Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" AADACL4 ENSG00000204518 "Arylacetamide deacetylase like 4" Q5VUY2 1 12644085-12667076 "Predicted membrane proteins" Hydrolase "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (3.20e-1)" "unprognostic (1.89e-2)" 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.7 0.2 0.0 0.1 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ABCC11 MRP8 ENSG00000121270 "ATP binding cassette subfamily C member 11" Q96J66 16 48165773-48247568 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "breast: 46.4" "Cell type enhanced" "Detected in some" "Astrocytes: 3.3;Breast glandular cells: 4.4;Early spermatids: 3.3;Hepatocytes: 2.5;Late spermatids: 1.9;Spermatocytes: 4.0" "Cancer enriched" "Detected in some" 4 "breast cancer: 8.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "T-47d: 67.1" "Not detected" "Not detected" NA NA "Cluster 37: B-cells - Transcription" "Cluster 5: Breast - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (1.35e-1)" "unprognostic (3.47e-2)" "unprognostic (3.87e-2)" "unprognostic (2.47e-1)" "unprognostic (1.57e-1)" "unprognostic (6.03e-2)" "unprognostic (3.87e-2)" "unprognostic (1.56e-2)" "unprognostic (8.11e-2)" "unprognostic (2.39e-1)" "unprognostic (2.64e-1)" "unprognostic (7.05e-2)" "unprognostic (1.14e-1)" "unprognostic (2.21e-2)" "unprognostic (1.58e-1)" "unprognostic (1.13e-2)" "unprognostic (5.54e-4)" 0.1 0.0 0.2 0.0 0.3 0.1 46.4 0.4 0.3 0.0 0.2 0.0 0.3 0.1 0.0 0.0 0.5 0.1 0.0 0.2 0.2 0.0 1.6 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.2 3.6 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 2.4 0.3 0.0 0.3 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.4 0.6 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 16.0 0.1 0.0 67.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.4 0.3 0.2 0.2 0.2 0.2 0.2 0.1 0.3 0.3 0.1 0.0 0.5 3.3 0.2 0.0 0.0 0.0 0.0 0.4 4.4 0.9 0.6 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 3.3 0.3 0.1 0.1 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.0 2.5 0.0 0.0 0.6 0.0 0.0 0.3 0.0 1.9 0.0 0.2 0.0 0.0 0.0 0.5 0.0 1.0 1.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.2 0.0 4.0 0.4 0.5 0.0 0.3 0.2 0.1 0.0 0.1 ABHD12 "ABHD12A, BEM46L2, C20orf22, dJ965G21.2, DKFZP434P106" ENSG00000100997 "Abhydrolase domain containing 12, lysophospholipase" Q8N2K0 20 25294742-25390835 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Cataract, Deafness, Disease variant, Neuropathy, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 315.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026866 Uncertain NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 22: Non-specific - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA026866: AB_1844446" "prognostic unfavorable (3.81e-5)" "prognostic favorable (1.30e-5)" "unprognostic (1.32e-1)" "unprognostic (8.74e-2)" "unprognostic (3.67e-2)" "unprognostic (6.56e-2)" "prognostic unfavorable (7.18e-4)" "unprognostic (8.51e-2)" "unprognostic (7.91e-3)" "unprognostic (2.08e-1)" "unprognostic (4.08e-2)" "unprognostic (8.46e-2)" "unprognostic (1.36e-3)" "unprognostic (2.45e-1)" "unprognostic (4.65e-2)" "unprognostic (1.55e-1)" "unprognostic (8.11e-3)" 29.5 33.0 55.7 27.4 67.3 26.5 26.9 70.0 64.7 32.1 35.9 37.0 47.0 25.3 133.1 50.0 24.8 33.4 30.5 77.3 58.2 45.5 29.8 32.6 30.8 70.9 64.6 30.6 117.8 55.3 42.1 29.6 73.3 35.5 36.4 30.8 36.9 39.9 13.3 52.4 52.8 23.6 66.0 22.0 55.0 19.2 71.8 23.4 80.8 14.8 41.5 37.2 35.1 96.9 67.2 148.3 41.6 50.9 79.6 47.1 93.3 97.0 84.5 73.7 84.6 90.1 93.0 21.8 53.3 77.0 155.1 116.5 44.4 56.8 62.8 22.7 41.9 33.3 46.8 128.4 59.3 33.3 71.6 58.7 42.0 85.4 44.1 95.7 33.2 37.8 25.8 315.3 72.8 142.5 51.8 31.0 29.4 77.8 96.8 39.2 95.3 195.0 43.4 145.7 46.6 39.7 75.4 198.9 133.8 72.3 67.4 47.6 44.6 98.3 63.0 57.1 54.0 38.8 36.1 33.4 61.8 38.7 57.3 15.8 18.8 17.3 9.9 17.0 7.5 3.8 10.2 13.7 17.9 5.1 8.9 8.9 3.6 15.4 17.7 17.0 10.4 8.6 55.7 67.3 70.0 64.7 77.3 58.2 70.9 64.6 73.3 66.0 71.8 96.9 20.7 6.4 6.5 19.2 13.8 17.7 32.0 9.8 19.4 34.5 19.6 19.7 16.6 30.0 13.7 27.6 10.4 91.6 22.2 97.0 27.4 33.7 53.0 24.9 18.1 17.5 34.0 14.5 37.7 34.3 95.2 22.9 35.2 28.3 10.2 26.9 15.0 19.5 114.1 42.1 46.0 28.9 20.3 37.8 43.8 107.1 16.1 62.4 33.8 42.2 58.7 44.1 23.7 50.8 67.5 22.9 77.7 20.7 39.3 31.6 126.7 24.6 13.1 23.3 26.3 13.8 19.5 19.9 37.7 27.2 18.3 130.8 18.0 19.6 33.3 35.2 ABHD6 ENSG00000163686 "Abhydrolase domain containing 6, acylglycerol lipase" Q9BV23 3 58237532-58295693 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 64.9" "Cell type enhanced" "Detected in many" "Hepatocytes: 60.6;Oligodendrocytes: 88.6;Proximal enterocytes: 55.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017283, HPA073225" Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 45: Intestine - Brush border" "Cluster 3: HMC-1 - Innate immune response" "Cluster 2: Hepatocytes - Metabolism" Vesicles Nucleoplasm "HPA017283: AB_1844452, HPA073225: AB_2686583" "unprognostic (4.20e-2)" "unprognostic (7.92e-2)" "prognostic favorable (1.13e-4)" "unprognostic (2.35e-2)" "unprognostic (1.16e-2)" "unprognostic (3.00e-1)" "unprognostic (5.45e-2)" "unprognostic (1.15e-2)" "unprognostic (9.54e-2)" "unprognostic (1.11e-3)" "unprognostic (1.34e-2)" "unprognostic (1.94e-1)" "prognostic favorable (1.11e-11)" "unprognostic (1.94e-1)" "unprognostic (2.41e-1)" "unprognostic (2.72e-1)" "unprognostic (6.31e-2)" 12.2 12.9 24.0 6.4 33.9 0.9 8.9 34.1 32.4 4.4 19.4 12.7 39.5 6.1 14.7 6.4 9.1 5.8 5.7 31.6 26.9 35.6 64.9 8.5 8.0 31.7 32.3 5.0 2.7 8.9 16.6 6.4 31.7 5.5 11.1 9.2 4.0 14.3 4.6 25.5 52.3 9.2 28.8 35.0 12.9 3.9 35.5 5.5 9.1 5.4 7.6 5.8 5.9 49.8 3.5 12.0 1.8 8.5 23.2 4.2 21.2 8.9 8.1 9.2 12.5 6.9 4.8 6.6 0.8 4.7 28.5 9.9 8.3 3.9 8.4 11.3 4.2 5.7 8.1 9.7 7.8 1.7 28.1 3.9 18.4 8.8 3.8 10.6 5.0 10.6 6.8 15.0 7.2 2.6 11.7 0.7 6.1 28.5 27.3 4.2 3.8 14.8 14.5 4.8 10.8 4.4 9.9 5.1 19.0 3.7 3.6 4.5 5.8 6.6 7.0 16.6 10.8 4.2 13.5 0.3 17.1 16.9 9.3 0.0 2.2 1.7 1.6 7.4 1.5 3.6 0.9 1.9 3.7 2.5 0.9 1.1 0.0 0.7 5.2 5.4 1.2 1.0 24.0 33.9 34.1 32.4 31.6 26.9 31.7 32.3 31.7 28.8 35.5 49.8 27.1 0.0 1.8 11.4 13.6 8.7 3.0 2.7 6.2 13.3 2.1 1.5 5.6 5.7 4.9 3.7 4.2 2.0 7.7 11.2 1.9 3.0 1.0 9.8 7.9 14.1 0.0 5.7 33.6 1.9 0.9 2.9 7.7 1.5 11.4 10.1 21.4 60.6 8.9 15.2 34.3 4.0 0.0 16.7 20.0 0.7 6.8 12.1 3.6 11.2 11.5 11.2 6.2 37.7 88.6 1.9 1.4 8.2 2.0 1.8 55.1 17.4 13.8 3.3 0.0 2.9 3.9 0.5 2.2 6.9 24.6 0.5 5.1 16.0 5.8 2.0 AC007906.2 ENSG00000277639 "Novel protein" 16 53035690-53052873 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "choroid plexus: 86.7;fallopian tube: 77.8" "Group enriched" "Detected in some" 7 "Endometrial ciliated cells: 224.8;Respiratory ciliated cells: 209.9" "Cancer enhanced" "Detected in many" "ovarian cancer: 31.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 8.3;ASC TERT1: 7.0;BEWO: 11.6;HSkMC: 7.1;RPTEC TERT1: 7.5" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 28: BEWO - Transcription regulation" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (1.97e-2)" "unprognostic (8.34e-3)" "unprognostic (1.63e-1)" "unprognostic (5.38e-3)" "unprognostic (1.70e-1)" "unprognostic (5.75e-2)" "unprognostic (2.54e-1)" "unprognostic (1.06e-1)" "unprognostic (3.34e-1)" "unprognostic (2.25e-2)" "unprognostic (1.54e-2)" "unprognostic (5.02e-2)" "unprognostic (6.07e-2)" "unprognostic (5.68e-2)" "unprognostic (1.32e-1)" "unprognostic (1.02e-2)" "unprognostic (4.46e-3)" 1.0 0.3 1.6 0.4 1.1 0.0 6.0 1.0 0.4 11.2 86.7 4.5 0.6 2.8 1.4 9.0 77.8 10.5 1.4 2.9 2.0 16.5 1.3 9.5 0.1 6.5 10.4 0.3 11.6 0.3 0.3 1.5 3.9 9.4 5.1 0.0 3.5 2.7 1.0 4.7 0.4 0.8 3.4 0.0 0.9 0.2 2.5 0.8 0.3 1.0 1.2 6.8 2.6 1.6 0.1 2.5 4.1 2.1 8.3 7.0 11.6 1.2 0.9 0.1 0.0 0.3 1.7 0.2 2.1 1.7 0.8 0.7 0.0 1.6 0.5 0.2 0.1 0.0 0.1 0.6 1.6 0.0 1.8 7.1 6.2 2.3 0.7 2.3 1.7 0.1 0.1 0.1 3.8 0.1 0.1 0.0 4.6 0.4 0.6 1.0 0.0 0.0 7.5 1.6 0.2 0.0 0.3 0.0 0.1 3.4 0.8 0.1 2.0 2.7 2.7 0.1 0.0 0.0 0.0 0.0 3.3 0.4 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.1 1.0 0.4 2.9 2.0 6.5 10.4 3.9 3.4 2.5 1.6 0.1 0.0 5.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 20.7 12.7 0.0 0.0 30.3 25.8 0.0 0.1 0.5 0.0 5.9 4.9 0.0 224.8 1.7 0.8 0.0 0.0 0.0 0.0 0.3 3.2 0.0 7.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 7.4 209.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 ACAD8 ENSG00000151498 "Acyl-CoA dehydrogenase family member 8" Q9UKU7 11 134253548-134265855 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Branched-chain amino acid catabolism, Transcription, Transcription regulation" "Activator, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 59.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040689, HPA043903" Enhanced NA NA "Cluster 11: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" "HPA040689: AB_2677080, HPA043903: AB_2678724" "unprognostic (5.00e-2)" "unprognostic (2.40e-2)" "prognostic favorable (7.62e-4)" "unprognostic (7.57e-3)" "unprognostic (9.83e-2)" "prognostic favorable (6.19e-4)" "unprognostic (2.53e-1)" "prognostic favorable (2.38e-4)" "unprognostic (4.10e-2)" "unprognostic (2.84e-1)" "unprognostic (7.81e-3)" "unprognostic (2.16e-1)" "prognostic favorable (6.42e-10)" "unprognostic (1.08e-1)" "unprognostic (1.17e-2)" "unprognostic (4.02e-2)" "unprognostic (1.03e-2)" 11.0 18.1 13.9 3.5 14.2 6.8 11.3 14.3 15.4 7.5 18.7 11.6 11.3 6.3 12.6 9.6 9.4 5.2 27.2 14.7 14.3 31.6 24.8 7.8 5.0 14.3 14.1 6.9 16.7 12.4 6.5 4.8 13.8 20.5 10.9 5.0 12.6 7.5 32.5 14.3 8.4 8.3 14.5 8.6 12.6 6.3 14.8 8.5 27.7 39.2 8.9 8.4 6.9 14.8 5.9 5.9 11.8 17.6 20.2 11.5 13.5 11.3 14.0 14.7 10.3 16.2 10.8 14.2 21.1 11.7 15.5 6.0 14.6 14.3 10.2 13.0 4.7 29.4 5.8 11.3 17.0 16.5 18.3 13.8 4.4 14.8 4.5 13.3 16.3 20.8 13.8 7.0 12.4 7.5 12.2 18.1 17.0 49.8 9.7 9.8 11.9 8.5 20.1 17.5 3.7 11.7 19.5 14.8 7.3 11.9 31.0 15.0 11.3 7.1 7.5 6.2 11.2 7.8 3.8 12.7 7.2 15.4 11.2 36.2 13.4 23.1 11.8 13.5 11.5 11.6 11.1 11.7 12.7 9.2 13.0 11.7 12.1 31.5 12.9 10.8 15.1 12.3 13.9 14.2 14.3 15.4 14.7 14.3 14.3 14.1 13.8 14.5 14.8 14.8 11.7 3.2 12.2 15.3 8.8 6.0 4.7 23.5 7.4 11.2 17.5 11.9 24.6 4.3 19.7 18.4 14.6 19.7 14.0 20.0 52.8 12.1 5.3 8.2 11.8 9.7 3.6 12.0 21.5 11.9 10.6 9.8 10.2 8.5 3.8 15.7 10.8 36.7 12.9 15.2 16.0 14.3 48.8 14.2 6.9 6.1 11.5 10.0 28.4 13.1 12.7 11.8 9.2 12.1 15.8 12.6 15.8 10.1 14.6 5.9 17.4 59.8 20.1 17.1 6.6 8.7 9.6 22.4 17.3 10.9 7.7 8.3 10.5 36.0 14.9 5.3 ACO1 "IREB1, IREBP, IRP1" ENSG00000122729 "Aconitase 1" P21399 9 32384603-32454769 "Cancer-related genes, Citric acid cycle related proteins, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Tricarboxylic acid cycle" "Lyase, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 134.5" "Cell type enhanced" "Detected in all" "Hepatocytes: 194.4;Proximal tubular cells: 183.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 194.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019371, HPA024157" Enhanced Supported Mitochondria,Cytosol NA NA 10000000 "Cluster 38: Basophils - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Mitochondria, Cytosol" "HPA019371: AB_1844519, HPA024157: AB_1844520" "unprognostic (2.11e-1)" "unprognostic (5.61e-2)" "unprognostic (8.38e-2)" "unprognostic (9.12e-2)" "unprognostic (2.63e-1)" "unprognostic (3.12e-2)" "unprognostic (4.25e-3)" "unprognostic (2.61e-2)" "unprognostic (1.37e-1)" "unprognostic (1.19e-1)" "unprognostic (2.55e-1)" "unprognostic (3.08e-1)" "prognostic favorable (5.73e-5)" "unprognostic (2.54e-1)" "unprognostic (6.58e-2)" "unprognostic (1.65e-1)" "unprognostic (3.23e-2)" 96.6 50.5 15.2 16.1 15.4 3.5 50.1 14.6 15.3 19.8 19.1 23.7 48.6 19.2 30.2 15.4 14.6 15.6 36.3 14.0 16.2 89.2 134.5 20.3 8.8 15.8 15.8 17.4 37.6 22.8 13.1 16.1 14.9 21.9 20.6 12.9 16.6 19.1 25.1 12.0 35.8 22.9 15.3 9.3 28.7 17.6 16.9 13.6 34.5 37.8 7.1 24.4 13.7 14.1 37.5 33.7 25.7 40.7 194.5 104.8 11.6 69.3 169.1 31.2 24.5 36.0 11.4 7.4 21.6 73.1 84.9 5.1 51.3 66.3 62.3 23.8 13.8 54.7 33.4 39.3 97.4 5.1 21.2 91.7 20.1 80.4 56.1 95.6 81.7 28.4 20.0 15.7 89.9 9.9 29.5 26.4 26.9 23.3 35.5 22.8 38.0 7.8 118.9 34.1 3.3 10.5 71.9 2.8 7.6 27.1 16.7 13.5 89.2 112.5 38.2 38.2 18.2 7.8 15.5 14.7 78.7 18.2 10.2 33.2 11.3 3.3 9.2 11.3 8.0 5.6 6.2 6.9 9.3 5.0 8.1 8.2 1.2 6.7 10.0 4.3 3.9 8.4 15.2 15.4 14.6 15.3 14.0 16.2 15.8 15.8 14.9 15.3 16.9 14.1 16.3 3.2 25.7 43.8 6.7 4.5 7.9 11.9 9.1 21.4 17.8 7.4 45.5 38.6 11.7 23.9 22.9 50.8 6.2 26.4 19.6 19.0 8.7 10.0 30.7 18.7 4.9 11.6 24.6 41.0 22.1 29.7 39.3 13.9 2.5 17.1 15.7 194.4 15.1 33.7 46.5 27.7 10.2 14.8 6.7 6.9 23.6 15.6 7.2 20.6 8.6 25.7 8.2 22.1 24.1 19.4 23.7 23.3 7.2 10.1 56.1 183.4 10.7 14.3 19.7 30.5 22.2 9.8 19.4 10.3 5.4 53.5 7.5 22.2 34.6 8.7 ACOX2 "BRCACOX, BRCOX, THCCox" ENSG00000168306 "Acyl-CoA oxidase 2" Q99424 3 58505136-58537283 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 177.3" "Cell type enhanced" "Detected in many" "Hepatocytes: 89.0;Proximal enterocytes: 27.9;Proximal tubular cells: 51.0" "Cancer enhanced" "Detected in many" "liver cancer: 25.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 16.4;ASC TERT1: 25.9;fHDF/TERT166: 9.2;Hep G2: 10.8;HSkMC: 17.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA038280, HPA064845" Enhanced Approved Vesicles,Cytosol No No 29000 "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" Vesicles Cytosol "HPA038280: AB_10672623, HPA064845: AB_2685368" "unprognostic (6.62e-2)" "unprognostic (2.10e-1)" "unprognostic (1.08e-1)" "unprognostic (2.51e-2)" "unprognostic (8.34e-2)" "unprognostic (1.48e-2)" "unprognostic (8.67e-3)" "unprognostic (6.45e-2)" "unprognostic (1.00e-1)" "unprognostic (1.85e-1)" "unprognostic (1.70e-3)" "unprognostic (1.26e-2)" "unprognostic (1.68e-3)" "unprognostic (4.00e-3)" "unprognostic (2.34e-1)" "unprognostic (1.26e-1)" "unprognostic (5.63e-3)" 8.8 8.3 4.1 2.1 4.6 0.1 5.8 4.4 4.5 9.3 16.8 12.9 25.4 9.4 5.8 6.3 10.8 8.2 16.7 4.3 4.5 42.1 177.3 6.2 1.7 5.3 4.8 11.2 4.6 9.6 4.6 3.4 4.4 10.8 8.3 1.8 7.2 9.8 8.2 2.9 21.6 11.2 4.5 1.4 4.0 4.9 4.9 4.0 16.1 17.0 1.2 8.7 6.0 4.1 0.0 0.0 0.2 0.0 16.4 25.9 4.7 3.1 0.2 0.0 0.4 0.8 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.8 2.3 0.0 0.0 17.4 0.0 0.0 0.0 2.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 4.6 4.4 4.5 4.3 4.5 5.3 4.8 4.4 4.5 4.9 4.1 1.9 3.2 5.8 11.1 0.6 0.6 7.6 0.5 5.7 0.3 1.3 3.8 14.3 4.3 0.9 3.7 0.0 0.7 0.0 4.2 15.6 0.3 0.1 0.4 1.3 1.6 3.0 2.7 0.6 1.9 0.4 8.6 2.0 0.2 1.3 8.6 6.1 89.0 5.2 1.7 0.6 5.1 0.0 1.9 0.4 1.8 10.8 1.7 0.0 1.0 0.5 10.8 0.0 0.5 0.0 0.4 0.8 8.6 0.1 0.6 27.9 51.0 0.0 0.8 6.6 7.0 5.2 0.4 0.4 3.0 0.3 0.8 0.3 9.6 4.6 3.8 ACSL1 "ACS1, FACL1, FACL2, LACS, LACS1, LACS2" ENSG00000151726 "Acyl-CoA synthetase long chain family member 1" P33121 4 184755595-184826818 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 770.4;liver: 1319.0;skeletal muscle: 731.8" "Cell type enhanced" "Detected in many" "Early spermatids: 355.8;Hepatocytes: 1170.0;Late spermatids: 456.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 9 "neutrophil: 475.2" "Lineage enriched" "Detected in all" 9 "granulocytes: 475.2" "Cell line enhanced" "Detected in all" "ASC diff: 1124.0;ASC TERT1: 275.2;HSkMC: 609.5;RPTEC TERT1: 358.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011316, HPA011317, HPA011964" Enhanced Uncertain Vesicles NA NA 44000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "HPA011316: AB_1844536, HPA011317: , HPA011964: AB_1844537" "unprognostic (1.10e-2)" "unprognostic (3.19e-1)" "unprognostic (1.04e-1)" "unprognostic (1.64e-3)" "unprognostic (2.93e-2)" "unprognostic (1.21e-2)" "unprognostic (1.82e-3)" "unprognostic (2.75e-2)" "unprognostic (1.79e-1)" "unprognostic (5.89e-2)" "unprognostic (9.83e-2)" "unprognostic (3.15e-1)" "prognostic favorable (1.25e-5)" "unprognostic (2.77e-1)" "unprognostic (4.38e-2)" "unprognostic (6.25e-3)" "unprognostic (3.13e-2)" 770.4 43.3 32.5 94.8 43.9 337.9 316.7 45.2 70.2 62.1 60.7 34.0 32.4 41.6 78.2 66.0 50.6 36.2 172.7 34.4 39.1 218.7 1319.0 173.7 20.7 63.2 44.4 15.5 49.3 57.0 39.6 30.0 56.2 91.3 16.3 28.4 84.2 30.1 731.8 173.0 34.5 42.8 45.2 132.8 54.2 41.9 63.2 12.2 51.3 442.0 24.7 73.2 57.7 70.8 51.6 15.9 9.7 24.6 1124.0 275.2 8.3 29.1 13.8 16.1 11.2 3.9 14.0 22.2 3.0 32.8 38.4 29.7 43.1 17.8 13.3 107.1 17.7 16.6 13.1 40.5 183.4 41.9 37.2 609.5 140.7 13.6 67.1 27.6 21.1 3.6 7.5 59.4 77.0 26.9 3.1 55.1 2.0 32.5 23.3 8.0 8.6 27.0 358.4 135.9 36.3 35.1 25.4 70.8 86.5 3.9 26.9 39.8 25.1 13.8 16.8 34.5 8.7 24.5 13.5 8.9 45.6 56.3 22.4 16.5 54.7 17.7 3.3 30.9 2.8 3.3 2.3 1.5 13.1 3.4 2.5 2.2 475.2 4.4 23.0 2.4 4.9 20.8 32.5 43.9 45.2 70.2 34.4 39.1 63.2 44.4 56.2 45.2 63.2 70.8 7.5 25.6 121.0 6.5 15.7 21.0 16.0 14.0 5.2 6.6 49.7 10.3 119.1 25.8 33.5 31.3 18.8 10.2 7.1 4.3 93.9 4.6 355.8 9.8 25.0 9.8 0.0 34.1 15.2 12.8 2.2 19.4 36.2 24.6 24.1 1.5 18.2 1170.0 41.8 3.3 22.8 4.7 85.5 140.7 14.6 456.6 19.3 170.1 32.0 6.5 40.5 3.1 1.0 8.5 89.8 8.6 1.6 16.6 8.6 51.3 1.5 111.1 26.8 11.4 13.1 11.1 12.4 10.5 16.7 26.4 41.1 3.4 10.6 1.8 3.2 23.1 ACSM3 "SA, SAH" ENSG00000005187 "Acyl-CoA synthetase medium chain family member 3" Q53FZ2 16 20610243-20797581 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 85.1;liver: 178.5" "Cell type enhanced" "Detected in many" "Granulosa cells: 446.7;Hepatic stellate cells: 100.6;Proximal tubular cells: 136.0;Theca cells: 208.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 23.5" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 95.1;HMC-1: 381.7;K-562: 285.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA041013 Uncertain NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 3: HMC-1 - Innate immune response" "Cluster 40: Granulosa cells - Unknown function" "HPA041013: AB_10671693" "unprognostic (1.62e-4)" "unprognostic (1.30e-2)" "unprognostic (2.12e-2)" "unprognostic (9.50e-2)" "unprognostic (1.48e-1)" "unprognostic (2.32e-2)" "unprognostic (1.42e-2)" "unprognostic (2.20e-1)" "unprognostic (8.14e-3)" "prognostic favorable (1.97e-4)" "unprognostic (3.56e-2)" "unprognostic (1.95e-3)" "prognostic favorable (9.88e-6)" "unprognostic (1.27e-1)" "unprognostic (6.96e-2)" "unprognostic (1.06e-1)" "unprognostic (1.84e-2)" 4.5 3.2 1.7 2.4 1.6 15.3 60.2 2.1 3.1 10.3 1.9 26.4 7.7 19.9 5.7 3.2 26.8 10.4 8.6 1.7 0.8 85.1 178.5 8.1 3.1 3.1 2.7 74.8 30.4 15.2 0.9 2.5 2.5 22.0 25.6 1.0 4.8 6.9 0.8 4.3 8.2 5.1 1.0 1.9 28.1 5.9 2.2 2.8 2.8 1.0 2.9 4.9 5.2 5.3 1.0 12.4 2.3 0.7 3.9 2.3 1.5 0.2 1.3 0.3 1.0 1.0 18.2 1.6 20.1 0.4 0.7 1.6 0.2 2.1 1.6 4.5 6.6 95.1 0.2 7.7 1.3 10.9 381.7 3.7 2.2 0.5 1.4 1.9 0.2 0.7 285.1 15.3 0.1 1.5 0.7 3.5 0.7 14.5 3.8 3.1 0.1 20.3 18.3 1.1 0.8 0.7 0.4 5.4 0.3 0.8 6.1 0.9 1.3 1.2 1.2 0.9 0.7 21.9 18.6 1.2 1.2 7.5 0.5 2.6 2.0 23.5 3.6 1.2 4.2 1.6 4.5 3.3 0.2 2.8 6.9 8.2 0.5 2.3 4.0 2.3 5.6 2.9 1.7 1.6 2.1 3.1 1.7 0.8 3.1 2.7 2.5 1.0 2.2 5.3 0.3 3.2 31.3 1.0 16.5 2.8 34.6 1.5 8.0 0.0 6.3 6.1 3.2 20.0 1.7 12.9 0.0 19.1 1.5 7.0 84.1 84.8 25.0 14.0 4.3 3.4 2.4 25.4 0.3 12.5 2.1 23.7 8.6 32.8 0.0 446.7 100.6 38.2 3.2 0.0 0.3 11.8 0.0 5.4 1.7 12.3 27.7 3.4 0.0 0.0 3.1 0.0 4.1 0.0 0.1 8.9 20.3 12.8 1.0 14.5 4.7 136.0 1.5 0.0 0.0 0.4 52.7 6.9 2.2 3.8 1.8 19.2 4.3 208.3 23.0 11.3 ACTA1 "ACTA, NEM3" ENSG00000143632 "Actin alpha 1, skeletal muscle" P68133 1 229431245-229434098 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Muscle protein" "Disease variant, Nemaline myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "skeletal muscle: 133409.0" "Group enriched" "Detected in some" 36 "Cardiomyocytes: 1901.9;Skeletal myocytes: 1541.2" "Group enriched" "Detected in many" 18 "head and neck cancer: 133.1;prostate cancer: 34.7" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 22 "BEWO: 469.2" "Low region specificity" "Detected in all" "CAB000045, HPA041264, HPA041271" Enhanced NA NA 2800000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 28: BEWO - Transcription regulation" "Cluster 37: Myocytes - Muscle contraction" "CAB000045: AB_2242301, HPA041264: AB_2677383, HPA041271: AB_2677386" "unprognostic (5.59e-2)" "unprognostic (1.60e-2)" "unprognostic (1.77e-1)" "unprognostic (3.07e-4)" "unprognostic (5.75e-3)" "unprognostic (3.84e-3)" "unprognostic (1.86e-1)" "unprognostic (7.61e-2)" "unprognostic (1.32e-1)" "unprognostic (2.24e-1)" "unprognostic (2.64e-3)" "unprognostic (2.50e-1)" "unprognostic (1.56e-3)" "unprognostic (9.40e-4)" "unprognostic (2.61e-1)" "unprognostic (1.58e-2)" "unprognostic (1.01e-1)" 15.3 3.8 1.2 1.6 1.2 0.3 19.8 1.8 2.8 1.2 0.4 8.8 0.3 3.0 0.0 604.6 0.6 1.6 6656.6 1.2 3.5 2.6 7.3 7.6 2.2 0.9 1.1 4.6 7.3 0.0 4.7 1.2 0.8 164.8 0.0 0.1 591.0 0.7 133409.0 36.0 5.3 66.3 0.7 3.0 5.1 2.5 1.4 3.1 14.5 20867.7 0.9 3.0 5.4 1.0 0.2 0.2 0.1 0.4 0.0 0.1 469.2 0.0 0.0 0.3 0.1 0.5 0.1 0.3 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.1 1.4 0.2 0.5 21.5 0.0 0.5 0.7 20.8 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.3 0.1 0.0 0.2 0.5 0.2 0.0 0.2 0.3 0.3 0.2 0.0 0.3 0.2 0.5 0.2 4.3 0.1 0.0 0.3 0.4 0.6 0.3 0.2 0.5 0.5 0.6 1.0 0.3 0.3 0.6 0.3 18.3 16.5 34.2 11.5 25.4 8.4 6.7 9.4 11.2 23.6 6.4 7.2 11.5 18.8 8.2 24.1 7.5 15.7 45.4 1.2 1.2 1.8 2.8 1.2 3.5 0.9 1.1 0.8 0.7 1.4 1.0 0.2 0.0 0.0 0.3 0.1 0.5 0.4 0.8 0.0 0.8 0.3 2.2 1901.9 0.0 0.1 0.0 4.2 1.7 0.0 0.0 0.0 1.9 0.4 0.1 0.4 38.1 0.0 0.0 0.6 0.0 3.3 43.6 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.5 0.1 0.0 0.0 2.1 0.3 0.0 9.7 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.4 0.0 0.4 0.3 0.3 0.0 0.0 0.0 0.0 0.0 1541.2 46.6 1.1 0.2 0.7 0.4 0.3 8.2 0.1 0.1 0.2 ACTA2 ACTSA ENSG00000107796 "Actin alpha 2, smooth muscle" P62736 10 88935074-88991339 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Muscle protein" "Aortic aneurysm, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "endometrium 1: 6678.8;seminal vesicle: 5920.3;smooth muscle: 8099.9" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 1007.7;Peritubular cells: 5290.7;Sertoli cells: 3030.6;Smooth muscle cells: 2394.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 58.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 390.6;fHDF/TERT166: 641.1;HHSteC: 625.8;HSkMC: 345.1;hTERT-RPE1: 743.4;SuSa: 296.8" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "midbrain: 101.0" "CAB000002, CAB003761, CAB013531, HPA041264, HPA041271" Enhanced Supported "Actin filaments" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Actin filaments" "CAB000002: AB_2223500, CAB003761: AB_562031, CAB013531: , HPA041264: AB_2677383, HPA041271: AB_2677386" "unprognostic (7.05e-2)" "unprognostic (2.54e-1)" "unprognostic (2.30e-3)" "unprognostic (3.18e-2)" "unprognostic (3.33e-2)" "unprognostic (6.19e-2)" "unprognostic (2.36e-2)" "unprognostic (1.71e-2)" "unprognostic (4.25e-2)" "unprognostic (1.20e-1)" "unprognostic (1.44e-1)" "unprognostic (6.93e-2)" "prognostic unfavorable (1.37e-8)" "unprognostic (1.87e-3)" "unprognostic (2.30e-1)" "unprognostic (7.91e-2)" "unprognostic (2.09e-3)" 1035.2 241.6 54.0 728.1 61.4 3.9 838.4 52.7 121.1 2000.3 61.4 2755.1 248.9 6678.8 1360.1 1509.9 3104.3 906.1 1069.2 53.4 54.6 312.2 161.8 732.8 173.7 59.0 55.9 798.0 91.4 80.6 60.8 771.3 55.3 2642.8 866.4 8.2 414.7 5920.3 202.1 355.7 701.6 8099.9 54.1 452.1 1427.1 263.9 56.1 56.5 312.0 214.0 48.4 3002.5 1367.0 52.9 3.9 19.0 49.3 102.7 198.1 390.6 9.5 109.8 136.8 11.9 45.4 0.0 8.8 7.2 11.5 641.1 8.6 1.4 1.8 25.4 11.3 60.6 11.3 0.4 5.6 119.3 625.8 0.8 3.2 345.1 44.9 73.9 28.5 743.4 11.3 3.0 0.0 7.1 128.8 10.8 1.0 28.3 2.5 0.2 1.2 1.4 0.2 4.6 27.1 5.0 0.7 7.6 10.2 7.9 1.0 296.8 32.4 1.0 27.9 24.0 4.0 30.2 9.3 21.1 1.6 0.6 29.6 10.2 26.1 28.1 12.3 17.5 17.6 8.7 13.8 6.0 14.1 19.8 10.8 1.8 1.5 10.7 11.1 4.0 14.2 0.4 58.7 10.7 54.0 61.4 52.7 121.1 53.4 54.6 59.0 55.9 55.3 54.1 56.1 52.9 65.4 9.6 6.1 5.5 4.4 43.2 23.4 16.5 22.8 1.1 22.7 1007.7 25.1 2.8 5.2 0.0 6.2 16.3 7.3 1.9 1.9 1.8 11.1 11.1 225.4 41.1 0.0 4.0 3.6 0.9 16.8 316.3 10.7 8.2 5.7 448.9 474.0 4.6 37.7 0.0 1.1 2.7 4.1 5.4 67.6 48.8 141.4 12.6 55.2 61.8 4.2 13.4 4.1 1.0 0.3 2.0 3.0 5290.7 3.7 17.5 3.4 9.5 10.9 1.4 3030.6 72.0 2394.6 4.0 13.8 11.1 40.5 23.7 16.5 36.0 5.7 10.4 ACTC1 "ACTC, CMD1R" ENSG00000159251 "Actin alpha cardiac muscle 1" P68032 15 34790230-34795549 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Muscle protein" "Atrial septal defect, Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 21 "heart muscle: 11410.0" "Cell type enriched" "Detected in some" 30 "Cardiomyocytes: 9746.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 20.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 1131.8;LHCN-M2: 4544.5;RH-30: 2053.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB037330, HPA041264, HPA041271" Enhanced NA NA 2400000000 "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" "CAB037330: , HPA041264: AB_2677383, HPA041271: AB_2677386" "unprognostic (8.18e-3)" "unprognostic (3.74e-2)" "unprognostic (4.82e-3)" "unprognostic (1.19e-2)" "unprognostic (3.04e-2)" "prognostic unfavorable (3.72e-5)" "unprognostic (3.26e-1)" "unprognostic (2.05e-3)" "unprognostic (2.26e-1)" "unprognostic (7.98e-2)" "unprognostic (1.14e-2)" "unprognostic (2.10e-3)" "unprognostic (5.68e-4)" "unprognostic (8.79e-2)" "unprognostic (1.65e-1)" "unprognostic (1.48e-2)" "prognostic unfavorable (9.32e-4)" 51.1 1.8 1.9 24.7 1.7 0.0 11.9 2.1 2.6 8.6 1.3 4.0 0.8 6.9 1.1 22.8 1.6 11.8 11410.0 1.9 2.8 1.5 0.6 3.9 2.6 2.7 2.8 3.2 12.9 1.0 2.2 8.9 3.0 73.0 3.6 31.6 11.5 538.1 135.2 4.6 0.6 8.8 1.4 1.3 9.3 0.5 4.0 11.3 2.4 195.0 0.2 439.6 16.1 1.5 0.0 0.2 0.1 0.0 0.2 3.3 0.2 2.2 0.7 5.2 1.3 0.0 0.0 0.0 1.3 1131.8 0.2 0.0 0.4 0.0 1.3 0.0 0.0 0.1 23.9 0.0 0.1 1.4 0.0 457.2 0.0 0.2 0.1 0.3 0.1 0.0 0.0 0.0 4544.5 0.0 0.0 0.0 3.8 0.0 0.0 0.0 2053.3 0.0 0.0 0.0 0.1 0.1 4.0 0.0 0.0 31.2 0.0 0.0 0.0 0.2 0.3 0.0 0.2 0.0 0.0 0.2 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 1.7 2.1 2.6 1.9 2.8 2.7 2.8 3.0 1.4 4.0 1.5 0.0 0.0 0.0 0.3 0.0 0.5 0.3 0.0 0.0 11.9 0.1 0.0 9746.1 0.0 0.0 0.0 20.9 0.1 0.0 0.0 1.9 0.0 5.0 0.0 0.1 69.2 0.0 0.0 0.2 0.2 4.3 315.2 0.0 0.0 0.0 0.1 0.4 0.4 0.1 0.0 0.4 0.0 0.0 0.0 0.0 1.9 0.0 0.2 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 7.2 0.0 63.4 86.5 1.0 0.7 0.0 0.4 0.3 0.1 0.1 0.0 0.0 ACVR2A "ACTRII, ACVR2" ENSG00000121989 "Activin A receptor type 2A" P27037 2 147844517-147930826 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 62.5;Inhibitory neurons: 63.4;Oligodendrocyte precursor cells: 84.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HHSteC: 26.3;RH-30: 23.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046997 Approved Approved Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA046997: AB_10970077" "unprognostic (4.55e-2)" "unprognostic (2.26e-2)" "unprognostic (2.09e-1)" "unprognostic (7.34e-3)" "unprognostic (2.75e-1)" "unprognostic (1.17e-1)" "unprognostic (4.41e-3)" "unprognostic (8.73e-3)" "unprognostic (1.30e-2)" "unprognostic (3.61e-1)" "unprognostic (1.34e-2)" "unprognostic (1.52e-1)" "prognostic favorable (1.62e-4)" "unprognostic (1.16e-1)" "unprognostic (1.40e-1)" "unprognostic (3.95e-1)" "unprognostic (3.99e-2)" 7.3 4.0 6.2 4.6 7.4 3.3 7.0 10.8 6.4 5.4 1.0 6.3 7.7 5.2 6.6 7.2 4.5 7.7 3.7 7.5 7.5 5.6 7.4 4.6 3.1 2.6 4.5 4.5 4.4 4.3 3.9 7.7 3.9 6.8 6.5 8.3 7.5 5.2 17.5 19.5 9.3 7.0 3.8 4.0 6.8 6.4 8.6 2.3 6.7 6.3 3.9 7.4 7.4 4.6 1.8 2.1 13.2 5.0 7.3 4.7 5.4 4.1 5.0 6.9 12.0 5.8 8.1 0.1 3.6 6.7 2.5 6.2 12.0 6.1 8.8 1.4 7.3 0.9 3.6 10.2 26.3 1.0 0.9 8.1 7.3 4.5 8.9 5.2 5.3 1.6 2.0 3.5 4.7 4.8 0.4 0.8 14.9 5.5 3.6 0.2 23.3 1.3 5.6 11.5 13.0 7.3 3.5 4.2 5.4 5.6 2.5 1.4 4.1 6.4 7.5 6.1 2.9 1.0 0.3 2.4 3.9 0.5 5.2 0.2 1.7 0.2 0.6 2.0 0.2 0.1 2.4 1.1 1.3 0.3 1.5 0.3 0.0 4.8 2.0 1.7 0.2 0.7 6.2 7.4 10.8 6.4 7.5 7.5 2.6 4.5 3.9 3.8 8.6 4.6 13.7 6.4 7.0 26.8 1.5 29.7 6.9 9.5 13.1 15.4 6.8 12.4 7.9 17.2 10.7 7.3 14.6 4.9 6.0 16.5 1.9 6.3 5.3 6.4 12.2 11.9 9.0 0.0 62.5 6.3 2.5 17.4 6.6 5.7 0.0 2.2 11.7 12.1 5.4 11.8 63.4 12.9 8.2 7.3 18.9 2.1 9.9 5.7 10.6 33.7 7.2 3.3 6.2 84.9 34.1 7.6 10.0 11.3 5.2 7.7 23.7 5.8 10.2 9.4 32.9 8.3 10.9 18.2 14.1 14.4 29.8 5.3 5.9 2.9 11.7 11.8 ACY1 ENSG00000243989 "Aminoacylase 1" Q03154 3 51983340-51989197 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 9 "intestine: 181.5;kidney: 449.9;liver: 274.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 31.6;Gastric mucus-secreting cells: 32.6;Proximal enterocytes: 144.8;Proximal tubular cells: 92.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 128.0" "CAB003695, HPA036174, HPA036175" Enhanced NA NA 23000000 "Cluster 27: Non-specific - Gene expression" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB003695: AB_425286, HPA036174: AB_2674988, HPA036175: AB_2674989" "unprognostic (4.28e-2)" "unprognostic (1.89e-1)" "unprognostic (2.10e-1)" "unprognostic (2.48e-3)" "unprognostic (3.15e-1)" "unprognostic (6.51e-2)" "unprognostic (2.82e-2)" "unprognostic (1.47e-1)" "unprognostic (1.05e-2)" "unprognostic (6.08e-2)" "unprognostic (2.36e-2)" "unprognostic (2.70e-2)" "prognostic favorable (2.93e-4)" "unprognostic (3.57e-1)" "unprognostic (3.75e-1)" "unprognostic (7.88e-2)" "prognostic favorable (6.77e-4)" 19.2 24.0 5.6 7.3 5.7 8.8 20.7 6.4 7.3 13.9 11.6 30.6 181.5 4.3 21.8 10.7 13.0 10.7 14.5 5.1 6.0 449.9 274.9 9.2 7.2 6.5 5.9 4.8 8.7 28.2 4.7 9.7 6.6 14.3 30.5 1.9 16.4 11.1 20.2 8.2 138.2 6.9 6.7 8.1 23.6 3.2 6.1 5.1 21.0 34.6 9.2 12.5 7.1 6.6 15.9 26.2 13.2 34.1 28.9 39.4 40.5 12.6 28.2 29.4 14.9 41.2 67.9 7.2 12.2 22.0 13.2 20.0 14.7 81.2 11.5 21.8 10.7 25.3 13.9 128.0 49.7 19.8 21.0 48.0 67.2 25.4 69.1 25.8 11.5 14.6 47.1 23.9 29.9 35.2 0.6 38.9 23.4 92.1 39.3 8.0 14.1 63.5 74.5 50.8 16.9 18.2 12.6 62.6 29.5 7.5 42.3 27.9 7.1 22.0 21.9 24.8 18.8 61.7 16.9 12.1 28.1 42.9 29.0 9.1 15.7 0.4 10.7 15.1 5.7 7.4 2.6 4.5 21.2 6.1 4.1 4.7 0.0 20.4 6.4 2.8 3.8 9.7 5.6 5.7 6.4 7.3 5.1 6.0 6.5 5.9 6.6 6.7 6.1 6.6 0.5 3.2 3.2 0.0 4.9 0.6 1.0 1.9 17.1 0.2 2.7 1.3 0.2 1.5 2.5 5.5 0.0 3.9 0.3 31.6 9.8 16.6 0.2 0.2 0.9 0.9 2.4 15.8 0.0 8.3 4.5 4.3 32.6 0.6 7.0 0.2 1.1 13.1 1.9 0.0 0.0 11.2 4.1 1.9 0.3 0.8 0.6 4.2 0.0 0.0 9.3 0.8 1.0 0.0 0.0 16.4 23.3 0.0 14.9 0.6 144.8 92.0 1.7 1.1 0.0 0.6 2.0 0.1 0.2 18.5 0.4 4.1 2.6 1.0 14.5 0.4 ADCY8 "AC8, ADCY3, HBAC1" ENSG00000155897 "Adenylate cyclase 8" P40145 8 130780301-131040909 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 29.4;epididymis: 22.8" "Group enriched" "Detected in some" 5 "Astrocytes: 151.8;Inhibitory neurons: 250.9;Oligodendrocyte precursor cells: 138.7" "Group enriched" "Detected in some" 5 "glioma: 6.0;ovarian cancer: 1.8;thyroid cancer: 1.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 5.0;GAMG: 8.2;U-138 MG: 17.6;U-87 MG: 34.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018652, HPA024291" Supported NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB018652: AB_633654, HPA024291: AB_1844597" "unprognostic (5.59e-3)" "unprognostic (3.10e-1)" "unprognostic (1.82e-1)" "unprognostic (1.09e-1)" "unprognostic (2.78e-2)" "unprognostic (1.74e-1)" "unprognostic (1.05e-1)" "unprognostic (8.22e-3)" "unprognostic (4.91e-2)" "unprognostic (7.39e-3)" "unprognostic (1.92e-1)" "unprognostic (2.44e-2)" "unprognostic (6.67e-2)" 0.0 0.0 17.0 0.0 13.4 0.0 0.5 19.7 9.6 0.4 1.7 0.0 0.0 0.0 22.8 0.0 3.9 0.0 0.0 11.9 14.0 0.2 0.0 1.2 0.0 17.2 22.6 0.0 0.0 0.0 0.0 0.0 15.2 0.0 0.0 3.1 1.1 1.4 0.1 2.1 0.0 0.5 25.9 0.0 0.1 0.5 29.4 0.0 0.0 0.0 0.0 0.0 0.0 23.3 0.0 0.0 0.0 0.1 1.3 5.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 17.6 0.4 0.0 0.0 0.0 0.0 0.0 34.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.0 13.4 19.7 9.6 11.9 14.0 17.2 22.6 15.2 25.9 29.4 23.3 0.0 0.0 1.5 151.8 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.0 0.0 0.0 0.0 0.0 32.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 250.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 8.4 0.0 0.1 0.0 138.7 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ADGRF2 "GPR111, hGPCR35, PGR20" ENSG00000164393 "Adhesion G protein-coupled receptor F2" Q8IZF7 6 47656436-47697797 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "fallopian tube: 1.0;skin 1: 2.1" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 1.1;Early spermatids: 1.0;Endometrial ciliated cells: 1.6;Excitatory neurons: 1.2;Glandular and luminal cells: 1.3;Squamous epithelial cells: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA035507 Uncertain NA NA "Cluster 31: Skin - Epidermis development" "Cluster 44: Endometrium - Transcription" "HPA035507: AB_10601809" "unprognostic (1.79e-2)" "unprognostic (1.10e-1)" "unprognostic (5.16e-2)" "unprognostic (3.74e-2)" "unprognostic (5.95e-1)" "unprognostic (1.59e-1)" "unprognostic (1.53e-1)" "unprognostic (1.38e-1)" "unprognostic (1.25e-1)" "unprognostic (2.51e-4)" "unprognostic (3.05e-2)" "unprognostic (3.86e-2)" "unprognostic (1.20e-1)" "unprognostic (2.24e-1)" "unprognostic (7.99e-2)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 2.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 1.6 0.1 0.4 0.0 0.0 1.2 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.1 ADIPOQ "ACDC, ACRP30, adiponectin, apM1, GBP28" ENSG00000181092 "Adiponectin, C1Q and collagen domain containing" Q15848 3 186842704-186858463 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters" Hormone "Diabetes mellitus, Disease variant, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 28 "adipose tissue: 898.8;breast: 248.9" "Cell type enhanced" "Detected in single" "Distal tubular cells: 1.9" "Group enriched" "Detected in some" 8 "breast cancer: 6.5;pancreatic cancer: 1.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 672 "ASC diff: 312.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB046467, HPA051767" Uncertain "Secreted to blood" NA NA 8360000000 910000000 "Cluster 17: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB046467: AB_1078104, HPA051767: AB_2681598" "unprognostic (1.76e-2)" "unprognostic (1.53e-1)" "unprognostic (2.20e-2)" "unprognostic (6.99e-3)" "unprognostic (1.87e-1)" 898.8 8.9 0.1 2.4 0.1 0.2 248.9 0.2 0.1 0.0 0.0 7.7 0.1 0.1 0.0 1.2 0.1 7.6 6.5 0.0 0.0 0.8 0.1 0.1 1.3 0.1 0.0 0.0 6.2 0.1 0.1 0.0 0.1 0.3 6.1 0.1 18.8 0.0 2.3 6.6 8.5 1.2 0.0 0.0 3.9 0.1 0.1 2.2 2.9 20.2 0.0 2.4 0.9 0.3 0.0 0.0 0.0 0.1 312.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.2 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ADORA3 AD026 ENSG00000282608 "Adenosine A3 receptor" P0DMS8 1 111499429-111503633 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 21.8" "Cell type enhanced" "Detected in some" "Hofbauer cells: 17.9;Kupffer cells: 79.2;Late spermatids: 18.2;Macrophages: 26.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 40 "eosinophil: 601.6" "Lineage enriched" "Detected in many" 40 "granulocytes: 601.6" "Cell line enriched" "Detected in some" 9 "HMC-1: 108.1" "Low region specificity" "Detected in many" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" 4.5 15.0 8.9 4.3 9.2 0.2 5.5 10.6 14.6 4.4 8.8 6.6 4.5 1.9 0.2 2.5 3.6 5.8 3.4 8.8 12.3 1.6 3.3 3.5 6.4 16.1 11.1 1.8 1.8 3.1 2.6 2.8 14.9 2.4 5.1 1.0 2.8 2.4 0.5 0.9 9.4 4.8 13.5 4.3 3.0 1.2 16.9 3.5 1.4 1.0 2.7 4.3 1.7 21.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.8 0.0 0.0 0.0 0.0 108.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 12.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 10.0 8.1 601.6 0.0 5.6 0.1 0.2 0.0 0.0 15.0 0.1 0.1 0.1 2.0 0.1 2.1 3.0 0.0 2.5 8.9 9.2 10.6 14.6 8.8 12.3 16.1 11.1 14.9 13.5 16.9 21.8 0.2 0.0 0.0 0.0 1.0 0.3 0.0 0.0 0.0 0.1 0.1 0.6 0.4 0.0 0.0 0.0 0.0 0.1 1.4 0.1 0.0 0.0 7.3 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.0 0.0 1.8 0.2 17.9 0.0 0.0 0.0 0.0 79.2 4.4 18.2 0.3 26.3 0.0 0.0 2.2 0.1 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.7 0.0 0.2 0.0 0.2 0.2 0.4 0.3 0.1 0.4 0.0 1.6 0.0 0.0 0.1 ADPRS "ADPRHL2, ARH3, FLJ20446" ENSG00000116863 "ADP-ribosylserine hydrolase" Q9NX46 1 36088892-36093932 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" Hydrolase "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 6 "Cytotrophoblasts: 79.2;Extravillous trophoblasts: 40.7;Hofbauer cells: 51.6;Syncytiotrophoblasts: 70.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026641, HPA027104, HPA027141" Approved Enhanced Nucleoplasm "Intracellular and membrane" NA NA 54000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "HPA026641: , HPA027104: AB_10601330, HPA027141: AB_1844619" "unprognostic (3.22e-3)" "unprognostic (5.10e-2)" "unprognostic (2.95e-2)" "unprognostic (1.61e-2)" "unprognostic (5.98e-2)" "unprognostic (2.09e-1)" "prognostic unfavorable (2.10e-7)" "unprognostic (3.71e-2)" "unprognostic (2.63e-1)" "unprognostic (5.34e-2)" "unprognostic (3.17e-2)" "unprognostic (7.80e-2)" "prognostic unfavorable (3.71e-4)" "unprognostic (4.37e-2)" "unprognostic (9.31e-2)" "unprognostic (3.65e-2)" "unprognostic (4.74e-2)" 19.0 36.7 28.4 16.0 30.0 19.7 18.5 31.3 30.3 20.7 33.4 19.6 15.6 17.6 15.0 36.1 33.5 13.3 20.7 28.6 29.1 27.7 22.4 20.6 21.5 32.5 29.7 19.7 17.9 17.6 17.7 20.8 31.2 19.9 12.4 9.1 20.9 16.3 34.4 34.1 16.8 16.4 31.9 23.1 17.6 28.7 29.7 20.9 19.4 21.8 20.2 21.3 22.2 33.9 54.3 22.4 26.2 37.2 23.6 17.1 37.3 39.4 32.9 62.1 60.9 26.8 47.7 38.4 37.5 39.5 32.0 32.9 33.4 60.5 37.0 27.7 41.8 34.9 27.0 36.3 44.4 40.2 19.9 20.3 45.4 56.5 24.5 47.2 39.9 36.2 30.8 30.9 29.6 26.0 40.9 60.5 56.5 31.8 46.0 32.9 27.6 38.8 56.5 43.8 32.1 50.8 28.9 29.9 65.9 34.4 30.9 34.3 27.6 35.7 37.0 50.1 53.0 39.8 41.2 34.2 51.7 39.6 22.4 40.6 58.3 65.8 43.4 74.1 41.5 43.5 47.6 50.8 71.4 51.5 47.7 40.3 57.1 47.9 77.7 44.8 43.4 57.8 28.4 30.0 31.3 30.3 28.6 29.1 32.5 29.7 31.2 31.9 29.7 33.9 3.5 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.5 0.0 0.0 0.0 0.0 79.2 6.2 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 40.7 6.4 0.0 0.0 0.0 0.0 0.0 0.0 51.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 70.6 1.3 0.0 0.0 0.0 AFTPH "FLJ20080, FLJ23793, MGC33965, Nbla10388" ENSG00000119844 Aftiphilin Q6ULP2 2 64524305-64593005 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034990, HPA034991" Approved Supported "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 59: Non-specific - Transcription" Cytosol "Golgi apparatus, Vesicles" "HPA034990: AB_2674398, HPA034991: AB_10603577" "unprognostic (7.30e-2)" "unprognostic (4.72e-2)" "unprognostic (9.16e-2)" "unprognostic (8.54e-2)" "unprognostic (3.24e-1)" "unprognostic (4.25e-2)" "unprognostic (2.54e-2)" "unprognostic (1.75e-2)" "unprognostic (1.52e-1)" "unprognostic (8.44e-2)" "unprognostic (3.42e-2)" "unprognostic (4.65e-2)" "prognostic favorable (2.37e-5)" "prognostic favorable (8.44e-4)" "unprognostic (3.12e-1)" "unprognostic (1.74e-1)" "prognostic favorable (1.83e-4)" 15.9 20.2 24.6 21.1 24.9 21.3 32.4 31.2 38.4 22.5 28.3 30.5 23.1 18.8 43.7 29.6 22.9 21.9 12.0 25.3 25.6 56.1 33.6 21.9 37.2 24.6 24.6 19.3 31.6 38.0 25.1 15.0 24.5 34.5 33.7 36.8 28.9 18.6 15.4 33.2 24.5 17.3 24.8 26.4 33.7 24.6 25.4 29.3 25.3 12.9 41.4 25.5 22.4 26.2 29.8 19.3 14.1 17.1 17.8 15.1 23.4 16.7 24.9 26.9 20.1 22.4 21.9 43.9 16.0 20.7 31.1 23.5 24.6 23.3 34.8 42.8 13.5 21.0 12.0 26.5 18.8 40.5 34.5 7.5 48.6 17.4 39.6 19.8 21.4 21.8 16.0 38.7 16.8 16.9 21.9 49.1 13.0 55.9 14.3 17.7 22.6 28.8 48.9 31.5 25.9 13.1 17.7 39.9 35.7 18.0 24.0 30.6 18.5 20.0 23.0 17.0 18.8 43.3 27.8 66.7 15.1 45.3 22.6 40.5 9.3 16.6 7.4 9.3 8.7 21.8 9.3 9.1 12.2 20.3 8.8 6.9 16.3 7.1 14.7 15.8 12.8 5.9 24.6 24.9 31.2 38.4 25.3 25.6 24.6 24.6 24.5 24.8 25.4 26.2 24.6 25.6 39.7 43.1 75.4 122.6 29.6 21.5 55.8 24.2 43.8 23.0 16.0 40.0 33.6 20.2 20.9 13.8 40.5 60.7 37.2 25.5 34.8 44.6 17.8 27.1 46.6 52.0 72.1 25.7 12.4 23.6 35.2 55.9 46.9 17.8 17.5 36.8 20.8 37.0 62.9 40.3 20.3 45.2 77.9 55.1 15.8 52.1 23.2 65.6 60.8 35.0 26.8 52.3 67.0 27.3 43.0 20.7 60.5 42.6 29.0 70.5 40.2 32.9 26.3 25.3 21.2 43.1 21.9 59.0 123.5 27.2 36.5 10.2 40.3 46.1 AGPAT1 LPAAT-alpha ENSG00000204310 "1-acylglycerol-3-phosphate O-acyltransferase 1" Q99943 6 32168212-32178096 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late spermatids: 91.7" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebral cortex: 47.1" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048478, HPA073355" Approved Supported "Endoplasmic reticulum,Rods & Rings" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "Endoplasmic reticulum" "Rods & Rings" "HPA048478: AB_2680411, HPA073355: AB_2686596" "prognostic unfavorable (1.93e-4)" "unprognostic (9.35e-3)" "unprognostic (1.87e-3)" "prognostic unfavorable (5.21e-4)" "unprognostic (4.79e-2)" "unprognostic (7.05e-2)" "unprognostic (7.16e-3)" "unprognostic (1.55e-1)" "unprognostic (3.79e-1)" "unprognostic (4.24e-3)" "unprognostic (1.84e-3)" "unprognostic (1.77e-1)" "unprognostic (6.58e-2)" "unprognostic (1.97e-2)" "unprognostic (2.16e-1)" "unprognostic (9.92e-3)" "unprognostic (7.00e-2)" 46.6 60.3 3.0 5.9 7.2 6.6 42.6 2.5 47.1 58.2 2.9 61.3 28.2 64.3 42.9 33.9 56.5 18.9 66.9 4.0 25.5 61.6 60.2 44.2 10.9 3.8 9.5 67.2 37.5 9.3 53.8 15.9 4.4 53.2 20.1 12.5 34.1 0.0 67.7 35.1 53.0 1.5 2.5 39.8 58.4 79.3 3.3 18.4 54.1 33.5 12.5 58.2 42.7 4.7 0.0 0.4 51.2 0.3 127.5 85.2 49.4 0.0 0.0 0.0 0.0 104.5 0.0 0.0 46.1 128.0 36.4 13.4 108.5 39.4 0.0 0.4 83.6 0.0 0.0 111.7 0.0 0.0 101.5 51.0 47.6 0.0 46.0 105.9 31.6 86.7 78.5 66.0 109.2 28.8 0.4 26.8 0.0 0.1 18.0 0.6 0.0 0.5 32.8 0.0 0.0 0.1 51.3 16.1 70.4 51.6 63.4 0.0 25.9 0.0 20.3 0.0 0.2 45.9 41.1 18.0 64.3 0.1 0.3 3.4 5.6 12.4 7.6 8.2 7.4 5.3 5.0 8.6 9.3 5.0 4.3 6.4 9.4 8.7 5.8 11.6 7.2 6.9 3.0 7.2 2.5 47.1 4.0 25.5 3.8 9.5 4.4 2.5 3.3 4.7 32.1 16.0 18.6 11.1 14.3 9.1 14.0 20.6 16.5 26.1 26.2 21.6 4.0 14.3 12.0 36.8 12.5 35.2 24.5 28.7 5.9 17.9 63.9 14.1 24.9 21.3 29.4 12.0 13.8 14.3 29.9 19.6 16.3 11.4 12.7 22.7 27.1 31.2 24.7 32.0 17.7 24.3 18.3 22.3 20.6 91.7 13.4 24.9 8.8 11.2 13.0 38.5 21.6 10.1 14.8 17.0 22.3 21.4 16.9 10.2 73.6 29.4 12.9 17.9 0.0 18.3 22.9 44.8 22.1 9.5 3.7 15.3 13.8 21.5 20.8 12.1 ALCAM "CD166, MEMD" ENSG00000170017 "Activated leukocyte cell adhesion molecule" Q13740 3 105366909-105576900 "Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Adaptive immunity, Cell adhesion, Immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "parathyroid gland: 438.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 737.2;Oligodendrocyte precursor cells: 680.1;Oligodendrocytes: 981.1;Respiratory ciliated cells: 318.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 29.6" "Lineage enriched" "Detected in many" 6 "dendritic cells: 29.6" "Cell line enhanced" "Detected in many" "hTERT-HME1: 393.4;U-138 MG: 473.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002148, HPA010926" Enhanced Uncertain Vesicles "Secreted to blood" NA NA 1600000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "CAB002148: AB_442053, HPA010926: AB_1078449" "unprognostic (6.82e-2)" "unprognostic (2.66e-1)" "unprognostic (2.13e-1)" "unprognostic (2.19e-1)" "unprognostic (9.48e-3)" "unprognostic (2.08e-2)" "unprognostic (1.63e-3)" "unprognostic (3.89e-2)" "unprognostic (1.75e-1)" "unprognostic (4.01e-2)" "unprognostic (1.09e-1)" "unprognostic (1.07e-1)" "prognostic favorable (3.15e-4)" "unprognostic (3.15e-1)" "unprognostic (4.47e-2)" "unprognostic (9.57e-2)" "unprognostic (7.76e-2)" 7.7 32.7 31.3 12.2 48.1 10.5 81.0 42.4 47.2 28.0 14.4 16.6 17.0 15.5 35.4 8.2 49.1 23.3 9.6 32.4 70.6 22.2 47.9 74.1 9.9 50.7 54.9 57.6 32.7 438.9 19.2 12.1 51.7 32.7 14.5 3.6 33.8 39.6 0.8 11.0 17.4 16.2 44.9 6.3 33.4 4.5 45.7 14.2 62.4 5.0 14.5 25.6 6.4 85.0 248.4 93.7 65.9 33.7 97.6 42.7 0.6 197.7 115.1 124.9 173.8 0.8 50.5 17.3 80.3 280.6 68.8 186.5 10.6 157.4 366.1 16.6 16.6 2.4 65.8 4.6 109.6 101.3 0.8 76.0 114.9 159.9 393.4 346.8 139.3 17.9 0.3 28.6 165.9 16.9 14.5 37.0 13.7 79.3 104.8 9.4 5.9 1.0 188.9 27.2 47.5 131.9 20.6 19.6 12.9 25.9 37.7 66.3 291.6 473.7 162.3 20.9 237.2 0.3 0.6 1.8 108.0 21.1 207.4 0.0 4.7 3.5 0.6 2.1 1.9 4.7 1.5 0.9 29.6 3.0 0.3 0.2 5.3 0.6 1.2 10.5 2.4 3.2 31.3 48.1 42.4 47.2 32.4 70.6 50.7 54.9 51.7 44.9 45.7 85.0 4.5 737.2 143.6 238.6 17.9 12.1 22.8 65.8 12.0 3.0 112.4 47.9 10.1 62.9 255.3 16.5 2.1 0.7 19.5 9.1 1.9 18.5 66.5 108.6 20.1 11.9 16.8 6.3 143.0 43.0 0.7 37.0 23.4 158.1 11.4 29.5 3.6 44.1 57.5 1.7 287.0 16.3 46.8 51.0 162.6 60.1 3.7 86.4 24.9 40.3 93.4 1.3 1.0 680.1 981.1 55.2 8.5 6.4 21.8 117.5 9.6 24.2 318.3 0.8 0.0 7.9 21.8 8.1 5.5 30.1 20.2 0.8 8.9 22.8 10.4 105.4 ALDH1B1 "ALDH5, ALDHX" ENSG00000137124 "Aldehyde dehydrogenase 1 family member B1" P30837 9 38392702-38398661 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 172.7;smooth muscle: 128.0" "Cell type enhanced" "Detected in many" "Cholangiocytes: 85.8;Ductal cells: 64.1;Hepatocytes: 128.1;Proximal tubular cells: 165.0;Theca cells: 91.7;Undifferentiated cells: 71.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "OE19: 183.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021037, HPA077080" Enhanced Supported Nucleoplasm,Mitochondria,Cytosol NA NA 500000 "Cluster 27: Non-specific - Gene expression" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "Nucleoplasm, Cytosol" "HPA021037: AB_1844724, HPA077080: " "unprognostic (4.16e-1)" "unprognostic (1.98e-2)" "unprognostic (5.84e-2)" "unprognostic (1.55e-3)" "unprognostic (2.47e-2)" "unprognostic (4.48e-3)" "unprognostic (2.84e-3)" "unprognostic (2.70e-2)" "unprognostic (1.91e-1)" "unprognostic (1.35e-1)" "unprognostic (2.09e-1)" "unprognostic (1.00e-1)" "prognostic favorable (2.05e-4)" "unprognostic (1.04e-1)" "unprognostic (1.63e-1)" "prognostic unfavorable (1.17e-5)" "unprognostic (2.89e-2)" 21.2 10.4 3.2 31.4 3.2 2.9 8.9 4.1 4.0 8.5 6.4 61.5 22.9 57.7 5.7 32.7 34.9 29.0 14.7 2.7 4.8 59.2 172.7 7.3 5.1 3.5 3.3 12.6 11.3 8.5 2.5 5.2 4.3 36.9 35.5 1.5 11.1 54.5 55.8 6.3 24.8 128.0 3.4 7.2 28.2 8.3 4.0 5.1 15.4 35.9 5.6 85.1 10.5 4.1 72.2 65.5 19.8 31.8 27.6 32.5 15.8 33.6 16.9 27.8 28.3 44.2 13.7 45.2 19.7 47.4 42.0 10.0 66.0 71.4 27.4 50.8 28.5 22.4 44.7 132.2 20.0 36.0 24.0 39.0 15.3 22.6 19.5 56.6 26.8 10.6 65.6 42.8 42.8 27.3 0.1 14.4 59.1 183.3 29.0 14.9 119.9 34.5 25.1 31.7 43.3 19.9 25.7 16.7 19.4 20.6 15.9 27.9 18.2 31.9 52.4 26.9 42.5 6.5 13.2 17.8 16.4 36.0 22.1 0.3 4.2 0.2 6.7 9.2 9.6 5.5 6.5 6.1 9.5 2.6 5.1 6.2 1.0 8.0 11.9 1.2 5.0 5.3 3.2 3.2 4.1 4.0 2.7 4.8 3.5 3.3 4.3 3.4 4.0 4.1 3.3 9.6 1.7 0.0 3.7 1.0 5.7 9.4 2.2 1.2 3.7 4.2 6.6 85.8 3.8 16.5 2.1 2.0 1.2 12.8 17.6 64.1 0.6 2.3 6.4 4.7 15.6 12.8 0.5 6.9 46.6 6.6 8.2 3.4 8.9 12.8 8.9 128.1 7.2 0.0 1.1 25.5 6.1 4.1 2.4 2.2 6.5 4.2 0.0 0.0 5.5 2.1 0.0 0.5 0.5 15.0 7.7 6.8 3.7 6.1 10.3 165.0 0.3 0.7 0.0 6.0 16.1 0.6 0.8 2.1 1.0 1.8 3.3 91.7 71.7 2.8 ALDH3A2 "ALDH10, FALDH, SLS" ENSG00000072210 "Aldehyde dehydrogenase 3 family member A2" P51648 17 19648136-19685760 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease variant, Ichthyosis, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 288.6" "Cell type enhanced" "Detected in all" "Basal squamous epithelial cells: 287.4;Squamous epithelial cells: 232.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "OE19: 285.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014769, CAB020692" Enhanced Approved "Endoplasmic reticulum,Cytosol" NA NA 32000 "Cluster 14: Monocytes - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "Endoplasmic reticulum, Cytosol" "CAB020692: , HPA014769: AB_1844728" "unprognostic (1.42e-1)" "unprognostic (7.62e-2)" "unprognostic (7.77e-2)" "unprognostic (2.49e-2)" "unprognostic (4.59e-1)" "unprognostic (1.64e-1)" "unprognostic (1.59e-1)" "unprognostic (1.31e-2)" "unprognostic (2.23e-1)" "unprognostic (3.93e-3)" "unprognostic (2.40e-1)" "unprognostic (2.63e-1)" "prognostic favorable (3.85e-8)" "unprognostic (4.12e-2)" "unprognostic (1.55e-1)" "unprognostic (1.42e-2)" "unprognostic (1.26e-1)" 75.2 203.0 23.1 15.2 32.5 9.3 34.9 24.8 27.7 49.4 71.7 49.6 68.1 29.4 41.7 131.3 38.3 70.5 44.6 29.0 27.9 173.0 288.6 59.1 14.9 23.3 26.3 32.3 52.3 40.6 21.9 11.8 23.5 75.0 36.5 40.8 61.7 41.5 53.0 207.6 71.8 30.2 25.1 19.4 81.5 26.9 24.8 23.0 75.1 100.9 36.4 24.2 40.5 33.6 27.7 147.0 29.2 58.5 88.7 89.4 19.1 12.3 29.9 24.4 27.6 63.2 52.5 12.3 35.9 50.5 29.3 99.0 59.8 125.2 19.9 36.2 42.5 5.3 120.9 142.8 12.2 30.6 5.4 42.9 137.6 22.9 12.2 49.7 49.2 25.5 2.2 0.6 37.3 45.3 0.7 25.2 32.3 285.4 78.5 38.6 64.1 25.3 17.5 132.3 46.3 30.4 98.9 38.4 35.3 152.2 78.1 35.0 46.7 10.1 28.7 68.8 45.6 11.3 28.6 15.5 47.4 0.3 48.3 0.8 21.1 17.5 6.3 18.3 9.9 5.2 6.0 6.1 20.7 4.9 6.8 6.3 2.2 15.0 20.6 1.3 11.3 11.0 23.1 32.5 24.8 27.7 29.0 27.9 23.3 26.3 23.5 25.1 24.8 33.6 22.1 176.3 86.5 14.7 13.3 57.1 143.9 85.1 287.4 15.3 13.6 24.0 54.1 105.8 86.5 33.1 12.5 12.5 8.2 48.9 43.0 97.5 79.6 47.5 13.4 19.5 16.2 8.2 30.5 52.0 4.6 39.9 87.7 36.9 29.7 34.6 13.6 116.7 24.6 6.7 20.1 27.7 26.4 21.7 15.1 19.5 55.9 23.5 7.2 13.1 25.7 105.9 8.2 19.6 29.1 43.9 28.7 80.5 28.6 104.2 90.6 119.2 59.2 21.4 13.1 70.1 22.1 15.5 24.0 232.6 90.2 1.4 13.2 29.1 46.0 51.4 ALG1L ALG1L1 ENSG00000189366 "ALG1 chitobiosyldiphosphodolichol beta-mannosyltransferase like" Q6GMV1 3 125929275-125937039 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "epididymis: 10.8;urinary bladder: 9.4" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 33.6;Club cells: 15.2;Endometrial ciliated cells: 10.5;Ionocytes: 12.2;Respiratory ciliated cells: 46.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 15.9;CAPAN-2: 14.3;HaCaT: 15.2;MCF7: 30.1;OE19: 19.1;T-47d: 19.7" HPA036108 Uncertain NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA036108: AB_10673344" "unprognostic (7.06e-3)" "unprognostic (1.50e-3)" "unprognostic (1.47e-1)" "unprognostic (4.14e-2)" "prognostic favorable (3.00e-4)" "unprognostic (2.40e-2)" "unprognostic (1.86e-1)" "unprognostic (1.15e-1)" "unprognostic (2.10e-1)" "unprognostic (1.47e-1)" "unprognostic (4.37e-2)" "unprognostic (5.79e-2)" "unprognostic (4.50e-6)" "unprognostic (1.35e-1)" "unprognostic (3.30e-1)" "unprognostic (1.57e-2)" "prognostic favorable (6.24e-4)" 0.5 1.1 2.5 1.1 2.7 0.3 1.4 2.0 3.0 1.6 1.4 1.4 0.4 1.4 10.8 1.6 2.2 0.8 0.7 2.4 2.6 1.7 1.4 1.0 0.4 2.5 2.4 2.3 1.3 0.6 1.8 1.5 2.5 1.8 0.8 0.6 1.9 0.9 6.7 5.8 0.5 0.5 2.1 0.3 1.5 1.2 2.4 1.1 1.6 2.6 2.7 9.4 1.5 2.5 1.1 0.8 0.4 0.0 0.0 0.2 1.8 0.1 0.0 0.2 0.4 15.9 14.3 4.4 6.8 0.0 0.3 15.2 0.4 0.0 0.8 0.6 3.6 0.8 2.4 0.0 0.2 0.2 0.2 0.1 0.1 0.0 0.1 0.0 0.0 4.1 1.2 1.4 0.0 30.1 1.0 0.3 6.4 19.1 3.8 0.1 0.1 7.4 0.0 0.9 2.4 0.9 0.5 0.2 0.7 3.2 19.7 0.4 0.3 0.2 2.2 0.2 0.1 10.9 1.7 5.9 0.2 0.0 1.0 2.5 0.0 0.1 2.0 0.1 1.1 1.6 1.0 2.2 0.0 0.9 1.2 0.7 0.4 3.2 0.0 1.3 2.7 0.9 2.5 2.7 2.0 3.0 2.4 2.6 2.5 2.4 2.5 2.1 2.4 2.5 0.2 0.0 0.5 0.3 0.7 3.3 1.7 33.6 0.6 0.3 2.1 2.4 0.0 0.0 15.2 1.8 0.0 3.5 0.5 0.3 1.9 0.4 1.7 10.5 0.8 0.3 1.8 0.0 1.2 0.4 2.0 1.1 0.0 0.4 1.3 1.4 0.0 0.1 0.3 0.0 1.7 0.2 12.2 0.0 1.2 1.8 1.8 0.1 1.8 0.0 0.2 1.5 2.1 1.0 0.6 0.6 1.4 3.0 0.4 0.5 0.0 1.0 46.0 0.0 0.0 2.7 2.6 1.4 1.6 0.3 5.1 1.4 0.5 2.4 0.4 8.2 ALOXE3 "E-LOX, eLOX3" ENSG00000179148 "Arachidonate lipoxygenase 3" Q9BYJ1 17 8095900-8119047 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Dioxygenase, Isomerase, Lyase, Oxidoreductase" "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 27 "skin 1: 56.2" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 2.1;Pancreatic endocrine cells: 6.3;Prostatic glandular cells: 1.8;Spermatocytes: 1.8;Spermatogonia: 1.7;Suprabasal keratinocytes: 1.8" "Group enriched" "Detected in some" 4 "cervical cancer: 1.1;head and neck cancer: 3.9;melanoma: 1.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 6.4;HBEC3-KT: 10.1;hTCEpi: 7.3;hTERT-HME1: 13.7;T-47d: 4.4" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA023120, HPA078597" Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 30: Epithelial cell lines - Translation" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane, Cytosol" "HPA023120: AB_10959300, HPA078597: AB_2732385" "unprognostic (2.40e-1)" "unprognostic (3.01e-2)" "unprognostic (1.87e-3)" "unprognostic (2.09e-4)" "unprognostic (1.07e-2)" "unprognostic (4.06e-2)" "unprognostic (3.56e-4)" "unprognostic (3.60e-1)" "unprognostic (4.65e-2)" "unprognostic (3.82e-2)" "unprognostic (3.72e-1)" "unprognostic (3.66e-5)" "unprognostic (9.81e-2)" "unprognostic (2.55e-1)" "unprognostic (1.08e-2)" "unprognostic (2.88e-2)" 0.0 0.0 0.5 0.0 0.3 0.0 1.6 1.9 2.1 0.6 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.0 0.8 0.7 0.0 0.1 0.4 0.2 0.1 0.7 0.1 0.0 0.1 0.3 0.0 0.1 56.2 0.0 0.0 0.1 0.0 0.0 0.8 1.0 0.0 0.0 0.0 1.2 0.0 1.8 0.5 6.4 0.7 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.4 0.1 0.5 0.2 0.2 0.1 2.9 0.4 0.8 10.1 0.1 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 7.3 0.1 13.7 0.0 0.0 0.9 0.0 0.1 0.0 2.3 0.0 0.0 0.0 0.2 2.0 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.7 0.0 0.0 4.4 0.0 0.1 0.0 2.1 0.0 0.3 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 1.9 2.1 0.7 0.4 0.8 0.7 0.7 0.1 1.0 0.5 0.1 0.0 0.0 0.0 0.0 0.3 2.1 1.2 0.0 0.0 0.6 0.5 0.5 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.4 0.4 0.1 0.1 0.2 0.0 0.0 1.2 0.9 1.2 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.2 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.3 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.8 1.7 0.3 1.8 1.1 0.0 0.0 0.0 0.6 AMPD3 ENSG00000133805 "Adenosine monophosphate deaminase 3" Q01432 11 10308313-10507579 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 62.9;skeletal muscle: 73.3" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 111.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+: 44.2;CAPAN-2: 34.6;HMC-1: 36.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038662, HPA047408" Uncertain Approved "Nuclear membrane" NA NA 77000 "Cluster 49: Eosinophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nuclear membrane" "HPA038662: AB_2676136, HPA047408: AB_2680034" "unprognostic (2.24e-1)" "unprognostic (3.88e-3)" "unprognostic (1.44e-2)" "prognostic favorable (2.37e-4)" "unprognostic (1.89e-2)" "unprognostic (1.71e-3)" "unprognostic (2.91e-3)" "unprognostic (1.25e-1)" "unprognostic (7.83e-2)" "unprognostic (2.26e-1)" "unprognostic (1.84e-2)" "unprognostic (4.68e-1)" "unprognostic (3.06e-2)" "unprognostic (7.07e-2)" "unprognostic (4.42e-2)" "unprognostic (2.98e-1)" "unprognostic (2.12e-2)" 4.2 19.6 10.8 20.7 22.5 62.9 3.0 19.1 15.3 6.0 10.8 4.9 6.5 4.2 4.0 7.6 11.1 6.4 2.9 10.4 15.9 7.8 1.8 6.9 17.6 21.1 20.5 2.6 3.3 24.1 18.2 4.1 20.5 7.4 6.6 7.5 6.4 3.5 73.3 15.6 7.8 4.4 14.0 12.1 6.7 1.8 21.4 13.9 3.6 9.3 20.3 9.7 7.9 30.2 14.1 2.0 0.5 0.2 7.1 5.0 0.8 12.4 44.2 3.0 3.1 6.9 34.6 5.1 1.2 5.7 11.9 8.6 0.2 11.8 8.8 12.7 0.5 12.5 1.8 1.0 2.4 17.2 36.0 18.5 17.9 6.0 7.7 7.5 1.4 8.3 19.4 5.3 10.1 0.5 10.2 22.3 1.6 1.1 12.2 3.7 15.9 18.2 0.6 11.5 5.1 2.6 2.7 0.4 0.8 1.0 0.4 5.8 3.4 13.7 0.2 9.6 0.5 4.8 2.9 5.5 15.7 16.9 0.3 9.5 6.4 19.4 2.2 3.9 5.4 7.7 3.3 2.6 4.2 5.3 3.6 2.5 8.4 3.8 1.7 2.7 2.1 2.8 10.8 22.5 19.1 15.3 10.4 15.9 21.1 20.5 20.5 14.0 21.4 30.2 0.5 0.0 3.9 5.2 14.3 12.5 10.6 8.1 4.0 23.6 1.6 1.8 6.3 5.7 9.8 14.7 2.1 0.9 1.6 1.9 17.6 2.9 7.3 14.0 1.7 1.6 10.2 20.2 11.9 1.6 1.5 8.1 3.1 2.9 12.0 0.9 1.1 0.7 14.5 0.0 7.0 3.9 20.3 15.2 7.6 20.6 0.9 18.3 3.6 28.1 14.0 6.5 1.0 5.0 111.8 6.3 3.0 0.0 1.7 26.5 4.9 0.8 24.2 1.3 0.0 12.3 1.9 0.4 0.6 2.2 12.5 1.2 6.6 0.3 2.2 16.8 ANGPT2 Ang2 ENSG00000091879 "Angiopoietin 2" O15123 8 6499632-6563409 "Cancer-related genes, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 81.7;Endothelial cells: 182.2;Smooth muscle cells: 79.8" "Cancer enhanced" "Detected in all" "renal cancer: 12.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.7" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 8 "HMC-1: 17.9;HSkMC: 39.9;HUVEC TERT2: 62.6;WM-115: 22.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB011437, CAB017626" Approved "Secreted to blood" NA NA 3780000 110000 "Cluster 10: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "CAB011437: , CAB017626: AB_1118956" "unprognostic (1.28e-1)" "prognostic unfavorable (7.99e-5)" "unprognostic (1.93e-2)" "unprognostic (1.23e-1)" "unprognostic (4.85e-1)" "unprognostic (4.86e-2)" "prognostic unfavorable (6.36e-5)" "unprognostic (1.66e-3)" "prognostic unfavorable (4.48e-4)" "unprognostic (2.94e-3)" "unprognostic (6.19e-3)" "unprognostic (1.38e-1)" "prognostic unfavorable (1.52e-7)" "prognostic unfavorable (3.87e-4)" "unprognostic (1.12e-1)" "unprognostic (1.46e-2)" "unprognostic (6.44e-2)" 15.7 0.5 5.6 3.8 5.0 0.4 9.9 6.3 9.0 6.2 2.6 2.9 1.2 4.3 1.1 2.2 4.2 4.9 7.3 4.9 6.3 5.4 2.7 4.6 6.8 12.3 5.8 2.5 0.8 2.3 0.8 11.3 12.3 3.3 1.8 1.6 2.5 2.7 4.0 3.1 2.5 6.8 7.7 0.5 1.8 0.9 7.6 6.4 8.2 2.0 2.8 10.6 3.2 7.5 0.1 0.2 0.3 0.1 0.4 0.3 0.3 0.0 0.0 0.0 0.0 0.3 0.2 0.2 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.1 0.1 4.7 0.4 0.1 0.9 0.0 17.9 39.9 0.0 0.0 0.0 0.1 62.6 0.1 0.1 0.4 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.5 0.8 0.0 0.0 0.1 0.3 0.1 0.1 1.3 0.2 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.1 22.7 1.7 0.2 0.2 0.2 0.1 0.2 0.2 0.2 0.2 0.0 0.4 0.2 0.3 0.2 0.2 0.1 0.3 0.1 0.1 5.6 5.0 6.3 9.0 4.9 6.3 12.3 5.8 12.3 7.7 7.6 7.5 81.7 9.6 0.0 5.2 7.8 8.2 2.7 2.5 1.8 9.3 1.5 1.4 2.8 2.8 1.6 0.0 29.2 1.8 3.6 0.6 0.0 1.3 3.2 4.2 5.4 182.2 13.8 1.3 17.0 0.5 1.5 6.3 1.5 5.9 4.5 2.0 30.4 0.9 0.6 38.7 16.1 1.7 0.0 2.5 10.9 5.0 43.5 2.7 16.0 26.2 2.4 2.9 7.2 24.6 11.3 1.3 1.2 3.8 0.9 9.9 2.6 1.0 1.4 12.5 0.0 8.1 79.8 1.6 1.6 0.3 8.0 30.6 5.5 2.9 1.3 4.7 ANKRD18B bA255A11.3 ENSG00000230453 "Ankyrin repeat domain 18B" A2A2Z9 9 33524394-33573009 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 34.5;choroid plexus: 10.6" "Cell type enhanced" "Detected in many" "Early spermatids: 34.4;Excitatory neurons: 13.8;Muller glia cells: 22.3;Spermatocytes: 41.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "NB-4: 27.5" "HPA046346, HPA046695, HPA049923, HPA051288" Uncertain Uncertain "Nucleoli,Nucleoli rim,Cytosol" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 24: NB-4 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoli, Nucleoli rim" Cytosol "HPA046346: AB_2679631, HPA046695: , HPA049923: AB_2680954, HPA051288: AB_2681421" "unprognostic (4.71e-2)" "unprognostic (1.85e-1)" "unprognostic (4.85e-3)" "unprognostic (1.00e-2)" "unprognostic (1.13e-1)" "unprognostic (1.17e-2)" "unprognostic (1.29e-4)" "unprognostic (1.45e-2)" "unprognostic (9.84e-2)" "unprognostic (8.65e-2)" "unprognostic (2.54e-4)" "unprognostic (1.01e-2)" "unprognostic (6.43e-5)" "unprognostic (4.89e-2)" "unprognostic (9.75e-4)" "unprognostic (8.25e-2)" "unprognostic (5.18e-2)" 0.4 0.2 16.8 0.0 17.5 0.1 0.1 34.5 30.1 0.2 10.6 0.0 0.0 0.1 0.1 1.9 0.2 0.4 0.0 18.2 13.6 0.0 0.0 0.1 0.1 22.3 15.7 0.0 0.0 0.0 0.4 0.2 21.4 1.2 0.0 1.9 0.1 0.0 0.7 2.2 0.0 0.0 12.7 0.3 0.0 3.9 14.5 0.0 0.2 0.1 0.1 0.7 0.9 17.0 10.0 8.8 0.6 0.1 0.2 1.5 0.9 2.1 2.1 2.7 2.9 2.1 0.2 0.2 0.4 0.3 2.9 2.2 5.9 2.1 3.6 0.1 5.2 10.2 13.1 1.5 0.0 3.5 0.6 0.8 3.6 3.7 9.3 0.7 5.0 0.0 5.5 0.5 3.0 1.7 0.0 27.5 9.1 0.2 4.8 0.0 13.0 2.0 1.6 2.4 0.3 8.5 4.2 0.3 0.4 5.5 7.5 13.4 4.6 1.5 5.8 4.4 3.9 1.5 0.8 0.0 0.8 0.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.8 17.5 34.5 30.1 18.2 13.6 22.3 15.7 21.4 12.7 14.5 17.0 0.0 0.0 0.0 0.7 0.0 2.0 5.4 2.9 1.2 8.5 0.5 0.9 3.1 4.3 2.8 1.8 0.0 0.0 0.0 0.6 0.0 0.8 34.4 12.1 0.2 0.3 0.0 0.0 13.8 0.5 0.4 0.1 0.0 4.0 0.0 12.1 0.4 0.1 0.2 0.0 9.0 2.0 4.1 0.0 0.3 3.7 0.6 0.2 0.0 1.9 0.0 22.3 0.0 4.0 0.8 0.4 1.7 0.7 0.0 2.5 0.3 0.1 9.8 5.5 0.0 0.5 0.5 41.4 2.1 6.2 3.3 0.0 0.2 0.0 1.3 3.9 ANLN "ANILLIN, scra, Scraps" ENSG00000011426 "Anillin actin binding protein" Q9NQW6 7 36389821-36453791 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Actin-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 266.0" "Group enriched" "Detected in many" 5 "Early spermatids: 156.4;Oligodendrocytes: 441.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "HBF TERT88: 655.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005680, CAB033902, HPA050556, CAB062547, CAB068175" Enhanced Enhanced Nucleoplasm,Midbody Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 70: Brain - Nervous system development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm Midbody "CAB033902: AB_2058302, CAB062547: AB_2665622, CAB068175: AB_2665623, HPA005680: AB_2667388, HPA050556: AB_2681175" "unprognostic (4.23e-2)" "unprognostic (1.59e-3)" "unprognostic (1.49e-1)" "prognostic unfavorable (1.73e-4)" "unprognostic (1.67e-2)" "unprognostic (3.44e-2)" "prognostic unfavorable (5.97e-7)" "prognostic unfavorable (6.99e-5)" "unprognostic (2.69e-2)" "unprognostic (3.66e-2)" "prognostic unfavorable (2.00e-6)" "unprognostic (3.13e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (5.29e-2)" "unprognostic (1.34e-1)" "unprognostic (2.94e-2)" "unprognostic (4.04e-3)" 1.2 0.7 59.8 5.2 134.5 36.4 2.0 125.1 72.7 1.8 18.4 6.0 4.4 1.8 0.2 10.4 0.9 2.1 0.8 59.3 83.6 0.4 1.2 1.4 6.7 162.3 106.5 0.9 0.6 0.2 0.2 8.9 160.2 0.9 8.0 0.3 1.7 0.4 0.3 13.6 4.3 14.9 99.2 1.2 4.8 12.4 102.3 16.0 0.8 0.3 9.5 3.2 3.2 266.0 476.1 96.5 79.3 61.0 10.7 26.9 85.6 292.5 169.3 344.4 256.0 66.4 142.7 23.9 82.1 148.6 182.8 237.0 63.4 170.7 655.4 16.1 46.0 32.7 104.8 55.8 1.7 47.3 36.7 6.0 7.7 225.3 147.2 40.8 109.3 31.2 69.6 48.8 284.4 71.0 40.0 54.8 88.5 71.9 102.3 29.1 238.2 15.9 76.5 76.5 33.5 39.5 154.1 175.8 26.1 109.6 119.0 53.6 104.5 214.2 239.0 127.6 346.6 20.1 34.2 43.2 72.9 74.9 460.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.3 59.8 134.5 125.1 72.7 59.3 83.6 162.3 106.5 160.2 99.2 102.3 266.0 0.4 0.0 1.1 2.3 1.0 14.1 1.9 8.3 7.4 0.0 1.9 2.0 0.6 0.0 3.2 0.0 0.0 13.8 1.1 2.8 0.0 0.7 156.4 18.9 3.2 1.9 0.0 35.3 3.4 0.2 23.2 6.9 10.2 12.8 0.0 15.4 1.1 0.5 9.8 0.0 5.7 3.4 6.1 1.6 5.9 53.3 1.2 2.7 0.0 0.0 0.0 0.0 0.0 1.5 441.3 0.6 0.1 0.0 8.8 1.6 0.8 0.3 10.4 0.0 0.0 0.4 5.2 20.0 17.7 27.1 9.2 2.9 2.6 1.7 6.0 3.3 ANXA8 ANX8 ENSG00000265190 "Annexin A8" P13928 10 47460162-47484158 "Predicted intracellular proteins" "Blood coagulation, Hemostasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 217.6;skin 1: 266.2;vagina: 110.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 99.3;Astrocytes: 38.8;Club cells: 40.7;Excitatory neurons: 47.8;Fibroblasts: 34.5;Inhibitory neurons: 41.0;Microglial cells: 35.6;Oligodendrocyte precursor cells: 50.8;Oligodendrocytes: 48.1;Squamous epithelial cells: 63.6" "Group enriched" "Detected in many" 4 "cervical cancer: 14.3;head and neck cancer: 16.1;lung cancer: 4.3;urothelial cancer: 11.1" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "myeloid DC: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HaCaT: 394.3;HBEC3-KT: 622.3;hTCEpi: 357.6;hTERT-HME1: 134.2;RT4: 159.6" "HPA045246, HPA047451" Approved Nucleoplasm NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA045246: AB_2679271, HPA047451: AB_2680052" "unprognostic (8.32e-4)" "unprognostic (2.52e-1)" "unprognostic (2.44e-1)" "unprognostic (6.15e-2)" "unprognostic (1.82e-1)" "prognostic unfavorable (6.07e-4)" "unprognostic (5.94e-2)" "unprognostic (2.88e-2)" "unprognostic (2.40e-1)" "unprognostic (1.50e-2)" "prognostic unfavorable (2.68e-4)" "unprognostic (1.19e-1)" "unprognostic (7.55e-15)" "unprognostic (1.04e-2)" "unprognostic (9.94e-2)" "unprognostic (1.65e-1)" "unprognostic (1.39e-1)" 73.3 0.7 0.5 0.1 0.5 0.7 11.7 0.7 1.1 49.6 0.6 0.5 0.0 0.1 1.0 217.6 3.7 0.4 4.4 0.6 0.3 0.0 1.8 13.1 0.0 1.0 0.8 1.3 0.3 0.0 0.3 30.9 0.8 12.4 0.1 0.0 47.3 9.8 0.4 266.2 0.2 0.0 0.6 0.2 0.4 0.8 1.5 4.8 0.2 0.2 46.6 66.4 110.7 0.9 123.4 16.2 0.0 0.0 0.0 0.0 33.7 2.3 0.3 0.0 0.0 8.7 35.0 0.0 2.5 1.0 1.8 394.3 0.0 622.3 0.0 27.9 0.0 0.0 39.6 0.0 26.2 0.0 1.3 0.2 357.6 0.2 134.2 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 37.2 0.1 4.0 0.0 0.0 0.5 0.0 0.0 159.6 0.0 0.0 56.4 16.4 0.3 8.7 0.1 3.5 0.0 0.0 39.5 0.7 2.4 0.2 0.1 0.2 4.4 0.3 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.5 0.5 0.7 1.1 0.6 0.3 1.0 0.8 0.8 0.6 1.5 0.9 0.1 99.3 7.3 38.8 0.0 1.1 10.3 1.6 2.8 0.0 4.9 3.4 2.6 7.2 40.7 3.7 0.0 14.7 0.1 1.0 0.0 3.1 0.6 2.1 0.0 0.5 0.0 0.0 47.8 0.4 6.7 34.5 0.0 0.2 1.3 0.1 0.0 0.0 0.6 0.0 41.0 0.1 0.0 0.0 0.0 1.7 0.0 0.2 0.0 35.6 0.1 0.0 0.0 50.8 48.1 17.3 0.0 0.0 0.0 8.5 1.5 0.0 14.2 0.0 0.0 0.0 0.6 0.2 1.4 63.6 2.0 6.2 0.3 0.1 0.2 17.2 ANXA8L1 "ANXA8L2, bA145E20.2, bA301J7.3" ENSG00000264230 "Annexin A8 like 1" Q5VT79 10 46375627-46391784 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 195.2;skin 1: 325.4;vagina: 100.5" "Cell type enriched" "Detected in many" 4 "Squamous epithelial cells: 118.7" "Cancer enhanced" "Detected in many" "cervical cancer: 5.2;head and neck cancer: 5.6" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.2;myeloid DC: 2.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HaCaT: 374.5;HBEC3-KT: 485.0;hTCEpi: 140.1;SiHa: 116.6" "HPA045246, HPA047451" Approved Nucleoplasm NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA045246: AB_2679271, HPA047451: AB_2680052" "unprognostic (3.67e-3)" "unprognostic (4.56e-3)" "unprognostic (9.14e-3)" "unprognostic (3.92e-2)" "unprognostic (1.63e-1)" "unprognostic (1.64e-3)" "unprognostic (1.27e-2)" "unprognostic (1.08e-2)" "unprognostic (8.05e-2)" "unprognostic (6.94e-3)" "unprognostic (8.33e-5)" "unprognostic (3.43e-1)" "unprognostic (8.26e-10)" "unprognostic (1.39e-1)" "unprognostic (1.95e-1)" "unprognostic (1.52e-1)" "unprognostic (1.32e-1)" 39.8 0.2 0.0 0.0 0.0 1.2 21.9 0.0 0.1 45.2 0.0 0.3 0.0 0.1 0.0 195.2 6.1 0.1 2.9 0.0 0.0 0.0 1.1 16.5 0.0 0.0 0.0 0.9 0.3 0.0 0.2 24.1 0.0 6.8 0.0 0.0 40.8 4.5 1.1 325.4 0.1 0.0 0.0 0.1 0.3 0.8 0.0 4.3 0.1 0.0 35.1 37.4 100.5 0.0 70.1 18.2 0.0 0.0 0.0 0.0 24.8 0.9 0.1 0.0 0.0 1.9 12.6 0.0 0.6 0.3 0.5 374.5 0.0 485.0 0.0 28.9 0.0 0.0 33.3 0.0 9.3 0.0 0.7 0.0 140.1 0.2 58.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 70.2 0.2 0.7 0.0 0.0 0.8 0.0 0.0 76.0 0.1 0.0 116.6 12.0 0.0 7.2 0.0 0.7 0.0 0.1 12.2 0.1 0.3 0.0 0.1 0.0 2.8 0.1 0.2 0.0 1.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.9 1.1 0.0 0.0 0.0 3.0 0.2 11.4 1.6 2.3 2.4 3.7 18.6 19.9 0.0 0.0 14.8 0.0 3.0 0.0 0.7 0.4 1.0 0.0 0.9 0.0 0.0 0.0 0.2 11.4 12.8 5.6 0.1 0.0 0.0 0.4 0.0 0.7 0.0 0.0 0.5 0.0 0.0 0.0 1.6 0.3 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 9.7 1.4 0.0 1.2 2.5 5.2 0.0 10.9 0.2 13.1 0.0 1.5 0.3 2.4 118.7 1.1 6.3 0.6 0.0 0.2 5.9 AQP2 ENSG00000167580 "Aquaporin 2" P41181 12 49950737-49958878 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Diabetes insipidus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 92 "kidney: 386.9;seminal vesicle: 212.4" "Cell type enriched" "Detected in some" 440 "Collecting duct cells: 4143.6" "Group enriched" "Detected in some" 6 "renal cancer: 1.7;stomach cancer: 1.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 3.4;HEL: 1.1;HMC-1: 2.2;OE19: 3.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA046834 Enhanced NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA046834: AB_2679830" "unprognostic (2.10e-1)" "unprognostic (3.77e-2)" "unprognostic (6.96e-3)" "unprognostic (4.48e-3)" "unprognostic (3.60e-2)" "unprognostic (9.51e-2)" "unprognostic (2.21e-1)" "unprognostic (1.43e-2)" "unprognostic (2.65e-2)" "unprognostic (7.38e-3)" "unprognostic (5.92e-2)" "unprognostic (4.60e-2)" "unprognostic (2.01e-2)" "unprognostic (1.11e-1)" 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.7 0.0 0.0 0.2 1.5 0.0 0.0 386.9 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.4 212.4 0.0 0.2 0.0 0.0 0.0 0.0 0.9 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 3.8 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 4143.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.1 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 9.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.1 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 ARHGEF15 "ARGEF15, FLJ13791, KIAA0915, MGC44868, Vsm-RhoGEF" ENSG00000198844 "Rho guanine nucleotide exchange factor 15" O94989 17 8310241-8322514 "Predicted intracellular proteins" "GTPase activation, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 47.7;breast: 41.6" "Group enriched" "Detected in some" 4 "Adipocytes: 66.4;Endothelial cells: 48.9;Hepatic stellate cells: 37.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 48 "HUVEC TERT2: 40.4;TIME: 49.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA044443, HPA063495" Supported "Plasma membrane" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA044443: AB_10960424, HPA063495: AB_2685023" "unprognostic (3.02e-1)" "unprognostic (2.97e-1)" "unprognostic (1.18e-2)" "unprognostic (7.09e-3)" "unprognostic (3.82e-1)" "unprognostic (7.29e-4)" "unprognostic (1.43e-2)" "unprognostic (1.84e-1)" "unprognostic (1.42e-1)" "unprognostic (3.40e-1)" "unprognostic (1.06e-2)" "unprognostic (1.45e-1)" "unprognostic (2.23e-3)" "unprognostic (4.88e-2)" "unprognostic (1.33e-1)" "unprognostic (1.89e-1)" "unprognostic (9.56e-3)" 47.7 5.9 4.6 4.1 4.2 0.0 41.6 4.1 4.7 8.7 3.0 6.9 3.1 10.9 1.6 4.8 9.8 7.3 35.5 4.1 4.1 15.8 2.9 22.1 3.1 4.7 4.5 3.8 4.2 3.4 4.0 14.7 4.8 8.0 2.0 0.2 5.1 3.5 13.2 7.7 6.5 7.2 4.0 7.9 6.9 2.2 5.2 1.6 12.4 10.9 1.8 12.3 8.3 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 49.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 4.2 4.1 4.7 4.1 4.1 4.7 4.5 4.8 4.0 5.2 3.6 66.4 0.0 3.0 0.3 0.5 2.8 0.3 0.0 0.6 0.8 0.5 0.4 8.9 2.8 0.0 1.8 0.0 0.0 0.2 0.1 0.0 0.0 3.3 0.4 0.2 48.9 0.0 0.0 0.2 0.0 0.1 1.0 0.0 1.3 0.0 0.0 37.1 0.0 0.1 0.0 0.5 0.0 0.0 1.4 2.8 4.4 0.0 0.5 7.2 11.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.4 0.0 0.0 0.0 0.1 0.0 1.6 1.5 0.4 0.2 0.2 1.0 0.1 0.3 0.7 0.0 0.3 ARHGEF38 FLJ20184 ENSG00000236699 "Rho guanine nucleotide exchange factor 38" Q9NXL2 4 105552620-105708093 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 7.8;pancreas: 6.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 48.5;Breast glandular cells: 17.9;Respiratory ciliated cells: 31.9" "Cancer enhanced" "Detected in many" "prostate cancer: 5.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "OE19: 2.8;RPTEC TERT1: 14.3;SK-BR-3: 8.0;T-47d: 8.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA036510, HPA045484" Uncertain Approved Nucleoplasm,Centrosome NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 35: Glandular cells - Unknown function" Nucleoplasm Centrosome "HPA036510: AB_10672357, HPA045484: AB_2679345" "unprognostic (1.49e-1)" "unprognostic (1.01e-1)" "unprognostic (1.62e-1)" "unprognostic (6.19e-3)" "unprognostic (2.09e-2)" "unprognostic (2.24e-3)" "unprognostic (1.85e-1)" "unprognostic (5.47e-3)" "unprognostic (2.79e-1)" "unprognostic (6.14e-5)" "unprognostic (1.17e-1)" "unprognostic (3.53e-3)" "unprognostic (3.16e-8)" "unprognostic (2.33e-3)" "unprognostic (6.16e-2)" "unprognostic (3.19e-3)" "unprognostic (6.45e-3)" 0.0 0.0 0.0 0.3 0.0 0.0 7.8 0.0 0.0 2.5 0.0 2.6 1.9 0.2 5.5 0.1 0.6 3.2 0.0 0.0 0.0 3.9 0.1 3.6 0.0 0.0 0.0 0.0 6.5 0.0 2.0 0.0 0.0 5.7 4.2 0.0 4.9 0.4 0.3 0.5 2.6 0.0 0.0 0.0 3.1 0.0 0.0 0.0 1.4 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 2.8 0.3 0.0 0.0 0.1 14.3 0.0 0.0 0.0 0.0 8.0 0.0 0.0 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.4 48.5 0.0 0.2 0.0 1.1 1.1 0.0 0.0 17.9 6.1 1.8 4.3 12.6 12.9 0.0 0.2 0.2 9.8 9.8 6.8 1.9 12.6 0.5 0.3 8.4 0.0 0.3 5.8 0.1 0.3 9.2 7.8 0.0 0.0 0.0 0.1 0.1 0.0 0.3 14.8 10.2 0.0 0.2 0.4 0.0 0.1 3.6 0.0 0.0 0.0 0.0 0.0 0.1 2.4 6.4 0.0 0.1 9.4 4.8 0.5 31.9 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.4 0.0 11.4 0.8 ARMC7 FLJ22160 ENSG00000125449 "Armadillo repeat containing 7" Q9H6L4 17 75109952-75130272 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 39.5" "Cell type enhanced" "Detected in many" "Distal tubular cells: 35.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024229, HPA053076" Uncertain Supported Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA024229: AB_2059152, HPA053076: AB_2682036" "unprognostic (1.35e-1)" "prognostic favorable (2.98e-4)" "unprognostic (7.73e-2)" "unprognostic (5.84e-2)" "unprognostic (4.15e-2)" "unprognostic (5.32e-2)" "prognostic unfavorable (2.24e-5)" "unprognostic (2.84e-2)" "unprognostic (3.68e-1)" "unprognostic (4.28e-2)" "unprognostic (3.40e-2)" "unprognostic (4.86e-2)" "prognostic favorable (1.27e-4)" "unprognostic (1.93e-2)" "unprognostic (1.37e-1)" "unprognostic (1.16e-1)" "unprognostic (2.98e-2)" 7.4 6.7 7.3 5.8 7.5 4.1 7.4 12.7 9.0 7.7 7.7 12.4 9.6 7.0 4.8 11.2 6.6 4.7 8.8 7.6 7.7 39.5 13.2 12.3 7.0 7.3 7.1 5.2 7.0 6.6 7.0 5.8 7.6 11.8 6.9 2.7 8.9 6.4 5.5 12.0 11.9 4.0 7.0 14.0 11.4 7.3 7.9 8.2 9.9 3.9 6.4 8.7 9.3 7.9 15.2 30.2 8.9 8.5 7.0 4.3 9.4 8.3 9.0 15.9 14.3 25.3 14.7 9.0 10.8 7.7 8.7 12.4 14.6 6.1 7.6 8.7 23.2 17.5 13.4 15.9 15.5 13.5 16.1 5.6 11.4 10.0 5.8 7.7 14.6 14.5 15.8 17.6 5.3 21.7 25.9 14.8 4.5 32.8 22.6 14.6 18.0 16.8 35.6 27.4 8.3 11.9 15.6 15.7 18.6 15.2 18.4 12.9 11.3 16.1 14.9 6.4 13.1 14.7 5.5 12.7 7.2 9.6 11.8 31.7 13.7 28.5 18.0 9.9 15.8 13.4 12.9 15.1 12.7 10.0 9.8 14.9 18.6 15.7 7.9 11.1 20.8 11.7 7.3 7.5 12.7 9.0 7.6 7.7 7.3 7.1 7.6 7.0 7.9 7.9 6.6 12.8 8.8 1.3 10.4 4.6 2.8 5.8 2.2 6.0 6.0 5.1 2.5 7.2 5.2 22.0 0.0 14.1 10.1 28.6 35.2 8.7 6.2 4.6 3.0 9.0 6.0 1.7 3.0 9.4 8.3 4.1 8.6 5.1 10.8 4.4 14.3 4.6 15.2 0.0 2.9 9.8 6.1 7.5 3.3 12.2 5.3 9.7 12.4 1.9 13.9 3.3 11.3 2.5 1.8 11.3 27.1 3.8 6.4 4.8 15.8 15.4 7.2 3.4 19.7 2.2 4.6 3.8 5.9 4.4 4.5 4.9 8.7 6.6 12.4 3.8 ASCL2 "ASH2, bHLHa45, HASH2" ENSG00000183734 "Achaete-scute family bHLH transcription factor 2" Q99929 11 2268498-2270588 "Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 6.9;salivary gland: 8.0;skin 1: 7.3" "Cell type enriched" "Detected in many" 9 "Extravillous trophoblasts: 1042.9" "Group enriched" "Detected in many" 5 "colorectal cancer: 76.1;stomach cancer: 23.1" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 7.9" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 5 "BEWO: 25.1;NB-4: 8.1;OE19: 14.2;SCLC-21H: 20.5" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "unprognostic (2.71e-3)" "prognostic favorable (5.11e-4)" "unprognostic (2.03e-1)" "unprognostic (2.33e-2)" "unprognostic (1.72e-1)" "unprognostic (2.69e-2)" "unprognostic (2.93e-2)" "unprognostic (7.88e-2)" "unprognostic (3.79e-2)" "unprognostic (1.22e-2)" "prognostic favorable (4.73e-4)" "unprognostic (5.85e-2)" "unprognostic (1.45e-6)" "unprognostic (8.86e-3)" "unprognostic (5.48e-2)" "unprognostic (6.12e-4)" "unprognostic (1.07e-3)" 0.3 0.2 1.0 1.2 0.6 0.8 0.7 0.5 0.9 2.4 0.4 3.9 6.9 2.2 0.5 1.6 0.4 0.1 0.1 0.9 0.5 1.7 0.8 0.6 0.7 1.7 2.0 0.1 0.7 0.1 0.1 5.5 1.0 2.3 2.5 0.0 8.0 1.6 0.2 7.3 5.5 0.1 1.1 2.3 2.1 0.8 1.4 0.5 0.5 0.0 0.6 1.5 1.9 2.3 0.0 0.0 0.4 0.0 0.0 0.0 25.1 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.9 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 2.7 0.0 8.1 0.6 14.2 0.0 0.0 0.0 0.0 0.0 0.6 20.5 0.1 0.0 0.5 0.0 0.0 2.5 1.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 3.9 1.2 7.9 2.2 1.7 0.1 0.0 0.5 1.3 0.8 0.0 0.1 1.3 0.9 0.0 1.4 0.0 0.0 0.4 1.0 0.6 0.5 0.9 0.9 0.5 1.7 2.0 1.0 1.1 1.4 2.3 1.2 0.0 0.0 0.0 1.4 13.6 14.1 3.3 23.3 0.0 7.2 3.3 0.9 1.5 0.7 20.2 0.0 18.7 29.2 14.4 7.9 0.2 0.1 1.4 4.7 2.6 78.2 4.4 0.0 0.0 1042.9 1.5 10.2 3.5 0.0 0.0 23.2 0.5 31.1 0.0 0.0 31.4 2.0 22.0 7.0 0.2 1.8 14.3 1.8 3.7 22.6 0.0 110.2 0.0 0.0 0.0 3.6 1.5 1.3 6.5 9.1 0.4 1.0 0.1 0.0 0.1 0.3 0.3 13.7 9.1 4.7 23.3 8.9 0.1 112.1 9.4 ASF1B FLJ10604 ENSG00000105011 "Anti-silencing function 1B histone chaperone" Q9NVP2 19 14119512-14136613 "Predicted intracellular proteins" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Chaperone, Chromatin regulator, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 23.2;testis: 32.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 36.1;Early spermatids: 36.4;Erythroid cells: 43.6;Extravillous trophoblasts: 35.4;Spermatocytes: 73.2;Spermatogonia: 87.8" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 7 "neutrophil: 60.1" "Lineage enriched" "Detected in all" 7 "granulocytes: 60.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA054036, HPA069385" Enhanced Supported Nucleoplasm NA Yes "Cluster 9: Neutrophils - Innate immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA054036: AB_2682350, HPA069385: " "unprognostic (3.14e-1)" "prognostic favorable (4.45e-5)" "unprognostic (2.41e-3)" "unprognostic (2.40e-1)" "unprognostic (2.15e-1)" "unprognostic (2.27e-2)" "prognostic unfavorable (2.03e-4)" "unprognostic (2.87e-2)" "unprognostic (1.33e-3)" "unprognostic (1.52e-1)" "prognostic unfavorable (1.98e-4)" "unprognostic (8.48e-3)" "prognostic unfavorable (2.22e-16)" "prognostic favorable (2.49e-4)" "unprognostic (1.27e-1)" "unprognostic (3.92e-2)" "unprognostic (4.31e-2)" 0.9 1.4 0.2 5.6 0.3 11.7 1.3 0.3 0.2 2.2 0.1 7.4 5.3 1.0 0.1 10.3 0.7 0.7 0.7 0.1 0.2 1.0 1.3 2.1 12.5 0.3 0.2 0.7 0.7 0.3 0.7 3.6 0.3 0.8 7.7 0.0 1.9 0.3 0.5 3.2 6.0 2.0 0.2 6.7 3.2 32.0 0.3 23.2 0.6 0.4 14.7 1.8 3.2 0.3 64.6 25.3 37.7 28.9 3.8 3.6 16.2 33.1 28.3 63.8 79.5 26.5 31.6 59.1 30.0 17.5 26.5 38.0 41.8 24.1 49.7 54.0 26.9 55.5 48.7 18.6 0.2 39.0 35.1 0.7 1.7 35.8 12.4 7.2 25.1 44.1 50.2 83.8 31.8 75.7 80.8 34.3 17.3 69.1 56.7 77.0 56.0 51.6 20.1 28.3 46.0 16.5 39.8 29.2 17.4 10.3 22.1 41.5 10.6 36.0 21.6 91.0 56.6 43.2 46.5 80.3 28.0 71.9 36.1 0.7 6.2 1.5 1.7 8.0 0.9 1.1 1.5 2.0 1.2 0.9 0.9 1.7 60.1 1.7 8.5 0.5 5.1 3.2 0.2 0.3 0.3 0.2 0.1 0.2 0.3 0.2 0.3 0.2 0.3 0.3 1.0 0.0 0.6 0.3 5.6 2.5 2.4 4.5 1.2 0.1 4.8 8.5 1.2 1.5 1.1 0.0 0.0 36.1 3.8 11.7 0.0 1.0 36.4 2.1 1.3 2.1 1.2 43.6 0.5 1.2 35.4 4.1 23.4 2.3 4.5 9.2 0.4 0.3 21.5 0.0 0.4 9.9 8.2 5.6 5.6 29.1 0.0 5.0 1.8 1.0 2.1 0.3 4.1 0.0 0.5 1.1 2.2 0.7 20.1 1.0 2.4 0.3 0.2 0.9 0.0 1.1 3.3 73.2 87.8 8.3 1.1 10.4 5.3 3.0 20.9 2.4 ATAD2 "ANCCA, CT137, DKFZp667N1320, MGC29843, MGC5254, PRO2000" ENSG00000156802 "ATPase family AAA domain containing 2" Q6PL18 8 123319850-123416350 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 28.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 79.1;Spermatocytes: 106.0;Spermatogonia: 82.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 294.4" "Low region specificity" "Detected in all" "HPA029424, CAB056158" Enhanced Enhanced Nucleoplasm Yes Yes "Cluster 33: Neutrophils - Chromatin organization" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB056158: AB_2665580, HPA029424: AB_10611680" "unprognostic (1.56e-1)" "unprognostic (4.55e-2)" "unprognostic (2.07e-1)" "prognostic unfavorable (2.04e-4)" "unprognostic (2.08e-1)" "unprognostic (4.44e-2)" "unprognostic (2.98e-2)" "unprognostic (2.74e-3)" "unprognostic (2.02e-3)" "unprognostic (5.62e-2)" "unprognostic (1.19e-2)" "unprognostic (4.98e-2)" "prognostic unfavorable (8.33e-15)" "unprognostic (1.15e-2)" "unprognostic (1.82e-1)" "unprognostic (4.84e-2)" "unprognostic (6.17e-2)" 2.9 3.4 3.8 7.7 3.6 26.5 6.8 2.6 3.9 12.8 2.0 5.3 5.0 4.3 3.8 6.8 3.4 3.2 5.8 3.2 4.5 1.4 9.9 4.1 14.4 2.9 3.8 7.0 3.3 1.9 3.9 4.8 2.6 10.3 6.9 1.4 4.3 4.7 9.3 6.8 5.2 4.1 2.8 4.9 4.7 18.9 5.1 28.3 3.9 3.2 12.8 4.8 3.9 2.8 103.7 39.6 55.0 19.0 9.7 12.3 24.3 79.2 27.2 66.8 73.9 30.1 43.8 67.2 23.6 25.2 26.5 48.3 74.2 25.6 106.1 94.3 39.0 121.2 41.0 61.4 3.8 44.6 57.4 4.1 3.8 63.6 21.0 14.3 20.7 38.6 57.7 66.4 50.4 107.1 129.5 32.8 10.0 77.8 38.4 66.5 65.6 36.4 23.8 46.7 70.2 30.5 114.4 294.4 20.8 22.1 60.2 41.2 13.0 50.4 69.3 40.2 96.6 21.2 40.7 60.8 32.9 72.9 40.4 5.3 0.8 3.3 1.6 0.8 2.2 2.6 2.3 2.7 1.4 1.5 1.5 1.7 0.2 2.5 1.9 0.1 4.6 1.0 3.8 3.6 2.6 3.9 3.2 4.5 2.9 3.8 2.6 2.8 5.1 2.8 4.8 6.4 11.0 9.4 18.5 15.8 27.9 9.1 14.2 2.8 17.3 21.2 27.3 2.8 10.2 3.7 4.2 14.9 15.3 9.0 1.9 3.5 54.9 7.9 17.3 9.6 1.2 79.1 25.6 2.2 26.2 17.1 13.3 17.5 14.5 37.9 7.1 16.3 11.2 1.7 16.4 13.1 4.1 8.2 6.9 24.4 7.5 11.7 1.8 14.0 6.3 6.3 17.5 11.6 2.8 3.5 4.3 13.9 34.0 20.7 3.1 1.0 5.4 1.9 0.0 9.5 17.5 106.0 82.4 23.7 12.1 13.5 22.8 3.7 14.6 24.5 ATP2B4 "ATP2B2, MXRA1, PMCA4" ENSG00000058668 "ATPase plasma membrane Ca2+ transporting 4" P23634 1 203626787-203744081 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calmodulin-binding, Translocase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 175.3" "Cell type enhanced" "Detected in many" "Adipocytes: 171.6;Oligodendrocyte precursor cells: 199.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "BJ: 200.0;BJ hTERT+: 276.4;fHDF/TERT166: 212.8;SuSa: 222.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016118, HPA040431" Enhanced Supported "Plasma membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "CAB016118: AB_2061729, HPA040431: AB_2676980" "unprognostic (7.43e-2)" "unprognostic (1.58e-1)" "unprognostic (1.60e-2)" "unprognostic (8.17e-2)" "unprognostic (2.53e-2)" "unprognostic (9.23e-3)" "unprognostic (8.68e-2)" "unprognostic (3.81e-2)" "unprognostic (9.74e-2)" "unprognostic (1.70e-1)" "unprognostic (1.64e-2)" "unprognostic (1.12e-1)" "prognostic unfavorable (1.21e-4)" "unprognostic (3.52e-3)" "unprognostic (2.61e-2)" "unprognostic (1.30e-1)" "unprognostic (2.56e-3)" 58.9 25.0 39.7 25.6 36.3 16.0 16.6 0.0 33.5 47.5 0.3 58.2 12.5 104.5 20.1 32.5 48.4 25.2 59.5 40.2 13.3 9.9 9.3 35.1 12.8 8.0 8.0 40.6 9.9 11.8 3.8 40.6 11.2 33.0 30.2 42.5 7.1 69.7 14.4 54.8 14.4 175.3 0.2 12.2 15.4 27.4 44.7 21.7 15.1 27.7 19.4 37.2 15.3 2.6 45.7 7.8 15.6 15.1 120.4 175.1 84.5 200.0 276.4 32.1 27.4 3.8 22.8 9.8 28.8 212.8 43.5 43.5 22.6 27.7 34.3 126.5 8.0 28.7 37.4 2.5 43.1 42.0 51.3 130.5 26.9 102.9 16.2 81.6 63.5 57.1 12.9 20.3 25.1 2.5 44.3 14.5 9.7 8.7 24.2 22.3 11.6 16.7 11.3 4.0 4.6 6.7 68.3 10.5 30.2 222.1 9.3 21.4 54.9 80.5 11.4 136.6 48.3 13.4 20.9 5.4 80.7 31.0 24.5 3.2 2.0 0.0 8.7 1.3 6.4 0.9 5.4 7.2 2.2 0.3 1.3 3.4 4.0 3.8 2.2 3.7 5.7 2.7 39.7 36.3 0.0 33.5 40.2 13.3 8.0 8.0 11.2 0.2 44.7 2.6 171.6 89.8 68.2 127.6 9.9 97.1 18.9 43.1 41.5 4.8 11.2 9.4 76.5 7.2 35.0 18.4 2.1 27.9 56.2 2.2 0.0 35.3 5.8 78.0 92.4 67.6 23.9 35.9 55.9 14.9 18.9 56.0 13.7 89.7 10.1 30.6 58.9 18.2 38.5 117.8 9.8 2.4 14.2 14.7 38.8 4.8 43.8 20.4 26.6 37.5 18.1 136.1 66.9 199.0 40.4 31.4 11.1 38.0 27.6 48.2 7.2 3.3 39.7 7.8 19.7 50.7 81.2 21.7 2.8 54.7 150.9 26.0 59.7 8.0 3.3 62.0 ATP6V1F "ATP6S14, VATF, Vma7" ENSG00000128524 "ATPase H+ transporting V1 subunit F" Q16864 7 128862856-128865847 "Metabolic proteins, Predicted intracellular proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 1054.6;Hofbauer cells: 1132.8;Proximal tubular cells: 1076.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009529, HPA048700, HPA062011" Supported NA NA 26000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 4: Macrophages - Innate immune response" "CAB009529: AB_2290237, HPA048700: AB_2680498, HPA062011: AB_2684656" "unprognostic (1.70e-1)" "unprognostic (1.61e-2)" "unprognostic (2.14e-2)" "unprognostic (3.26e-2)" "unprognostic (2.99e-2)" "unprognostic (8.46e-3)" "prognostic unfavorable (3.62e-4)" "unprognostic (6.28e-3)" "unprognostic (2.70e-1)" "unprognostic (1.04e-2)" "unprognostic (1.41e-1)" "unprognostic (4.06e-1)" "prognostic favorable (2.49e-5)" "unprognostic (2.20e-1)" "unprognostic (2.43e-1)" "unprognostic (1.36e-2)" "unprognostic (7.33e-2)" 133.3 160.7 275.6 106.2 290.1 210.4 122.3 272.7 368.6 126.5 250.2 104.6 74.7 95.3 61.7 223.0 98.3 104.2 183.3 294.8 300.1 307.0 84.2 140.0 139.9 280.1 275.3 89.0 106.8 163.5 141.0 104.6 286.0 103.0 56.6 110.6 129.3 81.6 169.3 170.1 97.0 71.2 269.5 119.6 114.4 212.2 284.3 119.6 84.6 154.7 103.7 123.1 146.6 277.4 305.6 345.1 151.2 323.2 297.6 236.8 86.9 151.2 201.3 246.8 267.2 257.0 179.8 287.6 156.5 175.7 367.7 163.9 224.5 250.1 91.9 312.6 364.2 220.1 211.4 256.4 344.1 227.1 400.8 278.2 340.0 284.7 163.4 188.9 238.1 257.9 534.3 297.3 276.3 403.1 381.0 494.3 201.9 190.6 281.4 168.7 110.1 467.5 315.5 240.3 286.6 197.3 214.1 796.5 363.7 156.6 184.4 284.9 253.0 303.5 65.3 409.5 236.2 333.5 326.9 372.0 600.4 315.5 263.6 370.2 697.1 489.2 244.6 475.1 238.0 343.7 247.6 239.7 508.9 348.5 235.8 238.6 203.1 243.6 324.7 288.3 317.3 886.1 275.6 290.1 272.7 368.6 294.8 300.1 280.1 275.3 286.0 269.5 284.3 277.4 129.3 28.9 62.8 17.3 140.1 237.6 202.5 378.9 136.6 111.4 162.0 190.1 157.6 127.2 230.7 331.1 37.5 171.8 119.8 97.3 1054.6 241.0 574.0 128.6 96.3 163.1 113.2 63.1 27.0 222.2 289.0 155.1 78.5 131.0 275.1 114.0 124.6 112.0 1132.8 545.1 34.6 108.7 585.9 320.6 378.7 898.9 164.4 456.1 254.3 16.9 285.8 230.4 190.5 11.6 26.2 253.9 93.0 127.9 136.8 224.7 212.0 1076.3 200.2 96.4 85.5 69.7 168.9 399.6 102.0 328.4 326.6 401.4 136.3 184.5 98.9 362.7 ATPAF2 "ATP12, Atp12p, LP3663, MGC29736" ENSG00000171953 "ATP synthase mitochondrial F1 complex assembly factor 2" Q8N5M1 17 17977409-18039209 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Chaperone "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SuSa: 104.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023329, HPA059422" Supported Enhanced Cytosol No No "Cluster 28: Myeloid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 12: NES - Nervous system development" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "HPA023329: AB_1845209, HPA059422: AB_2684011" "unprognostic (3.16e-2)" "unprognostic (1.98e-2)" "unprognostic (4.40e-2)" "prognostic favorable (4.95e-4)" "unprognostic (1.82e-1)" "unprognostic (1.27e-1)" "unprognostic (1.22e-1)" "unprognostic (1.31e-1)" "unprognostic (1.07e-1)" "unprognostic (1.55e-1)" "unprognostic (2.70e-3)" "unprognostic (1.67e-2)" "prognostic favorable (6.00e-5)" "unprognostic (1.32e-1)" "unprognostic (2.53e-1)" "unprognostic (5.15e-1)" "unprognostic (2.62e-2)" 8.6 18.5 7.4 8.6 7.6 15.9 8.7 8.3 11.1 8.4 8.3 11.1 8.7 6.8 8.7 14.4 8.1 4.9 23.9 7.5 9.1 16.1 19.7 7.8 10.5 7.9 8.1 7.3 9.8 26.3 9.3 7.7 8.4 9.1 10.4 6.4 10.7 6.6 24.7 14.6 10.2 8.4 7.8 10.4 12.0 10.9 7.8 10.8 10.6 27.8 14.5 9.1 9.5 8.4 13.0 24.1 15.4 14.7 15.1 16.2 15.6 11.2 16.4 23.7 20.1 31.8 19.3 26.0 24.6 19.5 13.1 19.9 14.8 24.1 20.7 20.9 11.7 5.8 14.8 18.6 25.5 8.2 17.3 19.5 16.8 21.4 11.9 16.7 27.4 21.3 9.3 8.9 13.1 26.8 19.4 12.8 10.4 48.3 13.3 19.8 27.1 29.9 19.0 11.4 9.9 13.5 14.9 7.6 14.0 104.2 24.4 16.2 11.6 6.0 12.4 22.2 10.9 6.2 8.4 9.6 10.7 11.9 31.4 7.8 41.5 14.7 9.3 28.6 10.4 27.9 6.9 8.9 49.2 19.7 10.7 8.0 3.0 8.9 22.3 41.6 12.9 20.7 7.4 7.6 8.3 11.1 7.5 9.1 7.9 8.1 8.4 7.8 7.8 8.4 8.8 6.4 7.8 9.4 20.3 15.3 12.0 23.7 9.6 10.5 13.9 10.8 28.2 20.0 14.4 12.9 33.3 32.5 20.7 10.9 66.5 19.3 52.9 10.5 6.0 10.0 14.5 13.7 13.7 12.3 30.9 9.1 8.2 8.5 13.3 25.7 9.3 20.8 45.5 10.1 14.1 18.2 16.2 22.3 22.5 42.6 6.5 18.2 17.8 7.5 28.1 13.8 13.4 9.0 9.6 16.0 24.4 6.8 18.6 13.8 25.8 58.8 17.2 17.7 0.0 8.4 10.4 28.2 20.9 17.6 18.9 28.7 9.0 15.9 20.5 12.3 B3GALT5 "B3GalT-V, B3T5, beta3Gal-T5, GLCT5" ENSG00000183778 "Beta-1,3-galactosyltransferase 5" Q9Y2C3 21 39556442-39673137 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "intestine: 37.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 196.4;Intestinal goblet cells: 47.4;Paneth cells: 72.5;Proximal enterocytes: 94.1;Undifferentiated cells: 57.7" "Cancer enhanced" "Detected in many" "pancreatic cancer: 5.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "CAPAN-2: 23.5;RPTEC TERT1: 27.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 8.6" "HPA054092, HPA054684" Approved "Intracellular and membrane" NA NA "Cluster 9: Intestine - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA054092: AB_2682375, HPA054684: AB_2682573" "unprognostic (1.40e-2)" "unprognostic (2.05e-1)" "unprognostic (1.52e-1)" "prognostic favorable (6.36e-4)" "unprognostic (9.23e-2)" "unprognostic (4.62e-2)" "unprognostic (4.06e-2)" "unprognostic (2.04e-1)" "unprognostic (2.48e-1)" "unprognostic (3.25e-2)" "unprognostic (7.86e-3)" "unprognostic (1.67e-1)" "unprognostic (6.09e-4)" "unprognostic (1.12e-1)" "unprognostic (2.46e-1)" "unprognostic (2.01e-2)" "unprognostic (2.55e-3)" 0.0 0.3 2.5 0.9 8.6 0.0 2.6 0.7 3.7 2.2 1.9 22.4 27.3 0.7 1.3 1.6 1.3 5.5 0.0 2.4 4.6 0.2 0.1 0.1 0.0 2.0 2.1 0.3 3.3 0.0 1.8 0.0 1.3 0.4 37.4 0.8 4.5 0.1 0.0 0.8 33.7 0.8 1.3 0.0 5.0 0.4 6.9 1.0 1.2 0.3 2.0 1.3 2.3 0.7 0.0 0.9 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 23.5 0.0 0.2 0.2 2.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 6.3 0.2 0.6 0.0 2.7 0.1 27.1 1.7 4.6 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.8 0.7 0.2 1.0 0.0 0.0 0.0 1.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 8.6 0.7 3.7 2.4 4.6 2.0 2.1 1.3 1.3 6.9 0.7 0.1 0.0 0.0 6.5 0.3 0.0 0.5 0.1 0.0 7.4 8.0 8.1 2.2 10.0 5.3 5.5 0.0 0.0 0.2 196.4 0.0 7.5 0.4 0.2 5.9 0.4 28.9 0.0 3.6 4.7 0.0 0.2 13.3 0.2 4.5 0.8 0.0 0.0 0.0 0.0 4.8 47.4 0.0 0.0 0.0 1.1 0.6 0.0 0.0 0.0 0.0 1.4 0.0 11.1 1.0 9.2 72.5 0.0 0.0 0.6 94.1 0.1 1.5 0.2 0.0 0.1 0.4 0.1 1.7 0.5 0.0 0.0 0.5 0.0 57.7 9.7 B4GALNT2 "Cad, GALGT2, Sda" ENSG00000167080 "Beta-1,4-N-acetyl-galactosaminyltransferase 2" Q8NHY0 17 49132460-49176840 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 33.5" "Cell type enhanced" "Detected in some" "Collecting duct cells: 5.5;Distal enterocytes: 3.9;Glandular and luminal cells: 5.2;Intestinal goblet cells: 11.5;Ionocytes: 4.1;Proximal enterocytes: 14.8" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 6.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA015721 Approved NA NA "Cluster 9: Intestine - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" "HPA015721: AB_1845245" "unprognostic (4.39e-4)" "unprognostic (3.18e-1)" "unprognostic (8.26e-3)" "unprognostic (2.03e-4)" "unprognostic (1.72e-2)" "unprognostic (2.62e-2)" "unprognostic (3.67e-2)" "unprognostic (7.67e-2)" "unprognostic (4.06e-1)" "unprognostic (7.18e-3)" "unprognostic (2.43e-1)" "prognostic favorable (1.29e-5)" "unprognostic (3.53e-1)" "unprognostic (1.31e-1)" "unprognostic (7.81e-3)" "unprognostic (2.15e-1)" 1.2 1.3 1.4 7.8 1.0 4.7 0.7 6.6 2.1 0.2 2.3 33.5 2.1 1.1 0.6 0.7 0.4 2.2 1.0 1.7 0.8 9.1 0.9 1.4 2.2 0.7 0.4 1.0 1.7 0.1 0.0 0.7 0.5 0.7 14.2 7.5 2.0 0.3 0.8 2.8 8.4 2.7 0.0 2.2 5.9 1.5 1.1 0.2 5.9 0.1 0.8 0.6 0.0 1.5 0.9 1.7 1.7 3.0 0.1 0.0 0.9 1.3 1.0 0.0 0.1 4.0 1.4 2.1 2.1 0.0 0.6 0.9 0.7 0.1 0.2 1.8 1.8 2.2 5.1 2.1 0.0 1.1 3.5 0.2 1.4 0.3 0.2 0.7 0.0 1.6 1.3 3.3 0.0 1.1 1.4 1.5 2.1 0.3 0.8 2.5 0.7 0.6 5.4 1.4 1.4 1.5 0.6 0.7 0.6 1.7 1.8 1.4 0.6 2.2 1.3 1.3 0.7 2.6 0.9 2.3 0.7 1.4 0.9 0.3 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 1.4 1.0 6.6 2.1 1.7 0.8 0.7 0.4 0.5 0.0 1.1 1.5 0.0 0.0 1.5 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.1 0.3 0.5 0.0 0.9 5.5 0.0 0.0 0.0 3.9 1.9 0.6 0.7 0.6 0.5 0.1 0.0 0.0 0.4 0.0 0.0 0.1 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 11.5 4.1 0.0 0.0 1.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 14.8 0.1 0.8 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.1 0.0 0.1 0.0 2.1 0.1 B4GALT4 beta4Gal-T4 ENSG00000121578 "Beta-1,4-galactosyltransferase 4" O60513 3 119211732-119240946 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 76.0" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 123.6;Urothelial cells: 171.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ: 125.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046819, HPA063546" Approved Supported "Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 37: Intestine - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Golgi apparatus" "HPA046819: AB_2679824, HPA063546: AB_2685036" "unprognostic (4.07e-2)" "unprognostic (1.78e-2)" "unprognostic (3.27e-2)" "unprognostic (1.14e-3)" "unprognostic (4.59e-2)" "unprognostic (1.20e-1)" "prognostic unfavorable (4.04e-4)" "unprognostic (6.30e-2)" "unprognostic (1.20e-1)" "unprognostic (3.58e-1)" "unprognostic (6.10e-3)" "unprognostic (2.26e-2)" "unprognostic (2.76e-2)" "unprognostic (1.21e-1)" "unprognostic (1.18e-1)" "unprognostic (2.37e-1)" "unprognostic (1.11e-1)" 12.4 9.1 6.8 10.7 8.4 20.1 11.1 6.5 8.1 16.4 8.7 30.6 28.6 14.8 76.0 17.7 21.8 33.2 12.9 7.0 6.9 24.1 16.6 9.9 9.9 6.9 6.7 18.4 19.5 15.1 18.2 25.7 6.9 13.7 35.2 9.9 12.2 14.7 6.3 14.1 32.5 13.6 7.0 9.4 29.3 8.3 7.5 7.4 16.4 6.5 11.5 37.6 10.5 7.2 60.1 100.3 12.8 9.8 36.0 31.1 65.3 125.8 54.4 54.4 56.2 65.4 18.3 11.8 23.9 61.3 32.2 78.6 20.7 15.0 59.9 23.5 6.8 15.1 20.3 31.7 25.3 8.9 15.7 21.2 21.4 23.0 19.3 21.6 5.8 8.0 11.2 11.7 25.5 18.4 5.3 10.7 17.6 34.0 27.2 4.9 11.8 4.7 31.2 60.3 10.9 24.0 29.4 14.6 27.9 28.2 30.2 5.7 4.9 27.3 24.0 15.2 13.5 27.2 21.5 16.1 23.5 10.1 23.5 20.1 4.1 8.3 13.3 5.2 7.3 4.2 7.3 7.9 5.5 3.2 13.6 7.1 2.5 14.8 5.0 3.4 2.7 5.7 6.8 8.4 6.5 8.1 7.0 6.9 6.9 6.7 6.9 7.0 7.5 7.2 8.5 0.0 9.4 7.2 17.1 10.7 22.2 48.9 12.0 10.8 14.9 12.4 9.2 61.5 69.1 7.3 4.2 36.2 46.0 43.2 1.9 30.7 2.1 40.1 16.9 8.4 13.8 7.8 11.9 33.2 123.6 24.0 36.2 74.5 13.3 35.0 3.9 10.8 14.4 18.5 11.1 78.7 16.2 9.8 14.8 2.4 14.9 14.9 14.2 6.5 10.9 22.2 39.1 10.6 10.2 40.5 50.2 28.2 27.4 30.7 59.3 22.6 52.6 10.2 19.7 13.9 16.9 1.7 8.4 14.0 10.5 52.3 23.1 20.0 23.6 171.6 BACH1 "BACH-1, BTBD24" ENSG00000156273 "BTB domain and CNC homolog 1" O14867 21 29194071-29630751 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 89.4" "Cell type enhanced" "Detected in all" "Early spermatids: 164.4;Late spermatids: 422.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 150.2" "Group enriched" "Detected in all" 4 "granulocytes: 150.2;monocytes: 51.1" "Cell line enhanced" "Detected in all" "Karpas-707: 129.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034949 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm Cytosol "HPA034949: AB_2674376" "unprognostic (1.57e-1)" "unprognostic (8.08e-3)" "unprognostic (2.64e-1)" "unprognostic (2.33e-2)" "unprognostic (6.00e-2)" "unprognostic (2.99e-1)" "unprognostic (9.84e-3)" "unprognostic (1.20e-3)" "unprognostic (5.76e-2)" "unprognostic (5.79e-3)" "prognostic unfavorable (3.11e-5)" "unprognostic (5.63e-2)" "prognostic unfavorable (7.14e-4)" "unprognostic (2.59e-1)" "unprognostic (1.60e-1)" "unprognostic (4.19e-2)" "unprognostic (8.70e-2)" 15.8 12.1 12.3 27.8 13.3 89.4 13.3 27.6 16.0 18.1 9.9 13.4 17.4 19.8 9.7 23.0 9.1 26.1 13.2 10.5 19.5 16.0 30.5 21.4 16.9 23.0 28.4 11.6 17.2 8.3 3.3 50.6 31.0 13.3 13.2 12.0 17.4 8.6 26.3 23.3 17.4 15.9 14.2 20.7 13.5 27.3 16.6 14.2 12.6 12.8 14.8 29.8 13.1 12.3 21.5 8.6 26.1 6.8 20.2 57.7 16.3 23.0 55.0 21.8 24.3 18.1 28.9 25.5 18.0 21.1 22.7 11.1 15.7 30.9 38.6 21.3 13.3 78.7 18.9 18.6 26.8 22.8 28.1 30.3 46.4 42.8 63.4 25.7 11.7 13.9 40.6 129.7 30.2 7.6 19.5 13.0 40.3 8.4 8.9 19.8 61.8 33.1 11.5 16.8 10.8 12.2 12.6 23.5 29.0 26.0 17.1 27.1 29.6 21.3 29.4 23.1 11.8 74.9 51.9 26.9 17.3 27.8 64.9 72.4 51.1 38.6 5.0 40.1 4.1 10.3 8.3 4.3 24.9 13.7 11.9 6.0 150.2 7.1 46.0 6.0 14.8 15.3 12.3 13.3 27.6 16.0 10.5 19.5 23.0 28.4 31.0 14.2 16.6 12.3 31.9 28.9 15.3 12.1 90.6 59.0 53.2 17.9 19.4 16.6 18.3 15.1 20.7 15.7 23.1 14.7 18.8 13.7 33.0 30.7 7.9 19.8 164.4 32.2 45.9 26.0 30.9 33.0 5.1 16.6 15.7 31.3 30.5 64.1 48.6 13.6 22.1 20.9 22.0 13.5 36.9 24.7 12.2 57.1 113.8 422.4 13.4 113.8 21.4 68.4 109.1 10.2 24.7 33.7 25.0 28.2 38.2 14.3 87.8 50.7 25.5 12.8 15.7 12.6 32.9 54.7 36.6 31.5 28.4 34.7 58.1 39.7 31.3 17.4 11.7 48.4 BAG1 ENSG00000107262 "BAG cochaperone 1" Q99933 9 33247820-33264720 "Cancer-related genes, Predicted intracellular proteins" Apoptosis Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 1043.2;Late spermatids: 2944.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HeLa: 437.5;NB-4: 417.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002486, HPA018121, HPA073236" Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 34: Spermatids - Unknown function" Nucleoplasm Cytosol "CAB002486: AB_563422, HPA018121: AB_1845255, HPA073236: " "unprognostic (4.49e-3)" "unprognostic (4.52e-2)" "unprognostic (2.33e-2)" "unprognostic (1.32e-3)" "unprognostic (5.46e-2)" "unprognostic (3.67e-3)" "unprognostic (2.10e-1)" "unprognostic (1.34e-2)" "unprognostic (4.62e-2)" "unprognostic (7.21e-2)" "unprognostic (4.24e-1)" "unprognostic (2.23e-1)" "prognostic favorable (2.22e-16)" "unprognostic (4.45e-2)" "unprognostic (4.03e-1)" "unprognostic (7.64e-3)" "unprognostic (1.07e-2)" 79.7 76.3 96.6 36.3 106.7 85.0 72.3 102.2 112.3 65.0 106.0 122.5 59.3 59.8 53.9 103.2 54.8 39.1 192.9 86.4 102.8 151.6 83.4 82.5 35.5 107.4 105.2 45.6 91.7 139.6 99.3 47.1 98.8 88.0 75.4 82.2 97.4 68.4 297.7 113.8 66.1 42.7 100.2 66.0 102.5 87.9 104.3 45.1 71.6 206.1 55.2 121.5 78.8 101.6 56.0 56.1 46.8 103.3 69.9 40.9 63.6 46.5 64.6 68.4 69.8 39.7 54.1 181.2 33.6 46.6 24.5 69.8 54.8 37.9 45.0 96.5 52.1 90.2 437.5 62.5 58.9 210.1 110.0 41.5 205.6 32.3 76.8 32.2 82.4 48.0 108.7 92.1 57.8 89.7 152.4 417.0 90.8 73.9 81.2 78.7 63.7 119.6 87.1 164.8 149.1 88.5 192.7 176.9 46.0 18.7 80.5 261.8 44.1 30.5 37.8 89.9 78.0 74.9 125.3 100.4 25.5 114.1 17.7 29.1 20.7 57.9 10.0 22.2 9.0 14.7 11.2 11.9 26.1 25.6 15.7 9.1 10.2 15.3 22.3 33.9 15.2 10.2 96.6 106.7 102.2 112.3 86.4 102.8 107.4 105.2 98.8 100.2 104.3 101.6 107.7 89.8 67.5 5.2 69.4 429.9 279.4 193.3 172.4 84.0 134.1 123.6 144.4 127.2 157.0 218.8 58.4 154.7 113.7 211.4 397.2 135.6 1043.2 109.3 72.2 86.6 198.1 259.1 5.9 189.0 59.9 79.4 104.5 193.3 41.9 36.7 66.8 72.8 104.9 38.7 7.1 287.8 170.9 86.4 162.7 2944.9 85.7 93.9 163.7 2.8 81.0 123.9 88.6 4.5 9.7 131.1 259.2 88.8 110.3 505.4 247.9 286.1 71.8 131.3 98.6 98.5 109.9 87.9 64.4 261.1 561.5 245.9 69.6 103.7 222.4 531.4 BARD1 ENSG00000138376 "BRCA1 associated RING domain 1" Q99728 2 214725646-214809683 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 68.6;Basal prostatic cells: 62.2;Suprabasal keratinocytes: 74.4;Urothelial cells: 67.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB034106, HPA035354, HPA044864" Enhanced Supported "Nucleoplasm,Nuclear speckles,Cytoplasmic bodies" No Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Nuclear speckles" "Cytoplasmic bodies" "CAB034106: AB_2061237, HPA035354: AB_2674585, HPA044864: AB_2679119" "unprognostic (4.85e-2)" "unprognostic (1.87e-2)" "unprognostic (1.74e-2)" "unprognostic (8.37e-3)" "unprognostic (2.57e-2)" "unprognostic (1.03e-2)" "unprognostic (6.25e-4)" "unprognostic (1.99e-1)" "unprognostic (2.16e-2)" "unprognostic (3.92e-3)" "unprognostic (2.80e-2)" "unprognostic (7.41e-2)" "unprognostic (1.94e-8)" "unprognostic (3.94e-2)" "unprognostic (2.28e-1)" "unprognostic (1.57e-1)" "unprognostic (1.08e-1)" 1.8 0.6 3.0 2.7 4.6 11.4 2.9 2.2 2.7 3.1 0.2 2.9 2.3 3.3 2.6 5.1 1.9 2.0 1.5 2.3 4.1 0.8 1.0 2.5 5.5 3.8 3.2 2.3 1.6 2.3 1.2 2.3 3.9 2.9 3.6 2.0 1.9 3.6 4.2 8.8 2.1 3.9 3.9 2.6 1.9 6.6 4.1 7.0 1.4 2.3 6.6 2.1 3.8 4.2 12.3 8.8 20.2 9.3 2.7 4.0 12.0 17.3 10.6 17.8 21.8 12.0 12.2 12.6 7.6 8.5 9.5 12.7 16.5 10.5 22.7 11.5 6.4 12.5 13.8 8.7 0.9 13.9 12.7 4.7 1.1 15.0 8.1 4.5 6.1 14.7 7.9 36.0 13.7 10.7 27.9 12.5 14.3 7.9 3.7 24.7 19.8 11.2 3.9 14.0 5.8 8.8 15.0 14.7 5.3 10.9 16.3 13.4 4.7 18.0 14.0 11.7 13.6 10.2 12.6 28.0 7.6 11.3 13.4 3.9 2.0 5.8 4.6 4.0 3.2 9.7 5.4 5.5 3.6 8.2 2.4 4.0 0.3 7.3 3.8 6.9 17.1 2.3 3.0 4.6 2.2 2.7 2.3 4.1 3.8 3.2 3.9 3.9 4.1 4.2 12.3 6.4 2.2 14.7 13.0 68.6 62.2 13.0 14.2 3.3 9.9 14.1 17.4 17.2 12.7 9.2 0.0 18.2 11.3 8.2 3.9 8.0 9.2 13.3 11.9 9.6 1.2 34.5 5.5 6.9 16.0 10.0 10.2 18.0 15.2 28.2 10.0 4.2 12.5 1.7 15.4 13.1 8.2 10.1 12.2 5.7 6.2 11.2 3.6 15.9 16.6 4.4 9.2 19.6 31.7 6.5 6.5 10.1 22.0 22.9 3.2 0.7 12.3 6.8 19.7 15.4 16.9 27.6 43.4 28.6 74.4 5.1 13.4 10.5 14.7 67.2 BARX2 ENSG00000043039 "BARX homeobox 2" Q9UMQ3 11 129375848-129452279 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 158.0;salivary gland: 131.4;vagina: 72.2" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 128.5;Breast glandular cells: 50.4;Squamous epithelial cells: 136.4;Suprabasal keratinocytes: 82.5;Urothelial cells: 84.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "HDLM-2: 163.7" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "cerebral cortex: 2.8;hippocampal formation: 1.7" "CAB033311, HPA064966, HPA068414" Enhanced Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 44: HDLM-2 - Immune response" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "Golgi apparatus, Cytosol" "CAB033311: AB_781574, HPA064966: , HPA068414: AB_2685984" "unprognostic (4.25e-2)" "unprognostic (2.89e-1)" "unprognostic (2.46e-1)" "unprognostic (1.22e-5)" "unprognostic (3.85e-2)" "unprognostic (9.29e-2)" "unprognostic (1.57e-1)" "unprognostic (1.43e-3)" "unprognostic (4.80e-1)" "unprognostic (1.71e-2)" "unprognostic (4.35e-3)" "unprognostic (1.15e-1)" "unprognostic (8.39e-2)" "unprognostic (3.48e-1)" "unprognostic (8.37e-2)" "unprognostic (2.14e-2)" "prognostic unfavorable (3.06e-4)" 0.3 0.0 0.1 1.3 0.3 0.0 14.9 1.1 0.3 24.2 5.5 7.0 17.9 0.1 0.2 158.0 16.7 4.7 0.2 0.3 0.4 5.4 0.0 0.3 0.7 3.0 1.6 0.0 10.3 0.3 1.7 3.6 3.2 4.8 4.9 0.2 131.4 0.6 2.2 34.8 13.0 0.2 1.8 0.0 6.4 2.4 0.4 0.4 0.3 39.3 8.8 0.4 72.2 2.9 23.7 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.3 0.0 1.0 20.9 0.0 5.1 0.0 163.7 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 7.1 0.0 3.9 0.0 6.2 0.0 0.0 0.0 20.6 0.9 0.0 0.0 39.8 0.0 0.3 0.2 0.0 0.0 19.4 0.1 0.4 3.8 0.1 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 1.1 0.3 0.3 0.4 3.0 1.6 3.2 1.8 0.4 2.9 0.2 0.0 1.1 0.3 0.5 43.1 128.5 8.7 3.4 0.6 50.4 16.9 0.5 4.3 8.0 0.0 0.0 13.4 0.8 29.4 7.9 23.7 7.2 11.3 0.6 1.2 1.8 0.0 1.8 0.7 5.8 2.7 6.6 4.6 0.0 0.0 0.0 0.2 1.9 0.0 0.3 13.4 0.0 0.3 2.2 1.6 0.0 0.7 10.6 0.0 0.1 0.7 0.0 0.0 0.3 6.2 29.8 0.4 0.9 25.6 34.0 3.4 11.8 0.3 0.0 0.6 1.7 0.1 5.3 136.4 82.5 4.2 1.7 0.0 19.4 84.8 BCAN "BEHAB, CSPG7, MGC13038" ENSG00000132692 Brevican Q96GW7 1 156641390-156659532 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 164.7" "Group enriched" "Detected in some" 8 "Astrocytes: 136.1;Horizontal cells: 109.4;Melanocytes: 186.7;Oligodendrocyte precursor cells: 288.0" "Cancer enriched" "Detected in many" 5 "glioma: 348.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 24 "basophil: 7.8" "Lineage enriched" "Detected in single" 24 "granulocytes: 7.8" "Cell line enhanced" "Detected in many" "HDLM-2: 76.7;K-562: 108.3;U-266/70: 63.3;U-266/84: 133.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007865, CAB025862" Enhanced Supported "Secreted in brain" NA NA 120000 "Cluster 34: Basophils - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 16: U-266 - Nucleosome" "Cluster 68: Oligodendrocytes - Mixed function" "CAB025862: , HPA007865: AB_1078299" "unprognostic (7.14e-2)" "unprognostic (3.14e-1)" "unprognostic (1.95e-2)" "unprognostic (1.90e-1)" "unprognostic (1.04e-1)" "unprognostic (9.03e-2)" "unprognostic (4.58e-2)" "unprognostic (2.02e-2)" "unprognostic (4.80e-2)" "unprognostic (6.87e-2)" "unprognostic (1.65e-1)" "unprognostic (1.30e-2)" "unprognostic (9.47e-3)" "unprognostic (2.76e-2)" "unprognostic (8.54e-2)" "unprognostic (5.40e-1)" "unprognostic (1.90e-1)" 0.2 8.4 155.0 0.6 119.5 0.0 0.2 108.3 164.7 2.7 38.3 2.2 7.0 5.9 15.4 0.6 4.0 3.4 0.5 133.1 104.8 0.2 0.1 0.4 0.3 107.5 100.0 0.2 0.1 1.7 2.8 0.7 103.4 0.2 0.0 4.1 1.6 1.8 0.6 15.6 7.8 2.0 94.3 0.5 2.2 1.2 113.7 0.1 0.2 0.0 0.0 0.9 0.9 116.3 44.2 28.4 0.2 8.1 0.0 0.0 11.9 0.4 0.0 0.0 0.0 1.1 21.0 0.1 45.8 0.0 1.0 30.9 0.3 0.0 0.0 76.7 2.9 8.0 20.9 25.6 0.0 3.0 7.3 0.0 0.0 0.0 0.0 1.0 0.0 3.8 108.3 21.0 0.0 12.6 0.1 0.1 2.2 22.2 4.2 0.1 46.7 0.1 0.0 5.4 0.2 0.8 0.1 0.0 43.8 2.2 0.2 2.8 8.8 0.1 24.7 8.7 11.8 63.3 133.2 0.2 8.5 20.4 3.4 7.8 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 155.0 119.5 108.3 164.7 133.1 104.8 107.5 100.0 103.4 94.3 113.7 116.3 0.2 0.0 0.0 136.1 0.0 6.9 0.0 0.0 0.0 6.0 0.2 0.6 1.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.1 2.9 0.1 1.8 0.7 1.8 0.0 16.8 0.2 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.5 109.4 20.2 0.1 0.0 0.0 1.9 6.9 0.3 0.1 186.7 9.4 0.0 2.1 1.0 288.0 3.5 0.8 0.1 0.0 0.0 0.3 0.1 0.4 0.0 3.2 0.0 0.2 1.7 5.4 6.5 0.0 1.7 0.0 0.2 0.0 0.0 0.0 BCL11A "BCL11A-L, BCL11A-S, BCL11A-XL, CTIP1, EVI9, HBFQTL5, ZNF856" ENSG00000119866 "BAF chromatin remodeling complex subunit BCL11A" Q9H165 2 60450520-60554467 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Repressor "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 47.8;lymphoid tissue: 40.9" "Cell type enhanced" "Detected in many" "B-cells: 149.0;Basal squamous epithelial cells: 118.4;dendritic cells: 140.3;Excitatory neurons: 180.8;Inhibitory neurons: 153.2;Squamous epithelial cells: 120.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "memory B-cell: 312.7;naive B-cell: 415.7;plasmacytoid DC: 899.0" "Group enriched" "Detected in all" 15 "B-cells: 415.7;dendritic cells: 899.0" "Cell line enhanced" "Detected in many" "Daudi: 51.1;MOLT-4: 49.0;REH: 48.3;U-698: 106.7;U-937: 34.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basal ganglia: 52.5;cerebral cortex: 82.3;hippocampal formation: 69.2;olfactory bulb: 66.7" "CAB014891, HPA029003, HPA075941" Enhanced Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "Nuclear bodies" "CAB014891: , HPA029003: AB_2672863, HPA075941: " "unprognostic (4.10e-3)" "unprognostic (6.72e-2)" "unprognostic (4.50e-2)" "unprognostic (9.41e-3)" "unprognostic (2.37e-1)" "unprognostic (4.47e-3)" "unprognostic (2.53e-2)" "unprognostic (1.68e-2)" "unprognostic (1.02e-1)" "unprognostic (2.45e-1)" "unprognostic (4.27e-4)" "unprognostic (1.23e-2)" "unprognostic (2.35e-2)" "unprognostic (3.59e-2)" "unprognostic (2.26e-1)" "unprognostic (4.40e-2)" "unprognostic (2.99e-2)" 0.7 2.1 31.4 11.3 34.7 25.3 7.1 10.5 47.8 5.2 9.7 18.4 9.7 2.1 1.4 18.4 5.7 2.5 8.0 38.7 15.5 1.0 0.5 2.1 29.2 31.6 15.3 0.6 10.8 1.7 3.0 0.9 31.0 7.8 6.1 1.7 13.8 1.9 1.7 33.2 13.9 3.4 15.9 19.6 4.8 2.0 15.9 33.9 2.3 0.2 40.9 3.3 11.5 38.7 0.6 0.0 4.2 0.1 0.8 0.8 0.3 1.5 0.0 0.1 0.0 0.0 0.2 51.1 0.2 0.2 0.0 10.5 15.4 7.4 0.2 0.9 15.2 0.1 0.6 0.2 0.0 18.7 0.1 1.7 4.1 0.0 2.5 4.0 2.6 17.1 0.8 0.3 0.1 0.1 49.0 19.9 28.6 7.7 0.2 48.3 1.3 19.7 0.0 0.9 20.1 4.8 0.3 0.4 0.3 8.0 0.3 9.1 1.0 0.3 11.6 0.3 0.1 0.8 0.2 106.7 0.1 34.0 1.6 4.5 23.8 5.1 0.5 44.1 1.1 312.7 0.5 0.5 89.9 415.7 1.3 1.1 11.0 8.4 33.7 899.0 1.1 11.4 31.4 34.7 10.5 47.8 38.7 15.5 31.6 15.3 31.0 15.9 15.9 38.7 0.6 0.0 7.4 3.6 149.0 46.3 16.0 34.0 118.4 2.5 31.6 28.6 18.2 4.3 11.7 1.8 0.0 0.6 140.3 7.5 5.9 9.5 12.0 3.9 2.0 1.4 19.8 69.6 180.8 6.4 0.5 3.6 5.1 4.8 10.1 67.4 0.7 0.1 43.2 52.2 153.2 13.6 6.1 7.0 86.1 5.0 0.3 20.5 16.0 11.2 16.0 0.3 0.0 3.5 4.6 4.7 12.5 0.0 6.0 11.7 16.2 0.5 5.5 0.3 0.0 0.2 2.0 2.9 6.9 120.3 69.9 0.8 4.6 1.0 28.9 5.8 BFSP1 "CP115, CP94, filensin, LIFL-H" ENSG00000125864 "Beaded filament structural protein 1" Q12934 20 17493905-17569220 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Eye lens protein" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late spermatids: 5.7;NK-cells: 17.5;Spermatogonia: 11.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 2.5" "Lineage enhanced" "Detected in single" "T-cells: 2.5" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 10.8;RPTEC TERT1: 19.5;SK-BR-3: 10.6" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "amygdala: 2.5;cerebral cortex: 3.2;hippocampal formation: 3.6" "HPA040748, HPA042038" Enhanced Supported "Plasma membrane,Cytosol" No No "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 43: Testis - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Plasma membrane, Cytosol" "HPA040748: AB_10963786, HPA042038: AB_10964054" "unprognostic (2.24e-3)" "unprognostic (1.99e-1)" "unprognostic (1.63e-1)" "prognostic favorable (1.39e-4)" "unprognostic (1.07e-2)" "unprognostic (2.21e-1)" "unprognostic (1.22e-6)" "unprognostic (5.11e-2)" "unprognostic (5.53e-1)" "unprognostic (2.10e-4)" "unprognostic (1.75e-1)" "unprognostic (8.81e-2)" "unprognostic (3.35e-4)" "unprognostic (4.45e-2)" "unprognostic (2.73e-2)" "unprognostic (1.78e-2)" "unprognostic (7.50e-2)" 1.1 1.3 2.0 0.5 2.2 0.4 1.1 1.6 2.1 1.3 2.0 1.3 0.3 1.8 1.4 1.1 1.3 1.3 0.7 2.2 2.1 3.7 0.3 1.7 0.3 1.7 1.8 1.5 1.9 1.0 0.9 1.9 1.8 1.2 0.5 0.4 1.5 1.1 0.3 1.0 0.7 1.1 1.5 0.4 0.9 3.8 2.1 0.2 2.5 0.4 0.3 1.3 0.9 2.4 0.8 8.1 2.6 0.3 0.7 2.6 0.4 2.0 9.5 1.3 1.2 3.7 7.0 0.0 1.6 1.2 5.1 1.2 2.8 1.6 1.0 1.8 2.1 0.6 1.2 1.1 1.5 0.5 0.9 3.1 4.9 0.7 2.3 10.8 5.7 0.5 0.3 0.4 4.2 1.6 0.0 1.2 6.1 5.2 2.2 0.0 1.8 0.4 19.5 1.5 2.7 0.3 2.4 10.6 4.3 1.2 5.2 1.8 6.5 0.3 0.6 0.7 2.0 0.0 0.1 0.0 1.4 0.0 1.6 0.0 0.0 0.0 2.5 0.0 0.1 0.0 0.6 0.4 0.0 0.0 0.0 0.2 0.3 0.7 0.0 0.0 0.0 0.2 2.0 2.2 1.6 2.1 2.2 2.1 1.7 1.8 1.8 1.5 2.1 2.4 3.8 3.2 1.7 0.7 0.0 0.9 0.5 0.7 0.0 0.2 1.9 1.5 1.2 1.5 0.4 0.0 0.0 1.2 2.6 0.1 1.9 0.8 1.3 1.1 0.4 3.1 0.0 0.8 2.1 0.9 1.7 1.2 1.5 0.6 0.0 0.2 3.9 0.2 0.5 0.0 1.2 0.2 0.0 0.0 0.8 5.7 1.8 0.2 1.8 2.8 0.0 1.0 17.5 0.5 1.1 0.8 0.0 0.0 0.4 0.4 0.0 0.3 1.8 0.1 0.0 0.5 1.0 1.1 11.9 1.1 0.9 0.4 1.0 0.4 0.3 0.5 BRCA1 "BRCC1, FANCS, PPP1R53, RNF53" ENSG00000012048 "BRCA1 DNA repair associated" P38398 17 43044295-43170245 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA recombination, DNA repair, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, DNA-binding, Transferase" "Cancer-related genes, Disease variant, Fanconi anemia, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 42.5;Granulosa cells: 38.2;Spermatocytes: 105.8;Spermatogonia: 73.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 6.8;classical monocyte: 14.7;intermediate monocyte: 4.7;myeloid DC: 10.9;neutrophil: 11.3" "Group enriched" "Detected in all" 6 "dendritic cells: 10.9;granulocytes: 11.3;monocytes: 14.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB001946, HPA004840, HPA034966, HPA057371" Approved Supported "Nucleoplasm,Nuclear bodies" NA Yes "Cluster 25: Monocytes - Inflammatory response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nuclear bodies" "CAB001946: , HPA004840: , HPA034966: AB_10795287, HPA057371: AB_2732611" "unprognostic (7.87e-3)" "unprognostic (6.97e-2)" "unprognostic (3.53e-3)" "unprognostic (2.39e-1)" "unprognostic (5.42e-2)" "unprognostic (7.07e-3)" "unprognostic (1.56e-3)" "unprognostic (4.14e-3)" "unprognostic (9.62e-3)" "unprognostic (2.47e-1)" "unprognostic (5.53e-3)" "unprognostic (1.28e-1)" "unprognostic (1.08e-4)" "unprognostic (1.08e-3)" "unprognostic (1.48e-1)" "unprognostic (2.12e-1)" "unprognostic (8.31e-2)" 3.1 1.8 4.2 7.5 7.2 13.0 3.6 4.7 5.2 2.7 2.7 6.8 3.2 3.1 2.2 4.0 3.7 1.9 3.0 3.6 4.1 2.0 5.6 3.2 10.3 5.6 5.0 2.8 2.8 5.9 2.8 3.8 6.0 2.4 7.4 8.2 3.2 1.6 4.2 6.0 5.1 3.9 3.7 3.9 3.6 13.0 5.5 14.5 7.8 3.7 11.2 2.8 2.4 10.8 44.1 69.1 37.8 30.1 6.0 13.4 36.6 50.6 21.5 41.9 39.3 42.3 33.4 100.8 9.1 19.0 49.0 49.5 51.9 28.3 69.5 46.9 38.0 48.1 54.0 37.1 1.3 86.0 39.9 3.8 4.5 63.1 20.0 10.6 22.3 46.6 73.7 42.2 39.7 30.0 72.0 27.8 20.5 29.1 18.7 49.0 79.8 40.8 15.4 42.1 25.8 27.4 38.8 12.5 19.4 25.5 33.9 39.6 13.8 37.2 29.6 49.0 53.2 20.1 51.2 75.5 29.6 49.6 39.4 6.8 14.7 2.2 1.5 4.7 1.5 1.2 1.5 1.2 10.9 2.1 1.3 1.5 11.3 1.5 2.0 1.7 0.5 17.5 4.2 7.2 4.7 5.2 3.6 4.1 5.6 5.0 6.0 3.7 5.5 10.8 5.0 0.0 2.8 9.4 5.8 2.9 4.5 1.9 1.2 10.3 4.4 5.2 10.1 5.7 3.5 1.8 22.9 12.8 8.1 6.2 0.0 3.0 11.9 14.0 6.3 4.7 0.0 42.5 3.0 1.1 18.2 7.4 6.1 4.2 8.2 38.2 5.3 18.3 10.1 11.8 4.4 7.5 0.0 3.9 2.8 8.0 2.5 6.4 0.0 4.7 4.9 2.4 5.2 3.0 18.7 1.7 2.4 1.5 16.6 2.3 1.1 1.0 10.0 22.8 6.6 13.7 5.5 105.8 73.5 8.2 2.3 4.0 4.7 9.7 12.7 3.4 BTBD11 "ABTB2B, FLJ33957" ENSG00000151136 "BTB domain containing 11" A6QL63 12 107318421-107659642 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 100.3" "Cell type enriched" "Detected in many" 9 "Inhibitory neurons: 266.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 3.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A549: 25.0;Hep G2: 13.6;MOLT-4: 17.9;PC-3: 12.3;RT4: 11.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055898, HPA061334" Supported Nucleoplasm,Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm Cytosol "HPA055898: AB_2682964, HPA061334: " "unprognostic (3.40e-2)" "unprognostic (4.06e-1)" "unprognostic (2.37e-1)" "unprognostic (7.85e-2)" "unprognostic (8.78e-3)" "unprognostic (4.82e-2)" "unprognostic (3.52e-1)" "unprognostic (2.12e-1)" "unprognostic (1.52e-1)" "unprognostic (5.92e-2)" "unprognostic (5.33e-2)" "unprognostic (1.78e-1)" "unprognostic (4.92e-8)" "unprognostic (2.66e-1)" "unprognostic (1.55e-1)" "unprognostic (3.33e-2)" "unprognostic (9.07e-3)" 0.4 0.7 7.2 2.7 4.3 4.4 2.9 5.5 10.9 8.1 5.9 0.6 0.7 0.9 1.2 29.4 0.3 0.9 0.6 2.9 13.2 4.2 1.1 0.6 2.9 24.3 16.0 0.1 0.8 100.3 3.5 2.0 24.4 3.4 0.6 1.9 5.6 1.3 0.5 11.1 1.4 0.5 11.4 1.4 0.6 0.7 21.7 17.2 18.9 0.2 3.3 1.7 11.1 5.3 0.1 25.0 5.0 0.0 1.8 0.5 0.0 0.6 0.0 0.2 0.0 0.3 4.0 0.0 6.1 0.1 2.4 9.2 5.1 9.5 0.3 0.0 1.6 0.0 0.1 13.6 0.0 0.2 0.1 2.0 4.0 0.0 2.9 3.8 0.7 10.5 0.0 0.0 0.2 0.9 17.9 2.0 5.3 0.5 12.3 0.0 8.1 0.0 0.0 11.4 6.8 2.5 0.0 0.2 0.0 0.4 0.5 0.7 1.0 0.1 0.2 0.0 2.0 0.1 0.0 0.1 6.4 2.6 0.0 0.9 0.4 0.5 1.0 0.1 3.5 0.0 1.1 0.6 0.7 0.1 1.4 1.3 1.3 0.1 0.3 0.1 0.6 0.6 7.2 4.3 5.5 10.9 2.9 13.2 24.3 16.0 24.4 11.4 21.7 5.3 0.3 0.0 0.0 17.3 0.3 5.2 3.7 2.5 6.8 3.5 0.7 3.2 2.9 0.0 3.0 0.0 0.0 0.2 1.2 0.0 0.0 0.8 0.0 1.2 1.9 0.3 3.5 1.3 8.7 0.0 0.0 1.5 0.0 2.3 0.0 0.0 0.0 0.9 0.3 1.7 266.4 0.4 0.0 0.6 4.3 0.0 0.6 1.7 0.0 1.0 1.8 0.2 3.1 12.5 1.9 0.3 0.0 4.1 0.7 2.8 0.2 0.9 0.3 0.4 0.0 0.0 1.1 0.1 0.2 27.5 7.7 0.4 4.5 3.4 0.4 3.4 BTBD16 "C10orf87, Em:AC061711.1, FLJ25359" ENSG00000138152 "BTB domain containing 16" Q32M84 10 122271296-122338159 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skin 1: 8.3;testis: 7.8;urinary bladder: 20.2" "Group enriched" "Detected in some" 9 "Early spermatids: 123.2;Late spermatids: 69.9" "Cancer enriched" "Detected in many" 14 "urothelial cancer: 18.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "RT4: 33.7" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA040529, HPA057638" Uncertain Uncertain Nucleoli,Cytosol Yes NA "Cluster 35: T-regs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 34: Spermatids - Unknown function" Nucleoli Cytosol "HPA040529: AB_2677022, HPA057638: " "unprognostic (1.41e-4)" "unprognostic (1.33e-1)" "unprognostic (5.97e-2)" "unprognostic (5.98e-3)" "unprognostic (2.08e-1)" "unprognostic (2.09e-3)" "unprognostic (2.88e-1)" "unprognostic (4.54e-2)" "unprognostic (1.76e-1)" "unprognostic (6.85e-2)" "unprognostic (2.48e-2)" "unprognostic (1.77e-1)" "prognostic unfavorable (1.50e-4)" "unprognostic (1.08e-1)" "unprognostic (1.60e-1)" "unprognostic (9.12e-2)" "unprognostic (9.44e-3)" 0.1 0.0 1.0 0.0 1.4 0.0 0.5 1.2 2.3 0.3 0.7 0.5 0.0 0.1 0.3 0.1 0.4 0.2 0.0 1.1 1.2 0.3 4.0 0.2 0.0 1.4 1.4 0.0 0.1 0.0 0.4 0.1 1.4 0.8 0.0 0.0 0.4 0.0 0.3 8.3 0.1 0.1 1.3 0.0 0.1 7.8 1.2 0.0 0.4 0.0 0.1 20.2 0.5 2.1 0.0 0.3 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.3 0.0 0.5 0.0 0.1 0.0 0.0 0.1 4.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.4 0.0 1.5 33.7 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.0 1.4 1.2 2.3 1.1 1.2 1.4 1.4 1.4 1.3 1.2 2.1 0.0 0.0 0.0 0.0 0.0 2.8 0.4 0.2 0.0 0.0 0.2 0.0 0.6 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 1.4 123.2 0.6 0.0 0.2 0.0 0.0 0.9 0.7 0.1 0.0 0.0 0.4 0.0 0.0 0.0 4.5 0.0 0.0 1.2 0.0 0.0 0.0 0.4 69.9 0.6 0.0 0.0 1.0 0.0 0.0 0.0 0.5 9.8 1.1 3.8 0.4 0.0 0.1 0.2 1.0 3.1 0.0 0.0 0.4 0.2 10.0 0.8 0.0 3.1 0.1 0.4 0.0 0.0 2.9 BZW2 "HSPC028, MST017, MSTP017" ENSG00000136261 "Basic leucine zipper and W2 domains 2" Q9Y6E2 7 16646131-16706523 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 265.5;skeletal muscle: 367.7;tongue: 258.9" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 278.2;Extravillous trophoblasts: 875.6;Syncytiotrophoblasts: 762.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022813, HPA026709" Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane, Actin filaments, Cytosol" "HPA022813: AB_1845511, HPA026709: AB_10600752" "unprognostic (2.27e-3)" "unprognostic (1.77e-3)" "unprognostic (5.91e-2)" "unprognostic (4.79e-3)" "unprognostic (2.80e-2)" "unprognostic (7.08e-3)" "prognostic unfavorable (7.86e-8)" "unprognostic (9.13e-3)" "unprognostic (8.49e-3)" "unprognostic (2.81e-2)" "unprognostic (1.83e-3)" "unprognostic (3.37e-2)" "prognostic unfavorable (6.01e-4)" "unprognostic (1.00e-1)" "unprognostic (1.66e-1)" "unprognostic (6.77e-2)" "unprognostic (1.25e-1)" 26.1 18.1 8.5 26.8 10.1 45.7 49.7 6.9 14.3 19.1 9.7 51.2 28.9 18.4 9.9 42.6 20.2 17.2 265.5 10.2 6.3 37.8 18.4 20.0 30.0 5.2 6.3 16.0 30.0 6.7 10.4 80.4 6.5 19.3 56.8 88.0 23.8 34.3 367.7 55.5 30.0 39.0 5.6 16.5 50.2 11.6 6.9 33.0 36.5 258.9 38.4 59.5 26.2 8.8 91.7 81.3 138.2 201.7 67.5 118.3 125.7 126.0 156.3 117.6 124.9 201.8 129.7 208.0 143.7 96.9 87.6 181.6 164.8 141.5 152.0 27.8 99.8 129.6 84.4 117.0 70.5 180.3 79.1 90.6 74.6 104.0 187.7 92.4 171.6 149.7 251.9 43.5 96.9 105.0 90.0 210.4 143.9 259.5 174.1 111.0 91.2 216.6 113.4 152.6 179.9 106.8 50.8 419.9 67.7 156.7 187.8 149.5 97.6 93.1 119.1 141.5 136.3 89.5 92.8 288.1 45.5 220.6 340.3 2.6 46.0 5.0 27.3 55.2 44.6 44.6 39.8 36.9 98.8 42.9 56.8 47.1 2.1 56.8 41.6 38.5 31.8 44.0 8.5 10.1 6.9 14.3 10.2 6.3 5.2 6.3 6.5 5.6 6.9 8.8 32.8 22.4 60.5 3.9 30.0 57.6 69.9 60.5 82.6 55.9 52.3 57.0 278.2 17.2 53.9 47.8 64.6 214.3 26.8 42.4 58.7 47.5 9.8 31.9 43.2 42.9 30.5 63.5 48.6 65.6 875.6 43.5 110.1 40.6 21.0 33.3 8.9 13.7 65.0 6.7 32.0 49.5 61.1 33.4 46.0 6.4 12.2 30.7 24.9 12.2 47.5 19.7 19.6 19.1 17.9 47.0 42.9 9.8 31.9 52.0 19.2 20.8 32.6 106.4 6.6 30.2 54.2 11.3 4.1 99.6 51.6 762.9 29.3 52.6 90.6 79.0 C12orf66 FLJ32549 ENSG00000174206 "Chromosome 12 open reading frame 66" Q96MD2 12 64186316-64222296 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046743, HPA052855" Uncertain Supported "Lysosomes,Cytokinetic bridge" Yes No "Cluster 30: Non-specific - Translation" "Cluster 35: Non-specific - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 57: B-cells - Immune response" Lysosomes "Cytokinetic bridge" "HPA046743: AB_2679782, HPA052855: AB_2681973" "unprognostic (7.44e-3)" "unprognostic (2.38e-1)" "unprognostic (6.20e-2)" "unprognostic (2.70e-1)" "unprognostic (2.31e-1)" "unprognostic (4.62e-2)" "unprognostic (3.45e-2)" "unprognostic (2.08e-1)" "unprognostic (1.15e-1)" "unprognostic (2.94e-1)" "unprognostic (1.93e-1)" "unprognostic (3.60e-1)" "unprognostic (1.22e-1)" "unprognostic (1.57e-1)" "unprognostic (1.10e-1)" "unprognostic (7.46e-2)" "unprognostic (4.07e-2)" 2.9 4.2 3.6 3.4 5.3 1.7 5.4 4.0 4.8 2.8 1.9 2.8 3.1 2.6 4.8 4.2 3.9 2.5 2.3 3.5 4.3 5.5 8.6 2.8 4.9 4.0 4.4 3.9 5.2 5.7 2.6 2.1 4.5 2.3 3.1 1.6 2.9 2.3 4.4 5.6 2.5 2.3 3.7 5.0 3.0 3.4 4.3 3.3 5.6 3.2 4.8 2.6 3.0 6.8 5.5 8.7 1.6 4.7 4.3 7.2 4.5 3.0 3.7 4.4 2.7 2.7 4.3 17.4 4.1 2.4 7.1 6.3 6.9 5.3 4.7 13.3 4.6 6.3 2.1 2.5 5.6 6.9 3.6 5.6 9.0 5.7 10.3 5.0 3.2 12.0 8.8 11.3 4.4 10.6 7.9 6.0 7.7 6.5 6.8 4.0 4.9 13.4 6.6 6.4 3.8 3.8 4.9 6.7 4.8 4.2 10.8 4.4 2.5 4.4 2.9 4.4 2.9 14.9 13.2 9.7 6.6 5.9 5.0 0.5 2.6 0.2 3.3 2.6 5.7 8.5 6.4 5.0 4.3 7.2 8.7 8.4 0.2 4.0 1.8 3.1 10.8 4.2 3.6 5.3 4.0 4.8 3.5 4.3 4.0 4.4 4.5 3.7 4.3 6.8 3.4 3.2 2.7 5.5 9.3 2.4 8.8 3.4 7.4 2.1 5.9 4.1 2.7 7.2 5.5 9.2 2.1 6.3 4.0 1.9 9.8 4.1 9.2 3.3 4.0 3.9 4.2 3.4 7.1 5.2 3.9 3.5 7.1 3.6 1.3 3.6 1.8 10.8 4.9 0.0 5.5 2.7 4.1 6.3 2.6 7.3 4.7 4.3 1.8 1.0 2.1 2.5 1.0 3.5 17.4 2.6 2.6 1.9 2.8 4.7 2.1 12.9 2.4 1.6 0.0 7.4 2.8 4.4 8.8 6.9 4.3 1.8 5.8 4.3 3.7 4.3 C14orf180 "C14orf77, NRAC" ENSG00000184601 "Chromosome 14 open reading frame 180" Q8N912 14 104579764-104590515 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 40.8;breast: 26.7;heart muscle: 109.5" "Cell type enhanced" "Detected in some" "Bipolar cells: 2.7;Cardiomyocytes: 7.6;Fibroblasts: 2.0;Hepatic stellate cells: 3.3;Horizontal cells: 3.3;Smooth muscle cells: 1.4" "Cancer enhanced" "Detected in single" "renal cancer: 0.7" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 24 "ASC diff: 3.4" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (2.48e-2)" "unprognostic (1.55e-1)" "unprognostic (1.53e-1)" "unprognostic (1.57e-1)" "unprognostic (1.60e-1)" "unprognostic (3.19e-3)" "unprognostic (1.89e-1)" "unprognostic (3.12e-2)" "unprognostic (3.89e-2)" "unprognostic (2.32e-1)" "unprognostic (9.80e-2)" 40.8 3.1 0.0 0.1 0.2 0.0 26.7 0.2 0.2 0.9 13.5 0.9 0.3 1.1 0.0 0.0 1.8 0.2 109.5 1.5 0.0 1.8 4.1 0.4 0.0 0.5 0.8 0.8 0.8 0.0 1.8 0.8 0.5 0.6 0.0 0.1 0.9 0.4 5.7 0.6 1.4 0.0 0.0 0.5 2.2 0.1 0.4 0.0 0.9 0.7 0.0 1.1 0.6 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 1.5 0.0 0.5 0.8 0.5 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.4 7.6 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 1.1 0.0 2.0 0.0 0.0 0.0 0.0 3.3 0.0 0.3 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.1 1.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 C1orf122 FLJ45459 ENSG00000197982 "Chromosome 1 open reading frame 122" Q6ZSJ8 1 37806979-37809454 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" "unprognostic (7.83e-2)" "unprognostic (4.07e-3)" "unprognostic (1.46e-1)" "unprognostic (7.79e-3)" "unprognostic (1.66e-1)" "unprognostic (1.39e-1)" "unprognostic (1.45e-3)" "unprognostic (7.12e-2)" "unprognostic (1.69e-1)" "unprognostic (4.44e-2)" "unprognostic (2.81e-3)" "unprognostic (3.89e-1)" "unprognostic (3.58e-2)" "unprognostic (9.64e-2)" "unprognostic (1.65e-1)" "unprognostic (1.90e-2)" "prognostic unfavorable (4.81e-4)" 48.1 85.5 80.5 10.3 87.3 7.6 44.2 86.7 92.3 39.0 77.0 54.3 11.3 40.4 20.2 50.9 36.4 7.5 76.2 74.7 76.4 74.3 82.5 34.8 7.0 90.8 85.3 31.8 63.0 19.7 101.8 10.3 82.7 60.1 8.2 24.9 40.5 18.1 61.1 37.2 33.0 11.2 87.4 32.4 55.5 39.7 87.7 6.7 42.9 21.6 7.1 45.3 37.3 94.9 38.2 19.7 21.3 25.6 35.3 40.3 84.8 43.5 23.5 29.6 25.8 33.7 37.0 20.7 91.5 27.5 22.1 33.9 14.4 30.1 16.8 39.0 48.1 13.9 23.8 20.8 49.9 18.5 24.7 48.9 65.3 23.8 27.5 33.0 20.5 17.6 35.1 21.1 27.4 36.2 19.4 32.4 57.6 30.7 50.0 29.2 20.9 43.5 30.9 19.4 39.3 63.8 31.5 30.8 38.8 37.6 40.3 11.8 24.9 37.1 33.4 20.9 40.8 49.4 26.7 24.8 33.5 20.5 29.2 1.4 4.9 5.8 3.7 5.8 1.7 1.2 2.5 2.2 3.6 2.9 1.5 2.4 3.0 3.1 5.6 2.5 2.7 2.9 80.5 87.3 86.7 92.3 74.7 76.4 90.8 85.3 82.7 87.4 87.7 94.9 57.4 3.2 14.0 37.9 38.5 55.4 95.5 45.9 51.2 146.1 101.4 95.4 83.3 60.1 30.8 82.8 41.7 84.5 47.9 105.4 266.1 59.6 11.5 62.5 60.5 57.5 113.6 10.8 19.0 109.9 132.4 80.4 31.1 124.8 34.3 67.9 61.8 127.3 146.3 69.0 23.2 73.7 95.6 52.0 56.5 30.2 49.0 80.1 83.6 9.4 94.3 246.5 41.2 15.1 108.2 71.1 88.0 73.7 51.6 201.6 64.6 274.4 25.2 145.0 32.9 55.2 99.8 24.2 19.6 50.2 60.1 106.7 39.2 126.0 57.8 147.8 C1QC C1QG ENSG00000159189 "Complement C1q C chain" P02747 1 22643633-22648110 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 950.7" "Group enriched" "Detected in many" 7 "Hofbauer cells: 1356.5;Kupffer cells: 2134.6;Macrophages: 1040.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "intermediate monocyte: 57.2" "Lineage enriched" "Detected in single" 541 "monocytes: 57.2" "Cell line enhanced" "Detected in some" "NB-4: 1.0;RPMI-8226: 2.6;U-266/70: 1.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001471, CAB009828" Supported "Secreted to blood" NA NA 513000000 2100000000 "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" "CAB009828: AB_2067541, HPA001471: AB_1078553" "unprognostic (2.97e-1)" "unprognostic (6.80e-2)" "unprognostic (2.40e-2)" "unprognostic (1.84e-1)" "unprognostic (7.40e-2)" "unprognostic (2.38e-1)" "unprognostic (1.98e-1)" "unprognostic (1.40e-1)" "unprognostic (1.66e-2)" "unprognostic (7.44e-2)" "unprognostic (2.75e-2)" "unprognostic (1.32e-1)" "prognostic unfavorable (1.17e-5)" "unprognostic (1.06e-1)" "unprognostic (1.63e-3)" "unprognostic (2.21e-2)" "unprognostic (3.73e-2)" 285.2 196.0 60.1 159.7 58.6 43.5 70.5 64.8 97.1 51.9 90.6 133.2 179.9 36.3 13.5 55.3 67.4 155.4 58.6 54.9 75.5 41.2 169.6 290.8 370.2 124.7 105.4 32.1 37.5 22.1 39.6 204.9 105.0 37.8 91.3 3.9 51.6 44.5 12.9 18.3 195.7 164.7 100.4 950.7 94.8 33.9 106.0 75.7 29.2 31.8 50.7 191.8 24.6 159.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 1.0 0.2 0.0 0.0 0.6 0.2 2.6 0.0 0.0 0.4 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.1 1.0 0.0 0.1 0.1 0.1 0.0 0.0 1.3 0.0 0.0 57.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 10.4 0.0 0.0 1.2 60.1 58.6 64.8 97.1 54.9 75.5 124.7 105.4 105.0 100.4 106.0 159.3 13.4 6.4 5.2 0.3 13.7 8.9 1.1 0.0 2.8 0.6 4.9 24.5 1.6 15.7 3.1 0.0 0.0 5.8 2.3 0.4 0.0 0.0 3.2 0.0 0.1 34.5 0.0 27.2 0.0 0.2 9.5 4.4 0.0 0.1 5.1 0.1 25.4 6.6 1356.5 0.0 0.1 0.1 0.0 2134.6 202.4 3.6 6.2 1040.7 7.2 29.0 23.6 0.4 0.0 0.0 0.0 0.0 1.1 1.2 0.9 0.4 0.0 0.4 0.7 0.6 46.0 2.5 1.8 0.4 0.8 3.3 6.5 9.9 3.5 0.0 0.0 0.7 C2CD2L "KIAA0285, TMEM24" ENSG00000172375 "C2CD2 like" O14523 11 119102198-119118544 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 37.5;Distal enterocytes: 40.6;Proximal enterocytes: 33.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HMC-1: 50.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011044, HPA075369" Approved Supported "Plasma membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "HPA011044: AB_2668414, HPA075369: " "unprognostic (3.43e-2)" "unprognostic (2.81e-2)" "unprognostic (1.03e-3)" "prognostic favorable (4.92e-4)" "unprognostic (3.18e-2)" "unprognostic (1.19e-1)" "unprognostic (2.25e-3)" "unprognostic (3.37e-3)" "unprognostic (5.28e-2)" "unprognostic (2.09e-1)" "unprognostic (3.99e-3)" "unprognostic (8.19e-2)" "prognostic unfavorable (1.75e-4)" "unprognostic (8.02e-2)" "unprognostic (8.32e-3)" "unprognostic (4.10e-2)" "unprognostic (2.60e-1)" 6.6 8.2 26.9 6.5 27.6 13.6 5.8 15.5 28.9 6.4 15.3 11.1 16.1 6.2 4.8 10.8 8.8 5.3 10.2 26.8 19.6 11.6 13.1 10.3 8.1 18.0 18.4 6.0 11.0 5.7 23.9 3.9 18.4 7.1 7.3 14.1 9.6 5.3 15.3 15.3 17.1 5.1 15.2 14.9 8.1 4.3 21.4 8.5 6.7 7.3 5.7 7.0 6.6 23.7 6.1 4.5 6.0 12.5 7.7 3.2 3.9 9.0 7.8 8.7 7.2 7.3 6.3 9.1 23.1 6.3 9.1 13.4 7.6 3.9 3.4 14.3 6.2 35.7 5.9 5.3 10.2 10.5 50.5 3.7 7.9 16.4 6.1 9.8 5.4 13.5 15.1 16.1 8.3 16.2 11.9 24.9 2.2 15.0 11.8 7.4 5.3 10.5 8.7 3.8 18.7 10.5 3.8 20.1 5.9 2.3 35.3 13.9 6.7 8.1 2.8 9.9 16.1 6.8 4.5 3.5 4.9 17.6 9.1 0.5 1.3 2.7 0.2 1.4 0.4 0.1 0.6 0.6 0.5 0.0 0.6 0.3 0.4 0.8 2.0 0.3 0.6 0.5 26.9 27.6 15.5 28.9 26.8 19.6 18.0 18.4 18.4 15.2 21.4 23.7 5.1 6.4 4.2 9.4 3.7 10.7 1.6 2.3 10.2 15.6 6.8 5.0 2.4 2.8 4.3 1.8 37.5 0.9 7.4 40.6 3.9 3.4 5.4 12.1 2.6 5.7 1.2 7.0 15.1 2.8 1.7 2.5 3.6 4.6 2.5 2.2 11.4 5.4 9.4 21.9 15.0 8.0 0.0 13.9 16.1 1.3 2.1 11.4 7.2 5.6 15.3 5.9 7.2 4.5 8.4 5.1 10.4 1.5 7.2 3.2 33.0 4.0 21.9 29.9 6.6 2.1 3.6 3.7 2.0 10.3 10.9 1.1 8.6 3.6 5.5 1.9 C5orf46 "MGC23985, SSSP1" ENSG00000178776 "Chromosome 5 open reading frame 46" Q6UWT4 5 147880726-147906538 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "salivary gland: 181.8;skin 1: 113.1" "Group enriched" "Detected in some" 12 "Early spermatids: 320.9;Late spermatids: 189.9" "Cancer enhanced" "Detected in many" "renal cancer: 8.3" "Region enriched" "Detected in single" 10 "cerebellum: 2.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 54.2;PC-3: 90.8;SiHa: 20.2;U-2 OS: 58.2;U-251 MG: 23.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA058999, HPA079692" Supported Approved "Nuclear speckles,Mitochondria" "Secreted in other tissues" NA NA 54000 "Cluster 31: Skin - Epidermis development" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" "Nuclear speckles" Mitochondria "HPA058999: , HPA079692: " "unprognostic (1.72e-1)" "prognostic unfavorable (3.98e-4)" "unprognostic (1.26e-4)" "unprognostic (9.75e-3)" "unprognostic (2.95e-3)" "unprognostic (1.69e-3)" "unprognostic (1.99e-2)" "unprognostic (3.08e-2)" "unprognostic (2.22e-1)" "unprognostic (4.96e-2)" "unprognostic (2.86e-3)" "unprognostic (1.10e-1)" "prognostic unfavorable (1.75e-9)" "unprognostic (6.48e-3)" "unprognostic (3.47e-2)" "unprognostic (6.01e-2)" "unprognostic (2.79e-2)" 0.4 0.0 0.0 0.0 0.0 0.0 13.5 2.3 0.1 1.6 0.7 0.4 0.0 0.1 0.4 0.4 0.0 0.2 9.0 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 2.2 0.2 0.9 0.0 0.6 181.8 0.1 0.8 113.1 0.0 3.2 0.0 0.0 0.0 19.2 0.0 0.3 0.2 0.1 0.3 0.0 3.6 0.0 0.7 0.0 0.0 0.0 0.4 0.0 0.0 2.4 1.4 0.0 0.0 0.4 0.0 0.0 0.1 0.0 1.0 0.3 0.0 0.6 0.0 0.2 0.2 0.0 4.6 0.2 0.0 0.0 0.0 0.0 1.1 0.0 8.9 54.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 90.8 0.0 0.5 0.0 0.0 0.1 0.0 0.0 20.2 0.3 0.3 11.1 0.0 0.0 0.0 10.0 58.2 0.8 23.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.8 0.0 0.0 9.2 3.7 11.0 15.7 0.2 1.8 0.0 0.5 0.2 0.0 0.0 15.9 320.9 0.7 0.4 0.3 0.0 0.0 0.0 3.3 0.6 0.2 0.0 3.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 189.9 1.8 0.2 3.6 0.0 0.6 7.7 0.0 0.0 0.0 4.2 0.0 0.4 0.0 1.3 0.0 0.0 0.0 0.3 0.0 0.0 2.1 1.1 0.8 0.0 20.6 1.4 0.1 0.0 0.0 0.2 C6orf15 STG ENSG00000204542 "Chromosome 6 open reading frame 15" Q6UXA7 6 31111223-31112575 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "cervix: 5.5;lymphoid tissue: 3.5;skin 1: 6.7" "Cell type enriched" "Detected in some" 14 "Breast glandular cells: 73.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "RH-30: 13.4;U-2 OS: 5.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA001436 Uncertain "Secreted to extracellular matrix" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 30: Mammary glandular cells - Lactation" "HPA001436: AB_2243752" "unprognostic (2.73e-2)" "unprognostic (5.39e-2)" "unprognostic (1.46e-2)" "unprognostic (3.19e-2)" "unprognostic (1.30e-1)" "unprognostic (2.56e-1)" "unprognostic (1.77e-1)" "unprognostic (3.35e-1)" "unprognostic (3.42e-2)" "unprognostic (1.71e-2)" "unprognostic (1.72e-1)" "unprognostic (1.90e-1)" "unprognostic (1.34e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 3.5 0.0 0.6 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 13.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 73.3 2.8 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 2.3 0.0 1.3 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 C8orf74 ENSG00000171060 "Chromosome 8 open reading frame 74" Q6P047 8 10672628-10700590 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 171 "testis: 17.0" "Group enriched" "Detected in some" 90 "Early spermatids: 186.5;Late spermatids: 392.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA027986 Uncertain Uncertain Nucleoplasm NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 34: Spermatids - Unknown function" Nucleoplasm "HPA027986: AB_10600762" "unprognostic (4.24e-2)" "unprognostic (5.62e-2)" "unprognostic (4.68e-2)" "unprognostic (5.54e-2)" "unprognostic (2.37e-2)" "unprognostic (1.56e-4)" "unprognostic (6.82e-2)" "unprognostic (2.20e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 186.5 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 392.8 1.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CA2 "CA-II, CAII, Car2" ENSG00000104267 "Carbonic anhydrase 2" P00918 8 85463968-85481493 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Lyase "Disease variant, FDA approved drug targets, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 687.4;stomach 1: 1108.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 1773.2;Erythroid cells: 2448.1;Gastric mucus-secreting cells: 1380.7;Muller glia cells: 1536.4;Paneth cells: 781.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 51.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HaCaT: 263.8;HEK 293: 1097.8;THP-1: 461.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001550, CAB010102" Enhanced NA Yes 570000000 "Cluster 38: Basophils - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 6: Erythroid cells - Oxygen transport" "CAB010102: AB_626796, HPA001550: AB_1078393" "unprognostic (6.78e-2)" "unprognostic (3.06e-2)" "unprognostic (1.05e-2)" "unprognostic (1.63e-1)" "unprognostic (2.59e-1)" "unprognostic (9.24e-2)" "unprognostic (1.74e-1)" "unprognostic (1.72e-2)" "unprognostic (1.07e-1)" "unprognostic (5.23e-2)" "unprognostic (1.57e-1)" "unprognostic (9.89e-2)" "prognostic favorable (5.57e-6)" "unprognostic (2.45e-1)" "unprognostic (2.03e-1)" "unprognostic (1.32e-1)" "unprognostic (6.49e-3)" 7.4 10.1 95.9 36.8 127.5 246.8 37.9 122.1 143.8 5.0 444.0 687.4 285.2 2.9 10.6 19.8 2.7 112.7 15.9 105.2 107.8 331.2 273.5 43.1 6.6 115.5 112.0 0.4 55.1 10.1 6.1 19.6 114.2 1.9 643.6 390.4 74.7 68.4 42.7 81.0 31.3 32.3 98.2 8.4 1108.7 21.2 115.6 5.1 15.9 62.8 4.3 2.9 5.2 145.5 3.7 2.8 12.2 0.0 0.1 0.0 31.2 0.0 0.0 0.0 0.0 15.1 0.9 0.0 9.5 0.0 0.1 263.8 37.4 13.2 0.0 0.0 1097.8 35.8 17.0 0.5 0.0 23.7 5.1 0.0 63.9 0.0 3.7 0.0 0.0 0.0 0.3 0.2 0.0 0.4 0.4 41.4 3.7 86.5 0.0 21.2 1.3 0.5 3.7 8.8 0.2 0.3 5.0 0.0 0.1 9.6 0.0 461.5 0.0 0.0 6.6 0.0 0.4 0.4 1.0 0.1 1.8 0.1 0.0 51.2 5.3 8.6 0.2 15.0 7.4 1.3 0.1 0.8 15.4 3.0 0.0 0.0 12.6 0.1 13.4 1.4 0.0 33.3 95.9 127.5 122.1 143.8 105.2 107.8 115.5 112.0 114.2 98.2 115.6 145.5 19.4 16.0 79.9 34.0 19.6 90.6 1.3 152.5 17.6 23.1 56.9 18.4 19.8 430.4 22.4 161.8 64.6 15.2 2.4 1773.2 348.3 60.1 65.9 3.3 1.3 26.7 30.5 2448.1 1.4 11.3 403.1 6.4 1380.7 8.3 15.9 0.4 4.2 135.6 35.4 13.5 22.3 116.0 10.2 11.0 216.5 232.1 3.4 51.8 74.7 6.5 6.6 1536.4 1.0 3.0 226.4 16.1 781.9 2.2 10.3 3.5 0.3 468.2 3.9 66.1 0.0 12.1 8.2 3.1 2.8 31.2 111.7 17.1 11.7 0.7 390.8 0.5 CADM3 "BIgR, FLJ10698, IGSF4B, Necl-1, NECL1, SynCAM3, TSLL1" ENSG00000162706 "Cell adhesion molecule 3" Q8N126 1 159171609-159203313 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 151.6;placenta: 80.6" "Cell type enhanced" "Detected in some" "Bipolar cells: 146.4;Excitatory neurons: 35.5;Fibroblasts: 39.5;Horizontal cells: 35.3;Inhibitory neurons: 40.5;Muller glia cells: 39.4" "Cancer enriched" "Detected in many" 4 "glioma: 27.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HHSteC: 65.0;HSkMC: 218.8;hTERT-HME1: 118.5;WM-115: 60.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002981, CAB025746" Enhanced Supported "Intracellular and membrane" NA NA 800000 "Cluster 6: Brain - Smell perception" "Cluster 30: Epithelial cell lines - Translation" "Cluster 33: Fibroblasts - ECM organization" "CAB025746: , HPA002981: AB_1078916" "unprognostic (1.74e-2)" "unprognostic (8.26e-2)" "unprognostic (1.34e-2)" "unprognostic (1.33e-2)" "unprognostic (9.32e-2)" "unprognostic (4.84e-2)" "unprognostic (1.05e-1)" "unprognostic (2.06e-1)" "unprognostic (2.74e-1)" "unprognostic (1.12e-1)" "unprognostic (1.98e-2)" "unprognostic (6.12e-3)" "prognostic unfavorable (1.03e-5)" "unprognostic (5.52e-2)" "unprognostic (2.59e-1)" "unprognostic (3.64e-1)" "prognostic unfavorable (5.75e-4)" 17.3 7.9 102.0 15.1 139.6 0.1 9.2 151.6 145.4 27.6 1.2 28.2 4.4 3.9 1.3 11.5 9.2 6.2 18.1 143.1 96.2 2.2 0.6 5.0 14.3 87.4 84.1 1.5 2.2 0.2 31.0 80.6 120.7 5.1 14.4 66.8 5.9 4.7 2.3 13.0 15.8 6.1 66.3 13.3 11.1 3.0 99.4 1.2 7.3 6.5 9.8 16.2 31.0 60.8 0.0 0.0 0.6 0.0 4.2 1.2 0.0 0.0 0.0 9.4 1.8 0.0 0.0 0.1 0.5 0.0 0.1 0.1 0.0 0.0 3.8 0.0 0.0 3.7 0.0 0.0 65.0 0.0 0.2 218.8 0.0 0.1 118.5 0.0 5.3 0.0 0.0 0.2 2.1 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.9 0.1 4.1 0.0 0.0 5.0 0.0 0.1 9.1 0.0 32.2 0.0 0.1 0.0 0.0 0.0 0.3 0.0 60.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 102.0 139.6 151.6 145.4 143.1 96.2 87.4 84.1 120.7 66.3 99.4 60.8 4.2 0.0 0.5 11.4 0.0 6.6 0.1 0.0 0.6 146.4 0.1 0.8 0.6 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 8.0 0.0 0.2 8.0 0.0 0.0 35.5 0.0 0.8 39.5 0.5 0.0 0.0 0.0 3.6 0.0 1.2 35.3 40.5 0.0 0.0 0.0 10.7 8.3 0.6 0.3 24.9 1.9 0.0 39.4 0.0 18.6 2.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 9.6 0.0 16.3 3.6 3.1 2.6 0.3 4.3 0.7 0.6 0.0 0.0 0.1 CAMK2B "CAM2, CAMK2, CAMKB, CaMKIIβ" ENSG00000058404 "Calcium/calmodulin dependent protein kinase II beta" Q13554 7 44217150-44334577 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Actin-binding, Calmodulin-binding, Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 248.8;skeletal muscle: 132.5" "Cell type enriched" "Detected in many" 7 "Bipolar cells: 857.4" "Cancer enhanced" "Detected in many" "glioma: 6.0;thyroid cancer: 6.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 7 "SCLC-21H: 75.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006849, HPA026307, HPA051783, HPA051785, HPA053973" Enhanced Supported Supported "Plasma membrane,Cell Junctions,Cytosol" NA NA 600000 "Cluster 11: Basophils - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane" "Cell Junctions, Cytosol" "CAB006849: , HPA026307: AB_1845941, HPA051783: AB_2681608, HPA051785: AB_2681609, HPA053973: AB_2682328" "unprognostic (1.88e-3)" "unprognostic (4.49e-2)" "unprognostic (3.55e-3)" "unprognostic (1.36e-2)" "unprognostic (5.25e-2)" "unprognostic (2.90e-2)" "unprognostic (8.78e-2)" "unprognostic (1.09e-1)" "unprognostic (1.44e-1)" "unprognostic (2.71e-1)" "unprognostic (1.17e-2)" "unprognostic (1.60e-2)" "unprognostic (5.23e-7)" "unprognostic (7.04e-2)" "unprognostic (2.34e-1)" "unprognostic (3.15e-2)" "unprognostic (3.95e-2)" 0.5 11.3 77.9 0.6 109.0 0.1 1.4 113.0 248.8 0.1 0.0 1.0 1.0 0.2 28.3 1.4 1.1 0.2 65.4 197.6 12.6 1.6 7.7 0.3 1.3 4.4 11.9 0.3 3.8 6.1 51.3 0.1 4.6 3.2 0.4 21.4 1.4 1.6 132.5 1.2 0.9 0.1 3.2 0.3 2.3 2.1 25.9 0.8 20.3 59.2 1.6 0.0 0.3 80.4 0.0 0.8 0.4 0.6 0.0 0.4 0.4 0.3 0.1 0.3 0.0 0.3 0.1 0.2 1.6 0.4 0.1 0.3 0.4 1.4 0.1 2.0 4.5 0.1 0.2 0.2 0.1 0.0 0.9 0.1 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.8 0.1 10.1 0.0 0.4 0.2 0.1 4.4 0.2 1.7 0.3 0.0 0.0 75.5 4.0 0.4 0.0 0.0 0.1 3.5 0.3 0.4 0.5 0.7 0.4 0.1 0.9 0.8 0.2 0.2 0.0 0.5 1.0 0.1 0.2 0.1 0.2 0.2 0.2 0.2 0.1 0.1 0.3 0.2 0.2 0.4 0.7 0.3 0.2 0.2 0.2 77.9 109.0 113.0 248.8 197.6 12.6 4.4 11.9 4.6 3.2 25.9 80.4 0.1 0.0 0.0 67.3 0.2 1.1 21.5 0.0 10.8 857.4 3.1 17.5 88.9 2.8 0.0 0.0 45.9 0.1 0.0 0.5 9.8 0.0 0.9 2.3 0.4 1.6 40.7 0.0 111.4 0.0 0.2 2.9 4.1 5.6 4.5 15.4 0.0 4.3 0.2 60.6 90.9 1.5 2.0 0.6 0.4 2.9 1.8 0.5 1.8 5.6 0.0 23.2 0.0 19.6 5.4 0.1 1.2 0.0 0.1 3.3 0.1 1.9 0.0 53.1 0.0 6.9 1.7 0.2 7.8 0.9 0.4 0.3 0.2 0.2 0.3 6.6 CAPG "AFCP, MCP" ENSG00000042493 "Capping actin protein, gelsolin like" P40121 2 85394753-85418432 "Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 548.8;Hofbauer cells: 1107.4;Macrophages: 432.1;monocytes: 432.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 1136.5;classical monocyte: 1139.3;eosinophil: 712.7;intermediate monocyte: 431.6;memory B-cell: 575.6;myeloid DC: 1363.2;naive B-cell: 516.8;NK-cell: 605.5;plasmacytoid DC: 959.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 563.6;HMC-1: 972.7;SK-MEL-30: 722.2;THP-1: 513.5;U-937: 569.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018843, HPA019080, HPA019092" Enhanced Enhanced Nucleoplasm Yes No 5400000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm "HPA018843: AB_2669948, HPA019080: AB_1845979, HPA019092: AB_1845980" "unprognostic (2.82e-2)" "unprognostic (1.37e-1)" "unprognostic (8.80e-2)" "unprognostic (1.28e-2)" "unprognostic (4.37e-2)" "unprognostic (7.52e-2)" "prognostic unfavorable (3.22e-5)" "unprognostic (8.83e-2)" "unprognostic (3.22e-2)" "unprognostic (1.54e-1)" "unprognostic (5.70e-3)" "unprognostic (1.75e-1)" "prognostic favorable (2.96e-4)" "unprognostic (1.45e-1)" "unprognostic (7.68e-2)" "unprognostic (5.30e-3)" "unprognostic (7.89e-3)" 92.4 26.3 42.8 82.4 44.2 159.3 94.9 46.3 79.6 119.1 37.5 56.9 30.3 50.0 46.2 289.5 48.7 44.4 19.2 41.7 51.1 201.1 8.9 175.7 117.9 60.2 46.3 19.7 44.9 151.7 27.2 26.1 57.2 76.5 42.9 4.2 111.8 38.0 16.5 219.9 54.2 24.5 57.5 46.2 94.4 26.0 66.1 58.0 162.3 5.8 109.5 97.1 174.8 79.4 165.5 75.9 0.7 6.9 50.2 102.8 83.7 59.6 6.1 51.2 49.8 9.4 563.6 28.1 96.6 116.0 64.0 181.1 0.2 113.7 23.0 142.0 4.4 74.3 128.0 29.3 40.6 44.8 972.7 93.8 80.5 53.8 70.3 3.6 37.5 143.8 8.2 60.1 38.1 150.1 101.3 414.8 23.2 166.5 112.8 87.3 13.3 11.8 220.6 77.7 0.8 1.4 86.9 128.4 722.2 44.2 40.0 513.5 148.7 111.6 26.8 4.6 2.4 1.4 6.2 10.3 259.5 569.5 1.5 1136.5 1139.3 712.7 12.2 431.6 39.2 575.6 107.8 41.1 1363.2 516.8 30.5 13.9 162.9 605.5 131.3 959.7 122.1 977.9 42.8 44.2 46.3 79.6 41.7 51.1 60.2 46.3 57.2 57.5 66.1 79.4 6.6 19.2 24.5 3.3 84.7 121.2 167.5 265.0 60.9 0.8 86.8 70.4 1.3 51.5 119.6 316.3 0.0 34.3 91.5 211.0 211.3 113.8 4.1 33.0 10.3 16.2 28.8 16.0 0.2 91.5 324.0 34.7 124.9 63.9 548.8 1.2 3.6 1.1 1107.4 1.7 0.2 55.9 50.8 141.6 337.2 15.2 46.9 432.1 147.7 1.0 432.4 43.6 11.3 0.5 0.1 405.8 205.4 22.6 17.2 106.0 74.1 168.5 48.8 1.7 13.1 2.0 54.0 9.6 33.1 167.4 169.5 35.7 101.9 0.9 83.9 253.1 CAPN1 "CANP, CANPL1, muCANP, muCL" ENSG00000014216 "Calpain 1" P07384 11 65180566-65212006 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 276.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RT4: 516.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005992 Enhanced Supported Cytosol NA NA 9100000 "Cluster 46: Basophils - DNA binding" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA005992: AB_1845924" "unprognostic (2.07e-1)" "unprognostic (2.15e-1)" "unprognostic (2.69e-1)" "unprognostic (1.40e-1)" "unprognostic (4.06e-2)" "unprognostic (1.10e-1)" "unprognostic (1.91e-2)" "unprognostic (2.48e-2)" "unprognostic (7.23e-2)" "unprognostic (2.23e-2)" "prognostic unfavorable (4.30e-4)" "unprognostic (3.33e-1)" "prognostic favorable (7.06e-8)" "unprognostic (5.70e-3)" "unprognostic (1.51e-1)" "unprognostic (1.86e-1)" "unprognostic (2.98e-1)" 44.8 43.1 27.8 51.9 26.1 66.5 48.4 29.7 30.1 80.9 28.3 78.6 80.4 56.3 27.5 276.2 92.3 55.5 53.1 27.7 33.0 53.1 44.3 56.9 57.0 41.4 31.5 44.5 71.7 36.6 40.8 56.2 43.4 62.1 57.6 9.6 118.7 67.4 84.8 125.1 88.1 45.3 33.9 50.2 65.5 6.1 37.9 49.5 71.5 55.3 86.4 83.4 117.4 27.4 285.6 147.9 42.9 97.2 77.9 104.3 127.0 84.1 144.2 103.0 74.9 94.8 250.2 71.2 136.0 179.3 111.1 409.8 60.9 366.9 32.2 76.4 44.1 170.8 80.4 93.7 76.2 40.6 228.0 107.3 196.8 85.9 43.2 92.6 178.5 50.6 103.1 55.9 87.4 181.8 83.1 130.6 120.5 145.2 133.8 80.7 43.0 43.2 138.1 516.5 76.2 55.7 87.4 331.4 80.3 45.8 142.8 77.9 147.1 73.1 50.5 159.0 38.5 33.8 26.9 86.6 127.5 48.8 82.3 87.6 57.5 77.9 39.4 51.2 31.0 30.8 30.7 35.8 48.4 31.7 17.6 24.9 33.1 34.8 30.4 38.1 35.9 74.8 27.8 26.1 29.7 30.1 27.7 33.0 41.4 31.5 43.4 33.9 37.9 27.4 27.3 25.6 27.9 21.5 39.6 59.9 127.3 120.5 56.9 10.7 44.7 36.6 22.0 74.4 81.0 77.3 20.9 238.5 61.4 184.2 39.2 180.5 0.5 41.9 26.3 31.3 44.3 58.3 15.9 115.8 111.7 39.6 57.6 58.2 46.9 48.6 37.9 36.7 88.7 21.9 15.2 76.9 59.0 51.2 34.0 2.0 43.5 67.1 48.0 14.0 112.7 38.5 61.8 6.6 1.9 179.4 124.1 50.8 17.7 78.6 155.6 34.6 71.1 16.2 39.5 25.3 36.7 0.5 2.8 102.0 68.9 196.6 40.2 35.4 125.3 156.6 CAPN13 FLJ23523 ENSG00000162949 "Calpain 13" Q6MZZ7 2 30722771-30820542 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 29.2;stomach 1: 28.5" "Cell type enhanced" "Detected in many" "Club cells: 76.6;Gastric mucus-secreting cells: 50.0;Proximal enterocytes: 35.2;Undifferentiated cells: 18.1;Urothelial cells: 19.4" "Cancer enhanced" "Detected in many" "endometrial cancer: 11.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "RT4: 9.3;SK-BR-3: 21.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA029496, HPA029497, HPA030034" Uncertain Approved Nucleoplasm NA NA "Cluster 9: Intestine - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm "HPA029496: AB_2673072, HPA029497: AB_2673073, HPA030034: AB_2673281" "unprognostic (7.42e-2)" "unprognostic (1.19e-1)" "unprognostic (7.01e-3)" "unprognostic (1.96e-1)" "unprognostic (8.56e-2)" "unprognostic (1.51e-1)" "unprognostic (1.68e-1)" "unprognostic (1.32e-3)" "unprognostic (2.17e-1)" "unprognostic (2.66e-2)" "unprognostic (1.11e-1)" "unprognostic (2.49e-1)" "unprognostic (1.96e-2)" "unprognostic (3.64e-1)" "unprognostic (3.32e-2)" "unprognostic (5.03e-2)" "unprognostic (4.28e-3)" 0.0 0.0 0.8 0.0 1.4 0.0 7.2 0.9 1.3 9.7 1.0 11.4 20.8 0.2 0.3 0.9 1.1 2.8 0.0 0.7 0.8 2.5 0.2 7.2 0.0 1.1 1.3 0.0 3.6 0.4 0.2 0.0 1.0 3.8 24.6 0.0 1.2 0.1 0.0 0.2 29.2 0.2 1.0 0.1 28.5 0.1 1.1 0.0 0.0 0.0 0.6 4.1 0.5 2.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.6 9.3 0.1 0.4 0.0 21.9 0.0 0.7 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.4 0.9 1.3 0.7 0.8 1.1 1.3 1.0 1.0 1.1 2.3 0.0 6.4 3.1 0.3 0.0 0.0 10.2 3.5 4.0 0.0 4.2 1.8 1.3 0.0 76.6 1.8 0.0 0.0 0.0 16.9 0.0 1.3 0.8 2.0 0.0 0.1 15.0 0.0 0.3 5.3 0.0 0.6 50.0 0.7 1.3 0.0 0.0 0.0 0.0 0.0 1.5 12.0 6.1 0.0 0.0 0.4 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 8.4 1.9 6.2 0.0 0.0 2.7 35.2 0.2 12.4 0.0 0.0 0.0 6.1 0.0 0.1 1.4 0.0 0.0 0.1 0.0 18.1 19.4 CAPN15 SOLH ENSG00000103326 "Calpain 15" O75808 16 527712-554636 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 54.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "basophil: 4.7;neutrophil: 16.2" "Lineage enriched" "Detected in many" 7 "granulocytes: 16.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011960 Uncertain Approved Nucleoplasm NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA011960: AB_10610556" "unprognostic (4.11e-2)" "unprognostic (1.63e-1)" "unprognostic (1.14e-1)" "unprognostic (2.66e-1)" "unprognostic (7.18e-2)" "unprognostic (1.12e-2)" "unprognostic (1.54e-3)" "unprognostic (8.31e-3)" "unprognostic (1.32e-1)" "unprognostic (1.24e-1)" "unprognostic (1.86e-1)" "unprognostic (4.02e-2)" "unprognostic (2.53e-3)" "unprognostic (2.54e-3)" "unprognostic (5.91e-2)" "unprognostic (1.83e-1)" "unprognostic (9.23e-3)" 13.0 12.0 3.6 7.2 2.5 8.1 10.8 11.6 6.2 12.2 0.2 20.2 16.3 13.4 0.4 18.5 13.2 1.6 11.2 3.2 0.2 18.4 17.2 15.3 5.1 4.1 1.0 13.2 24.8 2.2 15.2 2.6 1.4 12.3 2.3 1.1 12.6 2.8 14.9 22.3 22.7 1.2 0.2 21.2 16.5 18.7 2.1 2.8 11.7 0.9 2.5 12.5 12.8 0.8 16.8 21.5 3.0 9.3 1.7 3.4 46.2 17.5 4.6 4.9 3.3 28.2 12.1 24.0 16.3 3.2 5.0 21.9 2.0 6.9 1.8 25.2 37.1 20.2 25.7 17.6 7.3 23.8 27.3 3.9 4.0 4.9 2.2 2.9 5.3 14.7 37.6 7.1 1.6 25.9 27.1 26.0 26.7 8.6 20.2 46.5 8.7 24.2 3.3 11.0 19.6 17.8 11.7 16.2 10.2 1.8 13.3 24.7 26.2 15.3 21.4 15.7 22.0 18.2 11.0 21.3 6.7 13.8 9.7 4.7 1.3 0.8 0.3 0.8 0.1 0.4 0.1 0.4 0.3 2.3 0.1 0.2 16.2 1.1 1.3 0.5 0.2 0.3 3.6 2.5 11.6 6.2 3.2 0.2 4.1 1.0 1.4 0.2 2.1 0.8 7.6 3.2 8.4 10.1 5.9 8.9 5.7 6.2 3.4 12.1 7.6 6.6 3.1 8.6 5.6 7.3 16.7 3.7 22.3 54.3 1.9 6.2 16.5 6.1 8.9 8.7 4.2 1.7 10.6 15.7 4.4 6.9 20.4 13.3 7.0 10.8 8.9 16.5 6.8 20.2 11.3 26.9 8.2 12.0 6.8 6.2 7.5 8.2 1.8 7.5 6.5 9.1 23.7 10.6 7.8 14.3 37.1 4.5 5.8 13.4 33.1 5.7 4.6 11.2 0.0 10.2 5.2 5.3 7.4 5.8 8.0 2.5 9.2 9.6 25.9 11.6 CAPZA1 ENSG00000116489 "Capping actin protein of muscle Z-line subunit alpha 1" P52907 1 112619805-112671616 "Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" CAB045963 Approved NA NA 16000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 32: U-937 - Innate immune response" "Cluster 24: Non-specific - Transcription regulation" "CAB045963: AB_11126023" "unprognostic (7.06e-2)" "unprognostic (1.97e-1)" "unprognostic (1.90e-3)" "unprognostic (1.88e-2)" "unprognostic (1.20e-1)" "unprognostic (1.23e-1)" "prognostic unfavorable (2.54e-6)" "unprognostic (1.17e-3)" "unprognostic (3.15e-2)" "unprognostic (3.82e-3)" "unprognostic (4.59e-3)" "unprognostic (9.50e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (4.36e-3)" "unprognostic (1.72e-1)" "unprognostic (2.42e-1)" "unprognostic (2.82e-1)" 73.7 49.1 42.5 115.3 43.6 156.4 55.7 46.4 51.7 48.3 45.7 86.1 67.9 43.1 61.5 96.3 42.9 59.1 27.9 40.5 49.7 41.1 73.1 65.4 154.0 51.6 49.3 30.6 35.5 39.6 21.4 85.4 51.2 42.4 95.0 37.2 38.5 37.4 25.4 92.4 70.8 63.9 49.1 105.2 70.9 71.1 50.6 118.2 48.1 22.1 187.7 97.3 52.8 57.5 308.0 88.9 148.4 120.7 180.6 207.9 186.5 237.7 245.3 236.7 210.9 120.7 126.9 319.6 174.8 277.6 108.0 142.6 199.9 251.3 293.4 245.5 100.2 279.0 141.8 148.7 212.8 507.3 376.5 224.6 186.5 230.7 219.2 140.5 268.1 143.2 287.3 191.6 335.6 177.2 262.8 222.6 146.3 179.7 180.3 192.5 292.0 158.8 207.9 221.3 102.2 109.6 274.3 246.9 192.6 118.2 127.8 441.6 305.8 192.8 191.6 317.7 292.2 135.0 134.2 359.8 331.4 381.5 450.4 396.9 254.5 319.7 172.1 385.9 194.5 198.3 188.8 209.1 207.9 145.0 105.4 171.0 524.7 145.9 434.0 164.6 252.5 369.9 42.5 43.6 46.4 51.7 40.5 49.7 51.6 49.3 51.2 49.1 50.6 57.5 59.5 28.9 49.0 59.4 186.0 180.9 73.7 87.4 63.2 31.2 73.3 35.3 22.0 54.3 69.0 101.2 25.0 138.8 194.9 152.4 92.0 94.9 380.4 62.1 95.4 78.0 61.1 104.5 48.3 111.9 206.8 72.1 59.1 86.0 92.0 48.8 83.2 74.5 233.1 43.7 47.8 101.5 52.9 320.0 361.0 210.2 57.2 211.9 122.7 54.4 236.5 33.5 125.7 55.8 73.7 168.9 135.7 55.3 137.2 105.7 89.0 88.8 71.4 31.2 65.7 42.8 79.6 166.3 67.7 110.2 237.8 184.0 196.7 73.9 110.3 147.0 CARD14 "BIMP2, CARMA2, PSORS2" ENSG00000141527 "Caspase recruitment domain family member 14" Q9BXL6 17 80169992-80209331 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Apoptosis "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 13.5;skin 1: 14.4;vagina: 7.3" "Cell type enhanced" "Detected in many" "Kupffer cells: 8.2;Microglial cells: 6.5;Oligodendrocytes: 11.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MCF7: 5.2;SK-BR-3: 6.9;T-47d: 10.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA023388 Supported Aggresome,Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 6: T47d - Mammary gland" "Cluster 35: Glandular cells - Unknown function" Cytosol Aggresome "HPA023388: AB_1846020" "unprognostic (9.79e-3)" "unprognostic (3.86e-2)" "unprognostic (4.26e-1)" "unprognostic (1.05e-5)" "unprognostic (2.65e-2)" "unprognostic (1.37e-2)" "unprognostic (2.92e-4)" "unprognostic (1.92e-1)" "unprognostic (1.47e-1)" "unprognostic (2.63e-1)" "unprognostic (3.01e-1)" "unprognostic (5.48e-2)" "unprognostic (1.62e-8)" "unprognostic (2.52e-1)" "unprognostic (2.06e-1)" "unprognostic (2.38e-1)" "unprognostic (2.34e-1)" 0.3 1.1 0.3 0.6 0.3 0.2 2.6 0.1 0.4 4.9 0.1 0.4 1.1 0.3 0.3 13.5 0.6 0.4 0.2 0.3 0.3 0.6 0.3 0.6 0.6 0.5 0.3 0.4 0.4 0.0 0.5 0.2 0.4 2.5 0.0 0.3 3.3 0.0 0.4 14.4 0.8 0.0 0.1 1.5 0.5 1.2 0.4 0.0 0.5 0.0 1.6 1.0 7.3 0.4 1.7 0.4 0.3 0.2 0.0 0.0 1.9 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.3 0.0 0.3 0.3 0.0 0.0 0.0 0.8 0.6 0.0 1.9 0.2 0.0 0.3 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.3 0.9 0.0 5.2 0.0 0.0 0.1 1.0 0.1 0.0 1.1 0.4 0.0 1.6 0.4 0.1 0.0 6.9 0.8 0.4 10.4 0.0 0.4 0.1 0.3 0.3 0.0 2.2 0.1 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.1 0.4 0.3 0.3 0.5 0.3 0.4 0.1 0.4 0.4 0.3 0.0 1.1 1.6 0.1 1.8 4.0 2.1 0.0 0.6 4.5 2.2 0.9 2.8 2.0 0.0 0.0 0.2 0.2 0.1 0.0 0.6 0.7 1.3 0.2 0.9 0.0 0.0 0.9 2.2 0.4 0.5 0.0 1.5 0.0 0.4 0.7 0.0 0.8 0.0 0.8 0.1 0.0 8.2 0.8 0.1 0.3 0.6 1.8 6.5 0.1 1.4 0.0 1.0 11.6 1.8 0.1 0.4 0.1 3.2 0.9 0.3 3.6 0.8 0.0 0.2 0.3 1.3 0.4 5.0 3.0 1.5 0.3 0.7 0.5 3.6 CARD9 ENSG00000187796 "Caspase recruitment domain family member 9" Q9H257 9 136361903-136373681 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Adaptive immunity, Immunity, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 13.0;lymphoid tissue: 9.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 14.1;Hofbauer cells: 21.2;Horizontal cells: 15.2;Kupffer cells: 18.8;Langerhans cells: 12.9;Macrophages: 22.3;monocytes: 16.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 57.6;non-classical monocyte: 50.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HEL: 22.5;HMC-1: 69.7;NB-4: 50.0;THP-1: 63.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA059502 Enhanced NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA059502: AB_2684042" "unprognostic (7.03e-2)" "unprognostic (5.61e-2)" "unprognostic (8.62e-3)" "unprognostic (2.06e-2)" "unprognostic (2.75e-1)" "unprognostic (2.11e-2)" "unprognostic (3.89e-3)" "unprognostic (6.36e-2)" "unprognostic (2.64e-1)" "unprognostic (1.55e-2)" "unprognostic (7.68e-3)" "unprognostic (6.97e-2)" "unprognostic (2.02e-6)" "unprognostic (2.52e-1)" "unprognostic (4.87e-3)" "unprognostic (3.06e-1)" "unprognostic (1.06e-1)" 1.2 1.3 0.5 4.7 0.5 13.0 1.2 2.5 1.0 2.0 0.3 1.0 1.3 0.8 0.4 1.0 1.8 1.0 0.5 0.5 0.7 1.0 0.9 3.4 1.2 1.9 0.9 0.3 0.5 0.1 0.8 0.9 1.3 1.8 0.4 0.2 1.1 1.0 0.2 2.7 1.8 1.1 1.4 9.9 0.6 0.4 1.1 0.4 0.4 0.0 1.5 1.2 1.1 1.7 0.1 0.0 0.3 0.0 0.0 0.0 4.6 9.5 0.3 0.2 0.0 0.7 0.0 0.0 0.1 3.5 0.0 0.0 0.3 0.0 0.1 0.0 0.2 22.5 0.1 6.8 4.9 12.2 69.7 0.0 0.1 0.2 0.2 0.0 0.1 0.0 5.3 0.0 0.0 0.2 0.0 50.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 12.3 0.0 16.0 0.1 0.0 4.1 63.7 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.1 16.0 0.0 6.9 34.5 11.5 0.0 57.6 0.9 0.0 0.0 0.0 26.0 0.0 0.0 0.0 2.3 0.7 50.5 0.1 0.5 14.1 0.5 0.5 2.5 1.0 0.5 0.7 1.9 0.9 1.3 1.4 1.1 1.7 0.8 0.0 4.6 4.6 1.1 1.8 0.6 0.3 3.4 0.2 4.2 4.3 2.6 0.0 4.9 3.7 0.0 0.4 2.2 0.4 1.9 0.1 1.0 1.2 14.1 1.1 0.0 2.5 2.1 0.0 0.4 2.1 1.5 1.4 10.8 0.4 0.7 0.1 21.2 15.2 1.1 0.0 0.0 18.8 12.9 6.9 0.3 22.3 1.8 6.5 16.3 4.6 3.1 0.0 0.2 0.0 0.1 0.0 1.4 0.1 0.0 0.3 0.6 0.9 0.0 0.3 1.5 1.0 1.5 0.9 1.7 0.4 1.4 0.2 0.2 0.6 CASQ2 PDIB2 ENSG00000118729 "Calsequestrin 2" O14958 1 115700021-115768714 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Muscle protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "heart muscle: 1056.7" "Cell type enriched" "Detected in some" 8 "Cardiomyocytes: 777.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 5.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 19 "HSkMC: 13.6" "Region enriched" "Detected in all" 6 "cerebellum: 43.1" "Low region specificity" "Detected in all" "HPA027285, HPA055298" Enhanced "Intracellular and membrane" NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA027285: AB_1845933, HPA055298: AB_2682777" "unprognostic (1.13e-1)" "unprognostic (1.52e-1)" "unprognostic (9.70e-3)" "unprognostic (1.28e-1)" "unprognostic (3.41e-2)" "prognostic unfavorable (2.30e-4)" "unprognostic (1.03e-4)" "unprognostic (1.78e-1)" "unprognostic (2.37e-1)" "unprognostic (1.92e-1)" "unprognostic (1.34e-1)" "unprognostic (8.92e-2)" "unprognostic (7.20e-3)" "unprognostic (1.82e-2)" "unprognostic (1.80e-1)" "unprognostic (2.83e-1)" "prognostic unfavorable (2.25e-5)" 31.9 3.0 3.5 6.4 2.3 0.0 8.9 2.8 4.0 8.0 2.0 59.8 3.3 17.2 6.5 38.5 14.7 6.6 1056.7 1.8 3.6 3.5 0.6 5.3 0.8 1.9 4.8 5.3 1.2 1.6 0.9 1.6 2.1 13.8 17.0 0.3 7.6 20.2 182.1 4.9 9.1 39.1 1.9 0.8 14.2 1.5 6.4 1.6 4.1 165.0 1.3 43.9 6.9 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 2.3 2.8 4.0 1.8 3.6 1.9 4.8 2.1 1.9 6.4 1.9 2.7 0.0 0.0 0.3 0.0 0.6 0.3 0.0 0.6 0.2 0.1 0.4 777.8 0.0 0.0 1.8 0.0 0.4 0.1 0.0 0.0 0.0 15.5 0.3 0.0 4.8 0.0 0.0 0.7 0.0 0.3 17.5 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 20.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 1.0 1.3 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 92.1 11.0 73.4 0.1 0.4 0.2 0.3 0.0 0.1 0.0 0.0 0.0 CBR1 "CBR, SDR21C1" ENSG00000159228 "Carbonyl reductase 1" P16152 21 36069941-36073166 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 583.9" "Cell type enhanced" "Detected in all" "Basal squamous epithelial cells: 524.2;Distal tubular cells: 757.2;Proximal enterocytes: 1270.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA018433, CAB034291" Enhanced Approved Nucleoplasm,Cytosol NA NA 12000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 45: Intestine - Brush border" "Cluster 16: U-266 - Nucleosome" "Cluster 45: Enterocytes - Digestion" Nucleoplasm Cytosol "CAB034291: AB_2070856, HPA018433: AB_1846109" "prognostic favorable (2.18e-4)" "unprognostic (9.78e-2)" "unprognostic (3.25e-2)" "unprognostic (2.14e-1)" "unprognostic (6.47e-3)" "unprognostic (1.69e-1)" "unprognostic (1.19e-1)" "unprognostic (6.37e-2)" "unprognostic (4.56e-2)" "unprognostic (1.28e-1)" "unprognostic (7.20e-2)" "unprognostic (4.00e-1)" "prognostic favorable (4.75e-4)" "unprognostic (2.37e-1)" "unprognostic (2.47e-1)" "unprognostic (6.13e-3)" "unprognostic (2.47e-2)" 32.4 95.3 150.0 25.6 200.0 10.1 29.5 186.1 174.1 52.7 207.0 68.6 583.9 41.3 50.5 189.5 34.6 47.1 29.5 154.6 166.7 125.6 252.8 41.1 28.3 173.1 175.1 28.8 36.1 38.6 35.3 27.6 175.6 48.7 50.9 10.2 101.8 42.2 33.6 111.8 345.9 34.4 166.2 39.9 133.5 18.1 180.3 22.7 46.4 23.3 36.7 51.0 85.3 266.6 114.4 180.4 22.6 55.9 115.0 115.3 1.2 123.6 97.0 72.4 86.4 68.9 67.8 28.2 78.7 128.1 137.3 84.6 46.3 132.3 55.7 133.8 95.3 82.5 105.1 48.1 65.7 49.1 77.5 56.1 165.6 70.7 30.8 83.0 78.4 0.0 0.0 21.3 67.6 121.2 24.7 50.7 0.4 0.0 123.3 0.4 0.4 80.5 195.7 60.9 60.5 52.1 121.3 186.3 157.3 17.6 86.1 69.4 71.1 78.8 30.8 202.9 96.1 131.8 268.9 0.7 144.0 48.6 115.6 7.1 134.0 68.6 64.4 198.5 54.6 67.2 79.7 60.8 109.6 61.2 102.6 75.4 9.2 77.3 156.9 39.6 89.0 162.1 150.0 200.0 186.1 174.1 154.6 166.7 173.1 175.1 175.6 166.2 180.3 266.6 26.4 121.8 69.3 17.9 22.5 128.2 63.1 295.2 524.2 11.6 27.7 98.8 20.9 77.2 117.1 95.6 2.1 116.6 15.7 91.2 757.2 93.7 8.9 31.7 45.5 23.1 38.6 32.0 6.5 70.0 80.4 65.7 127.4 45.1 34.9 30.8 41.7 277.2 85.1 3.3 6.8 94.4 396.7 66.6 27.5 4.3 122.7 49.5 90.7 4.7 79.2 69.8 23.7 16.6 128.2 91.8 146.6 132.4 41.3 66.4 1270.3 326.0 121.2 8.3 26.3 51.3 90.7 5.8 17.4 403.5 123.6 89.2 30.7 55.6 145.8 55.0 CCDC80 "CL2, DRO1, LINC01279, SSG1, TCONS_00006930, URB" ENSG00000091986 "Coiled-coil domain containing 80" Q76M96 3 112596797-112649530 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 450.8;Fibroblasts: 921.6;Late spermatids: 353.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 521.4;fHDF/TERT166: 1281.3;hTERT-RPE1: 2404.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002266 Approved "Secreted to extracellular matrix" NA NA 510000 "Cluster 41: Basophils - Cellular respiration" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA002266: AB_1078423" "unprognostic (1.26e-1)" "unprognostic (1.89e-1)" "unprognostic (1.26e-2)" "unprognostic (3.19e-1)" "unprognostic (2.29e-1)" "unprognostic (1.50e-1)" "unprognostic (2.82e-1)" "unprognostic (2.53e-2)" "unprognostic (2.30e-3)" "unprognostic (1.99e-3)" "unprognostic (8.40e-2)" "unprognostic (6.30e-2)" "prognostic unfavorable (2.86e-5)" "unprognostic (5.97e-3)" "unprognostic (1.65e-1)" "unprognostic (1.55e-1)" "prognostic unfavorable (1.26e-4)" 244.9 15.0 6.4 83.5 6.9 1.1 218.3 9.6 8.6 305.3 24.4 74.5 8.7 276.5 76.8 92.4 82.2 234.0 218.8 6.8 10.2 17.7 6.6 74.0 18.5 12.2 11.4 62.2 28.7 12.4 10.8 26.0 9.3 67.8 73.4 9.4 34.7 78.7 13.4 79.1 25.1 360.3 11.1 34.8 47.5 42.7 9.2 17.1 87.5 34.9 30.8 194.4 131.8 13.5 26.1 11.0 127.6 5.8 521.4 411.2 6.9 359.0 108.5 118.6 171.8 2.9 2.1 1.2 13.5 1281.3 11.4 33.5 5.3 4.8 123.7 24.3 1.2 0.7 27.7 0.7 109.5 1.0 0.5 409.7 14.4 174.9 11.0 2404.9 27.8 0.6 0.4 1.0 352.7 0.5 0.3 0.7 31.6 0.7 4.2 0.3 14.0 0.6 3.3 0.5 0.4 2.5 53.5 2.3 1.8 23.0 2.1 1.0 141.7 345.6 56.6 66.6 160.1 1.6 0.8 1.2 102.4 0.7 56.8 0.9 0.3 0.2 0.3 0.1 0.3 0.4 0.3 0.3 0.1 0.6 0.4 0.4 0.3 0.3 0.2 0.7 0.2 0.0 6.4 6.9 9.6 8.6 6.8 10.2 12.2 11.4 9.3 11.1 9.2 13.5 104.5 6.4 15.9 13.1 1.5 60.9 4.2 44.7 26.7 1.1 5.9 59.7 22.5 10.0 62.7 5.5 0.0 57.9 1.0 0.3 1.9 23.7 450.8 95.4 93.2 43.9 0.0 0.0 1.0 1.2 101.5 921.6 16.8 18.4 1.3 44.3 53.6 0.9 9.4 0.0 0.3 0.8 30.5 2.2 121.5 353.6 77.0 9.7 144.1 3.7 2.0 101.4 0.0 0.0 0.0 13.5 0.0 34.6 5.8 3.6 0.0 0.1 112.4 2.5 19.7 177.7 198.4 6.9 4.9 11.9 51.7 27.9 9.0 23.0 0.1 1.9 CCND1 "BCL1, D11S287E, PRAD1, U21B31" ENSG00000110092 "Cyclin D1" P24385 11 69641156-69654474 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, Transcription, Transcription regulation" "Cyclin, Repressor" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 499.7;Ductal cells: 504.0;Pancreatic endocrine cells: 622.1;Urothelial cells: 412.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "myeloid DC: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "U-266/70: 874.2;WM-115: 1239.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000024, HPA027802" Uncertain Supported Nucleoplasm Yes No "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 18: Non-specific - Mitochondria" "Cluster 17: WM-115 - Nervous system development" "Cluster 1: Pancreatic cells - Digestion" Nucleoplasm "CAB000024: AB_563678, HPA027802: AB_2672390" "unprognostic (4.90e-2)" "unprognostic (1.54e-1)" "unprognostic (7.62e-2)" "unprognostic (1.39e-2)" "unprognostic (2.18e-1)" "prognostic unfavorable (5.51e-4)" "unprognostic (1.38e-1)" "unprognostic (2.53e-2)" "unprognostic (9.46e-2)" "unprognostic (4.84e-3)" "prognostic unfavorable (1.96e-4)" "unprognostic (4.39e-2)" "unprognostic (2.61e-3)" "unprognostic (4.38e-3)" "unprognostic (1.16e-1)" "unprognostic (6.40e-3)" "unprognostic (2.57e-1)" 55.6 29.2 12.1 10.0 14.6 1.5 40.2 15.0 11.9 17.0 33.4 19.8 22.7 14.8 27.6 72.9 30.8 19.5 64.9 10.8 14.6 32.2 107.3 61.1 10.5 17.5 15.5 4.6 86.3 82.7 25.7 63.7 18.3 53.3 17.2 3.2 30.4 50.4 3.6 120.3 16.0 23.3 15.9 37.2 52.7 3.2 21.7 9.9 45.5 5.2 19.0 29.5 43.9 24.0 467.3 183.0 59.5 1.8 178.3 186.7 127.4 717.5 264.9 82.1 47.6 206.9 349.9 0.1 317.6 375.5 137.2 332.1 6.5 195.2 146.0 1.2 36.5 0.3 46.7 211.7 43.3 3.3 6.7 106.5 37.9 116.0 44.0 192.5 142.1 0.2 0.6 1.3 654.2 197.1 0.4 26.6 109.0 190.7 198.3 1.2 187.9 11.3 379.4 282.8 10.0 231.4 9.2 167.7 458.4 143.5 102.6 9.5 600.4 399.5 111.0 176.1 496.2 874.2 559.4 1.5 341.6 5.9 1239.0 0.2 0.0 0.0 0.2 0.0 0.0 0.9 0.1 0.0 1.1 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 12.1 14.6 15.0 11.9 10.8 14.6 17.5 15.5 18.3 15.9 21.7 24.0 84.6 182.7 115.6 0.3 8.3 202.5 234.7 499.7 133.1 2.3 163.4 140.0 80.0 92.9 271.6 125.0 2.1 10.9 2.4 44.8 31.3 504.0 0.4 104.2 23.5 141.0 56.5 2.5 0.5 142.6 1.2 67.6 127.4 199.5 29.1 0.0 98.2 165.2 75.0 0.0 2.2 42.6 75.3 18.8 61.9 2.0 4.1 23.6 51.6 17.8 2.4 79.1 0.0 49.8 0.3 622.1 118.0 57.6 0.5 262.0 19.4 57.1 85.9 3.1 131.5 13.0 184.8 0.5 23.4 292.3 351.1 2.5 8.8 3.4 82.2 412.6 CCNE1 CCNE ENSG00000105173 "Cyclin E1" P24864 19 29811991-29824312 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 35.8;placenta: 30.8" "Cell type enriched" "Detected in many" 14 "Extravillous trophoblasts: 1756.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "BEWO: 293.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000308, CAB016682, HPA018169" Approved Enhanced Nucleoplasm Yes Yes "Cluster 43: B-cells - Humoral immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "CAB000308: , CAB016682: AB_1614564, HPA018169: AB_1847384" "unprognostic (2.90e-3)" "unprognostic (1.33e-2)" "unprognostic (1.47e-3)" "prognostic unfavorable (6.35e-6)" "unprognostic (5.78e-2)" "unprognostic (4.77e-2)" "prognostic unfavorable (3.89e-5)" "unprognostic (1.26e-3)" "unprognostic (3.14e-3)" "prognostic unfavorable (2.97e-4)" "unprognostic (3.29e-2)" "unprognostic (7.07e-2)" "unprognostic (1.11e-16)" "unprognostic (5.61e-2)" "unprognostic (1.92e-1)" "unprognostic (6.63e-2)" "unprognostic (1.46e-1)" 1.2 5.7 1.9 4.3 2.1 35.8 0.8 2.8 2.7 1.0 0.9 3.9 3.0 1.4 0.6 4.4 0.9 1.0 2.3 2.0 2.5 1.0 0.7 1.1 6.1 2.0 2.1 0.8 1.8 2.8 0.9 30.8 2.0 1.0 4.7 2.0 1.5 1.4 2.1 4.1 2.5 2.2 1.7 4.2 2.1 12.1 2.5 4.5 1.6 1.8 7.8 3.0 1.8 2.3 15.6 31.8 24.3 34.0 5.2 6.0 293.1 24.7 5.3 10.8 13.2 33.0 31.2 13.3 55.9 11.1 14.0 4.9 28.8 12.8 15.2 41.9 17.7 11.2 30.0 34.5 4.1 44.0 28.7 6.2 7.1 14.8 1.9 3.4 13.3 13.2 45.6 5.8 16.8 24.4 24.5 13.0 40.1 36.2 7.2 36.2 28.6 10.1 8.4 24.6 20.5 17.4 35.4 42.7 3.9 35.4 9.5 32.7 8.0 25.0 92.8 14.9 16.9 24.1 18.2 91.6 13.8 5.6 13.7 0.0 0.0 0.0 0.1 0.5 0.3 0.6 0.1 0.0 0.4 0.0 0.0 0.2 0.4 0.0 0.5 0.0 0.3 0.1 1.9 2.1 2.8 2.7 2.0 2.5 2.0 2.1 2.0 1.7 2.5 2.3 3.1 0.0 0.6 0.7 4.8 4.8 1.5 0.3 2.2 2.9 8.2 11.3 3.1 0.0 1.4 0.0 0.0 122.4 3.7 3.5 0.0 0.4 14.6 7.5 4.1 1.9 3.0 30.7 2.9 0.7 1756.5 6.0 5.6 20.1 0.0 4.6 1.4 0.2 43.4 3.3 5.1 3.3 0.0 1.0 2.5 3.6 1.2 4.2 1.8 0.0 0.2 1.7 0.0 2.5 1.3 1.4 2.2 2.2 18.4 2.2 1.0 0.4 0.1 1.1 6.6 4.1 3.4 25.0 17.6 8.5 6.0 115.7 4.5 6.9 4.9 3.5 CCNF "FBX1, FBXO1" ENSG00000162063 "Cyclin F" P41002 16 2429394-2458854 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" Cyclin "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 15.1" "Cell type enhanced" "Detected in many" "Erythroid cells: 37.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA060596, HPA070495, HPA071600" Enhanced Supported Centrosome NA Yes "Cluster 40: NK-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Centrosome "HPA060596: AB_2684329, HPA070495: AB_2686273, HPA071600: AB_2686424" "unprognostic (3.87e-2)" "unprognostic (2.21e-2)" "unprognostic (1.57e-3)" "unprognostic (3.70e-3)" "unprognostic (1.24e-1)" "unprognostic (1.13e-1)" "prognostic unfavorable (7.46e-7)" "unprognostic (2.45e-2)" "unprognostic (1.75e-2)" "unprognostic (1.99e-1)" "unprognostic (1.01e-2)" "unprognostic (1.58e-2)" "unprognostic (0.00e+0)" "unprognostic (1.22e-2)" "unprognostic (1.10e-2)" "unprognostic (4.25e-2)" "unprognostic (2.74e-1)" 1.4 1.0 2.5 3.8 2.1 7.3 1.9 2.9 2.7 1.3 0.0 2.0 2.8 0.8 2.0 4.0 0.8 0.8 0.6 2.4 2.0 0.6 0.7 1.0 7.4 1.5 2.0 1.0 0.8 0.5 0.8 2.5 1.3 1.6 2.0 0.8 2.1 1.1 1.3 4.8 2.1 1.1 0.8 2.2 1.6 2.7 2.6 15.1 0.7 1.3 9.6 1.7 1.5 1.7 21.0 32.4 31.3 28.9 2.2 2.9 23.8 24.1 12.2 34.2 26.1 64.6 25.6 42.3 8.0 14.1 10.2 33.1 52.2 19.6 16.4 30.9 23.4 46.1 35.3 20.4 2.3 30.4 30.7 2.0 2.5 24.1 11.7 4.4 25.5 36.5 52.0 28.5 17.6 45.6 46.1 25.0 31.2 22.6 13.2 76.2 35.1 39.5 9.5 9.3 29.8 17.0 36.0 32.8 6.4 15.6 34.3 16.6 18.1 19.1 46.7 13.5 27.1 16.4 20.9 74.5 5.6 31.8 26.9 0.0 0.3 0.0 0.7 0.1 0.4 0.6 0.4 0.9 0.1 0.4 0.3 0.4 0.0 1.3 0.3 0.5 0.5 0.6 2.5 2.1 2.9 2.7 2.4 2.0 1.5 2.0 1.3 0.8 2.6 1.7 0.9 0.0 3.9 3.3 2.7 2.8 2.7 1.4 6.2 5.3 2.4 2.0 1.9 0.0 1.6 1.8 12.5 7.0 3.7 2.4 0.0 1.2 0.9 1.0 2.7 2.2 1.2 37.5 5.7 0.6 12.2 2.2 5.6 1.0 1.3 8.9 2.5 0.9 6.1 8.4 5.6 2.6 4.1 2.4 1.6 0.0 1.8 1.5 5.4 0.0 0.8 0.9 2.1 1.0 1.0 1.1 0.3 2.6 7.2 1.9 0.9 0.2 0.3 1.6 0.0 0.8 2.7 3.9 5.7 3.5 1.1 1.9 3.4 1.7 4.7 1.6 CCRL2 "ACKR5, CKRX, CRAM-A, CRAM-B, HCR" ENSG00000121797 "C-C motif chemokine receptor like 2" O00421 3 46407166-46412997 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 35.0;Erythroid cells: 26.5;Hofbauer cells: 42.7;Kupffer cells: 22.1;Langerhans cells: 36.5;Macrophages: 56.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 21.0;OE19: 8.4;PC-3: 15.3;RT4: 8.3;TIME: 15.4;U-266/84: 8.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA043238 Approved NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 36: HEL - Hemostasis" "Cluster 41: Macrophages - Immune response" "HPA043238: AB_10794924" "unprognostic (3.94e-1)" "unprognostic (7.02e-2)" "prognostic favorable (3.72e-5)" "unprognostic (1.64e-1)" "unprognostic (2.67e-1)" "unprognostic (1.12e-1)" "unprognostic (1.46e-1)" "unprognostic (1.62e-1)" "unprognostic (4.10e-2)" "unprognostic (4.17e-2)" "unprognostic (9.73e-2)" "unprognostic (1.98e-2)" "unprognostic (5.17e-2)" "unprognostic (1.78e-1)" "unprognostic (3.04e-2)" "unprognostic (2.57e-1)" "prognostic favorable (9.67e-5)" 11.7 1.6 2.1 11.4 2.1 9.0 8.4 2.2 3.7 2.3 2.2 11.5 11.7 1.2 0.6 0.9 1.1 5.5 2.7 2.1 2.2 2.2 4.4 12.4 4.9 2.8 2.3 0.5 1.5 0.8 0.8 5.1 3.1 0.8 10.4 0.2 0.9 0.8 1.1 0.7 12.1 2.5 2.6 8.5 5.5 0.3 2.9 7.7 1.3 1.1 3.8 6.0 1.1 3.3 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 1.2 0.0 0.2 0.0 0.0 2.8 0.0 0.0 0.3 0.7 4.6 0.0 21.0 0.0 0.0 0.0 1.4 0.2 0.0 0.0 5.0 0.2 0.0 7.2 4.2 2.8 0.1 5.0 0.0 1.6 2.6 0.0 8.4 15.3 0.4 0.3 0.0 0.0 8.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.5 15.4 0.6 0.3 0.7 0.3 0.0 8.6 0.2 7.5 6.5 0.0 8.7 15.4 4.3 2.8 22.1 3.4 1.7 1.6 4.7 9.9 3.9 1.0 2.5 2.6 6.7 10.1 3.0 4.7 5.0 2.1 2.1 2.2 3.7 2.1 2.2 2.8 2.3 3.1 2.6 2.9 3.3 35.0 0.0 4.7 0.0 4.4 2.0 0.2 0.2 0.0 0.0 0.4 0.4 1.1 1.5 1.2 0.0 0.0 0.3 4.5 19.5 0.0 0.6 0.1 0.1 0.2 12.1 0.0 26.5 0.0 8.8 1.2 1.4 4.6 0.1 9.5 0.1 6.4 0.4 42.7 0.0 0.0 16.6 0.0 22.1 36.5 0.0 0.0 56.2 1.8 1.9 6.7 0.0 0.0 0.0 0.0 9.8 12.4 0.0 4.2 0.2 17.2 0.2 0.6 0.0 0.0 0.6 0.5 0.0 0.0 0.0 1.1 2.5 6.4 0.4 9.2 1.1 CD1E ENSG00000158488 "CD1e molecule" P15812 1 158353696-158357553 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 69 "lymphoid tissue: 962.6" "Cell type enriched" "Detected in some" 13 "Langerhans cells: 549.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 14 "myeloid DC: 62.5" "Lineage enriched" "Detected in many" 14 "dendritic cells: 62.5" "Cell line enriched" "Detected in some" 43 "MOLT-4: 1276.2" "Not detected" "Not detected" "HPA057769, HPA070634" Uncertain Supported "Nucleoli,Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 41: Macrophages - Immune response" "Golgi apparatus" Nucleoli "HPA057769: AB_2683522, HPA070634: " "unprognostic (7.94e-3)" "unprognostic (1.85e-5)" "unprognostic (1.47e-2)" "unprognostic (1.64e-2)" "unprognostic (1.76e-2)" "unprognostic (1.29e-2)" "unprognostic (2.33e-1)" "unprognostic (1.54e-3)" "unprognostic (1.24e-1)" "unprognostic (1.74e-1)" "unprognostic (1.60e-1)" "unprognostic (8.55e-2)" "unprognostic (1.69e-2)" "unprognostic (1.50e-1)" "unprognostic (2.49e-1)" "unprognostic (8.50e-2)" "unprognostic (2.45e-1)" 0.7 0.5 0.0 4.4 0.0 0.0 1.8 0.0 0.0 2.1 0.0 2.1 2.2 1.1 0.4 7.9 0.9 4.8 1.0 0.0 0.0 0.8 1.5 3.1 6.4 0.0 0.0 0.6 0.3 0.5 0.1 0.0 0.0 1.1 5.6 0.0 1.5 0.6 0.4 13.9 2.8 0.9 0.0 5.1 4.7 0.5 0.0 962.6 0.8 0.2 9.9 2.8 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 29.8 0.1 0.0 0.0 0.5 1276.2 0.0 0.3 0.0 0.0 0.6 0.0 0.3 0.0 0.0 0.8 0.0 0.0 0.9 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.1 2.5 0.2 0.0 0.0 0.0 62.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 3.2 0.5 0.0 0.8 8.4 0.0 0.0 0.6 0.0 0.1 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.7 0.0 1.3 0.0 0.0 0.0 0.7 0.0 0.0 1.3 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 4.8 549.5 0.0 0.0 41.7 8.8 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.5 0.0 7.1 0.1 0.7 0.0 0.0 0.0 CD247 "CD3H, CD3Q, CD3Z" ENSG00000198821 "CD247 molecule" P20963 1 167430640-167518610 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Adaptive immunity, Host-virus interaction, Immunity" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "bone marrow: 49.0;lymphoid tissue: 179.4" "Group enriched" "Detected in many" 9 "dendritic cells: 492.1;NK-cells: 727.1;T-cells: 247.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 25 "gdT-cell: 376.4;MAIT T-cell: 208.9;memory CD4 T-cell: 190.0;memory CD8 T-cell: 219.7;naive CD4 T-cell: 237.8;naive CD8 T-cell: 195.1;NK-cell: 225.3;T-reg: 254.5" "Group enriched" "Detected in all" 32 "NK-cells: 225.3;T-cells: 376.4" "Group enriched" "Detected in some" 25 "HDLM-2: 155.9;JURKAT: 113.1;MOLT-4: 167.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB004651, HPA008750" Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB004651: AB_425347, HPA008750: AB_1857863" "prognostic favorable (9.12e-4)" "unprognostic (3.21e-3)" "unprognostic (7.09e-3)" "prognostic favorable (8.63e-6)" "unprognostic (1.99e-2)" "prognostic favorable (3.98e-4)" "unprognostic (1.79e-2)" "unprognostic (1.11e-2)" "unprognostic (5.46e-3)" "unprognostic (9.73e-3)" "unprognostic (1.33e-2)" "unprognostic (2.50e-1)" "prognostic unfavorable (9.94e-6)" "unprognostic (1.60e-1)" "unprognostic (5.33e-2)" "unprognostic (4.02e-2)" "unprognostic (5.94e-3)" 3.2 1.7 2.3 25.3 2.3 49.0 1.9 2.2 2.5 1.9 1.9 4.3 7.1 2.3 3.1 2.1 1.8 5.5 1.3 2.3 2.3 2.0 5.4 10.9 57.7 2.3 2.2 0.8 0.8 0.5 0.8 1.4 2.2 1.8 4.6 0.2 2.4 1.6 1.4 1.1 14.3 1.5 2.1 40.2 7.0 0.4 2.9 179.4 2.5 0.9 36.4 7.3 1.9 2.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 155.9 0.3 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 113.1 0.0 0.1 0.0 0.0 167.1 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.2 0.3 0.8 0.0 0.0 0.0 8.3 1.0 0.4 376.4 1.4 208.9 9.3 190.0 219.7 1.5 4.9 237.8 195.1 8.7 225.3 1.2 2.8 254.5 231.2 2.3 2.3 2.2 2.5 2.3 2.3 2.3 2.2 2.2 2.1 2.9 2.5 3.4 3.2 16.0 3.3 8.2 1.5 0.1 0.0 0.6 0.4 3.5 3.2 0.6 1.5 1.3 0.0 0.0 0.1 492.1 0.4 0.0 0.5 0.2 0.7 0.8 1.8 0.0 14.7 8.8 0.0 0.1 2.2 6.1 1.1 6.3 0.4 7.1 1.4 0.3 3.3 9.4 0.5 0.0 7.8 1.4 0.2 0.0 5.9 3.6 14.0 7.6 0.1 727.1 0.5 3.7 0.0 1.2 0.0 51.9 0.1 0.2 1.3 2.2 0.2 0.0 0.9 1.2 0.1 2.5 1.4 0.6 0.1 247.2 0.0 0.1 0.1 CD3D T3D ENSG00000167286 "CD3d molecule" P04234 11 118339075-118342705 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "FDA approved drug targets, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 30 "lymphoid tissue: 906.7" "Group enriched" "Detected in many" 14 "dendritic cells: 231.0;T-cells: 665.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in all" 52 "gdT-cell: 1462.4;MAIT T-cell: 990.0;memory CD4 T-cell: 1206.1;memory CD8 T-cell: 1368.7;naive CD4 T-cell: 1091.4;naive CD8 T-cell: 1338.9;T-reg: 1660.4" "Lineage enriched" "Detected in all" 66 "T-cells: 1660.4" "Group enriched" "Detected in some" 4 "JURKAT: 621.5;MOLT-4: 1299.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB013055, HPA071778" Enhanced Uncertain "Endoplasmic reticulum" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Endoplasmic reticulum" "CAB013055: , HPA071778: " "prognostic favorable (3.00e-4)" "prognostic favorable (8.46e-5)" "unprognostic (1.05e-2)" "prognostic favorable (1.73e-7)" "unprognostic (6.00e-2)" "prognostic favorable (1.70e-4)" "unprognostic (3.82e-1)" "unprognostic (2.40e-2)" "unprognostic (2.24e-3)" "unprognostic (1.01e-2)" "unprognostic (5.69e-2)" "unprognostic (2.55e-1)" "prognostic unfavorable (3.07e-5)" "unprognostic (9.00e-2)" "unprognostic (2.02e-1)" "unprognostic (3.66e-2)" "prognostic favorable (6.16e-4)" 4.1 3.8 0.3 77.5 0.4 28.6 9.9 0.4 1.4 5.2 0.7 18.8 21.7 3.6 5.7 7.6 4.5 15.7 3.7 0.3 0.6 2.3 7.9 20.6 222.7 1.1 0.4 3.2 1.3 0.9 0.8 1.2 0.6 5.9 22.4 0.3 8.3 3.1 2.5 4.0 30.1 3.9 0.7 60.9 23.8 2.4 0.5 906.7 3.8 1.4 166.9 26.7 3.6 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 621.5 49.8 0.0 0.0 0.0 1299.8 237.2 1.2 0.0 0.0 0.7 0.1 0.5 0.0 0.0 0.4 0.0 0.0 1.9 0.0 0.2 0.8 0.0 0.5 0.0 1.5 1.1 0.0 0.9 1.1 0.4 0.0 0.1 0.0 10.1 5.3 4.6 1462.4 3.3 990.0 9.6 1206.1 1368.7 5.0 3.7 1091.4 1338.9 25.1 4.2 5.3 6.0 1660.4 1138.7 0.3 0.4 0.4 1.4 0.3 0.6 1.1 0.4 0.6 0.7 0.5 0.8 5.9 6.4 29.6 0.0 18.6 15.3 0.3 0.0 1.8 0.0 5.4 6.7 2.8 7.2 2.6 3.7 0.0 0.4 231.0 0.9 0.0 1.3 0.4 0.8 0.8 5.0 1.2 16.8 0.0 0.0 0.0 8.3 21.4 0.9 12.6 0.0 7.9 3.1 0.6 0.0 0.0 0.2 0.0 14.9 28.4 0.7 0.0 14.2 12.4 1.0 25.0 0.0 32.0 0.0 0.0 0.1 0.2 0.0 21.0 0.3 0.0 3.4 1.5 0.0 0.0 2.5 5.8 0.1 1.2 1.4 11.8 0.3 665.7 0.0 1.1 0.2 CD3G ENSG00000160654 "CD3g molecule" P09693 11 118344344-118355161 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "lymphoid tissue: 94.7" "Group enriched" "Detected in many" 11 "dendritic cells: 139.6;T-cells: 294.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 21 "gdT-cell: 229.0;MAIT T-cell: 135.6;memory CD4 T-cell: 187.3;memory CD8 T-cell: 197.3;naive CD4 T-cell: 192.6;naive CD8 T-cell: 241.7;T-reg: 200.0" "Lineage enriched" "Detected in many" 26 "T-cells: 241.7" "Group enriched" "Detected in some" 52 "JURKAT: 70.9;MOLT-4: 193.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB017520, HPA038494" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Cytosol" "CAB017520: AB_831094, HPA038494: AB_2676044" "prognostic favorable (6.33e-4)" "prognostic favorable (2.61e-4)" "unprognostic (4.58e-3)" "unprognostic (3.12e-5)" "unprognostic (6.30e-2)" "prognostic favorable (3.00e-4)" "unprognostic (1.98e-2)" "unprognostic (1.54e-2)" "unprognostic (8.25e-3)" "unprognostic (1.08e-3)" "unprognostic (1.54e-2)" "unprognostic (2.19e-1)" "prognostic unfavorable (9.33e-5)" "unprognostic (1.60e-1)" "unprognostic (2.37e-2)" "unprognostic (4.13e-2)" "unprognostic (2.10e-3)" 0.7 0.8 0.6 10.5 0.8 1.3 1.0 1.1 0.8 0.7 1.1 2.3 3.3 0.5 0.6 1.4 0.9 2.5 0.5 0.5 0.4 0.6 1.6 2.8 27.9 0.9 0.6 0.4 0.5 0.2 0.0 0.3 0.8 0.9 2.7 0.4 1.6 0.3 10.5 0.9 4.6 0.6 0.3 11.5 4.1 0.4 0.8 94.7 0.6 0.3 20.4 3.0 0.4 1.9 0.2 0.2 0.1 0.2 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.2 0.2 0.7 0.2 0.0 0.3 0.2 0.0 0.0 0.0 0.6 0.6 0.0 0.4 0.2 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.1 0.0 70.9 2.5 0.3 0.0 0.6 193.8 1.3 0.2 0.0 0.1 0.2 0.0 0.3 0.0 0.1 0.5 0.2 0.0 1.1 0.1 0.0 0.6 0.2 0.0 0.2 0.2 0.2 0.1 0.2 0.7 0.3 0.2 0.2 0.1 9.2 1.2 1.2 229.0 0.6 135.6 0.8 187.3 197.3 0.6 0.9 192.6 241.7 6.4 1.4 1.2 1.5 200.0 90.4 0.6 0.8 1.1 0.8 0.5 0.4 0.9 0.6 0.8 0.3 0.8 1.9 3.2 3.2 6.9 0.0 7.8 2.3 0.1 0.0 1.8 0.2 2.0 2.9 0.8 1.5 1.9 0.0 0.0 0.1 139.6 0.4 0.0 0.3 1.0 0.4 0.4 1.4 0.0 3.4 0.1 0.0 0.0 2.3 13.7 0.4 6.3 0.0 4.2 1.7 0.1 0.0 0.1 0.2 0.0 3.8 5.8 1.4 0.0 7.7 5.4 1.0 8.1 0.0 14.4 0.0 0.3 0.0 0.1 0.0 18.5 0.0 0.0 0.6 0.7 0.8 0.0 1.3 1.6 0.2 0.4 0.6 2.4 0.3 294.0 0.1 0.3 0.0 CD40LG "CD154, CD40L, gp39, hCD40L, HIGM1, IMD3, TNFSF5, TRAP" ENSG00000102245 "CD40 ligand" P29965 X 136648158-136660390 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Cytokine "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 15.5" "Cell type enriched" "Detected in some" 8 "T-cells: 76.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "gdT-cell: 26.3;MAIT T-cell: 64.1;memory CD4 T-cell: 80.5;naive CD4 T-cell: 76.1" "Lineage enriched" "Detected in many" 39 "T-cells: 80.5" "Cell line enriched" "Detected in some" 15 "MOLT-4: 23.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045827, HPA072480" Enhanced Approved "Golgi apparatus,Plasma membrane" "Secreted to blood" NA NA 776000 20000 "Cluster 32: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Golgi apparatus, Plasma membrane" "HPA045827: AB_10959606, HPA072480: " "unprognostic (1.94e-5)" "unprognostic (1.24e-2)" "unprognostic (3.26e-1)" "unprognostic (1.27e-3)" "unprognostic (4.71e-2)" "unprognostic (3.56e-5)" "unprognostic (3.66e-2)" "unprognostic (5.48e-3)" "unprognostic (2.77e-1)" "unprognostic (2.14e-4)" "unprognostic (1.87e-1)" "unprognostic (1.55e-1)" "unprognostic (6.70e-4)" "unprognostic (2.15e-1)" "unprognostic (5.19e-2)" "unprognostic (2.36e-3)" "unprognostic (2.92e-2)" 0.8 0.3 0.1 7.9 0.0 1.9 1.1 0.2 0.2 0.9 0.2 1.9 1.8 0.3 0.2 1.0 0.4 2.0 0.2 0.1 0.2 0.4 1.0 2.4 15.5 0.1 0.1 0.3 0.0 0.0 0.0 0.1 0.2 0.8 3.1 0.0 0.6 0.3 0.1 0.6 3.8 0.6 0.0 4.9 2.0 0.3 0.1 15.5 0.5 0.2 14.8 2.5 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 23.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.1 0.3 26.3 0.1 64.1 0.1 80.5 11.7 0.2 0.0 76.1 0.7 1.3 0.8 0.1 0.1 10.5 13.6 0.1 0.0 0.2 0.2 0.1 0.2 0.1 0.1 0.2 0.0 0.1 0.2 0.6 0.0 2.4 0.0 2.4 1.3 0.0 0.0 0.0 0.0 0.4 0.5 0.3 0.0 0.6 0.0 0.0 0.0 4.5 0.0 0.0 0.0 3.9 0.0 0.0 0.6 0.0 1.7 0.0 0.0 0.0 0.6 2.6 0.0 1.3 0.0 1.1 0.3 0.1 0.0 0.0 0.0 0.0 0.6 4.0 8.9 0.0 2.9 1.8 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.4 0.0 0.0 0.0 0.6 0.7 0.0 0.0 0.1 2.0 0.0 76.6 0.0 0.0 0.1 CD79A "IGA, MB-1" ENSG00000105369 "CD79a molecule" P11912 19 41877279-41881372 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 152.3;lymphoid tissue: 545.2" "Group enriched" "Detected in some" 5 "B-cells: 1186.4;Plasma cells: 956.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 38 "memory B-cell: 1273.8;naive B-cell: 1457.5" "Lineage enriched" "Detected in all" 40 "B-cells: 1457.5" "Group enriched" "Detected in some" 22 "Daudi: 1598.7;REH: 491.0;U-698: 1366.