Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" A3GALT2 "A3GALT2P, IGB3S, IGBS3S" ENSG00000184389 "Alpha 1,3-galactosyltransferase 2" U3KPV4 1 33306766-33321098 "Enzymes, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HeLa: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 20: HeLa - Mitochondria" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (1.86e-2)" "unprognostic (2.36e-2)" "unprognostic (2.39e-1)" "unprognostic (1.18e-1)" "unprognostic (2.61e-3)" "unprognostic (4.96e-2)" "unprognostic (6.83e-2)" "unprognostic (5.81e-2)" "unprognostic (1.23e-1)" "unprognostic (1.89e-1)" "unprognostic (4.90e-8)" "unprognostic (1.17e-1)" "unprognostic (1.12e-2)" "unprognostic (7.87e-2)" 0.1 0.0 0.1 0.1 0.0 0.2 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.0 0.1 0.1 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AAAS ENSG00000094914 "Aladin WD repeat nucleoporin" Q9NRG9 12 53307456-53324864 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040086 Approved Approved "Nuclear membrane,Centrosome,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 71: Testis - DNA repair" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nuclear membrane" "Centrosome, Cytosol" "HPA040086: AB_10805602" "unprognostic (1.53e-1)" "unprognostic (1.24e-1)" "unprognostic (1.83e-1)" "unprognostic (1.81e-2)" "unprognostic (1.76e-1)" "unprognostic (2.64e-1)" "unprognostic (1.51e-3)" "unprognostic (1.70e-1)" "unprognostic (4.34e-1)" "unprognostic (1.00e-2)" "unprognostic (1.57e-2)" "unprognostic (6.64e-2)" "prognostic unfavorable (2.93e-4)" "unprognostic (1.95e-1)" "unprognostic (9.82e-2)" "unprognostic (2.53e-1)" "unprognostic (7.44e-2)" 17.0 36.3 12.3 13.8 15.0 19.1 17.1 15.2 15.6 20.3 15.1 19.1 12.3 19.1 7.2 19.3 19.9 9.4 22.7 12.9 13.7 21.7 24.6 14.0 17.6 14.3 14.1 19.2 23.9 18.0 24.8 17.4 14.8 18.4 15.1 12.3 18.5 11.7 22.6 17.3 17.7 16.8 13.7 22.2 21.6 27.3 14.0 25.2 19.4 18.5 21.6 17.8 17.9 17.2 26.1 77.3 63.2 38.0 28.6 32.2 38.9 29.8 31.3 72.6 42.1 54.0 56.7 62.2 47.4 37.3 41.9 37.6 106.4 78.8 42.1 41.0 68.1 49.7 29.9 40.7 26.4 45.5 37.9 28.1 39.4 48.9 44.6 40.4 56.6 56.2 67.6 70.6 30.4 72.8 71.2 46.1 40.0 27.7 53.1 72.1 39.3 69.4 38.2 17.5 32.8 41.3 20.2 46.9 21.0 40.2 61.2 38.8 25.5 34.9 51.1 27.4 32.9 32.5 43.5 54.7 25.6 39.6 40.5 1.0 17.7 10.7 18.4 20.2 20.8 20.0 15.9 16.8 18.8 21.8 21.7 21.4 1.1 10.5 22.5 22.6 17.4 15.2 12.3 15.0 15.2 15.6 12.9 13.7 14.3 14.1 14.8 13.7 14.0 17.2 11.7 12.8 7.8 17.9 15.1 7.4 19.0 26.2 10.2 11.8 13.2 13.0 8.2 17.2 15.4 14.7 16.7 58.4 13.7 9.3 13.7 20.4 12.5 11.9 12.9 11.7 8.4 41.2 7.3 18.3 49.5 14.9 13.3 8.9 8.2 13.1 11.0 12.0 28.5 1.7 6.6 13.1 18.3 12.4 9.3 26.2 17.7 10.6 10.6 5.6 11.6 18.0 15.5 6.6 11.4 8.9 11.0 12.8 20.8 8.1 11.2 18.5 12.6 15.5 19.7 11.0 39.7 34.2 40.5 13.1 7.4 36.5 11.4 14.9 17.2 13.0 ABCA4 "ABCR, ARMD2, CORD3, FFM, RP19, STGD, STGD1" ENSG00000198691 "ATP binding cassette subfamily A member 4" P78363 1 93992834-94121148 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Sensory transduction, Transport, Vision" Translocase "Age-related macular degeneration, Cone-rod dystrophy, Disease variant, Retinitis pigmentosa, Stargardt disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 32 "choroid plexus: 144.6;retina: 461.0" "Group enriched" "Detected in some" 12 "Cone photoreceptor cells: 450.4;Rod photoreceptor cells: 482.9" "Cancer enhanced" "Detected in many" "lung cancer: 3.1" "Region enriched" "Detected in some" 6 "hippocampal formation: 9.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 3.1;EFO-21: 6.8;HeLa: 2.3;SK-BR-3: 3.0;SuSa: 3.1" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA064420, HPA078826" Enhanced Approved Cytosol NA NA "Cluster 79: Retina - Phototransduction" "Cluster 38: EFO-21 - Unknown function" "Cluster 46: Photoreceptor cells - Phototransduction" Cytosol "HPA064420: , HPA078826: " "unprognostic (1.25e-1)" "unprognostic (3.93e-1)" "unprognostic (3.29e-2)" "unprognostic (7.17e-4)" "unprognostic (1.28e-1)" "unprognostic (3.00e-1)" "unprognostic (1.38e-2)" "prognostic favorable (2.45e-4)" "unprognostic (3.77e-2)" "unprognostic (5.25e-1)" "unprognostic (3.70e-1)" "unprognostic (5.18e-2)" "unprognostic (1.17e-9)" "unprognostic (1.61e-2)" "unprognostic (1.55e-1)" "unprognostic (2.47e-1)" "prognostic unfavorable (2.72e-4)" 0.5 0.0 0.4 0.1 0.3 0.0 0.8 1.1 0.7 0.5 144.6 0.2 2.5 0.1 8.4 0.2 0.4 0.1 0.2 9.3 0.1 8.7 0.9 0.3 0.4 0.4 0.5 0.2 0.0 0.0 0.1 0.6 0.2 0.2 0.1 461.0 0.0 1.4 0.1 2.1 2.9 0.0 0.1 0.1 0.1 1.0 1.4 0.3 0.4 0.0 0.1 0.2 0.1 0.4 0.3 0.0 0.1 0.0 0.0 0.0 3.1 0.1 0.2 0.0 0.1 0.1 0.0 0.0 6.8 0.3 0.1 0.7 0.0 0.0 0.1 0.0 0.0 0.4 2.3 0.7 0.4 0.0 0.0 0.3 0.0 0.3 0.0 0.1 0.6 0.0 0.0 0.1 0.0 0.9 0.5 0.0 1.2 0.0 0.1 0.1 0.2 0.2 0.3 0.3 0.0 0.0 0.6 3.0 0.1 3.1 0.3 0.0 0.1 0.2 1.3 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 1.1 0.7 9.3 0.1 0.4 0.5 0.2 0.1 1.4 0.4 1.2 0.0 1.1 1.3 0.0 0.1 0.2 1.7 0.0 27.9 0.5 1.3 1.1 0.0 1.8 7.3 450.4 0.3 0.0 0.0 0.0 0.0 8.8 0.3 0.1 3.1 0.0 0.0 0.4 0.0 1.5 0.2 0.0 0.9 0.0 0.2 1.4 0.3 0.1 10.1 0.6 16.2 0.0 0.3 0.0 21.9 0.0 0.0 0.0 19.7 0.0 37.3 0.0 0.5 0.0 0.0 0.0 0.4 0.0 2.6 1.3 0.4 2.3 482.9 0.0 0.1 0.4 0.0 0.2 0.0 0.0 0.3 0.0 0.3 0.6 0.7 ABCC11 MRP8 ENSG00000121270 "ATP binding cassette subfamily C member 11" Q96J66 16 48165773-48247568 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "breast: 46.4" "Cell type enhanced" "Detected in some" "Astrocytes: 3.3;Breast glandular cells: 4.4;Early spermatids: 3.3;Hepatocytes: 2.5;Late spermatids: 1.9;Spermatocytes: 4.0" "Cancer enriched" "Detected in some" 4 "breast cancer: 8.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "T-47d: 67.1" "Not detected" "Not detected" NA NA "Cluster 37: B-cells - Transcription" "Cluster 5: Breast - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (1.35e-1)" "unprognostic (3.47e-2)" "unprognostic (3.87e-2)" "unprognostic (2.47e-1)" "unprognostic (1.57e-1)" "unprognostic (6.03e-2)" "unprognostic (3.87e-2)" "unprognostic (1.56e-2)" "unprognostic (8.11e-2)" "unprognostic (2.39e-1)" "unprognostic (2.64e-1)" "unprognostic (7.05e-2)" "unprognostic (1.14e-1)" "unprognostic (2.21e-2)" "unprognostic (1.58e-1)" "unprognostic (1.13e-2)" "unprognostic (5.54e-4)" 0.1 0.0 0.2 0.0 0.3 0.1 46.4 0.4 0.3 0.0 0.2 0.0 0.3 0.1 0.0 0.0 0.5 0.1 0.0 0.2 0.2 0.0 1.6 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.2 3.6 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 2.4 0.3 0.0 0.3 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.4 0.6 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 16.0 0.1 0.0 67.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.4 0.3 0.2 0.2 0.2 0.2 0.2 0.1 0.3 0.3 0.1 0.0 0.5 3.3 0.2 0.0 0.0 0.0 0.0 0.4 4.4 0.9 0.6 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 3.3 0.3 0.1 0.1 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.0 2.5 0.0 0.0 0.6 0.0 0.0 0.3 0.0 1.9 0.0 0.2 0.0 0.0 0.0 0.5 0.0 1.0 1.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.2 0.0 4.0 0.4 0.5 0.0 0.3 0.2 0.1 0.0 0.1 ABCF3 EST201864 ENSG00000161204 "ATP binding cassette subfamily F member 3" Q9NUQ8 3 184186023-184194012 "Predicted intracellular proteins, Transporters" "Antiviral defense" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036332 Approved Approved Nucleoli,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 39: Non-specific - Basic cellular processes" Cytosol Nucleoli "HPA036332: AB_10603571" "unprognostic (1.70e-2)" "unprognostic (1.16e-1)" "unprognostic (3.10e-2)" "unprognostic (3.81e-2)" "unprognostic (4.11e-1)" "unprognostic (1.12e-1)" "prognostic unfavorable (4.16e-5)" "unprognostic (5.18e-2)" "unprognostic (5.97e-2)" "unprognostic (2.67e-1)" "unprognostic (1.01e-1)" "unprognostic (5.52e-2)" "unprognostic (1.85e-2)" "unprognostic (3.72e-2)" "unprognostic (1.44e-1)" "unprognostic (1.94e-2)" "unprognostic (6.53e-2)" 16.1 56.1 10.9 13.3 10.9 16.8 15.8 11.8 13.4 18.2 9.6 15.5 15.7 15.5 12.3 20.0 17.0 12.7 28.5 10.9 12.7 19.2 22.7 14.4 17.0 13.9 12.3 20.0 23.6 43.5 21.0 16.4 12.8 16.2 13.6 14.2 26.9 19.6 46.8 19.6 16.3 12.4 9.2 17.8 17.5 16.5 12.4 14.6 17.9 41.3 16.1 17.1 17.6 11.6 49.9 30.2 16.9 32.8 48.1 26.9 33.3 35.2 39.1 46.7 36.5 52.0 19.3 29.8 69.5 38.1 54.9 46.4 26.5 37.1 24.1 38.4 25.5 25.7 26.6 30.8 40.4 29.2 25.2 39.7 33.5 33.1 32.7 27.4 33.8 25.7 24.1 34.9 33.5 60.0 28.7 18.8 25.7 51.1 41.2 28.5 28.1 50.4 25.4 29.6 29.1 16.9 36.5 69.1 33.8 18.3 93.7 25.3 33.5 24.9 27.1 39.5 53.1 39.2 40.5 38.2 38.8 28.7 31.3 8.1 29.1 22.7 32.9 30.4 34.7 23.6 29.0 27.5 25.6 23.8 36.0 29.5 14.6 24.0 32.4 15.8 27.2 37.2 10.9 10.9 11.8 13.4 10.9 12.7 13.9 12.3 12.8 9.2 12.4 11.6 10.2 9.6 2.0 6.2 17.4 14.5 10.0 29.8 9.6 16.7 10.8 6.7 11.6 17.2 19.7 14.7 14.6 36.9 16.2 19.8 29.4 22.5 9.5 11.2 12.0 11.6 11.4 8.6 7.1 22.4 25.5 12.5 13.3 12.0 9.5 16.0 16.8 20.0 21.6 20.2 9.9 13.4 30.5 9.4 6.9 10.2 12.5 12.9 16.0 3.7 22.8 14.7 17.5 6.6 7.3 20.5 9.8 11.7 19.4 9.0 28.6 37.3 14.4 22.3 6.6 11.9 9.5 12.8 17.1 14.5 10.2 43.8 16.6 18.1 14.7 11.7 ABRACL "C6orf115, Costars, HSPC280, PRO2013" ENSG00000146386 "ABRA C-terminal like" Q9P1F3 6 139028745-139043302 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 440.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HL-60: 501.5;NB-4: 530.8;U-937: 515.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030217 Enhanced Approved Nucleoplasm,Cytosol NA NA 9200000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Transcription" "Cluster 32: U-937 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm Cytosol "HPA030217: AB_10602335" "unprognostic (1.10e-2)" "unprognostic (1.63e-1)" "unprognostic (9.30e-2)" "unprognostic (2.28e-1)" "unprognostic (2.13e-1)" "unprognostic (1.72e-1)" "unprognostic (7.93e-3)" "unprognostic (1.37e-1)" "unprognostic (1.50e-1)" "unprognostic (2.21e-1)" "unprognostic (8.17e-2)" "unprognostic (2.16e-1)" "unprognostic (3.07e-3)" "unprognostic (5.90e-3)" "unprognostic (3.63e-2)" "unprognostic (3.29e-2)" "prognostic favorable (1.65e-6)" 20.1 9.6 16.8 73.7 16.2 87.7 44.9 13.5 20.8 20.7 14.7 95.0 74.1 22.0 136.0 42.0 12.4 36.0 13.3 18.6 15.7 50.0 60.7 31.2 123.1 14.7 14.6 4.1 16.1 49.1 14.4 29.1 16.2 16.3 86.5 5.4 40.8 12.2 3.0 38.8 74.4 23.5 14.9 73.9 34.4 32.3 16.4 139.6 42.4 7.5 87.9 79.6 17.1 16.0 76.8 40.7 100.7 94.8 39.7 62.2 110.6 59.7 42.9 44.5 91.2 91.2 87.4 0.4 105.8 59.8 189.5 112.9 90.4 130.0 51.9 204.4 167.4 297.8 20.7 31.6 57.6 501.5 130.5 55.9 108.2 59.9 49.1 79.4 237.5 204.9 38.4 100.4 129.5 162.7 314.2 530.8 120.9 119.1 78.5 199.8 62.3 23.8 121.7 225.0 225.4 24.8 40.5 112.3 194.5 141.9 45.1 369.8 175.7 28.2 24.0 58.9 107.7 54.1 169.2 20.9 35.7 515.5 84.2 232.3 178.0 114.2 161.1 334.3 252.2 93.8 259.3 208.2 193.9 96.9 250.9 235.9 48.8 152.1 514.5 215.9 260.2 347.8 16.8 16.2 13.5 20.8 18.6 15.7 14.7 14.6 16.2 14.9 16.4 16.0 54.2 19.2 22.2 2.0 87.1 139.6 71.4 195.2 108.1 0.3 86.6 67.8 3.8 27.1 126.2 44.1 0.0 77.1 151.3 304.5 60.7 145.3 4.8 85.8 20.1 55.0 43.1 75.7 12.8 145.0 207.7 23.5 55.5 129.0 79.4 59.9 53.6 254.3 353.1 0.0 9.1 116.8 162.8 286.1 133.9 13.7 4.7 187.6 87.2 5.6 167.9 49.8 189.5 1.0 1.0 167.4 250.6 12.8 121.0 47.9 247.5 440.3 74.1 1.3 32.9 7.2 37.3 3.6 7.7 116.6 90.1 48.6 198.5 17.7 123.6 133.8 ABT1 Esf2 ENSG00000146109 "Activator of basal transcription 1" Q9ULW3 6 26596953-26600739 "Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077039 Approved Vesicles NA NA "Cluster 44: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Vesicles "HPA077039: AB_2732328" "unprognostic (1.32e-1)" "unprognostic (3.94e-2)" "unprognostic (3.05e-1)" "unprognostic (1.15e-3)" "unprognostic (1.77e-1)" "unprognostic (7.74e-2)" "unprognostic (2.55e-2)" "unprognostic (2.36e-2)" "unprognostic (1.85e-2)" "prognostic favorable (1.89e-4)" "unprognostic (2.30e-3)" "unprognostic (2.93e-2)" "unprognostic (7.25e-3)" "unprognostic (7.20e-2)" "unprognostic (9.57e-2)" "unprognostic (1.49e-1)" "prognostic favorable (3.80e-4)" 9.3 8.0 6.5 9.5 6.7 23.2 9.3 7.8 7.7 8.9 6.5 10.1 10.0 10.8 6.3 13.9 9.2 5.9 8.7 6.5 6.4 8.2 13.0 7.9 15.8 6.4 6.4 9.2 9.4 8.3 7.3 10.7 6.4 8.2 6.7 4.7 9.0 6.7 9.6 14.3 11.6 5.7 6.4 14.8 9.9 8.0 6.6 13.0 7.3 7.1 10.5 9.3 9.7 6.8 23.3 11.9 16.3 28.4 8.9 9.3 23.9 13.4 13.6 20.0 19.5 21.6 10.0 33.8 30.0 11.1 15.9 14.5 19.0 19.5 11.7 18.9 38.7 22.2 11.2 40.6 14.3 30.6 21.7 12.4 17.9 15.9 9.4 9.3 17.5 26.2 39.3 22.1 11.2 23.6 35.6 39.1 16.8 14.9 15.9 21.4 13.2 35.8 12.5 18.7 21.4 17.2 8.3 21.6 32.9 8.6 20.8 24.6 15.1 15.2 11.2 12.2 27.3 25.8 40.9 30.9 7.2 37.6 23.8 76.1 41.6 53.8 66.1 40.2 63.3 66.5 63.8 66.2 39.7 70.2 67.4 60.8 37.2 57.5 41.7 37.1 76.3 88.1 6.5 6.7 7.8 7.7 6.5 6.4 6.4 6.4 6.4 6.4 6.6 6.8 22.4 16.0 15.5 3.3 41.8 59.9 35.8 65.2 34.1 16.2 23.1 22.2 7.1 21.5 31.8 11.0 2.1 96.0 50.8 16.1 41.1 39.4 39.7 12.1 14.0 31.6 34.0 26.9 4.4 38.7 97.5 21.1 16.8 17.3 29.1 17.7 25.4 21.2 42.2 15.2 4.3 25.3 50.8 21.2 22.6 81.8 27.7 22.2 16.0 2.8 32.3 22.0 78.2 3.5 4.5 35.9 19.5 23.7 29.4 31.6 27.9 24.4 21.8 17.2 19.7 15.1 23.4 29.6 41.2 28.3 59.8 109.5 44.3 24.5 29.5 33.6 AC138647.1 ENSG00000226490 "Novel protein" 8 141514638-141518737 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 12 "brain: 4.0;testis: 9.9" "Group enriched" "Detected in some" 5 "Early spermatids: 226.6;Late spermatids: 66.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "cerebral cortex: 1.2;hypothalamus: 4.0;medulla oblongata: 1.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 4.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 9.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 1.2 0.3 4.0 1.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 226.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 66.1 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ACAD9 "MGC14452, NPD002" ENSG00000177646 "Acyl-CoA dehydrogenase family member 9" Q9H845 3 128879596-128924003 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037716, HPA046720" Supported Enhanced Mitochondria No No "Cluster 14: Monocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA037716: AB_10673638, HPA046720: AB_2679773" "unprognostic (1.04e-1)" "unprognostic (1.28e-2)" "unprognostic (1.15e-1)" "prognostic unfavorable (3.05e-4)" "unprognostic (3.61e-1)" "unprognostic (2.83e-1)" "prognostic unfavorable (3.67e-6)" "unprognostic (1.30e-1)" "unprognostic (3.74e-1)" "unprognostic (3.25e-2)" "unprognostic (1.37e-1)" "unprognostic (6.96e-3)" "prognostic favorable (4.32e-8)" "unprognostic (1.52e-1)" "unprognostic (2.64e-2)" "unprognostic (6.56e-2)" "unprognostic (9.96e-2)" 16.7 20.5 9.0 6.1 8.5 4.7 14.5 9.6 10.2 14.4 9.1 13.6 9.0 14.6 7.7 23.2 12.9 7.3 21.9 8.3 8.7 15.6 20.6 11.0 6.6 8.2 8.7 12.9 14.4 27.7 14.6 8.4 8.4 12.1 9.4 4.1 14.2 12.0 30.4 48.0 11.2 11.1 7.4 12.2 15.9 12.5 8.7 12.1 13.6 28.7 11.2 12.9 14.5 9.0 46.2 22.6 18.0 12.6 28.7 20.7 17.5 22.4 26.2 43.6 36.8 33.3 27.1 33.3 21.1 29.5 29.0 35.5 33.8 45.9 32.8 21.2 23.1 29.3 46.8 24.4 21.6 23.9 10.6 22.5 16.8 23.6 26.7 25.1 35.8 25.2 14.4 11.4 29.5 46.5 36.7 19.0 9.9 49.3 33.8 25.5 17.4 35.1 30.9 25.1 19.0 11.6 37.0 32.9 23.2 17.4 44.5 54.8 18.2 13.2 13.4 14.2 20.3 14.5 5.8 28.3 28.3 21.4 22.7 2.4 15.1 4.9 8.3 18.3 7.8 8.1 7.6 7.3 17.5 5.4 6.2 8.0 0.7 6.8 25.2 9.9 8.3 12.1 9.0 8.5 9.6 10.2 8.3 8.7 8.2 8.7 8.4 7.4 8.7 9.0 10.4 16.0 21.7 13.1 9.3 6.2 11.4 16.7 8.6 14.1 11.9 9.5 30.5 15.7 14.8 14.7 10.4 26.2 10.5 11.7 21.5 20.6 20.2 10.4 11.5 11.2 5.4 14.3 14.3 17.8 18.8 12.9 16.8 12.9 16.5 12.0 15.7 26.7 31.5 10.1 17.7 7.4 16.2 9.5 4.0 17.3 10.2 10.8 16.0 7.5 13.4 15.0 12.3 6.0 12.2 14.1 8.7 14.7 9.5 8.1 9.4 26.3 12.0 11.9 13.1 12.7 14.9 22.6 9.6 13.5 14.2 30.6 8.2 18.1 14.3 8.4 ACBD6 MGC2404 ENSG00000230124 "Acyl-CoA binding domain containing 6" Q9BR61 1 180269653-180502954 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028179, HPA028457" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 23: Testis - Cell cycle regulation" "Cluster 24: NB-4 - Immune response" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm Cytosol "HPA028179: AB_10601788, HPA028457: " "unprognostic (3.12e-1)" "unprognostic (4.38e-2)" "unprognostic (1.66e-1)" "unprognostic (7.66e-2)" "unprognostic (1.48e-1)" "unprognostic (1.66e-1)" "unprognostic (2.93e-3)" "unprognostic (1.75e-2)" "unprognostic (2.03e-2)" "unprognostic (2.73e-2)" "unprognostic (7.05e-2)" "unprognostic (2.11e-1)" "prognostic unfavorable (4.02e-7)" "unprognostic (1.26e-1)" "unprognostic (1.74e-1)" "unprognostic (1.21e-1)" "unprognostic (2.51e-1)" 19.5 19.0 11.5 15.0 11.3 25.9 18.4 14.9 13.8 20.5 10.7 21.1 15.2 21.5 15.1 15.1 17.7 17.7 22.3 10.6 12.3 17.7 15.5 15.2 19.0 10.7 10.5 24.7 19.5 25.0 14.4 28.2 10.7 16.4 13.6 7.2 17.3 17.4 24.0 20.7 13.8 18.5 10.3 17.8 15.4 33.0 11.1 20.5 20.0 20.6 18.1 19.5 17.3 13.5 69.4 56.4 47.6 33.2 33.9 57.4 91.1 31.3 69.7 57.6 52.0 80.1 52.8 60.0 62.2 35.3 27.5 47.0 36.2 62.7 38.3 44.5 56.8 48.3 51.9 48.2 82.2 85.5 41.2 51.1 89.5 35.9 59.0 52.4 66.2 49.9 74.5 48.9 48.4 70.7 68.1 84.1 47.8 53.2 20.3 67.3 38.0 119.4 51.4 40.8 68.0 86.0 44.4 74.6 44.9 48.6 75.6 65.4 50.4 40.8 45.3 49.5 71.0 88.1 55.7 137.4 43.4 50.7 47.7 3.1 13.1 4.4 13.6 20.0 15.4 18.1 11.6 11.8 22.0 11.6 13.9 16.3 0.9 27.3 16.3 17.7 11.7 12.2 11.5 11.3 14.9 13.8 10.6 12.3 10.7 10.5 10.7 10.3 11.1 13.5 31.5 32.1 33.0 60.4 32.7 21.3 29.9 38.7 42.7 64.2 23.6 33.3 42.3 21.5 35.4 16.5 39.6 165.0 38.7 3.8 41.1 43.7 106.9 22.2 38.0 31.9 19.4 25.0 124.9 41.6 41.7 35.6 19.9 23.3 20.2 52.2 23.9 13.4 44.6 52.2 118.1 15.7 34.6 17.8 18.6 59.2 51.3 25.0 37.4 60.9 30.0 37.8 26.8 98.0 109.3 36.2 12.9 50.8 48.4 27.2 19.6 51.2 27.4 6.6 59.2 38.4 53.4 143.6 64.6 40.5 22.4 84.4 29.4 63.2 19.2 24.8 ACE "ACE1, CD143, DCP1" ENSG00000159640 "Angiotensin I converting enzyme" P12821 17 63477061-63498380 "Candidate cardiovascular disease genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 265.1;testis: 101.9" "Group enriched" "Detected in many" 20 "Early spermatids: 543.6;Late spermatids: 1322.9;Proximal enterocytes: 1172.8" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 8.1" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.0" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in many" 4 "ASC TERT1: 63.3;HUVEC TERT2: 33.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002426, CAB002921, HPA029298, HPA069790" Enhanced Approved Vesicles "Secreted to blood" NA NA 104000000 170000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 56: Intestine - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 45: Enterocytes - Digestion" Vesicles "CAB002426: AB_442052, CAB002921: , HPA029298: AB_10960255, HPA069790: AB_2686197" "unprognostic (4.72e-2)" "unprognostic (4.16e-1)" "unprognostic (1.93e-3)" "unprognostic (6.06e-2)" "unprognostic (2.78e-1)" "unprognostic (1.35e-2)" "unprognostic (4.37e-1)" "unprognostic (1.54e-1)" "unprognostic (1.56e-1)" "unprognostic (1.25e-2)" "unprognostic (3.13e-2)" "unprognostic (2.38e-1)" "unprognostic (7.66e-2)" "unprognostic (9.07e-2)" "unprognostic (1.66e-1)" "unprognostic (1.08e-1)" "unprognostic (2.76e-2)" 13.4 4.9 1.7 4.8 8.1 0.1 8.1 0.2 2.5 18.1 0.5 11.2 176.4 8.1 3.5 4.1 6.3 8.2 10.4 1.3 1.0 10.8 1.9 49.0 4.9 1.3 0.9 1.9 6.2 18.7 9.2 11.6 1.3 8.9 6.1 0.4 7.6 23.8 16.1 3.8 265.1 9.6 0.8 2.8 8.3 101.9 2.0 0.8 19.2 10.0 2.1 5.5 3.8 1.1 0.0 0.0 0.0 0.0 2.6 63.3 0.6 2.4 4.7 0.0 0.0 0.9 5.1 1.3 1.8 11.4 0.1 0.0 3.1 0.0 0.0 0.0 1.4 6.6 0.0 0.0 1.4 0.0 0.0 4.2 0.0 0.1 0.0 1.2 33.8 0.0 5.8 0.0 0.1 1.1 0.0 1.4 0.4 11.7 0.7 0.1 0.5 0.9 0.0 0.0 8.2 5.6 0.0 0.0 0.0 1.3 2.9 0.4 0.0 0.1 0.2 0.5 0.1 0.0 0.0 0.0 1.0 0.0 0.5 0.0 0.0 0.0 0.1 0.1 0.2 1.0 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 1.7 8.1 0.2 2.5 1.3 1.0 1.3 0.9 1.3 0.8 2.0 1.1 50.0 0.0 3.3 0.0 0.5 1.5 2.6 0.1 1.2 4.0 3.6 1.9 2.1 1.5 0.7 0.0 0.0 0.1 0.3 11.9 0.0 5.9 543.6 10.8 8.0 34.7 18.0 0.0 4.7 0.4 0.1 11.5 2.0 36.3 7.0 24.1 3.6 0.8 4.2 0.0 1.8 39.8 0.0 33.7 3.5 1322.9 4.4 13.6 3.6 4.7 0.0 1.8 0.0 1.0 0.2 0.7 40.9 2.6 0.1 4.2 1172.8 21.7 0.0 1.1 0.0 2.0 4.2 13.5 6.4 0.2 0.1 0.1 2.2 0.3 26.2 2.1 ACKR1 "CCBP1, CD234, DARC, Dfy, FY, GPD" ENSG00000213088 "Atypical chemokine receptor 1 (Duffy blood group)" Q16570 1 159203307-159206500 "Blood group antigen proteins, CD markers, G-protein coupled receptors, Predicted membrane proteins" "Blood group antigen, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 320.5;breast: 278.2" "Group enriched" "Detected in many" 5 "Adipocytes: 383.6;Endothelial cells: 523.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "HEL: 44.4;HSkMC: 30.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016421, HPA017672" Enhanced NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 36: HEL - Hemostasis" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA016421: AB_1849219, HPA017672: AB_1849221" "unprognostic (8.74e-3)" "prognostic favorable (2.52e-5)" "unprognostic (9.73e-2)" "unprognostic (1.91e-1)" "unprognostic (2.34e-3)" "unprognostic (3.84e-3)" "prognostic favorable (1.48e-4)" "unprognostic (7.80e-2)" "unprognostic (2.22e-1)" "unprognostic (3.46e-2)" "unprognostic (1.65e-3)" "unprognostic (1.81e-1)" "unprognostic (3.82e-3)" "unprognostic (5.17e-3)" "unprognostic (2.40e-1)" "prognostic unfavorable (9.76e-4)" "unprognostic (2.30e-2)" 320.5 13.4 17.7 42.0 21.8 14.5 278.2 34.6 25.5 141.7 21.6 67.0 15.3 125.0 21.5 63.6 121.2 59.2 42.2 18.4 18.6 34.5 1.8 146.8 49.3 21.4 17.7 21.4 15.8 9.7 11.6 10.4 23.2 72.9 19.4 23.7 61.3 24.5 51.7 85.3 60.9 107.7 24.9 82.1 57.0 8.6 17.0 33.2 47.7 30.2 40.8 112.4 113.1 22.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 44.4 0.0 0.0 5.5 0.0 0.0 30.7 0.0 0.0 3.9 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 1.5 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.7 21.8 34.6 25.5 18.4 18.6 21.4 17.7 23.2 24.9 17.0 22.0 383.6 6.4 10.8 1.6 1.0 0.0 1.7 0.0 2.8 78.4 3.6 3.7 15.1 0.0 1.8 0.0 2.1 0.4 0.8 0.0 0.0 0.0 2.2 0.4 1.0 523.8 0.0 81.3 3.6 9.8 0.2 18.9 0.0 0.4 5.1 0.0 7.5 0.0 1.1 6.7 3.2 0.0 0.0 0.8 0.0 3.7 1.2 2.2 0.0 1.0 0.0 5.9 0.0 0.5 0.3 0.0 0.0 0.4 0.1 2.2 0.0 0.1 0.7 3.7 0.0 3.9 4.5 0.2 0.5 4.0 0.0 0.1 1.1 0.1 0.0 2.3 ACOT2 "Mte1, ZAP128" ENSG00000119673 "Acyl-CoA thioesterase 2" P49753 14 73567620-73575658 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 118.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 50.0;Exocrine glandular cells: 33.2;Proximal tubular cells: 36.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 62.4" "HPA043705, HPA060170" Enhanced Approved Mitochondria NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 8: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 59: Non-specific - Transcription" Mitochondria "HPA043705: AB_2678626, HPA060170: AB_2732642" "unprognostic (4.44e-3)" "unprognostic (1.68e-2)" "unprognostic (3.17e-1)" "unprognostic (8.66e-2)" "unprognostic (1.78e-1)" "unprognostic (1.55e-1)" "unprognostic (2.78e-2)" "unprognostic (6.61e-2)" "unprognostic (4.10e-2)" "unprognostic (9.21e-2)" "unprognostic (6.42e-2)" "unprognostic (1.64e-1)" "prognostic favorable (2.28e-6)" "unprognostic (1.66e-3)" "unprognostic (1.04e-1)" "unprognostic (1.52e-1)" "unprognostic (4.35e-1)" 92.3 47.7 10.0 7.0 10.3 5.6 48.9 9.2 12.4 17.1 12.2 42.2 24.7 42.9 10.7 10.9 24.1 6.1 94.5 10.1 9.5 49.4 118.9 17.3 4.7 8.8 9.4 11.7 12.8 22.4 8.3 4.4 8.2 17.8 11.1 4.1 17.8 11.1 114.0 13.1 24.5 22.8 9.2 11.4 22.5 12.0 13.0 3.7 14.5 50.0 3.3 31.2 13.3 9.0 22.8 25.0 4.9 22.1 21.3 7.9 1.0 13.7 31.5 21.9 28.6 18.1 12.6 0.1 9.7 7.0 10.3 12.7 0.0 1.2 11.4 33.1 31.6 16.0 7.6 62.4 14.5 0.1 43.3 19.5 0.0 7.6 0.1 21.0 9.5 0.0 0.0 0.1 18.7 7.4 2.5 18.2 7.5 2.3 37.8 37.2 21.9 0.3 8.0 9.5 21.6 27.3 33.1 24.3 29.6 2.1 51.1 12.7 17.0 17.9 47.2 11.8 13.0 0.0 0.1 9.5 15.8 0.1 18.2 3.5 5.9 3.1 22.1 7.0 15.8 15.0 20.2 16.6 21.9 12.4 17.8 19.9 0.2 15.3 6.5 13.6 31.3 13.6 10.0 10.3 9.2 12.4 10.1 9.5 8.8 9.4 8.2 9.2 13.0 9.0 4.3 0.0 6.4 3.3 6.6 1.7 1.0 5.9 16.5 1.1 5.2 4.2 50.0 7.2 3.0 7.3 10.4 6.1 3.0 20.1 13.7 20.9 1.5 1.4 1.9 4.0 15.7 8.4 2.9 33.2 3.2 7.0 11.7 2.1 13.4 1.9 4.2 27.7 14.9 1.7 3.1 15.5 10.2 3.8 1.6 1.1 5.9 5.6 5.4 1.0 18.5 5.5 7.2 3.0 1.7 21.8 8.6 8.2 7.9 0.4 27.5 36.5 3.3 4.9 6.6 1.4 9.8 0.3 4.8 8.5 0.4 8.2 5.8 1.7 18.8 0.4 ACSL4 "ACS4, FACL4, LACS4, MRX63, MRX68" ENSG00000068366 "Acyl-CoA synthetase long chain family member 4" O60488 X 109624244-109733403 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Alport syndrome, Deafness, Disease variant, Elliptocytosis, Hereditary hemolytic anemia, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 184.3;Glandular and luminal cells: 208.8;granulocytes: 633.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 360.