Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" ACTR3 ARP3 ENSG00000115091 "Actin related protein 3" P61158 2 113890063-113962596 "Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005085, HPA047016, HPA051683" Approved NA NA 25000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 10: Non-specific - Unknown function" "CAB005085: AB_2289106, HPA047016: AB_2679903, HPA051683: AB_2681573" "unprognostic (7.28e-2)" "prognostic unfavorable (6.52e-5)" "unprognostic (2.03e-2)" "unprognostic (1.01e-3)" "unprognostic (1.14e-1)" "unprognostic (1.05e-2)" "prognostic unfavorable (7.76e-5)" "unprognostic (9.27e-3)" "unprognostic (1.63e-1)" "unprognostic (2.50e-2)" "unprognostic (2.74e-2)" "unprognostic (1.56e-1)" "prognostic unfavorable (3.81e-5)" "unprognostic (2.57e-1)" "unprognostic (2.54e-2)" "unprognostic (3.44e-2)" "unprognostic (4.44e-1)" 97.5 125.3 29.9 229.7 36.4 216.5 64.5 37.6 41.0 62.7 52.4 129.3 107.4 78.1 47.2 167.1 58.1 84.4 71.7 48.0 41.9 79.4 89.9 97.9 291.2 46.4 38.2 46.4 64.3 54.7 23.1 101.4 41.7 71.3 125.1 31.7 64.3 83.6 47.8 77.7 119.0 137.0 36.2 155.8 113.1 84.8 39.0 185.8 67.3 49.8 331.3 153.6 67.1 46.7 377.8 179.1 249.4 170.6 178.0 251.7 259.9 518.7 395.0 369.7 349.1 379.9 233.6 538.7 590.6 487.9 497.1 200.0 262.3 286.5 486.7 806.2 135.6 502.7 210.2 296.2 314.8 474.0 879.1 227.1 220.8 484.9 316.5 216.1 348.6 207.1 273.9 393.8 493.1 153.2 429.7 204.5 187.2 254.8 297.5 328.8 246.8 273.4 381.0 348.9 124.0 124.1 263.0 269.7 330.6 188.7 112.7 387.7 514.6 440.9 288.3 205.6 451.5 208.5 446.5 635.4 385.5 304.2 417.7 753.0 478.9 1048.4 464.4 728.1 381.6 455.9 424.6 460.6 634.4 385.0 371.4 437.9 777.1 479.9 887.7 191.4 587.0 1265.4 29.9 36.4 37.6 41.0 48.0 41.9 46.4 38.2 41.7 36.2 39.0 46.7 113.7 89.8 64.1 26.4 254.0 331.9 369.7 139.1 93.9 32.0 57.5 48.9 68.5 57.2 125.4 68.0 8.4 144.6 196.5 164.4 129.1 220.8 113.6 109.2 100.8 138.9 85.3 154.8 40.1 154.8 316.6 101.4 122.9 171.0 267.5 88.4 81.0 72.9 339.2 38.7 40.4 120.2 105.8 201.4 413.7 108.3 45.4 288.1 112.1 69.3 316.5 46.7 286.3 58.3 67.6 177.0 168.1 73.0 158.7 181.7 103.3 132.4 117.7 19.5 65.7 58.5 194.1 207.1 74.7 173.4 353.8 205.6 264.4 242.2 120.3 314.1 ANKRD31 FLJ40191 ENSG00000145700 "Ankyrin repeat domain 31" Q8N7Z5 5 75068275-75236911 "Predicted intracellular proteins" "DNA recombination, Meiosis" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "testis: 4.9" "Group enriched" "Detected in some" 7 "Spermatocytes: 148.9;Spermatogonia: 37.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA038028, HPA057566" Enhanced Approved Nucleoplasm,Nucleoli,Vesicles,Centrosome NA NA "Cluster 35: T-regs - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoplasm, Centrosome" "Nucleoli, Vesicles" "HPA038028: AB_10672615, HPA057566: AB_2683470" "unprognostic (1.37e-1)" "unprognostic (4.28e-2)" "unprognostic (5.25e-2)" "unprognostic (5.57e-2)" "unprognostic (1.65e-1)" "unprognostic (5.72e-2)" "unprognostic (4.81e-2)" "unprognostic (2.52e-2)" "unprognostic (3.63e-1)" "unprognostic (1.83e-1)" "unprognostic (1.02e-2)" "unprognostic (1.69e-1)" "unprognostic (3.00e-2)" "unprognostic (4.46e-2)" "unprognostic (5.48e-2)" "unprognostic (1.24e-2)" "unprognostic (1.40e-1)" 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.1 0.1 0.3 0.0 0.0 0.1 0.1 0.1 0.7 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.2 0.3 0.2 0.1 0.2 0.1 0.0 0.2 0.1 0.0 0.3 0.2 0.1 0.0 0.1 0.1 0.0 0.2 0.0 0.0 4.9 0.1 0.2 0.0 0.0 0.0 0.0 0.4 0.3 0.2 0.1 0.1 0.9 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.1 0.0 0.3 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.2 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.3 0.2 0.2 0.1 0.3 0.1 0.0 0.5 5.2 0.4 0.4 0.4 0.5 0.6 3.3 0.8 1.1 1.1 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.3 3.6 2.8 0.8 0.1 0.0 0.8 5.8 0.2 0.6 0.4 4.1 0.4 12.0 0.5 0.4 0.0 0.1 1.7 5.4 0.0 0.0 0.0 0.0 4.7 1.5 0.1 0.0 1.0 0.1 1.3 0.0 3.0 5.6 0.1 0.1 0.4 1.3 0.0 0.1 0.3 1.2 2.2 13.1 0.6 0.4 148.9 37.7 0.4 0.1 0.3 1.1 0.7 0.1 0.2 ANKRD62 DKFZp779B1634 ENSG00000181626 "Ankyrin repeat domain 62" A6NC57 18 12093843-12129764 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 6 "brain: 1.1;pancreas: 1.0;testis: 1.6" "Cell type enriched" "Detected in some" 5 "Spermatocytes: 92.8" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA059835 Enhanced Uncertain "Nucleoplasm,Nuclear bodies,Actin filaments" NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Nuclear bodies" "Actin filaments" "HPA059835: AB_2684136" "unprognostic (2.45e-2)" "unprognostic (1.18e-1)" "unprognostic (2.37e-3)" "unprognostic (9.46e-2)" "unprognostic (3.01e-1)" "unprognostic (1.98e-1)" "unprognostic (6.61e-2)" "unprognostic (7.95e-2)" "unprognostic (3.27e-1)" "unprognostic (2.55e-4)" "unprognostic (1.13e-1)" "unprognostic (3.28e-2)" "unprognostic (4.52e-3)" "unprognostic (8.70e-2)" 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.4 0.0 0.6 0.0 0.7 0.0 0.0 0.4 0.1 0.0 1.3 0.3 0.1 0.4 0.3 0.0 0.0 1.7 0.4 0.1 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 2.2 0.1 0.2 0.5 0.0 0.0 16.5 1.7 0.6 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.6 0.8 2.6 0.6 0.2 0.0 1.0 0.0 0.1 1.0 1.0 0.2 0.5 1.1 0.4 0.0 0.8 0.2 0.0 0.0 0.9 0.0 1.3 0.3 92.8 15.8 0.5 1.1 0.0 0.2 0.1 0.2 0.5 ANLN "ANILLIN, scra, Scraps" ENSG00000011426 "Anillin actin binding protein" Q9NQW6 7 36389821-36453791 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Actin-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 266.0" "Group enriched" "Detected in many" 5 "Early spermatids: 156.4;Oligodendrocytes: 441.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "HBF TERT88: 655.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005680, CAB033902, HPA050556, CAB062547, CAB068175" Enhanced Enhanced Nucleoplasm,Midbody Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 70: Brain - Nervous system development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm Midbody "CAB033902: AB_2058302, CAB062547: AB_2665622, CAB068175: AB_2665623, HPA005680: AB_2667388, HPA050556: AB_2681175" "unprognostic (4.23e-2)" "unprognostic (1.59e-3)" "unprognostic (1.49e-1)" "prognostic unfavorable (1.73e-4)" "unprognostic (1.67e-2)" "unprognostic (3.44e-2)" "prognostic unfavorable (5.97e-7)" "prognostic unfavorable (6.99e-5)" "unprognostic (2.69e-2)" "unprognostic (3.66e-2)" "prognostic unfavorable (2.00e-6)" "unprognostic (3.13e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (5.29e-2)" "unprognostic (1.34e-1)" "unprognostic (2.94e-2)" "unprognostic (4.04e-3)" 1.2 0.7 59.8 5.2 134.5 36.4 2.0 125.1 72.7 1.8 18.4 6.0 4.4 1.8 0.2 10.4 0.9 2.1 0.8 59.3 83.6 0.4 1.2 1.4 6.7 162.3 106.5 0.9 0.6 0.2 0.2 8.9 160.2 0.9 8.0 0.3 1.7 0.4 0.3 13.6 4.3 14.9 99.2 1.2 4.8 12.4 102.3 16.0 0.8 0.3 9.5 3.2 3.2 266.0 476.1 96.5 79.3 61.0 10.7 26.9 85.6 292.5 169.3 344.4 256.0 66.4 142.7 23.9 82.1 148.6 182.8 237.0 63.4 170.7 655.4 16.1 46.0 32.7 104.8 55.8 1.7 47.3 36.7 6.0 7.7 225.3 147.2 40.8 109.3 31.2 69.6 48.8 284.4 71.0 40.0 54.8 88.5 71.9 102.3 29.1 238.2 15.9 76.5 76.5 33.5 39.5 154.1 175.8 26.1 109.6 119.0 53.6 104.5 214.2 239.0 127.6 346.6 20.1 34.2 43.2 72.9 74.9 460.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.3 59.8 134.5 125.1 72.7 59.3 83.6 162.3 106.5 160.2 99.2 102.3 266.0 0.4 0.0 1.1 2.3 1.0 14.1 1.9 8.3 7.4 0.0 1.9 2.0 0.6 0.0 3.2 0.0 0.0 13.8 1.1 2.8 0.0 0.7 156.4 18.9 3.2 1.9 0.0 35.3 3.4 0.2 23.2 6.9 10.2 12.8 0.0 15.4 1.1 0.5 9.8 0.0 5.7 3.4 6.1 1.6 5.9 53.3 1.2 2.7 0.0 0.0 0.0 0.0 0.0 1.5 441.3 0.6 0.1 0.0 8.8 1.6 0.8 0.3 10.4 0.0 0.0 0.4 5.2 20.0 17.7 27.1 9.2 2.9 2.6 1.7 6.0 3.3 ARFGAP3 ARFGAP1 ENSG00000242247 "ADP ribosylation factor GTPase activating protein 3" Q9NP61 22 42796502-42858106 "Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000638 Approved Supported "Golgi apparatus,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "Golgi apparatus" "HPA000638: AB_1078188" "unprognostic (3.29e-2)" "unprognostic (6.08e-2)" "unprognostic (3.22e-1)" "prognostic favorable (8.97e-6)" "unprognostic (5.83e-2)" "unprognostic (8.85e-3)" "unprognostic (5.00e-3)" "unprognostic (1.00e-1)" "unprognostic (2.05e-1)" "unprognostic (1.31e-1)" "unprognostic (9.06e-3)" "unprognostic (1.67e-1)" "unprognostic (1.87e-1)" "unprognostic (2.52e-2)" "unprognostic (2.08e-1)" "prognostic unfavorable (2.65e-4)" "unprognostic (1.73e-1)" 30.1 88.9 16.5 34.1 17.4 47.8 30.9 19.5 20.4 56.1 23.2 26.9 36.5 32.2 53.3 22.1 22.9 36.6 23.6 17.9 20.6 53.2 49.2 32.3 28.1 20.5 18.7 20.7 85.8 38.0 38.1 34.8 20.3 64.7 30.6 35.5 68.5 40.2 31.3 20.7 51.1 30.8 19.0 26.0 43.2 49.5 19.6 25.9 61.3 21.8 32.6 45.2 23.4 21.0 59.6 19.3 41.1 24.7 57.2 94.1 17.3 111.8 76.4 50.5 60.9 23.5 32.8 30.1 24.5 102.9 41.8 14.4 18.7 33.0 54.7 18.5 25.4 35.7 27.6 37.4 79.6 31.9 53.2 42.0 57.6 42.6 75.9 71.9 52.4 27.4 16.1 132.0 89.6 15.7 49.4 17.5 6.7 32.7 23.2 31.1 92.3 38.3 80.7 27.5 14.6 9.0 54.3 21.5 46.0 30.6 22.7 24.4 67.0 58.7 42.5 52.1 30.7 94.7 48.2 33.1 41.9 34.0 46.7 86.2 33.2 36.8 45.1 44.4 58.8 27.1 29.7 39.8 32.5 26.1 19.2 27.2 50.8 49.4 50.9 53.1 28.8 30.1 16.5 17.4 19.5 20.4 17.9 20.6 20.5 18.7 20.3 19.0 19.6 21.0 40.8 38.5 54.8 27.4 41.7 26.6 86.9 43.0 19.9 42.8 43.1 29.5 26.5 37.1 62.1 57.0 18.8 18.8 67.3 36.4 66.5 65.9 19.1 60.5 89.9 42.4 49.1 17.5 26.1 64.3 23.7 58.1 30.1 96.3 65.9 28.4 30.4 37.3 28.7 33.7 28.8 53.0 46.8 21.7 89.3 15.0 48.1 68.2 69.4 35.6 33.7 40.5 38.1 43.7 40.0 83.0 15.6 45.5 110.0 121.5 70.9 62.9 65.5 33.7 39.5 80.0 65.5 178.7 67.6 14.6 26.7 59.9 49.6 39.0 22.7 86.7 ARHGAP11A KIAA0013 ENSG00000198826 "Rho GTPase activating protein 11A" Q6P4F7 15 32615144-32639941 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 24.2;lymphoid tissue: 26.1" "Cell type enhanced" "Detected in many" "Erythroid cells: 38.7;Extravillous trophoblasts: 23.7;Granulosa cells: 21.1;Plasma cells: 18.6;Spermatocytes: 24.7;Spermatogonia: 22.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040830, HPA066481" Enhanced Approved Nucleoli,Cytosol No Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol Nucleoli "HPA040830: AB_10805830, HPA066481: " "unprognostic (5.00e-2)" "unprognostic (5.57e-2)" "unprognostic (6.10e-2)" "unprognostic (1.97e-1)" "unprognostic (2.93e-1)" "unprognostic (3.41e-2)" "prognostic unfavorable (2.05e-4)" "prognostic unfavorable (8.69e-4)" "unprognostic (4.87e-2)" "unprognostic (7.71e-2)" "prognostic unfavorable (2.92e-5)" "unprognostic (3.43e-2)" "unprognostic (1.07e-12)" "unprognostic (7.37e-2)" "unprognostic (5.23e-1)" "unprognostic (1.54e-2)" "unprognostic (9.64e-2)" 1.7 0.9 2.0 7.9 2.5 24.2 1.7 2.1 2.1 1.5 1.2 7.5 6.1 1.5 1.0 5.3 0.8 1.7 0.7 1.7 1.9 0.6 1.3 1.7 13.5 2.6 3.0 0.6 2.6 1.2 0.7 4.3 2.6 0.6 8.8 0.5 1.2 0.5 0.9 4.4 7.6 4.8 2.5 2.8 3.6 8.6 2.2 26.1 1.3 0.4 14.3 2.8 1.9 3.0 80.8 69.4 73.1 46.2 5.0 13.0 39.6 78.5 50.2 80.0 63.3 52.2 41.5 43.5 23.7 49.9 91.3 56.9 55.3 43.8 110.9 83.5 27.4 132.6 68.9 33.5 2.0 103.8 55.5 4.3 5.5 61.6 50.9 15.2 61.5 94.4 101.0 112.7 95.3 31.7 58.6 39.7 44.6 71.6 44.5 67.8 141.7 38.2 28.4 41.6 64.7 44.5 72.9 46.2 17.6 37.6 63.6 115.8 35.3 102.5 74.1 42.0 87.2 38.3 63.7 123.7 44.4 129.1 91.8 0.1 0.3 0.8 0.5 0.5 0.2 0.3 1.0 0.9 0.4 0.2 0.4 0.5 0.0 0.1 0.1 0.2 0.8 0.3 2.0 2.5 2.1 2.1 1.7 1.9 2.6 3.0 2.6 2.5 2.2 3.0 0.7 0.0 2.3 0.3 4.6 4.8 1.1 2.4 2.2 0.2 1.3 1.7 0.9 4.3 1.9 1.8 0.0 9.8 2.9 6.2 0.0 0.8 4.7 3.8 2.6 2.0 0.0 38.7 1.0 0.8 23.7 3.5 8.6 2.8 0.0 21.1 1.8 2.1 9.5 0.0 0.6 7.8 0.0 6.5 4.2 5.0 0.6 3.5 0.0 1.0 3.9 0.1 2.1 0.5 1.4 0.5 2.9 0.4 18.6 1.4 1.1 0.4 1.4 1.0 6.6 1.4 3.3 24.7 22.6 10.5 2.3 3.1 5.4 2.0 14.1 2.1 ARIH2 TRIAD1 ENSG00000177479 "Ariadne RBR E3 ubiquitin protein ligase 2" O95376 3 48918821-48986382 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA067381, HPA069715, HPA070963" Enhanced Nucleoplasm NA NA "Cluster 44: Non-specific - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "HPA067381: AB_2685827, HPA069715: AB_2686182, HPA070963: AB_2686329" "unprognostic (7.24e-2)" "unprognostic (1.08e-1)" "unprognostic (1.26e-1)" "unprognostic (2.74e-1)" "unprognostic (2.55e-1)" "unprognostic (4.79e-3)" "prognostic unfavorable (1.70e-4)" "unprognostic (1.90e-2)" "unprognostic (4.01e-2)" "unprognostic (5.01e-2)" "prognostic favorable (7.31e-4)" "unprognostic (5.01e-3)" "prognostic favorable (6.60e-4)" "unprognostic (1.15e-1)" "unprognostic (7.04e-2)" "unprognostic (1.27e-2)" "unprognostic (1.39e-2)" 20.6 22.9 21.4 16.0 24.5 23.0 19.8 24.2 23.7 21.4 24.7 29.4 11.7 24.5 33.8 19.5 21.3 15.0 53.9 21.3 23.4 22.7 21.3 19.7 20.7 22.9 22.9 20.7 24.1 24.4 26.0 18.4 23.8 23.1 17.7 32.4 18.6 21.9 100.4 16.5 21.2 24.4 22.0 24.3 22.5 27.0 22.8 26.1 22.0 79.6 21.4 23.6 17.4 27.7 40.4 39.6 37.6 53.2 54.3 29.7 52.4 46.3 53.5 56.5 62.1 42.0 35.0 84.1 21.4 49.8 82.0 23.5 77.9 47.2 68.7 57.0 48.1 85.3 51.7 34.5 48.9 63.4 39.5 31.9 70.2 70.9 94.9 32.2 43.1 38.3 68.4 54.6 50.7 27.8 65.4 25.8 64.3 43.3 59.5 23.5 42.8 70.2 32.9 54.1 16.4 44.8 47.7 56.1 45.0 44.1 28.6 43.8 41.4 34.1 49.4 52.5 74.0 72.8 148.1 103.3 37.3 51.9 43.7 53.1 34.6 39.9 44.2 32.2 30.5 28.8 28.2 37.1 32.3 34.2 29.2 37.3 25.6 25.8 20.9 29.9 35.5 39.3 21.4 24.5 24.2 23.7 21.3 23.4 22.9 22.9 23.8 22.0 22.8 27.7 37.0 35.3 31.4 54.9 50.2 50.9 51.5 27.3 68.3 57.0 35.5 35.3 74.6 32.9 44.0 29.5 87.6 36.4 76.0 31.3 29.4 33.8 15.3 33.5 48.3 38.4 16.7 76.2 50.0 43.2 36.2 40.1 42.3 38.1 45.5 42.3 28.5 44.6 26.6 57.2 59.1 26.2 14.2 32.8 35.7 11.3 41.7 44.6 30.2 38.4 45.2 42.2 95.8 42.3 128.6 42.1 23.0 43.2 85.0 78.9 20.8 34.3 30.6 82.5 26.3 51.5 48.6 165.7 89.7 59.4 54.0 53.4 66.8 37.7 31.6 67.0 ASF1B FLJ10604 ENSG00000105011 "Anti-silencing function 1B histone chaperone" Q9NVP2 19 14119512-14136613 "Predicted intracellular proteins" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Chaperone, Chromatin regulator, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 23.2;testis: 32.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 36.1;Early spermatids: 36.4;Erythroid cells: 43.6;Extravillous trophoblasts: 35.4;Spermatocytes: 73.2;Spermatogonia: 87.8" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 7 "neutrophil: 60.1" "Lineage enriched" "Detected in all" 7 "granulocytes: 60.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA054036, HPA069385" Enhanced Supported Nucleoplasm NA Yes "Cluster 9: Neutrophils - Innate immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA054036: AB_2682350, HPA069385: " "unprognostic (3.14e-1)" "prognostic favorable (4.45e-5)" "unprognostic (2.41e-3)" "unprognostic (2.40e-1)" "unprognostic (2.15e-1)" "unprognostic (2.27e-2)" "prognostic unfavorable (2.03e-4)" "unprognostic (2.87e-2)" "unprognostic (1.33e-3)" "unprognostic (1.52e-1)" "prognostic unfavorable (1.98e-4)" "unprognostic (8.48e-3)" "prognostic unfavorable (2.22e-16)" "prognostic favorable (2.49e-4)" "unprognostic (1.27e-1)" "unprognostic (3.92e-2)" "unprognostic (4.31e-2)" 0.9 1.4 0.2 5.6 0.3 11.7 1.3 0.3 0.2 2.2 0.1 7.4 5.3 1.0 0.1 10.3 0.7 0.7 0.7 0.1 0.2 1.0 1.3 2.1 12.5 0.3 0.2 0.7 0.7 0.3 0.7 3.6 0.3 0.8 7.7 0.0 1.9 0.3 0.5 3.2 6.0 2.0 0.2 6.7 3.2 32.0 0.3 23.2 0.6 0.4 14.7 1.8 3.2 0.3 64.6 25.3 37.7 28.9 3.8 3.6 16.2 33.1 28.3 63.8 79.5 26.5 31.6 59.1 30.0 17.5 26.5 38.0 41.8 24.1 49.7 54.0 26.9 55.5 48.7 18.6 0.2 39.0 35.1 0.7 1.7 35.8 12.4 7.2 25.1 44.1 50.2 83.8 31.8 75.7 80.8 34.3 17.3 69.1 56.7 77.0 56.0 51.6 20.1 28.3 46.0 16.5 39.8 29.2 17.4 10.3 22.1 41.5 10.6 36.0 21.6 91.0 56.6 43.2 46.5 80.3 28.0 71.9 36.1 0.7 6.2 1.5 1.7 8.0 0.9 1.1 1.5 2.0 1.2 0.9 0.9 1.7 60.1 1.7 8.5 0.5 5.1 3.2 0.2 0.3 0.3 0.2 0.1 0.2 0.3 0.2 0.3 0.2 0.3 0.3 1.0 0.0 0.6 0.3 5.6 2.5 2.4 4.5 1.2 0.1 4.8 8.5 1.2 1.5 1.1 0.0 0.0 36.1 3.8 11.7 0.0 1.0 36.4 2.1 1.3 2.1 1.2 43.6 0.5 1.2 35.4 4.1 23.4 2.3 4.5 9.2 0.4 0.3 21.5 0.0 0.4 9.9 8.2 5.6 5.6 29.1 0.0 5.0 1.8 1.0 2.1 0.3 4.1 0.0 0.5 1.1 2.2 0.7 20.1 1.0 2.4 0.3 0.2 0.9 0.0 1.1 3.3 73.2 87.8 8.3 1.1 10.4 5.3 3.0 20.9 2.4 ASPM "ASP, Calmbp1, FLJ10517, FLJ10549, MCPH5" ENSG00000066279 "Assembly factor for spindle microtubules" Q8IZT6 1 197084121-197146694 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Calmodulin-binding "Cancer-related genes, Disease variant, Mental retardation, Primary microcephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 10.1;lymphoid tissue: 17.0" "Cell type enhanced" "Detected in many" "Erythroid cells: 99.5;Granulosa cells: 121.1;Plasma cells: 44.8;Spermatocytes: 43.8;Spermatogonia: 44.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" CAB017816 Approved "Plasma membrane,Cytosol" NA Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Cytosol" "CAB017816: " "unprognostic (3.24e-1)" "unprognostic (1.56e-1)" "unprognostic (2.81e-2)" "prognostic unfavorable (1.97e-4)" "unprognostic (3.67e-1)" "unprognostic (3.47e-2)" "prognostic unfavorable (1.25e-4)" "prognostic unfavorable (2.41e-4)" "unprognostic (4.67e-3)" "unprognostic (9.29e-2)" "prognostic unfavorable (2.40e-4)" "unprognostic (1.03e-1)" "unprognostic (0.00e+0)" "unprognostic (7.31e-3)" "unprognostic (1.23e-1)" "unprognostic (4.94e-2)" "unprognostic (3.66e-2)" 0.2 0.1 0.0 3.0 0.0 10.1 0.4 0.0 0.1 0.2 0.0 1.6 2.1 0.3 0.0 1.5 0.0 0.3 0.1 0.0 0.0 0.0 0.6 0.3 5.3 0.0 0.0 0.1 0.0 0.0 0.0 1.5 0.0 0.1 1.9 0.0 0.2 0.0 0.0 2.7 1.9 0.7 0.0 0.9 1.1 3.2 0.1 17.0 0.1 0.0 5.1 0.6 0.4 0.2 44.6 22.9 39.1 23.2 1.9 5.5 14.7 35.1 23.2 32.6 25.6 16.7 31.1 45.4 12.5 27.5 13.8 40.2 33.6 12.1 39.1 41.8 25.4 33.1 56.1 12.8 0.4 51.9 20.5 0.6 1.0 26.1 15.2 7.3 31.5 32.9 41.8 50.7 29.0 16.0 40.6 10.3 17.8 24.8 6.4 30.2 55.5 31.7 7.4 11.4 20.4 29.5 50.6 20.6 9.5 20.8 26.9 12.7 28.9 20.9 20.0 34.9 61.2 13.9 21.6 26.8 14.9 11.0 42.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.6 0.0 1.1 1.3 5.8 6.1 1.5 4.0 2.2 0.1 2.4 2.4 1.1 0.0 1.3 1.8 0.0 20.0 7.8 7.7 0.0 0.3 3.9 2.9 6.2 4.3 0.0 99.5 2.0 0.0 14.8 9.8 13.3 8.1 1.3 121.1 6.4 2.2 11.6 0.0 4.8 6.8 4.1 6.4 2.4 4.5 0.6 6.4 0.0 0.0 0.9 0.7 4.1 0.0 1.0 0.5 0.2 1.5 44.8 2.0 0.4 0.4 0.8 0.3 0.0 0.6 7.0 43.8 44.7 27.1 3.4 3.7 9.1 5.7 16.9 2.1 ASZ1 "ALP1, ANKL1, C7orf7, CT1.19, GASZ, Orf3" ENSG00000154438 "Ankyrin repeat, SAM and basic leucine zipper domain containing 1" Q8WWH4 7 117363222-117428123 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Meiosis, RNA-mediated gene silencing, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 15 "testis: 10.7" "Group enriched" "Detected in some" 8 "Spermatocytes: 89.0;Spermatogonia: 23.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA020558 Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Cytosol Nucleoplasm "HPA020558: AB_1845123" "unprognostic (4.30e-1)" "unprognostic (1.87e-1)" "unprognostic (1.42e-1)" 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 10.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.3 0.1 0.2 0.3 0.1 0.2 0.1 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.4 0.0 0.2 0.0 0.1 0.0 0.0 6.6 0.2 0.0 89.0 23.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 ATAD2 "ANCCA, CT137, DKFZp667N1320, MGC29843, MGC5254, PRO2000" ENSG00000156802 "ATPase family AAA domain containing 2" Q6PL18 8 123319850-123416350 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 28.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 79.1;Spermatocytes: 106.0;Spermatogonia: 82.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 294.4" "Low region specificity" "Detected in all" "HPA029424, CAB056158" Enhanced Enhanced Nucleoplasm Yes Yes "Cluster 33: Neutrophils - Chromatin organization" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB056158: AB_2665580, HPA029424: AB_10611680" "unprognostic (1.56e-1)" "unprognostic (4.55e-2)" "unprognostic (2.07e-1)" "prognostic unfavorable (2.04e-4)" "unprognostic (2.08e-1)" "unprognostic (4.44e-2)" "unprognostic (2.98e-2)" "unprognostic (2.74e-3)" "unprognostic (2.02e-3)" "unprognostic (5.62e-2)" "unprognostic (1.19e-2)" "unprognostic (4.98e-2)" "prognostic unfavorable (8.33e-15)" "unprognostic (1.15e-2)" "unprognostic (1.82e-1)" "unprognostic (4.84e-2)" "unprognostic (6.17e-2)" 2.9 3.4 3.8 7.7 3.6 26.5 6.8 2.6 3.9 12.8 2.0 5.3 5.0 4.3 3.8 6.8 3.4 3.2 5.8 3.2 4.5 1.4 9.9 4.1 14.4 2.9 3.8 7.0 3.3 1.9 3.9 4.8 2.6 10.3 6.9 1.4 4.3 4.7 9.3 6.8 5.2 4.1 2.8 4.9 4.7 18.9 5.1 28.3 3.9 3.2 12.8 4.8 3.9 2.8 103.7 39.6 55.0 19.0 9.7 12.3 24.3 79.2 27.2 66.8 73.9 30.1 43.8 67.2 23.6 25.2 26.5 48.3 74.2 25.6 106.1 94.3 39.0 121.2 41.0 61.4 3.8 44.6 57.4 4.1 3.8 63.6 21.0 14.3 20.7 38.6 57.7 66.4 50.4 107.1 129.5 32.8 10.0 77.8 38.4 66.5 65.6 36.4 23.8 46.7 70.2 30.5 114.4 294.4 20.8 22.1 60.2 41.2 13.0 50.4 69.3 40.2 96.6 21.2 40.7 60.8 32.9 72.9 40.4 5.3 0.8 3.3 1.6 0.8 2.2 2.6 2.3 2.7 1.4 1.5 1.5 1.7 0.2 2.5 1.9 0.1 4.6 1.0 3.8 3.6 2.6 3.9 3.2 4.5 2.9 3.8 2.6 2.8 5.1 2.8 4.8 6.4 11.0 9.4 18.5 15.8 27.9 9.1 14.2 2.8 17.3 21.2 27.3 2.8 10.2 3.7 4.2 14.9 15.3 9.0 1.9 3.5 54.9 7.9 17.3 9.6 1.2 79.1 25.6 2.2 26.2 17.1 13.3 17.5 14.5 37.9 7.1 16.3 11.2 1.7 16.4 13.1 4.1 8.2 6.9 24.4 7.5 11.7 1.8 14.0 6.3 6.3 17.5 11.6 2.8 3.5 4.3 13.9 34.0 20.7 3.1 1.0 5.4 1.9 0.0 9.5 17.5 106.0 82.4 23.7 12.1 13.5 22.8 3.7 14.6 24.5 ATP6V1B2 "ATP6B2, HO57, VATB, Vma2, VPP3" ENSG00000147416 "ATPase H+ transporting V1 subunit B2" P21281 8 20197381-20226819 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" Hydrolase "Deafness, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 256.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1130.7" "Group enriched" "Detected in all" 10 "dendritic cells: 336.8;granulocytes: 1130.7;monocytes: 682.0" "Cell line enhanced" "Detected in all" "SK-MEL-30: 317.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008147 Enhanced Supported Vesicles NA NA 310000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 58: Brain - Synaptic function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA008147: AB_1845195" "unprognostic (1.90e-1)" "unprognostic (7.24e-3)" "unprognostic (3.62e-2)" "unprognostic (2.57e-1)" "unprognostic (2.84e-2)" "unprognostic (5.59e-3)" "unprognostic (1.76e-2)" "unprognostic (3.78e-2)" "unprognostic (4.68e-2)" "unprognostic (4.23e-3)" "unprognostic (1.29e-2)" "unprognostic (1.34e-1)" "prognostic favorable (8.41e-4)" "unprognostic (2.41e-1)" "unprognostic (2.09e-2)" "unprognostic (2.47e-2)" "unprognostic (5.25e-2)" 46.4 76.4 112.6 71.9 111.2 45.7 35.3 72.8 126.0 30.1 72.5 38.0 43.9 29.4 31.0 51.3 32.8 39.0 38.2 124.0 135.5 145.8 49.2 72.7 54.1 103.4 120.0 27.5 34.5 71.4 74.5 50.5 138.2 28.1 43.0 205.7 40.4 27.0 66.7 62.5 57.8 40.1 74.8 66.1 32.8 67.8 100.3 50.2 33.4 64.7 48.9 44.5 36.1 99.5 44.2 71.5 87.4 29.2 117.7 72.3 79.1 96.6 61.5 121.5 125.2 81.7 25.4 77.7 38.4 93.1 123.7 36.8 70.1 64.6 129.0 32.9 47.2 54.2 29.9 63.6 137.6 39.0 108.0 65.0 57.9 76.0 69.3 134.1 77.2 101.2 82.0 72.8 132.5 25.0 114.6 46.2 65.6 64.6 31.5 46.6 113.4 40.8 112.9 68.2 68.0 97.9 46.9 62.7 317.9 72.4 81.6 70.7 82.8 61.1 46.3 101.9 78.5 29.4 42.7 90.9 84.6 91.6 158.4 183.7 682.0 485.9 52.9 618.6 57.7 50.2 54.1 56.8 336.8 44.5 54.4 53.7 1130.7 50.8 576.1 82.7 73.0 622.6 112.6 111.2 72.8 126.0 124.0 135.5 103.4 120.0 138.2 74.8 100.3 99.5 16.6 25.6 20.7 20.5 28.1 58.0 28.4 52.1 33.0 106.1 18.5 15.6 17.6 25.8 28.8 29.5 102.2 109.2 38.9 23.3 80.3 43.2 40.8 20.2 13.6 24.1 74.4 35.8 64.3 38.5 56.4 38.8 25.0 35.9 22.2 22.3 25.7 34.7 178.5 190.1 68.0 21.4 36.7 185.2 178.7 24.4 19.6 167.6 104.9 30.0 169.1 51.5 20.6 27.6 29.0 45.2 19.7 28.2 20.7 17.4 75.0 256.7 18.0 137.8 13.1 29.3 34.2 121.6 55.3 43.3 71.6 124.6 27.1 23.1 24.7 20.1 ATR "FRP1, MEC1, SCKL, SCKL1" ENSG00000175054 "ATR serine/threonine kinase" Q13535 3 142449007-142578733 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "DNA damage, DNA repair" "DNA-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 93.0;Inhibitory neurons: 94.4;Microglial cells: 73.1;Oligodendrocyte precursor cells: 65.4;Oligodendrocytes: 71.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054320 Supported "Nucleoplasm,Golgi apparatus" No No "Cluster 15: NK-cells - Transcription" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Golgi apparatus" "HPA054320: AB_2682448" "unprognostic (1.47e-1)" "unprognostic (8.90e-2)" "unprognostic (2.90e-1)" "unprognostic (4.23e-2)" "unprognostic (2.25e-2)" "unprognostic (6.42e-2)" "prognostic unfavorable (8.39e-5)" "unprognostic (3.44e-1)" "unprognostic (1.67e-1)" "unprognostic (3.02e-1)" "prognostic unfavorable (1.23e-5)" "unprognostic (1.94e-1)" "unprognostic (5.61e-2)" "unprognostic (1.06e-1)" "unprognostic (3.55e-1)" "unprognostic (1.69e-2)" "unprognostic (1.43e-1)" 3.0 8.6 0.7 4.1 1.1 1.2 3.2 0.9 1.4 3.8 3.7 2.7 1.7 3.3 2.3 3.1 3.3 3.4 2.3 1.2 1.9 3.7 3.6 2.9 4.8 1.5 1.2 2.7 3.8 5.2 3.7 3.1 1.4 3.0 2.9 2.9 3.5 2.5 2.9 2.7 3.1 3.2 1.0 4.2 2.8 5.2 1.2 4.9 5.0 1.4 4.6 4.1 2.7 1.2 28.6 13.2 7.1 7.0 9.6 13.6 8.8 14.8 8.4 10.1 9.7 6.4 6.8 19.9 14.6 10.1 14.6 16.1 10.9 12.8 15.0 7.5 7.9 11.9 8.2 4.1 4.2 20.5 5.3 9.8 4.8 9.5 10.3 5.8 11.6 8.7 8.2 7.5 9.6 7.5 13.9 2.6 7.3 15.6 9.6 11.8 12.5 13.5 6.3 11.1 5.2 5.1 28.6 8.3 8.0 7.8 12.0 5.4 14.6 10.5 4.9 12.3 15.2 10.8 7.4 18.5 13.8 6.5 8.5 0.0 0.3 0.0 0.5 0.4 1.0 0.1 0.3 0.5 0.7 0.3 0.4 0.4 0.0 1.3 0.2 0.2 0.4 0.2 0.7 1.1 0.9 1.4 1.2 1.9 1.5 1.2 1.4 1.0 1.2 1.2 11.5 6.4 10.6 39.2 22.4 4.0 7.2 8.8 14.2 14.1 9.2 6.5 7.6 5.7 10.1 3.7 37.5 7.7 14.9 3.5 0.0 5.9 16.4 18.8 18.6 10.2 7.7 14.5 93.0 4.9 3.6 8.3 14.8 10.3 1.3 16.3 7.9 7.3 6.4 8.4 94.4 4.8 14.2 9.4 4.0 8.7 6.5 12.8 10.6 73.1 12.0 6.0 9.2 65.4 71.9 6.4 1.8 7.2 23.1 8.1 1.9 6.5 25.4 23.6 0.0 14.6 9.8 50.1 18.5 14.7 4.5 5.1 15.1 13.8 7.6 6.1 ATXN1L BOAT1 ENSG00000224470 "Ataxin 1 like" P0C7T5 16 71845976-71885268 "Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Late spermatids: 263.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062596, HPA062789" Enhanced Nucleoplasm NA NA "Cluster 35: T-regs - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "HPA062596: AB_2684802, HPA062789: AB_2684868" "unprognostic (1.51e-1)" "unprognostic (1.73e-2)" "unprognostic (1.39e-1)" "unprognostic (1.67e-1)" "unprognostic (3.01e-2)" "unprognostic (1.01e-1)" "unprognostic (1.68e-1)" "unprognostic (1.14e-1)" "unprognostic (1.00e-1)" "unprognostic (1.04e-1)" "unprognostic (8.13e-2)" "unprognostic (1.99e-1)" "prognostic favorable (5.33e-8)" "unprognostic (1.61e-1)" "unprognostic (1.42e-1)" "unprognostic (5.30e-2)" "prognostic unfavorable (8.42e-4)" 14.0 8.0 11.5 9.9 12.7 39.5 10.9 9.0 9.7 11.1 5.6 10.4 8.2 12.3 7.3 9.7 10.9 9.0 9.5 9.3 9.4 18.7 6.6 12.0 10.0 10.9 11.7 12.7 12.5 16.5 5.2 10.8 10.3 8.1 9.2 8.0 9.4 10.4 10.4 12.1 9.4 12.9 10.3 11.8 10.0 12.2 12.5 12.8 11.9 13.7 10.5 8.9 7.4 11.9 11.8 15.7 15.7 11.5 18.1 8.9 18.4 9.8 10.8 17.4 13.2 22.6 12.9 13.2 15.0 15.4 8.0 20.3 13.4 14.9 18.9 3.6 11.9 9.7 17.7 15.9 13.5 11.9 19.0 12.8 18.6 19.8 14.2 11.4 16.0 17.0 11.1 10.2 10.4 33.6 20.2 11.7 14.3 9.3 7.4 21.4 15.9 15.8 12.1 16.4 8.3 14.2 19.5 10.2 11.9 16.4 16.0 12.5 19.4 19.0 19.9 12.1 13.3 23.0 20.8 30.7 11.8 7.9 16.3 0.6 0.3 0.3 0.4 0.4 0.3 0.3 0.3 0.4 0.2 0.2 0.5 0.5 0.4 0.4 0.2 0.1 0.7 0.3 11.5 12.7 9.0 9.7 9.3 9.4 10.9 11.7 10.3 10.3 12.5 11.9 11.1 0.0 10.6 4.2 14.9 22.8 15.3 11.4 14.2 11.2 16.0 10.2 15.7 14.3 9.5 14.7 14.6 8.3 19.9 15.2 17.6 11.9 44.2 19.1 15.0 14.2 7.8 5.7 6.8 11.8 7.9 11.0 5.6 35.4 12.7 8.0 14.3 12.3 8.5 15.2 5.7 8.7 8.2 14.3 25.2 263.0 14.9 11.8 12.4 5.6 16.9 6.3 29.9 3.5 9.1 14.4 19.6 12.8 16.0 18.3 13.3 15.8 9.9 17.2 13.1 15.5 14.3 22.4 21.1 13.1 24.9 11.5 15.8 8.0 10.6 28.4 BBS7 "BBS2L1, FLJ10715" ENSG00000138686 "Bardet-Biedl syndrome 7" Q8IWZ6 4 121824329-121870487 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Sensory transduction, Transport, Vision" "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Mental retardation, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "retina: 56.6" "Cell type enhanced" "Detected in all" "Excitatory neurons: 65.1;Inhibitory neurons: 58.6;Rod photoreceptor cells: 68.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044592 Approved NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA044592: AB_10795882" "unprognostic (6.36e-2)" "unprognostic (3.11e-3)" "unprognostic (1.37e-2)" "unprognostic (1.85e-1)" "unprognostic (1.10e-2)" "unprognostic (1.89e-1)" "unprognostic (3.15e-5)" "unprognostic (6.66e-3)" "unprognostic (1.44e-1)" "unprognostic (2.48e-1)" "unprognostic (1.49e-1)" "unprognostic (9.10e-3)" "unprognostic (2.67e-2)" "unprognostic (1.62e-1)" "unprognostic (4.22e-2)" "unprognostic (1.41e-1)" "unprognostic (4.33e-1)" 6.9 6.4 7.3 5.3 7.7 2.1 6.1 9.8 12.4 7.9 2.6 6.3 5.0 10.5 4.9 6.2 7.9 5.9 4.7 7.7 6.4 6.7 2.4 5.3 5.0 8.9 7.8 12.4 3.7 9.1 9.1 4.7 8.7 6.8 6.3 56.6 4.8 6.6 3.8 6.8 5.3 10.3 5.1 4.6 4.8 9.1 8.4 6.4 5.5 5.5 4.8 5.8 6.9 8.9 13.7 6.6 14.9 10.9 18.8 27.2 5.4 18.3 14.6 15.5 14.2 5.2 7.4 15.0 5.1 21.7 11.6 7.1 15.5 14.8 17.6 14.4 12.1 8.9 10.0 6.2 16.7 12.7 8.0 14.0 10.6 17.7 13.3 20.2 16.8 10.0 6.0 14.8 22.1 4.3 21.3 6.1 7.9 8.3 8.2 9.7 19.3 4.6 15.7 4.8 16.4 7.0 17.5 7.7 14.0 19.7 6.5 4.7 16.9 11.6 12.5 16.2 11.8 13.9 10.3 13.1 13.4 10.0 11.6 0.6 1.0 1.7 1.9 1.1 1.5 0.9 1.5 1.8 1.2 0.9 1.2 1.6 0.2 2.0 1.2 1.2 1.6 1.0 7.3 7.7 9.8 12.4 7.7 6.4 8.9 7.8 8.7 5.1 8.4 8.9 15.7 6.4 8.4 12.7 6.9 8.7 10.8 13.7 5.7 16.6 6.0 9.3 8.4 4.3 13.0 11.0 47.9 8.5 6.6 6.4 13.7 14.6 22.2 14.4 19.9 11.2 6.1 9.5 65.1 9.8 21.5 14.4 6.1 10.6 15.2 9.2 8.6 5.0 11.4 16.8 58.6 8.2 16.2 6.3 6.1 12.9 13.1 7.7 8.8 16.9 6.3 12.6 5.2 30.7 26.4 15.6 5.1 11.3 5.6 9.3 6.0 15.1 16.5 68.9 19.7 12.2 15.2 39.6 22.4 10.9 8.5 5.7 10.7 11.4 8.4 8.6 BEND2 "CXorf20, MGC33653" ENSG00000177324 "BEN domain containing 2" Q8NDZ0 X 18162931-18220886 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 17 "testis: 5.3" "Cell type enhanced" "Detected in some" "Leydig cells: 18.6;Peritubular cells: 13.2;Spermatocytes: 84.5;Spermatogonia: 29.0" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 4 "basophil: 2.9" "Lineage enriched" "Detected in single" 15 "granulocytes: 2.9" "Not detected" "Not detected" "HPA009420, HPA013142" Enhanced NA NA "Cluster 34: Basophils - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA009420: AB_2064489, HPA013142: AB_2668784" "unprognostic (2.23e-2)" "unprognostic (1.17e-1)" 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.1 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 5.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.7 0.1 0.0 0.1 0.0 1.8 0.1 0.1 0.1 0.3 0.1 0.1 0.1 0.2 0.2 0.0 0.2 0.2 0.0 0.0 1.3 0.0 0.3 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.7 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.2 18.6 5.7 0.0 0.0 0.7 0.0 1.0 0.0 0.1 0.0 0.0 13.2 0.0 0.6 0.0 0.0 0.7 0.0 6.6 0.3 0.2 84.5 29.0 0.0 0.4 0.0 0.1 0.0 0.0 0.4 BLM "BS, RECQ2, RECQL3" ENSG00000197299 "BLM RecQ like helicase" P54132 15 90717346-90816166 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.7;lymphoid tissue: 7.9;salivary gland: 7.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 18.3;Oligodendrocyte precursor cells: 58.3;Plasma cells: 20.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005689 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "HPA005689: AB_1845372" "unprognostic (2.77e-1)" "unprognostic (3.82e-3)" "unprognostic (4.03e-2)" "unprognostic (2.98e-2)" "unprognostic (4.75e-2)" "unprognostic (9.89e-2)" "unprognostic (6.12e-5)" "unprognostic (2.82e-2)" "unprognostic (4.55e-3)" "unprognostic (5.24e-3)" "unprognostic (1.80e-3)" "unprognostic (9.12e-2)" "unprognostic (1.55e-15)" "unprognostic (6.53e-3)" "unprognostic (6.55e-2)" "unprognostic (2.43e-1)" "unprognostic (1.83e-2)" 0.3 0.2 0.9 3.6 1.1 5.7 0.5 2.3 0.9 0.1 0.3 1.4 1.0 0.4 0.4 0.6 0.3 0.3 0.3 0.8 1.1 0.1 0.1 0.4 6.4 1.2 1.4 0.1 0.2 0.0 0.6 1.2 1.1 0.1 1.7 2.4 7.8 0.0 0.5 0.4 1.6 0.4 1.0 1.6 1.1 2.2 0.9 7.9 0.3 0.1 6.2 1.0 0.2 1.0 13.0 14.4 20.4 12.6 0.1 0.9 14.6 9.4 3.2 11.1 13.4 11.7 10.1 35.1 5.9 2.6 14.1 20.4 25.7 7.1 15.1 19.1 20.5 36.4 14.8 3.9 0.0 33.7 17.3 0.3 0.1 10.6 4.7 1.3 7.9 16.9 32.7 9.9 11.0 7.4 28.3 14.5 22.2 24.9 4.2 25.4 39.1 14.7 2.3 18.9 14.6 14.7 8.5 11.5 4.8 18.1 7.2 23.4 3.7 8.6 13.6 9.6 21.0 6.4 30.4 39.5 5.6 25.8 15.7 1.7 0.6 2.6 1.6 0.8 2.6 4.6 1.4 2.1 0.7 2.3 1.0 1.1 0.7 3.1 1.0 0.7 3.2 0.9 0.9 1.1 2.3 0.9 0.8 1.1 1.2 1.4 1.1 1.0 0.9 1.0 0.9 3.2 8.9 1.0 12.9 0.3 0.5 0.5 0.6 3.6 1.3 1.0 7.9 0.0 4.2 0.0 2.1 5.5 6.9 2.2 1.9 1.0 2.7 1.3 1.3 2.0 0.0 18.3 0.7 0.7 6.8 1.8 3.6 1.7 13.3 8.1 2.2 0.6 5.7 0.0 8.6 1.3 0.0 7.7 1.3 1.6 0.0 7.7 0.0 7.5 2.7 1.7 10.3 58.3 2.6 1.2 0.3 0.4 20.6 0.7 0.2 0.0 5.4 7.1 0.0 0.9 1.7 17.1 12.9 2.2 0.6 1.0 10.2 0.7 4.0 0.4 BRCA1 "BRCC1, FANCS, PPP1R53, RNF53" ENSG00000012048 "BRCA1 DNA repair associated" P38398 17 43044295-43170245 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA recombination, DNA repair, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, DNA-binding, Transferase" "Cancer-related genes, Disease variant, Fanconi anemia, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 42.5;Granulosa cells: 38.2;Spermatocytes: 105.8;Spermatogonia: 73.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 6.8;classical monocyte: 14.7;intermediate monocyte: 4.7;myeloid DC: 10.9;neutrophil: 11.3" "Group enriched" "Detected in all" 6 "dendritic cells: 10.9;granulocytes: 11.3;monocytes: 14.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB001946, HPA004840, HPA034966, HPA057371" Approved Supported "Nucleoplasm,Nuclear bodies" NA Yes "Cluster 25: Monocytes - Inflammatory response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nuclear bodies" "CAB001946: , HPA004840: , HPA034966: AB_10795287, HPA057371: AB_2732611" "unprognostic (7.87e-3)" "unprognostic (6.97e-2)" "unprognostic (3.53e-3)" "unprognostic (2.39e-1)" "unprognostic (5.42e-2)" "unprognostic (7.07e-3)" "unprognostic (1.56e-3)" "unprognostic (4.14e-3)" "unprognostic (9.62e-3)" "unprognostic (2.47e-1)" "unprognostic (5.53e-3)" "unprognostic (1.28e-1)" "unprognostic (1.08e-4)" "unprognostic (1.08e-3)" "unprognostic (1.48e-1)" "unprognostic (2.12e-1)" "unprognostic (8.31e-2)" 3.1 1.8 4.2 7.5 7.2 13.0 3.6 4.7 5.2 2.7 2.7 6.8 3.2 3.1 2.2 4.0 3.7 1.9 3.0 3.6 4.1 2.0 5.6 3.2 10.3 5.6 5.0 2.8 2.8 5.9 2.8 3.8 6.0 2.4 7.4 8.2 3.2 1.6 4.2 6.0 5.1 3.9 3.7 3.9 3.6 13.0 5.5 14.5 7.8 3.7 11.2 2.8 2.4 10.8 44.1 69.1 37.8 30.1 6.0 13.4 36.6 50.6 21.5 41.9 39.3 42.3 33.4 100.8 9.1 19.0 49.0 49.5 51.9 28.3 69.5 46.9 38.0 48.1 54.0 37.1 1.3 86.0 39.9 3.8 4.5 63.1 20.0 10.6 22.3 46.6 73.7 42.2 39.7 30.0 72.0 27.8 20.5 29.1 18.7 49.0 79.8 40.8 15.4 42.1 25.8 27.4 38.8 12.5 19.4 25.5 33.9 39.6 13.8 37.2 29.6 49.0 53.2 20.1 51.2 75.5 29.6 49.6 39.4 6.8 14.7 2.2 1.5 4.7 1.5 1.2 1.5 1.2 10.9 2.1 1.3 1.5 11.3 1.5 2.0 1.7 0.5 17.5 4.2 7.2 4.7 5.2 3.6 4.1 5.6 5.0 6.0 3.7 5.5 10.8 5.0 0.0 2.8 9.4 5.8 2.9 4.5 1.9 1.2 10.3 4.4 5.2 10.1 5.7 3.5 1.8 22.9 12.8 8.1 6.2 0.0 3.0 11.9 14.0 6.3 4.7 0.0 42.5 3.0 1.1 18.2 7.4 6.1 4.2 8.2 38.2 5.3 18.3 10.1 11.8 4.4 7.5 0.0 3.9 2.8 8.0 2.5 6.4 0.0 4.7 4.9 2.4 5.2 3.0 18.7 1.7 2.4 1.5 16.6 2.3 1.1 1.0 10.0 22.8 6.6 13.7 5.5 105.8 73.5 8.2 2.3 4.0 4.7 9.7 12.7 3.4 BRCA2 "BRCC2, FACD, FAD, FAD1, FANCD, FANCD1, XRCC11" ENSG00000139618 "BRCA2 DNA repair associated" P51587 13 32315086-32400268 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA recombination, DNA repair" DNA-binding "Cancer-related genes, Disease variant, Fanconi anemia, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.8;lymphoid tissue: 3.1;testis: 2.7" "Cell type enhanced" "Detected in many" "Spermatocytes: 115.4;Spermatogonia: 85.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" HPA026815 Uncertain Supported Nucleoplasm,Cytosol Yes No "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "HPA026815: AB_10602692" "unprognostic (9.36e-2)" "unprognostic (2.50e-1)" "unprognostic (4.50e-3)" "unprognostic (1.06e-2)" "unprognostic (5.40e-2)" "unprognostic (2.26e-2)" "unprognostic (1.37e-2)" "unprognostic (1.15e-1)" "unprognostic (1.60e-2)" "unprognostic (2.01e-1)" "unprognostic (6.97e-3)" "unprognostic (4.06e-2)" "unprognostic (3.07e-9)" "unprognostic (2.36e-2)" "unprognostic (1.18e-1)" "unprognostic (1.88e-1)" "unprognostic (1.32e-1)" 0.2 0.1 0.0 1.3 0.0 5.8 0.5 0.0 0.0 0.2 0.2 0.7 0.5 0.3 0.0 0.5 0.1 0.3 0.0 0.0 0.0 0.1 0.3 0.3 2.1 0.1 0.1 0.1 0.1 0.0 0.0 1.0 0.1 0.1 0.8 0.0 0.2 0.0 0.0 0.7 0.5 0.3 0.1 0.9 0.6 2.7 0.2 3.1 0.2 0.0 2.0 0.5 0.2 0.1 4.7 4.0 6.0 5.0 0.6 1.4 7.0 4.8 3.1 5.5 5.0 10.6 6.0 15.9 3.2 2.1 7.6 6.1 5.5 2.9 10.5 10.5 3.1 10.3 2.5 3.5 0.1 15.4 4.9 0.2 0.0 10.3 6.9 0.4 4.5 8.1 7.0 5.5 6.4 5.1 11.8 8.3 8.3 4.9 2.3 11.4 17.3 3.0 1.4 5.4 2.4 4.6 5.9 2.4 2.2 2.2 2.9 7.3 1.3 6.3 6.8 7.0 6.7 2.0 3.3 8.0 2.7 5.7 5.8 0.0 0.3 1.5 0.5 0.7 0.1 1.7 0.4 0.4 0.3 2.2 0.5 0.4 0.8 0.5 0.8 3.0 1.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.2 0.1 4.4 9.6 2.6 0.0 12.4 2.5 3.3 2.5 2.2 0.0 4.3 3.3 1.9 0.0 1.8 0.0 0.0 14.1 10.5 4.8 0.0 2.5 5.2 4.4 6.3 5.5 1.2 29.5 0.7 1.6 12.7 5.8 10.7 4.6 3.8 26.9 1.4 0.8 9.5 0.0 0.5 4.4 0.0 7.5 11.0 4.4 2.1 14.4 3.6 4.7 20.1 0.3 0.0 0.0 0.6 1.2 1.8 1.2 27.8 1.2 1.0 0.6 2.9 0.0 13.1 8.3 5.3 115.4 85.6 8.0 1.3 5.5 7.9 4.2 7.8 2.3 BUB1 "BUB1A, BUB1L, hBUB1" ENSG00000169679 "BUB1 mitotic checkpoint serine/threonine kinase" O43683 2 110637528-110678063 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Chromosome partition, Host-virus interaction, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 11.9;lymphoid tissue: 27.5;testis: 30.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 24.8;Granulosa cells: 66.1;Plasma cells: 35.2;Spermatocytes: 85.6;Spermatogonia: 20.0" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 221.5" "Region enhanced" "Detected in single" "white matter: 1.7" "Not detected" "Not detected" HPA006123 Supported Nucleoplasm,Cytosol NA Yes "Cluster 46: Basophils - DNA binding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 36: HEL - Hemostasis" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "HPA006123: AB_1845498" "unprognostic (7.74e-2)" "unprognostic (3.45e-2)" "unprognostic (9.72e-3)" "prognostic unfavorable (3.65e-4)" "unprognostic (1.61e-1)" "unprognostic (5.62e-3)" "prognostic unfavorable (1.03e-5)" "prognostic unfavorable (3.94e-4)" "unprognostic (1.26e-3)" "unprognostic (1.15e-1)" "prognostic unfavorable (2.37e-5)" "unprognostic (1.76e-1)" "unprognostic (0.00e+0)" "unprognostic (2.45e-2)" "unprognostic (3.64e-1)" "unprognostic (5.01e-2)" "unprognostic (1.28e-1)" 0.5 0.4 0.1 8.4 0.3 11.9 1.2 0.1 0.1 0.9 0.0 4.3 4.0 1.0 3.5 4.7 0.5 0.9 0.6 0.1 0.1 0.3 0.6 1.2 15.9 0.1 0.6 0.4 0.2 0.7 0.0 3.2 0.3 0.3 5.7 0.1 0.9 0.1 0.1 2.7 3.5 2.2 0.0 5.6 1.9 30.3 0.4 27.5 0.4 0.2 17.0 2.4 1.6 0.3 96.0 29.4 68.5 46.8 3.8 5.3 38.8 50.9 32.9 85.6 62.3 58.3 55.0 64.7 30.9 30.1 80.1 43.2 93.9 35.0 105.7 51.4 45.6 221.5 26.2 50.6 0.8 63.5 57.0 1.7 2.8 65.2 33.1 12.7 49.8 73.2 96.8 126.5 76.8 33.7 126.3 39.0 71.2 39.4 55.3 69.3 64.2 102.7 18.3 27.0 48.3 21.4 34.2 31.4 27.2 44.1 24.0 60.6 19.1 39.7 57.5 28.8 69.0 67.3 65.5 75.4 24.2 48.6 69.8 1.1 0.0 0.2 0.2 0.0 0.3 0.5 0.9 0.5 0.1 0.5 0.6 0.4 0.0 0.5 0.0 0.9 1.5 0.3 0.1 0.3 0.1 0.1 0.1 0.1 0.1 0.6 0.3 0.0 0.4 0.3 0.2 0.0 1.5 0.0 5.5 0.5 0.5 2.0 0.6 0.0 0.9 0.8 1.1 0.0 1.6 0.0 0.0 5.8 2.5 2.4 0.0 0.3 13.5 4.5 1.5 1.1 0.0 24.8 0.2 0.0 9.8 2.2 2.0 2.2 0.0 66.1 1.8 0.3 8.1 0.0 0.2 3.1 4.1 1.6 1.4 7.5 0.3 2.0 0.0 0.0 0.6 0.0 0.0 0.5 1.0 0.1 0.0 0.4 35.2 0.5 0.3 0.1 1.8 0.0 6.6 0.2 3.7 85.6 20.0 4.0 0.4 0.7 2.9 0.5 5.9 0.9 BUB1B "Bub1A, BUBR1, MAD3L, SSK1" ENSG00000156970 "BUB1 mitotic checkpoint serine/threonine kinase B" O60566 15 40161023-40221123 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 17.8;lymphoid tissue: 35.7;testis: 22.2" "Cell type enhanced" "Detected in many" "Erythroid cells: 23.5;Spermatocytes: 79.2;Spermatogonia: 26.8" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.1" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" HPA008419 Supported Cytosol Yes Yes "Cluster 24: B-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA008419: AB_1078308" "unprognostic (4.40e-2)" "unprognostic (2.23e-1)" "unprognostic (4.65e-2)" "unprognostic (2.44e-3)" "unprognostic (9.66e-2)" "unprognostic (3.52e-2)" "prognostic unfavorable (7.43e-6)" "prognostic unfavorable (3.56e-4)" "unprognostic (3.69e-3)" "unprognostic (2.32e-1)" "prognostic unfavorable (1.79e-4)" "unprognostic (1.76e-2)" "unprognostic (0.00e+0)" "unprognostic (3.75e-2)" "unprognostic (4.66e-2)" "unprognostic (2.20e-1)" "unprognostic (3.94e-2)" 0.4 0.5 0.1 6.7 0.1 17.8 1.6 0.3 0.2 1.0 7.7 4.6 4.7 1.2 0.3 5.2 0.6 0.6 0.3 0.3 0.1 0.3 0.4 1.0 12.6 0.0 0.1 0.2 0.2 0.2 0.1 3.4 0.1 0.4 6.0 0.1 0.9 0.2 0.0 3.5 4.1 2.1 0.0 3.1 2.4 22.2 0.2 35.7 0.5 0.0 15.0 1.5 1.7 0.0 66.5 32.8 103.0 41.5 2.5 7.1 33.2 60.9 34.2 64.6 55.7 48.1 25.0 59.7 33.5 22.7 59.0 72.6 98.8 33.2 70.5 51.8 52.1 86.4 83.6 45.5 0.2 79.0 45.7 1.6 2.0 39.2 37.1 12.9 47.7 66.5 76.4 61.7 65.6 22.5 62.5 48.9 70.2 55.6 36.8 66.5 83.7 45.2 19.9 33.1 67.1 40.8 38.0 35.9 13.3 45.1 41.9 40.9 27.6 49.3 51.8 49.2 55.5 32.1 58.2 95.6 26.3 87.8 65.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.1 0.2 1.1 0.0 0.1 0.0 0.1 0.0 0.8 0.0 0.1 0.1 0.1 0.3 0.2 0.3 0.1 0.0 0.1 0.1 0.0 0.2 0.0 0.1 3.2 1.1 0.3 1.8 0.8 0.3 1.0 1.8 0.7 0.9 2.0 0.8 0.0 1.9 0.0 0.0 5.4 0.6 1.8 0.0 0.4 3.0 0.9 1.4 1.0 0.0 23.5 0.7 0.0 6.7 2.4 5.6 2.1 0.0 12.9 1.1 0.3 5.2 0.0 0.7 2.5 0.0 1.9 1.7 3.3 1.5 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 1.5 0.4 12.6 0.3 0.3 0.1 0.2 0.2 6.6 0.2 1.7 79.2 26.8 6.9 0.3 0.8 1.8 0.8 5.4 0.6 C14orf39 SIX6OS1 ENSG00000179008 "Chromosome 14 open reading frame 39" Q8N1H7 14 60396469-60515543 "Plasma proteins, Predicted intracellular proteins" "DNA recombination, Meiosis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "pituitary gland: 4.8;salivary gland: 4.6;testis: 10.8" "Cell type enriched" "Detected in some" 4 "Spermatocytes: 92.5" "Cancer enhanced" "Detected in single" "testis cancer: 0.5" "Group enriched" "Detected in some" 16 "hypothalamus: 2.9;thalamus: 2.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 6.2;JURKAT: 28.3;MOLT-4: 23.9;RH-30: 6.2;U-2 OS: 12.7" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA059518 Uncertain Approved Nucleoplasm,Nucleoli Yes No "Cluster 77: Retina - Visual perception" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoplasm, Nucleoli" "HPA059518: AB_2684049" "unprognostic (6.17e-2)" "unprognostic (1.73e-3)" "unprognostic (3.00e-6)" "unprognostic (2.78e-1)" "unprognostic (6.97e-2)" "unprognostic (7.55e-4)" "unprognostic (2.12e-1)" "unprognostic (1.71e-1)" "unprognostic (2.17e-1)" "unprognostic (1.78e-1)" "unprognostic (7.46e-2)" "unprognostic (4.35e-1)" "unprognostic (1.50e-1)" "unprognostic (2.09e-1)" 0.3 1.8 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.2 0.8 0.4 0.2 0.5 0.0 0.1 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.1 0.0 0.1 0.1 1.2 0.0 0.5 4.8 0.0 0.0 1.1 0.0 2.7 4.6 0.1 3.0 0.0 0.1 0.1 0.0 0.0 0.3 10.8 2.4 0.1 0.2 3.7 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.8 6.2 0.0 0.0 0.0 0.0 0.3 4.5 0.0 0.7 0.0 0.1 0.0 28.3 0.0 0.0 2.0 0.0 23.9 0.3 3.0 0.0 1.4 0.0 6.2 0.0 0.4 1.7 0.1 2.6 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 12.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 2.9 0.1 0.1 0.0 0.0 2.4 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.6 0.5 0.0 0.9 0.0 0.1 0.7 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.0 0.0 0.0 0.2 0.0 0.0 2.8 0.0 0.0 0.3 0.0 0.0 1.3 0.0 0.0 0.0 0.0 3.3 0.9 0.0 0.0 0.0 0.0 6.8 0.3 0.0 0.0 1.0 0.0 12.3 0.0 1.0 0.7 0.0 0.0 0.7 0.0 0.8 0.0 0.0 1.2 1.1 0.0 10.0 0.2 92.5 19.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 C17orf75 "NJMU-R1, SRI2" ENSG00000108666 "Chromosome 17 open reading frame 75" Q9HAS0 17 32324565-32350023 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 88.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004061, HPA075333" Approved Approved Approved "Golgi apparatus,Cytosol" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Golgi apparatus, Cytosol" "HPA004061: AB_1078337, HPA075333: " "unprognostic (4.21e-2)" "unprognostic (2.49e-2)" "unprognostic (3.32e-2)" "unprognostic (2.28e-1)" "unprognostic (1.51e-1)" "unprognostic (4.73e-2)" "unprognostic (1.07e-3)" "unprognostic (6.36e-2)" "unprognostic (3.29e-1)" "prognostic favorable (3.13e-4)" "unprognostic (1.92e-2)" "unprognostic (7.80e-2)" "prognostic favorable (1.33e-4)" "unprognostic (3.09e-1)" "unprognostic (1.29e-1)" "unprognostic (4.27e-2)" "unprognostic (5.60e-2)" 8.1 15.9 10.9 10.4 11.4 7.5 13.2 12.1 13.5 8.9 12.3 11.7 13.3 12.4 18.7 8.7 15.0 7.0 19.4 10.8 11.7 21.3 14.5 8.7 12.9 11.2 10.9 16.1 13.2 27.8 13.4 10.4 11.8 11.6 12.6 26.1 12.2 10.6 17.5 7.2 10.8 10.4 10.5 9.5 12.9 26.3 11.1 16.0 14.1 14.3 13.2 9.6 8.2 11.2 39.2 33.4 51.0 15.5 13.3 14.5 27.9 25.5 22.4 34.3 29.1 18.2 14.9 23.5 28.6 18.2 52.6 42.5 32.8 27.6 46.6 18.0 37.9 18.7 39.8 39.5 26.6 26.3 14.1 13.4 33.0 25.2 17.4 28.6 25.3 43.6 38.9 31.8 22.8 29.2 76.5 26.9 37.7 23.9 14.7 50.1 31.5 44.0 21.4 18.2 50.4 44.3 21.1 19.1 62.7 37.2 50.4 16.8 19.8 18.8 35.4 9.3 42.4 42.5 51.0 82.9 15.3 23.0 5.7 34.6 12.4 16.4 17.6 12.0 20.1 18.2 16.9 18.3 16.1 19.9 18.2 17.0 3.2 19.0 17.1 12.8 19.6 15.4 10.9 11.4 12.1 13.5 10.8 11.7 11.2 10.9 11.8 10.5 11.1 11.2 12.6 12.8 30.7 7.2 13.8 5.9 13.4 27.8 12.5 25.0 11.3 13.5 25.8 8.6 19.3 14.7 8.4 31.8 10.7 3.8 43.0 16.2 10.0 17.2 8.8 10.5 12.6 13.5 11.1 13.8 18.0 9.8 9.7 10.5 11.4 18.3 6.4 11.0 9.7 32.0 15.0 8.0 28.5 7.5 3.7 6.3 7.5 7.8 5.4 2.8 6.7 17.5 11.3 10.1 8.7 11.8 3.2 8.2 14.0 6.4 6.9 29.9 29.9 23.0 39.5 9.7 13.1 88.0 31.8 12.0 6.1 16.3 15.1 10.5 8.4 8.2 C18orf63 DKFZP781G0119 ENSG00000206043 "Chromosome 18 open reading frame 63" Q68DL7 18 74315839-74359189 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 43 "testis: 9.8" "Cell type enriched" "Detected in some" 10 "Spermatocytes: 83.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA042233 Approved Mitochondria NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Mitochondria "HPA042233: AB_10960843" "unprognostic (1.40e-1)" "unprognostic (1.43e-4)" 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 83.7 7.9 0.0 0.0 0.0 0.0 0.1 0.1 0.0 C1orf112 FLJ10706 ENSG00000000460 "Chromosome 1 open reading frame 112" Q9NSG2 1 169662007-169854080 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 13.5" "Cell type enhanced" "Detected in many" "Microglial cells: 30.0;Spermatocytes: 37.1;Spermatogonia: 20.