognostic (2.68e-6)" "unprognostic (1.27e-1)" "unprognostic (5.99e-2)" "unprognostic (1.95e-2)" 0.3 0.0 0.1 0.6 0.4 0.2 4.9 0.3 0.9 0.0 44.8 2.2 5.0 0.0 1.2 10.0 0.2 4.5 59.9 2.6 0.0 16.2 0.0 3.7 0.0 1.2 1.1 0.0 0.0 0.0 0.0 0.1 2.1 0.1 5.3 2.7 1.3 0.0 4.8 145.0 4.7 1.8 0.1 0.0 2.1 1.1 0.3 0.0 0.0 7.5 0.0 1.1 0.4 1.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.3 0.0 0.0 25.1 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.5 0.0 0.0 4.3 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.2 0.0 0.0 1395.0 0.1 19.5 1.5 0.0 0.0 0.7 0.0 0.9 0.0 0.7 0.4 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.3 0.9 2.6 0.0 1.2 1.1 2.1 0.1 0.3 1.0 0.0 0.0 0.0 0.0 0.0 92.3 0.1 0.0 0.0 11.7 0.0 0.0 44.3 0.0 0.0 3.7 2.1 0.0 0.0 0.0 144.8 0.3 2.5 0.0 0.0 1.3 0.0 0.0 0.9 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 17.5 4.7 0.3 0.0 2486.6 0.0 0.0 15.9 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 1.6 0.0 0.0 1.4 0.7 0.7 0.0 16.8 0.0 0.5 0.0 0.0 0.2 UBASH3B "KIAA1959, STS-1, TULA-2, TULA2" ENSG00000154127 "Ubiquitin associated and SH3 domain containing B" Q8TF42 11 122655722-122814473 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 15.0;lymphoid tissue: 15.6;placenta: 13.8" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 54.9;Inhibitory neurons: 166.3;Langerhans cells: 51.2;Syncytiotrophoblasts: 47.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 122.2;HMC-1: 88.9;hTEC/SVTERT24-B: 72.9;REH: 73.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038605, HPA038606, HPA038607" Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 23000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "Nucleoplasm, Nuclear bodies" "HPA038605: AB_10669648, HPA038606: , HPA038607: AB_2676112" "unprognostic (4.94e-2)" "unprognostic (6.03e-3)" "unprognostic (1.34e-1)" "unprognostic (2.98e-1)" "unprognostic (2.02e-1)" "unprognostic (1.49e-1)" "unprognostic (9.09e-2)" "unprognostic (4.67e-3)" "unprognostic (1.21e-1)" "unprognostic (1.95e-1)" "unprognostic (1.46e-3)" "unprognostic (6.20e-2)" "unprognostic (9.02e-3)" "unprognostic (1.54e-1)" "unprognostic (3.22e-2)" "unprognostic (2.72e-3)" "unprognostic (1.53e-1)" 3.4 0.7 1.1 4.8 1.5 6.7 1.1 15.0 1.9 3.0 0.1 1.2 1.3 1.0 0.2 1.1 0.5 1.9 0.9 1.2 5.5 1.7 1.3 4.6 5.7 10.3 7.1 0.2 0.6 0.4 0.3 13.8 10.2 0.7 1.4 1.9 0.7 0.7 1.1 3.4 1.7 1.9 1.2 15.6 1.4 1.2 2.8 15.1 2.3 0.3 3.2 4.4 0.5 1.4 13.1 31.5 5.6 7.5 2.4 4.4 29.1 45.6 25.1 18.1 13.9 12.5 6.8 5.3 3.5 24.3 17.2 6.4 0.1 16.3 28.7 0.2 0.9 122.2 1.0 10.8 6.7 15.0 88.9 3.9 1.0 72.9 26.9 19.7 12.4 5.3 0.1 0.1 17.8 0.5 18.5 9.6 2.5 13.3 7.4 73.3 3.3 0.7 28.6 10.9 12.7 0.2 12.1 0.9 10.1 11.7 0.2 4.0 32.3 23.4 12.6 13.9 19.1 1.0 0.0 15.1 12.4 20.6 43.4 0.0 1.3 9.9 1.8 6.3 1.9 0.3 2.3 1.7 1.7 1.1 2.6 1.4 2.7 6.4 11.1 0.2 4.7 1.8 1.1 1.5 15.0 1.9 1.2 5.5 10.3 7.1 10.2 1.2 2.8 1.4 2.2 0.0 4.7 9.1 4.6 7.1 4.2 3.4 2.8 1.8 1.2 1.3 1.1 0.0 2.0 3.7 0.0 32.5 10.0 0.6 0.0 8.4 2.4 0.6 4.0 4.5 0.0 1.7 24.8 9.7 54.9 4.9 2.0 1.5 12.7 11.5 5.0 0.6 35.7 11.8 166.3 0.5 4.1 26.0 51.2 3.9 0.0 26.5 1.8 30.0 9.1 0.2 17.5 26.2 2.7 26.3 0.3 0.4 11.4 4.7 0.2 0.6 2.5 1.1 0.0 3.8 3.4 0.1 0.8 2.4 6.0 47.6 16.8 0.1 0.4 3.1 UBE2C UBCH10 ENSG00000175063 "Ubiquitin conjugating enzyme E2 C" O00762 20 45812576-45816957 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 78.5;lymphoid tissue: 113.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 129.6;Erythroid cells: 182.1;Extravillous trophoblasts: 449.1;Granulosa cells: 119.