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000286, HPA005552" Supported Approved "Golgi apparatus,Mitochondria" NA NA 16000 "Cluster 2: Granulocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "Golgi apparatus" Mitochondria "HPA000286: AB_2665966, HPA005552: AB_1078774" "unprognostic (9.13e-2)" "unprognostic (3.38e-1)" "unprognostic (1.39e-1)" "unprognostic (2.61e-1)" "unprognostic (2.55e-1)" "unprognostic (2.94e-2)" "unprognostic (5.32e-2)" "unprognostic (4.14e-3)" "unprognostic (1.92e-1)" "unprognostic (9.45e-2)" "unprognostic (1.92e-2)" "unprognostic (1.21e-1)" "unprognostic (1.64e-2)" "unprognostic (1.81e-1)" "unprognostic (4.78e-1)" "unprognostic (3.29e-2)" "prognostic favorable (5.73e-4)" 44.2 40.6 11.9 38.8 14.1 16.2 19.8 13.2 14.8 48.2 5.6 12.7 15.4 19.2 17.7 15.8 13.4 29.2 29.4 16.5 23.7 46.4 13.9 39.0 24.6 17.6 20.8 14.9 11.9 19.8 9.2 21.4 21.3 13.4 13.6 24.7 10.6 15.2 42.6 9.9 13.4 22.0 13.7 22.2 19.3 26.8 14.6 20.3 18.6 16.9 18.5 68.0 10.6 18.9 67.3 21.3 24.2 28.3 97.8 61.6 20.3 94.0 107.6 91.0 97.4 21.1 45.0 46.2 35.4 71.7 100.9 19.4 22.4 92.0 143.0 15.7 23.3 181.4 26.6 223.3 44.8 44.8 360.0 51.4 36.7 103.6 74.0 50.2 71.8 25.5 5.6 54.2 100.7 4.7 40.7 60.7 31.6 15.2 37.2 26.4 45.4 39.6 136.3 20.9 15.2 12.3 109.3 0.4 63.2 49.0 1.9 45.8 128.5 81.1 22.6 129.3 85.9 28.1 31.7 41.2 139.7 97.8 52.2 32.5 10.9 35.0 4.2 15.5 3.2 3.3 3.9 3.5 10.6 3.1 3.0 3.8 29.6 4.0 19.4 4.0 6.7 6.5 11.9 14.1 13.2 14.8 16.5 23.7 17.6 20.8 21.3 13.7 14.6 18.9 27.9 76.9 184.3 29.0 19.5 22.3 25.7 20.0 81.4 44.2 7.3 8.1 37.2 15.7 40.1 73.5 2.1 7.3 18.3 0.8 50.9 27.7 1.4 79.5 27.0 29.8 7.7 26.1 76.7 25.4 36.9 46.0 7.1 208.8 633.8 151.6 18.2 44.2 23.9 6.7 78.3 5.7 2.0 64.9 59.1 4.9 5.6 67.8 16.0 57.1 70.4 10.9 8.2 71.4 116.4 32.3 3.0 10.1 36.1 19.4 0.7 12.4 12.2 16.7 0.0 20.0 27.9 3.7 5.3 10.1 8.1 31.6 25.2 34.9 2.7 18.4 ACTL10 C20orf134 ENSG00000182584 "Actin like 10" Q5JWF8 20 33666498-33668525 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 19 "testis: 60.4" "Group enriched" "Detected in many" 37 "Early spermatids: 379.0;Late spermatids: 534.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 1.8;HaCaT: 1.9;Karpas-707: 1.8;OE19: 2.0;RPMI-8226: 3.2;SK-BR-3: 2.6" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 83: Testis - Spermatogenesis" "Cluster 25: RPMI-8226 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (5.69e-3)" "unprognostic (3.62e-1)" "unprognostic (3.79e-2)" "unprognostic (1.58e-1)" "unprognostic (5.91e-3)" "unprognostic (4.00e-3)" "unprognostic (1.80e-1)" "unprognostic (1.72e-1)" "unprognostic (5.31e-2)" "unprognostic (2.35e-1)" "unprognostic (2.58e-1)" "unprognostic (2.67e-3)" "unprognostic (5.90e-2)" "unprognostic (1.15e-1)" "unprognostic (1.27e-1)" "unprognostic (1.14e-1)" "unprognostic (8.61e-2)" 0.5 0.6 0.5 0.2 0.2 0.0 0.8 0.0 0.6 0.7 0.4 1.1 0.6 0.9 0.0 1.7 0.9 0.2 0.4 0.4 0.0 1.0 0.4 0.6 0.2 1.0 0.1 1.0 3.2 0.2 0.7 0.0 0.1 2.0 0.2 0.0 1.7 0.3 0.2 1.1 1.3 0.1 0.0 1.2 1.2 60.4 0.1 0.2 1.1 0.0 0.2 1.0 0.9 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.1 0.0 0.1 1.1 1.8 0.6 1.0 0.3 0.0 1.9 0.0 0.5 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.6 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.1 1.8 0.0 0.9 0.0 0.0 0.0 2.0 0.3 0.0 0.1 3.2 0.4 0.6 0.6 0.1 0.7 2.6 0.0 0.0 1.1 0.0 0.3 0.1 0.0 0.2 0.0 0.7 1.5 0.1 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.2 0.2 0.2 0.3 0.2 0.0 0.0 0.6 0.1 0.1 0.4 0.0 0.5 0.2 0.0 0.6 0.4 0.0 1.0 0.1 0.1 0.0 0.1 0.4 0.6 0.0 0.5 0.0 0.9 0.5 4.6 1.0 3.4 0.4 2.8 2.3 0.5 4.3 1.3 1.8 0.0 0.3 1.6 3.3 1.9 4.8 379.0 1.3 1.3 1.2 1.2 2.7 0.0 7.6 0.8 0.9 5.1 1.9 0.0 0.2 0.4 0.4 0.9 0.0 0.0 5.3 12.2 1.0 0.4 534.2 5.3 3.7 1.8 0.0 1.9 1.4 7.2 0.0 0.3 4.0 2.7 3.0 4.4 2.6 2.9 2.0 0.5 0.2 0.0 1.6 1.2 7.9 1.5 3.0 1.3 0.1 1.9 1.7 3.7 2.8 ACTL7B Tact1 ENSG00000148156 "Actin like 7B" Q9Y614 9 108854588-108855986 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1099 "testis: 118.8" "Group enriched" "Detected in some" 19 "Early spermatids: 1697.8;Late spermatids: 449.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA021803, HPA024664" Enhanced NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 29: Early spermatids - Spermatogenesis" "HPA021803: AB_1844551, HPA024664: AB_1844552" "unprognostic (7.64e-2)" "unprognostic (1.62e-1)" "unprognostic (3.09e-1)" "unprognostic (3.83e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 118.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1697.8 0.2 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 449.1 9.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 54.6 4.9 0.0 0.0 0.0 0.0 0.3 0.0 0.1 ACTN4 FSGS1 ENSG00000130402 "Actinin alpha 4" O43707 19 38647649-38731589 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" Actin-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 626.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "A549: 947.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001873, HPA006035" Supported Approved "Nuclear bodies,Actin filaments,Cytosol" NA NA 71000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 72: Non-specific - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear bodies, Actin filaments" Cytosol "HPA001873: AB_1078096, HPA006035: AB_1078095" "unprognostic (1.03e-1)" "unprognostic (6.34e-2)" "unprognostic (2.97e-2)" "unprognostic (2.52e-2)" "unprognostic (2.37e-1)" "unprognostic (3.34e-2)" "unprognostic (2.21e-2)" "prognostic unfavorable (8.82e-4)" "unprognostic (1.70e-1)" "unprognostic (5.85e-3)" "prognostic unfavorable (5.65e-4)" "unprognostic (2.99e-1)" "prognostic favorable (5.25e-5)" "unprognostic (6.59e-2)" "unprognostic (1.91e-1)" "unprognostic (6.75e-3)" "unprognostic (6.52e-2)" 176.5 160.8 22.9 63.9 42.0 74.2 151.4 42.9 42.2 165.2 58.5 168.5 128.7 269.4 11.8 232.8 163.2 46.8 89.0 19.5 27.8 166.7 85.0 174.7 37.5 45.9 42.4 102.5 90.6 42.2 80.0 85.7 44.8 115.6 42.2 26.0 148.1 59.0 52.2 183.4 150.3 73.1 30.2 118.1 120.9 23.6 38.1 18.5 105.4 18.8 24.2 150.2 181.3 63.4 364.6 947.0 92.9 48.6 37.7 50.6 237.2 198.7 162.5 178.8 143.9 335.9 265.1 99.0 409.1 260.6 117.4 185.1 57.4 203.8 38.3 238.3 69.5 139.7 356.1 240.4 103.4 101.7 145.2 95.3 63.4 157.5 79.6 146.9 116.4 26.3 165.0 71.8 127.5 221.2 27.2 44.1 78.4 197.8 177.3 89.5 109.4 43.8 174.6 396.3 83.0 49.8 366.3 210.5 94.7 64.0 94.5 78.8 309.7 249.3 138.7 135.3 476.1 44.1 84.5 67.8 231.7 90.6 476.7 7.6 8.1 17.8 13.2 7.7 9.8 3.2 5.7 13.2 7.0 3.0 0.9 4.4 16.9 24.8 6.7 10.8 9.5 10.6 22.9 42.0 42.9 42.2 19.5 27.8 45.9 42.4 44.8 30.2 38.1 63.4 315.2 179.5 120.0 21.5 45.8 234.8 266.4 155.1 153.7 25.6 134.0 148.1 9.2 143.0 119.4 152.6 14.6 123.7 150.7 626.1 19.6 413.5 2.5 272.0 145.7 206.2 162.0 59.3 46.0 419.3 256.7 77.3 219.7 346.4 73.5 75.9 130.6 108.5 72.6 23.5 22.6 365.5 73.2 65.9 103.7 4.5 41.3 75.4 46.2 48.7 162.2 122.4 120.5 35.2 83.6 532.3 425.2 71.5 91.2 322.1 315.5 104.0 122.1 32.3 190.7 97.2 251.0 36.2 23.7 189.3 202.7 168.0 119.4 115.3 280.6 284.7 ACTR3 ARP3 ENSG00000115091 "Actin related protein 3" P61158 2 113890063-113962596 "Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005085, HPA047016, HPA051683" Approved NA NA 25000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 10: Non-specific - Unknown function" "CAB005085: AB_2289106, HPA047016: AB_2679903, HPA051683: AB_2681573" "unprognostic (7.28e-2)" "prognostic unfavorable (6.52e-5)" "unprognostic (2.03e-2)" "unprognostic (1.01e-3)" "unprognostic (1.14e-1)" "unprognostic (1.05e-2)" "prognostic unfavorable (7.76e-5)" "unprognostic (9.27e-3)" "unprognostic (1.63e-1)" "unprognostic (2.50e-2)" "unprognostic (2.74e-2)" "unprognostic (1.56e-1)" "prognostic unfavorable (3.81e-5)" "unprognostic (2.57e-1)" "unprognostic (2.54e-2)" "unprognostic (3.44e-2)" "unprognostic (4.44e-1)" 97.5 125.3 29.9 229.7 36.4 216.5 64.5 37.6 41.0 62.7 52.4 129.3 107.4 78.1 47.2 167.1 58.1 84.4 71.7 48.0 41.9 79.4 89.9 97.9 291.2 46.4 38.2 46.4 64.3 54.7 23.1 101.4 41.7 71.3 125.1 31.7 64.3 83.6 47.8 77.7 119.0 137.0 36.2 155.8 113.1 84.8 39.0 185.8 67.3 49.8 331.3 153.6 67.1 46.7 377.8 179.1 249.4 170.6 178.0 251.7 259.9 518.7 395.0 369.7 349.1 379.9 233.6 538.7 590.6 487.9 497.1 200.0 262.3 286.5 486.7 806.2 135.6 502.7 210.2 296.2 314.8 474.0 879.1 227.1 220.8 484.9 316.5 216.1 348.6 207.1 273.9 393.8 493.1 153.2 429.7 204.5 187.2 254.8 297.5 328.8 246.8 273.4 381.0 348.9 124.0 124.1 263.0 269.7 330.6 188.7 112.7 387.7 514.6 440.9 288.3 205.6 451.5 208.5 446.5 635.4 385.5 304.2 417.7 753.0 478.9 1048.4 464.4 728.1 381.6 455.9 424.6 460.6 634.4 385.0 371.4 437.9 777.1 479.9 887.7 191.4 587.0 1265.4 29.9 36.4 37.6 41.0 48.0 41.9 46.4 38.2 41.7 36.2 39.0 46.7 113.7 89.8 64.1 26.4 254.0 331.9 369.7 139.1 93.9 32.0 57.5 48.9 68.5 57.2 125.4 68.0 8.4 144.6 196.5 164.4 129.1 220.8 113.6 109.2 100.8 138.9 85.3 154.8 40.1 154.8 316.6 101.4 122.9 171.0 267.5 88.4 81.0 72.9 339.2 38.7 40.4 120.2 105.8 201.4 413.7 108.3 45.4 288.1 112.1 69.3 316.5 46.7 286.3 58.3 67.6 177.0 168.1 73.0 158.7 181.7 103.3 132.4 117.7 19.5 65.7 58.5 194.1 207.1 74.7 173.4 353.8 205.6 264.4 242.2 120.3 314.1 ACYP1 ENSG00000119640 "Acylphosphatase 1" P07311 14 75053237-75069483 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Respiratory ciliated cells: 137.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034944 Approved Approved Nucleoplasm,Cytosol NA NA 89000 "Cluster 27: Non-specific - Gene expression" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 49: Ciliated cells - Cilium organization" Cytosol Nucleoplasm "HPA034944: AB_10669898" "prognostic favorable (1.17e-4)" "unprognostic (3.83e-3)" "unprognostic (1.92e-1)" "unprognostic (5.90e-2)" "unprognostic (1.26e-1)" "unprognostic (1.85e-1)" "prognostic unfavorable (6.14e-7)" "unprognostic (5.48e-2)" "unprognostic (4.40e-1)" "unprognostic (1.64e-2)" "unprognostic (1.37e-3)" "unprognostic (3.56e-2)" "unprognostic (4.74e-2)" "unprognostic (6.69e-3)" "unprognostic (9.39e-2)" "unprognostic (1.07e-1)" "unprognostic (5.32e-3)" 13.7 38.4 46.2 15.2 48.6 21.1 22.1 49.9 65.5 17.3 50.8 21.5 15.6 14.4 36.7 20.8 29.6 10.2 17.0 45.0 54.0 29.1 9.6 19.7 27.7 50.7 49.7 13.6 12.4 21.1 36.5 15.3 51.8 17.3 26.9 44.0 15.8 15.0 34.0 35.0 21.1 15.6 46.6 16.5 19.3 26.9 50.4 39.7 30.1 21.1 28.1 16.1 17.6 56.0 78.9 43.1 60.9 37.4 24.5 26.6 32.6 44.7 17.2 45.5 63.5 42.8 86.9 86.5 26.4 18.2 25.7 68.1 39.9 19.1 73.8 127.8 49.3 57.6 123.6 32.1 14.3 36.6 56.8 14.9 27.7 61.5 30.0 28.8 60.0 80.9 45.2 103.0 60.0 52.3 82.7 67.7 18.6 67.6 40.8 64.7 80.8 41.2 62.2 39.0 112.0 44.5 29.5 20.8 74.2 29.1 44.5 35.4 27.3 29.5 55.6 61.3 48.4 23.8 52.4 94.6 46.1 42.5 32.8 5.3 2.8 17.5 10.9 6.2 12.7 13.7 18.3 12.9 5.1 14.1 15.4 14.5 1.2 14.0 10.5 10.3 24.6 6.7 46.2 48.6 49.9 65.5 45.0 54.0 50.7 49.7 51.8 46.6 50.4 56.0 18.5 6.4 9.1 17.0 18.2 28.7 44.4 54.1 30.1 38.6 20.8 24.0 21.2 31.5 28.9 66.2 12.5 27.3 18.7 24.5 39.2 20.6 31.6 89.2 18.4 26.5 30.1 47.5 17.8 18.7 33.7 22.7 13.7 17.8 12.0 19.8 10.4 5.7 22.3 43.7 25.0 25.2 73.2 6.6 11.7 11.0 16.8 12.3 39.2 15.9 10.1 23.2 16.5 16.1 44.4 20.2 20.6 16.6 16.9 20.2 16.7 22.3 137.9 32.4 26.3 11.1 31.5 89.8 14.1 23.8 24.0 13.7 22.3 20.4 33.8 34.4 ADAM15 MDC15 ENSG00000143537 "ADAM metallopeptidase domain 15" Q13444 1 155050566-155062775 "Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Cell adhesion, Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 164.5;Extravillous trophoblasts: 172.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 39.1;intermediate monocyte: 26.5;myeloid DC: 64.0" "Group enriched" "Detected in all" 5 "dendritic cells: 64.0;monocytes: 39.1" "Cell line enhanced" "Detected in many" "PC-3: 329.5;RPMI-8226: 361.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011633, HPA072878" Uncertain Uncertain Vesicles NA NA 640000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA011633: AB_1844574, HPA072878: " "unprognostic (6.35e-3)" "unprognostic (1.51e-1)" "unprognostic (1.60e-1)" "unprognostic (7.60e-2)" "prognostic unfavorable (5.83e-5)" "unprognostic (2.09e-1)" "prognostic unfavorable (3.49e-4)" "unprognostic (2.07e-2)" "unprognostic (1.09e-1)" "unprognostic (1.16e-1)" "unprognostic (1.06e-2)" "unprognostic (2.70e-1)" "prognostic unfavorable (5.64e-9)" "unprognostic (3.35e-2)" "unprognostic (6.20e-2)" "unprognostic (2.04e-2)" "unprognostic (7.40e-2)" 70.1 18.5 12.5 21.4 16.0 34.1 64.7 16.9 13.9 40.3 7.1 38.3 16.4 42.5 7.6 79.1 41.5 21.6 63.1 10.5 13.8 32.4 15.1 50.0 10.0 20.2 15.1 25.5 25.5 30.0 14.1 39.1 16.8 40.0 23.8 3.4 45.3 16.7 22.7 107.9 31.3 38.6 17.3 28.8 44.2 4.9 17.1 7.3 31.6 32.4 13.6 38.9 57.3 18.0 112.0 35.0 7.0 153.2 54.9 45.6 66.3 48.2 60.9 60.1 40.5 25.9 63.3 30.9 210.7 63.5 26.7 135.9 34.5 147.9 15.8 14.3 44.9 7.6 63.1 25.3 95.5 63.4 7.9 48.7 153.8 60.5 86.6 82.6 274.7 9.3 11.9 124.8 45.2 64.7 0.5 47.1 21.6 193.4 329.5 10.0 20.5 361.8 43.7 29.7 20.8 44.7 105.2 131.2 41.8 10.7 194.8 38.9 205.1 58.6 24.6 58.9 54.1 13.9 11.7 13.7 42.7 47.6 65.4 0.0 39.1 0.8 9.5 26.5 6.5 2.0 4.7 5.6 64.0 2.1 2.0 2.5 1.4 1.6 6.2 5.3 8.9 22.8 12.5 16.0 16.9 13.9 10.5 13.8 20.2 15.1 16.8 17.3 17.1 18.0 164.5 3.2 6.7 8.8 6.6 48.9 30.4 81.6 47.8 9.7 34.6 20.7 11.5 35.8 38.3 9.2 29.2 13.0 8.1 100.4 0.0 33.4 1.7 13.3 9.2 120.8 12.7 4.6 8.1 25.5 172.4 19.8 85.6 15.4 1.3 8.5 62.2 19.9 31.7 6.7 9.8 80.7 18.3 65.0 43.6 1.3 17.4 27.2 14.2 15.9 28.8 8.8 13.4 9.0 16.8 42.1 50.9 18.0 8.0 55.2 47.4 2.6 22.9 17.0 13.1 15.7 14.5 0.8 6.4 91.2 57.1 17.8 8.6 2.7 76.9 40.0 ADAM18 "ADAM27, tMDCIII" ENSG00000168619 "ADAM metallopeptidase domain 18" Q9Y3Q7 8 39584489-39730065 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 74 "testis: 9.2" "Cell type enhanced" "Detected in some" "Early spermatids: 63.5;Late spermatids: 26.8;Spermatocytes: 141.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Intracellular and membrane" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (2.10e-4)" "unprognostic (1.18e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 63.5 0.1 0.0 0.1 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 26.8 2.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.1 141.1 3.1 0.0 0.0 2.5 0.0 0.0 0.0 0.0 ADAM30 svph4 ENSG00000134249 "ADAM metallopeptidase domain 30" Q9UKF2 1 119893533-119896515 "Plasma proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 259 "testis: 25.9" "Group enriched" "Detected in some" 5 "Early spermatids: 77.4;Spermatocytes: 60.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA026080 Uncertain NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA026080: AB_1844581" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 77.4 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.6 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.8 0.0 60.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 ADAM32 ENSG00000197140 "ADAM metallopeptidase domain 32" Q8TC27 8 39106990-39284917 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "testis: 27.4" "Cell type enhanced" "Detected in many" "Early spermatids: 189.0;Excitatory neurons: 37.3;Late spermatids: 50.5;Spermatocytes: 99.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 1.0;MCF7: 1.1;U-2 OS: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA044156, HPA062151" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 11: Basophils - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles Nucleoplasm "HPA044156: AB_10796798, HPA062151: AB_2684699" "unprognostic (2.13e-1)" "unprognostic (6.92e-2)" "unprognostic (4.63e-3)" "unprognostic (8.99e-2)" "unprognostic (1.48e-1)" "unprognostic (1.52e-2)" "unprognostic (5.66e-3)" "unprognostic (1.49e-1)" "unprognostic (2.05e-1)" "unprognostic (1.12e-1)" "unprognostic (2.50e-1)" "unprognostic (3.38e-2)" "unprognostic (1.13e-7)" "unprognostic (3.42e-1)" "unprognostic (4.90e-2)" "unprognostic (8.34e-3)" "unprognostic (7.82e-2)" 1.0 1.0 1.0 0.2 0.9 0.4 1.0 3.2 1.5 0.6 0.0 0.5 0.0 0.4 0.6 0.2 0.5 0.4 0.7 0.9 1.3 0.2 0.0 0.3 0.1 0.1 0.5 0.6 1.8 0.0 0.4 0.1 0.4 0.6 0.4 0.9 0.5 0.3 0.2 0.7 0.2 0.1 0.1 0.7 0.3 27.4 1.0 0.0 0.3 0.1 0.1 0.5 0.4 1.3 0.2 0.4 0.0 0.2 0.6 0.0 0.0 0.4 0.1 0.4 0.2 0.1 0.9 0.0 0.1 0.7 0.0 0.0 0.1 0.0 0.5 0.0 0.1 0.0 1.0 0.1 0.0 0.0 0.2 0.9 0.0 0.0 0.0 0.5 0.0 0.1 0.1 0.2 0.5 1.1 0.1 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.1 0.0 0.2 0.0 0.1 0.3 0.0 0.0 0.7 1.3 0.0 0.5 0.0 0.1 0.0 0.2 0.0 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.4 0.0 0.0 0.0 0.0 1.0 0.9 3.2 1.5 0.9 1.3 0.1 0.5 0.4 0.1 1.0 1.3 1.0 0.0 0.0 11.8 0.0 0.9 1.1 0.7 0.6 8.2 2.5 2.3 1.7 1.5 0.4 1.8 18.8 0.3 0.1 0.4 0.0 0.4 189.0 5.7 3.6 1.0 4.2 0.0 37.3 1.3 0.2 2.4 0.0 9.8 0.0 3.3 0.7 0.4 0.5 0.0 29.8 1.1 0.0 0.0 1.0 50.5 2.8 0.6 0.0 9.4 0.1 1.0 0.0 18.6 17.6 2.8 0.1 3.0 0.1 1.7 0.0 0.2 1.4 3.8 0.0 3.4 0.9 99.9 2.9 0.5 0.0 0.1 0.2 3.7 1.4 1.5 ADAMTS1 "C3-C5, KIAA1346, METH1" ENSG00000154734 "ADAM metallopeptidase with thrombospondin type 1 motif 1" Q9UHI8 21 26835755-26845409 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Heparin-binding, Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 314.4" "Cell type enhanced" "Detected in many" "Adipocytes: 365.2;Endometrial stromal cells: 235.3;Endothelial cells: 275.9;Extravillous trophoblasts: 240.8;Fibroblasts: 243.9;Sertoli cells: 210.4;Smooth muscle cells: 452.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "gdT-cell: 4.5;NK-cell: 6.6" "Group enriched" "Detected in many" 56 "NK-cells: 6.6;T-cells: 4.5" "Cell line enhanced" "Detected in many" "ASC diff: 382.0;BJ: 451.4;hTEC/SVTERT24-B: 250.0;hTERT-HME1: 248.2;LHCN-M2: 295.3;RPTEC TERT1: 343.9" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 4 "spinal cord: 35.6" "CAB016394, HPA031498" Approved Approved "Plasma membrane" "Secreted to extracellular matrix" NA NA 4100000 "Cluster 40: NK-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" "CAB016394: AB_626637, HPA031498: AB_2673907" "unprognostic (6.82e-2)" "unprognostic (1.35e-1)" "unprognostic (1.21e-1)" "unprognostic (1.64e-1)" "unprognostic (1.18e-2)" "prognostic unfavorable (5.13e-4)" "unprognostic (1.03e-1)" "unprognostic (3.28e-1)" "unprognostic (2.37e-2)" "unprognostic (5.39e-2)" "unprognostic (1.75e-1)" "unprognostic (4.55e-2)" "unprognostic (9.70e-3)" "unprognostic (8.27e-3)" "unprognostic (1.12e-1)" "unprognostic (6.76e-2)" "unprognostic (1.57e-1)" 234.6 46.4 22.2 71.3 24.9 1.4 94.1 20.8 28.9 87.4 22.3 54.6 8.7 97.1 9.0 82.6 161.2 111.8 95.9 21.5 23.5 76.0 39.0 79.7 10.1 24.8 25.5 314.4 29.4 18.5 25.5 245.1 25.2 88.2 59.3 15.6 19.2 13.9 48.9 21.9 44.6 162.6 25.3 13.9 56.0 8.2 26.4 12.2 50.1 40.3 5.4 143.1 50.6 30.5 0.1 0.0 6.8 0.1 382.0 104.9 21.8 451.4 199.6 90.4 61.1 0.0 0.0 0.0 29.5 120.1 2.0 9.2 4.6 23.6 150.0 0.4 120.3 0.0 29.7 0.1 85.6 15.5 0.0 103.0 0.3 250.0 248.2 15.1 35.4 3.7 7.3 0.0 295.3 0.0 1.7 0.3 21.9 0.0 14.5 0.0 151.6 0.6 343.9 25.1 0.2 32.7 21.4 0.0 2.2 16.0 0.2 3.8 34.9 99.6 4.3 156.0 63.1 0.5 0.0 0.0 80.8 0.5 29.7 0.0 0.0 0.0 4.5 0.0 0.5 0.0 0.2 0.4 0.0 0.0 0.1 0.7 0.0 6.6 0.0 0.0 0.0 0.8 22.2 24.9 20.8 28.9 21.5 23.5 24.8 25.5 25.2 25.3 26.4 30.5 365.2 6.4 22.4 2.9 0.5 121.2 32.5 10.4 53.5 0.6 13.9 54.9 179.5 12.8 9.6 57.0 0.0 71.1 13.1 0.2 1.9 47.4 1.4 86.5 235.3 275.9 0.0 0.4 3.2 22.3 240.8 243.9 11.7 148.2 2.5 0.3 157.8 2.2 16.5 0.0 3.3 0.2 2.0 5.0 38.5 4.4 109.0 5.8 53.4 7.5 0.6 52.2 20.6 2.0 19.9 20.6 0.0 41.8 3.6 26.3 0.0 6.3 3.3 3.3 210.4 91.0 452.4 0.4 1.0 22.8 41.6 54.9 10.1 8.8 0.0 16.8 ADAMTS17 "FLJ16363, FLJ32769" ENSG00000140470 "ADAM metallopeptidase with thrombospondin type 1 motif 17" Q8TE56 15 99971437-100342005 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Deafness, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 10.7" "Group enriched" "Detected in many" 8 "Astrocytes: 116.9;Early spermatids: 108.4;Inhibitory neurons: 275.7;Late spermatids: 91.0;Oligodendrocyte precursor cells: 337.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HEK 293: 6.4;JURKAT: 19.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA062487 Approved Nucleoplasm "Secreted to extracellular matrix" NA NA "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA062487: AB_2684780" "unprognostic (7.73e-2)" "unprognostic (2.38e-2)" "unprognostic (1.79e-2)" "unprognostic (9.03e-3)" "unprognostic (2.56e-1)" "unprognostic (9.90e-3)" "unprognostic (5.78e-2)" "unprognostic (1.18e-3)" "unprognostic (5.03e-3)" "unprognostic (4.70e-2)" "unprognostic (2.93e-1)" "unprognostic (1.27e-1)" "unprognostic (3.35e-2)" "unprognostic (8.48e-2)" "unprognostic (1.21e-1)" "unprognostic (7.43e-3)" "unprognostic (6.43e-2)" 0.8 1.2 1.6 0.5 1.1 0.6 0.6 0.3 2.7 1.4 6.0 0.9 0.6 1.2 0.6 2.1 1.8 0.3 1.3 1.3 0.6 1.1 7.5 1.5 0.5 1.2 0.7 1.7 5.0 0.2 1.2 0.5 0.8 1.0 0.4 0.7 2.6 0.5 5.6 2.2 1.2 0.5 0.7 0.9 1.0 2.7 1.0 10.7 0.7 0.1 0.5 1.6 1.4 1.1 0.0 0.0 0.0 0.3 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 1.2 0.3 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 19.5 0.0 0.0 0.0 0.7 2.0 0.5 0.2 0.9 1.0 0.0 0.3 2.3 0.0 0.2 1.7 0.2 0.2 2.2 2.7 0.4 0.0 0.2 0.3 0.0 0.6 0.6 0.0 0.2 0.0 0.0 0.0 0.4 2.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.1 0.3 2.7 1.3 0.6 1.2 0.7 0.8 0.7 1.0 1.1 0.7 0.0 0.0 116.9 0.3 1.0 0.9 0.1 3.4 0.8 1.5 1.3 4.3 1.5 0.9 0.0 0.0 0.1 2.6 0.4 1.9 0.1 108.4 1.2 2.8 0.9 0.0 0.0 8.2 0.9 0.0 1.6 5.1 1.8 0.0 0.1 0.4 4.4 8.2 21.9 275.7 0.7 0.0 0.6 0.3 91.0 2.1 0.4 0.0 22.5 0.0 1.3 1.0 337.3 9.5 0.3 0.2 0.0 0.8 1.6 0.5 0.1 0.0 0.7 0.0 3.2 0.9 1.7 1.9 2.1 0.6 0.1 3.7 2.5 0.4 0.9 ADAMTS6 ADAM-TS6 ENSG00000049192 "ADAM metallopeptidase with thrombospondin type 1 motif 6" Q9UKP5 5 65148738-65481920 "Cancer-related genes, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 1.9" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 34.6;Inhibitory neurons: 63.6;Microglial cells: 31.9;Oligodendrocyte precursor cells: 139.7" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "memory B-cell: 2.1;naive B-cell: 1.3" "Lineage enhanced" "Detected in single" "B-cells: 2.1" "Cell line enhanced" "Detected in many" "BJ: 12.6;HBF TERT88: 13.4;hTEC/SVTERT24-B: 12.6;hTERT-HME1: 14.9;TIME: 14.5;U-2197: 16.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA043441 Enhanced "Secreted to extracellular matrix" NA Yes "Cluster 37: B-cells - Transcription" "Cluster 28: Placenta - Pregnancy" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA043441: AB_2678484" "unprognostic (1.53e-1)" "unprognostic (1.40e-1)" "unprognostic (2.70e-3)" "unprognostic (4.33e-2)" "unprognostic (1.03e-2)" "unprognostic (2.39e-2)" "unprognostic (8.24e-2)" "unprognostic (1.65e-2)" "unprognostic (4.77e-2)" "unprognostic (8.04e-2)" "unprognostic (1.56e-1)" "unprognostic (2.13e-1)" "unprognostic (1.13e-6)" "unprognostic (3.23e-5)" "unprognostic (2.09e-1)" "unprognostic (3.02e-4)" "unprognostic (4.18e-3)" 0.5 0.1 0.2 0.6 0.2 0.0 0.3 0.2 0.3 0.3 0.5 0.3 0.1 1.1 0.7 0.2 0.6 1.4 0.3 0.2 0.6 0.2 0.0 0.5 0.4 0.3 0.4 0.3 0.0 0.0 0.1 1.9 0.3 0.2 0.2 0.2 0.1 0.2 0.0 0.1 0.6 0.6 0.3 0.7 0.3 0.5 0.3 0.2 0.1 0.1 0.3 0.7 0.3 0.2 2.7 0.0 0.6 0.6 0.0 2.0 0.0 12.6 7.4 7.7 9.0 0.0 0.3 0.0 0.1 4.8 5.3 0.5 0.1 2.4 13.4 2.0 0.0 0.2 5.1 0.3 0.4 0.0 0.7 0.9 0.0 12.6 14.9 3.7 6.9 1.3 0.0 0.0 4.8 0.0 0.7 0.0 0.1 0.3 0.1 0.4 2.6 0.0 0.0 0.0 0.3 0.5 0.2 0.0 0.0 1.6 0.0 0.1 14.5 3.0 4.5 16.2 10.2 0.1 0.0 0.0 3.4 0.7 0.0 0.0 0.0 0.0 0.5 0.0 0.4 2.1 0.1 0.2 0.0 1.3 0.5 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.2 0.2 0.3 0.2 0.6 0.3 0.4 0.3 0.3 0.3 0.2 11.3 0.0 0.0 4.9 16.1 0.3 0.0 0.6 0.6 13.9 0.3 0.5 1.8 1.5 0.1 3.7 0.0 34.6 3.2 0.2 0.0 1.4 15.2 8.5 7.4 13.3 0.0 0.0 16.7 0.0 4.7 5.5 0.0 25.7 1.3 18.7 8.9 0.3 2.4 0.0 63.6 0.5 2.0 0.3 1.0 8.0 12.2 3.2 0.0 31.9 0.3 17.4 1.0 139.7 2.1 2.6 0.0 18.0 2.5 0.1 0.1 1.0 0.1 1.1 6.6 5.1 10.5 6.1 8.9 0.3 0.0 14.2 5.1 2.2 0.6 0.0 ADAP2 CENTA2 ENSG00000184060 "ArfGAP with dual PH domains 2" Q9NPF8 17 30906344-30959322 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 86.2;Hofbauer cells: 195.8;Kupffer cells: 186.8;Macrophages: 97.2;monocytes: 88.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "classical monocyte: 22.4;intermediate monocyte: 34.3;myeloid DC: 12.6;non-classical monocyte: 43.5" "Group enriched" "Detected in many" 9 "dendritic cells: 12.6;monocytes: 43.5" "Cell line enhanced" "Detected in some" "EFO-21: 7.0;HAP1: 17.6;HEK 293: 11.0;RPMI-8226: 22.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" "unprognostic (4.00e-2)" "unprognostic (1.68e-2)" "prognostic unfavorable (5.62e-4)" "unprognostic (2.25e-1)" "unprognostic (9.26e-2)" "prognostic favorable (3.97e-4)" "prognostic unfavorable (3.12e-4)" "unprognostic (2.38e-1)" "unprognostic (3.40e-1)" "unprognostic (1.54e-1)" "unprognostic (2.51e-1)" "unprognostic (9.49e-2)" "prognostic unfavorable (2.36e-6)" "unprognostic (1.42e-1)" "unprognostic (1.42e-2)" "unprognostic (1.17e-2)" "unprognostic (1.14e-2)" 11.3 8.9 6.6 15.3 7.6 3.9 4.6 6.7 8.5 2.9 9.1 6.5 5.7 3.2 2.9 3.1 3.3 9.2 4.4 6.2 8.0 5.1 11.0 9.8 9.8 12.1 9.6 1.9 3.1 9.1 1.9 19.7 10.4 2.4 8.0 1.3 3.1 3.1 1.8 6.7 5.6 9.8 8.6 22.5 4.3 2.0 14.7 4.6 3.2 6.4 6.7 9.0 2.2 12.9 0.1 1.7 0.2 0.4 0.4 0.5 4.5 0.1 0.0 0.3 0.1 0.7 0.7 1.0 7.0 0.1 0.2 0.1 17.6 0.2 0.3 0.4 11.0 0.0 1.0 2.0 2.9 0.4 1.9 1.1 4.4 0.9 0.6 0.2 0.0 0.0 0.2 1.8 0.6 3.6 0.1 0.3 0.1 0.4 0.1 0.3 0.0 22.9 2.4 2.3 0.3 0.1 0.3 0.2 0.1 1.5 3.8 2.9 0.0 0.4 1.1 0.8 0.1 0.8 0.5 1.0 0.4 0.4 0.0 0.2 22.4 0.0 0.0 34.3 0.0 3.0 0.1 0.1 12.6 2.1 0.1 0.1 1.7 0.0 43.5 0.4 0.4 6.6 6.6 7.6 6.7 8.5 6.2 8.0 12.1 9.6 10.4 8.6 14.7 12.9 5.4 3.2 5.2 2.6 8.6 2.0 0.5 0.5 2.2 0.8 0.7 2.4 1.5 1.5 0.9 0.0 2.1 23.5 0.2 3.1 0.0 0.3 0.6 1.7 0.6 7.8 0.0 0.4 1.1 1.4 86.2 1.9 0.0 1.2 3.8 0.4 4.6 1.6 195.8 0.0 1.4 0.6 0.0 186.8 13.1 0.5 0.9 97.2 0.0 40.3 88.2 0.6 2.1 2.0 1.3 0.9 0.9 0.4 2.6 0.9 0.3 8.3 2.2 2.8 39.5 1.2 26.5 0.9 0.9 1.0 6.5 26.4 1.6 0.2 0.3 0.6 ADCY9 AC9 ENSG00000162104 "Adenylate cyclase 9" O60503 16 3953387-4116442 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 45.4;skeletal muscle: 52.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 95.3;Inhibitory neurons: 72.7;Oligodendrocyte precursor cells: 42.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 40.