Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" ACER2 "ALKCDase2, ASAH3L, FLJ41587" ENSG00000177076 "Alkaline ceramidase 2" Q5QJU3 9 19409009-19452505 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "stomach 1: 61.8;urinary bladder: 39.2" "Cell type enhanced" "Detected in some" "Excitatory neurons: 19.7;Gastric mucus-secreting cells: 21.9;Inhibitory neurons: 10.3;Microglial cells: 26.2;Oligodendrocytes: 7.0" "Cancer enhanced" "Detected in many" "urothelial cancer: 15.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "BEWO: 29.7;RT4: 73.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 4: Stomach - Digestion" "Cluster 15: RT4 - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (1.94e-1)" "unprognostic (2.29e-1)" "unprognostic (2.06e-1)" "unprognostic (2.30e-1)" "unprognostic (1.57e-1)" "unprognostic (1.69e-1)" "unprognostic (1.19e-1)" "unprognostic (3.95e-2)" "unprognostic (2.03e-1)" "unprognostic (3.90e-1)" "unprognostic (1.34e-1)" "unprognostic (1.73e-1)" "unprognostic (2.13e-2)" "unprognostic (1.52e-1)" "unprognostic (1.09e-1)" "unprognostic (7.42e-2)" "unprognostic (8.46e-3)" 6.9 1.4 4.5 1.1 3.4 0.6 5.0 2.7 5.0 1.7 2.0 3.3 4.5 1.4 4.2 2.2 3.7 1.7 2.9 4.4 3.1 1.9 2.4 2.2 1.0 3.2 3.1 1.0 6.8 2.5 1.1 9.7 4.3 3.7 4.3 3.8 1.9 4.5 1.2 5.9 2.7 1.3 2.8 1.4 61.8 1.9 5.9 2.4 2.5 1.0 1.3 39.2 1.7 3.7 1.2 2.0 3.9 2.0 6.2 0.5 29.7 2.1 1.4 0.7 1.0 0.6 1.9 1.3 0.7 0.3 0.4 4.5 0.8 5.8 1.5 2.4 1.1 2.1 1.6 3.0 1.3 0.5 2.0 1.8 5.6 2.2 2.4 0.6 6.2 2.1 3.1 3.8 2.0 1.7 3.6 1.8 3.1 11.1 0.9 3.2 1.0 0.7 0.6 73.6 6.9 1.8 0.4 2.2 0.5 9.3 2.7 2.5 3.1 0.5 1.5 0.6 0.9 1.4 1.7 1.4 0.6 1.5 1.3 0.0 0.0 0.0 0.1 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 4.5 3.4 2.7 5.0 4.4 3.1 3.2 3.1 4.3 2.8 5.9 3.7 3.2 0.0 0.0 1.0 0.7 0.3 0.4 0.1 0.6 1.0 0.3 0.4 0.1 0.0 0.1 0.0 2.1 0.5 0.4 0.0 0.0 0.1 2.6 0.3 0.2 0.8 0.0 0.8 19.7 0.0 0.6 0.3 21.9 0.4 0.0 0.0 1.4 0.0 0.1 0.0 10.3 0.0 0.0 0.0 0.0 4.0 0.3 0.2 0.0 26.2 0.0 0.6 0.0 5.5 7.0 0.1 0.0 0.0 0.4 0.2 0.0 0.1 0.1 0.6 0.0 0.6 0.4 0.4 0.4 0.8 0.0 4.0 0.3 0.0 0.0 1.1 ADGRF5 "DKFZp564O1923, GPR116, KIAA0758" ENSG00000069122 "Adhesion G protein-coupled receptor F5" Q8IZF2 6 46852522-46954943 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 104.5" "Cell type enhanced" "Detected in many" "Adipocytes: 428.1;Alveolar cells type 1: 291.7;Alveolar cells type 2: 539.9;Endothelial cells: 222.6;Hepatic stellate cells: 251.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "HUVEC TERT2: 25.0;TIME: 74.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 55000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (8.45e-2)" "unprognostic (3.00e-3)" "unprognostic (1.13e-1)" "unprognostic (3.26e-1)" "unprognostic (6.51e-2)" "unprognostic (1.89e-2)" "unprognostic (5.76e-2)" "unprognostic (9.00e-3)" "unprognostic (7.80e-2)" "unprognostic (3.32e-1)" "unprognostic (1.42e-1)" "unprognostic (4.56e-2)" "prognostic favorable (8.84e-5)" "unprognostic (1.43e-2)" "unprognostic (5.91e-2)" "unprognostic (2.82e-2)" "unprognostic (3.78e-2)" 69.8 22.8 15.1 6.9 15.0 0.0 46.0 15.0 18.0 10.4 8.6 9.9 5.7 16.0 7.7 7.0 15.0 16.9 51.6 12.8 15.1 58.9 13.0 104.5 8.5 16.6 15.6 6.5 6.4 13.2 6.7 50.6 18.2 8.9 5.7 1.8 5.9 9.2 30.4 7.7 8.5 21.8 13.8 40.5 8.4 3.1 21.6 3.7 32.2 70.2 3.2 11.4 10.0 15.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 74.1 0.0 0.2 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.1 15.0 15.0 18.0 12.8 15.1 16.6 15.6 18.2 13.8 21.6 15.3 428.1 291.7 539.9 2.0 2.9 0.0 0.2 0.0 2.2 0.0 1.5 2.9 16.2 8.6 89.7 1.8 0.0 0.2 1.1 0.6 11.7 0.2 10.6 0.8 1.2 222.6 0.0 0.0 8.4 0.0 1.1 9.0 2.6 0.4 12.6 0.0 251.3 4.0 0.2 0.0 1.0 0.5 0.0 13.7 0.0 4.8 3.1 2.7 0.0 104.0 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 1.2 0.6 0.5 0.2 48.1 0.7 98.6 9.6 80.1 0.2 0.9 0.6 0.0 0.3 1.8 15.5 0.1 0.8 ADORA3 AD026 ENSG00000282608 "Adenosine A3 receptor" P0DMS8 1 111499429-111503633 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 21.8" "Cell type enhanced" "Detected in some" "Hofbauer cells: 17.9;Kupffer cells: 79.2;Late spermatids: 18.2;Macrophages: 26.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 40 "eosinophil: 601.6" "Lineage enriched" "Detected in many" 40 "granulocytes: 601.6" "Cell line enriched" "Detected in some" 9 "HMC-1: 108.1" "Low region specificity" "Detected in many" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" 4.5 15.0 8.9 4.3 9.2 0.2 5.5 10.6 14.6 4.4 8.8 6.6 4.5 1.9 0.2 2.5 3.6 5.8 3.4 8.8 12.3 1.6 3.3 3.5 6.4 16.1 11.1 1.8 1.8 3.1 2.6 2.8 14.9 2.4 5.1 1.0 2.8 2.4 0.5 0.9 9.4 4.8 13.5 4.3 3.0 1.2 16.9 3.5 1.4 1.0 2.7 4.3 1.7 21.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.8 0.0 0.0 0.0 0.0 108.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 12.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 10.0 8.1 601.6 0.0 5.6 0.1 0.2 0.0 0.0 15.0 0.1 0.1 0.1 2.0 0.1 2.1 3.0 0.0 2.5 8.9 9.2 10.6 14.6 8.8 12.3 16.1 11.1 14.9 13.5 16.9 21.8 0.2 0.0 0.0 0.0 1.0 0.3 0.0 0.0 0.0 0.1 0.1 0.6 0.4 0.0 0.0 0.0 0.0 0.1 1.4 0.1 0.0 0.0 7.3 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.0 0.0 1.8 0.2 17.9 0.0 0.0 0.0 0.0 79.2 4.4 18.2 0.3 26.3 0.0 0.0 2.2 0.1 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.7 0.0 0.2 0.0 0.2 0.2 0.4 0.3 0.1 0.4 0.0 1.6 0.0 0.0 0.1 AGR3 "BCMP11, hAG-3, HAG3, PDIA18" ENSG00000173467 "Anterior gradient 3, protein disulphide isomerase family member" Q8TD06 7 16859412-16881987 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 225.2;intestine: 237.6;lung: 152.7" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 861.1;Intestinal goblet cells: 701.9;Paneth cells: 744.5;Proximal enterocytes: 1051.2;Respiratory ciliated cells: 1771.2;Undifferentiated cells: 495.4" "Cancer enhanced" "Detected in many" "breast cancer: 104.5" "Region enhanced" "Detected in some" "midbrain: 3.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 28 "OE19: 109.8;T-47d: 339.3" "Region enriched" "Detected in some" 5 "olfactory bulb: 4.6" HPA053942 Enhanced Supported "Endoplasmic reticulum,Vesicles" "Intracellular and membrane" NA NA 67000 "Cluster 9: Intestine - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "Endoplasmic reticulum" Vesicles "HPA053942: AB_2682317" "unprognostic (2.18e-2)" "unprognostic (2.02e-1)" "unprognostic (2.13e-1)" "unprognostic (9.59e-2)" "unprognostic (3.32e-3)" "unprognostic (3.08e-2)" "unprognostic (1.49e-1)" "unprognostic (1.46e-1)" "unprognostic (7.29e-2)" "unprognostic (1.13e-1)" "unprognostic (8.56e-3)" "unprognostic (2.32e-1)" "unprognostic (2.96e-1)" "unprognostic (6.66e-2)" "unprognostic (1.57e-1)" 0.6 0.1 0.0 11.0 0.0 0.0 69.6 0.0 0.2 25.0 0.1 219.9 167.2 8.7 0.0 1.5 225.2 48.3 0.1 0.1 0.4 2.5 0.3 152.7 0.2 2.0 3.4 0.3 10.7 0.0 21.2 0.8 1.0 4.8 214.9 0.0 30.9 0.8 0.0 1.5 237.6 8.7 0.7 0.3 99.9 0.2 0.2 0.0 7.3 0.0 0.8 27.6 0.2 0.5 0.0 0.6 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.2 109.8 0.0 0.0 0.0 2.3 8.1 0.0 1.3 0.4 0.0 0.6 0.0 0.0 339.3 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.4 2.0 3.4 1.0 0.7 0.2 0.5 0.7 333.3 408.1 0.3 1.4 2.7 12.5 108.5 0.0 0.0 105.1 51.9 0.1 31.5 319.9 29.5 0.0 3.4 0.7 380.0 1.9 30.4 0.0 861.1 7.4 1.9 112.7 0.0 0.2 71.4 3.3 5.3 71.4 39.2 20.8 0.0 0.0 0.0 0.5 0.0 0.2 701.9 134.3 0.0 0.3 0.0 0.3 2.3 0.0 0.0 0.6 0.0 0.0 0.0 0.1 16.6 744.5 0.0 0.4 7.1 1051.2 0.0 1771.2 0.0 0.0 0.0 27.9 0.0 0.1 0.0 9.8 2.2 4.1 0.0 495.4 117.9 AKR1B10 "AKR1B11, AKR1B12, ALDRLn, ARL-1, ARL1, HIS, HSI" ENSG00000198074 "Aldo-keto reductase family 1 member B10" O60218 7 134527567-134541412 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 224.5;intestine: 614.8;stomach 1: 432.5" "Cell type enhanced" "Detected in many" "Cholangiocytes: 193.0;Distal enterocytes: 201.0;Gastric mucus-secreting cells: 542.3;Proximal enterocytes: 327.1" "Cancer enhanced" "Detected in many" "liver cancer: 353.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 104 "A549: 2959.1;Hep G2: 835.6;OE19: 3141.0" "Low region specificity" "Detected in all" "HPA020280, CAB070163, HPA073633" Enhanced Supported "Plasma membrane,Cytosol" "Secreted to digestive system" NA NA 67000000 "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" Cytosol "Plasma membrane" "CAB070163: AB_10008614, HPA020280: AB_10602228, HPA073633: AB_2686620" "unprognostic (1.29e-2)" "unprognostic (1.50e-1)" "prognostic favorable (1.91e-4)" "unprognostic (6.03e-2)" "unprognostic (4.67e-2)" "unprognostic (2.57e-1)" "unprognostic (2.16e-3)" "unprognostic (1.01e-1)" "unprognostic (1.47e-1)" "unprognostic (3.18e-2)" "unprognostic (4.65e-3)" "unprognostic (1.54e-1)" "prognostic unfavorable (4.80e-9)" "unprognostic (2.12e-1)" "unprognostic (2.12e-1)" "unprognostic (1.43e-2)" "unprognostic (1.25e-1)" 0.9 5.5 0.1 7.9 0.0 0.2 0.4 0.3 0.1 73.9 0.0 73.4 614.8 0.5 0.1 224.5 0.9 176.1 0.2 0.1 0.1 12.2 40.0 0.4 0.3 0.0 0.0 0.2 0.7 0.0 4.8 0.1 0.1 1.3 45.6 0.1 32.4 0.2 3.7 7.7 354.8 3.2 0.1 0.1 432.5 0.6 0.0 5.5 0.6 5.9 7.7 65.8 145.6 0.2 0.0 2959.1 0.0 0.0 0.7 2.3 9.0 0.3 1.1 0.2 0.0 5.9 0.9 0.0 1.1 1.6 4.6 6.2 0.0 4.0 0.2 0.1 0.0 0.0 1.9 835.6 0.7 0.0 0.6 0.1 13.8 0.7 0.0 4.0 0.5 0.0 0.0 0.0 0.6 5.4 0.1 1.3 0.5 3141.0 2.3 0.3 0.0 2.7 1.5 2.7 1.0 1.5 1.8 1.3 0.1 0.1 0.0 0.1 1.9 1.2 1.2 0.2 1.0 0.4 0.1 0.0 22.2 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.0 0.0 1.0 2.8 2.1 52.1 3.4 0.0 0.1 0.0 0.7 193.0 13.5 0.0 0.0 0.3 0.0 201.0 0.0 31.5 0.7 2.9 0.1 0.2 3.5 2.7 0.0 27.5 0.1 4.4 542.3 1.0 0.0 0.0 2.2 62.9 0.0 0.0 0.1 29.5 4.1 0.6 0.3 0.7 3.4 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 66.9 42.5 1.9 1.7 1.0 327.1 3.8 4.8 0.0 0.0 3.7 1.5 0.0 0.1 96.0 10.4 0.3 0.5 0.0 73.0 11.4 AMER3 "FAM123C, FLJ38377" ENSG00000178171 "APC membrane recruitment protein 3" Q8N944 2 130755540-130768134 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 14.6" "Cell type enhanced" "Detected in some" "Bipolar cells: 8.2;Enteroendocrine cells: 15.1;Excitatory neurons: 6.6;Horizontal cells: 3.3;Inhibitory neurons: 5.7;Rod photoreceptor cells: 4.9" "Cancer enhanced" "Detected in single" "pancreatic cancer: 0.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "SCLC-21H: 9.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA045593, HPA054230" Uncertain Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 6: Brain - Smell perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Nuclear bodies" "Nucleoplasm, Cytosol" "HPA045593: AB_10965021, HPA054230: AB_2682423" "unprognostic (6.68e-2)" "unprognostic (3.73e-1)" "unprognostic (2.17e-2)" "unprognostic (1.83e-1)" "unprognostic (2.71e-1)" "unprognostic (5.33e-3)" "unprognostic (1.51e-1)" "unprognostic (2.71e-1)" "unprognostic (1.02e-1)" "unprognostic (6.46e-3)" 0.0 0.6 4.0 0.0 4.5 0.1 0.0 14.6 8.1 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 3.7 3.2 0.0 0.0 0.0 0.0 1.2 0.2 0.0 0.9 0.0 2.8 0.0 1.0 0.0 0.1 2.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.3 1.6 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.0 4.5 14.6 8.1 3.7 3.2 1.2 0.2 1.0 0.0 1.6 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.6 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 15.1 0.0 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 5.7 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.9 0.0 0.5 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ANGPTL3 ANGPT5 ENSG00000132855 "Angiopoietin like 3" Q9Y5C1 1 62597520-62606313 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Angiogenesis, Cell adhesion, Lipid metabolism" Heparin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "liver: 675.7" "Group enriched" "Detected in some" 12 "Hepatocytes: 567.6;Proximal tubular cells: 272.5" "Cancer enriched" "Detected in some" 39 "liver cancer: 94.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA038097 Approved "Secreted to blood" NA NA 225000000 120000000 "Cluster 85: Liver - Metabolism" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA038097: AB_10675628" "unprognostic (2.29e-1)" "unprognostic (8.01e-2)" "unprognostic (2.51e-1)" "unprognostic (4.06e-2)" "unprognostic (2.70e-1)" "unprognostic (1.25e-2)" "unprognostic (4.06e-2)" "unprognostic (1.56e-2)" "unprognostic (8.11e-3)" "unprognostic (6.85e-3)" "unprognostic (2.89e-2)" "unprognostic (1.20e-2)" "unprognostic (1.09e-2)" "unprognostic (3.08e-2)" "unprognostic (1.09e-2)" "unprognostic (5.38e-2)" "unprognostic (7.62e-2)" 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 53.0 675.7 0.0 0.0 0.2 0.2 0.1 0.2 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 4.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.3 0.1 0.1 0.1 0.2 0.2 0.1 0.2 0.2 0.4 0.0 0.0 0.0 0.3 2.3 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.3 11.5 0.0 5.5 0.0 0.0 0.0 0.0 33.2 0.0 0.0 0.1 0.1 0.7 0.0 16.0 0.1 0.2 0.1 0.0 2.6 0.3 0.0 0.0 9.7 567.6 0.1 0.0 0.1 0.0 0.0 16.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 272.5 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 1.9 0.1 0.0 0.0 ANLN "ANILLIN, scra, Scraps" ENSG00000011426 "Anillin actin binding protein" Q9NQW6 7 36389821-36453791 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Actin-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 266.0" "Group enriched" "Detected in many" 5 "Early spermatids: 156.4;Oligodendrocytes: 441.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "HBF TERT88: 655.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005680, CAB033902, HPA050556, CAB062547, CAB068175" Enhanced Enhanced Nucleoplasm,Midbody Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 70: Brain - Nervous system development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm Midbody "CAB033902: AB_2058302, CAB062547: AB_2665622, CAB068175: AB_2665623, HPA005680: AB_2667388, HPA050556: AB_2681175" "unprognostic (4.23e-2)" "unprognostic (1.59e-3)" "unprognostic (1.49e-1)" "prognostic unfavorable (1.73e-4)" "unprognostic (1.67e-2)" "unprognostic (3.44e-2)" "prognostic unfavorable (5.97e-7)" "prognostic unfavorable (6.99e-5)" "unprognostic (2.69e-2)" "unprognostic (3.66e-2)" "prognostic unfavorable (2.00e-6)" "unprognostic (3.13e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (5.29e-2)" "unprognostic (1.34e-1)" "unprognostic (2.94e-2)" "unprognostic (4.04e-3)" 1.2 0.7 59.8 5.2 134.5 36.4 2.0 125.1 72.7 1.8 18.4 6.0 4.4 1.8 0.2 10.4 0.9 2.1 0.8 59.3 83.6 0.4 1.2 1.4 6.7 162.3 106.5 0.9 0.6 0.2 0.2 8.9 160.2 0.9 8.0 0.3 1.7 0.4 0.3 13.6 4.3 14.9 99.2 1.2 4.8 12.4 102.3 16.0 0.8 0.3 9.5 3.2 3.2 266.0 476.1 96.5 79.3 61.0 10.7 26.9 85.6 292.5 169.3 344.4 256.0 66.4 142.7 23.9 82.1 148.6 182.8 237.0 63.4 170.7 655.4 16.1 46.0 32.7 104.8 55.8 1.7 47.3 36.7 6.0 7.7 225.3 147.2 40.8 109.3 31.2 69.6 48.8 284.4 71.0 40.0 54.8 88.5 71.9 102.3 29.1 238.2 15.9 76.5 76.5 33.5 39.5 154.1 175.8 26.1 109.6 119.0 53.6 104.5 214.2 239.0 127.6 346.6 20.1 34.2 43.2 72.9 74.9 460.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.3 59.8 134.5 125.1 72.7 59.3 83.6 162.3 106.5 160.2 99.2 102.3 266.0 0.4 0.0 1.1 2.3 1.0 14.1 1.9 8.3 7.4 0.0 1.9 2.0 0.6 0.0 3.2 0.0 0.0 13.8 1.1 2.8 0.0 0.7 156.4 18.9 3.2 1.9 0.0 35.3 3.4 0.2 23.2 6.9 10.2 12.8 0.0 15.4 1.1 0.5 9.8 0.0 5.7 3.4 6.1 1.6 5.9 53.3 1.2 2.7 0.0 0.0 0.0 0.0 0.0 1.5 441.3 0.6 0.1 0.0 8.8 1.6 0.8 0.3 10.4 0.0 0.0 0.4 5.2 20.0 17.7 27.1 9.2 2.9 2.6 1.7 6.0 3.3 APOBEC1 "APOBEC-1, BEDP, CDAR1, HEPR" ENSG00000111701 "Apolipoprotein B mRNA editing enzyme catalytic subunit 1" P41238 12 7649400-7665908 "Enzymes, Predicted intracellular proteins" "mRNA processing" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 25 "intestine: 29.0" "Cell type enriched" "Detected in some" 5 "Proximal enterocytes: 153.8" "Group enriched" "Detected in some" 9 "colorectal cancer: 6.2;pancreatic cancer: 6.1;stomach cancer: 3.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 25 "CAPAN-2: 1.7;OE19: 4.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" "unprognostic (2.35e-1)" "unprognostic (3.80e-4)" "unprognostic (7.96e-3)" "unprognostic (1.79e-1)" "unprognostic (4.38e-1)" 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 29.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 26.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.3 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.3 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 10.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.2 28.2 0.0 0.0 0.0 153.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 4.9 0.0 ARL11 "ARLTS1, FLJ33930" ENSG00000152213 "ADP ribosylation factor like GTPase 11" Q969Q4 13 49628507-49633872 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 6.9" "Cell type enhanced" "Detected in many" "B-cells: 18.2;Hofbauer cells: 31.3;Kupffer cells: 34.8;Macrophages: 18.2;monocytes: 19.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "neutrophil: 38.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "Daudi: 7.9;HMC-1: 10.7;NB-4: 11.1;THP-1: 14.5;U-698: 6.6;U-937: 6.3" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA040855, HPA040887" Uncertain Approved "Intermediate filaments,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Intermediate filaments, Cytosol" "HPA040855: AB_10793864, HPA040887: AB_10796229" "unprognostic (1.19e-2)" "unprognostic (2.27e-1)" "unprognostic (2.07e-1)" "unprognostic (2.82e-1)" "unprognostic (7.86e-2)" "unprognostic (1.46e-1)" "unprognostic (1.12e-2)" "unprognostic (1.83e-1)" "unprognostic (3.60e-1)" "unprognostic (1.82e-1)" "unprognostic (2.72e-2)" "unprognostic (2.55e-1)" "unprognostic (2.27e-4)" "unprognostic (1.72e-2)" "unprognostic (5.60e-2)" "unprognostic (1.16e-1)" "unprognostic (3.14e-2)" 0.8 0.8 0.5 3.9 0.5 3.5 0.7 0.6 0.7 0.6 0.8 1.0 1.2 0.2 0.2 1.0 0.3 1.1 0.4 0.4 0.6 0.1 0.6 2.2 6.9 1.0 0.7 0.2 0.1 0.3 0.3 1.9 0.8 0.2 1.5 0.1 0.6 0.2 0.3 0.6 1.9 0.7 0.7 4.8 0.6 0.3 1.0 3.7 0.4 0.4 3.9 1.3 0.8 1.2 0.1 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.6 0.0 7.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 2.1 0.1 0.6 0.0 5.2 10.7 0.1 0.1 0.0 0.0 0.0 0.4 5.1 0.3 0.1 0.0 1.3 4.9 11.1 0.1 0.0 0.0 5.3 0.0 2.2 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.1 3.5 14.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 6.6 0.0 6.3 0.0 21.8 15.3 16.3 0.1 17.9 0.2 7.9 0.3 0.3 8.1 10.1 0.8 0.4 38.0 0.8 13.4 8.6 0.3 4.4 0.5 0.5 0.6 0.7 0.4 0.6 1.0 0.7 0.8 0.7 1.0 1.2 0.9 0.0 1.1 0.0 18.2 0.3 0.3 0.2 1.2 0.7 1.0 0.9 0.6 2.8 0.0 0.0 0.0 4.7 3.4 1.7 0.0 0.0 1.7 0.1 0.1 1.2 1.2 6.9 0.0 0.0 5.1 0.3 0.0 0.1 7.6 0.0 1.8 0.6 31.3 0.0 0.0 3.4 0.0 34.8 3.5 1.3 0.3 18.2 0.0 3.7 19.2 0.3 1.0 0.0 0.1 0.1 10.2 0.0 2.9 0.1 4.2 0.1 2.3 0.5 0.0 0.3 0.2 1.5 0.3 4.1 0.0 1.5 1.2 0.5 3.1 0.4 ARX "CT121, EIEE1, ISSX, MRX29, MRX32, MRX33, MRX36, MRX38, MRX43, MRX54, MRX76, MRX87, MRXS1, PRTS" ENSG00000004848 "Aristaless related homeobox" Q96QS3 X 25003694-25016420 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant, Epilepsy, Lissencephaly, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 17.4;ovary: 78.7;skeletal muscle: 26.7" "Group enriched" "Detected in some" 5 "Enteroendocrine cells: 83.7;Inhibitory neurons: 53.2;Leydig cells: 131.7;Peritubular cells: 70.0;Theca cells: 66.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 1.9;PC-3: 3.9;THP-1: 1.7;U-266/70: 8.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 52: Non-specific - Transcription" "unprognostic (8.28e-2)" "unprognostic (3.06e-2)" "unprognostic (1.98e-1)" "prognostic unfavorable (3.54e-7)" "unprognostic (9.85e-2)" "unprognostic (7.96e-3)" "unprognostic (1.18e-1)" "unprognostic (2.77e-3)" "unprognostic (1.60e-1)" "unprognostic (1.55e-3)" "unprognostic (1.32e-1)" "unprognostic (1.06e-6)" "unprognostic (6.01e-2)" "unprognostic (1.84e-1)" "unprognostic (1.15e-1)" "unprognostic (1.91e-1)" 0.0 0.1 7.6 0.0 10.1 0.0 0.3 0.0 17.4 0.0 0.0 0.9 3.5 0.0 0.1 0.1 1.1 0.0 0.0 10.1 6.0 0.1 0.0 0.4 0.0 0.0 0.0 78.7 1.4 1.8 0.3 0.0 0.1 0.7 0.9 0.0 0.2 0.0 26.7 0.0 0.7 0.0 0.0 0.2 5.5 7.2 0.4 0.0 0.2 1.9 0.4 0.0 0.2 8.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 1.9 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 3.9 0.4 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.7 0.0 0.0 0.1 0.0 0.0 8.3 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 10.1 0.0 17.4 10.1 6.0 0.0 0.0 0.1 0.0 0.4 8.0 0.0 0.0 0.0 14.0 0.3 0.0 2.5 0.5 0.0 0.0 0.3 0.0 0.5 0.0 2.2 0.0 0.0 0.2 0.1 1.9 0.0 0.0 1.2 0.0 0.0 0.1 83.7 0.0 0.2 0.0 2.4 4.7 4.6 0.0 0.0 0.4 0.0 0.0 0.1 0.0 53.2 3.6 4.1 0.0 0.0 3.6 131.7 0.2 0.0 3.7 0.0 0.0 0.0 3.5 0.6 0.3 0.8 70.0 0.9 1.3 0.1 0.1 11.3 0.0 0.0 1.5 0.3 0.5 0.3 0.0 0.0 0.1 0.3 66.8 1.9 1.6 ASAH2 ENSG00000188611 "N-acylsphingosine amidohydrolase 2" Q9NR71 10 50182778-50279720 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Lipid metabolism, Sphingolipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "intestine: 81.5" "Cell type enhanced" "Detected in some" "Late spermatids: 12.5;Muller glia cells: 9.0;Proximal enterocytes: 17.1;Sertoli cells: 6.6" "Low cancer specificity" "Detected in single" "Region enhanced" "Detected in many" "cerebellum: 8.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA061171 Supported Approved "Focal adhesion sites" "Intracellular and membrane" NA NA 2200000 "Cluster 32: T-cells - Unknown function" "Cluster 56: Intestine - Transmembrane transport" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 45: Enterocytes - Digestion" "Focal adhesion sites" "HPA061171: AB_2684442" "unprognostic (3.59e-2)" "unprognostic (3.63e-2)" "unprognostic (1.66e-1)" "unprognostic (3.84e-2)" "unprognostic (3.66e-1)" "unprognostic (4.48e-2)" "unprognostic (2.25e-2)" "unprognostic (1.08e-1)" "unprognostic (1.65e-2)" "unprognostic (4.33e-2)" "unprognostic (2.17e-1)" "unprognostic (1.14e-1)" "unprognostic (8.29e-2)" "unprognostic (1.86e-2)" "unprognostic (5.64e-2)" "unprognostic (3.22e-1)" "unprognostic (1.02e-3)" 0.4 0.8 0.0 0.2 1.1 0.0 0.5 8.1 0.4 0.7 0.1 0.8 81.5 0.8 0.5 0.7 0.8 0.3 0.8 0.1 0.4 0.5 2.9 0.6 0.3 3.2 2.9 0.8 1.4 0.6 0.6 0.6 2.2 0.4 0.4 7.3 0.6 0.2 0.8 0.7 64.6 1.2 1.5 0.2 5.0 0.8 0.6 0.5 0.7 0.4 0.1 0.5 0.4 0.6 1.2 0.9 1.0 1.4 1.8 0.7 1.3 1.2 0.9 2.5 2.2 0.7 3.0 0.0 1.4 1.9 2.0 1.1 1.4 0.4 3.0 1.6 2.5 0.9 2.2 1.9 1.1 0.3 0.1 0.2 1.7 4.3 4.8 0.3 0.5 0.0 1.7 0.8 1.7 1.1 1.0 0.0 3.2 0.0 2.7 0.0 4.2 1.1 1.3 0.2 1.8 4.8 1.7 1.2 2.1 2.4 1.0 0.7 1.4 1.2 2.8 3.2 4.0 1.2 0.1 0.0 3.5 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.0 0.3 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.2 0.1 0.0 0.0 1.1 8.1 0.4 0.1 0.4 3.2 2.9 2.2 1.5 0.6 0.6 0.1 0.0 0.0 0.7 0.0 0.4 0.3 0.4 0.0 2.8 0.4 0.3 3.8 0.0 0.9 0.0 2.1 0.4 1.4 0.5 0.0 0.9 4.8 0.1 0.2 0.5 0.0 3.2 1.1 1.6 0.3 0.6 0.0 0.2 0.0 0.2 0.4 2.1 0.2 1.7 1.5 1.8 0.0 0.0 0.0 12.5 1.2 0.0 0.0 0.0 0.0 9.0 1.0 0.0 0.2 1.6 0.1 1.5 0.0 0.3 17.1 1.0 0.7 2.1 6.6 0.6 0.9 1.9 0.9 0.0 0.1 0.3 0.5 0.2 1.2 0.2 ASF1B FLJ10604 ENSG00000105011 "Anti-silencing function 1B histone chaperone" Q9NVP2 19 14119512-14136613 "Predicted intracellular proteins" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Chaperone, Chromatin regulator, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 23.2;testis: 32.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 36.1;Early spermatids: 36.4;Erythroid cells: 43.6;Extravillous trophoblasts: 35.4;Spermatocytes: 73.2;Spermatogonia: 87.8" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 7 "neutrophil: 60.1" "Lineage enriched" "Detected in all" 7 "granulocytes: 60.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA054036, HPA069385" Enhanced Supported Nucleoplasm NA Yes "Cluster 9: Neutrophils - Innate immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA054036: AB_2682350, HPA069385: " "unprognostic (3.14e-1)" "prognostic favorable (4.45e-5)" "unprognostic (2.41e-3)" "unprognostic (2.40e-1)" "unprognostic (2.15e-1)" "unprognostic (2.27e-2)" "prognostic unfavorable (2.03e-4)" "unprognostic (2.87e-2)" "unprognostic (1.33e-3)" "unprognostic (1.52e-1)" "prognostic unfavorable (1.98e-4)" "unprognostic (8.48e-3)" "prognostic unfavorable (2.22e-16)" "prognostic favorable (2.49e-4)" "unprognostic (1.27e-1)" "unprognostic (3.92e-2)" "unprognostic (4.31e-2)" 0.9 1.4 0.2 5.6 0.3 11.7 1.3 0.3 0.2 2.2 0.1 7.4 5.3 1.0 0.1 10.3 0.7 0.7 0.7 0.1 0.2 1.0 1.3 2.1 12.5 0.3 0.2 0.7 0.7 0.3 0.7 3.6 0.3 0.8 7.7 0.0 1.9 0.3 0.5 3.2 6.0 2.0 0.2 6.7 3.2 32.0 0.3 23.2 0.6 0.4 14.7 1.8 3.2 0.3 64.6 25.3 37.7 28.9 3.8 3.6 16.2 33.1 28.3 63.8 79.5 26.5 31.6 59.1 30.0 17.5 26.5 38.0 41.8 24.1 49.7 54.0 26.9 55.5 48.7 18.6 0.2 39.0 35.1 0.7 1.7 35.8 12.4 7.2 25.1 44.1 50.2 83.8 31.8 75.7 80.8 34.3 17.3 69.1 56.7 77.0 56.0 51.6 20.1 28.3 46.0 16.5 39.8 29.2 17.4 10.3 22.1 41.5 10.6 36.0 21.6 91.0 56.6 43.2 46.5 80.3 28.0 71.9 36.1 0.7 6.2 1.5 1.7 8.0 0.9 1.1 1.5 2.0 1.2 0.9 0.9 1.7 60.1 1.7 8.5 0.5 5.1 3.2 0.2 0.3 0.3 0.2 0.1 0.2 0.3 0.2 0.3 0.2 0.3 0.3 1.0 0.0 0.6 0.3 5.6 2.5 2.4 4.5 1.2 0.1 4.8 8.5 1.2 1.5 1.1 0.0 0.0 36.1 3.8 11.7 0.0 1.0 36.4 2.1 1.3 2.1 1.2 43.6 0.5 1.2 35.4 4.1 23.4 2.3 4.5 9.2 0.4 0.3 21.5 0.0 0.4 9.9 8.2 5.6 5.6 29.1 0.0 5.0 1.8 1.0 2.1 0.3 4.1 0.0 0.5 1.1 2.2 0.7 20.1 1.0 2.4 0.3 0.2 0.9 0.0 1.1 3.3 73.2 87.8 8.3 1.1 10.4 5.3 3.0 20.9 2.4 ASPM "ASP, Calmbp1, FLJ10517, FLJ10549, MCPH5" ENSG00000066279 "Assembly factor for spindle microtubules" Q8IZT6 1 197084121-197146694 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Calmodulin-binding "Cancer-related genes, Disease variant, Mental retardation, Primary microcephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 10.1;lymphoid tissue: 17.0" "Cell type enhanced" "Detected in many" "Erythroid cells: 99.5;Granulosa cells: 121.1;Plasma cells: 44.8;Spermatocytes: 43.8;Spermatogonia: 44.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" CAB017816 Approved "Plasma membrane,Cytosol" NA Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Cytosol" "CAB017816: " "unprognostic (3.24e-1)" "unprognostic (1.56e-1)" "unprognostic (2.81e-2)" "prognostic unfavorable (1.97e-4)" "unprognostic (3.67e-1)" "unprognostic (3.47e-2)" "prognostic unfavorable (1.25e-4)" "prognostic unfavorable (2.41e-4)" "unprognostic (4.67e-3)" "unprognostic (9.29e-2)" "prognostic unfavorable (2.40e-4)" "unprognostic (1.03e-1)" "unprognostic (0.00e+0)" "unprognostic (7.31e-3)" "unprognostic (1.23e-1)" "unprognostic (4.94e-2)" "unprognostic (3.66e-2)" 0.2 0.1 0.0 3.0 0.0 10.1 0.4 0.0 0.1 0.2 0.0 1.6 2.1 0.3 0.0 1.5 0.0 0.3 0.1 0.0 0.0 0.0 0.6 0.3 5.3 0.0 0.0 0.1 0.0 0.0 0.0 1.5 0.0 0.1 1.9 0.0 0.2 0.0 0.0 2.7 1.9 0.7 0.0 0.9 1.1 3.2 0.1 17.0 0.1 0.0 5.1 0.6 0.4 0.2 44.6 22.9 39.1 23.2 1.9 5.5 14.7 35.1 23.2 32.6 25.6 16.7 31.1 45.4 12.5 27.5 13.8 40.2 33.6 12.1 39.1 41.8 25.4 33.1 56.1 12.8 0.4 51.9 20.5 0.6 1.0 26.1 15.2 7.3 31.5 32.9 41.8 50.7 29.0 16.0 40.6 10.3 17.8 24.8 6.4 30.2 55.5 31.7 7.4 11.4 20.4 29.5 50.6 20.6 9.5 20.8 26.9 12.7 28.9 20.9 20.0 34.9 61.2 13.9 21.6 26.8 14.9 11.0 42.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.6 0.0 1.1 1.3 5.8 6.1 1.5 4.0 2.2 0.1 2.4 2.4 1.1 0.0 1.3 1.8 0.0 20.0 7.8 7.7 0.0 0.3 3.9 2.9 6.2 4.3 0.0 99.5 2.0 0.0 14.8 9.8 13.3 8.1 1.3 121.1 6.4 2.2 11.6 0.0 4.8 6.8 4.1 6.4 2.4 4.5 0.6 6.4 0.0 0.0 0.9 0.7 4.1 0.0 1.0 0.5 0.2 1.5 44.8 2.0 0.4 0.4 0.8 0.3 0.0 0.6 7.0 43.8 44.7 27.1 3.4 3.7 9.1 5.7 16.9 2.1 ATP10B "ATPVB, FLJ21477, KIAA0715" ENSG00000118322 "ATPase phospholipid transporting 10B (putative)" O94823 5 160563120-160852214 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.1;gallbladder: 16.6;intestine: 45.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 136.4;Oligodendrocyte precursor cells: 293.0;Oligodendrocytes: 419.4;Undifferentiated cells: 90.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 19.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 10 "WM-115: 13.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA034574 Uncertain NA NA "Cluster 37: Intestine - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA034574: AB_10669992" "unprognostic (1.47e-1)" "unprognostic (1.03e-1)" "unprognostic (1.28e-2)" "unprognostic (4.47e-4)" "unprognostic (3.99e-2)" "unprognostic (6.10e-3)" "unprognostic (4.69e-2)" "unprognostic (4.86e-2)" "unprognostic (2.54e-1)" "unprognostic (1.20e-2)" "unprognostic (3.42e-2)" "unprognostic (5.12e-2)" "unprognostic (2.38e-3)" "unprognostic (5.13e-2)" "unprognostic (2.56e-1)" "unprognostic (3.38e-1)" "unprognostic (2.14e-1)" 0.1 0.0 4.1 5.0 9.0 0.0 0.4 8.8 6.4 1.0 0.1 44.5 24.7 0.0 12.3 6.2 0.4 16.6 0.0 4.3 5.0 0.1 0.0 0.0 0.0 10.6 7.8 0.0 2.9 0.0 0.0 0.0 9.9 0.0 45.7 0.0 1.8 0.7 0.0 7.1 21.0 1.5 5.8 0.0 4.8 0.3 8.0 5.0 0.0 0.0 2.9 1.5 2.5 17.1 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.5 0.1 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 13.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 9.0 8.8 6.4 4.3 5.0 10.6 7.8 9.9 5.8 8.0 17.1 0.1 0.0 0.0 42.7 0.6 0.4 0.1 12.9 0.0 0.0 0.1 0.0 1.2 21.5 15.1 1.8 0.0 0.0 0.0 136.4 0.0 23.6 0.2 0.2 0.0 0.3 13.2 0.0 4.0 20.3 0.1 0.0 10.7 0.3 0.0 0.0 0.0 0.3 0.1 0.0 3.9 55.4 4.1 0.0 1.2 0.6 0.0 0.1 1.8 1.9 1.6 0.0 0.0 293.0 419.4 16.4 64.7 0.0 0.4 0.1 24.1 0.0 16.0 0.0 0.0 0.0 0.6 0.0 0.1 2.9 0.9 0.5 0.3 0.0 90.7 6.5 ATP4A ATP6A ENSG00000105675 "ATPase H+/K+ transporting subunit alpha" P20648 19 35550031-35563658 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Potassium transport, Transport" Translocase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 83 "stomach 1: 841.9" "Group enriched" "Detected in some" 6 "Gastric mucus-secreting cells: 66.3;Late spermatids: 21.0" "Cancer enriched" "Detected in single" 21 "stomach cancer: 5.4" "Region enhanced" "Detected in single" "cerebellum: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA039154, HPA076684" Enhanced NA NA "Cluster 4: Stomach - Digestion" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA039154: AB_10672772, HPA076684: " "unprognostic (3.54e-2)" "unprognostic (6.98e-3)" "unprognostic (2.77e-2)" "unprognostic (1.43e-1)" "unprognostic (5.84e-3)" "unprognostic (4.96e-2)" "unprognostic (1.02e-1)" "unprognostic (1.50e-1)" "unprognostic (9.68e-2)" "unprognostic (1.47e-3)" "unprognostic (3.90e-3)" "unprognostic (3.92e-2)" "unprognostic (4.86e-2)" "unprognostic (1.23e-1)" "unprognostic (2.18e-1)" 1.1 2.5 0.0 0.0 0.0 0.0 0.0 1.0 0.3 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.2 0.2 0.0 0.0 0.0 10.1 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 841.9 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.0 1.2 0.4 0.0 0.0 66.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 21.0 0.6 1.2 0.0 0.0 0.6 0.1 0.0 0.0 0.1 1.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 2.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 ATP8A1 ATPIA ENSG00000124406 "ATPase phospholipid transporting 8A1" Q9Y2Q0 4 42408373-42657105 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 84.5" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 1218.1" "Cancer enhanced" "Detected in many" "thyroid cancer: 13.5" "Region enhanced" "Detected in all" "white matter: 84.5" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AN3-CA: 27.5;Daudi: 46.3;HEL: 16.4;REH: 16.1;SH-SY5Y: 14.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052935 Enhanced Supported Vesicles NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA052935: AB_2681992" "unprognostic (8.63e-2)" "unprognostic (3.43e-2)" "unprognostic (1.16e-2)" "unprognostic (7.61e-2)" "unprognostic (6.59e-2)" "unprognostic (6.82e-3)" "unprognostic (7.69e-2)" "unprognostic (2.02e-3)" "unprognostic (3.99e-1)" "unprognostic (2.99e-3)" "unprognostic (4.39e-2)" "unprognostic (9.71e-2)" "prognostic favorable (5.54e-10)" "unprognostic (2.43e-1)" "unprognostic (3.25e-1)" "unprognostic (8.21e-2)" "unprognostic (2.25e-1)" 2.8 8.9 5.8 9.5 26.7 23.4 3.7 3.6 18.3 2.1 0.0 12.8 4.2 2.4 12.2 2.2 2.4 2.5 8.4 14.5 11.7 3.8 1.7 11.8 15.0 9.5 4.4 16.2 7.0 36.0 2.2 2.4 9.5 8.3 11.7 19.4 4.4 5.3 10.0 1.7 8.9 2.8 18.1 9.0 12.5 2.1 9.5 9.9 39.7 15.6 11.8 2.5 1.5 84.5 0.0 0.1 0.4 27.5 0.1 0.1 0.1 0.1 0.0 0.0 0.0 3.0 0.4 46.3 12.6 0.2 0.0 2.4 6.5 0.1 0.0 7.4 4.5 16.4 1.6 0.7 0.1 4.0 0.3 0.4 0.0 0.0 0.0 0.6 0.2 10.3 0.0 5.1 0.0 2.0 6.0 1.4 2.0 1.9 0.6 16.1 0.0 5.3 9.5 0.6 4.9 14.8 0.3 9.4 0.0 1.1 3.1 0.0 0.4 0.0 2.0 0.5 0.0 1.7 0.0 9.4 0.7 5.6 0.2 0.0 0.6 0.6 3.7 0.2 1.9 1.5 1.1 4.1 0.6 2.5 1.7 4.4 0.5 2.2 2.5 2.4 1.0 0.6 5.8 26.7 3.6 18.3 14.5 11.7 9.5 4.4 9.5 18.1 9.5 84.5 26.1 28.9 80.1 136.1 23.3 1.5 1.8 0.6 2.2 19.7 4.0 1.5 14.4 0.0 5.3 5.5 81.3 0.0 52.9 48.4 3.9 0.2 4.6 1.3 1.3 13.6 84.6 13.9 295.9 2.5 0.1 4.8 19.9 4.2 8.2 26.5 16.8 1.1 1.6 62.2 255.9 28.6 0.0 8.8 4.6 2.9 3.4 8.9 3.6 31.9 5.1 2.2 33.0 144.8 1218.1 0.6 10.2 1.9 37.6 9.6 45.6 2.0 0.3 38.1 0.0 6.3 2.7 1.5 3.6 5.0 1.4 0.0 51.6 8.6 25.0 3.0 AURKB "Aik2, AIM-1, ARK2, AurB, IPL1, PPP1R48, STK12, STK5" ENSG00000178999 "Aurora kinase B" Q96GD4 17 8204733-8210600 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 44.1;lymphoid tissue: 60.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 40.5;Erythroid cells: 59.3;Extravillous trophoblasts: 89.1;Granulosa cells: 24.7;Hofbauer cells: 29.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "T-reg: 7.9" "Group enriched" "Detected in many" 6 "B-cells: 2.5;T-cells: 7.9" "Low cell line specificity" "Detected in many" "Group enriched" "Detected in some" 5 "basal ganglia: 1.3;white matter: 4.0" "Low region specificity" "Detected in all" "CAB005862, HPA037708" Enhanced Enhanced Nucleoplasm,Midbody Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Midbody "CAB005862: AB_449204, HPA037708: AB_2675623" "unprognostic (4.76e-2)" "unprognostic (3.61e-3)" "unprognostic (2.25e-1)" "unprognostic (3.14e-2)" "unprognostic (2.27e-1)" "unprognostic (6.05e-2)" "prognostic unfavorable (1.24e-4)" "unprognostic (1.99e-3)" "unprognostic (9.41e-3)" "unprognostic (3.47e-2)" "unprognostic (4.61e-3)" "unprognostic (1.01e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (7.77e-2)" "unprognostic (2.93e-1)" "unprognostic (6.76e-2)" "unprognostic (3.77e-1)" 1.1 1.2 0.1 14.2 0.2 44.1 1.7 0.2 0.2 3.0 0.1 11.1 12.1 1.6 0.4 18.6 0.6 1.5 0.7 0.1 0.2 0.9 2.0 2.5 36.7 0.1 0.3 0.5 0.6 0.3 0.2 8.2 0.3 0.8 11.0 0.0 2.7 0.3 5.5 9.3 11.6 3.2 0.0 12.0 4.6 1.2 0.4 60.1 0.6 0.0 36.6 3.5 5.9 0.2 196.5 130.9 191.1 93.0 4.2 6.5 73.4 91.7 49.5 186.2 170.6 171.5 57.4 193.3 46.2 37.0 77.0 139.8 140.1 62.6 153.7 84.9 231.3 115.7 78.3 146.1 0.7 62.2 109.2 3.5 2.9 109.4 67.7 18.5 86.5 123.6 73.3 73.4 82.9 92.9 225.1 87.4 119.6 63.9 57.6 149.8 176.1 80.5 41.2 38.2 41.2 59.1 81.7 36.5 61.2 56.5 63.5 41.4 33.9 74.3 75.6 67.6 243.3 53.2 37.7 147.9 35.7 92.9 153.4 0.0 0.4 0.6 0.5 0.3 0.1 1.1 1.3 2.1 0.5 2.5 0.1 0.7 0.9 0.3 0.2 0.2 7.9 0.9 0.1 0.2 0.2 0.2 0.1 0.2 0.1 0.3 0.3 0.0 0.4 0.2 0.3 0.0 0.5 0.0 7.6 4.5 1.8 6.1 0.6 0.0 1.8 2.2 1.4 0.0 2.6 0.0 0.0 40.5 1.8 13.2 0.0 0.4 0.1 0.5 1.6 3.1 0.0 59.3 0.0 0.0 89.1 5.7 6.1 2.1 4.5 24.7 6.1 0.7 29.4 0.0 0.0 10.8 0.0 5.7 7.3 0.2 0.6 5.1 1.8 0.0 0.9 0.0 3.1 0.0 0.1 0.3 2.8 0.0 15.4 1.2 1.5 0.1 0.2 0.0 0.0 0.1 4.8 1.6 7.2 11.8 2.4 9.0 4.3 1.0 22.0 2.8 AZGP1 "ZA2G, ZAG" ENSG00000160862 "Alpha-2-glycoprotein 1, zinc-binding" P25311 7 99966720-99976042 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 2809.6;salivary gland: 3847.3" "Cell type enhanced" "Detected in many" "Breast glandular cells: 1315.5;Breast myoepithelial cells: 704.8;Hepatocytes: 4270.8;Ionocytes: 901.3;Prostatic glandular cells: 1691.9;Urothelial cells: 674.2" "Group enriched" "Detected in many" 12 "breast cancer: 412.6;liver cancer: 273.6;prostate cancer: 469.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 56.6;OE19: 158.9;RPMI-8226: 130.4;T-47d: 41.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA012582, HPA012876, CAB016087, CAB032276" Enhanced Approved Nucleoplasm,Vesicles "Secreted to blood" NA NA 55200000000 74000000000 "Cluster 29: Non-specific - Vesicular transport" "Cluster 21: OE19 - Mitochondria" "Cluster 35: Glandular cells - Unknown function" Vesicles Nucleoplasm "CAB016087: AB_667849, CAB032276: AB_2062580, HPA012582: AB_1845226, HPA012876: " "unprognostic (8.14e-2)" "unprognostic (1.50e-1)" "unprognostic (3.41e-1)" "unprognostic (5.42e-3)" "unprognostic (4.98e-2)" "unprognostic (5.74e-3)" "prognostic favorable (2.90e-4)" "unprognostic (1.50e-1)" "unprognostic (1.85e-1)" "unprognostic (2.19e-1)" "unprognostic (2.35e-2)" "unprognostic (1.79e-1)" "prognostic favorable (1.53e-4)" "unprognostic (2.18e-1)" "unprognostic (2.08e-2)" "unprognostic (9.80e-2)" "unprognostic (3.51e-3)" 128.6 3.9 17.1 2.7 28.8 0.4 1061.4 23.1 18.8 3.4 16.0 6.7 30.9 1.5 2.5 22.0 3.0 38.7 114.7 14.9 22.2 326.8 2809.6 14.8 0.4 20.2 23.3 6.0 752.1 0.1 1.3 0.5 27.1 1051.4 4.2 3.6 3847.3 40.2 1.7 206.8 28.6 0.3 14.0 1.4 315.2 25.9 21.4 0.8 1.9 2.3 1.5 5.8 7.5 24.5 0.2 0.0 0.0 0.0 11.3 0.0 5.5 0.0 0.0 0.0 0.0 0.1 4.0 14.2 0.7 0.0 0.1 0.9 0.0 0.0 0.1 0.0 0.1 0.3 0.1 56.6 4.9 1.5 0.1 0.6 0.2 0.0 0.0 0.1 0.0 0.0 0.3 29.9 0.0 0.0 0.0 5.1 0.2 158.9 0.0 0.0 1.7 130.4 0.0 0.0 0.0 2.0 1.0 25.4 13.0 0.0 41.8 0.0 0.0 0.5 0.1 1.8 0.9 1.9 0.8 0.4 0.0 0.5 14.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.1 28.8 23.1 18.8 14.9 22.2 20.2 23.3 27.1 14.0 21.4 24.5 9.9 22.4 276.8 0.0 14.7 4.2 422.1 25.3 0.0 0.0 1315.5 704.8 115.9 451.8 63.0 5.5 2.1 0.0 10.4 5.5 46.9 11.7 1.9 1.4 1.2 14.2 12.4 85.5 0.1 254.2 0.0 7.7 94.8 5.5 3.8 1.2 65.3 4270.8 0.0 0.0 0.1 13.1 901.3 93.1 0.7 4.2 0.9 14.8 62.2 1.0 2.0 23.7 0.0 7.5 7.3 221.5 6.4 0.0 0.3 1691.9 15.3 596.1 6.3 0.3 0.0 0.0 11.9 7.4 0.4 9.9 9.7 0.0 12.3 0.1 12.6 674.2 B3GNT7 beta3GnT7 ENSG00000156966 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7" Q8NFL0 2 231395710-231401164 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 71.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 272.8;Intestinal goblet cells: 145.2;Paneth cells: 126.4;Undifferentiated cells: 354.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 32.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "CAPAN-2: 19.5;HEL: 15.6;THP-1: 14.0;WM-115: 23.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA013881, HPA035625, HPA035626" Enhanced Approved "Golgi apparatus,Mitotic spindle,Cytosol" "Intracellular and membrane" Yes NA 3600000 "Cluster 40: NK-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" "Mitotic spindle, Cytosol" "HPA013881: , HPA035625: AB_10601118, HPA035626: AB_2674707" "unprognostic (2.21e-1)" "unprognostic (1.15e-1)" "unprognostic (4.57e-3)" "unprognostic (1.46e-2)" "unprognostic (1.28e-2)" "unprognostic (2.69e-1)" "unprognostic (1.36e-1)" "unprognostic (2.31e-2)" "unprognostic (6.18e-2)" "unprognostic (5.82e-2)" "unprognostic (2.17e-2)" "unprognostic (7.77e-2)" "unprognostic (4.27e-3)" "unprognostic (6.96e-2)" "unprognostic (1.18e-1)" "prognostic favorable (6.00e-4)" "unprognostic (3.57e-1)" 3.1 12.9 5.9 2.8 5.1 14.2 3.8 4.0 5.8 2.5 4.6 56.2 25.2 1.9 6.8 2.9 4.6 14.0 4.7 5.6 6.5 2.2 1.2 15.3 1.6 6.0 7.0 16.7 25.4 14.3 8.8 5.4 5.3 3.2 71.2 2.1 7.5 4.4 0.4 5.0 28.4 2.3 4.3 5.1 35.6 1.3 7.3 2.4 8.4 0.3 1.5 3.7 0.6 5.4 0.7 2.8 0.3 0.6 0.1 0.2 1.0 0.2 1.1 0.1 0.1 1.4 19.5 2.2 5.8 0.3 0.2 5.1 0.2 0.0 0.1 0.3 0.5 15.6 0.5 0.9 0.1 0.1 0.8 0.1 1.4 0.2 0.3 1.1 0.2 0.4 0.5 0.4 0.1 0.9 0.2 0.7 6.3 7.7 3.3 0.3 0.1 0.4 0.6 1.7 0.5 0.8 0.3 1.7 0.7 6.9 0.6 14.0 0.2 0.4 0.4 0.2 0.2 2.3 0.9 0.7 0.3 0.2 23.7 0.7 0.1 0.7 2.9 0.5 0.5 9.9 0.1 0.4 6.5 7.0 0.1 0.7 0.2 32.1 0.6 3.1 0.2 1.0 5.9 5.1 4.0 5.8 5.6 6.5 6.0 7.0 5.3 4.3 7.3 5.4 0.9 41.7 30.2 0.3 8.7 2.3 1.7 8.7 0.0 0.4 5.2 2.5 1.1 95.8 29.7 1.8 2.1 0.6 61.7 272.8 0.0 16.1 0.4 13.3 2.2 4.7 103.0 0.4 0.5 84.3 64.9 2.3 51.5 18.5 9.5 17.3 3.3 0.2 11.2 0.0 0.4 145.2 18.3 10.1 38.6 1.2 1.5 9.7 3.6 0.0 2.9 0.5 10.3 55.3 0.2 69.8 126.4 8.2 5.5 11.6 93.2 0.4 82.2 1.8 0.0 0.5 2.3 0.9 1.4 0.0 2.7 2.1 10.0 0.4 354.6 16.2 BIRC5 "API4, EPR-1, survivin" ENSG00000089685 "Baculoviral IAP repeat containing 5" O15392 17 78214186-78225636 "Cancer-related genes, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Chromosome partition, Mitosis, Transcription, Transcription regulation" "Protease inhibitor, Repressor, Thiol protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 37.9;lymphoid tissue: 41.0;testis: 19.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 74.7;Early spermatids: 94.1;Erythroid cells: 166.7;Extravillous trophoblasts: 162.0;Spermatocytes: 191.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "T-reg: 14.1" "Lineage enriched" "Detected in many" 6 "T-cells: 14.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA002830, CAB004270" Enhanced Supported "Cytokinetic bridge" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Cytokinetic bridge" "CAB004270: AB_628302, HPA002830: AB_1857672" "unprognostic (8.04e-2)" "unprognostic (3.51e-2)" "unprognostic (4.48e-3)" "unprognostic (2.72e-3)" "unprognostic (3.37e-1)" "unprognostic (3.84e-2)" "prognostic unfavorable (5.28e-6)" "prognostic unfavorable (4.49e-4)" "unprognostic (3.56e-3)" "unprognostic (4.53e-3)" "unprognostic (2.87e-3)" "unprognostic (6.67e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.77e-2)" "unprognostic (4.70e-2)" "unprognostic (1.59e-1)" "unprognostic (1.16e-1)" 0.9 1.1 0.3 8.5 0.5 37.9 5.1 0.6 0.6 1.9 0.4 6.7 7.9 1.6 0.0 12.8 0.6 1.1 0.5 0.4 0.4 0.7 2.1 1.9 16.2 0.6 0.6 0.4 0.6 0.2 0.2 6.1 0.5 0.6 8.0 0.1 1.8 0.2 1.1 5.8 7.6 4.3 0.4 5.8 3.7 19.6 1.0 41.0 0.4 0.1 16.3 2.6 3.2 0.8 139.1 126.2 111.3 121.5 6.7 11.3 41.0 103.6 57.5 144.0 94.2 104.0 52.9 140.7 41.5 60.5 108.7 71.9 113.6 66.6 125.2 48.2 157.5 93.2 71.4 123.1 0.8 90.8 67.0 3.9 4.5 79.8 59.2 21.0 103.5 104.3 118.8 116.0 112.6 79.7 195.5 86.2 83.4 96.3 218.0 100.5 180.2 108.4 34.5 50.2 136.8 94.8 80.3 88.6 71.7 54.1 117.5 84.8 39.5 173.1 152.6 76.0 150.4 83.3 72.2 163.3 63.3 37.8 154.4 0.0 0.0 0.0 0.7 0.0 0.1 2.4 4.1 2.8 0.8 0.2 0.0 0.4 0.5 2.4 0.0 0.2 14.1 3.1 0.3 0.5 0.6 0.6 0.4 0.4 0.6 0.6 0.5 0.4 1.0 0.8 1.2 0.0 20.0 0.0 15.9 8.2 3.7 12.2 2.8 0.7 7.7 8.6 2.3 2.8 10.8 0.0 0.0 74.7 3.3 10.7 0.0 2.0 94.1 5.4 5.1 8.8 3.0 166.7 0.4 0.0 162.0 15.1 8.6 6.9 9.5 42.7 12.8 2.7 52.1 0.0 0.2 17.1 10.2 13.7 13.8 68.4 3.1 9.6 1.8 0.0 0.6 0.4 7.2 0.0 0.3 0.4 2.5 0.7 50.2 2.8 3.2 0.1 2.6 0.5 6.6 0.9 15.2 191.1 58.2 31.3 6.5 19.2 10.1 3.4 38.8 6.3 CACNA1A "APCA, CACNL1A4, Cav2.1, EA2, FHM, HPCA, MHP, MHP1, SCA6" ENSG00000141837 "Calcium voltage-gated channel subunit alpha1 A" O00555 19 13206442-13633025 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "brain: 99.3" "Group enriched" "Detected in many" 8 "Bipolar cells: 101.4;Enteroendocrine cells: 214.1;Excitatory neurons: 318.3;Horizontal cells: 249.0;Inhibitory neurons: 372.1;Oligodendrocyte precursor cells: 271.9" "Low cancer specificity" "Detected in some" "Group enriched" "Detected in all" 4 "cerebellum: 99.3;cerebral cortex: 30.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "SCLC-21H: 45.1;U-87 MG: 23.9" "Low region specificity" "Detected in all" "HPA064258, HPA068138, HPA071902" Enhanced Supported Uncertain "Endoplasmic reticulum" NA NA "Cluster 42: Non-specific - Transcription" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Endoplasmic reticulum" "HPA064258: AB_2685229, HPA068138: , HPA071902: " "unprognostic (1.09e-1)" "unprognostic (3.73e-3)" "unprognostic (2.27e-1)" "unprognostic (2.78e-4)" "unprognostic (4.00e-2)" "unprognostic (2.29e-3)" "unprognostic (5.47e-2)" "unprognostic (3.13e-1)" "unprognostic (2.86e-1)" "unprognostic (1.14e-2)" "prognostic favorable (4.32e-4)" "unprognostic (5.31e-3)" "unprognostic (5.03e-6)" "unprognostic (6.29e-2)" "unprognostic (1.59e-1)" "unprognostic (2.61e-2)" "unprognostic (6.25e-2)" 1.0 2.3 15.4 0.3 15.8 0.1 0.9 99.3 30.4 0.6 0.0 0.7 1.2 0.8 1.1 0.2 3.2 0.1 0.6 15.1 6.8 0.5 0.2 0.2 0.4 7.2 11.2 0.9 2.6 0.1 4.2 0.0 10.6 0.4 0.4 7.1 0.2 0.1 0.5 0.3 1.7 0.2 9.4 0.6 2.7 2.3 11.3 0.1 0.7 0.1 0.2 0.3 0.7 15.2 0.0 0.1 0.1 6.0 0.2 0.2 0.0 2.2 2.5 0.3 0.0 0.0 0.0 0.2 0.0 0.2 5.1 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 2.8 0.0 1.9 0.0 0.0 0.0 0.0 0.0 7.2 0.2 0.0 0.1 0.2 1.4 0.1 0.3 0.6 0.0 0.1 0.0 0.1 45.1 0.0 0.0 0.0 0.4 0.1 0.0 1.9 0.1 0.1 0.9 0.2 0.1 0.0 0.0 0.0 23.9 0.1 0.6 0.5 0.0 0.1 0.0 0.0 0.1 0.5 0.1 0.0 0.0 0.3 0.1 0.1 0.3 0.1 0.2 0.1 0.1 0.0 15.4 15.8 99.3 30.4 15.1 6.8 7.2 11.2 10.6 9.4 11.3 15.2 7.7 6.4 3.2 31.3 9.6 0.6 3.4 0.0 0.0 101.4 3.1 7.4 2.8 0.0 1.3 1.8 16.7 0.0 2.9 0.6 0.0 0.5 27.1 1.2 6.3 6.5 214.1 0.4 318.3 0.4 0.2 4.7 10.7 2.6 1.3 5.2 1.8 1.2 0.5 249.0 372.1 5.0 4.1 1.9 1.4 28.0 1.2 2.1 0.0 28.1 1.2 3.0 4.1 271.9 11.5 1.5 0.1 0.4 0.5 0.8 0.2 2.0 3.7 7.0 0.0 5.1 17.6 4.3 7.1 0.4 0.1 0.3 2.0 2.5 1.0 0.9 CALHM6 "C6orf187, dJ93H18.5, FAM26F, INAM, OTTHUMP00000017061, OTTHUMP00000017062, RP1-93H18.5" ENSG00000188820 "Calcium homeostasis modulator family member 6" Q5R3K3 6 116461370-116463771 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 136.6" "Cell type enriched" "Detected in some" 5 "Hofbauer cells: 138.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "intermediate monocyte: 724.6;non-classical monocyte: 861.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 28.0;Karpas-707: 45.1;RPMI-8226: 159.8;U-937: 59.7" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" "unprognostic (1.14e-2)" "unprognostic (2.31e-2)" "unprognostic (6.46e-3)" "unprognostic (7.15e-3)" "unprognostic (9.53e-3)" "unprognostic (4.10e-2)" "unprognostic (2.69e-1)" "unprognostic (1.68e-1)" "unprognostic (8.19e-2)" "unprognostic (1.24e-1)" "unprognostic (4.19e-1)" "unprognostic (1.20e-1)" "prognostic unfavorable (9.31e-10)" "unprognostic (1.69e-1)" "unprognostic (2.12e-2)" "unprognostic (3.85e-3)" "unprognostic (9.25e-3)" 7.4 7.3 4.9 60.2 5.2 41.4 10.0 4.5 6.6 4.3 5.0 10.4 12.2 2.4 3.6 4.1 4.1 7.2 4.3 4.7 5.2 4.1 24.7 10.8 73.0 8.1 4.7 4.5 1.8 1.7 4.8 12.5 5.3 5.4 7.0 1.1 5.7 3.0 1.6 1.9 20.9 11.8 5.6 136.6 7.9 8.2 5.3 14.0 2.4 2.6 23.1 11.4 3.0 5.4 6.4 0.0 0.6 0.4 0.5 2.0 11.7 0.2 1.3 2.0 1.3 0.0 1.0 0.2 3.5 1.5 0.0 0.0 0.3 0.2 4.2 0.7 0.4 28.0 0.0 0.0 2.8 0.1 0.1 2.2 0.0 0.2 0.2 0.5 0.7 0.0 0.0 45.1 5.5 0.0 2.7 4.8 3.6 0.0 0.0 2.4 0.0 159.8 2.2 0.3 2.7 0.1 14.9 0.1 11.7 1.6 0.2 7.3 0.1 0.0 0.2 0.1 0.9 11.4 0.2 0.0 0.3 59.7 3.9 22.0 205.7 50.1 16.6 724.6 16.6 231.8 23.0 15.5 193.8 308.9 28.9 15.2 115.8 27.4 861.9 86.5 2.7 175.6 4.9 5.2 4.5 6.6 4.7 5.2 8.1 4.7 5.3 5.6 5.3 5.4 0.6 0.0 1.7 0.0 9.7 0.0 0.0 0.0 0.0 0.0 0.8 3.2 0.0 0.0 0.0 0.0 0.0 1.7 2.7 0.0 0.0 0.6 0.0 0.2 0.3 0.8 0.0 0.0 0.0 10.0 9.0 0.7 0.0 0.1 0.0 1.4 0.0 0.0 138.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.8 0.0 0.0 10.3 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.7 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 2.2 1.2 1.8 0.0 0.0 CAPN5 "ADNIV, HTRA3, nCL-3, VRNI" ENSG00000149260 "Calpain 5" O15484 11 77066961-77126155 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 60.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 170.3;Gastric mucus-secreting cells: 80.0;Intestinal goblet cells: 89.8;Paneth cells: 72.6;Proximal enterocytes: 75.6;Undifferentiated cells: 69.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.3" "Lineage enriched" "Detected in single" 4 "T-cells: 1.3" "Cell line enhanced" "Detected in many" "OE19: 106.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033237, HPA072319" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Cytosol "CAB033237: AB_2069673, HPA072319: AB_2686512" "unprognostic (6.81e-3)" "unprognostic (1.31e-1)" "unprognostic (3.36e-2)" "prognostic unfavorable (2.16e-6)" "unprognostic (3.47e-3)" "unprognostic (1.34e-1)" "unprognostic (1.13e-1)" "unprognostic (5.30e-2)" "unprognostic (2.52e-1)" "unprognostic (2.21e-2)" "unprognostic (5.35e-3)" "unprognostic (4.64e-1)" "unprognostic (3.17e-3)" "unprognostic (8.58e-3)" "unprognostic (3.25e-1)" "unprognostic (2.31e-2)" "unprognostic (2.30e-3)" 6.7 12.2 8.5 10.9 7.9 2.7 4.9 6.4 8.6 13.5 3.5 60.5 60.7 10.0 5.7 31.6 10.8 36.3 7.2 8.5 8.7 15.1 52.1 4.8 1.9 11.7 8.2 13.2 5.6 1.0 5.1 2.8 12.5 16.0 49.9 3.8 7.7 8.9 1.6 3.1 52.4 11.3 9.9 3.5 47.9 21.5 7.9 2.8 4.7 1.7 2.7 15.4 10.5 8.1 0.8 12.5 8.6 7.8 32.0 30.4 0.7 11.8 22.9 13.4 10.0 6.9 3.6 0.4 7.7 24.5 14.4 0.5 3.8 1.0 6.4 0.5 0.8 2.1 0.5 0.9 7.9 0.2 0.4 16.1 1.4 22.6 5.2 18.8 14.4 5.1 0.2 0.0 26.9 19.9 1.8 0.3 6.6 106.6 9.3 2.0 27.0 0.4 4.6 16.4 0.5 13.5 1.0 2.7 5.9 5.7 1.7 0.1 23.9 25.4 12.3 34.8 1.3 0.8 1.7 0.1 13.1 0.3 5.7 0.0 0.2 0.0 1.3 0.3 0.1 0.0 0.1 0.5 0.2 0.0 0.6 0.8 0.0 0.0 0.0 0.1 0.0 0.7 8.5 7.9 6.4 8.6 8.5 8.7 11.7 8.2 12.5 9.9 7.9 8.1 1.6 0.0 0.5 4.2 1.0 1.7 0.3 2.2 0.0 3.1 0.5 1.8 1.7 24.3 10.3 23.9 0.0 0.1 3.4 170.3 1.9 10.3 1.1 1.9 5.9 2.4 22.3 5.7 4.6 32.7 0.4 7.6 80.0 3.5 0.0 10.2 2.9 40.4 0.9 1.7 6.7 89.8 10.2 1.6 1.8 1.3 12.5 1.2 7.2 1.0 0.3 5.8 5.2 11.6 0.7 22.4 72.6 4.5 0.9 2.0 75.6 9.9 11.1 2.1 0.0 8.3 4.1 0.5 2.3 2.5 0.9 0.0 1.5 5.3 69.2 2.4 CAPN8 nCL-2 ENSG00000203697 "Calpain 8" A6NHC0 1 223538007-223665723 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "stomach 1: 291.1" "Cell type enriched" "Detected in many" 6 "Gastric mucus-secreting cells: 910.8" "Cancer enhanced" "Detected in many" "pancreatic cancer: 28.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "OE19: 125.9;RT4: 76.