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "T-reg: 8.2" "Group enriched" "Detected in many" 5 "granulocytes: 2.1;NK-cells: 2.1;T-cells: 8.2" "Low cell line specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basal ganglia: 4.3;white matter: 11.4" "Low region specificity" "Detected in some" "CAB011464, HPA034569, CAB035990, HPA054975" Approved Approved "Plasma membrane,Cytosol" Yes Yes "Cluster 35: T-regs - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Cytosol" "CAB011464: AB_442965, CAB035990: , HPA034569: AB_2674226, HPA054975: AB_2682658" "unprognostic (1.45e-2)" "unprognostic (2.19e-1)" "unprognostic (1.06e-1)" "unprognostic (2.11e-3)" "unprognostic (2.54e-1)" "unprognostic (1.35e-1)" "prognostic unfavorable (6.24e-6)" "unprognostic (2.27e-3)" "unprognostic (2.59e-2)" "unprognostic (1.04e-1)" "prognostic unfavorable (6.91e-4)" "unprognostic (3.76e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.09e-1)" "unprognostic (3.61e-1)" "unprognostic (4.65e-2)" "unprognostic (2.68e-1)" 2.6 2.9 0.3 21.5 0.3 78.5 4.3 0.9 0.6 6.1 0.7 26.7 21.4 5.7 0.6 37.2 1.9 2.7 1.4 0.2 0.3 1.9 2.9 5.4 45.3 0.3 0.7 1.3 1.0 0.4 0.4 20.4 0.7 1.5 30.9 0.2 5.0 0.9 0.9 18.5 20.6 10.5 0.2 15.8 13.0 16.4 1.6 113.5 1.1 0.2 69.5 6.9 12.3 0.4 312.8 223.9 390.9 188.3 10.4 24.0 225.2 238.5 121.6 390.7 278.4 743.8 345.4 327.6 233.2 115.5 475.6 294.9 2.2 260.5 395.8 141.7 213.7 101.5 168.5 196.0 3.0 145.4 241.6 7.6 27.8 265.7 257.3 57.4 193.4 206.4 1.8 261.6 325.4 516.2 243.5 41.1 237.1 350.8 529.4 256.0 354.8 1.4 134.9 105.9 226.1 188.7 378.3 271.7 154.4 196.2 276.6 209.4 70.1 341.2 298.4 236.2 473.4 84.3 2.9 369.4 208.0 103.4 328.6 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.8 1.7 0.6 0.1 0.1 0.1 2.1 2.1 0.5 0.3 8.2 3.2 0.3 0.3 0.9 0.6 0.2 0.3 0.3 0.7 0.7 0.2 1.6 0.4 0.9 0.0 3.7 0.0 17.9 17.3 7.8 39.0 5.7 0.0 8.6 14.6 0.0 1.5 9.3 0.0 0.0 129.6 3.6 27.4 0.0 1.3 12.0 5.8 5.9 9.5 1.2 182.1 0.0 0.5 449.1 28.5 25.5 9.6 5.7 119.0 18.2 3.6 92.6 0.0 0.1 41.1 50.8 20.8 18.1 6.4 0.9 24.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 1.5 7.2 0.0 37.0 12.6 6.2 0.6 1.8 0.0 0.0 0.5 19.2 52.2 50.7 83.2 11.6 31.2 13.7 2.5 68.4 18.4 UBE2T "FANCT, HSPC150" ENSG00000077152 "Ubiquitin conjugating enzyme E2 T" Q9NPD8 1 202331657-202341980 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 47.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 74.5;Erythroid cells: 134.3;Extravillous trophoblasts: 103.4;Spermatocytes: 114.1;Spermatogonia: 113.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA002831 Approved Nucleoplasm,Nucleoli NA Yes "Cluster 27: Non-specific - Gene expression" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoli Nucleoplasm "HPA002831: AB_1080445" "unprognostic (2.38e-3)" "unprognostic (6.37e-2)" "unprognostic (5.27e-2)" "unprognostic (5.19e-2)" "unprognostic (2.81e-1)" "unprognostic (6.13e-3)" "prognostic unfavorable (4.79e-6)" "unprognostic (1.71e-2)" "unprognostic (2.32e-2)" "prognostic favorable (6.90e-6)" "unprognostic (6.28e-3)" "unprognostic (2.85e-2)" "prognostic unfavorable (2.22e-16)" "unprognostic (5.37e-3)" "unprognostic (1.58e-1)" "unprognostic (1.20e-1)" "unprognostic (4.86e-2)" 2.3 3.7 6.6 10.4 6.5 28.7 4.5 5.8 13.7 4.1 5.0 13.1 8.7 4.5 4.4 10.6 3.3 2.5 11.3 6.8 7.4 3.5 3.2 3.0 19.0 6.5 6.6 1.0 0.7 4.4 3.0 10.1 6.9 2.1 15.5 2.5 2.7 3.1 17.2 5.3 8.2 9.4 6.0 6.2 4.7 19.3 6.7 47.1 2.9 13.0 18.6 6.3 5.0 6.1 123.3 111.6 167.1 79.8 15.4 27.9 94.2 130.2 72.8 146.0 102.6 79.9 147.1 140.4 50.0 47.0 108.4 98.6 154.1 76.7 131.2 128.1 87.2 85.6 54.0 93.8 6.9 105.2 102.0 9.8 18.1 114.0 47.2 34.3 85.8 157.4 111.0 114.0 116.4 113.3 190.8 135.1 65.4 126.9 57.4 145.0 176.2 122.9 57.1 58.1 131.3 132.8 90.2 112.1 44.8 49.8 117.1 64.6 41.8 65.7 104.6 116.1 159.6 57.8 120.1 182.9 64.5 107.0 139.1 0.0 0.7 1.7 3.3 2.3 2.5 8.5 4.5 3.3 1.7 6.6 6.4 7.1 0.0 1.2 8.9 3.4 10.8 2.4 6.6 6.5 5.8 13.7 6.8 7.4 6.5 6.6 6.9 6.0 6.7 6.1 1.9 0.0 2.2 1.3 13.3 14.3 10.4 29.9 2.8 6.4 6.3 8.6 12.8 0.0 12.1 5.5 0.0 74.5 5.4 10.1 5.9 10.9 24.4 15.7 7.6 5.3 1.2 134.3 8.3 7.5 103.4 11.8 10.7 6.7 8.8 32.2 3.9 2.4 27.7 10.1 6.1 14.4 32.6 1.9 5.4 8.2 3.1 5.8 3.6 1.9 2.6 1.6 0.0 1.0 1.4 10.3 2.9 4.1 32.1 5.2 3.3 12.2 16.2 1.2 6.6 0.8 11.3 114.1 113.1 15.5 10.9 22.4 9.3 12.1 30.5 11.3 UGT2A1 ENSG00000173610 "UDP glucuronosyltransferase family 2 member A1 complex locus" P0DTE4 4 69588417-69653249 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Olfaction, Sensory transduction" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "choroid plexus: 3.6;kidney: 2.3;liver: 3.6;pituitary gland: 5.6" "Cell type enriched" "Detected in some" 18 "Proximal tubular cells: 107.9" "Cancer enhanced" "Detected in some" "liver cancer: 0.7;lung cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA017261, HPA045108" Uncertain NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA017261: AB_10963582, HPA045108: AB_2679218" "unprognostic (3.93e-3)" "unprognostic (5.62e-1)" "unprognostic (1.28e-4)" "unprognostic (1.74e-1)" "unprognostic (2.76e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.3 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 3.7 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 107.