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041328, HPA044225" Approved Approved Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 20: HeLa - Mitochondria" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA041328: AB_2677414, HPA044225: AB_2678863" "unprognostic (1.78e-1)" "unprognostic (5.54e-2)" "unprognostic (2.57e-1)" "prognostic unfavorable (2.55e-5)" "unprognostic (6.62e-2)" "unprognostic (1.30e-2)" "unprognostic (2.52e-1)" "unprognostic (3.61e-2)" "unprognostic (6.93e-2)" "unprognostic (4.76e-3)" "unprognostic (5.40e-2)" "unprognostic (1.37e-1)" "prognostic favorable (5.24e-8)" "unprognostic (1.19e-1)" "unprognostic (1.66e-1)" "unprognostic (1.44e-1)" "unprognostic (1.55e-2)" 6.9 5.6 5.1 4.4 7.6 1.5 6.1 3.2 7.5 8.2 45.4 8.2 8.2 8.0 2.4 8.4 9.2 6.9 14.9 10.7 0.0 9.4 11.9 14.0 1.9 3.0 0.6 11.2 15.8 9.1 5.1 9.9 0.9 4.4 6.8 2.9 11.9 5.8 52.9 5.9 9.6 7.9 0.1 4.4 6.4 4.0 1.3 2.1 18.8 28.6 2.6 9.7 6.1 5.2 8.5 12.9 3.8 7.0 13.3 16.0 5.6 14.5 15.1 8.0 6.3 10.6 7.2 0.0 21.8 40.1 4.8 8.0 14.9 9.1 5.4 10.4 14.3 0.3 29.4 20.3 14.2 1.1 6.4 17.1 13.6 9.3 4.9 6.6 5.4 2.7 4.7 0.0 8.3 15.3 0.1 4.4 6.9 3.6 6.9 13.3 18.0 0.4 2.9 2.3 8.7 3.8 11.3 13.2 9.6 4.2 33.5 15.0 4.9 15.8 4.3 15.6 6.4 3.2 2.1 1.7 3.4 4.4 6.3 0.8 0.3 0.2 0.4 0.3 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.1 0.3 0.0 0.2 0.0 0.3 5.1 7.6 3.2 7.5 10.7 0.0 3.0 0.6 0.9 0.1 1.3 5.2 7.0 12.8 12.8 33.3 1.0 6.4 1.1 3.9 5.2 10.6 4.2 3.7 17.3 22.8 7.1 12.9 12.5 1.8 5.8 19.5 0.0 4.5 0.8 6.1 10.5 6.3 1.2 0.4 95.3 5.3 1.8 8.1 1.5 5.7 0.0 15.3 8.2 19.9 1.5 1.7 72.7 7.6 2.0 4.7 2.0 2.2 8.4 3.3 7.2 31.9 2.6 5.5 4.1 42.3 12.5 3.5 4.3 7.5 2.5 1.1 15.0 5.6 9.5 14.9 0.0 9.4 12.5 1.1 5.0 0.9 3.8 1.0 3.4 4.8 7.2 1.3 ADGRD2 "GPR144, PGR24" ENSG00000180264 "Adhesion G protein-coupled receptor D2" Q7Z7M1 9 124451425-124478589 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 1.3;pituitary gland: 1.6;seminal vesicle: 1.2" "Group enriched" "Detected in some" 14 "Early spermatids: 34.0;Late spermatids: 88.4" "Not detected" "Not detected" "Region enhanced" "Detected in single" "spinal cord: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "midbrain: 1.1" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (7.39e-4)" "unprognostic (1.34e-2)" "unprognostic (4.21e-2)" "unprognostic (8.01e-3)" "unprognostic (6.29e-2)" "unprognostic (3.23e-6)" "unprognostic (1.15e-1)" "unprognostic (3.15e-1)" "unprognostic (5.82e-2)" "unprognostic (4.22e-2)" "unprognostic (3.63e-2)" "unprognostic (2.25e-1)" "unprognostic (3.00e-1)" "unprognostic (1.65e-1)" "unprognostic (1.41e-1)" 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.3 0.0 0.0 0.0 1.6 0.0 0.3 0.1 0.0 0.0 0.0 1.2 0.0 0.4 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.3 0.3 1.3 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 3.1 0.0 0.0 0.0 0.3 4.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 88.4 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 1.7 0.0 0.0 0.0 0.0 0.0 1.7 0.2 0.7 1.0 0.0 0.0 0.0 0.0 0.6 0.0 1.4 ADGRF1 "GPR110, hGPCR36, PGR19" ENSG00000153292 "Adhesion G protein-coupled receptor F1" Q5T601 6 46997708-47042350 "G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 17.5;kidney: 20.3;urinary bladder: 42.6" "Group enriched" "Detected in some" 4 "Collecting duct cells: 108.5;Pancreatic endocrine cells: 98.9;Urothelial cells: 363.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 31.2;CAPAN-2: 113.3;HaCaT: 25.3;PC-3: 36.6;RPTEC TERT1: 50.9;RT4: 132.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA038438 Approved "Secreted - unknown location" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "HPA038438: AB_10672645" "unprognostic (4.83e-4)" "unprognostic (1.38e-1)" "unprognostic (1.64e-1)" "unprognostic (6.71e-3)" "unprognostic (1.95e-3)" "unprognostic (3.02e-3)" "unprognostic (7.76e-2)" "unprognostic (2.63e-2)" "unprognostic (2.90e-1)" "unprognostic (4.20e-2)" "unprognostic (3.64e-3)" "unprognostic (1.99e-1)" "prognostic favorable (1.35e-5)" "unprognostic (7.41e-2)" "unprognostic (8.39e-2)" "unprognostic (1.76e-1)" "unprognostic (1.08e-2)" 0.1 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 3.4 0.0 0.3 0.0 0.2 0.1 17.5 0.8 6.1 0.0 0.0 0.0 20.3 0.0 3.6 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 3.0 0.1 0.0 3.2 1.7 0.0 0.0 3.2 0.0 0.0 0.0 1.4 0.6 0.0 0.1 6.2 0.0 5.9 42.6 6.4 0.0 31.2 0.1 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 113.3 0.0 2.0 0.0 0.0 25.3 0.0 7.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 20.5 36.6 0.0 0.0 0.0 50.9 132.6 0.0 0.0 0.0 4.2 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 21.8 0.0 0.1 0.0 25.4 0.0 0.6 0.0 5.5 1.9 0.7 12.8 13.6 108.5 0.0 0.0 0.0 1.5 23.5 30.8 0.0 7.0 5.0 0.7 0.0 0.0 0.1 18.9 0.1 0.8 3.6 46.9 1.3 0.0 0.0 0.0 0.1 0.0 0.1 0.6 0.0 0.0 0.0 0.2 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 98.9 0.0 0.0 0.0 39.1 1.2 0.7 14.6 0.0 0.0 0.2 1.1 0.0 0.2 2.6 0.0 0.1 1.0 0.1 0.2 363.7 ADGRF5 "DKFZp564O1923, GPR116, KIAA0758" ENSG00000069122 "Adhesion G protein-coupled receptor F5" Q8IZF2 6 46852522-46954943 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 104.5" "Cell type enhanced" "Detected in many" "Adipocytes: 428.1;Alveolar cells type 1: 291.7;Alveolar cells type 2: 539.9;Endothelial cells: 222.6;Hepatic stellate cells: 251.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "HUVEC TERT2: 25.0;TIME: 74.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 55000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (8.45e-2)" "unprognostic (3.00e-3)" "unprognostic (1.13e-1)" "unprognostic (3.26e-1)" "unprognostic (6.51e-2)" "unprognostic (1.89e-2)" "unprognostic (5.76e-2)" "unprognostic (9.00e-3)" "unprognostic (7.80e-2)" "unprognostic (3.32e-1)" "unprognostic (1.42e-1)" "unprognostic (4.56e-2)" "prognostic favorable (8.84e-5)" "unprognostic (1.43e-2)" "unprognostic (5.91e-2)" "unprognostic (2.82e-2)" "unprognostic (3.78e-2)" 69.8 22.8 15.1 6.9 15.0 0.0 46.0 15.0 18.0 10.4 8.6 9.9 5.7 16.0 7.7 7.0 15.0 16.9 51.6 12.8 15.1 58.9 13.0 104.5 8.5 16.6 15.6 6.5 6.4 13.2 6.7 50.6 18.2 8.9 5.7 1.8 5.9 9.2 30.4 7.7 8.5 21.8 13.8 40.5 8.4 3.1 21.6 3.7 32.2 70.2 3.2 11.4 10.0 15.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 74.1 0.0 0.2 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.1 15.0 15.0 18.0 12.8 15.1 16.6 15.6 18.2 13.8 21.6 15.3 428.1 291.7 539.9 2.0 2.9 0.0 0.2 0.0 2.2 0.0 1.5 2.9 16.2 8.6 89.7 1.8 0.0 0.2 1.1 0.6 11.7 0.2 10.6 0.8 1.2 222.6 0.0 0.0 8.4 0.0 1.1 9.0 2.6 0.4 12.6 0.0 251.3 4.0 0.2 0.0 1.0 0.5 0.0 13.7 0.0 4.8 3.1 2.7 0.0 104.0 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 1.2 0.6 0.5 0.2 48.1 0.7 98.6 9.6 80.1 0.2 0.9 0.6 0.0 0.3 1.8 15.5 0.1 0.8 ADGRG6 "FLJ14937, GPR126" ENSG00000112414 "Adhesion G protein-coupled receptor G6" Q86SQ4 6 142301854-142446266 "Disease related genes, G-protein coupled receptors, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 71.9;placenta: 47.4" "Cell type enhanced" "Detected in many" "Endothelial cells: 41.7;Hepatocytes: 143.8;Kupffer cells: 40.5;Pancreatic endocrine cells: 37.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 88.6;Hep G2: 84.8;hTERT-HME1: 81.5;HUVEC TERT2: 161.4;MCF7: 155.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA017346 Approved NA NA 110000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 15: Hepatocytes - Hemostasis" "HPA017346: AB_1849260" "unprognostic (1.04e-2)" "unprognostic (2.72e-2)" "unprognostic (7.37e-2)" "unprognostic (3.00e-2)" "unprognostic (8.64e-4)" "unprognostic (1.67e-1)" "unprognostic (2.98e-1)" "prognostic unfavorable (8.78e-4)" "unprognostic (1.80e-1)" "unprognostic (1.26e-1)" "prognostic unfavorable (2.78e-5)" "unprognostic (4.46e-1)" "unprognostic (6.49e-2)" "unprognostic (2.15e-1)" "unprognostic (1.36e-2)" "unprognostic (2.97e-2)" "unprognostic (4.59e-2)" 5.8 2.8 2.6 4.1 2.3 0.4 5.2 1.6 1.9 3.0 1.9 6.2 17.5 1.1 1.3 11.6 5.2 8.3 4.0 1.8 1.7 7.2 71.9 15.2 1.7 2.4 2.9 1.4 3.2 1.3 0.3 47.4 2.2 3.2 6.4 0.1 9.0 6.5 0.5 14.5 10.2 2.2 2.5 7.5 12.3 2.1 4.6 4.6 1.6 1.2 4.0 15.1 5.6 1.9 17.0 88.6 1.9 9.4 0.5 0.0 0.2 23.1 4.3 17.2 10.7 71.3 51.0 0.0 20.3 13.4 4.9 41.3 2.6 22.1 28.3 0.0 6.8 3.6 14.5 84.8 16.7 14.6 0.0 0.1 34.9 0.4 81.5 10.0 161.4 0.4 0.6 0.1 6.9 155.6 0.3 0.0 0.7 6.2 20.0 0.0 7.7 17.7 9.0 37.9 0.1 0.1 6.8 30.8 14.5 14.1 16.7 0.3 5.6 0.1 7.6 7.7 11.5 0.0 0.1 0.0 0.1 0.1 76.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 2.3 1.6 1.9 1.8 1.7 2.4 2.9 2.2 2.5 4.6 1.9 5.1 6.4 5.9 0.0 0.3 0.0 21.9 0.0 18.8 0.0 5.3 2.7 1.9 24.3 8.1 9.2 0.0 5.3 0.0 0.6 0.0 13.2 0.1 0.1 0.5 41.7 0.0 17.0 1.6 5.4 33.5 14.5 32.1 0.5 0.0 0.0 27.1 143.8 2.2 0.0 12.7 3.5 0.0 40.5 0.0 0.6 0.6 8.1 0.0 15.0 0.9 0.0 0.0 0.5 0.3 37.9 8.8 0.4 0.1 18.7 9.5 11.8 2.9 0.0 6.6 0.4 1.3 2.6 5.3 30.2 0.0 13.5 1.6 0.0 1.7 25.0 ADH1B ADH2 ENSG00000196616 "Alcohol dehydrogenase 1B (class I), beta polypeptide" P00325 4 99304971-99352760 "Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 1501.5;liver: 5858.7" "Cell type enriched" "Detected in many" 6 "Hepatocytes: 4153.7" "Cancer enriched" "Detected in many" 31 "liver cancer: 223.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "ASC diff: 6574.3" "HPA047814, HPA060902" Supported Approved "Plasma membrane,Cytosol" NA NA 39000000 "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "Plasma membrane, Cytosol" "HPA047814: AB_2680163, HPA060902: AB_2684384" "unprognostic (5.13e-2)" "unprognostic (9.80e-3)" "unprognostic (6.59e-2)" "unprognostic (5.56e-2)" "unprognostic (9.49e-2)" "unprognostic (5.53e-2)" "unprognostic (1.54e-3)" "unprognostic (1.04e-2)" "unprognostic (6.51e-2)" "unprognostic (2.73e-2)" "unprognostic (7.47e-3)" "unprognostic (7.79e-2)" "prognostic unfavorable (7.87e-4)" "unprognostic (4.60e-3)" "unprognostic (2.33e-1)" "unprognostic (2.58e-1)" "unprognostic (1.60e-2)" 1501.5 140.2 2.2 36.4 3.4 0.1 924.6 1.9 9.0 41.0 13.5 202.2 38.5 161.4 74.8 105.8 385.0 145.1 215.3 2.0 1.9 66.7 5858.7 373.2 25.8 4.7 2.2 117.7 49.1 7.8 24.2 6.8 3.2 26.7 114.7 0.1 67.9 26.7 66.6 159.2 237.1 73.4 4.4 72.7 141.1 2.8 2.2 19.8 94.5 228.2 16.0 287.9 118.7 2.4 0.0 0.0 0.0 0.0 6574.3 956.7 0.2 0.0 2.0 0.0 0.0 0.0 0.0 0.7 0.1 1.1 0.0 0.0 0.5 1.4 0.0 0.1 0.0 1.1 0.1 0.0 26.9 3.0 0.0 216.8 0.1 0.0 0.8 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.1 0.5 0.1 0.0 0.0 0.1 3.2 0.1 0.0 0.0 0.1 0.2 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.5 0.2 0.2 0.3 1.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 3.4 1.9 9.0 2.0 1.9 4.7 2.2 3.2 4.4 2.2 2.4 29.0 0.0 3.4 0.0 8.1 22.3 0.5 0.1 6.8 0.1 1.1 2.5 12.2 110.1 2.3 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.6 0.1 0.9 14.7 0.0 115.0 0.0 0.0 0.1 633.1 11.2 0.0 1.3 0.0 96.8 4153.7 0.1 0.0 0.0 0.0 0.0 98.8 25.4 0.6 55.3 3.5 28.4 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 7.1 0.7 0.0 0.1 0.2 0.1 6.6 15.0 47.9 0.0 0.1 10.4 13.1 0.1 8.9 0.1 0.0 0.2 ADIPOR1 "ACDCR1, PAQR1" ENSG00000159346 "Adiponectin receptor 1" Q96A54 1 202940826-202958572 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 329.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 28: BEWO - Transcription regulation" "Cluster 6: Erythroid cells - Oxygen transport" "unprognostic (1.67e-1)" "unprognostic (1.58e-1)" "unprognostic (3.81e-2)" "unprognostic (2.74e-1)" "unprognostic (1.59e-1)" "unprognostic (1.22e-1)" "unprognostic (9.95e-2)" "unprognostic (4.32e-2)" "unprognostic (1.47e-1)" "prognostic favorable (5.27e-4)" "prognostic unfavorable (5.50e-4)" "unprognostic (1.13e-1)" "unprognostic (1.79e-3)" "unprognostic (5.90e-2)" "unprognostic (1.75e-1)" "unprognostic (2.84e-1)" "unprognostic (8.63e-2)" 59.8 58.5 56.1 49.1 60.1 215.2 63.6 58.7 64.2 55.4 82.9 55.6 46.5 40.9 91.4 110.9 68.6 48.2 92.6 56.8 57.7 70.4 106.2 80.5 48.0 61.2 58.6 47.7 91.7 107.1 45.5 100.0 60.2 53.7 59.8 135.6 106.6 47.4 136.5 110.8 47.4 50.9 60.1 65.8 63.3 48.7 58.7 50.2 56.6 140.2 77.9 70.9 69.2 65.2 97.0 87.2 53.4 59.9 111.4 85.4 276.8 103.4 123.9 108.8 99.4 88.7 114.7 63.5 75.3 120.6 86.3 118.0 81.3 145.5 96.5 118.5 93.5 48.6 104.3 72.6 109.7 101.6 71.6 101.7 235.0 115.9 118.3 108.4 108.8 111.7 128.1 133.5 111.2 105.6 85.3 77.4 119.7 87.1 103.1 66.7 128.7 125.7 106.5 111.0 89.2 90.8 109.6 166.5 135.5 143.6 121.1 99.4 95.7 78.9 62.2 39.4 117.3 137.8 197.4 71.4 113.5 58.9 94.5 362.2 361.8 455.4 136.0 253.6 143.8 157.9 143.4 134.1 209.8 165.2 141.5 124.3 825.9 126.0 259.6 146.1 179.5 557.4 56.1 60.1 58.7 64.2 56.8 57.7 61.2 58.6 60.2 60.1 58.7 65.2 40.7 35.3 52.5 6.8 46.8 235.0 95.2 109.8 75.7 24.8 81.9 54.2 59.7 32.9 79.3 53.3 29.2 112.7 42.8 49.3 68.4 73.8 68.2 58.8 24.5 53.4 49.1 329.0 13.7 86.3 172.4 40.9 37.2 54.3 37.3 18.8 58.5 60.8 104.2 11.8 15.1 49.1 85.5 148.5 89.7 62.5 28.6 107.6 85.4 15.9 85.0 38.0 42.2 9.5 20.0 120.0 43.5 24.5 116.0 133.1 67.3 65.9 82.5 54.9 39.5 29.2 61.7 26.4 27.2 79.3 228.9 202.8 47.1 29.2 41.7 206.6 ADK AK ENSG00000156110 "Adenosine kinase" P55263 10 74151202-74709963 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Purine salvage" "Kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 151.2" "Cell type enhanced" "Detected in all" "Excitatory neurons: 245.3;Inhibitory neurons: 287.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032876, HPA038391, HPA038409, HPA075222" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 920000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB032876: AB_2242229, HPA038391: AB_2675990, HPA038409: AB_10675798, HPA075222: " "unprognostic (1.55e-3)" "unprognostic (1.09e-1)" "unprognostic (1.88e-1)" "unprognostic (2.62e-2)" "unprognostic (2.52e-2)" "prognostic unfavorable (1.93e-4)" "prognostic favorable (9.91e-4)" "unprognostic (2.64e-1)" "unprognostic (2.88e-1)" "unprognostic (1.55e-1)" "unprognostic (8.15e-3)" "unprognostic (2.51e-1)" "unprognostic (1.89e-3)" "unprognostic (2.03e-1)" "unprognostic (2.88e-2)" "unprognostic (4.97e-3)" "unprognostic (2.95e-2)" 23.9 15.5 13.0 16.9 18.7 28.6 27.4 13.5 17.7 17.5 11.6 17.9 16.9 10.8 16.5 47.3 16.5 11.4 27.2 13.9 15.2 35.8 151.2 24.4 22.8 14.0 15.0 8.3 18.8 44.2 14.9 26.6 16.5 14.9 19.5 16.1 20.0 16.0 41.5 33.9 12.4 14.8 14.2 15.0 12.1 15.5 14.1 27.0 38.2 47.1 34.5 24.5 24.7 15.8 177.3 37.4 37.2 50.5 37.1 54.7 88.2 140.8 105.4 103.8 114.5 114.0 172.6 86.3 34.2 57.7 51.3 151.1 44.1 150.1 167.0 59.1 51.3 55.6 59.8 122.8 41.7 87.6 22.5 51.1 95.5 77.4 191.7 79.0 91.2 38.7 41.8 28.4 78.8 101.7 102.5 129.0 9.9 80.0 276.3 100.6 63.7 69.4 117.1 92.7 29.5 33.8 63.6 239.7 49.5 34.7 159.7 69.3 82.8 34.3 67.0 93.2 123.0 40.5 48.3 98.1 65.0 127.6 22.1 2.3 34.2 4.1 12.9 65.5 29.9 103.7 28.2 24.1 83.1 155.0 21.3 19.2 11.1 20.7 80.4 57.6 55.7 36.3 13.0 18.7 13.5 17.7 13.9 15.2 14.0 15.0 16.5 14.2 14.1 15.8 9.8 83.3 75.8 136.5 84.2 94.2 73.5 102.0 105.9 16.3 26.2 26.0 67.8 38.6 72.4 31.3 56.3 136.7 25.9 11.0 92.0 83.2 80.7 40.6 18.8 14.9 10.8 27.7 245.3 67.5 139.5 27.0 23.0 55.6 21.5 9.7 17.2 130.1 39.3 11.8 287.7 12.1 44.7 25.2 50.0 26.9 16.8 33.7 48.0 198.6 44.1 14.1 11.3 140.8 165.4 62.7 10.4 12.0 39.1 92.1 5.0 64.5 33.5 25.0 6.6 20.4 26.0 17.4 14.3 96.7 97.0 107.3 32.7 17.0 20.5 66.3 ADM AM ENSG00000148926 Adrenomedullin P35318 11 10305073-10307397 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Hormone "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 340.2" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 590.8;Extravillous trophoblasts: 1217.1;Syncytiotrophoblasts: 1084.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 18 "neutrophil: 242.2" "Lineage enriched" "Detected in many" 18 "granulocytes: 242.2" "Cell line enhanced" "Detected in many" "ASC diff: 684.6;fHDF/TERT166: 357.4;HSkMC: 410.9;U-138 MG: 390.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB016075, HPA068955" Approved "Secreted to blood" NA NA 31000 340000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" "CAB016075: AB_628693, HPA068955: " "unprognostic (1.67e-1)" "unprognostic (2.89e-2)" "unprognostic (1.78e-1)" "unprognostic (5.22e-2)" "unprognostic (1.55e-2)" "unprognostic (5.27e-3)" "prognostic unfavorable (7.56e-4)" "unprognostic (1.78e-3)" "unprognostic (1.06e-1)" "unprognostic (2.83e-1)" "unprognostic (8.13e-3)" "unprognostic (3.12e-1)" "prognostic unfavorable (6.33e-4)" "unprognostic (9.70e-3)" "unprognostic (2.01e-1)" "unprognostic (2.02e-2)" "unprognostic (1.62e-2)" 340.2 29.9 12.9 32.2 18.3 43.9 195.9 28.1 15.2 162.1 17.9 60.6 8.0 20.3 3.1 84.6 71.0 30.0 153.3 10.6 15.5 123.8 90.5 157.6 17.1 19.7 18.0 33.1 24.6 23.5 43.3 102.8 16.5 26.8 11.4 16.7 52.7 1.6 79.3 169.8 49.5 7.6 16.8 34.5 55.5 4.9 21.6 4.1 52.7 14.3 3.5 85.1 224.3 18.6 35.4 29.2 33.8 9.8 684.6 306.7 51.8 263.6 263.9 260.5 175.7 142.4 43.9 0.1 11.7 357.4 136.9 51.0 9.5 40.6 191.9 0.7 13.9 1.1 16.1 18.0 88.0 1.6 1.1 410.9 34.7 30.8 44.6 89.9 60.4 0.5 0.4 0.7 64.3 1.2 0.2 10.6 65.7 8.4 13.6 1.0 1.1 54.5 16.7 48.6 1.1 3.2 101.0 23.7 0.6 36.4 31.4 0.3 17.9 390.0 5.5 233.2 37.9 2.7 29.5 10.5 112.0 0.2 117.0 0.0 7.0 0.0 0.0 7.7 0.0 0.3 0.0 0.0 2.4 0.0 0.0 0.1 242.2 0.0 13.6 0.0 0.3 1.9 12.9 18.3 28.1 15.2 10.6 15.5 19.7 18.0 16.5 16.8 21.6 18.6 347.7 9.6 12.3 17.0 14.2 192.1 590.8 194.4 182.1 2.7 28.0 46.9 104.6 18.6 136.2 3.7 8.4 134.6 9.1 266.7 15.6 135.7 0.5 80.8 58.1 99.1 67.5 4.0 0.4 30.5 1217.1 202.8 55.0 210.9 9.5 30.1 95.7 18.6 71.4 3.3 3.0 127.6 181.0 69.6 57.7 2.6 132.7 107.9 40.9 6.5 8.1 4.9 1.0 1.5 0.1 61.7 298.3 19.2 20.0 218.9 14.0 60.1 38.7 15.3 0.0 73.3 76.5 5.1 4.9 182.3 125.6 1084.8 14.7 8.1 55.5 224.5 ADPRS "ADPRHL2, ARH3, FLJ20446" ENSG00000116863 "ADP-ribosylserine hydrolase" Q9NX46 1 36088892-36093932 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" Hydrolase "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 6 "Cytotrophoblasts: 79.2;Extravillous trophoblasts: 40.7;Hofbauer cells: 51.6;Syncytiotrophoblasts: 70.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026641, HPA027104, HPA027141" Approved Enhanced Nucleoplasm "Intracellular and membrane" NA NA 54000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "HPA026641: , HPA027104: AB_10601330, HPA027141: AB_1844619" "unprognostic (3.22e-3)" "unprognostic (5.10e-2)" "unprognostic (2.95e-2)" "unprognostic (1.61e-2)" "unprognostic (5.98e-2)" "unprognostic (2.09e-1)" "prognostic unfavorable (2.10e-7)" "unprognostic (3.71e-2)" "unprognostic (2.63e-1)" "unprognostic (5.34e-2)" "unprognostic (3.17e-2)" "unprognostic (7.80e-2)" "prognostic unfavorable (3.71e-4)" "unprognostic (4.37e-2)" "unprognostic (9.31e-2)" "unprognostic (3.65e-2)" "unprognostic (4.74e-2)" 19.0 36.7 28.4 16.0 30.0 19.7 18.5 31.3 30.3 20.7 33.4 19.6 15.6 17.6 15.0 36.1 33.5 13.3 20.7 28.6 29.1 27.7 22.4 20.6 21.5 32.5 29.7 19.7 17.9 17.6 17.7 20.8 31.2 19.9 12.4 9.1 20.9 16.3 34.4 34.1 16.8 16.4 31.9 23.1 17.6 28.7 29.7 20.9 19.4 21.8 20.2 21.3 22.2 33.9 54.3 22.4 26.2 37.2 23.6 17.1 37.3 39.4 32.9 62.1 60.9 26.8 47.7 38.4 37.5 39.5 32.0 32.9 33.4 60.5 37.0 27.7 41.8 34.9 27.0 36.3 44.4 40.2 19.9 20.3 45.4 56.5 24.5 47.2 39.9 36.2 30.8 30.9 29.6 26.0 40.9 60.5 56.5 31.8 46.0 32.9 27.6 38.8 56.5 43.8 32.1 50.8 28.9 29.9 65.9 34.4 30.9 34.3 27.6 35.7 37.0 50.1 53.0 39.8 41.2 34.2 51.7 39.6 22.4 40.6 58.3 65.8 43.4 74.1 41.5 43.5 47.6 50.8 71.4 51.5 47.7 40.3 57.1 47.9 77.7 44.8 43.4 57.8 28.4 30.0 31.3 30.3 28.6 29.1 32.5 29.7 31.2 31.9 29.7 33.9 3.5 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.5 0.0 0.0 0.0 0.0 79.2 6.2 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 40.7 6.4 0.0 0.0 0.0 0.0 0.0 0.0 51.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 70.6 1.3 0.0 0.0 0.0 ADRM1 "ARM1, GP110, Rpn13" ENSG00000130706 "Adhesion regulating molecule 1" Q16186 20 62302093-62308862 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 369.5" "Cell type enhanced" "Detected in all" "Late spermatids: 1655.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "CACO-2: 727.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042266 Supported Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 28000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 39: CACO-2 - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Plasma membrane, Cytosol" "HPA042266: AB_10794044" "unprognostic (5.49e-2)" "unprognostic (5.14e-3)" "unprognostic (7.34e-2)" "unprognostic (6.16e-2)" "unprognostic (2.06e-2)" "unprognostic (1.06e-1)" "unprognostic (1.77e-3)" "unprognostic (2.14e-2)" "unprognostic (3.56e-2)" "unprognostic (2.13e-3)" "unprognostic (8.98e-2)" "unprognostic (3.50e-1)" "prognostic unfavorable (9.02e-6)" "unprognostic (4.15e-2)" "unprognostic (1.09e-1)" "unprognostic (3.22e-1)" "unprognostic (8.47e-2)" 76.9 92.7 44.9 53.4 45.6 78.0 68.3 48.7 63.7 57.8 38.1 78.7 52.0 80.6 14.6 99.0 58.4 33.5 109.0 44.0 48.4 65.1 119.5 67.3 54.2 52.0 45.7 44.5 83.2 23.5 52.6 39.6 51.0 59.5 16.1 11.9 61.3 35.1 369.5 93.9 63.4 23.3 44.4 83.2 68.6 128.5 47.3 38.9 51.7 66.9 29.7 73.0 64.4 46.4 219.9 241.8 66.8 142.6 62.5 45.8 178.1 138.9 95.4 260.1 104.0 727.1 227.8 117.4 250.3 82.1 148.3 243.6 84.3 209.9 79.8 136.7 170.1 284.4 177.4 392.0 105.6 149.3 261.1 57.0 126.3 170.9 67.7 43.4 101.4 113.0 211.4 125.6 61.7 296.1 187.5 290.8 225.1 106.6 354.0 149.2 115.5 186.7 71.3 163.9 118.5 146.5 151.5 241.7 174.0 44.9 168.1 163.3 149.4 258.5 274.4 252.4 289.1 261.5 223.4 158.6 272.6 148.7 192.3 195.4 208.7 233.5 200.4 262.1 179.9 260.2 180.8 192.9 219.2 265.2 132.4 151.4 200.2 184.8 227.8 205.6 265.8 260.8 44.9 45.6 48.7 63.7 44.0 48.4 52.0 45.7 51.0 44.4 47.3 46.4 91.4 35.3 25.2 7.5 91.3 148.2 115.6 275.4 98.4 34.7 62.0 62.0 19.4 52.9 119.3 66.2 18.8 230.4 83.3 156.4 115.4 186.9 359.1 61.7 43.9 105.6 57.8 74.3 5.2 211.3 173.6 73.3 51.0 56.9 42.5 55.8 87.1 101.7 150.2 33.7 4.9 87.1 156.6 77.6 154.2 1655.0 72.4 89.8 97.8 3.7 126.5 73.0 83.4 4.0 8.5 247.5 129.7 86.9 118.2 145.7 118.6 139.0 96.2 31.7 65.7 49.9 177.0 135.2 204.2 108.0 148.0 423.0 86.1 57.5 95.2 144.6 AFAP1 "AFAP, AFAP-110" ENSG00000196526 "Actin filament associated protein 1" Q8N556 4 7758714-7939926 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Early spermatids: 170.5;Extravillous trophoblasts: 116.3;Inhibitory neurons: 117.2;Late spermatids: 373.8;Oligodendrocyte precursor cells: 125.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 2.9" "Group enriched" "Detected in many" 5 "granulocytes: 2.9;T-cells: 1.2" "Cell line enhanced" "Detected in many" "TIME: 126.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015642, CAB024712" Enhanced Supported "Actin filaments,Focal adhesion sites,Cytosol" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Actin filaments, Cytosol" "Focal adhesion sites" "CAB024712: , HPA015642: AB_1844632" "unprognostic (1.12e-1)" "unprognostic (2.78e-2)" "unprognostic (3.97e-1)" "unprognostic (7.29e-2)" "unprognostic (2.02e-1)" "unprognostic (1.93e-1)" "unprognostic (3.30e-1)" "prognostic unfavorable (2.84e-4)" "unprognostic (2.00e-1)" "unprognostic (3.39e-2)" "unprognostic (3.40e-2)" "unprognostic (1.38e-1)" "prognostic unfavorable (8.18e-4)" "unprognostic (1.40e-2)" "unprognostic (1.56e-1)" "unprognostic (1.85e-1)" "unprognostic (2.44e-2)" 12.6 3.1 7.0 8.7 5.8 0.7 9.7 4.5 6.9 8.7 2.9 17.6 5.6 15.4 2.0 11.0 8.5 9.4 10.8 5.8 4.5 4.9 1.2 8.5 4.4 3.7 2.7 7.1 3.8 14.7 7.9 12.6 2.8 7.7 9.8 3.4 8.6 10.2 3.5 5.3 7.7 15.4 3.4 4.0 6.7 22.0 3.5 3.1 7.4 2.4 4.8 14.2 8.3 3.5 31.9 23.2 16.2 12.9 15.4 27.8 21.3 46.4 68.1 43.6 40.0 7.4 7.2 0.1 15.2 75.5 72.3 15.1 8.6 18.7 28.6 0.9 5.7 0.0 33.2 4.5 43.0 0.0 0.4 17.2 13.8 54.4 35.5 72.2 53.0 4.8 0.7 6.8 23.0 10.3 0.6 0.0 7.0 13.2 44.3 0.0 12.1 1.5 4.7 4.1 31.8 53.0 15.9 10.9 12.4 21.4 4.1 0.3 126.7 53.0 11.8 69.6 23.0 0.0 0.2 0.0 18.9 0.1 61.9 0.0 0.4 2.9 0.4 0.1 0.5 0.0 0.6 0.6 0.0 0.0 1.2 0.5 1.0 0.0 0.0 0.0 0.5 0.7 7.0 5.8 4.5 6.9 5.8 4.5 3.7 2.7 2.8 3.4 3.5 3.5 22.5 6.4 2.0 4.6 0.2 2.9 9.7 16.2 7.4 1.2 10.2 8.9 5.9 10.0 12.7 11.0 4.2 5.6 2.3 14.8 0.0 19.2 170.5 7.5 17.6 20.1 14.5 0.0 24.7 7.7 116.3 21.1 11.2 8.8 0.0 4.4 14.3 0.0 8.5 0.0 117.2 20.6 0.0 0.3 3.6 373.8 11.1 6.0 1.8 30.9 0.6 10.2 0.0 125.2 5.4 29.9 8.6 12.4 0.6 13.5 6.4 4.2 6.4 0.7 6.6 8.0 13.4 12.5 10.0 6.2 4.3 8.8 7.3 2.6 13.9 9.9 AGAP1 "CENTG2, GGAP1, KIAA1099" ENSG00000157985 "ArfGAP with GTPase domain, ankyrin repeat and PH domain 1" Q9UPQ3 2 235494043-236131800 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 53.9;retina: 54.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 304.0;Cone photoreceptor cells: 329.4;Excitatory neurons: 289.3;Oligodendrocyte precursor cells: 1438.1;Oligodendrocytes: 997.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "MAIT T-cell: 1.2" "Lineage enriched" "Detected in single" 13 "T-cells: 1.2" "Cell line enhanced" "Detected in many" "SCLC-21H: 78.