Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" ADORA3 AD026 ENSG00000282608 "Adenosine A3 receptor" P0DMS8 1 111499429-111503633 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 21.8" "Cell type enhanced" "Detected in some" "Hofbauer cells: 17.9;Kupffer cells: 79.2;Late spermatids: 18.2;Macrophages: 26.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 40 "eosinophil: 601.6" "Lineage enriched" "Detected in many" 40 "granulocytes: 601.6" "Cell line enriched" "Detected in some" 9 "HMC-1: 108.1" "Low region specificity" "Detected in many" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" 4.5 15.0 8.9 4.3 9.2 0.2 5.5 10.6 14.6 4.4 8.8 6.6 4.5 1.9 0.2 2.5 3.6 5.8 3.4 8.8 12.3 1.6 3.3 3.5 6.4 16.1 11.1 1.8 1.8 3.1 2.6 2.8 14.9 2.4 5.1 1.0 2.8 2.4 0.5 0.9 9.4 4.8 13.5 4.3 3.0 1.2 16.9 3.5 1.4 1.0 2.7 4.3 1.7 21.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.8 0.0 0.0 0.0 0.0 108.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 12.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 10.0 8.1 601.6 0.0 5.6 0.1 0.2 0.0 0.0 15.0 0.1 0.1 0.1 2.0 0.1 2.1 3.0 0.0 2.5 8.9 9.2 10.6 14.6 8.8 12.3 16.1 11.1 14.9 13.5 16.9 21.8 0.2 0.0 0.0 0.0 1.0 0.3 0.0 0.0 0.0 0.1 0.1 0.6 0.4 0.0 0.0 0.0 0.0 0.1 1.4 0.1 0.0 0.0 7.3 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.0 0.0 1.8 0.2 17.9 0.0 0.0 0.0 0.0 79.2 4.4 18.2 0.3 26.3 0.0 0.0 2.2 0.1 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.7 0.0 0.2 0.0 0.2 0.2 0.4 0.3 0.1 0.4 0.0 1.6 0.0 0.0 0.1 ARL11 "ARLTS1, FLJ33930" ENSG00000152213 "ADP ribosylation factor like GTPase 11" Q969Q4 13 49628507-49633872 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 6.9" "Cell type enhanced" "Detected in many" "B-cells: 18.2;Hofbauer cells: 31.3;Kupffer cells: 34.8;Macrophages: 18.2;monocytes: 19.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "neutrophil: 38.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "Daudi: 7.9;HMC-1: 10.7;NB-4: 11.1;THP-1: 14.5;U-698: 6.6;U-937: 6.3" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA040855, HPA040887" Uncertain Approved "Intermediate filaments,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Intermediate filaments, Cytosol" "HPA040855: AB_10793864, HPA040887: AB_10796229" "unprognostic (1.19e-2)" "unprognostic (2.27e-1)" "unprognostic (2.07e-1)" "unprognostic (2.82e-1)" "unprognostic (7.86e-2)" "unprognostic (1.46e-1)" "unprognostic (1.12e-2)" "unprognostic (1.83e-1)" "unprognostic (3.60e-1)" "unprognostic (1.82e-1)" "unprognostic (2.72e-2)" "unprognostic (2.55e-1)" "unprognostic (2.27e-4)" "unprognostic (1.72e-2)" "unprognostic (5.60e-2)" "unprognostic (1.16e-1)" "unprognostic (3.14e-2)" 0.8 0.8 0.5 3.9 0.5 3.5 0.7 0.6 0.7 0.6 0.8 1.0 1.2 0.2 0.2 1.0 0.3 1.1 0.4 0.4 0.6 0.1 0.6 2.2 6.9 1.0 0.7 0.2 0.1 0.3 0.3 1.9 0.8 0.2 1.5 0.1 0.6 0.2 0.3 0.6 1.9 0.7 0.7 4.8 0.6 0.3 1.0 3.7 0.4 0.4 3.9 1.3 0.8 1.2 0.1 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.6 0.0 7.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 2.1 0.1 0.6 0.0 5.2 10.7 0.1 0.1 0.0 0.0 0.0 0.4 5.1 0.3 0.1 0.0 1.3 4.9 11.1 0.1 0.0 0.0 5.3 0.0 2.2 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.1 3.5 14.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 6.6 0.0 6.3 0.0 21.8 15.3 16.3 0.1 17.9 0.2 7.9 0.3 0.3 8.1 10.1 0.8 0.4 38.0 0.8 13.4 8.6 0.3 4.4 0.5 0.5 0.6 0.7 0.4 0.6 1.0 0.7 0.8 0.7 1.0 1.2 0.9 0.0 1.1 0.0 18.2 0.3 0.3 0.2 1.2 0.7 1.0 0.9 0.6 2.8 0.0 0.0 0.0 4.7 3.4 1.7 0.0 0.0 1.7 0.1 0.1 1.2 1.2 6.9 0.0 0.0 5.1 0.3 0.0 0.1 7.6 0.0 1.8 0.6 31.3 0.0 0.0 3.4 0.0 34.8 3.5 1.3 0.3 18.2 0.0 3.7 19.2 0.3 1.0 0.0 0.1 0.1 10.2 0.0 2.9 0.1 4.2 0.1 2.3 0.5 0.0 0.3 0.2 1.5 0.3 4.1 0.0 1.5 1.2 0.5 3.1 0.4 CALHM6 "C6orf187, dJ93H18.5, FAM26F, INAM, OTTHUMP00000017061, OTTHUMP00000017062, RP1-93H18.5" ENSG00000188820 "Calcium homeostasis modulator family member 6" Q5R3K3 6 116461370-116463771 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 136.6" "Cell type enriched" "Detected in some" 5 "Hofbauer cells: 138.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "intermediate monocyte: 724.6;non-classical monocyte: 861.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 28.0;Karpas-707: 45.1;RPMI-8226: 159.8;U-937: 59.7" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" "unprognostic (1.14e-2)" "unprognostic (2.31e-2)" "unprognostic (6.46e-3)" "unprognostic (7.15e-3)" "unprognostic (9.53e-3)" "unprognostic (4.10e-2)" "unprognostic (2.69e-1)" "unprognostic (1.68e-1)" "unprognostic (8.19e-2)" "unprognostic (1.24e-1)" "unprognostic (4.19e-1)" "unprognostic (1.20e-1)" "prognostic unfavorable (9.31e-10)" "unprognostic (1.69e-1)" "unprognostic (2.12e-2)" "unprognostic (3.85e-3)" "unprognostic (9.25e-3)" 7.4 7.3 4.9 60.2 5.2 41.4 10.0 4.5 6.6 4.3 5.0 10.4 12.2 2.4 3.6 4.1 4.1 7.2 4.3 4.7 5.2 4.1 24.7 10.8 73.0 8.1 4.7 4.5 1.8 1.7 4.8 12.5 5.3 5.4 7.0 1.1 5.7 3.0 1.6 1.9 20.9 11.8 5.6 136.6 7.9 8.2 5.3 14.0 2.4 2.6 23.1 11.4 3.0 5.4 6.4 0.0 0.6 0.4 0.5 2.0 11.7 0.2 1.3 2.0 1.3 0.0 1.0 0.2 3.5 1.5 0.0 0.0 0.3 0.2 4.2 0.7 0.4 28.0 0.0 0.0 2.8 0.1 0.1 2.2 0.0 0.2 0.2 0.5 0.7 0.0 0.0 45.1 5.5 0.0 2.7 4.8 3.6 0.0 0.0 2.4 0.0 159.8 2.2 0.3 2.7 0.1 14.9 0.1 11.7 1.6 0.2 7.3 0.1 0.0 0.2 0.1 0.9 11.4 0.2 0.0 0.3 59.7 3.9 22.0 205.7 50.1 16.6 724.6 16.6 231.8 23.0 15.5 193.8 308.9 28.9 15.2 115.8 27.4 861.9 86.5 2.7 175.6 4.9 5.2 4.5 6.6 4.7 5.2 8.1 4.7 5.3 5.6 5.3 5.4 0.6 0.0 1.7 0.0 9.7 0.0 0.0 0.0 0.0 0.0 0.8 3.2 0.0 0.0 0.0 0.0 0.0 1.7 2.7 0.0 0.0 0.6 0.0 0.2 0.3 0.8 0.0 0.0 0.0 10.0 9.0 0.7 0.0 0.1 0.0 1.4 0.0 0.0 138.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.8 0.0 0.0 10.3 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.7 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 2.2 1.2 1.8 0.0 0.0 CD163 "M130, MM130, SCARI1" ENSG00000177575 "CD163 molecule" Q86VB7 12 7470811-7503893 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Acute phase, Inflammatory response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 240.5" "Cell type enriched" "Detected in many" 4 "Kupffer cells: 1756.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 11 "classical monocyte: 76.1;myeloid DC: 65.2" "Group enriched" "Detected in many" 40 "dendritic cells: 65.2;monocytes: 76.1" "Cell line enhanced" "Detected in some" "GAMG: 1.8;HSkMC: 1.7" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "CAB002432, HPA046404, HPA051974" Enhanced Supported "Plasma membrane" "Secreted to blood" NA NA 903000000 1600000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "CAB002432: AB_563510, HPA046404: AB_2679655, HPA051974: AB_2681678" "unprognostic (1.13e-1)" "unprognostic (2.13e-1)" "unprognostic (5.02e-3)" "unprognostic (2.72e-1)" "unprognostic (6.17e-3)" "unprognostic (2.09e-1)" "unprognostic (1.02e-1)" "unprognostic (1.21e-1)" "unprognostic (2.78e-1)" "prognostic unfavorable (7.27e-4)" "unprognostic (1.04e-1)" "unprognostic (6.50e-2)" "unprognostic (1.84e-2)" "unprognostic (8.77e-2)" "unprognostic (4.95e-2)" "unprognostic (1.61e-1)" "unprognostic (1.20e-2)" 171.8 85.6 6.1 152.5 7.0 17.6 50.8 5.2 18.4 25.6 21.5 48.7 12.4 27.3 3.6 16.4 68.1 43.5 52.7 4.9 7.9 27.3 89.7 131.7 54.4 15.8 10.9 23.1 21.4 8.8 11.4 109.4 18.0 15.5 21.6 4.3 25.9 7.2 11.4 15.3 52.9 130.4 7.2 240.5 35.6 9.7 55.9 18.7 17.2 17.6 7.2 68.5 16.3 10.3 0.0 0.0 0.0 0.0 0.6 0.3 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 1.7 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.3 76.1 0.5 0.1 6.4 0.0 0.0 0.0 0.1 65.2 0.0 0.0 0.0 1.7 0.0 0.0 1.0 0.1 20.1 6.1 7.0 5.2 18.4 4.9 7.9 15.8 10.9 18.0 7.2 55.9 10.3 2.7 3.2 8.3 0.0 3.8 1.5 0.2 0.0 0.0 0.1 0.1 0.3 4.6 7.2 5.0 0.0 2.1 1.5 0.5 0.0 0.0 0.0 4.3 0.0 0.1 13.9 0.0 3.6 0.4 0.0 1.9 3.0 0.5 0.0 5.1 0.1 17.9 13.9 269.9 0.0 0.5 0.0 0.0 1756.1 30.9 6.4 5.0 387.9 0.0 2.8 41.1 0.9 1.0 0.0 0.0 0.0 0.0 1.2 1.0 0.1 0.0 0.2 1.6 0.2 118.3 1.7 4.0 3.9 2.6 0.5 1.0 3.0 1.3 0.0 0.0 0.1 CD53 "MOX44, TSPAN25" ENSG00000143119 "CD53 molecule" P19397 1 110871188-110899922 "CD markers, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 448.3" "Cell type enhanced" "Detected in many" "B-cells: 310.0;dendritic cells: 375.0;Hofbauer cells: 365.7;Kupffer cells: 324.3;Macrophages: 294.8;NK-cells: 383.1;T-cells: 297.