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000019, HPA056444" Enhanced NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "CAB000019: AB_2244527, HPA056444: " "prognostic favorable (8.45e-5)" "unprognostic (1.63e-3)" "unprognostic (4.13e-3)" "unprognostic (1.31e-3)" "unprognostic (2.02e-1)" "prognostic favorable (1.18e-5)" "unprognostic (1.23e-2)" "unprognostic (8.11e-3)" "unprognostic (9.41e-3)" "unprognostic (1.12e-2)" "unprognostic (2.53e-1)" "unprognostic (2.32e-1)" "prognostic unfavorable (2.15e-5)" "unprognostic (6.08e-2)" "unprognostic (3.39e-1)" "unprognostic (1.17e-1)" "unprognostic (1.46e-1)" 4.8 4.9 0.2 213.4 0.2 47.2 9.5 0.2 0.4 3.6 0.1 47.3 37.9 2.4 1.4 9.9 1.8 13.0 2.9 0.1 0.1 3.4 2.6 8.9 482.4 0.3 0.2 3.7 0.6 0.1 0.3 1.2 0.2 4.3 28.9 0.0 28.5 2.2 0.7 0.4 152.3 2.2 0.6 286.5 76.9 2.4 0.2 93.7 8.1 0.4 545.2 32.3 1.9 0.3 1.1 0.8 0.3 0.1 0.2 0.7 0.2 0.2 0.0 0.3 0.0 0.0 0.1 1598.7 1.2 0.0 0.1 0.0 0.2 0.2 0.0 0.5 0.7 2.7 0.0 1.7 0.2 2.6 1.8 0.5 0.6 0.2 0.0 0.0 0.0 8.0 3.1 0.4 0.1 1.1 1.6 9.9 0.1 0.1 0.4 491.0 0.8 2.5 0.1 0.0 0.5 0.5 0.8 0.5 1.3 0.0 0.0 4.8 1.6 0.1 4.3 0.3 0.8 7.8 1.4 1366.7 0.0 52.1 0.1 12.4 1.5 6.9 1.7 1.8 0.7 1273.8 4.1 2.1 2.5 1457.5 4.9 26.3 4.6 2.6 4.3 36.3 10.4 62.7 0.2 0.2 0.2 0.4 0.1 0.1 0.3 0.2 0.2 0.6 0.2 0.3 0.2 0.0 2.4 0.0 1186.4 1.8 0.5 0.5 0.6 0.0 0.7 0.9 0.2 1.5 0.2 0.0 0.0 0.2 18.2 0.7 0.0 1.8 0.2 0.1 0.3 0.5 0.0 10.5 0.0 25.6 0.4 2.2 6.6 0.2 0.0 0.4 2.2 1.0 0.8 0.0 0.0 0.4 0.0 4.1 1.4 0.0 0.3 5.3 138.7 0.0 6.3 0.0 15.5 0.0 0.0 181.7 0.4 0.4 956.7 0.3 0.2 0.9 0.0 0.0 0.0 0.2 0.7 0.3 0.6 0.9 1.4 0.1 23.5 0.2 5.3 0.2 CD8A CD8 ENSG00000153563 "CD8a molecule" P01732 2 86784610-86808396 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 16 "lymphoid tissue: 369.0" "Group enriched" "Detected in many" 4 "dendritic cells: 111.7;T-cells: 242.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 14 "MAIT T-cell: 234.4;memory CD8 T-cell: 523.0;naive CD8 T-cell: 476.8" "Lineage enriched" "Detected in many" 19 "T-cells: 523.0" "Cell line enhanced" "Detected in some" "JURKAT: 4.0;MOLT-4: 15.2;RPMI-8226: 3.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000012, HPA037756, CAB075722" Enhanced Supported "Plasma membrane" "Intracellular and membrane" NA NA 490000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "Plasma membrane" "CAB000012: AB_2075537, CAB075722: AB_2665709, HPA037756: AB_2675648" "unprognostic (1.29e-3)" "prognostic favorable (4.54e-4)" "unprognostic (9.26e-3)" "prognostic favorable (6.15e-6)" "unprognostic (7.28e-2)" "unprognostic (2.79e-3)" "unprognostic (1.03e-2)" "unprognostic (2.00e-2)" "unprognostic (1.35e-2)" "unprognostic (4.50e-3)" "unprognostic (1.09e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (1.91e-5)" "unprognostic (1.36e-1)" "unprognostic (1.48e-1)" "unprognostic (6.74e-2)" "unprognostic (1.56e-2)" 5.3 4.6 2.1 21.2 2.8 22.5 4.7 1.9 3.0 3.8 1.4 4.9 11.8 3.0 3.6 4.4 4.0 9.8 2.3 2.1 2.1 1.8 7.4 10.5 45.0 2.8 2.1 2.5 2.6 1.1 1.5 0.6 2.5 3.4 5.9 0.2 8.3 1.9 0.8 1.3 20.7 2.4 2.2 117.1 16.4 1.0 2.3 369.0 4.4 0.4 21.4 9.1 4.0 2.1 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.3 0.0 1.4 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 4.0 0.0 0.2 0.0 0.6 15.2 0.9 0.5 0.1 0.2 0.1 0.7 3.3 0.0 0.3 0.7 1.9 0.1 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.5 0.1 0.0 0.1 0.2 0.7 0.0 0.0 0.0 1.4 0.8 0.3 30.0 0.3 234.4 0.6 2.3 523.0 0.4 0.6 2.2 476.8 4.3 27.9 0.9 1.2 0.8 152.4 2.1 2.8 1.9 3.0 2.1 2.1 2.8 2.1 2.5 2.2 2.3 2.1 2.2 0.0 4.6 0.0 5.7 2.0 0.2 0.0 0.0 0.3 1.5 1.5 3.4 1.5 0.6 0.0 0.0 0.0 111.7 0.2 0.0 0.2 0.3 0.5 0.3 1.3 0.0 7.8 4.2 0.0 0.0 2.6 8.2 0.4 2.5 0.0 6.4 2.3 0.1 0.0 3.1 0.3 0.0 1.9 11.5 0.2 0.0 6.6 0.0 1.0 5.9 0.1 38.1 0.0 0.2 0.0 0.0 0.0 30.8 0.2 0.0 0.4 1.5 0.4 0.0 1.1 1.4 0.4 0.4 1.1 1.8 0.1 242.4 0.0 0.6 0.1 CDC34 "E2-CDC34, UBC3, UBE2R1" ENSG00000099804 "Cell division cycle 34, ubiqiutin conjugating enzyme" P49427 19 531760-542092 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 249.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002382, CAB005109, CAB047311, HPA074334" Approved Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nuclear speckles" Cytosol "CAB005109: AB_2276050, CAB047311: , HPA002382: AB_1846370, HPA074334: " "unprognostic (4.65e-2)" "unprognostic (2.02e-1)" "unprognostic (1.41e-1)" "unprognostic (8.72e-2)" "unprognostic (2.84e-1)" "unprognostic (5.73e-2)" "prognostic unfavorable (7.57e-4)" "unprognostic (2.20e-1)" "unprognostic (3.11e-1)" "unprognostic (3.83e-2)" "unprognostic (2.09e-2)" "unprognostic (3.06e-2)" "unprognostic (3.02e-2)" "unprognostic (8.87e-3)" "unprognostic (9.68e-2)" "unprognostic (7.82e-3)" "unprognostic (3.33e-2)" 35.1 36.7 52.0 13.3 51.2 34.5 34.2 51.5 63.0 36.9 47.5 62.5 17.8 33.5 14.1 40.5 33.6 10.1 80.0 52.7 48.7 32.1 88.0 32.1 12.5 51.0 50.7 35.6 58.5 18.7 43.4 29.2 50.8 36.9 11.5 28.2 34.2 19.3 105.0 51.8 27.6 18.5 48.2 31.0 38.6 100.2 52.7 16.4 26.7 63.2 9.7 43.7 34.2 52.7 54.8 54.6 66.4 54.7 29.2 28.4 68.5 47.8 36.1 50.2 51.9 86.1 32.8 29.5 49.3 34.1 30.1 36.9 52.1 40.2 25.0 49.2 146.0 27.8 35.5 94.5 73.6 39.0 32.4 36.4 58.9 42.2 43.6 38.8 60.6 41.2 120.3 57.5 33.8 80.7 53.3 53.6 85.3 39.4 51.7 49.1 35.1 51.2 38.0 32.4 87.2 65.9 41.5 42.1 85.2 53.2 34.0 57.4 50.5 36.5 43.7 86.2 65.2 57.7 47.3 40.1 50.0 55.6 38.8 3.2 2.5 4.7 1.6 2.7 1.1 2.3 2.1 2.9 2.0 1.0 1.6 1.6 8.2 1.2 3.5 1.6 2.5 1.0 52.0 51.2 51.5 63.0 52.7 48.7 51.0 50.7 50.8 48.2 52.7 52.7 39.4 0.0 5.4 21.9 11.4 46.8 17.5 5.4 16.5 35.5 43.4 47.1 27.7 27.1 3.5 14.7 25.0 44.3 30.9 47.4 13.7 24.9 63.9 29.6 28.3 27.7 13.2 77.7 8.3 20.5 55.4 21.4 16.8 42.3 0.0 28.1 15.7 41.1 27.9 16.8 6.3 34.0 14.2 14.5 38.6 249.4 18.0 20.6 19.6 2.8 15.1 68.9 20.6 6.6 12.9 45.0 27.0 15.1 25.0 34.8 25.9 18.9 5.5 44.3 13.1 22.6 34.9 22.4 54.6 15.2 54.7 63.1 22.0 27.1 23.7 27.9 CDC6 CDC18L ENSG00000094804 "Cell division cycle 6" Q99741 17 40287879-40304657 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA replication, Mitosis" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 27.2;lymphoid tissue: 17.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 23.2;Erythroid cells: 37.2;Extravillous trophoblasts: 34.6;Plasma cells: 31.6;Spermatocytes: 69.5;Spermatogonia: 57.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 3.6" "Group enriched" "Detected in many" 6 "dendritic cells: 3.6;NK-cells: 1.5;T-cells: 2.4" "Cell line enhanced" "Detected in all" "SK-BR-3: 500.3" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA050114, HPA065070" Approved Approved "Nucleoplasm,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cytosol" "Cytokinetic bridge, Mitotic spindle" "HPA050114: AB_2681021, HPA065070: AB_2732729" "unprognostic (1.29e-1)" "unprognostic (7.22e-2)" "unprognostic (1.23e-3)" "unprognostic (7.97e-2)" "unprognostic (7.12e-2)" "unprognostic (2.89e-2)" "prognostic unfavorable (5.96e-8)" "unprognostic (2.31e-3)" "unprognostic (1.46e-3)" "unprognostic (1.41e-1)" "prognostic unfavorable (2.90e-4)" "unprognostic (5.47e-2)" "unprognostic (3.00e-15)" "unprognostic (1.86e-2)" "unprognostic (1.35e-1)" "unprognostic (3.95e-3)" "unprognostic (3.88e-2)" 2.1 1.9 0.5 13.7 0.8 27.2 3.4 0.2 1.9 3.2 0.0 8.4 7.5 2.2 1.1 5.7 1.0 2.8 0.6 1.1 0.1 0.5 3.0 1.4 16.4 0.1 0.0 0.9 1.9 0.8 0.5 9.3 0.3 1.1 8.7 0.5 1.3 1.2 0.3 2.8 6.7 3.7 0.0 3.7 3.6 10.1 0.2 16.7 1.7 0.5 17.1 4.3 1.8 0.6 155.1 119.0 115.1 86.5 6.7 12.7 118.0 159.9 49.0 149.2 166.5 135.8 64.9 123.9 99.6 35.9 85.9 214.0 112.2 76.2 148.9 64.5 98.4 96.2 122.3 134.6 4.4 133.3 55.1 4.7 8.1 156.4 107.1 14.8 46.9 84.2 183.0 109.0 71.9 95.8 199.3 43.3 101.6 96.9 48.7 145.0 286.8 119.9 30.3 184.8 85.6 76.9 146.9 500.3 55.4 100.3 100.8 120.0 34.7 95.5 146.3 170.8 196.1 46.1 103.6 222.8 84.6 93.9 109.2 0.1 0.1 0.0 0.8 0.0 0.5 0.4 0.6 1.1 0.7 0.3 0.4 1.1 0.1 1.5 0.0 3.6 2.4 0.6 0.5 0.8 0.2 1.9 1.1 0.1 0.1 0.0 0.3 0.0 0.2 0.6 2.2 0.0 2.0 0.7 4.9 4.2 1.1 3.7 3.4 0.2 2.1 2.2 0.9 1.5 1.3 0.0 0.0 23.2 2.3 7.8 0.0 1.3 2.2 1.3 2.9 2.1 0.0 37.2 2.0 0.6 34.6 5.6 3.6 5.1 0.0 8.1 1.1 0.9 8.3 0.0 0.7 6.1 0.0 1.3 2.1 1.0 2.8 1.5 0.0 0.0 0.0 0.4 2.1 0.0 0.2 1.5 3.0 0.7 31.6 1.3 0.8 0.2 0.2 0.3 13.1 0.6 4.6 69.5 57.2 9.1 1.6 16.7 3.3 1.9 9.3 2.4 CDCA5 ENSG00000146670 "Cell division cycle associated 5" Q96FF9 11 65066300-65084164 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 53.4;lymphoid tissue: 27.6;testis: 37.8" "Cell type enhanced" "Detected in many" "Early spermatids: 56.5;Extravillous trophoblasts: 38.3;Late spermatids: 116.9;Spermatocytes: 50.4;Spermatogonia: 31.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "NK-cell: 2.8;T-reg: 2.0" "Group enriched" "Detected in many" 5 "NK-cells: 2.8;T-cells: 2.0" "Low cell line specificity" "Detected in many" "Region enhanced" "Detected in single" "white matter: 1.4" "Low region specificity" "Detected in many" "HPA023691, HPA076007" Enhanced Enhanced Nucleoplasm Yes Yes "Cluster 15: NK-cells - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA023691: AB_1846392, HPA076007: " "unprognostic (3.14e-2)" "unprognostic (4.20e-2)" "unprognostic (1.05e-1)" "prognostic unfavorable (2.67e-4)" "unprognostic (2.15e-1)" "unprognostic (2.68e-1)" "prognostic unfavorable (8.21e-6)" "unprognostic (1.41e-3)" "unprognostic (7.55e-3)" "unprognostic (6.93e-2)" "prognostic unfavorable (8.72e-6)" "unprognostic (2.16e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.55e-3)" "unprognostic (1.86e-1)" "unprognostic (1.35e-1)" "unprognostic (8.97e-2)" 1.4 1.2 1.3 10.5 1.3 53.4 2.0 0.8 1.8 1.9 0.9 6.8 5.8 1.3 0.3 9.3 0.9 0.9 0.9 1.5 0.9 0.9 1.3 1.9 17.0 1.6 1.3 0.6 0.7 0.4 0.5 6.5 1.6 0.8 7.7 0.5 1.4 0.5 0.6 4.2 5.8 3.1 0.8 6.6 3.1 37.8 1.8 27.6 0.6 0.4 16.2 2.2 2.8 1.3 131.7 74.9 67.2 57.3 4.5 7.3 57.8 92.7 37.4 103.6 81.5 77.7 75.4 121.3 52.3 29.4 120.8 87.9 110.3 49.5 98.6 122.0 52.2 107.7 54.4 64.1 0.4 116.8 81.8 2.5 4.5 96.3 44.0 10.8 32.6 138.4 126.6 206.6 63.5 109.2 164.7 116.9 107.8 63.0 92.4 140.4 76.8 111.9 21.2 49.6 89.1 68.4 59.3 80.7 62.8 41.6 104.7 54.7 19.9 92.7 97.2 99.5 101.7 106.9 187.8 195.4 37.2 69.5 97.4 0.0 0.1 0.2 0.4 0.0 0.0 0.3 0.5 0.3 0.4 0.5 0.0 0.3 0.0 2.8 0.3 0.3 2.0 0.7 1.3 1.3 0.8 1.8 1.5 0.9 1.6 1.3 1.6 0.8 1.8 1.3 0.9 0.0 0.5 0.0 4.6 3.8 1.2 1.3 0.6 0.6 2.3 4.4 1.0 0.0 0.8 0.0 2.1 19.7 2.2 4.6 1.9 0.8 56.5 1.1 1.5 2.3 0.0 21.8 1.1 0.8 38.3 3.5 3.1 1.5 3.8 14.5 1.1 0.0 11.7 1.7 0.6 4.7 2.0 2.8 1.5 116.9 2.8 1.7 0.0 1.0 2.1 0.9 2.1 0.0 0.6 0.6 0.1 1.5 16.2 1.1 1.1 0.6 0.4 0.2 0.0 0.5 2.7 50.4 31.1 7.1 1.0 3.7 4.2 1.9 9.4 1.6 CDHR1 "CORD15, KIAA1775, PCDH21, RP65" ENSG00000148600 "Cadherin related family member 1" Q96JP9 10 84194537-84219621 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" Receptor "Cone-rod dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "retina: 313.8;skin 1: 214.0" "Group enriched" "Detected in many" 4 "Cone photoreceptor cells: 379.5;Rod photoreceptor cells: 240.4" "Cancer enhanced" "Detected in many" "colorectal cancer: 13.8" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 12 "NK-cell: 7.5" "Lineage enriched" "Detected in single" 12 "NK-cells: 7.5" "Cell line enhanced" "Detected in some" "HAP1: 10.2;HEK 293: 5.2;HEL: 6.3;K-562: 4.6;NTERA-2: 4.4;RPTEC TERT1: 16.3" "Region enriched" "Detected in many" 21 "olfactory bulb: 333.0" "Low region specificity" "Detected in all" HPA036819 Enhanced "Intracellular and membrane" NA NA 55000 "Cluster 15: NK-cells - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA036819: AB_10671750" "unprognostic (8.91e-4)" "unprognostic (5.60e-2)" "unprognostic (1.64e-1)" "unprognostic (2.71e-2)" "unprognostic (2.63e-2)" "unprognostic (3.03e-2)" "unprognostic (6.40e-2)" "unprognostic (7.77e-2)" "unprognostic (1.41e-1)" "unprognostic (2.67e-1)" "unprognostic (6.69e-4)" "unprognostic (1.90e-1)" "unprognostic (5.51e-3)" "unprognostic (1.26e-1)" "unprognostic (2.27e-1)" "unprognostic (4.56e-3)" "unprognostic (5.07e-2)" 0.2 1.9 7.4 1.0 18.3 0.4 4.5 2.3 8.7 5.3 46.2 29.2 0.1 0.6 4.4 10.7 0.5 0.4 1.2 6.6 7.5 0.4 0.5 0.2 0.9 13.4 2.3 1.1 0.1 0.0 3.0 0.2 13.9 1.4 53.2 313.8 1.5 4.2 1.0 214.0 12.2 1.2 0.1 7.0 0.2 0.3 3.2 3.3 0.2 0.0 1.1 0.1 3.5 3.5 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 10.2 2.0 0.0 0.0 5.2 6.3 0.0 0.0 0.2 0.0 0.2 0.0 2.2 0.0 0.7 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 1.5 4.4 0.0 0.0 0.0 0.0 1.4 16.3 0.0 3.4 0.8 0.0 0.0 0.0 2.5 0.0 0.2 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.1 7.4 18.3 2.3 8.7 6.6 7.5 13.4 2.3 13.9 0.1 3.2 3.5 0.0 0.0 0.5 1.3 0.1 51.2 0.3 1.4 3.4 24.1 0.0 0.1 1.8 0.0 0.7 0.0 379.5 0.0 2.1 47.9 0.0 0.1 0.0 2.7 0.7 1.8 12.7 0.0 4.9 0.0 0.0 0.6 0.0 3.1 0.0 3.7 0.4 0.4 0.0 5.0 7.7 46.9 0.0 0.3 5.2 0.2 0.0 0.1 3.6 1.0 0.0 26.3 1.0 7.5 4.4 0.0 31.2 0.0 0.7 0.3 23.0 0.2 0.1 240.4 0.0 0.2 0.3 0.6 0.3 3.0 67.5 0.0 3.0 0.3 52.9 0.2 CDKL2 "KKIAMRE, P56" ENSG00000138769 "Cyclin dependent kinase like 2" Q92772 4 75576496-75630716 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 8.3;choroid plexus: 8.6;retina: 9.6;testis: 11.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 76.4;Early spermatids: 57.8;Excitatory neurons: 32.8;Inhibitory neurons: 40.9;Oligodendrocytes: 46.4;Spermatocytes: 101.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 2.1;HHSteC: 1.9;RPTEC TERT1: 4.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040672 Approved Nucleoplasm,Centrosome NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Centrosome" "HPA040672: AB_10794744" "unprognostic (2.07e-1)" "unprognostic (9.96e-2)" "unprognostic (6.91e-2)" "unprognostic (3.80e-5)" "unprognostic (3.43e-2)" "unprognostic (2.71e-2)" "unprognostic (1.59e-1)" "unprognostic (8.14e-3)" "unprognostic (1.58e-1)" "unprognostic (1.62e-1)" "unprognostic (5.85e-2)" "unprognostic (1.27e-1)" "prognostic favorable (6.88e-15)" "unprognostic (5.91e-2)" "unprognostic (1.70e-1)" "unprognostic (1.64e-1)" "unprognostic (7.52e-2)" 0.1 1.0 6.3 0.3 6.7 0.0 0.3 4.1 8.3 0.6 8.6 0.7 0.1 0.6 0.9 0.8 1.6 0.4 0.3 6.5 6.1 5.9 0.0 4.7 0.3 6.0 4.8 1.6 0.5 2.5 1.5 0.0 6.5 0.6 0.9 9.6 0.3 0.6 0.0 0.2 0.1 0.4 4.9 0.1 0.6 11.6 5.8 0.0 3.1 0.0 0.6 0.2 0.3 8.3 2.1 0.3 0.1 0.0 0.1 0.1 0.0 0.1 0.8 1.0 0.9 0.1 0.5 0.0 0.3 0.0 1.0 0.2 0.0 0.2 0.9 0.1 1.5 0.0 0.1 0.0 1.9 0.0 0.0 0.6 1.0 0.1 0.3 0.9 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 4.2 0.1 1.1 0.9 0.0 0.0 0.5 1.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.7 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.3 6.7 4.1 8.3 6.5 6.1 6.0 4.8 6.5 4.9 5.8 8.3 0.2 25.6 76.4 5.9 0.4 0.1 0.5 0.6 0.6 17.7 0.7 3.0 0.9 1.5 4.7 9.2 4.2 0.1 0.3 3.0 7.9 1.9 57.8 11.6 1.4 0.2 1.8 0.0 32.8 0.2 0.6 1.2 1.1 2.5 1.3 1.0 0.4 0.0 0.1 10.1 40.9 2.3 0.0 0.0 0.4 20.7 1.8 0.5 1.8 3.7 0.0 11.6 0.0 5.5 46.4 0.1 1.0 1.2 0.3 0.2 0.0 29.5 18.6 20.2 0.0 0.4 1.1 101.7 4.1 0.8 0.3 0.3 2.7 0.2 2.7 0.2 CEACAM4 CGM7 ENSG00000105352 "CEA cell adhesion molecule 4" O75871 19 41618971-41627074 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 21.3;lymphoid tissue: 32.6" "Cell type enhanced" "Detected in some" "Kupffer cells: 41.1;Macrophages: 20.9;monocytes: 9.2" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 4 "neutrophil: 122.7" "Lineage enriched" "Detected in many" 4 "granulocytes: 122.7" "Cell line enriched" "Detected in single" 6 "U-937: 4.1" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "unprognostic (1.10e-2)" "unprognostic (1.52e-2)" "unprognostic (1.24e-1)" "unprognostic (4.48e-1)" "unprognostic (3.20e-2)" "unprognostic (3.83e-2)" "unprognostic (9.11e-2)" "unprognostic (5.59e-2)" "unprognostic (1.79e-2)" "unprognostic (1.97e-1)" "unprognostic (1.04e-1)" "unprognostic (2.17e-1)" "unprognostic (2.09e-9)" "unprognostic (3.65e-2)" "unprognostic (2.95e-2)" "unprognostic (1.47e-1)" "unprognostic (4.34e-1)" 2.1 0.5 0.1 4.8 0.1 21.3 0.5 0.1 0.2 0.4 0.2 0.7 0.3 0.3 0.8 1.0 1.0 1.0 0.8 0.1 0.1 0.8 1.0 5.7 0.9 0.2 0.2 0.2 1.2 0.0 0.3 0.3 0.2 1.1 0.2 0.0 0.8 0.0 0.2 0.3 1.8 1.0 0.1 32.6 0.8 0.1 0.2 0.3 0.4 0.6 0.6 0.7 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 30.1 5.6 0.0 23.1 0.1 0.7 1.2 0.0 23.3 0.0 0.7 0.0 122.7 0.0 9.9 0.2 11.3 12.1 0.1 0.1 0.1 0.2 0.1 0.1 0.2 0.2 0.2 0.1 0.2 0.2 0.1 0.0 3.9 0.0 0.9 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.1 3.1 0.0 0.0 0.0 0.0 41.1 1.6 0.2 0.0 20.9 1.8 1.9 9.2 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.1 0.0 CEACAM5 "CD66e, CEA" ENSG00000105388 "CEA cell adhesion molecule 5" P06731 19 41708585-41730433 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell adhesion" "Cancer-related genes, Oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "intestine: 981.2" "Group enriched" "Detected in some" 4 "Distal enterocytes: 1389.2;Intestinal goblet cells: 395.0;Paneth cells: 777.3" "Cancer enhanced" "Detected in many" "colorectal cancer: 1007.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "OE19: 56.9" "CAB000021, CAB000022, HPA011041, HPA019758" Enhanced Supported "Plasma membrane" "Intracellular and membrane" NA NA 23000000 "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "CAB000021: , CAB000022: AB_2335697, HPA011041: AB_1078481, HPA019758: AB_1846326" "unprognostic (1.54e-2)" "unprognostic (7.59e-2)" "unprognostic (5.49e-3)" "unprognostic (1.80e-1)" "unprognostic (1.38e-2)" "unprognostic (2.22e-1)" "unprognostic (3.49e-1)" "unprognostic (2.11e-1)" "unprognostic (2.19e-2)" "unprognostic (2.89e-1)" "unprognostic (8.67e-9)" "unprognostic (2.92e-1)" "unprognostic (2.71e-2)" "unprognostic (6.31e-2)" "unprognostic (1.85e-1)" 3.2 0.1 0.0 185.6 0.0 0.2 4.0 0.3 0.1 38.5 0.2 981.2 22.7 1.3 0.2 232.0 0.8 0.8 0.1 0.1 0.0 0.9 0.2 30.2 0.1 0.1 0.0 0.1 0.3 0.0 0.3 0.0 0.0 0.5 942.7 0.0 29.2 3.3 0.1 3.5 61.4 28.7 0.0 0.1 163.2 0.3 0.1 0.2 1.0 0.0 36.9 10.4 71.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.7 0.0 0.1 0.0 0.0 13.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.2 0.0 0.3 56.9 1.1 0.2 0.0 0.0 0.0 0.4 0.6 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.3 0.2 0.0 0.0 0.1 0.1 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 32.1 4.1 0.0 2.7 0.0 1.0 12.3 0.0 0.0 0.1 0.0 0.4 0.0 34.8 0.0 0.0 0.0 0.0 1389.2 0.0 3.4 0.4 0.0 0.0 0.2 65.7 0.0 0.1 0.9 0.0 0.4 22.4 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.1 395.0 4.1 0.0 0.4 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.1 21.3 777.3 0.0 0.1 16.5 10.2 0.0 4.5 0.0 0.0 0.1 0.4 0.8 0.5 1.9 0.0 0.0 1.2 0.0 192.3 124.4 CELF5 BRUNOL5 ENSG00000161082 "CUGBP Elav-like family member 5" Q8N6W0 19 3224661-3297076 "Predicted intracellular proteins" "mRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 21.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 93.1;Excitatory neurons: 88.7;Inhibitory neurons: 72.8;Oligodendrocyte precursor cells: 22.1" "Cancer enhanced" "Detected in some" "glioma: 2.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NTERA-2: 3.4;REH: 4.3;SCLC-21H: 4.3;SH-SY5Y: 2.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042012, HPA060336" Enhanced Supported NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 56: Bipolar cells - Visual perception" "HPA042012: AB_10796896, HPA060336: AB_2684256" "unprognostic (1.09e-1)" "unprognostic (9.24e-2)" "unprognostic (9.25e-3)" "unprognostic (3.48e-2)" "unprognostic (1.69e-1)" "unprognostic (5.44e-2)" "unprognostic (2.06e-1)" "unprognostic (1.17e-1)" "unprognostic (1.22e-3)" "unprognostic (1.35e-1)" "unprognostic (4.70e-3)" "unprognostic (1.11e-2)" "unprognostic (1.74e-3)" "unprognostic (1.23e-2)" "unprognostic (2.63e-2)" "unprognostic (1.25e-1)" "unprognostic (8.07e-2)" 0.0 0.2 13.5 0.0 15.1 0.0 0.5 0.0 21.9 0.0 0.0 0.2 0.0 0.3 0.2 0.0 0.5 0.0 0.0 15.7 14.4 0.1 0.2 0.0 0.0 0.0 0.0 4.1 0.5 1.3 0.9 0.0 0.0 0.2 0.1 4.4 0.8 0.1 0.3 0.1 0.1 0.0 0.0 0.0 0.3 2.1 6.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.9 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.2 0.0 0.0 0.6 0.0 0.0 3.4 1.4 0.0 4.3 0.0 0.0 0.0 0.0 4.3 2.6 0.2 0.2 0.0 0.1 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.5 15.1 0.0 21.9 15.7 14.4 0.0 0.0 0.0 0.0 6.4 0.0 0.1 0.0 0.0 3.3 0.2 0.4 2.1 0.0 0.0 93.1 3.9 6.6 2.2 2.8 0.0 0.0 0.0 0.4 0.2 1.6 0.0 0.6 19.3 0.2 0.2 0.4 1.2 0.0 88.7 0.2 0.1 0.4 0.0 0.6 0.0 12.1 0.0 0.8 0.1 8.4 72.8 1.4 0.0 0.3 0.3 15.5 0.3 0.3 0.0 8.4 0.0 3.4 0.0 22.1 3.2 0.4 0.1 2.2 0.0 2.3 0.1 0.4 0.0 3.7 0.0 1.1 0.8 2.5 7.7 0.0 0.3 0.0 0.3 1.4 1.6 0.9 CENPA "CenH3, CENP-A" ENSG00000115163 "Centromere protein A" P49450 2 26764289-26801067 "Predicted intracellular proteins" "Cell cycle, Cell division, Host-virus interaction, Mitosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 13.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 45.0;Extravillous trophoblasts: 33.2;Granulosa cells: 24.2;Plasma cells: 17.8;Spermatogonia: 28.6" "Cancer enhanced" "Detected in many" "testis cancer: 24.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB008371, HPA073086" Enhanced Supported Nucleoplasm NA Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB008371: AB_591074, HPA073086: AB_2686569" "unprognostic (3.94e-2)" "unprognostic (1.38e-1)" "unprognostic (2.29e-2)" "prognostic unfavorable (2.38e-4)" "unprognostic (1.13e-1)" "unprognostic (2.89e-2)" "prognostic unfavorable (2.88e-8)" "prognostic unfavorable (3.70e-4)" "unprognostic (1.69e-3)" "unprognostic (7.80e-2)" "prognostic unfavorable (1.30e-4)" "unprognostic (4.21e-3)" "unprognostic (0.00e+0)" "unprognostic (5.74e-2)" "unprognostic (1.33e-1)" "unprognostic (7.68e-2)" "unprognostic (2.07e-1)" 0.2 0.3 0.0 4.0 0.0 3.7 0.4 0.1 0.1 0.5 0.0 2.9 4.1 0.7 0.0 3.7 0.1 0.1 0.2 0.0 0.0 0.1 0.2 0.4 7.3 0.0 0.0 0.1 0.1 0.0 0.0 1.5 0.0 0.1 2.6 0.0 0.6 0.0 0.0 3.6 2.9 0.9 0.0 2.0 1.6 2.2 0.1 13.3 0.1 0.0 8.4 0.7 1.1 0.0 86.4 21.0 34.9 19.3 2.4 4.5 24.3 26.2 22.2 37.3 31.5 15.4 30.0 25.7 16.2 10.4 45.7 25.6 28.9 15.3 37.7 77.3 25.6 44.0 11.0 28.6 0.8 26.7 49.0 0.4 1.6 16.1 24.4 6.7 22.1 33.7 36.7 58.5 32.5 30.1 39.0 42.2 26.6 35.3 34.3 45.4 53.6 30.8 17.5 5.5 27.5 26.7 25.7 32.7 23.6 12.9 18.2 27.2 12.6 23.9 54.2 27.9 46.4 51.5 53.5 107.3 11.1 54.7 46.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 5.2 6.2 0.7 1.9 1.8 0.0 2.0 2.5 2.7 0.0 0.5 0.0 0.0 15.3 1.0 2.3 0.0 0.5 0.6 1.6 1.6 1.5 4.2 45.0 0.1 0.2 33.2 4.9 2.6 3.0 0.0 24.2 3.9 0.6 15.7 0.0 0.1 6.6 0.0 2.9 2.8 0.1 0.9 4.4 1.8 0.0 0.0 0.0 1.0 0.0 0.0 0.1 1.4 0.0 17.8 2.1 0.8 0.2 0.1 0.0 0.0 0.6 3.9 16.1 28.6 12.5 5.3 3.4 3.4 1.5 11.1 2.0 CENPI "CENP-I, FSHPRH1, LRPR1, Mis6" ENSG00000102384 "Centromere protein I" Q92674 X 101098218-101163681 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 6.8;lymphoid tissue: 7.1" "Cell type enhanced" "Detected in some" "Erythroid cells: 4.8;Excitatory neurons: 2.9;Extravillous trophoblasts: 4.7;Granulosa cells: 3.2;Oligodendrocytes: 3.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA061297 Supported "Nuclear bodies,Cytosol" NA Yes "Cluster 33: Neutrophils - Chromatin organization" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear bodies" Cytosol "HPA061297: AB_2684471" "unprognostic (3.10e-3)" "unprognostic (9.71e-2)" "unprognostic (1.86e-2)" "unprognostic (3.51e-3)" "unprognostic (1.24e-1)" "unprognostic (2.46e-2)" "unprognostic (5.78e-6)" "unprognostic (2.96e-2)" "unprognostic (7.71e-3)" "unprognostic (3.62e-3)" "unprognostic (1.20e-3)" "unprognostic (4.51e-2)" "unprognostic (2.50e-13)" "unprognostic (1.25e-2)" "unprognostic (1.47e-1)" "unprognostic (1.55e-1)" "unprognostic (1.42e-1)" 1.1 0.6 0.9 3.1 1.0 6.8 1.2 2.0 1.0 1.0 0.5 2.7 2.8 1.8 1.4 2.6 0.6 1.4 0.5 1.1 1.1 0.4 0.8 1.0 5.4 1.4 0.6 2.3 0.9 0.2 0.0 2.5 1.4 1.2 3.5 1.8 0.5 0.6 0.2 3.2 2.3 2.7 0.1 1.6 1.5 1.2 1.0 7.1 0.8 0.6 6.3 1.4 0.8 2.9 44.9 30.3 36.6 28.1 4.6 8.2 16.4 47.5 25.2 47.1 94.5 40.9 28.0 32.7 16.5 18.8 72.5 25.7 54.2 25.3 65.4 20.6 13.8 20.2 43.5 15.6 0.5 26.8 21.2 3.3 2.2 62.5 7.7 13.5 40.7 23.3 14.5 58.3 46.1 31.5 26.7 9.8 28.3 21.2 36.8 24.7 53.0 21.0 11.8 26.4 23.4 12.3 58.1 16.3 9.6 33.0 16.2 8.6 16.7 44.0 36.6 41.2 38.3 9.1 23.3 36.5 17.3 35.2 34.7 0.7 0.5 0.6 0.4 0.7 0.3 0.6 0.4 0.6 0.2 0.4 0.4 0.4 1.1 0.7 0.7 0.7 0.8 0.3 0.9 1.0 2.0 1.0 1.1 1.1 1.4 0.6 1.4 0.1 1.0 2.9 0.5 0.0 0.0 2.3 0.9 0.3 0.1 0.6 0.0 0.5 0.4 0.3 0.4 0.0 0.7 0.0 0.0 1.9 0.5 0.8 0.0 0.2 0.2 0.4 0.8 0.5 0.0 4.8 2.9 0.0 4.7 0.6 0.0 0.6 0.0 3.2 0.7 0.2 1.4 0.0 2.3 0.7 0.0 0.6 0.8 0.0 0.3 0.3 0.0 1.0 0.6 0.5 0.0 1.5 3.3 0.1 0.0 0.0 0.7 0.2 0.1 0.0 0.1 0.3 0.0 0.7 1.0 0.3 0.9 1.4 0.1 0.3 0.4 0.8 1.4 0.2 CENPP "CENP-P, RP11-19J3.3" ENSG00000188312 "Centromere protein P" Q6IPU0 9 92325953-92620529 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 21.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 63.3;Excitatory neurons: 73.4;Inhibitory neurons: 70.5;Microglial cells: 94.6;Oligodendrocytes: 74.5;Suprabasal keratinocytes: 100.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021787, HPA058945" Uncertain Supported Nucleoplasm,Nucleoli NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 28: Keratinocytes - Keratinization" Nucleoplasm Nucleoli "HPA021787: AB_1846524, HPA058945: AB_2683860" "unprognostic (5.48e-2)" "prognostic favorable (3.91e-4)" "unprognostic (1.20e-1)" "unprognostic (2.43e-3)" "unprognostic (2.64e-2)" "prognostic favorable (3.65e-4)" "unprognostic (4.88e-5)" "unprognostic (8.06e-2)" "unprognostic (3.51e-3)" "unprognostic (1.49e-1)" "unprognostic (1.32e-1)" "unprognostic (6.68e-3)" "unprognostic (9.20e-8)" "unprognostic (1.27e-2)" "unprognostic (5.12e-2)" "unprognostic (1.11e-1)" "unprognostic (2.04e-1)" 3.4 3.0 1.7 3.5 2.1 12.3 3.0 5.6 2.1 3.8 0.8 2.4 2.8 2.9 0.7 4.4 2.0 2.8 2.8 2.0 1.5 2.0 1.8 1.9 5.6 1.7 1.4 2.2 2.1 2.4 1.8 3.1 2.0 2.3 2.7 2.4 2.2 1.5 9.0 21.4 1.9 3.0 1.0 2.7 1.8 4.5 1.8 7.1 1.4 4.5 6.4 2.3 4.0 1.8 14.2 8.7 12.0 8.8 4.9 5.3 11.7 14.6 8.2 17.9 14.3 4.0 7.9 18.5 6.7 4.7 16.5 16.8 11.6 8.0 16.6 26.3 15.1 18.6 7.2 5.7 2.6 38.2 17.0 5.8 4.5 17.3 11.1 2.5 9.2 17.5 20.8 25.2 13.8 9.0 53.4 11.6 10.1 26.6 17.9 17.9 20.3 20.0 2.7 14.1 27.8 9.6 16.8 10.5 5.4 8.7 5.6 11.4 4.4 17.4 8.7 26.6 21.2 16.7 21.6 23.9 19.5 18.9 16.1 1.8 1.8 2.6 2.6 6.4 4.7 4.6 3.0 2.3 2.3 3.6 2.7 2.7 0.5 3.5 3.3 3.0 3.5 2.0 1.7 2.1 5.6 2.1 2.0 1.5 1.7 1.4 2.0 1.0 1.8 1.8 3.7 0.0 0.5 17.3 4.5 63.3 4.0 4.5 5.2 6.2 4.0 2.7 2.1 2.8 1.3 0.0 8.4 6.2 3.3 1.6 1.9 1.7 17.5 2.4 4.2 4.4 1.2 11.2 73.4 2.3 9.2 5.8 5.6 2.3 0.0 6.4 2.5 0.9 17.1 1.7 70.5 1.5 0.0 2.1 11.7 4.7 4.4 4.0 14.2 94.6 0.5 2.8 1.0 38.2 74.5 1.1 0.4 4.9 11.9 2.8 0.4 1.8 0.3 7.8 6.6 20.8 9.2 30.2 16.2 9.8 100.9 3.8 3.6 4.4 2.6 2.7 CES1 "CEH, CES1A1, CES1A2, CES2, HMSE, HMSE1, SES1" ENSG00000198848 "Carboxylesterase 1" P23141 16 55802851-55833337 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "liver: 2517.1" "Group enriched" "Detected in many" 7 "Cholangiocytes: 613.4;Hepatocytes: 2420.8" "Cancer enriched" "Detected in all" 6 "liver cancer: 711.4" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 16 "classical monocyte: 109.6;myeloid DC: 114.5" "Group enriched" "Detected in many" 22 "dendritic cells: 114.5;monocytes: 109.6" "Group enriched" "Detected in some" 5 "Hep G2: 700.9;THP-1: 688.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA012023, HPA046717" Enhanced Supported "Endoplasmic reticulum" "Intracellular and membrane" No NA 40000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Endoplasmic reticulum" "HPA012023: AB_1846554, HPA046717: AB_2679770" "unprognostic (1.04e-2)" "unprognostic (9.85e-2)" "unprognostic (2.94e-1)" "unprognostic (1.28e-1)" "unprognostic (1.55e-3)" "unprognostic (7.46e-3)" "unprognostic (1.51e-1)" "unprognostic (1.42e-1)" "unprognostic (3.51e-1)" "unprognostic (5.74e-2)" "unprognostic (4.62e-2)" "unprognostic (3.29e-2)" "unprognostic (1.91e-2)" "unprognostic (5.32e-2)" "unprognostic (1.92e-1)" "unprognostic (2.87e-1)" "prognostic unfavorable (9.92e-4)" 94.9 14.1 0.9 3.2 1.2 27.0 43.6 0.8 1.8 26.6 3.7 82.3 24.0 60.4 7.5 41.1 54.6 272.9 66.1 1.0 1.4 6.7 2517.1 167.8 1.8 2.3 1.2 20.3 8.8 0.7 3.7 8.5 1.5 39.2 12.3 2.9 41.4 36.4 5.2 14.0 27.4 40.4 1.0 41.0 56.1 7.8 1.1 2.5 9.9 9.4 1.0 57.7 17.7 1.1 0.7 4.4 0.0 0.0 90.8 0.6 3.1 0.3 0.0 0.0 0.0 43.5 0.0 0.0 19.4 0.0 1.4 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.9 700.9 0.0 1.3 0.1 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 40.8 0.1 0.6 0.0 0.0 1.5 6.7 0.0 0.5 0.0 0.1 3.2 0.1 1.1 0.9 0.0 688.0 0.1 0.0 0.4 0.2 0.5 2.2 0.1 1.0 0.0 151.7 0.0 0.0 109.6 0.5 4.5 6.1 1.5 1.1 0.7 5.0 114.5 1.2 0.7 1.1 0.6 0.3 1.6 6.8 0.4 58.0 0.9 1.2 0.8 1.8 1.0 1.4 2.3 1.2 1.5 1.0 1.1 1.1 2.0 16.0 67.6 0.0 11.3 16.7 5.3 6.8 1.2 0.0 1.2 8.1 0.8 613.4 31.5 16.5 0.0 0.5 12.2 0.1 0.0 15.4 79.6 1.0 10.6 8.9 37.5 177.7 0.0 18.7 2.2 57.4 1.1 0.2 6.3 0.0 66.0 2420.8 18.1 0.0 0.0 12.2 4.1 107.3 26.7 197.8 18.6 58.7 39.2 1.0 39.6 10.4 7.2 0.0 0.0 0.9 1.3 98.9 1.8 1.5 0.6 0.9 169.0 0.9 0.0 9.8 9.8 1.0 2.3 20.6 11.6 0.8 16.9 0.9 0.7 2.6 CES4A "CES8, FLJ37464" ENSG00000172824 "Carboxylesterase 4A" Q5XG92 16 66988589-67009758 "Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 16.9;skin 1: 13.6" "Cell type enhanced" "Detected in many" "Breast glandular cells: 44.4;Excitatory neurons: 53.6;Oligodendrocytes: 37.6;Respiratory ciliated cells: 47.1" "Cancer enhanced" "Detected in many" "renal cancer: 5.3" "Region enhanced" "Detected in many" "white matter: 10.2" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 3.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HDLM-2: 19.1;HMC-1: 5.2;PC-3: 4.5;SiHa: 7.8;SK-BR-3: 5.7;U-266/70: 5.9" "Not detected" "Not detected" HPA035701 Approved Approved Cytosol "Secreted - unknown location" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 31: Skin - Epidermis development" "Cluster 44: HDLM-2 - Immune response" "Cluster 30: Mammary glandular cells - Lactation" Cytosol "HPA035701: AB_10696357" "unprognostic (6.34e-2)" "unprognostic (2.09e-1)" "unprognostic (3.18e-1)" "unprognostic (3.26e-2)" "unprognostic (1.99e-1)" "unprognostic (6.20e-2)" "unprognostic (2.12e-2)" "unprognostic (2.04e-2)" "unprognostic (5.78e-3)" "unprognostic (3.93e-2)" "unprognostic (2.02e-3)" "unprognostic (3.15e-2)" "prognostic unfavorable (2.35e-6)" "unprognostic (1.20e-1)" "unprognostic (2.23e-1)" "unprognostic (1.74e-2)" "unprognostic (1.33e-3)" 3.6 1.5 1.2 0.8 2.6 1.2 2.5 0.1 2.5 1.0 0.0 0.6 0.8 0.5 3.9 1.0 16.9 0.8 2.4 2.3 1.0 2.6 8.4 1.5 0.7 1.7 0.2 1.0 1.1 3.1 3.6 1.0 1.2 0.9 0.7 0.8 4.3 2.1 4.9 13.6 0.8 0.3 0.0 0.5 1.4 0.8 0.8 0.7 2.7 0.2 0.9 1.2 0.7 10.2 0.2 1.5 0.1 0.0 0.9 0.8 0.0 0.4 0.7 0.1 0.0 0.0 2.3 0.0 0.0 1.5 0.0 0.7 0.0 0.2 0.0 19.1 0.0 0.0 1.2 0.0 0.1 0.0 5.2 1.8 3.5 0.2 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.8 4.5 0.2 0.0 1.1 0.0 0.3 1.4 0.9 7.8 5.7 0.0 0.1 0.0 0.3 0.3 0.0 0.0 0.0 0.0 5.9 2.2 0.0 1.4 0.0 0.0 0.0 1.4 0.0 0.5 2.5 0.5 0.6 1.0 0.5 0.8 0.0 0.9 0.2 0.0 0.0 3.5 1.2 0.3 0.7 1.2 2.6 0.1 2.5 2.3 1.0 1.7 0.2 1.2 0.0 0.8 10.2 0.4 0.0 11.4 2.0 3.5 5.4 5.7 5.0 3.4 23.1 44.4 7.7 2.8 4.3 7.3 5.5 14.6 4.7 3.9 4.1 1.9 0.9 1.7 9.9 1.4 1.0 9.0 0.0 53.6 1.6 0.9 3.9 3.1 11.1 9.5 4.9 1.1 22.1 5.6 0.0 29.7 1.8 4.1 4.1 2.1 1.2 13.7 3.2 0.0 4.7 5.7 8.3 4.1 6.6 37.6 0.9 9.7 12.8 1.3 3.5 5.8 1.5 47.1 15.3 0.0 1.5 1.8 32.1 11.8 4.1 5.3 4.5 3.3 13.5 3.5 7.5 CFI "C3b-INA, FI, IF, KAF" ENSG00000205403 "Complement factor I" P05156 4 109740694-109801999 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Complement pathway, Host-virus interaction, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease variant, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 1098.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 108.7;Hepatocytes: 592.5;Muller glia cells: 147.8;Proximal tubular cells: 223.6" "Cancer enhanced" "Detected in all" "liver cancer: 90.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 106.1;Hep G2: 179.8;HSkMC: 67.4;RPTEC TERT1: 190.6" "HPA001143, CAB016777, HPA024061" Supported "Secreted to blood" NA NA 12000000000 "Cluster 85: Liver - Metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB016777: , HPA001143: AB_1078555, HPA024061: AB_1847129" "unprognostic (1.04e-1)" "unprognostic (5.79e-2)" "unprognostic (1.68e-1)" "unprognostic (6.32e-2)" "unprognostic (1.55e-2)" "unprognostic (8.58e-2)" "unprognostic (2.95e-2)" "unprognostic (3.00e-1)" "unprognostic (2.00e-2)" "unprognostic (5.42e-3)" "unprognostic (1.41e-1)" "unprognostic (3.61e-1)" "unprognostic (8.63e-2)" "unprognostic (1.29e-1)" "unprognostic (3.42e-2)" "unprognostic (1.74e-1)" "prognostic unfavorable (6.06e-4)" 45.1 50.2 8.1 12.6 8.2 0.1 17.4 7.7 13.2 36.8 10.4 7.4 38.0 39.2 80.3 9.3 74.0 73.0 25.0 8.3 9.6 224.9 1098.8 50.7 8.9 15.6 10.2 32.1 26.0 3.1 8.4 24.1 10.7 8.3 6.4 53.0 15.0 26.7 3.9 2.7 22.3 24.3 10.5 33.1 14.4 8.8 9.2 2.3 14.5 4.6 7.5 34.1 8.3 10.6 0.0 0.6 0.0 0.3 0.0 0.2 0.1 1.5 1.4 0.1 0.2 0.0 106.1 0.0 32.9 0.0 0.5 0.0 0.0 0.0 0.0 34.8 0.7 0.0 0.4 179.8 6.2 0.3 0.0 67.4 0.0 0.1 0.0 3.6 4.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 190.6 0.5 0.0 0.3 1.6 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.4 0.6 0.0 0.0 0.0 0.1 18.8 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 8.2 7.7 13.2 8.3 9.6 15.6 10.2 10.7 10.5 9.2 10.6 48.1 12.8 50.9 3.6 4.0 1.0 12.2 15.2 0.6 3.4 2.1 5.6 2.3 108.7 36.2 64.4 2.1 0.1 0.3 1.7 31.3 69.3 0.2 34.1 46.4 57.7 0.0 2.7 0.3 30.9 0.2 34.3 8.2 33.6 3.8 72.1 55.0 592.5 0.7 1.7 0.2 1.9 0.0 16.7 1.5 0.8 16.8 2.0 0.0 4.7 1.6 147.8 0.0 0.0 0.3 30.8 2.4 0.0 0.0 3.8 17.0 223.6 8.4 7.3 0.0 1.3 9.4 1.6 0.5 1.9 1.1 0.3 3.4 18.5 4.1 12.6 CGN KIAA1319 ENSG00000143375 Cingulin Q9P2M7 1 151510510-151538692 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 56.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 118.6;Distal enterocytes: 173.2;Paneth cells: 108.7;Proximal enterocytes: 88.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 91.4;CAPAN-2: 59.1;OE19: 58.6;RT4: 44.0" "Low region specificity" "Detected in many" "CAB017193, HPA027586, HPA027587, HPA027657" Enhanced Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cell Junctions" "CAB017193: , HPA027586: AB_10600208, HPA027587: AB_10601884, HPA027657: AB_10611527" "unprognostic (1.57e-1)" "unprognostic (4.30e-2)" "unprognostic (1.12e-1)" "unprognostic (8.74e-3)" "unprognostic (1.02e-1)" "unprognostic (3.01e-1)" "unprognostic (1.98e-1)" "unprognostic (8.38e-2)" "unprognostic (4.61e-1)" "unprognostic (2.11e-2)" "unprognostic (2.96e-3)" "unprognostic (7.10e-2)" "prognostic favorable (5.84e-10)" "unprognostic (2.66e-1)" "unprognostic (3.00e-1)" "unprognostic (8.28e-2)" "unprognostic (2.10e-2)" 5.8 1.1 1.9 6.0 3.3 0.4 9.0 8.5 3.3 4.9 6.5 37.2 52.7 1.4 1.5 8.6 13.2 13.6 0.6 2.0 3.7 12.2 32.1 27.3 0.4 5.5 3.0 2.0 24.2 32.1 3.7 1.6 5.6 10.1 25.1 3.7 21.1 7.0 0.2 17.9 56.4 1.5 1.7 0.4 30.4 6.6 3.4 0.7 4.9 0.1 2.3 8.3 6.2 6.7 28.9 3.2 2.7 4.6 0.0 0.0 35.4 0.1 0.1 0.8 0.9 91.4 59.1 1.3 9.4 0.0 4.9 27.0 8.6 5.0 0.6 17.3 6.0 2.4 1.3 1.8 0.0 0.4 3.6 0.0 1.0 1.3 0.7 0.0 0.3 7.8 1.2 8.1 0.0 26.8 5.0 0.6 22.9 58.6 2.5 5.4 2.8 4.3 17.9 44.0 8.9 4.4 1.8 27.1 1.0 10.3 33.5 0.3 0.5 0.3 8.3 0.5 1.2 7.7 8.4 5.2 0.3 3.3 2.4 0.2 0.1 0.0 0.5 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.4 0.2 0.1 0.1 0.1 0.0 1.9 3.3 8.5 3.3 2.0 3.7 5.5 3.0 5.6 1.7 3.4 6.7 0.1 118.6 33.3 2.3 0.2 0.3 3.3 5.9 0.6 4.3 14.9 9.1 0.7 24.3 22.4 3.7 0.0 3.5 0.5 173.2 0.0 21.5 0.3 13.8 2.1 0.6 10.3 2.7 0.8 25.4 0.3 2.3 54.6 27.3 0.0 0.5 0.0 29.6 0.3 0.0 10.4 32.7 8.2 0.0 0.4 1.2 0.6 0.5 3.6 0.0 2.1 13.5 0.0 3.5 11.7 49.5 108.7 0.7 0.5 11.9 88.7 3.0 46.8 1.5 0.0 0.1 1.0 1.5 6.9 4.2 1.8 0.4 0.6 1.8 27.2 18.3 CHAC1 MGC4504 ENSG00000128965 "ChaC glutathione specific gamma-glutamylcyclotransferase 1" Q9BUX1 15 40952962-40956512 "Enzymes, Predicted intracellular proteins" "Apoptosis, Neurogenesis, Notch signaling pathway, Unfolded protein response" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 68.6;skeletal muscle: 68.4" "Cell type enhanced" "Detected in many" "Distal tubular cells: 35.2;Exocrine glandular cells: 27.8;Gastric mucus-secreting cells: 33.6;Pancreatic endocrine cells: 19.3;Plasma cells: 21.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 109.5;HHSteC: 80.7;hTCEpi: 130.8;SK-MEL-30: 95.0;U-266/70: 81.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA042708, HPA043505" Approved Approved Mitochondria NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 1: Pancreatic cells - Digestion" Mitochondria "HPA042708: AB_2678125, HPA043505: AB_2678518" "unprognostic (6.04e-3)" "unprognostic (2.81e-2)" "unprognostic (7.47e-2)" "unprognostic (2.84e-3)" "unprognostic (6.57e-3)" "unprognostic (2.00e-2)" "unprognostic (5.59e-2)" "unprognostic (2.43e-1)" "unprognostic (2.01e-1)" "unprognostic (1.72e-1)" "unprognostic (3.11e-1)" "unprognostic (1.51e-1)" "prognostic unfavorable (2.23e-7)" "unprognostic (1.37e-2)" "unprognostic (1.44e-1)" "unprognostic (1.67e-2)" "unprognostic (3.91e-2)" 9.1 0.6 12.3 1.4 12.0 1.8 0.9 11.1 30.7 2.1 7.1 1.9 2.0 0.7 1.5 23.3 1.7 1.8 2.4 11.4 16.6 4.0 11.5 2.0 0.9 13.0 14.5 0.7 68.6 1.4 1.9 0.8 16.9 1.3 0.8 1.1 5.1 1.0 68.4 1.6 1.4 0.8 12.6 0.9 14.8 0.7 17.6 0.5 1.5 11.7 3.0 4.3 3.7 16.6 9.1 6.0 1.5 27.2 4.3 3.2 11.1 53.5 109.5 5.8 15.5 15.1 2.2 2.8 4.1 4.8 17.2 6.0 12.0 4.4 4.1 10.4 2.5 2.5 1.6 0.0 80.7 7.3 0.1 36.1 130.8 17.1 23.2 1.8 5.4 62.3 7.7 12.5 4.8 5.5 5.3 0.1 4.9 31.0 21.3 4.8 0.1 12.8 3.0 3.5 5.3 7.9 1.6 9.5 95.0 3.3 3.6 51.1 1.8 1.3 16.1 1.5 9.4 81.1 19.0 11.0 4.8 10.3 12.7 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 12.3 12.0 11.1 30.7 11.4 16.6 13.0 14.5 16.9 12.6 17.6 16.6 6.2 0.0 2.0 0.3 3.1 2.8 3.8 11.5 3.4 2.6 2.2 2.4 4.6 4.3 6.5 0.0 2.1 0.3 2.6 8.0 35.2 6.4 0.1 1.8 0.4 2.7 3.5 3.2 1.3 27.8 0.3 0.6 33.6 2.1 0.0 0.4 1.8 0.7 0.4 0.0 1.5 8.0 6.1 0.3 1.5 0.0 0.3 0.8 5.4 0.0 1.0 0.5 0.0 0.5 0.2 19.3 2.3 0.0 21.4 6.5 0.8 0.3 3.3 0.4 0.0 0.3 3.2 1.1 1.1 1.5 4.3 3.4 1.6 0.5 4.8 14.6 CHDH ENSG00000016391 "Choline dehydrogenase" Q8NE62 3 53812335-53846419 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 37.6;liver: 35.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 52.9;Hepatocytes: 51.8;Proximal enterocytes: 70.1;Proximal tubular cells: 87.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 11 "basophil: 3.1;T-reg: 1.3" "Group enriched" "Detected in many" 17 "granulocytes: 3.1;T-cells: 1.3" "Cell line enhanced" "Detected in many" "CACO-2: 11.4;Hep G2: 35.8;OE19: 25.3;T-47d: 11.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA036633, HPA058130" Enhanced NA NA "Cluster 10: Basophils - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA036633: AB_10670841, HPA058130: AB_2683615" "unprognostic (3.40e-3)" "unprognostic (1.17e-2)" "unprognostic (2.26e-3)" "unprognostic (7.17e-3)" "unprognostic (9.15e-2)" "unprognostic (1.17e-3)" "unprognostic (1.10e-1)" "unprognostic (1.97e-2)" "unprognostic (2.75e-1)" "unprognostic (4.35e-3)" "unprognostic (4.57e-2)" "unprognostic (5.12e-2)" "prognostic favorable (1.88e-8)" "unprognostic (3.37e-2)" "unprognostic (2.42e-1)" "unprognostic (8.26e-2)" "unprognostic (2.29e-2)" 0.6 2.8 13.6 1.8 14.3 0.6 7.3 12.5 11.4 3.7 16.5 8.9 8.4 2.7 1.4 0.9 2.6 2.7 2.4 11.3 10.9 37.6 35.8 2.4 1.0 14.5 13.9 1.3 16.4 8.3 7.8 0.4 10.1 5.8 9.2 1.5 15.0 1.0 3.9 2.4 14.7 0.9 10.3 0.5 8.0 6.9 15.9 0.2 2.6 1.2 1.2 0.4 0.9 12.0 0.4 4.6 1.2 0.1 0.0 0.0 5.2 0.3 0.5 0.0 0.0 11.4 0.8 0.4 0.8 0.8 0.1 0.0 7.4 0.0 0.0 0.0 4.0 0.0 1.7 35.8 0.0 0.1 0.7 0.1 0.0 0.0 0.0 0.6 0.0 0.0 5.7 0.7 0.0 6.9 0.0 0.1 7.2 25.3 0.8 0.0 1.8 8.2 5.1 4.0 3.0 4.0 1.8 0.1 0.0 0.9 11.2 0.1 0.0 0.0 0.8 0.2 1.0 1.0 1.6 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.3 0.0 13.6 14.3 12.5 11.4 11.3 10.9 14.5 13.9 10.1 10.3 15.9 12.0 0.6 3.2 6.8 19.6 1.3 6.6 5.6 1.1 1.2 23.8 23.5 19.8 11.3 52.9 5.9 11.0 14.6 3.7 0.4 16.6 7.9 19.4 28.9 3.2 11.0 1.4 47.9 0.0 2.4 13.8 2.3 2.3 21.4 9.4 7.0 2.2 1.4 51.8 0.3 1.7 3.5 38.9 0.0 1.9 2.5 46.2 5.9 2.6 3.6 1.0 0.1 18.8 0.0 27.2 5.2 8.0 15.1 15.4 5.3 19.8 70.1 87.8 3.8 13.4 0.0 1.0 3.4 15.1 2.3 0.7 5.3 0.8 2.4 2.0 45.4 2.2 CHEK1 CHK1 ENSG00000149554 "Checkpoint kinase 1" O14757 11 125625665-125676255 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 25.7;lymphoid tissue: 20.7;seminal vesicle: 29.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 32.9;Erythroid cells: 34.5;Extravillous trophoblasts: 35.6;Spermatocytes: 48.9;Spermatogonia: 49.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "T-reg: 6.2" "Group enriched" "Detected in many" 5 "granulocytes: 1.7;T-cells: 6.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA044364 Supported Nucleoplasm,Vesicles NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Vesicles "HPA044364: AB_2678913" "unprognostic (6.74e-2)" "unprognostic (3.63e-1)" "prognostic favorable (3.62e-4)" "unprognostic (5.54e-2)" "unprognostic (2.17e-1)" "unprognostic (1.03e-1)" "prognostic unfavorable (3.70e-6)" "unprognostic (3.95e-3)" "unprognostic (1.26e-3)" "unprognostic (2.54e-2)" "prognostic unfavorable (3.10e-6)" "unprognostic (1.75e-1)" "prognostic unfavorable (1.04e-8)" "unprognostic (2.89e-2)" "unprognostic (2.64e-1)" "unprognostic (8.16e-2)" "unprognostic (1.33e-1)" 1.6 1.3 0.7 8.2 1.0 25.7 2.6 0.6 1.3 1.7 0.5 7.9 6.8 1.7 6.7 4.1 1.1 1.7 0.9 0.7 0.9 2.2 2.1 1.3 14.9 0.7 0.8 1.8 2.0 13.2 1.7 4.8 0.8 1.6 8.7 0.7 1.5 29.8 0.6 3.6 7.3 3.4 0.6 2.2 2.6 8.9 1.2 20.7 1.0 1.3 13.9 3.3 2.1 0.8 48.5 37.0 81.1 47.4 13.5 28.9 35.7 61.1 28.7 41.6 40.1 88.0 100.3 120.7 63.5 24.9 53.7 52.6 54.2 33.2 50.1 81.4 24.8 224.2 27.2 44.7 4.3 121.1 39.6 15.7 6.0 47.6 36.0 19.9 44.7 84.1 117.3 102.7 51.4 23.8 181.3 65.0 86.1 77.1 33.2 104.7 74.4 67.2 37.9 63.2 50.5 53.6 45.2 35.4 15.2 57.3 93.9 40.6 28.4 51.0 47.3 29.6 60.8 21.9 45.4 187.5 20.5 86.6 67.6 1.7 0.2 0.0 0.4 0.1 0.2 0.7 1.6 0.4 0.6 0.3 0.4 0.3 1.1 0.3 0.1 0.7 6.2 0.4 0.7 1.0 0.6 1.3 0.7 0.9 0.7 0.8 0.8 0.6 1.2 0.8 1.1 3.2 0.5 1.6 5.5 6.2 3.9 5.8 5.2 1.7 3.9 6.0 4.6 32.9 4.1 7.3 0.0 17.3 6.0 4.5 3.9 3.4 7.8 5.5 8.0 3.5 1.8 34.5 3.3 1.1 35.6 5.3 6.1 9.9 0.0 21.1 3.6 1.2 11.1 0.0 2.5 9.2 2.0 0.0 5.2 3.1 1.5 3.2 0.0 2.8 3.2 2.8 3.1 1.5 1.6 2.9 3.9 1.2 17.7 3.1 8.0 9.4 2.5 1.7 0.0 3.1 7.8 48.9 49.8 9.5 4.8 7.8 5.1 4.8 16.7 3.0 CHEK2 "bA444G7, CDS1, CHK2, HuCds1, PP1425, RAD53" ENSG00000183765 "Checkpoint kinase 2" O96017 22 28687743-28742422 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell cycle, Cell division, DNA damage, DNA repair, Mitosis, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Li-Fraumeni syndrome, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Spermatogonia: 31.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA001878, CAB002030" Enhanced Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Golgi apparatus" "CAB002030: AB_563660, HPA001878: AB_1078514" "unprognostic (1.54e-1)" "unprognostic (2.20e-1)" "unprognostic (5.83e-2)" "unprognostic (2.93e-2)" "unprognostic (2.42e-1)" "unprognostic (3.83e-2)" "unprognostic (1.49e-3)" "unprognostic (5.08e-3)" "unprognostic (3.33e-3)" "unprognostic (9.62e-3)" "unprognostic (1.28e-2)" "unprognostic (3.13e-1)" "prognostic unfavorable (7.80e-9)" "unprognostic (2.38e-2)" "unprognostic (1.78e-1)" "unprognostic (7.27e-2)" "unprognostic (6.79e-3)" 4.5 6.2 2.4 8.8 2.5 15.4 5.8 2.4 3.7 5.0 2.8 8.8 6.3 4.1 7.3 7.2 3.7 4.7 4.2 2.3 2.8 4.5 6.3 4.4 12.1 2.6 2.6 8.2 2.3 1.3 2.7 7.8 2.8 4.1 10.9 0.4 3.2 3.8 1.3 6.7 7.0 4.8 2.6 6.7 4.1 8.5 2.8 9.4 3.3 1.1 12.0 6.8 5.0 2.9 30.7 9.7 31.1 32.4 10.1 42.7 18.7 15.2 19.9 18.7 27.8 29.1 21.8 36.3 13.0 11.5 21.6 32.1 42.7 29.0 25.0 24.6 31.2 45.3 25.5 46.2 9.4 33.4 38.0 18.6 13.5 25.0 23.0 14.1 25.4 29.4 30.5 33.9 19.8 39.2 24.6 61.5 40.6 41.3 21.6 52.6 18.2 42.7 17.1 11.2 17.8 9.7 16.7 31.4 17.4 22.8 22.6 32.2 7.8 17.1 19.4 14.3 9.1 21.8 28.3 65.4 17.1 34.9 21.0 9.9 4.0 1.2 1.1 8.1 2.4 11.9 2.1 2.1 8.2 7.8 4.0 2.6 0.6 3.4 4.1 6.1 2.8 3.6 2.4 2.5 2.4 3.7 2.3 2.8 2.6 2.6 2.8 2.6 2.8 2.9 2.3 9.6 4.8 2.9 5.5 6.4 5.3 8.3 8.6 1.1 3.2 3.9 1.8 0.0 5.0 1.8 0.0 15.4 1.1 3.8 0.0 1.8 7.0 2.9 10.1 3.0 1.2 11.2 2.9 1.4 13.6 12.4 5.1 7.0 3.8 7.4 2.5 1.3 9.7 0.0 1.2 5.3 8.2 2.4 8.5 1.2 6.2 5.1 1.8 2.8 3.9 0.8 6.2 0.0 1.0 1.0 4.7 4.5 11.4 2.7 3.0 3.9 2.9 1.1 0.0 10.2 3.0 6.7 31.2 8.3 2.3 3.4 3.3 5.7 10.0 4.5 CHMP4A "C14orf123, HSPC134, VPS32A" ENSG00000254505 "Charged multivesicular body protein 4A" Q9BY43 14 24209615-24213830 "Metabolic proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068473 Approved NA NA 1400000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 63: NK-cells & T-cells - Immune response" "HPA068473: AB_2685994" "unprognostic (4.33e-3)" "unprognostic (3.76e-2)" "unprognostic (4.29e-2)" "unprognostic (5.45e-2)" "unprognostic (4.29e-1)" "unprognostic (1.25e-1)" "unprognostic (1.74e-4)" "unprognostic (2.02e-3)" "unprognostic (9.61e-2)" "unprognostic (1.76e-2)" "unprognostic (1.44e-2)" "unprognostic (1.57e-1)" "prognostic unfavorable (3.91e-8)" "unprognostic (3.30e-1)" "unprognostic (3.42e-1)" "unprognostic (7.37e-2)" "unprognostic (6.90e-2)" 58.8 39.5 73.9 49.3 77.3 38.5 51.4 74.2 109.3 39.1 68.5 59.2 39.4 33.6 79.0 50.5 45.2 35.8 46.9 71.2 73.4 52.4 53.5 36.1 72.6 76.6 75.6 30.8 42.5 72.9 23.0 33.9 76.5 51.0 64.5 15.5 31.5 60.6 20.1 51.6 43.6 51.6 76.8 51.5 45.8 16.5 78.1 70.4 43.4 27.4 84.9 47.7 32.0 77.7 48.7 100.5 43.8 49.1 75.4 67.9 59.7 52.9 62.6 53.0 60.7 46.6 114.9 79.0 48.5 80.6 49.8 56.4 47.5 84.7 58.8 142.6 25.6 64.7 91.6 207.4 131.8 101.1 69.9 69.1 121.6 43.9 168.4 60.8 72.3 84.6 68.2 119.7 107.1 136.1 98.0 93.5 29.0 123.3 83.0 71.9 37.5 86.7 99.3 128.4 28.4 34.3 112.7 101.8 73.8 49.8 65.7 90.2 49.4 33.0 40.0 42.7 47.2 117.1 133.2 86.4 31.2 71.7 71.3 144.3 152.2 103.4 123.4 195.6 132.9 182.8 131.8 138.5 179.9 169.3 101.6 109.9 42.6 138.4 193.6 190.0 185.2 171.6 73.9 77.3 74.2 109.3 71.2 73.4 76.6 75.6 76.5 76.8 78.1 77.7 74.2 16.0 33.3 13.4 78.6 52.6 76.0 154.8 18.8 31.8 66.7 65.7 2.1 92.9 86.3 62.5 64.6 93.4 111.4 50.0 97.8 116.0 11.0 49.1 52.5 58.8 39.2 53.7 14.3 82.3 84.0 39.3 25.5 53.2 76.5 41.1 67.5 73.1 162.5 25.2 12.6 69.9 99.7 94.8 90.3 19.1 66.8 80.1 69.4 11.2 202.6 64.7 178.2 12.1 15.5 76.0 66.7 48.5 44.8 76.1 144.9 159.3 72.2 24.2 98.6 40.6 58.1 20.4 18.3 32.3 78.8 120.7 102.8 43.8 79.7 70.4 CHP2 ENSG00000166869 "Calcineurin like EF-hand protein 2" O43745 16 23755026-23758935 "Cancer-related genes, Predicted intracellular proteins" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 16 "intestine: 305.0;skin 1: 149.7" "Group enriched" "Detected in some" 5 "Distal enterocytes: 345.0;Paneth cells: 274.0;Proximal enterocytes: 654.2;Undifferentiated cells: 205.4" "Cancer enhanced" "Detected in many" "colorectal cancer: 10.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-HME1: 7.3;hTERT-RPE1: 10.2;NB-4: 8.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA055198, CAB072806" Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 24: NB-4 - Immune response" "Cluster 45: Enterocytes - Digestion" Nucleoplasm "Nucleoli, Cytosol" "CAB072806: , HPA055198: " "unprognostic (4.82e-1)" "unprognostic (3.40e-1)" "unprognostic (4.93e-2)" "unprognostic (1.01e-2)" "unprognostic (8.85e-2)" "unprognostic (3.54e-1)" "unprognostic (4.54e-2)" "unprognostic (1.47e-1)" "unprognostic (1.38e-1)" "unprognostic (5.31e-2)" "unprognostic (4.70e-2)" "unprognostic (1.44e-5)" "unprognostic (2.21e-1)" "unprognostic (5.97e-2)" "unprognostic (7.84e-2)" "unprognostic (9.01e-2)" 0.4 0.2 1.1 3.8 1.1 2.2 4.3 3.6 1.3 14.0 0.0 146.7 305.0 0.9 1.1 0.6 0.9 0.4 0.4 0.7 1.6 4.1 0.7 0.6 0.8 0.5 0.1 0.4 0.5 0.1 0.0 1.4 0.9 3.8 147.4 1.3 0.8 4.5 1.2 149.7 250.5 6.5 0.1 0.3 1.1 7.3 0.9 0.5 0.6 0.2 0.4 9.0 4.2 2.9 1.0 2.2 0.5 0.6 1.2 1.3 1.2 2.9 1.1 0.3 1.0 0.5 2.3 0.4 0.9 2.5 1.2 1.4 0.4 2.9 0.6 0.7 0.2 0.5 4.1 1.6 1.7 0.3 0.7 0.9 0.8 2.5 7.3 10.2 1.1 0.3 1.2 1.0 1.2 0.1 0.1 8.7 0.3 0.5 2.1 0.2 0.1 1.4 1.1 0.7 0.6 0.7 0.8 0.2 0.0 0.6 0.2 0.2 1.3 0.5 0.6 0.7 0.1 0.4 0.1 0.2 0.0 0.5 0.5 0.1 0.1 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.4 0.0 0.1 0.1 0.0 0.0 1.1 1.1 3.6 1.3 0.7 1.6 0.5 0.1 0.9 0.1 0.9 2.9 0.0 0.0 0.0 0.0 0.0 10.3 8.7 6.1 0.0 0.0 0.0 0.1 0.1 0.0 24.4 1.8 0.0 0.9 0.0 345.0 0.0 0.0 0.6 1.3 0.5 0.2 9.1 0.0 0.0 0.0 4.1 0.2 0.0 3.6 4.5 0.7 0.0 0.0 0.1 0.0 0.0 70.0 12.2 0.0 1.6 0.5 0.0 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.6 0.0 274.0 0.0 0.0 2.5 654.2 12.9 4.4 0.0 0.0 0.0 0.3 0.0 0.2 0.0 67.5 0.7 0.2 0.2 205.4 29.9 CHRM4 ENSG00000180720 "Cholinergic receptor muscarinic 4" P08173 11 46385098-46386608 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 18.5;intestine: 6.8;lymphoid tissue: 15.9;testis: 5.0" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Group enriched" "Detected in many" 6 "basal ganglia: 18.5;cerebral cortex: 4.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "RH-30: 3.4;SCLC-21H: 10.0;U-2 OS: 2.8" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "basal ganglia: 16.8" "CAB022444, HPA072083" Enhanced Uncertain "Nucleoplasm,Golgi apparatus" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" Nucleoplasm "CAB022444: , HPA072083: " "unprognostic (7.11e-2)" "unprognostic (3.79e-1)" "unprognostic (5.31e-2)" "unprognostic (7.38e-2)" "unprognostic (8.63e-3)" "unprognostic (1.38e-1)" "unprognostic (6.02e-2)" "unprognostic (1.03e-1)" "unprognostic (1.48e-1)" "unprognostic (2.96e-3)" "unprognostic (4.08e-3)" "unprognostic (5.02e-2)" "unprognostic (3.83e-2)" "unprognostic (3.64e-1)" "unprognostic (1.71e-1)" "unprognostic (3.56e-1)" "unprognostic (5.08e-2)" 0.1 0.5 1.6 0.2 18.5 1.7 0.1 0.0 4.6 0.1 0.0 1.5 3.2 0.1 0.0 0.0 0.1 0.0 0.1 1.8 0.1 0.0 0.0 0.3 0.1 0.2 0.0 0.0 0.2 0.2 1.2 0.0 0.0 0.0 0.1 2.4 0.1 0.0 0.0 2.0 6.8 0.1 0.0 15.9 0.6 5.0 1.7 2.4 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.5 0.2 0.0 0.1 0.0 2.1 0.0 0.1 0.1 0.1 1.0 0.1 0.2 0.2 0.0 1.8 0.1 1.3 0.1 0.0 1.6 0.2 0.4 0.1 0.0 0.1 0.3 0.4 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.4 0.1 0.0 0.7 0.2 0.1 0.4 0.1 0.1 0.0 3.4 0.0 0.0 0.1 10.0 0.2 0.2 0.0 0.1 0.2 0.1 1.7 0.0 0.3 2.8 0.0 0.0 0.5 0.4 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 18.5 0.0 4.6 1.8 0.1 0.2 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CIDEC "CIDE-3, FLJ20871, Fsp27" ENSG00000187288 "Cell death inducing DFFA like effector c" Q96AQ7 3 9866711-9880255 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "adipose tissue: 740.3;breast: 492.9" "Cell type enriched" "Detected in some" 7 "Proximal enterocytes: 219.4" "Group enriched" "Detected in many" 5 "breast cancer: 4.5;colorectal cancer: 1.4;liver cancer: 2.4;pancreatic cancer: 4.6;stomach cancer: 2.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "ASC diff: 1683.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA018837, HPA020553" Uncertain NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "HPA018837: AB_1846767, HPA020553: AB_1846769" "unprognostic (1.83e-2)" "unprognostic (3.08e-2)" "unprognostic (2.32e-1)" "unprognostic (1.83e-1)" "unprognostic (1.19e-1)" "unprognostic (7.80e-2)" "unprognostic (1.66e-3)" "unprognostic (1.26e-5)" "unprognostic (9.03e-2)" "unprognostic (1.81e-1)" "unprognostic (5.48e-3)" "unprognostic (8.14e-2)" "unprognostic (5.37e-5)" "unprognostic (9.47e-3)" "unprognostic (2.02e-1)" "unprognostic (7.46e-3)" "unprognostic (2.94e-2)" 740.3 5.6 0.1 1.1 0.2 0.0 492.9 0.0 0.4 1.2 0.0 15.9 68.9 4.6 0.3 0.7 2.2 5.0 9.5 0.1 0.1 2.1 10.0 0.2 1.2 0.1 0.2 0.4 7.4 0.1 0.2 0.0 0.2 2.3 3.9 0.0 16.2 3.7 6.1 18.1 89.8 1.6 0.1 0.2 7.4 0.9 0.2 1.5 3.9 11.6 0.0 13.3 4.8 0.2 0.0 0.2 0.0 0.0 1683.2 376.0 1.2 0.1 0.0 0.0 0.0 7.5 9.1 0.0 0.2 0.6 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.0 0.0 19.1 2.8 0.0 0.0 228.9 0.4 0.0 0.3 0.1 0.0 0.0 0.1 0.1 0.1 0.6 0.0 0.3 0.0 0.6 1.6 0.0 0.0 1.0 0.0 0.0 0.4 0.2 0.0 0.0 0.1 0.1 0.0 0.5 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.2 0.0 0.4 0.1 0.1 0.1 0.2 0.2 0.1 0.2 0.2 2.3 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.1 2.0 0.2 0.0 0.0 0.0 0.0 0.0 1.5 30.0 1.9 0.0 0.5 0.2 0.1 0.1 3.5 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.0 1.2 0.0 0.0 0.1 8.4 0.0 0.0 0.4 1.0 2.5 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.8 14.5 0.4 0.0 0.4 219.4 1.1 0.0 0.0 0.0 0.5 0.6 0.6 0.4 0.0 0.0 0.0 0.2 0.1 3.8 0.3 CKS2 ENSG00000123975 "CDC28 protein kinase regulatory subunit 2" P33552 9 89311195-89316703 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 177.3;testis: 186.3" "Cell type enhanced" "Detected in many" "Langerhans cells: 474.6;Spermatocytes: 692.7;Spermatogonia: 503.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 187.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003424, HPA030762" Approved Approved Nucleoplasm,Vesicles,Mitochondria,Cytosol NA Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" "Mitochondria, Cytosol" "Nucleoplasm, Vesicles" "HPA003424: AB_2666948, HPA030762: AB_10670044" "unprognostic (8.30e-2)" "unprognostic (3.00e-1)" "unprognostic (1.50e-2)" "unprognostic (2.80e-2)" "unprognostic (2.96e-1)" "unprognostic (1.35e-1)" "prognostic unfavorable (2.51e-6)" "unprognostic (3.57e-3)" "unprognostic (7.04e-2)" "unprognostic (1.34e-2)" "prognostic unfavorable (6.85e-4)" "unprognostic (1.24e-2)" "prognostic unfavorable (1.78e-5)" "unprognostic (2.13e-3)" "unprognostic (1.44e-1)" "unprognostic (2.84e-1)" "unprognostic (1.84e-1)" 13.6 82.9 9.6 38.5 10.0 177.3 20.1 11.9 26.9 10.1 11.8 44.1 43.3 13.0 8.8 53.2 12.1 18.7 10.3 12.7 10.3 35.6 31.2 24.0 102.8 10.5 10.1 9.4 4.2 19.8 4.8 44.3 11.0 15.0 41.0 27.9 10.8 17.8 9.4 19.9 33.1 17.6 10.6 32.6 20.4 186.3 10.8 121.1 12.8 4.8 84.7 26.5 19.9 11.3 685.9 570.1 342.6 230.6 98.7 89.1 249.5 396.1 211.4 428.1 340.0 236.1 328.6 504.9 228.4 149.1 761.4 466.5 415.5 305.1 488.2 398.1 335.5 257.5 378.9 637.5 42.4 531.7 281.2 33.0 69.2 307.2 269.1 162.9 403.2 409.1 313.2 430.6 556.0 509.1 420.7 928.3 501.6 795.5 521.5 358.4 376.4 303.7 342.8 153.5 288.4 171.7 328.7 314.9 324.5 318.4 379.7 304.2 231.4 184.1 350.3 449.6 588.2 345.9 759.2 415.3 271.3 303.1 268.5 40.8 19.5 44.1 22.6 26.5 25.3 61.3 30.4 21.9 22.5 44.7 16.3 21.8 14.5 40.9 14.8 187.9 62.7 23.6 9.6 10.0 11.9 26.9 12.7 10.3 10.5 10.1 11.0 10.6 10.8 11.3 138.6 38.5 103.9 0.3 175.7 280.2 92.1 126.1 259.0 4.1 107.2 169.0 61.3 5.7 49.9 14.7 0.0 231.1 201.1 79.4 23.5 20.1 37.3 149.7 66.4 66.1 122.3 266.9 1.2 11.2 379.4 63.1 74.9 250.2 145.0 144.7 29.3 25.0 184.6 0.0 1.9 164.9 111.9 40.5 474.6 77.0 25.7 164.3 140.5 1.9 31.0 26.1 28.8 1.0 1.1 31.1 67.1 16.6 89.3 72.1 37.6 209.7 32.8 7.3 46.0 75.2 206.5 692.7 503.6 197.5 299.1 199.5 156.0 70.3 162.7 102.1 CLDN23 CLDNL ENSG00000253958 "Claudin 23" Q96B33 8 8701937-8704096 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 16.4;stomach 1: 15.6" "Group enriched" "Detected in many" 4 "Distal enterocytes: 418.8;Paneth cells: 449.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "myeloid DC: 1.3;plasmacytoid DC: 1.4" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "BEWO: 7.7;Daudi: 6.4;RT4: 6.7;SK-BR-3: 6.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA061306 Approved "Vesicles,Plasma membrane,Cell Junctions" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "Plasma membrane, Cell Junctions" "HPA061306: " "unprognostic (1.86e-1)" "unprognostic (1.53e-1)" "prognostic favorable (3.46e-4)" "unprognostic (2.97e-1)" "unprognostic (8.32e-2)" "unprognostic (3.04e-1)" "unprognostic (3.44e-1)" "unprognostic (2.05e-2)" "unprognostic (2.14e-1)" "unprognostic (1.14e-1)" "unprognostic (1.97e-2)" "unprognostic (8.25e-3)" "prognostic favorable (9.65e-8)" "unprognostic (7.76e-2)" "unprognostic (3.17e-2)" "unprognostic (9.59e-2)" "unprognostic (1.33e-3)" 6.2 1.1 0.3 2.3 0.4 0.1 5.7 0.2 0.3 2.4 2.3 16.4 4.1 1.0 1.9 3.3 1.4 1.2 0.7 0.3 0.3 4.5 10.4 4.7 0.3 0.5 0.4 1.6 4.0 2.1 0.9 1.5 0.4 1.3 6.8 0.1 6.8 1.3 0.5 13.5 10.1 0.3 0.4 1.8 15.6 0.5 0.5 0.1 4.9 0.3 0.3 5.0 2.7 0.6 0.1 2.6 0.0 0.1 0.7 0.1 7.7 1.9 1.5 2.0 3.1 1.5 4.2 6.4 0.0 0.1 0.7 2.5 0.0 0.0 0.2 1.3 0.0 0.0 0.7 0.1 3.5 0.0 0.0 1.0 0.8 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.2 3.3 0.0 0.2 1.9 0.3 1.3 0.0 0.0 0.0 0.9 6.7 0.3 0.9 2.6 6.8 0.1 0.7 0.9 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.3 0.0 0.9 0.0 0.2 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.3 0.3 0.4 0.2 0.3 0.3 0.3 0.5 0.4 0.4 0.4 0.5 0.6 13.0 9.6 3.1 0.3 1.1 0.1 6.6 4.2 2.2 0.1 6.8 3.4 0.7 30.0 6.9 1.8 0.0 19.1 2.8 418.8 7.9 26.9 0.0 6.0 2.5 3.4 7.7 0.0 0.0 10.7 14.9 3.3 59.7 6.7 4.5 0.8 8.2 10.6 16.8 0.0 0.0 49.9 26.4 2.4 1.4 0.0 0.3 4.6 3.6 1.9 1.4 1.1 0.0 0.0 0.0 28.1 449.9 0.4 0.1 3.3 99.1 4.7 10.3 1.1 6.6 1.5 3.2 0.0 0.0 3.9 0.6 9.4 1.3 0.3 55.2 12.2 CLDN3 "C7orf1, CPE-R2, CPETR2, HRVP1, RVP1" ENSG00000165215 "Claudin 3" O15551 7 73768997-73770270 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cancer-related genes, Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 263.1;thyroid gland: 116.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 1839.9;Endometrial ciliated cells: 1221.7;Glandular and luminal cells: 1555.7;Intestinal goblet cells: 1471.3;Paneth cells: 2326.0;Proximal enterocytes: 3162.1;Undifferentiated cells: 1266.0" "Cancer enhanced" "Detected in many" "ovarian cancer: 529.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MCF7: 230.7;PC-3: 47.6;RPMI-8226: 40.5;SCLC-21H: 58.0;T-47d: 105.4" "Region enhanced" "Detected in single" "basal ganglia: 1.5" "Region enhanced" "Detected in many" "midbrain: 9.7" HPA014361 Enhanced Supported "Cell Junctions" NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 44: Endometrium - Transcription" "Cell Junctions" "HPA014361: AB_2668982" "unprognostic (1.84e-1)" "unprognostic (4.83e-2)" "unprognostic (2.05e-1)" "unprognostic (5.27e-2)" "unprognostic (2.61e-1)" "unprognostic (1.31e-1)" "unprognostic (2.79e-2)" "unprognostic (8.26e-2)" "unprognostic (3.11e-1)" "unprognostic (1.46e-1)" "unprognostic (2.28e-3)" "unprognostic (1.42e-1)" "prognostic favorable (3.39e-5)" "unprognostic (1.46e-2)" "unprognostic (1.87e-1)" "unprognostic (5.18e-2)" "unprognostic (6.72e-2)" 0.7 0.2 0.2 7.8 0.3 0.2 26.7 4.2 0.3 12.3 37.6 263.1 54.4 7.5 1.4 1.3 29.6 2.2 0.1 1.1 1.2 46.5 40.4 10.7 0.2 1.3 1.9 0.5 96.6 1.5 27.7 1.0 0.6 58.3 17.5 0.4 72.9 8.3 0.1 9.6 169.5 0.8 0.5 0.2 1.4 0.7 0.9 1.0 116.3 0.0 1.2 1.5 0.2 0.2 2.5 3.6 0.0 0.4 0.0 0.0 17.8 0.0 0.0 0.0 0.0 4.2 35.7 0.0 9.9 0.0 0.0 1.0 0.4 0.0 0.0 0.1 4.9 0.0 0.8 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 230.7 0.4 1.2 2.1 9.1 47.6 0.1 0.0 40.5 2.1 0.2 58.0 0.7 0.0 33.6 0.0 0.2 105.4 0.0 0.2 0.2 0.6 0.9 0.1 0.2 0.6 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 4.2 0.3 1.1 1.2 1.3 1.9 0.6 0.5 0.9 0.2 1.6 38.5 37.8 0.0 13.2 0.1 60.3 43.7 0.0 0.7 289.9 182.5 0.6 287.4 86.3 126.9 4.2 63.9 5.1 1839.9 9.8 297.5 0.0 1221.7 130.5 10.3 606.1 5.3 0.0 19.1 17.7 4.1 16.8 1555.7 28.0 1.5 0.4 40.5 5.1 0.0 0.0 1471.3 116.0 0.3 0.0 0.3 2.5 9.9 10.6 0.0 2.0 11.8 0.0 0.0 0.0 36.7 2326.0 0.0 4.4 433.2 3162.1 58.6 498.4 10.6 0.0 0.0 20.3 0.1 0.3 2.7 0.0 72.4 17.5 0.0 1266.0 607.3 CLDN7 "CEPTRL2, CPETRL2, Hs.84359" ENSG00000181885 "Claudin 7" O95471 17 7259903-7263983 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 341.3;intestine: 341.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 1391.1;Pancreatic endocrine cells: 822.1;Paneth cells: 1276.4;Proximal enterocytes: 1390.9;Urothelial cells: 975.8" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BEWO: 84.1;CACO-2: 90.2;CAPAN-2: 173.2;HaCaT: 364.9;MCF7: 129.8;OE19: 139.6;SK-BR-3: 150.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB013063, HPA014703, HPA073662" Enhanced Approved "Vesicles,Cell Junctions" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "Cell Junctions" "CAB013063: , HPA014703: AB_1846873, HPA073662: " "unprognostic (5.47e-2)" "unprognostic (2.22e-1)" "unprognostic (4.12e-2)" "unprognostic (2.90e-1)" "unprognostic (1.05e-1)" "unprognostic (8.67e-2)" "unprognostic (3.41e-2)" "unprognostic (1.98e-2)" "unprognostic (5.64e-3)" "unprognostic (8.34e-2)" "unprognostic (4.89e-3)" "unprognostic (1.62e-2)" "prognostic favorable (8.96e-11)" "prognostic favorable (4.09e-4)" "unprognostic (1.87e-1)" "prognostic favorable (1.85e-4)" "unprognostic (1.62e-1)" 6.7 8.0 0.4 17.6 0.4 0.2 31.2 0.5 0.6 47.3 0.4 341.0 146.7 4.8 43.9 341.3 41.3 27.4 2.7 0.4 0.4 123.8 40.2 61.8 0.8 0.6 0.5 1.5 108.5 49.0 31.1 14.2 0.6 44.5 128.6 1.1 169.2 30.0 1.5 13.1 248.9 6.2 0.5 5.7 5.2 1.9 0.6 2.4 76.7 0.0 21.2 40.5 96.3 0.9 10.8 1.1 0.2 0.3 0.0 0.6 84.1 0.3 0.3 0.0 0.0 90.2 173.2 0.1 3.2 0.4 0.4 364.9 0.1 11.2 0.0 0.1 1.9 0.1 2.4 0.0 6.5 0.1 0.8 1.5 17.3 0.0 0.6 0.0 8.1 0.1 1.0 0.3 0.1 129.8 0.1 1.2 0.6 139.6 3.4 0.2 0.0 2.5 0.1 0.0 20.4 0.4 1.1 150.2 0.0 6.6 55.0 1.3 16.8 0.2 0.6 0.7 0.2 0.1 0.3 0.1 1.2 0.0 0.3 0.0 0.3 0.0 0.5 0.8 1.3 0.1 0.3 0.8 0.4 0.9 0.9 1.7 0.0 0.7 0.0 0.0 0.3 0.5 0.4 0.4 0.5 0.6 0.4 0.4 0.6 0.5 0.6 0.5 0.6 0.9 4.4 112.2 55.6 0.0 7.4 2.0 295.4 316.3 66.6 0.7 200.4 102.4 0.6 240.2 550.3 321.8 8.4 281.3 3.1 1391.1 39.2 787.5 0.1 210.1 26.6 9.0 326.8 4.0 0.0 790.0 342.7 5.2 15.3 225.5 5.7 0.1 3.6 41.2 33.7 0.0 0.0 741.7 362.2 4.1 6.4 0.2 1.2 11.0 24.9 1.9 11.0 1.6 0.0 0.0 0.0 822.1 1276.4 0.0 0.5 406.5 1390.9 78.6 498.5 6.7 0.0 0.2 38.6 0.4 3.5 366.1 2.6 588.9 10.2 1.0 691.9 975.8 CLEC11A "CLECSF3, LSLCL, P47, SCGF" ENSG00000105472 "C-type lectin domain containing 11A" Q9Y240 19 50723364-50725718 "Plasma proteins, Predicted secreted proteins" Osteogenesis "Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 132.6" "Cell type enhanced" "Detected in many" "Distal tubular cells: 119.3;Fibroblasts: 107.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 24.3" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 4 "HEL: 363.0;HMC-1: 637.3;NB-4: 901.1;THP-1: 694.7;U-937: 358.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA042690 Approved Approved Centrosome "Secreted in other tissues" NA NA 1300000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 24: NB-4 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" Centrosome "HPA042690: AB_10795511" "unprognostic (9.33e-2)" "unprognostic (6.66e-2)" "unprognostic (2.40e-2)" "prognostic favorable (6.91e-4)" "unprognostic (2.33e-1)" "unprognostic (8.22e-2)" "unprognostic (5.52e-2)" "unprognostic (1.29e-2)" "unprognostic (5.26e-2)" "unprognostic (4.99e-2)" "unprognostic (2.79e-2)" "unprognostic (8.30e-2)" "prognostic unfavorable (1.02e-5)" "unprognostic (6.09e-2)" "unprognostic (8.66e-3)" "unprognostic (4.00e-2)" "unprognostic (1.57e-2)" 17.5 17.5 5.0 7.0 5.6 132.6 14.1 7.9 9.1 44.4 2.9 12.0 4.8 31.9 1.6 8.4 37.5 6.2 16.3 4.4 7.2 21.1 12.1 15.0 2.7 10.2 7.9 31.5 7.5 2.4 22.3 5.5 8.1 22.5 1.9 0.7 6.9 4.8 4.4 16.8 9.7 8.1 7.2 14.0 8.0 9.1 6.2 2.6 12.8 1.0 0.8 19.2 28.2 6.0 2.6 3.5 0.0 2.9 33.7 45.3 79.2 139.3 37.9 15.6 15.7 0.1 0.0 0.4 1.7 70.2 0.8 1.6 0.4 0.2 10.7 0.6 22.9 363.0 0.1 0.0 21.3 0.2 637.3 33.7 0.2 1.9 2.3 0.1 17.9 16.1 4.1 2.2 29.0 2.6 3.1 901.1 1.6 0.3 4.6 30.7 0.2 0.2 0.8 0.4 0.0 3.8 4.2 0.0 58.1 0.0 0.9 694.7 100.3 1.1 41.6 0.7 0.7 2.1 2.2 0.5 47.3 358.7 44.2 1.4 24.3 0.4 0.9 11.5 0.1 0.6 0.3 0.2 17.7 0.4 2.0 4.5 1.6 5.7 5.6 4.8 0.2 8.2 5.0 5.6 7.9 9.1 4.4 7.2 10.2 7.9 8.1 7.2 6.2 6.0 12.4 3.2 5.4 10.4 3.9 32.0 32.2 2.9 27.3 20.5 30.8 31.9 3.4 8.6 4.0 29.5 10.4 8.6 5.0 1.7 119.3 11.0 6.5 17.0 70.7 16.9 26.5 36.4 9.0 3.1 72.4 107.2 4.1 14.1 5.7 18.9 51.4 6.3 49.4 21.9 8.3 4.5 10.2 21.5 73.3 19.9 70.8 29.6 78.2 9.4 11.2 70.4 14.4 8.0 12.9 3.1 1.7 67.4 0.9 21.4 0.5 13.7 5.0 20.7 65.7 20.2 59.2 17.2 21.7 26.3 45.9 18.3 5.8 56.7 3.5 17.8 CLEC1A "CLEC1, MGC34328" ENSG00000150048 "C-type lectin domain family 1 member A" Q8NC01 12 10069554-10111627 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 50.2;placenta: 49.0" "Cell type enhanced" "Detected in some" "Adipocytes: 51.4;Cytotrophoblasts: 51.5;Endothelial cells: 38.1;Extravillous trophoblasts: 61.7;Syncytiotrophoblasts: 52.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 2.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BEWO: 21.3;HUVEC TERT2: 18.3;SuSa: 5.6;U-266/70: 4.9;U-266/84: 11.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "unprognostic (7.63e-2)" "unprognostic (2.51e-2)" "unprognostic (5.96e-2)" "unprognostic (2.02e-2)" "unprognostic (1.09e-1)" "unprognostic (1.16e-2)" "unprognostic (1.37e-1)" "unprognostic (1.03e-1)" "unprognostic (7.15e-2)" "unprognostic (2.73e-2)" "unprognostic (3.26e-2)" "unprognostic (1.81e-1)" "unprognostic (3.35e-3)" "unprognostic (3.94e-2)" "unprognostic (1.28e-1)" "unprognostic (1.20e-1)" "unprognostic (2.02e-2)" 16.2 3.2 4.4 4.1 4.2 0.4 14.8 6.6 5.6 11.4 4.1 4.3 1.5 6.8 2.7 3.8 9.2 5.7 9.0 3.9 3.8 5.8 2.9 29.8 5.9 4.8 4.5 5.4 2.3 1.6 3.7 49.0 4.7 6.3 2.0 0.6 2.9 2.4 3.9 4.1 4.4 8.7 4.3 8.0 3.7 2.1 5.1 50.2 7.6 4.4 3.5 6.1 8.6 4.1 0.0 0.0 0.3 0.3 0.2 0.2 21.3 0.1 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.4 1.2 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.1 0.0 0.4 0.2 0.0 0.0 0.1 0.0 0.0 0.0 18.3 0.0 0.0 1.9 0.0 0.0 0.0 0.4 3.0 0.0 0.4 0.0 0.0 0.1 0.1 0.2 0.4 0.0 0.3 0.3 0.0 5.6 0.0 0.0 1.4 0.0 0.2 0.2 0.0 4.9 11.5 0.0 0.2 0.1 0.0 0.1 0.9 0.0 0.0 0.5 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 1.1 0.0 0.2 0.0 0.0 0.2 4.4 4.2 6.6 5.6 3.9 3.8 4.8 4.5 4.7 4.3 5.1 4.1 51.4 0.0 0.5 0.0 0.5 2.2 0.1 0.0 1.2 0.0 0.3 0.1 1.3 0.0 0.0 0.0 0.0 51.5 0.2 0.0 0.0 0.0 0.4 0.0 0.1 38.1 0.0 0.0 0.0 0.0 61.7 1.2 0.0 0.0 0.0 0.0 16.8 0.2 5.0 0.0 0.0 0.0 0.0 4.7 14.1 0.6 7.5 4.0 3.6 11.2 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.9 4.0 2.9 0.3 1.6 52.1 0.6 0.3 0.0 0.5 CLEC4E "CLECSF9, mincle" ENSG00000166523 "C-type lectin domain family 4 member E" Q9ULY5 12 8533305-8540905 "Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 75.7;lymphoid tissue: 52.3" "Cell type enhanced" "Detected in some" "Glandular and luminal cells: 31.9;Kupffer cells: 158.0;Macrophages: 115.2;monocytes: 109.5" "Cancer enhanced" "Detected in many" "testis cancer: 6.0" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 16 "classical monocyte: 128.8;neutrophil: 448.8" "Group enriched" "Detected in many" 17 "granulocytes: 448.8;monocytes: 128.8" "Group enriched" "Detected in some" 4 "NB-4: 4.3;RPTEC TERT1: 12.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA004935 Uncertain Uncertain Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 41: Macrophages - Immune response" Cytosol "HPA004935: AB_2667299" "unprognostic (3.05e-2)" "unprognostic (2.01e-2)" "unprognostic (8.91e-2)" "unprognostic (3.76e-1)" "unprognostic (1.76e-1)" "unprognostic (9.71e-3)" "unprognostic (1.77e-1)" "unprognostic (1.24e-1)" "unprognostic (9.29e-2)" "unprognostic (1.83e-1)" "unprognostic (1.16e-1)" "unprognostic (2.11e-2)" "unprognostic (7.65e-3)" "unprognostic (1.62e-1)" "unprognostic (1.51e-1)" "unprognostic (8.44e-2)" "unprognostic (2.29e-1)" 13.3 5.4 2.3 37.5 2.1 75.7 4.5 1.8 4.4 5.8 2.2 2.2 0.4 2.3 0.4 3.2 5.5 11.8 2.5 2.3 2.9 3.6 6.6 22.4 7.6 1.3 1.3 1.7 6.2 1.7 1.9 2.1 1.2 2.3 1.0 1.3 1.4 1.2 0.7 0.9 3.1 5.7 0.7 52.3 2.5 1.1 2.0 2.2 10.5 5.0 2.3 9.6 1.7 2.9 0.1 0.4 0.4 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.1 1.5 0.1 0.1 2.0 0.0 0.1 0.1 0.2 0.2 0.1 0.3 0.2 0.2 0.1 0.5 0.1 0.0 1.5 0.0 0.5 0.2 0.2 0.2 0.2 0.0 0.1 0.0 4.3 0.3 0.0 0.0 0.0 0.2 0.1 12.4 0.1 0.0 0.2 0.0 0.0 0.1 0.4 0.0 0.4 1.0 0.5 0.1 1.0 0.1 0.2 0.1 0.1 1.3 0.4 0.1 0.2 128.8 0.5 0.1 18.1 0.3 0.1 0.1 0.1 16.9 0.1 0.0 0.1 448.8 0.0 0.7 0.7 0.0 30.3 2.3 2.1 1.8 4.4 2.3 2.9 1.3 1.3 1.2 0.7 2.0 2.9 6.2 0.0 4.7 0.0 1.5 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 5.7 1.8 1.8 0.0 0.0 0.3 0.0 0.0 9.0 0.3 2.1 4.4 3.5 0.0 0.0 0.0 0.0 0.1 1.4 0.0 31.9 0.0 0.0 7.1 2.1 5.6 0.0 0.0 0.0 0.0 158.0 9.0 2.9 0.9 115.2 0.0 0.0 109.5 0.0 4.1 0.0 0.0 0.4 0.0 0.4 1.3 0.0 0.0 0.2 0.7 0.0 13.1 0.2 0.4 0.2 0.5 0.1 0.0 0.1 1.1 0.0 0.0 0.1 CLGN ENSG00000153132 Calmegin O14967 4 140388453-140427661 "Predicted intracellular proteins, Predicted membrane proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 59.5;testis: 113.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 313.3;Early spermatids: 162.4;Endometrial ciliated cells: 93.4;Muller glia cells: 176.4;Spermatocytes: 465.5" "Cancer enhanced" "Detected in many" "prostate cancer: 19.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 53.0;MOLT-4: 47.8;U-251 MG: 73.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020709, HPA048761, HPA058627" Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 43: Testis - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 66: Spermatocytes - Spermatogenesis" "Endoplasmic reticulum" "CAB020709: , HPA048761: AB_2680514, HPA058627: AB_2683782" "unprognostic (6.74e-2)" "unprognostic (8.28e-2)" "unprognostic (1.62e-1)" "unprognostic (1.08e-1)" "unprognostic (2.30e-2)" "unprognostic (2.56e-1)" "unprognostic (3.73e-3)" "unprognostic (6.14e-2)" "unprognostic (4.80e-2)" "unprognostic (3.11e-1)" "unprognostic (5.38e-3)" "unprognostic (2.29e-2)" "unprognostic (2.45e-3)" "unprognostic (3.00e-3)" "unprognostic (1.29e-1)" "unprognostic (2.59e-1)" "unprognostic (1.01e-1)" 0.4 6.6 0.9 1.0 0.7 2.4 2.7 3.8 1.6 0.9 2.0 2.6 0.5 1.6 0.6 1.2 13.7 0.4 59.5 0.9 2.6 0.4 3.2 0.5 0.7 2.7 1.9 0.3 2.2 0.6 11.2 0.2 2.6 22.5 1.3 17.2 1.0 0.7 0.4 0.2 1.3 1.5 1.2 0.2 2.0 113.6 2.3 2.4 2.7 1.6 1.2 0.6 0.1 0.9 0.2 10.2 10.3 6.9 4.0 21.1 2.4 0.1 9.4 10.0 18.6 0.3 0.9 0.0 27.8 0.9 8.4 0.2 7.5 0.1 16.2 0.4 9.0 3.0 9.8 7.4 41.4 38.9 0.6 2.2 39.2 1.0 0.9 53.0 0.2 9.6 2.0 0.0 0.0 0.5 47.8 0.5 12.0 0.2 28.1 31.5 0.0 0.4 0.0 0.3 16.8 29.8 6.5 4.1 1.8 3.8 1.9 5.6 0.0 27.4 4.7 9.7 73.6 14.4 31.7 19.9 43.4 1.6 2.9 0.9 0.2 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.7 3.8 1.6 0.9 2.6 2.7 1.9 2.6 1.2 2.3 0.9 0.8 0.0 2.2 0.3 0.1 0.0 0.9 8.5 1.2 9.2 3.3 1.8 313.3 0.0 6.4 0.0 4.2 0.5 0.0 0.5 0.0 1.2 162.4 93.4 1.3 11.9 5.3 8.6 7.2 4.2 0.1 10.2 0.0 11.3 0.0 10.1 0.7 3.7 0.1 25.2 6.7 0.4 30.5 0.0 0.0 60.2 5.0 0.7 1.8 0.0 0.1 176.4 0.0 6.6 0.6 0.9 3.9 4.5 0.1 33.8 0.2 0.1 24.6 16.3 0.0 0.6 2.0 465.5 23.9 2.8 0.1 0.3 0.7 0.2 0.8 1.3 CLIC1 "CLCNL1, G6, NCC27, p64CLCP" ENSG00000213719 "Chloride intracellular channel 1" O00299 6 31730581-31739763 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Voltage-gated channel" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020825, CAB040557" Enhanced Supported Cytosol NA NA 22000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 72: Non-specific - Transcription" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" Cytosol "CAB020825: , CAB040557: " "unprognostic (7.26e-2)" "unprognostic (9.32e-2)" "unprognostic (2.78e-3)" "unprognostic (7.29e-2)" "unprognostic (6.93e-2)" "unprognostic (2.73e-2)" "prognostic unfavorable (8.90e-7)" "unprognostic (2.58e-2)" "unprognostic (8.51e-2)" "unprognostic (8.71e-3)" "unprognostic (1.19e-3)" "unprognostic (1.34e-1)" "prognostic unfavorable (8.11e-5)" "unprognostic (4.51e-2)" "unprognostic (2.89e-1)" "unprognostic (1.35e-2)" "unprognostic (7.31e-2)" 292.8 156.5 6.9 43.4 6.8 64.0 256.7 7.1 11.0 222.2 8.7 291.6 37.0 197.9 20.9 395.9 190.5 43.7 183.7 6.7 10.2 318.5 102.6 330.4 44.1 9.4 7.7 149.8 148.1 20.1 111.5 45.5 8.9 217.0 64.0 2.6 251.3 22.3 47.3 324.8 231.6 32.7 8.9 332.6 247.8 41.0 9.6 35.2 180.8 11.1 58.1 257.7 246.8 8.9 119.5 54.1 87.0 45.6 56.6 118.6 43.3 52.8 105.4 92.6 77.9 125.2 87.2 48.7 73.6 186.0 116.9 70.2 65.8 154.9 124.4 38.9 34.4 93.0 43.4 109.3 73.0 164.3 125.9 74.3 80.5 157.0 148.4 101.7 157.9 44.6 109.4 149.5 181.0 79.2 77.2 213.2 7.7 128.9 78.4 13.5 47.5 115.3 210.2 73.0 16.5 19.5 43.1 49.1 71.5 60.4 33.7 228.3 105.0 128.6 91.2 39.0 166.8 48.3 98.3 66.0 62.4 122.0 136.6 244.3 179.4 239.3 165.6 194.3 135.8 186.1 98.0 155.5 143.8 150.3 30.5 92.3 341.1 176.3 174.3 80.5 149.2 414.2 6.9 6.8 7.1 11.0 6.7 10.2 9.4 7.7 8.9 8.9 9.6 8.9 514.8 70.5 67.0 0.7 382.5 960.8 589.1 869.7 331.2 0.4 274.3 300.5 18.6 296.0 457.7 237.3 0.0 545.5 472.2 730.7 602.6 1096.2 31.8 271.1 212.7 490.1 381.4 208.6 0.0 1008.9 912.5 296.6 370.5 301.3 554.1 431.2 300.9 54.2 1047.6 0.0 0.0 665.6 516.8 533.7 1529.8 17.3 233.9 685.7 524.7 13.1 426.4 86.8 706.5 0.5 0.0 1470.4 997.1 188.1 420.2 851.1 707.7 572.1 473.6 6.9 203.8 136.1 554.0 28.7 16.2 464.1 928.0 572.7 522.2 283.3 675.0 1005.9 CLSPN ENSG00000092853 Claspin Q9HAW4 1 35720218-35769978 "Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 11.3;lymphoid tissue: 7.9;retina: 6.8;testis: 5.7" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 101.0;Spermatocytes: 281.1;Spermatogonia: 263.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Region enriched" "Detected in some" 6 "basal ganglia: 7.8" "Low region specificity" "Detected in many" "HPA026305, HPA026312" Enhanced "Nucleoplasm,Golgi apparatus" Yes Yes "Cluster 17: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoplasm, Golgi apparatus" "HPA026305: AB_2671833, HPA026312: AB_2671837" "unprognostic (4.75e-2)" "unprognostic (1.01e-1)" "unprognostic (9.64e-3)" "unprognostic (3.54e-2)" "unprognostic (6.82e-2)" "unprognostic (1.62e-2)" "unprognostic (1.18e-6)" "unprognostic (3.99e-3)" "unprognostic (2.08e-3)" "unprognostic (1.63e-2)" "unprognostic (8.71e-6)" "unprognostic (3.23e-2)" "unprognostic (7.61e-6)" "prognostic favorable (4.92e-4)" "unprognostic (5.12e-1)" "unprognostic (1.73e-1)" "unprognostic (1.29e-1)" 0.5 0.2 0.7 3.2 0.6 11.3 0.5 0.6 1.4 0.2 0.4 1.4 1.0 0.4 0.7 0.9 0.2 0.3 0.1 1.3 0.3 0.2 0.5 0.4 4.9 0.4 0.4 0.1 0.1 0.2 0.0 1.5 0.6 0.2 2.0 6.8 0.2 0.1 0.6 1.2 1.0 0.9 0.2 1.3 0.9 5.7 0.6 7.9 0.2 0.0 5.2 0.6 0.4 0.9 22.0 17.5 37.8 19.9 2.6 4.8 14.1 43.6 12.0 31.0 41.3 27.9 19.6 45.7 13.9 11.8 22.7 21.4 37.1 14.9 48.1 31.6 16.8 64.5 38.1 12.6 0.1 54.0 36.8 1.0 0.6 53.8 3.7 3.7 16.9 27.1 44.2 30.8 30.3 14.1 56.9 13.1 36.0 14.9 12.2 36.0 57.0 13.8 6.4 35.3 14.0 16.2 37.7 11.6 7.4 25.6 10.0 21.1 12.5 44.6 33.8 27.6 49.3 11.1 29.1 47.1 14.1 37.4 37.0 1.1 0.3 0.3 0.3 0.2 0.1 0.1 0.2 0.2 0.2 0.3 0.1 0.2 1.0 0.5 0.2 0.2 0.3 0.3 0.7 0.6 0.6 1.4 1.3 0.3 0.4 0.4 0.6 0.2 0.6 0.9 2.6 0.0 0.5 0.3 6.5 5.6 5.7 4.4 1.2 9.4 2.9 3.8 1.4 2.8 2.7 0.0 12.5 19.7 4.6 12.8 0.0 1.6 7.9 1.0 3.6 3.6 1.2 55.6 1.6 0.6 41.1 5.2 4.6 3.3 1.3 12.0 2.2 0.4 16.9 1.7 1.5 9.4 2.0 3.0 8.2 6.1 2.5 5.8 3.6 0.0 9.1 9.4 4.1 0.0 0.6 1.4 9.5 0.4 32.5 1.8 0.4 0.2 0.0 101.0 6.6 5.3 8.7 281.1 263.3 5.8 2.0 10.4 7.2 1.2 12.0 3.9 CLSTN1 "CDHR12, CSTN1, KIAA0911" ENSG00000171603 "Calsyntenin 1" O94985 1 9728926-9823984 "Cancer-related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 437.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012412, HPA077705" Enhanced NA NA 86000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 68: Epididymis - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA012412: AB_1846981, HPA077705: " "unprognostic (4.63e-2)" "unprognostic (2.89e-1)" "unprognostic (9.76e-2)" "unprognostic (1.43e-1)" "unprognostic (9.79e-2)" "unprognostic (1.63e-1)" "unprognostic (2.44e-3)" "unprognostic (3.07e-2)" "unprognostic (2.54e-1)" "unprognostic (3.24e-2)" "unprognostic (1.34e-1)" "unprognostic (1.25e-1)" "prognostic favorable (4.10e-7)" "unprognostic (1.12e-1)" "unprognostic (2.65e-1)" "unprognostic (4.05e-2)" "unprognostic (4.72e-2)" 28.1 27.4 49.7 23.1 65.8 10.8 31.7 29.5 137.5 61.2 80.6 59.5 29.2 85.4 21.4 51.4 69.8 48.1 35.9 79.6 15.5 41.3 6.1 29.6 33.5 24.7 18.4 60.2 65.7 36.2 48.4 35.7 32.8 61.8 38.2 110.8 79.0 45.7 23.1 83.5 41.1 49.4 7.0 28.3 31.0 15.0 23.5 35.0 40.0 28.9 27.1 38.0 59.9 45.9 120.9 55.4 52.5 64.8 71.1 50.1 35.0 80.5 71.4 82.0 70.2 32.1 235.0 90.5 203.1 95.2 52.6 157.7 41.2 245.6 32.1 114.2 74.6 27.3 53.0 39.6 116.1 46.3 41.4 58.0 156.5 105.9 50.0 78.6 113.9 52.7 13.1 52.6 35.8 47.2 53.2 26.6 37.9 53.1 59.7 80.6 21.4 42.9 73.1 20.9 91.4 53.7 94.8 160.1 79.1 22.1 34.7 73.9 155.0 89.3 80.5 56.6 109.9 75.6 75.4 124.3 72.2 79.6 95.7 6.2 0.6 2.3 3.0 0.8 1.5 0.8 1.9 2.3 1.4 1.0 1.3 1.2 0.2 0.4 0.9 0.8 1.6 1.5 49.7 65.8 29.5 137.5 79.6 15.5 24.7 18.4 32.8 7.0 23.5 45.9 40.2 28.9 15.7 63.6 23.7 43.8 61.0 73.7 84.2 205.1 53.3 47.0 14.7 55.8 44.6 51.5 437.9 34.1 35.0 221.1 1.9 29.2 4.5 44.6 47.0 36.0 30.7 17.9 150.9 38.8 14.3 40.6 29.6 52.2 11.4 54.0 35.3 2.2 28.8 180.0 138.1 96.5 14.2 24.2 13.3 5.6 46.3 21.3 32.0 46.9 21.0 160.9 28.8 90.0 56.0 59.7 66.9 50.4 31.2 42.4 54.9 27.9 68.3 165.6 85.5 39.5 31.4 24.6 37.5 44.5 26.1 19.2 33.8 47.2 59.6 42.7 CLSTN3 "CDHR14, CSTN3, KIAA0726" ENSG00000139182 "Calsyntenin 3" Q9BQT9 12 7129698-7158945 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 161.2;Cone photoreceptor cells: 62.6;Excitatory neurons: 79.4;Inhibitory neurons: 60.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "NK-cell: 6.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 1700000 "Cluster 48: NK-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 28: BEWO - Transcription regulation" "Cluster 56: Bipolar cells - Visual perception" "prognostic favorable (5.08e-4)" "unprognostic (2.84e-2)" "unprognostic (1.06e-3)" "unprognostic (1.33e-2)" "unprognostic (6.73e-3)" "unprognostic (6.35e-2)" "unprognostic (9.52e-2)" "unprognostic (2.58e-1)" "unprognostic (2.94e-1)" "unprognostic (1.85e-1)" "prognostic favorable (1.19e-5)" "unprognostic (1.16e-1)" "prognostic unfavorable (4.49e-5)" "unprognostic (2.19e-2)" "unprognostic (6.14e-2)" "unprognostic (1.91e-1)" "prognostic favorable (8.07e-4)" 12.9 14.5 23.1 13.6 20.8 12.4 13.3 18.6 42.7 13.4 0.0 8.3 6.8 11.0 2.7 6.8 11.7 10.1 7.0 21.1 33.9 21.2 29.2 12.7 14.3 13.5 7.7 25.4 10.4 11.2 30.3 3.7 24.8 9.6 3.9 20.2 11.0 4.4 2.5 10.5 14.2 7.3 0.7 20.7 7.5 4.3 22.3 10.2 12.4 1.6 9.0 9.9 9.6 14.0 6.7 11.2 4.3 10.3 4.7 5.2 30.1 3.9 9.4 7.1 12.1 18.3 10.1 12.1 2.9 6.0 9.1 8.4 6.7 8.0 3.5 10.9 7.5 19.2 19.9 18.6 5.9 2.7 34.6 15.2 5.9 8.5 7.4 30.6 9.1 11.2 19.0 6.6 1.3 2.4 8.3 2.8 12.6 0.6 0.7 5.3 0.1 3.5 10.7 13.8 5.6 9.2 8.4 9.5 1.7 10.4 5.4 7.0 4.6 3.9 13.6 8.6 2.4 8.7 2.2 1.6 7.6 3.2 2.8 1.5 0.0 0.0 3.3 0.0 1.9 0.1 1.5 2.9 0.1 0.1 0.5 1.2 0.2 6.9 0.0 0.0 2.0 1.0 23.1 20.8 18.6 42.7 21.1 33.9 13.5 7.7 24.8 0.7 22.3 14.0 6.0 0.0 3.9 5.2 2.8 4.1 2.3 4.9 7.4 161.2 15.7 7.5 2.3 4.3 3.3 14.7 62.6 5.4 14.1 2.9 0.0 9.2 1.2 3.3 18.0 15.3 29.3 1.3 79.4 7.5 9.3 12.0 7.7 6.3 5.7 8.6 5.7 26.6 1.2 26.9 60.2 4.0 16.2 2.0 7.3 1.9 12.8 3.6 5.4 4.7 1.1 9.5 13.4 10.6 3.1 7.2 3.2 6.4 12.7 1.9 1.3 23.3 3.0 40.3 6.6 5.1 6.8 0.7 1.1 2.7 5.7 3.3 16.6 6.8 3.6 1.8 CMIP ENSG00000153815 "C-Maf inducing protein" Q8IY22 16 81444808-81711762 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 3.0;neutrophil: 2.4" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "HMC-1: 180.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054424, HPA066710" Approved Supported Nucleoplasm,Cytosol NA NA 83000 "Cluster 17: Basophils - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" "Nucleoplasm, Cytosol" "HPA054424: AB_2682484, HPA066710: AB_2685708" "unprognostic (6.84e-2)" "unprognostic (1.99e-1)" "unprognostic (2.89e-2)" "unprognostic (3.76e-1)" "unprognostic (3.02e-2)" "unprognostic (9.83e-3)" "unprognostic (2.28e-2)" "prognostic unfavorable (9.47e-7)" "unprognostic (1.60e-1)" "unprognostic (1.64e-1)" "unprognostic (3.10e-2)" "unprognostic (6.04e-2)" "unprognostic (4.12e-2)" "unprognostic (3.42e-2)" "unprognostic (9.08e-2)" "prognostic unfavorable (1.05e-4)" "unprognostic (1.59e-1)" 27.9 22.1 45.2 32.1 46.2 26.1 23.2 12.6 50.1 30.7 0.0 26.5 40.4 18.8 6.1 35.8 23.0 25.6 13.0 48.8 51.1 20.7 13.5 26.3 22.2 29.9 34.8 22.8 19.3 7.8 55.6 28.4 46.1 17.7 23.1 10.8 20.1 15.0 4.7 34.3 49.9 22.5 19.9 22.5 33.3 17.2 52.7 20.1 15.6 5.3 18.2 31.2 32.8 34.4 40.9 133.5 25.9 13.3 13.4 10.7 52.7 28.9 19.5 17.9 7.9 45.5 81.5 18.2 24.2 24.1 23.9 40.6 16.9 96.2 17.0 11.6 12.3 87.4 24.4 80.0 13.3 27.2 180.8 10.5 39.9 33.1 42.5 27.1 50.0 31.7 77.6 15.3 11.1 40.9 47.7 33.8 20.6 39.5 28.1 84.9 8.5 17.8 22.6 39.7 135.0 27.1 67.4 24.7 8.6 25.9 19.1 35.7 34.6 28.5 30.6 27.7 26.8 19.2 15.9 78.0 33.6 31.5 11.7 3.0 0.7 1.0 0.4 0.5 0.2 0.0 0.1 0.1 0.2 0.3 0.0 0.2 2.4 0.2 0.1 0.2 0.1 0.4 45.2 46.2 12.6 50.1 48.8 51.1 29.9 34.8 46.1 19.9 52.7 34.4 81.5 12.8 16.6 59.4 31.7 107.3 66.6 43.8 48.9 15.6 21.5 21.1 7.8 47.1 27.7 14.7 0.0 46.5 71.2 58.0 7.9 22.3 70.0 51.1 9.2 77.3 72.1 17.9 119.1 23.8 106.6 25.7 35.7 45.4 45.1 29.8 70.6 31.6 32.0 25.2 95.2 128.0 40.7 69.4 115.9 100.8 47.5 95.5 12.4 100.2 68.2 8.0 37.0 69.9 52.9 65.5 30.9 143.3 35.2 69.6 47.3 49.6 57.6 3.4 13.1 8.0 24.1 5.0 15.4 51.8 143.5 88.7 42.8 6.4 39.1 111.7 COL17A1 "BP180, BPAG2" ENSG00000065618 "Collagen type XVII alpha 1 chain" Q9UMD9 10 104031286-104085880 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 580.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 585.7;Basal respiratory cells: 136.0;Basal squamous epithelial cells: 299.9;Distal enterocytes: 211.5;Proximal enterocytes: 108.5;Suprabasal keratinocytes: 139.4" "Cancer enriched" "Detected in many" 5 "head and neck cancer: 227.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 204.3;HaCaT: 463.8;HBEC3-KT: 745.8;hTCEpi: 914.1;hTERT-HME1: 783.7" "Region enriched" "Detected in single" 4 "cerebellum: 1.0" "Low region specificity" "Detected in many" "HPA043673, HPA052963" Enhanced Supported "Golgi apparatus,Plasma membrane" "Secreted to extracellular matrix" NA NA 32000 "Cluster 1: Neutrophils - Mixed function" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Golgi apparatus" "HPA043673: AB_10960893, HPA052963: AB_2681999" "prognostic favorable (1.38e-4)" "unprognostic (1.33e-1)" "unprognostic (4.01e-1)" "unprognostic (1.01e-1)" "unprognostic (9.65e-2)" "unprognostic (3.75e-1)" "unprognostic (2.13e-1)" "unprognostic (6.82e-3)" "unprognostic (1.63e-1)" "unprognostic (7.85e-3)" "prognostic unfavorable (1.86e-4)" "unprognostic (2.12e-1)" "unprognostic (1.71e-1)" "unprognostic (1.14e-1)" "unprognostic (1.23e-1)" "unprognostic (3.75e-2)" "unprognostic (8.35e-2)" 1.5 0.4 0.8 6.6 1.1 12.2 37.3 1.0 1.4 50.1 0.6 37.4 10.7 0.6 6.6 116.6 1.1 0.3 0.5 0.5 0.6 0.3 0.3 0.9 0.1 0.6 0.7 0.2 0.4 0.0 1.2 35.4 0.6 17.9 27.3 0.0 82.2 9.6 0.5 580.3 37.2 1.0 0.5 2.3 19.8 25.4 0.6 42.7 5.1 0.0 19.8 9.9 102.0 0.8 26.3 0.4 1.5 0.2 0.1 0.0 80.6 0.5 0.3 0.1 0.2 0.3 204.3 0.0 5.1 0.3 3.9 463.8 0.7 745.8 0.7 0.0 0.7 0.0 0.3 0.2 0.1 0.0 0.4 0.7 914.1 0.5 783.7 0.2 3.5 0.1 0.1 0.9 0.0 0.0 0.0 0.3 1.7 5.1 2.6 0.0 0.0 0.3 35.9 26.4 0.2 0.3 0.0 0.2 0.9 4.0 0.2 0.0 1.5 0.5 5.0 0.3 5.5 0.1 0.0 0.0 1.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.8 1.1 1.0 1.4 0.5 0.6 0.6 0.7 0.6 0.5 0.6 0.8 1.0 0.0 1.1 0.7 0.3 585.7 17.7 136.0 299.9 0.6 1.7 85.5 1.1 0.0 16.5 0.0 0.0 10.2 0.3 211.5 0.0 0.8 14.2 23.7 2.3 3.7 2.4 0.0 0.1 0.9 18.9 2.4 23.0 8.1 0.0 0.1 0.0 0.0 1.3 0.0 0.2 5.7 6.1 0.0 28.9 3.6 0.3 0.7 33.8 0.0 0.0 0.4 0.0 0.0 0.4 78.8 35.7 0.7 1.4 16.6 108.5 0.1 5.9 0.4 0.0 0.4 3.0 22.7 1.5 31.9 139.4 5.6 1.3 0.1 21.6 10.7 COL1A2 OI4 ENSG00000164692 "Collagen type I alpha 2 chain" P08123 7 94394895-94431227 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Dwarfism, Ehlers-Danlos syndrome, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 1831.7;gallbladder: 1378.0;smooth muscle: 1416.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 774.5;Fibroblasts: 2148.2;Glandular and luminal cells: 592.2;Leydig cells: 991.9;Peritubular cells: 501.0;Smooth muscle cells: 770.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 3899.2;ASC TERT1: 4637.0;BJ: 3995.6;BJ hTERT+: 2901.2;fHDF/TERT166: 13615.1;HSkMC: 4058.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 133.7" "CAB032650, HPA059738" Approved Supported "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 27000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "CAB032650: AB_2082039, HPA059738: AB_2684116" "unprognostic (1.20e-1)" "unprognostic (6.34e-2)" "unprognostic (1.32e-1)" "unprognostic (3.40e-2)" "unprognostic (2.86e-2)" "unprognostic (2.81e-1)" "unprognostic (5.15e-2)" "unprognostic (7.38e-3)" "unprognostic (2.01e-2)" "unprognostic (1.40e-2)" "unprognostic (5.83e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (1.51e-9)" "unprognostic (1.35e-2)" "unprognostic (5.25e-2)" "unprognostic (1.15e-1)" "unprognostic (3.31e-3)" 514.8 52.4 6.8 266.2 9.3 2.0 314.5 7.1 17.4 1831.7 18.1 175.7 61.1 411.2 61.6 263.2 206.6 1378.0 275.4 6.0 6.8 40.8 27.4 229.5 91.6 8.7 6.7 297.2 57.1 32.5 33.5 624.6 7.9 196.2 141.8 1.6 60.2 232.3 51.6 424.6 103.2 1416.9 8.8 69.3 89.1 136.6 15.6 32.8 86.4 102.1 60.1 805.6 295.2 8.2 0.1 0.0 22.8 1488.5 3899.2 4637.0 1.3 3995.6 2901.2 642.6 850.5 0.0 2.8 0.3 2.7 13615.1 0.0 0.6 2.2 1.5 160.9 0.1 0.2 0.1 0.0 0.0 1018.6 1.1 0.5 4058.4 0.1 507.9 2.4 0.3 0.5 0.0 0.3 0.3 551.0 0.0 0.6 1.5 2.5 0.0 6.3 0.5 0.8 0.8 0.1 0.0 12.9 1.4 0.3 1.0 0.1 296.0 2.1 0.1 15.9 1626.3 0.8 1022.7 115.5 1.2 0.1 0.4 408.6 0.5 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 9.3 7.1 17.4 6.0 6.8 8.7 6.7 7.9 8.8 15.6 8.2 112.9 3.2 12.9 1.0 0.8 223.1 0.7 9.3 4.6 0.2 7.2 8.6 21.7 0.0 3.3 1.8 0.0 31.5 2.5 0.0 0.0 3.0 8.4 183.2 774.5 57.2 0.0 0.0 0.0 0.2 31.7 2148.2 26.5 592.2 10.1 16.4 258.8 1.9 116.9 0.0 0.1 0.0 0.0 1.0 394.5 45.1 991.9 16.7 238.3 97.4 2.6 3.2 0.0 0.0 0.2 5.2 0.0 501.0 4.5 1.0 0.0 0.5 0.8 0.4 302.4 249.9 770.7 9.9 4.5 6.2 187.4 70.7 30.6 214.8 0.0 0.8 COPZ2 MGC23008 ENSG00000005243 "COPI coat complex subunit zeta 2" Q9P299 17 48026167-48038030 "Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 49.8;Endometrial stromal cells: 63.8;Fibroblasts: 77.7;Leydig cells: 50.4;Smooth muscle cells: 49.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 167.4;ASC TERT1: 185.6;BJ: 127.1;BJ hTERT+: 133.1;fHDF/TERT166: 271.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055999 Uncertain NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA055999: AB_2683003" "unprognostic (2.66e-1)" "unprognostic (9.32e-2)" "unprognostic (2.18e-2)" "unprognostic (1.46e-1)" "unprognostic (6.28e-2)" "unprognostic (1.12e-1)" "unprognostic (2.77e-2)" "unprognostic (1.59e-1)" "unprognostic (9.34e-2)" "unprognostic (2.49e-1)" "unprognostic (7.02e-2)" "unprognostic (9.65e-2)" "prognostic unfavorable (3.45e-9)" "unprognostic (7.42e-3)" "unprognostic (2.76e-2)" "prognostic unfavorable (2.89e-6)" "prognostic unfavorable (4.66e-4)" 71.7 28.6 11.8 11.7 12.6 1.0 46.4 13.0 19.1 41.8 22.8 57.0 6.2 38.3 21.4 15.9 32.6 22.9 57.1 12.4 16.4 19.2 33.2 22.1 5.8 15.3 12.5 13.6 19.7 24.3 14.8 22.5 15.1 34.2 14.7 5.1 23.4 36.8 90.8 35.3 18.2 45.6 14.0 11.7 27.1 11.6 13.1 4.9 32.1 48.6 6.9 37.3 33.1 15.7 38.7 7.5 4.1 0.0 167.4 185.6 0.0 127.1 133.1 35.0 38.6 0.0 4.4 0.0 28.3 271.6 0.0 39.5 0.0 0.5 34.9 1.7 0.1 13.6 21.3 0.1 68.4 0.0 0.8 111.7 16.0 26.2 3.5 41.1 5.3 0.3 0.1 0.8 86.9 18.1 0.4 0.0 0.2 2.6 2.5 0.0 0.0 6.1 2.4 0.0 0.2 5.7 24.6 0.0 28.3 1.0 6.0 4.2 34.4 91.5 14.5 72.9 0.5 91.6 11.1 1.3 99.3 0.0 13.1 0.0 0.5 0.0 0.3 0.4 0.0 0.0 0.1 0.5 0.1 0.0 0.0 0.4 0.0 0.1 0.2 0.0 0.0 0.1 11.8 12.6 13.0 19.1 12.4 16.4 15.3 12.5 15.1 14.0 13.1 15.7 31.6 9.6 2.2 8.1 2.6 49.8 16.7 9.4 9.1 1.2 7.3 30.1 37.1 0.0 1.4 7.3 0.0 1.0 7.5 0.4 11.7 1.0 7.0 2.1 63.8 15.6 0.0 0.0 1.4 5.1 1.2 77.7 0.0 1.5 1.3 2.7 16.4 39.0 6.9 0.0 1.7 2.3 2.0 4.4 28.4 21.1 50.4 3.4 28.4 7.5 0.8 34.8 4.1 2.5 7.6 2.5 0.0 41.8 3.5 6.0 0.1 19.1 0.6 1.3 6.6 21.6 49.2 14.1 3.7 3.1 26.0 2.3 3.7 8.5 0.4 11.7 CPLX1 CPX-I ENSG00000168993 "Complexin 1" O14810 4 784957-826129 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Exocytosis, Neurotransmitter transport, Transport" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "brain: 273.5" "Cell type enhanced" "Detected in many" "Adipocytes: 45.5;Bipolar cells: 33.4;Endothelial cells: 29.6;Excitatory neurons: 44.2;Inhibitory neurons: 90.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "SCLC-21H: 84.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA071191, HPA074390" Supported Uncertain Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 65: Brain - Ion transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA071191: , HPA074390: " "unprognostic (9.21e-3)" "prognostic unfavorable (4.20e-4)" "unprognostic (3.45e-2)" "unprognostic (4.68e-2)" "unprognostic (1.16e-2)" "unprognostic (1.02e-1)" "unprognostic (3.14e-2)" "unprognostic (2.26e-2)" "unprognostic (9.52e-3)" "unprognostic (2.01e-2)" "prognostic favorable (5.05e-4)" "unprognostic (1.10e-3)" "unprognostic (3.32e-1)" "unprognostic (2.05e-2)" "unprognostic (1.12e-1)" "unprognostic (1.34e-1)" "unprognostic (7.77e-2)" 17.2 13.4 26.1 1.2 43.0 0.1 18.2 59.7 273.5 16.9 0.0 5.0 1.0 10.8 0.1 5.7 16.4 0.4 11.5 18.5 72.8 10.9 8.3 9.4 0.8 135.5 25.1 9.4 3.2 1.4 12.8 0.3 128.2 13.8 0.2 5.7 9.6 0.7 4.1 3.4 5.1 0.4 13.9 27.2 4.9 8.6 124.2 3.6 7.5 0.2 0.2 8.3 12.9 89.9 5.7 0.5 0.1 0.8 0.0 0.0 0.3 0.2 0.0 0.0 0.0 16.3 1.7 4.2 1.9 0.0 0.3 0.0 0.4 0.0 0.0 0.0 1.8 0.4 0.0 1.8 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 2.3 2.0 0.3 0.0 2.5 2.3 0.0 2.6 4.4 2.6 0.1 0.0 1.6 0.0 0.4 84.3 11.8 0.4 5.5 0.0 0.2 8.5 0.3 0.1 0.0 0.5 0.1 0.1 0.2 4.7 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 26.1 43.0 59.7 273.5 18.5 72.8 135.5 25.1 128.2 13.9 124.2 89.9 45.5 0.0 0.0 5.9 0.4 1.0 3.2 0.4 1.8 33.4 7.8 8.1 3.6 0.0 1.9 0.0 4.2 0.1 2.8 2.5 1.9 1.2 1.4 1.1 5.4 29.6 21.5 0.0 44.2 0.8 3.2 1.8 2.6 1.4 0.0 0.3 14.3 4.8 0.2 18.5 90.7 2.1 0.0 0.3 1.9 2.3 1.8 0.5 1.8 8.4 0.0 16.8 0.0 8.0 4.7 0.8 5.2 0.0 0.6 2.6 0.3 1.2 0.0 21.7 0.0 0.4 2.3 4.3 9.8 0.2 1.1 1.0 1.6 0.8 2.7 1.3 CPM ENSG00000135678 "Carboxypeptidase M" P14384 12 68842197-68971570 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 156.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 359.0;Alveolar cells type 2: 362.2;Kupffer cells: 368.5;Sertoli cells: 762.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 21.0;intermediate monocyte: 14.5;myeloid DC: 16.6;non-classical monocyte: 7.4" "Group enriched" "Detected in many" 5 "dendritic cells: 16.6;monocytes: 21.0" "Group enriched" "Detected in many" 4 "ASC diff: 71.1;ASC TERT1: 50.0;HSkMC: 91.2;SiHa: 68.9;THP-1: 26.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002657, HPA077243" Enhanced Uncertain Vesicles NA NA 7100000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA002657: AB_1078398, HPA077243: " "unprognostic (1.74e-1)" "unprognostic (3.11e-1)" "unprognostic (2.88e-3)" "prognostic favorable (1.00e-4)" "unprognostic (4.58e-2)" "unprognostic (8.61e-2)" "unprognostic (1.57e-2)" "unprognostic (2.01e-1)" "unprognostic (8.42e-2)" "unprognostic (1.40e-1)" "unprognostic (1.35e-1)" "unprognostic (1.42e-1)" "unprognostic (1.47e-3)" "unprognostic (8.58e-2)" "unprognostic (6.85e-2)" "unprognostic (2.59e-2)" "unprognostic (1.06e-1)" 156.1 11.5 6.4 14.4 13.3 3.5 40.2 10.1 10.5 14.4 3.8 33.5 4.4 23.9 0.9 10.1 16.2 16.1 4.6 7.6 10.2 41.3 26.5 59.3 16.1 19.3 11.5 18.0 13.0 12.0 1.0 70.1 11.9 14.7 26.6 6.7 4.1 2.8 5.8 21.7 5.9 6.4 7.5 19.4 15.3 5.4 28.0 4.3 7.5 9.7 10.5 9.3 5.7 23.5 0.1 4.0 0.1 0.0 71.1 50.0 0.7 9.8 1.1 1.7 2.3 3.2 4.1 0.5 9.6 1.4 4.1 0.0 1.4 2.7 4.1 0.1 2.7 0.0 15.1 0.3 0.4 1.2 1.9 91.2 0.6 1.0 2.0 8.6 0.0 0.3 0.0 0.1 7.3 1.7 0.0 0.7 1.7 0.0 5.2 3.1 0.6 0.0 7.2 5.9 0.4 0.2 68.9 10.7 7.9 5.5 1.2 26.5 0.2 1.2 7.5 0.5 0.2 0.4 0.5 13.1 4.3 13.1 5.9 0.6 21.0 0.1 0.2 14.5 0.0 1.8 1.5 0.1 16.6 3.5 0.9 0.2 1.6 0.5 7.4 1.1 1.9 7.3 6.4 13.3 10.1 10.5 7.6 10.2 19.3 11.5 11.9 7.5 28.0 23.5 83.3 359.0 362.2 34.6 4.9 12.4 3.5 6.1 0.6 3.3 7.8 8.9 2.6 135.8 70.1 51.5 0.0 32.3 1.1 97.5 29.4 57.9 16.6 100.9 8.3 29.0 10.8 3.6 1.2 212.5 59.9 14.1 4.6 237.1 112.5 6.7 73.9 36.6 134.6 0.0 1.3 28.7 0.0 368.5 36.3 17.5 105.0 202.2 10.6 19.7 23.3 68.9 1.0 23.1 161.8 68.0 65.9 79.0 2.4 38.7 1.9 63.7 16.4 5.7 762.6 7.2 126.9 0.6 3.9 2.4 9.9 172.4 14.5 46.3 32.7 2.8 CRACR2B "EFCAB4A, MGC45840" ENSG00000177685 "Calcium release activated channel regulator 2B" Q8N4Y2 11 826144-831991 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 208.7;salivary gland: 223.6" "Cell type enhanced" "Detected in many" "Breast glandular cells: 180.4;Breast myoepithelial cells: 116.3;Gastric mucus-secreting cells: 178.9;Hepatic stellate cells: 85.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 3.4;eosinophil: 3.7;memory B-cell: 3.9;naive B-cell: 3.0;NK-cell: 1.7" "Group enriched" "Detected in many" 6 "B-cells: 3.9;granulocytes: 3.7;NK-cells: 1.7" "Cell line enhanced" "Detected in many" "NB-4: 35.2;OE19: 29.6;SK-BR-3: 111.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046217 Approved NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 25: Pancreas - Digestion" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 35: Glandular cells - Unknown function" "HPA046217: AB_10960833" "unprognostic (8.87e-2)" "unprognostic (4.89e-2)" "prognostic unfavorable (1.81e-5)" "unprognostic (4.47e-3)" "unprognostic (8.20e-3)" "unprognostic (5.27e-3)" "unprognostic (7.31e-2)" "unprognostic (1.90e-2)" "unprognostic (1.63e-1)" "unprognostic (5.61e-3)" "unprognostic (3.49e-3)" "unprognostic (9.25e-3)" "unprognostic (5.28e-2)" "unprognostic (4.29e-3)" "unprognostic (3.03e-1)" "unprognostic (3.65e-1)" "unprognostic (5.15e-3)" 11.9 8.4 1.5 3.3 1.6 13.3 65.8 3.1 2.1 8.3 3.5 43.6 22.4 4.6 1.0 6.7 6.4 6.8 22.4 1.3 1.5 27.0 3.4 14.9 2.4 1.8 1.5 1.3 208.7 6.8 23.3 2.7 1.8 44.9 13.6 1.0 223.6 5.2 4.3 21.9 28.5 1.2 1.1 13.9 81.0 2.4 1.9 0.6 6.4 1.7 2.0 19.6 3.9 1.0 3.6 3.1 0.6 1.5 0.2 0.0 11.5 0.3 0.0 0.1 0.0 3.8 12.0 0.0 4.7 0.0 0.3 3.2 2.1 0.1 0.0 26.2 1.1 13.3 3.1 8.8 0.0 10.9 0.5 0.2 0.5 0.0 0.0 2.2 0.5 1.4 17.3 10.7 0.0 8.0 0.3 35.2 0.9 29.6 0.4 2.4 0.6 22.5 8.7 2.8 2.8 1.5 0.4 111.6 0.0 0.6 17.5 9.0 0.3 1.7 0.6 0.4 0.2 26.3 2.4 3.8 5.5 14.4 0.1 3.4 0.5 3.7 0.1 0.0 0.0 3.9 0.0 0.3 0.0 3.0 0.0 0.0 0.1 1.7 0.3 0.5 0.0 0.2 1.5 1.6 3.1 2.1 1.3 1.5 1.8 1.5 1.8 1.1 1.9 1.0 61.5 6.4 19.8 3.3 16.8 0.0 6.6 0.0 1.8 2.4 180.4 116.3 8.8 22.8 27.2 12.9 0.0 3.8 6.4 18.8 15.6 15.0 2.6 11.6 1.9 34.8 12.2 6.1 0.1 37.1 1.7 2.5 178.9 16.2 1.3 0.6 85.3 2.0 3.5 0.0 0.1 71.9 0.0 5.0 0.0 5.0 2.5 3.8 0.0 3.7 1.2 11.4 0.0 0.0 0.0 25.8 40.5 1.9 24.2 29.6 46.2 4.3 13.1 7.2 13.1 2.4 4.4 2.1 6.5 4.2 0.0 1.8 5.0 1.8 43.6 66.5 CRAT CAT1 ENSG00000095321 "Carnitine O-acetyltransferase" P43155 9 129094142-129111189 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Fatty acid metabolism, Lipid metabolism, Transport" "Acyltransferase, Transferase" Neurodegeneration "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 227.5;tongue: 201.3" "Cell type enhanced" "Detected in many" "Early spermatids: 181.2;Late spermatids: 521.8;Proximal enterocytes: 136.4;Spermatocytes: 123.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019230, HPA020260, HPA022815" Enhanced Approved "Nucleoplasm,Nuclear membrane" NA NA 8100 "Cluster 39: Non-specific - mRNA processing" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 6: T47d - Mammary gland" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Nuclear membrane" "HPA019230: AB_1847212, HPA020260: AB_1847210, HPA022815: AB_2732427" "unprognostic (5.13e-2)" "unprognostic (9.79e-3)" "unprognostic (1.99e-2)" "prognostic favorable (2.36e-4)" "unprognostic (2.19e-1)" "unprognostic (1.14e-1)" "unprognostic (1.15e-2)" "unprognostic (2.18e-1)" "unprognostic (5.11e-2)" "unprognostic (3.24e-2)" "unprognostic (3.13e-3)" "unprognostic (2.03e-1)" "prognostic favorable (0.00e+0)" "unprognostic (1.38e-1)" "unprognostic (9.27e-2)" "unprognostic (1.26e-2)" "unprognostic (7.65e-2)" 36.1 51.3 26.4 5.4 26.6 9.0 29.2 27.0 33.8 31.7 27.5 36.1 33.0 24.8 4.0 37.3 23.1 6.6 68.2 25.1 27.8 46.9 151.2 15.2 3.2 28.8 28.2 23.0 107.1 26.3 12.3 6.6 30.6 42.2 4.2 1.7 32.8 8.9 227.5 29.6 37.2 6.8 26.7 15.2 34.0 146.4 30.2 3.1 21.5 201.3 1.6 31.3 27.5 24.4 0.1 39.3 10.7 21.3 13.4 25.9 17.0 15.0 16.6 18.9 12.0 7.8 14.0 1.5 9.2 25.9 23.2 6.7 2.2 4.9 7.2 23.6 0.3 7.3 19.1 30.4 34.1 0.0 26.1 26.3 0.0 15.7 0.9 15.8 26.2 7.2 3.6 5.7 20.0 9.1 0.5 15.9 2.8 32.0 18.0 16.8 21.8 12.2 18.0 0.6 4.2 12.1 0.0 7.1 4.8 3.4 49.7 5.5 22.6 23.0 1.6 32.1 15.4 25.5 22.6 0.1 28.8 4.2 16.8 1.6 8.4 3.5 3.2 5.5 6.7 1.5 4.4 4.3 8.6 1.3 2.6 3.1 1.1 4.4 5.6 3.9 4.5 6.1 26.4 26.6 27.0 33.8 25.1 27.8 28.8 28.2 30.6 26.7 30.2 24.4 10.5 6.4 3.7 5.5 4.9 3.2 4.7 10.8 0.6 1.5 9.7 8.1 57.8 21.5 8.2 3.7 2.1 45.9 6.0 64.5 17.6 22.6 181.2 3.5 15.7 12.9 15.5 17.4 5.3 22.4 55.6 19.3 16.8 9.9 7.0 12.9 14.6 65.7 20.7 1.7 6.1 23.6 14.2 13.9 10.5 521.8 22.1 12.4 5.4 6.5 8.3 15.5 6.2 3.5 4.0 11.6 47.6 24.5 9.6 9.3 136.4 52.0 2.8 1.3 6.6 10.5 15.7 123.5 8.6 57.4 4.5 50.3 7.6 20.1 29.3 13.8 CRISP2 "CRISP-2, CT36, GAPDL5, TPX1" ENSG00000124490 "Cysteine rich secretory protein 2" P16562 6 49692358-49713590 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 29 "testis: 505.0" "Group enriched" "Detected in some" 33 "Early spermatids: 5765.5;Late spermatids: 21517.6" "Cancer enhanced" "Detected in some" "pancreatic cancer: 1.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA031248 Enhanced "Secreted in male reproductive system" NA NA 820000 "Cluster 83: Testis - Spermatogenesis" "Cluster 25: Spermatids - Spermatogenesis" "HPA031248: AB_10602211" "unprognostic (1.10e-1)" "unprognostic (1.51e-1)" "unprognostic (1.72e-2)" "unprognostic (7.38e-2)" "unprognostic (2.35e-2)" "unprognostic (9.23e-3)" "unprognostic (4.05e-2)" 0.1 0.0 0.0 0.0 0.0 16.6 0.5 0.0 0.0 1.9 0.7 0.0 0.1 0.2 0.9 3.6 17.6 7.7 0.1 0.0 0.2 0.8 0.2 1.2 0.0 0.1 0.1 0.1 0.6 0.0 2.0 0.0 0.0 1.2 0.0 0.1 15.6 2.5 0.2 0.5 0.3 0.0 0.0 0.5 0.1 505.0 0.1 0.0 0.2 0.0 0.0 0.1 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.6 0.3 0.1 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 5765.5 17.8 0.5 6.3 0.0 0.0 0.0 0.2 0.0 0.1 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 21517.6 133.9 6.1 5.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 83.8 0.0 2.8 0.2 0.1 24.1 0.0 65.7 0.0 0.0 409.8 65.1 0.0 0.0 0.0 0.0 0.0 0.3 2.3 CRISP3 "Aeg2, CRISP-3, CRS3, dJ442L6.3, SGP28" ENSG00000096006 "Cysteine rich secretory protein 3" P54108 6 49727376-49744437 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "fallopian tube: 1203.8;salivary gland: 2310.0" "Group enriched" "Detected in some" 7 "Endometrial ciliated cells: 182.2;Glandular and luminal cells: 551.5" "Group enriched" "Detected in many" 7 "breast cancer: 31.9;pancreatic cancer: 59.8;prostate cancer: 85.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 19 "neutrophil: 2.5;non-classical monocyte: 1.2" "Group enriched" "Detected in many" 19 "granulocytes: 2.5;monocytes: 1.2" "Group enriched" "Detected in some" 20 "HEL: 12.3;RT4: 4.1;SK-BR-3: 9.3;T-47d: 4.4" "Not detected" "Not detected" HPA054392 Supported "Secreted in other tissues" NA NA 420000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 36: HEL - Hemostasis" "Cluster 44: Endometrium - Transcription" "HPA054392: AB_2682472" "unprognostic (1.28e-2)" "unprognostic (7.01e-2)" "unprognostic (8.93e-2)" "unprognostic (5.56e-2)" "unprognostic (1.02e-1)" "unprognostic (2.22e-4)" "unprognostic (5.30e-2)" "unprognostic (6.70e-2)" "unprognostic (9.16e-2)" "unprognostic (4.34e-3)" "unprognostic (1.91e-1)" "unprognostic (1.93e-1)" 0.3 0.6 0.0 0.0 0.0 381.8 3.9 0.0 0.0 61.0 0.0 0.1 0.4 1.7 0.1 266.8 1203.8 23.1 0.8 0.0 0.0 0.1 0.9 1.3 0.0 0.0 0.0 0.5 5.5 0.0 0.5 0.6 0.0 2.9 0.0 0.0 2310.0 111.9 0.3 3.9 0.2 0.0 0.0 2.5 0.3 0.2 0.0 0.3 0.2 0.0 4.0 4.7 140.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 9.3 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 1.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 1.0 0.0 0.0 0.0 2.1 5.6 0.0 21.5 13.1 3.7 0.0 0.0 0.0 0.0 0.0 1.5 0.0 182.2 47.2 0.8 0.0 0.4 0.0 3.7 0.0 0.2 0.0 551.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 23.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 1.5 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 1.7 0.1 0.0 26.8 CSF1R "C-FMS, CD115, CSFR, FMS" ENSG00000182578 "Colony stimulating factor 1 receptor" P07333 5 150053291-150113372 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Immunity, Inflammatory response, Innate immunity" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Neurodegeneration, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 113.3;placenta: 103.3" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 103.2;Hofbauer cells: 340.4;Kupffer cells: 291.2;Langerhans cells: 73.4;Macrophages: 196.3;Microglial cells: 134.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 444.6;non-classical monocyte: 646.9" "Lineage enriched" "Detected in many" 5 "monocytes: 646.9" "Group enriched" "Detected in some" 4 "BEWO: 123.0;SK-BR-3: 47.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008970, HPA012323" Uncertain Supported "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 1600000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 4: Macrophages - Innate immune response" "Vesicles, Plasma membrane" "CAB008970: , HPA012323: AB_1848977" "unprognostic (3.82e-2)" "unprognostic (1.31e-1)" "unprognostic (1.86e-3)" "unprognostic (9.83e-2)" "unprognostic (1.20e-1)" "unprognostic (7.33e-2)" "unprognostic (1.03e-1)" "unprognostic (1.45e-1)" "unprognostic (9.37e-2)" "unprognostic (1.11e-2)" "unprognostic (2.49e-1)" "unprognostic (1.65e-1)" "prognostic unfavorable (1.08e-4)" "unprognostic (3.67e-2)" "prognostic unfavorable (4.92e-4)" "unprognostic (1.72e-2)" "unprognostic (4.61e-2)" 51.3 31.0 19.6 75.1 17.1 5.6 19.3 20.2 21.4 21.6 19.3 21.9 24.3 12.1 5.8 21.0 17.2 40.6 16.6 19.8 33.8 7.1 27.5 36.6 54.4 41.4 35.5 12.7 9.9 11.8 5.7 103.3 40.1 9.1 21.5 1.5 10.1 20.8 3.2 13.4 37.3 41.9 36.6 113.3 21.0 7.0 40.6 14.3 6.0 11.8 21.7 42.6 3.8 67.6 4.5 0.2 0.0 0.0 1.9 0.4 123.0 0.2 0.2 0.0 0.0 3.8 0.0 5.9 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.2 1.1 3.0 0.0 6.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 6.1 0.1 0.0 0.0 0.0 1.9 0.6 0.0 0.0 0.2 0.2 0.0 47.8 0.0 1.9 0.0 20.7 0.0 0.8 0.2 0.1 3.3 0.0 0.3 0.1 6.6 2.6 0.0 3.0 138.4 4.0 0.6 444.6 0.6 0.3 0.2 0.4 139.0 0.2 0.3 0.2 21.6 0.2 646.9 11.1 0.5 132.7 19.6 17.1 20.2 21.4 19.8 33.8 41.4 35.5 40.1 36.6 40.6 67.6 2.0 0.0 3.8 0.0 4.3 2.8 0.0 0.0 1.2 0.0 0.5 2.3 3.1 4.3 0.0 0.0 0.0 6.2 2.8 0.0 0.0 0.0 4.8 0.0 0.1 10.5 0.0 2.5 0.4 0.0 103.2 2.2 1.5 0.2 2.5 8.3 2.9 1.5 340.4 0.0 0.5 0.3 0.0 291.2 73.4 5.4 1.8 196.3 3.6 134.9 39.4 0.0 1.0 1.5 0.3 0.1 1.7 0.0 1.0 0.0 0.0 0.1 0.7 0.5 13.1 1.2 2.0 2.2 0.2 0.4 1.3 26.4 1.3 2.2 0.2 0.0 CST3 ENSG00000101439 "Cystatin C" P01034 20 23626706-23638473 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Age-related macular degeneration, Amyloidosis, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 4217.6" "Cell type enriched" "Detected in all" 4 "Langerhans cells: 18746.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "classical monocyte: 4967.5;intermediate monocyte: 6424.5;myeloid DC: 7959.0;non-classical monocyte: 4297.7;plasmacytoid DC: 4427.4" "Group enriched" "Detected in all" 9 "dendritic cells: 7959.0;monocytes: 6424.5" "Cell line enhanced" "Detected in many" "ASC diff: 1733.4;ASC TERT1: 1179.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000118, HPA013143" Enhanced Supported "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 1040000000 2800000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 41: Macrophages - Immune response" "Golgi apparatus, Vesicles" "CAB000118: , HPA013143: AB_1847417" "unprognostic (3.89e-2)" "unprognostic (1.63e-1)" "unprognostic (1.45e-1)" "prognostic favorable (1.83e-4)" "unprognostic (8.53e-2)" "unprognostic (4.06e-2)" "unprognostic (2.10e-2)" "unprognostic (2.18e-2)" "unprognostic (3.46e-2)" "unprognostic (3.72e-1)" "unprognostic (2.29e-3)" "unprognostic (3.51e-2)" "unprognostic (1.85e-1)" "unprognostic (1.16e-1)" "unprognostic (2.97e-1)" "unprognostic (5.01e-2)" "prognostic favorable (8.77e-4)" 1046.2 707.6 3041.2 262.3 3117.9 170.8 900.3 2823.3 4217.6 587.8 3094.8 788.7 389.6 708.3 875.9 557.1 802.7 583.0 1275.3 2976.3 2707.6 517.4 833.6 595.8 463.5 3258.4 3096.2 575.8 944.1 320.0 670.1 165.9 2939.3 773.9 416.9 46.9 2008.0 441.5 749.0 497.1 800.3 367.6 3028.1 723.7 979.9 761.3 3302.7 418.9 658.8 517.4 208.1 703.0 618.4 2883.1 155.2 328.2 75.4 175.8 1733.4 1179.8 145.3 261.4 350.7 170.3 137.7 625.1 219.7 0.8 241.0 345.2 221.3 496.2 69.6 499.9 51.9 0.9 253.5 157.6 61.1 1082.9 621.2 7.5 251.0 919.0 415.9 226.6 241.5 352.5 268.5 18.5 147.6 4.0 239.5 234.4 1.5 162.2 103.5 461.9 752.2 5.7 96.4 215.2 708.0 328.3 84.7 98.2 191.1 54.6 343.3 107.7 156.5 548.2 702.0 163.4 119.0 231.6 97.7 157.1 6.2 1.8 138.0 339.5 184.0 48.1 4967.5 33.2 66.9 6424.5 25.5 23.1 18.3 45.8 7959.0 13.6 16.9 31.1 809.3 191.4 4297.7 4427.4 13.6 4250.8 3041.2 3117.9 2823.3 4217.6 2976.3 2707.6 3258.4 3096.2 2939.3 3028.1 3302.7 2883.1 662.4 115.4 168.8 849.5 93.8 942.9 571.1 568.2 213.9 152.4 660.2 512.1 240.7 1361.2 514.5 641.9 29.2 476.8 603.3 1889.9 414.8 489.9 46.2 441.1 795.0 728.2 882.1 252.1 4.5 783.6 308.7 3026.2 981.7 631.0 359.9 687.0 491.9 2563.0 1816.7 48.8 11.2 1360.6 691.7 4301.1 18746.6 184.3 2132.6 4542.6 1563.5 87.1 2025.6 248.7 99.9 263.9 6.0 1458.5 2342.1 1790.4 67.9 786.0 4301.1 1098.6 364.4 36.3 2195.7 1417.0 846.2 125.5 400.6 461.5 822.0 469.0 117.4 208.1 1039.4 1079.7 CSTA "STF1, STFA" ENSG00000121552 "Cystatin A" P01040 3 122325248-122341969 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Protease inhibitor, Thiol protease inhibitor" "Cancer-related genes, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 5912.9;vagina: 1853.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 2493.8;Club cells: 768.0;Kupffer cells: 579.4;monocytes: 1298.6;Squamous epithelial cells: 3020.6" "Cancer enhanced" "Detected in all" "cervical cancer: 227.7;head and neck cancer: 405.0" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 19 "classical monocyte: 514.7;intermediate monocyte: 269.1;myeloid DC: 382.9;neutrophil: 245.6;non-classical monocyte: 161.7" "Group enriched" "Detected in all" 193 "dendritic cells: 382.9;granulocytes: 245.6;monocytes: 514.7" "Cell line enhanced" "Detected in many" "HBEC3-KT: 282.0;hTCEpi: 1218.6;THP-1: 789.0;U-698: 504.5;U-937: 250.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000469, HPA001031, CAB047315" Enhanced Approved Nucleoplasm,Cytosol No No 28000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoplasm, Cytosol" "CAB000469: , CAB047315: , HPA001031: AB_1078610" "unprognostic (5.22e-3)" "unprognostic (6.10e-2)" "unprognostic (2.64e-1)" "unprognostic (6.07e-2)" "unprognostic (7.79e-3)" "prognostic favorable (5.86e-4)" "unprognostic (4.46e-1)" "unprognostic (1.63e-1)" "unprognostic (1.78e-1)" "unprognostic (7.99e-2)" "unprognostic (2.56e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (2.60e-6)" "unprognostic (8.89e-2)" "unprognostic (3.43e-2)" "unprognostic (9.24e-3)" "unprognostic (1.99e-1)" 30.7 4.7 0.8 27.1 0.9 297.8 56.3 1.0 3.7 961.0 1.4 3.8 1.1 2.2 10.3 5912.9 4.6 7.2 5.9 0.8 1.0 2.4 38.9 26.0 25.1 1.5 0.9 21.1 3.7 0.8 5.0 19.0 1.3 19.7 3.6 0.3 996.1 9.6 4.6 369.1 5.8 6.3 1.1 20.4 30.3 1.3 1.4 46.5 2.7 2.8 941.0 39.1 1853.3 1.6 14.6 1.3 0.2 3.2 31.5 58.0 2.9 0.6 0.8 0.0 0.0 0.0 0.0 3.2 7.6 5.9 0.5 86.9 0.0 282.0 0.0 0.3 0.2 0.7 0.0 6.8 6.8 117.6 1.9 30.5 1218.6 2.9 119.1 0.0 0.0 1.5 0.8 29.9 0.5 0.8 0.2 108.3 0.0 0.5 0.0 0.0 0.9 0.0 0.0 141.3 0.0 0.0 14.1 7.5 10.4 0.1 1.6 789.0 0.5 1.7 19.7 0.2 0.9 0.0 1.7 504.5 26.4 250.3 0.3 8.8 514.7 16.4 0.6 269.1 1.5 1.5 0.7 0.6 382.9 0.5 0.5 0.7 245.6 1.9 161.7 6.9 1.0 283.2 0.8 0.9 1.0 3.7 0.8 1.0 1.5 0.9 1.3 1.1 1.4 1.6 1.1 6.4 19.8 0.0 5.0 83.5 136.5 2493.8 117.8 0.0 7.1 119.8 0.2 2.8 768.0 0.0 0.0 230.6 7.4 3.9 0.0 2.1 0.4 0.3 0.4 3.0 0.0 3.8 0.1 22.1 17.8 13.6 12.8 0.3 13.9 0.1 6.1 96.0 134.5 0.0 0.1 0.5 179.0 579.4 90.6 2.4 10.2 243.7 8.8 0.0 1298.6 0.0 20.6 0.5 0.2 46.2 1.5 3.8 2.8 30.2 0.0 0.7 115.7 0.0 32.9 8.8 24.3 0.1 0.5 3020.6 205.0 334.2 4.9 26.1 2.0 134.1 CTBP2 ribeye ENSG00000175029 "C-terminal binding protein 2" P56545 10 124984317-125161170 "Plasma proteins, Predicted intracellular proteins" "Differentiation, Host-virus interaction, Transcription, Transcription regulation" "Oxidoreductase, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023559, HPA023564, CAB031916, HPA044971, CAB079018" Approved Approved Approved Nucleoplasm NA NA 10000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" Nucleoplasm "CAB031916: AB_2086774, CAB079018: , HPA023559: AB_1847309, HPA023564: AB_1847310, HPA044971: AB_2679161" "unprognostic (8.69e-2)" "unprognostic (1.27e-2)" "unprognostic (4.14e-2)" "unprognostic (1.41e-2)" "unprognostic (6.84e-3)" "unprognostic (4.05e-3)" "unprognostic (3.63e-2)" "unprognostic (5.60e-3)" "unprognostic (1.46e-1)" "unprognostic (2.12e-1)" "unprognostic (3.24e-2)" "unprognostic (3.99e-3)" "prognostic favorable (1.70e-4)" "unprognostic (4.34e-2)" "unprognostic (1.48e-1)" "unprognostic (2.19e-2)" "unprognostic (1.62e-1)" 27.1 25.4 21.4 17.1 23.7 17.2 30.6 32.9 20.1 47.9 47.8 36.7 33.3 46.8 21.0 30.4 37.3 22.1 19.9 22.8 25.5 31.7 5.7 33.1 9.4 24.3 24.1 41.8 40.7 21.9 23.6 24.7 22.0 38.6 29.2 55.4 36.7 24.0 22.8 16.7 33.4 30.0 22.1 21.6 36.9 19.7 28.8 9.0 53.9 19.8 9.1 29.9 30.9 23.7 87.3 96.5 83.6 70.2 43.9 43.0 46.1 66.4 77.0 61.2 69.3 60.4 99.7 0.1 33.6 66.9 38.6 67.2 83.8 106.5 45.8 0.3 63.8 63.8 61.6 1.3 91.7 27.2 48.9 37.1 82.7 63.5 125.5 80.9 79.1 4.9 2.6 0.5 38.7 96.5 3.0 27.8 63.0 90.3 61.3 77.4 35.0 0.8 72.5 38.8 25.5 73.1 64.7 56.0 86.5 64.7 39.7 43.9 64.4 36.8 46.2 53.0 57.9 1.4 5.3 0.3 46.1 0.3 37.1 30.8 8.5 16.4 8.5 9.0 1.1 0.5 0.4 2.3 11.2 0.3 0.5 3.6 14.3 34.6 22.4 9.4 0.3 4.7 21.4 23.7 32.9 20.1 22.8 25.5 24.3 24.1 22.0 22.1 28.8 23.7 64.7 32.1 27.2 72.1 4.0 47.2 83.4 41.5 33.6 182.5 75.8 59.8 32.7 55.8 53.2 38.6 158.4 22.3 50.7 81.7 68.4 69.3 29.9 125.0 65.1 63.0 55.0 42.3 41.8 60.8 70.5 42.3 40.2 163.0 17.7 43.1 61.4 1.2 29.6 107.7 35.0 93.9 50.8 49.3 46.9 38.1 60.3 47.0 58.7 127.4 60.6 63.2 124.6 44.2 87.1 83.8 61.6 77.8 6.9 89.3 45.1 31.6 94.1 107.5 59.2 59.6 67.0 12.7 45.5 42.1 39.8 19.3 15.3 81.3 106.1 102.7 CTNND1 "CTNND, KIAA0384, p120, p120cas, p120ctn" ENSG00000198561 "Catenin delta 1" O60716 11 57753243-57819546 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Cell adhesion, Transcription, Transcription regulation, Wnt signaling pathway" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 305.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 4.9;intermediate monocyte: 9.5;myeloid DC: 6.3;non-classical monocyte: 5.6" "Group enriched" "Detected in many" 19 "dendritic cells: 6.3;monocytes: 9.5" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB003837, HPA015954, HPA015955" Enhanced Enhanced "Plasma membrane" NA NA 200000 "Cluster 7: Monocytes - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane" "CAB003837: AB_562066, HPA015954: AB_2669326, HPA015955: AB_1846068" "unprognostic (1.06e-2)" "unprognostic (1.60e-2)" "unprognostic (5.17e-3)" "unprognostic (4.87e-2)" "unprognostic (7.81e-2)" "unprognostic (2.30e-1)" "unprognostic (2.98e-2)" "unprognostic (3.52e-3)" "unprognostic (4.17e-1)" "unprognostic (2.89e-2)" "prognostic unfavorable (3.02e-4)" "unprognostic (2.75e-1)" "prognostic favorable (3.54e-4)" "unprognostic (7.17e-2)" "unprognostic (4.09e-2)" "unprognostic (3.34e-1)" "unprognostic (7.33e-2)" 72.6 48.8 29.6 34.8 28.1 5.9 83.3 28.2 33.0 86.0 50.0 107.9 97.8 70.8 49.3 209.7 58.4 56.3 49.0 26.6 26.8 77.9 82.6 83.9 19.0 34.8 30.6 49.3 120.0 76.1 57.7 106.0 32.5 78.9 102.0 23.5 121.8 57.1 26.8 129.4 104.9 54.8 32.3 51.5 105.4 44.3 38.0 24.4 98.6 19.9 48.4 83.5 111.9 33.5 156.6 106.4 70.2 63.3 46.1 71.6 141.7 65.1 78.8 58.5 55.6 88.5 163.9 1.0 113.2 72.5 50.9 201.7 58.8 97.4 71.1 1.0 21.9 32.0 35.8 109.9 52.6 5.0 52.7 70.0 133.5 67.1 73.5 103.8 197.2 1.7 55.1 0.4 55.1 48.0 1.7 13.9 54.7 101.2 56.5 0.7 67.4 1.3 90.2 171.0 4.9 40.1 91.5 133.6 113.1 176.3 138.9 6.1 166.0 59.6 50.3 53.2 34.6 1.2 0.9 2.3 53.2 3.4 111.5 0.0 4.9 0.1 0.0 9.5 0.2 0.2 0.0 0.1 6.3 0.3 0.0 0.0 0.2 0.4 5.6 1.4 0.1 1.1 29.6 28.1 28.2 33.0 26.6 26.8 34.8 30.6 32.5 32.3 38.0 33.5 116.2 147.4 84.0 0.0 8.8 117.1 96.9 82.9 126.9 21.0 101.5 70.5 17.5 125.8 96.6 141.6 39.6 94.0 2.3 305.5 13.7 106.7 14.1 91.1 58.5 98.6 86.2 21.3 0.0 97.2 85.6 34.5 165.1 139.4 32.4 61.1 91.8 127.6 44.4 15.2 0.0 160.7 52.9 64.3 55.5 10.5 28.3 46.4 48.0 0.0 28.5 30.2 2.1 0.0 0.0 141.8 169.3 38.4 5.0 116.9 179.6 57.6 88.2 26.4 26.3 32.3 38.1 37.0 21.1 285.1 200.5 90.8 6.2 39.9 127.0 194.6 CTSH "ACC-4, ACC-5, ACC4, ACC5, CPSB" ENSG00000103811 "Cathepsin H" P09668 15 78921058-78949574 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 349.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 1569.9;Proximal tubular cells: 523.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 208.5;intermediate monocyte: 137.7;memory B-cell: 83.3;myeloid DC: 183.6;naive B-cell: 56.0;non-classical monocyte: 94.8" "Group enriched" "Detected in all" 5 "B-cells: 83.3;dendritic cells: 183.6;monocytes: 208.5" "Cell line enhanced" "Detected in many" "CAPAN-2: 306.4;HaCaT: 228.2;HDLM-2: 183.0;OE19: 197.4;RT4: 362.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000458, HPA003524" Enhanced Supported "Vesicles,Cytosol,Cytoplasmic bodies" "Intracellular and membrane" NA NA 8700000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 11: Alveolar cells - Smell perception" "Vesicles, Cytosol, Cytoplasmic bodies" "CAB000458: , HPA003524: AB_1846075" "unprognostic (6.47e-2)" "unprognostic (4.65e-3)" "unprognostic (1.05e-1)" "prognostic favorable (6.90e-4)" "unprognostic (4.37e-2)" "unprognostic (1.93e-1)" "unprognostic (7.18e-2)" "unprognostic (3.30e-3)" "unprognostic (2.22e-1)" "unprognostic (5.96e-2)" "unprognostic (4.10e-2)" "unprognostic (3.89e-2)" "unprognostic (6.63e-3)" "unprognostic (3.83e-1)" "unprognostic (4.42e-2)" "unprognostic (2.70e-3)" "unprognostic (1.79e-3)" 34.3 36.4 29.4 100.6 30.2 36.9 48.8 29.9 47.1 112.8 31.4 32.5 77.8 46.7 26.8 37.9 57.6 104.6 51.3 29.6 32.9 238.2 89.5 349.6 191.8 30.8 31.4 30.0 75.5 77.6 10.1 25.7 31.5 59.7 27.3 4.7 63.0 70.7 16.3 48.4 56.7 43.1 30.7 51.8 93.9 10.1 32.7 51.8 27.7 37.7 131.3 202.2 30.6 32.4 122.0 10.0 1.2 30.5 5.4 0.5 20.3 8.6 3.0 13.9 7.0 17.6 306.4 34.6 12.6 0.0 13.5 228.2 5.2 52.6 10.1 183.0 0.4 3.0 1.3 38.4 12.1 0.4 7.1 5.6 10.7 0.2 0.0 59.4 1.0 5.9 76.0 0.0 17.9 2.8 32.6 87.8 8.9 197.4 4.9 0.3 0.4 5.9 49.9 362.1 2.6 5.2 41.5 27.8 75.4 10.1 12.5 48.0 16.4 0.2 6.2 0.0 5.3 0.8 92.4 19.5 0.1 89.2 12.3 0.0 208.5 2.0 7.6 137.7 29.7 83.3 20.5 7.4 183.6 56.0 1.8 3.8 8.7 3.2 94.8 22.9 18.3 147.5 29.4 30.2 29.9 47.1 29.6 32.9 30.8 31.4 31.5 30.7 32.7 32.4 169.8 237.2 1569.9 59.1 127.4 24.2 280.7 363.9 30.1 1.3 45.5 41.7 26.2 358.9 258.7 367.8 4.2 19.8 8.1 9.1 84.1 225.0 25.3 67.0 86.0 124.5 9.1 3.0 2.2 142.0 39.6 53.8 106.0 42.8 32.8 2.7 14.3 115.5 256.7 0.0 2.9 18.6 101.7 177.8 259.6 22.6 73.0 350.4 80.0 15.9 360.9 22.6 5.2 1.5 1.1 84.6 16.0 6.0 155.8 112.0 153.0 523.2 261.6 6.6 19.7 4.5 22.3 12.3 56.4 41.6 18.6 23.4 29.4 17.8 40.1 340.4 CTTNBP2NL DKFZp547A023 ENSG00000143079 "CTTNBP2 N-terminal like" Q9P2B4 1 112396214-112463456 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Langerhans cells: 131.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 8.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "TIME: 68.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007301 Approved Approved "Nucleoli fibrillar center,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 41: Macrophages - Immune response" "Nucleoli fibrillar center, Cytosol" "HPA007301: AB_1847693" "unprognostic (1.81e-1)" "unprognostic (1.52e-1)" "prognostic favorable (1.14e-4)" "unprognostic (4.21e-3)" "unprognostic (4.54e-2)" "unprognostic (1.03e-1)" "unprognostic (2.48e-2)" "unprognostic (1.22e-1)" "unprognostic (2.61e-2)" "unprognostic (1.30e-1)" "unprognostic (1.29e-3)" "unprognostic (1.05e-1)" "prognostic favorable (8.08e-4)" "unprognostic (1.38e-1)" "unprognostic (1.63e-1)" "unprognostic (9.99e-2)" "unprognostic (5.12e-2)" 14.5 4.8 5.6 10.3 4.6 0.5 11.3 4.4 6.1 11.8 3.1 15.5 7.5 15.2 4.7 19.5 8.4 16.5 6.3 4.4 7.6 9.1 5.6 13.0 6.2 7.3 6.6 9.4 4.6 7.4 3.5 20.2 7.1 8.9 14.8 8.2 7.0 9.2 3.0 15.4 10.5 13.5 5.7 10.6 8.6 5.8 5.9 4.3 8.3 6.9 8.2 15.6 11.8 7.6 21.8 7.9 25.7 12.2 17.0 22.3 8.6 33.6 31.4 21.4 21.1 6.1 10.7 3.4 13.2 25.4 10.5 17.4 16.9 23.2 24.9 7.1 8.1 4.6 13.1 4.9 19.7 1.6 7.8 26.4 14.0 26.5 23.0 24.5 52.7 5.7 4.2 3.0 29.9 6.4 3.0 0.6 16.6 6.1 12.3 5.3 24.0 0.0 32.6 15.9 12.6 13.2 26.0 5.3 13.3 24.5 4.3 1.8 68.5 21.3 24.9 22.0 15.8 0.4 3.1 0.1 22.1 2.0 57.0 0.0 2.6 0.0 0.0 2.1 0.0 0.1 0.0 0.0 8.6 0.3 0.0 0.0 0.1 0.0 0.4 3.7 2.0 0.4 5.6 4.6 4.4 6.1 4.4 7.6 7.3 6.6 7.1 5.7 5.9 7.6 100.4 57.7 22.4 17.6 4.4 38.7 30.2 32.0 24.5 10.2 12.3 9.5 9.7 7.2 41.4 22.0 6.2 17.6 4.6 64.0 3.9 39.1 3.3 29.1 30.7 71.6 8.3 3.6 44.1 21.6 12.8 24.2 14.8 58.5 19.0 17.8 41.7 1.6 13.5 5.0 31.2 27.4 30.5 29.7 131.7 4.0 10.5 40.8 16.0 81.5 30.5 11.0 0.0 30.2 25.1 47.7 52.7 11.3 0.7 25.4 21.7 22.6 17.5 7.9 19.7 20.1 29.2 16.8 16.7 25.0 60.7 25.4 2.7 9.1 24.4 69.3 CUX2 "CDP2, CUTL2, KIAA0293" ENSG00000111249 "Cut like homeobox 2" O14529 12 111034165-111350554 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 20.6;choroid plexus: 25.7;liver: 20.4;prostate: 11.4" "Cell type enhanced" "Detected in some" "dendritic cells: 28.1;Excitatory neurons: 175.4;Hepatocytes: 50.9;Horizontal cells: 26.9;Inhibitory neurons: 72.5" "Group enriched" "Detected in some" 4 "liver cancer: 5.2;prostate cancer: 11.2" "Region enhanced" "Detected in many" "cerebral cortex: 20.6" "Immune cell enriched" "Detected in single" 70 "plasmacytoid DC: 6.9" "Lineage enriched" "Detected in single" 70 "dendritic cells: 6.9" "Cell line enhanced" "Detected in some" "HBEC3-KT: 6.6;HDLM-2: 2.9;hTERT-HME1: 3.5;SCLC-21H: 6.5;SH-SY5Y: 14.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (3.87e-2)" "unprognostic (6.98e-3)" "unprognostic (1.17e-1)" "unprognostic (1.17e-1)" "unprognostic (1.30e-1)" "unprognostic (2.78e-2)" "unprognostic (1.22e-2)" "unprognostic (9.44e-2)" "unprognostic (2.33e-1)" "unprognostic (3.30e-2)" "unprognostic (7.83e-5)" "unprognostic (2.67e-1)" "unprognostic (3.54e-3)" "unprognostic (4.31e-2)" "unprognostic (9.03e-2)" "unprognostic (4.64e-2)" "unprognostic (1.90e-2)" 0.0 0.0 2.3 0.2 1.4 0.2 1.8 0.0 20.6 0.8 25.7 0.3 0.1 0.1 0.3 0.1 0.0 0.0 0.0 3.5 0.0 0.2 20.4 0.0 0.5 0.0 1.5 0.0 0.1 0.0 2.1 0.0 0.0 11.4 0.0 2.3 0.0 2.9 0.1 0.2 0.2 0.0 0.0 0.2 1.5 0.5 5.2 0.2 4.2 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 6.6 0.0 2.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 2.1 0.0 0.0 0.2 0.0 0.1 0.0 0.0 6.5 14.0 0.0 0.0 0.0 0.4 0.3 0.2 0.0 0.0 0.8 0.0 0.0 0.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 2.3 1.4 0.0 20.6 3.5 0.0 0.0 1.5 0.0 0.0 5.2 0.0 0.0 0.0 0.0 7.2 0.5 0.0 3.5 0.7 0.0 6.4 2.6 3.0 1.0 2.8 0.1 0.0 0.0 0.0 28.1 0.1 0.0 0.0 1.2 3.7 0.1 0.1 0.0 2.7 175.4 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.4 50.9 0.7 26.9 72.5 0.0 0.0 0.6 0.0 0.6 0.0 0.5 0.0 1.9 0.0 0.1 0.0 20.1 1.8 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.1 0.9 0.0 0.3 0.1 0.8 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.6 CXXC4 IDAX ENSG00000168772 "CXXC finger protein 4" 4 104468308-104494901 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 16.1;retina: 7.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 48.0;Cone photoreceptor cells: 31.3;Enteroendocrine cells: 102.1;Horizontal cells: 45.4;Oligodendrocyte precursor cells: 64.3;Oligodendrocytes: 30.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 7.0;AN3-CA: 9.7;Karpas-707: 9.0;RPMI-8226: 5.5;SCLC-21H: 12.0;U-266/70: 9.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036600, HPA036925" Uncertain Uncertain "Nucleoplasm,Golgi apparatus" NA NA "Cluster 58: Brain - Synaptic function" "Cluster 12: NES - Nervous system development" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Golgi apparatus" Nucleoplasm "HPA036600: AB_10673659, HPA036925: " "unprognostic (1.37e-2)" "unprognostic (1.12e-1)" "unprognostic (5.75e-2)" "unprognostic (5.86e-2)" "unprognostic (9.07e-3)" "unprognostic (1.14e-1)" "unprognostic (1.75e-2)" "unprognostic (9.69e-3)" "unprognostic (2.75e-1)" "unprognostic (2.45e-1)" "prognostic favorable (2.19e-4)" "unprognostic (1.82e-1)" "unprognostic (4.52e-3)" "unprognostic (5.69e-2)" "unprognostic (1.37e-1)" "unprognostic (2.38e-1)" "unprognostic (4.42e-3)" 0.6 1.3 4.9 0.1 3.9 0.0 1.4 3.0 16.1 0.7 0.2 1.3 1.8 0.4 1.7 0.1 2.3 0.3 1.9 4.3 10.1 0.4 0.8 0.6 0.0 5.0 6.1 1.8 3.0 0.7 4.4 0.3 4.5 0.5 0.8 7.3 2.9 0.4 0.3 0.2 1.9 0.4 4.4 0.4 1.3 1.6 11.9 0.5 2.4 0.1 0.0 0.2 0.3 4.8 0.0 0.2 7.0 9.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 2.8 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.4 0.0 0.9 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.1 0.0 9.0 0.0 0.0 2.7 0.0 2.5 0.1 0.1 0.0 0.0 5.5 0.0 0.1 12.0 2.2 0.0 0.6 0.0 2.8 0.3 0.0 0.0 0.0 1.5 0.0 0.1 9.7 2.6 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.9 3.9 3.0 16.1 4.3 10.1 5.0 6.1 4.5 4.4 11.9 4.8 12.4 0.0 6.4 10.4 0.1 0.3 1.0 0.8 1.2 48.0 8.4 5.6 15.9 2.8 2.2 0.0 31.3 0.2 0.8 0.4 0.0 0.1 0.3 13.0 0.9 2.9 102.1 0.0 23.8 3.3 0.0 1.0 0.0 0.6 0.0 1.2 1.1 2.7 0.1 45.4 27.5 6.2 0.0 0.3 0.3 0.9 0.3 0.1 1.8 0.0 0.0 13.8 1.0 64.3 30.8 1.5 1.2 10.9 0.3 0.6 10.2 1.1 12.6 26.7 0.0 15.6 0.9 0.0 4.8 0.1 0.0 0.3 0.5 0.1 2.6 0.5 CYP2J2 ENSG00000134716 "Cytochrome P450 family 2 subfamily J member 2" P51589 1 59893308-59926773 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 89.7;intestine: 83.4;liver: 146.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 91.4;Cytotrophoblasts: 116.2;Hepatocytes: 58.3;Oligodendrocytes: 68.5;Proximal enterocytes: 134.6;Syncytiotrophoblasts: 240.9" "Cancer enhanced" "Detected in many" "renal cancer: 32.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 2.9;naive CD8 T-cell: 2.6" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 5 "OE19: 16.9;RT4: 62.3;SK-BR-3: 16.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "unprognostic (3.53e-2)" "unprognostic (1.22e-2)" "unprognostic (1.35e-2)" "unprognostic (1.99e-2)" "unprognostic (2.51e-2)" "unprognostic (2.28e-1)" "unprognostic (1.61e-1)" "unprognostic (3.16e-1)" "unprognostic (1.15e-1)" "unprognostic (2.84e-2)" "unprognostic (7.29e-2)" "unprognostic (2.66e-1)" "prognostic unfavorable (5.54e-7)" "unprognostic (4.96e-1)" "unprognostic (8.45e-2)" "unprognostic (4.25e-1)" "unprognostic (9.70e-2)" 1.2 0.4 18.3 1.2 22.1 0.1 9.3 23.6 19.1 2.3 8.4 19.0 34.1 1.0 0.8 13.1 0.9 2.0 89.7 14.7 19.4 3.0 146.2 1.4 0.2 20.7 20.7 0.0 2.2 0.0 0.9 22.3 18.9 3.3 21.3 3.5 14.5 0.7 25.3 8.9 83.4 1.8 20.2 0.1 4.7 0.6 28.0 0.5 0.1 6.4 0.7 5.8 3.6 21.8 0.2 0.0 0.1 0.0 0.0 0.3 0.0 0.0 2.7 0.1 1.2 0.3 2.8 0.0 0.8 0.0 3.5 0.9 0.0 0.9 0.0 0.0 1.7 0.0 0.0 0.5 0.0 0.0 0.1 0.5 0.9 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.6 3.2 0.0 0.0 1.5 16.9 2.6 0.0 6.3 0.0 3.4 62.3 0.9 3.8 0.1 16.4 0.6 0.1 4.1 0.0 0.0 2.2 2.5 0.0 0.9 1.9 0.1 0.0 0.5 0.0 6.9 0.0 0.0 0.0 0.1 0.0 0.6 0.8 0.3 0.2 0.0 0.4 2.9 2.6 0.0 0.4 0.0 0.6 0.0 0.4 18.3 22.1 23.6 19.1 14.7 19.4 20.7 20.7 18.9 20.2 28.0 21.8 0.0 3.2 4.1 35.6 0.7 0.4 1.7 5.5 7.4 0.0 5.1 3.0 91.4 11.5 28.9 0.0 0.0 116.2 0.1 26.4 0.0 9.5 22.7 3.1 1.7 1.3 9.0 0.0 0.1 0.9 9.3 2.3 4.1 7.7 0.0 1.5 0.0 58.3 7.0 0.0 0.4 18.7 6.1 0.8 0.3 23.3 0.0 0.2 0.0 1.9 0.6 12.5 0.0 29.7 68.5 2.0 18.1 0.0 0.3 1.5 134.6 2.5 20.1 0.9 0.0 0.7 1.0 0.3 0.2 7.3 2.3 240.9 0.2 0.4 24.1 2.1 CYP2W1 "FLJ20359, MGC34287" ENSG00000073067 "Cytochrome P450 family 2 subfamily W member 1" Q8TAV3 7 983181-989640 "Predicted intracellular proteins" "Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "adrenal gland: 19.1;intestine: 6.1;skin 1: 10.5" "Cell type enriched" "Detected in some" 7 "Enteroendocrine cells: 98.5" "Group enriched" "Detected in many" 5 "colorectal cancer: 25.3;stomach cancer: 15.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "CACO-2: 13.5;Hep G2: 49.8" "Not detected" "Not detected" "Not detected" "Not detected" "Intracellular and membrane" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (7.09e-3)" "unprognostic (1.94e-2)" "unprognostic (2.75e-2)" "unprognostic (1.51e-3)" "unprognostic (1.57e-1)" "unprognostic (1.22e-1)" "unprognostic (1.97e-1)" "unprognostic (2.50e-2)" "unprognostic (1.41e-1)" "unprognostic (1.52e-1)" "unprognostic (2.28e-1)" "unprognostic (6.26e-2)" "unprognostic (2.72e-5)" "unprognostic (7.52e-2)" "unprognostic (1.34e-1)" "unprognostic (1.60e-1)" "prognostic unfavorable (5.85e-4)" 0.1 19.1 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.4 0.0 0.9 6.1 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 1.4 0.3 0.0 0.3 1.0 0.1 2.1 0.5 0.2 0.3 0.2 0.0 10.5 1.0 0.0 0.0 0.4 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.7 1.0 0.1 0.1 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.5 0.3 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.2 0.0 0.2 49.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.3 0.0 2.2 0.0 0.5 0.1 0.1 0.0 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.6 4.3 0.0 0.0 0.1 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 3.2 0.0 0.0 0.0 4.0 2.3 1.5 0.0 0.6 0.0 0.0 0.5 0.0 2.6 0.0 0.0 1.1 0.0 3.7 0.0 0.1 0.1 0.1 0.0 0.3 98.5 0.0 0.0 0.9 0.6 10.2 0.0 0.1 0.0 0.3 0.0 0.0 1.1 0.0 0.0 13.6 0.0 0.0 0.9 0.0 1.8 0.3 0.0 0.0 0.1 10.5 0.0 0.0 0.0 0.1 3.3 0.0 0.1 1.2 1.1 0.0 3.3 0.6 0.0 0.8 0.3 0.2 0.1 0.0 4.4 1.9 0.2 4.4 11.4 3.7 CYSRT1 "C9orf169, MGC59937" ENSG00000197191 "Cysteine rich tail 1" A8MQ03 9 137224635-137226315 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "esophagus: 239.5" "Group enriched" "Detected in some" 10 "Pancreatic endocrine cells: 58.0;Squamous epithelial cells: 66.0" "Cancer enhanced" "Detected in all" "head and neck cancer: 23.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 25.1;CAPAN-2: 28.9;HaCaT: 33.3;HeLa: 30.6;MCF7: 49.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA021883, HPA021886" Approved Approved "Nuclear speckles,Vesicles,Midbody" Yes No "Cluster 7: Monocytes - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 61: Squamous epithelial cells - Keratinization" "Nuclear speckles" "Vesicles, Midbody" "HPA021883: AB_1853190, HPA021886: AB_1853192" "unprognostic (1.35e-1)" "unprognostic (2.53e-2)" "unprognostic (8.31e-3)" "unprognostic (6.87e-3)" "unprognostic (2.14e-1)" "unprognostic (2.66e-2)" "unprognostic (8.11e-2)" "unprognostic (5.86e-2)" "unprognostic (3.45e-1)" "unprognostic (2.73e-1)" "unprognostic (1.24e-2)" "unprognostic (1.05e-1)" "unprognostic (6.24e-3)" "unprognostic (7.92e-3)" "unprognostic (1.99e-1)" "unprognostic (1.03e-1)" "unprognostic (2.29e-1)" 0.6 1.1 0.6 0.2 0.4 0.4 1.5 0.3 1.6 43.1 0.0 0.6 0.4 0.5 0.4 239.5 1.8 0.7 0.9 0.8 0.8 3.7 1.7 1.1 0.7 1.4 1.3 0.3 1.5 0.6 7.3 0.3 0.6 2.6 0.1 0.6 29.9 0.5 0.4 34.4 0.8 0.0 1.0 0.7 2.0 4.1 0.9 0.3 2.4 0.0 14.3 1.2 57.7 0.5 25.1 2.4 1.8 3.9 0.0 0.1 5.3 0.4 0.4 0.5 0.2 1.3 28.9 1.3 1.2 0.3 0.7 33.3 0.5 7.0 0.0 2.7 1.8 0.3 30.6 16.8 0.9 0.2 1.4 0.4 3.5 0.9 0.2 1.3 0.3 1.4 0.6 3.1 1.6 49.5 0.7 1.0 0.7 4.8 3.0 2.4 2.8 3.5 0.6 1.6 0.4 1.8 4.5 3.5 0.9 1.5 7.7 0.4 1.0 1.1 0.9 3.2 0.6 1.9 1.7 1.2 1.4 1.3 1.4 0.2 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.9 0.0 0.0 0.0 0.6 0.4 0.3 1.6 0.8 0.8 1.4 1.3 0.6 1.0 0.9 0.5 0.0 0.0 1.1 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.7 0.5 0.4 1.5 2.5 5.5 0.0 0.6 0.1 0.4 0.0 4.6 0.5 2.1 0.2 0.3 0.0 0.0 0.3 5.8 0.2 0.1 3.1 1.7 0.0 0.6 0.7 0.8 0.2 0.0 0.3 0.6 0.0 0.3 0.0 0.3 0.0 0.2 0.0 0.0 0.1 0.5 0.0 0.0 0.0 58.0 1.1 0.4 0.1 0.2 1.6 0.9 0.0 0.6 0.0 0.3 0.3 3.0 1.1 66.0 0.0 0.0 0.1 0.9 0.5 1.7 CYYR1 C21orf95 ENSG00000166265 "Cysteine and tyrosine rich 1" Q96J86 21 26466209-26573286 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Adipocytes: 200.0;Endothelial cells: 150.0;Hepatic stellate cells: 79.9;Microglial cells: 58.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 38 "plasmacytoid DC: 31.4" "Lineage enriched" "Detected in single" 82 "dendritic cells: 31.4" "Cell line enhanced" "Detected in some" "AF22: 14.1;NTERA-2: 39.2;PC-3: 11.0;RH-30: 16.6;SCLC-21H: 33.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034921, HPA067685" Uncertain Approved Nucleoplasm NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "CAB034921: AB_2089315, HPA067685: AB_2685887" "unprognostic (5.64e-2)" "unprognostic (2.59e-2)" "unprognostic (1.37e-1)" "unprognostic (1.88e-1)" "unprognostic (7.00e-2)" "unprognostic (2.63e-2)" "unprognostic (2.88e-3)" "unprognostic (4.04e-1)" "unprognostic (1.11e-2)" "unprognostic (1.12e-1)" "unprognostic (3.77e-2)" "unprognostic (1.46e-1)" "unprognostic (2.44e-3)" "unprognostic (9.29e-3)" "unprognostic (2.26e-1)" "unprognostic (1.88e-1)" "unprognostic (1.49e-2)" 36.4 46.4 9.7 8.1 9.0 7.8 30.2 8.7 11.4 16.4 8.4 8.4 6.1 19.2 8.1 9.0 12.9 16.1 22.3 8.1 9.4 12.7 4.8 23.7 6.0 9.9 10.5 4.5 5.5 15.5 3.8 36.3 10.6 9.5 6.6 0.9 6.8 11.4 15.1 8.2 9.6 23.6 9.6 32.5 7.7 1.9 10.8 6.0 14.1 31.8 4.6 12.6 9.5 9.4 0.0 0.0 14.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 7.1 1.6 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 6.5 0.0 0.4 0.0 5.6 0.0 0.0 0.0 2.6 0.0 0.0 0.1 39.2 0.0 11.0 0.0 16.6 0.0 1.7 0.0 33.7 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 3.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.3 0.0 0.0 31.4 0.0 0.1 9.7 9.0 8.7 11.4 8.1 9.4 9.9 10.5 10.6 9.6 10.8 9.4 200.0 0.0 0.6 1.6 1.5 11.7 2.0 10.2 27.3 0.1 14.9 15.0 6.7 0.0 1.7 14.7 0.0 0.1 14.9 0.0 3.9 0.0 0.7 0.4 6.9 150.0 0.0 11.1 1.6 0.0 0.2 8.3 0.0 0.4 0.0 3.7 79.9 0.4 0.3 0.0 4.6 0.0 2.0 3.2 8.0 1.5 2.1 1.4 7.2 58.1 0.7 0.5 0.0 0.0 0.7 0.1 0.0 0.0 2.5 1.1 0.0 6.8 1.1 0.3 0.0 13.3 4.4 0.2 1.3 4.9 5.4 0.3 1.5 0.4 0.0 0.7 DAAM1 KIAA0666 ENSG00000100592 "Dishevelled associated activator of morphogenesis 1" Q9Y4D1 14 59188646-59371405 "Plasma proteins, Predicted intracellular proteins" "Wnt signaling pathway" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 467.3;Suprabasal keratinocytes: 332.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HaCaT: 39.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026605, HPA064789" Uncertain Approved "Plasma membrane,Cytosol" NA NA 9700 "Cluster 6: Non-specific - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "Plasma membrane, Cytosol" "HPA026605: AB_1847464, HPA064789: AB_2685352" "unprognostic (2.81e-1)" "unprognostic (9.70e-2)" "unprognostic (3.85e-2)" "unprognostic (2.74e-1)" "unprognostic (2.32e-1)" "unprognostic (1.84e-1)" "unprognostic (1.76e-2)" "unprognostic (2.48e-1)" "unprognostic (2.02e-1)" "unprognostic (6.40e-2)" "unprognostic (1.98e-1)" "unprognostic (4.64e-2)" "prognostic favorable (3.77e-4)" "unprognostic (5.01e-2)" "unprognostic (3.29e-1)" "unprognostic (1.39e-1)" "unprognostic (3.15e-2)" 14.5 6.2 13.0 6.8 13.6 5.4 10.4 12.6 12.8 13.6 22.8 13.5 4.8 13.5 5.6 19.0 7.7 5.9 19.3 11.8 14.8 6.9 12.6 10.5 11.1 7.9 8.1 8.0 9.3 20.6 5.3 9.1 8.3 11.9 8.5 24.9 9.4 11.0 5.6 30.9 7.2 10.9 7.8 13.1 7.0 6.9 11.2 4.8 7.4 4.7 15.6 9.5 15.1 10.7 18.2 1.9 13.1 3.5 7.8 5.8 17.1 2.5 2.3 4.7 4.8 9.4 16.6 20.4 4.4 5.6 9.6 39.7 11.8 10.0 4.0 9.0 4.1 6.8 4.8 11.8 4.8 7.9 3.8 3.9 10.6 3.9 4.7 10.8 11.3 10.2 11.9 9.9 2.8 17.0 6.9 4.9 7.5 12.9 5.6 6.3 11.1 2.0 6.8 13.5 20.3 4.8 15.8 23.1 16.1 8.7 30.5 2.1 10.8 3.9 7.4 8.4 2.2 2.2 2.7 22.1 5.0 1.5 8.7 7.7 2.0 2.6 2.3 2.4 3.0 10.8 3.0 2.3 2.2 4.6 2.4 2.6 2.8 6.7 3.5 18.3 4.0 1.9 13.0 13.6 12.6 12.8 11.8 14.8 7.9 8.1 8.3 7.8 11.2 10.7 62.2 35.3 27.0 160.6 37.8 467.3 172.4 128.6 30.7 110.7 56.8 40.6 149.3 38.6 82.3 29.5 308.6 33.0 66.9 47.0 23.5 63.8 40.0 68.4 142.9 71.9 87.7 140.0 143.7 93.1 27.6 67.3 21.9 54.6 26.0 155.2 102.4 47.2 32.8 195.2 202.0 56.7 73.2 16.3 55.8 16.6 60.3 36.1 90.7 66.5 25.2 96.5 16.5 74.9 24.3 191.4 45.1 74.1 30.8 104.2 24.7 12.8 102.4 168.7 32.9 84.6 66.3 51.3 46.3 52.8 332.0 34.2 25.1 25.1 38.1 84.2 DACH1 DACH ENSG00000276644 "Dachshund family transcription factor 1" Q9UI36 13 71437966-71867204 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 88.5;Excitatory neurons: 77.0;Horizontal cells: 87.5;Late spermatids: 103.7;Microglial cells: 143.4;Muller glia cells: 143.8;Spermatocytes: 58.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 15 "basophil: 4.2;eosinophil: 8.4;NK-cell: 4.2;plasmacytoid DC: 6.4" "Group enriched" "Detected in many" 33 "dendritic cells: 6.4;granulocytes: 8.4;NK-cells: 4.2" "Cell line enhanced" "Detected in some" "AF22: 14.2;HAP1: 22.5;HEK 293: 16.8;HL-60: 37.9;NB-4: 16.7;SCLC-21H: 36.9;SH-SY5Y: 29.5;THP-1: 26.9" "Region enriched" "Detected in all" 5 "basal ganglia: 38.8" "Region enriched" "Detected in all" 5 "basal ganglia: 34.2" "HPA012672, HPA012938, HPA073222" Approved Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Nuclear speckles" "HPA012672: AB_1847466, HPA012938: , HPA073222: " "unprognostic (3.16e-1)" "unprognostic (5.26e-2)" "unprognostic (1.41e-2)" "unprognostic (2.36e-1)" "unprognostic (4.21e-2)" "unprognostic (5.63e-2)" "unprognostic (2.22e-2)" "unprognostic (8.08e-3)" "unprognostic (2.12e-2)" "unprognostic (2.50e-1)" "unprognostic (3.04e-3)" "unprognostic (4.37e-1)" "unprognostic (2.18e-2)" "unprognostic (1.06e-1)" "unprognostic (2.19e-1)" "unprognostic (1.24e-1)" "unprognostic (5.17e-2)" 4.4 11.1 2.3 1.2 14.0 6.0 4.0 1.6 2.9 9.7 0.3 3.1 5.2 3.8 1.3 0.9 2.8 7.2 2.2 1.0 4.6 8.9 2.0 5.9 0.5 7.0 9.3 0.5 1.9 6.6 3.5 6.9 5.9 7.0 3.3 16.7 2.0 2.3 1.9 1.8 6.7 2.0 2.6 5.4 1.9 6.3 4.3 3.5 0.2 1.2 0.4 2.0 2.7 2.4 0.0 0.0 14.2 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 22.5 0.0 0.0 0.0 16.8 0.2 0.0 0.0 0.4 37.9 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.9 16.7 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 36.9 29.5 0.0 0.0 0.0 0.1 0.9 26.9 0.0 0.4 0.3 0.0 0.8 0.0 0.0 0.0 1.0 0.0 0.2 4.2 0.1 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 4.2 0.0 6.4 0.0 0.1 2.3 14.0 1.6 2.9 1.0 4.6 7.0 9.3 5.9 2.6 4.3 2.4 36.4 0.0 0.6 15.7 0.5 1.7 3.6 0.0 0.0 15.4 19.4 9.3 2.1 1.5 0.0 7.3 4.2 0.0 12.5 0.9 5.9 1.0 88.5 5.0 4.7 34.2 34.1 2.5 77.0 0.0 0.0 4.6 1.1 3.2 5.1 0.3 2.9 0.0 0.2 87.5 28.2 21.4 0.0 1.2 1.2 103.7 3.4 2.5 0.0 143.4 1.1 143.8 0.0 6.6 3.9 0.6 0.3 1.9 0.0 5.8 3.5 6.9 0.7 6.9 13.1 1.5 4.3 58.8 10.2 0.2 1.3 0.0 1.0 1.3 12.6 2.7 DBP DABP ENSG00000105516 "D-box binding PAR bZIP transcription factor" Q10586 19 48630030-48637379 "Metabolic proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 318.3;Horizontal cells: 215.4;Muller glia cells: 194.2;Rod photoreceptor cells: 108.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Karpas-707: 61.7;NB-4: 235.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 56: Bipolar cells - Visual perception" "unprognostic (1.49e-1)" "unprognostic (3.68e-3)" "unprognostic (2.16e-3)" "unprognostic (1.40e-1)" "unprognostic (4.67e-2)" "prognostic favorable (5.49e-4)" "unprognostic (2.00e-1)" "prognostic favorable (1.16e-5)" "unprognostic (3.32e-2)" "unprognostic (2.39e-1)" "unprognostic (4.24e-3)" "unprognostic (4.75e-2)" "prognostic favorable (2.41e-5)" "unprognostic (2.23e-1)" "unprognostic (2.52e-1)" "unprognostic (1.46e-2)" "unprognostic (3.61e-2)" 12.4 53.0 22.5 6.6 34.6 7.5 12.6 35.7 32.9 12.9 9.7 18.7 19.2 13.2 7.2 21.1 11.6 6.0 18.3 21.9 23.4 17.9 24.7 9.8 14.6 21.3 24.5 33.5 14.0 15.6 34.9 2.8 18.6 16.8 3.8 32.6 42.2 13.8 57.1 58.1 15.5 4.5 23.5 19.1 16.4 16.4 29.0 13.6 34.4 7.7 8.4 8.8 16.3 20.5 4.3 7.3 3.6 17.6 2.6 3.4 3.8 1.0 9.8 3.0 7.4 4.6 39.7 8.5 4.8 4.8 3.6 9.8 12.6 2.5 2.5 8.9 6.0 17.2 6.1 2.4 12.9 10.6 12.5 12.1 2.3 0.5 2.0 21.1 0.6 17.9 1.3 61.7 2.7 5.9 32.8 235.3 2.5 11.3 4.9 15.8 2.9 22.2 1.5 1.3 11.7 14.7 5.5 26.5 15.6 1.6 4.8 10.5 1.1 6.5 17.8 3.4 1.9 28.4 50.7 15.6 3.1 15.0 3.9 3.3 3.0 4.9 1.9 3.5 3.9 2.7 3.2 1.6 4.1 1.7 2.5 3.1 0.1 0.7 1.9 3.5 3.7 1.1 22.5 34.6 35.7 32.9 21.9 23.4 21.3 24.5 18.6 23.5 29.0 20.5 14.1 12.8 6.2 9.4 21.7 21.9 15.3 3.1 52.3 318.3 17.2 23.5 4.7 12.8 3.2 7.3 87.6 5.2 15.9 8.0 45.0 5.8 1.4 9.0 25.4 10.8 1.8 6.9 4.2 5.6 1.9 25.5 7.1 13.1 0.0 17.6 10.4 10.0 10.9 215.4 5.7 8.1 6.1 15.1 9.6 3.3 16.8 19.4 17.8 1.9 12.9 194.2 32.0 1.5 4.8 3.0 11.3 25.6 6.8 7.8 63.7 26.6 1.3 108.4 0.0 22.8 13.6 1.3 8.4 32.2 22.6 1.6 20.8 85.8 7.5 18.3 DCAF15 "C19orf72, MGC99481" ENSG00000132017 "DDB1 and CUL4 associated factor 15" Q66K64 19 13952492-13961449 "Predicted intracellular proteins" "Immunity, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068351 Approved Vesicles,Mitochondria NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 12: NES - Nervous system development" "Cluster 7: Non-specific - Mitochondria" Mitochondria Vesicles "HPA068351: AB_2685977" "unprognostic (6.91e-2)" "unprognostic (6.55e-3)" "unprognostic (3.03e-2)" "unprognostic (5.18e-3)" "unprognostic (1.95e-1)" "unprognostic (1.89e-2)" "unprognostic (1.83e-3)" "unprognostic (9.72e-2)" "unprognostic (8.03e-2)" "unprognostic (1.21e-1)" "prognostic favorable (7.97e-4)" "unprognostic (1.98e-2)" "prognostic unfavorable (1.34e-5)" "unprognostic (7.97e-3)" "unprognostic (1.26e-1)" "unprognostic (1.07e-1)" "unprognostic (1.59e-1)" 17.6 10.7 5.9 10.3 6.0 20.5 18.1 7.1 7.9 18.7 4.7 18.1 6.9 17.0 4.3 24.0 16.7 4.5 18.6 6.0 5.6 16.2 13.9 18.6 13.5 5.6 5.2 15.5 13.7 7.1 16.5 7.3 5.2 17.0 5.2 3.6 16.1 5.3 22.9 30.2 23.4 5.1 4.9 33.4 14.0 44.7 5.6 14.6 17.0 8.6 10.8 15.6 21.6 5.4 18.9 11.5 29.5 16.2 3.1 4.5 13.5 12.7 8.8 26.1 25.9 20.4 7.9 17.3 14.4 12.3 15.4 16.7 18.9 12.0 9.2 21.0 33.8 21.3 21.0 21.4 6.5 17.8 30.2 5.9 10.9 19.3 8.6 9.4 13.1 27.4 22.9 24.8 11.6 28.7 32.0 33.0 35.2 12.7 17.8 29.2 10.4 11.8 14.1 14.3 18.8 19.3 11.4 8.1 10.7 12.1 10.5 22.7 9.2 17.8 13.1 28.3 24.1 17.4 20.7 18.3 11.4 25.8 15.6 0.2 0.3 0.9 0.3 0.3 0.2 0.3 0.2 0.3 0.2 0.4 0.1 0.3 0.6 0.1 0.2 0.4 0.6 0.2 5.9 6.0 7.1 7.9 6.0 5.6 5.6 5.2 5.2 4.9 5.6 5.4 19.5 0.0 0.0 6.8 19.7 4.8 10.5 6.9 8.6 17.3 8.9 10.7 2.9 10.0 3.8 9.2 8.4 13.7 24.4 9.6 1.9 11.0 5.0 7.0 7.8 10.9 7.7 9.4 5.2 10.3 15.1 7.5 13.7 7.0 1.3 15.0 7.1 3.4 15.7 15.2 3.4 5.7 4.1 8.1 7.0 9.5 18.3 14.3 1.8 8.4 13.8 9.2 16.5 7.1 5.5 9.9 9.6 12.0 18.3 6.4 4.5 4.7 3.9 13.9 6.6 6.0 7.9 35.6 19.9 10.0 9.8 13.8 21.2 10.4 7.9 8.9 DCN "DSPG2, SLRR1B" ENSG00000011465 Decorin P07585 12 91140484-91183217 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Corneal dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 1218.7;Fibroblasts: 7960.2;Leydig cells: 6281.9;Peritubular cells: 1856.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "basophil: 24.5" "Lineage enriched" "Detected in single" 35 "granulocytes: 24.5" "Cell line enhanced" "Detected in many" "ASC diff: 3291.1;ASC TERT1: 2371.6;BJ hTERT+: 2546.6;HSkMC: 2289.4" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 8 "spinal cord: 544.7" "HPA003315, CAB017118, HPA064736, CAB068930" Enhanced "Secreted to extracellular matrix" NA NA 1900000 "Cluster 46: Basophils - DNA binding" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB017118: , CAB068930: AB_425394, HPA003315: AB_1078639, HPA064736: AB_2685340" "unprognostic (1.73e-1)" "unprognostic (1.90e-1)" "unprognostic (1.43e-1)" "unprognostic (3.22e-2)" "unprognostic (8.63e-2)" "unprognostic (1.34e-1)" "unprognostic (1.01e-2)" "unprognostic (2.68e-1)" "unprognostic (1.98e-1)" "unprognostic (6.12e-2)" "unprognostic (1.65e-1)" "unprognostic (5.15e-2)" "prognostic unfavorable (1.46e-5)" "unprognostic (3.06e-3)" "unprognostic (5.37e-2)" "unprognostic (1.59e-3)" "unprognostic (7.56e-3)" 1522.3 1171.7 60.6 272.0 80.0 4.4 2342.2 63.5 119.2 1493.0 111.6 549.9 163.5 1308.5 1302.0 932.8 1213.4 1802.7 2108.9 66.8 60.3 394.8 459.6 955.8 130.4 68.9 60.9 2681.4 257.9 80.2 112.0 1534.8 75.7 451.6 493.0 3.1 362.5 462.3 469.0 713.4 336.6 1027.8 70.2 20.0 434.5 279.6 72.8 183.0 479.3 1328.3 293.6 1895.5 783.7 57.9 0.2 0.4 4.4 0.6 3291.1 2371.6 6.2 608.7 2546.6 28.8 28.5 0.3 0.9 1.1 0.5 523.5 0.6 2.1 0.8 1.9 4.9 0.7 0.5 0.6 20.4 0.1 717.4 1.3 1.4 2289.4 8.9 78.3 38.5 12.1 1.0 0.2 0.8 0.7 63.0 0.6 1.5 10.8 1.2 0.4 1.6 0.7 2.3 2.8 3.4 0.5 2.7 11.9 10.3 1.1 0.9 1.8 0.6 0.4 0.9 132.3 1.2 497.5 0.6 3.3 3.1 2.0 8.0 2.0 0.8 24.5 0.3 0.6 0.3 0.1 0.3 0.3 0.3 0.2 0.1 0.6 0.4 0.4 2.7 0.4 0.2 0.7 0.2 0.0 60.6 80.0 63.5 119.2 66.8 60.3 68.9 60.9 75.7 70.2 72.8 57.9 351.1 41.7 44.1 2.3 4.1 609.1 5.4 0.0 264.6 1.9 25.5 31.5 154.7 10.0 11.8 20.2 0.0 31.2 12.8 0.0 1.9 1.0 25.0 39.4 1218.7 158.7 0.0 2.7 0.8 0.0 30.0 7960.2 54.0 22.0 21.5 0.2 214.9 1.4 58.8 0.0 17.1 0.1 0.0 2.8 962.7 103.0 6281.9 52.5 606.5 122.7 0.0 3.3 0.0 0.0 1.4 2.7 0.5 1856.9 23.2 5.8 0.0 0.4 5.8 0.7 210.4 236.8 408.2 13.4 9.2 36.8 482.5 63.9 72.3 70.2 0.0 10.7 DDO ENSG00000203797 "D-aspartate oxidase" Q99489 6 110391771-110415575 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 18.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 17.4;Muller glia cells: 8.2;Oligodendrocytes: 13.3;Paneth cells: 8.5;Proximal enterocytes: 8.5;Proximal tubular cells: 12.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 3.3;myeloid DC: 4.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "GAMG: 11.5;RPMI-8226: 15.9;U-937: 17.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037525, HPA037526" Enhanced Enhanced Cytosol NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" Cytosol "HPA037525: AB_2675523, HPA037526: AB_10672352" "unprognostic (1.37e-1)" "unprognostic (1.54e-1)" "unprognostic (6.51e-2)" "unprognostic (1.30e-2)" "unprognostic (2.00e-1)" "unprognostic (3.28e-2)" "unprognostic (3.71e-2)" "unprognostic (1.01e-2)" "unprognostic (2.05e-1)" "unprognostic (2.91e-1)" "unprognostic (6.97e-2)" "unprognostic (1.43e-1)" "prognostic favorable (8.69e-5)" "unprognostic (3.51e-4)" "unprognostic (3.36e-3)" "unprognostic (1.27e-3)" "unprognostic (9.06e-2)" 1.9 8.2 4.5 0.8 7.0 1.4 2.5 5.0 4.8 1.9 4.3 2.3 7.4 2.1 2.7 0.8 4.9 2.9 18.4 4.4 4.5 10.6 11.1 3.2 1.0 5.4 4.9 0.3 2.6 5.3 1.2 1.6 5.3 2.0 3.2 2.4 4.2 2.3 10.9 0.4 7.0 2.2 4.8 2.1 1.1 0.1 4.7 0.4 1.3 7.4 0.2 1.6 0.9 5.9 0.2 0.0 0.0 0.1 0.0 0.2 1.1 0.1 5.4 1.3 0.9 0.0 0.1 0.0 0.7 0.7 11.5 0.0 0.0 0.0 2.3 5.0 0.0 5.1 0.1 4.3 1.6 0.0 0.0 0.1 0.0 2.7 0.1 2.3 0.0 0.0 0.0 1.9 4.5 0.0 0.0 0.2 0.0 0.0 0.1 0.1 3.0 15.9 0.0 4.9 0.1 0.2 0.0 0.5 0.6 0.0 0.7 1.1 0.9 1.0 0.1 0.0 2.6 0.1 0.4 0.0 2.0 17.4 0.0 0.0 2.9 0.0 0.0 3.3 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 1.1 1.0 0.0 0.0 1.1 4.5 7.0 5.0 4.8 4.4 4.5 5.4 4.9 5.3 4.8 4.7 5.9 1.1 0.0 0.0 4.9 0.0 0.0 0.7 0.7 0.6 0.0 1.4 1.1 17.4 0.0 0.4 0.0 2.1 0.2 0.1 1.8 3.9 4.5 0.3 3.6 0.5 0.7 4.2 0.0 0.0 2.2 0.2 0.6 0.0 0.9 0.0 0.1 2.5 4.9 1.7 0.0 0.1 6.0 0.0 3.1 0.4 0.0 0.3 1.6 0.0 0.0 2.0 8.2 0.0 3.5 13.3 0.8 8.5 0.0 0.0 0.4 8.5 12.9 2.2 0.2 0.0 2.1 1.2 0.0 0.0 0.2 0.0 0.0 0.2 0.3 5.0 0.5 DDX49 "Dbp8, FLJ10432" ENSG00000105671 "DEAD-box helicase 49" Q9Y6V7 19 18919705-18929189 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 103.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041870, HPA048093" Enhanced Approved Mitochondria NA NA "Cluster 44: Non-specific - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA041870: AB_2677717, HPA048093: AB_2680262" "unprognostic (3.51e-1)" "prognostic favorable (2.01e-6)" "unprognostic (2.28e-2)" "unprognostic (1.28e-1)" "unprognostic (8.56e-2)" "unprognostic (1.60e-2)" "prognostic unfavorable (7.05e-4)" "unprognostic (4.12e-2)" "unprognostic (2.41e-3)" "unprognostic (8.67e-2)" "unprognostic (6.46e-3)" "unprognostic (5.13e-2)" "prognostic unfavorable (7.44e-5)" "unprognostic (3.93e-2)" "unprognostic (2.99e-2)" "unprognostic (4.97e-2)" "unprognostic (3.24e-1)" 16.5 17.7 17.1 13.9 17.3 23.3 15.5 17.9 22.1 16.0 14.0 17.4 15.7 15.9 5.9 25.9 13.9 7.9 18.2 18.2 16.5 15.6 24.9 13.7 16.1 17.1 16.0 14.6 20.1 12.6 11.3 13.4 16.7 16.4 7.4 4.8 18.0 10.8 33.6 27.1 14.8 9.9 17.7 16.1 15.7 19.2 17.3 14.1 13.6 13.6 10.3 17.5 17.5 19.3 46.5 47.4 19.0 61.3 28.1 21.1 71.0 29.2 19.8 50.9 40.1 54.6 45.8 60.6 86.7 29.1 16.1 39.4 42.9 39.8 14.8 18.9 110.5 29.9 49.9 48.6 63.5 77.5 40.1 44.4 35.9 40.7 41.9 14.4 23.3 46.9 58.2 43.1 18.2 104.4 56.6 37.9 62.7 50.3 112.8 62.8 31.5 65.9 27.4 28.2 67.2 69.7 38.2 36.6 48.2 9.8 39.2 37.6 29.5 24.3 27.9 92.0 48.7 55.5 73.0 57.1 31.1 88.8 39.3 17.1 21.9 16.7 14.8 26.2 12.0 9.1 11.0 11.1 31.1 9.8 10.9 12.1 8.6 19.5 18.1 13.7 18.0 12.7 17.1 17.3 17.9 22.1 18.2 16.5 17.1 16.0 16.7 17.7 17.3 19.3 15.6 3.2 10.0 4.9 20.5 22.6 18.7 28.0 14.8 19.5 25.2 29.1 13.8 27.1 20.5 18.4 4.2 46.5 27.0 48.0 37.2 35.0 37.2 18.8 26.5 15.3 25.8 18.3 7.4 52.2 50.3 19.0 19.4 24.7 18.4 25.1 7.5 14.8 33.5 10.1 7.6 31.5 30.5 21.0 22.0 103.0 21.5 18.8 26.6 4.7 28.5 18.3 29.9 6.0 8.2 29.8 30.7 19.9 29.5 21.5 48.0 25.0 12.5 24.1 19.7 21.1 26.9 33.4 31.8 29.5 28.3 42.1 20.8 38.1 39.4 21.5 DEF6 "IBP, SLAT, SWAP70L" ENSG00000023892 "DEF6 guanine nucleotide exchange factor" Q9H4E7 6 35297818-35321771 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 63.2;lymphoid tissue: 62.9" "Cell type enhanced" "Detected in many" "Hofbauer cells: 94.0;Late spermatids: 151.4;NK-cells: 88.6;T-cells: 78.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "JURKAT: 83.3;MOLT-4: 75.5;NB-4: 99.3;REH: 68.8;THP-1: 78.9;U-937: 117.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA038975, HPA038976" Enhanced Enhanced Nucleoplasm Yes NA "Cluster 5: Granulocytes - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm "HPA038975: AB_10697544, HPA038976: AB_10673409" "prognostic favorable (3.02e-6)" "prognostic favorable (1.08e-4)" "prognostic unfavorable (1.71e-4)" "prognostic favorable (2.37e-4)" "unprognostic (1.93e-1)" "unprognostic (3.63e-3)" "unprognostic (2.24e-1)" "unprognostic (1.53e-2)" "unprognostic (1.64e-1)" "unprognostic (2.12e-1)" "unprognostic (2.14e-1)" "unprognostic (6.21e-3)" "prognostic unfavorable (1.02e-8)" "unprognostic (1.78e-1)" "unprognostic (2.91e-2)" "unprognostic (1.38e-1)" "unprognostic (1.45e-3)" 5.8 3.6 5.9 33.5 5.9 63.2 6.0 6.3 7.2 8.0 7.3 9.8 10.2 2.8 8.5 28.2 4.4 7.2 2.6 5.9 6.6 4.7 5.2 14.7 48.6 8.7 7.0 3.1 21.6 1.3 8.3 7.7 8.0 21.0 7.4 2.2 15.8 4.8 1.7 28.5 30.7 3.5 7.7 62.9 16.3 26.7 8.1 50.2 8.3 1.1 38.1 10.2 16.5 8.8 24.0 0.0 0.8 0.6 0.1 0.3 29.0 2.6 3.6 0.6 0.7 1.5 10.0 28.1 8.3 1.3 0.1 15.5 0.0 19.6 0.4 1.0 1.1 31.7 0.4 12.6 0.7 57.5 40.0 4.5 24.6 0.3 22.0 0.1 0.0 83.3 14.3 65.7 0.1 12.3 75.5 99.3 1.3 3.0 2.8 68.8 0.6 38.4 2.5 17.8 0.4 0.2 2.1 5.8 5.5 1.1 15.9 78.9 3.8 0.3 0.6 0.1 0.3 37.2 37.1 23.3 0.0 117.7 0.2 49.2 39.5 119.7 78.6 29.7 62.4 34.2 63.3 76.8 55.2 31.3 65.1 65.2 69.3 72.9 27.8 36.6 73.1 64.3 5.9 5.9 6.3 7.2 5.9 6.6 8.7 7.0 8.0 7.7 8.1 8.8 1.7 6.4 8.0 1.3 49.2 11.9 16.9 15.0 20.5 2.5 5.4 7.2 0.8 2.8 8.2 5.5 0.0 25.0 52.3 4.2 0.0 0.9 56.3 2.2 0.8 3.1 4.2 6.7 2.0 10.0 17.2 2.2 26.0 3.0 17.7 1.5 2.9 0.9 94.0 3.3 1.0 9.9 2.0 28.0 26.4 151.4 2.8 31.7 7.2 17.8 30.0 0.8 88.6 0.5 0.5 8.0 8.9 1.9 57.9 6.0 3.1 0.3 5.8 1.7 0.0 0.6 1.2 40.0 0.9 20.0 11.8 12.6 78.3 1.0 9.1 13.0 DHCR7 SLOS ENSG00000172893 "7-dehydrocholesterol reductase" Q9UBM7 11 71428193-71452868 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 161.1" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 77.9;Granulosa cells: 81.3;Hepatocytes: 156.1;Theca cells: 103.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044280 Approved Supported "Endoplasmic reticulum" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum" "HPA044280: AB_10794893" "unprognostic (1.76e-1)" "unprognostic (1.50e-3)" "unprognostic (1.32e-2)" "unprognostic (7.16e-3)" "unprognostic (2.69e-1)" "unprognostic (2.18e-3)" "unprognostic (8.57e-3)" "unprognostic (3.02e-2)" "unprognostic (4.91e-2)" "unprognostic (1.13e-1)" "unprognostic (1.08e-2)" "unprognostic (5.45e-2)" "prognostic favorable (6.93e-7)" "unprognostic (1.73e-1)" "unprognostic (1.01e-1)" "unprognostic (8.15e-2)" "prognostic unfavorable (5.67e-4)" 23.7 97.2 28.1 13.0 35.4 46.7 36.3 42.4 37.0 16.2 15.6 21.1 48.1 10.6 59.2 42.2 12.5 8.9 28.8 28.8 35.8 16.3 161.1 21.8 6.0 55.3 38.8 54.4 16.6 24.4 18.4 8.3 55.8 21.6 14.4 8.7 27.8 7.1 13.6 68.2 19.3 9.9 34.4 9.6 19.1 31.0 38.0 4.7 11.9 13.2 9.4 7.9 22.7 58.9 126.4 112.3 106.7 118.9 49.0 75.8 33.7 50.9 134.1 43.1 114.5 419.8 401.5 87.1 79.0 48.6 376.2 235.9 128.8 276.7 44.5 33.5 98.7 33.4 89.3 183.1 127.8 63.7 15.6 89.2 122.1 159.3 108.4 34.6 63.8 112.7 159.6 180.7 43.2 341.1 52.4 72.6 154.1 124.9 67.4 46.9 150.6 377.3 162.3 187.3 144.7 53.9 48.4 157.6 113.9 51.4 153.2 34.5 60.4 11.5 62.4 3.7 61.5 59.3 78.7 95.8 33.8 110.9 48.9 5.6 2.1 1.9 10.5 1.4 12.6 6.5 8.9 9.8 2.8 5.4 11.0 13.0 1.1 5.8 1.5 7.1 6.0 6.9 28.1 35.4 42.4 37.0 28.8 35.8 55.3 38.8 55.8 34.4 38.0 58.9 7.1 3.2 19.1 7.2 7.1 0.8 10.1 77.9 3.4 8.4 21.8 14.9 13.1 15.7 39.2 22.0 12.5 15.5 11.9 9.9 7.9 36.9 0.1 3.9 1.5 11.8 9.5 5.2 3.2 49.9 27.6 12.8 11.7 9.3 0.0 81.3 7.9 156.1 11.9 0.0 4.5 12.3 54.9 3.8 3.3 1.7 8.4 5.6 5.4 1.0 5.8 21.2 4.1 5.0 14.7 26.7 11.5 4.9 10.0 16.5 8.9 3.8 7.6 8.7 13.1 3.9 9.0 0.5 7.0 11.9 1.1 54.2 13.8 103.6 15.0 9.5 DHRS2 "HEP27, SDR25C1" ENSG00000100867 "Dehydrogenase/reductase 2" Q13268 14 23630115-23645639 "Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 336.3;urinary bladder: 392.6" "Cell type enhanced" "Detected in some" "Extravillous trophoblasts: 15.1;Syncytiotrophoblasts: 24.8;Theca cells: 12.6;Urothelial cells: 30.6" "Cancer enriched" "Detected in many" 6 "urothelial cancer: 141.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 719.8;RT4: 828.1;SK-BR-3: 4047.2;U-2 OS: 1286.3" "Region enriched" "Detected in single" 4 "cerebellum: 2.4" "HPA053915, HPA069551" Enhanced Supported Nucleoplasm,Mitochondria No NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Mitochondria Nucleoplasm "HPA053915: AB_2682307, HPA069551: AB_2686150" "unprognostic (3.07e-1)" "unprognostic (4.91e-2)" "unprognostic (3.44e-2)" "prognostic unfavorable (3.23e-4)" "unprognostic (9.97e-2)" "unprognostic (5.03e-3)" "unprognostic (5.62e-2)" "unprognostic (1.86e-1)" "unprognostic (4.08e-1)" "unprognostic (6.91e-2)" "unprognostic (6.66e-2)" "unprognostic (4.59e-2)" "prognostic unfavorable (3.75e-5)" "unprognostic (1.83e-1)" "unprognostic (1.46e-1)" "unprognostic (1.76e-1)" "prognostic favorable (6.45e-4)" 1.2 1.6 0.3 0.1 0.2 0.0 336.3 0.2 0.4 1.9 0.2 0.2 0.0 0.2 0.4 0.1 0.3 0.0 0.0 0.4 1.2 1.6 23.6 0.2 0.0 0.4 1.2 25.5 10.3 2.1 2.5 3.2 1.7 3.3 0.4 0.4 97.7 3.1 0.0 3.4 0.1 0.2 0.3 19.0 4.7 3.4 1.1 0.0 0.1 0.0 0.0 392.6 13.6 0.3 1.2 2.2 0.2 199.9 0.3 0.3 3.1 0.3 0.2 6.4 0.1 14.4 1.1 0.8 1.9 0.3 10.4 2.0 0.7 1.2 1.4 289.5 21.6 2.8 1.0 719.8 0.0 4.3 25.1 1.7 0.2 2.5 1.7 0.0 0.1 0.4 1.8 0.7 1.4 8.0 2.5 0.3 1.1 6.9 31.7 2.6 6.3 2.7 0.0 828.1 3.5 5.0 5.9 4047.2 4.9 0.7 3.9 1.0 0.0 2.4 1286.3 7.7 4.3 2.0 0.6 11.3 1.7 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.2 0.4 0.4 1.2 0.4 1.2 1.7 0.3 1.1 0.3 0.1 0.0 0.0 0.0 0.4 0.0 2.1 0.2 0.0 0.8 7.4 1.3 0.4 0.0 0.0 0.0 0.0 7.9 0.1 0.1 7.9 0.1 5.0 0.1 0.0 0.2 3.5 0.0 0.1 0.2 15.1 3.5 0.0 0.0 0.0 1.4 0.0 4.9 1.7 0.0 0.1 0.2 0.0 0.3 0.8 3.7 0.0 0.1 0.0 0.0 0.6 0.4 0.0 0.0 0.0 4.8 0.2 1.2 0.0 0.3 0.0 0.2 0.0 1.2 6.6 0.0 0.7 0.3 7.4 0.0 0.1 24.8 0.2 12.6 0.7 30.6 DIP2B "FLJ34278, KIAA1463" ENSG00000066084 "Disco interacting protein 2 homolog B" Q9P265 12 50504985-50748657 "Human disease related genes, Predicted intracellular proteins" Neurogenesis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 61.4" "Cell type enhanced" "Detected in many" "Microglial cells: 188.3;Oligodendrocyte precursor cells: 144.8;Oligodendrocytes: 634.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038472, HPA046133, HPA056045" Enhanced Approved "Endoplasmic reticulum" No No "Cluster 14: Monocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 1: K-562 - Erythropoiesis" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Endoplasmic reticulum" "HPA038472: AB_2676033, HPA046133: AB_2679551, HPA056045: AB_2683019" "prognostic unfavorable (2.60e-4)" "unprognostic (2.85e-2)" "unprognostic (3.67e-3)" "unprognostic (2.86e-2)" "unprognostic (9.56e-2)" "unprognostic (2.45e-1)" "unprognostic (1.69e-2)" "unprognostic (3.90e-2)" "unprognostic (1.94e-2)" "unprognostic (2.67e-2)" "unprognostic (9.57e-3)" "unprognostic (3.90e-2)" "unprognostic (4.29e-2)" "unprognostic (7.99e-2)" "unprognostic (1.82e-1)" "unprognostic (1.60e-2)" "unprognostic (1.70e-3)" 6.6 8.7 22.8 8.9 46.0 12.1 10.5 35.0 28.2 7.1 6.9 9.5 6.2 6.2 3.4 14.6 4.3 7.0 5.7 22.5 31.0 6.0 11.3 6.7 9.9 36.1 40.0 9.3 7.6 11.0 6.1 10.3 38.0 6.5 10.7 16.4 8.5 4.1 5.1 17.3 6.5 7.1 26.4 14.9 6.9 7.6 37.0 12.9 8.2 6.3 11.7 7.3 8.8 61.4 20.0 12.0 17.9 12.6 10.0 9.7 25.0 11.3 13.1 10.6 8.0 21.8 11.0 13.4 13.4 12.4 10.9 20.5 28.8 21.1 12.6 15.9 10.7 21.3 10.1 27.6 15.7 25.7 12.4 11.0 18.1 11.8 17.1 18.6 20.4 12.0 30.3 12.5 9.4 15.7 19.9 12.9 10.2 11.4 22.0 23.4 17.6 6.4 12.0 15.5 16.9 11.8 28.3 16.4 17.3 20.6 23.0 17.7 21.6 8.6 10.1 7.9 9.3 9.0 16.0 15.4 11.9 11.7 12.0 1.0 1.2 2.7 0.4 1.4 0.6 1.4 0.9 0.3 1.4 2.2 1.6 1.3 4.9 0.5 3.9 0.4 1.0 0.7 22.8 46.0 35.0 28.2 22.5 31.0 36.1 40.0 38.0 26.4 37.0 61.4 15.4 6.4 10.5 74.1 26.3 54.9 30.2 14.7 12.5 31.5 15.0 11.4 9.0 17.2 10.5 9.2 64.6 13.3 9.2 25.2 0.0 10.9 1.4 14.3 12.9 15.5 31.3 13.7 121.1 17.4 17.6 11.2 20.4 15.1 10.8 25.0 15.0 18.2 20.4 11.8 125.3 18.3 10.2 37.4 15.7 3.3 10.2 24.5 16.0 188.3 18.7 14.4 11.3 144.8 634.8 22.0 14.0 10.1 15.4 28.1 8.4 6.7 8.8 31.9 0.0 8.0 10.0 12.4 17.7 34.6 66.9 38.0 13.3 34.3 12.4 24.4 DIPK2B "CXorf36, DIA1R, FLJ14103" ENSG00000147113 "Divergent protein kinase domain 2B" Q9H7Y0 X 45148373-45200901 "Disease related genes, Predicted secreted proteins" "Autism, Autism spectrum disorder" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 4 "Adipocytes: 96.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 57 "HUVEC TERT2: 81.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA002806 Uncertain "Secreted - unknown location" NA NA 940000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA002806: AB_1078595" "unprognostic (2.12e-1)" "unprognostic (1.32e-2)" "unprognostic (8.51e-3)" "unprognostic (2.05e-1)" "unprognostic (4.65e-2)" "unprognostic (4.07e-3)" "unprognostic (7.30e-2)" "unprognostic (1.61e-1)" "unprognostic (1.50e-1)" "unprognostic (3.39e-1)" "unprognostic (6.06e-2)" "unprognostic (1.32e-1)" "unprognostic (1.75e-3)" "unprognostic (3.79e-3)" "unprognostic (1.98e-1)" "unprognostic (8.47e-2)" "unprognostic (3.11e-2)" 40.8 5.3 14.4 6.1 15.0 0.8 36.9 11.7 13.9 19.6 7.8 9.1 2.6 20.5 6.9 6.5 18.0 8.8 27.3 11.4 13.1 7.0 1.4 14.1 5.7 14.4 14.2 6.9 3.5 4.6 3.3 40.5 14.1 11.3 3.8 1.4 6.8 7.2 16.6 7.4 7.7 20.7 12.4 3.1 6.3 1.5 14.8 2.7 18.5 16.6 3.4 14.3 13.9 15.4 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.3 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.1 81.7 0.1 0.0 0.5 0.0 0.1 0.0 0.3 0.1 1.4 0.5 0.1 0.1 0.1 0.1 0.1 0.3 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.5 0.1 0.1 0.0 0.0 0.3 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 14.4 15.0 11.7 13.9 11.4 13.1 14.4 14.2 14.1 12.4 14.8 15.4 96.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 23.3 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 DNAAF3 "C19orf51, CILD2, FLJ36139, FLJ40069, PCD, PF22" ENSG00000167646 "Dynein axonemal assembly factor 3" Q8N9W5 19 55158661-55166722 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "fallopian tube: 40.8;testis: 65.4" "Group enriched" "Detected in many" 5 "Early spermatids: 395.2;Late spermatids: 722.0" "Cancer enhanced" "Detected in many" "endometrial cancer: 4.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEK 293: 26.2;HEL: 31.6;K-562: 25.3;U-937: 18.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA056220 Approved "Nuclear bodies,Mitochondria" No No "Cluster 49: Ciliated cells - Cilium organization" "Cluster 36: HEL - Hemostasis" "Cluster 31: Spermatids - Spermatogenesis" Mitochondria "Nuclear bodies" "HPA056220: AB_2683071" "unprognostic (1.71e-2)" "unprognostic (2.67e-2)" "unprognostic (6.10e-2)" "unprognostic (9.93e-3)" "unprognostic (1.77e-1)" "unprognostic (1.87e-1)" "unprognostic (2.22e-2)" "unprognostic (1.82e-1)" "unprognostic (5.36e-2)" "unprognostic (2.26e-1)" "unprognostic (2.15e-1)" "unprognostic (1.68e-1)" "prognostic unfavorable (1.83e-5)" "unprognostic (1.35e-2)" "unprognostic (1.31e-1)" "unprognostic (2.35e-2)" "unprognostic (8.03e-2)" 0.4 1.8 1.5 0.0 1.2 0.0 0.6 0.9 0.7 2.5 6.1 0.3 0.1 0.9 3.4 0.6 40.8 0.6 5.0 1.5 2.3 2.7 0.6 4.3 0.1 4.0 8.2 0.2 1.6 3.5 0.7 0.1 4.7 0.3 0.1 0.4 0.4 0.9 0.1 0.9 0.3 0.2 3.1 0.3 0.3 65.4 1.5 0.5 2.3 0.0 0.1 0.1 0.4 2.1 8.8 6.6 0.6 6.7 0.1 0.0 0.6 0.1 0.2 1.0 0.7 0.3 4.0 10.5 2.5 0.3 1.9 10.1 1.5 3.0 0.4 0.0 26.2 31.6 0.5 0.5 0.2 13.6 3.1 0.2 4.0 1.7 2.2 0.9 0.5 4.7 25.3 13.9 0.4 5.9 0.4 0.3 0.5 9.5 15.0 16.5 1.0 3.2 5.4 0.2 0.8 2.6 1.1 1.1 1.6 0.2 8.3 0.4 1.0 0.8 3.9 4.0 0.2 0.4 2.5 0.6 4.9 18.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.5 1.2 0.9 0.7 1.5 2.3 4.0 8.2 4.7 3.1 1.5 2.1 0.2 0.0 0.5 0.0 0.0 3.2 0.0 4.7 4.6 0.0 1.1 0.6 3.0 1.5 7.5 7.3 0.0 0.0 0.0 0.3 7.9 2.7 395.2 55.8 0.5 0.6 0.0 0.0 0.5 1.0 0.1 1.2 0.0 1.3 0.0 1.9 0.7 0.4 0.2 0.0 0.5 0.5 12.2 0.0 0.4 722.0 4.4 4.2 0.0 0.0 0.0 2.1 0.0 0.5 0.1 0.2 0.1 3.0 0.0 0.1 0.0 5.1 75.2 0.0 0.0 0.0 2.3 104.8 18.6 0.3 1.3 0.0 0.1 1.1 0.4 0.2 DTL "CDT2, DCAF2, L2DTL, RAMP" ENSG00000143476 "Denticleless E3 ubiquitin protein ligase homolog" Q9NZJ0 1 212035553-212107400 "Predicted intracellular proteins" "Biological rhythms, DNA damage, DNA replication, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 14.6;intestine: 4.7;lymphoid tissue: 14.2;placenta: 3.9;testis: 13.7" "Cell type enhanced" "Detected in many" "Early spermatids: 25.3;Erythroid cells: 36.2;Extravillous trophoblasts: 16.2;Spermatocytes: 53.2;Spermatogonia: 20.8" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "T-reg: 2.0" "Lineage enriched" "Detected in single" 8 "T-cells: 2.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA028016, HPA032023, HPA032031" Supported Supported Nucleoplasm,Nucleoli,Cytosol Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nucleoli, Cytosol" "HPA028016: AB_10611958, HPA032023: AB_2674114, HPA032031: AB_2674119" "unprognostic (7.61e-2)" "unprognostic (1.01e-3)" "unprognostic (2.14e-2)" "unprognostic (3.05e-2)" "unprognostic (2.19e-1)" "unprognostic (5.31e-2)" "prognostic unfavorable (4.41e-5)" "unprognostic (8.96e-3)" "unprognostic (2.45e-3)" "unprognostic (8.83e-3)" "unprognostic (2.52e-3)" "unprognostic (2.83e-2)" "prognostic unfavorable (1.71e-9)" "unprognostic (5.93e-2)" "unprognostic (2.01e-1)" "unprognostic (1.96e-2)" "unprognostic (2.82e-1)" 0.6 0.2 0.0 4.1 0.0 14.6 1.9 0.0 0.1 0.6 0.0 3.3 2.3 1.1 0.1 1.9 0.4 0.4 0.1 0.0 0.0 0.1 1.2 1.4 5.6 0.0 0.1 0.1 0.1 0.5 0.2 3.9 0.0 0.4 4.7 0.0 0.4 0.1 0.1 2.1 3.0 1.9 0.0 2.5 1.3 13.7 0.1 14.2 0.5 0.0 6.4 1.2 0.7 0.0 34.1 28.1 48.0 23.6 2.9 5.8 23.3 41.3 25.5 38.1 56.1 17.6 29.0 25.2 15.4 16.1 25.0 25.8 62.5 34.9 54.7 31.4 30.9 40.7 33.6 21.5 0.1 54.1 25.3 2.5 1.2 62.2 32.4 6.8 17.7 44.7 49.1 51.1 44.4 13.5 75.3 24.3 56.6 25.2 32.9 57.2 84.0 49.2 11.6 22.9 29.6 46.0 39.2 37.5 17.6 47.7 32.0 24.1 9.7 38.2 28.6 40.5 47.8 18.4 30.5 57.7 19.1 35.5 37.8 0.0 0.0 0.0 0.2 0.2 0.0 0.2 0.3 0.5 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 2.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.0 2.3 2.3 0.4 1.7 0.0 0.0 1.3 1.3 7.0 1.5 0.9 0.0 0.0 12.8 1.4 1.5 0.0 0.4 25.3 0.4 1.3 5.2 0.0 36.2 0.2 0.0 16.2 2.4 3.1 1.0 0.0 11.4 0.7 0.4 4.7 0.0 0.3 3.3 0.0 0.3 0.8 12.4 1.2 2.2 0.0 1.0 0.2 0.0 0.0 0.0 0.1 0.6 0.4 0.0 12.8 0.2 0.6 0.0 0.1 0.0 0.0 0.2 2.7 53.2 20.8 5.6 1.7 1.5 2.6 1.6 5.2 0.7 DTWD1 "MDS009, MGC111207" ENSG00000104047 "DTW domain containing 1" Q8N5C7 15 49621037-49656232 "Enzymes, Predicted intracellular proteins" "tRNA processing" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042214 Uncertain Approved "Nucleoplasm,Nucleoli rim,Mitotic chromosome,Vesicles" Yes No "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "Nucleoli rim" "Nucleoplasm, Mitotic chromosome, Vesicles" "HPA042214: AB_2677903" "unprognostic (2.60e-2)" "unprognostic (1.73e-1)" "unprognostic (3.00e-1)" "unprognostic (3.70e-4)" "unprognostic (8.12e-2)" "unprognostic (2.37e-1)" "unprognostic (1.82e-1)" "unprognostic (9.87e-2)" "unprognostic (4.44e-3)" "unprognostic (4.25e-2)" "unprognostic (5.42e-2)" "unprognostic (1.48e-1)" "unprognostic (2.32e-3)" "unprognostic (1.02e-1)" "unprognostic (7.85e-2)" "unprognostic (2.80e-2)" "unprognostic (2.35e-1)" 19.6 11.8 7.7 13.0 10.1 5.4 18.2 8.2 9.1 27.4 6.5 21.1 7.4 22.6 16.8 13.3 21.1 23.0 11.0 9.0 8.9 11.0 11.5 10.9 12.9 5.7 6.9 22.7 33.3 11.5 9.2 12.8 6.0 15.7 11.9 8.8 21.5 14.7 10.3 12.2 9.1 20.5 6.4 9.0 14.9 9.5 9.9 11.7 17.6 21.1 10.0 20.4 15.9 9.8 10.0 11.9 21.2 11.5 41.3 84.1 16.6 29.3 28.6 36.8 27.5 4.2 8.3 16.7 20.3 38.7 16.8 17.8 15.6 15.8 37.7 10.8 11.2 13.8 23.5 14.5 29.1 18.0 11.1 38.8 20.4 24.3 29.7 32.9 15.5 19.3 26.3 17.3 41.7 23.3 12.3 15.1 12.4 22.6 15.7 17.4 44.7 64.9 12.3 7.1 18.6 14.4 34.7 11.5 27.3 22.1 12.1 25.4 10.7 43.6 17.3 25.6 32.3 13.2 22.2 10.0 37.5 53.9 28.3 8.7 9.7 5.2 6.8 11.7 9.8 9.7 10.3 11.6 12.8 10.1 12.0 11.5 2.6 13.9 15.3 25.3 8.9 6.0 7.7 10.1 8.2 9.1 9.0 8.9 5.7 6.9 6.0 6.4 9.9 9.8 39.9 19.2 15.0 36.6 16.6 19.2 15.4 31.9 18.2 41.8 23.0 34.0 18.8 12.8 22.1 35.0 31.3 23.4 27.1 4.7 31.3 20.1 21.0 27.8 88.1 23.6 15.5 20.8 57.2 21.0 27.7 49.9 20.4 14.1 7.0 29.3 25.4 14.9 19.5 18.5 55.2 19.2 40.7 16.4 14.9 11.2 37.9 16.7 16.0 18.7 10.4 20.3 18.6 33.7 66.1 20.8 10.3 28.2 27.0 21.5 9.5 22.0 37.9 40.0 6.6 35.5 46.7 51.2 44.3 19.6 19.0 9.7 16.2 35.4 17.1 12.7 DTX2 "KIAA1528, RNF58" ENSG00000091073 "Deltex E3 ubiquitin ligase 2" Q86UW9 7 76461676-76505995 "Enzymes, Predicted intracellular proteins" "Notch signaling pathway, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 54.0" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 87.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "A549: 67.7;CAPAN-2: 110.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042931 Approved Supported "Nucleoplasm,Nuclear membrane" NA Yes "Cluster 8: Neutrophils - Inflammatory response" "Cluster 71: Testis - DNA repair" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Nuclear membrane" "HPA042931: AB_2678227" "unprognostic (1.72e-1)" "unprognostic (1.73e-1)" "unprognostic (1.62e-2)" "unprognostic (1.58e-2)" "prognostic unfavorable (8.47e-4)" "unprognostic (2.85e-2)" "unprognostic (1.28e-3)" "unprognostic (7.54e-2)" "unprognostic (4.76e-2)" "unprognostic (2.28e-2)" "unprognostic (2.10e-2)" "unprognostic (6.56e-2)" "prognostic unfavorable (1.13e-8)" "unprognostic (2.87e-2)" "unprognostic (1.53e-1)" "unprognostic (1.50e-1)" "unprognostic (1.19e-2)" 10.0 5.0 5.6 12.3 6.3 5.1 10.3 3.3 10.1 17.4 13.8 15.8 10.2 9.3 1.1 54.0 10.5 9.3 6.8 4.3 5.9 5.4 8.7 10.3 10.9 11.1 8.1 8.1 10.5 8.4 6.7 5.3 8.1 13.7 8.1 4.4 30.4 3.9 12.5 31.0 13.3 4.3 3.8 13.3 14.2 28.1 13.5 9.0 7.9 2.7 10.1 12.1 27.2 12.8 31.8 67.7 9.9 14.7 5.5 5.4 21.2 6.8 5.7 7.2 9.9 19.1 110.9 9.8 4.7 6.8 38.1 23.2 5.3 32.1 4.5 22.1 11.3 5.6 14.4 16.9 7.4 8.2 13.7 9.6 19.1 18.7 10.0 5.6 5.5 17.2 17.3 14.3 8.8 15.3 12.6 28.6 14.4 23.8 10.2 13.8 9.1 17.7 3.4 24.4 3.9 8.2 10.9 18.4 9.3 8.6 18.5 21.6 5.8 40.5 19.0 13.8 27.1 10.7 13.7 11.2 8.8 8.8 21.3 17.7 11.6 17.2 8.6 13.3 6.2 6.6 7.1 8.5 10.1 7.3 7.1 7.9 22.8 4.2 18.8 17.8 11.0 8.4 5.6 6.3 3.3 10.1 4.3 5.9 11.1 8.1 8.1 3.8 13.5 12.8 7.3 6.4 5.0 5.2 13.1 33.9 19.5 87.2 23.3 2.6 7.1 4.8 2.3 4.3 59.2 7.3 8.4 18.5 12.0 39.1 3.9 19.4 33.0 8.1 3.1 5.9 9.1 3.8 5.7 10.8 13.5 6.5 61.2 10.7 3.8 3.2 7.1 4.3 21.6 3.3 5.2 25.6 22.4 11.0 7.7 10.4 5.6 14.5 7.2 19.7 10.0 5.7 8.2 18.1 10.0 23.1 37.9 4.9 13.9 20.0 21.0 3.2 62.8 9.2 6.6 3.0 7.3 11.0 11.0 27.0 35.4 37.6 9.7 1.9 26.1 62.5 DTX4 "KIAA0937, RNF155" ENSG00000110042 "Deltex E3 ubiquitin ligase 4" Q9Y2E6 11 59171430-59208588 "Enzymes, Predicted intracellular proteins" "Notch signaling pathway, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 50.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 33.6;Oligodendrocytes: 33.9" "Cancer enhanced" "Detected in all" "thyroid cancer: 63.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 2.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 62.8;CACO-2: 34.5;CAPAN-2: 37.7;OE19: 35.4;RT4: 95.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056760, HPA059294" Approved Approved Vesicles NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA056760: AB_2683228, HPA059294: AB_2683969" "unprognostic (3.23e-2)" "unprognostic (1.57e-1)" "unprognostic (1.10e-2)" "unprognostic (4.98e-2)" "unprognostic (4.97e-2)" "unprognostic (5.03e-1)" "unprognostic (2.92e-1)" "unprognostic (1.06e-1)" "unprognostic (3.75e-1)" "unprognostic (1.14e-1)" "unprognostic (5.69e-2)" "unprognostic (3.04e-1)" "prognostic unfavorable (8.94e-4)" "unprognostic (5.51e-2)" "unprognostic (2.51e-1)" "prognostic favorable (5.81e-4)" "unprognostic (2.57e-3)" 10.4 1.9 13.9 5.5 21.2 9.3 9.5 21.4 20.0 8.0 8.2 17.5 16.4 3.8 1.9 4.7 5.8 4.9 3.2 13.2 21.2 8.5 32.5 18.1 5.3 30.2 22.4 15.0 7.9 1.0 4.1 14.8 27.0 7.5 17.2 10.4 21.7 3.1 1.4 3.9 14.4 2.5 33.5 6.7 11.6 1.7 25.6 1.5 10.2 1.7 6.5 15.0 3.9 50.5 4.8 5.7 30.5 0.6 8.5 0.5 62.8 0.4 2.7 0.3 0.4 34.5 37.7 11.6 2.1 0.7 1.2 16.5 9.5 11.8 0.1 0.8 0.5 0.1 6.6 11.2 2.4 0.9 2.3 1.4 19.3 0.1 0.5 2.1 0.0 2.1 0.1 1.1 1.4 2.7 0.5 0.1 16.1 35.4 1.5 4.1 27.1 1.3 2.6 95.2 0.0 0.1 24.3 6.4 0.8 7.7 4.9 0.5 0.3 0.1 4.9 0.1 0.0 0.4 0.1 1.1 0.2 2.8 2.6 0.7 0.4 0.4 0.0 0.4 0.0 1.0 0.0 0.0 0.6 1.3 0.0 0.0 1.5 0.0 0.2 2.8 0.0 0.1 13.9 21.2 21.4 20.0 13.2 21.2 30.2 22.4 27.0 33.5 25.6 50.5 8.9 19.2 16.8 9.4 3.1 1.7 3.2 7.9 2.2 2.0 2.9 3.9 1.4 28.6 21.8 7.3 0.0 15.0 6.9 33.6 0.0 10.2 0.4 1.5 8.1 3.6 4.9 0.0 12.0 4.9 19.2 7.2 12.2 3.0 1.3 4.9 5.7 23.1 3.7 0.0 8.4 10.5 2.0 2.5 2.5 0.4 4.1 2.7 5.4 3.7 0.9 30.3 0.0 7.5 33.9 10.8 16.3 3.4 0.0 3.1 19.8 9.1 14.9 2.0 0.0 22.1 3.6 0.4 1.7 1.8 1.3 5.5 1.2 5.9 18.5 22.5 DUOX1 "LNOX1, NOXEF1, THOX1" ENSG00000137857 "Dual oxidase 1" Q9NRD9 15 45129933-45165576 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrogen peroxide, Thyroid hormones biosynthesis" "Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 108.5;skin 1: 81.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 83.3;Alveolar cells type 2: 168.6;Endometrial ciliated cells: 67.1;Glandular and luminal cells: 88.5;Respiratory ciliated cells: 64.9" "Cancer enhanced" "Detected in many" "thyroid cancer: 32.4" "Group enriched" "Detected in many" 6 "cerebellum: 12.4;white matter: 3.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HaCaT: 64.4;hTCEpi: 30.5;RT4: 36.3" "Not detected" "Not detected" "Region enriched" "Detected in some" 5 "cerebellum: 9.6" HPA023544 Approved NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "HPA023544: AB_1847878" "unprognostic (2.85e-2)" "prognostic favorable (4.31e-6)" "unprognostic (2.49e-2)" "unprognostic (8.84e-3)" "unprognostic (1.44e-2)" "unprognostic (3.27e-2)" "unprognostic (1.23e-1)" "unprognostic (2.57e-2)" "unprognostic (5.87e-2)" "unprognostic (6.02e-3)" "unprognostic (5.13e-2)" "unprognostic (1.19e-1)" "unprognostic (8.91e-3)" "unprognostic (2.23e-1)" "unprognostic (3.06e-2)" "unprognostic (1.14e-2)" "unprognostic (3.03e-1)" 1.5 14.1 0.7 1.0 1.0 0.2 4.5 12.4 1.2 44.5 0.0 1.0 0.6 3.0 50.0 108.5 14.0 3.3 3.3 1.0 0.3 0.7 0.4 70.1 0.3 0.3 0.3 1.8 0.5 5.2 1.3 1.5 0.6 13.8 0.3 0.6 18.7 13.0 0.4 81.7 0.7 0.4 0.1 0.3 64.3 1.6 0.4 1.1 70.4 0.0 14.7 11.1 42.0 3.2 8.3 0.1 0.5 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.2 0.0 0.0 64.4 0.0 6.1 0.0 0.8 0.4 0.0 0.9 0.1 0.0 0.0 0.3 0.0 30.5 0.0 1.9 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.3 0.0 1.2 0.1 0.0 0.0 36.3 0.8 1.5 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.1 0.2 0.0 0.0 0.1 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 1.0 12.4 1.2 1.0 0.3 0.3 0.3 0.6 0.1 0.4 3.2 0.9 83.3 168.6 4.2 4.5 11.1 14.3 22.8 11.4 21.3 4.7 2.8 2.4 8.6 32.5 3.7 8.4 5.3 7.6 2.5 0.0 3.8 0.7 67.1 9.4 3.8 21.7 2.7 5.1 5.4 0.6 5.1 17.9 88.5 8.2 7.9 7.9 1.5 1.2 6.7 3.9 4.0 16.2 3.1 43.5 0.3 3.4 3.3 16.0 1.0 3.2 3.5 33.0 9.5 10.6 4.7 4.0 3.8 0.1 9.5 6.8 0.5 64.9 4.4 0.0 8.5 4.7 11.5 7.5 36.4 18.0 3.7 4.5 0.4 5.6 30.0 DUS2 "DUS2L, FLJ20399, SMM1" ENSG00000167264 "Dihydrouridine synthase 2" Q9NX74 16 67987746-68079320 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Oxidoreductase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 118.1;Late spermatids: 94.1;Spermatocytes: 53.1;Syncytiotrophoblasts: 61.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042560, HPA043528" Enhanced Enhanced Cytosol NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "HPA042560: AB_10965170, HPA043528: AB_10959753" "unprognostic (2.21e-1)" "unprognostic (5.06e-2)" "unprognostic (1.91e-1)" "unprognostic (1.23e-2)" "unprognostic (8.12e-2)" "unprognostic (1.63e-2)" "unprognostic (1.23e-2)" "unprognostic (9.84e-2)" "unprognostic (2.36e-1)" "unprognostic (2.34e-1)" "unprognostic (1.53e-1)" "unprognostic (3.18e-1)" "prognostic favorable (3.50e-5)" "unprognostic (1.44e-2)" "unprognostic (8.05e-2)" "unprognostic (1.58e-1)" "unprognostic (1.81e-1)" 5.8 6.8 5.2 12.6 5.8 9.6 5.8 6.8 7.5 6.1 4.6 8.6 5.7 5.3 4.9 12.2 5.1 5.5 6.1 5.3 6.1 5.9 9.2 6.8 18.8 6.8 5.8 4.8 4.4 7.5 4.9 9.9 6.6 5.4 8.4 5.3 5.9 5.0 9.6 10.8 10.4 7.9 5.0 15.9 6.4 27.5 6.4 7.6 5.4 8.9 20.2 7.0 7.4 7.8 17.1 25.5 11.0 17.1 8.8 14.8 20.4 16.1 15.6 33.4 23.7 27.5 29.9 39.7 14.3 17.0 9.8 22.8 26.6 28.5 25.5 6.1 16.0 13.4 15.6 20.6 14.9 15.1 18.4 14.5 21.9 27.5 26.8 12.8 21.3 29.9 16.1 6.5 16.0 24.9 16.0 22.5 12.2 16.9 13.5 26.8 12.5 28.3 18.4 11.8 13.0 11.3 31.8 12.3 7.1 14.1 25.1 8.4 11.7 14.8 13.3 12.9 13.6 18.4 24.5 36.6 10.6 19.7 8.8 12.1 29.2 89.9 9.5 25.8 9.2 56.9 6.5 10.3 21.9 48.4 9.4 8.5 27.8 21.3 37.7 8.6 13.5 17.2 5.2 5.8 6.8 7.5 5.3 6.1 6.8 5.8 6.6 5.0 6.4 7.8 2.5 9.6 4.6 6.8 17.1 2.7 2.0 12.8 4.6 3.9 2.4 2.2 2.6 4.3 6.2 7.3 8.4 29.2 6.0 5.7 5.9 10.4 118.1 1.7 3.5 5.3 4.2 3.0 7.2 5.4 17.3 3.8 4.6 2.6 7.0 7.2 9.3 7.9 13.4 15.2 8.0 5.5 6.1 11.9 2.3 94.1 3.7 6.2 3.6 2.8 13.5 4.5 9.2 5.5 7.3 9.5 3.6 7.9 7.7 3.4 4.2 10.8 4.1 2.9 6.6 3.4 4.7 53.1 15.0 5.2 2.6 61.4 4.2 10.0 6.0 2.1 DUSP11 PIR1 ENSG00000144048 "Dual specificity phosphatase 11" O75319 2 73762184-73780157 "Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021052 Supported "Nucleoplasm,Nucleoli fibrillar center,Cytokinetic bridge" Yes Yes "Cluster 31: Non-specific - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Nucleoli fibrillar center" "Cytokinetic bridge" "HPA021052: AB_2670577" "unprognostic (2.45e-3)" "unprognostic (1.06e-1)" "unprognostic (2.19e-2)" "unprognostic (7.87e-3)" "unprognostic (9.14e-2)" "unprognostic (5.28e-3)" "prognostic unfavorable (2.10e-7)" "unprognostic (7.20e-2)" "unprognostic (5.43e-2)" "unprognostic (5.85e-2)" "unprognostic (8.67e-3)" "unprognostic (3.84e-2)" "unprognostic (7.56e-3)" "unprognostic (1.41e-1)" "unprognostic (1.47e-1)" "unprognostic (1.47e-3)" "unprognostic (1.46e-1)" 16.0 13.3 7.9 17.1 7.7 35.2 20.4 13.4 11.2 22.4 7.6 16.0 17.3 21.2 19.3 30.5 39.0 15.9 14.2 8.1 6.9 20.2 17.9 14.3 25.3 6.1 5.7 23.5 11.0 14.7 14.0 20.5 6.1 16.5 17.4 8.3 16.0 14.4 14.3 27.6 15.3 19.6 4.8 19.0 16.3 16.8 6.5 24.8 16.5 17.8 26.1 25.2 22.4 8.3 39.4 16.7 17.6 18.6 31.2 38.7 31.2 28.2 36.7 35.8 36.4 24.2 29.1 50.6 17.7 30.6 32.1 26.7 22.0 56.8 34.3 35.2 22.9 31.2 12.0 37.3 32.7 35.5 28.0 31.6 67.3 32.1 44.1 31.1 40.4 24.2 33.6 28.6 40.2 21.3 34.3 37.6 28.4 36.7 22.7 13.6 47.3 46.0 29.3 32.1 25.9 14.1 26.1 30.6 35.7 21.0 16.4 18.6 23.1 25.4 31.4 29.5 33.7 30.7 26.2 68.1 23.5 35.5 25.3 72.5 42.2 99.5 56.3 39.3 73.5 68.3 65.8 67.4 47.3 65.9 69.4 65.5 65.2 69.8 40.6 35.7 88.6 71.7 7.9 7.7 13.4 11.2 8.1 6.9 6.1 5.7 6.1 4.8 6.5 8.3 26.5 9.6 12.0 7.5 39.5 83.2 55.1 93.0 39.3 11.0 12.9 15.1 8.6 27.1 45.7 12.9 4.2 32.8 34.8 15.5 50.9 29.6 9.1 18.0 15.7 34.6 12.0 21.0 14.9 27.3 42.0 26.5 16.3 13.6 40.7 20.5 52.1 15.3 30.7 5.0 12.7 18.0 36.7 20.2 27.1 7.0 28.9 17.0 23.2 10.3 34.8 9.8 41.2 13.0 13.8 28.2 17.8 25.6 31.8 30.0 22.8 50.4 38.2 16.6 6.6 18.2 23.1 23.8 34.6 42.8 83.0 38.6 39.8 20.7 18.8 60.9 DYNC1LI1 DNCLI1 ENSG00000144635 "Dynein cytoplasmic 1 light intermediate chain 1" Q9Y6G9 3 32525974-32570858 "Predicted intracellular proteins" "Cell cycle, Cell division, Host-virus interaction, Mitosis, Transport" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 192.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035013 Approved Supported Centrosome,Cytosol NA NA 23000 "Cluster 14: Monocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 28: BEWO - Transcription regulation" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Centrosome, Cytosol" "HPA035013: AB_10600807" "unprognostic (1.23e-1)" "unprognostic (1.44e-1)" "unprognostic (1.78e-2)" "unprognostic (2.25e-2)" "unprognostic (1.55e-1)" "unprognostic (5.38e-2)" "prognostic unfavorable (9.19e-9)" "unprognostic (1.07e-1)" "unprognostic (1.30e-1)" "unprognostic (7.26e-3)" "unprognostic (5.02e-2)" "unprognostic (1.05e-2)" "unprognostic (2.21e-2)" "unprognostic (2.14e-2)" "unprognostic (5.51e-2)" "unprognostic (4.58e-2)" "unprognostic (2.27e-2)" 17.9 11.3 16.3 17.8 17.3 37.4 21.3 23.9 23.2 15.3 12.9 15.6 13.6 18.6 12.4 15.7 16.3 16.1 48.6 17.0 20.7 21.2 18.7 19.2 20.4 19.2 17.0 16.6 17.8 21.4 13.6 13.0 22.7 20.6 15.7 39.7 11.8 13.8 46.6 35.0 15.0 22.4 14.8 19.5 14.3 40.8 18.2 22.7 14.5 35.2 20.6 19.9 14.1 17.5 40.1 42.2 64.5 40.7 36.2 42.4 177.7 60.4 82.8 106.4 86.9 45.2 33.7 49.7 39.9 61.5 50.6 20.1 65.4 47.3 100.8 47.7 45.5 66.2 28.9 40.7 44.4 75.6 36.9 34.5 37.1 75.3 58.4 38.8 69.8 55.9 75.8 44.6 57.9 32.0 58.2 33.7 66.8 38.1 56.1 50.7 34.4 51.8 44.2 36.0 27.6 41.1 42.4 52.1 47.0 51.2 43.7 43.9 52.3 58.2 48.9 51.2 61.6 32.0 87.1 80.7 32.7 64.5 46.6 33.1 29.5 26.6 10.3 35.4 11.0 13.0 11.1 11.7 33.0 13.4 7.8 10.3 62.7 16.4 59.0 18.0 13.7 28.9 16.3 17.3 23.9 23.2 17.0 20.7 19.2 17.0 22.7 14.8 18.2 17.5 48.6 25.6 28.3 20.5 49.4 43.0 30.9 40.7 40.5 48.0 30.9 28.8 95.7 11.5 40.2 14.7 18.8 34.9 53.8 14.2 46.9 50.5 102.6 65.8 54.9 39.3 30.9 48.8 43.6 46.5 36.6 37.6 25.0 66.8 17.1 29.2 23.6 28.8 39.4 65.6 55.0 23.0 26.4 35.9 54.2 39.9 26.1 50.7 28.4 28.1 80.0 37.2 34.0 25.6 33.5 56.1 20.0 28.6 28.7 23.4 18.9 61.9 44.3 81.9 46.0 36.7 44.9 192.0 169.5 23.7 50.2 11.1 40.8 39.9 16.8 15.0 EBI3 "IL27B, IL35B" ENSG00000105246 "Epstein-Barr virus induced 3" Q14213 19 4229523-4237528 "Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "placenta: 147.6" "Group enriched" "Detected in some" 4 "Extravillous trophoblasts: 485.6;monocytes: 505.7;Syncytiotrophoblasts: 336.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "intermediate monocyte: 4.8;memory B-cell: 18.7;naive B-cell: 14.7;non-classical monocyte: 6.3" "Group enriched" "Detected in many" 14 "B-cells: 18.7;monocytes: 6.3" "Cell line enriched" "Detected in some" 13 "HDLM-2: 218.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA046635 Enhanced "Secreted to blood" NA NA 203000 1400000 "Cluster 19: B-cells - Humoral immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 44: HDLM-2 - Immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA046635: AB_2679729" "unprognostic (7.26e-2)" "unprognostic (1.49e-2)" "unprognostic (9.44e-2)" "unprognostic (1.31e-1)" "unprognostic (2.59e-1)" "unprognostic (2.24e-2)" "unprognostic (1.02e-1)" "unprognostic (2.10e-2)" "unprognostic (7.78e-2)" "unprognostic (4.87e-2)" "unprognostic (4.25e-3)" "unprognostic (8.27e-2)" "prognostic unfavorable (1.04e-8)" "unprognostic (1.97e-1)" "unprognostic (2.78e-2)" "unprognostic (9.29e-2)" "unprognostic (4.67e-2)" 4.7 4.7 3.8 14.6 3.3 1.2 1.7 3.4 5.3 1.5 3.2 3.0 4.3 1.1 0.1 1.0 2.4 5.4 1.4 3.8 3.7 2.1 3.3 2.9 20.2 5.7 4.2 1.3 2.5 0.4 1.7 147.6 5.2 1.8 1.6 0.1 1.8 1.4 0.2 0.6 8.4 2.1 4.5 34.0 3.7 0.9 5.8 9.4 0.9 0.4 7.3 4.8 1.0 6.1 0.1 1.7 0.1 0.0 0.0 0.0 7.3 0.7 4.2 0.4 0.2 1.3 1.2 4.2 16.4 0.0 2.0 0.1 0.0 0.0 0.0 218.8 0.0 0.0 0.1 0.2 0.3 0.0 7.7 0.4 0.0 2.1 0.6 1.6 0.1 0.0 0.4 0.5 0.1 0.1 0.0 3.0 0.4 0.0 0.0 0.0 0.6 0.3 2.6 0.0 0.2 0.4 0.0 0.0 0.0 2.7 0.2 0.2 0.9 0.3 5.1 0.0 0.2 0.4 0.0 0.2 0.3 0.0 0.6 0.0 0.1 0.0 0.0 4.8 0.0 18.7 0.0 0.0 0.8 14.7 0.0 0.0 0.2 0.0 6.3 0.0 0.0 0.6 3.8 3.3 3.4 5.3 3.8 3.7 5.7 4.2 5.2 4.5 5.8 6.1 0.5 0.0 0.5 0.3 8.4 0.4 0.0 13.3 0.0 0.0 0.2 0.6 0.1 1.5 10.7 0.0 0.0 10.6 0.5 0.0 0.0 2.8 0.0 0.3 0.4 1.3 0.0 0.0 0.6 0.9 485.6 0.7 0.0 0.3 11.4 0.0 1.1 0.1 9.6 0.0 0.4 0.0 6.1 102.6 11.3 0.0 0.0 19.0 0.0 5.6 505.7 0.1 0.0 0.0 0.1 0.6 0.0 0.0 2.6 0.1 0.0 0.6 1.5 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.1 336.4 1.0 0.1 0.0 0.1 EBP "CDPX2, CHO2, CPX, CPXD" ENSG00000147155 "EBP cholestenol delta-isomerase" Q15125 X 48521799-48528716 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Isomerase "Cataract, Disease variant, Dwarfism, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 328.5" "Cell type enhanced" "Detected in all" "Hepatocytes: 674.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003130 Approved Supported "Endoplasmic reticulum" NA Yes "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum" "HPA003130: AB_1078717" "unprognostic (1.90e-1)" "unprognostic (2.64e-2)" "unprognostic (2.80e-1)" "unprognostic (6.27e-2)" "unprognostic (3.41e-1)" "unprognostic (1.64e-1)" "unprognostic (1.13e-1)" "unprognostic (1.15e-1)" "unprognostic (1.34e-1)" "unprognostic (1.87e-1)" "unprognostic (4.72e-2)" "unprognostic (1.47e-1)" "unprognostic (5.14e-2)" "unprognostic (4.04e-2)" "unprognostic (5.39e-2)" "unprognostic (4.13e-1)" "unprognostic (1.36e-1)" 10.2 73.3 16.7 17.1 17.2 48.3 17.4 18.5 17.8 19.4 22.0 50.6 85.5 11.0 17.3 41.3 14.3 10.5 32.5 16.8 18.7 44.0 328.5 24.4 18.8 24.4 16.6 12.7 26.0 44.0 7.2 8.2 24.2 40.6 57.5 10.7 25.0 11.7 9.5 27.8 54.2 14.9 15.8 16.9 31.6 14.2 15.9 28.2 14.4 10.6 32.7 14.1 23.3 16.0 224.5 96.4 107.4 77.0 74.5 39.2 50.5 48.2 43.6 64.3 93.9 169.9 382.7 115.9 35.2 41.3 83.5 230.3 217.5 293.8 49.8 85.8 149.7 50.1 115.2 139.3 57.8 179.2 138.2 51.3 108.6 112.9 86.4 22.5 46.5 98.1 77.6 119.5 50.7 163.7 119.1 199.9 118.2 88.3 199.1 93.8 10.3 363.7 175.6 68.8 110.0 59.6 175.4 122.6 31.2 91.5 122.9 71.1 46.6 33.1 56.2 132.9 63.1 47.5 72.1 107.7 78.7 239.7 40.6 96.1 37.7 97.1 129.4 53.4 104.5 71.5 90.5 116.7 53.5 57.2 76.5 99.7 7.3 63.9 57.2 105.4 103.1 93.6 16.7 17.2 18.5 17.8 16.8 18.7 24.4 16.6 24.2 15.8 15.9 16.0 15.2 32.1 49.8 2.9 38.9 37.1 58.2 245.6 23.3 23.8 57.8 26.2 49.9 77.2 116.6 53.3 8.4 55.9 74.5 140.3 39.2 91.7 10.5 30.5 14.7 26.1 30.0 48.8 7.4 239.1 113.0 21.4 36.2 56.5 40.6 41.2 27.1 674.6 65.0 8.4 10.3 96.8 93.6 30.2 36.0 11.8 13.4 31.9 37.4 4.7 34.8 19.3 101.0 5.0 5.1 156.7 137.3 14.7 54.4 46.4 171.9 99.7 34.8 23.3 13.1 12.5 23.6 8.7 22.7 47.6 45.5 37.5 57.1 128.7 149.1 71.1 EEF1G EF1G ENSG00000254772 "Eukaryotic translation elongation factor 1 gamma" P26641 11 62559596-62574086 "Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis" "Elongation factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 1021.0;Plasma cells: 770.5;Squamous epithelial cells: 1166.