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 68: Oligodendrocytes - Mixed function" "unprognostic (1.69e-1)" "unprognostic (2.32e-2)" "unprognostic (3.42e-1)" "unprognostic (5.43e-2)" "unprognostic (1.19e-1)" "unprognostic (4.80e-2)" "prognostic unfavorable (2.60e-5)" "unprognostic (1.36e-1)" "unprognostic (6.91e-2)" "prognostic unfavorable (9.75e-4)" "unprognostic (1.46e-1)" "unprognostic (2.10e-1)" "prognostic favorable (6.52e-5)" "unprognostic (5.56e-2)" "unprognostic (2.44e-2)" "unprognostic (6.32e-2)" "unprognostic (1.32e-2)" 5.3 4.7 30.7 3.4 34.4 1.9 8.3 7.6 29.6 5.7 0.0 12.5 7.0 5.2 8.9 6.6 6.7 5.6 5.9 34.0 33.0 7.7 2.6 5.6 1.7 44.6 24.1 5.5 6.5 8.9 7.1 6.9 48.2 4.8 11.2 54.7 4.2 5.0 8.4 3.7 8.6 10.5 10.9 1.9 6.7 6.6 30.5 1.5 9.1 9.2 1.9 6.2 3.4 53.9 17.3 13.6 20.9 9.8 15.1 9.7 13.1 8.6 9.1 9.9 7.5 14.0 31.3 0.1 3.6 14.9 37.2 4.3 15.8 20.4 12.3 0.3 8.1 26.4 12.5 10.5 6.0 0.1 17.5 14.1 19.3 20.4 15.9 7.1 6.8 6.1 13.8 1.0 12.6 22.2 0.5 3.0 9.1 14.9 6.2 3.6 10.6 16.8 10.8 20.4 78.9 19.9 7.3 17.1 9.5 11.4 9.8 4.1 6.8 11.8 12.0 9.8 11.7 5.4 0.1 0.8 18.4 0.2 12.7 0.0 0.0 0.0 0.6 0.0 1.2 0.0 0.1 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 30.7 34.4 7.6 29.6 34.0 33.0 44.6 24.1 48.2 10.9 30.5 53.9 16.0 6.4 15.5 100.6 0.2 4.1 3.7 6.2 5.2 304.0 19.4 11.7 22.9 2.8 8.7 11.0 329.4 9.7 5.5 23.3 3.9 21.4 9.4 24.0 12.0 13.3 16.3 0.4 289.3 15.0 1.5 19.5 4.6 15.8 20.8 12.7 7.9 6.3 1.4 119.5 219.0 17.8 12.2 0.6 3.8 2.9 5.0 2.1 1.8 139.6 1.6 33.3 9.2 1438.1 997.9 19.1 20.7 13.5 0.8 4.9 21.1 14.0 14.4 142.0 26.3 20.4 22.5 4.8 20.7 7.1 4.3 6.6 3.0 7.0 21.8 4.9 AGFG1 "HRB, RAB, RIP" ENSG00000173744 "ArfGAP with FG repeats 1" P52594 2 227472152-227561217 "Predicted intracellular proteins" "Differentiation, mRNA transport, Spermatogenesis, Transport" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 333.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008741 Approved Supported Vesicles NA NA 120000 "Cluster 7: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 28: BEWO - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "HPA008741: AB_1850752" "unprognostic (5.76e-2)" "prognostic unfavorable (7.13e-4)" "unprognostic (8.73e-3)" "unprognostic (6.31e-3)" "prognostic favorable (6.10e-4)" "unprognostic (9.30e-3)" "prognostic unfavorable (7.31e-6)" "prognostic unfavorable (1.85e-4)" "unprognostic (1.30e-1)" "prognostic unfavorable (3.43e-5)" "unprognostic (2.03e-2)" "unprognostic (5.78e-2)" "prognostic unfavorable (6.92e-4)" "unprognostic (1.25e-1)" "unprognostic (2.37e-1)" "unprognostic (1.98e-1)" "unprognostic (4.24e-3)" 69.4 39.4 30.4 48.4 31.6 155.5 51.1 29.3 36.0 25.3 23.8 32.2 43.4 25.7 20.1 47.2 27.3 38.9 36.2 32.4 27.0 36.9 36.2 54.6 47.1 34.6 29.0 26.1 35.0 41.6 17.9 75.8 33.4 21.0 33.0 47.7 27.9 23.4 33.9 36.3 36.2 39.3 33.6 46.5 33.2 92.8 34.5 48.6 34.3 38.6 53.3 65.7 32.2 47.3 60.5 97.9 50.8 49.6 84.8 62.1 191.6 78.4 74.6 92.0 81.2 77.4 67.6 42.7 58.3 86.8 123.8 62.2 87.9 101.7 118.6 72.3 48.9 94.1 80.8 144.3 90.9 64.7 57.0 38.3 106.4 116.7 109.5 70.3 93.7 43.3 100.3 112.0 111.8 85.8 77.8 58.0 79.3 80.4 50.4 70.8 83.6 30.3 91.7 81.5 47.0 36.7 64.1 82.5 74.7 87.6 35.3 72.4 92.7 78.8 63.0 114.7 70.0 64.5 46.9 59.6 85.6 54.4 92.5 4.1 5.3 1.9 1.6 4.3 3.2 2.0 1.8 1.5 3.3 3.5 1.5 2.8 5.6 1.1 4.2 2.3 2.3 1.6 30.4 31.6 29.3 36.0 32.4 27.0 34.6 29.0 33.4 33.6 34.5 47.3 36.6 25.6 23.6 45.7 27.2 33.1 37.5 18.0 18.2 37.7 29.3 22.1 23.3 17.2 19.6 22.0 25.0 31.0 26.5 28.2 15.6 17.5 162.3 32.7 34.9 29.1 34.1 13.3 114.2 21.5 17.5 26.8 39.8 65.8 12.7 30.4 23.6 22.9 24.1 43.7 74.9 20.4 12.2 92.8 33.6 333.2 15.5 67.3 19.6 119.9 48.4 43.3 19.6 109.6 116.0 32.6 18.0 11.7 22.7 39.4 31.3 27.4 15.5 35.4 19.7 83.8 21.7 72.6 18.4 25.0 32.1 39.7 24.0 20.6 22.2 57.9 AGT SERPINA8 ENSG00000135744 Angiotensinogen P01019 1 230690776-230745576 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Vasoactive, Vasoconstrictor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 1603.7" "Group enriched" "Detected in many" 9 "Cholangiocytes: 985.1;Hepatocytes: 2244.9" "Cancer enriched" "Detected in all" 4 "liver cancer: 1163.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Hep G2: 646.2;THP-1: 243.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025798 Supported "Secreted to blood" NA NA 5940000 65000000000 "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "CAB025798: " "unprognostic (7.77e-2)" "unprognostic (4.46e-1)" "unprognostic (2.15e-2)" "unprognostic (2.07e-2)" "unprognostic (2.67e-1)" "unprognostic (3.61e-2)" "unprognostic (5.75e-2)" "unprognostic (2.50e-1)" "unprognostic (2.20e-2)" "unprognostic (4.46e-2)" "unprognostic (4.32e-3)" "unprognostic (6.70e-2)" "unprognostic (9.28e-2)" "unprognostic (4.42e-3)" "unprognostic (2.17e-1)" "unprognostic (3.89e-1)" "unprognostic (1.38e-1)" 11.7 14.6 252.9 2.6 259.8 0.4 4.4 267.5 243.6 9.7 138.2 5.6 2.5 3.2 1.9 2.6 6.0 92.7 154.7 236.0 242.1 52.5 1603.7 5.1 1.0 352.4 314.4 3.5 7.9 6.0 25.8 0.7 304.9 16.3 3.6 26.4 4.9 2.2 43.6 2.0 9.7 5.8 340.5 1.3 4.9 4.1 273.5 1.7 13.2 25.8 0.1 7.0 4.5 322.4 0.2 0.4 0.2 0.2 15.6 0.0 0.9 0.6 0.2 0.0 0.0 80.6 0.1 0.3 0.7 0.2 0.7 0.7 0.0 0.0 0.0 11.4 0.2 0.2 0.3 646.2 1.9 1.0 0.5 26.3 0.0 0.0 0.1 0.1 0.0 0.1 0.1 5.5 0.7 0.0 0.2 0.6 0.6 0.1 0.2 0.3 2.4 0.1 0.1 0.3 0.9 0.6 0.4 0.1 5.5 0.1 0.0 243.6 0.1 0.4 1.3 0.4 1.2 3.5 47.0 0.4 0.4 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 252.9 259.8 267.5 243.6 236.0 242.1 352.4 314.4 304.9 340.5 273.5 322.4 0.8 0.0 1.7 140.0 11.3 0.6 1.1 0.0 0.0 4.7 0.8 0.3 60.0 985.1 0.6 3.7 35.5 0.1 0.0 0.0 25.4 169.8 62.2 0.3 0.4 5.5 0.0 50.8 0.3 10.0 0.2 27.2 0.5 0.1 0.0 0.0 39.3 2244.9 2.1 3.3 1.5 1.1 0.0 56.9 0.4 48.5 4.1 0.9 8.8 5.6 0.6 75.1 0.0 3.5 6.8 13.7 1.2 3.4 0.0 26.2 24.2 146.9 0.1 49.8 13.1 7.2 94.1 0.4 0.4 0.0 0.0 0.7 3.9 0.0 0.4 1.9 AGTPBP1 "CCP1, KIAA1035, Nna1" ENSG00000135049 "ATP/GTP binding protein 1" Q9UPW5 9 85546539-85742029 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 60.1;brain: 73.4;retina: 46.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 176.7;Inhibitory neurons: 163.0;Oligodendrocytes: 463.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057208, HPA071094" Approved Approved Nucleoli,Vesicles NA NA "Cluster 38: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoli, Vesicles" "HPA057208: AB_2683370, HPA071094: " "unprognostic (2.15e-1)" "unprognostic (3.78e-2)" "unprognostic (4.93e-3)" "unprognostic (6.12e-2)" "unprognostic (1.42e-1)" "unprognostic (8.95e-3)" "unprognostic (1.86e-2)" "unprognostic (1.65e-1)" "unprognostic (1.71e-1)" "unprognostic (8.26e-3)" "unprognostic (5.69e-3)" "unprognostic (6.31e-2)" "unprognostic (3.07e-2)" "unprognostic (1.11e-1)" "unprognostic (1.39e-1)" "unprognostic (9.60e-3)" "unprognostic (1.25e-1)" 8.4 5.5 31.1 9.5 44.3 60.1 6.2 23.2 36.3 4.7 0.0 5.1 3.7 4.9 3.9 5.3 4.6 5.3 12.2 20.1 30.3 6.9 4.6 14.4 9.4 30.5 28.6 3.6 6.7 7.5 5.3 6.1 31.5 4.7 5.8 46.5 4.1 3.0 16.5 6.2 5.1 6.5 32.0 14.8 5.5 14.1 34.3 12.4 5.8 20.5 8.4 5.7 4.3 73.4 5.1 9.6 27.9 11.1 5.6 6.0 10.6 7.4 6.4 7.4 8.4 5.2 8.6 31.3 6.2 7.7 13.2 2.9 13.0 9.4 6.9 33.6 11.8 5.3 11.5 9.3 11.8 24.5 6.2 5.8 10.8 7.0 23.5 4.8 11.9 15.9 6.7 24.5 3.3 8.0 19.3 14.5 19.3 18.1 6.8 17.3 10.2 9.8 12.8 5.4 33.5 23.7 8.4 9.1 15.4 26.1 3.5 7.8 12.0 4.8 8.5 30.4 8.9 16.7 14.8 14.3 10.1 23.5 9.8 37.4 14.4 12.7 9.0 8.4 8.8 2.3 4.4 7.0 15.6 1.7 3.7 7.0 21.2 6.8 6.7 2.5 5.1 9.6 31.1 44.3 23.2 36.3 20.1 30.3 30.5 28.6 31.5 32.0 34.3 73.4 22.3 64.1 12.8 46.0 14.3 7.9 2.6 2.9 8.0 38.0 4.7 4.8 48.3 0.0 13.8 3.7 102.2 4.1 41.8 4.3 7.9 5.7 52.5 29.3 8.6 12.0 7.7 16.8 176.7 4.0 4.3 6.9 9.2 22.0 27.1 9.2 8.2 3.7 8.1 35.3 163.0 5.6 6.1 35.4 24.1 53.9 1.8 42.8 3.6 61.8 46.6 16.7 47.4 82.9 463.5 5.1 1.2 2.6 26.2 3.8 3.2 9.8 14.7 59.1 13.1 9.3 10.4 46.6 29.2 9.2 10.7 2.9 26.3 6.4 4.7 2.3 AHCYL2 "IRBIT2, KIAA0828, long-IRBIT" ENSG00000158467 "Adenosylhomocysteinase like 2" Q96HN2 7 129225023-129430211 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "One-carbon metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "choroid plexus: 488.0;intestine: 177.4" "Cell type enhanced" "Detected in all" "Astrocytes: 567.4;Distal enterocytes: 334.0;Excitatory neurons: 131.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in all" 8 "HDLM-2: 235.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053128 Uncertain Approved Nucleoplasm,Cytosol NA NA 500000 "Cluster 40: NK-cells - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol Nucleoplasm "HPA053128: AB_2682050" "unprognostic (1.57e-1)" "unprognostic (2.91e-1)" "unprognostic (8.52e-3)" "unprognostic (1.71e-3)" "unprognostic (7.44e-3)" "prognostic favorable (4.17e-4)" "unprognostic (8.85e-2)" "unprognostic (1.43e-1)" "unprognostic (3.35e-1)" "unprognostic (2.74e-1)" "unprognostic (1.63e-1)" "unprognostic (6.79e-3)" "prognostic favorable (1.08e-7)" "unprognostic (4.70e-3)" "unprognostic (2.46e-1)" "unprognostic (7.21e-2)" "unprognostic (2.62e-1)" 7.1 10.2 25.4 15.6 35.9 3.2 8.4 27.2 34.4 10.6 488.0 157.4 57.8 9.1 7.2 9.6 7.4 55.8 4.6 47.3 32.5 28.5 7.7 65.8 10.8 30.3 28.1 11.4 13.7 19.2 21.3 12.1 22.5 9.3 177.4 57.8 30.6 7.0 37.3 24.3 38.6 11.8 27.8 7.0 41.9 10.5 39.0 9.4 42.6 27.7 9.4 16.1 7.6 25.2 8.7 13.5 25.4 15.3 6.8 9.9 5.4 6.8 9.4 7.5 6.6 7.9 5.7 5.3 6.9 7.4 15.9 6.0 12.8 10.7 8.3 235.7 16.0 12.4 14.5 6.4 4.0 9.3 15.4 9.1 13.5 6.0 9.1 12.7 15.1 10.1 5.8 28.7 9.9 8.2 13.7 12.1 12.7 8.6 9.5 9.0 6.9 14.4 15.0 11.5 11.6 7.3 15.5 6.5 9.3 21.0 6.1 6.6 8.6 6.4 3.6 16.9 7.2 12.0 14.6 7.2 16.4 9.8 9.9 0.1 0.4 0.7 0.3 0.9 0.4 0.3 0.5 0.2 0.4 0.1 0.4 0.1 0.1 1.3 0.4 0.1 1.8 0.2 25.4 35.9 27.2 34.4 47.3 32.5 30.3 28.1 22.5 27.8 39.0 25.2 4.7 60.9 98.6 567.4 9.3 15.6 5.1 7.2 31.3 10.8 4.8 4.3 7.3 18.6 16.4 5.5 6.2 12.5 2.2 334.0 11.7 4.5 61.7 5.9 5.3 5.2 9.1 3.4 131.2 5.3 2.9 3.6 30.1 8.7 5.7 6.0 5.7 6.0 4.7 5.0 115.5 32.9 6.1 10.0 6.1 30.6 4.1 7.3 24.9 99.3 7.7 91.0 2.1 127.2 77.5 6.2 71.8 6.8 7.4 6.2 27.0 17.1 8.7 5.9 6.6 5.1 4.3 5.1 2.3 17.8 9.8 15.2 7.3 8.3 46.1 15.1 AIFM1 "AIF, AUNX1, CMTX4, DFNX5, NAMSD, PDCD8" ENSG00000156709 "Apoptosis inducing factor mitochondria associated 1" O95831 X 130124666-130165879 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "DNA-binding, Oxidoreductase" "Charcot-Marie-Tooth disease, Deafness, Disease variant, Dwarfism, Mental retardation, Neurodegeneration, Neuropathy, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 165.4;Proximal tubular cells: 326.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003764, HPA030611" Enhanced Supported Mitochondria NA NA 230000 "Cluster 27: Non-specific - Gene expression" "Cluster 18: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "CAB003764: AB_289587, HPA030611: AB_2673549" "unprognostic (3.00e-3)" "unprognostic (1.34e-2)" "unprognostic (1.34e-1)" "unprognostic (1.22e-1)" "unprognostic (2.10e-2)" "unprognostic (3.15e-3)" "unprognostic (1.46e-1)" "unprognostic (1.14e-2)" "unprognostic (1.43e-1)" "unprognostic (3.11e-2)" "unprognostic (2.54e-3)" "unprognostic (2.81e-3)" "prognostic favorable (4.42e-10)" "unprognostic (1.76e-2)" "unprognostic (1.14e-1)" "unprognostic (5.04e-2)" "unprognostic (2.11e-2)" 21.0 65.2 10.5 17.6 11.2 11.8 17.8 11.9 12.8 15.7 24.7 34.3 52.9 15.3 8.9 20.8 22.1 10.1 107.7 10.9 11.6 97.3 110.6 13.9 16.2 11.3 11.0 11.9 27.8 29.7 16.2 10.3 11.4 14.8 15.9 8.5 18.6 7.6 68.9 15.2 29.9 10.1 11.2 20.3 41.2 30.3 12.1 18.5 14.7 25.2 11.0 18.4 13.4 11.6 52.8 95.4 22.6 85.2 24.1 14.6 50.0 28.6 19.0 33.5 25.2 55.8 36.4 105.0 113.3 17.5 39.3 47.2 61.3 33.3 12.7 48.2 73.4 61.6 59.1 68.9 34.0 51.5 63.5 26.1 21.7 34.5 22.0 12.1 27.2 83.4 62.6 50.7 13.1 96.7 57.6 74.5 24.4 53.6 65.1 55.6 31.7 132.7 60.8 36.6 46.0 28.2 35.5 68.0 67.5 13.2 46.0 40.8 31.7 20.5 20.4 63.9 58.7 24.2 45.0 47.5 25.3 86.4 33.4 4.1 21.0 14.1 11.8 26.6 13.1 14.6 12.8 14.6 31.7 10.3 12.7 12.6 2.4 20.7 24.8 14.7 17.9 12.4 10.5 11.2 11.9 12.8 10.9 11.6 11.3 11.0 11.4 11.2 12.1 11.6 12.6 16.0 20.1 17.0 17.1 8.7 8.2 25.0 9.1 19.3 13.0 8.3 165.4 22.8 21.2 40.5 22.9 58.0 14.2 31.6 92.0 24.9 1.8 36.7 17.3 11.5 9.6 26.3 10.8 20.5 29.0 16.4 27.0 50.4 10.8 33.1 14.3 92.3 38.0 15.2 12.1 24.0 34.6 14.4 7.4 4.9 17.4 16.8 10.6 8.4 16.6 17.2 20.6 8.0 19.6 18.0 18.9 17.3 19.2 7.9 45.6 326.1 21.3 48.1 6.6 11.3 39.3 10.2 32.0 17.1 6.8 39.7 15.8 45.9 37.2 9.8 AIMP2 "JTV-1, JTV1, p38, PRO0992" ENSG00000106305 "Aminoacyl tRNA synthetase complex interacting multifunctional protein 2" Q13155 7 6009255-6023834 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Differentiation, Protein biosynthesis" "Developmental protein" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 154.9;tongue: 102.5" "Cell type enhanced" "Detected in all" "Early spermatids: 134.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019098, HPA020057" Supported Approved Cytosol NA Yes 35000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "HPA019098: AB_1852040, HPA020057: AB_1852042" "unprognostic (1.24e-3)" "unprognostic (1.66e-2)" "unprognostic (7.30e-2)" "unprognostic (2.77e-2)" "unprognostic (1.51e-1)" "prognostic unfavorable (3.69e-4)" "unprognostic (9.29e-2)" "unprognostic (3.41e-2)" "unprognostic (8.75e-2)" "unprognostic (1.11e-1)" "unprognostic (5.13e-2)" "unprognostic (3.96e-1)" "prognostic favorable (1.38e-5)" "unprognostic (7.44e-2)" "unprognostic (8.97e-2)" "unprognostic (1.26e-2)" "prognostic unfavorable (3.09e-4)" 19.2 21.0 13.6 14.3 15.1 12.4 17.3 15.6 17.0 11.0 12.8 25.8 47.7 16.7 16.7 22.0 14.4 8.8 45.3 15.4 14.6 25.7 33.8 12.6 14.3 14.9 14.5 7.4 17.0 28.7 7.8 13.4 14.7 11.9 24.4 11.9 16.4 15.2 154.9 21.6 27.8 19.3 15.2 13.0 14.6 44.1 15.1 15.4 25.8 102.5 19.5 17.0 13.7 16.2 90.3 100.2 33.1 48.3 34.5 37.3 113.7 49.5 33.3 79.9 59.4 110.1 58.5 109.6 46.2 51.4 90.1 98.6 113.6 74.2 49.6 35.6 84.0 61.2 54.8 84.2 106.2 86.7 53.1 57.4 109.1 72.3 117.9 13.3 60.2 43.8 86.7 35.6 59.4 142.6 37.4 157.2 136.0 44.3 70.4 83.5 73.8 93.3 119.1 41.7 66.1 62.6 50.4 101.3 72.9 41.9 94.5 70.1 51.8 46.0 112.9 77.0 111.2 44.5 73.9 95.5 38.5 122.3 75.6 46.7 61.4 19.5 41.5 77.5 34.9 47.3 27.7 32.5 92.4 31.9 27.1 28.9 6.0 48.3 57.9 58.7 32.3 43.4 13.6 15.1 15.6 17.0 15.4 14.6 14.9 14.5 14.7 15.2 15.1 16.2 15.0 9.6 10.3 8.1 13.0 10.8 22.5 58.5 24.5 10.2 11.8 15.1 2.2 28.6 40.2 12.9 6.2 50.8 10.1 17.6 70.5 52.6 134.7 25.3 23.9 20.0 6.7 24.2 5.8 57.3 64.0 15.1 23.4 20.6 12.6 16.7 13.2 38.8 50.0 6.7 6.7 18.2 57.0 19.1 14.3 84.5 19.9 18.1 19.6 1.9 40.3 17.8 17.5 5.0 10.4 40.1 14.5 18.0 23.8 23.0 59.3 67.7 34.9 11.2 13.1 16.0 24.5 91.1 26.8 37.1 11.6 39.5 12.6 38.0 39.8 17.8 AIPL1 LCA4 ENSG00000129221 "Aryl hydrocarbon receptor interacting protein like 1" Q9NZN9 17 6393693-6435199 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Disease variant, Leber congenital amaurosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1012 "retina: 836.0" "Cell type enriched" "Detected in some" 4 "Rod photoreceptor cells: 1926.4" "Cancer enriched" "Detected in single" 12 "testis cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 1.5;OE19: 2.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA026578 Enhanced Uncertain Nucleoplasm,Cytosol NA NA "Cluster 79: Retina - Phototransduction" "Cluster 21: OE19 - Mitochondria" "Cluster 46: Photoreceptor cells - Phototransduction" "Nucleoplasm, Cytosol" "HPA026578: AB_2671905" "unprognostic (2.42e-2)" "unprognostic (1.17e-1)" "unprognostic (2.02e-2)" "unprognostic (1.68e-3)" "unprognostic (3.24e-1)" "unprognostic (1.13e-3)" "unprognostic (3.76e-1)" "unprognostic (5.35e-2)" 0.0 0.0 0.2 0.1 0.3 0.7 0.0 0.2 0.3 0.0 0.5 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 836.0 0.4 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.6 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.4 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.3 2.8 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.2 0.3 0.2 0.3 0.1 0.8 0.2 0.1 0.3 0.0 0.3 0.6 0.0 3.2 1.1 0.0 0.0 0.8 1.0 0.0 0.0 139.2 0.1 0.0 0.6 0.0 1.4 0.0 412.8 0.1 0.1 0.2 0.0 0.0 7.8 0.4 0.2 8.5 0.0 0.0 0.3 0.0 0.1 0.3 0.0 0.4 0.0 0.1 1.4 0.0 0.1 65.6 0.2 0.2 0.0 0.3 1.1 1.3 0.0 0.3 1.8 0.0 0.0 256.1 0.0 0.5 0.1 0.1 0.0 0.4 0.0 0.7 0.0 0.0 0.0 1926.4 0.0 1.8 0.3 0.4 0.2 0.0 0.4 0.3 0.4 0.1 0.0 1.7 AKAP12 "AKAP250, SSeCKS" ENSG00000131016 "A-kinase anchoring protein 12" Q02952 6 151239967-151358559 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Calmodulin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 352.6;Endothelial cells: 278.4;Fibroblasts: 270.0;Muller glia cells: 583.0;Pancreatic endocrine cells: 322.1;Spermatocytes: 325.4" "Cancer enhanced" "Detected in all" "testis cancer: 39.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 235 "basophil: 37.2" "Lineage enriched" "Detected in single" 235 "granulocytes: 37.2" "Cell line enhanced" "Detected in many" "REH: 193.0;TIME: 188.2;U-251 MG: 202.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006344, CAB026379, HPA056230" Enhanced Enhanced "Plasma membrane,Cytosol" No No 10000000 "Cluster 38: Basophils - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane, Cytosol" "CAB026379: , HPA006344: AB_1078118, HPA056230: AB_2683073" "unprognostic (6.66e-2)" "unprognostic (1.51e-1)" "unprognostic (9.90e-3)" "prognostic unfavorable (7.08e-4)" "unprognostic (2.61e-2)" "unprognostic (8.88e-2)" "unprognostic (5.05e-2)" "prognostic unfavorable (6.34e-5)" "unprognostic (1.34e-1)" "unprognostic (8.26e-3)" "unprognostic (2.59e-1)" "unprognostic (4.72e-2)" "unprognostic (4.51e-3)" "unprognostic (1.10e-3)" "unprognostic (3.51e-1)" "unprognostic (7.03e-3)" "unprognostic (2.34e-2)" 105.6 16.0 13.8 17.1 16.6 2.2 59.7 99.7 57.5 19.8 4.5 60.1 8.6 31.1 9.3 18.6 31.2 31.5 51.8 14.7 66.8 35.8 30.6 44.3 6.9 67.0 35.3 87.8 10.8 1.6 23.3 38.3 74.7 23.1 13.2 109.4 6.5 20.8 11.9 9.4 24.9 42.9 10.9 14.3 25.6 100.0 39.4 5.9 22.1 14.5 3.4 33.0 21.2 24.3 7.8 37.8 53.2 0.1 98.2 145.9 18.8 43.9 23.7 19.3 19.4 0.9 141.6 0.0 17.1 33.2 160.4 1.0 102.2 32.5 17.2 50.2 37.6 0.6 40.8 35.6 10.9 0.0 9.6 104.0 0.0 81.9 4.3 25.4 127.8 0.6 9.8 0.9 70.7 0.5 0.3 0.1 33.3 0.1 43.9 193.0 2.3 0.2 110.2 6.3 37.9 22.0 14.1 0.5 24.9 74.6 2.8 0.5 188.2 2.6 34.0 110.4 202.9 0.4 0.1 0.2 63.2 0.1 37.4 37.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.8 16.6 99.7 57.5 14.7 66.8 67.0 35.3 74.7 10.9 39.4 24.3 352.6 12.8 16.2 34.3 6.8 19.6 19.6 63.2 1.2 14.5 1.2 3.9 12.1 5.7 31.1 51.5 2.1 2.4 0.9 1.2 1.9 107.0 101.4 14.2 195.4 278.4 1.8 3.2 75.8 6.7 10.1 270.0 3.6 31.6 64.2 14.7 194.5 4.8 26.9 0.0 33.3 0.7 4.1 15.7 45.4 116.3 39.7 13.9 58.7 37.5 0.6 583.0 1.0 59.8 5.1 322.1 1.1 110.6 6.7 49.5 0.0 89.4 6.0 31.0 98.6 208.3 243.0 325.4 33.0 1.6 11.4 10.0 5.1 9.3 2.5 105.3 AKAP14 AKAP28 ENSG00000186471 "A-kinase anchoring protein 14" Q86UN6 X 119895837-119920716 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 44.0;testis: 83.9" "Group enriched" "Detected in some" 4 "Early spermatids: 485.6;Late spermatids: 1648.3" "Cancer enhanced" "Detected in some" "endometrial cancer: 2.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 1.6;SCLC-21H: 2.4;SuSa: 1.5" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA060999 Enhanced NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 31: Spermatids - Spermatogenesis" "HPA060999: AB_2684407" "unprognostic (1.36e-2)" "unprognostic (2.36e-2)" "unprognostic (2.82e-2)" "unprognostic (1.25e-3)" "unprognostic (1.52e-1)" "unprognostic (1.95e-1)" "unprognostic (4.16e-1)" "unprognostic (4.68e-2)" "unprognostic (2.20e-1)" "unprognostic (1.02e-2)" "unprognostic (2.72e-1)" "unprognostic (3.73e-2)" "unprognostic (3.17e-1)" "unprognostic (1.24e-1)" "unprognostic (1.80e-1)" 0.0 0.0 1.0 0.0 1.0 0.2 0.1 1.0 0.8 1.2 16.1 0.1 0.3 0.7 0.1 0.0 44.0 0.0 0.0 1.4 2.2 0.0 0.1 3.2 0.0 3.4 3.7 0.1 0.0 0.0 0.7 0.0 2.5 0.1 0.0 1.2 0.0 0.1 0.1 0.0 0.4 0.0 1.4 0.0 0.0 83.9 3.7 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.7 0.1 0.0 0.2 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.2 2.4 0.0 0.0 0.0 0.0 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.0 1.0 0.8 1.4 2.2 3.4 3.7 2.5 1.4 3.7 1.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 18.7 0.0 0.5 0.0 0.0 0.0 0.0 17.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 485.6 133.5 1.1 0.3 0.0 0.0 0.6 0.0 0.3 0.2 0.0 1.8 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 22.4 0.0 0.0 1648.3 2.5 0.8 0.0 1.0 0.0 0.2 0.0 1.5 0.2 0.0 0.1 7.2 0.0 0.0 0.1 0.1 224.1 0.1 13.1 0.0 4.9 14.0 2.7 0.0 0.0 0.0 0.1 0.0 0.1 0.1 AKAP4 "AKAP82, CT99, Fsc1, hAKAP82, HI, p82" ENSG00000147081 "A-kinase anchoring protein 4" Q5JQC9 X 50190777-50201007 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1023 "testis: 195.7" "Group enriched" "Detected in some" 137 "Early spermatids: 778.9;Late spermatids: 2587.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA005949, HPA020046" Enhanced NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 31: Spermatids - Spermatogenesis" "HPA005949: AB_1078120, HPA020046: AB_1844693" "unprognostic (2.94e-2)" "unprognostic (1.86e-2)" "unprognostic (2.47e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 195.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 778.9 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2587.5 11.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 12.2 6.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 AKAP6 "ADAP6, AKAP100, KIAA0311, mAKAP, PRKA6" ENSG00000151320 "A-kinase anchoring protein 6" Q13023 14 32329298-32837684 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 59.8;heart muscle: 54.6;skeletal muscle: 47.5;tongue: 50.7" "Group enriched" "Detected in many" 6 "Excitatory neurons: 601.6;Inhibitory neurons: 663.1;Oligodendrocyte precursor cells: 412.7;Oligodendrocytes: 1162.5" "Cancer enhanced" "Detected in many" "glioma: 2.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "naive B-cell: 3.5" "Lineage enriched" "Detected in single" 6 "B-cells: 3.5" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 15.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001983, HPA048741" Enhanced NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "CAB001983: , HPA048741: AB_2680506" "unprognostic (1.99e-1)" "unprognostic (9.92e-2)" "unprognostic (1.88e-1)" "unprognostic (1.37e-1)" "unprognostic (2.52e-1)" "unprognostic (4.33e-2)" "unprognostic (1.41e-4)" "unprognostic (1.81e-3)" "unprognostic (1.93e-2)" "unprognostic (4.49e-3)" "unprognostic (1.24e-3)" "unprognostic (3.54e-1)" "unprognostic (3.33e-16)" "unprognostic (8.57e-2)" "unprognostic (1.27e-1)" "unprognostic (5.14e-3)" "unprognostic (1.79e-3)" 1.6 5.6 21.0 2.5 31.4 0.5 4.6 20.3 24.6 1.6 0.0 5.5 1.8 3.9 5.6 5.4 2.9 3.7 54.6 16.9 36.7 2.9 2.1 2.3 0.8 52.0 34.9 2.5 0.8 3.5 3.6 4.5 51.9 2.0 2.2 13.6 2.6 1.2 47.5 1.2 2.4 7.7 22.4 0.8 2.0 5.9 34.8 0.9 4.8 50.7 0.7 4.2 1.5 59.8 0.3 0.8 1.0 0.9 0.2 1.7 0.2 1.3 3.6 0.2 0.4 1.1 1.0 1.4 0.9 15.8 0.6 0.8 1.2 1.4 0.5 1.3 1.0 1.3 1.5 1.1 0.5 0.1 0.3 1.8 1.3 0.0 0.4 0.6 0.1 2.1 0.3 4.1 1.1 0.8 0.7 0.2 0.2 1.1 1.1 0.7 4.9 0.6 0.4 1.2 5.2 4.2 1.1 0.7 3.2 0.7 2.9 0.1 0.3 0.2 0.8 0.8 0.5 2.5 2.4 0.6 1.5 0.1 5.4 0.3 0.1 0.0 0.0 0.1 0.1 0.2 0.0 0.2 0.2 3.5 0.4 0.6 0.5 0.1 0.1 0.4 0.0 0.3 21.0 31.4 20.3 24.6 16.9 36.7 52.0 34.9 51.9 22.4 34.8 59.8 0.6 6.4 2.7 111.3 2.2 2.3 2.9 1.0 5.2 49.2 8.7 3.0 108.0 0.0 4.9 1.8 50.1 0.8 0.1 1.1 0.0 0.8 32.4 6.7 0.4 1.7 1.2 0.0 601.6 0.5 0.3 6.3 0.0 1.4 1.3 0.6 1.1 2.7 1.2 26.9 663.1 0.6 4.1 0.6 1.6 13.7 14.6 1.1 7.2 23.4 0.7 2.5 0.0 412.7 1162.5 0.3 0.1 33.1 2.0 1.1 1.9 1.5 23.6 21.5 19.7 25.8 14.3 25.9 1.3 1.1 1.6 0.4 0.6 3.4 0.9 0.9 AKNA KIAA1968 ENSG00000106948 "AT-hook transcription factor" Q7Z591 9 114334156-114394405 "Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 110.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 148.0;dendritic cells: 240.0;NK-cells: 265.7;Plasma cells: 137.3;Rod photoreceptor cells: 140.1;T-cells: 145.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 108.4;MOLT-4: 98.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA052367, HPA063993" Supported Nucleoplasm,Centrosome NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Centrosome" "HPA052367: AB_2681801, HPA063993: AB_2685169" "unprognostic (5.19e-3)" "prognostic favorable (1.22e-4)" "unprognostic (5.38e-3)" "prognostic favorable (2.14e-5)" "unprognostic (3.12e-1)" "prognostic favorable (1.25e-4)" "unprognostic (1.88e-1)" "unprognostic (3.28e-2)" "unprognostic (4.13e-2)" "unprognostic (6.62e-2)" "unprognostic (5.85e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (2.55e-5)" "unprognostic (1.19e-2)" "unprognostic (6.61e-3)" "unprognostic (2.93e-1)" "prognostic favorable (2.29e-4)" 23.3 8.5 13.1 54.5 14.3 50.6 18.9 12.9 14.9 49.6 21.0 20.5 16.2 37.2 5.8 8.8 37.4 14.6 8.4 11.1 14.5 10.3 19.2 32.0 82.4 22.7 21.2 28.0 10.4 2.9 11.4 8.5 17.2 16.9 11.9 36.0 9.2 11.0 3.0 7.7 52.5 22.6 16.3 110.6 21.4 7.8 15.2 75.2 11.5 3.6 61.6 17.6 18.3 14.1 4.7 4.8 5.9 3.7 36.9 4.4 25.1 5.0 6.2 4.8 4.0 7.8 4.9 57.9 4.7 4.3 8.2 10.7 3.7 1.4 1.3 108.4 2.3 6.0 2.4 5.6 42.2 57.5 59.5 8.0 8.1 4.0 3.8 6.7 8.7 49.9 5.3 61.9 2.0 7.5 98.0 63.2 20.1 10.2 5.8 60.4 1.0 12.8 40.3 2.3 2.7 5.2 1.3 4.0 13.4 6.3 11.5 29.2 14.2 2.2 4.8 0.8 4.2 12.5 15.4 47.0 2.8 27.6 2.2 11.5 7.9 12.6 18.9 5.7 14.8 7.6 10.3 16.9 5.0 7.9 9.0 12.1 19.6 14.6 5.5 10.5 8.7 10.3 13.1 14.3 12.9 14.9 11.1 14.5 22.7 21.2 17.2 16.3 15.2 14.1 13.5 12.8 22.8 2.6 76.0 5.2 6.9 1.6 6.2 36.4 7.4 5.3 4.1 4.3 8.3 23.9 148.0 9.5 240.0 9.5 0.0 3.7 17.5 34.8 14.4 9.7 12.7 34.3 2.6 8.1 6.2 8.8 17.9 12.4 33.5 16.6 12.1 9.6 18.2 5.0 8.4 18.9 2.0 59.1 31.5 26.2 14.6 43.0 5.4 19.7 67.2 7.0 265.7 20.1 4.9 5.4 9.2 6.8 137.3 7.8 12.6 0.9 40.7 140.1 0.0 5.8 13.6 1.1 0.9 1.9 3.4 3.4 145.7 2.8 13.4 9.3 AKT2 PKBβ ENSG00000105221 "AKT serine/threonine kinase 2" P31751 19 40230317-40285536 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Carbohydrate metabolism, Glucose metabolism, Glycogen biosynthesis, Glycogen metabolism, Sugar transport, Translation regulation, Transport" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Diabetes mellitus, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004204, HPA064521" Uncertain Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Vesicles, Cytosol" "CAB004204: AB_626659, HPA064521: AB_2685278" "unprognostic (6.13e-2)" "unprognostic (2.21e-1)" "unprognostic (1.56e-1)" "prognostic unfavorable (1.05e-6)" "unprognostic (2.85e-1)" "unprognostic (6.40e-3)" "unprognostic (9.59e-2)" "unprognostic (1.22e-2)" "unprognostic (2.98e-2)" "unprognostic (2.49e-2)" "unprognostic (3.02e-1)" "prognostic unfavorable (4.74e-4)" "unprognostic (1.30e-2)" "unprognostic (1.89e-1)" "unprognostic (3.28e-1)" "unprognostic (6.16e-2)" "unprognostic (2.00e-1)" 62.8 40.0 31.7 37.3 31.3 48.4 38.6 58.3 40.0 49.8 55.1 42.3 24.5 43.5 49.4 42.5 46.1 25.1 40.8 31.5 24.5 52.2 59.2 30.7 38.1 32.0 26.0 53.9 41.9 58.5 47.8 27.6 26.3 41.2 23.3 41.2 32.5 45.0 101.3 39.4 35.6 34.2 22.1 38.1 33.1 29.7 28.0 53.4 100.1 118.7 37.0 39.8 41.5 35.2 66.2 160.1 63.1 61.5 72.0 88.9 32.5 41.7 63.5 87.6 77.9 71.8 60.8 67.4 36.8 96.3 37.2 28.2 66.8 90.0 56.1 62.5 74.3 43.4 116.5 44.7 45.8 50.7 50.5 82.7 53.6 58.6 56.4 71.9 19.0 73.0 57.3 67.5 49.8 54.6 81.1 24.7 31.7 73.7 41.5 54.2 32.1 48.5 68.3 105.7 82.7 49.8 43.3 75.0 35.0 62.5 59.8 64.9 18.8 52.7 51.5 47.3 67.6 61.5 59.0 56.4 52.6 59.7 44.3 5.7 2.6 2.1 2.2 1.2 2.2 1.9 1.8 1.5 1.7 2.9 1.7 2.6 4.0 1.7 1.6 4.9 1.6 1.7 31.7 31.3 58.3 40.0 31.5 24.5 32.0 26.0 26.3 22.1 28.0 35.2 18.1 16.0 15.9 51.2 33.0 23.8 23.9 20.9 26.2 67.6 25.3 23.9 31.2 30.0 18.1 60.7 41.7 31.3 26.0 23.7 21.5 19.7 5.5 26.2 26.7 17.4 19.2 19.1 30.4 30.4 25.2 27.9 20.9 25.8 14.0 44.2 13.9 87.5 22.3 60.6 25.3 20.1 22.4 23.2 17.5 10.5 42.9 20.0 23.2 23.4 21.7 46.2 50.4 41.7 40.6 24.8 16.9 26.7 30.4 29.7 21.8 24.8 24.9 97.4 19.7 29.3 25.0 14.8 15.6 31.1 27.4 38.7 23.1 56.9 23.3 29.4 AL451007.3 ENSG00000284188 "Novel protein" 1 244729898-244730962 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 19 "testis: 8.9" "Cell type enriched" "Detected in single" 4 "Distal tubular cells: 3.