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA073939 Approved "Nucleoplasm,Nuclear membrane,Vesicles" No NA "Cluster 4: Stomach - Digestion" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Nucleoplasm, Nuclear membrane, Vesicles" "HPA073939: AB_2686646" "unprognostic (4.87e-3)" "unprognostic (2.58e-1)" "unprognostic (1.89e-1)" "unprognostic (2.06e-2)" "unprognostic (1.32e-2)" "unprognostic (1.49e-1)" "unprognostic (7.97e-3)" "unprognostic (1.19e-1)" "unprognostic (1.26e-1)" "unprognostic (8.08e-2)" "unprognostic (2.72e-3)" "unprognostic (3.55e-1)" "unprognostic (4.12e-6)" "unprognostic (6.95e-2)" "unprognostic (5.59e-2)" "unprognostic (3.83e-2)" "unprognostic (5.44e-3)" 0.3 0.2 4.7 6.3 1.0 0.1 14.9 0.1 1.7 1.1 2.3 23.6 8.0 0.1 11.1 0.6 1.3 14.3 0.0 2.3 3.6 1.7 0.3 21.3 0.1 2.7 1.5 0.2 2.9 0.0 0.1 0.3 1.1 2.9 33.0 0.3 8.5 1.4 0.8 2.3 4.6 1.1 2.0 0.3 291.1 0.6 1.8 0.0 0.2 0.0 0.3 12.3 0.7 2.5 1.5 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.8 0.0 4.6 0.0 0.1 0.0 0.2 8.3 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.3 0.0 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 1.0 0.2 0.0 0.2 125.9 3.8 0.1 0.0 0.0 1.3 76.8 1.2 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 4.7 1.0 0.1 1.7 2.3 3.6 2.7 1.5 1.1 2.0 1.8 2.5 0.4 28.9 131.7 1.6 1.8 0.1 6.5 1.9 0.0 0.0 19.9 7.9 2.6 10.0 55.9 25.8 0.0 0.2 0.2 90.9 0.0 3.8 2.3 2.0 0.3 0.7 3.0 0.0 0.6 21.6 0.0 0.3 910.8 2.1 10.8 5.2 0.0 0.3 0.6 0.0 0.1 61.9 4.1 0.0 0.8 6.7 1.8 1.8 0.0 0.0 0.0 0.0 1.0 0.0 0.1 36.1 42.6 3.4 3.5 4.0 2.1 1.5 15.0 0.0 0.0 0.3 0.8 0.4 1.0 0.0 0.0 0.1 1.4 2.9 21.2 31.2 CBLIF "GIF, IF, IFMH, INF, TCN3" ENSG00000134812 "Cobalamin binding intrinsic factor" P27352 11 59829273-59845499 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted secreted proteins" "Cobalt transport, Ion transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1859 "stomach 1: 1575.7" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 11 "stomach cancer: 10.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA039908, HPA040774" Enhanced "Secreted to digestive system" NA NA "Cluster 4: Stomach - Digestion" "HPA039908: AB_10796335, HPA040774: AB_10795626" "unprognostic (2.78e-4)" "unprognostic (1.04e-1)" "unprognostic (2.45e-1)" "unprognostic (3.59e-1)" "unprognostic (1.66e-1)" 0.8 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.7 0.6 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.4 0.1 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1575.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CCNA2 "CCN1, CCNA" ENSG00000145386 "Cyclin A2" P20248 4 121816444-121823883 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Host-virus interaction, Mitosis" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 38.6;lymphoid tissue: 46.9;retina: 31.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 47.9;Erythroid cells: 102.1;Extravillous trophoblasts: 92.8;Plasma cells: 35.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 3.1" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basal ganglia: 3.4;white matter: 7.6" "CAB000114, HPA020626" Enhanced Enhanced Nucleoplasm,Cytosol Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cytosol" "CAB000114: AB_563675, HPA020626: AB_1847376" "unprognostic (4.02e-2)" "unprognostic (1.93e-1)" "unprognostic (7.66e-3)" "prognostic unfavorable (8.78e-4)" "unprognostic (1.25e-1)" "unprognostic (1.67e-2)" "prognostic unfavorable (9.17e-5)" "prognostic unfavorable (4.27e-4)" "unprognostic (3.92e-3)" "unprognostic (2.65e-2)" "prognostic unfavorable (4.43e-6)" "unprognostic (8.38e-3)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.65e-1)" "unprognostic (1.82e-1)" "unprognostic (6.07e-2)" "unprognostic (1.59e-1)" 1.5 1.2 2.5 11.4 2.5 38.6 2.5 3.5 4.7 4.3 2.5 9.8 10.1 2.5 0.6 8.4 2.2 1.8 1.3 2.3 2.4 1.5 1.6 1.8 25.0 2.8 2.7 3.8 0.8 0.6 2.7 10.5 2.6 1.9 11.5 31.7 1.8 0.8 0.7 6.7 9.9 4.0 2.6 4.6 4.4 6.2 2.6 46.9 1.2 0.5 24.4 2.9 3.9 3.5 177.1 45.3 120.5 51.8 6.4 16.3 98.8 119.7 52.8 156.7 115.6 99.4 106.5 161.2 31.7 63.8 55.0 58.0 154.2 71.1 128.0 77.8 70.8 129.7 56.0 96.9 1.5 197.0 88.0 4.2 5.3 65.1 38.7 24.7 95.4 84.3 187.9 156.9 126.1 63.8 251.8 113.1 95.5 109.9 49.8 114.1 233.5 78.2 44.8 34.6 51.0 53.8 63.1 76.0 32.4 89.8 63.7 81.9 56.5 72.7 109.3 77.4 115.9 98.0 112.3 181.9 41.5 197.6 82.4 0.0 0.1 0.3 0.1 0.0 0.0 0.1 0.9 0.6 0.4 0.0 0.0 0.2 0.1 0.8 0.1 0.0 3.1 0.9 2.5 2.5 3.5 4.7 2.3 2.4 2.8 2.7 2.6 2.6 2.6 3.5 0.8 0.0 1.1 1.6 5.7 2.8 1.5 5.5 1.8 2.9 1.9 1.8 0.8 0.0 1.6 0.0 12.5 47.9 1.9 4.9 0.0 0.7 9.6 0.6 2.7 3.3 1.2 102.1 3.3 0.2 92.8 6.3 9.2 2.1 0.0 18.1 4.2 0.9 25.3 0.0 4.1 7.7 8.2 6.9 3.6 2.1 0.9 3.6 1.8 2.8 0.2 1.2 0.0 4.5 5.2 0.5 3.1 1.2 35.5 3.3 1.8 0.2 2.5 14.2 0.0 0.9 6.0 10.3 17.7 24.0 1.3 8.5 6.3 1.4 19.9 2.1 CCNF "FBX1, FBXO1" ENSG00000162063 "Cyclin F" P41002 16 2429394-2458854 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" Cyclin "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 15.1" "Cell type enhanced" "Detected in many" "Erythroid cells: 37.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA060596, HPA070495, HPA071600" Enhanced Supported Centrosome NA Yes "Cluster 40: NK-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Centrosome "HPA060596: AB_2684329, HPA070495: AB_2686273, HPA071600: AB_2686424" "unprognostic (3.87e-2)" "unprognostic (2.21e-2)" "unprognostic (1.57e-3)" "unprognostic (3.70e-3)" "unprognostic (1.24e-1)" "unprognostic (1.13e-1)" "prognostic unfavorable (7.46e-7)" "unprognostic (2.45e-2)" "unprognostic (1.75e-2)" "unprognostic (1.99e-1)" "unprognostic (1.01e-2)" "unprognostic (1.58e-2)" "unprognostic (0.00e+0)" "unprognostic (1.22e-2)" "unprognostic (1.10e-2)" "unprognostic (4.25e-2)" "unprognostic (2.74e-1)" 1.4 1.0 2.5 3.8 2.1 7.3 1.9 2.9 2.7 1.3 0.0 2.0 2.8 0.8 2.0 4.0 0.8 0.8 0.6 2.4 2.0 0.6 0.7 1.0 7.4 1.5 2.0 1.0 0.8 0.5 0.8 2.5 1.3 1.6 2.0 0.8 2.1 1.1 1.3 4.8 2.1 1.1 0.8 2.2 1.6 2.7 2.6 15.1 0.7 1.3 9.6 1.7 1.5 1.7 21.0 32.4 31.3 28.9 2.2 2.9 23.8 24.1 12.2 34.2 26.1 64.6 25.6 42.3 8.0 14.1 10.2 33.1 52.2 19.6 16.4 30.9 23.4 46.1 35.3 20.4 2.3 30.4 30.7 2.0 2.5 24.1 11.7 4.4 25.5 36.5 52.0 28.5 17.6 45.6 46.1 25.0 31.2 22.6 13.2 76.2 35.1 39.5 9.5 9.3 29.8 17.0 36.0 32.8 6.4 15.6 34.3 16.6 18.1 19.1 46.7 13.5 27.1 16.4 20.9 74.5 5.6 31.8 26.9 0.0 0.3 0.0 0.7 0.1 0.4 0.6 0.4 0.9 0.1 0.4 0.3 0.4 0.0 1.3 0.3 0.5 0.5 0.6 2.5 2.1 2.9 2.7 2.4 2.0 1.5 2.0 1.3 0.8 2.6 1.7 0.9 0.0 3.9 3.3 2.7 2.8 2.7 1.4 6.2 5.3 2.4 2.0 1.9 0.0 1.6 1.8 12.5 7.0 3.7 2.4 0.0 1.2 0.9 1.0 2.7 2.2 1.2 37.5 5.7 0.6 12.2 2.2 5.6 1.0 1.3 8.9 2.5 0.9 6.1 8.4 5.6 2.6 4.1 2.4 1.6 0.0 1.8 1.5 5.4 0.0 0.8 0.9 2.1 1.0 1.0 1.1 0.3 2.6 7.2 1.9 0.9 0.2 0.3 1.6 0.0 0.8 2.7 3.9 5.7 3.5 1.1 1.9 3.4 1.7 4.7 1.6 CD163 "M130, MM130, SCARI1" ENSG00000177575 "CD163 molecule" Q86VB7 12 7470811-7503893 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Acute phase, Inflammatory response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 240.5" "Cell type enriched" "Detected in many" 4 "Kupffer cells: 1756.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 11 "classical monocyte: 76.1;myeloid DC: 65.2" "Group enriched" "Detected in many" 40 "dendritic cells: 65.2;monocytes: 76.1" "Cell line enhanced" "Detected in some" "GAMG: 1.8;HSkMC: 1.7" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "CAB002432, HPA046404, HPA051974" Enhanced Supported "Plasma membrane" "Secreted to blood" NA NA 903000000 1600000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "CAB002432: AB_563510, HPA046404: AB_2679655, HPA051974: AB_2681678" "unprognostic (1.13e-1)" "unprognostic (2.13e-1)" "unprognostic (5.02e-3)" "unprognostic (2.72e-1)" "unprognostic (6.17e-3)" "unprognostic (2.09e-1)" "unprognostic (1.02e-1)" "unprognostic (1.21e-1)" "unprognostic (2.78e-1)" "prognostic unfavorable (7.27e-4)" "unprognostic (1.04e-1)" "unprognostic (6.50e-2)" "unprognostic (1.84e-2)" "unprognostic (8.77e-2)" "unprognostic (4.95e-2)" "unprognostic (1.61e-1)" "unprognostic (1.20e-2)" 171.8 85.6 6.1 152.5 7.0 17.6 50.8 5.2 18.4 25.6 21.5 48.7 12.4 27.3 3.6 16.4 68.1 43.5 52.7 4.9 7.9 27.3 89.7 131.7 54.4 15.8 10.9 23.1 21.4 8.8 11.4 109.4 18.0 15.5 21.6 4.3 25.9 7.2 11.4 15.3 52.9 130.4 7.2 240.5 35.6 9.7 55.9 18.7 17.2 17.6 7.2 68.5 16.3 10.3 0.0 0.0 0.0 0.0 0.6 0.3 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 1.7 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.3 76.1 0.5 0.1 6.4 0.0 0.0 0.0 0.1 65.2 0.0 0.0 0.0 1.7 0.0 0.0 1.0 0.1 20.1 6.1 7.0 5.2 18.4 4.9 7.9 15.8 10.9 18.0 7.2 55.9 10.3 2.7 3.2 8.3 0.0 3.8 1.5 0.2 0.0 0.0 0.1 0.1 0.3 4.6 7.2 5.0 0.0 2.1 1.5 0.5 0.0 0.0 0.0 4.3 0.0 0.1 13.9 0.0 3.6 0.4 0.0 1.9 3.0 0.5 0.0 5.1 0.1 17.9 13.9 269.9 0.0 0.5 0.0 0.0 1756.1 30.9 6.4 5.0 387.9 0.0 2.8 41.1 0.9 1.0 0.0 0.0 0.0 0.0 1.2 1.0 0.1 0.0 0.2 1.6 0.2 118.3 1.7 4.0 3.9 2.6 0.5 1.0 3.0 1.3 0.0 0.0 0.1 CD53 "MOX44, TSPAN25" ENSG00000143119 "CD53 molecule" P19397 1 110871188-110899922 "CD markers, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 448.3" "Cell type enhanced" "Detected in many" "B-cells: 310.0;dendritic cells: 375.0;Hofbauer cells: 365.7;Kupffer cells: 324.3;Macrophages: 294.8;NK-cells: 383.1;T-cells: 297.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 473.5;HDLM-2: 214.8;HMC-1: 298.4;Karpas-707: 188.1;U-266/70: 251.2;U-698: 149.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047216 Enhanced NA NA "Cluster 38: Basophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 4: Macrophages - Innate immune response" "HPA047216: AB_2679986" "unprognostic (2.93e-2)" "unprognostic (1.25e-2)" "unprognostic (7.45e-3)" "unprognostic (1.02e-3)" "unprognostic (8.88e-2)" "unprognostic (3.78e-2)" "unprognostic (2.96e-1)" "unprognostic (6.07e-2)" "unprognostic (2.83e-2)" "unprognostic (2.03e-1)" "unprognostic (5.09e-2)" "unprognostic (1.62e-1)" "prognostic unfavorable (2.60e-4)" "unprognostic (9.58e-2)" "unprognostic (4.95e-2)" "unprognostic (1.33e-1)" "unprognostic (7.72e-2)" 63.4 30.8 10.1 284.4 11.1 126.6 27.0 12.6 16.3 20.8 12.3 41.5 37.9 17.3 10.5 20.0 22.8 58.5 12.2 9.7 13.4 15.1 46.8 114.9 397.9 18.9 16.0 9.2 11.9 6.6 6.2 58.5 18.9 12.8 54.8 2.0 19.3 12.8 4.5 6.7 103.4 55.8 18.3 269.4 44.3 5.7 17.5 144.9 11.3 10.6 448.3 85.1 9.0 31.9 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 473.5 0.2 0.0 0.2 0.5 0.0 0.0 0.0 214.8 0.0 26.4 0.1 0.0 0.0 60.4 298.4 0.0 0.0 0.0 0.0 0.0 0.0 139.2 11.2 188.1 0.0 0.0 103.1 71.1 0.4 0.0 0.0 98.0 0.7 104.2 0.0 0.0 0.0 0.1 0.0 0.2 0.2 1.5 0.0 88.4 17.2 0.2 0.4 0.1 0.5 251.2 123.2 149.2 1.5 68.7 3.4 1483.0 779.5 479.0 732.4 808.6 658.1 794.0 527.8 649.2 631.9 745.1 377.9 552.5 1144.2 526.6 882.9 517.5 740.3 1621.0 10.1 11.1 12.6 16.3 9.7 13.4 18.9 16.0 18.9 18.3 17.5 31.9 4.2 16.0 24.4 0.7 310.0 7.0 0.6 0.0 0.6 0.0 2.3 5.1 1.0 5.7 8.6 1.8 0.0 2.1 375.0 0.2 0.0 0.5 0.4 0.4 0.5 13.0 0.0 42.9 5.8 0.2 5.4 6.7 7.1 0.6 162.2 0.0 16.4 6.7 365.7 0.0 1.4 0.3 0.0 324.3 161.5 1.9 2.1 294.8 39.2 69.3 156.3 0.1 383.1 1.0 0.6 0.3 0.1 0.4 134.0 0.3 0.0 1.6 4.4 0.6 6.6 1.9 1.8 0.1 0.6 1.1 5.5 4.1 297.0 0.0 0.2 0.3 CD86 "B7-2, B7.2, CD28LG2" ENSG00000114013 "CD86 molecule" P42081 3 122055362-122121139 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity" "Host cell receptor for virus entry, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 34.5" "Cell type enhanced" "Detected in many" "Hofbauer cells: 121.3;Kupffer cells: 107.8;Langerhans cells: 148.3;Macrophages: 151.8;Microglial cells: 78.7;monocytes: 489.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "classical monocyte: 79.9;intermediate monocyte: 79.0;memory B-cell: 41.0;myeloid DC: 78.8;naive B-cell: 28.5;non-classical monocyte: 85.2" "Group enriched" "Detected in many" 18 "B-cells: 41.0;dendritic cells: 78.8;monocytes: 85.2" "Cell line enriched" "Detected in some" 7 "HDLM-2: 296.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004319, HPA026802" Approved Supported "Plasma membrane,Centriolar satellite" NA NA 160000 "Cluster 7: Monocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "Plasma membrane" "Centriolar satellite" "CAB004319: AB_627200, HPA026802: " "unprognostic (1.81e-1)" "unprognostic (3.78e-3)" "unprognostic (3.04e-2)" "unprognostic (3.52e-2)" "unprognostic (1.36e-1)" "unprognostic (2.79e-1)" "unprognostic (1.15e-1)" "unprognostic (8.56e-2)" "unprognostic (7.72e-3)" "unprognostic (1.21e-1)" "unprognostic (1.28e-1)" "unprognostic (1.98e-1)" "prognostic unfavorable (9.83e-5)" "unprognostic (9.72e-2)" "unprognostic (1.70e-2)" "unprognostic (9.78e-2)" "unprognostic (8.67e-2)" 7.8 5.3 3.5 34.5 3.4 10.3 4.4 4.0 3.6 3.5 4.8 6.3 3.7 2.4 1.0 4.0 2.1 14.3 2.7 3.2 6.1 1.9 11.2 18.6 28.8 7.2 5.5 2.1 2.6 2.9 1.1 15.0 7.0 2.4 7.7 0.9 2.3 2.5 0.8 2.0 6.8 7.4 5.3 23.4 5.2 3.1 5.0 10.6 1.3 0.8 22.0 14.9 1.0 10.2 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 40.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 296.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 2.5 0.2 0.0 0.0 0.2 0.0 32.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.4 0.4 0.0 0.1 0.0 0.1 15.1 0.6 35.1 0.0 0.9 0.0 0.1 79.9 0.8 0.0 79.0 0.0 41.0 0.2 0.3 78.8 28.5 0.2 0.1 0.9 3.7 85.2 8.3 1.6 33.4 3.5 3.4 4.0 3.6 3.2 6.1 7.2 5.5 7.0 5.3 5.0 10.2 0.9 0.0 7.7 0.3 36.5 3.6 0.1 1.3 0.0 0.0 0.4 1.3 0.3 1.5 3.2 1.8 0.0 1.8 3.3 0.0 0.0 0.2 3.7 0.1 0.0 2.6 0.0 1.3 0.2 3.5 0.8 0.8 0.5 0.0 2.5 0.1 1.8 0.8 121.3 0.0 0.3 0.0 0.0 107.8 148.3 2.7 0.0 151.8 7.2 78.7 489.4 0.0 0.0 0.5 0.1 0.3 0.0 0.0 20.6 0.3 0.0 0.1 0.1 0.4 0.0 0.3 0.7 0.2 0.3 0.2 4.0 1.9 2.1 0.1 0.0 0.3 CDC20 "CDC20A, p55CDC" ENSG00000117399 "Cell division cycle 20" Q12834 1 43358981-43363203 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Differentiation, Mitosis, Neurogenesis, Ubl conjugation pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 53.9;lymphoid tissue: 52.6;testis: 49.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 65.0;Early spermatids: 135.0;Erythroid cells: 96.0;Extravillous trophoblasts: 146.2;Spermatocytes: 126.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 7 "memory B-cell: 4.2;memory CD4 T-cell: 3.2;memory CD8 T-cell: 3.5;NK-cell: 9.5;T-reg: 11.6" "Group enriched" "Detected in many" 9 "B-cells: 4.2;NK-cells: 9.5;T-cells: 11.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "CAB004525, HPA045842, HPA055288" Enhanced Enhanced Nucleoplasm,Cytosol Yes Yes "Cluster 15: NK-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cytosol" "CAB004525: AB_628089, HPA045842: AB_2679470, HPA055288: AB_2682773" "unprognostic (1.66e-2)" "unprognostic (1.09e-1)" "unprognostic (1.73e-2)" "unprognostic (2.14e-3)" "unprognostic (1.58e-1)" "unprognostic (1.09e-1)" "prognostic unfavorable (4.00e-8)" "unprognostic (9.06e-3)" "unprognostic (1.17e-2)" "unprognostic (1.23e-2)" "prognostic unfavorable (1.32e-4)" "unprognostic (8.55e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.84e-2)" "unprognostic (2.28e-1)" "unprognostic (2.01e-1)" "unprognostic (1.29e-2)" 1.6 1.5 0.6 16.2 1.1 53.9 5.2 0.8 1.3 3.5 0.4 14.8 13.7 2.3 2.5 27.2 1.7 1.2 0.9 0.7 1.1 2.3 1.7 2.5 32.6 1.3 1.1 0.7 0.6 0.2 0.3 9.7 1.1 0.8 16.0 0.2 4.4 0.7 0.3 11.3 12.2 7.3 0.8 11.7 7.0 49.1 1.7 52.6 1.7 0.2 50.8 3.3 7.0 1.3 311.9 148.2 202.8 133.4 6.9 17.6 193.5 140.3 125.0 400.0 211.4 234.5 250.9 178.3 80.1 130.1 140.6 212.8 225.3 267.9 331.5 140.8 165.6 261.4 143.6 147.3 2.1 184.3 91.4 6.0 12.4 278.2 249.6 35.1 172.2 167.5 120.2 119.3 184.0 120.4 179.2 113.5 257.2 147.0 196.9 255.8 277.9 112.9 98.5 81.3 119.2 58.9 248.1 165.8 76.6 154.9 116.3 231.7 90.2 118.9 276.2 133.7 445.0 90.6 86.7 185.7 85.2 227.6 181.6 0.0 0.1 0.0 0.3 0.0 0.0 4.2 3.2 3.5 0.9 0.9 0.1 0.3 0.7 9.5 0.0 0.2 11.6 2.8 0.6 1.1 0.8 1.3 0.7 1.1 1.3 1.1 1.1 0.8 1.7 1.3 2.1 0.0 1.1 0.0 12.2 10.5 3.8 17.6 6.2 0.5 6.4 9.7 0.7 1.5 4.8 0.0 0.0 65.0 2.8 16.9 0.0 2.2 135.0 14.6 2.4 4.5 0.0 96.0 0.2 0.4 146.2 9.3 11.7 4.6 0.0 46.5 7.9 1.3 37.4 0.0 0.0 18.5 24.4 6.2 7.5 18.5 2.8 9.3 0.0 0.0 1.8 0.3 0.0 0.0 1.6 0.7 0.5 1.9 34.4 2.7 3.2 3.1 8.3 2.9 0.0 1.0 25.4 126.5 39.8 47.3 8.4 10.7 5.1 1.6 37.5 7.4 CDC25C "CDC25, PPP1R60" ENSG00000158402 "Cell division cycle 25C" P30307 5 138285269-138338355 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Host-virus interaction, Mitosis" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.8;lymphoid tissue: 8.9;testis: 18.1" "Cell type enhanced" "Detected in many" "Early spermatids: 41.4;Late spermatids: 42.1;Spermatocytes: 53.6;Spermatogonia: 13.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "CAB003800, HPA066991" Approved Enhanced "Nuclear speckles" No Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear speckles" "CAB003800: AB_562081, HPA066991: AB_2685760" "unprognostic (2.45e-3)" "unprognostic (5.89e-3)" "prognostic favorable (2.49e-4)" "unprognostic (9.72e-3)" "unprognostic (2.17e-1)" "unprognostic (1.53e-1)" "prognostic unfavorable (3.03e-6)" "prognostic unfavorable (4.38e-4)" "unprognostic (5.56e-2)" "unprognostic (2.08e-1)" "unprognostic (1.70e-3)" "unprognostic (1.00e-1)" "unprognostic (0.00e+0)" "unprognostic (5.04e-2)" "unprognostic (1.43e-1)" "unprognostic (2.59e-1)" "unprognostic (3.06e-1)" 0.2 0.2 0.2 2.1 0.2 5.8 0.7 0.3 0.3 0.3 0.2 3.4 3.0 0.4 0.2 1.4 0.2 0.2 0.1 0.2 0.2 0.1 0.5 0.3 3.2 0.2 0.3 0.0 0.4 0.1 0.1 1.2 0.2 0.2 4.1 0.1 0.3 0.1 0.0 1.4 3.0 0.8 0.1 0.9 1.1 18.1 0.2 8.9 0.1 0.0 4.6 0.5 0.5 0.2 27.9 11.0 38.4 28.9 0.9 3.6 9.9 16.4 17.5 36.2 50.3 27.3 52.8 13.3 13.8 10.1 40.5 14.9 31.7 25.9 34.9 11.1 21.5 9.6 15.0 21.2 0.3 6.3 10.0 0.8 0.9 22.0 18.0 3.8 24.6 28.9 14.8 24.2 22.9 15.5 19.3 16.7 9.7 22.3 12.2 11.9 34.2 15.0 6.4 8.4 19.2 11.9 36.8 11.0 16.9 32.6 18.7 13.9 7.2 19.9 16.8 13.9 26.5 15.0 13.4 13.0 8.3 14.3 15.6 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.6 0.1 0.2 0.2 0.3 0.3 0.2 0.2 0.2 0.3 0.2 0.1 0.2 0.2 0.1 0.0 0.0 1.3 0.9 0.6 0.3 1.1 1.8 0.0 0.9 0.8 0.3 0.0 0.2 0.0 0.0 5.0 0.5 1.8 0.0 0.1 41.4 0.4 0.9 0.6 0.0 9.5 1.3 0.0 6.9 1.1 3.6 1.2 0.0 5.5 1.4 0.4 2.7 0.0 1.0 3.9 2.0 0.6 0.5 42.1 1.8 1.2 0.0 1.0 0.6 0.0 0.0 1.0 0.3 0.0 1.4 0.4 4.5 0.3 0.9 0.1 0.1 0.0 0.0 0.2 0.9 53.6 13.0 4.3 0.4 1.4 0.6 0.2 4.9 0.6 CDK1 "CDC2, CDC28A" ENSG00000170312 "Cyclin dependent kinase 1" P06493 10 60778331-60794852 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Apoptosis, Biological rhythms, Cell cycle, Cell division, Host-virus interaction, Mitosis" "Host cell receptor for virus entry, Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 53.2;lymphoid tissue: 74.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 80.9;Erythroid cells: 209.6;Extravillous trophoblasts: 144.6;Spermatocytes: 110.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "NK-cell: 3.2;T-reg: 3.4" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003387, CAB003799, CAB079974" Enhanced Supported Nucleoplasm,Cytosol NA Yes 51000 "Cluster 15: NK-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cytosol" "CAB003799: AB_344898, CAB079974: , HPA003387: AB_1846356" "unprognostic (6.34e-2)" "prognostic favorable (8.81e-4)" "unprognostic (1.90e-1)" "unprognostic (6.82e-2)" "unprognostic (6.67e-2)" "unprognostic (3.83e-2)" "prognostic unfavorable (1.10e-6)" "prognostic unfavorable (7.88e-4)" "unprognostic (1.30e-2)" "unprognostic (1.30e-1)" "prognostic unfavorable (4.15e-6)" "unprognostic (1.80e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.27e-1)" "unprognostic (2.75e-1)" "unprognostic (2.13e-1)" "unprognostic (1.60e-1)" 3.8 1.8 0.9 17.0 1.0 53.2 7.4 0.9 1.5 5.2 0.9 17.6 16.3 7.1 12.2 17.5 3.7 4.3 1.4 0.9 1.0 3.1 3.2 4.7 40.6 1.2 1.2 2.3 0.8 2.5 4.1 19.4 1.1 1.7 20.8 1.3 3.2 5.2 1.4 13.2 14.5 8.0 0.9 9.0 10.1 25.1 1.4 74.0 3.6 2.2 47.5 7.1 6.9 1.0 249.9 93.5 241.1 96.0 15.4 23.6 99.0 183.8 132.7 218.8 209.0 218.9 213.7 226.2 69.6 50.6 79.6 149.9 166.2 106.8 225.8 162.3 121.1 119.4 84.4 128.1 2.8 184.5 117.6 4.7 10.4 142.1 137.0 49.6 133.3 146.2 185.1 270.3 246.9 66.3 234.0 131.1 106.6 149.3 193.1 199.7 224.5 111.3 84.3 81.4 112.7 98.7 123.5 184.9 96.3 130.0 199.9 111.5 55.4 92.8 197.9 99.1 255.8 104.9 180.8 205.6 79.9 203.5 117.6 0.0 0.0 0.0 0.3 0.1 0.2 0.5 0.7 1.3 0.3 0.4 0.2 0.7 0.0 3.2 0.1 0.9 3.4 0.9 0.9 1.0 0.9 1.5 0.9 1.0 1.2 1.2 1.1 0.9 1.4 1.0 7.7 0.0 3.2 0.3 7.1 39.8 5.4 29.9 2.8 1.1 5.3 6.1 0.8 0.0 10.2 18.4 0.0 80.9 3.6 8.9 3.9 0.8 18.7 10.8 6.2 10.5 3.0 209.6 0.4 0.0 144.6 13.3 13.3 9.4 0.0 51.5 7.5 1.3 57.2 0.0 0.2 14.6 30.5 20.5 18.1 10.4 2.1 16.5 1.8 1.9 1.0 1.0 3.1 0.0 0.1 0.4 0.7 0.7 32.1 4.3 2.2 3.0 17.6 0.7 0.0 0.5 24.6 110.0 39.6 33.8 18.6 22.0 10.3 2.1 26.6 10.4 CDKN3 "CDI1, KAP" ENSG00000100526 "Cyclin dependent kinase inhibitor 3" Q16667 14 54396849-54420218 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle" "Hydrolase, Protein phosphatase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 207.0" "Cell type enhanced" "Detected in many" "Early spermatids: 2630.9;Late spermatids: 659.4;Spermatocytes: 606.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 18.8" "Group enriched" "Detected in all" 6 "NK-cells: 6.4;T-cells: 18.8" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB005285, HPA039311, HPA058874" Enhanced Cytosol NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" Cytosol "CAB005285: AB_2078884, HPA039311: , HPA058874: AB_2683842" "unprognostic (3.46e-2)" "unprognostic (9.95e-2)" "unprognostic (5.79e-2)" "unprognostic (6.78e-3)" "unprognostic (2.73e-1)" "unprognostic (6.08e-2)" "unprognostic (1.51e-3)" "prognostic unfavorable (4.52e-4)" "unprognostic (2.50e-3)" "unprognostic (2.85e-3)" "prognostic unfavorable (7.46e-4)" "unprognostic (5.89e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.71e-1)" "unprognostic (7.30e-2)" "unprognostic (7.92e-2)" "unprognostic (4.31e-2)" 3.4 1.6 2.8 12.2 2.7 43.4 3.4 5.0 4.2 2.2 3.4 13.9 12.4 2.8 0.4 10.2 1.3 2.9 5.3 2.9 3.1 2.0 2.4 2.1 28.4 2.5 2.7 1.3 1.1 0.5 1.6 6.7 3.3 1.6 16.9 2.6 3.3 0.7 3.0 5.9 12.6 7.4 2.1 4.9 5.0 207.0 3.5 30.9 1.7 4.1 30.0 5.8 4.1 2.6 276.7 102.5 74.0 78.2 12.5 15.3 46.5 63.1 97.0 135.8 146.9 81.8 136.5 139.9 44.4 96.7 135.9 195.9 114.6 78.3 245.6 169.5 59.3 65.8 69.0 126.8 10.1 86.2 47.6 5.4 4.9 84.3 138.3 44.4 88.4 129.8 36.1 162.2 159.8 186.9 118.1 67.9 27.9 254.7 216.4 72.7 66.6 29.7 70.5 56.9 30.6 42.0 118.7 67.4 52.5 54.6 142.9 69.4 33.0 59.2 195.8 91.7 155.0 38.6 47.4 91.4 98.6 120.4 110.9 0.0 1.3 1.3 1.6 1.7 0.7 2.1 5.5 4.8 1.8 0.9 2.9 2.3 1.0 6.4 1.2 1.5 18.8 3.1 2.8 2.7 5.0 4.2 2.9 3.1 2.5 2.7 3.3 2.1 3.5 2.6 1.4 0.0 0.0 0.7 10.5 9.3 4.3 9.7 4.6 3.2 6.4 11.6 9.7 0.0 2.4 1.8 2.1 42.6 2.7 7.3 0.0 3.5 2630.9 2.7 3.5 6.8 7.8 125.5 2.5 2.4 35.0 10.2 9.2 3.5 7.0 31.3 6.1 3.1 37.7 5.0 3.9 17.9 4.1 9.8 8.8 659.4 21.5 8.9 1.8 1.0 2.9 1.7 0.0 0.0 0.2 1.9 7.2 10.5 41.0 4.0 3.4 2.8 0.2 2.9 0.0 3.0 20.5 606.9 39.8 22.5 6.5 4.1 8.3 3.9 31.2 5.3 CDT1 "DUP, RIS2" ENSG00000167513 "Chromatin licensing and DNA replication factor 1" Q9H211 16 88803789-88809258 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, DNA replication, Mitosis" "Disease variant, Dwarfism, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "bone marrow: 38.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 51.4;Erythroid cells: 71.3;Extravillous trophoblasts: 92.0;Spermatogonia: 37.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "NB-4: 149.4" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA017224 Approved Supported "Nucleoplasm,Nuclear bodies" NA Yes "Cluster 52: Eosinophils - Transcription" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nuclear bodies" "HPA017224: AB_1846468" "unprognostic (1.33e-1)" "unprognostic (2.04e-2)" "unprognostic (7.32e-2)" "unprognostic (2.67e-1)" "unprognostic (4.34e-1)" "unprognostic (1.98e-1)" "prognostic unfavorable (2.12e-6)" "unprognostic (3.44e-3)" "unprognostic (2.81e-2)" "unprognostic (4.59e-2)" "unprognostic (1.21e-1)" "unprognostic (9.34e-2)" "prognostic unfavorable (2.69e-6)" "unprognostic (7.72e-3)" "unprognostic (5.79e-2)" "unprognostic (2.80e-2)" "unprognostic (8.54e-2)" 0.7 0.8 0.8 3.8 1.2 38.5 0.7 2.5 1.3 1.7 0.0 3.3 4.1 0.5 0.2 6.7 0.5 0.2 0.5 0.8 2.3 0.7 1.0 1.3 4.8 2.2 1.1 0.4 0.6 1.3 2.1 2.8 1.9 0.7 1.6 0.4 1.1 0.2 0.1 3.6 3.9 0.6 0.7 3.1 2.4 3.5 1.1 8.7 0.6 0.0 3.3 0.5 2.3 1.0 33.6 34.5 16.5 25.3 0.7 3.4 64.2 24.1 6.6 19.4 12.0 79.3 33.8 51.4 24.2 5.5 12.7 46.0 21.6 17.7 6.2 18.2 92.1 51.8 28.8 59.9 0.3 28.8 21.5 1.8 1.4 19.8 4.4 1.6 5.9 60.9 80.8 18.4 7.6 90.6 109.3 149.4 41.8 12.2 31.6 120.3 22.9 42.4 4.3 23.8 36.6 26.2 44.4 13.1 16.9 7.4 39.0 55.9 5.9 24.6 42.6 37.2 35.4 61.4 55.7 73.6 19.3 71.9 31.6 0.2 0.1 0.9 0.3 0.0 0.0 0.1 0.1 0.2 0.3 0.2 0.1 0.1 0.7 0.4 0.1 0.1 0.7 0.2 0.8 1.2 2.5 1.3 0.8 2.3 2.2 1.1 1.9 0.7 1.1 1.0 0.4 0.0 1.1 0.7 4.9 11.2 4.3 1.4 7.4 0.7 5.4 7.5 2.2 1.5 1.7 1.8 0.0 51.4 2.2 12.7 1.9 1.1 0.4 1.4 1.4 2.2 2.4 71.3 0.2 0.0 92.0 5.2 9.2 2.2 0.0 29.0 0.4 1.0 19.5 0.0 0.8 16.1 4.1 5.6 5.5 1.2 0.3 2.8 1.8 0.0 1.9 1.5 4.1 0.0 0.6 0.6 2.3 0.4 23.1 2.2 2.0 1.6 2.1 1.9 0.0 2.1 3.4 6.6 37.1 10.8 7.1 24.8 5.4 5.7 30.1 4.4 CEACAM3 "CD66d, CGM1" ENSG00000170956 "CEA cell adhesion molecule 3" P40198 19 41796587-41811554 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "bone marrow: 44.3" "Cell type enriched" "Detected in some" 13 "Paneth cells: 56.4" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 6 "neutrophil: 289.3" "Lineage enriched" "Detected in many" 6 "granulocytes: 289.3" "Not detected" "Not detected" HPA011041 Approved NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA011041: AB_1078481" "unprognostic (1.60e-1)" "unprognostic (1.14e-1)" "unprognostic (2.23e-2)" "unprognostic (2.95e-2)" "unprognostic (2.19e-1)" "unprognostic (8.09e-3)" "unprognostic (1.44e-1)" "unprognostic (2.85e-1)" "unprognostic (1.49e-1)" "unprognostic (3.19e-2)" "unprognostic (1.62e-1)" "unprognostic (8.07e-2)" "unprognostic (1.32e-2)" "unprognostic (1.32e-1)" "unprognostic (4.68e-2)" "unprognostic (8.44e-2)" "unprognostic (2.83e-1)" 0.9 0.1 0.0 5.1 0.0 44.3 0.1 0.0 0.9 0.3 0.3 0.3 0.0 0.2 0.0 0.4 0.3 0.3 0.3 0.0 0.0 0.1 0.6 1.8 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.3 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.2 0.2 0.0 5.1 0.1 0.0 0.0 0.6 0.1 1.2 0.4 1.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 4.2 0.0 0.0 19.3 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 289.3 0.0 45.8 0.0 0.0 3.2 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 3.2 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 1.9 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.3 0.0 0.0 0.1 0.8 0.0 0.0 0.3 0.0 3.3 0.0 1.4 0.0 4.2 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.2 56.4 0.0 0.0 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.4 0.4 CELF3 "BRUNOL1, CAGH4, ERDA4, MGC57297, TNRC4" ENSG00000159409 "CUGBP Elav-like family member 3" Q5SZQ8 1 151700058-151716803 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Activator, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 70.7;pituitary gland: 109.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 101.4;Cone photoreceptor cells: 39.6;Enteroendocrine cells: 52.8;Excitatory neurons: 21.1;Horizontal cells: 20.2;Inhibitory neurons: 20.4" "Group enriched" "Detected in many" 5 "glioma: 4.4;pancreatic cancer: 4.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "SCLC-21H: 42.1;SH-SY5Y: 29.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006292 Uncertain Approved Nucleoplasm NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" Nucleoplasm "HPA006292: AB_10602250" "unprognostic (2.01e-1)" "unprognostic (1.79e-1)" "unprognostic (7.67e-2)" "unprognostic (1.96e-1)" "unprognostic (1.75e-1)" "unprognostic (6.64e-2)" "unprognostic (1.38e-1)" "unprognostic (3.02e-2)" "unprognostic (3.12e-1)" "unprognostic (3.48e-3)" "unprognostic (3.49e-3)" "unprognostic (6.90e-2)" "unprognostic (1.82e-8)" "unprognostic (8.50e-2)" "unprognostic (9.01e-2)" "unprognostic (2.41e-1)" "unprognostic (3.05e-2)" 0.1 11.2 41.9 0.2 41.1 0.3 0.0 22.1 70.7 0.0 0.0 2.1 3.0 0.0 0.0 0.0 0.8 0.0 0.1 48.5 37.5 0.1 0.0 0.1 0.0 8.6 16.4 0.0 6.1 0.0 109.0 0.1 10.9 0.1 0.7 23.6 0.0 0.0 0.0 0.1 2.1 0.2 5.2 0.0 4.9 3.1 28.5 0.0 0.1 0.0 0.0 0.1 0.2 20.5 0.0 0.0 2.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 42.1 29.2 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.9 41.1 22.1 70.7 48.5 37.5 8.6 16.4 10.9 5.2 28.5 20.5 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 101.4 0.0 0.0 0.9 0.0 0.0 0.0 39.6 0.1 0.0 0.3 0.0 0.0 13.1 0.3 0.0 0.0 52.8 0.0 21.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 20.2 20.4 1.5 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 2.2 0.0 6.0 0.7 0.1 0.1 0.0 0.0 0.1 0.0 0.8 0.0 5.5 0.0 0.0 0.1 2.1 0.4 0.0 0.0 0.1 0.0 0.0 0.1 0.1 CENPE "KIF10, PPP1R61" ENSG00000138778 "Centromere protein E" Q02224 4 103105349-103198445 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Developmental protein, Motor protein" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 10.0;lymphoid tissue: 9.2" "Cell type enhanced" "Detected in many" "Erythroid cells: 75.1;Extravillous trophoblasts: 28.4;Granulosa cells: 32.0;Spermatocytes: 75.3;Spermatogonia: 51.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "basophil: 2.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA011110, HPA042294" Enhanced Enhanced "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes Yes "Cluster 46: Basophils - DNA binding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Microtubules "Cytokinetic bridge, Mitotic spindle" "HPA011110: , HPA042294: AB_10797386" "unprognostic (1.62e-1)" "unprognostic (1.03e-1)" "unprognostic (5.64e-3)" "unprognostic (2.55e-2)" "unprognostic (1.65e-1)" "unprognostic (3.44e-2)" "unprognostic (2.40e-8)" "unprognostic (2.49e-3)" "unprognostic (1.59e-2)" "unprognostic (3.38e-1)" "unprognostic (4.88e-5)" "unprognostic (1.15e-2)" "unprognostic (0.00e+0)" "unprognostic (9.95e-3)" "unprognostic (2.49e-1)" "unprognostic (1.05e-1)" "unprognostic (2.37e-1)" 0.4 0.2 0.4 2.7 0.4 10.0 0.6 0.3 0.5 0.4 0.4 1.8 1.5 0.6 0.0 2.0 0.2 0.8 0.2 0.3 0.6 0.2 0.5 0.8 5.6 0.5 0.5 0.1 0.1 0.3 0.0 1.4 0.9 0.3 2.0 0.4 0.3 0.2 0.0 2.0 1.7 1.1 0.3 1.2 1.1 4.1 0.5 9.2 0.2 0.6 4.9 0.8 0.6 0.5 42.6 11.8 42.2 20.5 2.7 6.2 8.4 36.7 18.2 26.9 17.9 19.6 22.2 28.6 9.2 13.7 19.2 18.2 30.3 15.1 42.2 35.9 11.3 33.5 26.8 13.6 0.4 39.9 18.6 1.8 1.1 21.7 18.0 6.0 22.9 25.2 34.4 32.5 34.8 15.6 31.5 18.9 13.8 17.0 17.9 20.9 38.5 9.3 8.0 8.4 19.3 11.5 32.9 22.9 9.0 16.0 12.9 13.9 26.1 25.8 27.2 27.2 38.6 15.9 28.6 28.8 14.2 21.7 27.8 2.9 0.0 0.3 0.0 0.2 0.0 0.2 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.3 1.5 0.2 0.6 0.0 0.4 0.4 0.3 0.5 0.3 0.6 0.5 0.5 0.9 0.3 0.5 0.5 1.4 3.2 2.2 1.0 6.6 3.6 1.5 2.9 0.0 7.6 1.8 2.7 1.9 0.0 1.3 0.0 8.4 12.7 3.9 4.7 0.0 0.5 7.7 3.5 5.7 4.2 1.2 75.1 2.0 0.0 28.4 6.5 4.6 6.9 7.0 32.0 4.2 0.9 14.1 0.0 1.9 4.3 4.1 10.4 5.7 3.5 0.9 9.6 0.0 0.0 6.0 1.3 2.1 0.5 3.1 1.8 1.4 2.6 16.0 1.4 0.8 0.3 0.3 2.6 0.0 5.7 7.4 75.3 51.0 8.3 2.8 3.6 6.6 7.0 11.6 1.9 CENPM "C22orf18, CENP-M, MGC861, Pane1" ENSG00000100162 "Centromere protein M" Q9NSP4 22 41938737-41947152 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 29.0;lymphoid tissue: 25.1" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 116.7;Erythroid cells: 60.0;Plasma cells: 70.8;Respiratory ciliated cells: 102.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "T-reg: 50.8" "Group enriched" "Detected in many" 6 "B-cells: 38.6;T-cells: 50.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042404 Enhanced NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 12: Non-specific - Cell cycle regulation" "HPA042404: AB_2677981" "unprognostic (3.78e-2)" "prognostic favorable (3.40e-5)" "unprognostic (7.15e-3)" "unprognostic (2.65e-3)" "unprognostic (2.02e-1)" "unprognostic (1.16e-1)" "prognostic unfavorable (5.50e-5)" "unprognostic (1.46e-2)" "unprognostic (1.20e-1)" "unprognostic (2.74e-1)" "unprognostic (1.63e-2)" "unprognostic (1.34e-1)" "prognostic unfavorable (5.99e-7)" "unprognostic (9.54e-3)" "unprognostic (2.44e-1)" "unprognostic (8.73e-2)" "unprognostic (5.61e-2)" 1.3 1.5 0.6 9.9 0.6 29.0 1.9 1.8 1.1 2.3 0.3 9.9 8.4 1.7 0.1 9.9 10.8 2.0 0.7 0.5 0.7 2.3 1.6 3.8 25.1 0.8 0.8 0.7 0.7 0.3 0.5 3.2 0.8 1.4 5.3 0.1 3.6 0.3 0.9 8.0 8.3 1.8 0.5 10.6 6.1 12.8 1.0 22.6 0.8 0.4 16.3 2.0 4.0 0.5 79.1 79.0 43.5 28.8 3.3 3.3 18.4 37.8 19.4 65.2 66.2 92.3 41.0 101.5 27.8 20.2 42.2 29.5 32.9 38.8 16.2 29.4 137.4 47.8 82.3 64.9 3.2 91.4 51.9 2.7 2.9 42.1 19.3 6.9 24.8 91.5 36.7 95.0 38.8 121.9 91.9 94.8 23.6 47.5 58.1 86.8 43.4 105.6 26.9 46.5 49.3 9.4 58.5 34.5 20.6 7.2 32.8 58.4 12.5 62.8 93.4 42.0 64.1 50.5 38.0 95.2 21.9 75.9 70.0 1.8 0.3 0.0 6.2 0.2 8.8 27.9 18.6 8.4 0.7 38.6 3.5 4.6 1.1 7.4 0.2 0.4 50.8 7.9 0.6 0.6 1.8 1.1 0.5 0.7 0.8 0.8 0.8 0.5 1.0 0.5 0.4 0.0 3.4 0.3 50.7 2.0 4.8 17.8 1.8 1.9 10.9 10.3 0.6 0.0 7.9 0.0 0.0 39.7 5.4 25.3 17.6 2.1 4.5 116.7 4.2 2.6 7.7 60.0 0.5 0.7 38.9 6.4 10.7 18.0 2.5 15.8 3.6 1.3 43.4 3.3 0.8 34.5 28.5 2.9 3.5 6.7 1.2 5.4 7.2 1.0 1.8 0.1 2.1 1.0 0.2 1.5 8.4 0.4 70.8 2.8 4.0 0.3 102.6 0.6 0.0 0.2 7.0 36.4 29.8 13.3 1.0 8.8 18.5 2.9 36.6 9.0 CENPN "BM039, C16orf60, FLJ13607, FLJ22660" ENSG00000166451 "Centromere protein N" Q96H22 16 81006552-81033114 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 37.4" "Cell type enhanced" "Detected in many" "Erythroid cells: 64.2;Extravillous trophoblasts: 91.1;Spermatocytes: 52.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA052870 Supported Nucleoplasm NA NA "Cluster 24: B-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA052870: AB_2681978" "unprognostic (1.23e-2)" "unprognostic (2.40e-1)" "unprognostic (1.15e-1)" "unprognostic (1.76e-2)" "unprognostic (2.15e-1)" "unprognostic (1.76e-2)" "unprognostic (3.69e-3)" "prognostic unfavorable (6.49e-4)" "unprognostic (1.90e-1)" "unprognostic (2.36e-3)" "prognostic unfavorable (1.46e-5)" "unprognostic (3.02e-2)" "prognostic unfavorable (4.86e-4)" "unprognostic (2.34e-2)" "unprognostic (7.42e-2)" "unprognostic (1.41e-2)" "unprognostic (7.99e-2)" 5.1 5.0 3.2 7.9 4.0 37.4 3.6 3.1 4.9 2.8 2.1 8.0 7.8 2.3 3.1 7.5 1.6 3.1 5.7 3.3 3.1 5.4 9.0 3.3 11.0 3.8 4.0 1.5 5.2 8.6 1.6 8.9 3.4 18.7 7.6 1.4 2.5 2.7 4.5 3.8 6.4 6.4 2.7 4.3 5.2 11.2 3.9 18.1 2.8 2.6 12.0 6.0 2.8 5.8 86.2 81.0 64.9 58.4 16.9 15.1 82.6 97.5 59.3 137.0 59.6 150.8 64.6 48.1 52.4 48.9 62.7 69.9 53.1 61.5 172.9 29.3 47.9 43.0 63.3 100.9 9.6 64.6 80.4 14.0 6.6 123.3 40.8 18.0 62.6 59.1 83.6 65.9 66.9 160.1 78.0 79.6 69.7 37.2 45.4 90.9 64.5 51.3 22.5 58.6 43.2 38.9 140.3 31.8 40.1 38.9 76.2 34.0 38.5 97.7 101.1 66.8 96.8 46.4 112.1 186.8 45.8 43.7 85.8 0.9 1.4 2.4 2.1 2.8 2.0 1.6 2.7 1.5 6.6 5.9 1.3 1.5 1.7 3.6 3.1 2.2 7.9 2.0 3.2 4.0 3.1 4.9 3.3 3.1 3.8 4.0 3.4 2.7 3.9 5.8 2.8 0.0 4.8 1.0 10.2 24.0 15.7 9.6 14.8 1.0 6.0 7.0 4.8 5.7 5.8 3.7 0.0 47.1 10.0 7.4 0.0 5.7 41.8 4.5 3.8 5.8 1.2 64.2 1.9 6.5 91.1 9.7 11.7 6.4 6.3 13.2 6.8 6.3 27.2 0.0 1.1 12.8 12.2 9.7 20.2 40.9 2.8 10.4 7.2 1.0 4.4 0.8 0.0 0.5 6.1 5.1 4.0 3.4 34.7 13.6 5.1 8.8 1.8 0.4 0.0 7.1 10.0 52.3 39.1 32.7 16.3 27.2 10.9 6.3 22.0 16.6 CENPU "CENP-50, CENP-U, KLIP1, MLF1IP, PBIP1" ENSG00000151725 "Centromere protein U" Q71F23 4 184694085-184734130 "Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 62.6;testis: 29.5" "Cell type enhanced" "Detected in many" "Early spermatids: 489.7;Late spermatids: 900.3;Spermatocytes: 490.2;Spermatogonia: 215.1" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "basophil: 20.7;eosinophil: 14.2" "Lineage enriched" "Detected in many" 6 "granulocytes: 20.7" "Cell line enhanced" "Detected in many" "Karpas-707: 157.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA022048 Supported "Nucleoplasm,Centriolar satellite" NA Yes "Cluster 2: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 2: Karpas-707 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Centriolar satellite" "HPA022048: AB_1853985" "unprognostic (1.47e-1)" "unprognostic (9.88e-2)" "unprognostic (5.02e-2)" "unprognostic (2.37e-1)" "unprognostic (9.45e-2)" "unprognostic (4.97e-2)" "unprognostic (4.39e-3)" "prognostic unfavorable (7.51e-4)" "unprognostic (1.67e-3)" "unprognostic (3.34e-2)" "prognostic unfavorable (2.09e-4)" "unprognostic (7.27e-2)" "prognostic unfavorable (1.11e-9)" "unprognostic (2.19e-2)" "unprognostic (7.40e-3)" "unprognostic (4.46e-2)" "unprognostic (2.74e-1)" 1.5 1.1 0.1 5.4 0.3 62.6 5.7 0.6 0.3 2.4 0.1 7.8 5.1 1.5 0.7 10.5 0.9 1.1 1.5 0.2 0.2 0.7 3.7 1.7 16.2 0.2 0.2 0.6 1.0 1.4 0.2 4.8 0.6 1.3 8.0 1.5 2.7 0.4 0.9 15.3 5.4 2.7 0.2 2.3 3.7 29.5 0.4 12.8 1.3 0.1 13.6 2.1 3.9 0.5 57.8 17.1 67.9 35.8 4.3 6.4 37.6 40.8 19.4 32.2 21.2 24.8 32.1 45.9 3.8 18.7 20.2 23.0 52.4 33.2 30.6 23.4 23.0 50.4 17.5 12.6 0.7 71.1 29.3 2.7 2.1 33.3 8.4 9.4 32.1 53.9 44.1 157.3 51.1 38.2 111.4 53.0 33.8 12.7 21.5 74.5 24.3 15.6 17.1 26.7 52.0 49.0 31.4 39.4 23.9 25.0 44.1 50.2 20.9 23.8 31.3 23.5 39.7 26.5 29.5 37.6 37.2 55.4 94.5 20.7 0.7 14.2 0.5 2.0 0.4 0.9 0.7 0.8 0.4 0.9 0.6 0.8 0.1 3.5 2.8 1.9 2.5 0.6 0.1 0.3 0.6 0.3 0.2 0.2 0.2 0.2 0.6 0.2 0.4 0.5 1.4 9.6 3.2 0.3 6.5 13.9 6.0 11.5 3.4 0.9 11.5 7.9 2.3 4.3 8.7 1.8 0.0 31.5 5.4 8.9 3.9 4.8 489.7 9.5 4.0 3.8 0.0 115.7 0.4 2.5 48.4 7.3 9.2 6.6 8.9 27.1 1.1 0.9 21.6 0.0 0.4 10.0 10.2 5.1 7.3 900.3 9.0 15.3 0.0 1.0 5.3 0.2 4.1 0.5 1.9 3.0 1.0 6.8 28.3 2.6 0.9 0.7 5.6 1.4 19.7 2.0 7.2 490.2 215.1 29.1 21.5 7.5 6.3 4.4 18.1 11.6 CKMT2 SMTCK ENSG00000131730 "Creatine kinase, mitochondrial 2" P17540 5 81233320-81266398 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 49 "heart muscle: 1240.1;skeletal muscle: 1430.8;tongue: 2324.4" "Cell type enriched" "Detected in many" 20 "Cardiomyocytes: 814.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "NK-cell: 1.1" "Lineage enriched" "Detected in single" 7 "NK-cells: 1.1" "Cell line enhanced" "Detected in many" "BEWO: 3.5;T-47d: 6.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA051880 Enhanced NA NA 3000000 "Cluster 48: NK-cells - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 6: T47d - Mammary gland" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA051880: AB_2681650" "unprognostic (3.64e-3)" "unprognostic (1.15e-1)" "unprognostic (2.82e-3)" "unprognostic (1.88e-2)" "unprognostic (1.21e-2)" "unprognostic (2.41e-2)" "unprognostic (1.73e-2)" "unprognostic (3.57e-2)" "unprognostic (2.12e-1)" "unprognostic (1.03e-1)" "unprognostic (2.82e-1)" "unprognostic (1.84e-1)" "unprognostic (1.60e-2)" "unprognostic (5.34e-2)" "unprognostic (2.28e-1)" "unprognostic (1.76e-1)" "unprognostic (2.75e-3)" 18.2 33.6 12.3 0.8 15.0 0.1 4.6 17.3 12.3 8.1 24.4 3.2 1.1 6.4 11.4 20.2 6.9 8.1 1240.1 11.2 15.0 14.7 1.0 2.5 1.3 16.3 16.8 10.2 7.7 15.7 4.5 0.7 14.9 13.1 0.7 1.6 26.3 13.1 1430.8 4.7 2.8 8.8 12.0 1.8 17.9 3.6 16.1 0.8 4.9 2324.4 0.4 4.1 4.1 17.7 0.3 0.7 0.8 1.3 1.9 0.4 3.5 0.1 0.0 0.0 0.0 2.4 0.2 1.4 0.4 0.0 1.0 0.0 0.0 0.0 0.0 1.5 2.4 0.1 1.0 3.2 2.6 0.6 0.2 0.8 0.0 0.0 0.0 0.3 0.0 2.1 0.3 0.5 0.0 2.2 1.2 0.2 1.0 0.0 0.7 0.6 1.0 0.1 0.0 0.0 1.4 1.0 1.2 0.3 1.4 1.5 6.3 0.3 0.7 0.4 1.2 0.7 0.2 0.2 0.1 1.3 0.4 0.9 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.0 12.3 15.0 17.3 12.3 11.2 15.0 16.3 16.8 14.9 12.0 16.1 17.7 1.8 0.0 0.5 40.1 0.0 0.1 0.4 0.0 1.2 0.9 0.9 0.8 814.1 7.2 0.6 12.9 0.0 0.1 0.0 0.1 37.2 1.7 25.1 13.6 3.5 9.8 0.0 0.0 11.4 0.6 0.4 16.2 6.6 27.8 0.0 0.8 0.0 0.0 0.1 0.0 18.1 0.3 0.0 0.0 0.0 2.2 7.2 0.3 3.6 23.4 0.0 1.4 0.0 4.5 9.1 0.4 0.0 15.1 0.0 0.3 0.3 0.6 0.7 1.0 0.0 11.6 15.0 1.0 0.4 0.1 0.1 0.3 0.8 23.7 2.5 0.2 CKS2 ENSG00000123975 "CDC28 protein kinase regulatory subunit 2" P33552 9 89311195-89316703 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 177.3;testis: 186.3" "Cell type enhanced" "Detected in many" "Langerhans cells: 474.6;Spermatocytes: 692.7;Spermatogonia: 503.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 187.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003424, HPA030762" Approved Approved Nucleoplasm,Vesicles,Mitochondria,Cytosol NA Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" "Mitochondria, Cytosol" "Nucleoplasm, Vesicles" "HPA003424: AB_2666948, HPA030762: AB_10670044" "unprognostic (8.30e-2)" "unprognostic (3.00e-1)" "unprognostic (1.50e-2)" "unprognostic (2.80e-2)" "unprognostic (2.96e-1)" "unprognostic (1.35e-1)" "prognostic unfavorable (2.51e-6)" "unprognostic (3.57e-3)" "unprognostic (7.04e-2)" "unprognostic (1.34e-2)" "prognostic unfavorable (6.85e-4)" "unprognostic (1.24e-2)" "prognostic unfavorable (1.78e-5)" "unprognostic (2.13e-3)" "unprognostic (1.44e-1)" "unprognostic (2.84e-1)" "unprognostic (1.84e-1)" 13.6 82.9 9.6 38.5 10.0 177.3 20.1 11.9 26.9 10.1 11.8 44.1 43.3 13.0 8.8 53.2 12.1 18.7 10.3 12.7 10.3 35.6 31.2 24.0 102.8 10.5 10.1 9.4 4.2 19.8 4.8 44.3 11.0 15.0 41.0 27.9 10.8 17.8 9.4 19.9 33.1 17.6 10.6 32.6 20.4 186.3 10.8 121.1 12.8 4.8 84.7 26.5 19.9 11.3 685.9 570.1 342.6 230.6 98.7 89.1 249.5 396.1 211.4 428.1 340.0 236.1 328.6 504.9 228.4 149.1 761.4 466.5 415.5 305.1 488.2 398.1 335.5 257.5 378.9 637.5 42.4 531.7 281.2 33.0 69.2 307.2 269.1 162.9 403.2 409.1 313.2 430.6 556.0 509.1 420.7 928.3 501.6 795.5 521.5 358.4 376.4 303.7 342.8 153.5 288.4 171.7 328.7 314.9 324.5 318.4 379.7 304.2 231.4 184.1 350.3 449.6 588.2 345.9 759.2 415.3 271.3 303.1 268.5 40.8 19.5 44.1 22.6 26.5 25.3 61.3 30.4 21.9 22.5 44.7 16.3 21.8 14.5 40.9 14.8 187.9 62.7 23.6 9.6 10.0 11.9 26.9 12.7 10.3 10.5 10.1 11.0 10.6 10.8 11.3 138.6 38.5 103.9 0.3 175.7 280.2 92.1 126.1 259.0 4.1 107.2 169.0 61.3 5.7 49.9 14.7 0.0 231.1 201.1 79.4 23.5 20.1 37.3 149.7 66.4 66.1 122.3 266.9 1.2 11.2 379.4 63.1 74.9 250.2 145.0 144.7 29.3 25.0 184.6 0.0 1.9 164.9 111.9 40.5 474.6 77.0 25.7 164.3 140.5 1.9 31.0 26.1 28.8 1.0 1.1 31.1 67.1 16.6 89.3 72.1 37.6 209.7 32.8 7.3 46.0 75.2 206.5 692.7 503.6 197.5 299.1 199.5 156.0 70.3 162.7 102.1 CLCNKA hClC-Ka ENSG00000186510 "Chloride voltage-gated channel Ka" P51800 1 16018875-16034050 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Ion transport, Transport" "Chloride channel, Ion channel, Voltage-gated channel" "Bartter syndrome, Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "kidney: 344.0" "Cell type enriched" "Detected in some" 4 "Late spermatids: 271.5" "Group enriched" "Detected in some" 7 "renal cancer: 4.4;thyroid cancer: 1.6" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "U-266/70: 7.4" HPA057717 Approved NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 31: Spermatids - Spermatogenesis" "HPA057717: AB_2683509" "unprognostic (2.35e-2)" "unprognostic (1.24e-1)" "unprognostic (1.37e-2)" "unprognostic (4.02e-1)" "unprognostic (2.76e-3)" "unprognostic (8.20e-2)" "unprognostic (6.16e-2)" "unprognostic (1.18e-2)" "unprognostic (6.92e-3)" "unprognostic (3.49e-2)" "unprognostic (1.76e-2)" "unprognostic (1.41e-1)" "unprognostic (8.13e-3)" "unprognostic (1.36e-1)" "unprognostic (9.13e-2)" "unprognostic (4.37e-3)" "unprognostic (1.28e-1)" 0.7 2.9 0.4 0.0 0.4 0.0 0.9 2.2 0.4 0.6 4.9 0.4 0.0 0.6 0.5 0.0 0.5 0.1 0.6 0.7 0.4 344.0 0.2 0.3 0.0 0.4 0.5 0.9 3.5 48.9 18.2 0.0 0.7 0.8 0.0 2.3 6.9 0.2 0.5 0.7 0.1 0.2 0.3 0.1 3.9 4.5 0.4 0.0 21.6 0.3 0.0 0.2 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.2 1.6 0.0 0.0 0.0 0.0 0.0 1.7 0.1 0.2 0.1 0.3 0.0 0.0 0.0 0.0 0.0 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 2.2 0.4 0.7 0.4 0.4 0.5 0.7 0.3 0.4 0.4 0.0 3.2 0.5 0.3 0.0 0.1 0.1 0.0 0.0 3.9 0.4 0.1 3.8 0.0 0.7 25.8 0.0 0.4 0.0 0.1 25.4 0.3 40.2 0.1 0.0 0.1 1.2 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 4.5 0.0 0.0 0.1 13.5 0.2 0.1 67.1 0.0 0.0 271.5 0.3 0.0 1.8 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.3 0.0 0.7 0.0 0.0 0.1 1.9 1.2 0.0 0.0 0.7 0.1 0.0 0.3 0.2 CLEC11A "CLECSF3, LSLCL, P47, SCGF" ENSG00000105472 "C-type lectin domain containing 11A" Q9Y240 19 50723364-50725718 "Plasma proteins, Predicted secreted proteins" Osteogenesis "Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 132.6" "Cell type enhanced" "Detected in many" "Distal tubular cells: 119.3;Fibroblasts: 107.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 24.3" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 4 "HEL: 363.0;HMC-1: 637.3;NB-4: 901.1;THP-1: 694.7;U-937: 358.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA042690 Approved Approved Centrosome "Secreted in other tissues" NA NA 1300000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 24: NB-4 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" Centrosome "HPA042690: AB_10795511" "unprognostic (9.33e-2)" "unprognostic (6.66e-2)" "unprognostic (2.40e-2)" "prognostic favorable (6.91e-4)" "unprognostic (2.33e-1)" "unprognostic (8.22e-2)" "unprognostic (5.52e-2)" "unprognostic (1.29e-2)" "unprognostic (5.26e-2)" "unprognostic (4.99e-2)" "unprognostic (2.79e-2)" "unprognostic (8.30e-2)" "prognostic unfavorable (1.02e-5)" "unprognostic (6.09e-2)" "unprognostic (8.66e-3)" "unprognostic (4.00e-2)" "unprognostic (1.57e-2)" 17.5 17.5 5.0 7.0 5.6 132.6 14.1 7.9 9.1 44.4 2.9 12.0 4.8 31.9 1.6 8.4 37.5 6.2 16.3 4.4 7.2 21.1 12.1 15.0 2.7 10.2 7.9 31.5 7.5 2.4 22.3 5.5 8.1 22.5 1.9 0.7 6.9 4.8 4.4 16.8 9.7 8.1 7.2 14.0 8.0 9.1 6.2 2.6 12.8 1.0 0.8 19.2 28.2 6.0 2.6 3.5 0.0 2.9 33.7 45.3 79.2 139.3 37.9 15.6 15.7 0.1 0.0 0.4 1.7 70.2 0.8 1.6 0.4 0.2 10.7 0.6 22.9 363.0 0.1 0.0 21.3 0.2 637.3 33.7 0.2 1.9 2.3 0.1 17.9 16.1 4.1 2.2 29.0 2.6 3.1 901.1 1.6 0.3 4.6 30.7 0.2 0.2 0.8 0.4 0.0 3.8 4.2 0.0 58.1 0.0 0.9 694.7 100.3 1.1 41.6 0.7 0.7 2.1 2.2 0.5 47.3 358.7 44.2 1.4 24.3 0.4 0.9 11.5 0.1 0.6 0.3 0.2 17.7 0.4 2.0 4.5 1.6 5.7 5.6 4.8 0.2 8.2 5.0 5.6 7.9 9.1 4.4 7.2 10.2 7.9 8.1 7.2 6.2 6.0 12.4 3.2 5.4 10.4 3.9 32.0 32.2 2.9 27.3 20.5 30.8 31.9 3.4 8.6 4.0 29.5 10.4 8.6 5.0 1.7 119.3 11.0 6.5 17.0 70.7 16.9 26.5 36.4 9.0 3.1 72.4 107.2 4.1 14.1 5.7 18.9 51.4 6.3 49.4 21.9 8.3 4.5 10.2 21.5 73.3 19.9 70.8 29.6 78.2 9.4 11.2 70.4 14.4 8.0 12.9 3.1 1.7 67.4 0.9 21.4 0.5 13.7 5.0 20.7 65.7 20.2 59.2 17.2 21.7 26.3 45.9 18.3 5.8 56.7 3.5 17.8 CLIC6 "CLIC1L, CLIC5" ENSG00000159212 "Chloride intracellular channel 6" Q96NY7 21 34668994-34718227 "Predicted intracellular proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "choroid plexus: 235.9;stomach 1: 138.5" "Cell type enhanced" "Detected in many" "Cholangiocytes: 30.0;Club cells: 41.6;Gastric mucus-secreting cells: 26.5;Respiratory ciliated cells: 81.1;Skeletal myocytes: 24.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 2.6;NTERA-2: 3.6;T-47d: 7.3;THP-1: 3.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065285 Enhanced NA NA 180000 "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "HPA065285: AB_2685454" "prognostic favorable (6.11e-5)" "unprognostic (2.17e-2)" "unprognostic (1.65e-2)" "unprognostic (4.27e-2)" "unprognostic (2.93e-2)" "unprognostic (2.67e-2)" "unprognostic (2.78e-2)" "prognostic favorable (3.15e-5)" "unprognostic (4.90e-3)" "unprognostic (1.53e-1)" "unprognostic (5.52e-2)" "unprognostic (3.26e-2)" "unprognostic (1.66e-2)" "unprognostic (1.16e-2)" "unprognostic (3.48e-1)" "unprognostic (1.99e-1)" "unprognostic (1.43e-3)" 11.4 0.1 1.2 4.3 0.7 0.1 11.9 2.4 1.0 15.8 235.9 4.0 2.0 2.1 2.7 2.6 11.4 8.8 11.1 11.3 0.7 2.6 0.9 9.8 1.2 3.0 4.5 4.9 3.2 28.3 3.3 0.1 2.6 9.8 2.9 0.2 25.4 7.0 1.6 6.0 3.1 0.7 1.3 1.0 138.5 0.3 4.4 8.4 13.2 4.3 3.8 12.9 5.3 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.6 0.6 0.2 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.1 0.0 0.0 0.0 2.6 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.3 0.9 7.3 3.4 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.7 2.4 1.0 11.3 0.7 3.0 4.5 2.6 1.3 4.4 0.7 0.3 6.4 20.7 1.3 0.0 0.6 5.1 7.3 4.0 0.0 15.6 11.0 11.4 30.0 41.6 9.2 0.0 0.0 0.2 2.2 1.9 8.0 0.1 15.1 0.3 0.4 4.9 0.0 0.3 0.9 0.0 3.7 26.5 2.2 1.3 11.8 0.0 0.0 0.1 0.0 0.6 1.4 16.2 0.0 0.4 0.3 0.3 0.4 7.2 0.0 0.6 0.0 0.0 0.0 0.1 17.2 0.6 3.0 0.4 10.2 0.1 0.2 81.1 0.0 0.0 24.0 2.4 0.2 0.2 0.6 0.4 0.0 0.4 0.0 2.8 20.4 COL17A1 "BP180, BPAG2" ENSG00000065618 "Collagen type XVII alpha 1 chain" Q9UMD9 10 104031286-104085880 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 580.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 585.7;Basal respiratory cells: 136.0;Basal squamous epithelial cells: 299.9;Distal enterocytes: 211.5;Proximal enterocytes: 108.5;Suprabasal keratinocytes: 139.4" "Cancer enriched" "Detected in many" 5 "head and neck cancer: 227.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 204.3;HaCaT: 463.8;HBEC3-KT: 745.8;hTCEpi: 914.1;hTERT-HME1: 783.7" "Region enriched" "Detected in single" 4 "cerebellum: 1.0" "Low region specificity" "Detected in many" "HPA043673, HPA052963" Enhanced Supported "Golgi apparatus,Plasma membrane" "Secreted to extracellular matrix" NA NA 32000 "Cluster 1: Neutrophils - Mixed function" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Golgi apparatus" "HPA043673: AB_10960893, HPA052963: AB_2681999" "prognostic favorable (1.38e-4)" "unprognostic (1.33e-1)" "unprognostic (4.01e-1)" "unprognostic (1.01e-1)" "unprognostic (9.65e-2)" "unprognostic (3.75e-1)" "unprognostic (2.13e-1)" "unprognostic (6.82e-3)" "unprognostic (1.63e-1)" "unprognostic (7.85e-3)" "prognostic unfavorable (1.86e-4)" "unprognostic (2.12e-1)" "unprognostic (1.71e-1)" "unprognostic (1.14e-1)" "unprognostic (1.23e-1)" "unprognostic (3.75e-2)" "unprognostic (8.35e-2)" 1.5 0.4 0.8 6.6 1.1 12.2 37.3 1.0 1.4 50.1 0.6 37.4 10.7 0.6 6.6 116.6 1.1 0.3 0.5 0.5 0.6 0.3 0.3 0.9 0.1 0.6 0.7 0.2 0.4 0.0 1.2 35.4 0.6 17.9 27.3 0.0 82.2 9.6 0.5 580.3 37.2 1.0 0.5 2.3 19.8 25.4 0.6 42.7 5.1 0.0 19.8 9.9 102.0 0.8 26.3 0.4 1.5 0.2 0.1 0.0 80.6 0.5 0.3 0.1 0.2 0.3 204.3 0.0 5.1 0.3 3.9 463.8 0.7 745.8 0.7 0.0 0.7 0.0 0.3 0.2 0.1 0.0 0.4 0.7 914.1 0.5 783.7 0.2 3.5 0.1 0.1 0.9 0.0 0.0 0.0 0.3 1.7 5.1 2.6 0.0 0.0 0.3 35.9 26.4 0.2 0.3 0.0 0.2 0.9 4.0 0.2 0.0 1.5 0.5 5.0 0.3 5.5 0.1 0.0 0.0 1.