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 UPB1 BUP1 ENSG00000100024 "Beta-ureidopropionase 1" Q9UBR1 22 24494107-24528390 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "liver: 216.0" "Group enriched" "Detected in many" 5 "Hepatocytes: 146.5;Proximal tubular cells: 68.5" "Cancer enriched" "Detected in some" 8 "liver cancer: 25.4" "Region enhanced" "Detected in single" "cerebral cortex: 1.8" "Group enriched" "Detected in some" 14 "basophil: 2.1;neutrophil: 2.1" "Lineage enriched" "Detected in single" 14 "granulocytes: 2.1" "Cell line enriched" "Detected in single" 7 "CACO-2: 3.3" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA000728, HPA076321" Enhanced NA NA 1400000 "Cluster 17: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA000728: AB_1080471, HPA076321: " "unprognostic (7.27e-2)" "unprognostic (4.57e-3)" "unprognostic (2.27e-1)" "unprognostic (7.62e-2)" "unprognostic (1.97e-1)" "unprognostic (1.09e-4)" "prognostic favorable (2.30e-7)" "unprognostic (8.41e-2)" "unprognostic (1.06e-1)" "unprognostic (2.93e-1)" "unprognostic (4.89e-6)" "unprognostic (3.82e-2)" "unprognostic (1.93e-2)" "unprognostic (1.81e-1)" "unprognostic (2.56e-1)" "unprognostic (1.99e-1)" "unprognostic (4.63e-3)" 0.2 0.2 0.2 0.2 0.6 2.0 0.1 0.7 1.8 0.2 0.2 0.2 1.2 0.2 0.2 0.1 0.3 0.1 1.9 0.2 0.0 25.7 216.0 0.8 0.2 0.1 0.1 0.2 0.1 0.0 0.4 0.0 0.4 0.3 0.1 1.1 0.1 0.1 0.5 0.9 0.4 0.1 0.0 0.8 0.2 3.0 0.4 0.6 0.1 0.2 0.1 0.1 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 3.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.3 0.1 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.2 0.4 0.0 2.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.1 0.0 0.0 0.0 0.0 0.2 0.6 0.7 1.8 0.2 0.0 0.1 0.1 0.4 0.0 0.4 0.1 0.8 0.0 2.0 0.3 0.6 0.6 1.3 0.1 0.0 4.0 0.3 0.3 2.4 4.3 0.0 1.8 10.4 0.1 0.1 0.0 11.7 0.1 1.2 0.2 0.6 1.9 2.4 5.3 0.7 0.4 0.1 1.4 0.0 0.5 0.0 0.6 3.6 146.5 0.1 0.0 1.2 0.0 0.0 5.1 2.7 1.4 0.3 1.0 0.0 0.0 21.3 0.4 0.0 0.0 0.3 0.0 0.1 0.0 0.7 1.2 0.0 68.5 0.0 1.8 0.0 2.7 3.7 12.8 6.8 0.0 1.1 0.3 0.9 0.2 0.1 1.1 VIL1 "D2S1471, VIL" ENSG00000127831 "Villin 1" P09327 2 218419121-218453295 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" Apoptosis "Actin capping, Actin-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "intestine: 436.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 243.8;Enteroendocrine cells: 113.6;Intestinal goblet cells: 143.6;Paneth cells: 216.2;Proximal enterocytes: 558.5;Undifferentiated cells: 161.8" "Group enriched" "Detected in many" 4 "colorectal cancer: 56.4;stomach cancer: 23.5" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 4 "neutrophil: 1.3" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.3" "Group enriched" "Detected in some" 97 "CACO-2: 762.5;Hep G2: 365.3;OE19: 321.9" "Low region specificity" "Detected in single" "Not detected" "Not detected" "CAB002452, HPA006884, HPA006885" Enhanced Enhanced "Plasma membrane" NA NA 6800 "Cluster 9: Neutrophils - Innate immune response" "Cluster 9: Intestine - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "CAB002452: AB_564052, HPA006884: AB_1080566, HPA006885: AB_1080564" "unprognostic (1.28e-1)" "unprognostic (1.91e-2)" "unprognostic (1.61e-2)" "unprognostic (1.09e-1)" "unprognostic (1.83e-1)" "unprognostic (3.36e-1)" "unprognostic (3.03e-1)" "unprognostic (5.90e-2)" "unprognostic (2.44e-2)" "unprognostic (7.06e-2)" "unprognostic (4.14e-1)" "unprognostic (1.03e-1)" "unprognostic (2.25e-3)" "unprognostic (3.90e-1)" "unprognostic (2.58e-1)" "unprognostic (4.79e-2)" "unprognostic (4.65e-2)" 0.6 1.1 0.0 10.3 0.1 0.3 0.8 0.3 0.2 0.7 0.0 175.9 395.0 0.5 0.0 0.9 0.7 28.1 1.0 0.0 0.0 25.9 31.4 0.7 0.3 0.0 0.0 1.1 29.4 0.0 1.4 0.3 0.0 1.0 184.0 0.0 0.6 0.4 0.4 1.1 436.3 8.1 0.0 1.2 6.9 2.0 0.0 0.0 0.6 0.0 0.0 0.8 0.9 0.1 0.0 1.5 0.0 0.1 0.0 0.1 1.0 0.0 0.0 0.0 0.0 762.5 0.5 0.1 5.0 0.0 0.5 0.1 0.3 0.0 0.0 0.0 0.4 0.0 0.3 365.