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 39: Non-specific - Basic cellular processes" 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.3 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.1 8.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.3 0.2 0.2 0.1 0.2 0.2 0.1 0.3 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 ALAD "ALADH, PBGS" ENSG00000148218 "Aminolevulinate dehydratase" P13716 9 113386312-113401290 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Heme biosynthesis, Porphyrin biosynthesis" "Allosteric enzyme, Lyase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 209.8" "Cell type enhanced" "Detected in all" "Erythroid cells: 147.8;Granulosa cells: 86.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021023, HPA022124" Enhanced Approved Cytosol NA NA 44000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 35: Non-specific - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 6: Erythroid cells - Oxygen transport" Cytosol "HPA021023: AB_1844716, HPA022124: AB_1844717" "unprognostic (2.75e-1)" "unprognostic (6.26e-2)" "prognostic unfavorable (7.33e-5)" "prognostic favorable (5.64e-4)" "unprognostic (4.16e-2)" "unprognostic (9.49e-2)" "prognostic favorable (8.80e-5)" "unprognostic (2.87e-3)" "unprognostic (3.49e-1)" "unprognostic (2.95e-1)" "unprognostic (1.62e-1)" "unprognostic (3.31e-2)" "prognostic favorable (1.65e-4)" "unprognostic (1.75e-1)" "unprognostic (1.22e-1)" "unprognostic (3.40e-1)" "unprognostic (1.31e-2)" 54.7 153.9 73.5 16.8 82.7 82.2 23.2 75.2 84.7 18.4 53.6 25.7 29.5 16.3 26.6 35.0 15.6 27.4 51.9 66.0 74.5 73.2 209.8 20.6 15.6 85.4 83.5 28.9 46.5 73.2 15.9 24.9 84.5 34.1 24.5 19.0 98.6 24.2 28.8 38.9 26.6 17.6 80.1 13.6 50.4 13.1 81.1 20.3 25.9 23.9 18.7 18.4 19.3 83.7 8.1 14.8 11.0 15.7 71.2 48.4 67.8 21.9 35.4 13.7 17.2 19.2 16.7 11.7 12.7 30.3 11.0 29.1 8.1 14.6 8.3 29.5 10.2 22.0 18.2 26.2 16.4 21.2 19.0 41.2 10.8 12.7 5.5 53.9 27.1 18.6 8.9 16.5 23.7 61.8 23.8 21.2 5.4 57.9 27.4 19.5 18.7 19.8 21.4 16.6 10.2 9.4 27.2 32.5 20.1 19.2 34.1 23.7 30.7 12.5 9.3 25.1 12.4 23.8 26.0 9.8 34.1 18.9 13.6 10.2 13.7 23.6 11.3 15.5 6.0 6.8 9.3 6.0 14.6 10.2 8.7 9.9 6.2 6.9 17.4 6.0 10.8 9.7 73.5 82.7 75.2 84.7 66.0 74.5 85.4 83.5 84.5 80.1 81.1 83.7 7.2 16.0 15.6 18.6 10.4 7.0 8.9 7.1 8.0 12.9 16.7 11.6 50.3 25.8 12.0 14.7 27.1 48.2 7.4 27.7 13.7 20.3 5.4 17.7 9.2 11.5 9.1 147.8 10.0 26.3 23.2 10.2 15.3 27.7 14.5 86.5 11.0 70.0 17.0 5.0 10.7 12.5 10.2 15.1 6.4 10.8 11.8 12.4 12.4 9.4 12.4 6.4 8.2 7.1 20.0 15.0 35.3 14.7 11.0 7.6 32.6 59.0 10.6 15.7 6.6 8.9 24.6 6.8 9.5 22.6 9.1 11.4 8.8 11.7 16.7 9.2 ALDH3A2 "ALDH10, FALDH, SLS" ENSG00000072210 "Aldehyde dehydrogenase 3 family member A2" P51648 17 19648136-19685760 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease variant, Ichthyosis, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 288.6" "Cell type enhanced" "Detected in all" "Basal squamous epithelial cells: 287.4;Squamous epithelial cells: 232.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "OE19: 285.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014769, CAB020692" Enhanced Approved "Endoplasmic reticulum,Cytosol" NA NA 32000 "Cluster 14: Monocytes - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "Endoplasmic reticulum, Cytosol" "CAB020692: , HPA014769: AB_1844728" "unprognostic (1.42e-1)" "unprognostic (7.62e-2)" "unprognostic (7.77e-2)" "unprognostic (2.49e-2)" "unprognostic (4.59e-1)" "unprognostic (1.64e-1)" "unprognostic (1.59e-1)" "unprognostic (1.31e-2)" "unprognostic (2.23e-1)" "unprognostic (3.93e-3)" "unprognostic (2.40e-1)" "unprognostic (2.63e-1)" "prognostic favorable (3.85e-8)" "unprognostic (4.12e-2)" "unprognostic (1.55e-1)" "unprognostic (1.42e-2)" "unprognostic (1.26e-1)" 75.2 203.0 23.1 15.2 32.5 9.3 34.9 24.8 27.7 49.4 71.7 49.6 68.1 29.4 41.7 131.3 38.3 70.5 44.6 29.0 27.9 173.0 288.6 59.1 14.9 23.3 26.3 32.3 52.3 40.6 21.9 11.8 23.5 75.0 36.5 40.8 61.7 41.5 53.0 207.6 71.8 30.2 25.1 19.4 81.5 26.9 24.8 23.0 75.1 100.9 36.4 24.2 40.5 33.6 27.7 147.0 29.2 58.5 88.7 89.4 19.1 12.3 29.9 24.4 27.6 63.2 52.5 12.3 35.9 50.5 29.3 99.0 59.8 125.2 19.9 36.2 42.5 5.3 120.9 142.8 12.2 30.6 5.4 42.9 137.6 22.9 12.2 49.7 49.2 25.5 2.2 0.6 37.3 45.3 0.7 25.2 32.3 285.4 78.5 38.6 64.1 25.3 17.5 132.3 46.3 30.4 98.9 38.4 35.3 152.2 78.1 35.0 46.7 10.1 28.7 68.8 45.6 11.3 28.6 15.5 47.4 0.3 48.3 0.8 21.1 17.5 6.3 18.3 9.9 5.2 6.0 6.1 20.7 4.9 6.8 6.3 2.2 15.0 20.6 1.3 11.3 11.0 23.1 32.5 24.8 27.7 29.0 27.9 23.3 26.3 23.5 25.1 24.8 33.6 22.1 176.3 86.5 14.7 13.3 57.1 143.9 85.1 287.4 15.3 13.6 24.0 54.1 105.8 86.5 33.1 12.5 12.5 8.2 48.9 43.0 97.5 79.6 47.5 13.4 19.5 16.2 8.2 30.5 52.0 4.6 39.9 87.7 36.9 29.7 34.6 13.6 116.7 24.6 6.7 20.1 27.7 26.4 21.7 15.1 19.5 55.9 23.5 7.2 13.1 25.7 105.9 8.2 19.6 29.1 43.9 28.7 80.5 28.6 104.2 90.6 119.2 59.2 21.4 13.1 70.1 22.1 15.5 24.0 232.6 90.2 1.4 13.2 29.1 46.0 51.4 ALDH6A1 MMSDH ENSG00000119711 "Aldehyde dehydrogenase 6 family member A1" Q02252 14 74056847-74084492 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "kidney: 379.1;liver: 367.1" "Cell type enhanced" "Detected in all" "Distal tubular cells: 201.5;Hepatocytes: 523.6;Proximal tubular cells: 962.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 43.2" "Lineage enriched" "Detected in all" 4 "granulocytes: 43.2" "Cell line enhanced" "Detected in all" "T-47d: 57.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029072, HPA029073, HPA029074, HPA029075" Enhanced Enhanced Mitochondria No No 37000 "Cluster 2: Granulocytes - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 6: T47d - Mammary gland" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA029072: AB_10599176, HPA029073: AB_10601877, HPA029074: AB_10601000, HPA029075: AB_10602005" "unprognostic (1.45e-1)" "unprognostic (5.38e-2)" "unprognostic (6.89e-2)" "unprognostic (6.95e-3)" "unprognostic (1.46e-1)" "unprognostic (7.93e-2)" "unprognostic (1.11e-3)" "prognostic favorable (4.22e-4)" "unprognostic (1.58e-1)" "unprognostic (9.10e-2)" "unprognostic (3.11e-2)" "unprognostic (2.13e-1)" "prognostic favorable (2.00e-15)" "unprognostic (4.59e-1)" "unprognostic (1.92e-1)" "unprognostic (6.05e-3)" "unprognostic (1.12e-1)" 38.7 14.7 58.6 4.8 66.0 3.3 14.4 58.8 59.3 17.3 61.4 15.2 26.6 11.4 9.8 9.8 12.8 9.4 40.3 51.0 54.0 379.1 367.1 9.4 5.1 63.3 54.0 28.3 23.4 37.0 6.6 7.6 55.6 25.4 15.8 15.2 19.8 16.1 27.5 6.2 23.4 9.0 56.4 5.4 24.0 17.1 69.8 5.7 28.3 34.8 5.3 11.4 7.0 62.6 8.9 7.8 11.0 23.5 39.3 19.2 17.5 6.3 11.8 6.8 11.5 17.3 10.2 10.5 13.6 13.5 5.3 4.8 24.9 7.0 14.5 9.5 3.5 5.1 8.0 19.2 45.0 2.7 2.4 28.2 12.0 8.7 20.7 17.0 12.0 23.7 8.1 14.7 4.6 36.2 7.6 4.0 8.7 32.6 5.2 15.1 11.2 14.6 9.2 5.8 4.4 7.0 21.0 21.9 5.7 18.0 57.5 9.6 3.8 7.4 9.0 11.7 2.4 9.3 18.9 10.2 9.9 3.2 7.3 29.1 6.2 43.2 6.9 4.8 10.6 7.2 7.8 8.4 9.2 6.1 9.9 7.0 2.4 9.7 4.2 5.3 6.1 4.9 58.6 66.0 58.8 59.3 51.0 54.0 63.3 54.0 55.6 56.4 69.8 62.6 15.4 38.5 60.4 24.5 11.8 9.2 26.8 10.0 20.5 20.6 28.4 18.9 81.4 67.2 22.9 66.2 4.2 31.0 7.1 18.9 201.5 11.6 23.4 26.2 27.5 27.0 16.9 28.6 5.5 3.1 14.8 25.9 34.7 90.2 7.6 27.1 87.4 523.6 17.7 11.8 10.0 39.3 8.2 26.5 8.9 19.0 28.9 13.4 24.9 1.9 15.8 98.5 9.2 12.5 23.4 4.1 16.3 48.2 8.0 27.6 55.3 962.4 15.4 17.0 13.1 25.6 16.9 11.0 4.2 25.2 7.4 30.6 11.0 10.2 35.7 17.2 ALG1 "CDG1K, HMAT1, HMT-1, Mat-1" ENSG00000033011 "ALG1 chitobiosyldiphosphodolichol beta-mannosyltransferase" Q9BT22 16 5033923-5087379 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060392 Approved Approved "Nucleoli fibrillar center,Endoplasmic reticulum" "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 29: Non-specific - Vesicular transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "Nucleoli fibrillar center" "HPA060392: AB_2684273" "unprognostic (1.66e-2)" "unprognostic (5.18e-1)" "prognostic favorable (5.79e-4)" "unprognostic (1.55e-2)" "unprognostic (2.10e-2)" "unprognostic (3.22e-2)" "unprognostic (2.84e-2)" "unprognostic (2.52e-1)" "unprognostic (1.18e-2)" "unprognostic (1.17e-1)" "unprognostic (2.15e-1)" "unprognostic (2.87e-1)" "unprognostic (5.27e-2)" "unprognostic (1.02e-2)" "prognostic unfavorable (6.93e-4)" "unprognostic (2.58e-3)" "unprognostic (3.86e-2)" 11.3 19.6 6.2 12.8 6.6 7.7 9.9 6.1 7.9 12.4 12.7 18.8 15.8 11.0 14.5 11.2 12.4 9.8 8.3 6.5 6.6 12.6 21.0 9.3 12.4 6.3 6.0 8.8 26.8 17.5 10.9 9.5 6.9 10.5 16.3 6.8 18.8 10.6 7.4 8.8 13.1 12.0 5.8 15.0 19.6 20.8 6.5 12.0 11.6 5.5 12.1 12.4 8.3 6.8 24.0 53.7 10.8 25.5 40.7 24.2 26.4 50.6 50.6 46.9 46.4 44.8 72.4 44.4 43.1 48.0 20.7 58.2 30.1 36.2 31.6 42.0 43.3 20.7 40.1 87.1 33.4 37.6 37.3 29.7 26.9 36.2 23.0 18.5 28.7 32.2 29.5 44.7 34.5 50.1 28.9 40.7 51.2 31.7 33.6 48.8 16.0 124.9 28.3 18.7 20.7 21.7 49.3 67.8 27.4 14.3 45.1 29.2 29.8 22.5 25.6 134.7 40.1 39.8 59.3 30.2 20.5 39.8 38.1 11.5 79.9 28.8 87.2 80.6 77.1 72.9 74.9 86.3 86.7 73.9 66.7 75.0 4.3 79.8 80.0 75.6 81.1 126.6 6.2 6.6 6.1 7.9 6.5 6.6 6.3 6.0 6.9 5.8 6.5 6.8 4.6 16.0 6.1 4.2 11.2 2.4 3.4 15.7 5.2 7.4 6.8 6.0 0.7 8.6 14.3 7.3 12.5 16.2 7.2 8.5 3.9 19.5 10.7 5.4 8.1 8.7 13.3 12.0 4.0 28.3 18.7 9.3 13.7 5.5 1.3 8.1 8.6 17.7 21.7 3.3 4.6 21.0 8.2 10.6 2.4 25.5 9.6 7.6 10.6 1.0 9.3 7.5 9.2 3.5 3.4 21.6 11.1 6.8 22.7 4.5 11.8 10.4 11.7 6.3 6.6 5.4 7.1 28.0 16.0 7.7 1.6 8.5 8.6 13.8 18.0 4.4 ALG8 MGC2840 ENSG00000159063 "ALG8 alpha-1,3-glucosyltransferase" Q9BVK2 11 78095244-78139660 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 105.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051898 Approved Approved Nucleoplasm NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 23: Testis - Cell cycle regulation" "Cluster 21: OE19 - Mitochondria" "Cluster 55: Plasma cells - Humoral immune response" Nucleoplasm "HPA051898: AB_2681656" "unprognostic (1.37e-1)" "unprognostic (9.24e-2)" "unprognostic (4.60e-2)" "unprognostic (2.69e-2)" "unprognostic (2.65e-1)" "unprognostic (6.49e-2)" "unprognostic (5.38e-3)" "unprognostic (5.91e-2)" "unprognostic (1.39e-1)" "unprognostic (1.10e-3)" "unprognostic (5.29e-2)" "unprognostic (1.20e-1)" "unprognostic (1.35e-2)" "unprognostic (1.19e-1)" "unprognostic (2.34e-1)" "unprognostic (3.78e-2)" "unprognostic (6.37e-2)" 22.8 33.0 12.7 13.4 14.3 9.2 25.6 13.9 16.4 18.7 15.4 17.5 13.3 15.9 33.2 19.0 18.8 12.0 17.9 12.9 13.3 24.9 47.1 15.0 14.6 14.1 13.1 22.1 23.8 23.7 19.8 18.7 13.8 19.1 21.8 10.4 21.7 18.0 12.1 16.6 15.5 16.4 13.5 18.3 20.2 43.5 13.1 17.8 22.4 8.9 19.8 18.4 16.0 15.2 27.8 74.4 62.8 56.6 63.7 42.5 37.6 38.6 57.8 68.6 67.4 127.9 102.0 61.4 74.5 51.5 92.3 86.5 87.0 56.5 111.9 46.3 50.8 74.3 56.5 62.2 38.9 71.8 39.6 34.4 36.4 81.8 37.9 37.5 50.3 58.0 98.2 65.8 97.7 38.6 53.3 61.9 81.9 200.5 38.1 63.6 32.6 168.3 70.0 40.4 20.2 44.8 62.0 102.2 29.4 65.6 106.5 50.8 32.0 43.5 50.6 102.5 35.1 46.6 88.0 80.3 26.7 71.4 84.4 1.2 30.0 5.4 25.1 34.5 29.1 37.2 25.5 25.7 34.2 31.3 29.7 26.2 2.6 29.1 39.9 33.1 22.5 27.6 12.7 14.3 13.9 16.4 12.9 13.3 14.1 13.1 13.8 13.5 13.1 15.2 11.9 12.8 11.6 12.4 21.0 10.5 23.3 49.6 26.2 14.7 18.3 16.3 6.9 20.0 35.2 20.2 18.8 53.8 9.1 7.0 5.9 24.4 18.9 11.0 16.9 17.2 7.8 9.9 21.3 25.4 59.5 19.4 11.7 13.8 11.4 36.4 9.3 40.2 31.4 16.8 18.0 15.9 32.6 17.0 10.8 14.0 18.0 15.3 26.6 12.2 12.3 8.2 21.6 13.0 20.7 17.7 6.4 15.8 43.1 16.9 7.7 15.8 21.7 13.5 0.0 14.2 19.6 105.0 37.8 20.9 8.9 32.7 15.2 16.9 16.8 15.2 ALPK2 HAK ENSG00000198796 "Alpha kinase 2" Q86TB3 18 58481247-58629091 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "heart muscle: 41.9;skeletal muscle: 38.3;tongue: 33.2" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 120.4;Cone photoreceptor cells: 47.9;Early spermatids: 15.9;Late spermatids: 24.3;monocytes: 18.1" "Cancer enriched" "Detected in some" 6 "renal cancer: 7.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 51.2;BJ hTERT+: 31.0;fHDF/TERT166: 46.6;U-138 MG: 25.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA027377, HPA027976, HPA028084, HPA029801" Uncertain Approved Cytosol NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" Cytosol "HPA027377: AB_10600635, HPA027976: AB_10611246, HPA028084: AB_10601996, HPA029801: AB_10602006" "unprognostic (7.35e-2)" "unprognostic (4.91e-2)" "unprognostic (1.64e-1)" "unprognostic (4.60e-3)" "unprognostic (2.64e-1)" "unprognostic (8.27e-2)" "unprognostic (1.22e-1)" "unprognostic (1.41e-1)" "unprognostic (3.44e-1)" "unprognostic (1.06e-1)" "unprognostic (5.13e-2)" "unprognostic (1.33e-2)" "prognostic unfavorable (8.20e-5)" "unprognostic (5.27e-3)" "unprognostic (2.50e-1)" "unprognostic (4.73e-2)" "unprognostic (3.20e-2)" 0.8 0.0 0.0 2.1 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.8 0.3 0.0 0.9 41.9 0.4 0.0 9.2 4.5 0.1 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.2 2.1 0.3 0.0 38.3 0.5 1.0 0.1 0.0 0.5 1.7 1.1 0.0 3.5 0.0 33.2 4.4 1.5 0.0 0.0 0.0 13.7 0.9 0.0 0.4 3.4 0.3 51.2 31.0 21.2 18.1 3.4 0.0 0.0 5.2 46.6 2.9 0.0 0.0 0.0 21.5 11.5 0.0 0.0 4.4 1.8 2.7 0.0 0.0 3.0 0.0 6.4 0.2 0.7 0.0 0.0 0.0 0.4 13.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 11.1 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 8.3 0.0 0.0 0.0 25.3 11.2 3.5 8.7 20.9 19.2 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.7 0.1 0.0 0.0 0.0 0.2 0.1 4.8 120.4 0.0 0.0 0.0 47.9 0.0 0.1 0.0 1.9 1.5 15.9 0.0 2.3 0.9 0.0 0.0 1.0 0.7 0.0 8.9 0.0 0.1 0.0 4.0 0.4 3.0 0.7 1.7 0.7 0.0 0.0 0.3 3.0 24.3 0.3 2.4 0.0 0.0 18.1 2.6 0.0 0.0 0.8 0.2 2.3 0.0 0.6 0.0 0.3 13.6 0.0 0.9 0.0 3.8 1.7 1.1 0.1 0.0 0.9 0.1 0.3 0.0 0.0 0.0 ALPL "HOPS, TNALP, TNAP, TNSALP" ENSG00000162551 "Alkaline phosphatase, biomineralization associated" P05186 1 21509397-21578410 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Biomineralization Hydrolase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 60.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 92.0;Breast myoepithelial cells: 32.4;Glandular and luminal cells: 43.3;Hepatic stellate cells: 40.7;Hepatocytes: 30.1;Proximal tubular cells: 43.9;Rod photoreceptor cells: 34.2" "Cancer enhanced" "Detected in all" "testis cancer: 199.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 90 "neutrophil: 379.1" "Lineage enriched" "Detected in many" 139 "granulocytes: 379.1" "Cell line enhanced" "Detected in many" "HSkMC: 176.9;hTEC/SVTERT24-B: 141.2;LHCN-M2: 103.7;NTERA-2: 41.2;SCLC-21H: 88.2;SuSa: 48.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007105, HPA008765, CAB020829" Enhanced Approved Cytosol "Intracellular and membrane" NA NA 13000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 11: Alveolar cells - Smell perception" Cytosol "CAB020829: , HPA007105: AB_1078137, HPA008765: AB_1078138" "unprognostic (3.89e-2)" "unprognostic (1.27e-1)" "unprognostic (5.57e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (7.57e-4)" "unprognostic (3.05e-3)" "unprognostic (6.50e-3)" "unprognostic (1.01e-1)" "prognostic unfavorable (7.08e-4)" "unprognostic (1.17e-2)" "unprognostic (2.48e-3)" "unprognostic (1.74e-1)" "unprognostic (7.28e-2)" "unprognostic (1.73e-2)" "unprognostic (2.27e-1)" "unprognostic (9.70e-3)" "unprognostic (2.58e-1)" 24.7 60.7 19.5 27.9 16.7 4.2 22.9 18.0 25.8 3.4 26.0 5.0 2.6 5.8 1.3 4.1 10.4 3.9 16.4 17.8 18.8 45.7 56.3 54.9 6.4 21.7 17.7 2.8 3.9 3.3 9.3 3.1 22.4 7.1 1.5 18.8 6.4 9.2 1.1 4.2 7.5 3.5 18.2 45.5 4.7 4.2 21.3 1.5 8.6 5.7 5.9 9.7 3.3 17.3 0.0 0.2 5.2 0.2 0.8 6.6 11.4 0.4 2.4 0.9 1.5 1.0 0.0 2.4 7.7 0.0 0.1 0.1 31.3 0.2 0.6 0.0 2.1 0.0 3.5 3.9 1.8 0.0 0.7 176.9 0.0 141.2 0.5 0.0 0.0 0.0 0.2 0.0 103.7 0.0 0.1 0.0 41.2 0.2 0.0 0.0 3.8 0.2 0.1 0.0 88.2 1.2 0.0 0.1 0.3 48.1 0.2 0.0 0.0 5.2 4.3 0.1 0.0 0.3 0.0 0.1 0.9 0.0 0.8 0.0 0.0 4.2 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.5 0.0 0.0 379.1 0.0 0.0 0.0 0.0 0.1 19.5 16.7 18.0 25.8 17.8 18.8 21.7 17.7 22.4 18.2 21.3 17.3 25.9 3.2 92.0 0.3 3.8 0.1 0.6 8.2 0.6 2.5 6.6 32.4 2.1 2.8 17.6 0.0 0.0 0.1 0.1 0.0 7.9 0.0 1.4 15.0 2.2 26.5 0.0 5.7 0.9 0.0 0.3 6.8 0.0 43.3 7.6 10.6 40.7 30.1 0.1 1.7 0.3 0.0 12.2 1.6 0.3 8.5 0.3 1.0 0.0 18.7 0.0 6.0 0.0 6.0 0.2 0.0 0.0 0.0 0.3 1.7 0.0 43.9 3.6 34.2 0.0 0.3 5.1 0.4 14.0 0.2 0.4 1.5 1.0 8.0 0.0 0.3 AMBP "EDC1, HCP, HI30, IATIL, ITI, ITIL, ITILC, UTI" ENSG00000106927 "Alpha-1-microglobulin/bikunin precursor" P02760 9 114060127-114078328 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Host-virus interaction" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 68 "liver: 10947.9" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 10517.4" "Cancer enriched" "Detected in many" 115 "liver cancer: 2620.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 173 "Hep G2: 1398.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA001497, CAB069436, HPA075585" Approved Approved "Golgi apparatus,Vesicles,Cytosol" "Secreted to blood" NA NA 47000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Vesicles "Golgi apparatus, Cytosol" "CAB069436: AB_1611916, HPA001497: AB_1078144, HPA075585: " "unprognostic (6.92e-2)" "unprognostic (3.61e-1)" "unprognostic (4.95e-3)" "prognostic favorable (1.20e-4)" "unprognostic (9.79e-2)" "unprognostic (2.90e-1)" "unprognostic (1.04e-3)" "unprognostic (7.59e-2)" "unprognostic (2.83e-2)" "unprognostic (2.04e-1)" "unprognostic (2.14e-1)" "unprognostic (7.84e-2)" "unprognostic (4.36e-2)" "unprognostic (2.89e-3)" "unprognostic (4.66e-2)" "unprognostic (2.97e-3)" "unprognostic (9.45e-3)" 0.7 0.2 0.1 0.0 0.1 0.0 6.4 0.3 0.4 0.2 0.3 0.3 2.3 0.1 0.4 0.3 0.4 160.4 0.5 0.1 0.1 11.0 10947.9 0.3 0.0 0.1 0.1 0.2 125.3 0.0 0.2 0.4 0.1 0.2 0.5 0.2 0.1 0.0 0.2 0.3 0.7 0.0 0.1 3.1 2.6 1.0 0.1 0.1 0.4 0.0 0.2 0.1 0.2 0.0 0.0 6.7 0.1 0.0 0.2 0.1 0.0 0.0 0.5 0.0 0.0 1.8 0.0 1.8 2.1 0.2 0.9 0.5 0.0 0.0 0.0 3.2 0.0 3.0 1.0 1398.1 0.0 5.5 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.3 0.0 0.1 0.1 0.3 0.0 0.9 3.1 0.0 0.2 8.1 0.4 5.9 0.6 1.7 0.0 2.8 1.1 0.0 0.1 0.0 0.2 1.0 0.0 0.8 0.0 0.4 1.0 0.3 1.5 0.0 1.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.4 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 1.5 0.0 19.1 1.5 0.6 0.0 2.2 0.0 1.9 0.4 0.2 2585.0 0.6 1.8 0.0 0.1 0.0 0.6 3.9 216.5 30.4 0.2 0.1 10.0 2.4 219.2 0.1 28.2 0.8 0.1 0.0 1.0 0.0 0.0 181.3 10517.4 0.7 0.0 0.1 1.6 0.0 243.7 0.5 59.4 0.6 0.2 0.0 0.0 3.6 0.0 0.0 0.0 0.0 14.9 1.7 0.0 0.0 0.6 0.6 13.7 0.0 0.0 0.0 0.0 0.5 0.6 0.2 1.1 0.4 1.4 14.3 0.0 1.2 0.3 AMN1 ENSG00000151743 "Antagonist of mitotic exit network 1 homolog" Q8IY45 12 31671142-31729121 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 56.7" "Cell type enhanced" "Detected in many" "Early spermatids: 384.0;Late spermatids: 156.1;Spermatocytes: 232.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 51.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046157, HPA062290" Approved Approved Centrosome NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 77: Retina - Visual perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 66: Spermatocytes - Spermatogenesis" Centrosome "HPA046157: AB_10965846, HPA062290: AB_2684739" "unprognostic (2.11e-2)" "unprognostic (2.52e-1)" "unprognostic (3.36e-1)" "unprognostic (2.60e-1)" "unprognostic (2.80e-1)" "unprognostic (5.93e-2)" "unprognostic (8.60e-3)" "unprognostic (4.08e-2)" "unprognostic (6.48e-2)" "unprognostic (3.01e-2)" "unprognostic (1.39e-1)" "unprognostic (7.28e-2)" "unprognostic (2.48e-1)" "unprognostic (4.74e-2)" "unprognostic (1.38e-1)" "unprognostic (1.25e-1)" "unprognostic (1.30e-1)" 6.2 10.8 28.1 6.9 29.1 3.4 9.6 25.2 36.4 9.8 18.1 6.0 4.0 11.6 8.4 6.2 18.7 7.5 11.7 30.5 26.9 12.0 6.2 6.9 12.8 25.1 25.1 17.2 8.7 13.7 12.5 5.6 24.8 9.3 4.3 46.0 6.8 7.7 18.4 6.2 6.0 7.5 25.7 10.2 9.4 56.7 26.5 19.5 8.5 20.0 10.2 8.9 6.8 33.1 5.4 11.6 8.5 0.7 8.5 10.8 5.2 5.7 8.2 3.7 7.1 6.0 19.8 2.6 11.9 4.8 28.1 2.8 4.3 6.4 7.6 4.6 5.4 9.7 3.9 8.7 15.4 5.0 4.8 7.1 10.5 6.3 8.9 28.4 21.4 13.9 8.4 8.0 14.3 3.3 2.9 4.0 12.5 11.2 5.1 4.2 14.7 4.5 8.7 11.9 14.7 11.2 7.3 1.5 11.7 19.3 16.9 5.6 11.5 6.1 5.1 5.2 9.9 9.1 9.5 9.0 8.2 4.5 11.9 8.2 5.0 6.4 7.4 3.7 7.5 22.1 7.7 7.9 4.0 19.3 16.9 10.5 51.8 9.4 3.2 12.4 12.8 5.9 28.1 29.1 25.2 36.4 30.5 26.9 25.1 25.1 24.8 25.7 26.5 33.1 13.2 6.4 2.7 25.5 25.7 9.3 25.6 35.3 12.5 11.7 10.5 6.7 4.0 7.2 22.3 16.5 27.1 7.1 3.1 2.1 27.4 10.5 384.0 20.0 4.7 11.5 14.4 1.7 48.6 7.2 5.3 7.7 7.1 12.1 7.6 8.1 11.4 3.2 9.0 30.3 58.5 1.9 42.7 6.0 6.8 156.1 10.2 7.7 16.0 13.1 4.1 15.9 11.3 22.1 67.3 11.1 1.0 13.5 5.4 16.9 2.0 11.4 22.9 43.2 0.0 6.1 11.2 232.9 31.1 6.9 12.6 7.3 9.5 10.8 2.1 32.3 AMZ1 KIAA1950 ENSG00000174945 "Archaelysin family metallopeptidase 1" Q400G9 7 2679522-2775500 "Enzymes, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 8 "brain: 7.5" "Cell type enriched" "Detected in some" 5 "Oligodendrocyte precursor cells: 104.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "BEWO: 7.0;MCF7: 7.5;SK-BR-3: 5.2;T-47d: 27.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020233 Uncertain NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 65: Brain - Ion transport" "Cluster 6: T47d - Mammary gland" "Cluster 68: Oligodendrocytes - Mixed function" "HPA020233: AB_1844818" "unprognostic (9.08e-3)" "unprognostic (1.66e-1)" "unprognostic (3.23e-3)" "unprognostic (1.81e-1)" "unprognostic (5.72e-2)" "unprognostic (7.79e-2)" "unprognostic (2.02e-2)" "unprognostic (3.42e-1)" "unprognostic (1.98e-1)" "unprognostic (7.16e-3)" "unprognostic (1.08e-1)" "unprognostic (1.21e-1)" "unprognostic (3.64e-9)" "unprognostic (1.60e-3)" "unprognostic (1.60e-1)" "unprognostic (1.44e-1)" "unprognostic (1.13e-1)" 0.0 0.0 7.4 0.2 7.5 0.4 0.1 3.4 5.1 0.9 0.0 0.1 0.1 0.8 0.0 0.0 0.3 0.1 0.1 3.6 1.9 0.0 0.8 0.5 0.2 3.6 3.7 0.2 0.1 0.0 0.6 0.8 2.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.7 0.6 0.4 0.0 0.6 6.1 0.0 0.0 0.0 0.3 0.1 0.3 1.7 0.0 0.0 0.0 0.0 0.0 0.0 7.0 2.3 3.4 1.6 2.2 0.0 1.0 0.6 0.2 2.2 0.2 0.0 0.0 0.0 1.6 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 1.5 0.0 7.5 0.0 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.1 5.2 0.0 0.1 27.7 0.0 0.0 0.1 0.1 0.1 0.1 1.0 0.2 0.0 0.6 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 7.4 7.5 3.4 5.1 3.6 1.9 3.6 3.7 2.1 0.6 6.1 1.7 0.1 0.0 0.5 14.4 0.9 0.0 0.1 0.0 0.0 0.8 0.3 0.3 3.3 0.0 0.0 0.0 4.2 0.3 1.6 0.0 0.0 0.0 18.8 0.5 1.6 0.4 0.0 0.0 6.1 0.0 9.8 0.3 0.0 0.3 0.0 0.0 0.0 0.0 1.8 0.0 10.6 0.2 0.0 0.0 1.9 9.9 0.0 1.7 1.8 5.6 0.0 0.0 0.0 104.5 20.7 0.4 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.7 0.0 0.2 0.4 0.0 0.3 0.0 0.1 0.1 0.8 0.0 0.0 0.1 ANG "RAA1, RNASE5" ENSG00000214274 Angiogenin P03950 14 20684177-20698971 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Angiogenesis, Differentiation, Stress response" "Developmental protein, DNA-binding, Endonuclease, Hydrolase, Nuclease, Protein synthesis inhibitor" "Amyotrophic lateral sclerosis, Cancer-related genes, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 52 "liver: 3018.1" "Cell type enriched" "Detected in many" 24 "Hepatocytes: 4816.3" "Cancer enriched" "Detected in all" 17 "liver cancer: 279.