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040688, HPA055316" Enhanced Approved "Golgi apparatus,Cytosol" NA NA 2500000 "Cluster 30: Non-specific - Translation" "Cluster 59: Non-specific - Translation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 59: Non-specific - Transcription" Cytosol "Golgi apparatus" "HPA040688: AB_10961632, HPA055316: AB_2732593" "unprognostic (2.12e-1)" "unprognostic (1.23e-1)" "unprognostic (2.44e-1)" "unprognostic (1.37e-2)" "unprognostic (2.28e-1)" "unprognostic (1.60e-1)" "unprognostic (9.22e-4)" "unprognostic (1.14e-1)" "unprognostic (5.14e-2)" "unprognostic (5.07e-3)" "unprognostic (1.86e-1)" "unprognostic (8.59e-2)" "unprognostic (8.99e-2)" "unprognostic (1.00e-1)" "unprognostic (1.08e-1)" "unprognostic (1.16e-1)" "unprognostic (6.04e-2)" 1237.6 883.6 646.7 951.1 663.7 1897.3 1890.9 640.9 722.0 1595.1 659.8 1229.0 1094.9 1078.6 1079.3 1634.9 1555.9 749.8 1089.3 616.4 690.9 1162.4 885.3 818.1 1532.7 678.1 661.0 2604.5 2191.5 835.7 708.1 780.5 675.9 1219.1 1272.4 416.0 1588.0 875.6 4810.2 2215.7 1098.5 991.5 690.1 1073.0 1090.2 441.9 677.4 1281.7 1050.2 3030.5 1951.7 1173.7 1440.6 676.7 1773.6 1824.3 1859.1 2656.2 2742.6 3529.1 1866.2 1505.0 2692.9 1830.1 1392.3 2045.9 2161.9 5161.2 2365.4 2392.2 1048.0 2018.3 2229.8 2200.1 1663.3 1693.2 2071.2 1348.7 2061.8 2120.7 2974.2 2810.2 1523.6 4060.8 3913.9 1812.1 4419.8 3014.9 2562.7 1777.2 2755.8 2451.2 2190.6 3611.0 3035.5 4895.3 2304.9 1546.3 1575.0 2545.1 2390.9 4978.7 2454.9 2276.4 1608.2 2002.3 901.7 3010.3 4214.5 1179.1 3496.3 3012.0 1759.8 1057.1 1476.4 2070.0 1338.6 1680.0 1783.1 2609.2 1210.8 2005.2 1517.1 883.9 2365.5 589.6 2182.3 2151.6 4333.1 5399.6 4153.2 2825.0 3623.0 5080.7 6117.7 4188.5 320.6 3285.2 1837.0 2869.7 3307.5 11090.3 646.7 663.7 640.9 722.0 616.4 690.9 678.1 661.0 675.9 690.1 677.4 676.7 2.8 150.6 366.9 14.4 403.6 7.9 2.5 8.8 1021.0 0.5 21.9 10.3 0.0 14.3 300.8 1.8 2.1 17.7 9.6 63.7 3.9 124.8 4.3 2.2 7.2 70.2 148.5 405.0 8.4 188.5 26.8 149.5 252.8 3.5 375.6 1.8 11.0 4.9 12.5 0.0 13.8 152.0 4.1 8.8 4.9 18.8 3.1 134.7 1.8 24.4 126.4 0.8 16.5 6.0 13.0 114.9 121.0 2.2 770.5 3.0 132.1 12.1 152.0 0.5 0.0 1.6 43.9 1.4 0.8 1166.7 6.1 21.1 235.3 1.1 223.8 2.3 EGLN3 "HIFPH3, PHD3" ENSG00000129521 "Egl-9 family hypoxia inducible factor 3" Q9H6Z9 14 33924227-34462774 "Enzymes, Predicted intracellular proteins" "Apoptosis, DNA damage" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 110.3;skin 1: 118.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 213.7;Cardiomyocytes: 105.8;Distal enterocytes: 135.5;Extravillous trophoblasts: 115.9;Suprabasal keratinocytes: 231.6" "Cancer enhanced" "Detected in all" "renal cancer: 50.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 10 "plasmacytoid DC: 25.5" "Lineage enriched" "Detected in many" 14 "dendritic cells: 25.5" "Cell line enhanced" "Detected in many" "RH-30: 44.6;RPTEC TERT1: 38.2;RT4: 122.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064895 Supported Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 65: Plasmacytoid DCs - Unknown function" Cytosol "HPA064895: AB_2685384" "unprognostic (3.58e-2)" "unprognostic (4.76e-3)" "unprognostic (1.75e-1)" "unprognostic (8.87e-2)" "unprognostic (6.88e-2)" "unprognostic (1.38e-2)" "prognostic unfavorable (2.14e-5)" "unprognostic (1.39e-3)" "unprognostic (3.44e-2)" "unprognostic (1.79e-1)" "unprognostic (2.93e-2)" "unprognostic (2.90e-1)" "prognostic unfavorable (2.50e-4)" "unprognostic (1.37e-1)" "unprognostic (5.21e-2)" "unprognostic (4.71e-2)" "unprognostic (6.30e-2)" 14.6 0.8 32.9 9.4 40.9 0.3 10.0 38.2 37.5 12.3 15.4 25.9 35.7 10.0 4.4 27.0 9.4 13.8 110.3 29.7 38.9 16.3 4.9 8.3 5.7 34.3 37.5 2.1 4.3 0.3 3.4 25.4 32.2 9.1 20.0 15.2 11.2 12.0 20.8 118.2 40.9 11.7 31.9 4.9 37.7 1.1 42.9 4.9 2.8 6.4 9.8 51.3 20.8 36.1 31.1 8.0 0.9 32.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 8.2 0.0 10.0 0.1 0.9 0.9 15.0 29.4 0.0 3.1 8.0 8.3 20.5 1.0 0.0 0.0 0.4 4.0 14.5 0.0 0.1 0.0 0.0 2.3 16.9 0.0 0.4 2.7 0.7 0.1 24.3 26.7 2.8 0.0 44.6 11.1 38.2 122.9 6.2 7.0 2.0 11.8 3.2 18.2 12.0 0.1 0.0 0.2 3.2 0.0 1.8 0.4 6.7 0.1 7.2 0.0 0.5 0.0 0.0 1.8 0.1 0.0 0.0 0.0 1.2 0.9 2.6 0.0 0.1 0.1 0.1 1.1 0.0 25.5 0.0 0.9 32.9 40.9 38.2 37.5 29.7 38.9 34.3 37.5 32.2 31.9 42.9 36.1 6.0 0.0 0.6 36.2 1.6 213.7 49.0 56.6 3.4 11.6 16.0 17.0 105.8 4.3 24.8 9.2 2.1 11.4 16.0 135.5 9.8 15.6 1.8 42.3 8.5 25.1 16.2 0.4 1.0 6.9 115.9 16.8 74.9 17.2 1.3 0.1 12.5 0.3 3.1 1.7 4.3 31.6 12.2 1.9 62.8 4.9 2.5 10.8 40.9 0.0 0.9 11.6 0.0 6.6 54.2 46.6 41.9 0.7 0.4 17.4 59.7 20.5 37.2 2.4 0.0 17.7 9.4 1.7 0.3 4.1 231.6 103.0 4.5 1.2 14.1 25.7 ENSA "ARPP-19e, MGC4319, MGC78563, MGC8394" ENSG00000143420 "Endosulfine alpha" O43768 1 150600851-150629612 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 11 "U-698: 8664.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051294 Uncertain Approved Nucleoplasm,Nucleoli,Microtubules,Cytosol NA NA 700000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 3: Monocytes - Immune response regulation" "Nucleoplasm, Nucleoli" "Microtubules, Cytosol" "HPA051294: AB_2681425" "unprognostic (6.27e-2)" "prognostic favorable (8.24e-4)" "unprognostic (1.06e-1)" "unprognostic (2.21e-2)" "unprognostic (2.58e-1)" "unprognostic (8.24e-2)" "unprognostic (1.94e-3)" "unprognostic (1.82e-1)" "unprognostic (2.02e-1)" "unprognostic (1.44e-3)" "unprognostic (1.21e-1)" "unprognostic (5.40e-2)" "unprognostic (2.21e-3)" "unprognostic (1.26e-1)" "unprognostic (2.75e-1)" "unprognostic (7.64e-2)" "unprognostic (8.07e-3)" 140.5 106.6 151.2 115.1 156.7 219.8 154.9 133.6 188.2 145.2 132.6 135.9 133.6 117.8 183.3 288.0 100.5 94.9 120.2 161.6 144.1 118.8 148.8 124.0 128.4 137.2 135.6 102.4 108.5 173.0 92.0 103.7 134.2 97.7 123.9 121.8 122.9 94.6 301.0 241.3 132.7 105.8 136.9 99.7 124.1 45.2 147.4 157.8 134.4 212.3 146.7 147.0 165.6 157.0 287.1 170.8 236.9 206.9 149.7 126.8 220.7 141.0 148.4 199.9 171.7 207.3 216.6 288.9 196.8 122.1 125.1 238.3 198.5 325.4 160.1 415.1 277.4 434.3 239.6 158.2 108.3 372.1 462.6 100.5 202.0 214.1 293.6 118.8 206.2 224.8 321.7 551.8 140.9 775.5 302.3 272.6 431.2 386.2 211.1 298.6 199.9 328.0 299.2 306.0 303.8 193.3 201.6 385.6 222.1 200.8 533.9 442.9 208.2 143.9 261.9 171.8 340.3 309.4 441.4 8664.2 197.1 357.6 191.8 67.3 54.4 94.3 55.6 62.9 52.2 64.3 46.3 57.5 70.7 55.3 37.7 56.0 53.0 68.8 64.3 58.3 58.2 75.1 151.2 156.7 133.6 188.2 161.6 144.1 137.2 135.6 134.2 136.9 147.4 157.0 103.1 41.7 166.1 20.9 132.9 190.3 225.1 303.9 124.7 59.7 152.7 117.1 102.6 98.7 172.9 82.8 45.9 286.5 148.9 170.7 254.3 160.3 9.7 109.1 68.5 114.2 130.8 178.2 44.7 152.4 184.2 85.9 71.9 93.7 224.3 51.1 80.3 86.9 203.3 67.3 29.3 169.1 211.6 101.1 171.4 17.7 86.0 123.3 103.2 19.7 409.7 83.6 184.4 21.6 19.3 91.5 146.8 104.2 135.6 128.0 187.2 186.0 128.8 50.0 72.3 85.5 94.4 27.6 25.0 269.7 286.8 382.8 140.4 87.9 163.9 253.7 EPCAM "17-1A, 323/A3, CD326, CO-17A, EGP-2, EGP34, EGP40, Ep-CAM, ESA, GA733-2, HEA125, KS1/4, KSA, Ly74, M4S1, MH99, MIC18, MK-1, MOC31, TACST-1, TACSTD1, TROP1" ENSG00000119888 "Epithelial cell adhesion molecule" P16422 2 47345158-47387601 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Tumor antigen" "Cancer-related genes, Disease variant, FDA approved drug targets, Hereditary nonpolyposis colorectal cancer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 806.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 2317.0;Ductal cells: 999.6;Intestinal goblet cells: 1378.2;Paneth cells: 2437.0;Proximal enterocytes: 2681.1;Undifferentiated cells: 1607.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 538.9;CACO-2: 680.9;CAPAN-2: 944.4;OE19: 911.8;RPTEC TERT1: 398.6" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "CAB003809, HPA026761, CAB030012, CAB055098, HPA067463" Enhanced Supported "Plasma membrane" NA NA 22000 "Cluster 9: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "CAB003809: AB_562285, CAB030012: AB_756075, CAB055098: AB_2335685, HPA026761: AB_1848198, HPA067463: AB_2685846" "unprognostic (6.79e-2)" "unprognostic (2.28e-1)" "unprognostic (1.59e-2)" "unprognostic (1.16e-2)" "unprognostic (1.61e-1)" "unprognostic (3.49e-2)" "unprognostic (2.01e-1)" "unprognostic (3.61e-2)" "unprognostic (3.40e-1)" "prognostic favorable (3.30e-4)" "unprognostic (5.27e-2)" "unprognostic (3.28e-2)" "prognostic favorable (1.04e-6)" "unprognostic (6.38e-3)" "unprognostic (1.28e-1)" "unprognostic (6.45e-3)" "unprognostic (6.08e-2)" 4.4 12.2 3.1 77.0 4.0 10.2 99.7 1.5 3.1 116.2 1.0 806.0 726.5 33.0 238.9 10.8 114.3 71.1 0.6 3.3 9.2 223.1 3.1 74.7 0.9 2.8 3.2 1.2 125.4 219.5 86.9 1.7 3.4 60.5 751.0 0.6 119.8 52.8 0.1 8.8 769.6 22.2 2.6 1.4 172.4 21.7 10.4 6.4 286.8 0.1 2.8 30.9 4.2 2.6 538.9 5.4 0.4 1.2 0.0 0.0 321.3 0.2 0.0 0.6 0.0 680.9 944.4 0.1 141.5 1.0 0.4 247.3 4.6 62.2 2.0 0.1 56.3 0.3 2.5 261.6 0.1 0.3 0.4 0.0 17.6 0.0 0.0 0.0 0.8 0.0 160.9 0.0 0.3 269.7 0.5 24.0 164.3 911.8 31.4 0.3 0.0 136.9 398.6 231.3 354.0 3.2 4.3 187.7 0.6 132.7 158.3 1.0 0.7 0.3 6.3 2.0 1.1 39.2 0.6 0.8 0.5 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 3.1 4.0 1.5 3.1 3.3 9.2 2.8 3.2 3.4 2.6 10.4 2.6 3.7 310.9 148.1 1.3 7.0 9.3 227.6 127.4 14.2 0.5 184.7 112.9 2.0 243.1 222.8 448.8 0.0 16.4 2.3 2317.0 76.3 999.6 8.6 434.7 35.3 5.8 498.1 23.1 1.1 402.8 6.5 6.3 150.3 445.3 32.5 11.8 1.4 0.6 2.9 0.0 0.4 1378.2 486.2 0.0 5.2 5.6 20.5 5.6 35.6 0.0 11.5 15.7 0.0 0.5 1.2 617.5 2437.0 18.8 1.8 257.9 2681.1 195.9 219.0 0.7 13.1 0.5 13.7 83.5 130.3 33.3 10.4 6.0 9.4 70.3 1607.7 230.7 EPHX2 ABHD20 ENSG00000120915 "Epoxide hydrolase 2" P34913 8 27490781-27545564 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Aromatic hydrocarbons catabolism, Detoxification, Lipid metabolism" "Hydrolase, Multifunctional enzyme" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 333.2" "Cell type enhanced" "Detected in many" "Distal tubular cells: 180.0;Hepatocytes: 131.5;Proximal enterocytes: 399.0;Proximal tubular cells: 259.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory CD4 T-cell: 35.0;naive CD4 T-cell: 106.7;naive CD8 T-cell: 50.4;T-reg: 29.6" "Lineage enriched" "Detected in many" 23 "T-cells: 106.7" "Cell line enhanced" "Detected in many" "JURKAT: 139.4;K-562: 51.6;OE19: 102.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023094, HPA023660" Enhanced Enhanced Cytosol NA NA 1100000 "Cluster 32: T-cells - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA023094: AB_1848214, HPA023660: AB_1848215" "unprognostic (1.30e-1)" "prognostic favorable (2.45e-4)" "unprognostic (2.99e-2)" "unprognostic (3.62e-2)" "unprognostic (1.76e-2)" "unprognostic (3.30e-3)" "unprognostic (1.26e-3)" "unprognostic (3.31e-3)" "unprognostic (1.46e-1)" "unprognostic (3.55e-2)" "unprognostic (4.14e-3)" "unprognostic (1.98e-1)" "prognostic favorable (1.98e-10)" "unprognostic (9.82e-2)" "unprognostic (1.73e-1)" "unprognostic (8.12e-2)" "unprognostic (2.26e-1)" 19.3 74.0 14.5 9.1 15.0 1.9 30.1 14.4 14.1 21.0 42.2 61.4 112.8 17.7 27.2 38.6 41.6 9.4 29.1 13.2 15.3 166.3 333.2 11.2 17.2 16.1 17.3 38.0 64.5 54.8 35.8 8.5 15.9 64.6 57.6 21.5 36.5 27.2 16.2 43.4 128.4 15.4 15.8 10.8 23.4 9.0 15.8 65.9 22.6 13.8 20.8 19.7 23.4 15.7 15.3 10.1 6.3 8.1 0.4 0.0 4.8 1.3 0.9 0.7 0.2 8.0 10.1 0.1 5.9 4.1 3.2 10.7 1.1 2.6 0.5 0.0 4.7 22.5 1.1 24.8 3.4 0.1 4.5 8.6 10.7 0.1 1.1 2.5 0.5 139.4 51.6 0.2 0.0 4.7 14.9 0.5 10.1 102.4 17.2 0.1 0.1 0.4 8.7 2.2 5.1 16.0 12.1 14.2 15.0 4.6 21.8 4.2 0.2 0.0 3.8 1.8 0.1 12.5 10.1 0.2 0.4 0.1 0.1 0.1 0.1 0.0 7.8 0.0 11.3 4.5 35.0 12.7 0.1 2.5 106.7 50.4 0.2 4.6 0.1 0.2 29.6 20.0 14.5 15.0 14.4 14.1 13.2 15.3 16.1 17.3 15.9 15.8 15.8 15.7 6.3 6.4 17.0 16.3 6.1 11.9 18.6 10.1 29.6 34.1 17.2 18.4 23.7 20.0 9.7 27.6 79.2 22.8 1.0 82.7 180.0 8.8 7.5 6.9 4.8 9.4 23.4 3.8 3.0 6.4 2.5 12.1 15.8 1.5 5.7 17.4 17.5 131.5 2.2 33.7 7.2 63.4 2.0 4.6 1.2 4.8 29.8 3.6 5.4 2.8 2.6 91.5 3.1 7.5 5.1 3.1 83.7 18.8 4.5 20.5 399.0 259.3 24.1 52.4 0.0 11.5 10.2 1.3 13.9 39.2 18.3 8.2 11.9 78.5 101.3 10.8 EPHX4 "ABHD7, EH4, EPHXRP, FLJ90341" ENSG00000172031 "Epoxide hydrolase 4" Q8IUS5 1 92029985-92063538 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 10.9;choroid plexus: 5.7" "Group enriched" "Detected in many" 5 "Excitatory neurons: 55.3;Inhibitory neurons: 32.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 12.1" "Lineage enriched" "Detected in single" 21 "T-cells: 12.1" "Cell line enhanced" "Detected in some" "A-431: 15.4;CAPAN-2: 13.0;EFO-21: 25.9;RPTEC TERT1: 36.1;U-251 MG: 10.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA035067 Uncertain Approved Vesicles NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 65: Brain - Ion transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA035067: AB_10601465" "unprognostic (1.27e-1)" "unprognostic (4.17e-2)" "unprognostic (6.76e-3)" "unprognostic (6.10e-8)" "prognostic unfavorable (9.43e-4)" "unprognostic (5.36e-3)" "unprognostic (2.72e-4)" "unprognostic (4.85e-2)" "unprognostic (9.44e-3)" "unprognostic (7.93e-2)" "prognostic unfavorable (2.00e-4)" "unprognostic (2.53e-1)" "unprognostic (6.36e-6)" "unprognostic (6.93e-3)" "unprognostic (1.02e-1)" "unprognostic (1.67e-1)" "unprognostic (1.25e-1)" 0.5 0.5 4.0 0.5 9.2 0.0 1.4 1.9 10.9 0.9 5.7 0.6 0.6 0.6 0.5 0.8 0.4 0.4 0.5 6.9 2.3 0.4 0.0 0.6 0.2 3.1 2.3 0.1 0.0 0.4 1.1 0.8 3.1 0.9 0.5 2.1 0.2 1.8 0.1 0.5 0.4 1.1 1.8 0.0 0.3 1.2 2.8 0.0 1.8 0.1 0.2 0.7 0.2 5.5 15.4 0.5 2.9 0.0 0.0 0.0 0.7 0.3 5.5 0.5 0.3 0.0 13.0 0.0 25.9 0.0 3.9 0.2 0.5 1.2 0.5 0.0 8.0 0.0 0.1 0.0 0.2 1.1 0.0 0.9 0.7 0.0 0.0 9.4 4.5 0.0 0.1 0.0 0.4 0.9 2.2 0.6 2.8 0.0 5.2 0.5 0.3 0.0 36.1 3.0 1.8 2.2 9.1 0.0 2.9 0.2 0.0 2.2 0.2 0.0 0.1 0.0 10.9 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 12.1 0.0 2.0 0.1 1.4 3.0 0.0 0.0 0.3 2.8 0.0 0.5 0.0 0.0 0.0 1.5 4.0 9.2 1.9 10.9 6.9 2.3 3.1 2.3 3.1 1.8 2.8 5.5 2.0 0.0 0.0 4.9 0.0 0.1 0.1 2.0 0.0 2.0 6.7 4.6 1.0 0.0 1.5 0.0 2.1 0.4 3.2 0.1 0.0 0.4 1.7 1.0 0.1 6.2 0.0 0.0 55.3 0.9 0.7 0.3 0.0 1.3 0.0 0.3 0.4 0.0 0.2 1.7 32.5 0.0 0.0 0.0 0.4 0.1 0.0 0.2 3.6 4.7 0.1 8.6 0.0 5.5 2.7 5.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 1.6 0.0 0.1 0.8 6.0 0.7 0.1 0.4 0.0 1.1 0.2 0.3 0.3 EPN3 "FLJ20778, MGC129899" ENSG00000049283 "Epsin 3" Q9H201 17 50532682-50543750 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 35.9;stomach 1: 37.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 77.9;Distal enterocytes: 27.6;Gastric mucus-secreting cells: 44.9;Intestinal goblet cells: 24.9;Squamous epithelial cells: 30.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 28.6;HBEC3-KT: 40.3;MCF7: 66.4;OE19: 62.8;RT4: 50.2;SK-BR-3: 25.8;T-47d: 57.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA055546, HPA063224" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 6: T47d - Mammary gland" "Cluster 47: Cytotrophoblasts - Unknown function" Vesicles Nucleoplasm "HPA055546: AB_2682844, HPA063224: AB_2684964" "unprognostic (1.91e-2)" "unprognostic (1.99e-2)" "unprognostic (2.41e-1)" "unprognostic (2.91e-2)" "unprognostic (1.25e-3)" "unprognostic (2.06e-1)" "unprognostic (5.70e-3)" "unprognostic (7.62e-2)" "unprognostic (1.43e-1)" "unprognostic (1.20e-1)" "unprognostic (6.66e-3)" "unprognostic (1.00e-2)" "prognostic favorable (1.53e-5)" "unprognostic (1.45e-1)" "unprognostic (1.16e-1)" "unprognostic (4.90e-1)" "unprognostic (3.52e-3)" 0.2 8.9 2.3 0.8 1.3 0.6 2.3 6.4 6.0 6.5 1.2 7.1 6.8 0.4 3.2 35.9 7.5 5.9 7.1 0.7 2.1 6.0 0.1 0.3 0.0 11.5 5.4 13.5 23.0 21.2 0.8 4.2 13.6 9.9 4.4 0.2 11.1 5.6 0.1 30.5 3.2 0.1 0.5 0.0 37.3 2.8 13.4 3.2 1.1 0.0 3.7 5.5 12.9 1.8 20.5 0.3 0.0 0.2 0.0 0.0 5.3 0.0 0.0 0.0 0.0 14.7 12.1 0.0 0.2 0.0 0.1 28.6 0.0 40.3 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.1 0.2 0.1 21.8 0.1 3.0 0.0 0.0 0.1 0.0 0.0 0.0 66.4 0.3 0.0 0.0 62.8 0.4 0.0 0.0 0.1 0.2 50.2 0.4 0.0 0.0 25.8 0.0 0.4 57.4 0.2 1.5 0.3 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 1.3 6.4 6.0 0.7 2.1 11.5 5.4 13.6 0.5 13.4 1.8 0.2 0.0 0.0 0.0 0.4 2.3 4.4 4.1 10.8 2.9 6.5 3.4 5.4 8.6 8.3 18.4 0.0 77.9 0.0 27.6 5.9 9.2 1.0 3.8 0.6 0.4 3.6 0.0 1.0 11.5 7.4 0.8 44.9 5.5 0.0 3.1 0.0 0.0 5.9 0.0 1.7 24.9 2.0 0.0 0.0 2.1 2.8 0.5 0.0 1.0 0.6 0.6 0.0 0.0 0.0 3.4 10.3 0.0 1.3 4.9 2.1 0.3 4.3 0.9 0.0 0.0 0.8 0.0 0.5 30.0 5.5 10.7 0.2 12.4 19.3 7.8 EPOR ENSG00000187266 "Erythropoietin receptor" P19235 19 11377207-11384342 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" Receptor "Cancer-related genes, Congenital erythrocytosis, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 114.7;Hepatic stellate cells: 66.8;Hofbauer cells: 42.4" "Cancer enhanced" "Detected in all" "thyroid cancer: 20.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA077654 Supported "Nuclear speckles,Plasma membrane" "Intracellular and membrane" NA Yes "Cluster 14: Monocytes - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 6: Erythroid cells - Oxygen transport" "Plasma membrane" "Nuclear speckles" "HPA077654: " "unprognostic (9.13e-2)" "unprognostic (7.14e-2)" "unprognostic (1.45e-2)" "unprognostic (1.04e-1)" "unprognostic (1.88e-1)" "unprognostic (1.11e-1)" "unprognostic (3.70e-1)" "unprognostic (1.50e-2)" "unprognostic (5.60e-2)" "unprognostic (9.00e-2)" "prognostic favorable (3.17e-5)" "unprognostic (6.37e-3)" "unprognostic (1.59e-2)" "unprognostic (2.08e-1)" "unprognostic (2.00e-1)" "unprognostic (7.48e-2)" "unprognostic (1.01e-3)" 6.5 17.5 6.0 1.4 6.3 22.4 5.0 6.7 8.2 7.1 7.7 2.7 1.4 3.3 13.6 1.3 6.7 2.3 9.7 6.3 6.0 21.6 10.7 6.4 2.2 6.1 6.1 3.1 11.8 23.2 8.2 8.0 6.4 4.6 1.7 3.3 3.3 7.3 2.3 1.6 2.3 1.8 6.0 11.9 7.8 1.8 6.2 1.7 30.2 1.5 1.6 3.1 3.7 6.3 3.7 1.2 3.6 4.2 5.3 3.4 2.1 2.2 7.0 3.6 4.5 1.3 1.4 2.5 4.0 4.1 5.0 0.9 2.8 1.4 4.1 2.1 1.6 14.3 1.3 2.1 3.8 2.9 5.5 2.4 0.5 4.8 3.3 8.5 8.5 5.3 12.5 12.0 4.1 3.3 2.7 3.5 1.9 2.0 9.6 7.2 6.3 5.6 3.4 1.9 1.4 11.0 1.5 2.0 6.4 3.7 3.6 4.9 3.5 1.9 2.6 6.6 2.1 6.0 4.7 2.8 10.5 2.9 2.1 9.3 3.7 3.0 1.7 4.6 3.6 2.0 3.4 2.5 2.1 1.2 3.7 2.2 10.2 0.8 7.3 0.1 3.3 2.4 6.0 6.3 6.7 8.2 6.3 6.0 6.1 6.1 6.4 6.0 6.2 6.3 6.1 19.2 18.8 24.8 11.5 2.3 4.0 2.0 2.8 3.8 3.6 6.1 6.5 5.7 3.1 20.2 0.0 2.2 5.2 1.3 3.9 2.2 0.8 9.9 6.8 13.5 8.4 114.7 2.2 3.3 12.2 9.8 15.3 13.9 26.6 1.2 66.8 3.5 42.4 1.7 3.0 3.5 2.0 17.0 4.0 0.6 2.8 15.4 8.8 7.5 4.6 7.9 11.3 1.0 1.6 3.1 0.4 4.1 3.8 1.8 0.2 1.0 2.9 2.5 19.7 3.8 18.5 5.1 7.7 1.6 1.0 3.0 9.6 2.6 1.8 1.2 EPS15L1 eps15R ENSG00000127527 "Epidermal growth factor receptor pathway substrate 15 like 1" Q9UBC2 19 16355239-16472085 "Plasma proteins, Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019237, HPA055309" Approved Approved Vesicles NA NA 110000 "Cluster 10: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 29: Early spermatids - Spermatogenesis" Vesicles "HPA019237: AB_1848223, HPA055309: AB_2682780" "unprognostic (3.06e-2)" "unprognostic (3.33e-3)" "unprognostic (2.19e-1)" "unprognostic (6.45e-3)" "unprognostic (1.35e-1)" "unprognostic (8.64e-2)" "unprognostic (2.58e-3)" "unprognostic (5.12e-2)" "unprognostic (1.07e-3)" "unprognostic (7.54e-2)" "unprognostic (5.21e-2)" "unprognostic (1.81e-2)" "prognostic favorable (8.10e-5)" "unprognostic (2.47e-1)" "unprognostic (9.59e-2)" "unprognostic (2.14e-1)" "unprognostic (3.32e-1)" 15.3 17.6 33.4 11.8 32.4 23.6 14.2 39.6 40.5 22.4 21.5 17.0 8.3 18.1 5.9 25.2 18.7 9.6 42.4 35.6 29.1 20.5 17.9 14.6 13.9 29.3 33.4 19.1 15.5 18.2 22.6 13.9 30.8 19.5 9.2 14.0 14.9 12.9 67.6 23.3 14.3 14.1 23.5 19.8 16.8 22.9 41.0 11.8 17.5 25.7 13.0 17.6 19.7 27.6 27.3 12.8 25.8 20.4 27.4 21.1 40.3 17.8 14.9 28.8 25.1 15.3 18.2 29.2 30.4 26.1 22.8 26.6 36.3 20.8 25.1 15.8 36.8 24.7 17.4 29.8 27.7 22.8 26.7 17.6 21.1 31.9 22.3 28.6 23.6 24.5 20.1 31.2 24.5 53.9 25.4 32.5 17.7 36.4 41.7 32.2 12.5 24.3 19.8 27.9 23.3 15.3 18.6 17.5 17.7 19.2 58.3 21.3 24.5 18.2 12.2 57.3 31.4 8.8 19.4 27.7 20.2 31.9 24.5 53.5 11.9 35.9 11.1 12.0 10.5 20.8 9.8 12.0 9.2 19.3 10.1 7.8 56.2 19.1 14.4 8.6 10.7 9.0 33.4 32.4 39.6 40.5 35.6 29.1 29.3 33.4 30.8 23.5 41.0 27.6 10.8 9.6 9.8 62.3 22.1 16.6 14.0 12.0 12.0 30.7 9.5 8.1 20.4 7.2 10.9 9.2 50.1 21.7 30.8 11.7 9.8 11.0 74.9 10.7 13.0 11.8 11.3 13.9 49.7 5.7 19.7 16.0 16.3 12.1 12.0 22.3 11.0 8.2 20.0 11.8 63.4 10.7 24.4 10.6 14.8 15.1 18.6 13.8 3.6 30.9 13.0 9.9 34.0 36.2 35.6 9.3 9.1 20.3 18.7 15.0 9.0 12.9 14.7 25.9 19.7 20.3 13.9 18.5 16.7 22.3 24.4 10.9 15.8 18.7 9.8 22.2 EPS8L1 "DRC3, FLJ20258, MGC23164, MGC4642" ENSG00000131037 "EPS8 like 1" Q8TE68 19 55072020-55087923 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 124.3;skin 1: 59.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 104.1;Gastric mucus-secreting cells: 108.1;Paneth cells: 110.2;Syncytiotrophoblasts: 428.0;Urothelial cells: 189.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "eosinophil: 2.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 17.6;BEWO: 58.8;SK-BR-3: 19.6;T-47d: 28.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041851, HPA043545" Uncertain Supported Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 28: BEWO - Transcription regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "HPA041851: AB_2677706, HPA043545: AB_2678544" "unprognostic (1.91e-1)" "unprognostic (2.06e-1)" "prognostic unfavorable (4.44e-4)" "unprognostic (7.18e-2)" "unprognostic (9.33e-2)" "unprognostic (2.54e-2)" "unprognostic (4.61e-2)" "unprognostic (1.43e-1)" "unprognostic (1.62e-1)" "unprognostic (9.43e-2)" "unprognostic (5.84e-3)" "unprognostic (2.65e-2)" "unprognostic (3.85e-3)" "unprognostic (5.04e-3)" "unprognostic (3.02e-1)" "unprognostic (5.41e-3)" "unprognostic (2.63e-1)" 4.5 0.2 0.0 0.9 0.1 0.1 4.0 0.0 0.1 24.0 0.0 3.5 2.3 1.5 0.0 124.3 14.8 0.9 0.6 0.1 0.0 25.1 0.7 3.9 0.0 0.1 0.1 0.5 5.6 2.1 2.1 5.4 0.1 9.2 0.6 0.0 20.4 2.5 0.5 59.7 2.0 0.0 0.0 0.6 27.0 0.6 0.2 0.1 17.4 0.0 1.6 2.7 37.1 0.2 17.6 0.7 0.6 0.4 0.0 0.0 58.8 1.5 0.1 0.0 0.1 7.6 13.7 0.3 3.4 0.0 0.1 9.7 0.4 2.1 0.0 0.3 1.6 1.3 0.6 0.5 0.2 2.6 10.8 0.0 3.6 0.0 0.0 0.0 0.0 1.2 6.2 0.1 0.0 8.0 0.9 2.6 0.8 12.7 0.0 0.1 0.0 5.4 2.7 3.6 0.2 3.8 1.0 19.6 0.8 0.6 28.9 3.2 1.3 0.0 0.7 0.0 0.0 2.4 3.1 1.6 3.3 0.9 2.0 1.1 0.2 2.3 0.3 0.0 0.3 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.8 0.0 1.4 0.3 0.2 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.2 0.2 4.0 9.6 6.1 0.3 0.8 2.0 28.4 39.5 8.6 0.0 16.3 15.1 2.6 8.6 92.2 31.3 0.0 55.1 4.0 104.1 13.7 20.4 1.6 29.1 6.3 10.7 3.0 0.0 0.1 10.2 26.8 4.7 108.1 41.7 10.2 5.4 10.0 0.1 8.9 0.0 0.1 39.0 24.4 1.9 3.4 4.5 1.2 2.6 21.4 0.0 5.2 0.2 6.2 0.0 0.1 94.5 110.2 0.7 1.0 48.7 12.7 1.1 53.6 0.6 26.3 0.5 21.6 1.6 3.6 6.6 4.0 428.0 2.8 0.3 22.1 189.4 ERG28 "C14orf1, NET51" ENSG00000133935 "Ergosterol biosynthesis 28 homolog" Q9UKR5 14 75649791-75660876 "Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 152.0;Ductal cells: 95.4;Exocrine glandular cells: 110.3;Extravillous trophoblasts: 154.2;Syncytiotrophoblasts: 116.3;Theca cells: 121.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043172 Approved NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 68: Epididymis - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 7: Non-specific - Mitochondria" "HPA043172: AB_10793942" "unprognostic (2.68e-3)" "unprognostic (2.11e-2)" "unprognostic (4.55e-1)" "unprognostic (2.05e-1)" "unprognostic (1.75e-1)" "unprognostic (1.34e-3)" "unprognostic (6.25e-2)" "unprognostic (7.66e-2)" "unprognostic (4.64e-1)" "unprognostic (2.66e-2)" "unprognostic (2.47e-1)" "unprognostic (3.01e-2)" "prognostic favorable (4.30e-5)" "unprognostic (1.28e-1)" "unprognostic (2.77e-1)" "unprognostic (9.58e-3)" "unprognostic (2.20e-1)" 9.8 27.7 24.0 9.1 23.3 13.2 17.3 24.6 26.2 16.9 25.1 16.5 21.6 14.9 40.6 34.6 16.9 11.9 13.6 24.6 25.0 18.5 70.2 22.6 11.5 26.2 25.2 20.0 16.1 29.7 17.4 14.9 25.4 21.2 15.5 19.4 19.9 13.8 10.3 24.8 14.5 14.6 25.4 8.3 13.6 47.1 25.8 10.2 21.5 11.3 14.6 12.5 20.1 27.5 39.2 21.6 42.7 33.5 28.6 53.1 26.6 15.6 48.2 29.9 51.0 33.8 91.4 16.6 22.3 19.6 59.7 42.4 38.5 67.0 34.0 31.2 25.4 17.8 20.5 48.4 41.4 19.7 25.5 66.5 56.7 42.9 23.8 24.0 35.3 44.7 16.0 39.3 20.9 77.7 30.2 21.8 41.8 62.5 34.7 23.9 28.7 33.0 99.8 50.5 36.6 20.1 39.2 33.5 24.1 37.8 56.1 28.3 25.1 16.1 32.0 15.8 15.8 25.3 32.5 36.1 25.7 28.5 27.7 33.5 12.3 20.0 40.0 12.7 39.5 39.4 43.1 41.8 29.8 34.5 39.1 38.5 6.6 31.8 13.2 38.4 42.7 31.9 24.0 23.3 24.6 26.2 24.6 25.0 26.2 25.2 25.4 25.4 25.8 27.5 18.8 22.4 57.5 0.0 9.3 0.0 0.0 0.0 0.0 0.0 74.7 57.7 0.0 0.0 11.2 60.7 0.0 152.0 23.6 0.0 49.0 95.4 0.0 43.4 11.5 18.0 0.0 0.0 0.0 110.3 154.2 21.4 0.0 30.3 5.1 63.2 0.0 0.0 64.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.4 0.0 0.0 37.7 0.0 0.0 0.0 0.0 76.9 0.0 0.0 3.5 0.0 0.0 47.1 18.2 0.0 0.0 0.0 14.4 0.0 0.0 0.0 0.0 116.3 12.4 121.2 0.0 0.0 ERN2 IRE1b ENSG00000134398 "Endoplasmic reticulum to nucleus signaling 2" Q76MJ5 16 23690310-23713226 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Transcription, Transcription regulation" "Hydrolase, Kinase, Multifunctional enzyme, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "cervix: 19.5;gallbladder: 17.0;intestine: 28.9;salivary gland: 22.9;stomach 1: 51.9" "Cell type enhanced" "Detected in some" "Club cells: 38.4;Distal enterocytes: 80.2;Gastric mucus-secreting cells: 193.7;Intestinal goblet cells: 143.9;Paneth cells: 37.2;Undifferentiated cells: 70.9" "Cancer enhanced" "Detected in many" "colorectal cancer: 17.0;pancreatic cancer: 19.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "OE19: 43.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA076875 Approved Approved "Endoplasmic reticulum,Cytosol" "Intracellular and membrane" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" "Endoplasmic reticulum, Cytosol" "HPA076875: " "unprognostic (1.06e-1)" "unprognostic (5.20e-2)" "unprognostic (3.45e-1)" "unprognostic (2.98e-2)" "unprognostic (3.83e-2)" "unprognostic (1.13e-2)" "unprognostic (7.67e-4)" "unprognostic (1.31e-1)" "unprognostic (1.16e-1)" "unprognostic (4.93e-2)" "unprognostic (7.34e-2)" "unprognostic (1.19e-1)" "unprognostic (1.14e-9)" "unprognostic (1.48e-1)" "unprognostic (2.14e-1)" "unprognostic (1.06e-1)" "unprognostic (3.13e-3)" 0.1 0.4 0.1 3.0 0.1 0.0 0.1 0.6 0.4 19.5 0.2 28.9 12.9 0.0 0.0 0.9 0.4 17.0 0.0 0.1 0.2 0.1 0.0 0.8 0.0 0.2 0.1 0.0 0.9 0.0 0.2 0.0 0.2 3.5 23.0 0.0 22.9 0.1 0.0 0.2 12.4 0.9 0.0 0.0 51.9 0.1 0.1 0.0 0.0 0.0 0.0 4.6 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 43.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.2 0.0 0.1 0.0 0.0 0.1 0.1 0.6 0.4 0.1 0.2 0.2 0.1 0.2 0.0 0.1 0.4 0.0 0.0 1.1 0.0 0.8 0.0 1.5 6.8 0.0 0.0 0.0 0.0 0.5 20.0 38.4 0.0 0.0 0.5 0.0 80.2 0.0 2.3 0.1 0.5 0.2 0.1 10.8 0.0 0.2 1.9 0.0 0.1 193.7 1.6 4.5 0.1 0.0 0.0 0.1 0.0 0.1 143.9 6.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.1 33.1 37.2 0.0 0.5 1.3 6.1 0.1 16.9 0.0 0.0 1.7 1.6 0.0 0.2 0.0 0.0 0.1 0.4 0.0 70.9 11.1 ERP29 "C12orf8, ERp28, ERp31, PDI-DB, PDIA9" ENSG00000089248 "Endoplasmic reticulum protein 29" P30040 12 112013348-112023449 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039363, HPA039456" Enhanced Uncertain Nucleoplasm,Microtubules "Intracellular and membrane" NA NA 900000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" Microtubules Nucleoplasm "HPA039363: AB_10673422, HPA039456: AB_10672963" "unprognostic (2.70e-2)" "unprognostic (1.16e-1)" "unprognostic (1.96e-1)" "prognostic favorable (7.43e-5)" "unprognostic (1.13e-2)" "unprognostic (3.88e-1)" "prognostic unfavorable (2.02e-4)" "unprognostic (1.04e-2)" "unprognostic (2.00e-1)" "unprognostic (1.21e-1)" "unprognostic (5.10e-3)" "unprognostic (2.58e-1)" "unprognostic (3.21e-1)" "unprognostic (2.74e-3)" "unprognostic (3.34e-1)" "unprognostic (1.76e-1)" "unprognostic (6.26e-2)" 62.7 100.9 56.9 77.9 58.0 202.3 84.0 65.1 62.0 78.4 91.1 94.5 100.7 60.5 109.8 91.5 74.8 64.1 59.0 56.0 68.7 93.0 179.9 78.8 123.8 61.1 62.6 78.9 174.6 123.6 99.1 73.0 64.2 93.4 91.3 68.3 122.7 87.4 34.3 113.3 96.1 47.1 57.8 118.3 131.4 57.6 60.8 107.6 90.4 34.3 111.2 75.9 71.0 61.6 145.4 137.2 98.8 194.2 367.4 143.7 211.3 139.2 163.7 108.5 139.3 215.2 164.4 152.7 106.4 244.5 117.8 175.4 187.8 181.2 89.3 133.7 104.2 174.3 150.1 239.2 246.8 432.1 164.0 207.5 227.6 178.4 201.6 287.4 156.1 157.9 203.2 277.3 84.7 166.6 140.9 765.7 161.5 513.1 102.5 114.2 120.9 501.2 229.8 213.5 88.6 119.8 173.6 140.1 426.1 187.4 177.1 575.7 116.5 92.6 142.7 88.8 103.3 303.4 379.8 128.0 157.8 268.5 73.2 96.2 241.4 346.2 131.6 178.8 140.4 259.1 170.7 164.1 229.7 264.1 186.5 154.9 47.5 86.5 170.9 455.8 179.6 307.4 56.9 58.0 65.1 62.0 56.0 68.7 61.1 62.6 64.2 57.8 60.8 61.6 102.6 83.3 183.4 13.7 324.8 141.4 205.5 249.3 132.6 125.3 207.8 199.9 91.6 198.8 178.0 185.8 110.5 497.7 396.6 210.1 93.9 239.5 7.7 142.1 84.9 114.9 197.9 134.4 14.4 211.8 405.3 118.3 131.5 149.9 88.8 164.4 146.3 346.6 373.1 80.8 20.6 280.6 343.8 306.9 192.6 16.6 128.9 230.4 168.9 12.2 269.0 152.8 160.6 11.6 22.8 128.7 288.0 106.8 350.1 195.4 355.5 274.6 187.0 164.9 52.6 79.2 112.2 100.3 195.3 143.1 161.0 441.6 221.7 252.4 285.2 219.8 ERV3-1 "envR, ERV-R, ERV3, H-PLK, HERV-R" ENSG00000213462 "Endogenous retrovirus group 3 member 1, envelope" Q14264 7 64990356-65006743 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 7.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AN3-CA: 27.7" "HPA017209, HPA046508" Enhanced Approved Vesicles NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 68: Epididymis - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 52: Non-specific - Transcription" Vesicles "HPA017209: AB_2732419, HPA046508: AB_2732525" "unprognostic (2.74e-2)" "unprognostic (1.84e-1)" "unprognostic (2.11e-1)" "unprognostic (1.27e-2)" "unprognostic (4.48e-1)" "unprognostic (2.03e-1)" "unprognostic (7.00e-2)" "unprognostic (1.79e-1)" "unprognostic (4.05e-3)" "unprognostic (3.55e-1)" "unprognostic (1.57e-2)" "unprognostic (4.45e-2)" "unprognostic (4.27e-3)" "unprognostic (2.11e-1)" "unprognostic (2.19e-1)" "unprognostic (9.39e-2)" "unprognostic (1.88e-2)" 22.8 33.0 4.8 8.5 4.5 9.3 15.0 4.1 6.4 10.0 5.1 5.7 3.5 10.0 32.5 15.2 8.0 16.4 6.2 4.7 6.2 4.8 3.2 9.7 5.7 6.2 7.9 7.3 5.3 15.3 8.2 13.4 5.4 7.3 5.7 13.5 12.1 7.5 3.6 12.3 4.5 7.6 4.8 6.9 6.3 8.7 5.9 6.6 7.6 1.8 7.4 6.2 11.5 5.1 3.3 1.0 17.4 27.7 11.3 4.7 12.4 5.7 6.3 2.0 4.6 1.2 20.5 5.5 5.3 2.2 4.0 3.9 2.6 1.5 3.2 4.1 1.5 2.8 1.6 11.5 1.0 6.7 3.7 5.1 1.6 1.8 0.6 10.4 11.6 6.0 12.7 10.3 8.1 8.1 4.9 5.0 5.1 10.8 1.2 11.4 0.7 3.7 3.5 6.8 3.6 16.8 6.2 1.9 0.7 18.9 4.7 16.4 9.2 6.7 1.0 5.1 2.8 3.2 7.8 1.6 5.7 20.8 4.1 0.0 1.0 2.4 0.6 1.8 0.5 0.4 0.1 0.4 0.8 0.5 0.3 0.4 7.0 1.1 0.5 0.4 1.2 0.6 4.8 4.5 4.1 6.4 4.7 6.2 6.2 7.9 5.4 4.8 5.9 5.1 7.1 3.2 13.1 17.9 32.5 4.2 15.6 17.0 7.4 24.8 13.7 10.4 2.1 24.3 25.5 16.5 29.2 16.5 21.6 4.4 9.8 14.4 7.3 6.2 8.6 10.9 13.8 19.4 12.2 17.9 12.7 8.3 12.8 5.9 8.2 20.4 13.6 3.6 9.7 18.5 13.0 9.1 16.2 21.8 16.5 4.8 11.5 19.8 10.6 14.0 16.7 11.3 36.0 24.1 14.0 17.6 7.8 9.8 10.0 12.5 15.4 4.9 14.0 21.4 6.6 7.6 8.7 12.2 11.8 8.6 5.7 40.2 20.5 10.7 6.7 31.1 ESCO2 "EFO2, RBS" ENSG00000171320 "Establishment of sister chromatid cohesion N-acetyltransferase 2" Q56NI9 8 27771949-27812640 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.0;intestine: 11.0;lymphoid tissue: 8.5;testis: 5.7" "Group enriched" "Detected in many" 4 "Erythroid cells: 44.6;Spermatocytes: 62.0;Spermatogonia: 80.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "T-reg: 1.3" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA027243, HPA053679" Supported "Nucleoplasm,Golgi apparatus,Cell Junctions" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Golgi apparatus" "Cell Junctions" "HPA027243: AB_2672175, HPA053679: AB_2682227" "unprognostic (7.86e-2)" "unprognostic (1.50e-2)" "prognostic favorable (1.04e-4)" "unprognostic (5.13e-3)" "unprognostic (9.50e-2)" "unprognostic (8.67e-3)" "unprognostic (7.30e-4)" "unprognostic (5.24e-3)" "unprognostic (2.24e-2)" "unprognostic (2.54e-2)" "unprognostic (7.51e-4)" "unprognostic (2.23e-1)" "unprognostic (1.65e-14)" "unprognostic (6.65e-3)" "unprognostic (5.32e-1)" "unprognostic (5.85e-2)" "unprognostic (4.06e-1)" 0.5 0.4 0.0 2.7 0.2 6.0 1.2 0.4 0.2 0.5 0.0 3.7 11.0 0.6 0.0 2.4 0.2 0.6 0.2 0.0 0.0 0.1 0.7 0.4 4.6 0.0 0.0 0.1 1.0 0.3 0.0 1.1 0.1 0.3 4.3 0.5 0.3 0.1 0.0 1.1 7.9 0.7 0.0 0.8 2.5 5.7 0.0 8.5 0.3 0.2 5.7 0.8 0.5 0.2 54.6 39.9 17.9 22.0 2.3 3.9 10.2 31.6 12.9 27.8 32.5 14.2 10.7 21.0 16.6 8.3 24.7 29.2 22.0 8.5 43.6 15.8 9.2 24.4 16.2 15.3 0.3 12.5 21.4 0.7 0.9 17.0 4.2 3.0 11.6 15.2 20.0 30.0 17.7 10.5 49.8 5.9 12.2 29.9 13.4 21.7 53.0 14.8 9.6 31.9 8.0 11.7 15.5 19.6 7.9 6.5 13.2 14.1 5.2 17.9 37.0 36.2 25.7 4.0 11.1 25.2 10.2 20.5 25.2 0.0 0.2 0.1 0.0 0.4 0.0 0.4 0.2 0.2 0.6 0.0 0.1 0.1 0.2 0.3 0.1 0.0 1.3 0.3 0.0 0.2 0.4 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.3 0.0 4.7 0.0 2.4 2.3 0.6 2.1 1.8 1.2 1.5 1.7 1.2 0.0 3.3 0.0 4.2 4.6 1.3 8.2 0.0 0.4 5.4 1.3 2.6 1.0 1.2 44.6 0.3 0.0 6.6 3.2 5.6 3.1 1.3 11.4 1.4 1.5 5.4 0.0 0.4 4.4 2.0 2.5 3.5 0.8 1.8 3.2 0.0 1.0 0.5 0.1 4.1 1.0 0.9 0.1 1.5 0.0 11.5 0.6 15.1 0.1 1.6 2.0 6.6 0.8 2.3 62.0 80.0 6.8 0.6 1.0 3.1 1.8 8.0 1.4 ESRRG "ERR-gamma, ERRg, NR3B3" ENSG00000196482 "Estrogen related receptor gamma" P62508 1 216503246-217137755 "FDA approved drug targets, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 49.6;parathyroid gland: 46.3;retina: 36.1;stomach 1: 35.1" "Group enriched" "Detected in many" 4 "Astrocytes: 330.7;Excitatory neurons: 415.2;Inhibitory neurons: 495.5;Oligodendrocyte precursor cells: 391.6;Oligodendrocytes: 218.7;Syncytiotrophoblasts: 214.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "RPMI-8226: 23.0;SH-SY5Y: 42.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044678 Uncertain Approved Nucleoplasm No NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA044678: AB_10963215" "unprognostic (6.48e-2)" "unprognostic (1.11e-1)" "unprognostic (7.06e-2)" "unprognostic (7.32e-2)" "unprognostic (2.34e-1)" "unprognostic (5.48e-2)" "unprognostic (1.66e-1)" "unprognostic (1.13e-1)" "unprognostic (4.55e-2)" "unprognostic (2.88e-1)" "unprognostic (2.35e-1)" "unprognostic (1.79e-2)" "prognostic favorable (1.13e-11)" "unprognostic (3.04e-1)" "unprognostic (2.55e-1)" "unprognostic (3.65e-4)" "unprognostic (2.05e-1)" 0.4 6.4 1.1 0.2 3.1 0.0 3.6 16.9 12.3 1.5 7.4 0.5 5.3 0.4 0.9 1.6 2.5 0.7 10.6 4.4 2.3 29.0 0.7 0.5 0.2 45.4 4.9 0.7 5.7 46.3 1.5 10.6 49.6 3.1 0.3 36.1 16.0 0.7 5.8 0.8 5.0 0.2 1.6 1.1 35.1 1.1 3.5 0.6 5.9 10.2 0.3 0.7 0.2 6.1 0.3 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 1.2 0.0 0.2 0.0 0.0 23.0 3.4 2.5 8.1 42.4 0.0 0.4 0.0 2.5 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 3.1 16.9 12.3 4.4 2.3 45.4 4.9 49.6 1.6 3.5 6.1 0.2 0.0 1.8 330.7 0.2 0.3 3.8 0.6 0.6 29.5 9.5 5.2 51.2 10.0 1.8 23.9 58.4 35.4 0.0 0.0 54.8 5.0 5.1 15.9 2.0 1.3 8.3 0.0 415.2 2.4 4.7 3.0 70.3 3.5 0.0 0.5 1.1 0.6 4.8 48.8 495.5 1.7 14.2 0.3 0.4 8.1 0.3 0.5 8.8 36.5 0.0 13.3 0.0 391.6 218.7 0.4 1.3 0.7 0.1 4.9 16.3 29.0 16.0 41.3 0.0 10.3 0.4 1.6 0.3 0.8 0.3 214.9 0.3 1.1 2.6 1.7 ETV1 ER81 ENSG00000006468 "ETS variant transcription factor 1" P50549 7 13891229-13991425 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 119.9;salivary gland: 91.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 137.7;Astrocytes: 67.3;Cardiomyocytes: 87.7;Enteroendocrine cells: 198.1;Excitatory neurons: 66.9;Oligodendrocyte precursor cells: 135.7" "Cancer enhanced" "Detected in all" "glioma: 22.5" "Group enriched" "Detected in all" 5 "cerebellum: 119.9;thalamus: 32.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 67.8;hTERT-RPE1: 76.2;SCLC-21H: 79.3;U-87 MG: 157.2;WM-115: 78.8" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 200.7" "HPA068389, HPA077249" Supported Approved Nucleoplasm No No "Cluster 35: T-regs - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA068389: , HPA077249: AB_2686829" "unprognostic (2.45e-1)" "unprognostic (1.01e-1)" "unprognostic (6.98e-2)" "unprognostic (1.04e-1)" "unprognostic (1.49e-2)" "unprognostic (2.13e-2)" "unprognostic (1.64e-7)" "unprognostic (7.08e-3)" "unprognostic (7.21e-2)" "unprognostic (2.36e-1)" "unprognostic (2.01e-1)" "unprognostic (3.02e-1)" "unprognostic (1.51e-3)" "unprognostic (2.21e-2)" "unprognostic (2.05e-1)" "unprognostic (1.05e-1)" "unprognostic (1.20e-2)" 4.9 23.0 13.6 1.9 10.9 0.2 8.2 119.9 12.1 2.3 0.1 4.1 2.2 4.4 2.3 2.7 1.5 17.3 35.6 14.6 5.6 3.2 3.9 28.7 1.4 4.6 14.0 1.4 3.1 11.5 7.4 3.5 9.0 5.5 4.3 4.5 91.6 12.6 0.8 1.9 3.5 3.5 3.1 9.1 2.6 8.9 32.8 4.7 12.2 2.5 1.9 2.7 1.5 8.1 0.1 4.9 35.5 67.8 12.1 35.4 0.1 3.2 12.1 2.0 8.0 0.0 16.6 0.0 3.6 5.6 9.8 0.4 1.5 3.8 4.3 0.9 1.6 2.1 3.1 0.0 7.1 12.3 4.5 10.7 0.0 23.3 1.9 76.2 15.3 1.1 11.0 0.6 14.6 0.0 0.1 0.0 53.2 2.1 36.5 0.0 21.5 2.9 23.7 0.4 79.3 15.6 0.0 1.2 19.6 12.2 1.2 0.5 8.6 7.0 2.2 13.8 13.4 12.2 4.1 0.0 157.2 0.8 78.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 13.6 10.9 119.9 12.1 14.6 5.6 4.6 14.0 9.0 3.1 32.8 8.1 16.0 19.2 137.7 67.3 0.0 1.0 2.8 0.9 13.6 4.9 5.8 23.6 87.7 28.6 0.7 3.7 0.0 0.6 0.1 0.8 5.9 3.6 25.4 1.3 3.9 11.1 198.1 0.8 66.9 0.9 0.4 17.7 1.1 2.0 2.5 0.2 2.9 13.1 3.4 5.0 45.3 2.4 0.0 7.2 1.6 8.7 1.5 0.7 12.4 28.1 0.0 12.6 0.0 135.7 4.3 0.9 0.1 34.6 1.2 0.6 0.0 3.0 1.4 0.6 19.7 17.4 12.6 1.2 2.1 3.1 1.3 0.3 2.2 9.7 1.2 0.3 ETV2 ER71 ENSG00000105672 "ETS variant transcription factor 2" O00321 19 35641745-35644871 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 5 "testis: 19.0" "Group enriched" "Detected in many" 10 "Early spermatids: 146.6;Late spermatids: 443.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in many" 6 "plasmacytoid DC: 24.4" "Lineage enriched" "Detected in all" 6 "dendritic cells: 24.4" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 71: Testis - DNA repair" "Cluster 17: WM-115 - Nervous system development" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (1.14e-1)" "unprognostic (3.24e-2)" "unprognostic (1.73e-1)" "unprognostic (5.44e-2)" "unprognostic (1.30e-1)" "unprognostic (2.53e-3)" "unprognostic (1.42e-1)" "unprognostic (2.77e-1)" "unprognostic (2.83e-1)" "unprognostic (2.69e-3)" "unprognostic (8.17e-3)" "unprognostic (1.18e-1)" "unprognostic (1.12e-1)" "unprognostic (4.20e-4)" "unprognostic (2.48e-1)" "unprognostic (1.41e-1)" "unprognostic (2.74e-1)" 1.5 2.1 0.6 0.7 0.6 0.5 1.2 2.2 1.0 1.8 0.6 1.5 2.0 0.9 0.1 3.6 1.0 0.3 0.7 0.6 0.8 1.8 2.7 1.1 0.6 0.9 0.7 1.4 3.6 1.2 1.3 0.3 0.9 1.5 0.4 0.4 2.3 0.6 0.2 3.4 1.5 0.3 0.7 1.0 1.7 19.0 0.6 0.4 1.1 0.0 0.2 1.0 2.1 0.6 1.4 1.9 1.2 1.5 1.4 2.7 0.2 0.5 0.8 1.4 2.2 0.7 0.7 0.2 2.0 1.0 0.3 0.5 0.1 1.0 0.1 2.3 2.3 2.6 1.1 1.3 2.4 0.8 3.4 2.4 2.0 0.7 1.1 0.8 0.4 0.8 0.8 1.0 0.8 1.7 1.2 0.8 0.1 2.3 0.6 1.7 3.1 2.0 2.1 1.3 1.6 1.1 1.7 0.3 3.0 0.3 1.2 3.0 0.4 4.2 2.1 2.3 1.7 1.1 2.5 0.4 2.0 0.9 4.1 0.0 2.2 1.1 3.1 3.3 3.4 2.3 3.8 3.9 2.6 1.2 2.1 2.7 0.8 1.0 3.8 24.4 3.3 1.8 0.6 0.6 2.2 1.0 0.6 0.8 0.9 0.7 0.9 0.7 0.6 0.6 2.4 0.0 1.1 0.0 2.8 5.7 3.5 8.4 12.0 5.1 9.0 12.2 1.4 4.3 2.6 5.5 0.0 1.9 7.0 12.1 7.9 1.9 146.6 1.7 2.7 2.4 7.7 1.7 0.0 5.3 2.8 3.3 2.6 3.4 1.3 1.0 4.6 19.9 2.2 0.0 0.1 9.7 2.0 2.0 5.1 443.3 9.0 2.8 1.8 0.0 2.0 3.1 1.0 0.0 0.1 1.7 4.8 2.6 8.4 3.3 28.6 20.9 1.1 2.8 0.0 6.7 2.3 6.7 2.8 11.3 12.9 1.9 3.6 3.5 7.1 6.1 EVPL EVPK ENSG00000167880 Envoplakin Q92817 17 76004502-76027306 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 281.2;skin 1: 147.4;vagina: 101.9" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 26.7;Squamous epithelial cells: 94.1;Suprabasal keratinocytes: 25.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 59.8;MCF7: 40.4;RT4: 87.8;SK-BR-3: 43.2;T-47d: 54.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002220, HPA053969" Enhanced Supported "Intermediate filaments,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments" Cytosol "CAB002220: AB_563701, HPA053969: AB_2682326" "unprognostic (2.10e-1)" "unprognostic (1.58e-1)" "unprognostic (1.41e-1)" "unprognostic (4.21e-1)" "unprognostic (1.05e-2)" "unprognostic (1.87e-2)" "unprognostic (1.70e-1)" "unprognostic (1.11e-1)" "unprognostic (1.94e-1)" "unprognostic (1.44e-1)" "unprognostic (7.40e-3)" "unprognostic (2.64e-1)" "unprognostic (2.40e-2)" "unprognostic (2.31e-1)" "unprognostic (3.47e-1)" "unprognostic (7.93e-2)" "unprognostic (3.09e-2)" 1.3 0.3 0.6 1.0 0.6 2.5 2.6 1.1 1.0 47.5 0.8 8.9 11.0 1.5 1.7 281.2 2.1 1.7 0.2 0.6 0.3 17.0 0.3 9.4 0.6 2.8 1.3 0.3 4.0 3.4 1.5 0.3 2.8 8.0 1.5 0.6 42.3 1.8 1.4 147.4 9.1 1.0 0.5 0.3 5.2 0.8 0.6 0.4 10.7 0.1 7.9 12.7 101.9 1.5 28.1 23.4 0.0 0.3 0.2 0.0 9.6 0.2 0.0 0.0 0.0 2.6 16.7 0.0 0.1 0.0 0.0 59.8 0.1 7.8 0.1 0.1 0.2 0.7 19.4 17.4 0.0 0.2 4.2 0.2 12.3 0.2 0.0 0.0 0.0 3.7 0.1 1.1 0.0 40.4 1.0 3.6 0.1 11.9 10.5 11.5 0.1 0.4 16.7 87.8 1.1 0.0 11.4 43.2 0.0 0.2 54.1 0.8 0.0 0.0 0.1 0.2 0.1 0.1 0.2 0.1 0.1 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.3 0.0 0.2 0.1 0.0 0.6 0.6 1.1 1.0 0.6 0.3 2.8 1.3 2.8 0.5 0.6 1.5 0.2 19.2 19.5 0.0 0.0 11.7 4.7 10.5 26.7 0.3 5.1 2.9 3.7 4.3 16.5 5.5 0.0 0.2 0.2 10.8 1.9 4.4 0.0 4.3 0.6 0.3 20.4 1.3 0.3 0.5 0.2 0.5 12.8 8.9 12.6 0.2 0.0 0.0 0.0 0.0 0.1 5.7 2.0 0.6 2.1 0.1 0.9 0.2 1.8 0.0 0.1 0.0 0.0 0.0 0.1 8.4 7.4 1.9 1.2 4.6 19.3 3.4 13.1 0.1 0.0 0.7 0.7 0.1 1.2 94.1 25.9 0.0 0.4 0.4 15.5 12.9 EXO1 "HEX1, hExoI" ENSG00000174371 "Exonuclease 1" Q9UQ84 1 241847967-241895148 "Predicted intracellular proteins" "DNA damage, DNA excision, DNA repair, Immunity, Meiosis" "DNA-binding, Endonuclease, Excision nuclease, Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 17.3;lymphoid tissue: 11.1" "Cell type enhanced" "Detected in some" "Early spermatids: 9.3;Erythroid cells: 7.4;Extravillous trophoblasts: 16.7;Plasma cells: 11.8;Spermatocytes: 9.3;Spermatogonia: 9.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA053079, HPA069738" Enhanced "Nucleoplasm,Nuclear bodies" NA Yes "Cluster 46: Basophils - DNA binding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nuclear bodies" "HPA053079: AB_2682037, HPA069738: AB_2732140" "unprognostic (6.33e-3)" "unprognostic (8.54e-3)" "unprognostic (9.47e-3)" "prognostic unfavorable (8.21e-4)" "unprognostic (2.43e-1)" "unprognostic (6.34e-2)" "prognostic unfavorable (6.94e-7)" "unprognostic (1.84e-3)" "prognostic unfavorable (2.04e-4)" "unprognostic (2.40e-2)" "unprognostic (4.81e-3)" "unprognostic (9.40e-2)" "unprognostic (0.00e+0)" "unprognostic (6.72e-2)" "unprognostic (2.29e-1)" "unprognostic (1.75e-1)" "unprognostic (3.57e-1)" 0.5 0.3 0.2 3.3 0.2 17.3 1.2 0.1 0.7 0.5 0.1 3.2 2.9 0.8 0.0 2.5 0.3 0.4 0.2 0.3 0.1 0.3 0.5 0.6 5.8 0.1 0.2 0.2 0.3 0.7 0.1 3.3 0.2 0.2 3.7 0.0 0.5 0.2 0.1 1.8 2.5 1.2 0.2 1.5 1.6 5.7 0.3 11.1 0.4 0.0 6.4 1.2 0.8 0.4 41.3 26.8 43.4 28.6 2.7 6.7 36.5 53.4 17.7 46.7 50.5 33.9 22.5 44.3 25.3 12.6 25.1 40.0 55.5 22.5 54.8 69.5 48.4 41.5 28.8 17.3 1.0 59.8 29.4 1.7 1.1 46.8 12.5 5.7 14.7 43.4 84.6 57.0 37.8 19.0 65.9 33.6 60.4 49.7 26.0 46.2 40.5 47.5 9.6 25.6 48.1 60.9 34.8 27.9 19.5 20.2 25.8 36.6 5.5 44.9 39.5 42.7 72.9 41.5 59.0 71.3 15.6 48.1 54.9 0.8 0.2 0.0 0.2 0.0 0.0 0.3 0.2 0.2 0.1 0.3 0.1 0.0 0.0 0.2 0.0 0.0 0.9 0.3 0.2 0.2 0.1 0.7 0.3 0.1 0.1 0.2 0.2 0.2 0.3 0.4 0.2 0.0 0.0 0.3 0.7 0.8 0.1 0.7 0.0 0.0 0.3 0.5 2.3 0.0 0.1 0.0 0.0 5.3 0.2 1.2 0.0 0.1 9.3 0.3 0.4 0.7 0.0 7.4 1.0 0.0 16.7 0.9 1.1 0.5 0.0 4.6 0.4 0.0 3.3 0.0 2.9 0.5 0.0 0.3 0.8 2.1 0.0 0.6 0.0 0.0 0.6 0.0 0.0 0.0 0.3 0.1 0.0 0.0 11.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.3 9.3 9.8 2.7 0.1 4.0 0.8 0.8 1.9 0.3 EXOC4 "KIAA1699, MGC27170, SEC8, SEC8L1, Sec8p" ENSG00000131558 "Exocyst complex component 4" Q96A65 7 133253073-134066589 "Plasma proteins, Predicted intracellular proteins, Transporters" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 238.6;Excitatory neurons: 334.2;Inhibitory neurons: 306.8;Microglial cells: 341.0;Oligodendrocyte precursor cells: 395.6;Oligodendrocytes: 345.9;Rod photoreceptor cells: 231.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031443, HPA031444" Approved Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Cytosol" NA NA 10000 "Cluster 27: Non-specific - Gene expression" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 46: Photoreceptor cells - Phototransduction" "Nucleoli, Nucleoli rim" "Nucleoplasm, Cytosol" "HPA031443: AB_10602496, HPA031444: AB_2673886" "unprognostic (1.70e-1)" "unprognostic (1.62e-2)" "unprognostic (2.05e-1)" "unprognostic (5.09e-2)" "unprognostic (1.03e-1)" "unprognostic (4.06e-3)" "unprognostic (8.63e-2)" "unprognostic (2.33e-1)" "unprognostic (4.40e-1)" "unprognostic (2.04e-1)" "prognostic unfavorable (6.19e-4)" "unprognostic (9.78e-3)" "prognostic favorable (6.85e-5)" "unprognostic (5.91e-2)" "unprognostic (2.18e-1)" "unprognostic (3.37e-1)" "unprognostic (3.35e-2)" 20.7 21.1 18.7 13.8 20.2 13.8 21.4 19.3 20.3 22.6 24.3 19.7 13.1 21.5 13.6 24.4 27.3 17.8 15.3 20.9 19.4 17.7 17.8 17.7 16.4 18.4 20.3 30.6 27.3 27.3 16.9 19.6 19.9 18.3 21.5 53.1 16.3 20.5 68.4 25.4 13.5 23.9 18.8 21.0 17.3 18.7 19.1 28.1 26.4 38.5 20.3 21.1 18.6 20.8 40.1 32.2 43.3 43.3 49.7 51.6 15.0 28.6 47.2 25.4 33.2 18.8 54.7 29.8 20.1 54.1 36.9 24.7 23.7 38.8 41.8 45.6 28.2 24.0 31.5 19.9 54.7 32.0 25.1 50.4 47.6 36.3 66.5 55.7 43.5 38.6 35.1 28.8 47.7 26.1 58.5 35.2 32.8 47.5 29.8 25.7 38.7 54.2 40.7 35.2 33.9 53.2 43.0 39.1 46.3 48.9 25.8 29.3 47.9 28.1 14.6 30.0 31.5 45.0 29.4 28.1 82.9 36.4 43.8 10.3 12.0 7.2 11.2 12.9 10.0 8.3 11.6 11.9 16.3 8.1 9.4 9.6 4.0 19.6 11.4 7.2 12.9 11.2 18.7 20.2 19.3 20.3 20.9 19.4 18.4 20.3 19.9 18.8 19.1 20.8 22.9 22.4 22.3 238.6 27.3 18.9 16.3 16.6 25.6 39.9 16.8 15.4 30.9 11.5 18.0 14.7 93.8 17.5 26.7 21.5 3.9 15.0 29.6 27.0 21.2 23.0 17.4 18.7 334.2 18.2 16.6 21.2 34.1 21.0 8.2 32.4 23.2 15.9 18.1 50.5 306.8 21.0 26.4 27.3 14.5 27.6 17.4 20.4 14.2 341.0 23.9 20.4 23.7 395.6 345.9 15.4 17.4 18.8 27.7 13.2 16.3 16.9 29.8 231.5 13.1 26.0 15.3 20.5 13.1 28.2 17.0 11.2 26.2 26.4 21.9 20.1 EXOSC5 "hRrp46p, MGC12901, p12B, RRP41B, RRP46, Rrp46p" ENSG00000077348 "Exosome component 5" Q9NQT4 19 41386374-41397359 "Predicted intracellular proteins" "rRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 124.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053150, HPA055677" Approved Enhanced Nucleoplasm,Nucleoli NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoli Nucleoplasm "HPA053150: AB_2682058, HPA055677: AB_2682882" "unprognostic (1.24e-1)" "unprognostic (5.68e-2)" "unprognostic (2.99e-1)" "unprognostic (2.53e-3)" "unprognostic (7.50e-3)" "unprognostic (5.74e-2)" "unprognostic (3.83e-3)" "unprognostic (9.23e-2)" "unprognostic (2.36e-1)" "unprognostic (1.54e-1)" "unprognostic (9.39e-2)" "unprognostic (2.35e-2)" "prognostic unfavorable (3.45e-7)" "unprognostic (6.84e-2)" "unprognostic (2.27e-1)" "unprognostic (7.79e-2)" "unprognostic (7.82e-2)" 12.9 19.4 18.6 14.1 20.2 17.4 14.0 18.9 26.1 12.5 15.1 13.3 11.4 11.3 4.2 21.4 15.1 6.6 16.8 18.8 17.8 9.9 21.7 7.3 22.0 20.8 18.4 14.3 28.6 5.9 7.2 7.4 19.2 11.0 7.2 2.3 16.4 8.4 41.7 23.0 10.8 7.2 19.0 14.3 13.6 11.4 18.3 14.8 11.6 23.1 11.8 14.7 13.9 22.1 58.2 123.5 15.1 48.8 10.7 13.5 39.4 24.5 13.1 44.6 37.0 72.5 47.5 92.9 64.8 12.9 22.8 25.1 33.1 31.3 12.2 66.7 117.3 42.7 45.5 55.7 32.1 76.7 41.8 16.3 69.0 35.6 33.8 12.1 21.1 57.7 57.5 70.2 14.2 88.1 70.2 58.6 56.6 85.2 59.9 66.9 40.9 94.8 17.6 43.1 64.4 47.8 34.6 62.4 68.2 10.5 31.1 95.6 16.2 45.9 37.4 30.1 76.9 109.6 138.5 106.3 34.9 116.0 39.0 15.2 68.2 1.9 41.3 77.7 47.9 66.0 43.3 40.9 110.1 74.0 63.2 55.4 5.0 62.1 48.6 118.7 37.0 48.6 18.6 20.2 18.9 26.1 18.8 17.8 20.8 18.4 19.2 19.0 18.3 22.1 16.1 3.2 4.8 2.3 21.3 30.5 29.0 29.6 44.9 5.5 30.1 44.2 8.4 22.8 16.9 18.4 4.2 28.4 23.5 12.7 37.2 21.7 9.1 5.5 16.7 11.1 8.5 28.0 5.0 21.4 124.0 13.1 16.3 9.1 5.1 24.7 7.1 20.3 28.8 6.7 4.8 18.4 20.3 11.8 13.3 8.5 16.8 18.9 14.2 2.8 18.9 7.0 18.6 4.0 4.3 17.2 15.3 12.4 21.3 28.0 6.6 34.9 12.7 4.1 6.6 17.8 16.0 17.0 33.1 47.4 33.2 21.2 17.0 31.5 34.2 23.8 FAAH2 "AMDD, FAAH-2, FLJ31204, RP11-479E16.1" ENSG00000165591 "Fatty acid amide hydrolase 2" Q6GMR7 X 57286706-57489193 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 75.7;Excitatory neurons: 110.2;Inhibitory neurons: 131.2;Oligodendrocyte precursor cells: 110.6;Oligodendrocytes: 105.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "T-reg: 16.7" "Lineage enriched" "Detected in many" 9 "T-cells: 16.7" "Cell line enhanced" "Detected in many" "CAPAN-2: 14.0;HDLM-2: 13.0;RPMI-8226: 26.6;U-266/70: 20.9;U-266/84: 11.4" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.37e-1)" "unprognostic (1.78e-2)" "unprognostic (7.68e-2)" "unprognostic (2.29e-2)" "unprognostic (1.02e-1)" "unprognostic (4.51e-2)" "unprognostic (7.93e-3)" "unprognostic (4.47e-2)" "unprognostic (1.94e-1)" "prognostic favorable (5.99e-4)" "unprognostic (1.77e-1)" "unprognostic (2.03e-1)" "prognostic favorable (2.47e-13)" "unprognostic (9.16e-3)" "unprognostic (2.27e-1)" "prognostic favorable (2.66e-4)" "prognostic favorable (6.83e-5)" 0.8 1.6 1.1 1.6 0.8 0.4 6.8 3.3 1.0 3.6 0.9 3.2 3.0 1.3 4.4 4.9 6.1 1.7 0.3 0.7 2.6 7.2 10.5 3.2 2.6 1.2 1.3 0.4 15.1 13.4 6.7 0.8 1.2 7.3 4.0 7.0 7.1 4.1 0.1 9.6 3.0 0.3 0.5 0.7 4.6 0.1 2.2 7.3 4.8 0.2 7.0 3.4 3.4 0.9 3.4 0.3 0.1 0.2 0.1 0.1 3.1 0.0 0.1 0.0 0.0 2.4 14.0 0.1 4.0 0.0 0.0 0.6 1.1 2.5 0.0 13.0 6.9 0.4 3.1 1.0 0.0 1.5 0.0 0.0 4.2 0.0 0.0 0.1 0.0 1.4 1.6 6.3 0.0 1.4 0.8 0.0 2.4 2.9 0.0 0.0 2.4 26.6 8.1 4.5 2.4 0.1 0.2 3.9 0.0 5.7 3.9 0.1 0.0 0.0 0.3 0.0 0.2 20.9 11.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.7 0.0 5.0 1.8 8.0 3.4 0.0 0.5 7.7 0.9 0.3 0.9 0.0 1.2 16.7 1.6 1.1 0.8 3.3 1.0 0.7 2.6 1.2 1.3 1.2 0.5 2.2 0.9 0.2 3.2 7.8 75.7 4.0 2.7 12.1 19.0 15.4 4.4 6.0 4.2 0.3 4.3 14.9 5.5 18.8 5.5 0.2 4.2 9.8 11.9 0.0 12.6 1.1 0.4 13.2 0.0 110.2 14.1 2.5 1.1 15.8 12.2 0.0 0.9 1.1 11.3 0.7 1.7 131.2 5.4 26.4 0.0 0.3 0.0 0.6 0.6 3.6 45.0 0.6 1.2 0.0 110.6 105.3 11.9 3.8 0.4 14.4 7.4 4.8 5.6 25.1 11.8 0.0 0.5 1.0 0.0 0.0 7.1 6.7 5.6 16.7 0.3 4.0 9.2 FAM110A "bA371L19.3, C20orf55" ENSG00000125898 "Family with sequence similarity 110 member A" Q9BQ89 20 833715-857463 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 71.2" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 71.7;Extravillous trophoblasts: 138.2;Langerhans cells: 74.2;Macrophages: 70.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "basophil: 543.5;eosinophil: 163.4;intermediate monocyte: 160.6;non-classical monocyte: 248.6" "Group enriched" "Detected in all" 9 "granulocytes: 543.5;monocytes: 248.6" "Cell line enhanced" "Detected in all" "SK-BR-3: 84.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB034110, HPA069240" Uncertain Uncertain Nucleoplasm,Vesicles,Cytosol Yes Yes "Cluster 10: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 51: Myeloid cells - Hemostasis" "Nucleoplasm, Vesicles" Cytosol "CAB034110: AB_1562838, HPA069240: AB_2686103" "unprognostic (6.33e-2)" "unprognostic (2.53e-2)" "unprognostic (1.57e-2)" "unprognostic (3.43e-2)" "unprognostic (1.81e-1)" "unprognostic (3.37e-2)" "unprognostic (4.90e-3)" "unprognostic (5.55e-2)" "unprognostic (6.01e-2)" "unprognostic (4.78e-2)" "unprognostic (2.35e-2)" "unprognostic (2.47e-1)" "prognostic unfavorable (4.42e-4)" "unprognostic (9.64e-3)" "unprognostic (1.17e-2)" "unprognostic (6.42e-3)" "unprognostic (4.21e-3)" 4.2 5.5 4.2 5.9 5.2 8.8 9.0 3.1 3.6 10.1 3.9 5.5 10.0 2.5 4.7 39.3 2.5 2.3 4.0 2.8 3.4 8.8 3.6 12.3 6.7 5.5 5.3 2.8 5.5 11.0 7.9 6.6 5.6 19.3 3.2 1.2 18.4 3.6 4.0 71.2 9.7 1.1 3.3 23.4 6.1 3.7 6.6 6.9 7.6 0.6 7.8 9.2 18.4 3.6 27.7 7.3 4.1 7.6 4.4 1.9 27.8 8.5 4.7 5.3 4.7 16.0 16.9 8.9 3.7 5.3 7.6 43.7 3.3 22.2 4.4 7.3 2.3 18.6 4.9 4.2 2.0 5.1 6.3 1.2 27.1 7.3 7.1 1.6 3.6 8.1 10.2 21.5 4.9 16.4 14.3 13.8 5.3 17.7 12.3 14.1 7.0 11.7 4.1 19.6 7.7 9.1 7.4 84.0 3.8 1.7 34.9 7.5 4.8 12.6 9.1 11.5 9.6 7.8 7.3 3.8 2.0 13.2 9.2 543.5 28.3 163.4 13.2 160.6 11.7 7.0 23.7 27.2 36.2 11.7 28.1 27.9 15.3 6.9 248.6 3.9 43.0 24.2 4.2 5.2 3.1 3.6 2.8 3.4 5.5 5.3 5.6 3.3 6.6 3.6 3.5 0.0 7.0 0.0 18.5 32.6 17.0 31.6 71.7 0.3 26.7 20.1 2.9 7.2 15.7 11.0 0.0 41.5 24.3 5.1 1.9 10.1 9.9 3.0 1.7 8.0 10.8 16.2 0.5 6.0 138.2 3.6 5.1 5.2 51.5 1.4 17.2 0.7 20.0 5.0 0.4 8.8 16.2 36.7 74.2 24.3 3.4 70.0 7.2 1.9 29.9 0.3 25.7 0.5 0.1 13.4 7.8 1.9 3.5 20.9 16.1 2.4 7.4 2.6 6.6 1.1 4.3 3.4 4.9 57.7 36.8 31.3 26.1 14.2 10.4 24.6 FAM111B CANP ENSG00000189057 "Family with sequence similarity 111 member B" Q6SJ93 11 59107185-59127412 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Hydrolase, Protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 18.0" "Cell type enhanced" "Detected in many" "B-cells: 12.8;Erythroid cells: 9.1;Plasma cells: 8.8;Squamous epithelial cells: 7.1;Undifferentiated cells: 10.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "memory B-cell: 3.3;naive B-cell: 2.6" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" HPA038637 Uncertain Approved Nucleoplasm,Cytosol No Yes "Cluster 37: B-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 55: Plasma cells - Humoral immune response" Nucleoplasm Cytosol "HPA038637: AB_10672522" "unprognostic (2.31e-1)" "unprognostic (2.68e-2)" "unprognostic (1.80e-3)" "unprognostic (6.94e-2)" "unprognostic (1.89e-1)" "unprognostic (1.96e-2)" "prognostic unfavorable (1.76e-4)" "unprognostic (1.49e-3)" "unprognostic (1.40e-2)" "unprognostic (4.85e-2)" "prognostic unfavorable (1.17e-5)" "unprognostic (1.01e-2)" "unprognostic (1.24e-5)" "unprognostic (2.94e-2)" "unprognostic (1.80e-1)" "unprognostic (1.20e-3)" "unprognostic (1.24e-1)" 0.9 0.5 0.5 5.9 0.6 4.8 2.7 2.8 1.8 1.0 0.1 5.6 3.4 1.0 0.5 3.4 0.5 0.8 0.3 0.6 1.1 0.4 2.5 1.1 12.3 0.5 1.0 0.2 0.6 0.9 0.0 1.7 0.7 1.0 5.8 1.3 0.8 0.4 0.4 4.4 4.0 2.0 0.1 1.8 3.2 0.8 0.6 18.0 0.9 0.1 13.3 1.7 1.0 2.1 72.6 18.5 26.6 0.4 2.7 4.9 0.3 53.5 26.7 31.2 46.1 38.7 28.0 89.8 35.4 15.7 26.3 54.7 39.5 36.2 55.2 46.8 9.5 9.8 32.3 16.9 0.1 0.3 11.1 1.2 1.2 30.3 2.4 6.0 16.9 24.1 2.8 81.9 37.2 27.3 57.7 0.6 0.3 43.2 21.0 60.1 39.7 34.7 16.8 61.2 5.2 16.9 44.4 50.8 8.7 9.7 56.2 5.0 9.4 24.1 52.4 73.5 49.6 62.6 48.4 0.6 35.0 0.4 35.4 0.2 0.1 0.1 0.1 0.0 0.1 3.3 0.2 0.3 0.1 2.6 0.1 0.1 1.6 0.0 0.1 0.1 0.7 0.1 0.5 0.6 2.8 1.8 0.6 1.1 0.5 1.0 0.7 0.1 0.6 2.1 0.7 0.0 0.0 0.0 12.8 4.2 2.2 4.2 1.8 0.0 2.5 4.2 0.3 0.0 1.4 0.0 0.0 1.1 1.4 4.0 0.0 0.8 0.0 0.9 1.6 1.2 0.0 9.1 0.0 0.0 0.4 1.5 3.6 1.9 0.0 6.3 0.0 0.2 3.9 0.0 0.0 4.4 2.0 0.3 1.6 0.0 0.0 2.4 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.6 1.3 0.0 8.8 0.7 0.5 0.1 1.6 0.0 0.0 1.3 1.8 0.1 1.0 7.1 2.7 0.1 3.2 1.1 10.4 1.6 FAM117B "ALS2CR13, FLJ38771" ENSG00000138439 "Family with sequence similarity 117 member B" Q6P1L5 2 202634969-202769757 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 45.8;Inhibitory neurons: 49.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003229, HPA028746" Uncertain Approved Nucleoplasm,Centrosome Yes No "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm Centrosome "HPA003229: AB_2246696, HPA028746: AB_2672760" "unprognostic (1.39e-2)" "unprognostic (1.47e-1)" "unprognostic (1.53e-2)" "unprognostic (4.59e-2)" "unprognostic (1.07e-2)" "unprognostic (4.07e-3)" "unprognostic (1.55e-2)" "unprognostic (4.84e-2)" "unprognostic (6.21e-2)" "unprognostic (2.55e-2)" "unprognostic (8.40e-3)" "unprognostic (5.75e-1)" "unprognostic (6.01e-2)" "unprognostic (8.93e-2)" "unprognostic (3.18e-1)" "unprognostic (8.59e-2)" "unprognostic (1.37e-3)" 3.1 7.5 5.1 4.5 5.4 2.9 3.3 7.0 7.1 2.7 0.7 4.9 4.3 2.9 2.9 5.4 3.8 3.0 1.8 5.0 6.3 4.9 1.9 2.9 7.2 3.1 3.8 5.1 4.6 7.3 3.5 6.9 3.6 5.1 4.7 2.6 3.3 3.0 1.5 5.0 3.7 2.0 3.3 5.4 4.1 5.8 6.4 9.6 2.8 1.8 7.4 3.8 3.2 4.1 2.0 2.4 10.5 7.2 3.5 1.9 10.2 0.6 0.9 0.6 1.1 3.1 4.2 8.2 6.5 1.2 1.6 1.9 9.0 4.6 1.7 0.2 7.2 6.9 4.3 11.6 2.8 5.9 3.0 2.6 6.3 1.3 1.9 4.7 2.8 10.8 10.1 1.6 0.6 3.9 16.1 12.1 10.7 5.8 4.5 12.5 2.1 9.8 5.5 5.2 17.7 15.4 8.0 5.3 3.9 8.7 2.2 8.1 1.7 1.2 2.4 1.9 1.1 5.9 3.6 10.8 2.4 4.5 1.3 0.4 3.9 1.5 1.3 8.2 3.4 8.1 3.0 2.7 4.5 7.7 8.2 5.7 2.2 4.4 9.1 1.5 1.2 3.1 5.1 5.4 7.0 7.1 5.0 6.3 3.1 3.8 3.6 3.3 6.4 4.1 9.7 3.2 7.5 13.1 21.5 17.2 2.9 3.0 12.0 4.9 8.1 4.3 4.9 12.8 2.6 18.4 4.2 8.4 8.8 11.7 0.0 10.2 2.2 8.6 6.5 4.9 25.8 3.0 45.8 6.4 6.3 6.1 7.1 10.1 5.7 15.3 8.2 2.2 2.8 6.7 49.7 11.8 2.0 27.4 13.9 1.4 13.1 17.1 3.6 23.4 17.1 1.7 3.1 29.1 29.4 5.8 9.7 23.7 5.2 6.7 4.9 5.9 3.0 2.7 6.6 2.0 4.1 5.0 16.3 29.2 19.9 2.7 10.1 11.1 13.8 6.0 FAM160A1 FLJ43373 ENSG00000164142 "Family with sequence similarity 160 member A1" Q05DH4 4 151409176-151670503 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 32.3;skeletal muscle: 34.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 11.9;Excitatory neurons: 15.8;Oligodendrocyte precursor cells: 19.1;Suprabasal keratinocytes: 14.5" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 11 "cerebellum: 13.8" "Immune cell enriched" "Detected in single" 14 "plasmacytoid DC: 2.5" "Lineage enriched" "Detected in single" 14 "dendritic cells: 2.5" "Cell line enhanced" "Detected in many" "A-431: 8.6;HeLa: 10.0;hTERT-HME1: 9.2;SiHa: 8.9;SK-BR-3: 7.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" HPA046348 Enhanced Approved Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 20: HeLa - Mitochondria" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA046348: AB_10966145" "unprognostic (1.96e-1)" "unprognostic (3.40e-1)" "unprognostic (1.21e-3)" "unprognostic (2.37e-2)" "unprognostic (2.54e-2)" "unprognostic (1.38e-1)" "unprognostic (5.33e-2)" "unprognostic (4.55e-2)" "unprognostic (1.52e-1)" "unprognostic (7.21e-3)" "unprognostic (1.30e-3)" "unprognostic (2.39e-1)" "unprognostic (1.51e-12)" "unprognostic (2.41e-2)" "unprognostic (2.34e-1)" "unprognostic (2.21e-1)" "unprognostic (1.28e-1)" 0.6 1.3 0.8 0.3 0.7 1.8 4.4 13.8 1.2 3.2 32.3 3.3 1.9 1.6 4.0 7.8 2.7 0.9 3.4 1.2 0.0 3.4 0.7 1.9 0.2 0.6 0.6 2.4 10.2 8.3 1.3 0.5 0.8 2.2 3.4 6.7 4.7 1.5 34.5 13.4 2.0 1.1 0.3 0.5 2.5 3.4 0.4 1.5 6.8 16.5 2.3 2.2 3.4 0.2 8.6 0.7 0.0 0.2 0.0 0.1 2.9 0.3 1.4 0.8 0.2 3.6 3.0 0.0 0.8 0.3 2.6 7.4 2.1 6.1 0.9 0.0 3.3 0.0 10.0 0.9 0.0 0.0 0.2 0.2 7.0 0.0 9.2 2.4 0.2 0.7 0.0 0.0 0.5 1.2 0.0 0.0 2.8 2.8 0.8 0.0 2.0 0.2 5.1 5.5 1.2 0.4 8.9 7.8 0.2 2.2 3.3 0.0 0.0 0.4 3.7 0.2 1.4 0.0 0.0 0.0 1.8 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.8 0.7 13.8 1.2 1.2 0.0 0.6 0.6 0.8 0.3 0.4 0.2 0.1 3.2 2.0 1.3 0.0 11.9 6.6 2.9 10.8 0.1 2.7 1.9 1.8 0.0 5.2 0.0 0.0 0.3 0.5 5.9 0.0 1.6 3.3 5.9 0.6 0.4 0.0 0.0 15.8 1.8 0.6 0.6 6.1 10.8 1.3 0.3 0.0 0.5 0.3 8.4 2.4 2.3 0.0 0.0 2.1 1.5 0.0 0.6 0.0 1.0 0.0 2.5 0.0 19.1 1.3 1.9 0.3 0.0 1.4 7.9 2.2 0.7 1.3 4.7 0.0 1.0 0.4 6.1 5.8 11.6 14.5 1.6 0.2 0.3 1.8 8.6 FAM174A "NS5ATP6, TMEM157, UNQ1912" ENSG00000174132 "Family with sequence similarity 174 member A" Q8TBP5 5 100535374-100586741 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial ciliated cells: 154.5;Respiratory ciliated cells: 222.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 7 "neutrophil: 55.8" "Lineage enriched" "Detected in all" 10 "granulocytes: 55.8" "Cell line enhanced" "Detected in all" "U-266/84: 61.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019539 Approved Approved "Golgi apparatus,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 30: Mammary glandular cells - Lactation" "Golgi apparatus" Cytosol "HPA019539: AB_2293743" "unprognostic (2.34e-1)" "unprognostic (2.90e-1)" "unprognostic (1.29e-1)" "unprognostic (9.02e-3)" "prognostic unfavorable (2.57e-6)" "unprognostic (5.55e-3)" "unprognostic (3.06e-1)" "unprognostic (2.60e-1)" "unprognostic (3.60e-2)" "unprognostic (1.30e-2)" "unprognostic (1.73e-2)" "unprognostic (7.69e-2)" "prognostic favorable (5.48e-4)" "unprognostic (1.74e-1)" "unprognostic (2.65e-1)" "unprognostic (1.50e-1)" "unprognostic (1.45e-1)" 16.1 23.1 13.0 8.1 14.4 2.8 15.3 13.4 16.5 11.4 23.3 12.6 11.2 12.1 12.1 24.3 34.8 7.5 19.5 13.8 18.6 17.3 15.7 17.2 5.6 13.9 14.0 10.1 22.6 29.3 27.4 15.1 14.9 18.2 8.5 16.8 17.4 11.8 42.8 30.3 10.3 8.0 13.9 10.2 15.5 22.0 14.6 5.3 13.6 24.7 5.4 13.0 16.9 14.6 10.3 10.7 4.3 13.6 10.3 8.4 15.1 23.1 12.9 9.3 12.7 2.2 13.1 1.8 46.2 10.1 16.2 8.6 3.6 15.1 7.0 12.8 10.9 1.3 18.6 6.4 13.9 5.3 12.4 10.7 35.4 7.2 5.5 21.3 14.3 5.3 3.8 13.7 15.9 20.7 1.6 11.1 2.4 1.2 29.1 3.6 16.2 18.2 17.0 12.3 8.6 23.4 16.2 14.5 13.7 5.0 13.9 11.5 16.1 11.7 7.4 19.0 18.5 44.3 61.5 2.4 14.5 7.1 10.4 7.9 4.9 7.1 3.3 5.5 5.1 2.8 3.3 4.0 4.4 3.3 2.9 3.8 55.8 5.5 5.7 4.4 4.4 3.3 13.0 14.4 13.4 16.5 13.8 18.6 13.9 14.0 14.9 13.9 14.6 14.6 40.8 32.1 31.8 13.1 13.8 88.1 31.4 80.3 43.3 29.7 57.3 31.2 17.4 34.3 54.7 29.5 4.2 44.5 10.0 17.8 43.0 30.6 33.2 154.5 13.8 27.1 34.8 20.6 26.0 30.0 40.3 26.9 18.8 25.3 13.3 8.1 35.0 30.6 23.5 30.3 38.3 32.3 85.5 16.8 22.1 10.1 18.0 14.1 49.8 15.9 17.1 75.4 6.2 19.1 25.1 30.2 23.3 24.5 60.7 28.1 23.2 40.0 222.5 42.3 13.1 48.7 24.3 91.5 20.7 59.6 115.1 50.3 13.8 18.4 18.9 43.1 FAM189A2 "C9orf61, X123" ENSG00000135063 "Family with sequence similarity 189 member A2" Q15884 9 69324567-69392558 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 48.3;thyroid gland: 58.2" "Group enriched" "Detected in many" 5 "Alveolar cells type 1: 157.0;Astrocytes: 256.3" "Cancer enhanced" "Detected in many" "thyroid cancer: 22.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 3.2;NTERA-2: 5.1;RPTEC TERT1: 1.8;RT4: 2.3;SK-MEL-30: 5.0;SuSa: 1.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029411, HPA057207" Approved NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 64: Astrocytes - Nervous system maintenance" "HPA029411: AB_10602338, HPA057207: AB_2683369" "unprognostic (2.04e-2)" "unprognostic (1.13e-1)" "unprognostic (1.45e-1)" "prognostic favorable (1.16e-6)" "unprognostic (2.24e-1)" "unprognostic (3.93e-2)" "unprognostic (3.47e-2)" "unprognostic (2.89e-2)" "unprognostic (2.09e-1)" "unprognostic (2.71e-3)" "unprognostic (7.84e-2)" "unprognostic (1.07e-2)" "prognostic favorable (1.75e-5)" "unprognostic (3.42e-1)" "unprognostic (2.41e-1)" "unprognostic (4.82e-2)" "unprognostic (1.14e-1)" 6.0 4.7 12.8 0.4 15.0 0.0 13.7 15.8 11.2 26.0 9.2 7.1 1.2 6.8 1.7 5.2 6.8 1.6 13.3 12.2 15.7 4.7 0.2 22.3 0.6 20.1 16.7 24.6 7.3 6.0 7.6 1.5 17.1 11.1 1.1 4.4 6.2 3.4 48.3 12.4 4.0 4.9 16.3 0.4 13.7 1.3 19.8 5.6 58.2 9.0 0.9 7.9 4.6 15.1 0.0 0.0 0.2 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.8 0.7 0.7 0.0 0.0 0.6 1.6 0.1 1.4 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 5.1 0.3 0.0 0.0 0.1 0.0 1.8 2.3 0.0 0.0 0.0 0.0 5.0 1.9 0.1 0.0 0.7 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.8 15.0 15.8 11.2 12.2 15.7 20.1 16.7 17.1 16.3 19.8 15.1 12.1 157.0 23.3 256.3 0.4 3.3 4.9 1.9 7.4 2.1 18.4 39.6 14.6 0.0 26.9 1.8 0.0 1.2 0.4 1.5 0.0 0.9 0.1 19.9 2.8 8.0 0.0 0.0 0.7 0.6 0.1 1.7 11.7 33.0 0.0 2.0 2.2 0.0 0.3 0.0 3.9 0.4 0.0 0.3 1.3 0.0 0.0 0.4 19.6 20.6 0.0 35.1 0.0 7.1 2.1 3.5 1.2 0.0 0.2 3.7 0.2 0.2 2.3 1.0 0.0 3.8 3.8 0.1 0.6 1.9 2.4 0.3 1.0 0.7 0.7 1.8 FAM234B KIAA1467 ENSG00000084444 "Family with sequence similarity 234 member B" A2RU67 12 13044381-13142521 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 22.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 29.8;Breast glandular cells: 16.8;Collecting duct cells: 18.4;Erythroid cells: 13.2;Spermatogonia: 13.7" "Cancer enhanced" "Detected in all" "breast cancer: 16.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010803, HPA010850" Approved Approved "Endoplasmic reticulum" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 58: Brain - Synaptic function" "Cluster 12: NES - Nervous system development" "Cluster 30: Mammary glandular cells - Lactation" "Endoplasmic reticulum" "HPA010803: AB_1079200, HPA010850: AB_2732402" "unprognostic (1.85e-3)" "unprognostic (1.99e-1)" "unprognostic (1.93e-3)" "unprognostic (2.92e-2)" "unprognostic (1.29e-1)" "unprognostic (8.03e-3)" "unprognostic (3.34e-2)" "unprognostic (1.37e-1)" "unprognostic (9.55e-2)" "unprognostic (3.40e-2)" "unprognostic (3.62e-2)" "unprognostic (1.63e-1)" "unprognostic (1.85e-3)" "unprognostic (5.22e-2)" "unprognostic (1.06e-1)" "unprognostic (4.06e-3)" "unprognostic (7.62e-2)" 3.3 2.5 14.1 1.6 14.7 3.0 16.4 9.2 22.9 2.3 4.5 1.5 1.8 2.5 3.1 2.0 2.9 1.6 1.8 15.5 16.1 5.4 2.2 2.7 1.6 10.5 10.7 2.5 2.6 3.3 5.1 5.7 11.5 6.2 1.1 17.6 2.7 2.4 2.2 12.7 1.8 2.3 8.1 2.2 1.6 5.6 11.7 2.3 8.6 1.7 1.5 2.5 2.6 13.4 3.6 3.6 10.9 7.7 8.3 8.0 8.4 2.4 2.8 5.3 10.4 3.8 5.3 14.7 2.9 2.9 9.4 5.4 13.9 2.6 11.0 1.7 7.7 8.7 4.1 3.0 4.4 7.6 4.7 6.3 5.5 7.8 5.9 8.0 7.2 10.2 2.2 5.1 5.8 12.2 6.5 4.8 14.3 2.8 2.0 8.5 14.0 1.6 3.3 8.9 15.0 4.9 5.3 3.5 4.3 18.5 4.4 4.2 3.5 3.5 5.8 6.5 2.6 2.8 3.9 9.4 11.1 3.4 4.4 0.2 1.4 1.1 1.3 2.6 1.8 2.4 1.5 1.3 1.2 3.4 2.1 2.3 0.3 1.5 4.2 2.3 1.2 0.7 14.1 14.7 9.2 22.9 15.5 16.1 10.5 10.7 11.5 8.1 11.7 13.4 5.4 3.2 3.3 0.0 2.2 0.0 2.1 0.0 1.2 29.8 16.8 3.6 0.0 2.8 0.0 18.4 2.1 9.6 1.0 0.0 1.9 2.0 9.3 1.1 1.0 3.2 12.2 13.2 0.0 1.3 3.4 1.9 0.5 1.5 0.0 2.0 5.0 2.3 3.6 3.3 0.0 0.8 0.0 1.6 0.0 3.6 5.6 1.5 0.0 0.0 2.3 4.2 1.0 0.0 0.0 1.1 1.2 5.3 1.9 3.3 2.6 1.2 0.0 3.3 0.0 1.6 1.3 9.2 13.7 2.2 0.0 3.6 1.3 1.2 0.9 1.5 FAM81A MGC26690 ENSG00000157470 "Family with sequence similarity 81 member A" Q8TBF8 15 59372693-59523555 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.0" "Group enriched" "Detected in many" 5 "Collecting duct cells: 31.3;Excitatory neurons: 83.0;Inhibitory neurons: 67.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "myeloid DC: 5.1;plasmacytoid DC: 11.7" "Lineage enriched" "Detected in many" 5 "dendritic cells: 11.7" "Cell line enriched" "Detected in many" 4 "Daudi: 66.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001847, HPA065797" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm Cytosol "HPA001847: AB_2666462, HPA065797: AB_2685560" "unprognostic (3.43e-3)" "unprognostic (4.47e-3)" "unprognostic (1.93e-1)" "unprognostic (1.32e-3)" "unprognostic (2.15e-1)" "unprognostic (1.30e-2)" "unprognostic (1.53e-2)" "unprognostic (1.43e-1)" "unprognostic (2.39e-1)" "unprognostic (8.90e-2)" "unprognostic (4.68e-2)" "unprognostic (2.13e-1)" "unprognostic (9.95e-3)" "unprognostic (1.08e-2)" "unprognostic (6.53e-2)" "unprognostic (3.76e-1)" "unprognostic (7.80e-2)" 0.4 0.1 7.0 2.4 10.5 0.2 1.4 0.0 17.0 6.7 0.5 4.3 2.4 2.4 4.4 0.4 6.1 1.6 1.5 11.0 3.2 6.8 0.4 0.7 4.9 0.0 0.1 0.6 1.9 1.1 2.6 0.8 0.1 2.3 5.2 1.3 2.6 1.5 0.5 0.9 1.4 1.2 0.0 1.4 2.4 1.8 6.0 0.4 2.1 2.8 5.5 0.4 0.4 8.3 10.5 15.0 1.1 0.2 0.4 0.2 6.0 0.6 0.0 1.0 2.8 1.8 1.7 66.5 0.3 0.2 14.1 7.8 8.3 2.5 1.9 0.7 4.3 0.0 10.6 0.8 0.0 5.7 1.3 0.0 1.5 0.4 0.8 0.8 0.1 2.7 0.1 0.0 1.0 3.5 0.1 0.1 0.9 2.7 5.4 1.5 14.8 1.7 3.3 3.8 3.0 0.8 6.0 0.3 9.9 0.6 2.5 3.4 0.3 2.4 7.4 2.9 11.4 0.1 0.0 0.8 2.5 2.2 6.7 0.0 0.5 0.0 0.0 0.0 0.0 0.9 0.0 0.0 5.1 2.3 0.0 0.0 0.3 0.1 0.0 11.7 0.0 0.3 7.0 10.5 0.0 17.0 11.0 3.2 0.0 0.1 0.1 0.0 6.0 8.3 0.2 0.0 1.3 11.4 2.5 0.5 1.4 0.2 0.6 0.0 2.4 2.4 6.9 0.0 1.0 31.3 0.0 0.1 0.0 1.7 5.9 0.5 0.5 11.2 0.9 0.7 1.2 1.3 83.0 0.2 1.6 0.6 1.1 1.5 1.3 0.2 0.4 0.2 1.3 10.1 67.0 1.9 2.0 0.6 1.5 1.4 0.3 0.7 8.8 4.7 0.7 1.1 0.0 2.5 8.1 0.4 1.9 0.0 1.2 1.4 0.8 0.3 8.4 0.2 0.0 1.1 3.1 0.2 1.6 1.5 0.4 0.0 0.4 0.2 4.0 1.0 FAM83F ENSG00000133477 "Family with sequence similarity 83 member F" Q8NEG4 22 39994954-40043534 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 20.3;testis: 40.8" "Cell type enhanced" "Detected in many" "Late spermatids: 68.1;Proximal enterocytes: 39.9;Suprabasal keratinocytes: 34.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 12.1;HaCaT: 12.8;HBEC3-KT: 15.5;hTCEpi: 37.9;hTERT-HME1: 11.8;OE19: 17.6;RT4: 18.6;SCLC-21H: 39.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA051207, HPA064657" Enhanced Approved Nucleoplasm,Mitochondria NA NA "Cluster 10: Basophils - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria Nucleoplasm "HPA051207: AB_2681388, HPA064657: AB_2685313" "unprognostic (2.78e-2)" "unprognostic (3.91e-2)" "prognostic favorable (1.73e-4)" "unprognostic (5.36e-2)" "unprognostic (1.48e-5)" "unprognostic (1.39e-2)" "unprognostic (1.75e-1)" "unprognostic (4.75e-2)" "unprognostic (4.79e-1)" "unprognostic (2.48e-1)" "prognostic favorable (9.40e-4)" "unprognostic (3.25e-1)" "unprognostic (1.10e-7)" "unprognostic (2.93e-1)" "unprognostic (2.37e-1)" "unprognostic (2.98e-2)" "unprognostic (8.32e-2)" 1.2 0.1 0.2 0.5 0.1 1.2 4.7 0.3 0.2 2.6 0.1 5.3 3.2 0.2 2.5 20.3 1.2 0.5 2.0 0.2 0.1 4.0 2.9 0.2 0.0 0.1 0.1 0.3 13.5 5.4 1.2 0.1 0.1 9.0 3.2 0.4 8.2 6.6 0.1 18.8 7.6 0.1 0.0 0.0 6.8 40.8 0.3 0.9 5.9 0.2 1.1 2.6 7.0 0.3 8.3 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 12.1 2.3 0.0 0.0 0.0 0.0 12.8 0.0 15.5 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 37.9 0.0 11.8 0.0 0.0 2.0 0.0 0.1 0.0 0.0 0.0 0.1 2.1 17.6 0.0 0.0 0.0 0.1 0.3 18.6 39.8 0.0 0.3 3.4 0.0 1.3 2.3 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.3 0.2 0.2 0.1 0.1 0.1 0.1 0.0 0.3 0.3 1.1 0.0 0.0 0.0 0.5 28.7 14.5 18.0 23.9 1.2 19.1 10.4 5.2 12.8 7.4 23.9 0.0 0.2 0.0 33.1 3.9 9.6 28.4 6.2 0.5 1.0 13.1 0.4 0.2 15.1 0.2 1.0 10.7 6.5 1.3 0.2 0.0 2.2 0.2 0.0 0.2 21.0 14.2 0.6 2.9 68.1 1.8 0.5 1.8 0.0 0.0 0.9 0.0 0.5 0.1 12.5 21.6 2.2 0.2 16.3 39.9 5.9 6.4 0.6 0.0 1.1 1.3 12.4 1.8 30.6 34.5 1.4 0.8 0.4 15.6 17.8 FAM98C FLJ44669 ENSG00000130244 "Family with sequence similarity 98 member C" Q17RN3 19 38403135-38409088 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 100.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040930, HPA041730" Approved Approved Nucleoplasm,Nucleoli,Cytosol No No "Cluster 26: Non-specific - Mitochondria" "Cluster 27: Brain & Skin - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" "Nucleoplasm, Nucleoli" Cytosol "HPA040930: AB_10795484, HPA041730: AB_10804114" "unprognostic (3.01e-2)" "unprognostic (6.44e-3)" "unprognostic (5.15e-2)" "unprognostic (1.94e-1)" "unprognostic (3.18e-1)" "unprognostic (8.10e-3)" "unprognostic (3.06e-1)" "unprognostic (2.15e-2)" "unprognostic (2.95e-1)" "prognostic unfavorable (8.51e-5)" "unprognostic (2.82e-2)" "unprognostic (8.91e-3)" "unprognostic (1.01e-1)" "unprognostic (2.37e-3)" "unprognostic (2.43e-1)" "unprognostic (2.96e-1)" "prognostic favorable (5.53e-4)" 10.6 9.6 14.5 5.5 13.9 8.7 12.3 12.3 17.6 14.8 7.2 14.6 13.8 10.7 2.6 17.7 12.3 5.3 11.6 13.8 11.7 12.2 13.3 9.1 6.2 18.9 11.6 12.5 18.6 8.4 11.6 2.3 13.5 13.4 4.7 1.7 13.9 5.8 3.3 25.2 15.4 3.3 12.7 11.8 14.4 9.0 14.4 4.7 11.4 2.5 3.8 12.7 14.6 14.3 15.6 16.3 1.9 9.4 2.0 6.8 8.2 8.8 7.3 8.5 8.9 2.8 11.0 13.9 9.7 5.2 3.0 7.5 3.7 6.3 1.4 22.6 7.6 4.6 2.9 6.5 9.0 3.9 8.1 6.6 13.0 4.3 7.8 4.7 5.0 22.5 12.9 15.0 5.1 17.2 5.9 3.1 1.4 25.5 17.5 11.6 3.9 8.4 10.4 8.0 3.3 9.6 8.8 15.6 5.6 0.9 11.8 12.3 6.7 3.8 10.4 11.9 10.7 16.1 8.8 6.1 9.9 9.2 6.2 0.0 1.9 10.8 2.4 2.7 3.2 2.0 4.2 3.4 2.6 6.5 3.3 2.6 1.7 3.0 2.7 1.0 3.9 1.4 14.5 13.9 12.3 17.6 13.8 11.7 18.9 11.6 13.5 12.7 14.4 14.3 19.8 9.6 8.9 3.6 17.5 21.5 22.3 23.7 14.8 15.1 21.1 26.3 5.4 10.0 21.2 23.9 12.5 11.8 22.1 41.4 21.5 22.2 6.4 18.2 9.1 12.0 25.7 9.7 11.7 32.9 10.9 13.9 17.9 18.0 15.2 8.6 11.4 12.5 11.0 11.8 9.5 32.4 22.4 13.2 18.2 2.4 18.6 14.3 23.2 2.8 14.4 14.6 34.0 5.5 8.5 23.8 42.8 18.4 12.7 12.2 100.4 22.6 22.4 12.5 13.1 13.5 13.8 37.4 37.4 22.3 29.8 6.2 21.8 12.9 34.8 23.4 FANCB "FAAP95, FAB, FLJ34064" ENSG00000181544 "FA complementation group B" Q8NB91 X 14835961-14873069 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "Fanconi anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 3.4;brain: 3.8" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 12.4;Oligodendrocytes: 33.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA003124 Uncertain NA NA "Cluster 37: B-cells - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "HPA003124: AB_1078813" "unprognostic (3.49e-2)" "unprognostic (1.92e-3)" "unprognostic (1.16e-2)" "unprognostic (8.42e-3)" "unprognostic (7.99e-2)" "unprognostic (2.42e-2)" "unprognostic (4.05e-5)" "unprognostic (6.93e-3)" "unprognostic (1.77e-3)" "unprognostic (7.70e-3)" "unprognostic (2.76e-4)" "unprognostic (1.03e-1)" "unprognostic (1.25e-11)" "unprognostic (4.46e-2)" "unprognostic (1.92e-1)" "unprognostic (6.88e-2)" "unprognostic (5.96e-2)" 0.2 0.1 2.1 0.7 3.3 3.4 0.5 1.2 1.6 0.3 0.0 0.3 0.2 0.3 0.1 0.4 0.2 0.1 0.1 0.8 1.0 0.1 0.1 0.2 1.2 1.7 2.2 0.4 0.1 0.1 0.0 0.8 1.8 0.2 0.5 0.0 0.2 0.1 0.1 0.3 0.2 0.3 1.5 0.4 0.2 0.2 3.1 1.4 0.2 0.1 1.3 0.3 0.3 3.8 7.3 5.0 4.8 3.9 0.3 1.1 1.7 11.2 3.0 8.8 9.9 3.5 5.3 10.6 1.9 4.4 6.6 7.0 11.3 4.1 15.0 5.1 5.9 4.1 7.9 1.7 0.1 5.8 3.3 0.1 0.4 9.0 2.0 0.9 4.4 3.5 7.3 7.2 5.2 3.5 5.7 3.2 6.1 3.0 7.1 5.1 11.4 5.2 0.8 2.6 3.1 3.5 5.7 2.4 3.2 11.2 3.6 2.0 1.8 6.7 3.7 14.5 6.8 1.8 3.9 7.2 3.0 4.1 14.3 0.3 0.2 0.2 0.2 0.1 0.1 0.7 0.1 0.3 0.2 0.5 0.1 0.1 0.4 0.4 0.1 0.2 0.4 0.2 2.1 3.3 1.2 1.6 0.8 1.0 1.7 2.2 1.8 1.5 3.1 3.8 1.9 3.2 0.5 1.0 5.2 1.7 1.1 1.5 0.6 3.0 1.6 3.3 0.4 0.0 1.8 0.0 0.0 7.0 6.2 0.9 0.0 1.2 0.4 2.1 2.7 1.9 0.0 5.0 6.3 1.5 12.4 2.0 1.5 2.3 3.8 6.6 1.4 0.3 3.6 3.3 4.8 0.8 4.1 0.3 1.8 0.6 1.2 2.7 0.0 2.8 1.0 0.4 3.1 3.0 33.1 0.7 0.1 1.2 6.5 0.7 0.2 0.4 1.2 0.5 0.0 2.4 2.3 5.2 4.2 3.8 1.0 3.8 4.1 0.7 1.8 1.5 FANCE "FACE, FAE" ENSG00000112039 "FA complementation group E" Q9HB96 6 35452338-35467102 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "Cancer-related genes, Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 22.1;Extravillous trophoblasts: 104.8;Syncytiotrophoblasts: 46.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB014893 Enhanced Supported Nucleoplasm NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 32: U-937 - Innate immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "CAB014893: " "unprognostic (2.66e-1)" "unprognostic (8.01e-3)" "unprognostic (7.73e-2)" "prognostic unfavorable (6.25e-4)" "unprognostic (1.99e-1)" "unprognostic (2.80e-3)" "prognostic unfavorable (2.08e-9)" "unprognostic (8.90e-2)" "unprognostic (5.70e-3)" "unprognostic (8.41e-2)" "unprognostic (1.52e-1)" "unprognostic (2.91e-2)" "unprognostic (1.28e-1)" "unprognostic (1.70e-1)" "unprognostic (3.05e-1)" "unprognostic (2.44e-2)" "unprognostic (5.14e-2)" 4.6 1.5 2.6 3.2 2.5 5.8 5.0 2.8 3.1 7.1 2.0 3.1 2.1 3.7 3.4 8.6 4.8 1.5 3.3 2.3 2.9 2.1 1.3 4.1 4.5 2.7 2.6 7.8 3.5 4.0 3.1 9.3 2.6 3.8 3.0 1.8 4.3 2.7 11.0 13.8 3.5 3.1 2.4 3.8 3.4 8.7 2.7 2.6 3.0 3.1 5.7 4.0 7.7 2.7 9.9 4.2 12.8 27.6 9.2 15.9 34.6 11.4 9.6 14.8 12.1 11.1 5.3 33.0 7.5 6.7 11.2 7.2 13.7 9.8 13.9 11.0 11.9 23.8 11.7 6.8 4.8 12.6 8.2 10.1 28.6 17.7 27.7 3.9 8.7 12.6 21.3 11.6 12.2 11.4 5.8 16.6 4.7 10.6 7.0 18.8 12.3 12.1 3.1 10.0 12.1 11.4 6.4 9.1 10.0 11.9 8.8 43.7 5.6 16.7 14.5 10.9 18.1 7.4 29.3 11.6 3.9 24.3 16.8 0.0 0.2 0.2 0.4 0.1 0.7 0.1 0.6 0.9 0.1 0.5 0.3 0.3 0.0 0.5 0.1 0.4 0.3 0.2 2.6 2.5 2.8 3.1 2.3 2.9 2.7 2.6 2.6 2.4 2.7 2.7 7.0 6.4 0.0 1.0 2.4 8.8 4.1 4.7 1.8 1.1 2.0 2.8 2.7 0.0 1.6 0.0 0.0 22.1 2.0 1.6 0.0 1.7 0.3 1.9 2.4 3.7 1.2 2.5 0.4 0.8 104.8 2.8 1.1 3.4 0.0 5.2 1.4 0.7 6.0 0.0 0.9 3.6 0.0 0.8 1.3 0.6 1.5 1.4 1.8 2.8 0.5 1.9 1.0 0.5 1.0 1.1 0.4 0.7 3.1 5.8 1.1 0.3 0.1 2.0 0.0 4.0 3.4 8.2 13.2 4.6 7.1 46.7 2.2 3.4 4.4 3.5 FBLN2 ENSG00000163520 "Fibulin 2" P98095 3 13549125-13638422 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 292.8" "Cell type enhanced" "Detected in many" "Adipocytes: 92.7;Endometrial stromal cells: 84.4;Fibroblasts: 458.4;Leydig cells: 170.9;Peritubular cells: 227.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 6.7;naive CD8 T-cell: 3.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 384.0;fHDF/TERT166: 264.3;HMC-1: 311.6;HSkMC: 221.9;U-2197: 139.2" "Group enriched" "Detected in many" 4 "olfactory bulb: 12.4;white matter: 3.1" "Low region specificity" "Detected in all" "HPA001934, CAB018622" Enhanced Supported "Plasma membrane" "Secreted to extracellular matrix" NA NA 35000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "CAB018622: AB_2294196, HPA001934: AB_1078827" "unprognostic (1.19e-1)" "unprognostic (7.76e-2)" "unprognostic (3.21e-1)" "prognostic unfavorable (9.48e-4)" "unprognostic (2.82e-2)" "unprognostic (1.05e-1)" "prognostic favorable (3.17e-4)" "unprognostic (8.02e-2)" "unprognostic (1.72e-1)" "unprognostic (1.70e-2)" "unprognostic (2.57e-1)" "unprognostic (4.66e-2)" "unprognostic (2.13e-2)" "unprognostic (1.89e-2)" "unprognostic (2.82e-2)" "unprognostic (2.61e-2)" "unprognostic (1.41e-1)" 157.3 7.6 5.9 12.7 7.7 1.0 97.3 5.2 9.0 63.4 6.4 32.7 6.2 31.1 3.2 42.4 26.8 46.2 292.8 7.0 4.9 8.7 3.7 29.2 8.4 5.3 5.3 5.8 8.6 3.0 2.3 80.3 4.8 29.1 11.8 0.6 39.4 8.8 47.7 72.5 19.8 14.7 4.1 6.0 22.3 46.7 6.9 14.2 63.7 48.9 5.6 79.6 56.7 4.4 0.0 1.4 50.9 0.0 384.0 51.7 23.8 124.9 98.2 122.4 80.4 8.1 0.3 0.0 5.9 264.3 0.2 0.2 0.0 0.5 22.9 0.1 0.1 100.7 1.9 0.0 26.0 0.2 311.6 221.9 2.0 19.3 0.0 0.2 0.0 8.6 0.8 0.9 0.6 0.3 5.2 0.6 12.2 0.0 0.7 0.2 0.0 0.5 0.9 0.1 3.0 2.4 0.5 90.3 0.1 13.6 0.2 0.3 0.1 0.1 0.1 139.2 0.1 0.2 0.0 0.0 1.1 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.2 6.7 1.3 0.0 3.7 0.0 0.2 0.0 0.5 0.0 0.9 5.9 7.7 5.2 9.0 7.0 4.9 5.3 5.3 4.8 4.1 6.9 4.4 92.7 0.0 1.5 1.6 3.6 30.8 0.8 10.5 2.2 0.0 1.7 1.9 8.8 0.0 12.3 7.3 2.1 7.8 1.9 0.1 0.0 0.0 3.8 2.9 84.4 43.8 0.0 1.7 0.6 0.2 4.8 458.4 6.1 2.7 23.6 0.6 47.8 0.4 3.6 0.0 0.6 0.0 0.0 1.9 49.8 12.1 170.9 4.5 39.2 26.2 0.3 1.2 0.0 30.7 0.3 0.3 0.0 227.2 1.6 1.2 2.7 0.1 1.4 0.4 13.1 29.7 26.4 3.4 13.5 2.0 28.8 6.2 5.3 0.2 0.0 1.1 FBRS "FBS, FBS1, FLJ11618" ENSG00000156860 Fibrosin Q9HAH7 16 30658431-30670810 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 109.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044117 Approved Approved Nucleoplasm NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 71: Testis - DNA repair" "Cluster 6: T47d - Mammary gland" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA044117: AB_10794394" "unprognostic (1.87e-1)" "unprognostic (8.48e-3)" "unprognostic (2.41e-2)" "unprognostic (9.52e-3)" "unprognostic (1.03e-1)" "unprognostic (4.80e-2)" "unprognostic (2.07e-3)" "unprognostic (7.01e-3)" "unprognostic (6.32e-2)" "unprognostic (7.65e-2)" "unprognostic (4.57e-3)" "unprognostic (1.01e-1)" "unprognostic (1.25e-2)" "unprognostic (2.13e-1)" "unprognostic (4.16e-1)" "unprognostic (1.42e-1)" "unprognostic (1.63e-1)" 25.6 34.3 23.0 24.4 22.2 55.9 25.8 21.5 24.6 34.2 14.9 39.1 21.2 35.6 5.5 57.2 36.0 9.4 28.7 22.9 19.7 33.3 29.9 29.2 21.8 24.7 20.9 33.8 29.8 16.6 57.6 12.6 19.4 37.3 6.5 6.5 30.2 15.6 38.4 53.5 40.0 9.7 16.8 53.4 33.8 117.3 22.9 21.3 36.6 11.4 15.9 34.7 33.2 23.0 28.8 30.2 15.6 12.9 15.3 15.5 39.5 20.9 16.9 17.7 13.3 17.8 25.9 26.8 34.0 17.0 16.0 23.6 16.6 19.9 8.3 72.7 41.5 36.0 29.3 33.0 37.4 26.5 52.3 23.1 26.4 34.3 16.6 19.8 22.0 24.4 32.0 50.2 13.1 59.1 33.7 51.7 4.4 12.9 19.0 48.5 11.8 29.4 18.8 21.2 21.8 24.5 16.4 31.2 22.9 6.7 70.5 34.6 34.3 40.0 24.2 25.0 27.8 58.6 30.5 25.4 38.4 25.6 24.1 0.0 1.0 0.8 0.8 0.4 0.8 0.6 0.7 0.8 0.5 0.7 0.2 0.9 2.1 0.5 0.6 1.0 0.0 0.9 23.0 22.2 21.5 24.6 22.9 19.7 24.7 20.9 19.4 16.8 22.9 23.0 21.2 16.0 21.8 9.8 30.0 18.7 15.9 13.2 38.7 22.3 26.8 19.3 9.3 11.5 11.0 7.3 33.3 10.2 38.1 36.3 5.9 11.0 82.2 33.4 25.1 18.2 16.8 4.6 9.5 14.7 9.3 15.8 29.0 32.2 19.0 21.5 19.2 9.4 14.0 43.7 8.7 21.5 10.2 15.8 22.0 109.9 17.1 25.8 10.6 7.5 20.1 14.7 15.5 7.5 14.5 21.1 26.3 16.1 13.3 22.2 33.5 8.9 24.4 25.7 0.0 19.0 17.7 69.1 23.9 37.8 24.3 33.0 28.8 22.2 19.3 27.9 FBXL22 "Fbl22, FLJ39626" ENSG00000197361 "F-box and leucine rich repeat protein 22" Q6P050 15 63597353-63602428 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 60.4;intestine: 60.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "MCF7: 4.9;SCLC-21H: 5.3;U-937: 3.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA047624, HPA054627" Uncertain Uncertain Nucleoli,Cytosol NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoli, Cytosol" "HPA047624: AB_2680107, HPA054627: AB_2682548" "unprognostic (2.17e-1)" "unprognostic (3.19e-2)" "unprognostic (2.99e-3)" "unprognostic (5.28e-2)" "unprognostic (3.03e-2)" "unprognostic (1.29e-2)" "unprognostic (1.15e-1)" "unprognostic (6.51e-2)" "unprognostic (2.53e-1)" "unprognostic (1.65e-1)" "unprognostic (2.82e-2)" "unprognostic (1.34e-1)" "unprognostic (1.07e-3)" "unprognostic (1.90e-2)" "unprognostic (1.99e-1)" "unprognostic (1.01e-2)" "unprognostic (1.02e-2)" 3.6 0.9 1.9 2.8 1.7 0.3 1.8 2.7 2.0 15.7 0.2 60.1 2.9 60.4 3.6 7.0 21.2 8.8 17.2 1.6 1.3 1.0 0.5 1.1 0.9 0.8 1.1 4.5 0.7 0.6 0.7 0.9 0.9 16.9 4.8 0.6 3.2 29.4 4.9 1.4 7.3 28.9 0.5 0.6 11.1 3.0 1.8 0.4 1.5 1.8 0.2 26.3 10.1 1.0 0.7 1.2 0.2 0.8 0.5 0.5 0.1 0.2 0.0 0.3 0.0 0.8 0.9 0.3 0.7 0.2 0.4 0.8 0.6 0.4 0.0 0.8 0.6 0.3 1.1 2.2 0.1 0.4 0.1 0.2 0.2 0.1 0.5 0.1 0.2 2.2 0.0 1.1 0.0 4.9 0.7 0.7 1.7 0.8 0.4 0.7 0.0 2.4 0.3 0.3 5.3 0.2 0.6 1.0 0.3 0.0 1.9 0.6 0.8 0.3 1.0 0.5 0.2 0.7 1.5 0.8 0.5 3.7 0.8 0.2 0.0 0.0 0.5 0.0 0.5 0.6 0.6 0.6 0.0 0.4 1.0 0.4 0.1 0.7 0.0 1.6 0.0 0.2 1.9 1.7 2.7 2.0 1.6 1.3 0.8 1.1 0.9 0.5 1.8 1.0 1.4 0.0 0.0 1.0 3.4 0.1 1.8 0.4 0.6 10.1 4.7 8.6 7.7 2.8 0.7 7.3 4.2 0.7 2.7 2.3 9.8 1.2 0.9 3.2 5.8 1.3 4.9 2.5 1.5 1.1 1.2 3.4 7.7 5.8 0.0 0.9 3.9 4.0 0.7 0.0 1.8 6.1 0.0 1.6 0.4 0.5 0.3 1.7 0.0 0.0 0.7 10.6 2.1 1.5 0.5 0.8 3.0 11.3 9.1 1.7 1.9 4.0 0.1 3.8 0.0 6.2 8.1 3.8 3.2 4.4 0.9 0.5 4.4 2.7 4.0 0.8 FBXO45 Fbx45 ENSG00000174013 "F-box protein 45" P0C2W1 3 196568611-196589059 "Predicted intracellular proteins" "Neurogenesis, Ubl conjugation pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040730 Uncertain Approved Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA040730: AB_10959311" "unprognostic (7.17e-3)" "unprognostic (1.14e-1)" "unprognostic (8.37e-2)" "unprognostic (1.01e-2)" "unprognostic (8.14e-2)" "unprognostic (2.89e-1)" "prognostic unfavorable (7.61e-5)" "prognostic unfavorable (3.77e-4)" "unprognostic (1.13e-2)" "unprognostic (9.48e-3)" "unprognostic (1.20e-3)" "prognostic unfavorable (1.16e-5)" "prognostic unfavorable (4.93e-5)" "unprognostic (5.18e-2)" "unprognostic (1.66e-1)" "unprognostic (6.93e-2)" "unprognostic (1.65e-1)" 5.1 4.2 10.7 6.1 11.5 13.9 7.3 11.8 14.8 4.5 6.8 6.9 5.3 4.7 3.0 8.9 3.6 4.4 3.6 11.0 10.9 3.7 6.9 4.5 6.7 10.7 10.9 5.0 4.6 7.2 3.1 5.4 10.4 5.1 7.0 8.2 4.0 4.3 13.8 12.7 5.1 5.0 11.6 5.1 5.5 12.2 11.5 8.8 3.7 11.5 10.0 6.8 5.0 11.7 45.5 8.5 17.6 22.4 11.6 11.4 20.9 19.7 9.0 15.3 15.6 23.9 15.1 19.1 33.1 12.8 22.8 19.0 33.9 22.5 28.1 27.7 15.3 34.8 15.5 15.1 11.1 46.9 17.1 5.8 24.9 17.3 31.8 8.0 16.9 30.5 42.4 39.2 17.2 45.3 27.5 21.9 27.4 40.3 32.5 23.1 23.0 46.2 12.9 18.3 35.6 24.4 21.4 36.8 23.5 15.4 63.3 31.1 16.8 17.7 19.1 25.7 53.8 38.3 68.5 52.6 15.4 59.6 17.3 1.3 0.9 1.1 0.8 0.9 1.4 0.5 0.8 0.5 1.2 0.8 0.8 0.9 0.4 0.6 1.1 1.4 1.6 0.4 10.7 11.5 11.8 14.8 11.0 10.9 10.7 10.9 10.4 11.6 11.5 11.7 10.2 12.8 4.1 6.5 6.6 9.8 10.2 5.6 4.6 20.1 10.5 7.7 10.8 4.3 4.2 3.7 14.6 2.6 11.5 7.9 0.0 4.4 15.5 8.0 12.9 8.0 17.4 6.1 13.8 7.7 4.6 7.8 10.7 8.8 1.3 6.9 7.9 9.9 5.8 13.5 15.0 8.2 4.1 9.1 11.0 18.9 5.6 7.6 5.4 8.4 8.3 9.3 4.1 6.6 12.4 8.3 4.8 6.4 8.0 14.8 4.0 3.4 6.8 10.7 0.0 10.5 7.5 32.4 24.4 9.4 13.5 1.9 8.2 7.1 9.8 14.5 FBXO5 "EMI1, FBX5, Fbxo31" ENSG00000112029 "F-box protein 5" Q9UKT4 6 152970519-152983579 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 44.1;lymphoid tissue: 27.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 36.0;Extravillous trophoblasts: 30.5;Spermatocytes: 32.3;Spermatogonia: 26.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB008106, HPA029048" Approved Supported Nucleoplasm NA Yes "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB008106: AB_828450, HPA029048: AB_10602132" "unprognostic (1.22e-2)" "unprognostic (7.21e-2)" "unprognostic (4.61e-3)" "unprognostic (1.24e-2)" "unprognostic (5.92e-2)" "unprognostic (2.94e-2)" "unprognostic (2.43e-8)" "unprognostic (2.46e-2)" "unprognostic (1.55e-2)" "unprognostic (7.32e-2)" "unprognostic (2.89e-1)" "unprognostic (5.86e-2)" "unprognostic (1.25e-9)" "prognostic favorable (8.65e-4)" "unprognostic (1.20e-1)" "unprognostic (1.72e-1)" "unprognostic (1.51e-1)" 3.1 3.1 1.5 7.3 1.6 44.1 4.5 2.6 2.1 4.0 1.9 5.0 4.6 5.3 4.5 3.7 3.0 2.6 1.8 1.4 1.7 3.1 4.4 3.4 14.9 1.6 1.6 4.1 3.0 2.3 2.1 6.3 1.7 3.0 5.1 3.3 2.7 2.9 0.9 4.3 4.3 5.0 1.6 5.5 4.6 3.9 1.8 27.3 4.4 2.6 14.6 4.0 3.0 2.0 33.7 17.2 70.8 48.1 5.3 10.8 22.6 79.9 35.5 58.7 65.6 35.6 19.8 81.6 23.9 21.3 39.7 31.4 56.4 26.7 70.0 44.2 50.6 82.3 24.1 38.7 10.2 74.4 48.6 7.7 4.9 39.8 30.9 14.3 27.3 42.3 88.2 74.5 53.9 25.7 85.2 47.6 41.5 25.8 25.0 71.0 56.8 52.8 20.8 18.0 46.1 47.9 56.6 30.2 15.6 24.7 21.8 68.7 20.6 43.9 57.4 51.1 94.8 24.9 29.5 120.4 31.9 54.3 54.2 0.0 1.9 0.0 2.8 2.5 4.0 5.1 4.7 5.2 3.7 5.0 4.6 4.8 0.0 7.1 3.2 4.3 6.6 2.5 1.5 1.6 2.6 2.1 1.4 1.7 1.6 1.6 1.7 1.6 1.8 2.0 6.0 0.0 1.1 1.3 9.8 9.9 3.7 4.0 7.4 3.2 5.7 5.2 1.8 2.8 3.9 1.8 6.2 15.2 13.5 2.6 3.9 3.0 0.4 2.3 10.5 5.7 4.8 36.0 1.0 1.6 30.5 9.1 7.7 4.0 2.5 16.6 5.0 1.9 7.9 1.7 0.9 6.1 2.0 3.2 6.1 0.1 4.4 5.3 1.8 1.9 4.2 4.1 9.2 1.5 2.1 1.5 0.5 6.0 24.7 3.6 1.5 3.6 1.9 3.6 13.1 8.6 8.9 32.3 26.1 10.2 5.3 5.9 7.9 8.0 6.3 2.0 FCGR3A "CD16, CD16a, FCG3, FCGR3" ENSG00000203747 "Fc fragment of IgG receptor IIIa" P08637 1 161541759-161550737 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 206.3;lymphoid tissue: 306.8" "Cell type enhanced" "Detected in many" "dendritic cells: 333.4;Hofbauer cells: 193.1;Kupffer cells: 807.9;Macrophages: 300.0;NK-cells: 579.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "intermediate monocyte: 1763.5;neutrophil: 1169.8;non-classical monocyte: 3948.7" "Group enriched" "Detected in all" 5 "granulocytes: 1169.8;monocytes: 3948.7" "Not detected" "Not detected" "CAB032435, HPA055431" Supported "Secreted to blood" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB032435: AB_626925, HPA055431: AB_2682815" "unprognostic (5.27e-2)" "unprognostic (9.95e-2)" "unprognostic (2.37e-2)" "unprognostic (1.66e-1)" "unprognostic (1.39e-1)" "unprognostic (1.82e-1)" "unprognostic (2.24e-2)" "unprognostic (6.06e-2)" "unprognostic (2.41e-1)" "unprognostic (1.64e-1)" "unprognostic (1.98e-2)" "unprognostic (7.52e-2)" "prognostic unfavorable (3.22e-6)" "unprognostic (1.14e-1)" "unprognostic (4.66e-2)" "unprognostic (1.03e-2)" "unprognostic (7.51e-2)" 52.9 41.9 18.4 99.8 20.4 27.3 14.7 19.3 27.2 8.2 26.5 12.5 5.8 5.9 5.9 4.9 9.1 24.5 22.3 16.9 22.0 7.9 111.5 206.3 37.1 37.7 27.9 6.6 7.8 13.6 11.3 71.0 30.6 6.9 12.6 6.9 14.7 7.6 3.3 2.2 5.7 68.4 31.7 306.8 6.8 7.7 28.8 9.3 7.0 4.3 3.9 32.5 3.5 39.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 6.5 26.2 9.6 513.6 1763.5 4.9 3.7 4.7 205.9 175.8 1.4 3.0 184.0 1169.8 136.2 3948.7 4.6 2.6 734.1 18.4 20.4 19.3 27.2 16.9 22.0 37.7 27.9 30.6 31.7 28.8 39.8 2.7 22.4 24.6 0.7 6.5 0.5 0.1 0.0 0.0 0.2 1.4 3.4 0.7 8.6 10.5 3.7 2.1 1.2 333.4 0.0 0.0 0.2 1.4 0.1 0.0 18.9 0.0 16.4 0.0 0.0 1.4 3.9 0.0 0.1 18.9 0.1 8.6 5.3 193.1 0.0 0.1 0.1 0.0 807.9 7.4 3.7 0.3 300.0 0.0 20.6 77.2 0.1 579.9 0.0 0.1 0.0 0.0 0.0 22.1 0.0 0.0 0.8 5.8 1.5 19.7 1.1 0.4 0.0 0.5 0.2 0.0 2.1 88.0 0.0 0.0 0.3 FCHO1 KIAA0290 ENSG00000130475 "FCH and mu domain containing endocytic adaptor 1" O14526 19 17747718-17788568 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 59.5;lymphoid tissue: 24.3;skin 1: 22.2" "Cell type enhanced" "Detected in many" "B-cells: 16.8;dendritic cells: 19.1;Oligodendrocytes: 46.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 62.4;RPMI-8226: 43.3;U-937: 38.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041653, HPA062981" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm Cytosol "HPA041653: AB_10795641, HPA062981: AB_2684915" "unprognostic (3.02e-1)" "unprognostic (9.52e-2)" "unprognostic (1.80e-1)" "unprognostic (4.54e-3)" "unprognostic (3.62e-2)" "unprognostic (5.63e-2)" "unprognostic (3.80e-2)" "unprognostic (1.23e-1)" "unprognostic (1.84e-1)" "unprognostic (2.16e-1)" "unprognostic (6.93e-2)" "unprognostic (5.48e-3)" "unprognostic (1.72e-9)" "unprognostic (3.76e-3)" "unprognostic (1.18e-1)" "unprognostic (2.21e-1)" "unprognostic (9.77e-3)" 2.2 1.8 24.9 14.7 33.7 20.2 1.5 21.7 32.6 1.0 8.6 2.5 3.2 1.3 1.4 1.1 1.5 4.2 0.8 24.1 25.6 1.4 2.2 3.7 24.3 27.5 28.6 1.7 0.7 1.1 3.9 1.1 29.7 1.0 2.2 3.4 1.3 0.8 0.6 22.2 8.1 1.7 19.9 15.5 3.4 4.4 29.2 17.6 1.0 0.8 17.4 3.0 1.0 59.5 0.9 11.9 7.5 5.2 0.2 0.2 7.5 1.1 0.3 0.3 0.5 1.5 1.4 62.4 17.1 0.5 1.4 2.3 3.7 2.3 0.2 27.6 2.1 4.9 1.4 6.4 0.6 15.7 10.2 0.1 0.3 0.0 0.4 0.4 1.6 30.2 24.9 28.9 0.0 17.4 36.2 27.8 3.6 14.7 28.7 30.2 0.2 43.3 0.2 1.2 1.3 2.5 0.3 5.9 0.9 0.9 6.0 15.4 1.3 0.1 4.1 0.9 0.4 18.2 9.0 33.4 0.9 38.5 0.5 13.2 9.6 10.1 7.0 14.3 6.0 12.4 7.9 6.3 14.5 12.3 7.4 6.1 37.8 6.4 11.5 15.3 7.6 7.4 24.9 33.7 21.7 32.6 24.1 25.6 27.5 28.6 29.7 19.9 29.2 59.5 0.4 0.0 1.5 0.7 16.8 0.0 0.4 0.2 0.6 7.8 2.0 4.3 0.9 2.8 0.4 1.8 0.0 2.9 19.1 2.0 0.0 0.5 1.5 0.8 0.2 2.4 1.2 2.5 15.0 0.0 4.6 2.5 1.5 1.0 9.5 2.9 2.5 0.0 6.8 0.0 13.0 1.7 0.0 8.7 14.3 0.7 2.5 11.0 1.8 6.5 12.3 0.1 13.4 3.0 46.9 2.1 0.5 8.6 4.5 0.3 0.1 0.1 0.7 0.8 0.0 0.2 0.6 0.9 5.5 0.2 0.6 0.8 9.8 12.2 1.8 0.3 FCRL5 "BXMAS1, CD307e, FCRH5, IRTA2" ENSG00000143297 "Fc receptor like 5" Q96RD9 1 157513377-157552515 "CD markers, Disease related genes, Predicted membrane proteins, Predicted secreted proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "lymphoid tissue: 36.3" "Group enriched" "Detected in some" 5 "B-cells: 102.6;Early spermatids: 63.6;Plasma cells: 190.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "memory B-cell: 13.0;naive B-cell: 14.2" "Lineage enriched" "Detected in single" 17 "B-cells: 14.2" "Group enriched" "Detected in some" 5 "U-266/70: 3.4;U-698: 7.4" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 169000000 65000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.30e-3)" "unprognostic (3.51e-2)" "unprognostic (7.59e-3)" "unprognostic (1.57e-2)" "unprognostic (9.41e-3)" "unprognostic (4.32e-5)" "unprognostic (2.61e-2)" "unprognostic (6.93e-2)" "unprognostic (7.40e-2)" "unprognostic (7.66e-3)" "unprognostic (4.01e-1)" "unprognostic (1.39e-1)" "unprognostic (9.51e-10)" "unprognostic (1.20e-1)" "unprognostic (4.40e-1)" "unprognostic (8.99e-2)" "unprognostic (2.78e-1)" 0.4 0.4 0.0 13.8 0.0 2.3 2.4 0.0 0.1 0.6 0.0 5.5 5.8 0.1 0.3 0.8 0.4 1.2 0.3 0.0 0.0 0.4 0.3 1.1 24.4 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.2 4.4 0.0 3.8 0.3 0.0 0.0 5.0 0.1 0.1 15.1 4.5 0.6 0.0 4.1 0.6 0.0 36.3 4.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.0 0.0 0.0 0.0 14.2 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.5 0.3 102.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 3.1 2.9 0.1 0.0 0.0 63.6 0.0 0.0 0.1 0.0 1.3 0.1 0.0 0.2 0.3 1.1 0.0 1.3 0.0 0.4 1.8 0.3 0.0 0.1 0.0 0.0 0.3 0.3 10.1 0.3 0.2 23.2 0.0 0.5 0.0 0.0 0.5 0.2 0.0 0.0 0.0 190.5 0.2 0.0 0.1 0.0 0.0 6.6 0.0 0.3 1.2 0.1 0.1 0.0 0.7 5.7 0.0 0.6 0.0 FDPS ENSG00000160752 "Farnesyl diphosphate synthase" P14324 1 155308748-155320666 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Host-virus interaction, Isoprene biosynthesis, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Transferase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 355.7" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 927.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HBEC3-KT: 1187.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028200 Approved Approved Nucleoplasm,Cytosol NA NA 1500000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 37: Intestine - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol Nucleoplasm "HPA028200: AB_10612109" "unprognostic (1.23e-1)" "unprognostic (8.46e-3)" "unprognostic (2.47e-2)" "unprognostic (6.57e-2)" "unprognostic (4.58e-2)" "unprognostic (2.84e-2)" "prognostic unfavorable (7.35e-4)" "unprognostic (4.21e-2)" "unprognostic (6.78e-3)" "unprognostic (1.64e-3)" "unprognostic (7.19e-2)" "unprognostic (2.25e-2)" "unprognostic (1.11e-2)" "unprognostic (8.25e-2)" "unprognostic (2.07e-1)" "unprognostic (5.65e-2)" "unprognostic (8.44e-2)" 73.5 188.2 48.2 66.5 50.4 69.5 68.8 60.1 58.8 63.4 51.1 88.7 167.2 57.5 73.0 142.5 57.4 39.8 72.2 49.9 64.6 78.0 355.7 86.1 76.1 71.1 62.5 45.0 75.7 67.9 40.4 72.5 77.5 56.1 102.9 45.9 82.6 42.7 60.9 107.1 81.1 66.0 53.6 59.3 81.5 42.0 55.0 72.6 46.8 66.7 102.3 47.0 76.8 55.0 293.9 156.2 561.5 204.4 128.7 467.7 199.6 136.8 268.1 213.6 344.2 255.4 677.7 222.3 323.6 120.6 506.9 319.1 338.9 1187.5 198.9 122.4 242.5 129.4 260.1 311.5 210.8 212.1 142.0 335.5 184.6 339.6 168.8 96.4 377.6 322.3 235.1 579.9 225.3 315.1 273.6 205.0 338.9 216.4 225.5 231.6 243.2 620.0 567.7 193.0 217.4 185.6 140.7 253.0 243.0 317.3 182.6 567.6 277.1 118.4 144.3 74.3 254.9 244.3 202.3 401.1 115.3 221.7 191.1 90.6 85.5 124.1 89.2 92.9 79.7 102.8 77.8 91.1 95.6 95.1 69.9 87.1 38.9 115.2 70.0 76.2 113.7 134.7 48.2 50.4 60.1 58.8 49.9 64.6 71.1 62.5 77.5 53.6 55.0 55.0 154.2 73.7 181.6 38.5 68.4 36.8 83.3 927.7 42.1 69.4 84.6 56.9 1.8 97.2 431.5 53.3 62.6 207.8 74.9 343.0 137.0 180.9 216.6 56.7 38.2 161.9 71.4 133.4 30.8 329.9 198.7 59.8 52.0 77.8 62.8 116.6 168.1 361.9 112.0 55.5 28.1 135.7 299.1 54.8 44.4 67.9 60.9 52.8 96.0 15.0 144.7 81.1 87.6 22.6 39.7 256.7 324.3 70.3 91.3 206.1 194.1 145.0 129.6 90.8 72.3 47.0 177.5 42.0 14.2 49.7 59.8 143.5 68.3 230.6 165.4 148.2 FITM2 "C20orf142, dJ881L22.2, FIT2" ENSG00000197296 "Fat storage inducing transmembrane protein 2" Q8N6M3 20 44302840-44311202 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid metabolism" Hydrolase "Deafness, Disease variant, Dystonia, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "heart muscle: 67.4" "Cell type enriched" "Detected in many" 9 "Cardiomyocytes: 153.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (2.92e-2)" "unprognostic (7.61e-2)" "unprognostic (2.27e-2)" "unprognostic (2.10e-3)" "unprognostic (1.02e-1)" "unprognostic (3.57e-3)" "unprognostic (1.63e-2)" "unprognostic (3.90e-2)" "unprognostic (8.43e-2)" "unprognostic (5.19e-2)" "unprognostic (6.56e-3)" "unprognostic (1.19e-1)" "prognostic favorable (8.98e-12)" "unprognostic (2.07e-1)" "unprognostic (2.54e-1)" "unprognostic (3.38e-3)" "unprognostic (2.49e-3)" 11.4 11.1 4.8 2.9 5.0 1.2 7.0 5.7 6.3 4.2 5.9 5.2 4.3 4.0 8.7 3.3 3.7 3.2 67.4 4.8 5.9 7.9 6.4 4.1 2.2 6.9 5.9 4.6 7.4 13.6 5.2 1.9 7.4 6.4 6.0 6.7 6.5 4.4 9.2 5.7 3.9 5.3 4.2 2.6 4.6 3.8 5.4 1.7 6.3 16.8 2.6 4.5 3.1 4.7 7.2 10.9 4.5 6.6 31.4 12.8 4.6 11.5 8.4 8.9 4.9 13.5 5.1 4.9 6.5 13.0 14.3 15.8 5.7 7.7 9.6 1.4 2.7 1.6 6.5 22.9 6.6 3.1 4.0 9.7 17.2 6.2 4.7 4.9 6.4 3.1 2.7 14.2 9.1 22.4 1.2 3.4 1.1 10.8 13.9 1.9 8.4 4.9 5.1 6.7 2.7 3.2 24.4 13.5 10.3 2.0 16.5 2.4 7.9 28.2 12.6 16.6 6.8 5.2 14.4 1.3 12.6 4.9 14.4 0.7 1.0 0.6 1.1 1.0 1.2 0.6 1.2 0.9 1.0 0.6 2.0 1.6 0.4 1.4 0.8 0.6 1.2 0.9 4.8 5.0 5.7 6.3 4.8 5.9 6.9 5.9 7.4 4.2 5.4 4.7 2.8 6.4 9.7 1.3 3.6 6.9 3.5 2.8 1.2 6.4 5.0 3.4 153.9 11.5 4.3 5.5 6.2 2.0 1.0 5.1 1.9 5.2 4.6 2.2 5.0 4.4 9.1 0.8 2.3 8.6 3.5 9.4 4.1 2.1 0.0 4.4 8.2 14.1 3.4 6.7 2.1 4.8 0.0 3.8 2.2 1.2 7.8 1.7 7.2 1.0 2.3 6.6 2.1 4.0 0.9 5.7 4.1 7.5 3.1 3.1 5.9 6.2 4.0 5.9 0.0 5.6 6.3 9.1 6.0 2.7 8.1 1.5 2.1 16.3 9.2 2.2 FLG ENSG00000143631 Filaggrin P20930 1 152302165-152325239 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Developmental protein" "Cancer-related genes, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 29 "skin 1: 458.2" "Cell type enriched" "Detected in some" 13 "Suprabasal keratinocytes: 44.0" "Cancer enriched" "Detected in some" 7 "melanoma: 11.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 10.1;NTERA-2: 3.1;TIME: 2.1;U-2 OS: 2.4;U-2197: 2.6;WM-115: 2.0" "Not detected" "Not detected" "CAB002210, HPA027505, HPA030188, HPA030189" Enhanced Enhanced "Cytoplasmic bodies" NA NA 3800000 "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "Cytoplasmic bodies" "CAB002210: AB_563731, HPA027505: AB_10600107, HPA030188: AB_10601749, HPA030189: AB_10601999" "unprognostic (3.37e-2)" "unprognostic (3.76e-1)" "unprognostic (8.83e-2)" "unprognostic (2.96e-3)" "unprognostic (9.65e-2)" "unprognostic (1.17e-1)" "unprognostic (2.02e-1)" "unprognostic (4.03e-2)" "unprognostic (1.12e-1)" "unprognostic (9.98e-2)" "unprognostic (1.73e-1)" "unprognostic (2.40e-1)" "unprognostic (2.35e-2)" "unprognostic (1.45e-1)" "unprognostic (4.28e-2)" "unprognostic (4.15e-2)" "unprognostic (7.41e-3)" 0.3 0.4 0.7 0.1 0.3 0.1 15.7 0.3 0.4 6.5 0.0 0.2 0.0 0.5 0.0 12.0 0.4 0.1 0.4 0.3 1.4 0.4 0.2 0.2 0.0 1.6 0.9 0.9 0.4 0.0 0.2 0.0 1.2 0.2 0.0 0.2 2.7 0.0 1.8 458.2 0.1 0.0 0.8 0.1 0.2 0.3 0.8 0.5 0.3 0.0 0.5 0.1 4.9 0.6 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.5 0.0 10.1 0.0 0.0 0.0 1.1 0.0 0.8 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.1 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 2.1 0.8 2.4 2.6 1.9 0.0 0.0 0.0 0.1 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.3 0.3 0.4 0.3 1.4 1.6 0.9 1.2 0.8 0.8 0.6 0.0 0.0 0.0 0.0 0.0 3.2 0.0 1.0 0.0 0.6 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 1.0 44.0 0.0 0.1 0.1 0.0 0.0 FLNC "ABP-280, ABPL, FLN2" ENSG00000128591 "Filamin C" Q14315 7 128830406-128859274 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" Actin-binding "Cardiomyopathy, Disease variant, Myofibrillar myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 635.2;skeletal muscle: 1384.8;tongue: 442.6" "Cell type enriched" "Detected in many" 26 "Cardiomyocytes: 1892.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 393.6;fHDF/TERT166: 180.2;hTEC/SVTERT24-B: 190.6;U-2 OS: 163.5" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA006135, HPA071007" Enhanced Supported "Plasma membrane,Cytosol" NA NA 26000000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane, Cytosol" "HPA006135: AB_1848602, HPA071007: " "unprognostic (1.25e-1)" "unprognostic (7.38e-2)" "unprognostic (4.47e-2)" "unprognostic (1.40e-2)" "prognostic unfavorable (2.80e-4)" "unprognostic (1.64e-3)" "unprognostic (4.42e-3)" "prognostic unfavorable (2.17e-5)" "unprognostic (1.03e-3)" "unprognostic (2.35e-2)" "unprognostic (1.35e-3)" "unprognostic (6.37e-2)" "prognostic unfavorable (5.69e-4)" "unprognostic (5.68e-3)" "unprognostic (1.15e-1)" "unprognostic (1.52e-3)" "prognostic unfavorable (3.73e-5)" 13.1 3.4 5.8 25.9 11.5 0.0 5.9 11.5 9.9 16.9 3.0 215.4 9.4 96.6 4.6 40.3 35.4 13.8 635.2 5.9 16.7 2.8 1.1 12.5 0.6 52.1 11.1 9.4 2.1 3.2 1.6 2.4 29.9 71.1 9.8 0.5 16.5 100.7 1384.8 8.9 40.3 114.4 51.7 0.7 65.6 2.2 19.1 0.3 4.3 442.6 0.2 162.7 21.3 49.8 0.1 0.8 4.2 0.1 34.4 41.2 4.1 393.6 73.6 109.2 52.3 124.0 1.0 0.1 64.7 180.2 44.9 0.1 23.7 0.9 64.4 0.2 13.1 0.1 20.2 0.1 43.2 0.0 0.2 78.0 0.1 190.6 0.1 44.2 69.0 0.3 49.0 0.2 75.8 0.0 0.0 1.5 64.5 0.1 22.6 0.1 127.5 1.0 0.1 0.0 2.1 7.0 0.7 0.1 0.3 88.0 0.4 1.6 144.6 38.2 163.5 10.1 0.2 0.1 0.0 0.3 129.0 0.1 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 11.5 11.5 9.9 5.9 16.7 52.1 11.1 29.9 51.7 19.1 49.8 3.6 3.2 0.5 0.7 0.0 3.7 0.3 0.1 1.2 0.6 0.3 1.3 1892.3 0.0 1.9 1.8 0.0 0.4 0.2 0.5 0.0 0.7 0.4 1.8 5.0 31.4 0.0 0.0 0.2 0.2 3.0 31.6 0.0 2.9 0.0 0.6 1.8 0.0 0.9 0.0 1.1 0.3 0.0 0.0 6.9 0.9 5.3 0.5 5.4 0.0 0.0 0.1 0.0 0.0 5.8 2.6 0.1 10.5 1.2 2.7 0.0 1.1 0.0 0.2 0.0 71.8 38.1 0.3 1.0 0.2 4.5 1.9 1.0 0.1 0.2 1.0 FLT1 "FLT, VEGFR1" ENSG00000102755 "Fms related receptor tyrosine kinase 1" P17948 13 28300346-28495145 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Chemotaxis, Differentiation" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "placenta: 432.4" "Cell type enhanced" "Detected in many" "Adipocytes: 411.6;Endothelial cells: 263.1;Extravillous trophoblasts: 815.4;Hepatic stellate cells: 234.9;Microglial cells: 433.8;Syncytiotrophoblasts: 1127.1" "Cancer enhanced" "Detected in all" "renal cancer: 28.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 71.8;BJ hTERT+: 57.2;HMC-1: 349.2;HUVEC TERT2: 64.9;WM-115: 127.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011740, HPA014290, CAB068189, CAB068190" Enhanced Supported "Plasma membrane,Actin filaments" "Secreted to blood" NA NA 876000 87000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 3: HMC-1 - Innate immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane" "Actin filaments" "CAB068189: AB_2665636, CAB068190: AB_2665637, HPA011740: AB_1858737, HPA014290: AB_1858738" "unprognostic (3.33e-2)" "unprognostic (3.52e-3)" "unprognostic (1.13e-3)" "unprognostic (5.02e-2)" "unprognostic (3.65e-1)" "unprognostic (5.03e-2)" "unprognostic (8.25e-2)" "unprognostic (2.27e-3)" "unprognostic (9.91e-2)" "unprognostic (6.61e-2)" "unprognostic (2.33e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (2.19e-4)" "unprognostic (4.20e-2)" "unprognostic (6.00e-2)" "unprognostic (1.57e-1)" "unprognostic (6.32e-2)" 47.6 9.6 37.6 9.1 36.2 1.1 31.2 37.0 43.0 16.4 24.6 9.4 7.5 17.2 3.7 5.9 11.7 16.6 46.0 33.3 39.8 34.9 18.2 25.8 5.3 44.6 40.0 4.4 12.7 30.5 9.0 432.4 50.1 13.9 6.1 52.5 7.0 11.0 19.9 5.9 9.3 17.4 33.4 18.6 10.9 17.4 59.6 3.6 48.9 38.8 5.7 14.0 9.5 38.7 0.1 0.0 0.0 0.6 0.6 0.9 0.3 71.8 57.2 25.8 14.9 0.0 0.2 0.1 0.1 9.6 0.0 0.3 6.7 0.0 45.4 0.0 2.0 0.2 0.1 0.0 0.1 0.0 349.2 0.6 0.0 0.1 1.0 0.1 64.9 6.1 1.7 0.3 0.0 0.3 4.5 3.7 37.5 0.0 0.1 2.9 0.0 0.1 0.1 0.1 8.1 0.6 0.0 0.1 0.2 44.4 0.3 0.2 6.3 0.2 1.2 0.1 0.1 2.1 1.0 0.2 0.4 0.3 127.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 0.1 0.1 0.5 0.0 0.0 0.1 0.0 0.0 37.6 36.2 37.0 43.0 33.3 39.8 44.6 40.0 50.1 33.4 59.6 38.7 411.6 0.0 6.0 2.0 4.7 4.1 0.7 0.2 3.4 17.8 1.2 1.5 26.5 2.8 2.9 0.0 4.2 197.2 1.4 0.1 1.9 0.6 157.2 0.5 1.5 263.1 0.0 0.0 0.9 0.0 815.4 32.1 0.5 2.1 1.3 0.1 234.9 6.9 30.8 1.7 14.5 0.0 0.0 12.5 23.6 173.8 18.6 15.3 0.0 433.8 0.0 153.2 0.0 9.5 2.0 0.0 0.0 48.5 4.1 1.3 0.0 0.1 1.8 9.7 92.1 11.4 30.1 14.6 4.6 1.0 4.8 1127.1 2.8 1.5 0.0 1.1 FMO5 ENSG00000131781 "Flavin containing dimethylaniline monoxygenase 5" P49326 1 147175351-147243050 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 683.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 64.2;Cholangiocytes: 133.0;Hepatocytes: 265.4;Proximal enterocytes: 108.8;Proximal tubular cells: 69.2" "Cancer enriched" "Detected in many" 7 "liver cancer: 43.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 4 "Hep G2: 41.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012373 Enhanced Supported "Endoplasmic reticulum,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Endoplasmic reticulum, Cytosol" "HPA012373: AB_1848975" "unprognostic (2.70e-1)" "unprognostic (1.28e-1)" "unprognostic (1.33e-1)" "unprognostic (2.06e-2)" "unprognostic (1.39e-1)" "unprognostic (3.96e-2)" "unprognostic (2.43e-2)" "unprognostic (2.94e-2)" "unprognostic (1.10e-1)" "unprognostic (1.85e-2)" "unprognostic (2.93e-1)" "unprognostic (1.13e-1)" "prognostic favorable (1.34e-6)" "unprognostic (3.77e-1)" "unprognostic (1.38e-1)" "unprognostic (1.85e-1)" "unprognostic (4.11e-2)" 3.1 5.7 2.0 5.1 2.9 2.0 46.1 3.9 2.8 7.8 0.5 41.3 71.3 2.8 6.9 1.2 3.6 15.8 3.1 2.1 2.4 51.5 683.3 27.1 4.0 4.2 2.9 4.1 48.1 68.3 6.7 2.4 4.8 9.7 46.6 0.9 32.7 4.0 0.8 11.6 73.9 3.5 3.2 4.0 120.1 5.2 3.1 1.1 2.0 1.4 2.5 3.9 1.5 5.6 0.1 1.1 0.6 0.1 2.8 0.8 0.9 0.7 0.5 0.3 0.8 0.7 2.4 0.4 0.8 0.8 0.2 0.4 0.0 0.0 0.0 1.4 0.2 1.6 0.1 41.7 0.9 1.4 9.0 1.3 0.2 0.4 0.0 0.4 0.6 0.2 0.1 0.1 1.5 1.4 0.2 0.7 2.8 5.3 0.8 0.4 0.5 0.4 3.4 0.6 0.5 0.3 0.9 2.8 1.3 1.3 2.1 10.4 1.1 0.0 0.3 0.9 0.0 0.3 0.0 0.3 1.1 0.5 0.3 7.0 12.9 4.1 2.0 5.9 0.3 4.7 0.5 0.6 5.4 8.5 0.3 1.3 1.3 1.2 1.8 2.5 1.6 3.9 2.0 2.9 3.9 2.8 2.1 2.4 4.2 2.9 4.8 3.2 3.1 5.6 2.8 9.6 64.2 11.1 6.4 1.7 3.9 0.9 1.8 2.0 17.5 6.7 1.9 133.0 10.4 14.7 0.0 1.5 1.7 60.8 7.9 7.5 7.7 2.5 1.8 2.7 6.7 4.8 8.2 5.9 1.1 2.9 24.5 6.1 5.7 9.8 5.0 265.4 4.0 3.3 6.4 34.4 4.1 10.0 2.3 4.5 2.8 4.6 28.4 10.3 5.3 0.2 4.1 10.1 17.5 7.0 29.0 1.5 0.4 5.6 108.8 69.2 18.1 1.3 0.0 2.2 1.0 5.9 0.9 1.3 1.6 1.4 2.6 6.6 20.7 6.4 FNDC1 "bA243O10.1, dJ322A24.1, FNDC2, KIAA1866" ENSG00000164694 "Fibronectin type III domain containing 1" Q4ZHG4 6 159169400-159272108 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 14.2;thyroid gland: 20.3" "Group enriched" "Detected in some" 4 "Fibroblasts: 28.7;Smooth muscle cells: 11.5" "Cancer enhanced" "Detected in many" "thyroid cancer: 32.5" "Group enriched" "Detected in many" 6 "cerebral cortex: 5.4;hippocampal formation: 8.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 1.0;fHDF/TERT166: 2.9;SuSa: 3.1" "Region enhanced" "Detected in many" "olfactory bulb: 7.0" "Region enhanced" "Detected in many" "spinal cord: 10.3" "HPA030962, HPA030963" Approved Approved "Nuclear speckles" "Secreted to extracellular matrix" NA NA 14000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Nuclear speckles" "HPA030962: AB_10696212, HPA030963: AB_2673676" "unprognostic (4.59e-2)" "unprognostic (9.17e-3)" "unprognostic (7.62e-2)" "prognostic favorable (6.10e-5)" "unprognostic (4.57e-1)" "unprognostic (2.11e-1)" "unprognostic (5.52e-2)" "unprognostic (1.18e-1)" "unprognostic (1.30e-1)" "unprognostic (1.08e-1)" "unprognostic (4.18e-2)" "unprognostic (1.74e-1)" "prognostic unfavorable (1.93e-6)" "unprognostic (6.49e-3)" "unprognostic (1.12e-1)" "unprognostic (3.10e-1)" "unprognostic (1.76e-3)" 5.4 0.5 0.5 1.9 0.3 0.0 2.1 0.1 5.4 6.5 0.2 12.9 2.5 2.2 0.0 1.1 0.6 14.2 3.9 8.7 0.3 0.6 0.7 1.6 2.8 0.1 1.0 1.2 1.1 0.3 0.2 0.9 0.0 0.4 1.8 0.1 0.9 0.8 2.1 0.9 4.2 11.7 0.3 0.5 0.4 0.4 0.4 0.1 20.3 9.6 2.4 1.0 1.6 1.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 1.0 2.9 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 3.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.1 5.4 8.7 0.3 0.1 1.0 0.0 0.3 0.4 1.2 2.6 0.0 0.6 0.0 0.0 3.2 0.0 0.0 0.0 0.3 0.1 0.5 2.1 0.0 0.6 0.0 0.0 0.1 0.0 0.0 1.9 0.0 0.3 0.4 4.7 0.7 0.0 0.0 0.2 0.0 0.2 28.7 0.0 0.3 0.0 0.1 1.4 0.0 0.2 0.0 1.7 0.0 0.0 0.0 3.1 0.0 0.3 0.2 1.8 2.8 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 3.0 11.5 1.1 1.4 0.0 1.4 0.1 0.5 0.1 0.0 0.0 FNTB FPTB ENSG00000257365 "Farnesyltransferase, CAAX box, beta" P49356 14 64986895-65062652 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Prenyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 70.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA062743 Uncertain Approved Centrosome NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 17: WM-115 - Nervous system development" "Cluster 51: Myeloid cells - Hemostasis" Centrosome "HPA062743: AB_2684861" "unprognostic (2.79e-1)" "unprognostic (1.50e-2)" "unprognostic (1.54e-1)" "unprognostic (8.57e-3)" "unprognostic (1.88e-1)" "unprognostic (6.88e-2)" "prognostic unfavorable (6.03e-4)" "unprognostic (6.21e-2)" "unprognostic (3.11e-2)" "unprognostic (1.46e-2)" "unprognostic (1.70e-2)" "unprognostic (2.11e-1)" "unprognostic (2.49e-3)" "unprognostic (2.36e-2)" "unprognostic (3.60e-1)" "unprognostic (5.56e-2)" "unprognostic (1.11e-3)" 8.7 8.7 15.9 5.1 30.2 2.9 7.8 40.7 20.1 7.7 13.5 6.5 5.9 6.6 8.4 13.3 9.5 5.9 12.9 14.5 20.7 8.2 5.8 6.7 5.7 55.0 34.2 7.3 5.6 13.0 7.0 8.7 46.5 9.1 7.7 6.1 9.2 9.3 18.1 11.8 5.2 11.6 36.7 4.7 5.5 9.5 30.7 6.5 5.8 19.7 8.3 7.6 8.9 70.0 37.1 31.9 20.4 12.5 13.9 11.9 14.6 20.2 14.7 22.4 23.0 15.9 14.6 6.0 12.0 21.1 13.2 24.1 47.5 15.1 18.3 9.0 15.9 23.2 8.0 28.1 9.0 8.3 32.2 9.7 14.3 9.4 5.7 22.4 19.1 10.9 13.7 8.4 13.1 30.9 13.3 22.6 8.4 23.1 29.9 12.2 17.6 7.6 16.2 15.7 12.0 13.5 11.9 24.4 30.2 15.9 22.7 14.0 15.2 16.2 34.7 8.4 14.2 5.7 5.6 6.6 18.3 10.3 39.4 21.9 12.8 11.5 3.8 9.9 9.6 2.5 6.2 5.1 7.4 1.7 4.7 3.7 3.4 4.0 5.1 5.8 6.2 7.4 15.9 30.2 40.7 20.1 14.5 20.7 55.0 34.2 46.5 36.7 30.7 70.0 3.9 12.8 2.2 0.0 1.6 2.4 3.5 4.3 2.8 4.6 6.2 6.6 8.3 2.8 5.6 3.7 2.1 15.9 2.4 4.3 0.0 6.6 9.2 3.9 3.0 4.5 7.7 7.8 0.0 4.8 15.3 4.9 4.1 4.8 0.0 12.7 5.0 8.0 8.1 5.0 0.0 5.9 6.1 8.1 2.5 6.0 5.6 15.7 5.4 0.0 7.5 7.6 2.1 0.0 0.0 4.2 1.9 8.6 2.1 4.7 4.0 6.0 4.0 4.1 19.7 5.1 5.5 2.7 4.7 6.7 3.7 8.2 2.5 7.3 5.3 3.3 FOLR1 "FOLR, FRα" ENSG00000110195 "Folate receptor alpha" P15328 11 72189558-72196323 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters" Transport Receptor Neurodegeneration "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 480.2;fallopian tube: 187.2;lung: 193.5;salivary gland: 219.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 496.8;Alveolar cells type 2: 213.3;Breast glandular cells: 211.3;Club cells: 276.3;Collecting duct cells: 318.2;Cytotrophoblasts: 462.2;Proximal tubular cells: 366.0;Syncytiotrophoblasts: 259.0" "Cancer enhanced" "Detected in many" "ovarian cancer: 259.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "HeLa: 444.2;RPTEC TERT1: 476.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA077030 Approved "Nuclear membrane" "Secreted to blood" NA NA 448000 140000 "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 30: Mammary glandular cells - Lactation" "Nuclear membrane" "HPA077030: " "unprognostic (3.30e-1)" "unprognostic (2.19e-1)" "unprognostic (6.55e-2)" "unprognostic (3.49e-2)" "unprognostic (7.67e-3)" "unprognostic (1.98e-2)" "prognostic unfavorable (2.50e-4)" "unprognostic (1.18e-2)" "unprognostic (8.13e-2)" "unprognostic (2.47e-2)" "unprognostic (2.58e-2)" "unprognostic (2.87e-3)" "unprognostic (1.67e-1)" "unprognostic (2.52e-1)" "unprognostic (1.11e-1)" "unprognostic (2.20e-1)" "unprognostic (2.69e-1)" 0.1 1.7 2.7 0.2 1.8 0.1 28.3 11.8 1.8 123.5 480.2 0.5 0.3 1.9 7.6 3.4 187.2 2.4 0.6 14.1 4.1 153.0 0.2 193.5 0.0 5.7 7.8 0.7 7.1 17.5 8.1 36.2 3.8 1.5 0.4 0.5 219.5 15.2 0.1 2.5 0.4 0.2 3.2 0.2 33.0 0.2 7.7 0.2 45.9 0.0 0.4 0.1 0.1 2.7 0.2 0.2 0.0 0.2 0.0 0.0 64.7 0.1 0.1 0.1 0.1 44.5 46.0 0.0 45.5 0.8 0.0 0.9 2.4 2.1 0.2 0.1 1.4 1.0 444.2 1.3 0.0 0.0 0.1 1.8 0.1 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.3 0.5 0.1 0.1 2.2 0.7 0.0 0.5 15.1 0.0 476.5 0.0 0.1 3.0 1.4 7.1 0.1 38.5 65.7 0.5 0.0 0.0 8.4 0.3 0.0 0.2 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 1.8 11.8 1.8 14.1 4.1 5.7 7.8 3.8 3.2 7.7 2.7 1.0 496.8 213.3 0.0 1.3 0.9 7.9 80.3 0.0 0.0 211.3 62.9 0.2 34.3 276.3 318.2 0.0 462.2 1.1 0.0 133.1 14.3 0.1 33.6 2.3 3.4 1.8 0.0 0.0 1.4 110.9 4.3 9.7 33.7 5.1 0.0 0.0 0.0 29.5 0.0 0.0 0.1 87.5 0.0 0.4 0.0 0.6 3.8 0.0 0.0 0.0 2.2 0.0 0.0 0.0 6.7 0.0 0.0 0.0 6.3 0.0 366.0 149.1 0.1 0.0 0.1 6.3 0.0 0.5 3.2 0.1 259.0 2.2 0.3 0.3 10.4 FOXI1 "FKHL10, FREAC6" ENSG00000168269 "Forkhead box I1" Q12951 5 170105897-170109734 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 44.0;salivary gland: 11.4" "Cell type enriched" "Detected in some" 4 "Ionocytes: 132.2" "Group enriched" "Detected in many" 7 "breast cancer: 5.8;renal cancer: 23.1" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 16 "eosinophil: 1.5" "Lineage enriched" "Detected in single" 16 "granulocytes: 1.5" "Group enriched" "Detected in some" 5 "MCF7: 1.4;SuSa: 2.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA071469 Enhanced Supported Nucleoli,Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 12: NES - Nervous system development" "Cluster 39: Non-specific - Basic cellular processes" Nucleoli Vesicles "HPA071469: AB_2686403" "unprognostic (3.06e-1)" "unprognostic (1.24e-1)" "unprognostic (2.09e-1)" "unprognostic (2.48e-2)" "unprognostic (8.06e-2)" "unprognostic (7.47e-2)" "unprognostic (2.73e-1)" "unprognostic (1.52e-2)" "unprognostic (9.71e-3)" "unprognostic (4.88e-3)" "unprognostic (6.20e-2)" "unprognostic (1.34e-2)" "unprognostic (2.22e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 44.0 0.0 0.0 0.0 0.6 0.0 0.0 0.3 0.5 0.1 0.0 0.1 3.0 0.0 0.0 11.4 1.5 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 1.5 0.2 0.0 0.0 7.6 6.5 0.3 0.0 0.3 1.8 0.0 0.0 0.1 0.0 27.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 132.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 1.0 0.2 0.0 0.0 0.0 FOXK2 "ILF, ILF1" ENSG00000141568 "Forkhead box K2" Q01167 17 82519713-82644662 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027523, HPA073491" Approved Supported Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 10: Basophils - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm "Vesicles, Mitochondria" "HPA027523: AB_10601013, HPA073491: " "unprognostic (2.39e-1)" "unprognostic (8.28e-2)" "unprognostic (2.05e-1)" "unprognostic (9.52e-2)" "unprognostic (3.11e-1)" "unprognostic (1.43e-1)" "prognostic unfavorable (1.24e-6)" "unprognostic (3.35e-2)" "unprognostic (2.25e-1)" "unprognostic (5.19e-2)" "unprognostic (2.18e-2)" "unprognostic (2.26e-1)" "unprognostic (3.80e-3)" "unprognostic (2.24e-2)" "unprognostic (4.89e-2)" "unprognostic (1.12e-1)" "unprognostic (1.52e-2)" 14.0 24.0 10.7 12.6 13.2 8.0 12.1 14.7 16.3 14.2 1.2 18.1 9.3 19.7 9.8 20.2 13.2 10.0 17.1 12.4 10.5 12.7 13.1 14.2 12.5 5.8 7.1 14.7 15.4 20.0 17.7 15.7 6.3 13.3 9.4 11.6 12.1 12.5 43.0 18.8 12.1 16.4 3.0 11.6 14.7 28.1 9.4 18.4 15.4 28.4 11.9 15.5 13.4 12.7 48.4 50.4 46.3 50.9 26.2 28.5 31.0 27.6 31.6 47.4 47.9 49.1 30.1 40.7 19.6 34.4 52.3 27.6 49.7 32.0 44.4 28.3 47.9 42.3 32.7 49.4 41.0 47.3 27.2 27.2 57.2 50.4 56.8 29.2 48.9 43.7 57.7 40.7 26.3 28.8 81.8 30.4 26.5 39.7 38.2 53.0 39.4 34.2 21.7 40.1 76.2 56.1 27.4 69.0 65.1 48.8 48.7 54.3 38.3 62.2 43.2 42.2 56.6 46.7 45.1 53.5 33.4 39.0 33.4 1.5 1.0 1.2 1.4 0.7 1.1 1.5 1.1 1.4 1.2 1.0 0.8 0.9 0.1 1.6 0.9 2.0 1.3 0.6 10.7 13.2 14.7 16.3 12.4 10.5 5.8 7.1 6.3 3.0 9.4 12.7 21.5 51.3 27.1 23.5 11.5 37.2 8.0 10.6 10.2 19.2 17.7 15.7 19.5 7.2 16.2 14.7 12.5 11.9 19.3 15.6 3.9 8.7 15.6 19.4 22.4 14.9 10.9 7.8 44.6 10.7 8.8 13.2 14.3 26.7 2.5 22.1 10.8 13.4 20.0 47.1 39.6 12.6 8.2 17.3 22.0 24.1 9.3 19.2 12.4 20.6 13.9 12.3 6.2 33.2 49.1 11.4 12.4 13.2 13.3 13.6 12.2 7.1 13.9 16.7 0.0 19.8 16.6 15.0 10.3 17.0 43.0 9.7 11.6 30.6 13.0 10.7 FOXM1 "FKHL16, HFH-11, HNF-3, INS-1, MPHOSPH2, MPP2, TGT3, trident" ENSG00000111206 "Forkhead box M1" Q08050 12 2857680-2877174 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Cell cycle, DNA damage, DNA repair, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 25.0;lymphoid tissue: 32.2;testis: 21.4" "Cell type enhanced" "Detected in many" "Early spermatids: 22.4;Erythroid cells: 18.7;Extravillous trophoblasts: 18.2;Late spermatids: 25.5;Plasma cells: 19.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" CAB017832 Uncertain Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Cytosol" NA Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nucleoli, Nucleoli rim" Cytosol "CAB017832: " "unprognostic (3.18e-2)" "unprognostic (1.69e-1)" "unprognostic (1.22e-2)" "unprognostic (1.09e-2)" "unprognostic (4.30e-2)" "unprognostic (3.75e-2)" "prognostic unfavorable (1.95e-6)" "prognostic unfavorable (2.92e-4)" "unprognostic (1.01e-2)" "unprognostic (3.25e-2)" "prognostic unfavorable (3.03e-5)" "unprognostic (6.09e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.80e-2)" "unprognostic (1.87e-1)" "unprognostic (1.29e-1)" "unprognostic (1.94e-1)" 1.9 1.1 0.4 9.4 0.5 25.0 1.8 0.8 0.8 1.7 0.2 10.5 9.7 1.7 0.2 11.1 0.8 1.5 0.5 0.8 0.3 0.7 1.2 1.8 11.3 0.4 0.9 0.3 0.4 0.4 0.1 6.1 0.6 0.7 12.5 1.1 1.9 0.8 0.6 6.4 8.8 7.5 0.1 3.1 5.2 21.4 1.0 32.2 0.9 0.3 15.2 3.0 3.2 0.6 133.0 129.5 101.3 92.2 14.2 19.0 129.2 84.0 80.4 165.2 147.2 166.9 114.8 84.5 17.7 119.8 188.5 100.2 153.1 76.1 160.0 159.8 80.3 94.7 121.6 71.6 2.0 79.2 75.0 9.9 8.3 154.4 106.1 39.1 117.8 96.8 55.6 184.9 130.5 122.6 108.3 36.8 225.6 136.1 95.4 77.3 149.8 44.1 38.1 82.7 56.3 89.1 106.7 90.4 46.6 189.4 87.1 87.8 48.0 134.3 200.5 160.4 300.4 24.7 44.3 122.1 63.1 74.3 147.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.4 0.5 0.8 0.8 0.8 0.3 0.4 0.9 0.6 0.1 1.0 0.6 0.1 0.0 1.3 0.7 2.4 2.9 1.3 1.0 1.2 2.0 1.7 1.3 0.5 1.5 0.8 1.8 4.2 7.1 0.8 6.6 1.9 0.2 22.4 1.2 2.1 2.5 0.0 18.7 1.1 0.0 18.2 3.2 10.2 2.4 0.0 15.4 3.6 0.8 9.1 5.0 0.6 7.5 2.0 4.2 1.2 25.5 0.9 2.4 0.0 0.0 1.1 0.6 1.0 0.5 1.0 0.3 0.3 0.7 19.9 1.0 1.4 0.4 0.2 4.0 0.0 1.2 3.0 15.0 9.9 10.2 1.4 1.9 3.3 0.9 12.9 1.9 FOXP1 "12CC4, hFKH1B, HSPC215, QRF1" ENSG00000114861 "Forkhead box P1" Q9H334 3 70954708-71583989 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 41.1" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTEC/SVTERT24-B: 95.0" "Low region specificity" "Detected in all" "HPA003876, CAB011501" Supported Supported Nucleoplasm NA NA "Cluster 30: Non-specific - Translation" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "CAB011501: AB_732428, HPA003876: AB_1078907" "unprognostic (2.31e-1)" "unprognostic (4.35e-3)" "unprognostic (2.09e-2)" "unprognostic (3.54e-2)" "unprognostic (2.69e-1)" "unprognostic (2.81e-3)" "unprognostic (1.68e-1)" "unprognostic (1.00e-1)" "unprognostic (1.23e-1)" "unprognostic (2.03e-1)" "unprognostic (4.38e-3)" "unprognostic (3.40e-1)" "unprognostic (6.14e-2)" "unprognostic (1.05e-1)" "unprognostic (8.65e-2)" "unprognostic (1.27e-1)" "unprognostic (6.05e-2)" 16.5 3.8 5.0 20.3 41.1 38.5 14.5 0.3 12.5 11.2 9.9 28.7 12.2 15.3 6.5 23.0 14.3 21.0 12.7 7.8 0.0 7.0 13.0 22.9 22.2 3.1 6.7 32.4 16.8 6.5 9.1 13.7 0.9 21.2 23.4 2.6 29.7 9.6 8.2 10.9 15.3 22.7 0.1 17.8 20.6 14.4 6.6 26.3 14.5 11.1 25.4 21.6 14.2 8.1 9.6 8.0 16.8 13.2 8.4 21.3 8.2 26.3 30.9 22.0 17.4 51.9 11.2 31.1 4.3 12.9 17.6 6.9 31.0 22.8 40.3 7.8 11.7 13.0 17.0 52.7 20.5 25.7 31.6 21.7 10.3 95.0 42.1 18.3 36.6 15.4 13.6 36.7 10.8 42.6 11.9 9.3 19.7 7.2 39.9 38.0 30.7 4.7 18.8 30.1 14.5 27.6 32.6 7.7 1.9 15.9 5.6 21.9 47.7 34.9 14.3 48.9 42.2 9.0 7.1 41.8 22.5 35.7 7.5 46.9 15.3 15.2 18.3 13.1 19.4 58.1 38.7 22.6 13.0 62.2 60.8 40.0 27.0 22.2 25.3 21.7 35.9 28.8 5.0 41.1 0.3 12.5 7.8 0.0 3.1 6.7 0.9 0.1 6.6 8.1 158.8 73.7 121.3 130.9 266.5 183.0 170.6 58.2 176.4 30.3 98.5 115.1 42.1 148.7 72.0 33.1 18.8 47.2 122.9 118.1 31.3 79.0 156.0 116.3 48.2 184.9 271.6 111.5 391.0 95.1 12.6 90.4 95.8 128.0 219.8 117.7 184.9 72.3 49.5 6.7 139.9 231.2 154.6 117.6 209.0 89.6 42.0 101.3 37.4 414.1 120.3 15.5 116.4 184.5 286.4 124.8 102.8 24.8 66.0 178.8 91.7 19.4 83.7 42.8 92.1 102.9 119.4 13.7 33.6 111.5 101.4 52.4 168.1 33.1 157.2 146.3 FOXP2 "CAGH44, SPCH1, TNRC10" ENSG00000128573 "Forkhead box P2" O15409 7 114086327-114693772 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 18.8" "Group enriched" "Detected in many" 4 "Excitatory neurons: 186.8;Microglial cells: 288.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AF22: 21.0;RH-30: 37.3;THP-1: 11.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000382, HPA000383, HPA001679" Enhanced Enhanced Nucleoplasm NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "HPA000382: AB_1078908, HPA000383: AB_1078909, HPA001679: AB_2666415" "unprognostic (1.21e-1)" "unprognostic (7.85e-2)" "unprognostic (4.89e-2)" "unprognostic (8.83e-3)" "unprognostic (4.66e-1)" "unprognostic (3.69e-4)" "unprognostic (2.04e-2)" "unprognostic (6.22e-2)" "unprognostic (2.17e-1)" "unprognostic (6.70e-3)" "unprognostic (1.22e-1)" "unprognostic (1.77e-1)" "unprognostic (8.04e-2)" "unprognostic (4.16e-3)" "unprognostic (2.84e-1)" "unprognostic (9.81e-2)" "unprognostic (4.19e-2)" 1.9 1.3 1.8 1.9 1.3 0.4 2.0 0.0 10.1 5.0 0.0 18.8 2.5 8.0 1.7 6.1 3.4 3.5 1.4 2.7 0.9 2.0 2.5 1.5 1.0 1.5 6.9 9.7 4.6 0.6 0.9 0.5 1.9 2.2 5.2 3.2 2.8 1.4 3.2 3.7 3.2 7.7 0.0 0.5 4.2 1.3 2.6 0.2 4.9 1.8 0.7 6.1 4.3 5.2 0.4 3.2 21.0 0.0 4.9 6.2 1.3 3.5 3.6 0.7 0.4 1.6 0.3 0.3 0.8 1.2 0.1 0.5 0.8 0.0 0.1 0.2 7.0 8.0 4.6 6.6 0.0 0.5 0.5 1.3 0.8 0.1 0.0 1.3 0.0 0.0 1.8 3.0 0.8 1.5 1.8 1.2 1.1 0.4 1.0 0.6 37.3 7.9 0.5 8.6 5.1 2.2 0.0 1.3 1.1 1.2 1.0 11.9 1.6 1.3 0.6 2.0 0.7 6.3 0.7 1.0 1.5 0.8 0.6 9.7 5.5 11.4 5.9 7.4 5.8 10.1 6.4 6.3 6.7 8.2 6.5 7.4 5.5 6.6 6.3 16.6 10.7 20.5 1.8 1.3 0.0 10.1 2.7 0.9 1.5 6.9 1.9 0.0 2.6 5.2 0.5 0.0 8.2 5.5 0.0 30.7 2.9 5.5 48.3 0.1 1.8 1.3 1.6 10.0 7.3 3.7 2.1 0.1 0.0 4.8 0.0 0.1 9.7 0.1 1.2 1.9 4.2 0.0 186.8 5.4 0.0 20.6 1.1 0.0 0.0 16.2 8.2 11.7 0.2 13.5 6.4 11.5 2.0 1.6 5.6 6.2 5.3 0.4 3.6 288.6 0.0 27.7 0.0 5.5 4.6 1.3 18.5 0.7 0.6 2.3 8.6 3.8 11.3 1.3 0.0 25.5 1.7 2.4 1.4 25.3 25.6 0.3 0.3 4.2 11.5 4.0 FZD1 DKFZp564G072 ENSG00000157240 "Frizzled class receptor 1" Q9UP38 7 91264433-91271326 "Cancer-related genes, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Transporters" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 44.9;Cholangiocytes: 45.8;Horizontal cells: 141.3;Peritubular cells: 45.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 2.0;non-classical monocyte: 2.8" "Lineage enriched" "Detected in single" 5 "monocytes: 2.8" "Cell line enhanced" "Detected in many" "AF22: 24.8;HSkMC: 32.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB013008 Approved Supported "Plasma membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "CAB013008: " "unprognostic (1.46e-1)" "unprognostic (1.70e-1)" "unprognostic (1.15e-1)" "unprognostic (3.16e-2)" "unprognostic (4.51e-3)" "unprognostic (2.09e-1)" "unprognostic (5.29e-3)" "unprognostic (3.70e-2)" "unprognostic (2.36e-2)" "unprognostic (5.48e-3)" "unprognostic (2.14e-1)" "unprognostic (7.39e-3)" "prognostic favorable (8.87e-7)" "unprognostic (1.05e-2)" "unprognostic (4.16e-2)" "unprognostic (5.53e-2)" "unprognostic (4.13e-2)" 5.4 4.4 2.4 2.7 2.5 1.1 10.7 5.8 2.4 9.9 11.1 5.9 5.1 8.6 4.3 5.2 5.5 5.7 12.7 4.7 2.9 9.6 2.5 10.7 1.3 2.5 6.2 10.1 4.7 2.4 3.9 10.0 2.3 10.3 3.7 2.0 9.0 16.4 1.9 10.4 5.1 5.3 2.3 3.2 4.6 1.6 3.4 1.8 20.5 2.4 1.3 6.4 11.2 2.0 0.8 2.5 24.8 2.6 19.8 17.0 4.5 9.2 5.8 3.3 2.3 1.1 4.3 0.0 2.2 5.9 4.2 4.7 3.9 2.0 2.2 0.0 4.9 0.2 4.6 1.3 1.4 4.2 1.0 32.3 3.6 7.6 2.4 12.6 0.7 2.8 1.5 3.6 9.7 6.2 0.8 1.1 6.4 1.3 4.2 5.1 15.3 0.4 5.3 11.8 3.4 6.5 7.0 5.6 1.6 5.7 3.0 3.8 3.8 13.9 10.4 15.0 3.8 3.3 2.5 0.4 15.0 3.5 16.5 0.0 0.6 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 2.8 0.0 0.0 0.2 2.4 2.5 5.8 2.4 4.7 2.9 2.5 6.2 2.3 2.3 3.4 2.0 5.7 3.2 1.5 4.6 1.1 4.2 44.9 7.0 10.8 1.6 27.7 29.5 18.5 45.8 4.6 12.9 2.1 3.4 0.6 7.4 0.0 4.3 0.3 12.0 13.1 4.5 3.5 0.8 0.6 2.0 2.2 18.5 2.0 15.7 12.7 1.8 15.4 0.9 3.5 141.3 1.0 3.0 4.1 17.4 16.2 1.1 33.2 14.3 17.8 1.9 4.6 3.0 1.0 1.0 0.2 1.9 4.8 45.1 0.4 11.7 6.0 11.6 2.4 2.9 0.0 6.2 10.3 0.5 3.7 9.1 5.1 2.1 0.6 2.6 4.6 7.3 FZD3 ENSG00000104290 "Frizzled class receptor 3" Q9NPG1 8 28494205-28574267 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "Neurogenesis, Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 14.7" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 98.0;Excitatory neurons: 155.9;Inhibitory neurons: 82.3;Rod photoreceptor cells: 87.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 9.3" "Group enriched" "Detected in many" 5 "dendritic cells: 9.3;T-cells: 2.3" "Cell line enhanced" "Detected in many" "AF22: 53.2;Karpas-707: 27.9;SCLC-21H: 39.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB024995, HPA042320" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 12: NES - Nervous system development" "Cluster 46: Photoreceptor cells - Phototransduction" Vesicles Nucleoplasm "CAB024995: , HPA042320: AB_2677948" "unprognostic (1.21e-1)" "unprognostic (1.73e-1)" "prognostic favorable (1.17e-4)" "unprognostic (1.31e-1)" "unprognostic (1.07e-1)" "unprognostic (2.57e-4)" "unprognostic (1.69e-2)" "unprognostic (4.26e-4)" "unprognostic (2.11e-1)" "prognostic favorable (3.71e-4)" "unprognostic (2.86e-2)" "unprognostic (1.68e-2)" "unprognostic (1.09e-2)" "unprognostic (1.38e-1)" "unprognostic (4.44e-2)" "unprognostic (3.77e-2)" "unprognostic (6.09e-3)" 1.0 2.9 5.2 1.5 6.7 1.5 2.3 5.7 9.9 2.4 13.8 2.2 1.3 3.4 6.9 1.9 3.5 1.3 1.1 6.8 4.0 2.6 0.6 1.0 2.1 1.8 5.4 7.0 3.5 4.2 3.8 1.3 4.2 4.3 1.2 14.7 3.3 5.5 1.2 1.5 1.0 2.4 0.9 0.6 2.5 5.0 3.2 1.8 3.4 1.3 1.4 1.9 1.6 2.6 14.8 3.1 53.2 10.2 0.0 0.8 7.9 0.5 1.1 3.0 1.3 3.1 3.1 6.9 2.6 0.3 6.6 5.2 8.0 8.8 2.1 9.1 5.8 4.8 1.0 2.0 0.0 2.7 7.9 0.6 4.1 0.2 2.3 0.6 0.6 7.3 3.5 27.9 0.1 3.7 0.2 5.8 13.3 6.4 4.6 3.3 8.0 6.8 4.0 4.4 39.6 10.7 2.9 7.5 8.7 7.0 7.4 4.0 0.0 0.0 14.3 2.0 3.7 5.1 6.1 6.7 4.2 0.0 2.7 0.7 0.2 0.0 1.6 0.2 2.1 1.1 1.2 2.3 0.9 0.6 1.6 1.6 0.1 0.9 0.0 9.3 0.0 0.7 5.2 6.7 5.7 9.9 6.8 4.0 1.8 5.4 4.2 0.9 3.2 2.6 1.7 9.6 12.0 65.6 5.6 6.6 7.9 17.0 10.8 28.1 21.6 11.7 6.0 4.3 17.7 9.2 98.0 10.5 15.7 1.4 1.9 12.1 25.7 24.2 18.7 4.3 28.7 5.0 155.9 14.9 9.7 8.8 8.2 27.7 5.7 29.3 8.6 3.0 4.2 21.9 82.3 6.3 8.2 1.0 7.4 11.9 48.1 2.1 33.8 14.0 0.7 17.0 2.1 52.8 14.3 11.8 3.4 51.1 17.2 14.1 0.8 11.4 17.5 87.1 26.3 8.6 15.0 58.4 45.6 5.6 4.7 4.8 5.0 15.0 5.4 7.7 GABRP ENSG00000094755 "Gamma-aminobutyric acid type A receptor subunit pi" O00591 5 170763350-170814047 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Chloride channel, Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "breast: 152.3;esophagus: 171.5" "Cell type enhanced" "Detected in many" "Breast glandular cells: 169.0;Breast myoepithelial cells: 113.2;Club cells: 83.1;Endometrial ciliated cells: 146.0;Glandular and luminal cells: 464.0;Urothelial cells: 146.6" "Group enriched" "Detected in many" 4 "breast cancer: 35.4;cervical cancer: 49.3;endometrial cancer: 16.8;pancreatic cancer: 41.9;stomach cancer: 25.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 11.8" "Group enriched" "Detected in many" 8 "granulocytes: 11.8;monocytes: 5.7" "Cell line enhanced" "Detected in many" "A-431: 215.1;EFO-21: 236.8;HeLa: 166.8;PC-3: 331.3;SuSa: 418.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" CAB014883 Uncertain NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 38: EFO-21 - Unknown function" "Cluster 44: Endometrium - Transcription" "CAB014883: " "unprognostic (3.98e-3)" "prognostic favorable (3.37e-4)" "unprognostic (8.34e-2)" "unprognostic (1.57e-1)" "unprognostic (8.90e-2)" "unprognostic (1.27e-1)" "unprognostic (7.89e-2)" "unprognostic (4.97e-3)" "unprognostic (3.72e-1)" "unprognostic (4.93e-3)" "unprognostic (1.30e-3)" "unprognostic (2.30e-1)" "unprognostic (1.40e-2)" "unprognostic (1.60e-1)" "unprognostic (1.82e-1)" "unprognostic (5.92e-3)" "unprognostic (6.52e-3)" 4.5 3.6 10.4 7.3 10.5 9.9 152.3 15.8 16.2 13.1 5.4 4.2 15.4 48.6 19.0 171.5 12.9 27.3 5.4 7.6 23.0 6.1 7.1 14.7 5.7 12.5 6.1 3.9 23.8 2.0 2.0 9.1 10.6 12.7 4.9 42.1 35.8 16.6 13.7 19.0 16.2 2.6 2.7 7.4 27.4 8.3 10.4 4.7 6.1 2.7 42.2 5.4 29.4 17.9 215.1 9.9 10.1 7.0 0.7 4.3 23.8 3.8 1.5 0.5 0.6 38.1 23.6 3.3 236.8 1.1 2.3 75.7 6.4 0.5 0.6 3.5 7.6 14.1 166.8 5.7 0.8 5.1 11.2 1.6 3.0 2.8 1.8 8.0 1.4 13.4 57.6 26.5 0.4 6.7 9.5 4.7 84.5 3.7 331.3 13.7 6.6 8.2 13.8 11.6 8.2 4.0 76.5 3.9 2.2 418.8 4.2 2.4 8.8 19.1 69.3 15.7 15.7 10.0 6.7 6.3 2.6 13.9 2.9 11.8 1.9 6.1 0.4 1.5 1.1 0.3 0.4 0.3 0.6 0.7 0.5 0.5 4.5 0.2 5.7 0.9 0.6 2.3 10.4 10.5 15.8 16.2 7.6 23.0 12.5 6.1 10.6 2.7 10.4 17.9 1.1 3.2 0.6 0.0 0.9 0.0 14.9 44.4 0.0 0.0 169.0 113.2 0.7 51.5 83.1 1.8 0.0 5.2 2.3 0.0 0.0 10.4 0.0 146.0 48.8 3.8 0.0 0.0 0.3 13.8 0.6 2.4 2.0 464.0 0.0 0.0 0.0 0.1 2.3 0.0 0.2 0.3 12.2 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 56.6 0.1 0.0 0.0 24.2 0.1 0.1 34.0 0.0 0.0 0.2 5.9 0.0 0.0 4.5 0.0 5.7 2.7 0.0 0.6 146.6 GALNT1 GalNAc-T1 ENSG00000141429 "Polypeptide N-acetylgalactosaminyltransferase 1" Q10472 18 35581117-35711834 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 331.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012628 Uncertain "Intracellular and membrane" NA NA 2600000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 37: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA012628: AB_1849439" "unprognostic (9.81e-2)" "unprognostic (1.01e-1)" "unprognostic (4.39e-2)" "unprognostic (2.73e-1)" "unprognostic (2.08e-1)" "unprognostic (2.83e-2)" "unprognostic (1.96e-2)" "unprognostic (7.06e-2)" "unprognostic (2.03e-2)" "unprognostic (1.51e-2)" "unprognostic (3.00e-2)" "unprognostic (1.00e-1)" "unprognostic (3.47e-2)" "unprognostic (4.38e-2)" "unprognostic (2.74e-2)" "unprognostic (1.07e-2)" "unprognostic (8.60e-2)" 28.9 20.6 11.9 27.4 12.1 26.0 37.2 12.3 14.2 26.5 15.1 42.8 42.9 19.4 19.7 57.6 15.9 28.9 23.8 10.9 14.4 17.4 45.9 23.3 33.5 13.1 13.2 16.9 24.6 12.2 13.5 52.0 13.5 25.4 41.1 17.1 46.8 18.0 29.0 52.4 49.3 22.7 13.1 25.4 27.1 16.9 13.1 18.6 30.0 37.3 40.8 70.5 27.0 13.9 32.5 34.9 40.5 37.6 78.5 74.0 53.4 33.2 35.4 30.3 27.4 21.0 61.9 38.3 34.9 36.0 28.7 24.4 20.2 63.8 48.1 45.0 18.5 48.7 62.8 48.8 39.2 106.6 62.1 50.7 59.7 47.6 52.1 90.1 331.4 30.8 14.8 49.3 118.9 26.1 31.6 40.5 41.6 33.5 16.4 38.9 53.0 18.5 124.8 148.9 21.8 42.9 59.4 43.0 36.2 77.1 32.9 82.8 116.3 55.7 22.5 37.0 37.1 70.1 35.7 72.5 39.1 72.1 29.5 7.2 3.4 7.6 3.2 4.5 3.6 4.1 2.2 2.9 4.0 2.4 2.0 3.0 4.3 4.6 6.6 4.4 2.5 1.4 11.9 12.1 12.3 14.2 10.9 14.4 13.1 13.2 13.5 13.1 13.1 13.9 85.6 80.1 44.1 35.9 33.4 29.8 28.4 28.8 22.2 31.3 77.2 43.8 43.3 48.6 39.9 16.5 12.5 31.0 44.8 109.1 7.9 42.6 1.4 77.6 44.7 41.7 38.9 30.9 57.5 39.9 92.7 49.8 26.0 73.0 20.3 51.7 35.7 71.3 77.9 85.8 56.3 59.0 16.2 58.8 37.1 2.9 19.0 56.7 19.6 57.1 41.3 105.9 28.8 54.3 56.8 58.5 51.4 18.0 36.7 54.4 76.8 22.0 33.5 28.5 13.1 55.2 28.7 6.5 12.2 26.3 82.1 33.2 33.7 50.3 85.3 52.8 GAN "GAN1, GIG, KLHL16" ENSG00000261609 Gigaxonin Q9H2C0 16 81314944-81390809 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 24.8" "Cell type enhanced" "Detected in many" "Suprabasal keratinocytes: 130.4;Urothelial cells: 188.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 10.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011825, HPA049473" Approved Supported Microtubules NA NA "Cluster 15: NK-cells - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 22: Epithelial cell types - Mixed function" Microtubules "CAB011825: AB_732515, HPA049473: AB_2680782" "unprognostic (1.78e-1)" "unprognostic (1.55e-1)" "unprognostic (8.23e-2)" "unprognostic (2.51e-2)" "unprognostic (8.37e-2)" "unprognostic (1.43e-1)" "unprognostic (2.42e-4)" "unprognostic (1.90e-1)" "unprognostic (3.86e-1)" "unprognostic (1.20e-1)" "unprognostic (1.22e-3)" "unprognostic (5.91e-3)" "unprognostic (3.12e-3)" "unprognostic (5.93e-2)" "unprognostic (9.98e-2)" "unprognostic (1.46e-2)" "unprognostic (5.86e-2)" 1.3 0.9 7.3 0.7 5.7 0.7 2.4 6.6 4.7 2.6 1.0 2.3 0.8 1.3 1.1 5.4 1.3 0.6 1.5 6.9 8.8 1.0 1.1 1.7 0.7 9.3 8.6 1.4 1.2 0.8 1.4 0.8 5.5 2.0 1.2 3.2 2.3 0.7 1.5 24.8 1.4 0.9 8.7 0.9 1.8 0.9 8.7 0.9 1.1 1.4 1.3 1.5 4.3 9.2 1.6 2.0 1.5 2.1 1.9 1.0 10.4 1.2 0.7 0.8 0.3 5.1 1.8 2.5 1.4 1.6 0.4 3.1 2.7 1.3 1.8 0.6 1.4 2.2 1.8 4.1 2.0 2.1 2.4 1.1 3.8 1.3 3.5 1.1 1.7 2.1 2.8 1.1 1.1 9.1 1.9 2.9 4.0 2.2 0.6 3.7 1.4 1.0 1.6 5.0 1.5 1.0 4.3 4.2 1.4 3.6 2.9 2.0 2.5 2.3 2.1 0.8 1.9 2.2 2.7 5.8 1.2 2.4 1.7 0.7 0.4 0.2 0.8 0.4 0.7 0.4 0.8 0.6 0.2 0.5 0.7 0.9 0.3 0.9 0.3 0.9 0.6 0.2 7.3 5.7 6.6 4.7 6.9 8.8 9.3 8.6 5.5 8.7 8.7 9.2 12.2 12.8 8.2 69.5 9.9 91.3 66.8 15.0 34.1 28.4 15.4 18.5 12.5 7.2 29.5 5.5 89.6 19.3 17.4 27.5 0.0 9.4 2.3 11.6 19.3 14.7 5.4 12.6 21.2 6.7 15.4 14.1 17.3 14.0 1.3 7.2 12.1 6.7 5.6 23.5 29.5 15.1 10.2 6.8 30.9 4.6 9.6 8.6 37.4 14.0 7.5 14.0 9.2 22.1 18.3 18.6 16.8 12.8 11.0 75.0 14.8 3.8 30.1 43.8 6.6 20.2 17.6 11.9 16.4 67.1 130.4 21.3 16.1 5.3 15.6 188.7 GCSAML "C1orf150, FLJ44728" ENSG00000169224 "Germinal center associated signaling and motility like" Q5JQS6 1 247507058-247577690 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.4;prostate: 5.5" "Cell type enriched" "Detected in some" 24 "granulocytes: 223.3" "Cancer enriched" "Detected in single" 13 "prostate cancer: 1.9" "Region enriched" "Detected in some" 5 "cerebellum: 6.4" "Immune cell enriched" "Detected in single" 661 "basophil: 227.7" "Lineage enriched" "Detected in single" 661 "granulocytes: 227.7" "Group enriched" "Detected in some" 71 "HEL: 151.8;HMC-1: 564.8" "Low region specificity" "Detected in all" "HPA027507, HPA027510" Uncertain Approved Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" Cytosol "HPA027507: AB_10600756, HPA027510: AB_2672309" "unprognostic (5.68e-2)" "unprognostic (1.86e-1)" "unprognostic (4.07e-3)" "unprognostic (3.48e-2)" "unprognostic (1.72e-1)" "unprognostic (2.76e-4)" "unprognostic (3.21e-1)" "unprognostic (6.14e-2)" "unprognostic (5.42e-2)" "unprognostic (2.00e-1)" "unprognostic (1.11e-1)" "unprognostic (1.81e-1)" "unprognostic (9.51e-3)" "unprognostic (3.13e-2)" "unprognostic (2.83e-1)" "unprognostic (1.24e-1)" "unprognostic (1.40e-2)" 0.5 0.2 0.4 0.8 0.4 1.8 1.0 6.4 0.7 0.7 0.4 1.2 1.5 0.8 0.5 1.1 0.3 1.4 0.2 0.3 0.4 0.1 0.2 2.1 0.3 0.4 0.3 0.1 0.4 0.1 0.0 0.3 1.2 5.5 1.5 1.2 0.3 0.4 0.2 0.7 1.4 0.6 0.1 0.4 0.9 3.4 0.4 0.7 0.3 0.7 0.2 0.7 0.3 1.2 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.8 0.8 0.2 0.1 0.0 0.1 151.8 0.2 0.0 0.0 0.3 564.8 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 1.0 0.1 0.3 0.3 5.0 0.2 0.1 0.0 0.2 0.1 0.3 0.0 0.1 0.1 0.4 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.5 0.4 0.0 0.0 0.3 0.2 0.0 2.3 0.1 0.4 227.7 0.1 0.2 0.2 0.2 0.2 0.1 0.2 0.2 0.1 0.3 0.3 0.2 0.2 0.2 0.2 0.1 0.2 0.5 0.4 0.4 6.4 0.7 0.3 0.4 0.4 0.3 1.2 0.1 0.4 1.2 0.0 0.0 4.4 0.0 0.1 0.6 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 1.9 0.0 9.1 0.0 0.1 0.6 0.0 5.0 0.4 0.0 0.0 0.3 0.0 0.0 223.3 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.7 7.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.3 2.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 8.3 1.7 0.0 0.6 0.0 1.4 0.1 0.0 0.2 GDF7 BMP12 ENSG00000143869 "Growth differentiation factor 7" Q7Z4P5 2 20667144-20679243 "Predicted secreted proteins" "Cytokine, Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 9.8;seminal vesicle: 22.4" "Group enriched" "Detected in some" 12 "Endometrial stromal cells: 137.0;Granulosa cells: 83.7" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in single" "cerebral cortex: 2.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 1.7;Hep G2: 4.4;RT4: 8.3;SH-SY5Y: 3.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA069106 Approved Vesicles "Secreted in other tissues" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 15: RT4 - Unknown function" "Cluster 36: Stromal cells - Cell proliferation" Vesicles "HPA069106: " "unprognostic (1.35e-1)" "unprognostic (9.93e-3)" "unprognostic (5.10e-1)" "unprognostic (2.44e-3)" "unprognostic (1.35e-1)" "unprognostic (2.06e-3)" "unprognostic (8.63e-3)" "unprognostic (6.31e-3)" "unprognostic (8.00e-3)" "unprognostic (3.85e-1)" "unprognostic (4.41e-2)" "unprognostic (1.14e-1)" "unprognostic (1.28e-3)" "unprognostic (8.02e-3)" "unprognostic (2.05e-1)" "unprognostic (3.44e-2)" "unprognostic (1.89e-3)" 0.4 0.4 0.2 1.0 0.5 0.2 0.1 0.0 2.5 9.8 0.0 0.5 0.2 7.2 3.3 0.9 0.7 0.6 0.8 0.4 0.1 3.6 5.0 0.4 2.3 0.3 0.1 0.3 0.6 0.1 0.3 0.8 0.0 3.8 0.2 0.1 0.1 22.4 0.0 1.3 1.6 1.1 0.0 1.3 0.7 0.2 0.3 0.2 0.2 0.6 1.8 1.1 6.6 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.7 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.1 1.2 8.3 0.0 3.3 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 2.5 0.4 0.1 0.3 0.1 0.0 0.0 0.3 0.6 0.1 6.4 0.0 0.0 2.6 0.0 0.6 0.0 0.0 0.5 0.0 0.0 8.8 2.8 3.1 5.5 0.0 0.0 0.1 0.1 1.9 0.1 0.1 3.5 137.0 1.8 0.0 2.7 0.2 0.0 0.1 1.3 0.0 2.9 0.0 83.7 0.0 8.2 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.7 0.0 4.1 0.7 0.0 0.0 0.3 7.1 0.5 1.0 0.0 0.0 0.0 0.8 0.0 0.0 1.5 GINS1 "KIAA0186, PSF1" ENSG00000101003 "GINS complex subunit 1" Q14691 20 25407673-25452628 "Disease related genes, Predicted intracellular proteins" "DNA replication" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 7.3;testis: 9.0" "Cell type enhanced" "Detected in many" "Early spermatids: 60.2;Erythroid cells: 14.7;Extravillous trophoblasts: 17.9;Late spermatids: 21.9;Spermatocytes: 14.2;Spermatogonia: 19.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051185 Uncertain Approved Nucleoplasm NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA051185: AB_2681378" "unprognostic (6.10e-3)" "unprognostic (2.58e-1)" "unprognostic (5.37e-3)" "unprognostic (1.74e-3)" "unprognostic (2.00e-1)" "unprognostic (3.11e-2)" "prognostic unfavorable (4.61e-7)" "unprognostic (5.86e-3)" "unprognostic (1.42e-2)" "unprognostic (1.32e-2)" "prognostic unfavorable (5.62e-4)" "unprognostic (1.44e-1)" "prognostic unfavorable (5.42e-11)" "unprognostic (5.24e-2)" "unprognostic (1.03e-1)" "unprognostic (4.60e-2)" "unprognostic (2.55e-1)" 0.7 0.6 0.9 3.2 0.8 3.4 1.6 1.8 1.0 1.0 0.4 3.2 3.0 1.4 0.7 4.3 0.8 0.8 0.5 0.8 0.5 1.1 1.2 0.5 5.3 0.4 0.5 0.9 0.5 0.6 0.2 2.9 0.6 0.8 3.9 0.8 0.8 0.4 0.5 3.7 2.9 2.0 0.3 1.5 2.0 9.0 0.6 7.3 0.6 0.0 5.9 1.3 1.5 0.9 43.6 38.8 46.5 30.4 2.6 3.5 46.7 18.9 9.1 35.5 37.2 33.7 42.1 53.3 21.0 7.9 26.4 49.0 40.9 34.4 40.7 14.3 14.2 36.7 13.8 41.3 0.9 48.5 16.2 1.7 2.0 33.8 6.9 4.7 19.1 30.1 36.1 33.9 21.2 47.0 75.1 36.0 31.8 30.0 20.0 53.1 53.6 35.7 13.6 28.8 19.4 20.3 19.3 45.3 16.7 26.0 42.9 24.2 8.7 27.7 29.9 18.2 35.1 13.6 41.1 42.0 7.4 46.8 32.0 0.2 0.2 0.1 0.3 0.2 0.1 0.5 0.2 0.1 0.5 0.3 0.1 0.3 0.2 0.4 0.2 0.5 0.8 0.2 0.9 0.8 1.8 1.0 0.8 0.5 0.4 0.5 0.6 0.3 0.6 0.9 0.2 0.0 0.6 1.3 1.5 3.2 1.0 1.5 1.8 1.8 1.1 1.3 0.4 0.0 1.6 1.8 0.0 8.2 0.2 1.9 0.0 1.1 60.2 0.5 1.3 1.1 1.2 14.7 6.4 0.7 17.9 2.0 3.6 1.3 1.3 6.8 0.7 0.7 5.9 0.0 3.7 2.5 0.0 1.6 0.8 21.9 0.6 1.2 0.0 1.0 0.0 1.3 0.0 4.0 1.6 0.4 0.6 1.2 8.9 0.6 0.4 2.1 1.7 0.2 0.0 0.5 1.4 14.2 19.7 5.4 1.4 2.5 0.8 2.0 5.5 0.8 GJA9 "CX58, CX59, GJA10" ENSG00000131233 "Gap junction protein alpha 9" P57773 1 38874069-38881587 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "brain: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "GAMG: 1.0" "Low region specificity" "Detected in all" HPA067850 Uncertain NA NA "Cluster 24: B-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "HPA067850: AB_2685910" "unprognostic (2.00e-1)" "unprognostic (8.78e-2)" "unprognostic (4.55e-2)" "unprognostic (2.66e-1)" "unprognostic (4.79e-2)" "unprognostic (1.20e-2)" "unprognostic (1.95e-1)" "unprognostic (1.75e-1)" "unprognostic (2.75e-2)" "unprognostic (1.90e-2)" "unprognostic (2.63e-1)" "unprognostic (4.11e-3)" "unprognostic (2.32e-2)" 0.1 0.1 0.3 0.0 0.4 0.0 0.0 0.2 0.5 0.1 0.0 0.3 0.2 0.0 0.0 0.4 0.1 0.1 0.5 0.1 0.1 0.1 0.0 0.0 0.1 1.4 1.7 0.1 0.1 0.0 0.2 0.0 0.7 0.1 0.2 0.4 0.2 0.0 0.1 0.5 0.0 0.0 0.0 0.1 0.2 0.8 0.5 0.0 0.2 0.0 0.0 0.2 0.3 0.8 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.1 0.0 0.1 0.3 0.2 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.3 0.1 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.3 0.4 0.2 0.5 0.1 0.1 1.4 1.7 0.7 0.0 0.5 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GJB5 CX31.1 ENSG00000189280 "Gap junction protein beta 5" O95377 1 34755047-34758512 "Cancer-related genes, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "esophagus: 101.0;skin 1: 95.1;vagina: 35.0" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 48.6;Basal prostatic cells: 38.0;Basal respiratory cells: 49.6;Squamous epithelial cells: 63.8;Suprabasal keratinocytes: 83.5;Urothelial cells: 66.2" "Cancer enhanced" "Detected in many" "cervical cancer: 36.7;head and neck cancer: 57.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 29.1;HaCaT: 90.8;HBEC3-KT: 40.7;hTCEpi: 147.4;RT4: 50.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA038146 Uncertain NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA038146: AB_10697242" "unprognostic (2.62e-1)" "unprognostic (1.63e-1)" "unprognostic (3.48e-1)" "unprognostic (5.71e-2)" "unprognostic (8.26e-2)" "unprognostic (3.12e-1)" "unprognostic (7.89e-2)" "unprognostic (2.76e-2)" "unprognostic (5.35e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (1.54e-4)" "unprognostic (4.30e-2)" "unprognostic (1.09e-3)" "unprognostic (2.36e-1)" "unprognostic (2.41e-3)" "unprognostic (5.59e-2)" "unprognostic (5.67e-3)" 0.2 0.1 1.0 0.0 1.0 0.0 3.9 0.6 1.3 12.8 0.0 0.1 0.0 0.1 3.4 101.0 0.6 3.4 0.1 1.4 0.3 0.1 0.4 0.3 0.0 0.4 0.4 0.1 1.1 0.0 0.8 0.6 0.5 5.2 0.1 0.0 13.9 3.1 0.3 95.1 0.2 0.0 0.6 0.1 0.1 2.3 0.7 1.4 0.9 0.1 12.6 7.1 35.0 0.9 29.1 0.3 0.1 0.5 0.0 0.0 0.7 0.1 0.1 0.0 0.0 0.0 2.2 0.0 1.2 0.0 0.3 90.8 0.0 40.7 0.0 0.1 0.0 7.0 0.9 0.0 0.0 0.0 0.0 0.1 147.4 0.0 23.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.5 0.9 0.0 0.0 0.0 0.0 50.9 0.1 0.0 3.6 1.5 0.0 0.4 3.2 0.0 0.1 0.0 0.0 0.0 0.0 0.2 2.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.0 0.6 1.3 1.4 0.3 0.4 0.4 0.5 0.6 0.7 0.9 0.0 0.0 1.1 0.3 0.0 48.6 38.0 49.6 12.5 0.0 2.8 1.9 0.5 0.0 17.2 0.0 0.0 0.7 0.0 0.4 0.0 0.0 0.0 0.5 0.0 0.6 0.0 0.0 0.2 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.1 0.0 4.2 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 19.5 0.0 0.0 12.4 0.0 0.0 0.0 1.4 0.0 0.0 63.8 83.5 0.4 0.2 0.0 0.3 66.2 GK5 MGC40579 ENSG00000175066 "Glycerol kinase 5" Q6ZS86 3 142157527-142225592 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycerol metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cells: 127.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA042606, HPA057998" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 51: Non-specific - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Cytosol" "HPA042606: AB_10795509, HPA057998: AB_2683573" "unprognostic (7.79e-2)" "unprognostic (5.15e-2)" "unprognostic (2.02e-2)" "unprognostic (1.33e-1)" "unprognostic (3.07e-2)" "unprognostic (3.60e-2)" "unprognostic (9.89e-3)" "unprognostic (3.13e-1)" "unprognostic (2.77e-2)" "unprognostic (1.76e-2)" "unprognostic (7.76e-2)" "unprognostic (2.03e-1)" "unprognostic (1.12e-2)" "unprognostic (2.10e-3)" "unprognostic (4.49e-2)" "unprognostic (1.32e-1)" "unprognostic (5.59e-3)" 4.6 7.0 2.3 3.8 2.4 7.8 6.8 4.8 2.7 5.0 7.0 6.8 9.4 5.4 9.0 4.3 6.0 3.2 2.4 2.3 2.4 3.6 2.1 3.8 2.2 4.4 3.1 8.6 4.0 3.1 5.8 1.7 4.0 8.4 7.3 4.7 11.0 4.0 2.5 5.9 8.0 3.3 2.9 2.2 5.2 3.2 3.0 2.1 4.6 1.5 2.4 4.2 4.4 4.6 11.2 2.7 3.9 2.6 8.0 15.2 6.7 3.6 2.5 3.9 2.5 4.2 6.0 7.9 3.2 3.5 4.3 4.6 4.5 3.5 5.2 2.9 4.3 5.2 7.1 3.1 4.3 6.1 6.7 6.2 3.0 2.6 3.4 2.5 2.3 9.1 4.6 4.7 7.2 7.2 5.3 5.0 2.5 7.5 3.1 4.9 4.2 2.9 4.1 6.8 3.8 2.8 10.1 10.5 3.3 2.3 14.8 4.0 2.5 3.1 2.6 6.9 4.1 4.9 5.1 8.1 5.6 3.8 5.3 2.0 0.4 0.3 1.5 0.3 0.7 0.2 0.5 0.5 0.3 0.4 0.3 0.6 1.1 1.5 2.6 0.4 0.2 0.2 2.3 2.4 4.8 2.7 2.3 2.4 4.4 3.1 4.0 2.9 3.0 4.6 13.7 38.5 30.7 31.6 6.8 4.0 12.3 3.7 15.9 30.6 26.6 13.6 10.5 17.2 17.3 27.6 29.2 13.1 80.5 37.4 7.9 14.9 2.8 32.7 22.5 9.7 27.9 8.8 37.6 20.4 7.3 15.2 25.0 39.2 8.8 23.2 5.0 11.8 5.6 15.2 44.1 42.0 0.0 10.0 3.9 5.2 33.8 20.2 3.6 15.9 9.3 10.2 127.7 27.6 75.6 19.3 31.6 46.6 34.6 21.5 69.5 6.1 14.1 33.0 26.3 16.0 9.0 4.0 5.9 19.4 4.0 6.8 21.0 21.1 34.5 17.3 GLIS3 "MGC33662, ZNF515" ENSG00000107249 "GLIS family zinc finger 3" Q8NEA6 9 3824127-4348392 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Congenital hypothyroidism, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.2;choroid plexus: 20.5" "Cell type enriched" "Detected in many" 7 "Astrocytes: 649.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 21.5;HSkMC: 29.5;RPTEC TERT1: 20.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA056426 Approved Supported Nucleoplasm "Intracellular and membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "HPA056426: AB_2683128" "unprognostic (6.24e-2)" "unprognostic (2.30e-2)" "unprognostic (1.54e-1)" "unprognostic (3.63e-3)" "unprognostic (4.10e-1)" "unprognostic (1.88e-1)" "unprognostic (1.81e-2)" "unprognostic (7.14e-2)" "unprognostic (4.66e-2)" "unprognostic (1.26e-1)" "unprognostic (1.17e-1)" "unprognostic (2.63e-1)" "unprognostic (1.91e-3)" "unprognostic (6.88e-3)" "unprognostic (8.54e-2)" "unprognostic (1.04e-1)" "unprognostic (6.35e-2)" 4.3 1.6 5.1 2.1 5.5 0.2 1.9 4.9 4.6 7.8 20.5 2.0 0.7 3.3 2.8 0.5 8.7 6.5 2.9 5.4 10.8 7.8 3.3 3.8 1.1 24.2 18.0 6.6 9.7 2.4 2.4 1.4 11.4 3.3 2.1 1.3 3.1 8.2 1.3 0.8 1.5 2.1 13.7 2.0 1.8 2.8 6.5 0.2 18.6 0.8 0.7 4.0 2.4 13.2 1.0 8.5 2.5 0.0 3.7 9.5 0.4 5.9 21.5 3.1 4.4 1.3 3.4 0.0 4.3 5.5 9.6 0.0 2.0 0.0 6.7 2.5 1.2 0.0 0.4 0.0 11.0 0.9 0.0 29.5 0.0 9.8 1.1 5.8 0.4 0.1 0.0 0.2 2.9 0.4 0.0 1.5 0.2 0.0 0.8 0.0 5.2 0.0 20.8 0.0 0.0 0.0 0.8 0.0 0.0 1.1 0.0 0.0 5.5 3.4 0.9 3.2 13.3 0.0 0.0 0.0 8.1 0.0 3.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 5.1 5.5 4.9 4.6 5.4 10.8 24.2 18.0 11.4 13.7 6.5 13.2 8.1 9.6 24.0 649.7 1.0 1.9 9.3 17.1 0.6 1.0 4.6 1.3 1.6 75.8 34.5 69.9 0.0 3.2 0.3 3.7 0.0 51.0 5.2 79.6 17.5 11.2 43.7 0.0 18.3 22.6 3.2 21.9 4.1 82.3 1.3 1.6 6.8 8.3 2.4 0.0 54.2 1.6 12.2 0.8 4.0 2.4 13.7 3.4 3.6 86.2 2.2 15.6 0.0 26.7 4.1 49.1 3.9 11.3 0.0 16.5 2.4 16.4 35.7 0.4 0.0 34.4 19.0 1.3 7.4 0.6 1.3 4.2 1.2 8.8 6.6 6.1 GLOD4 "C17orf25, CGI-150, HC71" ENSG00000167699 "Glyoxalase domain containing 4" Q9HC38 17 757097-783390 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021623, HPA023246, HPA023248" Enhanced Approved Cytosol NA NA 3500000 "Cluster 27: Non-specific - Gene expression" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "HPA021623: AB_1844365, HPA023246: AB_1844366, HPA023248: AB_1844367" "unprognostic (2.82e-1)" "unprognostic (1.80e-1)" "unprognostic (1.33e-1)" "unprognostic (1.45e-2)" "unprognostic (1.99e-1)" "unprognostic (2.11e-1)" "unprognostic (2.88e-1)" "unprognostic (3.35e-1)" "unprognostic (3.13e-2)" "unprognostic (6.27e-2)" "unprognostic (4.86e-2)" "unprognostic (1.96e-2)" "prognostic favorable (2.18e-6)" "unprognostic (6.21e-3)" "unprognostic (1.33e-1)" "unprognostic (2.46e-1)" "unprognostic (3.02e-1)" 42.5 46.8 27.4 33.5 31.0 22.5 34.5 25.4 33.3 28.4 33.4 71.3 80.5 31.6 33.6 42.9 44.9 32.6 37.3 30.6 36.4 75.7 67.7 31.5 46.9 27.8 27.9 39.9 40.5 37.6 23.2 36.7 28.8 37.8 48.3 25.6 39.5 27.3 39.8 44.3 72.7 31.9 28.3 36.8 85.3 19.4 35.3 35.2 47.4 23.0 40.0 41.5 22.4 27.5 121.1 106.8 120.9 67.1 52.0 51.5 73.8 94.4 57.6 75.0 56.7 87.4 84.0 142.9 100.2 42.8 69.7 85.5 106.6 60.1 78.0 105.4 91.2 69.0 55.7 115.5 51.6 72.1 87.5 36.2 81.9 75.5 66.0 47.7 70.4 116.9 115.1 90.4 80.2 73.9 124.1 55.3 88.7 118.8 36.3 122.7 49.0 65.9 74.5 81.2 54.8 91.8 74.8 53.6 124.6 75.3 66.6 75.2 92.2 71.0 56.8 99.9 120.4 50.3 100.0 89.1 83.6 79.5 75.9 26.1 51.8 48.7 68.1 64.1 73.2 70.0 81.0 82.2 45.9 75.4 68.9 75.7 7.1 64.0 70.4 47.2 99.1 75.9 27.4 31.0 25.4 33.3 30.6 36.4 27.8 27.9 28.8 28.3 35.3 27.5 52.2 57.7 35.2 11.4 48.5 47.9 40.4 91.1 40.5 39.6 39.2 36.3 30.9 54.3 70.4 101.2 29.2 104.5 43.2 39.3 178.1 77.3 34.0 44.0 34.3 43.8 28.9 54.7 12.7 57.4 85.9 41.5 71.4 40.8 40.4 42.1 31.1 58.8 82.3 13.5 13.6 52.0 97.6 30.1 26.5 63.3 38.8 40.8 67.6 7.5 61.7 39.8 44.3 10.1 13.2 58.7 52.0 46.6 27.5 39.4 110.5 186.1 66.8 38.7 46.0 30.3 45.8 23.5 32.9 53.6 54.8 69.1 53.3 57.2 63.7 39.3 GLP1R GLP-1R ENSG00000112164 "Glucagon like peptide 1 receptor" P43220 6 39048781-39091303 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.7;heart muscle: 2.7;pancreas: 7.0" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 2.2;Early spermatids: 1.0;Inhibitory neurons: 1.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NTERA-2: 1.1;SCLC-21H: 2.7" "Region enriched" "Detected in many" 4 "basal ganglia: 20.7" "Low region specificity" "Detected in some" NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (4.06e-3)" "unprognostic (5.38e-6)" "unprognostic (1.80e-2)" "unprognostic (4.16e-2)" "unprognostic (4.98e-2)" "unprognostic (3.55e-1)" "unprognostic (2.11e-1)" "unprognostic (1.38e-1)" "unprognostic (9.76e-2)" "unprognostic (3.29e-1)" "unprognostic (1.73e-1)" "unprognostic (8.60e-3)" "unprognostic (2.47e-1)" "unprognostic (1.15e-2)" "unprognostic (1.42e-2)" 0.1 0.0 0.4 0.0 0.9 0.0 0.6 0.3 0.5 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 2.7 0.6 3.7 0.1 0.0 0.3 0.1 1.1 0.5 0.0 7.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 2.2 0.0 0.0 0.1 0.1 0.0 1.1 0.0 0.9 0.2 1.6 0.1 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.9 0.3 0.5 0.6 3.7 1.1 0.5 1.2 1.1 1.6 0.3 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GLYAT "ACGNAT, GAT" ENSG00000149124 Glycine-N-acyltransferase Q6IB77 11 58640426-58731974 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Detoxification "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "kidney: 571.8;liver: 698.0" "Group enriched" "Detected in some" 6 "Hepatocytes: 346.7;Proximal tubular cells: 1261.0" "Group enriched" "Detected in some" 158 "liver cancer: 21.7;renal cancer: 25.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-937: 1.4" "Not detected" "Not detected" "HPA040251, HPA044094" Enhanced NA NA 21000 "Cluster 81: Kidney & Liver - Metabolism" "Cluster 32: U-937 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA040251: AB_2676902, HPA044094: AB_2678807" "unprognostic (2.15e-2)" "unprognostic (9.38e-4)" "unprognostic (4.60e-2)" "unprognostic (1.65e-3)" "unprognostic (1.83e-1)" "unprognostic (1.60e-1)" "prognostic favorable (1.31e-6)" "unprognostic (2.69e-1)" 47.0 0.1 0.0 0.1 0.1 0.1 8.5 0.1 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.1 0.0 571.8 698.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.1 1.2 0.0 0.1 0.2 0.1 0.0 0.0 0.1 0.3 0.5 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.3 0.3 0.1 0.0 1.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.3 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 11.5 0.0 31.3 0.0 0.1 0.0 0.0 123.3 0.0 6.0 0.0 0.0 0.6 0.0 8.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.8 346.7 0.0 0.0 0.2 0.0 0.0 10.7 0.0 8.2 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1261.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 3.8 0.0 0.0 0.0 GLYATL1B GLYATL1P3 ENSG00000255151 "Glycine-N-acyltransferase like 1B" A0A0U1RQE8 11 59086307-59094786 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 7 "breast: 7.3;lymphoid tissue: 2.8" "Cell type enriched" "Detected in single" 57 "Proximal tubular cells: 5.8" "Cancer enhanced" "Detected in single" "prostate cancer: 0.7" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.5" "Lineage enriched" "Detected in single" 15 "B-cells: 1.5" "Cell line enhanced" "Detected in some" "Daudi: 1.8;T-47d: 1.2;U-266/70: 1.8" HPA039501 Uncertain Uncertain "Golgi apparatus,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Golgi apparatus" Cytosol "HPA039501: AB_2676545" "unprognostic (1.39e-1)" "unprognostic (3.46e-1)" "unprognostic (1.44e-1)" "unprognostic (1.25e-1)" "unprognostic (5.20e-2)" "unprognostic (2.62e-1)" "unprognostic (2.11e-1)" "unprognostic (3.21e-4)" "unprognostic (3.45e-1)" 0.0 0.0 0.0 0.8 0.0 0.0 7.3 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.4 0.8 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.9 0.0 1.8 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GM2A SAP-3 ENSG00000196743 "GM2 ganglioside activator" P17900 5 151212150-151270440 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism, Sphingolipid metabolism" Hydrolase "Disease variant, Gangliosidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 224.7;Hofbauer cells: 100.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "B-cells: 30.9;dendritic cells: 39.6;monocytes: 40.4" "Cell line enhanced" "Detected in all" "BEWO: 207.1;HBEC3-KT: 291.8;hTCEpi: 287.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008063 Enhanced Approved Vesicles,Cytosol "Intracellular and membrane" NA NA 19000000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 27: Brain & Skin - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Vesicles, Cytosol" "HPA008063: AB_1849842" "unprognostic (4.33e-2)" "unprognostic (8.97e-3)" "unprognostic (2.27e-1)" "unprognostic (3.01e-1)" "unprognostic (1.10e-1)" "unprognostic (2.70e-1)" "prognostic unfavorable (1.77e-5)" "unprognostic (1.22e-1)" "unprognostic (1.72e-2)" "unprognostic (1.31e-2)" "unprognostic (1.50e-2)" "unprognostic (5.33e-3)" "unprognostic (9.81e-2)" "unprognostic (4.24e-2)" "unprognostic (4.42e-2)" "unprognostic (3.02e-2)" "unprognostic (1.65e-1)" 17.4 20.5 29.3 30.0 39.7 20.6 28.0 38.9 31.1 30.8 17.9 19.7 15.8 15.1 30.8 56.2 15.4 23.4 26.2 27.1 34.3 11.4 24.8 39.0 61.4 42.6 37.9 21.3 14.9 28.3 6.6 57.9 44.3 21.1 26.3 11.7 17.0 17.9 7.2 81.8 16.3 20.0 39.0 36.0 15.8 11.6 36.2 72.3 13.0 10.5 77.9 40.3 49.5 46.7 22.3 14.8 15.1 71.7 98.0 48.2 207.1 35.0 75.1 19.0 25.6 30.3 26.1 71.9 35.1 26.9 51.1 60.0 16.7 291.8 27.2 41.4 10.5 11.7 16.8 37.9 23.7 19.1 117.1 65.4 287.0 24.4 16.4 26.0 27.6 85.1 11.4 30.7 30.1 9.6 38.4 18.0 10.2 11.4 32.3 17.7 7.1 46.3 18.4 43.3 3.9 13.4 29.1 133.0 58.3 52.0 30.7 22.5 24.6 46.0 17.6 38.3 10.6 75.2 96.8 187.0 53.1 30.1 19.4 7.6 40.4 2.4 3.7 13.6 2.7 30.9 4.3 3.9 39.6 29.8 6.1 4.8 8.7 4.4 3.4 28.0 5.4 18.6 29.3 39.7 38.9 31.1 27.1 34.3 42.6 37.9 44.3 39.0 36.2 46.7 5.8 16.0 23.0 5.5 25.0 14.9 18.5 63.2 26.7 5.8 5.4 15.5 30.9 0.0 29.7 18.4 2.1 53.6 8.3 4.4 1.9 7.2 0.5 5.7 6.8 7.3 3.6 5.0 2.2 8.1 224.7 10.2 10.7 7.7 69.6 16.3 8.6 24.2 100.8 6.7 2.7 5.4 10.2 55.7 32.5 1.6 8.1 67.8 8.8 2.8 52.5 8.0 7.2 3.5 9.5 6.0 4.7 13.9 28.8 6.7 6.2 5.4 19.9 3.7 0.0 7.9 6.9 1.8 4.2 45.6 23.9 52.5 5.6 6.4 6.7 36.5 GNAI1 ENSG00000127955 "G protein subunit alpha i1" P63096 7 79768028-80226181 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Transport" Transducer "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 220.0;Oligodendrocytes: 410.7;Suprabasal keratinocytes: 214.2;Syncytiotrophoblasts: 183.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "NK-cell: 12.8" "Lineage enriched" "Detected in many" 6 "NK-cells: 12.8" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022449, HPA042141" Approved Supported Nucleoplasm,Nucleoli,Centrosome NA NA 1600000 "Cluster 48: NK-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 17: WM-115 - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Centrosome "Nucleoplasm, Nucleoli" "CAB022449: , HPA042141: AB_2677870" "unprognostic (2.29e-1)" "unprognostic (2.83e-2)" "unprognostic (2.64e-2)" "unprognostic (1.54e-1)" "unprognostic (7.05e-2)" "unprognostic (1.18e-1)" "unprognostic (1.92e-2)" "unprognostic (2.08e-2)" "prognostic unfavorable (5.09e-4)" "unprognostic (9.78e-2)" "unprognostic (1.26e-1)" "unprognostic (4.48e-1)" "unprognostic (9.41e-3)" "prognostic unfavorable (6.47e-4)" "unprognostic (1.12e-1)" "unprognostic (1.94e-2)" "unprognostic (1.53e-1)" 47.5 26.2 8.9 2.6 18.8 0.4 34.9 14.9 17.7 18.5 4.4 25.4 4.7 14.8 0.7 19.7 10.9 3.2 9.4 10.8 13.3 36.6 15.2 15.2 2.0 18.8 15.0 17.1 4.5 1.3 10.9 13.6 18.4 8.8 2.6 1.5 10.4 3.0 6.2 47.9 9.9 4.1 15.5 5.9 17.7 13.0 14.2 1.3 14.2 2.9 1.5 24.7 19.9 36.6 2.2 18.6 10.5 0.0 14.5 7.9 9.1 14.3 7.2 5.5 8.7 0.0 3.4 0.0 4.5 9.3 5.1 2.6 7.0 9.5 5.4 0.0 11.9 10.4 12.9 1.2 14.8 1.8 0.0 12.0 19.9 4.1 9.5 4.4 3.5 0.0 0.0 0.1 7.7 0.6 0.0 0.1 6.1 0.2 11.0 8.6 5.2 7.8 15.7 7.0 12.5 9.2 13.5 0.0 10.3 5.4 2.0 0.3 13.0 21.8 15.6 5.1 4.4 0.0 0.0 0.2 6.1 1.2 10.2 1.3 0.4 0.4 0.1 0.4 0.0 0.0 0.1 0.1 1.9 0.1 1.1 0.5 0.3 12.8 1.0 0.2 0.1 0.4 8.9 18.8 14.9 17.7 10.8 13.3 18.8 15.0 18.4 15.5 14.2 36.6 121.1 19.2 13.8 11.4 0.9 220.0 20.6 81.6 35.3 3.9 7.0 7.7 6.7 21.5 42.3 29.5 0.0 83.6 1.3 11.1 88.0 7.2 1.7 23.2 58.5 31.5 19.9 4.2 71.4 3.8 84.6 35.9 4.6 40.3 30.3 43.9 17.5 20.0 10.0 26.9 77.4 7.8 36.7 1.0 28.6 7.0 33.5 3.9 103.2 4.7 2.9 49.1 0.0 53.3 410.7 9.4 6.3 74.4 1.2 17.4 0.9 18.4 36.8 5.0 111.7 10.6 70.8 9.7 45.7 31.9 214.2 183.5 2.9 2.9 10.7 19.2 GNB2 ENSG00000172354 "G protein subunit beta 2" P62879 7 100673567-100679174 "Predicted intracellular proteins, RAS pathway related proteins, Transporters" Transducer "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010032, HPA040736" Approved Supported "Plasma membrane" NA NA 940000 "Cluster 52: Eosinophils - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" "Plasma membrane" "CAB010032: AB_2263466, HPA040736: AB_2677106" "unprognostic (1.55e-1)" "unprognostic (5.76e-2)" "unprognostic (1.01e-3)" "unprognostic (2.76e-1)" "unprognostic (1.11e-2)" "unprognostic (1.94e-1)" "unprognostic (3.68e-3)" "unprognostic (3.52e-1)" "unprognostic (6.58e-2)" "unprognostic (2.54e-1)" "unprognostic (9.79e-3)" "unprognostic (1.70e-1)" "unprognostic (3.75e-2)" "unprognostic (1.24e-1)" "unprognostic (3.19e-1)" "unprognostic (5.29e-2)" "unprognostic (2.98e-1)" 198.4 211.0 131.4 128.3 137.3 207.5 188.0 112.3 179.6 209.4 103.8 168.0 103.2 182.4 63.7 328.4 179.8 105.5 175.9 130.2 138.1 186.1 185.8 210.1 107.9 140.3 130.1 175.3 184.8 98.9 203.3 107.4 123.6 183.0 83.6 20.1 190.8 113.6 175.9 295.5 143.5 113.5 126.3 225.9 172.4 92.9 137.6 90.2 144.8 90.2 105.7 165.2 217.7 120.7 358.6 268.6 222.7 272.5 169.8 199.9 194.3 208.4 288.4 294.3 241.7 205.3 333.7 157.7 216.0 311.3 332.2 243.0 177.7 312.6 103.0 216.9 152.1 120.8 198.7 171.3 282.4 157.7 254.5 259.5 291.1 304.2 244.6 237.6 343.6 132.5 228.6 303.3 270.4 980.0 249.5 450.3 173.5 225.1 290.1 234.3 136.3 253.8 235.4 291.3 241.0 380.1 278.0 449.2 201.3 125.3 192.4 192.1 325.8 313.8 346.8 619.2 266.6 88.8 111.9 240.9 237.1 349.7 443.6 27.6 28.6 70.9 17.5 42.7 16.2 13.6 17.9 15.4 28.1 18.1 11.8 12.4 117.2 15.4 35.9 23.8 23.5 12.5 131.4 137.3 112.3 179.6 130.2 138.1 140.3 130.1 123.6 126.3 137.6 120.7 138.1 57.7 97.0 16.0 104.1 151.8 159.3 72.9 148.0 10.4 105.4 106.0 35.0 100.1 55.5 84.6 4.2 172.4 89.4 285.4 162.4 163.7 32.6 133.5 106.8 136.5 180.4 127.7 12.7 218.7 312.1 117.6 135.1 127.2 44.4 97.6 126.0 69.9 264.4 72.3 10.8 211.2 75.3 198.6 198.8 20.1 144.8 193.5 140.5 15.9 160.8 128.2 96.8 5.0 6.9 257.1 285.6 130.1 122.5 226.5 162.3 107.0 68.3 8.5 65.7 62.0 162.2 34.3 69.6 240.7 194.8 293.9 117.8 88.1 192.2 259.5 GNG7 FLJ00058 ENSG00000176533 "G protein subunit gamma 7" O60262 19 2511219-2702694 "Predicted intracellular proteins, RAS pathway related proteins" Transducer "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 14 "brain: 360.9" "Cell type enhanced" "Detected in many" "B-cells: 145.4;Distal tubular cells: 123.3;Horizontal cells: 169.9;Oligodendrocyte precursor cells: 102.5;Oligodendrocytes: 206.1;Plasma cells: 169.7" "Cancer enhanced" "Detected in all" "glioma: 21.9;melanoma: 20.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 57.2;naive B-cell: 50.1;plasmacytoid DC: 48.0" "Group enriched" "Detected in many" 4 "B-cells: 57.2;dendritic cells: 48.0" "Cell line enhanced" "Detected in many" "Daudi: 22.3;REH: 66.5;SK-MEL-30: 31.2;U-266/70: 61.0;U-266/84: 30.0" "Region enriched" "Detected in all" 6 "basal ganglia: 1277.2" HPA057790 Supported Supported NA NA 72000 "Cluster 43: B-cells - Humoral immune response" "Cluster 65: Brain - Ion transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA057790: AB_2683527" "unprognostic (3.97e-3)" "unprognostic (1.16e-4)" "unprognostic (4.92e-2)" "unprognostic (2.72e-1)" "unprognostic (2.79e-1)" "unprognostic (8.42e-4)" "prognostic favorable (3.05e-4)" "prognostic favorable (1.35e-5)" "unprognostic (1.27e-2)" "unprognostic (4.95e-2)" "prognostic favorable (3.71e-4)" "unprognostic (1.27e-1)" "prognostic favorable (0.00e+0)" "unprognostic (6.96e-2)" "unprognostic (1.46e-1)" "unprognostic (6.36e-2)" "unprognostic (4.96e-2)" 3.5 5.7 70.8 5.3 360.9 6.6 4.4 83.9 127.9 5.5 14.0 6.7 5.2 7.2 5.1 12.0 8.2 3.5 26.4 70.1 66.0 10.5 4.2 4.0 9.9 97.2 87.9 12.2 8.0 6.2 17.4 1.4 76.8 9.5 3.1 15.1 26.0 5.7 3.4 2.6 14.2 3.5 76.0 19.4 6.8 8.9 154.1 2.7 5.8 8.1 9.4 7.9 3.3 81.4 0.2 0.0 3.2 7.1 0.0 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.7 22.3 1.0 0.3 0.3 0.2 3.5 0.0 0.1 0.0 3.1 0.6 0.1 2.7 1.6 0.0 12.9 0.4 0.5 0.0 0.2 0.2 0.0 2.7 0.3 14.2 0.0 2.2 0.6 1.4 2.6 0.4 1.4 66.5 0.0 6.2 0.3 0.0 0.1 9.2 0.1 0.1 31.2 2.1 0.4 5.6 0.1 0.1 3.0 0.2 0.2 61.0 30.0 4.7 0.2 7.0 16.5 3.5 1.5 8.0 0.4 0.5 1.1 57.2 0.5 0.4 6.0 50.1 1.2 0.7 11.8 0.2 0.1 48.0 0.0 3.0 70.8 360.9 83.9 127.9 70.1 66.0 97.2 87.9 76.8 76.0 154.1 81.4 14.5 6.4 4.2 40.8 145.4 2.5 13.0 0.3 5.2 10.5 22.9 30.1 55.1 15.7 3.3 9.2 8.4 0.6 56.1 0.9 123.3 17.0 5.4 2.1 2.3 11.7 6.1 8.6 26.5 4.8 1.1 6.6 5.6 3.5 12.7 8.6 19.2 11.4 63.2 169.9 38.8 2.0 0.0 8.5 15.0 11.4 2.5 12.3 51.6 45.9 11.2 84.7 3.1 102.5 206.1 2.7 1.8 2.6 169.7 7.5 0.7 22.6 2.9 11.1 6.6 7.1 5.4 2.7 2.6 1.5 2.0 3.4 6.9 2.1 2.2 7.2 GPC5 ENSG00000179399 "Glypican 5" P78333 13 91398621-92873682 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 23.1;kidney: 7.3;testis: 6.1" "Cell type enriched" "Detected in some" 20 "Astrocytes: 3868.1" "Cancer enhanced" "Detected in some" "glioma: 2.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "CACO-2: 49.9;HeLa: 27.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040152, HPA044081" Enhanced Approved Nucleoplasm,Cytosol "Intracellular and membrane" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 39: CACO-2 - Unknown function" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm Cytosol "HPA040152: AB_2676863, HPA044081: AB_2678801" "unprognostic (4.99e-3)" "unprognostic (2.20e-2)" "unprognostic (1.00e-1)" "unprognostic (9.93e-5)" "prognostic unfavorable (4.37e-4)" "unprognostic (4.46e-1)" "unprognostic (1.93e-1)" "unprognostic (1.80e-2)" "unprognostic (9.49e-3)" "unprognostic (3.52e-2)" "unprognostic (1.21e-5)" "unprognostic (2.19e-2)" "unprognostic (1.82e-6)" "unprognostic (3.03e-2)" "unprognostic (2.43e-1)" "unprognostic (1.11e-1)" "unprognostic (6.69e-3)" 0.1 1.6 10.3 0.3 18.1 0.1 0.0 6.7 9.6 0.0 0.0 0.5 0.1 0.0 0.1 0.0 0.1 0.5 1.1 8.4 12.1 7.3 1.3 3.2 0.2 18.2 13.4 0.4 0.1 0.0 1.7 0.4 20.5 0.1 0.5 0.5 0.1 0.4 0.0 0.1 0.1 0.1 5.7 0.0 0.1 6.1 23.1 0.1 1.1 0.0 0.0 0.0 0.1 4.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 49.9 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.4 0.0 27.4 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.3 0.6 0.0 1.7 0.0 0.8 0.0 0.2 0.0 0.0 1.0 0.1 0.1 0.1 0.0 0.0 3.4 0.1 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.4 0.3 0.0 0.0 0.0 10.3 18.1 6.7 9.6 8.4 12.1 18.2 13.4 20.5 5.7 23.1 4.9 0.0 0.0 2.7 3868.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 1.3 0.0 0.0 0.1 0.0 0.1 64.6 0.0 1.6 0.0 0.0 0.1 0.0 0.0 116.6 0.0 0.0 0.4 0.0 0.1 0.0 7.9 0.0 0.0 0.1 0.0 190.6 0.1 0.0 0.0 0.4 1.0 0.3 0.1 0.0 118.0 0.6 0.0 0.0 127.2 20.9 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.7 0.8 0.3 0.1 0.0 0.0 0.1 0.1 0.5 0.0 0.1 GPR12 "GPCR21, PPP1R84" ENSG00000132975 "G protein-coupled receptor 12" P47775 13 26755200-26760786 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 14.3;retina: 8.4;skin 1: 5.4" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 9.7;Excitatory neurons: 9.5;Hofbauer cells: 17.6;Horizontal cells: 33.7;Inhibitory neurons: 15.7;Skeletal myocytes: 8.1" "Group enriched" "Detected in some" 7 "breast cancer: 0.5;glioma: 0.8;ovarian cancer: 0.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "SCLC-21H: 14.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050972 Uncertain NA NA "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 62: Horizontal cells - Visual perception" "HPA050972: AB_2681295" "unprognostic (2.37e-2)" "unprognostic (9.64e-3)" "unprognostic (3.75e-1)" "unprognostic (3.30e-1)" "unprognostic (1.40e-2)" "unprognostic (4.65e-2)" "unprognostic (1.42e-1)" "unprognostic (7.35e-2)" "unprognostic (5.53e-2)" "unprognostic (3.83e-2)" "unprognostic (2.40e-1)" 0.2 0.0 3.7 0.0 14.3 0.1 1.4 7.6 10.7 0.3 0.0 0.1 0.0 0.0 0.0 0.1 0.7 0.0 0.2 8.1 1.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.7 0.4 0.2 0.0 0.0 8.4 2.9 0.0 0.1 5.4 0.1 0.1 0.1 0.1 0.0 0.1 4.3 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 14.3 7.6 10.7 8.1 1.0 0.0 3.3 0.2 0.1 4.3 2.9 0.4 0.0 0.0 1.6 0.0 0.1 0.2 0.0 0.0 2.8 2.7 2.8 0.6 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.7 9.7 0.0 9.5 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 17.6 33.7 15.7 0.0 0.0 0.0 0.0 0.5 0.0 0.2 3.6 0.0 0.0 1.9 0.0 5.0 0.9 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 3.5 0.0 8.1 0.2 0.1 0.3 0.0 0.1 0.3 0.2 0.0 0.0 0.2 GPRIN2 "KIAA0514, MGC15171" ENSG00000204175 "G protein regulated inducer of neurite outgrowth 2" O60269 10 46549044-46555530 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 10.5;skin 1: 17.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 19.2;Distal enterocytes: 30.4;Exocrine glandular cells: 20.2;Intestinal goblet cells: 30.8;Late spermatids: 20.6;Proximal enterocytes: 21.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "A-431: 10.2;A549: 13.1;SiHa: 3.7;SK-BR-3: 12.0" "Low region specificity" "Detected in many" "HPA038129, HPA070760" Approved Approved "Plasma membrane,Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane, Microtubules" "Cytokinetic bridge, Mitotic spindle" "HPA038129: AB_2675846, HPA070760: " "unprognostic (1.00e-2)" "unprognostic (1.91e-1)" "unprognostic (1.77e-2)" "prognostic unfavorable (8.60e-8)" "unprognostic (5.77e-2)" "prognostic favorable (3.47e-4)" "unprognostic (2.23e-1)" "unprognostic (2.67e-2)" "unprognostic (2.54e-1)" "unprognostic (1.27e-1)" "unprognostic (1.52e-2)" "unprognostic (1.45e-1)" "unprognostic (8.97e-2)" "unprognostic (1.98e-2)" "unprognostic (2.37e-1)" "unprognostic (1.23e-1)" "unprognostic (5.67e-3)" 0.1 0.0 1.7 0.6 1.6 0.0 0.9 5.9 2.1 0.9 0.4 6.2 3.6 0.0 0.0 4.4 0.3 0.2 0.0 0.6 6.7 5.7 0.3 10.5 0.0 5.5 4.9 0.1 5.7 2.1 4.2 0.0 5.7 1.9 3.4 0.1 2.8 1.1 0.1 17.4 8.0 0.1 1.8 0.0 5.1 3.0 9.7 0.0 3.4 0.0 0.5 0.6 2.0 1.0 10.2 13.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.0 0.2 0.0 0.7 0.8 0.1 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 1.9 0.0 0.0 0.0 0.0 1.7 0.3 0.3 0.1 3.7 12.0 0.0 1.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 1.6 5.9 2.1 0.6 6.7 5.5 4.9 5.7 1.8 9.7 1.0 0.0 19.2 3.7 0.0 0.0 1.7 2.8 1.9 2.8 0.3 1.4 1.0 0.2 7.2 2.1 3.7 0.0 0.0 0.0 30.4 0.0 11.3 9.3 0.0 0.0 0.1 6.6 0.0 0.7 20.2 0.0 0.1 3.6 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.9 30.8 0.0 0.0 0.3 20.6 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 12.6 13.1 0.4 0.0 2.1 21.7 4.0 1.8 0.1 0.0 0.0 0.2 2.9 0.8 2.4 6.1 0.0 0.1 0.0 7.3 1.3 GRHL2 "BOM, DFNA28, FLJ13782, TFCP2L3" ENSG00000083307 "Grainyhead like transcription factor 2" Q6ISB3 8 101492439-101669726 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Corneal dystrophy, Deafness, Disease variant, Dwarfism, Ectodermal dysplasia, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 28.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 32.1;Respiratory ciliated cells: 28.8;Squamous epithelial cells: 27.1;Suprabasal keratinocytes: 26.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 39.3;CACO-2: 28.0;HaCaT: 46.3;hTCEpi: 35.5;MCF7: 32.7;OE19: 37.9;RT4: 68.9;T-47d: 79.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA004820, HPA062839" Uncertain Supported Nucleoplasm NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA004820: AB_1857928, HPA062839: AB_2684878" "prognostic unfavorable (6.43e-4)" "unprognostic (2.54e-2)" "unprognostic (4.09e-2)" "unprognostic (2.95e-2)" "unprognostic (2.68e-1)" "unprognostic (4.79e-2)" "unprognostic (1.90e-1)" "unprognostic (2.66e-1)" "unprognostic (1.64e-1)" "unprognostic (8.59e-2)" "prognostic unfavorable (6.27e-4)" "unprognostic (2.61e-2)" "unprognostic (8.29e-4)" "unprognostic (4.54e-3)" "unprognostic (2.64e-1)" "unprognostic (1.08e-1)" "unprognostic (1.03e-2)" 0.1 0.0 0.0 1.0 0.0 0.0 12.3 0.0 0.3 6.9 0.0 8.0 4.0 1.7 16.1 20.4 8.5 3.3 0.0 0.0 0.0 6.3 0.4 5.6 0.0 0.0 0.0 0.0 11.1 9.3 0.8 6.7 0.0 23.2 9.2 0.0 14.8 7.2 0.0 28.6 4.3 0.4 0.0 0.1 9.8 0.3 0.0 2.9 10.2 0.0 4.6 7.7 10.4 0.0 39.3 0.0 0.0 0.0 0.0 0.0 19.5 0.0 0.0 0.0 0.0 28.0 18.9 0.0 0.0 0.1 0.0 46.3 0.0 22.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 35.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.7 0.0 0.3 0.2 37.9 0.0 0.0 0.0 0.1 0.0 68.9 1.9 0.0 0.0 15.0 0.0 4.4 79.7 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 32.1 13.0 0.3 0.0 24.3 10.5 7.6 20.5 0.0 14.4 6.1 0.7 17.2 20.8 11.0 0.0 14.0 0.2 10.3 5.9 7.5 2.4 20.0 1.5 0.8 1.2 0.0 0.8 5.5 7.1 0.8 15.3 20.7 0.0 0.0 0.0 0.0 1.4 0.0 1.3 9.8 2.0 0.0 1.1 9.3 0.0 0.3 1.8 0.0 0.6 0.0 0.0 2.0 0.5 8.8 8.5 0.0 1.3 9.3 5.7 0.1 28.8 0.0 0.0 0.5 1.0 0.1 0.0 27.1 26.0 19.8 0.3 0.1 11.0 6.3 GRIN1 "GluN1, NMDAR1" ENSG00000176884 "Glutamate ionotropic receptor NMDA type subunit 1" Q05586 9 137139154-137168756 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 49 "brain: 186.7" "Group enriched" "Detected in some" 4 "Excitatory neurons: 132.6;Inhibitory neurons: 134.4" "Cancer enhanced" "Detected in some" "glioma: 1.9;prostate cancer: 1.8" "Region enriched" "Detected in many" 4 "cerebral cortex: 186.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "OE19: 1.4;REH: 1.9;RPMI-8226: 2.5;SCLC-21H: 5.2;SH-SY5Y: 3.1;T-47d: 1.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067773 Enhanced NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA067773: " "unprognostic (3.58e-2)" "unprognostic (4.51e-1)" "unprognostic (2.68e-2)" "unprognostic (5.48e-4)" "unprognostic (5.20e-2)" "unprognostic (1.25e-1)" "unprognostic (2.34e-2)" "unprognostic (2.81e-2)" "unprognostic (6.46e-3)" "unprognostic (1.51e-1)" "unprognostic (1.69e-1)" "unprognostic (1.78e-1)" "unprognostic (1.21e-3)" "unprognostic (4.47e-2)" "unprognostic (1.44e-1)" "unprognostic (3.56e-3)" "unprognostic (4.72e-2)" 0.0 0.1 15.7 0.2 46.4 0.0 0.2 0.0 186.7 0.0 0.0 0.8 0.4 0.0 0.0 0.1 0.0 0.0 0.1 35.9 0.0 0.0 0.0 0.1 0.1 1.3 19.5 0.0 0.1 0.2 0.7 0.0 3.8 0.7 0.0 3.7 1.2 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 35.6 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.8 0.1 0.0 0.2 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.5 0.0 0.0 0.0 1.4 0.0 1.9 0.0 2.5 0.0 0.0 5.2 3.1 0.1 0.3 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.7 46.4 0.0 186.7 35.9 0.0 1.3 19.5 3.8 0.0 0.0 35.6 0.0 0.0 0.0 8.5 0.0 0.0 0.3 0.1 0.0 28.0 1.2 0.9 2.5 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.3 1.9 0.2 0.1 0.2 1.8 0.0 132.6 0.4 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.1 1.7 134.4 1.8 0.0 0.0 0.0 0.6 0.0 0.2 0.0 9.4 2.0 1.7 0.0 10.1 7.6 0.2 0.1 0.0 0.0 0.7 0.5 0.1 0.3 7.8 0.0 0.0 0.1 0.5 2.1 0.0 0.0 0.0 0.0 0.0 0.1 0.4 GRIP1 ENSG00000155974 "Glutamate receptor interacting protein 1" Q9Y3R0 12 66347431-67069162 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 16.4" "Cell type enriched" "Detected in many" 7 "Inhibitory neurons: 2829.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 5 "myeloid DC: 4.9" "Lineage enriched" "Detected in many" 5 "dendritic cells: 4.9" "Cell line enhanced" "Detected in many" "BEWO: 44.4;HaCaT: 48.7;REH: 30.7;RT4: 31.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038856 Uncertain NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA038856: AB_10673297" "unprognostic (6.25e-3)" "unprognostic (6.41e-2)" "unprognostic (1.52e-2)" "unprognostic (8.25e-2)" "unprognostic (1.50e-1)" "unprognostic (5.12e-2)" "unprognostic (2.42e-1)" "unprognostic (4.21e-3)" "unprognostic (4.25e-1)" "unprognostic (1.60e-2)" "unprognostic (1.00e-2)" "unprognostic (4.14e-1)" "unprognostic (2.82e-3)" "unprognostic (7.44e-2)" "unprognostic (1.32e-1)" "unprognostic (7.27e-4)" "unprognostic (8.57e-3)" 0.5 4.3 8.5 2.7 6.6 0.5 3.0 0.0 14.2 1.2 0.0 3.1 1.1 3.5 4.7 7.3 4.2 1.6 2.7 3.9 12.4 3.3 0.3 0.8 0.7 0.7 7.6 1.2 2.0 16.4 3.3 8.2 2.2 4.6 1.7 4.8 6.0 9.3 1.0 9.8 1.9 2.8 0.0 2.6 0.8 6.2 3.0 0.7 5.0 0.6 1.3 2.6 2.0 3.7 11.1 10.1 17.7 2.1 0.0 0.0 44.4 3.2 0.0 5.4 2.5 0.3 3.3 1.4 4.2 0.0 9.5 48.7 4.9 3.3 2.4 0.0 12.0 0.0 0.1 0.3 0.0 1.2 0.1 0.0 8.0 0.0 0.8 8.3 0.0 8.0 0.0 0.1 0.0 4.0 0.4 0.4 16.1 1.4 3.6 30.7 0.1 0.6 5.6 31.0 10.8 1.4 14.8 7.1 1.4 11.3 8.7 1.8 0.0 0.0 12.7 0.1 9.0 1.5 0.3 1.0 12.0 0.7 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.9 0.1 0.1 0.2 0.0 1.0 0.0 0.3 0.0 0.1 8.5 6.6 0.0 14.2 3.9 12.4 0.7 7.6 2.2 0.0 3.0 3.7 0.1 0.0 1.1 74.7 0.1 13.3 2.3 2.9 2.2 5.5 4.1 2.4 3.4 1.5 1.7 7.3 0.0 7.8 0.7 0.3 0.0 2.2 38.5 8.1 2.2 0.4 1.8 0.0 390.2 1.5 4.3 1.1 0.0 13.7 0.0 2.3 0.0 0.0 1.0 47.1 2829.7 0.7 0.0 2.4 1.6 34.0 0.6 2.1 7.2 20.6 1.0 0.5 0.0 158.3 44.4 1.9 0.5 0.7 0.1 3.8 0.2 0.4 1.1 1.8 0.0 1.0 0.6 0.3 1.2 2.3 17.8 16.6 0.8 1.2 0.7 3.1 GRTP1 "FLJ22474, TBC1D6" ENSG00000139835 "Growth hormone regulated TBC protein 1" Q5TC63 13 113324163-113364148 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 83.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 81.3;Proximal enterocytes: 70.2;Rod photoreceptor cells: 69.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 2.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "OE19: 60.4;T-47d: 54.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046201 Enhanced NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 6: T47d - Mammary gland" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA046201: AB_2679584" "unprognostic (5.31e-2)" "unprognostic (2.27e-3)" "unprognostic (1.94e-1)" "unprognostic (1.89e-1)" "unprognostic (4.42e-2)" "unprognostic (1.49e-1)" "unprognostic (1.57e-1)" "unprognostic (1.27e-1)" "unprognostic (1.75e-1)" "unprognostic (6.05e-2)" "unprognostic (1.30e-2)" "unprognostic (3.07e-3)" "prognostic favorable (1.50e-5)" "unprognostic (4.41e-3)" "unprognostic (5.55e-2)" "unprognostic (8.56e-2)" "unprognostic (4.50e-3)" 4.4 14.2 2.6 3.2 2.6 2.9 7.9 3.5 5.3 14.3 5.8 24.8 46.0 8.6 3.5 21.6 10.5 6.1 2.6 2.7 2.0 19.3 83.9 4.5 1.6 2.8 2.8 12.8 9.8 8.3 2.8 2.9 2.5 18.3 13.3 20.9 14.5 4.9 10.0 25.9 38.8 3.0 2.8 7.8 13.2 9.5 2.7 1.6 4.0 1.3 2.5 10.6 17.0 3.2 10.1 3.8 7.5 12.9 1.2 1.9 23.6 1.9 0.0 0.5 0.2 21.9 23.2 0.6 1.5 0.6 4.7 15.5 6.6 1.9 0.0 0.5 8.7 13.5 11.2 21.9 2.1 1.1 4.8 0.6 2.9 1.6 0.2 1.0 0.0 1.3 8.2 0.7 0.0 20.5 0.2 1.9 21.2 60.4 2.9 1.1 0.3 0.4 1.7 12.3 0.6 6.6 0.4 11.3 2.7 8.9 54.6 1.3 1.0 0.4 2.8 1.8 0.7 3.8 4.3 1.5 8.1 3.0 4.4 0.6 0.4 0.3 0.2 0.2 0.2 0.2 0.3 0.2 0.1 0.3 0.5 0.2 2.2 0.3 0.5 0.3 0.1 0.7 2.6 2.6 3.5 5.3 2.7 2.0 2.8 2.8 2.5 2.8 2.7 3.2 1.1 0.0 6.0 11.1 0.8 21.7 24.0 23.4 14.2 5.8 12.7 8.6 1.2 30.0 15.9 3.7 81.3 28.8 0.7 51.8 23.5 10.0 0.4 6.2 4.8 3.0 3.6 3.8 0.5 9.2 9.2 4.0 14.3 8.8 0.0 18.3 5.7 30.1 1.7 3.3 0.5 28.2 16.2 0.8 1.9 0.8 8.1 2.3 1.8 1.0 2.6 13.7 0.0 1.0 1.0 9.6 43.3 8.6 0.1 11.0 70.2 45.8 9.6 69.6 0.0 5.9 5.3 0.2 8.8 18.2 23.7 25.3 1.2 2.7 40.1 23.8 GSDMC MLZE ENSG00000147697 "Gasdermin C" Q9BYG8 8 129748196-129786624 "Predicted intracellular proteins, Transporters" Necrosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 33.1;lymphoid tissue: 12.8;skin 1: 25.5;vagina: 11.4" "Group enriched" "Detected in some" 4 "Basal keratinocytes: 46.5;Basal squamous epithelial cells: 37.5;Squamous epithelial cells: 29.5;Suprabasal keratinocytes: 53.1" "Cancer enhanced" "Detected in many" "cervical cancer: 11.8;head and neck cancer: 19.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 5.2;HaCaT: 3.7;hTCEpi: 1.8;HUVEC TERT2: 2.0;TIME: 5.8" "Low region specificity" "Detected in many" "HPA023670, HPA024767, HPA026317" Supported Approved Mitochondria NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" Mitochondria "HPA023670: AB_1854006, HPA024767: AB_1854007, HPA026317: AB_1854008" "unprognostic (6.33e-3)" "unprognostic (1.49e-1)" "unprognostic (2.61e-3)" "unprognostic (4.23e-2)" "unprognostic (2.11e-2)" "unprognostic (4.22e-3)" "unprognostic (1.43e-2)" "unprognostic (1.15e-1)" "unprognostic (8.28e-2)" "unprognostic (7.51e-2)" "unprognostic (4.92e-3)" "unprognostic (5.71e-2)" "unprognostic (2.93e-3)" "unprognostic (1.87e-2)" "unprognostic (1.88e-1)" "unprognostic (8.66e-2)" "unprognostic (1.90e-1)" 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 4.4 0.0 0.0 0.0 0.0 0.1 33.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 5.4 0.0 0.0 25.5 0.0 0.0 0.0 12.8 0.0 0.0 0.0 0.0 0.0 0.0 4.0 2.4 11.4 0.1 5.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 3.7 0.0 0.6 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.1 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 2.0 1.0 0.0 46.5 0.9 7.4 37.5 0.0 1.5 0.9 3.6 0.0 9.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.2 0.2 0.0 0.9 0.0 0.0 0.1 0.2 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 6.1 0.0 3.9 0.0 0.0 0.2 7.2 0.0 0.0 0.0 0.0 0.0 0.1 1.4 0.0 0.0 0.0 0.4 0.0 0.0 1.3 0.0 0.0 0.1 0.5 0.0 0.1 29.5 53.1 0.0 0.1 0.0 0.0 2.8 GSN DKFZp313L0718 ENSG00000148180 Gelsolin P06396 9 121207794-121332843 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cilium biogenesis/degradation" "Actin capping, Actin-binding" "Amyloidosis, Cancer-related genes, Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 2486.9" "Cell type enhanced" "Detected in all" "Adipocytes: 1649.5;Fibroblasts: 4145.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 1135.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 1313.9;HaCaT: 533.6" "Region enriched" "Detected in all" 4 "white matter: 869.2" "Low region specificity" "Detected in all" "CAB010823, CAB016728, CAB036009, HPA054026" Supported Supported "Actin filaments" "Secreted to blood" NA NA 112000000000 240000000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Actin filaments" "CAB010823: , CAB016728: , CAB036009: , HPA054026: AB_2682347" "unprognostic (3.25e-2)" "unprognostic (4.44e-3)" "unprognostic (1.22e-1)" "unprognostic (3.10e-3)" "unprognostic (4.23e-2)" "unprognostic (4.85e-2)" "unprognostic (1.21e-1)" "unprognostic (1.49e-1)" "unprognostic (1.22e-1)" "unprognostic (1.20e-1)" "unprognostic (6.54e-2)" "unprognostic (6.56e-2)" "unprognostic (3.06e-2)" "unprognostic (8.01e-3)" "unprognostic (4.98e-2)" "unprognostic (1.23e-2)" "prognostic unfavorable (1.79e-5)" 1892.9 162.5 169.7 109.7 317.4 175.0 1244.6 291.2 213.0 577.4 155.6 867.4 152.0 767.7 108.2 435.1 663.2 226.1 2486.9 163.4 219.8 153.1 40.6 308.7 93.2 380.9 284.6 303.8 140.7 70.9 260.6 79.0 354.7 344.0 204.6 57.8 508.7 400.9 420.4 612.9 384.1 350.0 270.6 136.5 469.7 78.1 279.0 99.7 702.6 687.8 87.3 897.2 655.5 376.1 38.4 60.9 39.0 129.8 1313.9 351.8 26.4 130.9 264.7 30.1 56.5 64.2 130.1 3.0 36.6 182.8 48.5 533.6 3.2 84.3 16.9 6.5 7.6 31.2 57.1 167.5 32.0 7.0 146.0 140.0 84.9 51.7 34.4 83.1 120.4 6.1 10.4 5.3 137.0 81.1 0.4 304.4 12.7 76.2 45.1 8.4 13.1 4.3 156.4 63.4 7.7 10.4 60.9 62.5 197.2 84.6 245.3 158.8 217.4 100.0 33.2 10.4 12.8 1.8 2.0 3.2 105.3 18.2 278.1 302.9 122.0 1135.9 1.9 84.9 0.8 17.6 0.8 1.4 345.3 6.7 0.8 0.7 307.1 217.8 23.7 243.2 4.2 105.4 169.7 317.4 291.2 213.0 163.4 219.8 380.9 284.6 354.7 270.6 279.0 376.1 1649.5 147.4 55.7 82.3 22.7 341.2 278.1 252.7 103.0 7.5 120.8 212.0 272.0 85.8 354.3 121.4 77.2 55.8 74.9 557.7 105.7 258.5 9.9 141.9 163.1 724.8 63.1 17.2 17.1 202.3 94.3 4145.2 322.7 220.6 104.0 31.8 273.5 16.5 492.6 1.7 9.0 762.9 512.7 139.0 798.7 20.2 588.7 273.7 537.2 155.5 487.5 220.6 55.6 33.2 443.1 315.8 590.5 671.8 24.1 91.4 77.4 39.8 583.7 86.5 611.4 362.4 740.4 8.7 13.7 175.9 299.1 84.0 58.7 34.3 52.2 144.7 GSTA3 ENSG00000174156 "Glutathione S-transferase alpha 3" Q16772 6 52896639-52909698 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "adrenal gland: 67.3;fallopian tube: 65.4;placenta: 22.7;skin 1: 26.0" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 194.9;Syncytiotrophoblasts: 515.3;Theca cells: 91.3" "Cancer enhanced" "Detected in some" "endometrial cancer: 1.5;testis cancer: 1.