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.4 0.1 0.0 0.1 0.0 1.7 0.8 321.9 0.0 0.0 0.0 1.4 0.0 0.2 0.3 0.7 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.2 0.0 4.0 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 1.3 0.8 0.4 0.1 0.0 1.8 0.3 0.6 0.5 24.3 0.1 0.0 2.1 0.3 0.8 243.8 3.9 12.3 1.9 1.3 0.9 0.4 113.6 3.2 0.7 42.9 0.2 0.8 6.6 1.6 8.9 0.3 0.7 32.6 0.1 1.7 0.5 143.6 0.0 2.2 1.5 0.5 0.0 5.1 0.0 0.0 0.2 0.5 0.0 0.0 0.3 10.9 216.2 0.0 0.3 0.9 558.5 35.1 0.0 1.2 0.0 1.7 0.7 0.8 0.8 0.6 0.9 0.3 1.5 0.0 161.8 0.3 WDR47 KIAA0893 ENSG00000085433 "WD repeat domain 47" O94967 1 108970214-109042113 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 93.6;Suprabasal keratinocytes: 104.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027287, HPA027289" Approved Approved "Nucleoplasm,Actin filaments" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 58: Brain - Synaptic function" "Cluster 18: U-2197 - ECM organization" "Cluster 28: Keratinocytes - Keratinization" "Actin filaments" Nucleoplasm "HPA027287: AB_10599416, HPA027289: AB_10601862" "unprognostic (8.55e-2)" "unprognostic (3.36e-2)" "unprognostic (7.51e-2)" "unprognostic (2.44e-1)" "unprognostic (4.90e-1)" "prognostic favorable (9.86e-4)" "unprognostic (4.05e-3)" "unprognostic (2.83e-2)" "unprognostic (2.87e-1)" "unprognostic (3.67e-2)" "unprognostic (2.71e-2)" "unprognostic (1.93e-1)" "unprognostic (8.39e-3)" "unprognostic (7.90e-3)" "unprognostic (9.23e-2)" "unprognostic (2.73e-2)" "unprognostic (8.09e-2)" 7.8 7.1 22.6 5.5 26.6 12.2 6.3 14.1 27.3 8.8 1.5 8.0 3.7 9.3 5.7 14.4 8.5 7.3 8.1 27.7 17.9 7.6 3.5 7.0 5.6 13.4 11.0 7.5 5.9 9.2 5.3 6.5 14.6 7.3 5.3 37.0 5.8 7.0 17.0 22.9 4.5 10.2 10.9 5.7 6.0 22.7 16.7 7.7 6.2 15.3 7.5 7.5 8.9 19.5 15.6 4.7 8.8 10.9 17.0 14.8 4.7 17.4 10.7 11.4 12.7 4.6 2.3 7.0 9.0 16.7 8.4 17.1 12.5 7.6 15.0 13.1 7.0 5.8 9.9 5.3 9.7 9.2 8.3 9.2 12.4 17.9 8.5 13.8 13.7 8.1 3.5 9.5 19.4 9.3 8.9 7.2 3.7 5.0 9.1 12.5 22.3 3.9 19.0 13.3 15.3 14.0 15.2 8.1 12.5 9.4 3.7 9.3 23.5 15.1 7.0 26.7 14.5 6.1 5.4 5.5 17.6 9.0 23.0 18.0 5.4 7.1 3.3 5.7 3.1 2.4 3.1 3.5 5.8 3.4 2.8 2.5 22.0 2.7 5.9 6.3 5.5 2.6 22.6 26.6 14.1 27.3 27.7 17.9 13.4 11.0 14.6 10.9 16.7 19.5 16.5 12.8 6.5 33.3 13.8 93.6 5.1 7.7 62.0 15.3 11.1 12.6 18.9 10.0 8.0 7.3 45.9 2.4 25.1 2.7 5.9 3.5 33.2 20.5 9.3 12.1 3.0 1.7 46.2 0.9 2.1 10.7 8.2 10.4 2.5 5.6 7.1 2.0 4.4 11.8 39.1 1.0 4.1 5.5 28.4 41.4 8.4 13.9 24.9 19.7 6.3 13.2 8.2 15.1 26.5 3.9 0.9 15.1 14.9 2.4 2.4 5.5 18.9 32.3 6.6 13.5 16.5 32.2 28.9 52.1 104.4 4.9 18.9 3.3 2.1 4.1 WFDC6 "C20orf171, dJ461P17.11, WAP6" ENSG00000243543 "WAP four-disulfide core domain 6" Q9BQY6 20 45534196-45539482 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "epididymis: 250.9" "Cell type enriched" "Detected in some" 4 "Respiratory ciliated cells: 34.2" "Cancer enhanced" "Detected in some" "endometrial cancer: 0.9;testis cancer: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "U-87 MG: 2.6" "Secreted in male reproductive system" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (3.68e-3)" "unprognostic (2.21e-3)" "unprognostic (1.26e-2)" "unprognostic (8.74e-2)" "unprognostic (2.91e-2)" 0.2 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.4 1.0 0.0 0.0 0.0 0.2 250.9 0.1 7.7 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.9 0.0 0.5 0.1 0.0 0.0 0.0 0.0 37.6 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 6.8 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 34.2 0.0 0.0 0.0 0.2 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 WNT7B ENSG00000188064 "Wnt family member 7B" P56706 22 45920366-45977162 "Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 12.4;skin 1: 17.