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 24.5;myeloid DC: 14.5" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Hep G2: 152.2;OE19: 116.1" "Low region specificity" "Detected in all" HPA055896 Approved "Nucleoli,Nucleoli rim,Mitotic chromosome,Actin filaments" "Secreted to blood" Yes No 308000000 410000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Nucleoli, Nucleoli rim, Mitotic chromosome" "Actin filaments" "HPA055896: " "unprognostic (2.50e-2)" "unprognostic (1.82e-1)" "unprognostic (9.77e-2)" "prognostic favorable (6.85e-4)" "unprognostic (5.71e-3)" "unprognostic (6.99e-2)" "prognostic favorable (7.83e-5)" "unprognostic (1.16e-1)" "unprognostic (3.20e-3)" "unprognostic (9.19e-3)" "unprognostic (1.31e-1)" "unprognostic (3.69e-1)" "unprognostic (6.65e-2)" "unprognostic (1.03e-1)" "unprognostic (3.39e-1)" "unprognostic (2.00e-1)" "unprognostic (3.09e-1)" 37.6 3.0 3.6 6.0 3.5 1.0 37.8 3.5 4.9 38.2 5.6 32.6 23.2 23.4 17.9 9.8 30.5 28.5 16.9 3.6 4.9 18.4 3018.1 18.5 3.5 4.5 4.2 58.1 30.8 5.3 5.0 3.8 4.3 32.7 45.7 2.2 52.6 13.3 6.2 27.4 27.1 10.4 4.5 7.4 58.2 10.2 3.7 1.5 8.8 10.5 4.1 24.8 31.4 4.8 3.7 9.9 2.3 0.0 23.9 27.8 0.3 4.8 8.8 1.1 4.0 5.9 5.1 0.4 1.5 12.0 8.0 3.8 2.8 3.1 1.3 18.4 3.8 0.9 5.1 152.2 5.0 4.0 0.5 22.2 2.5 1.5 5.1 11.8 5.7 4.2 0.2 27.0 3.5 0.7 0.9 1.2 0.7 116.1 10.7 0.7 3.9 11.3 2.3 2.9 0.0 0.4 4.6 1.7 6.5 5.1 4.0 0.7 6.0 1.9 2.8 1.7 0.7 5.9 4.8 0.5 3.2 2.0 5.0 0.0 24.5 0.0 0.6 2.9 0.4 5.8 1.2 1.1 14.5 4.9 0.3 0.2 0.4 0.0 0.1 2.3 0.8 7.1 3.6 3.5 3.5 4.9 3.6 4.9 4.5 4.2 4.3 4.5 3.7 4.8 9.7 28.9 17.7 0.0 9.7 27.1 43.3 39.2 14.2 0.1 33.8 24.8 0.8 194.5 24.6 11.0 0.0 1.6 0.7 32.5 11.7 40.0 1.0 6.2 9.7 11.0 71.0 27.8 0.0 31.6 5.3 48.8 56.1 24.9 0.0 10.7 62.4 4816.3 15.9 0.0 0.0 171.9 12.2 95.9 18.7 2.9 71.1 13.8 23.2 0.0 4.9 10.1 0.0 0.0 0.0 21.6 33.3 24.0 11.7 43.7 91.3 61.2 76.5 0.6 13.1 29.7 17.7 1.0 1.3 9.4 52.4 9.3 5.6 0.5 51.6 39.2 ANGPT2 Ang2 ENSG00000091879 "Angiopoietin 2" O15123 8 6499632-6563409 "Cancer-related genes, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 81.7;Endothelial cells: 182.2;Smooth muscle cells: 79.8" "Cancer enhanced" "Detected in all" "renal cancer: 12.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.7" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 8 "HMC-1: 17.9;HSkMC: 39.9;HUVEC TERT2: 62.6;WM-115: 22.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB011437, CAB017626" Approved "Secreted to blood" NA NA 3780000 110000 "Cluster 10: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "CAB011437: , CAB017626: AB_1118956" "unprognostic (1.28e-1)" "prognostic unfavorable (7.99e-5)" "unprognostic (1.93e-2)" "unprognostic (1.23e-1)" "unprognostic (4.85e-1)" "unprognostic (4.86e-2)" "prognostic unfavorable (6.36e-5)" "unprognostic (1.66e-3)" "prognostic unfavorable (4.48e-4)" "unprognostic (2.94e-3)" "unprognostic (6.19e-3)" "unprognostic (1.38e-1)" "prognostic unfavorable (1.52e-7)" "prognostic unfavorable (3.87e-4)" "unprognostic (1.12e-1)" "unprognostic (1.46e-2)" "unprognostic (6.44e-2)" 15.7 0.5 5.6 3.8 5.0 0.4 9.9 6.3 9.0 6.2 2.6 2.9 1.2 4.3 1.1 2.2 4.2 4.9 7.3 4.9 6.3 5.4 2.7 4.6 6.8 12.3 5.8 2.5 0.8 2.3 0.8 11.3 12.3 3.3 1.8 1.6 2.5 2.7 4.0 3.1 2.5 6.8 7.7 0.5 1.8 0.9 7.6 6.4 8.2 2.0 2.8 10.6 3.2 7.5 0.1 0.2 0.3 0.1 0.4 0.3 0.3 0.0 0.0 0.0 0.0 0.3 0.2 0.2 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.1 0.1 4.7 0.4 0.1 0.9 0.0 17.9 39.9 0.0 0.0 0.0 0.1 62.6 0.1 0.1 0.4 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.5 0.8 0.0 0.0 0.1 0.3 0.1 0.1 1.3 0.2 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.1 22.7 1.7 0.2 0.2 0.2 0.1 0.2 0.2 0.2 0.2 0.0 0.4 0.2 0.3 0.2 0.2 0.1 0.3 0.1 0.1 5.6 5.0 6.3 9.0 4.9 6.3 12.3 5.8 12.3 7.7 7.6 7.5 81.7 9.6 0.0 5.2 7.8 8.2 2.7 2.5 1.8 9.3 1.5 1.4 2.8 2.8 1.6 0.0 29.2 1.8 3.6 0.6 0.0 1.3 3.2 4.2 5.4 182.2 13.8 1.3 17.0 0.5 1.5 6.3 1.5 5.9 4.5 2.0 30.4 0.9 0.6 38.7 16.1 1.7 0.0 2.5 10.9 5.0 43.5 2.7 16.0 26.2 2.4 2.9 7.2 24.6 11.3 1.3 1.2 3.8 0.9 9.9 2.6 1.0 1.4 12.5 0.0 8.1 79.8 1.6 1.6 0.3 8.0 30.6 5.5 2.9 1.3 4.7 ANKRD13A "ANKRD13, NY-REN-25" ENSG00000076513 "Ankyrin repeat domain 13A" Q8IZ07 12 109999186-110039763 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 160.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "fHDF/TERT166: 205.4;HBF TERT88: 200.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039488, HPA043218" Enhanced Supported "Plasma membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 57: B-cells - Immune response" "Plasma membrane" "HPA039488: AB_10673612, HPA043218: AB_2678367" "unprognostic (1.54e-1)" "unprognostic (3.94e-3)" "unprognostic (5.81e-1)" "unprognostic (1.62e-2)" "unprognostic (1.05e-1)" "prognostic favorable (7.70e-6)" "unprognostic (5.68e-2)" "unprognostic (1.31e-2)" "unprognostic (2.19e-1)" "prognostic unfavorable (6.77e-4)" "unprognostic (9.71e-3)" "unprognostic (1.67e-1)" "unprognostic (2.67e-2)" "unprognostic (2.57e-1)" "unprognostic (2.13e-2)" "unprognostic (1.08e-1)" "unprognostic (5.29e-2)" 13.2 10.9 6.3 36.5 10.0 36.0 16.4 8.8 8.1 14.1 6.1 21.8 14.3 11.9 6.6 31.7 12.3 22.9 10.7 7.1 7.4 17.6 15.3 26.9 54.0 8.4 8.7 16.3 12.3 17.4 4.6 24.4 9.0 17.9 22.4 8.7 27.5 24.6 6.9 22.6 17.6 24.4 7.5 32.8 17.1 60.9 8.4 27.9 28.2 8.7 66.7 25.9 13.2 15.0 163.7 7.3 16.9 15.6 25.4 25.1 20.8 160.9 150.5 149.8 79.3 21.2 10.3 107.8 12.4 205.4 18.7 19.0 21.7 24.0 200.3 122.3 19.2 39.9 15.6 17.4 22.2 46.8 46.2 21.9 24.9 63.8 36.5 37.3 23.0 24.9 31.6 17.2 66.5 5.8 41.3 19.5 9.3 11.7 34.1 35.8 47.3 42.7 21.2 20.7 34.7 16.5 29.6 57.0 19.5 11.4 26.0 38.5 29.2 111.6 20.0 62.2 87.4 36.8 23.3 144.1 54.3 31.7 16.5 1.5 1.2 5.6 0.5 2.5 1.5 2.0 1.3 0.6 1.5 1.2 0.7 1.0 3.5 0.9 1.1 1.0 0.6 0.7 6.3 10.0 8.8 8.1 7.1 7.4 8.4 8.7 9.0 7.5 8.4 15.0 15.7 48.1 32.5 13.4 75.5 29.3 18.7 11.0 15.4 24.4 23.1 16.9 13.0 28.6 30.5 57.0 14.6 16.9 31.2 30.3 21.5 29.2 104.7 22.0 12.3 14.9 18.7 19.4 15.9 17.6 21.0 15.5 16.3 29.5 13.3 18.5 15.7 17.3 15.4 25.2 26.9 9.4 4.1 37.1 26.9 160.4 11.8 33.7 14.2 16.9 34.2 9.7 21.6 17.6 46.0 20.8 12.5 21.8 33.0 16.2 16.0 9.8 37.6 14.2 32.9 50.3 18.0 71.1 15.0 23.9 37.8 37.6 31.8 16.9 17.0 25.7 ANKRD27 "DKFZp434L0718, FLJ00040, VARP" ENSG00000105186 "Ankyrin repeat domain 27" Q96NW4 19 32597006-32676597 "Predicted intracellular proteins" "Protein transport, Transport" "GTPase activation, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEL: 137.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042769 Approved Supported Vesicles,Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 36: HEL - Hemostasis" "Cluster 59: Non-specific - Transcription" Vesicles Cytosol "HPA042769: AB_10796584" "unprognostic (2.16e-3)" "unprognostic (6.04e-2)" "unprognostic (1.01e-1)" "prognostic unfavorable (8.68e-4)" "unprognostic (1.63e-1)" "unprognostic (1.21e-2)" "prognostic unfavorable (1.21e-5)" "unprognostic (9.02e-2)" "unprognostic (1.07e-1)" "unprognostic (1.61e-2)" "unprognostic (2.90e-2)" "unprognostic (6.22e-3)" "unprognostic (3.74e-2)" "unprognostic (2.14e-1)" "unprognostic (4.94e-2)" "unprognostic (4.07e-1)" "unprognostic (2.26e-2)" 8.9 7.4 10.8 8.9 12.9 10.4 8.7 12.1 12.6 10.3 21.5 17.2 7.6 10.0 8.8 14.3 8.0 7.7 9.6 11.8 9.8 9.7 4.4 10.3 11.1 12.0 12.9 8.3 7.2 9.3 6.8 13.6 12.4 12.3 11.9 11.7 9.7 13.5 20.7 12.4 10.7 11.6 8.9 9.0 11.0 17.3 12.1 16.7 13.3 10.8 11.5 16.9 11.1 11.8 32.0 36.0 11.5 20.8 23.5 18.0 28.1 18.0 18.0 19.4 25.4 28.8 19.0 34.7 16.5 23.0 20.4 19.4 29.6 22.3 32.0 47.3 15.1 137.9 13.7 23.9 29.4 53.5 47.6 13.1 28.8 20.9 33.8 13.5 19.7 25.3 37.5 76.3 15.1 31.5 20.8 46.2 6.0 40.2 13.8 30.6 15.6 12.7 15.6 30.5 21.3 8.6 17.6 29.6 21.0 15.2 12.4 25.7 18.5 21.1 22.4 19.6 28.0 19.7 12.7 23.8 21.0 51.8 13.8 36.5 11.1 28.5 13.9 15.7 17.5 7.5 14.3 15.6 12.6 6.9 10.9 11.7 9.0 30.6 13.3 6.2 13.2 13.3 10.8 12.9 12.1 12.6 11.8 9.8 12.0 12.9 12.4 8.9 12.1 11.8 6.8 16.0 9.4 18.3 10.0 15.6 5.5 5.6 14.2 9.4 9.0 5.1 9.2 7.2 5.7 9.2 20.9 14.9 9.7 9.3 0.0 3.3 5.1 7.5 9.4 7.1 9.1 26.5 35.5 5.9 10.6 7.6 5.6 11.6 12.0 10.1 4.6 4.8 8.4 11.8 16.3 9.6 8.2 12.0 12.1 16.2 10.8 8.7 16.0 12.2 6.0 5.8 9.2 11.1 18.7 7.1 10.3 9.4 8.0 10.0 10.8 7.7 7.1 14.7 0.0 6.8 9.3 4.1 17.1 14.7 15.5 15.2 14.0 7.2 8.9 8.4 ANKRD28 "CFAP79, FAP79, KIAA0379, PITK, PP6-ARS-A, PPP1R65" ENSG00000206560 "Ankyrin repeat domain 28" O15084 3 15667236-15859771 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Melanocytes: 282.8;Oligodendrocyte precursor cells: 364.4;Oligodendrocytes: 284.4;Plasma cells: 733.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 27 "basophil: 17.0" "Lineage enriched" "Detected in single" 27 "granulocytes: 17.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (4.72e-2)" "unprognostic (8.71e-2)" "unprognostic (1.91e-3)" "unprognostic (1.48e-2)" "unprognostic (9.73e-2)" "unprognostic (4.29e-3)" "unprognostic (1.38e-1)" "unprognostic (1.27e-1)" "unprognostic (8.04e-2)" "unprognostic (2.04e-1)" "unprognostic (5.39e-3)" "unprognostic (7.71e-2)" "prognostic favorable (2.85e-4)" "unprognostic (2.32e-1)" "unprognostic (1.24e-1)" "unprognostic (4.43e-2)" "unprognostic (1.06e-1)" 13.2 7.0 8.1 5.7 9.1 11.6 13.4 12.3 12.6 11.3 6.8 10.0 9.6 9.0 27.7 7.8 7.6 9.9 5.8 8.1 8.4 10.3 13.5 9.0 5.8 9.5 7.9 11.3 13.8 15.7 5.6 6.4 8.9 6.8 9.7 14.0 8.2 7.8 23.9 10.7 7.8 6.3 7.9 7.1 10.7 11.9 7.5 10.3 13.5 20.1 8.9 9.1 10.1 10.7 16.3 10.7 11.6 7.9 38.4 31.7 37.7 20.6 28.9 26.0 29.8 6.5 16.3 31.6 7.0 20.8 20.4 6.5 9.6 17.0 26.4 6.9 13.5 15.0 14.5 10.7 62.7 23.4 10.0 46.4 11.7 24.6 25.6 32.4 27.5 17.4 11.5 41.4 67.6 11.0 19.7 15.1 23.8 10.8 8.8 17.1 21.8 26.9 24.9 16.2 5.9 10.5 15.3 15.4 63.9 10.4 9.2 18.3 21.8 32.9 20.2 25.1 20.3 25.2 31.2 18.8 24.6 16.8 25.5 17.0 0.0 0.0 0.3 0.0 0.4 0.2 0.6 0.3 0.1 0.2 0.2 0.3 0.1 0.2 0.0 0.3 0.2 0.2 8.1 9.1 12.3 12.6 8.1 8.4 9.5 7.9 8.9 7.9 7.5 10.7 39.2 32.1 51.2 63.6 69.9 42.6 20.8 17.0 17.6 27.9 37.7 16.0 18.9 18.6 39.9 7.3 139.7 8.9 71.6 19.5 9.8 14.4 95.5 25.5 55.0 61.4 19.8 37.6 175.4 20.7 9.3 73.4 36.7 42.0 196.7 17.3 21.0 45.1 41.0 52.2 144.5 18.1 22.4 59.7 181.3 92.2 34.8 87.5 282.8 47.8 16.7 43.2 19.6 364.4 284.4 14.8 14.8 10.9 733.4 35.1 12.7 11.3 45.2 41.3 0.0 45.6 29.3 24.4 10.5 25.3 33.5 3.4 195.5 10.2 20.5 21.5 ANKRD30B NY-BR-1.1 ENSG00000180777 "Ankyrin repeat domain 30B" Q9BXX2 18 14728272-14854038 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 7 "testis: 8.2" "Group enriched" "Detected in some" 8 "Early spermatids: 13.1;Excitatory neurons: 32.6;Inhibitory neurons: 39.3;Late spermatids: 13.9;Spermatocytes: 23.7" "Cancer enriched" "Detected in single" 5 "breast cancer: 2.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "U-2197: 63.1" "HPA060455, HPA071849" Uncertain Uncertain Nucleoli NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 18: U-2197 - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoli "HPA060455: AB_2684282, HPA071849: " "unprognostic (1.53e-1)" "unprognostic (1.50e-1)" "unprognostic (1.01e-2)" "unprognostic (1.65e-1)" "unprognostic (1.86e-1)" "unprognostic (9.74e-2)" "unprognostic (2.84e-1)" "unprognostic (1.55e-9)" "unprognostic (1.38e-2)" "unprognostic (1.53e-1)" "unprognostic (7.98e-2)" 0.1 0.1 0.2 0.0 0.4 0.0 1.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 8.2 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.1 13.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 1.7 0.0 1.1 4.4 0.3 63.1 0.0 6.7 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.6 0.4 0.4 0.4 0.1 0.1 0.2 0.1 0.5 0.0 0.0 0.0 1.6 0.1 0.0 0.4 0.0 0.0 0.0 2.8 1.0 1.9 0.0 0.0 0.0 0.0 0.5 0.0 0.5 1.9 0.0 13.1 0.7 0.1 0.2 1.8 0.0 32.6 0.0 0.4 0.1 0.0 1.8 0.0 0.1 0.0 0.1 0.1 0.0 39.3 1.6 0.0 0.3 0.0 13.9 0.9 0.2 0.0 1.0 0.0 0.0 0.0 2.5 1.1 0.0 0.5 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.1 23.7 1.7 0.0 0.3 0.5 0.1 0.0 1.1 0.3 ANKRD30BL "ANKRD30BP3, NCRNA00164" ENSG00000163046 "Ankyrin repeat domain 30B like" A7E2S9 2 132147591-132257969 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 21 "testis: 3.4" "Group enriched" "Detected in some" 4 "Excitatory neurons: 239.7;Inhibitory neurons: 229.8;Oligodendrocyte precursor cells: 73.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 21 "REH: 2.0" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 14: REH - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (1.67e-1)" "unprognostic (1.42e-1)" "unprognostic (5.57e-2)" "unprognostic (2.15e-1)" "unprognostic (2.99e-1)" "unprognostic (2.17e-1)" "unprognostic (1.42e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.2 0.1 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.3 0.1 0.0 0.0 0.0 239.7 0.0 0.0 0.0 0.0 0.4 0.0 1.2 0.0 0.0 0.0 0.0 229.8 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 3.7 0.0 0.2 0.0 73.9 6.9 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 42.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 ANKRD45 "CT117, FLJ45235" ENSG00000183831 "Ankyrin repeat domain 45" Q5TZF3 1 173608336-173669851 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 6.7;choroid plexus: 14.3;fallopian tube: 12.7;parathyroid gland: 9.3;testis: 11.0" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 37.5;Early spermatids: 48.8;Endometrial ciliated cells: 23.7;Late spermatids: 16.8;Respiratory ciliated cells: 31.8;Spermatocytes: 54.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 5.5;BJ hTERT+: 2.0;BJ hTERT+ SV40 Large T+ RasG12V: 2.6;GAMG: 1.9;HBF TERT88: 1.9;SH-SY5Y: 5.7" "HPA031655, HPA031656, HPA031657" Enhanced Approved "Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "Plasma membrane, Centrosome" "HPA031655: AB_10610975, HPA031656: AB_10600331, HPA031657: AB_10602196" "unprognostic (1.93e-1)" "unprognostic (1.22e-1)" "unprognostic (2.21e-2)" "unprognostic (1.90e-1)" "unprognostic (1.29e-3)" "unprognostic (4.02e-1)" "unprognostic (3.57e-2)" "unprognostic (2.69e-3)" "unprognostic (4.15e-2)" "unprognostic (6.93e-2)" "unprognostic (2.45e-1)" "unprognostic (3.05e-2)" "unprognostic (4.49e-2)" "unprognostic (8.80e-3)" "unprognostic (2.91e-2)" "unprognostic (5.15e-2)" "unprognostic (1.61e-1)" 0.2 0.6 2.8 0.0 5.4 0.2 0.1 1.9 2.5 1.3 14.3 0.2 0.0 1.6 0.7 0.0 12.7 0.3 0.4 4.3 2.8 1.3 0.0 1.2 0.0 5.2 6.7 0.7 0.3 9.3 1.8 0.0 3.9 0.8 0.1 2.6 0.0 0.3 0.2 0.0 0.0 1.1 3.3 0.4 0.1 11.0 3.8 0.2 0.5 0.0 0.0 0.1 0.1 4.0 0.0 0.0 5.5 0.0 0.0 0.3 0.1 0.0 2.0 1.7 2.6 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 5.7 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 1.2 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 2.8 5.4 1.9 2.5 4.3 2.8 5.2 6.7 3.9 3.3 3.8 4.0 0.2 0.0 1.7 12.4 0.0 0.3 0.3 1.1 0.0 0.7 0.1 0.4 0.9 0.0 1.5 5.5 37.5 0.2 0.0 0.3 1.9 0.6 48.8 23.7 1.3 1.3 0.0 0.0 4.6 0.5 0.3 0.4 0.0 0.6 0.0 1.1 3.3 0.0 0.1 0.0 4.1 0.0 6.1 0.0 0.0 16.8 1.8 0.2 0.0 2.8 0.0 3.3 0.0 0.5 3.2 0.1 0.0 0.4 0.0 0.2 0.0 0.4 31.8 1.7 0.0 0.1 0.8 54.9 7.9 0.0 0.0 0.1 0.0 5.5 0.4 0.1 ANKRD53 "FLJ12056, FLJ36160" ENSG00000144031 "Ankyrin repeat domain 53" Q8N9V6 2 70978380-70985499 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 27.5" "Group enriched" "Detected in many" 21 "Early spermatids: 158.6;Late spermatids: 481.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in some" 5 "plasmacytoid DC: 7.0" "Lineage enriched" "Detected in many" 5 "dendritic cells: 7.0" "Cell line enhanced" "Detected in some" "ASC diff: 1.0;HHSteC: 1.6;HSkMC: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA049574 Approved NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "HPA049574: AB_2680819" "unprognostic (6.11e-3)" "unprognostic (6.51e-2)" "unprognostic (1.70e-3)" "unprognostic (2.68e-1)" "unprognostic (2.01e-2)" "unprognostic (6.31e-3)" "unprognostic (2.20e-1)" "unprognostic (6.35e-2)" "unprognostic (3.53e-1)" "unprognostic (1.27e-1)" "unprognostic (6.39e-3)" "unprognostic (1.83e-1)" "unprognostic (1.13e-2)" "unprognostic (1.68e-3)" "unprognostic (2.45e-1)" "unprognostic (1.00e-2)" "unprognostic (1.69e-1)" 7.5 1.7 0.3 0.6 0.2 0.3 6.1 1.5 0.5 1.8 0.0 1.9 0.7 1.8 0.4 0.7 3.0 0.7 1.3 0.3 0.2 0.8 0.6 1.3 0.3 0.8 0.4 4.1 8.2 0.3 3.2 0.3 0.2 2.0 0.2 6.1 4.5 0.6 0.4 0.8 1.7 0.6 0.3 0.8 2.0 27.5 0.1 0.1 3.1 0.3 0.3 1.6 1.6 0.2 0.0 0.0 0.1 0.1 1.0 0.4 0.1 0.1 0.4 0.4 0.4 0.2 0.0 0.0 0.0 0.8 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 1.6 0.0 0.0 1.6 0.0 0.4 0.0 0.1 0.4 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.5 0.2 0.1 0.3 0.0 0.2 0.0 0.0 0.1 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.3 0.2 1.5 0.5 0.3 0.2 0.8 0.4 0.2 0.3 0.1 0.2 1.1 0.0 0.0 0.3 1.1 0.1 1.4 0.5 4.6 1.3 0.3 1.3 0.4 1.5 0.1 0.0 2.1 0.1 1.0 0.0 0.0 1.2 158.6 4.3 0.5 0.7 0.0 0.4 0.4 0.4 1.0 1.9 1.1 2.2 0.0 0.4 1.1 0.2 0.0 1.7 1.2 0.0 0.0 0.0 0.4 481.3 3.4 0.4 0.0 0.0 0.0 4.1 0.0 1.5 0.3 0.5 0.0 3.0 11.7 0.7 0.1 1.5 0.6 15.1 6.6 2.8 1.5 1.5 1.7 0.6 0.0 0.3 0.4 0.1 0.1 0.1 ANKRD62 DKFZp779B1634 ENSG00000181626 "Ankyrin repeat domain 62" A6NC57 18 12093843-12129764 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 6 "brain: 1.1;pancreas: 1.0;testis: 1.6" "Cell type enriched" "Detected in some" 5 "Spermatocytes: 92.8" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA059835 Enhanced Uncertain "Nucleoplasm,Nuclear bodies,Actin filaments" NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Nuclear bodies" "Actin filaments" "HPA059835: AB_2684136" "unprognostic (2.45e-2)" "unprognostic (1.18e-1)" "unprognostic (2.37e-3)" "unprognostic (9.46e-2)" "unprognostic (3.01e-1)" "unprognostic (1.98e-1)" "unprognostic (6.61e-2)" "unprognostic (7.95e-2)" "unprognostic (3.27e-1)" "unprognostic (2.55e-4)" "unprognostic (1.13e-1)" "unprognostic (3.28e-2)" "unprognostic (4.52e-3)" "unprognostic (8.70e-2)" 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.4 0.0 0.6 0.0 0.7 0.0 0.0 0.4 0.1 0.0 1.3 0.3 0.1 0.4 0.3 0.0 0.0 1.7 0.4 0.1 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 2.2 0.1 0.2 0.5 0.0 0.0 16.5 1.7 0.6 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.6 0.8 2.6 0.6 0.2 0.0 1.0 0.0 0.1 1.0 1.0 0.2 0.5 1.1 0.4 0.0 0.8 0.2 0.0 0.0 0.9 0.0 1.3 0.3 92.8 15.8 0.5 1.1 0.0 0.2 0.1 0.2 0.5 ANKRD7 TSA806 ENSG00000106013 "Ankyrin repeat domain 7" Q92527 7 118214669-118496171 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 431 "testis: 860.1" "Group enriched" "Detected in some" 61 "Early spermatids: 3367.0;Late spermatids: 861.1;Spermatocytes: 3073.6" "Cancer enhanced" "Detected in some" "testis cancer: 1.9" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 4.3;JURKAT: 4.6;SCLC-21H: 7.8;U-266/70: 9.8;WM-115: 3.1" "HPA043489, HPA052941" Enhanced Nucleoplasm NA NA "Cluster 37: B-cells - Transcription" "Cluster 74: Testis - Spermatogenesis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "HPA043489: AB_10959304, HPA052941: " "unprognostic (1.29e-1)" "unprognostic (7.22e-4)" "unprognostic (3.13e-3)" "unprognostic (6.16e-2)" "unprognostic (8.49e-2)" "unprognostic (1.69e-1)" "unprognostic (5.51e-1)" "unprognostic (9.46e-2)" "unprognostic (1.44e-1)" "unprognostic (2.63e-3)" "unprognostic (1.45e-2)" "unprognostic (1.55e-2)" "unprognostic (3.35e-2)" "unprognostic (3.57e-4)" "unprognostic (3.32e-2)" 0.1 0.5 0.3 0.1 0.4 0.0 0.5 0.0 0.7 0.3 0.1 0.2 0.5 0.1 1.9 0.1 0.4 0.1 0.3 0.4 1.0 0.7 0.2 0.1 0.2 0.6 0.7 0.2 0.7 0.1 0.7 0.0 0.9 0.6 0.1 0.3 0.1 0.1 0.3 0.1 0.2 0.2 0.1 0.2 0.1 860.1 1.1 0.1 0.9 0.1 0.2 0.1 0.1 0.5 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 4.3 1.2 0.0 2.3 0.0 0.0 0.2 0.1 1.2 0.8 0.0 0.0 0.0 1.4 0.0 0.0 1.7 0.3 0.5 0.0 0.3 0.0 4.6 0.0 1.7 1.1 0.0 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 2.0 0.0 0.0 1.5 0.0 0.0 1.0 0.3 0.0 0.8 0.2 0.0 9.8 0.5 0.4 1.4 0.0 3.1 0.0 0.0 0.2 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.4 0.0 0.7 0.4 1.0 0.6 0.7 0.9 0.1 1.1 0.5 0.3 0.0 0.0 0.3 0.3 0.0 0.3 0.4 0.0 0.9 0.1 0.3 0.5 1.5 0.1 0.0 0.0 0.1 0.0 0.1 5.9 0.2 3367.0 0.5 0.3 1.6 0.0 0.4 2.8 0.2 0.1 0.2 0.0 0.0 0.0 1.2 0.4 0.0 0.1 3.3 2.8 0.0 0.0 0.0 0.0 861.1 39.4 2.7 1.8 1.0 0.0 1.8 0.0 0.0 1.0 0.1 0.0 29.3 0.1 0.1 0.0 2.0 0.2 0.0 26.3 0.2 0.2 3073.6 29.9 0.0 0.1 0.0 0.1 2.5 0.0 0.1 ANKS1A "ANKS1, KIAA0229" ENSG00000064999 "Ankyrin repeat and sterile alpha motif domain containing 1A" Q92625 6 34889255-35091406 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 94.0;Inhibitory neurons: 160.5;Microglial cells: 168.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "SCLC-21H: 58.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036768, HPA036769" Approved Approved Nucleoplasm,Cytosol NA NA 17000 "Cluster 14: Monocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm Cytosol "HPA036768: AB_10670923, HPA036769: AB_10672473" "unprognostic (3.75e-2)" "unprognostic (2.67e-1)" "unprognostic (2.59e-2)" "unprognostic (7.79e-3)" "unprognostic (5.73e-2)" "prognostic favorable (7.48e-4)" "unprognostic (1.18e-3)" "unprognostic (3.51e-3)" "unprognostic (1.62e-1)" "unprognostic (2.18e-1)" "unprognostic (1.42e-1)" "unprognostic (1.38e-2)" "prognostic favorable (8.05e-5)" "unprognostic (1.76e-1)" "unprognostic (9.71e-2)" "unprognostic (2.23e-2)" "unprognostic (7.80e-2)" 15.0 19.1 15.2 8.0 13.9 5.7 15.0 16.4 15.8 10.9 13.8 29.0 10.5 10.7 7.4 15.4 20.1 10.0 18.6 12.7 13.4 13.1 10.7 18.8 9.3 15.6 17.0 17.4 9.4 16.4 8.4 27.8 17.4 11.7 9.0 22.9 9.2 15.4 20.1 15.6 14.3 14.3 14.0 23.0 14.8 16.5 22.1 7.6 13.8 9.5 5.7 27.2 13.1 11.9 15.4 7.3 14.8 14.2 6.5 6.4 22.3 6.0 6.7 7.2 8.7 18.4 9.7 10.4 10.0 6.4 13.1 15.7 17.4 17.6 8.3 8.0 21.9 7.3 9.2 13.7 4.0 11.8 6.7 7.4 14.9 9.3 12.3 7.7 15.9 10.7 12.6 4.4 6.4 10.0 7.4 12.8 10.7 20.3 8.4 8.9 8.3 10.6 14.5 27.9 58.5 14.8 10.3 14.1 43.7 18.1 11.1 13.0 13.9 7.3 9.2 7.6 8.9 6.7 10.9 5.5 5.6 16.8 20.3 0.0 0.6 0.5 0.2 0.9 0.4 0.4 0.2 0.4 0.5 0.1 0.3 0.2 1.1 0.2 1.5 1.1 0.3 0.4 15.2 13.9 16.4 15.8 12.7 13.4 15.6 17.0 17.4 14.0 22.1 11.9 48.2 80.1 11.4 54.2 4.4 12.1 9.1 4.2 4.0 28.8 11.3 14.4 25.3 11.5 8.3 12.9 64.6 8.9 5.5 17.2 0.0 7.3 12.7 32.1 7.4 31.7 13.2 5.7 94.0 5.9 7.5 10.0 13.3 35.6 2.5 17.2 47.5 6.6 11.9 8.4 160.5 11.0 18.3 29.2 10.9 11.3 12.8 18.9 5.4 168.6 8.1 21.7 10.3 90.5 75.9 10.2 7.6 30.1 6.4 13.3 10.0 7.0 29.0 45.4 19.7 10.3 13.5 6.9 5.9 8.5 20.5 12.4 4.8 5.9 9.2 14.9 ANLN "ANILLIN, scra, Scraps" ENSG00000011426 "Anillin actin binding protein" Q9NQW6 7 36389821-36453791 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Actin-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 266.0" "Group enriched" "Detected in many" 5 "Early spermatids: 156.4;Oligodendrocytes: 441.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "HBF TERT88: 655.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005680, CAB033902, HPA050556, CAB062547, CAB068175" Enhanced Enhanced Nucleoplasm,Midbody Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 70: Brain - Nervous system development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm Midbody "CAB033902: AB_2058302, CAB062547: AB_2665622, CAB068175: AB_2665623, HPA005680: AB_2667388, HPA050556: AB_2681175" "unprognostic (4.23e-2)" "unprognostic (1.59e-3)" "unprognostic (1.49e-1)" "prognostic unfavorable (1.73e-4)" "unprognostic (1.67e-2)" "unprognostic (3.44e-2)" "prognostic unfavorable (5.97e-7)" "prognostic unfavorable (6.99e-5)" "unprognostic (2.69e-2)" "unprognostic (3.66e-2)" "prognostic unfavorable (2.00e-6)" "unprognostic (3.13e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (5.29e-2)" "unprognostic (1.34e-1)" "unprognostic (2.94e-2)" "unprognostic (4.04e-3)" 1.2 0.7 59.8 5.2 134.5 36.4 2.0 125.1 72.7 1.8 18.4 6.0 4.4 1.8 0.2 10.4 0.9 2.1 0.8 59.3 83.6 0.4 1.2 1.4 6.7 162.3 106.5 0.9 0.6 0.2 0.2 8.9 160.2 0.9 8.0 0.3 1.7 0.4 0.3 13.6 4.3 14.9 99.2 1.2 4.8 12.4 102.3 16.0 0.8 0.3 9.5 3.2 3.2 266.0 476.1 96.5 79.3 61.0 10.7 26.9 85.6 292.5 169.3 344.4 256.0 66.4 142.7 23.9 82.1 148.6 182.8 237.0 63.4 170.7 655.4 16.1 46.0 32.7 104.8 55.8 1.7 47.3 36.7 6.0 7.7 225.3 147.2 40.8 109.3 31.2 69.6 48.8 284.4 71.0 40.0 54.8 88.5 71.9 102.3 29.1 238.2 15.9 76.5 76.5 33.5 39.5 154.1 175.8 26.1 109.6 119.0 53.6 104.5 214.2 239.0 127.6 346.6 20.1 34.2 43.2 72.9 74.9 460.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.3 59.8 134.5 125.1 72.7 59.3 83.6 162.3 106.5 160.2 99.2 102.3 266.0 0.4 0.0 1.1 2.3 1.0 14.1 1.9 8.3 7.4 0.0 1.9 2.0 0.6 0.0 3.2 0.0 0.0 13.8 1.1 2.8 0.0 0.7 156.4 18.9 3.2 1.9 0.0 35.3 3.4 0.2 23.2 6.9 10.2 12.8 0.0 15.4 1.1 0.5 9.8 0.0 5.7 3.4 6.1 1.6 5.9 53.3 1.2 2.7 0.0 0.0 0.0 0.0 0.0 1.5 441.3 0.6 0.1 0.0 8.8 1.6 0.8 0.3 10.4 0.0 0.0 0.4 5.2 20.0 17.7 27.1 9.2 2.9 2.6 1.7 6.0 3.3 ANO1 "DOG1, FLJ10261, ORAOV2, TAOS2, TMEM16A" ENSG00000131620 "Anoctamin 1" Q5XXA6 11 70078302-70189528 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Developmental protein, Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 181.7;salivary gland: 180.5;seminal vesicle: 209.2" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 70.2;Early spermatids: 54.9;Hepatocytes: 141.3;Late spermatids: 75.1;Sertoli cells: 46.0;Smooth muscle cells: 52.5;Suprabasal keratinocytes: 46.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "A-431: 140.2;CAPAN-2: 207.9;HaCaT: 254.0;OE19: 182.2" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 6.6" "HPA032148, HPA057356" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 2: Hepatocytes - Metabolism" "Plasma membrane" Nucleoplasm "HPA032148: AB_2674180, HPA057356: AB_2732610" "unprognostic (2.73e-1)" "unprognostic (7.91e-2)" "unprognostic (3.66e-2)" "prognostic favorable (4.58e-6)" "unprognostic (1.90e-1)" "prognostic unfavorable (7.28e-5)" "unprognostic (1.16e-3)" "prognostic unfavorable (2.40e-4)" "unprognostic (2.13e-2)" "unprognostic (3.51e-1)" "prognostic unfavorable (1.70e-4)" "unprognostic (1.21e-1)" "prognostic unfavorable (4.09e-6)" "unprognostic (1.56e-1)" "unprognostic (1.06e-1)" "unprognostic (8.85e-3)" "unprognostic (1.81e-1)" 16.3 2.2 0.3 3.6 1.6 0.1 86.8 0.8 1.3 46.7 0.1 14.3 3.6 40.0 181.7 12.7 59.1 54.4 21.9 0.5 0.1 6.4 108.5 16.1 3.4 1.0 0.2 2.9 9.1 48.0 4.4 5.2 1.1 17.1 11.0 0.9 180.5 209.2 12.7 97.4 4.6 30.1 0.2 1.2 48.3 10.4 0.1 1.5 35.4 33.0 4.0 6.7 12.8 0.5 140.2 5.3 0.3 4.5 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 207.9 0.0 2.5 0.0 0.3 254.0 0.0 0.7 0.0 0.4 0.2 0.1 0.1 0.0 0.0 0.3 0.2 0.0 0.1 0.4 0.2 0.0 0.6 0.0 0.0 0.1 0.0 1.0 0.5 0.3 1.1 182.2 19.6 0.3 0.0 0.7 0.0 0.2 7.3 0.2 0.1 43.1 0.8 1.4 16.2 0.5 0.5 0.3 1.1 0.0 3.5 0.1 0.3 0.2 0.2 0.0 14.