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.8 1.1 1.0 1.4 0.5 0.6 0.6 0.7 0.6 0.5 0.6 0.8 1.0 0.0 1.1 0.7 0.3 585.7 17.7 136.0 299.9 0.6 1.7 85.5 1.1 0.0 16.5 0.0 0.0 10.2 0.3 211.5 0.0 0.8 14.2 23.7 2.3 3.7 2.4 0.0 0.1 0.9 18.9 2.4 23.0 8.1 0.0 0.1 0.0 0.0 1.3 0.0 0.2 5.7 6.1 0.0 28.9 3.6 0.3 0.7 33.8 0.0 0.0 0.4 0.0 0.0 0.4 78.8 35.7 0.7 1.4 16.6 108.5 0.1 5.9 0.4 0.0 0.4 3.0 22.7 1.5 31.9 139.4 5.6 1.3 0.1 21.6 10.7 CPA2 ENSG00000158516 "Carboxypeptidase A2" P48052 7 130266863-130289798 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 416 "pancreas: 45360.2" "Cell type enriched" "Detected in some" 10 "Exocrine glandular cells: 4973.8" "Cancer enriched" "Detected in many" 60 "pancreatic cancer: 411.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 2.2;CACO-2: 3.8;RH-30: 3.0;SCLC-21H: 1.6" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA020342, HPA021317" Enhanced Approved "Golgi apparatus" "Secreted to digestive system" NA NA 1500000 "Cluster 25: Pancreas - Digestion" "Cluster 39: CACO-2 - Unknown function" "Cluster 1: Pancreatic cells - Digestion" "Golgi apparatus" "HPA020342: AB_1846007, HPA021317: AB_1846008" "unprognostic (1.12e-1)" "unprognostic (3.97e-1)" "unprognostic (4.21e-2)" "unprognostic (1.82e-2)" "unprognostic (1.38e-1)" "unprognostic (6.76e-2)" "unprognostic (4.65e-2)" "unprognostic (1.08e-1)" "unprognostic (1.40e-1)" "unprognostic (1.84e-1)" "unprognostic (2.66e-1)" "unprognostic (3.84e-5)" "unprognostic (7.52e-2)" "unprognostic (1.42e-1)" "unprognostic (7.12e-2)" "unprognostic (8.48e-2)" 5.5 1.0 0.3 0.7 0.8 0.4 2.6 1.0 0.9 1.9 0.2 1.3 17.4 0.8 0.1 1.5 0.7 0.0 8.4 0.3 0.6 0.9 2.6 0.7 1.4 2.8 1.3 19.7 45360.2 0.0 1.4 3.2 2.5 1.5 0.4 0.8 7.8 0.0 0.8 1.1 30.6 0.0 1.2 1.2 108.9 2.2 1.1 0.1 0.6 0.0 0.0 0.5 0.8 3.1 0.0 0.0 0.4 2.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 3.8 0.0 0.0 0.5 0.0 0.3 0.0 0.7 0.0 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.2 0.0 3.0 0.0 0.0 0.3 1.6 0.0 0.1 0.0 1.0 0.1 0.0 0.1 0.0 0.0 0.6 0.4 0.3 0.0 0.4 0.1 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.8 1.0 0.9 0.3 0.6 2.8 1.3 2.5 1.2 1.1 3.1 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.6 1.9 8.1 4.3 0.0 0.0 0.9 0.0 0.0 0.1 4973.8 0.0 0.2 4.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.5 0.0 0.0 0.0 10.5 0.3 0.5 0.0 0.0 13.9 4.6 0.0 0.5 1.0 471.3 52.9 0.0 0.0 0.0 9.9 0.0 0.0 0.3 0.0 0.0 1.3 0.4 2.0 0.0 0.1 0.3 0.0 0.2 1.5 0.2 CYP2C18 "CPCI, CYP2C, CYP2C17, P450IIC17" ENSG00000108242 "Cytochrome P450 family 2 subfamily C member 18" P33260 10 94683729-94736190 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 102.8;liver: 197.0;stomach 1: 67.2" "Cell type enhanced" "Detected in some" "Gastric mucus-secreting cells: 68.8;Hepatocytes: 124.0;Proximal enterocytes: 62.5;Squamous epithelial cells: 22.8" "Cancer enhanced" "Detected in many" "liver cancer: 18.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 3.2;OE19: 1.9" "Not detected" "Not detected" HPA074424 Uncertain "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 2: Hepatocytes - Metabolism" Vesicles "Plasma membrane" "HPA074424: " "unprognostic (2.40e-1)" "unprognostic (1.75e-2)" "unprognostic (2.69e-1)" "unprognostic (1.10e-2)" "unprognostic (1.32e-2)" "unprognostic (2.57e-1)" "unprognostic (2.71e-1)" "unprognostic (9.78e-2)" "unprognostic (2.28e-1)" "unprognostic (4.22e-3)" "unprognostic (1.62e-3)" "unprognostic (1.29e-1)" "unprognostic (1.08e-1)" "unprognostic (6.81e-3)" 0.3 0.0 0.0 1.6 0.1 0.0 0.3 0.2 0.1 5.3 0.0 5.9 102.8 0.1 0.0 30.9 0.0 16.3 0.0 0.1 0.0 0.3 197.0 0.8 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 2.5 0.0 5.4 0.0 0.0 4.4 83.1 0.1 0.1 0.0 67.2 0.1 0.1 0.3 0.0 0.0 7.1 0.2 9.5 0.2 0.0 0.1 0.0 0.1 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 1.9 0.0 0.0 0.0 0.4 0.2 0.1 0.1 0.2 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.2 0.0 0.1 0.1 0.1 0.2 0.0 0.0 3.3 0.0 0.3 0.1 0.0 1.6 0.0 0.0 0.0 0.1 0.1 17.2 3.2 0.0 0.0 0.1 0.0 6.7 0.0 1.5 0.0 0.6 0.1 0.0 0.0 2.7 0.5 6.9 0.2 0.1 68.8 1.3 0.0 0.0 1.8 124.0 0.0 0.0 0.8 2.1 2.0 2.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 9.1 3.9 0.0 0.3 0.0 62.5 0.0 0.9 0.0 0.0 0.0 0.1 0.1 0.3 22.8 1.7 1.5 0.1 0.1 5.7 0.0 CYP2C19 "CPCJ, CYP2C, P450IIC19" ENSG00000165841 "Cytochrome P450 family 2 subfamily C member 19" P33261 10 94762681-94855547 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 190.2" "Group enriched" "Detected in some" 11 "Gastric mucus-secreting cells: 3.1;Hepatocytes: 9.5;Proximal enterocytes: 8.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA015066, HPA074424" Supported Uncertain Vesicles "Intracellular and membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 2: Hepatocytes - Metabolism" Vesicles "HPA015066: AB_1847433, HPA074424: " "unprognostic (3.15e-2)" "unprognostic (2.13e-1)" "unprognostic (2.48e-1)" "unprognostic (1.83e-2)" "unprognostic (1.53e-1)" 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.3 0.2 0.2 0.1 0.2 32.4 0.0 0.1 1.6 0.0 1.7 0.0 0.1 0.0 0.0 190.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.6 13.9 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.4 0.2 0.1 0.1 0.0 0.0 0.1 0.1 0.3 0.2 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.0 3.1 0.0 0.0 0.0 0.4 9.5 0.0 0.0 0.6 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 DDIAS "C11orf82, FLJ25416, FLJ38838, noxin" ENSG00000165490 "DNA damage induced apoptosis suppressor" Q8IXT1 11 82899975-82958277 "Predicted intracellular proteins" "Apoptosis, Cell cycle, Growth arrest" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 7.9;testis: 10.8" "Cell type enhanced" "Detected in many" "Plasma cells: 8.2;Spermatocytes: 17.2;Spermatogonia: 18.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA038540, HPA038541" Approved Approved "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Cytosol" "HPA038540: AB_10672648, HPA038541: AB_2676071" "unprognostic (2.53e-1)" "unprognostic (2.27e-1)" "unprognostic (5.04e-3)" "unprognostic (1.25e-2)" "unprognostic (1.20e-1)" "unprognostic (5.32e-2)" "unprognostic (3.86e-6)" "unprognostic (4.65e-3)" "unprognostic (1.01e-3)" "unprognostic (8.24e-3)" "unprognostic (2.04e-4)" "unprognostic (4.72e-2)" "unprognostic (1.11e-16)" "unprognostic (7.17e-3)" "unprognostic (9.59e-2)" "unprognostic (1.89e-1)" "unprognostic (9.13e-2)" 0.9 0.4 0.6 3.3 0.9 7.9 2.1 0.9 1.0 0.7 0.4 1.8 1.6 1.2 1.0 2.9 0.5 0.7 0.5 0.8 0.4 0.4 1.2 3.4 4.4 0.8 0.8 0.5 0.9 0.1 0.1 1.9 0.7 0.5 2.2 0.5 0.8 0.4 1.0 2.2 1.5 1.8 0.5 2.9 0.9 10.8 0.8 5.3 0.4 0.9 6.2 3.5 0.9 1.8 13.6 22.6 21.0 15.2 1.9 3.1 15.3 25.4 10.5 26.8 31.0 22.4 16.2 16.1 36.1 5.7 21.6 24.7 36.0 15.5 36.8 30.7 19.7 23.1 10.6 9.1 0.2 28.6 19.7 0.7 1.4 33.8 15.6 2.3 12.8 20.5 23.9 27.0 23.9 19.6 27.0 23.2 25.1 36.5 24.4 20.0 40.5 20.6 5.7 23.3 15.6 21.5 15.2 15.6 5.7 20.2 16.5 11.7 6.0 26.7 35.9 71.1 30.4 15.4 44.3 56.4 8.4 20.2 26.3 0.7 10.3 4.1 0.5 7.9 0.2 1.1 0.3 0.7 4.5 1.7 0.6 0.4 5.5 2.2 8.5 1.4 0.5 3.2 0.6 0.9 0.9 1.0 0.8 0.4 0.8 0.8 0.7 0.5 0.8 1.8 0.3 0.0 0.0 0.0 4.3 0.0 0.6 0.0 1.8 0.0 1.1 1.1 0.9 1.5 0.0 0.0 0.0 2.7 1.0 0.6 0.0 0.9 4.2 1.0 0.6 0.8 0.0 6.5 0.6 0.6 5.5 0.8 1.1 1.2 0.0 2.5 0.7 0.7 2.5 0.0 0.3 0.7 0.0 6.4 0.0 1.9 0.3 3.5 0.0 1.9 4.5 0.0 4.1 0.5 0.6 0.5 0.1 0.7 8.2 0.7 0.3 0.3 0.0 0.0 0.0 0.8 1.1 17.2 18.2 5.4 0.0 0.3 1.5 0.5 1.6 0.9 DLGAP5 "DLG1, DLG7, HURP, KIAA0008" ENSG00000126787 "DLG associated protein 5" Q15398 14 55148112-55191608 "Plasma proteins, Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 29.7;lymphoid tissue: 42.0;testis: 17.4" "Cell type enhanced" "Detected in many" "Erythroid cells: 92.6;Extravillous trophoblasts: 23.1;Plasma cells: 22.1;Spermatocytes: 68.1;Spermatogonia: 31.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "T-reg: 5.4" "Lineage enriched" "Detected in many" 5 "T-cells: 5.4" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA005546 Enhanced Supported "Centriolar satellite,Cytosol" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Centriolar satellite, Cytosol" "HPA005546: AB_1078677" "unprognostic (2.24e-1)" "unprognostic (1.77e-1)" "unprognostic (1.19e-3)" "prognostic unfavorable (4.59e-4)" "unprognostic (1.42e-1)" "unprognostic (1.66e-2)" "prognostic unfavorable (1.52e-6)" "prognostic unfavorable (7.85e-4)" "unprognostic (6.15e-3)" "unprognostic (3.55e-1)" "prognostic unfavorable (9.94e-6)" "unprognostic (4.69e-2)" "unprognostic (0.00e+0)" "unprognostic (1.06e-2)" "unprognostic (3.64e-1)" "unprognostic (1.29e-1)" "unprognostic (1.93e-2)" 0.8 0.3 1.4 8.1 0.9 29.7 1.4 0.4 1.8 0.8 0.6 5.5 5.0 1.3 0.1 5.2 0.4 0.8 0.2 1.0 1.7 0.2 0.7 0.7 17.9 0.7 1.0 0.2 0.1 0.2 0.0 4.1 0.8 0.2 6.7 0.1 0.8 0.1 0.1 3.1 4.6 2.7 0.3 2.6 3.0 17.4 1.1 42.0 0.4 0.0 18.7 2.0 1.5 3.8 144.8 56.8 140.6 63.7 3.3 13.4 43.8 80.3 52.7 115.3 109.3 45.9 75.8 82.1 44.2 46.9 47.4 85.6 91.5 64.0 150.5 101.9 45.7 84.4 49.9 39.3 0.4 82.7 49.3 2.8 2.2 54.8 27.0 18.9 129.0 82.5 70.5 79.8 109.3 69.2 105.0 42.7 72.6 63.3 57.3 80.8 137.9 39.0 37.9 45.2 71.7 40.7 84.8 31.7 30.8 60.6 71.6 31.6 49.6 52.4 133.3 50.6 94.6 19.4 44.9 108.9 35.9 59.6 83.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.9 1.4 0.3 0.0 0.2 0.1 0.2 1.0 0.0 0.0 5.4 0.7 1.4 0.9 0.4 1.8 1.0 1.7 0.7 1.0 0.8 0.3 1.1 3.8 0.1 0.0 0.5 0.0 4.4 1.1 0.7 3.3 0.0 0.0 1.2 0.9 0.4 0.0 1.3 0.0 0.0 11.6 1.4 3.2 0.0 0.4 19.7 7.2 2.6 2.4 0.0 92.6 0.3 0.0 23.1 4.2 7.7 4.5 0.0 15.8 3.9 0.5 10.5 0.0 0.3 3.6 8.2 4.1 1.6 6.0 0.9 3.7 0.0 0.0 0.0 0.0 1.0 0.0 0.3 0.2 0.2 1.2 22.1 0.6 0.3 0.1 1.3 0.0 6.6 0.0 3.8 68.1 31.7 11.6 0.4 1.9 4.0 0.9 6.9 1.4 DNM2 "CMT2M, CMTDI1, CMTDIB, DI-CMTB, DYN2, DYNII" ENSG00000079805 "Dynamin 2" P50570 19 10718079-10833488 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Endocytosis, Phagocytosis" "Hydrolase, Motor protein" "Cancer-related genes, Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 242.8;Paneth cells: 177.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054246 Supported Approved "Golgi apparatus,Cytosol" NA NA 230000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus, Cytosol" "HPA054246: AB_2682427" "unprognostic (2.30e-1)" "unprognostic (5.23e-2)" "unprognostic (4.72e-2)" "unprognostic (1.23e-1)" "unprognostic (1.76e-1)" "prognostic favorable (8.91e-4)" "prognostic unfavorable (3.63e-4)" "unprognostic (1.03e-1)" "unprognostic (3.79e-1)" "unprognostic (1.89e-1)" "unprognostic (4.75e-2)" "unprognostic (5.35e-2)" "unprognostic (5.47e-2)" "unprognostic (5.40e-3)" "unprognostic (2.68e-1)" "unprognostic (1.61e-1)" "unprognostic (1.99e-3)" 55.1 69.9 50.5 63.2 77.8 125.7 46.1 74.1 64.1 49.0 38.8 105.8 65.9 42.2 25.3 67.6 42.5 40.5 87.2 52.3 57.4 72.8 57.2 87.0 62.4 82.7 78.9 36.6 68.2 38.9 41.9 51.3 79.8 47.4 83.9 30.7 55.0 55.7 108.1 92.8 99.6 35.1 60.3 81.0 98.6 55.1 72.9 58.6 47.6 82.8 65.4 64.6 54.5 101.6 116.4 92.8 67.6 54.6 67.6 65.4 86.5 75.1 70.5 108.8 91.7 94.2 74.7 83.2 132.2 81.5 52.5 99.4 92.6 82.1 90.8 103.1 72.4 160.1 81.7 107.1 82.9 87.8 146.5 67.8 62.4 83.5 77.9 66.2 107.3 84.9 131.5 139.1 68.0 140.1 126.3 85.7 76.6 138.3 109.7 125.6 72.6 95.7 71.3 171.1 97.1 63.8 86.6 73.6 54.2 74.9 58.8 106.2 99.6 120.7 40.5 172.0 102.7 112.7 127.3 77.9 89.9 134.0 61.0 3.5 3.5 7.0 4.0 6.2 3.8 2.5 3.0 4.4 4.2 2.1 1.7 3.0 6.5 8.9 8.4 8.4 3.8 4.1 50.5 77.8 74.1 64.1 52.3 57.4 82.7 78.9 79.8 60.3 72.9 101.6 37.8 32.1 22.3 24.8 48.8 23.2 17.1 13.8 22.2 28.8 19.7 16.3 30.3 14.3 25.7 51.5 22.9 25.7 57.2 242.8 50.9 35.2 48.4 32.2 17.9 33.1 21.6 38.1 29.2 32.0 106.9 19.5 168.7 39.7 19.0 36.8 20.3 22.8 49.1 43.7 31.1 106.9 14.2 28.0 39.6 98.0 16.8 55.2 19.6 60.9 43.4 17.2 39.1 23.1 90.9 45.2 177.3 27.8 92.2 20.2 90.7 38.8 18.0 26.3 26.3 18.7 27.6 15.0 12.3 26.6 31.5 31.7 46.4 40.7 82.5 22.8 E2F1 "RBBP3, RBP3" ENSG00000101412 "E2F transcription factor 1" Q01094 20 33675477-33686385 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Apoptosis, Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 34.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 25.0;Granulosa cells: 11.4;Spermatogonia: 32.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.0" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB000329, HPA008003, CAB019308, HPA029735" Enhanced Supported Nucleoplasm,Centrosome NA Yes "Cluster 22: NK-cells - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Centrosome" "CAB000329: AB_627476, CAB019308: , HPA008003: AB_1847936, HPA029735: AB_2673176" "unprognostic (7.46e-2)" "prognostic favorable (9.22e-6)" "unprognostic (2.11e-2)" "prognostic unfavorable (4.33e-5)" "unprognostic (1.51e-1)" "unprognostic (1.21e-2)" "prognostic unfavorable (3.83e-5)" "unprognostic (1.25e-2)" "unprognostic (8.23e-2)" "unprognostic (9.66e-2)" "prognostic unfavorable (4.18e-4)" "unprognostic (3.15e-2)" "prognostic unfavorable (8.99e-5)" "unprognostic (1.05e-2)" "unprognostic (7.50e-2)" "prognostic favorable (1.62e-4)" "unprognostic (1.91e-1)" 1.8 5.5 7.1 5.6 7.1 34.3 1.6 5.2 9.2 1.8 3.9 3.8 3.2 1.2 0.2 5.7 1.3 0.7 1.4 6.1 5.6 0.9 1.8 3.7 8.7 7.6 6.4 3.5 1.0 1.3 0.6 2.4 6.5 1.9 3.9 0.7 1.9 0.9 1.6 4.7 4.1 2.8 7.0 5.0 3.7 10.4 6.9 10.7 0.8 0.8 6.9 2.4 2.5 8.3 48.1 45.4 52.0 40.5 5.2 3.6 39.3 45.0 21.4 55.9 46.7 81.1 48.0 87.3 44.2 20.2 67.7 35.4 25.3 23.8 24.8 26.4 36.5 71.6 71.9 47.7 0.4 34.0 43.6 2.8 1.4 30.6 5.4 5.7 14.6 54.4 19.3 60.0 34.9 42.3 72.8 71.6 15.6 47.9 64.6 71.4 140.7 36.2 9.6 28.7 76.7 54.1 54.6 37.6 22.7 14.8 47.3 42.4 7.9 65.0 37.7 45.8 64.8 58.1 42.0 72.6 54.1 20.0 39.3 0.0 0.0 0.1 0.0 0.2 0.0 0.5 0.1 0.1 0.0 0.0 0.0 0.3 0.0 0.4 1.0 0.1 0.1 0.1 7.1 7.1 5.2 9.2 6.1 5.6 7.6 6.4 6.5 7.0 6.9 8.3 1.1 0.0 1.1 0.7 3.6 2.9 1.7 0.5 0.0 2.3 3.1 4.3 0.4 0.0 1.4 0.0 0.0 5.0 2.9 2.4 0.0 0.9 1.0 0.3 1.0 1.6 0.0 25.0 1.5 0.2 9.6 3.0 7.7 1.2 0.0 11.4 0.7 0.8 4.4 0.0 0.5 4.6 2.0 0.6 2.1 3.1 2.1 3.1 1.8 1.0 0.1 1.5 1.0 1.0 3.4 0.6 0.5 1.2 9.7 0.5 1.4 0.1 0.2 2.3 0.0 1.0 3.0 7.5 32.9 3.7 1.7 1.8 3.3 1.2 7.0 3.5 E2F7 ENSG00000165891 "E2F transcription factor 7" Q96AV8 12 77021248-77065569 "Predicted intracellular proteins, Transcription factors" "Cell cycle, DNA damage, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.0;lymphoid tissue: 8.3" "Cell type enhanced" "Detected in many" "Early spermatids: 46.9;Endometrial ciliated cells: 17.2;Late spermatids: 70.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.7" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "midbrain: 5.8;pons: 6.4;thalamus: 11.3" HPA064866 Supported "Nuclear speckles" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" "Nuclear speckles" "HPA064866: AB_2685374" "unprognostic (1.21e-1)" "unprognostic (8.92e-2)" "unprognostic (7.39e-2)" "unprognostic (7.27e-2)" "unprognostic (1.54e-1)" "unprognostic (3.80e-2)" "unprognostic (6.14e-5)" "unprognostic (1.05e-3)" "unprognostic (1.72e-1)" "unprognostic (3.57e-2)" "unprognostic (5.67e-5)" "unprognostic (1.42e-1)" "unprognostic (0.00e+0)" "unprognostic (3.05e-2)" "unprognostic (1.57e-1)" "unprognostic (1.00e-1)" "unprognostic (2.51e-1)" 0.2 0.1 0.2 1.1 0.2 5.0 0.2 0.0 0.3 0.3 0.3 0.9 0.7 0.2 0.0 1.4 0.6 0.7 0.2 0.2 0.2 0.1 0.2 0.3 1.5 0.7 0.8 0.1 0.2 0.1 0.5 1.0 0.4 0.2 1.5 0.2 0.2 0.1 0.0 1.1 0.8 0.3 0.6 0.3 0.6 2.9 0.2 8.3 0.1 0.1 1.6 0.6 0.5 0.2 20.1 9.4 25.7 10.1 0.8 2.5 31.1 27.6 29.8 14.2 17.0 12.8 6.6 11.2 5.4 5.5 29.5 15.1 15.5 29.8 27.1 4.4 10.4 9.8 27.3 7.3 5.9 8.5 8.8 0.8 7.7 37.4 22.9 8.3 14.2 19.0 10.4 8.9 29.5 10.1 31.9 0.1 18.1 6.7 21.9 23.0 22.2 6.2 3.5 16.8 16.3 10.7 22.9 7.9 6.5 10.9 12.6 8.7 39.3 53.5 26.8 23.0 36.7 9.5 5.8 7.1 19.3 3.8 34.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.7 0.4 0.0 0.2 0.2 0.0 0.3 0.2 0.2 0.7 0.8 0.4 0.6 0.2 0.2 0.1 0.0 0.5 2.3 0.5 0.3 1.0 1.4 4.6 0.0 0.6 0.9 2.1 0.0 2.2 0.0 0.0 1.8 0.4 1.5 0.0 0.3 46.9 17.2 0.8 1.5 0.0 7.4 0.4 1.1 3.1 0.8 6.1 3.1 4.5 6.3 0.0 0.0 0.9 0.0 0.2 1.2 2.0 0.3 1.2 70.2 0.3 1.3 0.0 3.7 0.0 1.6 0.0 0.5 0.0 12.0 0.1 0.7 6.9 1.7 0.0 0.0 3.1 0.1 0.0 0.0 1.2 1.2 2.1 6.3 0.6 0.3 0.8 0.4 2.1 4.3 ECT2 ARHGEF31 ENSG00000114346 "Epithelial cell transforming 2" Q9H8V3 3 172750682-172821474 "Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Neurogenesis, Protein transport, Transport" "Guanine-nucleotide releasing factor" Oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 64.6;Spermatocytes: 42.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA036363, HPA053261" Enhanced Nucleoplasm,Cytosol No Yes "Cluster 1: Neutrophils - Mixed function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "HPA036363: AB_2732472, HPA053261: AB_2682094" "unprognostic (3.83e-2)" "unprognostic (4.34e-1)" "unprognostic (1.27e-2)" "unprognostic (4.22e-3)" "unprognostic (4.49e-2)" "unprognostic (5.02e-3)" "prognostic unfavorable (6.82e-6)" "prognostic unfavorable (1.13e-4)" "unprognostic (1.82e-2)" "unprognostic (1.01e-1)" "prognostic unfavorable (2.24e-5)" "unprognostic (2.44e-2)" "prognostic unfavorable (1.19e-5)" "unprognostic (1.08e-2)" "unprognostic (1.46e-1)" "unprognostic (1.29e-1)" "unprognostic (1.33e-1)" 3.6 3.3 2.1 8.2 1.9 19.8 7.5 3.4 3.4 8.1 1.4 11.5 9.3 4.4 1.8 8.9 3.3 5.3 3.2 2.4 1.4 4.3 2.6 5.2 10.5 2.1 1.7 1.3 2.9 3.6 1.2 8.8 2.7 3.2 15.8 12.5 5.6 2.6 2.1 7.1 7.6 7.5 0.7 4.3 9.4 15.9 2.3 23.3 3.9 2.7 11.4 6.9 4.2 3.5 192.0 133.6 103.2 54.0 10.6 21.8 51.6 81.5 67.5 121.4 116.9 74.7 196.9 47.2 122.1 48.8 116.0 81.8 84.2 53.1 164.3 67.8 46.6 29.6 70.0 38.5 4.6 46.2 32.8 7.1 9.0 72.2 73.2 34.0 53.0 68.6 31.3 67.2 97.2 67.6 47.5 34.6 84.4 156.7 72.0 33.7 101.1 60.7 92.2 43.7 68.6 44.1 104.5 117.4 42.2 51.5 195.4 34.1 46.5 58.5 55.7 79.6 174.9 32.8 47.2 88.2 51.6 39.7 78.0 6.0 2.0 0.7 1.0 1.7 1.1 1.4 1.4 0.9 1.6 1.3 0.6 0.9 6.3 0.7 0.7 1.6 2.5 0.7 2.1 1.9 3.4 3.4 2.4 1.4 2.1 1.7 2.7 0.7 2.3 3.5 6.7 6.4 3.2 4.2 3.8 19.5 4.9 6.2 9.1 3.4 10.1 6.5 3.6 5.7 5.7 3.7 64.6 12.0 2.9 10.7 0.0 9.5 3.3 20.1 6.6 7.7 4.8 25.2 6.5 9.2 14.9 6.0 17.9 20.5 0.0 17.9 5.3 2.9 7.3 0.0 2.5 13.5 10.2 4.7 6.3 2.8 0.9 5.1 7.2 15.0 2.8 3.1 2.1 3.0 4.9 20.7 3.8 1.5 9.6 12.8 1.5 3.7 11.0 16.3 0.0 2.9 5.2 42.6 30.4 16.9 12.8 3.8 4.1 3.3 13.5 8.8 EME1 "FLJ31364, MMS4L, SLX2A" ENSG00000154920 "Essential meiotic structure-specific endonuclease 1" Q96AY2 17 50373220-50381483 "Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 4.4;epididymis: 6.3;testis: 5.7" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 4.6;Extravillous trophoblasts: 4.8;Granulosa cells: 4.5;Spermatocytes: 13.2;Spermatogonia: 9.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 33 "basophil: 18.6" "Lineage enriched" "Detected in single" 33 "granulocytes: 18.6" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "CAB016127, HPA052188" Supported Approved "Nuclear bodies,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear bodies, Cytosol" "CAB016127: AB_2278026, HPA052188: " "unprognostic (3.81e-1)" "unprognostic (7.72e-2)" "unprognostic (6.49e-2)" "unprognostic (2.45e-3)" "unprognostic (2.74e-1)" "unprognostic (1.94e-2)" "unprognostic (9.94e-5)" "unprognostic (2.87e-2)" "unprognostic (1.07e-2)" "unprognostic (2.02e-2)" "unprognostic (4.37e-3)" "unprognostic (2.83e-3)" "unprognostic (0.00e+0)" "unprognostic (9.82e-2)" "unprognostic (1.26e-1)" "unprognostic (3.71e-1)" "unprognostic (3.41e-1)" 0.5 0.3 0.2 1.7 0.3 4.4 0.6 0.1 0.4 0.5 0.0 0.9 0.8 0.4 6.3 1.1 0.3 0.3 0.2 0.1 0.1 0.2 0.4 0.4 2.3 0.3 0.2 0.5 0.2 0.1 0.1 1.4 0.3 0.2 1.3 0.4 0.5 0.1 0.2 1.1 0.7 0.6 0.1 0.9 0.5 5.7 0.3 3.3 0.2 0.0 2.6 0.4 0.5 0.4 13.9 20.0 26.2 13.7 1.2 2.6 18.8 14.2 5.4 19.3 17.7 31.7 11.0 11.0 18.3 5.7 12.0 10.7 24.5 11.3 27.3 21.7 19.3 26.3 23.3 14.8 0.1 10.9 8.4 0.5 0.8 22.3 9.2 2.6 4.5 31.2 16.3 25.6 11.6 15.2 25.0 13.9 15.1 14.2 13.6 25.5 50.7 15.4 4.3 5.6 10.1 20.2 8.7 4.8 8.1 20.9 16.8 12.3 3.1 24.8 14.9 16.6 19.7 16.0 17.4 10.5 7.8 12.2 15.6 18.6 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.0 0.5 0.0 0.2 0.2 0.3 0.1 0.4 0.1 0.1 0.3 0.2 0.3 0.1 0.3 0.4 0.1 0.0 1.1 0.3 0.8 0.1 0.3 0.5 0.6 1.5 0.5 0.3 0.4 0.0 0.7 0.0 0.0 4.6 0.5 0.6 0.0 0.3 0.5 0.8 0.7 0.4 0.0 3.8 0.1 0.0 4.8 0.8 2.0 0.5 0.0 4.5 0.0 0.3 2.2 0.0 0.1 0.9 0.0 0.0 1.4 0.6 0.6 0.8 0.0 0.0 1.0 0.5 1.0 0.0 0.3 0.1 0.0 0.0 2.5 0.1 0.1 0.0 0.9 0.3 0.0 0.6 1.0 13.2 9.1 1.5 0.1 1.1 0.5 0.6 1.3 0.2 EPAS1 "bHLHe73, HIF2A, HLF, MOP2, PASD2" ENSG00000116016 "Endothelial PAS domain protein 1" Q99814 2 46293667-46386697 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Angiogenesis, Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Congenital erythrocytosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 412.0;placenta: 445.6" "Cell type enhanced" "Detected in many" "Adipocytes: 831.5;Endothelial cells: 425.8;Hepatic stellate cells: 538.7;Syncytiotrophoblasts: 349.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 18 "basophil: 20.6;eosinophil: 8.4" "Lineage enriched" "Detected in single" 26 "granulocytes: 20.6" "Cell line enhanced" "Detected in many" "BEWO: 267.3;BJ hTERT+: 266.7;HHSteC: 326.3;RT4: 339.8;TIME: 337.8;U-138 MG: 284.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031200, HPA069697" Supported Nucleoplasm,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 82: Adipose tissue - ECM organization" "Cluster 15: RT4 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Cytosol "HPA031200: AB_2673785, HPA069697: AB_2732139" "unprognostic (1.74e-1)" "unprognostic (9.47e-2)" "unprognostic (1.29e-2)" "unprognostic (2.74e-1)" "unprognostic (5.25e-2)" "unprognostic (1.75e-1)" "unprognostic (2.22e-2)" "unprognostic (8.67e-2)" "unprognostic (6.00e-2)" "unprognostic (9.72e-2)" "unprognostic (1.55e-2)" "unprognostic (9.29e-2)" "prognostic favorable (2.63e-4)" "unprognostic (6.66e-3)" "unprognostic (7.75e-2)" "unprognostic (7.56e-2)" "unprognostic (1.36e-1)" 296.0 52.1 53.4 66.1 48.6 2.3 166.7 44.6 47.7 72.9 139.1 57.1 46.3 87.9 26.0 72.7 80.1 83.2 122.1 39.2 44.7 89.5 110.1 412.0 47.9 60.5 54.2 34.5 59.6 79.4 25.9 445.6 60.2 51.8 42.6 53.6 40.0 66.3 80.5 42.9 50.9 71.7 45.6 84.6 42.8 20.0 75.4 17.9 138.1 153.6 40.3 94.9 47.8 44.6 32.2 33.5 2.1 2.5 153.8 98.6 267.3 98.7 266.7 55.6 60.1 5.8 5.5 0.1 23.8 188.5 55.2 15.2 0.6 79.0 41.3 0.9 1.6 0.0 10.3 71.8 326.3 0.1 19.8 145.0 106.9 108.7 75.8 41.0 193.1 0.7 3.1 0.2 34.2 27.8 0.9 0.8 1.3 22.4 18.5 1.0 3.7 10.5 34.5 339.8 1.4 68.5 77.4 175.5 21.0 68.3 11.7 14.1 337.8 284.0 8.1 38.3 8.4 0.2 0.2 0.1 207.4 5.4 7.4 20.6 0.1 8.4 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.1 0.1 53.4 48.6 44.6 47.7 39.2 44.7 60.5 54.2 60.2 45.6 75.4 44.6 831.5 76.9 151.7 28.4 4.1 48.2 69.8 108.6 43.9 4.5 27.4 29.5 79.2 32.9 124.9 3.7 10.4 126.2 6.6 112.6 1.9 23.0 12.9 36.1 32.7 425.8 4.2 18.7 1.2 52.4 299.9 76.8 32.1 67.6 41.2 2.3 538.7 78.0 55.5 0.0 1.6 13.9 22.4 60.9 30.3 52.7 12.5 21.4 28.4 155.5 0.6 95.5 0.0 31.2 1.3 26.1 53.7 6.4 3.9 57.8 45.9 30.2 31.7 59.3 282.7 23.3 250.5 1.5 4.6 65.0 33.2 349.7 15.9 4.7 23.6 85.7 ESRRB "DFNB35, ERR2, ERRb, ERRbeta, ESRL2, NR3B2" ENSG00000119715 "Estrogen related receptor beta" O95718 14 76310712-76501837 "Disease related genes, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "retina: 36.5" "Cell type enhanced" "Detected in some" "Distal tubular cells: 13.7;Early spermatids: 14.1;Horizontal cells: 55.5;Late spermatids: 37.6;Rod photoreceptor cells: 40.3" "Cancer enhanced" "Detected in single" "testis cancer: 0.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 1.3;K-562: 5.0;U-266/70: 2.3" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA074772 Supported Nucleoplasm,Cytosol NA NA "Cluster 77: Retina - Visual perception" "Cluster 1: K-562 - Erythropoiesis" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm Cytosol "HPA074772: " "unprognostic (1.12e-1)" "unprognostic (1.34e-2)" "unprognostic (6.28e-2)" "unprognostic (3.92e-5)" "unprognostic (5.18e-2)" "unprognostic (3.15e-2)" "unprognostic (2.14e-1)" "unprognostic (1.48e-1)" "unprognostic (2.28e-2)" "unprognostic (2.24e-2)" "unprognostic (2.16e-2)" "unprognostic (4.11e-2)" "unprognostic (2.68e-1)" "unprognostic (3.46e-1)" "unprognostic (1.89e-1)" "unprognostic (2.12e-4)" "unprognostic (4.40e-2)" 0.0 0.0 0.4 0.0 0.4 0.0 0.3 0.4 0.4 0.0 1.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 4.9 0.3 0.6 6.6 0.0 0.0 0.0 1.5 1.2 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 36.5 0.0 0.0 6.5 0.0 0.0 0.0 0.6 0.1 2.4 1.2 0.9 0.1 0.0 1.6 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.2 0.0 0.0 0.0 0.3 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 5.0 0.2 0.0 0.6 0.0 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.5 0.0 0.4 0.0 0.2 2.3 0.7 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.4 0.4 0.3 0.6 1.5 1.2 0.7 0.6 0.9 0.8 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 2.4 1.0 0.4 5.8 0.0 0.0 0.0 2.1 0.0 0.0 0.0 13.7 0.0 14.1 0.0 0.0 0.8 0.0 0.0 1.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.5 2.0 0.0 0.0 0.0 0.0 37.6 0.0 0.1 0.0 3.7 0.0 4.6 0.0 1.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 40.3 0.0 0.1 0.8 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FAM111B CANP ENSG00000189057 "Family with sequence similarity 111 member B" Q6SJ93 11 59107185-59127412 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Hydrolase, Protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 18.0" "Cell type enhanced" "Detected in many" "B-cells: 12.8;Erythroid cells: 9.1;Plasma cells: 8.8;Squamous epithelial cells: 7.1;Undifferentiated cells: 10.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "memory B-cell: 3.3;naive B-cell: 2.6" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" HPA038637 Uncertain Approved Nucleoplasm,Cytosol No Yes "Cluster 37: B-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 55: Plasma cells - Humoral immune response" Nucleoplasm Cytosol "HPA038637: AB_10672522" "unprognostic (2.31e-1)" "unprognostic (2.68e-2)" "unprognostic (1.80e-3)" "unprognostic (6.94e-2)" "unprognostic (1.89e-1)" "unprognostic (1.96e-2)" "prognostic unfavorable (1.76e-4)" "unprognostic (1.49e-3)" "unprognostic (1.40e-2)" "unprognostic (4.85e-2)" "prognostic unfavorable (1.17e-5)" "unprognostic (1.01e-2)" "unprognostic (1.24e-5)" "unprognostic (2.94e-2)" "unprognostic (1.80e-1)" "unprognostic (1.20e-3)" "unprognostic (1.24e-1)" 0.9 0.5 0.5 5.9 0.6 4.8 2.7 2.8 1.8 1.0 0.1 5.6 3.4 1.0 0.5 3.4 0.5 0.8 0.3 0.6 1.1 0.4 2.5 1.1 12.3 0.5 1.0 0.2 0.6 0.9 0.0 1.7 0.7 1.0 5.8 1.3 0.8 0.4 0.4 4.4 4.0 2.0 0.1 1.8 3.2 0.8 0.6 18.0 0.9 0.1 13.3 1.7 1.0 2.1 72.6 18.5 26.6 0.4 2.7 4.9 0.3 53.5 26.7 31.2 46.1 38.7 28.0 89.8 35.4 15.7 26.3 54.7 39.5 36.2 55.2 46.8 9.5 9.8 32.3 16.9 0.1 0.3 11.1 1.2 1.2 30.3 2.4 6.0 16.9 24.1 2.8 81.9 37.2 27.3 57.7 0.6 0.3 43.2 21.0 60.1 39.7 34.7 16.8 61.2 5.2 16.9 44.4 50.8 8.7 9.7 56.2 5.0 9.4 24.1 52.4 73.5 49.6 62.6 48.4 0.6 35.0 0.4 35.4 0.2 0.1 0.1 0.1 0.0 0.1 3.3 0.2 0.3 0.1 2.6 0.1 0.1 1.6 0.0 0.1 0.1 0.7 0.1 0.5 0.6 2.8 1.8 0.6 1.1 0.5 1.0 0.7 0.1 0.6 2.1 0.7 0.0 0.0 0.0 12.8 4.2 2.2 4.2 1.8 0.0 2.5 4.2 0.3 0.0 1.4 0.0 0.0 1.1 1.4 4.0 0.0 0.8 0.0 0.9 1.6 1.2 0.0 9.1 0.0 0.0 0.4 1.5 3.6 1.9 0.0 6.3 0.0 0.2 3.9 0.0 0.0 4.4 2.0 0.3 1.6 0.0 0.0 2.4 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.6 1.3 0.0 8.8 0.7 0.5 0.1 1.6 0.0 0.0 1.3 1.8 0.1 1.0 7.1 2.7 0.1 3.2 1.1 10.4 1.6 FAM177B "FLJ43505, RP11-452F19.2" ENSG00000197520 "Family with sequence similarity 177 member B" A6PVY3 1 222737207-222750805 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "stomach 1: 49.6" "Cell type enhanced" "Detected in some" "B-cells: 22.8;Cardiomyocytes: 19.0;Gastric mucus-secreting cells: 53.5;Intestinal goblet cells: 58.6;Microglial cells: 32.8" "Cancer enhanced" "Detected in many" "pancreatic cancer: 3.1" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 20 "memory B-cell: 40.9;naive B-cell: 53.6" "Lineage enriched" "Detected in many" 22 "B-cells: 53.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA063059 Uncertain NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 4: Stomach - Digestion" "Cluster 27: Mucus-secreting cells - Mucin production" "HPA063059: AB_2684933" "unprognostic (8.19e-2)" "unprognostic (1.72e-1)" "unprognostic (4.88e-3)" "unprognostic (3.09e-2)" "unprognostic (7.70e-3)" "unprognostic (1.57e-3)" "unprognostic (2.65e-2)" "unprognostic (1.03e-2)" "unprognostic (1.48e-1)" "unprognostic (2.37e-1)" "unprognostic (1.66e-1)" "unprognostic (2.93e-3)" "unprognostic (1.56e-6)" "unprognostic (5.13e-1)" "unprognostic (1.09e-1)" "unprognostic (1.79e-2)" "unprognostic (4.29e-2)" 0.2 1.6 1.2 3.1 0.5 0.2 0.3 0.1 0.7 0.3 0.0 6.7 4.9 0.2 0.2 0.3 0.2 10.1 0.2 1.1 0.6 0.2 0.1 0.4 8.4 1.9 0.8 0.1 0.2 0.2 0.2 2.5 0.9 0.4 9.3 0.1 8.6 0.2 0.0 0.0 12.2 0.9 0.5 2.2 49.6 1.8 1.3 1.0 0.2 0.0 8.3 0.7 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.4 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 40.9 0.0 0.0 0.1 53.6 0.0 0.1 0.8 0.0 0.1 2.4 0.0 1.4 1.2 0.5 0.1 0.7 1.1 0.6 1.9 0.8 0.9 0.5 1.3 0.7 0.1 0.0 0.0 0.7 22.8 0.4 0.8 0.3 0.0 0.0 0.5 0.3 19.0 8.6 0.3 0.0 0.0 0.0 1.4 1.1 0.0 0.3 8.6 0.1 0.1 0.7 0.0 0.4 0.8 0.4 0.0 1.5 53.5 0.5 0.0 0.0 0.0 0.0 0.8 0.0 0.8 58.6 0.0 1.9 0.8 11.9 0.0 3.5 0.0 32.8 0.1 0.0 0.0 1.0 0.2 0.2 0.1 0.0 0.1 2.2 3.0 0.1 0.1 0.0 0.0 1.2 0.8 0.4 0.3 0.2 0.1 0.0 0.9 0.0 1.0 0.5 FAM222A "C12orf34, FLJ14721" ENSG00000139438 "Family with sequence similarity 222 member A" Q5U5X8 12 109713825-109770495 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 65.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 33.3;Early spermatids: 29.1;Horizontal cells: 77.4;Oligodendrocytes: 78.5;Rod photoreceptor cells: 50.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 4 "SH-SY5Y: 116.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040181, HPA075616" Uncertain Approved "Golgi apparatus,Cell Junctions,Midbody ring" Yes NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 46: Photoreceptor cells - Phototransduction" "Golgi apparatus" "Cell Junctions, Midbody ring" "HPA040181: AB_10796448, HPA075616: " "unprognostic (8.59e-3)" "prognostic favorable (1.82e-5)" "unprognostic (1.43e-1)" "unprognostic (1.57e-1)" "unprognostic (1.92e-1)" "unprognostic (2.05e-2)" "unprognostic (1.46e-2)" "unprognostic (1.03e-1)" "unprognostic (6.66e-2)" "unprognostic (8.17e-2)" "prognostic favorable (4.81e-4)" "unprognostic (1.15e-1)" "unprognostic (4.16e-2)" "prognostic favorable (8.59e-4)" "unprognostic (3.93e-2)" "unprognostic (2.77e-1)" "unprognostic (1.24e-1)" 0.7 19.0 23.7 0.7 45.2 0.6 1.2 36.7 34.2 0.6 5.6 1.9 4.8 0.3 0.8 2.3 0.4 0.8 8.9 20.0 27.6 10.6 4.0 2.1 0.4 41.2 43.1 13.4 3.9 0.7 22.4 0.1 37.7 1.8 1.0 22.1 3.4 0.5 4.3 3.2 2.2 0.4 29.0 6.2 7.2 23.4 48.4 0.4 0.7 0.6 0.6 0.9 1.8 65.6 2.0 3.1 1.6 3.7 1.0 0.0 1.1 0.6 0.3 1.6 0.2 28.1 0.5 0.3 2.2 0.8 1.7 1.2 1.9 0.1 0.6 16.8 4.0 3.5 0.9 6.5 0.2 2.8 3.6 0.2 0.2 0.3 0.0 0.4 0.1 2.0 1.2 0.6 0.3 11.5 0.7 3.6 3.0 3.3 5.3 2.3 8.0 1.2 3.5 1.5 19.2 116.4 2.5 3.7 8.2 0.5 4.5 3.0 0.2 0.5 3.2 1.3 2.4 2.9 4.0 2.4 0.3 2.1 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.7 45.2 36.7 34.2 20.0 27.6 41.2 43.1 37.7 29.0 48.4 65.6 2.1 0.0 0.0 2.3 3.6 2.2 0.9 0.1 3.4 23.4 7.4 6.1 8.1 1.5 0.8 1.8 33.3 0.3 10.4 1.2 7.9 1.7 29.1 1.2 0.5 1.3 7.7 0.0 1.3 0.8 0.2 1.5 1.5 1.8 0.0 0.7 0.7 1.3 0.3 77.4 6.7 5.8 0.0 0.0 2.1 13.4 1.2 1.9 7.2 0.0 0.1 11.2 0.0 9.5 78.5 1.1 0.2 0.4 1.3 1.7 0.9 0.7 0.6 50.3 0.0 2.6 1.5 1.1 5.7 3.3 1.8 0.8 3.7 6.0 1.6 0.4 FANCD2 "FA-D2, FACD, FAD, FANCD" ENSG00000144554 "FA complementation group D2" Q9BXW9 3 10026414-10101932 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" "Cancer-related genes, Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 17.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 25.2;Spermatocytes: 62.5;Spermatogonia: 30.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 120.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB016117, HPA063742" Approved Supported "Nucleoplasm,Nucleoli,Nuclear bodies,Cytosol" No No "Cluster 46: Basophils - DNA binding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 28: BEWO - Transcription regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nucleoli, Nuclear bodies, Cytosol" "CAB016117: AB_2278211, HPA063742: AB_2685110" "unprognostic (3.25e-2)" "unprognostic (1.09e-1)" "unprognostic (6.21e-2)" "unprognostic (1.12e-2)" "unprognostic (2.92e-1)" "unprognostic (3.36e-2)" "unprognostic (1.08e-5)" "unprognostic (2.96e-2)" "unprognostic (1.59e-3)" "prognostic unfavorable (5.00e-5)" "unprognostic (1.23e-2)" "unprognostic (9.14e-2)" "unprognostic (4.41e-10)" "unprognostic (9.11e-3)" "unprognostic (3.99e-1)" "unprognostic (7.76e-2)" "unprognostic (2.89e-2)" 1.1 0.7 2.7 7.7 2.1 17.8 3.4 1.6 5.3 1.5 1.1 4.0 3.2 2.0 0.7 2.5 2.6 2.0 0.5 3.4 1.6 0.9 1.1 1.9 12.2 3.9 1.4 3.6 0.8 0.8 0.5 4.7 3.0 1.9 6.4 3.1 4.9 1.0 4.8 4.5 4.0 2.0 2.4 6.4 3.5 11.8 2.3 9.8 1.9 0.4 13.0 2.3 1.3 5.1 24.1 25.4 46.5 13.2 2.4 3.5 120.7 22.0 9.8 31.3 25.4 18.8 23.0 46.7 9.8 7.0 25.1 20.2 48.8 16.7 31.0 22.6 33.0 63.6 39.6 17.9 0.4 48.1 37.9 1.2 2.6 34.1 18.4 4.2 18.4 39.3 39.6 51.6 23.1 27.2 40.6 17.9 56.1 18.1 17.6 43.4 37.7 32.5 10.3 26.7 13.0 25.3 26.4 20.1 8.3 33.5 31.0 29.4 10.6 24.6 28.4 15.1 31.5 21.7 46.4 77.2 14.1 47.7 43.2 2.7 0.6 1.9 0.6 0.5 0.6 2.4 0.9 0.5 0.4 3.2 1.1 0.9 1.5 1.0 1.4 1.8 1.5 0.5 2.7 2.1 1.6 5.3 3.4 1.6 3.9 1.4 3.0 2.4 2.3 5.1 0.7 0.0 0.5 0.7 12.5 4.6 3.5 2.9 2.8 3.1 4.5 2.7 2.0 1.5 1.9 1.8 10.4 12.7 5.6 3.1 0.0 1.9 5.9 2.6 1.5 2.1 1.2 25.2 3.0 3.5 15.2 2.6 2.0 3.4 1.3 11.8 3.3 1.5 5.7 0.0 2.6 3.2 6.1 3.8 7.0 8.0 2.1 3.7 3.6 1.9 4.9 0.6 1.0 1.5 2.4 1.8 3.6 1.5 8.1 2.2 0.5 0.7 2.0 5.6 19.7 2.6 2.1 62.5 30.2 4.1 2.7 7.0 5.2 1.6 7.6 3.1 FANCI "FLJ10719, KIAA1794" ENSG00000140525 "FA complementation group I" Q9NVI1 15 89243945-89317261 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, DNA damage, DNA repair" DNA-binding "Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 31.4;lymphoid tissue: 44.2;testis: 32.6" "Cell type enhanced" "Detected in many" "Erythroid cells: 48.6;Spermatocytes: 69.5;Spermatogonia: 60.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "basophil: 23.4" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA039972, HPA040379" Approved Enhanced Nucleoplasm NA NA "Cluster 38: Basophils - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA039972: AB_10673265, HPA040379: AB_2676951" "unprognostic (6.88e-2)" "unprognostic (1.37e-2)" "unprognostic (1.66e-1)" "unprognostic (2.50e-2)" "unprognostic (2.99e-1)" "unprognostic (2.64e-2)" "prognostic unfavorable (1.11e-4)" "unprognostic (6.82e-3)" "unprognostic (1.15e-2)" "unprognostic (4.59e-3)" "prognostic unfavorable (3.59e-4)" "unprognostic (1.04e-1)" "prognostic unfavorable (2.71e-13)" "unprognostic (2.40e-2)" "unprognostic (2.72e-1)" "unprognostic (1.27e-1)" "unprognostic (2.12e-1)" 3.2 2.1 1.6 13.0 1.3 31.4 6.0 3.8 2.5 3.3 0.0 10.5 6.0 4.7 1.1 8.1 3.4 3.0 1.7 1.7 0.7 1.7 2.9 3.4 23.9 1.2 0.9 3.8 3.0 3.0 0.6 11.3 1.7 3.6 12.4 5.4 2.8 2.0 0.8 8.0 7.3 6.9 0.6 6.0 6.7 32.6 1.3 44.2 2.0 0.8 26.6 5.4 3.7 1.7 108.2 122.4 127.8 86.1 10.8 16.0 78.5 101.4 58.3 123.6 150.5 96.8 95.4 198.8 53.4 33.8 79.3 143.9 196.8 69.0 116.2 127.8 123.5 197.2 176.7 45.8 1.7 146.0 96.3 8.6 6.8 87.1 44.4 17.6 51.7 120.2 139.2 142.3 83.5 61.5 150.9 49.6 101.1 70.3 44.5 130.6 187.1 84.6 28.5 196.8 93.9 80.8 105.2 73.3 46.7 85.7 81.2 64.8 35.4 103.2 103.8 94.9 155.8 93.3 209.5 151.9 38.5 125.7 104.7 23.4 2.3 3.0 4.7 3.0 2.8 3.5 4.7 6.5 2.2 3.6 3.3 5.6 3.1 5.1 4.3 4.1 11.8 3.1 1.6 1.3 3.8 2.5 1.7 0.7 1.2 0.9 1.7 0.6 1.3 1.7 2.6 3.2 1.5 3.6 3.8 4.2 2.6 4.0 0.6 2.4 2.9 2.7 3.9 0.0 3.3 1.8 0.0 17.0 3.9 4.2 0.0 2.0 7.9 5.0 3.7 3.0 1.2 48.6 7.0 2.9 18.3 3.9 5.6 4.5 2.5 14.9 6.8 0.8 8.1 1.7 5.8 5.9 0.0 3.0 3.8 7.9 3.4 4.8 1.8 1.9 3.3 11.6 1.0 9.0 6.9 2.5 1.2 1.5 13.9 2.0 1.3 1.0 6.3 1.9 6.6 3.6 4.0 69.5 60.2 9.2 2.4 12.4 8.1 2.5 9.1 2.8 FCGR1A "CD64, CD64A" ENSG00000150337 "Fc fragment of IgG receptor Ia" P12314 1 149782671-149791675 "CD markers, FDA approved drug targets, Predicted membrane proteins" "Immunity, Innate immunity" "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 93.3;lymphoid tissue: 41.3" "Cell type enhanced" "Detected in some" "Hofbauer cells: 283.3;Kupffer cells: 140.9;Late spermatids: 64.9;Macrophages: 94.9" "Cancer enriched" "Detected in many" 4 "glioma: 10.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "classical monocyte: 131.5;intermediate monocyte: 54.7;myeloid DC: 35.6;neutrophil: 93.4" "Group enriched" "Detected in many" 53 "dendritic cells: 35.6;granulocytes: 93.4;monocytes: 131.5" "Cell line enriched" "Detected in some" 5 "THP-1: 191.6" "Low region specificity" "Detected in all" HPA026910 Uncertain "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "Golgi apparatus, Plasma membrane" "HPA026910: " "unprognostic (5.27e-2)" "unprognostic (2.89e-2)" "unprognostic (2.34e-2)" "unprognostic (7.97e-2)" "unprognostic (8.44e-3)" "unprognostic (1.73e-1)" "unprognostic (7.69e-2)" "unprognostic (1.04e-1)" "unprognostic (1.88e-2)" "unprognostic (1.72e-1)" "unprognostic (1.98e-2)" "unprognostic (6.18e-2)" "prognostic unfavorable (4.83e-8)" "unprognostic (1.28e-1)" "unprognostic (4.51e-2)" "unprognostic (9.99e-2)" "unprognostic (9.03e-2)" 12.2 7.2 8.4 41.3 8.9 17.9 3.6 8.8 12.8 4.2 8.4 2.3 1.1 1.6 93.3 1.7 1.8 8.2 2.2 8.6 9.4 2.8 4.2 28.6 14.4 14.6 10.6 2.3 4.3 2.7 2.5 32.6 13.0 1.6 2.1 2.3 1.9 2.4 0.3 0.4 1.3 19.1 13.2 12.5 2.1 3.7 12.2 1.4 1.4 0.8 0.8 14.7 0.8 18.9 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 13.3 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 41.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 1.0 0.0 0.0 0.1 0.3 191.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 24.4 0.0 2.0 131.5 1.6 0.0 54.7 0.7 1.6 0.0 0.3 35.6 0.0 0.0 0.1 93.4 0.0 11.8 0.9 0.3 48.5 8.4 8.9 8.8 12.8 8.6 9.4 14.6 10.6 13.0 13.2 12.2 18.9 0.3 0.0 3.1 0.0 0.8 0.1 0.0 0.0 0.6 1.5 0.2 0.8 1.7 1.5 1.3 0.0 2.1 2.7 0.0 0.0 0.0 0.0 30.8 0.1 0.1 9.3 0.0 2.7 0.1 0.0 1.3 1.0 0.0 0.1 0.0 0.2 1.8 0.5 283.3 0.0 0.1 0.0 0.0 140.9 6.0 64.9 0.3 94.9 0.0 7.5 34.7 0.3 0.0 0.5 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.2 0.7 1.3 6.6 0.2 0.3 0.6 0.4 0.1 0.0 4.1 0.6 0.1 0.1 0.0 FER1L6 C8ORFK23 ENSG00000214814 "Fer-1 like family member 6" Q2WGJ9 8 123851987-124120061 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "intestine: 10.8;stomach 1: 43.1" "Group enriched" "Detected in some" 9 "Early spermatids: 15.8;Gastric mucus-secreting cells: 39.3;Intestinal goblet cells: 10.4;Late spermatids: 30.5;Pancreatic endocrine cells: 10.8" "Group enriched" "Detected in some" 6 "pancreatic cancer: 4.2;stomach cancer: 5.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 1.0;ASC TERT1: 1.8;BJ hTERT+: 1.2;PC-3: 1.7;U-87 MG: 1.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA054117 Enhanced NA NA "Cluster 4: Stomach - Digestion" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA054117: AB_2682387" "unprognostic (1.90e-1)" "unprognostic (3.08e-3)" "unprognostic (2.06e-3)" "unprognostic (3.91e-2)" "unprognostic (2.09e-1)" "unprognostic (9.49e-3)" "unprognostic (1.36e-1)" "unprognostic (3.83e-1)" "unprognostic (2.66e-2)" "unprognostic (2.17e-1)" "unprognostic (1.55e-2)" "unprognostic (3.32e-2)" "unprognostic (3.23e-6)" "unprognostic (7.09e-2)" "unprognostic (8.43e-2)" "unprognostic (2.79e-3)" "unprognostic (6.39e-2)" 0.0 0.0 0.3 0.3 0.2 0.0 0.0 0.0 0.2 0.3 0.0 5.0 2.9 0.0 0.0 0.1 0.2 0.0 0.1 0.4 0.0 3.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.8 0.0 0.0 0.0 0.1 0.0 4.5 0.1 0.0 0.0 43.1 2.5 0.0 0.0 2.2 0.0 0.0 0.1 0.0 0.0 0.0 0.2 1.0 0.0 0.0 1.8 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.5 1.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.2 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.7 0.0 1.8 0.0 0.0 0.0 0.0 0.6 0.0 0.4 15.8 0.3 0.0 0.0 0.0 0.0 1.6 0.4 0.0 0.0 39.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 10.4 0.0 0.0 0.0 30.5 0.9 0.0 0.0 1.9 0.0 0.0 0.0 1.0 1.0 10.8 2.2 0.0 0.1 0.0 0.1 0.6 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.2 0.1 0.8 FFAR2 "FFA2R, GPR43" ENSG00000126262 "Free fatty acid receptor 2" O15552 19 35443907-35451767 "G-protein coupled receptors, Predicted membrane proteins" "Immunity, Inflammatory response" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 20.3;lymphoid tissue: 22.2" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 24.1;Intestinal goblet cells: 8.9;Kupffer cells: 11.9;Macrophages: 15.4;Prostatic glandular cells: 7.7" "Cancer enhanced" "Detected in many" "prostate cancer: 6.0" "Not detected" "Not detected" "Group enriched" "Detected in many" 25 "eosinophil: 85.0;neutrophil: 249.7" "Lineage enriched" "Detected in many" 38 "granulocytes: 249.7" "Cell line enhanced" "Detected in some" "HMC-1: 3.9;OE19: 1.8;SK-BR-3: 1.1;THP-1: 1.2;U-937: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA023985 Approved NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA023985: AB_1849302" "unprognostic (7.75e-3)" "unprognostic (5.65e-2)" "unprognostic (4.33e-3)" "unprognostic (1.68e-1)" "unprognostic (2.18e-1)" "unprognostic (2.55e-2)" "unprognostic (6.16e-2)" "unprognostic (2.04e-1)" "unprognostic (1.92e-2)" "unprognostic (9.04e-2)" "unprognostic (2.30e-2)" "unprognostic (4.60e-2)" "unprognostic (5.17e-4)" "unprognostic (1.48e-1)" "unprognostic (4.76e-2)" "unprognostic (9.42e-2)" "unprognostic (1.03e-2)" 4.9 0.3 0.2 17.8 0.4 20.3 2.3 0.2 0.4 0.2 0.6 0.8 3.3 0.1 0.0 1.3 1.0 1.4 1.0 0.2 0.2 0.3 1.5 7.5 0.1 0.4 0.4 0.0 0.6 0.3 0.1 1.6 0.5 1.1 0.7 0.1 0.7 0.0 0.2 1.1 4.6 1.3 0.2 22.2 1.2 0.0 0.4 0.7 0.4 3.7 0.7 6.0 0.7 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 3.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.8 0.0 0.6 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 1.1 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 3.1 2.1 85.0 0.0 5.6 0.0 0.1 0.0 0.0 0.9 0.2 0.0 0.0 249.7 0.0 6.5 0.1 0.0 0.7 0.2 0.4 0.2 0.4 0.2 0.2 0.4 0.4 0.5 0.2 0.4 0.8 5.6 0.0 3.2 0.0 0.6 0.1 0.4 0.3 0.0 0.0 0.2 0.3 0.4 0.0 2.7 0.0 0.0 0.0 0.3 0.3 0.0 0.3 0.2 0.0 0.1 0.8 24.1 0.0 0.0 0.0 0.1 1.4 0.0 0.0 5.1 0.0 0.4 0.0 5.0 0.0 0.0 8.9 2.0 11.9 2.6 0.1 0.0 15.4 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 7.7 1.1 0.0 2.2 0.0 0.0 0.4 2.4 0.1 0.2 0.0 0.6 0.1 1.3 0.1 0.6 1.5 FGD2 ZFYVE4 ENSG00000146192 "FYVE, RhoGEF and PH domain containing 2" Q7Z6J4 6 37005646-37029069 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 39.7" "Cell type enhanced" "Detected in many" "B-cells: 53.7;dendritic cells: 29.7;Kupffer cells: 118.2;Langerhans cells: 49.3;Macrophages: 52.0;Microglial cells: 43.1;monocytes: 51.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "classical monocyte: 22.3;intermediate monocyte: 64.8;memory B-cell: 23.2;myeloid DC: 35.0;naive B-cell: 18.6;non-classical monocyte: 70.5;plasmacytoid DC: 27.4" "Group enriched" "Detected in many" 18 "B-cells: 23.2;dendritic cells: 35.0;monocytes: 70.5" "Cell line enhanced" "Detected in some" "CAPAN-2: 2.7;Daudi: 11.5;HDLM-2: 11.3;U-698: 9.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA029145, HPA049692" Approved NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA029145: AB_10601321, HPA049692: AB_2680852" "unprognostic (3.54e-2)" "unprognostic (1.40e-4)" "unprognostic (5.69e-3)" "unprognostic (2.29e-1)" "unprognostic (1.27e-1)" "unprognostic (1.67e-4)" "unprognostic (7.97e-2)" "unprognostic (1.58e-2)" "unprognostic (2.47e-2)" "unprognostic (2.78e-1)" "unprognostic (3.39e-2)" "unprognostic (2.82e-1)" "unprognostic (1.15e-2)" "unprognostic (3.91e-1)" "unprognostic (1.02e-2)" "unprognostic (3.88e-1)" "unprognostic (7.10e-2)" 6.1 3.3 1.0 14.8 1.3 6.0 2.6 1.2 1.3 1.5 2.3 3.4 3.7 1.3 1.5 2.4 2.8 4.1 1.6 1.0 1.6 1.4 2.5 8.0 22.5 3.2 1.7 1.0 1.3 0.3 1.1 2.7 1.9 1.5 2.7 0.1 2.3 1.8 0.6 2.1 11.1 4.7 2.1 39.7 3.8 0.6 2.1 5.5 2.7 0.9 9.8 4.5 1.6 2.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 11.5 0.0 0.0 0.0 0.4 0.0 0.0 0.3 11.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.0 1.7 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.3 0.0 0.0 0.0 0.1 22.3 2.3 0.1 64.8 0.1 23.2 0.0 0.0 35.0 18.6 0.0 0.0 0.3 0.4 70.5 27.4 0.1 7.5 1.0 1.3 1.2 1.3 1.0 1.6 3.2 1.7 1.9 2.1 2.1 2.0 0.3 6.4 7.4 0.0 53.7 2.0 3.0 1.0 0.6 0.3 0.7 0.6 3.2 2.8 0.5 0.0 0.0 0.3 29.7 0.3 0.0 2.8 11.9 0.5 0.2 1.2 0.0 1.3 0.1 0.9 0.4 1.0 1.5 1.2 7.6 0.0 2.5 0.6 17.7 0.0 0.2 0.1 4.1 118.2 49.3 2.1 1.5 52.0 1.8 43.1 51.8 0.4 2.1 0.5 0.2 1.0 3.9 0.0 14.2 1.6 0.1 0.2 3.2 0.2 0.0 2.3 0.5 0.0 0.1 3.3 2.3 0.4 3.0 0.1 0.4 5.6 FLT3 "CD135, FLK2, STK1" ENSG00000122025 "Fms related receptor tyrosine kinase 3" P36888 13 28003274-28100592 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, RAS pathway related proteins" "Host-virus interaction" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.3;brain: 4.9;lymphoid tissue: 6.5" "Cell type enhanced" "Detected in some" "dendritic cells: 24.4;Inhibitory neurons: 59.9;Kupffer cells: 29.1;Langerhans cells: 21.4;Macrophages: 16.9;monocytes: 39.5" "Cancer enhanced" "Detected in some" "breast cancer: 1.8" "Region enhanced" "Detected in some" "cerebellum: 4.9" "Group enriched" "Detected in many" 13 "myeloid DC: 68.7;plasmacytoid DC: 26.2" "Lineage enriched" "Detected in many" 19 "dendritic cells: 68.7" "Group enriched" "Detected in some" 11 "REH: 42.5;THP-1: 26.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA047539 Approved "Endoplasmic reticulum" NA NA 210000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 14: REH - Unknown function" "Cluster 41: Macrophages - Immune response" "Endoplasmic reticulum" "HPA047539: AB_2680080" "unprognostic (2.19e-3)" "unprognostic (3.16e-3)" "unprognostic (6.54e-3)" "unprognostic (9.96e-2)" "unprognostic (3.88e-1)" "unprognostic (3.96e-7)" "unprognostic (7.99e-3)" "unprognostic (1.65e-2)" "unprognostic (5.37e-2)" "unprognostic (1.01e-2)" "unprognostic (1.96e-1)" "unprognostic (1.03e-1)" "unprognostic (4.56e-2)" "unprognostic (3.65e-1)" "unprognostic (3.91e-2)" "unprognostic (2.51e-1)" "unprognostic (2.22e-1)" 0.5 0.1 0.3 3.0 0.2 5.3 1.5 4.9 0.8 0.5 0.1 0.7 0.3 0.2 0.1 0.6 0.4 1.6 0.1 0.2 0.5 1.5 0.5 0.7 6.5 1.3 0.9 0.1 2.8 0.0 0.0 0.0 1.7 0.1 0.8 0.0 0.4 0.2 0.0 0.7 1.6 0.8 0.8 5.7 0.6 0.6 0.8 4.7 0.1 0.3 3.6 1.3 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 3.2 0.6 0.0 0.0 42.5 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 26.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 3.6 3.4 0.0 0.8 0.0 0.2 0.0 0.0 68.7 0.0 0.0 0.0 0.1 2.0 0.0 26.2 0.0 2.7 0.3 0.2 4.9 0.8 0.2 0.5 1.3 0.9 1.7 0.8 0.8 0.8 0.0 0.0 0.0 2.3 1.5 0.3 0.0 0.0 0.0 0.0 1.5 1.0 0.4 1.5 0.0 0.0 0.0 0.0 24.4 0.0 0.0 2.7 3.7 0.3 0.1 0.2 0.0 8.2 7.4 0.0 0.0 0.2 0.0 1.1 0.0 0.0 0.7 0.1 0.5 0.0 59.9 0.0 0.0 29.1 21.4 2.3 0.0 16.9 1.8 1.9 39.5 0.0 0.0 1.5 4.2 0.1 0.0 0.0 2.2 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.2 0.6 0.0 0.6 0.0 1.7 0.0 0.0 0.0 FOXM1 "FKHL16, HFH-11, HNF-3, INS-1, MPHOSPH2, MPP2, TGT3, trident" ENSG00000111206 "Forkhead box M1" Q08050 12 2857680-2877174 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Cell cycle, DNA damage, DNA repair, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 25.0;lymphoid tissue: 32.2;testis: 21.4" "Cell type enhanced" "Detected in many" "Early spermatids: 22.4;Erythroid cells: 18.7;Extravillous trophoblasts: 18.2;Late spermatids: 25.5;Plasma cells: 19.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" CAB017832 Uncertain Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Cytosol" NA Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nucleoli, Nucleoli rim" Cytosol "CAB017832: " "unprognostic (3.18e-2)" "unprognostic (1.69e-1)" "unprognostic (1.22e-2)" "unprognostic (1.09e-2)" "unprognostic (4.30e-2)" "unprognostic (3.75e-2)" "prognostic unfavorable (1.95e-6)" "prognostic unfavorable (2.92e-4)" "unprognostic (1.01e-2)" "unprognostic (3.25e-2)" "prognostic unfavorable (3.03e-5)" "unprognostic (6.09e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.80e-2)" "unprognostic (1.87e-1)" "unprognostic (1.29e-1)" "unprognostic (1.94e-1)" 1.9 1.1 0.4 9.4 0.5 25.0 1.8 0.8 0.8 1.7 0.2 10.5 9.7 1.7 0.2 11.1 0.8 1.5 0.5 0.8 0.3 0.7 1.2 1.8 11.3 0.4 0.9 0.3 0.4 0.4 0.1 6.1 0.6 0.7 12.5 1.1 1.9 0.8 0.6 6.4 8.8 7.5 0.1 3.1 5.2 21.4 1.0 32.2 0.9 0.3 15.2 3.0 3.2 0.6 133.0 129.5 101.3 92.2 14.2 19.0 129.2 84.0 80.4 165.2 147.2 166.9 114.8 84.5 17.7 119.8 188.5 100.2 153.1 76.1 160.0 159.8 80.3 94.7 121.6 71.6 2.0 79.2 75.0 9.9 8.3 154.4 106.1 39.1 117.8 96.8 55.6 184.9 130.5 122.6 108.3 36.8 225.6 136.1 95.4 77.3 149.8 44.1 38.1 82.7 56.3 89.1 106.7 90.4 46.6 189.4 87.1 87.8 48.0 134.3 200.5 160.4 300.4 24.7 44.3 122.1 63.1 74.3 147.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.4 0.5 0.8 0.8 0.8 0.3 0.4 0.9 0.6 0.1 1.0 0.6 0.1 0.0 1.3 0.7 2.4 2.9 1.3 1.0 1.2 2.0 1.7 1.3 0.5 1.5 0.8 1.8 4.2 7.1 0.8 6.6 1.9 0.2 22.4 1.2 2.1 2.5 0.0 18.7 1.1 0.0 18.2 3.2 10.2 2.4 0.0 15.4 3.6 0.8 9.1 5.0 0.6 7.5 2.0 4.2 1.2 25.5 0.9 2.4 0.0 0.0 1.1 0.6 1.0 0.5 1.0 0.3 0.3 0.7 19.9 1.0 1.4 0.4 0.2 4.0 0.0 1.2 3.0 15.0 9.9 10.2 1.4 1.9 3.3 0.9 12.9 1.9 FPR3 "FMLPY, FPRH1, FPRL2, RMLP-R-I" ENSG00000187474 "Formyl peptide receptor 3" P25089 19 51795157-51826190 "G-protein coupled receptors, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 28.2" "Group enriched" "Detected in some" 15 "Hofbauer cells: 56.5;Kupffer cells: 97.4;Langerhans cells: 223.6;Macrophages: 66.