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 473.5;HDLM-2: 214.8;HMC-1: 298.4;Karpas-707: 188.1;U-266/70: 251.2;U-698: 149.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047216 Enhanced NA NA "Cluster 38: Basophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 4: Macrophages - Innate immune response" "HPA047216: AB_2679986" "unprognostic (2.93e-2)" "unprognostic (1.25e-2)" "unprognostic (7.45e-3)" "unprognostic (1.02e-3)" "unprognostic (8.88e-2)" "unprognostic (3.78e-2)" "unprognostic (2.96e-1)" "unprognostic (6.07e-2)" "unprognostic (2.83e-2)" "unprognostic (2.03e-1)" "unprognostic (5.09e-2)" "unprognostic (1.62e-1)" "prognostic unfavorable (2.60e-4)" "unprognostic (9.58e-2)" "unprognostic (4.95e-2)" "unprognostic (1.33e-1)" "unprognostic (7.72e-2)" 63.4 30.8 10.1 284.4 11.1 126.6 27.0 12.6 16.3 20.8 12.3 41.5 37.9 17.3 10.5 20.0 22.8 58.5 12.2 9.7 13.4 15.1 46.8 114.9 397.9 18.9 16.0 9.2 11.9 6.6 6.2 58.5 18.9 12.8 54.8 2.0 19.3 12.8 4.5 6.7 103.4 55.8 18.3 269.4 44.3 5.7 17.5 144.9 11.3 10.6 448.3 85.1 9.0 31.9 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 473.5 0.2 0.0 0.2 0.5 0.0 0.0 0.0 214.8 0.0 26.4 0.1 0.0 0.0 60.4 298.4 0.0 0.0 0.0 0.0 0.0 0.0 139.2 11.2 188.1 0.0 0.0 103.1 71.1 0.4 0.0 0.0 98.0 0.7 104.2 0.0 0.0 0.0 0.1 0.0 0.2 0.2 1.5 0.0 88.4 17.2 0.2 0.4 0.1 0.5 251.2 123.2 149.2 1.5 68.7 3.4 1483.0 779.5 479.0 732.4 808.6 658.1 794.0 527.8 649.2 631.9 745.1 377.9 552.5 1144.2 526.6 882.9 517.5 740.3 1621.0 10.1 11.1 12.6 16.3 9.7 13.4 18.9 16.0 18.9 18.3 17.5 31.9 4.2 16.0 24.4 0.7 310.0 7.0 0.6 0.0 0.6 0.0 2.3 5.1 1.0 5.7 8.6 1.8 0.0 2.1 375.0 0.2 0.0 0.5 0.4 0.4 0.5 13.0 0.0 42.9 5.8 0.2 5.4 6.7 7.1 0.6 162.2 0.0 16.4 6.7 365.7 0.0 1.4 0.3 0.0 324.3 161.5 1.9 2.1 294.8 39.2 69.3 156.3 0.1 383.1 1.0 0.6 0.3 0.1 0.4 134.0 0.3 0.0 1.6 4.4 0.6 6.6 1.9 1.8 0.1 0.6 1.1 5.5 4.1 297.0 0.0 0.2 0.3 CD86 "B7-2, B7.2, CD28LG2" ENSG00000114013 "CD86 molecule" P42081 3 122055362-122121139 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity" "Host cell receptor for virus entry, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 34.5" "Cell type enhanced" "Detected in many" "Hofbauer cells: 121.3;Kupffer cells: 107.8;Langerhans cells: 148.3;Macrophages: 151.8;Microglial cells: 78.7;monocytes: 489.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "classical monocyte: 79.9;intermediate monocyte: 79.0;memory B-cell: 41.0;myeloid DC: 78.8;naive B-cell: 28.5;non-classical monocyte: 85.2" "Group enriched" "Detected in many" 18 "B-cells: 41.0;dendritic cells: 78.8;monocytes: 85.2" "Cell line enriched" "Detected in some" 7 "HDLM-2: 296.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004319, HPA026802" Approved Supported "Plasma membrane,Centriolar satellite" NA NA 160000 "Cluster 7: Monocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "Plasma membrane" "Centriolar satellite" "CAB004319: AB_627200, HPA026802: " "unprognostic (1.81e-1)" "unprognostic (3.78e-3)" "unprognostic (3.04e-2)" "unprognostic (3.52e-2)" "unprognostic (1.36e-1)" "unprognostic (2.79e-1)" "unprognostic (1.15e-1)" "unprognostic (8.56e-2)" "unprognostic (7.72e-3)" "unprognostic (1.21e-1)" "unprognostic (1.28e-1)" "unprognostic (1.98e-1)" "prognostic unfavorable (9.83e-5)" "unprognostic (9.72e-2)" "unprognostic (1.70e-2)" "unprognostic (9.78e-2)" "unprognostic (8.67e-2)" 7.8 5.3 3.5 34.5 3.4 10.3 4.4 4.0 3.6 3.5 4.8 6.3 3.7 2.4 1.0 4.0 2.1 14.3 2.7 3.2 6.1 1.9 11.2 18.6 28.8 7.2 5.5 2.1 2.6 2.9 1.1 15.0 7.0 2.4 7.7 0.9 2.3 2.5 0.8 2.0 6.8 7.4 5.3 23.4 5.2 3.1 5.0 10.6 1.3 0.8 22.0 14.9 1.0 10.2 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 40.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 296.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 2.5 0.2 0.0 0.0 0.2 0.0 32.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.4 0.4 0.0 0.1 0.0 0.1 15.1 0.6 35.1 0.0 0.9 0.0 0.1 79.9 0.8 0.0 79.0 0.0 41.0 0.2 0.3 78.8 28.5 0.2 0.1 0.9 3.7 85.2 8.3 1.6 33.4 3.5 3.4 4.0 3.6 3.2 6.1 7.2 5.5 7.0 5.3 5.0 10.2 0.9 0.0 7.7 0.3 36.5 3.6 0.1 1.3 0.0 0.0 0.4 1.3 0.3 1.5 3.2 1.8 0.0 1.8 3.3 0.0 0.0 0.2 3.7 0.1 0.0 2.6 0.0 1.3 0.2 3.5 0.8 0.8 0.5 0.0 2.5 0.1 1.8 0.8 121.3 0.0 0.3 0.0 0.0 107.8 148.3 2.7 0.0 151.8 7.2 78.7 489.4 0.0 0.0 0.5 0.1 0.3 0.0 0.0 20.6 0.3 0.0 0.1 0.1 0.4 0.0 0.3 0.7 0.2 0.3 0.2 4.0 1.9 2.1 0.1 0.0 0.3 FCGR1A "CD64, CD64A" ENSG00000150337 "Fc fragment of IgG receptor Ia" P12314 1 149782671-149791675 "CD markers, FDA approved drug targets, Predicted membrane proteins" "Immunity, Innate immunity" "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 93.3;lymphoid tissue: 41.3" "Cell type enhanced" "Detected in some" "Hofbauer cells: 283.3;Kupffer cells: 140.9;Late spermatids: 64.9;Macrophages: 94.9" "Cancer enriched" "Detected in many" 4 "glioma: 10.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "classical monocyte: 131.5;intermediate monocyte: 54.7;myeloid DC: 35.6;neutrophil: 93.4" "Group enriched" "Detected in many" 53 "dendritic cells: 35.6;granulocytes: 93.4;monocytes: 131.5" "Cell line enriched" "Detected in some" 5 "THP-1: 191.6" "Low region specificity" "Detected in all" HPA026910 Uncertain "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "Golgi apparatus, Plasma membrane" "HPA026910: " "unprognostic (5.27e-2)" "unprognostic (2.89e-2)" "unprognostic (2.34e-2)" "unprognostic (7.97e-2)" "unprognostic (8.44e-3)" "unprognostic (1.73e-1)" "unprognostic (7.69e-2)" "unprognostic (1.04e-1)" "unprognostic (1.88e-2)" "unprognostic (1.72e-1)" "unprognostic (1.98e-2)" "unprognostic (6.18e-2)" "prognostic unfavorable (4.83e-8)" "unprognostic (1.28e-1)" "unprognostic (4.51e-2)" "unprognostic (9.99e-2)" "unprognostic (9.03e-2)" 12.2 7.2 8.4 41.3 8.9 17.9 3.6 8.8 12.8 4.2 8.4 2.3 1.1 1.6 93.3 1.7 1.8 8.2 2.2 8.6 9.4 2.8 4.2 28.6 14.4 14.6 10.6 2.3 4.3 2.7 2.5 32.6 13.0 1.6 2.1 2.3 1.9 2.4 0.3 0.4 1.3 19.1 13.2 12.5 2.1 3.7 12.2 1.4 1.4 0.8 0.8 14.7 0.8 18.9 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 13.3 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 41.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 1.0 0.0 0.0 0.1 0.3 191.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 24.4 0.0 2.0 131.5 1.6 0.0 54.7 0.7 1.6 0.0 0.3 35.6 0.0 0.0 0.1 93.4 0.0 11.8 0.9 0.3 48.5 8.4 8.9 8.8 12.8 8.6 9.4 14.6 10.6 13.0 13.2 12.2 18.9 0.3 0.0 3.1 0.0 0.8 0.1 0.0 0.0 0.6 1.5 0.2 0.8 1.7 1.5 1.3 0.0 2.1 2.7 0.0 0.0 0.0 0.0 30.8 0.1 0.1 9.3 0.0 2.7 0.1 0.0 1.3 1.0 0.0 0.1 0.0 0.2 1.8 0.5 283.3 0.0 0.1 0.0 0.0 140.9 6.0 64.9 0.3 94.9 0.0 7.5 34.7 0.3 0.0 0.5 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.2 0.7 1.3 6.6 0.2 0.3 0.6 0.4 0.1 0.0 4.1 0.6 0.1 0.1 0.0 FGD2 ZFYVE4 ENSG00000146192 "FYVE, RhoGEF and PH domain containing 2" Q7Z6J4 6 37005646-37029069 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 39.7" "Cell type enhanced" "Detected in many" "B-cells: 53.7;dendritic cells: 29.7;Kupffer cells: 118.2;Langerhans cells: 49.3;Macrophages: 52.0;Microglial cells: 43.1;monocytes: 51.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "classical monocyte: 22.3;intermediate monocyte: 64.8;memory B-cell: 23.2;myeloid DC: 35.0;naive B-cell: 18.6;non-classical monocyte: 70.5;plasmacytoid DC: 27.4" "Group enriched" "Detected in many" 18 "B-cells: 23.2;dendritic cells: 35.0;monocytes: 70.5" "Cell line enhanced" "Detected in some" "CAPAN-2: 2.7;Daudi: 11.5;HDLM-2: 11.3;U-698: 9.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA029145, HPA049692" Approved NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA029145: AB_10601321, HPA049692: AB_2680852" "unprognostic (3.54e-2)" "unprognostic (1.40e-4)" "unprognostic (5.69e-3)" "unprognostic (2.29e-1)" "unprognostic (1.27e-1)" "unprognostic (1.67e-4)" "unprognostic (7.97e-2)" "unprognostic (1.58e-2)" "unprognostic (2.47e-2)" "unprognostic (2.78e-1)" "unprognostic (3.39e-2)" "unprognostic (2.82e-1)" "unprognostic (1.15e-2)" "unprognostic (3.91e-1)" "unprognostic (1.02e-2)" "unprognostic (3.88e-1)" "unprognostic (7.10e-2)" 6.1 3.3 1.0 14.8 1.3 6.0 2.6 1.2 1.3 1.5 2.3 3.4 3.7 1.3 1.5 2.4 2.8 4.1 1.6 1.0 1.6 1.4 2.5 8.0 22.5 3.2 1.7 1.0 1.3 0.3 1.1 2.7 1.9 1.5 2.7 0.1 2.3 1.8 0.6 2.1 11.1 4.7 2.1 39.7 3.8 0.6 2.1 5.5 2.7 0.9 9.8 4.5 1.6 2.