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA023778, HPA024451" Uncertain Approved Mitochondria NA NA "Cluster 15: NK-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Mitochondria "HPA023778: AB_1848665, HPA024451: AB_1848667" "unprognostic (4.97e-2)" "unprognostic (1.46e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (9.56e-5)" "unprognostic (1.33e-1)" "unprognostic (9.40e-2)" "unprognostic (2.50e-3)" "unprognostic (2.09e-1)" "unprognostic (9.11e-3)" "unprognostic (8.79e-2)" "unprognostic (3.47e-3)" "unprognostic (5.97e-2)" "unprognostic (1.65e-8)" "unprognostic (1.76e-1)" "unprognostic (2.81e-2)" "unprognostic (6.17e-2)" "unprognostic (2.63e-1)" 1.8 1.2 0.6 3.3 0.9 9.0 2.9 1.7 0.8 2.3 0.5 2.6 1.2 2.9 1.0 2.0 1.5 1.4 1.0 0.5 0.4 1.1 2.6 1.7 6.3 1.0 0.6 2.2 1.5 13.5 1.0 3.4 0.8 1.8 4.1 5.4 1.5 2.0 0.9 2.4 1.8 2.7 0.7 2.8 1.9 10.3 0.9 11.6 1.7 1.5 7.9 3.1 1.7 1.5 32.7 17.5 21.9 11.3 3.5 4.8 32.2 21.1 10.7 30.0 30.6 19.1 27.7 29.0 9.3 7.0 10.7 26.0 27.6 14.7 34.3 16.9 16.5 27.1 23.0 14.1 1.2 35.8 11.3 1.5 1.9 22.5 5.3 3.5 12.8 16.8 44.9 48.0 24.8 7.9 31.5 10.3 28.8 22.9 12.1 23.3 24.7 19.5 4.0 16.1 16.2 16.9 13.4 22.1 6.9 20.6 21.0 18.3 9.5 24.1 19.1 17.8 28.9 12.9 20.9 30.6 9.0 26.4 24.1 2.2 0.8 1.0 0.6 1.9 0.4 1.4 0.6 0.6 1.2 1.4 0.3 0.5 0.1 2.1 2.3 0.4 0.7 0.6 0.6 0.9 1.7 0.8 0.5 0.4 1.0 0.6 0.8 0.7 0.9 1.5 1.2 0.0 3.3 4.2 4.0 1.8 2.7 2.6 1.2 4.1 1.7 1.8 0.5 0.0 1.5 0.0 6.2 9.1 1.6 1.9 0.0 2.7 8.7 0.9 2.1 2.2 0.0 3.4 9.9 3.4 9.1 2.5 2.6 1.2 4.5 9.8 2.9 3.8 6.2 1.7 9.6 1.2 6.1 3.5 2.1 4.1 2.1 3.0 3.6 30.0 1.3 2.4 0.0 13.0 13.2 3.0 0.3 3.8 5.5 1.0 0.8 0.7 2.0 6.6 6.6 1.4 2.6 37.1 20.3 2.8 1.0 3.8 3.3 2.2 2.6 2.4 CBX1 "CBX, HP1-BETA, HP1Hs-beta, M31, MOD1" ENSG00000108468 "Chromobox 1" P83916 17 48070052-48101478 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 350.8;Spermatogonia: 304.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB012265 Supported Supported "Nucleoplasm,Nuclear bodies" NA NA 120000 "Cluster 1: Neutrophils - Mixed function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoplasm, Nuclear bodies" "CAB012265: AB_297216" "unprognostic (7.50e-2)" "unprognostic (3.33e-1)" "unprognostic (2.02e-1)" "unprognostic (2.58e-2)" "unprognostic (3.15e-1)" "unprognostic (3.04e-1)" "prognostic unfavorable (2.70e-4)" "unprognostic (2.68e-2)" "unprognostic (3.45e-2)" "unprognostic (6.55e-2)" "unprognostic (2.78e-1)" "unprognostic (2.72e-2)" "unprognostic (1.67e-2)" "unprognostic (6.48e-3)" "unprognostic (3.82e-1)" "unprognostic (3.65e-1)" "unprognostic (6.73e-2)" 30.9 31.4 60.3 35.5 59.9 16.5 37.2 61.6 73.2 53.6 54.5 40.7 19.0 66.5 47.9 36.8 40.2 27.9 32.1 59.8 63.9 37.9 21.6 26.9 35.0 63.2 59.7 77.5 22.3 43.8 34.8 34.7 64.0 38.0 33.1 59.5 29.7 47.1 68.4 28.8 24.0 55.6 64.9 33.7 26.6 69.1 60.3 73.6 39.5 46.0 46.9 36.4 37.9 67.3 217.3 121.1 392.4 185.6 78.0 69.3 217.7 197.0 95.1 188.0 200.6 319.2 84.5 148.4 204.5 155.6 144.8 85.3 146.3 124.6 329.2 273.8 118.1 119.8 121.1 119.3 47.5 115.5 71.9 49.8 68.4 140.3 178.3 144.7 157.1 176.6 152.0 67.2 153.8 135.7 325.9 79.8 150.6 118.8 156.9 241.8 322.7 95.8 110.3 121.7 138.5 345.6 135.0 44.6 75.5 281.8 211.0 82.5 110.7 260.2 238.9 112.0 201.1 94.0 227.9 140.4 71.4 50.4 119.0 5.1 12.2 16.0 12.4 12.7 10.0 16.1 11.2 10.4 9.9 15.7 11.5 9.7 33.6 9.5 9.3 10.6 12.4 5.9 60.3 59.9 61.6 73.2 59.8 63.9 63.2 59.7 64.0 64.9 60.3 67.3 32.9 67.3 27.6 7.8 31.4 43.6 30.5 46.1 36.5 46.9 48.0 54.7 70.9 18.6 33.6 42.3 20.9 66.4 27.5 19.2 35.2 68.7 26.8 40.8 78.9 40.2 40.3 34.3 13.0 29.7 86.6 61.5 10.2 39.6 39.9 65.3 30.0 15.6 69.6 50.5 15.5 27.3 42.7 33.5 24.5 59.5 80.2 26.7 40.9 7.5 47.7 106.6 42.2 12.5 13.7 34.7 12.9 91.7 20.0 51.1 9.6 30.9 32.2 36.3 39.5 33.3 71.8 350.8 304.0 26.7 36.2 27.8 25.6 35.8 28.6 20.1 CCDC73 NY-SAR-79 ENSG00000186714 "Coiled-coil domain containing 73" Q6ZRK6 11 32602246-32794658 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "testis: 3.7" "Group enriched" "Detected in some" 16 "Spermatocytes: 160.3;Spermatogonia: 84.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "MOLT-4: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA038668, HPA038669" Uncertain NA NA "Cluster 24: B-cells - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA038668: AB_10673292, HPA038669: AB_2676142" "unprognostic (9.41e-3)" "unprognostic (2.46e-2)" "unprognostic (2.36e-1)" "unprognostic (8.65e-2)" "unprognostic (5.79e-2)" "unprognostic (1.14e-2)" "unprognostic (1.89e-1)" "unprognostic (1.73e-4)" "unprognostic (1.74e-1)" "unprognostic (2.02e-2)" "unprognostic (2.10e-2)" "unprognostic (3.27e-2)" "unprognostic (1.62e-5)" "unprognostic (3.87e-1)" "unprognostic (1.02e-1)" "unprognostic (1.68e-1)" "unprognostic (1.20e-3)" 0.0 0.2 0.1 0.1 0.0 0.3 0.0 0.2 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.4 0.0 0.2 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.5 0.0 3.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.1 1.8 0.3 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.4 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.2 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 3.2 0.6 2.3 0.1 0.0 0.3 0.2 0.0 0.1 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.2 0.0 1.9 0.0 4.8 1.8 0.5 0.6 0.0 0.0 4.5 0.2 0.1 0.2 0.0 0.6 0.0 0.2 0.0 1.1 0.2 0.0 3.9 0.1 0.0 0.0 0.0 4.3 0.6 0.1 0.0 7.5 0.1 0.0 0.0 3.5 1.7 0.3 1.2 0.7 0.3 0.3 0.0 0.9 1.0 0.6 6.6 0.0 0.2 160.3 84.2 0.0 0.0 0.1 0.2 4.3 0.0 0.5 CCNE2 CYCE2 ENSG00000175305 "Cyclin E2" O96020 8 94879770-94896678 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 37.0" "Cell type enhanced" "Detected in many" "Erythroid cells: 33.6;Oligodendrocytes: 34.5;Spermatocytes: 77.7;Spermatogonia: 26.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 5.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Karpas-707: 101.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007825, CAB019374" Enhanced NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "CAB007825: AB_598148, CAB019374: " "unprognostic (1.80e-2)" "unprognostic (4.81e-2)" "unprognostic (7.49e-2)" "unprognostic (2.08e-2)" "unprognostic (2.36e-1)" "prognostic favorable (5.87e-4)" "unprognostic (8.37e-4)" "prognostic unfavorable (8.77e-4)" "unprognostic (3.18e-2)" "unprognostic (2.19e-2)" "unprognostic (3.64e-2)" "unprognostic (1.04e-2)" "unprognostic (7.01e-12)" "unprognostic (1.81e-2)" "unprognostic (1.50e-1)" "unprognostic (1.06e-2)" "unprognostic (3.03e-1)" 2.0 0.6 3.7 6.9 8.3 37.0 2.2 9.0 7.7 1.7 0.3 5.4 3.6 1.8 0.1 4.7 0.6 2.4 1.4 3.2 5.4 0.5 2.3 1.8 10.9 9.9 8.1 1.5 1.8 0.5 0.6 4.3 8.8 1.2 5.7 5.2 1.8 0.2 0.7 5.9 4.3 2.2 7.4 2.3 4.0 14.5 8.0 15.1 1.7 0.7 9.6 2.1 1.5 13.4 47.2 6.2 24.0 15.0 2.9 5.4 16.5 47.3 16.6 29.4 28.9 11.3 20.6 24.5 31.4 20.3 9.1 24.4 19.4 17.5 39.5 17.4 17.5 49.5 26.6 4.2 0.2 20.2 29.0 1.4 1.1 21.4 2.1 6.4 15.5 30.1 21.7 101.5 42.5 14.2 77.8 9.7 8.1 37.4 14.1 54.1 41.7 11.7 8.1 26.4 34.8 14.5 31.8 8.4 5.9 3.0 42.0 21.2 13.0 30.7 20.2 22.9 42.8 19.1 21.1 59.3 24.8 36.1 23.1 0.0 0.2 0.1 0.8 0.2 0.3 0.3 1.1 1.3 0.7 1.0 0.3 0.6 0.6 1.5 0.1 0.0 5.2 0.6 3.7 8.3 9.0 7.7 3.2 5.4 9.9 8.1 8.8 7.4 8.0 13.4 7.5 6.4 1.7 0.7 3.0 4.2 1.6 2.3 6.8 2.9 5.9 8.9 2.5 0.0 1.9 1.8 6.2 7.2 7.2 12.3 0.0 0.2 6.9 1.3 2.7 3.5 0.0 33.6 2.3 0.2 7.8 2.6 4.1 2.9 0.0 2.1 2.5 1.3 4.4 8.4 2.6 4.0 0.0 2.5 1.9 9.0 1.2 4.8 0.0 0.0 0.0 1.0 1.0 1.5 34.5 0.2 2.4 0.4 14.6 1.1 6.3 0.1 1.1 4.7 6.6 2.6 4.3 77.7 26.2 9.5 3.8 1.9 7.5 1.2 3.3 0.8 CCNYL1 FLJ40432 ENSG00000163249 "Cyclin Y like 1" Q8N7R7 2 207711540-207761839 "Predicted intracellular proteins" Cyclin "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 62.7;Paneth cells: 121.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "BEWO: 83.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046825 Approved Approved "Plasma membrane" Yes No "Cluster 33: Neutrophils - Chromatin organization" "Cluster 83: Testis - Spermatogenesis" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "HPA046825: AB_10963934" "unprognostic (2.59e-2)" "unprognostic (1.23e-1)" "unprognostic (1.03e-2)" "unprognostic (1.20e-3)" "unprognostic (1.78e-1)" "unprognostic (1.59e-1)" "unprognostic (1.31e-3)" "unprognostic (5.48e-2)" "unprognostic (1.65e-1)" "unprognostic (1.41e-2)" "unprognostic (7.12e-3)" "unprognostic (7.99e-2)" "unprognostic (3.92e-2)" "unprognostic (8.08e-2)" "unprognostic (7.91e-2)" "unprognostic (2.37e-2)" "unprognostic (1.96e-3)" 12.8 4.7 3.8 10.6 4.9 9.9 7.1 2.8 5.3 8.2 3.7 15.3 11.7 5.0 5.2 17.8 4.2 7.9 6.1 5.2 5.1 10.9 12.4 11.8 8.6 4.8 4.2 3.4 13.7 4.2 4.5 13.6 5.1 4.8 13.3 9.0 6.9 4.8 7.8 3.9 11.3 8.7 4.2 8.1 11.0 16.2 4.5 6.1 11.4 4.4 9.3 10.4 9.5 6.8 25.7 11.0 14.5 20.4 18.6 21.2 83.3 15.6 25.8 15.7 17.7 51.1 23.7 9.9 14.2 28.6 38.5 17.4 17.7 29.4 15.2 3.7 13.5 13.3 12.8 41.6 18.7 11.9 15.2 10.7 12.0 20.0 20.9 13.8 52.5 11.5 6.8 9.4 21.9 13.6 10.5 11.2 28.1 10.3 12.2 9.4 12.4 8.0 16.2 19.5 3.5 10.8 18.5 8.0 23.5 33.6 7.2 31.5 27.3 17.7 16.6 23.2 10.5 5.6 8.4 13.4 18.5 13.5 15.4 0.7 1.1 0.5 0.3 0.6 0.4 0.3 0.5 0.5 0.5 1.1 0.4 0.8 1.3 0.6 0.5 0.5 0.4 0.3 3.8 4.9 2.8 5.3 5.2 5.1 4.8 4.2 5.1 4.2 4.5 6.8 31.8 3.2 19.1 10.1 14.1 12.2 13.8 7.6 5.7 6.2 10.0 10.0 9.0 2.8 8.5 23.9 10.4 12.6 13.2 62.7 1.9 5.8 13.7 13.6 7.7 17.0 9.6 6.5 34.1 14.7 42.9 11.4 25.0 20.4 5.7 5.8 23.9 12.5 16.2 5.0 11.6 13.1 8.2 17.5 29.9 10.9 2.8 18.7 8.8 7.5 20.8 10.2 7.2 14.6 28.7 13.9 121.3 3.8 7.7 16.1 10.1 12.6 6.3 12.3 0.0 16.0 10.4 23.9 9.5 7.6 10.5 7.7 10.9 4.3 17.0 18.0 CCP110 "CP110, KIAA0419" ENSG00000103540 "Centriolar coiled-coil protein 110" O43303 16 19523811-19553408 "Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 48.1" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 210.2;Respiratory ciliated cells: 118.8;Spermatocytes: 169.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039402 Approved Approved "Centriolar satellite" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 14: REH - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Centriolar satellite" "HPA039402: AB_10671041" "unprognostic (2.83e-1)" "unprognostic (2.41e-2)" "unprognostic (3.08e-2)" "unprognostic (2.97e-1)" "unprognostic (1.65e-1)" "unprognostic (2.82e-1)" "unprognostic (4.88e-2)" "unprognostic (9.68e-2)" "unprognostic (3.25e-2)" "unprognostic (2.68e-1)" "unprognostic (6.50e-2)" "unprognostic (1.92e-2)" "unprognostic (8.99e-3)" "unprognostic (2.74e-2)" "unprognostic (1.82e-1)" "unprognostic (3.01e-2)" "unprognostic (1.37e-1)" 5.6 5.9 23.6 6.6 41.3 15.7 9.2 22.7 34.5 7.3 11.4 5.5 3.9 9.2 7.3 6.6 13.3 5.9 4.7 22.6 25.1 4.5 3.6 8.6 8.2 27.4 30.2 10.5 4.0 11.5 11.8 4.9 25.2 7.3 5.6 13.8 5.2 6.9 5.0 5.9 4.9 7.9 18.6 6.4 6.4 35.8 30.7 16.5 7.1 5.8 7.7 6.2 5.2 48.1 22.4 10.2 24.7 24.1 12.1 10.7 12.7 23.4 13.5 20.4 22.9 8.3 11.7 32.8 14.5 11.6 15.5 15.4 25.6 7.4 34.2 15.1 11.6 16.4 14.5 14.3 6.0 42.6 20.2 5.3 10.0 23.0 14.0 12.6 15.9 33.1 17.5 16.0 24.1 17.3 43.8 16.5 19.0 10.7 7.6 55.1 46.1 11.5 9.3 9.3 48.5 24.5 25.4 11.9 7.6 16.4 21.9 25.6 9.5 23.7 15.6 16.0 19.5 17.6 17.7 23.5 15.2 18.0 14.1 14.5 2.8 5.2 3.8 2.7 2.4 2.5 3.4 3.7 3.0 3.2 3.8 2.2 5.5 1.7 4.3 2.0 2.9 2.0 23.6 41.3 22.7 34.5 22.6 25.1 27.4 30.2 25.2 18.6 30.7 48.1 9.3 32.1 34.6 19.9 12.7 13.5 9.2 10.8 14.8 18.1 16.4 11.2 14.7 8.6 27.6 23.9 33.3 11.4 19.4 6.9 5.9 9.2 5.1 75.1 19.5 10.7 1.2 46.3 30.6 4.7 7.0 15.7 10.2 13.5 30.3 12.5 12.1 7.5 7.0 30.3 30.9 9.9 6.1 18.2 12.8 9.0 21.1 10.7 10.6 13.1 11.6 14.5 12.3 21.1 210.2 9.0 6.0 16.6 12.7 9.2 8.0 5.3 118.8 66.0 19.7 22.5 12.5 169.2 38.6 13.3 14.6 24.5 14.4 9.5 6.1 6.9 CCT3 "Cctg, TRIC5" ENSG00000163468 "Chaperonin containing TCP1 subunit 3" P49368 1 156308968-156367873 "Plasma proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006543 Approved Approved "Plasma membrane,Cytosol" NA NA 1300000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Plasma membrane, Cytosol" "HPA006543: AB_1078426" "unprognostic (2.14e-2)" "unprognostic (3.20e-3)" "unprognostic (1.66e-1)" "unprognostic (6.00e-3)" "unprognostic (8.39e-3)" "unprognostic (3.14e-3)" "prognostic unfavorable (3.87e-7)" "unprognostic (4.43e-3)" "unprognostic (2.78e-1)" "unprognostic (1.16e-1)" "unprognostic (5.44e-2)" "unprognostic (1.74e-1)" "prognostic unfavorable (6.34e-4)" "unprognostic (7.16e-2)" "unprognostic (5.76e-2)" "unprognostic (5.67e-2)" "unprognostic (1.10e-1)" 85.3 122.3 121.4 103.0 125.8 79.5 119.4 132.2 176.7 77.1 139.0 95.3 87.2 93.6 77.1 106.9 119.9 67.4 100.8 125.3 135.5 114.5 108.3 60.1 123.9 129.4 126.1 113.5 82.3 120.4 65.3 93.3 129.5 86.6 112.9 135.7 74.9 89.8 134.8 93.8 83.3 137.3 132.4 67.1 80.7 120.3 130.2 129.1 87.6 120.8 148.5 136.7 70.6 143.8 432.3 562.3 324.3 311.9 352.5 261.2 419.7 388.8 315.9 617.9 378.0 611.1 396.3 689.5 442.3 337.9 392.5 395.5 1045.2 519.9 519.1 384.3 660.6 437.6 438.6 579.2 261.9 547.7 357.2 333.7 312.4 556.6 514.7 303.3 531.6 425.3 795.2 250.1 375.5 603.5 688.2 372.1 656.4 859.5 702.1 587.3 314.5 771.1 496.9 349.9 434.9 448.1 347.0 635.0 388.7 531.0 560.2 707.3 366.1 249.0 373.0 263.3 717.1 457.5 808.2 975.7 288.1 349.1 408.1 75.1 107.1 49.0 129.0 137.0 171.2 142.1 144.3 138.8 171.7 156.8 177.0 156.7 14.9 145.8 146.8 120.8 164.3 222.3 121.4 125.8 132.2 176.7 125.3 135.5 129.4 126.1 129.5 132.4 130.2 143.8 82.8 54.5 62.5 18.3 104.8 144.9 241.1 247.4 119.5 124.5 133.2 118.5 121.1 98.7 132.3 90.1 106.3 226.7 100.5 71.7 113.5 208.6 111.9 118.4 137.4 122.4 125.3 134.0 29.7 183.2 217.8 113.9 70.8 86.6 73.0 180.1 74.6 88.4 162.6 74.0 34.6 93.8 193.3 83.0 96.5 226.7 83.6 78.1 112.1 22.5 153.6 158.1 105.0 37.2 41.9 199.1 78.8 88.0 95.8 169.0 115.9 212.3 137.6 244.3 118.3 110.3 145.4 410.0 232.4 123.1 159.8 184.6 112.1 347.9 149.8 157.9 CDC6 CDC18L ENSG00000094804 "Cell division cycle 6" Q99741 17 40287879-40304657 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA replication, Mitosis" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 27.2;lymphoid tissue: 17.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 23.2;Erythroid cells: 37.2;Extravillous trophoblasts: 34.6;Plasma cells: 31.6;Spermatocytes: 69.5;Spermatogonia: 57.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 3.6" "Group enriched" "Detected in many" 6 "dendritic cells: 3.6;NK-cells: 1.5;T-cells: 2.4" "Cell line enhanced" "Detected in all" "SK-BR-3: 500.3" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA050114, HPA065070" Approved Approved "Nucleoplasm,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cytosol" "Cytokinetic bridge, Mitotic spindle" "HPA050114: AB_2681021, HPA065070: AB_2732729" "unprognostic (1.29e-1)" "unprognostic (7.22e-2)" "unprognostic (1.23e-3)" "unprognostic (7.97e-2)" "unprognostic (7.12e-2)" "unprognostic (2.89e-2)" "prognostic unfavorable (5.96e-8)" "unprognostic (2.31e-3)" "unprognostic (1.46e-3)" "unprognostic (1.41e-1)" "prognostic unfavorable (2.90e-4)" "unprognostic (5.47e-2)" "unprognostic (3.00e-15)" "unprognostic (1.86e-2)" "unprognostic (1.35e-1)" "unprognostic (3.95e-3)" "unprognostic (3.88e-2)" 2.1 1.9 0.5 13.7 0.8 27.2 3.4 0.2 1.9 3.2 0.0 8.4 7.5 2.2 1.1 5.7 1.0 2.8 0.6 1.1 0.1 0.5 3.0 1.4 16.4 0.1 0.0 0.9 1.9 0.8 0.5 9.3 0.3 1.1 8.7 0.5 1.3 1.2 0.3 2.8 6.7 3.7 0.0 3.7 3.6 10.1 0.2 16.7 1.7 0.5 17.1 4.3 1.8 0.6 155.1 119.0 115.1 86.5 6.7 12.7 118.0 159.9 49.0 149.2 166.5 135.8 64.9 123.9 99.6 35.9 85.9 214.0 112.2 76.2 148.9 64.5 98.4 96.2 122.3 134.6 4.4 133.3 55.1 4.7 8.1 156.4 107.1 14.8 46.9 84.2 183.0 109.0 71.9 95.8 199.3 43.3 101.6 96.9 48.7 145.0 286.8 119.9 30.3 184.8 85.6 76.9 146.9 500.3 55.4 100.3 100.8 120.0 34.7 95.5 146.3 170.8 196.1 46.1 103.6 222.8 84.6 93.9 109.2 0.1 0.1 0.0 0.8 0.0 0.5 0.4 0.6 1.1 0.7 0.3 0.4 1.1 0.1 1.5 0.0 3.6 2.4 0.6 0.5 0.8 0.2 1.9 1.1 0.1 0.1 0.0 0.3 0.0 0.2 0.6 2.2 0.0 2.0 0.7 4.9 4.2 1.1 3.7 3.4 0.2 2.1 2.2 0.9 1.5 1.3 0.0 0.0 23.2 2.3 7.8 0.0 1.3 2.2 1.3 2.9 2.1 0.0 37.2 2.0 0.6 34.6 5.6 3.6 5.1 0.0 8.1 1.1 0.9 8.3 0.0 0.7 6.1 0.0 1.3 2.1 1.0 2.8 1.5 0.0 0.0 0.0 0.4 2.1 0.0 0.2 1.5 3.0 0.7 31.6 1.3 0.8 0.2 0.2 0.3 13.1 0.6 4.6 69.5 57.2 9.1 1.6 16.7 3.3 1.9 9.3 2.4 CDCA8 "BOR, DasraB, FLJ12042, MESRGP" ENSG00000134690 "Cell division cycle associated 8" Q53HL2 1 37692481-37709719 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 33.5;lymphoid tissue: 38.8;testis: 22.5" "Cell type enhanced" "Detected in many" "Erythroid cells: 34.1;Extravillous trophoblasts: 26.0;Spermatocytes: 76.8;Spermatogonia: 42.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA028120, HPA028258, HPA028783, CAB040294" Enhanced Supported "Nucleoplasm,Nucleoli,Cytokinetic bridge" Yes Yes "Cluster 27: Non-specific - Gene expression" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoli "Nucleoplasm, Cytokinetic bridge" "CAB040294: , HPA028120: AB_10670556, HPA028258: AB_10669864, HPA028783: AB_10671092" "unprognostic (8.36e-2)" "unprognostic (2.00e-1)" "unprognostic (8.39e-2)" "unprognostic (7.75e-3)" "unprognostic (2.34e-1)" "unprognostic (5.42e-2)" "prognostic unfavorable (4.93e-10)" "unprognostic (4.30e-3)" "prognostic unfavorable (6.04e-4)" "unprognostic (3.00e-1)" "prognostic unfavorable (8.32e-4)" "unprognostic (3.78e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (6.39e-3)" "unprognostic (2.99e-1)" "unprognostic (3.18e-1)" "unprognostic (1.67e-1)" 1.0 1.1 0.7 7.9 1.0 33.5 2.0 0.2 0.9 1.7 0.0 9.4 8.3 1.3 1.8 9.2 1.0 1.1 0.6 0.5 0.4 0.8 1.3 1.5 19.5 0.6 0.4 0.6 0.8 0.5 0.6 4.4 0.5 0.7 11.3 1.9 1.8 0.5 0.3 6.3 7.3 2.8 0.3 4.9 4.9 22.5 0.6 38.8 0.6 0.5 22.7 2.0 2.9 0.7 108.5 45.5 84.4 62.1 3.6 7.0 57.2 79.6 39.5 137.2 96.6 71.9 78.8 130.2 31.5 50.5 54.5 59.4 97.8 52.4 141.9 86.8 44.9 116.8 49.2 57.3 0.8 113.8 58.4 2.8 3.8 77.1 67.3 15.3 60.9 91.1 100.7 135.6 99.1 47.7 106.1 68.9 98.8 61.7 62.8 102.2 115.6 74.4 31.0 43.8 75.4 33.3 87.5 40.6 52.4 71.7 60.1 42.4 37.3 67.8 70.6 39.2 126.0 91.4 128.1 176.3 31.6 104.7 79.6 0.0 0.7 1.3 1.5 1.6 2.8 1.7 3.6 2.2 0.7 1.4 1.1 2.3 3.0 4.1 3.9 1.2 5.9 1.7 0.7 1.0 0.2 0.9 0.5 0.4 0.6 0.4 0.5 0.3 0.6 0.7 0.8 0.0 0.5 1.3 4.8 3.3 0.8 2.4 1.8 1.3 1.9 1.5 0.7 2.8 0.4 0.0 0.0 17.1 1.9 12.4 0.0 1.2 1.0 1.7 1.6 1.9 3.6 34.1 1.2 0.6 26.0 2.9 6.6 2.5 0.0 12.0 3.6 1.0 11.6 1.7 0.9 8.2 2.0 3.5 1.9 2.8 1.5 3.7 1.8 0.0 1.6 0.1 2.1 0.5 0.9 2.4 4.0 1.2 15.8 1.3 1.9 0.6 4.7 1.0 19.7 0.2 6.3 76.8 42.0 17.1 2.7 2.9 5.5 1.2 13.2 1.2 CENPE "KIF10, PPP1R61" ENSG00000138778 "Centromere protein E" Q02224 4 103105349-103198445 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Developmental protein, Motor protein" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 10.0;lymphoid tissue: 9.2" "Cell type enhanced" "Detected in many" "Erythroid cells: 75.1;Extravillous trophoblasts: 28.4;Granulosa cells: 32.0;Spermatocytes: 75.3;Spermatogonia: 51.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "basophil: 2.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA011110, HPA042294" Enhanced Enhanced "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes Yes "Cluster 46: Basophils - DNA binding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Microtubules "Cytokinetic bridge, Mitotic spindle" "HPA011110: , HPA042294: AB_10797386" "unprognostic (1.62e-1)" "unprognostic (1.03e-1)" "unprognostic (5.64e-3)" "unprognostic (2.55e-2)" "unprognostic (1.65e-1)" "unprognostic (3.44e-2)" "unprognostic (2.40e-8)" "unprognostic (2.49e-3)" "unprognostic (1.59e-2)" "unprognostic (3.38e-1)" "unprognostic (4.88e-5)" "unprognostic (1.15e-2)" "unprognostic (0.00e+0)" "unprognostic (9.95e-3)" "unprognostic (2.49e-1)" "unprognostic (1.05e-1)" "unprognostic (2.37e-1)" 0.4 0.2 0.4 2.7 0.4 10.0 0.6 0.3 0.5 0.4 0.4 1.8 1.5 0.6 0.0 2.0 0.2 0.8 0.2 0.3 0.6 0.2 0.5 0.8 5.6 0.5 0.5 0.1 0.1 0.3 0.0 1.4 0.9 0.3 2.0 0.4 0.3 0.2 0.0 2.0 1.7 1.1 0.3 1.2 1.1 4.1 0.5 9.2 0.2 0.6 4.9 0.8 0.6 0.5 42.6 11.8 42.2 20.5 2.7 6.2 8.4 36.7 18.2 26.9 17.9 19.6 22.2 28.6 9.2 13.7 19.2 18.2 30.3 15.1 42.2 35.9 11.3 33.5 26.8 13.6 0.4 39.9 18.6 1.8 1.1 21.7 18.0 6.0 22.9 25.2 34.4 32.5 34.8 15.6 31.5 18.9 13.8 17.0 17.9 20.9 38.5 9.3 8.0 8.4 19.3 11.5 32.9 22.9 9.0 16.0 12.9 13.9 26.1 25.8 27.2 27.2 38.6 15.9 28.6 28.8 14.2 21.7 27.8 2.9 0.0 0.3 0.0 0.2 0.0 0.2 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.3 1.5 0.2 0.6 0.0 0.4 0.4 0.3 0.5 0.3 0.6 0.5 0.5 0.9 0.3 0.5 0.5 1.4 3.2 2.2 1.0 6.6 3.6 1.5 2.9 0.0 7.6 1.8 2.7 1.9 0.0 1.3 0.0 8.4 12.7 3.9 4.7 0.0 0.5 7.7 3.5 5.7 4.2 1.2 75.1 2.0 0.0 28.4 6.5 4.6 6.9 7.0 32.0 4.2 0.9 14.1 0.0 1.9 4.3 4.1 10.4 5.7 3.5 0.9 9.6 0.0 0.0 6.0 1.3 2.1 0.5 3.1 1.8 1.4 2.6 16.0 1.4 0.8 0.3 0.3 2.6 0.0 5.7 7.4 75.3 51.0 8.3 2.8 3.6 6.6 7.0 11.6 1.9 CENPH ENSG00000153044 "Centromere protein H" Q9H3R5 5 69189574-69210357 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 33.8;testis: 29.7" "Cell type enhanced" "Detected in many" "Erythroid cells: 74.5;Spermatocytes: 222.7;Spermatogonia: 222.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" HPA036494 Approved Supported "Nucleoplasm,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 15: NK-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nucleoli rim" "Mitotic chromosome" "HPA036494: AB_10673354" "unprognostic (1.49e-1)" "prognostic favorable (6.86e-4)" "unprognostic (1.73e-2)" "unprognostic (3.16e-2)" "unprognostic (2.32e-1)" "unprognostic (3.87e-2)" "prognostic unfavorable (5.22e-5)" "unprognostic (6.14e-3)" "unprognostic (6.85e-2)" "prognostic favorable (2.50e-4)" "unprognostic (4.21e-2)" "unprognostic (8.80e-2)" "prognostic unfavorable (5.11e-15)" "unprognostic (1.17e-1)" "unprognostic (3.94e-1)" "unprognostic (2.58e-1)" "unprognostic (2.20e-1)" 4.2 2.0 1.4 7.5 1.7 33.8 7.7 1.7 2.0 3.9 1.0 7.4 6.5 4.5 2.1 7.5 4.0 1.8 4.0 1.5 1.6 1.6 3.6 2.8 17.7 1.6 1.5 3.9 1.5 2.0 1.4 5.2 1.6 3.3 8.1 2.5 2.9 2.3 4.0 9.2 5.9 3.7 1.4 5.2 3.7 29.7 1.6 18.5 2.5 4.0 18.8 3.8 4.4 2.2 64.6 19.4 88.6 70.2 5.8 18.3 48.0 31.2 32.6 66.9 71.8 26.5 79.6 138.9 36.6 18.1 39.1 47.0 59.0 70.4 85.1 42.7 41.4 32.7 32.5 26.4 2.0 47.1 32.1 7.1 14.6 43.6 47.7 18.9 23.2 73.7 58.7 53.3 52.2 35.6 152.4 67.3 78.1 20.7 17.0 93.2 118.2 108.2 21.1 22.9 61.6 81.9 34.6 22.8 27.5 47.7 31.9 31.4 11.4 33.4 56.1 44.5 78.7 65.5 106.3 111.8 51.1 94.2 64.7 1.0 2.0 3.0 4.7 3.5 7.7 13.3 7.9 6.0 3.1 14.1 9.9 8.6 0.4 8.6 4.2 6.7 9.7 4.8 1.4 1.7 1.7 2.0 1.5 1.6 1.6 1.5 1.6 1.4 1.6 2.2 4.8 0.0 2.6 1.0 18.3 36.7 17.7 17.4 9.6 3.4 10.8 11.7 3.3 4.3 7.1 0.0 0.0 37.4 9.2 5.1 0.0 12.3 26.5 5.5 5.1 6.9 1.2 74.5 1.3 9.1 49.0 7.4 2.6 4.8 5.1 22.4 4.6 1.1 17.0 0.0 1.1 9.5 12.2 7.5 18.2 22.5 3.7 6.3 8.8 1.0 4.3 7.3 6.2 1.0 0.9 7.0 2.5 4.9 14.4 6.9 1.4 3.4 10.8 3.5 19.7 6.4 9.3 222.7 222.8 12.1 19.2 10.0 12.0 6.9 15.9 15.2 CENPK "CENP-K, FKSG14, SOLT" ENSG00000123219 "Centromere protein K" Q9BS16 5 65517766-65563168 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 24.6;lymphoid tissue: 22.2" "Cell type enhanced" "Detected in many" "Erythroid cells: 50.9;Extravillous trophoblasts: 50.6;Spermatocytes: 101.3;Spermatogonia: 75.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA Yes "Cluster 20: T-cells - T-cell receptor" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "unprognostic (4.04e-2)" "unprognostic (1.77e-2)" "unprognostic (1.57e-2)" "unprognostic (5.04e-2)" "unprognostic (1.85e-1)" "unprognostic (3.04e-3)" "unprognostic (3.69e-4)" "unprognostic (3.22e-3)" "unprognostic (9.59e-3)" "unprognostic (3.32e-2)" "unprognostic (3.16e-3)" "unprognostic (1.98e-2)" "unprognostic (6.33e-15)" "unprognostic (2.22e-1)" "unprognostic (2.97e-1)" "unprognostic (8.42e-2)" "unprognostic (3.11e-1)" 1.1 0.9 0.6 10.6 0.7 24.6 3.8 1.0 0.8 1.2 1.6 9.0 8.3 1.9 0.9 5.6 2.3 1.9 0.5 0.5 0.6 0.8 1.9 2.0 14.6 1.0 0.7 0.8 0.6 1.0 0.3 5.5 1.1 1.3 11.9 0.7 1.4 0.7 0.2 8.6 8.6 3.4 0.7 4.5 5.5 13.4 1.0 22.2 1.2 0.5 12.4 2.6 2.4 1.4 65.3 41.4 85.6 29.5 4.4 12.0 40.8 69.8 26.5 58.7 73.6 35.1 97.2 39.3 25.2 23.6 59.5 39.7 33.3 35.4 92.7 45.2 28.5 42.1 50.7 33.8 1.7 50.1 36.8 5.6 5.0 56.9 27.3 10.6 56.4 42.2 31.8 57.7 59.1 21.5 85.4 56.2 41.1 18.5 17.1 52.5 81.9 43.8 38.8 34.4 35.8 28.9 53.7 22.1 28.7 31.8 40.0 36.9 20.3 44.9 46.5 31.1 82.2 30.0 51.9 83.0 41.9 74.0 49.9 3.7 0.7 2.3 9.9 1.0 14.8 4.0 21.1 12.5 1.7 7.0 28.5 20.2 1.7 10.2 1.1 1.6 23.2 10.0 0.6 0.7 1.0 0.8 0.5 0.6 1.0 0.7 1.1 0.7 1.0 1.4 2.7 0.0 3.4 0.3 11.7 23.6 8.5 14.0 4.6 1.6 6.0 7.9 0.9 0.0 8.1 0.0 0.0 28.8 18.7 5.8 1.9 3.1 27.6 25.5 4.5 5.7 0.0 50.9 3.1 1.0 50.6 6.3 9.2 7.2 2.5 22.7 3.9 1.1 22.4 0.0 2.3 14.7 8.2 1.9 12.0 17.4 1.5 5.7 1.8 11.2 1.8 0.6 7.2 2.0 1.4 2.3 2.1 1.5 14.1 2.2 1.1 0.3 7.1 1.1 0.0 2.3 9.1 101.3 75.1 17.0 8.1 6.7 20.7 3.9 15.8 11.4 CEP78 "C9orf81, FLJ12643" ENSG00000148019 "Centrosomal protein 78" Q5JTW2 9 78236062-78279690 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Cone-rod dystrophy, Deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 110.5;dendritic cells: 106.8;NK-cells: 249.3;Spermatocytes: 82.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 39.1" "Group enriched" "Detected in many" 5 "NK-cells: 39.1;T-cells: 18.3" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048846 Approved NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 63: NK-cells & T-cells - Immune response" "HPA048846: AB_2680537" "unprognostic (4.62e-1)" "unprognostic (6.33e-3)" "unprognostic (2.87e-2)" "unprognostic (1.36e-2)" "unprognostic (2.16e-1)" "unprognostic (1.36e-2)" "unprognostic (5.13e-4)" "unprognostic (6.75e-2)" "unprognostic (8.48e-3)" "unprognostic (2.10e-1)" "unprognostic (1.38e-2)" "unprognostic (7.03e-2)" "unprognostic (1.25e-2)" "unprognostic (2.27e-3)" "unprognostic (4.93e-1)" "unprognostic (1.18e-3)" "unprognostic (3.34e-1)" 2.2 2.9 4.3 4.6 5.0 12.3 4.3 5.9 4.4 4.1 3.8 3.5 2.8 5.6 3.2 3.5 3.4 2.4 1.6 4.2 4.7 3.6 3.5 3.4 6.2 4.6 4.5 4.3 2.5 4.3 2.7 3.9 4.6 3.1 3.9 9.2 3.3 3.4 1.6 3.5 2.9 4.7 5.1 5.0 3.0 15.1 4.3 11.5 3.7 1.7 7.7 3.2 3.0 6.2 31.7 14.5 33.3 20.5 5.4 9.4 22.3 25.6 10.1 15.1 19.1 2.7 8.4 28.9 12.7 9.2 21.4 36.9 49.6 13.7 22.5 24.3 16.6 15.4 17.1 11.4 4.9 26.0 14.6 5.2 2.9 17.1 11.1 7.5 23.4 29.4 12.2 22.4 19.8 20.3 32.6 12.8 35.2 32.7 14.0 32.2 38.4 8.4 9.0 14.0 30.4 21.1 33.7 10.6 8.4 22.7 12.6 6.9 12.5 13.3 22.6 27.5 24.7 13.1 17.8 18.4 11.8 17.6 23.0 0.7 0.8 0.7 18.3 3.4 8.9 5.0 7.9 16.0 2.3 3.4 3.9 12.8 0.5 39.1 5.5 4.2 13.1 8.3 4.3 5.0 5.9 4.4 4.2 4.7 4.6 4.5 4.6 5.1 4.3 6.2 10.3 25.6 9.2 26.1 13.7 5.1 8.1 6.9 8.0 27.1 7.6 10.5 8.9 4.3 7.2 1.8 110.5 14.0 106.8 3.9 5.9 8.4 14.1 18.7 16.9 9.0 7.7 25.7 28.6 6.7 19.5 10.3 10.2 10.4 5.1 20.6 7.1 9.0 9.6 3.3 20.5 8.0 4.1 6.1 6.1 9.9 14.9 10.0 1.8 9.4 9.7 14.7 249.3 27.2 24.6 4.7 4.1 15.1 43.7 3.7 1.0 5.1 22.1 49.4 0.0 14.8 11.3 82.1 34.2 10.0 4.8 4.0 34.0 12.3 13.2 4.0 CEP85 "CCDC21, DKFZP434L0117" ENSG00000130695 "Centrosomal protein 85" Q6P2H3 1 26234200-26278808 "Predicted intracellular proteins" "Chromosome partition" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 132.9;tongue: 65.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 29.0;Oligodendrocytes: 28.8;Spermatocytes: 40.9;Spermatogonia: 34.2;Syncytiotrophoblasts: 41.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 19.2" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028252 Approved Approved "Nucleoli,Golgi apparatus,Centrosome,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoli, Golgi apparatus" "Centrosome, Cytosol" "HPA028252: AB_1846142" "unprognostic (1.08e-1)" "unprognostic (2.59e-2)" "unprognostic (1.74e-2)" "unprognostic (4.16e-2)" "unprognostic (2.66e-1)" "unprognostic (5.30e-3)" "prognostic unfavorable (4.39e-6)" "unprognostic (3.72e-2)" "unprognostic (5.30e-2)" "unprognostic (8.24e-2)" "unprognostic (9.18e-2)" "unprognostic (1.57e-1)" "unprognostic (1.29e-1)" "unprognostic (7.33e-3)" "unprognostic (5.41e-2)" "unprognostic (1.02e-2)" "unprognostic (2.60e-2)" 2.8 3.5 3.9 5.3 8.3 20.8 3.8 5.6 6.7 4.1 3.7 5.4 3.4 3.2 3.2 8.6 2.7 2.7 25.5 4.3 5.9 6.0 5.8 4.7 6.9 7.1 6.8 3.3 5.0 8.8 6.1 3.2 8.9 2.9 6.0 14.1 5.3 2.4 132.9 9.8 5.2 3.7 3.7 6.3 4.7 31.1 7.1 13.6 7.8 65.9 7.8 3.2 6.2 14.3 29.6 12.5 30.2 22.6 7.3 8.9 52.5 18.8 11.5 31.9 28.5 17.4 28.2 34.3 20.1 9.2 14.6 25.5 41.0 14.4 29.9 23.5 20.9 49.7 31.9 19.4 6.6 46.2 43.8 3.8 13.7 24.9 16.4 12.8 14.5 47.7 57.4 39.9 19.2 9.8 38.7 35.2 23.0 17.4 20.8 39.8 31.3 29.7 10.4 5.5 41.4 16.7 24.5 19.8 15.7 21.5 14.5 26.4 14.3 17.1 26.7 19.3 24.7 30.0 48.4 38.9 9.8 65.2 27.5 5.0 6.4 19.2 3.5 6.1 2.8 2.6 2.6 2.7 4.9 1.8 2.2 3.5 0.6 2.3 7.4 2.1 3.6 3.6 3.9 8.3 5.6 6.7 4.3 5.9 7.1 6.8 8.9 3.7 7.1 14.3 1.0 0.0 2.2 3.6 2.7 6.9 4.0 2.5 6.2 11.2 3.7 2.9 29.0 1.5 3.7 5.5 12.5 3.4 5.1 6.9 7.9 1.7 1.0 3.4 2.3 2.0 1.8 16.8 12.8 1.3 3.9 2.3 3.6 4.9 2.5 9.1 1.4 3.1 4.8 0.0 9.9 3.7 2.0 5.0 3.7 2.9 1.5 4.3 1.8 4.7 4.0 1.8 2.1 3.0 28.8 2.7 3.4 0.4 4.4 2.5 2.3 1.1 2.0 11.1 0.0 2.4 2.3 40.9 34.2 8.6 6.1 41.7 3.4 2.3 4.5 4.5 CHEK1 CHK1 ENSG00000149554 "Checkpoint kinase 1" O14757 11 125625665-125676255 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 25.7;lymphoid tissue: 20.7;seminal vesicle: 29.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 32.9;Erythroid cells: 34.5;Extravillous trophoblasts: 35.6;Spermatocytes: 48.9;Spermatogonia: 49.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "T-reg: 6.2" "Group enriched" "Detected in many" 5 "granulocytes: 1.7;T-cells: 6.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA044364 Supported Nucleoplasm,Vesicles NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Vesicles "HPA044364: AB_2678913" "unprognostic (6.74e-2)" "unprognostic (3.63e-1)" "prognostic favorable (3.62e-4)" "unprognostic (5.54e-2)" "unprognostic (2.17e-1)" "unprognostic (1.03e-1)" "prognostic unfavorable (3.70e-6)" "unprognostic (3.95e-3)" "unprognostic (1.26e-3)" "unprognostic (2.54e-2)" "prognostic unfavorable (3.10e-6)" "unprognostic (1.75e-1)" "prognostic unfavorable (1.04e-8)" "unprognostic (2.89e-2)" "unprognostic (2.64e-1)" "unprognostic (8.16e-2)" "unprognostic (1.33e-1)" 1.6 1.3 0.7 8.2 1.0 25.7 2.6 0.6 1.3 1.7 0.5 7.9 6.8 1.7 6.7 4.1 1.1 1.7 0.9 0.7 0.9 2.2 2.1 1.3 14.9 0.7 0.8 1.8 2.0 13.2 1.7 4.8 0.8 1.6 8.7 0.7 1.5 29.8 0.6 3.6 7.3 3.4 0.6 2.2 2.6 8.9 1.2 20.7 1.0 1.3 13.9 3.3 2.1 0.8 48.5 37.0 81.1 47.4 13.5 28.9 35.7 61.1 28.7 41.6 40.1 88.0 100.3 120.7 63.5 24.9 53.7 52.6 54.2 33.2 50.1 81.4 24.8 224.2 27.2 44.7 4.3 121.1 39.6 15.7 6.0 47.6 36.0 19.9 44.7 84.1 117.3 102.7 51.4 23.8 181.3 65.0 86.1 77.1 33.2 104.7 74.4 67.2 37.9 63.2 50.5 53.6 45.2 35.4 15.2 57.3 93.9 40.6 28.4 51.0 47.3 29.6 60.8 21.9 45.4 187.5 20.5 86.6 67.6 1.7 0.2 0.0 0.4 0.1 0.2 0.7 1.6 0.4 0.6 0.3 0.4 0.3 1.1 0.3 0.1 0.7 6.2 0.4 0.7 1.0 0.6 1.3 0.7 0.9 0.7 0.8 0.8 0.6 1.2 0.8 1.1 3.2 0.5 1.6 5.5 6.2 3.9 5.8 5.2 1.7 3.9 6.0 4.6 32.9 4.1 7.3 0.0 17.3 6.0 4.5 3.9 3.4 7.8 5.5 8.0 3.5 1.8 34.5 3.3 1.1 35.6 5.3 6.1 9.9 0.0 21.1 3.6 1.2 11.1 0.0 2.5 9.2 2.0 0.0 5.2 3.1 1.5 3.2 0.0 2.8 3.2 2.8 3.1 1.5 1.6 2.9 3.9 1.2 17.7 3.1 8.0 9.4 2.5 1.7 0.0 3.1 7.8 48.9 49.8 9.5 4.8 7.8 5.1 4.8 16.7 3.0 CHGB "SCG1, SgI" ENSG00000089199 "Chromogranin B" P05060 20 5911510-5925353 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 13 "adrenal gland: 3466.0;pituitary gland: 1425.3" "Cell type enriched" "Detected in many" 5 "Enteroendocrine cells: 1036.1" "Cancer enriched" "Detected in many" 6 "pancreatic cancer: 154.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 23 "SCLC-21H: 355.0;SH-SY5Y: 541.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008759, CAB009403, HPA012602" Enhanced Supported Enhanced Vesicles "Intracellular and membrane" NA NA 6500000 "Cluster 20: T-cells - T-cell receptor" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 17: Intestinal endocrine cells - Hormone signaling" Vesicles "CAB009403: AB_2081255, HPA008759: AB_1846704, HPA012602: AB_1846706" "unprognostic (1.79e-3)" "unprognostic (7.72e-2)" "unprognostic (3.48e-1)" "unprognostic (2.90e-2)" "unprognostic (1.68e-2)" "prognostic unfavorable (1.89e-4)" "unprognostic (7.96e-3)" "unprognostic (2.86e-1)" "unprognostic (6.18e-3)" "unprognostic (7.93e-2)" "prognostic favorable (9.96e-4)" "unprognostic (8.56e-2)" "unprognostic (8.21e-2)" "unprognostic (1.56e-1)" "unprognostic (2.81e-2)" "unprognostic (2.73e-1)" "unprognostic (1.01e-2)" 27.5 3466.0 17.1 5.3 9.9 0.8 2.1 134.2 90.9 0.6 0.0 7.9 60.2 1.6 4.2 0.6 13.7 0.4 71.9 101.9 92.2 8.3 0.7 2.4 3.1 76.5 100.2 25.8 92.8 6.4 1425.3 0.7 188.4 5.3 14.2 56.9 6.1 3.8 11.0 1.7 31.6 0.9 12.8 0.3 133.3 14.9 19.3 4.0 9.7 0.8 1.4 0.4 2.3 14.2 0.0 7.9 0.9 0.0 0.2 0.2 0.4 0.2 0.0 0.1 0.0 1.9 0.0 0.0 4.3 0.0 4.9 0.1 0.0 0.1 0.1 0.6 0.1 2.6 0.0 1.6 0.1 4.2 0.2 1.5 0.0 0.0 2.1 0.1 0.1 0.2 0.4 0.1 1.0 0.0 0.1 0.9 19.7 1.3 0.0 0.1 0.0 0.4 0.5 0.2 355.0 541.8 0.0 0.5 0.4 2.1 0.3 0.4 0.3 0.1 6.4 0.4 3.3 0.0 0.7 2.7 0.5 3.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 17.1 9.9 134.2 90.9 101.9 92.2 76.5 100.2 188.4 12.8 19.3 14.2 0.0 3.2 2.4 7.5 0.3 4.2 9.9 0.8 0.0 93.3 0.1 0.3 114.4 0.0 0.7 69.9 20.9 0.1 0.0 1.6 1.9 0.5 7.1 0.2 0.7 3.0 1036.1 0.0 31.6 0.4 0.0 18.9 4.1 0.3 0.0 202.8 0.0 0.3 0.1 75.7 28.8 61.9 65.1 0.3 9.5 8.3 0.9 1.6 7.2 9.4 1.1 13.7 1.0 7.5 5.2 22.9 17.7 0.4 0.0 3.3 3.2 0.3 4.4 75.6 13.1 3.0 1.6 76.6 41.8 0.0 3.7 0.3 1.0 3.0 2.2 4.2 CHIC2 BTL ENSG00000109220 "Cysteine rich hydrophobic domain 2" Q9UKJ5 4 54009789-54064605 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 348.7;Suprabasal keratinocytes: 373.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Lineage enriched" "Detected in all" 4 "granulocytes: 365.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026782, HPA026784, HPA076603" Uncertain Enhanced "Vesicles,Plasma membrane" NA Yes "Cluster 38: Basophils - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 30: Epithelial cell lines - Translation" "Cluster 28: Keratinocytes - Keratinization" "Vesicles, Plasma membrane" "HPA026782: AB_1846654, HPA026784: AB_2732433, HPA076603: AB_2732317" "unprognostic (4.56e-2)" "unprognostic (2.24e-3)" "unprognostic (3.47e-3)" "unprognostic (9.58e-2)" "unprognostic (1.49e-1)" "unprognostic (2.25e-2)" "unprognostic (7.87e-2)" "unprognostic (1.22e-1)" "unprognostic (3.65e-2)" "unprognostic (7.81e-3)" "unprognostic (2.94e-2)" "unprognostic (5.63e-2)" "prognostic unfavorable (1.56e-4)" "unprognostic (2.89e-1)" "unprognostic (1.77e-1)" "unprognostic (4.56e-2)" "unprognostic (9.40e-2)" 20.8 15.9 9.1 12.9 8.5 27.1 18.1 12.6 9.6 16.0 12.1 12.4 12.3 12.3 10.3 27.4 12.1 20.5 15.1 8.6 9.2 14.2 20.3 19.7 14.7 8.6 8.5 13.0 9.9 6.5 9.3 13.5 9.0 12.9 8.9 5.9 15.2 5.7 9.8 27.5 13.2 10.5 7.8 17.3 12.9 39.6 9.2 21.9 11.9 6.6 13.3 15.1 18.1 9.7 25.4 4.6 12.8 11.9 21.5 16.8 13.1 34.6 36.1 20.1 20.3 18.1 22.0 21.4 29.5 22.0 17.2 7.7 17.9 25.1 22.0 11.9 9.5 11.7 4.2 13.6 65.1 19.2 23.4 22.6 19.8 30.3 45.3 38.3 30.0 22.2 13.0 15.4 40.6 7.1 22.3 30.7 8.7 11.2 16.9 14.3 7.3 8.4 23.3 8.1 19.7 18.3 8.3 12.2 26.6 18.3 6.1 26.8 51.3 25.2 19.9 36.6 21.4 18.4 9.5 17.2 18.7 18.7 18.7 365.5 79.3 171.5 60.1 64.7 57.7 41.3 60.0 68.6 55.9 40.1 54.6 59.6 325.0 74.2 68.3 47.0 81.5 77.9 9.1 8.5 12.6 9.6 8.6 9.2 8.6 8.5 9.0 7.8 9.2 9.7 58.1 6.4 7.3 35.6 42.5 348.7 95.5 61.0 68.3 8.1 61.6 33.5 4.1 15.7 25.9 7.3 8.4 27.8 57.8 27.2 17.6 42.8 55.4 64.1 58.0 64.3 25.8 72.6 39.7 28.0 38.7 80.8 32.6 34.2 36.3 36.8 38.6 23.9 24.7 13.5 40.2 21.9 40.7 36.4 144.2 13.4 17.1 50.3 67.6 49.6 32.6 9.0 28.8 74.4 23.2 61.8 42.1 24.5 40.2 85.1 41.9 29.2 56.0 7.2 19.7 53.9 45.1 163.5 89.9 97.4 373.8 47.7 65.8 39.8 21.0 135.9 CKAP2 "FLJ10749, LB1, se20-10, TMAP" ENSG00000136108 "Cytoskeleton associated protein 2" Q8WWK9 13 52455429-52476628 "Predicted intracellular proteins" "Apoptosis, Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 67.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 122.9;Granulosa cells: 88.6;Spermatocytes: 151.7;Spermatogonia: 87.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA008410, HPA027821" Enhanced Enhanced "Microtubules,Mitotic spindle,Centrosome" Yes Yes "Cluster 6: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Microtubules, Mitotic spindle" Centrosome "HPA008410: AB_1846832, HPA027821: AB_10602208" "unprognostic (1.85e-1)" "unprognostic (2.09e-3)" "unprognostic (2.44e-2)" "unprognostic (4.07e-3)" "unprognostic (1.39e-2)" "unprognostic (5.03e-2)" "prognostic unfavorable (3.26e-5)" "unprognostic (3.38e-2)" "unprognostic (4.24e-2)" "unprognostic (1.69e-2)" "unprognostic (8.30e-2)" "unprognostic (6.60e-3)" "prognostic unfavorable (1.90e-5)" "unprognostic (2.01e-2)" "unprognostic (5.20e-2)" "unprognostic (5.97e-2)" "unprognostic (6.36e-2)" 6.0 6.4 3.7 10.0 3.8 67.8 5.7 10.8 5.3 3.2 1.3 8.9 12.1 5.1 4.4 10.4 3.5 4.1 6.0 3.2 4.1 5.1 4.0 5.3 19.4 4.8 3.8 3.2 1.5 4.3 4.5 10.6 5.2 5.6 9.5 7.7 4.6 4.2 2.9 13.9 9.5 8.5 3.3 9.4 5.4 32.5 3.7 33.7 6.3 3.4 20.2 7.2 5.0 3.1 77.6 40.0 155.7 76.4 19.7 19.5 39.6 124.7 70.7 137.4 87.2 59.7 92.3 142.5 19.3 89.2 65.7 86.2 107.6 61.7 188.8 103.0 90.4 129.8 42.6 41.4 8.6 129.7 50.4 14.5 24.6 64.5 83.3 41.2 84.0 62.0 55.3 58.1 152.8 36.0 91.2 64.8 92.2 116.6 42.4 86.2 88.6 62.6 42.1 40.9 47.6 62.4 68.9 49.0 37.1 78.7 54.4 61.7 56.7 38.7 60.9 62.0 124.1 33.4 56.3 173.9 27.3 67.3 105.7 86.0 14.1 22.0 10.3 21.0 9.3 25.3 15.7 12.8 15.8 33.0 12.0 10.4 4.3 5.8 28.7 32.8 33.6 10.0 3.7 3.8 10.8 5.3 3.2 4.1 4.8 3.8 5.2 3.3 3.7 3.1 6.7 6.4 2.8 5.2 41.2 15.0 4.5 32.8 22.2 13.1 11.2 13.2 10.8 2.8 11.4 1.8 6.2 44.3 30.9 7.5 9.8 4.9 41.3 19.4 16.1 12.7 7.2 122.9 10.3 6.0 38.1 12.1 10.7 10.1 16.5 88.6 17.5 5.5 31.8 1.7 12.4 13.6 20.3 24.5 13.7 51.7 7.5 18.5 0.0 6.5 22.9 12.9 5.2 3.5 2.0 2.6 4.6 17.0 30.8 3.7 6.3 9.4 3.7 6.6 6.6 7.6 12.1 151.7 87.5 41.3 15.3 10.0 27.1 29.6 17.9 3.9 CKAP2L "FLJ40629, radmis" ENSG00000169607 "Cytoskeleton associated protein 2 like" Q8IYA6 2 112736349-112764664 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 13.1;lymphoid tissue: 12.1;testis: 4.5" "Cell type enhanced" "Detected in many" "Erythroid cells: 25.2;Granulosa cells: 12.5;Spermatocytes: 33.0;Spermatogonia: 35.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA039407, HPA040057, HPA070737" Uncertain Supported "Microtubules,Mitotic spindle,Cytosol" Yes Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Microtubules, Mitotic spindle" Cytosol "HPA039407: AB_10794091, HPA040057: AB_10794871, HPA070737: AB_2686303" "unprognostic (2.29e-1)" "unprognostic (1.54e-1)" "unprognostic (4.69e-3)" "unprognostic (1.42e-3)" "unprognostic (1.69e-1)" "unprognostic (5.59e-2)" "unprognostic (5.75e-5)" "prognostic unfavorable (7.63e-4)" "unprognostic (2.49e-3)" "unprognostic (1.91e-1)" "unprognostic (9.57e-6)" "unprognostic (2.42e-1)" "unprognostic (0.00e+0)" "unprognostic (7.37e-2)" "unprognostic (1.24e-1)" "unprognostic (1.30e-1)" "unprognostic (4.49e-2)" 0.4 0.1 0.2 2.6 0.2 13.1 0.4 0.4 0.3 0.4 0.0 1.6 1.5 0.3 0.1 2.3 0.1 0.3 0.0 0.2 0.1 0.1 0.3 0.3 5.0 0.0 0.1 0.0 0.0 0.0 0.0 1.8 0.0 0.1 2.2 0.2 0.3 0.0 0.0 1.5 1.1 1.1 0.0 0.9 1.0 4.5 0.2 12.1 0.2 0.0 5.2 0.8 0.6 0.2 47.9 9.6 35.4 16.2 2.0 3.3 7.2 38.5 32.2 37.9 36.1 8.7 13.3 32.0 15.5 15.1 48.3 18.0 20.4 19.6 64.1 44.8 8.9 53.6 12.7 7.7 0.1 25.2 30.9 0.9 1.9 47.4 27.2 10.1 17.5 22.8 14.3 44.9 31.2 6.9 31.0 10.6 15.4 20.0 29.5 22.3 37.0 8.4 6.9 18.7 19.7 12.7 15.2 12.8 13.3 13.2 12.4 11.8 12.9 42.7 33.7 34.5 28.5 9.9 20.1 26.6 18.5 18.1 69.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.2 0.2 0.4 0.3 0.2 0.1 0.0 0.1 0.0 0.0 0.2 0.2 0.1 3.2 0.6 0.0 1.2 3.3 2.1 2.7 0.6 0.0 0.5 0.8 0.5 1.5 0.4 0.0 0.0 11.1 1.3 1.3 0.0 0.4 2.4 1.1 1.6 1.1 0.0 25.2 0.3 0.4 10.6 2.0 1.5 2.1 0.0 12.5 2.9 0.1 6.6 0.0 0.2 3.1 2.0 1.9 1.4 2.1 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.1 0.0 5.6 1.1 0.1 0.1 0.4 0.0 0.0 0.4 2.8 33.0 35.7 9.5 1.7 1.0 2.5 0.7 3.8 1.1 CKAP5 "ch-TOG, KIAA0097, TOG, TOGp" ENSG00000175216 "Cytoskeleton associated protein 5" Q14008 11 46743048-46846308 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 119.7;Spermatocytes: 107.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039377, HPA040375" Supported Approved "Nucleoli,Nucleoli rim,Plasma membrane,Centrosome" NA Yes 360000 "Cluster 27: Non-specific - Gene expression" "Cluster 21: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Centrosome" "Nucleoli, Nucleoli rim" "HPA039377: AB_10805477, HPA040375: AB_10794739" "unprognostic (8.00e-2)" "unprognostic (7.35e-2)" "unprognostic (2.35e-1)" "unprognostic (4.12e-2)" "unprognostic (1.91e-1)" "unprognostic (2.08e-2)" "prognostic unfavorable (1.03e-6)" "unprognostic (6.09e-2)" "unprognostic (1.12e-2)" "unprognostic (2.21e-2)" "unprognostic (4.30e-3)" "unprognostic (3.77e-2)" "unprognostic (2.03e-1)" "unprognostic (2.71e-1)" "unprognostic (1.12e-1)" "unprognostic (3.48e-1)" "unprognostic (4.69e-2)" 12.8 30.7 15.9 15.1 19.5 25.9 14.9 30.8 24.3 11.7 5.2 18.5 12.6 15.7 12.2 13.0 11.5 12.2 21.3 21.4 18.0 11.5 45.5 10.4 18.4 21.0 17.4 27.8 9.0 21.2 12.5 17.3 22.9 15.9 17.2 57.0 9.1 13.2 37.8 13.7 12.3 19.3 17.5 11.9 16.1 33.0 20.2 36.4 9.6 28.8 18.5 13.5 10.8 24.6 104.7 95.8 212.6 90.8 48.7 73.0 48.3 117.1 69.4 107.8 114.6 76.8 33.3 104.5 41.0 76.0 117.0 116.2 144.0 62.7 134.3 102.0 107.6 176.6 80.2 78.4 35.0 139.6 76.7 37.0 34.0 60.3 125.6 56.1 79.3 97.9 129.5 103.8 89.2 71.2 127.9 39.2 114.7 78.8 73.0 131.2 210.0 98.3 34.7 63.3 96.8 83.9 149.8 56.9 57.3 88.9 103.9 39.1 64.0 106.2 92.9 180.8 176.2 59.2 137.3 158.6 66.5 64.9 105.9 4.6 4.2 4.6 6.1 6.2 5.9 6.5 4.5 6.9 6.1 6.2 5.4 5.8 0.7 8.6 6.2 3.9 5.6 3.1 15.9 19.5 30.8 24.3 21.4 18.0 21.0 17.4 22.9 17.5 20.2 24.6 13.4 25.6 23.6 32.3 17.4 8.5 11.0 17.9 16.5 19.3 11.6 12.3 65.2 12.8 18.8 9.2 37.5 19.4 11.2 13.3 9.8 12.2 119.7 19.7 21.0 16.5 12.1 32.6 61.9 7.8 15.0 27.8 29.0 18.8 37.9 55.5 11.7 8.1 18.7 13.5 63.1 16.9 16.2 17.6 5.6 50.7 19.6 19.6 7.2 30.9 16.5 16.2 16.5 32.6 51.7 13.7 15.2 29.0 26.4 14.2 9.1 9.3 30.7 25.6 19.7 18.0 21.4 107.4 59.3 24.3 11.6 11.5 16.1 83.3 19.8 9.7 CLDN18 SFTPJ ENSG00000066405 "Claudin 18" P56856 3 137998735-138033655 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 50 "lung: 252.2;stomach 1: 724.9" "Group enriched" "Detected in some" 53 "Alveolar cells type 1: 1602.5;Alveolar cells type 2: 431.2;Gastric mucus-secreting cells: 1153.4;Pancreatic endocrine cells: 442.5" "Group enriched" "Detected in some" 11 "pancreatic cancer: 113.6;stomach cancer: 186.8" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 19 "OE19: 15.1" "Not detected" "Not detected" "Not detected" "Not detected" "CAB013010, CAB013243, HPA018446" Enhanced Approved "Cell Junctions" NA NA "Cluster 4: Stomach - Digestion" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Cell Junctions" "CAB013010: AB_2533382, CAB013243: AB_2533383, HPA018446: AB_2669866" "unprognostic (1.03e-1)" "unprognostic (1.49e-1)" "unprognostic (2.93e-1)" "unprognostic (1.04e-2)" "unprognostic (1.41e-1)" "unprognostic (8.51e-2)" "unprognostic (5.14e-4)" "unprognostic (2.00e-1)" "unprognostic (1.29e-1)" "unprognostic (2.60e-1)" "unprognostic (9.54e-2)" "unprognostic (1.38e-2)" "unprognostic (4.42e-5)" "unprognostic (1.66e-1)" "unprognostic (2.26e-1)" "unprognostic (8.26e-2)" "unprognostic (2.95e-1)" 0.3 0.3 0.3 0.4 0.4 0.1 0.2 1.0 0.5 0.4 2.2 0.7 1.5 0.2 0.5 0.6 0.5 3.3 9.7 0.3 0.2 0.2 0.1 252.2 0.0 0.9 0.9 0.5 0.8 0.0 0.5 0.3 0.5 0.2 0.2 0.7 0.3 0.4 0.1 1.1 0.8 0.1 0.7 0.5 724.9 1.3 0.5 0.1 0.1 0.0 0.7 0.2 0.3 0.2 0.1 0.0 0.2 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.4 0.0 0.2 0.1 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.7 0.2 0.1 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.1 0.5 15.1 0.1 0.3 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.2 0.4 0.3 0.1 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 1.0 0.5 0.3 0.2 0.9 0.9 0.5 0.7 0.5 0.2 0.0 1602.5 431.2 1.0 0.9 0.0 0.0 0.0 0.0 1.1 0.0 0.0 17.0 0.0 11.2 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.6 0.3 0.2 0.6 0.0 0.0 0.5 11.4 0.0 1.4 1153.4 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.7 0.0 2.0 0.0 1.9 0.0 0.1 0.0 0.0 0.2 442.5 0.0 0.0 1.3 0.0 0.0 0.1 0.7 1.3 0.0 0.9 0.1 15.3 11.9 0.0 0.0 0.0 1.3 0.0 0.0 0.1 CLSPN ENSG00000092853 Claspin Q9HAW4 1 35720218-35769978 "Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 11.3;lymphoid tissue: 7.9;retina: 6.8;testis: 5.7" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 101.0;Spermatocytes: 281.1;Spermatogonia: 263.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Region enriched" "Detected in some" 6 "basal ganglia: 7.8" "Low region specificity" "Detected in many" "HPA026305, HPA026312" Enhanced "Nucleoplasm,Golgi apparatus" Yes Yes "Cluster 17: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoplasm, Golgi apparatus" "HPA026305: AB_2671833, HPA026312: AB_2671837" "unprognostic (4.75e-2)" "unprognostic (1.01e-1)" "unprognostic (9.64e-3)" "unprognostic (3.54e-2)" "unprognostic (6.82e-2)" "unprognostic (1.62e-2)" "unprognostic (1.18e-6)" "unprognostic (3.99e-3)" "unprognostic (2.08e-3)" "unprognostic (1.63e-2)" "unprognostic (8.71e-6)" "unprognostic (3.23e-2)" "unprognostic (7.61e-6)" "prognostic favorable (4.92e-4)" "unprognostic (5.12e-1)" "unprognostic (1.73e-1)" "unprognostic (1.29e-1)" 0.5 0.2 0.7 3.2 0.6 11.3 0.5 0.6 1.4 0.2 0.4 1.4 1.0 0.4 0.7 0.9 0.2 0.3 0.1 1.3 0.3 0.2 0.5 0.4 4.9 0.4 0.4 0.1 0.1 0.2 0.0 1.5 0.6 0.2 2.0 6.8 0.2 0.1 0.6 1.2 1.0 0.9 0.2 1.3 0.9 5.7 0.6 7.9 0.2 0.0 5.2 0.6 0.4 0.9 22.0 17.5 37.8 19.9 2.6 4.8 14.1 43.6 12.0 31.0 41.3 27.9 19.6 45.7 13.9 11.8 22.7 21.4 37.1 14.9 48.1 31.6 16.8 64.5 38.1 12.6 0.1 54.0 36.8 1.0 0.6 53.8 3.7 3.7 16.9 27.1 44.2 30.8 30.3 14.1 56.9 13.1 36.0 14.9 12.2 36.0 57.0 13.8 6.4 35.3 14.0 16.2 37.7 11.6 7.4 25.6 10.0 21.1 12.5 44.6 33.8 27.6 49.3 11.1 29.1 47.1 14.1 37.4 37.0 1.1 0.3 0.3 0.3 0.2 0.1 0.1 0.2 0.2 0.2 0.3 0.1 0.2 1.0 0.5 0.2 0.2 0.3 0.3 0.7 0.6 0.6 1.4 1.3 0.3 0.4 0.4 0.6 0.2 0.6 0.9 2.6 0.0 0.5 0.3 6.5 5.6 5.7 4.4 1.2 9.4 2.9 3.8 1.4 2.8 2.7 0.0 12.5 19.7 4.6 12.8 0.0 1.6 7.9 1.0 3.6 3.6 1.2 55.6 1.6 0.6 41.1 5.2 4.6 3.3 1.3 12.0 2.2 0.4 16.9 1.7 1.5 9.4 2.0 3.0 8.2 6.1 2.5 5.8 3.6 0.0 9.1 9.4 4.1 0.0 0.6 1.4 9.5 0.4 32.5 1.8 0.4 0.2 0.0 101.0 6.6 5.3 8.7 281.1 263.3 5.8 2.0 10.4 7.2 1.2 12.0 3.9 CNOT1 "AD-005, CDC39, KIAA1007, NOT1, NOT1H" ENSG00000125107 "CCR4-NOT transcription complex subunit 1" A5YKK6 16 58519951-58629885 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "RNA-mediated gene silencing, Transcription, Transcription regulation, Translation regulation" "Developmental protein, Repressor" "Autism spectrum disorder, Disease variant, Holoprosencephaly, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046577, HPA049664" Approved Supported Cytosol NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA046577: AB_2679706, HPA049664: AB_2680844" "unprognostic (1.30e-2)" "unprognostic (6.86e-2)" "unprognostic (9.25e-3)" "unprognostic (1.66e-1)" "unprognostic (2.39e-2)" "unprognostic (7.11e-2)" "unprognostic (3.58e-2)" "unprognostic (2.19e-1)" "unprognostic (6.43e-2)" "unprognostic (6.99e-2)" "unprognostic (1.83e-2)" "unprognostic (6.63e-2)" "unprognostic (1.33e-3)" "unprognostic (2.31e-1)" "unprognostic (1.12e-1)" "unprognostic (5.53e-2)" "unprognostic (1.52e-1)" 29.8 35.2 8.4 46.9 10.7 45.6 36.3 17.4 11.5 34.7 33.5 60.1 55.0 31.8 27.6 73.1 38.9 28.3 26.3 8.6 9.4 39.8 36.0 33.3 58.1 11.5 10.5 39.2 41.1 59.7 21.2 35.1 11.3 31.2 57.3 32.4 38.8 30.6 52.4 43.1 52.3 33.7 8.9 42.9 42.1 108.2 10.6 76.4 42.4 44.1 69.5 49.1 38.6 15.2 128.8 148.2 110.0 88.1 52.1 66.2 127.6 99.6 85.8 111.4 82.0 167.6 75.3 194.0 47.4 75.8 65.5 122.3 177.9 101.0 149.2 72.5 98.8 150.4 121.8 193.7 70.8 235.8 162.4 64.0 67.5 129.7 151.5 66.9 87.7 107.2 181.0 55.3 76.4 52.0 182.6 61.2 114.4 84.9 127.2 229.0 189.5 122.7 62.4 180.0 90.9 58.6 336.0 113.5 56.0 100.5 67.9 121.3 100.9 81.3 80.0 62.2 88.7 124.7 138.2 390.3 85.5 99.4 76.9 18.3 12.1 13.4 13.8 15.6 18.2 14.7 12.9 14.0 14.6 13.8 12.1 12.6 18.6 15.4 22.5 7.3 15.4 11.5 8.4 10.7 17.4 11.5 8.6 9.4 11.5 10.5 11.3 8.9 10.6 15.2 44.4 16.0 42.9 33.0 57.8 47.4 32.6 42.9 25.6 28.2 33.9 27.9 23.8 37.1 45.2 23.9 29.2 33.7 86.3 64.5 9.8 29.8 107.7 57.6 48.0 31.3 36.1 45.0 31.7 47.0 29.9 30.7 35.2 78.2 32.2 45.9 23.9 42.3 35.7 40.4 35.6 54.2 24.4 51.5 39.5 38.6 24.8 46.4 19.6 42.2 50.0 20.0 34.0 42.3 54.9 42.5 34.9 32.4 59.8 43.6 60.1 22.9 51.6 24.3 32.9 38.7 30.4 136.6 64.3 56.0 47.0 37.9 52.1 27.9 64.5 61.2 COP1 "CFAP78, FAP78, FLJ10416, RFWD2, RNF200" ENSG00000143207 "COP1 E3 ubiquitin ligase" Q8NHY2 1 175944831-176207286 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 28.1;Extravillous trophoblasts: 33.5;Syncytiotrophoblasts: 31.