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 20 "classical monocyte: 2.3;intermediate monocyte: 6.7;myeloid DC: 2.4" "Group enriched" "Detected in many" 44 "dendritic cells: 2.4;monocytes: 6.7" "Group enriched" "Detected in some" 5 "HEL: 10.0;hTERT-RPE1: 2.7" "Not detected" "Not detected" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 36: HEL - Hemostasis" "Cluster 4: Macrophages - Innate immune response" "unprognostic (3.77e-2)" "unprognostic (1.54e-1)" "unprognostic (1.79e-2)" "unprognostic (1.29e-1)" "unprognostic (1.15e-1)" "unprognostic (1.84e-1)" "unprognostic (8.41e-2)" "unprognostic (1.39e-1)" "unprognostic (1.37e-2)" "unprognostic (7.14e-2)" "unprognostic (3.17e-1)" "unprognostic (9.37e-2)" "unprognostic (1.02e-3)" "unprognostic (1.59e-1)" "prognostic unfavorable (9.13e-4)" "unprognostic (1.96e-1)" "unprognostic (4.28e-2)" 10.6 12.1 0.6 23.9 1.1 0.4 5.3 0.5 2.4 5.5 2.2 12.6 11.2 3.7 1.5 5.7 2.0 18.8 3.8 0.6 0.7 3.2 21.3 28.2 13.9 3.1 1.0 1.7 2.3 2.2 0.9 5.6 2.8 2.5 18.2 0.3 2.4 2.9 0.9 2.7 14.4 8.9 1.2 16.3 7.1 2.7 6.0 8.1 2.2 2.0 11.0 17.4 1.2 3.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.3 0.0 0.0 6.7 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.5 0.6 1.1 0.5 2.4 0.6 0.7 3.1 1.0 2.8 1.2 6.0 3.9 0.5 0.0 1.7 0.3 2.7 5.6 0.0 0.0 0.0 0.1 0.1 0.5 0.2 0.0 2.5 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.3 0.0 0.4 0.8 0.0 0.0 0.0 0.0 1.1 1.5 56.5 0.0 0.2 0.0 0.0 97.4 223.6 0.2 0.3 66.6 7.2 1.0 3.7 0.0 0.0 0.0 0.7 0.0 0.0 1.2 0.4 0.1 0.0 0.0 1.5 0.1 0.0 0.3 0.5 0.0 0.1 0.4 4.5 0.8 0.6 0.0 0.0 0.1 FRMD1 "bA164L23.1, DKFZp434O0117, FLJ00181, FLJ22615, FLJ40260" ENSG00000153303 "FERM domain containing 1" Q8N878 6 168053166-168101511 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 6.8;lymphoid tissue: 13.1;stomach 1: 5.7;testis: 5.1" "Group enriched" "Detected in some" 4 "Distal enterocytes: 68.9;Paneth cells: 167.2" "Cancer enriched" "Detected in single" 6 "colorectal cancer: 1.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "K-562: 1.9;RPMI-8226: 3.0" "Low region specificity" "Detected in many" HPA030347 Enhanced Approved "Actin filaments" NA NA "Cluster 3: T-cells - Adaptive immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Actin filaments" "HPA030347: AB_10600207" "unprognostic (2.43e-2)" "unprognostic (2.74e-1)" "unprognostic (2.50e-1)" "unprognostic (1.28e-1)" "unprognostic (1.25e-1)" "unprognostic (2.58e-4)" "unprognostic (8.63e-2)" "unprognostic (2.62e-1)" "unprognostic (7.51e-2)" "unprognostic (9.12e-2)" "unprognostic (8.23e-2)" "unprognostic (1.71e-2)" "unprognostic (1.01e-1)" "unprognostic (9.11e-3)" 3.6 0.0 0.0 0.4 0.0 0.0 1.4 0.0 0.0 0.0 0.0 6.8 1.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.6 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.1 0.0 0.2 0.0 3.1 0.1 0.0 2.1 5.7 5.1 0.0 13.1 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.5 0.0 0.0 1.8 0.0 0.0 0.0 68.9 0.0 0.0 15.3 0.0 0.0 0.2 7.8 0.0 0.0 1.8 0.0 0.4 4.6 0.1 0.0 0.3 0.4 0.6 0.0 0.0 0.0 16.0 0.0 0.0 0.0 20.2 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 167.2 1.5 0.0 0.0 19.6 23.8 0.0 0.0 0.0 0.3 0.7 13.4 8.2 0.0 0.0 0.1 0.1 15.2 12.6 0.2 FSIP2 FLJ34780 ENSG00000188738 "Fibrous sheath interacting protein 2" Q5CZC0 2 185738804-185833290 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "testis: 18.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 137.8;Alveolar cells type 2: 93.8;Early spermatids: 289.6;Gastric mucus-secreting cells: 68.3;Spermatocytes: 124.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "RT4: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA036139 Approved Microtubules,Mitochondria NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 15: RT4 - Unknown function" "Cluster 23: Spermatids - Flagellum & Golgi organization" Microtubules Mitochondria "HPA036139: AB_10602134" "unprognostic (5.28e-2)" "unprognostic (1.20e-2)" "unprognostic (4.17e-1)" "unprognostic (5.81e-2)" "unprognostic (1.67e-1)" "unprognostic (2.95e-1)" "unprognostic (6.31e-2)" "unprognostic (2.76e-3)" "unprognostic (1.55e-1)" "unprognostic (5.24e-2)" "unprognostic (4.37e-3)" "unprognostic (2.79e-3)" "unprognostic (4.89e-3)" "unprognostic (1.28e-1)" "unprognostic (7.52e-2)" "unprognostic (5.17e-2)" "unprognostic (4.64e-5)" 0.1 0.2 0.3 0.2 0.5 0.0 0.2 0.3 0.3 0.2 0.0 1.5 0.0 0.2 0.2 0.0 0.1 0.1 0.1 0.2 0.3 0.1 0.0 0.0 0.0 0.5 0.4 0.2 0.2 0.2 0.4 0.1 0.6 0.2 0.9 0.6 0.2 0.0 0.0 0.2 0.2 0.0 0.6 0.0 2.6 18.3 0.3 0.1 0.2 0.0 0.0 0.2 0.1 0.9 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.2 0.6 0.2 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.3 0.3 0.2 0.3 0.5 0.4 0.6 0.6 0.3 0.9 1.7 137.8 93.8 5.2 2.6 0.5 0.1 1.4 1.8 16.3 3.0 1.7 3.9 0.0 31.5 0.0 10.4 0.3 1.0 26.0 0.0 0.7 289.6 3.3 3.3 5.6 7.7 0.0 4.5 0.2 0.1 7.3 68.3 2.1 40.4 2.7 1.8 0.1 0.4 18.5 5.4 19.7 0.0 0.8 1.0 50.8 2.1 5.9 1.8 3.7 0.7 3.9 2.1 23.6 14.0 5.4 5.5 3.8 1.3 0.2 0.5 0.2 46.0 7.2 0.0 4.0 0.8 124.4 5.4 0.2 0.3 0.3 6.0 2.6 5.2 0.2 FUT3 "CD174, LE" ENSG00000171124 "Fucosyltransferase 3 (Lewis blood group)" P21217 19 5842888-5851474 "Blood group antigen proteins, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Blood group antigen, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 158.7;intestine: 72.3;retina: 79.3;salivary gland: 84.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 154.7;Intestinal goblet cells: 78.7;Pancreatic endocrine cells: 49.0;Paneth cells: 88.9;Proximal enterocytes: 85.2;Undifferentiated cells: 65.6" "Cancer enhanced" "Detected in many" "colorectal cancer: 41.4" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 46.3;hTCEpi: 6.9;OE19: 20.6;RH-30: 14.8;SK-BR-3: 7.1" HPA046966 Supported NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA046966: AB_2679879" "prognostic unfavorable (6.86e-4)" "unprognostic (2.59e-1)" "unprognostic (1.06e-1)" "unprognostic (9.12e-2)" "unprognostic (8.58e-3)" "unprognostic (1.63e-3)" "unprognostic (3.88e-2)" "unprognostic (2.03e-2)" "unprognostic (4.02e-2)" "unprognostic (3.98e-2)" "unprognostic (4.21e-2)" "unprognostic (2.99e-1)" "prognostic favorable (8.22e-7)" "unprognostic (5.66e-3)" "unprognostic (9.56e-2)" "unprognostic (4.30e-2)" "unprognostic (1.07e-1)" 0.5 0.0 0.4 12.6 0.6 0.7 1.2 0.5 0.7 25.9 0.5 72.3 47.7 0.3 0.0 158.7 1.3 22.4 0.2 0.4 1.2 9.8 2.3 5.2 0.1 0.8 0.5 0.1 9.1 0.0 0.6 0.1 0.7 2.2 44.5 79.3 84.2 8.5 0.1 3.2 56.3 2.8 0.2 0.2 20.8 4.0 0.6 0.2 0.0 0.0 15.9 3.0 53.2 0.7 46.3 0.0 0.2 0.2 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.1 5.2 0.0 0.6 0.0 0.0 2.0 0.0 0.4 0.0 0.2 0.2 0.0 0.0 0.3 0.0 0.0 0.1 0.0 6.9 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.1 20.6 0.0 0.0 14.8 1.6 0.0 0.6 0.0 0.2 0.0 7.1 0.2 0.1 0.1 0.4 0.0 0.2 0.1 0.1 0.3 0.3 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.6 0.5 0.7 0.4 1.2 0.8 0.5 0.7 0.2 0.6 0.7 0.1 0.0 4.8 0.3 1.1 0.0 3.0 23.6 0.0 1.8 1.7 0.3 0.3 11.5 36.4 0.0 0.0 0.1 0.0 154.7 0.0 43.2 4.9 1.1 0.1 0.5 13.8 0.0 0.1 14.2 0.4 0.0 18.3 0.6 8.9 0.1 0.0 0.4 0.0 0.0 0.0 78.7 14.2 0.0 0.0 8.7 0.0 0.2 0.0 1.0 0.0 1.9 0.0 0.0 0.1 49.0 88.9 0.0 0.1 0.9 85.2 16.5 22.8 34.9 0.0 0.0 1.5 0.5 0.2 6.5 0.0 0.3 0.5 0.0 65.6 27.3 GBGT1 "A3GALNT, FS, MGC44848, UDP-GalNAc" ENSG00000148288 "Globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 (FORS blood group)" Q8N5D6 9 133152948-133163933 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 16.4;Hofbauer cells: 21.3;Kupffer cells: 31.9;Macrophages: 22.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 64.1;HMC-1: 57.1;HUVEC TERT2: 24.0;NB-4: 29.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051298 Approved "Intracellular and membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "HPA051298: AB_2681428" "unprognostic (4.63e-3)" "unprognostic (8.03e-2)" "prognostic unfavorable (6.22e-4)" "unprognostic (2.70e-1)" "unprognostic (8.87e-2)" "unprognostic (4.38e-1)" "unprognostic (2.97e-2)" "unprognostic (7.43e-2)" "unprognostic (9.04e-2)" "unprognostic (2.27e-3)" "unprognostic (2.35e-1)" "unprognostic (9.50e-2)" "prognostic unfavorable (3.46e-5)" "unprognostic (2.92e-2)" "unprognostic (1.01e-1)" "unprognostic (3.41e-2)" "unprognostic (6.35e-2)" 9.9 10.5 6.3 11.0 5.9 9.9 6.5 11.8 7.0 5.4 11.8 5.3 3.3 6.7 2.7 3.6 7.4 7.5 6.7 5.9 8.2 5.6 1.3 9.7 9.7 13.5 11.2 12.5 3.4 4.8 4.2 12.8 13.8 6.1 3.2 1.0 4.8 4.2 2.2 3.5 6.7 6.7 7.7 8.9 22.2 1.3 11.5 2.7 6.7 2.9 8.1 6.0 6.3 8.5 0.1 1.6 1.5 0.0 1.0 1.1 0.5 4.7 3.8 2.6 0.1 0.0 0.9 1.2 15.5 4.7 1.7 17.3 10.5 1.0 0.1 0.0 0.5 64.1 1.1 0.0 12.4 2.4 57.1 5.3 1.7 0.6 0.1 10.5 24.0 0.8 18.7 0.2 1.0 0.3 0.2 29.0 4.9 0.5 0.4 4.5 0.4 1.7 1.6 0.2 0.4 1.8 0.0 2.6 0.1 2.0 0.1 14.0 14.8 0.0 2.0 1.9 0.1 0.0 0.0 0.1 0.3 10.2 0.8 6.2 10.7 5.2 0.2 7.2 0.4 1.8 0.3 0.0 3.0 2.7 0.1 0.1 1.7 0.2 6.4 2.2 0.2 2.5 6.3 5.9 11.8 7.0 5.9 8.2 13.5 11.2 13.8 7.7 11.5 8.5 1.6 0.0 1.7 4.9 4.9 0.8 2.2 0.6 2.8 0.3 4.1 2.7 2.6 1.5 0.7 1.8 0.0 2.4 0.0 0.6 0.0 3.2 0.0 0.5 1.8 1.8 0.0 16.4 2.4 0.6 1.1 7.3 2.6 0.3 11.4 3.6 0.7 0.0 21.3 0.0 1.9 0.3 0.0 31.9 3.1 0.0 7.5 22.0 0.0 5.6 11.1 2.4 0.0 1.5 0.0 0.8 12.1 1.9 0.7 1.5 0.1 1.6 0.0 0.2 0.0 3.9 6.2 0.1 0.1 1.4 1.1 3.6 2.0 0.5 1.2 1.7 GCKR ENSG00000084734 "Glucokinase regulator" 2 27496839-27523684 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "liver: 136.4" "Cell type enriched" "Detected in some" 5 "Hepatocytes: 96.5" "Cancer enriched" "Detected in some" 8 "liver cancer: 14.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 13.4;Hep G2: 20.7;HUVEC TERT2: 6.4;TIME: 4.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB034098, HPA045855, HPA052227" Enhanced Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 11: Basophils - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Nucleoplasm, Cytosol" Nucleoli "CAB034098: AB_2247323, HPA045855: , HPA052227: " "unprognostic (3.31e-1)" "unprognostic (2.11e-3)" "unprognostic (2.27e-1)" "unprognostic (6.97e-2)" "unprognostic (1.68e-2)" "unprognostic (5.70e-2)" "unprognostic (2.31e-1)" "unprognostic (1.70e-1)" "unprognostic (1.52e-1)" "unprognostic (4.12e-1)" "unprognostic (2.25e-3)" "unprognostic (1.65e-1)" "unprognostic (1.02e-7)" "unprognostic (6.51e-2)" "unprognostic (1.18e-1)" "unprognostic (9.27e-3)" "unprognostic (1.50e-2)" 0.8 7.1 0.8 0.2 1.3 0.9 0.6 4.7 1.6 0.5 1.4 0.1 0.7 0.5 0.6 1.5 0.2 2.3 0.4 1.0 1.3 0.5 136.4 0.2 0.6 1.7 1.2 5.8 1.8 0.2 0.4 0.2 1.6 0.5 0.3 0.9 0.4 0.2 0.3 0.8 0.2 0.3 0.3 1.6 6.5 2.7 1.1 0.2 0.1 0.1 0.3 0.3 0.4 1.4 0.2 0.4 0.4 0.2 0.3 0.2 0.1 0.0 0.1 0.3 0.0 0.4 0.1 0.2 0.5 0.7 0.2 0.2 0.2 0.0 0.0 0.1 0.0 13.4 0.7 20.7 0.8 0.0 0.4 0.3 1.0 0.5 0.1 2.2 6.4 0.1 0.0 0.2 0.2 0.0 0.1 0.7 0.1 0.0 0.0 0.3 0.0 0.1 0.2 0.2 0.0 0.1 0.1 0.2 0.1 0.1 0.5 0.2 4.2 0.1 0.3 0.6 0.2 0.4 0.1 0.2 1.2 0.1 0.2 0.8 0.2 0.0 0.1 0.2 0.1 0.1 0.0 0.1 0.0 0.4 0.1 0.1 0.4 0.3 0.0 0.1 0.0 0.2 0.8 1.3 4.7 1.6 1.0 1.3 1.7 1.2 1.6 0.3 1.1 1.4 0.3 0.0 0.0 1.0 0.4 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.3 2.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 10.1 7.9 0.1 0.6 0.6 0.0 0.0 2.0 10.4 0.0 0.2 18.3 0.1 0.0 0.1 0.7 96.5 0.1 0.0 1.6 0.0 0.0 2.1 0.0 3.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.2 13.7 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 1.7 0.2 0.4 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 GKN1 "AMP18, BRICD1, CA11" ENSG00000169605 "Gastrokine 1" Q9NS71 2 68974573-68980980 "Plasma proteins, Predicted secreted proteins" Mitogen "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 1840 "stomach 1: 37425.0" "Cell type enriched" "Detected in some" 28 "Gastric mucus-secreting cells: 9780.9" "Cancer enriched" "Detected in some" 116 "stomach cancer: 255.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 6.5;HMC-1: 17.2;MOLT-4: 12.4;NTERA-2: 16.0;REH: 7.2;U-2 OS: 10.1;U-266/70: 10.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA047684 Enhanced "Secreted to digestive system" NA NA 18000000 "Cluster 4: Stomach - Digestion" "Cluster 3: HMC-1 - Innate immune response" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA047684: AB_2680120" "unprognostic (5.40e-2)" "prognostic unfavorable (1.54e-4)" "unprognostic (4.54e-1)" "prognostic favorable (4.53e-4)" 3.0 1.8 0.0 0.1 0.0 0.0 1.3 0.0 0.1 0.4 0.0 1.4 0.0 0.3 0.0 3.6 0.4 0.0 1.0 0.0 0.0 1.8 0.8 3.5 0.0 0.0 0.0 0.4 4.8 0.0 0.3 20.3 0.0 0.7 0.3 0.0 0.4 0.1 1.0 0.5 0.4 0.0 0.0 10.4 37425.0 0.4 0.0 1.1 0.2 0.2 0.1 1.8 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.2 0.1 0.0 6.5 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 17.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 12.4 0.0 16.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.2 0.0 10.1 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.3 3.3 9780.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 346.5 0.0 0.0 26.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.6 0.5 0.0 0.0 GKN2 "blottin, BRICD1B, GDDR, PRO813, TFIZ1, VLTI465" ENSG00000183607 "Gastrokine 2" Q86XP6 2 68945232-68952893 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 57 "stomach 1: 4612.5" "Cell type enriched" "Detected in some" 22 "Gastric mucus-secreting cells: 2770.2" "Cancer enriched" "Detected in some" 8 "stomach cancer: 43.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 2.1;HaCaT: 1.1;HMC-1: 2.0;MOLT-4: 1.6;NTERA-2: 2.3;PC-3: 4.5;U-2 OS: 1.6;U-266/70: 1.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA057765 Enhanced "Secreted to digestive system" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 4: Stomach - Digestion" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA057765: AB_2683520" "unprognostic (1.81e-1)" "unprognostic (1.44e-4)" "unprognostic (2.22e-1)" 0.2 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.4 0.9 0.0 0.0 0.6 0.1 0.0 0.2 0.0 0.0 0.2 0.1 80.8 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.6 0.0 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 1.4 4612.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 2.3 0.0 4.5 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.2 0.0 1.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 115.4 109.3 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 16.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.0 0.9 2770.2 0.0 2.5 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.6 0.0 0.0 0.0 0.1 121.2 0.0 0.0 10.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.9 0.0 0.0 0.0 GPHA2 "A2, GPA2, MGC126572, ZSIG51" ENSG00000149735 "Glycoprotein hormone subunit alpha 2" Q96T91 11 64934471-64935893 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "pancreas: 360.5" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 2.5;Exocrine glandular cells: 17.4;Pancreatic endocrine cells: 2.4;Spermatocytes: 7.7;Spermatogonia: 3.2" "Cancer enriched" "Detected in some" 7 "testis cancer: 15.8" "Region enhanced" "Detected in single" "cerebellum: 3.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 11 "Hep G2: 21.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA067068 Approved Vesicles "Secreted to blood" NA NA "Cluster 25: Pancreas - Digestion" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 1: Pancreatic cells - Digestion" Vesicles "HPA067068: " "unprognostic (1.13e-1)" "unprognostic (8.31e-3)" "unprognostic (1.51e-2)" "unprognostic (9.22e-4)" "unprognostic (7.88e-3)" "unprognostic (2.62e-1)" "unprognostic (1.45e-1)" "unprognostic (3.20e-2)" "unprognostic (1.82e-1)" "unprognostic (1.75e-1)" "unprognostic (5.03e-2)" "unprognostic (9.86e-3)" "unprognostic (1.70e-1)" 0.0 0.1 0.3 0.2 0.6 0.1 0.1 3.6 0.6 0.1 0.0 0.1 0.1 0.2 0.2 0.0 0.4 16.9 0.0 0.3 0.3 0.8 0.7 0.3 0.6 0.4 0.3 2.7 360.5 0.0 28.0 0.0 0.6 0.7 0.0 0.1 0.3 0.5 0.0 0.5 0.5 0.0 0.2 0.6 1.1 10.8 0.4 0.1 0.3 0.0 0.5 0.1 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 21.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 3.6 0.6 0.3 0.3 0.4 0.3 0.6 0.2 0.4 0.9 0.0 0.0 0.0 0.0 0.0 0.3 0.1 2.5 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 17.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.4 0.0 0.5 0.2 0.0 0.0 0.0 0.0 7.7 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 GPR34 ENSG00000171659 "G protein-coupled receptor 34" Q9UPC5 X 41688973-41697275 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 42.7" "Cell type enhanced" "Detected in many" "Hofbauer cells: 251.4;Kupffer cells: 173.3;Macrophages: 100.6;Microglial cells: 54.4" "Cancer enhanced" "Detected in all" "glioma: 26.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "basophil: 339.6;eosinophil: 117.9" "Lineage enriched" "Detected in many" 24 "granulocytes: 339.6" "Cell line enhanced" "Detected in single" "HMC-1: 1.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010668, CAB025490" Uncertain Approved Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Cytosol "CAB025490: , HPA010668: AB_1849294" "unprognostic (1.26e-2)" "unprognostic (1.08e-1)" "unprognostic (1.43e-2)" "unprognostic (1.44e-2)" "unprognostic (1.20e-1)" "unprognostic (3.74e-2)" "unprognostic (5.83e-3)" "unprognostic (5.13e-2)" "unprognostic (1.59e-2)" "unprognostic (9.81e-3)" "unprognostic (7.19e-2)" "unprognostic (1.74e-1)" "unprognostic (3.96e-1)" "unprognostic (2.72e-3)" "unprognostic (1.14e-1)" "unprognostic (1.88e-3)" "unprognostic (3.18e-2)" 28.2 17.1 5.2 15.1 5.2 0.9 21.5 6.1 5.8 14.0 5.6 12.0 6.5 6.7 2.7 8.2 7.8 17.0 8.3 5.0 7.6 5.0 8.5 10.9 20.0 10.6 7.9 7.3 5.4 5.3 1.4 42.7 11.4 3.2 13.1 0.6 3.6 8.8 0.8 1.0 14.6 16.3 9.9 15.6 7.8 2.7 9.7 6.9 3.7 4.6 16.7 13.3 1.7 18.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.0 339.6 9.7 117.9 0.0 12.9 0.4 1.5 0.4 0.1 2.0 1.2 0.1 0.3 1.1 14.3 7.0 0.3 0.6 2.8 5.2 5.2 6.1 5.8 5.0 7.6 10.6 7.9 11.4 9.9 9.7 18.8 0.9 0.0 2.8 1.0 2.0 0.6 0.2 0.0 0.0 0.0 0.5 2.3 1.2 0.0 0.0 0.0 0.0 1.4 0.4 0.0 0.0 0.0 0.6 0.1 0.1 5.0 1.2 0.4 0.7 0.0 1.6 1.0 0.5 0.0 37.3 0.0 2.9 0.8 251.4 0.0 0.9 0.0 0.0 173.3 13.6 1.9 0.9 100.6 1.8 54.4 7.1 0.1 1.0 3.5 0.0 0.0 0.0 0.4 0.6 0.1 0.0 0.1 0.0 0.8 19.7 0.6 0.3 0.0 0.2 0.4 1.0 2.5 7.2 0.1 0.1 0.0 GRIP2 KIAA1719 ENSG00000144596 "Glutamate receptor interacting protein 2" Q9C0E4 3 14489107-14556075 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 13.3;skeletal muscle: 35.8;tongue: 12.5" "Cell type enriched" "Detected in many" 4 "Inhibitory neurons: 89.0" "Cancer enhanced" "Detected in single" "testis cancer: 0.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 3.1;BJ hTERT+ SV40 Large T+ RasG12V: 1.9;NTERA-2: 2.1;PC-3: 6.1;SCLC-21H: 3.4;U-2 OS: 2.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA035673 Approved Cytosol NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA035673: AB_10669776" "unprognostic (1.48e-1)" "unprognostic (6.26e-3)" "unprognostic (2.43e-2)" "unprognostic (3.13e-2)" "unprognostic (5.51e-2)" "unprognostic (1.14e-3)" "unprognostic (1.87e-1)" "unprognostic (8.19e-2)" "unprognostic (9.14e-2)" "unprognostic (2.38e-2)" "unprognostic (1.46e-1)" "unprognostic (1.54e-1)" "unprognostic (2.44e-1)" "unprognostic (1.40e-1)" "unprognostic (1.90e-1)" "unprognostic (5.82e-1)" "unprognostic (4.01e-1)" 1.1 1.1 3.0 0.7 2.7 0.0 1.0 0.0 6.2 1.1 0.0 0.8 0.4 1.1 0.4 2.2 0.8 1.2 13.3 0.2 3.5 2.3 0.3 0.4 0.4 2.9 5.8 3.4 0.5 0.3 1.0 3.9 2.1 0.9 1.0 0.3 0.9 0.4 35.8 2.0 1.0 1.0 1.7 1.6 4.5 0.7 9.6 0.3 0.8 12.5 0.7 1.0 1.2 1.8 0.1 0.9 0.0 0.0 0.3 0.2 0.0 0.3 3.1 0.3 1.9 1.2 0.0 0.0 0.7 0.2 0.5 0.2 0.7 0.0 0.0 0.0 0.2 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.1 1.5 6.1 0.0 0.0 0.0 0.0 0.0 3.4 0.6 0.3 0.0 1.0 1.1 0.0 0.0 0.0 0.1 2.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 2.7 0.0 6.2 0.2 3.5 2.9 5.8 2.1 1.7 9.6 1.8 2.3 0.0 0.5 2.3 0.1 0.0 0.1 0.0 1.2 14.9 0.1 1.3 8.5 0.0 0.6 0.0 14.6 0.0 0.7 0.1 0.0 0.0 3.0 2.1 1.4 0.8 4.2 0.0 3.0 0.2 0.0 2.0 2.0 4.9 0.0 0.0 1.1 0.0 0.1 0.0 89.0 0.1 0.0 0.0 0.0 5.2 4.1 0.7 0.0 2.8 0.0 0.5 0.0 0.5 0.9 0.0 0.0 2.2 0.3 0.1 0.0 0.2 0.0 21.9 19.7 4.3 14.7 0.1 0.8 0.2 0.0 0.1 0.3 1.1 0.0 0.0 GUCA2B ENSG00000044012 "Guanylate cyclase activator 2B" Q16661 1 42153410-42155820 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "intestine: 143.1" "Cell type enriched" "Detected in some" 7 "Paneth cells: 18841.5" "Cancer enhanced" "Detected in many" "liver cancer: 5.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "A549: 1.4;CACO-2: 3.8" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 1.0" "Secreted to blood" NA NA 77700 1200000 "Cluster 7: Monocytes - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" "unprognostic (2.59e-2)" "unprognostic (1.44e-2)" "unprognostic (1.34e-1)" "unprognostic (6.22e-2)" "unprognostic (1.86e-1)" 0.2 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 89.4 36.5 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 5.5 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 23.3 0.0 0.0 0.6 0.0 0.1 143.1 0.6 0.0 0.0 18.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 3.8 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.0 1098.8 0.0 0.9 1.0 0.0 0.0 0.0 22.8 0.0 0.0 47.9 0.3 0.0 0.0 0.0 22.3 0.0 0.4 3.1 0.1 0.0 0.0 107.2 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 18841.5 0.0 0.0 0.0 2568.9 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.4 1.3 0.0 55.3 0.9 HCK JTK9 ENSG00000101336 "HCK proto-oncogene, Src family tyrosine kinase" P08631 20 32052197-32101856 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Exocytosis, Host-virus interaction, Immunity, Inflammatory response, Innate immunity, Phagocytosis" "Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 112.1" "Cell type enhanced" "Detected in many" "Hofbauer cells: 150.7;Kupffer cells: 155.5;Langerhans cells: 89.2;Macrophages: 170.1;Microglial cells: 52.5;monocytes: 222.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "classical monocyte: 575.0;eosinophil: 707.8;intermediate monocyte: 1059.1;myeloid DC: 336.3;neutrophil: 801.3;non-classical monocyte: 1251.7" "Group enriched" "Detected in all" 16 "dendritic cells: 336.3;granulocytes: 801.3;monocytes: 1251.7" "Group enriched" "Detected in some" 9 "THP-1: 69.3;U-937: 199.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB005195, HPA035534, HPA063768" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "Plasma membrane, Cytosol" "CAB005195: AB_631619, HPA035534: , HPA063768: AB_2685118" "unprognostic (6.22e-2)" "unprognostic (6.16e-3)" "unprognostic (2.26e-2)" "unprognostic (7.98e-2)" "unprognostic (8.83e-2)" "unprognostic (5.50e-2)" "unprognostic (4.09e-2)" "unprognostic (1.72e-2)" "unprognostic (4.34e-2)" "unprognostic (1.59e-1)" "unprognostic (4.08e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (1.66e-4)" "unprognostic (4.92e-2)" "unprognostic (4.42e-2)" "unprognostic (6.95e-2)" "unprognostic (1.12e-1)" 24.8 9.2 4.7 100.0 5.0 55.2 6.0 5.5 6.0 5.5 13.7 12.8 15.2 3.1 2.6 6.7 7.6 14.4 4.8 4.7 6.2 4.7 14.1 46.0 38.6 9.9 6.8 2.5 4.5 2.1 3.1 20.9 8.3 4.0 13.6 0.5 5.1 4.7 1.6 5.8 17.8 25.3 8.1 112.1 6.7 2.3 8.4 14.5 2.8 6.9 39.3 32.8 4.1 12.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.9 0.0 0.1 0.1 1.3 0.0 0.0 0.1 0.0 4.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 15.6 0.0 0.1 0.1 4.9 0.4 0.0 0.0 0.4 0.2 0.6 0.0 0.0 0.3 0.0 0.5 0.0 0.2 0.7 0.0 69.3 0.0 0.0 0.3 0.0 0.1 1.9 0.3 10.3 0.0 199.6 0.0 6.4 575.0 707.8 1.1 1059.1 1.3 48.4 1.1 1.1 336.3 43.0 1.1 0.9 801.3 11.0 1251.7 30.4 1.2 566.4 4.7 5.0 5.5 6.0 4.7 6.2 9.9 6.8 8.3 8.1 8.4 12.0 0.6 6.4 14.0 0.0 17.1 3.1 4.0 0.2 0.6 0.1 0.4 1.3 2.0 1.5 3.9 7.3 0.0 0.9 12.1 0.2 1.9 0.1 2.5 0.1 0.1 3.7 1.8 1.7 1.2 0.6 0.9 1.3 4.6 0.1 6.3 0.1 1.1 2.3 150.7 0.0 1.0 0.5 22.4 155.5 89.2 0.3 0.0 170.1 1.8 52.5 222.0 0.0 4.1 1.5 0.6 0.0 0.0 0.0 0.7 0.5 0.1 0.3 1.5 0.1 0.0 0.6 0.5 0.2 0.3 0.2 1.1 1.6 3.0 0.2 0.9 3.7 HCLS1 "CTTNL, HS1" ENSG00000180353 "Hematopoietic cell-specific Lyn substrate 1" P14317 3 121631399-121660927 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 153.6;lymphoid tissue: 300.3" "Cell type enhanced" "Detected in many" "B-cells: 175.7;Kupffer cells: 666.3;Macrophages: 269.0;monocytes: 245.7;NK-cells: 216.3;T-cells: 181.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 265.6;HMC-1: 362.3;RPMI-8226: 256.5;THP-1: 262.8;U-266/70: 361.6;U-698: 371.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019143 Enhanced Supported "Plasma membrane,Cytosol" NA NA 870000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Cytosol" "HPA019143: AB_1850532" "unprognostic (2.27e-2)" "unprognostic (1.79e-3)" "unprognostic (5.38e-3)" "unprognostic (6.29e-2)" "unprognostic (1.01e-2)" "unprognostic (4.02e-3)" "unprognostic (2.35e-1)" "unprognostic (4.88e-3)" "unprognostic (1.70e-2)" "unprognostic (1.19e-1)" "unprognostic (6.76e-2)" "unprognostic (2.28e-1)" "unprognostic (1.03e-3)" "unprognostic (2.93e-1)" "unprognostic (3.46e-2)" "unprognostic (2.60e-2)" "unprognostic (2.01e-1)" 67.0 32.9 14.6 147.2 14.7 153.6 25.5 15.4 18.7 20.7 15.8 29.2 21.2 13.7 6.4 15.7 21.5 37.8 18.4 14.3 17.0 21.5 39.1 52.7 207.6 21.6 17.5 9.4 11.9 7.7 14.6 51.4 20.8 15.8 31.4 2.3 16.0 11.1 7.3 11.1 68.7 34.6 18.5 300.3 27.1 4.5 18.2 140.3 15.4 18.8 242.8 53.0 13.7 23.0 0.8 0.0 0.2 0.1 20.9 11.5 5.7 4.1 4.0 0.8 1.6 0.1 0.0 265.6 124.6 0.0 0.2 0.3 6.9 9.9 1.1 120.6 0.0 172.6 0.0 0.0 11.6 192.4 362.3 2.2 0.5 0.0 1.5 0.0 153.4 106.2 35.1 235.9 0.0 0.0 137.9 162.9 0.3 0.2 4.5 137.1 0.2 256.5 0.0 68.0 0.3 0.2 0.2 0.4 0.6 0.6 0.1 262.8 203.5 0.0 2.0 0.3 0.9 361.6 118.1 371.5 1.9 181.5 0.2 357.3 713.1 1180.9 405.3 870.4 333.0 345.7 334.2 376.8 636.2 313.1 279.3 326.2 1619.2 280.0 997.1 197.4 494.2 1427.9 14.6 14.7 15.4 18.7 14.3 17.0 21.6 17.5 20.8 18.5 18.2 23.0 23.0 9.6 31.8 1.0 175.7 3.2 1.0 7.8 0.6 0.5 2.7 5.1 2.3 4.3 13.1 0.0 0.0 122.4 139.5 0.8 0.0 0.3 1.1 8.8 1.6 23.3 0.0 50.5 1.4 0.2 60.0 7.0 8.6 3.1 73.4 0.7 27.8 7.7 126.9 0.0 0.7 0.4 4.1 666.3 105.8 1.5 3.4 269.0 19.6 26.2 245.7 0.4 216.3 0.5 0.3 0.2 0.2 1.2 148.6 0.4 0.1 0.9 24.7 0.8 13.1 3.7 6.7 0.6 0.6 1.3 4.4 145.4 181.4 2.4 0.5 2.2 HHLA2 "B7-H5, B7-H7, B7H7, B7y" ENSG00000114455 "HERV-H LTR-associating 2" Q9UM44 3 108296490-108378285 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "intestine: 129.9" "Cell type enhanced" "Detected in some" "Distal enterocytes: 274.7;Paneth cells: 64.2;Proximal enterocytes: 186.8" "Group enriched" "Detected in many" 12 "colorectal cancer: 9.2;lung cancer: 5.0;pancreatic cancer: 5.1;renal cancer: 16.6;stomach cancer: 6.2" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in single" "myeloid DC: 1.8" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "CACO-2: 1.7;HDLM-2: 4.0;Karpas-707: 2.8" "Low region specificity" "Detected in all" HPA055478 Enhanced NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA055478: AB_2682830" "unprognostic (1.12e-2)" "unprognostic (2.29e-1)" "unprognostic (1.03e-1)" "unprognostic (3.11e-1)" "unprognostic (2.30e-1)" "unprognostic (1.59e-2)" "unprognostic (8.14e-5)" "unprognostic (1.76e-1)" "unprognostic (2.28e-1)" "unprognostic (1.08e-1)" "unprognostic (6.42e-3)" "unprognostic (1.24e-1)" "unprognostic (1.62e-3)" "unprognostic (1.47e-1)" "unprognostic (2.31e-1)" "unprognostic (2.67e-1)" "unprognostic (1.66e-2)" 0.4 0.2 0.5 5.6 0.4 1.1 0.2 0.7 1.3 0.0 0.0 87.9 86.8 0.3 0.8 0.5 3.7 29.2 0.2 0.6 0.7 7.6 0.1 5.7 0.6 0.7 0.3 0.1 2.9 0.1 0.2 0.1 0.6 0.2 83.0 1.2 0.2 0.3 0.5 0.3 129.9 2.0 0.2 0.3 9.4 3.3 0.6 0.4 0.2 0.0 0.3 0.0 0.0 0.8 0.2 0.3 0.2 0.2 0.0 0.0 0.7 0.0 0.0 0.0 0.2 1.7 0.2 0.1 0.1 0.0 0.1 0.2 0.6 0.0 0.0 4.0 0.1 0.1 1.4 0.2 0.0 0.8 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 2.8 0.0 0.2 0.4 1.5 0.5 0.2 0.3 0.3 0.1 0.8 0.0 0.1 0.7 0.7 0.7 0.0 0.1 0.5 0.1 0.2 0.1 0.1 0.7 0.2 0.2 1.3 0.7 0.3 0.0 0.4 0.1 0.5 0.1 0.4 0.0 0.1 0.0 0.1 0.0 0.1 1.8 0.1 0.0 0.0 0.2 0.1 0.5 0.0 0.0 0.2 0.5 0.4 0.7 1.3 0.6 0.7 0.7 0.3 0.6 0.2 0.6 0.8 0.0 0.0 2.0 0.7 0.4 0.0 0.1 0.7 0.0 0.0 0.7 0.3 0.2 27.1 1.6 0.0 0.0 0.0 0.0 274.7 0.0 8.5 3.3 3.2 0.0 0.3 1.8 0.0 1.3 37.6 0.1 0.3 2.6 0.1 2.5 0.0 0.0 0.0 0.1 0.0 0.5 12.5 2.0 0.0 0.7 4.2 0.3 0.3 0.0 0.0 1.1 0.0 0.0 0.5 0.9 35.7 64.2 0.0 0.0 0.1 186.8 20.4 19.4 0.0 0.0 0.1 0.1 0.7 0.3 0.0 0.0 0.1 0.5 0.0 17.7 0.1 HJURP "DKFZp762E1312, FAKTS, hFLEG1, URLC9" ENSG00000123485 "Holliday junction recognition protein" Q8NCD3 2 233833416-233854566 "Predicted intracellular proteins" "Cell cycle" "Chaperone, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 47.4;lymphoid tissue: 30.4" "Cell type enhanced" "Detected in many" "Early spermatids: 17.4;Erythroid cells: 38.3;Extravillous trophoblasts: 16.1;Granulosa cells: 14.8;Spermatocytes: 37.5;Spermatogonia: 16.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "T-reg: 1.2" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA008436, HPA027261" Uncertain Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitochondria" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nucleoli, Nucleoli rim" Mitochondria "HPA008436: AB_1850757, HPA027261: AB_2672184" "unprognostic (5.63e-2)" "unprognostic (9.15e-2)" "unprognostic (1.87e-1)" "unprognostic (1.44e-3)" "unprognostic (3.62e-1)" "unprognostic (1.75e-1)" "prognostic unfavorable (3.37e-5)" "prognostic unfavorable (2.46e-4)" "prognostic unfavorable (6.49e-4)" "unprognostic (9.48e-2)" "prognostic unfavorable (7.72e-5)" "unprognostic (7.60e-2)" "unprognostic (0.00e+0)" "unprognostic (7.42e-2)" "unprognostic (5.58e-2)" "unprognostic (1.89e-2)" "unprognostic (5.74e-2)" 0.6 0.6 0.0 5.5 0.1 47.4 1.1 0.1 0.2 0.8 0.1 3.9 4.1 0.9 0.2 5.6 0.3 0.5 0.3 0.1 0.1 0.4 0.8 1.4 12.6 0.1 0.3 0.2 0.2 0.1 0.1 3.0 0.1 0.4 5.2 0.1 1.0 0.1 0.2 3.6 3.8 1.9 0.0 4.1 2.4 11.1 0.3 30.4 0.3 0.0 12.0 1.4 2.0 0.2 54.5 73.6 68.4 32.7 2.6 5.4 42.8 79.5 37.9 55.2 59.9 51.3 57.6 17.1 9.0 31.4 98.0 61.7 54.9 40.9 72.6 40.0 21.6 65.5 61.4 50.9 0.3 54.1 43.2 1.8 1.5 45.1 30.9 15.7 35.5 51.3 56.6 40.8 103.0 55.3 76.4 59.7 58.9 42.2 49.1 58.4 103.0 30.3 28.6 32.3 39.4 24.7 45.8 34.2 31.7 31.0 25.7 42.1 26.0 59.6 64.6 44.3 87.2 38.6 32.7 67.9 35.7 39.3 151.6 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.3 0.1 0.4 0.0 1.2 0.4 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.3 0.1 0.0 0.3 0.2 0.2 0.0 0.5 0.0 2.9 1.3 0.5 1.9 0.0 0.0 0.7 0.5 1.2 0.0 2.1 0.0 0.0 8.2 0.5 5.6 0.0 0.2 17.4 0.3 1.3 1.1 0.0 38.3 0.0 0.0 16.1 2.0 5.1 1.3 0.0 14.8 2.2 0.3 7.1 0.0 0.0 3.5 0.0 3.0 2.9 9.0 0.6 3.5 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.2 1.4 0.0 11.4 1.0 0.5 0.1 0.1 0.0 0.0 0.1 1.9 37.5 16.3 8.9 0.9 1.5 2.3 0.3 7.6 0.9 HMMR "CD168, RHAMM" ENSG00000072571 "Hyaluronan mediated motility receptor" O75330 5 163460203-163491941 "CD markers, FDA approved drug targets, Predicted intracellular proteins" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 20.6;lymphoid tissue: 27.3;testis: 27.5" "Cell type enhanced" "Detected in many" "Early spermatids: 86.2;Erythroid cells: 133.3;Extravillous trophoblasts: 55.1;Late spermatids: 60.9;Spermatocytes: 100.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "T-reg: 1.5" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "CAB002433, HPA040025, HPA043926, HPA061524" Enhanced Enhanced Microtubules,Centrosome,Cytosol Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Microtubules "Centrosome, Cytosol" "CAB002433: AB_564080, HPA040025: AB_2676805, HPA043926: , HPA061524: AB_2684551" "unprognostic (3.53e-3)" "unprognostic (1.01e-1)" "unprognostic (3.38e-3)" "unprognostic (8.88e-3)" "unprognostic (2.12e-1)" "prognostic unfavorable (5.52e-4)" "prognostic unfavorable (1.93e-7)" "prognostic unfavorable (1.09e-4)" "unprognostic (5.68e-2)" "unprognostic (2.50e-1)" "prognostic unfavorable (3.71e-5)" "unprognostic (1.02e-1)" "unprognostic (0.00e+0)" "unprognostic (1.65e-2)" "unprognostic (4.98e-2)" "unprognostic (2.39e-1)" "unprognostic (1.77e-2)" 0.8 0.7 0.2 10.1 0.3 20.6 2.1 0.3 0.4 1.1 0.1 6.6 7.4 0.8 0.2 4.0 0.5 0.9 0.8 0.2 0.2 0.7 1.7 0.9 18.1 0.5 0.3 0.2 0.3 0.9 0.2 6.2 0.4 0.5 8.8 0.8 0.8 0.2 1.2 4.2 6.5 2.9 0.3 2.9 3.6 27.5 0.7 27.3 0.7 0.4 17.7 2.2 1.4 0.5 77.0 47.2 94.5 50.8 5.0 9.0 70.3 71.4 34.9 88.0 78.9 96.8 145.1 127.5 66.0 22.2 118.5 86.3 112.4 69.0 148.6 116.1 34.4 76.7 32.3 48.4 1.4 68.7 67.3 2.4 4.1 82.8 64.0 14.7 50.6 85.7 73.2 101.0 93.2 28.5 72.3 38.8 81.9 51.2 51.6 78.0 126.3 63.9 34.8 20.4 78.8 43.8 106.3 32.8 38.6 45.1 97.3 54.5 32.9 63.2 52.4 50.6 97.2 53.7 96.3 102.4 41.4 104.2 61.1 0.2 0.2 0.0 0.1 0.1 0.3 0.3 0.3 0.1 0.2 0.2 0.1 0.2 0.1 0.5 0.0 0.6 1.5 0.2 0.2 0.3 0.3 0.4 0.2 0.2 0.5 0.3 0.4 0.3 0.7 0.5 0.4 0.0 1.1 1.3 6.0 2.5 1.8 4.5 2.8 0.6 3.2 3.7 2.5 4.3 3.2 0.0 0.0 37.3 2.3 5.3 0.0 0.8 86.2 3.8 3.1 3.1 1.2 133.3 0.6 0.2 55.1 4.6 11.7 5.7 0.0 21.6 5.3 3.8 22.2 0.0 0.4 7.8 6.1 8.8 2.7 60.9 2.1 7.6 0.0 0.0 2.3 0.1 1.0 0.5 1.2 0.2 0.3 0.7 22.9 1.5 1.3 2.6 2.8 1.0 6.6 0.6 3.8 100.9 23.3 14.1 1.4 4.5 5.2 1.6 15.6 3.0 IDH2 ENSG00000182054 "Isocitrate dehydrogenase (NADP(+)) 2" P48735 15 90083045-90102477 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glyoxylate bypass, Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "heart muscle: 492.6;skeletal muscle: 1302.3;tongue: 1611.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 732.5;Distal tubular cells: 1168.0;Extravillous trophoblasts: 586.7;Syncytiotrophoblasts: 573.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MOLT-4: 425.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007831 Enhanced Supported Mitochondria NA NA 5200000 "Cluster 51: Monocytes - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 14: REH - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "HPA007831: AB_1851397" "unprognostic (2.45e-2)" "prognostic favorable (5.15e-5)" "unprognostic (2.92e-1)" "unprognostic (1.53e-1)" "unprognostic (3.53e-1)" "unprognostic (8.46e-2)" "unprognostic (3.83e-2)" "unprognostic (2.55e-3)" "unprognostic (1.86e-2)" "unprognostic (1.89e-2)" "unprognostic (2.76e-1)" "unprognostic (4.90e-2)" "unprognostic (2.19e-3)" "unprognostic (3.92e-3)" "unprognostic (4.46e-1)" "unprognostic (1.30e-2)" "unprognostic (2.58e-2)" 32.8 10.5 56.5 60.2 67.8 161.1 51.1 57.1 59.8 36.6 76.6 95.9 97.2 29.0 12.5 140.6 32.7 31.7 492.6 47.2 55.0 208.3 274.7 32.0 77.1 61.0 61.3 13.6 128.7 104.0 15.5 87.3 54.4 76.2 84.1 5.4 163.1 90.4 1302.3 61.8 84.3 79.8 52.9 36.8 175.7 5.3 71.6 148.7 16.0 1611.3 66.0 53.3 49.4 57.6 61.3 33.5 169.9 169.8 23.3 28.3 144.5 74.5 110.8 68.0 72.6 16.1 51.1 72.7 21.0 61.2 65.1 20.8 25.1 22.4 32.0 143.8 16.9 122.9 12.7 119.7 28.1 85.1 118.2 59.7 12.7 16.3 13.0 82.1 141.0 246.4 18.9 59.3 53.0 175.3 425.0 131.2 51.8 81.9 14.3 352.0 122.4 213.7 105.6 71.3 244.5 125.3 92.1 359.8 29.9 94.2 290.9 256.9 34.0 120.4 17.0 16.1 34.9 101.5 20.5 9.0 38.4 175.0 71.2 45.0 112.8 75.6 105.9 199.1 53.2 70.1 77.0 120.1 136.9 47.7 42.9 71.8 22.9 99.9 252.1 79.4 72.4 163.4 56.5 67.8 57.1 59.8 47.2 55.0 61.0 61.3 54.4 52.9 71.6 57.6 16.9 6.4 21.0 40.1 64.2 39.9 98.8 91.6 12.5 6.2 90.5 48.1 445.9 114.4 95.8 75.4 10.4 732.5 84.0 70.0 1168.0 252.8 5.6 96.4 25.7 41.6 61.7 193.8 11.8 288.8 586.7 44.7 88.2 50.9 31.6 29.2 38.2 283.1 263.7 10.1 8.3 158.3 229.9 77.7 101.1 3.2 14.0 79.0 58.7 5.6 85.3 20.9 119.4 16.6 27.3 116.6 105.0 35.3 185.9 170.3 69.6 205.0 167.9 5.4 13.1 60.8 73.4 0.6 15.6 113.3 67.1 573.0 88.1 14.7 305.1 140.1 IGDCC4 "LOC57722, NOPE" ENSG00000103742 "Immunoglobulin superfamily DCC subclass member 4" Q8TDY8 15 65381484-65422947 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.3;skeletal muscle: 10.6;tongue: 14.0" "Cell type enhanced" "Detected in many" "Astrocytes: 18.6;Cone photoreceptor cells: 31.3;Fibroblasts: 14.7;Leydig cells: 34.8;Microglial cells: 14.0;Oligodendrocyte precursor cells: 17.6;Skeletal myocytes: 29.8" "Cancer enhanced" "Detected in many" "glioma: 6.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 4.4;AF22: 9.4;CAPAN-2: 8.1;EFO-21: 4.5;HSkMC: 5.2;NTERA-2: 7.2;SuSa: 5.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008510, HPA008576" Approved Approved Approved Nucleoplasm,Cytosol NA NA 64000000 "Cluster 80: Striated muscle - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" "HPA008510: , HPA008576: AB_1079496" "unprognostic (1.16e-1)" "unprognostic (9.38e-2)" "unprognostic (1.92e-2)" "unprognostic (1.20e-2)" "unprognostic (1.58e-1)" "unprognostic (1.77e-2)" "unprognostic (2.75e-3)" "unprognostic (9.94e-2)" "unprognostic (4.18e-2)" "unprognostic (3.65e-2)" "unprognostic (3.29e-2)" "unprognostic (6.36e-2)" "unprognostic (1.83e-8)" "unprognostic (3.30e-2)" "unprognostic (4.54e-2)" "unprognostic (2.33e-1)" "unprognostic (5.32e-3)" 0.9 2.5 5.6 2.4 6.9 0.0 0.5 5.8 2.5 3.4 0.0 0.8 0.5 1.4 4.2 1.6 1.7 4.2 0.9 2.9 7.2 0.1 0.0 0.2 0.6 11.2 9.4 8.5 0.1 0.3 0.9 5.6 6.8 0.4 0.6 0.8 0.5 0.4 10.6 0.8 0.8 1.0 6.9 0.2 1.1 0.6 11.3 0.7 1.9 14.0 0.6 2.1 2.0 4.5 0.0 4.4 9.4 0.0 0.0 1.0 0.0 0.4 0.0 0.0 0.3 0.5 8.1 0.0 4.5 0.3 0.0 0.0 2.3 0.0 0.1 0.0 0.5 0.0 0.0 0.2 0.3 0.0 0.0 5.2 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 1.7 0.0 0.0 0.8 7.2 0.0 0.0 0.0 2.3 0.0 3.3 0.0 0.0 0.1 0.0 0.0 0.4 5.4 0.0 0.0 0.0 3.7 2.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 6.9 5.8 2.5 2.9 7.2 11.2 9.4 6.8 6.9 11.3 4.5 0.2 0.0 0.0 18.6 0.0 2.3 0.0 0.0 0.0 7.7 0.2 0.5 2.2 0.0 0.0 3.7 31.3 0.4 0.1 0.0 0.0 0.4 0.4 0.0 2.1 0.3 0.0 0.0 0.9 0.0 0.6 14.7 1.1 0.0 0.0 8.8 0.0 0.0 0.7 0.0 6.3 0.0 0.0 0.0 2.5 1.4 34.8 0.3 5.4 14.0 0.0 1.0 1.0 17.6 1.0 0.3 0.0 4.1 0.1 0.1 0.0 0.7 0.0 12.2 6.6 29.8 1.0 0.8 2.6 0.1 1.1 0.8 0.3 7.0 0.0 0.0 IGSF9 "IGSF9A, KIAA1355, Nrt1" ENSG00000085552 "Immunoglobulin superfamily member 9" Q9P2J2 1 159927039-159945613 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 32.8;retina: 34.8;skin 1: 23.3" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 93.8;Distal enterocytes: 83.5;Gastric mucus-secreting cells: 37.8;Rod photoreceptor cells: 145.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 24.9;HaCaT: 37.0;NTERA-2: 18.9;SCLC-21H: 32.9;SH-SY5Y: 16.8;T-47d: 18.6" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "basal ganglia: 2.9;cerebellum: 5.5" HPA037753 Uncertain "Intracellular and membrane" NA NA 140000 "Cluster 85: Liver - Metabolism" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA037753: AB_10672915" "unprognostic (5.73e-2)" "unprognostic (2.86e-2)" "unprognostic (1.06e-2)" "prognostic unfavorable (5.16e-4)" "unprognostic (3.30e-2)" "unprognostic (6.06e-3)" "unprognostic (8.93e-3)" "unprognostic (1.37e-1)" "unprognostic (5.73e-2)" "unprognostic (2.05e-1)" "unprognostic (2.04e-2)" "unprognostic (2.15e-2)" "unprognostic (6.03e-3)" "unprognostic (2.87e-1)" "unprognostic (8.60e-2)" "unprognostic (1.42e-1)" "unprognostic (2.17e-2)" 4.4 0.0 0.1 0.6 0.4 0.2 2.1 0.1 0.3 2.6 0.0 9.8 7.4 0.8 2.0 10.0 4.6 0.4 0.9 0.1 0.5 1.4 32.8 0.5 0.0 0.2 0.2 0.7 1.7 1.6 0.6 0.2 0.2 6.0 4.3 34.8 5.7 3.5 0.0 23.3 9.6 0.3 0.0 0.2 12.8 5.0 0.5 1.8 1.4 0.0 0.7 1.8 6.3 0.2 8.6 0.0 3.3 0.0 0.0 0.0 24.9 0.0 0.0 0.0 0.0 12.1 4.2 0.0 0.3 0.1 0.0 37.0 1.8 5.1 0.0 0.0 0.1 0.6 0.6 0.0 0.0 0.0 0.0 0.0 15.9 0.3 0.5 0.0 0.0 1.5 0.4 0.0 0.0 15.9 0.3 0.0 18.9 14.4 4.0 0.0 0.0 1.5 0.0 11.6 32.9 16.8 1.1 14.3 0.0 3.3 18.6 0.0 0.0 0.0 6.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.1 0.3 0.1 0.5 0.2 0.2 0.2 0.0 0.5 0.2 0.1 0.0 0.0 0.3 0.1 13.4 3.7 8.2 6.8 11.6 5.6 6.2 1.8 10.0 3.4 0.0 93.8 1.3 0.0 83.5 0.0 4.5 19.8 7.8 0.9 1.3 8.3 0.0 0.0 33.8 3.2 1.2 37.8 13.7 0.0 1.9 0.4 19.6 0.2 1.7 0.0 7.9 4.1 0.3 2.8 3.4 0.3 0.4 0.0 0.0 0.0 5.1 0.0 0.0 0.1 29.0 12.5 0.0 0.1 2.1 24.1 0.1 3.4 145.8 0.0 0.2 0.4 0.6 1.8 6.4 12.5 0.7 0.2 0.7 7.4 1.7 INSM1 "IA-1, IA1" ENSG00000173404 "INSM transcriptional repressor 1" Q01101 20 20368104-20370949 "Predicted intracellular proteins, Transcription factors" "Cell cycle, Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 13.4;pituitary gland: 29.2" "Cell type enriched" "Detected in some" 42 "Enteroendocrine cells: 506.7" "Cancer enhanced" "Detected in many" "glioma: 9.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 19 "SCLC-21H: 370.4" "Low region specificity" "Detected in many" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "unprognostic (1.86e-2)" "unprognostic (5.25e-4)" "unprognostic (7.59e-2)" "unprognostic (3.49e-2)" "unprognostic (1.07e-1)" "unprognostic (1.07e-3)" "unprognostic (4.34e-2)" "unprognostic (2.89e-2)" "unprognostic (1.40e-1)" "unprognostic (2.38e-3)" "unprognostic (1.33e-1)" "unprognostic (1.52e-1)" "unprognostic (2.77e-1)" "unprognostic (1.33e-1)" "unprognostic (5.23e-1)" "unprognostic (1.22e-1)" 0.2 7.1 2.4 0.6 5.9 0.0 0.0 13.4 3.1 0.0 0.0 1.3 3.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 4.6 0.0 0.0 0.0 0.5 0.9 2.5 0.0 2.9 0.0 29.2 0.0 1.5 0.2 1.8 0.1 0.0 0.2 0.0 0.1 2.1 0.0 0.4 0.2 5.1 0.4 3.3 2.8 0.0 0.0 0.3 0.1 0.0 2.1 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 2.3 0.0 0.0 0.1 3.2 19.4 0.0 0.0 370.4 0.3 0.0 0.3 0.0 1.1 0.9 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.4 5.9 13.4 3.1 2.5 4.6 0.9 2.5 1.5 0.4 3.3 2.1 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.4 1.9 0.0 0.0 0.2 0.1 0.1 506.7 0.0 0.8 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 1.4 10.8 0.0 0.0 0.7 0.0 0.0 0.2 3.6 0.0 11.9 0.0 0.0 0.5 3.1 1.5 2.3 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.2 1.5 0.0 0.0 0.0 0.0 0.0 2.1 0.0 IQGAP3 ENSG00000183856 "IQ motif containing GTPase activating protein 3" Q86VI3 1 156525405-156572604 "Plasma proteins, Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 15.5" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 11.2;Late spermatids: 26.6;Undifferentiated cells: 7.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" "HPA030142, HPA030143" Uncertain Approved "Nucleoplasm,Nucleoli rim,Mitotic chromosome" Yes Yes "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoli rim" "Nucleoplasm, Mitotic chromosome" "HPA030142: AB_10600108, HPA030143: AB_10601104" "unprognostic (9.99e-3)" "unprognostic (5.24e-2)" "unprognostic (3.26e-1)" "unprognostic (1.55e-3)" "unprognostic (1.52e-1)" "unprognostic (4.69e-3)" "prognostic unfavorable (8.94e-6)" "unprognostic (1.86e-3)" "unprognostic (1.72e-1)" "unprognostic (1.98e-1)" "unprognostic (6.35e-3)" "unprognostic (1.03e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (4.46e-2)" "unprognostic (1.53e-1)" "unprognostic (6.30e-2)" "unprognostic (6.81e-2)" 0.7 0.7 0.2 2.2 0.4 15.5 0.6 0.0 0.6 1.1 0.2 4.1 6.6 0.5 1.1 5.2 0.2 0.7 0.4 0.5 0.1 0.6 0.6 1.6 1.6 0.9 0.4 0.1 0.2 0.1 0.1 2.8 0.9 0.4 5.0 0.0 1.0 0.1 0.3 3.7 5.7 2.9 0.0 0.8 4.6 3.8 0.6 3.4 0.2 0.0 2.2 0.9 2.1 0.4 59.2 28.4 25.6 18.1 1.6 4.0 12.4 43.1 28.3 41.0 36.6 32.4 52.5 5.2 15.6 25.2 21.6 54.6 17.5 22.1 36.3 0.1 15.7 7.8 62.6 16.1 0.2 9.7 0.1 1.2 2.5 34.3 50.0 10.0 24.1 12.5 16.1 8.1 30.2 31.2 5.7 13.7 18.6 57.7 28.0 18.9 28.8 6.1 10.4 20.3 16.3 25.2 38.7 44.9 14.9 29.8 35.8 25.6 16.8 36.8 43.7 30.4 51.4 4.0 2.1 2.4 12.4 15.1 42.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.0 0.2 0.4 0.0 0.6 0.5 0.1 0.9 0.4 0.9 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.4 1.3 0.1 0.4 0.6 0.0 1.4 1.3 1.0 2.8 0.1 0.0 0.0 2.2 0.1 3.9 0.0 0.3 6.5 0.5 0.7 0.6 1.2 6.5 0.7 0.0 3.6 0.9 11.2 1.4 0.0 4.4 2.5 0.4 3.9 0.0 0.2 3.7 0.0 1.3 6.1 26.6 0.3 1.9 0.0 1.0 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.0 0.5 0.4 0.8 0.4 0.0 0.0 0.0 0.0 1.4 6.4 2.6 3.6 1.0 0.8 0.2 0.3 7.4 0.4 KDR "CD309, FLK1, VEGFR, VEGFR2" ENSG00000128052 "Kinase insert domain receptor" P35968 4 55078481-55125595 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins" "Angiogenesis, Differentiation, Host-virus interaction" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 9 "Adipocytes: 157.8;Endothelial cells: 143.8;Hepatic stellate cells: 158.1;Muller glia cells: 206.6" "Cancer enhanced" "Detected in all" "renal cancer: 27.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "HUVEC TERT2: 74.8;TIME: 83.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004028, HPA073577" Enhanced Approved "Nuclear membrane,Vesicles" "Intracellular and membrane" NA NA 11000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 5: Muller glia cells - Visual perception" Vesicles "Nuclear membrane" "CAB004028: AB_2212507, HPA073577: " "unprognostic (1.61e-1)" "unprognostic (2.03e-1)" "unprognostic (9.65e-2)" "unprognostic (1.97e-1)" "unprognostic (9.63e-2)" "unprognostic (1.22e-2)" "unprognostic (1.78e-3)" "unprognostic (2.59e-2)" "unprognostic (1.19e-2)" "unprognostic (1.10e-1)" "unprognostic (8.79e-3)" "unprognostic (1.34e-1)" "prognostic unfavorable (7.26e-4)" "unprognostic (4.00e-2)" "unprognostic (2.30e-1)" "unprognostic (3.22e-1)" "unprognostic (1.86e-1)" 41.6 11.7 2.7 4.3 3.8 0.0 26.1 2.8 4.1 14.8 10.4 6.3 2.2 39.5 2.9 4.0 17.9 5.6 20.6 2.1 2.8 15.7 9.2 23.5 2.8 3.2 3.6 5.2 6.2 8.6 11.0 30.9 3.5 11.7 1.0 16.4 5.3 10.0 6.5 5.9 7.5 7.5 3.3 4.4 8.4 1.8 4.5 1.0 34.4 4.6 1.0 8.6 7.5 3.4 0.0 0.0 4.4 0.0 0.4 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 8.5 0.0 0.0 0.9 0.0 0.0 0.4 0.2 74.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.9 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 83.4 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 3.8 2.8 4.1 2.1 2.8 3.2 3.6 3.5 3.3 4.5 3.4 157.8 0.0 4.9 0.0 1.4 2.5 0.5 0.1 1.8 11.7 1.3 2.5 9.4 1.5 18.4 0.0 0.0 0.1 0.8 0.0 0.0 0.5 0.8 0.4 2.6 143.8 0.0 2.7 0.1 0.0 0.1 8.3 0.0 0.8 2.5 0.0 158.1 3.3 0.4 0.0 1.3 0.0 0.0 10.6 2.1 0.9 0.0 1.2 7.2 7.5 0.0 206.6 0.0 0.0 6.1 0.5 0.0 0.4 1.3 0.5 0.0 0.0 3.9 7.9 0.0 0.9 7.5 0.3 0.9 0.8 2.7 0.1 0.6 1.6 0.0 1.4 KIF14 KIAA0042 ENSG00000118193 "Kinesin family member 14" Q15058 1 200551497-200620751 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Motor protein" "Ciliopathy, Disease variant, Meckel syndrome, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.5;lymphoid tissue: 10.9" "Cell type enhanced" "Detected in many" "Erythroid cells: 27.1;Granulosa cells: 13.2;Spermatocytes: 22.8;Spermatogonia: 16.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA038061, HPA058220" Uncertain Supported "Midbody ring,Cytosol" Yes Yes "Cluster 18: Basophils - Vesicular transport" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "Midbody ring" "HPA038061: AB_10669515, HPA058220: AB_2683642" "unprognostic (1.84e-1)" "unprognostic (7.15e-2)" "unprognostic (2.00e-2)" "unprognostic (1.87e-2)" "unprognostic (2.74e-1)" "unprognostic (1.51e-1)" "unprognostic (1.18e-3)" "prognostic unfavorable (8.64e-4)" "unprognostic (8.47e-3)" "unprognostic (1.02e-1)" "unprognostic (2.54e-5)" "unprognostic (2.31e-2)" "unprognostic (0.00e+0)" "unprognostic (6.28e-3)" "unprognostic (3.31e-1)" "unprognostic (8.14e-2)" "unprognostic (7.44e-2)" 0.2 0.2 0.1 2.0 0.0 6.5 0.3 0.2 0.3 0.2 0.1 0.9 1.2 0.3 0.0 1.0 0.0 0.2 0.0 0.1 0.1 0.0 0.3 0.2 3.2 0.1 0.2 0.0 0.0 0.0 0.0 0.9 0.1 0.0 1.2 0.1 0.1 0.0 0.0 1.0 1.1 0.6 0.0 0.6 0.6 2.5 0.1 10.9 0.1 0.0 3.2 0.4 0.3 0.1 29.7 17.3 26.8 15.0 0.8 3.0 14.8 20.0 11.7 18.7 16.8 10.5 15.1 18.0 7.0 9.6 11.6 23.0 21.6 13.3 26.7 22.1 11.3 28.8 24.8 10.3 0.1 45.5 15.7 0.6 0.6 20.9 17.8 4.0 13.5 26.3 44.0 22.6 23.5 12.1 26.9 14.2 22.6 8.7 15.0 24.3 35.4 22.8 6.3 8.3 12.7 14.0 28.3 9.5 11.0 19.8 12.9 11.6 11.1 14.7 17.3 16.2 35.3 8.2 8.9 25.8 8.6 24.0 30.5 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.2 0.3 0.1 0.1 0.1 0.2 0.1 0.0 0.1 0.1 1.0 0.0 0.0 0.0 1.9 2.4 1.0 1.1 0.6 2.3 1.5 1.9 0.8 0.0 0.9 0.0 2.1 4.2 0.6 2.5 0.0 0.2 4.1 3.7 2.2 1.6 0.0 27.1 1.1 0.0 7.7 3.3 10.2 5.0 2.5 13.2 2.5 0.9 5.4 0.0 0.9 5.2 0.0 2.9 1.9 2.5 0.6 2.3 0.0 0.0 0.4 0.5 0.0 0.5 0.8 0.3 0.0 0.7 11.3 1.2 0.2 0.1 1.4 0.8 6.6 1.4 2.1 22.8 16.3 8.3 0.9 1.4 2.3 0.7 4.3 1.9 KIF22 "Kid, KNSL4, OBP-1, OBP-2" ENSG00000079616 "Kinesin family member 22" Q14807 16 29790719-29805384 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA-binding, Motor protein" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 88.5;lymphoid tissue: 73.0" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 288.7;Hepatocytes: 565.5;Proximal tubular cells: 194.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048213, HPA075670" Enhanced Supported "Nuclear speckles" NA Yes "Cluster 44: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 14: REH - Unknown function" "Cluster 2: Hepatocytes - Metabolism" "Nuclear speckles" "HPA048213: AB_2680316, HPA075670: " "unprognostic (3.71e-2)" "prognostic favorable (3.87e-8)" "unprognostic (1.86e-1)" "unprognostic (2.21e-3)" "unprognostic (1.25e-1)" "unprognostic (6.06e-3)" "unprognostic (5.06e-3)" "unprognostic (2.70e-1)" "unprognostic (2.70e-1)" "unprognostic (4.73e-2)" "unprognostic (7.84e-2)" "unprognostic (2.10e-2)" "unprognostic (2.21e-2)" "unprognostic (3.67e-2)" "unprognostic (2.62e-1)" "unprognostic (3.94e-2)" "unprognostic (1.67e-1)" 9.2 7.0 9.5 19.7 9.9 88.5 13.4 8.1 10.4 10.5 6.9 22.6 16.6 8.2 8.6 22.3 12.3 6.4 10.8 9.5 8.9 11.2 8.3 8.5 34.1 8.4 8.3 8.2 7.3 33.8 9.2 15.7 8.3 24.9 20.6 8.9 10.5 12.0 8.4 32.8 16.9 8.0 8.9 18.6 11.8 28.3 9.4 73.0 26.0 11.0 34.7 10.1 13.3 9.3 89.3 103.9 120.6 87.6 8.0 11.9 104.8 65.8 52.1 123.1 113.9 97.9 103.3 130.6 60.4 34.4 61.2 90.0 118.9 67.5 57.4 84.8 100.4 72.4 115.1 119.0 2.7 79.1 76.0 6.7 17.7 68.5 51.3 17.1 67.2 144.7 109.4 104.1 65.5 186.5 173.1 196.1 101.8 65.7 59.6 237.9 110.6 122.4 44.9 45.0 99.8 65.4 48.5 94.7 33.1 39.4 84.8 105.2 29.8 63.8 66.6 57.7 72.6 96.6 105.3 141.4 41.9 129.0 83.3 58.7 14.1 39.5 49.7 21.1 37.3 30.4 50.0 53.1 14.7 27.3 40.0 38.4 6.2 31.5 18.3 9.6 56.5 40.5 9.5 9.9 8.1 10.4 9.5 8.9 8.4 8.3 8.3 8.9 9.4 9.3 13.9 32.1 115.4 5.5 23.0 30.8 25.8 56.7 52.9 27.5 56.5 56.4 288.7 57.2 38.5 69.9 25.0 81.7 20.1 44.2 62.6 16.6 9.9 29.5 18.9 29.2 41.4 85.2 4.8 50.1 85.4 50.1 25.0 31.1 43.6 29.5 49.2 565.5 46.3 6.7 6.1 39.5 34.6 47.7 40.4 8.5 15.5 36.7 35.6 4.7 38.6 69.8 29.9 4.0 5.3 17.3 44.0 12.8 49.9 26.1 18.0 194.0 29.7 20.5 13.1 23.7 34.2 50.9 61.6 41.4 27.6 76.9 34.2 12.2 42.3 22.5 KNL1 "AF15Q14, CASC5, CT29, D40, hKNL-1, hSpc105, KIAA1570, MCPH4, PPP1R55, Spc7" ENSG00000137812 "Kinetochore scaffold 1" Q8NG31 15 40594020-40664342 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Cancer-related genes, Disease variant, Mental retardation, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "bone marrow: 5.3;lymphoid tissue: 7.4;testis: 16.9" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 8.5;Extravillous trophoblasts: 11.3;Granulosa cells: 22.8;Hofbauer cells: 7.1;Proximal tubular cells: 11.