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SuSa: 1.4" "HPA004342, HPA048934, HPA053817" Approved Supported Cytosol NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "HPA004342: AB_1078987, HPA048934: AB_2680563, HPA053817: AB_2630367" "unprognostic (7.51e-2)" "unprognostic (7.06e-3)" "unprognostic (3.10e-1)" "unprognostic (5.53e-2)" "unprognostic (4.38e-3)" "unprognostic (2.86e-3)" "unprognostic (1.81e-1)" "unprognostic (1.41e-1)" "unprognostic (1.93e-1)" "unprognostic (9.35e-2)" 0.0 67.3 0.0 0.1 0.1 0.0 1.8 0.0 0.0 1.1 0.5 0.0 0.3 0.8 0.8 0.0 65.4 0.0 0.0 0.0 0.2 0.0 0.0 1.4 0.0 0.1 0.5 0.9 0.1 2.9 0.0 22.7 0.0 0.1 0.0 0.0 0.3 0.2 0.0 26.0 0.4 0.1 0.0 0.0 2.4 11.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.5 0.0 0.0 0.3 0.1 0.0 0.0 1.1 0.0 0.0 1.0 0.0 0.9 0.0 0.0 0.4 0.0 0.0 0.0 6.2 0.0 0.0 194.9 0.0 0.0 0.0 0.0 1.3 47.0 0.5 0.5 0.0 0.0 0.0 0.0 7.5 1.1 0.0 0.7 1.3 7.4 0.0 0.4 15.7 0.0 0.0 0.0 2.0 0.0 0.4 2.1 1.5 0.0 24.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.4 24.8 0.0 0.0 0.0 0.8 0.5 0.5 0.0 9.8 515.3 0.1 91.3 0.0 0.0 GSX2 Gsh2 ENSG00000180613 "GS homeobox 2" Q9BZM3 4 54099523-54102498 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant, Dystonia, Mental retardation" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 1.2" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 15 "glioma: 2.6" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "basal ganglia: 1.2" "Not detected" "Not detected" NA NA "Cluster 65: Brain - Ion transport" "Cluster 43: Cardiomyocytes - Nuclear processes" "unprognostic (4.48e-2)" "unprognostic (1.05e-1)" "unprognostic (7.01e-2)" "unprognostic (1.89e-1)" 0.0 0.0 0.8 0.0 1.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.2 0.0 0.6 0.2 0.2 0.2 0.2 0.4 0.3 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GTF3C1 TFIIIC220 ENSG00000077235 "General transcription factor IIIC subunit 1" Q12789 16 27459555-27549913 "Predicted intracellular proteins, Predicted membrane proteins" Transcription DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 93.8;dendritic cells: 86.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "gdT-cell: 31.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051617, HPA075900" Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 72: Non-specific - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Nucleoli" "HPA051617: AB_2681553, HPA075900: " "unprognostic (6.46e-2)" "unprognostic (6.86e-3)" "unprognostic (2.16e-1)" "unprognostic (5.59e-2)" "unprognostic (6.65e-2)" "unprognostic (2.90e-2)" "prognostic unfavorable (8.73e-4)" "unprognostic (8.23e-2)" "unprognostic (9.25e-3)" "unprognostic (5.32e-2)" "prognostic favorable (9.56e-4)" "unprognostic (2.10e-1)" "prognostic favorable (1.25e-4)" "unprognostic (2.06e-1)" "unprognostic (5.67e-2)" "unprognostic (5.56e-3)" "unprognostic (8.23e-3)" 18.1 28.8 24.2 9.9 24.4 16.6 16.7 21.5 32.6 31.2 40.5 21.2 8.8 26.7 7.8 65.2 24.6 11.5 38.5 24.6 21.8 25.4 21.7 20.3 12.2 20.4 20.8 24.4 35.3 18.6 47.8 11.0 19.6 40.4 9.7 18.3 24.9 12.6 50.2 51.0 18.5 15.5 17.0 21.3 24.7 26.6 22.2 18.6 34.6 20.8 11.2 19.7 35.1 21.7 27.8 60.1 43.3 50.7 37.8 30.4 24.6 29.5 33.0 40.2 34.0 45.0 25.6 30.5 42.3 36.4 30.6 30.3 55.4 37.6 32.9 13.7 53.1 25.2 49.8 63.8 21.3 29.1 32.2 37.5 28.0 49.5 21.8 26.9 40.2 34.6 31.7 24.2 32.0 67.6 32.5 34.8 58.4 15.1 28.3 59.7 53.4 31.4 25.2 28.7 54.4 36.5 29.8 24.9 18.6 34.4 44.8 21.8 43.2 40.2 24.0 25.6 30.7 25.6 24.8 30.2 16.6 31.7 30.2 2.6 3.4 3.5 31.9 3.2 23.0 3.1 3.6 15.8 4.3 2.2 3.7 10.0 2.5 12.2 3.3 6.6 4.0 6.9 24.2 24.4 21.5 32.6 24.6 21.8 20.4 20.8 19.6 17.0 22.2 21.7 16.9 19.2 23.9 29.7 10.8 18.4 7.3 14.3 23.3 45.5 10.6 11.9 27.4 10.0 17.2 12.9 93.8 7.8 86.2 18.4 5.9 11.8 2.8 40.4 37.3 18.0 30.0 7.2 30.2 11.5 4.3 22.5 19.9 22.3 19.0 26.1 13.9 13.7 10.9 26.9 33.9 17.6 18.3 10.3 7.7 4.5 19.3 12.9 3.6 14.0 10.0 15.0 52.5 17.1 23.4 15.8 9.3 15.8 29.6 13.9 10.2 9.0 30.8 35.1 13.1 16.4 15.1 17.2 18.2 34.8 20.6 4.2 32.7 25.7 12.2 6.7 HACL1 "2-HPCL, HPCL, PHYH2" ENSG00000131373 "2-hydroxyacyl-CoA lyase 1" Q9UJ83 3 15560699-15601852 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "basophil: 117.3" "Lineage enriched" "Detected in all" 5 "granulocytes: 117.3" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035496, HPA035497, HPA073760" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 38: Basophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles Nucleoplasm "HPA035496: AB_10601328, HPA035497: AB_2674653, HPA073760: AB_2686633" "unprognostic (6.64e-3)" "unprognostic (2.82e-2)" "unprognostic (2.24e-3)" "unprognostic (3.82e-1)" "unprognostic (4.08e-2)" "unprognostic (1.77e-1)" "unprognostic (2.96e-2)" "unprognostic (6.31e-2)" "unprognostic (8.27e-3)" "unprognostic (5.23e-2)" "unprognostic (3.30e-2)" "unprognostic (1.44e-1)" "prognostic favorable (2.63e-5)" "unprognostic (6.62e-2)" "unprognostic (2.66e-1)" "unprognostic (3.23e-2)" "unprognostic (9.07e-2)" 14.4 12.0 7.5 8.2 7.8 11.6 14.6 10.4 10.5 9.1 7.9 10.0 56.6 8.3 16.6 7.5 10.8 8.8 11.0 7.6 7.0 26.0 51.8 9.7 14.1 7.4 7.2 7.5 15.2 20.0 7.8 7.8 7.0 10.8 12.0 12.2 9.1 9.1 17.6 10.6 27.7 9.5 7.4 11.4 13.2 26.7 6.8 13.9 20.4 10.6 14.5 10.3 6.4 10.0 15.1 28.6 8.2 30.7 13.4 12.4 82.3 14.2 22.0 26.6 26.3 27.3 14.3 14.6 9.7 18.7 10.5 10.4 18.7 25.3 23.8 13.6 36.4 25.4 17.7 24.7 20.3 30.5 23.1 13.7 16.2 37.9 16.6 8.3 31.4 18.3 24.0 21.2 22.9 28.7 14.0 12.6 19.7 19.7 29.7 14.4 21.5 19.6 26.4 20.2 9.6 12.3 22.4 19.0 25.2 12.8 8.5 25.4 22.5 14.1 14.6 17.4 24.7 27.2 50.9 28.5 27.1 26.4 17.2 117.3 16.0 18.3 14.4 20.1 21.2 15.4 15.5 18.0 16.0 21.2 14.8 16.1 3.4 24.1 24.2 10.2 19.8 13.0 7.5 7.8 10.4 10.5 7.6 7.0 7.4 7.2 7.0 7.4 6.8 10.0 12.4 9.6 17.3 34.9 22.1 10.3 12.0 13.5 20.5 19.3 9.1 10.2 6.4 14.3 15.6 11.0 29.2 27.2 15.7 6.1 13.7 16.0 66.6 12.6 6.0 12.3 9.1 8.2 67.4 25.2 18.0 12.0 11.2 5.4 13.3 12.7 8.9 24.3 13.2 13.5 55.8 7.5 10.2 9.3 8.1 56.8 23.3 8.8 12.4 25.3 19.3 24.8 8.2 40.7 38.8 14.5 11.2 15.4 21.4 9.0 41.9 39.7 29.8 38.3 6.6 9.0 11.2 51.1 24.4 8.6 7.1 18.9 19.4 15.1 10.6 7.9 HCAR3 "GPR109B, HCA3, HM74" ENSG00000255398 "Hydroxycarboxylic acid receptor 3" P49019 12 122714756-122716811 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 27.4;esophagus: 16.8;lymphoid tissue: 19.6;skin 1: 17.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 94.4;Basal prostatic cells: 81.1;Basal respiratory cells: 57.3;Basal squamous epithelial cells: 159.4;Langerhans cells: 57.4;Squamous epithelial cells: 66.9;Suprabasal keratinocytes: 106.3;Urothelial cells: 66.1" "Group enriched" "Detected in some" 4 "cervical cancer: 2.1;head and neck cancer: 2.5;lung cancer: 1.0;urothelial cancer: 1.9" "Region enriched" "Detected in single" 5 "cerebral cortex: 4.7" "Group enriched" "Detected in many" 6 "basophil: 58.6;neutrophil: 177.2;non-classical monocyte: 84.4" "Group enriched" "Detected in many" 50 "granulocytes: 177.2;monocytes: 84.4" "Cell line enriched" "Detected in some" 4 "RT4: 37.1" HPA028660 Approved Approved "Cell Junctions" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 15: RT4 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" "Cell Junctions" "HPA028660: AB_10602139" "unprognostic (2.32e-1)" "unprognostic (5.82e-2)" "unprognostic (8.23e-2)" "unprognostic (2.27e-1)" "unprognostic (1.17e-1)" "unprognostic (9.17e-2)" "unprognostic (1.64e-3)" "unprognostic (1.60e-1)" "unprognostic (6.29e-2)" "unprognostic (9.87e-2)" "unprognostic (1.50e-2)" "unprognostic (2.80e-1)" "unprognostic (1.23e-1)" "unprognostic (2.30e-2)" "unprognostic (2.83e-1)" "unprognostic (1.16e-1)" "unprognostic (9.28e-2)" 5.6 0.1 0.0 9.2 0.1 27.4 2.3 0.0 4.7 2.5 0.2 0.5 0.2 0.0 0.5 16.8 0.7 0.6 0.7 0.1 0.0 0.9 1.8 8.2 0.4 0.0 0.0 0.1 0.0 3.4 0.2 1.9 0.9 1.5 0.1 0.1 3.4 2.7 0.1 17.4 0.2 0.2 0.0 19.6 0.4 0.1 0.1 4.0 0.4 1.1 7.8 7.1 4.3 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 9.2 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.2 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 37.1 0.2 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.4 0.0 0.0 0.0 0.1 58.6 2.2 0.8 0.0 16.7 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.1 177.2 0.0 84.4 0.0 0.0 2.9 0.0 0.1 0.0 4.7 0.1 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.1 3.2 6.7 0.0 0.7 94.4 81.1 57.3 159.4 0.2 0.7 0.3 0.0 0.0 24.6 0.0 0.0 1.3 0.2 0.0 0.0 0.0 0.7 0.0 0.0 1.0 0.0 0.0 0.0 0.0 21.5 1.4 0.0 0.1 3.8 0.0 0.0 0.1 6.0 0.0 0.0 0.0 12.2 10.6 57.4 0.2 0.0 20.1 8.8 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 14.7 0.0 0.1 2.2 0.2 0.0 0.0 1.4 0.1 0.0 66.9 106.3 13.8 1.0 0.0 0.0 66.1 HCLS1 "CTTNL, HS1" ENSG00000180353 "Hematopoietic cell-specific Lyn substrate 1" P14317 3 121631399-121660927 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 153.6;lymphoid tissue: 300.3" "Cell type enhanced" "Detected in many" "B-cells: 175.7;Kupffer cells: 666.3;Macrophages: 269.0;monocytes: 245.7;NK-cells: 216.3;T-cells: 181.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 265.6;HMC-1: 362.3;RPMI-8226: 256.5;THP-1: 262.8;U-266/70: 361.6;U-698: 371.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019143 Enhanced Supported "Plasma membrane,Cytosol" NA NA 870000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Cytosol" "HPA019143: AB_1850532" "unprognostic (2.27e-2)" "unprognostic (1.79e-3)" "unprognostic (5.38e-3)" "unprognostic (6.29e-2)" "unprognostic (1.01e-2)" "unprognostic (4.02e-3)" "unprognostic (2.35e-1)" "unprognostic (4.88e-3)" "unprognostic (1.70e-2)" "unprognostic (1.19e-1)" "unprognostic (6.76e-2)" "unprognostic (2.28e-1)" "unprognostic (1.03e-3)" "unprognostic (2.93e-1)" "unprognostic (3.46e-2)" "unprognostic (2.60e-2)" "unprognostic (2.01e-1)" 67.0 32.9 14.6 147.2 14.7 153.6 25.5 15.4 18.7 20.7 15.8 29.2 21.2 13.7 6.4 15.7 21.5 37.8 18.4 14.3 17.0 21.5 39.1 52.7 207.6 21.6 17.5 9.4 11.9 7.7 14.6 51.4 20.8 15.8 31.4 2.3 16.0 11.1 7.3 11.1 68.7 34.6 18.5 300.3 27.1 4.5 18.2 140.3 15.4 18.8 242.8 53.0 13.7 23.0 0.8 0.0 0.2 0.1 20.9 11.5 5.7 4.1 4.0 0.8 1.6 0.1 0.0 265.6 124.6 0.0 0.2 0.3 6.9 9.9 1.1 120.6 0.0 172.6 0.0 0.0 11.6 192.4 362.3 2.2 0.5 0.0 1.5 0.0 153.4 106.2 35.1 235.9 0.0 0.0 137.9 162.9 0.3 0.2 4.5 137.1 0.2 256.5 0.0 68.0 0.3 0.2 0.2 0.4 0.6 0.6 0.1 262.8 203.5 0.0 2.0 0.3 0.9 361.6 118.1 371.5 1.9 181.5 0.2 357.3 713.1 1180.9 405.3 870.4 333.0 345.7 334.2 376.8 636.2 313.1 279.3 326.2 1619.2 280.0 997.1 197.4 494.2 1427.9 14.6 14.7 15.4 18.7 14.3 17.0 21.6 17.5 20.8 18.5 18.2 23.0 23.0 9.6 31.8 1.0 175.7 3.2 1.0 7.8 0.6 0.5 2.7 5.1 2.3 4.3 13.1 0.0 0.0 122.4 139.5 0.8 0.0 0.3 1.1 8.8 1.6 23.3 0.0 50.5 1.4 0.2 60.0 7.0 8.6 3.1 73.4 0.7 27.8 7.7 126.9 0.0 0.7 0.4 4.1 666.3 105.8 1.5 3.4 269.0 19.6 26.2 245.7 0.4 216.3 0.5 0.3 0.2 0.2 1.2 148.6 0.4 0.1 0.9 24.7 0.8 13.1 3.7 6.7 0.6 0.6 1.3 4.4 145.4 181.4 2.4 0.5 2.2 HEATR4 MGC48595 ENSG00000187105 "HEAT repeat containing 4" Q86WZ0 14 73478484-73558947 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.4;testis: 11.5" "Cell type enhanced" "Detected in some" "Astrocytes: 27.4;Early spermatids: 85.5;Excitatory neurons: 19.8;Inhibitory neurons: 16.9;Late spermatids: 29.3;Oligodendrocyte precursor cells: 13.0" "Not detected" "Not detected" "Region enriched" "Detected in some" 6 "cerebellum: 6.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MCF7: 2.2;SCLC-21H: 2.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA003642, HPA079348" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 21: Non-specific - Transcription" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 23: Spermatids - Flagellum & Golgi organization" Vesicles Cytosol "HPA003642: AB_1079376, HPA079348: " "unprognostic (5.25e-2)" "unprognostic (2.45e-3)" "unprognostic (2.85e-2)" "unprognostic (1.36e-2)" "unprognostic (2.53e-2)" "unprognostic (2.60e-2)" "unprognostic (3.50e-1)" "unprognostic (8.09e-2)" "unprognostic (3.13e-1)" "unprognostic (1.51e-1)" "unprognostic (4.49e-2)" "unprognostic (1.39e-1)" "unprognostic (1.02e-1)" "unprognostic (3.28e-1)" "unprognostic (5.50e-2)" "unprognostic (1.96e-1)" "unprognostic (4.82e-3)" 0.5 0.5 0.2 0.8 0.2 0.9 0.4 6.4 1.0 0.7 0.0 0.4 1.9 1.0 0.3 0.6 0.6 0.8 0.6 0.8 0.0 0.4 0.8 0.5 1.6 0.0 0.0 1.0 0.9 0.2 0.5 0.3 0.1 0.4 0.1 2.9 0.8 0.1 1.9 3.6 0.8 0.1 0.0 1.0 0.7 11.5 0.1 0.0 1.0 0.0 0.0 0.3 0.5 0.8 0.7 0.8 0.3 0.5 0.0 0.0 0.3 0.3 0.0 0.0 0.1 0.2 0.2 0.8 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.2 0.1 0.6 0.1 0.0 0.0 0.5 1.0 0.0 0.0 0.1 0.0 0.5 0.0 0.8 0.2 0.2 0.0 2.2 0.2 0.9 0.3 0.2 0.7 0.4 0.4 0.3 0.0 1.1 2.4 0.3 0.8 1.1 1.2 0.5 1.3 0.1 0.4 0.1 0.9 0.7 0.1 0.6 0.2 0.1 0.5 0.2 0.1 0.2 0.1 0.1 0.4 0.1 0.2 0.5 0.5 0.3 0.0 0.6 0.5 0.5 0.3 0.3 0.0 0.2 0.2 0.1 0.2 0.2 6.4 1.0 0.8 0.0 0.0 0.0 0.1 0.0 0.1 0.8 0.2 0.0 1.5 27.4 0.2 0.3 0.5 0.1 0.0 0.8 0.3 0.3 0.8 0.0 0.0 0.0 0.0 0.3 0.1 0.2 0.0 0.0 85.5 0.3 0.3 0.4 0.0 0.0 19.8 0.0 0.2 0.5 0.0 0.9 0.0 0.4 0.0 0.6 0.1 0.0 16.9 0.2 0.0 0.0 1.0 29.3 0.6 0.3 0.0 3.7 0.0 0.6 0.0 13.0 6.8 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.7 0.1 0.0 0.9 0.7 11.1 1.6 0.0 0.9 0.1 0.4 0.1 0.0 0.1 HEPACAM "FLJ25530, GLIALCAM" ENSG00000165478 "Hepatic and glial cell adhesion molecule" Q14CZ8 11 124919205-124936412 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cell adhesion, Cell cycle, Growth arrest, Growth regulation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 222.6;choroid plexus: 79.7" "Group enriched" "Detected in some" 9 "Astrocytes: 184.8;Oligodendrocyte precursor cells: 72.9;Oligodendrocytes: 163.2" "Cancer enriched" "Detected in some" 12 "glioma: 29.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 30 "Hep G2: 25.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017613, CAB025486" Enhanced Approved Vesicles NA NA "Cluster 42: Non-specific - Transcription" "Cluster 70: Brain - Nervous system development" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 64: Astrocytes - Nervous system maintenance" Vesicles "CAB025486: , HPA017613: AB_1850595" "unprognostic (3.22e-3)" "unprognostic (1.06e-2)" "unprognostic (1.64e-1)" "unprognostic (6.41e-2)" "unprognostic (1.47e-1)" "unprognostic (9.16e-2)" "unprognostic (2.25e-1)" "unprognostic (7.58e-2)" "unprognostic (1.33e-2)" "unprognostic (1.06e-6)" "unprognostic (2.62e-1)" "unprognostic (3.21e-1)" 15.6 0.3 172.8 0.2 203.3 0.0 2.5 170.4 162.1 0.2 79.7 0.4 0.1 0.1 0.1 0.1 0.0 0.1 0.2 163.2 156.1 0.1 16.2 0.0 0.2 222.6 182.8 0.0 0.0 0.0 0.8 0.0 183.6 0.2 0.2 1.8 0.2 0.5 0.1 0.0 0.2 0.1 205.7 0.0 0.1 0.2 182.0 0.0 0.0 0.3 0.6 0.0 0.1 212.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 25.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.6 0.1 0.1 0.1 0.1 0.2 0.2 0.1 0.1 0.1 0.1 0.2 0.1 0.2 0.2 0.2 0.1 0.1 0.2 172.8 203.3 170.4 162.1 163.2 156.1 222.6 182.8 183.6 205.7 182.0 212.2 0.1 0.0 0.0 184.8 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 11.2 0.0 0.0 2.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 5.6 0.0 15.5 0.0 72.9 163.2 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 1.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 HOXC12 "HOC3F, HOX3, HOX3F" ENSG00000123407 "Homeobox C12" P31275 12 53954903-53958956 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 14 "adipose tissue: 1.2;brain: 1.1;skin 1: 2.9" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 1.8;stomach cancer: 2.0" "Region enriched" "Detected in single" 5 "cerebral cortex: 1.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HaCaT: 23.4;OE19: 35.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA055632 Uncertain NA NA "Cluster 61: Skin - Cornification" "Cluster 21: OE19 - Mitochondria" "Cluster 33: Fibroblasts - ECM organization" "HPA055632: AB_2682867" "unprognostic (6.95e-2)" "unprognostic (2.34e-2)" "unprognostic (1.10e-1)" "unprognostic (4.37e-2)" "unprognostic (5.98e-2)" "unprognostic (1.45e-1)" "unprognostic (1.17e-3)" "unprognostic (3.84e-2)" "unprognostic (2.55e-1)" 1.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 23.4 0.0 0.0 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.6 0.0 0.0 0.0 0.0 35.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 1.1 0.2 1.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 HOXD3 "HOX1D, HOX4, HOX4A" ENSG00000128652 "Homeobox D3" P31249 2 176136612-176173102 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "epididymis: 42.1" "Cell type enhanced" "Detected in some" "Adipocytes: 6.6;Collecting duct cells: 9.2;Distal tubular cells: 15.6;Early spermatids: 14.4;Endothelial cells: 6.5;Theca cells: 4.7" "Cancer enhanced" "Detected in some" "ovarian cancer: 1.2" "Group enriched" "Detected in many" 8 "medulla oblongata: 8.9;pons: 5.7;spinal cord: 5.7;white matter: 4.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 9.7;HSkMC: 11.2;RPTEC TERT1: 12.0;SCLC-21H: 14.5;SH-SY5Y: 10.1" "Region enriched" "Detected in single" 35 "pons and medulla: 3.5" "Group enriched" "Detected in some" 6 "medulla oblongata: 4.1;pons: 1.1;spinal cord: 3.0" "HPA051831, HPA063671" Supported "Nucleoplasm,Nuclear bodies" No NA "Cluster 68: Epididymis - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "Nuclear bodies" "HPA051831: , HPA063671: AB_2685083" "unprognostic (1.13e-1)" "unprognostic (3.28e-1)" "unprognostic (1.52e-2)" "unprognostic (6.50e-2)" "unprognostic (1.31e-1)" "unprognostic (7.07e-2)" "unprognostic (1.97e-2)" "unprognostic (1.54e-2)" "unprognostic (9.56e-2)" "unprognostic (5.57e-2)" "unprognostic (1.08e-1)" "unprognostic (1.56e-1)" "unprognostic (2.57e-4)" "unprognostic (1.47e-3)" "unprognostic (1.55e-1)" "unprognostic (3.44e-1)" "unprognostic (7.44e-2)" 3.2 2.3 0.2 0.8 0.4 0.0 2.8 0.4 0.3 3.2 0.1 1.0 0.3 6.9 42.1 0.7 6.8 0.6 0.2 0.2 0.4 7.9 0.0 0.2 0.8 8.9 0.8 5.5 0.2 0.1 0.0 0.1 5.7 1.7 0.6 0.0 0.5 7.1 0.7 0.9 0.8 4.1 5.7 0.7 0.3 1.7 0.4 0.2 0.4 0.0 0.2 1.0 2.0 4.9 0.0 0.0 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 1.7 0.2 0.0 0.4 0.0 0.0 0.1 3.6 0.0 0.0 0.1 0.0 0.0 0.0 11.2 0.9 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.1 0.0 0.0 0.0 12.0 0.9 14.5 10.1 0.2 0.1 4.6 0.2 0.0 0.0 1.0 0.2 0.2 1.5 0.8 0.0 0.2 0.0 0.5 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.4 0.3 0.2 0.4 8.9 0.8 5.7 5.7 0.4 4.9 6.6 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.3 15.6 0.0 14.4 0.1 2.1 6.5 1.2 0.0 0.2 0.0 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.8 3.5 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 2.0 0.0 0.3 4.5 0.0 0.1 0.3 2.9 0.0 0.0 0.0 1.3 1.1 0.8 0.5 0.0 1.3 0.0 0.1 4.7 0.6 0.1 HSD17B6 "HSE, RODH, SDR9C6" ENSG00000025423 "Hydroxysteroid 17-beta dehydrogenase 6" O14756 12 56752161-56787790 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 26 "liver: 1804.3" "Cell type enriched" "Detected in many" 11 "Hepatocytes: 1969.3" "Cancer enriched" "Detected in many" 5 "liver cancer: 170.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Karpas-707: 13.4;U-266/84: 18.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA059141 Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 32: T-cells - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 16: U-266 - Nucleosome" "Cluster 2: Hepatocytes - Metabolism" "Nucleoplasm, Vesicles" "HPA059141: AB_2683922" "unprognostic (7.70e-2)" "unprognostic (8.76e-2)" "unprognostic (5.08e-2)" "unprognostic (1.92e-2)" "unprognostic (2.01e-1)" "unprognostic (3.79e-2)" "prognostic favorable (6.32e-4)" "unprognostic (1.06e-2)" "unprognostic (3.21e-1)" "unprognostic (1.44e-1)" "unprognostic (1.35e-1)" "unprognostic (6.74e-2)" "unprognostic (2.50e-10)" "unprognostic (1.26e-1)" "unprognostic (1.79e-1)" "unprognostic (1.08e-1)" "unprognostic (1.05e-1)" 8.5 2.5 13.1 6.9 16.2 0.5 0.7 13.4 18.9 28.0 9.4 24.7 3.2 20.9 1.6 9.9 6.5 9.1 0.8 12.3 12.6 2.5 1804.3 63.2 0.8 12.0 14.6 6.0 0.6 0.5 0.6 5.4 11.5 51.2 7.6 0.8 0.4 69.2 0.4 1.2 4.8 13.1 12.4 47.5 5.7 23.3 13.7 0.9 31.4 0.5 0.9 36.7 14.6 12.8 0.3 0.8 1.9 0.4 1.9 1.4 2.3 4.1 3.5 1.9 1.9 0.4 0.4 12.0 1.7 0.5 0.5 0.3 6.1 1.1 1.1 7.7 2.2 3.7 1.2 0.6 1.2 1.9 6.0 1.0 0.4 1.2 0.6 0.6 0.0 10.3 1.1 13.4 0.9 2.4 5.6 1.3 7.5 0.7 0.7 7.4 0.8 2.9 0.2 1.4 11.0 2.3 2.0 3.6 0.9 0.7 0.6 1.5 0.3 0.9 0.8 4.0 1.0 11.7 18.0 7.8 1.3 6.9 0.6 0.0 0.0 0.0 1.0 0.2 1.2 0.7 0.8 0.8 0.2 0.3 1.1 0.7 0.0 0.0 0.5 0.7 1.0 0.3 13.1 16.2 13.4 18.9 12.3 12.6 12.0 14.6 11.5 12.4 13.7 12.8 0.4 173.1 130.6 21.2 6.1 1.3 3.1 0.6 0.6 0.4 0.7 0.6 0.2 27.1 9.3 0.0 0.0 1.4 0.4 0.0 0.0 0.1 4.6 0.7 3.5 1.3 0.0 29.5 1.4 0.0 2.6 5.0 0.0 0.1 0.0 1.6 26.0 1969.3 0.4 0.0 2.1 0.4 0.0 40.2 0.3 4.5 12.5 0.5 0.0 1.0 1.0 1.3 0.0 3.0 5.5 0.1 0.0 1.5 0.8 16.1 0.0 0.3 1.5 0.6 13.1 0.6 3.5 16.4 11.4 1.2 1.6 0.4 2.2 36.0 0.7 1.1 HYAL1 "HYAL-1, LUCA1" ENSG00000114378 "Hyaluronidase 1" Q12794 3 50299890-50312381 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Disease variant, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 201.6;lymphoid tissue: 95.1" "Cell type enhanced" "Detected in many" "Cholangiocytes: 30.0;Hepatic stellate cells: 33.2;Hepatocytes: 137.1;Proximal tubular cells: 58.2" "Cancer enhanced" "Detected in all" "liver cancer: 37.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 3.1" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 5 "Hep G2: 100.9;SK-BR-3: 28.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002112 Uncertain "Secreted to blood" NA NA 590000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA002112: AB_1857412" "unprognostic (1.39e-1)" "unprognostic (8.68e-2)" "prognostic favorable (2.07e-4)" "unprognostic (5.23e-2)" "unprognostic (3.18e-1)" "unprognostic (8.71e-2)" "unprognostic (9.35e-2)" "unprognostic (3.59e-2)" "unprognostic (6.56e-2)" "unprognostic (1.31e-1)" "unprognostic (6.65e-3)" "unprognostic (1.16e-1)" "prognostic favorable (1.56e-11)" "unprognostic (4.51e-2)" "unprognostic (5.89e-2)" "unprognostic (1.95e-1)" "unprognostic (1.90e-2)" 11.4 21.5 5.0 2.8 4.5 0.3 9.2 6.4 6.3 10.8 18.3 6.8 3.4 8.2 0.8 5.5 7.3 13.2 68.2 4.5 4.0 49.4 201.6 30.7 1.8 5.4 4.8 3.0 9.4 19.9 3.3 2.4 5.6 4.6 2.9 3.1 7.3 2.9 15.0 21.1 6.0 5.9 3.5 95.1 19.4 1.7 5.8 0.8 8.3 19.0 1.2 4.8 12.3 4.7 2.9 1.8 0.4 0.9 0.6 0.7 0.5 0.1 0.3 0.1 0.4 11.4 3.1 0.0 0.8 0.6 0.6 6.6 0.2 0.4 0.0 0.1 0.0 0.3 8.6 100.9 4.4 0.7 0.7 3.9 13.8 0.1 0.4 0.8 2.9 0.3 0.3 0.5 0.4 0.6 0.1 0.3 0.6 7.1 0.6 0.0 0.2 0.3 5.9 0.4 0.2 2.1 0.2 28.0 0.3 2.4 2.0 0.3 1.9 0.6 0.6 0.6 0.3 0.2 0.3 0.4 0.4 0.6 0.3 1.3 0.4 1.5 0.3 0.1 0.8 0.4 0.3 0.4 0.2 0.5 0.6 0.4 3.1 0.3 0.3 0.5 0.4 0.1 5.0 4.5 6.4 6.3 4.5 4.0 5.4 4.8 5.6 3.5 5.8 4.7 18.1 19.2 18.5 1.6 0.3 2.9 0.4 3.3 0.0 1.0 0.3 0.1 20.8 30.0 2.0 11.0 4.2 0.1 0.0 2.5 23.5 16.5 8.2 0.2 0.9 25.8 1.8 2.7 3.1 14.4 0.1 3.3 19.4 0.2 0.0 0.6 33.2 137.1 0.1 0.0 3.1 1.4 0.0 4.4 0.9 7.7 2.1 0.9 0.0 7.5 0.0 0.4 0.0 1.5 1.6 12.1 0.3 1.2 0.0 0.2 0.4 58.2 0.9 0.5 6.6 1.2 4.3 0.4 1.1 0.9 3.1 0.7 0.9 7.4 0.9 1.7 IGFBP5 ENSG00000115461 "Insulin like growth factor binding protein 5" P24593 2 216672105-216695549 "Plasma proteins, Predicted secreted proteins" "Growth factor binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 1492.5;ovary: 1323.4" "Cell type enhanced" "Detected in many" "Fibroblasts: 1104.1;Ionocytes: 980.6;Leydig cells: 1828.2;Peritubular cells: 981.7;Sertoli cells: 1275.3;Skeletal myocytes: 2750.9;Smooth muscle cells: 1376.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 831.3;BJ hTERT+: 2192.6;T-47d: 531.7;U-138 MG: 710.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059827, HPA070407" Supported Approved "Nuclear bodies,Golgi apparatus,Vesicles" "Secreted to blood" NA NA 110000000 380000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Golgi apparatus, Vesicles" "Nuclear bodies" "HPA059827: AB_2732640, HPA070407: " "unprognostic (7.69e-2)" "unprognostic (2.56e-1)" "unprognostic (1.02e-1)" "prognostic unfavorable (1.78e-4)" "unprognostic (4.58e-2)" "unprognostic (3.47e-1)" "unprognostic (2.04e-1)" "unprognostic (1.76e-1)" "unprognostic (1.32e-1)" "unprognostic (9.58e-2)" "unprognostic (1.12e-1)" "unprognostic (2.41e-2)" "unprognostic (4.04e-2)" "unprognostic (9.62e-3)" "unprognostic (1.55e-1)" "unprognostic (3.28e-2)" "unprognostic (1.91e-3)" 375.1 221.8 35.6 178.2 35.1 0.7 354.6 21.9 30.9 1492.5 46.9 232.3 35.0 837.7 121.3 166.4 953.0 129.3 155.0 50.4 41.8 479.1 34.2 78.2 71.3 36.3 37.9 1323.4 30.7 30.7 272.8 290.7 31.5 241.4 66.2 105.4 111.0 121.8 470.9 129.0 139.3 621.2 28.1 38.7 323.5 28.8 43.8 95.0 326.2 292.9 45.9 259.2 382.9 62.4 0.0 0.0 210.6 0.9 237.1 7.5 0.8 831.3 2192.6 108.8 10.4 0.0 1.0 0.1 3.3 2.3 0.0 0.1 26.2 0.0 5.6 0.1 8.2 218.1 4.4 0.2 103.1 0.1 1.8 33.1 0.0 14.7 0.1 24.8 0.1 0.2 0.7 0.1 0.5 70.9 0.9 1.2 2.3 0.0 3.4 0.3 0.8 1.2 70.3 249.1 14.5 8.5 14.6 100.4 0.0 12.8 531.7 0.1 80.3 710.2 42.2 109.3 41.0 0.7 0.1 0.1 1.4 0.1 23.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 35.6 35.1 21.9 30.9 50.4 41.8 36.3 37.9 31.5 28.1 43.8 62.4 237.3 3.2 4.4 40.1 20.6 102.5 13.5 211.0 25.0 8.7 73.9 199.9 92.0 5.7 251.6 112.2 6.2 3.9 1.7 0.0 5.9 10.3 8.4 140.2 250.7 120.8 0.0 0.0 6.0 0.0 4.5 1104.1 30.5 128.5 2.5 11.4 49.6 1.4 8.7 3.3 13.7 0.0 980.6 0.6 189.7 39.9 1828.2 18.4 101.4 29.0 0.6 674.4 0.0 5.5 0.4 2.2 0.0 981.7 5.5 17.0 0.0 1.1 120.9 18.7 1275.3 2750.9 1376.0 2.2 3.0 17.7 67.9 5.6 18.4 124.7 0.1 16.8 IGHG3 ENSG00000211897 "Immunoglobulin heavy constant gamma 3 (G3m marker)" 14 105764503-105771405 "Immunoglobulin genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 7 "lymphoid tissue: 1289.1" "Group enriched" "Detected in many" 7 "B-cells: 2548.4;Plasma cells: 4543.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 415 "memory B-cell: 211.0;naive B-cell: 64.4" "Lineage enriched" "Detected in single" 636 "B-cells: 211.0" "Group enriched" "Detected in some" 5 "HDLM-2: 23.8;Karpas-707: 18.7;U-698: 49.1" "Immunoglobulin genes" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (8.49e-3)" "unprognostic (3.93e-3)" "unprognostic (1.57e-1)" "unprognostic (5.50e-2)" "unprognostic (1.71e-2)" "prognostic favorable (4.00e-5)" "unprognostic (1.92e-2)" "unprognostic (6.65e-2)" "unprognostic (2.33e-2)" "unprognostic (1.99e-2)" "unprognostic (8.36e-2)" "unprognostic (2.06e-1)" "prognostic unfavorable (8.46e-11)" "unprognostic (9.05e-2)" "unprognostic (1.18e-1)" "unprognostic (9.80e-2)" "unprognostic (6.79e-2)" 63.6 17.6 0.1 90.8 0.3 65.4 23.8 0.1 1.5 37.9 1.0 30.0 11.6 22.8 0.3 32.2 104.4 8.4 6.7 0.1 0.6 72.8 42.4 194.9 346.3 2.8 0.1 13.4 6.3 0.1 6.8 0.1 0.4 41.4 8.8 0.0 69.9 12.7 1.9 2.3 100.9 1.6 1.2 1289.1 65.4 31.7 0.1 27.1 87.6 0.0 929.0 87.3 29.6 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 23.8 0.0 0.3 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 18.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 6.0 3.9 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.1 0.1 0.0 49.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 211.0 0.0 0.0 0.0 64.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 20.7 0.1 0.3 0.1 1.5 0.1 0.6 2.8 0.1 0.4 1.2 0.1 1.0 1.9 57.7 363.7 0.0 2548.4 0.0 9.7 0.0 0.0 0.0 0.5 0.1 1.9 18.6 11.2 0.0 0.0 0.0 2.0 7.0 0.0 0.0 6.5 0.1 0.2 5.3 13.2 24.5 0.0 0.0 0.0 9.1 2.6 0.0 195.5 0.0 22.9 64.2 0.1 0.0 0.0 7.4 0.0 62.8 0.0 16.4 0.0 7.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 6.6 0.0 4543.8 13.3 0.0 0.5 2.2 0.0 0.0 0.0 0.7 4.7 0.7 0.0 0.0 0.0 467.3 0.0 13.5 0.1 IGHG4 ENSG00000211892 "Immunoglobulin heavy constant gamma 4 (G4m marker)" P01861 14 105620506-105626066 "FDA approved drug targets, Immunoglobulin genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 2478.2" "Group enriched" "Detected in some" 10 "B-cells: 964.5;Plasma cells: 2099.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 457 "memory B-cell: 122.7;naive B-cell: 73.7" "Lineage enriched" "Detected in single" 571 "B-cells: 122.7" "Cell line enriched" "Detected in some" 6 "RPMI-8226: 339.7" HPA001245 Approved "Immunoglobulin genes" NA NA 170000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA001245: AB_1079121" "unprognostic (7.29e-3)" "unprognostic (5.20e-2)" "unprognostic (1.32e-2)" "unprognostic (3.16e-2)" "unprognostic (1.16e-2)" "prognostic favorable (1.16e-4)" "unprognostic (4.58e-1)" "unprognostic (1.92e-2)" "unprognostic (3.49e-1)" "unprognostic (8.63e-2)" "unprognostic (4.74e-2)" "unprognostic (6.71e-2)" "prognostic unfavorable (9.09e-8)" "unprognostic (2.84e-2)" "unprognostic (4.23e-1)" "unprognostic (9.24e-2)" "unprognostic (7.72e-2)" 80.0 2.1 0.4 2478.2 0.6 42.2 5.8 0.5 1.0 33.9 0.3 40.6 85.5 10.8 0.2 401.2 28.5 101.3 19.2 0.3 0.4 44.0 43.7 49.4 136.5 0.6 0.4 3.9 4.2 0.5 1.9 0.2 1.3 31.2 44.3 0.1 16.4 4.1 0.8 4.7 186.2 1.8 1.1 831.6 57.4 2.2 0.4 49.9 108.3 0.0 872.5 588.7 29.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.2 0.0 0.0 0.3 0.0 0.0 0.0 2.7 0.0 0.5 0.0 0.0 0.0 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 43.2 0.0 0.0 0.3 0.2 0.3 0.0 0.0 0.3 0.6 339.7 0.0 0.0 3.5 3.7 0.3 0.2 0.0 0.0 0.1 0.0 1.0 0.0 0.9 0.3 1.5 0.6 0.1 57.5 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 122.7 0.0 0.0 0.1 73.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 19.6 0.4 0.6 0.5 1.0 0.3 0.4 0.6 0.4 1.3 1.1 0.4 0.3 1.3 6.4 118.8 0.0 964.5 0.0 0.1 0.0 0.0 0.0 0.1 0.0 7.0 8.6 3.7 0.0 0.0 0.0 0.3 11.5 0.0 0.0 0.2 0.0 0.4 2.5 27.8 26.7 0.0 0.0 0.0 4.3 0.0 0.0 50.4 0.0 16.4 36.7 0.0 0.0 0.0 10.5 0.0 51.9 0.0 0.0 0.0 2.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 9.3 0.0 2099.3 0.2 0.0 10.6 0.0 0.0 0.0 0.0 1.9 0.0 0.1 0.0 0.0 0.0 152.3 0.0 12.8 0.1 IGHJ5 ENSG00000242472 "Immunoglobulin heavy joining 5" 14 105863814-105863862 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "adipose tissue: 33.5;breast: 73.2;intestine: 72.3;prostate: 32.7" "Cell type enriched" "Detected in single" 397 "Plasma cells: 39.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 263 "memory B-cell: 1081.0" "Lineage enriched" "Detected in many" 263 "B-cells: 1081.0" "Group enriched" "Detected in some" 11 "HL-60: 10.5;REH: 14.0;RH-30: 18.0" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 85: Liver - Metabolism" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 55: Plasma cells - Humoral immune response" 33.5 0.0 0.7 0.0 3.7 0.0 73.2 0.7 2.0 0.0 2.0 72.3 0.0 0.0 0.0 0.2 0.0 0.0 1.6 0.9 4.2 4.5 29.4 17.1 0.0 3.1 1.0 0.0 4.7 0.0 0.0 0.0 1.9 32.7 0.2 0.2 0.0 0.0 0.0 7.9 0.0 0.0 1.6 0.0 0.0 0.4 1.3 0.0 4.8 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.0 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.6 2.1 1.2 0.7 1081.0 0.4 0.6 4.1 0.0 2.6 0.9 2.3 0.7 0.6 0.0 1.1 316.0 0.7 3.7 0.7 2.0 0.9 4.2 3.1 1.0 1.9 1.6 1.3 1.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHJ6 ENSG00000211900 "Immunoglobulin heavy joining 6" 14 105863198-105863258 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "cervix: 142.4;intestine: 38.6;lung: 47.0;testis: 151.4;urinary bladder: 113.5" "Cell type enriched" "Detected in single" 56 "Plasma cells: 39.7" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 14 "memory B-cell: 316.2;naive B-cell: 112.7" "Lineage enriched" "Detected in many" 21 "B-cells: 316.2" "Cell line enhanced" "Detected in some" "U-266/84: 1.3;U-937: 1.2" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 71: Testis - DNA repair" "Cluster 16: U-266 - Nucleosome" "Cluster 55: Plasma cells - Humoral immune response" 0.0 0.0 0.0 0.0 0.0 1.1 0.7 0.1 0.9 142.4 0.0 2.6 38.6 1.0 0.0 0.0 2.1 0.5 0.9 0.3 0.0 3.0 2.4 47.0 0.4 0.4 0.1 0.0 0.0 3.7 0.0 0.0 0.3 3.6 0.0 0.0 0.0 18.2 0.0 0.0 0.0 0.0 0.0 0.6 0.7 151.4 0.3 0.0 0.7 0.0 10.7 113.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 1.2 0.0 3.5 3.5 0.8 0.3 0.0 0.2 316.2 0.5 0.6 0.5 112.7 0.6 0.3 14.8 0.2 1.0 0.0 0.1 89.2 0.0 0.0 0.1 0.9 0.3 0.0 0.4 0.1 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV1-18 ENSG00000211945 "Immunoglobulin heavy variable 1-18" A0A0C4DH31 14 106184901-106185394 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 223.2;lymphoid tissue: 486.7;salivary gland: 234.3" "Cell type enriched" "Detected in some" 259 "Plasma cells: 13773.3" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 21 "memory B-cell: 73.2" "Lineage enriched" "Detected in many" 21 "B-cells: 73.2" "Cell line enhanced" "Detected in some" "Daudi: 1.6;HL-60: 3.0;RPMI-8226: 2.9;TIME: 1.6" "Immunoglobulin genes" NA NA 4700000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (3.47e-4)" "unprognostic (2.53e-2)" "unprognostic (8.73e-3)" "unprognostic (2.56e-2)" "unprognostic (9.67e-3)" "prognostic favorable (8.27e-4)" "unprognostic (5.47e-2)" "unprognostic (3.52e-1)" "unprognostic (2.65e-1)" "unprognostic (3.50e-2)" "unprognostic (3.60e-1)" "unprognostic (4.26e-1)" "prognostic unfavorable (5.84e-7)" "unprognostic (3.22e-1)" "unprognostic (2.62e-1)" "unprognostic (2.87e-1)" "unprognostic (2.44e-2)" 22.0 3.5 0.0 0.0 0.3 0.0 22.9 0.0 0.6 54.6 0.0 223.2 0.0 8.9 4.5 162.5 24.3 7.7 2.3 0.0 0.0 16.2 14.3 58.3 0.0 0.6 0.1 8.5 3.2 1.9 1.3 0.2 0.4 10.8 0.0 0.0 234.3 0.0 0.4 1.3 103.2 2.6 0.0 486.7 84.0 0.5 0.1 0.0 33.9 0.2 0.0 156.1 12.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 1.3 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 3.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.9 0.0 0.0 0.0 0.6 0.5 0.8 0.0 0.0 1.1 1.2 2.9 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.5 0.4 1.0 0.5 0.0 0.3 0.0 1.4 0.0 3.4 0.0 0.1 0.0 0.0 0.1 73.2 0.0 0.0 0.1 0.0 0.1 0.0 1.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.6 0.1 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 50.6 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 2.5 53.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 13773.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.0 0.0 3.2 0.0 0.1 0.0 IGHV1-2 V35 ENSG00000211934 "Immunoglobulin heavy variable 1-2" P23083 14 105986582-105987083 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 462.7;lymphoid tissue: 1157.3" "Cell type enriched" "Detected in some" 38 "Plasma cells: 609.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 52 "memory B-cell: 285.2;naive B-cell: 347.4" "Lineage enriched" "Detected in many" 57 "B-cells: 347.4" "Cell line enriched" "Detected in some" 8 "U-266/70: 14302.7" "Immunoglobulin genes" NA NA 4000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.63e-3)" "unprognostic (1.09e-3)" "unprognostic (1.88e-1)" "unprognostic (9.46e-2)" "unprognostic (5.78e-2)" "prognostic favorable (1.67e-5)" "unprognostic (9.05e-2)" "unprognostic (1.10e-1)" "unprognostic (1.38e-1)" "unprognostic (2.37e-1)" "unprognostic (1.99e-1)" "unprognostic (4.20e-2)" "prognostic unfavorable (2.02e-4)" "unprognostic (2.17e-2)" "unprognostic (8.59e-2)" "unprognostic (3.19e-1)" "unprognostic (1.17e-2)" 16.7 43.1 0.3 364.1 0.2 76.0 84.1 0.0 1.2 41.5 0.5 462.7 223.7 13.1 1.3 34.5 58.5 54.4 26.2 0.0 0.1 13.7 18.9 60.7 404.9 0.4 0.0 36.5 3.0 0.6 1.3 0.6 0.2 23.2 283.8 0.0 222.4 52.5 0.4 4.5 121.9 7.5 0.2 393.2 216.1 35.0 0.1 72.1 33.7 0.0 1157.3 255.5 8.9 0.6 1.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.0 4.3 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.8 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.8 2.6 0.0 0.0 2.3 0.4 2.8 0.0 0.0 3.1 0.6 0.5 0.0 0.0 1.3 1.8 0.1 0.0 0.6 0.0 0.0 0.2 0.3 0.0 1.5 0.0 1.3 14302.7 1755.5 0.5 0.0 0.4 0.0 0.3 0.6 0.1 0.3 0.0 0.2 285.2 1.6 0.7 0.2 347.4 1.5 0.6 6.1 0.2 0.3 0.5 1.1 34.0 0.3 0.2 0.0 1.2 0.0 0.1 0.4 0.0 0.2 0.2 0.1 0.6 0.0 0.0 1.3 0.0 15.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.1 4.6 0.0 0.0 0.2 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 609.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 IGHV1-46 ENSG00000211962 "Immunoglobulin heavy variable 1-46" P01743 14 106511117-106511856 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 67.9;lymphoid tissue: 125.7;salivary gland: 67.4" "Cell type enriched" "Detected in some" 201 "Plasma cells: 8432.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.7;RPMI-8226: 1.2;SH-SY5Y: 1.2;TIME: 2.3;U-266/70: 1.1;U-266/84: 1.2" "Immunoglobulin genes" NA NA 2900000000 "Cluster 24: B-cells - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (6.28e-4)" "unprognostic (2.49e-2)" "prognostic favorable (7.34e-4)" "unprognostic (1.10e-2)" "unprognostic (3.53e-2)" "unprognostic (1.80e-3)" "unprognostic (1.87e-1)" "unprognostic (6.76e-2)" "unprognostic (8.11e-2)" "unprognostic (2.57e-2)" "unprognostic (1.25e-1)" "unprognostic (3.27e-1)" "prognostic unfavorable (1.56e-6)" "unprognostic (6.19e-2)" "unprognostic (2.52e-1)" "unprognostic (2.27e-1)" "unprognostic (5.13e-1)" 5.1 1.3 0.0 0.0 0.0 0.0 7.2 0.0 0.1 6.2 0.0 67.9 0.0 2.5 1.0 4.9 3.5 0.7 5.0 0.0 0.0 3.2 4.2 15.3 0.0 0.1 0.0 3.0 5.3 0.1 0.3 0.3 0.1 1.9 45.1 0.0 67.4 0.0 0.1 0.7 34.2 0.0 0.0 125.7 25.1 0.2 0.0 0.0 10.5 0.2 0.0 5.1 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.1 0.3 1.2 0.0 0.0 0.5 1.2 0.2 0.0 0.0 0.0 0.1 0.0 2.3 0.0 0.3 0.0 0.1 1.1 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 2.7 0.0 0.0 0.0 1.9 41.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8432.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 IGHV1-69D ENSG00000280411 "Immunoglobulin heavy variable 1-69D" A0A0B4J2H0 14 106762092-106762588 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 2878.6;stomach 1: 989.1" "Group enriched" "Detected in some" 6 "Plasma cells: 5.8;T-cells: 1.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 225 "memory B-cell: 184.5;naive B-cell: 433.4" "Lineage enriched" "Detected in many" 316 "B-cells: 433.4" "Cell line enhanced" "Detected in some" "Daudi: 2.8;HL-60: 2.3;MOLT-4: 4.2;RPMI-8226: 2.5;U-266/70: 3.3;U-698: 7.9" "Immunoglobulin genes" NA NA 1200000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 11: Alveolar cells - Smell perception" "unprognostic (3.32e-3)" "unprognostic (1.75e-2)" "unprognostic (3.87e-2)" "unprognostic (3.77e-2)" "unprognostic (2.49e-4)" "prognostic favorable (2.88e-4)" "unprognostic (1.66e-2)" "unprognostic (1.76e-1)" "unprognostic (1.01e-1)" "unprognostic (1.88e-2)" "unprognostic (1.62e-1)" "unprognostic (3.01e-1)" "prognostic unfavorable (2.72e-8)" "unprognostic (5.14e-2)" "unprognostic (9.96e-2)" "unprognostic (2.84e-2)" "unprognostic (2.08e-2)" 26.1 95.3 0.1 462.7 0.1 113.1 146.7 0.0 0.7 37.5 1.0 628.2 491.2 15.0 16.8 98.6 16.0 78.0 20.2 0.0 0.1 17.5 46.6 149.6 2878.6 1.1 0.0 35.9 3.3 0.6 1.1 0.4 0.1 16.5 406.2 0.0 385.0 100.0 0.5 5.2 121.3 43.8 0.2 452.7 989.1 6.8 0.0 135.7 38.3 0.0 2219.2 295.4 11.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 4.2 0.3 1.3 0.0 0.0 0.9 0.8 2.5 0.0 0.0 0.8 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.5 0.6 0.4 3.3 0.1 7.9 0.0 0.7 0.0 0.8 0.3 0.1 0.0 0.0 0.2 184.5 0.3 0.0 0.2 433.4 0.4 0.1 0.4 0.2 0.4 1.3 0.2 33.5 0.1 0.1 0.0 0.7 0.0 0.1 1.1 0.0 0.1 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 IGHV3-11 ENSG00000211941 "Immunoglobulin heavy variable 3-11" P01762 14 106116635-106117204 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 220.1;lymphoid tissue: 613.1;stomach 1: 206.7" "Cell type enriched" "Detected in some" 142 "Plasma cells: 1655.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 445 "memory B-cell: 43.1;naive B-cell: 45.7" "Lineage enriched" "Detected in single" 458 "B-cells: 45.7" "Cell line enhanced" "Detected in some" "Daudi: 1.1;SH-SY5Y: 1.2" "Immunoglobulin genes" NA NA 18000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (2.07e-3)" "unprognostic (4.84e-2)" "unprognostic (5.81e-3)" "unprognostic (1.07e-2)" "unprognostic (1.04e-2)" "prognostic favorable (3.42e-5)" "unprognostic (4.12e-1)" "unprognostic (6.50e-2)" "unprognostic (2.37e-1)" "unprognostic (3.44e-2)" "unprognostic (3.51e-1)" "unprognostic (2.83e-1)" "prognostic unfavorable (1.52e-5)" "unprognostic (1.43e-1)" "unprognostic (2.97e-1)" "unprognostic (1.86e-1)" "unprognostic (1.30e-1)" 9.3 25.9 0.0 175.0 0.0 38.0 66.0 0.0 0.5 34.7 0.2 220.1 193.4 6.8 12.3 38.6 6.6 43.7 8.6 0.0 0.0 6.8 10.5 29.1 123.7 0.8 0.0 7.8 2.0 0.2 0.8 0.0 0.1 4.0 167.9 0.0 119.7 3.7 0.3 0.7 116.8 11.2 0.1 219.2 206.7 1.3 0.4 44.9 17.0 0.0 613.1 109.4 8.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.1 0.7 0.7 0.0 0.0 0.4 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.1 0.0 0.0 0.0 45.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.5 0.0 0.0 0.8 0.0 0.1 0.1 0.4 0.2 0.0 0.0 0.0 0.0 11.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 3.6 0.0 0.0 0.0 0.7 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1655.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 IGHV3-20 ENSG00000211946 "Immunoglobulin heavy variable 3-20" A0A0C4DH32 14 106210936-106211453 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 99.2;lymphoid tissue: 216.6;stomach 1: 122.5;urinary bladder: 81.9" "Cell type enriched" "Detected in some" 24 "Plasma cells: 142.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 242 "memory B-cell: 28.5;naive B-cell: 19.8" "Lineage enriched" "Detected in single" 286 "B-cells: 28.5" "Cell line enhanced" "Detected in single" "Daudi: 1.2" "Immunoglobulin genes" NA NA 2200000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (2.56e-5)" "unprognostic (2.30e-1)" "unprognostic (9.51e-2)" "unprognostic (1.45e-2)" "prognostic favorable (2.93e-4)" "unprognostic (1.35e-2)" "unprognostic (2.37e-1)" "unprognostic (2.45e-1)" "unprognostic (2.62e-1)" "unprognostic (2.42e-1)" "unprognostic (2.93e-1)" "prognostic unfavorable (2.10e-4)" "unprognostic (2.09e-1)" "unprognostic (1.87e-1)" "unprognostic (1.19e-1)" "unprognostic (1.76e-1)" 2.8 2.1 0.0 36.3 0.2 22.6 23.7 0.0 0.1 17.4 0.2 64.8 99.2 1.8 0.0 10.1 2.2 20.7 3.1 0.0 0.0 1.5 4.7 10.5 58.0 0.1 0.0 2.7 0.4 0.1 0.2 0.0 0.0 1.2 62.5 0.0 43.1 1.4 0.0 0.3 37.7 2.0 0.0 59.6 122.5 1.1 0.0 16.6 2.8 0.0 216.6 81.9 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.5 0.0 0.0 0.0 19.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 142.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 IGHV3-23 ENSG00000211949 "Immunoglobulin heavy variable 3-23" P01764 14 106268606-106269140 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1683.1;lymphoid tissue: 2989.8" "Cell type enriched" "Detected in some" 139 "Plasma cells: 15979.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 406 "memory B-cell: 548.5;naive B-cell: 336.7" "Lineage enriched" "Detected in many" 503 "B-cells: 548.5" "Cell line enhanced" "Detected in some" "BEWO: 4.4;HL-60: 3.3;NB-4: 4.1;RH-30: 3.0;RPMI-8226: 9.0;SH-SY5Y: 5.8" "Immunoglobulin genes" NA NA 42000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.17e-3)" "unprognostic (5.43e-2)" "unprognostic (9.68e-3)" "unprognostic (3.31e-3)" "unprognostic (1.34e-2)" "prognostic favorable (3.85e-4)" "unprognostic (3.26e-1)" "unprognostic (4.79e-1)" "unprognostic (7.26e-2)" "unprognostic (6.52e-3)" "unprognostic (1.72e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.79e-7)" "unprognostic (6.22e-2)" "unprognostic (1.84e-1)" "unprognostic (1.36e-1)" "unprognostic (6.42e-2)" 66.5 189.3 0.4 912.2 0.4 185.5 343.1 0.1 2.1 80.1 1.5 1683.1 1640.8 37.0 9.8 342.6 30.1 231.2 46.4 0.1 0.3 27.3 56.4 248.7 859.5 0.8 0.1 42.6 31.0 1.5 2.7 0.9 0.4 35.3 1087.1 0.1 697.8 53.4 0.9 15.0 886.8 40.0 0.8 802.7 1058.8 35.0 0.2 197.5 52.3 0.1 2989.8 993.6 27.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 3.3 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.2 4.1 0.7 0.0 0.0 0.6 3.0 9.0 0.0 0.0 2.7 5.8 0.8 0.1 0.0 0.0 0.0 0.0 1.8 0.0 1.3 1.3 1.1 1.5 0.0 0.3 0.0 0.9 0.0 0.4 0.4 0.1 0.2 0.0 0.1 548.5 0.2 0.3 0.3 336.7 0.1 0.2 1.0 0.2 0.2 0.2 0.8 62.4 0.4 0.4 0.1 2.1 0.1 0.3 0.8 0.1 0.4 0.8 0.2 1.4 0.1 0.0 0.0 0.0 114.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 12.0 0.0 0.0 0.0 1.6 19.4 0.0 1.3 0.0 1.8 2.0 0.2 0.0 0.0 0.1 0.0 4.1 0.0 0.0 0.0 3.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15979.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 3.9 0.0 0.1 0.0 IGHV3-33 ENSG00000211955 "Immunoglobulin heavy variable 3-33" P01772 14 106359793-106360324 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1066.7;lymphoid tissue: 2371.2;stomach 1: 1778.8" "Cell type enriched" "Detected in some" 26 "Plasma cells: 556.5" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in some" "cerebral cortex: 4.0" "Group enriched" "Detected in many" 101 "memory B-cell: 378.9;naive B-cell: 364.1" "Lineage enriched" "Detected in many" 103 "B-cells: 378.9" "Cell line enhanced" "Detected in some" "HDLM-2: 5.4;HL-60: 5.3;RPMI-8226: 7.7;SH-SY5Y: 3.8;U-266/70: 8.1" "Immunoglobulin genes" NA NA 7500000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.04e-3)" "unprognostic (2.38e-2)" "unprognostic (8.95e-3)" "prognostic favorable (6.36e-4)" "unprognostic (6.84e-2)" "prognostic favorable (7.19e-5)" "unprognostic (1.80e-1)" "unprognostic (1.95e-1)" "unprognostic (7.31e-2)" "unprognostic (3.82e-2)" "unprognostic (1.70e-1)" "unprognostic (5.18e-1)" "prognostic unfavorable (4.10e-6)" "unprognostic (6.23e-2)" "unprognostic (1.69e-1)" "unprognostic (3.26e-1)" "unprognostic (5.92e-2)" 27.9 67.4 1.0 513.8 0.8 117.8 289.5 0.2 4.0 53.6 2.4 1066.7 882.1 16.2 14.5 127.5 18.9 141.9 32.9 0.2 0.4 15.7 41.8 210.1 795.2 1.4 0.2 110.0 29.4 1.9 1.7 0.8 0.4 23.2 775.6 0.0 619.6 39.5 0.5 3.6 343.9 37.3 0.5 476.1 1778.8 29.4 0.7 296.8 42.2 0.1 2371.2 379.8 18.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 5.4 0.0 0.5 0.0 0.0 0.0 5.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 1.9 2.1 0.8 0.0 0.0 0.5 0.2 0.3 0.0 0.0 0.8 2.9 7.7 0.0 0.0 1.4 3.8 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.3 0.7 8.1 0.0 0.2 0.0 0.8 0.0 0.2 0.6 0.1 1.1 0.0 1.9 378.9 3.6 0.9 0.3 364.1 1.4 0.6 1.0 0.2 0.1 0.2 0.5 44.6 1.0 0.8 0.2 4.0 0.2 0.4 1.4 0.2 0.4 0.5 0.7 0.7 0.0 0.0 0.6 0.0 20.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 10.0 2.6 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 556.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 IGHV3-43 ENSG00000232216 "Immunoglobulin heavy variable 3-43" A0A0B4J1X8 14 106470264-106470800 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 211.9;stomach 1: 312.2;urinary bladder: 153.0" "Cell type enriched" "Detected in some" 28 "Plasma cells: 557.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 321 "memory B-cell: 29.4;naive B-cell: 39.0" "Lineage enriched" "Detected in single" 366 "B-cells: 39.0" "Cell line enhanced" "Detected in some" "RPMI-8226: 1.8;SH-SY5Y: 2.3" "Immunoglobulin genes" NA NA 4000000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (2.31e-4)" "unprognostic (2.22e-2)" "prognostic favorable (1.46e-4)" "unprognostic (4.87e-3)" "prognostic favorable (8.20e-4)" "unprognostic (2.36e-1)" "unprognostic (1.34e-1)" "unprognostic (4.63e-1)" "unprognostic (7.27e-3)" "unprognostic (4.50e-2)" "unprognostic (8.73e-2)" "prognostic unfavorable (2.40e-5)" "unprognostic (1.60e-1)" "unprognostic (1.74e-1)" "unprognostic (1.29e-1)" "unprognostic (1.75e-2)" 9.3 2.3 0.0 23.7 0.3 11.5 43.7 0.0 0.3 46.0 0.0 101.8 102.5 2.0 0.0 10.2 3.5 10.7 0.4 0.0 0.0 2.7 9.8 10.8 4.3 0.7 0.0 4.2 2.2 1.0 0.3 0.1 0.2 2.7 66.1 0.0 58.1 5.4 0.1 1.0 48.3 4.4 0.0 83.7 312.2 0.2 0.1 0.0 3.8 0.0 211.9 153.0 4.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.2 1.8 0.0 0.0 0.5 2.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 29.4 0.0 0.0 0.0 39.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.3 0.0 0.3 0.0 0.0 0.7 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 19.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 1.1 0.3 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 557.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 IGHV3-64D ENSG00000282639 "Immunoglobulin heavy variable 3-64D" A0A0J9YX35 14 106088122-106088573 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 145.2;lymphoid tissue: 272.7" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 301 "memory B-cell: 43.3;naive B-cell: 18.7" "Lineage enriched" "Detected in single" 420 "B-cells: 43.3" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 2500000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 7: Non-specific - Mitochondria" 8.3 0.5 0.2 140.3 0.1 10.9 84.2 0.0 0.8 12.9 0.3 130.9 20.4 3.3 1.4 35.4 7.8 46.3 4.8 0.5 0.0 1.5 4.2 36.7 48.8 0.1 0.0 5.1 8.1 0.1 0.1 0.1 0.0 4.1 145.2 0.0 28.9 11.5 0.0 3.8 68.8 3.6 0.1 67.4 74.8 0.5 0.0 16.5 2.9 0.0 272.7 40.5 1.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.3 0.0 0.0 0.0 18.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.7 0.2 0.1 0.0 0.8 0.5 0.0 0.1 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV4-28 ENSG00000211952 "Immunoglobulin heavy variable 4-28" A0A0C4DH34 14 106324254-106324760 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 44.8;lymphoid tissue: 87.4;salivary gland: 39.9;stomach 1: 30.7;urinary bladder: 122.6" "Cell type enriched" "Detected in some" 230 "Plasma cells: 346.4" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 5 "spinal cord: 1.3" "Group enriched" "Detected in some" 206 "memory B-cell: 28.7;naive B-cell: 12.5" "Lineage enriched" "Detected in single" 288 "B-cells: 28.7" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 2500000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (3.14e-3)" "unprognostic (1.32e-2)" "unprognostic (8.05e-2)" "unprognostic (6.64e-3)" "prognostic favorable (2.63e-4)" "unprognostic (1.58e-2)" "unprognostic (7.52e-2)" "unprognostic (1.03e-1)" "unprognostic (5.74e-2)" "unprognostic (4.76e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (4.79e-6)" "unprognostic (1.45e-1)" "unprognostic (1.28e-1)" "unprognostic (2.72e-1)" "unprognostic (1.75e-1)" 1.8 11.3 0.0 40.9 0.0 6.0 12.9 0.0 0.2 3.3 0.1 44.8 44.8 1.0 0.0 12.5 1.9 7.7 1.2 0.0 0.0 1.8 2.4 8.9 10.0 0.0 0.0 3.5 0.4 0.0 0.2 0.0 0.0 0.8 44.1 0.0 39.9 1.7 0.0 0.5 30.2 2.0 1.3 42.3 30.7 0.5 0.0 5.8 4.3 0.0 87.4 122.6 1.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.6 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.7 0.0 0.0 0.0 12.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 346.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 IGHV4-31 ENSG00000231475 "Immunoglobulin heavy variable 4-31" A0A087WSY4 14 106349283-106349792 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 467.7;urinary bladder: 190.8" "Cell type enriched" "Detected in some" 183 "Plasma cells: 1651.6" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in single" "spinal cord: 1.6" "Group enriched" "Detected in some" 48 "memory B-cell: 43.6;naive B-cell: 19.4" "Lineage enriched" "Detected in single" 66 "B-cells: 43.6" "Cell line enhanced" "Detected in some" "RPMI-8226: 1.4;SH-SY5Y: 1.0" "Immunoglobulin genes" NA NA 710000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.53e-3)" "unprognostic (9.05e-2)" "unprognostic (1.12e-1)" "prognostic favorable (5.74e-4)" "prognostic favorable (4.64e-5)" "unprognostic (1.16e-2)" "unprognostic (2.22e-1)" "unprognostic (1.04e-1)" "unprognostic (5.05e-2)" "unprognostic (1.72e-2)" "unprognostic (9.75e-2)" "prognostic unfavorable (6.38e-6)" "unprognostic (2.00e-1)" "unprognostic (1.48e-1)" "unprognostic (3.63e-1)" "unprognostic (1.09e-1)" 4.3 1.7 0.0 48.0 0.0 5.4 37.6 0.0 0.3 15.4 0.0 103.8 72.1 6.5 1.5 32.2 5.3 105.2 11.7 0.0 0.7 3.9 6.3 19.1 104.0 0.2 0.2 58.0 4.7 0.2 0.5 0.0 0.1 11.4 24.9 0.0 53.2 8.4 0.1 1.3 90.4 3.1 1.6 138.6 87.8 1.3 0.2 76.0 15.7 0.0 467.7 190.8 4.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.3 0.7 0.0 0.0 0.0 0.0 0.4 1.4 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.6 0.1 0.0 0.0 19.4 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.5 0.0 0.0 0.0 0.3 0.0 0.7 0.2 0.2 0.1 1.6 0.2 0.1 0.0 0.0 0.0 0.0 9.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 4.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1651.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 IGHV4-34 ENSG00000211956 "Immunoglobulin heavy variable 4-34" P06331 14 106373663-106374145 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 283.3;urinary bladder: 278.5" "Cell type enriched" "Detected in some" 197 "Plasma cells: 15696.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "neutrophil: 1.1" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 602 "U-698: 5353.4" "Immunoglobulin genes" NA NA 4300000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (5.34e-3)" "unprognostic (1.32e-1)" "unprognostic (2.25e-2)" "unprognostic (5.34e-3)" "unprognostic (6.12e-2)" "prognostic favorable (2.77e-4)" "unprognostic (8.06e-2)" "unprognostic (3.89e-1)" "unprognostic (1.23e-1)" "unprognostic (4.27e-2)" "unprognostic (2.68e-1)" "unprognostic (1.75e-1)" "prognostic unfavorable (2.55e-6)" "unprognostic (2.61e-1)" "unprognostic (1.01e-1)" "unprognostic (1.75e-1)" "unprognostic (7.51e-2)" 7.9 3.0 0.0 0.0 0.3 0.0 9.8 0.1 1.5 12.0 0.1 83.5 0.0 5.5 0.9 7.3 22.5 0.0 2.3 0.0 0.2 7.2 7.0 33.4 0.0 0.6 0.2 22.0 1.3 0.4 0.9 0.3 0.3 3.8 2.2 0.0 82.1 0.0 0.3 2.8 54.2 0.3 0.1 283.3 48.0 0.3 0.1 0.0 19.3 0.0 0.0 278.5 4.0 1.4 3.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.5 2.6 3.2 0.0 0.0 1.4 0.0 4.1 0.0 0.3 0.0 0.6 3.7 0.0 0.1 8.8 0.4 1.8 0.0 0.8 5353.4 0.0 3.2 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.1 0.0 0.1 0.5 0.0 0.8 0.0 0.3 0.1 1.5 0.0 0.2 0.6 0.2 0.3 0.1 0.1 1.4 0.0 0.0 0.0 0.0 79.4 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 53.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15696.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 5.6 0.0 0.0 0.0 IGHV4-39 ENSG00000211959 "Immunoglobulin heavy variable 4-39" P01824 14 106421711-106422218 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 251.6;lymphoid tissue: 474.9;salivary gland: 247.1;urinary bladder: 541.3" "Cell type enriched" "Detected in some" 432 "Plasma cells: 48104.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.6;naive B-cell: 1.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BEWO: 2.3;Daudi: 1.8;HL-60: 2.4;NB-4: 2.2;RH-30: 2.1;RPMI-8226: 1.4;U-266/70: 2.1;U-698: 2.0" "Immunoglobulin genes" NA NA 5000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.18e-3)" "unprognostic (2.99e-3)" "unprognostic (5.95e-3)" "unprognostic (1.46e-2)" "unprognostic (5.65e-2)" "unprognostic (2.38e-3)" "unprognostic (4.48e-2)" "unprognostic (2.63e-1)" "unprognostic (1.77e-1)" "unprognostic (2.23e-2)" "unprognostic (2.35e-1)" "unprognostic (2.15e-1)" "prognostic unfavorable (2.60e-6)" "unprognostic (2.04e-2)" "unprognostic (2.77e-1)" "unprognostic (7.68e-2)" "unprognostic (8.33e-2)" 17.8 6.5 0.5 378.0 0.5 14.5 33.2 0.1 0.8 24.0 1.5 251.6 4.4 12.5 2.5 19.1 17.7 0.0 11.4 0.1 0.2 13.8 13.8 54.9 0.0 0.8 1.2 17.6 3.7 1.2 1.4 0.0 0.6 7.1 5.0 0.0 247.1 9.5 0.5 12.1 143.6 2.0 0.1 474.9 108.1 1.3 0.4 2.8 37.2 0.0 5.3 541.3 13.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 2.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.3 0.0 0.0 1.1 2.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.6 0.0 0.2 0.2 0.0 2.1 0.0 2.0 0.0 0.3 0.0 0.4 0.1 0.0 0.0 0.0 0.2 1.6 0.1 0.1 0.1 1.7 0.5 0.1 1.1 0.1 0.1 0.2 0.1 0.0 0.5 0.5 0.1 0.8 0.1 0.2 0.8 1.2 0.6 0.1 0.4 0.3 0.0 0.0 0.0 0.0 89.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 111.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 48104.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 6.3 0.0 0.3 0.0 IGHV4-4 ENSG00000276775 "Immunoglobulin heavy variable 4-4" A0A075B6R2 14 106011922-106012420 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 567.7;urinary bladder: 768.4" "Cell type enriched" "Detected in some" 285 "Plasma cells: 2624.9" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 10 "midbrain: 4.8" "Group enriched" "Detected in some" 23 "memory B-cell: 56.6;naive B-cell: 31.2" "Lineage enriched" "Detected in many" 30 "B-cells: 56.6" "Cell line enriched" "Detected in some" 18 "Karpas-707: 34.5" "Immunoglobulin genes" NA NA 3800000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.03e-3)" "unprognostic (1.93e-2)" "unprognostic (1.50e-1)" "prognostic favorable (1.60e-6)" "unprognostic (2.24e-1)" "unprognostic (6.27e-2)" "unprognostic (1.30e-1)" "unprognostic (2.10e-1)" "unprognostic (7.45e-2)" "prognostic unfavorable (1.69e-5)" "unprognostic (3.16e-1)" "unprognostic (2.59e-1)" "unprognostic (1.55e-1)" "unprognostic (2.05e-1)" 9.4 2.5 0.0 131.4 0.0 17.8 63.6 0.0 0.2 37.5 0.1 205.2 159.9 3.8 0.8 59.8 53.4 104.9 0.9 0.0 0.1 5.5 6.6 36.9 173.2 0.3 4.8 10.0 6.0 0.4 0.4 0.0 0.1 4.0 140.2 0.0 78.2 15.0 0.3 3.8 78.6 13.4 0.4 186.4 175.0 1.6 0.1 31.8 16.7 0.0 567.7 768.4 5.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.5 34.5 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.1 0.8 0.2 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 56.6 0.2 0.2 0.0 31.2 0.6 0.0 0.0 0.0 0.0 1.9 0.6 4.1 0.0 0.0 0.0 0.2 0.0 0.1 0.3 4.8 0.1 0.4 0.1 0.1 0.0 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2624.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 IGHV4-59 ENSG00000224373 "Immunoglobulin heavy variable 4-59" P01825 14 106627249-106627825 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 525.9;lymphoid tissue: 911.2;urinary bladder: 702.5" "Cell type enriched" "Detected in some" 301 "Plasma cells: 12374.9" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in some" "spinal cord: 2.0" "Group enriched" "Detected in some" 37 "memory B-cell: 169.0;naive B-cell: 77.2" "Lineage enriched" "Detected in many" 51 "B-cells: 169.0" "Cell line enhanced" "Detected in some" "MOLT-4: 8.1;SCLC-21H: 2.0;SH-SY5Y: 4.2" "Immunoglobulin genes" NA NA 5500000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.62e-5)" "unprognostic (3.95e-2)" "unprognostic (7.25e-3)" "unprognostic (9.13e-2)" "unprognostic (1.13e-2)" "prognostic favorable (9.18e-5)" "unprognostic (2.88e-2)" "unprognostic (3.55e-1)" "unprognostic (2.16e-1)" "unprognostic (3.22e-2)" "unprognostic (2.22e-1)" "unprognostic (3.68e-1)" "prognostic unfavorable (1.41e-7)" "unprognostic (6.04e-2)" "unprognostic (2.24e-1)" "unprognostic (1.94e-1)" "unprognostic (1.76e-1)" 23.9 3.2 0.0 260.5 0.3 95.5 89.3 0.0 1.1 40.4 0.8 525.9 301.0 12.1 2.7 89.6 17.9 168.0 27.9 0.0 0.6 13.8 20.6 89.9 148.0 0.3 0.1 23.5 10.3 1.7 1.5 0.3 0.2 12.6 456.0 0.0 225.7 8.8 0.5 3.6 222.6 19.5 2.0 465.3 260.5 15.0 0.2 86.4 44.1 0.0 911.2 702.5 10.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.1 1.6 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.1 0.0 1.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.8 0.0 0.0 0.0 8.1 1.0 0.3 0.3 0.0 0.8 1.0 0.7 0.0 0.0 2.0 4.2 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.4 0.0 0.4 0.4 0.1 1.7 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 169.0 0.0 0.2 1.4 77.2 0.1 0.0 0.0 0.0 0.1 3.3 0.1 11.9 0.0 0.3 0.0 1.1 0.0 0.6 0.3 0.1 0.2 2.0 0.2 0.3 0.0 0.0 0.6 0.0 41.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 11.2 0.0 0.0 0.0 0.7 1.2 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 12374.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 3.6 0.0 0.5 0.0 IGHV4-61 ENSG00000211970 "Immunoglobulin heavy variable 4-61" A0A0C4DH41 14 106639119-106639657 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 206.7;lymphoid tissue: 385.2;stomach 1: 143.1" "Cell type enriched" "Detected in some" 98 "Plasma cells: 2432.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 43 "memory B-cell: 39.0;naive B-cell: 25.5" "Lineage enriched" "Detected in single" 52 "B-cells: 39.0" "Cell line enriched" "Detected in single" 11 "MOLT-4: 8.7" "Immunoglobulin genes" NA NA 4400000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (2.11e-3)" "unprognostic (6.59e-2)" "unprognostic (4.92e-2)" "unprognostic (1.12e-2)" "prognostic favorable (3.71e-6)" "unprognostic (6.96e-2)" "unprognostic (5.98e-2)" "unprognostic (1.26e-1)" "unprognostic (1.72e-2)" "unprognostic (9.95e-2)" "unprognostic (9.02e-2)" "prognostic unfavorable (4.13e-6)" "unprognostic (3.55e-2)" "unprognostic (3.10e-1)" "unprognostic (4.24e-1)" "unprognostic (2.32e-2)" 6.4 44.4 0.0 97.5 0.1 30.8 56.0 0.0 0.2 10.1 0.1 206.7 185.7 5.8 0.0 15.5 5.0 22.4 3.1 0.0 0.1 5.5 10.5 28.2 54.4 0.3 0.1 10.4 1.3 0.2 0.7 0.0 0.3 4.1 121.8 0.0 104.3 7.0 0.2 0.7 86.5 8.0 0.3 181.3 143.1 0.9 0.0 30.1 23.0 0.0 385.2 43.9 5.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.4 0.0 0.0 8.7 0.8 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.4 0.5 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.2 0.5 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 39.0 0.0 0.1 0.0 25.5 0.0 0.0 0.0 0.0 0.0 0.7 0.0 4.6 0.0 0.1 0.0 0.2 0.0 0.1 0.3 0.1 0.3 0.3 0.0 0.1 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.8 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2432.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 IGHV5-10-1 IGHV5-A ENSG00000282651 "Immunoglobulin heavy variable 5-10-1" A0A0J9YXX1 14 106107972-106108464 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 316.6;lymphoid tissue: 568.1" "Cell type enriched" "Detected in single" 36 "B-cells: 3.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 15 "memory B-cell: 74.8;naive B-cell: 66.7" "Lineage enriched" "Detected in many" 16 "B-cells: 74.8" "Group enriched" "Detected in some" 6 "Daudi: 9.4;U-698: 4.8" HPA006014 Approved "Immunoglobulin genes" NA NA 1200000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "HPA006014: " 4.5 28.4 0.0 229.8 0.0 38.7 102.0 0.0 0.9 68.9 0.1 274.0 0.9 10.8 0.0 111.5 20.0 92.5 6.2 0.0 0.0 5.5 7.3 128.3 121.2 0.1 0.0 54.0 5.7 0.4 0.3 0.2 0.2 6.9 316.6 0.0 75.5 19.0 0.1 1.6 51.6 10.9 0.0 203.8 148.3 0.1 0.0 39.3 7.3 0.0 568.1 196.6 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.4 0.0 4.8 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 74.8 0.0 0.0 0.0 66.7 0.0 0.0 4.6 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV1-12 "IGKV112, L19" ENSG00000243290 "Immunoglobulin kappa variable 1-12" A0A0C4DH73 2 89040224-89040745 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 395.8;lymphoid tissue: 788.8" "Cell type enriched" "Detected in some" 92 "Plasma cells: 12442.9" "Cancer enhanced" "Detected in many" "stomach cancer: 17.2" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 820 "memory B-cell: 259.8;naive B-cell: 164.2" "Lineage enriched" "Detected in single" 1005 "B-cells: 259.8" "Cell line enhanced" "Detected in some" "BEWO: 1.5;Daudi: 2.1;RPMI-8226: 1.9;SH-SY5Y: 1.9" HPA048721 Approved "Immunoglobulin genes" NA NA 13000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (6.09e-4)" "prognostic favorable (1.59e-4)" "unprognostic (7.33e-2)" "unprognostic (3.74e-2)" "prognostic favorable (3.85e-5)" "unprognostic (5.89e-2)" "unprognostic (5.74e-1)" "unprognostic (7.13e-2)" "unprognostic (6.15e-2)" "unprognostic (3.90e-1)" "prognostic unfavorable (6.59e-8)" "unprognostic (1.18e-1)" "unprognostic (1.84e-1)" "unprognostic (2.68e-1)" "unprognostic (1.71e-1)" 13.6 144.8 0.0 201.7 0.2 73.1 116.8 0.0 0.4 50.8 0.2 395.8 240.6 7.3 0.0 57.1 16.2 69.6 9.9 0.1 0.1 13.7 17.8 65.3 238.6 0.6 0.0 18.1 7.2 0.2 1.4 0.0 1.1 7.2 278.6 0.0 219.0 5.4 0.4 2.8 231.2 11.2 1.2 360.5 254.9 6.7 0.0 69.5 32.7 0.0 788.8 243.3 9.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 1.9 0.0 0.0 0.5 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.2 0.1 0.1 0.0 0.0 259.8 0.0 0.1 0.1 164.2 0.0 0.1 0.2 0.1 0.1 0.1 0.1 24.3 0.0 0.2 0.0 0.4 0.1 0.1 0.6 0.0 1.1 1.2 0.0 0.3 0.0 0.0 0.0 0.0 134.3 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.2 1.3 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 20.4 0.0 0.0 0.0 1.8 1.6 0.0 0.0 0.0 0.1 0.0 2.1 0.0 0.3 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12442.9 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.3 0.0 0.3 5.0 0.0 0.0 0.0 IGKV1-16 "IGKV116, L1" ENSG00000240864 "Immunoglobulin kappa variable 1-16" P04430 2 89099859-89100361 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 279.7;lymphoid tissue: 597.8;urinary bladder: 260.3" "Cell type enriched" "Detected in some" 559 "Plasma cells: 18463.6" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 523 "memory B-cell: 164.7;naive B-cell: 112.8" "Lineage enriched" "Detected in single" 621 "B-cells: 164.7" "Cell line enhanced" "Detected in single" "RPMI-8226: 1.0" HPA048721 Approved "Immunoglobulin genes" NA NA 10000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (2.63e-4)" "unprognostic (7.81e-2)" "unprognostic (1.43e-3)" "unprognostic (2.61e-2)" "unprognostic (3.22e-2)" "unprognostic (1.12e-3)" "unprognostic (1.69e-2)" "unprognostic (1.87e-1)" "unprognostic (8.35e-2)" "unprognostic (3.24e-2)" "unprognostic (1.30e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.06e-5)" "unprognostic (2.84e-1)" "unprognostic (1.17e-1)" "unprognostic (3.84e-2)" "unprognostic (5.82e-2)" 11.8 4.7 0.1 159.1 0.1 40.0 75.9 0.0 0.8 76.0 0.6 279.7 199.4 6.3 0.5 34.3 6.6 99.0 11.4 0.0 0.1 9.2 14.9 40.5 155.0 0.2 0.0 17.7 2.0 0.1 3.6 0.1 0.1 5.6 235.6 0.0 126.9 30.9 0.8 0.7 143.6 11.8 0.1 315.4 158.9 2.0 0.1 45.7 18.4 0.0 597.8 260.3 5.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.4 0.0 0.0 0.1 0.2 1.0 0.0 0.0 0.8 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 164.7 0.0 0.0 0.1 112.8 0.0 0.1 0.2 0.0 0.0 0.0 0.0 16.9 0.1 0.1 0.0 0.8 0.0 0.1 0.2 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 33.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.6 21.4 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.3 0.0 1.1 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18463.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.2 0.0 IGKV1-27 "A20, IGKV127" ENSG00000244575 "Immunoglobulin kappa variable 1-27" A0A075B6S5 2 89213423-89213928 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 268.0;lymphoid tissue: 347.1;salivary gland: 177.6" "Cell type enriched" "Detected in some" 126 "Plasma cells: 4951.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 683 "memory B-cell: 152.7;naive B-cell: 185.3" "Lineage enriched" "Detected in single" 748 "B-cells: 185.3" "Cell line enhanced" "Detected in single" "BEWO: 1.8" "Not detected" "Not detected" HPA048721 Approved "Immunoglobulin genes" NA NA 8300000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (2.56e-5)" "unprognostic (6.50e-3)" "unprognostic (2.65e-2)" "unprognostic (1.68e-3)" "unprognostic (1.72e-2)" "prognostic favorable (8.14e-4)" "unprognostic (9.60e-2)" "unprognostic (1.31e-1)" "unprognostic (2.41e-1)" "unprognostic (6.99e-3)" "unprognostic (9.31e-2)" "unprognostic (1.71e-1)" "prognostic unfavorable (8.84e-5)" "unprognostic (3.23e-2)" "unprognostic (1.34e-1)" "unprognostic (2.34e-1)" "unprognostic (2.67e-2)" 17.2 9.2 0.0 133.5 0.0 28.5 70.0 0.0 0.4 16.8 0.1 268.0 183.3 6.2 7.7 30.4 6.9 37.5 10.7 0.1 0.1 11.8 9.7 55.2 124.7 0.7 0.3 8.8 4.9 0.2 1.0 0.0 0.1 6.4 212.3 0.0 177.6 8.8 0.6 0.9 200.2 5.1 0.2 276.9 91.9 1.0 0.0 46.9 19.4 0.0 347.1 87.7 6.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.3 0.4 0.6 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.7 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.1 0.1 152.7 0.1 0.1 0.1 185.3 0.0 0.0 0.1 0.1 0.1 0.0 0.0 15.8 0.0 0.0 0.0 0.4 0.1 0.1 0.7 0.3 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 39.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.3 12.2 0.0 0.0 0.0 1.1 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4951.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 IGKV1-6 ENSG00000239855 "Immunoglobulin kappa variable 1-6" A0A0C4DH72 2 88966262-88966767 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 155.5;lymphoid tissue: 606.3" "Cell type enriched" "Detected in some" 33 "Plasma cells: 877.6" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 801 "memory B-cell: 123.6;naive B-cell: 85.7" "Lineage enriched" "Detected in single" 946 "B-cells: 123.6" "Not detected" "Not detected" HPA048721 Approved "Immunoglobulin genes" NA NA 12000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (3.44e-5)" "unprognostic (5.25e-3)" "unprognostic (3.78e-2)" "unprognostic (8.68e-3)" "unprognostic (3.23e-2)" "prognostic favorable (1.81e-4)" "unprognostic (3.86e-3)" "unprognostic (3.86e-2)" "unprognostic (3.00e-2)" "unprognostic (5.80e-2)" "unprognostic (1.90e-1)" "unprognostic (3.12e-1)" "prognostic unfavorable (4.37e-6)" "unprognostic (5.23e-3)" "unprognostic (3.02e-1)" "unprognostic (2.54e-1)" "unprognostic (2.54e-1)" 8.2 1.7 0.1 84.1 0.1 37.0 50.3 0.0 0.4 16.5 0.1 155.5 110.5 4.0 4.1 23.5 5.0 18.1 5.3 0.0 0.0 7.7 6.3 20.0 82.3 0.1 0.1 4.0 1.8 0.0 1.1 0.0 0.0 4.3 145.9 0.0 95.0 2.2 0.2 0.6 59.1 5.1 0.2 209.5 130.3 0.7 0.0 22.7 16.4 0.0 606.3 144.8 8.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 123.6 0.0 0.0 0.1 85.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 14.1 0.1 0.1 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 26.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 877.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 IGKV1-9 "IGKV19, L8" ENSG00000241755 "Immunoglobulin kappa variable 1-9" A0A0C4DH69 2 89009982-89010515 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 428.1;lymphoid tissue: 671.3;stomach 1: 283.7" "Cell type enriched" "Detected in some" 116 "Plasma cells: 7178.3" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in single" "cerebral cortex: 1.3" "Group enriched" "Detected in some" 705 "memory B-cell: 300.5;naive B-cell: 296.8" "Lineage enriched" "Detected in single" 709 "B-cells: 300.5" "Cell line enhanced" "Detected in some" "HL-60: 1.2;NB-4: 1.0;RPMI-8226: 2.9;TIME: 1.2" HPA048721 Approved "Immunoglobulin genes" NA NA 4500000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (2.10e-7)" "unprognostic (1.30e-2)" "unprognostic (1.95e-2)" "unprognostic (2.55e-3)" "unprognostic (4.70e-2)" "prognostic favorable (4.91e-4)" "unprognostic (3.30e-2)" "unprognostic (1.57e-1)" "unprognostic (1.09e-2)" "unprognostic (6.80e-2)" "unprognostic (1.95e-2)" "unprognostic (1.65e-1)" "prognostic unfavorable (6.04e-8)" "unprognostic (4.03e-2)" "unprognostic (1.08e-1)" "unprognostic (1.47e-1)" "unprognostic (3.40e-1)" 12.6 12.6 0.2 184.3 0.4 53.6 202.8 0.0 1.3 15.8 0.4 428.1 267.0 8.3 0.8 52.9 78.3 30.0 13.9 0.1 0.1 15.4 17.9 40.1 201.8 0.3 0.1 20.7 2.5 0.5 1.3 0.1 0.2 12.8 348.6 0.0 221.3 13.3 0.5 1.6 182.8 13.3 0.4 313.1 283.7 35.1 0.1 85.1 34.2 0.0 671.3 187.5 8.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.3 1.0 0.3 0.0 0.0 0.0 0.9 2.9 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.1 0.0 0.5 0.0 0.2 0.0 0.2 0.0 0.2 0.4 0.1 0.2 0.0 0.1 300.5 0.1 0.0 0.3 296.8 0.0 0.1 0.3 0.2 0.2 0.1 0.3 34.5 0.2 0.4 0.0 1.3 0.1 0.1 0.3 0.1 0.2 0.4 0.1 0.3 0.0 0.0 0.0 0.0 61.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 10.7 0.0 0.0 0.0 1.8 0.7 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7178.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.0 IGKV2-30 ENSG00000243238 "Immunoglobulin kappa variable 2-30" P06310 2 89244781-89245596 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 631.0;lymphoid tissue: 670.2;stomach 1: 323.1" "Cell type enriched" "Detected in some" 365 "Plasma cells: 25365.6" "Cancer enhanced" "Detected in many" "stomach cancer: 26.0" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 316 "memory B-cell: 561.0;naive B-cell: 325.4" "Lineage enriched" "Detected in many" 400 "B-cells: 561.0" "Cell line enriched" "Detected in some" 388 "U-698: 8426.0" "Immunoglobulin genes" NA NA 6800000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (6.84e-5)" "unprognostic (1.26e-2)" "unprognostic (2.88e-2)" "unprognostic (1.41e-1)" "prognostic favorable (6.78e-5)" "unprognostic (6.92e-2)" "unprognostic (1.20e-2)" "unprognostic (1.45e-2)" "unprognostic (9.82e-3)" "unprognostic (1.84e-1)" "unprognostic (3.07e-1)" "prognostic unfavorable (4.53e-6)" "unprognostic (1.74e-1)" "unprognostic (1.23e-1)" "unprognostic (1.53e-1)" "unprognostic (3.50e-1)" 15.0 9.4 0.1 160.7 0.2 75.9 237.0 0.1 1.3 19.6 0.7 631.0 394.3 5.6 0.8 37.8 11.5 35.0 17.9 0.1 0.1 15.1 29.6 67.3 176.7 1.4 0.1 15.8 7.8 0.1 2.3 0.2 0.2 7.8 324.5 0.0 220.5 23.3 0.6 2.0 260.2 19.1 0.6 670.2 323.1 21.2 0.1 40.9 18.8 0.0 600.3 207.5 21.5 1.1 5.3 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 13.1 4.6 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.0 1.3 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.8 0.3 0.0 0.0 0.1 2.7 1.9 0.0 0.4 0.0 0.9 3.8 0.0 2.6 0.0 0.0 5.6 0.0 0.0 21.7 0.1 2.6 0.3 1.7 8426.0 0.0 2.7 0.0 0.5 0.4 0.2 0.2 0.0 0.2 561.0 0.1 0.2 0.4 325.4 0.0 0.2 1.4 0.2 0.3 0.7 0.3 53.3 0.1 0.2 0.1 1.3 0.1 0.1 1.4 0.1 0.2 0.6 0.1 1.1 0.0 0.0 0.0 0.0 69.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 1.3 30.5 0.0 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25365.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 3.2 0.0 0.3 0.0 IGKV2D-29 ENSG00000243264 "Immunoglobulin kappa variable 2D-29" A0A075B6S2 2 89947512-89948279 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 252.2;lymphoid tissue: 464.7" "Cell type enriched" "Detected in some" 8 "Plasma cells: 184.8" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebral cortex: 1.3" "Group enriched" "Detected in some" 253 "memory B-cell: 360.5;naive B-cell: 489.4" "Lineage enriched" "Detected in many" 292 "B-cells: 489.4" "Cell line enhanced" "Detected in some" "Daudi: 8.5;HDLM-2: 1.2;TIME: 2.1;U-698: 2.2" "Immunoglobulin genes" NA NA 1500000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (3.31e-4)" "unprognostic (2.43e-2)" "unprognostic (1.34e-3)" "unprognostic (1.76e-2)" "prognostic favorable (8.34e-4)" "unprognostic (4.43e-3)" "unprognostic (1.54e-1)" "unprognostic (2.34e-1)" "unprognostic (2.47e-2)" "unprognostic (5.09e-2)" "unprognostic (8.87e-2)" "prognostic unfavorable (2.97e-4)" "unprognostic (9.46e-2)" "unprognostic (2.20e-1)" "unprognostic (2.61e-1)" "unprognostic (7.80e-2)" 11.3 1.0 0.0 73.7 0.1 29.4 49.4 0.1 1.3 12.6 0.8 252.2 97.0 3.9 0.0 9.5 6.5 14.2 3.8 0.1 0.2 3.6 8.4 41.4 139.4 0.3 0.0 9.8 2.8 0.2 0.3 0.0 0.2 3.6 110.9 0.0 106.8 10.3 0.4 3.0 67.9 2.9 0.4 170.2 126.0 1.0 0.1 38.0 7.8 0.0 464.7 35.1 2.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.6 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.9 0.3 0.0 0.0 0.2 0.7 0.3 0.0 0.0 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.1 0.2 0.1 0.0 2.2 0.0 0.1 0.0 0.3 0.4 0.2 0.1 0.0 0.2 360.5 0.2 0.1 0.6 489.4 0.0 0.1 1.6 0.2 0.4 0.2 0.2 42.2 0.0 0.1 0.1 1.3 0.1 0.2 0.3 0.0 0.2 0.4 0.1 0.2 0.0 0.0 0.0 0.0 22.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 184.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 IGKV3-15 ENSG00000244437 "Immunoglobulin kappa variable 3-15" P01624 2 89085177-89085787 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 785.8;lymphoid tissue: 1996.3;urinary bladder: 784.8" "Cell type enriched" "Detected in some" 85 "Plasma cells: 22923.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 561 "memory B-cell: 2243.8;naive B-cell: 1651.4" "Lineage enriched" "Detected in all" 646 "B-cells: 2243.8" "Cell line enhanced" "Detected in some" "Daudi: 1.7;K-562: 1.3;NB-4: 1.9;RH-30: 1.2;RPMI-8226: 2.2;SCLC-21H: 1.4;SH-SY5Y: 2.5" HPA047702 Approved "Immunoglobulin genes" NA NA 7200000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "prognostic favorable (1.57e-4)" "unprognostic (1.29e-2)" "unprognostic (7.02e-3)" "unprognostic (3.89e-3)" "unprognostic (9.06e-3)" "unprognostic (2.06e-3)" "unprognostic (5.36e-2)" "unprognostic (3.55e-1)" "unprognostic (1.45e-1)" "unprognostic (5.82e-3)" "unprognostic (1.45e-1)" "unprognostic (1.21e-1)" "prognostic unfavorable (3.15e-7)" "unprognostic (2.00e-1)" "unprognostic (2.54e-1)" "unprognostic (2.07e-1)" "unprognostic (1.17e-1)" 47.9 114.5 0.0 603.8 0.1 131.0 174.3 0.0 1.5 141.8 0.3 785.8 431.4 19.4 34.7 120.0 30.0 144.4 14.8 0.1 0.3 35.2 36.7 184.8 500.9 0.7 0.3 55.4 9.3 2.5 3.0 0.5 0.3 18.3 649.4 0.0 399.3 114.2 1.0 2.7 335.8 29.5 1.5 1020.7 629.8 64.8 0.2 250.2 77.7 0.0 1996.3 784.8 28.6 1.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.4 1.9 0.6 0.0 0.0 0.0 1.2 2.2 0.0 0.0 1.4 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.3 0.4 0.7 0.5 0.0 0.0 0.0 1.0 0.0 1.8 3.4 0.8 1.0 0.4 0.8 2243.8 1.0 1.1 1.8 1651.4 1.0 1.1 1.9 1.0 1.3 1.7 1.5 193.1 0.0 0.1 0.0 1.5 0.1 0.3 0.7 0.3 0.3 1.5 0.2 1.0 0.0 0.0 0.0 0.0 269.5 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 2.6 73.4 0.0 0.0 0.0 1.4 1.1 0.0 0.0 0.0 0.1 0.0 1.6 0.0 0.1 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 22923.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 252.5 0.0 0.0 0.2 0.0 0.0 28.2 0.0 0.0 0.0 IGKV3-7 ENSG00000243063 "Immunoglobulin kappa variable 3-7 (non-functional)" A0A075B6H7 2 88978468-88979081 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 18.6;lymphoid tissue: 22.2;salivary gland: 15.9;stomach 1: 10.2" "Group enriched" "Detected in some" 37 "B-cells: 1.5;Plasma cells: 5.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 61 "memory B-cell: 27.8;naive B-cell: 24.3" "Lineage enriched" "Detected in single" 65 "B-cells: 27.8" "Not detected" "Not detected" HPA047702 Approved "Immunoglobulin genes" NA NA 850000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "prognostic favorable (1.17e-4)" "unprognostic (3.07e-3)" "unprognostic (3.96e-2)" "unprognostic (1.28e-2)" "unprognostic (1.20e-3)" "unprognostic (1.19e-1)" "unprognostic (5.91e-2)" "unprognostic (2.73e-1)" "unprognostic (4.24e-2)" "unprognostic (2.15e-1)" "unprognostic (1.44e-1)" "prognostic unfavorable (1.27e-5)" "unprognostic (1.16e-1)" "unprognostic (1.40e-1)" "unprognostic (4.46e-2)" "unprognostic (2.64e-2)" 0.3 0.4 0.0 15.0 0.0 4.2 3.9 0.0 0.0 2.1 0.0 18.6 15.1 0.3 0.1 1.5 0.1 1.3 0.0 0.0 0.0 0.2 0.5 1.8 2.5 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.4 13.6 0.0 15.9 0.1 0.0 0.0 11.2 0.7 0.0 4.9 10.2 0.0 0.0 1.4 0.1 0.0 22.2 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.8 0.0 0.0 0.0 24.3 0.0 0.0 0.4 0.0 0.0 0.0 0.1 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV3D-20 ENSG00000211625 "Immunoglobulin kappa variable 3D-20" A0A0C4DH25 2 90038848-90039479 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 131.8;lymphoid tissue: 275.4" "Cell type enriched" "Detected in some" 38 "Plasma cells: 289.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 1042 "memory B-cell: 197.3;naive B-cell: 99.0" "Lineage enriched" "Detected in single" 1388 "B-cells: 197.3" "Cell line enriched" "Detected in some" 4 "U-266/70: 19.5" HPA047702 Approved "Immunoglobulin genes" NA NA 11000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "prognostic favorable (6.82e-4)" "unprognostic (4.70e-3)" "unprognostic (3.16e-2)" "unprognostic (8.10e-3)" "unprognostic (2.05e-1)" "unprognostic (2.60e-3)" "unprognostic (3.37e-1)" "unprognostic (1.68e-1)" "unprognostic (5.15e-2)" "unprognostic (2.53e-2)" "unprognostic (2.29e-1)" "unprognostic (2.11e-1)" "prognostic unfavorable (3.56e-6)" "unprognostic (7.10e-2)" "unprognostic (2.05e-1)" "unprognostic (1.84e-1)" "unprognostic (1.73e-1)" 4.0 6.3 0.0 81.2 0.0 16.0 32.4 0.0 0.6 12.2 0.1 131.8 55.9 2.7 0.0 15.3 4.2 16.2 6.4 0.0 0.1 3.0 6.4 20.6 73.5 0.2 0.1 7.1 3.3 0.0 0.3 0.1 0.1 3.7 88.1 0.0 64.0 3.3 0.1 2.6 77.7 6.0 0.3 88.4 82.5 1.2 0.0 16.2 5.2 0.0 275.4 38.1 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 19.5 4.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 197.3 0.0 0.1 0.1 99.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 34.1 0.0 0.0 0.0 0.6 0.0 0.1 0.2 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 289.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 IGLC7 ENSG00000211685 "Immunoglobulin lambda constant 7" 22 22922594-22923034 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "intestine: 88.1;lymphoid tissue: 107.7;salivary gland: 70.1;stomach 1: 113.1" "Cell type enriched" "Detected in some" 10 "B-cells: 109.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 341 "memory B-cell: 128.8;naive B-cell: 133.0" "Lineage enriched" "Detected in single" 346 "B-cells: 133.0" "Cell line enriched" "Detected in some" 913 "Karpas-707: 122629.0" "Immunoglobulin genes" NA NA "Cluster 37: B-cells - Transcription" "Cluster 64: Macrophages - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.20e-3)" "unprognostic (5.94e-2)" "unprognostic (3.91e-1)" "unprognostic (2.16e-2)" "prognostic favorable (2.03e-4)" "unprognostic (2.11e-1)" "unprognostic (9.60e-3)" "unprognostic (2.47e-2)" "unprognostic (1.88e-1)" "unprognostic (2.74e-1)" "unprognostic (4.11e-1)" "prognostic unfavorable (1.61e-6)" "unprognostic (2.86e-1)" "unprognostic (2.14e-1)" "unprognostic (1.30e-1)" "unprognostic (9.62e-2)" 5.6 4.7 0.0 27.9 0.0 19.9 15.6 0.0 0.4 5.1 0.0 54.1 88.1 4.4 0.5 8.4 4.3 10.7 1.4 0.0 0.5 2.3 3.5 8.3 40.8 0.3 0.0 2.5 1.7 0.1 0.2 0.0 0.2 4.4 23.1 0.0 70.1 0.6 0.1 0.2 23.1 0.9 0.0 107.7 113.1 0.8 0.1 20.0 5.7 0.0 104.2 19.0 2.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 85.8 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.2 112.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 122629.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 134.3 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 2.7 3.0 0.6 111.2 0.0 47.3 0.3 0.1 0.0 0.0 0.1 0.0 128.8 0.0 0.0 0.1 133.0 0.0 0.2 0.1 0.0 0.1 0.3 0.1 25.5 0.0 0.0 0.0 0.4 0.0 0.5 0.3 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.0 109.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 2.5 0.0 0.4 3.7 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.0 0.0 IGLJ1 ENSG00000211674 "Immunoglobulin lambda joining 1" A0A0A0MT76 22 22893692-22893818 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in many" 6 "intestine: 95.1;lymphoid tissue: 50.0;salivary gland: 32.5;stomach 1: 40.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 25 "memory B-cell: 19.6;naive B-cell: 11.0" "Lineage enriched" "Detected in single" 31 "B-cells: 19.6" "Group enriched" "Detected in some" 6 "Daudi: 274.6;U-266/70: 310.0;U-698: 88.7" "Immunoglobulin genes" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "unprognostic (4.18e-4)" "unprognostic (4.80e-3)" "unprognostic (6.97e-2)" "unprognostic (4.68e-1)" 2.3 0.6 0.1 43.3 0.1 9.8 1.8 0.2 0.6 0.0 0.4 17.1 95.1 0.8 0.0 2.0 0.4 5.1 0.2 0.0 0.1 0.2 0.1 2.7 50.0 0.5 0.1 0.5 0.0 0.0 0.0 0.2 0.3 0.6 13.5 0.0 32.5 0.0 0.0 0.0 43.4 2.6 0.2 31.5 40.8 1.3 0.2 5.2 0.0 0.0 34.5 4.5 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 274.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.3 3.3 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 310.0 37.0 88.7 0.0 0.9 0.0 0.0 0.1 0.1 0.1 0.0 0.0 19.6 0.0 0.0 0.0 11.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.7 0.1 0.1 0.2 0.6 0.0 0.1 0.5 0.1 0.3 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLJ2 ENSG00000211676 "Immunoglobulin lambda joining 2" 22 22899481-22899655 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 260.8;lymphoid tissue: 189.8;stomach 1: 212.7" "Cell type enriched" "Detected in single" 5 "Plasma cells: 1.7" "Group enriched" "Detected in many" 8 "colorectal cancer: 12.9;endometrial cancer: 21.6" "Not detected" "Not detected" "Group enriched" "Detected in many" 12 "memory B-cell: 876.1;naive B-cell: 864.5" "Lineage enriched" "Detected in many" 12 "B-cells: 876.1" "Cell line enhanced" "Detected in some" "Daudi: 10.8;HMC-1: 34.1;RH-30: 89.7;U-698: 19.8" NA NA "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (6.99e-3)" "unprognostic (5.36e-2)" "unprognostic (5.54e-2)" "unprognostic (1.13e-2)" "unprognostic (5.94e-7)" "unprognostic (1.51e-2)" "unprognostic (3.63e-2)" "unprognostic (3.66e-2)" "unprognostic (5.17e-2)" "unprognostic (2.92e-1)" 8.4 54.9 0.2 173.0 0.0 25.4 11.2 0.1 0.8 6.1 0.1 134.5 260.8 2.9 4.2 13.5 1.0 12.5 2.9 0.1 0.2 2.1 6.9 21.5 94.5 0.3 0.0 4.7 5.9 0.1 0.0 0.0 0.9 4.0 31.1 0.0 75.6 4.2 0.0 0.2 206.0 1.9 0.1 128.3 212.7 2.3 0.0 15.5 0.3 0.0 189.8 60.8 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.8 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 34.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.9 0.0 0.0 0.0 0.7 89.7 1.3 0.0 0.0 0.8 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 1.0 0.0 0.6 19.8 0.0 0.5 0.0 1.4 1.9 0.6 0.4 0.2 0.7 876.1 0.3 0.3 0.9 864.5 0.2 0.4 9.3 0.7 0.8 71.8 0.5 136.5 0.2 0.0 0.1 0.8 0.1 0.2 0.3 0.0 0.9 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLV1-36 ENSG00000211655 "Immunoglobulin lambda variable 1-36" A0A0B4J1U3 22 22431958-22432465 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 268.7;stomach 1: 122.4;urinary bladder: 86.4" "Cell type enriched" "Detected in some" 13 "Plasma cells: 59.2" "Cancer enhanced" "Detected in many" "lung cancer: 33.3" "Not detected" "Not detected" "Group enriched" "Detected in some" 625 "memory B-cell: 60.9;naive B-cell: 85.8" "Lineage enriched" "Detected in single" 731 "B-cells: 85.8" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 980000000 "Cluster 37: B-cells - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.55e-4)" "unprognostic (5.15e-2)" "unprognostic (2.04e-2)" "prognostic favorable (2.60e-4)" "unprognostic (1.11e-3)" "unprognostic (1.15e-2)" "unprognostic (1.50e-1)" "unprognostic (6.51e-2)" "unprognostic (2.12e-1)" "unprognostic (4.53e-2)" "unprognostic (2.37e-1)" "prognostic unfavorable (1.64e-5)" "unprognostic (2.99e-2)" "unprognostic (5.76e-2)" "unprognostic (1.54e-1)" "unprognostic (1.07e-1)" 1.8 0.3 0.0 19.6 0.0 14.4 23.7 0.0 0.1 6.0 0.0 28.2 21.6 0.7 0.6 10.5 9.1 7.3 6.0 0.0 0.0 3.3 3.3 8.7 16.6 0.0 0.0 1.7 1.1 0.0 0.1 0.0 0.0 1.6 44.7 0.0 37.3 3.0 0.0 0.6 12.3 0.8 0.0 108.1 122.4 0.3 0.0 30.5 2.8 0.0 268.7 86.4 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 60.9 0.0 0.0 0.0 85.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 59.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 IGLV1-51 ENSG00000211644 "Immunoglobulin lambda variable 1-51" P01701 22 22322472-22322969 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 1318.8;lymphoid tissue: 3027.3;urinary bladder: 1584.8" "Cell type enriched" "Detected in some" 312 "Plasma cells: 34336.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "memory B-cell: 275.9;naive B-cell: 178.3" "Lineage enriched" "Detected in many" 10 "B-cells: 275.9" "Cell line enhanced" "Detected in many" "HEK 293: 17.9" "Immunoglobulin genes" NA NA 1700000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.85e-4)" "unprognostic (1.71e-2)" "unprognostic (3.12e-3)" "unprognostic (1.76e-3)" "unprognostic (1.61e-1)" "prognostic favorable (1.95e-5)" "unprognostic (3.55e-3)" "unprognostic (3.78e-2)" "unprognostic (1.84e-1)" "unprognostic (1.61e-2)" "unprognostic (1.41e-1)" "unprognostic (4.86e-1)" "prognostic unfavorable (1.40e-5)" "unprognostic (1.21e-1)" "unprognostic (5.70e-2)" "unprognostic (1.89e-1)" "unprognostic (1.07e-1)" 43.5 318.8 1.1 484.8 1.9 274.1 627.0 4.6 7.1 73.2 2.0 1318.8 1139.1 38.0 16.9 287.4 52.8 238.0 70.2 1.4 1.6 32.7 53.3 179.1 343.1 4.0 1.4 185.0 39.0 5.8 4.1 1.5 4.2 34.4 930.0 3.1 695.2 49.5 1.9 13.1 702.1 49.8 1.9 934.5 956.7 11.7 1.5 274.0 63.0 1.7 3027.3 1584.8 17.7 2.7 1.3 0.6 1.6 3.8 3.5 1.7 5.9 1.4 3.2 3.1 2.0 2.3 1.0 8.8 1.6 0.8 1.1 3.1 1.9 3.8 2.2 1.4 17.9 3.9 4.5 2.4 0.7 3.4 1.7 5.2 1.0 2.7 0.3 0.4 3.1 0.9 3.9 0.9 3.0 1.6 2.6 3.8 3.0 2.8 4.1 2.3 2.7 8.8 3.6 1.4 8.3 4.9 2.0 1.4 1.8 0.9 2.7 0.3 4.3 4.4 9.2 1.0 1.2 2.0 2.0 2.0 0.4 2.8 0.8 0.1 0.5 0.0 0.2 0.2 26.3 275.9 0.2 0.3 0.1 178.3 0.7 0.5 0.4 0.1 0.3 0.2 0.2 26.4 1.1 1.9 4.6 7.1 1.4 1.6 4.0 1.4 4.2 1.9 1.5 2.7 0.0 0.0 0.5 0.0 109.8 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 4.8 35.7 0.1 0.0 0.0 0.7 1.1 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 34336.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.1 19.3 0.0 0.0 9.4 0.0 0.0 0.0 IGLV2-11 ENSG00000211668 "Immunoglobulin lambda variable 2-11" P01706 22 22792491-22793007 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1542.6;lymphoid tissue: 2926.9" "Cell type enriched" "Detected in some" 85 "Plasma cells: 7693.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 37 "memory B-cell: 1402.5;naive B-cell: 850.1" "Lineage enriched" "Detected in many" 46 "B-cells: 1402.5" "Cell line enhanced" "Detected in some" "Karpas-707: 75.0;U-266/70: 20.9;U-266/84: 15.3" "Immunoglobulin genes" NA NA 980000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (9.76e-3)" "unprognostic (6.86e-2)" "unprognostic (3.46e-3)" "unprognostic (7.67e-3)" "unprognostic (2.82e-3)" "prognostic favorable (4.74e-5)" "unprognostic (1.18e-2)" "unprognostic (1.12e-1)" "unprognostic (9.19e-2)" "unprognostic (1.77e-2)" "unprognostic (2.27e-1)" "unprognostic (2.72e-1)" "prognostic unfavorable (1.38e-7)" "unprognostic (3.93e-2)" "unprognostic (1.51e-1)" "unprognostic (2.58e-1)" "unprognostic (2.27e-1)" 33.6 7.3 0.6 344.7 0.3 157.3 447.8 0.1 2.7 27.7 0.8 1455.8 1542.6 18.4 0.5 212.0 30.0 191.3 44.6 0.2 0.7 22.4 41.1 179.8 680.1 1.5 0.2 30.5 22.4 0.6 2.1 0.5 1.1 17.0 868.3 0.0 425.0 36.0 1.7 2.9 713.8 21.3 0.6 637.7 876.1 75.4 0.5 286.4 62.2 0.0 2926.9 661.1 14.8 2.2 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 3.4 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 75.0 0.0 0.0 0.9 4.6 1.1 0.0 0.0 0.8 2.8 8.3 0.0 0.0 2.9 4.8 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 1.1 0.3 1.6 20.9 15.3 0.0 0.3 1.1 0.0 1.2 1.0 0.7 11.5 0.2 1.4 1402.5 1.5 5.9 0.9 850.1 1.0 4.6 30.2 11.1 0.8 0.9 0.8 149.8 0.6 0.3 0.1 2.7 0.2 0.7 1.5 0.2 1.1 0.6 0.5 2.2 0.0 0.0 0.0 0.0 89.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 15.8 0.0 0.0 0.0 1.4 11.7 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7693.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 IGLV2-23 ENSG00000211660 "Immunoglobulin lambda variable 2-23" P01705 22 22697789-22698407 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 691.1;lymphoid tissue: 1598.0;stomach 1: 672.8" "Cell type enriched" "Detected in some" 132 "Plasma cells: 12487.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 369 "memory B-cell: 2072.7;naive B-cell: 2596.0" "Lineage enriched" "Detected in all" 410 "B-cells: 2596.0" "Cell line enriched" "Detected in some" 10 "Karpas-707: 85411.7" "Immunoglobulin genes" NA NA 540000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (3.43e-5)" "unprognostic (7.99e-2)" "unprognostic (3.89e-2)" "unprognostic (2.35e-3)" "unprognostic (2.73e-2)" "unprognostic (1.30e-2)" "unprognostic (9.33e-2)" "unprognostic (2.13e-1)" "unprognostic (1.19e-1)" "unprognostic (5.45e-2)" "unprognostic (1.63e-1)" "unprognostic (1.48e-1)" "prognostic unfavorable (1.50e-7)" "unprognostic (8.20e-2)" "unprognostic (7.79e-2)" "unprognostic (1.20e-1)" "unprognostic (7.42e-2)" 16.0 38.9 0.7 306.7 0.3 103.6 184.7 0.1 1.5 45.2 0.6 634.1 691.1 16.2 1.3 78.7 25.5 66.8 19.9 0.2 0.1 18.6 26.2 160.8 623.2 1.0 0.1 16.3 8.2 0.6 1.7 0.6 0.4 10.8 457.1 0.0 356.7 38.1 0.5 2.1 517.3 16.1 0.3 530.5 672.8 5.9 0.2 277.6 39.1 0.4 1598.0 274.5 11.9 0.3 0.8 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.2 0.0 0.0 65.3 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 1.3 82.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 85411.7 0.0 0.0 2.2 4.2 0.5 0.0 0.0 0.7 1.9 8843.9 0.0 0.0 2.1 4.5 0.0 4.7 0.0 0.0 1.9 0.0 1.0 0.0 1.1 3.4 0.7 213.9 81.1 0.5 92.6 0.2 35.5 1.8 3.1 1.0 1.6 0.9 1.3 2072.7 1.6 0.8 2.6 2596.0 0.6 0.9 6.3 1.6 1.7 0.9 1.3 231.7 0.7 0.3 0.1 1.5 0.2 0.1 1.0 0.1 0.4 0.3 0.2 0.3 0.0 0.0 0.0 0.0 94.4 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 13.7 0.0 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12487.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 39.5 0.0 0.2 0.0 IGLV2-8 ENSG00000278196 "Immunoglobulin lambda variable 2-8" P01709 22 22822658-22823289 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1141.8;lymphoid tissue: 1012.4" "Cell type enriched" "Detected in some" 80 "Plasma cells: 5288.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 125 "memory B-cell: 1439.0;naive B-cell: 2097.3" "Lineage enriched" "Detected in all" 149 "B-cells: 2097.3" "Group enriched" "Detected in many" 617 "U-266/70: 64161.5;U-266/84: 56786.5" "Immunoglobulin genes" NA NA 1500000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (2.92e-4)" "unprognostic (1.29e-1)" "unprognostic (7.17e-3)" "unprognostic (1.05e-2)" "unprognostic (1.65e-1)" "prognostic favorable (5.07e-5)" "unprognostic (2.74e-2)" "unprognostic (1.51e-1)" "unprognostic (1.34e-1)" "unprognostic (5.05e-2)" "unprognostic (1.61e-1)" "unprognostic (6.55e-2)" "prognostic unfavorable (3.00e-5)" "unprognostic (2.04e-2)" "unprognostic (2.67e-1)" "unprognostic (9.90e-2)" "unprognostic (1.62e-1)" 18.7 7.0 1.1 325.0 0.6 96.0 155.2 0.3 2.4 26.0 1.7 1141.8 977.0 9.4 3.5 91.4 7.9 132.4 30.5 0.3 0.3 15.4 24.3 59.2 228.2 0.8 0.3 57.2 30.3 1.4 1.4 0.2 0.7 9.0 250.6 0.0 255.5 60.3 0.6 1.9 451.5 20.1 0.8 437.7 433.9 3.4 0.3 90.6 23.7 0.0 1012.4 259.0 10.3 1.0 62.7 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 1.7 7.6 0.0 0.0 23.1 0.0 0.0 0.0 22.3 0.0 0.5 0.0 0.0 0.0 0.7 16.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.3 0.0 0.0 11.3 1.9 14.8 0.0 0.0 97.9 0.9 10.1 0.0 0.0 1.4 2.8 0.2 0.0 9.3 0.0 0.0 29.5 0.9 0.0 9.8 0.6 38.9 64161.5 56786.5 20.4 0.0 10.1 0.0 1.2 2.4 0.6 2.1 0.7 0.9 1439.0 1.3 1.5 1.9 2097.3 0.4 1.0 14.1 1.3 1.4 0.6 0.7 174.0 1.1 0.6 0.3 2.4 0.3 0.3 0.8 0.3 0.7 0.8 0.3 1.0 0.0 3.2 0.0 0.0 65.3 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 2.5 0.0 0.7 0.9 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5288.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.0 0.0 0.2 0.0 IGLV3-1 ENSG00000211673 "Immunoglobulin lambda variable 3-1" P01715 22 22880706-22881396 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1234.9;lymphoid tissue: 3325.7;stomach 1: 1460.4" "Cell type enriched" "Detected in some" 321 "Plasma cells: 56277.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 725 "memory B-cell: 779.5;naive B-cell: 1038.5" "Lineage enriched" "Detected in many" 828 "B-cells: 1038.5" "Cell line enhanced" "Detected in some" "Daudi: 14.4;RPMI-8226: 4.5;SCLC-21H: 9.1;SH-SY5Y: 9.9" HPA003285 Approved "Immunoglobulin genes" NA NA 4300000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA003285: AB_1079122" "prognostic favorable (9.70e-5)" "unprognostic (9.06e-2)" "unprognostic (5.39e-3)" "unprognostic (2.37e-2)" "unprognostic (8.13e-2)" "prognostic favorable (1.13e-4)" "unprognostic (2.30e-2)" "unprognostic (1.21e-1)" "unprognostic (1.92e-2)" "unprognostic (1.63e-2)" "unprognostic (2.86e-1)" "unprognostic (2.82e-1)" "prognostic unfavorable (9.06e-9)" "unprognostic (2.70e-2)" "unprognostic (4.35e-1)" "unprognostic (1.30e-1)" "unprognostic (2.69e-1)" 44.5 70.9 0.3 485.2 0.2 332.4 317.1 0.2 2.0 192.0 0.9 1234.9 643.4 39.2 0.0 217.7 19.2 310.4 28.1 0.1 0.4 26.3 70.1 176.2 1117.0 1.0 0.3 34.1 7.6 2.7 2.0 0.7 1.5 21.9 684.4 0.2 627.3 19.6 1.2 4.1 481.7 37.2 0.4 654.2 1460.4 56.0 0.3 335.5 35.9 0.0 3325.7 679.7 30.5 0.9 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 14.4 0.1 0.0 0.0 1.1 0.0 0.0 0.0 1.9 0.0 0.6 0.0 0.0 0.0 2.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 1.2 2.4 0.8 0.0 0.0 0.5 3.0 4.5 0.0 0.0 9.1 9.9 0.5 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.6 0.6 1.7 1.8 1.2 2.8 0.0 0.3 0.0 0.7 1.1 0.5 0.3 0.4 0.4 779.5 0.6 0.2 1.2 1038.5 0.2 0.3 0.6 0.4 0.8 0.5 0.5 52.3 0.3 0.2 0.2 2.0 0.1 0.4 1.0 0.3 1.5 0.4 0.3 0.9 0.0 3.2 0.0 0.0 111.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 122.5 0.0 0.0 0.0 0.0 0.0 10.7 174.8 0.0 0.0 0.0 1.1 1.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 56277.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 11.7 0.0 0.2 0.0 IGLV3-10 ENSG00000211669 "Immunoglobulin lambda variable 3-10" A0A075B6K4 22 22811747-22812281 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 317.0;lymphoid tissue: 707.7;stomach 1: 288.7" "Cell type enriched" "Detected in some" 52 "Plasma cells: 1090.2" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in some" 4 "cerebral cortex: 3.3;medulla oblongata: 1.8" "Group enriched" "Detected in some" 786 "memory B-cell: 548.7;naive B-cell: 315.0" "Lineage enriched" "Detected in single" 998 "B-cells: 548.7" "Cell line enhanced" "Detected in some" "Daudi: 4.9;HL-60: 1.0;RH-30: 1.6" HPA003285 Approved "Immunoglobulin genes" NA NA 2000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA003285: AB_1079122" "unprognostic (6.00e-2)" "unprognostic (2.28e-2)" "unprognostic (1.65e-2)" "unprognostic (1.73e-2)" "unprognostic (6.99e-2)" "prognostic favorable (1.27e-4)" "unprognostic (7.40e-3)" "unprognostic (2.44e-2)" "unprognostic (9.91e-2)" "unprognostic (9.55e-2)" "unprognostic (2.79e-1)" "unprognostic (3.55e-1)" "prognostic unfavorable (6.95e-8)" "unprognostic (9.23e-2)" "unprognostic (1.48e-1)" "unprognostic (1.77e-1)" "unprognostic (6.04e-2)" 33.3 112.9 0.5 144.0 0.4 65.5 111.1 0.1 3.3 41.3 0.6 308.0 176.3 7.6 4.5 56.3 7.9 43.5 20.5 0.1 0.2 12.2 20.8 48.0 230.5 1.8 0.2 14.6 10.8 0.9 0.8 0.4 0.6 11.0 317.0 0.0 139.7 10.8 0.2 8.1 94.9 5.8 0.1 217.1 288.7 97.4 0.2 25.9 8.6 0.0 707.7 140.2 7.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.9 0.3 0.0 0.0 0.0 1.6 0.4 0.0 0.0 0.2 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.4 0.3 0.0 0.0 0.0 0.0 0.5 0.3 0.3 0.2 0.0 0.2 548.7 0.1 0.2 0.2 315.0 0.0 0.2 0.3 0.1 0.1 0.3 0.1 43.2 0.5 0.4 0.1 3.3 0.1 0.2 1.8 0.2 0.6 0.1 0.2 0.2 0.0 0.0 0.6 0.0 20.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 7.1 0.0 1.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1090.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.2 0.0 IGLV3-19 ENSG00000211663 "Immunoglobulin lambda variable 3-19" P01714 22 22720623-22721145 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1026.7;lymphoid tissue: 1979.7;stomach 1: 1240.2" "Cell type enriched" "Detected in some" 61 "Plasma cells: 3121.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 355 "memory B-cell: 618.3;naive B-cell: 503.7" "Lineage enriched" "Detected in many" 391 "B-cells: 618.3" "Cell line enhanced" "Detected in some" "RPMI-8226: 6.2;SCLC-21H: 9.4;SH-SY5Y: 10.7;U-251 MG: 4.2" "Immunoglobulin genes" NA NA 1200000000 "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (5.92e-5)" "unprognostic (1.52e-2)" "unprognostic (1.60e-3)" "prognostic favorable (6.11e-5)" "unprognostic (1.14e-1)" "unprognostic (1.24e-3)" "unprognostic (9.58e-3)" "unprognostic (3.57e-1)" "unprognostic (1.55e-1)" "unprognostic (1.00e-1)" "unprognostic (3.13e-1)" "unprognostic (3.03e-1)" "prognostic unfavorable (9.37e-10)" "unprognostic (2.10e-1)" "unprognostic (2.31e-1)" "unprognostic (2.44e-1)" "unprognostic (8.52e-2)" 49.1 20.1 0.1 402.2 0.3 185.1 313.5 0.1 2.4 69.2 0.3 1026.7 713.6 19.0 263.4 154.0 65.8 182.4 36.9 0.1 0.3 26.0 57.5 192.2 464.9 1.5 0.4 44.9 11.5 1.3 2.7 0.4 0.4 17.2 912.2 0.0 304.9 62.4 0.9 4.8 385.2 34.9 0.6 714.2 1240.2 6.0 0.4 435.0 55.4 0.0 1979.7 642.5 13.6 1.1 0.0 0.0 0.0 0.0 0.0 0.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 1.0 0.8 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.1 2.7 0.3 0.0 0.0 0.1 0.9 6.2 0.0 0.0 9.4 10.7 0.6 0.0 0.0 0.0 0.0 0.0 0.7 0.0 1.4 0.0 4.2 0.8 0.5 0.7 0.0 0.5 0.0 0.4 0.4 1.0 0.5 0.3 0.7 618.3 0.2 0.3 0.5 503.7 0.4 0.3 1.5 0.3 0.4 0.6 0.4 36.2 0.1 0.3 0.1 2.4 0.1 0.3 1.5 0.4 0.4 0.6 0.4 1.1 0.0 0.0 0.0 0.0 51.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 1.4 15.8 0.0 1.3 0.0 2.2 1.8 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3121.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 IGLV3-27 ENSG00000211658 "Immunoglobulin lambda variable 3-27" P01718 22 22668288-22668806 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "lymphoid tissue: 401.6" "Cell type enriched" "Detected in some" 135 "Plasma cells: 1406.5" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 719 "memory B-cell: 194.0;naive B-cell: 367.8" "Lineage enriched" "Detected in single" 941 "B-cells: 367.8" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 720000000 "Cluster 24: B-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (3.45e-2)" "unprognostic (1.87e-3)" "unprognostic (5.44e-2)" "unprognostic (4.30e-3)" "prognostic favorable (3.60e-7)" "unprognostic (8.55e-2)" "unprognostic (2.16e-1)" "unprognostic (5.91e-2)" "unprognostic (9.56e-2)" "unprognostic (4.55e-2)" "unprognostic (1.23e-1)" "prognostic unfavorable (4.95e-9)" "unprognostic (1.82e-2)" "unprognostic (2.09e-1)" "unprognostic (1.90e-1)" "unprognostic (2.07e-1)" 8.8 1.8 0.1 16.4 0.0 29.4 29.7 0.0 0.5 23.7 0.1 56.7 19.3 2.2 0.0 10.3 5.1 10.5 3.1 0.0 0.0 3.7 3.7 29.3 64.3 0.4 0.0 2.9 0.3 0.2 0.4 0.0 0.1 2.4 26.9 0.0 40.6 0.8 0.0 0.5 24.4 0.6 0.0 103.9 59.8 24.2 0.0 47.6 2.8 0.0 401.6 27.4 2.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.1 0.1 194.0 0.2 0.0 0.3 367.8 0.0 0.0 0.2 0.0 0.1 0.1 0.1 11.8 0.1 0.0 0.0 0.5 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1406.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 IGLV3-9 ENSG00000211670 "Immunoglobulin lambda variable 3-9" A0A075B6K5 22 22819010-22819756 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 313.9;stomach 1: 117.3" "Cell type enriched" "Detected in some" 9 "Plasma cells: 13.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 51 "memory B-cell: 64.7;naive B-cell: 168.7" "Lineage enriched" "Detected in many" 74 "B-cells: 168.7" "Cell line enriched" "Detected in some" 5 "U-266/70: 41.3" HPA003285 Approved "Immunoglobulin genes" NA NA 1500000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA003285: AB_1079122" "prognostic favorable (2.59e-4)" "unprognostic (6.52e-3)" "unprognostic (1.95e-1)" "unprognostic (5.40e-2)" "prognostic favorable (9.80e-5)" "unprognostic (1.36e-2)" "unprognostic (1.09e-1)" "unprognostic (1.68e-1)" "unprognostic (1.50e-1)" "unprognostic (2.52e-2)" "unprognostic (3.29e-1)" "prognostic unfavorable (6.00e-7)" "unprognostic (3.47e-2)" "unprognostic (4.58e-2)" "unprognostic (4.55e-2)" "unprognostic (3.22e-1)" 1.8 23.5 0.1 84.6 0.0 27.8 14.9 0.0 0.1 7.3 0.1 87.1 58.7 2.0 0.0 20.8 1.8 18.6 7.6 0.0 0.0 3.2 6.2 17.1 139.8 0.7 0.0 3.9 2.4 0.2 0.1 0.0 0.1 1.4 64.0 0.0 46.2 3.1 0.1 1.5 60.3 5.2 0.0 64.6 117.3 1.6 0.1 35.0 3.8 0.0 313.9 72.3 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 2.1 0.1 0.3 0.0 0.0 0.1 0.4 0.2 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.9 0.3 0.0 41.3 5.8 0.7 0.0 3.9 0.0 0.0 0.1 0.0 1.2 0.0 2.2 64.7 1.3 1.4 0.0 168.7 0.4 1.8 0.1 0.5 0.1 0.0 0.1 6.5 0.1 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.4 0.0 13.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 IGLV4-69 ENSG00000211637 "Immunoglobulin lambda variable 4-69" A0A075B6H9 22 22030934-22031472 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 430.3;lymphoid tissue: 461.2;salivary gland: 116.6;stomach 1: 285.6;urinary bladder: 204.0" "Cell type enriched" "Detected in some" 140 "Plasma cells: 4593.6" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in single" 4 "medulla oblongata: 1.1" "Group enriched" "Detected in some" 302 "memory B-cell: 331.7;naive B-cell: 224.0" "Lineage enriched" "Detected in single" 361 "B-cells: 331.7" "Cell line enhanced" "Detected in some" "Daudi: 1.0;NB-4: 1.0;REH: 1.3;RPMI-8226: 5.4;SH-SY5Y: 1.3" "Immunoglobulin genes" NA NA 320000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.02e-4)" "unprognostic (1.32e-2)" "unprognostic (2.19e-3)" "unprognostic (1.34e-3)" "unprognostic (2.67e-2)" "prognostic favorable (4.04e-5)" "unprognostic (2.59e-3)" "unprognostic (2.50e-1)" "unprognostic (1.67e-1)" "unprognostic (5.57e-2)" "unprognostic (1.85e-1)" "unprognostic (1.93e-1)" "prognostic unfavorable (1.89e-5)" "unprognostic (9.74e-2)" "unprognostic (2.27e-1)" "unprognostic (1.23e-1)" "unprognostic (6.08e-2)" 15.6 9.7 0.0 172.4 0.1 43.2 64.1 0.1 0.2 27.9 0.1 325.8 430.3 5.7 0.2 52.2 5.5 44.1 15.1 0.0 0.0 6.2 14.5 72.1 450.4 1.1 0.0 10.6 8.5 0.3 1.1 0.1 0.2 6.3 209.5 0.0 116.6 6.3 0.2 0.7 219.6 3.4 0.0 305.9 285.6 1.4 0.2 82.1 9.8 0.1 461.2 204.0 5.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 1.0 0.1 0.0 0.0 1.3 0.0 5.4 0.0 0.0 0.7 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.3 0.6 0.0 0.6 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.0 0.1 331.7 0.2 0.1 0.2 224.0 0.0 0.1 0.9 0.1 0.1 0.1 0.2 32.3 0.0 0.1 0.1 0.2 0.0 0.0 1.1 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 32.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.5 11.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4593.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.2 0.0 IGLV6-57 ENSG00000211640 "Immunoglobulin lambda variable 6-57" P01721 22 22195799-22196276 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 1814.6;urinary bladder: 675.2" "Cell type enriched" "Detected in some" 72 "Plasma cells: 10791.0" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "memory B-cell: 353.9;naive B-cell: 292.4" "Lineage enriched" "Detected in many" 13 "B-cells: 353.9" "Cell line enhanced" "Detected in some" "Daudi: 148.0;RPMI-8226: 40.6;U-266/70: 21.6;U-698: 47.3" "Immunoglobulin genes" NA NA 1900000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.92e-6)" "unprognostic (5.73e-2)" "unprognostic (2.59e-2)" "unprognostic (2.11e-2)" "unprognostic (1.14e-2)" "prognostic favorable (1.36e-5)" "unprognostic (1.87e-2)" "unprognostic (2.56e-1)" "unprognostic (6.55e-2)" "unprognostic (3.87e-2)" "unprognostic (1.52e-1)" "unprognostic (1.15e-1)" "prognostic unfavorable (2.30e-6)" "unprognostic (2.82e-1)" "unprognostic (1.23e-1)" "unprognostic (1.52e-1)" "unprognostic (1.11e-1)" 15.6 9.1 0.0 220.8 0.1 191.7 215.5 0.0 0.6 82.3 0.4 485.0 351.3 19.1 4.4 171.4 38.2 75.8 39.2 0.1 0.0 10.7 26.8 97.0 237.6 0.6 0.1 20.3 7.7 17.8 1.1 0.4 0.5 17.2 318.8 0.0 249.6 12.7 0.3 3.2 174.3 11.5 0.1 276.6 437.6 15.9 0.1 139.7 15.3 0.0 1814.6 675.2 8.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 148.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 2.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.9 0.0 0.0 0.0 1.3 0.2 0.0 0.0 0.2 1.0 40.6 0.0 0.0 2.0 1.3 0.3 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.7 0.2 0.4 21.6 15.2 47.3 0.0 0.0 0.0 0.2 0.2 0.2 0.2 0.0 2.3 353.9 0.1 0.1 0.2 292.4 0.1 0.1 27.9 0.1 0.1 1.2 0.2 27.6 0.0 0.1 0.0 0.6 0.1 0.0 0.6 0.1 0.5 0.1 0.1 0.3 0.0 0.0 0.6 0.0 148.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.8 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.3 1.8 26.7 0.0 0.0 0.0 4.4 67.8 0.0 0.0 0.0 3.6 2.8 0.0 0.0 0.0 0.1 0.0 2.8 0.0 0.2 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10791.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.2 0.1 0.0 0.0 6.2 0.0 0.5 0.0 IKZF2 "Helios, ZNFN1A2" ENSG00000030419 "IKAROS family zinc finger 2" Q9UKS7 2 212999691-213152427 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 40.3" "Cell type enhanced" "Detected in many" "Astrocytes: 77.4;Oligodendrocyte precursor cells: 100.5;Oligodendrocytes: 78.3;Squamous epithelial cells: 47.8;Urothelial cells: 51.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "granulocytes: 4.8;NK-cells: 5.5;T-cells: 5.8" "Cell line enhanced" "Detected in many" "JURKAT: 70.5;MOLT-4: 31.1;RT4: 28.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA059142 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Nuclear bodies" Cytosol "HPA059142: AB_2683923" "unprognostic (2.29e-1)" "unprognostic (1.04e-1)" "unprognostic (7.81e-2)" "unprognostic (1.42e-1)" "unprognostic (2.87e-2)" "unprognostic (2.80e-3)" "unprognostic (2.98e-1)" "unprognostic (3.03e-1)" "unprognostic (5.12e-2)" "unprognostic (1.37e-1)" "unprognostic (1.01e-2)" "unprognostic (1.21e-1)" "unprognostic (3.56e-3)" "unprognostic (4.05e-1)" "unprognostic (2.09e-1)" "unprognostic (5.93e-3)" "unprognostic (7.09e-2)" 2.1 2.0 2.6 3.8 5.5 5.5 2.3 3.2 3.2 3.4 0.7 1.8 0.8 1.9 3.2 19.4 2.8 3.1 1.9 2.9 3.8 1.5 1.4 2.9 7.0 5.2 3.5 2.0 2.0 5.2 1.9 2.0 5.3 3.3 1.7 5.5 8.4 4.3 4.1 9.1 1.2 0.8 3.2 5.5 4.4 2.5 3.9 40.3 7.8 1.6 6.8 9.6 8.3 7.4 2.8 1.0 5.3 0.3 17.1 17.2 3.3 3.4 3.9 0.8 1.7 1.4 4.6 3.7 4.4 2.0 0.4 6.5 0.1 1.8 2.7 0.0 0.9 1.9 3.6 0.5 0.1 8.9 0.6 16.9 1.6 0.1 0.5 4.3 0.0 70.5 1.2 3.1 1.6 5.2 31.1 8.9 1.1 2.2 0.8 18.1 3.5 0.0 1.5 28.6 1.6 1.0 0.0 3.6 0.0 4.4 4.8 0.9 9.2 4.9 3.8 2.3 0.7 6.0 2.0 20.6 2.4 0.0 1.1 3.9 0.0 4.8 1.8 0.0 4.9 0.2 0.6 1.4 0.0 1.0 0.3 1.5 0.0 5.5 0.0 0.5 5.8 0.3 2.6 5.5 3.2 3.2 2.9 3.8 5.2 3.5 5.3 3.2 3.9 7.4 2.1 9.6 12.6 77.4 5.2 5.9 23.2 7.9 11.4 4.8 5.1 2.2 7.6 1.5 19.5 7.3 4.2 4.3 27.4 2.8 0.0 2.3 1.3 16.1 1.8 2.4 3.0 9.0 17.7 3.1 1.2 2.7 8.6 18.1 3.8 2.5 2.5 2.2 2.1 0.0 19.9 2.3 4.1 2.4 2.1 0.7 1.8 2.8 1.8 31.9 1.3 3.0 39.1 100.5 78.3 3.6 1.0 2.2 13.9 15.9 1.1 1.0 31.7 7.3 0.0 10.2 4.5 0.8 0.7 47.8 8.7 4.0 22.1 2.0 1.4 51.8 IL1RAP "C3orf13, IL-1RAcP, IL1R3" ENSG00000196083 "Interleukin 1 receptor accessory protein" Q9NPH3 3 190514051-190659750 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Hydrolase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 225.8" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 109.2;Hepatocytes: 295.8;Oligodendrocyte precursor cells: 298.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "eosinophil: 23.8;neutrophil: 95.0" "Lineage enriched" "Detected in many" 15 "granulocytes: 95.0" "Cell line enriched" "Detected in many" 4 "SK-MEL-30: 247.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035293 Uncertain Approved Vesicles,Cytosol "Secreted to blood" NA NA 350000000 "Cluster 1: Neutrophils - Mixed function" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 2: Hepatocytes - Metabolism" "Vesicles, Cytosol" "HPA035293: AB_10671511" "unprognostic (6.48e-2)" "unprognostic (1.02e-1)" "unprognostic (3.04e-2)" "unprognostic (1.04e-2)" "unprognostic (1.37e-1)" "unprognostic (8.84e-3)" "unprognostic (2.35e-2)" "unprognostic (6.60e-2)" "unprognostic (2.62e-1)" "unprognostic (1.28e-1)" "prognostic unfavorable (1.31e-4)" "unprognostic (1.72e-1)" "prognostic unfavorable (2.16e-7)" "unprognostic (4.02e-3)" "unprognostic (9.06e-2)" "unprognostic (5.72e-2)" "prognostic unfavorable (6.29e-4)" 6.2 2.9 4.0 11.4 1.1 20.3 4.3 0.0 8.7 4.4 0.5 2.2 1.8 4.0 2.6 13.1 5.4 12.1 3.9 4.6 3.1 3.3 225.8 8.2 2.7 2.4 3.7 3.0 3.9 1.5 1.2 37.0 3.3 3.9 2.2 2.4 5.2 3.4 1.3 11.9 2.2 6.4 1.5 5.4 4.5 1.3 5.5 4.6 4.0 2.1 4.8 9.4 5.5 3.3 13.3 3.0 5.5 0.8 9.5 7.7 10.0 5.8 11.9 13.4 13.2 5.8 29.3 2.2 59.2 16.4 31.1 34.1 3.0 57.6 18.7 2.5 3.6 2.9 5.3 14.5 19.6 20.2 9.5 10.3 23.1 19.7 59.2 27.8 6.0 5.9 0.4 0.2 6.4 6.5 1.7 9.4 8.5 6.0 6.0 9.5 8.2 4.8 5.3 14.8 1.0 0.0 26.3 15.0 247.1 5.2 9.6 14.6 7.9 10.3 10.4 32.1 26.6 5.0 0.2 0.5 17.2 18.0 60.9 11.7 3.8 23.8 1.8 4.3 3.3 2.1 2.1 2.3 3.8 2.1 2.0 1.3 95.0 0.3 6.3 0.6 2.1 1.4 4.0 1.1 0.0 8.7 4.6 3.1 2.4 3.7 3.3 1.5 5.5 3.3 3.5 0.0 14.7 6.5 6.8 44.7 16.5 45.8 68.9 6.5 2.5 4.7 5.5 40.0 22.8 3.7 8.4 8.5 3.6 1.8 0.0 7.7 4.4 8.6 3.8 8.0 5.4 4.4 44.3 7.5 109.2 7.3 7.1 12.3 7.6 0.7 7.5 295.8 7.8 0.0 63.3 1.4 4.1 33.7 17.7 0.6 4.4 28.8 8.8 53.4 5.0 1.0 6.2 298.6 1.5 19.7 0.8 2.6 5.3 11.5 0.7 1.1 8.7 0.6 0.0 18.0 5.1 0.1 0.6 30.9 37.2 24.2 5.2 1.4 1.1 14.3 IL1RL2 "IL1R-rp2, IL1RRP2" ENSG00000115598 "Interleukin 1 receptor like 2" Q9HB29 2 102187006-102240002 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" "Hydrolase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 12.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 5.6;Excitatory neurons: 9.7;Glandular and luminal cells: 8.4;Langerhans cells: 7.1;Suprabasal keratinocytes: 5.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 8.1;ASC TERT1: 5.1;HaCaT: 3.8;HSkMC: 4.4;hTCEpi: 2.3" "Low region specificity" "Detected in single" "Region enhanced" "Detected in single" "hippocampal formation: 1.0" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "unprognostic (6.70e-2)" "unprognostic (1.17e-1)" "unprognostic (6.57e-2)" "unprognostic (2.76e-4)" "unprognostic (3.42e-3)" "unprognostic (2.60e-1)" "unprognostic (3.13e-3)" "unprognostic (6.79e-2)" "unprognostic (9.10e-3)" "unprognostic (9.17e-2)" "unprognostic (4.61e-2)" "unprognostic (2.38e-1)" "unprognostic (1.05e-2)" "unprognostic (8.33e-3)" "unprognostic (3.80e-1)" "unprognostic (1.47e-1)" "unprognostic (7.65e-2)" 1.0 1.5 0.5 0.5 0.6 0.3 2.6 0.1 0.9 1.5 0.0 0.9 0.1 0.4 1.4 5.8 2.3 2.3 0.5 0.7 1.0 4.3 2.9 0.5 0.0 0.8 0.5 0.3 0.5 2.6 0.3 0.3 0.8 0.9 1.1 0.0 2.2 2.3 0.4 12.3 0.3 0.3 0.1 0.1 1.6 0.1 0.9 0.3 2.4 0.7 1.0 1.0 2.5 0.3 8.1 0.0 0.0 0.0 1.5 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 3.8 0.0 0.6 0.4 0.4 0.0 0.0 1.1 0.0 1.5 0.0 0.0 4.4 2.3 1.2 0.0 0.3 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.1 0.0 0.4 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.1 0.9 0.7 1.0 0.8 0.5 0.8 0.1 0.9 0.3 1.1 0.0 1.1 0.3 0.0 5.6 2.7 0.7 3.4 0.0 2.1 2.4 0.3 1.5 0.4 1.8 0.0 0.1 0.2 0.5 3.9 0.2 0.3 3.8 2.4 0.9 1.2 0.0 9.7 0.2 0.2 1.4 0.5 8.4 0.0 0.0 0.0 1.3 0.6 0.0 1.1 1.1 0.0 2.8 7.1 0.2 1.5 4.2 0.0 1.9 0.6 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.1 2.0 0.0 0.4 0.1 0.0 0.0 1.8 1.7 0.0 0.0 5.2 5.5 0.1 0.2 0.6 0.7 1.8 IL31RA "CRL, CRL3, GLM-R, Glmr, IL-31RA" ENSG00000164509 "Interleukin 31 receptor A" Q8NI17 5 55851357-55922854 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Immunity Receptor "Amyloidosis, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 1.6;lymphoid tissue: 2.1;testis: 1.8" "Cell type enhanced" "Detected in some" "Early spermatids: 2.2;Late spermatids: 1.2;Spermatocytes: 2.5;Syncytiotrophoblasts: 1.1" "Cancer enhanced" "Detected in some" "head and neck cancer: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 26.3;HBEC3-KT: 10.3;HHSteC: 9.5;hTERT-HME1: 11.5;U-2 OS: 16.8;U-87 MG: 20.8" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 1.2" "HPA051532, HPA068114" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles Nucleoplasm "HPA051532: , HPA068114: AB_2732779" "unprognostic (1.14e-1)" "unprognostic (5.65e-2)" "unprognostic (1.97e-1)" "unprognostic (5.13e-2)" "unprognostic (2.70e-2)" "unprognostic (2.95e-3)" "unprognostic (7.34e-2)" "unprognostic (3.54e-1)" "unprognostic (5.38e-2)" "unprognostic (2.95e-3)" "unprognostic (7.75e-5)" "unprognostic (5.55e-2)" "unprognostic (2.65e-6)" "unprognostic (7.73e-2)" "unprognostic (7.68e-2)" "unprognostic (4.02e-1)" "unprognostic (1.76e-2)" 0.0 0.0 0.1 0.3 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.2 0.0 0.4 0.5 0.0 0.1 0.0 0.0 0.1 1.8 0.0 2.1 0.0 0.6 0.1 0.1 0.0 0.0 0.1 1.4 0.0 0.0 0.1 0.4 0.5 0.2 0.5 0.3 0.1 0.0 0.2 0.0 0.0 0.4 26.3 0.0 0.0 10.3 2.2 0.0 0.1 0.0 0.0 0.0 9.5 0.0 0.0 7.3 2.9 4.8 11.5 0.6 4.1 0.1 0.0 0.4 1.4 0.0 0.0 1.2 0.0 0.0 6.8 0.0 1.2 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 3.5 2.0 0.5 16.8 0.0 0.8 0.0 0.0 0.0 20.8 0.0 2.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.2 0.1 0.3 0.3 0.0 0.0 0.3 0.2 0.2 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 1.2 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.1 0.2 0.0 0.1 0.1 0.0 0.0 0.2 0.1 2.5 0.6 0.0 0.1 1.1 0.0 0.7 0.0 0.0 IL34 "C16orf77, IL-34, MGC34647" ENSG00000157368 "Interleukin 34" Q6ZMJ4 16 70579895-70660682 "Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Cytokine, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 106.3;skin 1: 62.0" "Cell type enhanced" "Detected in many" "Leydig cells: 18.3;Peritubular cells: 40.6;Sertoli cells: 19.7;Suprabasal keratinocytes: 20.5;Theca cells: 18.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 13 "eosinophil: 18.5" "Lineage enriched" "Detected in single" 185 "granulocytes: 18.5" "Cell line enhanced" "Detected in some" "ASC TERT1: 2.1;Hep G2: 2.7;HSkMC: 2.4;NTERA-2: 5.3;U-138 MG: 3.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 57100 "Cluster 52: Eosinophils - Transcription" "Cluster 64: Macrophages - Immune response" "Cluster 5: NTERA-2 - Transcription" "Cluster 48: Smooth muscle cells - ECM organization" "unprognostic (3.76e-3)" "prognostic favorable (7.41e-4)" "unprognostic (5.70e-2)" "unprognostic (1.02e-1)" "unprognostic (2.27e-2)" "prognostic favorable (9.69e-4)" "unprognostic (8.19e-2)" "unprognostic (1.59e-3)" "unprognostic (3.83e-2)" "unprognostic (6.11e-3)" "unprognostic (3.18e-2)" "unprognostic (9.92e-2)" "prognostic unfavorable (3.52e-8)" "unprognostic (6.47e-3)" "unprognostic (4.58e-2)" "unprognostic (5.83e-2)" "unprognostic (4.37e-2)" 4.4 22.9 17.1 3.9 18.1 0.1 8.6 8.5 23.3 9.6 23.1 4.0 5.1 2.9 1.0 25.5 3.2 6.7 4.4 22.5 14.5 5.7 2.5 5.0 9.1 13.0 11.7 1.6 1.9 1.0 12.5 0.5 14.1 6.2 2.2 1.2 16.0 3.8 9.6 62.0 6.4 2.5 10.1 106.3 2.4 3.5 19.0 3.9 5.1 2.5 5.0 4.8 13.4 11.6 0.0 0.6 0.1 0.1 0.2 2.1 0.2 0.1 1.8 0.2 0.2 0.4 0.0 0.0 0.3 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 2.7 0.9 0.0 1.6 2.4 0.1 0.1 0.0 0.2 0.5 0.0 0.0 0.0 0.5 0.0 0.0 0.0 5.3 0.0 0.0 0.1 1.7 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.3 0.0 0.0 0.0 3.6 0.1 0.1 0.1 0.2 0.0 0.0 0.3 0.7 0.1 1.4 0.0 18.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.1 18.1 8.5 23.3 22.5 14.5 13.0 11.7 14.1 10.1 19.0 11.6 2.8 0.0 1.8 2.9 0.1 8.3 1.6 3.4 2.2 1.2 15.7 14.7 0.4 1.5 4.9 0.0 4.2 0.1 0.5 0.0 0.0 7.4 0.2 0.5 0.3 6.1 0.0 0.0 12.7 2.0 0.9 9.0 0.0 0.1 0.0 0.0 3.6 0.1 3.8 5.0 11.4 0.1 2.0 0.0 4.2 0.3 18.3 0.4 12.4 5.6 0.0 15.2 0.0 1.5 1.0 0.8 0.1 40.6 0.1 2.4 0.2 0.3 1.2 0.8 19.7 2.0 8.1 0.1 0.4 7.8 20.5 0.8 0.3 18.8 0.5 1.9 IL36RN "FIL1, FIL1(DELTA), FIL1D, IL-1F5, IL1F5, IL1HY1, IL1L1, IL1RP3, IL36RA, MGC29840" ENSG00000136695 "Interleukin 36 receptor antagonist" Q9UBH0 2 113058638-113065382 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Innate immunity" Cytokine "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 26.5;lymphoid tissue: 43.7;skin 1: 60.3" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 8.9;Extravillous trophoblasts: 2.0;Syncytiotrophoblasts: 3.8" "Cancer enriched" "Detected in some" 7 "head and neck cancer: 25.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "BEWO: 26.6;GAMG: 11.1;U-87 MG: 19.9" "Not detected" "Not detected" "Secreted to blood" NA NA 107000 "Cluster 31: Skin - Epidermis development" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "unprognostic (3.88e-3)" "unprognostic (3.16e-1)" "unprognostic (2.88e-1)" "unprognostic (4.29e-1)" "unprognostic (8.68e-3)" "unprognostic (9.80e-2)" "unprognostic (2.48e-1)" "unprognostic (5.99e-2)" "unprognostic (1.24e-2)" "unprognostic (1.39e-1)" "unprognostic (3.99e-2)" "unprognostic (5.37e-2)" "unprognostic (3.85e-3)" "unprognostic (4.23e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 26.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 3.4 0.0 0.0 0.0 0.0 4.6 0.0 0.1 60.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 43.7 0.0 9.1 0.0 1.4 0.0 0.0 0.0 0.0 0.0 26.6 0.0 0.0 0.0 0.0 0.1 1.1 0.3 0.0 0.0 11.1 1.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.9 0.3 0.2 0.1 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 19.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 8.9 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 3.8 0.0 0.0 0.0 0.7 IL3RA CD123 ENSG00000185291 "Interleukin 3 receptor subunit alpha" P26951 X 1336616-1382689 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 79.0;dendritic cells: 137.5;Endothelial cells: 83.2;Langerhans cells: 47.6;monocytes: 72.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 2665.0" "Lineage enriched" "Detected in all" 4 "granulocytes: 2665.0" "Cell line enhanced" "Detected in many" "HDLM-2: 128.8;NB-4: 24.9;RPMI-8226: 54.1" "HPA003539, CAB018374" Uncertain NA NA "Cluster 38: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 44: HDLM-2 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "CAB018374: AB_2233620, HPA003539: AB_1078438" "prognostic favorable (9.78e-4)" "prognostic favorable (4.27e-4)" "unprognostic (8.13e-2)" "unprognostic (9.32e-2)" "unprognostic (2.09e-1)" "unprognostic (1.29e-3)" "unprognostic (1.32e-1)" "unprognostic (1.67e-1)" "unprognostic (1.38e-1)" "unprognostic (3.73e-2)" "unprognostic (5.77e-3)" "unprognostic (1.43e-1)" "unprognostic (1.50e-3)" "unprognostic (9.41e-2)" "unprognostic (2.85e-3)" "unprognostic (2.49e-1)" "unprognostic (1.46e-1)" 25.2 2.9 7.1 15.8 13.6 25.0 20.6 16.1 11.7 6.4 0.2 8.1 5.5 8.7 1.6 5.4 8.0 11.3 13.0 5.9 8.1 9.2 1.8 25.0 25.1 11.7 10.6 8.8 5.4 3.4 2.8 6.2 11.1 7.0 6.6 22.0 9.5 3.2 12.1 12.7 9.2 12.3 7.5 11.1 6.9 3.5 10.1 4.4 10.3 8.6 13.0 12.4 6.3 20.5 0.2 9.4 3.6 1.3 0.1 0.0 1.1 1.2 0.3 0.0 0.1 0.9 1.5 1.2 7.2 0.2 0.6 9.6 0.0 0.0 0.0 128.8 3.9 0.6 2.1 0.4 0.0 0.8 15.6 0.0 0.0 0.0 0.0 4.1 8.2 0.9 0.3 6.1 0.0 1.4 0.7 24.9 3.1 0.8 0.5 1.4 4.2 54.1 0.0 1.4 0.6 0.4 0.6 0.3 2.8 1.8 1.2 17.8 0.4 0.5 1.5 0.5 0.3 12.5 3.9 1.1 9.8 2.8 0.1 2665.0 5.6 83.9 0.6 31.7 1.0 2.5 0.9 0.5 14.9 8.9 0.7 0.7 4.6 14.2 42.5 628.5 0.5 12.0 7.1 13.6 16.1 11.7 5.9 8.1 11.7 10.6 11.1 7.5 10.1 20.5 79.0 3.2 1.8 11.8 6.8 5.9 0.7 0.9 1.2 2.3 0.5 0.9 2.2 1.5 1.0 0.0 10.4 0.1 137.5 4.7 0.0 0.4 0.2 2.7 1.4 83.2 0.0 3.0 7.3 0.2 0.1 4.3 0.5 1.5 11.4 0.4 24.3 0.7 4.6 0.0 14.3 7.3 0.0 2.8 47.6 0.1 0.3 32.9 8.8 13.1 72.6 0.6 1.0 6.0 18.2 0.1 3.4 0.7 4.0 0.7 0.2 0.0 0.4 3.2 0.0 3.6 3.2 0.1 0.7 0.7 5.5 0.3 1.6 1.3 0.6 2.1 INAVA "C1orf106, FLJ10901" ENSG00000163362 "Innate immunity activator" Q3KP66 1 200891048-200915742 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Immunity, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 44.2;intestine: 55.4;skin 1: 47.0" "Cell type enhanced" "Detected in some" "Ductal cells: 33.3;Endometrial ciliated cells: 26.8;Exocrine glandular cells: 45.5;Glandular and luminal cells: 25.1;Pancreatic endocrine cells: 118.6;Proximal tubular cells: 26.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 60.3;CAPAN-2: 49.6;HaCaT: 66.0;OE19: 57.8;RPMI-8226: 54.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA027499, HPA027511, HPA079622" Uncertain Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 1: Pancreatic cells - Digestion" Nucleoplasm "Nuclear bodies" "HPA027499: AB_10599708, HPA027511: AB_10600334, HPA079622: " "unprognostic (3.43e-2)" "unprognostic (1.46e-2)" "unprognostic (1.98e-1)" "prognostic unfavorable (1.78e-5)" "unprognostic (4.56e-2)" "unprognostic (2.18e-1)" "unprognostic (2.74e-2)" "unprognostic (6.62e-3)" "unprognostic (2.84e-2)" "unprognostic (9.38e-2)" "unprognostic (2.52e-2)" "unprognostic (2.81e-1)" "unprognostic (3.23e-3)" "unprognostic (1.67e-1)" "unprognostic (1.28e-1)" "unprognostic (1.27e-1)" "unprognostic (7.73e-2)" 0.1 0.0 1.4 4.0 1.4 4.5 1.7 0.8 1.3 8.8 1.8 33.8 47.3 1.1 0.5 44.2 4.2 16.3 0.2 1.4 1.4 15.3 0.4 3.5 0.4 1.1 1.4 0.1 13.2 0.1 0.3 1.9 1.0 7.0 30.1 0.4 12.3 2.6 0.2 47.0 55.4 1.1 1.0 0.3 27.3 1.1 1.5 0.9 0.1 0.0 5.7 17.1 20.3 1.0 27.5 40.8 23.3 0.0 0.0 0.0 60.3 0.0 0.0 0.7 0.5 43.4 49.6 0.0 13.3 0.0 1.1 66.0 0.0 17.4 0.5 0.0 5.0 3.8 1.8 17.2 0.1 8.5 0.8 0.0 26.1 0.4 1.1 0.6 0.0 0.0 0.0 0.0 0.2 0.4 0.1 1.4 45.2 57.8 9.2 0.2 9.7 54.0 24.4 34.9 0.1 2.8 2.6 41.5 0.0 27.3 17.1 7.9 0.0 0.1 10.1 0.1 2.9 46.2 20.6 0.0 0.1 8.6 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 1.4 1.4 0.8 1.3 1.4 1.4 1.1 1.4 1.0 1.0 1.5 1.0 0.6 12.8 7.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 2.5 3.3 0.0 0.0 5.0 14.7 0.0 7.6 0.1 0.0 5.9 33.3 0.0 26.8 2.2 0.7 0.0 0.0 0.0 45.5 13.2 0.4 0.0 25.1 1.3 0.7 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 118.6 0.0 0.0 0.0 0.0 0.0 26.0 4.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 3.1 0.5 0.3 0.0 0.0 INKA1 "C3orf54, FAM212A" ENSG00000185614 "Inka box actin regulator 1" 3 49803261-49805030 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "skin 1: 24.1" "Cell type enhanced" "Detected in some" "Adipocytes: 19.9;Breast myoepithelial cells: 9.7;Endothelial cells: 8.4;Hofbauer cells: 54.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 59.6;memory B-cell: 65.9;naive B-cell: 64.4" "Group enriched" "Detected in many" 7 "B-cells: 65.9;granulocytes: 59.6" "Cell line enhanced" "Detected in many" "HEL: 68.5;HMC-1: 45.1;NB-4: 38.5;THP-1: 42.1;U-937: 34.9" "Low region specificity" "Detected in all" HPA041879 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 32: U-937 - Innate immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Vesicles" "HPA041879: AB_10797269" "unprognostic (1.36e-1)" "unprognostic (2.99e-2)" "unprognostic (6.97e-2)" "unprognostic (7.95e-2)" "unprognostic (1.34e-1)" "prognostic favorable (1.96e-4)" "unprognostic (2.70e-2)" "unprognostic (4.35e-2)" "unprognostic (7.28e-2)" "unprognostic (2.94e-1)" "unprognostic (3.35e-3)" "unprognostic (4.61e-2)" "unprognostic (1.90e-3)" "unprognostic (4.95e-2)" "unprognostic (3.90e-2)" "unprognostic (1.45e-1)" "unprognostic (1.40e-2)" 5.1 2.3 4.8 2.0 5.0 3.5 4.1 5.2 7.6 6.2 2.8 3.2 0.8 4.7 1.4 19.7 2.8 1.5 5.2 5.3 5.5 5.8 1.1 5.4 4.1 6.2 5.3 2.2 1.3 0.5 2.1 3.1 5.7 6.4 0.5 0.2 4.9 2.1 11.7 24.1 4.3 1.8 5.8 6.7 2.4 2.9 6.5 1.6 2.1 2.3 3.9 5.5 10.3 7.0 1.3 1.1 1.5 1.1 1.8 4.1 0.0 3.0 1.9 1.4 1.7 0.1 0.0 14.9 0.4 2.2 1.5 8.7 0.5 10.4 0.1 2.6 0.0 68.5 0.7 0.2 2.6 10.4 45.1 5.4 14.5 2.9 2.6 0.9 6.1 1.0 4.7 1.2 1.2 0.6 0.9 38.5 1.1 0.0 5.8 13.9 0.8 3.3 0.1 16.9 0.8 5.3 2.7 0.5 1.5 0.4 0.3 42.1 3.8 7.3 0.9 3.4 1.3 1.7 1.7 1.2 3.2 34.9 1.8 59.6 2.4 11.6 1.3 5.9 0.3 65.9 1.5 1.8 0.7 64.4 2.2 3.6 1.3 0.0 8.5 9.3 1.6 6.4 4.8 5.0 5.2 7.6 5.3 5.5 6.2 5.3 5.7 5.8 6.5 7.0 19.9 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 1.0 9.7 0.0 0.0 0.0 0.0 0.0 0.4 1.0 0.0 0.0 0.7 0.0 0.5 1.6 8.4 0.0 0.0 0.0 1.2 0.7 3.0 0.0 0.1 0.0 0.1 0.0 0.0 54.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 3.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 1.1 0.4 0.5 0.0 0.0 IPPK "C9orf12, FLJ13163, INSP5K2, IP5K, IPK1" ENSG00000127080 "Inositol-pentakisphosphate 2-kinase" Q9H8X2 9 92613183-92670131 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 31.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020603 Uncertain Approved Cytosol NA NA "Cluster 13: T-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 28: BEWO - Transcription regulation" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol "HPA020603: AB_1851853" "unprognostic (3.51e-2)" "unprognostic (4.66e-2)" "unprognostic (6.26e-2)" "unprognostic (1.26e-1)" "unprognostic (3.63e-2)" "unprognostic (2.08e-1)" "unprognostic (4.88e-2)" "unprognostic (3.13e-2)" "unprognostic (4.40e-2)" "unprognostic (1.10e-1)" "unprognostic (2.68e-1)" "unprognostic (1.98e-1)" "unprognostic (6.26e-9)" "unprognostic (1.28e-2)" "unprognostic (4.23e-2)" "unprognostic (2.83e-1)" "prognostic unfavorable (1.28e-4)" 5.4 6.9 5.2 4.5 5.7 8.5 6.4 7.5 6.4 9.1 3.9 4.1 3.2 5.2 4.8 31.6 5.4 4.6 7.8 6.9 4.7 4.4 5.3 4.7 5.7 5.5 5.1 5.4 3.6 8.5 8.1 5.5 5.7 4.2 4.4 5.7 8.8 2.8 7.6 29.8 4.2 5.4 5.0 5.4 4.6 11.6 5.6 5.9 4.6 6.1 8.7 5.7 15.5 5.6 19.3 10.1 9.2 8.0 11.1 8.2 30.4 13.5 8.5 13.6 7.8 6.3 7.4 11.9 6.6 18.9 12.0 27.1 16.4 18.9 11.3 14.9 10.4 9.8 21.9 9.9 7.8 16.7 11.2 8.1 18.4 16.3 12.7 12.4 10.3 9.8 13.5 14.1 13.6 26.3 9.6 7.7 15.8 21.2 14.9 8.5 9.8 4.9 8.0 11.5 19.1 11.2 10.9 44.9 7.8 8.9 10.6 4.2 19.7 10.0 11.3 28.2 14.4 13.0 16.2 6.5 13.0 7.5 9.9 0.0 1.4 3.4 3.6 1.8 4.1 2.4 3.0 3.1 2.1 2.2 2.3 2.6 2.1 0.8 1.9 2.3 4.6 1.9 5.2 5.7 7.5 6.4 6.9 4.7 5.5 5.1 5.7 5.0 5.6 5.6 6.8 3.2 3.4 10.1 4.8 25.4 6.4 7.6 16.5 7.5 6.0 4.7 0.4 1.5 5.1 1.8 6.2 10.8 4.6 5.0 5.9 6.2 11.0 8.3 5.3 6.8 6.7 6.1 23.8 8.0 13.8 4.1 7.1 10.2 0.0 3.6 10.0 3.1 5.1 15.2 23.7 3.5 6.1 7.5 4.6 33.7 3.1 5.3 3.6 7.5 2.8 4.9 8.2 20.6 23.3 9.1 1.4 3.0 6.0 6.4 2.6 3.6 2.6 4.6 6.6 3.9 3.5 20.0 19.4 25.5 29.5 22.8 6.0 4.4 3.7 10.5 IQGAP2 ENSG00000145703 "IQ motif containing GTPase activating protein 2" Q13576 5 76403285-76708132 "Plasma proteins, Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 113.1" "Cell type enhanced" "Detected in many" "Early spermatids: 1011.9;Late spermatids: 351.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 21.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 74.2;Hep G2: 61.7;HMC-1: 211.8;RPMI-8226: 81.6;U-937: 57.0" "Region enhanced" "Detected in many" "hippocampal formation: 30.5" "Low region specificity" "Detected in all" "CAB004241, HPA037403, HPA037404" Uncertain Approved "Vesicles,Plasma membrane" NA NA 3700000 "Cluster 18: Basophils - Vesicular transport" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 29: Early spermatids - Spermatogenesis" "Vesicles, Plasma membrane" "CAB004241: AB_2125909, HPA037403: AB_2675459, HPA037404: AB_2675460" "unprognostic (9.46e-2)" "unprognostic (1.27e-1)" "unprognostic (1.35e-1)" "unprognostic (1.48e-1)" "unprognostic (9.03e-3)" "unprognostic (8.85e-2)" "prognostic favorable (5.65e-4)" "unprognostic (5.96e-2)" "unprognostic (1.14e-1)" "unprognostic (2.34e-1)" "unprognostic (2.14e-1)" "unprognostic (1.41e-1)" "prognostic favorable (9.44e-12)" "unprognostic (3.29e-2)" "unprognostic (9.89e-2)" "unprognostic (1.52e-2)" "unprognostic (1.27e-2)" 7.9 12.2 0.8 11.7 0.6 25.0 27.1 0.5 0.7 19.6 2.4 25.7 56.5 3.3 9.5 2.8 3.4 18.6 2.9 0.4 0.9 35.2 113.1 9.9 14.4 2.2 2.5 8.9 25.7 44.3 1.1 30.7 1.9 15.2 23.0 23.9 34.6 15.4 0.3 2.7 31.4 4.3 1.4 13.2 39.1 51.1 2.4 7.3 28.6 1.3 8.2 6.5 1.5 2.4 0.0 9.6 31.5 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 74.2 0.1 0.7 2.7 0.0 2.7 0.2 12.1 0.0 0.1 8.6 12.0 27.6 6.8 61.7 0.2 15.7 211.8 0.0 0.0 0.0 0.0 0.0 1.2 14.9 24.6 21.4 0.0 0.0 13.5 42.4 14.8 25.4 0.3 4.9 0.1 81.6 0.0 0.1 0.6 3.2 17.3 0.9 0.1 31.4 0.0 9.3 0.4 0.0 0.5 0.0 0.3 19.8 0.0 18.7 0.1 57.0 3.0 21.3 3.1 1.9 4.5 2.5 3.7 0.5 4.7 3.9 2.9 0.2 1.8 3.3 6.0 4.3 3.4 7.7 6.2 1.4 0.8 0.6 0.5 0.7 0.4 0.9 2.2 2.5 1.9 1.4 2.4 2.4 9.1 12.8 12.2 0.7 27.3 4.7 21.5 2.4 0.0 6.7 68.9 34.5 3.5 107.2 9.1 35.0 108.4 14.2 230.3 96.2 7.9 44.5 1011.9 43.8 3.3 7.7 9.1 76.3 2.3 66.7 1.2 22.0 99.4 37.5 94.9 8.7 18.5 235.7 65.9 1.7 19.0 52.9 61.1 132.6 63.3 351.0 7.5 141.3 16.0 47.8 63.4 14.0 114.4 0.5 1.1 18.7 37.5 5.3 148.3 21.5 87.1 65.2 16.1 121.8 0.0 3.9 3.5 25.5 11.4 1.2 3.8 7.3 112.1 82.7 43.7 6.5 ITK "EMT, LYK, PSCTK2" ENSG00000113263 "IL2 inducible T cell kinase" Q08881 5 157142933-157255185 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Adaptive immunity, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "lymphoid tissue: 57.9" "Group enriched" "Detected in some" 6 "dendritic cells: 51.7;granulocytes: 31.8;NK-cells: 42.2;Plasma cells: 34.0;T-cells: 115.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 23 "gdT-cell: 39.6;MAIT T-cell: 26.4;memory CD4 T-cell: 55.6;memory CD8 T-cell: 54.9;naive CD4 T-cell: 78.2;naive CD8 T-cell: 65.0;NK-cell: 29.3;T-reg: 73.2" "Group enriched" "Detected in many" 23 "NK-cells: 29.3;T-cells: 78.2" "Group enriched" "Detected in some" 10 "JURKAT: 62.2;MOLT-4: 23.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA043670 Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane, Cytosol" "HPA043670: " "unprognostic (2.08e-3)" "unprognostic (6.57e-4)" "unprognostic (5.06e-3)" "unprognostic (4.96e-5)" "unprognostic (1.52e-2)" "unprognostic (1.12e-4)" "unprognostic (8.45e-4)" "unprognostic (1.56e-2)" "unprognostic (1.87e-2)" "unprognostic (5.99e-3)" "unprognostic (1.76e-1)" "unprognostic (2.52e-1)" "unprognostic (4.52e-6)" "unprognostic (3.64e-1)" "unprognostic (4.42e-2)" "unprognostic (1.46e-1)" "unprognostic (3.26e-2)" 1.0 0.3 0.0 15.9 0.0 3.7 0.9 0.0 0.0 1.0 0.0 1.4 0.7 0.4 0.0 1.4 0.4 4.2 0.2 0.0 0.0 0.3 1.6 3.1 29.3 0.0 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.4 1.5 0.0 0.3 0.1 0.0 0.2 4.0 0.5 0.0 10.5 3.1 0.5 0.0 57.9 0.5 0.0 24.6 3.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 3.9 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 62.2 0.0 0.0 0.0 0.0 23.7 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.1 0.0 39.6 0.0 26.4 0.0 55.6 54.9 0.1 0.0 78.2 65.0 1.3 29.3 2.3 0.1 73.2 44.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 6.2 0.0 4.0 2.7 0.6 0.0 0.0 0.0 0.4 0.4 0.9 0.0 0.6 1.8 0.0 0.1 51.7 0.1 0.0 0.1 8.5 0.2 0.3 0.8 0.0 1.7 0.2 0.0 0.0 1.1 7.7 0.4 31.8 0.1 1.8 1.0 0.0 0.0 0.2 0.0 0.0 1.6 5.1 6.7 0.0 2.9 1.8 1.0 2.8 0.0 42.2 0.0 0.1 0.0 0.0 0.0 34.0 0.3 0.0 0.4 0.0 0.0 0.0 1.0 1.0 0.0 0.0 0.2 3.4 0.1 115.7 0.0 0.1 0.6 IYD "C6orf71, DEHAL1, dJ422F24.1" ENSG00000009765 "Iodotyrosine deiodinase" Q6PHW0 6 150368892-150405969 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" Oxidoreductase "Congenital hypothyroidism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "thyroid gland: 472.7" "Cell type enhanced" "Detected in some" "Distal enterocytes: 23.7;Hepatocytes: 25.1;Intestinal goblet cells: 21.8;Paneth cells: 22.5;Proximal enterocytes: 89.1;Proximal tubular cells: 35.4" "Cancer enriched" "Detected in many" 20 "thyroid cancer: 80.7" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "neutrophil: 1.9" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 7 "CACO-2: 1.3;OE19: 3.0;SK-BR-3: 3.2" "Group enriched" "Detected in some" 13 "hippocampal formation: 7.4;thalamus: 2.4" "Low region specificity" "Detected in all" HPA059627 Enhanced Supported "Plasma membrane" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 1: Thyroid gland - Transcription" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "HPA059627: AB_2684086" "unprognostic (3.73e-4)" "unprognostic (2.93e-2)" "unprognostic (5.97e-2)" "unprognostic (1.95e-2)" "unprognostic (1.55e-1)" "unprognostic (2.98e-2)" "prognostic favorable (6.22e-4)" "unprognostic (1.11e-1)" "unprognostic (3.80e-2)" "unprognostic (1.17e-1)" "unprognostic (7.41e-2)" "unprognostic (1.02e-1)" "unprognostic (3.07e-9)" "unprognostic (9.79e-3)" "unprognostic (2.04e-1)" "unprognostic (2.03e-2)" "unprognostic (2.18e-2)" 0.1 0.0 0.4 0.6 0.3 0.3 0.5 0.6 0.6 0.1 0.2 6.4 18.1 0.2 0.6 0.0 0.0 8.9 0.5 0.3 0.1 26.6 33.6 0.7 0.5 0.5 0.4 0.0 0.4 0.0 0.0 0.0 0.6 0.2 6.5 0.2 0.1 0.0 0.0 0.2 19.6 0.2 0.0 0.1 2.0 0.2 0.5 0.0 472.7 0.0 0.2 0.1 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 1.3 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.1 3.0 0.1 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.0 3.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 1.6 0.5 0.3 0.2 0.4 0.2 0.2 0.1 0.1 0.0 0.4 0.2 0.2 1.9 0.7 0.2 0.3 0.2 1.3 0.4 0.3 0.6 0.6 0.3 0.1 0.5 0.4 0.6 0.0 0.5 0.5 0.7 3.2 7.8 0.0 0.0 0.1 0.6 0.2 0.0 0.1 0.3 0.4 0.8 14.3 8.9 0.0 0.0 0.1 0.0 23.7 1.9 0.3 0.0 0.9 0.3 0.4 3.6 2.7 0.1 0.2 0.0 0.7 0.0 2.2 1.3 0.1 1.1 25.1 0.1 0.0 0.1 21.8 0.0 0.0 1.2 0.1 0.0 0.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.4 22.5 0.0 0.0 1.0 89.1 35.4 3.6 1.3 0.0 1.7 0.3 0.1 0.1 0.0 0.4 0.3 0.9 0.4 11.5 0.7 JPH2 JP-2 ENSG00000149596 "Junctophilin 2" Q9BR39 20 44106590-44187188 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 85.2;skeletal muscle: 120.4" "Cell type enriched" "Detected in some" 4 "Cardiomyocytes: 64.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 15.3;EFO-21: 15.0;fHDF/TERT166: 19.1;HeLa: 12.6;SiHa: 12.9" "Low region specificity" "Detected in some" HPA052646 Approved NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 20: HeLa - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA052646: AB_2681899" "unprognostic (1.57e-1)" "unprognostic (1.82e-2)" "unprognostic (2.61e-4)" "unprognostic (4.71e-2)" "unprognostic (1.48e-1)" "unprognostic (2.32e-2)" "unprognostic (1.06e-2)" "unprognostic (2.45e-3)" "unprognostic (6.87e-2)" "unprognostic (9.16e-2)" "unprognostic (2.57e-2)" "unprognostic (9.73e-2)" "unprognostic (4.76e-2)" "unprognostic (5.45e-2)" "unprognostic (2.10e-1)" "unprognostic (2.67e-1)" "unprognostic (1.10e-2)" 6.0 1.9 0.5 4.5 0.6 0.1 5.7 0.4 0.7 15.1 0.7 63.3 2.1 51.6 2.9 11.9 30.0 3.5 85.2 0.4 0.5 1.4 0.3 5.2 0.2 1.1 1.1 3.9 0.3 0.1 1.2 3.8 0.8 23.8 4.5 0.2 5.8 22.1 120.4 3.8 11.8 27.5 0.9 1.3 16.0 0.8 0.6 0.1 1.5 48.3 0.1 40.5 10.6 0.7 7.5 0.8 0.4 0.0 0.3 0.4 1.5 2.2 4.1 5.4 2.3 15.3 5.9 0.0 15.0 19.1 6.1 10.5 0.0 0.5 2.1 0.0 0.0 0.0 12.6 0.1 0.1 0.3 0.0 0.7 1.1 2.7 3.7 3.3 0.0 0.0 0.0 0.0 7.3 4.3 0.0 0.2 0.3 0.0 0.9 1.7 3.4 0.0 0.4 0.1 0.0 0.1 12.9 3.1 0.1 8.6 10.8 0.1 0.3 2.4 2.7 0.5 4.7 0.1 0.0 0.0 0.2 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.4 0.7 0.4 0.5 1.1 1.1 0.8 0.9 0.6 0.7 0.2 0.0 0.0 0.3 0.0 6.6 0.5 0.9 0.0 0.0 0.4 5.1 64.6 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.9 0.0 0.0 0.8 0.0 0.5 2.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.8 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.1 0.2 0.2 0.0 6.6 15.9 12.8 0.0 1.5 0.0 2.0 0.5 0.1 0.0 0.2 0.1 KAT6A "MOZ, MYST3, RUNXBP2, ZC2HC6A, ZNF220" ENSG00000083168 "Lysine acetyltransferase 6A" Q92794 8 41929479-42051994 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Acyltransferase, Chromatin regulator, Repressor, Transferase" "Cancer-related genes, Mental retardation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017023, HPA063266, HPA065052" Supported Supported "Nucleoli,Nuclear speckles,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Nuclear speckles" "Nucleoli, Cytosol" "CAB017023: , HPA063266: AB_2684973, HPA065052: AB_2685414" "unprognostic (3.51e-2)" "unprognostic (1.14e-1)" "unprognostic (2.04e-1)" "unprognostic (3.23e-2)" "unprognostic (2.28e-1)" "unprognostic (9.27e-3)" "unprognostic (3.61e-1)" "unprognostic (2.29e-1)" "unprognostic (2.95e-1)" "unprognostic (2.45e-2)" "unprognostic (1.50e-1)" "unprognostic (4.45e-2)" "unprognostic (4.20e-3)" "unprognostic (1.18e-1)" "unprognostic (2.24e-1)" "unprognostic (8.58e-2)" "unprognostic (2.95e-2)" 14.4 7.1 8.6 15.4 12.7 38.2 12.3 20.1 10.5 13.7 9.7 10.2 9.6 15.6 8.6 13.4 12.0 11.2 9.1 9.1 12.8 9.1 10.0 16.7 16.8 12.7 12.4 21.5 11.7 18.0 6.7 14.9 12.9 11.0 10.6 18.1 9.6 9.7 13.1 16.6 12.1 13.5 8.2 15.7 11.3 11.4 10.1 27.0 14.2 16.0 17.2 12.0 10.7 16.7 19.6 23.2 34.8 21.8 17.8 20.3 9.8 15.4 20.6 17.9 14.2 16.3 11.5 33.4 13.4 19.0 19.5 17.3 27.3 18.6 23.2 16.1 14.4 60.4 14.2 10.3 14.8 27.3 23.6 17.1 19.1 20.4 24.8 14.5 18.8 29.7 36.6 24.2 16.0 10.4 59.9 9.4 12.8 20.4 8.1 37.7 39.1 9.9 11.0 27.1 17.6 16.7 15.8 12.4 13.8 15.8 26.3 12.9 25.5 21.6 15.3 21.1 15.5 16.8 22.1 33.8 12.6 14.1 17.3 2.5 0.8 1.8 1.6 0.9 1.6 1.4 1.6 2.1 0.6 1.6 1.9 1.8 5.1 1.9 0.9 1.1 1.9 1.2 8.6 12.7 20.1 10.5 9.1 12.8 12.7 12.4 12.9 8.2 10.1 16.7 87.5 35.3 34.9 64.0 54.0 50.3 24.2 15.5 18.2 54.8 31.7 25.5 23.7 18.6 25.3 12.9 54.2 14.4 61.5 23.2 3.9 14.2 2.6 30.3 47.5 56.7 24.7 31.2 62.8 11.8 17.0 32.4 21.4 44.8 35.4 31.9 43.5 25.3 17.0 58.9 76.6 24.9 10.2 44.2 34.5 4.8 28.3 43.7 23.2 120.9 30.3 27.9 61.8 93.5 129.2 15.7 20.2 23.0 38.7 30.7 22.9 10.6 22.8 44.9 19.7 49.3 34.6 37.8 37.0 23.0 61.2 21.1 61.4 19.7 19.3 27.2 KAZALD1 "FKSG28, FKSG40" ENSG00000107821 "Kazal type serine peptidase inhibitor domain 1" Q96I82 10 101061989-101068131 "Predicted secreted proteins" "Differentiation, Osteogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 18.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 23.0;Gastric mucus-secreting cells: 44.4;Intestinal goblet cells: 53.5;Proximal enterocytes: 78.1" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 30.8;T-47d: 36.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA011800 Uncertain "Secreted to extracellular matrix" NA NA 65000 "Cluster 64: Macrophages - Immune response" "Cluster 6: T47d - Mammary gland" "Cluster 27: Mucus-secreting cells - Mucin production" "HPA011800: AB_1852082" "unprognostic (3.34e-1)" "unprognostic (8.86e-3)" "unprognostic (1.16e-2)" "unprognostic (4.43e-3)" "unprognostic (4.88e-2)" "unprognostic (1.35e-2)" "unprognostic (6.68e-3)" "unprognostic (2.62e-1)" "unprognostic (1.39e-2)" "unprognostic (1.70e-2)" "unprognostic (1.35e-1)" "unprognostic (1.38e-1)" "unprognostic (1.26e-1)" "unprognostic (3.44e-3)" "unprognostic (6.35e-2)" "prognostic unfavorable (5.10e-4)" "unprognostic (2.11e-1)" 2.9 0.6 0.3 0.6 0.2 0.3 2.8 0.3 0.4 7.1 0.1 1.9 2.8 2.0 1.3 0.6 2.1 0.6 8.1 0.5 0.2 2.0 0.5 1.2 0.7 0.4 0.3 0.5 0.9 0.8 3.6 0.8 0.4 5.2 1.6 0.4 6.9 2.2 4.1 1.7 3.2 1.5 0.2 18.0 6.6 1.9 0.4 1.0 2.5 3.1 0.3 3.6 2.9 0.2 3.3 1.6 1.8 30.8 1.8 7.4 2.0 5.2 5.6 1.0 1.0 6.2 2.0 0.2 2.8 4.6 0.5 0.7 1.9 0.1 0.3 3.1 0.8 0.4 6.5 6.7 0.5 0.4 2.3 1.1 0.4 0.1 0.9 0.4 0.0 0.9 0.7 3.2 0.9 5.3 0.1 1.9 0.5 7.2 11.7 12.4 9.1 0.4 0.6 1.6 0.3 1.2 0.5 0.8 1.7 0.7 36.7 0.5 0.1 0.7 2.1 0.5 1.2 0.9 2.6 2.5 1.3 3.5 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.3 0.4 0.5 0.2 0.4 0.3 0.4 0.2 0.4 0.2 8.3 0.0 1.5 0.7 0.3 2.0 0.9 1.6 0.6 1.5 2.5 3.0 3.4 1.5 1.6 0.0 2.1 0.3 0.3 23.0 1.9 0.5 0.1 4.1 1.3 5.1 2.4 2.7 0.1 2.1 0.6 16.9 44.4 7.2 0.0 0.2 3.6 0.3 0.8 0.0 0.1 53.5 4.1 4.8 1.9 0.1 9.9 0.9 1.8 0.0 0.0 0.8 0.0 0.0 0.1 1.5 12.8 0.4 0.2 5.0 78.1 0.4 0.7 2.2 0.0 10.4 6.1 3.9 1.4 0.7 2.8 0.5 0.6 0.2 8.1 0.4 KCNA3 "HLK3, HPCN3, Kv1.3, MK3" ENSG00000177272 "Potassium voltage-gated channel subfamily A member 3" P22001 1 110672465-110674940 "FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 25.4" "Cell type enhanced" "Detected in some" "Excitatory neurons: 13.1;Inhibitory neurons: 60.2;Plasma cells: 61.6;T-cells: 20.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "B-cells: 4.9;T-cells: 14.3" "Cell line enhanced" "Detected in some" "HDLM-2: 23.1;Karpas-707: 45.6;U-266/70: 32.6;U-266/84: 31.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016625 Approved NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 58: T-cells - T-cell receptor" "HPA016625: AB_2669407" "unprognostic (2.17e-2)" "unprognostic (5.07e-3)" "unprognostic (3.92e-3)" "unprognostic (1.20e-2)" "unprognostic (2.35e-1)" "unprognostic (1.76e-5)" "unprognostic (1.70e-4)" "unprognostic (8.48e-2)" "unprognostic (1.49e-2)" "unprognostic (5.92e-4)" "unprognostic (1.81e-2)" "unprognostic (3.96e-2)" "unprognostic (1.39e-1)" "unprognostic (3.13e-2)" "unprognostic (2.99e-2)" "unprognostic (1.73e-1)" "unprognostic (1.40e-1)" 0.5 0.9 3.4 6.4 2.0 4.6 0.9 1.1 4.9 1.1 0.0 2.4 2.5 0.5 0.0 0.5 0.3 1.3 0.4 5.0 7.2 0.2 0.8 5.9 9.4 1.1 3.3 0.7 0.4 0.4 0.4 0.7 5.0 0.5 1.9 0.6 1.4 0.2 0.1 0.2 2.6 0.6 0.2 6.0 4.3 0.5 3.3 25.4 0.7 0.1 7.6 2.6 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.0 8.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.5 0.0 45.6 0.0 0.0 10.0 0.0 0.9 0.0 0.0 0.0 0.0 9.6 0.0 0.0 6.3 0.5 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.7 0.0 0.0 32.6 31.9 11.6 0.0 2.7 0.0 0.0 1.1 0.0 8.9 0.0 10.0 2.8 13.4 14.3 1.4 4.9 10.4 7.9 0.0 1.3 0.1 0.6 13.4 4.4 3.4 2.0 1.1 4.9 5.0 7.2 1.1 3.3 5.0 0.2 3.3 0.0 0.2 0.0 1.9 1.3 11.5 0.4 0.0 0.0 0.0 2.5 0.1 0.0 0.6 0.0 0.0 1.8 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 1.3 13.1 0.0 0.0 0.7 1.5 0.0 0.0 0.0 1.8 0.0 0.4 0.0 60.2 0.0 0.0 1.6 2.4 0.0 0.0 3.1 3.6 2.8 2.4 0.3 3.1 7.5 1.3 0.0 0.0 0.0 61.6 0.0 0.0 0.1 0.0 0.2 6.6 0.0 0.1 4.3 0.9 0.1 0.6 0.0 20.3 0.0 0.0 0.1 KCNH2 "erg1, HERG, Kv11.1, LQT2" ENSG00000055118 "Potassium voltage-gated channel subfamily H member 2" Q12809 7 150944961-150978321 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Deafness, Disease variant, FDA approved drug targets, Long QT syndrome, Short QT syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 42.3;pituitary gland: 43.3" "Group enriched" "Detected in many" 4 "Bipolar cells: 217.3;Cardiomyocytes: 83.2;Erythroid cells: 76.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "K-562: 197.7;NB-4: 97.8;SH-SY5Y: 78.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 1: K-562 - Erythropoiesis" "Cluster 56: Bipolar cells - Visual perception" "unprognostic (2.22e-1)" "unprognostic (1.75e-2)" "unprognostic (1.06e-2)" "prognostic unfavorable (6.06e-5)" "unprognostic (9.79e-3)" "unprognostic (1.95e-2)" "unprognostic (3.40e-2)" "unprognostic (3.84e-2)" "unprognostic (3.53e-2)" "unprognostic (3.52e-1)" "prognostic favorable (5.61e-4)" "unprognostic (6.08e-2)" "unprognostic (2.26e-2)" "unprognostic (4.90e-2)" "unprognostic (2.83e-1)" "unprognostic (6.24e-2)" "unprognostic (3.02e-2)" 0.8 3.7 9.8 2.6 8.0 42.3 0.1 13.5 9.0 4.4 4.4 36.1 2.7 16.9 1.7 1.5 7.3 3.2 29.6 5.6 14.8 1.1 0.2 2.0 0.3 23.5 14.7 3.2 3.4 18.1 43.3 1.4 23.0 9.8 1.0 6.7 1.1 8.0 0.2 0.3 8.3 7.8 6.3 1.8 10.9 30.8 17.1 0.4 0.2 0.0 0.1 12.9 2.7 4.1 0.0 0.3 0.9 4.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 8.0 2.9 0.0 0.2 0.0 3.1 0.0 0.0 0.8 0.4 18.3 0.0 0.0 0.2 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 4.4 197.7 0.0 0.0 0.9 1.6 97.8 1.3 0.2 0.0 0.1 0.1 10.1 0.0 0.0 3.8 78.2 0.0 0.1 0.0 1.1 0.0 1.8 0.6 0.0 1.5 0.0 0.0 5.3 0.2 2.1 0.0 11.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 8.0 13.5 9.0 5.6 14.8 23.5 14.7 23.0 6.3 17.1 4.1 0.0 0.0 0.0 1.6 1.6 0.0 0.2 0.1 0.0 217.3 0.4 0.3 83.2 0.0 0.0 0.0 4.2 0.2 0.0 0.0 0.0 2.1 2.0 0.5 0.8 0.9 16.3 76.4 5.2 0.2 0.9 5.0 0.5 0.1 26.1 6.3 1.4 0.1 0.3 16.8 13.9 0.7 12.2 0.0 0.3 4.8 2.5 0.0 0.0 2.8 0.0 4.5 0.0 5.5 1.7 0.3 0.0 13.2 1.4 0.1 0.2 0.1 0.4 10.3 0.0 1.7 2.6 2.5 5.1 0.0 0.0 0.3 0.9 0.7 0.3 0.4 KCTD14 MGC2376 ENSG00000151364 "Potassium channel tetramerization domain containing 14" Q9BQ13 11 78015715-78046191 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast glandular cells: 13.7;Breast myoepithelial cells: 12.8;Exocrine glandular cells: 17.1;Gastric mucus-secreting cells: 14.3;Intestinal goblet cells: 20.8;Prostatic glandular cells: 14.3;Proximal tubular cells: 15.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 26.1;Hep G2: 29.0;RPTEC TERT1: 45.9;U-2 OS: 20.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041118, HPA042181" Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 30: Mammary glandular cells - Lactation" Nucleoplasm "Vesicles, Cytosol" "HPA041118: AB_10963117, HPA042181: AB_10968059" "unprognostic (7.37e-3)" "unprognostic (4.27e-2)" "unprognostic (7.03e-2)" "unprognostic (6.93e-2)" "unprognostic (1.59e-2)" "unprognostic (2.28e-2)" "unprognostic (2.04e-3)" "unprognostic (3.26e-1)" "prognostic unfavorable (3.96e-5)" "prognostic favorable (8.01e-4)" "prognostic unfavorable (1.05e-4)" "unprognostic (3.19e-1)" "prognostic favorable (6.92e-5)" "unprognostic (2.42e-2)" "unprognostic (2.05e-1)" "prognostic favorable (5.93e-4)" "unprognostic (1.63e-1)" 3.4 23.1 2.0 1.6 2.0 0.1 20.4 5.1 2.9 10.4 3.2 8.1 4.9 3.4 14.3 1.5 11.7 6.7 0.6 2.1 2.1 11.5 10.3 8.2 0.3 1.9 2.3 0.8 27.2 8.3 2.5 1.3 2.2 7.0 11.9 1.6 28.7 19.1 0.2 1.9 5.2 2.1 1.6 0.6 20.8 0.6 2.5 1.3 15.9 0.6 0.5 2.3 1.4 1.7 0.0 3.5 0.6 0.5 1.3 0.8 3.5 1.8 1.6 3.4 8.4 13.5 8.8 0.1 9.3 1.1 0.4 1.0 0.6 26.1 8.9 0.5 13.2 0.0 3.0 29.0 4.9 0.2 0.1 4.0 0.7 13.9 11.0 2.5 1.0 0.2 0.3 0.1 1.4 0.2 0.3 0.8 6.5 0.5 0.5 0.4 0.0 0.0 45.9 3.5 2.3 0.2 0.0 0.2 4.5 0.8 1.4 1.1 0.8 0.2 20.2 0.7 0.4 0.3 0.2 0.2 0.2 0.2 3.7 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.3 0.2 0.0 0.1 0.3 0.0 0.2 0.2 0.2 0.0 0.0 2.0 2.0 5.1 2.9 2.1 2.1 1.9 2.3 2.2 1.6 2.5 1.7 0.6 3.2 10.8 0.0 0.2 0.4 12.2 2.0 2.8 0.4 13.7 12.8 0.0 1.5 4.1 5.5 0.0 0.6 0.3 5.2 3.9 2.6 0.3 2.7 2.0 0.9 4.8 0.0 0.0 17.1 1.3 1.1 14.3 3.7 1.3 0.5 0.0 4.8 0.2 0.0 0.0 20.8 0.0 0.0 0.0 0.0 3.4 0.4 1.8 0.0 0.1 2.1 0.0 0.0 0.0 10.5 6.6 5.3 0.0 14.3 2.2 15.1 0.1 0.0 0.0 0.0 1.8 0.2 0.3 0.7 0.1 0.7 0.3 0.7 8.5 7.4 KCTD17 FLJ12242 ENSG00000100379 "Potassium channel tetramerization domain containing 17" Q8N5Z5 22 37051736-37063390 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Ubl conjugation pathway" "Disease variant, Dystonia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 113.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 4 "basal ganglia: 90.8" HPA018459 Uncertain NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 65: Brain - Ion transport" "Cluster 17: WM-115 - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA018459: AB_1852169" "unprognostic (1.09e-2)" "unprognostic (2.33e-1)" "unprognostic (1.09e-1)" "unprognostic (1.61e-2)" "unprognostic (5.38e-2)" "unprognostic (3.09e-3)" "prognostic unfavorable (3.59e-5)" "unprognostic (1.89e-1)" "unprognostic (4.90e-2)" "unprognostic (2.19e-1)" "prognostic favorable (4.22e-5)" "unprognostic (8.62e-2)" "prognostic unfavorable (5.13e-12)" "unprognostic (2.32e-1)" "unprognostic (1.57e-1)" "unprognostic (2.32e-1)" "unprognostic (6.94e-2)" 8.2 15.6 64.8 9.8 113.7 2.4 6.7 46.0 71.6 14.2 44.4 15.9 3.4 14.9 1.8 7.2 10.7 8.5 26.6 68.0 54.1 5.8 3.5 9.3 10.6 44.8 70.4 13.7 3.7 7.8 43.0 6.5 52.4 11.2 5.2 3.6 3.4 9.0 1.7 21.1 10.4 9.4 43.8 11.1 7.9 46.0 83.8 7.0 7.6 3.0 6.9 16.9 13.0 55.5 15.9 20.5 31.7 23.7 14.9 14.8 1.2 16.2 15.6 25.9 22.3 4.4 4.6 12.2 10.9 20.8 20.3 4.2 10.0 19.0 10.9 23.8 26.8 5.2 5.6 4.9 22.1 0.0 6.1 17.3 9.2 26.6 5.8 17.5 33.6 15.9 1.2 13.2 16.5 12.8 11.0 0.3 20.3 9.4 17.4 19.8 8.4 3.6 6.7 4.1 26.4 32.9 15.0 14.1 7.5 6.6 3.8 4.2 19.6 33.5 31.2 16.0 12.0 17.7 5.5 2.0 29.6 7.3 18.6 0.0 0.8 0.0 0.9 1.0 0.9 1.2 0.6 0.9 0.9 0.4 0.8 0.6 0.0 1.6 0.4 0.2 1.0 0.4 64.8 113.7 46.0 71.6 68.0 54.1 44.8 70.4 52.4 43.8 83.8 55.5 8.8 0.0 0.5 11.1 5.8 1.5 4.6 2.8 1.2 17.3 1.3 1.5 5.0 4.3 0.8 5.5 2.1 0.4 5.0 17.7 0.0 11.9 24.9 0.7 12.7 9.7 13.1 0.8 22.4 6.1 2.8 9.9 4.1 0.9 4.5 12.0 12.8 0.5 9.2 13.5 11.6 5.3 0.0 9.6 17.0 28.1 10.5 9.8 3.6 1.9 13.0 16.4 8.2 4.5 7.1 3.2 16.0 9.1 4.6 1.2 0.5 2.5 1.5 7.8 0.0 7.8 11.7 19.7 7.1 1.3 4.8 7.5 8.5 10.2 7.0 2.4 KDM1B "AOF1, bA204B7.3, C6orf193, dJ298J15.2, FLJ33898, FLJ34109, FLJ43328, LSD2" ENSG00000165097 "Lysine demethylase 1B" Q8NB78 6 18155329-18223854 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Developmental protein, Oxidoreductase, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "dendritic cells: 3.7;granulocytes: 7.2;monocytes: 8.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031269, HPA055597" Uncertain Supported Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 21: OE19 - Mitochondria" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm "HPA031269: AB_10601587, HPA055597: " "unprognostic (1.93e-1)" "unprognostic (7.53e-2)" "prognostic favorable (6.94e-4)" "unprognostic (2.57e-2)" "unprognostic (7.25e-2)" "unprognostic (1.08e-1)" "unprognostic (5.57e-3)" "unprognostic (1.32e-2)" "unprognostic (8.41e-2)" "unprognostic (6.84e-2)" "unprognostic (2.16e-1)" "unprognostic (3.17e-2)" "unprognostic (6.68e-2)" "unprognostic (3.02e-2)" "unprognostic (2.90e-1)" "unprognostic (7.36e-2)" "unprognostic (3.53e-1)" 5.9 7.6 5.6 11.4 7.6 27.2 6.3 5.3 7.8 7.6 7.6 14.1 8.0 5.7 3.7 9.1 13.4 6.0 6.8 6.6 5.9 7.8 7.4 8.8 10.4 6.9 6.7 6.7 5.9 3.2 5.8 4.6 6.1 5.2 12.2 12.0 5.7 4.7 17.3 11.2 8.9 6.9 6.2 10.5 5.6 15.7 5.6 10.8 27.2 9.1 9.4 7.7 8.1 9.4 15.1 9.7 11.2 23.0 13.8 20.5 24.5 11.7 12.6 7.5 10.2 16.3 7.4 34.1 31.6 19.2 22.8 15.5 17.8 20.8 16.0 31.6 14.6 17.2 8.6 15.0 6.7 25.5 17.5 10.3 23.4 21.5 17.7 12.1 7.7 15.9 38.3 5.2 12.7 12.6 14.1 10.5 3.8 31.6 12.8 26.8 20.3 24.4 10.7 19.8 34.2 10.6 9.7 23.5 22.9 11.7 22.3 20.3 6.5 16.9 9.5 11.9 15.5 5.2 15.9 20.0 6.4 18.9 37.8 1.2 4.6 7.2 0.5 8.6 0.3 1.2 0.5 0.5 3.7 1.3 0.5 0.2 4.9 0.3 6.9 1.6 0.7 1.3 5.6 7.6 5.3 7.8 6.6 5.9 6.9 6.7 6.1 6.2 5.6 9.4 4.9 0.0 8.2 14.7 8.7 12.7 5.7 3.8 7.4 5.0 7.6 6.6 10.4 11.5 10.4 1.8 10.4 2.7 3.0 23.0 1.9 6.6 0.7 36.2 10.0 4.2 6.7 3.8 19.0 4.3 5.1 5.8 8.2 15.5 2.5 3.3 4.2 7.7 7.5 5.0 10.8 9.6 10.2 36.7 11.7 0.7 3.7 20.6 7.2 22.5 27.7 6.6 8.2 16.1 23.8 7.2 21.2 6.8 3.7 5.4 6.2 11.2 21.0 15.5 0.0 6.9 6.2 0.7 18.2 9.7 15.9 1.4 5.6 3.1 10.6 6.6 KDM2B "CXXC2, Fbl10, FBXL10, JHDM1B, PCCX2" ENSG00000089094 "Lysine demethylase 2B" Q8NHM5 12 121429096-121581023 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Chromatin regulator, Dioxygenase, DNA-binding, Oxidoreductase, Repressor, RNA-binding, rRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071257 Supported Nucleoplasm NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 5: NTERA-2 - Transcription" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "HPA071257: " "unprognostic (7.67e-2)" "unprognostic (3.72e-3)" "unprognostic (2.15e-1)" "unprognostic (1.69e-1)" "unprognostic (1.37e-1)" "prognostic favorable (6.74e-6)" "unprognostic (1.16e-1)" "unprognostic (5.45e-2)" "unprognostic (1.01e-2)" "unprognostic (1.95e-1)" "prognostic favorable (8.64e-4)" "unprognostic (1.77e-1)" "unprognostic (4.44e-3)" "unprognostic (1.44e-2)" "unprognostic (3.90e-2)" "unprognostic (7.07e-2)" "unprognostic (4.82e-2)" 9.7 8.4 7.1 18.9 8.7 16.9 10.0 12.9 10.7 15.6 7.4 12.2 8.2 11.5 5.5 20.2 12.4 7.0 8.7 7.3 5.6 11.1 15.6 13.1 22.9 8.3 6.3 15.2 11.6 10.8 9.4 7.3 9.2 9.5 7.6 9.7 12.6 6.1 15.2 28.0 18.9 8.3 5.4 21.4 10.9 14.0 7.8 23.1 11.2 6.1 21.6 12.3 16.9 9.0 15.2 19.1 31.3 9.8 8.7 7.6 34.8 12.4 19.1 17.8 14.9 24.0 7.7 69.3 20.6 11.2 9.9 13.1 34.3 13.7 14.4 29.3 24.0 38.0 15.9 19.4 10.3 44.0 29.5 6.9 7.4 16.9 12.3 19.1 12.7 33.6 31.4 8.8 8.5 20.4 54.5 51.8 55.8 11.0 15.1 61.0 16.4 34.1 9.8 24.5 37.1 21.4 23.8 14.0 14.4 29.5 25.0 49.2 17.3 19.0 15.4 19.2 13.9 23.9 21.3 64.5 17.6 35.2 12.3 4.5 2.8 2.4 6.3 2.3 4.9 9.5 4.9 3.5 3.9 9.3 4.3 5.8 0.4 2.0 1.7 3.5 4.6 3.4 7.1 8.7 12.9 10.7 7.3 5.6 8.3 6.3 9.2 5.4 7.8 9.0 6.8 0.0 10.6 28.1 36.8 17.0 7.1 4.0 13.6 20.1 10.3 6.7 14.6 14.3 5.4 11.0 12.5 6.7 43.3 3.8 11.7 7.5 57.0 13.0 7.0 8.8 5.4 22.5 36.2 5.8 11.2 8.3 9.2 12.0 14.0 16.5 9.7 15.4 24.4 15.2 41.6 6.1 6.1 21.1 61.0 60.1 7.8 25.5 16.0 26.2 48.0 4.1 24.7 31.2 44.1 5.8 4.7 7.2 34.1 11.2 6.5 4.2 5.7 16.1 19.7 6.5 8.1 11.4 18.3 13.9 15.2 6.6 24.8 6.2 7.4 6.3 KDM5A "JARID1A, RBBP2" ENSG00000073614 "Lysine demethylase 5A" P29375 12 280057-389320 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, Dioxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 45.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006201 Supported "Nuclear bodies,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 5: NTERA-2 - Transcription" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nuclear bodies" Cytosol "HPA006201: AB_1079160" "unprognostic (2.75e-1)" "unprognostic (1.68e-1)" "unprognostic (1.83e-1)" "unprognostic (1.12e-1)" "unprognostic (4.46e-2)" "unprognostic (1.60e-1)" "unprognostic (3.53e-3)" "unprognostic (1.81e-2)" "unprognostic (5.81e-2)" "unprognostic (3.19e-1)" "unprognostic (1.77e-3)" "unprognostic (6.11e-2)" "unprognostic (1.79e-2)" "unprognostic (1.10e-1)" "unprognostic (1.52e-1)" "unprognostic (2.60e-2)" "unprognostic (7.69e-2)" 8.1 8.7 5.8 11.4 8.3 45.5 11.1 11.6 8.5 8.6 10.0 8.2 7.2 9.7 7.1 8.9 7.6 8.0 5.2 6.2 6.5 7.8 9.9 8.8 15.3 6.8 5.7 11.0 9.4 10.1 4.2 11.8 6.5 8.6 9.9 9.6 6.7 7.3 5.5 12.5 7.3 9.4 6.0 13.5 8.8 21.1 6.7 21.6 9.1 7.6 14.4 8.7 7.2 15.0 14.4 25.3 18.3 14.2 16.1 15.2 20.3 12.5 16.5 18.4 19.8 15.2 17.0 24.0 3.9 21.0 16.0 13.3 19.2 14.2 21.9 37.9 15.9 29.3 26.5 9.0 13.0 38.6 22.1 16.6 13.1 22.6 29.9 18.8 18.8 21.0 17.9 32.7 15.7 9.7 27.9 11.0 28.4 12.3 7.9 25.7 47.5 11.4 8.8 32.6 7.0 20.5 24.5 11.0 13.0 25.0 11.9 24.0 26.0 12.0 17.0 13.6 21.1 11.5 13.6 53.7 15.5 16.5 18.0 64.5 21.8 44.4 31.4 25.0 32.3 27.1 24.6 25.9 22.8 32.0 26.3 22.8 63.0 35.8 28.9 32.0 20.9 22.5 5.8 8.3 11.6 8.5 6.2 6.5 6.8 5.7 6.5 6.0 6.7 15.0 53.1 64.1 61.6 61.7 80.6 33.0 22.2 30.1 48.9 69.0 35.3 27.9 38.2 31.5 39.0 35.0 116.7 48.8 103.3 51.3 3.9 37.4 96.8 60.2 72.8 51.6 69.7 51.3 71.7 31.6 34.7 47.2 39.8 99.8 54.4 106.9 42.8 30.9 30.2 87.5 59.1 40.0 40.7 52.5 37.5 32.5 48.4 63.9 26.6 57.1 82.9 48.3 105.0 68.3 85.9 38.7 37.0 55.7 73.1 32.4 33.6 11.8 40.2 71.9 59.2 64.0 59.9 137.1 104.8 50.1 47.6 71.1 80.1 67.5 40.1 42.0 KIAA1522 ENSG00000162522 KIAA1522 Q9P206 1 32741830-32774970 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 154.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 125.7;hTCEpi: 103.0;RT4: 117.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032050, HPA032051, HPA064839" Approved Supported "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cell Junctions" Nucleoplasm "HPA032050: AB_10601764, HPA032051: AB_2674126, HPA064839: AB_2685366" "unprognostic (7.98e-2)" "unprognostic (1.14e-2)" "unprognostic (1.44e-2)" "unprognostic (3.09e-2)" "unprognostic (6.41e-2)" "unprognostic (3.63e-3)" "prognostic unfavorable (6.29e-7)" "unprognostic (1.58e-1)" "unprognostic (1.13e-1)" "unprognostic (5.06e-2)" "prognostic unfavorable (8.25e-5)" "unprognostic (4.55e-2)" "prognostic favorable (1.29e-5)" "unprognostic (1.35e-2)" "unprognostic (1.35e-1)" "unprognostic (3.98e-1)" "unprognostic (2.12e-1)" 7.9 93.0 14.6 7.0 10.7 1.2 24.3 1.8 15.6 14.5 27.1 42.5 51.7 10.1 12.2 76.7 23.5 16.0 5.1 12.4 6.5 43.9 12.0 18.2 1.2 5.2 5.5 22.3 70.7 37.8 9.1 8.4 4.3 40.9 30.9 1.2 68.3 20.2 3.1 74.1 45.9 6.7 4.2 1.4 61.8 5.1 7.7 8.2 39.4 3.2 12.1 22.2 28.1 8.8 65.7 33.6 5.4 9.3 2.4 4.6 24.6 7.9 15.3 8.9 8.7 37.0 125.7 0.2 32.3 11.6 26.5 95.1 10.3 67.8 4.6 0.2 13.4 13.6 49.4 30.4 4.0 0.2 33.3 1.7 103.0 23.6 28.2 40.1 18.6 2.7 20.1 0.4 4.3 54.3 0.3 0.6 11.0 56.3 20.9 8.7 6.7 16.7 85.8 117.5 4.6 4.7 49.5 70.1 9.7 33.7 74.7 4.3 17.6 14.9 39.3 13.7 17.3 0.8 0.3 0.3 15.2 2.3 17.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 10.7 1.8 15.6 12.4 6.5 5.2 5.5 4.3 4.2 7.7 8.8 5.7 12.8 56.9 5.5 0.6 73.9 37.0 52.7 59.2 0.6 69.8 42.3 3.8 72.9 52.0 27.6 2.1 15.6 1.5 154.4 9.8 47.3 4.2 54.7 5.6 8.7 28.9 1.3 10.2 66.7 5.2 6.7 51.0 50.2 27.8 10.2 4.6 10.6 2.9 0.0 5.2 54.0 48.8 0.8 6.5 5.1 8.7 2.2 7.2 3.7 2.4 0.8 0.0 2.0 0.4 60.7 64.6 4.9 0.3 80.9 84.7 14.8 60.7 0.1 6.6 3.1 7.5 3.8 2.7 59.7 83.1 7.9 2.1 59.9 65.4 99.6 KIF11 "Eg5, HKSP, KNSL1, TRIP5" ENSG00000138160 "Kinesin family member 11" P52732 10 92574105-92655395 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Motor protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 19.4;lymphoid tissue: 37.9" "Cell type enhanced" "Detected in many" "Erythroid cells: 39.1;Granulosa cells: 20.7;Spermatocytes: 38.0;Spermatogonia: 23.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA006916, HPA010093, HPA010568, CAB017617" Enhanced Supported "Mitotic spindle,Cytosol" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "Mitotic spindle" "CAB017617: AB_2131098, HPA006916: AB_1848033, HPA010093: AB_2668281, HPA010568: AB_1848034" "unprognostic (1.53e-1)" "unprognostic (1.11e-2)" "unprognostic (1.59e-2)" "unprognostic (3.35e-2)" "unprognostic (2.12e-1)" "unprognostic (7.82e-2)" "prognostic unfavorable (8.19e-7)" "prognostic unfavorable (3.27e-4)" "unprognostic (1.24e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (2.30e-4)" "unprognostic (6.59e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.35e-3)" "unprognostic (7.23e-2)" "unprognostic (9.08e-2)" "unprognostic (2.01e-1)" 1.1 0.7 0.5 8.5 0.7 19.4 2.5 0.4 0.6 1.4 0.5 6.3 5.5 1.8 1.0 6.7 1.0 1.2 0.6 0.5 0.5 1.0 1.1 1.3 17.5 0.6 0.6 0.6 0.5 0.7 0.3 3.9 0.6 1.0 7.4 0.8 1.3 0.7 0.2 6.0 5.3 2.5 0.5 2.9 3.9 11.6 0.4 37.9 1.6 0.3 18.5 2.3 2.3 0.6 103.1 45.2 100.6 94.5 7.3 10.5 24.2 72.6 62.8 78.8 78.1 39.6 67.2 111.1 36.5 34.4 32.9 72.0 72.1 36.5 92.4 68.3 41.3 70.5 41.4 42.4 1.4 116.0 63.0 3.6 3.3 61.4 55.9 18.3 50.0 46.1 51.2 126.4 61.1 41.4 99.3 65.8 40.3 42.5 30.7 106.6 98.8 40.2 21.0 30.1 30.0 42.9 56.4 25.9 29.2 34.1 67.9 37.6 28.6 35.7 51.3 37.1 96.9 35.4 58.3 113.4 29.5 82.3 50.3 0.8 0.0 0.1 0.0 0.3 0.3 0.6 0.4 0.4 0.2 0.1 0.1 0.2 0.2 1.0 0.1 0.1 1.1 0.2 0.5 0.7 0.4 0.6 0.5 0.5 0.6 0.6 0.6 0.5 0.4 0.6 0.4 0.0 2.0 1.3 3.5 2.9 1.1 1.6 3.4 1.0 1.8 1.8 1.7 1.5 2.5 1.8 0.0 6.7 2.3 2.9 1.9 0.5 16.3 3.4 4.3 2.0 0.0 39.1 2.1 0.6 11.4 4.7 9.2 4.9 0.0 20.7 2.2 0.4 8.2 0.0 1.8 4.3 4.1 4.6 3.4 4.4 0.9 4.0 0.0 0.0 1.0 0.7 2.1 2.5 1.1 0.2 0.4 0.7 15.2 0.8 0.5 0.6 3.7 0.4 0.0 1.7 3.7 38.0 23.4 12.6 3.3 1.5 4.5 2.5 8.0 1.7 KIF13B "GAKIN, KIAA0639" ENSG00000197892 "Kinesin family member 13B" Q9NQT8 8 29067278-29263124 "Plasma proteins, Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "brain: 64.5;parathyroid gland: 161.5" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 140.2;Oligodendrocytes: 371.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025023, HPA049655" Enhanced NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 44: Endometrium - Transcription" "HPA025023: AB_1852471, HPA049655: AB_2732555" "unprognostic (1.37e-1)" "unprognostic (4.31e-1)" "prognostic favorable (8.92e-4)" "unprognostic (1.35e-3)" "unprognostic (2.27e-1)" "prognostic favorable (6.26e-4)" "unprognostic (1.04e-1)" "unprognostic (1.66e-1)" "unprognostic (1.21e-2)" "unprognostic (9.69e-2)" "prognostic unfavorable (4.77e-4)" "unprognostic (9.76e-2)" "prognostic favorable (0.00e+0)" "unprognostic (1.19e-1)" "unprognostic (1.81e-1)" "unprognostic (1.76e-1)" "unprognostic (2.27e-1)" 7.4 11.7 25.9 6.8 47.6 5.1 9.2 34.9 30.6 8.7 16.6 18.3 16.1 6.7 9.4 8.4 7.1 8.4 5.3 20.0 29.4 18.5 10.2 8.5 4.3 47.3 43.7 7.2 10.9 161.5 10.0 3.8 42.1 10.9 13.8 7.9 15.6 8.5 4.7 20.0 15.7 5.5 29.3 8.9 19.2 6.6 40.1 5.1 9.0 3.0 4.6 9.5 6.1 64.5 12.4 13.2 4.6 3.8 7.5 4.3 6.7 0.7 2.9 3.9 6.2 8.3 6.9 2.6 6.9 0.8 7.1 8.2 3.7 2.1 5.1 3.9 3.6 6.6 1.8 8.4 7.2 1.8 19.2 5.0 3.9 8.9 3.6 8.3 17.1 4.9 8.6 9.5 12.9 3.8 9.7 3.1 2.3 17.4 2.2 5.5 10.6 4.9 17.0 13.2 1.3 9.1 2.4 8.0 11.7 4.8 5.9 3.7 22.8 2.8 7.6 0.8 5.6 6.9 11.1 4.4 16.4 3.4 13.2 0.1 1.5 1.7 1.5 1.1 0.7 1.4 0.6 0.9 0.5 0.8 0.5 0.6 0.7 0.9 0.6 2.2 0.6 0.5 25.9 47.6 34.9 30.6 20.0 29.4 47.3 43.7 42.1 29.3 40.1 64.5 22.2 44.8 24.8 30.0 16.5 4.5 13.8 17.2 5.2 13.3 23.5 11.2 5.3 20.0 36.8 35.0 60.5 6.4 35.8 95.8 11.7 25.7 8.0 55.3 12.7 14.2 25.2 7.4 26.7 25.0 0.9 10.0 55.0 140.2 41.0 10.6 13.9 18.6 8.9 16.8 35.3 44.1 36.7 25.7 6.3 3.5 8.1 24.4 7.2 41.2 12.1 9.5 12.3 47.3 371.1 39.7 58.0 20.3 42.5 28.1 34.7 17.8 34.9 26.2 6.6 36.4 7.4 6.3 7.7 9.8 6.8 5.1 31.8 5.9 36.0 32.5 KIF1C "SAX2, SPAX2, SPG58" ENSG00000129250 "Kinesin family member 1C" O43896 17 4997950-5028401 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Motor protein" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "brain: 244.8;choroid plexus: 142.7;heart muscle: 185.0;skeletal muscle: 561.0;tongue: 389.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 315.4;Distal enterocytes: 168.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024602, HPA045020" Approved NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA024602: AB_1852480, HPA045020: AB_2679187" "unprognostic (3.89e-2)" "unprognostic (3.73e-2)" "unprognostic (2.70e-2)" "unprognostic (1.24e-2)" "unprognostic (3.74e-1)" "unprognostic (8.97e-2)" "unprognostic (1.92e-1)" "unprognostic (2.28e-1)" "unprognostic (6.69e-2)" "unprognostic (8.31e-2)" "unprognostic (1.45e-1)" "unprognostic (4.90e-3)" "prognostic favorable (2.26e-9)" "unprognostic (1.10e-1)" "unprognostic (2.28e-1)" "unprognostic (1.41e-1)" "unprognostic (7.10e-3)" 54.6 18.6 200.1 25.1 230.9 6.3 36.3 184.0 210.0 33.9 142.7 63.3 53.3 44.4 7.9 75.7 31.5 28.0 185.0 164.4 175.0 37.9 46.4 49.6 10.0 219.0 216.9 24.1 51.6 55.1 10.5 18.6 197.0 36.4 33.2 4.3 38.3 36.7 561.0 53.4 51.4 36.3 200.7 26.5 51.2 17.7 200.8 11.3 38.7 389.2 16.7 51.4 37.3 244.8 104.1 97.6 32.2 69.4 74.5 44.5 51.0 80.8 64.3 63.2 38.3 70.7 24.5 16.6 46.7 127.2 41.2 105.3 58.4 107.2 44.6 40.2 68.7 12.0 124.1 57.4 50.7 4.9 34.6 46.0 109.9 85.2 58.0 59.6 87.2 14.5 45.9 28.4 62.6 61.5 14.7 8.0 25.1 68.1 63.4 15.1 54.1 17.2 55.7 71.9 7.8 15.3 114.2 63.0 34.9 30.6 62.0 14.9 185.5 84.8 63.7 62.2 99.3 10.8 9.9 8.9 62.6 20.9 43.0 0.5 0.4 0.7 0.2 0.4 0.2 0.4 0.2 0.2 0.3 0.4 0.2 0.2 1.2 0.3 0.2 0.2 0.3 0.1 200.1 230.9 184.0 210.0 164.4 175.0 219.0 216.9 197.0 200.7 200.8 244.8 24.8 54.5 50.6 6.5 6.8 16.8 19.0 25.6 12.5 12.5 24.8 14.2 315.4 48.6 28.1 25.8 0.0 14.8 6.5 168.9 19.6 32.2 71.6 13.0 15.1 37.8 14.4 4.4 5.7 43.1 14.0 21.9 51.0 29.3 12.7 21.6 37.1 82.7 16.1 23.5 7.3 77.3 12.2 18.5 11.0 32.1 16.8 11.9 16.0 10.3 16.1 7.7 6.2 4.5 5.0 63.0 83.8 42.5 11.4 44.1 92.9 42.9 18.4 5.8 6.6 35.0 35.1 18.7 23.6 21.3 20.2 23.3 7.9 12.4 65.4 36.6 KIF20B "CT90, KRMP1, MPHOSPH1, MPP1" ENSG00000138182 "Kinesin family member 20B" Q96Q89 10 89701590-89774939 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Motor protein" Oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 10.2;lymphoid tissue: 9.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 89.2;Spermatocytes: 165.4;Spermatogonia: 96.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA050214 Supported Supported "Nucleoplasm,Cytokinetic bridge,Midbody,Cytosol" Yes Yes "Cluster 6: Non-specific - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cytokinetic bridge" "Midbody, Cytosol" "HPA050214: AB_2681053" "unprognostic (2.13e-1)" "unprognostic (3.01e-2)" "unprognostic (1.72e-2)" "unprognostic (3.20e-2)" "unprognostic (2.65e-1)" "unprognostic (7.39e-2)" "unprognostic (8.95e-5)" "unprognostic (3.32e-3)" "unprognostic (2.01e-2)" "unprognostic (8.14e-2)" "prognostic unfavorable (1.21e-4)" "unprognostic (1.62e-2)" "prognostic unfavorable (3.06e-6)" "unprognostic (4.22e-3)" "unprognostic (2.70e-1)" "unprognostic (2.51e-2)" "unprognostic (6.43e-2)" 1.3 0.7 0.3 4.5 1.0 10.2 2.5 2.4 0.4 1.5 0.1 3.2 3.6 2.3 0.4 3.3 1.2 1.3 0.9 0.3 0.3 1.3 1.3 1.5 8.0 0.5 0.3 2.7 0.7 1.1 0.2 2.4 0.6 1.3 4.0 1.1 1.0 0.9 0.4 2.5 3.4 2.2 0.4 3.3 2.5 6.9 0.6 9.8 1.8 0.7 7.5 1.6 0.7 0.6 84.8 17.0 24.3 21.7 4.7 8.0 20.2 33.8 30.9 34.8 36.3 22.6 38.1 32.5 10.4 17.3 13.0 41.8 27.3 18.9 46.4 39.5 18.6 33.1 30.5 19.5 1.4 57.1 26.3 3.4 2.8 33.7 33.9 12.2 22.8 17.0 32.2 36.5 31.3 14.6 33.6 10.8 25.0 13.8 16.1 23.1 47.8 14.3 10.7 11.2 7.7 13.9 24.4 11.0 12.2 17.3 28.5 16.3 17.9 22.2 22.1 29.1 55.3 10.1 29.5 43.2 21.1 49.4 16.8 13.1 2.4 4.2 5.5 4.1 6.8 13.0 7.4 6.1 1.3 16.0 8.6 8.0 0.2 3.0 4.5 5.2 9.5 2.2 0.3 1.0 2.4 0.4 0.3 0.3 0.5 0.3 0.6 0.4 0.6 0.6 11.5 3.2 13.5 2.3 36.4 17.7 6.2 20.8 6.8 14.3 8.3 8.5 8.7 1.5 10.7 0.0 10.4 21.4 32.3 8.8 3.9 6.9 13.1 10.6 13.2 11.0 1.2 89.2 8.1 4.7 38.1 13.2 14.8 12.9 44.4 37.2 9.3 4.4 20.7 13.5 9.5 8.6 16.2 21.0 17.9 10.5 8.1 17.1 5.4 23.4 11.3 7.5 24.7 9.0 9.1 4.1 5.7 8.6 51.4 3.7 8.9 3.2 6.6 9.8 6.6 16.9 17.1 165.4 96.7 26.1 14.1 5.2 34.2 12.9 25.5 5.2 KIF24 "bA571F15.4, C9orf48, FLJ10933, FLJ43884" ENSG00000186638 "Kinesin family member 24" Q5T7B8 9 34252381-34311371 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Motor protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 11.1" "Cell type enhanced" "Detected in some" "Astrocytes: 32.3;Early spermatids: 28.9;Late spermatids: 41.6;Spermatocytes: 14.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 19 "basophil: 2.8" "Lineage enriched" "Detected in single" 19 "granulocytes: 2.8" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA020643 Uncertain NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 64: Astrocytes - Nervous system maintenance" "HPA020643: AB_2131749" "unprognostic (2.68e-1)" "prognostic favorable (1.33e-4)" "unprognostic (9.44e-2)" "unprognostic (3.82e-3)" "unprognostic (3.11e-1)" "unprognostic (2.11e-3)" "unprognostic (1.40e-2)" "unprognostic (8.38e-3)" "unprognostic (1.53e-2)" "unprognostic (2.48e-2)" "unprognostic (1.40e-2)" "unprognostic (8.68e-3)" "unprognostic (1.17e-1)" "unprognostic (1.30e-3)" "unprognostic (2.28e-1)" "unprognostic (1.25e-1)" "unprognostic (2.50e-1)" 0.2 0.6 0.7 0.9 1.0 2.1 0.7 0.6 0.7 0.6 4.4 0.9 0.6 0.6 1.4 0.9 3.2 0.4 0.5 0.8 0.8 0.9 0.3 0.6 1.3 1.9 2.3 0.4 0.5 1.5 1.0 0.6 1.3 0.4 1.0 0.4 0.3 0.5 0.7 0.9 0.6 0.7 1.5 0.3 0.6 11.1 0.8 3.9 1.2 0.6 1.6 0.3 0.4 0.8 9.8 6.4 7.5 6.2 0.6 1.0 2.8 5.3 3.4 7.0 8.4 3.1 3.0 7.6 1.6 2.5 4.5 4.5 7.6 4.6 7.2 4.9 3.3 3.5 10.7 1.9 0.2 7.2 5.3 0.4 0.9 9.1 3.8 1.3 3.2 5.3 3.6 6.0 3.9 4.0 8.7 6.7 3.0 4.5 3.8 8.0 4.6 2.1 2.9 2.5 3.5 3.4 6.5 3.3 0.9 2.9 3.6 3.5 2.6 6.5 7.1 5.1 6.5 1.7 2.9 4.1 4.4 3.5 8.6 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.7 1.0 0.6 0.7 0.8 0.8 1.9 2.3 1.3 1.5 0.8 0.8 0.3 0.0 1.1 32.3 0.7 0.4 0.2 0.7 0.6 0.3 0.7 1.1 0.9 1.5 1.6 1.8 0.0 0.6 0.3 0.7 0.0 0.4 28.9 8.2 0.8 0.4 0.0 3.0 7.2 0.2 1.0 0.7 2.0 0.8 0.0 1.5 0.0 0.0 0.7 0.0 3.5 0.8 2.0 0.3 0.3 41.6 0.9 0.4 0.0 3.7 0.1 0.2 0.0 10.1 9.2 0.2 0.0 1.9 2.1 0.1 0.3 0.4 11.0 0.4 0.0 0.5 0.4 14.5 6.9 1.0 0.9 0.3 0.3 0.8 0.7 0.1 KLHL25 "ENC-2, ENC2, FLJ12587" ENSG00000183655 "Kelch like family member 25" Q9H0H3 15 85759326-85794925 "Predicted intracellular proteins" "Translation regulation, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Horizontal cells: 13.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 3.8" "Group enriched" "Detected in many" 4 "monocytes: 3.8;NK-cells: 2.5;T-cells: 1.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "cerebral cortex: 29.1;hippocampal formation: 16.3" HPA023450 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 15: Liver - Metabolism" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA023450: AB_1852583" "unprognostic (1.18e-1)" "unprognostic (1.06e-2)" "unprognostic (2.78e-2)" "unprognostic (1.99e-2)" "unprognostic (1.30e-1)" "unprognostic (1.42e-1)" "unprognostic (2.94e-2)" "unprognostic (8.98e-2)" "unprognostic (6.60e-2)" "unprognostic (9.29e-3)" "unprognostic (4.25e-2)" "unprognostic (5.18e-2)" "unprognostic (2.22e-2)" "unprognostic (3.57e-2)" "unprognostic (1.80e-1)" "unprognostic (2.08e-1)" "unprognostic (2.66e-2)" 6.5 2.4 5.6 2.6 7.6 0.5 5.4 5.8 7.5 4.3 4.3 3.8 4.7 6.6 3.1 5.7 4.0 2.2 3.9 6.0 7.6 3.7 15.1 4.3 1.9 5.4 8.2 3.3 1.6 2.2 3.6 1.1 6.9 4.6 1.1 0.8 3.6 3.1 6.5 9.3 3.4 2.8 4.7 1.6 5.0 10.5 7.6 2.0 2.4 3.0 1.3 3.7 5.0 6.7 2.7 8.1 11.6 5.7 2.3 1.2 6.0 3.4 1.6 4.6 3.5 10.9 4.4 1.7 1.7 2.8 2.9 6.6 12.5 6.4 1.0 1.7 5.8 0.5 3.5 8.4 2.7 0.5 2.0 2.4 2.1 4.5 1.5 2.0 2.5 5.8 0.7 1.5 2.0 5.0 4.3 2.6 10.5 4.6 4.2 8.7 6.9 2.8 1.7 5.6 16.1 11.1 4.9 5.6 2.2 4.7 10.2 0.6 2.1 4.9 8.9 3.2 6.2 1.6 3.7 1.7 2.2 3.0 2.8 0.0 0.1 0.2 1.0 1.2 0.5 0.0 1.0 0.7 0.2 0.2 1.7 1.1 0.0 2.5 3.8 0.6 0.9 0.5 5.6 7.6 5.8 7.5 6.0 7.6 5.4 8.2 6.9 4.7 7.6 6.7 0.8 0.0 1.9 3.6 1.2 2.7 4.0 2.1 0.0 3.3 4.0 2.8 4.3 1.5 1.5 0.0 0.0 1.0 3.6 6.3 1.9 2.3 13.0 3.0 3.6 1.8 10.7 0.0 7.7 2.7 1.5 2.4 8.6 3.2 0.0 2.0 2.2 12.4 0.8 13.5 4.1 7.6 4.1 1.3 2.7 4.6 0.9 1.4 7.2 1.0 0.6 2.7 2.1 6.0 0.9 5.3 3.1 1.5 1.3 2.7 2.7 2.1 2.1 1.1 6.6 2.9 2.9 3.3 4.1 4.4 4.7 1.8 4.0 1.4 5.2 4.3 KLK5 "KLK-L2, SCTE" ENSG00000167754 "Kallikrein related peptidase 5" Q9Y337 19 50943303-50953093 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "skin 1: 202.7" "Group enriched" "Detected in some" 4 "Early spermatids: 85.4;Late spermatids: 193.2" "Group enriched" "Detected in many" 5 "head and neck cancer: 73.1;melanoma: 32.1;ovarian cancer: 112.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 41 "A-431: 485.1;HaCaT: 455.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA014343, CAB025503, CAB026341, HPA073512" Enhanced "Secreted in other tissues" NA NA 2500000 "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 25: Spermatids - Spermatogenesis" "CAB025503: , CAB026341: , HPA014343: AB_1852603, HPA073512: " "unprognostic (3.19e-2)" "unprognostic (1.06e-1)" "prognostic unfavorable (2.33e-4)" "unprognostic (4.30e-4)" "unprognostic (3.01e-1)" "prognostic unfavorable (9.79e-4)" "unprognostic (3.04e-1)" "unprognostic (3.05e-1)" "unprognostic (1.70e-3)" "unprognostic (2.21e-1)" "unprognostic (2.76e-1)" "unprognostic (2.53e-1)" "unprognostic (9.16e-3)" "prognostic unfavorable (3.85e-6)" 4.6 0.0 1.1 0.0 1.1 0.0 30.2 0.4 2.6 15.6 0.6 0.0 0.1 0.1 0.0 23.0 0.5 0.0 0.2 1.1 0.8 0.5 0.1 6.1 0.0 1.0 1.0 0.0 0.0 0.0 0.1 0.0 1.0 0.2 0.0 0.0 23.6 0.0 1.1 202.7 0.0 0.0 0.5 0.3 0.0 14.2 1.6 0.1 0.1 0.0 0.6 0.0 13.5 0.7 485.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 0.0 0.0 0.0 0.1 455.4 0.0 1.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.1 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 1.3 0.0 0.0 1.1 0.0 1.5 0.1 0.4 0.3 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.1 0.4 2.6 1.1 0.8 1.0 1.0 1.0 0.5 1.6 0.7 0.2 16.0 0.0 0.0 0.0 26.8 1.8 2.4 12.0 0.0 33.0 27.2 0.3 0.0 0.8 0.0 0.0 0.0 1.0 0.0 0.0 0.0 85.4 0.0 0.0 0.8 0.0 0.0 0.5 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 193.2 1.2 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 1.1 0.0 0.0 0.5 0.0 0.0 0.0 0.1 1.6 0.8 2.8 10.9 0.0 0.3 0.0 0.0 0.1 KLRF2 NKp65 ENSG00000256797 "Killer cell lectin like receptor F2" D3W0D1 12 9881489-9895833 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 13 "skin 1: 11.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 32 "NK-cell: 3.1;plasmacytoid DC: 3.2" "Group enriched" "Detected in many" 32 "dendritic cells: 3.2;NK-cells: 3.1" "Cell line enriched" "Detected in single" 47 "U-937: 31.5" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (1.04e-1)" "unprognostic (1.25e-1)" "unprognostic (6.24e-2)" "unprognostic (1.63e-1)" "unprognostic (5.57e-2)" "unprognostic (3.40e-5)" "unprognostic (9.03e-2)" "unprognostic (3.16e-1)" 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.7 0.1 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 11.9 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 31.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 KRT14 "EBS3, EBS4" ENSG00000186847 "Keratin 14" P02533 17 41582279-41586895 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Ectodermal dysplasia, Epidermolysis bullosa, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 6940.5" "Group enriched" "Detected in many" 9 "Basal keratinocytes: 35588.3;Suprabasal keratinocytes: 11677.1" "Cancer enriched" "Detected in many" 5 "head and neck cancer: 5910.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 4065.2;HBEC3-KT: 2003.9;hTCEpi: 2448.6;hTERT-HME1: 794.2;U-2197: 696.0" "Not detected" "Not detected" "Region enriched" "Detected in many" 7 "spinal cord: 36.3" "CAB000134, HPA000452, HPA000539, HPA023040" Enhanced Enhanced "Intermediate filaments" NA NA 1600000000 "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "Intermediate filaments" "CAB000134: , HPA000452: AB_1079177, HPA000539: , HPA023040: AB_1852201" "prognostic favorable (2.66e-4)" "unprognostic (1.64e-1)" "unprognostic (1.01e-2)" "unprognostic (1.42e-2)" "unprognostic (1.66e-1)" "unprognostic (1.02e-2)" "unprognostic (2.03e-2)" "unprognostic (2.74e-1)" "unprognostic (1.35e-1)" "unprognostic (1.00e-2)" "unprognostic (5.74e-3)" "unprognostic (1.49e-8)" "unprognostic (8.91e-2)" "unprognostic (2.00e-1)" "unprognostic (8.80e-3)" "unprognostic (1.22e-2)" 15.8 1.2 0.0 0.0 0.0 2.7 332.7 0.0 0.0 412.0 0.0 1.7 0.0 0.9 0.0 1304.2 1.7 0.0 3.5 0.0 0.0 0.8 2.5 1.7 0.0 0.0 0.0 1.3 2.9 0.0 4.3 2.2 0.1 29.1 0.0 0.0 702.1 3.8 15.9 6940.5 2.1 0.1 0.0 0.9 1.7 1.5 0.0 186.7 2.3 0.0 262.3 0.7 846.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.8 0.1 0.0 0.3 0.0 0.0 0.0 0.6 0.1 0.7 0.0 4065.2 0.0 2003.9 0.2 0.0 0.0 0.1 1.6 0.0 0.1 0.2 2.5 0.1 2448.6 3.0 794.2 0.0 0.1 0.0 0.5 3.6 0.0 0.0 0.2 0.2 0.0 0.2 0.0 0.6 0.2 0.6 0.0 0.1 0.1 0.0 0.2 0.5 0.0 0.0 0.4 0.0 0.3 9.1 1.7 696.0 0.0 0.9 0.0 0.0 3.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 8.3 0.0 0.0 0.0 0.5 35588.3 1072.7 181.5 2407.4 0.0 103.5 740.9 0.3 0.0 6.0 0.0 0.0 17.9 3.2 7.3 0.0 0.1 0.0 0.1 0.0 129.0 0.0 0.0 0.0 0.0 127.0 116.5 0.0 0.2 0.0 0.0 0.0 0.0 3.3 0.0 0.0 3.4 0.0 0.0 1833.4 0.0 0.0 9.3 1990.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 3.5 0.0 9.9 702.0 96.8 0.0 2.3 0.0 0.0 0.0 96.3 0.0 0.1 83.2 11677.1 2.5 62.1 0.1 2.3 100.0 KRT18 ENSG00000111057 "Keratin 18" P05783 12 52948871-52952906 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Host-virus interaction" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 3698.8;Ductal cells: 6583.8;Exocrine glandular cells: 4826.1;Extravillous trophoblasts: 5496.7;Pancreatic endocrine cells: 6071.5;Syncytiotrophoblasts: 7643.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "basophil: 76.7" "Lineage enriched" "Detected in many" 7 "granulocytes: 76.7" "Cell line enhanced" "Detected in many" "A549: 5639.4;BEWO: 3818.0;CACO-2: 6249.4;CAPAN-2: 4576.4;MCF7: 8470.0;SK-BR-3: 4583.8" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 12.1" "CAB000008, CAB000030, HPA001605" Enhanced Supported Cytosol NA NA 140000000 "Cluster 38: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 1: Pancreatic cells - Digestion" Cytosol "CAB000008: , CAB000030: , HPA001605: AB_2666381" "unprognostic (1.98e-1)" "unprognostic (1.03e-1)" "unprognostic (3.31e-1)" "unprognostic (1.63e-2)" "unprognostic (1.25e-1)" "unprognostic (7.26e-3)" "unprognostic (4.09e-3)" "prognostic unfavorable (5.06e-4)" "unprognostic (8.81e-2)" "unprognostic (4.17e-1)" "prognostic unfavorable (1.78e-4)" "unprognostic (3.05e-1)" "unprognostic (1.04e-1)" "unprognostic (1.27e-1)" "unprognostic (2.19e-1)" "unprognostic (1.11e-2)" "unprognostic (1.13e-2)" 170.3 29.0 2.6 77.5 1.4 1.5 209.8 5.3 1.6 243.5 34.8 424.1 324.3 27.8 226.0 118.4 193.5 180.6 38.3 2.2 6.9 247.2 519.5 177.8 8.6 26.1 4.3 16.4 570.2 79.5 251.9 474.5 30.3 183.3 492.3 0.6 323.4 129.5 2.1 44.5 370.7 23.4 2.5 28.5 289.9 8.3 13.9 10.3 244.1 1.4 27.8 199.7 62.2 2.5 2065.1 5639.4 1.1 7.9 0.7 1.1 3818.0 313.3 349.5 368.4 104.6 6249.4 4576.4 1.4 839.8 318.4 196.5 487.2 79.1 2228.5 217.9 2.6 138.2 19.4 865.7 1743.9 942.1 0.6 1.3 13.6 202.9 323.8 437.1 1046.9 399.0 3.4 511.4 0.2 0.3 8470.0 3.8 37.3 471.0 2740.1 457.9 3.0 0.3 236.1 1803.3 1144.9 65.6 3.7 512.7 4583.8 18.8 2696.0 2446.8 6.6 137.9 5.0 441.8 6.9 68.3 1.1 7.3 4.3 0.9 1.2 36.4 76.7 0.3 2.4 0.6 0.2 2.2 4.6 4.5 1.2 2.2 7.4 11.1 4.1 3.2 2.5 0.0 0.1 0.4 2.9 2.6 1.4 5.3 1.6 2.2 6.9 26.1 4.3 30.3 2.5 13.9 2.5 14.4 862.2 286.4 0.3 29.8 14.8 1605.7 912.1 447.3 0.1 814.6 615.6 5.3 1252.5 877.3 623.5 0.0 3698.8 14.2 1942.9 275.9 6583.8 1.0 462.3 60.3 77.8 642.3 15.4 0.0 4826.1 5496.7 203.5 971.5 742.4 48.9 51.2 57.1 610.9 308.3 1.7 0.0 2492.6 1969.3 9.8 13.8 3.8 10.5 28.3 208.1 1.0 41.5 6.2 0.0 0.0 0.0 6071.5 2164.1 0.0 13.7 1205.1 1912.3 718.5 500.8 0.6 0.0 0.6 298.6 2.7 26.0 395.7 6.7 7643.5 38.1 45.0 1635.0 1512.1 KRT25 KRT25A ENSG00000204897 "Keratin 25" Q7Z3Z0 17 40748021-40755331 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Hypotrichosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 42 "skin 1: 112.3" "Cell type enhanced" "Detected in some" "Early spermatids: 7.8;Late spermatids: 9.2;Spermatogonia: 2.