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 11.5 0.0 0.0 0.0 0.4 0.0 0.0 0.3 11.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.0 1.7 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.3 0.0 0.0 0.0 0.1 22.3 2.3 0.1 64.8 0.1 23.2 0.0 0.0 35.0 18.6 0.0 0.0 0.3 0.4 70.5 27.4 0.1 7.5 1.0 1.3 1.2 1.3 1.0 1.6 3.2 1.7 1.9 2.1 2.1 2.0 0.3 6.4 7.4 0.0 53.7 2.0 3.0 1.0 0.6 0.3 0.7 0.6 3.2 2.8 0.5 0.0 0.0 0.3 29.7 0.3 0.0 2.8 11.9 0.5 0.2 1.2 0.0 1.3 0.1 0.9 0.4 1.0 1.5 1.2 7.6 0.0 2.5 0.6 17.7 0.0 0.2 0.1 4.1 118.2 49.3 2.1 1.5 52.0 1.8 43.1 51.8 0.4 2.1 0.5 0.2 1.0 3.9 0.0 14.2 1.6 0.1 0.2 3.2 0.2 0.0 2.3 0.5 0.0 0.1 3.3 2.3 0.4 3.0 0.1 0.4 5.6 FLT3 "CD135, FLK2, STK1" ENSG00000122025 "Fms related receptor tyrosine kinase 3" P36888 13 28003274-28100592 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, RAS pathway related proteins" "Host-virus interaction" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.3;brain: 4.9;lymphoid tissue: 6.5" "Cell type enhanced" "Detected in some" "dendritic cells: 24.4;Inhibitory neurons: 59.9;Kupffer cells: 29.1;Langerhans cells: 21.4;Macrophages: 16.9;monocytes: 39.5" "Cancer enhanced" "Detected in some" "breast cancer: 1.8" "Region enhanced" "Detected in some" "cerebellum: 4.9" "Group enriched" "Detected in many" 13 "myeloid DC: 68.7;plasmacytoid DC: 26.2" "Lineage enriched" "Detected in many" 19 "dendritic cells: 68.7" "Group enriched" "Detected in some" 11 "REH: 42.5;THP-1: 26.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA047539 Approved "Endoplasmic reticulum" NA NA 210000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 14: REH - Unknown function" "Cluster 41: Macrophages - Immune response" "Endoplasmic reticulum" "HPA047539: AB_2680080" "unprognostic (2.19e-3)" "unprognostic (3.16e-3)" "unprognostic (6.54e-3)" "unprognostic (9.96e-2)" "unprognostic (3.88e-1)" "unprognostic (3.96e-7)" "unprognostic (7.99e-3)" "unprognostic (1.65e-2)" "unprognostic (5.37e-2)" "unprognostic (1.01e-2)" "unprognostic (1.96e-1)" "unprognostic (1.03e-1)" "unprognostic (4.56e-2)" "unprognostic (3.65e-1)" "unprognostic (3.91e-2)" "unprognostic (2.51e-1)" "unprognostic (2.22e-1)" 0.5 0.1 0.3 3.0 0.2 5.3 1.5 4.9 0.8 0.5 0.1 0.7 0.3 0.2 0.1 0.6 0.4 1.6 0.1 0.2 0.5 1.5 0.5 0.7 6.5 1.3 0.9 0.1 2.8 0.0 0.0 0.0 1.7 0.1 0.8 0.0 0.4 0.2 0.0 0.7 1.6 0.8 0.8 5.7 0.6 0.6 0.8 4.7 0.1 0.3 3.6 1.3 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 3.2 0.6 0.0 0.0 42.5 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 26.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 3.6 3.4 0.0 0.8 0.0 0.2 0.0 0.0 68.7 0.0 0.0 0.0 0.1 2.0 0.0 26.2 0.0 2.7 0.3 0.2 4.9 0.8 0.2 0.5 1.3 0.9 1.7 0.8 0.8 0.8 0.0 0.0 0.0 2.3 1.5 0.3 0.0 0.0 0.0 0.0 1.5 1.0 0.4 1.5 0.0 0.0 0.0 0.0 24.4 0.0 0.0 2.7 3.7 0.3 0.1 0.2 0.0 8.2 7.4 0.0 0.0 0.2 0.0 1.1 0.0 0.0 0.7 0.1 0.5 0.0 59.9 0.0 0.0 29.1 21.4 2.3 0.0 16.9 1.8 1.9 39.5 0.0 0.0 1.5 4.2 0.1 0.0 0.0 2.2 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.2 0.6 0.0 0.6 0.0 1.7 0.0 0.0 0.0 FPR3 "FMLPY, FPRH1, FPRL2, RMLP-R-I" ENSG00000187474 "Formyl peptide receptor 3" P25089 19 51795157-51826190 "G-protein coupled receptors, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 28.2" "Group enriched" "Detected in some" 15 "Hofbauer cells: 56.5;Kupffer cells: 97.4;Langerhans cells: 223.6;Macrophages: 66.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 20 "classical monocyte: 2.3;intermediate monocyte: 6.7;myeloid DC: 2.4" "Group enriched" "Detected in many" 44 "dendritic cells: 2.4;monocytes: 6.7" "Group enriched" "Detected in some" 5 "HEL: 10.0;hTERT-RPE1: 2.7" "Not detected" "Not detected" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 36: HEL - Hemostasis" "Cluster 4: Macrophages - Innate immune response" "unprognostic (3.77e-2)" "unprognostic (1.54e-1)" "unprognostic (1.79e-2)" "unprognostic (1.29e-1)" "unprognostic (1.15e-1)" "unprognostic (1.84e-1)" "unprognostic (8.41e-2)" "unprognostic (1.39e-1)" "unprognostic (1.37e-2)" "unprognostic (7.14e-2)" "unprognostic (3.17e-1)" "unprognostic (9.37e-2)" "unprognostic (1.02e-3)" "unprognostic (1.59e-1)" "prognostic unfavorable (9.13e-4)" "unprognostic (1.96e-1)" "unprognostic (4.28e-2)" 10.6 12.1 0.6 23.9 1.1 0.4 5.3 0.5 2.4 5.5 2.2 12.6 11.2 3.7 1.5 5.7 2.0 18.8 3.8 0.6 0.7 3.2 21.3 28.2 13.9 3.1 1.0 1.7 2.3 2.2 0.9 5.6 2.8 2.5 18.2 0.3 2.4 2.9 0.9 2.7 14.4 8.9 1.2 16.3 7.1 2.7 6.0 8.1 2.2 2.0 11.0 17.4 1.2 3.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.3 0.0 0.0 6.7 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.5 0.6 1.1 0.5 2.4 0.6 0.7 3.1 1.0 2.8 1.2 6.0 3.9 0.5 0.0 1.7 0.3 2.7 5.6 0.0 0.0 0.0 0.1 0.1 0.5 0.2 0.0 2.5 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.3 0.0 0.4 0.8 0.0 0.0 0.0 0.0 1.1 1.5 56.5 0.0 0.2 0.0 0.0 97.4 223.6 0.2 0.3 66.6 7.2 1.0 3.7 0.0 0.0 0.0 0.7 0.0 0.0 1.2 0.4 0.1 0.0 0.0 1.5 0.1 0.0 0.3 0.5 0.0 0.1 0.4 4.5 0.8 0.6 0.0 0.0 0.1 GPR34 ENSG00000171659 "G protein-coupled receptor 34" Q9UPC5 X 41688973-41697275 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 42.7" "Cell type enhanced" "Detected in many" "Hofbauer cells: 251.4;Kupffer cells: 173.3;Macrophages: 100.6;Microglial cells: 54.4" "Cancer enhanced" "Detected in all" "glioma: 26.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "basophil: 339.6;eosinophil: 117.9" "Lineage enriched" "Detected in many" 24 "granulocytes: 339.6" "Cell line enhanced" "Detected in single" "HMC-1: 1.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010668, CAB025490" Uncertain Approved Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Cytosol "CAB025490: , HPA010668: AB_1849294" "unprognostic (1.26e-2)" "unprognostic (1.08e-1)" "unprognostic (1.43e-2)" "unprognostic (1.44e-2)" "unprognostic (1.20e-1)" "unprognostic (3.74e-2)" "unprognostic (5.83e-3)" "unprognostic (5.13e-2)" "unprognostic (1.59e-2)" "unprognostic (9.81e-3)" "unprognostic (7.19e-2)" "unprognostic (1.74e-1)" "unprognostic (3.96e-1)" "unprognostic (2.72e-3)" "unprognostic (1.14e-1)" "unprognostic (1.88e-3)" "unprognostic (3.18e-2)" 28.2 17.1 5.2 15.1 5.2 0.9 21.5 6.1 5.8 14.0 5.6 12.0 6.5 6.7 2.7 8.2 7.8 17.0 8.3 5.0 7.6 5.0 8.5 10.9 20.0 10.6 7.9 7.3 5.4 5.3 1.4 42.7 11.4 3.2 13.1 0.6 3.6 8.8 0.8 1.0 14.6 16.3 9.9 15.6 7.8 2.7 9.7 6.9 3.7 4.6 16.7 13.3 1.7 18.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.0 339.6 9.7 117.9 0.0 12.9 0.4 1.5 0.4 0.1 2.0 1.2 0.1 0.3 1.1 14.3 7.0 0.3 0.6 2.8 5.2 5.2 6.1 5.8 5.0 7.6 10.6 7.9 11.4 9.9 9.7 18.8 0.9 0.0 2.8 1.0 2.0 0.6 0.2 0.0 0.0 0.0 0.5 2.3 1.2 0.0 0.0 0.0 0.0 1.4 0.4 0.0 0.0 0.0 0.6 0.1 0.1 5.0 1.2 0.4 0.7 0.0 1.6 1.0 0.5 0.0 37.3 0.0 2.9 0.8 251.4 0.0 0.9 0.0 0.0 173.3 13.6 1.9 0.9 100.6 1.8 54.4 7.1 0.1 1.0 3.5 0.0 0.0 0.0 0.4 0.6 0.1 0.0 0.1 0.0 0.8 19.7 0.6 0.3 0.0 0.2 0.4 1.0 2.5 7.2 0.1 0.1 0.0 HCK JTK9 ENSG00000101336 "HCK proto-oncogene, Src family tyrosine kinase" P08631 20 32052197-32101856 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Exocytosis, Host-virus interaction, Immunity, Inflammatory response, Innate immunity, Phagocytosis" "Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 112.1" "Cell type enhanced" "Detected in many" "Hofbauer cells: 150.7;Kupffer cells: 155.5;Langerhans cells: 89.2;Macrophages: 170.1;Microglial cells: 52.5;monocytes: 222.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "classical monocyte: 575.0;eosinophil: 707.8;intermediate monocyte: 1059.1;myeloid DC: 336.3;neutrophil: 801.3;non-classical monocyte: 1251.7" "Group enriched" "Detected in all" 16 "dendritic cells: 336.3;granulocytes: 801.3;monocytes: 1251.7" "Group enriched" "Detected in some" 9 "THP-1: 69.3;U-937: 199.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB005195, HPA035534, HPA063768" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "Plasma membrane, Cytosol" "CAB005195: AB_631619, HPA035534: , HPA063768: AB_2685118" "unprognostic (6.22e-2)" "unprognostic (6.16e-3)" "unprognostic (2.26e-2)" "unprognostic (7.98e-2)" "unprognostic (8.83e-2)" "unprognostic (5.50e-2)" "unprognostic (4.09e-2)" "unprognostic (1.72e-2)" "unprognostic (4.34e-2)" "unprognostic (1.59e-1)" "unprognostic (4.08e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (1.66e-4)" "unprognostic (4.92e-2)" "unprognostic (4.42e-2)" "unprognostic (6.95e-2)" "unprognostic (1.12e-1)" 24.8 9.2 4.7 100.0 5.0 55.2 6.0 5.5 6.0 5.5 13.7 12.8 15.2 3.1 2.6 6.7 7.6 14.4 4.8 4.7 6.2 4.7 14.1 46.0 38.6 9.9 6.8 2.5 4.5 2.1 3.1 20.9 8.3 4.0 13.6 0.5 5.1 4.7 1.6 5.8 17.8 25.3 8.1 112.1 6.7 2.3 8.4 14.5 2.8 6.9 39.3 32.8 4.1 12.