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 33.6;Basal prostatic cells: 26.4;Basal squamous epithelial cells: 42.1;Club cells: 23.9;Pancreatic endocrine cells: 43.3;Prostatic glandular cells: 26.2;Urothelial cells: 46.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 119.4;HeLa: 103.7;RPTEC TERT1: 41.4;SK-BR-3: 51.0;U-87 MG: 93.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" "unprognostic (2.02e-3)" "unprognostic (7.83e-3)" "unprognostic (8.51e-2)" "unprognostic (2.93e-2)" "unprognostic (3.26e-2)" "unprognostic (1.31e-1)" "unprognostic (1.85e-2)" "unprognostic (2.74e-1)" "unprognostic (2.01e-1)" "unprognostic (4.05e-2)" "unprognostic (3.85e-3)" "unprognostic (1.69e-2)" "unprognostic (8.58e-4)" "unprognostic (1.90e-1)" "unprognostic (6.73e-2)" "unprognostic (1.36e-1)" "unprognostic (1.22e-2)" 0.0 0.0 4.6 0.0 3.4 0.0 1.1 1.8 5.1 3.5 0.4 0.0 0.0 0.1 0.1 12.4 1.2 2.9 0.0 4.9 4.5 6.3 0.1 3.1 0.0 2.7 2.3 0.0 0.5 0.1 0.5 0.4 4.3 4.4 0.0 0.0 2.2 1.9 0.0 17.9 0.0 0.0 1.7 0.0 0.0 0.3 5.4 0.7 0.3 0.0 1.0 9.1 8.3 1.9 23.2 119.4 0.3 0.0 0.0 0.0 15.2 0.4 1.3 0.0 0.0 0.5 15.5 0.1 3.7 0.2 1.3 25.8 0.9 15.1 0.0 0.1 1.0 0.0 103.7 0.6 0.0 0.0 0.1 0.0 10.2 0.1 3.0 0.4 0.0 0.0 0.0 0.2 0.0 33.1 0.0 0.0 0.1 9.7 22.4 0.0 0.0 1.3 41.4 33.9 4.3 0.0 10.3 51.0 0.0 0.2 8.5 13.6 0.0 2.1 1.8 0.0 1.0 0.0 0.0 0.0 93.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.6 3.4 1.8 5.1 4.9 4.5 2.7 2.3 4.3 1.7 5.4 1.9 0.3 6.4 15.6 3.9 0.5 33.6 26.4 16.3 42.1 0.5 4.0 0.6 1.6 8.6 23.9 12.9 4.2 3.5 0.1 0.1 0.0 5.9 0.3 1.7 0.4 0.7 0.0 0.0 0.3 0.5 0.3 1.7 0.0 4.3 2.5 0.2 0.4 0.1 0.1 0.0 1.2 0.0 0.0 0.0 3.7 0.2 0.3 0.3 0.0 1.0 1.0 0.2 0.0 7.5 0.1 43.3 0.0 0.4 1.5 26.2 0.0 0.1 13.8 1.1 0.0 0.8 1.9 0.2 1.8 21.0 20.5 0.7 0.5 0.0 0.0 46.6 XKRX "XKR2, XPLAC" ENSG00000182489 "XK related X-linked" Q6PP77 X 100913445-100929433 "Predicted membrane proteins, Transporters" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "skin 1: 9.7" "Cell type enhanced" "Detected in some" "Astrocytes: 9.4;Excitatory neurons: 4.3;Inhibitory neurons: 6.0;Microglial cells: 3.7;Oligodendrocytes: 5.5;Syncytiotrophoblasts: 2.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 5 "naive B-cell: 1.9;naive CD4 T-cell: 1.5;naive CD8 T-cell: 1.2" "Group enriched" "Detected in many" 18 "B-cells: 1.9;T-cells: 1.5" "Cell line enriched" "Detected in some" 5 "CACO-2: 8.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 31: Skin - Epidermis development" "Cluster 39: CACO-2 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (3.35e-1)" "unprognostic (2.38e-2)" "unprognostic (4.51e-3)" "unprognostic (1.87e-1)" "unprognostic (8.53e-2)" "unprognostic (2.67e-2)" "unprognostic (2.96e-2)" "unprognostic (5.18e-2)" "unprognostic (3.69e-2)" "unprognostic (7.37e-2)" "unprognostic (5.70e-2)" "unprognostic (1.58e-2)" "unprognostic (5.60e-6)" "unprognostic (1.25e-1)" "unprognostic (2.60e-1)" "prognostic favorable (3.52e-4)" "unprognostic (1.18e-1)" 0.0 0.6 0.5 0.8 0.3 0.1 0.6 0.1 0.3 0.7 0.0 0.7 0.3 0.2 1.1 2.3 0.6 0.1 0.0 0.2 1.7 0.1 0.0 1.2 1.6 0.3 0.4 0.2 0.0 0.0 1.0 0.3 0.3 0.3 0.8 0.2 0.5 0.9 0.1 9.7 2.4 0.1 0.2 0.5 0.3 0.2 1.2 1.8 0.4 0.0 3.5 0.3 1.7 0.2 0.2 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 8.2 1.0 0.6 0.0 0.0 0.7 0.1 0.0 0.6 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 1.5 0.6 0.0 0.0 0.0 0.4 0.1 0.0 0.3 1.6 0.0 0.0 0.0 1.6 0.1 1.3 0.2 0.7 0.1 0.7 0.0 0.1 0.2 0.0 1.4 0.0 0.2 0.0 0.0 1.2 0.3 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 1.9 1.5 1.2 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.3 0.1 0.3 0.2 1.7 0.3 0.4 0.3 0.2 1.2 0.2 0.0 0.0 0.0 9.4 0.7 0.0 0.1 0.5 0.0 0.3 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 6.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 1.8 3.7 0.1 0.2 0.0 1.0 5.5 0.1 0.1 0.0 0.0 0.1 1.2 0.0 0.5 0.1 0.0 0.0 0.0 0.1 0.3 1.0 0.9 2.6 0.2 0.0 0.2 0.4 YBX2 "Contrin, CSDA3, MSY2" ENSG00000006047 "Y-box binding protein 2" Q9Y2T7 17 7288263-7294639 "Predicted intracellular proteins, Transcription factors" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 77 "testis: 551.1" "Group enriched" "Detected in some" 18 "Early spermatids: 346.9;Late spermatids: 427.3;Spermatocytes: 234.