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "HPA026624, HPA049647" Enhanced Enhanced "Nucleoplasm,Nuclear bodies" Yes Yes "Cluster 21: B-cells - Adaptive immune response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nuclear bodies" "HPA026624: AB_10601696, HPA049647: AB_2680840" "unprognostic (5.35e-2)" "unprognostic (1.01e-1)" "unprognostic (5.59e-3)" "unprognostic (4.22e-2)" "unprognostic (1.59e-2)" "unprognostic (5.66e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (2.11e-4)" "unprognostic (2.06e-2)" "unprognostic (1.43e-1)" "unprognostic (3.20e-4)" "unprognostic (2.22e-2)" "unprognostic (1.93e-12)" "unprognostic (3.07e-2)" "unprognostic (3.08e-1)" "unprognostic (8.45e-2)" "unprognostic (7.36e-2)" 0.2 0.1 0.1 1.9 0.0 5.3 0.3 0.2 0.2 0.2 0.2 1.3 1.6 0.3 0.2 1.0 0.1 0.3 0.1 0.1 0.1 0.5 0.7 0.4 3.6 0.1 0.3 0.0 0.0 0.3 0.0 1.3 0.1 0.1 1.4 0.2 0.2 0.0 0.0 0.8 1.7 0.7 0.0 0.6 0.9 16.9 0.3 7.4 0.3 0.1 3.4 0.5 0.2 0.1 19.1 9.3 18.0 13.8 0.5 2.6 8.6 20.5 8.1 16.0 13.1 11.6 7.2 11.9 6.1 9.3 12.0 21.9 17.6 9.7 16.3 21.4 5.0 35.5 15.5 3.9 0.0 26.2 17.8 0.5 0.4 10.8 6.4 2.1 13.8 20.9 22.9 19.2 18.3 6.1 23.5 6.1 9.4 11.3 9.5 21.2 25.8 5.9 2.6 15.6 15.9 7.7 17.7 10.6 2.1 5.9 11.1 9.0 13.1 18.7 16.3 21.9 11.7 7.5 27.9 22.3 7.6 18.5 18.1 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.3 0.5 0.0 0.1 0.1 0.1 0.1 0.0 0.6 0.0 0.1 0.0 0.2 0.2 0.1 0.1 0.1 0.3 0.1 0.0 0.3 0.1 0.3 0.0 0.5 0.0 1.1 0.0 0.0 0.0 0.0 0.0 1.1 1.1 0.0 0.0 1.8 1.8 0.0 8.5 2.6 0.0 1.9 0.2 0.0 3.5 3.5 1.9 0.0 0.0 0.0 0.6 11.3 4.2 0.0 2.9 0.0 22.8 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 2.1 0.0 0.0 11.5 0.7 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 3.7 1.9 1.7 0.0 0.0 LAPTM5 ENSG00000162511 "Lysosomal protein transmembrane 5" Q13571 1 30732469-30757774 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 1285.7;lymphoid tissue: 672.2" "Group enriched" "Detected in many" 4 "B-cells: 872.9;dendritic cells: 340.2;granulocytes: 639.8;Hofbauer cells: 1150.4;Kupffer cells: 942.2;Langerhans cells: 489.6;Macrophages: 925.0;monocytes: 446.1;NK-cells: 562.3;T-cells: 432.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 554.0;HEL: 1053.2;HL-60: 676.4;HMC-1: 2382.4;REH: 785.2;U-698: 898.1;U-937: 542.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051293 Approved Approved Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" Cytosol "HPA051293: AB_2681424" "unprognostic (3.12e-2)" "prognostic favorable (3.40e-4)" "unprognostic (6.86e-2)" "unprognostic (4.05e-3)" "unprognostic (1.63e-1)" "unprognostic (8.45e-2)" "unprognostic (1.43e-1)" "unprognostic (3.76e-1)" "unprognostic (1.22e-3)" "unprognostic (2.30e-1)" "unprognostic (6.75e-2)" "unprognostic (1.60e-1)" "prognostic unfavorable (5.89e-5)" "unprognostic (9.47e-2)" "unprognostic (8.18e-3)" "unprognostic (5.98e-2)" "unprognostic (3.94e-2)" 144.7 82.1 47.6 443.0 49.7 1285.7 60.4 49.7 90.4 53.1 55.7 82.2 68.1 27.3 16.7 49.5 46.8 137.9 31.6 45.2 62.7 30.5 98.6 284.9 672.2 82.4 67.3 16.4 30.2 21.8 22.6 145.2 75.8 31.5 90.6 5.9 38.5 30.9 9.2 24.0 155.9 93.5 69.2 491.1 72.9 10.9 81.1 298.3 38.5 20.9 636.5 161.1 22.8 114.9 1.2 0.0 1.7 0.0 0.1 0.1 0.6 0.9 0.3 0.5 0.1 0.7 1.2 554.0 56.0 1.7 1.9 2.2 0.0 0.8 0.5 62.3 0.0 1053.2 0.0 1.6 0.9 676.4 2382.4 0.6 1.2 0.6 4.1 0.3 124.2 70.7 13.8 34.0 8.8 0.0 117.5 142.2 0.7 0.0 0.0 785.2 99.6 391.6 0.8 0.1 0.6 0.4 1.3 1.3 1.1 1.0 0.5 422.2 145.3 0.6 3.0 0.6 3.4 2.7 0.7 898.1 3.1 542.8 1.8 1094.2 1522.8 1446.7 538.5 1046.1 616.3 823.6 485.5 502.8 825.7 1089.4 481.2 481.2 1709.5 327.0 1075.7 392.7 656.9 2740.4 47.6 49.7 49.7 90.4 45.2 62.7 82.4 67.3 75.8 69.2 81.1 114.9 62.9 25.6 100.4 0.0 872.9 23.8 1.1 1.3 4.0 0.0 6.2 10.4 5.5 14.3 13.9 3.7 0.0 5.8 340.2 0.8 0.0 1.2 2.0 1.4 0.9 60.2 1.2 78.2 0.2 0.7 8.4 12.3 10.2 1.1 639.8 0.2 47.2 9.4 1150.4 0.0 0.8 0.9 0.0 942.2 489.6 4.9 1.5 925.0 49.8 43.1 446.1 0.3 562.3 0.5 0.5 1.4 0.2 0.4 144.8 0.9 0.5 3.0 11.4 1.3 0.0 4.1 5.6 0.3 1.1 1.8 20.0 8.9 432.7 18.2 2.4 1.9 LGALS4 GAL4 ENSG00000171747 "Galectin 4" P56470 19 38801671-38812945 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "intestine: 1307.1" "Group enriched" "Detected in many" 4 "Distal enterocytes: 4349.4;Intestinal goblet cells: 3767.6;Paneth cells: 3353.0;Proximal enterocytes: 4572.2;Undifferentiated cells: 2684.6" "Group enriched" "Detected in many" 21 "colorectal cancer: 450.7;liver cancer: 133.6;pancreatic cancer: 213.7;stomach cancer: 190.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 205 "OE19: 987.1" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "CAB025653, HPA031184, HPA031185, HPA031186" Enhanced Uncertain "Plasma membrane" NA NA 200000 "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "CAB025653: , HPA031184: AB_2673776, HPA031185: AB_2673777, HPA031186: AB_2673778" "unprognostic (1.11e-1)" "unprognostic (1.12e-1)" "unprognostic (2.57e-3)" "unprognostic (7.88e-2)" "unprognostic (1.12e-1)" "unprognostic (1.61e-2)" "unprognostic (5.01e-2)" "unprognostic (5.34e-2)" "unprognostic (1.54e-1)" "unprognostic (7.58e-2)" "unprognostic (3.80e-2)" "unprognostic (1.48e-2)" "prognostic unfavorable (2.28e-4)" "unprognostic (1.69e-1)" "unprognostic (3.38e-1)" "unprognostic (9.71e-2)" "prognostic favorable (3.21e-4)" 1.6 0.5 0.3 86.1 0.4 0.5 5.5 0.5 0.6 1.4 0.2 1307.1 812.2 3.2 0.2 1.4 2.4 137.1 0.9 0.3 0.3 2.9 79.5 1.2 1.1 0.3 0.3 1.6 31.5 0.0 0.8 0.2 0.3 2.3 933.0 0.2 1.1 2.3 1.6 1.6 691.9 55.2 0.2 4.0 135.2 0.9 0.3 0.3 1.7 0.2 0.4 11.2 1.5 0.4 0.0 0.4 0.1 0.0 0.3 0.0 1.3 0.0 0.0 0.0 0.0 1.3 0.1 0.3 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.1 2.2 0.0 987.1 0.0 0.1 0.0 2.5 0.1 4.8 0.2 1.4 0.1 0.1 0.0 0.0 0.1 1.0 0.0 0.0 0.2 1.0 0.0 0.2 0.2 0.1 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.5 0.6 0.3 0.3 0.3 0.3 0.3 0.2 0.3 0.4 1.7 3.2 6.5 0.7 10.3 1.1 3.0 0.6 3.4 1.1 3.6 3.0 1.3 770.7 1.0 0.0 0.0 0.8 0.9 4349.4 0.0 267.1 0.2 1.9 1.8 1.2 649.7 0.0 0.3 103.3 0.5 0.8 310.4 5.7 49.0 0.8 1.8 69.0 0.1 1.7 0.3 3767.6 0.0 1.9 0.3 0.0 0.0 1.2 0.0 1.0 3.0 0.8 1.0 0.0 0.7 492.7 3353.0 0.4 0.7 1.8 4572.2 9.3 0.4 2.3 0.0 3.9 1.1 0.3 0.9 0.9 2.7 0.5 11.1 1.1 2684.6 42.4 LIPF "HGL, HLAL" ENSG00000182333 "Lipase F, gastric type" P07098 10 88664441-88678814 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 142 "stomach 1: 37213.5" "Cell type enriched" "Detected in some" 444 "Gastric mucus-secreting cells: 1509.7" "Cancer enriched" "Detected in some" 75 "stomach cancer: 278.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 4.1;MOLT-4: 3.4;NTERA-2: 3.4;REH: 2.1;RPMI-8226: 1.8;THP-1: 6.8;U-2 OS: 2.2;U-266/70: 3.1" "Region enriched" "Detected in single" 77 "olfactory bulb: 7.6" HPA045930 Enhanced "Secreted to digestive system" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 4: Stomach - Digestion" "Cluster 3: HMC-1 - Innate immune response" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA045930: AB_10959518" "unprognostic (1.53e-1)" "unprognostic (1.83e-1)" 6.3 2.8 0.0 0.0 0.0 0.0 4.6 0.1 0.0 3.9 0.0 13.0 262.0 1.9 0.0 117.9 5.4 0.0 3.2 0.0 0.0 11.4 4.9 7.3 0.0 0.3 0.1 2.2 4.5 0.0 7.3 0.5 0.1 6.7 0.0 0.0 2.6 0.0 1.6 2.0 1.9 0.0 0.0 2.6 37213.5 2.9 0.0 0.0 1.3 0.0 0.1 2.5 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 3.4 0.0 0.0 2.1 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.0 2.2 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1509.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 LRRC25 "FLJ38116, MAPA" ENSG00000175489 "Leucine rich repeat containing 25" Q8N386 19 18391137-18397622 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 32.4;lymphoid tissue: 61.2" "Group enriched" "Detected in some" 6 "Hofbauer cells: 47.0;Kupffer cells: 123.6;Macrophages: 90.0;monocytes: 74.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "classical monocyte: 320.6;eosinophil: 356.2;intermediate monocyte: 512.1;myeloid DC: 229.3;neutrophil: 573.0;non-classical monocyte: 706.7" "Group enriched" "Detected in all" 60 "dendritic cells: 229.3;granulocytes: 573.0;monocytes: 706.7" "Cell line enhanced" "Detected in some" "Hep G2: 1.0;HMC-1: 1.8;THP-1: 1.7;U-937: 1.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA029459 Approved Approved "Endoplasmic reticulum,Microtubules,Cytosol" NA NA 630000 "Cluster 51: Monocytes - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Endoplasmic reticulum, Microtubules, Cytosol" "HPA029459: AB_10610005" "unprognostic (2.72e-2)" "unprognostic (6.08e-2)" "unprognostic (1.76e-2)" "unprognostic (2.07e-1)" "unprognostic (3.77e-2)" "unprognostic (9.15e-2)" "unprognostic (5.80e-2)" "unprognostic (1.23e-1)" "unprognostic (1.20e-2)" "unprognostic (4.63e-2)" "unprognostic (2.02e-1)" "unprognostic (1.73e-1)" "unprognostic (1.19e-3)" "unprognostic (5.77e-2)" "prognostic unfavorable (6.93e-4)" "unprognostic (1.74e-1)" "unprognostic (1.14e-1)" 9.4 9.4 2.4 21.8 2.5 32.4 3.1 3.3 2.9 1.8 3.2 3.3 3.7 1.6 0.7 2.3 3.9 5.3 2.5 2.3 3.1 2.4 5.9 11.5 9.9 4.6 4.0 1.5 2.0 0.7 1.2 5.4 4.2 2.0 2.8 0.3 2.6 1.2 3.7 1.0 4.8 6.7 2.8 61.2 2.3 1.2 5.4 3.0 1.2 8.7 4.0 7.0 1.3 4.7 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.7 0.3 1.0 0.8 0.4 1.8 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.4 0.2 0.1 0.0 0.1 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 1.7 0.4 0.2 0.1 0.1 0.1 0.1 0.0 0.0 0.2 1.5 0.1 55.4 320.6 356.2 0.9 512.1 1.9 7.3 0.6 0.7 229.3 8.4 0.5 0.6 573.0 4.6 706.7 32.1 1.3 229.2 2.4 2.5 3.3 2.9 2.3 3.1 4.6 4.0 4.2 2.8 5.4 4.7 0.7 0.0 1.3 0.0 5.0 0.0 0.1 0.1 0.0 0.1 0.3 1.0 0.3 0.0 0.7 0.0 0.0 0.1 2.9 0.1 5.9 0.1 1.9 0.2 0.1 0.9 0.0 2.1 0.1 0.0 0.4 0.5 0.0 0.4 10.2 0.0 1.8 0.5 47.0 0.0 0.1 0.0 0.0 123.6 12.5 0.5 0.0 90.0 1.8 1.0 74.9 0.0 6.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 2.4 0.2 0.0 0.2 0.0 0.1 0.4 1.1 0.2 0.1 0.1 LSP1 WP34 ENSG00000130592 "Lymphocyte specific protein 1" P33241 11 1850904-1892267 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 224.7;lymphoid tissue: 245.0" "Cell type enhanced" "Detected in many" "Hofbauer cells: 492.2;Langerhans cells: 553.6;monocytes: 1505.6;NK-cells: 352.2;Plasma cells: 338.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 278.5;HDLM-2: 978.9;Karpas-707: 215.4;RPMI-8226: 500.2;U-937: 173.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017781, HPA019693" Enhanced NA NA 1600000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "CAB017781: , HPA019693: AB_1853387" "unprognostic (7.53e-3)" "prognostic favorable (3.56e-4)" "unprognostic (4.35e-2)" "prognostic favorable (2.54e-4)" "prognostic unfavorable (5.35e-4)" "unprognostic (1.43e-3)" "unprognostic (3.82e-2)" "unprognostic (3.22e-1)" "unprognostic (1.13e-1)" "unprognostic (1.14e-1)" "unprognostic (6.10e-2)" "unprognostic (1.72e-1)" "unprognostic (1.03e-3)" "unprognostic (3.29e-1)" "unprognostic (6.33e-2)" "unprognostic (1.40e-1)" "unprognostic (6.20e-2)" 75.6 224.7 2.1 148.8 2.6 167.3 51.2 2.4 6.4 63.8 5.3 39.2 33.6 36.8 3.8 42.5 41.7 32.6 48.2 3.8 3.4 6.4 12.1 49.8 154.8 6.0 2.6 5.3 10.7 3.8 7.4 21.8 4.5 13.4 22.3 1.0 52.8 8.1 28.4 98.0 76.6 12.5 4.3 245.0 52.1 8.1 6.0 65.5 24.7 29.4 85.0 83.7 51.4 11.6 0.3 1.2 0.0 0.0 41.0 125.2 0.4 0.0 0.0 0.0 0.0 0.1 0.2 278.5 1.5 0.2 0.3 0.4 0.0 0.0 0.0 978.9 0.0 0.5 0.2 0.4 7.9 1.0 0.9 32.0 0.5 0.1 1.3 0.4 0.1 2.2 0.9 215.4 24.7 0.1 19.6 28.2 0.5 0.0 0.0 1.1 13.6 500.2 0.0 0.0 0.4 3.3 0.2 0.0 0.3 0.0 0.3 0.9 0.5 0.7 4.6 0.3 0.8 1.0 0.7 38.4 0.4 173.0 0.3 365.1 803.6 785.5 384.3 863.3 222.6 452.1 249.1 346.8 896.6 298.8 161.3 260.8 1574.3 279.6 888.2 669.7 491.4 1293.0 2.1 2.6 2.4 6.4 3.8 3.4 6.0 2.6 4.5 4.3 6.0 11.6 18.3 16.0 7.9 0.0 312.8 118.3 14.0 43.0 76.8 0.8 3.9 4.3 2.7 8.6 37.6 3.7 0.0 3.6 295.4 0.4 1.9 1.3 3.4 1.2 13.3 11.4 1.2 40.6 0.2 8.9 4.4 160.4 15.3 1.4 12.6 0.9 11.0 2.3 492.2 1.7 0.2 0.8 16.2 118.4 553.6 7.8 89.8 310.9 65.8 0.0 1505.6 0.2 352.2 0.5 0.1 1.4 1.4 30.1 338.4 1.1 1.2 12.9 36.6 1.0 0.0 182.1 15.9 0.4 1.3 16.7 114.7 6.4 310.1 92.7 3.2 67.3 LUM "LDC, SLRR2D" ENSG00000139329 Lumican P51884 12 91102629-91111494 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 739.0;placenta: 535.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 966.4;Fibroblasts: 2136.1;Leydig cells: 401.7" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in some" 4 "cerebral cortex: 5.6" "Immune cell enriched" "Detected in single" 122 "basophil: 12.1" "Lineage enriched" "Detected in single" 122 "granulocytes: 12.1" "Cell line enriched" "Detected in some" 5 "BJ hTERT+: 1991.0" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 9 "spinal cord: 149.2" "HPA001522, CAB025783" Supported "Secreted to extracellular matrix" NA NA 29000000000 "Cluster 38: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "CAB025783: , HPA001522: AB_1079285" "unprognostic (5.54e-2)" "unprognostic (2.27e-1)" "unprognostic (3.32e-1)" "unprognostic (2.75e-1)" "unprognostic (1.65e-1)" "unprognostic (8.38e-2)" "unprognostic (1.09e-1)" "unprognostic (2.87e-1)" "unprognostic (4.08e-2)" "unprognostic (1.19e-1)" "unprognostic (1.65e-2)" "unprognostic (2.20e-2)" "prognostic unfavorable (1.75e-6)" "unprognostic (5.25e-3)" "unprognostic (2.27e-2)" "unprognostic (2.38e-2)" "unprognostic (2.06e-2)" 161.5 133.5 0.6 68.1 0.7 0.3 153.2 0.6 5.6 199.8 4.2 85.0 56.1 301.0 88.3 75.7 59.2 739.0 183.8 0.7 0.9 85.0 34.6 211.4 41.3 0.9 0.8 92.9 72.9 26.3 5.3 535.9 0.8 115.2 133.0 5.7 14.3 67.4 9.6 20.0 90.6 354.5 0.7 4.8 47.1 17.5 1.3 13.4 30.8 73.0 80.3 486.0 39.2 0.8 0.0 0.3 6.9 0.0 237.4 115.9 0.7 400.8 1991.0 16.0 24.3 0.0 0.1 0.0 0.0 339.9 0.0 0.6 0.0 0.0 5.4 0.0 0.0 0.0 21.5 0.0 183.7 0.6 0.1 160.5 0.0 33.7 1.0 0.9 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.6 1.2 0.0 0.9 0.0 0.2 0.1 0.0 0.0 0.3 14.9 0.1 0.0 10.8 16.3 0.0 0.0 0.0 17.0 4.5 14.3 0.0 0.2 0.0 0.0 8.8 0.1 0.0 12.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.7 0.6 5.6 0.7 0.9 0.9 0.8 0.8 0.7 1.3 0.8 77.5 12.8 30.9 0.0 0.6 97.6 1.2 0.8 3.4 0.2 9.4 8.6 15.2 0.0 5.0 0.0 2.1 44.9 4.0 0.1 0.0 0.7 3.5 27.0 966.4 27.2 0.0 0.0 0.0 0.0 38.9 2136.1 8.6 15.2 18.3 0.0 55.0 0.3 63.6 0.0 0.2 0.3 0.0 0.3 143.5 8.7 401.7 9.5 117.4 16.9 1.0 86.9 0.0 0.0 0.0 2.1 0.0 44.8 6.3 4.9 0.4 0.3 0.8 3.0 0.0 39.1 165.5 0.2 0.9 5.9 100.2 84.0 14.5 27.4 0.0 4.1 LY86 "dJ80N2.1, MD-1" ENSG00000112799 "Lymphocyte antigen 86" O95711 6 6588108-6654983 "Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 78.4" "Group enriched" "Detected in many" 9 "B-cells: 124.9;Hofbauer cells: 191.7;Kupffer cells: 199.1;Langerhans cells: 118.6;Macrophages: 149.8;Microglial cells: 105.9;monocytes: 155.6" "Cancer enhanced" "Detected in all" "glioma: 22.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 426.6;myeloid DC: 426.1" "Group enriched" "Detected in all" 43 "B-cells: 335.1;dendritic cells: 426.1;monocytes: 426.6" "Cell line enhanced" "Detected in some" "Daudi: 69.5;NB-4: 44.7;RPMI-8226: 245.0;THP-1: 103.8;U-937: 45.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB025000, HPA044895" Approved "Secreted to blood" NA NA 77000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 57: B-cells - Immune response" "CAB025000: , HPA044895: AB_2679138" "unprognostic (1.82e-1)" "unprognostic (2.49e-3)" "unprognostic (2.01e-2)" "unprognostic (7.88e-2)" "unprognostic (2.15e-1)" "unprognostic (1.93e-1)" "unprognostic (2.53e-1)" "unprognostic (1.46e-3)" "unprognostic (3.52e-2)" "unprognostic (3.17e-1)" "unprognostic (1.69e-1)" "unprognostic (1.16e-1)" "unprognostic (5.82e-2)" "unprognostic (1.17e-1)" "prognostic unfavorable (5.61e-4)" "unprognostic (1.11e-1)" "unprognostic (4.20e-2)" 9.7 10.3 14.0 30.9 13.5 29.2 7.4 14.7 22.0 8.2 14.2 7.6 4.9 3.8 2.8 3.1 4.3 14.6 2.9 13.5 15.8 3.1 13.3 29.7 72.1 17.8 15.4 3.3 3.0 3.4 2.3 14.5 18.7 3.8 11.1 1.2 5.5 6.2 0.7 3.4 16.8 11.1 17.8 52.7 6.2 1.8 18.0 15.1 1.5 1.1 78.4 15.6 1.1 24.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 69.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 44.7 0.0 0.0 0.0 8.0 0.0 245.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 103.8 0.2 0.0 0.1 0.0 0.0 0.0 0.0 30.3 0.0 45.8 0.0 4.1 426.6 3.5 1.0 234.9 0.7 335.1 1.1 1.1 426.1 248.8 4.7 2.7 9.1 5.3 88.3 16.3 1.8 221.1 14.0 13.5 14.7 22.0 13.5 15.8 17.8 15.4 18.7 17.8 18.0 24.8 1.2 0.0 15.0 1.6 124.9 2.0 0.0 0.0 0.0 0.0 0.9 3.7 1.5 1.5 1.3 0.0 0.0 1.4 9.8 0.0 0.0 0.0 3.4 0.4 0.1 5.4 0.0 3.8 3.8 0.0 1.8 2.1 0.0 0.0 1.3 0.0 4.2 1.3 191.7 0.0 0.6 0.3 0.0 199.1 118.6 15.4 0.3 149.8 0.0 105.9 155.6 0.0 4.1 0.5 0.2 0.0 0.0 0.0 1.2 0.0 0.0 0.2 0.7 0.4 6.6 0.4 0.2 5.3 0.2 0.3 2.4 1.9 3.6 0.0 0.2 0.2 MAD2L1 "HSMAD2, MAD2" ENSG00000164109 "Mitotic arrest deficient 2 like 1" Q13257 4 120055623-120066858 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.9;lymphoid tissue: 5.7" "Cell type enhanced" "Detected in many" "Erythroid cells: 81.8;Extravillous trophoblasts: 119.2;Spermatocytes: 127.8;Spermatogonia: 76.2" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003348 Uncertain Approved Nucleoplasm NA Yes "Cluster 20: T-cells - T-cell receptor" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA003348: AB_10603014" "unprognostic (4.08e-3)" "unprognostic (7.31e-2)" "unprognostic (5.17e-3)" "unprognostic (1.10e-2)" "unprognostic (1.27e-1)" "unprognostic (5.54e-2)" "prognostic unfavorable (5.15e-5)" "prognostic unfavorable (2.17e-4)" "unprognostic (6.74e-3)" "unprognostic (1.47e-1)" "unprognostic (3.20e-3)" "unprognostic (3.87e-3)" "prognostic unfavorable (3.07e-11)" "unprognostic (3.06e-2)" "unprognostic (4.05e-1)" "unprognostic (1.03e-1)" "unprognostic (9.70e-2)" 0.3 0.4 0.5 2.1 0.6 5.9 1.2 0.8 0.7 0.5 0.2 2.2 1.8 0.7 0.3 1.6 1.4 0.4 0.5 0.5 0.5 0.4 0.5 0.4 4.0 0.4 0.4 0.5 0.2 0.4 0.1 1.4 0.5 0.6 2.6 1.0 0.3 0.5 0.2 1.0 1.9 0.8 0.4 0.8 0.9 2.3 0.4 5.7 0.4 0.2 3.6 0.7 0.5 0.6 27.2 11.6 26.9 17.5 2.8 3.4 11.5 21.0 11.8 21.5 16.5 15.7 16.3 39.6 6.8 7.6 9.5 7.1 27.1 16.1 30.0 18.8 18.8 22.0 10.5 14.9 0.8 36.3 12.0 1.9 2.3 14.6 9.1 5.4 12.6 16.4 26.7 22.0 11.4 12.0 35.0 15.6 18.3 14.1 13.0 17.8 35.9 16.2 8.7 10.3 28.4 20.1 10.5 12.8 6.5 12.9 8.4 13.0 7.8 14.2 16.1 14.6 27.0 20.1 23.2 25.7 13.3 18.4 19.1 0.9 0.1 0.1 0.4 0.1 0.6 0.5 1.2 1.0 0.1 0.4 1.1 1.1 0.3 0.9 0.2 0.7 1.3 0.5 0.5 0.6 0.8 0.7 0.5 0.5 0.4 0.4 0.5 0.4 0.4 0.6 2.4 0.0 1.3 1.0 11.5 17.3 7.3 23.5 4.0 9.7 7.2 8.3 3.4 1.5 6.0 7.3 2.1 52.0 7.6 7.5 0.0 3.4 2.4 31.3 6.0 5.4 1.8 81.8 1.3 1.5 119.2 13.7 8.6 7.8 15.2 34.6 3.9 2.9 27.9 20.2 1.2 13.7 36.7 7.3 13.4 4.8 4.7 6.1 8.8 0.0 3.1 12.3 5.2 0.5 1.0 1.6 3.7 1.5 33.1 5.0 3.7 7.2 12.9 3.8 13.1 7.3 14.9 127.8 76.2 26.0 8.9 10.8 20.1 11.9 29.2 8.7 MARCHF4 "KIAA1399, MARCH-IV, MARCH4, RNF174" ENSG00000144583 "Membrane associated ring-CH-type finger 4" Q9P2E8 2 216257865-216372483 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 4 "brain: 4.4;pituitary gland: 6.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "pancreatic cancer: 1.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 69.0;fHDF/TERT166: 43.8;TIME: 32.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA014348 Approved NA NA "Cluster 65: Brain - Ion transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA014348: AB_1853578" "unprognostic (4.84e-2)" "unprognostic (1.02e-4)" "unprognostic (1.63e-1)" "unprognostic (5.42e-2)" "unprognostic (3.31e-2)" "unprognostic (1.88e-1)" "unprognostic (1.38e-1)" "unprognostic (1.26e-2)" "unprognostic (1.24e-2)" "unprognostic (6.49e-2)" "unprognostic (5.55e-3)" "unprognostic (1.07e-1)" "unprognostic (6.81e-5)" "unprognostic (4.82e-2)" "unprognostic (2.06e-1)" "unprognostic (1.23e-1)" "unprognostic (1.09e-3)" 0.0 0.7 2.6 0.0 3.9 0.0 0.0 0.0 4.4 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.6 0.0 0.0 3.1 2.2 0.0 0.0 0.0 0.0 0.5 4.1 0.0 0.4 0.0 6.2 0.6 1.1 0.0 0.2 0.6 0.0 0.0 0.0 0.1 0.2 0.0 2.7 0.0 1.3 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 12.5 2.5 0.0 0.0 0.2 1.6 0.0 69.0 23.2 14.5 5.1 0.1 1.0 0.0 10.5 43.8 24.2 0.1 0.0 26.7 14.1 0.0 0.0 5.1 0.0 0.0 3.4 0.0 0.0 0.1 0.0 13.3 19.6 9.3 19.0 0.0 0.0 0.0 22.6 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 11.4 1.9 0.1 0.0 0.0 2.2 0.0 0.0 32.7 22.7 23.9 0.1 18.6 0.0 0.0 0.0 5.2 0.0 16.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 3.9 0.0 4.4 3.1 2.2 0.5 4.1 1.1 2.7 1.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MCM4 "CDC21, CDC54, hCdc21, MGC33310, P1-Cdc21" ENSG00000104738 "Minichromosome maintenance complex component 4" P33991 8 47960185-47978160 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 63.2" "Cell type enhanced" "Detected in many" "Early spermatids: 153.2;Erythroid cells: 60.8;Late spermatids: 77.9;Spermatocytes: 65.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004497, HPA004873, HPA031052" Enhanced Enhanced Nucleoplasm NA Yes 140000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB004497: AB_627916, HPA004873: AB_1079337, HPA031052: AB_2673712" "unprognostic (4.55e-2)" "unprognostic (3.16e-3)" "prognostic favorable (2.19e-4)" "prognostic unfavorable (2.84e-5)" "unprognostic (7.71e-2)" "unprognostic (1.05e-1)" "prognostic unfavorable (1.23e-4)" "unprognostic (1.12e-3)" "prognostic unfavorable (1.15e-4)" "unprognostic (2.65e-2)" "prognostic unfavorable (2.38e-4)" "unprognostic (5.16e-2)" "prognostic unfavorable (2.61e-4)" "unprognostic (3.53e-2)" "unprognostic (2.90e-1)" "unprognostic (1.70e-2)" "unprognostic (1.40e-1)" 6.5 8.8 4.8 21.7 4.8 63.2 16.0 5.7 5.2 7.7 1.8 17.7 13.3 6.9 4.6 22.4 9.7 5.6 14.5 5.2 3.5 8.2 9.2 6.3 38.7 3.6 4.2 7.1 5.5 7.7 4.1 18.3 3.9 5.6 21.3 12.3 8.8 4.9 13.4 24.2 16.7 9.2 4.2 8.1 10.6 41.6 4.8 47.0 6.5 15.8 41.8 11.8 10.9 5.2 184.0 139.6 188.1 83.2 20.7 36.6 102.8 122.6 99.8 178.5 190.3 156.6 181.1 229.8 70.3 72.1 119.2 143.2 278.7 128.2 199.8 64.2 190.4 371.8 133.3 169.2 5.4 189.7 82.0 20.3 24.1 147.8 54.3 28.6 72.0 136.8 216.2 167.0 129.9 155.6 435.5 141.5 241.2 246.5 54.2 266.6 159.6 139.2 64.9 168.1 209.0 97.8 325.6 133.6 46.3 117.7 154.9 110.5 45.1 138.1 125.4 144.5 131.9 54.7 104.6 347.2 114.8 185.7 131.5 2.3 1.8 1.1 4.0 3.1 2.0 3.9 3.8 5.4 3.9 1.6 3.3 2.7 0.1 4.1 3.5 1.5 10.2 3.6 4.8 4.8 5.7 5.2 5.2 3.5 3.6 4.2 3.9 4.2 4.8 5.2 3.3 0.0 6.3 3.3 6.5 21.7 11.1 9.0 13.6 12.2 9.0 7.7 25.1 1.5 8.4 5.5 10.4 36.7 5.8 12.1 3.9 8.0 153.2 11.0 7.9 6.7 6.7 60.8 5.0 6.0 40.2 10.6 11.2 13.4 1.3 24.9 2.2 3.2 12.3 16.8 5.7 13.9 4.1 2.9 6.5 77.9 5.3 7.9 3.6 1.9 2.4 7.0 3.1 4.0 2.9 4.5 4.8 3.0 22.3 7.7 5.6 3.0 13.1 16.7 0.0 9.5 11.4 65.8 39.9 19.1 19.0 29.8 9.0 11.7 26.2 9.7 MEGF11 "DKFZp434L121, KIAA1781" ENSG00000157890 "Multiple EGF like domains 11" A6BM72 15 65895079-66253747 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 23.0;fallopian tube: 7.8;kidney: 8.4;retina: 14.2" "Group enriched" "Detected in many" 9 "Early spermatids: 175.8;Horizontal cells: 126.2;Late spermatids: 177.8;Oligodendrocyte precursor cells: 460.4" "Group enriched" "Detected in some" 5 "endometrial cancer: 0.7;glioma: 2.3;renal cancer: 0.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 3.3;HEK 293: 2.7;RPTEC TERT1: 9.2;SCLC-21H: 7.2;U-698: 2.0" "Region enriched" "Detected in all" 4 "cerebellum: 35.0" "Region enriched" "Detected in all" 7 "cerebellum: 25.8" NA NA "Cluster 77: Retina - Visual perception" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 68: Oligodendrocytes - Mixed function" "unprognostic (2.97e-2)" "unprognostic (1.23e-1)" "unprognostic (7.95e-2)" "unprognostic (1.84e-2)" "unprognostic (9.02e-3)" "unprognostic (6.45e-3)" "unprognostic (1.51e-1)" "unprognostic (4.08e-2)" "unprognostic (2.92e-1)" "unprognostic (1.23e-1)" "unprognostic (6.79e-3)" "unprognostic (6.81e-3)" "unprognostic (5.71e-5)" "unprognostic (7.94e-2)" "unprognostic (9.78e-3)" "unprognostic (2.03e-1)" "unprognostic (4.89e-2)" 0.0 0.1 8.3 0.2 5.3 0.3 0.1 23.0 7.0 0.1 0.4 0.1 0.0 0.1 0.8 0.1 7.8 0.0 0.1 10.5 7.5 8.4 0.0 0.5 0.1 6.6 8.8 0.3 0.2 0.0 3.0 0.0 7.0 0.1 0.0 14.2 0.1 0.1 0.1 1.3 0.1 0.0 4.5 0.2 0.3 3.9 8.0 0.1 0.0 0.0 0.0 0.0 0.1 7.4 0.0 0.1 0.3 3.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.5 0.0 0.2 0.0 0.2 0.0 0.1 0.1 2.7 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.8 0.1 0.0 1.2 0.0 0.0 9.2 0.2 7.2 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.1 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 8.3 5.3 23.0 7.0 10.5 7.5 6.6 8.8 7.0 4.5 8.0 7.4 0.2 0.0 3.7 5.2 0.4 2.2 0.7 1.0 0.6 5.3 0.8 0.0 1.4 0.0 0.3 3.7 8.4 0.3 0.4 0.0 0.0 0.1 175.8 0.3 0.3 1.5 0.0 0.4 9.5 0.2 0.1 0.7 2.6 0.8 0.0 0.2 2.9 0.0 0.1 126.2 18.4 0.0 0.0 0.3 3.5 177.8 2.5 0.4 0.0 1.0 0.0 4.4 0.0 460.4 1.7 0.1 0.1 1.5 1.3 0.6 0.0 2.2 0.8 25.7 0.0 1.0 0.5 2.9 1.9 0.6 3.8 0.5 0.9 0.1 0.0 0.5 MELK KIAA0175 ENSG00000165304 "Maternal embryonic leucine zipper kinase" Q14680 9 36572862-36677683 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 10.0;lymphoid tissue: 21.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 16.1;Erythroid cells: 15.2;Extravillous trophoblasts: 44.1;Spermatocytes: 23.2;Spermatogonia: 21.3" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 4 "T-reg: 1.7" "Lineage enriched" "Detected in single" 4 "T-cells: 1.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA017214 Uncertain NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 12: Non-specific - Cell cycle regulation" "HPA017214: AB_1853798" "unprognostic (5.03e-2)" "unprognostic (9.57e-2)" "unprognostic (2.27e-2)" "unprognostic (3.42e-3)" "unprognostic (2.16e-1)" "unprognostic (1.23e-1)" "prognostic unfavorable (2.91e-7)" "prognostic unfavorable (3.99e-4)" "unprognostic (1.26e-2)" "unprognostic (1.60e-2)" "prognostic unfavorable (4.58e-4)" "unprognostic (4.69e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (8.86e-3)" "unprognostic (1.37e-1)" "unprognostic (2.40e-1)" "unprognostic (1.35e-1)" 0.9 0.5 0.0 5.7 0.0 10.0 1.4 0.0 0.1 1.3 0.0 6.8 5.2 1.0 0.0 7.9 0.3 0.6 0.2 0.0 0.0 0.3 0.7 0.9 10.0 0.0 0.1 0.2 0.3 0.1 0.0 5.3 0.1 0.3 8.5 0.0 1.2 0.1 0.0 3.4 4.4 2.4 0.0 2.0 3.2 9.2 0.3 21.0 0.3 0.1 11.7 1.7 2.3 0.0 123.4 62.1 81.6 48.5 11.1 18.8 47.1 88.8 62.2 121.5 148.2 47.8 47.3 40.9 27.8 43.8 106.5 41.0 71.7 55.5 133.1 112.3 28.6 32.0 69.1 48.1 4.3 50.2 39.0 6.9 9.8 93.9 53.0 15.6 62.2 61.9 41.7 63.2 100.9 40.9 63.1 23.4 65.1 55.1 47.9 57.4 54.9 25.8 37.7 40.7 55.1 40.8 47.4 45.3 28.6 45.2 38.0 23.7 30.8 65.4 81.8 56.1 82.3 12.3 47.9 60.7 41.2 36.8 91.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 1.7 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.7 1.9 4.6 0.9 3.5 0.0 0.0 0.9 0.8 0.4 0.0 2.0 0.0 0.0 16.1 0.7 4.5 0.0 1.1 2.8 2.9 1.4 1.3 0.0 15.2 0.8 1.1 44.1 3.3 4.6 2.1 0.0 7.8 1.4 0.7 10.1 0.0 0.7 4.7 4.1 1.6 3.0 2.7 1.2 1.9 0.0 0.0 3.1 0.0 2.1 1.0 0.4 1.7 2.7 0.0 10.2 0.5 0.6 0.1 2.0 0.0 0.0 0.0 3.7 23.2 21.3 9.3 1.7 8.9 2.7 0.7 8.9 2.3 MFSD4A "DKFZp761N1114, FLJ25004, FLJ34577, MFSD4, UNQ3064" ENSG00000174514 "Major facilitator superfamily domain containing 4A" Q8N468 1 205568885-205602918 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 66.7;stomach 1: 132.6" "Cell type enhanced" "Detected in some" "Adipocytes: 11.3;Collecting duct cells: 9.2;Distal tubular cells: 13.7;Endometrial ciliated cells: 9.9;Glandular and luminal cells: 40.5;Proximal tubular cells: 7.7" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 17 "amygdala: 11.4;basal ganglia: 8.4;cerebral cortex: 18.4;hippocampal formation: 14.1;white matter: 5.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 1.5;SCLC-21H: 1.6" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebral cortex: 59.8" HPA055407 Approved NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 44: Endometrium - Transcription" "HPA055407: " "unprognostic (7.15e-4)" "prognostic favorable (7.54e-4)" "unprognostic (5.60e-2)" "unprognostic (1.38e-1)" "unprognostic (2.09e-1)" "unprognostic (1.56e-2)" "unprognostic (1.25e-1)" "prognostic favorable (4.59e-4)" "unprognostic (2.73e-2)" "unprognostic (1.65e-2)" "unprognostic (3.20e-2)" "unprognostic (6.97e-3)" "prognostic favorable (2.27e-13)" "unprognostic (1.58e-1)" "unprognostic (4.44e-2)" "unprognostic (5.75e-3)" "unprognostic (8.78e-2)" 2.2 0.4 11.4 1.1 8.4 0.0 2.7 0.6 18.4 8.5 0.0 13.8 1.9 1.0 9.2 1.4 2.5 16.8 0.9 14.1 0.0 66.7 0.2 6.8 0.4 0.0 0.0 0.6 1.4 0.4 1.5 6.2 0.0 1.4 18.2 14.0 17.1 0.6 0.3 5.1 1.4 0.8 0.0 0.6 132.6 0.5 0.0 0.6 0.4 0.7 1.3 0.7 0.8 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.7 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 1.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 8.4 0.6 18.4 14.1 0.0 0.0 0.0 0.0 0.0 0.0 5.3 11.3 6.4 2.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 3.8 2.9 0.0 0.0 6.2 9.2 0.0 0.5 0.7 0.0 13.7 1.4 0.0 9.9 6.0 2.5 0.0 0.0 0.0 6.2 0.1 0.5 0.0 40.5 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 7.7 2.9 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.8 0.2 0.0 0.0 MKI67 "MIB-1, PPP1R105" ENSG00000148773 "Marker of proliferation Ki-67" P46013 10 128096659-128126423 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 46.3;lymphoid tissue: 52.7" "Cell type enhanced" "Detected in many" "Erythroid cells: 232.9;Extravillous trophoblasts: 86.1;Granulosa cells: 87.0;Plasma cells: 107.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "CAB000058, HPA000451, HPA001164, CAB068198" Enhanced Enhanced "Nucleoplasm,Nucleoli rim,Mitotic chromosome" Yes Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nucleoli rim" "Mitotic chromosome" "CAB000058: AB_2142367, CAB068198: AB_2665702, HPA000451: AB_1079186, HPA001164: AB_1079187" "unprognostic (2.54e-1)" "unprognostic (1.29e-1)" "unprognostic (3.37e-1)" "unprognostic (9.92e-3)" "unprognostic (3.17e-1)" "unprognostic (1.10e-1)" "prognostic unfavorable (3.61e-6)" "unprognostic (7.16e-3)" "unprognostic (1.45e-2)" "unprognostic (3.73e-1)" "prognostic unfavorable (9.47e-5)" "unprognostic (2.45e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.42e-2)" "unprognostic (2.10e-1)" "unprognostic (2.50e-1)" "unprognostic (4.61e-1)" 0.9 0.7 0.0 8.5 0.1 46.3 1.7 0.0 0.1 1.2 0.2 8.1 6.2 1.0 0.0 10.0 0.3 0.9 0.3 0.1 0.1 0.4 0.8 1.4 14.9 0.1 1.0 0.2 0.2 0.1 0.1 4.1 0.6 0.4 9.2 0.0 1.4 0.1 0.0 6.6 5.8 2.6 0.0 4.8 4.2 2.3 0.9 52.7 0.4 0.1 16.4 1.8 2.8 0.3 204.6 101.5 103.2 73.6 4.3 8.7 32.1 75.7 55.3 70.3 62.3 83.9 82.3 152.6 21.3 51.9 46.4 120.7 109.3 56.8 104.7 161.8 53.1 131.0 79.4 52.7 0.1 186.0 68.0 2.0 2.5 72.2 73.2 17.2 69.8 69.5 61.2 142.1 70.5 80.9 111.7 56.6 41.3 52.7 45.7 82.2 135.1 20.3 25.6 56.2 35.9 38.9 107.1 38.0 17.3 33.9 31.4 39.3 65.0 37.0 73.6 53.0 206.8 64.2 54.9 177.2 30.7 83.3 32.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 1.0 0.6 0.0 0.9 0.3 0.6 0.0 5.4 0.0 16.0 6.4 1.6 5.3 0.6 0.0 3.9 3.2 1.6 1.5 5.3 0.0 0.0 30.6 7.4 25.0 0.0 0.8 4.2 2.3 10.2 6.7 6.7 232.9 0.0 0.0 86.1 13.5 34.7 13.2 1.3 87.0 5.7 1.7 42.1 0.0 0.0 22.4 2.0 12.9 13.7 0.9 0.3 16.6 3.6 0.0 0.2 0.0 8.2 0.0 0.0 0.1 3.0 0.4 107.4 4.6 2.6 0.1 1.6 0.0 0.0 0.5 13.6 8.1 24.1 50.4 3.0 7.8 23.0 2.7 47.1 4.8 MMP25 "MMP20, MMPL1, MT6-MMP" ENSG00000008516 "Matrix metallopeptidase 25" Q9NPA2 16 3046062-3060726 "Enzymes, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 33.1;lymphoid tissue: 81.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 6.7;Langerhans cells: 5.8;monocytes: 15.0" "Cancer enriched" "Detected in many" 5 "testis cancer: 7.1" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 5 "basophil: 18.3;neutrophil: 20.3" "Lineage enriched" "Detected in single" 39 "granulocytes: 20.3" "Cell line enriched" "Detected in some" 15 "HMC-1: 102.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB025177, HPA055640" Uncertain Supported "Plasma membrane" "Secreted to blood" NA NA 120000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 3: Monocytes - Immune response regulation" "Plasma membrane" "CAB025177: , HPA055640: " "unprognostic (4.51e-3)" "unprognostic (9.28e-3)" "unprognostic (7.57e-2)" "unprognostic (2.95e-3)" "unprognostic (2.26e-1)" "prognostic favorable (1.09e-5)" "unprognostic (1.36e-1)" "unprognostic (7.39e-3)" "unprognostic (7.63e-3)" "unprognostic (2.29e-2)" "unprognostic (1.51e-1)" "unprognostic (2.53e-2)" "unprognostic (2.37e-3)" "unprognostic (1.17e-2)" "unprognostic (8.30e-2)" "unprognostic (4.01e-1)" "unprognostic (2.02e-1)" 5.8 0.4 0.5 15.1 0.4 33.1 1.4 0.3 1.6 0.7 0.6 1.7 1.1 0.5 0.1 1.3 6.2 1.1 2.4 0.3 0.3 1.4 2.9 14.4 2.6 0.6 0.5 0.4 1.2 0.2 0.8 1.0 0.6 1.0 1.4 0.0 1.2 0.1 0.5 0.7 3.5 0.9 0.3 81.8 1.9 0.4 0.7 1.4 1.2 3.5 1.9 2.2 0.9 0.3 0.0 0.0 1.2 2.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.7 0.7 0.1 0.0 6.7 0.5 0.0 0.0 0.0 0.0 0.2 102.2 0.1 0.1 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 5.7 2.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.2 0.3 7.0 0.3 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.1 1.1 0.1 18.3 0.2 4.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 20.3 0.5 0.0 0.4 0.2 0.0 0.5 0.4 0.3 1.6 0.3 0.3 0.6 0.5 0.6 0.3 0.7 0.3 1.0 3.2 6.7 0.0 0.7 0.4 0.4 0.2 0.0 0.8 2.0 1.3 1.0 0.0 0.8 1.8 0.0 0.0 1.8 0.2 0.0 0.4 0.0 1.2 1.2 1.0 0.0 2.7 1.6 0.6 0.2 0.6 1.1 3.8 1.3 0.2 0.0 0.3 0.1 0.0 1.9 0.2 0.0 3.5 5.8 0.0 0.0 3.3 0.0 1.0 15.0 0.3 3.1 1.5 0.5 1.3 0.0 0.7 0.8 0.4 1.2 0.2 0.1 0.0 0.0 0.7 0.9 0.1 0.2 0.6 0.3 0.0 4.0 0.1 0.3 0.3 MND1 GAJ ENSG00000121211 "Meiotic nuclear divisions 1" Q9BWT6 4 153344649-153415118 "Predicted intracellular proteins" "DNA recombination, Meiosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 13.3;lymphoid tissue: 26.7;testis: 15.9" "Cell type enhanced" "Detected in many" "Early spermatids: 25.9;Erythroid cells: 30.9;Spermatocytes: 55.5;Spermatogonia: 96.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 1.3;T-reg: 1.7" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA043499 Supported NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 24: NB-4 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" "HPA043499: AB_2732506" "unprognostic (2.21e-2)" "unprognostic (6.46e-3)" "unprognostic (9.79e-2)" "unprognostic (1.61e-1)" "unprognostic (7.98e-2)" "unprognostic (2.97e-1)" "prognostic unfavorable (2.72e-4)" "unprognostic (6.21e-3)" "prognostic unfavorable (3.40e-4)" "unprognostic (5.28e-2)" "unprognostic (1.28e-2)" "unprognostic (9.43e-2)" "unprognostic (2.71e-8)" "unprognostic (7.65e-2)" "unprognostic (5.70e-2)" "unprognostic (9.84e-2)" "unprognostic (7.64e-2)" 0.5 0.5 1.1 4.7 1.2 13.3 2.5 1.0 2.0 0.7 0.7 4.4 3.0 0.7 1.2 3.3 0.5 1.0 0.4 1.1 1.3 0.6 1.3 0.8 12.0 1.4 1.1 0.3 0.3 0.0 0.3 2.4 1.2 0.5 5.1 0.0 0.9 0.9 1.3 2.1 2.6 1.5 1.1 1.8 1.6 15.9 1.3 26.7 0.4 0.5 14.0 1.3 1.3 1.7 38.6 17.7 52.7 30.6 0.7 7.2 20.9 35.1 15.4 31.4 25.6 32.8 26.1 74.4 5.8 8.5 29.5 15.7 52.3 15.8 39.9 47.7 19.9 39.1 17.3 42.9 1.1 88.2 17.9 1.9 3.3 24.4 21.1 7.8 10.7 86.0 71.0 91.9 26.8 21.5 124.1 116.0 39.1 17.9 17.8 74.1 18.2 35.8 19.3 9.7 26.5 23.3 15.7 17.7 30.0 26.5 14.7 72.1 2.6 24.1 34.8 28.1 32.6 79.0 96.0 58.8 24.1 69.6 28.9 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.0 1.3 0.0 0.3 0.0 0.0 0.4 0.0 0.1 1.7 0.1 1.1 1.2 1.0 2.0 1.1 1.3 1.4 1.1 1.2 1.1 1.3 1.7 0.2 0.0 0.5 2.6 1.9 2.8 1.8 5.1 0.0 0.0 2.2 4.6 0.6 2.8 0.7 0.0 0.0 14.5 1.0 4.1 1.9 0.3 25.9 3.5 1.6 1.3 0.0 30.9 1.6 0.5 20.6 3.6 2.0 5.7 0.0 11.8 1.4 1.0 12.5 0.0 2.6 4.3 4.1 2.5 5.0 20.5 0.9 2.4 3.6 1.9 0.1 0.0 1.0 2.0 23.3 0.6 1.6 2.2 7.7 1.2 0.7 0.1 1.0 0.0 6.6 0.9 8.6 55.5 96.3 10.2 1.4 2.5 2.5 1.5 10.3 2.7 MS4A4A "CD20L1, MS4A4, MS4A7" ENSG00000110079 "Membrane spanning 4-domains A4A" Q96JQ5 11 60185657-60318080 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 63.1" "Group enriched" "Detected in many" 7 "Hofbauer cells: 376.8;Kupffer cells: 445.0;Macrophages: 264.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "intermediate monocyte: 61.2;myeloid DC: 27.6;non-classical monocyte: 82.9;plasmacytoid DC: 27.7" "Group enriched" "Detected in many" 30 "dendritic cells: 27.7;monocytes: 82.9" "Cell line enhanced" "Detected in some" "HEL: 35.6;HMC-1: 45.8;K-562: 154.9" HPA029323 Approved NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 1: K-562 - Erythropoiesis" "Cluster 4: Macrophages - Innate immune response" "HPA029323: AB_10601866" "unprognostic (7.93e-2)" "unprognostic (2.05e-2)" "unprognostic (1.37e-3)" "unprognostic (1.98e-1)" "unprognostic (4.46e-2)" "unprognostic (2.31e-1)" "unprognostic (9.66e-2)" "unprognostic (1.59e-1)" "unprognostic (4.56e-1)" "unprognostic (6.65e-2)" "unprognostic (8.10e-2)" "unprognostic (2.11e-1)" "unprognostic (5.02e-3)" "unprognostic (3.32e-2)" "unprognostic (4.66e-2)" "unprognostic (4.89e-2)" "unprognostic (4.21e-2)" 42.8 24.7 3.5 16.5 3.6 6.1 12.3 3.7 8.6 14.1 4.4 14.0 5.2 4.9 3.4 8.9 11.6 25.8 8.4 3.5 3.9 4.8 15.4 28.0 31.3 4.2 3.4 4.1 4.0 3.3 3.3 63.1 3.6 3.4 16.1 2.0 7.6 4.9 2.3 2.9 13.5 20.0 2.5 33.3 6.6 3.0 5.5 11.5 3.7 10.4 7.5 28.0 3.3 4.3 0.3 0.1 0.1 0.6 0.0 0.2 0.7 0.6 0.0 0.2 0.4 0.3 0.9 0.8 0.4 0.0 0.4 0.3 0.5 0.1 0.6 1.6 0.0 35.6 0.7 0.6 0.1 1.2 45.8 0.4 0.3 0.2 0.8 0.2 0.0 0.4 154.9 4.2 0.6 0.7 0.6 0.9 0.7 0.3 0.1 0.7 0.0 2.5 0.1 1.5 0.5 0.5 0.3 0.3 0.1 0.7 0.7 8.9 0.8 1.5 0.6 0.4 0.2 6.0 0.7 0.5 0.2 0.8 0.2 0.1 9.9 0.0 0.1 61.2 0.2 1.0 0.1 0.1 27.6 0.3 0.2 0.1 0.9 1.8 82.9 27.7 0.1 6.0 3.5 3.6 3.7 8.6 3.5 3.9 4.2 3.4 3.6 2.5 5.5 4.3 2.3 0.0 7.9 0.0 3.0 1.8 0.1 0.0 0.6 0.0 0.3 2.2 3.4 2.8 2.5 0.0 0.0 1.8 7.5 0.0 0.0 0.0 0.7 0.0 0.0 5.7 0.0 13.0 0.1 0.0 2.0 1.6 0.0 0.0 7.6 0.0 47.5 4.6 376.8 0.0 0.1 0.0 0.0 445.0 24.9 1.0 0.9 264.6 3.6 10.3 8.3 0.4 0.0 0.0 0.2 0.2 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.1 13.1 1.2 1.1 0.1 0.2 0.7 1.8 3.6 1.5 0.1 0.0 0.1 MS4A6A "CD20L3, MS4A6" ENSG00000110077 "Membrane spanning 4-domains A6A" Q9H2W1 11 60172014-60184666 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 580.8;Hofbauer cells: 376.8;Kupffer cells: 1649.6;Langerhans cells: 470.0;Macrophages: 675.9;monocytes: 429.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 8 "basophil: 406.4;classical monocyte: 1095.3;intermediate monocyte: 345.6;myeloid DC: 638.8;plasmacytoid DC: 454.4" "Group enriched" "Detected in all" 74 "dendritic cells: 638.8;granulocytes: 406.4;monocytes: 1095.3" "Cell line enriched" "Detected in some" 8 "THP-1: 47.9" "HPA011391, HPA076623" Approved Approved Vesicles NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA011391: AB_10603876, HPA076623: AB_2686809" "unprognostic (1.17e-1)" "prognostic favorable (6.33e-4)" "unprognostic (2.35e-2)" "unprognostic (1.21e-2)" "unprognostic (1.00e-1)" "unprognostic (8.51e-2)" "unprognostic (2.33e-1)" "unprognostic (3.75e-2)" "unprognostic (3.61e-1)" "unprognostic (1.76e-1)" "unprognostic (1.91e-1)" "unprognostic (3.20e-1)" "unprognostic (4.75e-3)" "unprognostic (1.06e-1)" "unprognostic (4.66e-2)" "unprognostic (3.94e-2)" "unprognostic (2.97e-2)" 72.6 42.3 10.7 57.5 10.9 33.5 40.0 10.8 22.5 28.1 14.7 41.0 27.8 14.3 9.6 25.7 16.8 61.4 22.8 10.0 11.8 11.5 108.6 56.4 109.1 15.8 13.7 12.3 7.8 8.7 9.8 65.2 14.8 12.4 54.9 1.4 16.0 18.3 5.3 7.3 45.1 52.6 12.4 121.5 24.5 7.8 13.6 32.2 10.0 17.7 47.6 59.9 8.6 17.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 1.3 0.2 0.0 0.0 0.0 0.0 0.0 4.1 0.0 5.7 0.0 0.0 0.0 0.0 4.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 47.9 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 4.1 0.0 406.4 1095.3 8.2 1.6 345.6 3.4 9.6 2.2 1.4 638.8 1.5 1.0 1.0 72.8 2.1 24.4 454.4 1.9 752.8 10.7 10.9 10.8 22.5 10.0 11.8 15.8 13.7 14.8 12.4 13.6 17.6 5.3 6.4 22.9 0.0 16.1 9.3 0.6 0.0 1.2 0.3 2.2 8.0 3.3 17.2 2.5 3.7 0.0 2.0 220.6 0.3 0.0 0.0 2.2 0.4 0.2 12.8 0.0 43.9 0.1 0.0 2.7 4.3 2.6 0.2 13.9 0.1 580.8 20.5 376.8 0.0 0.1 0.1 0.0 1649.6 470.0 5.1 1.5 675.9 14.2 40.3 429.2 0.0 11.3 0.5 0.1 0.0 1.2 0.0 2.0 0.2 0.0 0.5 1.5 0.6 46.0 3.0 4.4 0.5 1.1 2.4 8.0 2.1 10.4 0.1 0.2 0.3 MS4A7 "CD20L4, CFFM4, MS4A8" ENSG00000166927 "Membrane spanning 4-domains A7" Q9GZW8 11 60378485-60395951 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 196.6" "Cell type enhanced" "Detected in many" "Hofbauer cells: 311.4;Kupffer cells: 1060.3;Macrophages: 567.5;monocytes: 184.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "intermediate monocyte: 747.4;non-classical monocyte: 1486.0" "Lineage enriched" "Detected in many" 12 "monocytes: 1486.0" "Cell line enriched" "Detected in some" 25 "THP-1: 114.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA017418, CAB026387" Approved NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "CAB026387: , HPA017418: AB_1854137" "unprognostic (1.43e-1)" "unprognostic (2.60e-3)" "unprognostic (3.24e-2)" "unprognostic (9.67e-2)" "unprognostic (2.04e-1)" "unprognostic (1.81e-1)" "unprognostic (1.04e-1)" "unprognostic (9.51e-2)" "unprognostic (3.02e-2)" "unprognostic (4.85e-2)" "unprognostic (5.79e-2)" "unprognostic (1.90e-1)" "unprognostic (1.43e-2)" "unprognostic (4.59e-2)" "unprognostic (3.90e-2)" "unprognostic (1.18e-1)" "unprognostic (1.03e-1)" 46.9 37.6 6.3 50.9 5.0 10.7 30.7 4.5 13.7 18.2 13.9 21.4 17.6 7.6 4.1 12.7 6.6 46.8 9.9 4.2 8.7 8.0 66.5 75.7 23.2 12.8 10.4 6.0 6.0 9.0 4.7 43.9 11.4 4.9 23.3 1.2 6.7 9.0 1.9 2.3 25.1 15.9 7.4 196.6 14.8 4.7 17.1 18.2 7.3 4.1 18.6 41.2 3.9 18.3 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 2.5 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 4.5 0.1 0.0 0.1 1.1 0.1 0.1 0.0 2.8 0.0 0.1 0.1 0.8 0.5 0.0 0.0 114.2 0.0 0.1 0.1 0.1 0.1 0.2 0.2 3.0 0.0 3.1 0.0 8.3 188.0 2.5 0.8 747.4 1.1 22.3 0.6 0.5 120.9 19.7 0.8 0.4 9.3 0.8 1486.0 3.2 0.9 137.8 6.3 5.0 4.5 13.7 4.2 8.7 12.8 10.4 11.4 7.4 17.1 18.3 5.0 12.8 31.4 0.0 30.6 2.7 0.8 0.0 0.6 3.6 14.7 9.9 2.1 0.0 3.7 9.2 0.0 1.0 1.4 0.3 0.0 0.0 2.4 0.1 0.0 12.2 0.0 10.1 0.1 0.2 1.7 3.9 1.5 0.1 13.9 0.1 11.0 4.7 311.4 0.0 0.2 0.0 0.0 1060.3 93.4 1.2 1.2 567.5 1.8 59.0 184.8 0.4 4.1 0.0 0.3 0.1 1.1 0.0 1.8 1.1 0.0 0.7 7.3 0.5 19.7 2.2 1.2 0.0 0.4 0.9 1.8 1.9 5.3 0.3 0.1 1.0 MS4A8 "CD20L5, MS4A4, MS4A8B" ENSG00000166959 "Membrane spanning 4-domains A8" Q9BY19 11 60699585-60715807 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "fallopian tube: 129.7;intestine: 197.7" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 376.4;Enteroendocrine cells: 473.4;Ionocytes: 140.4;Proximal enterocytes: 694.6;Respiratory ciliated cells: 502.8" "Cancer enhanced" "Detected in many" "endometrial cancer: 14.1" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "OE19: 1.9;RPMI-8226: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA007319 Enhanced NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" "HPA007319: AB_1854138" "unprognostic (7.28e-3)" "unprognostic (2.11e-1)" "unprognostic (9.03e-2)" "unprognostic (1.91e-2)" "unprognostic (2.52e-2)" "unprognostic (9.41e-2)" "unprognostic (4.89e-3)" "unprognostic (9.33e-2)" "unprognostic (7.97e-3)" "unprognostic (2.40e-1)" "unprognostic (2.40e-9)" "unprognostic (2.46e-1)" "unprognostic (3.02e-2)" "unprognostic (1.59e-3)" 0.0 0.8 1.6 3.5 1.3 0.0 0.0 0.0 1.1 25.6 5.4 18.2 189.8 8.2 0.0 0.3 129.7 10.8 0.0 0.6 0.4 0.1 0.0 16.6 0.2 0.0 0.2 0.3 2.2 0.7 7.5 0.1 0.0 1.7 16.9 0.0 0.6 7.1 4.6 0.0 197.7 1.0 0.0 0.0 45.7 0.5 0.9 0.1 0.0 0.0 1.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 1.9 0.0 0.0 0.0 1.4 0.0 0.0 0.8 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.3 0.0 1.1 0.6 0.4 0.0 0.2 0.0 0.0 0.9 0.0 0.0 6.4 6.4 0.0 0.2 0.0 0.2 11.9 0.0 0.0 0.0 0.0 0.3 18.6 58.8 1.8 0.0 0.0 0.0 15.0 0.0 0.3 1.3 376.4 3.2 0.3 473.4 0.0 0.4 2.5 0.0 2.0 14.3 11.6 1.3 0.0 0.0 0.0 0.0 0.0 0.1 42.5 140.4 0.0 0.0 1.3 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 46.1 0.0 0.0 1.7 694.6 0.2 502.8 0.0 0.0 0.0 3.5 0.3 0.7 0.0 0.0 0.0 0.5 0.2 24.7 0.4 MTFR2 "DUFD1, FAM54A" ENSG00000146410 "Mitochondrial fission regulator 2" Q6P444 6 136231024-136250335 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 16.3;lymphoid tissue: 6.4;testis: 7.0" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 23.6;Spermatocytes: 27.6;Spermatogonia: 13.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA029792, HPA029794" Approved Uncertain Vesicles NA Yes "Cluster 28: Myeloid DCs - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: U-937 - Innate immune response" "Cluster 12: Non-specific - Cell cycle regulation" Vesicles "HPA029792: AB_10600210, HPA029794: AB_10600535" "unprognostic (6.49e-3)" "unprognostic (6.29e-2)" "unprognostic (1.65e-1)" "prognostic unfavorable (9.64e-4)" "unprognostic (3.93e-1)" "unprognostic (1.75e-2)" "unprognostic (4.60e-6)" "prognostic unfavorable (8.28e-4)" "unprognostic (3.77e-2)" "unprognostic (1.22e-1)" "unprognostic (6.27e-2)" "unprognostic (6.54e-2)" "unprognostic (1.11e-16)" "unprognostic (8.82e-3)" "unprognostic (1.55e-1)" "unprognostic (4.10e-2)" "unprognostic (3.64e-2)" 0.8 0.5 0.4 3.6 0.3 16.3 1.0 0.4 0.6 0.6 0.2 2.9 2.8 0.5 0.3 2.6 0.3 0.3 0.3 0.4 0.3 0.6 0.4 1.2 6.4 0.4 0.5 0.3 0.4 0.0 0.4 1.8 0.3 0.4 3.8 0.5 0.8 0.2 1.2 1.9 2.3 1.1 0.4 2.2 1.2 7.0 0.4 6.2 0.3 0.1 5.3 0.8 0.9 0.4 15.2 11.5 9.7 18.2 1.6 2.8 17.4 19.6 13.6 22.8 31.7 20.7 12.2 39.2 11.7 7.9 30.1 23.1 22.3 14.4 33.8 22.1 17.1 31.0 7.8 18.9 1.0 57.4 28.1 2.3 3.1 25.5 16.1 2.7 12.4 33.8 33.9 29.6 17.2 20.2 32.5 47.8 9.8 20.2 14.1 29.3 15.5 19.7 9.9 11.6 7.7 7.6 12.4 21.5 11.3 11.9 9.1 39.1 6.8 11.3 11.8 40.2 30.4 11.2 28.3 26.1 6.5 38.5 17.6 0.0 0.2 0.0 0.3 0.9 0.1 0.4 0.4 0.7 0.9 0.3 0.0 0.4 0.0 0.0 0.7 0.7 0.7 0.3 0.4 0.3 0.4 0.6 0.4 0.3 0.4 0.5 0.3 0.4 0.4 0.4 2.0 0.0 1.1 0.0 2.2 1.0 0.6 3.1 0.0 0.0 3.4 3.6 0.4 0.0 2.3 0.0 0.0 8.4 1.3 2.2 0.0 1.1 7.9 2.4 1.3 1.7 0.0 9.9 0.5 2.5 23.6 1.5 2.6 2.5 1.3 3.5 0.7 0.5 6.6 0.0 0.4 2.1 4.1 3.8 2.1 5.9 0.3 2.5 0.0 1.0 2.3 0.0 1.0 0.5 0.0 1.3 0.4 0.0 7.4 1.2 1.3 1.4 2.5 0.0 0.0 5.3 1.8 27.6 13.0 5.3 0.3 3.0 3.1 0.8 4.6 0.9 MUC13 DRCC1 ENSG00000173702 "Mucin 13, cell surface associated" Q9H3R2 3 124905442-124953819 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "intestine: 614.6" "Cell type enhanced" "Detected in some" "Distal enterocytes: 853.2;Intestinal goblet cells: 418.5;Paneth cells: 641.9;Proximal enterocytes: 422.5;Undifferentiated cells: 207.9" "Cancer enhanced" "Detected in many" "colorectal cancer: 198.4;stomach cancer: 152.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 16 "OE19: 220.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045163, HPA079663" Enhanced "Secreted to digestive system" NA NA "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA045163: AB_10960396, HPA079663: " "unprognostic (8.42e-2)" "unprognostic (1.34e-1)" "unprognostic (1.77e-1)" "unprognostic (1.55e-3)" "unprognostic (2.93e-1)" "unprognostic (2.11e-2)" "unprognostic (1.26e-1)" "unprognostic (3.48e-2)" "unprognostic (2.94e-1)" "unprognostic (5.10e-2)" "unprognostic (2.02e-1)" "unprognostic (9.64e-2)" "prognostic unfavorable (9.73e-5)" "unprognostic (2.05e-3)" "unprognostic (1.10e-1)" "unprognostic (2.29e-1)" "unprognostic (1.42e-1)" 0.8 0.8 0.0 62.0 0.0 0.1 0.5 0.0 0.1 0.8 0.0 304.6 614.6 1.5 0.0 0.8 2.8 47.9 0.1 0.0 0.0 17.5 3.7 0.3 0.4 0.2 0.0 0.0 4.5 0.0 0.1 0.0 0.3 2.1 301.3 0.0 0.0 0.8 0.0 0.1 503.8 10.9 0.0 0.1 35.3 0.3 0.0 0.0 0.0 0.1 0.1 0.8 0.1 0.0 0.0 7.4 0.0 0.0 0.0 0.0 1.1 0.9 0.0 0.0 0.1 6.4 13.6 0.0 0.8 0.2 0.1 1.0 0.0 0.0 0.0 0.1 0.1 0.0 1.5 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 7.9 0.1 0.0 0.0 1.0 0.0 220.9 1.1 0.0 0.1 2.7 0.0 0.0 0.3 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.1 0.1 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.3 3.0 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.3 25.8 0.8 0.0 0.0 0.0 0.0 853.2 0.0 24.7 0.9 120.0 1.5 0.4 153.8 0.0 0.1 31.4 0.0 0.0 36.7 6.1 8.9 0.0 0.0 0.0 0.0 0.0 0.2 418.5 0.0 0.3 0.0 4.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 15.8 641.9 0.7 0.0 1.5 422.5 7.7 10.1 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 1.5 0.0 207.9 1.4 MUC5AC MUC5 ENSG00000215182 "Mucin 5AC, oligomeric mucus/gel-forming" P98088 11 1157953-1201138 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 101 "stomach 1: 185.1" "Cell type enriched" "Detected in some" 248 "Gastric mucus-secreting cells: 10434.9" "Group enriched" "Detected in many" 4 "pancreatic cancer: 25.3;stomach cancer: 61.