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.9 0.0 0.1 0.1 1.3 0.0 0.0 0.1 0.0 4.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 15.6 0.0 0.1 0.1 4.9 0.4 0.0 0.0 0.4 0.2 0.6 0.0 0.0 0.3 0.0 0.5 0.0 0.2 0.7 0.0 69.3 0.0 0.0 0.3 0.0 0.1 1.9 0.3 10.3 0.0 199.6 0.0 6.4 575.0 707.8 1.1 1059.1 1.3 48.4 1.1 1.1 336.3 43.0 1.1 0.9 801.3 11.0 1251.7 30.4 1.2 566.4 4.7 5.0 5.5 6.0 4.7 6.2 9.9 6.8 8.3 8.1 8.4 12.0 0.6 6.4 14.0 0.0 17.1 3.1 4.0 0.2 0.6 0.1 0.4 1.3 2.0 1.5 3.9 7.3 0.0 0.9 12.1 0.2 1.9 0.1 2.5 0.1 0.1 3.7 1.8 1.7 1.2 0.6 0.9 1.3 4.6 0.1 6.3 0.1 1.1 2.3 150.7 0.0 1.0 0.5 22.4 155.5 89.2 0.3 0.0 170.1 1.8 52.5 222.0 0.0 4.1 1.5 0.6 0.0 0.0 0.0 0.7 0.5 0.1 0.3 1.5 0.1 0.0 0.6 0.5 0.2 0.3 0.2 1.1 1.6 3.0 0.2 0.9 3.7 HCLS1 "CTTNL, HS1" ENSG00000180353 "Hematopoietic cell-specific Lyn substrate 1" P14317 3 121631399-121660927 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 153.6;lymphoid tissue: 300.3" "Cell type enhanced" "Detected in many" "B-cells: 175.7;Kupffer cells: 666.3;Macrophages: 269.0;monocytes: 245.7;NK-cells: 216.3;T-cells: 181.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 265.6;HMC-1: 362.3;RPMI-8226: 256.5;THP-1: 262.8;U-266/70: 361.6;U-698: 371.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019143 Enhanced Supported "Plasma membrane,Cytosol" NA NA 870000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Cytosol" "HPA019143: AB_1850532" "unprognostic (2.27e-2)" "unprognostic (1.79e-3)" "unprognostic (5.38e-3)" "unprognostic (6.29e-2)" "unprognostic (1.01e-2)" "unprognostic (4.02e-3)" "unprognostic (2.35e-1)" "unprognostic (4.88e-3)" "unprognostic (1.70e-2)" "unprognostic (1.19e-1)" "unprognostic (6.76e-2)" "unprognostic (2.28e-1)" "unprognostic (1.03e-3)" "unprognostic (2.93e-1)" "unprognostic (3.46e-2)" "unprognostic (2.60e-2)" "unprognostic (2.01e-1)" 67.0 32.9 14.6 147.2 14.7 153.6 25.5 15.4 18.7 20.7 15.8 29.2 21.2 13.7 6.4 15.7 21.5 37.8 18.4 14.3 17.0 21.5 39.1 52.7 207.6 21.6 17.5 9.4 11.9 7.7 14.6 51.4 20.8 15.8 31.4 2.3 16.0 11.1 7.3 11.1 68.7 34.6 18.5 300.3 27.1 4.5 18.2 140.3 15.4 18.8 242.8 53.0 13.7 23.0 0.8 0.0 0.2 0.1 20.9 11.5 5.7 4.1 4.0 0.8 1.6 0.1 0.0 265.6 124.6 0.0 0.2 0.3 6.9 9.9 1.1 120.6 0.0 172.6 0.0 0.0 11.6 192.4 362.3 2.2 0.5 0.0 1.5 0.0 153.4 106.2 35.1 235.9 0.0 0.0 137.9 162.9 0.3 0.2 4.5 137.1 0.2 256.5 0.0 68.0 0.3 0.2 0.2 0.4 0.6 0.6 0.1 262.8 203.5 0.0 2.0 0.3 0.9 361.6 118.1 371.5 1.9 181.5 0.2 357.3 713.1 1180.9 405.3 870.4 333.0 345.7 334.2 376.8 636.2 313.1 279.3 326.2 1619.2 280.0 997.1 197.4 494.2 1427.9 14.6 14.7 15.4 18.7 14.3 17.0 21.6 17.5 20.8 18.5 18.2 23.0 23.0 9.6 31.8 1.0 175.7 3.2 1.0 7.8 0.6 0.5 2.7 5.1 2.3 4.3 13.1 0.0 0.0 122.4 139.5 0.8 0.0 0.3 1.1 8.8 1.6 23.3 0.0 50.5 1.4 0.2 60.0 7.0 8.6 3.1 73.4 0.7 27.8 7.7 126.9 0.0 0.7 0.4 4.1 666.3 105.8 1.5 3.4 269.0 19.6 26.2 245.7 0.4 216.3 0.5 0.3 0.2 0.2 1.2 148.6 0.4 0.1 0.9 24.7 0.8 13.1 3.7 6.7 0.6 0.6 1.3 4.4 145.4 181.4 2.4 0.5 2.2 LAPTM5 ENSG00000162511 "Lysosomal protein transmembrane 5" Q13571 1 30732469-30757774 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 1285.7;lymphoid tissue: 672.2" "Group enriched" "Detected in many" 4 "B-cells: 872.9;dendritic cells: 340.2;granulocytes: 639.8;Hofbauer cells: 1150.4;Kupffer cells: 942.2;Langerhans cells: 489.6;Macrophages: 925.0;monocytes: 446.1;NK-cells: 562.3;T-cells: 432.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 554.0;HEL: 1053.2;HL-60: 676.4;HMC-1: 2382.4;REH: 785.2;U-698: 898.1;U-937: 542.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051293 Approved Approved Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" Cytosol "HPA051293: AB_2681424" "unprognostic (3.12e-2)" "prognostic favorable (3.40e-4)" "unprognostic (6.86e-2)" "unprognostic (4.05e-3)" "unprognostic (1.63e-1)" "unprognostic (8.45e-2)" "unprognostic (1.43e-1)" "unprognostic (3.76e-1)" "unprognostic (1.22e-3)" "unprognostic (2.30e-1)" "unprognostic (6.75e-2)" "unprognostic (1.60e-1)" "prognostic unfavorable (5.89e-5)" "unprognostic (9.47e-2)" "unprognostic (8.18e-3)" "unprognostic (5.98e-2)" "unprognostic (3.94e-2)" 144.7 82.1 47.6 443.0 49.7 1285.7 60.4 49.7 90.4 53.1 55.7 82.2 68.1 27.3 16.7 49.5 46.8 137.9 31.6 45.2 62.7 30.5 98.6 284.9 672.2 82.4 67.3 16.4 30.2 21.8 22.6 145.2 75.8 31.5 90.6 5.9 38.5 30.9 9.2 24.0 155.9 93.5 69.2 491.1 72.9 10.9 81.1 298.3 38.5 20.9 636.5 161.1 22.8 114.9 1.2 0.0 1.7 0.0 0.1 0.1 0.6 0.9 0.3 0.5 0.1 0.7 1.2 554.0 56.0 1.7 1.9 2.2 0.0 0.8 0.5 62.3 0.0 1053.2 0.0 1.6 0.9 676.4 2382.4 0.6 1.2 0.6 4.1 0.3 124.2 70.7 13.8 34.0 8.8 0.0 117.5 142.2 0.7 0.0 0.0 785.2 99.6 391.6 0.8 0.1 0.6 0.4 1.3 1.3 1.1 1.0 0.5 422.2 145.3 0.6 3.0 0.6 3.4 2.7 0.7 898.1 3.1 542.8 1.8 1094.2 1522.8 1446.7 538.5 1046.1 616.3 823.6 485.5 502.8 825.7 1089.4 481.2 481.2 1709.5 327.0 1075.7 392.7 656.9 2740.4 47.6 49.7 49.7 90.4 45.2 62.7 82.4 67.3 75.8 69.2 81.1 114.9 62.9 25.6 100.4 0.0 872.9 23.8 1.1 1.3 4.0 0.0 6.2 10.4 5.5 14.3 13.9 3.7 0.0 5.8 340.2 0.8 0.0 1.2 2.0 1.4 0.9 60.2 1.2 78.2 0.2 0.7 8.4 12.3 10.2 1.1 639.8 0.2 47.2 9.4 1150.4 0.0 0.8 0.9 0.0 942.2 489.6 4.9 1.5 925.0 49.8 43.1 446.1 0.3 562.3 0.5 0.5 1.4 0.2 0.4 144.8 0.9 0.5 3.0 11.4 1.3 0.0 4.1 5.6 0.3 1.1 1.8 20.0 8.9 432.7 18.2 2.4 1.9 LRRC25 "FLJ38116, MAPA" ENSG00000175489 "Leucine rich repeat containing 25" Q8N386 19 18391137-18397622 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 32.4;lymphoid tissue: 61.2" "Group enriched" "Detected in some" 6 "Hofbauer cells: 47.0;Kupffer cells: 123.6;Macrophages: 90.0;monocytes: 74.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "classical monocyte: 320.6;eosinophil: 356.2;intermediate monocyte: 512.1;myeloid DC: 229.3;neutrophil: 573.0;non-classical monocyte: 706.7" "Group enriched" "Detected in all" 60 "dendritic cells: 229.3;granulocytes: 573.0;monocytes: 706.7" "Cell line enhanced" "Detected in some" "Hep G2: 1.0;HMC-1: 1.8;THP-1: 1.7;U-937: 1.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA029459 Approved Approved "Endoplasmic reticulum,Microtubules,Cytosol" NA NA 630000 "Cluster 51: Monocytes - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Endoplasmic reticulum, Microtubules, Cytosol" "HPA029459: AB_10610005" "unprognostic (2.72e-2)" "unprognostic (6.08e-2)" "unprognostic (1.76e-2)" "unprognostic (2.07e-1)" "unprognostic (3.77e-2)" "unprognostic (9.15e-2)" "unprognostic (5.80e-2)" "unprognostic (1.23e-1)" "unprognostic (1.20e-2)" "unprognostic (4.63e-2)" "unprognostic (2.02e-1)" "unprognostic (1.73e-1)" "unprognostic (1.19e-3)" "unprognostic (5.77e-2)" "prognostic unfavorable (6.93e-4)" "unprognostic (1.74e-1)" "unprognostic (1.14e-1)" 9.4 9.4 2.4 21.8 2.5 32.4 3.1 3.3 2.9 1.8 3.2 3.3 3.7 1.6 0.7 2.3 3.9 5.3 2.5 2.3 3.1 2.4 5.9 11.5 9.9 4.6 4.0 1.5 2.0 0.7 1.2 5.4 4.2 2.0 2.8 0.3 2.6 1.2 3.7 1.0 4.8 6.7 2.8 61.2 2.3 1.2 5.4 3.0 1.2 8.7 4.0 7.0 1.3 4.7 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.7 0.3 1.0 0.8 0.4 1.8 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.4 0.2 0.1 0.0 0.1 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 1.7 0.4 0.2 0.1 0.1 0.1 0.1 0.0 0.0 0.2 1.5 0.1 55.4 320.6 356.2 0.9 512.1 1.9 7.3 0.6 0.7 229.3 8.4 0.5 0.6 573.0 4.6 706.7 32.1 1.3 229.2 2.4 2.5 3.3 2.9 2.3 3.1 4.6 4.0 4.2 2.8 5.4 4.7 0.7 0.0 1.3 0.0 5.0 0.0 0.1 0.1 0.0 0.1 0.3 1.0 0.3 0.0 0.7 0.0 0.0 0.1 2.9 0.1 5.9 0.1 1.9 0.2 0.1 0.9 0.0 2.1 0.1 0.0 0.4 0.5 0.0 0.4 10.2 0.0 1.8 0.5 47.0 0.0 0.1 0.0 0.0 123.6 12.5 0.5 0.0 90.0 1.8 1.0 74.9 0.0 6.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 2.4 0.2 0.0 0.2 0.0 0.1 0.4 1.1 0.2 0.1 0.1 LY86 "dJ80N2.1, MD-1" ENSG00000112799 "Lymphocyte antigen 86" O95711 6 6588108-6654983 "Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 78.4" "Group enriched" "Detected in many" 9 "B-cells: 124.9;Hofbauer cells: 191.7;Kupffer cells: 199.1;Langerhans cells: 118.6;Macrophages: 149.8;Microglial cells: 105.9;monocytes: 155.6" "Cancer enhanced" "Detected in all" "glioma: 22.