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 4.8;MCF7: 8.7;SH-SY5Y: 3.2;SK-BR-3: 3.9;T-47d: 12.6" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" "CAB012332, HPA053904, HPA056744" Enhanced NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 6: T47d - Mammary gland" "Cluster 66: Spermatocytes - Spermatogenesis" "CAB012332: AB_776541, HPA053904: AB_2682302, HPA056744: AB_2683223" "unprognostic (1.76e-2)" "unprognostic (4.62e-3)" "unprognostic (3.99e-2)" "prognostic unfavorable (6.50e-5)" "unprognostic (9.80e-4)" "unprognostic (4.68e-2)" "unprognostic (2.23e-1)" "unprognostic (3.44e-1)" "unprognostic (1.41e-1)" "unprognostic (1.20e-1)" "unprognostic (2.20e-1)" "unprognostic (1.38e-1)" "unprognostic (2.38e-4)" "unprognostic (1.78e-2)" "unprognostic (2.15e-1)" "unprognostic (5.31e-1)" "unprognostic (2.35e-2)" 3.0 0.1 0.5 0.1 0.6 0.2 3.2 0.4 1.1 2.4 0.1 7.2 1.0 1.3 0.0 2.0 2.3 0.0 1.4 0.9 0.5 1.1 1.9 0.1 0.0 0.9 0.7 0.3 0.3 0.3 0.5 0.0 0.6 1.4 0.3 0.0 1.2 0.8 2.0 1.4 4.0 0.5 0.5 0.1 1.2 551.1 0.9 0.0 1.1 0.1 0.0 1.0 0.9 0.8 0.0 0.0 0.0 0.8 0.0 0.0 1.5 0.0 0.0 0.0 0.0 4.8 2.3 0.0 2.4 0.0 0.0 0.4 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 8.7 0.3 0.4 1.5 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 3.2 1.3 3.9 0.3 2.0 12.6 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.4 1.1 0.9 0.5 0.9 0.7 0.6 0.5 0.9 0.8 0.6 0.0 0.0 0.3 0.0 0.6 0.1 0.1 0.0 0.2 2.8 3.3 4.4 0.0 0.3 1.8 0.0 0.2 0.5 18.0 0.0 0.1 346.9 0.7 0.1 0.7 4.8 0.0 0.5 0.2 0.4 0.4 0.0 0.4 0.0 0.0 0.0 1.5 0.1 0.0 0.1 8.2 0.0 0.0 0.0 427.3 6.8 0.7 3.6 0.0 0.0 0.8 0.0 0.0 0.1 0.0 9.9 6.8 0.0 0.3 10.0 0.4 0.3 0.5 0.0 0.4 1.2 234.3 12.0 1.8 0.9 0.1 0.1 0.1 15.2 1.1 ZDHHC5 "DHHC5, KIAA1748, ZNF375" ENSG00000156599 "Zinc finger DHHC-type palmitoyltransferase 5" Q9C0B5 11 57667747-57701182 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014670 Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 15: RT4 - Unknown function" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane" Nucleoplasm "HPA014670: AB_2257442" "unprognostic (1.34e-1)" "unprognostic (3.47e-2)" "unprognostic (2.51e-1)" "unprognostic (2.29e-1)" "unprognostic (5.32e-2)" "unprognostic (1.70e-2)" "unprognostic (9.82e-3)" "unprognostic (1.74e-3)" "unprognostic (4.36e-2)" "unprognostic (9.78e-2)" "prognostic unfavorable (6.74e-5)" "unprognostic (1.76e-1)" "unprognostic (4.72e-3)" "unprognostic (2.16e-1)" "unprognostic (6.80e-2)" "unprognostic (2.06e-2)" "unprognostic (1.74e-3)" 29.0 21.7 8.3 27.2 7.8 29.2 25.8 8.3 9.5 27.0 11.0 36.4 29.6 22.3 24.1 60.9 25.0 27.9 27.9 7.5 9.2 28.2 36.7 29.0 24.4 8.5 8.9 20.7 31.6 45.3 12.6 36.7 8.7 28.0 34.4 35.9 35.0 26.7 40.9 45.2 31.0 29.0 6.9 25.5 30.2 36.2 10.9 30.6 36.9 45.5 35.0 42.3 28.7 8.9 80.3 86.2 33.7 34.7 74.9 57.4 64.9 72.8 89.8 61.8 46.3 52.3 97.0 53.4 91.9 89.5 53.1 110.1 53.6 88.9 55.4 66.5 24.4 45.8 40.1 49.3 81.5 85.9 73.7 81.3 79.3 88.8 92.9 51.1 71.0 45.6 61.5 66.2 79.7 48.4 49.1 29.3 41.1 61.0 52.2 47.8 66.6 67.1 74.8 115.2 25.3 30.7 67.6 77.0 78.5 45.4 81.9 52.6 80.7 76.5 40.7 82.9 52.2 48.2 63.0 45.9 59.1 44.4 68.0 11.6 5.2 7.1 6.9 6.8 8.3 5.8 6.7 6.0 5.4 5.7 6.7 6.9 6.9 5.0 8.1 9.0 7.0 6.8 8.3 7.8 8.3 9.5 7.5 9.2 8.5 8.9 8.7 6.9 10.9 8.9 28.8 16.0 10.5 14.7 13.4 16.2 12.7 13.7 16.5 21.4 20.4 15.2 21.6 12.8 19.8 12.9 37.5 10.1 20.3 41.3 3.9 14.4 21.3 19.9 22.1 17.1 11.5 10.8 16.4 18.2 9.9 15.5 15.8 35.5 19.7 24.9 16.1 15.1 13.0 13.5 17.9 17.5 18.3 16.3 10.2 9.8 11.8 18.4 1.8 14.0 16.0 14.0 17.5 17.6 14.7 26.0 20.8 7.5 12.4 15.1 22.9 11.4 17.4 47.7 0.0 18.4 18.5 13.3 7.1 31.5 19.9 18.6 15.9 16.8 19.7 20.5 ZNF385A "DKFZp586G1122, Hzf, ZFP385, ZNF385" ENSG00000161642 "Zinc finger protein 385A" Q96PM9 12 54369133-54391298 "Predicted intracellular proteins" "DNA damage, Transcription, Transcription regulation, Translation regulation" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 159.3;retina: 250.6;skin 1: 159.