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 15: RT4 - Unknown function" "Cluster 7: Non-specific - Mitochondria" "unprognostic (1.99e-1)" "unprognostic (3.76e-2)" "unprognostic (4.17e-2)" "prognostic unfavorable (3.96e-4)" "unprognostic (2.95e-2)" "unprognostic (4.33e-1)" "unprognostic (2.01e-2)" "unprognostic (1.10e-1)" "unprognostic (2.78e-2)" "unprognostic (3.52e-2)" "unprognostic (9.24e-2)" "unprognostic (1.67e-1)" "unprognostic (1.33e-2)" "unprognostic (6.68e-2)" "unprognostic (7.01e-2)" "unprognostic (1.59e-1)" "unprognostic (1.55e-1)" 14.2 9.5 5.9 12.0 7.1 16.8 12.7 11.4 9.1 12.1 8.4 18.1 13.8 11.8 9.8 14.2 9.4 9.5 9.8 8.5 5.9 12.4 16.6 12.5 15.7 4.6 5.0 8.7 13.2 10.5 8.0 11.2 5.0 10.1 16.7 8.6 13.1 8.5 13.6 17.5 13.9 11.0 5.7 16.7 13.7 15.6 6.1 14.9 10.6 7.4 16.8 14.7 11.9 8.8 35.3 17.5 22.1 13.8 23.0 22.6 56.1 21.7 22.0 17.7 18.6 30.0 28.1 59.4 25.8 20.9 18.9 32.3 16.9 27.0 17.7 23.7 17.0 22.6 19.4 28.0 18.9 49.2 33.0 16.8 28.9 17.6 19.8 17.9 26.6 21.7 43.9 24.9 24.8 42.5 27.0 28.2 47.4 55.8 2.0 26.1 20.4 40.2 26.8 93.7 22.6 41.6 27.8 44.9 35.9 37.4 32.1 69.1 40.4 19.4 16.1 28.3 23.4 35.3 62.7 49.8 19.1 26.7 26.9 8.5 3.0 12.0 1.9 3.7 1.4 1.7 2.0 1.4 2.1 1.5 2.7 2.0 14.1 0.6 3.4 1.1 1.7 1.0 5.9 7.1 11.4 9.1 8.5 5.9 4.6 5.0 5.0 5.7 6.1 8.8 15.8 22.4 14.5 0.0 4.4 0.0 0.0 0.0 0.0 0.0 15.4 10.9 0.0 0.0 3.1 9.2 0.0 28.1 12.2 0.0 21.5 14.8 0.0 17.9 14.6 7.2 0.0 0.0 0.0 22.7 33.5 7.4 0.0 20.1 7.6 18.1 0.0 0.0 22.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 0.0 0.0 10.3 0.0 0.0 0.0 0.0 21.8 0.0 0.0 3.1 0.0 0.0 22.1 4.4 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 31.3 6.7 13.8 0.0 0.0 CPSF2 "CPSF100, KIAA1367" ENSG00000165934 "Cleavage and polyadenylation specific factor 2" Q9P2I0 14 92121969-92172145 "Plasma proteins, Predicted intracellular proteins" "mRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024238 Supported Approved Nucleoplasm,Vesicles NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Vesicles "HPA024238: AB_1847200" "unprognostic (2.31e-1)" "unprognostic (9.80e-2)" "unprognostic (3.73e-2)" "unprognostic (1.77e-2)" "unprognostic (4.95e-2)" "unprognostic (2.14e-2)" "prognostic unfavorable (4.35e-7)" "unprognostic (1.34e-1)" "unprognostic (2.94e-1)" "unprognostic (1.78e-2)" "unprognostic (2.33e-2)" "unprognostic (6.68e-2)" "unprognostic (8.78e-3)" "unprognostic (2.44e-1)" "unprognostic (2.91e-1)" "unprognostic (8.75e-2)" "unprognostic (4.90e-2)" 14.8 14.5 7.3 24.9 9.7 11.5 11.8 9.3 10.1 13.7 13.0 16.1 14.7 15.0 15.0 18.3 11.7 15.0 13.1 6.8 8.9 13.6 19.7 14.7 21.0 9.5 9.2 12.6 14.9 18.2 10.7 16.7 10.6 15.6 16.8 13.9 13.6 14.1 27.1 11.1 14.4 17.8 8.5 18.6 17.4 26.0 8.5 27.3 18.3 25.6 24.8 16.6 12.3 12.2 48.1 46.9 47.0 48.6 23.9 21.1 69.5 60.7 59.0 55.1 54.3 41.4 64.9 51.3 38.9 65.1 37.2 69.2 65.2 55.2 79.2 83.3 22.4 75.4 46.1 39.5 70.5 76.3 60.6 34.7 46.2 52.5 93.8 36.5 52.2 54.5 68.8 62.9 62.1 69.6 88.3 26.8 53.3 76.8 42.3 86.0 72.7 45.9 37.5 67.1 51.7 34.7 71.7 39.9 51.1 41.9 82.9 47.4 56.3 43.9 27.7 33.4 52.4 37.6 66.2 103.0 53.0 58.9 69.7 16.6 12.9 9.3 7.8 11.7 10.4 7.6 6.9 8.4 11.3 4.0 6.1 8.6 4.4 11.1 9.8 7.3 12.1 9.5 7.3 9.7 9.3 10.1 6.8 8.9 9.5 9.2 10.6 8.5 8.5 12.2 14.2 28.9 31.8 23.2 22.9 10.3 15.2 15.1 15.9 12.7 13.4 9.5 27.1 10.0 25.5 7.3 29.2 24.0 19.8 14.6 13.7 18.0 28.2 24.3 30.0 22.9 13.8 33.0 13.6 24.0 22.7 20.0 17.3 16.8 30.4 26.2 20.7 27.2 24.8 11.8 17.5 17.3 12.2 32.9 8.8 11.2 19.0 31.1 3.6 19.7 41.2 16.9 27.8 18.6 27.9 23.8 14.0 23.0 35.4 29.9 12.5 16.3 34.1 22.7 32.9 19.6 23.2 61.7 41.3 27.2 12.8 25.3 22.8 26.6 18.2 20.2 CRY1 PHLL1 ENSG00000008405 "Cryptochrome circadian regulator 1" Q16526 12 106991364-107093549 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Biological rhythms, Sensory transduction, Transcription, Transcription regulation" "Photoreceptor protein, Receptor, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 108.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB018762 Approved Supported "Nucleoplasm,Nuclear membrane,Microtubules" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Nuclear membrane, Microtubules" "CAB018762: AB_2083970" "unprognostic (1.21e-3)" "unprognostic (4.74e-2)" "unprognostic (6.50e-2)" "unprognostic (9.03e-2)" "unprognostic (1.79e-1)" "unprognostic (2.84e-1)" "unprognostic (3.48e-2)" "unprognostic (3.61e-1)" "unprognostic (4.29e-3)" "unprognostic (1.34e-2)" "unprognostic (6.85e-3)" "unprognostic (2.06e-1)" "unprognostic (1.20e-1)" "unprognostic (1.82e-2)" "unprognostic (5.08e-1)" "unprognostic (1.85e-1)" "unprognostic (2.25e-1)" 13.3 12.4 8.5 7.6 9.8 12.4 11.2 16.2 10.9 11.1 16.7 12.6 11.5 14.2 6.4 11.0 16.4 16.7 11.7 8.4 9.0 13.7 13.6 19.3 5.8 9.8 10.1 9.0 13.5 8.8 8.4 12.1 9.9 11.3 8.6 21.3 9.0 11.5 10.9 9.0 12.7 16.8 9.7 8.7 16.2 37.3 9.9 19.0 17.0 11.0 6.7 15.6 8.6 12.5 17.3 16.9 20.6 23.0 14.6 9.1 36.9 17.9 19.1 36.0 24.2 19.9 10.1 0.0 11.1 16.7 22.7 11.6 26.8 9.3 39.6 17.3 16.6 16.9 15.3 13.8 18.6 17.3 14.2 8.6 9.6 26.4 24.9 17.8 30.5 31.4 19.3 14.6 22.7 12.1 39.2 19.7 25.1 16.5 24.6 34.5 52.3 6.1 25.3 20.2 37.1 19.2 33.6 22.1 10.9 20.0 15.6 9.6 13.5 20.9 22.2 14.6 16.2 26.6 26.6 7.8 10.2 16.3 17.5 12.0 3.2 5.8 12.8 4.7 16.1 1.9 9.6 8.2 4.3 1.9 8.9 8.8 1.4 6.4 8.9 2.8 13.5 5.7 8.5 9.8 16.2 10.9 8.4 9.0 9.8 10.1 9.9 9.7 9.9 12.5 16.3 16.0 16.2 20.5 9.7 69.2 47.9 4.3 55.2 16.8 30.4 14.7 11.1 11.5 6.1 11.0 20.9 8.3 29.1 12.7 17.6 11.4 12.8 27.3 19.3 20.1 19.6 11.2 22.4 16.3 13.4 24.5 45.9 33.2 5.1 6.2 12.1 20.2 6.3 26.9 38.4 9.7 6.1 7.3 21.0 4.8 11.5 8.8 16.0 13.1 16.3 22.8 19.6 35.2 32.8 21.5 7.0 17.3 15.3 29.7 7.7 16.1 18.7 13.7 6.6 24.3 19.2 108.0 32.4 24.3 59.5 15.1 29.7 5.7 6.8 27.0 CSE1L "CAS, CSE1, XPO2" ENSG00000124207 "Chromosome segregation 1 like" P55060 20 49046246-49096960 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 164.0;Spermatogonia: 121.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002140, HPA038059, HPA038060" Enhanced Enhanced Nucleoplasm,Cytosol No Yes 320000 "Cluster 44: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 39: CACO-2 - Unknown function" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "CAB002140: AB_563461, HPA038059: AB_2675811, HPA038060: AB_2675812" "unprognostic (4.01e-2)" "unprognostic (3.15e-2)" "unprognostic (5.63e-2)" "prognostic unfavorable (2.91e-5)" "unprognostic (4.86e-1)" "unprognostic (4.91e-2)" "prognostic unfavorable (2.42e-8)" "unprognostic (3.44e-2)" "unprognostic (1.45e-2)" "unprognostic (2.63e-2)" "unprognostic (2.72e-3)" "unprognostic (2.54e-2)" "prognostic unfavorable (1.89e-4)" "unprognostic (2.59e-1)" "unprognostic (4.84e-1)" "unprognostic (5.71e-1)" "prognostic unfavorable (6.91e-4)" 23.6 24.5 16.0 29.0 20.2 26.4 34.2 26.6 21.1 25.7 12.9 23.6 19.8 28.1 23.8 38.2 27.0 19.0 24.7 17.1 18.0 29.8 30.9 19.7 35.0 21.0 17.3 27.2 20.4 30.8 13.6 37.5 22.8 25.8 28.7 23.2 21.7 25.6 39.8 34.4 19.2 35.0 21.1 20.3 20.7 87.7 17.0 40.7 23.4 41.5 42.8 27.5 22.2 29.1 224.3 152.4 182.1 140.9 69.0 88.5 196.7 172.1 90.5 528.1 222.0 501.8 175.4 227.3 224.1 109.7 213.9 251.4 270.7 322.9 500.0 37.4 131.3 158.0 166.1 244.7 42.0 176.2 83.3 50.0 118.7 259.0 148.7 72.4 177.5 124.3 227.2 87.1 201.1 76.8 213.9 90.6 153.5 185.1 224.0 133.9 299.5 176.4 116.5 153.2 159.6 92.6 275.2 293.3 97.1 137.7 245.3 113.3 115.5 279.3 233.9 166.4 247.9 50.5 130.8 210.8 166.8 139.5 152.2 18.6 16.3 3.8 13.8 20.6 21.1 16.7 21.0 17.1 20.1 13.6 22.1 19.3 4.4 23.0 23.6 8.9 20.1 18.3 16.0 20.2 26.6 21.1 17.1 18.0 21.0 17.3 22.8 21.1 17.0 29.1 16.4 6.4 26.8 8.1 20.3 30.2 25.8 29.5 31.3 14.9 17.4 15.9 26.6 24.3 22.4 27.6 10.4 71.8 15.7 7.4 13.7 32.2 95.9 14.7 19.4 22.9 5.4 40.4 20.9 26.6 61.2 24.6 13.7 17.8 4.5 35.1 19.2 26.7 29.7 15.2 24.4 11.8 20.3 17.9 21.9 57.8 25.4 17.9 26.6 9.4 28.0 22.6 7.2 17.1 41.7 26.7 10.0 31.6 26.7 28.8 9.9 21.6 21.7 15.5 39.5 19.3 22.1 164.0 121.5 36.7 34.5 72.7 17.5 31.1 23.7 22.2 CSTF3 CstF-77 ENSG00000176102 "Cleavage stimulation factor subunit 3" Q12996 11 33077188-33162371 "Predicted intracellular proteins" "mRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039743, HPA040168" Enhanced Enhanced Nucleoplasm NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 68: Epididymis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA039743: AB_10795682, HPA040168: AB_10794025" "unprognostic (2.38e-1)" "unprognostic (1.46e-1)" "prognostic favorable (1.63e-4)" "unprognostic (3.77e-1)" "unprognostic (4.04e-2)" "unprognostic (4.35e-2)" "prognostic unfavorable (8.20e-6)" "unprognostic (1.47e-1)" "unprognostic (1.67e-2)" "unprognostic (6.42e-3)" "unprognostic (9.73e-2)" "unprognostic (2.41e-1)" "prognostic unfavorable (1.61e-5)" "unprognostic (4.64e-2)" "unprognostic (1.86e-2)" "unprognostic (1.15e-2)" "unprognostic (1.01e-3)" 13.8 21.2 28.5 20.8 30.9 12.7 19.5 34.7 39.8 24.2 30.5 20.3 19.1 19.8 61.1 26.7 21.2 14.9 17.1 30.0 32.4 28.9 34.6 21.3 26.6 26.3 26.8 25.9 21.1 18.2 57.6 19.1 27.4 30.4 20.0 31.9 20.6 15.0 16.9 26.1 20.2 13.7 26.1 25.5 18.6 32.9 31.1 23.8 29.8 11.8 21.5 22.0 24.7 32.9 45.8 43.3 82.8 56.4 22.0 38.7 59.8 44.2 28.5 48.5 66.2 31.7 34.9 49.3 31.2 28.5 32.4 58.5 73.8 42.9 77.5 52.7 128.3 50.6 109.1 58.2 24.9 66.5 30.9 28.2 30.6 37.6 36.7 39.1 64.4 39.2 67.9 34.2 66.4 32.3 66.8 35.7 40.3 34.6 54.0 52.2 80.5 39.7 54.6 58.2 61.4 34.9 50.9 29.9 37.6 52.7 54.4 44.1 39.5 40.3 49.7 64.5 59.7 32.3 46.8 41.9 47.4 68.9 40.2 4.6 4.8 7.0 5.8 6.9 6.8 6.5 7.2 5.8 7.7 5.0 7.5 7.9 1.9 6.9 8.3 5.7 9.1 3.7 28.5 30.9 34.7 39.8 30.0 32.4 26.3 26.8 27.4 26.1 31.1 32.9 12.8 19.2 18.7 38.5 19.0 18.9 50.6 50.1 10.2 33.3 22.3 19.9 21.8 17.2 43.5 58.8 6.2 63.0 12.7 15.1 62.6 24.3 37.6 31.4 20.7 21.2 31.8 34.9 75.2 16.9 32.0 23.1 15.3 18.9 14.5 29.0 11.0 57.3 28.4 13.5 59.1 30.0 77.3 22.0 21.1 10.3 29.8 17.0 28.4 42.2 28.1 35.7 14.4 62.4 56.9 20.8 18.6 29.7 14.0 33.0 20.6 47.0 68.0 25.2 26.3 26.1 25.4 77.3 57.6 19.1 19.5 33.8 18.3 25.3 29.6 55.6 DAZL "DAZH, DAZL1, DAZLA, MGC26406, SPGYLA" ENSG00000092345 "Deleted in azoospermia like" Q92904 3 16586792-16670306 "Predicted intracellular proteins" "Differentiation, Spermatogenesis, Translation regulation" "Developmental protein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 79 "testis: 79.6" "Cell type enhanced" "Detected in some" "Early spermatids: 64.1;Late spermatids: 41.2;Spermatocytes: 257.9;Spermatogonia: 143.1" "Cancer enriched" "Detected in single" 51 "testis cancer: 13.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "HAP1: 18.8" "HPA019777, HPA047113" Enhanced NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA019777: AB_1847495, HPA047113: AB_2679936" "unprognostic (5.61e-2)" "unprognostic (5.27e-3)" "unprognostic (2.80e-1)" "unprognostic (5.85e-2)" "unprognostic (2.32e-3)" "unprognostic (2.60e-2)" "unprognostic (6.34e-2)" "unprognostic (4.91e-2)" "unprognostic (9.69e-2)" "unprognostic (7.79e-2)" "unprognostic (2.04e-1)" "unprognostic (3.47e-1)" 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.4 79.6 0.0 0.0 0.0 0.1 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 64.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 41.2 3.4 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 257.9 143.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 DDIAS "C11orf82, FLJ25416, FLJ38838, noxin" ENSG00000165490 "DNA damage induced apoptosis suppressor" Q8IXT1 11 82899975-82958277 "Predicted intracellular proteins" "Apoptosis, Cell cycle, Growth arrest" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 7.9;testis: 10.8" "Cell type enhanced" "Detected in many" "Plasma cells: 8.2;Spermatocytes: 17.2;Spermatogonia: 18.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA038540, HPA038541" Approved Approved "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Cytosol" "HPA038540: AB_10672648, HPA038541: AB_2676071" "unprognostic (2.53e-1)" "unprognostic (2.27e-1)" "unprognostic (5.04e-3)" "unprognostic (1.25e-2)" "unprognostic (1.20e-1)" "unprognostic (5.32e-2)" "unprognostic (3.86e-6)" "unprognostic (4.65e-3)" "unprognostic (1.01e-3)" "unprognostic (8.24e-3)" "unprognostic (2.04e-4)" "unprognostic (4.72e-2)" "unprognostic (1.11e-16)" "unprognostic (7.17e-3)" "unprognostic (9.59e-2)" "unprognostic (1.89e-1)" "unprognostic (9.13e-2)" 0.9 0.4 0.6 3.3 0.9 7.9 2.1 0.9 1.0 0.7 0.4 1.8 1.6 1.2 1.0 2.9 0.5 0.7 0.5 0.8 0.4 0.4 1.2 3.4 4.4 0.8 0.8 0.5 0.9 0.1 0.1 1.9 0.7 0.5 2.2 0.5 0.8 0.4 1.0 2.2 1.5 1.8 0.5 2.9 0.9 10.8 0.8 5.3 0.4 0.9 6.2 3.5 0.9 1.8 13.6 22.6 21.0 15.2 1.9 3.1 15.3 25.4 10.5 26.8 31.0 22.4 16.2 16.1 36.1 5.7 21.6 24.7 36.0 15.5 36.8 30.7 19.7 23.1 10.6 9.1 0.2 28.6 19.7 0.7 1.4 33.8 15.6 2.3 12.8 20.5 23.9 27.0 23.9 19.6 27.0 23.2 25.1 36.5 24.4 20.0 40.5 20.6 5.7 23.3 15.6 21.5 15.2 15.6 5.7 20.2 16.5 11.7 6.0 26.7 35.9 71.1 30.4 15.4 44.3 56.4 8.4 20.2 26.3 0.7 10.3 4.1 0.5 7.9 0.2 1.1 0.3 0.7 4.5 1.7 0.6 0.4 5.5 2.2 8.5 1.4 0.5 3.2 0.6 0.9 0.9 1.0 0.8 0.4 0.8 0.8 0.7 0.5 0.8 1.8 0.3 0.0 0.0 0.0 4.3 0.0 0.6 0.0 1.8 0.0 1.1 1.1 0.9 1.5 0.0 0.0 0.0 2.7 1.0 0.6 0.0 0.9 4.2 1.0 0.6 0.8 0.0 6.5 0.6 0.6 5.5 0.8 1.1 1.2 0.0 2.5 0.7 0.7 2.5 0.0 0.3 0.7 0.0 6.4 0.0 1.9 0.3 3.5 0.0 1.9 4.5 0.0 4.1 0.5 0.6 0.5 0.1 0.7 8.2 0.7 0.3 0.3 0.0 0.0 0.0 0.8 1.1 17.2 18.2 5.4 0.0 0.3 1.5 0.5 1.6 0.9 DMC1 LIM15 ENSG00000100206 "DNA meiotic recombinase 1" Q14565 22 38518948-38570204 "Predicted intracellular proteins" "Cell cycle, Meiosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 12.3" "Group enriched" "Detected in many" 5 "Spermatocytes: 109.3;Spermatogonia: 36.0" "Cancer enhanced" "Detected in some" "testis cancer: 1.7" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HDLM-2: 25.5;hTEC/SVTERT24-B: 17.4;U-266/84: 21.4" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA001232, CAB015397" Enhanced Approved Nucleoplasm NA NA "Cluster 11: Basophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 44: HDLM-2 - Immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "CAB015397: AB_629406, HPA001232: AB_1078683" "unprognostic (1.29e-2)" "unprognostic (3.11e-3)" "unprognostic (4.48e-3)" "unprognostic (5.71e-2)" "unprognostic (6.43e-2)" "unprognostic (2.22e-1)" "unprognostic (8.22e-2)" "unprognostic (2.61e-2)" "unprognostic (4.23e-2)" "unprognostic (3.99e-3)" "unprognostic (7.40e-3)" "unprognostic (1.00e-2)" "unprognostic (2.16e-4)" "unprognostic (3.94e-1)" "unprognostic (2.79e-1)" "unprognostic (7.27e-2)" "unprognostic (2.99e-1)" 0.7 0.2 0.4 1.3 0.4 2.3 0.9 1.2 0.7 1.0 0.4 0.9 0.2 2.5 0.9 0.9 0.8 0.4 2.3 0.4 0.2 0.5 0.3 0.4 2.8 0.5 0.2 1.2 0.5 0.3 0.4 0.7 0.5 1.2 1.1 0.8 0.3 0.7 1.3 1.6 0.7 0.7 0.1 0.5 0.6 12.3 0.1 3.4 0.3 0.5 3.1 0.6 0.7 0.5 7.1 2.6 5.0 0.1 0.4 2.1 0.2 7.4 1.0 11.7 8.1 0.2 0.8 3.5 0.3 2.0 0.0 1.2 2.0 0.3 13.1 25.5 0.5 13.6 2.0 0.2 0.2 1.2 2.7 0.5 0.0 17.4 0.0 0.1 0.9 11.2 10.5 3.5 4.1 3.9 2.8 10.3 9.0 3.5 0.2 6.2 0.0 5.2 1.5 0.9 9.7 0.5 12.5 1.1 0.1 1.1 2.1 2.9 0.3 0.1 0.8 0.1 0.1 9.8 21.4 6.4 2.0 2.8 0.9 0.4 0.1 0.1 0.3 0.0 0.0 0.1 0.2 0.1 0.2 0.2 0.2 0.1 0.4 0.5 0.1 0.1 0.1 0.1 0.4 0.4 1.2 0.7 0.4 0.2 0.5 0.2 0.5 0.1 0.1 0.5 0.6 0.0 2.3 3.6 0.7 2.3 1.0 0.4 1.8 0.7 2.7 2.4 2.5 0.0 2.7 3.7 0.0 1.9 0.4 1.3 1.9 0.2 2.9 0.9 0.8 0.8 0.0 11.8 1.1 0.0 1.7 1.4 0.0 1.3 1.3 1.1 0.4 0.1 1.0 0.0 1.4 1.6 0.0 0.0 1.2 3.0 1.5 1.1 0.0 1.9 0.1 4.8 1.0 2.5 0.6 0.1 0.5 1.5 3.8 0.2 0.1 0.4 0.9 0.2 13.1 1.3 0.9 109.3 36.0 0.3 0.6 0.8 0.9 0.3 2.5 0.5 DMRTC2 ENSG00000142025 "DMRT like family C2" Q8IXT2 19 41844743-41852333 "Predicted intracellular proteins, Transcription factors" "Differentiation, Sexual differentiation, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 106 "testis: 40.9" "Cell type enriched" "Detected in some" 4 "Spermatocytes: 162.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045016 Uncertain NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA045016: AB_10960404" "unprognostic (6.80e-3)" "unprognostic (4.38e-2)" "unprognostic (5.36e-2)" "unprognostic (2.69e-1)" "unprognostic (1.02e-1)" 0.0 0.0 0.1 0.1 0.1 0.3 0.1 0.2 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.3 0.1 0.1 0.0 0.1 0.1 0.0 0.1 0.1 0.1 40.9 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.2 0.2 0.1 0.0 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.6 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.7 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 162.6 38.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 DNA2 "DNA2L, KIAA0083" ENSG00000138346 "DNA replication helicase/nuclease 2" P51530 10 68414064-68472121 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication" "DNA-binding, Endonuclease, Helicase, Hydrolase, Multifunctional enzyme, Nuclease" "Disease variant, Dwarfism, Mental retardation, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 8.1" "Cell type enhanced" "Detected in many" "Erythroid cells: 33.2;Excitatory neurons: 14.1;Inhibitory neurons: 15.5;Oligodendrocytes: 18.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "NK-cell: 1.8" "Lineage enriched" "Detected in single" 5 "NK-cells: 1.8" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA037487, HPA057526" Approved Supported Mitochondria No Yes "Cluster 15: NK-cells - Transcription" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Mitochondria "HPA037487: AB_10672493, HPA057526: AB_2683456" "unprognostic (1.79e-1)" "unprognostic (1.35e-1)" "unprognostic (4.37e-3)" "unprognostic (4.60e-3)" "unprognostic (1.53e-1)" "unprognostic (1.86e-2)" "unprognostic (4.50e-5)" "unprognostic (3.36e-2)" "unprognostic (4.70e-2)" "unprognostic (3.72e-2)" "unprognostic (1.30e-2)" "unprognostic (3.29e-4)" "unprognostic (1.09e-10)" "unprognostic (3.43e-2)" "unprognostic (1.98e-1)" "unprognostic (9.36e-2)" "unprognostic (1.23e-2)" 1.3 0.9 1.9 2.8 2.1 4.6 1.8 2.5 3.6 1.4 1.0 2.3 2.1 1.1 0.9 1.9 0.9 0.9 1.8 1.8 1.9 2.6 4.2 1.8 5.2 2.3 1.9 1.2 1.6 0.4 1.5 1.6 2.4 1.9 2.8 5.3 1.6 0.4 1.6 1.8 3.2 1.1 1.6 2.1 1.9 2.9 2.1 8.1 1.0 0.9 4.2 1.4 1.4 3.2 25.6 13.0 29.0 20.7 3.2 2.2 20.4 12.4 10.3 17.4 21.2 31.1 16.1 26.1 4.6 3.8 6.7 15.2 16.8 6.5 20.7 16.2 12.6 15.8 8.5 12.3 0.9 27.7 16.4 1.8 2.6 12.3 3.6 4.5 7.9 17.0 23.6 22.8 10.1 9.0 42.8 19.8 20.5 10.9 24.0 33.1 20.0 8.4 7.5 11.7 13.1 15.7 16.9 21.4 4.2 20.1 16.5 11.6 3.4 6.6 20.5 8.5 23.8 11.5 13.9 38.3 5.7 26.1 8.9 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.1 0.1 0.0 1.8 0.0 0.0 0.1 0.0 1.9 2.1 2.5 3.6 1.8 1.9 2.3 1.9 2.4 1.6 2.1 3.2 1.0 6.4 1.1 4.9 1.3 2.3 0.9 1.7 2.8 2.5 2.3 1.4 10.5 2.8 1.1 1.8 6.2 3.9 2.2 1.7 0.0 0.8 2.2 2.0 1.4 2.0 1.2 33.2 14.1 0.9 4.8 2.0 2.6 2.8 0.0 6.0 0.7 4.6 2.2 0.0 15.5 1.8 0.0 1.3 0.7 3.7 0.6 1.5 0.0 4.7 0.5 0.5 2.1 5.5 18.4 0.7 0.1 0.7 7.4 2.5 2.4 0.6 0.8 4.3 0.0 2.4 1.1 9.1 12.2 4.7 1.7 1.2 1.6 0.7 3.7 1.0 DNMT1 "CXXC9, DNMT, MCMT" ENSG00000130816 "DNA methyltransferase 1" P26358 19 10133342-10231286 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Chromatin regulator, DNA-binding, Methyltransferase, Repressor, Transferase" "Deafness, Disease variant, FDA approved drug targets, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 388.1;Spermatocytes: 229.6;Syncytiotrophoblasts: 323.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002694, CAB005876" Enhanced Supported Nucleoplasm NA Yes "Cluster 6: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "CAB005876: AB_731983, HPA002694: AB_1847810" "unprognostic (3.51e-1)" "unprognostic (1.20e-2)" "unprognostic (1.26e-2)" "unprognostic (1.40e-1)" "unprognostic (3.62e-1)" "unprognostic (7.59e-3)" "prognostic unfavorable (1.46e-4)" "unprognostic (2.90e-1)" "unprognostic (4.23e-3)" "unprognostic (1.10e-2)" "unprognostic (1.07e-1)" "unprognostic (1.11e-2)" "unprognostic (1.28e-3)" "unprognostic (7.81e-3)" "unprognostic (1.73e-1)" "unprognostic (8.11e-2)" "unprognostic (1.46e-1)" 7.1 3.9 0.9 16.9 2.9 23.1 7.0 11.7 3.1 9.1 0.0 6.9 6.6 7.3 3.1 7.7 6.5 6.2 4.8 2.1 6.6 3.0 3.9 7.8 26.2 3.8 4.5 5.6 3.6 4.3 4.5 26.0 5.7 4.5 6.8 7.5 5.6 4.6 5.3 7.9 7.9 8.8 0.3 8.1 6.3 12.4 3.3 20.6 6.3 5.0 24.9 7.3 6.4 10.6 77.0 40.6 49.5 45.8 24.6 24.0 138.8 52.4 43.9 77.5 74.9 50.6 40.8 138.3 33.8 30.0 38.6 46.6 68.4 44.2 68.4 57.5 100.9 181.5 39.5 27.1 9.6 91.5 73.4 11.5 9.3 68.5 24.1 18.4 39.9 37.6 75.0 82.8 63.3 37.6 109.2 50.4 87.5 38.3 76.6 117.1 67.9 77.2 21.5 49.3 64.5 41.5 58.2 26.2 16.5 33.6 28.9 42.2 31.8 111.3 42.2 73.0 84.4 49.6 69.5 166.8 35.0 68.5 87.1 20.3 21.2 5.9 29.8 22.0 25.1 14.2 22.8 20.4 19.3 20.0 25.5 20.5 4.6 42.6 13.8 31.9 21.9 12.6 0.9 2.9 11.7 3.1 2.1 6.6 3.8 4.5 5.7 0.3 3.3 10.6 36.4 6.4 26.5 12.7 38.0 29.6 20.7 26.8 21.1 86.7 32.6 29.6 14.6 7.2 28.2 22.0 56.3 388.1 54.4 29.0 13.7 26.0 46.1 48.1 42.0 38.9 15.7 109.6 17.6 14.3 73.2 33.6 33.6 60.3 37.2 43.6 25.0 14.8 76.8 65.6 22.6 25.5 38.7 31.4 47.8 50.8 28.0 57.9 14.2 15.0 52.5 32.2 123.6 14.6 20.1 21.1 11.3 28.6 73.4 16.3 4.5 9.3 42.8 50.2 13.1 22.6 32.8 229.6 145.3 41.6 22.4 323.7 70.4 38.7 43.1 16.6 DYNC2H1 "DHC1b, DHC2, DNCH2, DYH1B, hdhc11" ENSG00000187240 "Dynein cytoplasmic 2 heavy chain 1" Q8NCM8 11 103109410-103479863 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Developmental protein, Motor protein" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 173.7;Cone photoreceptor cells: 112.6;Endometrial ciliated cells: 124.0;Excitatory neurons: 164.7;Inhibitory neurons: 101.8;Respiratory ciliated cells: 171.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 21.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039015, HPA039016" Approved Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 30: Epithelial cell lines - Translation" "Cluster 49: Ciliated cells - Cilium organization" Mitochondria "Nucleoplasm, Cytosol" "HPA039015: AB_2676309, HPA039016: AB_10673410" "unprognostic (3.11e-1)" "unprognostic (2.60e-1)" "unprognostic (1.28e-2)" "unprognostic (1.54e-1)" "unprognostic (7.11e-2)" "unprognostic (2.08e-1)" "unprognostic (4.14e-3)" "unprognostic (2.07e-2)" "unprognostic (2.05e-1)" "unprognostic (4.10e-2)" "unprognostic (2.87e-2)" "unprognostic (7.13e-2)" "prognostic favorable (8.49e-5)" "unprognostic (3.75e-3)" "unprognostic (1.62e-1)" "unprognostic (3.88e-2)" "unprognostic (4.11e-3)" 4.2 3.0 5.0 1.2 5.2 0.3 3.5 5.6 10.2 5.1 14.6 3.2 1.6 4.6 3.7 1.6 6.5 3.2 2.0 4.1 6.1 3.7 0.8 2.8 0.9 8.3 8.9 5.6 2.9 6.7 6.8 1.4 6.3 2.6 0.7 10.5 2.6 2.5 0.8 2.8 2.1 2.3 5.5 1.9 2.2 7.9 6.7 1.8 4.6 1.5 0.7 3.3 3.0 5.9 1.3 2.7 7.0 3.3 9.5 21.2 0.4 4.0 6.4 6.5 7.0 1.6 1.5 0.0 5.5 8.0 3.1 5.5 5.5 7.7 5.3 0.0 4.6 1.2 4.8 0.2 9.3 2.2 1.3 13.6 2.8 14.9 16.9 10.3 2.7 1.4 0.2 0.0 8.6 5.4 0.7 0.7 1.9 0.0 7.7 0.0 5.9 0.1 7.5 0.9 4.6 3.6 6.5 1.7 3.1 1.7 6.8 1.5 6.4 7.9 3.3 7.7 3.0 0.0 0.0 0.1 2.3 6.7 2.4 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.7 0.0 0.0 0.0 0.0 5.0 5.2 5.6 10.2 4.1 6.1 8.3 8.9 6.3 5.5 6.7 5.9 12.7 0.0 13.1 173.7 2.3 6.6 13.4 17.3 9.6 25.9 8.2 9.7 10.1 4.3 18.0 27.6 112.6 0.3 2.1 0.2 1.9 7.0 26.1 124.0 43.7 11.1 17.3 1.3 164.7 3.4 0.5 32.0 5.6 7.5 3.8 15.4 9.3 0.8 2.5 32.0 101.8 1.0 4.1 0.8 5.8 11.1 20.8 3.1 8.8 45.0 0.9 16.5 1.0 86.0 72.6 10.5 2.9 18.4 3.3 4.9 0.9 16.9 171.0 85.1 19.7 40.8 18.5 90.6 11.6 5.0 5.5 0.5 5.0 23.5 1.7 5.9 DZIP3 "hRUL138, PPP1R66" ENSG00000198919 "DAZ interacting zinc finger protein 3" Q86Y13 3 108589705-108694840 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 327.4;Respiratory ciliated cells: 218.2;Spermatocytes: 351.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035066, HPA049232" Approved Approved Vesicles No No "Cluster 15: NK-cells - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "HPA035066: AB_10601549, HPA049232: AB_2680684" "unprognostic (1.14e-1)" "unprognostic (1.90e-1)" "unprognostic (7.68e-2)" "unprognostic (3.12e-2)" "unprognostic (2.15e-1)" "unprognostic (2.37e-2)" "unprognostic (3.33e-1)" "unprognostic (5.16e-2)" "unprognostic (2.74e-1)" "unprognostic (3.76e-2)" "unprognostic (2.59e-3)" "unprognostic (5.38e-2)" "prognostic favorable (3.65e-4)" "unprognostic (6.06e-2)" "unprognostic (2.78e-2)" "unprognostic (5.51e-3)" "unprognostic (3.81e-2)" 5.2 9.7 15.6 4.9 19.4 4.0 5.3 11.8 18.6 5.3 22.6 5.1 3.0 7.9 10.1 3.9 18.7 5.9 11.7 18.8 18.5 10.9 4.3 6.5 10.2 13.3 14.9 10.5 5.3 7.8 24.5 4.9 12.4 9.7 4.7 29.8 3.6 7.0 12.4 3.7 3.9 5.2 10.4 8.3 6.6 34.6 15.5 8.5 12.8 16.2 8.0 5.2 3.4 15.0 9.8 8.2 24.8 14.7 10.7 10.8 8.6 6.1 12.2 10.1 13.9 12.1 6.8 18.0 12.8 6.6 20.9 3.5 13.7 5.3 21.0 6.6 6.1 8.1 3.4 8.5 6.3 3.3 4.5 11.8 2.8 9.4 11.4 10.2 6.4 10.9 8.0 8.7 19.6 8.6 8.2 3.5 15.5 5.0 6.2 10.4 20.5 1.8 8.4 4.7 17.0 16.2 9.8 1.0 11.1 21.6 15.1 2.8 7.6 9.0 13.7 1.8 5.3 9.6 6.0 34.7 6.8 2.7 11.3 6.5 0.5 1.2 4.1 0.8 5.0 6.3 4.2 5.1 0.5 4.6 3.6 4.8 0.1 10.6 1.5 1.5 6.0 1.5 15.6 19.4 11.8 18.6 18.8 18.5 13.3 14.9 12.4 10.4 15.5 15.0 7.3 12.8 12.8 86.8 14.8 7.5 8.6 16.3 9.1 67.8 9.6 8.3 45.0 4.3 26.6 33.1 327.4 21.9 17.1 4.1 13.7 12.9 28.4 106.1 16.0 8.7 52.8 11.1 145.2 9.0 8.8 18.2 9.2 9.2 8.8 30.9 7.5 4.4 9.4 77.4 103.4 6.9 34.6 5.7 7.5 59.9 17.4 5.7 7.2 37.5 10.5 32.9 11.3 79.4 80.6 8.9 4.6 17.7 9.0 6.9 4.5 20.6 218.2 33.7 19.7 16.6 17.7 351.3 112.5 4.4 7.4 14.8 29.4 35.4 7.4 5.6 ECT2 ARHGEF31 ENSG00000114346 "Epithelial cell transforming 2" Q9H8V3 3 172750682-172821474 "Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Neurogenesis, Protein transport, Transport" "Guanine-nucleotide releasing factor" Oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 64.6;Spermatocytes: 42.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA036363, HPA053261" Enhanced Nucleoplasm,Cytosol No Yes "Cluster 1: Neutrophils - Mixed function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "HPA036363: AB_2732472, HPA053261: AB_2682094" "unprognostic (3.83e-2)" "unprognostic (4.34e-1)" "unprognostic (1.27e-2)" "unprognostic (4.22e-3)" "unprognostic (4.49e-2)" "unprognostic (5.02e-3)" "prognostic unfavorable (6.82e-6)" "prognostic unfavorable (1.13e-4)" "unprognostic (1.82e-2)" "unprognostic (1.01e-1)" "prognostic unfavorable (2.24e-5)" "unprognostic (2.44e-2)" "prognostic unfavorable (1.19e-5)" "unprognostic (1.08e-2)" "unprognostic (1.46e-1)" "unprognostic (1.29e-1)" "unprognostic (1.33e-1)" 3.6 3.3 2.1 8.2 1.9 19.8 7.5 3.4 3.4 8.1 1.4 11.5 9.3 4.4 1.8 8.9 3.3 5.3 3.2 2.4 1.4 4.3 2.6 5.2 10.5 2.1 1.7 1.3 2.9 3.6 1.2 8.8 2.7 3.2 15.8 12.5 5.6 2.6 2.1 7.1 7.6 7.5 0.7 4.3 9.4 15.9 2.3 23.3 3.9 2.7 11.4 6.9 4.2 3.5 192.0 133.6 103.2 54.0 10.6 21.8 51.6 81.5 67.5 121.4 116.9 74.7 196.9 47.2 122.1 48.8 116.0 81.8 84.2 53.1 164.3 67.8 46.6 29.6 70.0 38.5 4.6 46.2 32.8 7.1 9.0 72.2 73.2 34.0 53.0 68.6 31.3 67.2 97.2 67.6 47.5 34.6 84.4 156.7 72.0 33.7 101.1 60.7 92.2 43.7 68.6 44.1 104.5 117.4 42.2 51.5 195.4 34.1 46.5 58.5 55.7 79.6 174.9 32.8 47.2 88.2 51.6 39.7 78.0 6.0 2.0 0.7 1.0 1.7 1.1 1.4 1.4 0.9 1.6 1.3 0.6 0.9 6.3 0.7 0.7 1.6 2.5 0.7 2.1 1.9 3.4 3.4 2.4 1.4 2.1 1.7 2.7 0.7 2.3 3.5 6.7 6.4 3.2 4.2 3.8 19.5 4.9 6.2 9.1 3.4 10.1 6.5 3.6 5.7 5.7 3.7 64.6 12.0 2.9 10.7 0.0 9.5 3.3 20.1 6.6 7.7 4.8 25.2 6.5 9.2 14.9 6.0 17.9 20.5 0.0 17.9 5.3 2.9 7.3 0.0 2.5 13.5 10.2 4.7 6.3 2.8 0.9 5.1 7.2 15.0 2.8 3.1 2.1 3.0 4.9 20.7 3.8 1.5 9.6 12.8 1.5 3.7 11.0 16.3 0.0 2.9 5.2 42.6 30.4 16.9 12.8 3.8 4.1 3.3 13.5 8.8 EIF2S1 "EIF-2alpha, EIF2, EIF2A" ENSG00000134001 "Eukaryotic translation initiation factor 2 subunit alpha" P05198 14 67360328-67386516 "Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis, Translation regulation" "Initiation factor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011663, HPA064885" Supported Enhanced Cytosol NA NA 210000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "CAB011663: AB_2096478, HPA064885: AB_2685382" "unprognostic (1.86e-2)" "unprognostic (8.33e-2)" "unprognostic (4.31e-2)" "unprognostic (2.46e-2)" "unprognostic (3.78e-2)" "unprognostic (1.78e-3)" "prognostic unfavorable (4.73e-7)" "unprognostic (4.14e-3)" "unprognostic (4.49e-1)" "unprognostic (1.68e-2)" "prognostic unfavorable (4.97e-4)" "unprognostic (2.95e-1)" "unprognostic (1.21e-2)" "unprognostic (1.73e-1)" "unprognostic (4.65e-1)" "unprognostic (1.59e-2)" "prognostic unfavorable (7.11e-4)" 28.3 24.5 12.5 29.9 14.0 25.0 25.7 15.1 17.8 18.1 10.4 25.0 21.5 19.4 19.6 38.8 15.8 21.5 28.7 14.6 14.1 24.5 35.3 18.4 30.4 13.7 12.7 17.1 26.3 22.9 9.4 26.3 13.6 22.1 26.7 21.2 18.3 22.3 49.4 23.7 21.5 27.0 13.8 19.8 19.8 33.4 13.5 27.9 27.9 40.6 33.5 39.1 19.0 16.6 265.7 86.4 59.8 92.3 56.4 63.4 127.8 115.5 68.3 127.4 110.7 101.6 92.2 118.7 57.0 87.4 85.7 100.4 139.1 110.3 192.7 86.9 51.9 76.9 80.0 70.4 59.2 82.7 71.9 52.4 62.6 113.9 172.5 49.8 105.4 73.8 132.6 89.6 127.3 131.3 113.7 64.7 61.1 157.9 142.9 85.7 99.0 84.6 78.2 120.0 85.9 60.7 83.0 96.5 91.1 52.3 164.5 70.8 81.3 167.4 180.7 82.0 124.4 77.0 90.4 180.7 97.1 145.3 110.2 51.4 50.6 33.0 47.4 71.0 58.4 55.4 54.5 51.7 70.1 45.8 50.3 51.5 6.9 58.6 62.8 48.0 64.3 70.7 12.5 14.0 15.1 17.8 14.6 14.1 13.7 12.7 13.6 13.8 13.5 16.6 64.1 28.9 40.2 17.3 44.1 142.8 88.2 77.2 37.5 22.1 32.0 30.1 92.8 30.0 55.8 22.0 12.5 78.7 38.0 23.3 70.5 89.6 81.0 34.6 48.9 60.3 13.1 64.2 21.7 63.0 104.7 51.2 34.1 44.8 35.5 35.7 26.4 39.8 70.4 37.0 20.9 30.6 61.1 37.9 51.3 33.4 31.1 40.7 51.6 15.9 61.3 32.2 36.0 15.1 23.8 70.8 18.3 40.6 56.7 79.9 26.6 65.1 35.0 35.2 26.3 60.7 85.9 204.9 96.3 49.7 130.4 93.4 46.1 57.9 39.7 79.1 ERBIN "ERBB2IP, LAP2" ENSG00000112851 "Erbb2 interacting protein" Q96RT1 5 65926556-66082546 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 119.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 70.5;dendritic cells: 61.3;Endometrial ciliated cells: 62.3;Glandular and luminal cells: 101.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048606, HPA059863" Approved Supported "Nuclear speckles,Plasma membrane" NA NA 39000 "Cluster 38: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 7: Non-specific - Mitochondria" "Nuclear speckles, Plasma membrane" "HPA048606: AB_2680461, HPA059863: AB_2684146" "unprognostic (4.34e-1)" "unprognostic (5.56e-2)" "unprognostic (9.88e-2)" "unprognostic (2.15e-2)" "unprognostic (2.04e-1)" "unprognostic (4.23e-3)" "unprognostic (1.74e-1)" "unprognostic (1.01e-1)" "unprognostic (1.46e-2)" "unprognostic (6.52e-2)" "unprognostic (5.45e-3)" "unprognostic (7.98e-2)" "unprognostic (5.62e-3)" "unprognostic (7.21e-3)" "unprognostic (3.08e-1)" "unprognostic (6.86e-2)" "unprognostic (7.81e-2)" 15.7 14.5 65.2 29.5 109.6 30.0 24.7 64.2 67.6 23.2 19.0 27.8 24.5 22.6 27.0 20.1 20.0 28.4 16.9 56.2 91.6 29.5 33.3 21.5 40.6 91.3 88.0 20.0 18.8 22.6 8.3 16.4 106.0 26.4 26.3 28.1 21.8 20.2 19.8 32.8 44.1 19.7 64.4 31.4 40.3 27.5 86.6 48.7 29.9 20.7 39.0 28.5 13.0 119.1 97.8 32.2 41.5 49.6 30.0 36.0 31.5 61.5 62.6 85.3 94.3 31.5 113.8 82.2 58.8 95.3 67.2 31.7 26.5 45.1 149.4 36.3 12.0 28.3 41.3 24.7 39.5 22.0 26.3 39.4 29.2 47.2 67.5 50.0 32.1 37.1 29.4 54.6 58.1 33.5 59.0 25.1 10.1 9.7 9.5 53.7 33.0 45.8 49.9 65.6 20.0 18.7 65.0 21.7 46.4 30.9 38.4 53.8 29.8 48.3 85.9 29.8 80.8 47.2 31.7 69.8 31.6 35.9 28.1 13.1 4.1 5.5 5.2 5.8 4.8 4.7 3.9 4.6 3.5 3.7 4.5 4.8 9.2 3.9 5.1 2.2 3.8 2.8 65.2 109.6 64.2 67.6 56.2 91.6 91.3 88.0 106.0 64.4 86.6 119.1 53.0 70.5 57.5 0.0 13.2 0.0 0.0 0.0 0.0 0.0 39.4 24.8 0.0 0.0 31.6 53.3 0.0 6.5 61.3 0.0 11.7 26.7 0.0 62.3 50.0 26.1 0.0 0.0 0.0 24.9 11.2 16.2 0.0 101.9 27.8 47.8 0.0 0.0 40.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.4 0.0 0.0 5.7 0.0 0.0 0.0 0.0 50.3 0.0 0.0 13.3 0.0 0.0 41.7 24.0 0.0 0.0 0.0 17.1 0.0 0.0 0.0 0.0 8.9 20.0 51.4 0.0 0.0 ERI2 "EXOD1, KIAA1504, MGC16943, ZGRF5" ENSG00000196678 "ERI1 exoribonuclease family member 2" A8K979 16 20780193-20900349 "Predicted intracellular proteins" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 39.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 13.8" "Lineage enriched" "Detected in many" 5 "granulocytes: 13.8" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035384, HPA035385" Uncertain Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 1: K-562 - Erythropoiesis" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Golgi apparatus" "HPA035384: AB_10602316, HPA035385: AB_2674600" "unprognostic (1.25e-1)" "unprognostic (1.47e-1)" "unprognostic (2.01e-3)" "unprognostic (4.36e-2)" "unprognostic (8.64e-2)" "unprognostic (2.78e-1)" "unprognostic (1.49e-1)" "unprognostic (1.55e-1)" "unprognostic (5.99e-2)" "unprognostic (3.04e-2)" "unprognostic (2.07e-2)" "unprognostic (1.08e-1)" "unprognostic (2.56e-2)" "unprognostic (1.54e-1)" "unprognostic (2.45e-1)" "unprognostic (1.05e-2)" "unprognostic (9.28e-3)" 4.7 6.8 4.3 3.7 4.9 6.4 9.2 4.4 5.5 3.9 4.8 7.4 8.1 4.1 7.6 6.7 5.7 4.5 4.4 4.1 4.4 6.5 12.1 4.7 3.8 4.9 4.4 4.5 7.4 14.0 5.0 5.4 4.9 7.5 10.2 4.2 5.1 4.8 5.1 7.1 7.8 4.6 4.6 3.6 8.4 13.1 4.7 7.5 6.2 3.7 4.4 4.5 4.7 5.7 17.1 7.9 21.6 9.5 6.5 8.3 13.0 13.3 7.9 11.8 14.9 10.2 17.0 4.8 14.6 7.3 8.2 12.7 21.8 13.7 21.8 15.3 11.4 11.5 9.7 17.6 6.0 22.3 9.0 7.5 16.7 15.9 13.2 6.3 7.2 0.0 37.1 13.5 20.0 15.3 3.2 19.8 13.4 17.5 4.5 25.5 17.7 10.5 11.0 13.4 11.0 13.5 8.5 16.0 10.3 11.4 33.7 24.7 5.5 12.5 7.0 12.2 17.9 8.3 13.4 2.9 11.9 17.9 17.6 13.8 1.8 1.7 0.4 1.3 0.3 0.5 0.4 0.4 1.9 0.0 0.3 0.2 0.1 0.5 2.6 0.6 0.8 0.4 4.3 4.9 4.4 5.5 4.1 4.4 4.9 4.4 4.9 4.6 4.7 5.7 4.0 16.0 6.7 18.3 1.0 5.0 5.3 5.6 8.0 5.3 11.3 5.8 7.3 5.7 8.5 9.2 0.0 8.3 0.9 8.0 9.8 4.1 22.5 6.9 5.5 3.0 0.0 22.7 10.4 5.2 9.1 4.3 9.7 6.0 0.0 7.1 2.9 10.9 8.4 3.3 10.6 9.6 6.1 8.2 4.1 14.7 6.2 5.8 1.8 5.6 6.7 5.0 3.1 10.6 20.3 4.7 6.6 5.3 2.8 4.5 7.5 6.8 12.6 3.5 0.0 5.6 3.5 39.3 20.0 9.7 3.7 3.7 2.5 4.5 8.5 5.7 FAM160A1 FLJ43373 ENSG00000164142 "Family with sequence similarity 160 member A1" Q05DH4 4 151409176-151670503 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 32.3;skeletal muscle: 34.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 11.9;Excitatory neurons: 15.8;Oligodendrocyte precursor cells: 19.1;Suprabasal keratinocytes: 14.5" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 11 "cerebellum: 13.8" "Immune cell enriched" "Detected in single" 14 "plasmacytoid DC: 2.5" "Lineage enriched" "Detected in single" 14 "dendritic cells: 2.5" "Cell line enhanced" "Detected in many" "A-431: 8.6;HeLa: 10.0;hTERT-HME1: 9.2;SiHa: 8.9;SK-BR-3: 7.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" HPA046348 Enhanced Approved Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 20: HeLa - Mitochondria" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA046348: AB_10966145" "unprognostic (1.96e-1)" "unprognostic (3.40e-1)" "unprognostic (1.21e-3)" "unprognostic (2.37e-2)" "unprognostic (2.54e-2)" "unprognostic (1.38e-1)" "unprognostic (5.33e-2)" "unprognostic (4.55e-2)" "unprognostic (1.52e-1)" "unprognostic (7.21e-3)" "unprognostic (1.30e-3)" "unprognostic (2.39e-1)" "unprognostic (1.51e-12)" "unprognostic (2.41e-2)" "unprognostic (2.34e-1)" "unprognostic (2.21e-1)" "unprognostic (1.28e-1)" 0.6 1.3 0.8 0.3 0.7 1.8 4.4 13.8 1.2 3.2 32.3 3.3 1.9 1.6 4.0 7.8 2.7 0.9 3.4 1.2 0.0 3.4 0.7 1.9 0.2 0.6 0.6 2.4 10.2 8.3 1.3 0.5 0.8 2.2 3.4 6.7 4.7 1.5 34.5 13.4 2.0 1.1 0.3 0.5 2.5 3.4 0.4 1.5 6.8 16.5 2.3 2.2 3.4 0.2 8.6 0.7 0.0 0.2 0.0 0.1 2.9 0.3 1.4 0.8 0.2 3.6 3.0 0.0 0.8 0.3 2.6 7.4 2.1 6.1 0.9 0.0 3.3 0.0 10.0 0.9 0.0 0.0 0.2 0.2 7.0 0.0 9.2 2.4 0.2 0.7 0.0 0.0 0.5 1.2 0.0 0.0 2.8 2.8 0.8 0.0 2.0 0.2 5.1 5.5 1.2 0.4 8.9 7.8 0.2 2.2 3.3 0.0 0.0 0.4 3.7 0.2 1.4 0.0 0.0 0.0 1.8 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.8 0.7 13.8 1.2 1.2 0.0 0.6 0.6 0.8 0.3 0.4 0.2 0.1 3.2 2.0 1.3 0.0 11.9 6.6 2.9 10.8 0.1 2.7 1.9 1.8 0.0 5.2 0.0 0.0 0.3 0.5 5.9 0.0 1.6 3.3 5.9 0.6 0.4 0.0 0.0 15.8 1.8 0.6 0.6 6.1 10.8 1.3 0.3 0.0 0.5 0.3 8.4 2.4 2.3 0.0 0.0 2.1 1.5 0.0 0.6 0.0 1.0 0.0 2.5 0.0 19.1 1.3 1.9 0.3 0.0 1.4 7.9 2.2 0.7 1.3 4.7 0.0 1.0 0.4 6.1 5.8 11.6 14.5 1.6 0.2 0.3 1.8 8.6 FANCA "FA-H, FAA, FACA, FAH, FANCH" ENSG00000187741 "FA complementation group A" O15360 16 89737549-89816657 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair" "Cancer-related genes, Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 20.2;testis: 21.6" "Cell type enhanced" "Detected in many" "Spermatocytes: 44.1;Spermatogonia: 38.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA063236 Supported Nucleoplasm NA Yes "Cluster 8: Neutrophils - Inflammatory response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA063236: AB_2684966" "unprognostic (5.99e-2)" "unprognostic (5.68e-2)" "unprognostic (2.36e-1)" "unprognostic (5.12e-2)" "unprognostic (1.87e-1)" "unprognostic (7.11e-2)" "unprognostic (1.45e-4)" "unprognostic (9.21e-2)" "unprognostic (1.58e-2)" "unprognostic (2.05e-1)" "unprognostic (4.82e-3)" "unprognostic (8.48e-4)" "unprognostic (7.82e-10)" "unprognostic (3.67e-2)" "unprognostic (2.05e-1)" "unprognostic (2.94e-1)" "unprognostic (1.62e-1)" 1.4 1.9 1.7 6.7 1.9 20.2 1.9 2.4 3.3 2.1 1.5 5.5 5.2 1.2 0.8 6.6 2.0 1.2 1.6 1.8 1.2 2.9 6.1 3.4 12.5 1.4 1.1 1.4 1.9 1.4 1.9 4.1 1.5 1.7 6.2 1.0 2.1 0.6 0.7 5.2 5.6 2.1 1.1 6.7 3.6 21.6 1.5 8.1 1.7 0.6 13.5 2.2 2.7 1.9 23.2 34.8 40.8 35.7 2.6 5.2 31.2 28.2 15.3 46.5 19.5 30.6 37.3 56.2 12.9 9.8 15.5 34.7 27.7 21.1 48.8 13.4 46.5 16.6 49.1 63.4 1.7 17.1 17.5 1.7 2.2 37.8 12.0 6.6 14.9 28.0 40.9 16.9 24.6 53.6 34.6 73.7 26.5 31.5 21.3 61.4 32.8 10.3 11.8 21.5 36.3 19.7 41.9 12.3 5.4 23.3 22.4 30.4 11.1 37.0 38.9 20.9 30.0 15.1 19.0 56.3 17.5 37.8 36.1 2.5 7.4 9.9 4.2 8.5 3.0 7.0 2.4 3.7 6.2 4.6 0.6 2.6 9.4 8.2 9.2 0.4 9.2 4.2 1.7 1.9 2.4 3.3 1.8 1.2 1.4 1.1 1.5 1.1 1.5 1.9 1.5 0.0 1.1 0.7 9.6 3.4 1.6 2.6 0.0 8.1 3.0 2.0 2.9 0.0 3.5 16.5 10.4 16.0 12.3 5.1 1.9 2.0 5.9 2.8 3.5 2.1 1.8 20.8 10.0 1.6 9.9 3.3 9.2 3.4 2.5 19.0 5.3 4.7 8.8 3.3 5.7 8.1 2.0 4.1 3.1 4.1 1.5 6.8 0.0 1.0 3.0 1.1 21.6 3.0 1.7 1.9 1.7 0.0 21.1 1.3 6.6 10.4 6.4 7.7 0.0 2.7 3.5 44.1 38.5 3.8 1.8 25.3 9.3 6.8 11.4 2.6 FANCD2 "FA-D2, FACD, FAD, FANCD" ENSG00000144554 "FA complementation group D2" Q9BXW9 3 10026414-10101932 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" "Cancer-related genes, Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 17.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 25.2;Spermatocytes: 62.5;Spermatogonia: 30.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 120.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB016117, HPA063742" Approved Supported "Nucleoplasm,Nucleoli,Nuclear bodies,Cytosol" No No "Cluster 46: Basophils - DNA binding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 28: BEWO - Transcription regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nucleoli, Nuclear bodies, Cytosol" "CAB016117: AB_2278211, HPA063742: AB_2685110" "unprognostic (3.25e-2)" "unprognostic (1.09e-1)" "unprognostic (6.21e-2)" "unprognostic (1.12e-2)" "unprognostic (2.92e-1)" "unprognostic (3.36e-2)" "unprognostic (1.08e-5)" "unprognostic (2.96e-2)" "unprognostic (1.59e-3)" "prognostic unfavorable (5.00e-5)" "unprognostic (1.23e-2)" "unprognostic (9.14e-2)" "unprognostic (4.41e-10)" "unprognostic (9.11e-3)" "unprognostic (3.99e-1)" "unprognostic (7.76e-2)" "unprognostic (2.89e-2)" 1.1 0.7 2.7 7.7 2.1 17.8 3.4 1.6 5.3 1.5 1.1 4.0 3.2 2.0 0.7 2.5 2.6 2.0 0.5 3.4 1.6 0.9 1.1 1.9 12.2 3.9 1.4 3.6 0.8 0.8 0.5 4.7 3.0 1.9 6.4 3.1 4.9 1.0 4.8 4.5 4.0 2.0 2.4 6.4 3.5 11.8 2.3 9.8 1.9 0.4 13.0 2.3 1.3 5.1 24.1 25.4 46.5 13.2 2.4 3.5 120.7 22.0 9.8 31.3 25.4 18.8 23.0 46.7 9.8 7.0 25.1 20.2 48.8 16.7 31.0 22.6 33.0 63.6 39.6 17.9 0.4 48.1 37.9 1.2 2.6 34.1 18.4 4.2 18.4 39.3 39.6 51.6 23.1 27.2 40.6 17.9 56.1 18.1 17.6 43.4 37.7 32.5 10.3 26.7 13.0 25.3 26.4 20.1 8.3 33.5 31.0 29.4 10.6 24.6 28.4 15.1 31.5 21.7 46.4 77.2 14.1 47.7 43.2 2.7 0.6 1.9 0.6 0.5 0.6 2.4 0.9 0.5 0.4 3.2 1.1 0.9 1.5 1.0 1.4 1.8 1.5 0.5 2.7 2.1 1.6 5.3 3.4 1.6 3.9 1.4 3.0 2.4 2.3 5.1 0.7 0.0 0.5 0.7 12.5 4.6 3.5 2.9 2.8 3.1 4.5 2.7 2.0 1.5 1.9 1.8 10.4 12.7 5.6 3.1 0.0 1.9 5.9 2.6 1.5 2.1 1.2 25.2 3.0 3.5 15.2 2.6 2.0 3.4 1.3 11.8 3.3 1.5 5.7 0.0 2.6 3.2 6.1 3.8 7.0 8.0 2.1 3.7 3.6 1.9 4.9 0.6 1.0 1.5 2.4 1.8 3.6 1.5 8.1 2.2 0.5 0.7 2.0 5.6 19.7 2.6 2.1 62.5 30.2 4.1 2.7 7.0 5.2 1.6 7.6 3.1 FANCI "FLJ10719, KIAA1794" ENSG00000140525 "FA complementation group I" Q9NVI1 15 89243945-89317261 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, DNA damage, DNA repair" DNA-binding "Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 31.4;lymphoid tissue: 44.2;testis: 32.6" "Cell type enhanced" "Detected in many" "Erythroid cells: 48.6;Spermatocytes: 69.5;Spermatogonia: 60.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "basophil: 23.4" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA039972, HPA040379" Approved Enhanced Nucleoplasm NA NA "Cluster 38: Basophils - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA039972: AB_10673265, HPA040379: AB_2676951" "unprognostic (6.88e-2)" "unprognostic (1.37e-2)" "unprognostic (1.66e-1)" "unprognostic (2.50e-2)" "unprognostic (2.99e-1)" "unprognostic (2.64e-2)" "prognostic unfavorable (1.11e-4)" "unprognostic (6.82e-3)" "unprognostic (1.15e-2)" "unprognostic (4.59e-3)" "prognostic unfavorable (3.59e-4)" "unprognostic (1.04e-1)" "prognostic unfavorable (2.71e-13)" "unprognostic (2.40e-2)" "unprognostic (2.72e-1)" "unprognostic (1.27e-1)" "unprognostic (2.12e-1)" 3.2 2.1 1.6 13.0 1.3 31.4 6.0 3.8 2.5 3.3 0.0 10.5 6.0 4.7 1.1 8.1 3.4 3.0 1.7 1.7 0.7 1.7 2.9 3.4 23.9 1.2 0.9 3.8 3.0 3.0 0.6 11.3 1.7 3.6 12.4 5.4 2.8 2.0 0.8 8.0 7.3 6.9 0.6 6.0 6.7 32.6 1.3 44.2 2.0 0.8 26.6 5.4 3.7 1.7 108.2 122.4 127.8 86.1 10.8 16.0 78.5 101.4 58.3 123.6 150.5 96.8 95.4 198.8 53.4 33.8 79.3 143.9 196.8 69.0 116.2 127.8 123.5 197.2 176.7 45.8 1.7 146.0 96.3 8.6 6.8 87.1 44.4 17.6 51.7 120.2 139.2 142.3 83.5 61.5 150.9 49.6 101.1 70.3 44.5 130.6 187.1 84.6 28.5 196.8 93.9 80.8 105.2 73.3 46.7 85.7 81.2 64.8 35.4 103.2 103.8 94.9 155.8 93.3 209.5 151.9 38.5 125.7 104.7 23.4 2.3 3.0 4.7 3.0 2.8 3.5 4.7 6.5 2.2 3.6 3.3 5.6 3.1 5.1 4.3 4.1 11.8 3.1 1.6 1.3 3.8 2.5 1.7 0.7 1.2 0.9 1.7 0.6 1.3 1.7 2.6 3.2 1.5 3.6 3.8 4.2 2.6 4.0 0.6 2.4 2.9 2.7 3.9 0.0 3.3 1.8 0.0 17.0 3.9 4.2 0.0 2.0 7.9 5.0 3.7 3.0 1.2 48.6 7.0 2.9 18.3 3.9 5.6 4.5 2.5 14.9 6.8 0.8 8.1 1.7 5.8 5.9 0.0 3.0 3.8 7.9 3.4 4.8 1.8 1.9 3.3 11.6 1.0 9.0 6.9 2.5 1.2 1.5 13.9 2.0 1.3 1.0 6.3 1.9 6.6 3.6 4.0 69.5 60.2 9.2 2.4 12.4 8.1 2.5 9.1 2.8 FARP2 "FIR, FRG, KIAA0793, PLEKHC3" ENSG00000006607 "FERM, ARH/RhoGEF and pleckstrin domain protein 2" O94887 2 241356285-241494841 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 128.2;Oligodendrocytes: 114.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031226, HPA055592" Approved Approved Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 68: Oligodendrocytes - Mixed function" Cytosol "HPA031226: AB_10602808, HPA055592: AB_2682856" "unprognostic (3.07e-1)" "unprognostic (1.39e-1)" "unprognostic (3.75e-2)" "unprognostic (1.07e-2)" "unprognostic (2.51e-1)" "unprognostic (1.37e-2)" "unprognostic (1.60e-2)" "unprognostic (1.70e-1)" "unprognostic (1.83e-1)" "unprognostic (2.19e-1)" "unprognostic (1.71e-1)" "unprognostic (1.90e-1)" "unprognostic (9.11e-2)" "unprognostic (6.31e-2)" "unprognostic (6.78e-2)" "unprognostic (2.74e-1)" "unprognostic (1.73e-1)" 9.6 10.3 13.8 11.4 16.8 5.4 9.0 19.3 16.0 10.0 9.8 22.6 20.2 10.6 7.3 14.1 9.2 10.0 7.6 13.2 12.9 11.0 17.1 10.4 11.9 15.6 15.2 11.0 11.4 13.2 8.4 9.0 15.6 10.1 21.3 10.1 9.2 10.0 10.6 22.6 18.9 11.6 11.7 11.6 20.3 28.1 16.2 8.5 6.8 9.9 13.8 14.2 10.1 21.3 20.0 14.3 25.8 17.7 21.9 29.1 23.1 19.7 16.3 20.0 20.6 15.3 23.4 8.5 5.2 38.8 14.1 22.4 35.0 20.6 30.4 13.3 18.1 18.8 25.4 20.3 16.0 17.0 14.1 29.3 15.2 29.2 23.7 9.3 18.4 16.1 21.7 7.6 16.3 16.7 18.3 12.5 12.8 35.3 11.1 20.3 58.2 25.7 25.9 41.0 30.5 20.3 22.1 15.4 59.5 14.9 8.1 16.8 27.9 18.8 14.3 23.8 16.0 13.0 10.0 18.8 17.2 11.5 39.0 6.1 2.1 7.3 1.3 5.1 1.2 4.4 1.4 1.5 3.1 4.9 0.9 1.0 1.3 1.7 2.8 6.4 2.2 1.6 13.8 16.8 19.3 16.0 13.2 12.9 15.6 15.2 15.6 11.7 16.2 21.3 8.9 28.9 5.9 27.4 23.9 15.4 11.4 8.0 16.5 12.7 11.1 8.3 29.6 14.3 12.3 18.4 18.8 5.8 9.7 36.3 3.9 9.3 42.7 12.0 10.6 10.5 28.1 3.4 43.1 12.3 5.4 12.9 45.3 14.0 6.3 15.9 11.0 11.6 4.2 20.2 36.7 38.7 10.2 8.4 9.4 25.0 14.9 11.9 39.2 38.4 8.5 4.9 2.1 128.2 114.0 12.6 24.1 10.5 14.4 12.8 20.9 7.1 17.3 15.1 19.7 21.4 14.1 45.6 19.7 13.8 15.2 11.1 6.0 11.3 26.2 22.4 FBXL5 "FBL4, FBL5, FLR1" ENSG00000118564 "F-box and leucine rich repeat protein 5" Q9UKA1 4 15604381-15681679 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 252.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 407.0" "Group enriched" "Detected in all" 5 "dendritic cells: 108.2;granulocytes: 407.0;monocytes: 225.