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "RPTEC TERT1: 1.3" "Region enriched" "Detected in some" 7 "cerebellum: 8.6" "Group enriched" "Detected in some" 5 "cerebral cortex: 7.3;hippocampal formation: 4.8" "HPA053977, HPA058943" Enhanced Approved Vesicles NA NA "Cluster 61: Skin - Cornification" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 34: Spermatids - Unknown function" Vesicles "HPA053977: AB_2682329, HPA058943: AB_2683859" "unprognostic (8.19e-2)" "unprognostic (5.89e-8)" "unprognostic (1.79e-1)" 2.6 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 112.3 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KRT28 KRT25D ENSG00000173908 "Keratin 28" Q7Z3Y7 17 40792196-40799959 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 15 "skin 1: 11.7" "Cell type enhanced" "Detected in single" "Spermatogonia: 1.3" "Cancer enhanced" "Detected in some" "cervical cancer: 0.6;endometrial cancer: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 6 "cerebellum: 3.2" "Not detected" "Not detected" HPA066890 Enhanced NA NA "Cluster 61: Skin - Cornification" "Cluster 25: Spermatids - Spermatogenesis" "HPA066890: AB_2685742" 0.3 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KRT4 "CK4, CYK4, K4" ENSG00000170477 "Keratin 4" P19013 12 52806549-52814116 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "esophagus: 19735.6" "Cell type enriched" "Detected in some" 18 "Squamous epithelial cells: 5828.7" "Group enriched" "Detected in many" 5 "cervical cancer: 94.3;head and neck cancer: 151.8;stomach cancer: 73.1;urothelial cancer: 38.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 33 "HaCaT: 734.9;SK-BR-3: 361.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB002154, HPA034881" Enhanced Supported "Intermediate filaments" NA NA 600000000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments" "CAB002154: AB_563803, HPA034881: AB_2674370" "unprognostic (4.04e-1)" "unprognostic (3.22e-3)" "unprognostic (5.16e-3)" "unprognostic (8.52e-3)" "unprognostic (1.20e-1)" "unprognostic (2.64e-1)" "unprognostic (1.84e-1)" "prognostic unfavorable (3.26e-4)" "unprognostic (2.85e-3)" "unprognostic (2.84e-2)" "unprognostic (2.58e-11)" "unprognostic (1.64e-1)" "unprognostic (6.97e-2)" "unprognostic (1.16e-1)" "prognostic unfavorable (6.26e-4)" 1.5 1.5 0.0 0.0 0.0 0.0 0.9 0.0 0.0 513.5 0.0 1.1 0.0 1.2 0.0 19735.6 9.5 3.1 7.2 0.0 0.0 0.9 2.6 17.3 0.0 0.0 0.0 1.8 2.8 0.0 8.9 0.0 0.0 4.3 0.0 0.0 2124.1 0.0 2.6 3.9 1.7 0.9 0.0 1.5 8.6 0.8 0.0 2.0 1.0 0.1 1418.0 4.4 1040.2 0.0 0.0 16.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 1.8 0.0 0.1 0.0 734.9 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.5 1.3 0.0 0.9 0.0 0.0 0.0 0.0 0.0 1.9 0.3 0.0 1.4 0.0 0.2 0.0 15.5 0.0 0.1 0.3 0.0 0.0 0.0 0.2 0.0 1.0 361.6 0.0 0.0 2.0 0.0 2.0 0.0 0.2 0.0 0.0 0.0 1.0 0.9 0.5 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.4 3.3 0.0 0.0 0.0 6.5 36.9 23.3 0.0 0.5 2.9 0.5 0.0 308.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.6 0.2 2.9 0.0 0.0 0.0 0.0 0.0 2.6 0.0 1.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 28.5 0.0 0.0 0.1 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 9.9 6.9 0.0 0.1 53.7 0.0 0.0 0.0 5.3 0.0 0.1 5828.7 0.0 0.0 2.0 0.0 0.0 54.4 KRT71 "K6IRS1, KRT6IRS, KRT6IRS1" ENSG00000139648 "Keratin 71" Q3SY84 12 52543909-52553145 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Hypotrichosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "skin 1: 100.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "endometrial cancer: 0.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 15 "CACO-2: 6.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA049404 Enhanced NA NA 110000000 "Cluster 61: Skin - Cornification" "Cluster 39: CACO-2 - Unknown function" "Cluster 65: Plasmacytoid DCs - Unknown function" "HPA049404: AB_2680748" "unprognostic (9.12e-2)" "unprognostic (2.38e-1)" "unprognostic (1.21e-1)" "unprognostic (1.04e-1)" "unprognostic (1.51e-1)" "unprognostic (2.18e-1)" "unprognostic (1.47e-1)" "unprognostic (3.14e-1)" "unprognostic (1.69e-2)" 2.3 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 100.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 KRT74 "K6IRS4, KRT5C, KRT6IRS4" ENSG00000170484 "Keratin 74" Q7RTS7 12 52565782-52573843 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Ectodermal dysplasia, Hypotrichosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "epididymis: 5.6;skin 1: 16.3" "Cell type enriched" "Detected in some" 5 "Late spermatids: 5.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA040655, HPA048596" Enhanced Approved "Nucleoli,Intermediate filaments,Cytosol" NA NA 130000000 "Cluster 61: Skin - Cornification" "Cluster 31: Spermatids - Spermatogenesis" "Intermediate filaments" "Nucleoli, Cytosol" "HPA040655: , HPA048596: AB_2680457" "unprognostic (6.75e-3)" "unprognostic (3.93e-1)" "unprognostic (1.60e-1)" "unprognostic (2.49e-2)" "unprognostic (9.46e-2)" "unprognostic (2.29e-1)" "unprognostic (8.54e-2)" "unprognostic (1.02e-1)" 0.2 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 KRT76 "HUMCYT2A, KRT2B, KRT2P" ENSG00000185069 "Keratin 76" Q01546 12 52768155-52777345 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "lymphoid tissue: 2.5;salivary gland: 2.6" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 12 "head and neck cancer: 1.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA019656, HPA019696" Approved NA NA 310000000 "Cluster 16: Immune cells - Immune response" "Cluster 31: Spermatids - Spermatogenesis" "HPA019656: AB_1852241, HPA019696: AB_1852243" "unprognostic (2.00e-1)" "unprognostic (1.89e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KRTAP1-1 "HB2A, KAP1.1, KAP1.1A, KAP1.1B" ENSG00000188581 "Keratin associated protein 1-1" Q07627 17 41040541-41041450 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 329 "skin 1: 81.3" "Group enriched" "Detected in some" 6 "Basal prostatic cells: 7.5;Ductal cells: 6.0;Prostatic glandular cells: 2.3;Urothelial cells: 2.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" "Cluster 22: Epithelial cell types - Mixed function" "unprognostic (2.90e-1)" 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 81.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 KRTAP1-3 KAP1.3 ENSG00000221880 "Keratin associated protein 1-3" Q8IUG1 17 41033884-41034874 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 322 "skin 1: 95.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 95.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 KRTAP2-1 KAP2.1A ENSG00000212725 "Keratin associated protein 2-1" Q9BYU5 17 41046541-41047316 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 399 "skin 1: 68.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA059203 Supported NA NA "Cluster 61: Skin - Cornification" "HPA059203: AB_2683947" 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 68.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 KRTAP2-2 KAP2.2 ENSG00000214518 "Keratin associated protein 2-2" Q9BYT5 17 41054498-41055230 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 337 "skin 1: 54.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA059203 Supported NA NA "Cluster 61: Skin - Cornification" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA059203: AB_2683947" 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KRTAP2-3 KAP2.3 ENSG00000212724 "Keratin associated protein 2-3" P0C7H8 17 41059240-41060114 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 104 "skin 1: 20.6" "Cell type enhanced" "Detected in some" "Ductal cells: 104.8;Endometrial ciliated cells: 22.0;Glandular and luminal cells: 35.5;Pancreatic endocrine cells: 10.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 36.8;fHDF/TERT166: 22.2;HBF TERT88: 31.9;LHCN-M2: 41.0;U-2 OS: 15.9" HPA059203 Supported NA NA "Cluster 61: Skin - Cornification" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "HPA059203: AB_2683947" "unprognostic (2.22e-1)" "unprognostic (2.58e-2)" "unprognostic (3.79e-3)" "unprognostic (3.25e-3)" "unprognostic (2.78e-2)" "unprognostic (6.91e-2)" "unprognostic (1.38e-1)" "unprognostic (6.41e-4)" "unprognostic (7.83e-6)" "unprognostic (1.71e-1)" "unprognostic (9.36e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 20.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.1 0.0 36.8 1.2 9.0 7.6 0.4 0.3 0.0 0.0 22.2 2.2 0.1 0.0 0.6 31.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.3 0.5 0.6 0.0 0.0 0.0 0.0 41.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.2 0.0 5.4 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 15.9 1.0 1.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.1 0.0 0.0 1.5 0.3 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.1 0.0 104.8 0.0 22.0 1.6 0.4 0.0 0.0 0.0 0.6 0.4 0.0 0.0 35.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 KRTAP2-4 KAP2.4 ENSG00000213417 "Keratin associated protein 2-4" Q9BYR9 17 41065116-41065879 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 437 "skin 1: 43.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA059203 Supported NA NA "Cluster 61: Skin - Cornification" "HPA059203: AB_2683947" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KRTAP3-1 KAP3.1 ENSG00000212901 "Keratin associated protein 3-1" Q9BYR8 17 41008521-41019324 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 327 "skin 1: 231.0" "Cell type enriched" "Detected in some" 4 "Basal prostatic cells: 581.4" "Cancer enhanced" "Detected in some" "stomach cancer: 2.8;urothelial cancer: 2.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 2.0;BJ: 4.9;CACO-2: 12.7;HaCaT: 2.4;T-47d: 2.0" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" "Cluster 39: CACO-2 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "unprognostic (4.24e-1)" "unprognostic (3.00e-2)" "unprognostic (7.37e-2)" 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 231.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 12.7 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 581.4 0.0 4.0 0.0 0.9 0.0 0.0 0.0 3.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 3.1 0.3 1.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 2.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 139.6 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 1.3 0.0 1.4 11.2 0.0 0.0 71.8 KRTAP3-2 KAP3.2 ENSG00000212900 "Keratin associated protein 3-2" Q9BYR7 17 40999193-40999906 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "skin 1: 107.6" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 2.2;Squamous epithelial cells: 4.8;Suprabasal keratinocytes: 1.1;Urothelial cells: 2.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA042992 Approved NA NA "Cluster 61: Skin - Cornification" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA042992: AB_2678258" 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 107.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.2 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 1.1 0.0 0.0 0.0 0.0 2.6 KRTAP4-1 "KAP4.1, KAP4.10, KRTAP4-10" ENSG00000198443 "Keratin associated protein 4-1" Q9BYQ7 17 41184102-41185342 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 68 "skin 1: 26.6" "Cell type enhanced" "Detected in single" "Enteroendocrine cells: 1.8" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 1.1;A549: 1.7;CAPAN-2: 1.2;HDLM-2: 4.9;SCLC-21H: 1.2;SK-BR-3: 1.0" NA NA "Cluster 61: Skin - Cornification" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (1.21e-1)" "unprognostic (3.57e-1)" "unprognostic (1.64e-2)" "unprognostic (2.78e-2)" "unprognostic (1.04e-1)" "unprognostic (2.49e-2)" "unprognostic (2.42e-2)" "unprognostic (1.06e-1)" 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 26.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.7 0.0 0.0 1.2 0.0 0.0 1.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 KRTAP4-11 "KAP4.11, KAP4.14, KRTAP4-14" ENSG00000212721 "Keratin associated protein 4-11" Q9BYQ6 17 41117181-41118373 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 96 "skin 1: 9.6" "Cell type enhanced" "Detected in single" "B-cells: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KRTAP4-12 KAP4.12 ENSG00000213416 "Keratin associated protein 4-12" Q9BQ66 17 41123091-41124182 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 269 "skin 1: 26.8" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 2.3;Urothelial cells: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.0" "Lineage enhanced" "Detected in single" "B-cells: 1.0" "Not detected" "Not detected" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 61: Skin - Cornification" "Cluster 22: Epithelial cell types - Mixed function" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 KRTAP4-2 KAP4.2 ENSG00000244537 "Keratin associated protein 4-2" Q9BYR5 17 41177446-41178221 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 228 "skin 1: 22.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KRTAP4-3 KAP4.3 ENSG00000196156 "Keratin associated protein 4-3" Q9BYR4 17 41167231-41168221 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 179 "skin 1: 17.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 12 "HDLM-2: 1.1" "Not detected" "Not detected" NA NA 1400000 "Cluster 61: Skin - Cornification" "Cluster 44: HDLM-2 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 KRTAP4-4 "KAP4.13, KAP4.4, KRTAP4-13" ENSG00000171396 "Keratin associated protein 4-4" Q9BYR3 17 41159649-41160748 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 188 "skin 1: 18.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 1500000 "Cluster 61: Skin - Cornification" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KRTAP4-5 KAP4.5 ENSG00000198271 "Keratin associated protein 4-5" Q9BYR2 17 41148924-41149825 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 124 "skin 1: 12.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 KRTAP4-6 "KAP4.15, KAP4.6, KRTAP4-15" ENSG00000198090 "Keratin associated protein 4-6" Q9BYQ5 17 41139433-41140487 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 341 "skin 1: 34.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 15000000 "Cluster 61: Skin - Cornification" "Cluster 44: Endometrium - Transcription" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KRTAP4-7 KAP4.7 ENSG00000240871 "Keratin associated protein 4-7" Q9BYR0 17 41084150-41085141 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 580 "skin 1: 58.0" "Cell type enhanced" "Detected in single" "Endometrial ciliated cells: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" "Cluster 44: Endometrium - Transcription" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 58.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KRTAP4-8 KAP4.8 ENSG00000204880 "Keratin associated protein 4-8" Q9BYQ9 17 41096981-41098142 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 247 "skin 1: 24.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 6900000 "Cluster 61: Skin - Cornification" "Cluster 44: Endometrium - Transcription" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KRTAP4-9 KAP4.9 ENSG00000212722 "Keratin associated protein 4-9" Q9BYQ8 17 41105332-41106488 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 488 "skin 1: 48.8" "Cell type enhanced" "Detected in single" "Glandular and luminal cells: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" "Cluster 44: Endometrium - Transcription" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 48.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 KRTAP9-2 KAP9.2 ENSG00000239886 "Keratin associated protein 9-2" Q9BYQ4 17 41226648-41227652 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 225 "skin 1: 32.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KRTAP9-3 KAP9.3 ENSG00000204873 "Keratin associated protein 9-3" Q9BYQ3 17 41232449-41233454 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 494 "skin 1: 49.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 49.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KRTAP9-4 KAP9.4 ENSG00000241595 "Keratin associated protein 9-4" Q9BYQ2 17 41249687-41250653 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 400 "skin 1: 39.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 KRTAP9-6 "KAP9.6, KRTAP9L2" ENSG00000212659 "Keratin associated protein 9-6" A8MVA2 17 41265339-41266641 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 26 "skin 1: 2.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 KRTAP9-7 "KAP9.7, KRTAP9L1" ENSG00000180386 "Keratin associated protein 9-7" A8MTY7 17 41275659-41276697 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 81 "skin 1: 8.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 2900000 "Cluster 61: Skin - Cornification" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KRTAP9-8 KAP9.8 ENSG00000187272 "Keratin associated protein 9-8" Q9BYQ0 17 41237999-41239004 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 383 "skin 1: 38.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 31 "HDLM-2: 3.1" NA NA "Cluster 61: Skin - Cornification" "Cluster 44: HDLM-2 - Immune response" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KRTAP9-9 "KAP9.5, KAP9.9, KRTAP9-5" ENSG00000198083 "Keratin associated protein 9-9" Q9BYP9 17 41255384-41256364 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 248 "skin 1: 24.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LAD1 ENSG00000159166 "Ladinin 1" O00515 1 201380833-201399915 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 362.1;skin 1: 215.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 174.7;Ductal cells: 178.0;monocytes: 248.6;Pancreatic endocrine cells: 227.0;Proximal enterocytes: 214.7;Squamous epithelial cells: 265.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 159.9;CAPAN-2: 158.5;HaCaT: 220.4;HBEC3-KT: 190.3;hTCEpi: 181.5;MCF7: 218.3;OE19: 246.5;RT4: 164.7;SK-BR-3: 250.6" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA007256, HPA028732" Enhanced Enhanced "Actin filaments" "Secreted to extracellular matrix" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Actin filaments" "HPA007256: AB_1852681, HPA028732: AB_10602916" "unprognostic (4.95e-2)" "unprognostic (2.05e-1)" "unprognostic (3.82e-1)" "unprognostic (7.55e-3)" "unprognostic (4.66e-2)" "unprognostic (7.41e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (6.73e-4)" "unprognostic (1.06e-1)" "unprognostic (1.50e-1)" "unprognostic (1.71e-2)" "unprognostic (9.11e-2)" "unprognostic (2.31e-2)" "unprognostic (3.71e-2)" "unprognostic (1.18e-1)" "unprognostic (6.40e-2)" "unprognostic (3.28e-1)" 0.5 0.1 0.0 15.9 0.1 0.1 15.8 0.0 0.2 65.4 0.0 67.6 75.6 5.0 11.0 362.1 14.7 50.2 8.4 0.2 0.6 38.6 21.6 10.6 2.9 0.0 0.0 0.4 50.7 2.4 0.7 4.1 0.0 15.7 51.0 0.0 51.9 22.6 5.1 215.4 74.5 2.9 0.0 1.4 66.9 0.3 0.0 6.2 3.5 0.2 47.7 71.4 135.2 0.0 159.9 1.3 0.0 0.3 0.0 0.0 57.0 0.0 0.0 0.1 0.1 127.3 158.5 0.0 8.9 0.0 0.0 220.4 0.0 190.3 0.1 0.2 0.0 0.0 0.1 79.3 0.0 0.1 0.2 0.1 181.5 0.1 36.8 0.0 0.1 0.0 0.1 0.7 0.1 218.3 0.2 0.4 3.7 246.5 2.6 0.2 7.4 2.3 126.0 164.7 9.1 0.2 0.1 250.6 3.1 5.4 37.6 0.4 0.0 0.1 0.5 0.5 0.6 0.1 0.4 0.2 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.2 35.4 0.0 0.9 88.5 112.1 47.2 46.7 0.0 15.4 14.1 2.1 110.1 31.3 31.3 0.0 3.8 0.5 174.7 45.0 178.0 1.1 26.2 2.6 1.6 18.1 0.0 0.0 121.9 5.9 2.6 85.1 34.5 0.0 0.0 0.4 9.0 0.5 0.0 0.0 53.8 18.3 0.6 16.0 3.6 0.0 2.6 10.6 0.0 248.6 0.0 0.0 0.0 0.0 227.0 109.6 0.4 2.9 77.1 214.7 71.8 4.8 0.0 0.0 0.0 3.2 0.0 0.3 265.6 152.7 10.4 1.5 0.0 136.2 150.2 LCK ENSG00000182866 "LCK proto-oncogene, Src family tyrosine kinase" P06239 1 32251239-32286165 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Host-virus interaction" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 15 "lymphoid tissue: 343.0" "Group enriched" "Detected in many" 9 "dendritic cells: 143.9;NK-cells: 272.9;T-cells: 255.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in all" 12 "gdT-cell: 1109.8;MAIT T-cell: 1034.8;memory CD4 T-cell: 1123.8;memory CD8 T-cell: 1201.7;naive CD4 T-cell: 1260.7;naive CD8 T-cell: 1168.7;NK-cell: 641.5;T-reg: 1682.7" "Group enriched" "Detected in all" 12 "NK-cells: 641.5;T-cells: 1682.7" "Group enriched" "Detected in some" 6 "JURKAT: 365.7;MOLT-4: 536.9;U-698: 302.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in single" "HPA003494, CAB003816" Enhanced Approved "Golgi apparatus" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Golgi apparatus" "CAB003816: AB_562158, HPA003494: AB_1852751" "unprognostic (6.38e-3)" "unprognostic (5.45e-3)" "unprognostic (8.39e-2)" "prognostic favorable (2.96e-6)" "unprognostic (2.20e-2)" "prognostic favorable (2.91e-4)" "unprognostic (4.78e-3)" "unprognostic (1.33e-2)" "prognostic favorable (5.65e-5)" "unprognostic (3.07e-2)" "unprognostic (3.80e-2)" "unprognostic (2.83e-1)" "prognostic unfavorable (2.60e-5)" "unprognostic (8.15e-2)" "unprognostic (4.05e-2)" "unprognostic (7.39e-2)" "unprognostic (1.17e-2)" 3.4 2.2 0.4 50.6 0.5 13.7 2.3 0.4 0.5 2.2 0.7 6.9 7.6 1.7 13.0 3.9 2.1 9.4 1.9 0.5 0.4 3.8 3.8 11.4 111.0 0.8 0.5 1.6 0.9 0.5 0.8 1.1 0.6 2.8 6.5 0.0 4.8 1.4 1.3 1.9 23.1 2.3 0.6 39.9 12.1 1.1 0.5 343.0 3.7 1.4 79.6 13.2 2.7 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.7 64.1 3.5 0.0 0.3 0.1 0.0 0.2 0.0 0.1 0.6 0.0 0.0 1.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 365.7 0.2 0.0 0.0 0.0 536.9 0.2 5.9 4.6 0.3 20.6 0.1 0.3 0.3 0.2 0.1 0.0 0.1 0.3 0.3 0.4 0.6 0.4 0.0 0.0 1.7 0.1 0.1 0.7 0.3 302.7 0.0 0.1 0.0 12.8 5.2 6.0 1109.8 4.9 1034.8 62.0 1123.8 1201.7 5.2 98.9 1260.7 1168.7 33.6 641.5 6.0 7.7 1682.7 1836.9 0.4 0.5 0.4 0.5 0.5 0.4 0.8 0.5 0.6 0.6 0.5 0.6 4.9 0.0 9.3 0.0 23.4 4.6 1.2 0.4 0.0 0.0 3.5 5.2 1.8 4.3 1.6 3.7 0.0 0.3 143.9 0.9 0.0 0.6 0.1 1.0 0.5 3.4 2.4 10.1 0.2 0.5 0.2 3.1 7.7 0.7 5.1 0.0 4.6 1.5 0.3 0.0 0.2 0.3 0.0 7.8 7.3 0.0 0.0 8.1 3.6 0.0 8.7 0.0 272.9 0.5 0.1 4.7 0.0 0.4 15.7 1.0 0.0 1.4 1.8 0.0 0.0 1.5 2.4 4.5 2.0 0.5 3.1 0.4 255.5 2.9 1.3 1.1 LEO1 ENSG00000166477 "LEO1 homolog, Paf1/RNA polymerase II complex component" Q8WVC0 15 51938025-51971778 "Predicted intracellular proteins" "Transcription, Transcription regulation, Wnt signaling pathway" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 7 "granulocytes: 272.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040741, HPA040941" Enhanced Enhanced "Nucleoplasm,Nucleoli fibrillar center,Centrosome" No No "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "Nucleoplasm, Nucleoli fibrillar center" Centrosome "HPA040741: AB_10794859, HPA040941: AB_10805832" "unprognostic (2.76e-2)" "unprognostic (2.14e-2)" "unprognostic (2.44e-1)" "unprognostic (1.81e-3)" "unprognostic (2.85e-2)" "unprognostic (1.03e-1)" "unprognostic (1.09e-2)" "unprognostic (1.04e-2)" "unprognostic (1.83e-2)" "unprognostic (2.10e-1)" "unprognostic (1.20e-1)" "unprognostic (1.02e-2)" "unprognostic (1.30e-1)" "unprognostic (1.04e-1)" "unprognostic (8.48e-2)" "unprognostic (2.10e-2)" "unprognostic (1.08e-1)" 10.2 11.4 8.1 13.8 8.8 9.0 15.5 14.7 12.9 11.6 6.4 17.0 13.3 10.4 10.0 19.8 8.7 13.2 8.1 8.0 10.0 13.7 22.2 9.7 18.0 8.0 8.1 8.5 8.1 18.8 9.1 12.1 7.7 12.3 19.2 12.0 18.5 8.6 13.9 20.8 14.5 11.7 6.9 10.5 13.2 9.3 8.3 22.1 11.1 11.7 17.9 19.3 14.0 10.0 28.0 63.9 40.3 32.6 40.7 35.0 28.8 44.4 36.6 37.3 33.9 44.3 17.9 56.2 25.3 45.8 41.3 53.2 54.2 39.6 35.8 37.5 24.5 88.5 50.6 78.5 32.0 80.7 118.2 37.9 30.5 29.2 37.6 35.2 37.0 46.5 54.6 30.1 44.9 118.7 43.0 61.1 17.4 82.6 27.0 47.6 69.7 58.9 32.8 77.0 28.5 43.4 33.9 51.5 36.5 43.8 42.8 72.6 44.4 36.8 25.5 34.3 53.7 23.4 78.2 50.7 32.2 113.1 40.0 11.5 14.5 15.7 27.4 23.3 25.7 18.7 27.2 22.3 23.8 16.4 27.9 25.2 3.3 30.9 26.0 17.8 31.7 16.3 8.1 8.8 14.7 12.9 8.0 10.0 8.0 8.1 7.7 6.9 8.3 10.0 16.2 35.3 24.6 10.1 15.2 26.1 16.8 33.4 18.2 38.2 11.8 10.2 21.2 17.2 37.0 7.3 10.4 24.9 24.8 24.6 15.6 26.3 2.4 19.5 38.8 18.0 7.7 12.4 16.5 24.2 26.7 19.9 15.8 29.8 272.8 16.2 10.0 18.0 19.5 26.9 16.9 17.9 26.4 14.8 6.0 2.7 8.1 13.0 3.6 5.6 12.8 23.1 22.6 13.0 13.3 18.2 14.7 13.5 11.0 9.0 20.5 23.3 31.4 23.2 6.6 18.5 29.3 21.5 11.0 19.5 24.7 17.6 25.0 23.8 17.0 21.2 LEXM "C1orf177, FLJ40201, LEM" ENSG00000162398 "Lymphocyte expansion molecule" Q3ZCV2 1 54806063-54842252 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "esophagus: 12.7;testis: 4.8;vagina: 4.0" "Group enriched" "Detected in some" 5 "Early spermatids: 37.7;Late spermatids: 46.0" "Low cancer specificity" "Detected in single" "Region enhanced" "Detected in single" "basal ganglia: 1.6" "Immune cell enhanced" "Detected in some" "gdT-cell: 3.8" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA035889, HPA035890" Uncertain NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 34: Spermatids - Unknown function" "HPA035889: AB_2674844, HPA035890: AB_10669535" "unprognostic (1.61e-1)" "unprognostic (2.18e-2)" "unprognostic (5.01e-2)" "unprognostic (3.69e-2)" "unprognostic (1.50e-2)" "unprognostic (8.32e-2)" "unprognostic (7.28e-2)" "unprognostic (1.81e-1)" "unprognostic (1.41e-1)" "unprognostic (5.13e-3)" "unprognostic (1.29e-1)" "unprognostic (1.03e-4)" "unprognostic (2.11e-1)" "unprognostic (1.38e-1)" "unprognostic (3.64e-1)" "unprognostic (1.81e-1)" 0.0 0.1 0.1 0.0 1.6 0.1 0.1 0.1 0.9 1.5 0.0 0.4 1.6 0.0 0.1 12.7 0.1 0.0 0.0 0.1 0.2 0.1 0.4 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.4 0.0 0.7 0.0 0.0 1.0 1.3 0.0 0.0 0.1 0.2 4.8 0.1 0.0 0.0 0.0 0.5 0.0 4.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.9 3.8 0.0 0.2 0.0 0.8 2.0 0.0 0.0 0.1 2.5 0.0 2.0 0.0 0.1 0.2 1.0 0.1 1.6 0.1 0.9 0.1 0.2 0.3 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.6 0.0 0.0 37.7 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.5 0.0 0.0 0.0 46.0 0.3 0.0 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.1 0.0 0.7 0.3 0.0 4.1 0.3 0.0 0.0 0.0 0.0 0.0 1.4 0.6 0.6 0.0 0.0 1.0 0.0 0.6 0.2 LGALS12 GRIP1 ENSG00000133317 "Galectin 12" Q96DT0 11 63506052-63516774 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 78.3;breast: 41.3" "Cell type enhanced" "Detected in some" "granulocytes: 17.8;Macrophages: 13.3;monocytes: 2.5;Muller glia cells: 3.9" "Cancer enhanced" "Detected in some" "renal cancer: 1.6" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 20 "eosinophil: 554.9" "Lineage enriched" "Detected in many" 20 "granulocytes: 554.9" "Group enriched" "Detected in some" 14 "ASC diff: 28.9;HL-60: 53.0;NB-4: 109.4;U-937: 112.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA021124 Approved Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 24: NB-4 - Immune response" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "HPA021124: " "unprognostic (3.89e-2)" "unprognostic (4.40e-2)" "unprognostic (5.17e-2)" "unprognostic (1.79e-1)" "unprognostic (6.26e-2)" "unprognostic (4.75e-2)" "unprognostic (1.51e-1)" "unprognostic (4.31e-2)" "unprognostic (1.01e-1)" "unprognostic (2.13e-3)" "unprognostic (4.69e-2)" "unprognostic (3.08e-1)" "prognostic unfavorable (4.60e-7)" "unprognostic (2.72e-3)" "unprognostic (1.19e-1)" "unprognostic (6.22e-2)" "unprognostic (8.60e-2)" 78.3 0.8 0.1 2.7 0.2 18.4 41.3 0.1 0.2 0.1 0.4 0.9 0.5 0.2 0.0 0.2 1.0 1.7 2.1 0.1 0.2 0.3 0.3 1.0 0.1 0.2 0.2 0.2 0.6 0.0 0.0 0.1 0.2 0.4 0.6 1.9 4.5 0.7 0.5 1.0 2.0 1.0 0.2 1.1 0.9 0.0 0.1 0.3 0.7 1.4 0.0 1.0 0.3 0.2 0.0 0.0 0.0 0.0 28.9 0.1 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.8 53.0 3.3 3.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 109.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 5.3 0.0 0.0 0.0 0.0 0.0 2.4 0.2 0.0 0.0 112.2 0.0 15.5 28.1 554.9 0.2 3.3 0.2 0.0 0.0 0.0 7.5 0.1 0.1 0.1 5.7 0.2 0.5 0.7 0.3 17.3 0.1 0.2 0.1 0.2 0.1 0.2 0.2 0.2 0.2 0.2 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 17.8 0.0 1.1 0.1 1.5 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 13.3 0.0 0.0 2.5 3.9 0.0 0.5 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 LHX2 "hLhx2, LH-2" ENSG00000106689 "LIM homeobox 2" P50458 9 124001670-124033301 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 99.8;choroid plexus: 48.5;retina: 34.1" "Cell type enhanced" "Detected in some" "Astrocytes: 68.6;Early spermatids: 43.1;Muller glia cells: 254.6" "Group enriched" "Detected in many" 5 "cervical cancer: 3.2;glioma: 10.7;melanoma: 3.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 23.2;GAMG: 17.9;HAP1: 23.5;HeLa: 15.5;NTERA-2: 28.5;U-138 MG: 14.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA000838 Supported Approved Nucleoplasm NA NA "Cluster 65: Brain - Ion transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 5: Muller glia cells - Visual perception" Nucleoplasm "HPA000838: AB_2666109" "unprognostic (3.60e-3)" "prognostic favorable (9.52e-4)" "unprognostic (3.52e-1)" "unprognostic (9.97e-2)" "unprognostic (1.29e-1)" "unprognostic (1.12e-2)" "unprognostic (6.37e-3)" "unprognostic (1.07e-1)" "unprognostic (4.59e-2)" "unprognostic (3.24e-1)" "unprognostic (2.96e-1)" "unprognostic (1.32e-2)" "unprognostic (4.66e-15)" "unprognostic (1.72e-1)" "unprognostic (2.92e-1)" "unprognostic (2.46e-2)" "unprognostic (1.77e-1)" 0.1 0.1 77.8 0.2 78.1 0.0 0.2 48.5 99.8 0.0 48.5 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 88.1 51.2 0.3 6.7 0.0 0.3 49.5 52.7 0.2 0.0 0.0 9.8 3.4 50.2 0.0 0.1 34.1 0.1 0.0 0.0 6.1 0.2 0.0 48.3 0.1 0.0 3.0 54.9 0.1 0.0 0.0 0.2 0.1 0.0 73.9 0.0 7.2 0.2 23.2 0.0 0.3 2.6 0.7 0.3 1.8 0.2 7.8 0.0 0.2 3.0 1.4 17.9 0.2 23.5 0.0 0.9 0.0 5.0 0.0 15.5 0.4 1.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.7 12.1 0.0 0.2 28.5 0.0 7.0 6.5 0.1 0.0 0.0 0.1 9.2 0.1 5.7 0.0 0.0 0.2 8.0 3.1 0.0 14.6 0.6 4.2 1.1 0.4 5.0 0.0 0.8 3.4 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 77.8 78.1 48.5 99.8 88.1 51.2 49.5 52.7 50.2 48.3 54.9 73.9 0.1 0.0 0.0 68.6 0.2 0.0 0.0 0.0 0.0 3.2 0.1 0.3 0.6 0.0 0.0 0.0 2.1 0.1 0.0 0.1 0.0 0.0 43.1 0.1 0.0 0.3 0.0 0.0 20.6 0.0 8.9 0.1 0.0 0.0 0.0 0.1 3.9 0.0 4.0 8.4 2.5 0.0 0.0 0.0 0.3 21.7 0.0 0.1 0.0 1.9 0.0 254.6 0.0 5.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 0.0 0.4 0.2 4.2 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 LIPE HSL ENSG00000079435 "Lipase E, hormone sensitive type" Q05469 19 42401514-42427388 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol metabolism, Lipid degradation, Lipid metabolism, Steroid metabolism, Sterol metabolism" Hydrolase "Diabetes mellitus, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "adipose tissue: 834.5;breast: 524.7" "Cell type enhanced" "Detected in many" "Adipocytes: 76.1;Early spermatids: 127.8;Late spermatids: 236.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in many" 7 "ASC diff: 136.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006567, CAB017700" Enhanced Supported Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "CAB017700: AB_2135504, HPA006567: AB_2667618" "unprognostic (4.24e-2)" "unprognostic (2.46e-2)" "unprognostic (8.99e-3)" "unprognostic (3.74e-2)" "unprognostic (1.77e-1)" "unprognostic (3.38e-3)" "unprognostic (5.68e-2)" "unprognostic (2.84e-1)" "unprognostic (3.11e-1)" "unprognostic (9.44e-2)" "prognostic favorable (1.15e-4)" "unprognostic (1.52e-1)" "unprognostic (3.63e-10)" "unprognostic (1.47e-1)" "unprognostic (1.83e-1)" "unprognostic (3.76e-2)" "unprognostic (2.34e-3)" 834.5 45.1 22.7 7.7 71.7 5.0 524.7 77.2 41.5 5.1 0.6 10.9 5.3 6.4 1.2 8.6 5.8 3.7 32.5 23.8 42.6 7.7 1.5 3.7 7.3 100.3 73.9 4.9 6.2 4.7 6.9 2.9 90.0 7.1 1.4 2.0 17.2 2.6 19.7 23.6 24.4 2.6 44.0 14.4 8.5 68.6 57.1 6.9 9.6 23.3 3.7 14.2 7.7 116.9 12.7 9.6 6.0 2.3 136.8 1.3 0.1 5.8 3.1 9.2 8.5 2.3 4.6 20.6 6.3 1.8 4.5 5.6 3.7 11.5 1.0 4.0 6.1 5.8 5.3 0.2 2.7 0.1 13.9 1.2 10.7 1.5 2.1 1.3 2.6 8.5 2.7 12.8 1.2 0.1 14.8 0.5 0.8 9.7 2.7 12.2 1.1 6.9 2.6 13.1 8.5 8.8 5.1 5.7 5.6 0.3 1.5 7.5 4.7 2.5 7.8 1.1 5.3 9.7 8.5 15.6 6.3 0.7 8.7 11.0 8.6 3.8 2.5 4.7 2.3 3.4 3.2 3.7 3.6 4.5 2.8 2.5 1.5 3.6 2.7 2.9 3.0 3.1 22.7 71.7 77.2 41.5 23.8 42.6 100.3 73.9 90.0 44.0 57.1 116.9 76.1 0.0 3.3 4.2 8.1 4.1 12.1 2.4 4.6 11.0 4.8 2.9 2.5 0.0 2.0 1.8 10.4 0.1 4.8 1.3 1.9 8.0 127.8 0.9 3.4 10.2 0.0 5.3 4.6 2.7 0.1 2.0 3.6 1.5 0.0 6.6 17.9 0.0 0.6 8.4 6.7 2.0 6.1 2.2 2.4 236.5 3.1 0.8 5.4 4.7 0.9 4.0 6.2 6.0 37.9 1.8 0.7 1.5 3.0 6.7 18.4 1.5 0.8 13.9 0.0 7.2 2.1 39.4 13.1 2.5 2.4 0.0 5.1 5.2 2.9 10.7 LIPN "bA186O14.3, LIPL4" ENSG00000204020 "Lipase family member N" Q5VXI9 10 88759982-88779626 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" Hydrolase Ichthyosis "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 9 "skin 1: 26.7" "Group enriched" "Detected in some" 4 "Macrophages: 7.5;monocytes: 2.5" "Cancer enhanced" "Detected in single" "head and neck cancer: 0.6" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "classical monocyte: 2.9;eosinophil: 10.3;intermediate monocyte: 7.5;neutrophil: 5.4;non-classical monocyte: 8.5" "Group enriched" "Detected in many" 8 "granulocytes: 10.3;monocytes: 8.5" "Cell line enhanced" "Detected in single" "HL-60: 2.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted in other tissues" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 61: Skin - Cornification" "Cluster 32: U-937 - Innate immune response" "Cluster 41: Macrophages - Immune response" "unprognostic (2.01e-1)" "unprognostic (3.48e-1)" "unprognostic (1.13e-1)" "unprognostic (2.99e-1)" "unprognostic (1.08e-1)" "unprognostic (3.27e-1)" "unprognostic (1.07e-1)" "unprognostic (2.03e-2)" "unprognostic (9.75e-2)" "unprognostic (2.54e-2)" "unprognostic (4.40e-2)" "unprognostic (5.77e-3)" "unprognostic (1.65e-1)" 1.3 0.3 0.0 2.8 0.0 2.8 1.7 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.4 0.6 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.1 0.0 0.1 26.7 0.1 0.3 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.8 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 2.9 10.3 0.0 7.5 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 5.4 0.0 8.5 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.0 1.2 0.7 0.0 0.0 7.5 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 LMNB1 ENSG00000113368 "Lamin B1" P20700 5 126776623-126837020 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Leukodystrophy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 34.0;lymphoid tissue: 49.2" "Cell type enhanced" "Detected in many" "Early spermatids: 92.5;Erythroid cells: 67.3;Extravillous trophoblasts: 68.2;granulocytes: 93.6;Late spermatids: 72.1;monocytes: 59.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005269, HPA050524, CAB079757, CAB079954" Supported Supported "Nuclear membrane" NA NA 2100000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 32: U-937 - Innate immune response" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear membrane" "CAB005269: AB_648156, CAB079757: AB_2665863, CAB079954: , HPA050524: AB_2681156" "unprognostic (1.52e-1)" "unprognostic (2.53e-2)" "unprognostic (4.96e-3)" "unprognostic (3.70e-2)" "unprognostic (1.61e-1)" "unprognostic (8.65e-3)" "prognostic unfavorable (3.08e-6)" "unprognostic (2.06e-2)" "unprognostic (6.62e-3)" "unprognostic (5.28e-2)" "unprognostic (2.13e-3)" "unprognostic (2.33e-2)" "prognostic unfavorable (3.33e-16)" "unprognostic (1.33e-2)" "unprognostic (2.06e-1)" "unprognostic (1.08e-1)" "unprognostic (2.55e-1)" 4.2 1.6 1.9 26.6 1.8 34.0 2.9 9.8 2.1 3.7 0.5 14.9 11.2 2.8 0.5 14.2 1.8 3.4 1.5 1.6 3.3 3.5 4.9 6.0 34.8 2.9 2.3 2.2 2.4 0.7 2.0 6.7 2.4 1.6 13.0 6.4 3.4 1.6 1.0 8.6 14.2 3.5 2.1 13.3 7.9 2.2 2.3 49.2 1.6 1.4 29.2 6.8 4.8 1.8 132.7 43.4 131.6 126.6 3.3 9.3 170.6 60.6 17.8 66.1 71.3 113.4 107.2 229.4 103.2 21.4 31.5 72.4 90.9 42.1 72.2 162.9 112.1 147.5 49.1 67.2 1.4 176.6 95.6 3.0 0.9 35.2 16.0 12.8 54.9 92.0 87.1 86.3 46.6 109.7 322.8 347.5 99.0 54.1 60.0 152.6 259.4 93.1 36.6 59.6 151.4 80.3 98.4 41.7 36.6 45.2 76.2 202.0 46.9 48.7 132.0 36.6 131.3 56.8 46.4 197.3 25.0 247.1 73.8 1.4 14.4 4.8 2.1 5.6 1.6 4.2 4.3 2.8 15.3 2.9 3.1 2.8 9.3 2.4 1.5 4.6 12.4 6.4 1.9 1.8 9.8 2.1 1.6 3.3 2.9 2.3 2.4 2.1 2.3 1.8 3.4 0.0 4.3 0.3 20.1 5.0 1.9 2.0 8.0 6.4 4.3 5.1 1.6 4.3 3.3 0.0 8.4 39.4 56.0 7.7 1.9 1.8 92.5 3.9 4.8 8.8 6.1 67.3 6.8 0.8 68.2 8.1 11.7 7.6 93.6 23.9 3.6 3.1 21.8 5.0 9.1 19.3 0.0 13.1 17.9 72.1 2.1 27.9 1.8 1.9 59.5 3.8 13.4 5.5 1.1 1.1 8.4 0.4 50.6 1.1 3.8 2.1 1.9 17.5 0.0 2.5 7.3 3.4 8.9 27.3 5.4 4.7 34.2 3.0 35.8 1.4 LMX1B NPS1 ENSG00000136944 "LIM homeobox transcription factor 1 beta" O60663 9 126613928-126701032 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.2;salivary gland: 18.5" "Cell type enhanced" "Detected in some" "Breast glandular cells: 8.3;Breast myoepithelial cells: 7.2;Cardiomyocytes: 1.9;Early spermatids: 1.6;Spermatogonia: 2.1" "Cancer enriched" "Detected in some" 14 "breast cancer: 12.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 3.5;HEK 293: 3.6;MCF7: 11.9;OE19: 10.4;T-47d: 8.1" "Region enhanced" "Detected in some" "pons and medulla: 2.3" "Region enhanced" "Detected in many" "midbrain: 5.0" "HPA073716, HPA075656" Approved Nucleoplasm NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 35: Glandular cells - Unknown function" Nucleoplasm "HPA073716: AB_2686630, HPA075656: " "unprognostic (4.17e-1)" "unprognostic (4.72e-2)" "unprognostic (2.81e-2)" "unprognostic (2.53e-4)" "unprognostic (1.73e-1)" "unprognostic (1.50e-4)" "unprognostic (1.86e-1)" "unprognostic (2.20e-2)" "unprognostic (3.41e-1)" "unprognostic (2.26e-1)" "unprognostic (1.34e-2)" "unprognostic (3.51e-3)" "unprognostic (1.63e-5)" "unprognostic (1.69e-1)" "unprognostic (1.23e-1)" "unprognostic (1.56e-6)" "unprognostic (1.13e-2)" 0.6 0.0 0.1 0.0 0.1 0.1 4.1 0.1 5.6 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 2.0 1.0 1.0 3.6 0.0 0.1 0.0 3.8 9.2 0.0 0.2 1.1 0.2 0.0 3.3 0.0 0.0 0.0 18.5 0.0 0.1 2.1 0.1 0.0 6.8 0.0 0.1 1.4 2.6 0.0 0.4 0.0 0.0 0.0 0.0 0.5 1.2 0.6 0.3 2.7 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.9 0.6 0.0 0.3 0.0 2.5 0.6 3.5 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.5 0.0 1.8 0.0 0.0 0.1 0.0 0.0 0.0 11.9 0.0 0.0 0.0 10.4 0.0 0.0 2.4 0.0 0.0 0.1 0.0 1.1 0.3 0.0 0.2 0.1 8.1 0.1 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 5.6 1.0 1.0 3.8 9.2 3.3 6.8 2.6 0.5 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 8.3 7.2 1.9 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.8 1.6 0.2 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.1 2.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 LRP4 "CLSS, LRP-4, MEGF7, SOST2" ENSG00000134569 "LDL receptor related protein 4" O75096 11 46856717-46918642 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Differentiation, Endocytosis, Wnt signaling pathway" "Developmental protein, Receptor" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 46.7;skin 1: 31.6" "Cell type enhanced" "Detected in many" "Astrocytes: 123.1;Cone photoreceptor cells: 41.7;Distal enterocytes: 31.1;Oligodendrocyte precursor cells: 137.2;Oligodendrocytes: 31.3" "Group enriched" "Detected in all" 4 "colorectal cancer: 12.2;endometrial cancer: 8.6;glioma: 13.2;testis cancer: 15.6;thyroid cancer: 28.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 21.3;SuSa: 16.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011934, HPA012300" Approved Uncertain Nucleoplasm,Nucleoli,Mitochondria NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" "Nucleoplasm, Nucleoli, Mitochondria" "HPA011934: AB_1853286, HPA012300: AB_1853288" "unprognostic (1.46e-1)" "unprognostic (4.07e-2)" "unprognostic (2.86e-1)" "unprognostic (1.33e-2)" "unprognostic (4.39e-2)" "unprognostic (9.73e-3)" "unprognostic (5.29e-4)" "unprognostic (8.61e-2)" "unprognostic (2.29e-2)" "unprognostic (2.77e-1)" "unprognostic (1.92e-1)" "unprognostic (1.33e-1)" "unprognostic (7.59e-2)" "unprognostic (7.95e-2)" "unprognostic (2.76e-2)" "unprognostic (9.90e-3)" "unprognostic (6.79e-2)" 0.7 1.4 23.3 0.9 30.5 0.0 1.5 19.1 21.3 2.3 0.0 4.8 3.4 1.6 0.9 1.8 1.4 2.0 6.9 24.2 16.0 0.7 0.2 2.9 0.1 46.7 23.0 4.6 2.2 5.6 2.6 2.6 19.8 2.1 3.4 7.9 1.7 2.3 4.4 31.6 4.9 1.5 21.3 3.9 7.8 1.1 30.9 1.5 2.4 7.7 0.3 0.9 1.4 25.6 0.1 9.6 21.3 6.5 13.4 3.7 4.9 1.0 1.9 2.8 3.2 2.8 0.0 0.0 1.4 11.4 3.1 3.9 12.0 7.5 2.2 0.0 10.3 1.0 3.8 6.8 2.8 0.1 1.9 4.5 4.2 4.4 1.1 2.5 2.5 2.6 0.9 0.0 1.6 0.8 0.2 0.3 11.9 0.0 0.9 1.6 7.3 0.0 0.3 2.8 0.1 14.2 1.2 0.0 3.4 16.2 0.3 0.5 0.2 5.7 3.5 6.5 2.1 0.0 0.0 0.4 4.3 0.7 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.3 30.5 19.1 21.3 24.2 16.0 46.7 23.0 19.8 21.3 30.9 25.6 0.2 0.0 1.9 123.1 0.0 8.2 2.7 2.4 10.8 0.5 0.3 1.9 6.2 0.0 1.9 1.8 41.7 2.6 0.0 31.1 1.9 0.0 0.5 1.0 4.7 1.0 0.0 0.0 19.7 0.4 0.4 5.0 3.1 4.4 5.1 1.6 1.8 0.4 0.2 0.0 18.6 2.8 0.0 0.0 0.4 0.0 1.8 0.2 1.8 15.0 0.6 9.3 0.0 137.2 31.3 0.3 3.0 1.2 0.0 1.0 8.0 0.3 1.1 2.7 0.0 12.4 0.9 0.2 0.8 2.3 10.9 1.4 0.2 8.4 3.3 0.8 LRRC18 "MGC34773, UNQ933, UNQ9338, VKGE9338" ENSG00000165383 "Leucine rich repeat containing 18" Q8N456 10 48909483-48914232 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "choroid plexus: 12.1;fallopian tube: 7.6;testis: 14.0" "Group enriched" "Detected in some" 8 "Early spermatids: 222.0;Late spermatids: 64.1" "Cancer enhanced" "Detected in single" "endometrial cancer: 1.0" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA039256, HPA076699" Enhanced Approved Cytosol NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 29: Early spermatids - Spermatogenesis" Cytosol "HPA039256: AB_10671873, HPA076699: " "unprognostic (1.31e-2)" "unprognostic (3.66e-2)" "unprognostic (9.83e-4)" "unprognostic (3.10e-1)" "unprognostic (4.82e-2)" "unprognostic (1.98e-1)" "unprognostic (2.00e-1)" "unprognostic (8.11e-2)" "unprognostic (1.11e-1)" "unprognostic (3.16e-2)" "unprognostic (8.57e-3)" "unprognostic (4.08e-1)" "unprognostic (1.13e-1)" 0.0 0.0 0.3 0.4 0.2 0.4 0.3 0.5 0.3 0.6 12.1 0.4 0.2 0.2 0.0 0.1 7.6 0.3 0.3 0.8 0.3 0.0 0.0 1.5 0.2 1.0 0.9 0.1 0.0 0.0 0.0 0.0 0.8 0.2 0.7 0.0 0.1 0.0 0.0 0.8 0.4 0.2 0.6 0.1 0.2 14.0 0.6 0.0 0.0 0.0 0.1 0.3 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.5 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.5 0.3 0.8 0.3 1.0 0.9 0.8 0.6 0.6 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 222.0 6.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.3 64.1 1.8 0.1 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 17.8 0.0 0.0 0.0 0.2 2.8 0.6 0.0 0.1 0.0 0.0 0.2 0.0 0.0 LRRC26 bA350O14.10 ENSG00000184709 "Leucine rich repeat containing 26" Q2I0M4 9 137168758-137170051 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "salivary gland: 290.0" "Cell type enriched" "Detected in many" 5 "Intestinal goblet cells: 598.0" "Cancer enriched" "Detected in many" 5 "prostate cancer: 47.6" "Region enriched" "Detected in single" 5 "cerebellum: 2.6" "Immune cell enriched" "Detected in single" 1177 "plasmacytoid DC: 117.6" "Lineage enriched" "Detected in single" 1177 "dendritic cells: 117.6" "Cell line enriched" "Detected in some" 6 "RPMI-8226: 130.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA056312 Approved Supported "Nucleoli fibrillar center,Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 25: RPMI-8226 - Immune response" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane" "Nucleoli fibrillar center" "HPA056312: AB_2683098" "unprognostic (1.75e-1)" "unprognostic (2.28e-2)" "unprognostic (1.04e-2)" "prognostic favorable (4.82e-6)" "unprognostic (3.39e-1)" "unprognostic (1.67e-2)" "unprognostic (1.82e-1)" "unprognostic (2.13e-2)" "unprognostic (1.98e-1)" "unprognostic (1.06e-1)" "unprognostic (1.75e-1)" "prognostic favorable (3.48e-4)" "unprognostic (3.27e-1)" "unprognostic (2.29e-1)" 0.1 0.0 0.2 0.3 0.4 0.0 7.3 2.6 0.5 0.4 0.0 11.2 1.7 1.1 0.0 2.8 1.1 0.0 0.0 0.1 0.5 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.6 0.0 0.1 0.0 0.1 53.1 0.5 0.0 290.0 0.5 0.0 5.1 7.2 0.0 0.2 0.1 5.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.4 0.0 0.0 0.0 5.4 0.7 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.9 0.1 0.3 0.7 20.8 0.1 130.9 0.0 0.0 1.0 0.2 0.5 6.0 0.0 0.0 2.7 0.5 0.1 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 117.6 0.0 0.5 0.2 0.4 2.6 0.5 0.1 0.5 0.0 0.1 0.1 0.2 0.0 0.0 0.6 0.0 0.0 0.3 1.2 1.0 1.7 0.5 0.0 0.0 101.2 64.4 0.4 4.3 1.0 0.0 0.0 0.1 81.8 15.2 1.9 0.1 0.5 13.0 1.6 1.0 9.0 0.0 0.1 0.4 0.0 0.4 9.2 21.3 0.0 0.0 0.0 0.0 0.1 0.0 0.3 598.0 4.1 0.0 0.9 1.1 0.0 1.4 56.9 0.0 0.6 0.0 0.0 0.0 0.1 0.2 11.8 0.0 0.6 28.4 28.8 0.1 0.4 0.0 0.0 0.0 0.4 0.2 2.8 3.5 0.3 0.0 0.6 0.0 24.3 3.7 LRRC37B ENSG00000185158 "Leucine rich repeat containing 37B" Q96QE4 17 32007872-32053504 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 25.1" "Cell type enhanced" "Detected in many" "Early spermatids: 101.9;Excitatory neurons: 45.4;Spermatocytes: 66.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 3.8" "Group enriched" "Detected in many" 4 "granulocytes: 1.5;NK-cells: 3.8;T-cells: 2.6" "Low cell line specificity" "Detected in all" HPA015135 Approved Approved Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 24: NB-4 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "HPA015135: AB_1853309" "unprognostic (5.46e-3)" "unprognostic (2.56e-2)" "unprognostic (5.08e-2)" "unprognostic (5.30e-2)" "unprognostic (2.39e-1)" "unprognostic (1.04e-1)" "unprognostic (3.60e-2)" "unprognostic (9.65e-3)" "unprognostic (5.06e-2)" "unprognostic (3.19e-2)" "unprognostic (1.72e-4)" "unprognostic (6.99e-2)" "unprognostic (5.72e-3)" "unprognostic (6.94e-2)" "unprognostic (3.35e-2)" "unprognostic (4.97e-2)" "unprognostic (1.36e-3)" 4.7 3.7 7.5 3.7 6.6 25.1 5.2 13.7 10.3 6.9 0.9 4.9 3.4 6.2 4.7 4.2 6.8 3.6 2.6 8.0 4.2 3.6 2.1 5.6 4.6 4.8 3.4 9.1 3.2 5.7 8.3 3.5 5.2 4.7 4.6 6.9 4.7 2.8 3.5 10.5 5.0 5.2 2.2 6.2 5.0 17.9 5.1 10.9 4.1 1.4 4.5 4.6 5.9 7.1 2.7 5.0 15.6 8.9 3.9 4.7 4.8 2.4 9.0 6.9 8.7 6.8 2.6 7.1 5.0 5.5 8.5 3.6 9.3 1.9 5.4 2.2 7.6 3.4 8.1 2.6 5.8 13.3 5.8 5.1 5.9 6.3 15.9 6.6 5.9 12.1 8.2 6.8 2.6 2.5 23.4 20.5 4.8 2.5 3.3 16.2 3.7 5.9 3.9 6.6 2.9 5.0 6.1 3.8 8.8 5.2 10.4 20.9 5.0 4.8 3.2 10.8 6.1 6.8 10.4 7.5 3.4 13.2 3.4 0.0 0.2 1.5 0.5 0.2 1.0 0.1 1.0 1.4 0.4 0.4 1.4 0.4 0.5 3.8 0.1 0.6 2.6 0.3 7.5 6.6 13.7 10.3 8.0 4.2 4.8 3.4 5.2 2.2 5.1 7.1 7.4 6.4 9.1 39.2 5.1 4.1 6.9 3.8 2.8 10.0 7.3 5.6 4.7 7.2 7.1 1.8 0.0 2.3 10.0 2.9 9.8 8.9 101.9 7.9 6.3 6.0 1.8 7.4 45.4 10.5 2.3 6.0 1.5 4.7 3.8 7.0 8.2 2.9 9.7 3.3 33.4 5.7 4.1 8.7 6.9 22.9 6.8 7.9 8.8 14.0 9.3 14.5 20.6 39.7 28.3 9.2 1.8 7.2 3.8 9.1 6.8 8.3 7.8 9.7 0.0 8.9 7.8 66.7 13.0 1.6 5.1 2.2 9.0 4.6 4.8 7.7 LRRFIP2 HUFI-2 ENSG00000093167 "LRR binding FLII interacting protein 2" Q9Y608 3 37052626-37183689 "Predicted intracellular proteins, Transcription factors" "Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 516.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035956, HPA042023" Uncertain Approved "Plasma membrane,Actin filaments" NA NA 150000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Actin filaments" "HPA035956: AB_10671238, HPA042023: AB_2677802" "unprognostic (2.03e-3)" "prognostic favorable (6.31e-4)" "unprognostic (1.16e-2)" "unprognostic (7.90e-2)" "unprognostic (2.48e-1)" "unprognostic (2.97e-1)" "unprognostic (5.41e-2)" "unprognostic (1.82e-1)" "unprognostic (3.09e-2)" "unprognostic (2.56e-2)" "unprognostic (4.99e-3)" "unprognostic (1.98e-1)" "unprognostic (4.13e-3)" "unprognostic (2.62e-1)" "unprognostic (1.37e-1)" "unprognostic (4.84e-3)" "unprognostic (3.76e-2)" 23.4 24.0 43.7 20.1 46.9 44.3 22.3 43.6 49.0 46.0 33.6 38.3 35.4 31.8 19.7 52.6 25.8 22.0 75.8 38.8 44.4 24.0 48.5 27.0 18.1 43.4 42.0 27.4 19.2 33.3 18.6 20.8 44.8 41.0 34.2 36.0 28.5 24.3 97.9 37.0 36.2 31.5 41.0 45.0 26.5 71.8 46.4 18.8 27.5 45.3 23.2 24.2 40.9 60.9 56.6 30.8 34.9 27.7 45.5 69.3 30.5 149.9 148.2 82.6 94.3 29.0 25.3 22.2 24.0 145.4 40.8 28.8 25.8 74.2 134.3 49.7 20.2 39.8 44.0 28.6 64.8 31.9 23.3 31.1 52.1 107.8 110.4 45.8 58.2 34.0 32.3 37.8 69.5 14.4 27.2 17.0 23.0 23.0 39.2 13.0 99.2 22.6 58.4 21.7 12.6 19.9 57.9 53.0 49.4 28.0 30.6 32.6 56.5 63.1 42.6 93.4 71.5 29.1 57.1 33.9 37.1 28.1 91.4 20.5 21.4 33.8 8.8 14.9 11.3 9.7 9.3 9.5 14.1 8.5 6.8 8.3 19.2 16.9 26.9 7.9 13.0 11.7 43.7 46.9 43.6 49.0 38.8 44.4 43.4 42.0 44.8 41.0 46.4 60.9 47.8 28.9 36.5 98.6 29.1 136.1 143.0 41.3 113.8 36.3 64.7 53.2 123.1 38.6 53.7 23.9 29.2 29.2 28.7 117.2 64.6 89.8 516.2 78.9 44.0 59.9 54.0 60.0 169.8 94.3 46.1 57.4 37.8 127.3 52.6 29.4 56.7 58.8 24.9 122.8 197.7 45.6 28.5 35.6 128.3 330.7 42.3 48.2 74.7 62.8 67.7 51.9 30.9 130.7 309.0 109.9 90.1 57.6 45.8 325.6 125.8 46.1 36.2 51.9 39.5 32.4 72.8 159.9 73.4 139.3 170.5 39.3 34.1 90.0 66.0 303.2 LRSAM1 "CMT2P, FLJ31641, RIFLE, TAL" ENSG00000148356 "Leucine rich repeat and sterile alpha motif containing 1" Q6UWE0 9 127451489-127503499 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Autophagy, Protein transport, Transport, Ubl conjugation pathway" Transferase "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 32.0;Excitatory neurons: 28.6;Inhibitory neurons: 26.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021403, HPA021844, CAB037304" Supported Approved Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "CAB037304: AB_2138198, HPA021403: AB_1853366, HPA021844: AB_1853368" "unprognostic (8.83e-2)" "unprognostic (3.13e-1)" "unprognostic (7.48e-3)" "unprognostic (4.15e-3)" "unprognostic (9.42e-2)" "unprognostic (2.05e-1)" "unprognostic (1.64e-1)" "unprognostic (5.00e-2)" "unprognostic (1.66e-1)" "unprognostic (2.72e-2)" "prognostic favorable (6.78e-6)" "unprognostic (1.27e-1)" "prognostic favorable (5.72e-4)" "unprognostic (1.94e-2)" "unprognostic (3.26e-1)" "unprognostic (9.07e-2)" "unprognostic (3.33e-2)" 7.2 9.8 8.6 3.4 8.6 2.0 7.3 7.3 12.5 10.7 5.2 16.5 3.4 9.0 5.9 8.7 7.8 3.9 17.3 8.8 8.8 9.0 8.8 7.4 4.5 11.1 7.6 10.7 5.7 6.9 9.0 3.4 11.4 9.1 2.6 2.3 7.5 5.6 13.5 21.2 9.1 5.0 7.0 9.5 9.5 4.3 7.9 3.4 8.8 7.2 3.2 12.3 10.2 9.0 5.7 10.8 4.8 10.7 9.8 9.1 8.3 5.3 8.1 10.0 7.6 8.9 5.9 9.8 5.9 9.9 3.6 18.7 7.8 13.3 3.8 11.5 5.3 5.2 9.0 10.2 9.4 6.2 7.3 6.1 7.9 6.1 12.2 10.7 11.2 7.6 4.8 7.6 4.5 17.6 3.9 4.5 4.7 17.4 9.3 7.1 5.6 18.4 11.5 5.1 9.8 9.2 4.1 12.6 8.8 4.3 26.5 3.2 10.2 4.6 5.6 4.2 2.5 6.2 7.9 1.1 9.1 4.5 2.6 18.5 4.8 21.3 3.7 6.5 4.7 3.7 2.8 3.5 6.1 2.7 1.1 1.4 4.0 1.3 6.8 3.6 2.3 3.8 8.6 8.6 7.3 12.5 8.8 8.8 11.1 7.6 11.4 7.0 7.9 9.0 5.3 9.6 3.9 32.0 5.1 1.1 3.1 2.9 4.6 6.7 5.2 5.0 20.4 4.3 7.3 0.0 6.2 5.0 5.3 6.0 5.9 7.1 0.6 3.6 4.7 4.8 1.2 2.5 28.6 1.4 2.1 4.9 12.2 4.6 9.5 6.6 3.3 7.1 6.3 11.8 26.9 5.8 14.2 5.6 3.7 1.2 2.8 7.4 3.6 10.3 7.4 4.7 3.1 18.1 21.0 4.7 5.0 5.3 3.9 5.0 6.6 5.8 6.0 5.2 0.0 5.1 6.0 5.7 3.6 5.8 2.7 7.0 5.6 3.9 4.8 3.3 LSM14B "bA11M20.3, C20orf40, FAM61B, FLJ25473, FT005, LSM13, RAP55B" ENSG00000149657 "LSM family member 14B" Q9BX40 20 62122461-62135374 "Predicted intracellular proteins" "Translation regulation" "Developmental protein, Ribonucleoprotein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 16 "Early spermatids: 215.2;Late spermatids: 560.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "eosinophil: 2.2" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041274, HPA061189" Approved Supported Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 21: Non-specific - Transcription" "Cluster 39: CACO-2 - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "HPA041274: AB_2677388, HPA061189: AB_2684448" "unprognostic (2.24e-1)" "unprognostic (2.35e-1)" "unprognostic (2.89e-1)" "unprognostic (1.85e-2)" "unprognostic (1.20e-1)" "unprognostic (1.42e-1)" "prognostic unfavorable (3.61e-5)" "unprognostic (4.99e-2)" "unprognostic (2.28e-1)" "unprognostic (5.43e-2)" "unprognostic (4.93e-3)" "unprognostic (4.69e-2)" "unprognostic (3.34e-3)" "unprognostic (6.61e-2)" "unprognostic (2.00e-1)" "unprognostic (4.53e-3)" "unprognostic (1.98e-1)" 19.7 23.9 29.3 21.0 30.1 26.7 19.8 39.5 34.5 27.5 21.6 27.4 23.4 31.2 14.2 31.6 25.7 14.5 37.7 32.3 24.1 19.0 24.4 19.3 23.5 24.2 26.6 37.4 30.4 21.3 24.9 14.9 25.9 22.0 14.3 31.2 23.7 17.4 71.6 34.6 22.8 17.6 23.2 21.7 23.3 51.9 27.1 28.8 20.9 45.3 17.8 26.5 27.3 27.2 44.4 41.6 65.0 62.5 29.0 30.3 55.3 46.0 34.1 93.7 40.9 123.4 30.1 46.5 51.7 31.9 67.9 62.9 31.5 39.6 46.4 19.2 22.9 112.3 57.8 74.3 40.0 48.6 65.1 26.1 70.4 39.1 36.1 36.7 24.3 53.8 61.4 32.7 33.0 58.7 81.2 72.7 40.2 70.8 61.0 104.3 128.5 36.9 25.5 51.7 88.8 77.0 83.9 73.5 61.3 37.5 91.6 60.9 31.8 132.9 90.0 69.1 47.3 40.8 52.1 56.8 58.5 31.7 43.4 0.0 0.4 2.2 0.3 0.3 0.1 0.5 0.2 0.4 0.3 0.5 0.2 0.3 0.6 0.0 0.2 0.4 0.2 0.1 29.3 30.1 39.5 34.5 32.3 24.1 24.2 26.6 25.9 23.2 27.1 27.2 8.6 9.6 6.8 9.1 7.3 9.7 3.5 4.7 5.2 15.1 8.4 7.1 22.8 7.2 7.9 1.8 8.4 6.4 15.3 13.5 1.9 5.0 215.2 13.3 14.1 8.0 13.9 9.5 6.2 5.3 6.0 7.5 8.2 10.3 5.1 14.8 5.0 11.6 8.6 8.4 6.8 12.0 6.1 13.2 6.8 560.0 13.4 8.8 3.6 7.5 8.2 17.2 7.2 5.0 8.4 7.1 8.2 15.8 4.7 9.2 9.7 6.7 12.1 20.3 0.0 9.5 6.4 11.2 23.1 7.6 10.1 5.2 6.9 13.4 12.4 3.0 LSR "ILDR3, LISCH7" ENSG00000105699 "Lipolysis stimulated lipoprotein receptor" Q86X29 19 35248330-35267964 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 144.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 335.6;Ductal cells: 260.5;Exocrine glandular cells: 278.9;Pancreatic endocrine cells: 336.0;Paneth cells: 273.6;Syncytiotrophoblasts: 248.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 500.5;CACO-2: 215.6;CAPAN-2: 225.3;HaCaT: 203.9;OE19: 300.4;RT4: 198.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007270, HPA075309" Approved Supported "Plasma membrane" NA NA 3500000 "Cluster 44: Non-specific - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "HPA007270: AB_1079253, HPA075309: " "unprognostic (3.90e-1)" "unprognostic (1.12e-1)" "unprognostic (2.34e-2)" "unprognostic (2.67e-3)" "unprognostic (2.28e-2)" "unprognostic (6.07e-3)" "unprognostic (1.55e-1)" "unprognostic (9.84e-2)" "unprognostic (2.17e-1)" "unprognostic (2.70e-2)" "unprognostic (2.23e-2)" "unprognostic (3.42e-2)" "prognostic favorable (8.09e-4)" "unprognostic (1.64e-1)" "unprognostic (1.84e-1)" "unprognostic (2.99e-2)" "unprognostic (1.54e-2)" 15.7 31.3 15.7 17.8 13.6 3.6 25.4 13.2 14.7 20.4 39.0 96.9 85.0 14.4 13.9 60.0 29.7 36.4 7.7 12.5 13.2 28.9 144.8 30.0 14.4 17.1 14.8 6.4 114.2 16.8 27.3 46.9 15.5 25.6 43.7 8.6 69.4 18.5 4.4 51.9 75.0 5.3 12.9 17.9 133.1 27.2 17.7 6.6 32.9 2.7 14.1 29.9 29.3 14.8 500.5 8.1 0.7 1.0 1.4 0.5 86.8 1.2 1.9 2.2 1.6 215.6 225.3 19.6 73.0 1.3 7.2 203.9 44.3 75.0 0.3 30.1 82.6 0.2 6.5 96.1 1.7 0.3 0.9 1.0 81.2 2.0 24.2 1.0 0.8 0.6 80.2 17.2 1.1 177.4 0.9 1.1 69.0 300.4 3.2 3.8 0.8 54.6 46.2 198.2 37.7 1.4 40.9 130.5 35.8 21.7 112.5 2.6 0.4 3.9 44.7 3.1 2.2 27.2 52.5 45.7 3.4 0.8 12.4 6.4 0.2 0.1 2.5 0.0 2.6 4.3 5.8 5.4 0.1 3.0 4.2 4.9 0.0 5.6 0.0 0.2 4.1 2.9 15.7 13.6 13.2 14.7 12.5 13.2 17.1 14.8 15.5 12.9 17.7 14.8 38.2 16.0 21.7 0.3 26.3 51.7 123.4 90.7 50.1 2.1 60.9 49.7 5.6 78.6 71.2 36.8 16.7 210.3 4.7 335.6 11.7 260.5 9.4 41.7 27.4 44.6 56.4 3.2 0.8 278.9 93.0 11.9 214.1 61.5 31.1 30.3 20.3 89.7 21.7 0.0 0.9 145.5 73.2 2.2 14.3 2.9 6.5 4.6 14.2 22.5 7.2 11.5 3.1 1.5 0.8 336.0 273.6 3.4 41.1 113.6 117.8 24.6 43.8 12.3 0.0 4.1 24.4 7.9 19.1 57.2 51.7 248.0 24.3 3.4 124.2 206.3 LY9 "CD229, hly9, mLY9, SLAMF3" ENSG00000122224 "Lymphocyte antigen 9" Q9HBG7 1 160796074-160828261 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Cell adhesion, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 11.5;intestine: 12.0;lymphoid tissue: 31.1" "Cell type enhanced" "Detected in some" "B-cells: 244.0;dendritic cells: 36.2;Melanocytes: 71.2;Plasma cells: 102.5;T-cells: 44.8" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "gdT-cell: 112.9;MAIT T-cell: 113.5;memory B-cell: 56.1;memory CD4 T-cell: 97.6;memory CD8 T-cell: 109.8;naive B-cell: 52.8;naive CD4 T-cell: 109.6;naive CD8 T-cell: 112.3;plasmacytoid DC: 72.8;T-reg: 80.3" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 14.3;JURKAT: 14.1;Karpas-707: 28.0;U-266/70: 70.7;U-266/84: 29.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA050917 Approved Approved "Plasma membrane,Centriolar satellite" NA NA 43000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane" "Centriolar satellite" "HPA050917: AB_2681272" "unprognostic (8.04e-4)" "unprognostic (2.31e-5)" "unprognostic (8.08e-3)" "unprognostic (1.20e-3)" "unprognostic (9.83e-3)" "unprognostic (1.87e-5)" "unprognostic (1.16e-2)" "unprognostic (3.84e-3)" "unprognostic (1.23e-2)" "unprognostic (2.89e-3)" "unprognostic (1.64e-1)" "unprognostic (2.30e-1)" "unprognostic (2.70e-3)" "unprognostic (8.69e-2)" "unprognostic (9.47e-2)" "unprognostic (3.49e-2)" "unprognostic (6.88e-2)" 2.4 0.9 0.1 13.7 0.2 11.5 2.0 0.1 0.2 0.8 0.2 3.9 4.0 0.6 0.4 0.9 0.9 2.5 0.5 0.1 0.2 1.1 2.3 3.8 30.2 0.3 0.2 0.6 0.2 0.0 0.2 0.3 0.2 1.1 3.8 0.0 7.1 0.4 0.3 0.8 12.0 0.5 0.3 26.7 6.0 0.2 0.2 25.5 1.4 0.2 31.1 3.5 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 14.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 14.1 0.0 28.0 0.0 0.0 2.3 0.5 0.1 0.8 0.0 1.6 0.0 3.7 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 70.7 29.3 0.3 0.0 4.0 0.0 1.2 0.8 0.4 112.9 1.1 113.5 56.1 97.6 109.8 5.2 52.8 109.6 112.3 2.4 22.2 0.8 72.8 80.3 53.5 0.1 0.2 0.1 0.2 0.1 0.2 0.3 0.2 0.2 0.3 0.2 0.2 0.4 0.0 1.8 0.3 244.0 1.0 0.5 0.1 0.0 0.0 0.4 0.8 0.9 0.0 0.0 0.0 0.0 0.1 36.2 0.1 0.0 0.0 0.1 0.1 0.1 0.7 1.2 28.0 0.1 0.2 0.0 1.4 0.5 0.1 0.0 0.0 1.8 0.4 1.9 0.0 0.1 0.0 0.0 3.2 31.9 0.0 0.0 6.3 71.2 1.9 2.1 0.0 22.6 0.0 0.1 0.1 0.0 0.0 102.5 0.2 0.0 0.3 0.0 0.0 0.0 0.5 0.6 0.0 0.1 0.5 1.0 0.1 44.8 0.0 0.3 0.3 MACROH2A2 H2AFY2 ENSG00000099284 "MacroH2A.2 histone" Q9P0M6 10 70052544-70112282 "Predicted intracellular proteins" "Chromatin regulator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 7.1;Fibroblasts: 1.7;Hofbauer cells: 4.9;Syncytiotrophoblasts: 1.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 12.6" "Group enriched" "Detected in many" 5 "dendritic cells: 12.6;monocytes: 5.4" "Cell line enhanced" "Detected in many" "AF22: 173.9;AN3-CA: 111.5;SCLC-21H: 137.0;SH-SY5Y: 132.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035865, HPA041189" Enhanced Supported Nucleoplasm No No "Cluster 28: Myeloid DCs - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 12: NES - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" Nucleoplasm "HPA035865: AB_10672099, HPA041189: AB_2677357" "unprognostic (1.62e-2)" "unprognostic (9.62e-2)" "unprognostic (1.46e-2)" "unprognostic (1.46e-2)" "unprognostic (7.71e-3)" "unprognostic (1.85e-1)" "unprognostic (3.44e-2)" "unprognostic (5.37e-2)" "unprognostic (1.67e-1)" "unprognostic (9.17e-2)" "unprognostic (7.32e-2)" "unprognostic (1.80e-2)" "unprognostic (1.31e-2)" "unprognostic (3.27e-2)" "unprognostic (4.58e-2)" "unprognostic (8.78e-2)" "unprognostic (4.66e-2)" 3.8 3.2 5.3 5.6 4.5 1.9 10.2 7.3 6.3 14.7 3.3 10.8 9.5 18.3 11.6 17.4 16.5 8.7 13.5 4.1 4.9 15.2 5.2 5.6 4.9 3.8 3.9 13.3 7.8 14.9 14.0 2.1 3.7 13.1 10.5 3.2 10.9 14.4 6.5 10.7 10.1 15.3 3.6 2.7 8.6 11.8 4.2 7.4 10.2 8.6 7.2 13.2 11.8 4.4 4.7 31.1 173.9 111.5 2.5 5.1 0.1 8.6 0.3 16.2 11.0 0.5 55.8 0.0 23.5 2.8 9.1 27.4 15.3 44.8 5.1 81.1 63.4 0.0 0.2 59.1 11.2 1.9 0.8 8.1 30.4 6.4 8.5 23.4 0.0 6.3 0.1 0.6 15.7 37.5 0.2 0.9 74.8 0.2 44.9 0.4 0.5 0.6 30.7 34.0 137.0 132.4 28.6 0.2 0.0 35.2 41.5 20.3 0.0 0.3 32.3 12.4 6.2 0.4 0.1 0.3 0.0 0.2 0.3 1.6 2.4 0.8 0.6 5.4 1.1 0.3 0.9 0.8 12.6 0.3 0.8 0.9 1.4 1.1 3.0 0.2 0.5 1.6 5.3 4.5 7.3 6.3 4.1 4.9 3.8 3.9 3.7 3.6 4.2 4.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.4 1.7 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 MAD2L1 "HSMAD2, MAD2" ENSG00000164109 "Mitotic arrest deficient 2 like 1" Q13257 4 120055623-120066858 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.9;lymphoid tissue: 5.7" "Cell type enhanced" "Detected in many" "Erythroid cells: 81.8;Extravillous trophoblasts: 119.2;Spermatocytes: 127.8;Spermatogonia: 76.2" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003348 Uncertain Approved Nucleoplasm NA Yes "Cluster 20: T-cells - T-cell receptor" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA003348: AB_10603014" "unprognostic (4.08e-3)" "unprognostic (7.31e-2)" "unprognostic (5.17e-3)" "unprognostic (1.10e-2)" "unprognostic (1.27e-1)" "unprognostic (5.54e-2)" "prognostic unfavorable (5.15e-5)" "prognostic unfavorable (2.17e-4)" "unprognostic (6.74e-3)" "unprognostic (1.47e-1)" "unprognostic (3.20e-3)" "unprognostic (3.87e-3)" "prognostic unfavorable (3.07e-11)" "unprognostic (3.06e-2)" "unprognostic (4.05e-1)" "unprognostic (1.03e-1)" "unprognostic (9.70e-2)" 0.3 0.4 0.5 2.1 0.6 5.9 1.2 0.8 0.7 0.5 0.2 2.2 1.8 0.7 0.3 1.6 1.4 0.4 0.5 0.5 0.5 0.4 0.5 0.4 4.0 0.4 0.4 0.5 0.2 0.4 0.1 1.4 0.5 0.6 2.6 1.0 0.3 0.5 0.2 1.0 1.9 0.8 0.4 0.8 0.9 2.3 0.4 5.7 0.4 0.2 3.6 0.7 0.5 0.6 27.2 11.6 26.9 17.5 2.8 3.4 11.5 21.0 11.8 21.5 16.5 15.7 16.3 39.6 6.8 7.6 9.5 7.1 27.1 16.1 30.0 18.8 18.8 22.0 10.5 14.9 0.8 36.3 12.0 1.9 2.3 14.6 9.1 5.4 12.6 16.4 26.7 22.0 11.4 12.0 35.0 15.6 18.3 14.1 13.0 17.8 35.9 16.2 8.7 10.3 28.4 20.1 10.5 12.8 6.5 12.9 8.4 13.0 7.8 14.2 16.1 14.6 27.0 20.1 23.2 25.7 13.3 18.4 19.1 0.9 0.1 0.1 0.4 0.1 0.6 0.5 1.2 1.0 0.1 0.4 1.1 1.1 0.3 0.9 0.2 0.7 1.3 0.5 0.5 0.6 0.8 0.7 0.5 0.5 0.4 0.4 0.5 0.4 0.4 0.6 2.4 0.0 1.3 1.0 11.5 17.3 7.3 23.5 4.0 9.7 7.2 8.3 3.4 1.5 6.0 7.3 2.1 52.0 7.6 7.5 0.0 3.4 2.4 31.3 6.0 5.4 1.8 81.8 1.3 1.5 119.2 13.7 8.6 7.8 15.2 34.6 3.9 2.9 27.9 20.2 1.2 13.7 36.7 7.3 13.4 4.8 4.7 6.1 8.8 0.0 3.1 12.3 5.2 0.5 1.0 1.6 3.7 1.5 33.1 5.0 3.7 7.2 12.9 3.8 13.1 7.3 14.9 127.8 76.2 26.0 8.9 10.8 20.1 11.9 29.2 8.7 MAP6 "FLJ41346, KIAA1878, MAP6-N, STOP" ENSG00000171533 "Microtubule associated protein 6" Q96JE9 11 75586918-75669038 "Predicted intracellular proteins" Transport Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 76.8;retina: 96.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 81.2;Cone photoreceptor cells: 158.4;Excitatory neurons: 75.8;Horizontal cells: 50.5;Inhibitory neurons: 43.3;Late spermatids: 41.9" "Cancer enhanced" "Detected in many" "glioma: 9.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "AF22: 37.8;CACO-2: 38.1;HDLM-2: 21.5;SCLC-21H: 62.4;SH-SY5Y: 31.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015442, CAB022600, HPA039061, HPA039062" Enhanced Uncertain "Plasma membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane" "CAB015442: AB_2140997, CAB022600: , HPA039061: AB_2676325, HPA039062: AB_2676326" "unprognostic (3.04e-2)" "unprognostic (6.18e-2)" "unprognostic (3.15e-2)" "unprognostic (9.07e-2)" "unprognostic (7.54e-2)" "unprognostic (4.49e-2)" "unprognostic (8.29e-2)" "unprognostic (2.51e-2)" "unprognostic (5.99e-2)" "unprognostic (7.99e-2)" "prognostic favorable (3.41e-4)" "prognostic favorable (9.15e-4)" "unprognostic (2.43e-2)" "unprognostic (3.96e-3)" "unprognostic (8.09e-3)" "unprognostic (1.77e-1)" "unprognostic (2.03e-1)" 4.8 19.0 68.3 2.0 68.0 0.0 3.5 50.7 70.6 10.6 64.4 23.0 1.7 18.1 21.0 4.2 40.7 6.4 8.6 67.7 71.5 17.0 1.2 7.8 0.7 70.2 64.6 8.0 3.6 22.0 76.8 1.5 70.8 17.8 3.5 96.1 3.6 21.1 1.0 8.1 4.8 13.1 52.9 2.4 10.7 18.6 68.5 0.8 7.9 1.3 0.5 7.1 8.4 59.7 0.2 0.7 37.8 0.1 0.1 0.0 0.0 3.8 0.2 0.3 0.0 38.1 0.1 0.6 1.4 6.3 1.3 0.0 3.4 0.5 0.0 21.5 0.5 0.0 0.0 0.0 1.0 0.0 0.0 2.1 0.5 0.1 0.2 5.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 5.9 0.0 2.9 0.0 0.0 0.1 0.1 0.5 62.4 31.7 4.6 0.0 0.0 0.8 0.0 0.0 0.9 0.0 0.1 0.1 0.5 0.0 0.0 0.0 6.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 68.3 68.0 50.7 70.6 67.7 71.5 70.2 64.6 70.8 52.9 68.5 59.7 1.2 3.2 3.7 25.8 0.1 0.8 1.7 0.7 0.0 81.2 0.8 1.8 8.4 1.5 3.1 11.0 158.4 0.2 0.2 0.0 1.9 0.1 27.7 28.2 4.6 1.6 13.1 0.0 75.8 0.2 0.0 2.9 0.0 0.8 0.0 0.8 2.2 0.3 0.1 50.5 43.3 0.0 6.1 0.0 1.1 41.9 7.5 0.3 5.4 1.9 0.0 18.7 0.0 13.0 13.3 0.2 0.0 18.4 0.1 1.4 0.0 1.2 25.4 10.2 0.0 1.9 5.7 23.5 4.3 0.1 0.4 0.0 0.3 0.1 0.0 0.4 MAPK13 "p38delta, PRKM13, SAPK4" ENSG00000156711 "Mitogen-activated protein kinase 13" O15264 6 36127809-36144524 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 102.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 146.2;Late spermatids: 282.5;Proximal enterocytes: 178.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HBEC3-KT: 63.8;RPMI-8226: 40.2;RT4: 47.0" "Low region specificity" "Detected in single" "Region enriched" "Detected in all" 14 "cerebellum: 37.5" "HPA007667, CAB025854" Enhanced Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Cytosol" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 30: Mammary glandular cells - Lactation" "Nucleoplasm, Nucleoli, Nucleoli rim, Cytosol" "CAB025854: , HPA007667: AB_1079867" "unprognostic (6.36e-2)" "unprognostic (6.88e-2)" "unprognostic (2.93e-1)" "unprognostic (6.64e-3)" "unprognostic (1.13e-2)" "unprognostic (4.80e-2)" "unprognostic (4.30e-3)" "unprognostic (5.28e-2)" "unprognostic (1.77e-1)" "unprognostic (2.14e-2)" "unprognostic (1.57e-1)" "unprognostic (7.21e-2)" "prognostic favorable (9.00e-4)" "unprognostic (3.12e-2)" "unprognostic (1.70e-1)" "unprognostic (2.21e-2)" "unprognostic (1.41e-1)" 8.7 55.9 3.1 8.8 3.0 9.4 14.2 0.5 4.4 18.6 0.0 44.6 30.9 3.4 11.5 102.4 7.6 7.5 2.5 2.9 2.2 17.3 6.7 23.8 7.9 0.6 0.0 5.4 47.7 38.9 33.3 5.6 0.2 16.7 24.4 2.7 49.5 15.5 1.2 74.1 40.1 1.9 0.1 16.1 24.1 40.0 4.2 6.9 18.9 1.0 12.4 12.2 39.3 2.7 31.4 0.3 0.7 0.5 2.4 11.2 4.3 3.3 0.4 0.3 0.8 22.3 28.4 7.0 2.0 2.5 4.6 24.4 0.3 63.8 0.7 20.0 7.9 0.2 1.2 22.8 4.0 0.4 2.2 9.2 25.9 4.3 1.0 4.5 4.1 1.2 0.6 9.4 0.9 12.7 0.4 2.6 0.4 30.9 0.4 21.0 0.5 40.2 11.6 47.0 30.5 0.7 2.5 0.5 0.2 1.3 33.0 4.1 6.3 2.4 0.4 1.0 0.7 0.8 12.7 2.3 0.1 1.3 0.2 7.6 0.4 6.5 18.3 0.1 12.3 13.9 14.5 15.4 0.1 22.0 12.8 14.4 4.6 3.8 0.1 0.2 38.0 8.6 3.1 3.0 0.5 4.4 2.9 2.2 0.6 0.0 0.2 0.1 4.2 2.7 1.5 28.9 33.0 1.0 16.4 27.3 43.5 24.9 15.4 0.7 58.8 17.7 1.7 25.8 27.3 29.5 6.2 55.3 14.9 146.2 15.6 56.9 110.3 9.1 2.8 2.1 65.5 0.0 10.0 115.9 11.8 5.0 32.1 26.2 2.5 21.1 1.1 1.7 40.3 0.0 6.7 83.2 34.6 6.8 3.3 282.5 7.2 8.8 17.8 3.7 14.2 2.1 21.6 1.5 1.2 103.6 102.2 9.8 11.4 37.1 178.4 11.5 3.7 2.4 0.0 2.2 3.4 56.6 2.9 62.6 53.3 32.3 18.5 2.5 93.0 59.9 MAPK4 "Erk3-related, Erk4, PRKM4" ENSG00000141639 "Mitogen-activated protein kinase 4" P31152 18 50560087-50731826 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 81.9;parathyroid gland: 51.0" "Cell type enhanced" "Detected in some" "Astrocytes: 202.7;Excitatory neurons: 105.2;Inhibitory neurons: 58.5;Late spermatids: 66.4;Muller glia cells: 62.6" "Cancer enriched" "Detected in many" 4 "glioma: 15.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 2.3;HeLa: 3.3;NTERA-2: 2.2;SCLC-21H: 11.6;SH-SY5Y: 2.8;SK-MEL-30: 1.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007461 Approved "Nucleoplasm,Golgi apparatus,Midbody" Yes NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Golgi apparatus" Midbody "HPA007461: AB_1079308" "unprognostic (4.12e-2)" "unprognostic (3.24e-2)" "unprognostic (3.60e-1)" "unprognostic (1.42e-3)" "unprognostic (5.17e-2)" "unprognostic (1.84e-2)" "unprognostic (6.32e-2)" "unprognostic (2.08e-2)" "unprognostic (8.24e-2)" "unprognostic (1.61e-1)" "unprognostic (4.38e-3)" "unprognostic (2.16e-1)" "unprognostic (3.44e-7)" "unprognostic (1.96e-4)" "unprognostic (5.99e-4)" "unprognostic (2.31e-2)" "unprognostic (1.82e-1)" 0.9 26.8 56.5 0.2 79.9 0.0 0.8 56.4 46.0 1.5 28.0 6.8 0.6 0.8 3.1 2.3 1.5 1.8 22.1 41.6 57.5 3.3 4.5 2.3 0.0 65.4 70.0 2.9 1.4 51.0 17.8 2.6 56.7 5.0 0.8 22.6 0.9 9.8 1.5 1.3 1.6 1.8 48.8 0.1 2.1 2.4 81.9 7.3 6.2 1.5 0.0 4.6 1.3 38.7 0.0 0.0 1.0 0.6 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 1.1 1.1 3.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.7 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 11.6 2.8 0.0 0.8 1.9 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 56.5 79.9 56.4 46.0 41.6 57.5 65.4 70.0 56.7 48.8 81.9 38.7 0.4 9.6 0.0 202.7 0.0 0.0 0.4 0.0 0.0 11.4 0.9 1.1 22.9 1.5 0.0 0.0 0.0 4.6 0.0 0.0 5.9 0.9 30.1 0.0 0.0 0.3 0.0 0.0 105.2 0.0 0.3 1.0 0.0 0.0 0.0 0.7 0.0 1.0 0.4 5.0 58.5 0.0 0.0 0.0 0.0 66.4 0.9 0.1 0.0 7.5 0.0 62.6 0.0 18.6 1.9 0.4 0.0 1.5 0.0 0.7 0.0 0.2 0.0 1.0 0.0 1.0 0.7 0.8 0.6 0.0 0.0 1.8 0.0 0.4 0.0 0.1 MAPK6 "ERK3, HsT17250, p97MAPK, PRKM6" ENSG00000069956 "Mitogen-activated protein kinase 6" Q16659 15 51952106-52067375 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 218.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005184, HPA030262, HPA047825" Approved Supported Supported Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" Cytosol "CAB005184: AB_2140298, HPA030262: AB_10601868, HPA047825: " "unprognostic (6.61e-2)" "unprognostic (1.75e-2)" "unprognostic (5.05e-2)" "unprognostic (3.40e-3)" "unprognostic (2.72e-1)" "unprognostic (5.52e-2)" "unprognostic (6.13e-2)" "unprognostic (2.32e-3)" "unprognostic (3.99e-2)" "unprognostic (8.54e-2)" "unprognostic (3.68e-2)" "unprognostic (3.90e-2)" "unprognostic (3.27e-3)" "unprognostic (2.03e-1)" "unprognostic (1.72e-1)" "unprognostic (3.07e-2)" "unprognostic (2.31e-2)" 10.9 7.0 8.6 12.1 11.1 32.4 13.9 14.5 13.3 15.3 7.6 20.3 17.5 16.4 10.9 28.0 8.2 17.5 7.7 10.5 10.5 15.2 35.3 8.8 10.8 10.5 10.8 6.2 8.3 11.0 8.0 12.6 10.6 10.1 18.7 17.9 15.3 8.7 27.7 23.1 24.5 13.7 9.7 8.3 16.9 29.3 10.6 14.5 13.9 32.9 13.6 27.3 21.3 12.0 27.1 36.0 69.1 26.7 21.1 34.3 50.5 38.0 38.0 34.2 40.1 43.3 15.9 38.9 26.0 48.9 50.0 37.5 53.8 72.4 46.5 24.0 16.8 58.0 20.3 68.9 50.4 43.9 118.6 36.8 130.0 41.5 106.8 36.4 32.7 26.1 76.5 64.3 44.2 61.3 30.8 34.4 24.7 33.6 17.2 26.8 44.5 62.3 32.8 112.3 33.8 31.9 30.7 24.6 56.5 94.9 22.6 64.3 32.9 40.7 43.9 26.8 51.4 33.2 104.4 47.5 50.4 62.9 51.2 1.7 2.5 0.7 1.9 2.3 2.3 2.5 2.8 2.2 2.3 1.3 2.6 1.9 0.3 3.6 1.5 1.0 4.3 1.9 8.6 11.1 14.5 13.3 10.5 10.5 10.5 10.8 10.6 9.7 10.6 12.0 31.3 28.9 31.5 24.5 24.2 111.9 123.8 50.6 24.5 55.6 39.3 19.3 21.9 25.8 43.1 16.5 16.7 16.9 15.9 110.2 17.6 35.2 147.5 61.3 75.7 28.8 31.0 17.1 29.1 50.1 39.5 39.2 35.7 126.4 137.9 19.3 17.9 59.6 28.0 33.7 31.0 42.9 42.7 41.8 66.6 218.1 22.7 50.5 30.2 17.8 15.7 32.3 11.3 28.6 63.7 69.1 46.5 23.7 35.3 89.0 110.6 60.3 42.9 23.8 19.7 24.7 33.9 72.7 81.0 49.6 110.7 33.1 23.0 13.9 28.6 174.0 MAPK8IP2 "IB2, JIP2, PRKM8IPL" ENSG00000008735 "Mitogen-activated protein kinase 8 interacting protein 2" Q13387 22 50600793-50613981 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 84.0;pituitary gland: 35.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 57.8;Enteroendocrine cells: 32.3;Horizontal cells: 99.3;Rod photoreceptor cells: 26.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 19.3;HEK 293: 11.0;SCLC-21H: 15.7;SH-SY5Y: 19.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034780 Uncertain NA NA "Cluster 65: Brain - Ion transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 62: Horizontal cells - Visual perception" "HPA034780: AB_10670283" "unprognostic (7.82e-2)" "unprognostic (7.62e-2)" "unprognostic (3.48e-2)" "unprognostic (1.31e-2)" "unprognostic (5.80e-2)" "unprognostic (6.72e-2)" "unprognostic (1.18e-1)" "unprognostic (2.90e-1)" "unprognostic (5.23e-2)" "unprognostic (9.19e-2)" "unprognostic (8.57e-3)" "unprognostic (8.78e-3)" "unprognostic (6.33e-3)" "unprognostic (6.77e-2)" "unprognostic (1.72e-1)" "unprognostic (5.29e-2)" "unprognostic (4.75e-2)" 1.4 9.2 54.7 0.3 50.2 0.0 1.4 27.5 67.8 1.4 0.0 2.1 0.2 2.1 0.3 1.2 1.5 0.0 0.4 53.7 35.1 0.7 0.5 0.5 0.0 78.0 27.0 7.0 1.8 2.0 35.2 0.3 84.0 1.9 0.1 9.6 2.8 0.2 0.3 1.5 1.0 0.2 18.6 0.8 1.5 7.1 39.4 0.2 1.0 0.1 0.0 0.3 1.0 49.2 0.3 1.1 4.7 4.1 0.4 0.0 3.7 0.0 0.0 1.0 0.6 2.4 0.8 0.6 1.0 0.0 19.3 0.0 6.6 0.0 0.0 0.3 11.0 0.0 0.4 1.2 0.5 0.0 0.8 0.3 5.5 0.0 0.1 0.0 0.0 0.1 1.1 1.8 0.0 0.0 0.0 0.0 3.4 0.8 1.8 1.1 0.7 0.0 0.0 0.1 15.7 19.8 3.7 4.6 0.2 0.9 0.9 0.0 0.0 0.1 0.1 0.6 0.0 1.1 3.1 0.5 0.5 0.5 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.7 50.2 27.5 67.8 53.7 35.1 78.0 27.0 84.0 18.6 39.4 49.2 0.6 3.2 2.0 6.5 0.1 0.4 1.6 0.5 0.6 57.8 2.3 3.9 2.3 2.8 2.7 0.0 16.7 0.2 0.0 0.5 0.0 3.0 0.6 0.7 1.7 0.7 32.3 0.0 15.6 2.5 1.1 0.7 0.0 1.5 0.0 0.5 0.0 0.3 0.1 99.3 13.1 0.5 4.1 0.0 0.4 1.8 5.9 0.3 7.2 3.7 0.2 11.2 0.0 6.0 3.2 0.7 0.1 0.7 0.1 1.2 0.3 0.7 0.3 26.7 0.0 1.3 1.0 3.4 2.7 0.6 0.6 1.1 0.3 0.5 0.6 0.5 MAPKAPK3 "3pK, MAPKAP3, MK-3, MK3" ENSG00000114738 "MAPK activated protein kinase 3" Q16644 3 50611520-50649291 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 106.5;heart muscle: 256.3;skeletal muscle: 224.2;tongue: 284.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 226.6;Hofbauer cells: 102.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "dendritic cells: 142.8;granulocytes: 126.3;monocytes: 341.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058275 Supported Nucleoplasm NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 32: U-937 - Innate immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm "HPA058275: AB_2683663" "unprognostic (6.46e-3)" "unprognostic (1.84e-1)" "prognostic favorable (8.08e-5)" "unprognostic (1.17e-1)" "unprognostic (1.93e-1)" "unprognostic (9.96e-2)" "unprognostic (8.77e-3)" "unprognostic (7.68e-3)" "unprognostic (1.11e-1)" "unprognostic (5.87e-2)" "unprognostic (2.19e-3)" "unprognostic (1.01e-1)" "prognostic favorable (1.90e-8)" "unprognostic (2.15e-2)" "unprognostic (1.22e-1)" "unprognostic (1.86e-1)" "unprognostic (1.69e-1)" 15.3 43.3 18.0 29.8 19.6 106.5 15.8 19.2 19.2 15.0 21.3 19.7 30.2 11.3 10.3 49.6 15.1 12.1 256.3 18.0 19.7 40.0 18.7 28.2 21.7 23.6 20.5 14.2 36.2 47.2 23.5 13.9 22.5 18.4 20.0 4.7 27.7 12.6 224.2 53.4 24.2 15.9 21.6 25.3 27.6 9.2 21.1 42.0 41.2 284.3 24.2 20.3 22.2 21.6 99.6 30.3 12.4 35.9 18.4 45.7 27.9 23.8 33.7 35.7 30.3 47.1 90.2 39.8 23.5 79.5 88.5 34.6 85.9 92.7 31.9 88.3 22.3 209.5 40.6 43.5 36.8 152.1 106.4 36.9 57.0 83.1 112.2 35.6 31.9 70.2 59.7 25.4 76.1 40.5 65.3 153.3 46.4 34.6 127.0 28.5 29.9 60.1 165.5 56.2 23.0 16.5 21.3 58.9 27.7 20.6 37.8 93.4 23.8 28.1 64.5 146.4 59.5 17.2 33.7 33.1 148.3 234.7 11.8 45.3 169.5 126.3 27.6 271.6 27.3 15.1 30.9 32.1 142.8 8.8 23.9 27.8 104.4 42.1 341.5 91.2 28.0 132.6 18.0 19.6 19.2 19.2 18.0 19.7 23.6 20.5 22.5 21.6 21.1 21.6 3.5 9.6 14.0 8.5 8.6 11.3 26.9 14.0 19.4 1.1 15.3 12.3 226.6 15.7 10.4 11.0 0.0 6.0 38.1 16.2 64.6 45.6 34.5 3.4 2.7 7.1 6.0 19.1 0.3 30.4 7.4 14.9 11.7 5.4 36.2 8.3 5.3 14.2 102.1 0.0 0.7 15.4 10.2 68.0 23.9 86.2 7.2 59.4 7.2 0.0 76.6 17.1 41.2 0.5 2.0 76.2 15.6 3.4 12.7 30.9 30.7 35.4 5.7 2.3 26.3 9.7 12.0 4.1 4.6 34.2 20.2 5.1 24.3 22.0 28.2 33.5 MARCHF3 "MARCH-III, MARCH3, MGC48332, RNF173" ENSG00000173926 "Membrane associated ring-CH-type finger 3" Q86UD3 5 126867714-127030558 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Endocytosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Cytotrophoblasts: 43.8;Syncytiotrophoblasts: 98.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 10.5;naive B-cell: 12.1" "Lineage enriched" "Detected in many" 4 "B-cells: 12.1" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 40.4;HUVEC TERT2: 27.4;TIME: 33.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043406 Uncertain Supported Vesicles NA NA "Cluster 37: B-cells - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Vesicles "HPA043406: AB_10793947" "unprognostic (5.96e-3)" "unprognostic (1.46e-2)" "unprognostic (1.91e-2)" "unprognostic (4.21e-2)" "unprognostic (9.00e-3)" "unprognostic (1.17e-2)" "unprognostic (7.75e-3)" "unprognostic (9.41e-2)" "unprognostic (8.93e-2)" "unprognostic (2.05e-3)" "unprognostic (3.15e-2)" "unprognostic (1.82e-1)" "unprognostic (5.60e-6)" "unprognostic (7.74e-2)" "unprognostic (7.64e-2)" "unprognostic (1.05e-1)" "unprognostic (3.64e-1)" 5.6 2.8 6.1 2.9 5.6 3.7 2.6 5.3 4.1 0.9 1.9 5.3 0.9 1.4 0.0 1.4 1.5 5.2 7.8 3.9 5.7 0.8 0.7 2.4 2.5 11.5 7.1 1.1 2.4 0.3 2.4 1.7 7.9 0.6 5.6 7.4 4.6 0.2 6.5 5.8 2.4 2.9 8.3 1.6 2.4 5.6 7.8 1.3 1.4 3.3 2.1 7.6 0.7 8.5 0.4 1.8 3.9 2.1 3.4 3.2 1.2 14.2 5.9 11.1 16.3 1.9 0.8 3.8 1.3 1.9 2.4 1.1 4.9 2.5 15.3 0.8 4.7 12.2 3.2 1.9 5.6 5.0 3.0 2.4 0.7 40.4 4.8 2.6 27.4 0.6 5.1 0.7 9.3 1.3 0.5 2.3 3.3 3.0 4.6 1.5 15.5 1.2 0.9 2.0 1.3 0.9 3.3 0.5 1.6 1.9 2.9 5.0 33.5 2.2 1.8 12.6 1.6 1.9 2.3 2.3 8.3 3.8 2.0 0.0 0.2 2.8 0.5 0.4 0.1 10.5 0.6 0.3 0.1 12.1 2.3 0.5 0.8 2.3 0.3 0.7 2.9 0.8 6.1 5.6 5.3 4.1 3.9 5.7 11.5 7.1 7.9 8.3 7.8 8.5 3.8 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.4 0.0 0.0 0.0 0.0 43.8 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 3.2 5.8 0.0 0.0 0.0 0.0 0.0 0.0 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 98.6 0.6 0.0 0.0 0.0 MARK2 "EMK1, PAR-1, PAR-1B, Par1b" ENSG00000072518 "Microtubule affinity regulating kinase 2" Q7KZI7 11 63838928-63911020 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Differentiation, Wnt signaling pathway" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038790, HPA074905" Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" Nucleoplasm "HPA038790: AB_10674840, HPA074905: AB_2686722" "unprognostic (1.33e-2)" "unprognostic (2.45e-2)" "unprognostic (1.64e-1)" "prognostic unfavorable (3.21e-4)" "unprognostic (7.13e-2)" "unprognostic (3.82e-2)" "prognostic unfavorable (1.30e-4)" "unprognostic (2.73e-3)" "unprognostic (4.41e-1)" "unprognostic (5.79e-2)" "unprognostic (3.94e-3)" "unprognostic (3.77e-1)" "unprognostic (5.20e-3)" "unprognostic (5.15e-3)" "unprognostic (6.78e-2)" "unprognostic (1.03e-1)" "unprognostic (2.40e-1)" 11.3 13.8 12.6 21.1 16.1 24.0 16.8 8.1 16.3 18.5 10.8 25.9 26.1 14.6 7.7 51.8 16.6 14.1 20.9 14.9 9.3 13.9 13.1 17.0 21.5 11.8 9.3 12.0 22.4 19.4 19.8 14.9 11.5 20.5 22.4 8.8 27.0 13.1 20.8 40.9 25.1 16.3 7.3 24.1 20.9 10.6 9.5 23.2 19.5 13.7 24.0 19.3 25.0 17.9 52.0 34.1 26.6 28.6 14.6 18.6 35.2 20.8 20.0 29.5 22.3 34.1 49.5 37.8 35.6 20.8 32.0 57.5 26.9 28.7 24.6 26.7 20.9 40.7 23.9 20.3 17.0 45.9 51.4 10.9 36.8 27.0 21.4 13.5 24.7 33.6 35.7 36.5 19.5 64.4 49.3 29.9 31.7 36.0 24.2 39.9 20.4 39.7 19.1 39.8 37.9 25.4 34.7 90.2 24.3 28.9 65.1 26.4 22.7 30.3 19.1 39.6 23.4 24.5 28.8 36.7 20.1 23.2 25.3 1.4 0.7 2.1 1.3 0.7 2.1 0.9 1.0 1.3 1.0 1.6 0.8 0.9 3.6 1.6 1.1 0.9 0.6 0.7 12.6 16.1 8.1 16.3 14.9 9.3 11.8 9.3 11.5 7.3 9.5 17.9 17.3 6.4 6.8 29.7 18.5 25.2 21.1 9.1 19.4 26.8 30.0 18.2 12.8 27.1 11.9 20.2 8.4 26.0 33.4 90.3 1.9 20.2 0.6 29.5 15.8 14.7 29.9 14.7 43.6 21.4 20.6 11.7 27.0 41.0 17.2 21.1 13.6 13.0 17.9 20.2 30.3 39.9 10.2 26.7 18.5 0.9 12.8 25.0 3.6 29.0 17.0 18.8 36.0 31.7 51.8 27.3 39.4 10.9 15.6 30.4 33.4 8.1 14.5 18.1 19.7 19.6 13.1 9.1 18.4 39.9 34.4 65.0 23.6 16.0 33.6 44.3 MARVELD2 "DFNB49, FLJ30532, MRVLDC2, TRIC" ENSG00000152939 "MARVEL domain containing 2" Q8N4S9 5 69415065-69444330 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Hearing "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 15.7" "Cell type enhanced" "Detected in many" "Urothelial cells: 46.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 29.5;CAPAN-2: 24.1;HaCaT: 18.9;RT4: 21.1;SCLC-21H: 26.7;T-47d: 18.3" "Region enriched" "Detected in some" 8 "cerebellum: 7.9" "Low region specificity" "Detected in all" "HPA018119, HPA061726" Uncertain Supported "Cell Junctions" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 22: Epithelial cell types - Mixed function" "Cell Junctions" "HPA018119: AB_2669771, HPA061726: AB_2684595" "unprognostic (4.11e-2)" "unprognostic (3.05e-1)" "unprognostic (1.22e-2)" "unprognostic (2.44e-3)" "unprognostic (1.68e-1)" "unprognostic (1.17e-1)" "unprognostic (2.49e-1)" "unprognostic (8.84e-2)" "unprognostic (2.43e-1)" "unprognostic (3.47e-2)" "unprognostic (2.60e-2)" "unprognostic (1.75e-1)" "prognostic favorable (2.84e-13)" "unprognostic (1.78e-1)" "unprognostic (1.19e-1)" "unprognostic (3.67e-2)" "unprognostic (1.82e-1)" 0.3 0.2 0.5 0.9 0.5 0.2 4.0 0.5 0.6 2.1 3.2 5.7 7.7 1.1 1.3 6.9 3.9 2.9 0.4 0.5 0.5 8.0 10.7 5.6 0.1 0.7 0.7 0.1 9.3 4.6 2.9 1.8 0.7 3.0 6.2 0.3 4.6 2.6 0.0 4.3 7.7 0.4 0.4 0.2 8.1 1.5 0.7 1.0 15.7 0.0 1.3 3.0 3.4 0.7 10.8 3.5 0.1 0.0 0.0 0.0 29.5 0.2 0.2 0.2 0.7 14.1 24.1 0.1 2.0 1.8 0.0 18.9 0.0 14.0 0.5 0.2 5.8 0.0 1.1 7.8 1.7 0.0 0.1 0.4 15.3 0.1 1.9 0.7 0.9 0.1 0.0 0.1 0.0 9.8 0.0 0.0 1.8 6.3 0.3 0.0 0.1 0.5 10.0 21.1 26.7 0.0 2.3 2.0 0.3 4.3 18.3 0.0 1.5 0.0 0.1 0.0 0.0 0.1 3.5 0.0 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.2 0.3 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.5 0.5 0.5 0.6 0.5 0.5 0.7 0.7 0.7 0.4 0.7 0.7 1.0 22.4 26.5 0.7 1.0 5.0 22.2 14.8 10.2 0.3 15.5 8.5 2.8 35.8 23.1 16.5 2.1 22.9 0.2 31.4 17.6 25.1 5.8 33.5 3.4 4.1 16.8 3.4 0.5 25.8 8.2 1.1 17.9 30.4 1.3 3.7 5.0 37.9 1.9 0.0 0.4 23.1 18.3 0.6 0.9 3.2 0.0 0.6 1.8 1.0 7.8 0.5 0.0 0.5 0.6 25.0 29.7 0.0 0.6 25.5 33.5 6.1 38.4 0.6 0.0 0.8 1.5 4.1 2.4 19.4 6.5 12.0 0.9 2.9 25.6 46.9 MAST1 "KIAA0973, SAST" ENSG00000105613 "Microtubule associated serine/threonine kinase 1" Q9Y2H9 19 12833951-12874952 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 37.7;pituitary gland: 23.3;retina: 15.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 24.7;Cone photoreceptor cells: 43.8;Excitatory neurons: 64.7;Inhibitory neurons: 70.3;Oligodendrocyte precursor cells: 22.1;Rod photoreceptor cells: 20.4" "Cancer enhanced" "Detected in many" "glioma: 3.5" "Region enhanced" "Detected in many" "cerebral cortex: 37.7" "Immune cell enhanced" "Detected in single" "MAIT T-cell: 1.0" "Lineage enriched" "Detected in single" 9 "T-cells: 1.0" "Cell line enhanced" "Detected in many" "AN3-CA: 23.3;SCLC-21H: 40.5;SH-SY5Y: 20.2;U-266/70: 16.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028181, HPA073106" Enhanced Supported Vesicles,Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles Cytosol "HPA028181: AB_10603872, HPA073106: AB_2732218" "unprognostic (6.32e-2)" "unprognostic (3.66e-2)" "unprognostic (3.93e-2)" "unprognostic (2.83e-5)" "unprognostic (1.72e-1)" "unprognostic (4.19e-2)" "unprognostic (2.38e-1)" "unprognostic (8.72e-2)" "unprognostic (1.04e-1)" "unprognostic (3.64e-1)" "unprognostic (8.89e-3)" "unprognostic (3.43e-2)" "unprognostic (3.84e-3)" "unprognostic (1.19e-1)" "unprognostic (7.04e-2)" "unprognostic (2.49e-2)" "unprognostic (1.96e-1)" 0.0 2.2 6.5 0.3 12.1 0.3 0.1 7.3 37.7 0.2 0.0 1.2 0.3 0.0 0.0 0.2 0.1 0.2 0.2 8.3 2.4 0.1 0.6 0.1 0.1 11.2 1.1 0.3 0.6 0.5 23.3 0.0 9.5 0.2 0.1 15.4 0.2 0.0 0.0 3.7 0.4 0.0 0.0 0.1 0.6 5.0 1.2 0.8 0.1 0.0 0.0 0.2 0.3 3.0 3.6 1.6 1.5 23.3 0.0 0.0 1.9 0.2 0.1 0.3 0.9 0.8 1.5 5.8 2.6 0.0 3.9 0.1 6.8 0.1 0.1 4.1 4.5 0.5 5.8 2.6 0.0 1.3 1.2 0.5 0.1 0.8 0.7 1.3 0.0 15.2 5.2 3.0 0.0 0.8 2.4 0.6 6.9 0.6 7.2 15.9 4.6 8.3 0.3 0.2 40.5 20.2 0.8 1.4 4.3 1.2 3.8 2.1 0.0 2.8 4.2 3.1 0.8 16.7 14.5 3.7 5.1 3.1 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 6.5 12.1 7.3 37.7 8.3 2.4 11.2 1.1 9.5 0.0 1.2 3.0 0.5 0.0 2.4 7.8 0.2 0.9 1.6 0.6 0.6 24.7 0.8 2.5 1.0 0.0 0.3 0.0 43.8 0.6 0.4 0.6 0.0 0.4 14.0 0.2 0.2 1.3 0.0 0.0 64.7 0.5 0.6 1.3 0.0 0.3 1.3 0.5 1.1 0.5 0.2 15.2 70.3 0.1 0.0 1.0 1.2 8.2 0.6 0.7 5.4 6.5 0.1 3.7 0.0 22.1 3.0 0.3 2.5 1.2 0.0 1.0 0.9 0.2 1.0 20.4 0.0 2.0 0.5 8.0 5.2 0.7 1.4 0.3 1.0 0.4 0.7 1.2 MCF2 "ARHGEF21, DBL" ENSG00000101977 "MCF.2 cell line derived transforming sequence" P10911 X 139581770-139708227 "Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 29.5;seminal vesicle: 17.0;testis: 18.6" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 98.0;Excitatory neurons: 27.8;Inhibitory neurons: 36.2;Oligodendrocyte precursor cells: 20.6;Theca cells: 22.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 12 "U-251 MG: 37.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (2.42e-1)" "unprognostic (2.18e-2)" "unprognostic (1.46e-2)" "unprognostic (5.11e-4)" "unprognostic (8.95e-2)" "unprognostic (3.99e-2)" "unprognostic (1.24e-1)" "unprognostic (2.28e-1)" "unprognostic (1.80e-1)" "unprognostic (1.28e-1)" "unprognostic (2.63e-2)" "unprognostic (7.77e-2)" "unprognostic (2.33e-3)" "unprognostic (3.68e-2)" "unprognostic (2.92e-2)" "unprognostic (4.62e-4)" "unprognostic (4.02e-2)" 0.2 29.5 5.8 0.4 4.5 0.7 0.1 6.4 8.8 0.0 1.7 0.1 0.0 0.1 12.3 0.0 0.8 0.7 1.0 4.4 7.0 1.5 0.2 0.1 0.6 9.1 7.4 10.2 0.2 0.0 3.4 0.0 9.7 1.2 0.0 9.2 1.0 17.0 0.1 0.1 0.3 0.0 5.5 1.1 0.2 18.6 14.1 0.5 1.1 0.2 0.1 0.2 0.1 5.9 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.1 0.3 0.0 0.0 0.0 1.6 0.0 0.2 0.0 0.2 0.0 0.0 0.2 0.0 0.5 3.1 0.0 0.5 0.6 2.5 0.0 0.0 0.1 1.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.3 0.6 37.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.8 4.5 6.4 8.8 4.4 7.0 9.1 7.4 9.7 5.5 14.1 5.9 0.2 0.0 0.0 3.6 0.3 0.1 0.3 0.2 0.6 2.2 0.6 0.4 1.8 0.0 0.0 0.0 98.0 0.0 0.3 0.1 0.0 0.0 1.0 0.1 0.1 0.1 0.0 0.0 27.8 0.0 0.0 0.7 0.0 0.1 0.0 2.2 0.4 0.2 0.1 0.0 36.2 0.0 0.0 0.6 0.3 2.5 1.2 0.2 0.0 4.7 1.4 1.0 4.1 20.6 7.6 0.1 0.0 8.2 0.1 0.4 0.0 0.6 0.0 2.4 0.0 0.1 0.4 0.6 0.8 0.1 0.0 0.0 0.3 22.8 0.0 0.2 MCTP1 FLJ22344 ENSG00000175471 "Multiple C2 and transmembrane domain containing 1" Q6DN14 5 94703741-95284575 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 45.3;brain: 37.1" "Cell type enhanced" "Detected in many" "Adipocytes: 113.3;Excitatory neurons: 510.6;Inhibitory neurons: 412.2;Oligodendrocyte precursor cells: 263.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 46 "basophil: 37.0;classical monocyte: 28.6;eosinophil: 13.2;intermediate monocyte: 41.4;myeloid DC: 22.3;neutrophil: 40.5;non-classical monocyte: 40.6;plasmacytoid DC: 11.4" "Group enriched" "Detected in many" 54 "dendritic cells: 22.3;granulocytes: 40.5;monocytes: 41.4" "Cell line enhanced" "Detected in many" "Karpas-707: 71.4;RPMI-8226: 73.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019018 Approved Nucleoplasm,Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 25: RPMI-8226 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Cytosol" "HPA019018: AB_1853665" "unprognostic (1.20e-2)" "unprognostic (6.70e-4)" "unprognostic (1.77e-2)" "unprognostic (1.03e-2)" "unprognostic (1.16e-4)" "unprognostic (1.88e-1)" "unprognostic (1.16e-2)" "unprognostic (2.47e-2)" "unprognostic (1.86e-1)" "unprognostic (6.99e-2)" "unprognostic (5.31e-2)" "unprognostic (1.35e-1)" "unprognostic (1.91e-6)" "unprognostic (5.38e-2)" "unprognostic (3.65e-2)" "unprognostic (2.89e-3)" "unprognostic (4.43e-2)" 21.3 2.3 12.8 12.5 37.1 45.3 15.9 27.7 19.4 6.0 0.0 7.7 5.1 5.9 2.0 6.4 4.9 17.4 3.8 20.9 10.0 4.4 3.7 12.9 6.1 3.8 0.5 1.7 3.2 1.9 4.0 7.3 5.7 3.5 7.2 1.7 3.7 2.2 3.2 4.3 4.9 11.2 0.5 8.8 5.5 2.1 1.4 7.9 4.6 7.9 4.4 21.3 6.1 13.4 0.3 5.2 3.3 0.1 49.0 19.6 0.2 0.3 25.1 2.3 8.1 0.1 13.3 18.7 19.2 0.0 51.1 0.2 0.4 0.2 2.8 0.0 3.6 11.4 13.3 0.2 6.4 23.6 14.6 7.3 0.0 9.0 32.5 21.2 52.7 7.6 0.3 71.4 18.7 0.6 1.4 17.9 4.1 0.3 20.7 0.9 0.2 73.7 52.7 29.0 10.0 0.5 1.7 0.1 37.1 1.4 0.0 21.8 0.3 9.0 13.9 0.4 4.2 5.0 0.1 0.2 41.8 38.5 9.1 37.0 28.6 13.2 0.1 41.4 0.0 0.6 0.1 0.2 22.3 0.3 0.4 0.0 40.5 0.3 40.6 11.4 0.0 8.5 12.8 37.1 27.7 19.4 20.9 10.0 3.8 0.5 5.7 0.5 1.4 13.4 113.3 3.2 10.8 15.3 3.2 18.1 0.2 6.9 3.4 2.2 1.7 1.1 3.1 0.0 6.6 3.7 0.0 0.3 9.8 0.1 0.0 0.0 27.8 5.5 1.2 97.9 0.0 5.0 510.6 0.2 0.2 18.5 5.6 11.6 63.3 0.1 2.2 0.3 12.2 3.3 412.2 0.0 4.1 42.4 76.5 16.2 0.6 63.5 12.4 67.5 32.9 3.2 2.1 263.4 9.0 1.3 0.0 0.0 2.4 0.8 0.0 0.5 3.5 3.5 0.0 1.8 2.0 1.8 1.4 0.7 13.4 0.3 3.7 0.3 0.0 0.6 MECR "CGI-63, ETR1, FASN2B, NRBF1" ENSG00000116353 "Mitochondrial trans-2-enoyl-CoA reductase" Q9BV79 1 29192657-29230942 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Disease variant, Dystonia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 42.1" "Cell type enhanced" "Detected in all" "Late spermatids: 82.5;Rod photoreceptor cells: 68.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022018, HPA022030, HPA028740" Enhanced Supported Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 25: RPMI-8226 - Immune response" "Cluster 46: Photoreceptor cells - Phototransduction" Mitochondria "HPA022018: AB_1853714, HPA022030: AB_1853716, HPA028740: AB_10601133" "unprognostic (2.53e-1)" "unprognostic (1.09e-2)" "unprognostic (1.52e-1)" "unprognostic (1.84e-1)" "unprognostic (1.07e-1)" "unprognostic (2.46e-1)" "unprognostic (1.39e-1)" "unprognostic (2.07e-1)" "unprognostic (1.34e-1)" "unprognostic (1.69e-1)" "unprognostic (3.06e-2)" "unprognostic (8.66e-2)" "prognostic favorable (5.81e-6)" "unprognostic (7.01e-3)" "unprognostic (3.29e-2)" "unprognostic (2.59e-1)" "prognostic unfavorable (5.29e-4)" 14.7 14.6 5.1 1.7 5.1 1.8 13.4 3.3 6.2 10.2 3.1 10.3 1.4 12.9 2.5 12.5 9.4 1.3 24.8 6.0 3.9 14.1 15.8 7.3 2.0 5.2 4.0 10.0 8.9 4.5 7.2 3.5 5.4 7.9 2.6 9.9 12.3 3.0 42.1 15.4 7.2 3.1 3.2 6.7 11.1 7.6 4.3 1.4 8.3 5.8 2.1 9.6 9.6 5.2 3.9 4.5 3.2 4.6 2.9 2.5 6.8 3.7 3.8 4.7 3.9 2.3 5.6 7.3 5.1 3.7 1.3 3.0 5.4 6.3 4.0 4.4 6.9 6.4 3.4 4.1 6.6 6.1 1.9 4.3 5.9 3.1 11.0 3.8 3.5 6.9 5.8 4.2 4.7 4.5 3.9 2.9 6.5 5.8 4.3 3.5 4.2 9.3 5.9 2.4 5.1 4.5 4.1 4.7 7.0 4.4 2.3 5.4 3.8 2.4 2.9 4.1 4.7 2.7 2.2 5.0 3.9 8.4 5.2 0.1 2.2 0.0 1.5 2.1 4.1 2.2 1.6 1.7 1.9 1.1 2.3 1.6 0.3 2.9 1.6 2.5 2.4 1.2 5.1 5.1 3.3 6.2 6.0 3.9 5.2 4.0 5.4 3.2 4.3 5.2 8.8 12.8 3.9 14.7 9.1 5.6 15.6 26.9 7.4 12.8 12.0 14.6 19.8 21.5 21.4 20.2 10.4 46.0 3.8 7.4 41.1 24.3 40.8 19.7 13.6 9.1 7.8 10.1 25.1 19.7 42.4 12.8 4.6 12.8 5.7 17.5 7.1 19.7 20.8 8.4 20.3 9.4 12.2 6.0 5.1 82.5 13.7 5.3 16.0 3.7 10.8 14.5 10.3 11.6 15.2 16.3 8.0 10.9 10.3 20.6 10.9 46.0 11.3 68.5 13.1 13.2 12.9 8.5 16.1 14.0 7.4 27.9 6.0 25.8 18.3 20.5 MED26 "CRSP7, CRSP70" ENSG00000105085 "Mediator complex subunit 26" O95402 19 16574907-16629062 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 35.9" "Cell type enhanced" "Detected in many" "Early spermatids: 65.4;Late spermatids: 67.4;Spermatocytes: 54.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057997, HPA071835" Enhanced Approved Nucleoplasm,Vesicles,Cytosol Yes No "Cluster 46: Basophils - DNA binding" "Cluster 23: Testis - Cell cycle regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "Vesicles, Cytosol" "HPA057997: AB_2732618, HPA071835: AB_2686455" "unprognostic (2.02e-2)" "prognostic favorable (2.46e-4)" "unprognostic (2.47e-2)" "unprognostic (2.57e-3)" "unprognostic (1.42e-1)" "unprognostic (3.60e-3)" "unprognostic (5.03e-2)" "unprognostic (3.77e-2)" "unprognostic (1.34e-2)" "unprognostic (1.17e-2)" "unprognostic (2.99e-3)" "unprognostic (2.60e-2)" "prognostic unfavorable (5.50e-5)" "unprognostic (9.43e-3)" "unprognostic (1.64e-1)" "unprognostic (5.14e-2)" "unprognostic (5.98e-3)" 4.5 3.8 4.4 3.8 4.0 11.0 4.1 5.1 4.7 4.0 4.0 4.1 2.4 4.3 1.8 5.2 3.2 2.3 3.2 5.0 5.1 2.8 3.7 4.0 4.9 5.2 4.7 4.7 3.9 3.5 3.6 3.2 4.7 4.2 1.9 2.0 4.5 2.4 6.9 6.4 3.6 2.5 3.6 4.7 3.6 35.9 4.5 4.4 3.1 3.2 4.6 3.9 4.6 4.2 11.1 4.2 3.8 8.3 4.8 3.8 11.1 6.3 4.4 6.7 6.0 6.3 6.5 17.6 6.5 4.0 2.1 8.2 5.9 6.3 4.6 13.0 12.2 6.9 4.2 5.1 4.7 7.9 6.3 4.6 6.1 5.7 5.9 4.0 3.6 9.1 11.5 20.7 4.2 11.1 8.4 7.4 9.0 5.2 13.4 8.7 5.8 19.3 4.0 4.3 10.0 5.4 5.5 5.3 6.4 2.7 3.9 10.3 4.5 8.5 6.8 10.4 8.5 14.3 12.6 14.4 6.0 10.4 5.0 0.7 0.1 0.1 0.5 0.3 0.1 0.4 0.0 0.2 0.2 0.7 0.3 0.0 0.3 0.4 0.1 1.4 0.7 0.1 4.4 4.0 5.1 4.7 5.0 5.1 5.2 4.7 4.7 3.6 4.5 4.2 13.7 3.2 12.7 11.4 11.8 14.1 5.0 3.8 11.4 4.2 14.3 12.2 1.1 2.8 3.0 5.5 10.4 6.2 15.8 5.9 3.9 4.4 65.4 12.9 7.7 6.1 2.4 5.0 8.6 4.0 11.1 7.0 5.6 16.6 1.3 5.8 4.2 5.6 5.0 5.0 7.6 4.7 2.0 8.5 10.7 67.4 6.5 9.9 1.8 1.9 4.9 6.0 4.1 7.1 8.5 6.0 3.0 3.8 15.9 6.7 3.6 2.0 3.5 6.4 0.0 17.7 8.0 54.1 19.4 11.5 10.7 16.8 11.0 6.1 5.1 8.7 MEGF10 "KIAA1780, SR-F3" ENSG00000145794 "Multiple EGF like domains 10" Q96KG7 5 127290796-127465737 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Myogenesis, Phagocytosis" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 52.6" "Cell type enhanced" "Detected in some" "Astrocytes: 218.4;Oligodendrocyte precursor cells: 97.5;Oligodendrocytes: 381.7;Skeletal myocytes: 62.9" "Cancer enhanced" "Detected in some" "glioma: 3.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "AF22: 31.6;RH-30: 38.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA 73000000 "Cluster 70: Brain - Nervous system development" "Cluster 12: NES - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "unprognostic (7.02e-2)" "unprognostic (4.50e-2)" "unprognostic (1.02e-1)" "unprognostic (2.26e-3)" "unprognostic (8.91e-3)" "unprognostic (1.59e-2)" "unprognostic (1.35e-1)" "unprognostic (1.16e-1)" "unprognostic (1.99e-1)" "unprognostic (2.13e-1)" "unprognostic (1.52e-1)" "unprognostic (1.41e-1)" "unprognostic (1.76e-4)" "unprognostic (5.28e-3)" "unprognostic (2.59e-1)" "unprognostic (9.36e-4)" "unprognostic (1.17e-1)" 0.2 1.7 18.0 0.1 34.9 0.0 0.7 29.4 19.9 0.3 0.0 0.8 0.1 0.7 0.4 0.1 0.1 0.0 0.4 15.6 18.2 0.0 0.4 0.0 0.0 26.6 26.8 0.1 0.0 0.0 1.7 0.1 29.4 0.7 0.2 8.0 1.9 1.1 3.0 0.3 0.2 0.3 21.2 0.1 0.1 0.4 23.8 0.6 0.1 4.8 0.2 0.0 0.1 52.6 0.0 0.0 31.6 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 6.8 0.0 0.2 0.2 0.0 0.0 0.0 2.5 0.0 0.0 0.0 3.4 0.0 0.0 0.0 38.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.7 0.0 0.1 0.0 0.0 2.0 0.0 0.1 0.0 0.0 0.0 1.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.0 34.9 29.4 19.9 15.6 18.2 26.6 26.8 29.4 21.2 23.8 52.6 0.0 0.0 0.0 218.4 0.0 0.0 0.1 0.0 0.0 2.0 0.7 1.5 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 6.5 1.3 0.2 0.0 0.0 4.5 0.0 0.0 0.4 0.0 15.4 0.0 0.7 0.0 0.2 0.0 8.4 3.5 0.0 0.0 0.3 0.0 1.0 0.0 0.1 0.0 29.0 0.0 38.9 1.0 97.5 381.7 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 2.0 0.0 62.9 0.2 0.4 0.7 0.0 0.1 0.0 0.1 5.1 0.0 0.1 MFSD2A "FLJ14490, MFSD2" ENSG00000168389 "Major facilitator superfamily domain containing 2A" Q8NA29 1 39955112-39969968 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid transport, Symport, Transport" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 96.9;liver: 162.0;skin 1: 87.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 136.2;Hepatocytes: 299.6;Proximal enterocytes: 235.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "classical monocyte: 13.2;intermediate monocyte: 6.6;myeloid DC: 14.7;plasmacytoid DC: 24.3" "Group enriched" "Detected in many" 12 "dendritic cells: 24.3;monocytes: 13.2" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 52.0;THP-1: 169.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043107 Uncertain Approved "Plasma membrane,Cytosol,Cytoplasmic bodies" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 43: THP-1 - Innate immune response" "Cluster 2: Hepatocytes - Metabolism" Cytosol "Plasma membrane, Cytoplasmic bodies" "HPA043107: AB_10794387" "unprognostic (2.20e-1)" "unprognostic (1.15e-1)" "unprognostic (5.23e-3)" "unprognostic (1.06e-1)" "unprognostic (1.30e-1)" "unprognostic (6.92e-2)" "unprognostic (2.61e-2)" "unprognostic (2.45e-2)" "unprognostic (1.60e-1)" "unprognostic (4.33e-1)" "unprognostic (2.85e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (4.22e-6)" "unprognostic (9.26e-2)" "unprognostic (4.11e-1)" "unprognostic (1.09e-1)" "prognostic favorable (2.33e-4)" 6.3 1.4 34.0 3.4 31.7 8.4 13.4 34.8 36.0 4.8 22.2 7.2 14.6 8.5 96.9 12.5 3.5 2.3 1.4 30.9 33.4 5.8 162.0 36.1 2.3 38.5 33.8 2.2 0.6 0.7 8.0 17.1 38.6 2.4 5.0 2.6 4.0 79.2 0.5 87.8 32.0 3.5 32.8 1.5 1.9 33.9 37.2 1.6 7.5 0.1 3.6 20.2 14.1 33.1 6.2 2.7 12.5 18.9 8.7 1.6 0.0 5.9 11.2 12.8 15.1 0.8 3.4 38.0 3.4 3.0 8.8 15.0 12.4 21.8 9.8 4.9 6.0 4.6 0.1 0.1 28.8 6.8 21.8 9.7 13.3 52.0 21.5 2.3 3.1 11.5 0.0 9.5 5.7 0.8 10.6 10.4 10.1 21.4 4.7 7.4 18.5 8.7 2.1 17.9 4.4 6.7 4.5 31.7 3.0 1.1 1.5 169.8 2.0 2.7 5.3 9.5 24.9 1.8 3.5 8.5 28.9 26.0 9.2 0.0 13.2 1.4 0.1 6.6 0.2 1.5 0.1 0.2 14.7 0.2 0.0 0.1 0.7 0.2 1.2 24.3 0.0 3.6 34.0 31.7 34.8 36.0 30.9 33.4 38.5 33.8 38.6 32.8 37.2 33.1 0.5 19.2 136.2 3.3 6.3 52.8 21.2 40.0 51.2 2.0 6.3 2.3 0.6 12.8 30.8 16.5 0.0 0.5 5.7 62.2 0.0 3.4 1.0 25.8 5.5 22.9 1.2 5.7 1.5 24.8 7.6 9.7 24.5 61.8 17.2 0.1 7.1 299.6 6.7 0.0 1.3 34.5 12.2 9.8 43.3 2.7 0.6 16.1 0.0 38.4 5.5 38.8 0.0 0.0 1.6 27.2 39.3 0.4 5.0 13.9 235.1 6.1 33.9 2.7 0.0 5.0 3.3 1.0 1.3 49.3 54.8 52.5 3.3 0.1 20.7 26.6 MFSD4A "DKFZp761N1114, FLJ25004, FLJ34577, MFSD4, UNQ3064" ENSG00000174514 "Major facilitator superfamily domain containing 4A" Q8N468 1 205568885-205602918 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 66.7;stomach 1: 132.6" "Cell type enhanced" "Detected in some" "Adipocytes: 11.3;Collecting duct cells: 9.2;Distal tubular cells: 13.7;Endometrial ciliated cells: 9.9;Glandular and luminal cells: 40.5;Proximal tubular cells: 7.7" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 17 "amygdala: 11.4;basal ganglia: 8.4;cerebral cortex: 18.4;hippocampal formation: 14.1;white matter: 5.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 1.5;SCLC-21H: 1.6" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebral cortex: 59.8" HPA055407 Approved NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 44: Endometrium - Transcription" "HPA055407: " "unprognostic (7.15e-4)" "prognostic favorable (7.54e-4)" "unprognostic (5.60e-2)" "unprognostic (1.38e-1)" "unprognostic (2.09e-1)" "unprognostic (1.56e-2)" "unprognostic (1.25e-1)" "prognostic favorable (4.59e-4)" "unprognostic (2.73e-2)" "unprognostic (1.65e-2)" "unprognostic (3.20e-2)" "unprognostic (6.97e-3)" "prognostic favorable (2.27e-13)" "unprognostic (1.58e-1)" "unprognostic (4.44e-2)" "unprognostic (5.75e-3)" "unprognostic (8.78e-2)" 2.2 0.4 11.4 1.1 8.4 0.0 2.7 0.6 18.4 8.5 0.0 13.8 1.9 1.0 9.2 1.4 2.5 16.8 0.9 14.1 0.0 66.7 0.2 6.8 0.4 0.0 0.0 0.6 1.4 0.4 1.5 6.2 0.0 1.4 18.2 14.0 17.1 0.6 0.3 5.1 1.4 0.8 0.0 0.6 132.6 0.5 0.0 0.6 0.4 0.7 1.3 0.7 0.8 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.7 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 1.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 8.4 0.6 18.4 14.1 0.0 0.0 0.0 0.0 0.0 0.0 5.3 11.3 6.4 2.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 3.8 2.9 0.0 0.0 6.2 9.2 0.0 0.5 0.7 0.0 13.7 1.4 0.0 9.9 6.0 2.5 0.0 0.0 0.0 6.2 0.1 0.5 0.0 40.5 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 7.7 2.9 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.8 0.2 0.0 0.0 MGME1 "bA504H3.4, C20orf72, DDK1" ENSG00000125871 "Mitochondrial genome maintenance exonuclease 1" Q9BQP7 20 17969018-17991122 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "Exonuclease, Hydrolase, Nuclease" "Disease variant, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040913 Approved Supported Mitochondria NA Yes "Cluster 2: Granulocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 6: Erythroid cells - Oxygen transport" Mitochondria "HPA040913: AB_10962835" "unprognostic (5.81e-3)" "unprognostic (5.96e-2)" "unprognostic (1.28e-1)" "unprognostic (1.29e-3)" "unprognostic (5.42e-2)" "unprognostic (1.44e-2)" "prognostic unfavorable (6.98e-8)" "unprognostic (5.31e-2)" "unprognostic (7.05e-2)" "unprognostic (2.91e-2)" "unprognostic (1.06e-2)" "unprognostic (7.45e-2)" "prognostic unfavorable (1.13e-7)" "unprognostic (2.04e-1)" "unprognostic (3.22e-2)" "unprognostic (8.70e-2)" "unprognostic (6.89e-2)" 6.5 14.4 7.5 11.7 8.2 16.0 18.4 8.0 9.7 7.3 7.9 11.4 13.4 5.2 10.4 13.1 6.2 7.3 10.8 7.2 7.5 12.8 14.4 7.7 19.9 8.6 8.1 5.9 8.8 7.8 4.7 12.8 8.7 7.5 13.4 7.8 9.0 7.4 21.3 34.2 11.9 6.7 8.3 17.7 9.3 10.7 7.9 19.8 11.9 12.1 20.8 8.9 9.5 9.3 44.7 51.0 41.0 38.7 16.5 29.0 54.9 36.8 27.1 34.8 47.4 63.4 44.7 53.4 20.3 16.4 39.6 64.9 43.1 55.1 52.7 19.9 34.7 34.7 29.6 97.2 12.3 22.9 56.2 17.6 37.3 52.3 27.4 16.3 28.2 26.0 48.0 33.3 70.7 33.4 40.5 29.9 36.3 26.8 44.0 30.5 91.4 50.8 30.1 32.3 31.6 26.1 26.1 62.8 57.7 33.2 59.7 15.5 22.8 59.1 48.1 29.8 40.3 24.6 59.6 45.3 15.2 17.3 44.7 57.5 15.2 44.6 8.1 14.9 10.9 21.0 10.5 10.9 12.6 24.2 7.5 6.9 14.4 16.7 15.0 19.5 17.1 8.4 7.5 8.2 8.0 9.7 7.2 7.5 8.6 8.1 8.7 8.3 7.9 9.3 10.6 0.0 10.0 19.9 24.6 46.4 15.7 12.7 40.9 7.9 19.9 39.4 12.6 15.7 11.9 7.3 8.4 22.9 21.0 14.3 39.2 13.1 9.8 11.2 15.6 11.9 7.2 52.6 3.1 10.2 25.9 8.1 5.1 13.3 48.0 25.5 20.0 9.9 31.4 8.4 2.9 12.1 6.1 34.4 15.4 5.5 8.4 18.8 21.4 9.4 16.4 11.4 28.8 17.6 12.6 10.4 10.6 5.7 13.2 12.3 31.0 26.5 5.9 10.0 13.1 10.3 10.8 38.6 47.0 20.5 46.9 18.1 14.9 27.1 19.0 12.8 MGST1 "GST12, MGST-I" ENSG00000008394 "Microsomal glutathione S-transferase 1" P10620 12 16347142-16609259 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 1096.9;adrenal gland: 1137.3;liver: 3104.7" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 1205.9;Club cells: 1308.7;Hepatocytes: 4345.6;Proximal tubular cells: 1265.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 170.2;myeloid DC: 123.5" "Group enriched" "Detected in many" 13 "dendritic cells: 123.5;monocytes: 170.2" "Cell line enhanced" "Detected in many" "ASC diff: 5391.4;ASC TERT1: 2078.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044840 Enhanced Approved "Endoplasmic reticulum,Mitochondria" NA NA 19000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Mitochondria "Endoplasmic reticulum" "HPA044840: AB_10965550" "unprognostic (4.57e-2)" "unprognostic (4.80e-3)" "unprognostic (5.82e-2)" "unprognostic (2.92e-3)" "unprognostic (3.97e-3)" "unprognostic (1.03e-1)" "unprognostic (8.19e-2)" "unprognostic (1.03e-1)" "unprognostic (4.82e-2)" "unprognostic (3.42e-1)" "unprognostic (1.37e-3)" "unprognostic (2.20e-1)" "prognostic unfavorable (7.45e-4)" "unprognostic (9.90e-2)" "unprognostic (4.61e-1)" "prognostic favorable (1.97e-4)" "unprognostic (4.19e-1)" 1096.9 1137.3 139.2 76.1 143.9 79.3 574.8 131.4 200.7 69.7 111.9 315.5 128.9 32.7 43.9 195.3 78.4 200.8 135.1 133.9 165.4 392.9 3104.7 177.2 3.5 156.5 155.7 11.4 131.3 0.8 52.6 14.2 166.6 161.2 212.8 7.0 155.3 55.8 25.5 88.8 119.5 44.7 146.4 7.3 131.4 20.2 147.5 14.0 272.3 43.3 7.7 267.9 114.7 132.9 1.4 495.2 115.6 139.4 5391.4 2078.4 1.5 408.5 418.5 220.6 339.1 186.0 838.6 0.4 48.5 535.8 694.2 2.4 317.0 663.5 202.9 1.1 41.4 175.7 256.6 664.8 1252.0 350.4 1.2 1375.9 714.7 671.2 710.5 540.4 393.1 0.1 126.7 0.6 486.3 101.2 0.3 137.0 987.6 0.7 391.2 0.4 69.3 229.3 503.3 982.1 21.8 17.1 645.8 411.8 17.5 630.1 442.5 190.8 248.0 226.1 30.5 447.3 541.1 0.6 1.7 1.5 748.1 538.5 7.1 11.3 170.2 1.8 0.1 26.3 0.5 1.0 0.2 0.1 123.5 0.0 0.1 0.1 5.9 0.2 5.9 34.1 1.1 55.9 139.2 143.9 131.4 200.7 133.9 165.4 156.5 155.7 166.6 146.4 147.5 132.9 39.6 266.0 651.3 130.2 14.0 25.6 130.2 1205.9 91.0 0.0 383.8 262.6 5.1 574.7 1308.7 71.7 0.0 2.9 9.8 288.1 181.9 26.9 25.4 299.9 198.2 19.6 45.6 92.8 4.4 434.1 218.1 404.5 153.9 947.9 34.1 26.3 67.5 4345.6 160.2 0.0 0.5 280.5 740.6 176.4 52.0 17.9 33.2 75.7 39.2 6.5 224.4 1.0 5.2 1.0 0.8 322.7 175.0 113.2 6.0 467.2 209.5 1265.6 526.1 1.3 0.0 11.3 124.3 0.7 2.3 510.3 17.6 7.9 22.1 152.4 534.1 883.3 MID1IP1 "FLJ10386, G12-like, MIG12, STRAIT11499, THRSPL" ENSG00000165175 "MID1 interacting protein 1" Q9NPA3 X 38801432-38806537 "Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 150.2" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 217.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 15.7" "Lineage enriched" "Detected in many" 8 "granulocytes: 15.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038816 Uncertain NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "HPA038816: AB_10670908" "unprognostic (5.35e-2)" "unprognostic (1.75e-1)" "unprognostic (1.24e-1)" "unprognostic (2.51e-2)" "unprognostic (1.07e-1)" "unprognostic (8.08e-2)" "prognostic unfavorable (2.20e-4)" "unprognostic (2.62e-2)" "unprognostic (3.10e-1)" "unprognostic (1.26e-2)" "unprognostic (2.88e-1)" "unprognostic (2.31e-3)" "prognostic favorable (1.15e-4)" "unprognostic (1.55e-1)" "unprognostic (1.29e-1)" "unprognostic (1.18e-2)" "prognostic favorable (8.06e-4)" 40.2 34.1 102.1 13.9 143.4 103.6 34.5 106.6 105.3 20.4 50.4 45.0 17.0 18.3 6.9 35.5 30.9 7.5 39.5 78.6 91.9 29.5 56.1 43.7 11.1 115.4 123.4 33.4 78.7 4.0 15.4 8.7 107.4 23.0 5.0 3.4 25.0 13.3 150.2 28.7 25.1 9.3 99.2 12.3 49.7 23.0 127.8 9.1 13.8 25.9 6.2 35.5 24.3 139.5 60.3 55.2 14.3 10.9 67.9 31.8 15.4 33.2 23.2 7.1 13.5 18.5 44.3 57.7 28.4 10.7 6.0 55.3 47.7 39.4 4.7 39.9 18.7 49.4 48.7 14.9 51.6 23.1 36.7 46.4 31.1 27.7 24.2 19.1 7.2 68.9 46.5 60.7 10.1 50.4 40.8 64.3 49.5 17.6 95.9 111.2 17.6 116.4 18.5 29.8 34.0 41.3 17.6 34.0 90.9 28.2 28.0 70.5 10.0 20.2 22.4 25.5 24.6 155.5 65.0 53.6 61.1 37.4 22.3 3.8 1.9 15.7 0.9 1.3 1.0 0.5 1.4 1.0 1.3 0.7 1.2 1.2 8.0 0.8 2.0 1.3 0.5 0.9 102.1 143.4 106.6 105.3 78.6 91.9 115.4 123.4 107.4 99.2 127.8 139.5 20.3 80.1 217.9 11.4 17.4 23.7 48.5 63.0 44.3 12.5 22.4 21.1 40.5 52.9 28.2 20.2 4.2 3.7 16.6 23.3 37.2 36.7 8.3 65.6 25.0 25.3 25.8 54.1 1.7 70.0 20.2 57.7 49.5 20.8 48.8 13.2 24.3 40.5 40.4 15.2 2.7 33.2 63.1 53.2 73.8 12.7 39.4 60.5 26.6 5.6 130.4 20.7 8.2 3.5 47.6 67.0 24.4 49.7 6.9 36.7 18.1 47.9 48.0 12.4 39.5 42.7 52.8 2.4 3.7 63.0 16.3 4.9 35.4 16.3 25.5 116.9 MISP3 ENSG00000141854 "MISP family member 3" Q96FF7 19 14072536-14075062 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 17.7" "Cell type enhanced" "Detected in some" "Breast glandular cells: 19.3;Breast myoepithelial cells: 20.8;Collecting duct cells: 14.7;Distal tubular cells: 35.2;Endometrial ciliated cells: 12.4;Exocrine glandular cells: 11.5;Proximal tubular cells: 22.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 5.3;OE19: 11.3;RPMI-8226: 6.3;U-266/84: 4.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA042225 Uncertain NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 22: Non-specific - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 35: Glandular cells - Unknown function" "HPA042225: AB_10795396" "unprognostic (1.69e-1)" "unprognostic (1.08e-1)" "unprognostic (1.39e-1)" "unprognostic (7.84e-2)" "unprognostic (1.30e-2)" "unprognostic (1.01e-2)" "unprognostic (3.66e-2)" "unprognostic (1.76e-3)" "unprognostic (9.77e-2)" "unprognostic (1.31e-2)" "unprognostic (8.81e-2)" "unprognostic (1.46e-1)" "prognostic favorable (9.52e-4)" "prognostic favorable (3.11e-5)" "unprognostic (2.97e-1)" "unprognostic (1.01e-1)" "unprognostic (9.78e-2)" 1.4 2.1 7.2 0.3 7.3 0.5 2.0 7.6 10.3 2.0 6.3 7.6 3.9 1.0 0.4 3.0 3.0 0.3 6.3 7.6 8.1 17.7 5.6 2.9 0.0 7.4 7.4 0.5 12.1 2.8 2.6 0.5 7.6 3.6 1.4 1.1 7.8 1.0 2.5 7.9 5.2 0.1 7.7 1.3 11.1 0.9 7.5 0.2 3.0 1.0 0.1 1.7 2.8 7.8 1.7 0.9 0.3 0.7 0.6 0.4 0.1 0.1 0.1 0.0 0.1 0.0 0.3 0.1 1.1 0.1 0.0 0.6 0.8 0.0 0.0 2.1 1.5 0.2 0.3 0.8 0.1 0.1 0.3 0.1 0.0 0.0 0.1 0.7 0.2 1.0 0.2 5.3 0.0 3.0 0.3 0.7 0.0 11.3 0.7 0.5 0.1 6.3 1.1 0.0 1.5 0.4 0.0 0.5 0.6 0.0 0.9 0.0 0.1 0.0 0.4 0.5 0.0 3.6 4.3 0.4 0.8 1.3 0.1 0.0 0.1 0.3 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.8 7.2 7.3 7.6 10.3 7.6 8.1 7.4 7.4 7.6 7.7 7.5 7.8 3.2 9.6 1.5 0.0 0.6 0.0 0.0 0.0 0.0 0.0 19.3 20.8 0.0 0.0 1.8 14.7 0.0 0.2 3.7 0.0 35.2 2.5 0.0 12.4 0.8 0.7 0.0 0.0 0.0 11.5 0.1 1.0 0.0 5.9 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 1.3 0.0 0.0 22.8 2.9 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 3.0 1.5 0.3 0.0 0.0 MOB2 HCCA2 ENSG00000182208 "MOB kinase activator 2" Q70IA6 11 1469457-1501247 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046313 Uncertain Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 80: Striated muscle - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoli "Nucleoplasm, Cytosol" "HPA046313: AB_10959882" "unprognostic (5.02e-1)" "unprognostic (5.71e-2)" "unprognostic (6.24e-3)" "unprognostic (4.42e-3)" "prognostic unfavorable (4.64e-4)" "unprognostic (8.30e-2)" "unprognostic (1.06e-3)" "unprognostic (3.06e-2)" "unprognostic (1.77e-1)" "unprognostic (2.80e-2)" "unprognostic (5.30e-2)" "unprognostic (2.87e-1)" "prognostic favorable (2.02e-4)" "unprognostic (2.67e-1)" "unprognostic (8.56e-2)" "unprognostic (9.78e-2)" "unprognostic (1.15e-1)" 32.3 19.6 34.7 19.2 36.3 24.2 28.3 37.8 39.7 27.4 36.2 61.1 18.0 30.7 36.5 51.9 34.4 27.8 43.5 35.3 36.5 18.6 20.0 24.7 26.8 36.1 36.8 28.1 32.8 34.9 11.2 25.7 36.5 32.5 34.8 14.6 35.2 42.3 50.9 50.0 28.6 49.0 36.1 25.1 27.9 14.2 37.1 34.1 24.2 70.4 27.0 39.9 31.6 37.8 29.3 31.2 18.3 15.7 44.2 30.8 17.1 22.5 30.9 40.4 31.8 20.1 39.0 20.9 16.7 50.6 26.0 34.8 28.1 48.6 24.3 28.8 44.3 16.0 11.7 26.2 30.2 21.2 24.2 25.1 57.9 21.9 25.3 32.7 43.6 27.0 26.3 21.2 20.7 20.6 27.4 37.7 23.0 54.3 29.4 19.9 19.0 22.2 34.4 26.9 34.6 37.3 27.3 34.0 27.9 23.0 15.9 21.3 37.7 25.6 13.1 8.3 14.5 21.6 22.3 21.8 17.9 20.3 19.8 9.7 8.7 11.9 16.2 9.2 13.6 8.1 14.1 13.7 10.6 11.0 11.6 10.2 7.1 12.1 13.4 7.5 15.3 10.6 34.7 36.3 37.8 39.7 35.3 36.5 36.1 36.8 36.5 36.1 37.1 37.8 84.8 6.4 10.0 6.5 20.2 82.2 30.1 39.4 12.0 18.4 27.8 33.3 14.8 12.8 18.4 7.3 12.5 31.1 64.5 58.6 27.4 33.5 24.3 18.9 17.7 58.2 20.9 36.2 15.2 38.5 31.0 23.3 16.8 29.2 24.8 20.3 33.9 9.0 26.4 43.7 10.9 32.8 32.6 18.2 39.3 12.1 23.9 28.1 56.9 11.2 29.4 21.5 81.4 6.6 14.8 39.6 63.2 51.1 17.0 48.6 54.3 23.9 12.9 21.4 85.5 20.8 68.3 29.8 41.1 13.7 82.0 59.4 36.4 20.2 27.7 37.6 MORN3 ENSG00000139714 "MORN repeat containing 3" Q6PF18 12 121648742-121672631 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 4.1;fallopian tube: 3.9;testis: 4.5" "Cell type enriched" "Detected in many" 6 "Late spermatids: 2271.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 9 "BEWO: 13.6;CACO-2: 8.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA038709, HPA038710" Uncertain Approved Nucleoplasm NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "HPA038709: AB_2676164, HPA038710: AB_2676165" "prognostic favorable (1.16e-4)" "unprognostic (2.70e-3)" "unprognostic (5.56e-2)" "unprognostic (5.13e-2)" "unprognostic (7.38e-3)" "unprognostic (3.46e-3)" "unprognostic (7.44e-2)" "unprognostic (3.70e-2)" "unprognostic (4.31e-2)" "unprognostic (3.09e-2)" "unprognostic (3.65e-3)" "unprognostic (3.11e-2)" "unprognostic (1.39e-2)" "unprognostic (3.06e-1)" "unprognostic (2.21e-1)" "unprognostic (8.85e-2)" "unprognostic (1.18e-1)" 0.2 0.3 1.4 0.5 1.6 0.9 0.4 1.3 1.6 0.4 4.1 0.2 0.2 0.3 0.5 0.1 3.9 0.4 0.2 1.5 1.5 0.7 0.1 1.0 1.2 1.7 2.2 0.3 0.3 2.3 1.3 0.8 1.1 0.2 0.2 0.6 0.4 0.3 0.2 2.0 0.4 0.2 1.3 0.7 0.6 4.5 1.6 0.9 0.6 0.0 0.6 0.2 0.2 1.4 0.2 0.1 0.4 0.2 0.0 0.3 13.6 0.2 0.1 0.0 0.1 8.3 0.4 0.2 0.2 0.1 0.2 0.5 0.1 0.2 0.1 0.1 0.1 0.6 0.5 0.5 0.2 0.5 0.9 0.1 0.3 0.4 0.0 0.1 0.3 1.0 0.2 0.3 0.1 0.3 0.9 0.7 0.3 0.0 0.1 0.4 0.0 0.1 0.5 0.2 1.2 1.1 0.1 0.2 0.0 0.6 1.1 0.1 0.2 0.2 0.2 0.4 0.2 0.2 0.1 0.4 1.0 0.4 0.2 1.3 0.3 0.1 0.7 0.1 0.8 0.3 0.8 0.4 0.1 0.5 0.7 0.5 1.2 0.9 0.3 0.5 0.8 0.2 1.4 1.6 1.3 1.6 1.5 1.5 1.7 2.2 1.1 1.3 1.6 1.4 1.1 3.2 1.3 0.0 1.6 3.2 1.2 3.3 0.0 1.3 2.5 1.8 1.4 4.3 8.2 1.8 0.0 0.5 6.6 0.0 7.9 4.4 352.0 34.1 1.2 2.1 0.0 0.0 2.7 1.4 0.7 1.4 0.0 3.0 2.5 2.5 0.7 0.0 0.9 0.0 2.3 0.0 4.1 0.0 0.3 2271.5 9.3 1.7 0.0 0.0 1.8 5.4 5.2 0.0 0.1 2.2 0.0 9.4 3.5 0.7 0.1 1.1 51.7 2.2 0.0 1.5 1.4 8.7 6.7 0.0 4.0 7.3 6.7 3.4 0.2 1.1 MPP7 FLJ32798 ENSG00000150054 "Membrane palmitoylated protein 7" Q5T2T1 10 28050993-28334486 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 37.1" "Cell type enhanced" "Detected in many" "Early spermatids: 82.3;Excitatory neurons: 76.7;Suprabasal keratinocytes: 61.1" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 4.7" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 23.3;CACO-2: 45.2;CAPAN-2: 27.9;T-47d: 89.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037597, HPA037598" Approved Supported "Nucleoplasm,Cell Junctions" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 6: T47d - Mammary gland" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Cell Junctions" Nucleoplasm "HPA037597: AB_2675569, HPA037598: AB_10696941" "unprognostic (1.12e-1)" "unprognostic (1.24e-1)" "unprognostic (1.59e-3)" "unprognostic (1.49e-1)" "unprognostic (6.64e-2)" "unprognostic (7.78e-2)" "unprognostic (9.31e-3)" "prognostic favorable (5.88e-4)" "unprognostic (2.15e-1)" "unprognostic (1.70e-1)" "unprognostic (1.88e-1)" "unprognostic (2.26e-1)" "prognostic favorable (2.79e-14)" "unprognostic (2.46e-1)" "unprognostic (1.88e-1)" "unprognostic (4.66e-2)" "unprognostic (1.03e-2)" 3.8 2.7 0.1 5.7 1.0 8.8 9.7 4.7 2.2 6.4 0.1 10.7 6.0 5.1 1.9 37.1 11.8 6.4 6.6 0.4 0.0 12.2 1.9 10.1 2.6 0.0 0.0 3.4 12.1 11.8 2.2 11.7 0.1 8.0 9.3 9.7 7.6 4.8 13.8 24.8 7.2 8.7 0.0 2.4 8.8 9.0 0.0 3.2 14.4 14.3 6.9 9.7 9.6 1.1 5.9 0.1 0.6 0.0 0.1 0.1 23.3 1.2 0.9 4.7 7.4 45.2 27.9 0.0 0.3 3.4 3.4 10.4 3.9 7.5 10.9 0.0 7.5 0.0 1.3 2.8 0.0 0.0 0.0 0.3 11.6 0.7 0.4 0.0 0.0 2.2 1.1 0.0 6.2 10.9 2.3 0.0 1.4 8.9 2.1 1.2 13.3 0.0 0.4 19.0 1.1 0.0 2.3 11.3 0.0 3.6 89.3 1.1 0.0 1.8 12.5 0.0 1.0 0.2 0.0 0.1 0.1 10.7 0.0 0.0 7.7 9.0 3.8 2.5 5.6 0.6 4.2 2.6 7.8 0.5 7.9 5.7 3.1 5.0 1.5 0.1 1.1 5.1 0.1 1.0 4.7 2.2 0.4 0.0 0.0 0.0 0.1 0.0 0.0 1.1 1.6 44.8 48.3 10.4 5.5 23.1 10.9 9.5 7.4 1.1 14.7 8.6 12.1 10.0 24.3 14.7 16.7 50.0 9.8 15.3 9.8 5.5 82.3 9.3 0.6 11.7 6.7 4.2 76.7 12.9 3.5 2.6 11.2 6.6 1.3 0.7 2.9 3.2 5.4 3.3 30.3 10.4 8.2 4.7 5.3 20.3 0.9 8.1 7.2 12.2 16.2 24.0 4.1 4.5 2.5 6.6 7.8 0.4 5.1 7.5 12.1 9.5 19.3 8.5 0.0 1.5 7.6 5.4 9.5 48.0 61.1 46.5 16.3 0.1 11.3 17.4 MRGPRX2 MRGX2 ENSG00000183695 "MAS related GPR family member X2" Q96LB1 11 19054455-19060717 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "skin 1: 1.0" "Cell type enhanced" "Detected in single" "Melanocytes: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA055220 Approved NA NA "Cluster 31: Skin - Epidermis development" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA055220: AB_2682743" "unprognostic (1.56e-2)" "unprognostic (1.79e-1)" 0.7 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MRM3 "FLJ10581, HC90, RMTL1, RNMTL1" ENSG00000171861 "Mitochondrial rRNA methyltransferase 3" Q9HC36 17 782353-792509 "Metabolic proteins, Predicted intracellular proteins" "rRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 27.1;Distal tubular cells: 19.6;Ductal cells: 18.9;Exocrine glandular cells: 18.4;Extravillous trophoblasts: 24.6;Proximal tubular cells: 20.0;Syncytiotrophoblasts: 19.6;Theca cells: 28.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022534, HPA023031, HPA023292" Enhanced Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA022534: AB_1856386, HPA023031: AB_1856387, HPA023292: AB_1856388" "unprognostic (1.66e-1)" "unprognostic (5.83e-3)" "unprognostic (6.72e-2)" "prognostic favorable (2.81e-4)" "unprognostic (2.67e-1)" "unprognostic (1.83e-1)" "unprognostic (2.48e-1)" "unprognostic (1.54e-1)" "unprognostic (1.46e-1)" "unprognostic (8.20e-2)" "unprognostic (3.72e-3)" "unprognostic (8.47e-2)" "prognostic favorable (3.00e-4)" "unprognostic (3.82e-2)" "unprognostic (9.98e-2)" "unprognostic (1.05e-2)" "unprognostic (1.42e-2)" 9.3 12.9 7.9 6.8 8.4 17.6 8.7 9.9 9.2 6.7 9.7 9.7 7.8 7.6 5.2 11.6 8.0 4.8 17.3 8.2 7.9 9.7 20.5 6.0 10.4 8.2 8.7 8.7 19.6 9.1 6.2 6.9 8.6 7.5 7.5 4.3 9.5 6.0 29.4 14.7 8.2 6.6 7.7 9.9 13.0 18.6 8.6 8.3 7.0 18.7 9.3 8.6 7.2 8.3 26.4 53.9 11.3 19.8 16.2 13.8 22.5 13.6 12.8 27.3 22.8 31.8 12.0 47.3 14.1 10.6 13.1 21.7 33.0 12.0 24.8 16.2 55.9 18.3 30.6 27.9 16.7 15.8 16.0 16.7 16.2 29.0 23.9 13.6 20.7 28.3 31.3 20.1 14.5 28.5 27.5 20.8 16.9 19.3 28.2 33.1 7.9 25.3 18.2 14.2 15.1 17.6 19.8 16.6 26.5 9.0 20.6 14.2 16.6 14.6 11.2 21.0 38.3 8.0 11.8 18.9 18.3 22.1 20.0 12.5 24.6 14.7 25.0 20.6 27.0 38.2 27.1 30.8 25.8 38.4 32.8 28.4 1.8 32.7 21.1 20.8 31.9 26.8 7.9 8.4 9.9 9.2 8.2 7.9 8.2 8.7 8.6 7.7 8.6 8.3 11.3 6.4 1.1 0.0 4.2 0.0 0.0 0.0 0.0 0.0 9.8 10.4 0.0 0.0 1.3 5.5 0.0 27.1 7.6 0.0 19.6 18.9 0.0 8.3 8.0 5.1 0.0 0.0 0.0 18.4 24.6 4.1 0.0 8.8 3.8 15.6 0.0 0.0 12.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 10.3 0.0 0.0 0.0 0.0 14.2 0.0 0.0 0.5 0.0 0.0 20.0 0.7 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 19.6 4.4 28.9 0.0 0.0 MRPS30 "PAP, PDCD9" ENSG00000112996 "Mitochondrial ribosomal protein S30" Q9NP92 5 44808947-44820428 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018686, HPA021149" Approved NA NA "Cluster 44: Non-specific - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 20: HeLa - Mitochondria" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA018686: AB_1854127, HPA021149: AB_1854128" "unprognostic (1.56e-1)" "unprognostic (1.23e-1)" "unprognostic (4.48e-1)" "unprognostic (2.94e-2)" "unprognostic (5.47e-2)" "unprognostic (3.54e-2)" "prognostic unfavorable (5.91e-4)" "unprognostic (1.01e-1)" "unprognostic (1.64e-2)" "unprognostic (2.15e-1)" "unprognostic (1.05e-1)" "unprognostic (2.45e-2)" "prognostic favorable (2.87e-9)" "unprognostic (2.20e-2)" "unprognostic (5.04e-1)" "unprognostic (7.01e-2)" "unprognostic (8.70e-3)" 13.1 13.4 4.0 8.5 6.3 25.3 14.1 7.3 9.0 9.5 2.6 13.8 13.4 10.3 5.9 16.6 10.5 5.8 24.5 6.2 2.1 15.1 21.4 8.5 11.7 0.5 1.9 9.4 12.9 12.7 6.4 7.5 1.1 8.7 10.8 6.4 11.6 6.4 35.6 20.5 12.0 7.3 1.9 11.3 12.0 11.5 3.5 10.1 12.0 26.7 9.6 11.4 10.9 7.6 33.2 32.5 19.2 36.9 14.0 16.3 61.9 16.2 17.4 22.8 16.1 51.9 40.5 50.4 55.1 10.7 52.6 30.6 37.7 24.2 20.3 32.7 64.5 37.5 67.8 40.8 31.1 51.5 29.8 16.2 24.4 23.9 29.4 17.2 21.7 27.4 58.5 45.6 21.4 28.3 33.3 67.7 32.4 26.0 57.6 31.3 32.1 67.6 34.6 24.1 29.3 22.9 75.1 40.1 52.2 14.5 36.2 38.0 21.4 26.8 39.6 22.3 51.0 24.4 31.0 41.0 22.6 68.4 27.7 26.0 24.0 18.7 30.9 27.2 32.3 37.8 34.2 34.2 25.6 31.7 40.0 33.9 4.4 35.2 33.3 19.4 46.1 33.6 4.0 6.3 7.3 9.0 6.2 2.1 0.5 1.9 1.1 1.9 3.5 7.6 22.1 25.6 16.5 4.6 31.7 48.8 38.8 63.3 26.7 31.3 23.6 21.1 60.2 17.2 31.5 5.5 18.8 40.0 37.6 21.4 33.2 36.5 105.1 21.3 29.4 23.9 28.7 18.7 14.4 33.1 38.0 24.1 21.4 22.5 19.0 24.1 17.9 26.9 32.5 32.0 8.0 24.5 30.5 16.6 15.7 14.3 20.8 18.9 17.8 3.7 26.3 20.4 26.8 3.5 6.9 29.6 22.8 18.0 20.1 27.6 25.6 35.4 21.9 26.3 13.1 24.9 28.7 43.4 26.4 28.6 75.0 18.6 32.6 32.6 37.0 42.3 MS4A2 "APY, FCER1B, IGER, MS4A1" ENSG00000149534 "Membrane spanning 4-domains A2" Q01362 11 60088261-60098467 "FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "IgE-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 12.6" "Cell type enriched" "Detected in some" 20 "granulocytes: 967.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 908 "basophil: 275.5" "Lineage enriched" "Detected in single" 1467 "granulocytes: 275.5" "Cell line enhanced" "Detected in some" "HEL: 2.7;THP-1: 1.3" "Not detected" "Not detected" "Region enhanced" "Detected in all" "spinal cord: 15.3" HPA059967 Enhanced NA NA "Cluster 38: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 36: HEL - Hemostasis" "Cluster 60: Granulocytes - Receptor signaling" "HPA059967: AB_2684183" "unprognostic (7.28e-2)" "unprognostic (9.21e-2)" "unprognostic (2.50e-4)" "unprognostic (4.97e-2)" "unprognostic (4.47e-1)" "unprognostic (2.40e-6)" "unprognostic (1.88e-2)" "unprognostic (6.21e-3)" "unprognostic (3.96e-1)" "unprognostic (1.21e-1)" "unprognostic (1.41e-1)" "unprognostic (6.63e-3)" "unprognostic (6.49e-3)" "unprognostic (9.95e-2)" "unprognostic (4.03e-2)" "unprognostic (1.57e-1)" "unprognostic (1.74e-1)" 2.6 0.2 0.3 2.4 0.3 0.9 2.7 0.5 0.5 6.3 0.6 4.9 5.5 4.2 3.7 4.8 0.9 8.2 0.6 0.3 0.3 0.5 0.4 12.6 1.1 0.4 0.3 0.1 0.5 0.3 0.1 0.3 0.4 3.0 5.4 0.0 1.8 2.4 2.9 2.5 6.7 4.1 0.3 0.2 5.3 1.0 0.3 1.2 0.1 1.2 1.8 3.8 2.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.7 0.2 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 275.5 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.1 0.1 0.1 0.0 0.4 0.3 0.3 0.5 0.5 0.3 0.3 0.4 0.3 0.4 0.3 0.3 0.5 0.1 0.0 30.9 0.0 0.3 0.0 0.9 0.0 0.0 0.3 0.1 0.1 0.5 0.0 6.8 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.4 0.1 0.1 0.3 0.0 46.7 0.1 0.0 0.1 1.1 0.0 0.1 967.4 0.0 0.4 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.3 0.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.5 0.0 0.0 0.7 0.4 0.0 0.7 0.2 0.1 0.1 0.0 0.0 0.0 12.2 0.0 0.0 0.2 MS4A4A "CD20L1, MS4A4, MS4A7" ENSG00000110079 "Membrane spanning 4-domains A4A" Q96JQ5 11 60185657-60318080 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 63.1" "Group enriched" "Detected in many" 7 "Hofbauer cells: 376.8;Kupffer cells: 445.0;Macrophages: 264.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "intermediate monocyte: 61.2;myeloid DC: 27.6;non-classical monocyte: 82.9;plasmacytoid DC: 27.7" "Group enriched" "Detected in many" 30 "dendritic cells: 27.7;monocytes: 82.9" "Cell line enhanced" "Detected in some" "HEL: 35.6;HMC-1: 45.8;K-562: 154.9" HPA029323 Approved NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 1: K-562 - Erythropoiesis" "Cluster 4: Macrophages - Innate immune response" "HPA029323: AB_10601866" "unprognostic (7.93e-2)" "unprognostic (2.05e-2)" "unprognostic (1.37e-3)" "unprognostic (1.98e-1)" "unprognostic (4.46e-2)" "unprognostic (2.31e-1)" "unprognostic (9.66e-2)" "unprognostic (1.59e-1)" "unprognostic (4.56e-1)" "unprognostic (6.65e-2)" "unprognostic (8.10e-2)" "unprognostic (2.11e-1)" "unprognostic (5.02e-3)" "unprognostic (3.32e-2)" "unprognostic (4.66e-2)" "unprognostic (4.89e-2)" "unprognostic (4.21e-2)" 42.8 24.7 3.5 16.5 3.6 6.1 12.3 3.7 8.6 14.1 4.4 14.0 5.2 4.9 3.4 8.9 11.6 25.8 8.4 3.5 3.9 4.8 15.4 28.0 31.3 4.2 3.4 4.1 4.0 3.3 3.3 63.1 3.6 3.4 16.1 2.0 7.6 4.9 2.3 2.9 13.5 20.0 2.5 33.3 6.6 3.0 5.5 11.5 3.7 10.4 7.5 28.0 3.3 4.3 0.3 0.1 0.1 0.6 0.0 0.2 0.7 0.6 0.0 0.2 0.4 0.3 0.9 0.8 0.4 0.0 0.4 0.3 0.5 0.1 0.6 1.6 0.0 35.6 0.7 0.6 0.1 1.2 45.8 0.4 0.3 0.2 0.8 0.2 0.0 0.4 154.9 4.2 0.6 0.7 0.6 0.9 0.7 0.3 0.1 0.7 0.0 2.5 0.1 1.5 0.5 0.5 0.3 0.3 0.1 0.7 0.7 8.9 0.8 1.5 0.6 0.4 0.2 6.0 0.7 0.5 0.2 0.8 0.2 0.1 9.9 0.0 0.1 61.2 0.2 1.0 0.1 0.1 27.6 0.3 0.2 0.1 0.9 1.8 82.9 27.7 0.1 6.0 3.5 3.6 3.7 8.6 3.5 3.9 4.2 3.4 3.6 2.5 5.5 4.3 2.3 0.0 7.9 0.0 3.0 1.8 0.1 0.0 0.6 0.0 0.3 2.2 3.4 2.8 2.5 0.0 0.0 1.8 7.5 0.0 0.0 0.0 0.7 0.0 0.0 5.7 0.0 13.0 0.1 0.0 2.0 1.6 0.0 0.0 7.6 0.0 47.5 4.6 376.8 0.0 0.1 0.0 0.0 445.0 24.9 1.0 0.9 264.6 3.6 10.3 8.3 0.4 0.0 0.0 0.2 0.2 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.1 13.1 1.2 1.1 0.1 0.2 0.7 1.8 3.6 1.5 0.1 0.0 0.1 MSMO1 "DESP4, ERG25, SC4MOL" ENSG00000052802 "Methylsterol monooxygenase 1" Q15800 4 165327667-165343164 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 575.6" "Cell type enhanced" "Detected in all" "Hepatocytes: 532.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "GAMG: 416.2;Karpas-707: 412.3;RPTEC TERT1: 399.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055073, HPA056127" Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 85: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum" "HPA055073: , HPA056127: AB_2683045" "unprognostic (5.76e-2)" "prognostic unfavorable (2.97e-4)" "unprognostic (3.35e-2)" "unprognostic (7.85e-2)" "unprognostic (1.74e-1)" "unprognostic (1.20e-2)" "unprognostic (7.14e-2)" "unprognostic (1.75e-2)" "unprognostic (3.52e-2)" "unprognostic (2.06e-1)" "unprognostic (3.22e-3)" "unprognostic (2.28e-1)" "prognostic favorable (9.21e-4)" "unprognostic (2.39e-1)" "unprognostic (1.56e-2)" "unprognostic (3.54e-1)" "unprognostic (1.40e-1)" 18.3 95.2 36.7 20.9 48.2 10.4 66.2 45.1 47.5 57.1 37.4 39.2 75.7 19.1 97.0 145.7 20.9 21.7 18.5 43.9 59.2 52.6 575.6 70.3 20.7 90.5 58.4 25.7 22.6 42.9 18.4 22.9 78.6 58.9 32.9 26.1 34.7 12.1 5.5 82.5 38.1 16.5 45.0 11.0 31.5 52.8 48.4 13.4 22.4 6.5 27.0 20.2 67.0 61.1 89.1 21.7 198.8 36.4 97.7 312.0 37.5 35.3 159.0 44.7 123.4 41.5 372.9 43.4 20.6 43.1 416.2 71.7 101.6 366.3 49.4 37.7 63.0 20.0 20.0 127.6 194.9 35.8 26.8 192.6 237.6 163.6 100.6 61.1 58.8 55.7 35.3 412.3 74.6 45.7 32.6 58.2 115.6 46.9 21.0 16.8 21.8 132.3 399.5 102.5 39.7 30.0 54.5 77.9 33.9 121.7 36.1 44.7 67.6 20.6 36.1 18.5 24.7 75.9 86.5 58.6 43.9 36.0 28.5 13.7 8.6 8.8 34.0 11.6 25.4 40.6 31.8 31.4 15.0 37.6 34.3 35.6 6.1 24.9 20.5 19.3 31.0 29.2 36.7 48.2 45.1 47.5 43.9 59.2 90.5 58.4 78.6 45.0 48.4 61.1 16.9 51.3 168.0 70.5 28.9 36.1 70.1 189.2 21.6 33.8 81.9 23.0 10.7 40.0 160.0 69.9 27.1 55.6 20.7 130.8 35.2 67.9 6.4 27.6 12.2 30.4 60.7 53.9 33.6 71.7 87.0 24.1 35.2 44.4 47.7 83.0 27.8 532.0 28.3 35.3 22.8 72.8 170.9 28.0 11.5 7.0 24.8 18.3 32.0 10.3 23.6 27.2 17.5 42.7 49.6 86.8 85.7 18.8 10.9 138.3 46.0 38.4 103.2 50.4 19.7 5.6 35.1 8.7 15.4 84.6 115.1 123.0 22.3 136.1 36.9 129.0 MTA2 "MTA1-L1, MTA1L1" ENSG00000149480 "Metastasis associated 1 family member 2" O94776 11 62593214-62601865 "Plasma proteins, Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 34.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005315, HPA006214, CAB017522, HPA072727" Supported Enhanced Nucleoplasm NA NA 10000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 59: Non-specific - Transcription" Nucleoplasm "CAB005315: AB_2146965, CAB017522: AB_831564, HPA006214: AB_1079421, HPA072727: " "unprognostic (5.97e-3)" "unprognostic (1.63e-2)" "unprognostic (1.23e-1)" "unprognostic (3.04e-2)" "unprognostic (3.48e-1)" "unprognostic (3.66e-2)" "prognostic unfavorable (4.82e-5)" "unprognostic (3.32e-3)" "unprognostic (1.95e-1)" "unprognostic (5.38e-3)" "unprognostic (3.09e-2)" "unprognostic (1.59e-1)" "unprognostic (1.16e-3)" "unprognostic (3.16e-3)" "unprognostic (9.84e-2)" "unprognostic (2.23e-1)" "unprognostic (2.50e-2)" 41.6 34.4 44.4 46.2 46.7 60.7 35.7 45.7 45.3 40.2 38.2 40.0 31.0 37.2 28.7 79.3 33.4 32.6 29.7 44.3 44.1 31.9 30.3 37.8 70.1 49.0 46.1 37.8 23.0 30.2 31.8 39.1 49.4 37.0 47.4 119.8 37.3 36.7 21.2 74.7 40.1 43.8 46.1 60.7 33.9 30.4 45.8 90.2 26.8 24.1 91.8 51.7 47.2 52.7 97.1 83.4 129.8 171.1 57.0 53.2 88.8 80.0 112.3 157.5 114.7 79.7 82.7 137.0 84.0 106.3 84.3 127.2 177.2 222.1 132.8 136.4 87.9 146.4 91.2 81.0 88.3 167.2 180.0 59.6 122.6 111.3 164.1 74.8 148.3 140.4 164.2 106.1 114.6 189.0 213.9 212.1 112.3 91.7 95.1 201.5 92.4 160.6 112.1 143.4 102.9 94.2 83.5 118.2 67.6 102.4 138.9 113.2 104.5 87.9 80.4 100.4 94.0 78.3 109.4 191.8 64.4 120.4 86.9 7.3 7.2 9.9 18.6 12.6 15.6 13.9 15.2 13.5 11.8 10.0 14.0 14.3 3.1 12.1 16.4 13.8 13.5 6.7 44.4 46.7 45.7 45.3 44.3 44.1 49.0 46.1 49.4 46.1 45.8 52.7 22.9 3.2 3.9 2.3 16.9 13.4 4.2 4.2 34.1 0.0 11.3 7.9 3.7 1.5 4.9 1.8 0.0 15.3 16.5 12.1 5.9 5.1 0.8 5.2 10.0 12.0 12.0 20.8 1.5 9.5 8.3 8.6 15.3 9.5 10.8 7.5 13.2 8.2 8.9 0.0 1.6 11.9 4.1 12.8 7.6 0.7 5.0 8.9 1.8 2.8 8.9 0.0 9.2 2.0 2.7 9.7 8.2 4.1 24.1 4.2 6.6 2.7 0.9 0.0 0.0 8.2 11.7 5.9 5.2 32.5 11.2 18.9 18.1 13.6 12.2 4.5 MTA3 KIAA1266 ENSG00000057935 "Metastasis associated 1 family member 3" Q9BTC8 2 42494569-42756947 "Plasma proteins, Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 70.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 137.0;Oligodendrocyte precursor cells: 106.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039433 Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 44: Non-specific - Transcription" "Cluster 63: T-cells - Adaptive immune response" "Cluster 5: NTERA-2 - Transcription" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm Vesicles "HPA039433: AB_10794747" "unprognostic (5.40e-2)" "unprognostic (4.89e-2)" "unprognostic (5.28e-2)" "prognostic unfavorable (2.30e-4)" "unprognostic (4.13e-2)" "unprognostic (2.88e-1)" "prognostic unfavorable (4.69e-4)" "unprognostic (7.55e-2)" "unprognostic (2.04e-1)" "unprognostic (5.43e-2)" "unprognostic (2.27e-1)" "unprognostic (1.58e-1)" "unprognostic (2.64e-2)" "unprognostic (9.03e-2)" "unprognostic (2.05e-1)" "unprognostic (3.47e-1)" "unprognostic (1.28e-2)" 11.8 41.8 16.4 5.6 18.9 1.6 14.9 9.1 19.4 18.5 7.1 16.6 7.8 16.8 27.5 21.8 16.1 10.0 12.4 21.9 14.9 13.6 7.9 8.8 10.7 12.3 13.9 29.2 18.8 17.3 15.1 15.3 18.8 14.4 13.2 9.3 13.6 16.8 9.1 19.1 11.4 12.0 11.7 7.8 16.8 21.0 16.1 70.4 12.6 9.9 14.5 15.3 17.8 14.8 13.0 16.6 20.1 14.3 17.4 28.0 46.6 7.4 18.6 21.7 19.2 22.2 26.2 45.4 12.6 22.1 15.9 8.2 51.6 25.2 34.2 14.1 21.0 6.7 8.8 36.4 21.9 5.0 29.0 29.5 29.1 13.4 16.6 28.1 30.4 23.9 16.5 6.1 25.7 27.8 30.3 22.0 84.4 20.8 9.7 18.4 18.9 0.0 25.7 12.1 12.3 37.1 13.5 45.5 17.8 61.6 23.2 7.0 14.2 8.9 12.1 7.2 8.1 11.5 4.7 63.5 12.6 5.7 11.1 2.5 0.9 0.0 1.7 0.6 2.6 1.2 2.0 2.9 1.5 1.3 4.4 3.0 0.2 1.8 0.9 0.4 1.1 1.5 16.4 18.9 9.1 19.4 21.9 14.9 12.3 13.9 18.8 11.7 16.1 14.8 12.7 12.8 12.5 60.4 10.8 15.3 21.1 33.0 15.4 0.0 24.6 19.6 12.5 15.7 25.7 22.0 0.0 58.5 5.1 19.1 17.6 22.9 10.7 44.5 23.1 13.1 9.6 2.5 137.0 28.0 42.0 21.7 31.1 32.3 12.0 72.3 20.7 13.3 12.4 0.0 81.8 20.0 50.8 6.6 7.1 26.0 33.8 5.2 17.8 53.4 6.9 0.0 9.2 106.1 65.9 20.2 21.8 39.9 10.9 17.7 25.2 33.1 18.4 0.0 13.1 15.8 35.9 25.5 41.1 24.5 18.3 59.9 12.6 44.5 21.5 17.3 MUC7 "FLJ27047, MG2" ENSG00000171195 "Mucin 7, secreted" Q8TAX7 4 70430492-70482997 "Disease related genes, Predicted secreted proteins" Asthma "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 875 "salivary gland: 26019.1" "Cell type enriched" "Detected in some" 12 "Melanocytes: 12.4" "Group enriched" "Detected in some" 12 "head and neck cancer: 8.1;melanoma: 2.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA006411 Enhanced "Secreted to digestive system" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 48: Smooth muscle cells - ECM organization" "HPA006411: AB_1854204" "unprognostic (5.49e-2)" "unprognostic (3.20e-1)" "unprognostic (1.06e-1)" 1.2 5.3 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.7 0.0 1.0 0.0 0.1 0.0 2.1 0.0 0.0 6.6 0.0 0.0 1.0 3.7 0.6 0.0 0.0 0.7 6.5 29.7 0.0 1.9 3.2 0.0 0.8 0.0 0.0 26019.1 0.0 2.6 3.6 1.5 0.0 0.0 1.0 1.1 1.5 0.2 0.0 1.3 0.1 0.4 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 12.4 1.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MYBPC1 ssMyBP-C ENSG00000196091 "Myosin binding protein C1" Q00872 12 101568353-101686028 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell adhesion" "Actin-binding, Muscle protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 87 "skeletal muscle: 11290.5;tongue: 5207.7" "Cell type enhanced" "Detected in some" "Astrocytes: 34.6;Breast glandular cells: 102.4;Breast myoepithelial cells: 81.4;Cardiomyocytes: 64.7;Skeletal myocytes: 184.6" "Cancer enhanced" "Detected in many" "prostate cancer: 33.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 11 "HAP1: 6.8" "Group enriched" "Detected in many" 9 "cerebellum: 39.6;olfactory bulb: 10.6" "Region enhanced" "Detected in many" "thalamus: 6.9" "HPA021004, HPA027614" Enhanced NA NA 240000 "Cluster 33: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 37: Myocytes - Muscle contraction" "HPA021004: AB_1854232, HPA027614: AB_10602711" "prognostic favorable (4.76e-5)" "unprognostic (7.72e-2)" "unprognostic (1.09e-1)" "unprognostic (1.81e-2)" "unprognostic (3.33e-2)" "unprognostic (4.63e-2)" "unprognostic (8.67e-2)" "unprognostic (2.93e-1)" "unprognostic (9.98e-3)" "unprognostic (2.56e-1)" "unprognostic (2.55e-1)" "unprognostic (1.19e-2)" "unprognostic (4.10e-2)" "unprognostic (7.96e-2)" "unprognostic (6.13e-2)" "unprognostic (5.55e-3)" 1.5 0.3 55.5 0.1 66.5 0.0 63.7 60.4 71.6 1.9 36.3 4.5 0.1 0.2 1.1 94.7 0.8 0.3 1.8 50.1 59.5 0.3 0.7 0.7 0.0 52.3 64.5 0.5 1.1 0.0 0.3 0.0 55.0 83.5 0.8 0.0 48.4 0.3 11290.5 6.1 7.4 0.0 49.4 0.4 1.3 3.4 68.4 2.6 1.2 5207.7 4.0 0.3 0.7 49.9 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.5 66.5 60.4 71.6 50.1 59.5 52.3 64.5 55.0 49.4 68.4 49.9 1.3 0.0 0.0 34.6 0.3 0.0 2.2 0.0 0.0 0.0 102.4 81.4 64.7 0.0 0.0 0.0 0.0 0.0 0.6 2.7 0.0 0.0 16.5 0.1 0.1 1.2 0.0 0.0 5.3 0.0 0.0 3.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.2 0.0 0.8 0.3 23.7 0.6 1.2 1.8 1.0 0.0 0.0 0.0 0.5 0.5 0.1 1.6 0.4 0.0 16.3 0.3 0.1 0.0 0.0 0.0 184.6 2.7 1.4 1.4 0.0 0.0 0.0 0.7 0.0 0.3 2.9 MYCT1 "FLJ21269, MTLC" ENSG00000120279 "MYC target 1" Q8N699 6 152697895-152724567 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 49.6" "Group enriched" "Detected in some" 5 "Adipocytes: 123.0;Endothelial cells: 141.3;Hepatic stellate cells: 230.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 33 "eosinophil: 30.7" "Lineage enriched" "Detected in single" 248 "granulocytes: 30.7" "Group enriched" "Detected in some" 5 "HUVEC TERT2: 124.6;TIME: 104.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA047992 Approved Nucleoplasm,Vesicles NA NA 120000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Vesicles "HPA047992: " "unprognostic (2.92e-1)" "unprognostic (1.82e-1)" "unprognostic (5.95e-2)" "unprognostic (2.06e-1)" "unprognostic (6.73e-2)" "unprognostic (6.80e-2)" "unprognostic (4.64e-3)" "unprognostic (6.78e-2)" "unprognostic (9.90e-2)" "unprognostic (2.10e-1)" "unprognostic (2.66e-2)" "unprognostic (2.18e-2)" "prognostic unfavorable (4.73e-4)" "unprognostic (1.26e-3)" "unprognostic (1.08e-1)" "unprognostic (1.25e-1)" "unprognostic (3.36e-2)" 26.6 3.2 6.8 5.2 6.9 1.2 21.4 6.9 10.2 9.0 5.2 6.1 3.5 10.1 4.5 4.6 9.2 10.5 17.1 6.3 7.1 6.6 13.1 15.6 6.2 7.7 6.9 3.6 2.7 4.3 2.2 20.7 8.6 4.4 5.8 1.0 3.7 3.8 12.8 4.7 5.6 12.4 6.8 49.6 4.5 1.8 10.0 2.5 12.2 20.5 3.0 8.1 7.3 7.5 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.0 17.7 0.1 0.0 0.2 0.0 0.1 0.0 23.0 0.3 0.0 0.7 0.1 0.1 0.0 0.2 0.2 0.3 0.0 124.6 0.0 0.3 0.3 0.4 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 2.1 0.0 0.0 104.4 0.5 0.8 1.5 0.0 1.1 0.0 15.6 0.0 0.0 0.0 0.9 0.0 30.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.1 0.0 0.1 0.0 0.6 6.8 6.9 6.9 10.2 6.3 7.1 7.7 6.9 8.6 6.8 10.0 7.5 123.0 0.0 5.2 0.7 0.8 7.1 0.2 0.1 2.8 0.2 0.4 0.9 3.1 2.8 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.2 10.2 1.3 0.2 141.3 0.0 13.7 0.1 0.2 0.0 4.0 0.0 0.1 1.3 0.0 230.6 2.1 0.1 0.0 0.1 0.0 0.0 7.3 7.3 3.7 0.3 13.3 14.2 30.9 0.1 0.0 0.0 0.5 0.2 0.1 0.0 0.0 0.6 0.5 0.0 0.0 17.7 0.0 0.0 1.5 2.2 0.1 0.1 0.5 5.5 0.0 0.9 0.5 0.0 0.7 MYO7B ENSG00000169994 "Myosin VIIB" Q6PIF6 2 127535802-127637729 "Predicted intracellular proteins" Differentiation "Actin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "intestine: 113.2" "Cell type enhanced" "Detected in some" "Distal enterocytes: 127.7;Intestinal goblet cells: 48.3;Paneth cells: 74.9;Proximal enterocytes: 151.4;Undifferentiated cells: 45.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 17.2" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "classical monocyte: 5.7;naive B-cell: 5.9" "Group enriched" "Detected in many" 22 "B-cells: 5.9;dendritic cells: 2.6;monocytes: 5.7" "Cell line enriched" "Detected in some" 10 "MOLT-4: 286.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA039131 Enhanced NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 56: Intestine - Transmembrane transport" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 45: Enterocytes - Digestion" "HPA039131: AB_10672771" "unprognostic (4.10e-3)" "unprognostic (3.81e-2)" "unprognostic (3.80e-2)" "unprognostic (2.23e-4)" "unprognostic (1.14e-2)" "unprognostic (2.23e-1)" "unprognostic (2.07e-1)" "unprognostic (8.51e-2)" "unprognostic (3.76e-1)" "unprognostic (3.86e-2)" "unprognostic (2.32e-1)" "unprognostic (1.03e-1)" "prognostic favorable (1.25e-4)" "unprognostic (2.80e-2)" "unprognostic (8.76e-2)" "unprognostic (1.57e-1)" "unprognostic (2.88e-1)" 0.1 0.0 0.2 4.9 0.2 6.5 0.1 0.2 0.3 0.0 0.0 35.9 113.2 0.0 6.7 0.3 0.4 13.0 0.2 0.7 1.8 8.5 0.3 1.0 4.0 0.5 1.1 0.0 0.2 0.0 0.0 1.7 1.1 0.1 25.3 0.0 0.1 0.2 0.8 0.3 84.4 1.2 0.5 11.3 0.4 1.4 0.3 9.0 0.2 0.0 1.6 0.0 0.0 0.8 0.2 0.0 0.0 0.0 0.0 0.0 0.2 1.6 0.0 14.5 5.1 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.2 0.0 28.1 0.0 0.0 0.2 0.0 286.1 0.8 0.0 0.5 1.7 0.5 1.9 0.3 0.5 0.0 0.1 0.1 0.0 2.4 0.0 0.0 0.1 0.5 0.1 0.6 8.6 0.4 2.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 5.7 0.1 0.0 2.2 0.0 0.8 0.0 0.0 2.6 5.9 0.0 0.2 0.1 0.0 1.4 0.7 0.0 2.4 0.2 0.2 0.2 0.3 0.7 1.8 0.5 1.1 1.1 0.5 0.3 0.8 2.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 12.8 0.0 5.5 0.0 0.1 1.5 127.7 1.9 0.2 0.1 0.0 0.0 1.0 25.8 0.0 0.2 0.2 2.0 0.1 1.5 0.0 0.0 0.1 2.9 0.2 0.1 0.0 0.4 48.3 0.0 0.0 0.3 0.4 0.0 1.0 0.0 0.0 0.8 0.0 0.0 0.5 0.1 1.6 74.9 0.0 0.0 0.0 151.4 9.9 0.0 0.0 0.0 2.8 0.1 0.6 1.1 0.0 0.1 0.3 0.6 0.0 45.7 0.1 MYOCD MYCD ENSG00000141052 Myocardin Q8IZQ8 17 12665890-12768949 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 24.2" "Group enriched" "Detected in some" 5 "Cardiomyocytes: 47.3;Endometrial stromal cells: 48.5;Peritubular cells: 100.8;Sertoli cells: 26.3;Smooth muscle cells: 32.9" "Cancer enhanced" "Detected in some" "stomach cancer: 2.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 6.5;BJ hTERT+: 6.4;HBF TERT88: 10.4;hTEC/SVTERT24-B: 11.7;REH: 8.4;SuSa: 12.8" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebellum: 4.1" "CAB046485, HPA071528, HPA072582" Approved Approved Nucleoplasm NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm "CAB046485: AB_10600720, HPA071528: , HPA072582: " "unprognostic (2.82e-1)" "unprognostic (1.69e-1)" "unprognostic (2.36e-2)" "unprognostic (1.90e-1)" "unprognostic (3.79e-2)" "unprognostic (5.33e-2)" "unprognostic (2.15e-4)" "unprognostic (2.71e-2)" "unprognostic (1.61e-2)" "unprognostic (2.31e-1)" "unprognostic (1.76e-1)" "unprognostic (4.83e-2)" "unprognostic (1.01e-4)" "unprognostic (2.88e-2)" "unprognostic (1.07e-1)" "unprognostic (5.45e-2)" "unprognostic (1.91e-2)" 3.2 1.0 0.4 4.3 0.7 0.0 1.2 0.3 0.8 9.4 1.6 24.2 2.6 13.0 2.4 13.1 8.5 4.6 14.2 0.4 0.4 0.7 0.2 2.7 0.1 0.5 0.5 4.4 0.3 0.1 0.2 3.4 0.8 8.8 4.9 0.0 0.2 20.7 0.5 1.3 5.1 15.8 0.5 0.6 6.1 2.1 0.8 0.1 0.7 0.8 0.1 17.2 4.4 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 6.5 6.4 2.4 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.3 0.0 11.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 8.4 1.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 12.8 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.7 0.3 0.8 0.4 0.4 0.5 0.5 0.8 0.5 0.8 0.4 0.3 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 47.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.4 2.0 48.5 1.2 7.8 0.0 1.2 0.2 0.1 3.6 0.0 1.0 0.0 8.4 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 1.0 0.5 0.6 0.2 0.0 9.4 0.0 0.0 0.0 1.0 0.3 0.0 0.0 100.8 0.0 0.1 0.0 0.1 0.0 0.0 26.3 0.2 32.9 0.3 0.8 0.1 0.9 0.5 0.4 6.0 0.0 0.1 MZB1 "HSPC190, MEDA-7, MGC29506, PACAP, pERp1" ENSG00000170476 "Marginal zone B and B1 cell specific protein" Q8WU39 5 139387467-139390081 "Predicted secreted proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 89.8;lymphoid tissue: 272.2" "Cell type enriched" "Detected in many" 6 "Plasma cells: 4000.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "memory B-cell: 160.4;plasmacytoid DC: 569.3" "Group enriched" "Detected in many" 116 "B-cells: 160.4;dendritic cells: 569.3" "Group enriched" "Detected in some" 5 "Karpas-707: 581.5;RPMI-8226: 2193.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043745, HPA052694" Enhanced Approved "Golgi apparatus" "Secreted to blood" NA NA 350000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Golgi apparatus" "HPA043745: AB_10960359, HPA052694: AB_2681919" "unprognostic (4.97e-3)" "unprognostic (1.75e-2)" "unprognostic (4.23e-2)" "prognostic favorable (7.27e-4)" "unprognostic (2.21e-2)" "prognostic favorable (4.60e-5)" "unprognostic (6.57e-2)" "unprognostic (1.35e-1)" "unprognostic (6.45e-3)" "unprognostic (7.10e-3)" "unprognostic (2.57e-1)" "unprognostic (1.55e-1)" "prognostic unfavorable (1.15e-8)" "unprognostic (7.22e-2)" "unprognostic (3.14e-1)" "unprognostic (9.46e-2)" "unprognostic (7.36e-2)" 4.4 9.1 0.0 87.4 0.1 33.0 21.0 0.0 0.7 18.3 0.2 70.1 89.8 1.8 0.4 10.1 5.7 14.3 2.3 0.0 0.0 5.9 5.8 15.9 123.2 0.1 0.0 4.9 1.3 0.0 0.7 0.0 0.1 5.1 39.9 0.0 56.7 4.9 0.1 0.4 47.8 2.1 0.4 272.2 66.6 2.4 0.1 147.3 9.1 0.0 117.8 58.7 3.6 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 256.8 0.0 0.0 0.0 0.4 0.0 0.0 0.0 144.6 0.0 0.2 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 128.5 0.5 581.5 0.0 0.0 227.8 2.2 0.0 0.0 0.0 90.1 0.3 2193.9 0.0 0.0 0.3 0.8 0.0 11.4 0.0 0.0 3.1 0.1 0.6 0.0 1.8 0.1 0.0 262.0 16.7 223.0 0.1 0.4 0.0 0.0 0.1 0.1 1.5 0.1 3.0 160.4 0.6 1.1 0.5 75.6 0.1 0.2 3.1 2.7 0.0 569.3 0.2 26.1 0.0 0.1 0.0 0.7 0.0 0.0 0.1 0.0 0.1 0.4 0.1 0.3 0.4 6.4 10.1 0.0 665.7 2.5 1.3 0.1 0.0 0.0 3.7 3.2 1.1 4.3 2.0 0.0 0.0 0.1 235.0 0.9 0.0 0.1 0.1 1.8 0.4 2.0 1.2 49.3 0.0 0.0 0.1 2.0 6.1 0.4 2.5 0.1 11.4 14.0 0.1 0.0 0.0 1.1 0.0 7.1 3.4 1.1 0.0 4.7 540.7 0.0 1.0 0.0 4.1 0.0 0.0 0.1 0.4 0.0 4000.1 3.0 1.2 1.9 1.2 0.0 0.0 1.7 2.1 0.1 0.1 0.4 2.4 2.2 100.7 0.5 9.7 0.4 NAGLU NAG ENSG00000108784 N-acetyl-alpha-glucosaminidase P54802 17 42536241-42544449 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Charcot-Marie-Tooth disease, Disease variant, Mucopolysaccharidosis, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Theca cells: 74.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038815 Supported "Intracellular and membrane" NA NA 270000000 "Cluster 37: B-cells - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "HPA038815: AB_10697398" "unprognostic (1.53e-1)" "unprognostic (1.19e-1)" "unprognostic (6.48e-2)" "prognostic favorable (4.17e-4)" "prognostic unfavorable (6.59e-4)" "unprognostic (1.46e-1)" "unprognostic (1.75e-3)" "unprognostic (3.09e-2)" "unprognostic (2.20e-1)" "unprognostic (6.68e-2)" "prognostic favorable (6.90e-4)" "unprognostic (8.07e-2)" "prognostic favorable (2.58e-6)" "unprognostic (2.25e-1)" "unprognostic (8.74e-3)" "unprognostic (2.15e-2)" "unprognostic (1.62e-1)" 41.6 37.9 12.5 14.8 21.6 20.3 35.3 16.6 16.7 31.1 28.7 25.1 24.3 34.7 12.8 19.5 27.6 27.4 20.1 12.0 15.0 39.3 59.3 30.8 24.0 18.0 19.2 35.2 63.8 21.3 22.5 26.1 20.1 28.3 16.4 3.1 37.7 18.4 16.0 25.1 30.9 13.8 14.2 40.7 35.1 8.7 19.5 17.1 37.6 9.7 13.4 28.9 23.9 30.0 16.0 55.3 10.8 24.6 106.6 34.5 36.4 24.0 56.9 24.9 31.7 14.9 40.4 20.3 23.7 37.4 54.7 38.3 9.7 11.7 5.5 15.8 20.2 11.2 31.3 31.8 35.3 13.3 27.7 41.4 17.8 13.6 16.9 27.3 32.8 3.6 16.6 39.3 27.9 38.9 2.2 23.0 12.6 34.6 7.0 8.7 23.6 47.2 33.1 36.1 16.2 24.4 12.9 17.6 20.4 15.6 82.1 14.1 25.8 59.3 9.7 23.8 15.7 52.6 25.8 17.6 35.9 14.4 43.1 1.1 2.4 1.9 2.5 1.8 2.4 2.4 1.0 1.3 2.1 1.8 1.8 1.4 1.1 2.1 2.9 2.8 0.2 1.1 12.5 21.6 16.6 16.7 12.0 15.0 18.0 19.2 20.1 14.2 19.5 30.0 14.1 12.8 7.8 17.3 9.0 2.8 6.1 3.9 2.2 15.5 14.2 8.9 3.8 18.6 4.9 18.4 4.2 23.8 11.4 21.1 3.9 18.4 0.3 5.8 14.5 12.2 6.7 4.4 2.3 33.2 14.5 26.4 27.0 12.1 2.5 40.1 24.3 43.7 37.6 15.2 3.1 17.6 0.0 26.0 3.5 2.4 19.9 19.0 16.0 10.3 5.9 13.2 8.2 6.0 19.2 15.8 5.4 12.8 12.9 10.7 23.0 31.8 3.7 6.7 6.6 18.0 12.8 0.4 6.0 6.1 3.4 18.5 6.0 74.6 15.0 6.0 NCCRP1 "FBXO50, LOC342897, NCCRP-1" ENSG00000188505 "NCCRP1, F-box associated domain containing" Q6ZVX7 19 39196964-39201884 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 453.4;skin 1: 273.2;vagina: 181.7" "Cell type enriched" "Detected in some" 12 "monocytes: 563.9" "Group enriched" "Detected in many" 4 "cervical cancer: 42.8;head and neck cancer: 48.5;melanoma: 28.3;urothelial cancer: 33.9" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.1" "Cell line enriched" "Detected in some" 10 "SK-BR-3: 30.8" "Region enhanced" "Detected in single" "olfactory bulb: 1.6" "Low region specificity" "Detected in some" HPA052812 Approved NA NA 400000 "Cluster 17: Basophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 3: Monocytes - Immune response regulation" "HPA052812: AB_2681960" "unprognostic (3.56e-3)" "unprognostic (3.69e-2)" "unprognostic (2.08e-1)" "prognostic unfavorable (1.01e-4)" "unprognostic (4.59e-3)" "unprognostic (3.73e-3)" "unprognostic (2.78e-1)" "unprognostic (3.37e-3)" "unprognostic (1.00e-1)" "unprognostic (3.53e-3)" "unprognostic (2.04e-2)" "unprognostic (1.90e-1)" "unprognostic (6.37e-6)" "unprognostic (2.12e-1)" "unprognostic (3.00e-1)" "unprognostic (2.13e-1)" "unprognostic (1.57e-1)" 0.3 0.2 1.3 2.1 0.9 1.0 6.3 1.9 1.8 97.0 0.0 0.4 2.0 0.6 0.8 453.4 1.1 0.8 0.4 1.0 0.8 2.8 0.2 0.4 2.7 1.0 0.9 0.4 8.8 1.4 0.4 1.1 1.3 1.4 1.9 1.7 54.0 1.2 0.9 273.2 0.7 0.5 0.9 1.4 0.5 0.5 1.0 4.1 0.6 0.0 124.9 5.2 181.7 1.4 0.2 0.2 1.1 0.2 0.1 0.7 2.4 0.1 0.0 0.1 0.2 0.5 0.5 0.7 2.3 0.4 0.2 1.0 1.7 0.7 0.5 0.0 0.4 0.2 0.9 0.1 0.2 0.5 0.3 0.5 0.5 0.1 0.3 0.3 0.3 0.5 0.4 0.2 0.3 0.1 0.2 0.2 0.7 0.2 0.2 0.2 0.4 0.4 0.1 0.6 0.6 1.0 2.9 30.8 0.2 0.9 0.4 0.9 0.2 0.2 0.2 0.2 0.5 0.2 0.2 0.6 0.6 0.2 0.5 1.1 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.1 0.1 0.0 0.0 1.3 0.9 1.9 1.8 1.0 0.8 1.0 0.9 1.3 0.9 1.0 1.4 0.0 0.0 0.0 0.0 0.0 0.6 1.6 8.5 0.0 0.3 4.7 2.4 0.3 0.0 30.8 3.7 0.0 0.4 0.2 0.1 0.0 2.7 0.0 0.7 0.4 0.2 0.0 0.0 0.0 2.3 3.1 1.0 0.0 2.5 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 6.1 0.0 4.7 0.2 0.0 0.7 1.8 0.0 563.9 0.3 0.0 0.0 0.0 4.2 0.7 0.0 1.2 1.1 0.0 0.1 1.6 0.0 0.0 0.1 2.0 0.1 0.5 7.3 7.1 11.1 0.2 0.1 0.0 46.4 NDE1 "FLJ20101, NDE, nudE" ENSG00000072864 "NudE neurodevelopment protein 1" Q9NXR1 16 15643267-15734691 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Mitosis, Neurogenesis" "Developmental protein" Lissencephaly "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 105.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "granulocytes: 21.8;monocytes: 11.7;NK-cells: 8.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024075 Approved NA Yes "Cluster 14: Monocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 63: NK-cells & T-cells - Immune response" "HPA024075: AB_1854336" "unprognostic (1.09e-1)" "unprognostic (1.66e-1)" "unprognostic (3.26e-1)" "unprognostic (1.47e-1)" "unprognostic (3.84e-1)" "unprognostic (4.11e-2)" "prognostic unfavorable (9.92e-4)" "unprognostic (1.43e-2)" "unprognostic (1.59e-1)" "unprognostic (4.55e-2)" "unprognostic (3.70e-3)" "unprognostic (1.16e-1)" "prognostic unfavorable (8.19e-4)" "unprognostic (1.29e-1)" "unprognostic (3.28e-2)" "unprognostic (2.22e-1)" "unprognostic (2.93e-2)" 9.2 5.8 12.1 13.0 23.6 25.6 9.4 22.5 15.6 14.6 6.9 25.0 7.5 11.6 2.6 17.7 11.1 9.8 10.6 11.2 16.1 6.3 4.2 11.1 20.4 30.0 24.5 7.5 4.0 4.0 3.1 10.0 26.5 14.2 7.3 2.0 12.2 5.1 7.3 27.6 12.9 10.7 17.0 12.5 10.1 11.1 21.3 23.4 6.3 7.9 20.9 15.3 19.8 43.2 37.0 33.0 34.2 39.9 11.4 18.6 10.4 15.4 21.0 30.4 34.5 18.3 58.3 21.9 24.0 23.2 16.7 34.5 25.3 47.3 20.8 33.7 16.0 24.6 35.3 51.7 16.3 33.3 37.2 6.6 28.9 28.8 52.0 16.9 40.6 27.9 20.5 80.5 26.6 43.9 43.0 30.5 30.5 26.5 14.3 64.8 32.3 34.8 11.6 24.1 17.0 21.0 27.5 40.7 27.6 25.9 42.8 34.3 12.5 26.9 17.6 43.2 36.1 17.4 13.1 38.1 27.5 43.0 55.0 5.1 4.7 15.0 3.0 3.8 1.7 3.3 3.0 1.3 3.4 1.9 1.8 2.0 21.8 8.5 11.7 3.1 3.3 3.9 12.1 23.6 22.5 15.6 11.2 16.1 30.0 24.5 26.5 17.0 21.3 43.2 11.7 3.2 4.4 11.1 36.1 26.0 32.7 19.0 24.5 7.0 9.5 10.4 2.0 4.3 8.9 5.5 6.2 3.9 25.0 9.6 0.0 4.5 46.9 17.1 23.1 11.6 4.2 49.0 2.1 5.3 5.3 11.8 19.4 15.0 10.8 15.5 8.6 1.7 10.1 3.3 2.4 7.4 2.0 15.8 11.0 58.5 15.8 19.3 12.4 22.5 53.0 7.4 50.4 9.5 105.5 7.1 4.2 6.0 16.6 26.3 4.6 1.9 13.3 6.5 6.6 6.9 9.5 13.8 10.0 18.8 30.7 2.5 28.3 9.8 10.2 21.6 NDFIP2 "KIAA1165, N4wbp5a" ENSG00000102471 "Nedd4 family interacting protein 2" Q9NV92 13 79481124-79556075 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 342.7;Late spermatids: 290.4;Suprabasal keratinocytes: 367.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 12.1;eosinophil: 22.7;naive CD4 T-cell: 5.6" "Group enriched" "Detected in many" 16 "granulocytes: 22.7;T-cells: 5.6" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009160 Uncertain Supported Vesicles NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" Vesicles "HPA009160: AB_1079456" "unprognostic (2.56e-1)" "unprognostic (5.51e-3)" "unprognostic (1.95e-3)" "unprognostic (9.61e-2)" "unprognostic (2.60e-1)" "prognostic unfavorable (5.99e-4)" "unprognostic (1.50e-1)" "unprognostic (5.53e-2)" "unprognostic (2.30e-1)" "unprognostic (3.12e-1)" "unprognostic (1.52e-2)" "unprognostic (2.63e-2)" "prognostic favorable (4.18e-5)" "unprognostic (1.32e-1)" "unprognostic (1.31e-1)" "unprognostic (6.47e-2)" "unprognostic (1.02e-1)" 13.9 19.2 17.0 11.4 20.9 2.6 22.7 10.0 25.2 15.5 7.0 42.7 52.7 10.1 22.5 54.4 17.1 20.1 26.0 27.1 8.1 45.9 46.3 17.7 13.0 10.1 7.3 7.0 31.8 29.6 6.4 31.9 12.3 22.7 47.0 21.7 21.4 15.6 30.9 71.3 64.3 9.1 10.6 11.7 25.9 18.1 9.2 16.0 19.3 19.9 19.6 35.6 25.2 21.5 134.6 22.6 23.2 29.4 27.7 50.3 43.6 48.5 66.9 50.1 83.0 49.9 146.1 5.6 32.6 64.0 28.5 178.2 20.5 84.9 75.3 69.7 57.1 6.2 66.5 27.1 50.5 106.2 17.8 40.4 109.3 33.4 52.7 55.8 24.1 10.4 27.5 10.0 56.8 19.3 8.7 24.1 17.1 109.7 22.7 0.5 45.7 25.2 123.1 76.7 23.3 33.4 54.9 52.4 40.0 37.8 43.8 88.2 20.4 16.0 20.4 31.1 32.8 37.6 44.2 21.1 65.6 0.5 65.6 12.1 0.0 22.7 3.2 0.0 2.7 0.2 2.8 2.6 0.0 0.6 5.6 3.1 0.1 0.8 0.0 0.2 3.2 2.4 17.0 20.9 10.0 25.2 27.1 8.1 10.1 7.3 12.3 10.6 9.2 21.5 17.5 41.7 28.9 26.4 4.4 342.7 137.0 180.6 118.4 30.9 32.7 18.8 29.4 57.2 93.2 47.8 6.2 112.6 6.9 161.0 23.5 85.6 271.2 51.5 17.2 22.0 69.4 4.2 189.0 72.2 152.7 33.2 31.1 49.8 88.2 11.5 20.7 69.2 14.4 16.8 44.2 88.1 95.6 17.0 23.5 290.4 17.4 4.0 33.8 27.2 2.7 22.8 5.2 42.3 100.3 101.7 96.7 12.8 13.8 105.6 204.3 104.6 112.6 15.5 13.1 22.2 24.0 56.5 45.1 102.2 367.7 109.7 24.9 35.2 73.3 145.5 NDUFC2 "B14.5b, HLC-1" ENSG00000151366 "NADH:ubiquinone oxidoreductase subunit C2" O95298 11 78068297-78079862 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA038873, HPA056195" Approved Supported Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 39: CACO-2 - Unknown function" "Cluster 2: Hepatocytes - Metabolism" Mitochondria "HPA038873: AB_10673480, HPA056195: AB_2683063" "unprognostic (7.32e-2)" "unprognostic (5.91e-3)" "unprognostic (4.00e-2)" "unprognostic (6.14e-2)" "unprognostic (1.94e-1)" "unprognostic (8.97e-2)" "unprognostic (1.60e-1)" "unprognostic (4.23e-3)" "unprognostic (4.75e-3)" "unprognostic (3.32e-3)" "unprognostic (1.34e-1)" "unprognostic (2.11e-1)" "prognostic favorable (5.00e-5)" "unprognostic (6.32e-2)" "unprognostic (3.01e-1)" "unprognostic (4.18e-2)" "unprognostic (3.61e-3)" 202.3 278.0 118.8 84.5 126.1 126.1 143.0 128.7 150.7 103.0 125.6 143.6 218.4 125.3 68.4 142.6 120.2 108.6 240.7 129.0 145.8 151.1 286.8 100.0 109.1 121.6 117.1 96.2 168.8 186.1 133.5 74.8 124.2 88.7 66.1 59.8 275.1 83.2 487.6 121.9 194.3 63.6 136.8 96.2 130.0 103.0 126.1 73.5 207.0 254.0 62.8 97.1 100.1 136.3 287.6 342.2 183.3 118.8 168.3 105.6 227.2 335.7 190.9 252.4 179.9 910.4 311.8 166.3 583.3 155.8 210.2 293.1 136.1 190.9 99.5 318.8 386.7 183.8 337.4 727.9 270.9 409.7 164.2 147.9 177.8 195.6 75.2 156.0 172.9 158.8 365.3 278.4 137.9 478.7 254.5 722.4 212.4 670.4 415.6 224.5 352.5 570.5 196.4 420.7 261.2 229.0 235.0 499.5 182.3 158.8 391.4 328.2 241.0 256.4 314.9 611.8 297.9 251.5 541.9 400.4 146.4 236.6 251.0 374.5 337.6 354.0 150.1 293.0 138.3 230.8 172.4 163.4 363.5 212.1 144.5 159.8 102.2 225.4 243.0 290.4 202.7 410.9 118.8 126.1 128.7 150.7 129.0 145.8 121.6 117.1 124.2 136.8 126.1 136.3 256.6 166.7 194.7 0.0 106.4 95.5 166.1 443.7 40.5 145.8 346.2 414.0 240.9 243.1 288.2 391.8 66.7 408.8 166.4 206.3 305.2 395.6 311.8 413.8 129.3 183.7 167.9 106.5 0.0 431.5 392.8 165.7 43.3 241.7 153.2 158.1 184.9 856.9 346.2 90.9 0.0 317.9 429.3 174.5 110.7 84.7 215.6 129.4 245.5 0.0 246.7 310.0 175.1 0.0 0.0 456.5 329.1 201.6 102.5 239.0 461.8 454.6 300.0 131.6 236.7 154.5 222.7 384.4 162.1 67.5 114.4 387.1 109.9 226.3 373.2 215.6 NEDD9 "CAS-L, CASS2, HEF1" ENSG00000111859 "Neural precursor cell expressed, developmentally down-regulated 9" Q14511 6 11183298-11382348 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Cell cycle, Cell division, Growth regulation, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 323.2;Alveolar cells type 1: 471.1;Glandular and luminal cells: 337.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "EFO-21: 137.3;HSkMC: 67.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009689, CAB009720, HPA038768, HPA039270, HPA072955" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA Yes "Cluster 8: Neutrophils - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB009720: , HPA009689: , HPA038768: AB_2676196, HPA039270: AB_2676422, HPA072955: " "unprognostic (2.83e-3)" "unprognostic (2.33e-2)" "unprognostic (1.08e-2)" "unprognostic (6.93e-2)" "unprognostic (2.12e-1)" "unprognostic (1.16e-1)" "unprognostic (1.62e-1)" "unprognostic (9.54e-2)" "unprognostic (3.05e-2)" "unprognostic (2.09e-1)" "unprognostic (2.90e-1)" "unprognostic (1.64e-1)" "unprognostic (5.59e-3)" "unprognostic (2.25e-2)" "unprognostic (2.37e-1)" "unprognostic (2.41e-1)" "unprognostic (1.05e-1)" 94.7 8.6 8.3 23.3 8.1 8.6 64.2 6.4 12.3 26.6 14.4 30.7 15.5 19.2 17.5 14.5 22.7 31.4 32.7 7.7 6.4 33.8 20.7 91.9 25.8 8.3 7.3 8.3 17.1 9.5 8.1 69.2 8.5 22.4 30.2 9.8 26.7 29.8 27.2 20.6 38.1 25.8 7.4 25.2 23.5 6.9 9.7 22.2 25.6 12.0 22.2 34.5 15.3 7.9 4.4 29.0 26.4 0.4 17.7 2.3 27.7 6.6 8.2 12.2 22.4 9.3 1.9 9.2 137.3 14.7 1.5 12.6 36.0 13.5 15.8 4.1 1.0 0.8 4.4 62.3 8.3 10.1 0.4 67.7 4.0 7.9 1.3 4.4 21.0 0.8 0.1 7.6 27.7 1.3 5.8 4.0 4.1 34.6 2.9 1.6 0.7 5.4 6.1 39.8 0.6 4.8 1.1 31.2 55.5 29.3 2.3 7.7 53.8 8.2 14.3 0.8 16.5 7.8 34.8 11.4 0.2 7.9 36.6 24.2 13.3 37.3 18.3 28.5 14.7 10.9 12.2 17.5 14.1 12.3 6.4 9.9 80.9 12.3 50.6 8.7 12.1 17.1 8.3 8.1 6.4 12.3 7.7 6.4 8.3 7.3 8.5 7.4 9.7 7.9 323.2 471.1 135.1 11.1 34.9 60.5 235.6 83.5 98.4 4.7 43.1 38.0 14.2 50.1 89.0 44.1 25.0 56.3 45.9 103.4 9.8 62.0 8.2 244.8 24.8 148.1 108.3 2.5 18.2 19.8 42.6 37.2 107.6 337.0 64.5 15.7 86.7 21.6 14.7 10.1 11.3 108.4 12.2 29.8 28.9 4.3 7.5 51.4 24.9 34.7 15.4 84.1 64.9 8.0 4.9 69.1 43.6 29.0 34.8 66.1 100.5 26.7 64.4 12.4 26.3 8.8 30.0 2.1 1.1 11.4 20.6 42.8 59.4 37.2 46.6 90.3 NEIL3 "FLJ10858, FPG2, hFPG2, hNEI3, ZGRF3" ENSG00000109674 "Nei like DNA glycosylase 3" Q8TAT5 4 177309874-177362936 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Glycosidase, Hydrolase, Lyase, Multifunctional enzyme" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "bone marrow: 6.6;lymphoid tissue: 23.6" "Cell type enhanced" "Detected in some" "Erythroid cells: 14.7;Granulosa cells: 4.8;Plasma cells: 6.1;Squamous epithelial cells: 4.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HDLM-2: 72.1;HL-60: 79.1;Karpas-707: 99.1;MOLT-4: 80.7" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebellum: 3.3" HPA065761 Enhanced Nucleoplasm NA Yes "Cluster 48: NK-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA065761: AB_2685555" "unprognostic (6.03e-2)" "unprognostic (5.79e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (5.45e-4)" "unprognostic (4.91e-2)" "unprognostic (2.05e-1)" "unprognostic (3.64e-7)" "prognostic unfavorable (1.16e-4)" "unprognostic (6.09e-3)" "unprognostic (7.67e-2)" "unprognostic (6.51e-4)" "unprognostic (2.82e-3)" "unprognostic (0.00e+0)" "unprognostic (3.25e-2)" "unprognostic (8.13e-2)" "unprognostic (2.03e-1)" "unprognostic (1.04e-2)" 0.1 0.0 0.0 1.7 0.0 6.6 0.3 0.0 0.1 0.2 0.0 1.1 1.1 0.1 0.0 1.6 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 3.6 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 1.5 0.0 0.2 0.0 0.0 2.3 1.3 0.5 0.0 0.4 0.6 1.5 0.1 23.6 0.0 0.0 3.5 0.4 0.4 0.0 19.3 15.8 16.4 8.2 1.8 3.3 8.0 23.4 8.6 25.3 14.9 5.8 16.5 21.2 3.4 6.2 25.1 8.8 17.4 9.3 36.6 72.1 11.4 14.7 11.9 15.2 0.5 79.1 9.7 0.3 0.5 26.2 5.6 5.2 9.9 53.9 15.3 99.1 16.7 8.4 80.7 30.2 7.5 5.7 11.5 16.2 11.2 6.8 6.8 2.6 12.8 8.9 11.7 13.4 6.3 7.2 10.9 20.4 4.7 15.2 11.8 7.8 24.0 6.8 4.8 33.5 10.1 27.8 24.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.2 0.1 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.9 0.1 0.4 1.2 0.0 0.2 0.1 0.4 0.0 1.3 0.0 0.0 2.6 1.6 0.5 0.0 0.0 0.1 0.1 0.6 0.3 0.0 14.7 0.1 0.2 3.3 0.9 0.0 0.5 0.0 4.8 0.4 0.0 1.5 0.0 0.1 1.0 0.0 1.3 0.4 0.2 0.0 1.7 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.1 0.7 6.1 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.5 2.7 2.4 4.5 1.3 0.3 1.0 0.5 1.2 0.2 NEURL3 "Lincr, LOC93082, RNF132" ENSG00000163121 "Neuralized E3 ubiquitin protein ligase 3" Q96EH8 2 96497646-96508109 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "kidney: 16.2;pancreas: 25.1;salivary gland: 30.3" "Group enriched" "Detected in many" 4 "Ductal cells: 114.6;Exocrine glandular cells: 36.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 3.8;CAPAN-2: 15.6;GAMG: 5.5;RPMI-8226: 10.1;RT4: 4.7" "Low region specificity" "Detected in some" "Not detected" "Not detected" NA NA "Cluster 25: Pancreas - Digestion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 1: Pancreatic cells - Digestion" "unprognostic (4.97e-2)" "unprognostic (6.07e-2)" "unprognostic (7.22e-2)" "unprognostic (1.42e-2)" "unprognostic (2.49e-2)" "unprognostic (4.35e-2)" "prognostic unfavorable (6.46e-4)" "unprognostic (2.29e-1)" "unprognostic (9.55e-2)" "unprognostic (1.18e-2)" "unprognostic (1.06e-1)" "unprognostic (8.14e-3)" "unprognostic (1.23e-2)" "unprognostic (5.83e-2)" "unprognostic (6.57e-2)" "unprognostic (2.44e-1)" "unprognostic (6.57e-4)" 0.1 0.0 0.8 0.4 0.8 0.3 1.9 0.6 0.9 0.1 0.5 0.7 1.6 0.1 0.1 0.1 0.2 2.1 0.2 0.8 0.7 16.2 2.5 2.5 0.2 0.8 0.7 0.0 25.1 0.0 0.3 0.0 0.8 3.9 0.5 0.1 30.3 2.5 0.1 0.6 2.1 0.0 0.7 0.6 0.5 0.4 0.7 4.8 0.0 0.0 0.3 0.4 0.0 0.9 1.0 0.5 0.0 0.3 0.0 0.0 3.8 0.0 0.4 0.3 0.2 2.3 15.6 0.0 1.2 0.0 5.5 2.3 0.2 0.0 0.0 0.6 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.4 0.0 0.0 10.1 2.1 4.7 0.0 0.0 0.0 1.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.8 0.8 0.6 0.9 0.8 0.7 0.8 0.7 0.8 0.7 0.7 0.9 0.4 0.0 1.5 0.7 0.9 0.0 10.2 0.0 0.0 0.0 7.6 8.3 0.4 11.5 0.6 9.2 0.0 0.3 0.3 6.9 3.9 114.6 0.0 4.9 0.2 1.0 2.4 3.2 0.4 36.5 0.0 0.2 0.0 0.8 0.0 0.1 0.0 0.2 1.1 0.0 0.1 1.4 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 12.2 0.8 0.0 0.0 0.1 17.8 5.2 0.0 0.0 13.2 10.6 5.8 0.0 0.0 0.0 0.0 0.4 0.7 1.9 0.0 0.0 0.0 0.2 1.4 1.2 5.9 NFE2L2 NRF2 ENSG00000116044 "Nuclear factor, erythroid 2 like 2" Q16236 2 177227595-177392697 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002990, CAB020317, HPA043438" Supported Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Plasma membrane" Cytosol "CAB020317: , HPA002990: AB_1079476, HPA043438: AB_2678482" "unprognostic (2.11e-1)" "unprognostic (3.12e-2)" "unprognostic (5.22e-2)" "unprognostic (1.41e-1)" "unprognostic (5.95e-2)" "unprognostic (3.90e-1)" "unprognostic (5.27e-2)" "unprognostic (9.58e-2)" "unprognostic (3.48e-2)" "unprognostic (9.86e-2)" "unprognostic (4.86e-2)" "unprognostic (1.83e-1)" "prognostic favorable (2.26e-4)" "unprognostic (1.97e-2)" "unprognostic (1.61e-1)" "unprognostic (1.26e-1)" "unprognostic (9.77e-3)" 87.0 73.6 64.8 65.4 83.9 58.9 78.3 74.9 86.7 83.2 78.7 83.4 100.1 92.6 97.2 257.0 88.5 97.7 77.6 66.5 71.6 143.5 176.6 88.5 50.4 82.0 77.5 137.3 47.3 60.4 58.4 80.4 84.5 72.7 85.8 68.2 79.7 90.5 64.4 162.3 82.9 91.8 70.4 69.0 176.9 65.2 75.7 68.2 130.4 65.9 93.8 160.7 108.7 91.8 53.1 57.3 52.2 56.4 181.4 190.2 61.7 91.8 124.9 81.4 90.5 75.9 97.9 52.8 93.8 102.8 148.4 96.9 65.1 136.7 111.5 40.8 41.1 65.9 95.9 156.3 231.2 39.3 60.6 134.0 314.5 115.5 169.3 184.4 80.9 39.7 72.7 91.4 111.8 49.8 42.3 101.9 58.8 277.2 58.9 34.0 46.5 54.6 120.9 182.1 69.0 45.0 202.9 64.8 216.6 147.8 49.1 105.0 119.9 80.4 54.5 89.5 54.7 70.1 44.7 43.1 81.6 43.3 159.4 130.6 89.3 55.4 55.2 84.3 62.9 61.8 64.0 57.0 100.4 51.9 101.2 66.8 103.2 68.1 83.0 38.8 66.6 66.0 64.8 83.9 74.9 86.7 66.5 71.6 82.0 77.5 84.5 70.4 75.7 91.8 193.3 157.0 93.5 66.3 143.3 295.8 241.8 448.4 306.7 61.3 90.0 113.7 67.9 117.2 247.0 154.5 16.7 113.2 249.1 120.7 393.2 154.5 81.4 238.1 126.9 139.6 75.6 58.0 25.3 170.8 34.5 206.6 170.7 279.9 212.7 141.5 120.0 93.2 88.1 57.2 26.6 73.5 321.4 111.6 569.9 39.0 287.7 266.0 96.0 88.1 170.6 191.4 55.6 63.8 113.0 128.3 91.8 214.0 118.8 150.5 94.9 85.0 205.9 48.4 39.5 211.8 152.4 66.1 32.1 617.9 315.4 186.2 150.6 153.5 119.6 225.2 NGEF ARHGEF27 ENSG00000066248 "Neuronal guanine nucleotide exchange factor" Q8N5V2 2 232878701-233013256 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 56.2;brain: 129.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 38.0;Excitatory neurons: 105.9;Proximal enterocytes: 66.7" "Cancer enhanced" "Detected in many" "testis cancer: 22.5" "Region enhanced" "Detected in many" "basal ganglia: 129.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 53.9;HDLM-2: 45.3;HeLa: 21.6;PC-3: 57.0;T-47d: 32.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basal ganglia: 167.6;cerebral cortex: 133.8;hippocampal formation: 73.0" HPA008160 Approved Approved "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cytosol" "HPA008160: AB_1854450" "unprognostic (3.92e-1)" "unprognostic (1.78e-1)" "unprognostic (4.12e-3)" "unprognostic (1.66e-1)" "unprognostic (5.25e-2)" "unprognostic (5.46e-2)" "unprognostic (1.15e-1)" "unprognostic (2.39e-3)" "unprognostic (5.41e-3)" "unprognostic (2.58e-1)" "unprognostic (6.94e-3)" "unprognostic (1.24e-1)" "unprognostic (6.16e-2)" "unprognostic (2.31e-1)" "unprognostic (1.10e-1)" "unprognostic (2.80e-2)" "unprognostic (2.74e-1)" 1.1 56.2 16.3 2.2 129.6 0.1 1.9 0.0 59.4 4.1 0.0 14.2 42.7 5.0 4.1 10.3 4.8 3.1 2.2 19.8 0.0 7.0 35.5 0.7 0.2 0.0 0.0 2.0 6.0 11.9 2.7 0.3 0.0 1.8 10.5 1.4 2.0 0.7 0.9 30.3 31.3 6.7 0.0 0.4 10.7 3.7 0.2 0.0 0.9 0.7 0.3 1.8 5.2 29.4 53.9 15.4 0.6 0.2 0.2 8.2 0.9 0.9 0.1 0.4 0.0 0.7 5.2 0.0 15.2 10.9 5.5 6.9 11.6 3.0 0.4 45.3 3.8 0.1 21.6 16.7 0.2 0.0 0.3 0.0 0.2 3.5 0.6 0.2 1.9 0.2 0.2 0.2 0.5 4.0 0.0 0.1 1.3 0.2 57.0 0.0 0.0 0.1 1.0 1.4 1.9 0.4 6.6 3.3 0.1 2.0 32.2 0.4 0.0 0.5 4.5 0.3 1.0 0.5 0.2 0.0 3.8 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.3 129.6 0.0 59.4 19.8 0.0 0.0 0.0 0.0 0.0 0.2 29.4 0.0 0.0 0.0 10.4 0.0 9.9 1.2 1.2 2.8 0.3 2.1 1.4 2.4 4.3 0.5 0.0 0.0 0.1 0.0 38.0 0.0 3.9 0.7 9.1 0.9 0.4 4.9 0.0 105.9 10.5 0.3 0.7 17.3 2.0 0.0 0.3 0.4 20.4 0.1 1.7 12.8 14.6 0.0 0.3 0.6 2.0 0.0 0.3 1.8 6.5 0.0 5.5 0.0 4.5 6.0 12.1 23.5 1.2 0.1 0.5 66.7 9.8 2.5 0.2 0.0 0.2 0.3 1.1 0.8 3.8 7.5 0.0 0.2 0.5 20.2 1.1 NHLH2 "bHLHa34, HEN2, NSCL2" ENSG00000177551 "Nescient helix-loop-helix 2" Q02577 1 115836377-115843917 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 7.4;esophagus: 2.3;retina: 2.1;skin 1: 3.3" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 14.8;Oligodendrocyte precursor cells: 4.5;Oligodendrocytes: 7.9;Spermatocytes: 5.1;Squamous epithelial cells: 7.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "SCLC-21H: 58.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA055238 Uncertain Approved "Nucleoplasm,Nuclear bodies" Yes NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 37: Myocytes - Muscle contraction" "Nuclear bodies" Nucleoplasm "HPA055238: AB_2682752" "unprognostic (2.20e-2)" "unprognostic (2.28e-1)" "unprognostic (1.97e-1)" "unprognostic (1.82e-1)" "unprognostic (2.17e-1)" "unprognostic (1.58e-1)" "unprognostic (4.82e-2)" "unprognostic (1.11e-2)" "unprognostic (5.26e-2)" "unprognostic (9.55e-2)" "unprognostic (2.80e-3)" "unprognostic (1.53e-1)" "unprognostic (3.09e-1)" "unprognostic (2.25e-1)" 0.0 0.0 2.0 0.0 1.4 0.0 0.1 5.9 2.1 0.3 0.2 0.0 0.0 0.0 0.3 2.3 0.0 0.0 0.0 3.2 4.0 0.0 0.0 0.2 0.0 3.8 5.1 0.0 0.0 0.0 0.2 0.0 7.4 0.2 0.0 2.1 0.4 0.1 0.2 3.3 0.0 0.0 2.5 0.0 0.2 0.4 6.7 0.0 0.0 0.0 0.0 0.0 0.7 3.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 58.4 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 1.4 5.9 2.1 3.2 4.0 3.8 5.1 7.4 2.5 6.7 3.0 0.0 0.0 0.0 0.3 0.0 2.8 2.8 3.3 14.8 3.9 0.0 0.6 3.4 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.2 1.8 0.0 2.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.3 0.0 4.5 7.9 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.4 0.0 3.5 0.3 5.1 3.4 7.0 2.3 0.0 0.0 0.0 0.0 0.4 NKPD1 FLJ33600 ENSG00000179846 "NTPase KAP family P-loop domain containing 1" Q17RQ9 19 45149750-45160815 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "skin 1: 15.9" "Cell type enhanced" "Detected in some" "Horizontal cells: 5.0;Spermatocytes: 2.4;Suprabasal keratinocytes: 1.3" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTCEpi: 1.4;SiHa: 1.2;U-266/70: 2.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA043339 Uncertain NA NA "Cluster 61: Skin - Cornification" "Cluster 29: U-266 - Adaptive immune response" "Cluster 62: Horizontal cells - Visual perception" "HPA043339: AB_10962493" "unprognostic (3.98e-2)" "unprognostic (5.94e-2)" "unprognostic (2.14e-1)" "unprognostic (8.30e-4)" "unprognostic (2.23e-1)" "unprognostic (4.60e-2)" "unprognostic (2.41e-3)" "unprognostic (2.01e-2)" "unprognostic (2.60e-1)" "unprognostic (2.35e-2)" "unprognostic (7.73e-4)" "unprognostic (1.30e-1)" "unprognostic (2.77e-5)" "unprognostic (1.00e-1)" "unprognostic (1.26e-1)" "unprognostic (8.90e-2)" "unprognostic (2.13e-1)" 0.1 0.1 0.4 0.0 0.1 0.2 0.5 0.2 0.4 1.3 0.0 0.0 0.0 0.1 0.2 1.0 0.3 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.4 0.0 0.2 0.1 0.1 0.5 0.0 0.5 0.8 0.0 0.3 0.5 0.5 0.1 15.9 0.1 0.0 0.0 0.2 0.0 1.7 0.0 0.0 0.3 0.0 0.0 0.2 3.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.4 0.3 0.2 0.1 0.6 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.1 1.2 0.7 0.0 0.1 0.5 0.1 0.0 0.0 0.0 0.0 0.0 2.9 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.2 0.4 0.1 0.2 0.4 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.1 0.4 0.0 0.6 0.9 0.2 1.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.4 0.1 0.0 0.0 0.8 0.2 0.0 0.1 0.0 0.7 0.0 0.2 0.0 0.0 0.1 5.0 0.9 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 1.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.4 0.2 0.5 1.3 0.1 0.0 0.2 0.0 0.1 NKRF "ITBA4, NRF" ENSG00000186416 "NFKB repressing factor" O15226 X 119588337-119606443 "Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 33.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001476 Supported Nucleoplasm,Nucleoli NA NA "Cluster 46: Basophils - DNA binding" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 41: Macrophages - Immune response" Nucleoli Nucleoplasm "HPA001476: AB_1079488" "unprognostic (6.12e-3)" "unprognostic (7.58e-2)" "unprognostic (8.10e-2)" "unprognostic (2.39e-1)" "unprognostic (9.92e-2)" "unprognostic (4.74e-3)" "prognostic unfavorable (4.92e-5)" "unprognostic (2.47e-1)" "unprognostic (1.20e-1)" "unprognostic (2.65e-1)" "unprognostic (1.33e-2)" "unprognostic (9.56e-3)" "unprognostic (2.62e-2)" "unprognostic (5.06e-2)" "unprognostic (1.04e-2)" "unprognostic (2.20e-3)" "unprognostic (3.08e-3)" 4.4 6.5 11.3 5.7 11.8 6.9 5.4 9.6 16.9 4.2 7.3 3.7 4.1 3.9 4.0 5.6 4.4 3.5 4.1 11.5 13.1 6.1 6.0 4.1 8.7 11.2 10.1 6.1 3.8 5.2 5.5 6.5 11.5 4.1 3.5 5.3 4.0 3.5 5.5 6.2 4.3 4.0 9.4 5.9 4.1 1.9 11.4 9.5 4.6 4.6 8.4 6.3 4.3 10.6 17.9 18.3 10.4 11.3 8.7 8.5 15.5 10.7 8.5 14.1 15.0 19.8 15.3 31.8 18.4 9.2 12.1 20.4 43.8 16.4 17.2 16.4 28.9 16.8 20.3 12.9 8.3 33.5 11.8 9.5 13.2 16.3 19.2 9.6 14.1 15.3 18.5 12.6 12.5 27.6 20.8 25.2 23.1 26.2 19.9 16.5 15.2 32.7 18.8 12.7 16.7 14.2 15.2 23.1 16.5 10.6 9.7 20.0 12.2 8.7 9.5 19.3 27.1 10.5 14.1 32.9 9.3 36.3 10.1 1.1 0.5 0.7 1.0 0.8 1.1 1.3 1.2 1.3 0.6 1.2 1.9 1.6 0.1 0.5 0.3 0.9 1.8 0.8 11.3 11.8 9.6 16.9 11.5 13.1 11.2 10.1 11.5 9.4 11.4 10.6 5.4 6.4 8.9 5.9 11.1 19.4 10.4 4.1 6.8 13.3 6.1 6.9 4.5 8.6 3.1 5.5 27.1 14.4 8.5 3.0 1.9 4.2 0.1 6.1 7.4 7.0 10.7 2.5 20.6 3.6 14.3 6.1 3.1 8.1 14.7 6.6 3.3 3.9 6.4 8.4 20.6 4.4 10.2 7.5 33.1 0.6 7.8 11.6 5.4 7.5 5.6 4.4 1.0 9.0 9.2 4.1 1.9 6.8 5.2 10.7 3.6 4.4 3.9 7.9 0.0 10.1 7.2 1.7 1.9 6.9 25.7 14.9 15.7 6.9 7.4 9.5 NLRP10 "CLR11.1, NALP10, NOD8, PAN5, Pynod" ENSG00000182261 "NLR family pyrin domain containing 10" Q86W26 11 7957537-7965426 "Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity, Inflammatory response, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "skin 1: 6.3" "Cell type enriched" "Detected in single" 5 "Microglial cells: 1.0" "Cancer enhanced" "Detected in single" "head and neck cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 22.3;BJ: 5.9;HBF TERT88: 7.7;LHCN-M2: 3.7" "Region enhanced" "Detected in some" "olfactory bulb: 2.1" "HPA039498, HPA040101" Uncertain Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 61: Skin - Cornification" "Cluster 10: BJ & FHDF - ECM organization" Nucleoplasm "Nuclear membrane" "HPA039498: AB_10795679, HPA040101: AB_10795519" "unprognostic (4.06e-1)" "unprognostic (4.34e-1)" "unprognostic (9.78e-3)" "unprognostic (2.87e-2)" 0.0 0.0 0.1 0.0 0.0 0.1 1.4 0.2 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.2 0.0 0.0 0.1 6.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 22.3 0.0 0.0 0.1 0.0 0.3 0.1 5.9 2.8 1.3 2.8 0.1 0.0 0.0 0.1 1.8 0.0 0.0 0.0 1.0 7.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.3 0.1 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.9 2.8 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 NMU ENSG00000109255 "Neuromedin U" P48645 4 55595229-55636698 "Predicted secreted proteins" Neuropeptide "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 100.2;skin 1: 38.5;vagina: 30.7" "Group enriched" "Detected in many" 4 "Squamous epithelial cells: 212.4;Suprabasal keratinocytes: 73.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 10 "MAIT T-cell: 3.6;memory CD4 T-cell: 1.1" "Lineage enriched" "Detected in single" 37 "T-cells: 3.6" "Cell line enhanced" "Detected in many" "Daudi: 90.2;HaCaT: 382.6;K-562: 311.3;Karpas-707: 135.7" "Group enriched" "Detected in some" 8 "hypothalamus: 1.1;pons and medulla: 4.5" "Low region specificity" "Detected in some" HPA025926 Uncertain "Secreted in other tissues" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA025926: AB_1854539" "unprognostic (4.42e-2)" "unprognostic (1.00e-1)" "unprognostic (5.83e-2)" "prognostic unfavorable (2.60e-5)" "unprognostic (1.08e-1)" "unprognostic (5.19e-2)" "unprognostic (7.12e-2)" "unprognostic (7.29e-3)" "unprognostic (9.36e-2)" "unprognostic (1.12e-1)" "unprognostic (1.03e-2)" "unprognostic (3.00e-1)" "prognostic unfavorable (4.07e-10)" "unprognostic (1.61e-1)" "unprognostic (5.66e-2)" "unprognostic (2.54e-2)" "unprognostic (5.55e-2)" 0.1 0.3 0.4 0.7 0.5 9.7 1.5 0.6 1.1 12.3 0.0 1.4 0.8 0.1 0.0 100.2 0.2 0.0 0.2 0.3 2.8 0.2 0.0 0.8 0.5 1.1 2.6 0.1 0.1 0.0 2.3 0.8 0.8 0.2 0.8 0.1 14.3 0.2 0.1 38.5 1.4 0.2 3.0 0.1 4.0 2.2 6.8 1.7 2.5 0.0 7.7 0.1 30.7 0.4 41.3 0.3 22.1 5.6 0.0 0.0 0.0 0.0 0.0 2.9 7.8 0.3 61.5 90.2 8.6 0.0 8.5 382.6 46.1 3.3 2.3 5.6 25.1 0.6 36.0 0.0 0.0 0.0 0.3 0.0 4.2 0.0 3.0 10.0 0.4 6.4 311.3 135.7 0.3 9.9 1.2 0.2 11.7 7.5 11.4 0.2 0.0 0.5 1.9 0.4 19.5 49.0 30.9 0.8 0.1 4.2 20.9 0.1 2.7 0.2 27.5 0.3 54.5 39.1 0.3 0.0 18.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 3.6 0.0 1.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.6 1.1 0.3 2.8 1.1 2.6 0.8 3.0 6.8 0.4 0.0 0.0 2.3 0.0 0.6 16.3 0.6 16.2 4.0 0.2 0.9 1.3 0.1 0.0 8.0 0.0 0.0 2.0 0.0 0.6 0.0 0.1 0.4 3.9 0.3 0.7 0.0 14.5 0.2 0.2 0.1 4.4 29.6 5.8 1.3 0.9 0.0 0.1 0.3 0.0 17.2 0.8 20.3 0.0 1.6 0.3 0.0 0.2 3.6 0.0 0.1 2.0 0.0 1.0 0.2 2.4 0.2 0.0 1.2 0.4 0.0 0.0 7.0 0.0 0.0 0.0 1.2 5.8 10.0 212.4 73.6 0.1 0.7 0.2 2.6 12.0 NPDC1 "CAB-, CAB1, DKFZp586J0523" ENSG00000107281 "Neural proliferation, differentiation and control 1" Q9NQX5 9 137039463-137046179 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 397.0;Endothelial cells: 307.2;Enteroendocrine cells: 281.6;Hepatic stellate cells: 406.2;Intestinal goblet cells: 589.1" "Cancer enhanced" "Detected in all" "prostate cancer: 146.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 12.3;MAIT T-cell: 14.7;memory CD4 T-cell: 19.0;memory CD8 T-cell: 18.9;T-reg: 15.9" "Lineage enriched" "Detected in many" 5 "T-cells: 19.0" "Cell line enhanced" "Detected in many" "MCF7: 138.4;RPMI-8226: 132.8;T-47d: 140.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008189 Approved Approved Nucleoplasm,Cytosol NA NA 240000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 27: Mucus-secreting cells - Mucin production" Nucleoplasm Cytosol "HPA008189: AB_1854584" "unprognostic (6.94e-2)" "unprognostic (1.07e-1)" "prognostic unfavorable (2.01e-5)" "prognostic favorable (6.19e-5)" "unprognostic (2.06e-1)" "unprognostic (4.83e-3)" "unprognostic (1.24e-1)" "unprognostic (4.35e-2)" "unprognostic (8.65e-2)" "unprognostic (1.53e-1)" "prognostic favorable (3.18e-4)" "unprognostic (2.40e-1)" "unprognostic (2.65e-2)" "unprognostic (1.23e-2)" "unprognostic (2.35e-1)" "unprognostic (4.20e-2)" "unprognostic (8.84e-2)" 129.5 45.7 140.8 12.2 128.1 3.4 133.0 110.6 181.3 130.5 55.0 93.1 23.4 121.6 4.3 53.7 148.6 24.9 149.1 143.3 143.1 75.9 23.7 115.4 13.0 138.9 142.3 68.2 81.2 23.0 266.0 21.1 131.3 260.5 13.4 9.2 137.4 35.1 34.0 56.4 72.1 16.9 120.7 145.2 126.2 35.3 142.9 2.9 68.4 12.4 3.9 97.9 90.5 114.7 33.6 41.9 10.1 67.1 23.7 23.8 2.8 68.7 23.0 16.9 6.7 17.1 18.5 30.3 50.7 28.6 4.6 122.4 8.6 20.5 1.6 25.0 40.4 13.6 123.7 12.9 33.3 11.9 0.3 16.5 31.9 8.7 17.9 43.1 43.6 13.2 0.7 0.8 3.5 138.4 1.0 1.1 21.1 111.0 68.1 19.9 0.0 132.8 28.6 22.7 77.2 50.0 18.4 65.3 46.5 3.6 140.1 17.9 73.9 12.4 21.6 84.1 21.0 0.1 0.4 1.4 17.7 1.2 10.5 0.0 0.6 0.9 12.3 0.1 14.7 0.1 19.0 18.9 1.1 0.0 0.5 3.1 0.0 0.2 0.1 3.4 15.9 3.3 140.8 128.1 110.6 181.3 143.3 143.1 138.9 142.3 131.3 120.7 142.9 114.7 397.0 0.0 7.7 64.3 3.4 23.6 77.6 15.0 31.3 97.5 174.0 139.7 18.3 71.4 19.8 29.5 16.7 1.1 5.5 122.2 0.0 52.5 1.8 39.0 27.7 307.2 281.6 19.3 71.7 66.0 1.3 61.2 153.9 101.3 0.0 9.2 406.2 1.9 22.2 62.2 64.7 589.1 18.3 21.0 20.0 6.9 161.2 6.6 30.2 37.5 3.0 38.5 1.0 38.2 39.0 33.0 106.0 145.6 1.4 234.9 37.5 0.7 7.5 62.0 39.5 23.9 38.9 2.8 19.0 15.9 23.7 1.8 12.3 9.1 98.1 103.1 NR1D1 "ear-1, hRev, Rev-ErbAalpha, REVERBA, REVERBalpha, THRA1, THRAL" ENSG00000126368 "Nuclear receptor subfamily 1 group D member 1" P20393 17 40092793-40100589 "Metabolic proteins, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding, Receptor, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 325.5" "Cell type enhanced" "Detected in all" "Squamous epithelial cells: 95.5;Suprabasal keratinocytes: 81.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 18.5" "Group enriched" "Detected in many" 6 "monocytes: 5.5;T-cells: 18.5" "Cell line enhanced" "Detected in all" "Karpas-707: 60.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007935 Uncertain Supported "Nuclear bodies" NA Yes "Cluster 16: MAIT-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 2: Karpas-707 - Immune response" "Cluster 61: Squamous epithelial cells - Keratinization" "Nuclear bodies" "HPA007935: AB_10601277" "unprognostic (1.38e-2)" "unprognostic (3.46e-2)" "prognostic unfavorable (1.94e-4)" "unprognostic (2.53e-1)" "unprognostic (2.24e-2)" "unprognostic (1.05e-1)" "unprognostic (4.50e-2)" "unprognostic (1.03e-1)" "prognostic favorable (1.36e-4)" "unprognostic (1.93e-3)" "unprognostic (9.93e-3)" "unprognostic (2.73e-1)" "unprognostic (9.15e-3)" "unprognostic (4.54e-3)" "unprognostic (2.49e-1)" "unprognostic (3.09e-1)" "unprognostic (1.34e-1)" 72.3 53.7 23.5 6.3 27.0 5.4 63.1 52.9 49.7 109.6 10.6 53.3 14.3 35.8 4.5 42.5 27.7 7.1 60.8 24.9 17.2 38.0 43.2 49.2 9.3 18.1 20.9 71.3 24.3 9.0 32.0 6.0 15.9 40.5 4.0 50.4 52.9 16.3 99.0 325.5 23.0 7.5 12.9 11.6 31.5 12.5 34.0 6.3 32.1 38.1 5.4 42.5 96.5 25.2 5.5 7.8 1.6 6.2 9.0 6.2 2.2 11.9 19.5 3.9 4.9 5.1 19.5 6.7 6.9 13.8 12.9 15.4 4.1 18.0 2.9 5.6 4.1 4.8 7.9 13.5 14.6 7.2 6.9 13.5 12.8 13.3 28.2 12.6 4.9 7.7 7.2 60.6 3.8 3.8 10.7 6.1 3.0 10.8 12.3 7.5 2.2 20.7 5.4 4.9 5.1 2.9 7.6 9.7 12.4 2.7 4.6 5.8 4.7 17.2 16.7 14.1 9.5 21.5 35.7 2.6 23.4 4.0 13.6 0.0 0.5 0.0 4.4 2.0 18.5 1.7 5.5 6.4 1.1 2.1 4.8 3.5 0.2 1.0 5.5 1.4 8.0 1.8 23.5 27.0 52.9 49.7 24.9 17.2 18.1 20.9 15.9 12.9 34.0 25.2 16.4 3.2 2.0 17.3 5.7 64.5 47.5 20.5 67.2 71.4 9.4 15.1 5.7 8.6 11.9 1.8 4.2 2.6 4.9 26.0 7.9 16.1 2.3 25.4 30.6 18.6 8.3 3.6 7.1 11.8 1.2 26.5 31.1 64.2 2.5 2.7 6.8 31.8 2.5 42.1 6.2 7.2 8.2 3.4 19.4 1.5 21.8 7.7 19.6 8.4 1.2 39.0 5.2 5.0 1.2 26.0 14.7 38.7 10.5 35.4 58.8 7.9 5.0 29.7 6.6 9.6 19.4 2.0 11.1 95.5 81.1 2.3 11.9 13.7 6.0 28.7 NR5A2 "B1F2, FTF, FTZ-F1, FTZ-F1beta, hB1F, hB1F-2, LRH-1, LRH1" ENSG00000116833 "Nuclear receptor subfamily 5 group A member 2" O00482 1 200027614-200177420 "Nuclear receptors, Predicted intracellular proteins, Transcription factors, Transporters" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 17.8;liver: 38.6;pancreas: 61.1" "Cell type enriched" "Detected in many" 5 "Granulosa cells: 276.2" "Cancer enhanced" "Detected in many" "liver cancer: 6.6" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 4 "basophil: 3.2;neutrophil: 1.5" "Lineage enriched" "Detected in single" 6 "granulocytes: 3.2" "Cell line enhanced" "Detected in some" "A549: 25.0;CACO-2: 6.2;HAP1: 14.9;HMC-1: 6.4;HUVEC TERT2: 20.4" "Region enhanced" "Detected in single" "hypothalamus: 1.2" "Not detected" "Not detected" "HPA005455, HPA017067" Approved Uncertain "Nuclear speckles" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 40: Granulosa cells - Unknown function" "Nuclear speckles" "HPA005455: AB_1078140, HPA017067: AB_1844767" "unprognostic (7.47e-2)" "unprognostic (1.43e-1)" "unprognostic (5.84e-2)" "unprognostic (1.56e-2)" "unprognostic (1.19e-2)" "unprognostic (6.63e-3)" "unprognostic (4.46e-2)" "unprognostic (3.78e-2)" "unprognostic (3.34e-1)" "unprognostic (8.50e-2)" "unprognostic (4.64e-2)" "unprognostic (1.44e-1)" "unprognostic (1.00e-7)" "unprognostic (5.48e-2)" "unprognostic (5.07e-2)" "unprognostic (9.23e-2)" "unprognostic (1.37e-1)" 5.4 0.4 0.5 2.6 0.2 0.9 3.7 0.5 0.3 3.4 0.2 11.9 17.4 3.3 1.4 0.9 2.2 8.0 1.0 0.3 2.8 0.7 38.6 2.7 2.1 0.7 0.6 1.0 61.1 0.4 0.1 0.4 0.8 1.6 13.1 0.2 0.5 0.8 1.1 1.1 17.8 4.3 0.4 0.2 1.3 0.8 0.8 0.5 0.9 0.7 1.4 1.8 1.2 0.7 0.0 25.0 0.0 0.1 0.0 0.2 0.6 0.0 0.4 0.0 0.0 6.2 0.1 0.0 0.0 0.0 0.7 0.7 14.9 0.0 0.0 3.3 1.1 0.0 0.3 2.7 0.5 0.1 6.4 0.1 0.0 0.0 0.1 0.0 20.4 0.1 0.0 0.3 0.0 0.6 0.0 0.4 0.9 0.0 0.3 0.4 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.1 1.7 4.7 0.3 0.1 1.0 0.2 0.1 0.2 3.4 2.3 2.6 0.3 0.2 0.1 3.2 0.4 0.4 0.2 0.2 0.2 0.3 0.3 0.3 0.1 0.4 0.4 0.3 1.5 0.5 0.2 0.5 0.4 0.1 0.5 0.2 0.5 0.3 0.3 2.8 0.7 0.6 0.8 0.4 0.8 0.7 23.7 0.0 1.7 0.3 0.2 1.9 0.1 0.0 0.0 0.2 0.2 0.0 9.9 32.9 0.0 0.0 0.0 0.0 0.3 37.5 0.0 38.2 0.4 0.3 0.3 32.4 4.9 2.7 0.4 54.5 0.0 0.8 0.0 0.2 13.3 276.2 38.6 38.5 0.1 0.0 0.6 13.8 0.0 4.9 1.5 0.3 0.6 0.6 0.0 0.0 3.1 0.0 0.0 1.0 0.3 22.0 21.8 0.0 1.2 0.3 49.9 0.0 0.8 0.3 0.0 0.5 6.1 0.1 0.1 0.0 1.4 0.0 0.3 0.1 32.3 0.2 NSFL1C "dJ776F14.1, p47, UBX1, UBXD10, UBXN2C" ENSG00000088833 "NSFL1 cofactor" Q9UNZ2 20 1442162-1473842 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047108, HPA050628" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" No No 1900000 "Cluster 5: Granulocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Plasma membrane, Cytosol" "HPA047108: AB_2679935, HPA050628: AB_2681194" "unprognostic (7.55e-2)" "unprognostic (5.26e-2)" "unprognostic (2.51e-2)" "unprognostic (2.47e-1)" "unprognostic (5.96e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (1.29e-4)" "unprognostic (1.10e-2)" "unprognostic (1.59e-1)" "unprognostic (4.67e-2)" "unprognostic (2.58e-1)" "unprognostic (4.97e-2)" "unprognostic (6.90e-2)" "unprognostic (5.46e-2)" "unprognostic (1.54e-1)" "unprognostic (7.44e-2)" "unprognostic (7.50e-3)" 22.8 37.7 38.3 13.5 39.5 27.8 21.5 37.0 45.9 23.2 41.6 23.0 14.9 22.5 26.8 28.5 26.1 13.5 29.1 39.7 38.6 21.4 26.3 18.0 15.2 39.0 39.0 25.7 15.5 23.9 14.1 21.1 39.8 20.9 18.4 22.6 19.3 26.4 69.0 36.6 17.6 22.9 36.4 19.8 18.0 14.8 38.6 21.0 20.0 43.3 18.6 22.4 21.6 39.7 55.6 64.4 35.9 32.0 30.5 31.4 28.7 21.0 41.8 57.7 41.3 53.9 43.1 31.6 16.6 47.8 47.2 50.4 25.9 70.3 40.8 12.3 25.1 29.8 10.3 61.4 33.8 30.7 16.4 23.5 33.3 55.3 20.3 30.8 46.8 23.4 42.5 26.5 36.2 29.1 31.4 54.7 40.7 42.5 65.4 14.7 41.1 29.8 68.6 37.1 20.5 23.4 29.6 59.8 26.7 18.8 36.5 22.0 37.8 38.7 29.4 23.9 40.2 21.9 41.8 24.7 28.9 43.0 29.3 31.4 21.3 80.3 20.0 26.6 19.7 35.0 21.2 19.5 29.7 36.0 23.4 20.7 69.1 16.7 28.1 23.1 28.2 25.5 38.3 39.5 37.0 45.9 39.7 38.6 39.0 39.0 39.8 36.4 38.6 39.7 34.6 22.4 23.2 17.3 36.1 89.2 63.5 106.3 44.3 60.2 28.6 26.0 35.4 24.3 57.8 31.3 22.9 150.7 29.7 68.2 56.7 104.7 23.0 51.0 29.6 44.3 43.6 41.0 24.0 94.5 146.0 41.1 30.5 54.9 40.5 49.1 31.1 42.2 81.1 70.7 24.8 42.5 61.1 43.7 43.6 38.8 39.1 43.8 42.7 14.0 52.9 61.7 32.0 17.6 31.2 123.4 65.7 46.3 41.8 76.0 66.4 73.8 43.2 44.5 78.9 44.2 64.7 106.1 103.2 55.1 75.7 151.6 31.6 48.9 44.0 88.5 NUDT19 RP2 ENSG00000213965 "Nudix hydrolase 19" A8MXV4 19 32691961-32713796 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042761 Approved Nucleoplasm,Nucleoli,Cytosol No No "Cluster 49: Eosinophils - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 32: U-937 - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Nucleoli, Cytosol" "HPA042761: " "unprognostic (1.20e-1)" "unprognostic (2.90e-1)" "unprognostic (2.35e-3)" "unprognostic (6.61e-3)" "unprognostic (2.62e-2)" "unprognostic (2.44e-1)" "unprognostic (6.18e-3)" "unprognostic (1.97e-1)" "unprognostic (3.14e-2)" "unprognostic (2.19e-1)" "unprognostic (2.99e-1)" "unprognostic (1.85e-1)" "unprognostic (1.47e-1)" "unprognostic (2.64e-2)" "unprognostic (2.81e-1)" "unprognostic (1.23e-1)" "prognostic favorable (1.35e-4)" 5.1 11.7 4.0 4.1 4.1 8.4 4.6 3.9 4.5 3.9 9.4 6.9 7.1 3.6 5.4 11.1 3.6 2.9 10.6 4.1 5.1 6.3 6.9 6.4 5.8 4.6 4.3 3.7 8.4 7.1 4.0 4.5 4.8 7.5 7.3 8.3 6.9 3.5 23.9 8.9 6.2 4.3 4.3 5.2 8.1 2.8 4.6 3.1 3.6 13.0 5.1 6.3 5.6 4.6 21.5 24.7 2.7 24.0 8.1 10.5 0.2 11.9 4.4 8.7 8.2 14.0 11.6 0.1 14.0 13.8 6.7 13.7 16.7 13.9 11.4 24.8 10.0 27.7 9.3 5.0 11.2 20.9 8.2 8.5 18.1 7.4 17.8 10.1 13.0 4.2 21.6 15.3 15.9 14.3 0.1 19.3 2.9 5.9 11.5 0.1 5.2 12.1 14.4 15.7 10.7 15.4 21.2 17.7 15.9 4.7 9.8 25.4 10.4 11.9 7.7 12.0 21.5 17.8 16.3 6.9 14.4 20.0 11.2 11.1 26.5 15.4 18.2 36.7 20.0 13.0 18.9 22.6 19.5 9.4 14.9 20.4 5.1 32.2 42.4 15.9 23.6 11.9 4.0 4.1 3.9 4.5 4.1 5.1 4.6 4.3 4.8 4.3 4.6 4.6 5.9 12.8 14.5 7.5 6.4 21.9 9.4 4.6 8.0 14.5 12.0 6.6 22.8 2.8 6.2 7.3 12.5 11.0 9.1 10.6 27.4 2.9 7.7 8.5 9.3 7.3 12.1 10.3 5.9 11.5 11.5 6.6 3.1 10.7 1.3 11.3 13.2 12.5 14.3 3.3 6.7 12.7 8.2 17.6 11.6 3.7 4.1 10.2 12.4 4.7 10.7 4.6 4.1 6.6 7.4 12.0 13.1 9.4 4.1 12.0 15.7 18.8 6.5 30.4 0.0 6.9 7.4 1.6 2.2 9.9 31.5 7.8 9.1 22.3 18.4 10.6 OBP2A "hOBPIIa, LCN13, OBP" ENSG00000122136 "Odorant binding protein 2A" Q9NY56 9 135546126-135549969 "Predicted secreted proteins" "Olfaction, Sensory transduction, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "fallopian tube: 24.9" "Cell type enhanced" "Detected in some" "Breast glandular cells: 2.4;Breast myoepithelial cells: 3.4;Late spermatids: 1.8;Leydig cells: 1.5;Melanocytes: 1.8" "Cancer enriched" "Detected in some" 6 "ovarian cancer: 18.