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 212.8;Cone photoreceptor cells: 171.0;Horizontal cells: 144.7;Muller glia cells: 142.6;Rod photoreceptor cells: 209.7;Syncytiotrophoblasts: 108.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "classical monocyte: 29.2;intermediate monocyte: 32.8;myeloid DC: 31.9;non-classical monocyte: 25.7" "Group enriched" "Detected in many" 11 "dendritic cells: 31.9;monocytes: 32.8" "Cell line enhanced" "Detected in many" "HaCaT: 89.5;HBEC3-KT: 85.7;HEL: 109.5;hTCEpi: 94.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039799 Supported Nucleoplasm,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 30: Epithelial cell lines - Translation" "Cluster 56: Bipolar cells - Visual perception" "Nucleoplasm, Cytosol" "HPA039799: AB_10795117" "unprognostic (8.56e-2)" "unprognostic (1.43e-1)" "prognostic unfavorable (5.20e-4)" "unprognostic (6.70e-2)" "unprognostic (1.07e-2)" "unprognostic (1.79e-3)" "unprognostic (2.30e-2)" "unprognostic (1.21e-1)" "unprognostic (2.75e-1)" "unprognostic (1.30e-1)" "unprognostic (1.42e-1)" "unprognostic (2.12e-1)" "prognostic unfavorable (9.75e-5)" "unprognostic (1.00e-1)" "unprognostic (3.68e-2)" "unprognostic (2.43e-1)" "unprognostic (6.07e-3)" 43.3 10.1 76.8 28.6 87.9 32.8 22.2 96.9 86.3 29.2 57.7 13.8 7.2 7.6 16.6 99.5 9.7 14.2 13.7 60.2 89.8 10.2 6.4 19.1 15.3 105.5 111.9 5.3 3.3 26.6 26.7 19.4 93.9 34.9 8.0 250.6 28.1 15.0 21.9 159.8 15.8 14.2 95.1 24.8 10.4 2.4 159.3 12.1 40.8 23.3 20.3 38.8 55.8 65.1 2.5 10.7 15.9 20.0 17.9 12.0 43.6 2.1 8.1 8.3 7.1 21.8 7.8 5.9 7.2 4.4 6.7 89.5 6.1 85.7 2.8 5.8 8.5 109.5 6.6 4.3 8.0 1.6 73.4 10.7 94.8 9.3 23.5 20.3 5.2 15.0 53.6 0.5 3.8 49.9 5.4 15.9 9.2 10.1 8.3 19.5 1.3 21.7 6.5 71.0 7.0 31.6 0.8 59.7 4.5 18.3 71.0 45.5 5.3 4.4 10.2 5.4 5.6 1.7 0.5 5.3 18.6 5.0 11.8 3.0 29.2 0.0 0.0 32.8 0.0 1.3 0.0 0.0 31.9 1.3 0.0 0.4 2.2 0.1 25.7 3.0 0.1 16.5 76.8 87.9 96.9 86.3 60.2 89.8 105.5 111.9 93.9 95.1 159.3 65.1 8.3 0.0 0.0 12.1 7.3 36.2 21.3 76.5 49.5 212.8 16.7 13.8 3.2 1.5 20.4 9.2 171.0 63.9 2.5 0.2 9.8 3.4 0.5 13.3 9.8 8.8 4.8 9.2 5.4 0.6 9.4 29.6 3.6 2.2 1.3 4.8 4.6 1.3 56.4 144.7 13.5 0.1 12.2 71.6 54.7 0.5 14.9 78.0 8.8 6.5 49.4 142.6 3.1 3.5 0.9 1.8 0.1 9.1 2.0 13.1 0.0 2.8 12.1 209.7 0.0 4.0 12.3 2.6 3.6 68.3 66.1 108.9 2.2 0.2 0.1 29.7 ZNF57 ZNF424 ENSG00000171970 "Zinc finger protein 57" Q68EA5 19 2900898-2918473 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 25.9" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 30.7;Early spermatids: 95.2;Late spermatids: 64.7;Squamous epithelial cells: 36.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA061915 Approved Nucleoli NA NA "Cluster 35: T-regs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 34: Spermatids - Unknown function" Nucleoli "HPA061915: AB_2684635" "unprognostic (3.59e-2)" "unprognostic (1.53e-3)" "unprognostic (1.91e-2)" "unprognostic (8.86e-3)" "unprognostic (3.32e-2)" "unprognostic (3.07e-2)" "unprognostic (7.66e-2)" "prognostic favorable (6.26e-4)" "unprognostic (1.35e-1)" "unprognostic (4.04e-2)" "prognostic favorable (7.72e-4)" "unprognostic (2.34e-3)" "prognostic favorable (4.11e-9)" "unprognostic (6.26e-3)" "unprognostic (2.82e-2)" "unprognostic (7.35e-2)" "unprognostic (6.49e-3)" 2.8 2.5 1.8 2.0 1.9 4.0 6.4 8.0 3.2 5.5 1.3 8.2 7.2 2.6 3.6 9.1 4.2 1.9 3.0 2.1 1.8 4.6 3.4 3.3 2.8 2.0 1.9 3.7 4.0 4.0 2.9 4.8 2.2 3.9 9.2 4.2 4.4 3.5 1.7 18.3 6.2 1.8 1.5 2.4 11.7 25.9 2.1 3.8 4.6 2.4 3.3 3.3 7.9 2.1 7.4 3.4 4.7 6.8 4.4 3.8 7.8 3.1 2.5 4.9 5.1 7.1 2.9 6.3 3.8 2.5 7.1 8.5 7.5 10.7 6.0 0.0 3.9 3.7 3.8 9.6 3.3 0.0 6.5 3.0 11.8 4.3 9.3 4.0 3.7 14.8 6.6 0.1 3.8 7.5 9.7 4.1 3.0 8.7 5.9 8.9 14.1 1.4 6.7 12.0 2.3 3.5 4.6 8.4 3.1 6.6 5.2 6.1 2.9 3.3 3.2 7.7 4.4 1.3 7.4 3.0 2.7 1.0 2.7 0.0 2.4 1.1 4.4 4.2 3.6 3.2 4.8 4.5 2.6 3.6 5.4 4.8 0.9 5.1 2.3 2.5 5.5 3.0 1.8 1.9 8.0 3.2 2.1 1.8 2.0 1.9 2.2 1.5 2.1 2.1 2.2 0.0 5.3 1.6 0.8 21.4 20.3 8.1 30.7 2.2 3.4 3.8 4.1 1.5 7.8 0.0 6.2 4.4 1.9 13.5 3.9 3.1 95.2 7.4 3.4 2.1 0.0 0.4 2.6 2.3 3.7 2.8 7.7 12.3 