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002484 Approved NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA002484: " "unprognostic (1.53e-1)" "unprognostic (8.08e-2)" "unprognostic (6.34e-3)" "unprognostic (1.08e-3)" "unprognostic (1.03e-1)" "unprognostic (1.53e-1)" "unprognostic (2.18e-2)" "unprognostic (6.12e-2)" "unprognostic (1.45e-1)" "unprognostic (2.42e-2)" "unprognostic (3.70e-2)" "unprognostic (5.14e-2)" "prognostic favorable (6.18e-5)" "unprognostic (1.02e-1)" "unprognostic (2.21e-1)" "unprognostic (5.39e-3)" "unprognostic (6.18e-2)" 72.8 50.9 49.0 40.2 53.9 110.9 51.9 56.3 65.5 53.8 50.3 51.3 29.8 42.1 63.5 43.0 46.1 51.6 49.5 48.1 51.2 128.0 77.4 48.8 35.3 49.9 52.6 41.5 32.7 59.4 44.4 37.1 50.1 51.5 36.2 48.0 36.9 56.4 80.1 36.3 31.7 55.1 50.9 45.1 41.5 68.0 52.2 46.3 70.6 85.5 32.6 53.9 37.7 55.2 23.3 17.8 42.3 23.9 65.0 63.9 13.4 30.4 37.2 32.7 45.9 14.3 34.1 18.1 14.2 36.4 57.8 8.5 21.9 36.5 50.3 17.7 11.2 17.8 12.9 16.9 65.3 21.7 16.4 59.0 48.4 30.4 46.9 74.9 86.8 15.7 15.2 14.8 99.1 10.5 41.3 33.4 22.3 19.1 15.8 29.5 43.0 14.8 51.8 32.9 20.4 19.2 28.4 10.0 32.8 57.7 16.2 35.8 20.8 37.8 10.7 26.0 38.0 20.1 22.2 16.8 32.4 37.7 46.6 204.3 225.4 115.2 46.2 112.9 44.9 33.5 42.5 44.7 108.2 31.3 44.0 44.8 407.0 42.4 101.7 16.6 40.6 206.8 49.0 53.9 56.3 65.5 48.1 51.2 49.9 52.6 50.1 50.9 52.2 55.2 37.0 44.8 62.0 63.6 31.3 27.3 37.2 40.5 62.0 52.3 34.6 28.2 88.1 41.5 46.9 36.8 6.2 53.3 38.9 24.4 78.2 29.2 80.3 32.5 41.2 42.5 25.9 29.9 73.6 23.3 41.8 47.0 36.2 42.1 39.9 38.6 40.0 69.1 48.5 40.4 78.7 20.1 32.6 109.9 28.4 52.9 39.7 81.1 30.2 63.7 138.4 36.2 44.3 65.9 120.2 18.8 20.4 58.3 39.1 30.8 37.2 252.3 61.9 41.1 59.2 42.1 46.2 188.5 73.5 63.1 26.1 26.4 45.4 38.4 25.6 32.7 FBXO47 ENSG00000204952 "F-box protein 47" Q5MNV8 17 38936432-38967403 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 39 "testis: 3.9" "Cell type enriched" "Detected in some" 6 "Spermatocytes: 74.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA057438 Uncertain NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA057438: AB_2683441" "unprognostic (1.53e-1)" "unprognostic (2.98e-1)" "unprognostic (2.82e-1)" "unprognostic (3.92e-1)" "unprognostic (6.04e-2)" "unprognostic (2.59e-2)" "unprognostic (2.29e-2)" "unprognostic (6.85e-2)" "unprognostic (4.15e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 1.2 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 6.6 0.0 0.0 74.1 12.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 FEN1 "FEN-1, MF1, RAD2" ENSG00000168496 "Flap structure-specific endonuclease 1" P39748 11 61792911-61797238 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication" "Endonuclease, Exonuclease, Hydrolase, Nuclease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 46.0" "Cell type enhanced" "Detected in many" "Erythroid cells: 87.5;Extravillous trophoblasts: 70.9;Spermatocytes: 61.0;Spermatogonia: 62.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002262, HPA006748" Enhanced Enhanced Nucleoplasm,Nucleoli NA Yes 160000 "Cluster 44: Non-specific - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Nucleoli "CAB002262: AB_563729, HPA006748: AB_1848494" "unprognostic (1.82e-1)" "unprognostic (2.71e-2)" "unprognostic (3.76e-2)" "unprognostic (2.77e-1)" "unprognostic (1.26e-1)" "unprognostic (6.45e-2)" "prognostic unfavorable (3.39e-6)" "unprognostic (1.50e-2)" "unprognostic (9.82e-2)" "prognostic favorable (7.85e-4)" "unprognostic (2.82e-3)" "unprognostic (5.86e-2)" "prognostic unfavorable (5.73e-6)" "prognostic favorable (9.46e-4)" "unprognostic (1.10e-1)" "unprognostic (4.49e-3)" "unprognostic (4.04e-2)" 5.9 10.4 7.8 21.3 7.8 39.5 10.2 10.9 9.9 6.2 9.6 15.5 11.2 6.3 7.1 14.2 5.7 4.3 6.6 8.0 7.7 5.8 9.9 5.6 34.0 10.0 8.3 3.9 6.8 5.6 8.3 12.9 10.7 6.2 16.1 17.4 6.1 5.9 13.1 9.6 11.4 8.9 6.8 12.8 8.4 19.1 9.1 46.0 4.8 9.6 37.4 8.1 4.9 8.1 154.6 139.7 149.3 81.3 14.9 18.0 94.9 133.3 76.1 160.9 181.4 123.4 112.8 222.6 100.3 57.3 150.5 158.3 214.3 117.7 163.3 117.8 117.6 117.6 187.7 127.3 11.0 184.7 115.4 12.7 15.8 148.1 39.0 23.3 63.1 122.1 181.3 155.1 136.0 195.4 259.7 165.4 165.3 120.3 134.7 173.8 173.7 228.9 64.4 144.7 170.0 140.7 89.6 115.0 79.1 70.1 167.4 127.1 43.2 141.5 178.1 182.3 134.6 120.4 204.3 228.9 98.4 121.9 124.6 24.7 6.7 14.2 16.2 12.9 16.8 14.4 12.3 15.1 8.0 14.8 14.0 13.8 2.7 20.0 12.9 24.5 25.2 10.3 7.8 7.8 10.9 9.9 8.0 7.7 10.0 8.3 10.7 6.8 9.1 8.1 2.7 0.0 2.2 0.3 14.0 10.3 5.2 18.2 7.4 23.8 7.4 7.4 5.8 5.7 7.7 0.0 12.5 53.0 15.9 6.7 7.9 17.3 21.7 4.2 5.5 5.5 4.8 87.5 2.0 12.2 70.9 8.6 7.1 6.3 0.0 18.6 1.1 7.2 25.7 15.2 2.4 8.0 18.3 5.4 6.8 14.4 5.6 6.2 5.4 0.0 12.4 31.3 13.4 1.5 3.1 12.2 9.4 7.2 45.3 6.5 3.7 5.7 6.4 23.3 0.0 6.8 12.2 61.0 62.1 11.3 6.1 30.9 11.0 9.0 22.0 5.2 HFM1 "FLJ36760, FLJ39011, MER3, SEC63D1" ENSG00000162669 "Helicase for meiosis 1" A2PYH4 1 91260766-91404856 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Meiosis "Helicase, Hydrolase" "Disease variant, Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "pituitary gland: 9.3;testis: 13.8" "Cell type enhanced" "Detected in some" "Astrocytes: 50.9;Inhibitory neurons: 38.4;Oligodendrocyte precursor cells: 90.5;Spermatocytes: 58.9" "Cancer enhanced" "Detected in single" "testis cancer: 0.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 5.2;AN3-CA: 2.8;K-562: 3.0;SH-SY5Y: 2.1;U-266/70: 2.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA035036, HPA035557" Supported "Golgi apparatus,Vesicles" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Golgi apparatus, Vesicles" "HPA035036: AB_2797224, HPA035557: AB_10696507" "unprognostic (1.35e-2)" "unprognostic (9.39e-2)" "unprognostic (1.17e-1)" "unprognostic (2.83e-4)" "unprognostic (2.05e-2)" "unprognostic (1.52e-1)" "unprognostic (7.43e-3)" "unprognostic (1.79e-1)" "unprognostic (7.75e-2)" "unprognostic (7.97e-2)" "unprognostic (1.76e-4)" "unprognostic (2.81e-2)" "unprognostic (1.06e-2)" "unprognostic (2.89e-3)" "unprognostic (2.78e-2)" "unprognostic (1.77e-4)" "unprognostic (9.59e-2)" 0.4 0.3 1.0 0.1 1.0 0.2 0.4 5.1 1.0 0.9 0.0 0.5 0.3 2.3 1.1 0.1 0.8 0.2 0.6 0.7 1.6 0.7 0.1 0.2 0.1 1.7 1.6 3.9 0.7 0.1 9.3 0.5 1.1 0.6 0.3 4.5 0.5 1.1 1.5 0.1 0.2 0.9 1.1 0.4 0.2 13.8 1.6 0.1 1.6 1.1 0.2 0.4 0.3 1.3 0.0 0.1 5.2 2.8 0.0 0.1 0.0 0.3 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.0 0.6 0.0 0.0 0.1 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 3.0 0.0 0.0 0.0 0.3 0.1 1.6 0.0 0.0 0.2 1.0 0.0 0.0 0.0 1.7 2.1 0.0 0.0 0.7 1.4 0.0 0.5 0.0 0.0 0.5 0.5 0.1 2.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.0 5.1 1.0 0.7 1.6 1.7 1.6 1.1 1.1 1.6 1.3 0.2 0.0 1.1 50.9 0.0 0.0 0.0 0.0 0.6 3.9 0.1 0.3 3.1 0.0 0.0 0.0 6.2 0.5 0.0 0.0 0.0 0.4 17.8 0.2 1.9 0.4 0.0 2.5 17.6 0.2 0.2 0.6 0.0 0.0 0.0 5.9 0.0 0.0 0.1 0.0 38.4 0.0 0.0 0.0 0.0 5.0 4.1 0.0 0.0 10.3 0.0 2.4 0.0 90.5 9.5 0.1 0.0 2.2 0.0 0.1 0.0 0.0 0.0 6.2 0.0 2.0 1.4 58.9 15.6 0.0 0.0 0.0 0.0 1.8 0.0 0.0 HMGB2 HMG2 ENSG00000164104 "High mobility group box 2" P26583 4 173331376-173334432 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Chemotaxis, DNA recombination, Immunity, Inflammatory response, Innate immunity, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 12 "bone marrow: 2347.2;lymphoid tissue: 939.2" "Cell type enhanced" "Detected in all" "Erythroid cells: 1915.4;Extravillous trophoblasts: 872.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 798.0" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MOLT-4: 2454.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003506, CAB037206, HPA053314, HPA073663" Enhanced Supported Nucleoplasm,Nucleoli "Secreted to blood" NA Yes 1200000 "Cluster 46: Basophils - DNA binding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Nucleoli "CAB037206: AB_1079071, HPA003506: AB_1079070, HPA053314: AB_2682109, HPA073663: " "unprognostic (2.82e-1)" "unprognostic (8.52e-3)" "unprognostic (2.56e-1)" "unprognostic (8.37e-2)" "unprognostic (8.05e-2)" "unprognostic (1.21e-2)" "prognostic unfavorable (3.76e-5)" "unprognostic (2.12e-1)" "prognostic unfavorable (3.13e-4)" "unprognostic (4.41e-2)" "prognostic unfavorable (7.04e-4)" "unprognostic (9.65e-2)" "prognostic unfavorable (7.60e-12)" "unprognostic (1.60e-2)" "unprognostic (2.83e-2)" "unprognostic (2.68e-2)" "unprognostic (1.21e-2)" 90.3 31.0 36.3 146.1 38.4 2347.2 89.1 35.4 49.9 79.0 33.0 117.1 93.2 92.3 47.3 115.6 78.8 43.5 85.8 33.2 38.3 74.3 37.8 83.8 390.4 37.5 36.8 118.9 27.2 18.3 35.4 111.0 38.0 46.9 122.2 134.1 59.8 35.2 72.4 75.1 108.7 65.5 36.3 159.5 66.0 136.0 36.1 939.2 56.4 57.0 388.9 68.2 86.1 40.1 498.2 114.6 976.8 444.4 118.2 118.2 375.1 366.3 271.3 386.7 345.7 329.0 673.6 1645.5 79.2 203.0 207.4 190.3 645.0 196.1 601.0 1004.0 303.4 1823.2 308.8 487.8 115.7 1642.8 683.4 114.7 59.2 194.2 439.1 211.5 402.8 866.1 703.9 2282.4 358.9 409.9 2454.9 1513.7 355.4 289.4 199.3 1226.7 499.7 620.4 227.0 208.8 838.6 759.0 365.5 209.6 166.6 340.8 291.1 1173.2 236.0 175.5 513.6 219.0 554.9 734.8 437.1 1869.4 149.1 1178.4 464.4 798.0 135.9 407.0 94.1 57.6 86.2 72.5 137.8 131.1 112.8 57.6 88.4 85.3 316.7 83.0 49.1 43.2 266.4 107.6 36.3 38.4 35.4 49.9 33.2 38.3 37.5 36.8 38.0 36.3 36.1 40.1 167.0 28.9 64.1 5.9 153.2 158.8 141.5 131.8 75.1 48.9 75.3 107.8 229.0 38.6 78.3 55.2 35.5 472.6 222.9 116.5 142.8 25.9 30.4 71.2 71.7 128.0 74.7 1915.4 2.7 16.1 872.5 121.5 63.2 76.5 110.6 210.5 171.7 26.5 210.1 45.4 4.7 191.2 109.9 295.0 142.9 33.1 105.3 233.9 67.6 6.5 241.9 81.8 132.8 1.0 4.8 11.3 75.2 57.6 268.6 114.2 65.4 51.0 149.8 143.5 78.9 71.7 134.4 493.6 400.9 233.6 134.0 128.7 289.5 42.3 284.7 89.0 IFT46 "C11orf2, C11orf60, CFAP32, FLJ21827" ENSG00000118096 "Intraflagellar transport 46" Q9NQC8 11 118544528-118572970 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 64.9;Respiratory ciliated cells: 84.3;Spermatocytes: 44.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037909, HPA057550" Approved Approved "Actin filaments" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 49: Ciliated cells - Cilium organization" "Actin filaments" "HPA037909: AB_10672731, HPA057550: AB_2683464" "unprognostic (8.77e-2)" "unprognostic (1.22e-1)" "unprognostic (2.79e-1)" "unprognostic (2.35e-3)" "unprognostic (6.76e-2)" "unprognostic (1.55e-2)" "unprognostic (1.07e-1)" "unprognostic (3.29e-2)" "unprognostic (3.75e-3)" "unprognostic (1.47e-1)" "unprognostic (1.37e-1)" "unprognostic (3.61e-1)" "unprognostic (9.02e-3)" "unprognostic (1.42e-1)" "unprognostic (2.48e-1)" "unprognostic (6.53e-2)" "unprognostic (2.41e-1)" 14.7 19.4 29.0 8.8 29.7 5.6 26.8 33.9 35.8 23.1 37.3 18.6 7.7 19.4 24.8 13.7 66.8 16.4 21.3 28.5 32.5 26.9 17.0 15.1 11.0 32.1 37.2 27.2 16.7 18.4 28.9 8.7 31.8 20.9 11.1 35.7 15.9 20.2 17.9 13.5 10.3 20.7 31.5 11.8 15.0 28.1 31.4 16.0 27.5 17.6 12.8 16.0 16.7 32.1 15.6 18.4 26.1 16.9 42.8 35.7 3.2 31.9 46.2 29.3 27.6 22.5 28.8 23.8 46.1 38.6 7.2 22.1 26.7 31.8 34.4 9.1 21.8 49.2 9.0 8.6 32.0 11.8 13.8 32.4 37.0 49.0 46.2 26.6 28.9 32.1 27.4 16.0 37.3 71.7 31.3 15.6 7.7 27.3 38.0 25.6 20.0 19.0 23.5 21.4 16.7 18.3 23.2 29.9 20.1 15.0 46.2 16.7 24.6 31.6 20.2 18.4 12.0 9.9 14.3 26.7 16.0 21.2 23.2 2.8 5.2 5.9 8.6 4.3 9.9 11.1 7.6 7.9 6.9 8.3 9.2 5.5 1.6 11.0 4.2 7.0 9.9 4.8 29.0 29.7 33.9 35.8 28.5 32.5 32.1 37.2 31.8 31.5 31.4 32.1 5.5 9.6 10.3 10.4 4.9 4.0 8.3 14.4 8.0 12.5 11.6 8.4 14.5 10.0 15.4 11.0 18.8 5.3 3.8 1.6 5.9 17.1 20.5 64.9 11.7 9.3 4.2 6.6 8.7 11.6 7.1 9.5 4.1 9.6 12.0 10.2 8.6 5.9 8.8 1.7 8.9 4.3 14.2 2.4 3.5 15.7 10.2 3.1 1.8 5.6 5.5 14.8 2.1 4.0 6.4 10.2 4.2 18.4 6.1 6.1 3.4 14.3 84.3 16.5 0.0 11.3 11.5 44.9 38.4 6.5 7.0 1.9 4.2 9.8 5.3 3.9 ILF2 NF45 ENSG00000143621 "Interleukin enhancer binding factor 2" Q12905 1 153661788-153671028 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007484 Supported Supported Nucleoplasm No No 3400000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "HPA007484: AB_1079137" "unprognostic (1.97e-3)" "unprognostic (8.68e-2)" "unprognostic (3.44e-2)" "unprognostic (3.15e-2)" "unprognostic (8.75e-3)" "unprognostic (9.70e-2)" "prognostic unfavorable (5.71e-8)" "unprognostic (2.64e-1)" "unprognostic (4.66e-2)" "unprognostic (3.22e-3)" "unprognostic (1.94e-2)" "unprognostic (3.03e-1)" "prognostic unfavorable (5.57e-4)" "unprognostic (2.61e-1)" "unprognostic (4.17e-2)" "unprognostic (2.65e-1)" "unprognostic (2.09e-1)" 81.4 84.2 42.3 81.5 44.1 158.1 100.7 45.9 51.1 75.4 51.2 80.5 57.4 75.6 85.7 99.1 77.5 61.0 71.3 43.5 47.9 97.6 69.0 76.1 97.7 44.8 44.9 75.4 79.7 101.7 75.3 86.1 46.1 63.5 91.3 43.4 84.3 61.2 114.6 90.0 63.3 79.2 46.8 78.1 76.9 101.2 44.6 189.7 88.7 85.9 132.4 105.8 69.5 50.6 323.3 244.7 420.1 297.8 173.1 162.4 336.2 233.5 263.6 411.9 294.5 362.1 254.3 441.5 349.5 233.6 198.8 239.3 508.8 248.3 394.6 242.0 328.9 330.5 182.2 310.0 158.6 521.0 234.7 149.6 139.7 314.4 339.1 171.7 389.3 256.0 423.5 203.4 347.2 424.3 702.8 215.4 607.5 468.5 366.2 502.1 367.2 418.3 194.8 304.0 379.5 350.2 272.3 336.1 272.3 392.0 367.2 442.7 239.5 210.7 266.4 191.6 391.8 348.6 522.6 882.9 177.2 314.1 327.2 168.7 158.1 118.1 147.4 156.0 188.0 198.7 169.8 160.3 219.2 165.0 190.7 164.8 14.8 218.5 129.7 212.2 212.6 357.3 42.3 44.1 45.9 51.1 43.5 47.9 44.8 44.9 46.1 46.8 44.6 50.6 101.4 57.7 68.5 6.8 102.1 197.9 220.9 238.0 129.7 38.0 113.5 112.1 62.2 70.1 130.4 38.6 27.1 215.3 99.0 54.2 131.0 209.9 73.9 81.6 84.4 114.0 106.8 113.0 9.4 156.4 259.3 110.8 50.4 103.0 94.4 107.0 49.2 31.5 124.8 28.6 10.5 87.2 164.8 54.9 117.4 33.1 60.0 74.0 112.1 9.4 112.9 82.8 61.8 10.6 17.1 145.4 63.5 65.8 125.4 139.9 45.5 201.6 80.7 36.3 65.7 102.4 124.2 360.3 159.9 119.1 158.8 260.4 101.4 144.9 110.9 181.0 INTS8 "C8orf52, FLJ20530, INT8, MGC131633" ENSG00000164941 "Integrator complex subunit 8" Q75QN2 8 94813311-94881746 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057299 Approved Approved Nucleoplasm Yes No "Cluster 26: Non-specific - Mitochondria" "Cluster 23: Testis - Cell cycle regulation" "Cluster 21: OE19 - Mitochondria" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA057299: AB_2683403" "unprognostic (1.08e-2)" "unprognostic (3.12e-2)" "unprognostic (1.28e-1)" "unprognostic (5.86e-2)" "unprognostic (1.96e-1)" "unprognostic (4.81e-2)" "prognostic unfavorable (2.54e-6)" "unprognostic (3.07e-2)" "unprognostic (6.87e-2)" "unprognostic (9.77e-3)" "unprognostic (4.84e-2)" "unprognostic (1.53e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.24e-1)" "unprognostic (5.60e-2)" "unprognostic (1.11e-1)" "unprognostic (3.96e-2)" 8.8 7.5 4.4 13.9 4.8 15.5 8.1 8.3 6.4 14.5 6.9 12.8 7.8 13.2 4.2 10.5 9.5 7.3 10.2 4.8 6.4 6.4 8.9 7.5 17.4 5.7 4.4 11.4 13.5 10.1 8.3 9.4 4.6 10.4 14.8 10.3 11.0 8.7 12.6 10.3 10.6 13.6 4.0 9.9 10.6 30.6 6.3 20.6 8.8 12.0 13.6 10.4 10.4 6.1 52.4 31.9 49.2 43.4 17.7 41.7 25.5 27.5 26.0 35.7 33.0 22.5 38.0 52.3 25.2 20.7 44.3 31.5 61.3 29.2 47.6 58.1 28.8 45.7 19.3 22.1 21.1 24.6 31.7 17.1 13.5 34.7 29.6 40.8 40.1 35.1 44.4 38.9 22.0 34.5 53.7 20.4 28.1 114.9 55.8 42.7 19.7 29.0 30.0 26.6 34.6 18.4 26.8 7.7 24.1 40.3 37.3 31.6 28.1 16.1 18.9 31.1 25.1 22.0 43.0 45.2 21.6 49.4 32.2 2.1 9.6 15.1 4.6 6.8 7.5 13.4 10.8 11.8 9.3 10.4 11.0 6.5 9.3 9.6 6.6 5.5 10.0 4.5 4.4 4.8 8.3 6.4 4.8 6.4 5.7 4.4 4.6 4.0 6.3 6.1 11.0 16.0 8.6 16.6 19.4 5.9 11.6 9.1 9.6 13.7 6.1 4.6 8.3 5.7 11.6 7.3 33.3 10.0 9.7 10.3 3.9 8.3 36.0 15.0 12.1 11.8 18.0 17.7 44.8 13.4 12.9 10.8 8.6 6.1 12.7 15.2 8.9 5.5 9.5 28.6 40.9 11.8 8.2 11.6 6.6 6.4 16.1 14.0 7.2 25.3 21.6 8.0 16.5 33.2 31.2 10.9 14.6 16.1 18.0 8.8 9.5 5.1 19.7 18.9 6.6 10.6 13.1 54.7 32.5 9.0 7.0 8.5 14.2 11.0 11.1 8.1 IQCB1 "KIAA0036, NPHP5, SLSN5" ENSG00000173226 "IQ motif containing B1" Q15051 3 121769761-121835079 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" Calmodulin-binding "Ciliopathy, Leber congenital amaurosis, Nephronophthisis, Senior-Loken syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 155.3;Spermatogonia: 96.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 131.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042028 Approved Approved Supported "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 43: B-cells - Humoral immune response" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Microtubules, Cytokinetic bridge, Mitotic spindle" "HPA042028: AB_2677806" "unprognostic (3.82e-2)" "prognostic favorable (1.77e-4)" "unprognostic (2.16e-1)" "unprognostic (4.10e-2)" "unprognostic (1.24e-2)" "unprognostic (1.69e-2)" "prognostic unfavorable (3.08e-5)" "prognostic favorable (3.67e-4)" "unprognostic (1.42e-1)" "unprognostic (1.87e-1)" "unprognostic (1.70e-1)" "unprognostic (6.78e-3)" "unprognostic (1.50e-3)" "unprognostic (2.59e-3)" "unprognostic (2.75e-1)" "unprognostic (1.67e-1)" "unprognostic (4.75e-3)" 11.6 11.2 9.6 14.7 10.0 20.4 23.1 11.0 10.5 15.7 10.8 13.0 12.0 15.5 19.7 12.5 16.6 12.1 9.7 10.1 10.1 12.2 8.9 12.3 24.3 9.7 9.5 17.9 18.3 13.9 15.3 11.5 9.5 15.9 16.2 18.9 15.6 15.5 11.4 15.5 14.1 11.8 9.7 18.3 12.3 28.9 10.4 22.1 10.5 5.7 25.7 14.2 13.7 11.0 38.3 10.1 48.9 55.5 7.5 11.6 57.2 17.4 10.8 19.7 23.8 33.6 18.1 76.8 23.9 10.1 30.2 28.7 30.5 14.5 29.3 15.1 23.8 51.2 22.2 28.7 20.0 64.1 14.8 7.4 27.2 13.7 30.3 10.2 15.2 32.4 31.0 27.9 22.3 19.3 41.7 44.5 40.1 22.6 18.1 40.4 23.4 24.9 11.4 16.9 26.0 20.9 17.3 12.2 31.3 16.0 10.8 49.4 12.9 18.5 22.4 9.1 23.4 66.4 44.9 131.2 17.9 29.0 17.1 3.2 6.6 11.7 7.2 12.3 10.5 22.8 9.8 9.0 9.6 21.6 11.5 7.2 2.8 12.2 14.1 8.7 11.7 6.4 9.6 10.0 11.0 10.5 10.1 10.1 9.7 9.5 9.5 9.7 10.4 11.0 15.8 6.4 15.0 48.3 28.4 18.9 19.2 20.0 19.9 15.2 19.6 17.3 8.4 11.5 26.5 11.0 27.1 26.6 21.9 7.7 3.9 11.1 3.7 31.1 12.7 11.2 7.2 21.5 60.1 12.9 8.2 15.4 11.7 12.6 8.8 21.9 6.8 6.2 10.5 13.5 66.8 8.6 20.3 9.8 14.1 7.4 15.5 11.3 14.2 51.5 15.8 12.8 17.5 49.3 59.5 13.9 8.2 13.5 45.2 15.7 7.9 7.5 69.2 27.7 13.1 17.8 15.9 155.3 96.5 16.2 20.6 14.1 19.9 8.4 11.9 16.3 KDM1A "AOF2, BHC110, KDM1, KIAA0601, LSD1" ENSG00000004487 "Lysine demethylase 1A" O60341 1 23019443-23083689 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Developmental protein, Oxidoreductase, Repressor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 131.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005884, HPA053660" Supported Supported Nucleoplasm,Cytosol "Intracellular and membrane" NA NA 7700 "Cluster 37: B-cells - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 14: REH - Unknown function" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm Cytosol "CAB005884: AB_443964, HPA053660: AB_2682220" "unprognostic (1.03e-1)" "unprognostic (1.17e-1)" "prognostic favorable (6.31e-4)" "unprognostic (1.50e-1)" "unprognostic (6.83e-2)" "unprognostic (3.95e-2)" "prognostic unfavorable (4.47e-12)" "unprognostic (1.80e-2)" "unprognostic (1.99e-2)" "unprognostic (9.41e-2)" "unprognostic (3.34e-3)" "unprognostic (2.13e-1)" "unprognostic (2.61e-1)" "unprognostic (1.41e-1)" "unprognostic (3.73e-2)" "unprognostic (7.74e-2)" "unprognostic (1.39e-1)" 25.7 30.8 24.7 23.5 25.8 48.1 30.6 26.5 27.0 33.1 20.4 31.6 26.4 36.0 46.9 35.0 34.2 25.3 26.1 25.3 28.2 24.7 22.3 24.5 34.7 19.8 22.0 41.4 36.2 51.2 41.5 31.5 21.0 32.2 33.8 30.9 36.6 29.4 47.3 38.2 29.2 30.1 21.2 25.2 29.3 86.9 27.4 55.8 28.5 34.0 37.2 34.6 31.5 21.8 128.1 64.7 180.8 160.7 47.0 59.5 128.4 53.1 66.4 106.0 93.7 61.2 120.5 94.5 74.1 87.6 53.7 139.5 169.5 101.0 133.3 86.3 102.7 133.0 105.7 150.6 59.6 103.7 56.0 55.6 71.4 112.8 78.9 93.0 134.1 171.7 148.0 43.4 76.3 75.9 227.3 79.2 118.3 70.8 93.0 214.7 119.1 64.1 89.0 81.0 225.0 169.9 239.4 62.4 80.2 126.1 62.7 76.2 109.5 47.0 78.4 88.1 73.6 55.6 47.1 109.3 49.2 120.4 68.3 2.0 2.5 4.3 4.1 4.3 3.4 7.4 3.5 3.8 3.1 2.1 4.5 4.9 0.2 3.0 5.5 6.8 4.4 1.4 24.7 25.8 26.5 27.0 25.3 28.2 19.8 22.0 21.0 21.2 27.4 21.8 18.7 19.2 29.1 33.6 15.9 18.6 27.1 19.9 33.0 27.5 20.4 22.1 24.4 11.5 19.0 23.9 27.1 31.6 18.1 15.7 17.6 35.4 43.5 45.9 49.3 20.4 22.8 29.7 51.1 24.7 57.2 24.8 23.4 44.4 12.0 49.5 16.8 17.2 15.0 15.2 51.2 24.9 22.4 15.1 19.7 20.3 21.5 20.2 12.4 30.0 28.1 19.3 12.3 50.3 30.4 28.1 13.5 23.0 28.9 26.3 17.2 15.7 29.5 19.8 0.0 22.2 25.0 131.8 67.1 36.1 12.8 16.6 15.4 34.3 27.6 20.5 KDM5A "JARID1A, RBBP2" ENSG00000073614 "Lysine demethylase 5A" P29375 12 280057-389320 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, Dioxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 45.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006201 Supported "Nuclear bodies,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 5: NTERA-2 - Transcription" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nuclear bodies" Cytosol "HPA006201: AB_1079160" "unprognostic (2.75e-1)" "unprognostic (1.68e-1)" "unprognostic (1.83e-1)" "unprognostic (1.12e-1)" "unprognostic (4.46e-2)" "unprognostic (1.60e-1)" "unprognostic (3.53e-3)" "unprognostic (1.81e-2)" "unprognostic (5.81e-2)" "unprognostic (3.19e-1)" "unprognostic (1.77e-3)" "unprognostic (6.11e-2)" "unprognostic (1.79e-2)" "unprognostic (1.10e-1)" "unprognostic (1.52e-1)" "unprognostic (2.60e-2)" "unprognostic (7.69e-2)" 8.1 8.7 5.8 11.4 8.3 45.5 11.1 11.6 8.5 8.6 10.0 8.2 7.2 9.7 7.1 8.9 7.6 8.0 5.2 6.2 6.5 7.8 9.9 8.8 15.3 6.8 5.7 11.0 9.4 10.1 4.2 11.8 6.5 8.6 9.9 9.6 6.7 7.3 5.5 12.5 7.3 9.4 6.0 13.5 8.8 21.1 6.7 21.6 9.1 7.6 14.4 8.7 7.2 15.0 14.4 25.3 18.3 14.2 16.1 15.2 20.3 12.5 16.5 18.4 19.8 15.2 17.0 24.0 3.9 21.0 16.0 13.3 19.2 14.2 21.9 37.9 15.9 29.3 26.5 9.0 13.0 38.6 22.1 16.6 13.1 22.6 29.9 18.8 18.8 21.0 17.9 32.7 15.7 9.7 27.9 11.0 28.4 12.3 7.9 25.7 47.5 11.4 8.8 32.6 7.0 20.5 24.5 11.0 13.0 25.0 11.9 24.0 26.0 12.0 17.0 13.6 21.1 11.5 13.6 53.7 15.5 16.5 18.0 64.5 21.8 44.4 31.4 25.0 32.3 27.1 24.6 25.9 22.8 32.0 26.3 22.8 63.0 35.8 28.9 32.0 20.9 22.5 5.8 8.3 11.6 8.5 6.2 6.5 6.8 5.7 6.5 6.0 6.7 15.0 53.1 64.1 61.6 61.7 80.6 33.0 22.2 30.1 48.9 69.0 35.3 27.9 38.2 31.5 39.0 35.0 116.7 48.8 103.3 51.3 3.9 37.4 96.8 60.2 72.8 51.6 69.7 51.3 71.7 31.6 34.7 47.2 39.8 99.8 54.4 106.9 42.8 30.9 30.2 87.5 59.1 40.0 40.7 52.5 37.5 32.5 48.4 63.9 26.6 57.1 82.9 48.3 105.0 68.3 85.9 38.7 37.0 55.7 73.1 32.4 33.6 11.8 40.2 71.9 59.2 64.0 59.9 137.1 104.8 50.1 47.6 71.1 80.1 67.5 40.1 42.0 KIAA0100 "BCOX, BCOX1, CT101, DKFZp686M0843, FMP27, MGC111488" ENSG00000007202 KIAA0100 Q14667 17 28614446-28645454 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042781 Uncertain Approved "Nuclear speckles,Cytosol" "Secreted to blood" No No "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 8: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles, Cytosol" "HPA042781: AB_10797020" "unprognostic (1.91e-1)" "unprognostic (1.03e-2)" "unprognostic (3.47e-2)" "unprognostic (5.26e-3)" "unprognostic (2.43e-1)" "unprognostic (6.89e-2)" "prognostic unfavorable (3.47e-5)" "unprognostic (4.99e-2)" "unprognostic (3.04e-1)" "unprognostic (3.03e-3)" "unprognostic (2.40e-2)" "unprognostic (2.53e-1)" "unprognostic (4.24e-3)" "unprognostic (7.58e-2)" "unprognostic (5.84e-2)" "unprognostic (1.22e-1)" "unprognostic (6.67e-2)" 36.1 30.7 22.4 28.5 20.7 31.5 30.6 18.2 23.5 22.7 31.7 30.8 19.7 23.1 25.7 31.3 29.2 20.5 24.2 24.4 21.3 43.0 18.6 30.7 28.4 29.9 24.4 23.9 24.4 51.8 25.2 29.6 29.3 27.1 34.8 27.5 28.9 27.1 51.9 31.8 26.7 35.3 20.2 28.8 23.3 24.9 26.5 32.3 35.4 42.5 34.9 30.3 16.0 20.6 66.5 123.8 61.4 58.8 109.3 64.8 44.8 60.9 80.1 72.3 67.6 85.9 29.4 92.0 71.2 111.2 75.3 86.2 91.4 89.6 87.1 102.8 88.7 73.2 95.9 47.2 47.0 129.1 121.3 66.5 68.2 98.0 74.1 56.1 104.9 64.1 70.6 29.0 66.8 94.4 94.5 61.1 26.9 119.0 46.6 71.7 69.0 60.0 43.4 116.9 60.2 46.5 76.8 205.5 50.7 76.0 123.2 88.6 98.1 55.0 60.4 74.5 116.2 27.2 33.8 58.0 62.8 81.7 65.4 0.3 1.1 1.5 1.2 1.0 1.2 1.1 0.5 1.0 1.3 0.6 0.6 0.7 0.7 0.8 1.2 2.9 0.7 0.7 22.4 20.7 18.2 23.5 24.4 21.3 29.9 24.4 29.3 20.2 26.5 20.6 21.5 16.0 17.8 15.0 16.5 10.3 8.9 8.7 15.4 31.7 19.3 14.7 30.2 14.3 13.0 12.9 29.2 15.3 34.4 30.5 5.9 9.9 19.4 20.4 16.1 16.4 12.1 14.1 19.1 11.0 9.4 14.1 21.4 16.4 8.2 20.4 18.5 30.5 10.6 28.6 18.3 16.4 8.2 31.5 18.6 23.2 9.3 19.9 10.6 14.0 25.3 14.3 21.6 11.6 12.7 9.8 12.1 6.4 17.1 15.8 17.9 15.1 15.1 22.5 0.0 20.3 20.1 30.5 28.1 22.9 11.1 45.6 17.0 24.2 22.6 11.7 KIF11 "Eg5, HKSP, KNSL1, TRIP5" ENSG00000138160 "Kinesin family member 11" P52732 10 92574105-92655395 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Motor protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 19.4;lymphoid tissue: 37.9" "Cell type enhanced" "Detected in many" "Erythroid cells: 39.1;Granulosa cells: 20.7;Spermatocytes: 38.0;Spermatogonia: 23.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA006916, HPA010093, HPA010568, CAB017617" Enhanced Supported "Mitotic spindle,Cytosol" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "Mitotic spindle" "CAB017617: AB_2131098, HPA006916: AB_1848033, HPA010093: AB_2668281, HPA010568: AB_1848034" "unprognostic (1.53e-1)" "unprognostic (1.11e-2)" "unprognostic (1.59e-2)" "unprognostic (3.35e-2)" "unprognostic (2.12e-1)" "unprognostic (7.82e-2)" "prognostic unfavorable (8.19e-7)" "prognostic unfavorable (3.27e-4)" "unprognostic (1.24e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (2.30e-4)" "unprognostic (6.59e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.35e-3)" "unprognostic (7.23e-2)" "unprognostic (9.08e-2)" "unprognostic (2.01e-1)" 1.1 0.7 0.5 8.5 0.7 19.4 2.5 0.4 0.6 1.4 0.5 6.3 5.5 1.8 1.0 6.7 1.0 1.2 0.6 0.5 0.5 1.0 1.1 1.3 17.5 0.6 0.6 0.6 0.5 0.7 0.3 3.9 0.6 1.0 7.4 0.8 1.3 0.7 0.2 6.0 5.3 2.5 0.5 2.9 3.9 11.6 0.4 37.9 1.6 0.3 18.5 2.3 2.3 0.6 103.1 45.2 100.6 94.5 7.3 10.5 24.2 72.6 62.8 78.8 78.1 39.6 67.2 111.1 36.5 34.4 32.9 72.0 72.1 36.5 92.4 68.3 41.3 70.5 41.4 42.4 1.4 116.0 63.0 3.6 3.3 61.4 55.9 18.3 50.0 46.1 51.2 126.4 61.1 41.4 99.3 65.8 40.3 42.5 30.7 106.6 98.8 40.2 21.0 30.1 30.0 42.9 56.4 25.9 29.2 34.1 67.9 37.6 28.6 35.7 51.3 37.1 96.9 35.4 58.3 113.4 29.5 82.3 50.3 0.8 0.0 0.1 0.0 0.3 0.3 0.6 0.4 0.4 0.2 0.1 0.1 0.2 0.2 1.0 0.1 0.1 1.1 0.2 0.5 0.7 0.4 0.6 0.5 0.5 0.6 0.6 0.6 0.5 0.4 0.6 0.4 0.0 2.0 1.3 3.5 2.9 1.1 1.6 3.4 1.0 1.8 1.8 1.7 1.5 2.5 1.8 0.0 6.7 2.3 2.9 1.9 0.5 16.3 3.4 4.3 2.0 0.0 39.1 2.1 0.6 11.4 4.7 9.2 4.9 0.0 20.7 2.2 0.4 8.2 0.0 1.8 4.3 4.1 4.6 3.4 4.4 0.9 4.0 0.0 0.0 1.0 0.7 2.1 2.5 1.1 0.2 0.4 0.7 15.2 0.8 0.5 0.6 3.7 0.4 0.0 1.7 3.7 38.0 23.4 12.6 3.3 1.5 4.5 2.5 8.0 1.7 KIF14 KIAA0042 ENSG00000118193 "Kinesin family member 14" Q15058 1 200551497-200620751 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Motor protein" "Ciliopathy, Disease variant, Meckel syndrome, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.5;lymphoid tissue: 10.9" "Cell type enhanced" "Detected in many" "Erythroid cells: 27.1;Granulosa cells: 13.2;Spermatocytes: 22.8;Spermatogonia: 16.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA038061, HPA058220" Uncertain Supported "Midbody ring,Cytosol" Yes Yes "Cluster 18: Basophils - Vesicular transport" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "Midbody ring" "HPA038061: AB_10669515, HPA058220: AB_2683642" "unprognostic (1.84e-1)" "unprognostic (7.15e-2)" "unprognostic (2.00e-2)" "unprognostic (1.87e-2)" "unprognostic (2.74e-1)" "unprognostic (1.51e-1)" "unprognostic (1.18e-3)" "prognostic unfavorable (8.64e-4)" "unprognostic (8.47e-3)" "unprognostic (1.02e-1)" "unprognostic (2.54e-5)" "unprognostic (2.31e-2)" "unprognostic (0.00e+0)" "unprognostic (6.28e-3)" "unprognostic (3.31e-1)" "unprognostic (8.14e-2)" "unprognostic (7.44e-2)" 0.2 0.2 0.1 2.0 0.0 6.5 0.3 0.2 0.3 0.2 0.1 0.9 1.2 0.3 0.0 1.0 0.0 0.2 0.0 0.1 0.1 0.0 0.3 0.2 3.2 0.1 0.2 0.0 0.0 0.0 0.0 0.9 0.1 0.0 1.2 0.1 0.1 0.0 0.0 1.0 1.1 0.6 0.0 0.6 0.6 2.5 0.1 10.9 0.1 0.0 3.2 0.4 0.3 0.1 29.7 17.3 26.8 15.0 0.8 3.0 14.8 20.0 11.7 18.7 16.8 10.5 15.1 18.0 7.0 9.6 11.6 23.0 21.6 13.3 26.7 22.1 11.3 28.8 24.8 10.3 0.1 45.5 15.7 0.6 0.6 20.9 17.8 4.0 13.5 26.3 44.0 22.6 23.5 12.1 26.9 14.2 22.6 8.7 15.0 24.3 35.4 22.8 6.3 8.3 12.7 14.0 28.3 9.5 11.0 19.8 12.9 11.6 11.1 14.7 17.3 16.2 35.3 8.2 8.9 25.8 8.6 24.0 30.5 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.2 0.3 0.1 0.1 0.1 0.2 0.1 0.0 0.1 0.1 1.0 0.0 0.0 0.0 1.9 2.4 1.0 1.1 0.6 2.3 1.5 1.9 0.8 0.0 0.9 0.0 2.1 4.2 0.6 2.5 0.0 0.2 4.1 3.7 2.2 1.6 0.0 27.1 1.1 0.0 7.7 3.3 10.2 5.0 2.5 13.2 2.5 0.9 5.4 0.0 0.9 5.2 0.0 2.9 1.9 2.5 0.6 2.3 0.0 0.0 0.4 0.5 0.0 0.5 0.8 0.3 0.0 0.7 11.3 1.2 0.2 0.1 1.4 0.8 6.6 1.4 2.1 22.8 16.3 8.3 0.9 1.4 2.3 0.7 4.3 1.9 KIF20A RAB6KIFL ENSG00000112984 "Kinesin family member 20A" O95235 5 138178719-138187723 "Predicted intracellular proteins" "Protein transport, Transport" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 14.1;lymphoid tissue: 24.6;testis: 11.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 11.0;Erythroid cells: 24.6;Extravillous trophoblasts: 13.1;Granulosa cells: 11.1;Spermatocytes: 21.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "NK-cell: 6.6;T-reg: 2.5" "Group enriched" "Detected in many" 46 "NK-cells: 6.6;T-cells: 2.5" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA036909, HPA036910" Approved Uncertain "Nucleoplasm,Cytokinetic bridge" Yes Yes "Cluster 15: NK-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cytokinetic bridge" "HPA036909: AB_10670245, HPA036910: AB_10671716" "unprognostic (7.50e-2)" "unprognostic (2.43e-1)" "unprognostic (1.39e-3)" "unprognostic (1.21e-2)" "unprognostic (3.47e-2)" "unprognostic (2.60e-2)" "prognostic unfavorable (2.14e-12)" "prognostic unfavorable (6.79e-4)" "unprognostic (2.86e-2)" "unprognostic (3.16e-1)" "prognostic unfavorable (1.90e-4)" "unprognostic (9.73e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (9.05e-2)" "unprognostic (2.61e-1)" "unprognostic (1.09e-1)" "unprognostic (3.16e-1)" 0.7 0.8 0.0 4.5 0.1 14.1 1.3 0.1 0.1 1.0 0.1 3.3 3.5 1.4 0.0 6.6 0.4 0.8 0.5 0.0 0.1 0.4 0.9 0.9 8.6 0.1 0.2 0.2 0.2 0.1 0.0 5.4 0.1 0.2 5.1 0.0 1.0 0.1 0.1 4.4 2.8 5.8 0.0 1.9 2.1 11.7 0.5 24.6 0.5 0.1 13.1 1.6 2.0 0.1 87.8 59.5 127.8 84.4 6.7 12.3 53.9 75.0 68.9 162.3 121.4 111.9 80.5 38.8 39.2 96.5 60.6 85.9 121.7 142.5 160.9 56.4 57.4 57.2 101.1 70.7 0.3 28.2 25.1 4.8 2.3 86.2 49.5 27.1 106.7 53.9 24.4 70.4 113.9 81.5 47.6 26.7 80.6 51.8 63.7 51.2 128.5 39.5 43.9 42.3 37.8 37.5 144.1 47.9 30.9 161.6 60.8 28.5 51.1 41.6 60.5 38.0 126.4 36.0 37.5 42.0 26.7 81.1 82.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 2.5 0.3 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.1 0.0 0.5 0.1 0.3 0.0 1.7 0.0 0.8 0.4 0.4 2.9 0.0 0.0 1.1 1.3 0.3 0.0 0.7 0.0 0.0 11.0 0.1 2.8 0.0 0.1 1.0 1.0 1.9 1.7 0.0 24.6 0.0 0.0 13.1 3.1 2.6 1.3 4.5 11.1 3.3 0.4 6.1 0.0 0.0 1.6 6.1 2.2 0.4 2.0 0.3 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.4 3.0 0.3 1.2 0.0 0.9 0.0 0.0 0.5 4.4 21.7 7.5 5.3 0.4 1.0 0.7 0.8 3.4 0.6 KIF20B "CT90, KRMP1, MPHOSPH1, MPP1" ENSG00000138182 "Kinesin family member 20B" Q96Q89 10 89701590-89774939 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Motor protein" Oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 10.2;lymphoid tissue: 9.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 89.2;Spermatocytes: 165.4;Spermatogonia: 96.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA050214 Supported Supported "Nucleoplasm,Cytokinetic bridge,Midbody,Cytosol" Yes Yes "Cluster 6: Non-specific - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cytokinetic bridge" "Midbody, Cytosol" "HPA050214: AB_2681053" "unprognostic (2.13e-1)" "unprognostic (3.01e-2)" "unprognostic (1.72e-2)" "unprognostic (3.20e-2)" "unprognostic (2.65e-1)" "unprognostic (7.39e-2)" "unprognostic (8.95e-5)" "unprognostic (3.32e-3)" "unprognostic (2.01e-2)" "unprognostic (8.14e-2)" "prognostic unfavorable (1.21e-4)" "unprognostic (1.62e-2)" "prognostic unfavorable (3.06e-6)" "unprognostic (4.22e-3)" "unprognostic (2.70e-1)" "unprognostic (2.51e-2)" "unprognostic (6.43e-2)" 1.3 0.7 0.3 4.5 1.0 10.2 2.5 2.4 0.4 1.5 0.1 3.2 3.6 2.3 0.4 3.3 1.2 1.3 0.9 0.3 0.3 1.3 1.3 1.5 8.0 0.5 0.3 2.7 0.7 1.1 0.2 2.4 0.6 1.3 4.0 1.1 1.0 0.9 0.4 2.5 3.4 2.2 0.4 3.3 2.5 6.9 0.6 9.8 1.8 0.7 7.5 1.6 0.7 0.6 84.8 17.0 24.3 21.7 4.7 8.0 20.2 33.8 30.9 34.8 36.3 22.6 38.1 32.5 10.4 17.3 13.0 41.8 27.3 18.9 46.4 39.5 18.6 33.1 30.5 19.5 1.4 57.1 26.3 3.4 2.8 33.7 33.9 12.2 22.8 17.0 32.2 36.5 31.3 14.6 33.6 10.8 25.0 13.8 16.1 23.1 47.8 14.3 10.7 11.2 7.7 13.9 24.4 11.0 12.2 17.3 28.5 16.3 17.9 22.2 22.1 29.1 55.3 10.1 29.5 43.2 21.1 49.4 16.8 13.1 2.4 4.2 5.5 4.1 6.8 13.0 7.4 6.1 1.3 16.0 8.6 8.0 0.2 3.0 4.5 5.2 9.5 2.2 0.3 1.0 2.4 0.4 0.3 0.3 0.5 0.3 0.6 0.4 0.6 0.6 11.5 3.2 13.5 2.3 36.4 17.7 6.2 20.8 6.8 14.3 8.3 8.5 8.7 1.5 10.7 0.0 10.4 21.4 32.3 8.8 3.9 6.9 13.1 10.6 13.2 11.0 1.2 89.2 8.1 4.7 38.1 13.2 14.8 12.9 44.4 37.2 9.3 4.4 20.7 13.5 9.5 8.6 16.2 21.0 17.9 10.5 8.1 17.1 5.4 23.4 11.3 7.5 24.7 9.0 9.1 4.1 5.7 8.6 51.4 3.7 8.9 3.2 6.6 9.8 6.6 16.9 17.1 165.4 96.7 26.1 14.1 5.2 34.2 12.9 25.5 5.2 KIFC1 "HSET, KNSL2" ENSG00000237649 "Kinesin family member C1" Q9BW19 6 33391823-33409896 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 39.7;lymphoid tissue: 47.5" "Cell type enhanced" "Detected in many" "Early spermatids: 32.0;Erythroid cells: 62.3;Extravillous trophoblasts: 39.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "T-reg: 1.6" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA055997, HPA062674" Enhanced Approved Centrosome NA Yes "Cluster 40: NK-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Centrosome "HPA055997: AB_2683001, HPA062674: AB_2684829" "unprognostic (7.33e-2)" "unprognostic (1.28e-2)" "unprognostic (2.17e-1)" "unprognostic (2.65e-2)" "unprognostic (1.41e-1)" "unprognostic (2.30e-2)" "prognostic unfavorable (7.07e-8)" "unprognostic (6.34e-3)" "unprognostic (9.36e-3)" "unprognostic (8.58e-2)" "prognostic unfavorable (4.21e-4)" "unprognostic (1.83e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (5.17e-2)" "unprognostic (6.66e-2)" "unprognostic (1.48e-1)" "unprognostic (4.52e-1)" 1.1 1.1 0.2 10.6 0.3 39.7 2.2 0.3 1.2 2.5 0.4 8.0 8.8 1.8 0.2 11.7 0.8 1.5 0.6 0.7 0.3 0.8 1.0 2.3 24.6 0.4 0.7 2.0 0.7 0.3 0.6 5.5 0.5 0.9 8.2 0.4 2.1 0.2 0.2 9.8 8.1 4.1 0.2 5.3 4.7 12.3 0.6 47.5 0.7 0.4 24.9 2.7 3.9 0.5 133.5 47.9 120.6 124.2 5.2 8.1 64.0 82.5 48.4 122.6 104.6 80.6 53.3 120.2 38.3 41.5 102.0 88.1 87.1 60.7 79.7 114.3 60.3 93.9 71.6 73.5 0.5 96.0 75.7 2.5 4.7 73.2 38.8 13.8 64.2 87.5 76.0 112.3 81.0 86.2 125.7 103.2 47.5 67.6 48.4 129.7 110.7 61.4 38.4 42.8 100.1 57.2 54.3 91.9 44.1 51.3 78.7 105.4 32.2 74.6 104.6 56.2 128.9 58.2 132.4 126.1 18.8 94.8 101.0 0.4 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.6 0.2 0.2 0.0 0.0 0.0 1.0 0.3 0.0 1.6 0.5 0.2 0.3 0.3 1.2 0.7 0.3 0.4 0.7 0.5 0.2 0.6 0.5 0.4 0.0 2.5 1.0 4.1 5.6 1.5 4.6 2.2 0.4 2.8 2.2 0.5 0.0 1.9 0.0 0.0 18.7 3.7 8.8 0.0 0.7 32.0 2.7 1.9 2.4 0.0 62.3 0.3 0.0 39.6 4.2 4.1 6.1 1.3 15.0 1.8 0.3 14.3 0.0 0.3 8.0 2.0 2.4 9.8 12.0 0.3 4.7 3.6 1.0 3.1 0.3 0.0 1.0 0.6 0.3 2.1 0.7 12.0 0.9 2.1 0.7 0.8 0.5 0.0 2.5 7.5 13.9 9.6 14.4 3.7 6.7 5.7 0.6 12.1 3.1 KNL1 "AF15Q14, CASC5, CT29, D40, hKNL-1, hSpc105, KIAA1570, MCPH4, PPP1R55, Spc7" ENSG00000137812 "Kinetochore scaffold 1" Q8NG31 15 40594020-40664342 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Cancer-related genes, Disease variant, Mental retardation, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "bone marrow: 5.3;lymphoid tissue: 7.4;testis: 16.9" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 8.5;Extravillous trophoblasts: 11.3;Granulosa cells: 22.8;Hofbauer cells: 7.1;Proximal tubular cells: 11.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "HPA026624, HPA049647" Enhanced Enhanced "Nucleoplasm,Nuclear bodies" Yes Yes "Cluster 21: B-cells - Adaptive immune response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nuclear bodies" "HPA026624: AB_10601696, HPA049647: AB_2680840" "unprognostic (5.35e-2)" "unprognostic (1.01e-1)" "unprognostic (5.59e-3)" "unprognostic (4.22e-2)" "unprognostic (1.59e-2)" "unprognostic (5.66e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (2.11e-4)" "unprognostic (2.06e-2)" "unprognostic (1.43e-1)" "unprognostic (3.20e-4)" "unprognostic (2.22e-2)" "unprognostic (1.93e-12)" "unprognostic (3.07e-2)" "unprognostic (3.08e-1)" "unprognostic (8.45e-2)" "unprognostic (7.36e-2)" 0.2 0.1 0.1 1.9 0.0 5.3 0.3 0.2 0.2 0.2 0.2 1.3 1.6 0.3 0.2 1.0 0.1 0.3 0.1 0.1 0.1 0.5 0.7 0.4 3.6 0.1 0.3 0.0 0.0 0.3 0.0 1.3 0.1 0.1 1.4 0.2 0.2 0.0 0.0 0.8 1.7 0.7 0.0 0.6 0.9 16.9 0.3 7.4 0.3 0.1 3.4 0.5 0.2 0.1 19.1 9.3 18.0 13.8 0.5 2.6 8.6 20.5 8.1 16.0 13.1 11.6 7.2 11.9 6.1 9.3 12.0 21.9 17.6 9.7 16.3 21.4 5.0 35.5 15.5 3.9 0.0 26.2 17.8 0.5 0.4 10.8 6.4 2.1 13.8 20.9 22.9 19.2 18.3 6.1 23.5 6.1 9.4 11.3 9.5 21.2 25.8 5.9 2.6 15.6 15.9 7.7 17.7 10.6 2.1 5.9 11.1 9.0 13.1 18.7 16.3 21.9 11.7 7.5 27.9 22.3 7.6 18.5 18.1 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.3 0.5 0.0 0.1 0.1 0.1 0.1 0.0 0.6 0.0 0.1 0.0 0.2 0.2 0.1 0.1 0.1 0.3 0.1 0.0 0.3 0.1 0.3 0.0 0.5 0.0 1.1 0.0 0.0 0.0 0.0 0.0 1.1 1.1 0.0 0.0 1.8 1.8 0.0 8.5 2.6 0.0 1.9 0.2 0.0 3.5 3.5 1.9 0.0 0.0 0.0 0.6 11.3 4.2 0.0 2.9 0.0 22.8 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 2.1 0.0 0.0 11.5 0.7 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 3.7 1.9 1.7 0.0 0.0 KNTC1 "KIAA0166, ROD" ENSG00000184445 "Kinetochore associated 1" P50748 12 122527246-122626396 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 42.3" "Cell type enhanced" "Detected in many" "Early spermatids: 30.4;Erythroid cells: 29.5;Plasma cells: 28.7;Spermatocytes: 40.7;Spermatogonia: 39.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA025241 Approved Supported "Plasma membrane,Cytosol" NA Yes "Cluster 18: Basophils - Vesicular transport" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 24: NB-4 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "Plasma membrane" "HPA025241: AB_1852629" "unprognostic (1.17e-1)" "unprognostic (2.12e-3)" "unprognostic (2.51e-1)" "unprognostic (1.53e-2)" "unprognostic (9.34e-2)" "prognostic favorable (8.69e-4)" "prognostic unfavorable (4.79e-6)" "unprognostic (4.04e-2)" "unprognostic (7.20e-3)" "unprognostic (1.59e-2)" "unprognostic (4.78e-2)" "unprognostic (1.92e-2)" "prognostic unfavorable (7.89e-8)" "unprognostic (2.17e-2)" "unprognostic (3.08e-1)" "unprognostic (8.04e-2)" "unprognostic (1.74e-1)" 7.1 7.6 3.7 11.7 3.6 42.3 7.6 4.9 5.3 9.1 3.5 9.8 9.0 5.3 5.2 12.2 6.8 3.4 4.1 3.6 3.4 6.7 6.4 8.0 16.4 3.8 3.4 8.2 6.6 2.9 5.7 5.8 3.9 7.3 11.9 5.5 7.7 2.9 2.5 15.1 14.5 4.6 3.1 18.2 7.2 28.2 4.0 17.8 5.4 1.4 17.4 6.2 8.9 5.0 33.8 27.6 77.8 17.9 5.9 10.8 35.0 30.6 19.8 29.7 27.9 26.2 27.6 40.2 15.6 14.9 19.5 45.4 34.1 19.1 39.1 28.8 23.7 49.7 57.1 27.1 2.0 49.3 32.8 5.8 4.3 30.7 20.2 15.5 20.5 50.5 50.4 29.4 22.6 25.0 40.9 113.0 39.4 16.3 34.5 55.4 37.8 44.8 17.8 35.6 24.1 31.0 55.7 11.7 16.7 46.2 44.4 28.1 15.1 33.7 32.3 33.3 36.3 39.3 42.3 61.0 20.1 31.3 39.6 2.5 0.5 1.8 0.7 0.7 0.6 1.6 1.1 1.3 0.5 0.9 0.8 1.0 1.6 0.9 1.0 0.8 0.5 0.3 3.7 3.6 4.9 5.3 3.6 3.4 3.8 3.4 3.9 3.1 4.0 5.0 4.3 0.0 2.6 3.3 8.1 4.2 1.9 1.9 2.2 2.2 3.1 3.4 1.8 0.0 1.9 5.5 4.2 7.0 3.8 3.0 0.0 1.5 30.4 3.3 3.9 2.9 0.0 29.5 6.2 0.4 5.9 2.9 10.2 5.2 1.3 14.7 2.2 1.3 4.8 0.0 4.5 2.3 0.0 2.2 4.7 17.7 4.7 4.0 1.8 4.7 1.6 1.1 2.1 2.5 4.4 0.8 1.0 3.0 28.7 1.0 1.5 0.5 5.0 5.0 6.6 3.1 2.9 40.7 39.9 4.9 2.3 2.9 5.3 2.1 5.8 1.6 M1AP "C2orf65, D6Mm5e, SPATA37" ENSG00000159374 "Meiosis 1 associated protein" Q8TC57 2 74557883-74648338 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 8.0" "Group enriched" "Detected in some" 4 "Spermatocytes: 16.2;Spermatogonia: 22.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "NTERA-2: 2.1;RT4: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045420, HPA059302" Uncertain Approved Nucleoli,Mitochondria NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 5: NTERA-2 - Transcription" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Mitochondria Nucleoli "HPA045420: AB_10961177, HPA059302: AB_2683972" "unprognostic (1.76e-1)" "unprognostic (6.58e-3)" "unprognostic (1.26e-2)" "unprognostic (2.87e-1)" "unprognostic (9.15e-2)" "unprognostic (1.35e-3)" "unprognostic (1.86e-1)" "unprognostic (2.17e-3)" "unprognostic (3.42e-1)" "unprognostic (2.37e-1)" "unprognostic (2.00e-1)" "unprognostic (2.15e-2)" "unprognostic (6.11e-2)" "unprognostic (7.74e-2)" "unprognostic (1.87e-1)" "unprognostic (1.67e-1)" "unprognostic (1.46e-1)" 0.3 0.2 1.1 0.1 0.7 2.5 0.5 0.0 1.2 2.5 0.8 0.1 0.1 1.1 0.3 0.1 2.6 0.1 0.0 1.1 0.6 1.0 0.0 0.4 0.1 0.0 0.2 0.0 0.3 1.3 1.8 0.1 0.0 0.1 0.0 0.5 0.9 0.3 0.0 0.0 0.0 0.1 0.2 0.1 0.4 8.0 1.7 0.6 2.0 0.0 0.3 0.3 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.1 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.3 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.7 0.0 1.2 1.1 0.6 0.0 0.2 0.0 0.2 1.7 0.3 0.1 0.0 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.3 0.4 0.4 0.0 0.1 3.7 0.0 0.5 0.1 0.2 0.0 0.3 3.1 2.2 0.1 0.0 0.0 0.4 3.1 0.0 1.6 0.0 0.0 0.9 0.0 0.0 0.0 0.1 3.8 0.0 1.0 0.8 0.0 1.6 0.8 3.9 0.0 2.0 0.0 2.8 0.4 0.5 0.0 0.0 0.4 0.2 0.0 0.0 0.5 0.2 0.0 0.1 1.8 1.4 0.0 0.1 0.0 16.2 22.5 0.0 0.0 0.3 0.1 0.0 0.1 0.1 MAD2L1 "HSMAD2, MAD2" ENSG00000164109 "Mitotic arrest deficient 2 like 1" Q13257 4 120055623-120066858 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.9;lymphoid tissue: 5.7" "Cell type enhanced" "Detected in many" "Erythroid cells: 81.8;Extravillous trophoblasts: 119.2;Spermatocytes: 127.8;Spermatogonia: 76.2" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003348 Uncertain Approved Nucleoplasm NA Yes "Cluster 20: T-cells - T-cell receptor" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA003348: AB_10603014" "unprognostic (4.08e-3)" "unprognostic (7.31e-2)" "unprognostic (5.17e-3)" "unprognostic (1.10e-2)" "unprognostic (1.27e-1)" "unprognostic (5.54e-2)" "prognostic unfavorable (5.15e-5)" "prognostic unfavorable (2.17e-4)" "unprognostic (6.74e-3)" "unprognostic (1.47e-1)" "unprognostic (3.20e-3)" "unprognostic (3.87e-3)" "prognostic unfavorable (3.07e-11)" "unprognostic (3.06e-2)" "unprognostic (4.05e-1)" "unprognostic (1.03e-1)" "unprognostic (9.70e-2)" 0.3 0.4 0.5 2.1 0.6 5.9 1.2 0.8 0.7 0.5 0.2 2.2 1.8 0.7 0.3 1.6 1.4 0.4 0.5 0.5 0.5 0.4 0.5 0.4 4.0 0.4 0.4 0.5 0.2 0.4 0.1 1.4 0.5 0.6 2.6 1.0 0.3 0.5 0.2 1.0 1.9 0.8 0.4 0.8 0.9 2.3 0.4 5.7 0.4 0.2 3.6 0.7 0.5 0.6 27.2 11.6 26.9 17.5 2.8 3.4 11.5 21.0 11.8 21.5 16.5 15.7 16.3 39.6 6.8 7.6 9.5 7.1 27.1 16.1 30.0 18.8 18.8 22.0 10.5 14.9 0.8 36.3 12.0 1.9 2.3 14.6 9.1 5.4 12.6 16.4 26.7 22.0 11.4 12.0 35.0 15.6 18.3 14.1 13.0 17.8 35.9 16.2 8.7 10.3 28.4 20.1 10.5 12.8 6.5 12.9 8.4 13.0 7.8 14.2 16.1 14.6 27.0 20.1 23.2 25.7 13.3 18.4 19.1 0.9 0.1 0.1 0.4 0.1 0.6 0.5 1.2 1.0 0.1 0.4 1.1 1.1 0.3 0.9 0.2 0.7 1.3 0.5 0.5 0.6 0.8 0.7 0.5 0.5 0.4 0.4 0.5 0.4 0.4 0.6 2.4 0.0 1.3 1.0 11.5 17.3 7.3 23.5 4.0 9.7 7.2 8.3 3.4 1.5 6.0 7.3 2.1 52.0 7.6 7.5 0.0 3.4 2.4 31.3 6.0 5.4 1.8 81.8 1.3 1.5 119.2 13.7 8.6 7.8 15.2 34.6 3.9 2.9 27.9 20.2 1.2 13.7 36.7 7.3 13.4 4.8 4.7 6.1 8.8 0.0 3.1 12.3 5.2 0.5 1.0 1.6 3.7 1.5 33.1 5.0 3.7 7.2 12.9 3.8 13.1 7.3 14.9 127.8 76.2 26.0 8.9 10.8 20.1 11.9 29.2 8.7 MAJIN C11orf85 ENSG00000168070 "Membrane anchored junction protein" Q3KP22 11 64937517-64972108 "Predicted intracellular proteins" Meiosis DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 22.5" "Group enriched" "Detected in some" 8 "Distal tubular cells: 3.9;Proximal tubular cells: 9.5" "Cancer enhanced" "Detected in some" "cervical cancer: 1.0" "Region enriched" "Detected in single" 4 "cerebellum: 2.6" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.3" "Lineage enriched" "Detected in single" 5 "B-cells: 1.3" "Group enriched" "Detected in some" 10 "CAPAN-2: 7.5;SiHa: 3.5" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 83: Testis - Spermatogenesis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (3.37e-1)" "unprognostic (6.43e-3)" "unprognostic (3.69e-2)" "unprognostic (7.05e-2)" "unprognostic (9.64e-3)" "unprognostic (2.92e-2)" "unprognostic (4.46e-2)" "unprognostic (1.06e-1)" "unprognostic (9.11e-2)" "unprognostic (4.11e-2)" "unprognostic (1.61e-2)" "unprognostic (2.58e-1)" "unprognostic (1.48e-2)" "unprognostic (2.43e-1)" "unprognostic (2.79e-1)" "unprognostic (4.18e-3)" "unprognostic (1.76e-2)" 0.0 0.2 0.2 0.2 0.6 0.1 0.2 2.6 0.6 0.1 0.0 0.1 0.0 0.0 2.0 0.1 1.1 2.9 0.0 0.1 0.1 1.4 1.2 0.2 1.4 0.5 0.2 0.0 0.3 0.0 0.0 0.1 0.3 0.3 0.2 0.2 0.1 0.6 0.0 1.2 0.4 0.0 0.2 0.6 0.2 22.5 0.1 0.1 0.9 0.0 1.3 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 7.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.2 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 2.6 0.6 0.1 0.1 0.5 0.2 0.3 0.2 0.1 0.4 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.3 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 MAP10 "KIAA1383, MTR120" ENSG00000212916 "Microtubule associated protein 10" Q9P2G4 1 232804892-232808407 "Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 12.3;Cone photoreceptor cells: 22.9;Spermatocytes: 11.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MOLT-4: 6.8;NB-4: 6.7;REH: 5.5;THP-1: 10.1;U-937: 6.9" "Low region specificity" "Detected in all" HPA052496 Approved NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 43: THP-1 - Innate immune response" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA052496: AB_2681852" "unprognostic (2.70e-1)" "unprognostic (6.18e-2)" "unprognostic (4.41e-2)" "unprognostic (6.05e-2)" "unprognostic (4.41e-1)" "unprognostic (3.06e-2)" "unprognostic (1.87e-2)" "unprognostic (4.60e-1)" "unprognostic (6.84e-2)" "unprognostic (1.04e-1)" "unprognostic (6.26e-3)" "unprognostic (2.03e-2)" "unprognostic (1.73e-3)" "unprognostic (3.97e-2)" "unprognostic (3.42e-1)" "unprognostic (1.37e-1)" "unprognostic (7.98e-2)" 1.0 1.0 0.5 1.2 0.7 0.7 1.8 0.2 0.8 1.6 0.0 0.9 1.4 1.1 2.6 0.5 1.3 1.3 2.6 0.6 0.6 1.1 2.5 1.2 2.7 0.7 0.2 2.2 1.7 0.7 0.8 1.1 0.6 1.0 0.8 3.6 1.5 0.9 2.6 0.4 1.7 1.3 0.2 1.5 1.5 3.1 0.2 3.7 2.2 1.5 2.0 0.9 0.5 0.5 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.8 0.6 0.2 0.3 0.0 4.0 0.0 2.0 1.6 0.0 0.0 0.0 0.9 0.6 1.5 0.0 0.2 0.2 0.0 1.7 2.6 0.0 2.4 0.2 0.2 0.0 0.3 3.1 0.0 1.0 0.0 1.4 1.9 6.8 6.7 0.0 1.7 0.0 5.5 0.0 1.9 1.4 1.6 3.3 2.7 0.0 0.3 0.0 0.9 0.6 10.1 0.7 0.0 1.7 0.2 1.2 1.9 0.0 0.0 1.5 6.9 0.1 5.1 1.9 1.7 0.5 1.4 0.6 0.6 0.8 0.2 2.5 1.3 1.2 0.9 0.0 1.2 3.2 2.9 1.4 0.7 0.5 0.7 0.2 0.8 0.6 0.6 0.7 0.2 0.6 0.2 0.2 0.5 4.4 0.0 1.1 0.7 1.6 0.4 0.3 1.0 1.2 12.3 1.0 1.0 4.9 5.7 2.1 0.0 22.9 0.7 1.9 0.7 0.0 2.9 3.1 1.0 2.2 2.6 0.0 0.4 4.2 3.0 0.5 1.8 1.5 0.5 1.3 3.4 0.4 1.3 1.5 0.0 3.5 2.3 6.1 1.2 0.8 2.2 0.6 1.1 0.0 1.0 5.6 3.2 2.1 2.5 3.2 1.7 0.3 0.7 0.7 0.2 1.9 0.2 1.5 8.5 0.0 2.4 1.2 11.2 6.1 0.8 0.3 0.3 1.3 4.4 2.0 0.4 MDC1 "Em:AB023051.5, KIAA0170, NFBD1" ENSG00000137337 "Mediator of DNA damage checkpoint 1" Q14676 6 30699807-30717447 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Spermatocytes: 74.