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "U-266/70: 1.6;U-266/84: 6.4" HPA055955 Uncertain "Secreted in other tissues" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 16: U-266 - Nucleosome" "Cluster 44: Endometrium - Transcription" "HPA055955: AB_2682985" "unprognostic (2.30e-1)" "unprognostic (3.68e-1)" "unprognostic (4.63e-1)" "unprognostic (1.66e-2)" "unprognostic (2.17e-1)" "unprognostic (3.20e-1)" "unprognostic (2.75e-1)" "unprognostic (7.65e-2)" "unprognostic (2.23e-2)" "unprognostic (8.27e-2)" "unprognostic (1.91e-1)" "unprognostic (6.83e-11)" "unprognostic (5.17e-2)" "unprognostic (3.61e-1)" "unprognostic (1.26e-1)" "unprognostic (3.84e-1)" 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 24.9 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.3 0.0 0.0 0.7 0.7 0.1 0.0 0.0 0.0 0.1 0.1 0.0 2.0 0.0 0.0 0.0 0.1 0.0 6.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 2.4 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.5 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.1 OIP5 "CT86, hMIS18beta, MIS18B" ENSG00000104147 "Opa interacting protein 5" O43482 15 41309273-41332591 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 10.3;skeletal muscle: 10.3;testis: 20.9" "Cell type enhanced" "Detected in many" "Erythroid cells: 45.9;Extravillous trophoblasts: 24.0;Spermatocytes: 110.6;Spermatogonia: 56.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA052271, HPA059602" Enhanced Supported "Nuclear speckles,Vesicles" NA Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear speckles" Vesicles "HPA052271: AB_2681780, HPA059602: AB_2684079" "unprognostic (5.17e-2)" "unprognostic (7.26e-2)" "unprognostic (3.07e-1)" "unprognostic (1.59e-2)" "unprognostic (6.94e-2)" "unprognostic (6.58e-2)" "prognostic unfavorable (1.79e-4)" "prognostic unfavorable (2.26e-4)" "unprognostic (2.71e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (9.34e-5)" "unprognostic (5.51e-2)" "unprognostic (0.00e+0)" "unprognostic (3.84e-2)" "unprognostic (2.02e-1)" "unprognostic (5.75e-2)" "unprognostic (2.86e-2)" 0.6 1.7 0.1 3.3 0.2 10.3 1.2 1.2 0.4 0.9 0.2 4.1 3.5 0.8 0.3 3.8 0.4 0.6 1.5 0.2 0.2 0.3 1.2 0.5 5.8 0.2 0.4 1.5 0.3 0.1 0.1 2.3 0.4 0.5 3.9 0.7 0.8 0.6 10.3 3.3 3.9 1.1 0.1 1.7 1.5 20.9 0.2 9.1 0.4 0.8 5.2 0.7 1.3 0.5 33.7 17.8 34.3 24.9 1.7 2.1 32.4 20.0 9.3 24.5 26.1 31.8 16.2 19.8 17.0 7.7 37.8 51.0 35.7 16.1 19.2 42.4 40.1 42.4 49.8 33.6 0.4 46.5 22.1 0.7 3.2 13.8 14.5 5.2 21.1 40.8 59.4 37.3 16.5 16.3 27.1 34.8 30.9 50.4 37.9 32.9 28.4 30.5 11.1 15.4 53.7 17.5 33.7 34.3 9.6 13.7 33.7 26.3 10.0 24.5 37.3 24.6 36.6 17.0 83.2 71.1 7.1 56.5 35.9 0.0 0.4 0.5 0.2 0.7 0.8 1.0 0.7 0.8 0.7 1.2 1.3 0.8 0.0 1.2 0.4 4.1 3.1 0.8 0.1 0.2 1.2 0.4 0.2 0.2 0.2 0.4 0.4 0.1 0.2 0.5 0.2 0.0 0.5 1.0 2.7 4.1 0.9 3.6 1.2 0.0 1.1 2.2 0.2 0.0 1.8 0.0 0.0 15.0 1.7 2.3 0.0 0.4 12.0 1.9 0.6 0.9 0.0 45.9 2.2 0.4 24.0 1.7 5.1 1.1 1.3 5.2 0.0 0.8 7.5 0.0 2.1 3.0 8.2 2.2 1.8 10.8 0.9 1.2 0.0 0.0 0.6 1.1 2.1 1.5 2.5 0.2 0.5 1.2 10.9 0.4 0.9 0.3 0.0 0.3 6.6 1.0 1.1 110.6 56.8 8.3 2.4 3.8 1.2 2.1 7.6 0.9 OLFML3 "HNOEL-iso, OLF44" ENSG00000116774 "Olfactomedin like 3" Q9NRN5 1 113979391-114035572 "Predicted intracellular proteins, Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 136.6;Fibroblasts: 246.9;Leydig cells: 73.3;Theca cells: 126.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "myeloid DC: 2.1" "Lineage enriched" "Detected in single" 12 "dendritic cells: 2.1" "Cell line enhanced" "Detected in many" "ASC diff: 577.3;ASC TERT1: 312.6;BJ hTERT+: 374.8;HSkMC: 581.6;LHCN-M2: 602.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027991 Supported Vesicles "Secreted to extracellular matrix" NA NA 3000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Vesicles "HPA027991: AB_2732440" "unprognostic (1.04e-1)" "unprognostic (8.06e-2)" "unprognostic (1.87e-1)" "unprognostic (1.50e-2)" "unprognostic (1.41e-1)" "unprognostic (1.50e-1)" "unprognostic (2.02e-1)" "unprognostic (3.72e-1)" "unprognostic (1.67e-1)" "unprognostic (3.04e-2)" "unprognostic (1.43e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (3.45e-5)" "unprognostic (6.80e-3)" "unprognostic (1.88e-1)" "unprognostic (2.61e-1)" "unprognostic (4.41e-3)" 85.6 42.6 5.7 24.9 7.4 0.9 89.7 7.2 12.4 170.6 8.2 71.9 15.1 124.7 42.6 26.6 96.3 95.0 56.6 5.4 6.7 34.1 36.3 55.4 12.0 9.8 7.7 177.4 35.2 9.9 17.9 111.8 8.6 42.9 34.5 0.2 16.7 73.8 10.3 37.6 32.3 94.6 9.2 9.9 48.4 9.3 9.7 8.9 21.8 38.2 14.9 71.1 98.8 11.2 0.0 19.7 9.7 0.1 577.3 312.6 0.6 77.1 374.8 26.5 85.3 25.2 0.2 0.0 4.1 222.4 0.2 0.0 3.2 0.3 4.0 0.0 0.0 0.0 0.1 19.3 149.6 0.2 0.0 581.6 0.0 37.2 0.5 10.7 2.1 0.0 0.0 0.1 602.3 0.3 0.2 0.4 45.8 0.0 0.7 0.1 142.6 0.3 0.0 0.0 0.3 5.4 0.1 0.2 10.5 143.3 224.6 0.9 1.8 14.9 27.6 5.9 0.0 0.2 0.1 0.0 7.3 0.0 94.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 5.7 7.4 7.2 12.4 5.4 6.7 9.8 7.7 8.6 9.2 9.7 11.2 13.6 0.0 3.7 0.0 0.4 13.0 0.2 0.0 0.6 0.0 2.1 2.9 1.4 4.3 0.8 1.8 0.0 6.8 1.1 0.2 0.0 0.8 2.9 6.2 136.6 9.5 6.0 0.0 0.0 0.0 4.9 246.9 5.6 3.5 1.3 0.3 45.7 0.5 33.3 0.0 0.0 0.6 0.0 5.9 22.7 1.7 73.3 15.5 12.4 16.9 0.6 0.0 0.0 0.0 0.1 0.3 0.1 33.1 0.2 0.7 0.0 0.5 0.0 0.1 0.0 44.8 28.0 0.3 0.4 1.2 11.5 12.4 2.6 126.1 0.2 0.2 OLIG1 "BHLHB6, bHLHe21" ENSG00000184221 "Oligodendrocyte transcription factor 1" Q8TAK6 21 33070141-33072413 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 178.0" "Cell type enhanced" "Detected in some" "Distal tubular cells: 64.6;Oligodendrocyte precursor cells: 371.5;Oligodendrocytes: 134.7" "Cancer enriched" "Detected in some" 18 "glioma: 116.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "basophil: 12.1;eosinophil: 37.6" "Lineage enriched" "Detected in many" 15 "granulocytes: 37.6" "Group enriched" "Detected in some" 6 "NB-4: 39.2;RPMI-8226: 20.8;THP-1: 25.5;U-937: 29.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 70: Brain - Nervous system development" "Cluster 24: NB-4 - Immune response" "Cluster 68: Oligodendrocytes - Mixed function" "unprognostic (4.13e-2)" "unprognostic (6.46e-2)" "unprognostic (4.06e-1)" "unprognostic (3.58e-1)" "unprognostic (9.01e-3)" "unprognostic (2.40e-1)" "unprognostic (7.93e-2)" "unprognostic (1.50e-1)" "unprognostic (3.82e-3)" "unprognostic (5.19e-2)" "unprognostic (8.17e-2)" "unprognostic (2.51e-1)" "unprognostic (4.05e-2)" "unprognostic (5.96e-3)" "unprognostic (3.20e-2)" "unprognostic (1.17e-1)" 0.0 0.0 126.5 0.1 168.1 0.8 0.0 132.7 127.3 0.0 34.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 103.6 121.3 2.8 0.1 0.7 0.0 154.2 156.5 0.0 0.1 0.0 0.5 0.0 128.1 0.0 0.0 0.0 0.2 0.0 1.3 0.8 0.1 0.0 118.4 0.6 0.2 2.0 144.5 0.0 0.0 0.6 0.0 0.1 0.0 178.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.0 2.6 0.7 0.0 0.0 0.0 0.0 1.8 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 39.2 0.2 0.0 0.0 0.0 0.1 20.8 0.0 0.0 1.3 0.0 0.0 0.0 4.7 0.0 0.2 25.5 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.6 29.1 1.6 12.1 2.4 37.6 0.0 0.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.5 0.0 2.5 0.1 0.0 0.6 126.5 168.1 132.7 127.3 103.6 121.3 154.2 156.5 128.1 118.4 144.5 178.0 0.0 0.0 0.0 13.7 0.3 0.0 0.1 0.0 0.0 0.0 0.9 1.3 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 64.6 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.7 0.0 1.8 0.0 0.0 3.2 0.0 0.5 0.0 2.4 5.4 1.0 24.1 0.0 1.0 371.5 134.7 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.4 0.0 2.7 3.3 0.0 0.1 0.1 0.1 0.0 0.0 0.1 OPRPN "BPLP, PRL1, PROL1" ENSG00000171199 "Opiorphin prepropeptide" Q99935 4 70397931-70410195 "Predicted secreted proteins" "Protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "salivary gland: 146.5" "Cell type enhanced" "Detected in some" "Breast glandular cells: 12.5;Breast myoepithelial cells: 3.3;Glandular and luminal cells: 2.1" "Group enriched" "Detected in some" 5 "breast cancer: 7.4;liver cancer: 4.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA065711 Approved "Secreted in other tissues" NA NA 63000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 35: Glandular cells - Unknown function" "HPA065711: AB_2685541" "unprognostic (3.11e-3)" "unprognostic (2.22e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 30.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 146.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.5 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 ORAI1 "CRACM1, FLJ14466, TMEM142A" ENSG00000276045 "ORAI calcium release-activated calcium modulator 1" Q96D31 12 121626550-121642677 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Adaptive immunity, Calcium transport, Immunity, Ion transport, Transport" "Calcium channel, Calmodulin-binding, Ion channel" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 60.1" "Cell type enhanced" "Detected in many" "dendritic cells: 92.3;NK-cells: 88.6;Theca cells: 86.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NB-4: 81.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016583 Approved NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 59: Non-specific - Translation" "Cluster 24: NB-4 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "HPA016583: AB_1848720" "unprognostic (2.22e-2)" "unprognostic (3.78e-3)" "unprognostic (7.82e-3)" "unprognostic (8.83e-2)" "unprognostic (3.20e-1)" "unprognostic (1.99e-3)" "unprognostic (4.25e-3)" "unprognostic (1.92e-1)" "unprognostic (2.00e-2)" "prognostic favorable (4.30e-4)" "unprognostic (1.41e-1)" "unprognostic (2.59e-1)" "unprognostic (6.84e-2)" "unprognostic (1.95e-1)" "unprognostic (1.83e-1)" "unprognostic (2.04e-1)" "unprognostic (1.57e-2)" 10.8 5.4 4.4 9.6 4.6 8.8 10.9 5.2 6.8 7.3 22.1 10.6 20.8 7.6 0.0 8.7 7.7 3.3 9.3 3.8 4.9 11.2 12.3 15.5 12.0 5.5 4.9 6.7 8.1 8.7 2.6 4.5 5.5 6.4 0.3 0.0 15.6 2.6 60.1 46.6 13.8 2.2 5.4 23.1 12.5 11.5 5.1 6.1 10.4 14.0 2.8 11.1 7.8 5.1 18.3 42.0 3.4 16.9 4.0 4.9 18.4 20.5 2.9 8.8 4.7 33.1 16.2 13.3 31.4 3.1 11.8 30.2 3.4 13.7 0.0 41.9 7.8 23.9 6.8 16.6 10.1 18.5 43.7 2.0 5.1 14.4 0.9 4.9 12.9 30.0 16.8 6.9 2.3 41.4 46.1 81.7 19.6 10.3 35.7 16.8 7.9 20.5 5.0 13.4 16.4 3.3 10.7 11.7 17.5 0.2 29.3 11.6 23.5 21.0 8.4 28.6 15.9 9.4 8.7 5.6 15.7 25.9 19.1 9.4 6.3 8.2 18.6 5.4 13.9 6.3 15.4 18.8 7.5 9.0 14.3 12.5 6.9 7.5 5.2 1.9 13.7 7.6 4.4 4.6 5.2 6.8 3.8 4.9 5.5 4.9 5.5 5.4 5.1 5.1 32.0 28.9 16.4 1.0 41.0 22.6 10.1 3.4 6.8 2.1 48.4 22.9 4.2 18.6 10.3 1.8 4.2 3.7 92.3 8.4 1.9 13.3 3.4 14.1 11.1 40.6 2.4 23.8 0.3 19.5 15.2 9.5 8.6 17.4 7.0 24.0 43.2 17.9 38.6 0.0 0.5 9.3 2.0 28.2 65.0 11.8 13.4 42.8 21.4 4.7 27.2 5.8 88.6 3.0 1.5 29.5 6.3 9.4 30.5 14.8 17.2 12.1 6.3 6.9 0.0 6.3 10.8 1.7 6.0 6.9 37.4 7.8 70.3 86.0 20.1 10.7 OSR2 FLJ90037 ENSG00000164920 "Odd-skipped related transciption factor 2" Q8N2R0 8 98944403-98952104 "Predicted intracellular proteins, Transcription factors" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 166.1;endometrium 1: 155.1;fallopian tube: 155.3" "Group enriched" "Detected in many" 4 "Endometrial stromal cells: 243.1;Leydig cells: 784.1;Peritubular cells: 758.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 16 "ASC diff: 542.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA052425, HPA063486" Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "Plasma membrane" Nucleoplasm "HPA052425: AB_2681826, HPA063486: AB_2685022" "unprognostic (1.72e-1)" "unprognostic (1.92e-3)" "unprognostic (1.03e-1)" "unprognostic (5.94e-2)" "unprognostic (1.57e-1)" "prognostic favorable (2.44e-5)" "unprognostic (1.70e-2)" "unprognostic (1.15e-2)" "unprognostic (1.89e-2)" "unprognostic (3.73e-3)" "unprognostic (3.01e-2)" "unprognostic (6.19e-2)" "unprognostic (1.57e-7)" "unprognostic (1.37e-2)" "unprognostic (2.39e-1)" "unprognostic (2.56e-4)" "unprognostic (8.54e-3)" 45.0 9.9 0.0 2.4 0.0 0.6 26.0 0.2 0.2 166.1 0.0 9.2 0.6 155.1 53.7 15.1 155.3 12.9 4.2 0.0 0.0 1.3 0.3 3.6 2.4 0.0 0.0 93.2 4.2 3.0 2.7 8.2 0.0 40.2 3.8 0.0 6.8 72.2 5.6 27.9 24.9 47.1 0.0 0.2 5.1 35.6 0.0 0.8 5.6 5.1 1.1 27.2 83.8 0.0 32.3 4.5 0.0 4.4 542.4 17.2 4.3 17.6 33.1 13.7 13.6 3.4 3.9 0.0 2.9 26.7 0.8 12.4 2.7 4.7 6.7 1.5 13.0 0.6 3.3 1.6 8.9 0.9 0.6 17.0 9.8 2.3 1.6 0.8 0.0 4.8 4.0 0.4 0.6 14.6 2.9 5.7 0.0 2.6 2.8 13.8 1.6 1.1 1.1 2.7 1.4 0.1 1.9 7.5 0.4 0.3 4.3 7.5 0.2 2.1 0.1 13.9 1.0 0.7 0.5 0.3 0.9 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.9 14.1 6.6 3.4 1.2 0.0 7.9 5.3 0.7 0.0 3.3 0.0 0.0 17.2 0.9 0.7 0.0 0.0 5.8 7.8 243.1 3.7 0.0 0.0 0.0 0.0 138.4 71.7 0.5 5.9 0.0 0.2 0.0 0.0 9.3 0.0 0.0 18.4 10.2 1.9 21.9 24.1 784.1 2.7 16.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.8 758.3 4.6 3.6 103.9 0.1 1.7 0.0 32.9 8.8 21.3 5.1 4.5 0.3 9.1 24.2 2.3 95.6 22.3 2.2 OTULIN "FAM105B, FLJ34884" ENSG00000154124 "OTU deubiquitinase with linear linkage specificity" Q96BN8 5 14664664-14699850 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Angiogenesis, Immunity, Innate immunity, Ubl conjugation pathway, Wnt signaling pathway" "Hydrolase, Protease, Thiol protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 26.8" "Cell type enhanced" "Detected in many" "dendritic cells: 70.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051074 Uncertain Approved "Plasma membrane,Mitochondria" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 20: HeLa - Mitochondria" "Cluster 24: Non-specific - Transcription regulation" Mitochondria "Plasma membrane" "HPA051074: AB_2681334" "unprognostic (4.81e-3)" "unprognostic (1.11e-1)" "unprognostic (4.00e-2)" "unprognostic (1.19e-2)" "unprognostic (7.48e-2)" "unprognostic (1.91e-2)" "unprognostic (7.94e-3)" "unprognostic (1.43e-1)" "unprognostic (2.48e-2)" "unprognostic (9.55e-2)" "unprognostic (1.02e-1)" "unprognostic (7.13e-2)" "prognostic unfavorable (2.59e-7)" "unprognostic (2.92e-2)" "unprognostic (2.28e-2)" "unprognostic (1.60e-1)" "unprognostic (5.02e-2)" 5.0 3.9 4.8 9.6 6.3 26.8 4.6 5.9 4.9 5.5 6.2 4.7 7.6 3.6 2.6 8.0 3.5 4.7 6.7 4.9 5.0 4.4 12.3 6.4 12.5 6.6 5.6 4.8 6.8 3.8 3.6 6.5 6.4 6.3 4.6 4.6 5.7 3.3 5.2 11.8 5.8 4.8 5.6 7.1 4.3 7.1 5.8 11.2 4.1 5.5 13.5 5.7 6.9 7.1 10.0 11.5 11.2 12.8 10.0 10.3 12.3 9.8 6.9 13.8 10.2 15.4 7.2 18.0 18.9 6.4 19.9 11.1 14.1 12.9 9.2 31.1 11.6 12.9 36.3 8.3 8.8 12.4 21.2 6.0 15.2 11.3 9.4 7.6 11.8 14.9 13.0 27.8 10.0 6.1 12.4 10.6 6.9 10.5 12.0 18.8 10.0 7.1 8.9 10.1 5.1 8.3 35.1 7.8 7.6 13.5 8.5 14.1 11.1 17.8 20.0 13.4 13.2 12.4 20.6 20.3 10.1 23.2 9.3 0.2 0.6 1.1 0.3 0.7 1.0 0.3 0.8 1.1 1.0 1.6 0.5 1.3 0.7 0.3 1.1 0.8 1.7 0.3 4.8 6.3 5.9 4.9 4.9 5.0 6.6 5.6 6.4 5.6 5.8 7.1 20.3 3.2 11.5 23.5 24.6 0.0 23.2 0.0 26.2 11.9 12.8 11.7 15.0 10.0 4.3 5.5 14.6 15.1 70.6 21.1 7.9 5.5 9.4 20.6 28.1 13.3 9.5 13.7 18.5 5.8 10.3 10.1 16.8 24.0 10.2 14.0 6.4 36.9 13.9 8.4 19.5 15.7 0.0 18.9 0.0 4.2 10.5 25.0 0.0 38.4 17.1 10.4 26.8 16.6 31.7 8.0 13.3 6.4 38.5 25.9 14.1 15.1 5.1 31.4 0.0 11.5 10.2 29.7 28.8 23.7 0.0 14.2 35.8 7.6 15.6 23.1 OXGR1 "aKGR, GPR80, GPR99, P2RY15, P2Y15" ENSG00000165621 "Oxoglutarate receptor 1" Q96P68 13 96985719-96994730 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 13 "Extravillous trophoblasts: 49.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 6 "myeloid DC: 1.2;plasmacytoid DC: 2.1" "Lineage enriched" "Detected in single" 7 "dendritic cells: 2.1" "Cell line enhanced" "Detected in some" "RT4: 3.3;SK-BR-3: 1.4;U-2 OS: 1.6" "Not detected" "Not detected" HPA067673 Supported "Plasma membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane" "HPA067673: AB_2685883" "unprognostic (1.83e-1)" "unprognostic (1.01e-2)" "unprognostic (1.33e-1)" "unprognostic (6.97e-4)" "unprognostic (7.23e-2)" "unprognostic (1.52e-1)" "unprognostic (8.38e-2)" "unprognostic (2.16e-1)" "unprognostic (1.16e-1)" "unprognostic (2.22e-2)" "unprognostic (4.14e-2)" "unprognostic (3.88e-2)" "unprognostic (1.89e-1)" "unprognostic (2.75e-1)" "unprognostic (1.54e-1)" "unprognostic (9.68e-2)" 1.3 0.0 1.0 1.3 0.8 0.1 4.2 0.5 1.5 1.0 0.5 2.0 0.2 0.5 2.5 2.1 1.6 0.1 0.2 0.8 2.1 4.0 0.0 0.4 0.1 1.2 1.3 0.1 0.5 0.3 0.3 0.9 1.0 0.5 1.6 0.0 3.0 0.4 0.2 2.6 0.4 0.5 0.7 0.4 0.2 0.1 2.6 0.3 0.5 0.3 0.8 1.7 0.6 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 3.3 0.0 0.1 0.0 1.4 0.0 0.0 0.7 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.1 1.0 0.8 0.5 1.5 0.8 2.1 1.2 1.3 1.0 0.7 2.6 1.3 0.8 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.6 0.0 1.7 1.4 0.2 0.0 0.0 0.0 0.0 2.4 0.1 0.2 1.9 0.0 0.2 0.7 0.1 0.8 1.2 0.0 0.6 0.0 49.7 0.1 0.0 0.1 0.0 0.0 0.0 0.0 1.8 0.0 0.6 0.5 0.0 0.0 0.4 0.1 0.0 0.3 3.6 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.9 0.0 0.0 2.2 0.0 3.7 0.0 0.0 1.2 0.0 P2RX7 "MGC20089, P2X7" ENSG00000089041 "Purinergic receptor P2X 7" Q99572 12 121132819-121188032 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 47.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 52.8;Oligodendrocyte precursor cells: 87.9;Oligodendrocytes: 156.7" "Group enriched" "Detected in all" 5 "glioma: 7.2;melanoma: 19.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 2.9;gdT-cell: 1.3;intermediate monocyte: 4.5;myeloid DC: 2.6;non-classical monocyte: 3.3;T-reg: 1.4" "Group enriched" "Detected in many" 5 "dendritic cells: 2.6;monocytes: 4.5;T-cells: 1.4" "Cell line enhanced" "Detected in many" "Karpas-707: 40.0;RPMI-8226: 24.8;SK-MEL-30: 41.0;U-266/70: 21.7;U-266/84: 20.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034968, HPA042013, HPA044141" Approved NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA034968: AB_10673105, HPA042013: AB_2677797, HPA044141: AB_2678830" "unprognostic (1.05e-1)" "unprognostic (4.90e-2)" "unprognostic (8.87e-2)" "unprognostic (6.54e-3)" "unprognostic (4.49e-2)" "unprognostic (1.55e-2)" "unprognostic (8.82e-2)" "unprognostic (9.11e-2)" "unprognostic (1.05e-2)" "unprognostic (1.08e-1)" "unprognostic (2.42e-1)" "unprognostic (6.62e-2)" "prognostic unfavorable (2.92e-4)" "unprognostic (1.91e-1)" "unprognostic (3.59e-2)" "unprognostic (5.55e-2)" "unprognostic (1.65e-1)" 2.8 2.5 20.2 5.1 28.5 2.9 2.0 23.1 30.7 6.1 11.3 3.6 1.5 4.1 1.5 1.4 2.3 3.5 1.3 21.8 20.7 0.7 4.6 6.5 5.9 26.3 24.7 8.3 1.4 1.7 1.8 2.9 28.3 1.8 2.3 0.5 2.5 1.8 0.6 13.1 1.8 4.2 21.3 5.9 1.6 1.3 26.2 1.7 1.0 1.0 3.6 2.3 4.4 47.3 0.1 0.0 0.0 1.0 1.1 0.4 0.8 0.1 1.9 0.7 1.7 0.0 0.0 0.1 0.1 0.7 4.3 0.2 0.0 0.0 0.5 1.8 0.1 0.7 0.0 0.1 0.8 1.6 11.6 1.0 0.0 2.0 0.0 0.0 1.9 0.4 0.0 40.0 0.0 0.0 0.2 4.4 0.1 0.0 0.4 3.8 8.9 24.8 0.0 0.0 0.5 2.3 0.2 0.0 41.0 0.0 0.6 7.8 0.0 0.6 0.1 0.1 0.2 21.7 20.2 0.1 2.4 11.8 6.1 0.4 2.9 0.0 1.3 4.5 0.5 0.3 0.6 0.6 2.6 0.2 0.5 0.6 0.3 0.6 3.3 0.4 1.4 0.9 20.2 28.5 23.1 30.7 21.8 20.7 26.3 24.7 28.3 21.3 26.2 47.3 2.0 3.2 4.8 12.1 3.9 6.9 3.0 0.0 1.8 3.9 1.8 2.2 2.4 5.7 3.7 0.0 2.1 3.5 9.0 1.2 0.0 1.2 0.6 0.7 1.6 3.9 0.0 1.7 52.8 0.0 0.9 3.7 0.0 0.3 6.3 2.6 5.3 3.9 23.4 1.7 18.4 0.2 0.0 21.5 35.0 1.5 11.1 34.2 16.0 34.7 21.2 1.3 7.2 87.9 156.7 0.2 0.0 10.5 1.3 1.2 0.1 0.0 3.6 1.0 6.6 3.2 1.9 1.2 0.9 1.0 3.7 4.0 6.6 4.1 0.1 1.0 P2RY1 "P2Y1, SARCC" ENSG00000169860 "Purinergic receptor P2Y1" P47900 3 152835131-152841439 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Blood coagulation, Hemostasis" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 25.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 23.3;Cholangiocytes: 21.5;Distal enterocytes: 25.4;Kupffer cells: 21.1;Squamous epithelial cells: 45.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 6.0;non-classical monocyte: 2.6" "Group enriched" "Detected in many" 9 "granulocytes: 6.0;monocytes: 2.6" "Cell line enriched" "Detected in many" 5 "HEL: 45.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA015577 Enhanced NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 36: HEL - Hemostasis" "Cluster 51: Myeloid cells - Hemostasis" "HPA015577: AB_1854882" "unprognostic (3.30e-1)" "unprognostic (4.52e-2)" "unprognostic (2.68e-2)" "unprognostic (4.76e-2)" "unprognostic (9.70e-2)" "unprognostic (1.40e-3)" "unprognostic (3.32e-2)" "unprognostic (2.53e-1)" "unprognostic (5.14e-1)" "unprognostic (2.58e-1)" "unprognostic (4.68e-2)" "unprognostic (2.70e-1)" "prognostic unfavorable (2.04e-7)" "unprognostic (1.36e-1)" "unprognostic (8.98e-2)" "unprognostic (7.33e-2)" "unprognostic (3.20e-2)" 1.6 1.4 6.2 2.3 14.2 5.7 1.4 3.1 6.4 4.5 1.0 9.1 3.2 6.5 0.5 19.2 2.1 2.0 2.9 5.9 6.7 0.8 1.5 7.0 0.8 3.3 4.2 8.8 3.3 0.3 1.6 25.4 8.4 7.7 6.7 9.0 3.2 2.2 7.7 8.9 6.1 4.5 4.9 2.2 0.9 1.1 8.2 1.6 1.3 3.4 2.7 2.4 8.0 4.1 0.0 0.7 7.0 0.0 1.1 0.1 0.0 0.0 0.1 0.2 0.6 9.0 0.1 0.0 0.7 0.0 1.1 1.5 3.9 1.3 0.3 0.0 3.4 45.9 0.1 0.0 0.0 5.4 4.0 0.5 8.7 0.0 0.4 3.5 0.0 1.5 1.4 0.0 0.0 0.1 0.8 0.1 6.4 0.0 5.5 0.0 0.2 1.3 0.0 3.1 1.1 0.0 0.0 0.0 0.9 1.6 0.0 2.4 0.0 0.7 1.8 0.0 3.9 0.0 0.0 0.0 4.5 0.0 5.2 6.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 2.6 0.5 0.0 0.1 6.2 14.2 3.1 6.4 5.9 6.7 3.3 4.2 8.4 4.9 8.2 4.1 1.0 0.0 0.5 12.7 0.8 1.9 6.7 3.3 15.9 23.3 0.5 0.1 7.1 21.5 1.0 0.0 0.0 0.2 1.6 25.4 0.0 1.3 0.2 1.9 12.0 7.1 0.0 10.8 0.0 0.0 0.3 5.6 0.0 2.7 10.1 0.1 11.7 0.3 7.4 0.0 0.2 8.9 0.0 21.1 0.3 0.8 14.9 15.9 0.0 1.0 1.8 19.1 0.0 0.0 0.6 0.9 12.3 6.0 0.0 6.3 13.4 0.2 0.2 1.5 0.0 1.2 1.0 0.4 2.2 45.4 2.0 0.1 0.5 3.5 8.3 4.9 PACSIN3 SDPIII ENSG00000165912 "Protein kinase C and casein kinase substrate in neurons 3" Q9UKS6 11 47177522-47186443 "Plasma proteins, Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "heart muscle: 161.8;skeletal muscle: 480.9;tongue: 279.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 112.0;Extravillous trophoblasts: 60.6;Muller glia cells: 63.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "T-47d: 127.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039480, HPA043904" Approved Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 20: HeLa - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" Cytosol "Plasma membrane" "HPA039480: AB_2676531, HPA043904: AB_2678725" "unprognostic (1.75e-1)" "unprognostic (1.11e-1)" "unprognostic (1.73e-2)" "unprognostic (3.10e-2)" "unprognostic (1.21e-1)" "unprognostic (6.89e-2)" "unprognostic (4.66e-2)" "unprognostic (8.17e-2)" "unprognostic (2.85e-1)" "prognostic favorable (2.09e-4)" "unprognostic (3.86e-3)" "unprognostic (1.26e-1)" "unprognostic (2.75e-2)" "unprognostic (9.72e-2)" "unprognostic (1.92e-1)" "unprognostic (1.29e-1)" "unprognostic (4.76e-2)" 14.4 66.5 19.6 4.5 28.2 0.4 18.4 24.5 20.9 33.3 18.8 50.2 4.7 33.5 11.4 52.6 29.1 7.2 161.8 18.0 19.4 14.8 43.6 15.9 2.0 33.8 27.5 23.2 33.1 11.0 6.2 16.1 32.1 35.2 2.7 4.5 40.8 20.6 480.9 41.4 11.3 21.2 25.0 4.5 33.5 4.5 25.4 2.0 24.5 279.4 5.2 21.5 31.8 39.0 56.4 27.1 12.5 51.5 10.3 10.2 59.8 19.4 24.6 33.9 19.1 40.8 7.3 0.3 5.9 9.2 23.0 90.0 23.7 40.2 13.0 8.7 44.8 8.4 105.5 91.7 19.9 2.0 8.4 28.2 52.3 17.9 28.3 27.2 15.3 15.2 18.4 0.7 13.9 106.7 0.7 40.8 15.5 43.7 58.7 33.1 48.0 9.0 14.3 49.3 0.3 42.6 28.2 17.9 24.6 24.6 127.3 6.9 6.9 57.6 62.5 7.5 47.1 10.1 4.4 5.3 18.6 19.2 30.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 19.6 28.2 24.5 20.9 18.0 19.4 33.8 27.5 32.1 25.0 25.4 39.0 6.1 0.0 8.1 4.9 0.3 35.9 29.1 25.1 30.7 0.7 32.2 24.3 112.0 38.6 18.1 5.5 0.0 31.0 0.6 0.2 9.8 37.7 0.0 3.1 8.4 7.8 0.0 2.7 0.8 15.5 60.6 12.6 9.7 6.2 0.0 3.0 8.6 33.1 6.0 0.0 1.1 0.2 14.2 1.6 4.6 0.4 16.1 1.0 17.8 2.8 0.0 63.6 0.0 0.0 9.5 41.0 0.0 12.4 2.6 56.8 1.5 24.3 5.0 3.2 32.9 18.5 25.4 0.2 7.5 39.7 29.8 18.3 0.7 4.8 1.4 29.8 PADI4 "PAD, PADI5, PDI4, PDI5" ENSG00000159339 "Peptidyl arginine deiminase 4" Q9UM07 1 17308195-17364004 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Immunity, Innate immunity, Transcription, Transcription regulation" "Chromatin regulator, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "bone marrow: 105.1;lymphoid tissue: 29.9" "Cell type enhanced" "Detected in some" "dendritic cells: 8.3;granulocytes: 12.6;Macrophages: 14.6;monocytes: 22.3;NK-cells: 20.6" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 8 "basophil: 79.9;classical monocyte: 71.3;eosinophil: 97.5;neutrophil: 183.0" "Group enriched" "Detected in all" 9 "granulocytes: 183.0;monocytes: 71.3" "Cell line enhanced" "Detected in some" "HEL: 1.2;RPMI-8226: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA017007, HPA042825" Enhanced NA NA 29000 "Cluster 5: Granulocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA017007: AB_1854921, HPA042825: AB_2678189" "unprognostic (1.70e-1)" "unprognostic (2.25e-1)" "unprognostic (2.23e-1)" "unprognostic (2.98e-1)" "unprognostic (1.27e-1)" "unprognostic (1.13e-2)" "unprognostic (1.47e-1)" "unprognostic (4.91e-2)" "unprognostic (8.49e-2)" "unprognostic (5.22e-2)" "unprognostic (8.55e-2)" "unprognostic (1.81e-1)" "unprognostic (1.66e-3)" "unprognostic (1.50e-1)" "unprognostic (1.28e-1)" "unprognostic (1.56e-2)" "unprognostic (1.80e-1)" 1.8 0.1 0.2 0.7 0.4 105.1 0.3 0.2 0.8 0.1 0.2 0.1 0.1 0.1 0.0 0.4 1.0 0.4 1.1 0.3 0.2 0.5 1.7 7.9 0.3 0.3 0.1 0.1 0.3 0.0 0.2 0.5 0.3 0.2 0.0 0.0 0.2 0.0 0.2 0.2 0.2 0.4 0.0 29.9 0.4 0.1 0.1 1.6 0.3 0.3 0.2 0.7 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 79.9 71.3 97.5 0.4 5.7 0.2 1.1 0.5 0.7 13.9 1.8 2.6 4.5 183.0 4.5 1.8 6.2 0.4 35.8 0.2 0.4 0.2 0.8 0.3 0.2 0.3 0.1 0.3 0.0 0.1 0.4 0.0 0.0 3.7 0.0 2.9 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.4 0.0 0.0 0.0 0.0 0.0 8.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.3 0.6 0.0 0.6 0.6 0.0 0.0 12.6 0.1 0.0 0.4 0.2 0.0 0.4 0.0 0.0 3.3 0.4 0.2 0.0 14.6 0.0 0.0 22.3 0.0 20.6 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 4.0 0.0 0.0 0.1 2.3 0.1 0.0 0.0 PARD6G "PAR-6G, PAR6gamma" ENSG00000178184 "Par-6 family cell polarity regulator gamma" Q9BYG4 18 80157232-80247514 "Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 38.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 39.6;Oligodendrocyte precursor cells: 25.6;Squamous epithelial cells: 25.3;Suprabasal keratinocytes: 63.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HMC-1: 36.4;hTCEpi: 34.0;RT4: 27.9;U-2 OS: 28.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA047017 Uncertain Approved "Plasma membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA047017: AB_2679904" "unprognostic (1.11e-1)" "unprognostic (4.39e-2)" "unprognostic (9.88e-2)" "unprognostic (4.40e-2)" "unprognostic (2.97e-1)" "unprognostic (5.48e-3)" "prognostic unfavorable (3.19e-4)" "unprognostic (1.80e-1)" "unprognostic (9.96e-2)" "unprognostic (4.27e-2)" "unprognostic (1.17e-1)" "unprognostic (4.09e-2)" "unprognostic (6.86e-3)" "unprognostic (9.65e-2)" "unprognostic (1.01e-1)" "unprognostic (4.85e-1)" "unprognostic (2.72e-1)" 3.4 1.7 5.8 1.4 5.7 0.6 5.3 3.8 7.9 9.6 6.8 6.0 1.8 6.5 2.7 18.0 6.2 3.3 2.9 9.3 7.8 7.0 3.5 2.9 2.5 6.3 5.8 6.2 2.1 2.1 3.8 5.5 5.5 5.7 2.0 1.8 4.5 5.9 1.9 38.1 3.0 5.4 4.6 2.0 2.7 2.1 8.3 5.3 18.0 1.0 4.3 5.6 12.0 5.9 3.0 4.3 17.7 13.4 0.6 0.7 12.9 3.3 0.7 2.9 0.4 1.2 1.2 0.0 1.4 1.5 5.1 13.4 6.4 19.2 2.8 0.5 5.7 0.2 3.5 10.4 0.8 4.0 36.4 5.7 34.0 0.3 1.8 2.2 1.4 4.2 1.4 0.8 4.3 5.0 3.6 0.4 5.3 1.4 5.2 0.1 11.7 1.5 0.5 27.9 7.4 7.7 4.1 2.2 20.0 8.6 2.6 3.4 1.1 5.9 28.8 2.2 1.6 0.9 1.2 0.3 1.9 0.9 11.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.8 5.7 3.8 7.9 9.3 7.8 6.3 5.8 5.5 4.6 8.3 5.9 3.3 3.2 0.6 7.5 0.7 39.6 13.7 11.0 18.8 1.3 4.1 10.3 2.8 1.5 2.3 3.7 0.0 0.6 9.7 0.4 0.0 0.4 0.5 9.8 10.1 8.2 0.0 0.0 6.5 0.2 9.5 4.1 0.5 3.3 0.0 3.1 10.8 1.5 0.8 0.0 8.5 0.7 8.2 0.9 6.5 0.7 1.8 0.8 12.4 15.9 0.0 2.0 0.0 25.6 4.8 0.8 0.0 1.9 3.6 6.6 0.0 7.6 2.6 2.5 19.7 1.9 13.6 1.5 6.0 25.3 63.9 0.4 8.0 2.0 0.6 13.4 PARPBP "C12orf48, FLJ20641, PARI" ENSG00000185480 "PARP1 binding protein" Q9NWS1 12 102120183-102197520 "Predicted intracellular proteins" "DNA damage, DNA repair" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 9.3;lymphoid tissue: 7.5" "Cell type enhanced" "Detected in many" "Erythroid cells: 20.0;Spermatogonia: 17.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA039677 Approved Supported Nucleoplasm NA NA "Cluster 35: T-regs - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA039677: AB_10673426" "unprognostic (7.84e-3)" "unprognostic (1.34e-2)" "unprognostic (4.54e-3)" "unprognostic (3.03e-2)" "unprognostic (1.84e-1)" "unprognostic (3.03e-1)" "unprognostic (1.30e-5)" "unprognostic (2.52e-3)" "prognostic unfavorable (3.17e-4)" "unprognostic (2.38e-1)" "unprognostic (3.95e-3)" "unprognostic (2.83e-1)" "unprognostic (5.61e-8)" "unprognostic (3.50e-3)" "unprognostic (2.34e-1)" "unprognostic (9.16e-3)" "unprognostic (6.14e-2)" 0.8 0.6 0.2 3.1 0.2 9.3 1.8 0.3 0.4 1.2 0.1 3.0 2.3 1.2 0.5 3.6 0.6 1.1 0.4 0.3 0.4 0.8 0.6 0.6 4.2 0.3 0.4 0.7 0.2 0.3 0.2 2.3 0.3 1.0 3.8 0.2 0.9 0.9 0.4 1.9 2.7 1.7 0.3 1.2 1.8 3.9 0.3 7.5 0.5 0.3 5.1 1.9 1.1 0.3 13.5 27.2 23.6 13.7 3.8 3.4 16.7 19.9 11.0 32.0 27.9 14.8 10.4 25.4 11.4 7.8 16.2 14.5 38.5 11.7 34.2 25.7 22.6 31.9 15.7 13.9 1.1 33.5 9.1 3.3 2.8 22.3 14.4 8.3 21.6 18.9 31.0 15.3 21.1 10.7 30.5 31.1 31.7 17.8 26.6 20.4 38.9 16.7 10.3 21.1 15.9 14.7 13.8 16.6 11.8 24.0 27.1 12.1 8.5 16.5 15.7 20.2 25.3 11.3 24.8 22.8 11.4 33.7 22.4 2.6 0.4 1.0 0.5 0.6 0.1 1.1 0.9 0.8 0.7 0.7 0.5 0.6 0.0 0.5 0.4 0.7 1.8 0.7 0.2 0.2 0.3 0.4 0.3 0.4 0.3 0.4 0.3 0.3 0.3 0.3 1.1 0.0 0.0 2.9 4.3 3.7 1.5 3.6 0.6 1.9 2.4 2.4 0.7 1.5 2.5 1.8 0.0 11.3 2.3 1.5 5.9 1.6 2.5 3.0 11.6 2.5 1.8 20.0 4.1 1.3 13.9 4.8 6.1 3.0 5.7 15.0 2.2 0.1 6.5 3.3 5.3 3.1 10.2 5.7 4.3 2.6 1.2 3.1 0.0 3.7 1.7 0.2 2.1 3.5 4.1 1.2 0.8 0.4 14.2 0.7 1.3 1.8 1.4 0.9 0.0 1.1 2.8 16.0 17.7 9.8 1.6 3.6 4.1 9.3 7.8 1.6 PCK1 PEPCK-C ENSG00000124253 "Phosphoenolpyruvate carboxykinase 1" P35558 20 57561080-57568121 "Citric acid cycle related proteins, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Gluconeogenesis "Decarboxylase, Kinase, Lyase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 432.1;liver: 681.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 703.8;Distal tubular cells: 588.9;Hepatocytes: 1184.0;Proximal enterocytes: 2209.9;Proximal tubular cells: 3547.9" "Cancer enriched" "Detected in many" 5 "liver cancer: 99.3" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 9 "ASC diff: 20.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA006277, HPA006507, CAB017027" Approved NA NA 840000 "Cluster 81: Kidney & Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB017027: , HPA006277: AB_1079579, HPA006507: AB_1079578" "unprognostic (3.50e-2)" "unprognostic (5.60e-2)" "unprognostic (4.60e-2)" "unprognostic (8.62e-3)" "unprognostic (1.99e-1)" "unprognostic (1.28e-1)" "unprognostic (1.21e-2)" "unprognostic (4.43e-2)" "unprognostic (1.84e-1)" "unprognostic (2.37e-1)" "unprognostic (1.64e-1)" "prognostic favorable (1.47e-5)" "unprognostic (1.03e-1)" "unprognostic (6.40e-2)" "unprognostic (1.05e-3)" "unprognostic (2.21e-1)" 59.2 1.1 0.8 1.7 0.8 0.0 29.8 0.7 1.6 0.0 0.6 57.8 110.4 1.2 0.2 0.4 0.9 5.0 1.0 0.7 1.4 432.1 681.4 0.2 0.3 0.7 0.9 1.6 0.4 0.0 21.1 0.3 0.8 0.2 79.8 0.5 1.1 0.2 0.4 0.9 143.9 2.9 0.6 0.3 0.9 0.0 1.3 0.1 0.8 6.5 0.0 0.8 0.1 0.8 0.0 0.0 0.0 0.0 20.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 2.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.8 0.7 1.6 0.7 1.4 0.7 0.9 0.8 0.6 1.3 0.8 0.7 0.0 0.0 0.0 21.3 0.1 0.0 0.0 15.9 0.3 0.7 0.6 1.0 61.5 0.6 90.1 0.0 0.1 0.1 703.8 588.9 0.6 0.1 1.3 1.5 2.7 53.9 40.2 0.0 0.0 0.0 2.3 19.9 8.5 8.9 0.1 29.6 1184.0 0.0 3.3 0.0 293.6 0.0 22.6 0.0 0.0 0.0 12.8 0.0 1.9 0.0 9.9 0.0 0.0 0.0 0.1 285.5 0.0 0.0 0.0 2209.9 3547.9 0.0 0.4 0.0 0.3 6.0 0.0 0.1 10.3 0.3 0.3 10.2 1.5 348.5 0.1 PCNA ENSG00000132646 "Proliferating cell nuclear antigen" P12004 20 5114953-5126626 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, Host-virus interaction" DNA-binding "Cancer-related genes, Deafness, Disease variant, Dwarfism, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 383.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000148, HPA030521, HPA030522, HPA030523" Enhanced Enhanced Nucleoplasm No Yes 170000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB000148: AB_628110, HPA030521: AB_10600218, HPA030522: AB_10602096, HPA030523: AB_10602199" "unprognostic (5.21e-2)" "prognostic favorable (1.86e-5)" "unprognostic (2.96e-2)" "unprognostic (2.43e-1)" "unprognostic (3.17e-1)" "unprognostic (5.60e-3)" "prognostic unfavorable (2.61e-4)" "unprognostic (1.47e-2)" "unprognostic (2.22e-1)" "unprognostic (3.89e-2)" "unprognostic (1.01e-2)" "unprognostic (9.78e-2)" "prognostic unfavorable (3.03e-6)" "unprognostic (2.12e-2)" "unprognostic (2.29e-1)" "unprognostic (7.11e-3)" "unprognostic (7.46e-2)" 31.2 47.2 23.2 85.2 26.0 383.2 51.0 26.8 29.7 41.5 26.8 89.0 70.7 38.1 30.9 81.2 39.1 34.8 30.6 23.0 24.4 43.7 55.3 37.5 168.8 25.1 24.0 37.7 32.8 42.4 25.1 69.8 26.0 32.2 93.7 94.1 40.3 38.3 27.9 62.8 72.9 47.9 26.8 54.0 53.9 62.3 23.3 219.9 42.0 26.8 137.3 51.0 42.3 30.0 769.1 591.4 585.0 253.7 136.1 126.6 409.5 491.6 288.3 453.7 640.0 465.3 594.2 773.4 155.7 177.5 395.2 558.8 350.7 594.4 413.2 231.7 386.8 543.7 207.8 1098.3 57.8 753.7 233.0 92.6 138.2 387.2 91.7 95.3 263.3 503.6 493.9 631.2 449.7 278.3 1450.6 829.3 439.9 592.0 322.9 787.9 514.1 622.5 208.5 441.1 500.8 339.4 345.1 524.6 351.9 213.9 371.2 378.0 177.2 324.3 373.3 461.5 572.0 317.2 981.6 1313.9 145.9 707.4 426.2 5.0 23.2 18.5 36.5 23.3 45.7 33.5 45.7 37.1 32.6 29.2 41.6 37.3 7.7 43.6 24.7 29.9 48.1 36.7 23.2 26.0 26.8 29.7 23.0 24.4 25.1 24.0 26.0 26.8 23.3 30.0 32.4 44.8 26.0 2.9 40.6 67.7 44.4 121.4 44.3 42.1 27.5 45.2 14.5 21.5 60.5 58.8 27.1 171.5 44.3 42.9 60.7 51.6 176.0 30.2 21.4 34.8 19.9 189.0 4.3 39.6 175.6 38.7 21.9 27.7 22.7 53.1 29.6 27.1 96.7 32.0 5.9 53.9 75.3 24.2 33.4 109.1 36.1 32.7 37.4 3.7 47.6 74.0 23.7 4.0 13.5 28.3 20.3 40.3 56.6 23.3 33.3 46.1 44.1 97.1 52.6 29.2 46.1 149.1 101.1 65.5 49.7 66.4 48.6 29.6 84.5 40.4 PCOLCE2 PCPE2 ENSG00000163710 "Procollagen C-endopeptidase enhancer 2" Q9UKZ9 3 142815922-142889206 "Predicted secreted proteins" Heparin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 87.6;heart muscle: 123.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 138.0;Extravillous trophoblasts: 63.1;Fibroblasts: 225.8;Syncytiotrophoblasts: 241.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 65.5;RPMI-8226: 36.8;U-2197: 77.9;U-266/70: 68.6;U-266/84: 34.3" "Low region specificity" "Detected in many" HPA013203 Uncertain Approved Nucleoplasm,Cytosol "Secreted to extracellular matrix" NA NA 580000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" "HPA013203: AB_1855084" "unprognostic (1.31e-1)" "unprognostic (3.75e-2)" "unprognostic (5.71e-6)" "unprognostic (8.36e-6)" "unprognostic (3.03e-2)" "unprognostic (1.06e-3)" "unprognostic (2.78e-2)" "unprognostic (9.39e-2)" "unprognostic (1.60e-2)" "unprognostic (1.67e-1)" "unprognostic (1.36e-1)" "unprognostic (1.60e-1)" "prognostic unfavorable (1.96e-5)" "unprognostic (1.85e-4)" "unprognostic (1.43e-1)" "unprognostic (1.74e-4)" "prognostic unfavorable (1.08e-4)" 87.6 2.8 0.8 4.0 0.9 14.9 29.1 0.4 1.0 21.5 0.8 6.9 0.1 4.2 2.2 7.8 3.9 1.5 123.2 1.3 1.9 17.9 18.3 16.4 2.3 0.7 1.1 3.9 1.4 0.7 23.7 48.1 0.6 21.5 5.1 0.7 3.1 8.9 2.4 5.3 2.8 8.7 0.5 3.0 3.4 2.4 1.5 0.7 6.4 22.1 1.9 25.7 26.0 0.8 1.4 11.0 3.4 0.0 65.5 18.1 0.0 1.0 0.2 2.9 3.6 0.7 1.2 0.0 3.3 4.9 14.8 0.1 13.7 0.0 3.4 0.0 21.0 2.5 6.8 0.0 0.0 1.5 0.0 6.9 0.0 6.9 1.7 14.5 0.2 2.2 0.5 0.0 1.4 2.0 4.5 1.2 5.5 0.2 21.9 0.0 8.1 36.8 3.2 0.1 7.6 4.6 17.8 0.0 6.5 4.7 0.0 4.5 0.0 5.8 12.8 77.9 6.0 68.6 34.3 0.0 16.6 1.9 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.8 0.9 0.4 1.0 1.3 1.9 0.7 1.1 0.6 0.5 1.5 0.8 17.3 0.0 3.2 0.7 0.2 7.4 0.7 0.9 0.6 18.0 0.5 0.6 37.3 0.0 0.9 12.9 25.0 138.0 0.2 0.2 0.0 0.0 0.6 2.1 2.2 4.5 0.0 0.0 1.6 0.0 63.1 225.8 0.5 3.7 1.3 29.0 0.4 11.8 15.3 6.7 2.2 0.2 0.0 0.6 12.4 1.0 0.6 6.7 3.6 1.9 0.0 13.8 0.0 29.7 1.6 0.5 0.4 0.0 0.0 2.1 0.0 0.0 0.0 12.6 0.0 6.1 16.9 25.8 47.7 1.0 7.4 241.6 1.1 19.1 0.0 0.4 PCP4L1 IQM1 ENSG00000248485 "Purkinje cell protein 4 like 1" A6NKN8 1 161258745-161285450 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 71.7;pituitary gland: 84.3" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 35.8;Bipolar cells: 82.8;Inhibitory neurons: 34.0;Sertoli cells: 19.7;Squamous epithelial cells: 23.5;Urothelial cells: 39.9" "Cancer enhanced" "Detected in many" "urothelial cancer: 21.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "RT4: 13.8;T-47d: 8.9" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "olfactory bulb: 206.6" HPA052833 Enhanced Supported Approved Nucleoplasm,Mitochondria NA NA "Cluster 35: T-regs - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 15: RT4 - Unknown function" "Cluster 56: Bipolar cells - Visual perception" "Nucleoplasm, Mitochondria" "HPA052833: AB_2681968" "unprognostic (1.81e-2)" "unprognostic (9.39e-2)" "unprognostic (5.25e-2)" "unprognostic (2.07e-1)" "unprognostic (3.03e-2)" "unprognostic (1.87e-2)" "unprognostic (2.51e-1)" "prognostic favorable (8.10e-5)" "unprognostic (2.39e-1)" "unprognostic (1.92e-1)" "unprognostic (4.93e-2)" "unprognostic (7.37e-2)" "unprognostic (3.63e-5)" "unprognostic (4.81e-2)" "unprognostic (1.25e-1)" "unprognostic (2.09e-1)" "unprognostic (6.15e-2)" 2.7 0.4 14.1 0.8 71.7 0.1 1.8 19.6 33.2 4.0 0.9 5.6 1.7 1.8 2.6 18.8 2.1 2.0 0.8 6.8 14.7 0.9 4.0 4.6 0.2 39.7 23.3 2.2 0.5 0.4 84.3 0.3 39.8 11.0 2.5 39.2 1.9 16.4 0.4 5.6 2.8 6.6 28.1 0.3 2.0 1.8 15.2 2.0 0.7 1.5 2.6 35.6 17.1 13.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 1.7 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.3 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.1 0.0 0.1 0.0 13.8 1.9 0.0 0.0 0.2 0.0 0.2 8.9 0.3 0.2 0.0 0.0 0.0 0.0 0.8 0.9 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 14.1 71.7 19.6 33.2 6.8 14.7 39.7 23.3 39.8 28.1 15.2 13.9 0.0 3.2 6.4 2.0 0.0 0.0 35.8 8.3 12.5 82.8 3.2 1.0 0.2 0.0 7.6 0.0 6.2 0.4 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.3 0.0 0.0 3.1 1.3 1.9 0.2 4.6 0.3 1.3 0.0 0.0 0.9 0.1 0.0 34.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.8 0.0 3.5 0.0 5.0 1.4 0.2 0.0 1.9 0.0 2.5 0.0 0.6 0.9 5.9 19.7 0.0 10.0 1.3 1.5 23.5 0.3 1.8 0.0 0.0 0.0 39.9 PCSK6 "PACE4, SPC4" ENSG00000140479 "Proprotein convertase subtilisin/kexin type 6" P29122 15 101289784-101525202 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 153.6;liver: 160.0;lymphoid tissue: 81.4" "Cell type enhanced" "Detected in many" "Hepatocytes: 231.6;Horizontal cells: 196.9;Oligodendrocytes: 561.9;Theca cells: 106.5" "Cancer enhanced" "Detected in many" "liver cancer: 8.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 3.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 47.2;CACO-2: 35.7;HEK 293: 60.3;Hep G2: 53.8;OE19: 65.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004774 Uncertain "Secreted to extracellular matrix" NA NA 480000 "Cluster 15: NK-cells - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA004774: AB_1079583" "prognostic favorable (9.99e-4)" "unprognostic (1.09e-1)" "unprognostic (4.37e-2)" "unprognostic (2.46e-2)" "unprognostic (9.83e-2)" "unprognostic (8.14e-2)" "unprognostic (2.20e-3)" "unprognostic (8.56e-2)" "unprognostic (2.16e-1)" "unprognostic (2.39e-2)" "unprognostic (3.85e-3)" "unprognostic (2.01e-1)" "prognostic unfavorable (7.06e-7)" "unprognostic (2.02e-1)" "unprognostic (1.87e-1)" "unprognostic (1.15e-1)" "unprognostic (1.03e-2)" 5.3 2.2 17.5 3.0 67.3 1.1 11.2 57.8 37.0 2.2 4.2 16.5 6.8 2.0 3.3 9.0 2.8 3.1 20.0 19.3 34.1 3.2 160.0 3.6 2.5 113.0 64.5 6.1 2.6 0.6 5.1 32.0 95.6 3.1 14.8 7.6 2.8 0.6 11.4 10.1 10.1 3.6 42.9 81.4 9.8 13.0 54.0 20.9 2.2 16.3 1.8 3.7 2.6 153.6 19.7 14.6 2.6 0.9 0.2 0.4 47.2 0.7 2.5 0.0 0.1 35.7 8.3 0.4 2.4 0.6 1.1 11.4 12.5 1.5 0.0 2.8 60.3 33.5 8.4 53.8 1.6 4.5 0.4 0.3 7.5 0.2 0.2 0.2 0.1 4.3 24.5 0.2 0.0 8.8 0.1 4.7 9.3 65.9 6.5 0.2 0.4 4.4 4.4 25.4 7.3 8.6 26.2 1.5 9.1 6.6 2.2 21.9 0.2 0.3 1.2 0.3 0.2 0.5 0.6 0.7 0.2 0.6 7.3 0.8 0.2 0.9 0.2 0.4 0.3 0.5 0.4 0.2 0.1 1.0 0.6 0.5 0.4 3.3 1.3 0.4 0.1 1.2 17.5 67.3 57.8 37.0 19.3 34.1 113.0 64.5 95.6 42.9 54.0 153.6 1.7 3.2 0.6 2.9 1.3 0.4 0.3 0.9 0.6 1.7 15.4 6.6 2.0 8.6 1.4 1.8 20.9 6.7 0.6 22.6 0.0 0.6 1.6 4.7 21.6 4.9 0.0 3.2 19.4 0.8 24.3 15.5 1.5 6.9 0.0 4.2 12.5 231.6 1.4 196.9 30.8 3.7 0.0 5.2 1.1 2.4 10.5 1.7 0.0 5.6 1.0 1.7 3.1 25.6 561.9 7.3 8.2 0.0 0.0 1.7 2.3 0.1 1.2 1.6 0.0 2.0 1.0 4.7 2.4 0.9 0.1 3.3 1.0 106.5 8.5 0.2 PDE10A ENSG00000112541 "Phosphodiesterase 10A" Q9Y233 6 165327287-165988078 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Allosteric enzyme, Hydrolase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "brain: 67.2" "Cell type enhanced" "Detected in many" "Excitatory neurons: 204.7;Inhibitory neurons: 209.6;Microglial cells: 89.0;Oligodendrocyte precursor cells: 48.7;Oligodendrocytes: 51.8" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 6 "basal ganglia: 67.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 9.0;LHCN-M2: 12.5;RT4: 6.9;SH-SY5Y: 8.1;TIME: 11.3;U-2 OS: 7.0" "Region enriched" "Detected in all" 11 "basal ganglia: 350.1" "Region enriched" "Detected in all" 5 "basal ganglia: 194.1" "CAB045998, HPA047200" Supported NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB045998: AB_2162589, HPA047200: AB_2679981" "unprognostic (1.02e-1)" "unprognostic (3.63e-2)" "unprognostic (3.58e-2)" "unprognostic (2.91e-1)" "unprognostic (1.20e-1)" "unprognostic (1.25e-1)" "unprognostic (1.76e-1)" "unprognostic (1.23e-1)" "unprognostic (9.36e-2)" "unprognostic (6.03e-2)" "unprognostic (3.79e-2)" "unprognostic (9.24e-2)" "prognostic unfavorable (4.44e-7)" "unprognostic (3.59e-3)" "unprognostic (2.37e-2)" "unprognostic (3.44e-2)" "unprognostic (5.90e-3)" 2.6 1.3 3.1 0.8 67.2 0.0 2.3 5.5 10.7 1.3 0.0 1.0 0.2 2.0 2.4 0.4 2.4 1.5 3.6 2.1 2.5 3.8 0.3 1.0 0.5 1.6 2.3 2.3 0.5 0.5 2.7 2.5 0.9 1.7 0.2 1.9 0.4 1.7 0.4 0.3 0.7 2.1 0.5 1.4 1.1 3.4 9.6 0.3 6.0 0.5 0.4 3.2 0.9 0.1 0.0 2.4 5.5 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.3 0.8 0.0 0.0 0.0 3.8 0.1 2.2 0.0 0.0 0.1 3.9 0.0 9.0 0.0 0.4 0.0 0.0 0.0 0.0 0.6 0.0 0.0 5.5 0.0 0.0 0.0 12.5 0.3 0.9 0.0 1.1 0.0 4.7 1.5 5.8 0.0 5.9 6.9 1.8 8.1 0.0 0.0 0.4 0.7 0.0 0.0 11.3 0.1 7.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 3.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 67.2 5.5 10.7 2.1 2.5 1.6 2.3 0.9 0.5 9.6 0.1 13.8 0.0 0.0 10.4 0.1 0.4 3.3 0.4 0.0 7.2 0.3 0.3 7.3 0.0 1.2 5.5 2.1 7.8 0.0 0.0 3.9 2.0 14.3 0.2 1.7 13.4 0.0 0.0 204.7 0.0 6.1 6.6 1.1 0.4 1.3 0.1 7.9 0.0 0.8 16.8 209.6 0.0 0.0 0.0 0.0 14.9 0.0 0.2 1.8 89.0 0.0 12.6 0.0 48.7 51.8 0.1 0.0 0.4 0.0 17.9 0.0 7.2 0.9 1.1 0.0 12.4 5.0 8.8 2.1 0.1 0.3 2.9 0.1 1.6 0.1 6.9 PDE11A ENSG00000128655 "Phosphodiesterase 11A" Q9HCR9 2 177623244-178072777 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Allosteric enzyme, Hydrolase" "Cushing syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 6.3;parathyroid gland: 9.8" "Cell type enhanced" "Detected in many" "Early spermatids: 37.0;Hepatocytes: 11.1;Late spermatids: 46.4;Oligodendrocytes: 14.9" "Cancer enhanced" "Detected in some" "prostate cancer: 1.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 1.6;fHDF/TERT166: 2.4;HAP1: 1.4;Hep G2: 2.8" HPA034560 Approved "Intracellular and membrane" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 25: Spermatids - Spermatogenesis" "HPA034560: AB_10602140" "unprognostic (1.02e-1)" "unprognostic (4.73e-2)" "unprognostic (1.02e-1)" "unprognostic (9.61e-3)" "unprognostic (2.34e-2)" "unprognostic (1.43e-2)" "unprognostic (1.30e-1)" "unprognostic (2.28e-2)" "unprognostic (2.23e-1)" "unprognostic (3.91e-1)" "unprognostic (9.95e-2)" "unprognostic (2.80e-2)" "unprognostic (5.06e-2)" "unprognostic (1.04e-1)" "unprognostic (1.75e-1)" "unprognostic (4.11e-4)" "unprognostic (1.64e-3)" 2.3 0.3 0.8 0.1 2.0 0.2 1.7 1.9 1.2 0.6 0.6 0.5 0.8 1.2 0.4 0.0 0.3 0.4 0.3 0.6 2.1 0.5 6.3 0.0 0.0 2.5 2.1 0.4 1.1 9.8 0.9 0.0 2.7 5.2 0.4 1.4 1.4 0.8 4.4 0.1 0.5 1.1 3.7 0.1 0.4 2.8 1.9 0.1 1.3 1.3 0.0 0.0 0.1 3.2 0.0 0.4 0.2 0.1 0.0 0.0 0.0 1.1 0.2 0.0 0.3 0.2 1.6 0.0 0.6 2.4 0.3 0.1 1.4 0.0 0.0 0.0 0.9 1.1 0.1 2.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.2 0.2 0.4 0.1 0.6 0.0 0.3 0.2 0.0 0.2 0.0 0.5 0.0 0.3 0.7 0.0 0.1 0.1 0.2 0.1 0.0 0.0 0.1 0.3 0.0 0.1 0.2 0.0 0.0 0.4 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.8 2.0 1.9 1.2 0.6 2.1 2.5 2.1 2.7 3.7 1.9 3.2 0.1 0.0 0.0 2.3 0.2 0.6 1.4 0.1 0.0 1.7 4.2 0.8 0.0 1.5 0.1 0.0 0.0 0.1 0.3 0.8 0.0 0.8 37.0 0.3 0.2 0.6 6.7 2.7 1.6 6.7 0.0 0.6 0.0 0.2 0.0 0.0 1.4 11.1 0.1 0.0 8.2 0.9 6.1 1.2 2.1 46.4 1.5 0.3 0.0 0.0 0.0 4.7 0.0 6.0 14.9 2.3 0.0 0.7 0.0 5.4 0.6 1.3 0.1 1.0 0.0 2.0 0.6 6.8 6.9 0.0 1.3 0.3 0.3 0.3 1.3 1.0 PDE9A ENSG00000160191 "Phosphodiesterase 9A" O76083 21 42653621-42775509 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 74.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 90.8;Paneth cells: 105.3;Proximal enterocytes: 233.5" "Cancer enriched" "Detected in all" 5 "prostate cancer: 31.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 3.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AF22: 29.7;EFO-21: 30.0;MCF7: 23.2;NB-4: 34.7;NTERA-2: 41.2;SCLC-21H: 22.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011380, HPA011978" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 38: EFO-21 - Unknown function" "Cluster 45: Enterocytes - Digestion" Cytosol "Nucleoplasm, Plasma membrane" "HPA011380: AB_1855132, HPA011978: " "unprognostic (5.75e-2)" "unprognostic (9.92e-3)" "unprognostic (3.50e-1)" "unprognostic (1.08e-1)" "unprognostic (1.44e-1)" "unprognostic (1.40e-1)" "unprognostic (5.06e-2)" "unprognostic (3.99e-2)" "unprognostic (6.02e-2)" "unprognostic (1.60e-1)" "unprognostic (1.25e-2)" "unprognostic (5.01e-2)" "unprognostic (1.90e-2)" "unprognostic (4.01e-3)" "unprognostic (1.97e-1)" "unprognostic (6.55e-2)" "unprognostic (1.79e-1)" 9.4 11.1 12.3 3.9 15.1 0.5 10.8 14.0 12.9 7.2 8.6 74.7 2.9 5.1 19.4 3.7 10.6 6.8 4.3 10.6 12.6 29.8 4.2 4.9 4.8 12.4 14.4 3.5 4.1 6.5 9.9 10.3 12.7 38.5 16.4 10.7 12.7 15.8 2.4 7.0 47.3 8.8 11.0 18.3 13.4 1.9 15.0 7.8 6.5 4.8 3.1 18.9 6.2 12.0 0.0 2.8 29.7 3.7 0.0 0.8 0.5 0.0 0.0 0.0 0.0 3.2 18.2 0.0 30.0 0.0 2.2 0.0 2.7 9.8 0.0 0.0 10.4 0.0 0.0 6.4 2.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.5 0.0 0.0 23.2 1.5 34.7 41.2 14.6 0.0 0.0 0.0 1.2 20.4 7.6 22.5 13.5 5.2 0.0 0.5 7.0 0.2 19.1 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 12.4 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.9 0.2 0.1 0.2 3.1 0.6 0.4 0.9 0.0 0.4 1.0 0.3 12.3 15.1 14.0 12.9 10.6 12.6 12.4 14.4 12.7 11.0 15.0 12.0 18.6 3.2 5.0 43.4 1.6 1.0 10.9 4.2 6.2 26.4 13.4 12.6 1.6 5.7 2.4 18.4 0.0 0.0 1.0 90.8 29.4 7.3 0.6 18.1 8.5 11.9 13.1 3.2 5.6 2.4 0.1 5.9 1.5 26.8 1.3 6.1 5.7 0.9 7.5 35.3 10.8 25.8 8.2 1.3 0.8 2.2 11.8 1.6 28.4 31.9 1.1 11.0 0.0 29.1 16.6 5.3 105.3 6.0 0.2 28.1 233.5 8.9 1.3 2.8 13.1 0.5 6.4 0.4 2.3 0.5 0.6 0.4 3.8 16.9 24.4 15.0 PEX11A "MGC119947, MGC138534, PEX11-ALPHA" ENSG00000166821 "Peroxisomal biogenesis factor 11 alpha" O75192 15 89677764-89690783 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Peroxisome biogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hepatocytes: 38.7;Late spermatids: 39.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SK-BR-3: 54.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (3.67e-1)" "unprognostic (2.58e-1)" "unprognostic (1.18e-1)" "unprognostic (1.08e-1)" "unprognostic (3.73e-2)" "prognostic unfavorable (2.57e-4)" "unprognostic (1.40e-1)" "unprognostic (6.17e-2)" "unprognostic (6.80e-3)" "unprognostic (2.82e-2)" "unprognostic (2.38e-1)" "unprognostic (3.24e-1)" "unprognostic (2.74e-2)" "unprognostic (1.10e-2)" "unprognostic (5.44e-2)" "unprognostic (4.82e-2)" "unprognostic (1.32e-2)" 25.6 10.4 7.9 3.4 8.3 0.8 20.0 6.9 8.5 7.2 12.8 14.5 16.3 6.0 10.5 6.5 9.6 5.4 8.1 7.9 8.7 11.7 39.1 6.1 2.5 7.1 7.8 13.1 11.8 10.0 5.5 3.6 7.2 18.3 12.0 12.7 11.3 10.1 17.9 5.4 12.2 5.5 7.2 4.1 11.3 11.4 9.0 2.3 10.9 12.0 3.7 9.2 6.1 7.9 10.2 6.1 4.6 0.3 23.4 8.4 3.7 5.0 8.5 7.4 12.0 4.3 11.9 4.7 5.5 5.8 10.6 13.3 0.0 7.6 8.5 7.5 16.8 7.1 7.2 6.0 16.8 4.7 2.4 10.4 9.2 4.3 7.1 5.8 5.2 4.6 0.1 1.8 5.6 10.2 0.0 0.6 2.6 20.6 11.1 0.0 0.0 4.2 6.1 6.8 3.4 8.7 16.0 54.4 15.5 8.3 14.4 4.4 4.7 4.9 4.8 13.2 4.0 5.3 9.5 0.2 11.9 0.7 4.3 1.2 0.7 2.3 3.6 1.0 2.0 1.6 1.8 2.0 1.8 0.9 2.2 2.5 0.8 3.1 0.7 0.4 1.7 1.5 7.9 8.3 6.9 8.5 7.9 8.7 7.1 7.8 7.2 7.2 9.0 7.9 1.5 6.4 8.4 12.4 2.0 1.8 9.3 5.2 7.4 8.6 15.3 10.9 8.7 10.0 11.4 5.5 2.1 10.8 1.3 22.1 5.9 7.6 24.8 7.1 5.5 3.1 3.6 0.8 3.0 4.6 7.1 4.6 3.1 5.2 1.3 6.2 4.6 38.7 4.0 18.5 3.5 8.9 6.1 3.5 0.8 39.0 5.3 1.6 3.6 2.8 1.9 14.5 1.0 3.5 3.5 5.5 11.6 2.6 0.6 11.5 20.7 12.6 16.2 9.7 0.0 6.4 4.6 22.6 8.7 5.0 2.0 2.7 1.5 11.0 11.8 11.9 PEX16 ENSG00000121680 "Peroxisomal biogenesis factor 16" Q9Y5Y5 11 45909663-45918812 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Peroxisome biogenesis" "Disease variant, Peroxisome biogenesis disorder, Zellweger syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043286 Approved NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 22: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 1: Pancreatic cells - Digestion" "HPA043286: AB_10794179" "unprognostic (2.48e-1)" "unprognostic (1.95e-2)" "unprognostic (8.14e-2)" "unprognostic (3.15e-2)" "unprognostic (1.76e-1)" "unprognostic (1.53e-1)" "unprognostic (9.06e-3)" "unprognostic (9.06e-3)" "unprognostic (2.11e-1)" "unprognostic (1.10e-1)" "unprognostic (3.48e-3)" "unprognostic (1.51e-1)" "unprognostic (6.75e-3)" "unprognostic (5.72e-3)" "unprognostic (2.71e-1)" "unprognostic (1.00e-1)" "prognostic favorable (9.06e-4)" 23.4 27.1 22.3 10.9 23.8 20.3 22.2 23.4 24.4 18.2 16.6 20.6 21.3 18.7 6.3 21.3 18.9 10.1 17.0 23.0 22.7 26.7 50.2 16.2 16.6 26.2 23.6 18.3 40.0 10.1 32.0 6.7 23.2 21.7 5.1 4.4 21.6 9.7 18.1 27.2 25.3 6.0 21.9 24.5 27.6 25.8 23.6 11.8 21.8 7.5 8.6 20.1 18.0 26.0 15.0 19.9 6.7 16.8 11.0 13.2 19.4 11.6 15.2 15.5 12.0 22.6 10.7 25.6 15.0 10.9 14.7 27.2 6.9 23.0 3.7 22.4 23.6 16.7 28.8 20.1 34.8 24.9 33.8 21.3 20.1 9.4 15.1 9.1 17.0 21.9 13.4 29.6 10.7 42.0 21.3 32.5 15.1 28.7 20.0 18.4 16.8 29.4 10.0 26.5 17.0 22.7 13.3 27.1 24.5 4.2 40.4 21.1 13.6 14.8 19.0 36.9 21.5 47.1 33.1 16.2 16.2 14.7 16.2 35.3 44.1 36.8 47.9 51.0 44.9 57.0 48.9 49.6 47.8 50.5 44.4 46.7 32.2 44.9 38.6 44.7 61.1 46.1 22.3 23.8 23.4 24.4 23.0 22.7 26.2 23.6 23.2 21.9 23.6 26.0 25.1 3.2 5.4 3.9 35.7 16.6 24.4 47.6 19.4 15.7 25.9 22.4 3.8 22.8 25.1 14.7 10.4 39.9 31.9 45.8 50.9 37.3 25.9 19.7 13.8 21.5 28.1 25.9 4.8 88.7 22.2 15.7 17.9 20.3 21.0 16.2 21.8 68.6 34.2 15.2 5.1 26.5 30.5 37.7 19.7 32.6 19.3 20.0 21.4 3.7 46.6 28.8 26.8 5.0 10.6 55.9 49.2 14.3 27.1 26.1 90.5 68.1 26.4 18.0 32.9 16.8 24.4 27.2 15.4 21.6 21.0 64.0 33.0 19.9 29.6 28.2 PGAP4 "C9orf125, MGC12992, TMEM246" ENSG00000165152 "Post-GPI attachment to proteins GalNAc transferase 4" Q9BRR3 9 101473170-101533537 "Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 16 "Cardiomyocytes: 52.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTCEpi: 25.5;hTERT-RPE1: 28.8;OE19: 48.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011318, HPA054041" Uncertain Approved Mitochondria NA Yes "Cluster 45: Intestine - Brush border" "Cluster 21: OE19 - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA011318: AB_2668482, HPA054041: AB_2682353" "unprognostic (2.58e-2)" "unprognostic (4.76e-2)" "unprognostic (5.52e-1)" "unprognostic (2.81e-3)" "unprognostic (2.72e-2)" "unprognostic (9.15e-2)" "unprognostic (1.20e-3)" "unprognostic (2.26e-1)" "unprognostic (1.11e-1)" "unprognostic (4.24e-1)" "unprognostic (3.51e-2)" "unprognostic (2.09e-1)" "prognostic favorable (1.55e-8)" "unprognostic (1.62e-1)" "unprognostic (1.91e-1)" "unprognostic (2.50e-1)" "unprognostic (9.16e-2)" 3.9 10.3 21.5 2.2 21.3 0.5 2.4 18.9 26.2 16.6 4.5 13.4 8.4 7.1 3.7 14.4 13.7 6.8 30.4 24.9 26.1 4.7 2.4 5.4 0.4 17.9 13.4 19.5 11.1 16.6 12.3 0.6 26.1 6.9 11.2 9.9 6.1 9.4 4.8 12.0 7.6 6.7 9.6 1.6 16.0 2.8 19.2 0.9 4.2 6.1 2.4 6.4 11.9 20.3 0.0 14.6 11.3 0.0 0.3 0.2 0.0 9.8 14.1 7.0 13.8 0.7 7.8 0.0 3.2 17.9 0.8 23.1 0.0 16.1 4.2 0.0 5.8 8.1 10.3 0.0 0.5 0.0 0.0 6.2 25.5 0.0 3.8 28.8 0.1 0.0 0.0 0.0 14.3 0.0 0.0 0.0 14.0 48.1 0.0 0.0 5.7 0.0 10.5 2.7 18.9 17.8 5.5 0.0 0.0 2.7 0.0 13.8 0.0 10.7 6.6 0.0 0.0 1.0 0.0 0.0 15.2 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.5 21.3 18.9 26.2 24.9 26.1 17.9 13.4 26.1 9.6 19.2 20.3 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 52.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.1 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PGM2 FLJ10983 ENSG00000169299 "Phosphoglucomutase 2" Q96G03 4 37826660-37862937 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Muller glia cells: 334.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040676 Uncertain Approved "Intermediate filaments" NA NA 1700000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 5: Muller glia cells - Visual perception" "Intermediate filaments" "HPA040676: AB_2677076" "unprognostic (3.11e-2)" "unprognostic (1.01e-2)" "prognostic favorable (2.14e-5)" "unprognostic (2.29e-1)" "unprognostic (3.94e-1)" "unprognostic (5.44e-2)" "unprognostic (1.70e-2)" "unprognostic (2.09e-3)" "unprognostic (5.32e-2)" "unprognostic (7.02e-2)" "unprognostic (5.37e-2)" "unprognostic (2.22e-2)" "unprognostic (6.72e-3)" "unprognostic (3.21e-2)" "unprognostic (1.88e-1)" "unprognostic (9.97e-2)" "unprognostic (1.02e-1)" 8.2 11.2 3.2 9.5 3.2 10.1 8.8 4.6 4.5 10.9 4.5 9.8 7.6 10.1 4.9 36.6 7.9 11.3 5.6 4.9 3.1 8.0 14.8 6.9 10.0 3.4 3.0 6.9 4.4 8.4 3.0 11.7 3.6 7.8 9.0 18.2 7.7 5.2 1.2 17.5 7.8 13.7 3.5 8.3 6.1 5.3 3.1 10.2 9.7 1.9 22.7 18.9 16.4 3.7 27.4 9.5 14.6 16.6 10.2 12.4 19.8 32.6 18.9 27.8 26.4 18.0 19.2 38.0 15.5 17.8 34.9 13.8 36.0 32.0 65.1 23.0 21.0 40.1 15.2 12.3 23.2 44.2 26.5 17.0 36.0 22.0 18.6 16.2 41.6 31.2 53.6 6.2 24.3 15.6 49.8 49.6 17.3 19.2 15.5 35.8 23.1 14.8 15.7 52.3 31.8 10.8 17.5 23.3 12.0 19.5 21.5 45.4 37.0 19.7 24.9 27.3 67.1 14.0 38.4 40.3 10.9 56.2 32.9 19.8 27.5 67.2 9.8 22.4 11.5 9.4 8.0 11.1 31.9 5.5 7.7 9.8 33.6 28.1 18.2 7.1 14.9 17.0 3.2 3.2 4.6 4.5 4.9 3.1 3.4 3.0 3.6 3.5 3.1 3.7 16.9 0.0 8.2 5.2 13.8 14.7 14.3 32.9 17.6 7.8 12.6 6.9 4.5 14.3 23.1 3.7 0.0 31.9 11.9 10.6 5.9 16.0 0.9 9.0 12.7 22.9 7.2 8.0 8.3 11.8 37.8 10.3 5.6 14.7 12.7 56.4 42.5 9.7 37.9 6.7 5.6 9.2 4.1 24.4 15.2 2.0 8.4 24.5 5.4 4.7 46.1 334.1 13.4 8.0 0.9 14.5 6.7 9.8 10.5 17.7 6.9 10.4 9.8 16.0 13.1 5.8 23.8 0.6 2.1 42.5 32.1 79.8 14.7 19.8 12.9 20.4 PGRMC1 HPR6.6 ENSG00000101856 "Progesterone receptor membrane component 1" O00264 X 119236245-119244466 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 677.4" "Cell type enhanced" "Detected in all" "Hepatocytes: 520.4;Theca cells: 907.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002877, HPA064724" Enhanced Supported "Nucleoli,Endoplasmic reticulum" NA NA 1200000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 5: NTERA-2 - Transcription" "Cluster 52: Non-specific - Transcription" "Endoplasmic reticulum" Nucleoli "HPA002877: AB_1079602, HPA064724: " "unprognostic (6.97e-2)" "unprognostic (1.99e-1)" "unprognostic (1.72e-1)" "unprognostic (4.35e-1)" "unprognostic (6.51e-2)" "prognostic unfavorable (3.02e-4)" "unprognostic (1.58e-3)" "unprognostic (9.28e-2)" "unprognostic (4.66e-2)" "unprognostic (6.20e-2)" "unprognostic (3.08e-2)" "unprognostic (1.04e-1)" "unprognostic (1.14e-1)" "unprognostic (3.06e-3)" "unprognostic (2.08e-1)" "unprognostic (1.01e-1)" "unprognostic (1.11e-1)" 108.0 171.3 97.9 37.5 102.5 25.1 106.0 83.8 115.5 135.4 96.3 98.2 109.3 154.5 273.3 57.0 149.0 56.9 38.6 102.3 127.0 235.4 677.4 62.1 27.6 97.2 109.3 93.3 40.2 113.9 59.1 44.9 126.1 127.6 87.3 80.5 71.4 200.4 15.7 53.2 131.9 85.2 106.1 41.4 77.1 46.5 112.8 33.4 89.0 27.0 29.3 77.3 65.0 116.9 165.6 102.4 196.3 227.7 414.2 196.9 127.1 243.0 281.0 126.1 155.7 124.5 196.6 47.3 259.5 253.8 147.3 128.3 216.5 102.1 168.8 50.8 248.7 53.7 88.5 141.0 69.0 88.4 27.5 204.7 56.5 153.8 79.2 93.5 82.6 55.7 57.2 28.8 150.3 176.5 66.9 64.7 515.8 179.4 170.3 78.5 123.1 68.5 168.7 123.9 182.9 81.7 178.1 291.7 98.9 188.2 67.4 56.2 64.2 87.6 127.7 312.6 233.6 29.9 59.2 51.0 238.8 138.6 170.6 21.0 20.1 20.4 8.7 19.9 11.8 5.8 12.0 12.9 17.0 5.5 12.0 10.1 9.1 8.8 18.4 12.0 13.4 50.2 97.9 102.5 83.8 115.5 102.3 127.0 97.2 109.3 126.1 106.1 112.8 116.9 109.1 125.0 91.4 16.0 19.0 94.1 131.3 67.4 81.4 199.1 110.8 95.1 17.1 120.1 76.7 73.5 68.8 88.2 25.8 170.5 68.4 93.0 4.2 119.7 264.2 81.9 57.7 37.6 36.5 73.0 138.6 153.1 50.4 122.4 40.5 197.0 66.4 520.4 51.8 65.6 58.5 85.0 81.4 35.0 51.2 9.0 172.1 111.1 103.2 15.0 26.5 109.8 18.6 108.6 91.3 68.9 144.7 181.7 22.6 118.8 375.5 295.1 105.4 92.4 105.2 99.2 111.1 68.2 77.2 69.3 87.7 62.1 32.1 907.9 137.6 127.9 PHKA2 "PHK, PYK" ENSG00000044446 "Phosphorylase kinase regulatory subunit alpha 2" P46019 X 18892298-18984114 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" Calmodulin-binding "Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 42.7;Hepatocytes: 57.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002912 Approved Approved Nucleoplasm NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA002912: AB_10961321" "unprognostic (3.90e-2)" "unprognostic (2.06e-2)" "unprognostic (5.10e-2)" "unprognostic (1.43e-2)" "unprognostic (1.90e-2)" "unprognostic (1.12e-2)" "prognostic unfavorable (1.25e-5)" "unprognostic (2.07e-2)" "unprognostic (3.42e-1)" "unprognostic (1.82e-1)" "prognostic favorable (7.68e-4)" "unprognostic (7.51e-2)" "prognostic unfavorable (1.55e-5)" "unprognostic (2.05e-1)" "unprognostic (1.58e-2)" "unprognostic (7.16e-2)" "prognostic favorable (2.96e-5)" 12.7 9.6 4.6 6.8 6.3 15.0 7.6 6.6 5.5 9.0 6.9 6.8 12.5 10.5 6.5 6.3 9.9 8.1 12.6 5.6 5.4 6.7 34.3 6.4 7.7 6.9 5.6 16.8 15.2 8.1 12.8 10.5 6.7 9.7 6.5 10.6 9.5 7.1 7.8 8.8 10.1 6.2 5.5 9.3 8.6 9.7 6.0 12.6 10.1 14.3 7.4 6.2 8.1 7.3 11.3 10.6 6.1 10.2 8.2 7.5 16.6 4.9 4.1 7.1 7.7 11.3 7.3 13.3 3.6 6.4 11.2 10.3 11.0 12.8 7.6 6.5 11.2 15.9 17.6 13.8 5.8 15.2 19.7 12.6 8.3 8.7 12.5 11.8 7.4 13.8 5.3 8.0 5.0 12.0 16.0 25.2 7.5 5.2 11.2 12.4 12.5 14.9 4.6 5.0 5.2 8.0 14.8 15.3 6.8 20.3 18.9 8.8 13.2 9.6 5.3 10.3 7.6 7.6 6.7 10.1 5.4 8.1 5.2 4.3 3.2 7.2 2.0 3.8 2.1 1.6 1.7 1.5 2.1 1.7 1.9 1.9 5.4 3.0 2.5 1.1 2.3 1.9 4.6 6.3 6.6 5.5 5.6 5.4 6.9 5.6 6.7 5.5 6.0 7.3 6.1 9.6 12.9 27.7 5.7 6.5 5.4 6.0 8.6 11.1 8.0 7.4 20.1 12.8 5.1 9.2 10.4 16.8 3.4 9.6 0.0 7.5 7.2 6.4 11.8 7.3 4.2 14.5 15.2 5.1 17.5 5.3 4.1 7.2 1.3 42.7 20.3 57.4 8.0 5.0 19.9 7.4 4.1 18.9 3.8 5.3 7.5 10.5 5.4 13.1 8.3 17.0 7.2 16.6 16.9 6.3 12.6 7.9 7.4 6.9 12.4 4.8 4.1 13.3 0.0 7.4 5.9 7.9 7.9 8.6 4.7 10.5 7.4 12.1 10.7 3.6 PI4K2A "DKFZP761G1923, PI4KII, PIK42A" ENSG00000155252 "Phosphatidylinositol 4-kinase type 2 alpha" Q9BTU6 10 97640686-97676434 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 38.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB030649, HPA076857" Approved Approved "Plasma membrane" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "CAB030649: , HPA076857: AB_2686817" "unprognostic (1.34e-1)" "unprognostic (3.50e-2)" "prognostic unfavorable (4.21e-5)" "unprognostic (1.80e-2)" "unprognostic (2.12e-1)" "unprognostic (1.75e-2)" "unprognostic (2.84e-3)" "unprognostic (1.60e-2)" "unprognostic (1.39e-3)" "unprognostic (1.38e-2)" "unprognostic (1.02e-2)" "unprognostic (1.65e-1)" "unprognostic (9.92e-2)" "unprognostic (1.27e-1)" "unprognostic (1.80e-1)" "unprognostic (1.45e-1)" "unprognostic (2.90e-1)" 12.0 25.7 15.5 10.0 15.1 24.1 9.3 15.1 18.9 12.6 13.4 10.7 9.8 12.7 13.0 20.7 9.6 14.0 14.2 15.5 17.8 12.6 15.0 14.2 11.2 20.2 18.8 10.0 8.4 16.6 15.8 18.0 22.0 10.9 8.7 12.9 10.5 10.4 12.7 17.4 10.8 13.0 15.8 14.6 9.4 10.8 17.3 9.8 9.5 13.0 10.6 14.5 12.7 15.2 28.7 21.3 17.2 30.7 36.0 25.8 13.8 28.0 61.5 43.3 45.7 19.4 27.7 10.4 16.2 35.8 31.8 27.1 19.3 55.9 35.8 12.6 16.4 9.3 14.6 17.7 34.5 8.4 12.7 27.3 46.9 45.4 80.1 47.4 22.4 19.9 14.7 16.5 30.4 14.6 18.4 6.4 11.1 14.7 19.8 8.6 17.8 10.3 29.7 26.6 5.8 18.9 23.9 5.9 35.5 24.0 16.4 13.2 25.0 20.6 15.2 24.6 22.1 14.6 18.4 16.9 38.1 5.0 6.8 0.0 1.2 0.0 1.3 0.8 1.0 1.4 0.5 1.1 1.3 0.6 0.4 0.9 0.4 0.7 0.6 0.6 1.2 0.6 15.5 15.1 15.1 18.9 15.5 17.8 20.2 18.8 22.0 15.8 17.3 15.2 4.9 3.2 5.4 9.8 12.0 13.4 4.5 6.5 8.0 14.7 10.7 8.9 10.4 10.0 4.3 5.5 12.5 14.0 12.5 8.6 3.9 4.9 2.4 6.8 15.4 6.9 3.0 8.2 10.9 4.9 6.4 12.0 7.1 7.6 1.3 5.7 3.6 9.9 38.1 11.8 10.9 4.0 6.1 15.0 24.7 2.2 4.4 19.0 10.6 12.2 15.0 8.0 18.6 5.5 6.0 7.2 0.8 9.1 9.4 5.8 9.0 7.3 4.8 15.1 6.6 11.9 8.0 11.0 6.1 6.3 14.3 27.1 9.7 12.4 3.6 7.8 PIK3C2B "C2-PI3K, PI3K-C2beta" ENSG00000133056 "Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta" O00750 1 204422628-204494724 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 44.2" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 111.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive B-cell: 3.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 70.3;RT4: 75.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030515, HPA050360" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 70: Brain - Nervous system development" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Cytosol "HPA030515: AB_10670043, HPA050360: AB_2681104" "unprognostic (5.77e-2)" "unprognostic (1.36e-1)" "unprognostic (1.36e-1)" "unprognostic (2.18e-2)" "unprognostic (3.45e-1)" "unprognostic (2.19e-3)" "prognostic unfavorable (5.42e-4)" "unprognostic (3.35e-3)" "unprognostic (3.57e-3)" "unprognostic (2.72e-2)" "unprognostic (8.54e-2)" "unprognostic (1.10e-1)" "unprognostic (2.54e-1)" "unprognostic (5.36e-2)" "unprognostic (1.26e-1)" "unprognostic (1.75e-1)" "prognostic favorable (1.16e-4)" 12.0 3.6 10.4 15.2 23.6 5.0 9.7 8.5 23.3 7.4 0.0 15.8 14.4 8.4 4.8 12.9 6.5 8.0 10.6 11.2 18.8 10.2 4.9 17.2 23.4 19.2 20.4 3.0 5.2 3.2 3.3 12.8 17.1 6.2 12.9 2.9 7.2 5.4 20.9 21.2 14.9 9.9 7.3 13.6 18.9 1.9 28.0 22.3 8.1 10.8 22.1 10.9 10.7 44.2 7.5 14.8 12.9 11.9 7.4 0.6 70.3 0.9 2.9 2.8 2.1 8.8 19.2 12.7 2.7 1.7 2.5 18.3 7.7 5.2 1.1 7.7 2.1 0.3 30.1 3.3 0.4 4.5 9.3 0.9 5.4 0.7 0.4 1.1 19.1 12.6 4.7 8.3 0.2 16.7 15.4 12.8 11.8 29.3 9.3 16.6 3.3 2.4 3.5 75.6 14.1 7.8 26.0 35.9 8.4 4.7 16.1 2.4 0.7 0.4 4.5 1.3 0.2 8.9 2.6 16.4 0.5 6.7 1.9 0.0 0.1 0.0 0.5 0.0 0.5 1.5 0.6 0.4 0.1 3.2 0.3 0.3 0.2 0.8 0.0 0.0 1.2 0.2 10.4 23.6 8.5 23.3 11.2 18.8 19.2 20.4 17.1 7.3 28.0 44.2 26.7 0.0 12.2 16.0 15.3 3.8 2.1 7.9 1.2 16.6 5.3 4.4 6.9 5.7 6.9 3.7 0.0 4.4 3.3 29.2 0.0 1.8 0.6 2.0 2.5 26.1 9.6 0.0 14.3 3.4 4.4 4.5 28.5 2.4 32.4 8.5 31.1 5.5 4.2 15.2 22.8 23.8 2.0 1.6 5.1 0.7 1.2 2.9 3.6 27.2 2.3 2.7 4.1 23.6 111.5 4.7 14.5 7.5 4.9 2.4 14.6 2.1 9.1 1.0 0.0 7.7 3.3 0.1 1.5 8.1 8.0 2.2 5.0 9.4 15.5 13.8 PIK3CB PIK3C1 ENSG00000051382 "Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta" P42338 3 138652698-138834928 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Autophagy, Cell adhesion, Endocytosis" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 96.5;Inhibitory neurons: 92.4;Oligodendrocytes: 88.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HEL: 115.2;HMC-1: 185.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB031938, HPA042288, HPA064207" Approved Supported Nucleoplasm,Nucleoli,Vesicles,Midbody Yes No "Cluster 52: Eosinophils - Transcription" "Cluster 7: Kidney - Transmembrane transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "Nucleoli, Vesicles, Midbody" "CAB031938: AB_2165408, HPA042288: , HPA064207: AB_2685212" "unprognostic (4.89e-2)" "unprognostic (1.42e-2)" "unprognostic (5.97e-2)" "unprognostic (7.85e-2)" "unprognostic (4.89e-2)" "unprognostic (6.01e-2)" "prognostic unfavorable (6.42e-4)" "unprognostic (3.98e-2)" "unprognostic (1.35e-1)" "unprognostic (2.28e-1)" "prognostic unfavorable (3.99e-5)" "unprognostic (2.15e-1)" "unprognostic (6.18e-3)" "unprognostic (9.33e-2)" "unprognostic (7.82e-2)" "unprognostic (2.79e-1)" "unprognostic (4.59e-2)" 11.6 7.4 4.3 12.4 5.0 23.7 11.9 8.6 8.6 12.4 14.4 17.8 17.8 8.2 7.0 18.0 12.1 10.3 15.8 5.4 4.4 26.4 11.0 11.2 12.3 5.1 3.3 9.2 22.3 19.3 2.7 18.6 6.1 15.0 18.1 23.0 19.8 12.0 19.5 23.7 17.9 9.1 3.5 10.8 13.0 8.0 4.0 17.0 43.2 13.2 13.2 9.9 5.4 7.9 64.1 21.9 11.7 9.4 10.6 13.0 79.2 14.2 14.5 15.1 16.7 26.0 25.2 25.0 38.0 13.7 29.1 27.5 15.1 24.1 27.3 31.8 12.5 115.2 14.8 17.3 11.8 30.1 185.1 12.4 17.6 10.2 21.9 26.4 21.5 12.3 43.0 19.0 18.1 28.6 17.8 20.7 16.6 49.2 19.5 11.5 12.2 19.6 24.5 35.5 9.8 7.4 37.6 18.0 56.2 34.7 44.8 73.0 20.3 8.4 11.7 21.2 21.1 30.3 22.1 23.7 22.8 27.7 14.0 4.4 5.1 6.9 2.4 2.8 1.6 2.8 2.8 1.8 5.9 2.6 3.5 2.4 6.4 0.8 2.8 1.0 1.5 2.0 4.3 5.0 8.6 8.6 5.4 4.4 5.1 3.3 6.1 3.5 4.0 7.9 19.7 9.6 21.3 40.1 12.1 19.1 18.7 12.5 14.2 16.2 13.1 7.7 37.3 12.8 18.3 18.4 25.0 35.5 6.9 30.3 5.9 11.1 1.1 18.3 4.0 13.9 16.3 8.0 96.5 19.4 61.1 7.3 21.4 18.8 14.5 6.7 9.7 19.1 14.4 21.9 92.4 17.1 4.1 33.3 23.1 1.7 3.7 28.1 7.2 37.5 29.5 8.9 11.3 48.2 88.2 20.0 25.9 6.8 10.2 25.8 21.9 23.4 17.4 19.5 6.6 8.6 5.9 16.0 19.9 22.1 23.3 47.9 11.6 4.2 15.1 17.5 PIMREG "CATS, FAM64A, FLJ10156, FLJ10491, RCS1" ENSG00000129195 "PICALM interacting mitotic regulator" Q9BSJ6 17 6444441-6451469 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 13.9" "Group enriched" "Detected in some" 6 "Fibroblasts: 5.5;Granulosa cells: 21.5;Hofbauer cells: 7.2;Smooth muscle cells: 14.5" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebellum: 1.1" "Immune cell enhanced" "Detected in single" "NK-cell: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AF22: 161.8" "Region enhanced" "Detected in many" "white matter: 5.7" "Low region specificity" "Detected in single" "HPA043783, HPA049934" Uncertain Enhanced Nucleoplasm Yes Yes "Cluster 22: NK-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 12: NES - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA043783: AB_2678669, HPA049934: AB_2680959" "unprognostic (5.32e-3)" "unprognostic (1.14e-2)" "unprognostic (2.33e-1)" "unprognostic (4.37e-3)" "unprognostic (1.46e-1)" "unprognostic (1.24e-2)" "unprognostic (6.55e-3)" "unprognostic (1.23e-3)" "unprognostic (1.80e-1)" "unprognostic (5.88e-2)" "unprognostic (1.47e-3)" "unprognostic (1.50e-2)" "unprognostic (0.00e+0)" "unprognostic (8.65e-2)" "unprognostic (1.04e-1)" "unprognostic (1.01e-1)" "unprognostic (1.11e-1)" 0.5 2.5 0.3 1.3 0.0 2.5 0.8 1.1 0.4 0.9 0.0 3.3 3.0 0.8 0.0 3.3 0.3 0.7 0.3 0.1 0.1 0.3 0.3 0.7 1.5 0.2 0.0 0.8 0.2 0.1 0.1 0.6 0.0 0.3 4.1 0.4 0.7 0.1 0.0 2.7 3.1 2.0 0.0 6.0 1.2 0.3 0.1 13.9 0.4 0.0 2.1 1.3 1.3 0.2 42.1 54.1 161.8 73.1 1.5 4.5 12.6 47.9 29.8 78.6 52.5 32.8 17.9 0.0 18.8 39.8 39.9 29.9 82.6 21.6 41.9 64.6 33.9 0.1 33.8 41.2 0.2 1.7 48.9 2.4 1.5 32.2 12.4 8.0 24.8 36.8 10.1 23.0 49.9 30.5 9.2 0.5 70.9 34.0 37.8 74.9 64.8 29.6 12.9 6.4 36.5 51.3 41.7 42.5 39.1 20.4 19.9 4.0 11.9 59.9 48.4 36.0 80.7 8.2 31.5 0.2 23.6 20.4 94.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.1 0.0 0.1 0.2 1.0 0.1 0.0 0.3 0.3 0.3 0.0 1.1 0.4 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.2 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.3 1.8 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.0 0.0 0.2 0.0 0.4 1.2 0.6 0.0 0.0 0.0 0.0 0.6 5.5 0.0 0.7 1.3 21.5 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 14.5 0.0 0.0 0.0 0.0 0.1 0.8 1.1 0.0 0.0 PIP5K1B "MSS4, STM7" ENSG00000107242 "Phosphatidylinositol-4-phosphate 5-kinase type 1 beta" O14986 9 68705240-69009176 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 97.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 127.4;Early spermatids: 100.0;Inhibitory neurons: 270.1;Muller glia cells: 120.2" "Group enriched" "Detected in many" 4 "colorectal cancer: 10.1;pancreatic cancer: 3.4;stomach cancer: 9.4;testis cancer: 3.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "eosinophil: 34.5" "Lineage enriched" "Detected in many" 6 "granulocytes: 34.5" "Cell line enhanced" "Detected in some" "AF22: 43.8;HEL: 17.0;Hep G2: 13.4;OE19: 73.1;U-266/70: 17.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009687 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm Vesicles "HPA009687: AB_1855391" "unprognostic (2.02e-3)" "unprognostic (1.84e-2)" "unprognostic (3.77e-2)" "unprognostic (2.72e-1)" "unprognostic (1.56e-1)" "unprognostic (1.62e-1)" "unprognostic (5.85e-3)" "unprognostic (1.80e-2)" "unprognostic (1.38e-2)" "unprognostic (1.17e-1)" "unprognostic (2.98e-2)" "unprognostic (2.92e-2)" "prognostic favorable (1.03e-9)" "unprognostic (2.10e-2)" "unprognostic (1.71e-1)" "unprognostic (1.19e-1)" "unprognostic (3.34e-1)" 4.2 11.9 5.6 6.0 5.3 16.1 4.9 18.4 8.1 6.3 97.3 31.2 34.8 7.5 1.7 1.2 6.0 4.0 32.2 12.3 10.7 7.8 0.3 12.9 2.6 7.9 11.2 1.0 8.6 13.7 6.6 6.5 6.3 3.1 29.1 38.0 16.4 9.6 2.9 2.3 30.8 2.9 4.0 2.6 26.1 24.7 11.4 1.0 1.2 5.1 3.6 3.3 2.5 3.7 0.0 0.0 43.8 0.0 0.1 0.0 8.5 0.0 0.0 0.0 0.0 4.6 0.0 3.6 0.1 0.0 0.1 0.1 0.4 0.1 0.0 0.0 0.8 17.0 0.3 13.4 0.0 0.9 4.4 0.0 2.0 0.0 0.0 0.0 0.1 0.5 0.9 9.3 0.3 1.1 0.1 0.2 2.3 73.1 1.4 1.4 0.1 0.3 0.3 3.4 0.9 0.1 0.0 0.1 0.5 1.0 0.2 0.1 0.1 0.0 0.4 0.1 0.0 17.0 3.5 2.3 0.0 3.1 0.0 5.6 0.5 34.5 0.0 0.0 0.0 4.7 0.3 0.1 0.1 5.4 0.7 0.1 1.7 0.0 0.2 1.4 1.6 0.3 5.6 5.3 18.4 8.1 12.3 10.7 7.9 11.2 6.3 4.0 11.4 3.7 3.6 35.3 34.4 28.7 19.2 0.6 3.2 0.5 0.6 5.1 4.7 3.3 61.6 2.8 2.8 5.5 2.1 21.3 0.0 127.4 27.4 1.6 100.0 12.8 13.6 3.3 37.0 53.6 84.7 14.0 1.3 3.1 40.2 27.5 5.7 3.8 1.4 0.0 3.9 0.0 270.1 32.6 14.2 1.0 1.3 47.6 2.5 5.6 5.4 60.0 2.6 120.2 0.0 80.9 6.4 5.2 46.6 1.5 43.2 2.5 39.2 1.4 6.5 3.3 26.3 2.5 32.2 39.0 4.5 0.7 0.3 8.8 2.1 0.9 29.7 9.8 PLA2G3 GIII-SPLA2 ENSG00000100078 "Phospholipase A2 group III" Q9NZ20 22 31134807-31140508 "Enzymes, Metabolic proteins, Predicted secreted proteins, RAS pathway related proteins" "Cilium biogenesis/degradation, Lipid metabolism, Mast cell degranulation, Phospholipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "cervix: 5.9;esophagus: 13.8;skin 1: 15.4;vagina: 7.1" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 3.6;Breast glandular cells: 7.5;Suprabasal keratinocytes: 17.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 3.8" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "AF22: 15.1;AN3-CA: 15.3;NTERA-2: 7.8;SCLC-21H: 11.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA021016 Uncertain Uncertain "Endoplasmic reticulum,Golgi apparatus" "Secreted to blood" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 12: NES - Nervous system development" "Cluster 30: Mammary glandular cells - Lactation" "Golgi apparatus" "Endoplasmic reticulum" "HPA021016: AB_1855443" "unprognostic (1.80e-1)" "unprognostic (4.63e-3)" "unprognostic (1.07e-1)" "unprognostic (1.49e-2)" "unprognostic (9.72e-2)" "prognostic favorable (4.47e-4)" "unprognostic (1.74e-2)" "unprognostic (2.30e-1)" "unprognostic (4.25e-2)" "unprognostic (9.55e-3)" "unprognostic (4.41e-1)" "unprognostic (3.67e-1)" "unprognostic (3.29e-1)" "unprognostic (9.49e-3)" "unprognostic (3.72e-2)" 0.0 0.0 0.0 0.1 0.1 0.0 1.2 0.8 0.2 5.9 0.7 0.1 0.3 0.0 0.0 13.8 0.0 0.0 0.0 0.4 0.1 0.5 0.0 2.5 0.0 1.6 0.1 0.0 0.0 1.0 0.1 0.0 1.7 0.3 0.0 0.0 1.8 0.3 0.2 15.4 0.2 0.0 0.1 0.0 0.6 0.5 0.1 0.1 0.6 0.0 1.7 0.0 7.1 0.2 0.0 0.0 15.1 15.3 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.6 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 0.0 0.0 0.0 0.0 1.0 0.0 0.0 11.7 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.2 0.4 0.1 1.6 0.1 1.7 0.1 0.1 0.2 0.0 0.0 3.6 1.6 0.0 1.3 0.2 0.2 0.0 0.0 7.5 0.1 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.5 17.8 0.0 0.0 0.0 0.0 0.4 PLCH1 "DKFZp434C1372, KIAA1069, MGC117152, PLCeta1, PLCL3" ENSG00000114805 "Phospholipase C eta 1" Q4KWH8 3 155375580-155745071 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 16.6;retina: 12.4" "Group enriched" "Detected in many" 4 "Astrocytes: 93.7;Early spermatids: 206.2;Excitatory neurons: 126.0;Inhibitory neurons: 131.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 12.3;AF22: 39.0;HEL: 10.1;NTERA-2: 20.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036176, HPA057978" Uncertain Enhanced Vesicles NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 12: NES - Nervous system development" "Cluster 23: Spermatids - Flagellum & Golgi organization" Vesicles "HPA036176: AB_10671837, HPA057978: AB_2683569" "unprognostic (1.08e-2)" "unprognostic (3.68e-1)" "unprognostic (2.17e-2)" "unprognostic (1.55e-2)" "unprognostic (3.50e-4)" "unprognostic (6.41e-2)" "unprognostic (2.94e-5)" "unprognostic (5.04e-2)" "unprognostic (2.41e-1)" "unprognostic (2.24e-3)" "unprognostic (4.84e-2)" "unprognostic (1.76e-2)" "prognostic favorable (3.03e-5)" "unprognostic (3.28e-2)" "unprognostic (1.62e-1)" "unprognostic (1.47e-1)" "unprognostic (1.37e-2)" 0.0 0.0 5.5 0.3 4.8 0.2 2.6 4.5 6.0 1.2 9.3 2.5 2.5 0.7 8.2 0.1 8.1 1.5 1.8 3.8 1.4 1.2 0.1 4.0 0.0 1.3 4.6 0.1 1.4 0.4 1.5 0.4 1.5 0.3 2.4 12.4 1.3 1.9 0.2 0.1 2.5 0.1 1.6 0.0 3.8 11.3 1.3 16.6 5.7 0.0 0.0 0.4 0.1 2.0 0.0 12.3 39.0 1.5 0.0 0.0 0.0 0.0 0.0 0.3 0.2 2.4 9.8 0.0 0.8 0.0 0.1 0.0 7.0 0.0 0.0 0.0 3.6 10.1 0.0 1.4 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.2 0.3 0.0 0.0 4.4 2.4 9.4 20.8 1.3 1.6 0.9 0.0 0.0 2.4 0.2 3.6 0.9 0.0 9.4 0.0 5.7 4.2 0.0 0.0 0.0 0.2 0.0 1.7 0.4 0.0 0.0 0.0 1.3 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.5 4.8 4.5 6.0 3.8 1.4 1.3 4.6 1.5 1.6 1.3 2.0 0.0 3.2 13.6 93.7 0.3 0.0 0.4 0.5 0.6 10.5 4.0 5.0 0.8 4.3 2.3 1.8 4.2 0.0 0.1 2.7 0.0 2.2 206.2 34.6 1.3 0.6 3.0 0.0 126.0 2.3 0.3 0.3 15.3 13.6 0.0 0.1 0.0 0.0 0.2 25.2 131.5 4.0 0.0 0.3 0.4 21.4 1.2 0.4 0.0 12.2 0.1 16.1 0.0 5.5 5.7 1.5 4.6 0.4 0.0 0.4 2.8 2.1 23.4 3.0 0.0 0.0 0.2 2.4 1.2 0.7 0.1 0.0 0.3 0.1 4.4 0.4 PLCH2 "KIAA0450, PLC-eta2, PLCeta2, PLCL4, RP3-395M20.1" ENSG00000149527 "Phospholipase C eta 2" O75038 1 2425980-2505532 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 44.8;skin 1: 59.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 102.5;Cone photoreceptor cells: 75.0;Oligodendrocytes: 37.4;Rod photoreceptor cells: 169.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HBEC3-KT: 130.9;hTCEpi: 58.9;hTERT-HME1: 32.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072705 Enhanced NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 30: Epithelial cell lines - Translation" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA072705: AB_2732211" "unprognostic (2.06e-3)" "unprognostic (1.30e-2)" "unprognostic (1.09e-3)" "unprognostic (3.84e-3)" "unprognostic (1.99e-1)" "unprognostic (1.59e-2)" "unprognostic (7.39e-2)" "unprognostic (7.70e-2)" "unprognostic (7.58e-2)" "unprognostic (9.28e-2)" "unprognostic (2.26e-1)" "unprognostic (5.95e-2)" "unprognostic (6.61e-3)" "unprognostic (8.43e-2)" "unprognostic (1.07e-1)" "unprognostic (8.64e-2)" "unprognostic (5.80e-2)" 0.6 1.4 1.0 3.9 1.7 2.2 6.2 7.9 4.8 6.3 0.0 1.1 2.2 0.3 1.7 19.3 3.2 2.9 0.2 2.4 1.0 0.8 2.1 1.8 5.3 3.3 3.1 0.1 5.1 0.0 7.9 0.4 3.6 14.6 0.8 44.8 16.4 5.8 0.2 59.6 3.3 0.1 1.2 5.5 2.0 0.6 6.9 4.4 1.7 0.0 6.5 9.1 18.3 7.2 0.3 0.5 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.1 0.0 0.2 0.2 0.0 17.1 0.0 130.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 58.9 0.0 32.8 0.0 0.0 0.0 0.0 3.1 0.3 0.6 0.0 0.0 0.1 1.9 1.4 0.1 0.1 0.0 0.2 6.1 14.7 2.9 0.0 0.4 0.1 0.0 0.0 0.0 0.6 0.0 0.1 0.1 0.0 0.1 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.4 0.3 0.0 0.0 0.2 0.1 0.0 0.9 0.0 0.0 0.6 0.2 1.0 1.7 7.9 4.8 2.4 1.0 3.3 3.1 3.6 1.2 6.9 7.2 0.2 0.0 1.7 2.9 6.1 15.4 14.5 22.8 10.8 102.5 1.7 5.5 3.3 2.8 10.8 0.0 75.0 0.0 7.3 0.7 1.9 0.1 0.1 0.7 0.2 0.7 1.2 0.0 9.3 0.0 0.0 0.4 1.5 1.4 0.0 0.1 0.0 4.9 0.1 26.9 19.8 1.9 2.0 0.3 1.1 0.2 0.0 0.5 3.6 1.9 0.4 14.9 7.2 2.5 37.4 0.5 0.6 0.0 1.9 4.9 3.8 33.5 5.8 169.0 0.0 0.0 1.0 0.2 0.3 13.0 14.6 0.0 7.0 0.1 0.5 9.2 PLEKHA1 TAPP1 ENSG00000107679 "Pleckstrin homology domain containing A1" Q9HB21 10 122374696-122442602 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 336.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 6 "B-cells: 10.3;NK-cells: 21.3;T-cells: 27.1" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 203.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002043, HPA064795" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm Cytosol "HPA002043: AB_1079632, HPA064795: AB_2685354" "unprognostic (1.79e-2)" "unprognostic (3.18e-2)" "unprognostic (2.70e-1)" "unprognostic (5.44e-3)" "unprognostic (7.41e-2)" "unprognostic (1.69e-1)" "unprognostic (5.50e-2)" "unprognostic (4.07e-2)" "unprognostic (3.88e-1)" "unprognostic (2.69e-1)" "unprognostic (7.98e-2)" "unprognostic (7.63e-2)" "unprognostic (1.11e-1)" "unprognostic (1.46e-1)" "unprognostic (7.42e-2)" "unprognostic (4.31e-2)" "unprognostic (5.23e-2)" 18.0 10.4 21.2 13.9 25.5 4.4 19.6 10.7 42.0 18.6 5.0 21.4 25.9 25.9 20.5 39.4 12.7 24.0 29.2 25.9 14.8 39.1 38.7 36.6 14.9 12.4 14.9 19.2 27.3 27.6 21.8 37.3 13.3 17.9 20.1 19.8 25.2 18.8 31.8 66.5 25.1 23.6 13.2 13.7 21.2 40.7 13.7 15.6 27.3 57.4 18.0 24.9 21.7 36.9 25.9 23.5 23.3 16.1 33.1 37.5 28.0 28.2 49.1 16.8 18.0 20.0 31.8 16.1 13.3 25.6 17.0 55.4 22.3 86.1 15.4 11.4 21.8 0.0 22.6 23.6 21.8 2.9 7.3 20.5 69.7 13.9 58.3 27.5 56.8 33.2 24.3 0.1 15.6 9.9 14.8 2.5 18.1 39.3 15.5 4.0 33.1 3.2 203.2 28.3 31.6 15.5 36.4 26.8 28.9 32.7 14.9 0.3 54.6 14.1 11.5 15.4 14.3 0.1 0.0 5.4 21.6 0.1 8.8 0.3 2.7 2.3 27.1 2.4 17.5 5.1 16.3 21.9 3.2 10.3 25.4 21.9 0.8 21.3 2.9 1.6 11.9 11.6 21.2 25.5 10.7 42.0 25.9 14.8 12.4 14.9 13.3 13.2 13.7 36.9 48.6 144.2 42.0 19.9 28.0 72.8 54.7 51.6 97.9 46.5 25.6 19.2 55.9 55.8 46.0 57.0 75.0 58.4 47.6 39.1 41.1 63.1 202.0 50.2 30.6 70.8 22.3 6.9 133.8 85.3 53.9 34.3 28.1 83.7 5.1 20.8 32.5 45.1 37.2 26.9 92.9 19.6 22.4 23.7 23.6 336.5 44.1 20.4 24.9 35.6 28.5 20.2 147.2 35.2 161.9 71.4 26.9 36.1 7.4 91.4 64.4 118.1 29.1 49.5 26.3 32.2 28.9 119.4 86.1 71.6 84.8 39.7 39.7 14.7 27.5 83.5 PLEKHG5 "GEF720, KIAA0720, Syx, Tech" ENSG00000171680 "Pleckstrin homology and RhoGEF domain containing G5" O94827 1 6467122-6520074 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 57.4;skin 1: 102.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 17.4" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 57.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "NB-4: 32.1;TIME: 30.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049570 Uncertain Approved Nucleoplasm NA NA "Cluster 61: Skin - Cornification" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "HPA049570: AB_2680818" "unprognostic (5.59e-2)" "unprognostic (1.33e-1)" "unprognostic (2.47e-1)" "unprognostic (2.81e-1)" "unprognostic (1.50e-3)" "unprognostic (5.10e-2)" "unprognostic (1.02e-1)" "unprognostic (5.46e-2)" "unprognostic (4.40e-2)" "unprognostic (1.02e-2)" "unprognostic (4.85e-1)" "unprognostic (2.70e-2)" "unprognostic (1.28e-3)" "unprognostic (4.85e-1)" "unprognostic (1.20e-1)" "unprognostic (3.13e-1)" "unprognostic (4.85e-2)" 18.7 15.0 4.4 2.9 2.6 0.6 12.0 57.4 16.6 14.0 0.0 7.3 6.4 7.5 1.9 21.6 8.6 7.3 16.4 13.0 0.0 6.5 1.8 6.0 5.0 0.0 0.0 7.5 5.1 4.4 43.3 12.4 1.8 9.9 3.5 3.4 9.3 7.2 6.8 102.5 8.4 3.9 0.0 50.9 4.4 5.4 0.0 2.0 7.2 3.0 3.3 5.9 14.3 0.0 7.1 2.7 11.9 9.4 1.5 4.2 3.1 8.4 7.0 3.2 2.1 6.9 18.8 0.3 22.6 2.8 4.9 22.6 2.2 23.7 1.3 16.5 3.0 0.0 15.1 2.9 1.9 0.0 1.3 5.5 10.2 8.1 12.5 17.4 24.9 1.7 0.0 1.5 0.6 5.0 0.5 32.1 4.9 2.3 23.8 0.1 2.7 2.3 6.3 3.1 10.5 25.2 1.1 8.2 1.5 5.3 8.2 0.5 30.3 8.1 5.0 0.0 6.6 0.1 0.0 2.4 9.2 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 2.6 57.4 16.6 13.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 10.6 0.0 1.5 1.0 0.2 7.4 2.3 4.7 8.0 1.4 1.4 2.2 4.1 1.5 3.6 3.7 2.1 2.6 0.1 4.2 0.0 1.3 8.6 2.5 5.9 9.8 3.5 0.4 17.4 1.3 4.0 1.9 3.1 3.2 0.0 4.0 7.5 0.3 5.3 1.7 9.6 6.4 6.1 0.8 1.3 5.7 1.8 2.4 0.0 7.5 0.0 9.7 0.0 2.0 1.2 5.1 5.6 8.6 0.4 3.8 4.1 0.4 2.7 1.5 13.1 2.1 1.7 2.1 5.1 10.8 14.5 1.9 0.7 2.5 2.8 5.8 PLIN4 "KIAA1881, S3-12" ENSG00000167676 "Perilipin 4" Q96Q06 19 4502180-4518465 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 764.9;breast: 316.5;skeletal muscle: 249.9" "Cell type enhanced" "Detected in some" "Adipocytes: 12.3;Astrocytes: 12.1;Cardiomyocytes: 35.9;Hepatocytes: 30.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "ASC diff: 249.6" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA044682, HPA054657" Enhanced Enhanced "Lipid droplets,Plasma membrane,Cytosol" NA NA 55000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane, Cytosol" "Lipid droplets" "HPA044682: AB_2679044, HPA054657: AB_2682559" "unprognostic (2.97e-2)" "unprognostic (1.15e-2)" "prognostic unfavorable (8.31e-4)" "prognostic unfavorable (2.31e-4)" "unprognostic (6.65e-2)" "unprognostic (6.77e-2)" "unprognostic (1.03e-1)" "unprognostic (5.23e-2)" "unprognostic (9.89e-3)" "unprognostic (1.05e-1)" "unprognostic (2.95e-2)" "unprognostic (1.81e-1)" "unprognostic (1.90e-1)" "unprognostic (6.09e-3)" "unprognostic (3.10e-2)" "unprognostic (2.13e-1)" "unprognostic (4.94e-3)" 764.9 3.9 8.5 6.4 9.4 2.7 316.5 8.0 5.1 8.8 2.5 70.7 2.3 28.7 2.0 9.6 18.5 8.5 112.8 5.0 6.7 7.6 87.1 3.4 0.8 9.8 9.7 21.8 24.7 0.1 4.4 0.1 7.3 13.4 3.9 0.2 22.6 15.1 249.9 16.3 18.9 20.4 8.5 4.9 25.1 2.7 11.1 0.9 4.1 163.4 0.2 34.3 7.2 7.1 0.1 0.4 0.1 0.7 249.6 1.6 8.4 0.0 0.0 0.0 0.0 0.1 3.2 0.0 0.4 0.0 1.2 0.1 0.0 1.8 0.0 0.6 0.3 0.0 0.1 1.4 3.6 0.1 0.1 8.1 4.7 0.0 0.4 0.1 0.0 0.0 0.2 0.5 0.0 0.5 0.0 0.2 0.3 0.1 5.7 0.3 0.0 0.2 0.0 29.7 0.1 0.4 0.3 0.0 0.0 0.1 1.3 0.1 0.2 0.1 0.1 0.2 0.1 0.4 0.5 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.5 9.4 8.0 5.1 5.0 6.7 9.8 9.7 7.3 8.5 11.1 7.1 12.3 0.0 7.2 12.1 0.2 0.3 1.2 0.4 0.6 0.3 0.9 3.9 35.9 7.2 2.1 0.0 0.0 0.1 0.3 0.0 0.0 0.7 0.3 1.6 0.4 1.0 0.0 0.0 0.3 1.5 0.3 1.7 3.6 0.6 0.0 1.0 7.5 30.6 0.1 0.0 0.2 0.0 0.0 1.2 0.0 0.0 0.0 0.4 1.8 0.0 0.0 0.6 0.0 0.5 0.0 0.6 0.0 4.1 0.0 0.4 0.0 0.9 0.9 0.0 6.6 5.9 1.8 0.5 0.4 0.3 0.3 0.4 0.1 0.3 0.3 1.9 PMAIP1 "APR, NOXA" ENSG00000141682 "Phorbol-12-myristate-13-acetate-induced protein 1" Q13794 18 59899996-59904305 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 88.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 803.1;Endometrial ciliated cells: 463.6;Glandular and luminal cells: 529.8;Squamous epithelial cells: 474.5;Suprabasal keratinocytes: 691.2;Urothelial cells: 569.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 169.8" "Lineage enriched" "Detected in all" 5 "granulocytes: 169.8" "Cell line enhanced" "Detected in many" "GAMG: 207.5;U-138 MG: 202.1" HPA051063 Uncertain Uncertain Vesicles NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 41: Macrophages - Immune response" Vesicles "HPA051063: AB_2681330" "unprognostic (1.35e-3)" "unprognostic (5.02e-2)" "unprognostic (5.57e-2)" "unprognostic (4.88e-2)" "unprognostic (6.65e-3)" "unprognostic (3.76e-2)" "unprognostic (2.00e-3)" "unprognostic (1.26e-2)" "unprognostic (4.41e-2)" "unprognostic (6.12e-2)" "unprognostic (8.47e-3)" "unprognostic (5.56e-2)" "prognostic unfavorable (3.15e-6)" "unprognostic (2.53e-1)" "unprognostic (7.68e-2)" "unprognostic (8.74e-2)" "unprognostic (1.09e-1)" 2.0 0.7 2.8 8.0 2.7 88.1 3.9 2.6 5.1 6.5 3.0 2.5 3.7 5.4 0.2 13.7 2.9 8.0 0.9 2.6 2.8 2.3 2.1 3.8 14.7 2.8 2.7 0.7 1.2 14.8 16.7 13.4 3.0 3.6 3.4 2.0 3.6 1.3 1.5 24.1 3.9 1.9 2.7 4.6 2.5 3.1 3.7 12.1 2.1 1.5 14.2 17.3 7.9 2.4 26.6 17.4 5.2 1.6 8.8 69.0 19.8 125.4 84.1 71.5 70.7 1.7 32.5 104.6 17.0 23.5 207.5 38.4 21.0 11.8 70.4 33.7 154.5 19.4 26.0 4.6 87.6 67.1 28.2 28.7 30.8 93.8 48.5 26.1 24.0 46.7 26.7 17.5 24.1 2.6 53.8 20.1 151.7 2.7 32.7 54.1 28.8 39.1 41.9 24.2 39.7 32.7 6.1 3.2 71.5 56.1 5.3 54.6 90.6 202.1 54.0 10.3 141.4 2.8 0.3 92.1 16.8 37.6 48.5 169.8 16.7 103.6 10.9 26.2 9.6 33.8 5.0 6.8 12.1 25.0 4.1 5.9 53.5 6.3 32.1 10.2 25.2 15.1 2.8 2.7 2.6 5.1 2.6 2.8 2.8 2.7 3.0 2.7 3.7 2.4 29.2 32.1 25.7 0.7 175.3 803.1 316.2 236.4 415.4 0.2 111.8 82.0 4.7 12.8 129.6 3.7 2.1 120.3 125.3 141.1 0.0 54.7 0.8 463.6 48.8 48.5 133.4 5.5 0.0 67.0 14.7 32.9 168.2 529.8 31.8 11.8 7.9 0.5 89.5 0.0 0.0 146.8 181.0 37.2 363.3 1.1 0.9 140.6 74.7 7.5 142.4 0.3 34.0 0.0 0.2 100.1 123.6 1.2 63.1 265.7 94.7 0.5 101.5 0.7 0.0 10.8 32.0 0.3 19.8 474.5 691.2 315.2 117.0 19.8 122.2 569.2 PMFBP1 ENSG00000118557 "Polyamine modulated factor 1 binding protein 1" Q8TBY8 16 72112157-72176878 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 20.9" "Group enriched" "Detected in some" 6 "Early spermatids: 115.6;Late spermatids: 259.5" "Low cancer specificity" "Detected in single" "Region enhanced" "Detected in many" "pons: 13.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SCLC-21H: 21.0;SH-SY5Y: 10.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA056716, HPA075825" Approved Uncertain "Endoplasmic reticulum" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 68: Epididymis - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 31: Spermatids - Spermatogenesis" "Endoplasmic reticulum" "HPA056716: AB_2683215, HPA075825: " "unprognostic (1.46e-1)" "unprognostic (3.62e-1)" "unprognostic (5.95e-2)" "unprognostic (1.04e-1)" "unprognostic (2.44e-2)" "unprognostic (7.03e-2)" "unprognostic (1.06e-4)" "unprognostic (1.60e-1)" "unprognostic (3.81e-1)" "unprognostic (2.67e-1)" "unprognostic (1.03e-1)" "unprognostic (2.82e-1)" "unprognostic (2.68e-5)" "unprognostic (9.85e-2)" "unprognostic (2.66e-1)" "unprognostic (9.85e-2)" "unprognostic (8.67e-2)" 1.7 2.2 0.4 1.3 0.9 4.5 1.5 2.5 0.8 1.8 0.5 3.2 2.9 1.7 13.5 2.9 2.0 0.9 3.3 0.8 1.9 3.0 3.1 1.6 2.0 3.5 3.9 2.6 6.5 1.2 2.7 0.6 13.3 3.6 3.3 3.5 1.7 0.3 0.6 4.4 3.9 0.3 1.9 4.7 2.6 20.9 1.0 2.4 2.1 0.0 0.5 1.8 1.9 1.4 0.2 0.4 2.8 2.8 0.0 0.6 1.9 0.6 0.2 0.6 2.1 1.1 2.8 1.9 0.4 0.1 0.1 1.8 1.0 0.1 1.4 0.2 4.3 1.9 3.7 3.1 0.0 4.2 3.2 0.0 0.9 0.1 2.1 0.6 0.8 2.3 0.4 1.7 0.1 2.4 1.1 6.8 0.8 0.1 1.2 2.9 0.2 1.5 0.3 0.8 21.0 10.7 0.0 0.0 0.2 2.0 0.5 2.7 1.8 1.3 2.2 0.6 1.4 3.9 1.5 1.2 0.6 2.8 0.7 0.0 0.3 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.4 0.9 2.5 0.8 0.8 1.9 3.5 3.9 13.3 1.9 1.0 1.4 0.0 0.0 0.6 1.0 0.3 0.4 0.1 0.1 1.2 0.9 0.1 0.0 0.7 0.0 1.3 0.0 0.0 0.0 0.1 0.3 0.0 0.2 115.6 0.3 0.2 0.3 5.4 0.8 0.7 0.2 0.1 0.6 0.0 0.1 3.8 0.3 0.0 0.1 4.7 30.3 0.7 0.7 0.0 1.9 5.5 259.5 1.2 2.4 0.0 1.0 0.0 1.1 0.0 1.0 1.6 0.1 0.1 1.5 0.0 0.1 0.2 0.6 1.6 0.2 0.0 0.0 0.1 2.9 0.9 0.3 0.0 0.1 1.0 0.0 0.9 0.2 POC1A "DKFZP434C245, WDR51A" ENSG00000164087 "POC1 centriolar protein A" Q8NBT0 3 52075226-52154690 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Dwarfism, Hypotrichosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 12.8;testis: 17.6" "Cell type enhanced" "Detected in many" "Early spermatids: 47.9;Extravillous trophoblasts: 33.8;Late spermatids: 73.4;Spermatocytes: 40.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040600 Approved NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "HPA040600: AB_10672837" "unprognostic (2.68e-1)" "unprognostic (7.17e-2)" "prognostic favorable (1.78e-4)" "unprognostic (5.08e-2)" "unprognostic (3.61e-1)" "unprognostic (1.31e-1)" "unprognostic (1.02e-3)" "unprognostic (2.41e-2)" "unprognostic (7.23e-3)" "unprognostic (1.79e-2)" "prognostic unfavorable (1.76e-4)" "unprognostic (3.89e-2)" "prognostic unfavorable (9.43e-7)" "unprognostic (9.90e-3)" "unprognostic (1.96e-1)" "unprognostic (3.62e-2)" "unprognostic (2.32e-2)" 1.4 4.1 1.5 4.0 1.5 11.1 2.2 1.4 1.8 1.5 1.1 5.9 4.8 1.0 1.0 4.7 1.7 1.1 1.4 1.7 1.6 2.1 5.2 1.9 5.4 1.9 1.6 0.7 0.9 1.1 0.7 4.1 1.8 1.3 6.0 0.4 1.3 1.0 1.5 2.6 4.0 2.9 1.5 2.8 2.8 17.6 1.6 12.8 1.0 1.0 7.0 2.0 1.8 1.8 30.1 25.2 25.0 33.5 5.1 6.5 33.9 30.0 28.7 62.8 48.7 22.1 31.0 31.3 8.8 23.9 48.6 18.3 38.0 33.9 45.3 26.0 16.0 21.4 26.3 23.9 1.4 24.5 13.0 3.6 7.3 49.6 25.9 8.7 29.0 46.2 18.8 32.9 37.5 23.8 45.6 44.2 19.1 33.7 41.0 19.6 19.7 30.0 14.2 21.0 11.6 16.7 24.0 23.7 18.3 26.0 29.2 45.7 9.7 28.6 27.6 46.3 49.3 27.8 49.1 26.6 19.2 42.6 29.1 0.0 1.6 0.0 1.2 2.2 0.1 0.9 0.8 0.4 1.9 0.5 0.7 0.4 0.5 1.4 1.6 1.9 2.6 1.1 1.5 1.5 1.4 1.8 1.7 1.6 1.9 1.6 1.8 1.5 1.6 1.8 0.9 0.0 1.3 0.3 2.5 1.7 1.6 4.7 0.0 0.7 2.1 2.2 0.7 0.0 1.4 1.8 0.0 21.8 0.9 4.4 0.0 1.8 47.9 4.5 1.0 2.9 1.8 15.6 2.3 3.0 33.8 3.4 2.0 1.5 0.0 11.3 1.8 4.2 12.9 1.7 1.4 5.4 0.0 2.6 3.4 73.4 1.2 2.6 1.8 1.9 2.7 0.8 1.0 0.0 2.7 2.1 2.2 0.4 12.9 1.3 3.0 3.2 4.2 0.0 0.0 1.1 3.4 40.1 21.2 4.9 1.8 7.5 1.6 4.4 8.4 2.1 PODN "MGC24995, PCAN, PODOCAN, SLRR5A" ENSG00000174348 Podocan Q7Z5L7 1 53062052-53085501 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 13 "Fibroblasts: 123.5;Leydig cells: 268.7;Peritubular cells: 261.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "gdT-cell: 5.1;memory CD8 T-cell: 1.4;naive CD8 T-cell: 1.6" "Lineage enriched" "Detected in single" 52 "T-cells: 5.1" "Cell line enhanced" "Detected in some" "ASC diff: 23.0;BJ: 39.2;fHDF/TERT166: 23.9;HHSteC: 94.1;U-2197: 46.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA 910000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (8.69e-2)" "unprognostic (4.73e-2)" "unprognostic (3.18e-2)" "prognostic unfavorable (1.54e-4)" "unprognostic (1.46e-1)" "unprognostic (4.51e-2)" "unprognostic (2.31e-1)" "unprognostic (1.88e-1)" "unprognostic (3.65e-1)" "unprognostic (1.90e-3)" "unprognostic (1.71e-1)" "unprognostic (3.53e-2)" "prognostic unfavorable (2.02e-5)" "unprognostic (5.91e-3)" "unprognostic (1.62e-1)" "unprognostic (6.11e-2)" "unprognostic (5.02e-2)" 191.0 14.3 9.1 13.3 8.2 0.2 116.3 6.4 8.7 106.1 7.1 76.1 11.6 105.1 19.7 36.1 127.5 103.8 87.1 6.8 8.1 5.2 12.5 66.3 3.8 7.3 10.3 178.0 20.8 2.9 19.5 18.1 8.2 69.8 8.2 0.6 48.8 34.4 20.2 45.4 26.1 44.7 6.7 3.3 75.5 26.9 10.3 10.8 71.5 30.5 2.7 101.3 87.9 6.7 0.0 0.0 0.0 0.0 23.0 3.1 0.1 39.2 5.3 0.4 0.3 0.0 0.0 0.0 0.6 23.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 94.1 0.0 0.0 14.9 0.0 0.9 0.0 1.0 1.2 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.1 0.0 0.1 0.0 1.6 0.0 0.0 0.0 0.0 0.0 46.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.3 1.4 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.8 9.1 8.2 6.4 8.7 6.8 8.1 7.3 10.3 8.2 6.7 10.3 6.7 8.5 0.0 3.3 0.0 0.0 6.4 0.4 0.0 0.6 0.5 0.8 0.9 1.7 1.5 0.6 0.0 0.0 0.4 1.3 0.0 0.0 0.0 1.6 0.3 11.2 3.8 0.0 0.0 0.0 0.0 0.4 123.5 2.6 0.3 0.0 0.7 4.2 0.1 0.6 0.0 1.9 0.0 0.0 0.3 8.8 9.2 268.7 1.3 5.4 6.5 0.0 0.3 3.1 5.5 0.2 0.0 0.0 261.1 1.6 0.5 0.1 0.0 0.0 0.5 0.0 4.4 16.0 0.7 0.6 0.7 6.0 0.5 1.6 0.0 0.0 0.2 PON3 ENSG00000105852 "Paraoxonase 3" Q15166 7 95359872-95396375 "Candidate cardiovascular disease genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 20 "liver: 616.7" "Cell type enriched" "Detected in many" 11 "Hepatocytes: 509.6" "Group enriched" "Detected in many" 9 "liver cancer: 30.8;lung cancer: 7.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 28.9;CACO-2: 8.6;CAPAN-2: 6.5;Hep G2: 32.6;T-47d: 17.4" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA014848, CAB025250" Enhanced "Secreted to blood" NA NA 1760000000 380000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "CAB025250: , HPA014848: AB_1855540" "unprognostic (2.67e-1)" "unprognostic (1.03e-1)" "unprognostic (6.28e-3)" "unprognostic (5.52e-3)" "unprognostic (1.36e-1)" "unprognostic (4.87e-1)" "unprognostic (1.44e-3)" "unprognostic (6.32e-2)" "unprognostic (1.11e-1)" "unprognostic (6.44e-3)" "unprognostic (9.14e-2)" "unprognostic (7.18e-3)" "unprognostic (8.30e-9)" "unprognostic (1.66e-1)" "unprognostic (1.04e-2)" "unprognostic (8.29e-2)" "unprognostic (5.12e-2)" 1.4 3.8 2.1 0.5 2.0 0.0 31.2 1.7 1.9 5.3 1.4 2.0 7.9 0.9 3.6 0.5 1.3 4.4 1.0 1.8 2.1 2.7 616.7 14.2 0.1 2.3 2.2 12.4 14.3 0.2 24.9 0.8 2.9 0.9 2.8 0.1 26.3 3.9 0.3 7.4 3.1 0.2 2.1 0.3 2.3 9.0 2.1 1.6 7.1 0.3 5.9 1.4 0.9 1.9 3.1 28.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 6.5 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.6 0.0 0.0 0.0 0.1 1.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 5.3 0.0 0.1 17.4 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 2.0 1.7 1.9 1.8 2.1 2.3 2.2 2.9 2.1 2.1 1.9 2.5 6.4 45.9 24.5 0.6 0.9 0.9 9.3 1.8 0.0 5.4 4.3 0.5 31.5 23.9 3.7 0.0 1.7 0.3 3.2 1.9 0.3 14.5 0.0 0.4 1.9 0.0 8.0 0.1 2.0 2.2 5.2 0.5 0.0 0.0 0.4 10.0 509.6 0.2 0.0 0.2 1.8 12.2 8.1 0.3 4.8 8.1 0.2 14.2 4.7 0.0 3.2 0.0 17.6 0.1 1.2 1.2 3.0 0.0 2.1 6.0 6.7 6.5 0.1 0.0 0.8 2.1 21.4 16.9 0.3 1.3 1.4 0.8 6.6 2.3 0.4 POP7 "RPP2, RPP20" ENSG00000172336 "POP7 homolog, ribonuclease P/MRP subunit" O75817 7 100706121-100707486 "Enzymes, Predicted intracellular proteins" "rRNA processing, tRNA processing" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021007 Uncertain Supported Nucleoli,Vesicles NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoli, Vesicles" "HPA021007: AB_10963575" "unprognostic (3.19e-1)" "unprognostic (2.45e-2)" "unprognostic (2.72e-2)" "unprognostic (1.80e-3)" "unprognostic (6.47e-2)" "unprognostic (1.04e-1)" "prognostic unfavorable (4.99e-5)" "unprognostic (2.98e-2)" "unprognostic (2.28e-1)" "unprognostic (3.12e-2)" "unprognostic (9.50e-2)" "unprognostic (3.88e-1)" "prognostic unfavorable (6.02e-4)" "unprognostic (1.05e-2)" "unprognostic (1.44e-1)" "unprognostic (6.21e-2)" "unprognostic (6.73e-2)" 25.6 31.7 30.1 18.1 31.6 33.9 26.6 33.4 38.6 24.2 23.8 27.9 19.3 27.7 11.0 34.0 21.3 9.8 37.6 32.3 30.8 25.8 67.1 18.2 17.3 30.1 27.8 18.1 31.3 16.6 22.8 16.6 30.8 22.6 9.2 9.6 29.0 13.5 69.0 50.2 22.3 12.1 29.4 22.7 26.4 12.5 29.1 15.6 16.8 31.9 12.0 25.4 24.9 33.9 115.7 115.3 47.2 78.4 25.1 23.9 92.0 65.6 32.4 73.7 73.1 159.8 71.0 97.5 105.1 30.0 81.4 70.4 70.1 79.5 36.8 82.7 212.4 44.9 75.0 166.5 42.1 69.2 49.8 27.6 30.2 76.2 74.8 20.9 41.6 68.9 157.4 77.8 39.8 330.4 158.0 232.9 135.2 77.8 164.4 123.6 50.0 159.4 45.3 65.2 90.4 92.3 54.5 156.2 78.7 42.0 50.0 66.2 41.3 92.0 117.7 191.0 127.6 34.0 99.4 175.8 61.0 115.1 104.6 106.3 63.2 72.4 54.7 64.7 50.7 60.3 54.6 54.3 55.3 47.7 49.5 52.0 39.0 78.9 70.3 51.2 69.8 62.5 30.1 31.6 33.4 38.6 32.3 30.8 30.1 27.8 30.8 29.4 29.1 33.9 30.5 19.2 17.0 2.9 29.7 105.0 32.0 57.2 56.3 26.1 61.6 64.1 27.9 37.1 31.5 35.0 6.2 148.2 25.8 51.8 93.9 75.4 2.1 31.2 32.3 37.2 40.2 50.1 5.2 87.4 181.3 37.3 25.0 35.1 17.7 32.4 33.5 99.0 66.1 32.0 6.0 61.7 67.1 27.3 40.7 7.9 42.0 22.4 56.9 2.8 38.7 41.8 41.2 4.0 5.8 92.2 47.6 37.2 55.1 75.6 69.8 86.1 27.8 21.3 46.0 29.8 52.2 9.2 45.5 74.7 119.2 139.3 27.2 39.9 55.8 43.5 POPDC2 POP2 ENSG00000121577 "Popeye domain containing 2" Q9HBU9 3 119636457-119665324 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "heart muscle: 405.4" "Cell type enriched" "Detected in many" 4 "Cardiomyocytes: 272.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 10 "SH-SY5Y: 24.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA024255 Enhanced NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA024255: AB_1855545" "unprognostic (1.13e-1)" "unprognostic (1.17e-3)" "unprognostic (8.91e-3)" "unprognostic (9.48e-2)" "unprognostic (5.56e-2)" "unprognostic (7.64e-2)" "unprognostic (2.73e-2)" "unprognostic (2.43e-1)" "unprognostic (3.18e-2)" "unprognostic (1.72e-2)" "unprognostic (5.86e-3)" "unprognostic (1.80e-1)" "unprognostic (1.24e-2)" "unprognostic (6.26e-3)" "unprognostic (1.66e-2)" "unprognostic (2.12e-1)" "unprognostic (2.06e-2)" 3.6 2.1 0.6 3.8 0.5 0.3 3.3 0.8 0.9 7.9 1.3 95.3 2.8 12.5 2.6 2.0 9.6 10.9 405.4 0.5 0.5 2.4 1.0 2.5 6.7 0.6 0.6 2.0 1.3 8.4 1.3 1.4 0.6 16.3 6.2 0.9 3.3 49.2 77.7 2.8 12.2 24.0 0.5 2.8 10.7 1.0 0.6 1.5 2.4 96.9 2.5 35.3 6.0 0.5 0.1 0.2 0.5 0.0 0.2 0.2 0.0 0.4 0.1 0.1 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.3 0.0 0.4 1.0 0.0 0.3 0.1 0.1 0.0 0.1 0.4 0.2 0.2 0.0 0.3 0.0 0.0 0.2 0.0 1.2 0.0 0.0 0.0 0.2 0.3 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.2 24.8 0.0 0.0 0.6 2.5 0.0 0.3 0.0 0.2 0.1 0.2 0.1 1.0 0.0 0.2 0.2 0.3 0.5 0.5 0.0 0.7 0.3 0.0 0.4 0.1 0.5 0.4 0.0 0.4 0.8 0.2 0.0 0.2 1.3 0.2 0.7 0.1 0.6 0.5 0.8 0.9 0.5 0.5 0.6 0.6 0.6 0.5 0.6 0.5 4.7 0.0 0.5 1.0 0.6 0.4 0.3 0.5 0.0 3.1 0.9 3.0 272.7 0.0 0.9 0.0 0.0 0.5 2.3 0.4 0.0 0.5 0.3 0.6 0.5 6.4 3.0 0.0 0.8 0.2 0.1 8.0 0.5 0.3 1.3 1.6 1.4 0.2 1.6 1.7 1.2 0.8 0.0 1.0 2.3 0.8 1.2 1.6 0.0 2.8 1.8 1.2 0.0 1.0 1.9 0.5 0.2 1.9 0.0 0.8 0.7 0.3 1.9 2.4 59.2 5.9 11.1 1.0 0.3 0.1 0.6 1.2 1.6 0.6 0.3 0.2 POU3F1 "OCT6, OTF6, SCIP" ENSG00000185668 "POU class 3 homeobox 1" Q03052 1 38043829-38046793 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "brain: 10.3;skin 1: 32.6" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 27.3;Breast myoepithelial cells: 39.1;Cone photoreceptor cells: 22.9;Suprabasal keratinocytes: 55.8" "Group enriched" "Detected in many" 4 "cervical cancer: 1.8;head and neck cancer: 4.4;melanoma: 4.8;testis cancer: 1.3;urothelial cancer: 2.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 24.1;HDLM-2: 23.9;NTERA-2: 7.5;SCLC-21H: 5.7;SK-MEL-30: 28.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA055980, HPA073824" Enhanced Nucleoplasm NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA055980: AB_2682995, HPA073824: AB_2686635" "unprognostic (9.99e-2)" "unprognostic (1.63e-1)" "unprognostic (1.69e-1)" "unprognostic (1.43e-2)" "unprognostic (7.46e-3)" "unprognostic (1.96e-2)" "unprognostic (1.33e-2)" "unprognostic (2.56e-1)" "unprognostic (1.11e-1)" "unprognostic (3.07e-2)" "unprognostic (4.40e-2)" "unprognostic (1.40e-1)" "unprognostic (4.61e-4)" "unprognostic (2.79e-2)" "unprognostic (1.97e-1)" "unprognostic (3.61e-2)" "unprognostic (2.67e-3)" 0.2 1.5 2.3 0.2 7.0 0.0 0.3 0.9 10.3 0.2 0.1 0.0 0.0 0.0 0.1 2.6 0.0 0.0 0.1 9.7 1.9 0.0 0.0 0.0 1.0 1.4 2.6 0.1 0.1 0.2 0.0 0.0 1.3 0.2 0.0 0.3 0.3 0.1 0.9 32.6 0.0 0.0 0.6 0.1 0.1 0.8 2.0 0.3 0.0 0.5 1.0 0.8 0.3 2.5 0.0 0.0 24.1 0.4 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.3 0.1 0.0 23.9 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.1 0.0 1.4 5.7 0.0 0.1 0.0 28.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 7.0 0.9 10.3 9.7 1.9 1.4 2.6 1.3 0.6 2.0 2.5 12.2 0.0 0.0 2.3 8.3 27.3 2.9 1.4 20.5 7.8 9.9 39.1 5.2 0.0 0.2 0.0 22.9 0.2 13.4 13.8 0.0 0.0 0.2 0.5 2.3 1.9 1.8 2.7 6.4 0.0 0.1 5.2 7.1 1.4 0.0 0.5 0.0 0.0 0.3 1.7 1.1 11.0 0.0 0.0 1.3 0.0 0.3 4.3 7.2 1.0 0.0 14.0 0.0 0.5 0.2 0.0 0.1 0.0 2.7 0.7 0.3 0.1 0.0 21.1 0.0 8.5 7.2 0.2 4.1 20.2 55.8 0.1 5.2 8.3 5.7 3.2 PPARA "hPPAR, NR1C1, PPAR" ENSG00000186951 "Peroxisome proliferator activated receptor alpha" Q07869 22 46150521-46243756 "FDA approved drug targets, Metabolic proteins, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 44.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 99.4;Hepatocytes: 144.5;Proximal enterocytes: 93.2;Rod photoreceptor cells: 148.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "eosinophil: 10.3;plasmacytoid DC: 3.1" "Group enriched" "Detected in many" 5 "dendritic cells: 3.1;granulocytes: 10.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058901, HPA067049, CAB075701" Supported Enhanced Nucleoplasm NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 3: HMC-1 - Innate immune response" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm "CAB075701: , HPA058901: AB_2683849, HPA067049: AB_2685770" "unprognostic (1.96e-1)" "unprognostic (2.19e-1)" "unprognostic (1.02e-1)" "unprognostic (4.76e-2)" "unprognostic (3.94e-3)" "unprognostic (4.30e-2)" "unprognostic (1.24e-1)" "unprognostic (4.94e-2)" "unprognostic (2.95e-1)" "unprognostic (5.52e-3)" "unprognostic (4.50e-2)" "unprognostic (1.01e-1)" "prognostic favorable (4.39e-9)" "unprognostic (4.84e-2)" "unprognostic (2.76e-1)" "unprognostic (1.23e-1)" "unprognostic (3.18e-2)" 7.9 6.3 9.6 4.5 12.7 6.6 3.8 9.5 6.9 4.1 23.5 11.8 18.4 3.8 3.6 7.7 4.1 4.4 26.3 7.7 8.8 22.4 33.2 4.0 3.4 11.0 11.2 11.2 8.2 7.4 2.6 4.3 10.0 6.2 9.1 18.2 7.8 5.7 26.2 7.7 18.4 4.3 8.6 4.4 6.1 1.3 11.7 3.7 7.0 44.6 3.9 5.1 4.0 10.5 7.8 1.9 2.4 8.4 13.0 8.3 5.3 6.7 13.2 7.0 7.2 3.8 3.7 2.8 3.3 15.6 6.5 3.5 7.1 8.7 6.3 8.1 8.9 8.7 4.8 8.0 8.1 6.0 14.3 6.6 6.9 5.2 11.8 6.0 1.5 6.3 3.2 6.4 6.6 2.0 6.8 2.2 0.3 6.5 1.9 8.0 8.6 3.6 4.7 4.6 2.4 7.0 2.6 2.4 8.0 3.2 2.7 4.6 2.6 7.3 7.7 6.7 2.9 6.3 4.0 1.2 11.4 6.6 2.3 1.4 0.8 10.3 1.0 1.0 0.8 0.8 0.5 0.5 0.6 1.0 0.6 0.4 0.7 0.7 0.7 3.1 1.4 0.2 9.6 12.7 9.5 6.9 7.7 8.8 11.0 11.2 10.0 8.6 11.7 10.5 15.0 3.2 13.6 49.6 8.0 23.3 15.0 7.8 9.1 15.0 14.3 11.4 99.4 22.8 8.9 7.3 62.6 8.0 18.4 58.8 9.8 10.3 0.6 9.4 26.4 15.5 19.9 32.0 1.4 16.6 6.7 16.0 14.8 18.4 5.1 19.1 22.5 144.5 8.8 5.0 13.8 31.4 0.0 24.8 10.2 1.1 19.6 10.4 3.6 10.3 12.2 16.0 8.2 19.6 27.2 13.0 24.5 30.1 10.6 19.1 93.2 40.8 5.0 148.0 6.6 31.0 15.8 0.7 1.7 19.3 34.2 3.0 9.6 14.6 37.9 19.9 PPARGC1A "PGC-1alpha, PGC1, PGC1A, PPARGC1" ENSG00000109819 "PPARG coactivator 1 alpha" Q9UBK2 4 23755041-23904089 "Cancer-related genes, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" "Activator, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 44.6" "Group enriched" "Detected in many" 5 "Excitatory neurons: 1098.2;Inhibitory neurons: 1704.4;Oligodendrocyte precursor cells: 890.2" "Cancer enhanced" "Detected in many" "renal cancer: 7.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "A-431: 88.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063136 Supported Nucleoplasm NA NA "Cluster 8: Non-specific - Mitochondria" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA063136: AB_2684948" "unprognostic (1.08e-1)" "unprognostic (7.47e-2)" "unprognostic (6.85e-3)" "unprognostic (2.28e-6)" "unprognostic (5.00e-2)" "unprognostic (1.15e-1)" "prognostic favorable (3.35e-6)" "unprognostic (3.04e-1)" "unprognostic (1.79e-1)" "unprognostic (1.69e-1)" "unprognostic (6.77e-2)" "unprognostic (4.58e-2)" "prognostic favorable (1.49e-14)" "unprognostic (3.62e-2)" "unprognostic (2.31e-1)" "prognostic unfavorable (5.80e-4)" "unprognostic (3.07e-3)" 2.3 2.9 4.2 0.6 3.2 0.0 1.6 7.6 13.0 3.3 33.9 7.4 7.6 0.9 1.5 3.3 1.5 2.6 36.3 3.1 10.7 29.0 44.6 3.1 0.2 4.1 4.1 1.2 3.8 38.5 4.8 0.1 2.6 3.3 9.1 4.2 29.3 3.0 29.5 8.2 6.6 1.9 2.4 0.8 4.3 4.5 7.2 2.3 17.7 37.2 0.4 1.1 1.0 4.1 88.6 0.0 1.6 0.0 2.6 0.0 0.0 0.0 1.9 0.2 0.2 0.0 0.0 0.2 0.0 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.8 0.0 4.5 10.7 0.0 0.1 0.0 8.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.4 7.6 0.0 0.0 0.7 0.0 12.3 0.1 4.0 0.2 2.8 0.0 3.5 4.2 0.5 1.4 0.0 0.7 0.7 0.0 1.6 8.1 0.1 0.1 1.6 1.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 3.2 7.6 13.0 3.1 10.7 4.1 4.1 2.6 2.4 7.2 4.1 2.5 19.2 2.6 240.6 0.9 0.9 4.1 7.4 1.2 7.0 2.7 1.5 90.9 47.1 6.3 36.8 39.6 0.0 0.0 36.0 52.8 12.0 78.3 7.2 1.3 0.8 26.7 0.0 1098.2 0.0 0.0 2.4 4.1 9.7 1.3 0.2 1.1 88.8 0.0 0.0 1704.4 17.0 38.7 2.5 0.3 69.7 0.9 0.6 7.2 24.4 0.1 6.4 0.0 890.2 28.8 0.6 7.3 2.2 1.8 1.4 32.0 26.8 4.8 1.9 0.0 37.1 5.1 0.8 0.6 2.6 1.1 0.0 1.0 1.9 21.9 1.5 PPIF "Cyp-D, hCyP3" ENSG00000108179 "Peptidylprolyl isomerase F" P30405 10 79347469-79355334 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Necrosis" "Isomerase, Rotamase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 370.9;Macrophages: 160.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 75.0" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077416 Supported Mitochondria NA NA 320000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 1: K-562 - Erythropoiesis" "Cluster 41: Macrophages - Immune response" Mitochondria "HPA077416: AB_2686840" "unprognostic (2.21e-1)" "unprognostic (5.48e-2)" "unprognostic (1.68e-1)" "unprognostic (1.72e-3)" "unprognostic (1.69e-1)" "unprognostic (3.16e-3)" "unprognostic (3.45e-1)" "unprognostic (4.33e-3)" "unprognostic (1.66e-1)" "unprognostic (1.97e-1)" "unprognostic (2.82e-1)" "unprognostic (9.37e-3)" "unprognostic (1.02e-3)" "unprognostic (1.23e-1)" "unprognostic (1.66e-1)" "unprognostic (1.69e-3)" "unprognostic (4.88e-2)" 62.7 227.7 42.7 42.8 48.4 168.8 42.4 57.9 69.6 27.6 63.7 50.0 36.3 14.0 7.2 66.0 22.9 19.5 119.1 38.1 45.2 63.3 174.9 29.1 32.3 49.0 56.2 19.3 86.9 77.6 18.3 27.1 48.8 18.8 52.4 8.9 39.5 45.5 99.5 71.9 31.3 21.0 50.6 58.7 98.2 35.0 57.1 28.3 26.0 133.6 55.5 60.0 35.1 60.8 220.4 90.6 62.3 123.5 57.0 73.6 79.8 124.2 161.2 265.7 249.6 213.5 102.7 224.8 68.0 87.4 188.6 127.8 195.3 115.4 410.5 72.2 186.4 352.8 87.5 380.7 96.4 245.7 80.4 173.2 81.3 264.5 262.3 86.5 47.5 86.4 351.6 268.3 91.6 111.7 64.1 204.2 53.0 99.6 500.6 109.8 96.4 114.7 103.9 200.0 124.1 92.0 63.6 253.8 97.9 40.5 111.4 187.2 43.5 116.1 106.3 137.9 242.0 124.7 137.7 181.9 114.5 313.9 32.0 15.2 34.3 18.0 10.4 27.5 10.9 19.1 9.1 9.6 43.3 7.7 8.1 7.9 75.0 9.0 10.4 5.4 10.0 16.6 42.7 48.4 57.9 69.6 38.1 45.2 49.0 56.2 48.8 50.6 57.1 60.8 8.4 6.4 6.8 7.2 32.7 42.6 30.2 23.8 31.3 4.0 41.8 40.8 124.6 14.3 14.4 12.9 6.2 99.4 26.4 39.9 92.0 42.1 14.5 12.4 24.0 10.1 21.6 37.0 4.1 28.0 127.1 25.1 78.0 15.5 13.4 73.4 6.1 98.5 91.1 8.4 5.7 69.5 18.3 40.3 370.9 14.1 6.2 160.8 35.6 4.7 32.0 13.0 5.2 5.5 15.0 39.8 26.6 6.0 48.7 41.4 21.3 41.2 12.6 5.2 19.7 18.2 28.6 14.8 22.5 52.9 37.6 142.3 23.9 60.2 81.1 34.2 PPM1J "DKFZp434P1514, FLJ35951, MGC19531, PP2Czeta, PPP2CZ" ENSG00000155367 "Protein phosphatase, Mg2+/Mn2+ dependent 1J" Q5JR12 1 112709994-112715477 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "epididymis: 18.8;skeletal muscle: 68.4;skin 1: 18.1;testis: 63.8;tongue: 25.6" "Group enriched" "Detected in many" 4 "Early spermatids: 123.6;Late spermatids: 281.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 10 "plasmacytoid DC: 67.9" "Lineage enriched" "Detected in many" 15 "dendritic cells: 67.9" "Cell line enhanced" "Detected in many" "T-47d: 19.5" "Region enriched" "Detected in many" 7 "olfactory bulb: 27.3" "Low region specificity" "Detected in all" HPA046045 Uncertain Approved Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 6: T47d - Mammary gland" "Cluster 34: Spermatids - Unknown function" Vesicles "HPA046045: AB_2679516" "unprognostic (8.68e-2)" "unprognostic (5.65e-2)" "unprognostic (3.29e-2)" "unprognostic (2.59e-1)" "unprognostic (2.93e-3)" "unprognostic (2.34e-2)" "unprognostic (3.55e-2)" "unprognostic (3.74e-2)" "unprognostic (2.55e-1)" "unprognostic (9.30e-3)" "unprognostic (3.36e-2)" "unprognostic (7.22e-2)" "unprognostic (1.80e-2)" "unprognostic (1.27e-2)" "unprognostic (1.46e-1)" "unprognostic (2.28e-2)" "unprognostic (9.96e-4)" 1.1 2.6 6.3 1.0 6.6 0.7 2.2 5.9 6.5 2.3 3.8 1.2 0.6 1.9 18.8 4.6 2.8 1.0 8.7 5.8 5.7 7.8 0.7 1.6 3.3 5.2 7.8 2.3 1.7 5.5 2.6 0.5 4.6 3.3 0.6 6.9 2.8 2.1 68.4 18.1 1.4 1.3 4.5 1.4 1.2 63.8 9.1 2.3 3.1 25.6 2.2 1.1 4.0 3.9 2.7 0.1 1.5 1.7 0.8 1.5 1.1 0.3 0.7 0.3 1.0 1.2 0.8 0.4 0.4 0.8 0.8 4.9 1.1 4.6 0.4 0.0 2.6 0.8 0.2 0.2 0.9 0.0 0.2 1.7 3.0 0.9 4.6 1.0 2.1 0.2 1.0 0.0 1.2 2.9 0.0 0.0 1.6 1.4 2.3 0.1 0.1 0.0 2.7 0.1 0.8 0.2 0.6 4.3 1.3 2.2 19.5 0.0 1.1 0.3 2.8 0.0 0.2 0.1 0.0 0.0 2.3 0.6 2.6 0.0 0.3 0.0 0.0 1.5 0.1 0.7 0.0 0.1 7.1 0.7 0.0 0.0 0.0 0.0 4.3 67.9 0.0 0.8 6.3 6.6 5.9 6.5 5.8 5.7 5.2 7.8 4.6 4.5 9.1 3.9 1.2 0.0 0.5 0.3 2.0 2.2 4.7 8.7 10.2 5.7 4.2 4.6 5.8 0.0 2.7 1.8 10.4 1.0 41.3 0.7 9.8 3.2 123.6 3.2 0.3 1.5 0.0 0.0 1.8 4.3 1.4 1.1 1.1 0.6 0.0 5.6 0.7 0.1 0.7 0.0 1.5 0.9 2.0 1.3 11.5 281.6 3.1 2.0 0.0 0.0 1.6 25.4 0.0 0.0 0.2 2.1 2.4 2.6 0.0 6.7 0.3 0.6 1.8 9.1 6.6 1.1 2.8 2.8 16.9 3.5 2.8 0.5 0.9 3.2 0.8 2.9 PPP1R13L "IASPP, RAI" ENSG00000104881 "Protein phosphatase 1 regulatory subunit 13 like" Q8WUF5 19 45379638-45406349 "Predicted intracellular proteins, Transcription factors" "Apoptosis, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 179.4;heart muscle: 139.4;skin 1: 219.8" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 85.6;Granulosa cells: 118.3;Syncytiotrophoblasts: 128.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "HBEC3-KT: 130.1;hTCEpi: 189.0;hTERT-HME1: 131.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB005016, HPA041231, HPA059883" Approved Enhanced Cytosol NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 40: Granulosa cells - Unknown function" Cytosol "CAB005016: AB_2168576, HPA041231: AB_2677376, HPA059883: AB_2684151" "unprognostic (1.87e-1)" "unprognostic (1.78e-1)" "unprognostic (7.46e-2)" "unprognostic (2.92e-1)" "unprognostic (3.74e-1)" "unprognostic (2.06e-2)" "unprognostic (1.31e-3)" "prognostic unfavorable (3.39e-5)" "unprognostic (1.77e-1)" "prognostic unfavorable (5.40e-4)" "unprognostic (2.52e-3)" "unprognostic (1.92e-2)" "unprognostic (1.55e-3)" "unprognostic (1.34e-1)" "unprognostic (7.69e-2)" "unprognostic (8.87e-2)" "unprognostic (1.02e-1)" 20.4 20.1 11.7 2.9 11.7 0.6 29.6 11.5 14.0 44.9 9.5 11.1 5.0 8.2 15.2 179.4 9.6 6.0 139.4 10.8 14.3 24.8 12.6 20.3 2.6 11.9 11.1 8.8 31.5 12.2 11.8 26.6 11.7 30.8 6.8 13.6 55.6 13.3 5.8 219.8 9.1 5.4 10.0 6.4 12.0 3.1 12.7 4.0 17.7 4.4 18.8 23.6 84.9 12.4 72.3 10.7 4.6 3.8 4.7 2.9 61.5 14.5 2.5 17.5 24.3 23.1 70.6 9.5 5.9 11.9 36.5 97.2 4.0 130.1 16.0 24.0 5.9 1.4 36.3 8.7 10.0 1.0 3.4 4.0 189.0 27.9 131.9 79.2 33.2 7.9 8.1 3.6 1.2 64.7 1.8 1.9 5.3 36.9 18.3 7.4 5.6 1.7 22.9 95.0 2.4 7.6 64.5 68.4 1.6 30.0 58.2 1.9 46.3 23.1 60.9 1.8 76.2 35.1 42.1 6.5 3.3 2.9 5.6 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.2 0.0 11.7 11.7 11.5 14.0 10.8 14.3 11.9 11.1 11.7 10.0 12.7 12.4 14.3 35.3 13.0 9.4 2.0 68.7 85.6 38.4 67.2 1.7 21.9 28.6 38.8 20.0 27.8 20.2 10.4 83.2 2.5 17.8 5.9 34.9 0.7 8.7 3.0 13.4 7.2 10.1 0.8 15.8 37.7 5.6 8.6 17.1 4.5 118.3 11.7 2.5 7.6 0.0 0.9 6.9 14.2 1.6 5.0 0.5 5.9 2.2 12.4 9.4 1.9 2.4 2.1 2.5 1.6 50.4 17.2 12.4 6.1 44.2 22.6 3.9 16.3 26.8 6.6 8.4 14.1 2.7 2.1 81.2 71.0 128.5 2.5 2.8 9.0 63.4 PPP1R1C Inhibitor-1-like ENSG00000150722 "Protein phosphatase 1 regulatory inhibitor subunit 1C" Q8WVI7 2 181954241-182131398 "Predicted intracellular proteins" "Cell cycle, Cell division" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "heart muscle: 21.1" "Group enriched" "Detected in many" 4 "Early spermatids: 168.5;Late spermatids: 219.8;Spermatocytes: 145.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA055043 Approved "Nucleoplasm,Nucleoli,Golgi apparatus" NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "Nucleoli, Golgi apparatus" "HPA055043: AB_2797251" "unprognostic (1.70e-1)" "unprognostic (3.15e-1)" "unprognostic (4.54e-3)" "unprognostic (1.08e-2)" "unprognostic (1.36e-1)" "unprognostic (1.01e-1)" "unprognostic (2.44e-2)" "unprognostic (3.77e-2)" "unprognostic (6.57e-2)" "unprognostic (6.59e-3)" "unprognostic (1.13e-1)" "unprognostic (7.98e-2)" "unprognostic (3.70e-2)" "unprognostic (1.00e-3)" "unprognostic (7.68e-2)" "unprognostic (3.07e-2)" "unprognostic (9.75e-3)" 0.0 0.0 0.2 0.0 0.3 0.0 0.0 1.4 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.2 21.1 0.3 1.0 0.0 0.8 0.1 0.0 0.7 0.8 0.0 0.3 0.0 0.4 0.0 1.4 1.0 0.0 1.8 0.0 0.0 3.7 0.1 0.0 0.0 0.1 0.0 0.2 0.3 0.1 0.7 0.0 3.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 1.4 0.4 0.3 1.0 0.7 0.8 1.4 0.1 0.1 0.3 0.1 12.8 8.7 6.2 0.0 0.3 0.6 1.2 2.8 1.1 0.3 0.3 40.6 17.2 8.1 3.7 0.0 3.1 0.0 0.5 1.9 2.5 168.5 1.7 0.1 0.6 6.1 0.0 1.1 11.0 6.6 2.4 4.6 0.8 0.0 0.0 0.0 18.5 0.6 0.0 19.4 0.4 10.2 0.8 0.0 219.8 5.9 0.3 3.6 1.9 3.6 12.0 0.0 3.5 0.7 23.1 0.1 0.7 0.0 0.3 0.0 0.7 1.6 1.7 0.0 0.4 0.8 145.1 2.6 1.3 0.3 2.5 0.0 0.8 0.6 1.0 PPP2R2C "B55gamma, IMYPNO, MGC33570, PR52, PR55G" ENSG00000074211 "Protein phosphatase 2 regulatory subunit Bgamma" Q9Y2T4 4 6320578-6563600 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 106.2" "Group enriched" "Detected in many" 5 "Astrocytes: 61.0;Early spermatids: 67.4;Excitatory neurons: 203.3;Inhibitory neurons: 82.8;Late spermatids: 182.5;Oligodendrocytes: 94.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 10.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 31.4;A549: 46.1;CAPAN-2: 28.2;GAMG: 68.4;MCF7: 36.2;PC-3: 38.9;SCLC-21H: 39.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042122, HPA042770, HPA060473" Approved Approved Cytosol NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA042122: AB_2677859, HPA042770: AB_2678155, HPA060473: AB_2684291" "unprognostic (9.39e-2)" "unprognostic (7.10e-2)" "unprognostic (9.12e-2)" "unprognostic (1.14e-3)" "unprognostic (1.48e-1)" "unprognostic (5.91e-2)" "unprognostic (2.70e-4)" "prognostic unfavorable (4.94e-4)" "unprognostic (1.77e-1)" "unprognostic (3.90e-1)" "unprognostic (4.67e-2)" "unprognostic (2.77e-1)" "unprognostic (1.36e-13)" "unprognostic (2.52e-1)" "unprognostic (3.92e-2)" "unprognostic (2.66e-3)" "unprognostic (9.90e-3)" 0.8 6.2 72.9 0.6 86.7 0.0 1.4 42.1 106.2 18.0 0.0 1.1 0.8 27.0 7.4 35.9 9.9 0.4 2.5 85.7 44.5 0.3 0.1 0.1 0.3 52.5 52.7 0.6 0.7 1.5 22.6 0.1 55.1 5.0 0.3 10.9 5.3 14.5 0.8 34.0 1.2 11.9 62.3 0.3 0.8 7.3 66.9 2.7 0.1 0.9 3.1 0.9 11.5 91.2 31.4 46.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 28.2 0.0 19.0 0.0 68.4 13.7 20.0 0.7 0.0 0.0 2.4 0.0 3.2 3.7 0.7 0.0 0.1 6.6 11.4 0.0 0.0 0.0 0.1 4.2 0.0 0.1 6.6 36.2 0.0 0.1 2.2 0.6 38.9 0.0 0.0 1.2 0.0 0.1 39.1 7.5 1.5 0.1 0.0 1.1 18.9 0.1 0.0 0.2 22.7 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 72.9 86.7 42.1 106.2 85.7 44.5 52.5 52.7 55.1 62.3 66.9 91.2 0.2 0.0 0.0 61.0 0.0 14.7 0.4 0.8 4.6 11.0 1.9 0.4 4.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 67.4 0.8 5.7 0.6 0.0 0.0 203.3 0.2 0.0 0.2 0.0 2.4 0.0 0.0 0.0 0.0 0.1 3.3 82.8 0.0 0.0 0.0 1.1 182.5 6.8 0.0 0.0 4.7 0.0 6.5 0.0 14.1 94.6 2.4 0.0 4.5 0.0 1.3 0.0 0.2 0.0 3.1 0.0 0.0 2.5 2.3 1.6 6.5 22.0 0.0 0.2 0.1 0.0 0.2 PPP2R3A "PPP2R3, PR130, PR72" ENSG00000073711 "Protein phosphatase 2 regulatory subunit B''alpha" Q06190 3 135965728-136147894 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "heart muscle: 51.2;skeletal muscle: 180.5;tongue: 117.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 115.3;Oligodendrocytes: 201.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 37.4;BJ hTERT+: 35.3;RPTEC TERT1: 46.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035829, HPA035830, HPA065338" Uncertain Approved "Golgi apparatus" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Golgi apparatus" "HPA035829: AB_10696513, HPA035830: AB_10670121, HPA065338: AB_2685475" "unprognostic (3.35e-1)" "unprognostic (2.37e-2)" "unprognostic (1.71e-1)" "prognostic unfavorable (4.38e-4)" "unprognostic (1.71e-1)" "unprognostic (4.04e-1)" "unprognostic (1.44e-4)" "unprognostic (9.43e-2)" "unprognostic (1.27e-1)" "unprognostic (5.70e-2)" "prognostic unfavorable (1.14e-5)" "unprognostic (8.92e-2)" "prognostic favorable (1.15e-5)" "unprognostic (4.55e-2)" "unprognostic (3.06e-2)" "unprognostic (1.01e-1)" "prognostic unfavorable (3.91e-4)" 3.1 3.4 3.3 2.3 7.2 0.2 7.1 4.3 5.0 5.2 3.9 8.0 2.0 7.7 5.1 8.3 4.1 5.0 51.2 4.2 4.9 22.0 1.1 3.9 0.6 5.7 5.5 5.6 3.4 11.7 1.8 2.8 5.3 5.9 5.4 2.6 8.9 6.5 180.5 18.9 2.3 9.6 4.3 1.1 7.4 7.2 6.0 0.6 3.1 117.6 1.2 4.5 4.0 13.7 37.4 2.0 10.3 5.0 8.1 10.2 11.9 28.5 35.3 13.2 16.3 2.4 2.4 0.1 10.7 29.3 9.5 4.7 4.3 10.0 28.3 0.1 1.4 1.6 1.0 0.1 5.8 0.0 1.4 9.3 8.5 16.8 7.8 13.3 12.8 1.0 1.0 0.1 19.2 6.2 0.3 0.2 7.2 0.4 6.9 0.1 15.1 0.1 46.2 1.4 0.7 5.7 4.7 5.7 10.9 9.2 9.1 0.5 8.4 13.7 7.5 18.8 12.7 0.4 1.0 0.1 10.1 0.8 4.9 0.1 0.1 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.2 0.1 0.0 3.3 7.2 4.3 5.0 4.2 4.9 5.7 5.5 5.3 4.3 6.0 13.7 7.9 28.9 27.6 51.6 2.8 26.4 19.5 7.1 19.4 5.7 19.9 15.5 115.3 8.6 10.0 55.2 0.0 10.9 6.7 25.3 21.5 20.6 8.4 9.9 19.0 11.4 13.1 0.4 35.2 9.9 15.4 14.8 21.9 16.1 3.8 15.7 8.6 2.9 2.5 3.3 47.2 6.9 6.1 2.4 9.8 10.7 24.5 3.2 28.4 13.1 9.6 8.9 2.1 72.4 201.1 17.2 10.6 18.4 1.5 17.8 21.7 40.1 8.1 2.6 6.6 29.0 14.0 10.1 18.6 15.3 33.2 10.4 3.4 6.7 8.9 15.6 PRC1 ASE1 ENSG00000198901 "Protein regulator of cytokinesis 1" O43663 15 90966040-90995629 "Predicted intracellular proteins" "Cell cycle, Cell division" Oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 89.9;testis: 55.0" "Cell type enhanced" "Detected in many" "Erythroid cells: 142.9;Extravillous trophoblasts: 68.3;Spermatocytes: 136.4;Spermatogonia: 74.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 34.4" "Lineage enriched" "Detected in many" 4 "granulocytes: 34.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA034521, HPA048816" Enhanced Supported "Nucleoplasm,Plasma membrane,Microtubules,Cytokinetic bridge,Midbody" Yes Yes "Cluster 38: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Microtubules, Cytokinetic bridge, Midbody" Nucleoplasm "HPA034521: AB_10670169, HPA048816: " "unprognostic (1.14e-1)" "unprognostic (3.98e-2)" "unprognostic (9.21e-2)" "unprognostic (1.75e-3)" "unprognostic (2.39e-1)" "unprognostic (3.43e-2)" "prognostic unfavorable (2.11e-4)" "unprognostic (1.24e-3)" "unprognostic (3.86e-3)" "unprognostic (1.65e-2)" "prognostic unfavorable (2.76e-5)" "unprognostic (2.49e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.09e-2)" "unprognostic (1.79e-1)" "unprognostic (7.90e-2)" "unprognostic (3.92e-2)" 7.4 6.2 6.4 10.0 6.1 89.9 6.4 10.3 8.4 8.1 5.0 16.3 10.6 5.7 2.3 37.6 6.0 3.0 6.9 5.6 4.9 5.6 4.8 9.0 16.9 4.8 5.2 8.1 8.9 2.6 3.6 15.3 5.2 4.9 16.5 4.9 9.5 1.5 4.1 20.1 13.0 9.4 4.9 12.5 11.7 55.0 4.2 43.0 4.3 2.3 24.9 4.8 13.7 5.6 167.9 199.9 164.8 113.6 16.8 28.7 87.5 237.8 139.3 257.2 195.3 134.6 158.5 65.5 91.4 151.9 156.9 220.9 188.8 101.2 240.6 118.7 206.4 135.6 263.5 123.5 4.1 71.4 109.0 7.7 12.8 145.8 146.9 56.6 146.4 100.5 114.0 132.4 241.1 144.4 66.9 98.5 66.6 216.4 84.9 69.7 205.1 86.3 115.3 123.6 151.2 118.9 225.4 121.9 82.7 112.3 149.1 127.1 91.2 168.2 146.0 140.5 345.1 43.5 127.7 80.0 74.5 162.0 265.3 34.4 0.6 2.9 0.6 0.1 0.4 1.1 1.3 1.3 2.4 0.5 1.2 0.4 0.4 3.0 0.3 2.6 8.0 1.0 6.4 6.1 10.3 8.4 5.6 4.9 4.8 5.2 5.2 4.9 4.2 5.6 2.5 0.0 3.1 1.3 6.8 16.6 6.6 8.0 2.2 6.4 3.4 4.3 3.2 0.0 7.6 3.7 0.0 45.5 2.8 16.5 0.0 3.2 41.5 4.5 4.0 4.7 5.4 142.9 5.0 2.9 68.3 7.2 16.3 6.8 8.9 13.2 9.3 2.1 21.5 3.3 5.2 17.0 10.2 8.7 15.0 15.4 3.7 5.2 3.6 1.9 5.5 3.8 4.1 2.0 1.7 2.3 3.2 1.9 17.5 5.9 2.0 0.1 3.2 4.6 6.6 7.4 10.9 136.4 74.2 38.0 14.2 14.6 6.8 0.4 24.1 6.7 PRICKLE3 LMO6 ENSG00000012211 "Prickle planar cell polarity protein 3" O43900 X 49174802-49186528 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Developmental protein" "Disease variant, Leber hereditary optic neuropathy, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Early spermatids: 60.8;Late spermatids: 100.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA000998 Uncertain NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 31: Spermatids - Spermatogenesis" "HPA000998: AB_1079258" "unprognostic (9.83e-3)" "unprognostic (7.02e-2)" "unprognostic (6.97e-3)" "unprognostic (2.54e-1)" "unprognostic (1.12e-2)" "unprognostic (5.61e-2)" "unprognostic (2.53e-2)" "unprognostic (2.55e-1)" "unprognostic (1.89e-1)" "unprognostic (2.41e-2)" "unprognostic (3.78e-2)" "unprognostic (1.14e-3)" "prognostic unfavorable (5.73e-6)" "unprognostic (2.28e-3)" "unprognostic (1.74e-1)" "unprognostic (1.52e-1)" "prognostic favorable (4.84e-5)" 4.3 3.8 2.3 3.5 2.5 2.1 4.0 2.5 2.9 4.8 4.2 3.7 3.0 4.0 1.7 10.2 4.7 2.9 5.7 2.1 2.4 2.5 3.1 4.0 3.3 2.7 2.7 2.6 5.1 4.0 2.1 3.8 2.7 4.6 3.0 0.6 4.5 5.8 11.6 12.0 3.5 3.3 2.9 3.8 4.0 1.1 2.7 3.4 3.9 10.5 4.5 5.1 6.6 3.0 17.7 20.3 0.5 1.7 8.4 9.1 19.0 6.8 10.2 5.1 7.9 6.2 10.9 0.0 6.1 8.4 1.6 24.8 15.6 25.1 2.3 21.9 8.4 7.4 12.2 4.7 12.2 5.0 24.3 8.3 19.3 6.4 15.7 3.3 5.3 4.5 12.4 6.6 8.6 27.8 6.0 7.4 3.0 10.6 21.7 8.3 5.3 9.8 6.7 24.7 3.4 0.0 9.4 8.6 6.7 6.0 17.4 5.6 6.2 0.1 8.0 7.2 2.6 11.6 8.3 4.1 8.0 6.6 0.1 2.4 8.3 9.2 2.3 9.1 3.2 7.0 3.1 3.8 7.5 4.1 2.5 2.6 4.7 3.0 12.1 3.5 4.2 5.1 2.3 2.5 2.5 2.9 2.1 2.4 2.7 2.7 2.7 2.9 2.7 3.0 2.7 0.0 1.5 1.0 4.2 15.2 5.5 13.7 10.8 0.3 1.4 2.2 1.5 0.0 6.6 1.8 2.1 3.2 1.0 1.9 1.9 3.4 60.8 2.7 2.0 3.2 1.2 2.5 0.2 2.7 6.8 2.8 6.6 2.4 0.0 1.7 1.4 1.4 2.5 0.0 0.1 3.3 8.2 1.3 8.1 100.8 1.5 2.8 8.8 0.0 2.9 0.9 1.0 2.0 1.0 2.2 2.7 0.7 3.2 4.8 1.7 2.0 3.3 0.2 0.0 1.5 2.6 0.4 0.5 15.9 19.0 3.3 2.2 2.2 2.5 4.6 PRIM2 PRIM2A ENSG00000146143 "DNA primase subunit 2" P49643 6 57314805-57646850 "Plasma proteins, Predicted intracellular proteins" "DNA replication" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "prostate: 30.6" "Cell type enhanced" "Detected in many" "Microglial cells: 70.3;Oligodendrocyte precursor cells: 56.8;Oligodendrocytes: 54.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046566 Supported Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA046566: AB_2679701" "unprognostic (1.24e-1)" "unprognostic (1.55e-2)" "unprognostic (2.66e-2)" "prognostic unfavorable (6.98e-4)" "unprognostic (3.08e-1)" "unprognostic (6.24e-2)" "prognostic unfavorable (3.44e-5)" "unprognostic (2.31e-1)" "unprognostic (1.00e-2)" "prognostic favorable (3.00e-5)" "prognostic unfavorable (5.25e-4)" "unprognostic (3.89e-1)" "prognostic unfavorable (7.34e-6)" "unprognostic (2.04e-2)" "unprognostic (2.07e-1)" "unprognostic (1.67e-1)" "unprognostic (1.08e-1)" 4.3 3.3 3.9 6.6 4.6 15.0 6.9 6.0 4.3 5.6 6.9 6.9 6.0 7.2 6.9 4.3 6.2 4.3 3.3 3.9 5.6 3.9 5.0 4.8 10.6 4.2 4.7 7.2 4.0 3.9 1.9 7.5 4.4 30.6 8.4 4.0 4.2 5.6 2.3 5.8 5.2 8.0 2.8 5.5 4.8 6.5 4.5 15.3 4.4 2.4 11.8 5.8 4.1 7.1 44.8 17.7 34.1 37.6 16.8 29.5 27.3 53.1 48.8 57.0 74.7 26.6 21.1 39.4 27.7 66.6 39.6 27.9 30.2 29.2 71.6 35.1 24.2 47.6 22.7 43.0 7.3 43.5 27.4 12.1 12.0 61.0 20.3 14.2 26.9 44.1 46.2 38.9 48.3 28.2 49.8 37.6 22.0 37.1 17.2 34.7 46.9 31.2 21.0 20.7 24.5 19.2 31.5 15.9 21.3 38.9 33.3 47.4 17.9 54.7 55.5 106.2 44.2 14.4 29.3 47.2 26.6 50.5 30.4 0.7 1.9 1.8 4.1 3.7 4.3 3.5 3.5 5.4 3.0 4.0 2.8 5.7 1.4 5.2 4.2 5.1 4.7 2.1 3.9 4.6 6.0 4.3 3.9 5.6 4.2 4.7 4.4 2.8 4.5 7.1 5.9 0.0 2.7 30.0 11.2 4.0 6.7 4.1 11.4 5.6 6.2 4.2 1.1 2.8 4.6 3.7 12.5 17.0 15.1 4.3 3.9 5.1 10.3 4.9 7.1 5.0 1.2 26.5 38.0 5.2 22.0 6.9 4.1 6.0 12.0 13.7 4.2 3.5 9.3 6.7 32.6 6.5 10.2 6.6 6.4 3.7 6.5 7.0 0.0 70.3 7.3 4.8 17.5 56.8 54.5 4.9 5.3 6.8 12.7 7.1 4.4 1.8 4.1 5.6 19.7 4.9 6.8 10.1 11.2 8.7 3.0 5.7 13.6 8.0 8.6 5.3 PRKCQ ENSG00000065675 "Protein kinase C theta" Q04759 10 6427143-6580301 "Cancer-related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Immunity, Inflammatory response" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "lymphoid tissue: 33.6;skeletal muscle: 124.5;tongue: 112.6" "Cell type enhanced" "Detected in many" "Astrocytes: 22.9;dendritic cells: 22.4;NK-cells: 32.0;Oligodendrocyte precursor cells: 24.6;Oligodendrocytes: 75.2;T-cells: 31.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "gdT-cell: 23.0;MAIT T-cell: 18.0;memory CD4 T-cell: 24.5;memory CD8 T-cell: 24.5;naive CD4 T-cell: 19.1;naive CD8 T-cell: 17.9;NK-cell: 13.3;T-reg: 39.7" "Group enriched" "Detected in many" 11 "NK-cells: 13.3;T-cells: 39.7" "Cell line enhanced" "Detected in many" "HEL: 57.8;JURKAT: 40.0;MOLT-4: 43.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065279, HPA073098" Enhanced "Centriolar satellite" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Centriolar satellite" "HPA065279: AB_2685453, HPA073098: AB_2686571" "unprognostic (6.61e-3)" "unprognostic (2.12e-1)" "unprognostic (1.87e-1)" "unprognostic (1.48e-1)" "unprognostic (1.50e-1)" "unprognostic (2.24e-1)" "unprognostic (2.69e-3)" "unprognostic (2.46e-1)" "unprognostic (8.40e-2)" "unprognostic (2.66e-1)" "unprognostic (1.17e-1)" "unprognostic (3.22e-1)" "unprognostic (5.26e-2)" "unprognostic (7.74e-2)" "unprognostic (2.79e-1)" "prognostic unfavorable (5.27e-4)" "unprognostic (3.51e-2)" 0.8 0.7 5.3 5.2 8.5 5.7 0.9 6.1 6.3 1.6 12.1 1.4 1.5 2.5 8.3 2.2 3.9 1.5 0.3 5.5 8.2 10.9 1.0 5.3 12.3 6.5 8.6 1.3 3.4 0.7 0.8 0.2 6.4 1.8 1.7 1.5 1.4 1.1 124.5 0.3 3.3 0.7 5.5 5.0 2.1 1.1 7.2 33.6 14.9 112.6 9.4 2.2 0.6 9.8 0.1 5.3 0.1 0.0 0.0 0.0 1.6 0.0 0.0 0.2 0.2 0.4 3.4 0.3 0.0 0.0 0.0 0.0 3.3 6.0 0.0 0.0 3.9 57.8 0.0 0.4 0.7 2.8 0.6 0.3 3.5 0.1 0.2 0.0 0.5 40.0 12.8 0.1 0.0 0.0 43.9 8.0 5.8 0.5 0.0 8.5 1.3 0.0 11.6 2.9 0.4 2.1 0.0 0.0 0.0 3.4 0.0 5.8 0.0 0.0 5.6 0.0 0.0 0.1 0.0 0.0 0.0 7.1 0.0 2.4 0.1 0.3 23.0 0.4 18.0 0.1 24.5 24.5 0.2 0.0 19.1 17.9 1.6 13.3 0.0 0.0 39.7 10.5 5.3 8.5 6.1 6.3 5.5 8.2 6.5 8.6 6.4 5.5 7.2 9.8 0.2 3.2 7.0 22.9 0.8 0.0 0.3 0.3 0.6 1.6 0.3 0.3 0.4 0.0 0.7 1.8 0.0 0.0 22.4 0.0 7.9 0.3 2.1 0.5 1.2 0.2 1.8 8.0 13.7 0.8 0.1 0.7 1.5 3.0 1.3 8.2 1.1 0.0 0.5 0.0 14.7 0.5 0.0 1.3 0.5 5.6 0.0 1.7 0.0 7.5 0.8 1.2 32.0 24.6 75.2 0.1 0.1 0.0 10.2 0.2 0.0 0.3 0.9 0.4 0.0 4.2 0.4 1.0 2.2 0.5 0.0 0.0 31.7 0.3 0.4 0.1 PROM1 "AC133, CD133, CORD12, MCDR2, PROML1, RP41, STGD4" ENSG00000007062 "Prominin 1" O43490 4 15963076-16084378 "CD markers, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cone-rod dystrophy, Disease variant, Retinitis pigmentosa, Stargardt disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "retina: 272.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 581.7;Respiratory ciliated cells: 144.8;Rod photoreceptor cells: 311.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 37.2;CACO-2: 70.6;CAPAN-2: 28.9;EFO-21: 62.2;NTERA-2: 97.4;RPTEC TERT1: 91.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA004922, CAB011525, HPA031053" Enhanced NA NA "Cluster 79: Retina - Phototransduction" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 9: Photoreceptor cells - Phototransduction" "CAB011525: AB_470302, HPA004922: AB_1846238, HPA031053: AB_2673713" "unprognostic (6.33e-2)" "unprognostic (2.54e-1)" "unprognostic (1.53e-1)" "unprognostic (3.39e-1)" "unprognostic (2.81e-1)" "unprognostic (2.16e-1)" "unprognostic (2.39e-1)" "unprognostic (6.64e-2)" "unprognostic (2.18e-2)" "unprognostic (2.17e-1)" "unprognostic (1.21e-2)" "unprognostic (9.06e-2)" "prognostic favorable (2.56e-5)" "unprognostic (2.16e-2)" "unprognostic (1.02e-1)" "unprognostic (9.38e-2)" "unprognostic (1.17e-1)" 0.3 0.3 4.1 6.2 3.0 4.0 27.7 2.7 3.5 44.9 2.0 30.7 12.4 6.0 4.3 5.1 5.4 30.9 6.7 3.3 2.8 20.9 1.8 3.1 0.0 3.8 4.3 0.1 14.4 0.0 0.1 30.1 3.6 2.8 16.7 272.9 57.9 7.1 1.0 0.9 22.9 3.5 2.8 0.2 24.8 8.0 5.0 0.1 4.8 0.0 0.1 4.2 0.2 3.1 0.0 0.0 37.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 70.6 28.9 0.6 62.2 0.0 0.0 0.1 7.3 0.0 0.1 0.3 0.0 0.0 0.0 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 97.4 0.0 0.0 1.4 0.1 0.0 91.1 0.1 12.0 3.6 0.0 2.4 1.9 3.5 0.6 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 3.0 2.7 3.5 3.3 2.8 3.8 4.3 3.6 2.8 5.0 3.1 0.2 3.2 4.8 1.3 0.3 0.0 0.1 7.2 0.0 14.8 38.2 30.0 8.6 31.5 29.9 82.8 581.7 0.6 1.0 39.3 0.0 64.1 31.4 71.1 1.7 5.1 44.4 2.1 0.9 15.5 0.1 4.4 31.6 14.8 0.0 3.8 0.7 0.1 0.1 10.1 5.4 15.0 34.6 0.0 0.0 44.3 3.1 0.7 0.0 27.2 0.6 47.5 0.0 45.8 1.2 38.2 28.3 6.4 0.4 1.5 18.8 3.6 144.8 311.3 0.0 0.8 3.1 2.1 1.0 0.7 0.0 0.1 0.7 0.3 26.0 4.1 PROSER1 "bA50D16.2, C13orf23, FLJ12661" ENSG00000120685 "Proline and serine rich 1" Q86XN7 13 39009865-39038089 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034225, HPA055687" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" Nucleoplasm Cytosol "CAB034225: AB_1564157, HPA055687: AB_2682886" "unprognostic (6.75e-3)" "unprognostic (9.56e-3)" "unprognostic (1.33e-1)" "unprognostic (3.81e-2)" "unprognostic (7.06e-2)" "unprognostic (2.92e-2)" "unprognostic (3.73e-3)" "unprognostic (5.98e-2)" "unprognostic (1.10e-1)" "unprognostic (1.39e-1)" "unprognostic (3.60e-1)" "unprognostic (1.07e-1)" "unprognostic (2.93e-1)" "unprognostic (9.31e-3)" "unprognostic (2.33e-1)" "unprognostic (1.87e-1)" "unprognostic (1.95e-1)" 9.0 7.7 4.7 11.1 5.1 25.5 9.1 7.0 6.2 7.6 4.4 12.8 10.6 9.0 9.0 11.6 7.2 6.0 8.9 4.8 4.3 9.0 9.5 12.2 13.4 6.7 5.2 6.9 15.5 5.7 7.7 21.0 5.9 10.6 13.7 9.9 13.6 6.2 10.1 15.8 12.4 7.8 5.1 12.8 10.9 12.7 5.0 14.0 10.0 7.2 14.6 8.5 9.4 6.9 16.0 12.2 37.3 25.9 12.5 10.0 59.1 14.8 13.0 14.6 15.5 39.0 24.3 37.1 11.7 14.5 19.7 26.9 40.5 26.6 23.8 56.6 33.1 54.7 13.4 27.1 28.5 57.7 32.4 13.3 31.4 23.2 52.3 9.0 24.2 41.9 27.6 21.8 15.7 27.8 35.2 30.6 55.8 31.4 13.0 36.6 39.6 23.3 14.6 24.6 21.0 24.2 10.4 26.8 21.7 28.9 28.8 32.9 22.2 8.4 13.5 16.7 18.9 20.2 22.6 39.7 13.6 31.5 16.8 4.6 1.9 0.4 2.8 1.6 3.1 2.0 2.8 3.0 2.2 1.4 2.4 2.6 0.5 4.2 2.5 2.5 1.7 2.7 4.7 5.1 7.0 6.2 4.8 4.3 6.7 5.2 5.9 5.1 5.0 6.9 9.5 3.2 15.3 13.7 11.7 7.0 5.2 4.6 8.0 11.7 8.4 7.6 6.2 5.7 5.6 0.0 8.4 19.3 19.4 12.7 1.9 7.3 16.8 9.0 9.4 10.0 11.4 6.3 16.8 13.5 18.5 6.4 11.2 12.1 12.0 12.5 8.6 6.0 10.4 16.8 12.7 16.3 0.0 16.3 8.0 5.6 6.5 9.9 5.4 12.2 9.9 4.5 13.4 14.1 27.3 15.0 19.2 4.9 16.9 11.2 6.5 3.6 6.0 9.5 0.0 7.8 7.2 14.0 11.6 10.5 7.2 26.8 11.5 5.2 14.8 8.1 PRR15L "ATAD4, MGC11242" ENSG00000167183 "Proline rich 15 like" Q9BU68 17 47951967-47957883 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 178.4;pancreas: 103.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 203.0;Distal tubular cells: 170.2;Intestinal goblet cells: 127.8;Paneth cells: 226.4;Proximal enterocytes: 263.7;Undifferentiated cells: 100.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "OE19: 205.6" "Not detected" "Not detected" HPA022918 Approved Approved Cytosol No NA "Cluster 15: NK-cells - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" Cytosol "HPA022918: AB_2060743" "unprognostic (9.91e-2)" "unprognostic (4.77e-2)" "unprognostic (8.18e-2)" "unprognostic (5.75e-3)" "unprognostic (1.83e-1)" "unprognostic (2.31e-2)" "unprognostic (2.48e-1)" "unprognostic (5.22e-2)" "unprognostic (2.86e-1)" "unprognostic (1.22e-1)" "unprognostic (1.06e-1)" "unprognostic (8.32e-2)" "prognostic favorable (6.29e-13)" "prognostic favorable (1.69e-5)" "unprognostic (1.36e-1)" "unprognostic (8.26e-2)" "unprognostic (3.34e-2)" 2.2 0.1 0.0 7.9 0.1 0.1 38.8 0.2 0.2 13.4 9.5 111.2 178.4 1.4 18.3 12.9 26.5 22.0 0.4 0.8 0.0 28.0 1.9 21.7 0.2 0.1 0.0 0.3 103.9 0.8 8.5 0.0 0.0 17.7 124.3 0.0 51.8 15.8 0.1 10.0 128.5 3.3 0.0 0.0 84.4 2.5 0.0 0.4 67.8 0.0 2.0 2.7 6.7 0.1 3.8 0.6 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 8.6 5.8 0.2 0.3 0.0 0.0 20.5 0.0 0.1 0.0 0.4 0.7 0.2 0.0 2.6 0.0 0.4 0.4 0.0 4.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 19.7 0.4 0.4 0.0 205.6 0.7 0.3 0.0 1.4 1.1 2.6 11.7 0.5 0.0 35.7 0.0 0.0 24.1 0.0 0.1 0.3 0.0 0.7 0.1 0.1 0.1 0.3 0.4 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 22.4 19.8 0.3 0.1 0.0 2.6 2.4 0.0 0.0 16.7 8.9 0.1 80.1 19.8 16.5 0.0 0.0 0.1 203.0 170.2 35.6 5.5 9.8 0.3 0.2 31.6 0.0 0.1 36.1 0.0 0.4 55.5 3.9 0.0 0.0 0.0 0.8 0.1 0.0 0.1 127.8 24.4 0.0 0.0 9.0 1.2 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 11.6 226.4 0.4 0.2 15.6 263.7 30.0 19.2 0.0 0.0 0.0 1.0 11.1 0.1 7.3 0.0 0.0 0.6 0.0 100.9 9.9 PRR4 "LPRP, PROL4" ENSG00000111215 "Proline rich 4" Q16378 12 10845849-10849475 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 45 "salivary gland: 6616.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 92.8;Cone photoreceptor cells: 139.7;Horizontal cells: 85.8;Rod photoreceptor cells: 119.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 3.8" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 4 "OE19: 2.8" HPA042133 Supported "Secreted to digestive system" NA NA 14000000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA042133: AB_10793979" "unprognostic (1.34e-1)" "unprognostic (2.13e-1)" "unprognostic (1.35e-2)" "unprognostic (1.74e-2)" "unprognostic (1.99e-1)" "unprognostic (5.03e-2)" "unprognostic (3.01e-3)" "unprognostic (3.91e-2)" "unprognostic (1.70e-1)" "unprognostic (1.23e-1)" "unprognostic (3.19e-2)" "unprognostic (1.09e-2)" "unprognostic (3.57e-6)" "unprognostic (2.81e-2)" "unprognostic (9.15e-2)" "unprognostic (1.21e-1)" "unprognostic (2.15e-2)" 1.9 2.0 0.6 0.0 0.6 0.1 9.7 0.6 1.8 0.1 0.6 0.2 7.6 0.0 0.0 148.1 0.0 0.0 0.4 0.6 0.6 0.2 0.2 74.4 0.0 0.8 0.6 0.1 2.7 0.0 2.0 0.1 0.6 4.0 0.0 0.0 6616.8 0.1 0.8 73.4 0.2 0.0 0.6 0.1 66.0 0.5 0.6 0.0 0.1 0.0 0.5 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.3 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.6 0.1 2.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.6 1.8 0.6 0.6 0.8 0.6 0.6 0.6 0.6 0.6 0.3 3.2 0.0 0.0 22.0 3.1 6.8 19.9 9.6 92.8 7.5 2.8 1.8 7.2 8.2 1.8 139.7 16.4 20.1 6.3 1.9 0.1 10.2 0.1 0.2 9.6 16.2 14.1 0.0 0.4 2.5 9.3 10.7 0.1 8.9 0.4 14.6 5.9 7.7 85.8 0.0 6.4 24.4 8.7 6.0 13.9 21.8 6.1 28.4 0.0 7.9 18.2 56.7 0.0 0.0 3.4 14.4 24.5 17.1 9.3 7.9 0.2 6.8 119.2 13.1 23.0 7.1 13.5 5.7 8.1 2.3 4.0 20.1 0.5 9.6 4.0 PRRG1 PRGP1 ENSG00000130962 "Proline rich and Gla domain 1" O14668 X 37349309-37457292 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 39.4" "Cell type enriched" "Detected in many" 6 "Oligodendrocytes: 229.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 79.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078129 Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Vesicles, Plasma membrane" Nucleoplasm "HPA078129: AB_2686878" "unprognostic (8.82e-2)" "prognostic unfavorable (4.65e-4)" "unprognostic (8.34e-2)" "unprognostic (2.08e-3)" "unprognostic (1.92e-1)" "unprognostic (5.11e-3)" "unprognostic (2.24e-2)" "unprognostic (7.23e-3)" "unprognostic (1.01e-2)" "unprognostic (1.74e-2)" "prognostic unfavorable (1.22e-4)" "unprognostic (8.21e-2)" "prognostic favorable (2.05e-7)" "unprognostic (1.43e-2)" "unprognostic (1.81e-1)" "unprognostic (1.08e-2)" "unprognostic (1.48e-1)" 8.6 3.7 12.3 2.1 24.9 0.2 5.2 21.6 19.7 4.4 4.7 4.0 2.9 4.3 1.5 4.1 2.6 8.8 6.4 12.9 15.9 10.5 7.9 5.5 1.7 26.7 21.3 4.2 1.6 1.2 1.4 8.1 25.3 3.4 4.1 1.5 2.9 7.8 15.9 2.2 3.0 5.4 18.4 2.9 2.4 1.5 18.4 1.5 8.3 7.8 1.0 5.6 3.8 39.4 32.3 7.2 5.6 5.6 18.7 15.4 2.4 14.1 17.6 4.7 8.2 17.1 20.2 0.0 21.8 10.4 8.9 10.7 15.6 10.0 8.3 0.1 5.2 5.2 7.7 5.7 22.6 0.0 7.2 23.2 8.1 9.1 7.7 9.4 24.8 0.0 2.6 0.1 16.5 2.4 0.1 0.1 6.8 5.1 13.4 0.0 13.1 0.0 79.2 1.7 0.0 0.1 9.7 15.6 6.1 15.3 0.1 3.5 17.6 7.5 4.2 14.2 4.1 0.0 0.1 0.0 7.3 0.0 7.3 0.7 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 12.3 24.9 21.6 19.7 12.9 15.9 26.7 21.3 25.3 18.4 18.4 39.4 29.7 6.4 4.2 15.7 0.0 11.3 4.8 7.6 5.2 2.2 5.3 5.3 8.1 15.7 2.7 33.1 0.0 7.0 0.2 7.6 7.9 6.8 0.7 3.3 12.9 18.4 3.0 0.0 23.3 3.1 14.9 9.6 4.6 9.2 1.3 3.9 17.9 16.3 4.8 18.5 10.8 5.7 14.2 4.1 5.3 0.4 4.7 1.4 3.6 31.9 0.8 2.2 0.0 12.5 229.8 18.7 7.5 2.6 0.0 9.1 4.3 9.4 2.9 0.5 6.6 8.3 8.4 2.5 4.2 5.2 6.3 10.4 0.4 3.5 4.8 8.1 PSAT1 PSA ENSG00000135069 "Phosphoserine aminotransferase 1" Q9Y617 9 78297125-78330093 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Serine biosynthesis" "Aminotransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 175.0;liver: 267.9" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 115.5;Glandular and luminal cells: 145.9;Hepatocytes: 161.7;Proximal tubular cells: 304.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 15.1" "Lineage enriched" "Detected in many" 5 "T-cells: 15.1" "Cell line enhanced" "Detected in many" "hTCEpi: 1170.1;SK-MEL-30: 752.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB014882, CAB040567, HPA042924" Enhanced Enhanced Cytosol NA NA 2400000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 22: Non-specific - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "CAB014882: , CAB040567: , HPA042924: AB_2678223" "unprognostic (8.26e-3)" "unprognostic (4.69e-2)" "unprognostic (1.46e-1)" "prognostic unfavorable (5.62e-5)" "unprognostic (4.05e-3)" "unprognostic (1.41e-1)" "unprognostic (2.21e-3)" "unprognostic (1.86e-1)" "unprognostic (9.85e-2)" "unprognostic (2.25e-2)" "unprognostic (4.53e-2)" "unprognostic (1.07e-1)" "prognostic unfavorable (6.00e-7)" "unprognostic (3.87e-3)" "unprognostic (1.21e-1)" "unprognostic (8.07e-3)" "unprognostic (1.71e-1)" 7.8 65.8 123.3 7.3 124.6 2.0 5.1 130.5 175.0 5.1 92.8 5.9 5.4 4.3 61.6 33.2 34.7 1.7 2.7 122.4 126.5 136.7 267.9 5.1 9.3 130.2 122.4 5.6 129.1 9.7 7.6 3.0 129.9 10.0 5.5 6.2 19.2 4.0 0.6 57.2 4.5 3.3 133.6 6.0 19.4 10.4 120.3 30.0 30.3 0.5 12.4 7.3 11.2 161.6 222.8 146.0 121.1 215.6 35.1 41.2 284.7 184.3 130.4 91.8 170.6 38.2 41.9 143.2 79.8 416.9 82.9 215.3 209.1 203.6 136.4 141.2 73.9 49.2 60.8 293.3 322.0 277.6 84.6 131.1 1170.1 122.0 322.9 22.6 85.0 548.3 53.8 358.2 77.1 83.2 95.8 44.3 278.2 415.1 158.4 46.5 78.6 173.4 126.6 50.9 54.9 127.0 51.1 87.7 752.3 75.9 42.0 344.1 19.9 23.2 73.5 85.9 151.5 242.0 242.7 0.8 268.9 215.6 112.1 0.0 0.0 0.0 5.2 0.0 5.9 3.1 5.0 7.0 0.3 1.3 8.1 7.5 0.3 0.0 0.1 0.0 15.1 3.3 123.3 124.6 130.5 175.0 122.4 126.5 130.2 122.4 129.9 133.6 120.3 161.6 0.4 0.0 0.0 70.2 11.0 41.9 8.8 18.9 115.5 0.9 1.8 3.9 0.6 1.5 4.7 11.0 0.0 32.0 2.2 2.0 62.6 11.5 1.7 77.7 10.3 3.7 3.6 29.9 7.3 48.4 13.7 4.2 6.6 145.9 0.0 0.5 3.6 161.7 5.3 5.0 6.0 4.8 18.3 4.4 2.9 3.8 5.0 3.4 19.6 5.6 3.8 26.7 0.0 48.2 78.8 22.7 0.1 1.9 29.1 16.0 0.3 304.1 3.8 1.1 0.0 33.5 14.3 1.6 3.7 35.5 50.7 9.3 8.6 68.2 4.2 11.8 PSRC1 DDA3 ENSG00000134222 "Proline and serine rich coiled-coil 1" Q6PGN9 1 109279556-109283186 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 101.5;choroid plexus: 47.9;retina: 41.6" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 30.1;Oligodendrocytes: 95.2;Peritubular cells: 44.8;Rod photoreceptor cells: 71.0" "Cancer enriched" "Detected in all" 4 "glioma: 50.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 12.0" "Group enriched" "Detected in many" 11 "dendritic cells: 5.4;granulocytes: 7.1;monocytes: 12.0" "Low cell line specificity" "Detected in all" "Group enriched" "Detected in many" 5 "amygdala: 3.5;cerebral cortex: 7.7;hippocampal formation: 5.7;white matter: 3.4" "Low region specificity" "Detected in all" HPA056561 Supported Nucleoplasm,Cytosol NA Yes "Cluster 25: Monocytes - Inflammatory response" "Cluster 77: Retina - Visual perception" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 46: Photoreceptor cells - Phototransduction" Cytosol Nucleoplasm "HPA056561: AB_2683175" "unprognostic (1.14e-1)" "unprognostic (1.65e-1)" "unprognostic (1.42e-3)" "unprognostic (6.78e-3)" "unprognostic (2.17e-1)" "unprognostic (4.76e-2)" "prognostic unfavorable (1.36e-9)" "unprognostic (3.51e-2)" "unprognostic (6.21e-2)" "unprognostic (4.88e-3)" "unprognostic (1.76e-2)" "unprognostic (1.92e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (9.43e-2)" "unprognostic (2.08e-1)" "unprognostic (1.90e-1)" "unprognostic (2.12e-1)" 2.0 1.9 64.7 3.8 84.0 7.9 2.4 76.5 84.1 5.1 47.9 3.9 4.3 3.1 2.6 7.6 3.5 3.0 3.0 69.7 71.2 2.7 4.5 5.3 3.6 78.0 79.9 3.3 1.5 3.2 4.2 4.0 83.0 5.5 2.7 41.6 2.4 4.5 0.9 5.2 4.5 3.9 67.9 3.9 3.4 13.3 74.1 14.2 2.3 0.9 4.3 3.2 5.8 101.5 56.0 28.2 112.9 55.1 4.4 8.7 31.0 43.1 34.7 57.6 55.1 43.7 22.7 28.2 15.4 21.4 27.1 38.9 61.4 35.4 48.1 11.0 29.6 17.7 40.5 36.2 5.0 19.0 19.3 10.0 3.3 22.8 16.2 21.5 28.7 32.9 40.9 12.5 46.8 50.5 29.2 12.9 46.9 25.4 31.8 44.4 108.7 9.5 19.6 14.4 47.2 27.3 24.3 36.8 43.6 40.8 22.3 18.0 14.9 35.4 57.9 25.1 72.5 9.7 6.9 9.8 28.6 44.9 100.9 0.0 12.0 1.9 0.6 4.8 0.4 0.0 0.7 0.2 5.4 0.0 0.4 0.3 7.1 0.3 2.7 0.0 0.7 3.4 64.7 84.0 76.5 84.1 69.7 71.2 78.0 79.9 83.0 67.9 74.1 101.5 0.7 0.0 3.9 9.8 0.5 2.0 1.8 2.3 0.6 6.7 2.1 5.6 1.3 1.5 0.5 1.8 25.0 17.6 1.0 2.0 0.0 0.9 1.1 0.5 3.2 2.3 0.0 0.8 19.3 0.9 30.1 4.4 0.5 1.1 1.3 12.9 2.9 1.2 10.9 3.3 3.8 3.9 4.1 4.4 1.8 2.6 5.9 4.9 1.8 2.8 2.2 10.0 0.0 18.1 95.2 0.5 0.6 44.8 0.6 1.0 0.6 2.9 0.9 71.0 0.0 5.5 4.7 5.0 1.5 6.5 1.1 2.9 1.5 1.1 5.4 1.3 PTGS1 "COX1, PGHS-1, PTGHS" ENSG00000095303 "Prostaglandin-endoperoxide synthase 1" P23219 9 122370530-122395703 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Dioxygenase, Oxidoreductase, Peroxidase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 108.3;skin 1: 152.5;urinary bladder: 175.0" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 109.9;Glandular and luminal cells: 191.9;granulocytes: 208.0;Hepatic stellate cells: 61.8;Macrophages: 55.3;Suprabasal keratinocytes: 58.7" "Cancer enhanced" "Detected in all" "ovarian cancer: 53.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 28.9" "Group enriched" "Detected in many" 6 "dendritic cells: 20.0;granulocytes: 28.9;monocytes: 13.1" "Cell line enhanced" "Detected in many" "ASC diff: 113.7;ASC TERT1: 89.5;BJ: 115.2;BJ hTERT+: 156.0;HEL: 73.6;HMC-1: 298.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA002834, CAB020315" Enhanced Supported "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 2100000 "Cluster 2: Granulocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 3: HMC-1 - Innate immune response" "Cluster 44: Endometrium - Transcription" "Golgi apparatus" Vesicles "CAB020315: , HPA002834: AB_1079711" "unprognostic (4.20e-1)" "unprognostic (6.23e-2)" "unprognostic (1.08e-2)" "unprognostic (2.27e-2)" "unprognostic (5.88e-2)" "unprognostic (2.00e-2)" "unprognostic (1.22e-3)" "unprognostic (3.32e-1)" "unprognostic (2.24e-1)" "unprognostic (3.16e-2)" "unprognostic (1.23e-1)" "unprognostic (1.46e-1)" "prognostic unfavorable (8.68e-4)" "unprognostic (4.03e-2)" "unprognostic (1.78e-2)" "unprognostic (2.08e-1)" "prognostic unfavorable (9.35e-4)" 12.8 2.9 3.1 10.5 3.2 9.0 6.7 4.2 4.8 5.8 5.5 108.3 10.8 6.1 2.2 67.3 43.2 9.6 12.6 7.4 5.5 9.3 3.0 11.3 4.6 6.5 5.2 2.0 1.8 2.0 4.8 2.2 6.3 21.1 24.2 0.7 4.3 6.1 2.1 152.5 17.7 16.1 6.7 8.0 20.5 0.9 7.0 2.2 3.2 4.0 11.6 175.0 15.9 11.9 0.3 0.5 0.4 0.0 113.7 89.5 0.0 115.2 156.0 1.0 1.1 0.0 0.2 4.2 5.4 19.7 0.3 7.1 0.4 10.5 0.9 0.0 0.2 73.6 0.6 0.0 32.9 5.2 298.4 46.1 1.2 5.7 0.3 0.0 42.3 0.1 0.1 0.3 2.3 0.0 0.2 6.6 1.6 0.0 0.5 0.3 1.4 8.6 14.7 0.0 0.5 0.6 0.6 9.5 0.2 0.5 0.3 8.4 1.0 0.7 0.6 1.7 0.1 0.3 0.2 0.0 0.4 31.6 0.3 28.9 12.1 23.3 0.0 13.1 0.0 2.4 0.0 0.0 20.0 3.5 0.1 0.0 5.2 2.8 10.2 1.4 0.2 21.9 3.1 3.2 4.2 4.8 7.4 5.5 6.5 5.2 6.3 6.7 7.0 11.9 0.9 0.0 6.6 0.0 5.9 9.9 2.6 7.7 0.0 0.1 1.1 1.4 1.6 4.3 2.2 42.3 0.0 0.1 0.2 0.1 0.0 0.6 0.1 109.9 10.4 24.7 1.8 18.7 0.8 0.5 0.3 10.7 2.0 191.9 208.0 0.1 61.8 0.8 26.1 0.0 0.5 0.6 4.1 15.5 20.7 0.3 1.5 55.3 3.6 16.9 11.7 0.0 7.2 1.0 0.1 0.6 0.6 0.0 0.3 2.8 0.0 0.0 0.8 0.1 0.0 1.4 3.6 0.0 0.2 18.2 58.7 0.4 3.4 0.1 1.0 0.8 PTH2R PTHR2 ENSG00000144407 "Parathyroid hormone 2 receptor" P49190 2 208359714-208854503 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "retina: 16.5" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 12.5;Distal tubular cells: 7.9;Excitatory neurons: 15.9;Proximal tubular cells: 16.1;Rod photoreceptor cells: 26.5" "Cancer enhanced" "Detected in many" "renal cancer: 6.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "EFO-21: 10.7;HEL: 16.0;HL-60: 4.0;SH-SY5Y: 6.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA010655 Approved NA NA "Cluster 77: Retina - Visual perception" "Cluster 36: HEL - Hemostasis" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA010655: AB_2668333" "unprognostic (4.76e-3)" "unprognostic (1.39e-3)" "unprognostic (1.64e-1)" "unprognostic (5.78e-2)" "unprognostic (3.77e-1)" "unprognostic (8.28e-2)" "unprognostic (1.23e-1)" "unprognostic (1.11e-1)" "unprognostic (2.87e-1)" "unprognostic (3.45e-2)" "unprognostic (2.14e-2)" "unprognostic (1.70e-1)" "unprognostic (1.09e-3)" "unprognostic (2.54e-3)" "unprognostic (6.87e-2)" "unprognostic (1.30e-2)" "unprognostic (1.37e-2)" 1.2 0.3 2.2 0.1 1.1 4.2 0.9 0.0 3.1 0.0 0.1 0.0 0.0 0.7 2.1 0.0 0.0 0.0 0.0 2.4 2.0 0.2 0.6 0.1 0.1 0.3 0.6 0.0 0.6 0.0 0.3 1.2 0.2 0.5 0.0 16.5 3.6 0.5 0.0 0.1 0.0 0.5 0.1 0.1 0.0 0.5 4.5 0.0 0.0 0.0 0.1 0.0 0.0 1.5 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 10.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 2.2 1.1 0.0 3.1 2.4 2.0 0.3 0.6 0.2 0.1 4.5 1.5 0.1 0.0 0.0 0.3 0.6 0.0 0.0 0.1 0.0 1.1 1.8 3.2 0.2 0.0 0.1 5.5 12.5 0.5 0.9 0.0 7.9 0.1 0.6 0.2 0.5 0.1 1.8 4.2 15.9 0.0 0.1 0.8 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 4.1 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 1.0 0.1 2.5 2.1 2.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 16.1 0.0 26.5 0.0 0.0 0.4 0.6 0.4 0.0 0.0 0.1 0.1 0.3 0.0 0.0 PTK2 "FADK, FAK, FAK1, PPP1R71" ENSG00000169398 "Protein tyrosine kinase 2" Q05397 8 140657900-141002216 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Angiogenesis "Developmental protein, Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 295.2;Excitatory neurons: 584.9;Oligodendrocyte precursor cells: 353.9;Oligodendrocytes: 791.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001842, CAB004036, HPA029671" Approved Supported "Vesicles,Focal adhesion sites,Cytosol" NA Yes 25000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Focal adhesion sites" "Vesicles, Cytosol" "CAB004036: AB_2269034, HPA001842: AB_1855891, HPA029671: AB_10610288" "prognostic unfavorable (3.21e-4)" "unprognostic (3.86e-2)" "unprognostic (1.95e-1)" "prognostic unfavorable (9.11e-4)" "unprognostic (1.93e-1)" "unprognostic (2.28e-1)" "unprognostic (3.02e-2)" "unprognostic (1.27e-1)" "unprognostic (1.97e-1)" "unprognostic (2.96e-2)" "unprognostic (1.06e-2)" "unprognostic (2.38e-1)" "unprognostic (2.80e-2)" "unprognostic (2.94e-2)" "unprognostic (1.11e-1)" "unprognostic (1.53e-1)" "unprognostic (2.90e-2)" 51.0 40.4 83.8 19.5 115.1 6.7 42.1 62.4 99.9 40.3 51.0 37.2 25.8 37.3 49.7 25.6 34.0 32.1 36.9 84.5 77.3 42.6 30.1 39.4 25.3 79.1 87.6 33.7 32.1 53.1 21.3 74.2 81.0 34.0 35.3 35.5 39.9 41.6 38.7 29.6 29.5 37.6 67.6 22.8 32.8 38.9 86.7 11.9 38.7 39.4 25.8 43.9 34.0 154.5 52.6 81.9 111.0 40.3 45.8 48.8 71.6 50.8 70.0 46.3 45.3 35.9 42.1 31.7 111.7 65.3 65.0 60.3 66.1 116.0 69.6 0.3 30.8 70.1 44.3 50.0 62.5 0.1 31.8 33.4 55.8 58.0 81.0 121.5 139.0 44.0 72.0 0.8 62.9 91.0 0.9 0.7 43.2 113.2 90.3 46.8 60.9 1.5 97.7 117.3 43.9 54.8 79.0 25.0 52.0 97.2 59.2 1.2 84.9 45.2 85.5 54.0 58.1 0.0 0.6 3.4 58.7 0.6 62.9 1.6 3.3 0.0 0.2 1.4 0.0 5.3 0.6 0.0 4.5 6.3 4.4 1.6 1.3 4.7 0.8 6.1 0.2 3.9 83.8 115.1 62.4 99.9 84.5 77.3 79.1 87.6 81.0 67.6 86.7 154.5 71.3 32.1 33.1 295.2 20.6 33.3 70.1 36.3 64.9 55.2 29.3 23.5 29.6 32.9 32.1 55.2 60.5 37.0 8.0 23.1 23.5 27.2 68.4 29.3 43.3 54.3 25.8 8.4 584.9 23.3 53.7 37.2 37.8 46.5 9.5 84.7 37.5 15.7 8.1 67.3 263.6 23.0 30.5 15.2 15.9 38.8 23.9 19.4 24.9 159.3 3.9 40.9 0.0 353.9 791.4 43.1 23.5 21.8 1.7 82.4 29.3 25.6 33.7 55.0 98.6 32.7 128.4 88.9 65.5 42.8 25.9 33.2 3.4 67.0 24.1 87.3 PTK6 BRK ENSG00000101213 "Protein tyrosine kinase 6" Q13882 20 63528001-63537376 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 109.4;skin 1: 53.9;vagina: 43.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 132.1;Gastric mucus-secreting cells: 59.1;Intestinal goblet cells: 42.5;Paneth cells: 97.6;Proximal enterocytes: 80.2;Squamous epithelial cells: 48.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "A-431: 22.1;CAPAN-2: 41.4;HaCaT: 33.9;hTCEpi: 45.0;OE19: 57.0;RT4: 26.4;T-47d: 25.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB032952, HPA036070, HPA036071" Approved Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Nuclear bodies, Plasma membrane, Cytosol" "CAB032952: AB_634461, HPA036070: AB_10602292, HPA036071: AB_10669982" "unprognostic (2.32e-2)" "unprognostic (1.36e-1)" "unprognostic (1.05e-1)" "unprognostic (2.42e-2)" "unprognostic (1.41e-1)" "unprognostic (1.35e-1)" "unprognostic (1.04e-1)" "unprognostic (2.29e-1)" "unprognostic (3.03e-1)" "unprognostic (3.72e-2)" "prognostic unfavorable (1.96e-4)" "unprognostic (1.28e-1)" "prognostic unfavorable (1.26e-9)" "unprognostic (4.19e-2)" "unprognostic (1.74e-1)" "unprognostic (1.73e-1)" "unprognostic (4.24e-2)" 0.5 0.1 0.6 3.6 1.7 0.8 3.8 2.9 1.7 19.8 0.0 26.5 28.9 0.4 0.1 109.4 0.4 3.5 0.2 0.6 0.9 0.8 5.2 2.6 0.6 1.6 1.0 0.3 3.6 0.0 0.2 0.3 1.7 3.1 15.7 0.8 19.1 0.6 0.6 53.9 22.2 0.8 0.6 0.8 26.2 0.3 1.1 0.3 0.2 0.0 6.4 9.8 43.2 5.4 22.1 2.6 0.3 0.3 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.5 41.4 0.1 7.2 0.0 0.1 33.9 0.0 0.1 0.0 5.4 0.4 0.0 10.2 0.1 0.1 0.0 6.7 0.0 45.0 0.0 0.2 0.2 0.0 0.1 0.2 2.5 0.2 12.5 0.0 0.2 0.2 57.0 15.5 0.1 1.2 0.5 0.0 26.4 0.3 2.2 2.6 8.1 0.0 0.1 25.2 1.6 0.2 0.3 0.4 0.8 0.3 0.5 0.1 0.1 0.4 0.5 1.1 0.4 0.7 0.1 0.1 0.5 0.5 0.3 0.1 0.0 1.3 0.3 0.1 0.1 0.3 0.0 0.4 0.1 0.1 0.3 0.6 1.7 2.9 1.7 0.6 0.9 1.6 1.0 1.7 0.6 1.1 5.4 0.3 12.8 25.6 0.3 1.4 5.9 2.6 7.7 5.2 2.2 7.0 4.3 0.4 12.8 14.9 0.0 2.1 0.2 0.2 132.1 0.0 1.4 0.2 0.4 0.5 3.2 5.4 0.0 0.1 1.6 0.2 1.4 59.1 1.3 9.5 0.2 0.4 1.7 0.6 0.0 0.1 42.5 2.0 2.2 2.0 0.0 0.3 2.6 0.0 0.0 1.0 1.6 1.0 0.0 0.8 17.6 97.6 0.0 0.1 1.5 80.2 0.2 8.9 3.7 0.0 2.3 1.1 0.2 0.3 48.0 15.5 0.1 2.0 0.2 32.1 15.9 PTPN13 "PTP-BAS, PTP-BL, PTP1E, PTPL1" ENSG00000163629 "Protein tyrosine phosphatase non-receptor type 13" Q12923 4 86594315-86815171 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 124.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 223.1;Astrocytes: 165.2;Oligodendrocytes: 200.2;Rod photoreceptor cells: 179.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AF22: 117.6;RT4: 57.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002213, HPA063119" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 12: NES - Nervous system development" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm "Nucleoli fibrillar center, Cytosol" "CAB002213: AB_564089, HPA063119: " "unprognostic (5.36e-2)" "unprognostic (4.46e-1)" "unprognostic (1.11e-1)" "unprognostic (2.54e-3)" "unprognostic (4.02e-1)" "unprognostic (9.03e-3)" "unprognostic (4.43e-2)" "unprognostic (4.38e-2)" "unprognostic (2.46e-1)" "unprognostic (7.05e-2)" "unprognostic (3.69e-2)" "unprognostic (1.46e-1)" "unprognostic (1.28e-3)" "unprognostic (3.95e-3)" "unprognostic (2.26e-1)" "unprognostic (2.66e-1)" "unprognostic (2.85e-2)" 14.0 6.7 9.9 3.0 16.6 0.3 11.7 8.1 10.8 18.8 22.4 5.2 0.8 13.1 25.5 22.2 13.0 7.7 6.1 14.2 10.6 26.6 1.4 22.9 5.2 16.7 13.1 28.7 4.9 17.5 16.8 3.3 10.5 11.0 2.4 124.3 6.6 10.6 1.0 55.9 2.6 7.9 8.2 4.0 4.1 15.8 13.8 7.6 20.8 5.0 11.5 20.7 22.7 20.4 13.8 6.8 117.6 11.5 48.2 41.9 0.0 25.0 51.0 9.4 11.7 0.1 6.8 0.0 5.3 28.0 3.3 44.4 20.6 37.9 18.0 0.3 15.1 11.4 14.6 0.0 5.9 20.5 0.1 27.2 11.8 6.8 22.4 19.7 0.0 0.0 0.0 19.2 0.0 6.2 1.8 7.4 26.5 0.0 5.1 4.1 0.0 0.0 35.6 57.2 6.8 9.8 7.4 16.4 13.3 18.8 9.6 0.7 0.0 9.1 6.9 0.2 3.3 19.8 0.0 0.0 9.5 0.0 4.0 0.0 0.1 0.0 0.1 1.3 0.9 0.0 0.8 0.1 0.2 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 9.9 16.6 8.1 10.8 14.2 10.6 16.7 13.1 10.5 8.2 13.8 20.4 5.3 48.1 223.1 165.2 0.6 109.4 25.6 26.3 79.1 11.6 11.2 8.9 1.8 11.5 52.0 47.8 91.8 0.2 0.3 0.1 3.9 5.0 23.2 16.9 49.4 3.7 4.8 0.8 67.0 3.7 0.1 28.8 4.1 7.7 5.1 7.5 3.6 0.1 0.3 1.7 39.3 1.1 8.2 1.4 10.6 20.8 45.7 4.5 19.6 51.5 0.5 20.3 0.0 75.4 200.2 6.2 2.7 32.7 3.0 16.0 0.1 10.9 27.3 179.0 13.1 10.1 20.8 25.4 20.5 97.8 99.4 0.3 6.6 14.0 0.7 52.5 PTPN3 PTPH1 ENSG00000070159 "Protein tyrosine phosphatase non-receptor type 3" P26045 9 109375466-109498313 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 63.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 48.6" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "thalamus: 26.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "OE19: 29.4;RPTEC TERT1: 34.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038343, HPA046728" Approved NA NA "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" "HPA038343: AB_10671741, HPA046728: AB_2679776" "prognostic unfavorable (6.71e-4)" "unprognostic (3.48e-1)" "unprognostic (3.64e-2)" "prognostic favorable (1.52e-4)" "unprognostic (2.32e-2)" "unprognostic (1.27e-1)" "unprognostic (2.34e-1)" "unprognostic (4.86e-2)" "unprognostic (3.71e-2)" "unprognostic (5.38e-2)" "unprognostic (6.37e-2)" "unprognostic (3.57e-2)" "prognostic favorable (1.22e-15)" "unprognostic (1.64e-2)" "unprognostic (2.64e-1)" "unprognostic (1.11e-1)" "unprognostic (8.21e-2)" 4.0 2.2 7.1 1.7 1.0 0.1 7.5 0.0 2.6 6.6 8.5 9.5 12.4 2.2 17.7 13.2 10.1 2.7 21.1 3.2 5.2 23.0 29.5 5.7 1.1 0.3 14.7 0.6 14.8 10.7 2.9 7.3 1.6 5.9 10.1 2.5 8.5 5.1 63.5 30.1 12.9 1.4 0.4 0.3 9.7 3.2 26.7 3.6 10.1 46.9 4.4 4.2 7.2 0.4 11.1 13.5 0.5 3.5 0.0 0.0 21.1 2.3 0.0 2.9 3.2 7.2 17.7 0.0 2.4 0.1 7.3 25.8 3.7 15.2 2.9 6.2 8.2 0.0 6.2 7.5 0.1 0.0 0.1 0.2 16.0 3.6 7.7 1.2 0.0 4.5 0.0 0.1 0.2 14.0 19.3 3.3 1.6 29.4 10.0 0.1 4.4 0.3 34.0 21.1 8.6 1.8 5.9 21.8 0.0 7.1 12.5 1.8 0.1 1.0 8.2 1.4 0.0 10.4 18.2 0.0 11.2 0.0 7.7 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 7.1 1.0 0.0 2.6 3.2 5.2 0.3 14.7 1.6 0.4 26.7 0.4 0.4 16.0 28.4 0.7 0.5 11.9 25.9 19.3 4.0 13.4 7.8 8.6 48.6 24.3 24.7 31.3 0.0 23.6 0.1 30.0 17.6 14.5 21.5 27.6 3.1 3.3 13.1 0.0 16.1 19.2 23.7 1.8 15.8 38.4 1.3 0.9 4.6 36.3 2.6 0.0 5.2 18.7 8.2 0.0 1.8 18.5 1.2 0.8 3.6 1.0 0.7 0.3 1.0 0.5 0.6 29.1 24.0 1.9 0.2 26.1 27.9 19.2 28.4 2.2 6.6 3.2 6.0 1.6 10.4 7.0 20.6 10.8 0.8 0.4 18.4 29.0 PTTG1 "EAP1, HPTTG, PTTG, securin, TUTR1" ENSG00000164611 "PTTG1 regulator of sister chromatid separation, securin" O95997 5 160421855-160428739 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, DNA damage, DNA repair, Mitosis" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 160.1;lymphoid tissue: 144.9;testis: 175.6" "Cell type enhanced" "Detected in many" "Early spermatids: 770.5;Erythroid cells: 415.9;Langerhans cells: 412.3;Spermatocytes: 708.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "T-reg: 218.0" "Lineage enriched" "Detected in all" 7 "T-cells: 218.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008373, HPA008890, HPA045034" Enhanced Supported Nucleoli,Cytosol NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol Nucleoli "CAB008373: AB_592493, HPA008890: AB_1079717, HPA045034: AB_2679192" "unprognostic (6.48e-2)" "unprognostic (1.03e-2)" "unprognostic (1.40e-3)" "unprognostic (4.46e-3)" "unprognostic (5.81e-2)" "unprognostic (1.29e-1)" "prognostic unfavorable (1.62e-6)" "unprognostic (7.50e-3)" "unprognostic (5.24e-2)" "unprognostic (3.47e-2)" "unprognostic (2.13e-3)" "unprognostic (6.70e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (7.17e-2)" "unprognostic (1.72e-1)" "unprognostic (4.23e-2)" "unprognostic (3.35e-2)" 3.7 3.5 4.2 25.2 5.3 160.1 10.9 4.1 11.5 9.6 4.0 33.9 24.6 4.8 9.6 59.7 5.0 6.1 3.5 8.1 6.6 3.0 5.3 8.7 81.5 3.9 4.8 1.8 1.5 2.3 4.3 21.2 4.2 3.1 44.1 2.4 10.3 2.7 2.5 36.0 24.1 19.2 4.0 18.6 11.8 175.6 5.3 127.0 79.3 1.3 144.9 12.5 19.9 4.7 345.4 178.2 385.8 279.5 64.4 63.3 120.8 177.5 406.1 463.4 503.5 341.1 294.9 373.3 154.7 204.2 527.5 176.1 243.5 496.1 661.2 428.3 220.3 196.7 241.8 208.6 13.0 181.5 165.6 29.6 81.5 315.4 189.5 139.9 333.4 243.3 160.7 282.3 485.4 162.3 220.7 446.1 197.5 279.3 251.4 199.4 452.4 320.7 239.6 82.6 241.0 151.3 258.6 156.3 535.6 309.3 319.9 195.7 144.8 208.3 275.9 164.9 531.3 239.2 235.6 432.3 225.9 310.4 379.6 9.7 3.2 10.3 25.5 8.7 9.6 30.9 52.3 60.6 23.9 23.5 12.7 31.4 3.0 14.6 5.8 22.6 218.0 19.8 4.2 5.3 4.1 11.5 8.1 6.6 3.9 4.8 4.2 4.0 5.3 4.7 11.8 6.4 21.5 0.0 40.0 247.9 64.5 163.6 142.3 3.4 15.8 40.5 4.0 4.3 31.1 5.5 0.0 125.4 38.3 17.7 3.9 5.8 770.5 22.7 9.3 20.6 6.0 415.9 1.3 5.3 196.2 35.6 28.1 16.7 37.5 66.2 18.5 7.1 87.5 0.0 1.6 39.2 126.1 36.3 412.3 105.1 11.1 39.1 87.2 0.0 24.7 3.5 6.2 0.0 0.6 3.0 10.7 7.9 91.4 54.1 9.0 2.0 17.1 1.0 6.6 18.6 43.2 708.0 57.3 232.0 156.1 31.9 73.7 16.8 70.3 50.3 PYCARD "ASC, CARD5, TMS-1" ENSG00000103490 "PYD and CARD domain containing" Q9ULZ3 16 31201486-31203450 "Predicted intracellular proteins" "Apoptosis, Immunity, Inflammatory response, Innate immunity" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 84.7;skin 1: 90.5" "Cell type enhanced" "Detected in many" "Hofbauer cells: 425.8;Kupffer cells: 555.8;Macrophages: 344.2;Paneth cells: 360.0;Proximal enterocytes: 504.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 585.7;classical monocyte: 1098.3;eosinophil: 948.1;intermediate monocyte: 1138.3;myeloid DC: 829.2;neutrophil: 1638.4;non-classical monocyte: 1152.8;plasmacytoid DC: 769.2" "Group enriched" "Detected in all" 6 "dendritic cells: 829.2;granulocytes: 1638.4;monocytes: 1152.8" "Cell line enhanced" "Detected in many" "MCF7: 148.9;NB-4: 237.0;THP-1: 186.9;U-937: 112.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006853, CAB015948, HPA049074, HPA054496" Enhanced Supported Nucleoplasm,Nucleoli,Cytosol NA NA 640000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 31: Skin - Epidermis development" "Cluster 24: NB-4 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm "Nucleoli, Cytosol" "CAB006853: , CAB015948: , HPA049074: AB_2680621, HPA054496: AB_2682506" "unprognostic (1.00e-3)" "unprognostic (2.62e-2)" "unprognostic (2.40e-1)" "unprognostic (4.67e-3)" "unprognostic (3.34e-1)" "unprognostic (1.87e-1)" "unprognostic (5.29e-2)" "unprognostic (2.88e-2)" "unprognostic (3.12e-1)" "unprognostic (2.33e-1)" "unprognostic (6.52e-3)" "unprognostic (3.88e-2)" "prognostic unfavorable (6.09e-7)" "unprognostic (4.45e-3)" "unprognostic (2.51e-1)" "unprognostic (3.61e-2)" "unprognostic (6.97e-2)" 25.6 11.4 4.1 32.9 4.0 43.4 20.4 4.6 8.6 22.1 5.0 48.1 63.9 10.7 0.0 56.1 17.4 4.9 9.7 3.7 5.2 10.9 10.4 32.8 19.1 7.8 5.1 14.9 11.3 1.7 7.7 6.1 6.7 19.9 9.5 0.1 24.6 8.7 3.4 90.5 48.5 5.8 7.6 84.7 22.1 2.3 6.7 9.5 9.1 1.2 12.7 19.8 33.1 11.3 23.9 54.8 0.5 0.2 9.2 18.9 0.6 12.6 22.6 8.8 6.5 0.1 31.7 10.6 0.1 17.6 0.0 69.7 2.9 57.4 0.3 73.0 0.0 9.3 7.9 18.3 25.6 86.9 65.7 24.7 30.3 4.0 1.2 0.2 18.4 0.1 42.9 17.5 2.9 148.9 0.2 237.0 15.7 13.2 0.1 75.5 0.0 35.2 1.3 22.3 0.7 0.2 10.4 0.0 12.4 0.3 15.5 186.9 11.8 0.4 0.7 9.9 0.3 0.6 0.1 0.2 6.4 112.1 0.1 585.7 1098.3 948.1 178.4 1138.3 112.2 213.7 146.5 183.3 829.2 210.7 102.1 139.6 1638.4 219.2 1152.8 769.2 206.4 814.2 4.1 4.0 4.6 8.6 3.7 5.2 7.8 5.1 6.7 7.6 6.7 11.3 35.7 22.4 28.9 0.0 58.5 74.1 66.3 237.0 100.7 0.2 92.2 131.7 2.5 41.5 84.3 25.8 0.0 62.5 158.8 184.5 5.9 90.5 0.8 18.6 16.8 39.2 58.9 42.9 0.1 56.5 11.3 39.3 50.4 7.3 110.9 60.2 48.9 3.3 425.8 0.0 0.1 144.6 75.3 555.8 280.2 2.9 47.2 344.2 97.8 13.1 277.8 0.0 132.8 0.0 0.1 60.4 360.0 22.6 54.1 22.6 504.8 3.6 88.2 0.7 26.3 10.5 28.5 0.3 1.4 83.9 163.7 17.8 70.8 119.9 287.1 70.6 RAB10 ENSG00000084733 "RAB10, member RAS oncogene family" P61026 2 26034084-26137454 "Enzymes, Predicted intracellular proteins" "Protein transport, Transport" Hydrolase Neurodegeneration "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Suprabasal keratinocytes: 488.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045611 Approved NA Yes 4300000 "Cluster 51: Monocytes - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 10: Non-specific - Unknown function" "HPA045611: AB_10961124" "unprognostic (7.73e-3)" "unprognostic (2.45e-2)" "unprognostic (8.21e-3)" "prognostic unfavorable (7.40e-4)" "unprognostic (8.22e-3)" "unprognostic (2.10e-1)" "prognostic unfavorable (1.99e-5)" "unprognostic (9.22e-3)" "unprognostic (6.14e-2)" "unprognostic (2.96e-2)" "prognostic unfavorable (7.37e-5)" "unprognostic (1.06e-2)" "unprognostic (8.69e-3)" "unprognostic (1.05e-1)" "unprognostic (2.39e-1)" "unprognostic (1.31e-1)" "unprognostic (2.99e-2)" 47.4 51.5 42.8 44.2 49.0 17.7 45.1 48.7 56.7 55.6 29.7 58.8 41.3 38.9 40.3 172.9 39.6 41.9 49.8 41.2 47.3 56.8 48.5 39.9 42.8 52.9 46.9 37.1 37.7 66.3 21.5 40.9 54.4 42.6 57.9 29.0 51.7 41.6 213.9 71.0 46.3 48.1 51.5 44.4 58.8 24.0 46.4 43.8 54.2 114.0 64.5 78.5 78.1 62.8 117.1 139.7 63.8 53.1 131.2 108.2 61.9 90.3 76.8 69.7 61.6 83.2 83.8 77.9 83.4 96.7 79.5 62.0 77.3 84.4 73.9 82.3 56.0 135.1 54.4 134.8 122.6 112.2 73.5 89.0 135.9 85.9 100.3 109.6 89.0 48.9 114.1 76.7 95.1 52.0 69.1 87.1 65.2 139.5 81.7 65.2 133.4 132.8 141.6 111.8 90.1 83.7 75.2 135.1 94.9 70.5 59.5 80.1 110.2 107.1 56.2 75.7 97.2 50.5 84.2 124.4 107.9 132.6 83.5 58.0 75.5 35.5 31.5 135.2 38.6 33.4 36.9 34.1 69.9 32.0 31.1 35.2 54.6 50.6 152.6 24.3 44.6 81.0 42.8 49.0 48.7 56.7 41.2 47.3 52.9 46.9 54.4 51.5 46.4 62.8 70.8 80.1 49.7 37.9 56.2 341.8 195.5 156.4 122.3 23.8 85.2 64.6 76.4 85.8 134.7 92.0 8.4 121.0 48.7 168.8 115.4 188.3 35.5 67.8 76.7 78.4 65.2 101.0 43.6 96.0 204.4 80.7 97.3 98.3 50.7 44.0 53.2 66.8 159.7 26.9 36.0 94.1 107.8 157.2 285.1 29.6 62.7 151.6 88.9 36.5 246.8 104.9 38.1 47.7 78.1 136.8 123.8 70.0 63.6 199.7 85.9 135.2 107.4 32.7 85.5 94.1 159.5 85.3 73.4 255.9 488.0 128.3 59.3 65.6 117.7 334.3 RAB11FIP4 "FLJ00131, KIAA1821, MGC11316, RAB11-FIP4" ENSG00000131242 "RAB11 family interacting protein 4" Q86YS3 17 31391675-31538211 "Predicted intracellular proteins" "Host-virus interaction, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 78.4;testis: 48.8" "Cell type enhanced" "Detected in many" "Early spermatids: 334.6;Horizontal cells: 212.0;Late spermatids: 1251.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 78.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 78.7" "Cell line enhanced" "Detected in many" "BEWO: 64.3;Daudi: 36.8;Hep G2: 40.6;HMC-1: 41.5;RT4: 37.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063203 Approved NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" "HPA063203: AB_2684962" "unprognostic (2.11e-1)" "unprognostic (1.48e-1)" "prognostic favorable (2.70e-4)" "unprognostic (6.03e-3)" "unprognostic (4.29e-2)" "unprognostic (4.15e-2)" "unprognostic (1.11e-1)" "unprognostic (1.35e-3)" "unprognostic (2.71e-1)" "unprognostic (3.20e-1)" "unprognostic (1.16e-1)" "unprognostic (1.49e-1)" "prognostic favorable (7.74e-8)" "prognostic favorable (1.22e-4)" "unprognostic (3.00e-1)" "unprognostic (2.00e-2)" "unprognostic (4.13e-3)" 0.9 1.1 68.9 8.1 72.0 15.0 4.1 48.9 71.4 2.7 22.0 9.3 12.9 1.2 11.2 6.7 7.5 3.2 2.7 66.2 47.6 6.8 2.9 5.7 11.8 55.3 66.0 2.4 17.6 6.1 3.5 10.5 51.7 2.5 7.3 7.7 7.4 3.8 0.5 8.1 14.7 0.9 54.3 7.4 13.4 48.8 70.7 4.6 4.6 0.4 10.7 5.1 2.1 78.4 12.4 1.4 1.3 3.2 0.5 0.0 64.3 0.2 0.0 0.8 0.8 20.7 1.9 36.8 4.6 0.2 13.3 10.3 12.2 5.9 0.5 7.5 11.0 0.0 0.5 40.6 0.3 2.7 41.5 0.3 5.9 0.8 2.6 0.4 0.0 10.9 2.7 0.9 0.0 9.8 2.7 0.7 10.5 22.9 0.4 1.0 0.1 7.1 2.3 37.8 19.1 13.9 2.8 17.4 14.6 8.7 25.7 1.2 0.0 0.7 6.3 0.1 0.6 6.6 5.6 3.4 0.2 3.7 2.5 5.5 8.4 78.7 13.9 11.9 8.7 5.8 7.2 10.3 5.4 8.6 7.6 9.1 40.5 6.4 15.8 1.1 9.6 8.7 68.9 72.0 48.9 71.4 66.2 47.6 55.3 66.0 51.7 54.3 70.7 78.4 0.6 6.4 8.3 15.7 12.1 3.1 11.4 5.7 1.8 9.6 9.1 5.2 7.3 15.7 9.6 11.0 10.4 73.1 19.8 32.6 13.7 17.5 334.6 39.0 3.9 1.5 14.9 2.7 68.6 28.2 10.9 2.3 17.3 48.8 12.0 7.3 1.1 4.4 6.0 212.0 71.0 16.0 12.2 1.9 5.7 1251.4 5.3 6.3 10.6 1.9 11.1 53.7 26.8 13.6 72.3 24.8 20.2 4.9 7.0 11.1 25.9 12.4 18.1 7.4 0.0 3.1 2.7 8.3 9.7 4.4 3.0 50.3 15.2 0.2 21.1 15.4 RAB19 RAB19B ENSG00000146955 "RAB19, member RAS oncogene family" A4D1S5 7 140404058-140427974 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 3.9" "Cell type enhanced" "Detected in single" "Enteroendocrine cells: 1.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "CAPAN-2: 3.8;HDLM-2: 5.4;MCF7: 3.3;RT4: 4.8;SK-BR-3: 4.6;T-47d: 4.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA051077 Uncertain NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 3: T-cells - Adaptive immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 58: T-cells - T-cell receptor" "HPA051077: AB_2681336" "unprognostic (3.40e-1)" "unprognostic (2.07e-2)" "unprognostic (2.26e-1)" "unprognostic (3.10e-2)" "unprognostic (1.54e-1)" "unprognostic (6.48e-2)" "unprognostic (1.65e-1)" "unprognostic (2.35e-2)" "unprognostic (3.17e-2)" "unprognostic (2.72e-2)" "unprognostic (7.91e-2)" "unprognostic (2.53e-1)" "prognostic favorable (2.36e-8)" "unprognostic (1.73e-3)" "unprognostic (6.42e-2)" "unprognostic (3.44e-1)" "unprognostic (6.09e-3)" 0.1 0.2 1.0 1.1 0.7 3.9 0.5 1.7 1.1 0.2 0.5 2.2 2.2 0.3 0.9 0.2 0.7 0.7 0.2 0.6 0.6 1.6 0.3 0.7 1.1 0.7 0.5 0.1 1.7 3.1 0.9 0.3 0.9 0.6 2.7 0.3 0.6 0.2 0.6 0.6 2.0 0.2 0.1 0.5 1.5 0.2 1.1 1.0 2.1 0.0 0.8 0.7 0.0 1.9 0.7 0.2 0.1 0.3 0.0 0.0 1.0 0.0 0.0 0.0 0.0 1.3 3.8 0.2 0.4 0.0 0.1 0.8 0.0 0.6 0.0 5.4 0.3 0.1 0.6 0.2 0.0 0.2 0.4 0.0 0.1 0.0 0.1 0.0 0.0 0.4 0.2 0.4 0.0 3.3 0.5 0.3 0.1 0.4 0.3 0.1 0.1 0.1 1.8 4.8 0.8 0.1 0.1 4.6 0.0 0.3 4.8 0.1 0.1 0.2 0.1 0.2 0.1 0.2 0.1 0.2 0.1 0.2 0.1 0.8 0.3 0.4 0.9 0.2 1.6 0.5 1.0 1.5 0.1 0.6 1.1 1.3 1.3 0.9 0.2 0.4 2.1 0.3 1.0 0.7 1.7 1.1 0.6 0.6 0.7 0.5 0.9 0.1 1.1 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.6 0.0 0.0 1.8 0.0 0.7 0.0 0.0 0.0 0.5 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 RAB40C "RARL, RASL8C" ENSG00000197562 "RAB40C, member RAS oncogene family" Q96S21 16 589357-629272 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 58.0" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 56.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 14.0" "Lineage enriched" "Detected in many" 5 "granulocytes: 14.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076172 Approved Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 50: Non-specific - Ribosome" "Cluster 43: THP-1 - Innate immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA076172: " "unprognostic (8.04e-2)" "unprognostic (3.63e-1)" "unprognostic (2.00e-1)" "unprognostic (1.52e-1)" "unprognostic (5.38e-3)" "unprognostic (1.07e-2)" "prognostic unfavorable (1.18e-4)" "unprognostic (1.23e-1)" "unprognostic (4.61e-2)" "unprognostic (5.78e-2)" "unprognostic (3.45e-2)" "unprognostic (2.90e-1)" "unprognostic (1.37e-3)" "unprognostic (3.89e-2)" "unprognostic (6.20e-2)" "unprognostic (7.48e-2)" "unprognostic (4.00e-3)" 10.5 8.0 7.4 4.5 10.0 5.8 11.6 7.1 17.7 13.2 0.0 20.3 13.3 13.0 5.1 20.4 12.2 4.5 12.5 10.9 2.0 13.9 12.8 13.3 4.1 3.4 2.6 12.1 38.5 5.1 21.4 6.6 3.2 17.5 4.4 1.9 14.3 5.9 18.8 58.0 13.6 4.4 1.5 7.9 19.3 13.8 4.0 10.2 10.6 6.2 2.6 18.3 16.1 8.8 7.7 16.3 9.4 13.2 5.3 6.6 12.6 10.1 4.7 8.0 6.5 14.7 13.7 8.8 10.5 6.0 7.1 17.1 5.8 8.3 1.6 9.3 9.8 4.9 11.3 10.5 9.4 9.9 8.9 5.6 17.9 6.4 6.7 5.6 6.6 10.3 11.2 8.8 3.5 22.7 9.6 18.0 10.9 13.5 9.4 15.4 6.7 14.1 4.7 10.9 12.8 10.3 11.1 24.1 9.4 4.3 17.8 19.6 8.2 8.4 11.8 11.3 6.1 8.4 8.6 11.0 5.5 13.4 8.9 1.1 2.8 14.0 0.4 1.8 1.9 1.1 1.4 1.5 1.6 0.7 1.0 0.7 4.8 0.8 0.8 0.7 0.6 1.3 7.4 10.0 7.1 17.7 10.9 2.0 3.4 2.6 3.2 1.5 4.0 8.8 7.1 9.6 15.7 20.5 4.3 17.5 9.9 11.3 18.2 11.4 9.8 7.9 6.3 8.6 10.4 11.0 8.4 26.6 7.7 33.2 7.9 6.2 4.0 12.1 7.1 5.4 10.8 5.2 44.5 12.5 15.3 4.7 23.4 12.7 7.0 11.2 7.5 16.2 9.4 16.8 18.6 16.5 24.4 6.1 4.1 6.6 5.0 4.5 7.2 10.3 7.5 8.4 7.2 10.6 14.8 10.4 21.3 6.4 2.5 10.8 38.2 9.7 11.2 3.3 0.0 5.6 5.8 17.1 13.9 24.8 31.1 56.8 4.6 7.2 18.7 8.6 RAB5B ENSG00000111540 "RAB5B, member RAS oncogene family" P61020 12 55973913-55996683 "Predicted intracellular proteins, RAS pathway related proteins" "Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010224, HPA068337" Approved Supported Vesicles NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" Vesicles "CAB010224: AB_2175453, HPA068337: AB_2685974" "prognostic unfavorable (2.24e-5)" "unprognostic (1.86e-1)" "unprognostic (1.91e-1)" "unprognostic (7.66e-3)" "unprognostic (2.09e-1)" "unprognostic (8.42e-2)" "unprognostic (9.16e-3)" "unprognostic (3.09e-1)" "unprognostic (3.13e-1)" "unprognostic (8.31e-3)" "unprognostic (8.64e-2)" "unprognostic (2.26e-1)" "unprognostic (2.27e-2)" "unprognostic (2.46e-2)" "unprognostic (2.74e-1)" "unprognostic (2.85e-1)" "unprognostic (2.49e-1)" 50.9 54.4 95.4 39.4 102.3 35.0 68.2 106.2 96.8 76.8 76.5 72.2 52.4 73.8 92.4 99.8 75.7 55.8 87.2 93.1 99.5 70.1 68.8 72.9 44.5 103.5 105.6 85.4 47.9 112.1 31.4 63.4 106.0 74.6 80.6 72.9 61.7 94.6 100.6 92.4 50.4 79.9 103.6 48.1 67.0 57.1 99.9 64.0 64.6 127.6 76.0 65.6 69.6 112.9 62.3 39.1 80.2 59.4 128.5 115.9 72.1 56.1 102.3 68.3 57.5 67.5 76.7 34.7 65.5 107.6 50.3 44.8 51.4 77.8 63.3 44.1 39.5 39.3 53.1 38.6 94.5 33.2 61.6 94.9 142.7 64.2 54.2 153.0 87.0 42.2 36.2 99.3 87.3 42.3 42.6 51.9 35.8 51.5 35.2 36.5 49.9 45.1 128.2 100.7 40.0 35.6 73.1 72.4 89.0 88.3 104.6 102.5 72.3 44.5 32.5 32.8 22.2 56.4 46.9 21.8 71.5 30.7 38.4 18.5 10.1 32.6 11.1 9.3 10.3 8.9 9.0 9.9 8.0 6.9 10.2 8.0 27.4 7.6 10.6 8.0 7.6 8.9 95.4 102.3 106.2 96.8 93.1 99.5 103.5 105.6 106.0 103.6 99.9 112.9 24.4 57.7 37.1 13.1 26.7 51.7 26.5 34.0 35.3 33.3 54.4 38.2 53.2 55.8 34.0 42.3 52.1 44.0 29.1 88.1 35.2 49.4 11.1 24.1 22.8 30.8 38.9 29.8 21.4 37.1 42.8 33.1 37.2 33.9 19.7 34.1 42.1 86.0 31.1 16.8 23.4 51.1 16.2 46.4 52.3 27.7 53.4 25.4 35.6 11.2 64.7 41.6 32.0 11.1 26.3 71.3 44.4 59.5 27.1 57.0 44.7 35.9 23.9 31.6 59.2 31.9 33.2 36.8 25.6 64.7 89.2 88.0 25.0 23.4 42.7 65.8 RAB8A "MEL, RAB8" ENSG00000167461 "RAB8A, member RAS oncogene family" P61006 19 16111889-16134234 "Predicted intracellular proteins" "Autophagy, Cilium biogenesis/degradation, Protein transport, Transport" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041945 Approved "Nucleoplasm,Plasma membrane" No No 4800000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 9: Intestine - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 51: Myeloid cells - Hemostasis" "Nucleoplasm, Plasma membrane" "HPA041945: " "unprognostic (1.10e-1)" "unprognostic (3.95e-3)" "unprognostic (1.98e-2)" "unprognostic (2.59e-1)" "unprognostic (1.63e-1)" "unprognostic (1.66e-1)" "unprognostic (1.19e-1)" "unprognostic (2.11e-1)" "unprognostic (2.57e-1)" "unprognostic (1.14e-2)" "unprognostic (2.52e-3)" "unprognostic (1.29e-2)" "prognostic unfavorable (6.56e-5)" "unprognostic (6.60e-2)" "unprognostic (7.25e-2)" "prognostic favorable (1.71e-4)" "unprognostic (9.99e-2)" 21.3 24.5 17.4 40.4 17.5 61.3 18.7 19.5 17.6 24.6 20.7 37.4 58.5 18.5 18.9 25.9 27.8 22.0 11.5 17.2 19.1 20.8 51.5 28.6 44.3 21.1 19.5 21.5 23.4 17.7 15.3 25.0 21.6 21.7 32.8 8.7 30.7 21.2 7.0 27.5 58.7 22.8 20.3 40.4 32.4 15.4 19.0 34.3 16.3 8.1 45.1 25.9 21.2 23.3 94.2 62.6 50.5 43.0 42.7 36.7 77.9 56.0 48.8 74.2 76.8 76.1 105.7 66.1 61.9 58.6 63.5 60.6 71.2 69.1 50.9 132.6 39.9 135.9 57.1 75.6 46.7 119.4 129.3 36.6 37.6 69.5 32.1 38.9 63.5 65.0 64.4 97.0 63.4 111.6 100.1 113.7 63.3 114.3 100.5 111.6 56.2 115.6 58.2 71.9 46.9 45.3 56.6 68.0 35.9 34.2 53.8 44.2 61.7 61.4 39.2 119.2 96.6 51.4 113.4 97.3 58.7 121.5 67.0 244.5 278.6 315.0 164.3 387.5 145.7 190.5 143.3 147.5 247.5 190.0 112.5 131.7 292.2 225.9 485.1 177.8 150.9 514.1 17.4 17.5 19.5 17.6 17.2 19.1 21.1 19.5 21.6 20.3 19.0 23.3 47.2 25.6 29.1 2.3 70.2 47.7 47.4 53.5 31.3 15.2 37.0 34.7 3.0 17.2 35.7 31.3 14.6 95.7 97.9 115.9 82.2 70.7 31.0 33.7 29.7 37.3 30.4 47.5 4.2 51.5 98.6 36.3 29.6 45.0 48.7 36.2 26.0 50.3 88.9 6.7 3.5 55.3 48.8 50.6 81.5 19.0 27.7 100.9 33.8 2.8 124.8 34.9 131.8 3.0 8.8 76.8 90.0 24.8 96.5 30.7 130.7 62.6 35.4 13.9 32.9 22.0 38.1 33.3 23.4 30.4 52.6 79.6 64.8 43.4 52.0 38.4 RAB8B ENSG00000166128 "RAB8B, member RAS oncogene family" Q92930 15 63189560-63267776 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 81.1" "Cell type enhanced" "Detected in all" "Early spermatids: 220.6;Langerhans cells: 195.6;Late spermatids: 399.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "WM-115: 125.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 4700000 "Cluster 38: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 17: WM-115 - Nervous system development" "Cluster 24: Non-specific - Transcription regulation" "unprognostic (7.67e-2)" "unprognostic (3.33e-2)" "unprognostic (2.75e-1)" "unprognostic (1.32e-1)" "unprognostic (5.20e-2)" "unprognostic (4.01e-2)" "unprognostic (1.46e-2)" "unprognostic (5.94e-2)" "unprognostic (3.19e-1)" "unprognostic (2.75e-2)" "unprognostic (1.71e-2)" "unprognostic (4.17e-1)" "prognostic unfavorable (2.44e-4)" "unprognostic (1.97e-2)" "unprognostic (3.14e-2)" "unprognostic (4.19e-2)" "unprognostic (7.47e-2)" 26.7 14.7 10.6 30.0 12.3 81.1 13.3 11.0 13.1 19.3 14.3 12.5 18.8 17.7 8.4 13.5 10.8 24.4 12.6 12.7 12.2 12.6 15.3 22.4 43.2 10.1 12.3 32.0 7.4 7.7 5.7 30.3 11.5 14.6 11.5 12.0 7.1 10.0 5.4 7.4 17.5 18.7 13.4 34.4 13.2 15.9 13.0 37.8 21.6 10.1 38.9 27.9 9.3 15.3 13.9 12.0 43.4 18.6 82.1 67.0 12.9 13.3 30.3 24.1 46.5 12.7 11.6 38.2 11.8 29.6 26.3 7.0 37.5 18.0 40.8 54.9 7.4 45.4 9.9 8.4 76.1 17.9 28.0 40.8 9.5 45.2 26.7 31.0 60.4 37.1 19.1 36.2 44.3 9.4 27.5 10.3 27.6 12.8 11.2 24.7 57.3 5.6 19.5 66.7 3.8 9.4 20.1 2.8 39.0 27.5 9.4 19.0 68.6 44.8 27.1 24.2 18.2 23.1 24.0 34.6 28.7 50.4 125.5 62.1 26.3 22.4 26.5 23.3 23.6 18.8 20.9 25.9 18.1 17.3 15.8 20.2 56.4 25.0 22.7 2.4 35.7 30.0 10.6 12.3 11.0 13.1 12.7 12.2 10.1 12.3 11.5 13.4 13.0 15.3 32.9 19.2 13.7 18.9 71.8 31.1 7.8 18.8 12.5 2.2 14.8 10.3 5.4 11.5 12.4 7.3 12.5 13.8 140.6 2.4 11.7 37.4 220.6 4.3 28.2 29.5 10.7 19.1 23.7 13.5 102.8 58.9 14.3 8.1 39.3 11.2 33.5 6.6 56.1 20.2 45.4 4.1 14.2 76.9 195.6 399.8 31.7 79.3 35.6 40.3 142.7 13.9 97.9 64.3 62.9 33.3 1.1 38.0 37.6 11.7 11.4 32.8 10.3 14.8 19.7 15.8 29.3 71.3 17.2 7.7 22.4 37.4 105.0 16.3 3.4 22.5 RAC1 "p21-Rac1, Rac-1, TC-25" ENSG00000136238 "Rac family small GTPase 1" P63000 7 6374527-6403967 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" Hydrolase "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Urothelial cells: 1980.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB035994, HPA047820" Approved Approved Nucleoplasm,Nucleoli,Cytosol NA NA 3900000 "Cluster 26: Non-specific - Mitochondria" "Cluster 70: Brain - Nervous system development" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Cytosol" Nucleoli "CAB035994: , HPA047820: AB_2680167" "unprognostic (8.66e-3)" "unprognostic (2.47e-1)" "unprognostic (4.00e-1)" "unprognostic (2.40e-2)" "unprognostic (1.88e-3)" "unprognostic (4.06e-2)" "prognostic unfavorable (1.74e-5)" "prognostic unfavorable (4.59e-4)" "unprognostic (1.59e-1)" "unprognostic (2.04e-1)" "prognostic unfavorable (4.57e-5)" "unprognostic (3.63e-1)" "prognostic unfavorable (2.11e-4)" "unprognostic (1.95e-1)" "unprognostic (2.11e-2)" "unprognostic (4.13e-2)" "unprognostic (8.72e-3)" 157.4 108.0 237.0 96.8 250.4 94.5 146.4 242.4 290.7 154.8 206.5 190.5 167.4 150.7 149.9 316.9 145.1 125.9 129.4 240.2 240.6 150.5 136.2 147.5 96.4 249.4 244.8 135.8 92.2 151.1 77.5 180.2 249.2 122.8 199.6 52.2 137.9 145.0 179.5 189.2 161.9 179.3 260.2 96.6 160.6 51.6 241.1 115.3 127.2 141.1 169.6 205.3 188.6 262.9 519.9 230.9 233.0 255.1 270.1 341.8 138.6 284.9 348.0 371.6 375.8 227.3 474.8 145.5 179.7 400.9 384.2 359.4 251.5 345.9 471.9 68.3 207.8 146.6 171.7 166.5 323.7 134.0 114.6 229.7 302.8 268.4 297.6 281.7 333.4 141.3 266.2 111.7 406.4 377.3 74.0 312.4 419.1 261.9 272.3 129.2 236.9 214.6 481.7 322.7 175.8 295.9 201.7 726.1 241.4 264.7 409.6 396.3 341.8 242.4 364.3 300.7 334.5 84.1 99.5 135.4 223.9 250.9 470.6 31.0 117.3 63.0 23.8 83.0 15.1 46.8 26.8 30.9 112.8 49.9 33.0 21.8 168.6 26.1 83.5 64.5 46.1 47.0 237.0 250.4 242.4 290.7 240.2 240.6 249.4 244.8 249.2 260.2 241.1 262.9 755.4 147.4 123.6 28.7 155.9 934.1 981.6 232.1 429.2 90.4 485.3 593.8 200.6 484.7 164.8 356.8 25.0 802.8 224.1 920.9 536.1 183.5 77.6 388.7 362.9 641.2 336.7 313.3 43.3 174.2 1064.1 415.9 305.3 422.8 130.9 325.4 580.8 367.1 832.0 146.4 35.3 632.9 179.0 811.3 1066.7 58.8 476.3 705.7 458.9 66.5 607.2 341.1 191.6 23.1 56.7 299.1 754.4 472.8 212.2 1495.5 816.4 832.0 214.1 64.2 479.9 346.6 466.6 216.6 373.1 774.5 1148.6 845.4 180.0 353.6 573.7 1980.7 RAE1 "Gle2, Mnrp41" ENSG00000101146 "Ribonucleic acid export 1" P78406 20 57351223-57379211 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 103.0" "Cell type enhanced" "Detected in all" "Early spermatids: 113.6;Spermatocytes: 256.