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.6 0.8 1.3 0.5 0.1 1.0 0.2 1.1 0.2 0.1 0.5 7.2 0.0 0.0 0.7 0.4 17.7 21.5 4.2 0.0 0.0 30.5 70.2 3.5 17.2 2.0 0.0 0.0 1.3 0.2 0.4 0.0 4.1 54.9 10.0 27.5 5.6 0.0 2.7 0.7 0.0 0.6 4.2 36.7 18.5 4.5 0.0 3.3 141.3 0.2 0.0 20.4 13.3 0.0 1.6 3.0 75.1 1.8 0.7 5.4 2.8 0.0 0.8 0.0 1.5 0.7 1.0 0.5 1.5 0.3 22.6 0.0 0.7 0.3 0.4 46.0 1.1 52.5 1.4 2.3 1.4 46.7 4.1 0.7 0.1 0.4 20.9 ANXA9 ANX31 ENSG00000143412 "Annexin A9" O76027 1 150982249-150995634 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cholangiocytes: 61.5;Collecting duct cells: 12.9;Ductal cells: 21.2;Hepatocytes: 17.4;Proximal tubular cells: 44.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 1.6" "Group enriched" "Detected in many" 4 "dendritic cells: 1.6;granulocytes: 1.0;monocytes: 1.2" "Cell line enhanced" "Detected in many" "CAPAN-2: 40.6;Hep G2: 42.3;MCF7: 59.2;OE19: 47.8;T-47d: 139.9" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA028404, HPA028698" Enhanced Approved "Nuclear speckles,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 6: T47d - Mammary gland" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nuclear speckles, Cytosol" "HPA028404: AB_10599190, HPA028698: AB_10600227" "unprognostic (4.06e-1)" "unprognostic (1.55e-2)" "unprognostic (3.15e-3)" "unprognostic (2.08e-3)" "unprognostic (2.93e-2)" "unprognostic (4.49e-2)" "unprognostic (1.84e-2)" "unprognostic (3.39e-2)" "unprognostic (1.08e-1)" "unprognostic (1.98e-1)" "unprognostic (2.10e-1)" "unprognostic (2.97e-1)" "prognostic favorable (8.74e-6)" "unprognostic (1.58e-2)" "unprognostic (1.11e-1)" "unprognostic (8.99e-2)" "unprognostic (1.72e-2)" 3.2 3.7 2.6 2.6 7.1 2.4 6.9 6.1 3.5 2.2 3.3 2.1 4.6 6.4 5.9 26.2 4.7 9.2 6.0 1.7 3.5 22.0 29.9 3.1 2.3 9.0 6.7 4.7 35.8 19.2 1.2 1.0 7.9 2.4 0.3 7.2 7.5 21.2 3.8 32.4 4.2 2.9 4.5 2.8 4.2 3.8 5.3 0.5 25.0 0.2 23.2 6.3 6.0 12.1 11.7 2.8 4.2 4.4 0.0 0.0 11.4 1.0 0.8 0.1 0.0 33.9 40.6 0.4 2.5 0.0 1.3 6.8 0.0 0.8 0.1 3.9 4.4 6.1 4.7 42.3 0.0 2.4 2.6 0.0 0.3 0.1 0.2 9.5 0.0 1.8 3.0 13.2 0.1 59.2 0.5 3.2 1.1 47.8 0.8 2.8 0.6 15.0 0.1 17.0 6.4 3.6 2.6 28.8 1.7 2.3 139.9 3.7 4.7 0.9 1.3 0.7 0.8 4.0 13.0 18.8 6.2 4.2 3.3 0.0 1.2 0.7 0.0 0.7 0.3 0.2 0.1 0.2 1.6 0.0 0.3 0.0 1.0 0.0 0.1 0.0 0.0 0.4 2.6 7.1 6.1 3.5 1.7 3.5 9.0 6.7 7.9 4.5 5.3 12.1 0.1 0.0 1.1 0.3 0.2 0.1 0.4 0.8 0.0 0.0 4.5 2.5 0.4 61.5 4.5 12.9 0.0 2.0 0.1 0.0 3.9 21.2 1.5 1.3 0.8 0.1 0.0 0.0 0.2 7.5 0.3 0.6 0.0 1.6 1.3 0.0 0.0 17.4 2.2 0.0 0.2 0.0 0.0 0.6 0.4 0.9 1.5 1.4 1.8 0.0 0.2 0.0 0.0 1.0 0.5 2.9 0.1 1.2 0.0 0.3 0.3 44.6 2.5 0.0 0.0 0.1 0.3 4.9 0.2 0.3 0.0 1.5 0.2 0.0 0.3 5.4 AP1M1 "AP47, CLAPM2" ENSG00000072958 "Adaptor related protein complex 1 subunit mu 1" Q9BXS5 19 16197854-16245906 "Plasma proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 92.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045256 Uncertain NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" "HPA045256: AB_10960697" "unprognostic (5.10e-2)" "unprognostic (3.71e-2)" "unprognostic (4.70e-3)" "unprognostic (2.85e-1)" "unprognostic (5.19e-2)" "unprognostic (2.05e-2)" "unprognostic (3.10e-2)" "unprognostic (3.52e-2)" "unprognostic (2.08e-1)" "unprognostic (2.15e-1)" "unprognostic (1.37e-2)" "unprognostic (1.81e-1)" "prognostic unfavorable (1.75e-4)" "unprognostic (1.02e-2)" "unprognostic (3.02e-1)" "unprognostic (2.96e-2)" "unprognostic (1.56e-1)" 49.5 47.2 30.1 30.7 31.0 58.5 37.9 22.3 36.3 32.2 22.0 37.7 32.1 38.8 9.2 29.6 29.8 21.4 39.9 33.0 31.0 39.6 81.0 31.9 36.9 26.6 30.0 31.7 18.8 20.1 24.0 27.5 33.5 25.3 12.6 17.3 21.6 24.8 44.4 30.8 31.0 35.4 23.1 37.6 27.3 60.8 25.0 37.8 23.7 29.0 28.2 38.3 29.1 25.9 63.3 70.2 69.3 65.3 82.7 80.9 39.1 69.6 74.1 99.5 103.3 83.9 48.6 49.8 78.7 76.6 64.4 35.1 54.2 56.9 111.3 85.5 122.3 80.9 63.4 114.6 67.1 91.5 96.9 83.5 42.2 89.2 59.8 65.4 95.6 69.8 40.3 98.0 109.5 75.8 131.2 55.4 56.9 22.3 162.7 87.9 56.7 67.3 54.9 45.2 44.4 99.4 56.8 34.4 64.0 36.9 41.0 73.1 83.1 111.8 45.6 151.7 134.3 104.6 141.6 54.9 125.5 112.8 88.7 89.4 142.3 243.9 104.8 180.7 105.6 99.8 103.4 111.2 121.6 92.3 115.1 147.0 101.8 133.1 235.7 131.2 161.8 174.3 30.1 31.0 22.3 36.3 33.0 31.0 26.6 30.0 33.5 23.1 25.0 25.9 17.4 41.7 31.2 12.7 30.6 4.6 7.4 13.2 11.4 35.4 11.3 10.9 17.9 14.3 15.2 12.9 20.9 32.1 30.5 8.3 15.6 21.1 32.5 10.6 27.2 22.7 19.8 21.7 11.8 18.2 40.4 28.1 8.6 14.8 27.1 19.0 21.8 41.9 42.6 42.1 11.7 7.3 6.1 36.0 13.3 92.1 23.0 30.2 10.6 5.6 34.9 18.3 38.1 4.5 12.8 31.2 5.9 19.9 24.5 6.2 25.1 23.6 13.9 40.2 0.0 26.1 22.8 61.9 23.3 12.6 7.1 17.5 32.9 17.7 9.0 4.6 AP1S2 "MRX59, MRXS5, PGS, SIGMA1B" ENSG00000182287 "Adaptor related protein complex 1 subunit sigma 2" P56377 X 15825806-15854931 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "epididymis: 663.3" "Cell type enhanced" "Detected in all" "Hofbauer cells: 259.8;Kupffer cells: 392.6;Langerhans cells: 609.2;Macrophages: 362.7;monocytes: 630.0" "Group enriched" "Detected in all" 4 "endometrial cancer: 13.1;glioma: 22.0;melanoma: 49.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 326.8;intermediate monocyte: 325.0;myeloid DC: 221.1;non-classical monocyte: 175.4;plasmacytoid DC: 82.2" "Group enriched" "Detected in all" 5 "dendritic cells: 221.1;monocytes: 326.8" "Cell line enhanced" "Detected in all" "Karpas-707: 298.0;SK-MEL-30: 442.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049894, HPA060945" Enhanced Supported "Golgi apparatus,Vesicles" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Golgi apparatus, Vesicles" "HPA049894: AB_2680939, HPA060945: AB_2684393" "prognostic favorable (9.86e-4)" "unprognostic (4.62e-2)" "unprognostic (2.11e-1)" "unprognostic (1.68e-1)" "unprognostic (2.47e-3)" "unprognostic (3.85e-1)" "unprognostic (2.03e-3)" "unprognostic (5.76e-2)" "unprognostic (1.43e-2)" "prognostic favorable (5.53e-6)" "unprognostic (1.85e-2)" "unprognostic (5.61e-2)" "unprognostic (5.08e-2)" "unprognostic (6.35e-2)" "unprognostic (3.13e-1)" "unprognostic (9.34e-2)" "unprognostic (6.47e-2)" 28.3 21.4 24.6 36.7 28.4 38.3 15.0 32.0 36.9 31.6 27.3 42.1 11.9 52.2 663.3 21.4 13.5 20.1 74.8 25.1 48.0 13.1 15.9 25.8 33.2 42.7 35.8 8.8 7.8 16.7 19.4 42.0 47.0 11.6 22.0 43.7 9.5 30.5 70.1 14.0 20.1 76.3 34.4 43.0 19.5 23.4 29.6 28.7 12.5 93.7 28.8 26.1 12.7 33.8 12.0 14.2 130.1 78.4 29.5 19.1 5.0 47.1 22.7 31.1 41.1 9.6 11.1 22.6 183.0 72.6 50.4 16.1 31.7 10.8 57.0 30.1 64.9 15.3 16.7 14.7 24.2 63.1 16.9 12.2 11.2 36.0 33.1 50.4 78.1 19.1 14.3 298.0 72.4 8.7 12.9 39.5 171.0 6.4 42.5 29.5 116.7 50.6 37.4 2.5 14.8 69.2 18.4 4.8 442.2 84.1 52.7 69.2 43.9 67.8 21.2 92.5 41.9 25.5 58.7 37.3 33.6 28.0 159.7 50.9 326.8 34.6 21.1 325.0 24.8 30.8 25.5 20.6 221.1 28.0 18.5 18.1 52.8 27.9 175.4 82.2 38.1 228.0 24.6 28.4 32.0 36.9 25.1 48.0 42.7 35.8 47.0 34.4 29.6 33.8 130.8 3.2 13.1 37.2 77.0 55.2 12.7 9.1 8.6 34.7 12.0 11.4 195.6 12.8 3.2 9.2 12.5 5.3 114.2 9.2 33.2 13.7 5.1 50.4 32.6 166.3 26.9 32.6 15.1 6.4 18.9 38.0 7.7 78.0 78.6 15.6 147.4 8.6 259.8 11.8 73.2 8.4 12.2 392.6 609.2 17.5 17.4 362.7 149.4 31.9 630.0 21.1 62.8 19.1 85.0 10.3 14.0 7.2 26.0 19.0 6.5 9.0 1.6 39.3 39.5 26.7 39.1 55.7 28.8 10.6 51.6 5.6 58.3 4.0 8.5 6.7 AP2B1 "ADTB2, CLAPB1" ENSG00000006125 "Adaptor related protein complex 2 subunit beta 1" P63010 17 35578046-35726413 "Cancer-related genes, Predicted intracellular proteins, Transporters" "Endocytosis, Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 503.9;Late spermatids: 739.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017631, HPA056733, HPA067983" Approved Supported Vesicles NA NA 380000 "Cluster 2: Granulocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "CAB017631: AB_2058201, HPA056733: AB_2683219, HPA067983: AB_2732777" "unprognostic (1.49e-2)" "unprognostic (4.04e-3)" "unprognostic (2.15e-3)" "unprognostic (1.48e-1)" "unprognostic (1.16e-1)" "unprognostic (3.01e-2)" "unprognostic (1.51e-3)" "unprognostic (2.64e-2)" "unprognostic (1.06e-1)" "unprognostic (4.73e-2)" "unprognostic (2.58e-2)" "unprognostic (2.50e-1)" "prognostic favorable (2.62e-4)" "unprognostic (1.70e-1)" "unprognostic (1.10e-1)" "unprognostic (3.25e-2)" "unprognostic (1.57e-2)" 46.4 42.4 77.0 38.2 87.8 49.2 58.3 69.9 88.7 54.1 76.6 67.6 33.5 41.7 70.7 25.1 46.7 42.3 67.6 92.1 83.5 69.0 35.0 53.4 38.6 69.8 78.6 57.2 33.2 126.4 55.0 66.8 76.8 40.9 84.0 76.1 41.9 50.1 57.5 29.9 38.8 56.0 80.3 42.0 48.4 93.5 78.7 59.7 65.1 61.0 45.5 46.8 34.4 95.0 188.8 233.9 113.7 132.0 184.4 202.8 51.6 94.3 138.9 131.0 141.1 129.0 154.6 90.5 81.1 175.3 168.8 173.2 162.5 264.8 190.8 108.6 147.0 117.7 161.8 71.0 104.7 119.3 80.8 128.9 104.3 134.5 209.3 151.2 211.4 111.8 190.6 126.9 206.9 36.9 113.7 58.7 94.2 98.9 164.5 94.3 165.1 64.7 166.2 108.3 94.4 114.1 114.5 39.6 126.9 273.3 161.5 78.5 211.5 99.3 93.4 109.8 142.1 53.0 106.1 84.7 124.1 86.9 112.5 19.6 11.8 16.7 16.0 15.3 16.9 12.1 13.9 14.3 10.7 11.9 6.3 8.0 13.3 9.6 16.8 10.7 20.5 11.0 77.0 87.8 69.9 88.7 92.1 83.5 69.8 78.6 76.8 80.3 78.7 95.0 76.5 16.0 17.0 49.3 45.9 31.1 26.3 57.4 70.6 67.6 88.9 50.9 62.5 68.6 37.4 112.2 56.3 29.7 70.7 97.4 117.4 105.0 503.9 74.5 83.7 56.8 71.3 214.7 105.5 120.2 42.8 47.1 36.2 85.4 41.2 46.5 79.9 64.5 44.1 69.0 109.8 79.4 28.5 54.3 25.9 739.2 58.7 37.2 16.0 60.0 47.3 52.6 74.2 81.4 89.0 177.9 46.6 68.4 32.1 37.4 39.4 102.5 30.4 40.9 59.2 25.3 37.6 258.8 60.0 19.6 14.6 32.8 49.2 37.3 89.8 29.1 AP5S1 "C20orf29, FLJ11168" ENSG00000125843 "Adaptor related protein complex 5 subunit sigma 1" Q9NUS5 20 3820524-3828838 "Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034200, HPA043533, HPA048244" Uncertain Approved Nucleoplasm,Cytosol No No "Cluster 39: Non-specific - mRNA processing" "Cluster 39: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Cytosol" "CAB034200: AB_1564201, HPA043533: AB_2732507, HPA048244: AB_2680328" "unprognostic (1.07e-2)" "unprognostic (1.43e-1)" "unprognostic (8.52e-2)" "unprognostic (2.74e-2)" "unprognostic (1.34e-1)" "unprognostic (2.05e-2)" "unprognostic (5.49e-2)" "unprognostic (7.76e-2)" "unprognostic (1.33e-1)" "unprognostic (8.91e-2)" "unprognostic (5.15e-3)" "unprognostic (8.17e-2)" "prognostic favorable (5.53e-5)" "unprognostic (2.92e-1)" "unprognostic (1.62e-1)" "unprognostic (6.09e-3)" "unprognostic (5.08e-2)" 6.0 11.5 7.1 5.5 7.7 7.4 5.8 6.4 8.2 4.8 8.1 6.2 6.3 5.7 3.0 7.4 4.7 4.6 11.3 7.3 6.7 9.4 14.6 5.4 5.5 6.8 6.5 5.8 7.5 7.8 7.5 5.4 6.5 6.9 4.4 3.4 8.7 3.6 19.2 5.3 6.4 3.9 6.3 8.2 6.4 11.2 6.6 4.3 9.4 10.0 3.8 5.4 5.1 6.5 18.1 33.8 4.6 3.1 6.2 8.0 5.7 10.8 8.6 10.4 8.3 28.5 18.9 10.4 11.3 11.4 19.7 15.9 3.9 17.4 3.6 5.7 10.9 17.3 10.1 25.3 10.7 12.0 10.0 13.7 9.7 13.0 10.3 7.0 12.4 12.4 12.4 19.8 14.0 29.4 28.0 10.5 4.2 13.0 27.3 11.7 7.8 10.8 11.8 14.4 14.2 5.7 10.6 32.4 18.2 3.1 15.9 5.9 16.9 21.7 10.3 11.3 20.6 10.6 12.6 5.7 7.5 10.6 19.0 2.2 7.5 4.6 10.2 11.9 7.8 5.4 8.5 8.4 9.9 7.0 7.8 7.3 1.7 6.2 6.7 7.7 9.9 6.5 7.1 7.7 6.4 8.2 7.3 6.7 6.8 6.5 6.5 6.3 6.6 6.5 4.0 0.0 10.6 2.3 5.9 1.7 4.4 8.0 7.4 15.3 4.9 4.3 11.2 11.5 5.9 3.7 10.4 19.4 3.8 8.4 11.7 11.1 3.7 5.1 6.2 8.6 12.6 9.9 1.9 12.7 13.3 6.8 14.8 5.2 14.0 6.6 6.1 9.4 15.5 25.2 2.1 7.3 8.2 6.9 2.0 3.6 5.9 7.3 5.4 4.7 11.0 12.8 8.2 2.5 1.7 10.2 8.8 4.1 8.6 3.6 11.2 8.5 4.5 20.8 13.1 5.8 4.5 19.4 10.9 6.8 1.0 18.5 6.2 10.9 7.4 3.0 APBB1IP "INAG1, RIAM" ENSG00000077420 "Amyloid beta precursor protein binding family B member 1 interacting protein" Q7Z5R6 10 26438341-26567803 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 145.4" "Cell type enhanced" "Detected in many" "B-cells: 88.2;dendritic cells: 149.1;Kupffer cells: 117.7;Macrophages: 93.4;Microglial cells: 381.3;NK-cells: 134.9;T-cells: 125.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 182.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 101.0;MOLT-4: 87.7;REH: 195.4;U-698: 204.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA017009, HPA063903" Enhanced Enhanced "Plasma membrane,Cytosol" No NA "Cluster 1: Neutrophils - Mixed function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Cytosol" "HPA017009: AB_2669505, HPA063903: AB_2685147" "unprognostic (1.31e-2)" "unprognostic (3.26e-2)" "unprognostic (2.79e-3)" "prognostic favorable (7.48e-4)" "unprognostic (3.06e-1)" "unprognostic (1.07e-2)" "unprognostic (3.83e-2)" "unprognostic (3.05e-1)" "unprognostic (1.62e-2)" "unprognostic (3.74e-1)" "unprognostic (5.72e-2)" "unprognostic (9.75e-2)" "unprognostic (1.71e-1)" "unprognostic (7.77e-3)" "unprognostic (2.68e-2)" "unprognostic (6.00e-2)" "unprognostic (2.38e-2)" 30.7 4.7 7.0 47.8 8.0 45.5 14.5 10.4 7.6 3.5 5.7 6.1 7.1 2.2 1.6 3.4 5.9 11.6 5.7 7.6 10.4 5.0 38.3 15.5 50.0 16.4 12.5 1.5 4.3 1.6 2.8 8.8 18.0 2.6 6.7 0.6 5.1 2.1 1.4 3.4 17.8 7.5 16.0 56.6 9.2 0.8 15.5 145.4 3.5 2.7 44.3 10.5 3.6 27.3 0.1 1.8 0.0 0.0 12.8 21.2 11.3 37.0 7.2 20.8 19.8 0.0 0.0 101.0 0.5 24.9 22.2 0.1 0.0 0.0 28.6 0.0 0.0 73.3 0.2 0.0 0.0 13.9 0.1 30.3 0.0 0.7 0.0 2.6 0.0 40.5 0.1 62.0 0.0 0.0 87.7 19.5 0.1 7.9 0.0 195.4 0.1 72.4 5.8 0.0 0.1 0.0 3.4 0.3 0.1 0.3 0.1 47.6 0.1 0.0 0.5 6.8 0.1 16.8 0.0 204.7 16.9 71.0 0.0 81.5 23.8 58.5 30.2 23.6 24.9 32.6 25.8 25.9 15.4 39.5 29.3 28.8 182.9 19.1 38.9 50.3 27.2 13.4 7.0 8.0 10.4 7.6 7.6 10.4 16.4 12.5 18.0 16.0 15.5 27.3 3.2 0.0 25.3 1.6 88.2 1.1 0.1 0.1 0.6 0.1 1.6 3.2 1.0 8.6 2.6 3.7 0.0 2.2 149.1 0.1 0.0 3.9 0.4 0.7 12.8 4.7 0.0 28.2 1.1 0.0 20.7 15.0 3.6 0.4 23.4 0.1 6.8 28.9 59.9 0.0 2.9 0.2 0.0 117.7 18.4 0.3 0.0 93.4 3.6 381.3 65.2 0.0 134.9 4.0 1.5 0.1 0.1 0.0 41.7 0.1 0.0 5.1 3.7 0.2 0.0 0.9 11.3 0.1 1.1 0.4 0.1 1.4 125.9 0.4 0.1 0.1 APOBEC3C "APOBEC1L, ARDC2, ARDC4, ARP5, bK150C2.3, PBI" ENSG00000244509 "Apolipoprotein B mRNA editing enzyme catalytic subunit 3C" Q9NRW3 22 39014257-39020352 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cells: 117.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "CAB033048, HPA071523" Approved Approved "Intermediate filaments" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 34: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Intermediate filaments" "CAB033048: AB_2057401, HPA071523: AB_2686409" "unprognostic (1.79e-3)" "prognostic favorable (1.08e-5)" "unprognostic (4.32e-3)" "unprognostic (3.20e-3)" "unprognostic (4.68e-2)" "unprognostic (2.13e-1)" "unprognostic (5.18e-2)" "unprognostic (2.55e-1)" "unprognostic (1.10e-1)" "unprognostic (1.08e-3)" "unprognostic (7.40e-2)" "unprognostic (4.10e-2)" "prognostic unfavorable (8.91e-10)" "unprognostic (5.92e-2)" "unprognostic (1.11e-1)" "unprognostic (4.10e-1)" "unprognostic (3.52e-3)" 12.3 36.2 3.1 31.1 3.2 31.4 12.3 3.1 4.0 23.1 3.5 20.2 14.0 22.6 51.7 22.7 56.0 18.4 24.0 3.0 3.5 6.0 7.0 20.6 57.8 5.0 3.6 38.2 5.1 10.5 3.8 11.6 5.1 25.9 33.1 3.4 22.1 36.1 2.7 19.8 17.4 30.8 4.5 36.5 18.1 29.4 3.9 25.2 15.2 11.3 67.8 27.6 17.3 6.5 39.4 38.1 6.3 73.9 40.2 82.6 32.4 28.3 54.9 41.0 54.5 36.8 43.7 115.5 18.6 56.1 26.2 39.4 6.5 120.2 39.5 44.3 32.0 111.8 1.6 30.6 43.5 73.4 107.1 90.5 68.1 54.0 13.3 20.4 23.0 0.9 69.9 142.3 83.0 0.4 29.6 39.8 9.8 0.5 82.8 51.1 16.9 96.6 27.2 51.4 1.9 4.9 40.9 0.2 21.7 15.9 0.2 26.8 11.9 21.8 37.1 11.9 12.4 38.6 42.7 9.5 66.9 47.1 58.8 86.6 104.4 277.0 309.1 220.6 212.6 241.6 164.7 276.9 106.9 249.1 54.0 196.9 14.1 196.9 247.8 86.9 168.9 173.6 3.1 3.2 3.1 4.0 3.0 3.5 5.0 3.6 5.1 4.5 3.9 6.5 3.3 3.2 16.2 0.0 68.8 25.2 45.4 44.1 24.5 0.2 16.4 8.9 23.0 28.6 18.4 7.3 0.0 4.3 60.2 56.6 0.0 31.6 3.2 11.0 16.4 9.6 26.4 57.2 0.0 1.3 1.4 26.5 5.6 15.6 57.0 78.6 30.0 1.2 61.9 0.0 0.0 17.8 28.5 49.0 37.3 9.3 57.8 34.2 44.4 0.0 65.1 24.4 117.4 0.5 0.0 11.5 16.6 38.0 55.4 18.9 3.2 1.3 13.6 0.8 26.3 11.9 20.1 1.5 1.5 9.7 16.3 1.9 67.7 53.5 18.8 41.9 APOBEC3G "bK150C2.7, CEM15, dJ494G10.1, FLJ12740, MDS019" ENSG00000239713 "Apolipoprotein B mRNA editing enzyme catalytic subunit 3G" Q9HC16 22 39077067-39087743 "Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 45.9" "Cell type enhanced" "Detected in many" "dendritic cells: 145.4;monocytes: 69.1;NK-cells: 251.3;Plasma cells: 69.5;T-cells: 120.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+ RasG12V: 30.0;Daudi: 38.3;HDLM-2: 31.8;Karpas-707: 44.2" "HPA001812, HPA073637" Enhanced Uncertain Nucleoplasm,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Cytosol" "HPA001812: AB_1078175, HPA073637: " "prognostic favorable (4.78e-4)" "prognostic favorable (4.70e-4)" "unprognostic (8.18e-3)" "prognostic favorable (6.03e-5)" "unprognostic (2.37e-1)" "unprognostic (3.43e-1)" "unprognostic (7.77e-2)" "unprognostic (2.33e-1)" "unprognostic (4.23e-1)" "unprognostic (4.13e-3)" "unprognostic (9.13e-3)" "unprognostic (1.81e-1)" "prognostic unfavorable (8.66e-13)" "unprognostic (3.41e-2)" "unprognostic (5.83e-2)" "unprognostic (2.91e-2)" "prognostic favorable (6.30e-4)" 5.5 8.1 3.3 21.7 3.2 15.9 8.6 3.4 4.6 7.7 2.9 7.6 5.5 10.3 10.4 6.1 21.1 11.1 4.3 3.0 4.0 4.1 5.7 14.5 45.9 3.9 3.7 22.7 1.7 4.8 3.5 5.0 3.9 7.8 9.4 1.4 8.5 22.4 1.2 1.6 9.6 9.6 4.0 28.2 10.0 20.1 3.4 25.9 5.8 2.7 35.1 15.7 6.4 4.5 4.5 0.1 0.0 0.0 5.0 9.7 0.3 1.0 16.8 19.9 30.0 1.6 22.6 38.3 0.5 7.3 11.6 0.1 0.2 1.3 6.0 31.8 0.1 23.1 0.0 0.2 21.8 7.1 10.1 14.3 0.5 10.9 2.4 0.0 2.4 1.2 1.9 44.2 3.1 0.0 7.6 7.7 0.6 0.0 1.7 15.3 0.0 25.8 0.0 19.6 0.0 0.0 0.5 0.0 2.0 1.7 0.0 13.2 0.0 2.8 0.2 0.0 0.0 0.0 3.5 0.5 3.2 6.9 5.0 30.7 42.3 28.7 363.8 98.1 207.6 84.9 108.8 281.7 52.4 66.1 34.3 160.2 34.8 232.2 123.0 28.1 92.3 297.8 3.3 3.2 3.4 4.6 3.0 4.0 3.9 3.7 3.9 4.0 3.4 4.5 8.4 3.2 8.9 1.0 55.7 1.8 15.5 27.0 4.6 0.4 3.0 6.6 3.7 7.2 14.4 0.0 2.1 3.9 145.4 0.6 5.9 11.7 47.2 5.7 6.4 8.9 6.0 8.6 0.1 2.3 1.1 10.0 2.0 3.9 12.6 62.5 11.4 0.9 30.6 0.0 0.1 1.9 10.2 20.4 9.8 13.7 19.0 21.3 7.2 3.7 69.1 8.1 251.3 0.5 0.0 2.2 1.8 9.1 69.5 16.0 0.1 2.1 12.1 1.2 19.7 4.7 10.1 1.3 1.6 2.0 1.3 1.0 120.5 20.3 1.5 18.0 APOL3 "APOLIII, CG12-1" ENSG00000128284 "Apolipoprotein L3" O95236 22 36140330-36166177 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 59.1;Endothelial cells: 69.8;Hepatic stellate cells: 69.7;Kupffer cells: 38.7;NK-cells: 46.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 34.1;ASC TERT1: 54.1;HDLM-2: 25.6;Karpas-707: 59.0" "Intracellular and membrane" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 64: Macrophages - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "prognostic favorable (6.82e-4)" "unprognostic (5.93e-3)" "unprognostic (6.79e-2)" "unprognostic (2.70e-2)" "unprognostic (2.22e-1)" "unprognostic (7.05e-2)" "unprognostic (6.30e-2)" "unprognostic (2.67e-1)" "unprognostic (8.94e-2)" "unprognostic (1.09e-1)" "unprognostic (2.95e-3)" "unprognostic (2.46e-1)" "prognostic unfavorable (1.23e-5)" "unprognostic (7.87e-2)" "unprognostic (4.69e-2)" "unprognostic (1.07e-1)" "unprognostic (1.07e-2)" 58.2 12.3 10.1 25.4 10.0 10.1 43.7 8.7 12.2 17.2 7.6 16.3 15.0 18.8 12.3 12.0 24.4 14.3 33.7 8.8 9.1 19.0 39.9 42.0 43.4 11.4 10.1 9.6 6.3 3.4 8.5 16.3 10.0 18.4 11.4 0.6 15.7 14.9 16.6 19.6 21.7 16.0 8.8 47.6 12.3 2.9 10.8 18.1 25.2 19.6 20.8 17.6 19.5 8.7 4.3 0.0 0.0 0.1 34.1 54.1 1.8 1.8 10.2 3.1 7.0 0.0 9.5 2.1 0.4 5.0 4.6 0.7 0.0 1.3 1.9 25.6 0.0 9.2 1.3 2.1 18.3 0.1 2.6 11.4 0.0 9.0 0.4 2.1 22.1 2.0 0.2 59.0 1.1 0.1 11.7 0.3 0.1 0.0 0.5 16.9 0.0 1.3 0.3 3.0 0.2 0.1 6.0 4.2 0.1 0.0 0.0 1.2 16.2 1.5 0.6 1.7 0.5 15.6 10.8 0.1 3.7 3.5 1.5 8.3 19.1 0.8 16.9 23.4 27.3 9.7 14.4 17.5 15.4 8.0 13.4 14.3 2.3 18.5 24.6 0.5 14.7 17.2 10.1 10.0 8.7 12.2 8.8 9.1 11.4 10.1 10.0 8.8 10.8 8.7 59.1 3.2 8.6 1.6 21.1 5.0 4.3 3.9 2.2 0.0 5.8 4.2 7.9 8.6 4.3 3.7 0.0 1.9 16.0 0.3 0.0 2.5 0.9 1.8 4.7 69.8 0.0 20.6 0.0 1.6 1.2 18.8 7.1 1.3 9.5 2.0 69.7 20.6 6.9 0.0 0.0 7.5 2.0 38.7 10.6 1.4 24.2 19.6 3.6 9.4 29.2 0.7 46.4 0.0 0.0 3.0 0.1 9.8 15.3 10.4 5.3 2.8 4.2 0.3 13.1 3.2 10.1 0.2 0.3 4.1 4.1 0.8 31.5 4.3 2.3 4.7 AQP1 "CHIP28, CO" ENSG00000240583 "Aquaporin 1 (Colton blood group)" P29972 7 30911853-30925517 "Blood group antigen proteins, Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Blood group antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 727.9;Alveolar cells type 2: 231.8;Cholangiocytes: 358.9;Endothelial cells: 606.7;Hepatic stellate cells: 325.6;Proximal tubular cells: 319.7" "Cancer enhanced" "Detected in all" "glioma: 336.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 34.7;HeLa: 12.5;SH-SY5Y: 14.7;U-2 OS: 14.9;WM-115: 76.4" "Group enriched" "Detected in some" 6 "medulla oblongata: 5.5;spinal cord: 22.0" "CAB001707, HPA019206" Enhanced Supported "Plasma membrane" NA NA 49000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "CAB001707: , HPA019206: AB_1844965" "unprognostic (4.18e-2)" "unprognostic (7.82e-3)" "unprognostic (1.10e-2)" "unprognostic (1.08e-1)" "unprognostic (1.02e-1)" "prognostic favorable (6.52e-4)" "unprognostic (1.95e-3)" "unprognostic (1.66e-1)" "unprognostic (3.00e-2)" "unprognostic (3.80e-2)" "unprognostic (4.16e-1)" "unprognostic (2.05e-2)" "prognostic favorable (1.32e-8)" "unprognostic (3.43e-2)" "unprognostic (1.61e-1)" "unprognostic (2.09e-1)" "unprognostic (7.21e-2)" 385.9 30.5 86.5 29.3 149.4 50.7 250.3 106.2 79.1 148.9 277.7 97.7 51.0 160.8 41.7 143.5 165.8 162.3 206.8 141.0 124.4 522.9 12.9 413.9 45.5 512.3 181.1 28.1 257.6 48.2 15.2 36.9 199.5 83.8 32.6 0.7 114.0 84.4 199.0 112.6 90.8 142.4 357.3 12.6 80.4 7.8 138.8 39.0 113.2 388.6 34.2 138.5 143.2 432.4 0.1 0.5 0.3 0.6 0.3 1.3 0.7 2.4 0.5 0.0 0.0 0.2 0.8 0.1 34.7 1.9 0.1 0.4 0.0 0.0 0.0 0.3 0.3 0.5 12.5 0.0 0.3 0.3 0.1 4.9 0.1 0.3 0.0 0.1 5.1 0.1 2.3 0.1 0.0 0.0 0.0 0.9 0.7 1.0 0.0 0.0 8.9 0.3 0.9 0.0 0.3 14.7 1.9 1.2 0.0 4.6 0.3 0.1 0.0 0.0 14.9 1.1 0.5 0.8 0.6 0.6 0.0 0.1 76.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 86.5 149.4 106.2 79.1 141.0 124.4 512.3 181.1 199.5 357.3 138.8 432.4 727.9 179.5 231.8 75.7 3.6 91.5 1.2 0.3 5.2 0.7 11.5 29.0 78.0 358.9 3.9 31.3 8.4 3.4 3.7 3.7 29.4 53.3 2.3 2.5 1.2 606.7 7.3 86.9 3.5 2.5 4.8 67.6 0.0 0.9 1.3 0.5 325.6 2.0 3.7 0.0 1.0 28.6 0.0 5.1 107.7 2.1 1.2 6.0 88.9 0.0 1.6 0.4 0.0 0.5 0.2 2.4 14.5 3.4 3.7 1.2 90.6 319.7 6.2 0.4 13.1 23.1 42.3 0.3 1.5 2.6 78.7 7.3 8.1 4.7 67.8 1.0 AQP11 ENSG00000178301 "Aquaporin 11" Q8NBQ7 11 77589391-77610356 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 28.6;liver: 16.1" "Cell type enhanced" "Detected in many" "Early spermatids: 42.0;Hepatocytes: 35.9;Late spermatids: 65.0;Muller glia cells: 30.7;Proximal enterocytes: 33.2;Spermatocytes: 56.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 8.2;GAMG: 12.3;Hep G2: 13.6;OE19: 7.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042879 Approved Nucleoplasm,Vesicles NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm Vesicles "HPA042879: AB_10794919" "unprognostic (4.95e-2)" "unprognostic (7.61e-2)" "unprognostic (2.15e-2)" "unprognostic (9.62e-5)" "unprognostic (2.42e-1)" "unprognostic (2.79e-1)" "unprognostic (1.42e-1)" "unprognostic (3.48e-2)" "unprognostic (2.65e-1)" "prognostic favorable (9.89e-4)" "unprognostic (1.16e-1)" "unprognostic (1.00e-1)" "unprognostic (1.73e-1)" "unprognostic (1.73e-2)" "unprognostic (2.44e-1)" "unprognostic (6.46e-2)" "unprognostic (1.66e-3)" 1.0 13.2 3.4 0.7 3.0 0.6 1.2 4.6 3.3 0.8 1.0 2.3 28.6 0.8 1.0 0.4 0.8 1.2 0.8 2.6 3.4 6.0 16.1 0.5 0.8 3.3 3.1 6.0 4.0 0.5 1.5 0.8 3.5 4.0 2.1 5.6 0.7 0.4 0.9 0.9 25.3 0.4 2.7 0.9 2.4 8.1 3.0 0.1 1.5 0.2 0.1 0.8 0.6 3.0 1.0 3.4 1.4 2.2 3.1 0.8 1.3 1.6 0.8 1.6 0.7 8.2 1.6 1.6 0.7 0.8 12.3 0.9 0.6 0.1 0.8 4.7 1.2 1.3 1.3 13.6 1.0 2.8 1.4 0.8 0.3 0.9 0.2 1.9 0.3 0.4 0.9 1.0 1.9 1.7 0.9 2.0 1.4 7.8 3.1 1.3 3.3 0.6 0.9 1.2 1.3 0.9 2.1 0.5 0.8 1.1 1.5 0.3 0.9 1.2 3.7 2.4 1.0 1.0 0.8 1.3 0.4 0.2 1.8 0.0 0.0 0.1 0.5 0.0 0.3 0.0 0.2 0.4 0.0 0.5 0.6 0.2 0.0 0.7 0.0 0.0 0.0 0.2 3.4 3.0 4.6 3.3 2.6 3.4 3.3 3.1 3.5 2.7 3.0 3.0 0.6 0.0 0.0 3.9 0.8 0.1 0.9 0.4 1.8 7.5 2.1 1.3 0.7 7.2 0.2 1.8 0.0 7.5 0.6 10.8 0.0 1.1 42.0 1.2 0.8 0.5 4.2 0.0 13.5 4.0 11.4 1.5 3.6 0.8 4.5 17.1 0.4 35.9 1.2 0.0 14.6 2.9 0.0 0.6 0.4 65.0 15.5 0.5 1.8 1.0 0.0 30.7 0.0 9.0 9.9 2.5 5.5 11.3 0.3 1.4 33.2 19.9 0.2 5.0 0.0 0.5 1.2 56.0 6.4 0.4 0.1 15.9 0.7 21.4 6.4 0.4 AR "AIS, DHTR, HUMARA, NR3C4, SBMA, SMAX1" ENSG00000169083 "Androgen receptor" P10275 X 67544021-67730619 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "Cancer-related genes, Disease variant, FDA approved drug targets, Neurodegeneration, Pseudohermaphroditism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 38.2" "Cell type enhanced" "Detected in many" "Breast glandular cells: 93.7;Granulosa cells: 104.8;Hepatocytes: 269.2;Leydig cells: 77.9;Peritubular cells: 86.5;Skeletal myocytes: 75.0" "Cancer enhanced" "Detected in many" "breast cancer: 15.6;prostate cancer: 16.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 13.3;BJ hTERT+: 10.3;HAP1: 14.9;LHCN-M2: 16.1;RH-30: 23.6;T-47d: 10.