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 16 "A549: 19.9;OE19: 13.5" "Not detected" "Not detected" "Not detected" "Not detected" "CAB002774, CAB009395, HPA040615" Enhanced "Secreted to digestive system" NA NA "Cluster 4: Stomach - Digestion" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" "CAB002774: , CAB009395: AB_2146854, HPA040615: AB_2677042" "unprognostic (2.10e-2)" "unprognostic (1.11e-1)" "unprognostic (1.27e-1)" "unprognostic (3.14e-2)" "unprognostic (1.72e-2)" "unprognostic (2.51e-2)" "unprognostic (4.56e-2)" "unprognostic (6.49e-2)" "unprognostic (2.44e-2)" "unprognostic (1.30e-3)" "unprognostic (8.46e-2)" "unprognostic (5.83e-4)" "unprognostic (1.84e-1)" "unprognostic (9.21e-3)" "unprognostic (4.07e-1)" "unprognostic (1.37e-1)" 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.2 0.0 0.0 0.0 0.4 0.0 1.4 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 185.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 19.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 13.5 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 17.4 0.0 0.1 5.4 0.0 0.0 0.1 0.0 2.7 0.0 42.0 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.8 0.0 2.8 10434.9 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.8 4.1 0.0 0.0 0.2 0.0 14.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.1 0.0 30.0 8.9 0.0 0.0 10.0 0.0 0.0 0.0 1.3 0.0 0.4 0.0 0.0 0.1 7.9 0.0 0.0 28.1 MUCL3 "bCX105N19.6, C6orf37, DPCR1, PBLT" ENSG00000168631 "Mucin like 3" Q3MIW9 6 30934523-30954221 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "stomach 1: 202.8" "Cell type enriched" "Detected in some" 20 "Pancreatic endocrine cells: 239.5" "Group enriched" "Detected in some" 9 "pancreatic cancer: 56.8;stomach cancer: 55.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "OE19: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA014036 Enhanced NA NA "Cluster 4: Stomach - Digestion" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA014036: AB_1847841" "unprognostic (2.81e-1)" "unprognostic (4.49e-2)" "unprognostic (9.13e-4)" "unprognostic (6.74e-2)" "unprognostic (4.29e-2)" "unprognostic (8.06e-2)" "unprognostic (3.08e-1)" "unprognostic (1.03e-1)" "unprognostic (3.32e-3)" "unprognostic (2.79e-1)" "prognostic unfavorable (6.58e-4)" "unprognostic (1.13e-1)" "unprognostic (5.97e-2)" "unprognostic (4.76e-2)" "unprognostic (9.80e-2)" "unprognostic (3.20e-2)" "unprognostic (3.58e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 10.5 0.0 9.9 0.0 0.0 0.0 0.0 0.2 3.6 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 202.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 11.6 0.0 0.2 0.1 0.0 0.0 0.0 0.0 6.6 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 239.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 MYEOV OCIM ENSG00000172927 "Myeloma overexpressed" Q96EZ4 11 69294151-69367726 "Predicted membrane proteins" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 5.4;breast: 5.3;esophagus: 9.6;stomach 1: 6.0" "Cell type enriched" "Detected in many" 5 "Pancreatic endocrine cells: 199.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 172.8;A549: 83.5;CAPAN-2: 24.3;U-2 OS: 36.1" HPA012949 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" Nucleoplasm Vesicles "HPA012949: AB_1854241" "unprognostic (1.42e-2)" "unprognostic (8.56e-2)" "unprognostic (7.07e-2)" "unprognostic (3.36e-1)" "unprognostic (5.60e-2)" "unprognostic (7.28e-3)" "unprognostic (7.58e-3)" "prognostic unfavorable (2.00e-4)" "unprognostic (3.49e-1)" "unprognostic (6.33e-2)" "prognostic unfavorable (1.54e-7)" "unprognostic (2.83e-1)" "prognostic unfavorable (1.48e-5)" "unprognostic (2.08e-1)" "unprognostic (1.16e-1)" "unprognostic (3.35e-1)" "unprognostic (3.69e-2)" 5.4 0.1 0.0 0.6 0.0 0.1 5.3 0.0 0.0 1.8 0.0 0.5 0.3 0.0 0.7 9.6 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.1 0.1 0.1 0.0 0.0 1.8 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.6 0.0 0.0 4.1 0.2 0.0 0.0 0.2 6.0 0.0 0.0 0.0 0.1 0.0 1.0 0.1 3.9 0.0 172.8 83.5 0.0 0.0 0.0 0.0 2.5 0.2 0.1 0.0 0.0 0.5 24.3 0.5 6.3 0.0 0.1 2.5 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.4 0.0 0.0 6.4 0.0 0.0 0.1 0.0 0.1 8.5 0.0 2.4 0.2 0.1 3.8 0.1 0.1 0.2 3.4 6.8 0.0 0.1 3.5 0.6 0.2 0.0 0.0 0.0 2.4 0.6 0.0 2.9 0.7 1.6 0.1 36.1 0.0 1.4 0.3 1.7 0.2 0.2 0.5 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 1.0 0.8 0.8 3.8 0.0 0.0 30.7 37.7 0.4 0.0 17.6 3.7 0.0 0.0 0.9 7.8 0.0 12.6 12.7 1.2 0.1 0.5 0.0 0.0 0.0 9.4 0.4 3.4 23.9 1.5 0.0 0.1 0.0 0.2 2.4 0.0 0.0 1.3 2.0 0.0 0.0 6.9 0.3 4.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 199.3 22.3 0.0 3.9 1.4 0.0 0.0 1.5 0.0 0.0 0.1 2.9 0.0 0.4 3.4 1.3 0.1 0.4 0.0 2.7 8.5 NEIL3 "FLJ10858, FPG2, hFPG2, hNEI3, ZGRF3" ENSG00000109674 "Nei like DNA glycosylase 3" Q8TAT5 4 177309874-177362936 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Glycosidase, Hydrolase, Lyase, Multifunctional enzyme" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "bone marrow: 6.6;lymphoid tissue: 23.6" "Cell type enhanced" "Detected in some" "Erythroid cells: 14.7;Granulosa cells: 4.8;Plasma cells: 6.1;Squamous epithelial cells: 4.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HDLM-2: 72.1;HL-60: 79.1;Karpas-707: 99.1;MOLT-4: 80.7" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebellum: 3.3" HPA065761 Enhanced Nucleoplasm NA Yes "Cluster 48: NK-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA065761: AB_2685555" "unprognostic (6.03e-2)" "unprognostic (5.79e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (5.45e-4)" "unprognostic (4.91e-2)" "unprognostic (2.05e-1)" "unprognostic (3.64e-7)" "prognostic unfavorable (1.16e-4)" "unprognostic (6.09e-3)" "unprognostic (7.67e-2)" "unprognostic (6.51e-4)" "unprognostic (2.82e-3)" "unprognostic (0.00e+0)" "unprognostic (3.25e-2)" "unprognostic (8.13e-2)" "unprognostic (2.03e-1)" "unprognostic (1.04e-2)" 0.1 0.0 0.0 1.7 0.0 6.6 0.3 0.0 0.1 0.2 0.0 1.1 1.1 0.1 0.0 1.6 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 3.6 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 1.5 0.0 0.2 0.0 0.0 2.3 1.3 0.5 0.0 0.4 0.6 1.5 0.1 23.6 0.0 0.0 3.5 0.4 0.4 0.0 19.3 15.8 16.4 8.2 1.8 3.3 8.0 23.4 8.6 25.3 14.9 5.8 16.5 21.2 3.4 6.2 25.1 8.8 17.4 9.3 36.6 72.1 11.4 14.7 11.9 15.2 0.5 79.1 9.7 0.3 0.5 26.2 5.6 5.2 9.9 53.9 15.3 99.1 16.7 8.4 80.7 30.2 7.5 5.7 11.5 16.2 11.2 6.8 6.8 2.6 12.8 8.9 11.7 13.4 6.3 7.2 10.9 20.4 4.7 15.2 11.8 7.8 24.0 6.8 4.8 33.5 10.1 27.8 24.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.2 0.1 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.9 0.1 0.4 1.2 0.0 0.2 0.1 0.4 0.0 1.3 0.0 0.0 2.6 1.6 0.5 0.0 0.0 0.1 0.1 0.6 0.3 0.0 14.7 0.1 0.2 3.3 0.9 0.0 0.5 0.0 4.8 0.4 0.0 1.5 0.0 0.1 1.0 0.0 1.3 0.4 0.2 0.0 1.7 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.1 0.7 6.1 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.5 2.7 2.4 4.5 1.3 0.3 1.0 0.5 1.2 0.2 NEK2 "NEK2A, NLK1, PPP1R111, RP67" ENSG00000117650 "NIMA related kinase 2" P51955 1 211658657-211675630 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Meiosis, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 17.9;lymphoid tissue: 19.2;testis: 67.1" "Group enriched" "Detected in many" 4 "Early spermatids: 76.1;Spermatocytes: 244.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 5.7" "Low region specificity" "Detected in all" "CAB017530, HPA064967" Enhanced Supported Nucleoplasm,Centrosome NA Yes "Cluster 41: Basophils - Cellular respiration" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Centrosome" "CAB017530: AB_1126558, HPA064967: AB_2685393" "unprognostic (1.28e-1)" "unprognostic (2.33e-1)" "unprognostic (1.02e-1)" "unprognostic (8.51e-2)" "unprognostic (1.83e-1)" "unprognostic (1.35e-2)" "prognostic unfavorable (9.47e-6)" "prognostic unfavorable (9.11e-4)" "unprognostic (1.95e-2)" "unprognostic (2.00e-2)" "unprognostic (1.09e-3)" "unprognostic (8.49e-2)" "unprognostic (0.00e+0)" "unprognostic (8.21e-2)" "unprognostic (4.11e-2)" "unprognostic (1.25e-2)" "unprognostic (2.71e-1)" 0.7 0.4 0.5 5.3 0.4 17.9 1.5 0.9 0.6 1.1 0.6 5.9 7.4 1.3 0.5 4.4 2.2 0.8 0.4 0.5 0.3 0.3 0.7 0.7 9.0 0.4 0.2 0.4 0.1 0.1 0.0 3.2 0.3 2.5 7.6 1.5 0.8 0.2 0.4 4.3 6.9 2.0 0.2 1.7 2.7 67.1 0.6 19.2 0.4 0.2 10.6 1.3 1.6 0.9 86.0 60.5 45.3 32.6 2.6 4.5 49.7 32.4 30.1 55.4 47.5 32.3 81.7 45.1 15.2 25.2 35.1 44.5 39.9 24.2 69.6 69.5 33.2 21.6 51.4 44.2 0.4 43.2 28.3 1.4 2.9 42.9 45.9 13.4 36.3 45.2 59.9 76.9 56.0 23.6 47.3 28.8 43.0 55.0 30.5 46.2 69.2 68.7 19.7 24.2 41.0 45.0 46.6 51.5 39.3 38.4 79.4 25.1 19.0 27.6 54.1 54.8 88.3 31.6 62.6 59.6 24.1 32.6 46.8 1.2 0.1 0.1 0.1 0.1 0.0 0.5 0.1 0.1 0.0 0.4 0.3 0.2 0.7 1.5 0.1 0.2 1.6 0.3 0.5 0.4 0.9 0.6 0.5 0.3 0.4 0.2 0.3 0.2 0.6 0.9 0.1 0.0 0.5 0.3 1.7 2.9 0.7 3.8 0.6 11.3 1.9 2.2 0.5 0.0 2.9 0.0 0.0 9.4 0.8 1.9 0.0 0.2 76.1 15.2 0.7 0.8 0.0 39.6 0.8 0.2 14.1 1.4 5.6 1.5 0.0 3.6 3.6 0.7 5.8 3.3 0.0 3.2 10.2 2.5 1.1 39.0 2.5 2.1 0.0 0.0 0.0 1.6 2.1 0.0 0.1 0.0 2.5 0.7 5.4 0.7 2.1 0.1 5.2 1.8 6.6 0.0 1.5 244.2 26.1 8.6 1.7 1.4 2.0 0.9 9.5 1.4 NFE2 NF-E2 ENSG00000123405 "Nuclear factor, erythroid 2" Q16621 12 54292111-54301015 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 112.5;lymphoid tissue: 45.3" "Cell type enriched" "Detected in some" 5 "Erythroid cells: 265.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 5 "basophil: 1489.2;neutrophil: 810.6" "Lineage enriched" "Detected in many" 6 "granulocytes: 1489.2" "Group enriched" "Detected in some" 5 "HEL: 376.9;K-562: 168.1;NB-4: 118.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA001914 Enhanced Approved "Nucleoplasm,Actin filaments" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 36: HEL - Hemostasis" "Cluster 6: Erythroid cells - Oxygen transport" "Nucleoplasm, Actin filaments" "HPA001914: AB_1079475" "unprognostic (2.68e-4)" "unprognostic (2.93e-2)" "unprognostic (2.20e-2)" "unprognostic (2.31e-2)" "unprognostic (2.33e-2)" "unprognostic (1.85e-1)" "unprognostic (1.20e-2)" "unprognostic (4.55e-2)" "unprognostic (4.12e-1)" "unprognostic (4.55e-2)" "unprognostic (3.47e-2)" "unprognostic (2.57e-3)" "unprognostic (9.90e-6)" "unprognostic (1.81e-2)" "unprognostic (8.99e-2)" "unprognostic (1.51e-2)" "unprognostic (3.46e-2)" 3.8 0.3 0.5 6.2 0.7 112.5 0.6 0.5 1.0 1.4 1.4 0.4 0.5 0.3 0.1 0.8 2.4 1.2 1.9 0.5 0.5 1.4 2.6 13.0 0.3 0.7 0.6 0.2 0.7 1.1 0.9 4.0 0.7 0.5 0.2 0.0 0.5 0.1 1.3 4.8 0.6 1.9 0.5 45.3 0.8 1.2 0.6 1.4 1.4 3.7 0.1 2.3 0.5 0.6 0.3 0.3 0.0 0.0 0.0 0.5 1.4 1.1 6.9 0.7 0.9 5.5 10.0 0.1 0.9 0.9 0.4 0.3 0.0 0.0 0.3 0.0 0.1 376.9 0.9 9.1 0.0 5.8 48.5 0.5 0.1 0.3 0.2 4.4 0.0 0.1 168.1 0.1 0.0 0.1 15.3 118.8 0.1 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 2.6 0.2 0.6 1.8 1.0 18.9 0.3 0.2 0.4 1.1 0.1 0.0 0.0 0.1 0.4 23.4 0.0 1489.2 241.7 232.3 0.6 66.7 1.0 0.3 0.8 0.5 156.7 0.5 1.0 0.7 810.6 1.1 42.0 2.7 0.2 160.2 0.5 0.7 0.5 1.0 0.5 0.5 0.7 0.6 0.7 0.5 0.6 0.6 0.0 0.0 3.0 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.1 1.5 0.1 0.0 0.0 0.2 1.3 0.0 0.0 0.1 5.9 0.1 0.0 0.0 0.0 265.6 0.0 0.0 0.5 0.4 0.0 0.1 3.8 0.1 0.4 0.2 1.0 0.0 0.0 0.0 0.0 22.8 0.2 19.0 0.0 44.3 1.8 0.0 33.9 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.1 0.8 0.0 0.0 0.1 0.0 0.3 1.3 0.0 0.3 1.2 1.1 0.0 0.1 0.1 OIP5 "CT86, hMIS18beta, MIS18B" ENSG00000104147 "Opa interacting protein 5" O43482 15 41309273-41332591 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 10.3;skeletal muscle: 10.3;testis: 20.9" "Cell type enhanced" "Detected in many" "Erythroid cells: 45.9;Extravillous trophoblasts: 24.0;Spermatocytes: 110.6;Spermatogonia: 56.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA052271, HPA059602" Enhanced Supported "Nuclear speckles,Vesicles" NA Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear speckles" Vesicles "HPA052271: AB_2681780, HPA059602: AB_2684079" "unprognostic (5.17e-2)" "unprognostic (7.26e-2)" "unprognostic (3.07e-1)" "unprognostic (1.59e-2)" "unprognostic (6.94e-2)" "unprognostic (6.58e-2)" "prognostic unfavorable (1.79e-4)" "prognostic unfavorable (2.26e-4)" "unprognostic (2.71e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (9.34e-5)" "unprognostic (5.51e-2)" "unprognostic (0.00e+0)" "unprognostic (3.84e-2)" "unprognostic (2.02e-1)" "unprognostic (5.75e-2)" "unprognostic (2.86e-2)" 0.6 1.7 0.1 3.3 0.2 10.3 1.2 1.2 0.4 0.9 0.2 4.1 3.5 0.8 0.3 3.8 0.4 0.6 1.5 0.2 0.2 0.3 1.2 0.5 5.8 0.2 0.4 1.5 0.3 0.1 0.1 2.3 0.4 0.5 3.9 0.7 0.8 0.6 10.3 3.3 3.9 1.1 0.1 1.7 1.5 20.9 0.2 9.1 0.4 0.8 5.2 0.7 1.3 0.5 33.7 17.8 34.3 24.9 1.7 2.1 32.4 20.0 9.3 24.5 26.1 31.8 16.2 19.8 17.0 7.7 37.8 51.0 35.7 16.1 19.2 42.4 40.1 42.4 49.8 33.6 0.4 46.5 22.1 0.7 3.2 13.8 14.5 5.2 21.1 40.8 59.4 37.3 16.5 16.3 27.1 34.8 30.9 50.4 37.9 32.9 28.4 30.5 11.1 15.4 53.7 17.5 33.7 34.3 9.6 13.7 33.7 26.3 10.0 24.5 37.3 24.6 36.6 17.0 83.2 71.1 7.1 56.5 35.9 0.0 0.4 0.5 0.2 0.7 0.8 1.0 0.7 0.8 0.7 1.2 1.3 0.8 0.0 1.2 0.4 4.1 3.1 0.8 0.1 0.2 1.2 0.4 0.2 0.2 0.2 0.4 0.4 0.1 0.2 0.5 0.2 0.0 0.5 1.0 2.7 4.1 0.9 3.6 1.2 0.0 1.1 2.2 0.2 0.0 1.8 0.0 0.0 15.0 1.7 2.3 0.0 0.4 12.0 1.9 0.6 0.9 0.0 45.9 2.2 0.4 24.0 1.7 5.1 1.1 1.3 5.2 0.0 0.8 7.5 0.0 2.1 3.0 8.2 2.2 1.8 10.8 0.9 1.2 0.0 0.0 0.6 1.1 2.1 1.5 2.5 0.2 0.5 1.2 10.9 0.4 0.9 0.3 0.0 0.3 6.6 1.0 1.1 110.6 56.8 8.3 2.4 3.8 1.2 2.1 7.6 0.9 ORC6 ORC6L ENSG00000091651 "Origin recognition complex subunit 6" Q9Y5N6 16 46689643-46698394 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA replication" DNA-binding "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 10.3;lymphoid tissue: 7.4;testis: 9.6" "Cell type enhanced" "Detected in many" "Granulosa cells: 56.7;Spermatocytes: 102.6;Spermatogonia: 108.9;Theca cells: 47.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016330, HPA072587" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center" Yes No "Cluster 24: B-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nucleoli fibrillar center" "CAB016330: AB_670295, HPA072587: AB_2686537" "unprognostic (3.47e-2)" "unprognostic (8.99e-3)" "unprognostic (2.92e-1)" "unprognostic (4.47e-2)" "unprognostic (2.27e-1)" "unprognostic (2.19e-2)" "unprognostic (3.15e-6)" "unprognostic (1.36e-2)" "prognostic unfavorable (3.53e-4)" "prognostic favorable (1.48e-4)" "unprognostic (1.50e-4)" "unprognostic (3.97e-2)" "unprognostic (3.90e-14)" "unprognostic (2.08e-1)" "unprognostic (4.24e-1)" "unprognostic (2.79e-1)" "unprognostic (5.98e-2)" 0.3 0.7 2.0 2.2 1.6 10.3 0.6 1.5 1.9 0.7 1.0 1.7 1.5 0.8 1.1 4.1 0.4 0.6 1.5 1.9 1.8 0.4 0.9 0.6 7.4 1.5 1.9 0.4 0.3 0.7 0.6 3.3 1.7 0.3 1.9 0.3 0.7 0.2 0.1 1.1 1.5 1.0 1.6 2.4 0.8 9.6 1.8 6.2 0.5 0.3 7.3 1.2 1.3 1.8 28.6 27.4 43.7 33.9 5.4 6.8 31.6 54.2 20.2 59.3 30.9 39.3 18.0 35.6 27.1 10.5 29.1 29.9 57.9 15.1 50.4 17.2 46.4 27.9 13.2 40.1 6.6 46.5 23.7 1.8 2.6 32.4 17.1 9.3 20.0 30.1 36.0 17.4 35.9 26.9 65.6 60.7 48.1 20.7 76.0 78.6 80.6 35.8 14.9 9.8 52.2 30.4 24.5 29.8 18.1 34.9 15.6 37.9 11.6 53.7 34.6 33.6 51.8 12.5 18.9 123.2 22.2 29.5 40.1 0.0 0.3 0.3 0.9 0.7 0.4 0.7 0.5 0.5 0.6 1.4 0.8 0.3 0.0 0.8 0.8 1.0 1.2 0.7 2.0 1.6 1.5 1.9 1.9 1.8 1.5 1.9 1.7 1.6 1.8 1.8 1.6 3.2 14.5 1.0 8.8 6.6 2.2 3.6 8.6 6.6 4.1 5.8 3.7 1.5 6.3 5.5 4.2 39.3 6.0 9.5 1.9 2.5 13.2 6.5 7.5 4.3 1.8 45.4 6.3 0.7 40.9 8.0 7.1 9.4 1.3 56.7 0.7 9.9 15.7 11.8 2.7 12.4 6.1 3.8 11.9 8.9 2.8 7.7 33.8 2.8 1.2 2.5 2.1 0.0 2.0 2.1 1.4 3.4 18.5 2.6 2.3 1.0 10.7 10.2 0.0 5.1 7.3 102.6 108.9 16.9 6.0 10.9 7.5 47.5 14.4 2.7 PAIP2B KIAA1155 ENSG00000124374 "Poly(A) binding protein interacting protein 2B" Q9ULR5 2 71182738-71227103 "Predicted intracellular proteins" "Translation regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 181.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 86.0;Early spermatids: 95.1;Hepatocytes: 67.1;Proximal tubular cells: 56.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RPMI-8226: 15.8;SCLC-21H: 23.1" "Low region specificity" "Detected in all" "HPA046784, HPA072371" Approved Approved Cytosol NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 23: Spermatids - Flagellum & Golgi organization" Cytosol "HPA046784: AB_2679804, HPA072371: AB_2686514" "unprognostic (8.70e-2)" "unprognostic (8.20e-2)" "unprognostic (2.55e-1)" "prognostic unfavorable (8.17e-5)" "unprognostic (4.56e-2)" "unprognostic (1.34e-1)" "unprognostic (9.67e-3)" "unprognostic (1.51e-2)" "unprognostic (3.61e-1)" "unprognostic (1.78e-1)" "unprognostic (5.25e-2)" "unprognostic (2.76e-1)" "prognostic favorable (6.96e-12)" "unprognostic (1.63e-2)" "unprognostic (3.87e-1)" "unprognostic (1.21e-2)" "unprognostic (4.61e-2)" 2.4 1.6 131.5 1.8 159.1 1.3 4.5 108.3 176.8 3.1 66.3 3.8 3.7 2.9 1.8 6.1 7.2 1.1 23.0 94.7 116.5 10.3 18.1 2.7 2.1 134.9 136.6 11.5 54.2 6.0 2.2 0.6 143.0 4.8 3.7 27.7 37.9 3.5 48.5 16.4 2.7 1.7 132.8 2.2 10.5 2.2 130.3 2.4 11.6 26.7 4.6 2.8 4.0 181.5 2.5 0.6 1.0 3.6 0.4 0.5 4.4 0.3 0.1 0.3 0.2 0.9 1.0 3.2 0.6 0.0 2.4 2.0 6.1 3.7 1.2 1.7 5.0 3.1 0.4 0.1 1.6 0.8 0.2 0.6 3.3 0.2 3.6 0.9 0.6 7.2 5.5 3.0 0.2 3.2 1.0 1.7 2.6 5.8 2.3 0.0 10.5 15.8 1.9 1.7 23.1 1.3 2.6 1.7 1.1 5.5 7.5 0.2 0.1 0.3 1.9 1.9 1.0 6.1 5.5 3.9 0.2 1.1 0.5 0.5 0.3 0.5 1.0 0.4 1.2 2.5 1.3 1.0 0.4 2.6 2.1 1.9 0.2 0.8 0.4 2.3 0.6 0.6 131.5 159.1 108.3 176.8 94.7 116.5 134.9 136.6 143.0 132.8 130.3 181.5 3.3 3.2 4.5 5.2 9.9 7.8 7.0 4.0 5.7 11.3 14.8 8.8 86.0 12.8 2.7 7.3 6.2 3.2 13.2 2.7 21.5 4.9 95.1 18.4 3.9 3.9 41.5 15.6 4.2 41.3 9.2 4.7 11.2 17.5 1.3 7.5 7.1 67.1 1.9 6.7 4.6 6.3 14.2 3.2 1.6 30.0 5.3 2.6 14.2 2.8 2.4 12.3 4.1 2.5 31.9 10.4 4.0 5.3 29.9 9.4 1.3 56.9 15.5 43.3 0.0 9.3 4.0 32.9 7.7 17.3 20.0 6.3 4.7 4.3 8.1 6.0 PAQR5 "FLJ20190, MPRG" ENSG00000137819 "Progestin and adipoQ receptor family member 5" Q9NXK6 15 69298912-69407780 "Predicted membrane proteins" "Differentiation, Oogenesis" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 52.9" "Cell type enhanced" "Detected in many" "Cholangiocytes: 32.9;Distal tubular cells: 46.9;Early spermatids: 38.2;granulocytes: 67.2;Late spermatids: 123.0;Proximal tubular cells: 42.3" "Cancer enhanced" "Detected in many" "renal cancer: 8.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "basophil: 1.1" "Lineage enriched" "Detected in single" 7 "granulocytes: 1.1" "Cell line enhanced" "Detected in many" "A549: 38.1;CAPAN-2: 46.4;fHDF/TERT166: 33.1;HMC-1: 79.8;U-87 MG: 33.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076729 Approved Vesicles NA NA "Cluster 38: Basophils - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "HPA076729: AB_2686813" "unprognostic (4.47e-2)" "unprognostic (3.11e-2)" "unprognostic (1.46e-1)" "unprognostic (4.05e-4)" "unprognostic (1.53e-1)" "unprognostic (8.28e-2)" "unprognostic (3.58e-3)" "unprognostic (6.12e-3)" "unprognostic (1.47e-1)" "unprognostic (1.67e-1)" "prognostic unfavorable (2.15e-5)" "unprognostic (2.00e-1)" "prognostic favorable (1.47e-14)" "unprognostic (5.64e-2)" "unprognostic (1.73e-1)" "unprognostic (4.16e-4)" "unprognostic (4.94e-2)" 0.6 16.0 3.5 2.6 2.8 1.2 1.2 2.7 3.0 1.7 12.0 19.0 2.3 1.0 0.2 12.4 0.9 2.0 0.8 3.1 2.8 52.9 1.1 9.1 0.3 3.4 3.1 0.6 5.1 11.3 0.8 1.6 4.0 0.6 16.2 1.9 1.8 3.7 0.2 4.9 8.0 0.9 2.8 0.4 7.7 2.4 4.4 0.2 0.8 0.2 2.1 3.6 2.9 2.9 11.7 38.1 0.8 0.8 1.6 4.2 0.3 3.7 22.2 4.3 9.1 2.2 46.4 0.1 5.9 33.1 3.7 0.7 10.9 0.6 7.4 0.1 1.7 6.9 5.6 0.8 2.9 0.2 79.8 2.2 1.7 19.4 20.7 5.5 0.0 0.2 0.1 0.7 18.4 1.6 0.2 0.2 2.6 6.1 3.2 0.1 0.6 2.2 16.6 0.9 3.3 0.7 6.0 2.3 3.1 2.1 1.0 2.8 0.6 13.1 4.2 1.1 0.4 0.2 0.3 0.1 33.1 0.1 3.8 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 3.5 2.8 2.7 3.0 3.1 2.8 3.4 3.1 4.0 2.8 4.4 2.9 0.1 12.8 21.0 1.0 0.5 0.9 1.3 0.4 1.2 0.7 1.3 0.8 0.7 32.9 0.9 20.2 0.0 0.0 0.0 31.1 46.9 19.0 38.2 0.7 0.1 1.9 0.0 0.0 0.5 0.4 0.0 2.8 2.0 1.5 67.2 2.2 0.0 0.0 3.7 0.0 0.7 4.8 0.0 0.3 0.7 123.0 0.9 1.8 0.0 20.6 0.0 5.9 0.0 1.0 0.5 2.6 6.9 1.2 0.0 1.4 26.8 42.3 0.8 0.1 6.6 0.1 0.6 0.5 0.5 15.1 1.8 0.1 0.4 19.6 13.7 0.8 PCOLCE "PCPE, PCPE1" ENSG00000106333 "Procollagen C-endopeptidase enhancer" Q15113 7 100602363-100608175 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 7 "Endometrial stromal cells: 491.6;Fibroblasts: 439.9;Leydig cells: 140.5;Smooth muscle cells: 442.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 879.0;BJ hTERT+: 663.0;fHDF/TERT166: 404.5;HSkMC: 973.2;SH-SY5Y: 689.9;U-2197: 1213.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 81.1" "CAB017623, HPA042927" Approved Approved "Golgi apparatus,Vesicles" "Secreted to extracellular matrix" NA NA 1300000000 "Cluster 22: NK-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 10: Non-specific - Unknown function" "Golgi apparatus, Vesicles" "CAB017623: AB_2251882, HPA042927: AB_2678224" "unprognostic (4.14e-1)" "unprognostic (1.79e-1)" "unprognostic (1.34e-1)" "unprognostic (2.92e-1)" "unprognostic (1.70e-2)" "unprognostic (4.48e-2)" "unprognostic (1.33e-2)" "unprognostic (3.93e-2)" "prognostic unfavorable (9.76e-4)" "unprognostic (2.16e-2)" "unprognostic (1.73e-1)" "unprognostic (6.13e-2)" "prognostic unfavorable (1.68e-5)" "unprognostic (1.04e-2)" "unprognostic (3.21e-2)" "unprognostic (1.63e-2)" "unprognostic (1.43e-2)" 101.5 45.5 2.4 51.5 3.8 0.6 72.6 3.5 10.2 162.8 4.6 30.5 7.8 81.7 11.0 26.9 80.6 112.5 110.8 2.3 2.5 21.9 59.7 72.4 41.3 3.0 2.4 47.7 20.6 10.3 31.2 59.5 2.9 45.5 16.7 0.2 24.9 33.5 16.9 45.0 21.6 59.9 3.1 13.8 22.9 13.7 3.6 10.5 49.1 32.7 17.4 86.4 86.7 2.5 0.2 0.5 2.2 3.0 321.5 879.0 2.4 355.5 663.0 161.1 142.7 14.5 0.8 1.1 1.2 404.5 0.5 0.2 0.0 1.2 15.9 2.5 2.5 0.3 6.1 19.8 82.1 0.1 3.5 973.2 0.3 86.3 0.6 0.4 0.1 1.7 8.3 2.0 0.7 2.1 0.6 3.3 72.2 0.0 4.2 1.0 1.5 0.8 0.4 0.6 1.1 689.9 0.2 2.4 1.6 8.2 2.0 0.0 3.5 391.8 107.6 1213.4 0.2 0.4 0.5 0.1 136.6 1.2 68.2 0.0 0.0 0.4 0.1 0.3 0.3 0.1 0.2 0.1 0.2 0.0 0.1 0.1 0.0 0.4 0.2 0.0 0.1 0.0 2.4 3.8 3.5 10.2 2.3 2.5 3.0 2.4 2.9 3.1 3.6 2.5 33.6 9.6 2.8 2.3 2.5 40.0 3.3 4.2 6.8 4.3 6.6 11.3 16.3 4.3 5.5 5.5 0.0 13.3 4.5 0.8 27.4 6.4 14.8 15.1 491.6 17.2 1.8 5.7 0.5 5.1 11.2 439.9 7.1 11.0 1.3 0.7 33.9 44.8 20.8 16.8 2.5 0.9 6.1 1.9 53.6 27.6 140.5 5.5 32.0 9.4 0.8 12.1 6.2 1.5 0.2 4.1 1.3 50.4 2.1 2.2 0.1 2.5 6.8 2.0 32.9 14.2 442.2 32.8 21.0 3.6 33.1 25.2 9.4 22.6 0.7 3.0 PGC ENSG00000096088 Progastricsin P20142 6 41736711-41754109 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins, Transporters" Digestion "Aspartyl protease, Hydrolase, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 45 "stomach 1: 59821.1" "Group enriched" "Detected in some" 10 "Gastric mucus-secreting cells: 5737.5;Pancreatic endocrine cells: 1449.1" "Cancer enhanced" "Detected in many" "stomach cancer: 1050.3" "Region enhanced" "Detected in single" "cerebellum: 1.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "Hep G2: 253.1;OE19: 152.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA031717, HPA031718" Enhanced Approved Nucleoplasm "Secreted to digestive system" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 4: Stomach - Digestion" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" Nucleoplasm "HPA031717: AB_10670130, HPA031718: AB_10610148" "unprognostic (9.18e-2)" "unprognostic (1.87e-1)" "unprognostic (9.83e-2)" "unprognostic (2.27e-1)" "unprognostic (7.18e-2)" "unprognostic (2.74e-1)" "unprognostic (1.47e-1)" "unprognostic (8.50e-2)" "unprognostic (1.86e-1)" "unprognostic (9.23e-2)" "unprognostic (1.09e-1)" "unprognostic (1.33e-2)" "unprognostic (2.92e-1)" "unprognostic (1.65e-1)" "unprognostic (8.74e-2)" 19.4 7.0 0.0 0.3 0.1 0.2 6.6 1.2 0.5 6.7 0.0 26.4 1327.3 2.8 0.9 85.5 9.2 2.3 6.2 0.1 0.0 4.9 11.0 378.8 0.3 0.0 0.0 3.9 136.3 0.0 7.4 2.8 0.0 83.9 0.3 0.1 4.6 437.7 2.5 3.4 3.2 0.0 0.0 7.7 59821.1 4.2 0.0 0.1 2.2 0.0 0.3 3.8 4.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 15.5 0.0 0.1 0.0 0.0 18.4 0.0 0.0 0.6 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 253.1 0.0 0.3 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.5 0.9 5.7 152.2 0.0 2.9 0.0 6.2 0.0 0.2 0.0 0.7 0.0 0.0 0.0 0.3 0.0 2.8 0.0 0.0 3.7 0.1 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 25.6 335.2 0.0 4.4 0.4 2.8 0.0 0.0 0.0 0.3 0.8 0.3 87.2 5.0 0.0 0.0 1.2 0.0 0.3 0.0 4.6 0.0 0.4 0.0 1.1 0.0 0.0 0.3 131.2 1.5 0.9 5737.5 0.1 10.1 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.3 1.7 0.0 0.0 2.0 0.0 0.0 0.0 0.1 1449.1 2.1 0.0 2.4 85.2 0.1 0.2 3.0 0.0 0.0 0.0 0.6 0.0 0.5 0.0 0.0 4.1 2.6 0.0 0.2 4.2 PGLYRP1 "PGLYRP, PGRP, PGRP-S, PGRPS, TAG7, TNFSF3L" ENSG00000008438 "Peptidoglycan recognition protein 1" O75594 19 46019153-46023053 "Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "bone marrow: 629.4" "Cell type enhanced" "Detected in some" "Erythroid cells: 3.2;Excitatory neurons: 1.7;Inhibitory neurons: 1.5" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebellum: 3.4" "Group enriched" "Detected in some" 202 "eosinophil: 443.7;neutrophil: 494.6" "Lineage enriched" "Detected in many" 213 "granulocytes: 494.6" "Cell line enhanced" "Detected in some" "A549: 3.1;HEK 293: 1.8;HeLa: 1.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045702, HPA070227" Enhanced Approved Nucleoplasm,Vesicles,Cytosol "Secreted to blood" NA NA 35000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 6: Erythroid cells - Oxygen transport" Vesicles "Nucleoplasm, Cytosol" "HPA045702: AB_10960204, HPA070227: " "unprognostic (2.87e-2)" "unprognostic (4.26e-1)" "unprognostic (1.32e-1)" "unprognostic (3.04e-1)" "unprognostic (1.58e-1)" "unprognostic (4.93e-3)" "unprognostic (2.20e-1)" "unprognostic (6.46e-2)" "unprognostic (7.77e-2)" "unprognostic (2.61e-2)" "unprognostic (8.51e-3)" "unprognostic (7.18e-2)" "unprognostic (2.04e-2)" "unprognostic (2.96e-1)" "unprognostic (1.03e-1)" "unprognostic (1.73e-1)" "unprognostic (4.37e-3)" 1.5 0.3 0.3 1.8 1.1 629.4 0.3 3.4 1.5 0.1 0.0 0.3 0.6 0.2 0.0 0.5 0.6 0.2 1.7 0.6 0.0 0.8 2.5 8.7 0.5 0.0 0.1 0.1 0.5 0.0 0.7 0.9 0.0 0.2 0.0 0.0 0.5 0.0 0.3 1.0 0.7 0.1 0.0 42.5 0.4 1.0 0.0 3.3 0.5 2.3 0.0 0.4 0.2 0.0 0.3 3.1 0.5 0.3 0.0 0.0 0.9 0.3 0.0 0.0 0.0 0.5 0.2 0.8 0.1 0.0 0.2 1.2 0.0 0.0 0.0 0.8 1.8 0.3 1.7 0.1 0.0 0.2 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.3 0.3 0.0 0.2 0.2 0.9 0.2 0.0 1.2 0.7 0.1 0.0 0.0 1.2 0.3 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.3 0.4 0.7 0.6 0.3 0.4 0.7 0.0 0.2 0.4 443.7 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 494.6 0.0 2.3 0.0 0.1 3.9 0.3 1.1 3.4 1.5 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 3.2 1.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 1.5 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 PKMYT1 "MYT1, PPP1R126" ENSG00000127564 "Protein kinase, membrane associated tyrosine/threonine 1" Q99640 16 2968024-2980479 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 27.6;testis: 56.9" "Cell type enhanced" "Detected in many" "Erythroid cells: 29.0;Extravillous trophoblasts: 52.0;Plasma cells: 22.9;Spermatocytes: 114.7;Spermatogonia: 46.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 6 "T-reg: 1.3" "Lineage enriched" "Detected in single" 6 "T-cells: 1.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA068860 Supported "Nucleoplasm,Nucleoli,Golgi apparatus" NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 23: Testis - Cell cycle regulation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 12: Non-specific - Cell cycle regulation" "Golgi apparatus" "Nucleoplasm, Nucleoli" "HPA068860: AB_2686050" "unprognostic (7.82e-2)" "unprognostic (8.70e-2)" "unprognostic (5.93e-2)" "unprognostic (2.04e-2)" "unprognostic (4.54e-2)" "unprognostic (1.44e-1)" "prognostic unfavorable (8.33e-4)" "prognostic unfavorable (3.37e-4)" "unprognostic (4.52e-2)" "unprognostic (2.15e-1)" "unprognostic (1.61e-2)" "unprognostic (7.95e-3)" "unprognostic (0.00e+0)" "unprognostic (1.09e-3)" "unprognostic (9.13e-2)" "unprognostic (1.96e-1)" "unprognostic (5.91e-2)" 1.1 1.0 0.4 6.8 0.5 27.6 0.6 1.6 1.4 2.2 0.2 3.9 2.8 0.6 0.3 11.5 0.4 0.6 0.9 0.5 0.2 0.9 1.6 2.0 8.0 0.7 0.6 0.3 1.8 0.1 1.0 3.1 0.8 1.0 1.3 17.4 1.9 0.1 2.4 4.4 4.0 1.0 0.5 5.6 3.3 56.9 0.7 9.6 0.5 0.0 4.5 0.7 3.3 0.8 84.2 57.0 22.0 31.2 0.3 0.9 64.0 65.5 15.1 40.0 38.4 45.0 49.3 54.2 29.2 7.9 24.2 106.7 15.7 20.7 7.2 71.7 56.7 27.9 52.7 40.0 0.0 31.2 73.6 0.7 1.8 24.0 6.5 5.0 8.4 57.6 80.6 87.0 13.5 127.5 83.6 88.0 37.9 39.3 34.4 93.7 51.2 100.7 7.8 17.7 42.6 46.7 31.9 77.7 23.9 12.1 44.7 56.9 7.7 53.2 69.7 77.3 68.0 67.6 54.2 94.0 19.4 40.0 61.2 0.0 0.1 0.1 0.0 0.1 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 1.3 0.3 0.4 0.5 1.6 1.4 0.5 0.2 0.7 0.6 0.8 0.5 0.7 0.8 0.0 0.0 1.1 0.0 1.9 2.5 1.3 2.1 0.6 0.4 1.5 1.3 0.6 1.5 1.6 1.8 6.2 16.0 1.3 5.0 0.0 0.8 20.0 0.6 0.8 0.8 1.8 29.0 0.4 0.6 52.0 2.5 3.1 1.9 0.0 4.5 0.0 0.4 11.8 0.0 0.2 3.6 6.1 2.1 1.8 8.6 0.3 1.9 0.0 0.0 0.7 0.2 0.0 0.0 0.3 0.6 0.3 0.4 22.9 0.7 0.3 0.1 0.2 7.1 0.0 0.1 2.6 114.7 46.1 11.2 0.6 7.4 4.2 0.5 8.6 2.0 PLAC8 "C15, onzin" ENSG00000145287 "Placenta associated 8" Q9NZF1 4 83090048-83137075 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 365.9;esophagus: 92.0;intestine: 236.0;lymphoid tissue: 155.1;stomach 1: 117.5" "Cell type enhanced" "Detected in many" "dendritic cells: 1118.2;Distal enterocytes: 1514.4;Extravillous trophoblasts: 572.2;NK-cells: 1103.0;Paneth cells: 865.7;Respiratory ciliated cells: 549.6" "Cancer enhanced" "Detected in many" "stomach cancer: 17.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 2310.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 183.2;CAPAN-2: 510.7;HL-60: 329.1;NB-4: 160.1;RPMI-8226: 238.2;THP-1: 187.8;U-937: 149.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA040465, HPA077912" Enhanced Approved Cytosol NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA040465: AB_10794875, HPA077912: AB_2686870" "unprognostic (6.82e-5)" "prognostic favorable (3.03e-4)" "unprognostic (3.29e-2)" "unprognostic (4.64e-2)" "unprognostic (2.05e-1)" "unprognostic (4.86e-2)" "unprognostic (1.14e-1)" "unprognostic (1.94e-3)" "unprognostic (1.20e-1)" "unprognostic (1.77e-1)" "unprognostic (7.44e-3)" "unprognostic (1.65e-1)" "unprognostic (1.66e-7)" "unprognostic (3.89e-2)" "unprognostic (2.85e-3)" "unprognostic (1.32e-1)" "unprognostic (1.12e-1)" 9.2 2.0 1.8 81.3 2.0 365.9 3.8 2.8 2.4 32.8 1.4 236.0 78.9 2.7 1.2 92.0 18.7 6.5 2.8 1.5 1.7 2.6 35.4 41.2 93.8 7.8 2.7 1.0 1.6 0.5 2.0 33.7 5.5 3.7 163.3 1.1 6.6 2.3 2.0 1.0 88.5 18.5 2.3 155.1 117.5 0.8 2.4 40.5 2.6 0.8 137.5 11.0 5.8 3.7 183.2 1.3 0.5 1.1 0.0 0.2 28.6 4.6 1.1 11.1 13.7 3.5 510.7 30.7 1.5 52.3 17.0 18.7 3.2 1.4 41.6 0.2 0.6 0.8 33.4 15.2 1.8 329.1 1.7 0.9 3.6 1.8 2.4 0.3 0.8 16.0 0.4 2.6 29.5 0.8 62.6 160.1 1.0 14.4 0.9 8.0 10.6 238.2 0.9 5.4 25.8 0.5 1.2 29.1 0.6 9.0 1.6 187.8 1.3 1.1 31.7 0.9 0.9 1.8 0.4 81.7 2.3 149.7 0.2 49.2 139.2 95.9 392.1 635.8 299.4 523.8 185.1 229.2 129.5 481.1 225.9 263.4 29.7 1053.3 358.9 2310.7 13.8 577.1 1.8 2.0 2.8 2.4 1.5 1.7 7.8 2.7 5.5 2.3 2.4 3.7 4.3 195.5 39.2 0.3 247.4 0.4 1.7 77.3 0.0 0.3 0.9 1.4 0.5 2.8 119.1 0.0 0.0 18.5 1118.2 1514.4 0.0 0.3 0.5 45.6 1.1 95.0 86.8 58.4 0.1 3.6 572.2 3.1 119.8 2.9 26.6 0.6 141.0 8.4 21.7 1.7 0.1 231.2 67.1 384.5 7.4 0.6 0.0 213.3 7.2 1.0 157.3 1.2 1103.0 0.0 0.2 99.0 865.7 0.0 35.7 1.1 374.4 1.4 549.6 0.3 6.6 0.7 8.0 0.2 0.8 10.1 0.1 14.2 150.6 0.1 104.2 9.0 PLK1 PLK ENSG00000166851 "Polo like kinase 1" P53350 16 23677656-23690367 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 32.0;lymphoid tissue: 43.9;testis: 33.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 32.3;Early spermatids: 123.7;Erythroid cells: 38.3;Extravillous trophoblasts: 55.9;Spermatocytes: 79.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "T-reg: 5.6" "Lineage enriched" "Detected in many" 5 "T-cells: 5.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA051638, HPA053229" Approved NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "HPA051638: AB_2681561, HPA053229: AB_2682084" "unprognostic (7.21e-3)" "unprognostic (1.77e-1)" "unprognostic (1.98e-3)" "unprognostic (4.97e-3)" "unprognostic (9.56e-2)" "unprognostic (5.12e-2)" "prognostic unfavorable (2.70e-7)" "prognostic unfavorable (2.28e-5)" "unprognostic (2.55e-2)" "unprognostic (1.89e-1)" "prognostic unfavorable (4.12e-4)" "unprognostic (1.24e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.33e-1)" "unprognostic (8.10e-2)" "unprognostic (1.19e-1)" "unprognostic (1.26e-2)" 1.4 1.5 2.3 13.4 2.3 32.0 1.5 2.5 3.2 2.3 2.0 9.6 10.4 1.2 0.4 13.9 1.0 1.4 1.0 2.3 2.1 1.4 1.9 1.9 27.8 2.3 2.3 1.3 1.1 0.2 1.2 6.4 2.2 1.2 10.1 1.2 2.4 0.3 1.0 5.7 9.2 4.0 2.0 9.1 6.2 33.1 2.5 43.9 0.9 0.4 30.0 2.8 4.0 2.8 199.9 207.5 166.2 90.9 5.2 11.7 92.8 111.0 74.5 172.5 127.0 184.3 131.0 99.1 56.3 76.5 90.1 112.8 229.5 93.5 206.1 139.5 128.0 125.2 163.4 257.1 1.7 147.5 133.7 4.8 5.2 124.7 125.2 21.6 127.9 127.5 200.7 133.9 134.8 187.8 139.8 151.4 189.5 82.1 103.5 217.2 111.7 160.0 49.3 43.9 94.3 65.3 126.8 88.9 55.8 94.4 114.4 92.1 65.1 82.7 102.7 79.9 194.1 93.2 156.8 173.6 69.3 127.7 137.2 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.8 0.3 0.3 0.0 0.0 0.0 0.4 0.9 0.0 0.0 5.6 1.4 2.3 2.3 2.5 3.2 2.3 2.1 2.3 2.3 2.2 2.0 2.5 2.8 0.6 3.2 0.0 3.3 7.6 1.3 1.2 6.5 0.0 1.4 1.7 2.3 0.6 0.0 1.4 0.0 4.2 32.3 0.4 5.5 0.0 0.8 123.7 3.4 1.3 2.5 0.0 38.3 3.1 0.8 55.9 4.7 10.2 1.8 1.3 19.9 3.3 1.1 20.8 0.0 2.3 7.3 4.1 6.9 3.2 13.9 1.2 7.2 0.0 2.8 0.4 1.1 0.0 1.5 2.3 1.2 0.3 0.7 23.0 2.0 1.5 0.1 1.3 1.3 0.0 2.3 6.1 79.5 13.5 12.2 1.8 3.8 2.5 1.2 17.9 2.0 PNPLA1 "dJ50J22.1, FLJ38755" ENSG00000180316 "Patatin like phospholipase domain containing 1" Q8N8W4 6 36243203-36313955 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism" Transferase "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "skin 1: 23.9" "Cell type enhanced" "Detected in some" "Excitatory neurons: 1.9;granulocytes: 4.5;Oligodendrocyte precursor cells: 1.5;Proximal enterocytes: 1.5;Proximal tubular cells: 3.8;Suprabasal keratinocytes: 3.7" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.0" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "basophil: 69.8;eosinophil: 18.9" "Lineage enriched" "Detected in many" 17 "granulocytes: 69.8" "Cell line enriched" "Detected in some" 4 "U-937: 17.6" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 32: U-937 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (3.57e-2)" "unprognostic (2.04e-2)" "unprognostic (1.06e-1)" "unprognostic (3.95e-4)" "unprognostic (1.69e-1)" "unprognostic (1.47e-1)" "unprognostic (7.37e-2)" "unprognostic (2.49e-1)" "unprognostic (8.89e-2)" "unprognostic (1.13e-2)" "unprognostic (2.95e-1)" "unprognostic (2.76e-2)" "unprognostic (2.70e-2)" "unprognostic (9.85e-2)" "unprognostic (2.06e-1)" "unprognostic (2.04e-2)" "unprognostic (1.65e-2)" 0.1 0.2 0.1 0.6 0.2 4.3 0.6 0.3 0.4 0.3 0.0 0.1 0.7 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.1 4.7 0.1 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.1 0.0 0.0 0.2 23.9 0.9 0.2 0.1 0.7 1.7 1.0 0.2 0.1 0.1 0.0 0.1 0.2 0.6 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.7 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 3.9 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.0 17.6 0.0 69.8 4.0 18.9 0.0 2.2 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.2 6.2 0.1 1.1 0.0 0.0 1.1 0.1 0.2 0.3 0.4 0.1 0.1 0.2 0.0 0.2 0.1 0.2 0.3 0.0 0.0 0.0 1.0 0.0 0.9 0.5 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.1 0.0 0.0 1.9 0.0 0.0 0.1 0.0 0.2 4.5 0.7 0.0 0.0 0.2 0.0 1.2 0.4 0.0 0.0 0.3 1.3 0.0 0.1 0.0 0.0 0.7 0.0 0.0 1.5 0.7 0.1 0.0 0.0 0.0 0.1 1.5 3.8 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 3.7 0.1 0.0 0.4 0.2 0.2 PRC1 ASE1 ENSG00000198901 "Protein regulator of cytokinesis 1" O43663 15 90966040-90995629 "Predicted intracellular proteins" "Cell cycle, Cell division" Oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 89.9;testis: 55.0" "Cell type enhanced" "Detected in many" "Erythroid cells: 142.9;Extravillous trophoblasts: 68.3;Spermatocytes: 136.4;Spermatogonia: 74.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 34.4" "Lineage enriched" "Detected in many" 4 "granulocytes: 34.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA034521, HPA048816" Enhanced Supported "Nucleoplasm,Plasma membrane,Microtubules,Cytokinetic bridge,Midbody" Yes Yes "Cluster 38: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Microtubules, Cytokinetic bridge, Midbody" Nucleoplasm "HPA034521: AB_10670169, HPA048816: " "unprognostic (1.14e-1)" "unprognostic (3.98e-2)" "unprognostic (9.21e-2)" "unprognostic (1.75e-3)" "unprognostic (2.39e-1)" "unprognostic (3.43e-2)" "prognostic unfavorable (2.11e-4)" "unprognostic (1.24e-3)" "unprognostic (3.86e-3)" "unprognostic (1.65e-2)" "prognostic unfavorable (2.76e-5)" "unprognostic (2.49e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.09e-2)" "unprognostic (1.79e-1)" "unprognostic (7.90e-2)" "unprognostic (3.92e-2)" 7.4 6.2 6.4 10.0 6.1 89.9 6.4 10.3 8.4 8.1 5.0 16.3 10.6 5.7 2.3 37.6 6.0 3.0 6.9 5.6 4.9 5.6 4.8 9.0 16.9 4.8 5.2 8.1 8.9 2.6 3.6 15.3 5.2 4.9 16.5 4.9 9.5 1.5 4.1 20.1 13.0 9.4 4.9 12.5 11.7 55.0 4.2 43.0 4.3 2.3 24.9 4.8 13.7 5.6 167.9 199.9 164.8 113.6 16.8 28.7 87.5 237.8 139.3 257.2 195.3 134.6 158.5 65.5 91.4 151.9 156.9 220.9 188.8 101.2 240.6 118.7 206.4 135.6 263.5 123.5 4.1 71.4 109.0 7.7 12.8 145.8 146.9 56.6 146.4 100.5 114.0 132.4 241.1 144.4 66.9 98.5 66.6 216.4 84.9 69.7 205.1 86.3 115.3 123.6 151.2 118.9 225.4 121.9 82.7 112.3 149.1 127.1 91.2 168.2 146.0 140.5 345.1 43.5 127.7 80.0 74.5 162.0 265.3 34.4 0.6 2.9 0.6 0.1 0.4 1.1 1.3 1.3 2.4 0.5 1.2 0.4 0.4 3.0 0.3 2.6 8.0 1.0 6.4 6.1 10.3 8.4 5.6 4.9 4.8 5.2 5.2 4.9 4.2 5.6 2.5 0.0 3.1 1.3 6.8 16.6 6.6 8.0 2.2 6.4 3.4 4.3 3.2 0.0 7.6 3.7 0.0 45.5 2.8 16.5 0.0 3.2 41.5 4.5 4.0 4.7 5.4 142.9 5.0 2.9 68.3 7.2 16.3 6.8 8.9 13.2 9.3 2.1 21.5 3.3 5.2 17.0 10.2 8.7 15.0 15.4 3.7 5.2 3.6 1.9 5.5 3.8 4.1 2.0 1.7 2.3 3.2 1.9 17.5 5.9 2.0 0.1 3.2 4.6 6.6 7.4 10.9 136.4 74.2 38.0 14.2 14.6 6.8 0.4 24.1 6.7 PRR36 ENSG00000183248 "Proline rich 36" Q9H6K5 19 7868719-7874390 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 21.0;pituitary gland: 29.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 13.4;Breast glandular cells: 9.2;Cone photoreceptor cells: 12.5;Horizontal cells: 10.1" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 21.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "REH: 28.7;SCLC-21H: 8.0;SH-SY5Y: 17.9;T-47d: 9.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062741 Uncertain Approved "Nucleoplasm,Nuclear speckles,Golgi apparatus" Yes No "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 14: REH - Unknown function" "Cluster 35: Glandular cells - Unknown function" "Golgi apparatus" "Nucleoplasm, Nuclear speckles" "HPA062741: AB_2684860" "unprognostic (3.15e-2)" "unprognostic (1.02e-1)" "unprognostic (6.23e-2)" "unprognostic (5.61e-2)" "unprognostic (1.72e-1)" "unprognostic (1.20e-2)" "unprognostic (9.62e-2)" "unprognostic (3.46e-3)" "unprognostic (1.18e-1)" "unprognostic (1.15e-3)" "unprognostic (1.75e-2)" "unprognostic (2.99e-1)" "unprognostic (5.69e-3)" "unprognostic (7.89e-2)" "prognostic favorable (7.74e-4)" "unprognostic (3.56e-1)" "unprognostic (8.52e-3)" 0.1 0.9 3.5 0.1 4.0 0.0 2.5 3.0 21.0 0.8 0.0 0.3 0.2 0.6 0.3 0.3 1.2 0.1 0.2 7.5 0.0 3.3 0.2 0.9 0.0 0.0 0.0 0.7 2.8 2.0 29.6 0.0 0.0 2.5 0.0 5.0 4.1 0.3 0.0 0.7 0.2 0.0 0.0 0.1 0.8 0.8 0.0 0.0 1.1 0.0 0.0 0.3 0.3 0.0 0.1 0.9 6.6 5.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 1.4 2.9 0.0 1.9 0.0 0.6 0.1 5.1 0.0 0.0 0.0 6.4 0.0 0.3 1.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 3.2 0.1 0.1 0.0 3.0 0.3 0.3 2.5 0.4 0.6 28.7 0.0 0.3 3.7 5.4 8.0 17.9 0.0 0.3 0.0 0.5 9.1 0.0 0.0 0.0 3.2 0.1 0.0 1.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 4.0 3.0 21.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.0 0.5 0.0 0.8 0.0 2.2 13.4 9.2 7.7 1.3 2.8 0.0 5.5 12.5 0.2 0.2 0.2 5.9 3.0 5.4 4.5 0.7 0.2 3.6 0.0 6.9 0.9 0.4 0.3 2.6 6.7 0.0 1.1 0.0 0.5 0.1 10.1 5.8 0.7 0.0 0.0 0.0 0.7 0.6 0.4 0.0 3.7 0.0 5.4 0.0 4.5 0.8 0.9 0.1 0.0 0.6 1.3 0.1 1.5 0.0 4.5 0.0 0.3 1.1 0.3 3.7 3.1 0.0 0.3 0.3 0.5 0.3 1.0 PRSS3 "PRSS4, TRY3, TRY4" ENSG00000010438 "Serine protease 3" P35030 9 33750679-33799231 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 268 "pancreas: 31113.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 1022.9;Exocrine glandular cells: 2040.4;Pancreatic endocrine cells: 478.8;Paneth cells: 969.9;Proximal enterocytes: 1127.1" "Group enriched" "Detected in many" 7 "colorectal cancer: 72.8;pancreatic cancer: 104.4;stomach cancer: 43.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 104 "basophil: 158.7" "Lineage enriched" "Detected in many" 104 "granulocytes: 158.7" "Group enriched" "Detected in many" 5 "OE19: 316.6;PC-3: 852.5" "HPA062452, HPA063471" Supported Approved "Endoplasmic reticulum,Vesicles" "Secreted to digestive system" NA NA 700000000 "Cluster 38: Basophils - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "Endoplasmic reticulum" "HPA062452: AB_2684768, HPA063471: AB_2685017" "unprognostic (6.90e-2)" "unprognostic (2.26e-1)" "unprognostic (1.69e-2)" "prognostic unfavorable (4.30e-4)" "unprognostic (3.18e-1)" "unprognostic (1.64e-1)" "unprognostic (3.29e-2)" "unprognostic (5.89e-3)" "unprognostic (1.38e-1)" "unprognostic (2.06e-3)" "unprognostic (1.10e-2)" "unprognostic (8.94e-2)" "unprognostic (7.75e-4)" "unprognostic (5.46e-3)" "unprognostic (2.13e-1)" "unprognostic (8.79e-2)" "unprognostic (4.96e-1)" 3.8 4.6 23.5 7.2 29.3 0.6 1.7 25.8 35.4 30.8 16.9 87.0 92.6 0.4 0.0 116.2 0.3 22.8 6.3 28.2 25.6 3.7 12.4 0.6 0.7 25.0 24.5 12.9 31113.6 0.0 0.7 1.7 25.7 1.1 77.8 0.3 20.9 0.3 0.5 79.7 105.4 3.1 19.4 0.7 22.8 5.1 25.6 0.8 0.4 0.0 15.2 4.2 56.9 24.7 12.0 13.7 0.7 0.0 0.2 5.9 0.1 33.6 7.7 4.1 1.6 34.3 3.0 0.0 0.2 14.9 0.2 15.0 0.0 31.7 10.1 0.4 0.2 0.0 1.1 0.0 2.7 0.0 0.0 0.2 0.0 10.8 110.2 0.3 68.8 0.2 0.0 0.0 0.0 0.2 0.7 0.4 0.2 316.6 852.5 0.0 0.0 0.0 0.0 1.7 0.3 81.2 0.2 0.0 0.0 0.5 0.0 0.0 78.3 0.0 0.0 12.8 0.0 0.0 0.0 0.1 18.1 0.0 0.1 158.7 0.0 0.0 0.2 1.5 1.2 0.0 0.2 0.4 0.5 0.0 0.0 0.0 0.0 0.4 1.5 0.0 0.0 0.3 23.5 29.3 25.8 35.4 28.2 25.6 25.0 24.5 25.7 19.4 25.6 24.7 0.1 0.0 0.0 0.7 1.9 57.1 0.6 1.3 0.0 0.2 0.1 2.8 1.0 47.1 1.2 1.8 0.0 0.0 0.1 1022.9 3.9 43.2 31.4 0.0 0.0 3.2 192.6 0.0 32.8 2040.4 0.0 0.8 39.3 0.0 8.9 0.0 0.7 4.2 0.0 0.0 4.7 146.4 0.0 0.3 12.1 79.7 1.5 1.2 7.2 3.7 5.7 0.0 0.0 3.5 1.2 478.8 969.9 0.7 0.3 12.1 1127.1 14.7 0.1 0.2 0.0 0.0 1.7 0.5 0.9 1.1 134.1 0.1 2.1 0.0 329.0 56.2 PTK6 BRK ENSG00000101213 "Protein tyrosine kinase 6" Q13882 20 63528001-63537376 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 109.4;skin 1: 53.9;vagina: 43.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 132.1;Gastric mucus-secreting cells: 59.1;Intestinal goblet cells: 42.5;Paneth cells: 97.6;Proximal enterocytes: 80.2;Squamous epithelial cells: 48.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "A-431: 22.1;CAPAN-2: 41.4;HaCaT: 33.9;hTCEpi: 45.0;OE19: 57.0;RT4: 26.4;T-47d: 25.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB032952, HPA036070, HPA036071" Approved Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Nuclear bodies, Plasma membrane, Cytosol" "CAB032952: AB_634461, HPA036070: AB_10602292, HPA036071: AB_10669982" "unprognostic (2.32e-2)" "unprognostic (1.36e-1)" "unprognostic (1.05e-1)" "unprognostic (2.42e-2)" "unprognostic (1.41e-1)" "unprognostic (1.35e-1)" "unprognostic (1.04e-1)" "unprognostic (2.29e-1)" "unprognostic (3.03e-1)" "unprognostic (3.72e-2)" "prognostic unfavorable (1.96e-4)" "unprognostic (1.28e-1)" "prognostic unfavorable (1.26e-9)" "unprognostic (4.19e-2)" "unprognostic (1.74e-1)" "unprognostic (1.73e-1)" "unprognostic (4.24e-2)" 0.5 0.1 0.6 3.6 1.7 0.8 3.8 2.9 1.7 19.8 0.0 26.5 28.9 0.4 0.1 109.4 0.4 3.5 0.2 0.6 0.9 0.8 5.2 2.6 0.6 1.6 1.0 0.3 3.6 0.0 0.2 0.3 1.7 3.1 15.7 0.8 19.1 0.6 0.6 53.9 22.2 0.8 0.6 0.8 26.2 0.3 1.1 0.3 0.2 0.0 6.4 9.8 43.2 5.4 22.1 2.6 0.3 0.3 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.5 41.4 0.1 7.2 0.0 0.1 33.9 0.0 0.1 0.0 5.4 0.4 0.0 10.2 0.1 0.1 0.0 6.7 0.0 45.0 0.0 0.2 0.2 0.0 0.1 0.2 2.5 0.2 12.5 0.0 0.2 0.2 57.0 15.5 0.1 1.2 0.5 0.0 26.4 0.3 2.2 2.6 8.1 0.0 0.1 25.2 1.6 0.2 0.3 0.4 0.8 0.3 0.5 0.1 0.1 0.4 0.5 1.1 0.4 0.7 0.1 0.1 0.5 0.5 0.3 0.1 0.0 1.3 0.3 0.1 0.1 0.3 0.0 0.4 0.1 0.1 0.3 0.6 1.7 2.9 1.7 0.6 0.9 1.6 1.0 1.7 0.6 1.1 5.4 0.3 12.8 25.6 0.3 1.4 5.9 2.6 7.7 5.2 2.2 7.0 4.3 0.4 12.8 14.9 0.0 2.1 0.2 0.2 132.1 0.0 1.4 0.2 0.4 0.5 3.2 5.4 0.0 0.1 1.6 0.2 1.4 59.1 1.3 9.5 0.2 0.4 1.7 0.6 0.0 0.1 42.5 2.0 2.2 2.0 0.0 0.3 2.6 0.0 0.0 1.0 1.6 1.0 0.0 0.8 17.6 97.6 0.0 0.1 1.5 80.2 0.2 8.9 3.7 0.0 2.3 1.1 0.2 0.3 48.0 15.5 0.1 2.0 0.2 32.1 15.9 PTPRB PTPB ENSG00000127329 "Protein tyrosine phosphatase receptor type B" P23467 12 70515870-70637440 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 215.9;Endothelial cells: 211.5;Hepatic stellate cells: 504.0;Microglial cells: 164.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 24.3;hTERT-RPE1: 19.7;HUVEC TERT2: 61.4;TIME: 90.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004782, HPA067868" Uncertain Approved "Vesicles,Plasma membrane,Cell Junctions" NA NA 14000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Vesicles, Cell Junctions" "CAB004782: , HPA067868: AB_2685911" "unprognostic (3.18e-1)" "unprognostic (2.99e-6)" "unprognostic (1.56e-1)" "unprognostic (1.80e-1)" "unprognostic (3.55e-2)" "unprognostic (1.77e-2)" "prognostic favorable (6.05e-4)" "unprognostic (4.59e-1)" "unprognostic (2.22e-2)" "unprognostic (1.85e-1)" "unprognostic (2.28e-2)" "unprognostic (1.40e-1)" "prognostic favorable (1.02e-4)" "unprognostic (2.91e-2)" "unprognostic (7.18e-2)" "unprognostic (1.31e-1)" "unprognostic (1.38e-1)" 26.7 9.4 16.0 4.7 14.1 0.1 18.8 12.3 12.1 12.8 7.1 10.9 7.5 12.3 4.4 6.8 10.8 14.7 23.2 10.1 12.4 22.5 16.7 35.7 3.2 15.9 14.2 4.0 6.2 7.8 4.7 32.6 18.1 6.3 11.1 1.4 3.3 8.0 17.1 4.1 9.3 18.1 12.4 30.0 6.2 2.5 19.0 3.0 14.8 38.8 3.4 7.7 5.3 11.9 4.4 0.3 1.9 0.2 0.0 0.1 0.9 0.9 4.2 2.2 5.2 0.1 3.4 1.7 24.3 0.6 0.4 15.2 0.2 0.7 7.8 1.3 0.7 0.4 1.7 1.1 0.2 0.7 0.0 0.1 0.7 6.1 0.0 19.7 61.4 0.0 3.6 1.0 1.3 0.0 0.1 0.0 2.3 4.4 0.9 0.1 1.6 0.9 11.3 1.8 0.0 0.8 1.6 0.0 3.5 0.4 0.0 1.5 90.3 0.9 0.9 0.4 5.4 1.1 0.9 0.8 0.4 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 16.0 14.1 12.3 12.1 10.1 12.4 15.9 14.2 18.1 12.4 19.0 11.9 215.9 0.0 13.2 2.0 3.1 3.7 0.8 1.0 0.0 7.1 0.9 0.9 12.3 11.5 1.3 3.7 0.0 0.0 2.0 12.8 0.0 1.5 4.6 2.2 0.7 211.5 0.0 16.0 52.5 0.9 0.0 7.3 1.5 4.0 25.2 0.5 504.0 4.7 0.4 5.0 68.8 6.4 0.0 20.0 4.6 3.0 1.2 1.2 5.4 164.9 0.0 0.4 0.0 2.5 2.9 12.2 11.1 0.0 0.1 0.8 3.2 0.1 0.2 0.9 0.0 6.4 5.2 0.7 0.7 0.9 1.6 0.0 1.0 1.8 6.8 0.7 RAPGEF4 "cAMP-GEFII, CGEF2" ENSG00000091428 "Rap guanine nucleotide exchange factor 4" Q8WZA2 2 172735274-173052893 "Predicted intracellular proteins" Exocytosis "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 142.3" "Group enriched" "Detected in many" 7 "Excitatory neurons: 441.1;Inhibitory neurons: 416.6;Microglial cells: 142.4;Oligodendrocyte precursor cells: 303.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 21.5;SCLC-21H: 8.3;U-266/70: 11.0;U-266/84: 23.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004388, HPA028968" Approved Approved "Focal adhesion sites" NA NA "Cluster 65: Brain - Ion transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Focal adhesion sites" "CAB004388: AB_670916, HPA028968: AB_2672846" "unprognostic (1.87e-1)" "unprognostic (4.22e-2)" "unprognostic (1.31e-1)" "unprognostic (2.98e-3)" "unprognostic (4.53e-2)" "unprognostic (1.20e-2)" "unprognostic (4.45e-2)" "unprognostic (1.80e-1)" "unprognostic (1.16e-1)" "unprognostic (3.23e-1)" "prognostic favorable (1.32e-4)" "unprognostic (6.32e-2)" "unprognostic (1.46e-3)" "unprognostic (1.97e-2)" "unprognostic (6.18e-2)" "unprognostic (5.70e-2)" "unprognostic (2.93e-1)" 5.3 45.6 105.0 1.8 113.1 0.2 6.8 69.8 141.6 6.1 49.1 2.1 2.4 5.6 3.1 2.6 3.4 4.7 7.5 142.3 77.7 5.3 34.6 11.4 2.0 61.2 75.0 13.1 4.5 4.0 6.2 2.6 60.8 4.1 1.6 18.8 2.4 3.3 1.5 14.9 2.3 5.4 55.7 0.6 7.7 4.7 128.3 2.2 5.5 1.7 2.0 5.3 3.2 121.9 0.1 0.2 3.2 0.5 0.1 0.3 0.1 1.1 0.7 0.1 0.3 0.0 3.7 0.0 0.2 0.0 0.2 0.7 2.8 0.7 0.3 0.2 5.9 0.6 2.8 0.0 0.0 3.2 0.9 0.1 0.9 0.0 0.0 3.2 3.5 1.6 0.0 21.5 0.1 0.1 0.2 0.2 0.4 1.8 0.4 0.1 0.7 0.0 0.0 6.6 8.3 3.0 0.1 0.1 1.1 1.6 0.1 0.1 1.0 0.1 0.3 0.0 0.3 11.0 23.0 0.0 0.4 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 105.0 113.1 69.8 141.6 142.3 77.7 61.2 75.0 60.8 55.7 128.3 121.9 14.7 3.2 2.8 23.2 1.9 6.1 1.1 0.1 2.8 3.5 5.5 3.9 6.9 0.0 0.0 0.0 45.9 0.1 0.1 0.0 0.0 1.7 2.5 1.2 0.2 32.4 7.8 0.0 441.1 2.7 0.1 4.8 3.1 0.9 0.0 3.3 23.9 11.8 0.1 1.7 416.6 0.5 0.0 1.2 2.1 1.4 4.4 0.2 3.6 142.4 0.0 1.3 0.0 303.1 28.4 1.5 0.1 1.5 1.6 0.5 0.0 0.0 0.0 9.2 0.0 0.4 1.2 0.7 4.1 1.6 3.8 0.1 0.6 4.2 0.1 0.7 RAPGEFL1 Link-GEFII ENSG00000108352 "Rap guanine nucleotide exchange factor like 1" Q9UHV5 17 40177010-40195656 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 199.1;skin 1: 237.7;vagina: 113.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 87.7;Excitatory neurons: 47.8;Proximal enterocytes: 55.3;Squamous epithelial cells: 95.4;Suprabasal keratinocytes: 97.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "HaCaT: 92.4;hTCEpi: 45.8;T-47d: 80.