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048795 Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Nucleoli fibrillar center" "HPA048795: AB_2680523" "unprognostic (1.20e-1)" "unprognostic (5.98e-2)" "unprognostic (4.55e-2)" "prognostic unfavorable (2.44e-4)" "unprognostic (3.23e-1)" "unprognostic (2.04e-1)" "prognostic unfavorable (2.12e-7)" "unprognostic (1.88e-1)" "unprognostic (8.26e-2)" "unprognostic (1.22e-1)" "unprognostic (5.50e-3)" "unprognostic (3.88e-2)" "unprognostic (7.48e-2)" "unprognostic (3.55e-1)" "unprognostic (9.49e-2)" "unprognostic (2.89e-1)" "unprognostic (2.01e-1)" 14.0 13.9 18.6 13.5 19.1 50.5 17.0 18.5 19.1 15.5 17.6 14.2 11.9 16.6 18.2 20.5 17.4 9.0 13.3 18.3 19.9 14.1 16.5 10.0 20.8 16.3 15.9 16.3 10.8 19.1 13.3 14.6 17.0 12.4 16.2 20.1 12.8 15.0 15.0 22.9 13.6 16.3 17.2 17.0 12.8 103.0 21.4 29.2 12.1 15.8 26.5 14.5 16.0 19.6 43.5 52.6 52.8 29.3 30.1 29.0 46.1 33.9 47.2 172.2 70.3 166.1 33.8 69.2 46.8 52.8 63.8 56.6 101.6 88.3 142.1 20.8 45.2 47.0 46.0 74.9 59.0 57.1 41.3 41.3 74.0 75.8 83.1 29.1 49.9 47.2 84.8 32.5 53.0 114.8 88.3 53.2 32.9 86.3 93.3 47.6 49.4 46.0 37.3 45.5 55.2 47.6 58.4 129.4 61.0 41.2 71.5 54.0 29.7 70.6 63.0 41.7 57.7 34.9 83.9 81.8 48.3 36.1 35.6 21.2 42.0 77.0 27.0 36.8 32.9 31.2 26.0 26.8 32.3 28.1 33.9 30.7 36.2 24.7 37.9 23.8 24.6 40.4 18.6 19.1 18.5 19.1 18.3 19.9 16.3 15.9 17.0 17.2 21.4 19.6 17.5 19.2 16.7 8.5 21.0 17.2 16.3 42.0 15.9 15.9 12.6 19.3 10.4 11.5 24.1 18.4 14.6 52.8 20.8 11.6 27.4 30.3 113.6 16.5 16.7 17.9 6.6 18.7 10.2 14.3 39.3 18.6 12.2 15.3 38.0 25.6 11.0 13.5 38.3 3.3 9.5 15.2 18.3 59.5 14.5 63.9 21.8 33.5 10.6 14.0 40.0 19.9 27.8 5.5 13.1 22.2 24.3 22.6 15.9 14.0 10.1 20.6 24.1 17.9 19.7 11.6 19.9 256.9 83.1 19.2 21.0 70.5 24.2 34.9 20.1 16.2 RAET1E "bA350J20.7, LETAL, ULBP4" ENSG00000164520 "Retinoic acid early transcript 1E" Q8TD07 6 149883375-149898102 "Predicted intracellular proteins, Predicted membrane proteins" Immunity "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 21.9;esophagus: 62.8;skin 1: 21.6;vagina: 27.5" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 12.4;Early spermatids: 10.0;Late spermatids: 5.6;Respiratory ciliated cells: 14.6;Squamous epithelial cells: 17.2;Suprabasal keratinocytes: 6.5" "Cancer enhanced" "Detected in many" "head and neck cancer: 3.9" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HBEC3-KT: 19.6;HeLa: 24.4;hTCEpi: 19.1;SiHa: 9.9;U-87 MG: 7.7" HPA054022 Supported "Focal adhesion sites,Cytosol" "Intracellular and membrane" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 20: HeLa - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "Focal adhesion sites" Cytosol "HPA054022: AB_2797250" "unprognostic (1.67e-2)" "unprognostic (2.10e-1)" "unprognostic (3.49e-3)" "unprognostic (1.26e-1)" "unprognostic (1.36e-1)" "unprognostic (2.71e-2)" "unprognostic (1.36e-3)" "unprognostic (4.80e-4)" "unprognostic (1.11e-1)" "unprognostic (3.39e-1)" "unprognostic (1.02e-1)" "unprognostic (1.69e-1)" "unprognostic (7.47e-5)" "unprognostic (2.41e-2)" "unprognostic (3.18e-2)" "unprognostic (3.17e-2)" "unprognostic (1.06e-1)" 3.7 0.8 0.6 0.1 0.4 0.1 1.9 1.0 0.7 21.9 0.8 0.2 0.1 0.3 0.0 62.8 0.8 0.1 0.5 0.5 0.5 2.2 0.1 0.3 0.1 0.4 0.3 0.1 0.1 0.0 0.2 0.5 0.5 0.3 0.3 0.1 12.9 0.3 1.6 21.6 0.1 0.5 0.1 0.9 0.3 0.4 0.4 0.1 0.3 0.2 11.6 1.9 27.5 0.5 1.8 1.0 0.0 0.0 0.2 1.3 0.0 0.1 0.9 0.1 0.3 0.0 4.3 0.0 2.6 4.4 1.4 1.7 0.0 19.6 0.2 0.3 0.0 0.1 24.4 0.0 0.0 0.0 0.0 0.4 19.1 1.0 3.9 0.4 0.1 0.1 0.0 1.3 0.8 0.0 0.0 0.0 0.1 0.3 0.8 0.0 0.0 0.3 0.4 0.9 0.2 0.0 9.9 1.5 0.0 0.0 1.2 0.0 1.8 0.8 0.3 0.2 0.9 0.0 0.0 0.0 7.7 0.4 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.4 1.0 0.7 0.5 0.5 0.4 0.3 0.5 0.1 0.4 0.5 1.0 0.0 0.0 0.3 0.0 2.2 1.1 12.4 1.8 0.6 0.3 0.6 0.3 1.5 3.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 10.0 2.5 0.1 1.0 0.0 0.0 0.9 0.0 0.0 2.0 0.0 0.1 0.0 0.0 0.7 0.0 0.1 0.0 1.1 0.1 0.0 0.0 0.3 5.6 0.0 0.0 0.0 1.9 0.0 0.2 0.0 0.5 1.1 0.4 0.0 0.0 0.0 0.2 0.0 0.0 14.6 0.4 0.0 0.3 0.4 0.0 0.2 17.2 6.5 0.0 0.2 0.1 0.2 1.6 RAPGEF3 "bcm910, cAMP-GEFI, EPAC" ENSG00000079337 "Rap guanine nucleotide exchange factor 3" O95398 12 47734363-47771040 "Predicted intracellular proteins" Angiogenesis "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 130.6;Astrocytes: 143.0;Collecting duct cells: 69.9;Endothelial cells: 53.0;Oligodendrocytes: 45.7" "Cancer enhanced" "Detected in all" "thyroid cancer: 13.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 26.9;HUVEC TERT2: 12.1;NB-4: 14.3;RPTEC TERT1: 13.3;TIME: 12.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004386, HPA040365, HPA043518" Approved Uncertain "Endoplasmic reticulum,Cytosol" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "Endoplasmic reticulum" "CAB004386: AB_627521, HPA040365: AB_2676941, HPA043518: AB_2678524" "unprognostic (2.12e-1)" "unprognostic (2.88e-2)" "unprognostic (2.99e-2)" "unprognostic (1.81e-2)" "unprognostic (1.88e-1)" "unprognostic (1.82e-2)" "unprognostic (1.23e-4)" "unprognostic (9.35e-2)" "unprognostic (1.25e-2)" "unprognostic (5.32e-3)" "unprognostic (4.67e-2)" "unprognostic (4.37e-2)" "prognostic favorable (6.67e-7)" "unprognostic (9.16e-2)" "unprognostic (2.92e-1)" "unprognostic (2.61e-3)" "unprognostic (3.38e-2)" 44.6 2.8 29.2 2.6 35.0 1.4 44.0 30.3 29.2 26.0 12.5 9.9 4.0 16.4 6.9 13.2 24.1 13.2 21.1 31.4 21.3 40.0 1.9 11.9 4.4 33.6 29.6 38.2 4.7 5.8 6.4 8.9 28.0 13.5 2.4 0.9 21.2 11.0 11.4 9.8 8.8 5.1 22.4 16.2 11.5 3.5 28.9 1.6 32.4 9.0 2.1 14.9 21.3 39.7 2.3 0.6 0.7 2.4 0.3 2.3 0.9 1.7 1.5 0.7 0.4 0.3 6.1 0.1 26.9 3.0 1.1 2.4 0.8 4.5 0.3 3.0 0.4 0.2 2.6 0.2 0.2 0.4 0.3 0.9 0.3 1.3 0.8 3.4 12.1 0.6 0.1 2.9 0.5 1.5 0.0 14.3 0.6 1.0 3.7 0.4 0.1 1.0 13.3 2.5 0.2 0.3 0.2 1.7 0.4 0.8 6.7 0.6 12.0 6.6 1.1 1.5 0.6 1.0 0.4 0.2 4.1 3.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.2 35.0 30.3 29.2 31.4 21.3 33.6 29.6 28.0 22.4 28.9 39.7 130.6 0.0 11.7 143.0 0.7 2.7 5.8 2.6 13.1 0.5 4.5 4.8 15.7 2.8 3.6 69.9 0.0 0.2 1.4 1.7 7.9 1.1 1.6 11.8 2.4 53.0 0.0 0.0 1.5 0.7 0.4 6.3 18.3 21.2 3.8 1.5 20.7 0.2 0.9 0.0 2.9 6.6 4.1 0.6 2.6 3.7 24.2 1.5 5.4 12.2 0.0 1.5 2.1 10.6 45.7 5.8 6.3 8.6 4.4 11.6 0.8 41.3 1.9 0.5 6.6 2.7 5.1 1.2 1.6 1.4 3.3 0.3 1.3 6.6 0.8 17.2 RARRES1 "LXNL, TIG1" ENSG00000118849 "Retinoic acid receptor responder 1" P49788 3 158696892-158732489 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 221.9;fallopian tube: 206.4" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 217.1;Club cells: 621.4;Prostatic glandular cells: 312.9;Urothelial cells: 737.7" "Cancer enhanced" "Detected in all" "urothelial cancer: 93.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 10 "CAPAN-2: 1319.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003892 Uncertain Approved "Endoplasmic reticulum,Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Golgi apparatus" "Endoplasmic reticulum" "HPA003892: AB_1856079" "unprognostic (5.76e-3)" "unprognostic (2.13e-1)" "unprognostic (8.85e-2)" "unprognostic (1.19e-2)" "prognostic unfavorable (9.29e-4)" "unprognostic (7.09e-2)" "unprognostic (8.93e-2)" "unprognostic (3.86e-1)" "unprognostic (7.16e-3)" "unprognostic (1.47e-2)" "unprognostic (6.42e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (5.88e-6)" "unprognostic (3.49e-1)" "unprognostic (1.33e-1)" "unprognostic (7.73e-2)" "unprognostic (1.15e-1)" 221.9 21.3 1.0 65.1 1.5 0.6 44.6 1.5 1.7 74.6 11.3 31.7 5.1 25.9 27.0 11.3 206.4 19.7 81.5 1.5 0.8 25.1 4.2 52.7 18.9 0.6 0.4 60.5 10.0 0.2 27.7 3.5 0.4 78.6 36.2 0.9 165.3 37.2 5.6 8.3 38.5 51.2 0.4 2.7 23.7 4.5 1.0 1.8 20.4 2.8 6.2 92.1 32.2 1.4 19.2 6.9 0.2 1.0 4.0 12.6 0.3 1.8 5.7 1.0 1.4 1.4 1319.3 0.0 1.2 0.9 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 2.0 0.1 12.0 0.0 0.0 131.3 0.0 0.5 0.0 8.9 2.8 0.0 0.0 0.0 0.4 0.0 0.0 0.2 1.7 5.8 0.0 0.0 0.0 0.1 0.3 22.9 0.5 1.7 16.7 1.3 0.3 0.0 1.9 2.3 1.3 1.1 0.0 4.6 0.0 0.0 0.0 0.0 1.5 0.1 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 1.0 1.5 1.5 1.7 1.5 0.8 0.6 0.4 0.4 0.4 1.0 1.4 5.2 0.0 0.6 2.3 0.9 0.5 217.1 92.7 11.4 0.4 99.7 35.6 0.9 11.5 621.4 14.7 0.0 2.9 1.6 59.0 0.0 10.5 29.5 14.4 98.4 18.1 37.5 3.6 14.2 4.7 0.8 101.3 1.1 16.9 29.9 0.3 31.8 6.0 10.8 0.0 10.6 102.3 40.7 1.6 1.7 33.1 10.8 11.0 5.4 1.9 0.0 4.2 0.0 4.5 7.6 2.3 106.1 1.2 1.2 312.9 140.7 19.7 149.3 0.7 0.0 7.7 46.7 3.8 0.7 7.8 0.4 11.4 3.3 0.1 88.3 737.7 RASGRF2 "GRF2, Ras-GRF2" ENSG00000113319 "Ras protein specific guanine nucleotide releasing factor 2" O14827 5 80960363-81230162 "Predicted intracellular proteins, RAS pathway related proteins" "Calmodulin-binding, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 22.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 220.6;Inhibitory neurons: 407.6;Microglial cells: 89.0;Oligodendrocytes: 395.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 1.9;MAIT T-cell: 5.2;memory CD4 T-cell: 2.6;memory CD8 T-cell: 1.5;naive CD4 T-cell: 4.2;naive CD8 T-cell: 3.0" "Lineage enriched" "Detected in single" 52 "T-cells: 5.2" "Cell line enhanced" "Detected in some" "BEWO: 37.8;CACO-2: 23.3;Hep G2: 31.8;HHSteC: 20.8;hTERT-RPE1: 15.3;SuSa: 16.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 4 "amygdala: 24.5;cerebral cortex: 77.3;hippocampal formation: 46.6;olfactory bulb: 27.0" HPA018679 Uncertain Supported "Endoplasmic reticulum" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 28: BEWO - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Endoplasmic reticulum" "HPA018679: AB_1856089" "unprognostic (1.32e-1)" "unprognostic (6.96e-2)" "unprognostic (7.27e-2)" "unprognostic (7.80e-2)" "unprognostic (3.62e-1)" "unprognostic (1.00e-1)" "unprognostic (5.76e-3)" "unprognostic (2.58e-1)" "unprognostic (4.02e-1)" "unprognostic (8.51e-2)" "unprognostic (8.13e-2)" "unprognostic (1.34e-1)" "unprognostic (1.47e-3)" "unprognostic (1.37e-3)" "unprognostic (2.13e-2)" "unprognostic (5.01e-2)" "unprognostic (1.12e-1)" 11.2 0.9 10.5 3.4 9.4 1.0 7.3 1.2 14.9 3.4 16.1 2.9 1.8 2.4 0.8 1.3 2.2 5.2 5.4 11.6 4.8 4.8 0.5 3.3 3.5 3.4 2.2 17.6 1.0 2.3 4.1 10.2 2.5 3.6 1.4 22.9 1.5 1.5 2.7 1.1 2.4 2.6 5.1 2.2 1.8 2.0 13.8 1.5 4.7 6.8 2.8 3.4 2.4 10.0 0.0 2.1 0.5 0.3 0.0 0.0 37.8 0.7 9.3 0.4 0.4 23.3 0.0 0.4 11.9 0.0 0.2 0.6 0.0 0.0 1.2 0.6 4.0 0.2 0.3 31.8 20.8 0.0 0.0 1.0 0.1 8.8 0.1 15.3 0.2 0.5 0.0 0.1 0.0 0.3 0.3 0.2 4.5 0.0 0.1 0.2 4.5 0.1 1.4 0.0 0.4 0.5 0.1 0.0 0.3 16.2 0.0 0.1 0.1 0.0 0.2 0.2 0.1 0.1 0.1 0.3 0.2 0.1 0.4 0.0 0.0 0.0 1.9 0.0 5.2 0.0 2.6 1.5 0.0 0.0 4.2 3.0 0.0 0.0 0.0 0.0 0.7 1.0 10.5 9.4 1.2 14.9 11.6 4.8 3.4 2.2 2.5 5.1 13.8 10.0 45.3 0.0 1.1 10.1 0.6 1.7 0.3 0.1 0.0 15.9 0.2 0.3 5.2 0.0 0.6 9.2 58.4 1.1 2.2 0.2 0.0 0.4 10.2 1.3 0.3 23.7 0.0 0.0 220.6 0.0 26.9 2.5 0.5 1.1 0.0 0.2 5.3 0.1 1.1 1.7 407.6 0.5 0.0 0.3 0.8 3.0 0.9 0.5 1.8 89.0 0.2 3.7 6.2 8.5 395.6 0.7 1.2 9.1 0.9 0.3 1.0 2.1 0.0 42.1 0.0 1.5 0.9 6.7 1.6 0.3 0.6 0.8 7.5 4.1 1.3 0.5 RASGRP1 "CalDAG-GEFII, RASGRP" ENSG00000172575 "RAS guanyl releasing protein 1" O95267 15 38488103-38565575 "Disease related genes, Predicted intracellular proteins, RAS pathway related proteins" Differentiation "Guanine-nucleotide releasing factor" "Disease variant, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.7;lymphoid tissue: 45.7;retina: 29.7" "Cell type enhanced" "Detected in many" "dendritic cells: 71.4;Excitatory neurons: 54.1;Muller glia cells: 86.9;Plasma cells: 43.0;T-cells: 84.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "T-reg: 10.3" "Lineage enriched" "Detected in many" 4 "T-cells: 10.3" "Group enriched" "Detected in many" 4 "HDLM-2: 54.5;JURKAT: 70.2;MOLT-4: 52.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039389 Supported "Plasma membrane,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" Cytosol "Plasma membrane" "HPA039389: AB_2732481" "unprognostic (3.44e-3)" "unprognostic (1.86e-2)" "unprognostic (1.17e-2)" "unprognostic (3.43e-3)" "unprognostic (1.82e-2)" "unprognostic (3.33e-3)" "unprognostic (9.63e-2)" "unprognostic (4.23e-2)" "unprognostic (1.91e-1)" "unprognostic (1.21e-1)" "unprognostic (4.50e-1)" "unprognostic (3.01e-2)" "unprognostic (2.54e-1)" "unprognostic (2.55e-1)" "unprognostic (1.51e-1)" "unprognostic (3.40e-1)" "unprognostic (9.30e-2)" 1.1 0.8 6.7 10.5 16.8 8.5 1.7 23.7 13.2 0.8 0.0 1.4 2.4 1.4 0.4 5.9 4.4 2.5 1.2 11.6 3.3 5.5 1.1 4.1 21.4 15.3 2.5 0.4 1.8 0.5 0.5 0.9 17.9 0.7 2.1 29.7 1.7 0.7 0.4 6.9 3.6 0.6 0.0 8.9 4.5 2.0 8.8 45.7 0.6 0.7 16.4 3.4 2.0 9.2 0.0 0.4 1.0 0.3 0.0 0.0 0.1 4.1 1.2 2.0 1.7 4.5 0.0 11.6 0.9 0.1 0.2 0.2 2.4 0.0 1.9 54.5 2.2 0.9 0.5 0.0 0.6 0.5 0.8 0.0 0.1 1.1 0.0 0.0 0.0 70.2 0.5 3.6 0.0 1.7 52.3 0.1 0.7 0.0 0.0 14.4 0.3 0.0 2.0 0.1 4.7 1.7 2.6 0.1 0.2 1.5 1.2 0.0 0.2 0.4 1.6 5.6 0.8 8.7 4.6 13.6 0.2 0.1 0.6 0.0 0.0 0.9 5.2 0.0 3.7 1.1 5.7 5.2 0.0 0.6 5.2 5.3 0.2 2.4 0.0 0.0 10.3 1.4 6.7 16.8 23.7 13.2 11.6 3.3 15.3 2.5 17.9 0.0 8.8 9.2 0.9 6.4 10.7 6.5 26.5 2.4 0.4 6.8 4.6 9.6 3.4 2.0 4.5 5.7 2.7 33.1 10.4 0.3 71.4 0.1 3.9 18.4 1.5 7.6 1.6 0.8 0.0 0.0 54.1 10.0 0.2 1.2 1.1 6.6 3.8 0.4 1.1 0.5 0.7 6.7 16.5 1.3 0.0 0.8 6.1 0.7 0.0 3.0 7.2 9.4 3.0 86.9 34.0 2.5 3.9 34.1 0.0 0.0 43.0 0.7 0.3 7.8 0.4 21.3 0.0 1.9 1.3 1.2 3.8 4.0 8.2 0.0 84.7 0.3 0.9 0.5 RASL12 RIS ENSG00000103710 "RAS like family 12" Q9NYN1 15 65053337-65076690 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 22.5;Peritubular cells: 57.9;Sertoli cells: 98.6;Smooth muscle cells: 55.7" "Cancer enhanced" "Detected in all" "glioma: 21.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 5.0;CACO-2: 14.5;EFO-21: 22.7;NTERA-2: 9.9;SuSa: 17.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" "unprognostic (6.13e-3)" "unprognostic (1.06e-1)" "unprognostic (2.47e-2)" "unprognostic (6.95e-2)" "unprognostic (1.39e-1)" "unprognostic (1.21e-2)" "unprognostic (4.10e-2)" "unprognostic (1.40e-1)" "unprognostic (1.29e-3)" "unprognostic (1.60e-1)" "unprognostic (4.45e-2)" "unprognostic (1.51e-1)" "prognostic unfavorable (7.20e-5)" "unprognostic (1.76e-2)" "unprognostic (4.72e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (2.17e-4)" 27.9 3.9 32.9 5.1 36.8 0.0 15.7 30.8 24.4 49.8 8.5 35.6 3.6 61.6 27.9 19.2 54.7 13.2 53.4 26.0 38.4 6.9 1.1 38.4 3.3 39.4 57.4 16.5 2.4 1.8 7.0 17.0 38.0 52.5 6.7 3.3 8.0 76.4 37.1 12.1 9.4 33.0 38.8 9.6 7.7 15.6 66.1 0.9 8.4 20.6 1.7 40.2 33.5 32.6 0.1 0.1 0.2 0.0 0.6 5.0 0.2 0.0 0.5 0.0 0.0 14.5 0.1 0.0 22.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 9.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 17.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.9 36.8 30.8 24.4 26.0 38.4 39.4 57.4 38.0 38.8 66.1 32.6 7.4 0.0 0.0 22.5 0.0 1.5 3.9 0.0 0.0 0.3 2.0 5.6 16.3 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 4.7 0.3 12.6 3.6 0.0 0.0 0.1 0.0 0.1 15.2 0.5 0.5 0.0 12.3 1.4 0.1 0.3 0.0 0.1 0.0 2.0 0.0 1.3 3.9 13.1 0.2 0.0 2.8 0.0 17.9 0.0 0.0 0.0 0.1 0.0 57.9 0.0 0.4 0.5 0.0 0.0 0.8 98.6 0.9 55.7 0.7 1.1 0.4 0.1 0.3 0.2 0.4 0.2 0.1 RBBP5 "RBQ3, SWD1" ENSG00000117222 "RB binding protein 5, histone lysine methyltransferase complex subunit" Q15291 1 205086142-205122015 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049042, HPA058085" Uncertain Supported Nucleoplasm,Nucleoli No No "Cluster 38: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Nucleoli" "HPA049042: AB_2680610, HPA058085: AB_2683600" "unprognostic (8.72e-2)" "unprognostic (6.35e-2)" "unprognostic (2.14e-2)" "unprognostic (1.36e-2)" "unprognostic (1.60e-1)" "unprognostic (1.17e-1)" "unprognostic (4.61e-3)" "unprognostic (1.24e-1)" "unprognostic (3.07e-2)" "unprognostic (2.88e-1)" "unprognostic (2.75e-1)" "unprognostic (4.98e-2)" "unprognostic (6.90e-2)" "unprognostic (3.78e-3)" "unprognostic (4.95e-2)" "unprognostic (1.28e-1)" "unprognostic (4.88e-2)" 6.3 8.2 4.7 7.2 5.3 9.5 7.9 6.4 6.4 7.8 2.7 7.0 7.1 8.1 7.5 7.0 7.5 6.1 6.4 5.7 5.3 12.4 11.0 6.6 11.3 3.4 3.8 9.5 8.2 9.4 6.1 6.5 3.8 6.9 8.0 9.8 7.6 6.9 8.7 8.5 6.7 7.1 4.3 9.3 6.7 6.1 4.5 13.2 9.8 9.9 12.8 7.5 5.2 6.4 16.3 16.9 16.0 19.0 21.8 12.5 17.3 15.2 12.9 19.0 18.8 17.9 19.1 25.3 11.3 11.1 15.5 18.2 26.9 10.1 22.4 21.6 14.5 21.2 16.4 14.6 14.1 26.9 16.6 10.1 12.9 17.6 15.0 12.7 15.4 17.9 41.6 25.2 16.0 15.0 26.1 11.3 26.1 14.2 27.9 22.9 33.9 31.6 13.2 11.7 25.0 20.1 21.3 22.3 19.2 19.0 24.2 14.9 11.8 15.6 16.6 23.1 20.2 12.2 18.3 30.6 13.9 16.5 24.5 22.0 4.9 7.9 8.0 6.4 8.5 7.8 7.4 8.1 5.4 6.2 7.1 8.7 11.6 8.2 8.3 6.0 8.1 3.5 4.7 5.3 6.4 6.4 5.7 5.3 3.4 3.8 3.8 4.3 4.5 6.4 14.7 19.2 12.2 11.4 31.0 26.9 9.7 5.9 15.9 14.5 18.9 14.6 7.1 8.6 13.4 22.0 29.2 9.1 25.2 15.8 9.8 12.1 7.3 13.1 14.0 13.2 12.1 23.1 19.9 11.6 10.7 13.5 9.7 21.0 13.9 25.6 17.2 21.8 10.9 16.8 15.7 14.0 10.2 15.6 25.9 3.2 12.8 17.9 19.6 8.4 15.6 12.6 15.5 14.6 21.2 13.6 9.8 16.1 25.9 13.5 14.7 28.8 13.2 18.3 19.7 21.9 14.1 10.2 20.4 14.6 33.8 10.8 27.9 12.6 15.8 13.4 RBP4 ENSG00000138207 "Retinol binding protein 4" P02753 10 93591687-93601744 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Sensory transduction, Transport, Vision" "Cancer-related genes, Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 16 "liver: 11920.3" "Cell type enriched" "Detected in many" 12 "Hepatocytes: 12711.6" "Cancer enriched" "Detected in all" 27 "liver cancer: 3135.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "Hep G2: 1117.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA001641, CAB004555" Supported "Secreted to blood" NA NA 46100000000 210000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "CAB004555: AB_670938, HPA001641: AB_1079795" "unprognostic (9.42e-3)" "unprognostic (3.40e-2)" "unprognostic (1.90e-1)" "prognostic unfavorable (1.50e-4)" "unprognostic (2.60e-2)" "unprognostic (6.69e-4)" "prognostic favorable (1.74e-8)" "unprognostic (2.39e-1)" "unprognostic (5.76e-2)" "unprognostic (3.26e-2)" "unprognostic (3.26e-1)" "unprognostic (3.44e-1)" "unprognostic (7.14e-3)" "unprognostic (9.88e-3)" "unprognostic (2.31e-1)" "unprognostic (1.03e-1)" "unprognostic (8.60e-2)" 730.7 32.4 30.2 6.2 34.4 1.1 394.2 12.4 48.1 5.8 12.4 11.2 4.8 2.3 0.9 1.1 2.1 7.5 16.7 32.2 113.0 142.8 11920.3 24.5 0.6 21.5 19.3 4.1 82.4 0.1 519.9 12.4 21.3 8.6 6.7 3.0 13.7 4.6 6.2 16.4 19.2 0.8 14.9 5.5 11.9 4.7 46.2 1.5 7.9 5.3 0.1 19.0 8.8 18.0 0.0 14.7 0.0 0.0 2.9 0.0 0.1 0.3 0.1 2.5 0.4 264.9 0.5 1.5 2.7 0.3 0.2 0.8 0.0 0.0 0.3 0.2 0.2 2.2 1.1 1117.2 0.2 9.2 0.2 18.7 0.5 0.7 0.0 0.0 0.0 0.0 1.4 0.2 1.2 0.0 0.1 7.3 1.3 2.4 121.7 0.4 7.0 0.0 0.0 0.6 0.9 0.2 9.6 0.0 0.0 0.6 0.5 0.8 0.4 0.0 7.8 0.2 0.3 0.9 0.3 3.7 0.0 3.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.2 34.4 12.4 48.1 32.2 113.0 21.5 19.3 21.3 14.9 46.2 18.0 9.1 0.0 4.2 0.3 17.2 0.8 0.5 0.0 0.0 0.0 2.1 6.7 0.7 999.4 0.6 23.9 6.2 0.3 0.2 21.9 97.8 7.8 2.8 1.6 3.1 10.8 62.5 152.4 5.8 0.2 22.6 10.5 0.0 22.1 0.0 0.0 158.1 12711.6 17.8 0.0 7.2 40.7 0.0 210.4 3.0 2.4 3.1 7.8 1.8 1.0 0.0 0.8 0.0 1.0 1.1 29.2 28.0 5.7 0.3 2.1 0.8 785.3 0.7 0.5 0.0 7.3 3.8 3.1 13.9 0.0 0.9 1.4 12.3 0.0 1.7 1.4 RDH11 "ARSDR1, MDT1, SDR7C1" ENSG00000072042 "Retinol dehydrogenase 11" Q8TC12 14 67676800-67695793 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Cataract, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "prostate: 582.0" "Cell type enhanced" "Detected in all" "Hepatocytes: 241.8;Muller glia cells: 299.7;Prostatic glandular cells: 285.7" "Cancer enriched" "Detected in all" 13 "prostate cancer: 286.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB046011 Enhanced "Intracellular and membrane" NA NA 340000 "Cluster 46: Basophils - DNA binding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 5: Muller glia cells - Visual perception" "CAB046011: AB_11129613" "unprognostic (1.38e-1)" "unprognostic (6.86e-3)" "unprognostic (1.77e-1)" "prognostic favorable (2.62e-4)" "unprognostic (6.06e-2)" "prognostic unfavorable (2.89e-5)" "unprognostic (9.29e-2)" "unprognostic (1.98e-1)" "unprognostic (1.05e-1)" "unprognostic (3.58e-2)" "unprognostic (2.91e-2)" "unprognostic (1.27e-1)" "prognostic favorable (1.30e-7)" "unprognostic (1.65e-1)" "unprognostic (1.68e-1)" "unprognostic (2.18e-1)" "unprognostic (4.74e-2)" 23.6 59.5 39.3 24.5 43.2 13.9 28.7 50.2 54.4 32.6 35.9 29.2 34.1 33.2 86.0 34.6 23.5 42.7 17.6 40.4 47.2 106.0 153.1 34.9 20.4 49.2 47.7 28.9 42.6 79.8 23.4 21.9 49.3 582.0 31.4 73.9 44.2 34.4 8.3 31.4 23.9 43.6 49.8 22.2 31.9 28.4 46.1 30.7 61.7 13.5 26.2 34.3 30.3 58.4 183.7 81.9 71.3 82.0 111.5 100.4 59.3 68.0 134.2 83.7 150.9 68.6 216.7 31.7 51.2 64.6 104.8 142.5 104.0 150.8 113.7 63.0 42.6 65.1 40.7 69.0 106.9 24.3 46.0 94.4 98.0 109.3 92.0 63.9 97.4 87.0 52.1 101.1 77.2 97.5 72.2 38.8 40.4 49.7 92.8 53.6 87.4 45.8 194.1 93.0 73.8 62.0 71.2 89.7 99.1 58.2 100.7 38.3 74.2 89.5 101.1 38.9 49.5 47.5 40.0 40.7 115.8 66.0 74.3 282.4 71.1 104.0 62.3 57.7 68.2 39.0 67.7 61.5 51.3 45.5 67.3 64.8 11.0 56.3 65.4 59.1 65.1 115.8 39.3 43.2 50.2 54.4 40.4 47.2 49.2 47.7 49.3 49.8 46.1 58.4 27.0 25.6 66.0 38.2 29.2 11.5 40.0 77.9 16.5 53.5 45.4 24.5 20.4 68.6 59.9 47.8 50.1 24.9 32.4 26.8 7.9 92.5 2.5 21.9 50.9 39.3 43.3 29.2 33.3 84.0 38.1 37.5 19.9 38.2 29.2 46.3 47.8 241.8 35.8 79.1 37.6 28.9 89.5 42.4 15.4 6.1 43.2 35.9 35.6 17.8 39.8 299.7 37.0 70.4 43.4 61.2 36.7 56.1 27.3 285.7 17.5 56.0 23.9 97.0 46.0 29.7 38.7 25.8 24.0 20.2 19.2 63.5 29.8 66.7 25.3 46.1 RGMB "DRAGON, FLJ90406" ENSG00000174136 "Repulsive guidance molecule BMP co-receptor b" Q6NW40 5 98768650-98798643 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 63.9;Undifferentiated cells: 88.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 3.3" "Group enriched" "Detected in many" 12 "B-cells: 1.6;T-cells: 3.3" "Cell line enhanced" "Detected in many" "BJ: 285.8;BJ hTERT+: 142.9;fHDF/TERT166: 178.0;HBF TERT88: 222.5;LHCN-M2: 167.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016993 Approved Nucleoplasm NA NA 560000 "Cluster 32: T-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA016993: AB_1856216" "unprognostic (1.50e-2)" "unprognostic (3.77e-2)" "unprognostic (9.03e-2)" "unprognostic (8.92e-2)" "unprognostic (2.88e-1)" "unprognostic (5.27e-2)" "unprognostic (7.44e-2)" "unprognostic (1.60e-2)" "unprognostic (8.24e-2)" "unprognostic (2.19e-1)" "unprognostic (3.60e-3)" "unprognostic (9.00e-2)" "unprognostic (3.88e-2)" "unprognostic (3.90e-2)" "unprognostic (6.40e-2)" "unprognostic (4.20e-2)" "unprognostic (3.78e-3)" 8.8 7.7 14.8 7.2 18.4 0.3 9.1 11.4 17.4 9.3 5.7 20.5 21.4 9.2 6.0 11.8 11.1 7.5 10.2 17.4 15.1 4.7 6.0 8.1 3.7 12.9 16.0 21.8 11.2 9.3 11.4 5.5 27.1 20.7 33.3 3.8 21.8 13.9 24.8 33.8 26.2 10.9 12.2 6.0 41.7 10.5 22.3 2.6 11.5 16.1 4.5 10.8 9.5 14.9 7.3 5.2 87.8 8.1 26.2 44.5 9.1 285.8 142.9 138.5 97.6 4.4 3.5 4.2 10.2 178.0 9.7 7.5 10.4 26.0 222.5 12.5 10.2 0.0 7.1 4.9 12.6 0.9 0.1 37.1 9.4 71.1 28.2 37.6 26.3 13.6 0.0 3.5 167.1 8.1 0.1 0.1 6.0 3.3 14.0 11.4 50.7 7.9 5.4 8.4 35.6 18.0 3.9 9.4 14.1 4.4 7.5 0.4 57.4 86.7 14.2 54.1 133.5 6.0 9.1 5.8 31.9 0.1 19.1 0.0 0.0 0.2 0.1 0.0 0.7 1.1 1.5 0.6 0.0 1.6 3.3 1.5 0.1 0.1 0.0 0.0 2.4 0.8 14.8 18.4 11.4 17.4 17.4 15.1 12.9 16.0 27.1 12.2 22.3 14.9 8.6 16.0 4.1 7.5 12.7 31.0 15.3 6.0 44.3 5.7 17.8 12.4 14.3 7.2 5.3 9.2 16.7 4.5 0.4 12.8 1.9 5.0 63.9 10.2 12.7 10.3 21.8 0.0 20.8 5.3 6.2 19.1 18.8 18.0 0.0 4.0 9.3 8.2 2.1 0.0 23.6 44.6 4.1 1.0 7.2 16.9 9.0 2.4 12.4 5.6 0.7 1.7 0.0 35.2 6.6 8.4 16.3 7.2 1.7 16.1 11.9 1.6 6.1 4.0 0.0 20.3 13.1 7.4 17.5 27.0 24.4 1.8 2.9 5.4 88.9 17.4 RGS12 ENSG00000159788 "Regulator of G protein signaling 12" O14924 4 3293028-3439913 "Plasma proteins, Predicted intracellular proteins" Transcription "GTPase activation, Repressor, Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 46.6" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 142.0;Inhibitory neurons: 170.1;Suprabasal keratinocytes: 110.0;Urothelial cells: 153.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054646, HPA067421" Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Nucleoli" Cytosol "HPA054646: AB_2682555, HPA067421: AB_2685836" "unprognostic (2.08e-1)" "unprognostic (1.71e-3)" "unprognostic (7.50e-2)" "unprognostic (4.18e-2)" "unprognostic (1.65e-1)" "prognostic favorable (7.03e-4)" "unprognostic (3.43e-2)" "unprognostic (1.93e-1)" "unprognostic (1.76e-1)" "unprognostic (9.02e-2)" "unprognostic (1.70e-2)" "unprognostic (2.13e-1)" "prognostic favorable (8.43e-4)" "unprognostic (2.54e-1)" "unprognostic (2.60e-1)" "unprognostic (5.92e-2)" "unprognostic (1.11e-2)" 8.4 6.5 13.6 2.9 46.6 2.3 8.7 10.2 20.5 16.1 10.5 8.3 4.8 8.6 4.7 30.4 9.9 3.9 6.7 12.9 8.5 11.1 17.3 10.6 3.5 9.5 8.5 12.5 4.9 3.3 13.8 3.7 8.2 16.6 1.9 3.8 9.4 4.7 12.3 20.7 6.2 2.6 7.8 6.0 6.7 10.3 8.7 3.6 8.0 4.6 3.3 10.4 20.2 10.5 4.8 6.0 11.9 8.6 3.9 3.1 4.9 5.1 4.1 5.2 3.8 4.9 2.8 1.1 3.1 4.5 7.6 4.6 2.3 16.3 1.7 0.1 1.9 0.5 3.6 12.0 3.5 0.3 6.5 2.6 10.9 2.7 3.6 4.6 11.5 4.2 5.6 0.2 4.8 4.1 0.8 13.1 5.6 2.7 5.7 12.3 4.6 4.0 2.7 14.1 13.3 13.8 3.2 2.2 11.4 2.9 5.4 8.2 8.7 10.0 6.5 2.0 5.5 5.9 4.9 2.7 5.9 7.2 7.3 0.4 0.3 0.0 0.2 1.1 0.0 0.0 0.2 0.1 0.4 0.2 0.3 0.1 0.4 0.0 1.1 0.2 0.2 0.2 13.6 46.6 10.2 20.5 12.9 8.5 9.5 8.5 8.2 7.8 8.7 10.5 16.1 6.4 6.4 66.9 2.6 84.4 142.0 69.3 71.2 17.3 11.0 14.9 8.6 8.6 28.6 5.5 29.2 6.2 1.3 6.4 3.9 10.4 5.0 22.8 13.3 26.6 14.9 4.8 44.3 10.4 1.3 14.6 7.7 11.8 14.0 57.7 27.8 28.8 20.8 10.1 170.1 10.8 8.2 12.4 11.3 5.5 14.9 21.7 17.8 47.8 7.8 29.3 2.1 71.4 25.5 14.7 2.7 7.9 0.8 53.9 6.0 23.9 34.6 18.9 0.0 12.5 12.7 24.0 15.3 84.4 110.0 6.7 4.3 11.8 9.0 153.8 RGS13 ENSG00000127074 "Regulator of G protein signaling 13" O14921 1 192636138-192660311 "Predicted intracellular proteins" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "lymphoid tissue: 48.0" "Cell type enriched" "Detected in some" 16 "granulocytes: 520.0" "Cancer enhanced" "Detected in single" "stomach cancer: 0.6" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 39 "basophil: 6.8" "Lineage enriched" "Detected in single" 39 "granulocytes: 6.8" "Cell line enriched" "Detected in some" 20 "Daudi: 47.2" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA076656 Enhanced NA NA "Cluster 10: Basophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 60: Granulocytes - Receptor signaling" "HPA076656: " "unprognostic (1.99e-2)" "unprognostic (6.08e-3)" "unprognostic (3.25e-4)" "unprognostic (1.86e-1)" "unprognostic (2.31e-1)" "unprognostic (4.37e-5)" "unprognostic (1.93e-1)" "unprognostic (2.08e-3)" "unprognostic (2.04e-1)" "unprognostic (1.44e-1)" "unprognostic (7.39e-2)" "unprognostic (1.28e-1)" "unprognostic (8.65e-2)" "unprognostic (3.42e-1)" "unprognostic (2.35e-1)" "unprognostic (6.86e-2)" "unprognostic (1.96e-1)" 0.5 0.0 0.0 9.5 0.0 0.7 2.3 0.0 0.0 1.6 0.0 2.3 3.1 1.0 0.7 1.7 0.3 3.7 0.1 0.0 0.0 0.0 0.0 3.9 48.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 1.2 1.6 0.0 0.3 0.6 0.0 0.3 5.7 1.2 0.0 0.3 2.0 0.1 0.1 1.3 0.0 0.2 35.1 1.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.2 30.8 0.0 4.8 1.9 2.1 0.0 0.0 0.0 0.1 0.3 0.3 0.0 1.3 0.0 0.0 0.0 2.9 0.1 0.0 0.1 0.0 0.0 0.0 0.3 7.1 0.0 0.2 0.0 0.0 0.9 12.2 0.0 520.0 0.0 0.0 0.0 0.3 0.0 0.6 0.6 0.0 0.6 7.1 0.0 0.0 3.8 7.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.4 0.0 3.9 1.7 0.2 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 1.3 0.0 7.9 0.5 1.6 0.1 RGS9BP "FLJ45744, PERRS, R9AP" ENSG00000186326 "Regulator of G protein signaling 9 binding protein" Q6ZS82 19 32675848-32678300 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Sensory transduction, Vision" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "choroid plexus: 28.9;retina: 17.4;skeletal muscle: 9.0" "Group enriched" "Detected in some" 5 "Bipolar cells: 29.0;Cone photoreceptor cells: 56.3;Rod photoreceptor cells: 75.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 6.3;HMC-1: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA049791 Enhanced Approved "Plasma membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 36: HEL - Hemostasis" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane" "HPA049791: AB_2680884" "unprognostic (2.82e-2)" "unprognostic (6.99e-3)" "unprognostic (2.44e-3)" "unprognostic (1.20e-7)" "unprognostic (1.49e-1)" "unprognostic (1.21e-2)" "unprognostic (1.17e-2)" "unprognostic (1.32e-1)" "unprognostic (2.80e-1)" "unprognostic (6.71e-2)" "unprognostic (6.74e-2)" "unprognostic (3.89e-2)" "unprognostic (1.63e-3)" "unprognostic (2.29e-1)" "unprognostic (8.22e-2)" "unprognostic (5.23e-2)" "unprognostic (5.34e-2)" 0.0 0.1 0.8 0.0 0.7 0.0 0.0 0.8 0.8 0.0 28.9 0.1 0.0 0.0 0.1 0.4 0.0 0.0 1.3 3.3 0.9 0.3 0.0 0.3 0.0 1.1 1.4 0.0 0.0 0.2 0.2 0.0 0.9 0.2 0.0 17.4 0.1 0.1 9.0 0.1 0.0 0.0 0.5 0.0 0.1 0.4 1.5 0.1 0.0 3.2 0.0 0.4 0.0 0.7 0.1 0.1 0.0 0.5 0.3 0.1 0.3 0.0 0.3 0.2 0.1 0.0 0.1 0.1 0.3 0.0 0.3 0.0 1.0 0.0 0.0 0.2 0.1 6.3 0.1 0.0 0.1 0.1 1.6 0.0 0.3 0.0 0.2 0.1 0.0 0.0 0.4 0.8 0.1 0.2 0.0 1.0 0.0 0.0 1.1 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.6 0.3 0.0 0.2 0.3 0.1 0.1 0.3 0.4 0.0 0.1 0.3 0.4 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.7 0.8 0.8 3.3 0.9 1.1 1.4 0.9 0.5 1.5 0.7 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 29.0 0.4 0.4 4.6 0.0 0.0 1.8 56.3 0.3 0.6 0.5 0.0 0.0 5.1 0.2 0.1 0.7 0.0 0.8 0.0 0.0 0.2 0.2 0.0 0.4 0.0 1.8 0.7 0.0 0.2 1.7 0.0 0.0 0.0 0.3 0.0 1.5 0.0 0.1 0.0 0.0 0.0 9.4 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.2 0.4 0.9 0.0 75.4 0.0 0.4 0.2 0.5 0.4 0.0 0.0 0.0 0.1 1.1 0.4 0.0 RHBDF2 "FLJ22341, iRhom2, RHBDL5, RHBDL6, TOC, TOCG" ENSG00000129667 "Rhomboid 5 homolog 2" Q6PJF5 17 76470891-76501790 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Growth factor binding" "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 58.4;Kupffer cells: 57.3;NK-cells: 64.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 75.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA018080 Uncertain NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 57: B-cells - Immune response" "HPA018080: AB_2178634" "unprognostic (1.19e-1)" "unprognostic (8.71e-2)" "unprognostic (1.59e-2)" "unprognostic (5.11e-3)" "unprognostic (4.33e-2)" "unprognostic (1.63e-1)" "unprognostic (2.63e-3)" "unprognostic (9.79e-3)" "unprognostic (2.55e-1)" "unprognostic (1.72e-1)" "unprognostic (4.49e-2)" "unprognostic (1.38e-1)" "prognostic unfavorable (3.96e-11)" "unprognostic (5.24e-2)" "unprognostic (2.14e-2)" "unprognostic (1.61e-2)" "unprognostic (1.14e-1)" 18.3 10.1 9.4 31.2 8.6 29.7 13.6 11.7 11.0 8.8 11.6 9.0 6.5 7.4 1.6 23.9 10.1 10.3 10.3 9.7 12.1 10.9 6.3 24.8 27.6 26.6 17.2 8.0 19.5 3.1 5.3 9.7 22.4 9.1 4.4 2.9 11.6 2.6 13.5 29.1 26.6 6.4 20.9 42.2 10.5 3.0 30.0 6.5 12.3 3.1 21.3 11.0 15.7 28.8 38.3 43.3 1.3 10.7 0.4 1.1 30.1 8.6 26.9 6.7 9.1 13.3 45.0 41.5 28.6 10.9 39.0 29.9 7.3 40.8 6.2 7.1 13.6 2.8 3.5 21.8 25.6 1.8 5.9 4.5 20.2 18.1 20.7 15.4 20.3 5.9 4.3 18.3 4.6 30.7 4.3 4.7 6.7 25.7 26.1 10.3 0.4 75.3 17.8 14.0 9.2 12.6 9.9 28.7 38.7 8.5 24.7 11.4 32.4 0.6 14.4 0.7 11.0 44.3 22.6 33.7 24.3 11.2 27.1 6.3 13.4 4.3 8.0 13.1 5.5 12.7 2.1 5.8 6.5 7.4 1.5 3.6 10.2 4.9 12.2 10.0 1.1 8.8 9.4 8.6 11.7 11.0 9.7 12.1 26.6 17.2 22.4 20.9 30.0 28.8 22.3 6.4 6.9 2.3 58.4 17.6 15.3 35.0 8.0 4.2 4.7 5.5 3.3 18.6 19.2 3.7 2.1 1.0 47.1 2.0 0.0 21.3 0.5 4.2 0.8 15.3 1.8 1.3 0.6 9.8 2.2 4.7 7.7 6.6 0.0 15.4 7.9 3.4 37.6 0.0 0.5 4.1 6.1 57.3 42.7 0.7 0.9 48.8 10.6 38.4 40.1 1.1 64.9 1.0 0.1 14.2 4.8 0.4 36.5 20.4 1.9 1.8 16.2 1.4 6.6 3.6 3.2 0.7 7.1 9.9 29.3 1.6 22.3 2.8 7.8 20.4 RIMS1 "CORD7, KIAA0340, RAB3IP2, RIM, RIM1" ENSG00000079841 "Regulating synaptic membrane exocytosis 1" Q86UR5 6 71886703-72403143 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Exocytosis, Neurotransmitter transport, Sensory transduction, Transport, Vision" "Cone-rod dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 49 "brain: 365.0" "Group enriched" "Detected in many" 4 "Excitatory neurons: 653.2;Inhibitory neurons: 572.7;Oligodendrocyte precursor cells: 323.2" "Cancer enhanced" "Detected in single" "prostate cancer: 0.7" "Region enriched" "Detected in many" 16 "cerebellum: 365.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 5.2;EFO-21: 8.8;LHCN-M2: 10.0;RPTEC TERT1: 15.0;SH-SY5Y: 10.7;TIME: 5.4;U-138 MG: 5.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 352.9" HPA076565 Enhanced NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA076565: " "unprognostic (1.34e-3)" "unprognostic (3.47e-1)" "unprognostic (1.48e-1)" "unprognostic (1.63e-3)" "unprognostic (6.62e-2)" "unprognostic (1.16e-1)" "unprognostic (1.73e-2)" "unprognostic (8.57e-2)" "unprognostic (2.85e-1)" "unprognostic (7.76e-4)" "unprognostic (2.42e-2)" "unprognostic (2.29e-1)" "unprognostic (7.91e-2)" "unprognostic (2.76e-1)" "unprognostic (5.74e-2)" "unprognostic (1.07e-2)" 0.2 1.2 5.5 0.8 14.1 0.0 0.5 365.0 22.5 0.3 0.0 0.3 0.7 0.2 0.0 2.1 0.0 3.9 0.1 16.3 8.4 0.0 0.0 0.2 0.0 0.3 9.0 0.0 0.4 1.6 2.4 0.0 20.8 3.0 0.1 7.4 1.1 0.3 0.2 0.2 0.4 0.7 0.0 0.0 1.4 4.1 5.4 0.0 0.0 0.9 0.0 0.1 0.0 13.2 0.0 0.0 1.0 0.0 0.0 0.5 0.0 0.2 1.4 0.0 0.2 0.0 0.0 5.2 8.8 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.4 1.6 0.0 0.0 0.0 0.0 10.0 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.0 0.5 15.0 0.0 0.4 10.7 0.0 0.0 0.0 0.3 0.7 0.0 5.4 5.1 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 14.1 365.0 22.5 16.3 8.4 0.3 9.0 20.8 0.0 5.4 13.2 0.2 0.0 0.5 120.2 0.0 0.0 0.2 2.1 0.0 69.1 3.0 3.2 1.4 0.0 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 15.2 0.0 0.9 2.5 0.0 0.0 653.2 0.8 0.0 1.8 0.0 0.0 1.3 0.3 3.6 0.0 0.0 62.2 572.7 0.0 2.0 0.0 0.0 10.2 0.3 0.3 3.6 16.9 0.0 109.7 0.0 323.2 76.5 0.5 0.0 1.5 0.0 1.0 0.0 0.4 3.6 9.9 0.0 1.3 2.7 21.3 13.6 0.0 0.1 0.0 0.1 0.3 0.0 0.5 RNF167 DKFZP566H073 ENSG00000108523 "Ring finger protein 167" Q9H6Y7 17 4940008-4945222 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049810 Approved Approved "Vesicles,Mitotic spindle,Centriolar satellite,Cytosol" Yes NA "Cluster 5: Granulocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Vesicles, Cytosol" "Mitotic spindle, Centriolar satellite" "HPA049810: AB_2680894" "unprognostic (1.13e-1)" "unprognostic (5.12e-2)" "unprognostic (2.29e-3)" "unprognostic (1.63e-2)" "unprognostic (3.43e-2)" "unprognostic (7.32e-2)" "unprognostic (2.18e-1)" "unprognostic (6.77e-2)" "unprognostic (7.46e-2)" "unprognostic (2.07e-2)" "prognostic favorable (2.03e-6)" "unprognostic (2.16e-1)" "prognostic favorable (4.47e-4)" "unprognostic (7.62e-2)" "unprognostic (1.93e-1)" "unprognostic (3.26e-1)" "unprognostic (1.12e-1)" 75.0 110.6 141.9 53.0 146.7 69.0 73.1 146.4 179.9 93.2 138.6 111.5 66.6 94.9 76.4 122.1 84.3 45.3 131.8 141.5 146.4 106.7 184.2 77.5 64.5 146.3 145.4 87.4 115.1 105.8 96.8 50.7 146.3 95.0 65.7 98.1 92.5 70.5 152.9 127.8 100.5 52.8 142.4 113.8 111.8 110.6 150.3 98.1 93.4 94.2 71.6 106.7 90.4 153.3 102.6 143.1 61.1 73.7 132.8 68.7 92.7 63.4 76.1 119.7 93.4 96.2 43.3 71.5 120.3 93.5 63.9 147.5 103.2 114.8 86.1 74.5 166.1 121.9 164.4 94.9 100.6 59.0 245.0 79.6 176.5 129.8 116.2 74.6 77.2 101.0 49.9 237.5 96.2 66.3 92.8 70.6 75.4 102.0 86.8 62.8 61.9 91.5 137.3 77.4 49.2 61.1 56.0 92.9 81.9 83.1 87.3 55.9 49.5 76.6 48.3 66.8 119.3 79.5 88.0 23.7 98.4 80.6 77.9 108.4 88.8 236.9 195.3 94.0 153.4 100.4 148.0 195.7 73.9 98.7 103.2 152.2 219.8 118.8 117.7 75.9 153.0 177.0 141.9 146.7 146.4 179.9 141.5 146.4 146.3 145.4 146.3 142.4 150.3 153.3 36.9 0.0 3.9 12.4 54.3 68.6 44.4 65.8 51.8 43.2 56.6 44.7 15.8 77.2 38.9 49.7 20.9 120.1 64.7 65.2 56.7 78.5 59.6 29.8 25.1 36.4 31.8 60.6 11.3 66.7 139.7 36.3 36.2 32.2 14.0 26.3 45.7 95.1 58.4 18.5 11.2 45.7 65.1 41.3 43.6 86.5 48.7 36.1 39.2 6.5 53.1 46.9 114.4 10.1 17.9 60.7 44.9 53.8 59.1 32.6 108.2 64.0 31.1 32.3 39.5 28.4 35.1 127.1 106.7 61.4 83.3 125.2 82.5 37.2 59.6 48.0 RNF227 LINC02581 ENSG00000179859 "Ring finger protein 227" A6NIN4 17 7913339-7916289 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in all" 5 "skin 1: 64.3" "Cell type enhanced" "Detected in some" "Adipocytes: 3.9;Breast glandular cells: 3.9;Breast myoepithelial cells: 4.1;Endometrial ciliated cells: 5.0;Endometrial stromal cells: 8.9;Glandular and luminal cells: 5.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 17.5" "Lineage enriched" "Detected in all" 5 "granulocytes: 17.5" "Cell line enhanced" "Detected in many" "SiHa: 14.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 61: Skin - Cornification" "Cluster 20: HeLa - Mitochondria" "Cluster 7: Non-specific - Mitochondria" "unprognostic (8.85e-3)" "prognostic favorable (8.89e-5)" "unprognostic (1.50e-2)" "unprognostic (4.88e-2)" "unprognostic (3.72e-3)" "unprognostic (1.44e-2)" "unprognostic (2.02e-5)" "unprognostic (9.48e-2)" "unprognostic (9.22e-3)" "unprognostic (2.94e-2)" "unprognostic (3.11e-2)" "unprognostic (3.31e-2)" "unprognostic (7.96e-2)" "unprognostic (1.43e-2)" "unprognostic (1.18e-1)" "unprognostic (3.30e-2)" "unprognostic (1.80e-2)" 5.8 3.2 5.3 1.9 5.5 1.7 4.8 7.0 6.4 3.4 4.1 2.9 3.5 6.2 4.6 4.5 5.0 1.9 1.8 5.5 5.5 2.6 1.1 3.5 2.5 4.9 5.0 5.1 3.5 4.7 3.9 2.2 4.7 2.9 2.0 11.9 3.1 2.1 1.4 64.3 2.9 2.6 4.7 3.0 2.5 3.3 5.4 2.3 1.7 1.6 2.7 2.2 4.1 5.2 7.0 1.4 2.6 2.6 2.0 1.8 2.2 6.5 2.6 1.8 2.0 4.1 2.0 1.3 3.8 2.6 1.6 5.0 1.5 3.3 3.2 0.8 1.7 1.8 5.1 0.3 3.8 3.8 3.3 2.3 9.4 2.9 3.1 0.9 0.4 6.9 2.1 1.3 4.1 0.8 5.1 4.8 1.8 2.1 1.0 2.4 6.4 1.5 2.6 0.9 1.1 3.6 14.1 0.6 2.8 0.8 1.7 2.8 0.4 0.1 3.6 3.1 1.3 1.8 0.6 1.9 3.8 4.2 4.9 17.5 1.3 0.4 1.7 0.9 2.2 1.9 1.9 2.2 2.0 1.3 3.5 2.4 0.8 2.7 0.8 1.3 1.5 1.5 5.3 5.5 7.0 6.4 5.5 5.5 4.9 5.0 4.7 4.7 5.4 5.2 3.9 3.2 2.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 3.9 4.1 0.0 0.0 0.0 0.0 0.0 1.3 2.7 0.0 1.9 1.0 0.0 5.0 8.9 1.1 0.0 0.0 0.0 0.2 0.5 1.9 0.0 5.5 0.0 2.2 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.4 0.0 0.0 0.8 2.2 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.7 0.7 2.2 0.0 0.0 RNH1 "RAI, RNH" ENSG00000023191 "Ribonuclease/angiogenin inhibitor 1" P13489 11 494512-507300 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 262.3;monocytes: 299.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039223, HPA040781" Enhanced Enhanced Nucleoplasm,Cytosol NA NA 22000000 "Cluster 7: Monocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Cytosol" "HPA039223: AB_10795581, HPA040781: AB_10796227" "unprognostic (1.87e-1)" "unprognostic (2.44e-1)" "unprognostic (1.38e-1)" "unprognostic (1.59e-3)" "unprognostic (2.48e-3)" "unprognostic (6.09e-2)" "unprognostic (4.82e-3)" "unprognostic (1.35e-1)" "unprognostic (1.96e-1)" "unprognostic (2.20e-1)" "unprognostic (1.55e-1)" "unprognostic (2.44e-1)" "prognostic favorable (2.14e-5)" "unprognostic (3.35e-1)" "unprognostic (1.66e-1)" "unprognostic (4.78e-2)" "unprognostic (4.35e-2)" 163.5 137.2 27.3 29.0 41.8 46.3 133.7 42.4 33.9 156.4 28.9 123.0 27.1 140.8 10.0 215.0 119.5 29.7 198.0 26.3 32.5 118.6 111.9 146.7 30.8 48.6 39.7 119.1 89.5 25.6 80.6 27.3 38.2 100.9 8.8 5.6 112.5 31.0 145.9 257.4 91.1 25.3 35.3 113.3 101.1 90.1 38.3 15.6 106.6 21.8 13.9 144.5 160.3 49.4 86.5 123.9 13.2 39.8 66.3 93.8 43.9 70.6 51.3 68.9 58.3 61.9 92.9 41.8 54.3 175.1 41.9 72.7 20.6 76.5 10.4 51.3 104.9 28.2 28.5 65.7 243.3 39.8 90.0 77.1 108.2 40.2 46.7 29.2 47.9 27.7 36.2 71.3 37.7 86.6 30.5 78.4 19.8 45.3 112.6 37.7 22.3 55.8 40.7 34.6 35.7 23.2 41.8 59.1 73.7 7.4 44.6 122.2 77.3 109.3 32.8 39.8 49.5 44.9 53.0 32.2 117.5 81.9 74.3 37.6 246.2 57.3 51.1 298.9 59.9 63.0 55.3 51.1 262.3 48.4 49.8 45.1 17.1 54.2 299.1 71.7 58.4 236.5 27.3 41.8 42.4 33.9 26.3 32.5 48.6 39.7 38.2 35.3 38.3 49.4 156.0 112.2 83.5 18.9 92.3 202.1 239.0 265.0 89.4 102.4 82.0 105.5 83.3 88.6 138.6 79.1 110.5 222.2 85.3 126.6 225.0 188.8 105.1 72.8 132.4 136.1 57.4 59.7 10.9 164.4 217.4 194.9 64.2 82.8 140.2 93.8 101.7 68.6 374.0 168.2 14.5 115.6 148.5 191.8 323.0 42.7 211.6 230.3 193.9 12.2 334.2 144.6 79.3 10.1 70.8 171.6 120.5 179.8 101.7 161.0 139.4 242.3 97.9 146.4 177.5 99.1 178.0 153.4 157.8 140.0 260.0 305.5 96.5 199.7 114.4 217.4 ROBO2 KIAA1568 ENSG00000185008 "Roundabout guidance receptor 2" Q9HCK4 3 75906695-77649964 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Chemotaxis, Differentiation, Neurogenesis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.7;retina: 15.4" "Group enriched" "Detected in many" 24 "Excitatory neurons: 3438.7;Inhibitory neurons: 4706.0" "Cancer enhanced" "Detected in many" "glioma: 3.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "BJ hTERT+: 29.8;HEL: 83.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013371, HPA013975" Approved Approved "Nucleoplasm,Plasma membrane,Centriolar satellite" NA NA 1900000 "Cluster 58: Brain - Synaptic function" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Nucleoplasm, Centriolar satellite" "HPA013371: AB_1856391, HPA013975: " "unprognostic (1.14e-3)" "unprognostic (1.93e-1)" "unprognostic (1.46e-2)" "unprognostic (7.25e-3)" "unprognostic (1.82e-2)" "unprognostic (5.93e-3)" "unprognostic (3.87e-1)" "unprognostic (2.83e-3)" "unprognostic (4.07e-2)" "unprognostic (4.23e-1)" "unprognostic (2.90e-2)" "unprognostic (1.76e-1)" "unprognostic (3.08e-4)" "unprognostic (2.06e-1)" "unprognostic (1.07e-1)" "unprognostic (1.99e-2)" "unprognostic (9.65e-3)" 0.7 2.4 10.1 0.5 13.6 0.0 0.6 0.0 14.2 2.4 0.0 0.8 0.5 2.1 0.4 4.8 0.1 2.3 0.6 10.4 1.7 1.8 1.2 10.0 1.5 14.8 13.1 7.0 1.6 2.8 1.5 5.2 14.3 1.2 0.4 15.4 1.6 5.7 0.1 2.3 0.7 1.4 16.7 2.9 0.7 3.7 4.9 9.3 0.1 0.4 2.2 1.2 1.7 8.1 0.0 0.0 2.2 0.0 7.5 8.1 0.1 0.3 29.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.9 0.0 0.0 0.0 9.8 83.9 1.0 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.5 0.0 5.1 9.1 0.0 0.0 1.1 5.1 12.2 0.0 0.0 0.0 0.3 0.4 0.0 0.1 0.0 0.5 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.1 13.6 0.0 14.2 10.4 1.7 14.8 13.1 14.3 16.7 4.9 8.1 0.7 0.0 0.5 164.6 0.0 1.8 2.0 0.4 19.4 30.8 0.2 1.0 2.4 1.5 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 12.2 1.0 1.7 1.1 0.0 0.0 3438.7 0.0 0.1 10.6 0.0 3.2 0.0 2.3 3.3 0.7 0.1 52.2 4706.0 3.0 0.0 0.0 2.8 3.4 3.1 0.1 0.0 54.4 0.0 2.0 0.0 63.3 52.4 0.2 0.0 6.0 0.0 0.8 0.3 0.1 0.1 5.6 0.0 0.1 0.9 2.9 1.1 15.7 1.1 0.1 0.2 40.5 0.5 0.2 RPA3 REPA3 ENSG00000106399 "Replication protein A3" P35244 7 7636518-7718607 "Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, DNA replication" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 428.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005708 Approved NA NA 17000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "HPA005708: AB_1856411" "unprognostic (2.06e-2)" "unprognostic (2.27e-2)" "unprognostic (2.40e-1)" "unprognostic (1.63e-1)" "unprognostic (7.20e-3)" "unprognostic (3.75e-2)" "prognostic unfavorable (5.16e-5)" "unprognostic (5.31e-2)" "unprognostic (2.65e-2)" "unprognostic (1.17e-1)" "unprognostic (2.42e-1)" "unprognostic (1.20e-1)" "unprognostic (7.41e-2)" "unprognostic (1.08e-1)" "unprognostic (7.24e-2)" "unprognostic (2.61e-1)" "unprognostic (5.83e-2)" 16.4 25.7 12.4 22.9 14.4 46.2 24.4 14.3 19.7 12.5 19.9 25.2 15.8 10.5 37.1 19.6 25.5 10.6 20.5 12.3 15.7 35.7 40.5 14.6 37.9 13.9 13.1 12.7 15.4 46.4 27.2 16.4 15.3 11.5 19.9 34.1 14.5 13.6 18.7 13.3 18.4 9.6 14.7 23.4 20.8 22.5 13.8 51.8 19.3 12.5 35.6 16.3 12.5 15.7 174.1 95.9 94.8 102.3 35.2 31.9 67.2 47.6 44.3 73.0 116.2 92.3 153.1 88.4 45.2 36.0 235.9 129.2 64.5 85.9 106.4 41.1 112.0 48.1 111.9 189.2 15.3 102.5 38.9 23.4 29.9 85.0 59.6 36.0 41.9 168.6 119.5 132.6 70.8 257.0 83.9 198.1 149.9 104.9 125.1 98.3 154.9 141.6 52.3 84.0 70.5 86.8 88.2 91.6 51.0 137.9 122.0 107.4 19.3 60.5 169.1 99.8 113.7 102.7 199.9 167.7 89.7 119.3 118.5 17.9 25.3 27.2 34.1 40.8 40.9 75.4 55.7 44.0 31.9 76.9 45.6 46.3 22.2 29.7 49.0 61.6 68.5 35.7 12.4 14.4 14.3 19.7 12.3 15.7 13.9 13.1 15.3 14.7 13.8 15.7 35.6 38.5 39.5 2.9 93.2 40.5 65.0 160.8 41.5 24.1 54.7 73.9 39.0 60.1 89.5 71.7 10.4 152.2 53.2 61.9 273.9 84.8 96.9 144.8 34.9 35.7 25.3 218.2 5.2 105.4 257.5 43.3 39.8 61.8 53.9 43.2 36.0 154.5 131.4 16.8 5.6 75.1 83.4 48.7 54.2 24.4 39.1 49.9 56.9 1.9 68.2 63.7 56.7 6.0 5.8 64.1 70.4 24.5 75.8 25.9 74.3 428.6 269.9 44.7 6.6 34.7 46.9 112.7 65.9 59.6 34.4 66.2 68.7 46.1 90.5 66.2 RREB1 HNT ENSG00000124782 "Ras responsive element binding protein 1" Q92766 6 7107597-7251980 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA001756, HPA034843" Approved Supported "Nucleoli fibrillar center,Nuclear speckles" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 1: K-562 - Erythropoiesis" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nuclear speckles" "Nucleoli fibrillar center" "HPA001756: AB_1856477, HPA034843: AB_2674357" "unprognostic (1.69e-1)" "unprognostic (3.16e-2)" "unprognostic (2.93e-1)" "unprognostic (5.05e-2)" "unprognostic (7.38e-2)" "unprognostic (1.23e-3)" "unprognostic (2.53e-1)" "unprognostic (1.32e-2)" "unprognostic (2.45e-2)" "unprognostic (6.51e-2)" "unprognostic (3.31e-2)" "unprognostic (1.16e-1)" "prognostic favorable (1.41e-4)" "unprognostic (1.21e-2)" "unprognostic (1.60e-1)" "unprognostic (9.54e-2)" "unprognostic (2.92e-1)" 10.9 12.1 4.3 7.8 3.6 31.6 10.8 4.4 2.2 10.2 12.5 10.8 11.9 7.8 5.6 26.2 8.7 6.4 8.3 2.7 4.2 8.2 18.3 9.1 6.5 9.1 6.6 9.8 18.1 12.2 6.3 8.1 6.5 8.1 9.8 5.7 15.0 6.2 16.6 16.2 13.1 6.2 5.4 10.7 10.7 11.6 7.6 9.2 12.0 7.9 7.9 7.9 14.2 5.5 13.1 12.3 10.3 11.9 9.5 6.3 40.1 5.2 7.3 6.2 7.6 20.3 10.0 6.6 10.9 9.9 6.9 9.3 14.7 16.5 5.9 9.2 11.3 24.8 9.6 23.5 13.1 15.0 18.5 10.5 12.7 9.3 13.8 4.2 7.5 15.2 44.6 0.1 6.5 16.5 8.8 35.2 4.9 10.6 10.0 13.1 12.4 10.4 9.0 25.1 2.8 2.6 12.4 16.0 11.1 15.3 12.3 31.0 13.0 11.4 7.1 8.8 6.4 4.1 4.7 9.0 3.3 11.4 9.3 5.5 2.7 6.6 1.5 2.1 1.3 2.2 1.0 1.0 1.7 1.0 1.6 1.3 2.0 3.3 2.4 5.7 0.5 1.7 4.3 3.6 4.4 2.2 2.7 4.2 9.1 6.6 6.5 5.4 7.6 5.5 39.3 25.6 28.7 44.4 19.0 31.5 22.4 30.1 27.9 0.9 27.0 16.9 24.2 31.5 31.4 36.8 70.9 25.8 31.9 62.7 7.9 14.7 46.2 35.5 24.7 22.5 31.8 31.1 3.9 16.3 32.8 16.3 30.1 63.0 10.1 20.7 30.7 70.4 33.4 0.0 0.7 35.7 14.2 66.1 54.9 9.0 19.9 42.1 23.2 78.7 32.6 9.5 13.4 2.0 0.9 22.3 36.3 19.2 27.7 37.1 34.5 16.8 23.9 27.5 52.6 25.5 15.2 13.7 17.4 48.9 34.7 45.8 15.7 27.4 45.0 54.3 RRM2 "C2orf48, FLJ25102" ENSG00000171848 "Ribonucleotide reductase regulatory subunit M2" P31350 2 10120698-10211725 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "DNA replication" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 44.2;esophagus: 18.4;intestine: 19.7;lymphoid tissue: 58.1" "Group enriched" "Detected in many" 4 "Erythroid cells: 214.0;Extravillous trophoblasts: 254.1;Plasma cells: 248.0" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056994 Enhanced Supported Cytosol Yes Yes 13000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA056994: AB_2683304" "unprognostic (2.10e-2)" "unprognostic (1.62e-1)" "unprognostic (6.40e-3)" "unprognostic (4.42e-3)" "unprognostic (5.70e-2)" "unprognostic (1.69e-1)" "prognostic unfavorable (1.39e-5)" "unprognostic (1.04e-3)" "unprognostic (6.67e-3)" "unprognostic (4.53e-2)" "prognostic unfavorable (1.62e-4)" "unprognostic (5.11e-3)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.05e-2)" "unprognostic (2.24e-1)" "unprognostic (1.38e-1)" "unprognostic (2.09e-2)" 1.5 1.3 0.3 12.4 0.3 44.2 2.9 0.5 0.4 3.0 1.9 14.2 9.4 2.2 0.7 18.4 0.8 1.1 0.5 0.3 0.3 0.9 3.2 2.4 35.5 0.4 0.4 0.3 1.1 0.3 0.2 4.6 0.4 0.9 19.7 0.2 2.1 0.5 0.1 3.7 7.5 6.1 0.3 11.1 6.0 2.9 0.8 58.1 0.9 0.1 37.6 6.0 4.6 0.5 110.2 25.0 127.1 49.9 7.4 22.5 116.8 209.2 128.6 170.2 187.9 70.8 59.1 114.4 9.5 88.6 151.1 55.0 188.0 136.6 198.0 210.7 41.8 146.3 52.1 105.1 0.8 146.7 87.4 8.1 3.4 234.6 16.2 27.7 103.3 110.4 63.4 328.6 214.3 57.1 167.3 90.9 83.0 133.3 103.6 87.6 187.0 67.8 87.1 62.7 67.7 56.2 198.0 116.6 17.3 51.8 69.2 31.4 57.6 93.1 125.1 66.9 289.6 212.1 184.9 195.9 51.0 134.4 107.7 0.3 0.1 0.1 1.2 0.0 0.0 0.1 0.3 0.8 0.1 0.1 0.1 0.4 0.4 0.8 0.0 0.1 0.2 0.2 0.3 0.3 0.5 0.4 0.3 0.3 0.4 0.4 0.4 0.3 0.8 0.5 0.2 3.2 1.5 0.0 25.0 10.5 3.0 9.2 1.2 0.0 3.9 4.4 1.4 1.5 2.3 0.0 0.0 42.3 5.6 12.9 1.9 1.2 3.9 2.2 3.5 4.2 0.0 214.0 0.1 0.0 254.1 11.2 11.7 3.6 5.7 12.2 3.9 3.7 47.9 0.0 0.0 26.9 2.0 7.2 8.8 6.8 0.3 5.0 0.0 1.0 0.0 0.0 7.2 0.0 0.0 0.5 0.3 0.4 248.0 1.5 2.4 2.1 4.6 0.0 0.0 0.2 14.6 22.9 34.0 51.5 1.6 48.7 11.9 1.2 36.7 5.6 RTCB "C22orf28, FAAP, HSPC117" ENSG00000100220 "RNA 2',3'-cyclic phosphate and 5'-OH ligase" Q9Y3I0 22 32387582-32412248 "Enzymes, Predicted intracellular proteins" "tRNA processing" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000535, HPA001103" Supported Supported Nucleoplasm,Vesicles,Cytosol NA NA 73000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "Vesicles, Cytosol" "HPA000535: AB_2666021, HPA001103: AB_1078351" "unprognostic (1.84e-1)" "unprognostic (6.48e-2)" "unprognostic (1.07e-2)" "unprognostic (2.71e-3)" "unprognostic (7.21e-3)" "unprognostic (1.43e-2)" "unprognostic (1.75e-3)" "unprognostic (1.49e-1)" "unprognostic (3.01e-1)" "unprognostic (1.52e-1)" "unprognostic (2.40e-2)" "unprognostic (5.07e-2)" "prognostic favorable (4.25e-5)" "unprognostic (6.91e-2)" "unprognostic (5.35e-2)" "unprognostic (2.05e-1)" "unprognostic (1.55e-1)" 43.5 44.5 33.3 39.0 36.0 31.4 51.2 37.5 40.8 37.7 35.6 56.1 93.9 43.9 43.7 49.4 46.5 32.6 45.8 33.5 38.1 75.9 75.2 36.3 45.6 36.7 37.0 45.6 45.8 73.0 39.8 45.5 39.1 45.9 73.8 44.1 47.2 47.4 71.1 76.9 79.1 56.0 38.3 43.7 48.4 32.0 36.3 72.9 41.5 63.6 87.9 53.9 39.2 40.2 116.1 101.9 125.0 94.3 106.8 79.1 99.3 98.8 118.5 154.6 145.9 133.2 45.9 28.5 64.6 116.1 95.2 76.7 144.7 143.5 198.6 144.3 144.8 81.4 83.0 122.1 73.4 192.4 71.2 78.3 93.7 153.3 147.8 85.1 141.3 78.5 98.2 78.7 114.3 96.4 82.5 66.4 71.7 133.4 91.7 126.0 134.7 147.1 106.0 99.0 128.3 71.1 107.2 68.5 129.2 130.6 75.5 73.8 107.3 84.8 124.8 74.7 96.5 54.4 46.6 102.1 87.8 85.6 113.4 112.5 135.3 89.2 93.0 151.3 104.4 143.5 96.6 97.4 161.4 150.4 114.8 99.1 13.2 125.7 118.7 90.4 131.7 156.3 33.3 36.0 37.5 40.8 33.5 38.1 36.7 37.0 39.1 38.3 36.3 40.2 32.0 32.1 33.4 15.3 40.3 60.5 54.9 84.9 47.8 51.6 35.4 27.6 35.8 47.1 60.6 35.0 20.9 112.6 43.0 74.8 66.5 108.4 4.8 46.3 28.6 45.4 46.7 36.4 22.4 95.6 87.9 35.8 45.9 53.8 42.6 50.5 41.0 58.3 85.4 52.2 19.6 62.2 116.0 47.4 45.9 10.8 35.1 43.2 30.2 25.3 80.0 66.9 34.0 28.6 35.1 106.5 62.1 47.8 36.0 64.3 178.2 146.9 48.2 56.9 26.3 35.4 43.0 67.0 65.1 52.7 76.0 97.8 34.1 59.3 61.3 73.8 RTN4R NOGOR ENSG00000040608 "Reticulon 4 receptor" Q9BZR6 22 20241415-20283246 "Disease related genes, Human disease related genes, Predicted membrane proteins" Receptor "Disease variant, Schizophrenia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.3;liver: 12.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 12.1;Excitatory neurons: 14.1;Muller glia cells: 11.3" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 10 "amygdala: 8.0;basal ganglia: 20.0;cerebellum: 20.9;cerebral cortex: 24.3;hippocampal formation: 12.7" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 10.8" "Lineage enriched" "Detected in many" 9 "T-cells: 10.8" "Cell line enhanced" "Detected in many" "NB-4: 38.2;REH: 53.9;SCLC-21H: 31.3;SK-MEL-30: 25.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB012443 Supported "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA 1900000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane, Focal adhesion sites" "Actin filaments" "CAB012443: " "unprognostic (1.28e-1)" "unprognostic (1.28e-2)" "unprognostic (8.29e-2)" "unprognostic (6.58e-2)" "unprognostic (3.49e-1)" "prognostic unfavorable (7.73e-4)" "unprognostic (2.19e-1)" "unprognostic (1.56e-1)" "unprognostic (3.44e-1)" "unprognostic (8.90e-3)" "unprognostic (1.21e-2)" "unprognostic (9.89e-2)" "unprognostic (1.80e-2)" "unprognostic (1.34e-2)" "unprognostic (1.30e-1)" "unprognostic (5.02e-2)" "unprognostic (3.07e-1)" 1.6 2.6 8.0 0.5 20.0 0.6 1.0 20.9 24.3 3.6 0.0 1.6 2.2 5.1 0.0 3.5 1.9 0.1 2.7 12.7 0.0 2.1 12.8 2.2 0.4 0.5 0.0 2.4 3.7 0.4 4.9 0.4 0.3 1.5 0.1 0.6 2.0 0.4 0.6 7.9 2.1 0.2 0.0 8.5 1.8 1.9 0.4 0.8 3.5 0.2 0.2 0.5 2.8 1.8 7.9 3.8 2.3 5.5 0.0 0.0 1.2 0.8 0.0 0.6 0.3 6.0 2.2 0.4 2.5 0.1 3.7 12.8 1.4 3.2 0.0 0.2 13.4 0.1 3.2 0.9 1.3 0.3 0.4 0.0 4.1 0.0 0.3 0.0 0.0 3.7 0.4 0.3 0.0 11.0 4.1 38.2 8.7 2.3 6.7 53.9 0.0 0.4 0.5 3.3 31.3 5.0 3.7 2.7 25.9 0.5 3.1 1.1 0.0 0.5 14.2 0.1 0.2 0.1 1.0 0.9 0.4 7.8 0.1 0.0 0.0 0.0 4.6 0.0 10.8 0.0 4.0 4.6 0.2 0.1 2.4 5.1 0.0 0.8 0.0 1.2 3.0 1.7 8.0 20.0 20.9 24.3 12.7 0.0 0.5 0.0 0.3 0.0 0.4 1.8 1.4 3.2 0.0 7.5 0.2 5.1 4.0 1.6 1.8 12.1 2.9 2.4 2.2 0.0 0.6 0.0 4.2 0.2 1.9 3.0 0.0 2.9 2.0 1.2 4.8 2.0 0.0 0.4 14.1 4.3 7.6 1.6 0.0 1.6 0.0 0.4 1.1 3.0 1.3 6.7 2.6 2.6 0.0 0.0 0.7 0.5 0.3 1.7 1.8 2.8 0.7 11.3 2.1 2.5 2.4 3.4 0.4 0.0 0.1 3.9 0.6 0.0 0.0 4.9 0.0 0.2 1.0 0.1 1.2 2.0 5.5 0.0 2.5 0.1 2.1 3.5 S1PR1 "CD363, D1S3362, edg-1, EDG1" ENSG00000170989 "Sphingosine-1-phosphate receptor 1" P21453 1 101236865-101243713 "Cancer-related genes, CD markers, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "Angiogenesis, Chemotaxis" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 236.1;Endothelial cells: 122.3;Hepatic stellate cells: 114.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 1248.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ: 73.0;HUVEC TERT2: 198.9;TIME: 113.3;U-251 MG: 147.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010104, HPA075568" Supported Supported Vesicles No NA "Cluster 38: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "CAB010104: AB_2238920, HPA075568: AB_2686758" "unprognostic (1.41e-1)" "unprognostic (9.35e-2)" "unprognostic (2.46e-2)" "unprognostic (2.61e-1)" "unprognostic (9.78e-2)" "unprognostic (4.49e-3)" "unprognostic (1.34e-3)" "unprognostic (1.99e-1)" "unprognostic (1.36e-1)" "unprognostic (9.12e-2)" "unprognostic (2.34e-2)" "unprognostic (2.23e-1)" "unprognostic (5.82e-3)" "unprognostic (2.54e-2)" "unprognostic (1.04e-1)" "unprognostic (3.64e-1)" "prognostic unfavorable (8.78e-4)" 114.7 14.4 58.8 29.8 62.7 18.5 91.9 59.8 59.0 18.5 27.8 19.5 9.4 24.7 3.9 26.8 22.9 28.0 71.8 51.3 65.1 18.0 31.3 78.3 46.3 65.2 73.0 8.2 20.3 23.3 8.7 48.1 61.3 13.7 10.1 14.6 15.0 7.8 27.9 17.9 22.3 31.2 57.6 63.1 17.1 2.6 76.5 21.4 35.9 51.5 26.9 34.3 19.2 52.6 15.6 0.2 14.2 0.0 1.4 32.7 0.1 73.0 13.5 47.9 16.6 0.1 0.7 0.0 17.8 25.2 0.4 0.0 1.8 0.8 27.0 6.1 1.2 6.8 0.3 0.0 6.6 0.0 3.5 45.0 0.3 0.1 3.7 1.7 198.9 5.8 0.2 14.4 13.5 0.0 20.6 0.0 3.9 0.4 4.8 0.0 13.4 0.5 0.1 0.0 0.0 0.1 0.7 0.0 0.2 0.9 0.0 0.2 113.3 6.8 2.9 2.0 147.1 1.3 0.0 1.0 0.7 0.0 0.4 1248.4 2.2 55.4 589.4 2.1 441.5 294.7 502.6 492.1 2.6 346.9 383.3 396.3 15.4 397.5 3.4 3.1 329.4 438.7 58.8 62.7 59.8 59.0 51.3 65.1 65.2 73.0 61.3 57.6 76.5 52.6 236.1 0.0 8.9 37.9 36.0 7.6 0.2 0.0 2.2 0.4 1.1 1.1 23.8 2.8 1.3 0.0 0.0 5.9 25.0 0.0 0.0 0.0 0.0 1.1 1.0 122.3 0.0 0.4 0.1 0.0 0.3 11.7 0.5 1.8 7.6 9.7 114.2 8.9 9.9 0.0 0.3 0.0 0.0 6.5 5.7 0.0 0.9 3.0 5.4 13.1 9.9 31.1 40.2 0.5 0.2 0.0 0.0 0.0 18.2 0.5 0.0 0.1 0.0 1.4 0.0 3.6 4.8 0.7 0.7 0.6 5.1 2.6 29.9 1.8 0.1 0.4 S1PR5 "Edg-8, EDG8" ENSG00000180739 "Sphingosine-1-phosphate receptor 5" Q9H228 19 10512742-10517931 "FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 19.7;brain: 60.2" "Cell type enhanced" "Detected in some" "dendritic cells: 93.9;NK-cells: 164.8;Oligodendrocytes: 26.6;T-cells: 33.1" "Group enriched" "Detected in many" 5 "cervical cancer: 11.7;head and neck cancer: 8.0;lung cancer: 3.7;urothelial cancer: 6.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 299.4;MAIT T-cell: 184.9;memory CD8 T-cell: 144.9;naive CD8 T-cell: 109.3" "Lineage enriched" "Detected in many" 7 "T-cells: 299.4" "Cell line enhanced" "Detected in many" "HaCaT: 28.5;HBEC3-KT: 10.9;RT4: 18.7;T-47d: 11.6;U-2 OS: 10.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029683 Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" "HPA029683: AB_10603237" "unprognostic (9.07e-3)" "unprognostic (1.27e-1)" "unprognostic (1.28e-2)" "unprognostic (5.55e-4)" "unprognostic (4.21e-1)" "unprognostic (4.85e-2)" "unprognostic (9.30e-2)" "unprognostic (1.55e-1)" "unprognostic (3.48e-2)" "unprognostic (2.29e-1)" "unprognostic (1.81e-1)" "unprognostic (1.27e-1)" "prognostic unfavorable (6.71e-7)" "unprognostic (2.46e-2)" "unprognostic (2.90e-2)" "unprognostic (1.19e-1)" "unprognostic (1.52e-1)" 0.8 0.4 21.1 0.8 35.7 19.7 0.6 32.4 44.7 5.4 8.6 0.3 0.2 0.3 4.4 12.8 0.2 0.2 0.6 19.7 23.2 0.8 1.6 3.0 1.0 39.0 34.0 0.2 1.4 0.1 0.4 1.7 35.8 2.5 0.1 0.0 2.4 0.5 0.6 18.7 0.3 0.2 26.0 11.1 0.3 0.7 30.1 0.9 0.5 0.2 2.1 2.2 10.9 60.2 1.9 2.8 0.6 0.0 0.0 0.1 0.2 0.6 0.5 0.9 0.5 0.3 0.1 0.0 7.6 0.3 1.2 28.5 1.8 10.9 2.0 0.0 1.8 0.2 2.3 0.0 0.1 0.0 0.1 0.0 5.0 3.0 0.6 0.2 0.0 0.0 0.2 0.0 0.0 3.7 1.1 0.0 4.5 0.6 0.5 0.0 2.1 0.0 0.0 18.7 0.0 0.0 4.7 0.0 0.5 1.9 11.6 3.3 0.0 1.5 10.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.3 0.5 0.5 1.2 299.4 0.2 184.9 0.6 36.3 144.9 0.6 0.5 10.8 109.3 3.9 44.5 1.1 0.8 0.6 64.2 21.1 35.7 32.4 44.7 19.7 23.2 39.0 34.0 35.8 26.0 30.1 60.2 1.0 3.2 1.9 0.0 0.6 3.6 2.2 10.9 7.4 0.0 0.1 0.9 0.9 1.5 0.9 0.0 0.0 0.1 93.9 0.0 0.0 0.0 6.2 0.1 0.2 0.6 0.0 0.8 0.1 0.2 0.3 1.7 0.5 0.0 2.5 0.0 1.8 0.3 0.2 0.0 0.1 0.0 0.0 0.8 0.3 2.3 0.0 0.6 0.0 2.8 1.2 0.0 164.8 0.0 26.6 0.2 0.0 0.0 14.7 0.2 0.0 0.1 0.4 0.0 0.0 0.1 1.9 0.0 0.2 4.8 5.1 0.1 33.1 0.0 0.0 0.4 SAMM50 "CGI-51, OMP85, SAM50, TOB55, TRG-3, YNL026W" ENSG00000100347 "SAMM50 sorting and assembly machinery component" Q9Y512 22 43955442-44010531 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 240.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034537 Enhanced Supported Mitochondria NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA034537: AB_10602794" "unprognostic (2.92e-1)" "unprognostic (1.01e-1)" "unprognostic (1.95e-3)" "prognostic favorable (2.63e-7)" "unprognostic (2.43e-3)" "unprognostic (2.28e-1)" "unprognostic (5.28e-3)" "unprognostic (1.70e-3)" "unprognostic (3.37e-2)" "unprognostic (1.95e-1)" "unprognostic (2.42e-1)" "unprognostic (3.52e-1)" "prognostic favorable (4.43e-8)" "unprognostic (1.08e-1)" "unprognostic (1.51e-1)" "unprognostic (2.41e-1)" "unprognostic (1.60e-1)" 41.7 50.6 26.1 27.0 27.0 32.5 35.8 29.8 30.6 43.4 31.1 35.6 50.8 27.0 29.3 31.7 41.9 29.3 65.5 27.1 29.2 48.8 37.2 22.2 34.6 29.8 28.5 40.0 33.3 114.4 24.4 20.1 30.4 26.5 35.5 25.5 35.2 25.1 240.4 35.9 38.3 27.7 27.0 24.4 43.8 26.1 28.5 34.4 28.1 177.0 37.0 27.9 24.0 28.0 64.6 59.8 57.1 69.5 72.2 75.9 79.8 61.7 65.7 89.1 76.4 86.1 46.0 105.9 44.3 70.8 51.4 75.6 85.4 82.6 79.7 29.4 105.3 57.5 73.9 102.6 50.4 184.0 83.1 88.3 64.7 77.0 35.5 62.3 93.1 49.9 49.9 34.0 80.9 91.7 72.6 72.0 56.0 77.4 70.9 83.8 61.8 85.9 74.4 81.0 34.1 55.4 68.3 72.2 104.1 60.4 67.7 59.8 57.7 57.3 68.8 53.6 51.2 50.1 74.4 82.1 72.0 66.3 58.7 47.5 39.2 46.9 39.8 39.0 55.4 55.1 36.6 40.5 67.7 51.0 37.8 36.0 6.1 39.1 31.8 26.7 45.7 40.2 26.1 27.0 29.8 30.6 27.1 29.2 29.8 28.5 30.4 27.0 28.5 28.0 52.9 35.3 18.9 10.4 31.6 20.6 27.0 72.0 30.7 20.1 32.1 40.9 68.6 18.6 39.5 9.2 8.4 41.6 31.7 36.1 60.7 47.2 40.3 47.3 24.9 35.1 18.6 51.4 12.0 55.5 54.1 24.6 42.3 32.7 27.3 43.9 30.0 41.8 51.1 32.0 12.7 35.2 46.8 28.6 20.5 50.1 26.1 25.0 16.0 12.2 41.4 32.8 33.0 9.5 9.1 43.7 34.5 30.5 31.0 16.2 82.4 116.8 39.9 30.1 19.7 23.2 33.4 45.8 31.2 34.3 22.6 20.5 28.5 69.9 59.8 19.3 SART1 "Ara1, HAF, SNRNP110, Snu66" ENSG00000175467 "Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP" O43290 11 65961728-65980137 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Allergen, Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031188, HPA031189, HPA031190" Supported Enhanced "Nuclear speckles,Golgi apparatus" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles" "Golgi apparatus" "HPA031188: AB_10600092, HPA031189: AB_10601854, HPA031190: AB_10602289" "unprognostic (2.93e-2)" "unprognostic (1.13e-2)" "unprognostic (1.09e-2)" "unprognostic (1.76e-1)" "unprognostic (1.45e-1)" "unprognostic (6.99e-2)" "unprognostic (2.52e-3)" "unprognostic (8.15e-2)" "unprognostic (8.97e-2)" "unprognostic (2.10e-1)" "unprognostic (2.11e-2)" "unprognostic (3.05e-1)" "unprognostic (1.39e-1)" "unprognostic (1.04e-1)" "unprognostic (1.58e-1)" "unprognostic (1.62e-1)" "unprognostic (4.24e-2)" 24.6 18.3 15.5 18.3 16.8 41.6 23.1 15.4 17.4 29.2 14.7 26.0 15.6 29.1 8.0 22.7 25.6 8.6 23.2 14.9 16.1 20.4 21.8 22.9 20.3 16.6 16.2 29.2 25.8 11.7 21.4 14.0 15.9 21.7 7.7 8.0 22.2 14.4 38.1 32.0 24.3 10.9 14.6 32.7 24.8 23.5 15.7 20.9 23.5 13.0 13.3 26.2 24.6 17.9 50.4 60.8 27.2 36.8 26.1 20.7 40.8 37.5 27.2 43.8 28.6 44.2 34.3 56.9 42.4 33.8 52.9 48.7 34.6 35.6 22.0 45.8 33.5 65.6 43.6 41.4 39.0 57.4 52.7 26.2 26.4 40.8 36.3 17.4 27.6 42.3 42.2 39.8 25.6 92.6 74.0 83.5 45.7 27.3 55.9 80.8 39.0 60.7 18.4 33.7 30.5 43.0 35.6 37.2 45.5 12.6 41.7 47.0 40.6 54.5 53.0 53.9 54.1 59.6 49.4 48.3 45.0 28.8 47.0 1.4 2.8 8.1 4.3 3.5 3.6 3.9 4.8 4.4 3.6 3.5 3.5 3.9 4.1 2.8 2.0 3.2 5.4 1.8 15.5 16.8 15.4 17.4 14.9 16.1 16.6 16.2 15.9 14.6 15.7 17.9 17.5 6.4 9.1 7.8 27.8 22.7 24.0 12.2 17.6 19.2 12.2 9.1 9.4 21.5 11.3 16.5 10.4 34.1 27.2 30.5 5.9 23.7 9.0 14.2 16.3 19.8 12.5 32.8 5.1 29.3 31.9 17.6 21.9 16.8 32.4 21.8 21.0 15.6 29.4 16.8 4.8 26.5 16.2 22.5 23.6 8.7 37.0 22.9 17.8 6.5 35.7 23.8 34.0 7.1 7.8 26.3 20.1 33.1 31.2 20.5 28.3 18.5 17.5 26.0 32.9 27.6 34.9 26.7 29.7 18.3 21.7 45.3 28.4 15.5 27.5 18.2 SCAF4 "DKFZp434E098, KIAA1172, SFRS15, SRA4" ENSG00000156304 "SR-related CTD associated factor 4" O95104 21 31671000-31732118 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018319, HPA018668, HPA021504, HPA028807" Enhanced Enhanced Nucleoplasm NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" Nucleoplasm "HPA018319: AB_1856784, HPA018668: AB_1856783, HPA021504: AB_1856785, HPA028807: AB_10602927" "unprognostic (9.18e-2)" "unprognostic (1.17e-1)" "unprognostic (9.29e-2)" "unprognostic (1.79e-1)" "unprognostic (1.88e-1)" "unprognostic (1.85e-2)" "unprognostic (3.99e-3)" "unprognostic (4.31e-1)" "unprognostic (2.19e-1)" "unprognostic (2.66e-2)" "unprognostic (3.28e-1)" "unprognostic (6.11e-2)" "unprognostic (1.85e-3)" "unprognostic (2.87e-1)" "unprognostic (7.65e-3)" "unprognostic (1.10e-1)" "unprognostic (2.16e-3)" 14.1 10.6 6.8 12.7 7.3 13.7 13.2 9.3 9.0 14.9 5.5 14.1 12.3 14.6 9.1 16.1 12.8 8.5 11.3 7.1 9.7 9.6 17.1 14.2 18.4 7.8 7.4 16.1 11.8 11.4 11.2 12.7 7.1 12.5 10.1 10.6 13.0 9.0 17.9 18.5 16.3 9.5 5.4 16.3 13.4 17.5 7.3 18.9 11.4 10.8 17.2 13.3 15.1 8.6 31.4 20.5 40.3 29.4 21.4 16.1 27.4 22.6 23.8 23.7 22.0 39.5 22.2 63.9 13.4 22.3 25.9 18.9 44.3 22.1 25.8 28.6 25.8 50.9 16.8 33.4 24.5 54.8 20.5 18.2 24.6 31.6 27.1 15.1 20.9 25.0 68.4 32.4 19.9 41.7 58.4 39.7 51.7 30.5 17.3 57.1 44.8 21.1 16.5 24.3 27.5 29.7 34.9 26.8 19.7 22.1 20.7 36.7 24.4 24.5 23.6 23.5 23.5 20.6 20.7 72.0 17.6 43.4 23.3 6.6 7.9 10.9 9.7 10.6 9.6 10.9 5.6 9.3 9.7 9.7 6.5 7.2 4.0 7.6 9.6 6.8 5.2 8.1 6.8 7.3 9.3 9.0 7.1 9.7 7.8 7.4 7.1 5.4 7.3 8.6 16.5 6.4 14.5 25.8 46.5 46.7 35.5 15.2 53.5 22.8 23.0 13.8 9.4 18.6 13.8 11.0 25.0 16.6 31.2 39.4 3.9 16.4 9.9 14.9 26.7 19.9 19.8 48.4 34.9 14.0 17.8 21.6 19.4 22.9 11.4 21.9 18.9 24.4 15.7 21.9 34.5 18.7 22.4 23.1 37.8 3.8 22.1 22.7 33.8 36.5 24.5 12.5 32.0 34.7 45.5 17.9 23.4 14.3 23.9 31.2 31.6 6.7 18.2 24.6 13.1 29.9 18.3 25.6 23.9 41.7 41.1 18.9 33.1 12.5 22.2 33.5 SCGB2A1 "LPHC, MGB2, MGC71973, UGB3" ENSG00000124939 "Secretoglobin family 2A member 1" O75556 11 62208673-62213943 "Cancer-related genes, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "cervix: 2021.0;epididymis: 1372.0" "Group enriched" "Detected in many" 6 "Endometrial ciliated cells: 2506.4;Glandular and luminal cells: 2597.0" "Cancer enriched" "Detected in many" 5 "endometrial cancer: 971.9" "Region enhanced" "Detected in some" "medulla oblongata: 3.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "EFO-21: 8.6" HPA034584 Enhanced Approved Vesicles "Secreted in other tissues" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 38: EFO-21 - Unknown function" "Cluster 44: Endometrium - Transcription" Vesicles "HPA034584: AB_10602221" "unprognostic (7.73e-2)" "unprognostic (3.77e-1)" "prognostic favorable (1.22e-4)" "prognostic favorable (1.54e-8)" "unprognostic (2.98e-2)" "unprognostic (1.86e-2)" "unprognostic (3.39e-1)" "unprognostic (1.95e-1)" "unprognostic (2.69e-1)" "unprognostic (6.87e-3)" "prognostic favorable (6.36e-4)" "unprognostic (5.67e-2)" "unprognostic (1.19e-1)" "unprognostic (1.18e-3)" "unprognostic (3.35e-1)" 0.2 0.0 0.0 0.2 0.0 0.0 57.8 0.0 0.0 2021.0 0.1 12.7 1.3 118.8 1372.0 4.2 238.4 13.4 0.2 0.1 0.4 1.9 0.1 2.4 0.0 3.5 1.4 0.7 17.2 1.1 5.1 0.1 0.8 6.8 16.3 0.0 29.6 15.6 0.0 8.6 1.0 2.2 0.5 0.0 45.9 0.0 1.1 2.7 5.8 0.0 0.1 0.3 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.3 0.0 0.1 0.0 0.7 0.1 0.0 1.6 0.4 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 3.5 1.4 0.8 0.5 1.1 0.2 0.6 0.0 4.8 0.0 0.4 0.1 3.8 4.8 0.0 0.0 123.6 71.0 0.0 48.6 10.1 16.5 0.0 0.2 1.6 9.7 3.9 6.6 0.0 2506.4 397.7 7.6 37.1 0.0 0.0 5.3 0.0 3.8 26.5 2597.0 0.0 0.3 0.0 0.1 4.9 0.0 0.0 59.9 10.2 0.3 0.0 0.0 0.0 14.1 5.4 0.0 0.0 0.0 0.0 0.0 0.0 15.3 10.8 0.0 0.0 27.0 0.7 0.1 109.3 0.0 0.0 0.0 8.5 0.0 0.0 1.7 0.4 0.0 13.7 0.1 7.0 16.6 SCGB2B2 "SCGB4A2, SCGBL" ENSG00000205209 "Secretoglobin family 2B member 2" Q4G0G5 19 34593329-34675699 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "pancreas: 8.6" "Cell type enhanced" "Detected in some" "Astrocytes: 63.6;Excitatory neurons: 32.8;Inhibitory neurons: 45.3;Late spermatids: 31.0;Oligodendrocyte precursor cells: 52.8;Oligodendrocytes: 104.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 1.2;U-266/70: 1.0" HPA046806 Uncertain "Secreted in other tissues" NA NA "Cluster 25: Pancreas - Digestion" "Cluster 29: U-266 - Adaptive immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA046806: AB_10962373" "unprognostic (9.99e-2)" "unprognostic (3.62e-1)" "unprognostic (9.51e-2)" "unprognostic (1.38e-5)" "unprognostic (4.80e-3)" "unprognostic (1.66e-1)" "unprognostic (2.03e-2)" "unprognostic (2.73e-2)" "unprognostic (1.79e-1)" "unprognostic (1.19e-1)" "unprognostic (1.75e-3)" "unprognostic (3.67e-1)" "unprognostic (3.52e-2)" "unprognostic (2.90e-1)" "unprognostic (2.49e-1)" "unprognostic (3.40e-2)" "unprognostic (1.52e-1)" 0.3 0.4 0.7 0.0 1.0 0.1 0.9 0.4 0.9 0.1 0.1 0.2 0.1 0.3 2.6 0.9 0.3 0.2 0.3 0.6 0.7 0.3 0.5 0.5 0.3 1.0 1.0 0.2 8.6 0.3 0.3 0.2 0.9 0.3 0.2 0.6 0.3 0.5 0.7 2.9 0.2 0.1 0.5 0.4 0.3 2.0 1.0 0.1 0.5 1.1 0.3 0.4 0.1 0.9 0.2 0.1 0.0 0.1 0.1 0.0 0.2 0.0 0.2 0.0 0.0 1.2 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.3 0.0 0.1 0.0 0.2 0.4 0.0 0.1 0.1 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.4 0.0 0.4 0.0 0.4 0.2 0.4 0.0 0.2 0.0 0.1 0.2 0.1 0.2 0.4 0.3 0.2 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.3 0.0 0.0 1.0 0.4 0.4 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.0 0.4 0.9 0.6 0.7 1.0 1.0 0.9 0.5 1.0 0.9 0.0 0.0 0.0 63.6 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 0.1 0.0 0.2 0.0 0.0 32.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 45.3 0.0 0.0 0.0 0.0 31.0 0.0 0.0 3.6 17.8 0.0 0.0 0.0 52.8 104.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 SCML4 dJ47M23.1 ENSG00000146285 "Scm polycomb group protein like 4" Q8N228 6 107702154-107824317 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 10.1;lymphoid tissue: 12.1" "Cell type enhanced" "Detected in many" "dendritic cells: 31.7;Early spermatids: 72.1;Late spermatids: 168.4;NK-cells: 35.0;T-cells: 73.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 6 "gdT-cell: 48.2;MAIT T-cell: 47.7;memory CD4 T-cell: 74.8;memory CD8 T-cell: 65.7;naive CD4 T-cell: 69.1;naive CD8 T-cell: 59.5;NK-cell: 53.2" "Group enriched" "Detected in many" 6 "NK-cells: 53.2;T-cells: 74.8" "Cell line enriched" "Detected in some" 5 "HDLM-2: 65.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA063326, HPA065958" Approved Approved Nucleoplasm NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 58: T-cells - T-cell receptor" Nucleoplasm "HPA063326: AB_2684986, HPA065958: AB_2685587" "unprognostic (4.00e-5)" "unprognostic (2.10e-3)" "unprognostic (4.71e-2)" "unprognostic (4.24e-3)" "unprognostic (1.38e-3)" "unprognostic (4.75e-4)" "unprognostic (3.84e-3)" "unprognostic (6.65e-3)" "unprognostic (4.26e-1)" "unprognostic (1.53e-2)" "unprognostic (2.13e-4)" "unprognostic (3.68e-1)" "unprognostic (3.77e-4)" "unprognostic (8.65e-2)" "unprognostic (3.68e-2)" "unprognostic (2.52e-3)" "unprognostic (5.09e-3)" 0.6 0.8 0.8 7.2 0.6 3.3 1.0 1.2 0.7 0.5 0.2 2.3 10.1 0.5 4.6 0.9 0.7 1.4 0.6 0.6 0.9 0.6 1.6 1.7 12.1 0.5 0.5 0.6 0.7 0.2 1.9 0.3 0.3 0.6 2.0 0.9 1.0 0.4 0.4 0.9 8.2 0.5 0.1 7.4 2.8 2.2 1.3 9.3 0.8 0.2 9.8 1.1 0.7 0.6 0.1 0.1 0.1 0.1 0.1 0.3 0.8 0.1 0.0 0.0 0.0 1.4 0.2 0.2 0.1 0.0 0.1 0.2 0.0 0.0 0.1 65.1 0.0 0.1 0.4 0.2 0.0 0.3 0.1 0.1 0.0 0.0 0.1 0.2 0.2 0.7 0.1 0.1 0.0 0.1 0.0 0.2 0.1 0.1 0.0 0.1 0.3 0.1 0.0 0.2 0.1 0.3 0.1 0.1 13.8 0.2 0.1 0.1 0.0 0.1 0.2 0.3 0.1 0.3 0.2 0.7 0.1 0.1 0.1 4.2 0.3 3.5 48.2 0.1 47.7 10.1 74.8 65.7 0.2 5.8 69.1 59.5 6.6 53.2 0.4 1.2 5.8 26.6 0.8 0.6 1.2 0.7 0.6 0.9 0.5 0.5 0.3 0.1 1.3 0.6 0.5 0.0 0.0 0.7 18.0 1.5 0.0 0.0 0.6 0.6 0.4 0.4 1.1 0.0 0.0 0.0 0.0 1.3 31.7 0.4 0.0 1.2 72.1 0.0 0.1 0.7 0.0 1.3 2.7 0.0 0.2 1.0 4.6 0.1 1.3 0.0 1.1 1.8 0.2 1.7 2.5 1.4 0.0 0.8 1.4 168.4 0.9 1.2 3.6 1.9 2.0 0.0 35.0 0.5 0.1 0.1 2.6 0.7 11.6 0.0 5.5 0.4 0.7 0.0 0.0 0.3 0.6 1.1 0.5 0.3 0.1 0.1 73.3 0.0 4.7 0.1 SDCBP2 "SITAC18, ST-2" ENSG00000125775 "Syndecan binding protein 2" Q9H190 20 1309909-1329139 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 141.8;intestine: 136.9;stomach 1: 101.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 782.5;Pancreatic endocrine cells: 755.4;Paneth cells: 948.5;Proximal enterocytes: 470.3;Urothelial cells: 641.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 18.6;OE19: 57.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA005804, HPA064490" Enhanced Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" Nucleoplasm "Golgi apparatus, Cytosol" "HPA005804: , HPA064490: AB_2732713" "unprognostic (1.96e-2)" "unprognostic (5.44e-2)" "unprognostic (2.37e-1)" "unprognostic (5.85e-2)" "unprognostic (2.54e-1)" "unprognostic (2.27e-2)" "unprognostic (2.57e-2)" "prognostic unfavorable (2.42e-4)" "unprognostic (1.01e-1)" "unprognostic (3.78e-3)" "prognostic unfavorable (3.07e-4)" "unprognostic (3.17e-1)" "unprognostic (1.07e-2)" "unprognostic (1.30e-1)" "unprognostic (1.69e-1)" "unprognostic (1.20e-1)" "prognostic favorable (3.37e-4)" 7.3 3.4 19.9 10.1 20.7 0.7 6.9 16.3 24.3 25.8 15.2 85.8 136.9 5.7 9.0 141.8 4.3 41.8 4.6 19.6 20.2 16.0 18.1 20.9 1.3 17.2 17.9 3.5 15.2 2.5 3.9 3.3 17.4 6.5 55.5 1.0 29.8 2.5 2.8 62.9 133.0 3.6 16.9 3.1 101.8 5.6 20.3 1.5 14.6 1.4 13.7 38.2 49.9 18.0 10.9 0.5 1.4 0.5 5.8 5.1 0.9 3.2 6.3 2.8 2.7 2.3 18.6 1.1 2.1 1.2 2.0 8.2 0.5 15.5 1.4 0.4 1.0 0.9 0.6 1.5 5.8 1.1 1.2 1.8 10.8 2.2 2.2 6.0 9.6 2.0 1.5 0.7 1.1 2.6 1.7 3.0 1.3 57.3 0.7 1.6 0.7 2.2 1.2 14.4 2.4 1.9 1.5 9.3 3.6 0.6 0.4 0.9 6.5 1.5 0.6 2.8 1.2 2.8 2.7 1.1 0.7 4.1 0.9 0.1 0.8 1.9 0.9 0.3 0.7 0.2 1.2 0.9 1.0 0.4 1.0 1.8 0.8 0.9 0.6 0.7 2.3 0.7 19.9 20.7 16.3 24.3 19.6 20.2 17.2 17.9 17.4 16.9 20.3 18.0 15.6 16.0 4.2 0.0 4.1 55.7 112.0 198.1 3.4 1.0 4.9 4.8 0.8 72.9 172.6 16.5 0.0 1.8 1.0 782.5 27.4 114.5 17.1 25.8 11.7 14.1 35.9 0.0 0.0 209.7 1.1 4.6 201.8 85.4 8.9 1.0 7.1 5.1 0.9 1.7 0.0 150.8 156.6 1.9 6.4 1.9 1.5 1.8 8.8 0.0 2.3 1.0 2.1 0.0 0.0 755.4 948.5 0.0 0.7 107.0 470.3 1.8 89.6 0.9 0.0 1.7 9.9 5.0 7.6 31.1 95.6 1.6 3.5 2.0 109.2 641.9 SDR42E1 HSPC105 ENSG00000184860 "Short chain dehydrogenase/reductase family 42E, member 1" Q8WUS8 16 81988855-82011481 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "skin 1: 9.2" "Cell type enhanced" "Detected in many" "Ductal cells: 10.0;Ionocytes: 10.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 2.3;NK-cells: 2.0;T-cells: 2.2" "Cell line enhanced" "Detected in some" "HaCaT: 9.5;hTCEpi: 12.1;MCF7: 8.3;RT4: 20.6;SCLC-21H: 8.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014388 Uncertain NA NA "Cluster 37: B-cells - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 15: RT4 - Unknown function" "Cluster 1: Pancreatic cells - Digestion" "HPA014388: AB_1851226" "unprognostic (2.09e-1)" "unprognostic (4.90e-1)" "unprognostic (9.52e-3)" "unprognostic (3.81e-1)" "unprognostic (3.46e-1)" "unprognostic (1.14e-2)" "unprognostic (1.38e-1)" "unprognostic (2.91e-2)" "unprognostic (1.60e-1)" "unprognostic (4.51e-2)" "unprognostic (3.96e-2)" "unprognostic (4.93e-4)" "unprognostic (4.90e-7)" "unprognostic (2.18e-1)" "unprognostic (1.82e-1)" "unprognostic (3.21e-2)" "unprognostic (8.27e-2)" 0.5 0.1 0.0 0.9 0.1 0.4 4.4 0.0 0.1 1.2 0.1 2.4 5.6 1.3 1.9 3.6 1.7 1.1 0.6 0.0 0.2 1.9 1.8 1.6 1.3 0.1 0.1 0.3 3.2 2.1 1.3 0.3 0.1 1.7 1.7 0.0 3.1 0.9 0.0 9.2 4.7 1.1 0.0 0.8 2.6 1.1 0.2 1.6 1.9 0.0 2.4 2.3 2.4 0.0 3.7 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 4.9 0.0 1.8 0.0 0.4 9.5 0.0 6.5 0.0 0.0 0.6 0.0 1.7 0.0 0.3 0.0 0.0 0.3 12.1 1.5 5.9 0.0 0.0 0.0 1.6 0.0 0.8 8.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.8 2.5 20.6 8.2 0.0 0.2 4.3 0.0 0.2 0.1 0.0 0.2 0.0 4.3 0.0 0.0 4.0 5.9 0.4 0.0 0.0 0.0 0.0 0.0 0.4 0.8 0.0 1.1 2.3 0.7 1.2 0.1 1.0 2.2 1.6 0.0 2.0 0.0 0.1 1.5 0.9 0.0 0.1 0.0 0.1 0.0 0.2 0.1 0.1 0.1 0.0 0.2 0.0 1.0 0.0 1.1 0.0 2.7 5.9 3.5 6.1 6.2 0.0 5.8 3.9 2.6 7.2 3.3 1.8 0.0 0.6 1.1 2.7 3.9 10.0 1.3 2.8 0.7 0.5 2.4 0.4 0.0 7.5 0.2 0.4 1.1 3.2 0.0 0.4 0.0 3.7 0.0 0.0 0.0 6.0 10.2 0.0 0.3 2.0 0.0 0.2 1.8 0.0 0.0 0.0 1.0 0.0 0.1 6.3 4.5 0.0 1.1 3.8 9.7 2.9 3.6 0.0 0.0 0.0 0.5 8.4 6.2 5.6 9.1 0.3 1.2 0.1 4.1 4.4 SELENOI "EPT1, KIAA1724, SELI, SEPI" ENSG00000138018 "Selenoprotein I" Q9C0D9 2 26308547-26395891 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" Transferase "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Collecting duct cells: 22.0;Endometrial ciliated cells: 16.3;Glandular and luminal cells: 15.3;Pancreatic endocrine cells: 13.6;Syncytiotrophoblasts: 16.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064125 Approved NA NA "Cluster 37: B-cells - Transcription" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" "HPA064125: " "unprognostic (6.29e-2)" "unprognostic (7.46e-2)" "unprognostic (1.38e-3)" "unprognostic (3.05e-3)" "unprognostic (1.50e-1)" "unprognostic (1.39e-2)" "unprognostic (7.44e-3)" "unprognostic (5.00e-3)" "unprognostic (7.79e-2)" "unprognostic (2.55e-2)" "unprognostic (6.65e-2)" "unprognostic (9.40e-2)" "unprognostic (1.52e-2)" "unprognostic (2.95e-1)" "unprognostic (1.76e-1)" "unprognostic (9.87e-3)" "unprognostic (1.42e-2)" 3.6 6.4 7.9 5.5 8.4 12.1 8.1 11.2 10.6 5.4 5.0 8.6 12.3 4.1 5.4 11.1 3.5 4.0 3.9 10.3 9.3 7.9 23.2 4.4 5.7 6.8 7.3 3.5 9.0 17.2 4.5 4.7 8.6 6.2 8.7 9.3 6.2 4.2 7.0 18.3 18.4 3.7 9.7 4.3 7.1 4.4 7.2 6.3 7.1 6.6 6.1 7.5 7.1 10.0 42.7 25.7 20.9 21.0 12.8 10.2 32.0 20.3 9.2 10.0 10.2 54.5 26.6 49.5 24.2 9.5 21.4 34.1 32.4 17.9 14.4 13.7 15.4 31.3 17.5 32.3 12.2 41.9 9.7 8.1 15.6 22.3 21.9 6.1 9.4 17.6 35.9 16.6 13.5 18.4 25.1 20.7 26.8 21.6 17.4 22.6 49.2 25.0 19.3 32.4 45.7 19.4 17.3 36.2 16.4 17.3 17.4 12.4 15.1 17.1 22.0 22.7 31.7 22.6 60.8 65.8 17.5 25.4 15.6 0.0 0.7 0.0 0.9 1.0 0.9 2.5 0.9 1.2 0.7 1.0 1.2 2.0 0.2 0.9 0.9 1.3 1.8 0.4 7.9 8.4 11.2 10.6 10.3 9.3 6.8 7.3 8.6 9.7 7.2 10.0 9.1 12.8 8.7 0.0 3.0 0.0 0.0 0.0 0.0 0.0 12.2 7.1 0.0 0.0 3.1 22.0 0.0 6.1 11.7 0.0 0.0 10.4 0.0 16.3 12.8 3.7 0.0 0.0 0.0 10.4 6.2 2.9 0.0 15.3 1.3 8.6 0.0 0.0 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 13.6 0.0 0.0 3.9 0.0 0.0 5.6 2.2 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 16.6 4.7 11.5 0.0 0.0 SEMA4B "KIAA1745, MGC131831, SEMAC, SemC" ENSG00000185033 "Semaphorin 4B" Q9NPR2 15 90160604-90229679 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 124.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 16.9;naive B-cell: 14.9;neutrophil: 5.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "CAPAN-2: 182.4;RPTEC TERT1: 111.1;RT4: 124.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013372 Approved Approved "Nucleoplasm,Vesicles,Cell Junctions" NA NA 61000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Cell Junctions" "Nucleoplasm, Vesicles" "HPA013372: AB_1856670" "unprognostic (3.33e-2)" "unprognostic (5.96e-2)" "unprognostic (2.23e-2)" "unprognostic (2.50e-2)" "unprognostic (7.78e-2)" "unprognostic (4.48e-2)" "unprognostic (6.34e-3)" "prognostic unfavorable (1.25e-4)" "unprognostic (2.04e-1)" "unprognostic (9.31e-2)" "unprognostic (1.58e-3)" "unprognostic (4.67e-2)" "prognostic unfavorable (3.33e-8)" "unprognostic (1.66e-1)" "unprognostic (1.23e-2)" "unprognostic (3.57e-2)" "unprognostic (7.09e-2)" 11.9 37.6 20.3 18.0 21.9 9.8 22.5 18.8 21.6 35.1 12.8 50.2 30.2 17.1 8.2 124.4 22.6 17.1 24.9 17.3 21.0 47.7 43.2 20.5 12.0 23.5 24.0 21.6 38.5 18.1 18.6 18.3 21.4 31.4 12.1 27.1 41.2 17.6 7.8 50.9 34.7 13.3 21.0 30.3 32.2 10.7 22.9 13.2 34.2 7.9 13.0 42.2 59.8 26.8 21.2 56.3 4.2 13.2 3.8 2.6 30.4 6.4 13.9 7.8 8.3 7.0 182.4 14.9 69.2 4.7 45.0 97.8 3.7 91.2 6.4 85.4 11.7 19.7 13.5 9.4 15.1 2.6 8.7 10.8 39.1 8.5 17.5 32.5 8.8 4.4 9.6 23.0 4.3 15.6 5.4 8.4 18.7 46.8 51.1 6.4 3.1 33.1 111.1 124.0 13.3 13.5 22.3 35.4 8.5 9.3 24.7 6.0 20.0 6.3 11.4 13.1 14.5 33.0 43.2 7.5 58.8 16.1 6.3 0.0 2.4 0.3 0.9 1.4 0.6 16.9 0.5 0.5 1.2 14.9 0.5 0.6 5.1 0.4 2.8 0.2 0.2 1.5 20.3 21.9 18.8 21.6 17.3 21.0 23.5 24.0 21.4 21.0 22.9 26.8 1.8 16.0 22.5 67.3 29.2 65.0 40.0 51.4 23.9 5.7 29.1 18.9 7.8 8.6 44.6 16.5 25.0 13.9 2.4 47.8 3.9 27.3 0.9 15.6 19.6 4.4 4.2 4.0 23.5 35.5 74.5 6.4 34.1 28.3 0.0 8.6 4.6 16.8 13.3 16.8 28.2 17.5 18.3 6.9 7.5 1.2 13.1 5.5 5.4 2.8 5.3 25.1 1.0 8.0 8.3 44.7 26.1 12.0 8.0 46.9 19.6 4.5 22.6 48.3 19.7 5.7 15.3 0.7 3.2 65.3 57.1 12.4 4.3 5.2 20.2 52.0 SEMA4D "C9orf164, CD100, coll-4, FLJ39737, SEMAJ" ENSG00000187764 "Semaphorin 4D" Q92854 9 89360787-89498130 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 260.2" "Cell type enhanced" "Detected in many" "dendritic cells: 76.5;NK-cells: 92.7;Oligodendrocytes: 310.5;T-cells: 89.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 133.2;HMC-1: 97.2;JURKAT: 89.1;MOLT-4: 120.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015662, HPA023277" Approved NA NA 7500000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA015662: AB_1856671, HPA023277: AB_1856672" "unprognostic (2.94e-2)" "prognostic favorable (4.17e-4)" "unprognostic (1.12e-2)" "unprognostic (8.22e-2)" "unprognostic (1.41e-1)" "unprognostic (1.76e-3)" "unprognostic (1.27e-1)" "unprognostic (1.58e-1)" "unprognostic (7.79e-2)" "unprognostic (2.74e-1)" "unprognostic (3.18e-3)" "unprognostic (1.50e-2)" "unprognostic (2.29e-3)" "unprognostic (3.05e-2)" "unprognostic (1.28e-2)" "unprognostic (2.43e-1)" "prognostic favorable (4.06e-5)" 7.2 12.8 73.5 35.1 149.7 28.7 6.1 129.0 122.7 9.1 34.2 10.4 10.6 6.5 12.2 27.3 11.0 12.3 12.1 72.0 88.4 32.0 4.1 14.2 62.4 165.2 145.6 6.5 8.0 6.0 13.8 5.5 147.8 11.9 9.7 5.0 12.0 6.6 88.0 17.4 28.9 5.5 119.1 51.3 16.7 10.6 127.0 43.4 11.8 27.5 49.8 11.4 16.2 260.2 12.7 9.2 8.4 12.4 0.4 0.8 19.0 1.1 0.5 2.6 1.7 6.1 13.8 47.3 5.1 0.2 9.7 6.4 7.5 3.6 1.1 133.2 7.5 20.1 3.3 0.7 1.5 26.4 97.2 0.3 2.8 0.6 0.3 0.3 4.9 89.1 4.8 31.5 0.0 20.9 120.9 33.9 20.6 25.0 0.5 38.2 2.8 13.4 16.5 13.0 19.7 13.1 3.4 8.9 0.3 11.7 10.1 14.4 3.2 0.1 7.6 1.0 6.1 34.9 16.3 6.6 6.0 32.1 7.6 17.2 7.5 38.2 22.0 7.0 13.3 4.3 17.5 18.6 2.6 2.5 19.9 23.2 37.0 9.4 8.1 8.0 17.7 14.5 73.5 149.7 129.0 122.7 72.0 88.4 165.2 145.6 147.8 119.1 127.0 260.2 3.4 6.4 15.7 33.6 35.4 4.6 3.3 2.1 3.4 12.4 9.5 5.5 18.7 5.7 6.9 11.0 2.1 9.0 76.5 1.5 3.9 5.4 2.2 10.9 6.4 5.2 1.8 23.1 44.5 3.3 2.1 6.7 7.7 15.4 42.5 8.0 5.3 1.6 21.6 33.7 17.2 6.3 4.1 28.2 6.1 3.8 7.5 37.4 1.8 49.6 43.7 8.9 92.7 12.1 310.5 3.7 0.7 15.1 53.7 6.5 0.5 14.2 5.7 5.1 0.0 11.4 2.6 0.9 26.1 7.1 5.4 3.7 89.7 2.3 3.3 7.7 SEMA4G "FLJ20590, KIAA1619" ENSG00000095539 "Semaphorin 4G" Q9NTN9 10 100969518-100985871 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 84.6;liver: 102.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 66.4;Gastric mucus-secreting cells: 27.0;Hepatocytes: 60.5;Intestinal goblet cells: 34.6;Paneth cells: 38.5;Proximal enterocytes: 47.6;Undifferentiated cells: 45.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 31.7;CACO-2: 30.5;Hep G2: 113.8;OE19: 69.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038362, HPA077752" Uncertain Uncertain "Vesicles,Lipid droplets" "Intracellular and membrane" NA NA 1300000 "Cluster 37: B-cells - Transcription" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Vesicles, Lipid droplets" "HPA038362: AB_10669524, HPA077752: " "unprognostic (3.90e-3)" "unprognostic (9.43e-3)" "unprognostic (2.84e-1)" "unprognostic (1.13e-2)" "unprognostic (5.55e-2)" "unprognostic (8.11e-2)" "unprognostic (3.28e-1)" "unprognostic (3.71e-2)" "unprognostic (3.63e-1)" "unprognostic (1.41e-2)" "unprognostic (3.09e-2)" "unprognostic (3.14e-1)" "unprognostic (3.93e-2)" "unprognostic (2.04e-2)" "unprognostic (1.59e-1)" "unprognostic (1.17e-1)" "unprognostic (3.05e-2)" 2.4 12.7 13.1 5.9 10.9 0.4 3.6 18.9 12.3 6.9 12.8 53.6 53.4 3.5 32.1 3.6 5.9 9.0 3.0 10.0 11.6 19.1 102.4 5.8 2.5 11.2 14.4 18.9 31.3 7.3 9.9 3.9 11.5 20.2 84.6 7.3 8.5 3.0 2.6 18.3 41.2 4.6 9.6 3.1 20.9 3.7 17.0 0.8 15.3 0.8 0.9 4.0 5.0 9.9 0.2 31.7 8.0 3.4 5.0 1.6 6.8 1.2 3.4 1.7 1.7 30.5 5.2 0.5 4.2 1.5 0.6 2.1 8.0 1.4 1.4 0.7 4.9 1.7 3.0 113.8 12.5 1.2 1.0 8.3 1.8 1.6 0.9 22.2 4.4 3.5 3.3 0.4 2.5 2.0 0.5 1.2 1.3 69.1 1.8 3.1 0.7 1.5 7.4 1.0 2.5 12.5 1.1 2.1 3.2 8.7 8.7 1.5 3.0 1.0 3.7 0.8 0.3 1.1 0.6 0.5 0.9 1.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.1 10.9 18.9 12.3 10.0 11.6 11.2 14.4 11.5 9.6 17.0 9.9 0.3 3.2 1.1 3.9 1.2 0.0 0.6 0.7 0.6 3.5 2.5 2.0 1.2 20.0 0.2 0.0 0.0 8.8 0.0 66.4 0.0 2.7 0.2 1.6 0.7 0.6 8.5 0.8 3.0 2.6 1.9 2.0 27.0 0.3 0.0 3.4 2.2 60.5 0.9 11.8 14.1 34.6 2.0 3.3 0.0 0.2 2.1 0.2 1.8 0.0 0.0 0.9 0.0 3.5 5.5 2.4 38.5 1.2 0.2 3.0 47.6 6.4 2.4 1.6 0.0 0.1 0.4 1.1 1.9 0.5 0.1 2.9 0.2 12.7 45.9 0.9 SEPTIN8 "KIAA0202, SEP2, SEPT8" ENSG00000164402 "Septin 8" Q92599 5 132750819-132807241 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 393.6" "Cell type enhanced" "Detected in some" "Adipocytes: 7.0;Cardiomyocytes: 14.1;Cytotrophoblasts: 31.0;Extravillous trophoblasts: 12.1;Fibroblasts: 9.5;Hofbauer cells: 12.1;Smooth muscle cells: 8.8;Syncytiotrophoblasts: 10.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005665, HPA036534" Enhanced Approved "Actin filaments,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 15: RT4 - Unknown function" "Cluster 24: Non-specific - Transcription regulation" Cytosol "Actin filaments" "HPA005665: AB_1079910, HPA036534: AB_2797226" "unprognostic (2.06e-2)" "unprognostic (1.13e-1)" "unprognostic (9.24e-2)" "unprognostic (7.10e-3)" "unprognostic (2.70e-1)" "unprognostic (2.15e-2)" "unprognostic (2.86e-2)" "unprognostic (1.41e-2)" "unprognostic (1.58e-2)" "unprognostic (2.97e-2)" "unprognostic (2.38e-2)" "unprognostic (3.12e-1)" "prognostic unfavorable (6.98e-5)" "unprognostic (2.86e-2)" "unprognostic (4.30e-1)" "unprognostic (8.04e-3)" "unprognostic (2.70e-1)" 26.9 19.5 192.8 18.0 273.3 8.3 22.2 279.1 238.2 28.2 111.6 26.3 26.2 18.8 18.5 34.0 21.4 25.2 33.0 188.3 218.5 34.8 13.0 26.2 14.9 319.9 262.0 25.2 23.3 23.9 22.3 44.3 304.7 20.5 26.9 74.6 33.4 20.6 10.9 49.7 25.8 21.3 238.1 14.8 26.8 6.9 250.4 18.0 32.3 12.4 18.6 36.1 31.1 393.6 55.8 26.4 37.3 76.7 50.8 49.5 122.0 58.9 56.2 54.7 66.5 46.6 39.2 0.3 51.1 57.3 32.4 42.3 70.5 96.4 59.9 71.3 50.8 54.4 35.5 40.5 37.2 19.4 76.0 35.9 30.6 25.3 35.8 53.5 77.4 47.7 84.6 10.6 29.7 53.0 63.3 18.2 19.8 33.7 17.0 57.4 43.5 4.7 32.0 141.1 50.0 31.0 50.0 11.5 32.9 107.4 100.6 25.4 80.9 60.6 39.2 15.1 42.5 14.3 14.3 2.0 38.7 28.6 46.5 0.5 1.0 0.0 2.0 0.6 2.0 0.4 1.6 2.5 1.2 0.1 0.4 1.0 0.0 0.2 0.3 0.0 1.9 1.0 192.8 273.3 279.1 238.2 188.3 218.5 319.9 262.0 304.7 238.1 250.4 393.6 7.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.1 0.0 0.0 0.0 0.0 31.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 12.1 9.5 0.0 0.0 0.0 0.0 0.0 0.0 12.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.8 0.0 0.0 0.0 0.0 10.1 0.6 0.0 0.0 0.0 SERPINA5 "PAI3, PCI, PLANH3, PROCI" ENSG00000188488 "Serpin family A member 5" P05154 14 94561442-94593118 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Fertilization, Lipid transport, Transport" "Heparin-binding, Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 484.5;liver: 785.6;testis: 432.4" "Cell type enhanced" "Detected in many" "Cholangiocytes: 400.4;Endometrial ciliated cells: 175.2;Glandular and luminal cells: 345.3;Hepatocytes: 198.2;Late spermatids: 277.8;Peritubular cells: 144.4" "Cancer enhanced" "Detected in many" "liver cancer: 121.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 15 "Hep G2: 261.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA078846 Enhanced "Secreted to blood" NA NA 2100000000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 44: Endometrium - Transcription" "HPA078846: " "unprognostic (5.94e-3)" "unprognostic (2.64e-4)" "unprognostic (1.13e-1)" "prognostic favorable (7.72e-4)" "unprognostic (3.34e-3)" "unprognostic (6.10e-3)" "unprognostic (3.94e-2)" "unprognostic (1.39e-3)" "unprognostic (5.36e-1)" "unprognostic (1.50e-1)" "unprognostic (6.16e-2)" "unprognostic (1.87e-2)" "unprognostic (8.39e-3)" "unprognostic (3.38e-3)" "unprognostic (9.92e-2)" "unprognostic (8.08e-2)" "unprognostic (3.23e-1)" 5.1 484.5 1.8 3.3 2.4 0.0 19.6 2.2 1.7 29.6 3.0 5.3 5.5 31.8 1.2 0.8 26.3 160.5 19.0 1.6 7.2 151.4 785.6 1.0 3.6 3.5 3.8 30.1 173.9 0.2 3.2 0.1 5.3 6.8 1.9 14.0 9.4 153.3 46.4 3.3 3.6 2.1 1.7 112.2 12.1 432.4 2.8 0.9 4.1 152.6 4.7 2.3 4.0 3.7 0.8 0.1 2.7 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 12.0 12.2 0.0 8.3 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 261.3 0.3 0.4 0.0 1.7 0.3 0.1 0.0 2.3 4.9 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.7 0.2 0.0 0.1 0.5 0.2 3.9 0.1 0.4 17.4 0.2 0.1 7.9 0.9 0.1 0.0 0.5 0.0 0.6 0.4 1.5 0.2 0.1 0.2 0.0 0.1 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 2.4 2.2 1.7 1.6 7.2 3.5 3.8 5.3 1.7 2.8 3.7 0.9 0.0 0.0 0.0 0.1 0.8 0.0 0.1 0.0 0.2 18.9 14.1 0.8 400.4 0.1 33.1 2.1 0.0 0.1 0.0 64.6 103.2 78.7 175.2 19.7 40.3 0.0 2.7 0.0 122.2 0.0 18.2 0.5 345.3 0.0 78.2 2.5 198.2 0.0 8.4 0.0 0.0 0.0 3.2 0.7 277.8 57.2 1.9 0.0 0.0 0.6 5.4 0.0 0.0 0.2 18.3 0.0 144.4 0.0 0.1 0.0 7.5 0.0 1.4 6.6 11.6 1.5 11.1 2.9 0.0 0.6 0.3 1.8 58.7 0.0 0.1 SERPINB2 "HsT1201, PAI2, PLANH2" ENSG00000197632 "Serpin family B member 2" P05120 18 63871692-63903888 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Plasminogen activation" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 239.1;lymphoid tissue: 81.2;skin 1: 89.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 2243.9;Suprabasal keratinocytes: 1053.6;Syncytiotrophoblasts: 439.3" "Cancer enhanced" "Detected in many" "head and neck cancer: 26.5" "Group enriched" "Detected in some" 6 "cerebral cortex: 1.3;thalamus: 1.1" "Immune cell enhanced" "Detected in some" "basophil: 22.0;eosinophil: 10.0" "Lineage enriched" "Detected in many" 4 "granulocytes: 22.0" "Cell line enhanced" "Detected in many" "GAMG: 282.7;HaCaT: 699.1;U-138 MG: 807.0;U-2197: 1243.9" "Region enriched" "Detected in single" 15 "cerebellum: 2.6" "Not detected" "Not detected" "HPA015480, HPA076596, HPA076608" Enhanced "Intracellular and membrane" NA NA 2200000 "Cluster 10: Basophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 18: U-2197 - ECM organization" "Cluster 28: Keratinocytes - Keratinization" "HPA015480: AB_1855456, HPA076596: , HPA076608: " "unprognostic (2.11e-1)" "unprognostic (1.74e-1)" "unprognostic (5.46e-2)" "unprognostic (1.36e-4)" "unprognostic (1.17e-1)" "unprognostic (1.65e-2)" "unprognostic (1.37e-1)" "unprognostic (1.92e-1)" "unprognostic (9.69e-2)" "unprognostic (3.76e-3)" "unprognostic (1.90e-1)" "unprognostic (4.33e-6)" "unprognostic (3.89e-2)" "unprognostic (3.94e-1)" "unprognostic (3.29e-1)" "prognostic unfavorable (1.55e-5)" 21.0 0.3 0.0 8.6 0.0 36.5 8.7 0.0 1.3 21.0 0.0 0.5 0.1 0.7 0.0 239.1 8.4 0.7 1.0 0.0 0.2 0.2 0.3 2.8 0.0 0.0 0.1 0.3 1.1 0.2 0.1 50.1 0.0 0.2 0.0 0.0 31.2 0.0 0.3 89.2 0.1 1.7 0.0 0.3 0.8 0.0 1.1 2.6 0.1 0.2 81.2 6.6 45.4 0.0 1.4 0.0 0.0 0.8 1.3 0.6 0.2 169.2 179.2 6.0 13.1 0.9 0.4 0.2 0.0 6.1 282.7 699.1 0.0 143.7 118.6 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.5 1.5 13.9 81.7 37.0 1.8 0.6 0.0 0.6 0.4 2.8 0.0 0.2 0.4 0.3 0.2 1.8 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.6 1.1 0.0 0.6 0.7 15.7 13.9 807.0 0.4 1243.9 0.0 0.2 0.1 0.0 21.6 1.8 96.7 22.0 4.9 10.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 1.3 0.0 0.0 0.0 1.3 0.0 0.2 0.0 0.1 0.0 0.0 1.1 0.0 0.2 0.0 0.5 0.0 0.2 2243.9 4.1 82.1 0.0 0.0 0.6 0.1 0.7 0.0 153.4 0.0 0.0 6.2 0.1 0.0 0.0 92.6 0.0 0.1 0.1 5.5 0.0 0.0 0.0 7.1 1.7 11.0 0.0 0.3 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 26.4 2.9 86.4 0.0 0.0 73.1 94.3 0.0 3.9 0.0 0.0 0.0 0.0 167.2 0.0 0.0 1.0 18.9 0.0 0.0 94.5 0.0 0.0 0.3 14.8 0.0 0.0 94.7 1053.6 439.3 2.5 0.0 0.0 52.0 SERPINF2 "A2AP, AAP, ALPHA-2-PI, API, PLI" ENSG00000167711 "Serpin family F member 2" P08697 17 1742836-1755265 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Acute phase" "Protease inhibitor, Serine protease inhibitor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 16 "liver: 1578.5" "Cell type enriched" "Detected in many" 11 "Hepatocytes: 1007.7" "Cancer enriched" "Detected in all" 6 "liver cancer: 450.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "plasmacytoid DC: 44.7" "Lineage enriched" "Detected in many" 23 "dendritic cells: 44.7" "Cell line enriched" "Detected in some" 24 "Hep G2: 145.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA001885, CAB024863" Approved "Secreted to blood" NA NA 11900 61000000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "CAB024863: , HPA001885: AB_1079922" "unprognostic (2.17e-3)" "unprognostic (2.56e-3)" "unprognostic (2.48e-1)" "unprognostic (7.57e-3)" "unprognostic (3.69e-2)" "unprognostic (1.45e-2)" "prognostic favorable (2.26e-5)" "unprognostic (1.44e-1)" "unprognostic (2.32e-2)" "unprognostic (1.38e-1)" "unprognostic (1.88e-3)" "unprognostic (2.18e-1)" "unprognostic (1.09e-3)" "unprognostic (7.05e-2)" "unprognostic (2.81e-1)" "unprognostic (7.68e-3)" "unprognostic (2.93e-1)" 11.6 2.0 1.4 4.3 1.5 0.4 18.3 1.2 2.2 7.1 11.1 4.2 0.7 8.7 101.4 3.0 19.6 0.7 2.5 2.0 1.4 74.1 1578.5 12.9 3.0 1.6 1.6 7.7 9.2 0.1 1.9 0.8 1.7 21.4 0.5 0.5 6.1 32.6 4.3 5.5 11.6 1.8 1.3 7.1 3.7 12.5 1.8 2.6 7.9 0.4 3.5 7.3 5.8 2.2 1.8 6.1 0.0 0.0 0.5 0.3 0.3 0.0 0.0 0.0 0.0 0.0 3.8 0.3 0.9 0.0 0.3 0.9 0.0 3.3 0.0 0.0 0.0 0.1 0.9 145.9 1.1 0.8 0.1 1.6 1.2 0.0 0.7 0.1 0.0 0.1 0.2 0.2 0.0 0.2 0.0 0.7 0.1 0.3 0.3 0.1 0.9 1.3 0.0 0.3 0.0 0.2 0.6 0.0 1.1 0.0 0.2 0.1 0.3 0.0 0.6 0.1 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 1.9 1.4 0.0 0.8 0.0 0.5 0.0 0.0 10.7 0.5 0.0 0.0 0.0 1.2 0.0 44.7 0.0 1.2 1.4 1.5 1.2 2.2 2.0 1.4 1.6 1.6 1.7 1.3 1.8 2.2 1.6 3.2 19.6 0.3 5.3 1.5 4.9 10.3 8.0 0.2 20.5 8.8 0.7 27.1 7.0 1.8 6.2 0.2 32.1 0.7 9.8 0.0 0.6 0.1 2.7 3.4 4.2 23.6 1.6 4.9 0.3 2.7 0.0 0.3 1.3 0.3 14.6 1007.7 7.7 0.0 1.9 2.1 12.2 32.2 20.1 0.8 33.8 8.2 1.8 1.0 10.9 0.1 0.0 1.0 0.7 3.8 2.7 26.7 3.2 2.8 2.2 87.5 4.4 0.4 0.0 1.3 1.2 0.4 0.5 1.3 1.6 0.3 2.6 0.0 3.3 1.8 SF3B3 "KIAA0017, RSE1, SAP130, SF3b130" ENSG00000189091 "Splicing factor 3b subunit 3" Q15393 16 70523791-70577670 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041134, HPA042986" Supported Supported "Nucleoplasm,Nucleoli,Nucleoli rim" No No 50000 "Cluster 39: Non-specific - mRNA processing" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Nucleoli, Nucleoli rim" "HPA041134: AB_2677317, HPA042986: AB_10960386" "unprognostic (3.39e-2)" "unprognostic (1.53e-1)" "unprognostic (7.47e-2)" "unprognostic (1.87e-1)" "unprognostic (2.05e-2)" "unprognostic (3.59e-2)" "unprognostic (1.06e-2)" "unprognostic (7.67e-2)" "unprognostic (2.07e-1)" "unprognostic (2.29e-1)" "unprognostic (6.97e-2)" "unprognostic (2.29e-1)" "unprognostic (3.28e-2)" "unprognostic (1.60e-1)" "unprognostic (8.76e-2)" "unprognostic (7.91e-2)" "unprognostic (1.73e-1)" 15.7 11.2 7.9 19.2 8.2 22.2 13.8 15.9 9.6 16.3 11.4 17.1 13.6 17.0 10.2 19.9 16.4 11.6 12.1 8.8 9.7 12.5 12.3 11.7 24.3 7.0 6.9 22.3 13.8 16.8 7.9 14.1 7.5 11.6 13.2 16.3 12.6 10.7 23.6 19.9 12.9 16.0 6.5 13.9 13.2 10.2 10.4 23.7 14.5 11.7 26.6 14.2 14.4 12.0 72.4 72.6 93.4 65.3 45.5 41.6 74.0 66.3 55.5 84.5 67.3 75.6 55.8 97.1 52.6 51.8 49.9 81.4 98.0 55.7 133.0 31.5 71.1 75.1 56.7 81.0 30.6 106.1 83.9 39.8 40.1 93.9 68.8 54.1 50.9 55.3 104.6 34.2 67.4 87.5 92.9 51.6 85.2 44.8 41.9 163.2 73.3 109.7 26.9 96.4 81.4 59.8 217.7 33.8 33.8 39.2 73.9 53.0 52.7 61.9 67.8 49.2 71.6 37.4 90.4 260.7 40.9 66.9 61.3 23.4 26.1 28.1 35.8 30.8 39.3 28.4 33.1 37.5 35.3 34.3 38.8 33.7 8.3 35.5 31.2 19.1 40.2 37.4 7.9 8.2 15.9 9.6 8.8 9.7 7.0 6.9 7.5 6.5 10.4 12.0 18.9 25.6 25.7 16.6 33.0 22.4 23.2 23.4 13.1 35.5 20.5 18.3 29.3 14.3 25.4 23.9 14.6 33.6 21.6 19.7 7.9 20.7 6.3 17.8 31.9 25.4 21.1 36.8 23.2 23.2 34.7 24.2 20.4 17.5 17.7 52.3 17.5 23.6 23.6 40.4 26.5 21.8 24.4 20.6 12.8 10.3 33.8 19.2 17.8 24.4 22.7 19.4 25.7 26.2 26.7 24.9 14.0 33.1 25.1 30.2 18.1 15.7 18.8 26.7 6.6 30.2 18.8 28.7 33.3 37.6 26.1 25.4 28.3 48.2 31.6 24.7 SFRP1 "FRP, FRP-1, SARP2" ENSG00000104332 "Secreted frizzled related protein 1" Q8N474 8 41261962-41309473 "Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "breast: 299.3;choroid plexus: 509.2" "Cell type enhanced" "Detected in many" "Breast glandular cells: 710.9;Breast myoepithelial cells: 1158.6;Cardiomyocytes: 266.3;Leydig cells: 578.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "hTERT-RPE1: 3203.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008116, HPA064870" Approved Approved Nucleoli,Cytosol "Secreted in other tissues" Yes No 1300000 "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 35: Glandular cells - Unknown function" Nucleoli Cytosol "CAB008116: AB_2187070, HPA064870: AB_2685376" "unprognostic (1.23e-3)" "unprognostic (7.01e-2)" "unprognostic (2.14e-1)" "unprognostic (3.59e-1)" "unprognostic (7.13e-2)" "prognostic favorable (1.55e-4)" "unprognostic (1.79e-1)" "unprognostic (2.69e-3)" "unprognostic (2.15e-2)" "unprognostic (4.67e-3)" "unprognostic (3.52e-3)" "unprognostic (4.74e-2)" "unprognostic (1.72e-2)" "unprognostic (1.75e-2)" "unprognostic (1.28e-1)" "unprognostic (2.57e-1)" "prognostic unfavorable (3.12e-4)" 88.4 12.9 9.2 10.5 12.7 1.4 299.3 18.2 15.0 203.7 509.2 24.5 12.2 132.5 1.8 26.1 98.5 61.3 124.8 29.4 8.5 115.3 6.1 4.7 4.0 29.9 10.5 46.8 6.2 1.4 1.2 19.5 29.7 42.6 30.1 2.2 236.9 102.3 2.6 55.4 18.9 82.9 7.7 21.4 24.4 28.4 10.8 3.1 12.7 32.8 3.2 44.9 95.6 24.7 0.1 29.0 75.9 1.9 67.5 3.9 14.5 132.9 694.5 197.9 187.2 0.0 17.8 0.0 0.6 0.7 15.8 0.9 10.8 53.7 277.6 0.0 2.3 0.0 0.0 0.0 6.4 0.0 0.7 11.8 255.9 19.9 19.3 3203.5 6.2 0.2 0.0 0.0 3.7 0.0 0.0 0.2 205.8 0.1 0.3 0.0 15.7 0.0 422.6 0.0 4.1 18.5 5.5 0.0 41.5 264.7 0.1 2.1 1.9 0.1 19.6 0.2 18.3 0.0 0.0 0.0 0.2 0.0 279.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 12.7 18.2 15.0 29.4 8.5 29.9 10.5 29.7 7.7 10.8 24.7 8.4 0.0 0.0 2.0 1.2 11.2 134.0 1.4 147.4 1.8 710.9 1158.6 266.3 0.0 0.7 62.5 2.1 2.2 9.1 0.0 80.3 4.4 5.0 3.0 131.6 21.0 0.0 0.0 0.2 0.0 82.0 229.5 16.8 3.4 0.0 19.3 53.6 0.3 2.0 1.7 12.1 0.0 0.0 0.3 4.0 25.7 578.4 4.0 99.6 0.0 0.0 76.2 0.0 7.5 20.6 0.1 0.0 130.1 2.1 29.7 0.0 3.2 0.0 1.8 0.0 34.9 18.0 2.3 16.8 53.7 5.5 0.8 7.3 72.6 0.0 9.3 SFRP2 "FRP-2, SARP1, SDF-5" ENSG00000145423 "Secreted frizzled related protein 2" Q96HF1 4 153780591-153789083 "Predicted secreted proteins" "Differentiation, Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 318.8;urinary bladder: 306.7" "Cell type enriched" "Detected in many" 4 "Fibroblasts: 806.1" "Cancer enhanced" "Detected in all" "pancreatic cancer: 370.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "AF22: 229.1;ASC diff: 85.2;HSkMC: 140.2;NTERA-2: 318.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA002652 Approved "Intermediate filaments" "Secreted in other tissues" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Intermediate filaments" "HPA002652: AB_2732394" "unprognostic (2.63e-1)" "unprognostic (2.47e-1)" "unprognostic (7.21e-3)" "unprognostic (1.80e-2)" "unprognostic (2.73e-1)" "unprognostic (8.80e-3)" "unprognostic (5.71e-3)" "unprognostic (2.62e-2)" "unprognostic (2.79e-1)" "unprognostic (7.47e-3)" "unprognostic (1.44e-2)" "unprognostic (5.29e-2)" "prognostic unfavorable (8.56e-6)" "unprognostic (9.29e-3)" "unprognostic (4.72e-2)" "unprognostic (1.05e-2)" "prognostic unfavorable (4.39e-4)" 188.2 16.0 4.9 84.6 4.0 0.3 154.9 3.6 6.3 23.2 11.2 72.2 18.4 12.0 22.2 212.7 62.1 318.8 6.2 12.3 13.8 4.5 0.3 62.5 11.8 4.5 3.7 8.3 45.1 7.0 72.5 0.4 4.6 56.5 44.3 2.3 83.4 70.5 6.5 80.5 57.3 89.5 3.8 0.7 34.4 1.5 2.2 9.6 92.3 38.7 3.6 306.7 63.0 12.3 0.0 0.0 229.1 0.2 85.2 15.1 0.1 0.2 0.3 0.0 0.0 0.0 0.2 0.0 0.1 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 140.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 318.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 6.1 0.1 0.1 0.0 8.1 0.2 0.0 0.0 0.4 0.1 0.0 12.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 4.0 3.6 6.3 12.3 13.8 4.5 3.7 4.6 3.8 2.2 12.3 15.5 3.2 0.6 9.4 0.5 115.5 0.8 0.0 5.7 0.0 3.7 7.9 0.3 0.0 1.9 0.0 0.0 0.1 2.0 0.0 0.0 0.2 0.0 0.1 0.1 11.8 0.0 0.0 0.7 0.0 0.2 806.1 38.7 0.3 1.3 0.0 0.0 0.0 4.4 0.0 0.6 0.0 0.0 0.0 175.0 0.5 4.1 5.0 119.2 0.0 0.6 0.0 0.0 0.5 0.1 0.1 0.0 7.2 4.1 0.7 0.0 0.1 2.9 0.0 0.0 6.7 59.4 0.0 0.1 6.9 106.0 0.1 8.6 0.0 0.0 0.9 SGIP1 DKFZp761D221 ENSG00000118473 "SH3GL interacting endocytic adaptor 1" Q9BQI5 1 66533383-66751139 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "retina: 131.4" "Group enriched" "Detected in many" 4 "Astrocytes: 390.1;Cone photoreceptor cells: 350.3;Excitatory neurons: 323.3;Inhibitory neurons: 401.5;Oligodendrocyte precursor cells: 482.0;Oligodendrocytes: 363.6;Rod photoreceptor cells: 344.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 29.9;BJ hTERT+: 38.0;fHDF/TERT166: 24.5;hTERT-RPE1: 15.8;RPTEC TERT1: 27.5;SH-SY5Y: 15.3;U-138 MG: 27.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017963 Approved Approved Mitochondria NA NA "Cluster 77: Retina - Visual perception" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 9: Photoreceptor cells - Phototransduction" Mitochondria "HPA017963: AB_10964882" "unprognostic (1.74e-2)" "unprognostic (2.77e-1)" "unprognostic (2.86e-1)" "unprognostic (1.07e-1)" "unprognostic (1.74e-1)" "unprognostic (9.04e-2)" "unprognostic (9.51e-2)" "unprognostic (7.64e-2)" "unprognostic (1.86e-1)" "unprognostic (1.61e-1)" "unprognostic (1.83e-1)" "unprognostic (1.95e-1)" "unprognostic (3.48e-7)" "unprognostic (1.77e-2)" "unprognostic (1.29e-1)" "unprognostic (4.25e-2)" "unprognostic (9.63e-2)" 7.4 4.3 12.2 1.9 15.5 0.2 2.7 6.3 17.4 10.4 0.0 3.1 1.6 10.6 4.6 2.7 3.8 4.6 5.0 15.3 5.8 18.0 0.7 8.3 0.7 5.1 5.7 1.6 0.5 0.2 7.7 1.9 5.3 5.8 1.5 131.4 1.7 5.0 2.5 1.6 2.0 3.8 1.6 0.3 3.3 4.4 5.5 0.7 8.9 1.2 0.4 2.7 5.4 10.1 0.0 0.0 0.0 0.0 0.9 5.5 0.0 29.9 38.0 2.3 3.4 0.0 0.0 0.0 0.1 24.5 0.2 0.0 0.0 0.1 4.3 0.0 0.0 1.1 0.4 0.0 6.5 0.0 0.0 4.1 0.0 2.3 0.0 15.8 11.3 0.2 0.0 0.0 13.8 0.0 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.1 27.5 0.0 0.7 15.3 0.0 0.0 0.0 0.6 0.0 1.1 1.9 27.3 0.0 0.7 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.2 15.5 6.3 17.4 15.3 5.8 5.1 5.7 5.3 1.6 5.5 10.1 5.0 0.0 0.0 390.1 0.1 1.0 0.3 0.4 0.0 89.8 0.2 4.7 2.5 2.8 0.0 9.2 350.3 0.1 0.0 0.1 7.9 0.5 0.6 2.9 7.8 13.8 0.0 0.0 323.3 0.0 0.0 15.8 0.5 5.7 10.1 0.0 0.4 0.2 0.2 74.0 401.5 0.0 0.0 0.0 1.1 1.2 2.1 0.4 10.6 48.7 0.0 49.4 0.0 482.0 363.6 0.0 0.0 11.3 0.8 0.8 0.0 0.2 0.0 344.1 13.1 3.2 32.2 0.2 0.4 0.1 1.0 0.3 0.5 0.0 0.1 0.3 SGPL1 SPL ENSG00000166224 "Sphingosine-1-phosphate lyase 1" O95470 10 70815948-70881184 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Lipid metabolism, Sphingolipid metabolism" Lyase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RT4: 112.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021125, HPA023086" Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 37: Intestine - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" "Endoplasmic reticulum" "HPA021125: AB_1856803, HPA023086: AB_1856804" "unprognostic (1.14e-1)" "unprognostic (1.77e-1)" "unprognostic (1.15e-1)" "unprognostic (3.07e-2)" "unprognostic (2.13e-1)" "unprognostic (2.34e-1)" "unprognostic (7.60e-2)" "unprognostic (2.98e-2)" "unprognostic (2.88e-1)" "unprognostic (1.06e-1)" "unprognostic (1.70e-2)" "unprognostic (2.12e-1)" "unprognostic (9.52e-2)" "unprognostic (3.42e-1)" "unprognostic (2.14e-1)" "unprognostic (9.21e-2)" "unprognostic (4.68e-3)" 12.0 12.7 15.8 18.0 17.4 6.8 13.0 15.2 16.3 17.6 11.0 16.7 16.0 14.4 18.8 27.9 15.3 12.6 6.4 14.7 16.4 15.5 22.9 10.7 18.1 18.6 16.7 9.0 18.5 21.0 9.4 10.0 17.4 17.5 17.9 10.8 14.3 12.4 9.6 30.4 22.8 13.9 17.4 16.1 12.3 14.0 17.7 17.9 20.1 6.0 20.1 25.0 14.7 19.8 26.9 35.2 33.2 38.1 8.9 11.5 22.1 15.5 16.4 16.5 21.4 38.4 57.8 24.2 18.0 15.8 15.9 44.1 28.8 31.0 23.5 39.1 15.6 2.5 17.5 46.2 33.6 10.6 20.9 21.8 51.4 22.1 57.6 34.6 10.4 22.3 7.2 20.4 23.6 29.6 13.2 7.1 15.0 35.4 19.5 16.6 25.2 9.1 26.3 112.1 22.6 27.5 30.9 46.6 28.5 25.9 24.3 7.5 20.3 14.8 38.7 11.6 30.1 8.4 12.6 11.0 14.7 19.3 10.7 1.1 18.2 14.0 18.0 34.6 16.5 7.2 11.5 14.7 16.2 8.7 8.5 13.5 15.0 18.8 44.9 8.9 11.8 12.4 15.8 17.4 15.2 16.3 14.7 16.4 18.6 16.7 17.4 17.4 17.7 19.8 3.8 16.0 6.4 32.3 11.0 12.2 17.8 21.4 8.0 6.3 15.8 9.8 6.3 27.1 23.2 46.0 20.9 7.3 16.0 41.5 3.9 36.2 2.9 30.2 13.3 7.3 25.1 4.4 48.7 37.6 13.8 10.1 6.6 46.1 14.7 23.1 7.1 44.5 27.6 15.2 38.8 21.2 22.4 43.1 16.1 5.2 11.5 25.7 7.2 35.6 22.7 9.8 25.7 41.7 43.8 55.6 18.8 20.3 5.9 26.0 53.5 12.0 26.6 9.7 6.6 13.3 19.0 20.0 34.0 15.9 22.7 6.3 11.1 18.2 20.9 25.3 SH3BP1 ARHGAP43 ENSG00000100092 "SH3 domain binding protein 1" Q9Y3L3 22 37634654-37656117 "Metabolic proteins, Predicted intracellular proteins" Phagocytosis "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 37.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HaCaT: 43.5;HMC-1: 45.4;NB-4: 44.7" "Low region specificity" "Detected in all" HPA000757 Supported Approved Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "HPA000757: AB_1079951" "unprognostic (7.81e-3)" "unprognostic (7.91e-3)" "unprognostic (3.42e-1)" "unprognostic (2.62e-2)" "unprognostic (5.38e-2)" "unprognostic (2.40e-1)" "prognostic unfavorable (9.55e-4)" "unprognostic (1.39e-1)" "unprognostic (3.08e-1)" "unprognostic (1.89e-1)" "unprognostic (2.59e-2)" "unprognostic (4.78e-1)" "prognostic unfavorable (3.48e-7)" "prognostic favorable (3.39e-4)" "unprognostic (1.74e-1)" "unprognostic (5.37e-2)" "unprognostic (8.48e-3)" 4.2 3.6 3.4 14.2 3.4 14.4 3.4 3.7 6.2 12.2 2.7 19.4 18.1 3.2 0.7 37.7 4.0 2.1 2.0 4.1 4.5 3.2 2.6 8.8 12.1 6.0 3.9 3.4 2.8 2.2 2.1 5.1 4.7 7.6 4.5 0.2 9.3 2.0 0.7 27.0 20.9 2.0 4.8 27.0 4.3 5.7 4.7 8.2 2.5 0.5 7.7 10.5 21.1 5.7 20.1 1.0 3.9 3.4 0.9 3.9 28.6 3.8 6.4 6.3 7.0 5.9 2.3 12.6 2.7 2.4 2.0 43.5 2.0 26.0 2.6 36.9 13.7 18.5 0.6 8.6 3.3 25.9 45.4 4.9 6.3 7.9 0.9 5.2 1.0 6.3 6.4 4.8 0.6 12.7 3.0 44.7 7.6 13.7 3.8 15.7 3.2 11.0 0.8 22.2 3.8 10.1 1.0 5.3 17.9 3.9 6.7 22.1 1.3 2.3 10.8 0.5 0.2 29.9 10.2 9.0 3.2 26.4 13.0 1.8 1.4 4.6 1.0 1.8 1.0 0.3 1.1 1.1 0.7 0.1 0.6 1.4 0.9 0.8 3.7 1.2 1.1 0.6 3.4 3.4 3.7 6.2 4.1 4.5 6.0 3.9 4.7 4.8 4.7 5.7 1.2 0.0 7.2 0.7 23.7 19.1 22.2 42.5 23.3 0.3 3.3 4.1 1.2 4.3 8.0 0.0 2.1 47.5 36.1 55.0 0.0 3.0 0.4 0.6 4.3 1.7 4.2 7.8 5.6 4.7 43.9 6.0 11.2 1.3 14.0 3.4 4.2 0.5 48.3 8.4 0.8 29.9 12.2 33.3 19.0 0.1 5.0 45.6 5.4 2.8 36.0 3.0 53.5 5.0 0.9 2.0 46.8 1.9 20.9 29.6 41.9 0.3 11.4 0.5 0.0 0.9 3.6 3.4 6.0 23.6 15.3 37.5 52.7 5.0 23.6 42.0 SH3RF2 "FLJ23654, Hepp1, POSHER, PPP1R39, RNF158" ENSG00000156463 "SH3 domain containing ring finger 2" Q8TEC5 5 145936578-146081791 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Protein phosphatase inhibitor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 58.1;skeletal muscle: 42.4;skin 1: 56.8" "Cell type enriched" "Detected in many" 5 "Late spermatids: 7869.1" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 4 "basal ganglia: 6.1;cerebral cortex: 4.1;thalamus: 1.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 70.3;GAMG: 29.8;hTERT-RPE1: 33.5" "Region enriched" "Detected in many" 14 "basal ganglia: 26.7" "Region enhanced" "Detected in many" "basal ganglia: 9.7" "HPA035903, HPA058119" Uncertain Enhanced Nucleoplasm NA Yes "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 31: Skin - Epidermis development" "Cluster 39: CACO-2 - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "HPA035903: AB_10696515, HPA058119: AB_2683611" "unprognostic (8.90e-3)" "unprognostic (2.00e-3)" "unprognostic (5.11e-3)" "unprognostic (1.66e-2)" "unprognostic (1.45e-3)" "unprognostic (1.47e-2)" "unprognostic (9.96e-3)" "unprognostic (8.22e-2)" "unprognostic (3.92e-1)" "unprognostic (7.37e-3)" "unprognostic (2.44e-3)" "unprognostic (1.66e-1)" "unprognostic (2.98e-2)" "unprognostic (5.21e-2)" "unprognostic (1.46e-1)" "unprognostic (2.64e-2)" "unprognostic (4.13e-3)" 1.9 0.9 0.6 2.5 6.1 0.0 4.7 0.0 4.1 7.6 0.2 14.3 16.0 1.1 3.6 34.1 6.1 11.9 58.1 0.9 0.5 0.9 7.0 2.7 0.2 0.0 0.3 0.4 15.4 0.0 1.6 0.1 0.0 2.7 14.3 0.5 12.1 0.6 42.4 56.8 13.7 1.1 0.0 0.0 20.5 6.8 1.7 1.0 6.3 8.8 7.7 1.2 20.6 0.4 21.0 5.7 0.2 1.1 0.0 0.0 0.0 0.2 1.7 4.1 1.7 70.3 19.0 0.0 10.5 0.9 29.8 18.9 0.0 22.4 4.0 0.3 0.3 0.0 8.5 9.5 1.2 0.0 0.0 0.2 11.9 6.4 14.8 33.5 0.2 0.5 0.0 0.0 1.8 0.1 0.0 0.0 1.6 17.3 1.5 0.0 0.2 0.0 8.7 2.0 0.0 0.0 1.2 0.4 0.5 1.0 6.6 0.1 9.8 0.8 17.3 1.5 6.7 0.0 0.0 0.0 10.6 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.6 6.1 0.0 4.1 0.9 0.5 0.0 0.3 0.0 0.0 1.7 0.4 4.1 16.0 2.3 1.6 0.0 55.1 5.4 14.5 38.7 0.4 3.9 3.3 510.0 8.6 6.7 1.8 0.0 0.2 0.2 38.9 0.0 5.7 1511.3 11.9 0.9 9.7 1.2 0.0 10.5 8.7 0.0 15.4 50.4 26.7 1.3 0.1 0.7 8.4 0.2 0.0 2.2 16.1 8.2 0.0 4.9 7869.1 25.7 2.6 8.8 10.3 0.6 1.6 0.0 1.5 0.7 21.4 22.9 34.6 0.6 2.2 26.6 0.9 4.4 0.1 13.1 1.6 6.3 31.4 20.7 70.9 50.0 0.0 0.7 2.9 33.2 6.6 SH3TC2 "CMT4C, KIAA1985" ENSG00000169247 "SH3 domain and tetratricopeptide repeats 2" Q8TF17 5 148923639-149063163 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 12.6;retina: 3.9" "Cell type enriched" "Detected in many" 10 "Oligodendrocytes: 270.4" "Cancer enhanced" "Detected in some" "melanoma: 1.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 2.6;HBEC3-KT: 2.2;RT4: 3.6;SK-MEL-30: 5.2;WM-115: 3.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA037683, HPA037684" Uncertain Approved Nucleoplasm,Cytosol No No "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Cytosol" "HPA037683: AB_2675608, HPA037684: AB_10672603" "unprognostic (6.30e-2)" "unprognostic (4.07e-2)" "unprognostic (4.22e-2)" "unprognostic (5.52e-2)" "unprognostic (1.70e-1)" "unprognostic (1.92e-2)" "unprognostic (2.49e-1)" "unprognostic (2.17e-4)" "unprognostic (2.18e-2)" "unprognostic (4.53e-1)" "unprognostic (6.21e-3)" "unprognostic (2.20e-1)" "unprognostic (2.21e-1)" "unprognostic (6.48e-2)" "unprognostic (1.84e-1)" "unprognostic (6.62e-2)" "unprognostic (1.40e-1)" 0.1 0.0 4.7 0.0 8.0 0.1 0.1 5.1 5.0 0.1 0.4 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.3 3.6 5.1 0.0 0.0 0.0 0.0 7.1 6.9 0.0 0.0 0.0 0.0 0.4 7.3 0.0 0.0 3.9 0.1 0.1 0.2 0.1 0.0 0.0 5.8 0.0 0.0 1.5 7.1 0.0 0.0 0.1 0.0 0.1 0.0 12.6 1.8 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.3 0.1 2.6 1.5 0.0 1.8 0.1 0.6 1.9 0.0 2.2 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.4 0.2 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 1.1 1.6 0.0 1.3 0.0 0.7 3.6 0.0 0.0 0.0 0.0 5.2 0.1 0.0 0.0 0.2 0.1 0.3 0.0 1.0 0.0 0.0 0.0 0.0 0.4 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 8.0 5.1 5.0 3.6 5.1 7.1 6.9 7.3 5.8 7.1 12.6 1.9 3.2 3.7 0.3 0.1 0.9 0.8 1.0 0.0 1.4 0.7 0.4 1.7 1.5 3.8 0.0 4.2 0.8 0.0 0.6 0.0 0.6 6.4 0.3 0.1 2.8 0.0 0.0 0.4 0.2 0.4 0.5 0.0 0.5 2.5 0.1 1.4 0.3 0.4 0.0 0.4 0.0 2.0 1.8 0.7 2.3 0.3 2.2 0.0 4.7 0.1 2.3 0.0 0.0 270.4 1.6 0.0 0.0 0.1 1.2 0.0 0.1 4.1 25.4 0.0 0.3 0.4 2.3 0.9 1.0 0.9 11.9 0.3 0.1 0.2 8.8 SHANK2 "CORTBP1, CTTNBP1, ProSAP1, SHANK, SPANK-3" ENSG00000162105 "SH3 and multiple ankyrin repeat domains 2" Q9UPX8 11 70467854-71252577 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Autism, Autism spectrum disorder" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 31.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 153.5;Horizontal cells: 136.3;Inhibitory neurons: 167.5" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 8 "amygdala: 7.7;basal ganglia: 7.5;cerebral cortex: 9.3;hippocampal formation: 9.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 11.5;Karpas-707: 17.5;RT4: 15.9;T-47d: 16.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008174, HPA017220" Approved Approved "Nuclear speckles,Vesicles,Plasma membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Vesicles, Plasma membrane" "Nuclear speckles" "HPA008174: AB_1856822, HPA017220: " "unprognostic (3.08e-1)" "unprognostic (1.31e-3)" "unprognostic (1.79e-1)" "unprognostic (1.51e-2)" "unprognostic (1.51e-1)" "unprognostic (7.23e-5)" "unprognostic (1.24e-1)" "unprognostic (6.67e-2)" "unprognostic (1.83e-2)" "unprognostic (8.42e-2)" "unprognostic (4.87e-2)" "unprognostic (4.01e-1)" "prognostic favorable (1.94e-6)" "unprognostic (3.46e-2)" "unprognostic (2.34e-1)" "unprognostic (4.03e-2)" "unprognostic (4.80e-2)" 1.3 1.2 7.7 0.5 7.5 0.0 4.5 0.2 9.3 1.3 31.7 2.4 1.5 1.0 2.2 3.4 5.1 0.8 0.0 9.5 0.0 4.9 3.8 3.7 0.1 0.0 0.0 0.1 7.5 0.1 2.2 1.9 0.0 3.2 2.0 5.5 9.8 1.8 0.0 0.9 1.3 0.4 0.0 1.1 3.0 0.9 1.0 0.0 6.0 0.0 0.4 1.1 0.3 0.9 0.5 7.4 4.1 0.0 0.6 0.4 4.5 0.7 0.3 0.0 0.0 6.6 3.1 6.2 2.2 0.0 0.1 1.1 0.0 4.8 0.0 0.0 0.2 0.0 0.0 11.5 0.0 0.0 1.9 0.1 1.8 0.0 0.0 1.6 0.0 0.1 0.0 17.5 1.7 10.5 0.0 0.1 3.5 10.2 0.3 0.0 9.9 8.2 5.2 15.9 3.5 1.1 0.0 8.4 0.0 5.2 16.4 0.0 0.0 0.0 1.5 0.1 0.0 0.1 0.6 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 7.5 0.2 9.3 9.5 0.0 0.0 0.0 0.0 0.0 1.0 0.9 8.0 41.7 17.0 21.5 0.2 0.0 3.2 3.2 0.6 17.9 26.9 13.0 3.7 11.5 5.4 7.3 0.0 12.8 0.4 3.2 3.9 8.4 1.7 30.0 3.2 1.3 0.0 0.0 153.5 2.2 2.9 1.8 10.2 13.0 2.5 1.2 0.4 21.9 1.2 136.3 167.5 7.9 8.2 0.0 0.3 2.1 0.0 0.4 5.4 14.0 0.0 4.6 0.0 41.7 5.3 10.7 2.7 0.7 0.4 10.9 0.6 10.8 23.3 1.0 0.0 0.3 1.3 0.7 0.9 1.3 0.6 14.6 0.3 0.1 5.5 4.0 SHF ENSG00000138606 "Src homology 2 domain containing F" Q7M4L6 15 45167214-45201175 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 143.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 50.6;Granulosa cells: 58.8" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 143.8" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SCLC-21H: 121.0;SH-SY5Y: 54.1" "Region enriched" "Detected in all" 5 "cerebellum: 240.6" "Region enriched" "Detected in all" 4 "cerebellum: 106.2" HPA057381 Approved Nucleoplasm NA NA "Cluster 24: B-cells - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA057381: AB_2683423" "unprognostic (4.05e-2)" "unprognostic (2.02e-3)" "unprognostic (7.59e-2)" "unprognostic (1.54e-1)" "unprognostic (1.88e-2)" "unprognostic (2.18e-1)" "unprognostic (2.38e-1)" "unprognostic (7.61e-2)" "unprognostic (2.18e-1)" "unprognostic (3.50e-2)" "unprognostic (6.88e-2)" "unprognostic (5.12e-2)" "unprognostic (6.89e-2)" "unprognostic (2.83e-2)" "unprognostic (1.17e-1)" "unprognostic (5.09e-3)" "unprognostic (1.83e-2)" 6.1 22.7 21.9 4.3 20.5 1.0 6.3 143.8 27.8 14.4 0.2 13.4 13.1 11.9 4.7 5.0 10.5 6.6 9.0 21.5 19.5 4.4 38.6 5.6 2.7 12.8 16.9 23.7 3.1 4.4 8.3 1.9 15.9 10.1 5.3 7.1 6.7 5.9 3.8 12.7 8.4 7.5 9.4 4.3 6.7 8.4 21.4 2.4 7.5 4.7 1.9 10.2 11.7 13.4 0.1 1.4 24.0 0.7 1.8 0.9 11.2 3.0 2.1 6.7 9.5 3.6 11.6 1.3 9.5 4.2 6.6 2.1 9.2 0.7 3.2 2.2 4.2 0.8 2.2 24.8 1.0 0.1 8.0 2.2 0.6 0.9 0.2 5.0 5.2 12.0 5.0 0.5 9.5 4.1 5.5 0.9 9.6 4.5 0.6 15.0 19.1 0.5 2.3 0.5 121.0 54.1 0.7 0.8 0.4 7.4 1.2 2.4 0.3 0.8 10.0 0.7 0.4 1.1 0.9 1.1 0.3 0.6 3.8 0.1 0.6 0.5 1.3 0.6 1.4 0.8 0.5 0.8 0.6 1.5 0.7 0.5 0.8 2.0 0.6 0.9 0.1 0.5 21.9 20.5 143.8 27.8 21.5 19.5 12.8 16.9 15.9 9.4 21.4 13.4 4.1 0.0 0.6 3.3 4.2 3.6 5.8 1.7 0.0 50.6 3.6 5.5 2.8 0.0 1.3 0.0 0.0 1.1 2.6 2.1 0.0 0.8 7.9 1.1 3.5 5.7 13.1 0.0 5.9 1.3 0.5 5.8 1.5 2.2 2.5 58.8 5.3 11.7 0.6 10.1 6.9 10.9 2.0 1.0 15.0 15.3 4.4 2.9 8.8 5.6 0.1 5.9 2.1 9.0 1.8 0.7 5.6 4.1 0.7 3.5 18.0 1.1 0.8 5.0 6.6 6.7 9.6 5.4 2.9 1.4 2.6 0.7 2.8 1.8 4.6 9.7 SHROOM1 "APXL2, KIAA1960" ENSG00000164403 "Shroom family member 1" Q2M3G4 5 132822141-132830659 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 116.9;prostate: 73.9;urinary bladder: 62.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 135.0;Hepatocytes: 79.2;Proximal enterocytes: 65.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RT4: 24.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037690, HPA037691" Uncertain Approved Vesicles NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA037690: AB_2675613, HPA037691: AB_2675614" "unprognostic (2.50e-1)" "unprognostic (1.06e-1)" "unprognostic (4.52e-2)" "unprognostic (2.66e-1)" "unprognostic (1.45e-2)" "unprognostic (3.47e-1)" "unprognostic (9.26e-2)" "unprognostic (1.33e-2)" "unprognostic (3.74e-1)" "unprognostic (3.24e-1)" "unprognostic (2.46e-2)" "unprognostic (1.01e-2)" "prognostic unfavorable (5.72e-6)" "unprognostic (8.22e-2)" "unprognostic (2.91e-2)" "unprognostic (2.88e-2)" "unprognostic (2.26e-3)" 9.3 2.4 25.2 2.6 32.0 0.2 8.2 28.9 26.9 12.6 10.4 20.5 6.1 11.3 2.1 5.1 8.4 6.7 7.6 20.2 23.6 10.7 116.9 10.5 0.6 42.1 30.9 5.6 16.2 4.9 6.8 11.8 33.3 73.9 11.1 3.4 7.0 15.2 1.7 1.5 16.6 3.9 26.1 2.3 10.9 1.7 31.2 0.6 6.9 1.3 0.5 62.4 9.3 55.7 8.6 5.1 0.9 0.8 1.4 4.0 9.0 9.1 7.7 7.0 7.8 11.2 5.7 1.5 12.5 4.9 3.8 0.8 3.1 5.7 4.3 9.5 11.0 0.3 8.7 10.5 4.1 0.7 3.1 1.7 3.0 4.9 3.0 4.8 4.8 0.1 7.3 8.1 6.1 4.8 0.2 4.0 1.4 6.7 8.1 0.5 0.0 0.8 1.2 24.4 5.7 1.5 8.8 0.7 4.9 4.5 5.2 2.9 4.5 8.1 11.7 1.1 11.5 9.2 6.8 0.1 7.9 0.0 2.5 0.2 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 25.2 32.0 28.9 26.9 20.2 23.6 42.1 30.9 33.3 26.1 31.2 55.7 18.3 25.6 22.3 18.9 1.8 1.3 15.4 2.3 3.4 3.7 9.3 5.5 2.2 30.0 11.3 9.2 10.4 6.8 1.0 135.0 1.9 6.0 0.9 7.1 17.3 18.1 22.8 2.7 3.0 10.7 4.8 6.1 33.6 15.1 8.2 9.0 25.0 79.2 6.6 16.8 1.0 28.6 0.0 8.7 5.5 1.1 4.7 4.6 0.0 23.4 8.1 19.9 3.1 6.6 37.5 7.1 53.6 4.9 3.6 31.6 65.5 3.5 9.1 13.3 26.3 2.8 5.1 7.6 5.1 1.8 2.0 2.9 2.5 1.4 35.5 17.3 SHROOM3 "APXL3, KIAA1481, SHRM, ShrmL" ENSG00000138771 "Shroom family member 3" Q8TF72 4 76435229-76783253 "Plasma proteins, Predicted intracellular proteins" "Cell shape" "Actin-binding, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 313.1;Distal enterocytes: 154.5;Endometrial ciliated cells: 182.9;Glandular and luminal cells: 350.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 40.8;AF22: 38.2;BJ hTERT+: 36.9;EFO-21: 39.9;OE19: 40.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA047784 Enhanced NA NA "Cluster 37: Intestine - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 44: Endometrium - Transcription" "HPA047784: AB_2680155" "unprognostic (1.96e-1)" "unprognostic (2.50e-1)" "unprognostic (1.57e-2)" "unprognostic (5.33e-2)" "unprognostic (1.61e-2)" "unprognostic (3.33e-2)" "unprognostic (7.96e-3)" "unprognostic (2.70e-2)" "unprognostic (1.92e-1)" "unprognostic (2.90e-1)" "unprognostic (1.45e-3)" "unprognostic (1.03e-1)" "prognostic favorable (1.64e-13)" "unprognostic (2.87e-2)" "unprognostic (2.25e-1)" "unprognostic (9.06e-2)" "unprognostic (1.87e-2)" 1.0 2.0 0.4 6.1 1.8 0.1 15.4 12.4 3.4 5.9 18.5 20.0 15.2 3.0 13.9 17.5 15.7 17.8 3.9 0.9 0.0 7.0 6.2 8.5 0.4 6.1 2.1 0.5 6.5 12.9 3.3 4.4 5.9 9.0 17.2 9.7 25.7 6.3 0.1 3.0 14.7 9.7 5.6 6.1 21.9 0.7 0.2 0.9 3.5 0.1 2.4 4.9 2.3 3.0 40.8 7.9 38.2 25.2 0.0 0.6 1.4 12.4 36.9 0.8 1.6 6.8 26.3 0.6 39.9 34.6 3.0 20.4 5.1 17.8 0.7 0.1 6.7 0.0 7.5 0.0 0.2 0.0 0.0 0.3 4.3 1.3 6.7 9.7 0.7 0.3 0.0 9.7 0.8 3.6 0.7 0.1 16.0 40.5 4.7 3.5 6.3 6.3 6.0 0.9 15.0 19.9 5.2 28.2 2.1 23.2 6.8 0.2 0.0 6.5 5.5 0.2 5.4 12.0 13.3 0.1 1.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.8 12.4 3.4 0.9 0.0 6.1 2.1 5.9 5.6 0.2 3.0 0.6 89.8 53.4 313.1 1.0 0.9 5.8 14.0 2.8 35.8 69.9 46.1 11.0 81.5 40.0 35.0 75.0 0.4 0.6 154.5 0.0 33.6 7.1 182.9 27.1 2.1 86.9 2.7 54.5 36.4 0.7 4.7 103.0 350.1 0.0 11.9 0.7 42.2 0.2 1.7 19.1 104.0 30.5 1.6 0.3 3.2 0.3 1.8 3.6 29.0 1.6 7.2 0.0 6.0 2.1 73.8 92.3 0.0 0.3 35.8 102.7 6.8 65.7 31.1 0.0 0.3 7.4 3.4 2.4 3.5 0.3 0.1 1.7 0.3 70.5 11.9 SHROOM4 KIAA1202 ENSG00000158352 "Shroom family member 4" Q9ULL8 X 50591642-50814302 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin-binding, Developmental protein" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.7" "Group enriched" "Detected in many" 5 "Oligodendrocyte precursor cells: 126.7;Oligodendrocytes: 463.4" "Cancer enhanced" "Detected in many" "thyroid cancer: 7.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 6.7;HUVEC TERT2: 26.7;RH-30: 5.0;RPTEC TERT1: 5.5;TIME: 10.0;WM-115: 5.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA010089, HPA010565" Uncertain Approved "Nucleoplasm,Vesicles,Focal adhesion sites" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Focal adhesion sites" "Nucleoplasm, Vesicles" "HPA010089: , HPA010565: AB_1079961" "unprognostic (2.55e-2)" "unprognostic (1.43e-1)" "unprognostic (5.56e-2)" "prognostic unfavorable (8.37e-4)" "unprognostic (1.34e-1)" "unprognostic (1.60e-2)" "unprognostic (4.30e-3)" "unprognostic (4.55e-2)" "unprognostic (2.13e-1)" "unprognostic (2.93e-1)" "unprognostic (1.52e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (4.66e-4)" "unprognostic (7.30e-2)" "unprognostic (2.83e-1)" "unprognostic (1.74e-2)" "unprognostic (2.75e-1)" 8.1 1.8 9.8 1.9 20.0 1.2 5.4 17.1 12.4 3.3 0.9 1.8 1.1 3.6 1.6 2.7 2.2 3.0 7.8 8.9 12.6 5.3 0.9 13.3 0.9 23.8 17.6 1.3 0.9 1.9 2.0 9.0 21.8 2.2 1.4 1.3 2.0 1.8 3.6 1.7 1.5 4.1 13.8 1.0 1.3 0.6 17.3 0.6 3.3 5.0 1.0 3.5 2.3 30.7 0.0 0.0 1.8 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.1 0.2 0.0 6.7 0.9 0.0 0.6 4.3 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.4 0.0 0.0 0.5 0.0 26.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 5.0 0.0 5.5 2.5 0.1 0.0 0.0 0.8 1.5 3.6 0.1 0.1 10.0 0.0 0.0 0.0 0.7 0.5 0.0 0.0 1.3 0.2 5.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 20.0 17.1 12.4 8.9 12.6 23.8 17.6 21.8 13.8 17.3 30.7 45.0 25.6 18.6 3.3 0.0 3.6 2.0 1.9 2.2 0.3 1.0 1.5 4.2 0.0 2.0 5.5 0.0 0.6 0.2 1.1 3.9 0.7 0.1 2.8 5.4 46.5 3.0 0.0 1.1 0.2 3.0 3.0 0.0 2.9 3.8 2.3 30.7 0.9 0.5 0.0 1.1 2.8 0.0 2.4 2.7 0.6 1.2 0.6 0.0 51.5 0.0 3.6 0.0 126.7 463.4 2.3 1.0 1.2 0.0 1.2 0.3 3.5 2.5 0.6 0.0 2.5 2.6 0.0 1.0 2.0 3.1 0.3 0.6 3.0 3.2 1.6 SIGLEC6 "CD327, CD33L, CD33L1, OB-BP1, SIGLEC-6" ENSG00000105492 "Sialic acid binding Ig like lectin 6" O43699 19 51517819-51531856 "CD markers, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 24 "placenta: 106.7" "Group enriched" "Detected in some" 13 "Cytotrophoblasts: 76.0;granulocytes: 55.0;Syncytiotrophoblasts: 188.7" "Cancer enhanced" "Detected in some" "thyroid cancer: 2.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "basophil: 4.9;memory B-cell: 7.2;naive B-cell: 4.5;plasmacytoid DC: 11.0" "Group enriched" "Detected in many" 13 "B-cells: 7.2;dendritic cells: 11.0;granulocytes: 4.9" "Cell line enriched" "Detected in some" 7 "HMC-1: 500.7" "HPA008945, HPA009084, HPA018198" Enhanced Approved "Plasma membrane,Cytosol" "Secreted to blood" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 3: HMC-1 - Innate immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane, Cytosol" "HPA008945: , HPA009084: AB_1079967, HPA018198: AB_1856868" "unprognostic (1.97e-1)" "unprognostic (1.41e-1)" "unprognostic (2.38e-3)" "unprognostic (9.31e-3)" "unprognostic (8.46e-4)" "unprognostic (2.91e-1)" "unprognostic (2.02e-2)" "unprognostic (2.64e-1)" "unprognostic (8.96e-2)" "unprognostic (2.03e-1)" "unprognostic (6.89e-2)" "unprognostic (1.10e-2)" "unprognostic (4.15e-2)" "unprognostic (4.42e-2)" "unprognostic (3.28e-2)" "unprognostic (5.57e-3)" 0.6 0.1 0.2 3.0 0.3 0.5 0.7 0.4 0.3 1.6 0.1 2.2 2.2 1.5 1.0 2.5 0.3 2.5 0.4 0.2 0.0 0.1 0.1 4.3 3.8 0.1 0.1 0.1 0.3 0.1 0.0 106.7 0.2 1.0 3.1 0.4 0.5 0.7 0.5 0.5 3.3 1.3 0.0 1.7 2.6 0.3 0.2 0.7 0.0 0.6 4.2 1.8 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 15.8 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 73.1 0.0 0.0 0.0 1.2 500.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.7 0.0 0.0 0.3 3.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 19.1 0.0 1.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.9 0.2 4.9 0.1 0.0 0.0 0.0 0.0 7.2 0.0 0.0 1.6 4.5 0.0 0.0 0.2 0.6 0.0 11.0 0.0 0.4 0.2 0.3 0.4 0.3 0.2 0.0 0.1 0.1 0.2 0.0 0.2 0.5 0.0 0.0 1.1 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 76.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.0 5.2 0.7 0.0 0.0 55.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 188.7 0.5 0.0 0.0 0.0 SIGLEC8 "MGC59785, SAF2, SIGLEC-8, SIGLEC8L" ENSG00000105366 "Sialic acid binding Ig like lectin 8" Q9NYZ4 19 51450847-51458456 "CD markers, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 14.9;lymphoid tissue: 6.8" "Cell type enhanced" "Detected in some" "granulocytes: 44.9;Kupffer cells: 17.7;Microglial cells: 11.2" "Group enriched" "Detected in many" 4 "glioma: 7.2;renal cancer: 2.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 38 "eosinophil: 290.2" "Lineage enriched" "Detected in single" 719 "granulocytes: 290.2" "Cell line enriched" "Detected in some" 44 "HMC-1: 147.5" HPA012556 Uncertain Uncertain Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" Cytosol "HPA012556: AB_1856869" "unprognostic (1.27e-1)" "unprognostic (1.88e-4)" "unprognostic (1.28e-1)" "unprognostic (6.70e-2)" "unprognostic (2.97e-1)" "unprognostic (1.30e-2)" "unprognostic (7.84e-2)" "unprognostic (2.51e-2)" "unprognostic (2.72e-2)" "unprognostic (2.17e-1)" "unprognostic (1.10e-1)" "unprognostic (4.19e-1)" "unprognostic (8.62e-3)" "unprognostic (7.18e-2)" "unprognostic (6.02e-2)" "unprognostic (4.28e-3)" "unprognostic (3.29e-1)" 0.3 4.0 4.9 1.6 5.2 0.5 1.4 5.3 6.1 0.9 1.7 1.8 1.8 0.6 0.7 0.7 0.7 1.4 0.2 4.5 6.2 0.1 0.8 2.5 6.8 13.3 6.6 0.2 0.5 1.0 0.4 0.1 10.1 0.6 1.6 0.7 0.6 0.5 0.1 0.5 2.8 0.9 7.3 6.3 1.4 0.3 11.6 2.1 0.4 0.2 2.5 1.0 0.3 14.9 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 2.3 0.1 0.1 0.0 0.0 147.5 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.5 0.3 0.0 0.0 0.2 3.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.2 1.1 0.1 7.6 0.4 290.2 0.2 0.3 0.1 0.2 0.2 0.1 0.1 0.3 0.1 0.2 2.5 0.3 0.4 0.2 0.1 0.2 4.9 5.2 5.3 6.1 4.5 6.2 13.3 6.6 10.1 7.3 11.6 14.9 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 44.9 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 17.7 0.0 0.0 0.0 2.5 0.0 11.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 SIGLEC9 CD329 ENSG00000129450 "Sialic acid binding Ig like lectin 9" Q9Y336 19 51124906-51136651 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 20.7" "Cell type enhanced" "Detected in some" "Hofbauer cells: 42.1;Kupffer cells: 39.8;Langerhans cells: 13.4;Macrophages: 26.8;monocytes: 10.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "classical monocyte: 198.9;intermediate monocyte: 182.5;myeloid DC: 169.1;neutrophil: 212.0;non-classical monocyte: 121.9" "Group enriched" "Detected in many" 13 "dendritic cells: 169.1;granulocytes: 212.0;monocytes: 198.9" "Group enriched" "Detected in some" 10 "Karpas-707: 23.4;RPMI-8226: 16.5" HPA010682 Uncertain NA NA 270000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" "HPA010682: AB_1079968" "unprognostic (2.31e-1)" "unprognostic (3.99e-2)" "unprognostic (1.03e-2)" "unprognostic (1.36e-1)" "unprognostic (4.69e-2)" "unprognostic (6.86e-2)" "unprognostic (5.10e-2)" "unprognostic (2.10e-1)" "unprognostic (1.31e-1)" "unprognostic (4.73e-2)" "unprognostic (1.06e-1)" "unprognostic (7.03e-3)" "prognostic unfavorable (6.17e-5)" "unprognostic (6.56e-2)" "unprognostic (7.38e-3)" "unprognostic (2.95e-1)" "unprognostic (1.73e-1)" 8.0 5.4 2.0 17.9 2.1 9.0 1.9 2.2 4.3 1.4 2.8 2.1 1.7 0.9 0.2 0.9 2.5 5.0 2.1 1.9 3.4 1.4 5.5 8.3 5.0 5.4 4.0 3.2 1.2 4.1 0.9 7.9 5.0 1.1 2.4 0.3 1.5 0.9 0.4 0.5 2.2 6.4 4.0 20.7 1.4 1.7 6.2 1.4 0.9 1.3 2.5 5.4 0.8 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 23.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 16.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.3 0.0 0.0 1.5 0.0 0.0 0.0 0.0 2.0 1.5 0.0 17.3 198.9 1.6 15.2 182.5 8.6 0.2 2.5 5.8 169.1 0.1 0.6 2.7 212.0 3.1 121.9 9.2 0.9 84.9 2.0 2.1 2.2 4.3 1.9 3.4 5.4 4.0 5.0 4.0 6.2 5.9 0.1 0.0 0.5 0.0 0.9 0.5 0.0 0.0 0.0 0.0 0.0 0.1 1.7 0.0 1.3 0.0 0.0 0.2 2.7 0.0 0.0 0.0 1.8 0.0 0.1 1.1 0.0 0.0 0.2 0.0 0.4 0.5 0.0 0.0 0.0 0.1 5.3 0.8 42.1 0.0 0.2 0.0 0.0 39.8 13.4 0.4 5.0 26.8 0.0 5.6 10.4 0.0 7.2 0.0 0.1 0.0 0.0 2.2 0.4 0.0 0.0 0.1 0.0 0.0 6.6 0.0 0.1 0.0 0.1 0.0 0.1 0.3 1.3 2.8 0.0 0.0 SIGMAR1 "OPRS1, SR-BP1" ENSG00000147955 "Sigma non-opioid intracellular receptor 1" Q99720 9 34634722-34637844 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Receptor "Amyotrophic lateral sclerosis, Disease variant, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 187.6" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 98.7;Hepatocytes: 97.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013470, HPA018002, HPA024071" Enhanced NA NA "Cluster 35: T-regs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 33: Fibroblasts - ECM organization" "CAB013470: AB_2533521, HPA018002: AB_1854802, HPA024071: AB_1854803" "unprognostic (1.39e-1)" "unprognostic (2.64e-1)" "unprognostic (1.56e-1)" "unprognostic (1.95e-1)" "unprognostic (8.06e-2)" "unprognostic (3.71e-2)" "unprognostic (4.89e-2)" "unprognostic (2.50e-2)" "unprognostic (2.58e-2)" "unprognostic (2.01e-3)" "unprognostic (3.88e-2)" "unprognostic (4.28e-1)" "unprognostic (2.78e-2)" "unprognostic (2.46e-1)" "unprognostic (2.39e-1)" "unprognostic (6.44e-3)" "prognostic unfavorable (3.42e-4)" 42.0 52.4 25.2 19.4 25.3 20.5 38.1 26.2 27.1 53.0 27.4 42.0 46.0 50.7 45.0 54.1 46.9 22.1 34.0 25.8 30.2 25.5 187.6 27.5 16.9 28.3 28.7 46.1 45.7 39.0 22.0 27.6 29.4 35.5 31.2 7.2 35.0 38.5 17.6 53.9 40.0 34.8 26.2 24.2 42.1 20.2 33.3 19.1 29.7 13.5 22.2 46.3 43.5 27.1 184.3 162.6 59.8 175.3 205.7 138.7 66.5 127.1 91.2 115.8 105.9 97.6 76.8 87.8 71.9 151.7 69.8 108.8 94.5 151.3 57.8 144.7 175.6 78.0 225.0 112.7 131.7 145.0 67.6 142.9 163.0 131.2 197.7 59.4 90.2 114.5 30.1 156.2 139.7 1.8 88.2 215.2 68.8 101.5 184.4 101.4 59.6 258.3 111.0 36.5 57.6 65.5 123.3 89.5 70.0 32.0 106.9 98.7 68.5 90.0 69.9 96.4 19.2 43.2 71.6 2.5 97.2 123.9 191.8 24.3 39.5 24.2 43.0 39.3 46.2 26.5 62.5 51.3 48.9 21.1 51.7 43.6 10.7 28.7 42.5 35.1 65.5 43.5 25.2 25.3 26.2 27.1 25.8 30.2 28.3 28.7 29.4 26.2 33.3 27.1 11.0 3.2 13.6 6.8 12.3 18.4 16.8 24.6 14.2 10.1 26.8 18.9 9.2 15.7 12.1 7.3 0.0 44.8 10.7 33.0 0.0 33.0 0.9 7.0 23.7 14.4 10.3 23.5 5.6 33.5 98.7 29.2 18.3 10.1 7.0 19.4 13.9 97.5 38.8 5.0 6.4 28.2 12.2 10.5 7.8 1.8 27.4 10.8 19.6 5.6 9.5 13.8 14.4 5.0 4.4 32.1 31.5 25.6 22.4 25.9 58.4 13.7 6.8 7.7 19.7 12.1 23.9 6.0 10.3 40.0 21.5 36.5 13.6 26.2 47.3 16.1 SLA "hSLAP, SLA1, SLAP, SLAP-1" ENSG00000155926 "Src like adaptor" Q13239 8 133036728-133102912 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "bone marrow: 97.4;lymphoid tissue: 156.6" "Cell type enhanced" "Detected in many" "dendritic cells: 224.2;Hofbauer cells: 67.4;Kupffer cells: 199.4;Macrophages: 154.2;NK-cells: 109.2;Plasma cells: 83.0;T-cells: 160.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HMC-1: 47.9;JURKAT: 201.5;Karpas-707: 129.2;MOLT-4: 35.8;U-266/84: 76.1;U-937: 55.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012296, HPA074192" Enhanced Approved "Nuclear membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Nuclear membrane, Cytosol" "HPA012296: AB_1856946, HPA074192: AB_2686673" "unprognostic (1.19e-2)" "unprognostic (6.29e-3)" "unprognostic (2.73e-3)" "unprognostic (6.07e-3)" "unprognostic (1.66e-2)" "unprognostic (1.10e-2)" "unprognostic (1.39e-1)" "unprognostic (1.02e-1)" "unprognostic (1.67e-1)" "unprognostic (9.25e-2)" "unprognostic (3.03e-2)" "unprognostic (2.73e-1)" "unprognostic (2.80e-3)" "unprognostic (2.66e-1)" "unprognostic (3.05e-2)" "unprognostic (8.60e-2)" "unprognostic (1.65e-1)" 25.2 13.1 9.5 82.9 6.4 97.4 9.5 6.1 11.5 11.1 8.2 10.8 7.9 5.2 2.9 9.4 7.0 20.9 5.2 8.2 9.1 6.4 16.9 25.9 78.6 12.0 8.4 3.0 5.8 3.1 3.1 15.2 10.3 5.2 8.4 1.3 4.6 3.6 1.5 4.0 20.7 12.5 9.7 70.3 12.5 1.4 16.9 156.6 27.6 4.4 71.0 22.0 4.2 14.6 0.3 0.0 0.0 0.0 0.0 0.1 0.6 0.0 1.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.1 0.0 0.0 0.0 2.9 0.1 2.3 0.0 0.0 0.0 6.3 47.9 0.8 0.0 0.6 0.0 0.2 0.0 201.5 0.1 129.2 0.0 0.0 35.8 9.3 0.0 0.0 0.0 0.2 0.3 7.8 0.0 0.0 0.0 1.0 0.0 0.1 0.1 3.1 0.0 15.3 0.0 0.1 0.3 0.2 0.1 6.9 76.1 0.0 0.6 55.6 0.0 0.7 110.2 203.6 87.6 123.1 110.1 41.0 79.7 88.2 79.8 48.3 75.3 77.4 262.3 132.6 148.4 6.3 124.4 158.9 9.5 6.4 6.1 11.5 8.2 9.1 12.0 8.4 10.3 9.7 16.9 14.6 2.4 9.6 19.1 0.7 36.6 2.2 0.3 0.0 0.0 9.7 0.9 1.3 3.3 1.5 10.5 0.0 0.0 0.4 224.2 0.2 0.0 0.2 0.2 0.7 0.7 5.9 0.0 13.2 1.0 0.0 1.2 4.5 3.6 0.5 37.2 1.7 8.9 2.9 67.4 0.0 1.3 0.5 0.0 199.4 15.0 1.0 0.3 154.2 5.4 14.0 36.7 0.1 109.2 0.0 0.1 0.0 0.0 0.0 83.0 0.1 0.0 0.3 5.1 0.3 6.6 1.4 1.9 0.0 0.1 0.3 2.7 0.1 160.0 0.1 0.1 0.2 SLAMF1 "CD150, SLAM" ENSG00000117090 "Signaling lymphocytic activation molecule family member 1" Q13291 1 160608106-160647295 "CD markers, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Cell adhesion, Host-virus interaction, Immunity, Innate immunity, Phagocytosis" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "lymphoid tissue: 76.6" "Cell type enhanced" "Detected in some" "B-cells: 29.8;Melanocytes: 14.2;monocytes: 22.9;Plasma cells: 49.2;T-cells: 35.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 66.3" "Group enriched" "Detected in many" 10 "B-cells: 22.7;T-cells: 66.3" "Cell line enriched" "Detected in some" 104 "HDLM-2: 195.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB002438, HPA069319" Enhanced "Secreted to blood" NA NA 350000 "Cluster 13: T-cells - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "CAB002438: AB_564011, HPA069319: AB_2732129" "unprognostic (2.99e-3)" "unprognostic (3.33e-4)" "unprognostic (2.93e-4)" "unprognostic (1.38e-4)" "unprognostic (5.87e-2)" "unprognostic (6.06e-5)" "unprognostic (1.64e-2)" "unprognostic (1.70e-3)" "unprognostic (1.69e-2)" "unprognostic (2.74e-4)" "unprognostic (6.12e-2)" "unprognostic (3.58e-1)" "unprognostic (1.24e-7)" "unprognostic (2.46e-1)" "unprognostic (8.46e-2)" "unprognostic (1.22e-1)" "unprognostic (2.18e-2)" 1.1 0.5 0.0 13.6 0.0 6.6 1.6 0.0 0.1 1.1 0.3 2.6 3.7 0.4 0.1 1.4 0.4 2.3 1.1 0.0 0.0 0.9 0.9 2.1 21.6 0.3 0.0 0.4 0.3 0.1 0.1 3.0 0.1 0.6 3.0 0.0 1.7 0.3 0.3 0.7 3.9 0.9 0.1 6.7 3.9 0.2 0.1 76.6 0.6 0.0 19.1 8.2 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 195.4 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.2 1.4 0.4 0.0 1.8 0.0 0.1 0.2 0.0 10.7 0.0 66.3 16.5 46.3 33.0 0.3 22.7 17.5 4.4 0.6 0.0 0.1 4.4 61.7 9.5 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.1 0.1 0.1 1.4 0.0 5.2 0.0 29.8 2.0 0.1 0.0 0.0 0.0 0.7 0.3 0.3 0.0 0.6 1.8 0.0 0.0 4.8 0.0 0.0 0.0 4.1 0.1 0.1 2.0 0.0 0.0 0.0 0.0 0.0 1.2 0.5 0.0 1.3 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.8 10.7 8.5 0.0 5.2 14.2 1.0 22.9 0.0 0.0 0.5 0.1 0.0 0.0 0.0 49.2 0.2 0.0 0.1 0.0 0.0 0.0 0.2 0.8 0.1 0.1 0.0 1.7 0.1 35.6 0.0 0.1 0.1 SLC10A3 "DXS253E, P3" ENSG00000126903 "Solute carrier family 10 member 3" P09131 X 154487306-154490690 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 63.6;Syncytiotrophoblasts: 103.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 10 "basophil: 218.6" "Lineage enriched" "Detected in all" 17 "granulocytes: 218.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021656 Approved Approved "Intermediate filaments" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 51: Myeloid cells - Hemostasis" "Intermediate filaments" "HPA021656: AB_1856955" "unprognostic (1.60e-1)" "prognostic favorable (4.53e-4)" "prognostic unfavorable (4.15e-5)" "unprognostic (8.00e-3)" "prognostic unfavorable (9.97e-4)" "unprognostic (5.47e-2)" "unprognostic (2.28e-3)" "unprognostic (9.76e-2)" "unprognostic (1.63e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (7.22e-4)" "unprognostic (3.42e-1)" "unprognostic (2.52e-3)" "unprognostic (6.23e-2)" "unprognostic (2.99e-1)" "unprognostic (7.29e-2)" "unprognostic (2.99e-2)" 23.3 22.9 6.1 13.1 6.2 34.0 21.0 6.8 7.9 27.1 5.8 22.5 13.9 29.6 18.4 31.2 22.8 21.3 23.2 5.9 6.1 20.6 10.3 22.7 15.1 7.4 6.8 40.8 22.8 9.6 18.8 21.1 7.4 22.9 8.3 2.0 17.4 15.7 18.3 42.9 18.7 13.5 6.9 19.3 18.9 8.9 8.1 9.8 20.6 9.4 11.2 31.8 26.0 7.7 66.4 27.0 7.3 38.3 25.2 27.6 48.9 49.2 29.2 32.5 32.3 25.0 31.8 51.0 91.1 46.8 41.3 55.9 24.4 24.7 8.6 32.7 11.8 15.9 36.0 20.3 47.0 19.0 24.9 34.8 28.1 29.9 15.8 28.5 22.6 8.7 17.6 48.6 21.6 90.0 10.2 17.0 5.9 32.4 54.9 16.8 19.9 38.8 24.7 24.2 6.8 12.0 29.8 55.4 13.0 8.5 17.9 15.0 29.5 38.0 23.9 89.6 63.2 34.3 35.6 52.8 40.9 39.6 20.2 218.6 4.5 21.1 12.9 6.5 9.6 5.3 8.5 9.2 3.9 5.2 6.0 5.9 6.1 8.8 5.6 9.5 6.4 6.3 6.1 6.2 6.8 7.9 5.9 6.1 7.4 6.8 7.4 6.9 8.1 7.7 13.3 3.2 7.0 2.3 21.1 22.6 27.1 15.2 50.7 2.8 13.7 11.8 4.0 15.7 7.3 18.4 6.2 49.5 17.4 22.1 7.9 17.8 3.6 13.0 14.8 15.8 10.2 11.1 1.6 19.4 63.6 21.2 13.7 21.0 12.7 15.8 16.8 2.3 19.4 3.3 1.4 15.5 4.1 8.4 19.6 1.2 27.1 22.7 3.6 1.0 13.2 3.0 23.7 1.5 1.6 20.9 16.0 13.2 19.8 14.1 17.2 10.4 6.9 1.9 6.6 12.1 14.3 1.9 2.9 45.5 27.8 103.0 24.5 5.4 11.7 23.5 SLC2A1 "CSE, DYT18, DYT9, GLUT, GLUT1, HTLVR" ENSG00000117394 "Solute carrier family 2 member 1" P11166 1 42925353-42958893 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Cancer-related genes, Cataract, Disease variant, Dystonia, Epilepsy, Hereditary hemolytic anemia, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 98.7;skin 1: 79.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 833.8;Erythroid cells: 520.4;Extravillous trophoblasts: 536.4;Syncytiotrophoblasts: 2482.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "BEWO: 241.0;CACO-2: 219.9;Hep G2: 157.4" "Low region specificity" "Detected in all" "CAB002759, HPA031345, HPA058494" Enhanced Supported Enhanced "Plasma membrane" No No 2000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane" "CAB002759: , HPA031345: AB_2673835, HPA058494: AB_2683734" "unprognostic (3.60e-2)" "unprognostic (5.85e-3)" "unprognostic (7.59e-2)" "unprognostic (1.31e-2)" "unprognostic (4.10e-3)" "unprognostic (3.22e-2)" "prognostic unfavorable (3.65e-8)" "prognostic unfavorable (1.09e-4)" "unprognostic (1.10e-1)" "unprognostic (4.84e-2)" "prognostic unfavorable (4.39e-5)" "unprognostic (1.87e-1)" "prognostic unfavorable (4.55e-9)" "unprognostic (1.11e-1)" "unprognostic (9.49e-2)" "unprognostic (1.17e-1)" "prognostic unfavorable (4.05e-4)" 6.9 3.6 24.1 2.5 26.1 41.6 7.8 33.7 27.7 28.6 43.6 6.1 0.4 5.1 1.4 54.1 8.2 1.7 10.0 20.6 28.5 14.2 1.7 3.3 1.0 31.9 29.3 5.5 2.1 4.5 4.8 98.7 34.5 6.0 1.0 24.6 17.6 5.1 2.0 79.8 4.6 0.4 24.7 7.5 8.4 2.1 41.2 1.0 3.0 1.5 2.1 19.3 54.2 29.4 60.5 52.9 66.3 6.2 3.5 1.2 241.0 47.8 36.9 15.5 27.8 219.9 96.3 22.2 138.9 6.0 26.5 43.6 12.5 52.3 14.8 16.4 10.3 29.8 20.9 157.4 12.9 16.8 8.1 3.3 21.3 18.3 20.5 96.7 2.9 12.8 81.2 1.5 11.7 46.6 7.4 11.7 35.1 22.1 17.9 8.4 20.6 23.3 21.7 17.9 27.0 23.8 47.7 95.6 11.0 70.0 3.8 16.9 14.9 25.6 28.6 6.1 83.8 5.3 6.5 11.5 57.1 8.2 25.5 0.5 0.1 1.2 10.6 0.3 8.5 10.9 5.1 6.7 3.7 8.3 3.8 4.8 0.2 4.3 0.1 18.4 6.2 4.0 24.1 26.1 33.7 27.7 20.6 28.5 31.9 29.3 34.5 24.7 41.2 29.4 3.1 0.0 1.8 12.7 25.4 286.1 48.8 286.3 66.0 15.8 41.4 21.8 26.7 20.0 159.3 27.6 66.7 833.8 33.5 53.1 5.9 53.2 4.0 112.1 46.0 100.5 18.4 520.4 2.8 11.7 536.4 25.9 11.7 118.9 6.3 6.8 2.2 2.1 84.8 5.0 3.2 22.4 65.1 1.6 34.2 0.3 7.8 5.0 21.4 71.2 36.0 350.1 18.6 8.0 9.9 120.3 51.9 14.7 11.6 31.2 1.9 2.2 118.1 32.1 0.0 9.8 32.1 0.1 2.4 99.1 238.3 2482.5 20.8 5.5 11.8 105.8 SLC35F6 "ANT2BP, C2orf18, FLJ20555, TANGO9" ENSG00000213699 "Solute carrier family 35 member F6" Q8N357 2 26764284-26781231 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HHSteC: 129.9;Karpas-707: 117.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034655 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "Nucleoplasm, Cytosol" "HPA034655: AB_10696359" "unprognostic (2.26e-1)" "unprognostic (7.45e-2)" "unprognostic (1.74e-1)" "unprognostic (1.54e-1)" "unprognostic (7.71e-2)" "unprognostic (1.03e-1)" "prognostic unfavorable (1.11e-4)" "prognostic unfavorable (3.71e-4)" "unprognostic (3.44e-2)" "unprognostic (1.35e-1)" "unprognostic (3.24e-1)" "unprognostic (2.60e-1)" "unprognostic (3.84e-1)" "unprognostic (1.07e-2)" "unprognostic (9.95e-2)" "unprognostic (1.10e-1)" "unprognostic (1.06e-2)" 18.6 20.7 9.6 7.3 10.5 4.6 16.2 10.1 9.2 14.5 8.4 10.1 7.9 11.9 7.3 22.0 10.7 7.3 13.8 9.6 11.8 19.5 17.7 11.9 6.5 13.9 12.9 8.5 10.3 21.3 10.8 9.4 12.3 11.4 5.7 5.8 14.5 8.1 12.8 21.2 10.0 10.1 10.4 10.8 11.3 5.1 13.0 5.7 16.0 9.9 7.6 12.1 13.0 11.6 24.6 43.6 12.3 32.6 41.7 19.4 20.4 14.9 20.3 16.8 15.2 27.9 44.5 6.6 23.4 18.7 42.0 29.4 18.1 26.9 11.8 11.5 10.1 7.6 16.4 23.3 129.9 7.8 36.4 29.8 26.9 18.9 62.7 7.6 19.9 9.6 14.2 117.3 16.9 40.5 10.0 7.0 7.6 17.2 10.9 8.9 35.9 10.9 44.1 20.3 9.6 12.7 22.8 37.4 25.4 10.1 14.1 8.2 19.2 21.8 24.0 30.7 15.2 23.9 32.6 12.9 23.6 13.4 21.0 12.1 18.1 8.0 11.9 25.6 7.0 4.8 8.2 10.8 11.4 3.6 5.3 7.9 11.7 13.6 30.9 7.8 5.9 9.5 9.6 10.5 10.1 9.2 9.6 11.8 13.9 12.9 12.3 10.4 13.0 11.6 39.0 12.8 10.5 11.8 5.9 17.0 13.2 10.2 7.4 17.2 17.5 10.2 13.5 28.6 11.1 33.1 6.2 24.1 12.0 21.5 7.9 34.2 1.7 13.4 29.7 20.8 9.1 0.8 6.9 38.7 22.3 25.2 12.2 22.8 1.3 11.9 31.8 25.4 51.2 15.2 7.9 11.2 8.2 61.0 16.8 1.5 18.3 28.8 28.4 4.7 19.8 19.2 11.3 9.0 10.8 48.2 14.3 12.0 5.5 18.3 21.5 57.2 9.0 11.1 26.3 17.8 20.2 3.7 7.1 14.9 25.7 38.0 10.6 16.8 11.2 11.7 SLC35G2 "DKFZp564K2464, MGC3295, TMEM22" ENSG00000168917 "Solute carrier family 35 member G2" Q8TBE7 3 136818647-136855888 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 54.2;Early spermatids: 65.4;Inhibitory neurons: 42.4;Spermatocytes: 35.5" "Cancer enhanced" "Detected in many" "glioma: 6.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory CD8 T-cell: 1.0" "Lineage enriched" "Detected in single" 10 "T-cells: 1.0" "Cell line enhanced" "Detected in many" "BJ hTERT+: 73.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052054, HPA064728" Approved Supported "Plasma membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA052054: AB_2681709, HPA064728: AB_2685336" "unprognostic (1.04e-1)" "unprognostic (1.46e-2)" "unprognostic (6.91e-4)" "unprognostic (2.56e-4)" "unprognostic (5.34e-2)" "unprognostic (6.73e-2)" "unprognostic (1.16e-5)" "unprognostic (1.83e-3)" "unprognostic (1.12e-1)" "unprognostic (6.39e-2)" "unprognostic (1.49e-2)" "unprognostic (3.32e-1)" "prognostic unfavorable (1.16e-7)" "unprognostic (1.00e-2)" "unprognostic (1.69e-1)" "unprognostic (1.07e-2)" "unprognostic (2.30e-2)" 14.9 15.4 20.9 2.1 21.2 0.5 11.1 23.1 26.4 5.1 16.5 3.8 1.0 4.3 4.6 2.6 5.7 5.3 8.1 20.0 24.4 3.9 4.4 7.0 1.9 21.4 25.0 5.5 7.6 6.7 19.3 7.4 26.9 4.1 2.0 5.3 3.1 2.6 2.4 3.7 2.9 5.1 22.1 3.2 2.9 14.4 22.6 2.8 8.5 5.4 1.2 6.5 5.0 21.0 3.9 10.7 10.6 4.8 20.8 17.1 0.0 16.9 73.1 24.7 37.0 10.1 5.7 0.0 12.7 17.5 39.3 1.3 12.7 0.7 22.8 0.1 3.5 3.2 12.0 6.3 26.6 0.1 0.0 24.2 1.8 21.5 5.9 18.0 18.8 6.8 1.8 0.1 32.1 0.0 4.7 3.3 2.3 0.0 7.9 4.2 7.1 0.2 21.1 0.9 17.5 11.7 13.7 0.0 24.0 3.6 0.0 1.8 13.1 18.4 4.7 8.2 18.6 0.0 0.0 0.0 25.4 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 20.9 21.2 23.1 26.4 20.0 24.4 21.4 25.0 26.9 22.1 22.6 21.0 22.4 12.8 7.0 54.2 2.5 3.3 4.9 12.0 7.4 4.7 0.7 0.8 2.5 1.5 7.1 1.8 12.5 1.3 2.7 0.8 1.9 3.3 65.4 1.0 1.6 30.6 4.2 4.4 34.0 10.7 1.3 12.4 0.5 1.3 2.5 3.6 27.8 2.3 0.7 6.7 42.4 1.0 0.0 2.2 7.3 30.3 9.9 2.1 3.6 17.8 3.7 7.8 15.5 15.6 6.1 10.0 0.1 3.0 3.7 4.7 0.6 0.7 1.4 4.6 6.6 4.7 4.8 35.5 16.1 1.2 3.0 2.2 3.8 3.1 0.6 2.0 SLC47A1 "FLJ10847, MATE1" ENSG00000142494 "Solute carrier family 47 member 1" Q96FL8 17 19495385-19579034 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 127.3;kidney: 100.3;liver: 103.9" "Cell type enhanced" "Detected in many" "Granulosa cells: 189.2;Hepatocytes: 43.3;Proximal tubular cells: 52.9;Skeletal myocytes: 67.8" "Cancer enhanced" "Detected in many" "renal cancer: 37.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "eosinophil: 12.2;plasmacytoid DC: 6.6" "Group enriched" "Detected in many" 6 "dendritic cells: 6.6;granulocytes: 12.2" "Cell line enhanced" "Detected in many" "A549: 21.3;AN3-CA: 16.7;Hep G2: 41.5;U-266/70: 31.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA021987 Enhanced NA NA 18000 "Cluster 49: Eosinophils - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 40: Granulosa cells - Unknown function" "HPA021987: AB_1857185" "unprognostic (1.17e-2)" "unprognostic (1.94e-2)" "unprognostic (1.46e-1)" "prognostic favorable (5.54e-8)" "unprognostic (7.87e-2)" "unprognostic (8.34e-2)" "unprognostic (2.92e-2)" "prognostic favorable (1.88e-5)" "unprognostic (4.84e-2)" "unprognostic (6.89e-2)" "unprognostic (6.75e-2)" "unprognostic (1.60e-1)" "prognostic favorable (1.06e-5)" "unprognostic (1.77e-1)" "unprognostic (1.48e-1)" "unprognostic (2.91e-2)" "unprognostic (9.40e-2)" 1.9 127.3 2.1 0.8 2.6 2.7 1.3 3.5 15.8 29.4 9.3 2.0 1.3 16.2 2.5 1.9 7.4 3.8 5.4 15.7 1.6 100.3 103.9 7.0 1.6 3.0 2.5 7.7 0.3 1.4 16.5 0.4 3.1 6.3 1.0 1.2 2.6 12.3 34.1 25.0 1.3 7.7 2.5 3.7 1.2 14.5 4.3 1.5 6.2 37.7 1.3 1.0 10.6 3.3 0.1 21.3 0.6 16.7 0.5 0.1 0.1 0.6 0.5 2.5 2.3 0.0 0.6 0.2 3.9 3.1 8.3 0.1 7.4 0.6 0.6 0.1 9.8 0.2 10.6 41.5 0.2 0.2 0.5 0.4 3.7 1.9 0.3 2.8 5.9 0.0 0.0 0.0 0.0 3.0 0.1 0.4 2.2 0.3 0.8 0.2 0.2 0.2 0.0 1.3 3.9 3.4 7.0 0.1 1.9 5.6 7.1 1.9 0.0 0.1 0.8 0.3 2.0 31.0 13.1 0.1 0.8 0.1 3.6 0.3 1.4 12.2 0.3 0.9 0.1 0.1 0.1 0.1 0.2 0.1 0.2 0.6 0.2 0.0 0.1 6.6 0.0 0.5 2.1 2.6 3.5 15.8 15.7 1.6 3.0 2.5 3.1 2.5 4.3 3.3 0.5 6.4 3.7 0.7 1.3 4.7 2.3 0.4 6.2 0.9 0.1 0.8 4.1 4.3 0.1 1.8 0.0 0.0 1.7 0.0 3.9 0.1 15.5 3.0 1.3 1.2 0.0 0.0 3.5 0.0 0.0 4.4 0.0 9.2 5.7 189.2 0.0 43.3 1.5 0.0 14.4 0.0 0.0 2.9 1.2 4.8 3.7 2.5 1.8 3.7 0.4 1.4 0.0 2.5 0.3 0.0 0.0 1.5 3.9 2.3 0.0 52.9 0.8 0.9 6.6 67.8 3.3 0.6 1.1 1.1 6.7 0.0 1.7 0.3 0.0 1.5 SLC49A3 "FLJ22269, LP2561, MFSD7" ENSG00000169026 "Solute carrier family 49 member 3" Q6UXD7 4 681829-689271 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 12.8;Breast glandular cells: 14.6;Collecting duct cells: 14.7;Ductal cells: 19.2;Extravillous trophoblasts: 33.9;Hofbauer cells: 35.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "BEWO: 8.7;CAPAN-2: 5.8;SK-BR-3: 8.2;T-47d: 25.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA043593 Uncertain NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 77: Retina - Visual perception" "Cluster 6: T47d - Mammary gland" "Cluster 4: Macrophages - Innate immune response" "HPA043593: AB_10959611" "unprognostic (1.10e-2)" "unprognostic (1.91e-1)" "unprognostic (8.77e-2)" "unprognostic (4.70e-2)" "unprognostic (9.40e-2)" "unprognostic (1.84e-3)" "unprognostic (2.22e-1)" "unprognostic (1.56e-2)" "unprognostic (1.83e-1)" "unprognostic (2.56e-1)" "unprognostic (9.22e-2)" "unprognostic (2.08e-1)" "prognostic favorable (2.66e-5)" "unprognostic (8.35e-2)" "unprognostic (4.92e-2)" "unprognostic (7.48e-2)" "unprognostic (1.11e-1)" 8.2 3.2 2.4 4.4 2.1 3.5 9.0 2.7 3.0 4.5 3.5 4.2 5.9 3.4 4.2 4.4 3.3 3.7 8.3 1.7 2.3 8.3 5.8 8.1 3.0 3.2 2.2 1.2 4.8 4.6 1.9 2.7 3.0 5.0 2.3 12.6 8.4 2.1 3.0 10.2 5.9 2.1 2.7 8.5 8.4 8.9 3.5 0.6 8.5 1.9 1.7 4.3 4.9 2.9 0.1 0.1 2.7 1.9 1.9 3.7 8.7 1.0 0.0 0.7 0.6 0.4 5.8 0.1 0.2 4.5 0.4 0.2 0.0 0.0 0.2 0.6 0.6 1.6 0.7 0.2 0.8 0.0 1.2 2.5 0.0 3.4 0.0 0.0 1.3 0.3 0.4 0.5 0.0 0.1 0.1 0.7 0.3 0.4 0.5 0.0 0.3 0.6 0.0 0.3 0.9 0.7 0.0 8.2 0.5 0.5 25.8 1.6 0.3 0.8 0.3 0.4 0.3 2.8 1.6 0.1 0.3 0.7 0.0 0.0 0.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.3 0.4 0.2 0.0 0.1 0.3 2.4 2.1 2.7 3.0 1.7 2.3 3.2 2.2 3.0 2.7 3.5 2.9 12.8 3.2 1.7 0.0 0.4 0.0 0.0 0.0 0.0 0.0 14.6 8.4 0.0 0.0 1.8 14.7 0.0 0.7 3.1 0.0 1.9 19.2 0.0 2.1 6.0 4.3 0.0 0.0 0.0 0.4 33.9 4.3 0.0 4.1 0.0 0.8 0.0 0.0 35.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 0.0 0.0 3.1 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.8 0.0 0.0 2.4 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 4.9 0.7 0.5 0.0 0.0 SLC4A11 "BTR1, CDPD1, CHED2, dJ794I6.2, FECD4, NaBC1" ENSG00000088836 "Solute carrier family 4 member 11" Q8NBS3 20 3227417-3239559 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Anion exchange, Ion transport, Symport, Transport" "Corneal dystrophy, Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 51.3;salivary gland: 54.0;thyroid gland: 60.9" "Cell type enhanced" "Detected in many" "Club cells: 25.5;Collecting duct cells: 112.2;Ionocytes: 79.3;Respiratory ciliated cells: 48.1;Sertoli cells: 26.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 70.6;Hep G2: 43.0;RT4: 30.7" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA018120, HPA058377" Uncertain Uncertain Nucleoplasm,Vesicles NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm Vesicles "HPA018120: AB_1857186, HPA058377: " "unprognostic (2.33e-1)" "prognostic favorable (9.03e-4)" "unprognostic (1.18e-2)" "unprognostic (3.05e-2)" "unprognostic (1.00e-1)" "unprognostic (6.52e-2)" "unprognostic (9.66e-3)" "unprognostic (3.73e-2)" "unprognostic (3.10e-3)" "unprognostic (1.52e-3)" "unprognostic (2.94e-1)" "unprognostic (2.64e-1)" "prognostic favorable (6.21e-6)" "unprognostic (7.37e-2)" "unprognostic (4.30e-1)" "unprognostic (2.33e-1)" "unprognostic (6.89e-3)" 2.4 6.9 4.5 0.7 3.5 0.4 3.4 2.3 3.1 10.9 5.6 0.4 0.1 0.5 2.6 16.5 1.7 1.1 0.8 2.9 1.4 51.3 0.2 2.0 1.4 2.0 2.3 0.2 0.5 0.6 4.3 0.2 2.6 5.4 0.3 0.4 54.0 7.0 5.2 12.8 0.6 0.3 0.8 0.7 2.5 5.9 4.3 1.0 60.9 0.1 1.8 3.4 5.8 1.9 11.0 15.5 1.8 7.9 5.1 1.3 21.1 5.4 3.4 2.8 1.6 1.1 14.1 0.0 6.1 1.9 6.6 70.6 8.3 16.8 0.5 0.1 3.2 0.7 7.5 43.0 3.2 4.0 13.6 0.7 6.8 3.4 3.2 2.3 7.0 9.8 1.6 9.7 2.9 7.2 0.5 0.4 12.1 13.6 20.7 2.6 10.3 3.5 16.9 30.7 0.9 4.9 2.7 17.5 0.3 5.4 6.7 7.0 12.1 2.1 7.0 0.5 2.7 0.4 0.6 0.1 0.1 2.8 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 4.5 3.5 2.3 3.1 2.9 1.4 2.0 2.3 2.6 0.8 4.3 1.9 0.8 0.0 0.0 1.6 0.0 0.8 2.2 16.3 8.0 0.2 4.9 4.4 1.1 0.0 25.5 112.2 0.0 0.1 0.6 0.8 0.0 0.7 5.8 2.3 0.6 0.7 0.0 0.0 0.3 0.5 0.1 0.3 5.1 4.2 0.0 0.2 1.1 0.0 0.4 0.0 0.1 0.2 79.3 0.3 0.0 2.2 0.0 0.5 0.0 0.0 0.6 0.1 0.0 0.0 0.3 3.0 1.3 0.4 0.0 3.7 0.0 0.5 48.1 0.2 26.3 0.6 5.8 3.0 4.7 3.3 0.4 0.0 0.2 0.1 0.2 5.7 SLC4A3 "AE3, SLC2C" ENSG00000114923 "Solute carrier family 4 member 3" P48751 2 219627394-219641980 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Anion exchange, Antiport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "heart muscle: 283.1;ovary: 124.1" "Group enriched" "Detected in many" 9 "Cardiomyocytes: 207.1;Horizontal cells: 558.6" "Cancer enhanced" "Detected in all" "glioma: 13.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 34 "myeloid DC: 1.4;plasmacytoid DC: 5.8" "Lineage enriched" "Detected in single" 54 "dendritic cells: 5.8" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 13.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063498 Approved Nucleoplasm NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "HPA063498: AB_2685025" "unprognostic (9.49e-2)" "unprognostic (5.72e-3)" "unprognostic (8.92e-4)" "unprognostic (1.77e-2)" "unprognostic (6.61e-3)" "unprognostic (1.47e-1)" "unprognostic (2.60e-1)" "unprognostic (2.39e-2)" "unprognostic (4.13e-2)" "unprognostic (2.32e-2)" "unprognostic (1.01e-2)" "unprognostic (1.88e-1)" "unprognostic (8.15e-3)" "unprognostic (1.97e-1)" "unprognostic (3.27e-2)" "unprognostic (1.06e-1)" "prognostic unfavorable (4.12e-4)" 6.3 16.7 36.1 1.0 36.6 0.4 3.9 21.2 32.1 11.4 6.3 2.9 0.7 15.3 2.7 3.2 9.3 2.3 283.1 31.7 34.5 9.3 0.3 1.6 0.9 44.1 20.7 124.1 3.9 7.7 41.4 2.7 43.1 10.4 0.2 13.0 3.8 5.3 0.9 2.0 1.1 3.7 10.6 3.3 2.7 14.2 32.7 1.0 2.5 0.6 0.6 2.6 4.7 18.0 6.9 0.2 2.3 6.8 0.4 0.4 4.9 4.1 4.2 5.4 3.8 4.8 3.8 0.0 1.6 1.5 9.3 3.8 1.2 7.3 1.6 0.0 1.0 0.0 0.1 0.1 1.1 0.1 0.3 3.1 7.0 0.0 2.1 13.4 0.0 0.0 0.3 0.0 1.6 2.3 0.0 0.0 3.8 0.2 5.5 0.0 0.0 0.0 3.7 1.5 1.3 6.7 2.7 6.9 3.7 7.2 0.7 1.7 0.0 3.4 6.0 0.0 3.3 0.0 0.0 0.0 2.7 0.0 9.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 36.1 36.6 21.2 32.1 31.7 34.5 44.1 20.7 43.1 10.6 32.7 18.0 0.3 0.0 0.0 19.2 0.2 0.3 0.7 1.5 0.0 14.4 2.2 4.8 207.1 0.0 0.8 1.8 0.0 11.4 13.5 0.0 1.9 3.0 2.3 0.9 3.5 1.8 0.0 0.0 11.5 1.7 3.0 10.4 0.0 1.4 0.0 38.3 0.0 0.0 1.8 558.6 32.7 0.0 0.0 0.3 5.6 25.6 15.2 1.1 0.0 3.7 1.3 7.6 0.0 3.5 0.6 1.1 0.0 22.6 0.0 0.4 0.0 0.3 0.2 7.5 6.6 3.9 3.5 0.6 1.2 0.0 0.9 13.8 0.1 8.7 0.0 0.1 SLC5A9 SGLT4 ENSG00000117834 "Solute carrier family 5 member 9" Q2M3M2 1 48222685-48248644 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "intestine: 43.3" "Group enriched" "Detected in some" 4 "Alveolar cells type 1: 22.4;Proximal enterocytes: 84.0" "Cancer enhanced" "Detected in many" "liver cancer: 4.1;renal cancer: 3.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "Hep G2: 15.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA050263 Approved "Actin filaments,Cytosol" NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 45: Enterocytes - Digestion" "Actin filaments" Cytosol "HPA050263: " "unprognostic (3.09e-3)" "unprognostic (1.89e-1)" "unprognostic (6.75e-2)" "unprognostic (5.66e-2)" "unprognostic (2.36e-1)" "unprognostic (1.35e-3)" "unprognostic (3.64e-2)" "unprognostic (4.59e-2)" "unprognostic (3.60e-2)" "unprognostic (1.59e-1)" "unprognostic (7.42e-2)" "unprognostic (1.97e-1)" "prognostic unfavorable (1.84e-5)" "unprognostic (4.56e-1)" "unprognostic (2.11e-1)" "unprognostic (4.30e-3)" "unprognostic (1.06e-2)" 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.2 0.8 43.3 0.1 1.2 0.2 0.1 2.5 0.0 0.0 0.0 3.8 7.8 3.0 0.0 0.2 0.2 0.0 3.9 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.8 0.1 1.1 42.0 0.0 0.0 0.0 0.5 0.5 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 15.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.2 0.2 0.1 0.0 0.2 0.3 0.2 22.4 1.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.5 2.8 0.0 0.0 0.0 0.0 0.0 3.1 1.9 0.5 6.3 0.5 0.1 0.1 0.0 0.0 0.3 0.2 0.0 0.3 0.0 0.5 4.5 0.0 0.7 4.4 0.1 0.0 0.2 2.9 0.0 1.3 0.0 11.0 0.3 0.3 0.0 1.9 0.1 0.0 0.0 7.5 2.9 0.1 1.7 0.4 0.0 0.0 84.0 4.1 0.0 0.0 0.0 0.2 0.1 0.6 0.3 0.0 0.0 0.0 0.1 0.0 3.0 0.0 SLC6A11 GAT3 ENSG00000132164 "Solute carrier family 6 member 11" P48066 3 10816201-10940714 "Metabolic proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "brain: 153.3" "Cell type enhanced" "Detected in some" "Astrocytes: 85.2;Excitatory neurons: 13.7;Inhibitory neurons: 25.8;Muller glia cells: 26.4;Oligodendrocyte precursor cells: 23.1" "Cancer enhanced" "Detected in many" "glioma: 7.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 5.2;HaCaT: 13.5;Hep G2: 16.0;hTCEpi: 11.9;NTERA-2: 6.7;T-47d: 5.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037981 Supported Supported Uncertain Nucleoplasm,Vesicles NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm Vesicles "HPA037981: AB_10671383" "unprognostic (6.04e-2)" "unprognostic (8.01e-2)" "unprognostic (1.21e-7)" "unprognostic (8.60e-2)" "unprognostic (8.68e-2)" "unprognostic (9.72e-3)" "unprognostic (6.39e-3)" "unprognostic (9.77e-2)" "unprognostic (2.35e-1)" "unprognostic (3.92e-2)" "unprognostic (8.78e-2)" "unprognostic (1.51e-3)" "unprognostic (6.06e-2)" "unprognostic (4.44e-2)" "unprognostic (9.83e-2)" "unprognostic (2.31e-2)" 0.0 0.0 50.5 0.0 78.7 0.0 1.1 57.3 32.6 0.7 9.6 0.0 0.0 0.5 0.1 8.2 0.5 0.0 0.0 22.6 96.6 0.0 0.1 0.0 0.0 60.0 128.4 0.0 0.1 0.5 0.3 0.4 61.9 0.7 0.0 11.0 1.0 0.0 0.2 5.7 0.0 0.1 41.8 0.4 0.0 1.4 153.3 0.0 0.0 0.0 0.1 0.4 1.8 21.1 5.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 13.5 0.0 2.2 0.0 0.0 0.2 0.3 0.0 16.0 0.0 0.0 0.0 0.0 11.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 3.1 1.9 4.5 3.9 0.1 0.0 0.1 5.0 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 50.5 78.7 57.3 32.6 22.6 96.6 60.0 128.4 61.9 41.8 153.3 21.1 0.0 0.0 0.0 85.2 0.0 1.3 0.7 0.3 4.0 8.4 0.9 0.9 1.4 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.0 13.7 0.0 7.2 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 25.8 0.0 0.0 0.0 0.8 0.9 3.4 0.2 0.0 6.5 0.0 26.4 0.0 23.1 0.8 0.2 0.0 6.8 0.0 0.5 0.0 0.0 0.0 1.5 0.0 0.6 0.1 0.6 1.8 10.6 3.7 1.0 0.1 0.0 0.0 1.7 SLC6A17 ENSG00000197106 "Solute carrier family 6 member 17" Q9H1V8 1 110150494-110202202 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Symport, Transport" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 52.9;pituitary gland: 25.3" "Group enriched" "Detected in some" 5 "Excitatory neurons: 60.6;Inhibitory neurons: 59.4" "Cancer enriched" "Detected in some" 9 "melanoma: 17.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "SK-MEL-30: 36.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008043, HPA008044" Enhanced Approved Mitochondria NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "HPA008043: , HPA008044: AB_1857192" "unprognostic (1.13e-1)" "unprognostic (1.37e-3)" "unprognostic (5.52e-3)" "unprognostic (3.00e-2)" "unprognostic (1.17e-1)" "unprognostic (4.88e-2)" "unprognostic (6.11e-3)" "unprognostic (3.87e-3)" "unprognostic (1.70e-2)" "unprognostic (1.80e-1)" "unprognostic (1.68e-2)" "unprognostic (2.94e-1)" "unprognostic (1.89e-2)" "unprognostic (1.73e-2)" "unprognostic (9.76e-2)" "unprognostic (1.38e-3)" "unprognostic (1.68e-3)" 0.4 5.9 21.6 0.2 26.3 0.1 0.3 1.2 52.9 0.1 0.0 0.3 0.0 0.1 1.0 0.4 0.1 0.1 0.1 20.1 9.6 1.3 0.0 0.1 0.0 13.7 8.2 0.0 1.4 8.8 25.3 0.8 10.5 0.1 0.1 6.0 0.6 0.1 0.1 6.2 0.1 0.1 0.0 0.0 0.7 1.8 24.8 0.0 0.3 0.1 0.0 0.1 0.1 15.7 0.0 1.5 0.0 0.0 0.0 0.0 0.0 5.5 0.5 2.1 0.2 0.0 0.0 0.0 0.3 0.2 0.0 0.2 0.0 0.0 1.9 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 1.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.9 0.8 6.2 1.9 36.0 1.0 0.9 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.0 7.1 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.6 26.3 1.2 52.9 20.1 9.6 13.7 8.2 10.5 0.0 24.8 15.7 0.0 0.0 0.0 2.6 0.0 0.5 0.0 0.1 0.0 5.1 0.2 0.4 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.1 1.9 0.0 1.2 0.0 0.0 0.5 0.0 0.0 60.6 0.0 0.5 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 59.4 0.0 4.1 0.0 0.0 0.7 0.0 0.0 10.6 3.7 0.0 0.7 0.0 4.5 2.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.8 0.0 0.7 0.4 0.0 1.8 0.0 0.4 0.1 0.0 0.0 0.0 0.0 SLCO3A1 "OATP-D, OATP3A1, SLC21A11" ENSG00000176463 "Solute carrier organic anion transporter family member 3A1" Q9UIG8 15 91853708-92172435 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 39.5" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 625.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 63.1;HaCaT: 95.5;HMC-1: 55.3;RPMI-8226: 44.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066327 Approved NA NA "Cluster 10: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA066327: AB_2732743" "unprognostic (1.05e-3)" "prognostic favorable (8.61e-4)" "unprognostic (5.40e-2)" "prognostic unfavorable (6.57e-6)" "unprognostic (1.03e-1)" "unprognostic (7.39e-2)" "unprognostic (2.16e-1)" "unprognostic (1.57e-1)" "unprognostic (2.52e-1)" "unprognostic (1.84e-1)" "unprognostic (1.42e-2)" "unprognostic (1.49e-2)" "unprognostic (2.64e-2)" "unprognostic (3.06e-2)" "unprognostic (1.86e-1)" "unprognostic (7.17e-2)" "unprognostic (1.62e-2)" 11.7 6.2 19.3 6.8 29.5 9.6 8.6 33.7 23.0 8.4 24.1 4.0 1.8 5.3 3.3 10.6 6.9 6.3 26.4 20.3 20.2 10.6 2.9 13.8 6.3 30.2 29.6 4.2 3.0 15.7 6.7 1.0 27.8 4.3 3.4 1.5 4.7 6.2 5.8 15.7 4.2 5.0 22.5 11.1 4.6 17.9 26.1 2.6 10.6 9.6 6.2 8.6 10.8 39.5 10.1 12.3 13.9 0.2 20.9 12.6 0.2 4.0 3.4 1.6 0.4 0.0 63.1 12.1 5.3 1.3 9.1 95.5 2.7 6.3 0.2 8.8 0.4 27.8 20.9 0.0 0.9 0.6 55.3 5.7 6.7 2.9 7.3 5.4 0.0 3.6 0.0 0.1 0.0 1.8 0.0 5.1 3.7 0.2 1.7 0.0 1.1 44.0 13.4 10.0 2.0 3.3 10.5 0.9 0.1 2.0 0.1 8.5 0.0 3.3 4.7 0.0 10.3 25.5 16.0 11.7 4.2 16.9 6.0 4.3 2.4 6.9 1.4 2.0 1.1 0.2 1.5 1.7 1.6 0.0 0.5 0.6 7.5 0.3 1.7 0.0 2.7 0.6 19.3 29.5 33.7 23.0 20.3 20.2 30.2 29.6 27.8 22.5 26.1 39.5 53.5 48.1 32.0 17.0 4.3 39.0 29.3 14.2 22.8 28.1 3.1 13.0 44.0 24.3 16.4 51.5 4.2 0.0 33.1 6.2 1.9 26.6 105.6 15.8 29.0 26.2 37.8 6.1 89.5 8.7 0.1 22.9 0.5 36.2 22.8 94.9 34.6 0.8 4.6 0.0 149.4 7.2 8.2 24.7 95.2 38.5 5.0 34.0 10.6 56.2 43.6 5.2 25.7 20.6 625.8 8.4 11.1 3.0 17.3 41.5 0.0 0.4 22.1 3.1 39.5 17.4 62.0 69.5 11.9 22.6 60.1 0.0 23.3 0.8 7.9 38.2 SMAP2 SMAP1L ENSG00000084070 "Small ArfGAP2" Q8WU79 1 40344850-40423326 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 216.3" "Cell type enhanced" "Detected in all" "B-cells: 338.4;dendritic cells: 258.0;Kupffer cells: 284.4;Macrophages: 256.8;monocytes: 291.7;Plasma cells: 224.4;T-cells: 199.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 177.1;THP-1: 302.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021466, HPA024424" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 24: Non-specific - Transcription regulation" Cytosol Nucleoplasm "HPA021466: AB_2239737, HPA024424: AB_1857259" "unprognostic (1.65e-1)" "prognostic favorable (6.55e-4)" "unprognostic (7.17e-2)" "unprognostic (1.40e-3)" "unprognostic (4.32e-1)" "prognostic favorable (5.34e-5)" "prognostic unfavorable (2.53e-4)" "unprognostic (9.05e-2)" "unprognostic (2.27e-1)" "unprognostic (2.24e-1)" "unprognostic (4.00e-3)" "unprognostic (2.65e-1)" "unprognostic (1.02e-2)" "unprognostic (1.88e-2)" "unprognostic (5.45e-2)" "unprognostic (6.23e-2)" "unprognostic (1.24e-1)" 65.3 24.0 44.2 136.7 50.7 80.9 33.3 35.7 54.3 43.9 33.8 33.5 17.5 17.9 14.1 26.2 30.7 46.3 17.2 52.1 48.2 19.2 73.5 58.4 205.8 41.8 41.1 17.1 23.8 27.4 43.9 38.0 42.9 20.0 32.1 48.5 29.5 19.0 30.0 33.3 99.2 40.1 38.3 216.3 41.8 17.0 48.0 158.3 19.2 21.2 199.5 52.2 19.3 47.2 25.1 9.3 22.0 22.2 31.4 60.0 12.2 38.4 34.7 38.9 37.9 11.7 16.8 93.1 18.4 34.4 16.0 10.2 41.1 29.4 53.3 177.1 34.8 51.7 14.2 25.5 28.1 54.3 153.7 51.7 24.3 50.4 21.6 19.1 22.4 71.6 94.9 95.2 47.0 16.8 79.3 51.2 13.4 24.7 84.7 30.3 20.4 96.3 18.9 28.9 37.1 17.1 18.1 46.1 29.9 16.8 14.8 302.3 12.4 42.8 17.6 40.2 29.9 31.3 37.1 75.9 38.8 53.1 28.2 12.4 87.7 102.0 14.5 153.8 18.2 43.7 23.3 22.1 49.3 58.6 32.4 30.1 195.4 31.6 195.8 9.3 35.5 52.1 44.2 50.7 35.7 54.3 52.1 48.2 41.8 41.1 42.9 38.3 48.0 47.2 12.8 25.6 28.4 10.1 338.4 18.0 11.4 8.5 4.0 34.7 17.5 13.6 15.3 30.0 24.5 7.3 22.9 5.5 258.0 11.0 5.9 12.6 12.7 78.2 15.8 18.7 9.5 66.7 75.7 18.7 9.6 17.1 26.0 25.0 28.4 10.4 38.6 66.3 43.5 26.9 52.4 9.8 12.2 284.4 140.1 19.5 5.3 256.8 28.4 89.9 291.7 15.0 129.8 54.8 33.6 17.1 8.9 4.9 224.4 9.6 10.0 9.1 70.2 25.6 32.9 12.8 27.9 15.9 11.6 12.7 17.8 4.1 199.9 14.6 9.5 14.6 SMC2 "CAP-E, hCAP-E, SMC2L1" ENSG00000136824 "Structural maintenance of chromosomes 2" O95347 9 104094260-104141419 "Predicted intracellular proteins" "Cell cycle, Cell division, DNA condensation, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 25.7" "Cell type enhanced" "Detected in all" "Endometrial ciliated cells: 114.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071309 Approved Supported Nucleoplasm,Nucleoli Yes No 26000 "Cluster 44: Non-specific - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Nucleoli "HPA071309: AB_2686385" "unprognostic (1.51e-1)" "unprognostic (2.01e-3)" "unprognostic (2.26e-2)" "unprognostic (2.23e-2)" "unprognostic (3.04e-1)" "unprognostic (1.05e-1)" "unprognostic (5.57e-3)" "unprognostic (2.59e-3)" "unprognostic (1.47e-2)" "unprognostic (4.35e-1)" "unprognostic (1.24e-2)" "unprognostic (1.01e-1)" "unprognostic (5.56e-3)" "unprognostic (8.02e-3)" "unprognostic (1.65e-1)" "unprognostic (1.12e-1)" "unprognostic (1.32e-2)" 5.2 4.1 2.8 11.3 4.0 18.4 6.6 4.4 3.3 7.5 1.3 8.2 7.5 6.0 2.6 7.3 4.7 4.0 7.9 2.2 4.0 6.3 4.7 4.5 16.0 4.9 3.7 4.7 3.5 5.7 1.5 6.9 4.1 4.2 8.8 5.6 3.1 4.7 2.2 7.4 7.6 5.4 3.5 7.2 6.1 12.0 3.5 25.7 7.6 5.4 15.9 4.9 3.2 5.0 59.3 45.0 49.4 45.9 10.3 14.9 46.2 53.5 25.4 46.9 39.4 39.3 44.9 112.6 25.2 27.7 40.5 97.6 72.3 34.8 63.2 71.6 30.3 67.9 68.8 25.5 2.7 41.5 65.6 9.8 7.0 63.7 25.7 15.9 33.7 71.2 55.8 89.8 43.0 28.9 109.1 21.3 42.9 47.6 34.8 72.0 141.3 42.2 20.1 21.1 46.5 35.9 63.8 29.6 15.5 20.5 59.5 28.0 27.1 56.8 59.1 79.3 67.9 32.6 118.2 64.6 36.8 59.8 70.3 15.0 2.2 2.5 4.8 5.9 5.4 7.3 4.4 4.8 2.6 7.9 5.0 5.8 0.3 7.0 7.4 4.4 6.0 2.4 2.8 4.0 4.4 3.3 2.2 4.0 4.9 3.7 4.1 3.5 3.5 5.0 19.6 25.6 11.9 6.5 19.9 27.3 16.4 27.6 11.4 39.7 16.6 19.3 45.1 7.2 17.8 16.5 8.4 54.3 15.2 13.7 35.2 18.9 40.0 114.6 21.6 21.4 4.9 95.3 10.2 20.4 93.8 20.2 13.3 16.0 22.2 40.4 21.0 7.6 44.3 28.6 15.5 14.6 26.4 19.8 19.8 24.7 18.6 22.9 7.2 7.5 19.8 15.6 22.6 5.5 18.4 15.6 6.3 12.4 40.9 7.3 10.3 15.0 12.0 19.1 13.1 25.1 37.7 84.5 93.5 27.4 23.2 25.9 18.1 28.1 35.0 14.2 SMIM22 CASIMO1 ENSG00000267795 "Small integral membrane protein 22" K7EJ46 16 4788397-4796491 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 193.6;pancreas: 154.3;salivary gland: 147.2;stomach 1: 201.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 2005.0;Intestinal goblet cells: 1223.5;Paneth cells: 1462.9;Proximal enterocytes: 1685.8;Respiratory ciliated cells: 686.7;Undifferentiated cells: 775.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 7 "CAPAN-2: 261.7;OE19: 247.3;RT4: 89.8;SCLC-21H: 70.7;SK-BR-3: 201.2" "Low region specificity" "Detected in many" HPA077331 Approved Nucleoplasm,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Cytosol "HPA077331: AB_2686834" "unprognostic (6.55e-2)" "unprognostic (4.12e-2)" "unprognostic (4.84e-2)" "unprognostic (3.69e-3)" "unprognostic (7.82e-2)" "unprognostic (3.84e-2)" "unprognostic (4.63e-2)" "unprognostic (2.67e-2)" "unprognostic (6.20e-2)" "unprognostic (3.27e-1)" "unprognostic (2.41e-2)" "unprognostic (1.49e-1)" "unprognostic (1.59e-2)" "unprognostic (2.60e-1)" "unprognostic (1.25e-1)" "unprognostic (7.61e-2)" "unprognostic (1.73e-3)" 1.2 0.3 0.1 14.6 1.2 3.5 48.2 4.6 2.0 45.4 0.0 193.6 129.6 8.9 50.4 10.3 77.3 33.3 0.5 0.5 0.4 42.0 1.4 24.1 0.6 2.6 0.9 0.5 154.3 0.1 48.9 2.0 2.1 42.6 122.7 1.5 147.2 36.3 0.2 10.4 128.4 6.3 0.8 0.2 201.7 33.8 2.6 0.2 1.1 0.0 2.7 46.1 6.5 3.1 0.2 0.0 0.1 0.6 0.0 0.0 1.9 0.3 0.1 0.1 0.1 0.6 261.7 0.3 7.3 0.0 0.3 1.3 0.1 0.0 0.1 0.4 1.9 0.1 5.8 0.9 0.1 0.7 0.3 0.2 1.4 0.0 0.0 0.2 0.1 0.4 0.0 0.6 0.0 1.9 0.1 0.6 0.8 247.3 0.0 0.8 0.3 23.6 1.5 89.8 70.7 0.8 0.5 201.2 0.0 0.5 15.2 0.0 0.0 0.6 0.8 1.1 0.1 0.2 0.6 0.9 0.0 0.7 0.6 1.2 0.3 0.4 0.3 0.1 0.1 0.1 0.3 0.1 0.0 0.4 0.3 0.1 0.9 0.3 0.1 0.4 0.1 0.1 0.1 1.2 4.6 2.0 0.5 0.4 2.6 0.9 2.1 0.8 2.6 3.1 1.4 48.1 117.7 0.0 5.8 2.2 22.7 92.7 0.0 4.2 363.3 267.5 0.5 183.0 154.9 250.1 0.0 3.9 3.0 2005.0 25.4 259.8 40.1 430.4 26.5 4.4 470.3 0.0 0.5 381.9 0.4 4.7 438.8 258.3 18.4 0.1 0.4 0.2 0.4 1.7 0.3 1223.5 152.5 0.0 0.8 107.3 0.6 4.2 23.2 0.0 5.3 0.6 0.0 0.0 1.3 539.9 1462.9 1.2 1.0 29.5 1685.8 99.4 686.7 4.2 0.0 0.0 15.9 38.6 0.6 2.3 2.3 3.7 6.6 0.2 775.6 148.6 SOAT1 "ACAT, SOAT, STAT" ENSG00000057252 "Sterol O-acyltransferase 1" P35610 1 179293714-179358680 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Acyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "adrenal gland: 165.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009533, HPA047171" Enhanced Enhanced "Endoplasmic reticulum" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 4: Macrophages - Innate immune response" "Endoplasmic reticulum" "CAB009533: AB_633499, HPA047171: AB_2679967" "unprognostic (3.29e-2)" "unprognostic (7.60e-2)" "unprognostic (1.11e-1)" "unprognostic (3.21e-2)" "unprognostic (2.83e-1)" "unprognostic (1.81e-3)" "unprognostic (7.81e-3)" "unprognostic (3.29e-1)" "unprognostic (9.00e-2)" "unprognostic (9.84e-2)" "unprognostic (1.06e-1)" "unprognostic (5.45e-3)" "unprognostic (7.02e-3)" "unprognostic (4.67e-3)" "unprognostic (9.64e-2)" "unprognostic (4.67e-2)" "unprognostic (1.82e-1)" 14.6 165.3 4.2 18.1 5.7 17.5 8.2 5.5 6.6 13.7 9.0 13.0 12.2 11.7 6.6 4.8 17.9 20.5 5.4 3.3 6.8 12.7 14.1 20.9 15.1 10.1 6.1 10.7 27.0 13.4 6.3 19.1 8.0 27.7 14.8 10.3 39.4 9.3 4.0 5.7 12.7 16.5 8.0 15.1 16.3 11.0 6.7 8.1 9.2 3.7 13.1 11.7 4.5 12.8 74.6 34.1 27.7 41.0 104.7 56.6 147.3 35.1 61.7 76.2 88.3 35.2 82.6 42.0 53.9 64.4 92.6 26.8 88.6 20.9 81.8 48.0 18.2 19.5 26.7 36.9 42.9 33.5 7.5 45.4 13.3 89.2 75.8 32.1 33.3 50.5 42.7 21.0 120.0 15.9 35.9 10.8 13.4 11.8 11.2 44.4 35.8 24.4 66.1 45.9 8.4 21.5 54.3 22.9 20.1 32.3 24.0 22.8 31.9 89.8 43.1 99.5 78.2 29.4 115.3 35.5 35.7 17.9 170.6 55.4 53.4 1.6 26.4 34.2 25.0 12.9 24.0 24.8 48.9 10.4 23.0 23.3 39.3 37.9 23.7 8.8 33.2 32.5 4.2 5.7 5.5 6.6 3.3 6.8 10.1 6.1 8.0 8.0 6.7 12.8 14.9 22.4 33.4 11.4 16.0 9.9 10.1 11.3 8.0 7.3 7.2 4.6 8.5 30.0 14.5 20.2 14.6 17.6 21.2 16.0 1.9 42.5 29.5 34.9 32.8 16.0 59.9 9.0 12.1 25.0 51.6 21.3 18.3 34.5 14.0 9.2 15.4 24.2 70.3 6.7 15.0 25.5 22.4 77.4 41.9 14.5 32.6 74.9 23.2 29.0 55.4 7.6 19.6 10.6 7.3 20.3 13.3 25.9 17.7 26.7 8.7 14.9 46.2 14.5 26.3 9.2 13.5 6.8 9.7 5.0 5.3 8.8 24.8 44.3 15.5 8.5 SOX5 "L-SOX5, MGC35153" ENSG00000134532 "SRY-box transcription factor 5" P35711 12 23529504-24562544 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 32.3" "Cell type enhanced" "Detected in many" "Astrocytes: 1531.5;Excitatory neurons: 615.9;Inhibitory neurons: 717.3;Oligodendrocyte precursor cells: 1437.1" "Cancer enhanced" "Detected in many" "melanoma: 3.3" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "memory B-cell: 1.5;naive B-cell: 1.3" "Lineage enriched" "Detected in single" 5 "B-cells: 1.5" "Cell line enhanced" "Detected in many" "AF22: 17.3;Daudi: 18.3;HDLM-2: 38.3;K-562: 17.0;WM-115: 14.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060499 Supported Nucleoplasm NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 78: Testis - Spermatogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA060499: AB_2684294" "unprognostic (9.11e-4)" "unprognostic (4.64e-3)" "unprognostic (3.23e-1)" "unprognostic (6.83e-2)" "unprognostic (1.67e-1)" "unprognostic (1.10e-1)" "unprognostic (1.09e-1)" "unprognostic (1.03e-3)" "unprognostic (1.36e-1)" "unprognostic (8.40e-2)" "unprognostic (1.70e-4)" "unprognostic (6.95e-2)" "unprognostic (4.53e-4)" "unprognostic (3.12e-3)" "unprognostic (2.37e-1)" "unprognostic (9.59e-2)" "unprognostic (2.75e-2)" 5.8 1.1 6.3 1.7 9.6 0.4 1.5 0.4 10.3 6.9 0.0 1.3 0.7 5.0 1.2 1.2 3.6 3.0 2.4 6.4 7.6 1.8 11.1 2.7 3.7 2.9 5.8 7.7 1.1 0.4 0.4 8.8 5.6 2.1 1.2 3.7 3.2 3.1 0.6 6.3 1.1 2.7 3.1 1.3 1.1 32.3 6.8 0.6 2.0 1.7 3.1 1.3 0.6 5.0 0.2 0.2 17.3 0.0 9.6 5.1 0.0 0.2 0.0 0.2 0.5 3.1 0.1 18.3 0.8 0.0 0.0 0.2 9.9 0.0 0.3 38.3 2.4 3.9 0.1 8.4 6.6 0.1 0.2 2.7 0.0 0.9 0.0 2.2 0.0 0.6 17.0 0.8 0.3 0.0 7.1 0.1 5.5 0.1 0.0 0.0 0.3 0.0 0.1 0.1 0.8 0.8 0.0 0.0 6.7 4.3 0.3 3.6 0.0 0.3 2.1 0.0 1.7 0.4 0.0 1.1 4.0 0.1 14.4 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.1 6.3 9.6 0.4 10.3 6.4 7.6 2.9 5.8 5.6 3.1 6.8 5.0 4.5 6.4 11.0 1531.5 3.7 13.3 0.1 0.0 1.8 11.9 1.0 1.3 4.0 1.5 3.1 3.7 0.0 0.1 0.0 0.0 0.0 0.2 198.7 18.7 55.7 4.0 5.4 0.4 615.9 0.0 0.2 11.3 1.5 21.2 1.3 13.3 3.6 22.0 0.3 0.0 717.3 0.0 0.0 0.8 1.9 208.6 10.2 0.8 12.4 279.2 5.7 17.9 0.0 1437.1 24.4 0.0 0.0 6.8 1.2 0.1 0.4 0.6 13.8 2.6 19.7 2.8 24.7 97.0 1.4 0.5 12.1 0.3 0.7 0.2 0.2 0.2 SOX6 ENSG00000110693 "SRY-box transcription factor 6" P35712 11 15966449-16739591 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 26.9" "Cell type enhanced" "Detected in many" "Astrocytes: 308.9;Early spermatids: 256.8;Inhibitory neurons: 481.0;Oligodendrocyte precursor cells: 1687.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 20 "neutrophil: 2.0" "Lineage enriched" "Detected in single" 20 "granulocytes: 2.0" "Cell line enhanced" "Detected in some" "CACO-2: 5.7;HAP1: 4.4;hTCEpi: 5.0;SK-MEL-30: 4.9;WM-115: 18.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001923, HPA003908" Enhanced Supported Nucleoplasm NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm "HPA001923: AB_1080065, HPA003908: AB_1080063" "unprognostic (3.40e-2)" "unprognostic (1.70e-1)" "unprognostic (1.20e-1)" "unprognostic (1.68e-1)" "unprognostic (4.17e-3)" "unprognostic (1.05e-2)" "unprognostic (6.47e-3)" "unprognostic (1.25e-2)" "unprognostic (1.31e-1)" "unprognostic (7.89e-4)" "unprognostic (9.08e-2)" "unprognostic (7.37e-3)" "prognostic favorable (6.47e-12)" "unprognostic (9.90e-2)" "unprognostic (5.02e-2)" "unprognostic (1.15e-1)" "unprognostic (3.04e-2)" 1.8 1.3 5.4 0.4 5.9 26.9 0.7 2.6 4.7 1.7 5.5 1.2 6.5 0.6 2.0 2.1 4.0 2.6 3.0 4.0 7.2 11.1 4.8 0.8 0.1 7.2 7.8 0.7 6.8 0.1 2.9 2.5 6.0 0.4 1.3 3.2 0.5 0.6 9.3 5.8 11.0 0.5 7.7 0.5 1.0 14.4 4.1 1.6 3.4 5.9 0.2 0.8 0.8 6.8 0.0 0.7 3.9 3.7 0.0 0.0 0.0 0.3 1.3 0.1 0.1 5.7 0.0 0.0 3.6 0.0 0.0 0.1 4.4 1.1 0.0 0.0 0.5 0.0 0.0 0.3 0.6 0.0 0.0 0.0 5.0 0.0 0.1 0.0 0.0 0.0 2.2 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.8 0.0 1.8 0.0 0.0 0.1 0.4 0.0 4.9 0.5 0.0 0.0 0.0 2.6 2.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 18.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 5.4 5.9 2.6 4.7 4.0 7.2 7.2 7.8 6.0 7.7 4.1 6.8 2.7 3.2 6.3 308.9 1.0 40.1 5.8 6.8 66.6 26.3 3.7 2.5 21.6 54.3 3.8 36.8 10.4 1.3 0.1 1.4 9.8 19.8 256.8 29.4 5.3 4.8 7.8 126.7 2.8 3.7 0.6 14.5 2.0 27.8 0.0 1.6 2.2 7.5 1.1 0.0 481.0 6.6 0.0 2.9 3.2 70.1 3.4 1.4 35.6 21.5 0.0 48.4 0.0 1687.9 8.9 5.5 20.3 2.2 0.1 3.2 99.8 27.1 8.3 4.3 0.0 26.2 14.6 22.1 4.5 32.7 16.1 0.5 1.1 3.0 11.8 3.7 SOX8 ENSG00000005513 "SRY-box transcription factor 8" P57073 16 981770-986979 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 127.4" "Group enriched" "Detected in some" 9 "Muller glia cells: 156.1;Oligodendrocyte precursor cells: 64.3;Oligodendrocytes: 66.0" "Cancer enriched" "Detected in many" 6 "glioma: 46.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "RH-30: 114.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041640, HPA058665" Enhanced Nucleoplasm No NA "Cluster 70: Brain - Nervous system development" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 5: Muller glia cells - Visual perception" Nucleoplasm "HPA041640: AB_10964357, HPA058665: AB_2683792" "unprognostic (1.40e-2)" "unprognostic (2.56e-3)" "unprognostic (1.59e-1)" "unprognostic (3.10e-2)" "unprognostic (4.58e-2)" "unprognostic (7.16e-3)" "unprognostic (6.05e-3)" "unprognostic (3.01e-2)" "unprognostic (2.53e-1)" "unprognostic (1.16e-1)" "unprognostic (4.53e-3)" "unprognostic (4.46e-2)" "unprognostic (1.20e-3)" "unprognostic (8.50e-2)" "unprognostic (6.18e-2)" "unprognostic (5.47e-1)" "unprognostic (9.09e-2)" 0.9 0.5 58.3 0.9 90.4 0.1 1.7 66.7 71.8 1.3 23.6 3.1 0.1 0.4 0.1 0.4 0.6 0.5 4.1 54.0 57.9 0.7 0.2 0.3 2.0 73.6 79.8 0.3 1.0 0.1 1.2 0.4 64.9 1.2 0.6 14.8 8.3 0.4 0.8 5.4 1.8 0.2 58.7 1.0 0.9 2.5 71.2 0.4 0.5 0.6 2.3 1.4 1.6 127.4 0.0 0.6 2.2 21.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 1.3 0.0 0.0 0.4 5.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.1 0.0 0.0 0.0 3.3 1.8 0.2 0.0 114.7 4.5 0.0 0.0 0.0 0.0 0.1 0.0 4.1 0.4 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.9 0.3 0.4 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 58.3 90.4 66.7 71.8 54.0 57.9 73.6 79.8 64.9 58.7 71.2 127.4 1.5 0.0 0.0 10.1 0.2 0.4 0.5 0.0 0.0 1.8 8.7 10.4 1.2 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.5 0.0 0.0 0.6 2.6 0.0 0.0 4.6 0.2 0.1 1.9 0.0 0.1 0.0 0.0 0.7 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.3 0.5 3.4 0.3 1.8 3.7 0.6 156.1 0.0 64.3 66.0 0.1 0.3 1.9 0.5 1.9 0.0 0.0 0.0 8.0 0.0 9.9 0.9 0.0 3.9 0.4 1.0 0.0 0.9 0.1 0.9 0.3 SPATA31D1 "FAM75D1, FLJ46321" ENSG00000214929 "SPATA31 subfamily D member 1" Q6ZQQ2 9 81988772-81995253 "Predicted membrane proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 112 "testis: 11.1" "Cell type enriched" "Detected in some" 4 "Early spermatids: 10.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047897 Uncertain NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 29: Early spermatids - Spermatogenesis" "HPA047897: AB_2680204" "unprognostic (1.25e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SPATA5L1 "FLJ12286, MGC5347" ENSG00000171763 "Spermatogenesis associated 5 like 1" Q9BVQ7 15 45402336-45421415 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043679 Uncertain Approved Nucleoplasm,Nucleoli NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 59: Non-specific - Translation" "Cluster 24: NB-4 - Immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm Nucleoli "HPA043679: AB_10964179" "unprognostic (6.22e-2)" "unprognostic (3.34e-2)" "unprognostic (7.03e-2)" "unprognostic (1.57e-2)" "unprognostic (9.67e-2)" "unprognostic (6.85e-2)" "unprognostic (2.46e-2)" "unprognostic (3.13e-2)" "unprognostic (3.69e-2)" "unprognostic (3.69e-1)" "unprognostic (4.97e-2)" "prognostic unfavorable (7.88e-4)" "unprognostic (5.40e-2)" "unprognostic (2.98e-2)" "unprognostic (2.55e-2)" "unprognostic (2.72e-2)" "unprognostic (4.80e-2)" 4.5 4.9 4.7 4.6 5.1 6.3 4.5 5.5 6.2 5.5 4.4 5.2 5.9 4.4 3.9 10.0 5.0 2.7 5.7 4.9 5.0 6.0 7.5 3.3 4.6 4.9 4.8 6.1 5.8 4.3 3.1 5.2 5.0 4.2 4.8 4.6 4.4 3.9 8.9 7.4 5.5 4.4 5.0 4.5 4.5 3.4 5.2 4.9 5.3 5.4 5.0 5.4 6.0 5.6 10.0 6.3 9.9 7.3 8.0 7.8 12.0 8.7 7.9 9.3 9.0 17.3 6.3 7.3 9.5 5.8 16.9 22.5 14.8 10.9 10.3 10.0 8.4 9.5 11.2 13.6 9.0 12.8 4.0 6.2 12.2 7.7 10.1 10.6 7.4 9.4 15.6 11.4 10.5 6.7 8.9 24.5 7.1 24.8 9.7 9.8 13.9 6.8 11.7 9.8 13.5 6.9 7.2 15.5 8.4 11.7 13.7 23.1 4.7 4.5 6.9 27.8 18.8 9.7 20.8 11.3 11.6 20.8 8.3 0.0 0.9 1.2 1.1 0.7 0.4 0.6 0.7 1.5 0.9 0.7 0.6 0.9 1.1 1.1 1.9 1.0 0.8 0.2 4.7 5.1 5.5 6.2 4.9 5.0 4.9 4.8 5.0 5.0 5.2 5.6 4.7 0.0 1.1 7.2 8.9 5.0 8.9 4.6 5.2 7.9 3.7 2.4 6.9 7.2 5.2 3.7 16.7 12.2 7.3 5.4 3.9 6.2 20.6 6.2 5.4 6.3 3.6 2.5 11.0 7.3 11.9 5.2 9.2 8.4 4.5 8.6 1.1 5.7 8.0 6.7 10.1 6.3 0.0 3.7 7.6 7.1 7.8 7.7 3.6 6.5 7.7 5.0 2.1 16.6 14.6 5.5 3.1 3.8 8.5 6.2 9.2 5.7 2.4 6.5 0.0 4.1 4.1 6.2 5.6 10.4 6.8 6.7 5.8 6.1 7.3 8.2 SPC24 "FLJ90806, SPBC24" ENSG00000161888 "SPC24 component of NDC80 kinetochore complex" Q8NBT2 19 11131520-11155808 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 26.0;lymphoid tissue: 14.7" "Cell type enhanced" "Detected in many" "Erythroid cells: 35.0;Extravillous trophoblasts: 15.5;Hofbauer cells: 14.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA051234 Approved Supported Nucleoplasm,Nucleoli NA Yes "Cluster 40: NK-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Nucleoli "HPA051234: AB_2681397" "unprognostic (1.57e-1)" "prognostic favorable (3.59e-4)" "unprognostic (6.79e-2)" "unprognostic (1.07e-3)" "unprognostic (4.04e-1)" "unprognostic (2.98e-2)" "prognostic unfavorable (1.46e-4)" "unprognostic (1.21e-2)" "unprognostic (1.69e-2)" "unprognostic (1.12e-2)" "prognostic unfavorable (1.22e-4)" "unprognostic (6.12e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.62e-2)" "unprognostic (3.52e-2)" "unprognostic (2.25e-1)" "unprognostic (8.82e-2)" 1.9 1.7 1.3 4.8 1.5 26.0 1.2 3.9 2.1 2.1 1.7 4.7 4.5 2.7 0.8 5.0 1.3 2.3 2.7 1.6 1.5 0.8 1.6 1.6 6.3 1.1 0.8 1.3 1.1 0.4 0.4 3.2 1.3 1.6 4.3 1.2 1.3 2.0 4.0 3.9 4.1 8.1 0.5 3.1 2.9 4.3 1.4 14.7 0.9 1.1 6.5 2.5 2.0 2.4 73.6 26.9 36.9 30.1 5.0 9.7 16.6 42.3 15.7 38.6 43.6 28.4 24.6 58.2 46.0 18.5 22.8 38.8 29.0 30.3 28.7 30.9 24.9 78.5 68.9 43.2 1.1 55.5 33.7 1.9 1.1 27.8 12.8 10.0 34.7 62.3 42.8 118.3 27.6 48.7 76.4 32.9 25.5 19.8 43.9 59.8 56.7 18.6 11.2 23.8 38.4 27.2 37.0 22.4 9.6 17.5 22.0 19.8 33.2 36.8 38.3 49.6 51.2 70.5 39.8 55.6 26.9 53.9 30.5 1.9 0.4 0.4 0.5 0.5 0.4 0.8 0.9 1.5 0.2 0.7 0.9 0.6 2.2 2.0 0.5 0.5 1.7 0.3 1.3 1.5 3.9 2.1 1.6 1.5 1.1 0.8 1.3 0.5 1.4 2.4 0.2 0.0 0.5 0.3 1.5 1.1 1.2 1.3 0.0 0.0 1.0 0.4 9.0 1.5 0.8 5.5 6.2 10.0 0.9 2.8 0.0 0.2 0.3 1.0 2.2 2.2 2.4 35.0 0.3 0.0 15.5 3.5 3.6 1.8 5.7 6.5 4.6 0.7 14.0 0.0 0.3 2.6 0.0 3.0 2.5 3.0 0.6 1.0 0.0 1.0 0.0 2.1 2.1 0.5 0.3 0.3 0.0 0.4 6.3 0.3 0.7 0.6 0.2 0.6 0.0 1.3 2.4 6.9 10.8 2.1 0.3 2.1 2.2 0.5 6.6 1.2 SPINT2 "HAI-2, Kop" ENSG00000167642 "Serine peptidase inhibitor, Kunitz type 2" O43291 19 38244035-38292615 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 1371.3;Syncytiotrophoblasts: 1413.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 852.5;CAPAN-2: 1219.1;OE19: 1500.4;RPTEC TERT1: 896.7;SK-BR-3: 789.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011101, CAB018969" Approved Uncertain "Plasma membrane,Intermediate filaments,Cytosol" No NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 47: Cytotrophoblasts - Unknown function" "Plasma membrane, Intermediate filaments, Cytosol" "CAB018969: , HPA011101: AB_1079039" "unprognostic (5.13e-2)" "unprognostic (1.06e-3)" "unprognostic (1.40e-1)" "unprognostic (6.25e-2)" "unprognostic (1.13e-1)" "unprognostic (1.91e-2)" "unprognostic (2.23e-1)" "unprognostic (2.03e-2)" "unprognostic (3.51e-1)" "unprognostic (1.67e-2)" "unprognostic (2.89e-2)" "unprognostic (2.04e-1)" "prognostic favorable (3.41e-4)" "unprognostic (3.59e-1)" "unprognostic (1.32e-1)" "unprognostic (6.94e-2)" "unprognostic (2.68e-2)" 10.5 44.6 56.9 65.3 57.3 81.1 178.5 47.2 66.3 145.6 80.0 297.0 247.4 44.6 269.6 351.9 189.7 105.1 13.6 58.9 92.9 216.1 14.3 138.3 37.4 52.0 54.8 83.3 234.2 252.9 435.9 156.4 56.2 181.8 251.7 23.6 503.9 111.3 1.8 257.0 267.0 19.0 47.6 50.2 219.4 215.7 70.3 82.6 321.3 0.9 101.3 140.1 157.6 51.0 852.5 603.0 3.0 3.4 0.4 0.0 387.4 16.2 1.7 1.2 2.6 426.8 1219.1 6.7 65.8 4.6 1.2 274.6 42.7 587.0 1.4 7.9 51.7 159.4 15.3 0.9 0.9 1.5 0.8 0.1 662.5 0.7 278.6 71.5 2.0 144.2 4.0 0.4 1.0 652.8 25.6 2.8 60.4 1500.4 172.1 87.9 0.6 386.2 896.7 707.4 222.2 3.4 246.5 789.2 2.1 231.0 353.7 104.5 0.7 1.2 4.7 3.4 3.2 56.1 76.4 47.6 1.0 11.2 1.0 515.9 127.4 531.9 3.8 91.1 7.9 143.2 44.2 21.5 297.7 160.4 86.1 80.4 56.4 19.0 64.4 523.5 19.1 142.8 56.9 57.3 47.2 66.3 58.9 92.9 52.0 54.8 56.2 47.6 70.3 51.0 8.0 368.6 233.9 10.4 90.9 376.9 563.9 954.0 278.9 14.3 487.2 518.2 2.8 316.0 655.6 559.1 6.2 1371.3 79.5 1028.3 101.8 866.9 61.8 401.4 47.3 24.3 360.5 83.9 20.7 659.8 502.0 34.6 234.5 490.4 115.5 371.8 32.5 2.0 230.3 3.3 39.8 672.8 734.5 55.5 139.0 55.6 19.0 133.6 88.9 24.4 364.3 129.6 1.0 4.5 9.0 910.4 889.4 17.0 61.3 684.9 918.6 208.8 495.1 17.2 52.6 1.2 76.7 545.2 264.1 507.7 428.3 1413.2 42.6 3.4 582.2 989.6 SRGAP2C SRGAP2P1 ENSG00000171943 "SLIT-ROBO Rho GTPase activating protein 2C" P0DJJ0 1 121184811-121392874 "Predicted intracellular proteins" Neurogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 31.2" "Cell type enhanced" "Detected in many" "Microglial cells: 180.