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "NK-cell: 3.2" "Lineage enriched" "Detected in single" 4 "NK-cells: 3.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006915 Enhanced Supported "Nucleoplasm,Nuclear bodies,Focal adhesion sites" No No "Cluster 48: NK-cells - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoplasm, Nuclear bodies" "Focal adhesion sites" "HPA006915: AB_1853669" "unprognostic (8.52e-2)" "unprognostic (4.32e-1)" "unprognostic (4.11e-2)" "unprognostic (2.66e-2)" "unprognostic (1.60e-1)" "unprognostic (1.61e-1)" "unprognostic (5.40e-3)" "unprognostic (1.13e-1)" "unprognostic (1.09e-2)" "unprognostic (9.44e-2)" "unprognostic (2.74e-3)" "unprognostic (1.31e-1)" "unprognostic (1.62e-2)" "unprognostic (3.86e-2)" "unprognostic (2.99e-1)" "unprognostic (4.39e-3)" "unprognostic (3.23e-1)" 11.3 7.0 2.7 8.6 3.2 13.0 10.9 4.1 5.2 12.4 3.3 11.0 4.9 13.7 8.5 6.2 12.3 4.6 9.5 2.4 4.1 8.2 9.7 9.5 10.2 4.5 3.3 16.8 10.8 8.6 12.8 7.4 3.5 10.1 6.9 14.1 9.1 8.2 11.0 9.4 10.9 8.9 2.0 11.3 8.4 28.2 3.4 14.5 16.4 5.8 11.3 10.7 9.3 3.6 36.7 11.1 47.4 34.8 6.3 10.0 23.0 14.8 10.0 25.2 21.3 22.7 8.5 37.7 17.5 17.0 23.5 20.2 63.0 28.6 34.9 29.9 65.6 43.4 28.7 12.5 4.1 27.1 16.9 7.9 9.2 48.6 27.3 9.0 11.5 25.7 61.0 36.7 19.1 14.7 14.6 20.0 20.6 8.4 7.8 33.2 24.7 37.4 11.0 10.7 39.9 23.2 11.5 26.2 13.5 29.1 21.8 16.8 13.8 24.8 26.4 19.2 26.3 19.3 21.6 34.5 7.8 63.9 34.3 0.1 0.1 0.1 0.6 0.1 0.3 0.4 0.4 0.5 0.1 0.7 0.5 0.5 0.0 3.2 0.1 0.7 0.0 0.3 2.7 3.2 4.1 5.2 2.4 4.1 4.5 3.3 3.5 2.0 3.4 3.6 9.7 16.0 13.0 10.1 13.4 4.5 5.5 5.6 15.9 11.5 6.8 8.6 7.6 7.2 5.7 5.5 8.4 7.9 11.0 2.5 3.9 5.3 4.7 8.0 8.7 9.7 6.7 14.5 8.3 6.2 11.4 11.2 4.1 13.7 17.1 12.8 6.1 12.0 6.7 5.0 8.1 3.3 12.2 6.0 5.7 3.9 7.8 7.3 1.8 11.2 5.9 10.6 14.4 12.5 9.9 5.2 1.1 6.0 16.9 2.9 1.2 3.0 8.0 17.1 13.1 16.2 8.3 74.5 18.0 8.7 3.7 1.9 12.1 7.7 6.0 1.9 MEIOB "C16orf73, MGC35212" ENSG00000162039 "Meiosis specific with OB-fold" Q8N635 16 1833986-1884294 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Meiosis "DNA-binding, Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 34 "testis: 37.0" "Cell type enriched" "Detected in some" 6 "Spermatocytes: 499.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "HMC-1: 27.6;K-562: 92.7;THP-1: 76.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 1: K-562 - Erythropoiesis" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "unprognostic (7.18e-2)" "unprognostic (1.91e-1)" "unprognostic (3.04e-2)" "unprognostic (9.73e-2)" "unprognostic (1.67e-1)" "unprognostic (7.68e-3)" "unprognostic (2.00e-2)" "unprognostic (2.68e-2)" "unprognostic (7.30e-3)" "unprognostic (1.34e-1)" "unprognostic (3.80e-1)" "unprognostic (2.18e-3)" 0.2 0.1 0.3 0.0 0.2 0.1 0.0 0.1 0.3 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.1 0.2 0.3 1.0 0.3 0.0 0.0 0.1 0.1 0.3 0.1 0.0 0.2 0.2 0.2 0.1 0.0 0.8 0.0 0.0 0.1 0.7 0.2 0.0 0.1 0.0 0.1 37.0 0.2 0.9 0.2 0.0 0.0 0.0 0.1 0.2 0.0 0.9 0.1 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.2 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 27.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 92.7 0.1 0.0 1.5 0.0 0.0 4.2 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.4 0.6 9.4 0.8 0.0 0.4 1.1 76.2 1.2 0.0 0.0 0.1 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.1 0.3 0.2 0.3 0.1 0.1 0.2 0.1 0.2 0.2 0.0 0.0 0.0 0.7 0.1 0.0 0.2 0.0 0.0 0.5 0.1 0.3 0.8 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.5 58.0 0.1 0.3 0.2 0.0 0.0 2.6 0.0 0.2 0.2 0.0 0.2 4.5 2.3 0.0 0.0 0.1 3.3 4.1 0.0 0.0 0.0 0.0 15.9 1.8 0.2 0.0 0.0 0.0 0.1 0.0 1.0 2.1 0.1 0.0 1.5 0.0 0.3 0.0 3.4 0.0 0.3 6.6 0.0 0.3 499.7 75.2 0.6 0.4 0.0 0.0 0.8 0.0 0.4 MSH2 "COCA1, HNPCC, HNPCC1" ENSG00000095002 "MutS homolog 2" P43246 2 47403067-47663146 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" DNA-binding "Cancer-related genes, Disease variant, Hereditary nonpolyposis colorectal cancer, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "testis cancer: 46.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009572, HPA066845, CAB070867" Approved Supported Nucleoplasm,Vesicles NA Yes 28000 "Cluster 48: NK-cells - Unknown function" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Vesicles "CAB009572: AB_2144828, CAB070867: , HPA066845: AB_2732752" "unprognostic (2.35e-1)" "unprognostic (1.54e-2)" "unprognostic (2.89e-3)" "prognostic unfavorable (4.44e-4)" "unprognostic (2.23e-1)" "unprognostic (6.31e-3)" "prognostic unfavorable (1.72e-9)" "unprognostic (1.77e-1)" "unprognostic (7.09e-3)" "unprognostic (8.57e-2)" "prognostic unfavorable (4.63e-4)" "unprognostic (5.38e-2)" "unprognostic (3.29e-3)" "unprognostic (1.20e-3)" "unprognostic (5.74e-1)" "unprognostic (8.46e-2)" "unprognostic (1.48e-1)" 8.1 7.5 8.3 12.8 10.5 15.7 15.7 14.6 10.6 9.7 12.2 11.9 7.8 11.7 14.0 9.5 12.4 5.8 10.1 9.6 9.0 8.2 6.7 8.1 23.7 8.6 8.0 8.7 6.5 14.8 6.2 11.6 9.5 8.6 15.0 34.9 8.5 7.7 7.1 11.1 9.3 8.8 8.5 10.8 8.1 16.2 7.9 32.6 15.8 7.2 25.0 7.9 6.4 8.9 114.3 35.3 103.3 57.9 7.3 21.2 64.3 62.9 33.3 80.9 76.9 72.3 50.1 141.2 84.6 23.8 56.6 49.8 78.6 37.4 122.3 68.1 55.8 99.3 42.3 65.6 7.7 97.7 34.9 12.3 11.2 68.1 19.0 19.1 45.2 3.9 165.1 34.0 63.1 44.2 119.6 75.4 195.7 69.3 45.1 151.1 182.2 84.4 35.8 57.3 85.9 91.6 58.4 49.2 48.0 83.6 46.9 38.8 18.7 55.5 70.9 57.1 74.6 20.8 63.4 180.1 33.1 72.5 35.4 3.0 1.3 4.9 8.0 4.4 9.3 6.7 7.7 10.3 2.5 7.9 12.6 13.1 1.0 14.2 3.9 3.4 11.8 6.5 8.3 10.5 14.6 10.6 9.6 9.0 8.6 8.0 9.5 8.5 7.9 8.9 14.7 9.6 11.5 18.6 13.0 8.3 7.9 14.4 8.6 17.4 7.5 7.1 15.6 5.7 12.6 9.2 45.9 19.9 14.2 6.6 3.9 11.5 17.8 21.0 11.3 13.4 3.5 54.1 59.9 8.4 20.7 12.2 7.1 18.8 12.0 28.2 5.0 1.6 11.4 11.8 58.0 12.1 14.2 4.1 4.6 22.8 5.3 5.1 8.8 16.9 5.5 22.6 17.5 35.7 54.7 7.3 5.0 6.4 12.4 2.8 5.4 4.5 23.3 41.1 0.0 9.8 9.0 56.5 50.8 9.3 6.5 5.1 12.8 24.3 13.5 3.8 MSL1 "DKFZp686P24239, hMSL1, MSL-1" ENSG00000188895 "MSL complex subunit 1" Q68DK7 17 40121971-40136917 "Predicted intracellular proteins" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "neutrophil: 8.7" "Lineage enriched" "Detected in many" 5 "granulocytes: 8.7" "Cell line enhanced" "Detected in all" "SK-BR-3: 358.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022800, HPA023567" Uncertain Enhanced Nucleoplasm NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 72: Non-specific - Transcription" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA022800: AB_1853057, HPA023567: AB_1853059" "unprognostic (1.94e-1)" "unprognostic (6.28e-2)" "unprognostic (1.82e-1)" "unprognostic (1.45e-1)" "unprognostic (4.71e-2)" "unprognostic (5.39e-2)" "unprognostic (2.33e-2)" "unprognostic (1.60e-1)" "unprognostic (1.06e-2)" "unprognostic (2.24e-1)" "unprognostic (3.46e-1)" "unprognostic (7.48e-3)" "prognostic unfavorable (3.06e-6)" "unprognostic (2.92e-2)" "unprognostic (7.91e-2)" "unprognostic (5.80e-2)" "unprognostic (2.61e-2)" 60.2 52.0 34.3 48.0 33.6 56.7 56.7 26.1 39.6 76.6 16.1 62.7 51.7 75.1 55.9 48.1 77.5 38.6 46.8 32.1 26.5 57.1 43.9 61.5 50.8 24.1 25.7 58.3 59.3 47.8 78.8 48.5 22.2 59.8 46.8 41.1 56.5 51.9 63.6 60.8 61.6 53.7 21.8 88.2 57.1 66.2 27.9 62.3 79.8 51.6 51.6 53.3 62.0 27.7 35.9 42.2 88.3 57.9 78.5 67.6 45.0 61.6 65.3 76.1 68.4 42.4 37.8 78.8 45.6 65.0 48.4 65.2 74.7 40.5 78.2 68.0 59.6 43.6 60.5 50.6 40.9 59.7 81.6 56.9 63.6 56.1 46.5 77.4 71.0 47.2 69.3 62.8 61.4 22.8 95.0 64.8 37.6 39.4 27.2 77.1 48.7 72.1 55.4 38.9 80.9 48.0 57.5 358.8 46.5 80.1 83.5 81.0 58.7 51.0 56.4 37.8 52.3 98.5 58.5 77.7 52.0 43.7 60.7 0.0 1.0 0.8 1.7 0.6 0.8 1.1 0.9 1.3 0.7 0.9 0.9 0.8 8.7 0.7 0.8 1.4 0.6 0.5 34.3 33.6 26.1 39.6 32.1 26.5 24.1 25.7 22.2 21.8 27.9 27.7 44.1 28.9 40.7 42.7 22.7 50.0 37.8 21.7 69.4 55.2 41.6 32.3 29.5 25.8 25.8 11.0 12.5 15.4 43.8 36.4 3.9 17.2 16.1 35.8 53.9 43.3 31.2 22.3 39.8 20.7 15.4 37.4 20.4 48.1 3.8 24.8 36.4 35.9 25.2 52.2 33.4 29.1 8.2 36.4 42.8 28.5 58.4 34.2 32.0 33.7 30.6 31.3 30.9 25.1 32.4 24.7 32.1 39.9 26.8 72.7 35.4 9.0 32.7 28.4 39.5 29.2 40.7 71.8 49.2 57.5 65.8 17.0 29.9 27.5 31.4 58.7 MTBP ENSG00000172167 "MDM2 binding protein" Q96DY7 8 120445400-120542133 "Predicted intracellular proteins" "Cell cycle, Growth arrest, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Erythroid cells: 12.8;Excitatory neurons: 14.7;Oligodendrocytes: 16.1;Spermatocytes: 16.2;Spermatogonia: 10.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "SK-BR-3: 44.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "HPA025694, HPA050594" Uncertain Approved "Nucleoplasm,Nuclear bodies" Yes No "Cluster 22: NK-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nuclear bodies" "HPA025694: AB_1854169, HPA050594: AB_2681185" "unprognostic (1.92e-2)" "unprognostic (1.07e-1)" "unprognostic (4.47e-1)" "unprognostic (3.53e-4)" "unprognostic (1.20e-1)" "unprognostic (5.40e-3)" "unprognostic (2.77e-6)" "unprognostic (3.99e-3)" "unprognostic (1.50e-2)" "unprognostic (7.86e-3)" "unprognostic (3.38e-3)" "unprognostic (3.29e-1)" "unprognostic (5.20e-10)" "unprognostic (3.41e-3)" "unprognostic (2.51e-1)" "unprognostic (3.02e-2)" "unprognostic (5.86e-2)" 1.3 1.1 1.0 2.5 1.2 4.0 2.6 3.6 1.7 1.6 0.7 1.7 1.5 2.1 2.4 1.4 1.7 1.2 0.6 1.0 0.9 1.0 0.8 1.3 4.3 1.0 1.0 2.4 0.9 1.0 0.8 2.1 1.2 1.5 2.6 4.3 1.1 1.0 0.7 3.0 1.3 2.0 0.9 1.8 1.1 5.0 1.1 4.6 0.8 0.8 4.0 1.0 1.3 1.4 15.3 4.5 14.6 6.0 2.1 3.5 7.1 11.4 6.5 16.4 21.0 4.9 8.3 13.8 11.2 3.8 4.9 13.0 13.9 6.8 20.3 11.5 10.6 11.6 6.7 5.6 1.1 12.4 8.6 1.3 2.9 12.7 8.1 2.5 7.3 12.6 7.6 10.2 9.7 6.9 19.8 7.6 6.5 12.0 9.0 11.3 15.0 9.8 3.9 5.3 7.4 8.6 7.7 44.8 7.0 7.9 8.5 8.9 4.5 7.0 12.7 9.0 18.6 3.9 8.9 8.0 6.6 15.1 8.3 0.0 0.1 0.1 0.3 0.6 0.5 0.7 0.5 0.7 0.2 0.5 0.8 0.7 0.0 0.5 0.3 0.0 0.7 0.3 1.0 1.2 3.6 1.7 1.0 0.9 1.0 1.0 1.2 0.9 1.1 1.4 1.6 0.0 1.5 7.5 2.9 0.8 1.7 1.5 1.8 0.0 1.4 1.3 1.1 0.0 1.1 1.8 0.0 2.3 2.5 0.5 0.0 0.9 0.8 1.3 2.6 1.1 0.0 12.8 14.7 1.8 3.0 2.5 2.6 1.5 2.5 5.0 1.8 0.9 1.6 0.0 9.1 0.9 0.0 0.3 1.8 0.4 1.5 1.7 1.8 3.7 1.0 0.0 2.1 9.0 16.1 0.6 0.1 1.2 2.3 1.2 0.3 0.3 2.4 0.0 0.0 5.6 2.6 16.2 10.2 1.4 0.6 0.7 3.3 1.5 0.8 0.8 MTMR9 "C8orf9, DKFZp434K171, LIP-STYX, MTMR8" ENSG00000104643 "Myotubularin related protein 9" Q96QG7 8 11284816-11328146 "Plasma proteins, Predicted intracellular proteins" Endocytosis "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 84.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070944 Approved "Actin filaments,Centrosome" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 5: NTERA-2 - Transcription" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Centrosome "Actin filaments" "HPA070944: AB_2686325" "unprognostic (1.97e-2)" "unprognostic (1.95e-1)" "unprognostic (2.30e-2)" "unprognostic (1.32e-2)" "unprognostic (2.16e-1)" "unprognostic (2.64e-2)" "unprognostic (8.09e-3)" "unprognostic (3.25e-1)" "unprognostic (2.05e-1)" "unprognostic (1.46e-1)" "unprognostic (3.38e-2)" "unprognostic (1.12e-1)" "unprognostic (1.06e-2)" "unprognostic (1.07e-1)" "unprognostic (1.73e-1)" "unprognostic (3.08e-1)" "unprognostic (1.43e-2)" 4.6 3.7 7.8 4.3 7.9 3.4 4.9 7.0 8.1 3.5 3.3 6.5 2.4 4.5 2.9 3.4 3.1 3.2 7.5 8.4 8.7 4.4 3.0 3.5 4.0 7.2 8.4 3.6 2.9 4.2 3.0 4.2 8.0 5.0 3.1 17.5 2.6 3.9 5.7 3.8 3.1 5.8 6.3 3.8 3.0 7.7 7.4 3.5 3.7 8.6 3.9 3.7 3.2 8.1 2.9 4.2 7.1 4.8 8.4 7.1 5.0 8.7 5.6 5.1 4.3 3.7 1.5 6.8 2.1 8.1 5.0 3.7 5.2 5.3 6.7 1.2 3.8 6.8 4.5 3.4 8.9 2.2 5.0 6.9 5.9 6.2 9.1 5.8 7.8 3.8 5.0 3.9 10.5 2.1 3.9 2.6 12.4 6.9 4.0 3.0 9.7 2.0 7.7 5.1 2.2 10.6 4.6 2.7 6.7 10.5 2.7 5.4 11.2 7.9 2.3 4.8 4.8 1.3 1.9 3.3 6.9 5.6 7.9 0.2 0.4 0.3 0.7 0.4 0.5 0.5 0.6 0.5 0.2 1.1 0.7 0.7 0.5 0.5 0.4 1.0 0.4 0.2 7.8 7.9 7.0 8.1 8.4 8.7 7.2 8.4 8.0 6.3 7.4 8.1 17.8 12.8 16.8 26.4 27.7 13.6 11.6 12.9 11.4 0.0 11.7 8.4 25.3 24.3 14.5 14.7 0.0 12.4 27.4 7.4 3.9 11.6 17.7 5.1 15.0 18.9 16.2 10.8 44.8 7.1 12.7 18.3 4.6 8.0 14.0 24.9 26.7 17.3 14.5 0.0 42.1 10.7 12.2 21.0 32.7 8.5 23.3 20.2 16.0 18.7 24.3 0.0 25.7 32.2 48.7 15.0 11.1 19.5 11.7 21.6 13.4 10.9 18.0 0.0 39.5 19.0 17.7 84.9 33.1 10.1 12.9 4.5 20.7 14.6 9.5 9.3 MYT1L "KIAA1106, NZF1, ZC2H2C2, ZC2HC4B" ENSG00000186487 "Myelin transcription factor 1 like" Q9UL68 2 1789113-2331664 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Autism spectrum disorder, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 45.8;pituitary gland: 14.8" "Group enriched" "Detected in many" 4 "Excitatory neurons: 582.4;Inhibitory neurons: 635.5;Oligodendrocyte precursor cells: 265.4" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebral cortex: 45.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "SCLC-21H: 18.6;SH-SY5Y: 7.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060245 Approved Vesicles NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA060245: AB_2732643" "unprognostic (9.90e-3)" "unprognostic (3.74e-1)" "unprognostic (1.30e-1)" "unprognostic (9.61e-3)" "unprognostic (7.17e-2)" "unprognostic (3.73e-2)" "unprognostic (2.44e-1)" "unprognostic (2.36e-2)" "unprognostic (3.21e-2)" "unprognostic (1.93e-2)" "unprognostic (2.46e-1)" "unprognostic (7.96e-2)" "unprognostic (1.21e-2)" "unprognostic (1.04e-2)" 0.0 1.4 7.8 0.2 14.1 0.1 0.0 4.2 45.8 0.0 0.0 0.3 0.1 0.1 0.0 0.1 0.0 0.0 0.0 17.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.5 0.0 14.8 0.1 0.0 0.1 0.1 5.4 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.2 5.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 15.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.1 0.0 0.0 18.6 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.4 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.1 0.0 0.1 0.0 0.1 7.8 14.1 4.2 45.8 17.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 0.1 6.4 6.1 16.6 0.0 1.8 0.5 0.0 0.0 46.7 0.5 0.4 4.5 0.0 3.1 1.8 2.1 0.1 0.2 0.1 0.0 0.0 5.0 0.4 0.1 1.3 0.0 0.0 582.4 0.0 0.2 1.3 0.0 0.2 6.3 0.1 0.7 0.4 0.1 117.8 635.5 0.0 0.0 0.6 0.8 4.7 0.0 0.8 0.0 18.7 0.0 1.5 0.0 265.4 11.1 0.1 0.0 1.5 0.1 0.4 0.0 0.2 1.5 7.4 6.6 1.5 0.4 50.0 31.4 0.0 1.0 0.3 0.9 0.1 0.0 0.6 NCAPD2 "CAP-D2, CNAP1, hCAP-D2, KIAA0159" ENSG00000010292 "Non-SMC condensin I complex subunit D2" Q15021 12 6493356-6531955 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA condensation, Mitosis" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 76.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 48.0;Late spermatids: 34.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012423, HPA036947, HPA037363" Approved Supported Nucleoplasm,Nucleoli,Cytosol NA Yes 34000 "Cluster 44: Non-specific - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "Nucleoplasm, Nucleoli" "CAB012423: , HPA036947: AB_10671367, HPA037363: AB_10672483" "unprognostic (1.51e-1)" "unprognostic (1.88e-1)" "unprognostic (2.20e-1)" "unprognostic (1.31e-2)" "unprognostic (1.03e-2)" "unprognostic (7.84e-2)" "prognostic unfavorable (1.79e-8)" "unprognostic (2.73e-3)" "unprognostic (1.45e-2)" "unprognostic (5.00e-2)" "unprognostic (5.41e-3)" "unprognostic (4.53e-1)" "prognostic unfavorable (1.13e-7)" "unprognostic (4.80e-3)" "unprognostic (1.18e-1)" "unprognostic (4.53e-1)" "unprognostic (8.75e-2)" 8.3 7.4 7.3 21.5 11.4 35.5 10.9 9.9 8.3 10.2 7.4 17.9 17.0 10.7 10.6 15.9 11.2 9.8 7.6 7.2 8.0 7.4 4.8 10.6 38.1 11.0 10.0 8.0 7.7 11.3 5.5 17.5 11.7 9.4 20.4 11.1 11.8 10.2 7.9 21.9 16.0 13.4 8.4 16.1 12.1 18.2 10.2 76.8 11.3 10.2 44.8 10.1 9.3 13.9 125.3 99.3 134.6 97.9 29.9 28.4 159.2 76.1 69.8 138.3 109.1 123.5 150.8 135.8 24.2 63.2 126.7 128.6 188.0 105.4 194.1 214.1 92.8 112.2 113.8 79.4 12.5 145.0 96.5 20.5 31.6 112.4 107.8 61.9 89.9 94.0 71.0 63.4 104.7 79.6 162.2 73.8 207.5 129.9 78.2 153.7 260.6 77.7 39.5 64.1 54.0 61.9 121.5 64.9 44.3 189.1 27.0 101.7 51.0 94.1 149.6 60.8 168.4 45.3 51.7 181.0 55.7 92.2 126.1 11.0 1.7 3.7 7.1 2.8 5.3 5.1 6.4 7.3 3.4 3.5 7.3 7.3 1.4 8.1 2.2 4.1 8.3 3.9 7.3 11.4 9.9 8.3 7.2 8.0 11.0 10.0 11.7 8.4 10.2 13.9 4.3 6.4 7.4 4.9 11.0 3.6 3.8 4.4 17.1 3.7 4.7 6.9 4.1 5.7 3.4 1.8 8.4 13.5 8.9 7.3 0.0 4.5 18.3 5.3 6.3 5.4 1.2 48.0 5.6 3.7 17.8 6.4 7.1 5.8 3.8 20.0 8.9 3.3 10.1 5.0 5.0 9.9 6.1 16.4 4.4 34.3 5.9 10.8 0.0 2.8 9.5 11.8 15.5 2.5 17.8 5.3 4.6 6.0 22.6 4.1 6.0 2.4 4.2 8.4 0.0 4.2 5.2 21.3 13.7 19.3 3.4 6.3 12.0 6.1 14.7 4.1 NCAPG "CAP-G, FLJ12450, hCAP-G, YCG1" ENSG00000109805 "Non-SMC condensin I complex subunit G" Q9BPX3 4 17810979-17844865 "Predicted intracellular proteins" "Cell cycle, Cell division, DNA condensation, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 13.9;lymphoid tissue: 15.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 59.3;Extravillous trophoblasts: 26.6;Plasma cells: 20.4;Spermatocytes: 63.7;Spermatogonia: 24.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Region enhanced" "Detected in single" "white matter: 1.6" "Low region specificity" "Detected in all" HPA039613 Uncertain NA Yes 9500 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "HPA039613: AB_10805481" "unprognostic (5.23e-2)" "unprognostic (3.37e-1)" "unprognostic (1.59e-3)" "prognostic unfavorable (8.28e-4)" "unprognostic (4.22e-2)" "unprognostic (1.12e-1)" "prognostic unfavorable (3.13e-6)" "unprognostic (1.18e-3)" "unprognostic (1.63e-2)" "unprognostic (6.70e-2)" "prognostic unfavorable (7.65e-5)" "unprognostic (3.44e-2)" "unprognostic (0.00e+0)" "unprognostic (1.94e-2)" "unprognostic (1.34e-1)" "unprognostic (1.67e-1)" "unprognostic (2.07e-1)" 0.7 0.5 0.1 4.1 0.1 13.9 0.9 0.5 0.1 0.7 0.2 3.0 3.8 0.6 0.0 3.5 0.2 0.9 0.3 0.0 0.2 0.2 0.7 0.6 8.7 0.6 1.2 0.2 0.2 0.1 0.1 3.0 0.7 0.3 2.4 0.3 0.7 0.0 0.2 3.5 3.2 1.0 1.2 2.1 1.9 5.6 0.3 15.8 0.3 0.1 8.7 1.2 1.0 0.2 45.1 28.3 63.8 42.2 4.0 7.8 23.1 56.8 22.2 55.0 55.8 36.3 26.8 66.8 11.3 16.0 47.6 19.9 54.5 22.1 74.8 30.5 27.0 53.6 37.3 29.8 0.2 38.4 20.3 1.5 1.5 40.7 18.6 8.8 27.9 28.9 53.1 74.1 55.0 13.4 44.1 36.9 32.8 26.1 27.9 42.8 57.4 28.0 16.6 13.9 50.0 29.7 51.2 10.9 15.7 27.2 25.6 21.3 23.2 52.5 23.6 30.0 78.9 23.2 23.3 56.1 21.7 39.1 35.8 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.6 0.4 0.1 0.1 0.5 0.1 0.0 0.2 0.6 1.2 0.7 1.2 0.3 0.2 0.3 0.0 1.1 0.0 3.3 2.4 0.6 1.9 1.2 0.2 0.6 0.6 0.2 0.0 0.8 0.0 0.0 11.7 1.6 2.9 0.0 0.1 15.8 0.9 1.9 1.7 1.8 59.3 0.2 0.0 26.6 3.8 7.1 2.3 1.3 14.2 2.2 0.5 9.5 0.0 0.4 3.1 2.0 2.6 2.9 9.5 0.6 3.7 1.8 1.0 0.7 0.3 3.1 0.5 0.5 0.2 0.1 0.0 20.4 0.4 0.2 0.0 0.0 0.2 0.0 0.2 4.3 63.7 24.3 11.0 1.1 2.2 3.7 0.7 5.6 1.3 NCOA5 "bA465L10.6, CIA" ENSG00000124160 "Nuclear receptor coactivator 5" Q9HCD5 20 46060991-46089962 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050231 Uncertain Supported "Nucleoplasm,Actin filaments" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Actin filaments" "HPA050231: AB_2681058" "unprognostic (1.78e-1)" "unprognostic (1.54e-1)" "unprognostic (2.43e-2)" "unprognostic (7.93e-2)" "unprognostic (2.30e-1)" "unprognostic (1.43e-2)" "prognostic unfavorable (1.41e-5)" "prognostic favorable (8.07e-4)" "unprognostic (2.32e-1)" "unprognostic (7.75e-2)" "prognostic favorable (1.09e-4)" "unprognostic (7.46e-2)" "unprognostic (4.40e-1)" "unprognostic (2.06e-2)" "unprognostic (1.07e-1)" "unprognostic (8.78e-2)" "unprognostic (1.91e-2)" 19.1 17.0 15.8 18.5 16.7 9.5 19.6 21.7 17.4 25.1 17.2 22.2 14.2 24.8 19.4 18.6 21.8 12.2 15.6 16.1 17.6 18.8 15.3 15.2 25.1 16.5 15.7 28.5 20.5 20.3 21.8 18.7 15.2 21.4 16.3 23.1 20.4 14.6 19.6 21.9 21.6 17.7 15.7 25.7 19.2 25.8 16.9 26.2 20.7 14.6 25.0 20.8 19.6 17.4 39.5 34.2 47.4 49.0 22.2 23.3 37.8 26.7 24.0 42.5 34.7 47.8 30.6 64.3 44.0 26.0 36.1 51.2 39.6 33.5 36.5 39.1 19.9 38.7 33.4 40.7 23.5 53.4 36.1 16.8 43.8 22.5 20.4 22.2 30.6 33.1 36.3 50.9 33.9 50.9 74.2 41.3 43.2 33.3 41.8 55.6 31.4 28.0 25.1 44.3 42.5 38.5 42.8 51.7 37.3 26.9 41.1 62.3 28.7 44.6 33.8 27.1 42.2 32.9 50.5 43.2 31.1 31.1 29.1 3.9 9.5 13.4 13.4 10.3 15.4 13.1 14.3 13.6 9.8 17.7 13.3 12.4 7.0 8.8 10.7 21.6 10.0 7.1 15.8 16.7 21.7 17.4 16.1 17.6 16.5 15.7 15.2 15.7 16.9 17.4 7.3 9.6 12.6 24.2 12.5 6.4 3.1 6.7 10.8 13.2 9.7 8.0 5.2 10.0 7.3 9.2 22.9 11.2 11.8 8.2 0.0 8.9 7.5 6.9 11.7 9.1 9.5 9.7 29.4 12.4 8.8 7.9 12.2 7.7 1.3 11.6 9.3 9.3 7.8 3.3 31.6 10.4 4.1 10.1 3.2 5.0 13.7 6.7 3.6 42.2 9.2 7.4 13.4 19.6 35.8 11.7 3.2 15.4 12.1 4.4 4.5 5.2 8.6 9.0 6.6 10.7 7.0 28.1 15.7 8.7 5.4 6.7 8.7 8.4 9.2 3.6 NPAP1 C15orf2 ENSG00000185823 "Nuclear pore associated protein 1" Q9NZP6 15 24675775-24683393 "Predicted intracellular proteins, Transporters" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.8;testis: 2.9" "Cell type enriched" "Detected in some" 5 "Granulosa cells: 125.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA018828, HPA019562" Uncertain Supported "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "Vesicles, Plasma membrane" "HPA018828: AB_2669941, HPA019562: AB_2670190" "unprognostic (4.40e-2)" "unprognostic (1.85e-2)" "unprognostic (6.98e-3)" "unprognostic (7.45e-2)" "unprognostic (9.90e-2)" "unprognostic (1.08e-2)" "unprognostic (5.11e-3)" 0.0 0.0 0.9 0.0 1.8 0.4 0.1 0.1 1.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.5 1.7 0.9 0.0 0.0 0.1 0.9 0.7 0.5 0.4 0.0 0.5 0.0 0.5 0.1 0.0 0.2 0.0 0.0 0.1 0.3 0.0 0.0 0.5 0.1 0.1 2.9 1.5 0.0 0.5 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.9 1.8 0.1 1.1 0.5 1.7 0.9 0.7 0.5 0.5 1.5 1.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.1 0.2 0.7 0.1 0.0 0.0 1.2 0.0 0.0 0.1 0.0 0.1 0.0 125.9 0.0 0.0 0.1 0.0 3.5 0.0 0.0 0.0 0.0 0.8 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.3 24.1 12.7 0.0 0.0 0.0 0.0 0.5 0.0 0.2 NUP107 NUP84 ENSG00000111581 "Nucleoporin 107" P57740 12 68686951-68745809 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 89.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031679 Uncertain "Nucleoplasm,Nuclear membrane,Centrosome" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "Nuclear membrane, Centrosome" "HPA031679: AB_2673992" "unprognostic (2.89e-1)" "unprognostic (3.32e-1)" "unprognostic (4.10e-1)" "unprognostic (5.43e-2)" "unprognostic (1.60e-1)" "unprognostic (6.32e-2)" "prognostic unfavorable (3.12e-9)" "unprognostic (4.03e-2)" "unprognostic (1.23e-2)" "unprognostic (2.28e-1)" "unprognostic (1.17e-1)" "unprognostic (1.08e-2)" "prognostic unfavorable (1.28e-6)" "unprognostic (3.43e-2)" "unprognostic (2.05e-1)" "unprognostic (1.00e-1)" "unprognostic (1.96e-1)" 15.4 11.1 5.0 17.9 6.3 24.0 17.8 8.2 6.0 12.9 6.3 13.0 10.3 16.7 14.3 10.7 13.5 9.3 11.4 4.6 5.0 10.6 11.8 12.8 25.8 5.6 5.7 16.3 9.3 11.8 6.8 13.8 5.5 12.0 16.2 14.7 10.3 12.2 11.7 15.8 12.9 14.0 5.4 15.8 11.0 20.9 5.5 25.6 10.3 12.1 25.5 12.4 10.7 7.6 53.1 66.8 77.8 56.7 22.6 28.6 84.1 56.6 32.4 83.0 68.9 67.6 43.7 96.3 53.7 27.2 36.9 59.4 88.4 41.7 109.8 90.8 65.6 110.1 46.2 57.4 14.2 97.9 35.6 15.2 19.4 66.5 43.2 29.0 50.3 54.9 133.7 67.3 52.8 64.3 81.3 85.2 85.8 20.3 64.6 81.9 93.6 57.8 36.1 55.3 45.7 46.9 62.7 46.5 34.4 60.4 69.8 46.7 31.1 45.0 45.8 53.0 69.9 29.2 62.2 115.2 34.7 70.2 54.2 10.5 9.2 14.4 17.7 12.5 23.4 18.7 17.5 19.3 10.2 18.7 21.5 19.5 2.4 30.5 23.2 8.1 20.0 11.8 5.0 6.3 8.2 6.0 4.6 5.0 5.6 5.7 5.5 5.4 5.5 7.6 18.3 12.8 17.7 13.7 38.1 17.3 18.4 28.1 25.0 23.8 12.5 11.4 13.5 12.8 18.9 9.2 18.8 30.7 30.3 12.2 11.7 22.8 45.3 12.6 18.2 20.6 8.5 64.4 23.8 17.6 30.8 19.6 16.3 10.2 15.8 35.6 15.4 7.0 17.5 13.5 20.1 12.6 42.7 13.9 16.2 9.6 38.8 18.3 19.6 15.9 27.0 16.7 36.0 21.6 34.3 22.1 9.9 21.8 22.9 19.4 10.5 6.4 21.9 29.6 13.1 18.4 18.2 89.4 51.9 18.7 17.6 14.1 27.0 24.5 16.8 12.5 ORC6 ORC6L ENSG00000091651 "Origin recognition complex subunit 6" Q9Y5N6 16 46689643-46698394 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA replication" DNA-binding "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 10.3;lymphoid tissue: 7.4;testis: 9.6" "Cell type enhanced" "Detected in many" "Granulosa cells: 56.7;Spermatocytes: 102.6;Spermatogonia: 108.9;Theca cells: 47.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016330, HPA072587" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center" Yes No "Cluster 24: B-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nucleoli fibrillar center" "CAB016330: AB_670295, HPA072587: AB_2686537" "unprognostic (3.47e-2)" "unprognostic (8.99e-3)" "unprognostic (2.92e-1)" "unprognostic (4.47e-2)" "unprognostic (2.27e-1)" "unprognostic (2.19e-2)" "unprognostic (3.15e-6)" "unprognostic (1.36e-2)" "prognostic unfavorable (3.53e-4)" "prognostic favorable (1.48e-4)" "unprognostic (1.50e-4)" "unprognostic (3.97e-2)" "unprognostic (3.90e-14)" "unprognostic (2.08e-1)" "unprognostic (4.24e-1)" "unprognostic (2.79e-1)" "unprognostic (5.98e-2)" 0.3 0.7 2.0 2.2 1.6 10.3 0.6 1.5 1.9 0.7 1.0 1.7 1.5 0.8 1.1 4.1 0.4 0.6 1.5 1.9 1.8 0.4 0.9 0.6 7.4 1.5 1.9 0.4 0.3 0.7 0.6 3.3 1.7 0.3 1.9 0.3 0.7 0.2 0.1 1.1 1.5 1.0 1.6 2.4 0.8 9.6 1.8 6.2 0.5 0.3 7.3 1.2 1.3 1.8 28.6 27.4 43.7 33.9 5.4 6.8 31.6 54.2 20.2 59.3 30.9 39.3 18.0 35.6 27.1 10.5 29.1 29.9 57.9 15.1 50.4 17.2 46.4 27.9 13.2 40.1 6.6 46.5 23.7 1.8 2.6 32.4 17.1 9.3 20.0 30.1 36.0 17.4 35.9 26.9 65.6 60.7 48.1 20.7 76.0 78.6 80.6 35.8 14.9 9.8 52.2 30.4 24.5 29.8 18.1 34.9 15.6 37.9 11.6 53.7 34.6 33.6 51.8 12.5 18.9 123.2 22.2 29.5 40.1 0.0 0.3 0.3 0.9 0.7 0.4 0.7 0.5 0.5 0.6 1.4 0.8 0.3 0.0 0.8 0.8 1.0 1.2 0.7 2.0 1.6 1.5 1.9 1.9 1.8 1.5 1.9 1.7 1.6 1.8 1.8 1.6 3.2 14.5 1.0 8.8 6.6 2.2 3.6 8.6 6.6 4.1 5.8 3.7 1.5 6.3 5.5 4.2 39.3 6.0 9.5 1.9 2.5 13.2 6.5 7.5 4.3 1.8 45.4 6.3 0.7 40.9 8.0 7.1 9.4 1.3 56.7 0.7 9.9 15.7 11.8 2.7 12.4 6.1 3.8 11.9 8.9 2.8 7.7 33.8 2.8 1.2 2.5 2.1 0.0 2.0 2.1 1.4 3.4 18.5 2.6 2.3 1.0 10.7 10.2 0.0 5.1 7.3 102.6 108.9 16.9 6.0 10.9 7.5 47.5 14.4 2.7 PAFAH2 HSD-PLA2 ENSG00000158006 "Platelet activating factor acetylhydrolase 2" Q99487 1 25959767-25998117 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 48.7" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 43.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 52.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018157 Approved NA Yes "Cluster 2: Granulocytes - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA018157: AB_1854928" "unprognostic (9.89e-2)" "unprognostic (2.60e-1)" "unprognostic (3.63e-3)" "prognostic favorable (3.28e-6)" "unprognostic (5.19e-2)" "unprognostic (2.12e-1)" "unprognostic (1.05e-1)" "unprognostic (1.78e-1)" "unprognostic (2.43e-1)" "unprognostic (1.04e-1)" "unprognostic (4.46e-2)" "unprognostic (2.62e-1)" "prognostic favorable (0.00e+0)" "unprognostic (8.15e-2)" "unprognostic (8.17e-2)" "unprognostic (1.59e-2)" "unprognostic (7.27e-2)" 4.6 7.3 4.7 6.5 6.5 6.8 9.2 6.3 6.0 8.8 6.7 16.3 17.4 4.9 9.9 7.8 8.3 10.4 9.7 4.5 5.8 19.3 18.3 8.6 8.4 6.4 6.5 4.7 31.2 22.9 5.9 9.2 6.5 8.8 16.6 14.1 10.0 6.3 18.0 11.4 19.0 6.9 5.5 7.6 15.6 7.7 6.5 48.7 16.4 10.7 7.4 7.0 5.5 8.2 8.6 10.7 6.7 7.6 13.9 10.9 13.7 9.6 5.0 8.6 5.7 4.4 18.1 3.8 11.7 5.7 8.1 7.5 10.1 9.3 11.0 7.8 6.1 6.3 4.6 8.8 8.4 3.3 52.5 7.2 21.2 13.2 8.7 4.7 8.3 8.9 8.9 7.1 11.7 3.8 10.3 3.3 13.4 29.9 5.9 8.4 6.3 8.7 13.9 3.0 8.0 6.8 5.7 7.7 18.2 11.0 12.7 6.0 7.8 5.9 7.4 12.5 7.7 13.0 18.1 4.8 12.5 13.2 20.0 36.2 6.7 60.2 23.7 6.4 15.3 3.5 8.3 15.4 5.0 4.4 10.6 14.9 5.8 17.4 2.4 39.0 9.0 8.7 4.7 6.5 6.3 6.0 4.5 5.8 6.4 6.5 6.5 5.5 6.5 8.2 4.6 16.0 12.8 9.8 3.2 1.5 2.1 5.3 1.8 9.5 9.4 4.8 6.8 11.5 11.9 18.4 27.1 11.2 37.7 34.9 3.9 11.1 1.1 8.6 4.5 5.6 7.8 3.2 4.0 7.3 9.5 3.5 12.2 13.2 27.8 7.3 5.7 21.4 11.2 5.0 3.6 18.2 4.1 11.6 1.6 1.0 2.5 7.1 8.8 5.6 7.3 6.3 23.7 4.0 10.0 10.6 15.8 2.6 6.5 4.2 43.1 18.3 8.9 8.8 6.6 5.3 4.1 19.9 8.9 4.5 3.8 10.0 9.0 4.4 19.4 4.9 PAXIP1 "CAGF28, CAGF29, PAXIP1L, PTIP, TNRC2" ENSG00000157212 "PAX interacting protein 1" Q6ZW49 7 154943687-155003124 "Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 26.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "cerebellum: 12.0" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006694, HPA016950" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Vesicles" "HPA006694: AB_1855011, HPA016950: AB_2669489" "unprognostic (2.44e-2)" "unprognostic (1.28e-1)" "unprognostic (2.14e-2)" "unprognostic (2.66e-2)" "unprognostic (1.39e-1)" "unprognostic (1.63e-2)" "unprognostic (7.39e-3)" "unprognostic (2.65e-2)" "unprognostic (1.34e-3)" "unprognostic (1.19e-2)" "unprognostic (1.33e-1)" "unprognostic (2.36e-1)" "unprognostic (3.28e-2)" "unprognostic (4.99e-3)" "unprognostic (3.98e-1)" "unprognostic (2.44e-3)" "unprognostic (2.30e-1)" 4.3 3.9 2.3 5.8 2.5 9.8 5.4 12.0 2.6 4.8 2.7 4.9 4.8 4.6 4.8 5.4 4.2 4.4 3.9 2.3 2.4 4.6 5.7 4.2 8.8 2.8 2.6 5.7 4.4 6.2 3.8 6.1 2.9 4.4 4.9 3.9 5.7 3.6 5.9 6.5 5.7 3.7 2.5 5.6 5.2 8.7 2.6 26.6 5.5 4.6 6.0 5.3 4.7 2.8 17.7 14.2 18.4 31.2 7.8 6.5 16.4 7.6 8.0 10.3 11.9 15.7 13.6 22.9 9.4 9.1 21.3 13.6 23.7 12.1 12.7 23.0 18.4 17.4 10.7 13.6 5.5 23.9 22.3 6.3 9.0 10.3 4.2 5.8 9.9 22.8 24.3 15.1 10.4 24.3 51.1 19.9 29.8 17.1 9.5 28.8 18.7 24.8 10.7 14.6 14.6 9.4 20.3 14.9 9.5 16.6 11.4 20.1 5.1 8.6 1.5 12.3 18.6 15.2 9.5 31.0 21.1 27.7 23.6 0.2 0.9 0.5 0.9 1.1 1.4 0.5 1.5 1.1 1.0 0.9 2.4 0.7 0.5 1.3 1.3 1.2 1.2 0.9 2.3 2.5 12.0 2.6 2.3 2.4 2.8 2.6 2.9 2.5 2.6 2.8 5.2 6.4 6.3 18.9 5.8 6.4 5.1 4.7 4.0 18.9 8.9 6.6 6.9 7.2 7.1 9.2 10.4 9.0 3.8 6.8 5.9 3.9 2.3 5.5 6.9 5.2 2.4 10.3 21.4 3.3 8.0 6.9 5.6 6.5 2.5 8.8 5.0 9.2 4.4 3.3 24.2 8.4 2.0 6.1 7.1 2.8 8.7 4.8 3.6 15.9 6.3 8.0 7.2 27.2 27.4 4.4 4.3 9.4 4.9 8.0 5.2 4.2 4.3 12.3 0.0 11.1 5.1 22.6 18.7 8.9 7.0 6.2 4.9 6.3 9.8 4.5 PCGF6 "MBLR, RNF134" ENSG00000156374 "Polycomb group ring finger 6" Q9BYE7 10 103302796-103351144 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 76.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "unprognostic (7.73e-2)" "unprognostic (8.93e-3)" "unprognostic (1.72e-1)" "unprognostic (7.74e-2)" "unprognostic (1.11e-2)" "unprognostic (1.92e-1)" "unprognostic (1.02e-1)" "unprognostic (1.10e-1)" "unprognostic (1.77e-2)" "unprognostic (1.84e-1)" "unprognostic (1.71e-1)" "unprognostic (9.44e-2)" "prognostic unfavorable (4.54e-9)" "unprognostic (5.14e-2)" "unprognostic (2.48e-1)" "unprognostic (2.57e-3)" "unprognostic (4.53e-2)" 7.3 4.7 2.8 5.0 3.0 4.5 6.3 3.2 5.3 6.9 2.5 7.8 4.4 7.5 3.3 4.4 6.0 4.3 5.4 2.8 3.0 4.4 11.6 4.0 5.6 3.0 2.9 5.5 6.6 4.3 3.3 4.7 3.3 4.8 4.3 2.6 4.1 5.2 10.9 4.1 4.7 7.5 3.2 4.3 5.1 8.9 2.9 5.8 3.8 6.9 5.0 6.2 5.3 3.5 29.8 11.6 16.3 33.7 7.3 12.2 15.3 19.9 20.0 21.0 16.9 14.7 10.6 22.4 9.1 18.3 9.3 16.2 18.5 14.8 21.5 15.1 34.2 20.2 11.6 19.3 17.7 29.9 9.4 16.3 13.5 19.1 23.7 12.1 13.5 19.2 30.1 13.6 14.9 22.1 21.3 32.0 16.4 8.6 16.4 23.4 24.3 11.7 7.0 12.3 5.8 14.5 14.8 7.5 21.8 8.7 8.0 19.4 10.5 15.8 19.1 17.8 34.5 14.9 19.9 30.5 13.5 32.3 6.9 5.4 1.9 1.4 2.3 2.3 3.4 1.7 3.1 2.9 2.7 2.6 3.7 3.2 0.2 3.6 1.7 2.5 4.1 1.7 2.8 3.0 3.2 5.3 2.8 3.0 3.0 2.9 3.3 3.2 2.9 3.5 10.5 3.2 3.6 12.7 8.9 9.6 5.6 5.9 12.0 12.4 6.4 7.2 5.5 10.0 4.4 11.0 12.5 14.6 9.4 4.1 11.7 7.4 7.9 5.4 12.7 11.1 4.2 15.6 23.9 7.3 20.3 12.8 5.1 4.2 3.8 10.7 10.8 12.2 8.7 6.7 21.3 4.8 2.0 8.8 7.0 5.3 10.2 7.9 8.8 7.5 7.0 6.8 15.5 17.6 11.8 5.7 4.6 7.2 11.1 8.1 4.9 12.4 5.0 13.2 6.6 5.5 12.7 76.2 39.3 15.3 8.8 4.5 11.5 12.8 7.3 4.1 PCSK7 "LPC, PC7, PC8, SPC7" ENSG00000160613 "Proprotein convertase subtilisin/kexin type 7" Q16549 11 117204337-117232525 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "NK-cells: 310.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 8400 "Cluster 15: NK-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (7.11e-2)" "unprognostic (2.90e-2)" "unprognostic (8.33e-3)" "unprognostic (4.24e-2)" "unprognostic (1.32e-1)" "unprognostic (2.77e-2)" "unprognostic (1.56e-1)" "unprognostic (2.60e-1)" "unprognostic (1.96e-1)" "unprognostic (2.41e-1)" "unprognostic (8.80e-2)" "unprognostic (1.09e-1)" "unprognostic (1.02e-1)" "unprognostic (1.51e-1)" "unprognostic (1.06e-1)" "unprognostic (1.00e-1)" "unprognostic (3.03e-2)" 31.8 16.4 16.4 27.9 17.6 25.7 24.0 15.9 20.9 27.5 16.7 69.5 29.2 72.4 7.6 24.0 35.7 12.9 20.1 19.9 16.6 15.7 19.6 25.6 31.6 18.1 17.0 17.5 29.7 11.8 16.6 13.5 18.0 35.4 37.5 10.0 15.9 11.2 15.6 20.7 35.4 13.5 15.7 30.7 45.1 12.5 18.3 25.0 18.1 10.7 29.2 39.4 22.2 20.2 14.6 27.5 19.1 21.4 23.3 19.0 15.0 48.5 22.2 24.1 23.9 38.3 82.6 24.8 33.5 38.6 31.1 48.0 25.2 34.7 15.5 34.2 24.2 36.7 40.7 17.5 26.1 23.2 49.4 32.9 22.5 33.0 26.4 12.4 41.2 28.0 22.5 22.0 34.8 19.0 31.5 24.3 17.6 63.4 28.1 19.1 16.9 29.5 30.1 33.7 24.9 32.3 39.6 51.1 7.5 14.8 32.3 18.6 36.4 36.4 16.4 31.5 34.3 13.4 8.7 14.0 18.6 33.1 33.3 7.9 7.1 9.0 38.1 9.8 33.0 23.5 29.7 35.6 7.6 18.5 20.8 24.7 5.3 41.0 11.5 8.8 42.8 20.6 16.4 17.6 15.9 20.9 19.9 16.6 18.1 17.0 18.0 15.7 18.3 20.2 47.4 48.1 36.2 44.4 93.3 70.1 50.0 35.2 19.4 124.1 31.2 23.5 8.1 35.8 42.5 47.8 246.0 50.7 97.4 204.9 5.9 27.4 6.4 21.0 40.3 47.5 62.4 27.4 47.2 54.5 39.0 38.5 110.6 36.5 34.1 30.2 77.4 27.8 32.4 87.5 41.4 91.2 24.4 60.6 83.9 7.5 33.5 39.2 53.4 25.3 54.6 21.8 310.0 48.2 62.0 73.7 132.2 39.9 58.7 39.0 98.2 9.2 22.9 178.8 72.3 87.5 107.7 64.4 24.5 27.4 94.3 62.5 127.3 42.7 110.3 53.3 PIGO "DKFZp434M222, FLJ00135" ENSG00000165282 "Phosphatidylinositol glycan anchor biosynthesis class O" Q8TEQ8 9 35088688-35096601 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" Transferase "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014905 Approved Nucleoplasm,Nucleoli NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 30: Epithelial cell lines - Translation" "Cluster 55: Plasma cells - Humoral immune response" Nucleoli Nucleoplasm "HPA014905: AB_1855369" "unprognostic (1.41e-2)" "unprognostic (1.06e-1)" "unprognostic (4.03e-1)" "unprognostic (3.54e-1)" "unprognostic (1.09e-1)" "unprognostic (2.09e-1)" "unprognostic (6.98e-3)" "unprognostic (4.14e-2)" "unprognostic (5.08e-2)" "unprognostic (2.25e-1)" "unprognostic (3.63e-1)" "unprognostic (1.54e-1)" "prognostic favorable (3.05e-10)" "unprognostic (1.89e-2)" "unprognostic (1.30e-2)" "unprognostic (5.23e-3)" "unprognostic (3.81e-2)" 8.6 12.9 5.4 9.2 7.5 5.9 10.9 7.6 6.1 9.8 9.6 11.7 14.5 10.5 11.2 10.5 15.5 9.5 7.7 5.3 6.0 14.7 15.3 10.0 9.1 7.8 6.8 12.5 16.4 33.2 9.4 12.3 7.6 12.5 12.9 10.5 13.0 11.9 6.8 10.0 11.3 8.6 6.8 11.3 13.1 12.2 6.2 11.4 20.0 4.7 10.2 9.4 8.6 9.8 30.5 51.5 14.4 20.8 12.5 13.8 25.6 12.7 22.0 30.0 24.5 19.0 30.2 17.1 22.7 15.4 41.8 21.6 24.2 39.6 18.0 19.0 15.7 10.3 31.2 14.5 24.5 13.9 17.1 17.1 42.8 26.8 43.7 23.9 15.8 25.1 11.4 23.7 24.9 16.8 16.5 15.9 9.2 18.9 20.8 16.9 11.6 18.8 32.9 20.8 11.9 16.1 17.5 42.8 10.0 15.7 32.2 9.1 9.7 21.8 19.1 11.8 23.6 14.4 22.9 7.1 23.4 10.3 27.8 5.3 5.1 6.3 6.4 6.7 6.6 3.5 3.5 7.3 10.4 4.8 4.5 5.4 1.8 5.7 4.6 7.3 6.0 3.5 5.4 7.5 7.6 6.1 5.3 6.0 7.8 6.8 7.6 6.8 6.2 9.8 6.3 3.2 13.9 4.6 7.9 2.5 4.5 7.9 8.6 9.1 6.1 3.8 3.1 14.3 12.2 16.5 2.1 21.0 10.2 13.3 0.0 13.6 1.2 11.3 5.5 5.2 3.0 2.1 1.7 14.0 16.0 5.6 11.7 10.1 7.0 7.9 4.2 11.7 11.6 11.8 1.9 7.4 8.2 6.6 4.2 1.0 4.4 5.8 3.6 2.8 6.7 14.3 5.2 1.5 3.9 8.4 7.7 3.0 8.7 3.7 11.4 7.4 16.1 11.8 6.6 5.1 4.8 20.0 10.4 6.7 2.0 22.6 7.2 7.2 10.8 4.0 PLD6 ENSG00000179598 "Phospholipase D family member 6" Q8N2A8 17 17200995-17206333 "Metabolic proteins, Predicted membrane proteins" "Differentiation, Lipid degradation, Lipid metabolism, Meiosis, Spermatogenesis" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 32.4;Spermatogonia: 23.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 5.8;NK-cells: 6.3;T-cells: 11.9" "Cell line enhanced" "Detected in many" "HAP1: 41.2;REH: 31.5" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" HPA049345 Approved NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 43: Testis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "HPA049345: AB_2680722" "unprognostic (1.71e-1)" "unprognostic (6.80e-3)" "unprognostic (3.21e-2)" "unprognostic (1.39e-1)" "unprognostic (2.95e-2)" "unprognostic (8.21e-2)" "unprognostic (1.31e-1)" "unprognostic (7.83e-2)" "unprognostic (9.01e-2)" "unprognostic (1.48e-1)" "prognostic favorable (1.05e-4)" "unprognostic (1.32e-1)" "unprognostic (1.04e-1)" "unprognostic (6.08e-2)" "unprognostic (1.56e-1)" "unprognostic (3.51e-1)" "unprognostic (2.24e-1)" 4.6 4.1 11.5 1.4 10.8 2.0 3.8 10.7 11.4 7.6 10.3 9.0 1.7 3.5 5.0 1.6 5.7 2.2 5.2 10.9 12.1 2.9 5.9 2.8 3.0 10.3 14.6 7.9 5.0 5.7 8.1 1.8 14.0 5.6 1.7 3.6 3.2 4.4 5.2 4.5 3.2 2.4 8.7 4.3 4.5 21.2 13.1 1.6 3.3 1.4 2.2 4.3 4.4 11.1 7.1 5.4 0.2 6.0 2.3 0.9 0.3 2.2 3.6 4.0 2.4 6.3 2.0 15.4 3.3 2.2 2.4 1.9 41.2 1.2 3.8 9.7 12.0 14.9 4.2 11.3 10.2 11.2 6.0 2.0 4.4 2.4 9.7 4.5 1.0 7.1 13.5 0.4 4.6 9.0 8.3 15.8 0.1 8.0 7.4 31.5 3.1 11.3 3.7 0.5 23.4 9.7 2.8 3.9 7.2 4.3 3.8 17.8 1.1 0.1 0.3 9.0 4.5 1.9 7.5 0.1 4.8 11.4 8.6 0.4 0.4 0.2 2.9 0.3 9.9 5.8 11.3 6.0 0.1 4.8 11.9 5.5 0.5 6.3 0.2 1.5 9.4 4.1 11.5 10.8 10.7 11.4 10.9 12.1 10.3 14.6 14.0 8.7 13.1 11.1 0.6 3.2 3.3 4.6 3.3 5.5 4.5 1.7 9.6 4.5 2.2 3.9 7.2 1.5 1.9 1.8 0.0 5.5 0.5 0.5 1.9 1.4 7.1 7.5 1.5 0.8 1.2 3.4 6.0 0.7 1.3 2.8 1.5 3.4 1.3 3.3 1.8 2.1 2.7 6.7 9.8 2.0 6.1 0.6 1.7 2.7 4.4 0.8 3.6 2.8 0.7 6.5 0.0 3.0 7.1 1.0 0.1 4.9 10.1 5.9 0.8 1.4 6.0 1.3 0.0 1.4 1.5 32.4 23.7 1.3 1.6 0.8 3.6 5.6 1.5 1.2 PPP4R3A "FLFL1, FLJ20707, KIAA2010, MSTP033, PP4R3, SMEK1, smk-1, smk1" ENSG00000100796 "Protein phosphatase 4 regulatory subunit 3A" Q6IN85 14 91457508-91510554 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002568, HPA063917" Approved Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 59: Non-specific - Transcription" Nucleoplasm "Nuclear speckles, Cytosol" "HPA002568: AB_1079207, HPA063917: AB_2685153" "unprognostic (5.51e-2)" "unprognostic (2.93e-2)" "unprognostic (3.26e-1)" "unprognostic (1.40e-1)" "unprognostic (4.40e-2)" "unprognostic (9.95e-3)" "unprognostic (4.10e-2)" "unprognostic (5.71e-3)" "unprognostic (1.05e-1)" "unprognostic (8.34e-3)" "unprognostic (1.33e-1)" "unprognostic (3.85e-2)" "unprognostic (3.07e-1)" "unprognostic (1.13e-1)" "unprognostic (2.57e-1)" "unprognostic (1.57e-1)" "unprognostic (4.53e-2)" 19.3 13.5 14.4 18.2 14.5 50.0 19.6 16.6 15.2 19.1 16.2 21.2 17.2 20.0 15.9 21.4 20.4 12.3 16.2 12.6 13.3 18.3 23.7 20.2 28.3 13.6 14.2 22.0 19.8 16.8 14.8 17.5 13.7 18.4 18.5 10.9 20.8 13.1 24.5 25.4 24.4 15.0 12.7 24.1 20.6 22.3 14.5 27.4 17.7 16.7 25.4 19.5 19.4 16.9 24.5 41.4 34.1 27.1 22.5 20.9 60.9 23.2 21.4 24.5 24.6 35.2 32.1 63.1 30.2 19.2 15.0 27.8 36.6 28.9 39.8 52.0 19.7 32.5 25.7 24.5 26.3 59.1 33.1 15.1 50.4 19.7 31.1 20.1 26.7 29.4 33.5 36.2 33.1 52.1 42.8 38.0 31.2 46.5 29.8 54.0 40.6 26.5 30.3 41.5 41.6 25.4 35.3 77.0 32.5 33.6 39.4 37.8 28.0 19.2 20.6 21.1 26.8 36.0 67.0 69.3 25.2 31.8 34.7 6.2 1.9 2.9 4.9 2.6 6.6 4.6 4.5 4.4 2.1 7.4 5.6 4.8 2.5 9.0 3.7 5.0 6.9 2.6 14.4 14.5 16.6 15.2 12.6 13.3 13.6 14.2 13.7 12.7 14.5 16.9 44.1 32.1 48.3 0.0 83.0 0.0 46.7 0.0 58.1 27.9 35.9 23.5 0.0 32.9 30.3 46.0 20.9 33.9 91.8 21.1 29.4 21.2 13.0 86.9 46.5 33.3 13.3 47.5 0.0 25.1 29.0 27.3 45.3 70.7 20.2 39.8 28.9 51.8 25.8 32.0 0.0 28.2 0.0 48.7 0.0 8.5 37.6 70.7 0.0 0.0 41.8 21.0 44.3 0.0 0.0 27.8 25.7 42.5 75.8 56.6 37.3 23.5 16.8 27.3 26.3 45.9 27.1 91.0 59.9 58.0 0.0 44.3 80.1 33.0 25.8 75.2 PRC1 ASE1 ENSG00000198901 "Protein regulator of cytokinesis 1" O43663 15 90966040-90995629 "Predicted intracellular proteins" "Cell cycle, Cell division" Oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 89.9;testis: 55.0" "Cell type enhanced" "Detected in many" "Erythroid cells: 142.9;Extravillous trophoblasts: 68.3;Spermatocytes: 136.4;Spermatogonia: 74.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 34.4" "Lineage enriched" "Detected in many" 4 "granulocytes: 34.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA034521, HPA048816" Enhanced Supported "Nucleoplasm,Plasma membrane,Microtubules,Cytokinetic bridge,Midbody" Yes Yes "Cluster 38: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Microtubules, Cytokinetic bridge, Midbody" Nucleoplasm "HPA034521: AB_10670169, HPA048816: " "unprognostic (1.14e-1)" "unprognostic (3.98e-2)" "unprognostic (9.21e-2)" "unprognostic (1.75e-3)" "unprognostic (2.39e-1)" "unprognostic (3.43e-2)" "prognostic unfavorable (2.11e-4)" "unprognostic (1.24e-3)" "unprognostic (3.86e-3)" "unprognostic (1.65e-2)" "prognostic unfavorable (2.76e-5)" "unprognostic (2.49e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.09e-2)" "unprognostic (1.79e-1)" "unprognostic (7.90e-2)" "unprognostic (3.92e-2)" 7.4 6.2 6.4 10.0 6.1 89.9 6.4 10.3 8.4 8.1 5.0 16.3 10.6 5.7 2.3 37.6 6.0 3.0 6.9 5.6 4.9 5.6 4.8 9.0 16.9 4.8 5.2 8.1 8.9 2.6 3.6 15.3 5.2 4.9 16.5 4.9 9.5 1.5 4.1 20.1 13.0 9.4 4.9 12.5 11.7 55.0 4.2 43.0 4.3 2.3 24.9 4.8 13.7 5.6 167.9 199.9 164.8 113.6 16.8 28.7 87.5 237.8 139.3 257.2 195.3 134.6 158.5 65.5 91.4 151.9 156.9 220.9 188.8 101.2 240.6 118.7 206.4 135.6 263.5 123.5 4.1 71.4 109.0 7.7 12.8 145.8 146.9 56.6 146.4 100.5 114.0 132.4 241.1 144.4 66.9 98.5 66.6 216.4 84.9 69.7 205.1 86.3 115.3 123.6 151.2 118.9 225.4 121.9 82.7 112.3 149.1 127.1 91.2 168.2 146.0 140.5 345.1 43.5 127.7 80.0 74.5 162.0 265.3 34.4 0.6 2.9 0.6 0.1 0.4 1.1 1.3 1.3 2.4 0.5 1.2 0.4 0.4 3.0 0.3 2.6 8.0 1.0 6.4 6.1 10.3 8.4 5.6 4.9 4.8 5.2 5.2 4.9 4.2 5.6 2.5 0.0 3.1 1.3 6.8 16.6 6.6 8.0 2.2 6.4 3.4 4.3 3.2 0.0 7.6 3.7 0.0 45.5 2.8 16.5 0.0 3.2 41.5 4.5 4.0 4.7 5.4 142.9 5.0 2.9 68.3 7.2 16.3 6.8 8.9 13.2 9.3 2.1 21.5 3.3 5.2 17.0 10.2 8.7 15.0 15.4 3.7 5.2 3.6 1.9 5.5 3.8 4.1 2.0 1.7 2.3 3.2 1.9 17.5 5.9 2.0 0.1 3.2 4.6 6.6 7.4 10.9 136.4 74.2 38.0 14.2 14.6 6.8 0.4 24.1 6.7 PRIM1 ENSG00000198056 "DNA primase subunit 1" P49642 12 56731296-56752374 "Predicted intracellular proteins" "DNA replication, Transcription" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 28.2" "Cell type enhanced" "Detected in many" "Erythroid cells: 56.4;Spermatocytes: 118.2;Spermatogonia: 107.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040010 Uncertain NA Yes "Cluster 24: B-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA040010: AB_10805599" "unprognostic (3.04e-3)" "unprognostic (1.67e-2)" "unprognostic (2.12e-2)" "unprognostic (1.51e-2)" "unprognostic (4.63e-2)" "unprognostic (3.61e-2)" "prognostic unfavorable (2.40e-8)" "unprognostic (4.68e-2)" "unprognostic (2.73e-3)" "unprognostic (1.82e-3)" "unprognostic (1.56e-1)" "unprognostic (1.82e-1)" "unprognostic (1.98e-3)" "unprognostic (3.94e-1)" "unprognostic (2.16e-1)" "unprognostic (5.35e-2)" "unprognostic (6.53e-2)" 3.7 3.2 2.0 7.0 2.8 28.2 9.9 5.5 2.8 3.7 1.2 7.9 4.5 5.0 4.2 4.4 5.3 2.9 2.3 1.9 2.0 3.0 7.5 4.9 12.3 2.5 2.2 8.9 6.1 6.1 2.1 4.8 2.6 3.6 11.2 8.3 3.9 3.9 4.6 7.8 7.7 5.8 2.0 6.9 5.4 14.4 2.3 18.8 5.0 5.6 14.4 3.8 3.1 4.3 43.0 37.9 52.1 29.2 5.1 9.1 57.8 34.7 28.7 62.1 59.8 42.0 54.4 83.0 27.4 15.8 26.0 40.4 60.3 39.9 68.8 40.7 40.4 106.2 22.6 36.8 1.2 129.3 43.2 4.2 7.2 55.8 22.1 8.8 22.6 92.1 105.5 123.8 35.4 33.6 76.8 54.4 53.5 32.0 47.1 85.0 81.4 70.9 15.0 35.4 51.0 46.0 41.4 20.6 19.9 36.2 67.2 52.8 10.9 32.2 70.7 33.1 46.4 45.1 94.5 45.3 19.4 55.4 40.9 2.5 1.9 4.4 9.1 4.0 9.5 11.3 11.2 8.5 3.9 12.2 14.0 10.7 1.0 6.8 7.1 7.5 10.0 5.3 2.0 2.8 5.5 2.8 1.9 2.0 2.5 2.2 2.6 2.0 2.3 4.3 6.9 6.4 6.8 4.6 10.4 3.8 10.7 10.0 4.6 5.1 7.0 7.2 3.2 2.8 6.1 7.3 6.2 14.9 8.7 2.5 0.0 5.8 6.2 4.1 3.9 6.4 1.2 56.4 5.7 7.2 27.0 5.4 5.6 3.3 3.8 10.0 5.7 4.7 11.8 20.2 10.6 4.6 2.0 8.1 3.1 4.3 7.2 6.5 3.6 2.8 7.9 5.7 8.2 8.0 7.8 2.7 2.2 4.9 9.7 2.2 2.0 2.5 6.0 12.7 13.1 8.2 8.8 118.2 107.2 5.1 4.0 4.5 12.8 3.0 9.4 5.0 PRR23B FLJ46116 ENSG00000184814 "Proline rich 23B" Q6ZRT6 3 139019031-139020926 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 13 "testis: 1.3" "Group enriched" "Detected in some" 8 "Spermatocytes: 6.4;Spermatogonia: 3.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047473 Uncertain Uncertain "Nucleoplasm,Nuclear bodies,Microtubules,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes NA "Cluster 83: Testis - Spermatogenesis" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoplasm, Microtubules" "Nuclear bodies, Cytokinetic bridge, Mitotic spindle, Cytosol" "HPA047473: AB_2680062" "unprognostic (7.57e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.4 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 PSPC1 "FLJ10955, PSP1" ENSG00000121390 "Paraspeckle component 1" Q8WXF1 13 19674752-19783019 "Predicted intracellular proteins, Transcription factors" "Biological rhythms, Immunity, Innate immunity, Transcription, Transcription regulation" "Activator, Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 173.4;Inhibitory neurons: 164.7;Spermatocytes: 171.