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022895 Approved "Nucleoplasm,Microtubules,Cytokinetic bridge" Yes No "Cluster 1: Neutrophils - Mixed function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoplasm, Microtubules" "Cytokinetic bridge" "HPA022895: AB_1856071" "prognostic favorable (8.43e-4)" "prognostic favorable (3.28e-4)" "unprognostic (1.61e-1)" "unprognostic (1.13e-2)" "unprognostic (4.64e-3)" "unprognostic (3.48e-2)" "unprognostic (5.92e-2)" "unprognostic (1.80e-1)" "unprognostic (3.64e-2)" "unprognostic (2.67e-1)" "unprognostic (7.46e-3)" "unprognostic (8.84e-3)" "prognostic unfavorable (0.00e+0)" "unprognostic (7.23e-2)" "unprognostic (1.50e-1)" "unprognostic (1.15e-1)" "unprognostic (2.03e-2)" 6.3 4.4 38.4 6.8 36.1 4.4 9.1 12.1 58.3 48.7 1.8 53.8 48.3 4.6 9.9 199.1 6.6 8.8 6.8 55.1 12.9 3.8 10.5 8.0 2.2 12.0 11.4 3.7 7.9 1.1 14.2 2.3 10.9 17.7 44.5 6.1 27.4 6.9 12.6 237.7 40.6 4.0 8.3 7.3 31.8 10.2 15.2 3.3 4.5 2.8 20.7 21.9 113.2 30.6 5.3 2.6 13.7 10.2 1.5 3.3 6.6 1.9 1.4 2.7 3.2 6.0 7.6 4.2 1.9 2.7 2.4 92.4 2.7 3.3 3.8 7.7 6.9 2.5 3.6 6.0 1.7 5.2 8.5 3.9 45.8 2.8 1.3 4.0 4.1 13.9 1.9 2.8 2.1 14.6 4.9 6.3 4.3 26.1 2.6 8.8 1.6 2.6 1.7 27.6 26.2 5.3 3.3 31.2 1.3 11.5 80.7 3.9 7.9 3.3 6.8 3.5 3.2 4.6 4.7 3.4 7.8 3.2 4.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 38.4 36.1 12.1 58.3 55.1 12.9 12.0 11.4 10.9 8.3 15.2 30.6 1.9 0.0 1.1 7.5 1.0 45.5 9.7 14.0 13.1 5.7 2.6 3.7 2.4 11.5 10.9 1.8 6.2 0.2 0.7 87.7 0.0 0.9 2.7 5.9 2.1 2.2 4.9 2.7 47.8 0.8 0.3 1.4 32.6 9.4 5.7 1.7 3.9 4.4 0.5 1.7 32.1 31.9 6.1 1.2 5.2 2.2 3.4 1.9 5.4 1.0 2.4 2.9 1.0 8.0 5.0 1.6 44.6 3.8 0.1 10.9 55.3 0.1 6.5 4.4 0.0 2.1 1.9 12.0 15.0 95.4 97.0 0.7 1.1 1.8 44.1 39.2 RDH13 SDR7C3 ENSG00000160439 "Retinol dehydrogenase 13" Q8NBN7 19 55039108-55071291 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 209.7;Urothelial cells: 110.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEK 293: 60.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042006 Approved Supported Mitochondria,Cytosol "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Mitochondria, Cytosol" "HPA042006: AB_10960270" "unprognostic (9.26e-2)" "unprognostic (1.14e-2)" "unprognostic (1.08e-1)" "unprognostic (2.15e-2)" "unprognostic (8.74e-2)" "unprognostic (1.08e-2)" "unprognostic (2.48e-1)" "unprognostic (3.60e-2)" "unprognostic (1.82e-1)" "unprognostic (9.42e-3)" "unprognostic (1.61e-1)" "unprognostic (2.45e-3)" "prognostic favorable (2.09e-4)" "unprognostic (2.19e-2)" "unprognostic (2.23e-1)" "unprognostic (2.12e-2)" "unprognostic (1.66e-3)" 4.5 4.8 2.5 3.4 2.6 2.2 4.5 3.9 3.6 9.4 3.9 8.6 6.7 4.2 0.7 19.8 4.8 3.0 13.0 2.4 3.5 9.2 8.2 4.4 3.5 3.5 4.2 3.7 8.6 12.4 6.4 10.1 3.7 6.3 3.8 2.1 9.6 3.7 9.7 21.0 6.1 2.0 1.6 6.2 10.5 5.3 3.8 2.2 7.5 4.8 2.7 5.1 12.2 2.3 10.9 12.3 2.9 10.3 1.5 3.0 17.9 3.4 2.1 3.7 6.4 23.3 15.7 9.4 5.3 1.2 2.7 14.1 7.8 7.2 1.7 7.3 60.0 12.2 9.8 14.6 2.9 12.4 8.0 2.6 6.3 3.0 2.9 3.7 3.0 5.2 27.2 2.9 2.3 13.4 6.1 9.6 2.5 17.7 25.7 15.7 6.7 27.6 8.2 37.3 8.8 6.2 8.9 31.3 7.0 2.7 12.0 9.3 3.0 0.3 3.7 0.1 8.2 7.8 11.0 9.6 9.1 10.6 6.6 3.8 4.1 4.1 8.2 6.3 7.7 5.4 6.3 7.6 4.2 5.8 8.4 6.1 1.9 7.8 5.0 6.4 5.5 3.0 2.5 2.6 3.9 3.6 2.4 3.5 3.5 4.2 3.7 1.6 3.8 2.3 8.9 16.0 13.1 3.9 6.6 10.7 31.7 11.1 7.4 21.0 12.2 9.9 27.5 20.0 19.3 14.7 41.7 41.3 9.4 47.2 11.7 13.5 24.3 18.3 8.8 9.1 12.0 4.2 9.4 6.5 29.0 7.1 46.4 31.8 8.2 24.4 18.5 7.3 11.5 25.2 10.0 27.5 12.2 4.9 5.0 13.2 3.7 4.2 7.2 4.7 5.0 9.0 6.2 5.0 2.9 14.5 35.7 3.4 8.7 30.6 20.3 4.8 12.8 25.3 6.6 5.1 6.5 3.2 8.9 11.1 17.5 209.7 9.2 11.1 28.1 110.1 RHBDL2 FLJ20435 ENSG00000158315 "Rhomboid like 2" Q9NX52 1 38885807-38941830 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 24.4" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 74.6;Club cells: 44.8;Distal enterocytes: 52.2;Ionocytes: 46.8;Oligodendrocytes: 53.9;Pancreatic endocrine cells: 53.0;Urothelial cells: 49.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "A-431: 12.7;CAPAN-2: 41.7;HaCaT: 21.7;RT4: 40.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA043807 Approved NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA043807: AB_10961118" "unprognostic (3.34e-2)" "unprognostic (2.96e-1)" "unprognostic (4.57e-2)" "unprognostic (2.56e-1)" "unprognostic (7.26e-3)" "unprognostic (2.19e-2)" "unprognostic (1.04e-3)" "unprognostic (5.81e-2)" "unprognostic (2.36e-1)" "unprognostic (2.87e-1)" "unprognostic (4.07e-3)" "unprognostic (1.23e-1)" "unprognostic (7.47e-9)" "unprognostic (1.11e-2)" "unprognostic (2.46e-1)" "unprognostic (4.12e-2)" "unprognostic (4.20e-2)" 2.2 0.4 4.1 1.7 8.8 0.4 2.0 5.6 7.1 4.3 0.3 18.0 1.3 0.6 0.2 24.4 1.1 3.4 7.7 4.0 4.9 0.9 0.4 1.0 0.8 10.0 9.5 0.3 0.6 0.3 1.3 1.1 7.3 1.8 18.0 1.1 7.8 0.5 0.5 16.6 0.8 1.1 4.1 0.4 15.7 7.3 7.4 0.7 0.7 0.0 7.1 9.7 12.8 11.4 12.7 4.3 0.4 0.2 0.2 1.2 1.2 0.7 0.1 0.9 0.1 0.9 41.7 0.3 3.0 6.3 4.2 21.7 0.0 7.1 0.6 0.3 0.2 0.2 2.9 2.5 0.5 0.1 0.5 0.9 1.0 6.0 0.1 4.0 1.0 0.4 0.0 0.4 0.9 0.0 0.1 0.3 0.2 1.3 1.2 0.2 0.2 0.0 0.0 40.4 0.4 0.3 5.0 11.4 0.4 0.6 5.6 0.4 0.9 4.4 0.5 0.3 0.3 0.4 0.5 0.5 4.1 0.8 0.2 1.5 0.6 0.4 0.2 0.4 0.1 0.7 0.2 0.1 0.7 0.3 0.2 0.2 1.7 0.3 0.2 0.7 0.3 0.3 4.1 8.8 5.6 7.1 4.0 4.9 10.0 9.5 7.3 4.1 7.4 11.4 1.3 0.0 0.5 11.1 0.7 17.7 8.0 74.6 5.2 2.7 3.9 2.4 0.4 5.7 44.8 3.7 0.0 0.4 0.2 52.2 0.0 12.4 3.9 4.7 3.4 1.4 2.4 0.0 19.0 15.8 0.3 2.1 27.5 8.4 4.5 1.6 1.8 0.0 0.2 1.7 21.9 17.3 46.8 0.0 2.7 1.0 0.6 0.4 1.8 4.7 0.6 1.3 0.0 10.6 53.9 53.0 22.3 0.0 0.2 13.4 0.2 0.3 33.2 1.8 6.6 1.2 4.0 0.3 0.1 19.0 28.4 0.7 0.5 0.2 30.2 49.9 RHOF "ARHF, FLJ20247, RIF" ENSG00000139725 "Ras homolog family member F, filopodia associated" Q9HBH0 12 121777754-121803403 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 273.9;Langerhans cells: 224.9;monocytes: 241.2;Pancreatic endocrine cells: 191.7;Paneth cells: 279.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 129.0;HDLM-2: 177.1;PC-3: 147.3;RPTEC TERT1: 127.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045912, HPA076019" Enhanced Supported Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Golgi apparatus" "HPA045912: , HPA076019: AB_2732299" "unprognostic (1.26e-1)" "unprognostic (8.73e-2)" "unprognostic (2.05e-1)" "unprognostic (3.40e-2)" "unprognostic (1.90e-1)" "unprognostic (4.26e-5)" "unprognostic (1.38e-3)" "unprognostic (2.37e-4)" "unprognostic (1.34e-1)" "unprognostic (5.51e-2)" "unprognostic (1.10e-4)" "unprognostic (1.10e-1)" "unprognostic (5.01e-3)" "unprognostic (1.30e-1)" "unprognostic (2.02e-2)" "unprognostic (7.51e-4)" "unprognostic (1.14e-1)" 6.5 13.3 11.5 26.6 9.9 47.4 5.5 21.6 12.0 14.3 10.6 24.3 31.8 13.2 21.8 11.7 10.0 9.8 15.0 10.4 11.0 16.2 3.9 20.6 41.0 13.0 12.2 8.9 6.1 7.7 5.1 5.7 13.4 9.2 19.3 9.9 11.5 9.8 11.8 9.2 32.3 11.5 8.7 33.3 28.2 9.0 10.6 25.6 14.6 2.8 31.4 9.1 7.3 11.7 58.3 69.2 12.4 15.3 4.4 6.4 5.6 5.3 5.2 2.5 4.4 28.8 129.0 6.3 42.6 6.0 1.4 8.6 23.2 33.7 2.2 177.1 8.0 37.9 47.5 27.7 10.1 38.6 25.8 9.0 7.5 5.4 2.9 23.8 17.6 44.7 5.6 9.9 1.4 41.7 50.7 56.7 10.4 13.6 147.3 26.5 0.7 10.8 127.9 4.9 9.9 9.4 38.5 4.5 2.6 5.6 19.9 15.0 21.4 4.0 40.1 12.5 1.5 12.3 7.6 20.0 5.0 42.9 2.6 23.8 10.9 41.5 97.0 36.5 92.7 55.5 77.2 82.5 31.0 45.2 59.5 73.2 24.4 61.4 69.8 74.3 90.2 43.3 11.5 9.9 21.6 12.0 10.4 11.0 13.0 12.2 13.4 8.7 10.6 11.7 3.1 38.5 10.7 1.0 54.1 8.7 1.9 5.5 3.4 8.1 9.3 3.8 1.5 15.7 11.3 23.9 0.0 2.7 111.8 273.9 41.1 34.0 20.2 16.5 5.6 3.5 6.7 12.2 5.3 55.3 3.9 5.3 50.4 37.1 20.8 13.1 10.0 4.0 14.4 0.0 3.9 28.6 2.0 10.9 224.9 53.8 4.1 40.3 21.4 3.7 241.2 4.7 103.0 1.0 1.2 191.7 279.6 2.2 39.4 3.8 121.6 15.1 13.5 9.7 6.6 2.6 4.5 17.7 2.9 2.5 13.2 5.5 99.2 23.4 17.3 44.3 RIBC2 "C22orf11, DKFZp566F0546, FLJ25720" ENSG00000128408 "RIB43A domain with coiled-coils 2" Q9H4K1 22 45413693-45432509 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "choroid plexus: 14.4;fallopian tube: 9.8;testis: 30.7" "Cell type enhanced" "Detected in some" "Early spermatids: 218.6;Endometrial ciliated cells: 77.5;Late spermatids: 40.4;Respiratory ciliated cells: 101.4;Spermatocytes: 159.4" "Cancer enhanced" "Detected in many" "cervical cancer: 8.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 7.6;CAPAN-2: 7.7;MCF7: 9.2;SiHa: 13.0" "Not detected" "Not detected" "Region enhanced" "Detected in many" "midbrain: 14.9" HPA003210 Approved NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 20: HeLa - Mitochondria" "Cluster 49: Ciliated cells - Cilium organization" "HPA003210: AB_1078347" "unprognostic (2.55e-1)" "prognostic favorable (7.08e-8)" "unprognostic (3.58e-1)" "unprognostic (1.53e-2)" "unprognostic (1.24e-1)" "unprognostic (1.71e-2)" "unprognostic (1.30e-3)" "unprognostic (9.51e-3)" "unprognostic (7.21e-3)" "unprognostic (7.34e-2)" "unprognostic (1.01e-1)" "unprognostic (7.37e-2)" "unprognostic (9.95e-5)" "unprognostic (1.41e-1)" "unprognostic (5.32e-2)" "unprognostic (7.91e-2)" "unprognostic (1.13e-1)" 0.0 0.1 0.9 0.6 0.9 1.9 0.2 0.3 0.3 0.9 14.4 0.5 0.3 0.6 0.4 0.7 9.8 0.4 0.0 0.6 0.5 0.1 0.0 0.8 0.4 2.5 2.6 0.2 0.2 1.2 1.4 0.3 1.7 0.6 0.3 0.2 0.2 0.1 0.0 0.9 0.5 0.2 1.6 0.1 0.5 30.7 0.8 0.5 0.5 0.0 0.4 0.1 0.5 2.2 5.9 4.0 0.6 0.0 0.0 0.0 0.5 7.6 0.6 1.5 2.1 4.2 7.7 0.0 1.8 0.7 0.0 6.8 0.0 0.0 1.1 0.0 0.2 0.0 5.7 0.2 0.0 0.0 0.9 0.0 0.0 0.8 0.0 0.0 0.8 0.9 0.0 0.0 0.5 9.2 4.0 2.0 0.9 0.1 2.2 4.5 0.0 0.0 2.1 0.8 3.9 0.0 13.0 2.6 0.0 0.4 4.8 2.8 0.4 0.0 0.0 4.6 0.0 2.2 2.3 0.0 0.0 1.2 3.5 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.9 0.9 0.3 0.3 0.6 0.5 2.5 2.6 1.7 1.6 0.8 2.2 0.2 0.0 0.0 0.0 0.1 0.3 0.8 3.6 0.0 0.0 0.6 0.8 0.2 1.5 7.7 0.0 0.0 1.5 0.4 0.8 1.9 0.1 218.6 77.5 1.8 0.3 0.0 4.0 0.9 0.0 0.6 0.9 0.5 2.5 0.0 0.6 0.0 0.0 1.1 0.0 0.3 1.8 12.2 0.0 0.4 40.4 1.2 0.7 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.0 0.1 0.7 0.1 0.4 0.1 0.0 101.4 3.6 0.0 0.0 1.9 159.4 22.2 1.2 0.1 0.3 0.4 0.1 1.1 0.3 RIMBP2 "KIAA0318, MGC15831, PPP1R133, RBP2, RIM-BP2" ENSG00000060709 "RIMS binding protein 2" O15034 12 130396137-130716281 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 25.9;parathyroid gland: 24.6;pituitary gland: 32.2" "Group enriched" "Detected in some" 4 "Enteroendocrine cells: 75.5;Excitatory neurons: 128.2;Inhibitory neurons: 191.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "SCLC-21H: 28.9;SH-SY5Y: 55.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041494, HPA044114" Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Golgi apparatus, Cytosol" "HPA041494: , HPA044114: AB_2678815" "unprognostic (4.15e-4)" "unprognostic (9.77e-3)" "unprognostic (1.20e-1)" "unprognostic (6.45e-2)" "unprognostic (1.91e-3)" "unprognostic (3.63e-1)" "unprognostic (1.32e-2)" "unprognostic (1.76e-1)" "unprognostic (1.47e-1)" "unprognostic (6.82e-3)" "prognostic favorable (4.16e-4)" "unprognostic (2.86e-1)" "unprognostic (6.41e-3)" "unprognostic (5.27e-2)" "unprognostic (2.07e-1)" "unprognostic (1.03e-1)" "unprognostic (4.73e-2)" 0.6 14.5 6.3 0.9 11.3 0.2 0.2 0.0 17.5 7.2 17.3 1.5 2.9 2.7 2.5 0.5 7.8 0.9 0.0 25.9 19.2 5.9 0.2 0.4 0.1 1.7 19.6 2.1 2.5 24.6 32.2 0.0 20.6 1.1 1.8 11.2 0.3 1.3 0.2 2.7 2.5 2.4 0.1 1.0 5.9 2.6 0.9 0.3 0.6 3.9 0.1 0.3 0.6 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 5.5 0.0 0.0 0.0 0.4 7.3 0.0 0.0 28.9 55.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 11.3 0.0 17.5 25.9 19.2 1.7 19.6 20.6 0.1 0.9 2.7 0.4 0.0 0.0 5.9 0.0 2.0 0.1 0.0 0.6 19.4 0.0 0.1 1.4 0.0 0.0 0.0 31.3 0.0 0.0 0.4 0.0 0.0 3.8 3.0 1.4 0.4 75.5 0.0 128.2 0.0 0.0 0.7 4.1 6.4 0.0 0.0 0.0 0.0 0.0 10.1 191.4 2.6 6.1 0.0 0.5 2.1 0.9 0.0 0.0 1.0 0.0 3.2 0.0 19.6 5.3 0.1 0.1 0.7 0.0 0.1 0.0 0.1 0.7 14.0 0.0 0.0 0.2 1.7 1.5 0.1 0.6 0.0 0.1 0.0 0.8 0.0 RNASE2 "EDN, RAF3, RNS2" ENSG00000169385 "Ribonuclease A family member 2" P10153 14 20955487-20956436 "Enzymes, Plasma proteins, Predicted secreted proteins" Chemotaxis "Endonuclease, Hydrolase, Lyase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 49 "bone marrow: 1713.7" "Cell type enhanced" "Detected in some" "Erythroid cells: 30.7;Kupffer cells: 174.3;Macrophages: 82.2;monocytes: 54.6" "Cancer enriched" "Detected in many" 7 "glioma: 14.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 457.5;eosinophil: 1352.6" "Lineage enriched" "Detected in many" 7 "granulocytes: 1352.6" "Group enriched" "Detected in some" 303 "HL-60: 539.0;NB-4: 539.8;THP-1: 1405.4;U-937: 1295.9" HPA044983 Enhanced "Secreted to blood" NA NA 200000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA044983: AB_10963689" "unprognostic (6.66e-2)" "unprognostic (3.00e-1)" "unprognostic (6.85e-2)" "unprognostic (7.68e-2)" "unprognostic (2.73e-2)" "unprognostic (9.26e-2)" "unprognostic (4.94e-3)" "unprognostic (6.77e-2)" "unprognostic (9.54e-2)" "unprognostic (3.24e-2)" "unprognostic (3.25e-2)" "unprognostic (3.45e-1)" "prognostic unfavorable (3.28e-13)" "unprognostic (2.27e-2)" "unprognostic (7.14e-3)" "unprognostic (5.33e-2)" "unprognostic (1.50e-1)" 7.1 6.0 3.0 9.1 2.8 1713.7 1.7 2.9 5.5 2.3 4.4 2.2 0.2 2.1 0.3 0.9 5.7 2.6 4.0 2.8 4.2 1.7 4.6 12.2 1.9 5.4 4.1 1.5 1.7 0.5 1.7 1.8 4.4 1.7 0.7 1.7 1.9 0.2 0.7 2.9 1.4 9.7 4.5 35.1 2.1 0.7 4.2 14.8 0.9 0.6 0.6 5.2 1.4 6.3 1.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 3.1 0.0 539.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 539.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.3 0.0 0.0 1405.4 0.0 0.0 0.1 0.0 1.2 0.0 0.2 0.7 0.0 1295.9 0.0 457.5 109.0 1352.6 0.4 19.3 0.8 0.3 0.4 0.0 191.8 0.4 0.4 0.4 9.8 0.1 2.8 2.6 0.1 39.9 3.0 2.8 2.9 5.5 2.8 4.2 5.4 4.1 4.4 4.5 4.2 6.3 0.2 3.2 0.5 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.1 1.4 0.0 1.9 0.0 0.5 0.0 0.0 1.3 0.0 30.7 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 1.4 2.2 13.0 0.0 0.0 0.0 0.0 174.3 0.7 1.7 0.3 82.2 0.0 0.0 54.6 0.1 2.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 19.7 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.5 0.0 0.0 0.0 RNASEH2A "AGS4, RNASEHI, RNHIA, RNHL" ENSG00000104889 "Ribonuclease H2 subunit A" O75792 19 12806584-12813640 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease" "Aicardi-Goutieres syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 62.3;Extravillous trophoblasts: 117.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042692 Enhanced Nucleoplasm,Cytosol No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "HPA042692: AB_10793981" "unprognostic (6.74e-2)" "prognostic favorable (1.18e-4)" "prognostic favorable (6.18e-4)" "unprognostic (2.24e-1)" "unprognostic (2.62e-1)" "unprognostic (5.13e-2)" "prognostic unfavorable (8.72e-5)" "unprognostic (8.48e-2)" "unprognostic (9.33e-2)" "prognostic favorable (1.22e-4)" "unprognostic (3.80e-3)" "unprognostic (8.71e-2)" "prognostic unfavorable (6.29e-6)" "unprognostic (3.40e-3)" "unprognostic (4.35e-2)" "unprognostic (5.35e-2)" "unprognostic (8.60e-2)" 8.9 6.8 7.0 11.8 7.2 28.0 9.0 10.4 9.1 10.8 6.2 10.5 10.3 8.5 4.9 18.3 10.6 4.9 7.6 7.2 6.1 7.4 6.9 7.3 17.1 7.3 6.5 8.9 9.2 5.3 5.4 10.4 7.4 6.0 10.7 8.4 8.6 5.0 8.9 13.9 10.0 8.2 6.0 14.5 9.4 19.8 6.8 24.4 7.5 6.6 18.7 8.2 10.8 9.5 130.0 103.8 94.8 75.7 12.3 23.4 76.2 68.4 40.0 126.3 136.0 76.2 58.7 126.9 106.2 36.6 59.6 79.4 82.6 89.2 83.5 82.7 118.1 67.7 112.9 89.9 7.1 70.6 60.5 10.4 19.7 110.7 43.9 21.4 47.3 114.8 91.2 46.8 82.0 251.4 132.8 83.0 56.4 79.1 167.4 146.1 102.0 113.7 39.6 63.8 119.8 76.7 67.0 39.8 46.7 39.8 76.1 78.4 29.3 129.2 55.7 197.0 126.1 97.6 130.3 108.5 77.4 129.4 105.5 9.4 19.1 17.2 23.9 27.6 23.3 36.8 19.6 22.5 19.0 36.3 15.9 19.6 4.4 44.8 27.7 21.0 25.8 19.1 7.0 7.2 10.4 9.1 7.2 6.1 7.3 6.5 7.4 6.0 6.8 9.5 5.3 0.0 2.6 1.3 15.3 14.0 15.7 22.9 6.8 16.2 2.8 11.7 2.7 12.8 7.6 0.0 4.2 62.3 9.1 11.3 0.0 5.4 16.1 0.8 1.6 9.0 8.4 38.7 2.2 6.0 117.4 10.3 10.7 1.1 3.8 2.5 11.7 4.4 48.9 8.4 3.0 13.9 22.4 9.1 13.2 18.8 8.4 9.3 12.4 1.9 8.5 10.4 14.4 1.0 2.4 2.1 6.8 4.9 33.0 5.3 6.2 1.0 9.5 13.9 6.6 15.6 9.8 51.2 44.9 23.8 13.2 22.7 10.2 0.8 24.8 16.1 RNF223 ENSG00000237330 "Ring finger protein 223" E7ERA6 1 1070967-1074306 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "cervix: 10.6;esophagus: 26.2;vagina: 13.0" "Cell type enhanced" "Detected in many" "Breast glandular cells: 29.1;Endometrial ciliated cells: 30.9;Extravillous trophoblasts: 19.3;Gastric mucus-secreting cells: 38.2;Glandular and luminal cells: 32.1;Urothelial cells: 32.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 15.4;CAPAN-2: 11.1;HaCaT: 7.0;MCF7: 24.4;OE19: 7.0;SK-BR-3: 16.0;T-47d: 10.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 35: Glandular cells - Unknown function" "unprognostic (4.71e-1)" "unprognostic (2.79e-1)" "unprognostic (1.06e-1)" "prognostic favorable (8.08e-5)" "unprognostic (3.50e-1)" "unprognostic (6.50e-2)" "unprognostic (1.43e-3)" "unprognostic (3.91e-1)" "unprognostic (5.09e-2)" "prognostic unfavorable (6.53e-4)" "unprognostic (1.16e-1)" "unprognostic (4.06e-3)" "unprognostic (1.50e-1)" "unprognostic (1.16e-1)" "unprognostic (4.58e-1)" "unprognostic (9.52e-3)" 0.0 0.0 0.3 0.0 0.4 0.2 0.4 1.2 0.5 10.6 0.0 1.1 0.1 0.3 0.0 26.2 0.0 0.0 0.0 0.1 0.3 0.9 0.0 0.4 0.0 0.8 0.3 0.0 0.1 0.0 0.0 0.6 1.0 0.4 0.3 0.2 4.1 0.0 0.0 3.3 0.0 0.0 0.0 0.0 3.8 0.1 0.3 0.0 0.0 0.0 0.9 3.4 13.0 0.6 15.4 0.0 0.0 0.1 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.5 11.1 0.0 0.1 0.0 0.1 7.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 24.4 0.0 0.1 0.0 7.0 0.3 0.0 0.0 0.4 0.0 1.4 0.0 0.0 0.2 16.0 0.3 0.1 10.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.4 1.2 0.5 0.1 0.3 0.8 0.3 1.0 0.0 0.3 0.6 0.1 9.6 0.0 0.0 0.1 0.5 8.8 1.3 0.0 0.0 29.1 10.8 0.6 0.0 2.3 1.8 0.0 0.8 0.4 15.6 0.0 7.3 0.0 30.9 3.0 0.5 0.0 0.0 0.0 3.1 19.3 0.3 38.2 32.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 9.7 2.0 0.0 0.0 0.0 0.0 0.4 1.8 0.0 0.0 0.0 0.0 0.0 0.0 15.6 8.1 0.0 0.0 7.0 0.9 0.1 3.8 0.0 0.0 0.2 0.5 0.0 0.0 11.7 1.4 5.1 0.3 0.0 5.2 32.8 RRM2 "C2orf48, FLJ25102" ENSG00000171848 "Ribonucleotide reductase regulatory subunit M2" P31350 2 10120698-10211725 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "DNA replication" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 44.2;esophagus: 18.4;intestine: 19.7;lymphoid tissue: 58.1" "Group enriched" "Detected in many" 4 "Erythroid cells: 214.0;Extravillous trophoblasts: 254.1;Plasma cells: 248.0" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056994 Enhanced Supported Cytosol Yes Yes 13000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA056994: AB_2683304" "unprognostic (2.10e-2)" "unprognostic (1.62e-1)" "unprognostic (6.40e-3)" "unprognostic (4.42e-3)" "unprognostic (5.70e-2)" "unprognostic (1.69e-1)" "prognostic unfavorable (1.39e-5)" "unprognostic (1.04e-3)" "unprognostic (6.67e-3)" "unprognostic (4.53e-2)" "prognostic unfavorable (1.62e-4)" "unprognostic (5.11e-3)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.05e-2)" "unprognostic (2.24e-1)" "unprognostic (1.38e-1)" "unprognostic (2.09e-2)" 1.5 1.3 0.3 12.4 0.3 44.2 2.9 0.5 0.4 3.0 1.9 14.2 9.4 2.2 0.7 18.4 0.8 1.1 0.5 0.3 0.3 0.9 3.2 2.4 35.5 0.4 0.4 0.3 1.1 0.3 0.2 4.6 0.4 0.9 19.7 0.2 2.1 0.5 0.1 3.7 7.5 6.1 0.3 11.1 6.0 2.9 0.8 58.1 0.9 0.1 37.6 6.0 4.6 0.5 110.2 25.0 127.1 49.9 7.4 22.5 116.8 209.2 128.6 170.2 187.9 70.8 59.1 114.4 9.5 88.6 151.1 55.0 188.0 136.6 198.0 210.7 41.8 146.3 52.1 105.1 0.8 146.7 87.4 8.1 3.4 234.6 16.2 27.7 103.3 110.4 63.4 328.6 214.3 57.1 167.3 90.9 83.0 133.3 103.6 87.6 187.0 67.8 87.1 62.7 67.7 56.2 198.0 116.6 17.3 51.8 69.2 31.4 57.6 93.1 125.1 66.9 289.6 212.1 184.9 195.9 51.0 134.4 107.7 0.3 0.1 0.1 1.2 0.0 0.0 0.1 0.3 0.8 0.1 0.1 0.1 0.4 0.4 0.8 0.0 0.1 0.2 0.2 0.3 0.3 0.5 0.4 0.3 0.3 0.4 0.4 0.4 0.3 0.8 0.5 0.2 3.2 1.5 0.0 25.0 10.5 3.0 9.2 1.2 0.0 3.9 4.4 1.4 1.5 2.3 0.0 0.0 42.3 5.6 12.9 1.9 1.2 3.9 2.2 3.5 4.2 0.0 214.0 0.1 0.0 254.1 11.2 11.7 3.6 5.7 12.2 3.9 3.7 47.9 0.0 0.0 26.9 2.0 7.2 8.8 6.8 0.3 5.0 0.0 1.0 0.0 0.0 7.2 0.0 0.0 0.5 0.3 0.4 248.0 1.5 2.4 2.1 4.6 0.0 0.0 0.2 14.6 22.9 34.0 51.5 1.6 48.7 11.9 1.2 36.7 5.6 S100P ENSG00000163993 "S100 calcium binding protein P" P25815 4 6693878-6697170 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 1410.7;stomach 1: 1742.0;urinary bladder: 1777.0" "Cell type enhanced" "Detected in many" "Club cells: 1088.3;Gastric mucus-secreting cells: 2306.9;Syncytiotrophoblasts: 2773.6;Urothelial cells: 4448.3" "Cancer enhanced" "Detected in many" "urothelial cancer: 564.7" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 46 "basophil: 1789.3;eosinophil: 836.9;neutrophil: 2961.8" "Lineage enriched" "Detected in many" 73 "granulocytes: 2961.8" "Cell line enhanced" "Detected in many" "BEWO: 879.0;Hep G2: 1283.2;hTCEpi: 1185.6;OE19: 4335.4;RT4: 2619.8;SK-BR-3: 1057.4" "HPA019502, HPA075251" Enhanced Supported Nucleoplasm NA NA 1600000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 21: OE19 - Mitochondria" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm "HPA019502: AB_1856530, HPA075251: " "unprognostic (1.46e-1)" "unprognostic (1.50e-1)" "unprognostic (7.52e-2)" "unprognostic (1.44e-1)" "unprognostic (2.22e-1)" "unprognostic (7.34e-2)" "unprognostic (1.60e-3)" "unprognostic (3.92e-2)" "unprognostic (7.19e-2)" "unprognostic (9.24e-2)" "prognostic unfavorable (2.00e-4)" "unprognostic (3.87e-2)" "unprognostic (1.96e-2)" "unprognostic (1.72e-1)" "unprognostic (9.24e-2)" "unprognostic (3.65e-1)" "unprognostic (1.12e-2)" 14.0 1.7 1.0 42.4 1.4 1410.7 7.4 1.6 6.3 15.0 1.4 155.6 13.2 5.9 0.0 340.6 6.9 52.1 2.7 1.4 0.9 2.1 8.8 14.7 1.0 1.1 1.1 0.5 4.7 0.4 1.7 474.7 3.2 25.5 176.0 0.1 8.2 0.5 0.4 20.9 23.8 16.6 0.6 34.3 1742.0 1.4 1.0 10.6 0.6 12.2 96.9 1777.0 34.5 1.1 115.2 89.1 0.0 0.1 0.0 0.5 879.0 0.0 1.0 0.0 0.0 5.2 17.6 0.7 40.1 0.6 1.2 137.6 0.5 1.1 0.0 54.7 0.0 1.9 106.7 1283.2 0.0 53.4 3.2 0.6 1185.6 0.0 1.1 0.2 0.2 0.8 3.1 0.0 0.0 214.5 1.6 126.5 1.5 4335.4 149.6 0.9 0.5 0.5 0.0 2619.8 1.1 0.7 156.8 1057.4 2.4 39.9 31.0 169.6 0.5 0.0 1.4 0.2 0.9 1.2 0.7 0.8 0.1 479.1 0.2 1789.3 40.6 836.9 1.4 9.5 1.1 0.4 1.7 1.1 1.6 0.5 0.3 0.8 2961.8 0.1 5.7 0.4 1.1 16.7 1.0 1.4 1.6 6.3 1.4 0.9 1.1 1.1 3.2 0.6 1.0 1.1 0.9 9.6 48.6 0.0 6.2 1.1 318.3 568.6 4.0 0.0 3.4 3.6 1.2 27.1 1088.3 1.8 0.0 550.7 2.2 322.2 0.0 4.8 12.3 37.5 38.9 8.7 16.6 0.0 0.0 31.1 783.4 13.8 2306.9 202.5 31.6 0.0 1.4 7.4 69.2 0.0 0.0 443.7 152.5 11.8 1.0 7.4 0.0 11.0 8.8 0.0 5.6 0.0 2.1 0.0 0.1 828.1 580.9 0.0 5.9 288.4 2.2 0.5 301.5 0.0 0.0 0.1 32.1 0.5 0.6 18.6 6.3 2773.6 9.8 0.1 173.2 4448.3 S1PR1 "CD363, D1S3362, edg-1, EDG1" ENSG00000170989 "Sphingosine-1-phosphate receptor 1" P21453 1 101236865-101243713 "Cancer-related genes, CD markers, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "Angiogenesis, Chemotaxis" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 236.1;Endothelial cells: 122.3;Hepatic stellate cells: 114.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 1248.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ: 73.0;HUVEC TERT2: 198.9;TIME: 113.3;U-251 MG: 147.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010104, HPA075568" Supported Supported Vesicles No NA "Cluster 38: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "CAB010104: AB_2238920, HPA075568: AB_2686758" "unprognostic (1.41e-1)" "unprognostic (9.35e-2)" "unprognostic (2.46e-2)" "unprognostic (2.61e-1)" "unprognostic (9.78e-2)" "unprognostic (4.49e-3)" "unprognostic (1.34e-3)" "unprognostic (1.99e-1)" "unprognostic (1.36e-1)" "unprognostic (9.12e-2)" "unprognostic (2.34e-2)" "unprognostic (2.23e-1)" "unprognostic (5.82e-3)" "unprognostic (2.54e-2)" "unprognostic (1.04e-1)" "unprognostic (3.64e-1)" "prognostic unfavorable (8.78e-4)" 114.7 14.4 58.8 29.8 62.7 18.5 91.9 59.8 59.0 18.5 27.8 19.5 9.4 24.7 3.9 26.8 22.9 28.0 71.8 51.3 65.1 18.0 31.3 78.3 46.3 65.2 73.0 8.2 20.3 23.3 8.7 48.1 61.3 13.7 10.1 14.6 15.0 7.8 27.9 17.9 22.3 31.2 57.6 63.1 17.1 2.6 76.5 21.4 35.9 51.5 26.9 34.3 19.2 52.6 15.6 0.2 14.2 0.0 1.4 32.7 0.1 73.0 13.5 47.9 16.6 0.1 0.7 0.0 17.8 25.2 0.4 0.0 1.8 0.8 27.0 6.1 1.2 6.8 0.3 0.0 6.6 0.0 3.5 45.0 0.3 0.1 3.7 1.7 198.9 5.8 0.2 14.4 13.5 0.0 20.6 0.0 3.9 0.4 4.8 0.0 13.4 0.5 0.1 0.0 0.0 0.1 0.7 0.0 0.2 0.9 0.0 0.2 113.3 6.8 2.9 2.0 147.1 1.3 0.0 1.0 0.7 0.0 0.4 1248.4 2.2 55.4 589.4 2.1 441.5 294.7 502.6 492.1 2.6 346.9 383.3 396.3 15.4 397.5 3.4 3.1 329.4 438.7 58.8 62.7 59.8 59.0 51.3 65.1 65.2 73.0 61.3 57.6 76.5 52.6 236.1 0.0 8.9 37.9 36.0 7.6 0.2 0.0 2.2 0.4 1.1 1.1 23.8 2.8 1.3 0.0 0.0 5.9 25.0 0.0 0.0 0.0 0.0 1.1 1.0 122.3 0.0 0.4 0.1 0.0 0.3 11.7 0.5 1.8 7.6 9.7 114.2 8.9 9.9 0.0 0.3 0.0 0.0 6.5 5.7 0.0 0.9 3.0 5.4 13.1 9.9 31.1 40.2 0.5 0.2 0.0 0.0 0.0 18.2 0.5 0.0 0.1 0.0 1.4 0.0 3.6 4.8 0.7 0.7 0.6 5.1 2.6 29.9 1.8 0.1 0.4 SCIMP "C17orf87, DTFT5783, FLJ32580, MGC163426, MGC163428, UNQ5783" ENSG00000161929 "SLP adaptor and CSK interacting membrane protein" Q6UWF3 17 5208920-5234860 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 49.2" "Cell type enhanced" "Detected in many" "B-cells: 66.4;Hofbauer cells: 26.2;Kupffer cells: 120.3;Macrophages: 66.3;monocytes: 60.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in some" "cerebellum: 2.7" "Group enriched" "Detected in many" 8 "classical monocyte: 110.6;intermediate monocyte: 239.0;memory B-cell: 145.8;myeloid DC: 84.2;naive B-cell: 124.5;non-classical monocyte: 265.5" "Group enriched" "Detected in all" 9 "B-cells: 145.8;dendritic cells: 84.2;monocytes: 265.5" "Cell line enhanced" "Detected in many" "HeLa: 6.8;U-698: 10.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA006117 Enhanced NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA006117: AB_1858633" "unprognostic (2.53e-2)" "unprognostic (7.88e-3)" "unprognostic (1.26e-2)" "unprognostic (5.79e-3)" "unprognostic (1.10e-1)" "unprognostic (3.87e-2)" "unprognostic (7.96e-2)" "unprognostic (1.73e-2)" "unprognostic (4.93e-2)" "unprognostic (2.99e-1)" "unprognostic (1.35e-1)" "unprognostic (8.05e-2)" "unprognostic (3.33e-2)" "unprognostic (2.07e-1)" "unprognostic (4.42e-2)" "unprognostic (1.77e-1)" "unprognostic (9.95e-2)" 5.9 4.1 0.0 30.4 0.1 5.1 1.4 2.7 1.3 1.5 3.6 4.5 5.4 2.9 1.1 1.9 3.1 7.3 1.7 0.3 0.0 2.3 10.6 16.2 39.4 0.6 0.1 3.6 3.9 0.8 0.7 3.9 0.1 3.1 4.6 7.5 4.0 1.4 4.3 3.2 10.2 6.1 0.0 49.2 5.0 2.8 0.0 5.1 3.4 0.8 44.9 6.0 0.6 0.4 1.0 1.5 2.5 3.3 0.0 0.0 2.5 1.1 0.0 0.0 0.0 0.7 2.1 4.8 0.9 0.0 1.8 1.0 0.0 0.0 0.0 0.8 2.1 2.0 6.8 0.7 0.0 0.2 0.7 0.0 0.1 0.0 0.2 1.2 0.0 4.2 0.1 1.2 0.0 1.6 2.4 0.7 1.1 0.3 1.4 2.2 0.5 0.5 0.0 0.6 1.8 0.8 1.8 0.6 1.3 0.7 2.6 2.4 0.3 0.3 1.1 1.4 0.6 0.7 0.3 10.8 1.2 0.3 0.7 16.8 110.6 3.0 1.3 239.0 1.5 145.8 0.8 1.2 84.2 124.5 1.7 1.2 19.0 5.3 265.5 3.2 1.4 68.0 0.0 0.1 2.7 1.3 0.3 0.0 0.6 0.1 0.1 0.0 0.0 0.4 0.5 0.0 4.4 2.6 66.4 0.4 0.4 0.0 0.0 2.5 0.4 0.5 0.4 1.5 0.6 0.0 12.5 0.3 1.5 0.0 0.0 0.7 1.4 0.4 0.3 2.0 0.0 0.4 6.5 0.9 0.3 0.6 0.0 0.1 1.3 0.4 3.3 1.9 26.2 1.7 4.9 0.0 0.0 120.3 4.2 0.7 0.3 66.3 0.0 8.4 60.3 0.4 10.3 4.0 2.3 0.4 0.0 0.4 1.7 0.3 0.0 1.0 1.6 4.1 0.0 0.7 0.3 0.5 0.8 0.0 0.4 0.1 3.2 0.2 0.0 0.4 SHCBP1 "FLJ22009, PAL" ENSG00000171241 "SHC binding and spindle associated 1" Q8NEM2 16 46578591-46621379 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 17.4;lymphoid tissue: 10.6" "Cell type enhanced" "Detected in many" "Erythroid cells: 36.2;Extravillous trophoblasts: 28.7;Plasma cells: 38.3;Spermatocytes: 33.7;Spermatogonia: 23.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA048876 Uncertain Approved "Nuclear bodies,Microtubules,Midbody,Mitotic spindle" Yes Yes "Cluster 19: B-cells - Humoral immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear bodies" "Microtubules, Midbody, Mitotic spindle" "HPA048876: AB_2680542" "unprognostic (2.44e-3)" "unprognostic (1.13e-1)" "unprognostic (2.98e-2)" "unprognostic (2.74e-1)" "unprognostic (2.54e-2)" "unprognostic (2.35e-2)" "unprognostic (2.96e-4)" "unprognostic (2.26e-3)" "unprognostic (5.35e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (4.47e-5)" "unprognostic (4.81e-2)" "unprognostic (2.22e-16)" "unprognostic (3.59e-2)" "unprognostic (3.86e-2)" "unprognostic (2.66e-1)" "unprognostic (2.66e-1)" 0.7 0.5 0.5 5.1 0.5 17.4 0.9 1.2 0.6 0.6 0.4 1.9 1.2 0.6 0.6 3.5 0.2 0.6 1.0 0.4 0.2 5.4 0.2 1.0 9.8 0.4 0.3 0.3 0.2 0.2 0.2 2.4 0.4 0.3 2.2 0.2 0.8 0.2 1.5 3.3 1.5 1.7 0.1 4.4 0.9 5.2 0.5 8.8 0.3 0.2 10.6 1.2 1.2 0.7 33.8 30.8 11.9 15.3 3.1 6.2 16.2 60.7 24.6 59.2 26.8 14.6 20.8 28.0 30.2 28.8 26.8 21.0 29.3 21.7 73.8 17.7 17.2 28.2 25.8 30.3 0.1 28.5 35.4 1.2 1.6 45.9 18.1 5.9 33.0 14.9 12.7 28.3 69.7 21.5 24.0 23.7 10.0 17.2 31.6 45.4 89.9 44.8 13.7 9.4 5.0 7.2 46.0 23.7 11.1 11.4 13.0 23.4 16.1 43.9 28.7 43.5 54.0 24.9 36.7 46.7 21.4 31.3 45.8 0.2 0.3 0.6 0.2 0.5 0.0 1.7 0.3 0.1 0.3 1.2 0.0 0.1 0.4 0.1 2.4 0.7 1.2 1.1 0.5 0.5 1.2 0.6 0.4 0.2 0.4 0.3 0.4 0.1 0.5 0.7 0.2 0.0 1.1 1.3 7.1 1.7 0.7 1.2 0.0 0.3 0.6 1.1 1.9 1.5 1.4 0.0 0.0 11.3 0.8 1.9 0.0 0.2 8.4 0.7 1.7 1.7 0.0 36.2 2.1 0.0 28.7 3.7 4.1 1.5 0.0 7.6 1.8 0.3 12.6 0.0 0.7 2.2 2.0 4.5 3.3 2.3 0.6 4.0 1.8 2.8 2.8 0.8 0.0 1.0 0.5 0.1 0.1 0.4 38.3 0.5 0.4 0.1 0.1 0.3 0.0 0.5 6.3 33.7 23.7 3.6 0.6 3.7 2.2 0.8 3.4 1.1 SIGLEC11 ENSG00000161640 "Sialic acid binding Ig like lectin 11" Q96RL6 19 49948985-49961172 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "lymphoid tissue: 23.1;ovary: 65.5" "Group enriched" "Detected in some" 7 "Granulosa cells: 196.9;Theca cells: 192.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "eosinophil: 1.4;non-classical monocyte: 1.3" "Group enriched" "Detected in many" 6 "granulocytes: 1.4;monocytes: 1.3" "Cell line enriched" "Detected in single" 16 "HEL: 10.1" "HPA052132, HPA060278" Approved Uncertain "Nucleoplasm,Golgi apparatus" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 36: HEL - Hemostasis" "Cluster 40: Granulosa cells - Unknown function" "Golgi apparatus" Nucleoplasm "HPA052132: , HPA060278: AB_2684240" "unprognostic (1.07e-1)" "unprognostic (2.85e-3)" "unprognostic (1.56e-1)" "unprognostic (1.31e-1)" "unprognostic (1.09e-1)" "unprognostic (3.35e-2)" "unprognostic (9.93e-2)" "unprognostic (8.88e-2)" "unprognostic (1.27e-1)" "unprognostic (2.06e-1)" "unprognostic (3.63e-1)" "unprognostic (1.20e-1)" "unprognostic (8.79e-4)" "unprognostic (2.11e-1)" "unprognostic (1.41e-1)" "unprognostic (9.95e-3)" "unprognostic (5.38e-2)" 1.1 7.3 0.5 1.8 0.8 0.4 0.4 0.4 0.7 0.3 0.6 0.5 0.8 0.3 0.2 0.1 0.9 0.3 0.4 0.6 0.6 0.4 1.7 1.7 0.6 1.4 1.0 65.5 2.7 0.1 0.2 1.8 1.3 0.2 0.4 0.2 0.3 0.2 0.2 0.2 1.0 1.2 0.8 23.1 4.7 1.5 1.6 0.1 0.2 0.1 0.0 0.6 0.2 1.4 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 10.1 0.1 0.1 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.3 1.4 0.0 1.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.2 1.3 0.1 0.0 0.1 0.5 0.8 0.4 0.7 0.6 0.6 1.4 1.0 1.3 0.8 1.6 1.4 0.1 0.0 1.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 19.6 0.0 0.6 0.2 0.3 1.0 0.0 0.0 0.0 1.1 0.1 4.3 0.0 0.3 0.0 196.9 5.3 0.6 7.9 0.0 0.0 0.0 0.0 26.8 0.2 0.1 0.0 6.1 0.0 5.6 1.3 0.0 0.0 0.0 0.0 2.7 0.0 0.4 0.0 0.2 0.0 0.1 0.0 0.0 0.0 1.2 7.5 1.7 0.7 0.0 0.1 0.1 0.2 192.3 0.0 0.0 SIGLEC14 ENSG00000254415 "Sialic acid binding Ig like lectin 14" Q08ET2 19 51642553-51646801 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 28.3;lymphoid tissue: 40.3" "Cell type enhanced" "Detected in some" "Hofbauer cells: 18.5;Kupffer cells: 41.5;Macrophages: 13.5;monocytes: 24.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 109.1;intermediate monocyte: 125.1;myeloid DC: 65.4;neutrophil: 200.1;non-classical monocyte: 93.3" "Group enriched" "Detected in many" 7 "dendritic cells: 65.4;granulocytes: 200.1;monocytes: 125.1" "Group enriched" "Detected in some" 11 "HMC-1: 98.7;U-937: 24.7" "HPA014377, HPA014428" Uncertain Uncertain "Vesicles,Plasma membrane" NA NA 24000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "Plasma membrane" "HPA014377: AB_2189277, HPA014428: " "unprognostic (3.05e-1)" "unprognostic (1.75e-1)" "unprognostic (6.47e-3)" "unprognostic (1.60e-1)" "unprognostic (3.83e-2)" "unprognostic (1.50e-2)" "unprognostic (1.44e-1)" "unprognostic (1.46e-1)" "unprognostic (9.77e-3)" "unprognostic (9.28e-2)" "unprognostic (6.73e-2)" "unprognostic (1.02e-1)" "unprognostic (4.28e-3)" "unprognostic (8.38e-2)" "unprognostic (4.17e-2)" "unprognostic (1.34e-1)" "unprognostic (1.89e-1)" 3.4 2.4 1.4 25.2 1.5 28.3 1.0 1.6 3.2 1.8 1.3 1.8 0.7 0.9 0.3 1.1 2.3 2.6 1.3 1.4 2.4 0.7 3.5 7.3 13.3 4.7 3.0 0.4 1.1 0.4 0.5 2.5 3.9 0.9 1.6 0.1 1.1 0.9 0.4 0.3 6.1 2.5 2.7 40.3 1.6 2.4 3.9 1.9 0.6 0.0 14.2 4.1 0.6 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 1.6 98.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 24.7 0.0 16.6 109.1 1.8 0.3 125.1 0.1 19.3 0.2 0.3 65.4 18.2 0.1 0.1 200.1 0.7 93.3 12.0 0.2 40.3 1.4 1.5 1.6 3.2 1.4 2.4 4.7 3.0 3.9 2.7 3.9 4.1 0.0 0.0 1.1 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 6.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.4 18.5 0.0 0.0 0.0 0.0 41.5 6.0 0.8 0.3 13.5 0.0 1.0 24.1 0.0 2.1 0.0 0.0 0.0 0.0 2.6 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.0 SIGLEC7 "CD328, p75/AIRM1, QA79, SIGLEC-7, SIGLEC19P, SIGLECP2" ENSG00000168995 "Sialic acid binding Ig like lectin 7" Q9Y286 19 51142299-51153526 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 19.2" "Cell type enhanced" "Detected in some" "Hofbauer cells: 31.3;Kupffer cells: 57.4;Macrophages: 33.1;monocytes: 15.5;NK-cells: 69.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 242.1" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 9 "Karpas-707: 55.4;RPMI-8226: 33.7;U-937: 35.0" HPA075513 Approved "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 2600000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" Vesicles "HPA075513: " "unprognostic (3.14e-1)" "unprognostic (5.87e-2)" "unprognostic (1.03e-1)" "unprognostic (2.66e-1)" "unprognostic (3.90e-2)" "unprognostic (1.85e-1)" "unprognostic (2.53e-1)" "unprognostic (2.78e-1)" "unprognostic (1.69e-1)" "unprognostic (4.95e-2)" "unprognostic (1.10e-1)" "unprognostic (2.66e-1)" "unprognostic (8.27e-2)" "unprognostic (6.61e-2)" "unprognostic (1.14e-3)" "unprognostic (2.58e-1)" "unprognostic (2.26e-2)" 3.7 2.9 0.9 10.6 1.0 4.6 1.0 1.0 1.9 0.6 1.2 1.9 1.6 0.5 0.4 0.4 1.2 2.6 1.3 0.8 1.3 1.6 7.4 5.0 7.7 2.1 1.5 0.4 0.5 0.7 0.6 6.2 1.9 0.7 2.4 0.2 0.7 0.4 0.2 0.2 2.2 3.8 1.4 19.2 0.9 0.9 2.2 1.5 0.5 0.3 2.4 3.1 0.5 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.4 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.1 33.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.1 0.0 1.2 1.1 0.0 0.2 35.0 0.0 3.2 140.2 242.1 10.6 105.8 18.9 3.8 0.2 4.8 65.5 0.2 0.3 4.4 116.7 96.8 44.0 2.9 0.0 80.9 0.9 1.0 1.0 1.9 0.8 1.3 2.1 1.5 1.9 1.4 2.2 2.4 0.4 0.0 2.2 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 1.8 0.0 0.2 8.3 0.1 0.0 0.0 0.4 0.0 0.2 0.6 0.0 8.8 0.0 0.0 0.2 0.3 0.0 0.0 1.3 0.0 6.1 0.8 31.3 0.0 0.0 0.0 0.0 57.4 3.5 0.0 1.5 33.1 0.0 0.0 15.5 0.0 69.0 0.0 0.0 0.1 0.0 1.2 0.1 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 3.5 0.4 0.0 0.0 SIGLEC9 CD329 ENSG00000129450 "Sialic acid binding Ig like lectin 9" Q9Y336 19 51124906-51136651 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 20.7" "Cell type enhanced" "Detected in some" "Hofbauer cells: 42.1;Kupffer cells: 39.8;Langerhans cells: 13.4;Macrophages: 26.8;monocytes: 10.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "classical monocyte: 198.9;intermediate monocyte: 182.5;myeloid DC: 169.1;neutrophil: 212.0;non-classical monocyte: 121.9" "Group enriched" "Detected in many" 13 "dendritic cells: 169.1;granulocytes: 212.0;monocytes: 198.9" "Group enriched" "Detected in some" 10 "Karpas-707: 23.4;RPMI-8226: 16.5" HPA010682 Uncertain NA NA 270000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" "HPA010682: AB_1079968" "unprognostic (2.31e-1)" "unprognostic (3.99e-2)" "unprognostic (1.03e-2)" "unprognostic (1.36e-1)" "unprognostic (4.69e-2)" "unprognostic (6.86e-2)" "unprognostic (5.10e-2)" "unprognostic (2.10e-1)" "unprognostic (1.31e-1)" "unprognostic (4.73e-2)" "unprognostic (1.06e-1)" "unprognostic (7.03e-3)" "prognostic unfavorable (6.17e-5)" "unprognostic (6.56e-2)" "unprognostic (7.38e-3)" "unprognostic (2.95e-1)" "unprognostic (1.73e-1)" 8.0 5.4 2.0 17.9 2.1 9.0 1.9 2.2 4.3 1.4 2.8 2.1 1.7 0.9 0.2 0.9 2.5 5.0 2.1 1.9 3.4 1.4 5.5 8.3 5.0 5.4 4.0 3.2 1.2 4.1 0.9 7.9 5.0 1.1 2.4 0.3 1.5 0.9 0.4 0.5 2.2 6.4 4.0 20.7 1.4 1.7 6.2 1.4 0.9 1.3 2.5 5.4 0.8 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 23.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 16.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.3 0.0 0.0 1.5 0.0 0.0 0.0 0.0 2.0 1.5 0.0 17.3 198.9 1.6 15.2 182.5 8.6 0.2 2.5 5.8 169.1 0.1 0.6 2.7 212.0 3.1 121.9 9.2 0.9 84.9 2.0 2.1 2.2 4.3 1.9 3.4 5.4 4.0 5.0 4.0 6.2 5.9 0.1 0.0 0.5 0.0 0.9 0.5 0.0 0.0 0.0 0.0 0.0 0.1 1.7 0.0 1.3 0.0 0.0 0.2 2.7 0.0 0.0 0.0 1.8 0.0 0.1 1.1 0.0 0.0 0.2 0.0 0.4 0.5 0.0 0.0 0.0 0.1 5.3 0.8 42.1 0.0 0.2 0.0 0.0 39.8 13.4 0.4 5.0 26.8 0.0 5.6 10.4 0.0 7.2 0.0 0.1 0.0 0.0 2.2 0.4 0.0 0.0 0.1 0.0 0.0 6.6 0.0 0.1 0.0 0.1 0.0 0.1 0.3 1.3 2.8 0.0 0.0 SLC26A7 SUT2 ENSG00000147606 "Solute carrier family 26 member 7" Q8TE54 8 91209494-91398155 "Metabolic proteins, Predicted membrane proteins, Transporters" "Anion exchange, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "thyroid gland: 330.3" "Cell type enhanced" "Detected in some" "Collecting duct cells: 23.9;Endometrial ciliated cells: 31.6;Endometrial stromal cells: 23.9;Enteroendocrine cells: 45.2;Glandular and luminal cells: 52.0;Hepatic stellate cells: 24.7" "Group enriched" "Detected in some" 11 "renal cancer: 8.7;thyroid cancer: 32.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 1: Thyroid gland - Transcription" "Cluster 44: Endometrium - Transcription" "unprognostic (1.63e-1)" "unprognostic (1.17e-1)" "unprognostic (5.84e-2)" "unprognostic (8.04e-3)" "unprognostic (4.15e-3)" "unprognostic (1.51e-1)" "unprognostic (2.39e-3)" "unprognostic (2.94e-3)" "unprognostic (1.24e-1)" "unprognostic (1.43e-1)" "unprognostic (1.41e-2)" "unprognostic (8.26e-2)" "unprognostic (4.82e-2)" "unprognostic (3.31e-2)" "unprognostic (2.07e-1)" "unprognostic (5.19e-3)" "unprognostic (6.83e-3)" 1.5 0.1 0.1 0.0 0.2 0.0 0.3 0.2 0.1 1.4 0.2 0.2 0.1 2.7 0.1 0.0 0.5 0.6 0.7 0.0 0.1 23.8 0.0 0.1 3.7 0.1 0.1 0.1 1.2 0.2 0.3 0.3 0.2 0.1 0.4 0.0 0.4 0.2 0.1 0.2 0.1 0.2 0.1 0.1 6.1 0.5 0.2 0.0 330.3 0.3 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.1 0.0 0.1 0.1 0.1 0.2 0.1 0.2 0.4 3.9 0.0 1.5 5.9 0.1 0.3 0.4 0.2 0.0 0.0 1.9 0.6 1.1 0.0 0.3 23.9 0.0 0.0 0.0 0.3 13.7 0.1 11.9 31.6 23.9 1.5 45.2 0.0 0.5 0.2 0.0 1.5 1.5 52.0 0.0 0.1 24.7 0.1 0.1 0.0 0.7 0.7 2.0 0.6 0.3 2.9 3.7 0.2 3.6 0.0 0.0 0.1 0.0 0.0 3.8 1.4 0.2 0.0 0.0 0.3 0.0 0.3 1.9 0.2 0.0 0.0 4.4 0.6 1.1 0.0 0.1 0.0 0.4 0.5 0.3 0.1 SLC2A12 "GLUT12, GLUT8" ENSG00000146411 "Solute carrier family 2 member 12" Q8TD20 6 133987581-134052624 "Metabolic proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 87.3" "Cell type enhanced" "Detected in many" "Astrocytes: 24.8;Oligodendrocytes: 14.5;Syncytiotrophoblasts: 36.7" "Cancer enriched" "Detected in many" 6 "prostate cancer: 18.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 7.6;hTERT-RPE1: 14.8;SuSa: 21.7;U-2 OS: 7.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031593, HPA031594" Approved Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 12: NES - Nervous system development" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane" "Cell Junctions" "HPA031593: AB_10600810, HPA031594: AB_2673948" "unprognostic (2.06e-1)" "unprognostic (1.21e-1)" "unprognostic (1.69e-2)" "unprognostic (5.55e-3)" "unprognostic (2.18e-1)" "unprognostic (6.02e-2)" "unprognostic (2.24e-3)" "unprognostic (2.54e-2)" "unprognostic (2.08e-2)" "unprognostic (3.69e-2)" "unprognostic (2.38e-1)" "unprognostic (1.83e-1)" "unprognostic (2.33e-3)" "unprognostic (3.04e-1)" "unprognostic (1.65e-1)" "unprognostic (1.04e-2)" "unprognostic (1.55e-3)" 0.5 1.0 3.6 0.3 4.8 0.0 1.1 7.8 4.6 3.0 87.3 2.1 7.3 8.2 2.1 6.1 2.8 2.6 10.7 5.7 2.6 5.8 6.8 3.1 0.1 2.3 3.1 1.2 1.1 2.3 1.4 1.6 2.5 22.4 1.0 2.3 5.1 9.3 3.8 2.7 9.8 3.1 1.6 0.1 14.3 0.4 3.4 1.0 0.2 4.1 1.2 3.5 1.2 3.1 2.5 0.9 2.3 0.0 1.4 0.7 0.1 1.5 5.4 0.7 2.9 0.0 7.6 0.3 1.2 0.1 5.7 5.9 0.0 0.5 1.0 0.0 5.3 0.0 0.8 0.1 0.2 0.0 0.0 1.0 0.5 0.6 0.1 14.8 0.4 0.4 0.5 0.8 0.1 0.8 0.1 0.1 2.0 0.0 0.5 0.0 1.0 2.2 1.6 0.8 0.2 0.7 0.1 2.1 0.0 21.7 0.1 0.0 0.1 0.2 7.6 0.2 0.9 3.2 2.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.6 4.8 7.8 4.6 5.7 2.6 2.3 3.1 2.5 1.6 3.4 3.1 0.2 0.0 7.7 24.8 0.1 2.0 1.0 3.3 8.6 0.4 0.5 2.2 6.3 0.0 2.2 0.0 0.0 2.0 0.1 1.2 3.9 1.5 0.1 3.4 0.4 2.3 4.2 0.0 8.0 0.2 0.6 2.2 2.6 1.6 0.0 0.4 0.0 1.1 0.3 0.0 3.2 0.2 6.1 0.0 0.3 0.0 0.0 0.1 0.0 4.7 0.1 9.8 0.0 4.5 14.5 1.1 2.4 1.5 1.6 10.5 0.5 0.5 10.4 0.5 0.0 2.1 1.3 0.0 0.0 8.6 1.8 36.7 0.2 3.5 0.4 1.3 SLC35F3 FLJ37712 ENSG00000183780 "Solute carrier family 35 member F3" Q8IY50 1 233904676-234324511 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 17.7" "Group enriched" "Detected in some" 6 "Excitatory neurons: 485.2;Inhibitory neurons: 216.1;Oligodendrocyte precursor cells: 190.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 35 "plasmacytoid DC: 3.5" "Lineage enriched" "Detected in single" 35 "dendritic cells: 3.5" "Cell line enriched" "Detected in some" 7 "HDLM-2: 111.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA051327, HPA061582" Uncertain Approved "Nucleoli,Golgi apparatus" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 44: HDLM-2 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus" Nucleoli "HPA051327: AB_2681443, HPA061582: AB_2684563" "unprognostic (1.11e-2)" "unprognostic (1.73e-2)" "unprognostic (2.07e-1)" "unprognostic (1.54e-1)" "unprognostic (1.26e-1)" "unprognostic (8.62e-2)" "unprognostic (2.69e-5)" "unprognostic (3.38e-2)" "unprognostic (1.94e-1)" "unprognostic (2.60e-1)" "unprognostic (3.86e-2)" "unprognostic (9.09e-2)" "unprognostic (1.57e-3)" "unprognostic (7.83e-2)" "unprognostic (2.11e-1)" "unprognostic (3.62e-1)" "unprognostic (3.58e-1)" 0.0 1.1 6.9 0.3 17.7 0.1 2.5 9.5 15.5 0.3 0.0 0.4 0.1 0.3 0.7 0.5 0.4 0.1 0.0 5.4 0.7 0.7 0.0 0.2 0.8 1.6 0.3 0.1 3.5 1.4 2.6 0.0 1.9 0.5 0.1 0.3 2.5 0.2 0.2 0.6 0.2 0.2 0.2 0.2 0.7 0.2 2.5 2.3 0.5 0.1 0.5 0.0 0.5 9.5 3.0 7.9 1.6 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.0 14.9 0.0 0.0 0.1 0.2 0.6 0.1 7.7 0.0 111.9 0.2 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 12.1 1.7 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 9.0 0.0 0.0 0.0 7.7 0.0 4.2 2.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.8 0.0 0.1 0.2 0.1 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 6.9 17.7 9.5 15.5 5.4 0.7 1.6 0.3 1.9 0.2 2.5 9.5 0.1 0.0 0.0 8.5 0.9 0.4 2.4 0.3 10.8 2.1 3.0 8.9 0.7 0.0 0.1 0.0 0.0 0.0 9.5 0.0 3.9 1.4 0.7 5.9 1.6 0.1 1.8 0.0 485.2 3.4 0.0 0.2 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 216.1 0.1 26.4 0.0 0.0 0.9 0.0 0.6 0.0 9.4 0.9 0.0 0.0 190.5 45.4 0.6 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.5 0.0 0.8 0.1 0.6 1.5 0.8 0.1 0.0 0.4 0.0 0.0 0.2 SLC7A7 "LPI, y+LAT-1" ENSG00000155465 "Solute carrier family 7 member 7" Q9UM01 14 22773222-22829820 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 131.6;kidney: 300.6" "Group enriched" "Detected in many" 4 "Hofbauer cells: 216.5;Kupffer cells: 410.6;Macrophages: 146.2;monocytes: 164.0;Proximal enterocytes: 423.1;Proximal tubular cells: 327.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 299.9;intermediate monocyte: 410.0;non-classical monocyte: 457.1" "Lineage enriched" "Detected in many" 5 "monocytes: 457.1" "Group enriched" "Detected in many" 4 "BEWO: 217.2;CACO-2: 385.7;OE19: 329.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA036227 Enhanced NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA036227: AB_10696653" "unprognostic (1.34e-1)" "unprognostic (7.65e-2)" "unprognostic (4.25e-2)" "unprognostic (2.52e-1)" "unprognostic (6.12e-2)" "unprognostic (3.69e-2)" "unprognostic (7.84e-3)" "unprognostic (1.47e-1)" "unprognostic (2.88e-2)" "unprognostic (1.73e-2)" "unprognostic (2.60e-3)" "unprognostic (7.15e-2)" "prognostic unfavorable (6.28e-6)" "unprognostic (2.68e-3)" "unprognostic (1.86e-2)" "unprognostic (2.61e-1)" "unprognostic (1.12e-1)" 15.1 9.0 3.1 37.4 3.2 19.7 6.8 3.8 7.5 7.3 4.3 13.8 107.0 5.3 2.0 3.7 7.8 17.0 5.1 2.8 3.8 300.6 16.4 54.1 29.1 6.9 4.7 2.1 5.2 78.4 1.4 18.2 6.4 3.5 15.0 1.0 5.4 2.8 2.0 3.2 131.6 15.6 5.1 56.8 8.6 32.8 7.1 9.6 4.6 2.8 25.2 14.7 4.1 8.1 0.2 11.2 1.2 0.5 1.9 3.7 217.2 2.2 16.3 0.4 1.4 385.7 34.4 17.0 72.2 1.4 1.2 13.3 0.1 0.0 0.6 0.6 0.2 0.9 0.4 3.7 9.1 1.9 1.6 7.1 1.0 1.0 0.5 1.8 25.3 1.5 0.1 12.8 2.9 0.6 0.4 1.7 3.6 329.0 0.1 2.9 35.5 9.8 0.8 1.3 0.4 0.8 0.6 0.5 2.5 9.4 0.4 8.3 1.3 0.8 1.7 0.6 0.5 2.7 0.9 8.9 0.9 0.8 0.2 0.2 299.9 1.1 0.5 410.0 0.4 19.1 0.2 0.2 99.5 13.8 0.7 0.4 36.5 0.3 457.1 3.4 0.9 155.1 3.1 3.2 3.8 7.5 2.8 3.8 6.9 4.7 6.4 5.1 7.1 8.1 5.3 12.8 7.1 2.0 14.3 1.0 0.2 6.7 1.8 0.2 0.5 1.7 0.9 67.2 5.6 3.7 0.0 1.2 5.7 3.0 11.7 8.2 61.1 1.7 1.2 5.0 1.2 0.0 0.6 6.4 5.2 4.4 2.6 0.4 1.3 0.7 16.1 3.0 216.5 0.0 1.4 7.2 2.0 410.6 16.8 11.8 3.7 146.2 5.4 20.6 164.0 0.4 4.1 0.0 0.8 8.9 12.5 0.0 20.1 0.1 423.1 327.6 9.2 1.3 6.6 0.8 1.4 17.8 2.2 0.4 0.4 1.8 2.7 38.8 6.4 0.1 SLC9A1 "APNH, NHE1, PPP1R143" ENSG00000090020 "Solute carrier family 9 member A1" P19634 1 27098809-27166981 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Transport" Calmodulin-binding "Deafness, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 76.5;stomach 1: 65.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 81.5;Gastric mucus-secreting cells: 160.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022371, HPA048532, HPA052891" Enhanced Supported "Plasma membrane" NA NA 21000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "CAB022371: , HPA048532: AB_2680431, HPA052891: AB_2681981" "unprognostic (6.18e-2)" "unprognostic (1.59e-1)" "unprognostic (2.21e-1)" "unprognostic (8.48e-2)" "prognostic unfavorable (7.47e-4)" "unprognostic (2.70e-2)" "unprognostic (4.33e-3)" "unprognostic (3.18e-2)" "unprognostic (9.74e-2)" "prognostic unfavorable (7.10e-4)" "unprognostic (3.44e-2)" "unprognostic (6.95e-2)" "unprognostic (2.05e-2)" "unprognostic (1.27e-2)" "unprognostic (1.60e-1)" "unprognostic (3.34e-1)" "unprognostic (1.16e-2)" 9.6 10.7 6.1 10.4 14.7 11.5 9.0 2.8 10.8 10.9 0.2 18.6 29.3 10.9 8.0 11.0 7.6 16.9 13.7 2.3 5.3 5.8 2.4 13.2 7.0 13.8 4.7 7.0 8.6 20.7 8.2 21.9 11.2 9.0 13.6 4.5 76.5 19.4 4.6 10.5 19.0 10.7 0.5 11.6 65.9 10.1 10.4 6.3 9.5 4.9 6.7 15.1 9.2 2.4 32.3 10.7 9.9 10.1 21.8 15.7 60.8 25.9 38.5 21.7 23.5 13.0 20.0 14.4 21.9 33.4 10.5 38.9 9.8 62.4 13.4 17.4 9.4 21.9 7.1 5.5 66.1 13.1 16.0 19.7 29.5 36.5 50.7 15.8 36.3 9.8 6.3 13.4 32.3 18.7 6.8 6.4 14.0 38.2 21.9 11.8 9.0 6.7 10.9 46.3 11.4 3.7 21.5 28.4 12.6 10.0 13.3 7.9 39.9 23.0 9.4 21.7 14.5 12.6 8.6 4.3 24.6 14.1 13.5 0.0 0.6 0.6 0.7 0.3 1.5 0.1 0.8 0.7 0.2 0.3 0.5 0.6 2.0 0.1 0.6 0.0 0.3 0.8 6.1 14.7 2.8 10.8 2.3 5.3 13.8 4.7 11.2 0.5 10.4 2.4 13.5 6.4 14.8 6.5 7.9 31.2 17.9 14.6 13.1 7.4 21.7 23.2 13.5 7.2 8.3 11.0 0.0 40.3 11.9 81.5 0.0 9.1 26.5 13.8 15.9 9.7 12.5 0.4 14.1 12.5 19.4 12.7 160.0 26.5 27.3 7.5 6.8 1.2 12.9 20.2 14.1 15.0 4.1 5.7 5.1 14.4 9.3 12.7 7.2 8.4 4.3 8.2 12.3 4.0 4.6 28.1 43.1 13.2 4.8 9.6 38.9 1.2 5.9 3.8 6.6 20.8 9.8 3.6 4.4 15.0 25.1 52.9 9.8 4.8 18.3 18.3 SMIM5 C17orf109 ENSG00000204323 "Small integral membrane protein 5" Q71RC9 17 75633434-75641404 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 28.4" "Cell type enhanced" "Detected in many" "Collecting duct cells: 125.0;Distal tubular cells: 92.0;Endometrial ciliated cells: 69.4;Erythroid cells: 142.5;Glandular and luminal cells: 67.6;Urothelial cells: 90.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 56 "plasmacytoid DC: 207.6" "Lineage enriched" "Detected in many" 56 "dendritic cells: 207.6" "Cell line enhanced" "Detected in some" "HEL: 2.3;MCF7: 10.5;OE19: 2.8;SK-BR-3: 4.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA065332, HPA071268" Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 6: Erythroid cells - Oxygen transport" Vesicles "Golgi apparatus" "HPA065332: AB_2685471, HPA071268: AB_2686377" "unprognostic (6.97e-2)" "prognostic favorable (5.52e-4)" "unprognostic (2.13e-2)" "unprognostic (1.24e-1)" "unprognostic (9.31e-2)" "unprognostic (1.05e-4)" "unprognostic (3.29e-2)" "unprognostic (2.16e-2)" "unprognostic (1.82e-1)" "unprognostic (2.66e-2)" "unprognostic (3.52e-3)" "unprognostic (1.10e-1)" "prognostic favorable (1.12e-4)" "unprognostic (2.64e-1)" "unprognostic (4.94e-2)" "unprognostic (8.26e-2)" "unprognostic (2.58e-1)" 1.3 0.6 4.5 1.9 8.5 11.4 1.5 8.5 6.4 8.4 10.7 10.5 9.6 1.2 0.8 27.4 7.4 4.4 12.2 5.0 5.6 28.4 1.4 3.1 1.1 11.2 8.8 2.7 2.5 3.4 2.4 1.9 9.6 4.2 2.6 0.7 7.8 1.9 0.5 14.3 15.2 0.5 7.2 4.8 10.1 2.2 7.8 0.6 15.9 0.3 3.6 6.1 14.6 16.4 1.8 1.2 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 1.1 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 2.3 0.4 0.1 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.1 10.5 0.1 0.0 0.0 2.8 0.1 0.3 0.3 0.0 0.0 2.0 0.8 0.0 0.0 4.5 0.0 0.3 0.6 0.1 0.1 0.2 0.1 0.1 0.1 0.2 0.0 0.1 0.0 0.5 0.5 1.1 0.3 0.6 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 3.7 0.1 0.0 207.6 0.0 13.7 4.5 8.5 8.5 6.4 5.0 5.6 11.2 8.8 9.6 7.2 7.8 16.4 0.7 9.6 7.0 0.7 1.6 1.1 7.3 4.8 0.6 1.5 1.2 0.9 25.1 10.0 13.9 125.0 2.1 3.1 51.9 48.4 92.0 2.9 0.1 69.4 10.1 1.8 14.4 142.5 0.0 0.5 5.8 2.3 26.0 67.6 0.0 0.3 1.8 0.2 0.7 0.0 0.0 16.1 44.7 0.6 0.9 0.3 0.6 17.0 7.2 0.0 1.2 3.3 1.0 0.0 17.9 10.7 54.2 1.5 0.9 7.4 15.5 0.9 48.0 2.1 0.0 1.4 3.1 0.4 0.5 10.0 8.4 32.8 0.8 0.3 2.3 90.6 SMIM6 "C17orf110, ELN" ENSG00000259120 "Small integral membrane protein 6" P0DI80 17 75646243-75647975 "Predicted membrane proteins, Transporters" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "fallopian tube: 24.1;kidney: 22.1;stomach 1: 33.1;testis: 26.1" "Cell type enhanced" "Detected in many" "Early spermatids: 565.7;Endometrial ciliated cells: 233.1;Enteroendocrine cells: 197.1;Late spermatids: 1243.9" "Cancer enhanced" "Detected in many" "endometrial cancer: 12.