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 426.6;myeloid DC: 426.1" "Group enriched" "Detected in all" 43 "B-cells: 335.1;dendritic cells: 426.1;monocytes: 426.6" "Cell line enhanced" "Detected in some" "Daudi: 69.5;NB-4: 44.7;RPMI-8226: 245.0;THP-1: 103.8;U-937: 45.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB025000, HPA044895" Approved "Secreted to blood" NA NA 77000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 57: B-cells - Immune response" "CAB025000: , HPA044895: AB_2679138" "unprognostic (1.82e-1)" "unprognostic (2.49e-3)" "unprognostic (2.01e-2)" "unprognostic (7.88e-2)" "unprognostic (2.15e-1)" "unprognostic (1.93e-1)" "unprognostic (2.53e-1)" "unprognostic (1.46e-3)" "unprognostic (3.52e-2)" "unprognostic (3.17e-1)" "unprognostic (1.69e-1)" "unprognostic (1.16e-1)" "unprognostic (5.82e-2)" "unprognostic (1.17e-1)" "prognostic unfavorable (5.61e-4)" "unprognostic (1.11e-1)" "unprognostic (4.20e-2)" 9.7 10.3 14.0 30.9 13.5 29.2 7.4 14.7 22.0 8.2 14.2 7.6 4.9 3.8 2.8 3.1 4.3 14.6 2.9 13.5 15.8 3.1 13.3 29.7 72.1 17.8 15.4 3.3 3.0 3.4 2.3 14.5 18.7 3.8 11.1 1.2 5.5 6.2 0.7 3.4 16.8 11.1 17.8 52.7 6.2 1.8 18.0 15.1 1.5 1.1 78.4 15.6 1.1 24.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 69.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 44.7 0.0 0.0 0.0 8.0 0.0 245.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 103.8 0.2 0.0 0.1 0.0 0.0 0.0 0.0 30.3 0.0 45.8 0.0 4.1 426.6 3.5 1.0 234.9 0.7 335.1 1.1 1.1 426.1 248.8 4.7 2.7 9.1 5.3 88.3 16.3 1.8 221.1 14.0 13.5 14.7 22.0 13.5 15.8 17.8 15.4 18.7 17.8 18.0 24.8 1.2 0.0 15.0 1.6 124.9 2.0 0.0 0.0 0.0 0.0 0.9 3.7 1.5 1.5 1.3 0.0 0.0 1.4 9.8 0.0 0.0 0.0 3.4 0.4 0.1 5.4 0.0 3.8 3.8 0.0 1.8 2.1 0.0 0.0 1.3 0.0 4.2 1.3 191.7 0.0 0.6 0.3 0.0 199.1 118.6 15.4 0.3 149.8 0.0 105.9 155.6 0.0 4.1 0.5 0.2 0.0 0.0 0.0 1.2 0.0 0.0 0.2 0.7 0.4 6.6 0.4 0.2 5.3 0.2 0.3 2.4 1.9 3.6 0.0 0.2 0.2 MS4A4A "CD20L1, MS4A4, MS4A7" ENSG00000110079 "Membrane spanning 4-domains A4A" Q96JQ5 11 60185657-60318080 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 63.1" "Group enriched" "Detected in many" 7 "Hofbauer cells: 376.8;Kupffer cells: 445.0;Macrophages: 264.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "intermediate monocyte: 61.2;myeloid DC: 27.6;non-classical monocyte: 82.9;plasmacytoid DC: 27.7" "Group enriched" "Detected in many" 30 "dendritic cells: 27.7;monocytes: 82.9" "Cell line enhanced" "Detected in some" "HEL: 35.6;HMC-1: 45.8;K-562: 154.9" HPA029323 Approved NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 1: K-562 - Erythropoiesis" "Cluster 4: Macrophages - Innate immune response" "HPA029323: AB_10601866" "unprognostic (7.93e-2)" "unprognostic (2.05e-2)" "unprognostic (1.37e-3)" "unprognostic (1.98e-1)" "unprognostic (4.46e-2)" "unprognostic (2.31e-1)" "unprognostic (9.66e-2)" "unprognostic (1.59e-1)" "unprognostic (4.56e-1)" "unprognostic (6.65e-2)" "unprognostic (8.10e-2)" "unprognostic (2.11e-1)" "unprognostic (5.02e-3)" "unprognostic (3.32e-2)" "unprognostic (4.66e-2)" "unprognostic (4.89e-2)" "unprognostic (4.21e-2)" 42.8 24.7 3.5 16.5 3.6 6.1 12.3 3.7 8.6 14.1 4.4 14.0 5.2 4.9 3.4 8.9 11.6 25.8 8.4 3.5 3.9 4.8 15.4 28.0 31.3 4.2 3.4 4.1 4.0 3.3 3.3 63.1 3.6 3.4 16.1 2.0 7.6 4.9 2.3 2.9 13.5 20.0 2.5 33.3 6.6 3.0 5.5 11.5 3.7 10.4 7.5 28.0 3.3 4.3 0.3 0.1 0.1 0.6 0.0 0.2 0.7 0.6 0.0 0.2 0.4 0.3 0.9 0.8 0.4 0.0 0.4 0.3 0.5 0.1 0.6 1.6 0.0 35.6 0.7 0.6 0.1 1.2 45.8 0.4 0.3 0.2 0.8 0.2 0.0 0.4 154.9 4.2 0.6 0.7 0.6 0.9 0.7 0.3 0.1 0.7 0.0 2.5 0.1 1.5 0.5 0.5 0.3 0.3 0.1 0.7 0.7 8.9 0.8 1.5 0.6 0.4 0.2 6.0 0.7 0.5 0.2 0.8 0.2 0.1 9.9 0.0 0.1 61.2 0.2 1.0 0.1 0.1 27.6 0.3 0.2 0.1 0.9 1.8 82.9 27.7 0.1 6.0 3.5 3.6 3.7 8.6 3.5 3.9 4.2 3.4 3.6 2.5 5.5 4.3 2.3 0.0 7.9 0.0 3.0 1.8 0.1 0.0 0.6 0.0 0.3 2.2 3.4 2.8 2.5 0.0 0.0 1.8 7.5 0.0 0.0 0.0 0.7 0.0 0.0 5.7 0.0 13.0 0.1 0.0 2.0 1.6 0.0 0.0 7.6 0.0 47.5 4.6 376.8 0.0 0.1 0.0 0.0 445.0 24.9 1.0 0.9 264.6 3.6 10.3 8.3 0.4 0.0 0.0 0.2 0.2 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.1 13.1 1.2 1.1 0.1 0.2 0.7 1.8 3.6 1.5 0.1 0.0 0.1 MS4A6A "CD20L3, MS4A6" ENSG00000110077 "Membrane spanning 4-domains A6A" Q9H2W1 11 60172014-60184666 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 580.8;Hofbauer cells: 376.8;Kupffer cells: 1649.6;Langerhans cells: 470.0;Macrophages: 675.9;monocytes: 429.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 8 "basophil: 406.4;classical monocyte: 1095.3;intermediate monocyte: 345.6;myeloid DC: 638.8;plasmacytoid DC: 454.4" "Group enriched" "Detected in all" 74 "dendritic cells: 638.8;granulocytes: 406.4;monocytes: 1095.3" "Cell line enriched" "Detected in some" 8 "THP-1: 47.9" "HPA011391, HPA076623" Approved Approved Vesicles NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA011391: AB_10603876, HPA076623: AB_2686809" "unprognostic (1.17e-1)" "prognostic favorable (6.33e-4)" "unprognostic (2.35e-2)" "unprognostic (1.21e-2)" "unprognostic (1.00e-1)" "unprognostic (8.51e-2)" "unprognostic (2.33e-1)" "unprognostic (3.75e-2)" "unprognostic (3.61e-1)" "unprognostic (1.76e-1)" "unprognostic (1.91e-1)" "unprognostic (3.20e-1)" "unprognostic (4.75e-3)" "unprognostic (1.06e-1)" "unprognostic (4.66e-2)" "unprognostic (3.94e-2)" "unprognostic (2.97e-2)" 72.6 42.3 10.7 57.5 10.9 33.5 40.0 10.8 22.5 28.1 14.7 41.0 27.8 14.3 9.6 25.7 16.8 61.4 22.8 10.0 11.8 11.5 108.6 56.4 109.1 15.8 13.7 12.3 7.8 8.7 9.8 65.2 14.8 12.4 54.9 1.4 16.0 18.3 5.3 7.3 45.1 52.6 12.4 121.5 24.5 7.8 13.6 32.2 10.0 17.7 47.6 59.9 8.6 17.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 1.3 0.2 0.0 0.0 0.0 0.0 0.0 4.1 0.0 5.7 0.0 0.0 0.0 0.0 4.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 47.9 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 4.1 0.0 406.4 1095.3 8.2 1.6 345.6 3.4 9.6 2.2 1.4 638.8 1.5 1.0 1.0 72.8 2.1 24.4 454.4 1.9 752.8 10.7 10.9 10.8 22.5 10.0 11.8 15.8 13.7 14.8 12.4 13.6 17.6 5.3 6.4 22.9 0.0 16.1 9.3 0.6 0.0 1.2 0.3 2.2 8.0 3.3 17.2 2.5 3.7 0.0 2.0 220.6 0.3 0.0 0.0 2.2 0.4 0.2 12.8 0.0 43.9 0.1 0.0 2.7 4.3 2.6 0.2 13.9 0.1 580.8 20.5 376.8 0.0 0.1 0.1 0.0 1649.6 470.0 5.1 1.5 675.9 14.2 40.3 429.2 0.0 11.3 0.5 0.1 0.0 1.2 0.0 2.0 0.2 0.0 0.5 1.5 0.6 46.0 3.0 4.4 0.5 1.1 2.4 8.0 2.1 10.4 0.1 0.2 0.3 MS4A7 "CD20L4, CFFM4, MS4A8" ENSG00000166927 "Membrane spanning 4-domains A7" Q9GZW8 11 60378485-60395951 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 196.6" "Cell type enhanced" "Detected in many" "Hofbauer cells: 311.4;Kupffer cells: 1060.3;Macrophages: 567.5;monocytes: 184.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "intermediate monocyte: 747.4;non-classical monocyte: 1486.0" "Lineage enriched" "Detected in many" 12 "monocytes: 1486.0" "Cell line enriched" "Detected in some" 25 "THP-1: 114.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA017418, CAB026387" Approved NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "CAB026387: , HPA017418: AB_1854137" "unprognostic (1.43e-1)" "unprognostic (2.60e-3)" "unprognostic (3.24e-2)" "unprognostic (9.67e-2)" "unprognostic (2.04e-1)" "unprognostic (1.81e-1)" "unprognostic (1.04e-1)" "unprognostic (9.51e-2)" "unprognostic (3.02e-2)" "unprognostic (4.85e-2)" "unprognostic (5.79e-2)" "unprognostic (1.90e-1)" "unprognostic (1.43e-2)" "unprognostic (4.59e-2)" "unprognostic (3.90e-2)" "unprognostic (1.18e-1)" "unprognostic (1.03e-1)" 46.9 37.6 6.3 50.9 5.0 10.7 30.7 4.5 13.7 18.2 13.9 21.4 17.6 7.6 4.1 12.7 6.6 46.8 9.9 4.2 8.7 8.0 66.5 75.7 23.2 12.8 10.4 6.0 6.0 9.0 4.7 43.9 11.4 4.9 23.3 1.2 6.7 9.0 1.9 2.3 25.1 15.9 7.4 196.6 14.8 4.7 17.1 18.2 7.3 4.1 18.6 41.2 3.9 18.3 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 2.5 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 4.5 0.1 0.0 0.1 1.1 0.1 0.1 0.0 2.8 0.0 0.1 0.1 0.8 0.5 0.0 0.0 114.2 0.0 0.1 0.1 0.1 0.1 0.2 0.2 3.0 0.0 3.1 0.0 8.3 188.0 2.5 0.8 747.4 1.1 22.3 0.6 0.5 120.9 19.7 0.8 0.4 9.3 0.8 1486.0 3.2 0.9 137.8 6.3 5.0 4.5 13.7 4.2 8.7 12.8 10.4 11.4 7.4 17.1 18.3 5.0 12.8 31.4 0.0 30.6 2.7 0.8 0.0 0.6 3.6 14.7 9.9 2.1 0.0 3.7 9.2 0.0 1.0 1.4 0.3 0.0 0.0 2.4 0.1 0.0 12.2 0.0 10.1 0.1 0.2 1.7 3.9 1.5 0.1 13.9 0.1 11.0 4.7 311.4 0.0 0.2 0.0 0.0 1060.3 93.4 1.2 1.2 567.5 1.8 59.0 184.8 0.4 4.1 0.0 0.3 0.1 1.1 0.0 1.8 1.1 0.0 0.7 7.3 0.5 19.7 2.2 1.2 0.0 0.4 0.9 1.8 1.9 5.3 0.3 0.1 1.0 RNASE2 "EDN, RAF3, RNS2" ENSG00000169385 "Ribonuclease A family member 2" P10153 14 20955487-20956436 "Enzymes, Plasma proteins, Predicted secreted proteins" Chemotaxis "Endonuclease, Hydrolase, Lyase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 49 "bone marrow: 1713.7" "Cell type enhanced" "Detected in some" "Erythroid cells: 30.7;Kupffer cells: 174.3;Macrophages: 82.2;monocytes: 54.6" "Cancer enriched" "Detected in many" 7 "glioma: 14.