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038904 Supported Enhanced "Nucleoplasm,Nucleoli fibrillar center" No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "Nucleoli fibrillar center" "HPA038904: AB_10673291" "unprognostic (2.13e-3)" "unprognostic (3.48e-1)" "unprognostic (1.52e-2)" "unprognostic (1.25e-1)" "unprognostic (4.14e-3)" "unprognostic (2.14e-2)" "prognostic unfavorable (2.21e-4)" "unprognostic (1.13e-3)" "unprognostic (9.57e-2)" "unprognostic (1.09e-1)" "unprognostic (1.69e-3)" "unprognostic (3.04e-3)" "unprognostic (2.92e-1)" "unprognostic (3.69e-2)" "unprognostic (8.61e-2)" "prognostic favorable (1.46e-4)" "unprognostic (7.72e-2)" 10.9 13.0 11.5 13.2 11.5 53.7 16.2 12.8 13.9 12.5 9.9 14.9 12.4 14.8 21.7 14.0 16.2 12.1 11.1 11.8 10.6 12.2 8.9 9.9 20.8 12.1 9.0 13.7 9.5 9.5 10.3 13.8 10.6 11.0 15.5 17.4 10.0 8.3 20.9 14.4 12.4 12.6 8.7 11.1 12.0 25.0 10.5 23.1 12.2 12.7 21.9 20.4 10.0 15.8 50.5 20.4 46.6 23.3 18.9 19.8 60.3 26.1 34.0 48.3 43.6 68.4 27.8 67.8 27.7 27.9 25.4 24.6 54.7 32.2 50.0 28.9 27.3 76.4 14.1 83.1 37.4 55.3 46.7 31.6 6.5 29.8 32.9 19.2 41.7 65.9 42.8 26.1 43.2 54.1 65.5 52.8 65.5 27.3 28.0 43.7 46.8 34.6 50.8 74.6 42.7 22.0 35.8 59.1 23.1 44.9 34.5 56.6 25.1 28.9 27.7 28.0 25.4 22.5 14.5 115.1 13.2 32.7 35.2 14.8 21.3 14.5 11.8 22.7 12.0 23.3 15.1 11.0 19.1 22.5 15.4 11.2 16.9 11.9 18.1 20.9 21.8 15.7 11.5 11.5 12.8 13.9 11.8 10.6 12.1 9.0 10.6 8.7 10.5 15.8 21.0 19.2 29.5 79.3 36.4 33.3 24.9 16.4 23.3 43.2 24.6 21.0 28.6 21.5 18.9 16.5 58.4 70.0 41.0 16.4 21.5 31.3 17.4 40.0 33.9 24.0 25.2 23.1 173.4 34.1 104.7 25.1 25.5 39.4 9.5 28.0 23.9 11.1 27.2 30.3 164.7 20.0 12.2 25.7 25.3 21.4 31.4 27.7 19.6 92.8 45.2 25.5 27.8 115.6 156.4 26.8 22.2 26.7 31.8 16.5 16.1 23.8 25.9 69.1 32.9 27.2 27.4 171.5 75.4 24.0 34.1 80.4 38.9 48.1 27.2 26.2 QRICH1 "AB-DIP, FLJ20259, VERBRAS" ENSG00000198218 "Glutamine rich 1" Q2TAL8 3 49029707-49094363 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation, Unfolded protein response" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037677, HPA037678" Approved Enhanced Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 59: Non-specific - Transcription" Nucleoplasm "HPA037677: AB_10671883, HPA037678: AB_2675603" "unprognostic (2.38e-2)" "unprognostic (2.05e-1)" "unprognostic (8.29e-2)" "unprognostic (1.67e-1)" "unprognostic (2.41e-1)" "unprognostic (3.14e-2)" "unprognostic (2.77e-3)" "unprognostic (6.94e-2)" "unprognostic (2.82e-2)" "prognostic favorable (7.46e-4)" "unprognostic (1.12e-1)" "unprognostic (1.40e-2)" "unprognostic (2.17e-3)" "unprognostic (5.06e-2)" "unprognostic (3.84e-1)" "unprognostic (1.76e-1)" "unprognostic (1.06e-1)" 29.8 27.9 15.4 30.5 17.0 61.0 27.8 25.3 20.2 25.8 16.0 25.9 26.3 28.6 25.9 30.0 27.6 25.2 26.0 16.9 14.8 21.3 23.5 27.8 40.1 14.7 13.2 34.0 26.0 33.2 24.8 27.0 14.6 25.8 25.2 30.4 28.3 26.3 34.8 35.4 31.0 28.9 13.2 35.8 25.9 44.5 13.3 51.9 25.7 32.4 41.9 26.8 23.7 16.9 41.4 39.6 78.6 35.6 48.2 45.8 48.2 48.4 60.3 75.6 70.7 44.3 50.8 65.6 29.1 58.9 62.8 33.5 69.0 63.0 64.8 57.8 45.1 65.5 52.9 37.8 43.1 57.9 75.0 53.3 47.4 74.8 46.6 46.2 60.3 62.7 45.0 58.6 51.6 31.8 84.9 41.4 62.3 43.7 48.9 43.3 40.3 55.4 47.6 63.2 29.9 58.9 54.9 47.7 39.7 59.3 42.4 65.5 52.5 49.0 55.1 43.7 69.8 54.2 66.6 82.2 44.0 55.2 57.2 21.3 15.6 19.1 18.1 18.9 21.5 16.6 17.3 20.6 18.5 16.6 18.3 22.0 11.7 18.1 33.0 13.5 19.8 14.3 15.4 17.0 25.3 20.2 16.9 14.8 14.7 13.2 14.6 13.2 13.3 16.9 21.8 9.6 18.9 19.6 30.5 22.2 13.7 16.0 17.1 13.6 20.6 17.7 21.1 14.3 17.9 20.2 22.9 25.7 28.2 16.6 1.9 15.9 15.8 19.8 20.7 19.6 25.9 22.5 37.9 14.0 27.8 20.3 23.9 27.5 16.5 20.0 18.9 20.4 19.7 11.8 39.1 20.6 10.2 25.3 18.3 10.9 22.4 19.5 12.4 14.0 22.3 12.5 15.5 24.6 25.5 18.6 10.5 30.9 39.7 18.0 14.4 10.1 15.2 17.6 6.6 21.9 25.3 52.4 27.8 24.5 22.6 36.8 28.5 17.0 16.8 15.5 RAD51AP2 FLJ17540 ENSG00000214842 "RAD51 associated protein 2" Q09MP3 2 17510584-17518439 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 14 "testis: 9.4" "Cell type enriched" "Detected in some" 8 "Spermatocytes: 457.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "unprognostic (3.87e-2)" "unprognostic (3.31e-2)" "unprognostic (9.98e-2)" "unprognostic (3.12e-2)" "unprognostic (4.61e-1)" "unprognostic (3.51e-1)" "unprognostic (9.80e-2)" "unprognostic (4.84e-3)" "unprognostic (2.64e-1)" "unprognostic (1.92e-1)" "unprognostic (1.71e-1)" "unprognostic (6.26e-3)" "unprognostic (3.82e-2)" "unprognostic (1.62e-3)" "unprognostic (1.15e-1)" 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.2 0.0 0.0 0.2 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.6 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.6 0.2 0.0 0.1 0.2 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.7 0.2 0.5 1.5 0.9 1.2 0.1 0.7 2.8 0.9 0.0 0.2 0.0 2.1 0.0 0.0 6.0 0.0 0.0 12.8 0.0 0.1 0.2 0.0 0.0 8.0 0.0 0.0 0.2 2.0 0.0 0.0 0.1 0.0 1.7 0.1 0.0 4.1 0.7 0.0 0.0 0.2 5.7 0.9 0.0 0.0 0.0 0.0 0.6 0.0 0.5 0.3 0.1 0.1 0.4 0.1 1.1 0.0 0.1 0.2 0.2 26.3 0.1 0.4 457.6 51.7 0.6 0.6 0.0 0.0 0.5 1.6 0.9 RAD9B FLJ40346 ENSG00000151164 "RAD9 checkpoint clamp component B" Q6WBX8 12 110501655-110533556 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 13 "testis: 11.3" "Group enriched" "Detected in some" 21 "Spermatocytes: 91.5;Spermatogonia: 29.0" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 5 "basophil: 4.7" "Lineage enriched" "Detected in single" 5 "granulocytes: 4.7" "Cell line enhanced" "Detected in some" "JURKAT: 2.7;SiHa: 2.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040643 Approved NA NA "Cluster 34: Basophils - Unknown function" "Cluster 74: Testis - Spermatogenesis" "Cluster 32: U-937 - Innate immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA040643: AB_10805716" "unprognostic (2.32e-1)" "unprognostic (2.55e-5)" "unprognostic (4.76e-2)" "unprognostic (1.30e-3)" "unprognostic (2.93e-1)" "unprognostic (6.27e-3)" "unprognostic (5.44e-2)" "unprognostic (2.00e-1)" "unprognostic (1.56e-2)" "unprognostic (1.22e-1)" "unprognostic (5.92e-2)" "unprognostic (2.26e-1)" "unprognostic (2.68e-3)" "unprognostic (7.33e-2)" "unprognostic (1.99e-1)" "unprognostic (2.15e-2)" "unprognostic (1.80e-2)" 0.3 0.1 0.3 0.2 0.4 0.3 0.4 0.4 0.4 0.4 0.2 0.3 0.0 0.4 0.4 0.3 0.3 0.1 0.8 0.3 0.3 0.2 0.3 0.3 0.5 0.4 0.3 0.7 0.1 0.1 0.1 0.1 0.4 0.3 0.1 0.4 0.1 0.4 0.8 0.2 0.2 0.5 0.3 0.3 0.2 11.3 0.4 0.4 0.2 0.5 0.3 0.3 0.2 0.7 1.6 0.1 0.1 0.4 0.1 0.3 0.1 0.7 0.2 0.7 0.6 1.6 0.1 1.2 0.3 0.2 0.1 0.1 0.2 0.1 0.2 0.1 0.4 1.5 0.2 0.0 0.2 1.9 0.3 0.2 0.2 0.6 0.5 0.2 0.1 2.7 0.3 0.9 0.9 0.2 0.4 0.5 0.1 0.5 0.5 0.1 0.4 0.3 0.3 0.2 0.3 0.1 2.9 0.3 0.4 0.0 0.6 1.0 0.2 0.3 0.0 0.3 0.2 0.6 0.3 0.7 0.3 1.0 1.0 4.7 0.5 0.2 0.2 0.4 0.2 0.4 0.3 0.1 0.9 0.3 0.2 0.1 0.5 0.2 0.9 0.5 0.1 0.3 0.3 0.4 0.4 0.4 0.3 0.3 0.4 0.3 0.4 0.3 0.4 0.7 0.2 0.0 0.0 1.6 0.7 0.5 0.4 0.5 0.0 0.3 0.3 0.3 1.5 0.0 0.1 0.0 0.0 0.0 0.1 0.1 1.9 0.3 2.8 0.2 0.1 0.4 0.0 0.4 0.7 0.0 0.1 0.7 0.0 0.3 0.0 0.9 0.4 0.3 1.3 0.0 0.7 0.0 0.0 1.2 0.3 2.0 1.5 0.5 0.0 1.9 1.9 0.6 1.0 0.5 2.8 0.4 0.0 0.0 0.5 0.2 0.0 0.1 2.4 0.8 0.0 0.5 0.2 91.5 29.0 0.0 0.4 0.1 0.3 0.1 0.1 0.2 RAPH1 "ALS2CR18, ALS2CR9, KIAA1681" ENSG00000173166 "Ras association (RalGDS/AF-6) and pleckstrin homology domains 1" Q70E73 2 203394345-203535335 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 61.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 84.0;Hepatic stellate cells: 103.5;Microglial cells: 92.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016744, HPA020027" Approved Approved "Nuclear bodies,Plasma membrane,Cytosol" NA NA 69000000 "Cluster 7: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 44: Endometrium - Transcription" "Nuclear bodies, Plasma membrane" Cytosol "HPA016744: AB_1844781, HPA020027: AB_1844782" "unprognostic (9.78e-2)" "unprognostic (9.05e-2)" "unprognostic (7.17e-4)" "unprognostic (1.04e-1)" "unprognostic (1.58e-1)" "unprognostic (1.83e-1)" "unprognostic (8.32e-2)" "unprognostic (6.31e-2)" "unprognostic (1.39e-1)" "unprognostic (1.31e-1)" "unprognostic (1.24e-4)" "unprognostic (1.92e-1)" "unprognostic (1.40e-2)" "unprognostic (5.11e-2)" "unprognostic (2.30e-1)" "unprognostic (1.19e-2)" "unprognostic (2.79e-1)" 11.1 6.5 1.5 5.2 4.6 3.1 13.3 1.3 7.9 9.4 0.3 7.0 7.8 5.6 4.6 8.8 5.1 8.9 5.9 5.0 8.5 7.2 61.6 14.3 3.7 2.4 7.0 2.0 6.4 5.6 3.6 13.0 4.1 6.6 7.3 7.3 8.6 4.3 6.6 8.9 7.9 7.8 0.1 16.9 8.8 9.4 2.7 2.6 30.0 6.2 4.9 7.7 6.6 2.2 11.1 7.5 15.6 9.0 12.0 15.4 14.7 15.1 11.0 15.3 19.1 35.0 11.4 0.0 3.7 23.1 11.2 5.8 8.2 12.9 31.7 2.2 4.6 0.0 17.9 6.2 30.0 0.1 0.2 21.5 10.7 28.1 29.4 16.8 24.2 1.7 0.8 8.2 31.0 6.2 0.1 0.0 9.2 5.7 10.0 0.2 22.0 6.9 11.2 34.9 5.5 7.5 10.3 9.8 12.5 20.4 5.5 0.5 29.0 37.5 12.5 18.2 16.1 3.8 7.7 0.1 30.9 0.2 8.4 0.0 0.2 0.0 0.0 0.7 0.1 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.7 0.0 0.1 0.0 1.5 4.6 1.3 7.9 5.0 8.5 2.4 7.0 4.1 0.1 2.7 2.2 36.3 16.0 8.4 12.7 1.2 49.1 20.7 10.3 16.5 11.3 21.6 9.4 1.1 15.7 9.7 14.7 14.6 8.9 0.8 32.9 7.9 6.3 14.4 24.4 17.7 29.0 2.4 3.2 84.0 9.3 7.6 23.4 47.9 65.7 1.3 6.2 103.5 79.6 18.1 10.1 56.7 8.6 4.1 17.8 51.1 4.9 4.7 28.8 12.4 92.8 3.3 18.6 0.0 41.2 9.1 20.5 21.3 4.9 0.1 19.0 22.4 2.8 5.2 4.4 19.7 26.8 33.4 29.3 19.6 26.9 40.9 10.9 2.8 0.9 13.3 28.4 RB1CC1 "ATG17, Cc1, DRAGOU14, FIP200, KIAA0203, PPP1R131" ENSG00000023287 "RB1 inducible coiled-coil 1" Q8TDY2 8 52622458-52745843 "Predicted intracellular proteins" "Autophagy, Cell cycle, Transcription, Transcription regulation" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024391, HPA053049" Approved Supported "Nuclear membrane,Cytosol" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" Cytosol "Nuclear membrane" "HPA024391: AB_2671554, HPA053049: AB_2682025" "unprognostic (1.58e-2)" "unprognostic (7.51e-2)" "unprognostic (9.49e-2)" "prognostic unfavorable (1.61e-4)" "unprognostic (3.22e-1)" "unprognostic (4.21e-2)" "unprognostic (7.39e-2)" "unprognostic (1.38e-2)" "unprognostic (9.34e-2)" "unprognostic (1.21e-1)" "unprognostic (8.77e-3)" "unprognostic (2.07e-1)" "unprognostic (9.56e-3)" "unprognostic (7.67e-2)" "unprognostic (4.41e-1)" "unprognostic (8.00e-2)" "unprognostic (2.42e-1)" 17.6 15.0 37.2 11.8 30.4 52.3 17.0 26.5 40.2 15.2 16.4 13.7 12.9 17.4 13.0 16.9 12.1 13.8 24.1 27.2 23.9 17.1 21.5 14.9 13.3 29.9 25.6 20.1 16.8 22.2 8.0 15.5 24.1 15.5 11.3 20.3 16.2 12.2 38.9 15.0 14.2 15.0 23.0 14.3 14.5 34.7 33.1 22.2 17.7 32.1 12.9 14.3 11.1 43.5 23.8 20.8 25.2 22.1 27.4 31.0 14.4 17.7 36.1 18.4 22.8 14.6 26.3 17.4 29.0 26.2 46.4 31.0 31.4 16.5 34.5 13.1 27.4 29.7 20.8 20.2 33.7 10.7 16.0 29.1 33.4 18.3 49.6 38.2 25.2 26.8 35.8 27.4 22.6 15.6 27.2 15.7 24.9 22.4 10.3 13.7 12.1 17.7 16.9 18.5 24.0 25.0 18.4 20.9 39.8 29.3 23.8 19.3 29.9 17.5 24.2 27.8 15.7 26.8 24.8 17.0 27.6 18.2 20.0 47.9 12.9 24.6 11.6 12.2 11.8 12.3 9.7 11.9 12.6 9.5 11.9 11.0 40.3 14.2 17.1 6.3 14.1 11.9 37.2 30.4 26.5 40.2 27.2 23.9 29.9 25.6 24.1 23.0 33.1 43.5 83.8 195.5 121.7 73.8 66.3 88.3 60.2 32.0 51.2 82.0 45.5 39.5 163.8 20.0 57.4 18.4 68.8 27.0 74.2 45.4 9.8 52.4 61.9 103.6 112.7 66.0 44.2 117.7 104.0 49.3 26.3 78.2 36.2 143.5 25.9 78.1 36.8 44.5 23.6 87.5 123.2 31.9 30.5 44.5 41.4 49.8 77.3 60.5 42.7 76.8 67.6 33.0 64.9 106.1 104.2 63.5 43.3 73.4 86.1 99.0 47.2 27.0 115.3 57.3 46.0 132.2 76.9 238.8 132.7 59.4 91.9 60.5 66.2 68.6 27.7 88.2 RBM44 FLJ40411 ENSG00000177483 "RNA binding motif protein 44" Q6ZP01 2 237798389-237842808 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 31 "testis: 15.7" "Group enriched" "Detected in many" 4 "Spermatocytes: 104.7;Spermatogonia: 59.8" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 13 "basophil: 1.3" "Lineage enriched" "Detected in single" 13 "granulocytes: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA003298 Enhanced NA NA "Cluster 34: Basophils - Unknown function" "Cluster 36: Testis - Spermatogenesis" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA003298: AB_2284846" "unprognostic (1.29e-1)" "unprognostic (2.66e-1)" "unprognostic (5.92e-2)" "unprognostic (1.56e-1)" "unprognostic (8.47e-3)" "unprognostic (3.15e-2)" "unprognostic (2.41e-1)" "unprognostic (2.60e-1)" "unprognostic (1.83e-2)" "unprognostic (8.12e-2)" "unprognostic (4.10e-2)" "unprognostic (4.57e-2)" "unprognostic (5.01e-5)" "unprognostic (1.90e-1)" "unprognostic (4.27e-2)" "unprognostic (6.85e-3)" "unprognostic (7.89e-3)" 0.3 0.0 0.0 0.1 0.0 0.5 0.3 0.0 0.1 0.3 0.0 0.2 0.0 0.2 0.2 0.1 0.1 0.1 0.1 0.0 0.0 0.2 0.1 0.3 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.2 0.1 0.2 0.2 0.0 0.3 0.1 15.7 0.0 0.0 0.1 0.3 0.1 0.2 0.2 0.0 0.0 0.0 0.2 0.1 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.1 0.3 0.3 0.0 0.1 0.0 0.2 0.3 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.6 0.1 0.0 0.2 0.0 0.0 0.2 0.4 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.3 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 1.1 1.6 0.4 0.8 0.7 0.3 0.6 0.0 0.8 0.3 0.7 1.5 1.5 1.8 0.0 0.1 2.2 0.0 0.0 0.1 16.8 2.0 0.5 2.4 0.0 0.0 2.4 0.2 0.3 1.0 0.0 4.6 0.0 0.3 0.0 0.2 0.3 0.0 3.3 0.0 0.0 0.8 2.3 16.1 2.8 1.5 1.8 1.9 1.4 0.0 1.0 3.0 0.4 0.6 0.0 1.5 1.0 2.0 0.1 0.1 1.8 0.0 6.6 2.6 0.7 104.7 59.8 0.2 0.6 0.0 0.8 0.7 0.0 1.6 RGP1 KIAA0258 ENSG00000107185 "RGP1 homolog, RAB6A GEF complex partner 1" Q92546 9 35749287-35758585 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020414, HPA021085" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 40: Granulosa cells - Unknown function" Cytosol "Plasma membrane" "HPA020414: AB_1852289, HPA021085: AB_1852291" "unprognostic (2.10e-1)" "unprognostic (3.22e-2)" "unprognostic (1.03e-1)" "unprognostic (2.01e-2)" "unprognostic (3.35e-2)" "unprognostic (1.47e-1)" "prognostic unfavorable (7.09e-4)" "unprognostic (2.22e-1)" "unprognostic (5.42e-2)" "unprognostic (1.51e-3)" "unprognostic (1.81e-3)" "unprognostic (9.77e-2)" "prognostic favorable (8.55e-13)" "unprognostic (2.46e-2)" "unprognostic (1.68e-1)" "unprognostic (3.03e-3)" "unprognostic (1.18e-1)" 9.8 10.4 7.5 8.7 6.9 5.6 8.5 6.6 6.7 7.9 3.4 12.9 10.7 8.8 7.8 8.6 8.3 6.0 12.9 7.3 7.8 11.5 7.4 9.1 7.5 5.8 6.3 10.1 10.7 19.1 10.5 9.3 6.0 8.7 13.4 7.8 11.0 11.4 17.3 9.4 11.6 9.8 5.6 7.4 10.3 6.4 8.0 8.9 12.2 18.6 9.6 8.0 6.5 5.9 18.0 16.6 18.9 15.8 17.3 18.6 11.1 13.9 20.1 18.9 17.4 14.2 6.7 13.9 9.7 17.8 34.9 9.9 18.3 26.2 15.5 18.6 10.7 11.9 32.9 10.7 16.3 13.0 16.1 18.8 32.8 19.9 24.0 27.0 22.7 10.6 8.2 7.5 17.3 8.5 4.0 4.7 7.9 14.7 19.2 13.2 13.5 9.9 16.5 12.4 13.8 14.9 12.3 17.0 11.2 16.6 14.2 6.2 29.0 15.1 18.9 10.5 11.8 11.1 16.5 14.3 21.5 5.4 19.7 1.1 0.2 0.4 0.7 0.4 1.1 0.8 0.5 0.8 0.1 1.0 0.6 0.7 0.7 1.1 0.6 0.6 0.5 0.2 7.5 6.9 6.6 6.7 7.3 7.8 5.8 6.3 6.0 5.6 8.0 5.9 13.9 6.4 12.6 0.0 23.4 5.7 24.5 14.8 9.1 40.8 15.0 10.0 16.6 18.6 15.8 27.6 20.9 10.9 19.1 46.1 13.7 20.1 17.5 9.8 8.3 14.9 43.3 8.6 0.2 17.6 10.6 7.5 18.8 14.9 5.7 33.4 16.1 16.4 7.5 16.8 0.1 26.0 22.4 7.7 6.1 36.8 8.4 5.7 1.8 0.0 11.1 18.8 25.7 0.0 0.1 20.6 38.3 10.9 15.2 25.3 36.3 14.2 17.7 22.3 6.6 11.8 9.3 16.6 6.1 8.1 5.3 10.3 16.4 7.1 28.9 28.8 RNF17 "FLJ11045, Mmip-2, SPATA23, TDRD4" ENSG00000132972 "Ring finger protein 17" Q9BXT8 13 24764169-24879921 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "testis: 24.3" "Group enriched" "Detected in some" 7 "Early spermatids: 22.2;Late spermatids: 27.6;Spermatocytes: 67.0;Spermatogonia: 24.3" "Cancer enriched" "Detected in single" 41 "testis cancer: 4.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 13 "olfactory bulb: 1.4" "HPA039699, HPA040111" Approved NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA039699: AB_10795254, HPA040111: AB_10795414" "unprognostic (2.57e-1)" "unprognostic (1.87e-2)" "unprognostic (1.37e-1)" "unprognostic (4.44e-1)" "unprognostic (4.26e-1)" "unprognostic (3.21e-2)" "unprognostic (1.59e-1)" "unprognostic (1.69e-1)" "unprognostic (8.61e-2)" "unprognostic (5.04e-1)" "unprognostic (3.12e-1)" "unprognostic (8.32e-2)" "unprognostic (1.22e-1)" 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.6 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 24.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 1.3 0.0 0.0 0.1 3.8 0.0 0.0 0.1 0.8 1.2 0.0 0.2 0.0 0.0 1.9 0.0 0.0 0.0 0.0 22.2 0.0 0.1 0.2 0.0 0.0 2.1 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.9 0.0 0.0 0.0 0.0 27.6 0.9 0.0 0.0 1.0 0.0 0.0 0.0 1.5 1.5 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 67.0 24.3 0.0 0.0 1.0 0.0 0.0 0.0 0.1 RNF34 "FLJ21786, RIF, RIFF" ENSG00000170633 "Ring finger protein 34" Q969K3 12 121400041-121430623 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 134.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074151 Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "Nuclear bodies" "HPA074151: AB_2686668" "unprognostic (3.54e-1)" "unprognostic (4.83e-2)" "unprognostic (1.90e-1)" "unprognostic (6.10e-2)" "unprognostic (9.92e-2)" "unprognostic (2.55e-2)" "prognostic unfavorable (6.72e-8)" "unprognostic (3.39e-1)" "unprognostic (9.99e-2)" "unprognostic (1.60e-2)" "unprognostic (5.87e-3)" "unprognostic (2.80e-2)" "prognostic unfavorable (4.63e-4)" "unprognostic (1.09e-1)" "unprognostic (3.55e-1)" "unprognostic (5.55e-3)" "prognostic favorable (3.02e-4)" 13.7 10.8 25.5 23.6 29.7 13.4 13.4 31.6 32.2 11.6 21.8 19.2 19.5 13.7 13.5 14.9 12.5 17.3 18.4 26.8 28.6 11.3 13.0 12.9 34.3 26.0 26.6 14.7 13.8 13.3 13.7 11.5 26.7 10.5 15.6 19.0 13.9 13.5 59.5 15.7 18.3 16.7 24.7 23.3 18.4 24.6 26.6 26.8 13.9 36.8 26.4 19.0 11.9 32.7 45.4 53.8 34.7 36.3 26.8 24.5 43.2 47.5 42.2 46.3 35.3 67.3 16.9 64.9 35.3 51.3 24.6 31.8 52.6 29.8 41.0 95.3 30.8 75.4 37.7 62.5 32.1 65.7 50.4 21.9 39.6 40.2 34.7 26.4 49.3 37.9 58.0 29.3 46.0 35.7 57.5 95.7 44.5 26.6 48.4 54.0 45.1 38.1 32.0 53.2 50.7 33.0 59.4 21.8 36.6 31.6 38.0 49.1 39.5 39.5 28.4 34.6 37.8 51.2 92.8 70.5 28.2 45.4 40.6 83.7 42.1 91.2 72.4 48.4 74.1 77.1 83.2 76.8 40.4 65.0 71.1 71.1 65.2 76.2 53.3 34.3 106.3 68.3 25.5 29.7 31.6 32.2 26.8 28.6 26.0 26.6 26.7 24.7 26.6 32.7 14.5 16.0 16.2 15.3 22.9 17.5 18.7 23.4 13.6 13.9 16.5 13.2 22.0 27.1 18.9 9.2 4.2 26.1 30.9 19.0 37.2 32.7 23.5 13.7 15.3 17.3 40.8 24.8 34.3 27.3 38.8 16.1 15.8 13.9 17.7 19.0 17.2 11.2 21.2 13.5 32.7 15.8 30.5 18.0 14.9 10.7 17.1 14.0 17.8 13.1 35.0 23.6 46.4 9.5 45.5 26.2 17.2 18.0 27.9 17.0 20.5 19.9 18.7 21.4 19.7 11.1 25.0 134.0 73.9 15.3 16.1 24.2 34.3 18.5 21.2 25.7 RPA2 ENSG00000117748 "Replication protein A2" P15927 1 27891524-27914746 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, DNA replication" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 162.3;Spermatogonia: 183.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016538, HPA026306, HPA026309" Supported Enhanced "Nucleoplasm,Nuclear bodies" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Nucleoplasm, Nuclear bodies" "CAB016538: AB_670974, HPA026306: AB_10598913, HPA026309: AB_10601572" "unprognostic (2.59e-1)" "prognostic favorable (4.33e-4)" "unprognostic (8.98e-2)" "unprognostic (6.89e-2)" "unprognostic (1.04e-1)" "prognostic favorable (8.12e-4)" "unprognostic (4.29e-3)" "unprognostic (2.03e-2)" "unprognostic (8.62e-3)" "unprognostic (1.68e-1)" "unprognostic (1.58e-2)" "unprognostic (2.31e-1)" "unprognostic (3.59e-2)" "unprognostic (9.13e-2)" "unprognostic (2.30e-1)" "unprognostic (2.18e-3)" "unprognostic (2.82e-2)" 28.4 25.0 33.3 39.7 35.1 40.7 43.8 33.4 42.4 32.0 37.4 26.6 18.5 33.7 43.4 32.3 49.1 30.6 39.2 34.5 36.1 32.4 31.8 28.7 75.1 33.7 33.2 52.0 21.0 40.7 31.3 30.2 33.9 28.7 30.2 43.8 24.0 31.3 72.3 40.3 26.1 30.7 36.7 42.3 25.6 63.7 34.0 53.4 52.9 63.2 67.6 30.3 24.9 36.7 60.9 57.4 86.4 68.5 59.3 52.8 57.2 106.1 70.3 130.0 113.5 80.2 72.7 148.9 69.4 41.1 48.4 55.8 126.5 60.3 122.4 121.0 126.0 174.3 73.0 71.3 30.9 229.7 115.1 24.6 33.2 123.8 62.3 40.3 59.1 133.1 196.2 127.1 75.7 63.6 163.9 105.1 181.7 115.1 122.0 115.0 128.7 74.2 49.1 65.2 78.3 75.8 123.3 47.3 100.7 68.1 50.9 71.8 36.6 32.2 73.0 186.2 76.3 105.8 251.0 135.8 81.4 213.5 64.3 322.3 97.4 290.0 279.7 80.0 304.4 272.5 252.9 257.4 112.1 232.0 287.4 282.7 100.1 294.1 106.5 172.3 255.5 435.5 33.3 35.1 33.4 42.4 34.5 36.1 33.7 33.2 33.9 36.7 34.0 36.7 26.5 22.4 15.7 10.4 64.0 21.0 28.5 47.1 16.5 28.4 25.7 27.8 29.0 24.3 30.4 22.0 2.1 95.2 77.8 10.1 35.2 35.0 49.0 14.6 18.8 27.9 13.8 39.1 8.8 20.6 67.3 34.8 7.1 15.1 60.9 33.3 26.4 16.6 51.9 8.4 8.4 14.0 71.2 31.5 27.6 22.6 41.3 34.1 37.4 7.5 86.7 100.0 95.8 9.5 14.3 29.5 10.4 46.3 32.6 19.3 11.2 23.6 28.8 34.5 32.9 48.0 24.7 162.3 183.5 20.6 22.4 55.7 59.9 33.9 19.3 20.1 RRM1 ENSG00000167325 "Ribonucleotide reductase catalytic subunit M1" P23921 11 4094707-4138932 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA replication" "Allosteric enzyme, Oxidoreductase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 102.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022093, HPA057265, HPA064297" Enhanced Supported Cytosol NA Yes 140000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "CAB022093: , HPA057265: AB_2683386, HPA064297: AB_2685236" "unprognostic (4.47e-2)" "unprognostic (1.73e-2)" "unprognostic (1.99e-3)" "unprognostic (3.65e-1)" "unprognostic (2.83e-1)" "unprognostic (2.19e-1)" "prognostic unfavorable (1.53e-4)" "unprognostic (1.31e-2)" "unprognostic (3.43e-2)" "unprognostic (6.90e-2)" "unprognostic (1.06e-3)" "unprognostic (4.21e-2)" "unprognostic (6.88e-3)" "unprognostic (9.20e-3)" "unprognostic (6.16e-2)" "unprognostic (8.41e-2)" "unprognostic (9.93e-3)" 16.6 21.2 5.1 24.8 5.3 32.8 22.7 7.1 6.1 16.9 4.7 25.7 19.3 16.2 10.1 26.5 15.5 11.8 16.4 5.1 5.7 13.4 18.4 12.8 34.4 6.1 5.5 16.4 14.6 24.7 7.1 20.4 6.6 18.5 29.4 23.6 14.7 16.0 30.3 36.1 20.2 20.1 6.2 13.0 17.6 17.9 5.1 56.7 15.6 30.0 45.2 15.6 18.9 6.2 221.6 117.8 188.4 110.0 28.4 56.2 73.0 198.0 98.2 220.7 225.9 106.8 163.8 237.4 47.0 100.1 95.9 173.0 176.9 143.2 259.3 117.3 187.9 121.0 159.8 83.1 11.2 208.9 84.6 26.6 37.8 121.7 86.4 48.3 107.8 140.1 161.1 107.3 186.8 99.6 246.7 41.9 118.2 152.2 119.2 196.1 147.0 84.3 59.4 61.8 159.8 88.1 175.1 104.8 30.0 75.8 102.8 71.4 62.3 203.4 106.0 206.9 147.4 70.3 103.5 252.5 114.1 137.6 130.3 8.3 4.0 4.5 11.3 11.2 21.1 9.2 22.3 16.6 7.3 5.2 17.2 15.0 0.0 10.5 15.6 4.4 41.7 10.3 5.1 5.3 7.1 6.1 5.1 5.7 6.1 5.5 6.6 6.2 5.1 6.2 12.4 19.2 14.4 4.9 17.0 33.4 26.8 31.0 17.6 15.6 15.1 14.4 33.5 14.3 24.7 18.4 6.2 62.8 14.9 13.3 7.9 25.6 69.9 11.5 14.5 15.7 18.0 81.2 11.2 22.2 62.5 22.0 20.4 13.9 7.0 27.3 10.8 15.0 28.3 18.5 12.0 25.0 16.2 11.7 10.3 83.9 13.1 13.9 10.6 6.5 10.7 24.0 5.2 12.1 11.9 15.8 10.4 16.6 31.3 10.1 12.5 8.4 15.5 22.7 13.1 19.5 27.1 102.8 63.1 36.5 29.0 39.7 23.2 18.1 34.3 20.6 RRM2 "C2orf48, FLJ25102" ENSG00000171848 "Ribonucleotide reductase regulatory subunit M2" P31350 2 10120698-10211725 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "DNA replication" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 44.2;esophagus: 18.4;intestine: 19.7;lymphoid tissue: 58.1" "Group enriched" "Detected in many" 4 "Erythroid cells: 214.0;Extravillous trophoblasts: 254.1;Plasma cells: 248.0" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056994 Enhanced Supported Cytosol Yes Yes 13000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA056994: AB_2683304" "unprognostic (2.10e-2)" "unprognostic (1.62e-1)" "unprognostic (6.40e-3)" "unprognostic (4.42e-3)" "unprognostic (5.70e-2)" "unprognostic (1.69e-1)" "prognostic unfavorable (1.39e-5)" "unprognostic (1.04e-3)" "unprognostic (6.67e-3)" "unprognostic (4.53e-2)" "prognostic unfavorable (1.62e-4)" "unprognostic (5.11e-3)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.05e-2)" "unprognostic (2.24e-1)" "unprognostic (1.38e-1)" "unprognostic (2.09e-2)" 1.5 1.3 0.3 12.4 0.3 44.2 2.9 0.5 0.4 3.0 1.9 14.2 9.4 2.2 0.7 18.4 0.8 1.1 0.5 0.3 0.3 0.9 3.2 2.4 35.5 0.4 0.4 0.3 1.1 0.3 0.2 4.6 0.4 0.9 19.7 0.2 2.1 0.5 0.1 3.7 7.5 6.1 0.3 11.1 6.0 2.9 0.8 58.1 0.9 0.1 37.6 6.0 4.6 0.5 110.2 25.0 127.1 49.9 7.4 22.5 116.8 209.2 128.6 170.2 187.9 70.8 59.1 114.4 9.5 88.6 151.1 55.0 188.0 136.6 198.0 210.7 41.8 146.3 52.1 105.1 0.8 146.7 87.4 8.1 3.4 234.6 16.2 27.7 103.3 110.4 63.4 328.6 214.3 57.1 167.3 90.9 83.0 133.3 103.6 87.6 187.0 67.8 87.1 62.7 67.7 56.2 198.0 116.6 17.3 51.8 69.2 31.4 57.6 93.1 125.1 66.9 289.6 212.1 184.9 195.9 51.0 134.4 107.7 0.3 0.1 0.1 1.2 0.0 0.0 0.1 0.3 0.8 0.1 0.1 0.1 0.4 0.4 0.8 0.0 0.1 0.2 0.2 0.3 0.3 0.5 0.4 0.3 0.3 0.4 0.4 0.4 0.3 0.8 0.5 0.2 3.2 1.5 0.0 25.0 10.5 3.0 9.2 1.2 0.0 3.9 4.4 1.4 1.5 2.3 0.0 0.0 42.3 5.6 12.9 1.9 1.2 3.9 2.2 3.5 4.2 0.0 214.0 0.1 0.0 254.1 11.2 11.7 3.6 5.7 12.2 3.9 3.7 47.9 0.0 0.0 26.9 2.0 7.2 8.8 6.8 0.3 5.0 0.0 1.0 0.0 0.0 7.2 0.0 0.0 0.5 0.3 0.4 248.0 1.5 2.4 2.1 4.6 0.0 0.0 0.2 14.6 22.9 34.0 51.5 1.6 48.7 11.9 1.2 36.7 5.6 RSBN1 "FLJ11220, ROSBIN" ENSG00000081019 "Round spermatid basic protein 1" Q5VWQ0 1 113761832-113812476 "Predicted intracellular proteins" "Chromatin regulator, Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042124, HPA049484" Approved Supported "Nucleoplasm,Nuclear bodies,Vesicles" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 14: REH - Unknown function" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "Nuclear bodies, Vesicles" "HPA042124: AB_10794644, HPA049484: AB_2680787" "unprognostic (3.26e-2)" "unprognostic (1.32e-1)" "unprognostic (1.15e-3)" "unprognostic (2.13e-1)" "unprognostic (3.66e-2)" "unprognostic (2.30e-2)" "unprognostic (5.06e-2)" "unprognostic (6.60e-2)" "unprognostic (1.06e-1)" "unprognostic (1.97e-2)" "unprognostic (1.56e-1)" "unprognostic (3.96e-1)" "unprognostic (1.51e-2)" "unprognostic (4.67e-2)" "unprognostic (1.43e-1)" "unprognostic (1.24e-1)" "unprognostic (1.15e-3)" 6.4 6.0 4.6 7.7 4.7 34.4 8.2 12.7 6.1 7.9 2.8 8.4 6.2 10.3 6.5 7.3 7.9 6.4 5.2 4.2 5.3 8.0 6.4 7.5 10.6 3.1 3.7 14.2 11.0 11.0 5.1 6.6 3.2 7.9 8.6 13.7 6.8 6.9 8.0 7.5 7.5 7.0 3.9 9.2 6.8 10.7 4.3 12.3 9.0 7.9 10.5 6.4 5.5 5.2 14.6 4.1 13.7 8.2 8.0 9.2 6.6 5.1 10.9 10.1 10.5 4.9 4.3 12.7 7.9 6.3 4.6 6.2 9.8 6.2 16.4 12.3 7.1 9.6 4.4 5.6 6.0 18.1 9.9 7.0 6.7 8.6 8.2 8.6 8.1 14.0 14.7 7.7 7.5 14.9 14.7 10.8 11.6 4.6 6.9 26.3 13.4 6.6 6.0 6.2 13.8 11.0 9.7 9.4 8.7 6.8 4.5 12.1 9.7 9.0 9.7 13.5 8.3 10.3 8.2 15.9 9.3 10.9 15.4 53.3 14.5 25.6 29.1 11.7 29.3 32.2 31.2 27.2 12.8 33.1 31.9 26.2 29.0 25.4 13.4 27.3 30.6 12.6 4.6 4.7 12.7 6.1 4.2 5.3 3.1 3.7 3.2 3.9 4.3 5.2 37.4 35.3 20.1 16.0 52.7 74.7 39.2 26.9 45.5 90.0 35.0 46.7 21.5 24.3 29.6 25.8 66.7 26.3 68.0 55.5 19.6 22.3 25.6 26.2 39.4 38.9 49.4 37.5 34.3 26.0 24.1 41.5 17.9 28.8 36.1 23.4 32.5 18.7 19.2 97.6 34.2 58.5 28.5 26.3 37.7 9.0 50.4 25.7 40.9 30.9 35.0 56.7 62.8 33.7 34.6 21.2 54.0 49.7 34.7 44.3 40.2 17.2 27.8 106.5 39.5 43.8 54.9 96.8 37.0 34.3 65.1 31.5 84.8 24.2 52.7 37.8 RUNDC1 DKFZp761H0421 ENSG00000198863 "RUN domain containing 1" Q96C34 17 42980565-42993690 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023726 Uncertain Approved "Nuclear speckles,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 11: Alveolar cells - Smell perception" "Nuclear speckles" Cytosol "HPA023726: AB_2184078" "unprognostic (4.24e-2)" "unprognostic (1.26e-1)" "unprognostic (9.39e-2)" "prognostic favorable (6.93e-5)" "unprognostic (9.78e-2)" "unprognostic (1.22e-1)" "unprognostic (6.40e-2)" "unprognostic (1.71e-1)" "unprognostic (2.59e-1)" "unprognostic (2.91e-2)" "unprognostic (3.84e-2)" "unprognostic (1.22e-1)" "unprognostic (1.53e-3)" "unprognostic (2.87e-3)" "unprognostic (1.25e-1)" "unprognostic (1.12e-2)" "unprognostic (4.77e-3)" 5.5 8.0 8.7 6.6 11.0 6.8 10.0 6.5 11.0 8.6 9.7 9.4 6.5 8.7 12.1 6.6 14.5 6.1 7.3 9.6 8.8 8.4 5.0 6.9 7.2 6.3 6.8 5.0 7.9 12.0 9.4 4.8 6.2 12.1 7.6 8.5 7.5 8.5 11.6 7.1 7.8 8.6 5.8 8.1 10.1 6.8 7.9 6.7 10.2 9.0 7.7 8.4 6.2 8.2 12.9 22.1 8.8 11.9 14.7 8.8 9.3 12.2 12.6 17.1 12.7 14.0 7.2 8.6 10.7 12.1 11.6 15.8 11.3 12.3 18.9 9.7 17.7 5.8 12.8 13.5 9.4 12.6 11.9 6.6 14.7 15.1 10.0 13.6 9.2 9.3 11.2 5.3 9.9 9.3 15.6 8.9 9.9 18.3 13.8 11.2 12.3 8.6 14.3 17.0 12.8 11.8 9.6 9.0 10.2 12.9 17.5 13.9 7.6 15.4 9.6 9.2 14.7 12.6 13.1 7.5 11.0 6.6 9.8 4.7 2.3 7.9 1.3 3.8 1.7 3.7 1.6 1.1 1.8 3.7 1.6 1.7 5.4 1.1 2.8 5.6 2.0 1.0 8.7 11.0 6.5 11.0 9.6 8.8 6.3 6.8 6.2 5.8 7.9 8.2 5.3 44.8 38.4 6.5 18.7 15.0 11.0 5.8 9.1 18.9 19.2 9.8 13.7 22.8 17.2 5.5 22.9 9.8 19.1 28.7 21.5 11.8 8.1 26.4 9.6 10.3 19.2 5.7 13.8 9.8 7.3 8.6 20.4 19.5 11.4 8.4 10.4 6.1 8.4 38.7 11.0 16.9 6.1 10.5 14.7 4.5 9.9 9.5 3.6 7.5 14.3 14.3 12.3 5.0 6.2 10.1 16.4 14.3 11.7 16.6 15.1 12.8 24.7 33.2 19.7 8.5 9.6 22.9 14.9 7.2 14.6 5.5 13.9 10.4 17.8 17.0 SAP30 ENSG00000164105 "Sin3A associated protein 30" O75446 4 173369969-173377532 "Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Kupffer cells: 77.2;Macrophages: 77.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Karpas-707: 181.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022627, HPA059012" Enhanced Supported Nucleoplasm "Intracellular and membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm "CAB022627: , HPA059012: AB_2683880" "unprognostic (1.53e-1)" "unprognostic (3.67e-2)" "unprognostic (3.26e-1)" "unprognostic (1.39e-1)" "unprognostic (5.83e-2)" "unprognostic (8.71e-2)" "prognostic unfavorable (1.24e-6)" "unprognostic (4.95e-2)" "unprognostic (7.23e-2)" "unprognostic (3.93e-2)" "unprognostic (4.48e-1)" "unprognostic (1.93e-2)" "prognostic unfavorable (1.54e-7)" "unprognostic (3.97e-1)" "unprognostic (5.70e-2)" "unprognostic (1.30e-1)" "unprognostic (2.21e-1)" 17.4 12.9 17.4 13.3 19.7 23.4 12.8 18.4 21.6 13.9 16.1 25.6 9.5 13.2 9.6 9.9 16.9 8.6 20.4 17.0 18.2 6.2 9.0 12.8 8.0 19.3 18.2 14.6 7.3 4.5 8.1 7.1 19.2 11.4 7.0 16.3 11.6 9.7 10.5 8.5 12.5 12.4 18.7 15.7 18.4 24.7 17.6 10.3 10.6 7.4 6.6 19.5 12.6 25.3 49.0 16.3 46.3 45.2 29.0 17.9 10.1 22.5 19.3 24.7 30.4 7.0 19.4 43.9 10.3 26.3 31.1 12.0 37.8 19.1 18.9 49.6 35.9 58.7 39.6 20.0 27.5 34.0 35.9 29.8 9.2 21.1 21.2 34.7 29.3 31.5 30.8 181.4 32.2 20.9 48.4 38.0 20.5 21.7 31.3 38.9 16.5 31.6 15.1 7.8 37.5 79.1 31.8 31.9 14.9 11.8 13.5 20.0 29.1 17.6 23.9 41.4 52.8 101.5 39.1 41.8 56.8 81.6 51.2 0.4 1.3 0.0 0.6 0.7 0.2 0.1 0.3 0.4 1.0 0.2 0.0 0.2 0.5 0.0 0.4 0.0 0.4 0.2 17.4 19.7 18.4 21.6 17.0 18.2 19.3 18.2 19.2 18.7 17.6 25.3 42.1 0.0 2.3 11.1 7.2 51.7 6.6 3.9 16.5 26.2 25.5 29.3 28.9 4.3 3.7 7.3 22.9 2.1 22.5 4.8 0.0 2.2 23.1 23.6 34.3 27.3 19.7 20.2 12.5 3.5 9.3 19.9 19.4 7.4 7.0 13.5 14.6 9.0 9.3 25.2 14.6 10.5 0.0 77.2 13.8 6.2 10.2 77.0 33.8 3.7 15.2 57.7 2.1 7.1 15.4 2.4 2.7 6.4 17.6 8.6 6.4 6.2 9.9 46.3 52.6 12.5 31.7 63.7 15.2 16.1 53.0 1.2 27.0 12.3 11.1 4.1 SASS6 "DKFZp761A078, FLJ22097, SAS-6, SAS6" ENSG00000156876 "SAS-6 centriolar assembly protein" Q6UVJ0 1 100083563-100132955 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Spermatocytes: 77.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "basophil: 3.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028187 Uncertain NA NA "Cluster 34: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "HPA028187: AB_10602220" "unprognostic (1.57e-1)" "unprognostic (2.52e-1)" "unprognostic (3.07e-2)" "unprognostic (2.06e-2)" "unprognostic (1.31e-1)" "unprognostic (3.02e-3)" "unprognostic (1.21e-4)" "unprognostic (1.27e-1)" "unprognostic (8.43e-3)" "unprognostic (4.73e-2)" "unprognostic (6.56e-2)" "unprognostic (3.71e-2)" "unprognostic (7.76e-8)" "unprognostic (1.19e-2)" "unprognostic (2.25e-1)" "unprognostic (1.20e-1)" "unprognostic (2.54e-1)" 1.3 1.2 1.0 2.9 1.2 6.0 2.8 1.6 1.5 1.6 0.8 2.2 2.8 2.0 2.2 2.1 1.4 1.0 1.0 0.8 1.0 1.0 1.4 1.3 4.2 1.1 1.2 1.8 1.4 3.9 1.6 2.0 1.1 2.1 3.0 5.7 1.8 1.5 1.3 2.1 2.2 1.8 1.1 2.1 2.1 6.7 1.0 4.3 1.5 0.9 3.6 1.4 1.6 1.3 17.0 5.2 13.1 11.5 1.5 2.6 19.3 10.7 4.7 13.5 15.6 9.0 8.5 18.5 8.0 3.7 8.0 14.8 18.0 6.5 18.6 8.9 17.8 16.2 10.9 11.3 0.9 26.8 14.5 1.3 2.8 11.4 9.0 2.7 7.3 12.2 25.8 17.6 6.7 4.8 22.2 12.9 17.5 11.1 10.7 16.1 25.9 9.4 6.5 8.1 9.5 14.0 9.9 17.0 8.7 9.4 8.6 15.9 3.8 9.5 11.6 10.9 14.9 7.4 18.5 24.6 7.7 17.7 5.3 3.9 0.1 1.0 0.7 0.6 0.9 1.6 0.8 0.7 0.5 0.7 0.7 0.6 0.7 0.6 0.5 0.2 0.9 0.3 1.0 1.2 1.6 1.5 0.8 1.0 1.1 1.2 1.1 1.1 1.0 1.3 7.2 0.0 2.3 8.5 12.8 4.0 2.8 7.1 6.8 19.4 8.4 9.4 2.9 7.2 5.9 1.8 16.7 13.6 13.5 2.4 1.9 7.5 15.7 7.4 5.8 5.8 4.2 33.2 7.6 5.6 17.3 7.0 7.1 5.4 5.7 15.0 6.8 3.1 9.1 8.4 9.6 4.8 14.2 8.4 4.7 6.2 8.1 5.8 1.8 5.6 6.1 13.3 20.6 5.0 16.1 6.2 2.7 10.9 19.7 4.5 2.2 4.3 4.9 23.0 0.0 12.6 5.9 77.4 36.0 11.9 4.1 5.1 7.9 4.0 8.8 2.1 SDR42E1 HSPC105 ENSG00000184860 "Short chain dehydrogenase/reductase family 42E, member 1" Q8WUS8 16 81988855-82011481 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "skin 1: 9.2" "Cell type enhanced" "Detected in many" "Ductal cells: 10.0;Ionocytes: 10.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 2.3;NK-cells: 2.0;T-cells: 2.2" "Cell line enhanced" "Detected in some" "HaCaT: 9.5;hTCEpi: 12.1;MCF7: 8.3;RT4: 20.6;SCLC-21H: 8.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014388 Uncertain NA NA "Cluster 37: B-cells - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 15: RT4 - Unknown function" "Cluster 1: Pancreatic cells - Digestion" "HPA014388: AB_1851226" "unprognostic (2.09e-1)" "unprognostic (4.90e-1)" "unprognostic (9.52e-3)" "unprognostic (3.81e-1)" "unprognostic (3.46e-1)" "unprognostic (1.14e-2)" "unprognostic (1.38e-1)" "unprognostic (2.91e-2)" "unprognostic (1.60e-1)" "unprognostic (4.51e-2)" "unprognostic (3.96e-2)" "unprognostic (4.93e-4)" "unprognostic (4.90e-7)" "unprognostic (2.18e-1)" "unprognostic (1.82e-1)" "unprognostic (3.21e-2)" "unprognostic (8.27e-2)" 0.5 0.1 0.0 0.9 0.1 0.4 4.4 0.0 0.1 1.2 0.1 2.4 5.6 1.3 1.9 3.6 1.7 1.1 0.6 0.0 0.2 1.9 1.8 1.6 1.3 0.1 0.1 0.3 3.2 2.1 1.3 0.3 0.1 1.7 1.7 0.0 3.1 0.9 0.0 9.2 4.7 1.1 0.0 0.8 2.6 1.1 0.2 1.6 1.9 0.0 2.4 2.3 2.4 0.0 3.7 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 4.9 0.0 1.8 0.0 0.4 9.5 0.0 6.5 0.0 0.0 0.6 0.0 1.7 0.0 0.3 0.0 0.0 0.3 12.1 1.5 5.9 0.0 0.0 0.0 1.6 0.0 0.8 8.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.8 2.5 20.6 8.2 0.0 0.2 4.3 0.0 0.2 0.1 0.0 0.2 0.0 4.3 0.0 0.0 4.0 5.9 0.4 0.0 0.0 0.0 0.0 0.0 0.4 0.8 0.0 1.1 2.3 0.7 1.2 0.1 1.0 2.2 1.6 0.0 2.0 0.0 0.1 1.5 0.9 0.0 0.1 0.0 0.1 0.0 0.2 0.1 0.1 0.1 0.0 0.2 0.0 1.0 0.0 1.1 0.0 2.7 5.9 3.5 6.1 6.2 0.0 5.8 3.9 2.6 7.2 3.3 1.8 0.0 0.6 1.1 2.7 3.9 10.0 1.3 2.8 0.7 0.5 2.4 0.4 0.0 7.5 0.2 0.4 1.1 3.2 0.0 0.4 0.0 3.7 0.0 0.0 0.0 6.0 10.2 0.0 0.3 2.0 0.0 0.2 1.8 0.0 0.0 0.0 1.0 0.0 0.1 6.3 4.5 0.0 1.1 3.8 9.7 2.9 3.6 0.0 0.0 0.0 0.5 8.4 6.2 5.6 9.1 0.3 1.2 0.1 4.1 4.4 SEC16A "KIAA0310, p250, Sec16L" ENSG00000148396 "SEC16 homolog A, endoplasmic reticulum export factor" O15027 9 136440096-136483759 "Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005684 Supported Supported "Endoplasmic reticulum,Golgi apparatus" NA NA 48000 "Cluster 27: Non-specific - Gene expression" "Cluster 29: Non-specific - Vesicular transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 27: Mucus-secreting cells - Mucin production" "Golgi apparatus" "Endoplasmic reticulum" "HPA005684: AB_1079189" "unprognostic (1.24e-3)" "unprognostic (2.07e-1)" "unprognostic (2.02e-1)" "prognostic favorable (1.30e-6)" "unprognostic (1.97e-1)" "unprognostic (1.72e-1)" "unprognostic (1.67e-1)" "unprognostic (3.84e-2)" "unprognostic (3.48e-1)" "unprognostic (5.30e-2)" "unprognostic (1.38e-3)" "unprognostic (4.75e-1)" "prognostic favorable (4.47e-4)" "unprognostic (5.57e-3)" "unprognostic (2.64e-1)" "unprognostic (2.47e-2)" "unprognostic (1.41e-1)" 16.8 18.2 6.4 16.6 6.7 35.3 17.1 8.0 9.4 16.6 19.3 17.3 14.9 17.9 9.0 17.9 16.4 12.4 14.5 7.0 5.2 14.3 37.9 19.4 16.9 4.4 4.9 16.2 29.2 14.0 24.3 10.8 3.5 18.7 10.5 9.2 25.8 13.1 23.5 19.7 19.1 10.7 2.4 20.7 27.2 17.6 5.2 17.4 15.3 11.9 12.3 15.9 14.5 5.0 26.5 57.7 28.5 47.2 29.6 30.3 33.6 32.1 27.9 23.4 17.8 41.9 22.1 26.4 22.1 39.2 28.8 71.3 31.8 46.2 12.7 56.2 20.7 26.9 55.1 33.7 28.6 46.2 45.8 32.8 32.5 32.7 38.1 18.9 32.2 34.5 34.1 35.6 25.0 114.3 31.2 24.9 25.1 79.0 40.4 44.3 35.2 45.0 23.8 35.0 40.0 26.6 41.6 62.2 19.8 13.8 63.6 35.9 47.0 37.6 28.1 30.8 25.2 16.9 27.7 33.4 29.2 20.6 38.3 1.7 2.8 1.2 2.5 3.1 2.7 2.3 2.6 3.0 1.6 1.4 1.6 2.8 2.0 1.5 3.4 2.6 1.9 2.4 6.4 6.7 8.0 9.4 7.0 5.2 4.4 4.9 3.5 2.4 5.2 5.0 20.0 25.6 41.7 16.6 16.4 24.9 15.3 18.4 10.8 20.2 38.7 30.6 11.5 12.8 23.6 12.9 25.0 8.1 17.5 30.1 7.9 14.2 5.1 26.9 19.5 18.2 40.7 12.0 27.4 16.4 11.8 16.0 46.9 38.2 23.5 25.4 17.9 62.2 16.5 33.7 19.2 65.5 20.3 23.4 19.5 6.0 13.1 22.3 14.2 17.8 19.5 13.0 11.3 9.5 14.7 22.8 14.7 16.6 25.1 26.3 22.3 10.1 34.7 17.1 13.1 20.5 16.6 24.4 16.1 17.2 26.9 15.1 17.8 15.8 22.8 22.1 SETX "ALS4, AOA2, KIAA0625, SCAR1, Sen1" ENSG00000107290 Senataxin Q7Z333 9 132261356-132354986 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Differentiation, DNA damage, DNA recombination, DNA repair, Neurogenesis, Spermatogenesis" "Helicase, Hydrolase" "Amyotrophic lateral sclerosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024105, HPA057269" Approved Supported "Nucleoplasm,Cytokinetic bridge" Yes No "Cluster 6: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm "Cytokinetic bridge" "HPA024105: AB_2671437, HPA057269: AB_2683389" "unprognostic (2.16e-1)" "unprognostic (5.77e-2)" "unprognostic (3.23e-1)" "unprognostic (2.03e-1)" "unprognostic (9.99e-2)" "unprognostic (2.14e-2)" "unprognostic (4.86e-2)" "unprognostic (1.64e-2)" "unprognostic (2.06e-2)" "unprognostic (1.38e-2)" "unprognostic (2.36e-1)" "unprognostic (3.32e-1)" "unprognostic (6.76e-3)" "unprognostic (2.47e-1)" "unprognostic (1.13e-1)" "unprognostic (5.64e-3)" "unprognostic (6.42e-2)" 13.7 9.5 6.2 19.9 8.8 16.8 13.9 9.8 6.3 13.2 7.7 13.1 10.6 12.7 11.1 10.6 10.9 12.7 10.5 5.1 7.8 11.9 16.7 15.4 27.4 8.7 7.0 13.0 9.2 18.3 6.0 14.3 9.6 13.0 12.8 13.2 9.0 12.7 12.9 12.3 13.2 12.8 8.0 27.6 12.9 31.9 7.7 25.4 33.0 12.8 26.3 15.7 8.5 13.2 15.1 19.9 22.5 24.4 28.3 34.1 13.5 19.6 21.9 15.6 14.6 21.1 16.8 25.6 9.4 36.9 38.3 30.2 22.8 17.0 17.0 24.6 9.9 26.9 22.7 18.4 26.5 41.8 31.2 24.0 26.2 26.6 23.6 19.1 25.4 17.8 31.7 20.0 18.3 21.8 25.9 15.8 24.2 25.4 15.4 24.2 32.6 17.2 17.1 19.5 14.0 21.4 32.4 14.2 18.2 29.7 19.7 21.2 29.3 32.5 14.0 22.1 19.0 12.2 22.0 38.6 14.9 16.3 17.8 10.5 4.4 4.7 5.3 4.1 5.6 5.5 3.9 4.1 3.3 6.9 4.2 3.7 15.1 5.2 4.9 5.0 3.2 2.3 6.2 8.8 9.8 6.3 5.1 7.8 8.7 7.0 9.6 8.0 7.7 13.2 76.2 60.9 45.7 75.1 85.6 30.2 34.6 26.6 38.7 31.2 24.1 22.7 61.3 17.2 43.9 20.2 29.2 13.7 96.8 37.6 3.9 20.0 7.6 62.7 68.0 58.7 14.5 25.5 73.7 14.7 10.6 52.9 44.4 89.7 58.2 38.3 51.4 33.0 28.8 67.3 64.8 30.6 16.2 73.1 37.6 13.8 30.7 75.5 12.4 131.2 75.8 20.7 87.6 65.9 113.0 23.2 31.9 36.1 61.8 49.3 25.6 18.5 54.4 28.7 13.1 44.9 42.5 145.2 38.5 35.1 33.5 9.4 65.9 53.7 26.9 46.4 SFR1 "bA373N18.1, C10orf78, FLJ41960, MEI5, MEIR5" ENSG00000156384 "SWI5 dependent homologous recombination repair protein 1" Q86XK3 10 104122058-104126385 "Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 7 "Spermatocytes: 233.6;Spermatogonia: 76.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA039617 Uncertain NA NA "Cluster 44: Non-specific - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA039617: AB_10805482" "unprognostic (2.79e-2)" "unprognostic (2.58e-3)" "unprognostic (1.94e-2)" "unprognostic (3.78e-1)" "unprognostic (8.54e-2)" "unprognostic (4.42e-3)" "prognostic unfavorable (2.59e-5)" "unprognostic (6.20e-2)" "unprognostic (9.39e-2)" "unprognostic (5.19e-2)" "unprognostic (8.88e-3)" "unprognostic (2.21e-2)" "prognostic unfavorable (2.23e-4)" "unprognostic (2.86e-2)" "unprognostic (4.66e-2)" "unprognostic (8.44e-2)" "unprognostic (2.24e-2)" 4.8 4.4 5.6 7.2 8.2 10.0 6.6 7.1 7.9 3.8 6.1 5.2 4.7 5.4 7.3 4.9 5.4 4.9 7.6 5.5 5.9 4.9 3.1 6.3 9.0 7.9 7.0 8.9 5.9 3.5 2.9 3.9 7.6 3.9 6.4 4.2 4.0 3.4 4.1 4.4 6.1 5.6 6.5 6.3 5.5 18.3 7.0 11.7 7.3 5.3 7.6 5.4 3.2 11.2 22.2 12.4 13.1 5.5 5.0 8.9 7.7 11.6 14.0 7.4 9.7 5.5 45.7 17.7 10.9 3.1 15.5 18.4 6.6 15.8 11.8 15.6 7.5 13.3 5.4 7.0 9.3 15.7 8.5 4.9 5.8 14.8 20.3 9.9 15.3 18.2 8.6 12.5 9.3 6.8 16.0 28.3 6.2 13.0 9.0 19.8 19.1 9.4 16.0 5.9 7.2 7.4 7.4 4.0 9.9 10.9 10.1 6.9 7.1 4.2 15.2 12.9 18.8 14.9 19.2 18.0 12.2 16.6 5.7 23.6 16.8 10.4 14.3 16.5 14.6 16.6 14.9 15.2 11.9 19.2 21.7 18.3 5.4 12.8 12.1 10.3 13.5 14.9 5.6 8.2 7.1 7.9 5.5 5.9 7.9 7.0 7.6 6.5 7.0 11.2 12.1 3.2 11.8 1.3 9.9 21.5 14.6 10.4 2.8 3.5 6.8 7.0 8.5 8.6 13.8 1.8 0.0 9.7 9.8 4.7 17.6 12.1 20.0 8.0 6.3 13.7 3.0 21.8 1.3 12.3 13.7 10.2 2.6 7.8 12.0 8.1 18.2 1.9 17.6 5.0 2.6 6.3 18.3 16.3 12.4 11.3 9.6 12.5 3.6 4.7 17.8 9.6 15.5 1.0 14.0 19.1 5.1 6.0 4.5 5.1 5.7 10.1 5.3 4.9 0.0 13.0 9.0 233.6 76.7 5.5 7.4 3.8 10.4 5.6 7.2 8.7 SHCBP1 "FLJ22009, PAL" ENSG00000171241 "SHC binding and spindle associated 1" Q8NEM2 16 46578591-46621379 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 17.4;lymphoid tissue: 10.6" "Cell type enhanced" "Detected in many" "Erythroid cells: 36.2;Extravillous trophoblasts: 28.7;Plasma cells: 38.3;Spermatocytes: 33.7;Spermatogonia: 23.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA048876 Uncertain Approved "Nuclear bodies,Microtubules,Midbody,Mitotic spindle" Yes Yes "Cluster 19: B-cells - Humoral immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear bodies" "Microtubules, Midbody, Mitotic spindle" "HPA048876: AB_2680542" "unprognostic (2.44e-3)" "unprognostic (1.13e-1)" "unprognostic (2.98e-2)" "unprognostic (2.74e-1)" "unprognostic (2.54e-2)" "unprognostic (2.35e-2)" "unprognostic (2.96e-4)" "unprognostic (2.26e-3)" "unprognostic (5.35e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (4.47e-5)" "unprognostic (4.81e-2)" "unprognostic (2.22e-16)" "unprognostic (3.59e-2)" "unprognostic (3.86e-2)" "unprognostic (2.66e-1)" "unprognostic (2.66e-1)" 0.7 0.5 0.5 5.1 0.5 17.4 0.9 1.2 0.6 0.6 0.4 1.9 1.2 0.6 0.6 3.5 0.2 0.6 1.0 0.4 0.2 5.4 0.2 1.0 9.8 0.4 0.3 0.3 0.2 0.2 0.2 2.4 0.4 0.3 2.2 0.2 0.8 0.2 1.5 3.3 1.5 1.7 0.1 4.4 0.9 5.2 0.5 8.8 0.3 0.2 10.6 1.2 1.2 0.7 33.8 30.8 11.9 15.3 3.1 6.2 16.2 60.7 24.6 59.2 26.8 14.6 20.8 28.0 30.2 28.8 26.8 21.0 29.3 21.7 73.8 17.7 17.2 28.2 25.8 30.3 0.1 28.5 35.4 1.2 1.6 45.9 18.1 5.9 33.0 14.9 12.7 28.3 69.7 21.5 24.0 23.7 10.0 17.2 31.6 45.4 89.9 44.8 13.7 9.4 5.0 7.2 46.0 23.7 11.1 11.4 13.0 23.4 16.1 43.9 28.7 43.5 54.0 24.9 36.7 46.7 21.4 31.3 45.8 0.2 0.3 0.6 0.2 0.5 0.0 1.7 0.3 0.1 0.3 1.2 0.0 0.1 0.4 0.1 2.4 0.7 1.2 1.1 0.5 0.5 1.2 0.6 0.4 0.2 0.4 0.3 0.4 0.1 0.5 0.7 0.2 0.0 1.1 1.3 7.1 1.7 0.7 1.2 0.0 0.3 0.6 1.1 1.9 1.5 1.4 0.0 0.0 11.3 0.8 1.9 0.0 0.2 8.4 0.7 1.7 1.7 0.0 36.2 2.1 0.0 28.7 3.7 4.1 1.5 0.0 7.6 1.8 0.3 12.6 0.0 0.7 2.2 2.0 4.5 3.3 2.3 0.6 4.0 1.8 2.8 2.8 0.8 0.0 1.0 0.5 0.1 0.1 0.4 38.3 0.5 0.4 0.1 0.1 0.3 0.0 0.5 6.3 33.7 23.7 3.6 0.6 3.7 2.2 0.8 3.4 1.1 SLC16A10 "MCT10, TAT1" ENSG00000112394 "Solute carrier family 16 member 10" Q8TF71 6 111087503-111231194 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 53.7;skeletal muscle: 41.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 32.8;Excitatory neurons: 33.9;Inhibitory neurons: 47.8;Macrophages: 33.8;Melanocytes: 44.4" "Cancer enriched" "Detected in many" 6 "testis cancer: 4.5" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 1.7;T-reg: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HAP1: 49.4;HEK 293: 20.2;RPMI-8226: 37.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA016860 Approved Supported "Vesicles,Cell Junctions" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 25: RPMI-8226 - Immune response" "Cluster 41: Macrophages - Immune response" "Vesicles, Cell Junctions" "HPA016860: AB_2189211" "unprognostic (2.03e-1)" "unprognostic (2.08e-1)" "unprognostic (6.11e-2)" "unprognostic (3.56e-4)" "unprognostic (2.24e-1)" "unprognostic (2.15e-1)" "unprognostic (1.64e-1)" "unprognostic (1.89e-1)" "unprognostic (1.86e-3)" "unprognostic (5.22e-1)" "unprognostic (1.74e-2)" "unprognostic (1.06e-1)" "unprognostic (1.10e-3)" "unprognostic (2.73e-1)" "unprognostic (1.60e-1)" "unprognostic (1.33e-1)" "unprognostic (1.91e-1)" 2.9 5.5 1.4 3.0 8.6 0.8 0.8 4.2 3.4 0.6 53.7 1.2 8.5 0.5 1.4 0.8 0.8 1.5 2.3 2.0 1.2 10.0 13.5 4.6 0.9 1.1 5.0 0.9 29.7 7.9 1.0 23.7 2.8 1.3 1.8 0.7 3.1 0.2 41.2 15.3 5.0 0.3 0.2 1.8 5.3 4.2 9.6 10.9 2.7 6.0 1.3 1.9 1.2 1.1 0.9 1.0 0.4 2.2 0.1 0.1 3.1 0.0 0.2 0.8 1.2 9.0 0.4 5.2 1.4 0.3 2.5 0.1 49.4 0.1 1.0 0.1 20.2 8.2 0.7 7.4 0.1 7.6 7.4 0.0 0.0 0.1 0.0 0.2 0.0 10.9 1.4 0.2 0.1 3.6 9.8 0.8 14.6 0.2 3.2 5.4 6.8 37.2 0.0 0.5 10.7 3.3 0.2 0.7 1.8 3.6 1.8 0.9 0.1 0.1 1.8 0.5 2.5 2.6 0.1 1.5 0.3 5.8 0.8 0.4 0.0 0.0 0.1 0.0 0.1 0.1 0.4 0.1 0.0 0.2 1.7 1.5 0.3 0.1 0.0 0.1 1.6 0.1 1.4 8.6 4.2 3.4 2.0 1.2 1.1 5.0 2.8 0.2 9.6 1.1 0.4 9.6 32.8 2.0 1.5 9.7 10.7 0.0 4.6 6.9 2.0 1.3 9.1 0.0 3.1 5.5 2.1 1.9 0.7 2.1 1.9 0.2 9.0 0.4 0.8 1.4 6.6 1.7 33.9 12.5 1.8 8.9 3.6 1.3 1.3 2.5 4.2 25.4 21.4 1.7 47.8 4.8 0.0 12.4 12.4 8.2 0.0 33.8 44.4 0.0 0.7 1.6 0.0 16.6 0.3 2.0 0.9 0.0 4.8 3.9 10.9 17.7 0.7 0.7 0.0 18.5 1.0 11.6 11.2 1.2 14.8 1.2 5.8 9.2 8.5 1.2 SMC1B "bK268H5, SMC1L2" ENSG00000077935 "Structural maintenance of chromosomes 1B" Q8NDV3 22 45344063-45413619 "Predicted intracellular proteins" "Cell cycle, Meiosis" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 98 "testis: 31.1" "Group enriched" "Detected in some" 6 "Spermatocytes: 897.6;Spermatogonia: 448.5" "Cancer enriched" "Detected in many" 6 "cervical cancer: 4.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 8.9;EFO-21: 4.0;SiHa: 18.0;U-266/70: 3.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA001500 Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 20: HeLa - Mitochondria" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA001500: AB_1080030" "unprognostic (1.18e-2)" "unprognostic (6.16e-3)" "unprognostic (2.22e-1)" "unprognostic (3.38e-3)" "unprognostic (1.77e-1)" "unprognostic (3.21e-2)" "unprognostic (6.18e-2)" "unprognostic (1.87e-3)" "unprognostic (3.41e-2)" "unprognostic (3.65e-1)" "unprognostic (4.49e-2)" "unprognostic (3.79e-1)" "unprognostic (3.83e-9)" "unprognostic (2.10e-1)" "unprognostic (1.11e-2)" "unprognostic (1.78e-1)" "unprognostic (1.98e-3)" 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 31.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 8.9 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.7 0.1 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.1 0.0 0.2 0.2 0.2 0.1 0.0 0.1 0.1 0.0 0.0 0.4 0.2 0.1 0.0 18.0 0.0 0.0 0.0 0.1 1.5 0.1 0.0 0.0 0.4 0.0 3.9 0.0 0.0 0.0 0.3 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.1 0.0 0.2 0.1 0.0 0.0 0.3 0.6 0.8 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.1 75.6 0.5 0.2 0.8 0.0 0.0 1.4 0.0 0.9 0.3 0.0 0.2 0.0 0.7 0.4 0.1 0.1 0.0 1.1 0.0 0.0 0.3 0.0 36.9 5.6 0.5 0.0 1.0 0.0 0.3 0.0 1.0 1.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.2 1.0 98.6 0.4 0.2 897.6 448.5 0.0 0.0 0.8 0.1 0.0 0.0 0.2 SMC4 "CAP-C, hCAP-C, SMC4L1" ENSG00000113810 "Structural maintenance of chromosomes 4" Q9NTJ3 3 160399274-160434954 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA condensation, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 60.6" "Cell type enhanced" "Detected in many" "Erythroid cells: 305.8;Spermatocytes: 339.8;Spermatogonia: 239.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "basophil: 74.4" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029449, CAB055509" Approved Supported "Nuclear speckles,Cytosol" NA Yes 25000 "Cluster 18: Basophils - Vesicular transport" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear speckles, Cytosol" "CAB055509: , HPA029449: AB_10603891" "unprognostic (2.63e-1)" "unprognostic (1.01e-1)" "unprognostic (2.45e-2)" "prognostic unfavorable (7.63e-4)" "unprognostic (2.22e-1)" "unprognostic (1.28e-2)" "prognostic unfavorable (2.94e-4)" "unprognostic (9.54e-2)" "unprognostic (2.18e-2)" "unprognostic (5.47e-2)" "prognostic unfavorable (4.20e-5)" "prognostic unfavorable (9.00e-4)" "prognostic unfavorable (8.05e-7)" "unprognostic (3.03e-2)" "unprognostic (4.46e-1)" "unprognostic (1.06e-1)" "unprognostic (4.98e-2)" 6.8 6.5 1.0 21.2 2.0 36.3 6.8 1.2 1.7 6.3 1.5 13.2 14.0 7.4 2.3 23.5 4.5 7.6 7.3 0.9 1.9 5.9 7.8 11.8 37.1 1.7 1.4 5.9 7.8 3.8 2.0 16.2 1.6 5.8 14.9 7.7 4.6 5.0 3.6 11.0 15.4 10.1 1.3 14.7 11.8 32.5 1.9 60.6 9.0 6.8 31.6 9.6 4.3 3.2 386.3 72.8 155.0 73.0 31.5 30.9 72.1 181.2 88.8 206.0 176.8 94.4 209.7 236.6 101.9 81.1 140.0 212.5 183.0 95.0 332.4 297.9 113.8 234.7 123.3 33.6 17.3 158.3 182.6 14.6 13.3 114.4 96.5 78.5 94.8 103.2 130.3 272.2 133.9 78.3 183.2 44.4 91.8 106.7 149.3 180.1 238.8 177.3 43.4 54.8 93.7 94.0 141.4 135.1 65.5 76.6 156.9 128.6 84.8 132.2 105.2 119.9 349.8 181.1 192.2 412.0 96.7 166.9 151.9 74.4 6.0 23.6 11.5 8.9 11.4 17.2 18.2 14.3 6.6 15.0 11.4 10.2 10.8 15.3 15.9 11.7 30.3 9.5 1.0 2.0 1.2 1.7 0.9 1.9 1.7 1.4 1.6 1.3 1.9 3.2 24.6 105.8 174.0 3.9 43.7 40.8 18.2 33.1 30.7 14.9 21.5 21.0 41.3 25.8 35.0 35.0 8.4 74.6 54.4 41.4 3.9 20.9 48.6 35.2 27.0 44.8 30.1 305.8 3.5 14.7 138.1 50.7 32.6 36.1 79.1 77.3 38.2 20.4 61.3 0.0 2.9 44.5 24.4 29.7 43.5 28.3 25.1 36.4 17.8 17.8 39.3 9.3 46.4 3.5 30.1 13.5 26.5 48.2 95.9 14.1 25.9 8.6 25.4 25.8 131.5 21.7 73.2 339.8 239.4 58.1 35.7 34.1 58.4 34.6 69.7 19.1 SMCHD1 "FSHD2, KIAA0650" ENSG00000101596 "Structural maintenance of chromosomes flexible hinge domain containing 1" A6NHR9 18 2655726-2805017 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "Chromatin regulator, DNA-binding, Hydrolase" "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome, Microphthalmia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "B-cells: 363.7;Plasma cells: 391.