0.0 2.3 1.4 1.9 2.3 1.7 2.7 7.4 8.2 1.0 2.7 64.7 2.5 1.3 5.4 0.0 1.7 1.9 0.0 1.0 1.5 1.5 9.5 3.0 0.2 5.4 19.8 3.4 4.2 2.8 0.0 0.8 2.5 5.7 9.7 36.6 28.7 6.6 1.7 3.1 8.1 9.7 ZNF750 "FLJ13841, Zfp750" ENSG00000141579 "Zinc finger protein 750" Q32MQ0 17 82829434-82840022 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Transcription, Transcription regulation" Activator "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 96.1;skin 1: 139.0;vagina: 51.7" "Cell type enhanced" "Detected in some" "Glandular and luminal cells: 33.3;Squamous epithelial cells: 156.8;Suprabasal keratinocytes: 41.1;Syncytiotrophoblasts: 68.1;Urothelial cells: 51.3" "Cancer enhanced" "Detected in many" "cervical cancer: 20.5;head and neck cancer: 24.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 18.3;hTCEpi: 7.2;MCF7: 5.4;SK-BR-3: 14.0" "Not detected" "Not detected" "HPA021573, HPA023012" Enhanced NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 28: BEWO - Transcription regulation" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA021573: AB_1859438, HPA023012: AB_1859439" "unprognostic (3.46e-3)" "unprognostic (1.94e-2)" "unprognostic (7.51e-2)" "unprognostic (2.63e-1)" "unprognostic (1.45e-1)" "unprognostic (9.73e-2)" "unprognostic (4.48e-2)" "unprognostic (6.55e-3)" "unprognostic (1.34e-1)" "unprognostic (4.33e-2)" "unprognostic (6.30e-3)" "unprognostic (1.23e-2)" "unprognostic (5.30e-3)" "unprognostic (3.04e-2)" "unprognostic (5.94e-2)" "unprognostic (2.04e-1)" "unprognostic (4.25e-2)" 0.5 0.1 0.8 0.0 1.2 0.1 5.1 0.5 0.9 25.0 0.0 0.1 0.1 0.2 4.1 96.1 0.6 0.2 0.6 0.6 0.2 0.4 0.1 2.0 0.0 1.0 0.3 0.1 0.2 2.2 2.9 3.9 1.0 3.3 0.0 0.0 33.6 2.7 12.0 139.0 0.1 0.0 0.2 0.1 0.2 0.4 0.6 5.1 3.5 0.0 14.7 4.9 51.7 2.3 0.1 0.0 0.0 0.0 0.0 0.0 18.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 3.3 1.2 1.0 0.0 14.0 0.0 1.7 2.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.2 0.5 0.9 0.6 0.2 1.0 0.3 1.0 0.2 0.6 2.3 0.6 0.0 8.2 0.0 0.0 5.2 14.3 19.6 9.1 0.0 7.4 5.0 0.4 0.0 21.2 0.0 0.0 23.1 0.0 0.0 0.0 0.0 2.4 27.1 3.3 0.9 0.0 0.0 0.4 0.0 1.9 0.3 0.0 33.3 0.0 0.0 0.0 0.0 2.1 0.0 0.3 0.0 10.2 0.0 0.3 0.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 7.6 0.0 0.1 14.2 0.0 0.0 0.1 1.5 0.0 0.2 156.8 41.1 68.1 0.2 0.0 0.0 51.3 ZSCAN22 "HKR2, ZNF50" ENSG00000182318 "Zinc finger and SCAN domain containing 22" P10073 19 58326994-58342332 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HEK 293: 14.7" "Low region specificity" "Detected in all" HPA006471 Uncertain Uncertain "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 15: Liver - Metabolism" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane, Cytosol" "Actin filaments" "HPA006471: AB_2221026" "unprognostic (5.55e-3)" "unprognostic (2.24e-1)" "unprognostic (6.56e-2)" "unprognostic (1.13e-1)" "unprognostic (1.93e-1)" "unprognostic (3.82e-2)" "unprognostic (2.47e-3)" "unprognostic (1.52e-1)" "unprognostic (2.91e-1)" "unprognostic (1.15e-1)" "unprognostic (2.15e-3)" "unprognostic (5.00e-2)" "unprognostic (7.59e-2)" "unprognostic (2.59e-2)" "unprognostic (1.74e-1)" "unprognostic (5.22e-3)" "unprognostic (1.07e-1)" 1.2 1.5 1.4 1.3 1.7 0.7 1.1 2.9 1.6 1.7 1.0 1.5 1.2 1.5 0.8 1.8 1.3 0.7 1.2 1.3 1.4 1.3 2.4 1.1 1.2 1.4 1.2 1.5 1.4 1.6 2.6 1.2 1.4 1.4 0.9 0.8 1.2 1.0 1.1 2.3 1.3 1.2 0.8 1.4 1.4 1.2 1.2 1.1 1.3 1.0 1.4 1.5 1.5 2.8 2.4 4.2 2.3 3.5 2.6 1.6 2.4 2.0 1.0 1.2 1.1 2.3 1.7 1.9 1.3 1.6 1.5 1.8 3.3 2.2 1.3 3.0 14.7 4.1 4.2 2.1 2.1 3.3 4.2 1.8 2.2 2.6 2.7 2.2 1.8 1.9 4.1 3.6 2.1 1.9 1.6 1.5 2.0 3.0 4.8 2.2 3.6 3.3 1.2 3.1 3.6 2.6 3.0 4.0 2.0 1.8 1.9 2.3 1.8 6.5 1.9 1.6 3.5 3.6 5.3 1.4 2.6 2.2 2.3 0.0 0.8 1.0 2.0 0.7 1.3 0.8 1.1 1.6 1.1 1.0 0.9 1.0 0.2 1.2 0.9 0.5 0.9 1.0 1.4 1.7 2.9 1.6 1.3 1.4 1.4 1.2 1.4 0.8 1.2 2.8 1.1 0.0 4.1 1.6 1.5 1.8 0.6 1.0 0.0 0.7 1.3 0.9 0.6 1.5 1.6 1.8 0.0 0.9 0.8 0.4 1.9 0.9 0.3 1.1 1.2 0.9 0.0 1.7 2.1 0.6 0.9 1.1 1.1 1.6 0.0 1.1 0.0 1.3 0.5 1.7 2.1 0.5 0.0 0.8 0.8 0.0 2.1 2.3 1.8 0.0 1.3 0.5 0.0 1.0 2.2 1.1 1.6 0.4 1.1 0.9 0.8 0.6 1.1 0.7 0.0 1.7 0.8 4.3 1.9 1.1 3.7 0.7 1.2 0.9 1.0 0.4