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 457.5;eosinophil: 1352.6" "Lineage enriched" "Detected in many" 7 "granulocytes: 1352.6" "Group enriched" "Detected in some" 303 "HL-60: 539.0;NB-4: 539.8;THP-1: 1405.4;U-937: 1295.9" HPA044983 Enhanced "Secreted to blood" NA NA 200000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA044983: AB_10963689" "unprognostic (6.66e-2)" "unprognostic (3.00e-1)" "unprognostic (6.85e-2)" "unprognostic (7.68e-2)" "unprognostic (2.73e-2)" "unprognostic (9.26e-2)" "unprognostic (4.94e-3)" "unprognostic (6.77e-2)" "unprognostic (9.54e-2)" "unprognostic (3.24e-2)" "unprognostic (3.25e-2)" "unprognostic (3.45e-1)" "prognostic unfavorable (3.28e-13)" "unprognostic (2.27e-2)" "unprognostic (7.14e-3)" "unprognostic (5.33e-2)" "unprognostic (1.50e-1)" 7.1 6.0 3.0 9.1 2.8 1713.7 1.7 2.9 5.5 2.3 4.4 2.2 0.2 2.1 0.3 0.9 5.7 2.6 4.0 2.8 4.2 1.7 4.6 12.2 1.9 5.4 4.1 1.5 1.7 0.5 1.7 1.8 4.4 1.7 0.7 1.7 1.9 0.2 0.7 2.9 1.4 9.7 4.5 35.1 2.1 0.7 4.2 14.8 0.9 0.6 0.6 5.2 1.4 6.3 1.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 3.1 0.0 539.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 539.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.3 0.0 0.0 1405.4 0.0 0.0 0.1 0.0 1.2 0.0 0.2 0.7 0.0 1295.9 0.0 457.5 109.0 1352.6 0.4 19.3 0.8 0.3 0.4 0.0 191.8 0.4 0.4 0.4 9.8 0.1 2.8 2.6 0.1 39.9 3.0 2.8 2.9 5.5 2.8 4.2 5.4 4.1 4.4 4.5 4.2 6.3 0.2 3.2 0.5 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.1 1.4 0.0 1.9 0.0 0.5 0.0 0.0 1.3 0.0 30.7 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 1.4 2.2 13.0 0.0 0.0 0.0 0.0 174.3 0.7 1.7 0.3 82.2 0.0 0.0 54.6 0.1 2.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 19.7 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.5 0.0 0.0 0.0 SCIMP "C17orf87, DTFT5783, FLJ32580, MGC163426, MGC163428, UNQ5783" ENSG00000161929 "SLP adaptor and CSK interacting membrane protein" Q6UWF3 17 5208920-5234860 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 49.2" "Cell type enhanced" "Detected in many" "B-cells: 66.4;Hofbauer cells: 26.2;Kupffer cells: 120.3;Macrophages: 66.3;monocytes: 60.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in some" "cerebellum: 2.7" "Group enriched" "Detected in many" 8 "classical monocyte: 110.6;intermediate monocyte: 239.0;memory B-cell: 145.8;myeloid DC: 84.2;naive B-cell: 124.5;non-classical monocyte: 265.5" "Group enriched" "Detected in all" 9 "B-cells: 145.8;dendritic cells: 84.2;monocytes: 265.5" "Cell line enhanced" "Detected in many" "HeLa: 6.8;U-698: 10.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA006117 Enhanced NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA006117: AB_1858633" "unprognostic (2.53e-2)" "unprognostic (7.88e-3)" "unprognostic (1.26e-2)" "unprognostic (5.79e-3)" "unprognostic (1.10e-1)" "unprognostic (3.87e-2)" "unprognostic (7.96e-2)" "unprognostic (1.73e-2)" "unprognostic (4.93e-2)" "unprognostic (2.99e-1)" "unprognostic (1.35e-1)" "unprognostic (8.05e-2)" "unprognostic (3.33e-2)" "unprognostic (2.07e-1)" "unprognostic (4.42e-2)" "unprognostic (1.77e-1)" "unprognostic (9.95e-2)" 5.9 4.1 0.0 30.4 0.1 5.1 1.4 2.7 1.3 1.5 3.6 4.5 5.4 2.9 1.1 1.9 3.1 7.3 1.7 0.3 0.0 2.3 10.6 16.2 39.4 0.6 0.1 3.6 3.9 0.8 0.7 3.9 0.1 3.1 4.6 7.5 4.0 1.4 4.3 3.2 10.2 6.1 0.0 49.2 5.0 2.8 0.0 5.1 3.4 0.8 44.9 6.0 0.6 0.4 1.0 1.5 2.5 3.3 0.0 0.0 2.5 1.1 0.0 0.0 0.0 0.7 2.1 4.8 0.9 0.0 1.8 1.0 0.0 0.0 0.0 0.8 2.1 2.0 6.8 0.7 0.0 0.2 0.7 0.0 0.1 0.0 0.2 1.2 0.0 4.2 0.1 1.2 0.0 1.6 2.4 0.7 1.1 0.3 1.4 2.2 0.5 0.5 0.0 0.6 1.8 0.8 1.8 0.6 1.3 0.7 2.6 2.4 0.3 0.3 1.1 1.4 0.6 0.7 0.3 10.8 1.2 0.3 0.7 16.8 110.6 3.0 1.3 239.0 1.5 145.8 0.8 1.2 84.2 124.5 1.7 1.2 19.0 5.3 265.5 3.2 1.4 68.0 0.0 0.1 2.7 1.3 0.3 0.0 0.6 0.1 0.1 0.0 0.0 0.4 0.5 0.0 4.4 2.6 66.4 0.4 0.4 0.0 0.0 2.5 0.4 0.5 0.4 1.5 0.6 0.0 12.5 0.3 1.5 0.0 0.0 0.7 1.4 0.4 0.3 2.0 0.0 0.4 6.5 0.9 0.3 0.6 0.0 0.1 1.3 0.4 3.3 1.9 26.2 1.7 4.9 0.0 0.0 120.3 4.2 0.7 0.3 66.3 0.0 8.4 60.3 0.4 10.3 4.0 2.3 0.4 0.0 0.4 1.7 0.3 0.0 1.0 1.6 4.1 0.0 0.7 0.3 0.5 0.8 0.0 0.4 0.1 3.2 0.2 0.0 0.4 SIGLEC14 ENSG00000254415 "Sialic acid binding Ig like lectin 14" Q08ET2 19 51642553-51646801 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 28.3;lymphoid tissue: 40.3" "Cell type enhanced" "Detected in some" "Hofbauer cells: 18.5;Kupffer cells: 41.5;Macrophages: 13.5;monocytes: 24.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 109.1;intermediate monocyte: 125.1;myeloid DC: 65.4;neutrophil: 200.1;non-classical monocyte: 93.3" "Group enriched" "Detected in many" 7 "dendritic cells: 65.4;granulocytes: 200.1;monocytes: 125.1" "Group enriched" "Detected in some" 11 "HMC-1: 98.7;U-937: 24.7" "HPA014377, HPA014428" Uncertain Uncertain "Vesicles,Plasma membrane" NA NA 24000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "Plasma membrane" "HPA014377: AB_2189277, HPA014428: " "unprognostic (3.05e-1)" "unprognostic (1.75e-1)" "unprognostic (6.47e-3)" "unprognostic (1.60e-1)" "unprognostic (3.83e-2)" "unprognostic (1.50e-2)" "unprognostic (1.44e-1)" "unprognostic (1.46e-1)" "unprognostic (9.77e-3)" "unprognostic (9.28e-2)" "unprognostic (6.73e-2)" "unprognostic (1.02e-1)" "unprognostic (4.28e-3)" "unprognostic (8.38e-2)" "unprognostic (4.17e-2)" "unprognostic (1.34e-1)" "unprognostic (1.89e-1)" 3.4 2.4 1.4 25.2 1.5 28.3 1.0 1.6 3.2 1.8 1.3 1.8 0.7 0.9 0.3 1.1 2.3 2.6 1.3 1.4 2.4 0.7 3.5 7.3 13.3 4.7 3.0 0.4 1.1 0.4 0.5 2.5 3.9 0.9 1.6 0.1 1.1 0.9 0.4 0.3 6.1 2.5 2.7 40.3 1.6 2.4 3.9 1.9 0.6 0.0 14.2 4.1 0.6 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 1.6 98.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 24.7 0.0 16.6 109.1 1.8 0.3 125.1 0.1 19.3 0.2 0.3 65.4 18.2 0.1 0.1 200.1 0.7 93.3 12.0 0.2 40.3 1.4 1.5 1.6 3.2 1.4 2.4 4.7 3.0 3.9 2.7 3.9 4.1 0.0 0.0 1.1 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 6.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.4 18.5 0.0 0.0 0.0 0.0 41.5 6.0 0.8 0.3 13.5 0.0 1.0 24.1 0.0 2.1 0.0 0.0 0.0 0.0 2.6 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.0 SIGLEC7 "CD328, p75/AIRM1, QA79, SIGLEC-7, SIGLEC19P, SIGLECP2" ENSG00000168995 "Sialic acid binding Ig like lectin 7" Q9Y286 19 51142299-51153526 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 19.2" "Cell type enhanced" "Detected in some" "Hofbauer cells: 31.3;Kupffer cells: 57.4;Macrophages: 33.1;monocytes: 15.5;NK-cells: 69.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 242.1" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 9 "Karpas-707: 55.4;RPMI-8226: 33.7;U-937: 35.0" HPA075513 Approved "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 2600000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" Vesicles "HPA075513: " "unprognostic (3.14e-1)" "unprognostic (5.87e-2)" "unprognostic (1.03e-1)" "unprognostic (2.66e-1)" "unprognostic (3.90e-2)" "unprognostic (1.85e-1)" "unprognostic (2.53e-1)" "unprognostic (2.78e-1)" "unprognostic (1.69e-1)" "unprognostic (4.95e-2)" "unprognostic (1.10e-1)" "unprognostic (2.66e-1)" "unprognostic (8.27e-2)" "unprognostic (6.61e-2)" "unprognostic (1.14e-3)" "unprognostic (2.58e-1)" "unprognostic (2.26e-2)" 3.7 2.9 0.9 10.6 1.0 4.6 1.0 1.0 1.9 0.6 1.2 1.9 1.6 0.5 0.4 0.4 1.2 2.6 1.3 0.8 1.3 1.6 7.4 5.0 7.7 2.1 1.5 0.4 0.5 0.7 0.6 6.2 1.9 0.7 2.4 0.2 0.7 0.4 0.2 0.2 2.2 3.8 1.4 19.2 0.9 0.9 2.2 1.5 0.5 0.3 2.4 3.1 0.5 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.4 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.1 33.