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 8 "neutrophil: 58.7" "Lineage enriched" "Detected in all" 8 "granulocytes: 58.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039441 Approved Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 2: Immune cells - Immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "Nuclear bodies" "HPA039441: AB_10671042" "unprognostic (2.99e-2)" "unprognostic (5.14e-2)" "unprognostic (1.33e-2)" "unprognostic (9.03e-2)" "unprognostic (8.66e-2)" "unprognostic (1.36e-2)" "prognostic unfavorable (5.39e-4)" "unprognostic (1.32e-1)" "unprognostic (4.14e-2)" "unprognostic (3.11e-3)" "unprognostic (3.32e-2)" "unprognostic (2.70e-2)" "prognostic unfavorable (1.40e-4)" "unprognostic (1.35e-1)" "unprognostic (1.00e-1)" "unprognostic (8.92e-2)" "unprognostic (2.63e-2)" 13.6 6.9 5.4 24.6 6.6 41.1 12.4 11.4 8.3 16.5 6.8 14.4 13.7 14.9 9.2 8.7 14.1 12.4 10.1 5.0 6.6 6.5 8.4 19.0 33.9 7.2 6.1 15.4 16.3 11.9 7.9 16.3 7.4 13.4 14.7 16.3 10.1 11.2 11.0 9.1 20.3 12.8 6.4 28.6 12.4 14.1 6.3 25.6 9.6 11.5 22.4 15.0 14.2 8.7 24.1 10.7 35.8 22.6 15.0 21.8 25.7 23.7 16.8 22.0 27.7 20.3 7.7 51.6 10.2 21.2 24.7 13.0 29.1 13.6 34.4 10.7 15.1 32.3 21.7 19.5 16.8 93.9 24.3 14.4 12.2 27.9 22.8 16.8 18.3 25.5 38.3 31.1 21.3 8.6 39.4 23.9 14.4 13.0 12.4 31.7 29.1 22.9 13.6 36.5 29.2 18.4 32.0 10.6 18.8 19.8 7.9 39.3 17.5 27.1 37.4 37.1 44.0 18.8 30.4 46.5 17.4 17.1 24.0 5.1 2.5 6.6 3.6 1.7 2.6 5.8 4.8 4.3 0.9 7.5 5.9 3.8 58.7 2.3 2.3 2.6 5.4 1.3 5.4 6.6 11.4 8.3 5.0 6.6 7.2 6.1 7.4 6.4 6.3 8.7 96.5 44.8 44.7 71.5 363.7 27.1 35.3 14.5 48.9 112.1 33.3 32.8 53.0 15.7 27.7 18.4 100.1 36.5 232.7 102.7 5.9 23.4 117.2 43.6 83.3 53.0 22.7 69.0 98.4 19.4 22.3 52.8 68.3 75.9 40.4 54.2 30.7 16.4 19.4 99.3 127.2 35.5 10.2 65.4 69.7 38.6 42.0 116.3 30.2 121.8 142.5 32.3 120.5 111.1 130.4 23.6 60.1 38.0 391.1 52.0 46.5 6.1 22.5 88.5 39.5 59.7 69.8 166.7 115.3 41.3 24.9 46.9 257.9 45.9 30.4 57.8 SNAPC1 "PTFgamma, SNAP43" ENSG00000023608 "Small nuclear RNA activating complex polypeptide 1" Q16533 14 61762420-61796428 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 171.9;Spermatocytes: 215.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "GAMG: 153.7;hTERT-HME1: 153.7;U-2 OS: 207.6;U-251 MG: 146.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA067076, HPA072276" Enhanced Nucleoplasm,Nucleoli NA NA "Cluster 17: Basophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 9: U-2 OS - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoli Nucleoplasm "HPA067076: AB_2732757, HPA072276: AB_2732199" "unprognostic (7.40e-2)" "unprognostic (5.04e-2)" "unprognostic (3.09e-2)" "unprognostic (1.11e-1)" "unprognostic (2.94e-1)" "unprognostic (8.55e-2)" "unprognostic (1.68e-3)" "unprognostic (1.88e-1)" "unprognostic (4.01e-2)" "unprognostic (5.18e-2)" "unprognostic (1.58e-1)" "unprognostic (1.99e-1)" "unprognostic (2.47e-3)" "unprognostic (1.58e-1)" "unprognostic (1.07e-1)" "unprognostic (3.10e-1)" "unprognostic (2.26e-1)" 6.2 9.0 2.7 6.4 3.6 6.0 5.9 4.9 3.4 10.1 4.1 3.5 3.6 7.0 4.9 6.0 6.4 7.7 8.3 2.7 2.9 7.0 5.2 4.8 8.1 4.3 5.7 6.1 3.6 7.9 5.8 8.7 4.5 6.8 3.0 6.6 5.2 6.9 4.4 5.2 3.2 4.8 3.0 6.8 3.2 20.0 3.0 7.1 7.2 4.7 6.9 10.0 5.2 4.6 57.6 11.0 10.7 22.8 11.7 13.6 12.7 47.4 31.4 53.3 31.4 3.9 11.5 11.9 61.5 20.3 153.7 17.7 10.6 14.3 87.3 13.0 7.6 7.1 5.7 8.1 30.8 7.5 15.2 13.1 9.5 45.0 153.7 20.7 20.7 16.2 8.0 10.6 51.4 7.4 18.3 12.0 10.3 6.4 35.9 13.9 28.3 4.4 43.9 8.8 7.6 18.3 31.3 5.5 39.0 13.2 11.0 11.7 31.8 58.4 207.6 38.2 146.6 7.0 7.8 10.5 39.7 9.5 35.3 7.7 5.0 4.5 4.4 4.3 5.7 8.4 5.4 3.8 5.2 8.8 8.8 5.7 4.9 7.0 3.8 6.9 6.5 3.6 2.7 3.6 4.9 3.4 2.7 2.9 4.3 5.7 4.5 3.0 3.0 4.6 22.6 35.3 18.3 10.1 28.0 95.3 56.2 171.9 43.3 10.2 11.5 18.0 24.6 11.5 53.6 29.5 2.1 16.8 31.2 3.4 7.9 28.6 70.7 70.1 28.7 29.3 4.2 10.7 12.8 15.9 31.5 31.1 4.1 47.6 41.8 20.2 26.7 6.9 17.3 8.4 13.3 4.0 42.7 11.7 32.6 17.1 22.1 31.6 17.8 10.3 12.4 40.4 4.1 10.6 14.6 20.3 1.9 20.3 7.9 28.8 5.6 13.3 83.9 12.6 19.7 38.3 34.7 215.0 67.7 23.5 64.5 5.6 29.0 20.6 6.8 20.8 SOS2 ENSG00000100485 "SOS Ras/Rho guanine nucleotide exchange factor 2" Q07890 14 50117130-50231578 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 8.0" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004577, HPA047368, HPA052689" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 8: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 44: Endometrium - Transcription" Nucleoplasm Vesicles "CAB004577: AB_628270, HPA047368: AB_2680014, HPA052689: AB_2681917" "unprognostic (7.99e-2)" "unprognostic (6.17e-2)" "unprognostic (7.80e-2)" "unprognostic (4.93e-2)" "unprognostic (2.81e-2)" "unprognostic (7.64e-2)" "unprognostic (1.56e-1)" "unprognostic (3.08e-1)" "unprognostic (2.01e-1)" "unprognostic (3.88e-1)" "unprognostic (9.99e-2)" "unprognostic (8.21e-2)" "prognostic favorable (8.48e-8)" "unprognostic (2.47e-2)" "unprognostic (1.91e-1)" "unprognostic (1.01e-1)" "unprognostic (6.57e-2)" 23.8 14.9 15.3 15.3 21.4 39.5 17.9 18.2 19.5 14.3 13.5 17.4 21.5 15.2 22.4 16.4 12.7 12.9 21.5 14.0 16.8 24.5 13.2 15.8 14.4 19.7 18.6 15.3 15.9 39.3 9.1 17.0 19.1 15.4 17.3 14.0 14.5 18.7 57.6 17.9 24.5 18.0 16.8 17.8 13.7 27.9 19.6 16.5 25.1 63.8 13.5 14.8 10.5 23.9 15.3 11.1 22.1 14.9 16.6 18.0 10.4 13.5 14.8 10.0 12.5 4.9 19.8 16.0 11.9 17.3 17.3 13.8 12.1 10.2 17.7 26.9 4.4 16.1 8.5 8.5 18.3 19.1 16.6 18.8 24.6 9.3 21.6 25.2 21.8 13.1 12.5 39.0 24.2 12.7 15.9 15.1 6.9 11.4 9.6 17.0 30.8 12.1 16.1 14.4 16.0 18.7 15.0 17.5 17.8 15.9 19.4 23.0 24.1 27.3 17.8 12.5 8.9 27.3 31.7 19.6 7.1 10.5 16.4 8.0 1.1 2.8 1.1 0.9 0.9 0.6 0.7 0.8 0.8 0.7 0.8 0.7 4.6 1.7 2.0 1.4 0.0 0.4 15.3 21.4 18.2 19.5 14.0 16.8 19.7 18.6 19.1 16.8 19.6 23.9 34.1 9.6 26.3 59.4 18.4 35.7 20.9 10.5 10.2 17.2 23.8 15.6 43.7 17.2 18.2 18.4 16.7 8.2 46.3 36.0 7.9 11.3 17.0 18.7 30.4 23.5 20.4 6.3 71.5 10.7 8.0 22.2 12.8 29.8 20.3 37.4 22.9 13.8 8.8 25.2 89.6 18.5 12.2 33.3 17.5 8.6 12.5 29.0 17.8 80.6 29.0 17.6 21.6 100.5 104.8 14.5 24.6 13.5 28.6 27.3 28.6 15.8 14.3 22.5 19.7 43.4 30.8 54.3 12.3 17.7 39.6 13.0 24.2 17.4 14.9 30.6 SPG11 "ALS5, FLJ21439, KIAA1840" ENSG00000104133 "SPG11 vesicle trafficking associated, spatacsin" Q96JI7 15 44562696-44663678 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Amyotrophic lateral sclerosis, Charcot-Marie-Tooth disease, Hereditary spastic paraplegia, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 121.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040412, HPA040947" Approved Supported "Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 52: Non-specific - Transcription" "Plasma membrane, Cytosol" Nucleoli "HPA040412: AB_10795418, HPA040947: AB_10796232" "unprognostic (1.10e-1)" "unprognostic (1.74e-1)" "unprognostic (2.39e-1)" "unprognostic (1.98e-3)" "unprognostic (1.99e-1)" "unprognostic (9.31e-2)" "unprognostic (2.91e-1)" "unprognostic (2.32e-1)" "unprognostic (6.71e-2)" "unprognostic (2.26e-3)" "unprognostic (2.58e-2)" "unprognostic (9.19e-2)" "prognostic favorable (6.28e-5)" "unprognostic (8.73e-2)" "unprognostic (2.48e-1)" "unprognostic (3.72e-1)" "unprognostic (6.06e-2)" 21.1 27.1 18.4 18.2 25.7 27.4 21.6 24.4 21.3 21.5 23.9 25.6 17.1 17.9 25.3 25.6 20.2 16.1 25.5 17.5 22.2 25.0 29.8 24.8 28.4 23.8 22.1 21.4 28.6 26.7 21.3 14.9 23.9 25.3 19.9 30.5 24.7 15.0 22.9 30.4 30.1 12.7 19.1 43.0 26.0 25.5 24.6 23.7 30.9 14.3 18.6 23.8 22.6 33.4 13.2 8.8 21.9 21.6 33.7 33.0 15.8 13.4 17.4 13.0 16.6 10.8 12.5 9.7 16.5 18.2 22.5 29.0 15.1 20.8 12.5 29.3 9.0 22.1 21.1 16.4 23.7 22.2 19.2 25.3 23.3 10.7 30.5 20.4 18.6 16.6 28.8 24.2 18.6 11.5 10.1 19.7 11.5 40.3 11.6 12.9 18.5 10.6 28.0 33.6 14.2 16.8 14.6 23.3 13.1 18.0 22.0 30.2 19.9 17.1 8.5 21.4 16.5 23.8 22.6 19.2 17.6 28.8 17.9 5.7 7.7 11.8 6.5 9.2 6.9 10.0 5.4 4.9 6.2 11.3 4.3 5.3 11.6 6.2 12.4 6.3 6.1 3.7 18.4 25.7 24.4 21.3 17.5 22.2 23.8 22.1 23.9 19.1 24.6 33.4 21.0 44.8 22.2 56.2 40.4 9.3 15.6 18.8 14.2 25.1 19.0 12.6 20.1 18.6 31.3 27.6 47.9 16.5 30.1 29.3 5.9 21.3 28.2 31.7 23.2 17.6 20.0 22.3 62.9 16.9 10.1 19.3 37.2 33.6 27.3 31.9 21.8 23.5 20.1 16.8 68.1 31.2 26.4 43.3 23.5 33.2 17.7 40.4 14.2 74.9 88.1 14.0 50.4 68.3 121.4 17.7 24.0 13.9 21.4 19.3 30.8 14.9 53.6 21.7 6.6 24.8 16.3 51.7 31.6 20.1 11.1 9.3 29.5 24.4 27.3 22.2 SPO11 "CT35, SPATA43, TOPVIA" ENSG00000054796 "SPO11 initiator of meiotic double stranded breaks" Q9Y5K1 20 57329803-57343994 "Enzymes, Plasma proteins, Predicted intracellular proteins" Meiosis "DNA-binding, Hydrolase, Isomerase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 85 "testis: 8.5" "Cell type enriched" "Detected in some" 9 "Spermatocytes: 98.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 98.2 10.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SQLE ENSG00000104549 "Squalene epoxidase" Q14534 8 124998497-125022283 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018038, HPA020762" Enhanced Uncertain Vesicles,Cytosol NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 37: Intestine - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Vesicles, Cytosol" "HPA018038: AB_2669753, HPA020762: AB_2670512" "unprognostic (1.37e-2)" "unprognostic (6.26e-3)" "unprognostic (5.12e-2)" "unprognostic (9.51e-3)" "unprognostic (4.63e-1)" "prognostic unfavorable (7.42e-4)" "unprognostic (4.76e-3)" "prognostic unfavorable (4.67e-4)" "unprognostic (3.45e-2)" "unprognostic (7.21e-2)" "prognostic unfavorable (2.73e-4)" "unprognostic (7.51e-2)" "prognostic unfavorable (5.70e-4)" "unprognostic (9.71e-2)" "unprognostic (4.62e-2)" "unprognostic (1.19e-3)" "unprognostic (7.74e-3)" 8.6 31.1 17.5 19.6 27.0 23.0 22.1 26.8 24.0 30.7 25.4 21.6 31.0 16.4 9.1 78.7 18.6 10.7 7.2 18.6 24.4 17.1 72.3 30.9 17.7 47.3 27.7 14.3 10.7 22.7 16.5 47.5 35.1 25.0 18.6 17.8 19.1 7.6 1.4 49.4 14.0 12.3 27.6 9.7 21.8 59.4 21.8 14.2 10.5 1.6 29.4 14.7 46.2 34.6 135.5 51.5 301.6 87.2 91.7 154.1 30.5 34.9 106.3 46.5 84.7 70.6 192.3 92.7 49.2 43.2 186.0 101.0 127.3 192.4 53.6 77.1 268.3 265.2 32.6 181.1 134.6 31.5 74.6 106.1 201.4 138.8 113.3 29.8 51.5 64.2 153.8 174.8 38.1 223.7 109.6 39.3 125.2 92.6 35.2 47.5 55.4 126.6 329.3 153.3 93.9 47.6 71.6 226.3 74.1 96.5 60.7 81.3 50.8 19.2 66.0 22.9 31.6 31.6 69.6 126.6 32.0 93.7 33.8 1.5 6.3 0.7 10.6 10.8 5.0 16.6 6.0 9.5 15.2 17.1 8.2 8.6 0.2 12.6 12.7 10.8 7.1 7.7 17.5 27.0 26.8 24.0 18.6 24.4 47.3 27.7 35.1 27.6 21.8 34.6 13.2 60.9 97.9 21.5 34.7 22.9 64.0 199.9 16.5 41.8 35.6 27.3 6.1 31.5 129.6 53.3 50.1 99.7 20.6 81.6 7.9 60.3 21.0 95.9 23.3 39.7 31.7 22.3 14.3 83.6 133.7 35.3 51.0 80.5 41.3 77.1 9.7 127.9 61.1 148.0 18.8 58.0 126.1 10.9 30.1 13.2 23.9 22.2 21.4 13.1 91.0 24.3 8.2 20.1 77.9 98.6 38.4 10.9 30.6 118.0 17.3 3.7 123.0 61.1 26.3 12.5 42.0 179.5 128.6 69.5 89.1 217.1 21.1 171.8 35.0 114.8 SRR "ILV1, ISO1" ENSG00000167720 "Serine racemase" Q9GZT4 17 2303383-2325260 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Allosteric enzyme, Isomerase, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 23.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007529, CAB015343" Approved Approved Vesicles NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Vesicles "CAB015343: AB_2195009, HPA007529: AB_2667853" "unprognostic (2.96e-1)" "unprognostic (7.86e-2)" "unprognostic (6.01e-2)" "prognostic favorable (6.20e-5)" "unprognostic (3.05e-1)" "unprognostic (1.57e-2)" "unprognostic (4.32e-2)" "unprognostic (9.97e-2)" "unprognostic (9.09e-2)" "unprognostic (4.85e-2)" "prognostic favorable (8.16e-4)" "unprognostic (5.17e-2)" "prognostic favorable (2.45e-6)" "unprognostic (6.14e-2)" "unprognostic (1.99e-1)" "unprognostic (1.89e-1)" "unprognostic (5.84e-2)" 10.5 7.8 11.0 6.6 11.5 13.9 8.9 12.5 13.1 6.8 13.0 9.4 6.9 7.5 10.3 10.9 8.7 8.3 10.9 9.4 13.4 9.0 8.2 6.1 6.6 11.2 12.4 8.4 11.9 12.3 4.9 5.4 12.7 8.4 7.5 16.6 10.7 7.7 15.6 11.8 5.9 7.0 11.1 6.9 8.0 7.1 12.5 9.0 11.8 6.7 5.4 8.4 5.3 11.8 14.8 27.0 42.7 17.9 24.9 24.4 22.8 29.8 20.2 19.4 20.5 25.3 18.1 27.5 4.1 29.1 14.3 30.2 12.2 11.4 24.6 32.6 26.0 14.6 20.3 9.6 22.5 4.3 8.0 22.9 11.5 41.4 21.0 21.2 28.6 28.2 15.2 19.8 43.9 8.4 28.7 5.8 10.0 13.8 19.9 45.5 48.8 13.3 22.9 6.9 9.2 23.4 26.8 3.3 14.3 14.6 20.7 10.3 21.3 21.4 14.7 24.7 19.0 16.7 26.0 5.1 36.9 13.7 29.8 4.3 8.1 5.6 8.8 8.4 9.1 10.1 11.2 9.1 15.6 10.2 9.2 12.1 1.0 15.7 14.0 11.0 8.8 8.5 11.0 11.5 12.5 13.1 9.4 13.4 11.2 12.4 12.7 11.1 12.5 11.8 5.0 3.2 3.7 3.6 2.1 2.9 3.5 17.4 1.8 8.5 5.5 4.6 4.2 1.5 8.4 1.8 0.0 5.9 3.4 3.0 13.7 9.6 1.9 6.6 5.5 5.4 1.8 5.2 3.5 6.6 3.2 5.7 3.6 4.6 0.0 13.2 8.2 3.2 9.3 16.8 4.9 2.5 12.2 4.6 4.9 1.5 4.1 3.7 5.4 4.7 9.3 11.0 5.2 5.0 7.8 6.7 0.8 5.3 6.1 2.9 2.9 6.3 10.2 5.6 0.0 4.6 6.5 23.3 13.1 4.7 2.4 3.4 2.3 9.7 3.5 4.0 STAG3 ENSG00000066923 "Stromal antigen 3" Q9UJ98 7 100177563-100221488 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Chromosome partition, Meiosis" "Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 66 "testis: 54.7" "Cell type enhanced" "Detected in many" "B-cells: 56.5;Spermatocytes: 152.6;Spermatogonia: 60.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 41.7;HMC-1: 54.4;U-698: 13.1" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA049106, HPA058330" Enhanced Approved Nucleoplasm,Nucleoli NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 3: HMC-1 - Innate immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoli Nucleoplasm "HPA049106: AB_2680634, HPA058330: AB_2683681" "unprognostic (6.56e-4)" "prognostic favorable (8.45e-4)" "unprognostic (1.25e-2)" "unprognostic (7.54e-2)" "unprognostic (1.73e-1)" "unprognostic (1.86e-3)" "unprognostic (3.59e-2)" "unprognostic (4.62e-2)" "unprognostic (1.12e-1)" "unprognostic (3.46e-1)" "unprognostic (3.31e-4)" "unprognostic (4.26e-4)" "unprognostic (7.48e-2)" "unprognostic (6.80e-2)" "unprognostic (2.72e-1)" "unprognostic (3.13e-2)" "unprognostic (5.07e-4)" 0.2 0.2 0.1 0.1 0.1 0.8 0.3 0.2 0.2 0.2 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.3 0.2 0.0 0.3 0.1 0.3 0.1 0.2 0.1 0.1 0.0 0.3 0.1 0.0 0.1 0.4 0.1 0.0 0.1 0.2 0.1 54.7 0.3 0.6 0.1 0.0 0.2 0.1 0.1 0.3 0.1 0.0 0.1 0.0 0.2 0.0 41.7 1.1 0.0 0.1 0.2 0.0 0.0 1.2 0.1 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 54.4 0.0 0.1 0.8 0.2 0.0 0.3 1.4 0.2 0.0 0.0 0.0 0.4 0.0 0.7 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.1 0.0 13.1 0.7 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.2 0.2 0.1 0.1 0.2 0.0 0.1 0.1 0.3 0.3 1.9 0.0 2.7 2.9 56.5 6.8 10.9 1.8 1.2 7.4 1.9 1.8 2.2 10.0 1.7 7.3 2.1 2.0 12.1 1.7 13.7 0.3 29.8 26.1 2.9 4.2 1.2 8.4 6.5 0.2 3.3 4.1 0.5 7.8 1.3 4.9 4.2 29.4 2.2 20.2 6.1 5.7 0.0 2.2 8.6 23.5 4.7 4.6 5.4 5.6 4.2 2.7 13.4 5.0 5.1 0.2 0.5 1.9 2.1 8.2 1.1 6.9 15.1 7.0 0.0 8.0 5.4 152.6 60.0 0.4 8.5 2.9 10.8 2.6 2.0 11.7 STIL "MCPH7, SIL" ENSG00000123473 "STIL centriolar assembly protein" Q15468 1 47250139-47314147 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein" "Cancer-related genes, Disease variant, Mental retardation, Primary microcephaly, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 10.8;lymphoid tissue: 9.9" "Cell type enhanced" "Detected in many" "Erythroid cells: 12.8;Glandular and luminal cells: 12.4;Spermatocytes: 17.8;Spermatogonia: 14.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA046543 Approved "Plasma membrane,Cytosol" NA Yes "Cluster 40: NK-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Cytosol" "HPA046543: AB_2679692" "unprognostic (2.07e-1)" "unprognostic (6.29e-2)" "unprognostic (5.54e-3)" "unprognostic (2.67e-3)" "unprognostic (1.76e-1)" "unprognostic (1.56e-2)" "unprognostic (2.90e-5)" "unprognostic (7.35e-3)" "unprognostic (4.04e-3)" "unprognostic (1.41e-1)" "prognostic unfavorable (1.33e-4)" "unprognostic (5.81e-2)" "unprognostic (3.36e-14)" "unprognostic (5.76e-3)" "unprognostic (2.58e-1)" "unprognostic (1.64e-1)" "unprognostic (2.28e-1)" 1.0 0.5 0.8 3.0 0.8 10.8 2.9 0.7 1.2 1.1 0.2 4.1 2.9 1.4 1.4 2.5 0.9 1.4 0.6 0.8 0.6 0.7 1.0 0.9 4.9 0.7 0.6 0.8 0.7 0.9 0.4 1.9 0.8 1.3 5.6 1.2 1.7 0.5 0.6 3.1 2.7 1.4 0.4 1.4 1.8 6.6 0.8 9.9 0.9 0.7 5.7 1.1 1.0 1.0 33.7 17.4 24.7 22.1 1.8 3.8 15.7 29.3 14.0 32.0 33.2 18.5 16.1 39.4 13.3 14.4 32.7 21.4 29.4 15.3 33.7 29.6 12.9 44.5 20.9 16.6 0.8 35.7 21.5 1.6 2.1 27.2 17.5 3.8 21.5 29.5 31.7 35.9 24.1 14.3 35.6 10.9 30.0 18.6 14.2 23.0 40.3 19.0 9.0 20.0 22.0 13.2 31.4 22.2 14.6 29.6 14.5 20.6 12.2 29.6 29.9 21.2 40.0 11.9 26.4 38.1 13.8 27.0 28.0 0.3 0.1 0.2 0.2 0.0 0.0 0.4 0.2 0.2 0.1 0.2 0.0 0.1 0.3 0.7 0.0 0.3 0.3 0.1 0.8 0.8 0.7 1.2 0.8 0.6 0.7 0.6 0.8 0.4 0.8 1.0 1.6 3.2 0.5 2.0 2.4 0.9 0.6 2.0 1.2 1.1 2.8 3.0 0.5 0.0 2.3 0.0 4.2 2.5 1.6 5.4 0.0 1.6 1.6 7.8 3.2 2.2 1.8 12.8 5.1 0.4 4.4 1.6 3.1 12.4 2.5 8.2 1.4 0.5 2.9 0.0 3.9 6.1 0.0 2.4 1.2 1.1 0.3 2.7 0.0 0.0 3.0 0.8 1.0 2.0 4.8 1.9 1.8 0.7 10.2 1.1 1.4 0.4 7.6 0.6 0.0 1.7 2.0 17.8 14.4 5.3 2.4 0.8 3.3 2.6 5.5 1.4 SYCP1 "CT8, HOM-TES-14, SCP1" ENSG00000198765 "Synaptonemal complex protein 1" Q15431 1 114854863-114995370 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Meiosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 70 "testis: 40.2" "Cell type enriched" "Detected in some" 8 "Spermatocytes: 1162.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 98 "THP-1: 17.2" "Region enriched" "Detected in single" 51 "cerebellum: 14.7" "Not detected" "Not detected" HPA021083 Enhanced Approved "Nuclear bodies,Cytosol" NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 43: THP-1 - Innate immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nuclear bodies, Cytosol" "HPA021083: AB_1857685" "unprognostic (2.91e-1)" "unprognostic (6.89e-3)" "unprognostic (4.87e-1)" "unprognostic (8.74e-3)" 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 139.5 0.3 0.0 0.2 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 16.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 56.7 5.3 0.4 0.0 1.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 1162.6 32.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SYCP2 SCP2 ENSG00000196074 "Synaptonemal complex protein 2" Q9BX26 20 59863564-59933655 "Disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Meiosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 43.2" "Cell type enriched" "Detected in many" 5 "Spermatocytes: 468.5" "Group enriched" "Detected in many" 6 "breast cancer: 6.7;cervical cancer: 11.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 25.9;JURKAT: 47.2;MOLT-4: 54.4;SiHa: 92.2;T-47d: 82.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA062401, HPA065613" Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 78: Testis - Spermatogenesis" "Cluster 6: T47d - Mammary gland" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "Plasma membrane, Cytosol" "HPA062401: AB_2684752, HPA065613: AB_2685519" "unprognostic (8.10e-3)" "unprognostic (8.28e-3)" "unprognostic (1.62e-1)" "unprognostic (2.48e-2)" "unprognostic (1.57e-1)" "unprognostic (1.19e-3)" "unprognostic (2.50e-2)" "unprognostic (2.18e-1)" "unprognostic (4.11e-2)" "unprognostic (1.44e-1)" "unprognostic (3.74e-1)" "unprognostic (7.02e-3)" "unprognostic (4.84e-3)" "unprognostic (8.48e-2)" "unprognostic (2.46e-1)" "unprognostic (7.87e-3)" "unprognostic (1.21e-1)" 3.2 0.8 2.2 1.4 2.8 2.4 13.9 9.7 4.9 2.4 0.0 1.3 1.6 1.6 1.2 0.9 1.3 2.4 2.5 2.2 1.1 4.3 1.1 2.2 2.6 1.8 1.8 0.7 6.6 0.7 1.9 3.9 2.2 3.8 1.1 1.5 4.4 1.0 1.3 2.7 2.4 0.7 1.4 3.1 6.1 43.2 2.5 1.3 2.4 1.0 1.7 1.8 1.5 4.1 0.3 1.3 0.2 1.4 0.6 0.8 1.4 4.1 1.1 1.8 0.2 25.9 2.6 0.1 4.0 1.8 0.8 0.6 0.5 0.1 1.0 8.5 0.6 0.2 6.1 0.4 0.2 0.4 19.0 0.4 0.4 0.4 0.0 0.9 0.0 47.2 0.2 0.0 0.9 12.5 54.4 2.9 0.4 1.5 0.3 0.0 0.1 0.2 2.1 6.1 0.2 4.5 92.2 13.3 3.3 1.6 82.6 4.7 0.5 0.1 2.8 11.2 0.0 0.0 0.0 0.0 0.0 1.7 5.2 0.7 0.1 0.7 0.8 0.0 0.8 0.2 0.4 0.5 0.0 0.2 0.2 0.4 0.7 0.0 0.0 0.0 0.3 0.2 2.2 2.8 9.7 4.9 2.2 1.1 1.8 1.8 2.2 1.4 2.5 4.1 11.5 0.0 1.1 24.5 1.4 1.0 1.1 1.0 0.0 1.9 12.7 9.4 3.6 2.8 6.3 1.8 2.1 0.8 3.0 0.1 1.9 0.9 82.3 0.4 5.0 6.5 0.0 0.0 27.5 3.6 0.4 2.1 2.6 0.5 2.5 1.2 2.9 0.0 0.5 0.0 14.6 0.1 0.0 1.2 0.8 21.8 4.7 1.6 5.4 13.1 1.4 2.3 5.2 28.6 11.1 1.2 1.2 1.9 0.4 1.8 0.3 5.4 8.6 1.1 52.6 1.7 3.8 468.5 92.4 0.6 0.0 0.4 4.1 0.2 0.3 1.2 SYCP3 ENSG00000139351 "Synaptonemal complex protein 3" Q8IZU3 12 101728648-101739472 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Meiosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 146 "testis: 82.9" "Group enriched" "Detected in many" 8 "Spermatocytes: 825.7;Spermatogonia: 346.9" "Cancer enriched" "Detected in single" 16 "testis cancer: 5.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Karpas-707: 1.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB032978, HPA039635, HPA043938" Enhanced NA NA "Cluster 46: Basophils - DNA binding" "Cluster 74: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "CAB032978: AB_656732, HPA039635: AB_2676607, HPA043938: AB_2678740" "unprognostic (2.86e-3)" "unprognostic (3.91e-1)" "unprognostic (3.18e-1)" "unprognostic (9.61e-3)" "unprognostic (1.40e-1)" "unprognostic (1.22e-2)" "unprognostic (7.49e-2)" "unprognostic (1.65e-1)" "unprognostic (1.82e-1)" "unprognostic (2.86e-2)" "unprognostic (7.15e-3)" "unprognostic (7.81e-3)" "unprognostic (4.85e-2)" "unprognostic (1.93e-2)" "unprognostic (2.24e-1)" "unprognostic (4.07e-2)" "unprognostic (5.86e-4)" 0.0 0.1 0.3 0.3 0.4 0.2 0.0 0.5 0.3 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.1 82.9 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 1.3 0.2 0.0 0.3 0.2 0.0 0.1 0.0 0.0 0.2 0.6 0.4 0.2 0.0 0.1 0.0 0.0 0.5 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.5 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.0 2.0 9.1 4.5 0.0 0.7 0.4 1.2 2.2 0.9 0.6 1.3 1.5 0.3 1.8 0.0 0.4 3.1 0.6 0.0 0.1 24.1 0.3 1.3 0.9 1.2 0.4 10.1 0.4 0.2 0.7 0.0 0.7 3.8 0.3 0.7 0.2 0.6 0.0 10.7 0.7 0.0 1.0 0.3 31.2 9.0 1.7 0.0 0.0 0.4 0.3 1.0 9.5 1.8 0.3 1.9 1.9 2.0 0.9 1.0 0.3 0.8 1.7 65.7 2.0 0.4 825.7 346.9 0.7 0.3 0.1 2.0 0.2 1.3 0.5 TASOR "C3orf63, FAM208A, KIAA1105, RAP140, se89-1, TASOR1" ENSG00000163946 "Transcription activation suppressor" Q9UK61 3 56620133-56683237 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 25.0;Cardiomyocytes: 31.4;Cytotrophoblasts: 14.5;dendritic cells: 12.1;Extravillous trophoblasts: 9.9;Fibroblasts: 10.7;Hofbauer cells: 20.7;Syncytiotrophoblasts: 9.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006735, HPA017142" Uncertain Enhanced Nucleoplasm NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "HPA006735: AB_1852384, HPA017142: AB_1852382" "unprognostic (1.46e-1)" "unprognostic (7.97e-2)" "unprognostic (1.07e-2)" "unprognostic (1.79e-1)" "unprognostic (1.92e-1)" "unprognostic (2.51e-2)" "unprognostic (2.30e-3)" "unprognostic (9.31e-2)" "unprognostic (3.91e-2)" "unprognostic (5.93e-2)" "unprognostic (1.51e-1)" "unprognostic (8.84e-2)" "unprognostic (1.73e-1)" "unprognostic (1.90e-1)" "unprognostic (2.04e-1)" "unprognostic (1.67e-1)" "unprognostic (2.74e-1)" 9.5 8.4 4.0 15.4 8.4 11.8 11.4 8.7 5.3 12.0 1.7 11.7 10.0 12.3 7.4 11.1 13.1 11.7 6.2 2.2 3.6 10.2 7.9 11.3 20.7 5.1 5.6 14.2 12.4 21.1 4.4 9.4 6.0 9.3 12.4 9.9 8.9 9.4 2.6 7.1 11.3 12.3 5.9 14.7 12.8 29.2 4.5 21.3 18.8 6.9 19.3 12.5 3.8 12.0 49.2 19.2 29.2 23.0 15.5 26.7 14.6 21.4 22.0 20.1 21.1 15.8 35.8 77.3 7.9 21.6 33.9 19.1 29.3 25.1 29.2 38.3 14.8 30.4 27.3 7.1 10.9 32.2 46.1 12.9 20.6 19.6 35.1 23.7 26.5 28.8 29.8 43.3 26.0 17.3 39.8 6.4 16.3 25.9 29.0 20.9 28.9 25.9 19.0 35.5 19.3 23.9 46.9 18.5 23.2 16.6 30.6 36.7 28.6 25.9 23.7 23.8 33.1 39.2 58.5 38.6 30.1 46.7 35.0 0.6 0.8 1.1 1.2 0.6 0.7 0.7 1.0 1.2 1.0 1.1 1.1 1.2 0.2 0.9 0.7 0.7 1.0 0.6 4.0 8.4 8.7 5.3 2.2 3.6 5.1 5.6 6.0 5.9 4.5 12.0 25.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.4 0.0 0.0 0.0 0.0 14.5 12.1 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 9.9 10.7 0.0 0.0 0.0 0.0 0.0 0.0 20.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 9.2 2.1 0.0 0.0 0.0 TBCCD1 FLJ10560 ENSG00000113838 "TBCC domain containing 1" Q9NVR7 3 186546067-186570543 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 42.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "unprognostic (1.15e-1)" "unprognostic (7.41e-3)" "unprognostic (6.36e-2)" "unprognostic (2.62e-2)" "unprognostic (8.79e-2)" "unprognostic (7.14e-2)" "prognostic unfavorable (1.87e-4)" "unprognostic (2.10e-2)" "unprognostic (1.42e-2)" "unprognostic (2.72e-2)" "unprognostic (2.59e-3)" "unprognostic (1.14e-1)" "unprognostic (1.43e-1)" "unprognostic (2.91e-1)" "unprognostic (1.62e-1)" "unprognostic (1.15e-1)" "unprognostic (2.27e-1)" 6.7 5.9 4.7 7.5 5.6 7.5 6.7 6.4 5.3 6.4 6.8 6.5 6.4 7.1 7.5 7.7 5.7 6.2 5.4 4.5 5.6 6.2 9.5 5.4 9.4 5.3 5.3 6.3 7.5 8.5 4.2 7.6 5.8 5.2 7.3 12.5 6.4 5.3 6.1 6.9 6.1 6.3 5.3 6.6 6.1 19.2 5.3 10.9 8.4 7.4 9.2 6.6 6.5 6.8 12.5 8.7 13.8 13.7 11.6 12.4 9.8 9.5 6.9 12.2 12.9 15.3 9.6 15.3 24.5 6.9 9.5 13.2 21.3 9.0 15.6 22.2 10.9 19.5 7.7 9.5 6.6 18.4 12.7 7.4 9.5 10.8 12.5 8.0 17.3 19.9 15.9 14.3 10.8 15.0 17.9 10.6 8.6 28.4 15.1 20.3 13.8 17.1 8.0 7.7 16.2 10.4 17.0 18.9 10.1 10.8 24.7 11.6 10.7 8.4 10.7 10.5 15.0 19.8 36.9 37.0 9.0 16.4 16.5 17.3 9.7 11.7 11.7 9.7 15.3 11.8 12.9 13.2 12.8 11.3 10.2 13.0 4.2 14.6 11.3 7.5 18.0 9.1 4.7 5.6 6.4 5.3 4.5 5.6 5.3 5.3 5.8 5.3 5.3 6.8 5.6 16.0 3.7 8.5 8.8 6.4 2.8 2.6 9.1 6.5 3.2 2.4 2.6 4.3 1.9 1.8 2.1 4.0 2.9 4.1 11.7 7.1 3.0 3.7 4.9 5.3 3.6 5.9 11.5 6.5 6.0 4.7 12.2 3.5 12.0 4.2 6.8 5.2 4.7 0.0 13.2 6.6 0.0 3.8 6.4 2.8 5.9 4.2 5.4 7.5 4.6 5.2 9.2 12.5 14.1 4.8 5.0 3.8 11.5 2.2 5.4 3.5 7.0 6.7 6.6 4.2 4.8 42.1 20.8 9.7 4.1 4.1 7.2 3.3 5.5 1.9 TCTN2 "C12orf38, FLJ12975, JBTS24, MKS8, TECT2" ENSG00000168778 "Tectonic family member 2" Q96GX1 12 123671110-123708399 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation" "Ciliopathy, Joubert syndrome, Meckel syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 27.6;Respiratory ciliated cells: 32.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039900 Enhanced Approved "Golgi apparatus,Vesicles" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "Golgi apparatus, Vesicles" "HPA039900: AB_10673366" "unprognostic (3.46e-2)" "unprognostic (1.03e-1)" "unprognostic (1.30e-2)" "unprognostic (1.45e-2)" "unprognostic (1.63e-3)" "unprognostic (1.32e-1)" "unprognostic (3.09e-3)" "unprognostic (3.14e-2)" "unprognostic (7.05e-2)" "unprognostic (1.09e-1)" "unprognostic (3.97e-3)" "unprognostic (2.23e-1)" "unprognostic (1.69e-1)" "unprognostic (2.79e-1)" "unprognostic (2.46e-1)" "unprognostic (7.86e-2)" "unprognostic (2.68e-1)" 5.3 4.4 5.5 2.6 6.4 1.9 7.2 5.8 5.3 10.0 30.4 5.7 2.1 11.0 11.0 3.4 28.5 6.4 4.8 4.9 9.5 10.0 1.4 8.3 3.3 8.4 11.5 14.7 6.9 14.1 16.3 4.6 6.5 9.6 4.0 17.6 9.1 8.6 1.7 8.3 3.8 6.0 7.1 4.1 5.4 11.1 8.7 2.5 12.4 2.1 3.0 5.2 6.7 4.1 14.9 15.1 10.7 15.6 15.0 16.5 13.1 5.4 10.9 11.5 8.7 7.9 14.5 0.5 9.2 8.9 10.0 19.6 6.2 4.9 11.2 2.5 7.6 1.2 10.6 7.2 5.0 3.7 4.8 8.0 8.8 16.3 4.8 34.9 15.7 5.1 7.1 0.3 7.1 7.9 4.5 7.4 6.8 5.9 9.1 4.0 10.8 1.5 13.7 11.1 6.5 8.3 18.2 6.0 8.4 11.0 25.5 5.6 9.8 16.0 8.2 14.7 7.1 4.3 8.9 1.4 20.9 0.4 9.7 1.7 0.2 1.2 1.9 0.6 2.7 1.9 2.2 2.0 0.4 2.1 2.4 2.4 0.3 0.8 0.5 2.5 1.4 0.2 5.5 6.4 5.8 5.3 4.9 9.5 8.4 11.5 6.5 7.1 8.7 4.1 2.7 3.2 5.3 6.5 1.8 4.1 2.3 2.6 1.2 4.4 4.8 2.3 3.8 5.7 3.9 7.3 12.5 2.8 2.1 1.2 0.0 2.9 6.1 27.6 5.0 1.7 1.2 2.5 10.4 2.1 3.0 4.6 2.6 4.3 3.8 5.0 2.9 0.4 1.3 0.0 14.4 1.8 2.0 0.3 1.2 2.8 2.5 1.0 5.4 2.8 1.4 4.6 1.0 2.5 1.3 2.0 0.8 4.9 1.1 1.4 0.2 1.9 32.1 14.5 0.0 6.0 2.7 11.5 10.9 0.6 2.3 1.1 2.4 2.3 3.0 1.0 TDRD1 CT41.1 ENSG00000095627 "Tudor domain containing 1" Q9BXT4 10 114179270-114232304 "Plasma proteins, Predicted intracellular proteins" "Differentiation, Meiosis, RNA-mediated gene silencing, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "testis: 17.5" "Cell type enhanced" "Detected in some" "Early spermatids: 7.1;Late spermatids: 5.3;Spermatocytes: 25.6;Spermatogonia: 25.5" "Cancer enriched" "Detected in some" 5 "prostate cancer: 4.1" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.4" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 4 "SK-BR-3: 51.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA037729 Enhanced NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 83: Testis - Spermatogenesis" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "HPA037729: AB_10670527" "unprognostic (6.77e-2)" "unprognostic (2.73e-1)" "unprognostic (1.06e-1)" "unprognostic (1.68e-1)" "unprognostic (1.10e-2)" "unprognostic (1.26e-2)" "unprognostic (3.96e-2)" "unprognostic (3.15e-2)" "unprognostic (6.13e-2)" "unprognostic (1.55e-1)" "unprognostic (1.82e-1)" "unprognostic (1.51e-2)" "unprognostic (9.60e-2)" "unprognostic (3.98e-2)" "unprognostic (4.75e-1)" "unprognostic (1.68e-1)" 0.2 0.0 0.2 0.1 0.3 0.0 0.3 0.1 0.6 0.1 0.2 0.1 0.2 0.1 0.0 0.2 0.2 0.1 0.6 0.1 0.2 2.0 0.2 0.0 0.2 0.3 0.3 0.4 0.5 0.0 0.0 0.0 0.2 0.6 0.1 0.0 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.5 0.1 17.5 0.3 0.2 0.1 0.5 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.3 0.0 0.0 0.0 0.0 0.0 0.0 10.9 0.0 0.0 0.0 0.0 0.0 0.0 51.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.1 0.0 1.4 0.0 0.0 0.2 0.3 0.1 0.6 0.1 0.2 0.3 0.3 0.2 0.1 0.3 0.4 0.6 0.0 0.5 0.0 0.0 0.3 0.0 0.1 0.0 0.0 1.1 0.9 3.5 2.8 0.0 0.0 0.0 0.3 2.7 0.3 0.0 0.2 7.1 0.4 0.5 0.2 0.0 0.0 0.5 0.6 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 2.0 0.0 0.3 5.3 2.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.7 0.0 0.0 0.0 1.2 2.7 0.0 0.0 0.5 0.5 25.6 25.5 0.0 0.0 0.1 0.1 0.7 0.1 0.0 TDRD12 "ECAT8, FLJ13072" ENSG00000173809 "Tudor domain containing 12" Q587J7 19 32719753-32829580 "Enzymes, Predicted intracellular proteins" "Differentiation, Meiosis, RNA-mediated gene silencing, Spermatogenesis" "Developmental protein, Helicase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "epididymis: 7.3;testis: 16.7" "Cell type enhanced" "Detected in some" "Early spermatids: 24.0;Late spermatids: 12.0;Spermatocytes: 65.0;Spermatogonia: 43.5" "Cancer enriched" "Detected in many" 9 "testis cancer: 10.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 30 "HDLM-2: 25.5;NTERA-2: 81.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "unprognostic (5.43e-2)" "unprognostic (3.97e-1)" "unprognostic (1.14e-1)" "unprognostic (1.87e-7)" "unprognostic (5.44e-2)" "unprognostic (1.78e-1)" "unprognostic (6.79e-2)" "unprognostic (1.20e-1)" "unprognostic (2.07e-1)" "unprognostic (1.40e-1)" "unprognostic (9.69e-2)" "unprognostic (1.90e-1)" "unprognostic (1.43e-4)" "unprognostic (2.09e-1)" "unprognostic (4.75e-2)" "unprognostic (3.08e-2)" "unprognostic (2.69e-2)" 0.2 0.8 0.2 0.1 0.2 0.1 0.2 0.1 0.3 0.7 0.0 0.2 0.0 1.1 7.3 0.3 0.8 0.1 0.1 0.2 0.6 0.1 0.0 0.1 0.2 0.4 0.2 1.6 0.0 0.0 0.1 0.0 0.2 0.2 0.1 0.4 0.1 0.3 0.1 1.7 1.2 0.1 0.1 0.3 0.1 16.7 0.9 0.4 0.4 0.0 0.2 0.2 0.2 0.2 0.0 1.1 0.2 1.3 0.1 0.1 1.7 0.2 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.3 0.0 25.5 0.2 0.0 0.0 0.3 0.0 0.0 0.1 0.5 0.5 0.0 0.0 0.2 0.0 0.1 0.0 0.2 0.1 0.3 0.1 0.0 81.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.3 0.3 0.1 0.0 0.0 0.4 0.1 0.3 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.3 0.2 0.6 0.4 0.2 0.2 0.1 0.9 0.2 0.3 0.0 0.0 1.3 0.0 0.0 0.4 0.0 0.0 0.4 0.6 0.3 0.9 0.0 0.0 1.8 0.0 0.4 0.2 0.1 0.0 0.0 24.0 0.3 1.2 0.4 0.0 0.0 2.2 0.0 1.3 0.2 0.0 1.1 0.0 0.2 0.4 0.0 0.1 0.0 2.1 0.1 0.0 0.0 0.3 12.0 2.1 0.1 0.0 1.0 0.0 0.2 0.0 0.0 1.4 0.1 0.2 1.5 0.1 0.1 0.1 0.2 0.0 0.2 0.0 0.4 0.3 65.0 43.5 0.0 0.1 0.3 0.2 2.9 0.4 0.2 TDRD15 ENSG00000218819 "Tudor domain containing 15" B5MCY1 2 21123968-21144368 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "testis: 5.4" "Cell type enhanced" "Detected in some" "Early spermatids: 5.0;Late spermatids: 12.1;Sertoli cells: 6.6;Spermatocytes: 34.5;Spermatogonia: 8.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NB-4: 1.5;U-266/70: 7.5;U-266/84: 3.0" "HPA051770, HPA054675" Uncertain NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA051770: AB_2681601, HPA054675: AB_2682569" "unprognostic (4.20e-3)" "unprognostic (1.46e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.5 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 5.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 2.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 12.1 0.6 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.1 0.0 34.5 8.5 0.0 0.0 0.0 0.2 0.0 0.1 0.0 TDRD5 "FLJ34823, TUDOR3" ENSG00000162782 "Tudor domain containing 5" Q8NAT2 1 179591613-179691272 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 6.5;testis: 21.9" "Group enriched" "Detected in some" 4 "Early spermatids: 36.1;Late spermatids: 12.1;Spermatocytes: 26.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MCF7: 3.7;SK-BR-3: 5.8;T-47d: 10.3;U-266/70: 14.3;U-266/84: 13.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" HPA029418 Enhanced NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 29: Early spermatids - Spermatogenesis" "HPA029418: AB_10603035" "unprognostic (1.87e-1)" "unprognostic (1.43e-1)" "unprognostic (2.08e-1)" "unprognostic (2.15e-4)" "unprognostic (3.96e-1)" "unprognostic (4.39e-3)" "unprognostic (4.41e-4)" "unprognostic (3.18e-1)" "unprognostic (4.30e-1)" "unprognostic (3.75e-2)" "unprognostic (1.18e-1)" "unprognostic (3.37e-1)" "unprognostic (1.44e-2)" "unprognostic (1.28e-1)" "unprognostic (2.78e-2)" "unprognostic (6.89e-2)" "unprognostic (2.31e-1)" 0.2 0.3 0.8 0.1 1.4 0.3 3.6 0.0 0.8 0.1 0.0 0.6 0.5 0.0 6.5 0.5 0.9 0.2 0.0 0.7 0.4 1.8 0.0 0.1 0.0 0.9 0.9 0.0 0.2 0.3 2.3 0.2 1.0 0.6 0.7 0.3 0.8 0.3 0.0 0.3 0.4 0.0 0.6 0.0 0.3 21.9 1.1 0.1 0.8 0.0 0.4 0.3 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 3.7 0.0 0.0 1.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 5.8 0.0 0.7 10.3 0.2 0.0 0.0 1.5 0.0 0.0 14.3 13.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.4 0.0 0.8 0.7 0.4 0.9 0.9 1.0 0.6 1.1 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 3.5 1.8 0.7 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.1 36.1 1.0 0.0 0.1 0.0 0.0 5.2 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.9 0.0 0.0 0.0 12.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 1.1 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.4 5.7 0.0 0.3 0.0 0.0 0.0 0.3 0.1 TDRD6 "bA446F17.4, CT41.2, NY-CO-45, SPATA36" ENSG00000180113 "Tudor domain containing 6" O60522 6 46687875-46704319 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 30.3" "Group enriched" "Detected in many" 4 "Early spermatids: 224.8;Spermatocytes: 82.7" "Cancer enhanced" "Detected in some" "prostate cancer: 2.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HeLa: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA075923, HPA077353" Enhanced Approved "Vesicles,Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 21: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 29: Early spermatids - Spermatogenesis" "Microtubules, Cytokinetic bridge, Mitotic spindle" Vesicles "HPA075923: , HPA077353: " "unprognostic (2.01e-1)" "unprognostic (7.41e-3)" "unprognostic (7.25e-3)" "unprognostic (3.88e-2)" "unprognostic (3.54e-1)" "unprognostic (4.10e-2)" "unprognostic (1.03e-1)" "unprognostic (4.32e-2)" "unprognostic (7.97e-2)" "unprognostic (2.50e-1)" "unprognostic (2.20e-3)" "unprognostic (2.20e-1)" "unprognostic (2.79e-1)" "unprognostic (2.86e-1)" "unprognostic (2.00e-1)" "unprognostic (2.16e-2)" "unprognostic (4.38e-3)" 0.7 1.7 3.3 3.0 5.1 0.2 0.8 7.8 5.4 1.2 1.8 1.0 0.7 0.9 3.4 0.6 0.8 2.2 1.6 4.1 2.6 2.1 2.5 0.7 4.0 3.9 3.2 1.1 1.1 0.4 3.0 1.6 4.1 2.0 0.3 8.9 1.3 0.6 2.3 3.5 0.7 0.4 2.7 2.5 0.8 30.3 3.7 0.0 5.6 0.1 0.1 1.1 0.8 4.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.3 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.0 0.2 0.2 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 5.1 7.8 5.4 4.1 2.6 3.9 3.2 4.1 2.7 3.7 4.0 0.8 9.6 0.5 3.9 0.0 0.5 0.4 0.1 1.2 11.3 0.4 0.8 3.4 0.0 3.8 7.3 6.2 0.0 0.0 0.0 1.9 0.3 224.8 1.0 2.2 1.2 4.2 0.0 13.6 0.2 0.0 1.0 0.0 0.7 0.0 0.4 0.7 3.0 0.1 5.0 14.7 0.3 0.0 0.3 0.0 33.8 4.1 0.5 3.6 6.5 0.0 1.1 0.0 14.6 17.8 0.1 0.0 4.5 0.0 0.6 0.4 0.4 0.2 7.5 13.1 3.0 0.5 82.7 34.7 0.0 1.6 0.0 0.0 1.4 0.5 0.2 TDRD9 "C14orf75, DKFZp434N0820, FLJ36164, NET54" ENSG00000156414 "Tudor domain containing 9" Q8NDG6 14 103928456-104052667 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Differentiation, Meiosis, RNA-mediated gene silencing, Spermatogenesis" "Developmental protein, Helicase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "parathyroid gland: 30.6;testis: 40.7" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 43.2;Spermatocytes: 63.2;Spermatogonia: 38.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 6 "classical monocyte: 1.6" "Lineage enriched" "Detected in single" 6 "monocytes: 1.6" "Cell line enhanced" "Detected in some" "HDLM-2: 24.4;HeLa: 21.5;HMC-1: 94.2;RPTEC TERT1: 25.5;SK-MEL-30: 13.3" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 3: HMC-1 - Innate immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "unprognostic (3.71e-1)" "unprognostic (3.02e-1)" "unprognostic (1.59e-1)" "unprognostic (1.89e-1)" "unprognostic (1.91e-1)" "unprognostic (1.55e-1)" "unprognostic (2.74e-1)" "unprognostic (3.74e-1)" "unprognostic (1.55e-1)" "unprognostic (1.61e-1)" "unprognostic (2.13e-4)" "unprognostic (1.60e-2)" "unprognostic (4.57e-3)" "unprognostic (8.97e-2)" "unprognostic (3.34e-1)" "prognostic unfavorable (5.52e-4)" "unprognostic (2.41e-2)" 0.4 0.5 0.9 0.6 0.8 1.7 0.5 1.3 0.9 0.4 1.2 0.3 0.1 0.4 0.4 0.2 0.9 0.9 0.6 0.8 0.8 2.1 0.3 1.0 0.5 1.7 1.0 0.2 0.5 30.6 1.0 0.5 2.0 0.3 0.2 3.5 0.3 0.5 0.1 0.1 0.3 0.5 1.1 3.0 0.8 40.7 1.1 0.3 5.4 0.5 0.5 0.4 0.2 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.4 0.0 0.0 21.5 0.0 0.0 0.0 94.2 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 25.5 0.0 8.7 0.0 0.0 0.6 13.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.9 0.8 1.3 0.9 0.8 0.8 1.7 1.0 2.0 1.1 1.1 1.3 0.9 6.4 2.0 2.3 0.0 0.0 0.1 0.1 0.0 4.3 1.0 0.4 12.4 0.0 0.7 0.0 4.2 0.0 0.5 0.0 1.9 0.6 13.1 43.2 1.5 0.9 0.0 1.3 9.1 0.0 0.0 0.7 0.0 3.7 0.0 0.3 0.4 0.1 1.9 6.7 4.6 0.0 2.0 1.8 0.0 7.3 0.9 1.5 0.0 2.8 2.9 0.6 0.0 1.0 4.6 0.5 0.0 2.2 0.3 0.5 0.0 2.5 0.2 2.3 6.6 0.9 0.8 63.2 38.6 0.0 0.0 0.0 0.3 11.7 0.0 0.1 TEX101 "CT131, MGC4766, SGRG, SPATA44, TES101RP" ENSG00000131126 "Testis expressed 101" Q9BY14 19 43401496-43418597 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 117.7" "Cell type enriched" "Detected in some" 6 "Spermatocytes: 909.7" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in many" 5 "cerebral cortex: 21.5" "Immune cell enriched" "Detected in single" 557 "basophil: 55.7" "Lineage enriched" "Detected in single" 557 "granulocytes: 55.7" "Cell line enhanced" "Detected in single" "THP-1: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA041915, HPA042513" Enhanced "Secreted in male reproductive system" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 43: THP-1 - Innate immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA041915: AB_10795268, HPA042513: AB_10795507" "unprognostic (2.50e-2)" "unprognostic (5.67e-4)" "unprognostic (2.64e-1)" "unprognostic (6.89e-2)" "unprognostic (1.87e-1)" "unprognostic (5.78e-4)" "unprognostic (1.70e-1)" "unprognostic (2.84e-2)" "unprognostic (6.54e-2)" "unprognostic (4.06e-1)" "unprognostic (2.49e-2)" "unprognostic (1.67e-7)" "unprognostic (8.83e-2)" "unprognostic (2.24e-1)" "unprognostic (7.49e-2)" "unprognostic (7.04e-2)" 0.1 0.4 0.3 0.3 0.3 0.1 0.2 0.3 21.5 0.5 0.2 0.5 0.4 0.4 0.2 1.3 0.3 0.2 0.5 2.6 0.2 0.2 0.5 0.2 0.2 4.3 0.2 0.5 1.6 0.1 0.0 0.2 2.0 0.3 0.5 0.0 1.1 0.2 0.6 1.5 0.5 0.3 1.1 0.1 0.2 117.7 0.3 1.0 0.1 0.0 1.3 0.1 1.0 0.4 0.2 0.0 0.3 0.1 0.2 0.6 0.1 0.1 0.1 0.2 0.2 0.0 0.1 0.1 0.2 0.4 0.3 0.1 0.1 0.2 0.1 0.3 0.0 0.1 0.4 0.1 0.5 0.1 0.2 0.3 0.4 0.0 0.2 0.2 0.4 0.2 0.1 0.2 0.3 0.0 0.1 0.2 0.1 0.2 0.1 0.7 0.0 0.2 0.5 0.0 0.2 0.0 0.1 0.2 0.6 0.1 0.0 1.3 0.1 0.2 0.1 0.1 0.3 0.2 0.3 0.1 0.2 0.1 0.1 55.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.3 21.5 2.6 0.2 4.3 0.2 2.0 1.1 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.0 0.2 0.1 0.5 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 10.2 0.0 0.0 31.5 6.5 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 32.9 0.0 0.0 909.7 151.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TEX11 "MZIP4, Spo22, TGC1, TSGA3, ZIP4" ENSG00000120498 "Testis expressed 11" Q8IYF3 X 70528940-70908711 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Meiosis "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "pancreas: 58.8" "Cell type enhanced" "Detected in some" "Distal enterocytes: 20.1;Early spermatids: 14.7;Exocrine glandular cells: 9.7;Late spermatids: 28.0;Paneth cells: 12.5;Spermatocytes: 46.5;Spermatogonia: 30.0" "Cancer enhanced" "Detected in some" "renal cancer: 1.3;testis cancer: 1.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA002950 Approved NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 25: Pancreas - Digestion" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA002950: AB_1080249" "unprognostic (6.78e-3)" "unprognostic (3.57e-3)" "unprognostic (2.87e-3)" "unprognostic (7.77e-2)" "unprognostic (7.75e-3)" "unprognostic (2.14e-2)" "unprognostic (1.66e-1)" "unprognostic (1.28e-1)" "unprognostic (1.74e-1)" "unprognostic (8.30e-2)" "unprognostic (5.74e-3)" "unprognostic (2.88e-1)" "unprognostic (1.11e-2)" "unprognostic (1.53e-1)" "unprognostic (3.03e-1)" "unprognostic (3.48e-1)" "unprognostic (1.56e-2)" 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 3.9 1.4 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.4 0.0 58.8 0.0 0.0 0.2 0.0 0.1 1.5 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.9 0.5 11.6 0.0 0.1 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.5 0.0 0.0 0.0 0.0 0.0 20.1 0.0 0.0 14.7 0.1 0.0 0.2 1.2 0.0 2.6 9.7 0.0 1.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 2.2 0.8 0.0 0.0 0.3 28.0 0.6 0.1 0.0 0.0 0.6 0.0 0.0 2.0 1.9 0.5 12.5 0.7 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 46.5 30.0 0.0 0.1 0.0 0.0 0.1 1.5 0.0 TEX12 ENSG00000150783 "Testis expressed 12" Q9BXU0 11 112167372-112172556 "Predicted intracellular proteins" Meiosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 15 "retina: 8.6;testis: 20.7" "Cell type enriched" "Detected in some" 5 "Spermatocytes: 211.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-698: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA038289, HPA038290" Enhanced NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 77: Retina - Visual perception" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA038289: AB_10672742, HPA038290: AB_2675934" "unprognostic (1.49e-1)" "unprognostic (6.57e-2)" "unprognostic (1.01e-1)" "unprognostic (2.92e-2)" "unprognostic (1.07e-1)" "unprognostic (2.93e-3)" "unprognostic (2.03e-1)" "unprognostic (1.55e-1)" "unprognostic (1.26e-1)" "unprognostic (1.21e-1)" "unprognostic (2.91e-1)" "unprognostic (9.20e-4)" "unprognostic (1.71e-2)" "unprognostic (2.97e-1)" "unprognostic (6.54e-2)" "unprognostic (4.10e-2)" "unprognostic (3.16e-3)" 0.3 0.0 0.1 0.1 0.1 0.4 0.4 0.5 0.3 0.2 0.1 0.3 0.6 0.2 0.0 0.1 0.2 0.1 0.2 0.1 0.1 0.2 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.2 8.6 0.2 0.1 0.9 0.7 0.4 0.2 0.0 0.2 0.2 20.7 0.2 0.1 0.1 0.7 0.2 0.2 0.2 0.1 0.0 0.0 0.2 0.1 0.3 0.2 0.0 0.0 0.1 0.1 0.3 0.1 0.4 0.7 0.2 0.2 0.1 0.0 0.1 0.2 0.2 0.5 0.0 0.3 0.0 0.0 0.4 0.4 0.2 0.2 0.2 0.3 0.1 0.0 0.0 0.2 0.1 0.3 0.0 0.0 0.3 0.7 0.1 0.4 0.2 0.2 0.1 0.6 0.3 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.8 0.0 0.1 0.4 0.2 0.1 0.0 0.0 1.4 0.1 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.3 0.1 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.6 0.3 0.4 0.0 0.5 0.1 0.3 0.4 0.0 0.1 0.0 4.2 0.1 0.3 0.3 0.0 0.2 2.0 0.0 0.1 0.1 0.0 0.0 1.7 0.2 0.1 0.2 0.0 0.2 0.0 0.3 0.0 0.4 0.3 0.0 2.2 0.1 0.0 0.0 1.9 5.1 0.9 0.3 0.0 1.0 0.6 0.3 0.0 0.5 0.2 0.1 0.1 0.7 0.1 0.2 0.3 0.1 0.0 0.4 6.6 0.2 0.4 211.7 36.1 0.0 0.4 0.0 0.3 0.2 0.2 0.3 TEX14 CT113 ENSG00000121101 "Testis expressed 14, intercellular bridge forming factor" Q8IWB6 17 58556678-58692055 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "testis: 27.0" "Group enriched" "Detected in many" 4 "Early spermatids: 23.3;Spermatocytes: 56.4;Spermatogonia: 16.2" "Cancer enhanced" "Detected in some" "breast cancer: 0.9" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 6.3;Karpas-707: 7.9;MCF7: 3.3" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA030620, HPA077020" Enhanced Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Cytosol "Vesicles, Plasma membrane" "HPA030620: AB_10601598, HPA077020: AB_2732327" "unprognostic (1.21e-2)" "unprognostic (2.12e-1)" "unprognostic (2.06e-1)" "unprognostic (9.49e-2)" "unprognostic (2.48e-1)" "unprognostic (1.23e-2)" "unprognostic (1.10e-1)" "unprognostic (6.17e-2)" "unprognostic (2.07e-2)" "unprognostic (1.61e-3)" "unprognostic (2.67e-2)" "unprognostic (8.10e-2)" "unprognostic (1.76e-9)" "unprognostic (1.77e-1)" "unprognostic (2.54e-1)" "unprognostic (5.00e-3)" "unprognostic (5.88e-2)" 0.1 0.1 0.5 0.1 0.6 1.7 0.2 1.1 0.6 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.4 0.5 0.4 0.2 0.2 0.1 0.5 0.5 0.3 0.1 0.0 0.2 0.1 0.5 0.2 0.0 1.1 0.1 0.0 0.0 0.1 0.1 0.0 0.5 0.2 0.1 27.0 0.5 0.0 0.0 0.0 0.1 0.1 0.0 0.8 0.0 0.0 0.1 1.7 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.5 0.1 0.0 0.1 0.0 0.2 0.0 0.1 6.3 0.9 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.3 0.1 7.9 0.0 3.3 0.3 0.0 0.4 0.1 0.1 0.3 0.2 1.2 0.0 0.1 0.9 0.1 0.0 0.0 0.4 0.3 0.3 0.0 0.0 0.0 0.2 0.0 0.0 1.4 0.3 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 1.1 0.6 0.4 0.5 0.5 0.5 0.5 0.5 0.5 0.8 4.4 0.0 0.0 2.9 5.7 0.9 1.8 0.7 2.8 0.6 4.7 7.2 1.3 5.7 1.5 1.8 0.0 1.6 0.7 0.1 0.0 0.0 23.3 0.4 0.2 1.5 0.0 0.0 2.2 0.0 1.0 0.7 0.5 1.8 1.3 0.2 1.4 0.8 3.7 0.0 2.2 0.5 2.0 0.6 2.3 6.4 0.3 4.6 3.6 2.8 0.0 0.6 1.0 1.0 3.0 0.1 0.0 0.4 4.3 0.7 0.0 0.1 0.2 1.3 0.0 1.2 1.5 56.4 16.2 1.7 0.1 1.1 0.7 0.0 0.0 0.4 TOP2A TOP2 ENSG00000131747 "DNA topoisomerase II alpha" P11388 17 40388525-40417896 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Biological rhythms" "DNA-binding, Isomerase, Topoisomerase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 127.8;testis: 65.7" "Cell type enhanced" "Detected in many" "Erythroid cells: 216.8;Granulosa cells: 117.5;Spermatocytes: 621.2;Spermatogonia: 269.