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 42 "plasmacytoid DC: 34.2" "Lineage enriched" "Detected in single" 42 "dendritic cells: 34.2" "Cell line enhanced" "Detected in some" "A549: 11.7;CACO-2: 3.8;EFO-21: 8.7;HEL: 6.7;Hep G2: 3.6;OE19: 10.5;RPTEC TERT1: 4.2" HPA065721 Uncertain Approved Nucleoplasm Yes NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 21: OE19 - Mitochondria" "Cluster 34: Spermatids - Unknown function" Nucleoplasm "HPA065721: AB_2685546" "unprognostic (4.34e-2)" "unprognostic (3.08e-2)" "unprognostic (7.07e-2)" "prognostic favorable (1.49e-4)" "unprognostic (3.42e-1)" "unprognostic (1.22e-2)" "unprognostic (6.53e-2)" "unprognostic (1.94e-1)" "unprognostic (1.13e-3)" "unprognostic (1.01e-1)" "unprognostic (3.76e-2)" "unprognostic (8.06e-2)" "prognostic favorable (4.09e-4)" "unprognostic (2.77e-1)" "unprognostic (1.38e-1)" "unprognostic (2.58e-2)" "prognostic favorable (1.64e-4)" 0.2 0.1 3.4 0.8 5.8 1.1 0.1 4.9 5.1 2.4 2.5 6.5 9.5 1.1 2.8 0.1 24.1 9.6 0.0 3.6 3.9 22.1 6.6 2.4 0.4 5.4 5.6 0.1 5.6 2.1 0.0 0.3 5.8 0.2 6.6 0.1 0.1 1.4 0.1 0.3 5.9 0.1 4.1 0.2 33.1 26.1 4.7 0.1 0.1 0.0 0.3 1.8 0.1 8.2 0.7 11.7 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 3.8 3.3 0.0 8.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 6.7 0.4 3.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.4 0.0 0.0 0.0 10.5 0.0 0.0 0.0 0.2 4.2 1.9 0.2 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.2 0.2 0.2 0.0 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.8 0.0 34.2 0.0 0.3 3.4 5.8 4.9 5.1 3.6 3.9 5.4 5.6 5.8 4.1 4.7 8.2 0.1 3.2 3.1 0.0 0.9 0.1 3.4 2.3 0.0 0.0 0.2 0.1 0.1 35.8 5.4 35.0 0.0 0.5 9.5 56.2 137.0 35.9 565.7 233.1 2.9 0.8 197.1 0.0 0.0 16.6 3.7 0.3 70.3 22.1 0.0 0.0 0.4 7.0 0.6 0.0 0.0 51.5 8.2 0.0 0.3 1243.9 6.5 1.4 0.0 0.0 1.6 0.0 0.0 0.0 4.5 55.8 129.5 1.9 0.5 2.6 32.7 24.5 38.4 0.0 6.6 0.2 0.4 5.2 2.6 0.0 0.0 4.1 0.9 0.0 4.4 9.6 SPC24 "FLJ90806, SPBC24" ENSG00000161888 "SPC24 component of NDC80 kinetochore complex" Q8NBT2 19 11131520-11155808 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 26.0;lymphoid tissue: 14.7" "Cell type enhanced" "Detected in many" "Erythroid cells: 35.0;Extravillous trophoblasts: 15.5;Hofbauer cells: 14.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA051234 Approved Supported Nucleoplasm,Nucleoli NA Yes "Cluster 40: NK-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Nucleoli "HPA051234: AB_2681397" "unprognostic (1.57e-1)" "prognostic favorable (3.59e-4)" "unprognostic (6.79e-2)" "unprognostic (1.07e-3)" "unprognostic (4.04e-1)" "unprognostic (2.98e-2)" "prognostic unfavorable (1.46e-4)" "unprognostic (1.21e-2)" "unprognostic (1.69e-2)" "unprognostic (1.12e-2)" "prognostic unfavorable (1.22e-4)" "unprognostic (6.12e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.62e-2)" "unprognostic (3.52e-2)" "unprognostic (2.25e-1)" "unprognostic (8.82e-2)" 1.9 1.7 1.3 4.8 1.5 26.0 1.2 3.9 2.1 2.1 1.7 4.7 4.5 2.7 0.8 5.0 1.3 2.3 2.7 1.6 1.5 0.8 1.6 1.6 6.3 1.1 0.8 1.3 1.1 0.4 0.4 3.2 1.3 1.6 4.3 1.2 1.3 2.0 4.0 3.9 4.1 8.1 0.5 3.1 2.9 4.3 1.4 14.7 0.9 1.1 6.5 2.5 2.0 2.4 73.6 26.9 36.9 30.1 5.0 9.7 16.6 42.3 15.7 38.6 43.6 28.4 24.6 58.2 46.0 18.5 22.8 38.8 29.0 30.3 28.7 30.9 24.9 78.5 68.9 43.2 1.1 55.5 33.7 1.9 1.1 27.8 12.8 10.0 34.7 62.3 42.8 118.3 27.6 48.7 76.4 32.9 25.5 19.8 43.9 59.8 56.7 18.6 11.2 23.8 38.4 27.2 37.0 22.4 9.6 17.5 22.0 19.8 33.2 36.8 38.3 49.6 51.2 70.5 39.8 55.6 26.9 53.9 30.5 1.9 0.4 0.4 0.5 0.5 0.4 0.8 0.9 1.5 0.2 0.7 0.9 0.6 2.2 2.0 0.5 0.5 1.7 0.3 1.3 1.5 3.9 2.1 1.6 1.5 1.1 0.8 1.3 0.5 1.4 2.4 0.2 0.0 0.5 0.3 1.5 1.1 1.2 1.3 0.0 0.0 1.0 0.4 9.0 1.5 0.8 5.5 6.2 10.0 0.9 2.8 0.0 0.2 0.3 1.0 2.2 2.2 2.4 35.0 0.3 0.0 15.5 3.5 3.6 1.8 5.7 6.5 4.6 0.7 14.0 0.0 0.3 2.6 0.0 3.0 2.5 3.0 0.6 1.0 0.0 1.0 0.0 2.1 2.1 0.5 0.3 0.3 0.0 0.4 6.3 0.3 0.7 0.6 0.2 0.6 0.0 1.3 2.4 6.9 10.8 2.1 0.3 2.1 2.2 0.5 6.6 1.2 SPI1 "OF, PU.1, SFPI1, SPI-1, SPI-A" ENSG00000066336 "Spi-1 proto-oncogene" P17947 11 47354860-47378547 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, RNA-binding" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "bone marrow: 335.1;lung: 101.0;lymphoid tissue: 172.7" "Group enriched" "Detected in many" 6 "Hofbauer cells: 432.9;Kupffer cells: 411.9;Langerhans cells: 537.6;Macrophages: 453.3;monocytes: 357.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 179.7" "Lineage enriched" "Detected in many" 5 "granulocytes: 179.7" "Cell line enhanced" "Detected in some" "HEL: 90.1;HL-60: 159.7;HMC-1: 282.2;NB-4: 267.8;THP-1: 206.7;U-698: 85.3;U-937: 117.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004079, HPA044653" Enhanced Supported Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm "CAB004079: AB_10692379, HPA044653: AB_2679036" "unprognostic (4.45e-2)" "unprognostic (3.31e-3)" "unprognostic (2.92e-2)" "unprognostic (1.66e-2)" "unprognostic (5.97e-2)" "unprognostic (3.33e-2)" "unprognostic (5.28e-2)" "unprognostic (1.07e-1)" "unprognostic (2.35e-2)" "unprognostic (2.79e-1)" "unprognostic (3.36e-1)" "unprognostic (1.78e-1)" "prognostic unfavorable (2.07e-5)" "unprognostic (1.20e-1)" "unprognostic (4.95e-2)" "unprognostic (2.40e-1)" "unprognostic (4.92e-2)" 36.5 19.7 12.0 107.3 13.1 335.1 17.7 14.3 19.4 7.9 15.8 15.6 21.5 7.3 2.1 9.1 19.1 21.3 13.5 11.7 16.4 10.6 15.6 101.0 65.0 31.2 20.9 5.2 7.8 3.1 7.6 28.0 24.7 10.3 10.2 1.0 14.6 6.1 5.0 13.8 29.3 21.9 19.8 172.7 17.0 3.7 26.2 15.7 8.8 8.3 32.0 29.9 7.6 30.3 0.2 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.0 0.2 0.1 0.0 0.0 72.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 90.1 0.0 0.0 0.0 159.7 282.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 11.7 0.7 0.0 0.0 0.2 267.8 0.2 0.0 0.0 48.7 0.2 47.5 0.0 0.0 0.2 0.3 0.0 0.0 0.6 0.0 0.0 206.7 0.3 0.0 0.5 0.5 0.1 0.1 0.3 85.3 0.3 117.5 0.1 14.1 19.2 179.7 0.0 27.4 0.0 3.9 0.0 0.0 16.4 2.4 0.0 0.0 83.8 0.0 34.7 0.9 0.0 7.3 12.0 13.1 14.3 19.4 11.7 16.4 31.2 20.9 24.7 19.8 26.2 30.3 2.1 3.2 1.1 10.4 72.6 10.5 0.5 0.0 1.2 1.3 2.1 5.0 2.9 4.3 0.6 5.5 0.0 2.3 6.3 0.5 19.6 0.1 7.5 0.1 0.3 5.5 4.2 39.7 3.1 0.4 3.1 2.6 1.1 0.3 33.7 0.2 7.9 3.2 432.9 0.0 3.3 0.3 0.0 411.9 537.6 27.5 1.8 453.3 10.6 36.5 357.5 7.0 8.2 3.5 1.5 0.0 0.1 0.0 21.8 0.4 0.2 2.3 0.7 1.7 13.1 1.5 1.4 5.1 9.3 0.8 9.9 4.2 4.8 1.1 0.4 0.5 ST18 "KIAA0535, NZF-3, NZF3, ZC2H2C3, ZC2HC10, ZNF387" ENSG00000147488 "ST18 C2H2C-type zinc finger transcription factor" O60284 8 52110839-52460959 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "brain: 82.1" "Cell type enriched" "Detected in some" 39 "Oligodendrocytes: 4055.3" "Cancer enhanced" "Detected in single" "pancreatic cancer: 0.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 2.7;SCLC-21H: 9.6;U-87 MG: 1.5" "Region enhanced" "Detected in all" "cerebellum: 40.2" "Low region specificity" "Detected in all" HPA044919 Uncertain NA NA "Cluster 70: Brain - Nervous system development" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA044919: AB_10959756" "unprognostic (3.66e-1)" "unprognostic (4.34e-2)" "unprognostic (7.47e-2)" "unprognostic (2.04e-2)" "unprognostic (2.78e-1)" "unprognostic (2.42e-2)" "unprognostic (1.22e-1)" "unprognostic (7.11e-2)" "unprognostic (2.12e-1)" "unprognostic (1.58e-1)" "unprognostic (1.55e-3)" "unprognostic (2.82e-1)" "unprognostic (2.53e-5)" "unprognostic (3.29e-1)" "unprognostic (1.35e-1)" "unprognostic (9.34e-2)" "unprognostic (9.84e-3)" 0.0 0.9 18.4 0.1 48.6 0.0 0.0 44.1 24.1 0.0 1.7 0.1 0.5 0.0 0.0 0.0 0.0 0.2 0.0 18.0 29.0 0.3 0.1 0.1 0.0 47.8 37.4 0.0 1.9 0.0 4.4 0.1 43.5 0.1 0.3 8.5 0.0 0.0 0.0 0.0 0.5 0.0 22.3 0.0 1.5 0.3 35.7 0.1 0.0 0.0 0.1 0.0 0.0 82.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 2.7 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.4 48.6 44.1 24.1 18.0 29.0 47.8 37.4 43.5 22.3 35.7 82.1 0.0 0.0 0.0 4.9 0.6 0.1 0.1 0.0 0.0 101.5 0.0 0.0 1.1 4.3 0.0 0.0 14.6 0.0 0.0 0.1 0.0 0.0 7.4 0.0 0.0 0.2 49.6 1.3 3.4 0.0 0.4 0.2 5.1 0.0 0.0 0.0 0.0 0.2 1.3 1.7 8.5 0.8 10.2 1.6 11.0 1.7 0.0 3.4 0.0 0.0 0.7 2.4 0.0 13.0 4055.3 0.3 0.0 0.0 0.1 0.3 0.1 0.8 0.0 4.5 0.0 0.0 0.1 0.3 0.3 0.0 0.3 0.1 0.1 0.0 0.3 0.0 STAC3 MGC2793 ENSG00000185482 "SH3 and cysteine rich domain 3" Q96MF2 12 57243453-57251188 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 40 "skeletal muscle: 2315.3;tongue: 1169.0" "Cell type enriched" "Detected in many" 7 "Skeletal myocytes: 287.7" "Cancer enhanced" "Detected in all" "head and neck cancer: 11.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 5.8" "Group enriched" "Detected in many" 6 "dendritic cells: 3.6;monocytes: 5.8" "Cell line enriched" "Detected in many" 23 "RH-30: 2282.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA039285, HPA039527" Enhanced Nucleoplasm,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 37: Myocytes - Muscle contraction" Nucleoplasm Cytosol "HPA039285: AB_2676427, HPA039527: AB_10673424" "unprognostic (6.16e-2)" "prognostic favorable (2.01e-4)" "prognostic unfavorable (7.10e-4)" "unprognostic (1.05e-2)" "unprognostic (1.31e-1)" "unprognostic (5.25e-2)" "unprognostic (1.62e-1)" "unprognostic (1.19e-1)" "unprognostic (2.05e-2)" "unprognostic (1.31e-1)" "unprognostic (9.12e-2)" "unprognostic (1.73e-1)" "prognostic unfavorable (7.11e-6)" "unprognostic (4.58e-2)" "unprognostic (3.36e-1)" "unprognostic (2.09e-1)" "unprognostic (1.14e-3)" 2.7 2.0 2.7 7.3 2.5 17.8 2.1 4.6 5.3 1.4 2.3 2.6 2.0 0.8 2.8 31.2 1.7 2.3 1.5 2.6 2.3 1.8 4.4 6.5 8.9 2.7 2.6 1.0 1.4 2.6 2.1 2.9 2.7 23.0 3.0 3.2 43.9 1.1 2315.3 3.4 2.6 2.5 2.1 9.1 1.7 11.9 2.6 4.1 2.1 1169.0 7.4 2.4 1.3 3.1 0.6 0.8 2.1 4.0 1.3 2.2 0.8 0.5 0.5 0.5 0.7 0.5 1.9 55.0 1.1 1.2 0.0 1.0 0.9 1.1 0.2 1.4 1.0 27.9 0.3 0.6 0.5 17.2 97.1 10.0 1.6 0.4 0.6 1.3 0.9 6.1 2.9 2.2 7.5 5.4 1.6 36.3 0.1 0.8 1.0 13.0 2282.0 2.6 1.3 1.2 1.4 1.1 1.6 1.5 0.3 0.3 0.9 48.4 1.0 0.5 0.4 1.6 0.4 2.2 1.2 9.6 1.1 32.9 0.7 0.0 4.4 0.3 0.0 5.8 0.0 0.7 0.0 0.2 3.6 0.3 0.0 0.1 0.2 0.0 2.9 1.0 0.2 1.4 2.7 2.5 4.6 5.3 2.6 2.3 2.7 2.6 2.7 2.1 2.6 3.1 0.4 0.0 0.6 1.3 1.9 1.5 0.4 1.1 0.6 7.5 1.2 1.4 0.3 1.5 0.4 0.0 2.1 1.0 2.8 0.9 0.0 0.8 13.5 1.1 0.6 0.7 2.4 0.4 3.0 1.0 0.7 0.8 1.1 0.9 5.7 1.5 1.8 1.3 39.9 1.7 2.4 1.2 4.1 37.3 16.3 8.9 1.2 24.1 0.0 0.0 26.3 1.5 0.0 1.5 1.2 0.9 1.0 0.7 0.5 1.0 1.6 0.7 2.3 2.5 0.0 287.7 1.0 3.4 1.4 0.6 0.3 1.4 1.6 0.8 1.2 0.4 SYT13 KIAA1427 ENSG00000019505 "Synaptotagmin 13" Q7L8C5 11 45240302-45286341 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.1;gallbladder: 20.8;pituitary gland: 16.8" "Cell type enriched" "Detected in many" 7 "Enteroendocrine cells: 336.8" "Group enriched" "Detected in many" 5 "breast cancer: 13.5;colorectal cancer: 7.4;pancreatic cancer: 19.9;renal cancer: 16.9;stomach cancer: 11.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 19.1;NTERA-2: 8.8;RPTEC TERT1: 56.8;SCLC-21H: 15.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046224, HPA056602" Uncertain Supported Vesicles NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 17: Intestinal endocrine cells - Hormone signaling" Vesicles "HPA046224: AB_10961288, HPA056602: AB_2683185" "unprognostic (4.96e-2)" "unprognostic (1.06e-2)" "unprognostic (9.92e-2)" "prognostic unfavorable (7.79e-5)" "unprognostic (1.00e-2)" "unprognostic (4.17e-2)" "unprognostic (3.75e-2)" "unprognostic (9.83e-3)" "unprognostic (2.19e-1)" "unprognostic (7.58e-2)" "unprognostic (1.21e-1)" "unprognostic (2.47e-1)" "unprognostic (5.66e-3)" "unprognostic (2.94e-2)" "unprognostic (1.76e-1)" "unprognostic (8.70e-2)" "unprognostic (5.13e-2)" 0.1 4.7 7.0 1.5 12.7 0.0 0.2 1.7 30.1 0.0 0.0 12.2 12.5 0.2 0.0 0.0 0.2 20.8 5.2 18.0 11.5 8.9 0.3 0.5 0.0 5.7 1.2 0.0 7.1 0.4 16.8 0.0 5.4 1.8 12.6 11.3 1.9 0.0 0.1 0.2 12.8 0.8 0.0 0.1 11.0 1.7 9.0 0.3 1.6 0.1 0.0 0.0 0.0 5.2 0.0 19.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.2 0.0 1.1 0.0 0.2 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 8.8 0.0 0.2 0.0 0.0 0.0 56.8 0.0 15.0 0.7 0.0 0.0 0.1 0.7 1.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.2 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 12.7 1.7 30.1 18.0 11.5 5.7 1.2 5.4 0.0 9.0 5.2 0.0 0.0 0.0 4.6 0.1 0.0 0.2 0.0 0.0 3.3 0.1 0.3 15.3 17.2 0.0 3.7 25.0 0.0 0.0 10.2 5.9 1.2 3.1 0.4 0.2 0.1 336.8 0.0 41.6 0.6 0.0 1.7 3.6 2.0 0.0 2.5 0.0 0.0 0.0 1.7 43.8 37.3 4.1 0.0 0.0 9.7 0.3 0.0 0.0 5.6 0.0 0.7 0.0 1.5 3.5 8.2 14.3 0.0 0.0 2.3 13.9 0.5 0.0 2.7 0.0 0.0 0.2 2.0 0.2 0.0 0.0 0.0 0.0 0.0 32.8 0.2 SYTL5 ENSG00000147041 "Synaptotagmin like 5" Q8TDW5 X 38006553-38128819 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 13.6;stomach 1: 12.1" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 37.2;Inhibitory neurons: 92.0;Intestinal goblet cells: 20.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 6.2;MCF7: 5.8;OE19: 8.4;SK-MEL-30: 14.8;SuSa: 19.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA026074 Uncertain Approved Nucleoplasm,Microtubules,Cytosol NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Microtubules, Cytosol" "HPA026074: AB_1857697" "unprognostic (3.60e-2)" "unprognostic (1.71e-1)" "unprognostic (2.35e-1)" "unprognostic (6.68e-2)" "unprognostic (3.09e-3)" "unprognostic (3.22e-2)" "unprognostic (2.01e-2)" "unprognostic (1.94e-1)" "unprognostic (1.72e-1)" "unprognostic (3.35e-1)" "unprognostic (1.10e-1)" "unprognostic (6.72e-2)" "unprognostic (1.30e-2)" "unprognostic (5.21e-2)" "unprognostic (1.51e-1)" "unprognostic (1.47e-2)" "unprognostic (2.96e-2)" 0.0 8.2 6.5 0.3 7.2 0.0 2.5 0.0 5.6 5.6 0.1 2.8 2.2 2.2 0.8 3.1 0.4 0.5 1.1 6.7 10.7 1.2 4.4 0.6 0.0 3.4 13.6 0.1 5.8 0.0 0.6 7.4 6.3 0.9 3.2 0.5 2.2 0.4 0.0 0.1 2.4 3.3 2.5 0.0 12.1 0.6 8.6 0.0 0.1 0.0 0.0 0.9 0.8 0.9 0.0 1.2 0.2 0.0 0.1 0.0 1.3 0.0 0.0 0.0 0.0 6.2 1.4 0.0 0.0 0.5 2.2 0.7 0.0 0.0 0.0 0.0 0.6 0.0 3.0 0.0 0.0 0.0 0.0 0.1 0.4 0.6 0.0 0.7 0.1 0.0 0.1 0.2 0.2 5.8 0.0 0.0 2.5 8.4 0.0 0.0 2.0 0.0 0.0 0.4 3.2 0.0 0.3 1.2 14.8 19.5 0.0 0.0 0.0 0.1 4.7 0.0 3.3 0.1 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 6.5 7.2 0.0 5.6 6.7 10.7 3.4 13.6 6.3 2.5 8.6 0.9 0.0 0.0 2.0 1.6 0.0 0.0 0.2 0.8 0.0 0.0 4.0 1.5 0.3 0.0 8.7 0.0 0.0 3.3 0.0 4.6 0.0 0.0 0.0 0.7 3.6 0.1 3.0 0.0 1.4 0.9 3.6 0.6 37.2 4.0 0.0 1.0 0.4 1.3 0.3 0.0 92.0 20.8 6.1 0.0 0.0 0.0 0.6 0.2 0.0 1.0 0.2 0.0 0.0 0.0 1.1 4.9 3.0 2.6 0.3 0.6 0.6 0.1 3.3 0.0 0.0 0.0 0.7 0.0 0.0 1.0 0.0 8.9 0.1 0.0 0.7 1.0 TACC3 "ERIC-1, ERIC1, maskin, Tacc4" ENSG00000013810 "Transforming acidic coiled-coil containing protein 3" Q9Y6A5 4 1712891-1745171 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 58.9;lymphoid tissue: 52.4;testis: 50.6" "Cell type enhanced" "Detected in many" "Early spermatids: 70.4;Hofbauer cells: 43.9;Late spermatids: 69.9;Spermatocytes: 94.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005781, HPA006050, CAB010111, HPA022039" Enhanced Enhanced "Vesicles,Mitotic spindle,Centriolar satellite,Cytosol" Yes Yes 11000 "Cluster 5: Granulocytes - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Mitotic spindle, Centriolar satellite, Cytosol" Vesicles "CAB010111: AB_628323, HPA005781: AB_1857724, HPA006050: AB_2667505, HPA022039: AB_1857725" "unprognostic (2.95e-1)" "unprognostic (1.18e-1)" "unprognostic (7.71e-2)" "unprognostic (4.35e-2)" "unprognostic (6.58e-2)" "unprognostic (1.84e-2)" "prognostic unfavorable (3.30e-4)" "unprognostic (1.10e-3)" "unprognostic (4.61e-2)" "unprognostic (9.12e-2)" "unprognostic (2.91e-2)" "unprognostic (2.26e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (4.66e-2)" "unprognostic (2.09e-1)" "unprognostic (4.44e-3)" "unprognostic (9.75e-2)" 5.3 3.9 4.2 24.9 4.3 58.9 3.5 5.2 5.3 3.6 5.2 10.3 6.6 3.3 4.8 14.9 2.8 4.2 3.3 4.5 4.4 2.7 3.5 6.5 43.2 4.8 5.3 2.2 1.4 2.3 2.6 8.7 4.8 2.4 10.6 1.9 3.9 2.5 2.0 6.4 12.9 6.4 4.2 22.1 6.4 50.6 5.1 52.4 2.8 3.4 39.3 5.0 5.4 4.7 106.7 88.7 129.5 72.2 6.7 15.2 72.9 114.6 62.1 135.4 87.6 93.5 122.8 133.8 48.0 65.4 149.9 71.4 142.5 86.8 131.1 59.8 77.0 113.8 67.2 85.8 5.9 146.6 85.5 5.2 5.7 85.6 46.0 26.0 102.2 110.3 106.3 90.8 123.8 87.1 207.5 204.0 139.3 89.2 111.6 139.1 90.5 55.0 73.8 125.5 99.8 62.8 70.1 42.3 33.1 95.2 83.3 90.5 56.4 75.4 90.0 65.4 176.7 69.5 102.5 207.1 43.2 141.1 109.1 45.5 30.0 37.9 8.5 12.5 11.1 7.8 16.5 11.5 15.3 10.8 28.3 13.1 91.8 12.2 9.6 8.3 42.5 32.5 4.2 4.3 5.2 5.3 4.5 4.4 4.8 5.3 4.8 4.2 5.1 4.7 6.0 0.0 6.7 2.0 16.5 2.2 1.2 3.2 1.2 1.7 2.4 3.0 2.6 2.8 3.4 9.2 8.4 19.5 6.4 11.2 0.0 2.2 70.4 4.2 2.8 5.2 1.2 37.2 2.3 0.7 20.4 6.0 12.8 4.3 5.1 24.5 8.9 5.1 43.9 5.0 3.2 9.5 4.1 23.2 10.8 69.9 2.8 34.1 0.0 4.7 24.4 1.4 6.2 0.5 0.8 2.9 4.2 2.6 18.0 1.3 2.6 2.8 0.9 2.7 6.6 2.0 4.8 94.3 37.7 12.8 1.4 4.0 23.2 2.2 16.1 2.7 TCF19 SC1 ENSG00000137310 "Transcription factor 19" Q9Y242 6 31158547-31167159 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Erythroid cells: 37.0;Glandular and luminal cells: 17.6;Plasma cells: 21.1" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "A-431: 82.8;GAMG: 47.0;HEK 293: 43.3;JURKAT: 40.9;Karpas-707: 39.2;SCLC-21H: 48.5;U-138 MG: 49.0" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA065994 Approved Nucleoplasm,Nucleoli NA Yes "Cluster 35: T-regs - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Nucleoli "HPA065994: " "unprognostic (1.41e-2)" "unprognostic (4.92e-2)" "unprognostic (4.00e-2)" "unprognostic (5.16e-3)" "unprognostic (1.99e-2)" "unprognostic (6.04e-2)" "prognostic unfavorable (5.66e-4)" "unprognostic (7.04e-2)" "unprognostic (1.35e-2)" "unprognostic (5.92e-2)" "unprognostic (1.74e-3)" "unprognostic (1.56e-2)" "prognostic unfavorable (3.54e-10)" "unprognostic (3.11e-2)" "unprognostic (1.05e-1)" "unprognostic (1.36e-2)" "unprognostic (1.21e-1)" 4.6 1.7 0.3 2.6 0.4 1.0 4.3 0.7 0.4 6.9 0.2 5.8 4.4 4.2 2.1 12.5 3.8 0.4 3.7 0.3 0.3 4.1 2.0 4.4 10.0 0.5 0.4 4.8 3.2 0.0 1.3 0.3 0.5 5.1 1.7 0.6 4.7 0.8 2.7 8.9 7.2 1.1 0.3 9.5 5.5 1.9 0.7 0.0 2.4 0.1 1.7 5.2 8.1 0.3 82.8 0.7 0.7 0.1 5.4 7.0 0.7 0.5 0.0 0.1 0.1 5.3 0.1 0.1 17.7 20.1 47.0 0.1 0.0 30.3 0.0 0.5 43.3 7.3 5.1 2.0 0.0 0.2 21.1 2.9 0.0 2.3 0.0 4.4 17.9 40.9 0.1 39.2 8.1 0.3 1.2 13.2 0.1 0.0 0.0 1.1 4.8 0.7 7.1 0.3 48.5 0.5 0.4 0.1 0.5 6.5 0.1 6.0 0.0 49.0 0.2 0.4 0.4 12.5 15.0 24.8 0.1 0.3 0.3 0.0 0.1 0.0 0.2 0.0 1.3 0.5 0.6 1.1 0.3 0.5 0.8 0.2 0.1 0.4 0.0 0.0 1.0 0.5 0.3 0.4 0.7 0.4 0.3 0.3 0.5 0.4 0.5 0.3 0.7 0.3 2.8 3.2 0.6 0.7 6.7 5.1 3.1 2.5 8.6 3.0 2.8 2.9 1.2 0.0 2.5 3.7 0.0 2.9 3.9 1.8 7.9 1.3 0.3 4.7 2.0 4.7 1.2 37.0 0.1 1.8 9.6 5.6 5.6 17.6 1.3 7.0 1.8 0.6 8.9 1.7 0.2 3.9 2.0 2.9 5.4 0.7 5.0 4.8 12.4 0.0 6.0 4.2 8.2 0.0 0.2 1.1 0.9 6.4 21.1 1.3 1.6 0.4 0.2 0.5 0.0 3.5 5.3 0.7 11.1 9.6 3.8 0.4 7.6 2.0 8.8 2.9 TFF1 "BCEI, D21S21, HP1.A, HPS2, pNR-2, pS2" ENSG00000160182 "Trefoil factor 1" P04155 21 42362282-42366535 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 48 "stomach 1: 7973.0" "Group enriched" "Detected in many" 9 "Gastric mucus-secreting cells: 12908.9;Pancreatic endocrine cells: 14603.3" "Group enriched" "Detected in many" 10 "breast cancer: 402.1;colorectal cancer: 268.3;pancreatic cancer: 805.7;stomach cancer: 744.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 42 "MCF7: 13512.4;OE19: 5337.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB002170, HPA003425" Enhanced "Secreted to digestive system" NA NA 950000 "Cluster 4: Stomach - Digestion" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" "CAB002170: AB_563985, HPA003425: AB_1848260" "prognostic favorable (5.00e-4)" "unprognostic (8.81e-3)" "unprognostic (9.82e-2)" "prognostic favorable (5.67e-4)" "unprognostic (2.42e-1)" "unprognostic (1.72e-3)" "unprognostic (8.14e-2)" "unprognostic (2.45e-1)" "unprognostic (1.52e-1)" "unprognostic (6.62e-2)" "unprognostic (1.01e-1)" "unprognostic (1.19e-1)" "unprognostic (7.72e-3)" "unprognostic (1.07e-1)" 2.3 0.3 0.0 20.3 0.0 0.0 26.7 0.0 0.0 9.7 0.0 114.7 34.8 0.2 0.0 18.3 0.9 167.2 0.6 0.0 0.0 0.9 0.8 1.3 0.2 0.0 0.0 0.2 10.7 0.0 0.2 1.1 0.0 25.0 108.4 0.0 32.4 0.7 0.2 0.1 68.4 4.8 0.0 3.1 7973.0 0.1 0.0 0.2 5.3 0.0 0.2 30.6 2.2 0.0 0.0 42.7 0.0 0.2 0.0 0.0 3.4 0.0 0.0 0.0 0.0 16.2 5.7 0.0 1.1 0.0 1.7 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.1 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 13512.4 4.6 0.5 5.5 5337.9 223.4 1.7 0.0 0.2 0.0 1.4 0.3 0.2 0.0 5.0 0.0 1.3 5.0 0.1 0.0 0.0 3.5 0.1 0.0 3.6 0.6 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 18.7 0.0 6.1 5.9 0.0 0.0 432.7 197.2 0.0 564.7 12.1 35.0 0.0 0.1 3.1 601.9 0.0 245.7 0.0 1.8 0.2 3.5 430.2 0.0 0.0 821.8 3.1 5.1 12908.9 2.9 13.4 0.0 0.0 1.6 0.2 0.0 0.0 1395.6 111.9 0.0 0.0 0.0 0.0 9.2 0.0 0.0 10.3 0.0 0.0 0.0 0.0 14603.3 500.9 0.0 40.6 432.4 78.0 0.0 2.8 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.3 8.9 0.0 80.0 232.6 TFF2 SML1 ENSG00000160181 "Trefoil factor 2" Q03403 21 42346357-42350997 "Cancer-related genes, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "stomach 1: 6852.1" "Group enriched" "Detected in some" 5 "Cholangiocytes: 2057.4;Gastric mucus-secreting cells: 7217.7" "Group enriched" "Detected in many" 11 "pancreatic cancer: 320.9;stomach cancer: 244.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 35.4;Karpas-707: 20.0;OE19: 55.4;PC-3: 145.2" "Not detected" "Not detected" "Not detected" "Not detected" "CAB025834, HPA036705" Enhanced "Secreted to digestive system" NA NA 890000 "Cluster 4: Stomach - Digestion" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 16: Pancreatic endocrine cells - Mixed function" "CAB025834: , HPA036705: AB_2675263" "unprognostic (3.95e-2)" "unprognostic (9.87e-2)" "unprognostic (1.82e-1)" "unprognostic (1.30e-1)" "prognostic unfavorable (1.99e-4)" "unprognostic (1.68e-1)" "unprognostic (1.33e-1)" "unprognostic (4.89e-2)" "unprognostic (5.55e-2)" "unprognostic (1.27e-9)" "unprognostic (1.99e-1)" "unprognostic (2.07e-1)" "unprognostic (1.28e-1)" "unprognostic (5.26e-3)" 1.4 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1.8 0.0 6.5 1424.4 0.1 0.0 3.4 1.2 105.4 0.2 0.0 0.0 0.3 4.0 1.0 0.0 0.0 0.0 0.0 17.2 0.0 0.2 1.0 0.0 0.1 4.2 0.0 2.9 0.0 0.1 0.1 0.5 0.2 0.0 2.7 6852.1 0.0 0.0 0.0 2.2 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 35.4 0.0 0.2 0.0 1.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.0 0.0 0.0 2.9 0.0 2.6 55.4 145.2 1.1 0.0 8.0 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 2.1 0.0 0.0 2.7 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.3 0.0 0.0 0.0 0.0 3.6 0.5 0.2 2057.4 0.0 0.0 0.0 0.0 0.0 3.4 0.0 104.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 93.8 0.2 1.3 7217.7 0.0 0.0 0.5 0.0 6.1 0.0 0.0 0.0 19.7 0.0 0.0 0.0 0.0 0.0 2.9 5.4 0.0 0.6 0.0 0.0 0.0 0.0 833.8 5.5 0.0 11.7 0.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 2.0 0.0 0.1 11.8 TMEM150B "DRAM3, TMEM224, TTN2" ENSG00000180061 "Transmembrane protein 150B" A6NC51 19 55312801-55334048 "Predicted membrane proteins, Transporters" Autophagy "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 5 "intestine: 64.1" "Cell type enhanced" "Detected in some" "Distal enterocytes: 18.1;Kupffer cells: 11.8;monocytes: 8.0;Proximal enterocytes: 68.9" "Cancer enhanced" "Detected in many" "colorectal cancer: 11.6" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "classical monocyte: 5.7" "Group enriched" "Detected in many" 7 "granulocytes: 1.9;monocytes: 5.7" "Cell line enhanced" "Detected in some" "CACO-2: 8.3;HMC-1: 3.8;THP-1: 2.9;U-937: 18.1" "Not detected" "Not detected" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 56: Intestine - Transmembrane transport" "Cluster 32: U-937 - Innate immune response" "Cluster 45: Enterocytes - Digestion" "unprognostic (3.19e-2)" "unprognostic (1.00e-1)" "unprognostic (5.76e-2)" "unprognostic (4.94e-2)" "unprognostic (5.33e-2)" "unprognostic (6.70e-2)" "unprognostic (5.51e-2)" "unprognostic (1.35e-1)" "unprognostic (5.35e-2)" "unprognostic (4.00e-2)" "unprognostic (4.74e-2)" "unprognostic (3.06e-1)" "prognostic unfavorable (6.14e-6)" "unprognostic (1.48e-1)" "unprognostic (1.63e-3)" "unprognostic (2.45e-1)" "unprognostic (1.18e-2)" 3.7 1.8 0.5 5.8 0.8 0.7 1.1 0.4 1.0 0.3 1.2 10.2 64.1 0.4 0.1 0.6 0.8 2.9 0.8 0.4 0.7 3.2 2.2 11.9 3.5 1.3 0.7 0.3 0.9 0.1 0.2 5.6 1.6 0.3 7.3 0.0 0.6 0.4 0.2 0.2 57.0 4.1 0.5 5.7 1.4 0.5 3.4 0.7 0.3 0.2 1.6 2.0 0.3 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 8.3 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 1.6 0.0 1.1 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 1.9 0.0 0.0 0.1 0.1 0.1 1.8 0.0 0.2 0.0 2.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 2.9 0.1 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 18.1 0.1 1.9 5.7 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.8 0.5 0.8 0.4 1.0 0.4 0.7 1.3 0.7 1.6 0.5 3.4 1.3 0.0 0.0 0.0 0.0 0.6 0.1 1.3 0.0 0.0 0.0 0.1 0.0 0.5 1.5 0.0 1.8 0.0 0.0 0.0 18.1 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.4 0.8 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.1 6.7 0.0 0.7 3.5 0.0 11.8 1.3 0.0 0.0 3.2 0.0 0.0 8.0 0.0 0.0 0.0 0.9 0.3 1.4 0.0 0.9 0.6 68.9 0.6 0.0 0.0 0.0 0.2 0.2 0.1 0.1 0.0 0.0 0.0 0.2 0.0 3.7 0.3 TPCN2 TPC2 ENSG00000162341 "Two pore segment channel 2" Q8NHX9 11 69048932-69136316 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 30.5;Melanocytes: 35.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA016561, HPA027080" Supported Approved Nucleoli NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 20: HeLa - Mitochondria" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoli "HPA016561: AB_1858207, HPA027080: AB_10600917" "unprognostic (1.29e-1)" "unprognostic (1.53e-2)" "unprognostic (1.39e-1)" "unprognostic (2.95e-1)" "unprognostic (1.63e-1)" "prognostic unfavorable (2.96e-4)" "unprognostic (7.60e-2)" "unprognostic (7.04e-2)" "unprognostic (3.59e-1)" "prognostic unfavorable (1.49e-4)" "unprognostic (4.15e-2)" "unprognostic (1.89e-2)" "unprognostic (6.87e-2)" "unprognostic (2.22e-1)" "unprognostic (2.24e-3)" "unprognostic (5.01e-2)" "unprognostic (4.88e-2)" 5.8 3.8 2.2 4.8 2.9 4.4 5.2 4.8 3.1 8.9 0.2 11.7 7.6 8.9 3.2 4.6 8.5 3.8 3.9 2.2 1.3 7.5 11.1 4.5 5.8 0.7 0.2 5.8 3.6 2.7 4.2 3.0 0.8 7.2 3.9 4.4 4.1 5.7 4.2 10.0 7.2 4.8 0.1 6.3 4.7 3.2 1.5 3.0 4.3 1.4 4.2 6.3 5.9 3.2 4.6 8.8 3.5 4.9 2.7 3.0 10.5 3.6 3.9 4.7 2.4 8.5 12.4 3.5 5.0 6.9 3.2 9.6 3.2 5.8 2.0 2.7 3.3 7.7 13.7 1.9 3.2 6.5 8.5 4.0 3.2 2.2 2.8 2.4 4.9 8.4 4.7 16.7 2.7 6.9 4.4 9.4 2.4 11.5 3.1 4.6 3.3 6.8 5.1 8.0 2.8 3.6 5.9 11.4 17.0 4.3 7.0 9.1 5.2 3.5 4.5 6.4 4.0 6.8 2.9 4.0 7.7 5.5 8.3 2.9 10.2 2.6 0.9 9.9 0.8 2.4 1.8 2.1 7.7 1.8 1.8 1.9 7.0 6.2 11.7 3.1 2.7 4.4 2.2 2.9 4.8 3.1 2.2 1.3 0.7 0.2 0.8 0.1 1.5 3.2 4.5 9.6 1.5 10.1 6.7 4.0 2.7 3.0 2.2 1.8 2.8 2.5 3.1 5.7 2.3 12.9 2.1 2.6 6.1 4.4 17.6 7.2 17.7 2.1 5.6 4.2 0.0 8.2 30.5 8.6 4.8 4.0 8.6 3.4 2.5 7.3 5.3 18.4 11.9 0.0 22.4 2.6 2.0 12.6 5.5 2.7 6.2 10.2 35.6 4.7 7.7 2.5 3.1 26.2 4.5 4.8 2.6 6.8 8.3 1.5 8.8 9.1 0.8 4.9 6.6 5.1 5.7 2.2 4.4 1.9 3.4 1.9 3.6 3.2 3.6 2.1 TPH1 "TPH, TPRH" ENSG00000129167 "Tryptophan hydroxylase 1" P17752 11 18017564-18042426 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Serotonin biosynthesis" "Monooxygenase, Oxidoreductase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.0;intestine: 19.3;stomach 1: 15.0" "Cell type enriched" "Detected in many" 30 "Enteroendocrine cells: 1466.7" "Cancer enhanced" "Detected in some" "endometrial cancer: 2.4" "Group enriched" "Detected in some" 5 "hypothalamus: 3.4;midbrain: 9.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HL-60: 1.5" "Low region specificity" "Detected in some" "CAB010767, HPA022483" Uncertain Uncertain Cytosol NA NA "Cluster 9: Intestine - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 17: Intestinal endocrine cells - Hormone signaling" Cytosol "CAB010767: AB_261587, HPA022483: AB_1858378" "unprognostic (2.14e-4)" "unprognostic (9.97e-2)" "unprognostic (6.92e-2)" "unprognostic (6.78e-2)" "unprognostic (1.55e-1)" "unprognostic (6.26e-5)" "unprognostic (1.73e-1)" "unprognostic (5.33e-2)" "unprognostic (1.60e-1)" "unprognostic (2.12e-2)" "unprognostic (1.19e-4)" "unprognostic (6.72e-2)" "unprognostic (5.40e-8)" "unprognostic (3.76e-2)" "unprognostic (7.42e-2)" "unprognostic (3.10e-1)" "unprognostic (2.46e-5)" 0.6 0.1 0.2 1.2 0.3 1.1 1.3 0.3 0.3 0.6 4.7 9.0 10.2 0.9 0.9 0.2 0.9 0.1 0.3 0.4 3.4 0.5 0.2 0.8 0.5 0.2 9.0 0.7 0.5 0.1 3.0 0.2 1.1 1.4 19.3 1.8 0.5 0.1 0.4 1.4 11.2 0.2 0.2 0.7 15.0 0.9 0.4 0.3 0.5 0.1 0.7 0.4 0.4 0.3 0.1 0.0 0.5 0.4 0.0 0.0 0.2 0.1 0.1 0.0 0.3 0.6 0.0 0.4 0.1 0.0 0.0 0.2 0.1 0.5 0.2 0.4 1.0 0.7 0.3 1.1 0.0 1.5 0.3 0.0 0.6 0.0 0.2 0.1 0.2 0.8 0.3 0.2 0.0 0.1 0.3 0.2 0.1 0.0 0.1 0.5 0.0 0.0 0.0 0.3 0.4 0.3 0.0 0.1 0.2 0.0 0.0 0.9 0.0 0.1 0.4 0.1 0.5 0.0 0.1 0.3 0.0 0.3 0.4 0.3 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.2 0.3 0.3 0.3 0.4 3.4 0.2 9.0 1.1 0.2 0.4 0.3 1.4 0.0 0.0 1.0 1.1 0.4 0.4 0.5 0.0 14.9 1.9 1.0 0.8 0.0 0.1 5.5 2.1 0.2 0.6 1.7 0.0 0.2 0.8 0.1 0.6 0.7 1466.7 0.4 0.5 0.6 0.0 1.2 2.0 0.2 0.0 5.6 0.4 0.2 0.2 1.7 0.4 48.2 0.0 0.3 1.4 0.8 0.9 0.5 0.0 0.0 0.1 1.4 1.0 0.0 0.6 0.4 13.4 1.2 0.3 2.3 1.5 0.3 0.9 5.6 6.6 1.3 1.3 2.8 3.7 0.0 1.4 0.0 1.2 0.0 2.7 0.4 TRIP13 16E1BP ENSG00000071539 "Thyroid hormone receptor interactor 13" Q15645 5 892884-919357 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Meiosis, Oogenesis, Spermatogenesis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 29.9" "Cell type enhanced" "Detected in many" "Early spermatids: 115.4;Late spermatids: 206.9;Respiratory ciliated cells: 79.9;Spermatocytes: 86.4;Spermatogonia: 70.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA005727, HPA053093" Enhanced Approved Nucleoplasm NA NA 78000 "Cluster 40: NK-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "HPA005727: AB_10603220, HPA053093: AB_2682042" "unprognostic (1.65e-2)" "unprognostic (1.65e-1)" "unprognostic (8.59e-2)" "prognostic unfavorable (3.93e-4)" "unprognostic (2.34e-2)" "unprognostic (3.96e-2)" "prognostic unfavorable (1.30e-6)" "unprognostic (4.44e-3)" "unprognostic (1.73e-3)" "prognostic favorable (1.39e-4)" "unprognostic (4.25e-2)" "unprognostic (2.24e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (5.04e-2)" "unprognostic (1.99e-1)" "unprognostic (1.31e-1)" "unprognostic (3.34e-1)" 1.4 0.7 2.0 4.4 2.1 6.0 2.7 0.9 1.8 1.5 1.0 3.8 3.5 1.8 0.6 4.6 6.7 0.7 0.4 1.6 1.5 1.1 0.8 1.3 7.1 1.3 2.0 2.0 1.3 0.2 1.6 3.3 1.4 0.8 5.7 0.5 1.0 0.4 0.6 2.3 3.6 3.5 1.1 1.9 1.7 29.9 1.9 9.3 0.5 0.3 8.4 1.9 1.7 1.2 67.5 73.9 46.6 69.6 4.3 10.1 51.8 68.6 33.1 103.4 96.7 72.2 43.4 59.1 48.7 39.5 90.1 48.7 100.3 47.6 129.1 91.0 83.7 40.6 136.4 52.3 1.1 67.3 23.9 4.7 3.6 87.0 37.3 10.7 51.5 45.9 61.7 50.2 71.7 45.7 67.6 60.6 53.0 37.7 69.4 38.8 87.3 113.0 29.3 34.2 47.9 49.0 103.1 38.2 20.8 40.2 71.3 32.0 26.4 55.6 70.4 46.5 79.0 31.9 68.9 64.6 34.2 79.3 63.1 0.0 0.0 0.0 0.4 0.0 0.2 1.1 0.6 0.7 0.1 1.2 0.2 0.1 0.0 1.6 0.1 1.0 2.1 0.4 2.0 2.1 0.9 1.8 1.6 1.5 1.3 2.0 1.4 1.1 1.9 1.2 0.7 0.0 1.1 0.3 4.3 3.4 3.5 7.3 4.0 0.9 2.2 1.8 0.3 0.0 5.0 0.0 0.0 8.6 0.7 2.2 0.0 3.0 115.4 29.3 2.1 2.5 4.2 14.3 1.3 2.0 25.2 3.4 1.5 3.8 5.7 9.8 2.2 0.4 7.3 3.3 0.5 3.0 4.1 1.3 4.2 206.9 2.1 1.7 0.0 0.0 1.1 0.7 0.0 0.0 0.4 2.2 1.8 2.2 18.1 2.8 0.5 1.2 79.9 0.9 6.6 2.5 5.2 86.4 70.1 7.6 1.4 3.4 3.2 2.7 5.1 3.3 TROAP TASTIN ENSG00000135451 "Trophinin associated protein" Q12815 12 49323236-49331731 "Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 51.0;lymphoid tissue: 36.7;testis: 29.1" "Cell type enhanced" "Detected in many" "Early spermatids: 71.5;Erythroid cells: 75.6;Late spermatids: 70.2;Spermatocytes: 29.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 8.6" "Lineage enriched" "Detected in many" 4 "T-cells: 8.6" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA044102 Uncertain NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 21: OE19 - Mitochondria" "Cluster 12: Non-specific - Cell cycle regulation" "HPA044102: AB_10963691" "unprognostic (1.47e-1)" "unprognostic (2.76e-2)" "unprognostic (1.09e-1)" "unprognostic (3.92e-3)" "unprognostic (1.97e-1)" "unprognostic (4.29e-2)" "prognostic unfavorable (1.39e-5)" "unprognostic (3.43e-3)" "unprognostic (2.88e-2)" "unprognostic (2.65e-3)" "unprognostic (1.08e-3)" "unprognostic (3.51e-2)" "unprognostic (0.00e+0)" "unprognostic (1.80e-1)" "unprognostic (1.54e-1)" "unprognostic (1.92e-1)" "unprognostic (5.17e-2)" 1.3 1.5 0.2 7.3 0.3 51.0 1.4 0.2 0.7 2.8 0.2 6.7 9.0 1.2 0.5 13.5 0.7 0.8 0.8 0.2 0.2 0.9 1.6 2.4 11.2 0.4 0.2 0.8 0.8 0.7 0.4 5.1 0.3 0.9 9.2 0.6 2.5 0.4 0.3 7.7 7.6 2.8 0.1 7.0 5.4 29.1 0.5 36.7 0.8 0.3 14.5 1.9 5.3 0.3 95.9 73.9 92.4 69.7 2.8 6.2 71.2 45.4 43.4 129.5 73.1 163.7 73.5 64.6 21.9 33.7 70.7 74.6 70.4 44.0 75.7 51.9 101.8 90.9 120.4 53.7 1.9 66.5 93.8 1.5 6.0 86.9 59.8 21.1 75.1 68.0 57.2 108.9 52.7 123.0 122.9 101.8 43.4 269.3 110.2 62.5 78.6 83.9 31.7 35.0 59.9 41.0 56.0 107.4 32.7 53.6 88.2 50.1 25.0 33.5 91.2 69.4 124.8 58.3 68.8 83.0 32.3 73.8 38.4 0.2 0.0 0.1 0.1 0.0 0.2 1.4 2.1 2.3 0.3 1.4 0.1 0.5 0.0 2.0 0.1 0.0 8.6 0.5 0.2 0.3 0.2 0.7 0.2 0.2 0.4 0.2 0.3 0.1 0.5 0.3 0.1 0.0 0.0 0.0 4.6 3.8 1.5 2.8 1.2 0.6 2.1 2.8 0.5 0.0 1.8 0.0 0.0 14.1 1.0 3.7 0.0 0.7 71.5 1.9 1.3 1.9 1.2 75.6 0.0 0.7 23.6 3.3 10.2 2.7 0.0 16.0 5.7 1.1 15.7 0.0 0.0 7.9 10.2 6.7 3.7 70.2 1.8 4.0 1.8 0.0 0.9 0.0 6.2 0.0 0.0 0.8 1.8 0.4 17.0 1.1 0.7 0.1 0.2 0.4 0.0 0.7 3.5 29.1 9.3 15.6 2.0 4.0 2.5 0.9 12.7 3.6 UBE2C UBCH10 ENSG00000175063 "Ubiquitin conjugating enzyme E2 C" O00762 20 45812576-45816957 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 78.5;lymphoid tissue: 113.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 129.6;Erythroid cells: 182.1;Extravillous trophoblasts: 449.1;Granulosa cells: 119.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "T-reg: 8.2" "Group enriched" "Detected in many" 5 "granulocytes: 2.1;NK-cells: 2.1;T-cells: 8.2" "Low cell line specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basal ganglia: 4.3;white matter: 11.4" "Low region specificity" "Detected in some" "CAB011464, HPA034569, CAB035990, HPA054975" Approved Approved "Plasma membrane,Cytosol" Yes Yes "Cluster 35: T-regs - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Cytosol" "CAB011464: AB_442965, CAB035990: , HPA034569: AB_2674226, HPA054975: AB_2682658" "unprognostic (1.45e-2)" "unprognostic (2.19e-1)" "unprognostic (1.06e-1)" "unprognostic (2.11e-3)" "unprognostic (2.54e-1)" "unprognostic (1.35e-1)" "prognostic unfavorable (6.24e-6)" "unprognostic (2.27e-3)" "unprognostic (2.59e-2)" "unprognostic (1.04e-1)" "prognostic unfavorable (6.91e-4)" "unprognostic (3.76e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.09e-1)" "unprognostic (3.61e-1)" "unprognostic (4.65e-2)" "unprognostic (2.68e-1)" 2.6 2.9 0.3 21.5 0.3 78.5 4.3 0.9 0.6 6.1 0.7 26.7 21.4 5.7 0.6 37.2 1.9 2.7 1.4 0.2 0.3 1.9 2.9 5.4 45.3 0.3 0.7 1.3 1.0 0.4 0.4 20.4 0.7 1.5 30.9 0.2 5.0 0.9 0.9 18.5 20.6 10.5 0.2 15.8 13.0 16.4 1.6 113.5 1.1 0.2 69.5 6.9 12.3 0.4 312.8 223.9 390.9 188.3 10.4 24.0 225.2 238.5 121.6 390.7 278.4 743.8 345.4 327.6 233.2 115.5 475.6 294.9 2.2 260.5 395.8 141.7 213.7 101.5 168.5 196.0 3.0 145.4 241.6 7.6 27.8 265.7 257.3 57.4 193.4 206.4 1.8 261.6 325.4 516.2 243.5 41.1 237.1 350.8 529.4 256.0 354.8 1.4 134.9 105.9 226.1 188.7 378.3 271.7 154.4 196.2 276.6 209.4 70.1 341.2 298.4 236.2 473.4 84.3 2.9 369.4 208.0 103.4 328.6 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.8 1.7 0.6 0.1 0.1 0.1 2.1 2.1 0.5 0.3 8.2 3.2 0.3 0.3 0.9 0.6 0.2 0.3 0.3 0.7 0.7 0.2 1.6 0.4 0.9 0.0 3.7 0.0 17.9 17.3 7.8 39.0 5.7 0.0 8.6 14.6 0.0 1.5 9.3 0.0 0.0 129.6 3.6 27.4 0.0 1.3 12.0 5.8 5.9 9.5 1.2 182.1 0.0 0.5 449.1 28.5 25.5 9.6 5.7 119.0 18.2 3.6 92.6 0.0 0.1 41.1 50.8 20.8 18.1 6.4 0.9 24.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 1.5 7.2 0.0 37.0 12.6 6.2 0.6 1.8 0.0 0.0 0.5 19.2 52.2 50.7 83.2 11.6 31.2 13.7 2.5 68.4 18.4 UNC13A "KIAA1032, Munc13-1" ENSG00000130477 "Unc-13 homolog A" Q9UPW8 19 17601328-17688365 "Predicted intracellular proteins" "Differentiation, Exocytosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "brain: 24.0;pituitary gland: 32.2;retina: 18.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 43.9;Cone photoreceptor cells: 54.2;Excitatory neurons: 85.3;Horizontal cells: 119.5;Inhibitory neurons: 67.0" "Cancer enhanced" "Detected in some" "glioma: 2.6" "Group enriched" "Detected in many" 15 "amygdala: 8.3;basal ganglia: 15.8;cerebral cortex: 24.0;hippocampal formation: 19.0;white matter: 8.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 16.2;NTERA-2: 23.7;SCLC-21H: 38.9;SH-SY5Y: 9.2" "Low region specificity" "Detected in all" NA NA "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 62: Horizontal cells - Visual perception" "unprognostic (1.50e-1)" "unprognostic (2.61e-1)" "unprognostic (1.02e-1)" "unprognostic (4.96e-3)" "unprognostic (1.69e-1)" "unprognostic (3.98e-3)" "unprognostic (2.13e-3)" "unprognostic (2.40e-1)" "unprognostic (2.32e-1)" "unprognostic (1.89e-1)" "unprognostic (4.33e-3)" "unprognostic (1.40e-2)" "unprognostic (8.19e-3)" "unprognostic (1.94e-1)" "unprognostic (4.83e-2)" "unprognostic (2.14e-2)" "unprognostic (2.00e-1)" 0.1 2.5 8.3 0.4 15.8 0.0 0.0 0.0 24.0 0.3 0.0 0.3 0.2 0.1 0.1 0.0 0.1 0.1 0.0 19.0 1.0 0.3 0.0 0.2 0.3 0.0 0.0 0.2 1.4 0.1 32.2 0.2 0.0 0.1 0.2 18.8 0.0 0.1 0.0 0.0 0.2 0.2 0.0 2.0 0.8 0.7 0.0 0.1 0.2 0.0 0.3 0.1 0.1 8.8 0.0 2.4 2.0 0.4 0.0 0.0 1.0 0.2 0.0 0.0 0.0 0.0 2.4 0.6 3.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 16.2 0.0 0.0 0.0 1.5 0.4 0.0 0.1 2.0 0.1 0.0 0.2 0.0 0.0 23.7 0.2 0.6 0.6 0.0 0.3 0.0 0.0 38.9 9.2 0.0 0.0 0.5 0.2 0.1 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.3 15.8 0.0 24.0 19.0 1.0 0.0 0.0 0.0 0.0 0.0 8.8 0.2 0.0 0.0 6.5 0.0 0.3 0.3 0.1 0.0 43.9 0.1 0.3 2.1 0.0 0.0 0.0 54.2 0.0 0.2 0.3 0.0 1.5 0.0 0.1 0.2 1.0 8.4 0.0 85.3 0.2 0.0 1.5 0.0 0.5 0.0 0.4 0.0 0.0 0.2 119.5 67.0 0.0 2.0 0.0 0.3 0.1 0.0 0.2 0.0 3.7 1.6 3.3 0.0 18.1 2.8 1.1 0.0 1.5 0.0 0.4 0.0 0.1 0.0 22.7 0.0 0.6 0.6 0.2 1.8 0.0 0.0 0.0 0.0 1.8 0.5 0.3 VILL ENSG00000136059 "Villin like" O15195 3 37988059-38007188 "Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "intestine: 61.9;stomach 1: 97.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 221.7;Gastric mucus-secreting cells: 192.7;Paneth cells: 139.0;Proximal enterocytes: 165.6" "Cancer enhanced" "Detected in many" "pancreatic cancer: 22.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 25.0;OE19: 78.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA035675, HPA035676" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cytosol" "Nucleoli fibrillar center" "HPA035675: AB_10671223, HPA035676: " "unprognostic (7.86e-3)" "unprognostic (7.37e-3)" "unprognostic (1.43e-1)" "unprognostic (2.03e-2)" "prognostic unfavorable (1.35e-4)" "prognostic favorable (1.75e-4)" "unprognostic (1.69e-1)" "unprognostic (1.44e-1)" "unprognostic (1.38e-1)" "unprognostic (2.18e-1)" "unprognostic (1.03e-2)" "unprognostic (2.95e-2)" "unprognostic (3.66e-3)" "unprognostic (5.55e-2)" "unprognostic (1.09e-1)" "unprognostic (1.15e-1)" "unprognostic (7.43e-3)" 5.4 3.7 8.7 11.0 9.0 12.6 6.4 6.6 10.6 9.5 6.4 46.8 61.9 5.7 1.5 7.2 6.7 15.7 6.4 8.6 7.8 5.3 1.4 7.7 9.8 8.3 8.4 6.8 3.4 1.2 5.1 4.1 8.0 16.0 26.6 1.2 5.7 4.0 1.2 9.1 61.7 4.1 8.0 11.8 97.5 5.4 8.2 10.2 7.4 1.4 6.3 17.5 7.4 7.2 8.2 0.1 0.2 0.4 2.8 2.2 0.8 2.3 1.9 2.3 2.2 6.1 25.0 3.9 3.5 1.6 0.0 1.9 1.8 0.2 0.5 0.8 0.0 7.3 0.1 0.6 3.4 7.7 9.5 3.3 2.2 2.2 0.0 0.0 4.5 16.1 7.3 2.3 2.6 0.1 12.4 8.7 0.2 78.4 0.0 4.8 0.0 2.0 0.8 9.8 0.1 0.3 0.0 0.5 1.8 0.0 0.7 12.4 2.8 1.0 0.3 3.0 0.0 1.4 3.1 1.2 0.6 10.9 5.0 0.0 3.2 0.0 6.8 2.0 7.4 3.5 4.4 3.9 2.1 4.6 5.6 4.2 0.1 3.4 1.4 3.8 5.8 4.1 8.7 9.0 6.6 10.6 8.6 7.8 8.3 8.4 8.0 8.0 8.2 7.2 4.9 9.6 7.4 10.4 7.2 2.3 5.7 25.5 6.8 0.9 3.3 2.9 1.9 8.6 46.1 0.0 0.0 3.0 13.3 221.7 0.0 3.4 6.2 1.5 2.7 4.5 9.6 6.1 5.5 16.9 3.4 6.7 192.7 1.5 8.2 6.1 5.3 0.3 2.4 1.7 3.0 64.4 14.2 1.9 2.4 19.9 3.7 4.0 1.8 3.7 4.2 28.1 7.2 2.5 1.2 38.7 139.0 2.6 4.4 6.2 165.6 1.6 40.5 0.8 0.0 4.3 7.1 5.4 3.4 3.1 1.4 1.0 8.1 5.6 50.5 33.4 VSIG4 "CRIg, Z39IG" ENSG00000155659 "V-set and immunoglobulin domain containing 4" Q9Y279 X 66021738-66040125 "Plasma proteins, Predicted membrane proteins" "Complement alternate pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 166.0" "Group enriched" "Detected in many" 5 "Hofbauer cells: 989.8;Kupffer cells: 590.9;Macrophages: 328.4" "Cancer enriched" "Detected in all" 5 "glioma: 88.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 27 "classical monocyte: 18.7;intermediate monocyte: 11.1;myeloid DC: 17.8" "Group enriched" "Detected in many" 31 "dendritic cells: 17.8;monocytes: 18.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA003903, CAB026000" Enhanced Uncertain "Nucleoli,Plasma membrane,Cytosol" NA NA 59000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 19: Lung - Lung function" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane, Cytosol" Nucleoli "CAB026000: , HPA003903: AB_1858776" "unprognostic (6.87e-3)" "unprognostic (4.79e-2)" "prognostic unfavorable (1.34e-4)" "unprognostic (3.19e-1)" "unprognostic (1.30e-2)" "unprognostic (1.53e-2)" "unprognostic (9.37e-3)" "unprognostic (1.24e-1)" "unprognostic (3.10e-1)" "unprognostic (1.37e-3)" "unprognostic (1.06e-1)" "unprognostic (2.77e-1)" "prognostic unfavorable (1.95e-6)" "unprognostic (3.70e-2)" "unprognostic (5.45e-2)" "unprognostic (3.37e-2)" "unprognostic (3.47e-2)" 137.1 68.8 17.9 44.2 18.8 7.8 44.2 17.0 36.6 14.1 21.5 40.9 22.5 15.5 5.3 15.4 66.8 39.6 30.0 18.2 18.3 17.9 51.0 166.0 27.8 25.1 23.6 12.9 14.3 6.8 7.0 139.6 25.8 10.6 31.7 2.2 24.5 9.3 8.2 10.8 43.9 108.3 18.9 69.3 22.9 7.3 37.6 5.4 12.3 12.5 1.8 61.5 11.6 26.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 18.7 0.1 0.0 11.1 0.0 0.0 0.0 0.2 17.8 0.1 0.0 0.0 0.5 0.0 0.4 0.1 0.0 5.6 17.9 18.8 17.0 36.6 18.2 18.3 25.1 23.6 25.8 18.9 37.6 26.7 1.3 3.2 16.1 0.0 1.2 2.3 0.3 0.0 0.0 0.0 2.6 0.5 1.8 7.2 3.1 0.0 0.0 5.3 0.3 0.0 0.0 0.1 7.9 0.0 0.0 10.4 0.0 0.0 0.0 0.0 4.9 2.7 0.0 0.0 3.8 0.0 5.0 3.2 989.8 0.0 0.0 0.0 0.0 590.9 111.8 16.6 1.5 328.4 3.6 12.2 1.5 0.5 0.0 0.5 0.0 0.0 0.1 0.4 0.3 0.3 0.0 0.1 4.4 0.0 6.6 0.6 2.0 0.3 0.9 0.5 1.7 12.3 1.5 0.0 0.0 0.2 VSTM2L "C20orf102, dJ1118M15.2" ENSG00000132821 "V-set and transmembrane domain containing 2 like" Q96N03 20 37903111-37945350 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 87.0;heart muscle: 81.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 25.2;Cholangiocytes: 61.5;Club cells: 28.7;Inhibitory neurons: 44.0;Respiratory ciliated cells: 83.0" "Group enriched" "Detected in all" 5 "lung cancer: 23.6;pancreatic cancer: 34.4;prostate cancer: 72.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 67.2;HDLM-2: 98.8;hTCEpi: 23.4;SH-SY5Y: 22.5;SK-BR-3: 81.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043832 Uncertain "Secreted - unknown location" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 44: HDLM-2 - Immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA043832: AB_10968449" "unprognostic (1.43e-1)" "unprognostic (1.38e-1)" "unprognostic (2.33e-2)" "prognostic unfavorable (1.63e-5)" "unprognostic (4.96e-3)" "unprognostic (1.56e-1)" "unprognostic (1.83e-2)" "unprognostic (1.39e-1)" "unprognostic (1.52e-1)" "unprognostic (2.34e-3)" "unprognostic (9.86e-2)" "unprognostic (2.00e-1)" "unprognostic (1.85e-3)" "unprognostic (1.29e-3)" "unprognostic (1.68e-1)" "unprognostic (9.66e-2)" "prognostic unfavorable (8.14e-4)" 0.7 6.1 33.9 0.8 33.8 0.0 0.5 1.3 76.9 12.5 0.0 3.2 1.2 1.7 9.7 1.0 15.5 17.5 81.8 87.0 38.7 1.4 3.0 11.5 0.4 19.1 36.5 0.3 2.6 0.0 17.3 0.8 10.6 9.2 0.4 3.0 7.3 16.2 1.1 1.0 1.2 0.8 41.8 29.6 7.9 4.9 45.9 3.0 1.7 0.0 1.0 0.7 0.6 20.0 0.0 0.8 7.7 0.3 0.3 0.4 0.2 0.9 0.0 0.0 0.0 0.3 67.2 0.0 0.4 0.6 0.3 0.2 0.1 3.2 0.0 98.8 1.9 0.1 0.1 0.0 3.6 0.1 2.5 3.2 23.4 0.1 0.7 2.4 0.0 0.1 0.0 0.0 8.4 0.0 0.1 0.1 0.2 2.3 20.1 0.0 0.0 0.3 0.1 0.0 2.6 22.5 2.7 81.0 0.8 0.0 0.4 0.0 4.6 0.0 0.6 0.2 1.5 0.2 0.1 0.0 0.5 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 33.9 33.8 1.3 76.9 87.0 38.7 19.1 36.5 10.6 41.8 45.9 20.0 0.1 6.4 1.8 2.0 0.1 0.4 1.2 10.7 1.8 8.5 1.0 0.0 25.2 61.5 28.7 0.0 8.4 0.6 1.3 0.2 0.0 3.7 0.4 0.1 0.5 0.3 18.6 0.0 17.8 0.2 0.2 1.8 4.1 0.0 0.0 1.5 2.9 1.3 0.0 13.5 44.0 1.2 10.2 0.8 1.5 0.9 5.3 0.9 0.0 1.9 0.0 0.9 0.0 3.0 3.2 7.9 2.6 16.1 0.1 5.3 0.1 1.0 83.0 4.6 0.0 0.0 2.9 0.2 0.8 0.1 0.6 0.1 1.2 3.5 0.2 0.7 WDFY4 "C10orf64, Em:AC060234.3, FLJ45748, KIAA1607" ENSG00000128815 "WDFY family member 4" Q6ZS81 10 48684876-48982956 "Predicted intracellular proteins, Predicted membrane proteins" Autophagy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 11.7;lymphoid tissue: 28.5" "Cell type enhanced" "Detected in some" "B-cells: 44.7;dendritic cells: 29.9;Early spermatids: 47.2;Langerhans cells: 30.6;Macrophages: 24.6;Microglial cells: 81.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "memory B-cell: 14.3;myeloid DC: 11.3;naive B-cell: 21.2;neutrophil: 10.2;plasmacytoid DC: 32.5" "Group enriched" "Detected in many" 7 "B-cells: 21.2;dendritic cells: 32.5;granulocytes: 10.2" "Cell line enhanced" "Detected in some" "Daudi: 61.0;HDLM-2: 56.3;HL-60: 21.5;THP-1: 18.9;U-698: 25.6;U-937: 25.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA040634 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm Cytosol "HPA040634: AB_10795491" "unprognostic (6.20e-2)" "unprognostic (6.60e-3)" "unprognostic (1.87e-1)" "unprognostic (3.31e-2)" "unprognostic (1.87e-1)" "unprognostic (9.38e-4)" "unprognostic (9.41e-2)" "unprognostic (3.89e-3)" "unprognostic (2.15e-2)" "unprognostic (3.74e-1)" "unprognostic (3.49e-2)" "unprognostic (9.64e-2)" "unprognostic (3.21e-1)" "unprognostic (1.34e-1)" "unprognostic (1.35e-2)" "unprognostic (1.97e-1)" "unprognostic (3.76e-2)" 1.9 0.7 3.2 12.1 3.4 11.7 1.4 4.2 4.8 1.1 3.2 1.9 1.5 0.8 1.9 1.4 0.7 3.2 0.6 3.2 4.2 0.8 1.3 5.2 28.5 6.0 4.9 0.6 1.0 0.4 0.3 1.2 6.2 0.8 1.9 0.1 1.3 0.6 0.7 2.6 7.4 1.7 5.9 17.3 2.3 3.7 6.3 12.3 0.6 0.4 23.9 3.1 0.3 9.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 61.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 56.3 0.0 6.5 0.0 0.0 0.0 21.5 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.1 0.0 0.0 0.0 0.0 11.9 0.0 0.0 0.0 6.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 25.6 0.0 25.0 0.0 0.0 3.0 0.0 0.0 2.8 0.0 14.3 0.0 0.1 11.3 21.2 0.0 0.0 10.2 0.0 1.3 32.5 0.0 1.1 3.2 3.4 4.2 4.8 3.2 4.2 6.0 4.9 6.2 5.9 6.3 9.3 0.2 0.0 1.1 2.0 44.7 0.4 0.1 0.0 0.0 0.0 0.1 0.4 1.3 0.0 0.6 1.8 0.0 0.1 29.9 0.0 1.9 0.0 47.2 0.0 0.1 0.3 0.0 0.4 0.7 0.0 0.2 1.1 0.0 0.0 5.7 0.0 0.0 0.0 13.0 0.0 0.4 0.1 0.0 12.9 30.6 17.7 0.3 24.6 1.8 81.5 16.4 0.0 0.0 1.0 0.5 0.0 0.0 0.4 3.3 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.2 2.9 0.5 0.2 0.3 0.3 1.5 0.0 0.3 0.1 XRCC2 FANCU ENSG00000196584 "X-ray repair cross complementing 2" O43543 7 152644776-152676141 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" DNA-binding "Cancer-related genes, Fanconi anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 5.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 14.1;Extravillous trophoblasts: 21.2;Granulosa cells: 20.2;Spermatocytes: 31.3;Spermatogonia: 19.1;Syncytiotrophoblasts: 12.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065153 Approved Nucleoplasm,Vesicles NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Vesicles" "HPA065153: AB_2685422" "unprognostic (9.31e-3)" "unprognostic (8.25e-2)" "unprognostic (1.62e-1)" "unprognostic (5.53e-3)" "unprognostic (9.10e-2)" "unprognostic (2.52e-2)" "unprognostic (3.36e-5)" "unprognostic (9.98e-3)" "unprognostic (5.82e-3)" "unprognostic (4.04e-3)" "unprognostic (1.06e-3)" "unprognostic (2.43e-2)" "unprognostic (1.55e-15)" "unprognostic (4.52e-3)" "unprognostic (3.01e-1)" "unprognostic (5.14e-1)" "unprognostic (1.73e-2)" 0.2 0.2 0.9 2.3 0.6 5.3 1.5 1.6 2.8 0.3 0.0 1.1 1.7 1.1 0.9 1.0 0.5 0.4 1.0 0.6 1.9 0.4 0.4 0.5 2.9 0.6 0.6 1.0 0.0 0.6 0.0 2.1 1.4 0.7 1.7 1.9 0.2 0.4 0.1 1.9 1.5 0.5 1.1 1.0 1.0 3.0 1.0 3.6 0.6 0.0 2.5 0.5 0.1 1.9 16.5 10.4 18.3 15.8 1.1 1.8 15.0 11.8 3.9 8.2 10.3 14.7 12.8 24.8 9.5 3.5 13.7 13.7 12.8 7.1 19.3 8.9 17.3 16.8 15.5 10.0 0.3 27.3 9.3 0.9 1.1 15.6 3.6 2.0 3.8 15.5 34.2 22.8 8.3 12.6 32.4 21.2 21.6 10.8 12.9 22.8 19.3 15.3 3.1 10.3 16.7 18.1 11.7 7.6 5.0 11.3 5.4 8.3 4.2 17.2 6.9 13.3 23.0 8.8 14.5 19.0 11.0 20.9 20.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.9 0.6 1.6 2.8 0.6 1.9 0.6 0.6 1.4 1.1 1.0 1.9 0.2 0.0 1.1 1.6 1.9 1.3 1.0 1.0 0.0 4.9 0.8 0.4 2.9 0.0 1.4 1.8 0.0 11.2 0.4 0.9 0.0 1.1 11.7 0.9 1.9 1.1 0.0 14.1 2.3 0.2 21.2 2.5 3.1 1.4 0.0 20.2 1.1 0.2 2.4 0.0 2.0 1.7 2.0 0.6 0.8 4.9 0.9 0.8 0.0 0.0 0.6 1.1 3.1 4.5 2.0 0.5 0.1 1.2 6.1 0.6 0.3 0.3 0.1 2.3 0.0 1.9 1.8 31.3 19.1 2.7 1.4 12.6 2.2 1.2 2.3 1.0