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.1 0.0 1.2 1.1 0.0 0.2 35.0 0.0 3.2 140.2 242.1 10.6 105.8 18.9 3.8 0.2 4.8 65.5 0.2 0.3 4.4 116.7 96.8 44.0 2.9 0.0 80.9 0.9 1.0 1.0 1.9 0.8 1.3 2.1 1.5 1.9 1.4 2.2 2.4 0.4 0.0 2.2 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 1.8 0.0 0.2 8.3 0.1 0.0 0.0 0.4 0.0 0.2 0.6 0.0 8.8 0.0 0.0 0.2 0.3 0.0 0.0 1.3 0.0 6.1 0.8 31.3 0.0 0.0 0.0 0.0 57.4 3.5 0.0 1.5 33.1 0.0 0.0 15.5 0.0 69.0 0.0 0.0 0.1 0.0 1.2 0.1 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 3.5 0.4 0.0 0.0 SIGLEC9 CD329 ENSG00000129450 "Sialic acid binding Ig like lectin 9" Q9Y336 19 51124906-51136651 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 20.7" "Cell type enhanced" "Detected in some" "Hofbauer cells: 42.1;Kupffer cells: 39.8;Langerhans cells: 13.4;Macrophages: 26.8;monocytes: 10.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "classical monocyte: 198.9;intermediate monocyte: 182.5;myeloid DC: 169.1;neutrophil: 212.0;non-classical monocyte: 121.9" "Group enriched" "Detected in many" 13 "dendritic cells: 169.1;granulocytes: 212.0;monocytes: 198.9" "Group enriched" "Detected in some" 10 "Karpas-707: 23.4;RPMI-8226: 16.5" HPA010682 Uncertain NA NA 270000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" "HPA010682: AB_1079968" "unprognostic (2.31e-1)" "unprognostic (3.99e-2)" "unprognostic (1.03e-2)" "unprognostic (1.36e-1)" "unprognostic (4.69e-2)" "unprognostic (6.86e-2)" "unprognostic (5.10e-2)" "unprognostic (2.10e-1)" "unprognostic (1.31e-1)" "unprognostic (4.73e-2)" "unprognostic (1.06e-1)" "unprognostic (7.03e-3)" "prognostic unfavorable (6.17e-5)" "unprognostic (6.56e-2)" "unprognostic (7.38e-3)" "unprognostic (2.95e-1)" "unprognostic (1.73e-1)" 8.0 5.4 2.0 17.9 2.1 9.0 1.9 2.2 4.3 1.4 2.8 2.1 1.7 0.9 0.2 0.9 2.5 5.0 2.1 1.9 3.4 1.4 5.5 8.3 5.0 5.4 4.0 3.2 1.2 4.1 0.9 7.9 5.0 1.1 2.4 0.3 1.5 0.9 0.4 0.5 2.2 6.4 4.0 20.7 1.4 1.7 6.2 1.4 0.9 1.3 2.5 5.4 0.8 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 23.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 16.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.3 0.0 0.0 1.5 0.0 0.0 0.0 0.0 2.0 1.5 0.0 17.3 198.9 1.6 15.2 182.5 8.6 0.2 2.5 5.8 169.1 0.1 0.6 2.7 212.0 3.1 121.9 9.2 0.9 84.9 2.0 2.1 2.2 4.3 1.9 3.4 5.4 4.0 5.0 4.0 6.2 5.9 0.1 0.0 0.5 0.0 0.9 0.5 0.0 0.0 0.0 0.0 0.0 0.1 1.7 0.0 1.3 0.0 0.0 0.2 2.7 0.0 0.0 0.0 1.8 0.0 0.1 1.1 0.0 0.0 0.2 0.0 0.4 0.5 0.0 0.0 0.0 0.1 5.3 0.8 42.1 0.0 0.2 0.0 0.0 39.8 13.4 0.4 5.0 26.8 0.0 5.6 10.4 0.0 7.2 0.0 0.1 0.0 0.0 2.2 0.4 0.0 0.0 0.1 0.0 0.0 6.6 0.0 0.1 0.0 0.1 0.0 0.1 0.3 1.3 2.8 0.0 0.0 SLC7A7 "LPI, y+LAT-1" ENSG00000155465 "Solute carrier family 7 member 7" Q9UM01 14 22773222-22829820 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 131.6;kidney: 300.6" "Group enriched" "Detected in many" 4 "Hofbauer cells: 216.5;Kupffer cells: 410.6;Macrophages: 146.2;monocytes: 164.0;Proximal enterocytes: 423.1;Proximal tubular cells: 327.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 299.9;intermediate monocyte: 410.0;non-classical monocyte: 457.1" "Lineage enriched" "Detected in many" 5 "monocytes: 457.1" "Group enriched" "Detected in many" 4 "BEWO: 217.2;CACO-2: 385.7;OE19: 329.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA036227 Enhanced NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA036227: AB_10696653" "unprognostic (1.34e-1)" "unprognostic (7.65e-2)" "unprognostic (4.25e-2)" "unprognostic (2.52e-1)" "unprognostic (6.12e-2)" "unprognostic (3.69e-2)" "unprognostic (7.84e-3)" "unprognostic (1.47e-1)" "unprognostic (2.88e-2)" "unprognostic (1.73e-2)" "unprognostic (2.60e-3)" "unprognostic (7.15e-2)" "prognostic unfavorable (6.28e-6)" "unprognostic (2.68e-3)" "unprognostic (1.86e-2)" "unprognostic (2.61e-1)" "unprognostic (1.12e-1)" 15.1 9.0 3.1 37.4 3.2 19.7 6.8 3.8 7.5 7.3 4.3 13.8 107.0 5.3 2.0 3.7 7.8 17.0 5.1 2.8 3.8 300.6 16.4 54.1 29.1 6.9 4.7 2.1 5.2 78.4 1.4 18.2 6.4 3.5 15.0 1.0 5.4 2.8 2.0 3.2 131.6 15.6 5.1 56.8 8.6 32.8 7.1 9.6 4.6 2.8 25.2 14.7 4.1 8.1 0.2 11.2 1.2 0.5 1.9 3.7 217.2 2.2 16.3 0.4 1.4 385.7 34.4 17.0 72.2 1.4 1.2 13.3 0.1 0.0 0.6 0.6 0.2 0.9 0.4 3.7 9.1 1.9 1.6 7.1 1.0 1.0 0.5 1.8 25.3 1.5 0.1 12.8 2.9 0.6 0.4 1.7 3.6 329.0 0.1 2.9 35.5 9.8 0.8 1.3 0.4 0.8 0.6 0.5 2.5 9.4 0.4 8.3 1.3 0.8 1.7 0.6 0.5 2.7 0.9 8.9 0.9 0.8 0.2 0.2 299.9 1.1 0.5 410.0 0.4 19.1 0.2 0.2 99.5 13.8 0.7 0.4 36.5 0.3 457.1 3.4 0.9 155.1 3.1 3.2 3.8 7.5 2.8 3.8 6.9 4.7 6.4 5.1 7.1 8.1 5.3 12.8 7.1 2.0 14.3 1.0 0.2 6.7 1.8 0.2 0.5 1.7 0.9 67.2 5.6 3.7 0.0 1.2 5.7 3.0 11.7 8.2 61.1 1.7 1.2 5.0 1.2 0.0 0.6 6.4 5.2 4.4 2.6 0.4 1.3 0.7 16.1 3.0 216.5 0.0 1.4 7.2 2.0 410.6 16.8 11.8 3.7 146.2 5.4 20.6 164.0 0.4 4.1 0.0 0.8 8.9 12.5 0.0 20.1 0.1 423.1 327.6 9.2 1.3 6.6 0.8 1.4 17.8 2.2 0.4 0.4 1.8 2.7 38.8 6.4 0.1 SPI1 "OF, PU.1, SFPI1, SPI-1, SPI-A" ENSG00000066336 "Spi-1 proto-oncogene" P17947 11 47354860-47378547 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, RNA-binding" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "bone marrow: 335.1;lung: 101.0;lymphoid tissue: 172.7" "Group enriched" "Detected in many" 6 "Hofbauer cells: 432.9;Kupffer cells: 411.9;Langerhans cells: 537.6;Macrophages: 453.3;monocytes: 357.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 179.7" "Lineage enriched" "Detected in many" 5 "granulocytes: 179.7" "Cell line enhanced" "Detected in some" "HEL: 90.1;HL-60: 159.7;HMC-1: 282.2;NB-4: 267.8;THP-1: 206.7;U-698: 85.3;U-937: 117.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004079, HPA044653" Enhanced Supported Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm "CAB004079: AB_10692379, HPA044653: AB_2679036" "unprognostic (4.45e-2)" "unprognostic (3.31e-3)" "unprognostic (2.92e-2)" "unprognostic (1.66e-2)" "unprognostic (5.97e-2)" "unprognostic (3.33e-2)" "unprognostic (5.28e-2)" "unprognostic (1.07e-1)" "unprognostic (2.35e-2)" "unprognostic (2.79e-1)" "unprognostic (3.36e-1)" "unprognostic (1.78e-1)" "prognostic unfavorable (2.07e-5)" "unprognostic (1.20e-1)" "unprognostic (4.95e-2)" "unprognostic (2.40e-1)" "unprognostic (4.92e-2)" 36.5 19.7 12.0 107.3 13.1 335.1 17.7 14.3 19.4 7.9 15.8 15.6 21.5 7.3 2.1 9.1 19.1 21.3 13.5 11.7 16.4 10.6 15.6 101.0 65.0 31.2 20.9 5.2 7.8 3.1 7.6 28.0 24.7 10.3 10.2 1.0 14.6 6.1 5.0 13.8 29.3 21.9 19.8 172.7 17.0 3.7 26.2 15.7 8.8 8.3 32.0 29.9 7.6 30.3 0.2 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.0 0.2 0.1 0.0 0.0 72.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 90.1 0.0 0.0 0.0 159.7 282.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 11.7 0.7 0.0 0.0 0.2 267.8 0.2 0.0 0.0 48.7 0.2 47.5 0.0 0.0 0.2 0.3 0.0 0.0 0.6 0.0 0.0 206.7 0.3 0.0 0.5 0.5 0.1 0.1 0.3 85.3 0.3 117.5 0.1 14.1 19.2 179.7 0.0 27.4 0.0 3.9 0.0 0.0 16.4 2.4 0.0 0.0 83.8 0.0 34.7 0.9 0.0 7.3 12.0 13.1 14.3 19.4 11.7 16.4 31.2 20.9 24.7 19.8 26.2 30.3 2.1 3.2 1.1 10.4 72.6 10.5 0.5 0.0 1.2 1.3 2.1 5.0 2.9 4.3 0.6 5.5 0.0 2.3 6.3 0.5 19.6 0.1 7.5 0.1 0.3 5.5 4.2 39.7 3.1 0.4 3.1 2.6 1.1 0.3 33.7 0.2 7.9 3.2 432.9 0.0 3.3 0.3 0.0 411.9 537.6 27.5 1.8 453.3 10.6 36.5 357.5 7.0 8.2 3.5 1.5 0.0 0.1 0.0 21.8 0.4 0.2 2.3 0.7 1.7 13.1 1.5 1.4 5.1 9.3 0.8 9.9 4.2 4.8 1.1 0.4 0.5 STAC3 MGC2793 ENSG00000185482 "SH3 and cysteine rich domain 3" Q96MF2 12 57243453-57251188 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 40 "skeletal muscle: 2315.3;tongue: 1169.0" "Cell type enriched" "Detected in many" 7 "Skeletal myocytes: 287.7" "Cancer enhanced" "Detected in all" "head and neck cancer: 11.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 5.8" "Group enriched" "Detected in many" 6 "dendritic cells: 3.6;monocytes: 5.8" "Cell line enriched" "Detected in many" 23 "RH-30: 2282.