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "T-reg: 2.4" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basal ganglia: 4.2;white matter: 8.0" "Low region specificity" "Detected in some" "CAB002448, HPA006458, HPA026773" Enhanced Approved Supported Nucleoplasm,Nucleoli Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Nucleoli "CAB002448: AB_564035, HPA006458: AB_1858189, HPA026773: AB_1858190" "unprognostic (2.09e-1)" "unprognostic (1.24e-1)" "unprognostic (2.28e-3)" "unprognostic (9.42e-3)" "unprognostic (1.80e-1)" "unprognostic (1.52e-1)" "prognostic unfavorable (5.92e-6)" "prognostic unfavorable (4.99e-4)" "unprognostic (6.21e-3)" "unprognostic (2.09e-1)" "prognostic unfavorable (3.83e-5)" "unprognostic (5.03e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (7.46e-2)" "unprognostic (1.07e-1)" "unprognostic (2.18e-1)" "unprognostic (2.29e-1)" 2.2 2.5 0.2 20.0 0.2 42.0 5.4 0.1 0.7 5.0 1.1 17.8 18.1 3.9 0.3 29.0 1.5 2.6 1.2 0.2 0.2 1.2 2.8 4.1 40.3 0.2 0.8 1.0 0.9 0.3 0.3 15.9 0.5 1.4 19.8 0.1 4.3 0.5 0.3 15.3 17.0 7.6 0.2 9.9 8.9 65.7 1.1 127.8 1.9 0.2 42.5 6.0 9.6 0.4 212.6 275.6 343.1 158.0 16.8 33.9 76.3 283.3 151.5 255.0 224.2 130.5 157.6 339.4 140.1 96.7 152.7 326.5 266.8 113.5 339.5 182.7 177.8 224.8 167.9 216.7 1.6 318.4 228.6 7.4 9.2 179.8 181.4 55.1 136.3 216.5 247.5 225.8 279.2 72.6 372.3 209.6 143.0 152.4 108.3 310.7 531.9 141.3 61.6 133.3 201.6 144.6 229.3 281.4 89.4 198.2 236.9 143.2 90.3 167.0 233.2 195.5 276.7 128.4 154.9 290.7 94.3 214.9 285.0 0.2 0.0 0.0 0.2 0.0 0.0 0.6 0.3 0.3 0.1 0.1 0.0 0.0 0.1 1.4 0.1 0.0 2.4 0.4 0.2 0.2 0.1 0.7 0.2 0.2 0.2 0.8 0.5 0.2 1.1 0.4 1.0 0.0 2.0 0.3 17.4 11.7 3.7 15.0 2.2 0.0 18.7 17.1 1.3 2.8 5.8 0.0 0.0 72.9 6.1 19.8 0.0 0.8 20.3 12.7 15.8 9.3 0.0 216.8 0.2 0.0 92.4 23.3 23.0 10.0 0.0 117.5 20.7 5.4 83.5 0.0 0.1 34.2 18.3 33.9 13.2 19.1 4.7 14.1 1.8 0.0 2.6 0.0 3.1 0.0 0.1 0.3 3.5 1.9 31.3 3.1 3.4 0.1 1.8 0.0 72.3 0.5 19.5 621.2 269.6 45.1 6.1 8.9 14.8 4.3 61.0 6.9 TOP3A "TOP3, ZGRF7" ENSG00000177302 "DNA topoisomerase III alpha" Q13472 17 18271428-18315007 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA-binding, Isomerase, Topoisomerase" "Cancer-related genes, Disease variant, Dwarfism, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 39.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB002449 Approved NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "CAB002449: AB_564037" "unprognostic (5.49e-2)" "unprognostic (9.04e-2)" "unprognostic (8.99e-2)" "unprognostic (7.24e-3)" "unprognostic (4.01e-2)" "unprognostic (1.95e-2)" "unprognostic (2.33e-3)" "unprognostic (6.54e-2)" "unprognostic (2.34e-1)" "unprognostic (2.74e-1)" "prognostic favorable (1.39e-4)" "prognostic unfavorable (4.59e-4)" "unprognostic (5.58e-2)" "unprognostic (8.80e-2)" "unprognostic (3.53e-2)" "unprognostic (5.05e-2)" "unprognostic (6.05e-2)" 9.4 8.0 1.9 3.3 1.8 5.7 8.6 3.1 2.6 8.6 2.1 7.8 2.3 8.4 1.6 8.6 8.5 2.1 6.0 1.8 1.8 7.0 11.2 7.7 3.6 1.7 1.6 7.5 7.7 2.6 8.9 2.5 1.7 7.7 2.4 2.1 8.1 1.7 10.0 11.3 8.2 2.6 1.4 11.4 7.6 11.7 2.0 4.2 6.7 2.5 3.3 8.5 7.8 2.0 9.3 14.2 9.4 11.1 3.8 4.6 10.9 9.4 4.9 14.2 12.8 22.4 3.4 13.7 6.0 6.5 6.6 11.7 12.6 6.7 11.5 11.6 11.4 13.1 15.2 7.9 4.3 5.8 11.9 2.9 4.6 15.0 8.7 2.9 7.3 11.5 11.3 5.7 6.1 6.4 15.2 5.9 8.7 13.8 6.8 17.4 22.6 14.8 3.2 8.1 7.7 13.6 12.6 8.3 8.4 24.5 16.1 6.5 6.5 10.6 8.1 18.2 15.4 5.8 13.7 10.4 6.6 8.0 10.5 1.1 3.1 3.4 1.8 2.7 1.3 0.7 1.3 1.6 1.3 0.8 1.1 1.2 4.2 2.2 1.5 1.2 1.2 2.0 1.9 1.8 3.1 2.6 1.8 1.8 1.7 1.6 1.7 1.4 2.0 2.0 5.3 6.4 4.8 6.5 9.7 2.0 4.5 4.5 6.8 20.8 6.2 3.9 3.1 5.7 7.4 11.0 39.6 7.4 11.8 4.6 3.9 4.2 7.2 5.0 8.7 6.2 0.0 9.9 16.4 3.7 6.9 6.3 6.6 6.3 5.1 12.1 6.4 7.0 5.4 21.9 17.2 4.2 4.1 12.4 6.3 7.9 8.1 11.6 1.8 12.2 13.9 6.4 15.5 11.6 11.2 3.6 2.8 6.4 12.0 5.8 3.8 2.1 6.5 22.2 13.1 9.3 6.6 26.7 25.5 5.2 3.4 4.4 9.0 13.1 5.9 5.0 TPST1 TANGO13A ENSG00000169902 "Tyrosylprotein sulfotransferase 1" O60507 7 66205317-66420543 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 76.5;Excitatory neurons: 101.9;Inhibitory neurons: 107.1;Spermatocytes: 97.1" "Cancer enhanced" "Detected in all" "glioma: 36.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 52.2;neutrophil: 35.2" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047415, HPA061837" Approved Supported "Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus" "HPA047415: AB_10964056, HPA061837: AB_2732672" "unprognostic (7.46e-2)" "unprognostic (1.45e-1)" "unprognostic (8.62e-2)" "unprognostic (3.43e-2)" "unprognostic (3.52e-2)" "unprognostic (1.78e-3)" "unprognostic (5.71e-2)" "unprognostic (8.21e-2)" "unprognostic (3.59e-1)" "unprognostic (9.25e-3)" "unprognostic (4.12e-2)" "unprognostic (4.98e-1)" "prognostic unfavorable (8.16e-6)" "prognostic unfavorable (8.78e-4)" "unprognostic (2.48e-1)" "unprognostic (1.74e-2)" "prognostic unfavorable (3.73e-5)" 16.9 15.8 22.1 10.8 20.5 6.0 13.4 18.4 21.6 35.4 12.3 11.1 3.2 21.8 14.3 10.8 11.2 38.1 8.5 19.4 36.7 23.1 46.0 11.5 5.9 37.2 25.0 13.5 7.8 11.0 19.5 26.4 24.7 15.1 8.0 5.2 6.8 16.4 2.7 8.2 8.7 16.2 22.9 12.0 10.9 23.0 33.8 2.1 11.3 5.6 5.3 36.8 22.1 22.5 12.1 6.5 16.5 22.4 52.7 42.0 5.7 22.3 49.8 25.7 37.1 21.9 6.6 1.4 17.7 45.1 38.9 8.9 16.2 24.8 33.3 3.5 9.3 2.3 15.1 16.5 62.3 1.8 1.9 59.5 19.0 50.2 22.1 27.8 32.7 2.9 1.0 10.2 40.2 6.2 0.1 3.1 15.5 0.4 9.6 7.8 14.6 11.4 27.3 11.5 10.4 44.5 27.8 2.1 62.2 32.4 8.6 4.7 62.3 33.1 21.3 24.2 40.6 9.2 13.3 4.7 29.6 6.8 48.2 52.2 2.3 23.9 0.8 0.1 0.8 6.1 0.5 0.6 0.3 14.0 2.2 4.1 35.2 8.8 0.0 0.0 0.0 1.9 22.1 20.5 18.4 21.6 19.4 36.7 37.2 25.0 24.7 22.9 33.8 22.5 33.8 0.0 8.9 38.8 11.5 10.8 7.7 24.4 33.6 8.5 4.0 13.3 1.6 5.7 9.6 31.3 2.1 1.8 3.8 0.2 9.8 23.0 11.2 13.3 76.5 17.9 7.7 1.3 101.9 47.6 4.3 58.5 12.2 9.7 4.5 12.2 10.0 34.1 16.2 6.7 107.1 0.8 8.2 8.9 8.9 11.6 48.1 6.2 14.2 32.8 15.8 5.0 1.0 61.3 38.8 23.7 0.1 37.2 7.1 5.3 0.0 3.2 19.5 3.6 6.6 16.4 21.6 97.1 41.3 15.1 7.5 3.8 2.8 12.6 0.7 7.7 TPTE "CT44, PTEN2" ENSG00000274391 "Transmembrane phosphatase with tensin homology" P56180 21 10521553-10606140 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 201 "testis: 107.2" "Cell type enriched" "Detected in some" 6 "Spermatocytes: 464.7" "Cancer enriched" "Detected in single" 7 "testis cancer: 0.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 6.7;K-562: 8.2;Karpas-707: 6.4;MCF7: 4.9;PC-3: 4.8;RPMI-8226: 9.0;SuSa: 7.6;U-266/70: 7.7" "HPA049690, HPA068342" Enhanced Approved "Endoplasmic reticulum,Cytosol" NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Cytosol "Endoplasmic reticulum" "HPA049690: AB_2680850, HPA068342: AB_2685976" "unprognostic (3.63e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 107.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 6.4 0.0 4.9 0.0 0.0 1.0 0.0 4.8 0.0 0.0 9.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 7.6 0.0 0.0 0.0 1.8 4.1 2.1 0.0 7.7 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 20.6 0.1 0.0 0.1 0.0 0.0 0.7 0.0 1.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.3 13.9 5.0 0.1 0.0 1.9 0.0 0.0 0.0 0.5 0.3 0.0 0.0 2.6 0.0 0.0 0.0 0.4 0.0 0.0 13.1 0.0 0.0 464.7 69.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 TPX2 "C20orf1, C20orf2, DIL-2, p100" ENSG00000088325 "TPX2 microtubule nucleation factor" Q9ULW0 20 31739271-31801805 "Cancer-related genes, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Mitosis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 48.0;lymphoid tissue: 70.3;testis: 30.7" "Cell type enhanced" "Detected in many" "Erythroid cells: 90.7;Extravillous trophoblasts: 68.5;Granulosa cells: 46.6;Spermatocytes: 114.5;Spermatogonia: 63.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "T-reg: 8.1" "Group enriched" "Detected in many" 5 "granulocytes: 5.1;NK-cells: 3.6;T-cells: 8.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005487 Enhanced Supported "Nucleoplasm,Cytokinetic bridge,Mitotic spindle" Yes Yes "Cluster 44: Non-specific - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Cytokinetic bridge, Mitotic spindle" "HPA005487: AB_1858223" "unprognostic (2.18e-2)" "unprognostic (1.77e-1)" "unprognostic (1.97e-2)" "prognostic unfavorable (2.43e-6)" "unprognostic (2.99e-1)" "unprognostic (7.56e-2)" "prognostic unfavorable (8.07e-7)" "prognostic unfavorable (6.46e-4)" "unprognostic (3.70e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (2.68e-5)" "unprognostic (5.99e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (4.56e-2)" "unprognostic (2.30e-1)" "unprognostic (1.76e-2)" "unprognostic (1.39e-1)" 1.9 1.4 0.9 13.0 0.9 48.0 2.7 0.8 1.0 2.3 0.5 11.6 9.4 2.4 0.2 13.2 0.9 1.8 0.8 1.1 0.6 0.7 4.2 1.9 26.6 0.6 1.0 0.5 0.4 0.4 0.2 8.3 0.7 0.7 14.2 0.5 2.0 0.5 1.4 9.8 9.4 6.8 0.6 5.2 6.2 30.7 1.3 70.3 1.0 0.8 32.3 3.4 4.1 0.9 455.1 149.1 176.4 139.1 13.8 25.2 169.8 186.1 104.5 264.0 197.7 319.1 190.4 212.4 106.7 104.5 196.8 232.7 203.7 169.0 298.8 92.3 78.8 416.3 139.7 219.6 4.2 161.9 102.8 8.7 9.1 166.0 120.0 37.9 144.6 157.1 313.8 187.8 209.7 186.2 272.2 125.3 197.1 174.0 159.3 152.5 475.5 128.2 71.2 72.8 127.5 85.7 284.6 106.3 82.0 120.9 185.1 97.3 98.3 294.1 179.7 136.5 290.0 74.4 138.6 187.3 92.2 565.1 195.8 5.1 0.0 0.4 0.4 0.0 0.2 0.6 1.4 1.7 0.5 0.2 0.3 0.5 0.2 3.6 0.1 1.0 8.1 1.0 0.9 0.9 0.8 1.0 1.1 0.6 0.6 1.0 0.7 0.6 1.3 0.9 1.0 0.0 4.2 0.0 5.9 6.9 1.5 4.3 1.2 0.9 3.0 3.4 0.9 4.3 3.8 0.0 0.0 23.3 3.8 6.4 0.0 1.2 9.3 7.3 6.6 3.9 1.2 90.7 2.9 0.4 68.5 9.2 16.3 8.4 0.0 46.6 8.9 3.0 19.5 1.7 0.9 9.8 10.2 8.0 5.5 13.1 0.9 7.6 0.0 1.0 2.1 0.4 3.1 0.5 0.5 1.8 1.4 0.0 30.8 2.5 0.9 0.0 0.7 0.4 0.0 1.1 15.4 114.5 63.1 31.2 6.1 4.7 8.2 4.2 18.4 2.9 TRAFD1 FLN29 ENSG00000135148 "TRAF-type zinc finger domain containing 1" O14545 12 112125538-112153604 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 117.6;Spermatocytes: 75.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039254, HPA039266" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 3: Monocytes - Immune response regulation" Nucleoplasm Cytosol "HPA039254: AB_10805358, HPA039266: AB_10795142" "unprognostic (7.80e-2)" "prognostic favorable (5.73e-4)" "unprognostic (6.12e-2)" "unprognostic (1.44e-1)" "unprognostic (9.46e-2)" "unprognostic (2.51e-2)" "prognostic unfavorable (4.87e-4)" "unprognostic (1.21e-3)" "unprognostic (1.69e-1)" "unprognostic (1.78e-1)" "unprognostic (3.09e-1)" "unprognostic (2.20e-1)" "prognostic unfavorable (9.26e-6)" "unprognostic (1.07e-1)" "unprognostic (6.15e-2)" "unprognostic (3.33e-3)" "prognostic favorable (3.92e-5)" 17.1 14.6 15.9 30.4 21.5 30.1 20.3 21.2 18.9 21.2 24.7 40.6 16.7 16.8 15.6 32.0 15.4 17.7 22.3 15.1 17.3 15.7 13.5 26.3 37.1 22.4 20.0 18.7 11.8 15.7 11.7 19.0 23.0 22.0 20.6 18.7 19.0 19.8 12.9 35.9 20.3 25.9 20.5 31.3 17.2 29.1 20.1 32.6 13.8 11.4 40.4 29.9 21.7 30.2 23.8 26.2 41.8 40.8 28.8 27.3 22.1 27.2 38.8 36.5 29.4 29.5 21.9 27.4 22.6 28.9 15.7 49.0 42.0 26.3 24.2 47.3 40.1 44.4 37.7 16.3 50.0 27.1 67.7 34.4 43.5 27.1 35.7 37.2 32.6 16.6 50.1 16.9 23.6 41.2 31.5 39.0 35.4 27.8 31.8 43.8 25.6 46.8 24.3 89.5 36.4 27.3 57.4 55.7 15.1 30.8 35.8 38.7 22.1 17.2 12.2 17.1 14.3 40.3 36.2 29.3 18.5 21.6 19.1 323.7 96.1 226.1 45.1 86.8 30.1 56.7 43.1 40.3 50.1 60.2 39.4 36.6 188.2 70.8 93.1 33.5 63.7 101.2 15.9 21.5 21.2 18.9 15.1 17.3 22.4 20.0 23.0 20.5 20.1 30.2 10.7 19.2 13.1 6.8 12.4 12.2 7.4 18.5 30.7 7.0 14.7 11.8 10.9 5.7 18.9 12.9 25.0 20.1 8.5 15.4 5.9 21.3 1.7 9.0 14.3 11.3 15.6 9.0 8.4 20.8 15.6 15.1 15.3 7.5 12.0 10.0 7.9 5.7 14.8 15.2 12.2 10.3 30.5 11.9 9.9 3.7 11.8 14.0 7.2 7.5 117.6 9.9 19.6 10.6 28.6 25.8 15.5 12.8 8.7 22.7 13.0 6.3 10.2 10.9 0.0 5.6 8.8 75.6 36.0 22.0 15.2 26.4 14.0 10.0 9.4 14.4 TRAPPC10 "EHOC-1, TMEM1, TRS130" ENSG00000160218 "Trafficking protein particle complex 10" P48553 21 44012309-44106552 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 81.2;Oligodendrocytes: 132.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 11 "basophil: 9.7" "Lineage enriched" "Detected in single" 13 "granulocytes: 9.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050423 Supported NA NA "Cluster 34: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 63: NK-cells & T-cells - Immune response" "HPA050423: AB_2681123" "unprognostic (1.82e-2)" "unprognostic (4.89e-3)" "unprognostic (3.52e-2)" "unprognostic (2.72e-1)" "unprognostic (3.79e-1)" "unprognostic (2.95e-3)" "unprognostic (1.93e-1)" "unprognostic (4.00e-1)" "unprognostic (9.70e-2)" "unprognostic (3.07e-3)" "unprognostic (2.60e-1)" "unprognostic (2.23e-1)" "unprognostic (3.02e-2)" "unprognostic (1.54e-1)" "unprognostic (1.41e-1)" "unprognostic (5.80e-2)" "unprognostic (2.76e-1)" 5.6 4.3 2.8 7.3 5.7 17.4 4.6 4.1 4.7 4.9 3.5 7.0 5.3 5.1 7.8 5.6 5.3 5.4 4.8 3.1 4.2 7.0 6.1 5.8 10.0 4.6 4.8 3.6 5.0 7.5 3.4 6.0 5.5 3.8 7.4 6.1 5.3 4.1 6.2 5.5 6.7 5.3 3.5 7.5 6.8 7.6 4.8 10.1 7.0 5.6 11.9 5.3 4.2 10.5 12.1 5.8 8.7 6.0 15.7 8.0 8.7 10.8 10.7 10.9 11.5 12.8 6.8 15.1 3.6 10.5 20.7 5.6 8.5 11.7 16.0 9.8 8.2 20.7 6.2 4.8 7.2 14.0 12.1 6.3 12.4 14.0 11.0 8.3 12.3 9.3 15.4 15.7 18.4 8.6 8.0 6.7 10.1 8.8 8.8 8.9 5.7 12.4 6.1 8.2 12.4 7.2 9.8 10.8 10.1 4.5 5.9 11.9 12.9 11.2 7.6 12.8 10.5 14.8 14.3 10.8 6.9 13.2 8.7 9.7 0.4 0.9 0.6 0.6 0.1 0.3 0.7 0.6 0.3 0.5 0.3 0.5 0.8 0.4 0.7 0.7 0.0 0.2 2.8 5.7 4.1 4.7 3.1 4.2 4.6 4.8 5.5 3.5 4.8 10.5 17.1 0.0 3.6 26.1 28.9 16.6 12.5 6.9 4.6 29.2 12.0 9.4 10.0 4.3 5.5 12.9 39.6 4.2 81.2 25.1 9.8 1.8 14.3 19.7 20.2 10.6 8.3 4.2 35.8 2.2 4.3 9.5 10.2 29.8 8.2 11.7 10.4 11.1 7.5 18.5 33.3 11.0 10.2 9.4 19.1 33.8 7.8 17.6 12.4 32.8 10.3 11.3 65.9 24.6 132.9 4.8 15.7 7.2 28.0 13.1 7.9 12.4 12.0 39.4 0.0 17.4 13.1 25.4 20.6 5.5 23.3 7.7 37.0 23.1 11.5 19.5 TRIM60 "FLJ35882, RNF129, RNF33" ENSG00000176979 "Tripartite motif containing 60" Q495X7 4 165016458-165041749 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "placenta: 1.5;testis: 1.5" "Group enriched" "Detected in some" 4 "Cytotrophoblasts: 5.1;Early spermatids: 3.0;Extravillous trophoblasts: 10.6;Spermatocytes: 9.6;Spermatogonia: 8.2;Syncytiotrophoblasts: 5.6" "Cancer enriched" "Detected in single" 103 "testis cancer: 5.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "BEWO: 14.2" "Not detected" "Not detected" "HPA035809, HPA035810, HPA061496" Uncertain Uncertain Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoli "Nucleoplasm, Cytosol" "HPA035809: AB_2674794, HPA035810: AB_10601827, HPA061496: AB_2684540" "unprognostic (1.10e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 14.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.3 0.2 0.3 0.2 0.3 0.0 0.4 0.5 0.9 0.7 0.0 0.1 0.0 0.0 5.1 0.6 0.0 0.0 0.0 3.0 0.8 0.9 0.7 0.0 0.0 0.2 0.0 10.6 0.3 0.0 1.5 0.0 0.2 0.0 1.1 0.5 0.0 0.3 0.0 0.0 1.3 0.0 0.5 0.9 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.4 0.7 0.3 0.0 0.1 0.8 0.5 0.0 0.0 0.3 9.6 8.2 0.0 0.3 5.6 0.7 0.2 0.0 0.1 TXNRD3 "TGR, TR2, TR2IT1, TRXR3, TXNRD3IT1, TXNRD3NB, TXNRD3NT1" ENSG00000197763 "Thioredoxin reductase 3" Q86VQ6 3 126571779-126655124 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Differentiation, Electron transport, Spermatogenesis, Transport" "Developmental protein, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 20.4" "Cell type enhanced" "Detected in many" "Spermatocytes: 71.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD4 T-cell: 1.0" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020802, HPA036109" Uncertain Enhanced Nucleoplasm,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm Cytosol "CAB020802: , HPA036109: AB_2674945" "unprognostic (1.41e-1)" "unprognostic (1.55e-2)" "unprognostic (3.92e-1)" "prognostic unfavorable (3.35e-4)" "unprognostic (3.90e-1)" "unprognostic (2.96e-1)" "unprognostic (3.01e-1)" "unprognostic (3.39e-2)" "unprognostic (1.07e-1)" "unprognostic (1.03e-1)" "prognostic unfavorable (2.86e-4)" "unprognostic (3.14e-1)" "prognostic favorable (2.72e-4)" "unprognostic (5.94e-2)" "unprognostic (1.74e-1)" "unprognostic (1.03e-2)" "unprognostic (2.51e-1)" 4.9 4.0 2.4 2.2 2.4 1.1 6.1 3.4 1.9 4.7 3.1 2.4 1.3 5.1 5.9 4.8 3.6 3.6 3.1 1.8 3.3 5.7 8.7 4.2 1.1 2.8 3.0 6.7 6.3 8.2 1.7 2.9 2.8 3.8 3.0 1.9 3.7 4.1 5.6 3.2 1.4 4.9 3.0 2.6 3.6 20.4 3.0 4.6 6.1 5.8 1.4 3.2 1.9 2.8 16.0 3.8 4.9 8.3 8.7 13.1 2.7 6.7 5.8 5.4 7.4 7.6 8.7 0.0 8.5 9.7 3.4 6.4 6.3 7.1 6.4 0.0 5.1 1.5 3.7 5.9 7.8 6.4 0.6 13.1 5.9 1.8 12.1 7.0 3.8 5.2 3.7 0.0 9.0 12.2 1.4 3.4 7.3 4.3 3.4 0.5 4.2 2.6 6.0 8.0 8.9 5.1 19.9 5.7 10.3 3.7 8.0 2.6 6.9 6.8 1.8 9.3 3.3 4.0 1.9 0.0 3.5 2.2 5.6 0.0 0.2 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.2 0.0 1.0 0.3 0.0 0.2 0.0 0.0 0.0 0.1 2.4 2.4 3.4 1.9 1.8 3.3 2.8 3.0 2.8 3.0 3.0 2.8 1.3 3.2 7.2 14.4 0.4 1.0 5.7 1.6 6.2 2.0 2.9 2.4 4.1 4.3 3.0 3.7 2.1 9.4 0.1 0.5 3.9 5.1 18.2 1.5 4.0 1.7 4.2 3.0 7.5 3.8 5.4 5.3 4.1 1.0 5.7 6.1 2.9 8.0 2.9 0.0 5.8 2.4 0.0 0.8 0.7 4.0 4.7 1.0 0.0 3.7 0.0 3.2 0.0 11.1 4.7 3.8 0.3 8.6 0.1 5.5 0.1 4.5 3.3 0.9 0.0 5.7 2.8 71.5 18.2 6.1 0.6 7.3 0.6 6.6 1.5 3.2 UHRF1 "FLJ21925, ICBP90, Np95, RNF106, TDRD22" ENSG00000276043 "Ubiquitin like with PHD and ring finger domains 1" Q96T88 19 4903080-4962154 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair, Transcription, Transcription regulation, Ubl conjugation pathway" "Chromatin regulator, DNA-binding, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "bone marrow: 27.0;lymphoid tissue: 67.2" "Cell type enhanced" "Detected in many" "Erythroid cells: 49.7;Plasma cells: 21.0;Squamous epithelial cells: 15.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 4.8" "Group enriched" "Detected in many" 4 "dendritic cells: 4.8;T-cells: 2.3" "Cell line enhanced" "Detected in all" "MOLT-4: 450.9;REH: 1004.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA049408, HPA055446" Enhanced Supported Nucleoplasm No Yes "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 14: REH - Unknown function" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA049408: AB_2756317, HPA055446: AB_2732597" "unprognostic (3.83e-2)" "unprognostic (6.83e-3)" "unprognostic (5.13e-2)" "unprognostic (1.69e-1)" "unprognostic (1.40e-1)" "unprognostic (7.21e-2)" "prognostic unfavorable (1.63e-4)" "unprognostic (4.30e-2)" "prognostic unfavorable (6.81e-4)" "unprognostic (2.82e-1)" "prognostic unfavorable (4.52e-5)" "unprognostic (2.33e-3)" "unprognostic (0.00e+0)" "unprognostic (3.75e-3)" "unprognostic (2.45e-1)" "unprognostic (2.01e-1)" "unprognostic (2.02e-1)" 1.0 0.9 2.1 9.6 2.7 27.0 1.7 2.1 2.3 1.6 1.8 2.9 3.7 1.0 0.1 6.5 0.4 0.8 0.5 2.0 2.2 0.6 0.9 1.3 15.8 2.8 2.8 0.3 0.6 0.2 0.2 2.1 2.7 0.6 2.6 0.4 1.5 0.2 1.2 3.4 3.9 1.9 1.9 3.7 3.3 5.2 3.5 67.2 0.3 0.3 10.3 1.6 2.5 4.6 111.3 78.7 116.6 83.4 3.3 13.3 18.5 88.3 42.0 89.9 86.8 94.6 54.9 62.7 21.1 39.4 32.7 54.1 81.2 47.7 63.0 102.7 92.2 54.3 74.3 102.4 1.3 135.1 78.9 6.5 3.5 48.9 12.6 14.1 27.2 97.2 79.3 70.5 54.5 86.7 450.9 82.5 52.5 40.0 84.3 1004.5 259.7 45.4 24.9 80.1 86.0 68.5 69.2 37.7 12.1 18.8 68.2 127.6 34.2 94.6 76.7 124.3 108.3 29.8 33.1 183.5 54.8 129.7 123.3 0.3 0.2 0.1 0.6 0.0 0.0 0.2 0.8 1.0 1.3 0.1 0.2 0.8 0.8 0.5 0.2 4.8 2.3 0.6 2.1 2.7 2.1 2.3 2.0 2.2 2.8 2.8 2.7 1.9 3.5 4.6 0.2 0.0 0.0 1.6 2.1 0.0 0.8 0.0 3.4 2.5 4.4 2.8 4.3 1.5 0.6 0.0 0.0 6.6 6.9 2.6 0.0 2.2 2.9 1.3 1.8 2.2 0.0 49.7 0.4 0.4 7.8 4.7 8.6 2.4 0.0 10.4 0.4 0.7 8.9 3.3 0.4 2.3 0.0 1.9 0.0 1.8 0.6 3.8 0.0 0.0 2.0 0.6 1.0 3.0 1.3 4.2 1.9 0.4 21.0 0.6 1.4 0.2 0.7 0.7 0.0 1.2 6.1 6.1 11.9 15.8 0.0 1.4 3.7 1.5 8.3 1.3 URB2 "KIAA0133, NET10, NPA2" ENSG00000135763 "URB2 ribosome biogenesis homolog" Q14146 1 229626247-229660200 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 29.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008902, HPA046788" Uncertain Enhanced Nucleoli NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoli "HPA008902: AB_2213805, HPA046788: AB_2679807" "unprognostic (1.26e-1)" "unprognostic (4.03e-3)" "unprognostic (2.16e-2)" "unprognostic (3.63e-2)" "unprognostic (1.79e-1)" "unprognostic (2.48e-1)" "unprognostic (5.53e-3)" "unprognostic (1.67e-1)" "unprognostic (1.02e-1)" "unprognostic (1.17e-1)" "unprognostic (1.59e-1)" "unprognostic (2.61e-2)" "unprognostic (1.62e-3)" "unprognostic (7.81e-2)" "unprognostic (2.72e-1)" "unprognostic (1.69e-2)" "unprognostic (1.45e-1)" 4.9 2.8 2.2 3.9 2.6 4.5 3.2 2.6 2.4 2.1 1.9 2.6 2.2 3.2 1.8 3.7 2.8 2.6 2.6 2.0 2.3 2.2 2.8 2.1 4.5 2.6 2.7 2.9 4.7 2.5 4.3 3.3 2.5 2.0 2.4 2.6 2.3 1.8 6.9 3.0 2.5 3.3 2.6 3.0 2.7 5.7 2.5 4.6 2.2 4.5 4.7 4.9 2.2 3.1 13.6 20.1 12.8 17.2 7.9 6.5 39.1 10.6 6.6 16.1 12.1 20.1 10.4 28.0 11.9 7.6 8.6 18.3 32.0 13.0 14.6 13.8 30.4 17.5 16.8 11.9 7.5 25.8 14.5 6.4 9.3 16.0 12.4 4.1 7.8 16.2 37.7 12.7 10.1 10.7 29.0 12.6 43.1 24.1 13.2 32.0 18.2 27.9 7.1 17.0 19.1 23.4 12.5 12.9 10.6 4.4 14.6 14.6 8.6 13.1 16.6 16.8 30.8 13.9 14.4 41.6 7.0 19.0 24.4 0.1 0.9 0.2 1.2 1.7 2.2 0.8 1.1 1.4 1.1 1.0 1.6 1.3 0.1 0.8 0.6 0.7 1.4 1.4 2.2 2.6 2.6 2.4 2.0 2.3 2.6 2.7 2.5 2.6 2.5 3.1 5.4 0.0 1.1 3.6 6.0 10.1 8.6 1.8 4.0 6.4 5.1 4.3 2.7 1.5 2.6 5.5 29.2 5.3 4.5 2.0 0.0 2.4 0.4 2.8 5.0 4.6 6.6 6.9 7.1 2.7 11.7 3.6 4.1 3.2 0.0 3.5 3.9 3.7 2.8 3.3 7.2 2.5 4.1 1.3 2.7 0.9 2.1 2.8 5.4 6.5 2.7 2.6 2.1 10.1 7.0 2.7 0.8 3.4 4.4 8.7 0.6 2.3 1.3 16.7 0.0 11.6 4.0 8.0 4.0 5.5 9.1 3.3 4.2 3.1 3.1 5.5 VPS33A ENSG00000139719 "VPS33A core subunit of CORVET and HOPS complexes" Q96AX1 12 122229564-122266494 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Autophagy, Protein transport, Transport" "Disease variant, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA038701 Approved Nucleoplasm NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 16: U-266 - Nucleosome" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Nucleoplasm "HPA038701: AB_10673473" "unprognostic (3.98e-2)" "unprognostic (2.90e-2)" "unprognostic (4.07e-2)" "unprognostic (4.61e-3)" "unprognostic (2.00e-1)" "unprognostic (2.14e-1)" "prognostic unfavorable (9.11e-5)" "unprognostic (2.17e-1)" "unprognostic (1.47e-1)" "unprognostic (2.40e-1)" "unprognostic (3.44e-3)" "unprognostic (1.25e-1)" "prognostic unfavorable (5.29e-4)" "unprognostic (4.63e-2)" "unprognostic (7.65e-2)" "prognostic favorable (2.41e-4)" "unprognostic (1.09e-2)" 4.9 6.8 7.1 6.0 7.5 7.0 6.0 8.4 9.3 4.4 7.0 6.8 5.7 5.1 7.6 5.0 5.9 4.1 4.8 7.3 8.2 4.5 6.0 5.3 8.1 7.3 7.1 5.9 5.4 6.1 9.2 8.5 7.8 4.9 5.5 10.5 4.5 4.9 9.0 7.0 5.9 6.5 6.7 6.9 5.6 8.1 7.6 9.6 4.3 6.1 6.8 5.4 4.2 8.9 13.2 17.1 17.3 6.9 13.3 10.2 20.0 11.9 12.9 20.4 12.7 28.2 6.4 14.6 9.8 8.0 14.2 11.1 31.6 12.6 17.5 19.9 16.9 15.1 11.5 24.8 17.0 20.6 15.6 11.4 10.4 14.5 11.5 16.8 13.5 16.0 34.3 7.3 13.3 14.7 10.1 21.2 25.2 10.8 18.5 17.2 16.0 17.5 8.7 13.6 12.6 19.0 25.0 7.4 22.7 17.8 31.6 13.8 8.8 9.2 14.5 17.4 11.0 23.1 54.2 23.4 14.5 13.1 12.8 29.6 11.5 19.0 11.3 12.6 10.3 12.0 12.7 12.2 12.1 8.9 9.0 10.5 9.4 13.6 15.2 7.6 18.6 10.9 7.1 7.5 8.4 9.3 7.3 8.2 7.3 7.1 7.8 6.7 7.6 8.9 5.7 9.6 3.9 6.8 14.0 3.2 4.0 8.1 3.4 18.1 5.4 4.8 7.3 5.7 6.8 7.3 10.4 21.7 11.3 10.1 3.9 15.0 23.0 5.9 6.5 6.6 18.0 12.2 13.8 12.6 21.4 7.0 8.2 5.2 14.5 10.2 9.7 10.2 21.2 3.3 13.9 7.7 6.1 11.5 5.3 13.1 8.1 13.4 3.6 10.3 20.7 12.1 15.5 8.5 15.3 15.0 8.8 11.3 12.6 2.5 8.5 11.3 12.6 17.7 19.7 5.4 6.2 38.8 31.4 7.0 3.0 21.6 13.4 10.0 8.2 2.9 VRK1 ENSG00000100749 "VRK serine/threonine kinase 1" Q99986 14 96797304-96954846 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" Neurodegeneration "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 50.4;testis: 37.1" "Cell type enhanced" "Detected in all" "Spermatocytes: 198.9;Spermatogonia: 110.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000660, HPA017929" Enhanced Supported Nucleoplasm,Cytosol Yes No "Cluster 15: NK-cells - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "HPA000660: AB_1080579, HPA017929: AB_1858770" "unprognostic (1.03e-1)" "unprognostic (1.17e-2)" "unprognostic (1.84e-2)" "unprognostic (2.24e-3)" "unprognostic (5.42e-2)" "unprognostic (1.19e-2)" "prognostic unfavorable (4.15e-4)" "unprognostic (4.20e-2)" "unprognostic (2.11e-2)" "unprognostic (5.47e-2)" "unprognostic (5.14e-2)" "unprognostic (1.60e-1)" "unprognostic (2.53e-2)" "unprognostic (6.70e-2)" "unprognostic (4.56e-2)" "unprognostic (3.36e-2)" "unprognostic (1.58e-1)" 5.9 5.2 5.9 12.8 7.1 50.4 11.5 6.0 7.9 5.2 4.3 10.8 6.5 6.5 6.9 8.9 9.2 4.4 5.2 5.9 5.1 4.9 5.5 4.9 27.1 5.3 5.5 6.0 3.2 5.4 3.1 7.6 5.4 5.0 12.3 4.4 4.3 5.0 4.7 7.4 7.2 6.7 4.8 11.3 6.5 37.1 5.9 35.5 5.9 4.6 27.9 7.7 5.4 7.0 52.4 27.0 78.5 30.2 9.2 14.9 44.8 42.8 34.4 67.1 65.4 36.0 54.7 139.2 22.4 24.3 39.2 56.5 75.5 54.4 90.5 73.4 36.4 90.5 18.7 39.3 10.2 168.5 49.2 8.5 9.7 50.4 32.6 12.8 47.0 104.8 76.6 79.0 56.9 65.5 137.1 76.5 47.8 39.9 59.3 124.5 134.2 48.6 32.3 59.3 53.2 28.0 34.2 36.4 30.8 36.0 39.3 66.6 24.4 27.9 22.8 47.7 37.3 37.7 53.5 124.8 44.7 74.6 34.8 42.7 12.3 26.2 21.5 15.5 29.0 31.3 24.9 26.4 15.7 32.7 27.1 27.3 6.5 45.6 15.2 21.4 34.9 19.4 5.9 7.1 6.0 7.9 5.9 5.1 5.3 5.5 5.4 4.8 5.9 7.0 15.3 3.2 4.6 6.8 30.6 16.8 13.8 23.3 6.2 12.4 9.3 11.3 11.8 12.8 16.7 14.7 8.4 34.8 24.8 6.3 11.7 13.5 21.3 21.1 8.3 12.4 3.0 76.2 42.0 19.4 48.3 11.4 14.8 10.8 28.5 20.0 7.1 3.3 19.2 10.1 36.2 10.4 20.3 11.8 14.9 11.5 5.6 12.0 12.4 19.7 14.2 6.2 27.8 12.1 19.8 10.3 2.2 9.8 25.4 6.1 3.0 11.2 37.6 9.6 19.7 14.3 15.1 198.9 110.9 14.1 13.9 15.1 26.8 9.2 18.1 10.4 WDR19 "DYF-2, FAP66, FLJ23127, IFT144, KIAA1638, NPHP13, ORF26, Oseg6, Pwdmp" ENSG00000157796 "WD repeat domain 19" Q8NEZ3 4 39182504-39285810 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Ectodermal dysplasia, Leber congenital amaurosis, Nephronophthisis, Senior-Loken syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 61.8;Inhibitory neurons: 82.5;Respiratory ciliated cells: 46.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC diff: 45.3;ASC TERT1: 47.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039616, HPA058847" Approved Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Centrosome, Cytosol" "HPA039616: AB_10796331, HPA058847: AB_2683834" "unprognostic (1.80e-1)" "unprognostic (9.32e-2)" "unprognostic (6.40e-2)" "unprognostic (5.69e-2)" "unprognostic (1.37e-1)" "unprognostic (1.26e-3)" "prognostic unfavorable (4.43e-4)" "unprognostic (1.06e-1)" "unprognostic (1.60e-1)" "unprognostic (9.63e-2)" "prognostic favorable (2.70e-4)" "prognostic unfavorable (8.58e-4)" "unprognostic (3.52e-2)" "unprognostic (2.40e-2)" "unprognostic (5.53e-2)" "unprognostic (1.82e-1)" "unprognostic (1.56e-2)" 7.5 8.0 3.1 5.3 2.5 3.7 9.2 5.3 3.8 10.5 10.8 6.8 1.9 16.0 13.3 3.9 20.3 8.4 4.2 2.3 2.5 8.8 6.3 8.8 4.7 5.3 3.6 17.9 5.4 8.1 9.1 6.2 2.9 7.7 4.2 13.0 5.7 8.4 2.3 5.5 4.7 9.1 3.5 4.6 6.2 14.0 2.7 6.9 16.7 2.4 4.9 6.2 6.8 3.6 6.1 5.2 10.3 12.1 45.3 47.0 4.7 7.5 17.2 8.1 10.6 2.8 6.5 10.4 4.1 7.8 17.2 4.0 10.9 5.4 8.6 0.5 8.5 2.2 10.3 6.1 16.1 9.6 2.6 30.5 11.1 11.9 7.2 24.6 10.7 11.0 8.7 9.1 9.9 2.1 7.7 8.1 3.5 3.7 5.6 8.2 10.4 4.2 7.0 2.9 11.5 10.4 10.2 2.4 6.1 13.1 5.5 3.6 7.9 7.9 5.3 17.5 7.8 7.2 7.6 7.6 11.9 3.3 3.7 0.1 0.3 0.2 0.3 0.5 0.3 0.8 0.5 0.6 0.3 1.2 0.5 0.6 0.3 0.8 0.5 0.1 0.3 0.2 3.1 2.5 5.3 3.8 2.3 2.5 5.3 3.6 2.9 3.5 2.7 3.6 5.5 12.8 9.3 26.1 5.4 4.8 4.9 4.6 2.2 10.1 7.3 7.4 4.5 2.8 9.4 18.4 10.4 1.2 1.8 0.7 0.0 5.5 5.1 32.3 14.6 6.7 2.4 4.0 61.8 3.6 3.2 10.8 2.0 12.0 2.5 13.4 4.2 10.0 3.2 25.2 82.5 2.0 12.2 3.2 3.6 3.4 16.4 3.0 1.8 19.7 1.8 6.7 1.0 18.1 19.7 2.9 0.2 18.8 3.9 3.0 0.3 4.0 46.6 21.7 0.0 10.9 7.9 33.8 10.2 3.9 4.7 1.4 2.9 13.1 1.1 1.9 WDR35 "FAP118, IFT121, IFTA1, KIAA1336, MGC33196" ENSG00000118965 "WD repeat domain 35" Q9P2L0 2 19910263-19990105 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 36.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "basophil: 2.9" "Lineage enriched" "Detected in single" 5 "granulocytes: 2.9" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044147 Approved NA NA "Cluster 34: Basophils - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 49: Ciliated cells - Cilium organization" "HPA044147: AB_10970242" "unprognostic (2.51e-1)" "unprognostic (4.93e-2)" "unprognostic (9.13e-2)" "unprognostic (4.01e-2)" "unprognostic (3.66e-2)" "unprognostic (2.79e-1)" "unprognostic (2.94e-3)" "unprognostic (3.08e-2)" "unprognostic (3.23e-1)" "unprognostic (2.91e-1)" "unprognostic (3.01e-2)" "unprognostic (3.68e-2)" "unprognostic (6.98e-2)" "unprognostic (2.17e-2)" "unprognostic (5.03e-2)" "unprognostic (1.02e-1)" "unprognostic (2.71e-1)" 3.6 5.1 4.3 2.7 4.4 2.0 7.8 4.1 4.7 6.6 10.0 4.9 1.7 9.3 7.2 2.9 11.3 3.5 3.3 4.1 5.5 7.9 2.0 4.5 2.7 5.5 5.5 9.6 3.8 14.4 9.0 2.7 5.1 5.5 3.0 12.6 3.0 6.3 2.5 3.4 3.0 6.2 4.9 2.0 3.7 10.6 6.0 4.8 8.8 2.6 2.6 4.4 3.7 5.7 8.3 10.4 9.9 9.5 7.6 7.4 0.5 4.2 7.4 6.0 4.3 3.2 3.6 0.0 1.8 4.7 5.0 2.6 10.6 10.3 9.9 1.6 8.2 8.1 6.6 10.0 6.6 15.8 3.1 9.0 7.2 10.7 15.2 10.8 7.4 3.3 13.1 2.3 6.1 3.0 2.3 11.4 11.9 1.5 10.0 0.0 7.1 3.5 12.8 4.7 18.6 21.9 6.9 4.6 12.3 4.7 4.9 3.4 7.7 6.8 3.3 9.4 12.4 4.7 8.3 0.0 12.7 1.1 6.8 2.9 0.1 0.3 0.5 0.0 0.1 0.4 0.3 0.3 0.2 0.6 0.3 0.4 0.2 0.4 0.0 0.1 0.4 0.2 4.3 4.4 4.1 4.7 4.1 5.5 5.5 5.5 5.1 4.9 6.0 5.7 2.9 3.2 9.0 36.6 5.7 3.3 3.5 5.0 2.2 6.5 5.8 7.2 10.8 11.5 7.2 11.0 2.1 0.2 2.9 0.3 0.0 3.3 1.9 16.1 13.1 3.1 6.0 7.8 30.0 4.0 1.0 9.7 5.1 4.0 9.5 9.4 3.6 2.4 1.3 6.7 21.9 1.5 4.1 0.9 2.8 3.5 10.2 2.0 3.6 18.7 1.1 10.0 2.1 25.1 27.6 6.3 0.7 10.9 2.4 2.0 0.7 5.6 28.6 15.2 6.6 14.6 7.4 28.8 9.0 2.2 2.6 0.3 5.4 9.0 1.5 1.1 XKR9 ENSG00000221947 "XK related 9" Q5GH70 8 70669339-70790371 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 5.3;testis: 7.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 42.0;Inhibitory neurons: 17.9;Oligodendrocytes: 23.0;Spermatocytes: 82.3;Spermatogonia: 19.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 3.3;hTCEpi: 6.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA044430 Enhanced Approved Mitochondria NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 45: Intestine - Brush border" "Cluster 30: Epithelial cell lines - Translation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Mitochondria "HPA044430: AB_10961283" "unprognostic (1.79e-2)" "unprognostic (7.31e-2)" "unprognostic (1.42e-1)" "unprognostic (1.40e-3)" "unprognostic (1.85e-1)" "unprognostic (1.22e-1)" "unprognostic (2.23e-2)" "unprognostic (9.33e-2)" "unprognostic (1.63e-1)" "unprognostic (2.63e-2)" "prognostic unfavorable (7.20e-4)" "unprognostic (2.29e-1)" "unprognostic (6.96e-6)" "unprognostic (3.65e-1)" "unprognostic (3.26e-1)" "unprognostic (4.04e-3)" "unprognostic (3.71e-2)" 0.2 1.1 0.5 0.4 0.5 0.5 0.4 0.0 1.6 0.2 0.0 0.9 2.6 0.2 1.3 0.5 0.1 2.2 0.2 0.5 0.3 0.5 3.3 0.6 0.5 0.6 0.2 0.2 0.3 0.1 0.6 0.4 1.1 0.6 0.5 2.4 0.5 0.0 0.2 0.9 5.3 0.3 0.0 0.5 1.8 7.7 0.3 0.5 0.4 0.3 0.5 1.0 0.2 1.5 2.3 0.1 0.5 0.2 0.0 0.5 0.3 0.9 0.4 0.3 0.9 3.3 0.2 0.3 1.5 0.0 1.1 0.1 0.0 0.5 1.1 0.4 0.3 0.2 0.2 0.2 0.0 0.7 1.2 0.6 6.4 0.1 0.0 0.2 0.0 1.6 0.1 2.3 0.1 0.3 0.4 0.3 1.3 0.1 0.4 0.3 0.6 0.1 0.1 1.7 1.4 0.2 0.4 1.0 0.3 0.1 0.3 0.1 0.2 0.3 0.6 0.4 0.3 2.0 0.5 1.5 0.1 0.2 0.2 0.2 0.0 0.0 0.2 0.0 0.4 0.2 0.4 0.2 0.0 0.2 0.6 0.4 0.1 0.2 0.0 0.0 0.8 0.0 0.5 0.5 0.0 1.6 0.5 0.3 0.6 0.2 1.1 0.0 0.3 1.5 0.1 6.4 2.2 14.4 1.1 2.7 3.5 3.9 4.6 2.2 0.7 1.0 0.4 1.5 3.3 0.0 8.4 1.0 0.3 1.4 0.0 1.6 5.3 0.5 0.3 0.6 0.0 0.0 42.0 4.6 0.6 0.8 6.1 0.6 0.0 0.3 0.0 2.3 0.3 1.7 17.9 3.4 0.0 0.3 0.4 4.9 0.9 0.2 0.0 1.9 0.0 1.5 2.1 1.5 23.0 6.0 1.3 0.4 0.8 1.7 11.7 0.5 3.2 5.3 0.0 0.1 0.2 82.3 19.7 0.5 0.9 1.0 1.0 0.1 0.4 2.3 XPO5 KIAA1291 ENSG00000124571 "Exportin 5" Q9HAV4 6 43522334-43576038 "Predicted intracellular proteins, Transporters" "Host-virus interaction, Protein transport, RNA-mediated gene silencing, Transport" "RNA-binding, tRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012357, HPA018402, HPA023959, HPA029909" Enhanced Enhanced Nucleoplasm NA NA 13000 "Cluster 27: Non-specific - Gene expression" "Cluster 23: Testis - Cell cycle regulation" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "CAB012357: , HPA018402: AB_1848330, HPA023959: AB_1848331, HPA029909: AB_10611245" "unprognostic (6.98e-2)" "unprognostic (4.34e-2)" "unprognostic (5.13e-2)" "prognostic unfavorable (4.94e-7)" "unprognostic (6.16e-2)" "unprognostic (2.43e-2)" "prognostic unfavorable (3.98e-8)" "unprognostic (4.78e-1)" "unprognostic (4.72e-3)" "unprognostic (1.72e-1)" "unprognostic (4.86e-2)" "unprognostic (1.49e-1)" "unprognostic (1.07e-2)" "unprognostic (1.97e-1)" "unprognostic (1.45e-1)" "unprognostic (9.48e-2)" "unprognostic (5.66e-3)" 7.3 8.0 4.6 9.1 5.3 8.3 8.5 5.1 5.8 7.6 4.1 7.2 6.3 8.0 9.1 12.0 6.9 5.8 7.0 4.7 4.7 7.4 6.7 6.5 8.7 4.8 4.6 6.3 14.0 11.1 6.5 7.6 4.5 7.9 8.8 11.7 8.1 7.1 11.2 12.3 6.4 9.7 4.2 6.9 8.3 23.7 5.2 12.0 13.1 6.0 11.2 11.2 7.9 4.7 48.8 28.5 46.7 94.4 23.7 19.9 43.3 24.8 17.3 47.9 34.4 79.1 16.5 65.6 31.4 23.7 45.1 40.8 78.4 36.2 53.5 48.0 61.9 63.6 34.5 57.8 34.0 71.0 32.6 14.5 36.8 50.4 78.0 17.2 34.6 46.0 138.5 50.2 32.6 59.5 53.9 35.1 50.1 132.3 28.7 57.9 49.5 49.2 27.6 37.6 95.7 39.7 34.5 31.5 44.7 40.6 36.3 56.1 29.2 35.2 41.9 34.0 52.8 31.8 37.1 126.3 12.6 60.7 38.4 0.0 4.3 3.1 4.8 5.4 4.4 2.8 4.3 5.3 4.9 2.4 3.4 4.6 0.4 7.1 10.8 1.4 4.7 4.0 4.6 5.3 5.1 5.8 4.7 4.7 4.8 4.6 4.5 4.2 5.2 4.7 4.7 6.4 3.3 21.2 6.0 8.9 6.8 4.6 5.2 11.3 7.0 7.4 6.5 2.8 3.5 11.0 8.4 5.5 8.4 3.6 1.9 6.7 12.3 7.1 10.9 6.6 14.4 9.4 31.7 7.7 6.5 7.5 10.2 7.5 11.4 13.4 2.5 4.6 6.2 21.9 35.2 5.9 2.0 5.3 2.5 13.5 4.1 4.9 1.8 25.3 5.1 4.5 13.4 26.7 32.0 6.6 2.2 8.2 10.8 13.0 4.1 4.7 5.5 14.3 0.0 10.0 7.3 26.9 23.5 10.2 7.1 4.4 5.4 11.5 7.2 5.8 XRCC6 "D22S671, D22S731, G22P1, KU70, ML8" ENSG00000196419 "X-ray repair cross complementing 6" P12956 22 41621163-41664048 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Host-virus interaction, Immunity, Innate immunity, Transcription, Transcription regulation" "Activator, DNA-binding, Helicase, Hydrolase, Lyase, Multifunctional enzyme" "Cancer-related genes, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 579.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004254, HPA047549, HPA062226" Enhanced Enhanced Nucleoplasm No No 700000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 23: Testis - Cell cycle regulation" "Cluster 21: OE19 - Mitochondria" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "CAB004254: AB_628453, HPA047549: AB_2680085, HPA062226: AB_2684716" "unprognostic (5.55e-2)" "unprognostic (2.39e-2)" "unprognostic (1.82e-3)" "unprognostic (2.39e-1)" "unprognostic (2.47e-2)" "unprognostic (9.17e-2)" "unprognostic (1.16e-3)" "unprognostic (2.32e-2)" "unprognostic (2.21e-1)" "unprognostic (2.11e-1)" "unprognostic (1.89e-2)" "unprognostic (1.33e-1)" "unprognostic (2.06e-3)" "unprognostic (1.22e-1)" "unprognostic (2.28e-1)" "unprognostic (4.77e-2)" "unprognostic (7.95e-2)" 143.7 183.4 84.9 153.4 89.3 218.2 143.3 87.8 100.8 152.1 87.2 159.5 136.8 153.8 111.3 192.1 151.4 105.5 176.1 89.2 94.7 136.9 142.4 133.2 196.6 89.5 86.8 169.8 119.0 156.5 122.6 155.0 92.2 132.7 164.9 115.6 130.8 144.4 273.0 168.3 142.8 161.0 93.5 143.1 138.6 231.2 87.9 224.1 137.8 184.3 222.2 162.6 142.0 96.4 554.6 388.0 527.9 455.5 313.5 279.5 413.8 394.7 464.6 794.9 656.4 570.4 335.7 886.2 319.8 478.1 357.4 400.6 739.2 486.8 803.2 493.4 921.2 478.8 435.2 559.5 281.5 1142.2 520.5 252.7 323.1 501.2 275.0 319.8 505.6 371.6 470.2 360.1 523.1 589.9 589.0 390.6 482.1 1138.4 452.1 660.0 562.3 695.6 440.4 404.4 243.3 174.6 644.1 328.2 455.7 392.9 382.2 439.0 366.2 394.3 546.2 354.0 522.4 354.0 671.9 896.1 369.4 441.3 476.4 146.0 264.3 227.6 243.6 296.5 258.4 256.5 269.5 269.2 324.1 246.9 293.2 262.5 69.2 253.2 307.0 191.7 325.9 600.8 84.9 89.3 87.8 100.8 89.2 94.7 89.5 86.8 92.2 93.5 87.9 96.4 96.6 96.1 142.5 18.6 132.6 124.0 201.0 219.0 83.1 107.1 80.1 83.4 89.4 115.8 160.4 82.8 62.6 422.3 104.9 97.3 166.3 205.4 119.6 86.1 87.0 117.0 98.6 125.4 24.5 182.7 317.2 123.9 73.4 105.9 119.7 156.4 70.3 103.7 170.2 87.5 29.5 114.7 166.8 98.1 116.7 62.9 126.8 110.4 88.9 17.8 182.8 149.7 89.6 26.2 30.5 150.9 106.6 126.7 116.0 112.0 113.7 140.3 112.6 103.6 164.3 102.4 127.4 579.8 314.4 91.5 102.1 362.2 136.9 150.6 166.8 137.5 YTHDC2 "DKFZp564A186, FLJ10053, FLJ2194" ENSG00000047188 "YTH domain containing 2" Q9H6S0 5 113513694-113595285 "Enzymes, Predicted intracellular proteins" "Differentiation, Meiosis, Oogenesis, Spermatogenesis" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 129.8;Inhibitory neurons: 146.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037364, HPA072678" Approved Approved "Nucleoplasm,Nuclear bodies,Cytoplasmic bodies" NA NA "Cluster 37: B-cells - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "Nuclear bodies, Cytoplasmic bodies" "HPA037364: AB_10672788, HPA072678: AB_2686548" "unprognostic (2.09e-1)" "unprognostic (2.10e-1)" "prognostic favorable (1.82e-5)" "unprognostic (4.33e-3)" "unprognostic (1.45e-1)" "unprognostic (6.48e-3)" "unprognostic (1.96e-1)" "unprognostic (7.82e-3)" "unprognostic (3.55e-2)" "unprognostic (8.56e-3)" "unprognostic (4.61e-2)" "unprognostic (2.03e-1)" "unprognostic (4.15e-2)" "unprognostic (3.05e-1)" "unprognostic (9.96e-2)" "unprognostic (1.08e-2)" "unprognostic (2.56e-2)" 8.4 9.7 5.2 11.3 5.8 9.9 10.1 8.8 6.6 8.9 7.8 8.7 9.3 9.2 8.6 9.4 8.3 8.0 7.6 6.1 5.1 8.5 12.6 7.4 13.8 5.3 5.8 11.0 8.7 15.5 8.7 6.9 5.3 8.1 10.0 18.3 8.9 7.4 11.5 11.3 10.1 7.9 5.1 11.4 9.2 14.8 4.7 10.2 9.2 10.9 12.9 9.8 8.9 7.1 16.0 14.2 18.1 30.7 9.8 12.9 19.7 12.1 13.4 15.2 23.6 10.0 8.8 29.1 8.5 10.2 19.5 15.3 22.0 27.2 19.8 12.6 19.9 15.8 25.8 13.6 14.5 12.8 13.4 10.6 10.3 9.6 17.4 14.3 21.5 13.0 15.8 13.0 13.6 5.3 17.8 9.1 8.4 4.7 9.2 7.4 15.6 22.7 12.7 20.9 14.4 12.0 16.3 11.7 12.7 11.3 16.6 11.4 18.8 23.2 8.1 12.1 16.7 13.3 18.0 18.0 13.3 14.4 10.1 0.0 2.8 2.9 2.8 1.9 3.3 7.3 3.2 3.0 2.4 5.1 3.4 2.9 1.0 4.3 3.3 3.6 2.6 1.2 5.2 5.8 8.8 6.6 6.1 5.1 5.3 5.8 5.3 5.1 4.7 7.1 27.4 28.9 32.8 61.0 39.6 13.3 21.8 14.7 15.9 59.9 17.6 17.7 17.7 14.3 25.3 12.9 83.4 13.7 34.0 12.3 0.0 17.8 47.5 15.5 24.5 24.0 7.2 16.6 129.8 18.6 8.3 22.4 34.1 17.2 12.6 69.0 20.0 25.7 17.3 52.2 146.3 14.2 20.3 30.0 13.2 44.2 19.9 26.8 12.4 95.5 23.9 21.4 16.5 94.5 97.6 18.0 7.8 14.7 20.0 14.4 16.0 17.8 24.9 88.9 26.3 34.0 26.6 93.8 37.8 19.2 14.3 18.1 33.0 33.4 16.7 18.5 ZGRF1 "C4orf21, FLJ11331" ENSG00000138658 "Zinc finger GRF-type containing 1" Q86YA3 4 112539333-112636995 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 7.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 18.0;Microglial cells: 17.8;Oligodendrocytes: 27.5;Spermatocytes: 22.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA030704, HPA030706" Uncertain Approved Cytosol NA Yes "Cluster 7: Monocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA030704: AB_2673577, HPA030706: AB_10601784" "unprognostic (8.48e-2)" "unprognostic (6.17e-2)" "unprognostic (9.51e-2)" "unprognostic (1.53e-1)" "unprognostic (1.10e-1)" "unprognostic (1.84e-3)" "unprognostic (5.83e-3)" "unprognostic (1.45e-1)" "unprognostic (5.89e-4)" "unprognostic (4.74e-2)" "unprognostic (4.30e-2)" "unprognostic (3.72e-3)" "unprognostic (7.60e-10)" "unprognostic (3.45e-2)" "unprognostic (2.93e-1)" "unprognostic (1.15e-1)" "unprognostic (2.02e-4)" 1.0 0.7 0.9 2.0 1.4 7.8 1.3 2.2 1.5 0.9 0.1 1.1 1.2 1.2 0.3 1.0 0.8 0.5 0.7 0.8 0.7 0.5 0.6 0.9 2.5 1.3 0.9 1.1 0.7 0.3 1.3 1.7 1.3 0.9 1.4 4.3 0.9 0.4 1.2 1.4 1.5 0.9 1.0 1.8 0.9 3.6 1.0 5.2 0.8 0.6 2.9 0.7 0.8 2.1 5.0 3.6 12.1 8.6 0.9 1.6 4.7 8.8 3.7 8.7 7.8 6.9 7.3 13.2 2.5 2.7 3.6 4.0 12.7 4.7 10.0 7.3 3.1 8.3 5.8 2.1 0.4 18.5 5.3 0.8 0.6 11.0 3.0 1.2 3.5 13.6 12.0 14.3 6.0 8.2 25.0 6.7 6.3 5.2 4.2 13.8 18.1 4.5 1.5 4.4 5.6 9.5 3.9 5.3 1.7 8.8 2.5 5.4 4.2 10.9 10.6 5.9 7.1 5.5 10.1 17.0 4.9 6.3 6.3 0.0 0.1 0.3 0.2 0.7 0.1 0.3 0.1 0.0 0.0 0.5 0.4 0.4 0.2 0.2 0.1 0.7 0.2 0.1 0.9 1.4 2.2 1.5 0.8 0.7 1.3 0.9 1.3 1.0 1.0 2.1 3.3 0.0 1.3 10.4 5.4 0.0 1.3 0.0 0.6 10.4 2.1 1.7 2.4 0.0 3.7 1.8 8.4 3.5 10.4 2.1 0.0 1.0 2.9 1.8 3.5 1.9 1.2 11.1 18.0 0.5 2.7 2.3 4.6 2.8 2.5 12.2 1.1 0.6 1.8 5.0 14.5 1.8 0.0 1.6 0.0 2.8 0.6 4.1 0.0 17.8 1.3 1.6 6.2 17.6 27.5 0.6 1.4 2.2 10.5 0.8 0.7 0.3 0.7 17.6 0.0 3.1 2.7 22.1 15.6 3.6 0.0 0.8 5.0 2.2 2.5 0.9 ZNF608 "DKFZp434M098, KIAA1281, NY-REN-36" ENSG00000168916 "Zinc finger protein 608" Q9ULD9 5 124636913-124748807 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Astrocytes: 105.4;Inhibitory neurons: 141.2;Oligodendrocyte precursor cells: 219.2;Oligodendrocytes: 209.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.5;naive B-cell: 1.6" "Group enriched" "Detected in many" 4 "B-cells: 1.6;granulocytes: 2.5" "Cell line enhanced" "Detected in many" "AF22: 61.0;AN3-CA: 39.2;REH: 110.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005545, HPA076984" Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 10: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm Mitochondria "HPA005545: AB_1080742, HPA076984: " "unprognostic (3.82e-2)" "unprognostic (2.50e-2)" "unprognostic (1.92e-1)" "prognostic unfavorable (5.47e-4)" "unprognostic (3.75e-1)" "unprognostic (2.26e-1)" "unprognostic (3.04e-2)" "unprognostic (5.02e-2)" "unprognostic (7.52e-2)" "unprognostic (5.24e-2)" "unprognostic (3.67e-1)" "unprognostic (2.69e-2)" "prognostic unfavorable (1.28e-5)" "unprognostic (6.36e-2)" "unprognostic (2.80e-1)" "unprognostic (3.02e-1)" "unprognostic (9.56e-2)" 6.1 9.9 10.4 4.2 14.0 1.4 6.7 12.1 10.4 7.4 4.1 5.6 11.1 4.8 2.7 3.5 9.1 6.9 9.0 11.7 12.8 5.3 2.7 10.7 8.0 14.7 12.4 6.3 8.4 3.7 4.4 3.1 12.4 5.6 7.2 23.6 5.7 4.5 6.4 3.3 6.6 4.2 9.2 2.8 6.7 9.4 12.4 4.8 9.2 3.2 8.0 3.1 4.4 17.1 0.2 1.1 61.0 39.2 8.9 14.5 0.0 0.0 1.6 0.3 3.6 6.6 18.6 20.8 20.2 0.0 9.8 0.8 4.2 3.9 0.3 0.0 9.9 0.0 0.1 0.3 13.7 0.0 1.9 14.6 11.0 1.9 1.7 9.1 13.2 0.1 2.0 0.4 3.3 0.1 0.0 0.0 25.9 0.5 0.8 110.6 5.4 0.1 8.7 0.9 9.2 32.0 0.0 0.7 14.1 34.5 3.5 1.8 3.5 12.3 22.9 0.3 3.9 9.7 10.2 36.9 3.1 0.6 17.7 2.5 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.6 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 10.4 14.0 12.1 10.4 11.7 12.8 14.7 12.4 12.4 9.2 12.4 17.1 25.2 32.1 35.3 105.4 7.4 1.3 10.4 5.5 31.3 35.8 8.6 7.7 20.1 18.6 36.2 14.7 39.6 0.8 1.5 13.0 3.9 16.7 16.9 30.6 3.0 23.4 40.0 1.3 17.0 8.7 3.8 9.9 11.7 16.8 0.0 7.3 11.4 2.0 0.8 42.1 141.2 6.1 4.1 0.3 2.2 8.8 2.1 1.3 7.2 28.1 2.1 31.2 0.0 219.2 209.9 6.2 7.3 1.5 3.7 3.5 8.1 8.4 13.2 36.7 0.0 13.2 7.7 19.2 7.2 11.8 0.9 0.4 1.5 19.1 9.8 2.5 ZNF624 KIAA1349 ENSG00000197566 "Zinc finger protein 624" Q9P2J8 17 16620734-16653856 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 16.6;Oligodendrocytes: 21.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SuSa: 12.1" "Low region specificity" "Detected in all" "HPA023157, HPA023244" Uncertain Approved Vesicles NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 23: Spermatids - Flagellum & Golgi organization" Vesicles "HPA023157: AB_2671094, HPA023244: AB_2671117" "unprognostic (2.47e-1)" "unprognostic (8.75e-2)" "unprognostic (3.51e-2)" "unprognostic (3.97e-3)" "unprognostic (1.64e-1)" "unprognostic (3.77e-2)" "unprognostic (1.24e-1)" "unprognostic (2.18e-1)" "unprognostic (1.10e-2)" "unprognostic (4.76e-2)" "unprognostic (1.40e-1)" "unprognostic (1.62e-1)" "unprognostic (1.75e-2)" "unprognostic (1.52e-1)" "unprognostic (7.88e-2)" "unprognostic (1.09e-1)" "unprognostic (2.97e-1)" 1.6 0.7 1.3 1.5 2.2 1.1 1.8 1.4 2.5 2.3 0.3 1.7 1.3 2.5 1.2 1.3 2.0 1.2 1.5 1.2 1.8 1.8 0.8 2.0 2.4 2.5 1.9 3.6 0.8 2.5 0.4 3.0 2.1 1.0 1.8 2.6 0.9 1.5 0.4 1.5 1.4 2.0 1.8 3.5 1.9 4.8 2.5 3.1 2.3 0.9 2.1 1.4 0.9 4.1 1.1 1.8 5.3 1.8 2.6 3.1 1.4 1.8 3.1 3.4 3.1 0.9 1.0 2.7 1.5 2.4 1.1 1.5 1.5 1.9 3.7 2.9 1.8 3.0 0.9 0.8 2.5 2.1 2.9 3.5 4.4 1.9 3.8 1.8 3.1 3.4 1.9 0.7 4.5 1.6 5.2 0.8 0.9 3.8 0.8 5.5 9.0 0.8 2.3 2.2 1.6 3.2 2.0 1.5 2.1 12.1 1.2 0.9 4.4 3.2 1.2 1.2 1.3 1.2 0.9 0.0 1.5 0.0 2.7 1.0 1.0 2.0 1.7 3.3 2.5 1.6 2.0 2.0 1.9 2.9 2.2 1.3 0.2 2.8 1.5 0.5 1.5 1.1 1.3 2.2 1.4 2.5 1.2 1.8 2.5 1.9 2.1 1.8 2.5 4.1 4.2 0.0 0.0 5.9 2.9 0.5 0.4 1.1 0.6 5.1 1.4 1.0 2.6 1.5 2.2 0.0 2.1 1.3 2.4 1.9 3.9 1.3 11.2 1.3 4.1 3.0 0.0 1.7 5.6 1.0 1.5 2.7 1.5 1.4 3.8 4.1 4.6 0.3 2.6 8.4 9.6 1.3 0.0 4.6 1.6 2.1 1.5 2.3 0.0 8.4 1.2 2.8 2.1 16.6 21.1 1.5 0.8 2.6 0.6 0.5 0.8 2.0 3.6 3.2 0.0 2.4 4.1 12.0 8.4 0.9 0.9 1.5 2.3 4.6 0.9 1.1 ZNF99 "C19orf9, MGC24986" ENSG00000213973 "Zinc finger protein 99" A8MXY4 19 22752183-22784151 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 4 "testis: 1.6" "Cell type enhanced" "Detected in some" "Oligodendrocyte precursor cells: 5.0;Sertoli cells: 19.7;Spermatocytes: 19.5;Spermatogonia: 8.5" "Cancer enriched" "Detected in single" 9 "testis cancer: 1.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "unprognostic (8.31e-2)" "unprognostic (2.77e-1)" "unprognostic (4.19e-2)" "unprognostic (4.78e-2)" "unprognostic (1.96e-2)" "unprognostic (2.28e-1)" "unprognostic (9.83e-2)" "unprognostic (4.22e-2)" "unprognostic (2.65e-1)" "unprognostic (1.92e-3)" "unprognostic (2.61e-1)" "unprognostic (8.92e-2)" "unprognostic (1.35e-1)" "unprognostic (1.39e-2)" "unprognostic (3.49e-1)" "unprognostic (4.05e-3)" "unprognostic (8.55e-2)" 0.1 0.0 0.2 0.0 0.1 0.1 0.2 0.2 0.3 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 1.6 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.5 0.1 0.1 0.2 0.0 0.0 0.2 0.1 0.2 0.3 0.2 0.1 0.2 0.2 0.2 0.0 0.1 0.3 0.4 0.0 0.0 2.0 0.0 0.0 0.1 0.0 0.0 0.9 0.4 0.4 1.6 0.0 0.0 0.0 0.0 0.8 0.0 0.0 1.9 0.0 1.1 0.1 1.1 0.4 0.0 0.0 1.2 0.0 0.3 0.7 0.0 0.0 0.0 4.0 0.7 0.2 0.2 0.0 0.4 0.0 0.0 0.0 0.0 1.2 0.3 0.0 0.0 0.0 0.0 0.2 0.0 5.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 19.7 0.4 0.6 19.5 8.5 0.0 0.0 0.3 0.1 0.4 0.0 0.2