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "WM-115: 80.0" HPA078079 Approved Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 17: WM-115 - Nervous system development" "Cluster 41: Macrophages - Immune response" Cytosol "HPA078079: " "unprognostic (2.43e-1)" "unprognostic (6.66e-2)" "unprognostic (7.65e-3)" "unprognostic (1.48e-6)" "unprognostic (2.40e-2)" "unprognostic (1.11e-1)" "unprognostic (7.18e-4)" "unprognostic (6.10e-2)" "unprognostic (7.48e-2)" "unprognostic (2.32e-1)" "unprognostic (1.36e-2)" "unprognostic (2.89e-1)" "unprognostic (3.71e-7)" "unprognostic (4.90e-2)" "unprognostic (2.10e-1)" "unprognostic (1.70e-1)" "unprognostic (7.66e-2)" 8.3 6.5 11.1 3.7 13.2 7.2 5.7 31.2 12.5 5.8 3.9 6.5 2.1 5.4 2.2 4.3 5.0 4.6 5.8 11.7 11.8 7.1 4.7 7.3 4.6 16.1 12.3 6.8 2.2 13.7 3.3 8.0 17.6 3.6 2.8 3.5 3.0 4.6 2.8 15.5 3.6 6.0 16.6 10.7 3.2 1.5 12.4 4.2 3.9 10.7 3.4 4.6 5.5 21.9 11.1 14.1 30.7 6.8 23.1 20.1 16.8 12.3 9.8 10.2 13.2 0.2 11.0 7.0 10.8 16.8 7.3 5.9 11.0 8.9 13.4 9.2 11.2 10.0 24.5 11.1 13.3 6.8 11.4 15.2 8.9 13.1 16.6 11.6 24.5 4.3 9.3 12.8 7.6 6.6 4.3 8.6 9.7 3.5 6.7 6.2 35.9 6.2 9.7 6.5 5.9 3.8 21.2 7.5 38.6 15.8 9.5 19.8 21.9 19.1 18.7 28.9 18.1 7.3 5.6 4.2 16.7 13.7 80.0 0.3 3.4 0.6 1.1 2.8 0.7 0.9 1.3 1.2 2.5 0.9 0.6 0.8 3.2 0.6 5.3 2.4 1.3 0.9 11.1 13.2 31.2 12.5 11.7 11.8 16.1 12.3 17.6 16.6 12.4 21.9 39.9 54.5 11.5 5.2 14.4 0.0 5.6 0.0 6.2 14.2 5.8 6.7 4.3 15.7 5.0 11.0 2.1 5.5 15.5 1.2 1.9 10.9 1.0 11.7 15.4 34.6 2.4 29.7 42.0 5.0 24.8 15.9 5.1 6.4 6.3 7.8 55.3 8.7 19.9 0.0 62.6 2.7 0.0 64.2 0.0 2.1 19.6 41.6 0.0 180.8 39.6 8.4 18.6 35.2 27.4 7.2 1.4 25.6 10.7 5.0 0.5 1.0 8.7 4.3 32.9 20.2 14.5 10.1 10.8 12.5 0.0 2.5 12.6 7.0 2.0 4.5 STK32A "MGC22688, YANK1" ENSG00000169302 "Serine/threonine kinase 32A" Q8WU08 5 147234963-147387855 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 11.2;brain: 24.4" "Cell type enriched" "Detected in many" 19 "Oligodendrocyte precursor cells: 306.6" "Group enriched" "Detected in many" 5 "glioma: 4.3;melanoma: 11.9;thyroid cancer: 9.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "RT4: 13.6;SK-MEL-30: 48.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040236 Approved Centrosome NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 68: Oligodendrocytes - Mixed function" Centrosome "HPA040236: AB_10795416" "unprognostic (1.90e-1)" "unprognostic (4.71e-4)" "unprognostic (5.32e-2)" "unprognostic (3.49e-2)" "unprognostic (7.62e-2)" "unprognostic (6.82e-2)" "unprognostic (2.66e-2)" "unprognostic (2.96e-3)" "unprognostic (4.85e-2)" "unprognostic (2.36e-2)" "unprognostic (3.87e-1)" "unprognostic (8.38e-2)" "unprognostic (2.50e-3)" "unprognostic (5.53e-5)" "unprognostic (2.48e-1)" "unprognostic (3.20e-2)" "unprognostic (3.67e-3)" 1.3 11.2 5.9 0.6 9.5 0.0 1.2 13.2 3.1 1.0 1.0 2.3 0.5 0.5 2.6 0.3 0.8 1.5 1.0 3.5 14.4 3.4 0.1 1.2 0.0 11.7 24.4 2.5 2.6 0.1 8.1 0.1 17.0 1.0 0.3 2.6 0.9 0.8 0.2 3.7 0.7 0.4 10.4 0.3 1.2 1.0 14.0 0.1 8.7 0.5 0.0 1.7 1.0 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.5 0.0 1.4 0.0 0.0 0.0 0.1 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.5 0.0 1.1 0.0 0.0 0.2 4.4 13.6 1.2 0.5 0.0 0.0 48.6 0.2 0.0 0.0 0.1 0.0 0.5 0.7 0.4 1.0 0.2 0.0 1.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 9.5 13.2 3.1 3.5 14.4 11.7 24.4 17.0 10.4 14.0 10.1 0.2 0.0 2.6 8.5 0.0 1.5 0.2 1.4 0.0 1.8 1.3 0.5 0.5 0.0 1.0 1.8 0.0 0.0 0.0 0.1 1.9 1.8 6.9 0.2 0.5 0.1 0.0 0.0 4.6 2.7 0.0 2.7 0.0 0.7 0.0 4.2 0.0 0.0 0.1 0.0 5.2 0.0 2.0 0.0 1.0 10.5 0.9 0.2 16.0 0.0 0.0 4.0 0.0 306.6 0.7 5.5 0.0 4.1 0.0 0.3 0.0 4.1 0.2 1.0 0.0 5.4 0.5 0.0 0.1 0.0 0.3 0.1 0.1 1.4 0.0 0.6 STK39 "DCHT, SPAK" ENSG00000198648 "Serine/threonine kinase 39" Q9UEW8 2 167954020-168247595 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 159.9;Inhibitory neurons: 142.9;Oligodendrocyte precursor cells: 153.3;Oligodendrocytes: 359.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046022, HPA061803, HPA062802" Enhanced Supported Nucleoplasm,Vesicles,Cytosol NA NA 80000 "Cluster 35: T-regs - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "Vesicles, Cytosol" "CAB046022: AB_2196960, HPA061803: AB_2684616, HPA062802: AB_2684870" "prognostic favorable (3.96e-4)" "unprognostic (2.97e-2)" "unprognostic (4.40e-2)" "unprognostic (4.22e-2)" "unprognostic (4.36e-1)" "unprognostic (6.14e-2)" "prognostic unfavorable (5.67e-5)" "unprognostic (3.04e-2)" "unprognostic (8.86e-2)" "unprognostic (9.43e-2)" "unprognostic (3.20e-2)" "unprognostic (1.38e-1)" "unprognostic (2.06e-1)" "unprognostic (9.45e-2)" "unprognostic (8.61e-3)" "unprognostic (1.14e-1)" "unprognostic (6.20e-3)" 19.4 6.7 20.1 14.0 25.8 5.1 8.4 25.3 25.1 12.0 52.9 26.3 32.0 7.3 14.5 36.3 6.4 18.1 15.8 16.0 18.6 9.0 1.9 7.6 22.2 28.8 25.8 6.6 25.6 13.7 8.2 2.3 31.9 28.7 32.4 27.8 67.9 11.5 2.7 6.3 18.6 11.7 20.8 8.6 31.8 48.5 25.6 29.1 6.9 7.6 23.5 24.8 9.5 37.0 19.1 10.9 40.9 12.9 28.1 37.5 4.0 45.0 33.8 29.6 27.8 0.2 59.9 51.1 12.2 30.5 25.5 46.6 26.7 34.4 37.1 16.2 16.4 21.2 11.8 42.9 52.3 30.5 2.1 29.1 52.8 35.1 36.5 38.5 21.2 41.3 0.5 0.0 67.0 11.4 51.6 13.0 30.3 41.0 24.3 72.1 16.0 4.8 27.9 47.6 65.7 27.0 15.7 2.6 21.8 20.3 8.0 25.9 20.2 36.6 11.1 26.5 32.2 0.1 0.0 41.5 29.7 28.5 25.1 0.0 0.3 0.0 1.1 0.2 0.6 0.2 0.9 1.6 0.5 0.5 0.2 0.8 0.0 1.0 0.1 0.1 1.8 0.2 20.1 25.8 25.3 25.1 16.0 18.6 28.8 25.8 31.9 20.8 25.6 37.0 6.1 3.2 14.0 64.6 6.4 3.8 34.4 6.5 5.7 14.8 5.5 6.5 26.2 18.6 15.2 5.5 16.7 0.1 30.0 47.7 21.5 10.9 29.4 11.9 11.6 5.6 22.8 5.7 159.9 23.1 0.1 9.2 28.1 18.9 0.0 5.8 2.9 0.4 3.5 20.2 142.9 17.3 14.2 6.7 6.7 16.2 10.2 6.7 17.8 64.6 5.5 28.9 12.3 153.3 359.4 36.0 20.1 11.3 9.5 74.8 14.5 7.9 17.5 30.0 6.6 7.7 18.2 25.4 8.1 7.5 4.4 0.3 19.4 15.8 22.4 50.6 STK40 "MGC4796, SgK495" ENSG00000196182 "Serine/threonine kinase 40" Q8N2I9 1 36339624-36385924 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 116.7;Late spermatids: 236.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 25.2" "Group enriched" "Detected in all" 5 "granulocytes: 25.2;monocytes: 12.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008026 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 17: WM-115 - Nervous system development" "Cluster 31: Spermatids - Spermatogenesis" Cytosol Nucleoplasm "HPA008026: AB_1857603" "unprognostic (3.32e-1)" "unprognostic (3.00e-1)" "unprognostic (6.47e-2)" "unprognostic (4.55e-1)" "unprognostic (1.38e-1)" "unprognostic (4.43e-2)" "unprognostic (2.69e-3)" "unprognostic (6.09e-2)" "unprognostic (2.09e-1)" "unprognostic (5.96e-2)" "prognostic favorable (5.59e-4)" "unprognostic (1.19e-1)" "unprognostic (2.75e-2)" "unprognostic (7.06e-2)" "unprognostic (2.64e-1)" "unprognostic (1.07e-2)" "unprognostic (2.51e-2)" 33.3 15.5 17.4 23.1 17.0 15.2 24.6 16.6 19.9 24.3 14.1 44.8 13.5 23.6 8.1 43.8 24.7 20.4 42.7 17.5 17.6 33.5 45.3 36.4 24.3 24.8 19.0 40.3 45.7 21.8 30.1 13.5 20.6 28.5 12.7 7.5 32.0 23.1 125.2 38.8 23.7 20.0 19.9 35.4 35.5 52.5 20.1 15.6 25.3 39.6 21.4 41.7 26.7 19.8 17.4 7.4 36.6 38.3 25.3 14.7 20.5 17.2 23.1 20.3 21.8 41.3 24.2 73.0 13.8 16.1 21.5 17.1 33.5 7.4 14.9 32.0 26.4 47.7 7.5 53.3 25.1 28.1 60.9 13.3 27.7 15.6 8.2 10.9 12.9 55.2 59.7 25.7 12.9 27.0 29.3 37.1 23.5 31.2 10.2 33.3 24.9 49.1 12.7 19.2 44.6 22.7 13.2 20.5 58.5 23.1 13.9 32.7 21.6 12.7 26.5 37.7 38.3 26.6 16.2 61.3 66.3 24.3 42.8 1.2 3.8 6.8 3.1 8.6 3.6 2.8 2.1 2.2 3.5 2.9 1.2 1.8 25.2 2.1 12.0 3.3 1.3 3.5 17.4 17.0 16.6 19.9 17.5 17.6 24.8 19.0 20.6 19.9 20.1 19.8 10.7 12.8 15.3 11.8 22.0 61.3 54.0 9.4 16.5 11.8 28.3 15.4 25.3 8.6 11.1 11.0 4.2 6.5 15.8 34.8 17.6 21.2 116.7 23.9 11.2 15.2 23.4 7.8 24.8 31.6 10.7 19.2 33.1 36.5 13.3 4.9 14.3 23.7 24.7 10.1 17.3 15.5 12.2 23.3 69.5 236.8 23.0 32.2 30.2 21.5 19.2 4.9 18.6 7.5 12.3 28.5 16.3 33.4 17.0 57.1 6.2 14.9 25.6 10.5 26.3 20.6 18.6 14.9 11.1 28.7 75.4 57.2 17.3 17.6 15.1 51.3 STON1 "SBLF, stoned-b1" ENSG00000243244 "Stonin 1" Q9Y6Q2 2 48529383-48598513 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 42.0;Muller glia cells: 33.4;Sertoli cells: 26.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 15 "basophil: 1.9;neutrophil: 1.0" "Lineage enriched" "Detected in single" 19 "granulocytes: 1.9" "Cell line enhanced" "Detected in many" "ASC diff: 23.7;ASC TERT1: 28.6;HSkMC: 36.1;hTERT-RPE1: 17.0;SuSa: 19.6" "Low region specificity" "Detected in all" HPA005715 Uncertain NA NA "Cluster 10: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "HPA005715: AB_1080113" "unprognostic (1.61e-1)" "unprognostic (4.44e-1)" "unprognostic (7.97e-2)" "unprognostic (1.02e-4)" "unprognostic (1.54e-1)" "unprognostic (2.11e-1)" "unprognostic (1.35e-1)" "unprognostic (3.01e-2)" "unprognostic (8.99e-3)" "unprognostic (1.09e-1)" "unprognostic (1.76e-1)" "unprognostic (2.10e-2)" "prognostic unfavorable (4.69e-4)" "unprognostic (1.06e-2)" "unprognostic (2.50e-1)" "unprognostic (8.68e-2)" "unprognostic (2.49e-3)" 20.8 5.2 2.3 5.7 2.8 0.5 10.9 10.5 2.0 10.5 10.7 34.5 3.6 27.4 4.6 16.0 17.2 15.6 6.4 1.9 7.1 9.3 2.1 10.9 2.8 33.2 12.5 24.5 1.9 2.1 2.8 18.4 25.9 21.7 8.4 18.1 2.5 19.3 2.2 4.1 7.9 25.1 25.6 7.4 13.0 1.1 4.1 2.5 4.6 6.3 1.4 22.2 10.5 29.2 0.1 0.0 8.6 0.1 23.7 28.6 4.9 1.0 9.2 0.9 2.1 0.1 0.0 0.0 0.3 12.0 4.6 9.0 8.3 0.3 1.7 0.1 2.3 1.4 0.6 0.0 13.5 0.0 0.4 36.1 1.7 2.5 1.0 17.0 16.4 0.8 0.2 0.2 5.7 0.5 0.7 0.3 8.0 0.0 0.1 1.3 1.7 0.0 0.9 6.6 0.3 1.9 0.7 1.5 4.0 19.6 0.7 0.3 8.8 3.0 2.3 0.0 0.7 0.5 0.1 0.0 1.6 0.1 1.9 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 2.3 2.8 10.5 2.0 1.9 7.1 33.2 12.5 25.9 25.6 4.1 29.2 16.4 0.0 0.5 0.0 1.1 2.4 15.4 1.1 16.5 3.8 0.8 1.8 2.3 0.0 0.8 5.5 2.1 15.1 0.5 0.6 3.9 0.8 0.4 1.9 42.0 7.7 2.4 0.0 0.0 0.4 1.0 9.9 0.5 2.6 0.0 3.9 11.4 0.2 2.7 13.5 0.0 0.3 0.0 1.3 2.8 0.9 12.2 1.6 0.0 0.0 1.2 33.4 1.0 0.0 0.0 0.4 0.3 10.1 0.2 13.8 0.4 2.0 0.6 2.3 26.3 1.9 15.1 0.3 1.7 1.9 2.4 12.6 1.5 2.6 0.9 14.3 STRA8 ENSG00000146857 "Stimulated by retinoic acid 8" Q7Z7C7 7 135231979-135258492 "Predicted intracellular proteins" "Differentiation, DNA replication, Meiosis, Oogenesis, Spermatogenesis, Transcription, Transcription regulation" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "choroid plexus: 6.6" "Cell type enriched" "Detected in some" 6 "Spermatogonia: 10.8" "Cancer enhanced" "Detected in many" "renal cancer: 2.1" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.5;THP-1: 2.4;U-266/84: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA078044 Approved Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 43: THP-1 - Innate immune response" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Cytosol "HPA078044: " "unprognostic (2.84e-1)" "unprognostic (4.86e-2)" "unprognostic (3.89e-2)" "unprognostic (9.67e-4)" "unprognostic (1.21e-1)" "unprognostic (1.01e-1)" "unprognostic (1.02e-1)" "unprognostic (1.26e-3)" "unprognostic (1.25e-1)" "unprognostic (8.55e-3)" "unprognostic (1.45e-1)" "unprognostic (2.69e-1)" 0.1 0.0 0.6 0.0 0.5 0.0 0.0 0.3 0.5 0.0 6.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.3 0.3 0.0 0.1 0.0 0.6 0.5 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.1 0.0 0.3 0.0 0.0 0.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.1 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 2.4 0.1 0.1 0.0 0.0 0.0 0.2 1.5 0.1 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.5 0.3 0.5 1.0 0.3 0.6 0.5 0.6 0.3 0.6 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.8 10.8 0.0 0.0 0.8 0.0 0.0 0.0 0.0 SUSD2 "BK65A6.2, FLJ22778, W5C5" ENSG00000099994 "Sushi domain containing 2" Q9UGT4 22 24181487-24189106 "Predicted membrane proteins" Receptor "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 99.8" "Group enriched" "Detected in many" 6 "Alveolar cells type 1: 250.0;Alveolar cells type 2: 151.5;Proximal enterocytes: 154.9" "Cancer enhanced" "Detected in all" "testis cancer: 64.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 29 "SK-BR-3: 898.7" "Low region specificity" "Detected in all" HPA004117 Enhanced Approved "Plasma membrane" NA NA 6800000 "Cluster 19: Lung - Lung function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" "HPA004117: AB_1857674" "unprognostic (5.24e-3)" "unprognostic (1.60e-1)" "unprognostic (1.74e-1)" "unprognostic (7.30e-2)" "unprognostic (1.27e-2)" "unprognostic (5.40e-2)" "unprognostic (5.20e-2)" "unprognostic (1.89e-2)" "unprognostic (5.87e-2)" "unprognostic (1.20e-2)" "unprognostic (9.74e-3)" "unprognostic (8.97e-2)" "prognostic unfavorable (3.29e-5)" "unprognostic (2.72e-2)" "unprognostic (2.82e-2)" "unprognostic (1.88e-2)" "unprognostic (3.33e-3)" 12.1 9.6 4.9 1.9 2.8 0.2 9.5 1.7 5.8 13.6 2.2 4.8 12.8 9.8 0.5 2.8 15.0 1.8 12.5 1.6 5.3 32.6 2.9 99.8 2.2 22.9 6.9 5.4 4.3 1.5 7.1 3.6 26.5 5.6 1.0 0.1 4.7 5.6 2.2 28.2 34.6 3.4 6.8 3.6 6.3 3.2 13.2 0.8 17.8 1.4 1.3 5.4 11.0 10.0 5.1 10.4 0.1 0.0 18.8 24.3 0.8 2.4 0.1 0.1 0.0 7.8 0.6 1.4 21.5 0.5 0.4 1.4 0.1 0.5 0.0 0.6 0.3 0.0 0.4 30.6 8.0 0.0 0.3 21.5 0.4 0.1 6.2 0.0 0.1 0.0 0.5 0.3 0.0 9.1 0.3 0.4 0.7 2.5 0.3 0.3 0.0 2.5 0.1 0.2 1.7 13.5 0.7 898.7 0.2 3.6 3.0 0.0 0.0 0.1 0.9 0.7 0.1 1.1 1.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 2.8 1.7 5.8 1.6 5.3 22.9 6.9 26.5 6.8 13.2 10.0 1.7 250.0 151.5 0.3 0.6 0.3 0.3 2.6 0.0 0.0 3.4 3.4 6.8 0.0 20.9 1.8 0.0 13.8 0.3 0.7 5.9 0.1 0.0 1.3 0.7 1.1 1.8 0.0 0.2 0.0 0.7 6.7 0.5 1.3 3.8 0.1 2.9 0.5 1.1 0.0 0.1 5.5 2.0 0.0 0.3 0.4 0.6 0.8 0.0 2.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.4 154.9 27.8 3.6 0.0 0.0 0.6 22.1 1.7 1.3 0.7 2.7 26.4 1.1 0.0 1.6 0.6 SUSD4 FLJ10052 ENSG00000143502 "Sushi domain containing 4" Q5VX71 1 223220819-223364233 "Predicted intracellular proteins, Predicted membrane proteins" "Complement pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 69.0;esophagus: 51.1" "Cell type enhanced" "Detected in many" "Excitatory neurons: 83.7;Inhibitory neurons: 89.7;Oligodendrocyte precursor cells: 101.6;Squamous epithelial cells: 68.3;Theca cells: 65.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory CD4 T-cell: 6.8;naive CD4 T-cell: 10.2" "Lineage enriched" "Detected in single" 40 "T-cells: 10.2" "Cell line enhanced" "Detected in some" "HaCaT: 9.7;RPTEC TERT1: 11.1;SCLC-21H: 36.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058296 Uncertain Approved Vesicles "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA058296: AB_2683672" "unprognostic (2.90e-1)" "unprognostic (2.90e-3)" "unprognostic (1.27e-3)" "prognostic unfavorable (4.28e-4)" "unprognostic (2.12e-1)" "unprognostic (7.01e-2)" "unprognostic (7.53e-3)" "unprognostic (1.82e-3)" "unprognostic (7.94e-2)" "unprognostic (1.57e-1)" "unprognostic (1.27e-3)" "unprognostic (1.36e-1)" "unprognostic (6.51e-6)" "unprognostic (3.64e-2)" "unprognostic (5.11e-2)" "unprognostic (3.03e-1)" "unprognostic (7.11e-2)" 0.4 6.0 28.4 0.8 21.7 0.4 8.7 5.4 63.7 9.5 0.0 1.3 1.0 0.3 25.1 51.1 3.5 0.7 23.0 69.0 26.8 19.5 3.8 2.8 1.6 9.4 10.4 45.3 10.7 14.9 26.0 0.5 15.9 6.0 0.2 12.2 17.0 4.3 3.5 7.8 0.6 0.4 5.0 0.4 11.0 6.6 21.4 3.4 1.0 2.2 15.0 3.6 25.3 16.2 5.9 0.5 0.2 0.0 0.0 0.0 0.1 0.8 0.4 1.0 0.5 5.8 1.8 0.0 1.8 0.2 0.0 9.7 0.2 1.5 0.9 0.0 2.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.6 0.2 0.0 6.6 0.5 0.0 0.5 3.9 3.8 0.0 0.2 3.0 1.3 0.0 0.2 0.1 11.1 2.8 36.3 0.4 0.0 3.2 0.0 0.8 2.1 0.2 0.0 1.7 6.2 0.0 2.9 0.7 0.1 0.0 0.1 0.1 0.8 0.0 0.1 0.0 0.3 0.1 5.5 0.0 6.8 1.7 0.0 0.0 10.2 1.9 0.0 0.2 0.0 0.0 0.9 1.4 28.4 21.7 5.4 63.7 69.0 26.8 9.4 10.4 15.9 5.0 21.4 16.2 0.2 0.0 4.8 6.2 0.0 0.6 8.6 8.4 10.2 17.9 9.7 5.0 9.5 5.7 14.8 16.5 10.4 0.1 0.3 0.1 31.3 0.6 3.1 4.0 0.4 0.6 1.2 0.0 83.7 6.9 0.0 3.8 2.6 6.1 0.0 9.1 0.4 1.8 2.8 21.9 89.7 0.1 2.0 0.6 0.3 3.4 20.5 0.3 5.4 8.4 0.0 1.6 0.0 101.6 2.5 2.6 0.0 12.4 0.1 4.6 0.0 0.3 5.4 6.2 0.0 1.4 2.8 1.3 10.7 68.3 1.7 0.0 1.7 65.5 0.3 25.7 TAF4B "TAF2C2, TAFII105" ENSG00000141384 "TATA-box binding protein associated factor 4b" Q92750 18 26226445-26391685 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Oogenesis, Spermatogenesis, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 80.3;Plasma cells: 52.3;Suprabasal keratinocytes: 78.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 65.0;U-266/70: 26.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028937 Uncertain Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 30: Non-specific - Translation" "Cluster 2: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 59: Non-specific - Transcription" Nucleoplasm "Nucleoli fibrillar center" "HPA028937: AB_10603034" "unprognostic (2.46e-2)" "unprognostic (1.03e-1)" "unprognostic (1.38e-1)" "unprognostic (1.19e-3)" "unprognostic (1.74e-1)" "unprognostic (2.13e-1)" "unprognostic (5.01e-2)" "unprognostic (2.67e-1)" "unprognostic (3.29e-2)" "unprognostic (2.21e-1)" "unprognostic (4.66e-3)" "unprognostic (3.14e-2)" "prognostic unfavorable (3.08e-4)" "unprognostic (7.38e-2)" "unprognostic (9.56e-2)" "unprognostic (1.58e-1)" "prognostic unfavorable (1.72e-4)" 1.5 2.0 0.4 2.8 0.4 2.8 2.7 0.3 1.9 1.2 0.0 1.6 0.4 1.4 0.3 1.0 1.3 0.7 0.4 0.3 0.2 1.5 0.1 1.0 3.1 0.9 0.1 3.1 1.2 0.6 0.2 1.7 1.1 0.8 1.4 0.3 1.1 0.8 1.3 1.5 0.8 1.2 0.0 2.5 1.8 4.6 0.2 1.8 1.7 0.7 3.2 1.5 0.6 0.8 4.3 0.7 0.3 1.1 1.6 2.6 2.1 1.3 1.5 0.7 1.3 1.1 2.3 65.0 5.0 0.3 2.5 4.8 3.7 4.0 3.4 15.5 9.9 7.5 1.9 1.0 2.3 20.5 4.4 4.3 1.5 0.5 11.6 0.6 1.4 8.1 10.2 7.9 0.3 4.2 10.7 4.1 3.5 2.5 5.1 0.0 8.1 17.3 1.0 0.3 6.1 2.8 3.9 5.7 2.7 1.6 2.0 3.6 0.9 2.7 1.6 3.7 4.8 26.2 18.0 21.8 1.3 12.8 2.4 0.0 0.3 0.0 0.1 0.5 1.0 2.3 0.7 1.0 1.0 2.0 2.0 1.6 0.0 0.6 0.2 0.3 0.1 0.6 0.4 0.4 0.3 1.9 0.3 0.2 0.9 0.1 1.1 0.0 0.2 0.8 7.2 6.4 7.2 6.2 34.0 80.3 9.5 1.7 49.5 1.5 15.0 17.9 2.8 0.0 2.5 0.0 0.0 18.6 4.1 5.8 17.6 1.2 0.7 28.9 9.7 9.0 0.0 21.7 44.8 2.0 4.3 15.5 36.7 45.0 1.3 5.4 1.1 0.0 2.4 5.0 28.3 7.0 2.0 1.6 17.9 1.6 3.4 5.9 23.2 4.7 2.6 0.2 1.0 7.5 11.7 2.2 2.5 4.1 52.3 13.9 0.8 4.0 1.0 1.2 0.0 17.6 12.1 25.4 24.8 40.8 78.8 9.7 14.5 14.5 6.2 6.7 TAP1 "ABCB2, D6S114E, PSF1, RING4" ENSG00000168394 "Transporter 1, ATP binding cassette subfamily B member" Q03518 6 32845209-32853816 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Adaptive immunity, Host-virus interaction, Immunity, Peptide transport, Protein transport, Transport" Translocase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 126.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009516, HPA072354" Approved Approved "Endoplasmic reticulum,Centriolar satellite" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 63: NK-cells & T-cells - Immune response" "Endoplasmic reticulum, Centriolar satellite" "CAB009516: AB_2303048, HPA072354: AB_2686513" "unprognostic (3.59e-2)" "unprognostic (1.06e-1)" "prognostic favorable (9.01e-4)" "unprognostic (1.33e-1)" "unprognostic (1.84e-1)" "unprognostic (3.22e-2)" "unprognostic (4.92e-2)" "unprognostic (6.16e-3)" "unprognostic (2.56e-2)" "prognostic favorable (4.07e-4)" "unprognostic (3.02e-3)" "unprognostic (2.37e-1)" "prognostic unfavorable (6.58e-5)" "unprognostic (2.07e-2)" "unprognostic (4.69e-2)" "unprognostic (2.42e-2)" "unprognostic (2.21e-2)" 28.4 24.9 16.1 50.1 16.2 13.7 20.7 15.8 20.3 21.6 16.2 30.3 36.0 20.5 2.5 31.6 17.8 12.7 25.4 14.7 16.2 21.8 19.3 52.7 50.0 24.0 16.1 12.1 14.5 7.0 11.6 12.1 21.2 21.9 12.5 1.7 25.9 7.0 16.3 51.2 42.6 11.5 18.6 73.0 33.4 11.5 19.4 25.5 17.0 7.4 21.3 23.9 24.4 17.4 22.9 13.7 0.1 16.1 8.8 11.4 126.2 8.1 34.3 59.3 86.5 2.0 27.3 41.8 25.0 12.6 48.9 45.8 4.5 20.6 5.3 81.0 6.1 26.5 4.1 10.8 42.3 0.1 17.5 15.0 17.9 17.1 10.4 8.6 15.4 8.4 1.9 55.0 10.6 10.5 17.7 27.4 0.8 3.1 11.1 47.6 5.2 32.8 25.0 10.5 0.2 1.2 6.7 38.0 33.4 1.7 30.9 37.4 9.7 21.5 8.1 53.1 11.4 59.9 82.6 12.6 16.6 16.6 16.4 176.8 99.5 270.1 155.8 101.6 133.8 137.3 125.2 153.7 95.0 107.5 120.9 124.6 295.6 132.9 94.6 94.8 213.8 221.2 16.1 16.2 15.8 20.3 14.7 16.2 24.0 16.1 21.2 18.6 19.4 17.4 72.1 25.6 24.0 9.1 62.1 74.7 47.1 54.5 27.3 4.8 21.5 15.9 7.3 24.3 33.1 5.5 0.0 5.6 108.0 78.8 5.9 81.6 0.5 31.3 39.3 63.6 16.8 12.6 1.1 75.3 95.0 26.9 42.8 77.9 26.6 13.8 27.1 11.1 45.9 15.2 1.9 55.9 57.0 31.9 90.6 0.3 13.1 43.9 23.2 16.9 115.9 25.1 149.3 12.1 3.6 91.3 38.8 10.5 84.8 70.2 84.6 6.9 29.4 2.8 6.6 18.1 27.8 1.0 1.3 20.4 76.4 4.8 92.3 18.2 54.5 52.1 TBC1D31 "Gm85, MGC21654, WDR67" ENSG00000156787 "TBC1 domain family member 31" Q96DN5 8 123041968-123152153 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 20.6" "Cell type enhanced" "Detected in many" "Astrocytes: 19.9;Excitatory neurons: 23.4;Inhibitory neurons: 32.0;NK-cells: 24.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 83.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023710 Approved Approved Centrosome NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 63: NK-cells & T-cells - Immune response" Centrosome "HPA023710: AB_1858819" "unprognostic (1.39e-1)" "unprognostic (5.44e-3)" "unprognostic (7.21e-2)" "unprognostic (3.18e-5)" "unprognostic (2.42e-1)" "unprognostic (8.98e-2)" "unprognostic (2.63e-2)" "prognostic unfavorable (2.91e-4)" "unprognostic (1.53e-2)" "unprognostic (6.59e-2)" "unprognostic (8.88e-2)" "unprognostic (1.13e-1)" "unprognostic (1.18e-4)" "unprognostic (1.78e-3)" "unprognostic (1.57e-1)" "unprognostic (1.76e-2)" "unprognostic (2.33e-1)" 3.9 2.5 5.8 6.0 7.8 7.4 2.0 20.6 6.6 1.7 5.2 4.2 5.4 2.4 1.4 2.5 4.2 2.2 2.7 7.3 4.1 2.8 3.1 2.5 7.2 4.3 5.5 1.7 3.8 2.9 3.5 1.9 5.1 2.3 3.5 4.9 2.4 1.7 4.4 2.9 4.8 2.7 4.4 5.8 3.4 5.1 6.0 14.4 3.1 2.5 6.1 2.2 1.7 7.3 30.6 19.5 15.4 12.9 5.1 5.5 10.9 17.5 6.4 14.0 12.7 17.9 11.4 11.2 21.5 4.7 9.5 21.1 14.3 7.2 19.7 31.3 31.6 28.8 13.5 8.3 7.7 11.9 20.3 4.4 4.2 11.6 11.9 4.1 10.2 31.0 24.0 23.1 10.2 50.5 37.2 8.1 12.8 26.5 29.8 21.2 14.5 16.8 9.4 11.1 16.8 14.7 31.5 83.2 9.7 9.8 15.8 9.2 8.8 12.8 31.9 11.9 22.1 34.5 58.1 15.1 13.2 20.1 19.0 9.1 10.0 10.6 17.4 12.6 26.6 9.2 10.6 14.3 8.8 8.4 10.8 12.3 5.8 20.5 11.2 7.9 11.6 15.6 5.8 7.8 20.6 6.6 7.3 4.1 4.3 5.5 5.1 4.4 6.0 7.3 2.7 0.0 3.4 19.9 3.7 0.5 1.0 2.4 1.2 2.7 1.0 1.3 14.0 0.0 1.4 1.8 6.2 1.6 10.4 2.4 0.0 1.8 4.9 3.4 3.2 2.4 3.0 12.8 23.4 1.1 2.6 2.6 2.6 1.2 7.6 4.2 1.1 1.8 3.9 0.0 32.0 2.0 0.0 6.6 1.9 2.9 1.5 3.8 1.8 14.0 4.6 1.3 24.7 11.1 13.4 1.0 0.6 1.5 5.8 0.7 1.2 2.2 3.7 5.9 0.0 2.4 2.3 10.9 2.7 4.1 1.3 0.1 12.5 2.5 3.5 0.6 TBX21 "T-bet, TBLYM" ENSG00000073861 "T-box transcription factor 21" Q9UL17 17 47733236-47746122 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" Asthma "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 11.1;lung: 3.3;lymphoid tissue: 11.7" "Cell type enhanced" "Detected in some" "dendritic cells: 92.8;NK-cells: 119.4;Plasma cells: 22.8;T-cells: 45.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "gdT-cell: 15.7;NK-cell: 14.3" "Group enriched" "Detected in many" 7 "NK-cells: 14.3;T-cells: 15.7" "Cell line enriched" "Detected in single" 113 "HDLM-2: 16.3" "Region enriched" "Detected in single" 27 "olfactory bulb: 22.1" "Region enriched" "Detected in single" 4 "olfactory bulb: 4.2" "CAB009524, CAB030043" Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB009524: AB_2200557, CAB030043: AB_1595503" "unprognostic (3.31e-3)" "unprognostic (3.17e-3)" "unprognostic (1.17e-2)" "unprognostic (5.35e-6)" "unprognostic (3.93e-1)" "unprognostic (2.56e-4)" "unprognostic (5.86e-4)" "unprognostic (6.90e-2)" "unprognostic (3.63e-3)" "unprognostic (6.26e-4)" "unprognostic (1.43e-1)" "unprognostic (1.93e-2)" "unprognostic (3.04e-4)" "unprognostic (7.92e-2)" "unprognostic (2.67e-1)" "unprognostic (9.19e-3)" "unprognostic (4.43e-3)" 0.9 0.4 0.3 1.9 0.3 11.1 0.4 0.3 0.3 0.4 0.4 0.5 0.9 0.3 0.4 0.3 0.4 0.8 0.3 0.2 0.3 0.5 1.2 3.3 7.5 0.4 0.3 0.2 0.2 0.0 0.2 0.2 0.3 0.4 0.5 0.0 0.6 0.2 0.5 0.2 1.6 0.4 0.3 11.7 1.2 0.4 0.3 1.0 0.7 0.2 2.2 0.6 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.7 0.0 3.6 2.0 3.1 8.9 0.0 0.5 0.4 7.8 0.2 14.3 0.0 0.1 0.1 2.4 0.3 0.3 0.3 0.3 0.2 0.3 0.4 0.3 0.3 0.3 0.3 0.3 1.1 0.0 0.6 0.0 7.6 0.0 0.0 0.0 0.6 0.0 0.6 0.9 1.3 1.5 0.0 0.0 0.0 0.1 92.8 0.0 0.0 0.0 0.0 0.1 0.2 0.5 0.0 1.3 0.1 0.0 0.0 0.2 1.1 0.2 2.5 0.0 0.4 0.4 0.1 0.0 0.0 0.0 0.0 1.4 0.4 0.0 0.0 1.9 0.0 1.9 0.8 0.0 119.4 0.0 0.1 0.0 0.0 0.0 22.8 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.4 0.0 0.8 0.1 0.1 0.0 45.6 0.0 0.0 0.0 TBX3 "TBX3-ISO, UMS, XHL" ENSG00000135111 "T-box transcription factor 3" O15119 12 114670255-114684175 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 178.4" "Cell type enriched" "Detected in many" 4 "Syncytiotrophoblasts: 613.9" "Cancer enhanced" "Detected in all" "prostate cancer: 49.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 103.0;BJ hTERT+: 97.3;RT4: 129.3" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA005799, HPA075876" Supported Nucleoplasm,Cytosol NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm Cytosol "HPA005799: AB_1857817, HPA075876: " "unprognostic (3.27e-1)" "unprognostic (2.64e-1)" "unprognostic (2.84e-1)" "unprognostic (1.11e-1)" "unprognostic (3.40e-2)" "unprognostic (5.97e-3)" "unprognostic (1.56e-1)" "unprognostic (2.99e-2)" "unprognostic (9.43e-2)" "unprognostic (1.15e-1)" "unprognostic (3.35e-1)" "unprognostic (3.06e-1)" "unprognostic (3.64e-3)" "unprognostic (1.09e-3)" "unprognostic (1.43e-1)" "unprognostic (1.01e-1)" "prognostic favorable (3.28e-4)" 13.3 178.4 5.1 2.5 4.7 0.0 34.1 3.9 5.7 37.5 2.9 7.4 37.6 32.8 44.6 2.8 24.0 4.5 13.2 3.8 14.9 12.9 31.3 32.8 1.4 4.6 4.4 44.2 2.9 1.0 12.9 41.3 4.8 80.4 3.7 1.8 18.9 53.2 10.4 14.9 30.3 10.0 3.8 7.0 6.0 1.3 6.6 1.3 50.0 16.5 1.7 53.9 34.2 3.7 2.4 18.2 0.0 0.0 26.1 35.6 40.1 103.0 97.3 39.0 38.3 16.3 4.4 0.0 1.6 18.0 2.4 4.7 8.4 3.6 47.7 0.0 12.3 0.0 4.8 48.1 8.4 0.0 0.0 16.0 2.4 13.1 26.8 0.0 0.5 0.0 3.8 0.0 3.4 1.6 0.0 0.5 0.2 53.0 5.4 0.0 0.0 2.6 0.0 129.3 6.6 19.4 14.6 6.6 3.6 44.6 5.1 0.2 0.0 11.9 7.7 6.8 33.9 0.0 0.0 0.0 24.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 4.7 3.9 5.7 3.8 14.9 4.6 4.4 4.8 3.8 6.6 3.7 48.9 0.0 1.9 0.3 1.8 9.8 85.2 5.8 7.4 14.3 110.3 80.5 12.5 0.0 1.1 35.0 4.2 60.7 0.7 12.0 0.0 0.6 1.5 3.3 144.7 38.6 4.9 0.0 0.0 0.0 7.0 41.3 5.1 3.8 0.0 3.9 1.1 40.2 6.1 1.7 0.0 23.9 4.1 0.9 4.6 2.8 5.3 2.9 3.6 14.0 0.0 1.9 0.0 0.0 0.0 0.3 22.4 6.0 0.0 72.4 37.9 0.1 0.4 2.0 39.5 27.2 58.2 0.1 3.8 3.2 9.8 613.9 2.0 112.0 12.1 69.1 TCEA3 TFIIS.H ENSG00000204219 "Transcription elongation factor A3" O75764 1 23380909-23424748 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 513.3" "Cell type enhanced" "Detected in many" "Granulosa cells: 214.8;Hepatocytes: 205.9;Intestinal goblet cells: 376.2;Proximal tubular cells: 260.9;Undifferentiated cells: 223.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory CD4 T-cell: 8.4;naive CD4 T-cell: 13.6" "Lineage enriched" "Detected in many" 5 "T-cells: 13.6" "Cell line enhanced" "Detected in many" "ASC TERT1: 15.3;Hep G2: 55.1;OE19: 28.7;SiHa: 18.2;T-47d: 28.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA044960, HPA055811" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 32: T-cells - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Vesicles "HPA044960: AB_10964053, HPA055811: AB_2682932" "unprognostic (1.58e-1)" "unprognostic (1.75e-3)" "unprognostic (9.18e-2)" "unprognostic (3.82e-2)" "unprognostic (2.77e-3)" "prognostic favorable (2.56e-4)" "unprognostic (2.86e-2)" "unprognostic (4.70e-3)" "unprognostic (7.37e-3)" "unprognostic (2.85e-1)" "unprognostic (2.22e-2)" "unprognostic (3.27e-1)" "unprognostic (2.23e-1)" "unprognostic (4.01e-1)" "unprognostic (5.20e-2)" "unprognostic (3.15e-1)" "unprognostic (5.58e-2)" 17.5 95.6 4.7 4.6 4.3 0.6 19.6 4.1 4.7 35.7 7.8 87.1 15.8 17.0 7.3 40.5 28.3 11.6 71.6 4.0 4.4 64.9 160.7 20.4 2.4 6.0 4.9 81.9 229.4 16.3 14.9 3.9 5.4 59.9 39.8 3.2 100.3 14.5 513.3 53.4 35.2 9.2 5.2 10.6 75.9 4.7 4.1 1.8 41.2 173.1 4.5 36.2 38.7 5.1 0.0 0.1 0.5 0.5 2.5 15.3 9.0 6.4 4.1 3.2 1.9 4.1 0.5 0.2 0.7 7.9 1.0 9.1 0.5 0.1 2.8 0.0 0.1 0.0 6.9 55.1 1.9 0.8 0.0 10.1 2.8 2.9 0.0 7.1 0.4 0.1 0.0 0.0 1.1 1.5 0.4 6.1 0.0 28.7 1.8 0.1 0.0 0.2 0.0 0.1 0.5 0.1 18.2 0.8 0.8 1.5 28.4 2.8 0.4 0.0 0.2 0.7 0.0 0.5 5.3 0.0 0.5 0.5 0.6 0.0 0.2 0.0 0.4 0.7 0.4 0.0 8.4 1.1 2.9 0.0 13.6 6.1 0.0 0.2 0.2 0.9 0.8 2.3 4.7 4.3 4.1 4.7 4.0 4.4 6.0 4.9 5.4 5.2 4.1 5.1 10.5 125.0 109.5 4.2 1.9 27.4 53.4 30.9 30.7 2.3 46.3 42.4 109.8 100.1 57.2 42.3 2.1 3.3 1.9 158.0 199.6 37.7 6.1 7.7 6.6 13.4 55.9 5.7 2.8 97.9 33.9 45.2 69.3 20.8 9.5 214.8 8.2 205.9 1.5 25.2 4.5 376.2 6.1 7.6 65.4 17.9 17.1 8.4 24.9 3.7 3.2 6.8 3.1 2.0 1.3 25.5 143.0 15.4 0.5 38.8 154.3 260.9 29.4 1.4 19.7 90.1 24.0 0.7 2.6 61.1 54.8 2.2 8.4 52.0 223.5 73.9 TCF19 SC1 ENSG00000137310 "Transcription factor 19" Q9Y242 6 31158547-31167159 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Erythroid cells: 37.0;Glandular and luminal cells: 17.6;Plasma cells: 21.1" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "A-431: 82.8;GAMG: 47.0;HEK 293: 43.3;JURKAT: 40.9;Karpas-707: 39.2;SCLC-21H: 48.5;U-138 MG: 49.0" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA065994 Approved Nucleoplasm,Nucleoli NA Yes "Cluster 35: T-regs - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Nucleoli "HPA065994: " "unprognostic (1.41e-2)" "unprognostic (4.92e-2)" "unprognostic (4.00e-2)" "unprognostic (5.16e-3)" "unprognostic (1.99e-2)" "unprognostic (6.04e-2)" "prognostic unfavorable (5.66e-4)" "unprognostic (7.04e-2)" "unprognostic (1.35e-2)" "unprognostic (5.92e-2)" "unprognostic (1.74e-3)" "unprognostic (1.56e-2)" "prognostic unfavorable (3.54e-10)" "unprognostic (3.11e-2)" "unprognostic (1.05e-1)" "unprognostic (1.36e-2)" "unprognostic (1.21e-1)" 4.6 1.7 0.3 2.6 0.4 1.0 4.3 0.7 0.4 6.9 0.2 5.8 4.4 4.2 2.1 12.5 3.8 0.4 3.7 0.3 0.3 4.1 2.0 4.4 10.0 0.5 0.4 4.8 3.2 0.0 1.3 0.3 0.5 5.1 1.7 0.6 4.7 0.8 2.7 8.9 7.2 1.1 0.3 9.5 5.5 1.9 0.7 0.0 2.4 0.1 1.7 5.2 8.1 0.3 82.8 0.7 0.7 0.1 5.4 7.0 0.7 0.5 0.0 0.1 0.1 5.3 0.1 0.1 17.7 20.1 47.0 0.1 0.0 30.3 0.0 0.5 43.3 7.3 5.1 2.0 0.0 0.2 21.1 2.9 0.0 2.3 0.0 4.4 17.9 40.9 0.1 39.2 8.1 0.3 1.2 13.2 0.1 0.0 0.0 1.1 4.8 0.7 7.1 0.3 48.5 0.5 0.4 0.1 0.5 6.5 0.1 6.0 0.0 49.0 0.2 0.4 0.4 12.5 15.0 24.8 0.1 0.3 0.3 0.0 0.1 0.0 0.2 0.0 1.3 0.5 0.6 1.1 0.3 0.5 0.8 0.2 0.1 0.4 0.0 0.0 1.0 0.5 0.3 0.4 0.7 0.4 0.3 0.3 0.5 0.4 0.5 0.3 0.7 0.3 2.8 3.2 0.6 0.7 6.7 5.1 3.1 2.5 8.6 3.0 2.8 2.9 1.2 0.0 2.5 3.7 0.0 2.9 3.9 1.8 7.9 1.3 0.3 4.7 2.0 4.7 1.2 37.0 0.1 1.8 9.6 5.6 5.6 17.6 1.3 7.0 1.8 0.6 8.9 1.7 0.2 3.9 2.0 2.9 5.4 0.7 5.0 4.8 12.4 0.0 6.0 4.2 8.2 0.0 0.2 1.1 0.9 6.4 21.1 1.3 1.6 0.4 0.2 0.5 0.0 3.5 5.3 0.7 11.1 9.6 3.8 0.4 7.6 2.0 8.8 2.9 TCHP "MGC10854, TpMs" ENSG00000139437 "Trichoplein keratin filament binding" Q9BT92 12 109900264-109983841 "Predicted intracellular proteins" "Apoptosis, Cilium biogenesis/degradation" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA038638, HPA061543" Supported Approved "Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 32: U-937 - Innate immune response" "Cluster 52: Non-specific - Transcription" "Plasma membrane, Centrosome, Cytosol" "HPA038638: AB_10670785, HPA061543: AB_2684556" "unprognostic (2.21e-1)" "unprognostic (1.51e-2)" "unprognostic (2.58e-1)" "unprognostic (1.04e-1)" "unprognostic (2.58e-1)" "unprognostic (4.82e-2)" "unprognostic (1.42e-2)" "unprognostic (7.94e-2)" "unprognostic (1.59e-2)" "unprognostic (9.75e-2)" "unprognostic (1.15e-3)" "unprognostic (4.63e-2)" "unprognostic (1.22e-1)" "prognostic favorable (5.52e-4)" "unprognostic (1.35e-1)" "unprognostic (1.32e-1)" "unprognostic (4.92e-2)" 6.5 7.3 9.7 8.9 10.6 6.8 6.6 10.9 11.3 10.1 8.1 10.4 7.3 9.1 7.5 15.4 7.6 5.9 8.1 9.4 10.5 7.8 5.6 7.3 11.7 10.4 10.5 8.9 10.9 7.4 6.4 7.6 10.5 8.6 6.8 9.2 10.5 7.9 9.1 27.4 8.2 7.6 9.2 11.8 8.2 9.3 10.7 10.4 8.6 7.0 11.6 9.3 13.8 11.0 27.6 24.0 12.7 15.3 11.0 11.9 17.3 25.6 13.4 21.8 12.1 15.2 9.4 38.2 7.2 14.9 11.8 22.5 14.0 16.0 19.5 20.7 13.8 27.6 15.3 15.0 13.3 38.0 20.4 9.8 19.1 22.9 17.1 13.7 19.7 23.8 30.5 7.5 18.2 18.9 35.0 38.4 15.3 6.6 24.2 31.7 24.9 32.4 9.9 24.2 18.8 19.8 18.5 19.8 18.2 9.0 17.9 27.2 21.8 22.2 15.5 14.3 32.7 21.8 29.5 27.0 23.5 31.0 23.7 0.0 2.7 2.3 3.6 1.7 2.6 2.0 3.2 4.5 2.1 1.3 3.2 2.5 2.7 5.9 3.7 1.5 4.7 3.1 9.7 10.6 10.9 11.3 9.4 10.5 10.4 10.5 10.5 9.2 10.7 11.0 11.7 19.2 21.4 18.9 10.4 9.8 7.7 9.5 8.0 28.9 11.3 11.4 13.2 17.2 12.0 7.3 18.8 11.2 14.3 12.8 9.8 20.7 32.5 23.0 19.1 15.2 14.8 15.4 8.3 15.1 8.4 11.4 10.2 13.2 13.3 15.7 7.9 7.4 11.6 25.2 12.3 10.7 10.2 13.0 7.8 47.6 11.1 11.4 7.2 1.9 14.3 13.9 35.0 10.1 19.4 18.8 14.4 27.8 15.0 9.1 14.2 6.6 33.6 24.0 13.1 19.6 12.6 25.1 33.2 14.8 24.7 7.0 15.9 30.9 12.2 30.7 TEAD4 "EFTR-2, RTEF-1, TCF13L1, TEF-3, TEFR-1" ENSG00000197905 "TEA domain transcription factor 4" Q15561 12 2959330-3040676 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 127.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 50.3;Exocrine glandular cells: 38.3;Hepatic stellate cells: 32.2;Proximal enterocytes: 37.9;Syncytiotrophoblasts: 34.6" "Cancer enriched" "Detected in all" 5 "testis cancer: 78.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 364.1" "Region enriched" "Detected in single" 5 "cerebellum: 3.1" "Low region specificity" "Detected in all" HPA056896 Uncertain Supported Nucleoplasm NA NA "Cluster 59: Non-specific - Translation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "HPA056896: AB_2683268" "unprognostic (3.68e-1)" "unprognostic (3.98e-1)" "unprognostic (2.17e-1)" "unprognostic (1.55e-3)" "unprognostic (1.33e-1)" "unprognostic (3.68e-1)" "unprognostic (9.20e-3)" "unprognostic (2.21e-3)" "unprognostic (3.01e-1)" "unprognostic (1.24e-1)" "unprognostic (2.50e-2)" "unprognostic (2.03e-1)" "prognostic unfavorable (9.78e-9)" "unprognostic (5.05e-3)" "unprognostic (8.43e-2)" "unprognostic (2.42e-2)" "unprognostic (1.23e-3)" 17.4 5.2 4.2 7.1 3.6 0.4 12.0 5.6 5.5 10.4 4.0 8.1 4.8 9.7 1.0 7.8 8.3 4.5 20.0 3.5 3.9 33.7 4.6 26.0 1.6 5.3 4.8 4.5 51.1 1.6 3.4 10.9 6.1 8.5 4.1 0.5 8.0 5.0 127.3 16.4 8.4 8.9 4.0 9.0 8.1 3.7 6.4 1.6 23.6 46.7 2.4 11.3 7.1 3.6 37.6 51.5 13.0 36.2 4.0 8.7 137.8 29.5 15.6 49.7 27.8 99.6 39.0 0.3 22.2 22.5 34.0 52.5 51.2 364.1 46.1 0.2 41.2 59.1 43.7 87.7 18.8 12.8 10.7 12.2 14.8 43.3 66.7 20.8 42.9 23.4 38.4 0.5 17.5 53.2 0.7 0.3 99.5 48.0 30.0 27.4 73.7 28.9 23.6 15.3 7.4 13.2 36.4 89.9 27.1 93.8 61.2 21.8 49.4 28.7 100.1 20.2 15.7 0.1 0.2 0.4 23.3 0.0 37.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 3.6 5.6 5.5 3.5 3.9 5.3 4.8 6.1 4.0 6.4 3.6 17.1 12.8 4.7 0.0 0.1 12.2 12.6 6.1 9.1 0.1 6.6 3.7 2.4 5.7 2.3 7.3 0.0 50.3 0.4 3.7 5.9 17.7 0.3 3.0 5.1 25.9 0.0 0.0 1.6 38.3 18.3 6.6 4.1 5.0 5.7 3.4 32.2 0.4 5.2 0.0 0.5 3.7 2.0 0.8 1.5 2.3 0.0 0.5 8.8 3.7 0.0 0.0 0.0 0.0 0.4 21.1 0.9 0.4 1.2 28.9 37.9 21.1 1.5 0.1 0.0 9.3 12.2 0.5 6.4 5.4 7.7 34.6 0.5 0.4 7.1 4.9 TERB2 "C15orf43, MGC33951" ENSG00000167014 "Telomere repeat binding bouquet formation protein 2" Q8NHR7 15 44956687-44979229 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "testis: 22.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA041780 Uncertain Nucleoplasm,Nucleoli No NA "Cluster 83: Testis - Spermatogenesis" Nucleoli Nucleoplasm "HPA041780: AB_10796460" "unprognostic (1.42e-3)" "unprognostic (4.19e-2)" "unprognostic (1.29e-1)" "unprognostic (3.62e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TESK2 ENSG00000070759 "Testis associated actin remodelling kinase 2" Q96S53 1 45343883-45491163 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 222.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 14.6;RT4: 14.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027257, HPA063869" Uncertain Enhanced Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA027257: AB_10602477, HPA063869: AB_2685137" "unprognostic (2.95e-1)" "prognostic favorable (2.22e-4)" "unprognostic (3.90e-2)" "unprognostic (5.04e-3)" "unprognostic (6.03e-2)" "unprognostic (1.87e-3)" "unprognostic (3.22e-2)" "unprognostic (1.43e-2)" "unprognostic (5.15e-2)" "unprognostic (2.96e-1)" "unprognostic (2.28e-1)" "unprognostic (2.86e-1)" "unprognostic (4.36e-2)" "unprognostic (2.49e-2)" "unprognostic (1.13e-1)" "unprognostic (4.37e-2)" "unprognostic (2.01e-1)" 3.8 2.1 7.1 2.8 10.6 10.2 6.6 10.3 8.3 6.4 4.8 5.3 8.6 3.2 3.7 7.1 3.0 2.6 2.4 7.3 8.0 2.5 6.9 3.9 3.9 10.8 10.1 9.8 3.6 3.4 2.4 3.5 10.3 15.5 7.0 2.8 8.4 2.6 8.3 12.7 10.8 2.9 8.5 5.3 4.5 9.6 9.9 4.2 3.4 4.7 5.2 4.7 7.4 15.1 1.9 0.0 0.9 0.1 3.5 1.8 14.6 0.7 4.9 2.1 3.6 4.3 1.7 6.2 0.6 1.8 5.4 2.3 3.9 3.1 1.6 4.4 4.9 4.2 2.0 3.2 1.9 1.4 11.1 1.9 3.2 2.4 3.4 3.2 1.7 8.1 0.8 12.4 1.4 0.7 3.6 2.9 3.8 1.8 1.8 5.2 0.1 1.5 1.9 14.7 0.4 1.6 3.8 7.3 14.1 8.6 11.3 1.8 0.0 0.2 2.1 1.3 1.3 8.0 5.0 1.2 1.1 0.0 1.0 12.8 4.6 13.3 2.7 3.4 1.9 8.0 2.5 1.8 2.4 6.6 4.1 2.3 19.0 1.5 8.0 1.3 1.9 3.4 7.1 10.6 10.3 8.3 7.3 8.0 10.8 10.1 10.3 8.5 9.9 15.1 3.9 0.0 2.8 54.2 10.7 7.8 7.1 2.8 14.2 2.4 11.9 9.4 1.3 4.3 3.4 0.0 14.6 8.3 4.2 13.9 0.0 1.3 23.7 4.6 1.8 3.2 4.2 5.0 10.2 2.7 2.8 3.7 7.7 8.9 7.0 2.4 2.2 6.3 6.8 0.0 6.7 6.9 4.1 5.5 4.4 7.8 2.8 6.0 3.6 15.9 4.6 1.1 4.1 18.6 222.9 1.1 7.3 1.9 9.8 10.6 14.9 1.2 2.0 3.1 6.6 2.6 6.1 22.0 13.6 12.6 8.5 14.8 4.7 1.8 4.9 8.0 TF "PRO1557, PRO2086" ENSG00000091513 Transferrin P02787 3 133746040-133796641 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Ion transport, Iron transport, Transport" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "liver: 7525.8;retina: 2433.0" "Group enriched" "Detected in many" 9 "Hepatocytes: 7205.2;Muller glia cells: 12965.3" "Cancer enriched" "Detected in many" 42 "liver cancer: 783.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 48 "Hep G2: 780.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001527, HPA005692, CAB009538" Enhanced "Secreted to blood" NA NA 19800000000000 98000000000 "Cluster 17: Basophils - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 5: Muller glia cells - Visual perception" "CAB009538: AB_793365, HPA001527: AB_1080357, HPA005692: AB_1080354" "prognostic favorable (4.05e-4)" "unprognostic (2.45e-2)" "unprognostic (1.78e-1)" "unprognostic (1.50e-1)" "unprognostic (8.99e-2)" "unprognostic (5.18e-2)" "unprognostic (6.63e-2)" "unprognostic (8.46e-2)" "unprognostic (2.82e-1)" "unprognostic (3.08e-1)" "unprognostic (1.37e-1)" "unprognostic (7.60e-2)" "prognostic unfavorable (2.35e-13)" "unprognostic (2.17e-3)" "unprognostic (5.49e-2)" "unprognostic (3.47e-3)" "unprognostic (9.70e-2)" 80.9 1.2 186.3 1.0 412.5 2.4 13.3 591.8 274.2 2.0 58.9 2.3 0.9 1.7 1.4 11.0 1.4 1.9 12.1 173.7 287.7 3.4 7525.8 1.9 1.3 786.9 385.4 2.1 4.6 2.2 4.4 1.3 628.2 5.4 1.2 2433.0 55.8 1.8 2.1 4.2 1.6 1.5 484.9 2.9 1.9 14.3 398.1 1.2 2.2 2.7 3.0 1.2 2.8 862.1 1.9 1.4 1.8 1.2 5.5 3.4 0.9 1.9 2.0 1.0 0.8 3.4 1.5 1.7 1.6 1.8 1.2 2.1 1.3 1.8 1.5 1.1 0.7 16.3 2.7 780.9 1.3 4.6 2.7 2.4 3.8 1.0 1.7 1.8 2.2 0.9 6.4 2.1 2.6 1.3 1.1 1.2 1.2 1.2 1.8 1.5 2.9 1.2 1.1 3.1 1.9 1.4 2.4 2.6 7.0 1.3 1.9 1.3 2.9 2.4 1.5 1.6 1.1 1.7 3.0 1.4 2.0 1.5 1.6 0.6 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.4 0.1 0.1 0.1 0.0 0.0 186.3 412.5 591.8 274.2 173.7 287.7 786.9 385.4 628.2 484.9 398.1 862.1 0.7 16.0 32.4 36.2 11.4 1.0 5.6 0.6 0.0 101.3 5.3 4.3 2.7 117.2 22.9 0.0 91.8 0.2 0.2 0.1 1.9 0.7 5.4 0.8 1.0 16.7 0.0 56.2 34.2 1.1 0.3 3.9 0.0 0.6 17.7 1.3 87.4 7205.2 0.1 47.1 34.7 0.0 0.0 124.7 0.3 3.8 0.3 4.7 0.0 9.4 0.6 12965.3 0.0 45.2 1077.2 1.1 0.0 0.4 0.0 18.7 0.0 0.5 22.1 400.4 0.0 11.6 0.4 0.5 0.4 3.6 0.0 0.3 7.8 0.5 0.0 3.0 TFAP2A "AP-2, AP2TF, TFAP2" ENSG00000137203 "Transcription factor AP-2 alpha" P05549 6 10393186-10419659 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 32.8;skin 1: 66.7" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 167.9;Cytotrophoblasts: 285.8;Extravillous trophoblasts: 260.6;Squamous epithelial cells: 147.7;Syncytiotrophoblasts: 700.1" "Cancer enhanced" "Detected in many" "melanoma: 45.6" "Group enriched" "Detected in many" 4 "cerebellum: 4.1;medulla oblongata: 3.0;midbrain: 1.3;pons: 2.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HDLM-2: 104.7;hTCEpi: 97.3;SuSa: 97.3" "Group enriched" "Detected in some" 4 "cerebellum: 3.9;pons and medulla: 1.0" "Low region specificity" "Detected in many" "CAB000326, HPA056871" Enhanced Enhanced Nucleoplasm NA NA "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm "CAB000326: AB_667767, HPA056871: AB_2683262" "unprognostic (5.97e-2)" "unprognostic (2.18e-1)" "unprognostic (1.31e-2)" "unprognostic (1.14e-1)" "unprognostic (3.87e-2)" "unprognostic (1.27e-1)" "unprognostic (7.62e-5)" "prognostic unfavorable (1.09e-4)" "unprognostic (1.45e-1)" "unprognostic (2.76e-2)" "unprognostic (3.33e-3)" "unprognostic (2.82e-1)" "unprognostic (1.40e-11)" "unprognostic (1.46e-2)" "unprognostic (2.14e-1)" "unprognostic (1.72e-4)" "unprognostic (2.25e-2)" 0.5 0.4 0.4 0.1 0.3 0.1 32.8 4.1 0.4 7.5 0.2 1.1 0.5 0.3 21.8 29.9 0.4 0.2 0.9 0.3 0.1 7.4 0.1 0.5 0.4 3.0 1.3 0.4 0.2 0.6 0.4 29.6 2.1 9.8 0.5 8.1 23.5 9.3 0.5 66.7 0.8 0.1 0.5 0.1 1.4 2.2 0.5 0.2 0.5 0.1 5.1 3.5 16.6 0.6 51.8 17.8 0.1 87.9 0.4 0.0 19.7 40.2 30.3 31.7 31.4 2.1 19.3 3.2 4.9 12.0 17.5 53.2 4.3 66.1 30.9 104.7 45.2 0.4 44.5 0.0 0.0 1.7 1.5 0.0 97.3 0.1 66.6 18.3 0.0 0.9 3.3 0.1 0.3 12.2 0.0 17.2 0.5 3.3 24.7 5.9 5.0 2.2 18.8 21.8 12.5 0.3 44.1 82.7 82.3 97.3 56.0 1.7 0.0 9.9 2.7 7.1 25.3 0.1 5.1 0.8 5.1 1.7 59.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 4.1 0.4 0.3 0.1 3.0 1.3 2.1 0.5 0.5 0.6 0.5 0.0 0.0 0.0 0.4 130.6 45.5 50.3 167.9 25.9 98.2 65.7 2.7 0.0 30.5 31.3 2.1 285.8 0.5 1.0 7.9 2.2 5.3 1.2 0.7 2.1 1.2 0.0 0.0 0.4 260.6 4.2 0.0 1.5 0.0 0.1 0.0 0.0 20.4 80.8 0.0 0.5 46.8 0.0 6.1 3.8 0.6 0.5 124.5 0.0 0.0 4.3 0.0 0.0 0.1 3.7 0.5 0.0 1.2 58.2 0.1 0.3 21.5 4.6 0.0 0.3 4.1 6.5 16.8 147.7 138.4 700.1 0.3 0.3 0.5 46.7 TFAP2C "AP2-GAMMA, ERF1, hAP-2g, TFAP2G" ENSG00000087510 "Transcription factor AP-2 gamma" Q92754 20 56629306-56639283 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 29.1;skin 1: 53.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 132.4;Basal squamous epithelial cells: 120.1;Breast glandular cells: 66.1;Breast myoepithelial cells: 79.6;Cytotrophoblasts: 91.7;Extravillous trophoblasts: 59.7;Squamous epithelial cells: 81.0;Suprabasal keratinocytes: 149.3;Syncytiotrophoblasts: 105.6" "Cancer enhanced" "Detected in many" "testis cancer: 54.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "BEWO: 190.6;MCF7: 169.2;SK-BR-3: 308.9;T-47d: 86.8;WM-115: 114.7" "Region enriched" "Detected in single" 13 "olfactory bulb: 2.4" "Region enhanced" "Detected in single" "olfactory bulb: 1.4" "CAB016061, CAB016079, HPA055179, HPA057076" Enhanced Supported Nucleoplasm Yes NA "Cluster 31: Skin - Epidermis development" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "CAB016061: AB_667770, CAB016079: AB_2199447, HPA055179: AB_2682729, HPA057076: AB_2683329" "unprognostic (1.74e-2)" "prognostic favorable (6.90e-4)" "unprognostic (2.24e-2)" "unprognostic (2.02e-2)" "unprognostic (1.52e-2)" "unprognostic (6.75e-2)" "unprognostic (2.54e-2)" "unprognostic (8.26e-2)" "unprognostic (2.97e-1)" "unprognostic (1.61e-1)" "unprognostic (3.14e-3)" "unprognostic (2.63e-1)" "unprognostic (9.04e-5)" "unprognostic (2.31e-1)" "unprognostic (1.85e-1)" "unprognostic (6.71e-2)" "unprognostic (3.28e-2)" 1.8 0.3 1.3 0.2 0.6 0.1 26.1 0.5 1.5 18.3 0.5 4.0 0.2 6.2 5.2 29.1 2.6 1.0 0.3 1.7 0.7 2.0 0.0 2.6 0.1 0.9 0.8 0.3 1.0 2.6 0.8 17.0 1.2 7.1 1.2 2.7 20.7 4.4 2.1 53.3 0.3 1.1 0.5 0.1 0.7 1.0 0.6 0.7 2.3 0.1 3.0 3.9 19.2 1.0 12.8 15.8 0.1 0.2 0.0 0.0 190.6 20.1 36.4 25.0 4.5 3.2 0.3 0.0 1.3 13.3 13.3 42.7 27.3 5.5 17.0 0.1 2.8 0.0 1.7 0.0 0.0 0.0 1.7 0.3 21.4 7.4 7.2 0.0 0.0 8.1 0.2 3.2 0.0 169.2 20.8 1.2 9.5 9.9 20.7 0.1 0.0 7.0 0.0 10.1 5.1 0.1 13.6 308.9 21.8 28.3 86.8 4.6 0.2 16.2 0.4 8.6 15.4 0.1 0.0 0.1 4.0 0.1 114.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.6 0.5 1.5 1.7 0.7 0.9 0.8 1.2 0.5 0.6 1.0 0.7 0.0 9.5 3.9 0.3 132.4 29.9 2.4 120.1 4.1 66.1 79.6 1.0 0.0 5.6 9.2 0.0 91.7 1.5 1.7 0.0 0.3 0.3 7.8 18.7 2.0 3.0 0.0 0.0 0.0 59.7 7.4 1.5 16.0 0.0 0.0 0.7 0.0 7.8 0.0 0.0 1.7 10.2 0.3 8.2 0.0 0.0 1.6 21.4 3.7 0.0 0.3 0.0 0.0 0.0 1.0 0.6 0.0 3.8 18.6 0.0 0.0 5.2 0.0 0.0 0.5 2.1 0.0 1.8 81.0 149.3 105.6 1.3 0.0 1.0 18.5 TFAP4 "AP-4, bHLHc41" ENSG00000090447 "Transcription factor AP-4" Q01664 16 4257186-4273075 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 30.1;Proximal enterocytes: 40.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001912 Supported Supported Nucleoplasm,Mitochondria NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 50: Non-specific - Ribosome" "Cluster 24: NB-4 - Immune response" "Cluster 32: Non-specific - Translation" "Nucleoplasm, Mitochondria" "HPA001912: AB_1080251" "unprognostic (1.61e-2)" "unprognostic (1.36e-1)" "unprognostic (5.10e-2)" "unprognostic (4.42e-3)" "unprognostic (8.61e-2)" "unprognostic (1.15e-2)" "prognostic unfavorable (3.32e-4)" "unprognostic (8.05e-2)" "unprognostic (8.97e-2)" "unprognostic (4.60e-1)" "unprognostic (5.75e-2)" "unprognostic (7.68e-2)" "prognostic unfavorable (4.31e-6)" "unprognostic (1.08e-2)" "unprognostic (3.25e-1)" "unprognostic (2.39e-2)" "unprognostic (1.30e-1)" 6.2 4.2 3.7 6.9 3.8 1.9 5.8 5.3 5.4 9.0 1.7 5.4 6.4 7.8 1.0 8.1 6.9 3.8 3.2 3.5 3.2 3.6 5.3 3.9 6.8 3.9 3.7 10.0 12.0 3.3 4.3 3.7 3.9 5.7 1.9 0.7 7.6 3.1 7.5 10.5 6.8 2.5 3.5 7.3 5.0 1.7 3.7 8.3 4.6 3.1 3.9 6.4 8.4 5.1 14.9 15.4 12.9 19.2 5.4 14.1 21.7 5.7 14.6 9.6 10.5 8.1 23.0 51.0 14.5 5.5 4.5 22.0 23.6 19.4 3.0 29.8 17.4 15.6 13.0 21.1 7.5 27.8 8.8 13.3 12.2 10.4 29.0 4.5 6.4 16.7 29.1 13.1 3.8 23.9 39.2 46.4 29.8 14.7 20.2 34.3 28.8 53.7 3.7 11.2 27.0 20.0 19.2 19.7 18.9 2.0 10.0 21.9 4.2 13.1 10.4 46.2 15.1 21.3 19.3 43.6 8.8 27.2 9.5 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 3.7 3.8 5.3 5.4 3.5 3.2 3.9 3.7 3.9 3.5 3.7 5.1 7.0 3.2 0.0 2.3 11.6 21.5 9.8 5.7 30.1 4.2 8.1 6.6 2.2 7.2 2.1 27.6 0.0 7.7 5.3 5.3 7.9 4.1 0.1 2.4 9.6 5.4 7.8 22.7 3.0 5.7 11.7 7.6 10.7 3.1 0.0 6.9 3.6 3.4 4.2 0.0 3.9 12.4 8.2 4.0 7.4 0.1 11.8 3.7 3.6 1.0 4.7 2.2 5.2 1.5 3.6 2.9 5.3 5.3 7.2 11.1 40.0 5.7 1.4 3.4 6.6 6.9 7.1 0.9 0.9 22.1 22.3 2.2 7.3 7.5 20.2 4.3 TGM7 TGMZ ENSG00000159495 "Transglutaminase 7" Q96PF1 15 43276271-43302255 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 1.6" "Group enriched" "Detected in some" 11 "Early spermatids: 62.0;Late spermatids: 16.7" "Cancer enriched" "Detected in single" 13 "endometrial cancer: 2.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 35 "EFO-21: 3.5" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 16: Immune cells - Immune response" "Cluster 38: EFO-21 - Unknown function" "Cluster 29: Early spermatids - Spermatogenesis" "unprognostic (2.45e-2)" "unprognostic (2.04e-1)" "unprognostic (2.82e-2)" "unprognostic (1.71e-2)" "unprognostic (1.07e-1)" "unprognostic (2.01e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.4 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 62.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 16.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.8 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 3.5 THEM5 FLJ37964 ENSG00000196407 "Thioesterase superfamily member 5" Q8N1Q8 1 151847101-151853712 "Enzymes, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 24 "skin 1: 158.5" "Cell type enriched" "Detected in some" 18 "Suprabasal keratinocytes: 34.7" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 4 "amygdala: 2.1;cerebral cortex: 4.0;hippocampal formation: 3.0;white matter: 1.0" "Immune cell enhanced" "Detected in single" "MAIT T-cell: 1.7" "Lineage enriched" "Detected in single" 6 "T-cells: 1.7" "Cell line enriched" "Detected in some" 7 "HDLM-2: 57.6" "Not detected" "Not detected" "Region enriched" "Detected in single" 15 "basal ganglia: 13.8" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 44: HDLM-2 - Immune response" "Cluster 28: Keratinocytes - Keratinization" "unprognostic (2.28e-2)" "unprognostic (1.21e-1)" "unprognostic (1.07e-1)" "unprognostic (3.41e-2)" "unprognostic (2.58e-3)" "unprognostic (9.55e-3)" "unprognostic (1.27e-1)" "unprognostic (1.93e-1)" "unprognostic (1.83e-1)" "unprognostic (7.86e-3)" "unprognostic (3.07e-3)" "unprognostic (9.37e-2)" "unprognostic (1.20e-1)" "unprognostic (1.97e-2)" "unprognostic (2.49e-1)" "unprognostic (5.34e-2)" "unprognostic (1.62e-2)" 0.3 1.9 2.1 2.0 0.3 0.5 4.2 0.0 4.0 1.6 0.5 0.4 1.4 0.5 0.0 6.5 0.7 3.1 1.9 3.0 0.0 1.1 0.6 1.3 6.3 0.3 0.0 0.2 1.3 0.0 0.5 0.5 0.2 0.4 0.0 0.7 3.1 0.0 1.3 158.5 0.8 0.0 0.0 1.0 1.9 1.2 0.6 0.1 1.0 0.0 0.3 1.2 3.2 1.0 6.6 0.0 0.1 0.2 0.0 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.0 2.3 0.0 0.0 0.0 57.6 0.0 0.0 2.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 2.3 0.0 1.7 0.2 0.0 7.1 1.2 0.6 0.0 0.2 0.7 0.0 0.0 0.4 0.1 8.6 2.1 1.1 1.4 1.4 2.4 0.0 0.0 0.0 1.6 0.1 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.7 0.1 1.7 0.0 0.6 0.4 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.2 0.9 1.7 2.1 0.3 0.0 4.0 3.0 0.0 0.3 0.0 0.2 0.0 0.6 1.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.9 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.8 34.7 1.1 0.0 0.0 0.0 0.0 THSD7A KIAA0960 ENSG00000005108 "Thrombospondin type 1 domain containing 7A" Q9UPZ6 7 11370365-11832198 "Disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Angiogenesis, Differentiation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 7.5" "Cell type enhanced" "Detected in many" "Astrocytes: 150.5;Bipolar cells: 183.8;Horizontal cells: 208.6;Inhibitory neurons: 494.3;Oligodendrocyte precursor cells: 262.4" "Cancer enhanced" "Detected in many" "renal cancer: 3.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 54 "basophil: 5.3" "Lineage enriched" "Detected in single" 54 "granulocytes: 5.3" "Cell line enhanced" "Detected in some" "A549: 10.3;HUVEC TERT2: 6.7;REH: 7.1;SH-SY5Y: 10.2;THP-1: 19.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000923 Supported "Secreted to blood" NA NA 6100000 "Cluster 38: Basophils - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 43: THP-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA000923: AB_1080271" "unprognostic (3.01e-1)" "unprognostic (7.90e-2)" "unprognostic (3.09e-2)" "unprognostic (1.96e-1)" "unprognostic (5.88e-1)" "unprognostic (3.33e-2)" "unprognostic (1.44e-1)" "unprognostic (9.66e-2)" "unprognostic (1.11e-1)" "unprognostic (1.42e-2)" "unprognostic (2.07e-1)" "unprognostic (8.75e-2)" "prognostic favorable (2.24e-6)" "unprognostic (2.13e-3)" "unprognostic (1.66e-1)" "unprognostic (2.28e-2)" "unprognostic (3.33e-2)" 2.4 0.7 2.9 0.7 2.3 0.0 2.1 3.2 4.4 3.3 0.0 1.0 0.3 2.8 0.8 0.5 2.1 2.6 0.7 4.2 3.5 7.5 0.6 1.1 0.3 2.8 4.9 2.5 0.4 1.2 1.6 4.1 2.5 3.4 0.7 5.0 0.5 2.1 0.2 0.5 0.5 2.4 3.4 0.9 0.5 0.8 4.8 0.2 1.9 1.2 0.2 1.8 1.7 2.4 0.0 10.3 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.6 0.0 0.0 0.0 1.8 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 1.6 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 7.1 0.0 0.0 0.3 0.1 0.7 10.2 0.0 0.3 0.0 1.6 0.1 19.2 3.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 2.3 3.2 4.4 4.2 3.5 2.8 4.9 2.5 3.4 4.8 2.4 46.9 22.4 8.2 150.5 0.0 2.7 1.4 0.0 1.2 183.8 0.8 0.5 1.5 21.5 2.8 55.2 112.6 23.5 0.1 0.4 7.9 7.0 1.2 4.9 22.4 42.6 41.7 0.0 56.6 2.2 4.3 8.1 0.5 18.8 0.0 6.1 28.2 1.3 2.2 208.6 494.3 0.8 0.0 1.5 2.9 0.5 24.2 0.5 12.4 105.9 0.0 20.7 0.0 262.4 5.4 5.5 6.8 1.5 0.1 7.7 0.1 8.8 0.1 9.3 0.0 10.6 5.0 1.6 1.1 0.6 2.4 51.9 0.8 21.5 1.2 1.1 THY1 CD90 ENSG00000154096 "Thy-1 cell surface antigen" P04216 11 119415476-119424985 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 286.8;smooth muscle: 304.7;urinary bladder: 216.7" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 141.6;Excitatory neurons: 116.0;Fibroblasts: 201.9;Inhibitory neurons: 104.1;Muller glia cells: 108.1;Proximal tubular cells: 199.9;Smooth muscle cells: 226.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 461.3;BJ: 738.4;BJ hTERT+: 832.5;fHDF/TERT166: 1330.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003733, CAB068243, CAB068244" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 14000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Plasma membrane" "CAB068243: AB_2665687, CAB068244: AB_2665688, HPA003733: AB_1846340" "unprognostic (9.98e-2)" "unprognostic (2.71e-1)" "unprognostic (5.13e-2)" "unprognostic (2.61e-1)" "prognostic unfavorable (6.87e-4)" "unprognostic (7.43e-2)" "unprognostic (1.43e-3)" "unprognostic (2.38e-2)" "unprognostic (1.29e-1)" "unprognostic (2.90e-3)" "unprognostic (3.38e-2)" "unprognostic (3.52e-1)" "prognostic unfavorable (2.40e-6)" "unprognostic (1.75e-2)" "unprognostic (1.90e-2)" "unprognostic (3.03e-2)" "unprognostic (1.14e-2)" 90.6 16.4 97.9 78.6 114.8 0.2 25.6 12.9 286.8 78.9 0.0 35.4 10.2 58.6 27.8 29.4 23.1 101.0 12.9 135.4 73.3 142.2 7.4 21.6 40.4 83.6 37.0 9.2 14.8 39.4 18.1 62.0 60.8 15.5 41.8 25.3 8.5 47.0 3.4 13.9 14.5 304.7 35.4 21.9 17.4 11.4 43.6 73.2 37.9 8.3 35.6 216.7 21.7 108.7 0.7 3.9 108.5 0.1 461.3 331.5 0.3 738.4 832.5 263.6 289.3 0.2 0.2 0.4 0.1 1330.6 121.9 0.9 4.3 1.1 200.7 65.1 0.0 41.5 14.4 0.0 142.7 0.0 0.2 247.5 0.0 335.6 11.6 355.2 0.3 22.6 0.0 0.6 206.5 0.1 0.6 0.1 173.9 0.0 1.4 0.5 50.7 0.3 0.1 0.2 18.1 47.9 0.1 0.4 0.2 32.9 1.0 2.1 0.0 368.6 120.9 107.3 110.1 0.3 19.7 0.4 1.1 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 97.9 114.8 12.9 286.8 135.4 73.3 83.6 37.0 60.8 35.4 43.6 108.7 68.2 0.0 1.8 17.3 2.1 17.7 0.3 1.7 0.0 27.2 1.6 40.0 0.9 0.0 0.0 9.2 0.0 1.9 0.2 0.0 21.5 0.9 1.0 5.1 141.6 69.2 0.0 0.0 116.0 0.0 2.6 201.9 1.5 3.2 1.3 0.0 17.5 0.1 4.0 32.0 104.1 0.0 0.0 0.0 25.0 2.7 96.3 2.7 17.8 21.5 0.0 108.1 0.0 64.3 22.7 0.4 0.0 77.5 0.1 0.3 0.0 199.9 0.0 27.5 32.9 9.3 226.6 0.3 0.6 0.2 17.6 4.0 4.5 6.2 0.0 0.6 TICRR "C15orf42, FLJ41618, MGC45866, SLD3, Treslin" ENSG00000140534 "TOPBP1 interacting checkpoint and replication regulator" Q7Z2Z1 15 89575469-89631056 "Metabolic proteins, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 3.4;esophagus: 4.2;lymphoid tissue: 4.2" "Cell type enhanced" "Detected in some" "Erythroid cells: 6.5;Extravillous trophoblasts: 6.0;Granulosa cells: 5.1;Spermatocytes: 5.4;Spermatogonia: 5.3;Squamous epithelial cells: 8.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046746, HPA049454" Supported Nucleoplasm NA Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA046746: AB_2732533, HPA049454: AB_2680773" "unprognostic (3.52e-2)" "unprognostic (1.41e-1)" "unprognostic (3.77e-1)" "prognostic unfavorable (4.44e-4)" "unprognostic (3.41e-1)" "unprognostic (1.10e-1)" "unprognostic (6.22e-5)" "unprognostic (7.73e-3)" "prognostic unfavorable (2.87e-6)" "unprognostic (1.64e-1)" "unprognostic (1.31e-4)" "unprognostic (5.87e-2)" "unprognostic (0.00e+0)" "unprognostic (3.54e-2)" "unprognostic (7.38e-2)" "unprognostic (4.53e-2)" "unprognostic (3.59e-2)" 0.3 0.1 0.1 1.0 0.1 3.4 0.3 0.0 0.0 0.5 0.0 0.8 1.0 0.4 0.0 4.2 0.3 0.1 0.1 0.0 0.0 0.1 0.1 0.2 1.4 0.1 0.0 0.3 0.0 0.0 0.1 0.9 0.0 0.2 1.1 0.1 0.5 0.0 0.0 0.5 0.9 0.2 0.1 0.5 0.4 1.5 0.2 4.2 0.1 0.0 1.8 0.3 1.1 0.0 11.0 15.0 19.0 11.0 0.7 1.5 10.7 8.0 3.7 11.0 11.4 16.4 8.4 14.7 4.2 2.6 9.2 21.5 26.3 7.0 10.0 7.4 25.4 21.9 15.5 8.7 0.1 15.8 7.6 0.4 0.5 9.0 6.6 1.6 5.5 12.8 21.3 16.6 6.4 10.4 13.9 13.3 12.7 11.0 7.6 19.6 17.1 11.8 2.6 15.5 8.1 8.0 19.0 10.6 3.1 13.9 7.9 10.5 3.3 11.9 14.8 24.4 16.5 3.9 8.0 12.3 4.1 13.2 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.3 0.3 0.1 0.0 0.2 1.2 0.0 0.3 0.8 1.4 0.0 0.0 0.0 0.0 2.0 0.0 1.4 0.0 0.0 1.7 0.1 0.3 0.3 0.0 6.5 0.4 0.0 6.0 0.5 2.0 0.3 0.0 5.1 0.0 0.0 1.3 0.0 0.6 1.6 0.0 0.0 0.7 1.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.2 0.1 0.0 2.2 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.5 5.4 5.3 8.6 0.1 1.0 0.1 0.1 1.6 0.1 TIPARP "ARTD14, DDF1, DKFZP434J214, DKFZp686N0351, PARP-1, PARP-7, PARP7, pART14, RM1" ENSG00000163659 "TCDD inducible poly(ADP-ribose) polymerase" Q7Z3E1 3 156673235-156706770 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 302.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 53.5" "Lineage enriched" "Detected in all" 5 "granulocytes: 53.5" "Cell line enhanced" "Detected in all" "HBEC3-KT: 168.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036796 Approved Microtubules NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 23: Testis - Cell cycle regulation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" Microtubules "HPA036796: AB_10672268" "prognostic favorable (2.00e-5)" "unprognostic (3.50e-1)" "unprognostic (7.62e-2)" "unprognostic (5.21e-2)" "unprognostic (2.62e-1)" "unprognostic (4.56e-2)" "unprognostic (9.50e-2)" "unprognostic (3.57e-2)" "unprognostic (2.23e-1)" "unprognostic (1.43e-1)" "unprognostic (4.27e-3)" "unprognostic (2.01e-1)" "unprognostic (4.69e-2)" "unprognostic (7.26e-2)" "unprognostic (1.73e-1)" "unprognostic (6.16e-3)" "unprognostic (4.90e-3)" 67.5 56.6 16.5 16.0 19.3 74.1 39.7 17.7 22.3 29.8 15.2 15.1 13.5 30.6 14.7 55.1 39.5 27.9 34.6 16.4 21.2 28.2 44.3 27.4 13.7 33.4 27.9 40.2 29.6 99.2 15.1 12.5 22.9 25.9 14.4 18.3 10.3 27.8 17.6 39.5 23.1 43.7 19.9 10.9 21.9 50.3 25.7 21.7 17.0 9.6 18.1 65.0 24.0 21.9 42.8 29.6 9.8 8.4 35.7 25.9 8.0 70.0 56.4 34.9 48.2 17.2 86.9 12.7 22.2 79.9 46.5 42.1 25.1 168.0 51.4 27.3 18.5 21.0 29.0 11.7 15.2 7.4 38.1 21.3 103.0 35.6 84.9 93.8 32.3 9.4 16.9 49.9 122.5 8.2 6.4 9.8 11.2 53.5 24.5 10.5 22.5 43.6 36.7 20.1 29.5 7.5 55.2 16.9 11.9 22.5 26.2 12.5 70.2 15.1 4.9 28.5 25.1 53.9 10.6 11.3 25.7 11.3 51.4 53.5 5.0 7.5 6.1 3.3 8.6 2.9 5.9 8.2 3.6 5.4 3.6 4.9 15.9 11.6 9.2 5.0 7.4 3.3 16.5 19.3 17.7 22.3 16.4 21.2 33.4 27.9 22.9 19.9 25.7 21.9 112.8 86.6 98.3 27.7 43.9 196.0 117.3 51.7 185.5 5.0 62.0 57.7 29.9 31.5 66.5 7.3 39.6 5.1 97.0 38.3 21.5 35.2 302.3 114.6 118.7 45.6 54.5 7.0 3.6 23.5 10.3 109.0 57.6 169.4 115.0 12.2 20.3 18.9 19.2 21.9 8.7 32.4 18.3 18.5 97.5 28.0 19.6 101.7 37.4 12.2 17.3 10.1 16.5 22.1 20.4 36.9 40.1 19.2 60.5 83.9 40.4 16.2 43.5 10.4 13.1 138.0 87.7 58.0 33.4 100.1 121.5 7.5 105.4 7.3 18.2 187.8 TLCD1 ENSG00000160606 "TLC domain containing 1" Q96CP7 17 28724348-28727935 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 36.4;Syncytiotrophoblasts: 32.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 11 "plasmacytoid DC: 21.7" "Lineage enriched" "Detected in many" 11 "dendritic cells: 21.7" "Cell line enhanced" "Detected in many" "SK-BR-3: 116.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042366 Enhanced NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 27: Brain & Skin - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA042366: AB_10794419" "unprognostic (1.23e-1)" "unprognostic (3.78e-2)" "unprognostic (8.52e-2)" "unprognostic (3.74e-2)" "unprognostic (1.42e-2)" "unprognostic (1.80e-2)" "prognostic unfavorable (3.28e-4)" "unprognostic (2.82e-1)" "unprognostic (1.04e-1)" "unprognostic (4.47e-3)" "unprognostic (9.96e-2)" "unprognostic (1.53e-1)" "prognostic unfavorable (9.05e-5)" "unprognostic (1.56e-1)" "unprognostic (7.56e-2)" "unprognostic (1.86e-2)" "unprognostic (3.93e-2)" 2.6 5.4 14.5 3.2 14.9 1.4 5.2 16.6 21.5 4.4 13.1 8.1 8.1 1.8 13.8 13.1 14.5 2.3 2.3 14.7 14.9 25.9 15.0 7.4 3.2 14.7 15.7 1.1 11.9 3.4 3.9 4.5 14.1 6.5 8.2 1.6 12.9 3.7 0.8 20.6 4.0 1.0 14.7 1.3 8.8 13.1 15.1 4.5 5.3 0.1 9.8 13.8 5.7 13.9 12.4 55.8 14.9 12.7 10.2 18.5 34.6 10.1 17.8 4.7 6.7 31.1 21.3 3.9 15.3 12.1 21.4 19.4 16.6 31.6 7.2 3.1 15.8 6.6 33.4 38.2 10.9 14.0 1.0 12.5 25.4 17.1 30.0 7.3 4.1 1.2 24.3 0.6 8.1 43.5 1.6 5.9 17.0 42.4 10.0 4.6 6.3 23.7 38.9 22.2 28.1 5.6 20.6 116.2 11.3 22.1 57.1 4.9 4.2 4.8 16.2 8.9 16.4 4.0 4.9 9.0 9.1 8.0 16.2 1.9 0.9 0.2 0.2 1.1 0.5 1.4 0.5 0.3 0.9 0.6 0.2 0.3 0.6 0.4 0.7 21.7 0.4 0.4 14.5 14.9 16.6 21.5 14.7 14.9 14.7 15.7 14.1 14.7 15.1 13.9 2.1 0.0 8.4 4.2 2.5 2.4 11.8 23.9 2.2 0.2 19.0 17.1 0.9 7.2 16.6 12.9 0.0 18.3 1.0 7.8 0.0 9.0 17.0 24.1 4.6 1.7 4.8 1.3 0.0 8.3 36.4 4.2 7.1 23.6 0.0 0.9 1.1 18.6 3.5 1.7 0.0 8.8 14.2 0.8 3.7 15.6 1.2 1.5 3.6 0.0 2.1 5.3 0.0 1.0 0.0 10.5 4.5 0.4 1.8 23.7 8.5 6.9 31.0 0.7 0.0 2.0 8.8 20.2 7.2 8.4 2.0 32.3 2.2 3.0 8.0 23.1 TLCD4 "FLJ31842, TMEM56" ENSG00000152078 "TLC domain containing 4" Q96MV1 1 95117355-95197607 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 130.0" "Cell type enriched" "Detected in some" 9 "Cardiomyocytes: 77.9" "Cancer enhanced" "Detected in many" "liver cancer: 13.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 22.4;RH-30: 35.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046762 Approved "Nuclear speckles" No No "Cluster 19: B-cells - Humoral immune response" "Cluster 85: Liver - Metabolism" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nuclear speckles" "HPA046762: AB_2679792" "unprognostic (1.51e-3)" "unprognostic (1.54e-1)" "unprognostic (2.98e-3)" "unprognostic (2.79e-1)" "unprognostic (3.30e-2)" "unprognostic (2.31e-1)" "unprognostic (3.82e-3)" "unprognostic (3.63e-2)" "unprognostic (4.42e-3)" "unprognostic (2.69e-2)" "unprognostic (4.99e-2)" "unprognostic (4.40e-2)" "unprognostic (1.16e-3)" "unprognostic (1.10e-1)" "unprognostic (9.46e-2)" "unprognostic (1.59e-1)" "unprognostic (3.15e-2)" 5.3 9.9 9.4 2.1 10.6 20.5 2.6 19.5 15.1 2.4 0.0 13.6 5.5 3.4 2.5 2.3 2.4 4.2 25.7 10.6 6.3 5.7 130.0 3.7 0.4 4.9 5.7 1.7 7.4 6.4 3.4 4.4 4.2 5.3 10.2 3.1 8.3 2.9 13.0 1.6 8.5 3.6 6.9 0.7 5.0 4.8 9.9 0.3 7.3 9.7 0.5 4.7 1.3 12.6 22.4 12.6 1.7 2.6 0.8 0.0 2.9 0.8 0.5 2.8 6.5 9.1 10.4 0.0 10.7 0.4 20.0 0.2 7.4 1.1 4.8 15.5 4.1 0.5 9.2 2.0 0.8 0.4 0.6 1.2 0.4 2.1 0.0 4.4 0.0 1.2 19.8 1.2 0.6 1.9 1.3 0.1 1.7 0.7 6.9 0.0 35.7 0.6 12.0 14.4 4.5 3.6 15.6 10.8 6.7 1.8 11.7 0.4 0.2 0.3 9.0 1.1 7.9 3.8 8.0 0.0 1.5 0.1 2.3 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 9.4 10.6 19.5 15.1 10.6 6.3 4.9 5.7 4.2 6.9 9.9 12.6 5.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 77.9 0.0 0.0 0.0 0.0 8.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.5 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 TM7SF2 "ANG1, DHCR14A, NET47" ENSG00000149809 "Transmembrane 7 superfamily member 2" O76062 11 65111845-65116384 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 246.0" "Cell type enhanced" "Detected in all" "Granulosa cells: 482.7;Hepatocytes: 220.6;Muller glia cells: 204.7;Theca cells: 204.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 38.1" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MCF7: 69.2;RPTEC TERT1: 86.2;T-47d: 143.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030691, HPA072704" Enhanced Supported "Endoplasmic reticulum,Vesicles" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 40: Granulosa cells - Unknown function" "Endoplasmic reticulum" Vesicles "HPA030691: AB_10602480, HPA072704: AB_2686551" "unprognostic (1.62e-1)" "unprognostic (5.23e-2)" "unprognostic (1.70e-2)" "unprognostic (1.78e-1)" "unprognostic (5.74e-2)" "unprognostic (1.10e-1)" "unprognostic (5.98e-2)" "unprognostic (6.06e-2)" "unprognostic (5.72e-2)" "unprognostic (1.74e-2)" "unprognostic (7.06e-2)" "unprognostic (1.69e-1)" "prognostic favorable (8.49e-8)" "unprognostic (8.77e-2)" "unprognostic (1.90e-1)" "unprognostic (1.35e-1)" "unprognostic (3.44e-2)" 63.4 246.0 27.8 2.6 28.5 4.1 29.1 32.8 33.9 17.4 64.1 7.8 9.4 3.4 17.0 39.6 12.8 7.0 47.3 30.0 29.7 18.9 86.4 10.1 3.4 34.0 32.0 36.5 69.9 36.3 19.5 3.9 32.5 41.1 3.9 6.0 46.9 6.0 7.1 68.2 8.3 1.9 30.1 5.1 35.6 11.5 32.6 5.6 15.5 3.7 8.4 5.5 22.1 35.1 7.7 10.9 27.3 35.1 8.1 1.3 15.4 1.8 4.5 2.7 3.0 26.0 35.8 16.3 26.9 2.2 1.0 13.3 11.6 21.2 1.9 16.7 5.0 10.2 2.7 54.5 18.8 4.2 10.6 3.7 5.0 14.6 3.9 12.6 3.9 28.7 5.8 13.9 0.8 69.2 8.3 18.6 12.6 18.4 11.2 22.4 1.2 39.9 86.2 12.6 27.2 30.5 1.2 28.2 6.1 19.5 143.9 11.4 3.1 0.4 3.4 3.8 2.3 27.1 18.1 8.4 2.5 5.9 1.0 1.1 1.6 3.4 9.1 1.5 7.0 12.4 5.6 7.8 1.5 11.9 11.8 9.0 1.1 12.5 0.9 38.1 5.6 4.9 27.8 28.5 32.8 33.9 30.0 29.7 34.0 32.0 32.5 30.1 32.6 35.1 4.0 9.6 43.7 23.5 12.7 1.9 6.2 33.6 5.7 19.2 52.2 38.5 99.4 52.9 36.6 44.1 10.4 72.9 16.3 23.3 17.6 27.1 28.8 17.9 2.6 5.7 59.4 13.7 11.6 27.7 4.6 4.3 31.1 16.5 7.0 482.7 5.0 220.6 15.6 25.2 15.3 21.8 52.9 6.3 2.7 59.3 9.9 5.8 12.4 2.8 9.4 204.7 7.2 17.1 36.5 21.7 23.7 2.2 12.9 31.3 29.0 77.5 37.9 23.6 13.1 1.6 21.8 13.3 17.9 18.0 7.0 82.1 8.3 204.8 19.0 10.4 TMEM11 "C17orf35, PM1, PMI" ENSG00000178307 "Transmembrane protein 11" P17152 17 21197954-21214176 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 81.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051795, HPA062854" Uncertain Supported Mitochondria No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA051795: AB_2681612, HPA062854: AB_2684882" "unprognostic (2.29e-1)" "unprognostic (1.09e-1)" "unprognostic (1.13e-2)" "unprognostic (2.00e-2)" "unprognostic (1.35e-2)" "unprognostic (3.55e-1)" "unprognostic (3.36e-3)" "unprognostic (1.45e-2)" "unprognostic (4.34e-2)" "unprognostic (3.08e-2)" "unprognostic (1.16e-1)" "unprognostic (1.90e-2)" "unprognostic (1.40e-1)" "unprognostic (1.19e-1)" "unprognostic (1.97e-1)" "unprognostic (2.17e-2)" "unprognostic (4.61e-2)" 17.6 11.7 18.9 12.4 19.3 37.7 10.8 21.1 25.1 10.6 18.4 13.9 12.5 11.8 18.6 14.2 9.4 9.0 21.3 19.1 19.9 9.9 9.9 11.8 13.8 20.3 19.3 12.2 30.4 14.9 1.3 17.1 19.8 12.2 10.0 10.9 23.7 9.1 81.3 16.8 14.2 9.8 18.7 11.5 13.2 7.7 19.8 15.8 12.6 54.1 9.8 15.6 1.9 19.8 25.3 27.5 22.7 22.1 33.9 24.1 31.2 38.9 17.7 35.8 31.3 74.5 13.5 27.4 29.7 36.3 29.0 35.0 30.0 35.8 17.9 23.2 46.5 19.8 27.0 32.1 36.8 25.1 22.0 26.5 27.7 36.4 26.2 17.2 22.8 19.3 23.0 9.5 26.9 39.9 37.8 46.6 30.5 68.8 15.3 27.2 49.8 19.6 25.2 21.3 13.8 24.0 17.6 19.0 36.9 87.2 18.4 24.8 21.4 25.1 29.7 42.5 49.3 9.6 13.2 69.3 24.9 31.9 22.6 31.2 70.6 76.2 33.1 58.9 29.6 49.4 33.1 31.8 47.1 47.4 37.0 31.8 58.4 40.8 67.9 38.8 40.3 68.1 18.9 19.3 21.1 25.1 19.1 19.9 20.3 19.3 19.8 18.7 19.8 19.8 35.0 48.1 21.8 5.5 26.0 84.9 61.9 77.7 35.3 32.9 40.2 39.9 49.9 22.8 49.1 36.8 18.8 80.7 36.6 49.4 50.9 55.3 20.7 23.9 23.6 36.8 31.9 51.3 4.4 40.5 80.9 33.9 20.9 29.1 27.3 23.1 32.2 28.1 54.3 23.5 5.1 67.4 73.2 25.3 34.5 16.3 35.8 26.3 40.9 8.4 48.6 31.6 33.0 6.0 8.0 47.4 60.6 57.6 19.9 63.6 55.0 55.9 33.0 39.9 32.9 25.7 42.0 40.4 38.4 34.7 92.6 90.8 28.7 31.3 49.6 80.2 TMEM167B "AD-020, C1orf119, FLJ90710" ENSG00000215717 "Transmembrane protein 167B" Q9NRX6 1 109090764-109096934 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 30: Epithelial cell lines - Translation" "Cluster 16: Pancreatic endocrine cells - Mixed function" "unprognostic (7.89e-2)" "unprognostic (3.28e-1)" "unprognostic (4.96e-2)" "prognostic favorable (8.86e-4)" "unprognostic (3.76e-1)" "unprognostic (1.19e-1)" "unprognostic (1.41e-3)" "unprognostic (2.37e-2)" "unprognostic (1.28e-1)" "unprognostic (7.20e-2)" "unprognostic (1.74e-1)" "unprognostic (3.01e-1)" "unprognostic (3.21e-2)" "unprognostic (1.43e-1)" "unprognostic (1.94e-1)" "unprognostic (1.15e-2)" "unprognostic (2.25e-1)" 31.7 35.5 29.9 24.2 30.3 53.7 33.1 30.0 34.4 32.4 29.6 27.7 23.2 30.9 31.6 24.0 25.4 25.6 35.9 30.1 30.5 33.3 33.0 28.4 26.2 29.1 30.2 29.7 25.7 45.1 15.9 33.8 29.6 36.9 29.8 31.3 30.3 27.9 21.3 28.9 23.7 30.6 31.3 28.3 32.4 23.4 30.9 25.1 41.7 25.9 27.7 27.2 16.3 33.0 36.1 6.5 23.4 32.3 47.8 47.0 20.9 54.2 49.7 30.0 27.8 13.7 13.4 24.0 30.1 55.9 17.8 17.4 15.1 24.1 43.0 37.4 11.4 22.4 8.7 18.8 53.6 43.6 36.6 38.8 64.7 27.9 46.7 40.8 26.5 30.8 28.5 33.9 33.0 22.2 33.0 28.1 17.7 31.0 33.1 20.5 37.1 19.0 38.6 22.5 16.6 17.0 26.2 38.0 53.0 20.8 23.7 32.0 25.2 30.6 30.8 67.0 26.6 34.0 20.6 23.7 51.7 44.7 65.0 38.1 20.7 35.4 13.3 23.8 19.1 14.4 17.6 17.0 19.1 13.5 17.8 17.8 45.4 17.5 30.8 11.7 17.9 19.9 29.9 30.3 30.0 34.4 30.1 30.5 29.1 30.2 29.6 31.3 30.9 33.0 29.6 32.1 31.4 10.7 30.1 30.5 29.4 25.7 16.5 30.1 28.2 17.9 34.0 22.8 28.6 18.4 12.5 42.1 38.7 20.0 19.6 26.7 19.1 16.2 25.2 30.7 20.9 25.9 11.5 30.1 44.3 32.3 23.0 27.1 32.3 21.7 27.8 21.7 39.1 25.2 12.5 25.2 24.4 36.8 42.8 17.0 28.9 38.8 26.6 6.5 56.3 36.0 24.7 12.5 16.4 29.3 19.7 25.2 16.8 39.8 25.9 29.6 19.7 30.1 0.0 21.7 26.8 28.9 28.2 26.0 35.7 63.1 32.9 20.4 19.1 51.5 TMEM210 ENSG00000185863 "Transmembrane protein 210" A6NLX4 9 137170858-137172056 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "testis: 14.8" "Group enriched" "Detected in some" 68 "Early spermatids: 900.5;Late spermatids: 1815.1" "Cancer enhanced" "Detected in single" "prostate cancer: 1.2" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 33 "plasmacytoid DC: 3.2" "Lineage enriched" "Detected in single" 33 "dendritic cells: 3.2" "Cell line enriched" "Detected in some" 8 "RPMI-8226: 13.5" "Not detected" "Not detected" HPA066907 Enhanced NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 25: RPMI-8226 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "HPA066907: AB_2685747" "unprognostic (5.17e-2)" "unprognostic (5.04e-2)" "unprognostic (2.87e-5)" "unprognostic (4.18e-2)" "unprognostic (3.63e-2)" "unprognostic (3.14e-2)" "unprognostic (8.00e-2)" 0.0 0.0 0.1 0.0 0.3 0.0 0.3 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.0 1.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 13.5 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.1 0.3 0.3 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 1.6 1.3 0.0 0.0 0.1 0.0 0.0 0.0 8.1 0.0 0.0 0.0 900.5 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.7 1815.1 12.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 6.4 0.0 1.1 0.0 0.0 0.0 0.0 19.7 0.0 0.1 9.1 4.9 0.0 0.1 0.0 0.1 0.0 0.0 0.2 TMEM271 ENSG00000273238 "Transmembrane protein 271" A0A286YF58 4 573880-576295 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 6 "brain: 23.3" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "glioma: 1.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "JURKAT: 1.7;NB-4: 1.5;NTERA-2: 2.6;SCLC-21H: 5.7;U-2 OS: 1.4;U-251 MG: 1.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 7: SCLC-21H - Neuronal signaling" "unprognostic (4.13e-3)" "unprognostic (6.97e-3)" "unprognostic (2.65e-2)" 0.0 0.9 13.2 0.0 12.4 0.0 0.0 0.2 23.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.0 11.2 0.0 0.0 0.0 0.0 4.0 5.1 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.2 0.0 0.0 0.0 3.7 0.0 0.0 2.4 0.0 0.0 0.1 6.2 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.7 1.5 2.6 0.0 0.0 0.0 0.6 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.4 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.2 12.4 0.2 23.3 18.0 11.2 4.0 5.1 2.7 2.4 6.2 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TMIGD3 AD026 ENSG00000121933 "Transmembrane and immunoglobulin domain containing 3" P0DMS9 1 111483348-111563962 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "testis: 55.1" "Cell type enhanced" "Detected in some" "Early spermatids: 272.5;Hofbauer cells: 236.3;Kupffer cells: 161.3;Late spermatids: 118.9;Spermatocytes: 198.3" "Cancer enriched" "Detected in all" 5 "glioma: 16.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 44 "eosinophil: 62.8" "Lineage enriched" "Detected in many" 44 "granulocytes: 62.8" "Cell line enhanced" "Detected in some" "HDLM-2: 7.0;HMC-1: 2.5;Karpas-707: 1.2;NB-4: 3.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 78: Testis - Spermatogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 4: Macrophages - Innate immune response" "prognostic unfavorable (3.58e-4)" "unprognostic (7.64e-3)" "unprognostic (7.47e-3)" "unprognostic (2.11e-2)" "unprognostic (6.74e-2)" "unprognostic (9.79e-2)" "unprognostic (9.48e-2)" "unprognostic (5.70e-2)" "unprognostic (1.01e-1)" "unprognostic (2.07e-3)" "unprognostic (4.46e-2)" "unprognostic (9.50e-2)" "unprognostic (4.48e-2)" "unprognostic (5.69e-3)" "unprognostic (3.30e-1)" "unprognostic (1.44e-5)" "unprognostic (9.22e-2)" 0.8 3.3 1.7 1.3 3.0 2.0 0.8 2.2 3.2 0.6 1.2 0.8 0.3 0.2 0.0 0.7 0.4 0.7 0.4 2.3 2.6 0.2 2.6 0.7 0.9 4.4 4.5 0.2 0.2 0.4 0.2 4.6 4.8 0.3 0.5 0.3 0.3 1.3 0.1 0.1 1.5 0.8 3.0 1.4 0.6 55.1 3.9 0.6 0.2 0.5 0.4 0.4 0.2 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 7.0 0.0 0.0 0.0 0.0 0.0 0.2 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.1 3.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 62.8 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.4 0.3 0.3 0.6 0.0 0.6 1.7 3.0 2.2 3.2 2.3 2.6 4.4 4.5 4.8 3.0 3.9 6.1 1.0 0.0 2.3 0.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.5 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 272.5 0.0 0.0 5.1 0.0 2.7 0.7 0.2 1.9 0.3 0.0 0.0 0.0 0.0 5.3 1.2 236.3 0.0 0.7 0.0 0.0 161.3 0.0 118.9 3.7 59.5 0.0 29.0 1.3 0.5 0.0 0.5 4.4 0.0 0.0 1.2 0.0 0.1 0.0 0.5 0.0 0.3 13.1 0.0 0.1 198.3 2.6 0.1 0.0 2.9 0.7 0.2 0.0 0.1 TMPO "LAP2, LEMD4, TP" ENSG00000120802 Thymopoietin "P42166, P42167" 12 98515579-98550351 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" DNA-binding Cardiomyopathy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 139.9" "Cell type enhanced" "Detected in all" "Erythroid cells: 172.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008150, CAB009847, HPA070805" Enhanced Enhanced "Nuclear membrane" NA Yes 190000 "Cluster 51: Monocytes - Innate immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear membrane" "CAB009847: AB_2205450, HPA008150: AB_1079235, HPA070805: " "unprognostic (2.36e-1)" "unprognostic (4.46e-3)" "unprognostic (5.90e-2)" "unprognostic (2.80e-2)" "unprognostic (1.35e-1)" "unprognostic (2.95e-2)" "unprognostic (1.07e-2)" "unprognostic (1.54e-1)" "unprognostic (1.74e-2)" "unprognostic (3.69e-1)" "unprognostic (1.02e-1)" "unprognostic (3.67e-3)" "prognostic unfavorable (9.34e-4)" "unprognostic (6.01e-3)" "unprognostic (2.85e-1)" "unprognostic (5.26e-2)" "unprognostic (3.26e-2)" 17.1 13.9 8.4 44.0 9.4 93.2 24.3 19.1 15.1 23.2 10.1 34.5 34.1 30.8 34.4 27.0 22.8 17.7 11.0 9.1 9.6 21.7 37.2 21.9 78.7 9.7 8.9 56.2 25.3 17.8 8.4 29.4 9.6 17.2 36.4 20.7 16.5 19.1 12.2 22.7 39.6 22.3 8.8 39.1 35.7 23.1 9.6 139.9 15.2 12.2 78.1 20.7 20.7 14.2 180.5 117.5 283.3 145.5 23.1 30.7 166.2 145.0 77.1 193.9 139.5 129.5 88.9 314.4 86.2 85.6 70.7 113.0 240.8 110.1 177.1 217.7 148.5 269.1 103.3 86.5 21.2 315.4 170.8 17.6 35.4 115.0 61.2 66.9 112.8 192.0 231.8 118.1 122.0 114.7 514.9 248.6 170.1 167.2 108.6 421.3 187.2 218.6 69.3 167.7 221.9 132.2 248.9 155.2 79.3 110.6 174.3 149.2 60.4 111.1 96.5 76.8 150.8 125.9 231.9 344.0 32.0 179.5 151.0 48.6 30.4 13.4 18.9 54.1 20.5 22.4 21.9 21.6 23.4 27.2 30.0 23.5 2.4 20.7 75.9 12.9 28.5 30.5 8.4 9.4 19.1 15.1 9.1 9.6 9.7 8.9 9.6 8.8 9.6 14.2 45.4 32.1 27.9 3.6 70.1 27.8 23.7 18.7 28.5 21.1 21.2 28.6 9.0 25.8 33.5 31.3 12.5 36.0 48.5 63.0 31.3 19.5 42.7 29.5 29.8 38.0 28.7 172.1 20.3 31.5 89.7 32.2 56.1 42.7 29.1 70.1 34.2 50.0 38.2 10.1 15.3 63.4 16.2 63.1 34.9 32.1 28.6 73.4 17.8 23.4 63.5 20.3 54.6 14.6 19.1 26.7 28.5 40.6 81.9 21.1 33.7 33.1 25.6 52.6 19.7 27.3 32.0 54.0 59.4 62.8 23.3 11.8 60.8 32.4 62.4 21.8 TNFRSF19 "TAJ, TAJ-alpha, TRADE, TROY" ENSG00000127863 "TNF receptor superfamily member 19" Q9NS68 13 23570370-23676104 "Plasma proteins, Predicted membrane proteins" Apoptosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 55.3;skin 1: 107.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 62.2;Microglial cells: 71.2;Respiratory ciliated cells: 62.4;Suprabasal keratinocytes: 80.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC TERT1: 46.5;BJ hTERT+: 73.2;fHDF/TERT166: 55.9;Hep G2: 83.0;SK-MEL-30: 128.4;WM-115: 76.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010135 Approved Nucleoplasm,Mitochondria No No "Cluster 35: T-regs - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 28: Keratinocytes - Keratinization" Mitochondria Nucleoplasm "HPA010135: AB_1079797" "unprognostic (5.70e-2)" "unprognostic (1.28e-1)" "unprognostic (1.17e-2)" "unprognostic (2.42e-1)" "unprognostic (2.04e-1)" "unprognostic (1.86e-3)" "unprognostic (2.01e-2)" "prognostic favorable (3.87e-4)" "unprognostic (3.74e-1)" "unprognostic (5.47e-2)" "unprognostic (4.41e-2)" "unprognostic (6.56e-2)" "prognostic favorable (9.13e-7)" "unprognostic (3.44e-2)" "unprognostic (6.05e-2)" "unprognostic (3.25e-3)" "unprognostic (5.38e-3)" 1.8 2.9 1.8 0.9 1.7 1.7 9.9 1.8 1.9 7.0 4.2 2.4 1.8 8.6 13.4 9.4 30.5 3.4 22.1 2.0 2.5 15.7 1.1 17.2 0.7 3.3 3.2 2.7 2.8 0.9 8.5 8.4 2.6 27.4 1.9 4.7 55.3 7.6 2.4 107.5 1.3 3.0 3.1 5.1 5.4 2.2 2.7 6.7 3.4 2.1 1.8 4.5 4.8 2.5 0.1 3.3 3.2 0.0 4.7 46.5 3.5 3.7 73.2 2.0 2.8 23.6 0.1 0.0 0.0 55.9 0.5 0.1 3.3 2.9 3.6 0.0 2.9 0.6 2.4 83.0 2.2 0.2 0.9 22.5 0.7 23.1 0.3 1.5 0.1 0.0 0.1 0.0 13.2 1.1 0.0 0.1 2.3 29.7 5.1 0.0 13.6 0.0 8.4 0.4 30.9 4.9 0.1 0.0 128.4 3.4 0.0 0.3 0.0 11.5 0.5 0.1 3.5 0.0 0.1 0.0 4.5 0.1 76.2 0.0 0.0 0.2 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.2 1.3 0.0 1.8 1.7 1.8 1.9 2.0 2.5 3.3 3.2 2.6 3.1 2.7 2.5 3.1 0.0 20.8 1.0 0.2 62.2 3.0 2.0 23.9 0.8 6.3 2.9 23.4 2.8 9.3 9.2 8.4 0.1 0.3 0.1 0.0 11.1 1.7 10.4 4.4 5.1 0.0 0.0 6.9 1.0 0.0 14.4 2.6 3.9 1.3 0.5 0.0 0.5 0.1 0.0 6.7 0.0 6.1 0.0 8.5 1.0 11.5 0.2 14.2 71.2 0.0 3.3 0.0 12.5 1.1 11.3 0.0 13.9 0.0 13.3 0.0 20.9 62.4 3.3 0.0 3.2 4.9 1.5 2.3 8.3 80.3 0.0 0.6 3.5 0.0 0.6 TNNC1 TNNC ENSG00000114854 "Troponin C1, slow skeletal and cardiac type" P63316 3 52451100-52454041 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Muscle protein" "Cardiomyopathy, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 36 "heart muscle: 8734.3;skeletal muscle: 21081.1;tongue: 12403.9" "Cell type enriched" "Detected in many" 10 "Cardiomyocytes: 3550.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 27.1" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "MAIT T-cell: 1.2" "Lineage enriched" "Detected in single" 6 "T-cells: 1.2" "Cell line enhanced" "Detected in many" "CACO-2: 68.2;CAPAN-2: 33.5;EFO-21: 65.2;HeLa: 49.1;Hep G2: 46.1;HSkMC: 67.2;U-2 OS: 97.7" "Region enriched" "Detected in all" 4 "cerebral cortex: 87.0" "Group enriched" "Detected in some" 6 "midbrain: 7.6;spinal cord: 7.1" "CAB002450, HPA044848, HPA056897" Enhanced Approved "Nucleoplasm,Actin filaments,Mitochondria" NA NA 990000 "Cluster 13: T-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 9: U-2 OS - Unknown function" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nucleoplasm, Actin filaments, Mitochondria" "CAB002450: AB_564152, HPA044848: AB_2679110, HPA056897: AB_2683269" "unprognostic (2.18e-2)" "unprognostic (1.70e-1)" "unprognostic (8.66e-2)" "unprognostic (3.43e-1)" "unprognostic (4.00e-2)" "unprognostic (1.88e-2)" "unprognostic (1.11e-1)" "unprognostic (1.43e-1)" "unprognostic (1.53e-1)" "unprognostic (3.92e-1)" "unprognostic (1.03e-1)" "unprognostic (1.07e-1)" "unprognostic (2.15e-2)" "unprognostic (4.95e-2)" "unprognostic (2.31e-1)" "unprognostic (4.15e-2)" "unprognostic (4.86e-1)" 8.4 10.9 0.7 0.8 0.8 0.7 19.1 2.7 1.1 7.7 7.3 4.0 1.1 2.8 41.7 387.3 2.8 3.3 8734.3 1.2 0.7 19.2 4.0 78.5 3.9 0.8 0.9 2.4 6.8 1.6 17.6 5.2 1.0 170.1 4.1 0.4 120.8 2.2 21081.1 18.9 3.3 0.8 0.8 2.8 5.7 10.6 0.8 4.3 14.4 12403.9 1.6 5.3 5.4 0.7 0.7 5.2 3.6 0.6 0.2 0.5 8.0 0.4 0.3 0.3 0.4 68.2 33.5 0.5 65.2 9.9 0.1 0.4 0.1 0.3 0.0 1.2 1.6 0.5 49.1 46.1 0.3 0.3 0.1 67.2 1.2 0.0 0.7 0.6 0.0 2.0 0.2 5.1 2.0 0.1 0.2 0.8 0.5 15.1 0.7 0.1 2.9 2.3 3.3 13.0 0.2 0.0 0.5 6.7 0.1 3.9 26.7 0.5 0.0 0.1 97.7 0.8 0.2 2.8 1.3 0.9 0.3 0.7 0.1 0.0 0.0 0.0 0.2 0.0 1.2 0.0 0.2 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.1 0.8 0.1 0.7 0.8 2.7 1.1 1.2 0.7 0.8 0.9 1.0 0.8 0.8 0.7 0.2 125.0 12.6 0.0 0.3 1.5 1.7 4.0 0.6 0.2 0.5 0.3 3550.1 5.7 7.9 3.7 2.1 59.0 0.1 1.6 27.4 11.8 0.7 66.4 6.7 39.8 330.7 0.4 0.0 13.0 5.1 52.7 0.5 98.8 0.0 0.8 0.7 0.7 4.9 0.0 0.0 1.7 2.0 0.0 1.4 5.8 22.4 2.6 5.4 0.0 0.1 1.2 0.0 0.0 0.0 6.5 0.3 177.6 0.1 0.8 0.5 1.3 2.8 0.1 0.0 241.8 36.0 2.1 1.0 0.1 0.9 31.1 2.8 1.3 2.0 6.8 TOLLIP IL-1RAcPIP ENSG00000078902 "Toll interacting protein" Q9H0E2 11 1274371-1309654 "Plasma proteins, Predicted intracellular proteins" "Autophagy, Immunity, Inflammatory response, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 498.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038621, HPA038622" Enhanced Approved Cytosol NA NA 140000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "HPA038621: AB_10673177, HPA038622: AB_10675946" "unprognostic (8.39e-2)" "unprognostic (1.89e-1)" "unprognostic (2.18e-2)" "unprognostic (6.08e-2)" "prognostic unfavorable (5.45e-4)" "unprognostic (8.89e-2)" "unprognostic (2.51e-1)" "unprognostic (8.53e-2)" "unprognostic (2.17e-1)" "unprognostic (1.55e-2)" "unprognostic (1.90e-2)" "unprognostic (2.74e-1)" "prognostic favorable (1.11e-16)" "unprognostic (2.72e-1)" "unprognostic (1.46e-1)" "unprognostic (3.21e-2)" "unprognostic (1.29e-2)" 26.8 35.4 58.2 12.4 73.5 13.6 25.8 27.5 80.9 35.9 17.6 26.3 25.5 23.5 11.5 93.4 22.4 18.4 31.3 85.0 39.4 43.1 113.3 26.6 14.2 39.9 39.1 24.6 58.2 18.9 54.2 12.1 39.8 31.4 8.2 11.4 31.6 20.5 76.2 75.9 23.4 11.1 32.9 28.8 31.9 73.4 42.7 13.2 24.7 22.7 14.2 33.5 48.8 56.5 31.4 32.6 16.3 18.6 34.0 21.2 14.2 27.2 24.5 31.3 27.7 35.4 19.5 14.6 25.6 25.3 47.9 27.7 14.7 33.4 8.5 30.1 30.1 11.9 6.9 54.2 48.4 22.8 29.0 32.1 38.5 18.6 17.9 17.1 19.7 21.7 19.9 38.5 26.1 26.3 29.1 27.9 20.0 33.9 42.1 21.8 16.6 14.6 20.9 41.3 43.5 25.5 24.4 29.4 30.7 8.3 23.3 25.7 36.0 33.8 14.4 14.4 16.0 38.8 37.8 18.3 53.2 14.9 27.0 45.4 126.6 139.6 33.4 114.0 27.8 38.8 35.3 31.5 99.9 50.0 27.4 26.1 179.1 44.5 108.8 52.4 48.8 77.3 58.2 73.5 27.5 80.9 85.0 39.4 39.9 39.1 39.8 32.9 42.7 56.5 19.5 9.6 19.3 15.0 27.8 66.9 43.9 71.7 23.3 42.6 30.3 24.6 22.8 58.6 30.9 23.9 8.4 49.2 28.0 50.8 70.5 66.3 173.6 11.7 14.8 24.9 51.6 45.0 35.1 69.2 41.1 27.6 19.4 15.8 38.1 20.7 37.9 112.2 92.1 74.0 17.0 30.8 48.8 38.4 33.1 498.2 21.8 48.3 71.2 16.9 50.6 38.1 19.6 10.6 15.0 76.3 53.7 30.9 33.4 55.7 66.6 110.1 15.4 20.6 6.6 18.5 24.5 100.7 39.6 76.3 98.9 104.4 22.0 27.4 29.3 74.0 TPPP "p25, p25alpha, TPPP/p25, TPPP1" ENSG00000171368 "Tubulin polymerization promoting protein" O94811 5 659862-693352 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 185.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 38.5;Excitatory neurons: 45.2;Horizontal cells: 42.1;Inhibitory neurons: 32.6;Oligodendrocytes: 104.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 7.4;AN3-CA: 5.4;SCLC-21H: 13.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036575, HPA036576" Enhanced Supported Mitochondria,Cytosol NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Mitochondria, Cytosol" "HPA036575: AB_10673501, HPA036576: AB_2675200" "unprognostic (3.66e-2)" "unprognostic (3.70e-3)" "unprognostic (9.98e-3)" "unprognostic (7.82e-2)" "unprognostic (2.05e-2)" "unprognostic (3.20e-2)" "unprognostic (2.12e-1)" "unprognostic (3.80e-3)" "unprognostic (3.85e-1)" "unprognostic (1.63e-1)" "unprognostic (2.07e-3)" "unprognostic (5.48e-2)" "prognostic favorable (5.40e-6)" "unprognostic (4.03e-2)" "unprognostic (2.30e-1)" "unprognostic (2.03e-2)" "unprognostic (3.31e-2)" 3.8 6.6 100.8 0.7 136.7 0.2 2.5 55.3 120.4 1.8 0.0 12.8 5.2 3.3 0.5 11.0 10.4 1.7 9.8 112.3 69.9 4.4 2.7 10.2 0.3 110.3 102.3 1.8 6.0 2.1 19.5 2.2 107.7 2.3 1.8 6.3 5.7 3.6 10.5 8.2 9.5 3.6 47.5 2.6 4.9 2.2 124.6 0.4 6.9 5.3 1.4 6.8 2.7 185.2 0.2 7.4 0.3 5.4 0.8 0.0 1.0 0.1 0.0 0.0 0.0 0.3 0.8 0.1 0.5 0.0 1.9 2.9 2.9 0.0 0.0 1.5 2.5 0.2 3.6 0.2 0.8 0.2 0.3 0.0 0.7 0.0 0.1 0.2 0.0 0.1 0.1 2.7 0.0 0.2 0.2 0.5 0.2 0.8 0.7 0.3 0.1 1.0 0.2 1.0 13.2 1.6 0.8 0.3 3.6 0.3 0.7 0.2 0.1 0.2 2.7 0.0 0.2 1.0 0.2 0.0 0.5 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 100.8 136.7 55.3 120.4 112.3 69.9 110.3 102.3 107.7 47.5 124.6 185.2 1.6 38.5 10.0 6.8 0.7 4.1 1.4 0.6 9.6 21.3 3.1 2.4 18.4 2.8 5.3 1.8 0.0 0.0 1.1 5.7 1.9 2.4 9.1 26.6 0.9 2.0 10.2 0.0 45.2 0.7 0.3 3.3 3.1 5.8 4.5 0.1 2.2 4.3 3.3 42.1 32.6 6.5 0.0 0.0 2.2 7.2 0.3 1.2 1.8 4.7 0.1 0.9 0.0 6.6 104.7 0.7 5.2 0.4 3.3 0.8 10.3 1.1 13.5 2.4 0.0 1.5 4.2 2.2 0.8 6.7 3.1 0.0 4.8 0.1 4.8 4.1 TPX2 "C20orf1, C20orf2, DIL-2, p100" ENSG00000088325 "TPX2 microtubule nucleation factor" Q9ULW0 20 31739271-31801805 "Cancer-related genes, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Mitosis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 48.0;lymphoid tissue: 70.3;testis: 30.7" "Cell type enhanced" "Detected in many" "Erythroid cells: 90.7;Extravillous trophoblasts: 68.5;Granulosa cells: 46.6;Spermatocytes: 114.5;Spermatogonia: 63.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "T-reg: 8.1" "Group enriched" "Detected in many" 5 "granulocytes: 5.1;NK-cells: 3.6;T-cells: 8.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005487 Enhanced Supported "Nucleoplasm,Cytokinetic bridge,Mitotic spindle" Yes Yes "Cluster 44: Non-specific - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Cytokinetic bridge, Mitotic spindle" "HPA005487: AB_1858223" "unprognostic (2.18e-2)" "unprognostic (1.77e-1)" "unprognostic (1.97e-2)" "prognostic unfavorable (2.43e-6)" "unprognostic (2.99e-1)" "unprognostic (7.56e-2)" "prognostic unfavorable (8.07e-7)" "prognostic unfavorable (6.46e-4)" "unprognostic (3.70e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (2.68e-5)" "unprognostic (5.99e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (4.56e-2)" "unprognostic (2.30e-1)" "unprognostic (1.76e-2)" "unprognostic (1.39e-1)" 1.9 1.4 0.9 13.0 0.9 48.0 2.7 0.8 1.0 2.3 0.5 11.6 9.4 2.4 0.2 13.2 0.9 1.8 0.8 1.1 0.6 0.7 4.2 1.9 26.6 0.6 1.0 0.5 0.4 0.4 0.2 8.3 0.7 0.7 14.2 0.5 2.0 0.5 1.4 9.8 9.4 6.8 0.6 5.2 6.2 30.7 1.3 70.3 1.0 0.8 32.3 3.4 4.1 0.9 455.1 149.1 176.4 139.1 13.8 25.2 169.8 186.1 104.5 264.0 197.7 319.1 190.4 212.4 106.7 104.5 196.8 232.7 203.7 169.0 298.8 92.3 78.8 416.3 139.7 219.6 4.2 161.9 102.8 8.7 9.1 166.0 120.0 37.9 144.6 157.1 313.8 187.8 209.7 186.2 272.2 125.3 197.1 174.0 159.3 152.5 475.5 128.2 71.2 72.8 127.5 85.7 284.6 106.3 82.0 120.9 185.1 97.3 98.3 294.1 179.7 136.5 290.0 74.4 138.6 187.3 92.2 565.1 195.8 5.1 0.0 0.4 0.4 0.0 0.2 0.6 1.4 1.7 0.5 0.2 0.3 0.5 0.2 3.6 0.1 1.0 8.1 1.0 0.9 0.9 0.8 1.0 1.1 0.6 0.6 1.0 0.7 0.6 1.3 0.9 1.0 0.0 4.2 0.0 5.9 6.9 1.5 4.3 1.2 0.9 3.0 3.4 0.9 4.3 3.8 0.0 0.0 23.3 3.8 6.4 0.0 1.2 9.3 7.3 6.6 3.9 1.2 90.7 2.9 0.4 68.5 9.2 16.3 8.4 0.0 46.6 8.9 3.0 19.5 1.7 0.9 9.8 10.2 8.0 5.5 13.1 0.9 7.6 0.0 1.0 2.1 0.4 3.1 0.5 0.5 1.8 1.4 0.0 30.8 2.5 0.9 0.0 0.7 0.4 0.0 1.1 15.4 114.5 63.1 31.2 6.1 4.7 8.2 4.2 18.4 2.9 TRAFD1 FLN29 ENSG00000135148 "TRAF-type zinc finger domain containing 1" O14545 12 112125538-112153604 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 117.6;Spermatocytes: 75.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039254, HPA039266" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 3: Monocytes - Immune response regulation" Nucleoplasm Cytosol "HPA039254: AB_10805358, HPA039266: AB_10795142" "unprognostic (7.80e-2)" "prognostic favorable (5.73e-4)" "unprognostic (6.12e-2)" "unprognostic (1.44e-1)" "unprognostic (9.46e-2)" "unprognostic (2.51e-2)" "prognostic unfavorable (4.87e-4)" "unprognostic (1.21e-3)" "unprognostic (1.69e-1)" "unprognostic (1.78e-1)" "unprognostic (3.09e-1)" "unprognostic (2.20e-1)" "prognostic unfavorable (9.26e-6)" "unprognostic (1.07e-1)" "unprognostic (6.15e-2)" "unprognostic (3.33e-3)" "prognostic favorable (3.92e-5)" 17.1 14.6 15.9 30.4 21.5 30.1 20.3 21.2 18.9 21.2 24.7 40.6 16.7 16.8 15.6 32.0 15.4 17.7 22.3 15.1 17.3 15.7 13.5 26.3 37.1 22.4 20.0 18.7 11.8 15.7 11.7 19.0 23.0 22.0 20.6 18.7 19.0 19.8 12.9 35.9 20.3 25.9 20.5 31.3 17.2 29.1 20.1 32.6 13.8 11.4 40.4 29.9 21.7 30.2 23.8 26.2 41.8 40.8 28.8 27.3 22.1 27.2 38.8 36.5 29.4 29.5 21.9 27.4 22.6 28.9 15.7 49.0 42.0 26.3 24.2 47.3 40.1 44.4 37.7 16.3 50.0 27.1 67.7 34.4 43.5 27.1 35.7 37.2 32.6 16.6 50.1 16.9 23.6 41.2 31.5 39.0 35.4 27.8 31.8 43.8 25.6 46.8 24.3 89.5 36.4 27.3 57.4 55.7 15.1 30.8 35.8 38.7 22.1 17.2 12.2 17.1 14.3 40.3 36.2 29.3 18.5 21.6 19.1 323.7 96.1 226.1 45.1 86.8 30.1 56.7 43.1 40.3 50.1 60.2 39.4 36.6 188.2 70.8 93.1 33.5 63.7 101.2 15.9 21.5 21.2 18.9 15.1 17.3 22.4 20.0 23.0 20.5 20.1 30.2 10.7 19.2 13.1 6.8 12.4 12.2 7.4 18.5 30.7 7.0 14.7 11.8 10.9 5.7 18.9 12.9 25.0 20.1 8.5 15.4 5.9 21.3 1.7 9.0 14.3 11.3 15.6 9.0 8.4 20.8 15.6 15.1 15.3 7.5 12.0 10.0 7.9 5.7 14.8 15.2 12.2 10.3 30.5 11.9 9.9 3.7 11.8 14.0 7.2 7.5 117.6 9.9 19.6 10.6 28.6 25.8 15.5 12.8 8.7 22.7 13.0 6.3 10.2 10.9 0.0 5.6 8.8 75.6 36.0 22.0 15.2 26.4 14.0 10.0 9.4 14.4 TRIM7 "GNIP, RNF90" ENSG00000146054 "Tripartite motif containing 7" Q9C029 5 181193924-181205293 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "skeletal muscle: 193.3;tongue: 51.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 17.8;Cardiomyocytes: 40.1;Squamous epithelial cells: 39.6;Suprabasal keratinocytes: 28.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HaCaT: 16.4;HDLM-2: 35.0;PC-3: 18.8;TIME: 16.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA039213 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 37: Myocytes - Muscle contraction" Vesicles "Nucleoplasm, Cytosol" "HPA039213: AB_10795173" "unprognostic (6.58e-2)" "unprognostic (1.17e-1)" "unprognostic (5.20e-2)" "unprognostic (1.10e-2)" "unprognostic (6.85e-2)" "unprognostic (1.80e-2)" "unprognostic (3.89e-4)" "unprognostic (3.45e-2)" "unprognostic (3.72e-1)" "unprognostic (1.64e-1)" "unprognostic (3.48e-2)" "unprognostic (1.97e-1)" "unprognostic (7.16e-3)" "unprognostic (1.26e-1)" "unprognostic (3.90e-2)" "unprognostic (6.17e-2)" "unprognostic (1.15e-2)" 2.1 1.5 1.2 0.4 1.0 0.4 2.1 10.5 3.0 5.5 0.4 1.9 0.3 1.3 3.1 27.0 2.2 0.2 8.5 0.9 1.7 3.9 0.6 2.6 0.4 3.1 2.9 1.5 4.8 2.7 5.5 0.3 2.8 2.8 0.5 1.6 7.3 0.6 193.3 28.7 1.3 0.6 1.3 1.4 2.2 1.3 2.0 0.4 6.3 51.0 2.1 2.2 9.5 1.3 9.0 4.4 0.1 0.5 0.7 0.8 0.2 1.9 0.0 0.7 1.8 0.4 12.0 0.6 6.1 2.6 3.7 16.4 4.8 13.8 0.2 35.0 1.8 0.9 12.2 0.2 2.2 0.0 2.0 0.1 10.5 0.4 6.7 2.7 3.9 1.6 0.5 2.0 0.4 1.3 0.5 0.3 0.0 14.5 18.8 0.4 6.0 1.4 4.9 0.0 0.4 1.1 4.2 0.2 6.5 0.2 1.0 0.4 16.0 0.2 3.4 0.6 6.3 2.8 0.4 1.0 0.5 0.7 1.5 0.0 1.7 0.0 0.4 0.7 0.7 0.1 0.4 0.4 0.3 0.2 0.7 0.5 0.0 0.1 0.5 0.2 0.9 0.3 1.2 1.0 10.5 3.0 0.9 1.7 3.1 2.9 2.8 1.3 2.0 1.3 7.3 0.0 1.1 0.0 1.0 17.8 4.3 11.1 12.0 6.2 0.8 1.5 40.1 0.0 6.3 3.7 0.0 0.1 0.8 5.9 5.9 0.7 0.9 0.2 0.3 4.6 0.0 0.0 1.3 2.4 0.7 4.8 11.2 0.7 0.0 0.1 5.7 0.4 1.1 0.0 3.9 3.3 2.0 6.0 2.8 0.0 0.9 2.9 1.8 0.0 5.7 0.6 1.0 2.0 0.1 5.0 6.5 1.5 0.1 2.5 0.0 1.5 2.9 2.9 13.1 17.3 5.8 1.5 0.4 39.6 28.4 0.0 1.4 0.1 3.4 5.3 TRIP13 16E1BP ENSG00000071539 "Thyroid hormone receptor interactor 13" Q15645 5 892884-919357 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Meiosis, Oogenesis, Spermatogenesis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 29.9" "Cell type enhanced" "Detected in many" "Early spermatids: 115.4;Late spermatids: 206.9;Respiratory ciliated cells: 79.9;Spermatocytes: 86.4;Spermatogonia: 70.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA005727, HPA053093" Enhanced Approved Nucleoplasm NA NA 78000 "Cluster 40: NK-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "HPA005727: AB_10603220, HPA053093: AB_2682042" "unprognostic (1.65e-2)" "unprognostic (1.65e-1)" "unprognostic (8.59e-2)" "prognostic unfavorable (3.93e-4)" "unprognostic (2.34e-2)" "unprognostic (3.96e-2)" "prognostic unfavorable (1.30e-6)" "unprognostic (4.44e-3)" "unprognostic (1.73e-3)" "prognostic favorable (1.39e-4)" "unprognostic (4.25e-2)" "unprognostic (2.24e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (5.04e-2)" "unprognostic (1.99e-1)" "unprognostic (1.31e-1)" "unprognostic (3.34e-1)" 1.4 0.7 2.0 4.4 2.1 6.0 2.7 0.9 1.8 1.5 1.0 3.8 3.5 1.8 0.6 4.6 6.7 0.7 0.4 1.6 1.5 1.1 0.8 1.3 7.1 1.3 2.0 2.0 1.3 0.2 1.6 3.3 1.4 0.8 5.7 0.5 1.0 0.4 0.6 2.3 3.6 3.5 1.1 1.9 1.7 29.9 1.9 9.3 0.5 0.3 8.4 1.9 1.7 1.2 67.5 73.9 46.6 69.6 4.3 10.1 51.8 68.6 33.1 103.4 96.7 72.2 43.4 59.1 48.7 39.5 90.1 48.7 100.3 47.6 129.1 91.0 83.7 40.6 136.4 52.3 1.1 67.3 23.9 4.7 3.6 87.0 37.3 10.7 51.5 45.9 61.7 50.2 71.7 45.7 67.6 60.6 53.0 37.7 69.4 38.8 87.3 113.0 29.3 34.2 47.9 49.0 103.1 38.2 20.8 40.2 71.3 32.0 26.4 55.6 70.4 46.5 79.0 31.9 68.9 64.6 34.2 79.3 63.1 0.0 0.0 0.0 0.4 0.0 0.2 1.1 0.6 0.7 0.1 1.2 0.2 0.1 0.0 1.6 0.1 1.0 2.1 0.4 2.0 2.1 0.9 1.8 1.6 1.5 1.3 2.0 1.4 1.1 1.9 1.2 0.7 0.0 1.1 0.3 4.3 3.4 3.5 7.3 4.0 0.9 2.2 1.8 0.3 0.0 5.0 0.0 0.0 8.6 0.7 2.2 0.0 3.0 115.4 29.3 2.1 2.5 4.2 14.3 1.3 2.0 25.2 3.4 1.5 3.8 5.7 9.8 2.2 0.4 7.3 3.3 0.5 3.0 4.1 1.3 4.2 206.9 2.1 1.7 0.0 0.0 1.1 0.7 0.0 0.0 0.4 2.2 1.8 2.2 18.1 2.8 0.5 1.2 79.9 0.9 6.6 2.5 5.2 86.4 70.1 7.6 1.4 3.4 3.2 2.7 5.1 3.3 TRPM1 "CSNB1C, LTRPC1, MLSN1" ENSG00000134160 "Transient receptor potential cation channel subfamily M member 1" Q7Z4N2 15 31001061-31161273 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sensory transduction, Transport, Vision" "Ion channel, Ligand-gated ion channel, Receptor" "Congenital stationary night blindness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "retina: 9.4;skin 1: 4.1" "Group enriched" "Detected in some" 7 "Bipolar cells: 627.4;Melanocytes: 158.3" "Cancer enriched" "Detected in single" 179 "melanoma: 14.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 112 "SK-MEL-30: 12.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA014779, HPA071139" Enhanced Uncertain "Golgi apparatus,Plasma membrane,Centriolar satellite" NA NA "Cluster 77: Retina - Visual perception" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 56: Bipolar cells - Visual perception" "Centriolar satellite" "Golgi apparatus, Plasma membrane" "HPA014779: AB_2669090, HPA071139: " "unprognostic (5.28e-2)" "unprognostic (1.35e-1)" "unprognostic (9.89e-2)" "unprognostic (3.07e-1)" "unprognostic (1.97e-1)" "unprognostic (1.70e-1)" "unprognostic (1.29e-3)" "unprognostic (2.83e-1)" "unprognostic (2.89e-2)" "unprognostic (1.67e-1)" "unprognostic (1.45e-2)" "unprognostic (2.58e-1)" "unprognostic (7.84e-2)" "unprognostic (6.20e-4)" "unprognostic (1.48e-1)" "unprognostic (2.63e-2)" 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 9.4 0.1 0.0 0.0 4.1 0.0 0.0 0.5 0.0 0.0 1.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.3 0.1 0.2 0.2 0.4 0.3 0.5 0.3 0.5 0.0 0.0 0.0 0.7 0.0 4.2 0.0 0.0 0.0 627.4 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 50.5 0.1 0.1 1.7 0.0 0.0 0.9 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 13.5 0.8 0.0 0.0 0.0 1.0 6.3 0.0 0.0 158.3 0.0 0.0 11.0 0.0 0.0 19.4 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 22.2 0.0 0.1 0.1 10.1 4.4 1.8 1.0 1.0 0.0 0.0 0.0 0.1 TRPM4 FLJ20041 ENSG00000130529 "Transient receptor potential cation channel subfamily M member 4" Q8TD43 19 49157741-49211836 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Adaptive immunity, Immunity, Ion transport, Transport" "Calmodulin-binding, Ion channel" "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 179.2;Hepatocytes: 81.7;Intestinal goblet cells: 114.8;Paneth cells: 77.1;Undifferentiated cells: 88.9" "Cancer enriched" "Detected in all" 4 "prostate cancer: 85.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "dendritic cells: 3.3;granulocytes: 2.8;monocytes: 4.3" "Cell line enhanced" "Detected in many" "OE19: 32.7;RT4: 60.8;SK-BR-3: 38.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA041169 Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Plasma membrane" "HPA041169: AB_2677343" "unprognostic (8.20e-3)" "unprognostic (1.41e-1)" "unprognostic (7.86e-2)" "prognostic favorable (2.88e-7)" "unprognostic (1.62e-2)" "unprognostic (9.78e-2)" "unprognostic (1.77e-2)" "unprognostic (2.90e-1)" "unprognostic (3.33e-2)" "unprognostic (3.38e-2)" "unprognostic (2.94e-2)" "unprognostic (2.79e-1)" "prognostic favorable (2.53e-7)" "unprognostic (8.46e-3)" "unprognostic (2.16e-1)" "unprognostic (5.70e-2)" "unprognostic (1.00e-2)" 10.8 6.1 5.8 6.1 5.4 4.6 13.5 8.5 7.0 11.5 4.8 46.1 25.3 9.9 2.5 13.1 9.2 7.4 23.0 5.9 4.5 22.8 15.4 16.0 1.8 6.2 7.4 3.3 10.1 3.7 5.6 5.3 6.9 35.7 12.9 1.3 27.3 6.2 14.0 26.6 22.9 3.4 4.2 5.5 20.6 5.4 6.6 1.0 17.3 5.3 1.9 13.7 14.4 5.1 11.9 9.0 2.1 9.5 7.7 6.6 6.6 10.0 6.0 2.7 3.7 6.1 18.7 0.4 2.7 6.8 3.6 15.7 1.3 3.0 1.0 0.2 3.4 1.9 4.0 3.7 6.6 0.3 11.7 9.3 13.6 5.3 2.6 3.3 4.6 1.0 4.9 2.1 6.9 17.4 0.8 0.9 1.0 32.7 13.3 4.1 2.0 0.6 4.6 60.8 0.8 2.2 4.1 38.6 2.2 0.7 22.6 3.7 11.8 14.4 7.8 7.9 0.2 3.9 4.3 0.4 7.9 7.4 5.3 2.2 4.3 0.7 0.3 2.5 0.2 0.5 0.2 0.2 3.3 0.5 0.3 0.3 2.8 0.5 1.0 3.1 0.2 1.4 5.8 5.4 8.5 7.0 5.9 4.5 6.2 7.4 6.9 4.2 6.6 5.1 12.8 32.1 2.6 9.8 3.5 12.5 15.3 9.9 9.1 2.0 19.0 14.6 16.7 17.2 12.3 14.7 0.0 6.6 0.2 179.2 19.6 7.9 2.9 17.5 8.2 11.7 21.7 0.0 5.4 18.5 6.8 6.0 71.4 36.2 5.7 2.9 11.4 81.7 19.9 0.0 8.5 114.8 14.2 9.8 19.0 3.1 6.8 8.5 39.2 9.4 12.8 6.7 0.0 3.5 0.9 32.9 77.1 7.2 7.6 35.5 55.3 3.8 8.9 2.6 32.9 2.2 8.5 6.1 15.7 8.4 11.5 3.4 1.9 4.1 88.9 33.1 TST RDS ENSG00000128311 "Thiosulfate sulfurtransferase" Q16762 22 37010859-37020183 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 561.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 565.8;Hepatocytes: 414.9;Paneth cells: 463.4;Proximal enterocytes: 278.5;Proximal tubular cells: 254.5;Undifferentiated cells: 217.4" "Cancer enhanced" "Detected in all" "liver cancer: 177.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 25.0" "Group enriched" "Detected in all" 6 "dendritic cells: 25.0;granulocytes: 21.8;monocytes: 17.7" "Cell line enhanced" "Detected in many" "OE19: 264.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003044, HPA003643, CAB009546" Enhanced Supported Mitochondria NA NA 560000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "CAB009546: AB_2211220, HPA003044: AB_1858417, HPA003643: AB_1080411" "unprognostic (3.09e-2)" "unprognostic (2.70e-1)" "unprognostic (2.07e-1)" "unprognostic (1.21e-2)" "unprognostic (2.36e-2)" "unprognostic (1.11e-1)" "unprognostic (2.49e-2)" "unprognostic (2.38e-2)" "unprognostic (2.32e-1)" "unprognostic (7.96e-3)" "unprognostic (4.38e-2)" "unprognostic (1.78e-1)" "prognostic favorable (7.59e-6)" "unprognostic (6.08e-3)" "unprognostic (3.46e-1)" "unprognostic (1.16e-1)" "prognostic favorable (1.04e-4)" 51.4 154.1 31.3 20.9 40.5 27.1 37.3 38.2 36.0 34.1 31.3 190.7 147.7 18.9 2.9 96.7 25.7 75.9 69.9 29.1 33.1 100.8 561.2 22.7 8.1 34.4 35.2 26.9 63.6 9.4 12.4 7.9 34.4 26.4 80.3 1.3 39.8 18.2 52.9 33.8 114.2 13.2 35.4 16.9 88.4 8.1 35.8 4.3 17.1 34.9 16.2 30.0 56.7 39.0 42.6 86.1 10.8 36.8 25.9 10.6 21.4 23.0 18.6 12.6 18.3 25.4 25.7 11.1 18.8 17.0 11.9 35.1 7.9 22.3 2.7 33.6 50.0 11.5 15.5 49.7 64.9 16.4 26.4 20.1 23.9 9.1 7.6 17.5 31.1 5.9 14.2 18.2 6.0 90.8 0.5 49.9 18.7 264.4 39.3 37.0 11.7 19.7 35.9 36.7 6.4 17.1 24.2 41.4 31.7 10.2 43.4 39.3 25.1 14.0 27.2 24.2 7.4 14.0 15.4 3.4 5.3 46.4 8.5 10.9 17.7 8.0 0.8 4.7 1.7 2.8 0.8 0.6 25.0 1.7 0.4 0.2 21.8 3.7 1.5 1.7 2.1 8.1 31.3 40.5 38.2 36.0 29.1 33.1 34.4 35.2 34.4 35.4 35.8 39.0 13.9 28.9 74.8 10.1 7.8 1.3 9.5 20.4 12.0 1.3 32.7 16.6 39.2 170.1 23.7 20.2 0.0 11.6 2.5 565.8 46.9 45.3 1.9 53.3 30.2 13.4 34.3 35.3 0.3 44.0 6.4 14.6 126.9 74.3 14.0 60.9 39.3 414.9 15.1 1.7 0.5 162.8 8.2 28.9 6.8 3.5 13.1 23.2 1.8 1.0 18.6 27.3 3.1 3.5 7.4 36.8 463.4 7.9 24.5 10.5 278.5 254.5 19.2 0.8 0.0 10.7 11.5 2.4 0.5 39.8 2.4 11.4 5.0 57.5 217.4 17.3 TTC22 FLJ20619 ENSG00000006555 "Tetratricopeptide repeat domain 22" Q5TAA0 1 54779712-54801323 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 109.6;vagina: 48.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 72.4;Gastric mucus-secreting cells: 23.0;Intestinal goblet cells: 27.1;Paneth cells: 36.9;Proximal enterocytes: 51.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "A-431: 9.0;CAPAN-2: 10.7;HaCaT: 12.3;hTCEpi: 6.9;OE19: 14.7;RPMI-8226: 8.1" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA035072 Uncertain NA NA "Cluster 35: T-regs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA035072: AB_10602252" "prognostic favorable (2.06e-4)" "unprognostic (8.52e-2)" "unprognostic (4.84e-2)" "unprognostic (4.98e-2)" "unprognostic (1.01e-2)" "unprognostic (1.10e-2)" "prognostic unfavorable (7.73e-4)" "unprognostic (2.02e-1)" "unprognostic (2.60e-1)" "unprognostic (3.07e-2)" "unprognostic (4.57e-2)" "unprognostic (7.27e-2)" "unprognostic (1.51e-3)" "unprognostic (5.08e-3)" "unprognostic (1.00e-1)" "unprognostic (3.16e-2)" "unprognostic (2.21e-1)" 0.4 0.9 1.0 2.4 3.2 1.4 2.6 0.7 1.9 21.7 2.6 14.5 15.7 1.5 2.7 109.6 3.4 2.7 0.2 1.0 2.4 9.3 6.1 2.1 1.6 0.7 0.7 0.4 9.4 16.5 6.1 0.2 0.7 6.3 11.2 0.2 17.5 1.7 0.6 25.0 17.4 0.7 0.5 2.0 13.1 0.7 2.2 2.3 4.1 0.0 7.2 3.7 48.1 0.7 9.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 2.9 10.7 0.1 0.4 0.0 0.0 12.3 0.0 3.6 0.0 4.0 0.1 0.1 0.2 0.1 0.0 0.1 0.2 0.0 6.9 0.0 0.0 0.0 0.0 0.0 0.1 3.3 0.0 0.0 0.0 0.1 0.1 14.7 1.1 0.1 0.1 8.1 0.5 2.2 0.3 0.2 0.7 0.1 0.0 0.2 0.4 0.2 0.1 0.1 0.0 0.2 0.1 0.8 2.2 0.1 0.1 0.1 0.0 1.0 0.0 2.5 3.4 0.0 2.0 0.7 1.6 3.7 0.0 0.5 1.4 1.7 1.3 1.6 0.0 0.0 2.7 0.5 1.0 3.2 0.7 1.9 1.0 2.4 0.7 0.7 0.7 0.5 2.2 0.7 0.0 0.0 3.1 0.0 1.8 1.3 5.9 3.2 3.4 0.0 3.9 3.6 2.7 15.7 4.5 3.7 0.0 0.3 5.9 72.4 7.9 5.0 2.7 3.3 0.4 0.3 2.4 2.7 0.3 9.1 0.4 0.5 23.0 3.2 0.0 0.0 0.4 2.2 0.0 0.0 0.1 27.1 4.1 0.0 0.3 1.1 0.3 0.4 1.8 0.0 0.0 0.0 7.2 0.0 0.1 10.5 36.9 0.0 1.0 6.0 51.7 8.9 5.7 0.0 0.0 0.0 0.4 0.4 0.9 19.7 4.5 0.0 4.1 0.1 15.4 13.9 TTC39A "C1orf34, DEME-6, KIAA0452" ENSG00000085831 "Tetratricopeptide repeat domain 39A" Q5SRH9 1 51287258-51345116 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 59.5" "Group enriched" "Detected in many" 9 "Early spermatids: 425.0;Late spermatids: 616.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 42 "plasmacytoid DC: 31.7" "Lineage enriched" "Detected in single" 42 "dendritic cells: 31.7" "Cell line enhanced" "Detected in many" "HDLM-2: 70.6;MCF7: 52.4;SK-BR-3: 153.7;T-47d: 111.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA028098, HPA043440" Uncertain Enhanced Centrosome NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 34: Spermatids - Unknown function" Centrosome "HPA028098: AB_10601705, HPA043440: AB_2678483" "unprognostic (5.05e-2)" "unprognostic (1.95e-1)" "unprognostic (3.35e-2)" "unprognostic (7.60e-2)" "unprognostic (8.53e-3)" "unprognostic (2.86e-2)" "prognostic unfavorable (5.05e-5)" "unprognostic (1.46e-1)" "unprognostic (2.58e-1)" "unprognostic (8.47e-2)" "unprognostic (1.51e-1)" "unprognostic (1.38e-1)" "unprognostic (7.89e-2)" "unprognostic (1.73e-3)" "unprognostic (5.40e-2)" "unprognostic (5.96e-2)" "unprognostic (1.06e-1)" 2.2 8.2 3.5 3.3 3.5 1.7 35.9 3.0 9.6 14.1 0.0 29.5 6.1 1.0 15.9 18.4 7.5 14.9 15.3 1.0 11.4 26.6 2.8 9.1 1.4 7.4 5.3 0.3 13.5 13.5 11.0 0.3 14.0 20.5 35.2 4.6 11.5 4.2 4.1 10.5 8.1 1.6 2.2 0.3 29.4 59.5 7.7 0.5 10.1 1.7 2.0 8.0 9.4 3.7 6.4 3.4 0.7 0.3 0.4 0.7 28.2 0.3 0.2 0.2 0.2 18.2 2.8 0.1 9.6 0.4 0.4 0.2 3.8 0.2 0.1 70.6 9.7 0.5 1.8 3.2 1.1 0.0 0.7 0.1 1.6 0.1 0.0 0.8 1.4 0.2 0.4 0.1 0.2 52.4 0.6 0.2 4.8 33.8 0.6 0.1 0.2 4.3 28.6 9.1 22.1 1.6 0.5 153.7 1.8 2.0 111.7 0.8 0.8 0.4 2.5 0.5 0.5 5.4 7.1 0.2 2.1 0.4 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.7 0.0 0.0 31.7 0.0 0.3 3.5 3.5 3.0 9.6 1.0 11.4 7.4 5.3 14.0 2.2 7.7 3.7 0.4 3.2 25.2 1.3 1.1 1.5 5.3 1.7 0.0 2.5 30.8 15.1 13.0 5.7 6.4 9.2 0.0 0.5 15.3 29.3 11.7 38.9 425.0 5.4 3.0 1.9 41.4 9.7 9.7 52.7 4.8 0.9 21.9 9.5 3.8 0.5 0.4 0.6 2.0 0.0 10.2 56.0 6.1 0.3 1.3 616.8 2.5 0.9 0.0 1.0 2.6 1.7 0.0 0.0 0.9 30.5 13.7 2.6 0.4 12.0 2.7 24.4 9.3 7.3 6.6 1.8 1.3 22.8 6.5 4.8 6.5 3.4 1.7 0.5 20.7 14.6 TUT7 "FLJ13409, KIAA1711, PAPD6, TENT3B, ZCCHC6" ENSG00000083223 "Terminal uridylyl transferase 7" Q5VYS8 9 86287733-86354454 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 80.3;Endometrial stromal cells: 61.1;Glandular and luminal cells: 206.7;Syncytiotrophoblasts: 92.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 114.6" "Group enriched" "Detected in all" 5 "granulocytes: 114.6;monocytes: 47.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020615, HPA020620" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 85: Liver - Metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Cytosol Nucleoplasm "HPA020615: AB_1858983, HPA020620: AB_1858984" "unprognostic (1.10e-1)" "unprognostic (1.36e-1)" "unprognostic (1.64e-1)" "unprognostic (1.26e-2)" "unprognostic (3.66e-1)" "unprognostic (1.39e-1)" "unprognostic (4.11e-2)" "unprognostic (2.49e-2)" "unprognostic (4.43e-2)" "unprognostic (6.51e-2)" "unprognostic (1.91e-2)" "unprognostic (3.07e-1)" "unprognostic (5.79e-3)" "unprognostic (1.59e-2)" "unprognostic (1.13e-1)" "unprognostic (4.14e-2)" "unprognostic (1.40e-1)" 12.5 9.4 4.8 16.0 6.4 22.6 18.7 5.9 10.0 12.8 10.9 12.1 11.0 9.1 8.9 24.7 8.8 11.3 8.2 5.1 7.9 7.5 38.4 16.5 19.1 9.0 6.3 8.7 13.1 8.7 8.2 14.3 7.8 20.8 11.8 7.7 14.2 7.2 13.6 33.7 12.3 7.8 5.1 20.6 13.6 11.6 9.2 15.1 8.6 9.3 19.2 13.4 16.0 9.0 16.2 17.2 9.8 14.3 22.4 36.0 12.2 21.6 20.5 9.1 10.6 7.8 13.7 22.8 18.9 14.0 9.5 27.3 11.8 12.0 13.5 27.1 6.0 16.5 18.4 13.7 19.3 19.1 21.8 23.5 22.7 14.5 16.2 13.7 15.0 12.3 15.9 24.0 24.6 14.9 16.0 11.0 7.5 25.1 11.1 8.0 17.5 10.1 15.3 31.4 7.2 5.7 13.1 15.5 7.4 11.6 6.4 7.8 24.8 8.7 10.5 15.7 14.8 27.4 23.3 16.5 20.7 10.8 11.8 35.4 19.4 20.5 15.0 24.7 12.5 11.6 8.2 10.7 11.9 12.2 9.5 10.1 114.6 12.8 47.8 5.5 8.8 8.9 4.8 6.4 5.9 10.0 5.1 7.9 9.0 6.3 7.8 5.1 9.2 9.0 28.1 0.0 0.0 0.0 14.5 0.0 0.0 0.0 0.0 0.0 34.2 16.4 0.0 0.0 0.0 9.2 0.0 22.4 36.6 0.0 5.9 29.6 0.0 80.3 61.1 7.2 0.0 0.0 0.0 17.9 17.4 5.6 0.0 206.7 0.0 36.0 0.0 0.0 22.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.1 0.0 0.0 12.4 0.0 0.0 0.0 0.0 27.8 0.0 0.0 13.8 0.0 0.0 6.7 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 0.0 92.5 14.8 30.9 0.0 0.0 TYSND1 "MGC34695, NET41" ENSG00000156521 "Trypsin like peroxisomal matrix peptidase 1" Q2T9J0 10 70137981-70146700 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Early spermatids: 120.7;Late spermatids: 227.4;Spermatocytes: 124.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HaCaT: 27.5;PC-3: 41.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030304 Approved Uncertain Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Centrosome" Cytosol "HPA030304: AB_10670560" "unprognostic (4.75e-3)" "unprognostic (4.30e-2)" "unprognostic (2.44e-2)" "unprognostic (7.69e-2)" "unprognostic (1.84e-1)" "unprognostic (4.53e-2)" "unprognostic (2.02e-2)" "unprognostic (1.55e-1)" "unprognostic (1.33e-1)" "unprognostic (1.10e-1)" "unprognostic (1.59e-2)" "unprognostic (2.80e-1)" "unprognostic (1.37e-1)" "unprognostic (9.26e-3)" "unprognostic (1.91e-1)" "unprognostic (1.30e-1)" "unprognostic (1.69e-2)" 5.7 6.0 1.4 1.9 1.3 0.9 5.4 1.7 1.8 5.8 1.1 4.9 3.3 4.1 0.6 11.8 4.5 0.6 2.9 1.0 0.9 5.2 6.4 2.8 1.8 2.1 0.7 4.2 6.2 1.3 3.4 1.3 0.8 5.7 0.6 0.2 5.7 1.5 3.2 11.4 5.0 0.3 0.6 5.4 3.9 14.2 0.9 1.2 4.6 0.5 0.9 4.8 6.5 1.4 16.0 10.2 0.8 6.2 1.0 0.9 3.7 2.2 1.4 2.0 1.8 6.2 9.6 13.8 6.0 0.5 0.6 27.5 1.0 3.9 0.4 8.9 9.5 0.7 2.9 3.3 2.4 1.2 0.1 2.0 7.6 1.7 3.1 1.2 1.4 4.9 0.1 4.3 0.8 6.3 5.3 5.6 3.3 3.5 41.7 8.9 2.6 6.2 0.9 2.6 7.4 3.8 6.7 14.8 6.1 0.2 9.4 1.1 2.6 2.5 1.7 4.8 8.7 14.9 9.9 7.0 2.9 6.2 1.8 0.0 0.8 0.7 3.8 1.2 2.4 3.0 2.2 2.8 0.9 3.3 3.0 2.6 0.3 2.0 0.7 0.7 2.6 1.4 1.4 1.3 1.7 1.8 1.0 0.9 2.1 0.7 0.8 0.6 0.9 1.4 6.1 9.6 5.3 4.9 12.6 14.3 14.5 13.3 14.8 6.9 14.8 16.9 4.2 27.1 7.8 11.0 0.0 35.2 15.5 14.6 17.6 7.8 120.7 5.5 6.8 6.3 14.3 5.0 6.7 9.5 9.8 7.5 5.1 6.3 13.4 9.3 6.8 16.5 12.1 0.0 6.0 12.1 16.2 10.7 6.6 227.4 9.3 8.2 12.4 6.5 6.1 7.0 12.3 11.6 5.5 5.5 11.6 7.9 7.5 14.5 19.2 16.5 3.9 4.4 6.6 6.9 6.1 124.7 12.5 22.4 18.5 16.7 14.0 10.6 21.0 8.8 UBAC1 "GBDR1, KPC2, UBADC1" ENSG00000130560 "UBA domain containing 1" Q9BSL1 9 135932969-135961373 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 301.3;tongue: 171.0" "Cell type enhanced" "Detected in all" "Erythroid cells: 290.9;Late spermatids: 197.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 246.4;K-562: 316.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005651 Approved Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA 87000 "Cluster 14: Monocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 6: Erythroid cells - Oxygen transport" "Plasma membrane, Cytosol" "Golgi apparatus" "HPA005651: AB_1858489" "unprognostic (8.41e-2)" "prognostic favorable (4.34e-6)" "unprognostic (2.10e-1)" "unprognostic (9.15e-2)" "unprognostic (4.11e-1)" "unprognostic (3.85e-2)" "unprognostic (7.68e-3)" "unprognostic (2.85e-1)" "unprognostic (4.37e-2)" "unprognostic (3.23e-1)" "unprognostic (3.92e-3)" "unprognostic (1.20e-1)" "prognostic favorable (3.58e-7)" "unprognostic (1.95e-3)" "unprognostic (9.46e-2)" "unprognostic (3.16e-2)" "unprognostic (5.78e-2)" 23.1 20.7 42.2 14.7 44.8 82.5 20.7 43.0 43.0 23.8 41.4 38.6 24.3 22.0 12.9 37.4 22.8 12.0 72.0 40.4 42.2 23.5 24.9 19.8 15.7 43.2 42.7 20.9 17.1 27.1 23.5 22.8 41.8 24.7 18.4 15.2 27.8 20.6 301.3 53.2 23.3 16.3 43.7 21.0 23.0 43.1 44.0 17.7 18.0 171.0 16.5 28.3 27.0 41.0 37.4 42.7 29.7 43.4 22.0 25.6 55.7 32.0 27.1 38.9 31.2 59.7 46.3 44.8 30.1 26.4 46.1 124.4 41.9 37.0 17.5 246.4 39.6 37.4 79.0 33.8 22.9 49.2 34.4 24.2 47.7 24.6 23.8 26.0 32.8 41.4 316.6 35.5 31.2 76.9 40.4 50.5 70.5 87.4 71.8 45.1 55.8 59.3 28.0 23.7 46.0 50.6 46.3 41.4 33.5 26.3 34.9 52.5 26.8 22.0 33.0 26.5 40.2 20.5 41.1 53.9 40.7 43.9 30.6 6.5 17.6 8.7 4.8 28.4 5.1 4.9 5.4 3.2 15.6 2.8 2.8 3.3 3.7 4.0 33.4 1.6 4.5 7.0 42.2 44.8 43.0 43.0 40.4 42.2 43.2 42.7 41.8 43.7 44.0 41.0 42.8 16.0 10.0 18.6 14.5 40.7 38.8 41.8 43.3 38.3 29.6 36.2 85.7 11.5 24.5 27.6 31.3 148.6 20.7 45.5 93.9 16.3 101.6 82.9 33.7 27.5 16.8 290.9 17.3 22.9 32.7 22.5 21.9 21.3 7.0 28.6 20.3 32.7 75.2 13.5 23.6 37.4 28.5 34.3 30.3 197.4 19.6 41.8 35.6 9.4 46.0 60.7 13.4 9.0 14.1 22.6 42.3 22.6 24.6 23.1 47.9 35.6 96.0 44.1 19.7 42.8 27.4 57.7 54.9 73.2 64.8 60.5 16.5 25.7 55.6 39.4 UBE2G1 "UBC7, UBE2G" ENSG00000132388 "Ubiquitin conjugating enzyme E2 G1" P62253 17 4269259-4366628 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 210.2" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 286.0;Late spermatids: 248.3;Suprabasal keratinocytes: 239.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045681, HPA050551" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 13: T-cells - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 28: Keratinocytes - Keratinization" "Nucleoplasm, Cytosol" "HPA045681: AB_2679417, HPA050551: AB_2681171" "unprognostic (1.57e-3)" "unprognostic (1.94e-1)" "unprognostic (2.34e-2)" "unprognostic (1.80e-2)" "unprognostic (5.16e-2)" "unprognostic (5.84e-2)" "unprognostic (1.87e-1)" "unprognostic (2.64e-2)" "unprognostic (5.13e-2)" "unprognostic (1.86e-1)" "unprognostic (2.80e-1)" "unprognostic (1.67e-2)" "unprognostic (9.99e-2)" "unprognostic (2.16e-1)" "unprognostic (4.58e-2)" "unprognostic (3.97e-2)" "unprognostic (6.50e-2)" 21.0 19.1 15.8 25.4 21.4 31.5 20.1 21.0 24.3 25.2 11.6 39.7 22.5 22.7 14.7 52.2 16.3 16.0 37.9 16.1 18.7 27.0 30.3 15.6 38.8 21.5 19.2 15.6 18.4 21.5 9.7 18.9 21.7 22.6 24.2 17.5 21.0 20.8 210.2 28.0 23.6 27.2 20.3 20.7 21.8 23.2 21.0 24.9 16.1 84.1 46.4 24.5 32.1 26.5 54.5 57.8 52.7 38.9 42.2 44.3 74.9 51.7 41.4 48.2 42.1 40.0 27.0 84.5 52.8 51.2 39.4 57.2 66.3 48.1 77.2 44.8 53.9 31.7 28.6 45.9 41.3 46.5 57.4 38.0 70.3 45.8 66.1 33.8 65.6 55.8 56.5 88.9 40.1 24.3 59.4 42.5 58.2 40.1 29.6 76.1 27.9 78.1 56.4 35.1 22.7 42.3 48.9 41.8 41.6 77.4 41.1 29.9 49.6 48.1 36.8 57.0 58.7 34.3 43.8 118.9 36.9 42.8 37.7 13.3 15.8 39.0 22.2 16.8 29.9 34.1 28.3 29.1 20.2 24.4 28.3 28.9 28.1 32.5 18.6 14.8 28.9 21.8 15.8 21.4 21.0 24.3 16.1 18.7 21.5 19.2 21.7 20.3 21.0 26.5 28.3 22.4 14.4 31.3 70.6 286.0 36.5 47.8 111.5 18.8 47.0 31.0 67.6 27.1 32.2 25.8 6.2 47.0 47.8 41.4 82.2 30.9 139.5 36.7 25.7 35.5 38.4 26.5 47.9 26.7 59.6 31.1 32.6 39.9 21.0 13.9 31.1 62.3 48.1 15.2 46.3 38.3 44.7 36.5 81.1 248.3 19.6 35.7 67.6 30.9 43.1 28.7 36.0 36.2 84.4 43.0 30.4 21.1 154.3 65.7 40.4 75.6 35.4 17.1 6.6 25.9 43.5 70.8 50.8 85.3 239.7 66.8 58.2 13.8 30.1 54.0 UBIAD1 "SCCD, TERE1" ENSG00000120942 "UbiA prenyltransferase domain containing 1" Q9Y5Z9 1 11273198-11296049 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Menaquinone biosynthesis, Ubiquinone biosynthesis" "Prenyltransferase, Transferase" "Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044862 Approved Vesicles NA NA "Cluster 30: Non-specific - Translation" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "HPA044862: AB_2679117" "unprognostic (1.79e-2)" "unprognostic (2.26e-1)" "unprognostic (5.06e-2)" "unprognostic (1.74e-1)" "unprognostic (7.95e-3)" "unprognostic (7.55e-2)" "unprognostic (1.16e-2)" "unprognostic (2.01e-1)" "unprognostic (1.61e-1)" "unprognostic (2.55e-1)" "unprognostic (1.20e-1)" "unprognostic (1.63e-1)" "prognostic favorable (6.80e-5)" "unprognostic (3.00e-1)" "unprognostic (3.89e-1)" "unprognostic (2.03e-2)" "unprognostic (1.25e-1)" 7.3 7.5 5.5 7.6 7.5 7.6 8.3 6.9 7.0 6.8 2.3 7.0 5.5 8.4 6.1 5.9 9.6 4.6 8.2 5.2 6.1 6.5 10.1 6.1 10.2 7.5 7.5 11.5 10.8 10.0 5.8 6.4 6.8 7.1 6.8 8.0 7.0 6.6 17.7 8.1 6.4 7.9 6.6 7.1 7.2 9.2 7.1 11.9 7.7 13.8 10.5 8.1 5.6 10.1 14.5 14.1 11.0 21.3 8.0 7.4 14.8 15.6 12.7 16.4 14.9 16.4 13.1 28.5 15.6 11.1 15.4 19.5 28.1 18.7 19.9 20.0 24.1 19.1 14.5 22.0 14.5 29.5 15.9 11.2 24.9 22.2 26.3 8.7 12.2 25.8 23.1 22.9 11.2 14.8 19.1 14.7 13.3 27.1 20.7 18.0 24.6 34.6 12.7 9.5 13.6 14.5 16.6 16.3 21.5 4.5 12.1 15.3 10.2 14.4 15.5 15.1 20.5 18.6 27.9 52.4 9.2 38.3 18.3 11.5 12.8 19.5 24.3 17.5 27.3 45.3 32.5 24.8 16.9 42.1 48.5 33.3 3.9 20.5 15.6 21.1 33.8 22.2 5.5 7.5 6.9 7.0 5.2 6.1 7.5 7.5 6.8 6.6 7.1 10.1 9.4 9.6 14.6 4.2 19.6 15.4 16.7 11.2 22.2 11.9 13.3 13.7 8.3 11.5 18.1 5.5 8.4 10.6 17.5 7.4 11.7 10.8 34.1 6.3 9.6 9.5 4.9 13.3 4.2 13.3 14.7 11.4 13.3 9.6 7.0 11.3 7.9 19.7 8.7 13.5 6.5 11.1 14.2 8.2 14.1 23.1 12.5 9.5 5.4 4.7 7.1 9.5 14.4 9.0 11.1 11.0 5.3 10.9 14.2 15.0 5.8 8.6 8.9 15.8 0.0 20.2 10.4 24.7 15.7 15.7 12.6 18.9 14.4 12.0 14.1 10.3 UBL7 "BMSC-UbP, MGC14421" ENSG00000138629 "Ubiquitin like 7" Q96S82 15 74445977-74461182 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 175.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040423, HPA041897" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 5: NTERA-2 - Transcription" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Cytosol "HPA040423: AB_10673442, HPA041897: AB_2677732" "unprognostic (4.21e-2)" "prognostic favorable (6.37e-5)" "unprognostic (2.93e-3)" "unprognostic (5.56e-2)" "unprognostic (1.83e-1)" "unprognostic (1.60e-1)" "unprognostic (3.43e-2)" "unprognostic (1.29e-1)" "unprognostic (1.80e-1)" "unprognostic (6.71e-2)" "unprognostic (5.80e-2)" "unprognostic (2.62e-1)" "unprognostic (4.47e-3)" "unprognostic (8.94e-3)" "unprognostic (7.05e-2)" "unprognostic (2.75e-1)" "unprognostic (3.43e-2)" 33.8 38.4 27.0 13.5 28.9 15.9 32.9 26.7 35.0 34.0 23.9 48.1 15.0 36.8 15.4 37.8 30.3 10.6 67.9 29.4 26.9 38.1 32.0 29.7 21.4 28.2 27.3 31.1 44.7 25.0 30.3 15.6 29.2 36.4 16.5 13.1 34.2 16.3 114.6 54.3 36.9 18.4 25.5 48.2 43.5 55.8 25.9 27.3 37.0 37.8 29.6 38.7 33.1 29.0 18.7 20.3 31.6 42.3 32.4 42.1 21.8 29.8 36.0 37.6 46.6 24.7 26.4 27.2 31.1 35.9 48.6 29.4 88.4 40.4 36.5 36.0 55.6 35.8 32.2 45.3 31.7 22.4 29.1 32.9 35.5 32.1 43.0 32.3 32.0 60.8 30.9 39.3 39.3 26.2 28.1 35.3 75.7 31.2 24.6 29.4 25.0 60.5 32.6 21.2 31.1 61.8 28.8 26.8 40.1 44.1 28.6 36.7 18.8 34.6 20.4 17.4 37.5 39.8 82.1 30.5 22.7 40.3 30.6 32.9 51.6 59.7 35.1 58.5 33.7 50.5 35.3 37.1 70.6 55.3 33.9 40.6 65.3 55.5 55.5 151.5 65.6 52.1 27.0 28.9 26.7 35.0 29.4 26.9 28.2 27.3 29.2 25.5 25.9 29.0 17.3 32.1 18.2 3.9 35.4 15.8 24.1 35.6 26.7 5.8 24.9 23.9 29.9 18.6 20.0 14.7 8.4 71.1 36.8 25.5 58.7 37.3 75.3 12.7 13.0 20.7 23.4 45.8 5.7 34.7 66.9 20.7 22.4 13.5 19.0 21.5 22.5 16.3 41.9 5.0 3.8 26.9 20.3 38.3 31.4 175.8 24.5 31.4 21.4 5.6 82.6 18.2 23.7 4.0 4.5 29.5 27.6 21.1 51.6 19.5 48.9 44.6 16.1 9.0 19.7 13.5 50.5 59.2 31.1 29.8 25.1 68.4 23.0 19.6 28.0 25.2 UGT1A1 "GNT1, UGT1, UGT1A" ENSG00000241635 "UDP glucuronosyltransferase family 1 member A1" P22309 2 233760270-233773300 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 26 "intestine: 201.2;liver: 322.4" "Cell type enriched" "Detected in some" 7 "Hepatocytes: 105.0" "Cancer enriched" "Detected in some" 19 "liver cancer: 16.4" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in single" "neutrophil: 1.4" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.4" "Cell line enhanced" "Detected in some" "HaCaT: 14.0;OE19: 64.5;RT4: 34.7" "Not detected" "Not detected" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (7.28e-2)" "unprognostic (2.49e-2)" "unprognostic (3.60e-1)" "unprognostic (5.69e-2)" "unprognostic (4.17e-3)" "unprognostic (6.31e-3)" "unprognostic (1.94e-5)" "unprognostic (2.78e-3)" "unprognostic (2.99e-4)" 0.1 0.1 0.6 0.2 0.5 0.5 0.2 1.5 0.8 0.1 0.2 3.0 201.2 0.2 0.4 3.5 0.1 1.0 0.2 0.4 0.8 4.0 322.4 0.2 0.3 0.2 0.2 0.2 0.1 0.1 0.0 0.1 0.2 0.2 2.4 0.9 0.5 0.3 0.1 1.8 79.2 0.1 0.0 0.2 2.4 0.6 0.3 0.1 0.2 0.1 0.3 10.0 0.9 0.6 0.3 1.1 0.2 0.2 0.1 0.1 0.6 0.0 0.0 0.0 0.1 5.4 0.3 0.2 2.5 0.1 0.1 14.0 0.0 0.2 0.0 0.2 0.1 0.1 0.6 1.6 0.0 0.5 0.2 0.2 0.6 0.0 0.0 0.1 0.0 0.3 0.2 0.6 0.0 0.8 0.1 0.3 0.5 64.5 6.5 0.1 0.1 0.6 0.0 34.7 0.2 0.4 2.6 0.4 0.0 0.2 0.2 0.0 0.1 0.2 0.1 0.3 0.0 0.2 0.2 0.1 0.7 0.4 0.2 0.9 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.2 0.1 0.1 1.4 0.3 0.1 0.1 0.1 0.0 0.6 0.5 1.5 0.8 0.4 0.8 0.2 0.2 0.2 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.6 0.0 0.0 0.0 0.0 0.0 3.7 1.8 0.0 0.0 0.0 1.8 0.0 0.1 2.9 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 1.1 105.0 0.0 0.0 0.0 0.4 0.0 2.4 0.0 1.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.6 0.0 0.1 6.9 14.6 2.2 1.5 0.0 0.0 0.4 0.1 0.2 0.1 1.5 0.0 0.0 0.1 0.0 0.7 7.3 UGT1A6 "GNT1, HLUGP, UGT1F" ENSG00000167165 "UDP glucuronosyltransferase family 1 member A6" P19224 2 233691607-233773300 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "kidney: 71.3;liver: 143.3;urinary bladder: 88.8" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 12.5;Early spermatids: 52.4;Gastric mucus-secreting cells: 14.3;Late spermatids: 23.3;Squamous epithelial cells: 17.3" "Group enriched" "Detected in many" 5 "liver cancer: 7.2;lung cancer: 3.1;renal cancer: 7.6;urothelial cancer: 3.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "OE19: 1194.0" "Not detected" "Not detected" "CAB009819, HPA054065, HPA056023" Enhanced Supported "Endoplasmic reticulum,Vesicles" NA NA "Cluster 85: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 34: Spermatids - Unknown function" Vesicles "Endoplasmic reticulum" "CAB009819: AB_2241481, HPA054065: AB_2682367, HPA056023: " "unprognostic (9.09e-2)" "unprognostic (6.07e-2)" "unprognostic (5.43e-2)" "unprognostic (6.03e-2)" "prognostic unfavorable (2.89e-6)" "unprognostic (2.79e-1)" "unprognostic (6.18e-2)" "unprognostic (2.09e-3)" "unprognostic (9.97e-2)" "unprognostic (2.16e-2)" "unprognostic (3.52e-1)" "unprognostic (7.50e-2)" "unprognostic (2.01e-2)" 0.1 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 1.8 0.0 1.8 5.8 0.1 2.6 16.1 0.0 3.5 0.0 0.0 0.0 71.3 143.3 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 1.1 1.3 0.0 2.6 3.6 0.0 11.1 2.6 0.0 0.0 0.0 17.4 0.4 0.0 1.2 0.5 0.0 5.8 88.8 5.5 0.0 4.2 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 53.8 1.6 0.0 80.2 0.1 0.8 294.5 0.1 4.0 0.0 0.0 0.0 0.0 0.3 1.3 0.0 0.0 0.3 0.0 31.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 6.2 0.0 0.0 0.0 1194.0 0.0 0.1 0.2 0.1 3.2 149.0 0.0 0.0 7.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.6 1.2 12.5 0.0 0.0 0.0 0.3 0.0 2.9 1.8 0.0 0.0 0.0 0.4 0.0 0.0 52.4 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 14.3 0.5 0.0 0.0 0.4 5.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 23.3 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.9 0.5 1.8 0.1 0.0 0.0 0.0 0.0 1.2 0.2 17.3 1.1 0.0 0.0 0.0 0.1 3.0 UGT8 CGT ENSG00000174607 "UDP glycosyltransferase 8" Q16880 4 114598770-114678225 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 266.4" "Cell type enriched" "Detected in many" 8 "Oligodendrocytes: 821.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "memory B-cell: 6.9;naive B-cell: 10.7" "Lineage enriched" "Detected in single" 12 "B-cells: 10.7" "Cell line enhanced" "Detected in many" "CAPAN-2: 58.4;OE19: 123.7;RPTEC TERT1: 55.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014405, HPA065785" Enhanced Approved Mitochondria No No "Cluster 19: B-cells - Humoral immune response" "Cluster 70: Brain - Nervous system development" "Cluster 21: OE19 - Mitochondria" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Mitochondria "HPA014405: AB_1858606, HPA065785: AB_2685559" "unprognostic (7.38e-3)" "unprognostic (2.07e-1)" "unprognostic (1.25e-2)" "unprognostic (2.38e-1)" "unprognostic (1.63e-1)" "unprognostic (1.63e-2)" "unprognostic (1.16e-2)" "unprognostic (2.38e-1)" "unprognostic (7.78e-2)" "unprognostic (1.56e-3)" "unprognostic (4.49e-2)" "unprognostic (2.76e-1)" "prognostic favorable (8.55e-5)" "unprognostic (2.80e-1)" "unprognostic (1.78e-2)" "unprognostic (7.53e-2)" "unprognostic (1.49e-1)" 0.6 0.6 58.6 4.6 153.7 1.1 4.6 166.2 94.5 7.0 9.7 26.8 30.3 3.8 0.3 1.5 4.4 11.0 0.3 66.2 94.7 31.0 0.2 1.1 4.9 220.9 132.8 0.4 8.5 0.2 0.2 0.2 200.6 0.5 27.7 2.2 7.3 0.7 0.5 2.2 27.7 1.6 139.2 1.7 16.8 5.0 132.4 0.6 13.5 0.4 5.0 0.6 0.6 266.4 0.6 0.2 4.4 0.6 0.3 0.0 0.7 0.2 0.0 0.1 3.4 17.7 58.4 17.6 1.2 0.2 13.8 25.8 0.0 0.1 0.1 0.3 14.3 0.3 24.6 0.0 0.0 0.4 0.4 0.0 0.0 0.1 0.0 5.4 0.1 0.2 16.1 3.0 0.1 0.3 0.3 1.7 6.4 123.7 8.8 1.6 28.9 0.3 55.2 0.6 31.4 4.6 0.2 5.4 0.8 1.1 0.9 5.4 1.0 1.1 19.2 0.7 19.6 6.3 0.8 0.6 29.2 0.9 17.9 0.2 0.0 0.8 0.0 0.0 0.6 6.9 0.0 0.0 0.0 10.7 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.3 58.6 153.7 166.2 94.5 66.2 94.7 220.9 132.8 200.6 139.2 132.4 266.4 0.1 6.4 1.5 1.0 22.0 0.0 1.8 0.3 6.8 0.0 5.7 6.1 0.8 8.6 3.9 25.8 0.0 0.0 0.1 19.0 9.8 1.4 9.2 9.6 1.7 0.5 48.4 0.0 1.0 13.1 0.0 0.6 19.4 21.4 0.0 0.2 0.0 0.0 0.0 0.0 3.7 27.9 0.0 0.0 0.0 3.5 1.2 0.5 1.8 2.8 0.0 0.0 0.0 98.5 821.1 10.8 14.6 0.0 4.0 0.7 24.2 1.4 1.5 0.0 0.0 0.0 0.4 20.9 34.0 5.9 0.1 0.0 0.4 0.1 26.9 0.9 UNC45A "GC-UNC45, SMAP-1" ENSG00000140553 "Unc-45 myosin chaperone A" Q9H3U1 15 90930180-90954093 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Myogenesis" "Chaperone, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039228 Approved Supported "Nuclear speckles,Cytosol" NA NA 17000 "Cluster 27: Non-specific - Gene expression" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 55: Plasma cells - Humoral immune response" "Nuclear speckles" Cytosol "HPA039228: AB_2676402" "unprognostic (1.46e-1)" "unprognostic (3.83e-2)" "unprognostic (4.51e-2)" "unprognostic (1.97e-1)" "unprognostic (2.68e-2)" "unprognostic (1.70e-3)" "prognostic unfavorable (7.72e-4)" "unprognostic (2.27e-2)" "unprognostic (1.58e-1)" "unprognostic (1.16e-1)" "unprognostic (1.98e-1)" "unprognostic (9.85e-2)" "prognostic favorable (7.46e-7)" "unprognostic (9.30e-2)" "unprognostic (1.74e-1)" "unprognostic (1.95e-1)" "unprognostic (2.28e-2)" 25.0 25.3 7.7 16.7 8.2 17.3 23.2 8.6 9.1 32.0 10.0 41.2 16.4 38.1 11.0 31.4 28.4 17.3 15.9 7.8 7.7 18.9 13.0 20.2 18.9 8.9 11.6 26.1 22.3 33.2 17.5 19.6 9.5 25.2 13.4 5.6 25.8 34.1 9.6 37.7 23.5 28.0 8.3 19.7 28.5 13.1 9.6 18.0 19.5 10.6 17.3 39.3 29.4 8.0 38.2 76.3 30.9 27.2 83.0 38.0 27.3 42.4 36.2 56.5 45.1 61.3 49.4 44.7 55.5 53.8 32.5 82.1 52.9 54.4 26.6 49.8 75.9 86.2 77.0 44.4 46.8 21.5 56.2 47.3 65.8 55.7 40.5 54.2 77.5 35.1 38.6 35.8 43.3 62.2 28.1 18.6 41.8 69.5 38.0 54.8 46.9 48.1 38.4 89.2 43.1 39.4 57.1 55.9 54.3 36.8 50.8 44.3 77.0 48.0 34.1 40.4 45.0 33.6 50.5 21.1 46.6 49.7 49.8 11.5 8.3 5.0 11.8 7.3 11.3 7.9 9.6 9.1 10.4 6.3 7.8 7.4 1.6 9.8 11.6 9.1 9.3 9.8 7.7 8.2 8.6 9.1 7.8 7.7 8.9 11.6 9.5 8.3 9.6 8.0 21.7 22.4 22.4 9.4 23.2 16.3 24.8 26.1 30.1 27.2 17.2 19.6 12.7 35.8 23.8 18.4 18.8 53.6 17.5 26.9 13.7 33.6 26.7 12.8 20.3 25.3 37.0 25.2 19.1 18.2 22.7 23.7 26.5 22.1 29.2 30.9 18.9 13.4 28.2 18.5 18.4 15.9 26.4 12.2 14.0 29.0 29.5 20.7 19.6 9.4 28.8 21.5 27.8 7.1 11.0 23.3 26.0 51.6 20.6 16.8 22.0 19.6 11.7 35.1 32.9 15.2 33.9 24.8 6.4 33.9 18.8 46.2 21.4 26.0 22.7 20.3 USP2 UBP41 ENSG00000036672 "Ubiquitin specific peptidase 2" O75604 11 119355215-119381711 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Myogenesis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 168.3" "Group enriched" "Detected in many" 5 "Early spermatids: 460.0;Late spermatids: 1094.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "K-562: 14.5;U-266/70: 56.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006777, HPA007222" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 54: Non-specific - Microtubule organization" "Cluster 29: U-266 - Adaptive immune response" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "Plasma membrane" "HPA006777: AB_1080507, HPA007222: AB_1080505" "unprognostic (6.83e-2)" "unprognostic (2.02e-2)" "unprognostic (5.54e-2)" "unprognostic (1.37e-2)" "unprognostic (1.25e-1)" "unprognostic (7.46e-3)" "unprognostic (1.00e-1)" "unprognostic (5.27e-2)" "unprognostic (1.24e-1)" "unprognostic (5.24e-3)" "unprognostic (8.02e-3)" "unprognostic (7.33e-2)" "prognostic favorable (3.09e-11)" "unprognostic (1.58e-1)" "unprognostic (1.20e-1)" "unprognostic (1.96e-2)" "unprognostic (2.66e-2)" 7.0 13.4 11.9 1.6 22.6 1.9 4.1 18.8 19.0 6.0 32.7 10.2 13.9 5.2 5.7 9.8 11.6 2.3 73.5 18.6 9.4 53.4 18.9 3.4 0.1 12.0 13.1 6.2 18.1 24.2 18.9 1.3 7.7 4.1 6.0 76.2 7.6 3.0 168.3 12.8 17.4 6.8 8.2 0.6 6.2 86.5 15.1 0.6 3.8 62.8 0.6 4.5 4.8 17.5 6.0 0.5 0.9 3.2 0.1 0.2 1.3 0.7 0.4 0.0 0.6 6.1 0.8 10.2 1.8 1.1 1.4 1.0 7.9 2.9 0.2 7.2 1.0 2.8 4.4 12.5 2.7 0.0 2.8 0.9 0.6 0.7 2.0 1.3 0.6 7.6 14.5 0.8 1.7 4.1 0.0 0.6 1.6 2.0 1.3 0.1 2.1 1.5 4.6 0.3 11.9 3.6 3.4 2.6 0.7 1.7 8.8 6.2 0.0 0.0 1.5 0.8 1.0 56.9 13.5 0.2 0.1 2.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.9 22.6 18.8 19.0 18.6 9.4 12.0 13.1 7.7 8.2 15.1 17.5 0.6 3.2 2.7 10.7 0.6 2.4 5.3 1.5 1.2 75.2 3.3 2.4 85.2 7.2 6.1 5.5 95.9 0.5 1.6 25.5 113.5 3.1 460.0 39.0 3.0 3.6 0.0 0.4 15.7 1.6 0.9 7.4 2.0 8.4 0.0 2.0 2.2 23.0 17.2 10.1 11.6 2.0 0.0 1.3 2.9 1094.1 6.5 2.1 0.0 1.9 0.0 49.7 0.0 8.0 12.5 1.2 11.8 7.2 0.1 1.1 41.3 41.6 35.0 140.0 19.7 43.3 24.0 50.5 16.5 12.9 4.0 1.4 1.3 0.5 2.6 2.9 UTP18 "CGI-48, WDR50" ENSG00000011260 "UTP18 small subunit processome component" Q9Y5J1 17 51260546-51297936 "Predicted intracellular proteins" "rRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 190.6;Late spermatids: 182.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052378 Approved Supported "Nucleoplasm,Nuclear membrane,Nucleoli,Nucleoli rim" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoli, Nucleoli rim" "Nucleoplasm, Nuclear membrane" "HPA052378: AB_2681805" "unprognostic (1.36e-2)" "unprognostic (1.00e-1)" "prognostic favorable (3.33e-4)" "unprognostic (2.62e-2)" "unprognostic (2.55e-2)" "unprognostic (5.99e-2)" "prognostic unfavorable (1.99e-4)" "unprognostic (2.47e-2)" "unprognostic (8.37e-3)" "unprognostic (1.10e-2)" "unprognostic (8.82e-2)" "unprognostic (2.75e-2)" "unprognostic (3.11e-3)" "unprognostic (9.51e-2)" "unprognostic (1.59e-1)" "unprognostic (8.72e-3)" "unprognostic (1.93e-2)" 17.9 20.1 12.6 24.9 13.7 40.0 25.8 19.1 15.7 18.8 14.2 17.5 17.8 15.7 15.8 21.0 17.5 12.8 10.2 13.2 13.8 21.8 22.3 17.3 33.1 13.0 12.3 23.8 21.3 23.3 20.4 26.3 13.6 16.2 18.7 17.5 17.4 14.2 24.4 32.3 16.5 12.9 13.0 24.5 18.1 58.7 13.2 27.7 24.4 16.2 34.4 24.8 18.0 15.6 90.5 87.7 54.6 50.3 35.1 52.2 142.2 48.9 40.2 83.5 79.7 55.4 49.3 113.5 67.8 36.6 89.0 48.1 89.7 52.0 123.3 74.8 117.0 119.4 52.6 97.3 48.0 127.9 56.4 33.9 39.5 71.1 57.0 42.1 50.7 55.6 98.7 50.6 63.5 56.1 115.6 86.9 78.5 127.5 91.8 103.2 124.2 89.4 61.3 59.1 60.7 76.9 56.7 66.6 114.7 67.4 82.3 64.4 44.7 85.3 71.8 71.1 102.9 97.4 192.5 131.5 53.0 87.6 62.4 19.0 48.2 27.9 40.2 46.9 49.9 54.1 50.7 49.2 55.9 52.4 53.6 51.1 8.2 40.0 49.0 35.0 56.8 56.2 12.6 13.7 19.1 15.7 13.2 13.8 13.0 12.3 13.6 13.0 13.2 15.6 20.6 16.0 23.4 11.8 37.4 60.2 62.9 40.6 33.0 15.6 19.6 17.9 4.4 20.0 25.2 14.7 14.6 66.7 27.4 11.4 39.2 38.4 190.6 26.3 27.3 25.1 16.1 20.8 18.5 46.9 71.2 24.5 14.3 24.1 31.7 19.6 8.9 17.1 62.8 10.1 18.0 20.7 34.6 37.7 26.1 182.0 26.8 33.3 23.2 15.0 42.2 21.3 25.7 17.6 24.6 34.2 16.3 22.2 24.2 50.2 13.8 37.5 38.8 11.8 13.1 24.8 35.7 140.2 104.5 27.7 52.7 79.6 30.4 30.8 25.3 48.1 VAMP8 EDB ENSG00000118640 "Vesicle associated membrane protein 8" Q9BV40 2 85561562-85582031 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiviral defense, Autophagy, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HL-60: 873.4;NB-4: 1362.5;U-937: 912.8" "Low region specificity" "Detected in all" "HPA006882, HPA007215, CAB037132, CAB037147" Enhanced Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA 220000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 24: NB-4 - Immune response" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Golgi apparatus, Plasma membrane" Nucleoplasm "CAB037132: AB_1080547, CAB037147: AB_1080544, HPA006882: AB_1858716, HPA007215: " "unprognostic (1.00e-1)" "unprognostic (1.16e-1)" "unprognostic (7.46e-3)" "unprognostic (1.13e-1)" "unprognostic (7.33e-2)" "unprognostic (1.31e-1)" "unprognostic (1.76e-2)" "unprognostic (3.79e-3)" "unprognostic (3.83e-2)" "unprognostic (4.15e-1)" "unprognostic (2.74e-2)" "unprognostic (8.62e-2)" "unprognostic (1.57e-3)" "unprognostic (1.92e-2)" "unprognostic (2.16e-1)" "prognostic favorable (8.07e-9)" "prognostic favorable (1.59e-6)" 74.0 34.7 26.9 148.4 28.2 299.7 225.1 28.7 53.8 121.8 51.6 250.6 229.9 30.6 144.5 303.1 166.1 119.2 24.6 26.5 29.9 280.1 247.4 266.5 212.4 35.6 31.6 10.4 182.5 270.3 33.7 265.7 34.3 107.7 300.9 4.4 322.5 90.4 24.3 210.2 252.1 71.4 31.9 175.9 228.4 23.4 35.5 173.5 126.0 27.3 311.7 198.0 150.0 36.5 255.0 33.2 2.6 2.3 2.4 1.4 241.6 0.7 0.3 0.2 0.3 191.2 225.2 56.8 174.4 1.2 17.9 175.2 2.4 451.6 0.6 232.3 173.7 290.3 104.4 220.7 3.3 873.4 287.1 2.3 317.5 0.3 72.3 1.2 58.2 1.2 214.9 11.6 103.8 363.9 0.8 1362.5 3.2 315.9 26.0 5.2 8.9 381.7 516.9 384.3 8.4 2.9 120.9 628.3 19.4 126.3 231.4 665.4 113.9 0.3 15.3 2.9 2.7 3.0 151.1 340.0 2.6 912.8 1.1 601.3 868.6 328.4 469.3 740.3 455.6 519.3 537.0 463.3 787.3 508.3 423.2 442.0 52.4 556.3 460.0 2135.6 665.3 1536.0 26.9 28.2 28.7 53.8 26.5 29.9 35.6 31.6 34.3 31.9 35.5 36.5 39.4 371.8 283.2 1.3 147.7 259.1 303.3 800.9 164.4 1.2 289.7 251.7 6.3 356.0 662.1 366.0 0.0 980.8 447.1 832.3 765.0 630.7 28.0 231.3 22.8 46.1 129.1 147.4 0.1 730.0 460.4 35.6 188.6 212.9 269.4 3.3 163.1 314.8 1191.1 0.0 0.1 391.8 545.3 1000.4 488.7 49.1 9.3 537.2 352.2 2.8 686.1 7.9 375.9 0.0 0.5 865.5 843.2 7.5 103.0 302.7 1184.0 1046.8 600.5 2.0 46.0 21.4 56.5 48.0 8.3 239.8 329.7 877.8 219.5 13.8 299.4 602.0 VAT1 "FLJ20230, VATI" ENSG00000108828 "Vesicle amine transport 1" Q99536 17 43014607-43025123 "Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 133.2;Hofbauer cells: 146.4;Melanocytes: 122.7" "Cancer enhanced" "Detected in all" "melanoma: 295.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 4 "basophil: 104.0" "Lineage enriched" "Detected in all" 5 "granulocytes: 104.0" "Cell line enhanced" "Detected in all" "SK-MEL-30: 680.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045170 Uncertain NA NA 2700000 "Cluster 46: Basophils - DNA binding" "Cluster 31: Skin - Epidermis development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA045170: AB_10964166" "unprognostic (2.22e-2)" "unprognostic (4.41e-3)" "unprognostic (6.86e-3)" "unprognostic (1.16e-1)" "unprognostic (1.22e-1)" "unprognostic (9.67e-2)" "prognostic unfavorable (1.39e-4)" "unprognostic (1.16e-2)" "unprognostic (5.56e-2)" "unprognostic (1.86e-2)" "unprognostic (1.17e-3)" "unprognostic (2.38e-1)" "prognostic favorable (5.89e-4)" "unprognostic (1.71e-2)" "unprognostic (3.66e-2)" "unprognostic (1.07e-1)" "unprognostic (3.36e-2)" 180.4 251.5 53.6 32.1 57.6 86.5 137.5 55.3 67.3 160.8 54.8 97.5 25.7 121.4 65.0 132.6 78.4 85.6 74.7 47.3 129.9 70.5 44.5 111.7 29.0 88.4 132.3 184.8 67.2 54.7 103.7 83.9 173.9 64.9 32.9 7.6 86.3 52.2 29.2 194.3 65.1 94.2 60.5 40.3 56.1 79.2 93.3 63.7 68.3 45.8 33.7 109.5 126.3 77.3 38.9 225.0 53.6 119.0 556.9 435.5 75.5 94.2 282.1 89.7 167.1 139.7 83.2 7.7 128.8 395.8 283.7 58.9 94.1 81.6 82.7 14.4 127.6 36.2 107.3 279.5 357.7 177.6 271.5 234.3 119.2 154.0 71.2 203.8 428.9 230.5 77.3 12.1 227.3 37.2 262.2 76.6 68.1 111.6 106.2 37.3 66.1 19.4 102.2 76.6 50.0 94.6 51.3 29.5 680.8 217.9 82.5 99.4 431.7 199.9 92.5 226.2 22.9 19.4 30.2 14.3 203.1 132.0 31.4 104.0 16.6 24.9 13.1 7.9 15.3 19.9 18.5 13.6 8.4 19.5 16.8 10.4 5.1 11.1 9.2 4.1 13.4 19.0 53.6 57.6 55.3 67.3 47.3 129.9 88.4 132.3 173.9 60.5 93.3 77.3 133.2 22.4 13.9 1.0 17.2 28.4 14.2 17.9 34.1 1.1 29.5 30.2 31.6 17.2 10.7 23.9 4.2 6.5 6.5 9.2 17.6 99.7 27.5 14.2 32.5 71.0 15.1 12.6 2.3 43.4 45.1 91.4 8.2 32.6 77.2 93.8 73.9 15.8 146.4 5.0 2.4 4.1 4.1 40.0 32.4 45.2 51.9 43.9 122.7 6.5 16.1 4.2 3.1 3.5 4.1 49.6 10.4 58.6 19.6 25.5 36.5 60.1 12.6 1.8 13.1 19.4 39.1 12.8 15.5 35.1 33.5 11.1 12.6 31.2 4.7 21.8 VPS33B FLJ14848 ENSG00000184056 "VPS33B late endosome and lysosome associated" Q9H267 15 90998673-91022603 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA040415 Approved NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 27: Brain & Skin - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "HPA040415: AB_10795419" "unprognostic (7.49e-2)" "unprognostic (1.40e-1)" "unprognostic (1.15e-1)" "unprognostic (2.55e-2)" "unprognostic (3.06e-1)" "unprognostic (1.79e-2)" "unprognostic (2.97e-2)" "unprognostic (2.42e-2)" "unprognostic (1.30e-1)" "unprognostic (2.84e-3)" "unprognostic (2.78e-2)" "unprognostic (7.94e-2)" "unprognostic (3.70e-1)" "unprognostic (6.75e-2)" "unprognostic (6.04e-2)" "unprognostic (8.24e-2)" "unprognostic (1.00e-2)" 5.7 5.4 5.9 5.1 7.2 2.8 6.1 6.3 7.6 6.6 6.7 6.7 5.8 6.3 7.0 6.8 8.1 4.7 3.8 6.6 7.1 5.9 4.3 5.6 6.9 6.3 6.3 6.8 6.9 8.1 5.3 6.8 6.4 6.6 6.4 5.8 6.7 6.7 4.1 11.0 6.9 6.2 6.3 6.9 7.9 6.1 7.2 5.4 5.5 4.3 6.5 6.1 6.4 7.7 5.6 16.4 3.4 6.0 8.9 15.1 17.7 6.8 12.7 10.7 10.9 7.0 11.0 7.1 9.4 11.9 9.6 10.0 4.7 10.3 5.6 3.8 4.9 7.7 6.6 10.3 10.9 9.6 10.3 17.0 10.7 8.0 9.5 9.3 15.2 8.6 12.6 1.7 7.9 11.9 6.5 6.8 8.3 14.8 5.8 4.9 8.9 8.7 12.2 12.3 5.2 9.6 10.0 7.9 17.5 8.1 8.1 12.6 10.4 7.0 7.8 5.0 5.2 3.6 12.9 2.7 14.7 9.3 6.4 12.5 7.1 12.1 7.7 11.8 8.9 5.6 6.8 6.9 9.5 7.8 7.8 11.0 3.2 7.9 13.4 4.7 5.9 6.4 5.9 7.2 6.3 7.6 6.6 7.1 6.3 6.3 6.4 6.3 7.2 7.7 2.2 0.0 7.3 5.5 5.3 2.2 3.0 3.5 1.8 9.2 2.6 1.8 4.8 2.8 4.4 3.7 2.1 16.8 5.0 6.9 5.9 9.0 3.1 3.0 2.7 4.7 2.4 5.7 11.4 9.4 10.8 2.9 7.7 2.9 8.2 6.7 5.7 4.9 8.0 8.4 11.3 5.1 4.1 6.0 4.1 4.0 3.7 4.5 8.8 3.7 7.7 6.3 3.1 7.5 9.7 9.3 5.0 5.3 4.9 4.1 7.9 4.3 7.9 7.0 6.6 2.7 3.5 11.0 8.2 2.3 2.6 12.3 5.0 3.6 4.3 3.0 VPS37C FLJ20847 ENSG00000167987 "VPS37C subunit of ESCRT-I" A5D8V6 11 61130257-61161615 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 1.4;eosinophil: 1.7;intermediate monocyte: 2.6;myeloid DC: 1.0;neutrophil: 3.8;non-classical monocyte: 2.4" "Group enriched" "Detected in many" 5 "dendritic cells: 1.0;granulocytes: 3.8;monocytes: 2.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043348 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 46: Photoreceptor cells - Phototransduction" Vesicles Nucleoplasm "HPA043348: AB_10794658" "unprognostic (1.97e-1)" "unprognostic (1.35e-1)" "unprognostic (2.50e-1)" "unprognostic (7.95e-3)" "unprognostic (3.38e-1)" "unprognostic (9.01e-2)" "prognostic unfavorable (5.85e-5)" "unprognostic (7.42e-2)" "unprognostic (1.14e-1)" "unprognostic (3.00e-1)" "unprognostic (3.41e-2)" "unprognostic (3.17e-2)" "prognostic favorable (2.37e-7)" "unprognostic (1.99e-1)" "unprognostic (1.08e-1)" "unprognostic (3.85e-1)" "unprognostic (7.05e-2)" 14.1 13.8 11.5 13.2 10.9 10.3 14.0 10.0 12.2 14.3 11.9 17.7 17.1 15.9 5.2 22.0 12.5 11.2 15.8 12.6 9.9 16.8 10.7 14.5 8.1 11.9 11.6 14.1 24.1 11.9 20.1 14.1 10.5 20.9 10.5 22.7 23.3 14.6 23.6 22.2 15.5 14.5 9.6 13.3 27.7 15.3 12.0 6.2 12.1 11.8 10.0 18.3 15.9 11.4 33.8 13.1 16.7 16.1 8.0 16.6 37.2 16.4 44.0 23.9 16.2 15.7 15.6 8.8 22.5 22.5 19.7 18.5 15.2 17.3 12.3 19.2 11.4 11.2 9.0 17.8 25.7 9.0 13.7 15.0 26.3 20.6 25.7 14.3 15.8 6.0 29.6 14.6 16.4 41.1 2.0 13.7 20.6 14.7 18.8 3.1 7.2 21.4 18.9 17.2 10.3 25.1 16.4 52.2 28.8 14.0 49.5 22.2 12.1 23.9 17.2 24.4 20.8 6.9 10.0 7.2 21.6 11.1 16.5 0.4 1.4 1.7 0.3 2.6 0.4 0.5 0.2 0.4 1.0 0.5 0.3 0.1 3.8 0.2 2.4 0.1 0.2 0.7 11.5 10.9 10.0 12.2 12.6 9.9 11.9 11.6 10.5 9.6 12.0 11.4 6.3 16.0 6.0 5.9 4.1 12.5 14.3 9.4 10.2 5.8 14.9 9.3 7.5 12.8 10.0 12.9 10.4 30.6 1.2 15.6 11.7 17.4 8.9 5.0 4.0 11.2 16.3 4.2 8.9 19.8 20.9 10.6 13.7 6.8 0.0 5.1 7.1 6.7 17.3 25.2 7.1 18.3 8.2 13.7 11.4 6.5 7.8 13.9 7.2 13.1 12.3 11.5 2.1 4.5 8.3 21.7 11.3 13.5 2.2 17.7 19.0 7.2 12.2 41.7 0.0 6.7 9.2 12.9 16.7 8.4 19.9 35.2 2.9 7.4 10.6 14.5 VSIG10L2 ENSG00000283703 "V-set and immunoglobulin domain containing 10 like 2" P0DP72 11 125946056-125958647 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 6 "skin 1: 18.6" "Group enriched" "Detected in some" 4 "Breast glandular cells: 11.9;Breast myoepithelial cells: 6.7" "Region enhanced" "Detected in single" "cerebellum: 3.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" "Cluster 35: Glandular cells - Unknown function" 0.2 0.0 0.1 0.0 0.2 0.0 1.8 3.2 0.8 0.8 0.0 0.0 0.0 0.3 0.0 0.8 0.3 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.1 0.0 18.6 0.0 0.7 0.0 0.9 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 3.2 0.8 0.3 0.1 0.1 0.0 0.3 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.9 6.7 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.2 0.1 0.1 0.0 0.0 0.0 1.1 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 VSIG4 "CRIg, Z39IG" ENSG00000155659 "V-set and immunoglobulin domain containing 4" Q9Y279 X 66021738-66040125 "Plasma proteins, Predicted membrane proteins" "Complement alternate pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 166.0" "Group enriched" "Detected in many" 5 "Hofbauer cells: 989.8;Kupffer cells: 590.9;Macrophages: 328.4" "Cancer enriched" "Detected in all" 5 "glioma: 88.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 27 "classical monocyte: 18.7;intermediate monocyte: 11.1;myeloid DC: 17.8" "Group enriched" "Detected in many" 31 "dendritic cells: 17.8;monocytes: 18.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA003903, CAB026000" Enhanced Uncertain "Nucleoli,Plasma membrane,Cytosol" NA NA 59000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 19: Lung - Lung function" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane, Cytosol" Nucleoli "CAB026000: , HPA003903: AB_1858776" "unprognostic (6.87e-3)" "unprognostic (4.79e-2)" "prognostic unfavorable (1.34e-4)" "unprognostic (3.19e-1)" "unprognostic (1.30e-2)" "unprognostic (1.53e-2)" "unprognostic (9.37e-3)" "unprognostic (1.24e-1)" "unprognostic (3.10e-1)" "unprognostic (1.37e-3)" "unprognostic (1.06e-1)" "unprognostic (2.77e-1)" "prognostic unfavorable (1.95e-6)" "unprognostic (3.70e-2)" "unprognostic (5.45e-2)" "unprognostic (3.37e-2)" "unprognostic (3.47e-2)" 137.1 68.8 17.9 44.2 18.8 7.8 44.2 17.0 36.6 14.1 21.5 40.9 22.5 15.5 5.3 15.4 66.8 39.6 30.0 18.2 18.3 17.9 51.0 166.0 27.8 25.1 23.6 12.9 14.3 6.8 7.0 139.6 25.8 10.6 31.7 2.2 24.5 9.3 8.2 10.8 43.9 108.3 18.9 69.3 22.9 7.3 37.6 5.4 12.3 12.5 1.8 61.5 11.6 26.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 18.7 0.1 0.0 11.1 0.0 0.0 0.0 0.2 17.8 0.1 0.0 0.0 0.5 0.0 0.4 0.1 0.0 5.6 17.9 18.8 17.0 36.6 18.2 18.3 25.1 23.6 25.8 18.9 37.6 26.7 1.3 3.2 16.1 0.0 1.2 2.3 0.3 0.0 0.0 0.0 2.6 0.5 1.8 7.2 3.1 0.0 0.0 5.3 0.3 0.0 0.0 0.1 7.9 0.0 0.0 10.4 0.0 0.0 0.0 0.0 4.9 2.7 0.0 0.0 3.8 0.0 5.0 3.2 989.8 0.0 0.0 0.0 0.0 590.9 111.8 16.6 1.5 328.4 3.6 12.2 1.5 0.5 0.0 0.5 0.0 0.0 0.1 0.4 0.3 0.3 0.0 0.1 4.4 0.0 6.6 0.6 2.0 0.3 0.9 0.5 1.7 12.3 1.5 0.0 0.0 0.2 VWA5B1 FLJ32784 ENSG00000158816 "Von Willebrand factor A domain containing 5B1" Q5TIE3 1 20290919-20354894 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.3;choroid plexus: 19.1" "Cell type enhanced" "Detected in some" "Astrocytes: 2.6;Early spermatids: 10.9;Inhibitory neurons: 1.8;Late spermatids: 9.0" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 10 "SCLC-21H: 1.2" "Low region specificity" "Detected in many" "HPA027496, HPA028405, HPA064829" Enhanced Approved "Plasma membrane,Mitochondria,Cytosol" "Secreted in male reproductive system" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 23: Spermatids - Flagellum & Golgi organization" Mitochondria "Plasma membrane, Cytosol" "HPA027496: AB_10599853, HPA028405: AB_10600992, HPA064829: AB_2685363" "unprognostic (2.34e-1)" "unprognostic (2.91e-1)" "unprognostic (7.78e-2)" "unprognostic (1.16e-2)" "unprognostic (4.73e-2)" "unprognostic (1.21e-2)" "unprognostic (1.09e-1)" "unprognostic (1.86e-2)" "unprognostic (4.39e-2)" "unprognostic (1.73e-1)" "unprognostic (5.41e-4)" "unprognostic (7.43e-4)" "unprognostic (1.82e-2)" "unprognostic (3.33e-2)" "unprognostic (1.03e-1)" 0.0 0.4 0.8 0.1 0.9 0.0 0.0 0.1 0.1 0.0 19.1 0.0 0.0 0.0 1.3 0.0 0.3 0.2 0.0 1.1 2.9 1.3 0.0 0.1 0.1 3.7 6.3 0.0 0.0 1.1 2.9 0.1 5.1 0.0 0.0 0.1 1.7 0.3 0.0 0.0 0.0 0.0 1.5 0.0 0.0 3.2 3.0 0.0 0.2 0.4 0.0 0.4 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.9 0.1 0.1 1.1 2.9 3.7 6.3 5.1 1.5 3.0 0.7 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.9 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 9.0 0.3 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 WNT3 "INT4, MGC131950, MGC138321, MGC138323" ENSG00000108379 "Wnt family member 3" P56703 17 46762506-46833154 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "liver: 12.3;skin 1: 27.7" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 44.5;Early spermatids: 27.7;Late spermatids: 63.8;Suprabasal keratinocytes: 17.6" "Cancer enriched" "Detected in many" 6 "testis cancer: 13.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 8.5;U-698: 14.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA049893 Approved Vesicles "Secreted to extracellular matrix" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 28: Keratinocytes - Keratinization" Vesicles "HPA049893: " "unprognostic (1.84e-1)" "unprognostic (2.90e-2)" "unprognostic (2.35e-1)" "unprognostic (6.41e-4)" "unprognostic (4.73e-2)" "unprognostic (5.26e-2)" "unprognostic (1.33e-1)" "unprognostic (1.26e-1)" "unprognostic (4.97e-2)" "unprognostic (2.20e-2)" "unprognostic (2.16e-1)" "unprognostic (2.66e-1)" "unprognostic (1.10e-8)" "unprognostic (1.77e-1)" "unprognostic (2.08e-1)" "unprognostic (1.61e-1)" "unprognostic (1.38e-1)" 0.8 0.4 1.3 0.4 1.1 0.1 1.0 0.7 1.0 1.0 0.2 0.6 3.4 0.5 0.0 1.3 0.5 0.1 0.9 0.8 1.2 1.7 12.3 0.9 0.2 1.4 1.8 0.5 0.8 2.5 1.7 0.2 1.2 1.3 0.2 0.2 1.2 0.0 0.2 27.7 2.7 0.2 0.7 0.7 0.4 4.4 4.4 0.1 1.3 0.0 0.1 0.4 1.1 0.7 3.9 1.7 8.5 0.0 0.1 0.1 0.7 0.8 0.9 3.0 0.0 2.7 1.7 1.6 2.3 2.1 6.1 1.3 0.4 0.0 3.9 0.0 0.4 0.0 3.0 2.3 0.0 0.1 0.1 0.2 1.8 1.1 2.3 3.5 1.1 2.5 1.5 0.0 1.0 1.7 0.0 1.4 0.0 1.0 2.4 2.9 1.9 0.2 0.6 0.0 0.1 0.7 1.6 0.0 1.2 2.1 0.0 4.0 0.2 3.2 2.1 0.4 1.5 0.6 0.2 14.0 0.4 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 1.3 1.1 0.7 1.0 0.8 1.2 1.4 1.8 1.2 0.7 4.4 0.7 0.2 0.0 1.5 3.9 0.5 44.5 0.6 0.6 3.4 1.1 3.0 1.7 1.3 1.5 0.4 0.0 0.0 2.2 0.1 0.7 1.9 0.7 27.7 0.1 0.7 0.5 0.0 0.0 5.4 2.5 0.1 1.1 0.0 0.2 0.0 0.7 0.4 4.0 0.2 8.4 4.3 0.6 0.0 0.0 1.5 63.8 0.3 0.1 1.8 1.0 0.6 0.2 0.0 4.0 1.1 2.9 1.4 0.4 0.0 1.2 3.7 0.5 0.3 0.8 0.0 1.4 1.1 0.9 2.9 0.8 17.6 0.3 0.0 0.3 0.9 0.3 WNT4 WNT-4 ENSG00000162552 "Wnt family member 4" P56705 1 22117313-22143969 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 40.8" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 42.1;Breast glandular cells: 19.9;Breast myoepithelial cells: 24.3;Endometrial stromal cells: 71.4;Enteroendocrine cells: 29.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 8.5;SCLC-21H: 10.2;SK-BR-3: 8.6;T-47d: 3.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA011397 Uncertain Approved Vesicles "Secreted to extracellular matrix" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 31: Skin - Epidermis development" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 36: Stromal cells - Cell proliferation" Vesicles "HPA011397: AB_1858854" "unprognostic (1.85e-1)" "unprognostic (9.08e-2)" "unprognostic (6.67e-3)" "unprognostic (1.75e-2)" "unprognostic (7.17e-2)" "unprognostic (4.30e-3)" "unprognostic (2.77e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (5.34e-4)" "unprognostic (2.14e-2)" "prognostic favorable (4.90e-4)" "unprognostic (1.01e-1)" "unprognostic (2.95e-2)" "unprognostic (4.21e-1)" "unprognostic (2.32e-1)" "unprognostic (4.74e-2)" "unprognostic (9.49e-2)" 0.8 9.0 2.4 0.4 1.5 0.3 2.2 0.2 2.9 8.9 0.5 2.3 3.2 4.5 8.9 12.1 8.3 2.6 0.1 2.0 2.9 1.1 1.4 1.2 0.1 1.6 1.8 16.8 3.0 0.1 5.6 1.6 1.2 5.5 1.6 0.2 4.1 2.6 3.1 40.8 3.1 1.9 1.1 0.3 4.3 0.6 3.9 1.1 3.4 0.6 1.5 3.1 6.3 1.1 1.3 0.1 2.5 0.1 0.0 0.0 2.2 0.5 0.0 0.0 0.0 0.0 0.7 0.0 0.8 0.0 0.3 8.5 0.0 0.6 0.0 0.2 0.3 0.3 0.2 0.0 0.2 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 1.1 0.2 0.3 0.0 0.0 0.0 1.6 10.2 0.0 0.1 8.6 0.6 0.6 3.4 0.0 0.3 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 1.5 0.2 2.9 2.0 2.9 1.6 1.8 1.2 1.1 3.9 1.1 0.9 3.2 8.6 0.3 0.7 16.7 4.3 42.1 6.8 0.0 19.9 24.3 0.6 0.0 15.2 0.0 0.0 0.7 0.1 0.9 0.0 2.7 0.1 4.1 71.4 0.6 29.4 0.0 0.2 0.6 0.1 3.1 0.5 1.6 0.0 0.2 0.7 0.5 0.1 0.0 1.9 16.0 4.1 0.0 0.2 0.9 0.0 0.4 5.4 6.5 0.1 0.0 0.0 0.0 0.3 0.9 0.1 3.8 0.6 5.7 0.3 0.0 12.0 0.0 0.0 0.4 2.2 0.0 0.3 2.5 10.4 0.3 0.6 0.0 0.6 4.2 WWTR1 "DKFZp586I1419, TAZ" ENSG00000018408 "WW domain containing transcription regulator 1" Q9GZV5 3 149517235-149736714 "Cancer-related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 229.3;Endothelial cells: 221.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 212.1;RPTEC TERT1: 151.1;SK-MEL-30: 160.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007415, CAB017483, CAB068248" Enhanced Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Nuclear bodies" Cytosol "CAB017483: AB_2216639, CAB068248: AB_2665648, HPA007415: AB_1080602" "unprognostic (1.85e-2)" "unprognostic (2.24e-2)" "unprognostic (3.41e-3)" "unprognostic (1.33e-2)" "unprognostic (7.94e-2)" "unprognostic (1.37e-1)" "unprognostic (2.41e-2)" "unprognostic (2.22e-1)" "unprognostic (1.74e-2)" "unprognostic (2.34e-1)" "unprognostic (1.63e-2)" "unprognostic (3.32e-1)" "unprognostic (1.17e-3)" "unprognostic (2.76e-2)" "unprognostic (2.53e-1)" "unprognostic (3.98e-2)" "unprognostic (1.01e-3)" 41.6 13.8 19.2 22.4 20.8 0.2 37.2 18.9 19.6 41.8 32.6 74.9 8.0 42.1 13.4 35.8 33.7 39.6 36.4 20.7 53.9 45.9 19.0 41.2 7.2 52.6 39.9 43.9 31.8 14.1 13.6 44.0 35.9 34.5 13.5 4.2 27.6 32.1 13.2 24.8 21.6 43.7 37.1 19.5 32.7 7.2 23.0 4.7 31.6 15.0 6.1 59.2 34.3 41.0 58.9 80.5 40.6 48.7 48.6 86.8 43.0 32.6 57.5 17.7 17.8 46.7 53.2 0.1 212.1 45.0 53.3 36.1 28.4 28.5 17.9 22.0 19.3 0.0 18.6 37.8 27.3 0.0 0.1 45.3 7.4 61.8 26.6 65.4 136.3 0.0 0.0 0.2 61.7 9.2 0.2 0.2 8.2 0.2 96.6 0.0 50.6 0.4 151.1 9.4 0.0 0.4 21.1 17.2 160.2 31.5 26.5 1.6 94.2 29.0 16.2 24.8 67.4 0.6 0.5 0.8 66.8 0.1 78.8 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.5 0.1 19.2 20.8 18.9 19.6 20.7 53.9 52.6 39.9 35.9 37.1 23.0 41.0 125.7 64.1 89.7 60.4 1.1 51.7 229.3 34.6 60.9 2.2 58.1 56.8 46.8 141.5 87.8 49.7 4.2 12.2 2.0 0.5 7.9 72.0 21.9 136.3 89.1 221.2 0.0 3.2 8.7 27.1 82.3 77.9 10.2 144.4 7.6 45.0 111.4 21.9 4.1 0.0 6.1 1.2 10.2 6.0 32.3 7.9 57.8 4.6 30.2 94.6 2.1 11.0 0.0 7.5 12.7 45.8 0.0 126.4 2.9 86.7 1.2 59.8 53.9 2.0 59.2 76.1 58.0 2.2 0.8 46.3 35.5 14.8 6.5 48.4 2.4 93.5 ZBTB10 "FLJ12752, RINZF" ENSG00000205189 "Zinc finger and BTB domain containing 10" Q96DT7 8 80485619-80526265 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 142.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SK-BR-3: 48.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021554, HPA050569" Enhanced Enhanced Nucleoplasm NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA021554: AB_1858937, HPA050569: AB_2681179" "unprognostic (7.97e-2)" "unprognostic (3.53e-1)" "unprognostic (2.26e-1)" "unprognostic (6.67e-2)" "unprognostic (9.28e-2)" "unprognostic (8.97e-3)" "unprognostic (1.29e-2)" "unprognostic (1.87e-1)" "unprognostic (1.13e-1)" "unprognostic (4.86e-1)" "unprognostic (3.66e-2)" "unprognostic (2.15e-1)" "prognostic favorable (3.52e-4)" "unprognostic (4.65e-3)" "unprognostic (2.40e-1)" "unprognostic (7.15e-2)" "unprognostic (2.63e-2)" 7.9 7.9 4.1 4.8 5.2 23.7 8.2 12.1 4.4 8.7 3.9 6.9 2.0 11.2 6.1 3.7 11.8 7.4 7.5 3.3 5.1 10.2 18.5 6.2 5.3 4.9 4.4 12.7 14.0 7.1 3.5 17.8 5.0 14.1 7.8 7.3 7.6 6.3 5.4 1.9 2.2 8.9 4.3 7.0 4.6 11.2 4.7 8.6 10.1 8.0 3.4 5.5 3.3 5.7 0.0 4.2 21.1 10.7 9.1 6.9 28.5 3.9 0.0 3.0 3.0 9.2 3.4 12.7 11.0 5.8 9.2 0.9 16.7 5.3 3.5 0.0 26.8 6.5 2.8 7.3 5.3 2.2 2.9 6.5 4.6 3.7 10.6 2.5 7.7 10.5 5.9 24.2 2.5 6.7 12.6 5.5 5.3 1.3 6.6 14.7 11.1 4.5 8.4 12.5 12.6 14.6 5.2 48.5 14.8 23.6 9.4 9.1 9.9 7.3 13.5 0.1 3.6 7.0 3.7 14.0 2.8 0.0 9.1 0.1 0.0 0.0 0.2 0.0 0.2 0.2 0.2 0.2 0.1 0.4 0.3 0.3 0.0 0.5 0.2 0.9 0.0 0.0 4.1 5.2 12.1 4.4 3.3 5.1 4.9 4.4 5.0 4.3 4.7 5.7 37.1 25.6 17.0 18.9 55.3 28.4 21.1 8.1 44.3 13.4 48.8 39.8 36.1 25.8 11.8 12.9 16.7 38.3 34.1 38.9 3.9 13.1 83.7 82.4 60.6 34.5 60.4 3.0 12.8 6.9 41.0 29.3 40.8 142.6 9.5 37.0 16.8 31.7 13.3 32.0 11.1 43.0 20.3 21.3 79.6 29.7 19.3 32.0 49.8 13.1 11.2 20.8 8.2 19.6 13.4 8.3 14.8 21.1 24.5 82.1 0.4 14.5 19.4 10.6 26.3 46.6 49.5 14.6 10.6 13.6 12.6 105.2 28.4 19.6 34.7 19.6 ZBTB45 "FLJ14486, ZNF499" ENSG00000119574 "Zinc finger and BTB domain containing 45" Q96K62 19 58513530-58538911 "Predicted intracellular proteins, Transcription factors" "Neurogenesis, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEK 293: 55.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035754, HPA075485" Uncertain Approved "Nuclear bodies,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol "Nuclear bodies" "HPA035754: AB_10603461, HPA075485: " "unprognostic (1.38e-1)" "unprognostic (7.12e-2)" "unprognostic (2.31e-1)" "unprognostic (7.34e-2)" "unprognostic (2.60e-1)" "unprognostic (4.50e-2)" "unprognostic (2.76e-3)" "unprognostic (2.19e-2)" "unprognostic (2.63e-2)" "unprognostic (3.02e-1)" "unprognostic (1.79e-2)" "unprognostic (1.22e-1)" "prognostic favorable (5.38e-4)" "unprognostic (2.08e-1)" "unprognostic (1.06e-1)" "unprognostic (5.47e-2)" "unprognostic (1.40e-1)" 7.9 8.5 6.5 5.1 6.7 4.9 8.6 5.2 11.4 9.9 1.9 10.3 6.1 12.0 1.1 10.1 9.5 3.1 9.1 7.1 4.9 7.7 6.9 6.1 4.2 8.9 6.4 9.3 8.2 4.2 7.1 3.1 8.3 9.5 1.6 2.1 9.0 4.1 10.3 12.7 7.6 2.4 4.5 8.0 8.3 4.9 6.7 3.3 8.3 3.0 2.3 10.5 9.0 7.4 21.3 29.7 7.6 11.7 7.7 6.6 9.6 11.8 4.8 3.0 2.9 5.8 13.4 31.9 15.6 6.6 8.4 13.2 4.2 10.7 1.1 21.4 55.3 17.3 15.1 7.1 4.9 11.1 11.1 6.3 7.4 4.7 3.9 5.6 6.2 32.1 16.0 1.8 4.6 14.2 17.4 11.6 10.6 12.5 26.1 13.8 4.7 19.4 6.2 19.4 23.4 16.7 8.7 22.5 6.1 4.6 33.4 7.6 13.1 12.9 5.6 4.3 11.7 34.8 27.2 15.9 14.7 4.6 8.4 5.8 5.0 10.2 5.7 7.6 6.8 4.4 3.9 5.3 5.3 5.0 4.6 3.4 4.4 5.5 9.1 6.4 3.7 4.7 6.5 6.7 5.2 11.4 7.1 4.9 8.9 6.4 8.3 4.5 6.7 7.4 3.3 9.6 0.5 2.9 5.6 1.7 3.7 5.5 2.2 4.2 4.5 4.6 3.3 1.5 4.0 12.9 0.0 8.9 5.1 6.3 5.9 10.6 0.6 3.4 4.6 5.0 10.3 7.4 1.9 8.9 8.0 3.9 8.6 3.8 0.0 5.6 8.6 4.5 6.6 6.7 2.0 4.6 8.2 6.8 2.4 1.3 5.9 3.7 7.2 0.0 12.3 3.7 7.2 1.5 1.6 8.8 2.6 9.8 3.6 3.8 5.9 5.6 3.8 3.0 13.1 2.5 5.1 5.2 5.9 3.5 2.7 5.6 3.1 4.8 6.0 2.6 ZDHHC3 "DHHC3, GODZ, ZNF373" ENSG00000163812 "Zinc finger DHHC-type palmitoyltransferase 3" Q9NYG2 3 44915257-44976185 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 8 "Early spermatids: 570.7;Late spermatids: 1564.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012465, HPA016616" Approved Approved "Golgi apparatus" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 32: U-937 - Innate immune response" "Cluster 31: Spermatids - Spermatogenesis" "Golgi apparatus" "CAB012465: , HPA016616: AB_1859004" "unprognostic (2.80e-1)" "unprognostic (6.07e-2)" "prognostic favorable (3.43e-4)" "unprognostic (3.10e-2)" "unprognostic (2.47e-2)" "unprognostic (3.38e-1)" "prognostic unfavorable (1.37e-4)" "unprognostic (4.20e-2)" "unprognostic (1.04e-1)" "unprognostic (6.37e-2)" "unprognostic (1.22e-3)" "unprognostic (1.24e-1)" "prognostic favorable (1.81e-8)" "unprognostic (2.64e-1)" "unprognostic (1.49e-1)" "unprognostic (5.33e-2)" "unprognostic (4.26e-2)" 50.1 48.6 23.0 25.7 21.5 82.8 36.3 27.9 22.9 42.2 25.8 70.6 44.1 35.4 24.5 58.0 27.5 32.0 36.3 25.8 21.1 40.3 32.3 41.9 21.9 28.7 25.1 28.9 22.2 46.0 13.4 28.7 29.8 35.6 64.6 16.6 33.3 40.1 43.7 70.0 58.1 36.3 25.8 29.6 55.3 80.8 27.0 26.9 38.6 52.8 33.3 53.6 42.5 25.3 62.5 53.3 41.0 49.1 219.2 100.5 46.8 58.8 80.7 78.3 66.5 61.0 85.1 58.7 31.4 107.9 52.8 80.7 68.4 104.3 74.6 61.7 29.3 55.9 57.9 45.7 50.6 136.3 43.0 92.5 111.6 73.6 67.2 59.8 79.6 63.8 73.8 51.3 78.1 42.9 46.2 73.6 60.7 155.9 96.7 29.9 40.6 47.0 66.7 176.7 14.6 52.8 70.3 70.5 36.4 70.4 57.4 88.2 78.0 55.4 55.2 60.2 66.3 32.2 66.6 59.6 55.2 198.9 39.4 53.7 24.5 32.6 14.6 12.3 13.3 10.7 11.0 16.1 26.8 12.6 10.2 14.4 25.4 14.5 17.5 15.3 17.1 13.6 23.0 21.5 27.9 22.9 25.8 21.1 28.7 25.1 29.8 25.8 27.0 25.3 41.5 41.7 82.1 7.5 17.8 48.2 42.1 40.8 48.9 9.8 24.4 20.8 29.2 24.3 27.1 53.3 6.2 47.7 23.4 105.6 72.4 46.6 570.7 18.8 31.2 34.1 35.9 68.8 15.7 79.0 59.4 26.4 69.3 26.6 19.0 21.5 35.7 29.4 49.5 15.2 15.6 78.2 38.7 34.0 26.7 1564.3 51.9 37.4 24.9 18.7 35.6 25.1 34.0 15.1 11.2 115.8 73.1 44.8 26.2 73.7 112.9 30.1 20.9 10.6 19.7 15.6 31.9 104.5 45.3 70.5 60.2 101.7 25.0 26.1 72.8 128.9 ZFAND4 "ANUBL1, FLJ40185" ENSG00000172671 "Zinc finger AN1-type containing 4" Q86XD8 10 45615500-45672780 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in all" 8 "testis: 37.4" "Group enriched" "Detected in many" 6 "Early spermatids: 414.6;Late spermatids: 689.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 4 "Daudi: 34.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA057543, HPA074103" Enhanced Approved "Golgi apparatus" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 83: Testis - Spermatogenesis" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 25: Spermatids - Spermatogenesis" "Golgi apparatus" "HPA057543: AB_2683461, HPA074103: " "unprognostic (1.57e-1)" "unprognostic (1.53e-2)" "unprognostic (6.90e-2)" "unprognostic (3.57e-2)" "unprognostic (2.27e-2)" "unprognostic (5.31e-2)" "unprognostic (1.62e-1)" "unprognostic (1.46e-3)" "unprognostic (2.55e-1)" "unprognostic (3.16e-1)" "unprognostic (8.85e-5)" "unprognostic (3.23e-1)" "unprognostic (9.15e-3)" "unprognostic (1.18e-1)" "unprognostic (6.19e-2)" "unprognostic (1.28e-1)" "unprognostic (4.07e-3)" 2.2 3.3 1.8 2.0 1.9 2.2 3.0 4.0 2.1 2.6 1.9 2.1 2.1 2.4 1.5 1.6 2.7 1.4 2.5 1.5 2.4 2.1 3.8 2.2 4.9 2.3 2.4 2.4 2.4 1.4 3.0 1.2 2.3 2.6 2.2 2.2 2.3 1.7 2.2 3.2 2.0 1.8 2.1 2.5 1.9 37.4 2.3 3.2 3.4 1.6 4.7 2.1 2.2 2.4 1.0 0.7 1.4 2.1 3.2 2.5 0.0 1.4 2.4 1.3 1.4 0.0 1.0 34.6 1.7 0.9 1.9 0.3 1.1 0.9 1.6 5.6 1.7 1.0 1.1 0.8 2.4 0.0 6.8 2.2 1.7 0.5 1.3 1.0 1.2 4.5 0.9 5.8 1.5 0.1 3.3 0.7 1.4 1.1 0.9 0.5 1.1 0.0 1.1 0.9 2.7 1.8 1.1 1.3 1.1 1.5 2.9 1.9 1.1 0.5 2.5 2.1 1.7 4.6 8.2 0.0 1.0 3.4 0.6 0.3 0.2 0.0 0.4 0.1 0.5 0.4 0.3 0.3 0.1 0.3 0.3 0.4 0.0 0.7 0.4 0.1 0.3 0.1 1.8 1.9 4.0 2.1 1.5 2.4 2.3 2.4 2.3 2.1 2.3 2.4 2.5 6.4 3.1 22.5 7.6 0.8 3.3 1.0 5.7 7.9 4.0 2.2 3.9 4.3 0.7 1.8 27.1 0.3 7.1 3.7 1.9 1.1 414.6 6.5 3.4 2.8 1.8 5.7 3.3 1.8 0.4 3.1 4.6 1.8 2.5 3.0 3.3 5.6 2.2 3.3 23.2 2.5 0.0 2.5 1.0 689.8 6.5 2.3 3.6 13.1 2.2 4.1 1.0 47.3 39.7 1.3 0.5 3.0 10.3 3.9 1.6 3.7 8.9 8.7 6.6 4.5 2.2 86.3 13.5 3.2 2.3 0.1 7.0 4.0 2.7 1.9 ZNF117 "H-plk, HPF9" ENSG00000152926 "Zinc finger protein 117" Q03924 7 64971772-65006684 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 43.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 2.4" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AN3-CA: 21.0;SuSa: 21.9;THP-1: 21.9" HPA031148 Approved "Nucleoli fibrillar center,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 52: Non-specific - Transcription" "Nucleoli fibrillar center, Cytosol" "HPA031148: AB_2673759" "unprognostic (1.04e-1)" "unprognostic (3.04e-2)" "unprognostic (1.68e-1)" "unprognostic (1.06e-1)" "unprognostic (3.44e-2)" "unprognostic (4.35e-2)" "unprognostic (1.45e-2)" "unprognostic (1.24e-1)" "unprognostic (6.13e-2)" "unprognostic (2.30e-1)" "unprognostic (3.35e-1)" "unprognostic (7.10e-2)" "prognostic unfavorable (2.17e-11)" "unprognostic (1.08e-1)" "unprognostic (9.19e-2)" "unprognostic (1.49e-2)" "unprognostic (1.21e-1)" 20.6 28.1 3.8 7.1 3.0 5.4 17.0 3.2 4.5 13.1 4.3 6.8 2.2 8.3 11.2 12.0 8.2 10.2 7.6 3.2 3.7 6.8 3.5 10.8 6.0 4.4 4.3 10.6 5.2 3.7 9.3 10.1 3.1 7.6 4.7 11.8 7.8 4.9 2.8 8.2 4.9 5.7 3.2 8.9 4.6 12.3 3.7 4.7 8.5 1.4 5.6 6.7 11.6 4.1 1.7 0.1 20.0 21.0 7.4 3.4 11.2 4.4 1.0 1.1 2.1 0.9 8.6 7.6 3.6 2.2 3.2 1.3 2.3 0.5 2.4 2.3 2.0 3.5 0.5 4.2 0.6 0.0 2.0 4.3 0.8 0.8 0.8 8.0 3.4 8.8 14.4 5.1 5.0 3.8 8.0 7.9 8.4 2.5 0.3 10.4 1.3 1.5 2.7 3.3 3.1 16.9 2.2 0.9 0.9 21.9 3.8 21.9 10.2 6.0 0.7 3.6 2.8 3.4 6.7 3.9 2.2 9.7 3.7 0.2 0.2 0.3 0.2 0.7 0.2 0.3 0.1 0.1 0.2 0.3 0.1 0.1 2.4 0.3 0.2 0.2 0.1 0.1 3.8 3.0 3.2 4.5 3.2 3.7 4.4 4.3 3.1 3.2 3.7 4.1 10.3 3.2 43.0 35.6 4.2 3.3 5.8 6.2 0.6 14.3 15.5 10.7 7.3 12.8 23.2 5.5 0.0 5.4 5.4 3.3 11.7 10.9 3.1 7.5 10.4 10.9 5.3 2.1 11.4 28.5 2.5 9.6 3.1 8.9 10.8 21.1 17.5 4.2 6.6 28.6 11.6 4.1 10.2 7.9 7.5 3.1 8.7 11.8 5.4 9.4 4.1 7.1 7.2 19.6 7.2 17.7 1.7 5.3 2.3 4.6 1.6 3.3 20.2 7.7 6.6 7.1 7.9 7.2 8.4 3.2 4.7 11.1 3.8 10.3 2.4 12.3 ZNF16 KOX9 ENSG00000170631 "Zinc finger protein 16" P17020 8 144930358-144950888 "Predicted intracellular proteins, Transcription factors" "Cell cycle, Cell division, Transcription, Transcription regulation" "Activator, DNA-binding, Mitogen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 25.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035782, HPA061835" Uncertain Supported Nucleoplasm,Nucleoli NA NA "Cluster 15: NK-cells - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 52: Non-specific - Transcription" Nucleoli Nucleoplasm "HPA035782: AB_10603243, HPA061835: AB_2684621" "unprognostic (4.11e-2)" "unprognostic (1.51e-2)" "unprognostic (6.87e-2)" "unprognostic (2.45e-1)" "unprognostic (2.69e-1)" "prognostic favorable (2.39e-4)" "unprognostic (7.53e-3)" "unprognostic (1.10e-1)" "unprognostic (1.24e-1)" "unprognostic (8.50e-2)" "unprognostic (1.45e-1)" "unprognostic (2.21e-1)" "unprognostic (8.59e-2)" "unprognostic (1.70e-2)" "unprognostic (2.96e-1)" "unprognostic (9.75e-2)" "unprognostic (4.17e-3)" 4.6 3.6 4.6 2.4 4.7 2.6 6.3 4.4 5.0 6.0 5.9 6.5 4.7 6.2 6.9 5.9 7.1 5.7 4.4 4.5 4.4 5.3 3.9 3.7 3.2 4.2 4.2 11.0 7.5 8.6 4.0 3.9 4.3 5.4 4.7 5.1 4.6 5.6 8.3 9.3 4.8 5.5 4.5 3.4 5.0 7.5 4.8 4.4 7.0 8.3 3.9 5.7 6.0 4.6 4.5 3.9 7.7 4.2 6.4 9.0 5.5 4.0 8.9 8.0 7.2 3.1 4.5 7.1 5.2 5.2 4.3 3.5 5.4 8.9 7.2 3.1 4.5 8.2 4.4 4.5 10.7 3.0 4.6 10.9 8.8 5.1 13.2 7.9 4.4 5.3 5.7 4.7 6.4 6.2 6.1 3.0 4.7 6.9 8.8 7.5 4.5 4.5 6.8 6.7 6.4 4.7 8.5 5.1 6.9 5.8 9.5 5.6 4.7 3.6 7.5 4.3 4.5 3.4 3.1 6.4 4.1 4.0 5.8 2.6 3.0 2.2 4.9 2.9 5.6 2.8 3.8 4.5 4.8 4.4 3.8 3.5 0.4 9.2 3.0 2.5 5.8 3.2 4.6 4.7 4.4 5.0 4.5 4.4 4.2 4.2 4.3 4.5 4.8 4.6 3.6 3.2 4.4 4.9 3.4 2.7 6.9 6.8 5.2 11.4 4.3 2.9 3.7 5.7 3.1 9.2 12.5 5.9 7.0 3.2 1.9 7.3 10.3 2.0 3.5 3.7 4.2 3.0 6.8 4.4 3.6 3.8 5.1 3.9 7.0 9.4 5.0 4.5 3.6 6.7 6.3 5.6 6.1 3.5 2.4 3.7 6.2 2.1 1.8 6.5 5.4 6.2 7.2 6.6 7.2 3.6 4.9 6.4 3.2 4.2 10.6 4.8 3.4 25.1 0.0 3.4 4.0 13.6 18.1 4.5 4.5 5.5 5.1 6.6 5.4 5.5 ZNF366 FLJ39796 ENSG00000178175 "Zinc finger protein 366" Q8N895 5 72439903-72507410 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 19.0;Cone photoreceptor cells: 31.3;Endothelial cells: 18.3;Langerhans cells: 9.3;Microglial cells: 54.4;monocytes: 14.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "myeloid DC: 10.4" "Lineage enriched" "Detected in many" 9 "dendritic cells: 10.4" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 1.3;TIME: 1.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA023128, HPA023526, HPA074074" Uncertain Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "Plasma membrane" "HPA023128: AB_1859223, HPA023526: AB_1859224, HPA074074: " "unprognostic (3.49e-1)" "unprognostic (8.44e-2)" "unprognostic (2.44e-1)" "unprognostic (2.27e-1)" "unprognostic (6.17e-2)" "unprognostic (1.95e-3)" "unprognostic (9.25e-2)" "unprognostic (6.67e-2)" "unprognostic (1.43e-1)" "unprognostic (2.47e-1)" "unprognostic (1.34e-1)" "unprognostic (1.27e-1)" "unprognostic (1.88e-3)" "unprognostic (1.53e-1)" "unprognostic (1.61e-1)" "unprognostic (1.43e-1)" "unprognostic (6.29e-2)" 5.8 0.8 6.1 3.4 5.0 0.1 3.2 4.5 5.6 2.8 2.4 1.4 1.5 3.1 0.7 1.8 2.4 2.3 3.8 4.1 4.6 2.1 1.0 2.6 5.0 5.8 5.5 0.8 0.7 1.1 0.4 8.9 6.0 0.9 1.5 0.5 0.8 1.5 5.0 2.2 1.9 3.9 4.1 6.4 1.4 0.5 7.1 3.1 2.2 5.6 4.0 1.7 1.0 4.5 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.5 6.1 5.0 4.5 5.6 4.1 4.6 5.8 5.5 6.0 4.1 7.1 4.5 19.0 0.0 0.6 0.0 0.1 0.5 0.4 0.0 0.6 0.4 0.1 0.3 1.6 0.0 0.6 0.0 31.3 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 18.3 0.0 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 6.8 0.4 0.5 0.0 0.3 0.0 0.0 4.6 9.3 0.5 0.3 2.4 0.0 54.4 14.5 0.1 0.0 0.5 0.3 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.8 0.0 1.2 0.7 0.0 0.0 0.2 0.3 0.1 0.3 0.1 0.0 0.0 ZNF398 "KIAA1339, P51, P71, ZER6" ENSG00000197024 "Zinc finger protein 398" Q8TD17 7 149126416-149183042 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 32.3;Inhibitory neurons: 31.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "NTERA-2: 47.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073151 Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 5: NTERA-2 - Transcription" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Nuclear membrane" "HPA073151: " "unprognostic (4.11e-1)" "unprognostic (8.56e-2)" "unprognostic (3.90e-2)" "unprognostic (1.47e-1)" "unprognostic (1.21e-1)" "unprognostic (6.65e-3)" "unprognostic (2.94e-3)" "unprognostic (2.27e-2)" "unprognostic (3.64e-3)" "unprognostic (1.43e-1)" "unprognostic (7.52e-2)" "unprognostic (2.75e-2)" "unprognostic (1.45e-1)" "unprognostic (3.97e-2)" "unprognostic (9.27e-2)" "unprognostic (9.17e-2)" "unprognostic (1.89e-1)" 3.9 3.3 1.6 3.6 1.8 7.6 4.4 6.3 3.7 4.9 0.6 4.4 3.7 4.1 4.3 6.4 4.3 3.0 3.3 1.6 2.2 3.5 3.6 3.8 4.7 0.1 0.4 4.4 4.5 5.0 4.9 3.8 0.2 4.8 3.6 7.6 4.8 5.1 4.4 6.8 3.7 4.0 0.0 4.5 4.5 8.5 1.8 5.3 3.6 4.5 5.6 4.8 5.0 2.5 9.8 9.5 7.1 13.8 10.4 7.4 8.4 5.8 8.6 7.3 8.2 7.9 5.0 12.5 6.8 10.6 6.5 8.0 12.0 8.2 5.3 7.3 14.4 8.3 7.2 5.3 7.3 9.8 8.1 8.3 12.1 8.2 8.4 5.4 5.2 4.9 11.9 4.7 8.3 13.9 13.6 10.3 47.1 9.4 8.9 10.3 7.9 9.1 5.7 19.0 9.8 10.9 9.2 11.2 5.7 7.7 6.8 10.6 6.2 7.4 1.9 13.3 7.6 12.7 6.6 9.6 9.6 8.0 7.4 2.4 0.6 2.3 1.1 0.7 1.4 1.0 0.8 1.2 0.5 0.8 1.2 1.3 1.2 0.7 0.6 0.7 1.1 0.4 1.6 1.8 6.3 3.7 1.6 2.2 0.1 0.4 0.2 0.0 1.8 2.5 3.9 6.4 4.6 19.2 6.6 7.8 4.5 4.0 5.7 8.8 5.6 3.7 5.9 0.0 5.5 5.5 6.2 4.2 7.7 4.4 0.0 3.9 23.5 7.0 8.6 5.9 1.8 8.6 32.3 2.8 4.9 5.1 12.2 7.5 4.5 7.1 3.9 2.8 3.7 3.3 31.3 3.7 2.0 5.0 3.3 25.2 7.2 3.9 8.8 21.5 4.8 4.5 3.1 20.6 28.6 4.6 2.1 9.1 10.9 6.6 3.8 3.1 6.9 11.6 0.0 6.4 4.5 21.4 13.5 10.1 8.5 3.1 5.2 4.7 3.8 9.9 ZNF543 DKFZp434H055 ENSG00000178229 "Zinc finger protein 543" Q08ER8 19 57320472-57330770 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 12.5;Late spermatids: 15.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA046330 Approved Nucleoplasm NA NA "Cluster 10: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 34: Spermatids - Unknown function" Nucleoplasm "HPA046330: " "unprognostic (9.20e-2)" "unprognostic (8.89e-2)" "unprognostic (2.60e-2)" "unprognostic (1.51e-1)" "unprognostic (1.45e-1)" "unprognostic (4.71e-1)" "unprognostic (2.45e-2)" "unprognostic (9.86e-2)" "unprognostic (1.01e-1)" "unprognostic (6.55e-2)" "unprognostic (2.44e-2)" "unprognostic (7.47e-2)" "prognostic favorable (2.03e-5)" "unprognostic (1.94e-1)" "unprognostic (1.10e-1)" "unprognostic (2.05e-1)" "unprognostic (2.84e-2)" 1.6 1.5 1.9 1.4 1.7 1.8 2.6 4.9 2.0 1.7 0.2 1.4 0.7 1.9 1.6 2.0 2.2 1.5 1.4 1.4 2.2 1.6 1.1 1.7 2.4 1.2 1.6 4.8 1.9 3.1 1.8 2.8 1.4 2.0 1.0 2.7 1.7 2.2 1.8 2.4 1.1 1.9 0.8 2.5 1.6 3.2 1.7 3.2 2.6 1.9 2.4 1.5 1.3 2.0 2.3 3.0 2.8 4.4 2.4 2.1 3.3 1.3 2.4 2.5 4.4 0.9 1.3 3.6 1.8 1.9 1.6 1.3 2.4 2.5 3.3 1.6 6.5 3.5 3.4 2.8 2.6 3.5 2.3 2.3 2.6 1.9 4.1 2.1 1.9 4.2 1.9 0.7 1.8 0.3 4.0 1.1 2.5 0.2 2.3 3.8 4.1 3.9 1.6 5.6 5.1 3.6 3.9 1.5 2.6 2.4 1.8 3.2 1.8 3.6 2.5 0.7 2.5 5.3 3.8 4.1 1.8 1.5 1.9 0.9 1.4 3.1 1.5 1.4 1.8 2.3 1.6 2.2 1.5 2.3 1.9 1.9 1.5 2.1 1.5 1.0 0.9 1.5 1.9 1.7 4.9 2.0 1.4 2.2 1.2 1.6 1.4 0.8 1.7 2.0 4.1 3.2 0.5 0.7 4.2 2.7 1.3 1.9 3.4 4.5 2.3 1.3 1.9 5.7 2.4 0.0 6.2 3.1 4.8 0.5 5.9 1.6 12.5 3.5 2.4 3.8 0.0 1.3 4.4 0.4 1.5 1.7 0.5 4.4 2.5 4.9 2.9 0.8 1.7 6.7 5.3 1.3 8.2 1.6 1.2 15.2 1.5 1.3 1.8 5.6 0.2 3.8 0.0 4.0 2.5 0.2 0.3 2.2 3.2 1.9 0.6 0.9 0.5 6.3 6.6 2.4 2.9 3.3 2.4 4.4 2.6 2.2 2.6 3.3 1.3 1.5 ZNF574 FLJ22059 ENSG00000105732 "Zinc finger protein 574" Q6ZN55 19 42068477-42081552 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 40.9;Spermatocytes: 35.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023196, HPA057274" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 71: Testis - DNA repair" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Transcription" Nucleoplasm Vesicles "HPA023196: AB_2671105, HPA057274: AB_2683392" "unprognostic (3.90e-1)" "unprognostic (3.68e-2)" "unprognostic (3.39e-2)" "unprognostic (7.84e-2)" "unprognostic (1.66e-1)" "unprognostic (2.11e-2)" "unprognostic (9.49e-2)" "unprognostic (2.84e-2)" "unprognostic (5.24e-2)" "unprognostic (1.55e-3)" "unprognostic (6.36e-3)" "unprognostic (2.11e-1)" "unprognostic (2.10e-2)" "unprognostic (6.48e-2)" "unprognostic (3.51e-2)" "unprognostic (2.97e-1)" "unprognostic (1.09e-3)" 8.1 5.4 6.8 4.6 6.1 11.1 7.9 9.5 7.7 8.4 4.3 9.5 6.7 10.3 2.7 9.6 8.8 5.1 6.8 6.2 6.2 5.5 5.4 5.6 6.5 6.9 5.8 9.6 7.9 6.1 6.5 5.0 5.8 7.5 2.8 4.1 8.1 6.7 9.3 12.8 7.5 3.7 5.6 8.4 7.2 27.1 6.3 6.3 6.0 6.4 4.2 8.2 7.5 6.3 15.0 41.1 9.0 11.4 8.1 8.0 9.7 11.0 9.6 14.2 13.6 16.2 10.1 21.4 9.7 9.1 7.5 8.9 10.4 14.1 5.6 11.4 17.6 20.5 10.1 14.0 8.6 12.6 13.5 9.5 13.9 13.2 11.1 8.7 7.9 11.8 17.1 13.3 10.1 31.2 15.2 10.9 16.1 13.5 16.2 20.7 8.6 9.3 7.4 19.7 14.9 12.8 11.3 24.0 7.3 6.2 11.0 20.5 9.5 19.2 14.9 5.8 16.4 14.3 9.3 15.7 10.6 11.9 11.0 12.3 10.5 16.7 16.2 7.8 17.6 17.3 12.1 17.8 12.5 12.8 12.6 11.9 13.3 10.9 11.2 11.1 10.3 12.9 6.8 6.1 9.5 7.7 6.2 6.2 6.9 5.8 5.8 5.6 6.3 6.3 6.0 0.0 3.3 1.3 11.3 29.3 15.1 6.1 40.9 7.5 11.0 7.6 4.3 4.3 6.0 1.8 2.1 7.9 6.3 5.8 1.9 6.9 25.3 6.1 5.7 7.6 3.5 8.6 1.4 5.1 6.7 6.6 7.7 5.7 12.7 5.4 6.8 3.1 5.1 3.3 1.7 7.6 6.1 2.5 11.0 15.7 5.6 3.0 8.8 1.0 7.5 3.9 4.1 1.5 0.9 4.3 8.5 8.6 8.1 10.6 6.4 4.3 5.2 9.8 6.6 8.8 8.0 35.5 20.5 22.1 22.7 4.8 10.6 3.8 7.9 9.6 ZNF584 FLJ39899 ENSG00000171574 "Zinc finger protein 584" Q8IVC4 19 58401504-58418327 "Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HEK 293: 49.8" "Low region specificity" "Detected in all" "HPA043408, HPA048075" Uncertain Approved "Nuclear speckles" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nuclear speckles" "HPA043408: AB_2678466, HPA048075: AB_2680251" "unprognostic (6.06e-2)" "unprognostic (3.27e-3)" "unprognostic (3.76e-3)" "unprognostic (8.15e-3)" "unprognostic (5.50e-2)" "unprognostic (1.16e-2)" "unprognostic (1.23e-1)" "unprognostic (1.04e-2)" "unprognostic (6.33e-2)" "unprognostic (2.17e-1)" "unprognostic (1.01e-3)" "unprognostic (1.90e-3)" "unprognostic (1.66e-1)" "unprognostic (1.53e-1)" "unprognostic (1.80e-1)" "unprognostic (3.27e-1)" "unprognostic (1.36e-2)" 5.7 6.7 4.6 2.9 4.5 1.8 5.0 5.4 5.5 5.6 6.0 6.6 3.5 6.9 3.8 5.8 6.8 2.3 8.9 5.1 4.3 5.3 6.6 4.3 2.5 5.3 4.6 6.1 4.9 8.4 6.7 2.7 4.6 5.0 2.6 5.1 4.7 5.7 9.8 9.0 3.5 5.1 4.0 3.3 5.6 4.7 4.5 3.2 4.7 10.9 3.4 6.1 5.0 4.1 11.7 16.7 11.2 14.7 10.8 10.7 4.5 8.9 15.8 5.4 6.7 2.7 3.5 5.8 7.0 14.7 14.2 6.5 12.1 14.6 6.1 7.5 49.8 15.7 9.6 3.5 18.3 17.3 4.3 11.1 10.4 16.5 22.8 11.9 10.9 9.5 15.8 5.4 8.9 8.3 14.4 5.4 2.8 7.6 23.2 10.4 8.4 9.0 7.6 13.7 9.0 9.5 19.5 5.6 7.4 2.9 3.7 8.6 7.0 21.2 6.5 8.9 14.3 5.0 9.5 1.3 15.2 6.0 7.1 0.0 2.2 0.8 3.2 2.1 5.2 2.1 4.3 4.5 3.4 3.3 2.3 3.6 0.7 3.2 3.5 2.9 5.1 2.7 4.6 4.5 5.4 5.5 5.1 4.3 5.3 4.6 4.6 4.0 4.5 4.1 4.2 3.2 3.9 1.0 2.3 11.2 3.2 5.6 6.2 4.1 4.8 4.3 12.8 5.7 2.1 9.2 4.2 1.0 5.9 1.6 13.7 5.6 9.6 8.1 6.1 4.6 6.7 9.5 2.0 5.1 1.5 5.6 3.6 1.8 2.5 5.5 6.8 4.7 2.6 3.3 2.2 2.3 4.1 2.4 3.3 7.8 5.3 2.1 1.8 0.0 1.3 6.1 2.1 0.5 1.6 4.9 2.8 6.4 2.6 4.2 2.1 5.5 10.2 9.2 6.6 4.4 6.3 8.1 3.7 4.3 15.9 0.4 4.0 12.3 3.2 2.0 ZNF706 HSPC038 ENSG00000120963 "Zinc finger protein 706" Q9Y5V0 8 101177878-101206193 "Predicted intracellular proteins" "Translation regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 1090.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042793 Approved "Plasma membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Ribosome" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane" "HPA042793: AB_10795710" "unprognostic (2.05e-2)" "unprognostic (3.29e-2)" "unprognostic (2.04e-1)" "prognostic unfavorable (3.12e-5)" "unprognostic (1.60e-1)" "unprognostic (1.26e-1)" "unprognostic (2.48e-3)" "unprognostic (5.22e-2)" "unprognostic (3.19e-2)" "unprognostic (1.21e-2)" "unprognostic (1.35e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (5.90e-11)" "unprognostic (9.65e-2)" "unprognostic (1.59e-1)" "unprognostic (3.57e-1)" "unprognostic (2.17e-2)" 99.5 83.4 85.6 57.3 85.3 76.9 92.6 89.1 114.7 86.7 54.6 93.3 93.3 71.5 90.4 147.2 69.0 69.2 86.0 87.2 72.9 95.9 96.0 81.9 95.5 69.0 72.8 70.2 269.9 69.8 93.9 55.3 69.6 70.9 87.2 46.9 99.1 49.1 110.7 180.0 100.0 50.7 69.7 100.5 92.7 118.1 70.0 67.2 82.3 86.1 102.5 75.1 101.1 83.1 203.0 113.9 196.0 62.7 69.0 78.0 124.8 82.4 105.5 83.5 89.0 81.8 121.5 121.9 139.4 99.1 170.4 108.4 113.3 111.0 95.8 90.5 98.0 122.1 69.5 159.2 90.7 92.2 114.1 69.1 170.9 78.9 170.7 115.1 144.0 121.4 134.8 230.6 75.0 142.6 194.5 252.2 59.7 408.6 278.8 80.8 65.3 251.1 112.7 103.2 129.4 57.6 57.6 95.0 375.9 166.3 99.3 96.5 96.3 45.6 93.9 121.9 87.0 194.1 202.6 197.0 123.5 199.2 215.8 255.1 280.0 162.6 138.0 463.2 143.4 400.0 191.5 178.0 264.1 344.1 214.7 206.3 38.7 130.9 492.1 532.8 302.8 268.7 85.6 85.3 89.1 114.7 87.2 72.9 69.0 72.8 69.6 69.7 70.0 83.1 131.4 60.9 41.0 29.0 188.6 459.7 242.3 252.7 149.7 59.3 159.3 182.6 79.8 137.2 138.1 79.1 18.8 190.6 175.0 288.4 180.0 264.5 439.7 125.5 70.1 137.7 265.1 107.1 31.5 259.8 339.0 131.4 106.5 114.9 122.2 85.1 99.2 123.4 265.3 85.8 21.1 275.3 231.9 162.3 186.4 1090.7 86.9 214.8 206.3 16.9 298.4 131.3 114.4 14.6 57.6 401.5 265.4 86.9 329.4 326.5 339.2 195.1 110.8 55.9 105.2 111.6 169.8 84.3 82.7 224.8 518.0 193.3 112.7 72.7 153.5 311.7 ZNF726 ZNF92P3 ENSG00000213967 "Zinc finger protein 726" A6NNF4 19 23914876-23945159 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Erythroid cells: 9.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 8.2;NK-cell: 3.1" "Group enriched" "Detected in many" 4 "granulocytes: 8.2;NK-cells: 3.1" "Cell line enhanced" "Detected in many" "MOLT-4: 29.6" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 12: Non-specific - Cell cycle regulation" "unprognostic (5.40e-2)" "unprognostic (2.27e-1)" "unprognostic (4.41e-3)" "unprognostic (1.95e-1)" "unprognostic (1.01e-1)" "unprognostic (4.97e-2)" "unprognostic (1.80e-1)" "unprognostic (2.91e-2)" "unprognostic (8.26e-4)" "unprognostic (5.65e-4)" "unprognostic (2.14e-2)" "unprognostic (9.87e-3)" "unprognostic (2.90e-2)" "unprognostic (4.25e-2)" "unprognostic (1.64e-1)" "unprognostic (4.97e-2)" "unprognostic (3.20e-3)" 1.2 1.3 2.5 1.8 1.8 5.8 4.2 3.8 2.3 2.9 0.9 1.9 1.2 2.2 5.1 2.4 1.7 2.1 0.7 2.0 2.6 2.8 2.2 1.6 4.2 1.9 2.2 1.4 0.7 2.1 0.6 3.4 2.2 2.5 3.9 3.2 1.3 2.0 1.6 4.8 1.3 1.0 1.6 2.5 3.0 2.9 3.4 6.1 2.2 1.0 3.4 1.7 2.8 2.5 1.1 1.9 16.3 9.0 1.1 1.1 0.8 4.0 1.4 8.7 8.3 1.4 5.3 0.1 7.5 1.7 6.3 1.2 15.2 0.2 11.8 11.3 8.0 6.6 1.5 0.4 0.6 0.1 3.8 1.2 0.9 5.2 0.3 1.0 0.0 9.5 5.2 0.1 3.3 5.6 29.6 19.8 9.8 0.1 8.4 21.6 12.1 4.8 3.0 6.6 5.4 9.1 0.0 0.1 4.1 7.9 10.5 1.3 1.1 3.1 2.3 13.5 8.5 0.1 9.2 13.1 0.1 2.4 4.5 8.2 0.4 0.2 0.4 0.5 0.2 0.7 1.0 1.0 0.4 1.0 1.0 1.2 0.8 3.1 0.3 1.1 1.2 0.6 2.5 1.8 3.8 2.3 2.0 2.6 1.9 2.2 2.2 1.6 3.4 2.5 0.6 3.2 0.0 2.9 2.4 0.9 1.6 0.2 0.6 3.8 2.4 1.3 4.5 1.5 1.1 3.7 0.0 7.2 2.9 1.5 1.9 1.4 0.1 1.8 2.4 2.2 0.0 9.0 1.0 0.2 6.7 1.8 0.0 2.6 3.8 5.3 1.4 2.0 2.2 5.0 2.4 0.7 2.0 1.9 2.0 0.3 0.3 1.2 0.0 0.0 0.8 0.6 3.1 5.0 2.9 0.6 0.3 1.9 1.4 0.9 0.1 0.5 2.5 1.2 0.0 1.7 1.7 2.3 6.0 2.0 1.7 4.1 2.4 1.8 0.5 1.5 ZNF777 KIAA1285 ENSG00000196453 "Zinc finger protein 777" Q9ULD5 7 149431363-149461062 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003252 Approved Approved Nucleoplasm NA NA "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA003252: AB_1080755" "unprognostic (7.19e-2)" "unprognostic (1.06e-1)" "unprognostic (1.17e-2)" "unprognostic (3.37e-2)" "unprognostic (4.78e-2)" "unprognostic (6.64e-2)" "unprognostic (5.87e-3)" "unprognostic (4.52e-2)" "unprognostic (1.10e-1)" "unprognostic (6.15e-2)" "unprognostic (5.17e-3)" "unprognostic (2.64e-1)" "unprognostic (4.00e-2)" "unprognostic (6.33e-2)" "unprognostic (1.68e-1)" "unprognostic (8.23e-2)" "unprognostic (5.72e-2)" 7.5 6.6 5.9 4.4 5.4 7.9 7.7 5.8 7.0 8.7 2.3 9.0 4.5 10.4 3.3 6.2 8.4 3.6 7.1 6.0 6.3 6.2 7.3 5.3 5.1 5.9 5.3 10.0 7.5 6.4 8.5 4.9 5.1 8.9 3.3 3.4 7.5 5.2 13.9 11.7 6.3 5.2 4.7 6.7 7.3 6.7 5.9 5.7 7.3 7.0 3.9 9.0 7.9 5.5 14.9 18.0 11.9 17.3 8.7 7.0 15.3 9.4 9.9 12.5 10.8 11.3 9.3 9.4 18.5 10.7 7.7 9.7 11.7 14.3 6.8 15.3 17.8 9.2 5.0 11.4 14.7 13.2 12.9 8.3 16.1 10.1 14.6 6.6 6.8 12.4 30.2 0.0 7.2 19.2 27.9 18.0 14.5 6.6 10.5 22.7 6.1 19.8 7.7 11.4 12.9 18.1 16.2 16.5 15.7 4.3 7.8 21.7 10.7 10.4 4.1 20.8 15.5 8.6 8.2 4.4 7.8 9.0 13.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 5.9 5.4 5.8 7.0 6.0 6.3 5.9 5.3 5.1 4.7 5.9 5.5 4.0 0.0 1.7 5.9 3.8 1.1 1.4 0.3 2.8 6.5 3.9 5.5 2.9 2.8 0.1 1.8 6.2 2.0 4.2 3.1 0.0 1.2 2.6 2.9 4.8 2.9 1.8 6.6 6.9 1.0 3.8 2.8 2.0 4.5 0.0 8.2 2.9 5.7 1.6 1.7 6.7 3.1 0.0 2.2 1.3 3.8 2.8 2.0 0.0 4.7 0.2 5.5 2.1 3.0 3.5 1.1 3.1 3.4 1.6 2.4 1.4 1.6 0.8 5.5 0.0 5.2 3.7 1.5 4.6 2.5 1.8 3.8 3.5 6.6 2.8 1.0 ZP1 ENSG00000149506 "Zona pellucida glycoprotein 1" P60852 11 60867562-60875693 "Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Fertilization "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "Early spermatids: 32.3;Late spermatids: 87.6" "Cancer enhanced" "Detected in single" "prostate cancer: 0.6" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 32 "plasmacytoid DC: 3.1" "Lineage enriched" "Detected in single" 32 "dendritic cells: 3.1" "Group enriched" "Detected in some" 40 "RPMI-8226: 12.4;SK-BR-3: 3.3" "Not detected" "Not detected" "Secreted in female reproductive system" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 25: RPMI-8226 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (6.40e-3)" "unprognostic (2.18e-4)" "unprognostic (1.63e-1)" "unprognostic (1.15e-2)" "unprognostic (1.14e-1)" "unprognostic (7.02e-2)" "unprognostic (8.27e-2)" "unprognostic (9.95e-2)" "unprognostic (1.94e-2)" "unprognostic (8.15e-3)" "unprognostic (2.52e-1)" "unprognostic (9.25e-4)" "unprognostic (5.31e-13)" "unprognostic (4.13e-2)" "unprognostic (2.38e-1)" "unprognostic (6.27e-2)" "unprognostic (5.61e-2)" 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.1 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 1.3 0.3 0.0 0.1 0.0 0.0 0.0 1.3 0.1 0.1 0.7 0.0 0.6 0.0 0.0 0.2 0.1 0.0 0.0 0.0 32.3 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 87.6 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 6.6 0.1 5.0 1.9 0.0 0.0 0.1 0.3 0.8 0.0 0.0 0.1 ZWINT "KNTC2AP, SIP30, Zwint1" ENSG00000122952 "ZW10 interacting kinetochore protein" O95229 10 56357227-56361273 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 41.6;lymphoid tissue: 43.5" "Cell type enhanced" "Detected in many" "Erythroid cells: 133.0;Extravillous trophoblasts: 108.6;Late spermatids: 208.8;Spermatocytes: 121.0;Spermatogonia: 100.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 17.0" "Lineage enriched" "Detected in many" 5 "T-cells: 17.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" "HPA005757, HPA022264" Enhanced "Nucleoplasm,Nuclear bodies,Cytosol" No Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nuclear bodies" Cytosol "HPA005757: AB_10600224, HPA022264: AB_10600995" "unprognostic (5.59e-2)" "unprognostic (1.71e-2)" "unprognostic (2.33e-1)" "unprognostic (1.06e-2)" "unprognostic (9.38e-2)" "unprognostic (6.58e-2)" "prognostic unfavorable (1.77e-8)" "unprognostic (6.36e-3)" "unprognostic (5.88e-2)" "unprognostic (1.45e-2)" "unprognostic (1.58e-3)" "unprognostic (1.86e-2)" "prognostic unfavorable (3.72e-12)" "unprognostic (1.40e-2)" "unprognostic (1.48e-1)" "unprognostic (5.47e-2)" "unprognostic (3.46e-1)" 2.6 2.5 1.2 15.7 1.3 41.6 6.5 1.1 1.8 3.9 1.0 18.8 13.7 3.2 1.7 12.4 2.8 2.4 1.5 1.5 1.2 4.4 4.8 2.9 26.5 1.2 1.3 1.5 2.4 5.4 0.8 10.8 1.2 2.5 22.4 0.5 3.3 1.4 0.3 10.8 14.8 6.8 1.2 5.0 12.5 26.1 1.6 43.5 3.9 0.7 33.0 5.0 4.3 1.4 199.8 154.8 107.9 120.9 7.5 10.8 88.1 143.1 108.0 169.6 153.4 275.4 116.1 102.0 53.2 49.6 79.1 99.9 153.2 108.3 156.7 259.9 80.2 101.6 120.8 129.4 0.7 169.6 131.0 5.1 6.8 157.7 64.9 20.8 86.8 134.2 140.2 121.4 151.1 160.1 150.7 108.3 77.0 135.9 188.7 151.7 209.5 54.0 53.5 87.5 99.8 61.2 135.2 304.2 35.3 62.2 197.3 163.4 47.4 73.6 189.4 76.9 223.2 105.8 55.3 176.0 103.8 210.0 94.7 0.0 0.8 0.7 2.4 3.0 0.3 1.6 5.3 3.6 1.4 0.3 6.3 3.6 0.0 3.5 2.3 1.1 17.0 3.1 1.2 1.3 1.1 1.8 1.5 1.2 1.2 1.3 1.2 1.2 1.6 1.4 0.9 3.2 1.7 0.3 11.1 18.4 6.0 20.2 4.6 2.0 9.4 5.5 1.4 2.8 7.3 5.5 0.0 73.7 3.3 17.9 0.0 9.7 74.0 7.0 4.3 5.7 0.0 133.0 1.3 13.3 108.6 10.3 16.8 8.0 0.0 27.6 7.9 3.5 49.4 0.0 0.3 22.8 14.2 8.5 8.8 208.8 5.0 9.2 7.2 0.0 2.6 1.3 0.0 0.0 0.6 8.6 16.4 2.6 42.4 1.9 8.7 6.0 2.5 0.9 0.0 1.4 10.6 121.0 100.3 24.5 8.2 23.1 7.9 6.5 39.4 8.4