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA039285, HPA039527" Enhanced Nucleoplasm,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 37: Myocytes - Muscle contraction" Nucleoplasm Cytosol "HPA039285: AB_2676427, HPA039527: AB_10673424" "unprognostic (6.16e-2)" "prognostic favorable (2.01e-4)" "prognostic unfavorable (7.10e-4)" "unprognostic (1.05e-2)" "unprognostic (1.31e-1)" "unprognostic (5.25e-2)" "unprognostic (1.62e-1)" "unprognostic (1.19e-1)" "unprognostic (2.05e-2)" "unprognostic (1.31e-1)" "unprognostic (9.12e-2)" "unprognostic (1.73e-1)" "prognostic unfavorable (7.11e-6)" "unprognostic (4.58e-2)" "unprognostic (3.36e-1)" "unprognostic (2.09e-1)" "unprognostic (1.14e-3)" 2.7 2.0 2.7 7.3 2.5 17.8 2.1 4.6 5.3 1.4 2.3 2.6 2.0 0.8 2.8 31.2 1.7 2.3 1.5 2.6 2.3 1.8 4.4 6.5 8.9 2.7 2.6 1.0 1.4 2.6 2.1 2.9 2.7 23.0 3.0 3.2 43.9 1.1 2315.3 3.4 2.6 2.5 2.1 9.1 1.7 11.9 2.6 4.1 2.1 1169.0 7.4 2.4 1.3 3.1 0.6 0.8 2.1 4.0 1.3 2.2 0.8 0.5 0.5 0.5 0.7 0.5 1.9 55.0 1.1 1.2 0.0 1.0 0.9 1.1 0.2 1.4 1.0 27.9 0.3 0.6 0.5 17.2 97.1 10.0 1.6 0.4 0.6 1.3 0.9 6.1 2.9 2.2 7.5 5.4 1.6 36.3 0.1 0.8 1.0 13.0 2282.0 2.6 1.3 1.2 1.4 1.1 1.6 1.5 0.3 0.3 0.9 48.4 1.0 0.5 0.4 1.6 0.4 2.2 1.2 9.6 1.1 32.9 0.7 0.0 4.4 0.3 0.0 5.8 0.0 0.7 0.0 0.2 3.6 0.3 0.0 0.1 0.2 0.0 2.9 1.0 0.2 1.4 2.7 2.5 4.6 5.3 2.6 2.3 2.7 2.6 2.7 2.1 2.6 3.1 0.4 0.0 0.6 1.3 1.9 1.5 0.4 1.1 0.6 7.5 1.2 1.4 0.3 1.5 0.4 0.0 2.1 1.0 2.8 0.9 0.0 0.8 13.5 1.1 0.6 0.7 2.4 0.4 3.0 1.0 0.7 0.8 1.1 0.9 5.7 1.5 1.8 1.3 39.9 1.7 2.4 1.2 4.1 37.3 16.3 8.9 1.2 24.1 0.0 0.0 26.3 1.5 0.0 1.5 1.2 0.9 1.0 0.7 0.5 1.0 1.6 0.7 2.3 2.5 0.0 287.7 1.0 3.4 1.4 0.6 0.3 1.4 1.6 0.8 1.2 0.4 TMEM150B "DRAM3, TMEM224, TTN2" ENSG00000180061 "Transmembrane protein 150B" A6NC51 19 55312801-55334048 "Predicted membrane proteins, Transporters" Autophagy "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 5 "intestine: 64.1" "Cell type enhanced" "Detected in some" "Distal enterocytes: 18.1;Kupffer cells: 11.8;monocytes: 8.0;Proximal enterocytes: 68.9" "Cancer enhanced" "Detected in many" "colorectal cancer: 11.6" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "classical monocyte: 5.7" "Group enriched" "Detected in many" 7 "granulocytes: 1.9;monocytes: 5.7" "Cell line enhanced" "Detected in some" "CACO-2: 8.3;HMC-1: 3.8;THP-1: 2.9;U-937: 18.1" "Not detected" "Not detected" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 56: Intestine - Transmembrane transport" "Cluster 32: U-937 - Innate immune response" "Cluster 45: Enterocytes - Digestion" "unprognostic (3.19e-2)" "unprognostic (1.00e-1)" "unprognostic (5.76e-2)" "unprognostic (4.94e-2)" "unprognostic (5.33e-2)" "unprognostic (6.70e-2)" "unprognostic (5.51e-2)" "unprognostic (1.35e-1)" "unprognostic (5.35e-2)" "unprognostic (4.00e-2)" "unprognostic (4.74e-2)" "unprognostic (3.06e-1)" "prognostic unfavorable (6.14e-6)" "unprognostic (1.48e-1)" "unprognostic (1.63e-3)" "unprognostic (2.45e-1)" "unprognostic (1.18e-2)" 3.7 1.8 0.5 5.8 0.8 0.7 1.1 0.4 1.0 0.3 1.2 10.2 64.1 0.4 0.1 0.6 0.8 2.9 0.8 0.4 0.7 3.2 2.2 11.9 3.5 1.3 0.7 0.3 0.9 0.1 0.2 5.6 1.6 0.3 7.3 0.0 0.6 0.4 0.2 0.2 57.0 4.1 0.5 5.7 1.4 0.5 3.4 0.7 0.3 0.2 1.6 2.0 0.3 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 8.3 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 1.6 0.0 1.1 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 1.9 0.0 0.0 0.1 0.1 0.1 1.8 0.0 0.2 0.0 2.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 2.9 0.1 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 18.1 0.1 1.9 5.7 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.8 0.5 0.8 0.4 1.0 0.4 0.7 1.3 0.7 1.6 0.5 3.4 1.3 0.0 0.0 0.0 0.0 0.6 0.1 1.3 0.0 0.0 0.0 0.1 0.0 0.5 1.5 0.0 1.8 0.0 0.0 0.0 18.1 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.4 0.8 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.1 6.7 0.0 0.7 3.5 0.0 11.8 1.3 0.0 0.0 3.2 0.0 0.0 8.0 0.0 0.0 0.0 0.9 0.3 1.4 0.0 0.9 0.6 68.9 0.6 0.0 0.0 0.0 0.2 0.2 0.1 0.1 0.0 0.0 0.0 0.2 0.0 3.7 0.3 VSIG4 "CRIg, Z39IG" ENSG00000155659 "V-set and immunoglobulin domain containing 4" Q9Y279 X 66021738-66040125 "Plasma proteins, Predicted membrane proteins" "Complement alternate pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 166.0" "Group enriched" "Detected in many" 5 "Hofbauer cells: 989.8;Kupffer cells: 590.9;Macrophages: 328.4" "Cancer enriched" "Detected in all" 5 "glioma: 88.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 27 "classical monocyte: 18.7;intermediate monocyte: 11.1;myeloid DC: 17.8" "Group enriched" "Detected in many" 31 "dendritic cells: 17.8;monocytes: 18.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA003903, CAB026000" Enhanced Uncertain "Nucleoli,Plasma membrane,Cytosol" NA NA 59000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 19: Lung - Lung function" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane, Cytosol" Nucleoli "CAB026000: , HPA003903: AB_1858776" "unprognostic (6.87e-3)" "unprognostic (4.79e-2)" "prognostic unfavorable (1.34e-4)" "unprognostic (3.19e-1)" "unprognostic (1.30e-2)" "unprognostic (1.53e-2)" "unprognostic (9.37e-3)" "unprognostic (1.24e-1)" "unprognostic (3.10e-1)" "unprognostic (1.37e-3)" "unprognostic (1.06e-1)" "unprognostic (2.77e-1)" "prognostic unfavorable (1.95e-6)" "unprognostic (3.70e-2)" "unprognostic (5.45e-2)" "unprognostic (3.37e-2)" "unprognostic (3.47e-2)" 137.1 68.8 17.9 44.2 18.8 7.8 44.2 17.0 36.6 14.1 21.5 40.9 22.5 15.5 5.3 15.4 66.8 39.6 30.0 18.2 18.3 17.9 51.0 166.0 27.8 25.1 23.6 12.9 14.3 6.8 7.0 139.6 25.8 10.6 31.7 2.2 24.5 9.3 8.2 10.8 43.9 108.3 18.9 69.3 22.9 7.3 37.6 5.4 12.3 12.5 1.8 61.5 11.6 26.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 18.7 0.1 0.0 11.1 0.0 0.0 0.0 0.2 17.8 0.1 0.0 0.0 0.5 0.0 0.4 0.1 0.0 5.6 17.9 18.8 17.0 36.6 18.2 18.3 25.1 23.6 25.8 18.9 37.6 26.7 1.3 3.2 16.1 0.0 1.2 2.3 0.3 0.0 0.0 0.0 2.6 0.5 1.8 7.2 3.1 0.0 0.0 5.3 0.3 0.0 0.0 0.1 7.9 0.0 0.0 10.4 0.0 0.0 0.0 0.0 4.9 2.7 0.0 0.0 3.8 0.0 5.0 3.2 989.8 0.0 0.0 0.0 0.0 590.9 111.8 16.6 1.5 328.4 3.6 12.2 1.5 0.5 0.0 0.5 0.0 0.0 0.1 0.4 0.3 0.3 0.0 0.1 4.4 0.0 6.6 0.6 2.0 0.3 0.9 0.5 1.7 12.3 1.5 0.0 0.0 0.2 WDFY4 "C10orf64, Em:AC060234.3, FLJ45748, KIAA1607" ENSG00000128815 "WDFY family member 4" Q6ZS81 10 48684876-48982956 "Predicted intracellular proteins, Predicted membrane proteins" Autophagy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 11.7;lymphoid tissue: 28.5" "Cell type enhanced" "Detected in some" "B-cells: 44.7;dendritic cells: 29.9;Early spermatids: 47.2;Langerhans cells: 30.6;Macrophages: 24.6;Microglial cells: 81.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "memory B-cell: 14.3;myeloid DC: 11.3;naive B-cell: 21.2;neutrophil: 10.2;plasmacytoid DC: 32.5" "Group enriched" "Detected in many" 7 "B-cells: 21.2;dendritic cells: 32.5;granulocytes: 10.2" "Cell line enhanced" "Detected in some" "Daudi: 61.0;HDLM-2: 56.3;HL-60: 21.5;THP-1: 18.9;U-698: 25.6;U-937: 25.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA040634 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm Cytosol "HPA040634: AB_10795491" "unprognostic (6.20e-2)" "unprognostic (6.60e-3)" "unprognostic (1.87e-1)" "unprognostic (3.31e-2)" "unprognostic (1.87e-1)" "unprognostic (9.38e-4)" "unprognostic (9.41e-2)" "unprognostic (3.89e-3)" "unprognostic (2.15e-2)" "unprognostic (3.74e-1)" "unprognostic (3.49e-2)" "unprognostic (9.64e-2)" "unprognostic (3.21e-1)" "unprognostic (1.34e-1)" "unprognostic (1.35e-2)" "unprognostic (1.97e-1)" "unprognostic (3.76e-2)" 1.9 0.7 3.2 12.1 3.4 11.7 1.4 4.2 4.8 1.1 3.2 1.9 1.5 0.8 1.9 1.4 0.7 3.2 0.6 3.2 4.2 0.8 1.3 5.2 28.5 6.0 4.9 0.6 1.0 0.4 0.3 1.2 6.2 0.8 1.9 0.1 1.3 0.6 0.7 2.6 7.4 1.7 5.9 17.3 2.3 3.7 6.3 12.3 0.6 0.4 23.9 3.1 0.3 9.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 61.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 56.3 0.0 6.5 0.0 0.0 0.0 21.5 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.1 0.0 0.0 0.0 0.0 11.9 0.0 0.0 0.0 6.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 25.6 0.0 25.0 0.0 0.0 3.0 0.0 0.0 2.8 0.0 14.3 0.0 0.1 11.3 21.2 0.0 0.0 10.2 0.0 1.3 32.5 0.0 1.1 3.2 3.4 4.2 4.8 3.2 4.2 6.0 4.9 6.2 5.9 6.3 9.3 0.2 0.0 1.1 2.0 44.7 0.4 0.1 0.0 0.0 0.0 0.1 0.4 1.3 0.0 0.6 1.8 0.0 0.1 29.9 0.0 1.9 0.0 47.2 0.0 0.1 0.3 0.0 0.4 0.7 0.0 0.2 1.1 0.0 0.0 5.7 0.0 0.0 0.0 13.0 0.0 0.4 0.1 0.0 12.9 30.6 17.7 0.3 24.6 1.8 81.5 16.4 0.0 0.0 1.0 0.5 0.0 0.0 0.4 3.3 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.2 2.9 0.5 0.2 0.3 0.3 1.5 0.0 0.3 0.1