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB000001, HPA004733, CAB065764" Enhanced Supported Cytosol NA NA "Cluster 85: Liver - Metabolism" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 35: Glandular cells - Unknown function" Cytosol "CAB000001: AB_2060174, CAB065764: AB_10620739, HPA004733: " "unprognostic (1.34e-1)" "unprognostic (8.10e-3)" "unprognostic (2.49e-2)" "unprognostic (5.95e-2)" "unprognostic (1.04e-2)" "unprognostic (3.35e-2)" "prognostic favorable (8.77e-4)" "unprognostic (4.99e-2)" "unprognostic (1.72e-1)" "unprognostic (7.79e-2)" "unprognostic (2.30e-1)" "unprognostic (2.29e-1)" "prognostic favorable (1.03e-8)" "unprognostic (8.23e-3)" "unprognostic (8.90e-2)" "unprognostic (4.23e-2)" "unprognostic (7.97e-2)" 6.7 1.0 1.1 0.5 1.3 0.0 8.7 1.7 1.1 23.6 0.2 2.0 0.2 18.6 16.1 1.2 20.7 2.0 5.8 1.0 3.5 3.6 38.2 1.5 0.3 3.5 2.6 14.6 0.8 0.1 1.9 0.1 2.7 16.5 0.6 0.2 1.4 18.2 13.9 5.2 0.9 9.5 2.1 1.3 1.5 3.9 4.8 2.7 2.1 6.1 0.5 3.5 12.9 2.0 0.0 4.8 13.3 0.0 0.0 0.0 0.0 7.3 10.3 0.3 0.1 0.1 0.0 0.0 0.0 1.0 0.0 0.0 14.9 0.0 0.0 0.0 2.4 0.0 1.5 0.0 0.8 0.0 0.0 5.5 0.0 1.8 0.0 0.0 3.9 0.1 4.6 2.2 16.1 1.5 0.0 0.0 5.4 0.0 0.0 0.0 23.6 0.1 0.4 0.0 0.0 0.0 0.0 0.3 0.0 3.6 10.9 7.6 0.3 0.3 2.2 0.0 3.5 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.3 1.7 1.1 1.0 3.5 3.5 2.6 2.7 2.1 4.8 2.0 3.1 0.0 5.0 28.4 0.4 9.7 17.8 0.2 15.9 0.7 93.7 33.7 37.4 14.3 10.7 3.7 0.0 3.5 14.0 0.0 1.9 11.3 1.1 2.9 49.1 10.5 0.0 5.3 7.7 0.0 0.2 39.4 0.0 5.8 1.3 104.8 36.0 269.2 0.8 0.0 17.8 0.3 0.0 2.2 4.2 4.4 77.9 3.3 10.6 1.0 1.7 0.2 0.0 26.7 0.2 0.6 0.0 86.5 0.0 36.5 0.6 27.7 3.6 0.3 65.7 75.0 20.8 0.8 3.3 12.7 16.1 1.0 1.7 37.8 0.2 22.0 ARAP1 CENTD2 ENSG00000186635 "ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1" Q96P48 11 72685069-72793599 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020703, HPA070383" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA 36000 "Cluster 51: Monocytes - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Plasma membrane" "Vesicles, Cytosol" "CAB020703: , HPA070383: AB_2686262" "unprognostic (3.60e-2)" "unprognostic (7.68e-2)" "unprognostic (6.19e-2)" "unprognostic (5.98e-2)" "unprognostic (5.76e-2)" "unprognostic (1.64e-2)" "prognostic unfavorable (6.45e-4)" "unprognostic (4.01e-2)" "unprognostic (4.07e-1)" "unprognostic (5.95e-2)" "prognostic favorable (2.04e-5)" "unprognostic (1.84e-1)" "unprognostic (1.05e-3)" "unprognostic (6.93e-2)" "unprognostic (2.57e-2)" "prognostic favorable (6.41e-4)" "unprognostic (7.56e-3)" 41.5 63.5 40.0 58.6 48.6 97.5 33.4 37.9 50.4 44.1 62.9 35.5 29.6 38.9 14.0 37.7 48.3 44.2 42.9 42.2 38.5 47.8 40.2 71.8 53.4 50.6 42.3 49.4 37.1 20.4 48.9 35.5 45.9 44.9 18.2 8.6 33.3 25.7 20.1 47.1 43.3 28.7 40.1 117.5 31.3 16.4 50.8 32.2 46.6 20.1 25.2 39.7 37.5 56.8 19.7 41.9 15.2 18.5 63.4 42.9 23.1 26.2 46.5 29.8 29.3 56.0 50.8 42.9 51.3 44.4 40.7 64.5 23.2 64.4 12.5 50.9 28.4 36.6 40.3 81.9 43.7 25.1 98.7 47.5 65.4 48.7 23.4 36.2 33.2 31.3 31.5 17.4 13.9 40.3 38.9 89.3 9.5 35.1 25.9 36.8 23.2 21.3 27.5 61.1 15.7 32.0 19.1 27.9 84.8 19.5 25.1 56.8 37.5 41.0 28.5 42.8 16.4 27.4 14.3 23.0 21.8 37.4 22.3 19.3 24.8 30.7 8.9 39.4 5.2 6.6 5.9 6.8 15.9 4.7 4.5 5.4 50.8 13.4 51.3 5.3 6.7 17.6 40.0 48.6 37.9 50.4 42.2 38.5 50.6 42.3 45.9 40.1 50.8 56.8 8.9 28.9 32.3 33.6 16.1 7.4 7.5 14.3 15.4 4.3 8.7 7.9 2.6 7.2 9.0 16.5 33.3 9.2 18.3 16.5 9.8 13.5 50.1 14.1 11.7 7.8 23.3 9.9 7.7 7.5 8.9 22.4 16.3 9.1 10.8 36.9 9.7 10.8 43.0 0.0 7.0 12.8 12.2 45.6 25.1 6.4 20.8 57.3 8.8 30.0 29.0 7.4 21.6 17.6 31.5 12.1 10.9 15.1 12.3 4.8 20.9 5.3 20.2 2.8 0.0 8.6 8.8 0.4 2.8 10.8 5.4 4.9 12.4 10.5 15.1 7.4 ARFGAP3 ARFGAP1 ENSG00000242247 "ADP ribosylation factor GTPase activating protein 3" Q9NP61 22 42796502-42858106 "Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000638 Approved Supported "Golgi apparatus,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "Golgi apparatus" "HPA000638: AB_1078188" "unprognostic (3.29e-2)" "unprognostic (6.08e-2)" "unprognostic (3.22e-1)" "prognostic favorable (8.97e-6)" "unprognostic (5.83e-2)" "unprognostic (8.85e-3)" "unprognostic (5.00e-3)" "unprognostic (1.00e-1)" "unprognostic (2.05e-1)" "unprognostic (1.31e-1)" "unprognostic (9.06e-3)" "unprognostic (1.67e-1)" "unprognostic (1.87e-1)" "unprognostic (2.52e-2)" "unprognostic (2.08e-1)" "prognostic unfavorable (2.65e-4)" "unprognostic (1.73e-1)" 30.1 88.9 16.5 34.1 17.4 47.8 30.9 19.5 20.4 56.1 23.2 26.9 36.5 32.2 53.3 22.1 22.9 36.6 23.6 17.9 20.6 53.2 49.2 32.3 28.1 20.5 18.7 20.7 85.8 38.0 38.1 34.8 20.3 64.7 30.6 35.5 68.5 40.2 31.3 20.7 51.1 30.8 19.0 26.0 43.2 49.5 19.6 25.9 61.3 21.8 32.6 45.2 23.4 21.0 59.6 19.3 41.1 24.7 57.2 94.1 17.3 111.8 76.4 50.5 60.9 23.5 32.8 30.1 24.5 102.9 41.8 14.4 18.7 33.0 54.7 18.5 25.4 35.7 27.6 37.4 79.6 31.9 53.2 42.0 57.6 42.6 75.9 71.9 52.4 27.4 16.1 132.0 89.6 15.7 49.4 17.5 6.7 32.7 23.2 31.1 92.3 38.3 80.7 27.5 14.6 9.0 54.3 21.5 46.0 30.6 22.7 24.4 67.0 58.7 42.5 52.1 30.7 94.7 48.2 33.1 41.9 34.0 46.7 86.2 33.2 36.8 45.1 44.4 58.8 27.1 29.7 39.8 32.5 26.1 19.2 27.2 50.8 49.4 50.9 53.1 28.8 30.1 16.5 17.4 19.5 20.4 17.9 20.6 20.5 18.7 20.3 19.0 19.6 21.0 40.8 38.5 54.8 27.4 41.7 26.6 86.9 43.0 19.9 42.8 43.1 29.5 26.5 37.1 62.1 57.0 18.8 18.8 67.3 36.4 66.5 65.9 19.1 60.5 89.9 42.4 49.1 17.5 26.1 64.3 23.7 58.1 30.1 96.3 65.9 28.4 30.4 37.3 28.7 33.7 28.8 53.0 46.8 21.7 89.3 15.0 48.1 68.2 69.4 35.6 33.7 40.5 38.1 43.7 40.0 83.0 15.6 45.5 110.0 121.5 70.9 62.9 65.5 33.7 39.5 80.0 65.5 178.7 67.6 14.6 26.7 59.9 49.6 39.0 22.7 86.7 ARHGAP11A KIAA0013 ENSG00000198826 "Rho GTPase activating protein 11A" Q6P4F7 15 32615144-32639941 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 24.2;lymphoid tissue: 26.1" "Cell type enhanced" "Detected in many" "Erythroid cells: 38.7;Extravillous trophoblasts: 23.7;Granulosa cells: 21.1;Plasma cells: 18.6;Spermatocytes: 24.7;Spermatogonia: 22.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040830, HPA066481" Enhanced Approved Nucleoli,Cytosol No Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol Nucleoli "HPA040830: AB_10805830, HPA066481: " "unprognostic (5.00e-2)" "unprognostic (5.57e-2)" "unprognostic (6.10e-2)" "unprognostic (1.97e-1)" "unprognostic (2.93e-1)" "unprognostic (3.41e-2)" "prognostic unfavorable (2.05e-4)" "prognostic unfavorable (8.69e-4)" "unprognostic (4.87e-2)" "unprognostic (7.71e-2)" "prognostic unfavorable (2.92e-5)" "unprognostic (3.43e-2)" "unprognostic (1.07e-12)" "unprognostic (7.37e-2)" "unprognostic (5.23e-1)" "unprognostic (1.54e-2)" "unprognostic (9.64e-2)" 1.7 0.9 2.0 7.9 2.5 24.2 1.7 2.1 2.1 1.5 1.2 7.5 6.1 1.5 1.0 5.3 0.8 1.7 0.7 1.7 1.9 0.6 1.3 1.7 13.5 2.6 3.0 0.6 2.6 1.2 0.7 4.3 2.6 0.6 8.8 0.5 1.2 0.5 0.9 4.4 7.6 4.8 2.5 2.8 3.6 8.6 2.2 26.1 1.3 0.4 14.3 2.8 1.9 3.0 80.8 69.4 73.1 46.2 5.0 13.0 39.6 78.5 50.2 80.0 63.3 52.2 41.5 43.5 23.7 49.9 91.3 56.9 55.3 43.8 110.9 83.5 27.4 132.6 68.9 33.5 2.0 103.8 55.5 4.3 5.5 61.6 50.9 15.2 61.5 94.4 101.0 112.7 95.3 31.7 58.6 39.7 44.6 71.6 44.5 67.8 141.7 38.2 28.4 41.6 64.7 44.5 72.9 46.2 17.6 37.6 63.6 115.8 35.3 102.5 74.1 42.0 87.2 38.3 63.7 123.7 44.4 129.1 91.8 0.1 0.3 0.8 0.5 0.5 0.2 0.3 1.0 0.9 0.4 0.2 0.4 0.5 0.0 0.1 0.1 0.2 0.8 0.3 2.0 2.5 2.1 2.1 1.7 1.9 2.6 3.0 2.6 2.5 2.2 3.0 0.7 0.0 2.3 0.3 4.6 4.8 1.1 2.4 2.2 0.2 1.3 1.7 0.9 4.3 1.9 1.8 0.0 9.8 2.9 6.2 0.0 0.8 4.7 3.8 2.6 2.0 0.0 38.7 1.0 0.8 23.7 3.5 8.6 2.8 0.0 21.1 1.8 2.1 9.5 0.0 0.6 7.8 0.0 6.5 4.2 5.0 0.6 3.5 0.0 1.0 3.9 0.1 2.1 0.5 1.4 0.5 2.9 0.4 18.6 1.4 1.1 0.4 1.4 1.0 6.6 1.4 3.3 24.7 22.6 10.5 2.3 3.1 5.4 2.0 14.1 2.1 ARHGAP17 "FLJ10308, FLJ13219, NADRIN, RICH1, WBP15" ENSG00000140750 "Rho GTPase activating protein 17" Q68EM7 16 24919389-25015666 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041703, HPA075891" Approved Supported "Plasma membrane,Cytosol" NA NA 21000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cytosol" "HPA041703: AB_10794304, HPA075891: " "unprognostic (1.79e-1)" "unprognostic (8.98e-2)" "unprognostic (8.11e-2)" "prognostic favorable (3.59e-4)" "unprognostic (4.42e-2)" "unprognostic (3.49e-2)" "prognostic unfavorable (4.95e-4)" "unprognostic (3.02e-2)" "unprognostic (6.62e-2)" "unprognostic (8.81e-3)" "unprognostic (4.99e-2)" "unprognostic (3.45e-2)" "unprognostic (1.38e-2)" "unprognostic (1.94e-1)" "unprognostic (3.91e-2)" "unprognostic (1.26e-1)" "prognostic unfavorable (3.76e-4)" 46.0 40.5 8.2 15.2 9.8 9.2 37.2 9.2 10.2 29.9 9.6 32.7 11.3 28.9 7.9 33.6 28.6 11.9 48.1 7.9 9.2 25.9 22.9 31.8 24.9 10.6 9.5 24.8 24.1 9.3 30.3 15.3 10.4 23.6 12.2 2.3 21.3 7.9 41.0 34.3 39.2 11.6 8.7 66.8 28.9 25.5 9.7 12.0 28.2 11.1 20.9 25.6 29.8 11.6 28.5 16.7 21.9 23.1 22.0 23.0 23.7 18.1 19.3 20.9 20.4 25.9 11.5 13.0 12.0 36.4 19.9 7.7 21.8 12.8 22.2 20.0 26.1 10.8 37.8 43.3 25.0 15.5 10.7 29.4 7.7 22.6 16.3 15.0 35.7 11.7 14.3 0.0 23.6 20.8 14.3 19.8 25.2 8.1 13.7 68.1 17.9 5.2 25.9 6.4 14.6 14.5 18.6 20.5 8.2 17.5 11.1 40.2 46.7 15.5 11.9 35.6 15.1 13.0 17.3 7.5 19.1 22.6 14.1 5.6 9.7 9.0 6.3 17.5 5.7 25.3 5.5 6.3 14.6 22.8 6.2 6.1 4.8 6.2 15.8 25.9 8.0 8.1 8.2 9.8 9.2 10.2 7.9 9.2 10.6 9.5 10.4 8.7 9.7 11.6 33.8 9.6 11.0 26.8 46.3 14.5 6.8 8.9 14.2 6.4 11.0 9.7 24.9 7.2 9.1 5.5 10.4 11.1 36.3 49.5 3.9 13.3 6.3 30.6 21.8 32.3 21.0 16.2 28.8 16.0 18.9 16.0 15.3 66.4 7.0 16.9 26.7 6.8 27.1 10.1 33.0 21.8 8.2 30.3 21.7 10.8 13.4 25.2 16.0 59.0 22.8 6.4 14.4 40.2 68.9 17.6 27.2 11.7 11.5 11.1 35.4 5.0 8.5 7.5 26.3 15.5 43.8 7.0 11.7 24.7 24.0 15.7 21.1 15.9 19.7 12.2 ARHGAP26 "GRAF, KIAA0621, OPHN1L, OPHN1L1" ENSG00000145819 "Rho GTPase activating protein 26" Q9UNA1 5 142770377-143229011 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Astrocytes: 237.3;Excitatory neurons: 611.6;Inhibitory neurons: 261.5;Late spermatids: 153.3;Microglial cells: 326.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "neutrophil: 24.7;NK-cell: 9.8" "Group enriched" "Detected in many" 4 "granulocytes: 24.7;NK-cells: 9.8" "Cell line enhanced" "Detected in many" "Karpas-707: 85.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035106, HPA035107" Enhanced Approved Cytosol NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 2: Karpas-707 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA035106: AB_2674465, HPA035107: AB_10669855" "prognostic favorable (2.05e-4)" "prognostic favorable (1.36e-4)" "prognostic favorable (6.95e-4)" "prognostic favorable (5.93e-6)" "unprognostic (1.19e-1)" "unprognostic (1.93e-2)" "unprognostic (4.19e-3)" "unprognostic (5.93e-2)" "unprognostic (2.22e-1)" "unprognostic (9.43e-3)" "unprognostic (7.19e-3)" "unprognostic (8.65e-2)" "unprognostic (3.21e-3)" "unprognostic (5.67e-2)" "unprognostic (2.70e-2)" "unprognostic (2.95e-2)" "prognostic favorable (2.88e-6)" 11.0 4.5 10.9 17.7 6.5 36.4 11.3 19.3 17.0 11.9 0.6 12.9 12.0 7.7 9.1 6.4 15.5 14.2 15.0 10.8 3.4 8.9 6.8 19.0 6.4 0.5 2.7 3.0 4.9 3.9 12.2 20.9 0.3 7.4 12.7 17.2 12.8 4.2 12.6 7.4 11.3 9.7 2.3 16.7 15.2 15.4 10.1 13.8 8.3 10.5 12.2 12.2 5.8 9.9 16.4 29.1 8.0 7.6 12.3 12.7 12.4 2.2 2.4 7.6 12.1 44.9 33.0 2.0 16.1 4.9 21.5 7.5 4.1 15.3 8.7 33.8 4.6 0.1 5.3 26.9 7.8 22.6 2.9 4.7 23.0 12.8 31.0 5.6 10.2 9.9 0.6 85.4 2.4 2.3 12.9 9.2 4.3 23.2 7.7 5.2 12.5 36.5 20.4 25.6 3.4 4.7 3.8 4.4 7.1 6.5 2.4 6.2 21.0 4.1 5.8 0.4 8.1 4.0 14.0 0.4 10.7 21.3 5.6 4.0 3.9 2.3 3.8 2.5 1.7 0.5 0.8 2.4 3.0 0.4 0.3 1.1 24.7 9.8 1.6 0.7 0.3 1.8 10.9 6.5 19.3 17.0 10.8 3.4 0.5 2.7 0.3 2.3 10.1 9.9 39.4 16.0 22.5 237.3 5.8 6.9 13.8 13.2 5.7 15.9 20.7 17.0 37.6 21.5 14.1 0.0 8.4 1.3 41.6 38.7 0.0 17.9 77.2 17.9 4.0 32.5 3.6 11.8 611.6 21.1 0.6 13.6 39.8 55.6 26.6 6.4 40.0 6.5 26.4 75.7 261.5 26.4 0.0 48.0 44.9 153.3 6.5 51.6 10.6 326.0 47.3 7.5 40.2 30.7 29.8 21.1 27.8 14.3 14.5 29.3 27.9 5.8 16.1 52.6 46.0 27.6 17.7 2.6 8.7 7.5 5.5 1.9 29.3 50.5 26.8 36.2 ARHGAP31 CDGAP ENSG00000031081 "Rho GTPase activating protein 31" Q2M1Z3 3 119294383-119420714 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 47.8;Astrocytes: 123.1;Endothelial cells: 46.9;Langerhans cells: 54.1;Microglial cells: 125.5;Oligodendrocyte precursor cells: 159.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 6.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 35.0;TIME: 38.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036380 Approved NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" "HPA036380: AB_10673129" "unprognostic (2.22e-2)" "unprognostic (1.93e-2)" "unprognostic (9.90e-2)" "unprognostic (1.48e-1)" "unprognostic (1.09e-2)" "unprognostic (1.11e-1)" "unprognostic (8.75e-3)" "unprognostic (3.22e-2)" "unprognostic (2.57e-1)" "unprognostic (7.18e-3)" "unprognostic (5.86e-2)" "unprognostic (1.30e-1)" "prognostic favorable (8.45e-4)" "unprognostic (3.57e-2)" "unprognostic (6.32e-2)" "unprognostic (1.38e-1)" "unprognostic (7.79e-3)" 17.0 2.1 8.3 7.6 9.3 0.8 9.0 10.1 8.3 6.0 1.1 5.4 3.0 6.2 3.1 5.9 5.1 8.6 13.0 8.3 8.9 4.9 3.6 19.5 5.6 11.6 10.4 6.1 2.9 4.0 2.1 11.2 9.4 3.0 5.4 1.5 2.8 3.4 4.2 6.4 4.7 11.8 9.0 7.1 3.2 1.3 10.8 6.9 12.7 9.2 6.8 8.1 3.8 9.9 0.4 2.5 6.2 12.2 3.5 2.9 1.9 7.5 8.6 5.8 4.2 0.1 0.5 0.1 8.7 19.5 10.0 0.2 5.9 1.9 6.7 11.0 0.8 1.7 0.8 0.0 5.8 0.4 7.0 7.8 0.2 15.1 1.7 4.5 35.0 1.2 0.0 3.0 13.1 0.2 0.1 0.3 2.1 0.0 7.6 0.0 2.9 0.0 1.7 0.0 0.0 22.7 3.8 0.0 15.6 3.3 0.7 0.6 38.5 16.0 6.4 2.0 5.9 5.1 5.6 6.2 10.9 5.6 16.4 0.0 2.6 0.0 0.4 2.8 0.8 1.6 0.3 0.5 6.0 0.6 0.3 0.2 0.0 1.1 1.1 5.2 0.8 1.2 8.3 9.3 10.1 8.3 8.3 8.9 11.6 10.4 9.4 9.0 10.8 9.9 47.8 19.2 24.6 123.1 7.3 5.2 0.7 3.1 1.8 0.6 0.5 1.7 16.0 1.5 3.1 0.0 0.0 1.2 9.8 0.2 0.0 2.1 0.4 0.4 2.1 46.9 0.0 7.4 3.4 2.0 10.3 7.3 0.0 0.4 9.5 8.4 30.7 0.6 10.1 0.0 18.4 3.9 0.0 14.5 54.1 0.7 2.8 16.7 10.6 125.5 13.8 3.9 4.1 159.8 0.9 1.9 0.3 2.6 4.9 1.1 0.0 2.1 1.4 0.4 0.0 2.5 11.3 0.3 0.7 1.3 5.1 1.0 3.7 3.3 0.4 0.7 ARHGEF10 "Gef10, KIAA0294" ENSG00000104728 "Rho guanine nucleotide exchange factor 10" O15013 8 1823926-1958641 "Disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 90.1;Oligodendrocyte precursor cells: 69.9;Oligodendrocytes: 158.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024649 Approved Approved Nucleoplasm NA NA "Cluster 71: Testis - DNA repair" "Cluster 17: WM-115 - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA024649: AB_1845002" "unprognostic (2.51e-1)" "unprognostic (3.60e-2)" "unprognostic (2.39e-1)" "unprognostic (1.08e-2)" "unprognostic (1.02e-1)" "unprognostic (3.57e-1)" "unprognostic (1.44e-1)" "unprognostic (7.27e-2)" "unprognostic (1.69e-1)" "unprognostic (1.07e-1)" "unprognostic (2.43e-2)" "unprognostic (9.29e-2)" "unprognostic (3.37e-2)" "unprognostic (1.81e-2)" "unprognostic (4.42e-1)" "unprognostic (3.18e-2)" "unprognostic (4.46e-2)" 19.2 10.1 9.3 2.3 9.9 0.4 15.2 9.3 9.6 14.7 9.3 19.1 0.5 18.7 2.7 5.5 15.0 1.9 18.3 9.0 8.9 12.4 3.4 27.9 1.6 9.7 9.8 13.5 6.6 1.1 7.3 3.0 10.3 12.8 1.6 1.9 12.1 3.1 4.0 13.3 9.3 4.7 8.8 6.9 14.2 24.3 9.1 2.1 12.9 1.1 1.1 12.3 13.4 11.7 7.1 7.6 7.7 4.0 6.8 7.4 1.9 9.4 6.9 6.5 7.8 2.5 3.2 0.0 1.0 11.7 11.1 5.3 8.4 10.9 8.8 0.0 3.0 3.2 8.6 0.0 6.0 0.0 2.1 6.5 6.2 7.7 6.1 10.0 11.8 2.5 3.1 0.0 8.0 3.8 5.8 1.1 6.6 5.3 4.2 0.3 8.6 0.0 6.2 2.7 1.5 1.6 5.7 0.2 5.3 9.4 3.1 2.1 13.2 5.9 3.8 0.1 8.4 0.0 2.9 0.1 6.0 8.4 11.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 9.3 9.9 9.3 9.6 9.0 8.9 9.7 9.8 10.3 8.8 9.1 11.7 11.7 3.2 4.1 90.1 0.9 38.4 13.4 8.1 5.7 7.7 7.8 6.3 13.3 15.7 5.0 7.3 10.4 0.6 2.6 1.4 0.0 7.5 17.8 3.3 11.4 27.7 1.2 3.6 17.3 2.0 1.6 30.0 4.1 6.9 0.0 11.3 13.9 1.2 1.7 21.9 16.3 4.5 8.2 1.6 9.4 20.5 35.1 2.1 23.2 50.6 0.3 10.1 4.1 69.9 158.9 12.4 0.3 26.4 2.3 22.6 0.7 0.8 2.8 9.2 0.0 22.6 14.2 54.9 38.3 1.4 15.2 0.3 2.1 7.7 2.4 6.3 ARHGEF18 "KIAA0521, MGC15913, P114-RhoGEF, p114RhoGEF" ENSG00000104880 "Rho/Rac guanine nucleotide exchange factor 18" Q6ZSZ5 19 7348937-7472485 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 17.0;Excitatory neurons: 22.2;Inhibitory neurons: 18.0;Microglial cells: 14.0;Oligodendrocyte precursor cells: 18.1;Oligodendrocytes: 30.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042689, HPA049151, HPA071867" Approved Enhanced Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA042689: AB_10794385, HPA049151: AB_2680654, HPA071867: AB_2686466" "unprognostic (2.55e-1)" "unprognostic (1.31e-2)" "unprognostic (1.57e-1)" "unprognostic (6.01e-2)" "unprognostic (1.65e-2)" "prognostic favorable (4.21e-4)" "unprognostic (1.13e-1)" "unprognostic (1.52e-3)" "unprognostic (3.56e-1)" "unprognostic (2.36e-1)" "unprognostic (1.40e-1)" "unprognostic (8.26e-2)" "prognostic favorable (3.11e-5)" "unprognostic (1.08e-1)" "unprognostic (2.21e-1)" "unprognostic (1.42e-1)" "unprognostic (3.79e-3)" 8.2 15.9 10.4 20.0 13.3 27.1 8.1 9.7 12.1 12.2 7.0 22.1 13.3 16.8 3.1 19.9 9.7 10.7 7.1 9.8 8.8 24.1 13.1 14.6 29.8 12.1 13.0 10.1 21.0 11.2 15.8 7.8 10.8 14.2 7.7 5.0 11.0 7.3 5.3 13.8 31.1 13.9 9.5 35.9 22.6 8.9 12.2 33.1 10.8 3.0 17.5 14.0 12.1 15.3 31.2 17.9 10.2 13.9 9.4 7.8 30.8 13.4 12.9 20.5 20.8 24.5 17.4 62.9 29.4 15.2 15.3 24.6 12.7 29.7 11.8 37.6 16.1 15.5 11.7 16.4 22.1 31.2 30.4 12.8 20.2 19.7 16.3 10.1 11.2 20.2 13.4 14.7 21.3 11.0 36.0 26.8 16.0 16.9 29.2 42.2 17.6 17.2 9.0 34.6 9.8 13.7 16.4 16.1 18.8 9.6 17.4 36.4 21.9 16.8 20.1 25.9 17.2 35.6 23.2 40.2 16.7 27.5 15.1 6.4 3.7 23.0 3.9 4.5 4.0 8.8 5.3 4.3 2.3 12.4 5.4 4.1 12.5 0.9 6.9 2.8 3.9 3.5 10.4 13.3 9.7 12.1 9.8 8.8 12.1 13.0 10.8 9.5 12.2 15.3 0.2 0.0 1.1 17.0 2.2 2.9 0.0 6.5 2.8 0.2 0.4 0.1 0.2 0.0 4.3 0.0 4.2 0.1 0.3 0.5 0.0 0.3 0.1 2.4 0.8 0.5 1.8 3.0 22.2 0.4 0.1 1.1 6.1 2.9 0.0 0.5 0.0 0.0 0.2 0.0 18.0 0.0 4.1 0.3 2.1 0.1 0.0 1.6 1.8 14.0 0.7 0.0 0.0 18.1 30.5 0.6 2.3 0.0 4.3 0.0 0.7 0.1 9.3 0.4 0.0 0.1 1.2 0.0 0.0 3.9 3.8 0.0 1.6 0.0 0.0 0.3 ARIH2 TRIAD1 ENSG00000177479 "Ariadne RBR E3 ubiquitin protein ligase 2" O95376 3 48918821-48986382 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA067381, HPA069715, HPA070963" Enhanced Nucleoplasm NA NA "Cluster 44: Non-specific - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "HPA067381: AB_2685827, HPA069715: AB_2686182, HPA070963: AB_2686329" "unprognostic (7.24e-2)" "unprognostic (1.08e-1)" "unprognostic (1.26e-1)" "unprognostic (2.74e-1)" "unprognostic (2.55e-1)" "unprognostic (4.79e-3)" "prognostic unfavorable (1.70e-4)" "unprognostic (1.90e-2)" "unprognostic (4.01e-2)" "unprognostic (5.01e-2)" "prognostic favorable (7.31e-4)" "unprognostic (5.01e-3)" "prognostic favorable (6.60e-4)" "unprognostic (1.15e-1)" "unprognostic (7.04e-2)" "unprognostic (1.27e-2)" "unprognostic (1.39e-2)" 20.6 22.9 21.4 16.0 24.5 23.0 19.8 24.2 23.7 21.4 24.7 29.4 11.7 24.5 33.8 19.5 21.3 15.0 53.9 21.3 23.4 22.7 21.3 19.7 20.7 22.9 22.9 20.7 24.1 24.4 26.0 18.4 23.8 23.1 17.7 32.4 18.6 21.9 100.4 16.5 21.2 24.4 22.0 24.3 22.5 27.0 22.8 26.1 22.0 79.6 21.4 23.6 17.4 27.7 40.4 39.6 37.6 53.2 54.3 29.7 52.4 46.3 53.5 56.5 62.1 42.0 35.0 84.1 21.4 49.8 82.0 23.5 77.9 47.2 68.7 57.0 48.1 85.3 51.7 34.5 48.9 63.4 39.5 31.9 70.2 70.9 94.9 32.2 43.1 38.3 68.4 54.6 50.7 27.8 65.4 25.8 64.3 43.3 59.5 23.5 42.8 70.2 32.9 54.1 16.4 44.8 47.7 56.1 45.0 44.1 28.6 43.8 41.4 34.1 49.4 52.5 74.0 72.8 148.1 103.3 37.3 51.9 43.7 53.1 34.6 39.9 44.2 32.2 30.5 28.8 28.2 37.1 32.3 34.2 29.2 37.3 25.6 25.8 20.9 29.9 35.5 39.3 21.4 24.5 24.2 23.7 21.3 23.4 22.9 22.9 23.8 22.0 22.8 27.7 37.0 35.3 31.4 54.9 50.2 50.9 51.5 27.3 68.3 57.0 35.5 35.3 74.6 32.9 44.0 29.5 87.6 36.4 76.0 31.3 29.4 33.8 15.3 33.5 48.3 38.4 16.7 76.2 50.0 43.2 36.2 40.1 42.3 38.1 45.5 42.3 28.5 44.6 26.6 57.2 59.1 26.2 14.2 32.8 35.7 11.3 41.7 44.6 30.2 38.4 45.2 42.2 95.8 42.3 128.6 42.1 23.0 43.2 85.0 78.9 20.8 34.3 30.6 82.5 26.3 51.5 48.6 165.7 89.7 59.4 54.0 53.4 66.8 37.7 31.6 67.0 ARL2 ARFL2 ENSG00000213465 "ADP ribosylation factor like GTPase 2" P36404 11 65014160-65022184 "FDA approved drug targets, Predicted intracellular proteins" "Cell cycle" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 430.8;Late spermatids: 1125.1;Proximal tubular cells: 505.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044610 Supported Approved "Nucleoplasm,Nucleoli,Golgi apparatus,Focal adhesion sites,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "Nucleoli, Golgi apparatus, Focal adhesion sites, Cytosol" "HPA044610: AB_10964207" "unprognostic (9.23e-2)" "unprognostic (3.66e-1)" "unprognostic (1.43e-1)" "prognostic unfavorable (4.58e-4)" "unprognostic (1.61e-1)" "unprognostic (5.08e-2)" "unprognostic (1.07e-3)" "unprognostic (2.34e-1)" "unprognostic (9.85e-3)" "unprognostic (6.43e-2)" "unprognostic (6.87e-3)" "prognostic favorable (7.70e-4)" "unprognostic (2.15e-2)" "unprognostic (1.85e-1)" "unprognostic (1.60e-1)" "unprognostic (4.39e-1)" "unprognostic (1.24e-2)" 124.8 93.7 161.5 40.6 190.2 51.3 112.0 172.4 200.2 106.3 132.3 123.1 52.7 121.2 28.2 67.2 94.6 48.0 169.1 157.0 168.7 138.5 22.5 90.4 37.7 171.5 167.9 95.7 75.3 65.3 68.5 56.1 167.2 84.7 32.9 43.5 67.9 66.6 214.2 95.8 73.4 60.9 171.4 63.4 85.2 116.1 167.4 33.5 85.7 158.1 29.0 112.2 93.5 184.4 162.0 257.0 76.5 115.8 207.4 156.5 70.5 82.5 181.7 111.2 109.1 72.8 110.0 62.1 144.5 112.7 168.1 101.4 82.9 140.0 53.1 65.5 130.6 61.9 109.2 111.9 157.8 77.9 54.9 123.7 114.6 92.6 204.4 160.5 150.4 74.0 152.8 110.1 76.4 194.1 63.1 174.5 120.3 77.7 208.6 33.4 81.6 152.9 120.9 70.6 143.3 79.3 66.4 67.6 225.8 74.4 72.3 94.3 109.2 205.9 68.6 164.7 82.1 37.9 57.6 38.5 97.2 112.5 171.3 46.5 78.2 72.5 120.4 80.2 130.9 163.1 110.0 116.9 101.7 149.0 123.5 137.2 10.2 83.3 48.2 140.1 79.0 136.9 161.5 190.2 172.4 200.2 157.0 168.7 171.5 167.9 167.2 171.4 167.4 184.4 179.1 22.4 43.6 0.0 42.7 81.4 94.4 118.4 63.7 70.2 66.8 83.9 103.2 51.5 66.4 82.8 29.2 179.7 40.0 110.0 268.0 142.0 430.8 42.2 59.0 148.0 83.3 69.4 0.0 76.0 193.5 107.0 29.6 50.7 95.7 71.5 137.4 19.7 98.3 69.0 0.0 68.4 83.4 49.7 73.5 1125.1 71.7 49.5 177.9 0.0 100.6 208.4 55.6 0.0 0.0 68.3 115.7 71.1 16.5 79.9 162.4 505.5 47.0 48.9 65.7 74.2 109.7 126.5 79.4 56.3 82.8 107.3 40.0 65.7 98.0 75.9 ARMC12 "C6orf81, FLJ25390" ENSG00000157343 "Armadillo repeat containing 12" Q5T9G4 6 35737032-35749079 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "testis: 64.2" "Group enriched" "Detected in some" 96 "Early spermatids: 503.3;Late spermatids: 1116.3" "Cancer enhanced" "Detected in some" "glioma: 1.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 4.9;HSkMC: 6.1;MOLT-4: 4.8;U-698: 5.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA030895, HPA075457, HPA075777" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Plasma membrane" "HPA030895: AB_10602114, HPA075457: , HPA075777: " "unprognostic (1.94e-4)" "unprognostic (2.21e-1)" "unprognostic (3.24e-1)" "unprognostic (1.32e-2)" "unprognostic (2.34e-1)" "unprognostic (1.19e-1)" "unprognostic (2.52e-1)" "unprognostic (2.12e-1)" "unprognostic (4.48e-1)" "unprognostic (3.52e-2)" "unprognostic (6.36e-4)" "unprognostic (8.99e-2)" "unprognostic (1.17e-12)" "unprognostic (6.53e-2)" "unprognostic (1.82e-1)" "unprognostic (1.49e-1)" "unprognostic (2.09e-1)" 1.6 1.7 4.4 0.6 4.4 0.9 1.5 4.0 5.3 2.5 5.1 1.5 0.0 1.7 5.8 0.8 2.8 0.7 0.7 4.3 4.5 1.5 4.5 1.2 1.3 4.6 5.1 3.0 1.3 0.5 11.2 0.2 4.6 3.6 0.3 1.3 0.6 0.8 1.9 1.1 1.7 0.7 4.3 2.8 1.2 64.2 4.3 3.0 2.4 0.5 0.7 1.1 1.7 4.5 0.0 0.3 2.1 2.7 4.9 2.3 0.0 0.1 0.1 0.2 0.2 0.0 0.1 0.5 0.1 0.1 0.8 0.1 0.6 0.1 0.1 1.2 0.6 0.3 0.1 0.0 2.4 0.0 0.0 6.1 1.5 0.1 0.9 2.5 0.5 2.0 0.0 3.2 0.8 0.3 4.8 0.6 0.4 0.0 0.1 2.2 0.0 0.0 0.5 0.0 0.6 2.0 0.0 0.0 0.4 1.0 1.4 0.2 0.0 0.4 0.2 0.1 0.0 0.7 0.2 5.4 0.2 2.8 0.2 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.3 0.1 0.2 0.0 0.2 0.9 0.0 0.0 0.0 0.8 0.0 0.1 4.4 4.4 4.0 5.3 4.3 4.5 4.6 5.1 4.6 4.3 4.3 4.5 0.8 0.0 0.0 4.6 0.1 0.9 1.9 0.2 1.2 0.0 0.3 0.4 0.2 1.5 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 503.3 0.4 0.4 0.8 0.0 0.4 0.3 0.0 0.0 0.6 0.0 0.3 0.0 2.4 0.4 2.8 0.0 0.0 0.5 0.2 0.0 1.2 0.8 1116.3 8.4 1.3 0.0 0.0 0.1 0.8 0.0 0.5 0.3 0.0 0.0 4.1 0.0 0.7 0.2 0.3 0.2 0.2 0.0 0.5 0.4 8.1 6.0 0.7 0.1 0.0 0.3 0.2 0.2 0.4 ARMC2 "bA787I22.1, DKFZp434P0714" ENSG00000118690 "Armadillo repeat containing 2" Q8NEN0 6 108848416-108974476 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 33.4" "Cell type enhanced" "Detected in many" "Astrocytes: 80.0;Early spermatids: 117.7;Excitatory neurons: 86.1;Inhibitory neurons: 69.3;Late spermatids: 145.3;Respiratory ciliated cells: 61.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025809, HPA053696" Enhanced Approved Nucleoplasm NA NA "Cluster 17: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "HPA025809: AB_1845032, HPA053696: AB_2682233" "unprognostic (4.42e-2)" "unprognostic (9.64e-2)" "unprognostic (1.12e-1)" "unprognostic (2.09e-2)" "unprognostic (1.45e-2)" "unprognostic (2.11e-1)" "unprognostic (4.00e-4)" "unprognostic (1.13e-2)" "unprognostic (3.74e-2)" "unprognostic (5.71e-2)" "unprognostic (5.19e-5)" "unprognostic (7.55e-2)" "unprognostic (1.55e-3)" "unprognostic (9.38e-2)" "unprognostic (6.44e-2)" "unprognostic (4.65e-2)" "unprognostic (2.28e-1)" 5.3 3.8 3.8 3.9 7.8 8.8 7.0 0.9 6.8 6.6 31.8 2.9 1.8 7.5 7.6 3.4 20.4 5.2 9.3 3.0 2.3 3.6 2.6 8.6 4.2 2.7 5.9 5.4 2.4 9.4 6.7 6.9 1.2 3.9 4.6 26.7 3.4 4.7 4.0 5.2 3.4 4.1 1.1 5.9 5.0 33.4 7.6 3.8 10.6 1.3 4.2 2.4 2.7 3.6 3.5 2.1 10.1 6.5 4.9 5.9 2.2 2.1 2.9 5.3 7.0 3.2 3.0 5.5 2.6 3.4 8.1 3.0 5.6 4.2 9.1 1.5 4.9 5.1 5.2 3.4 2.6 8.0 2.2 6.8 5.8 6.1 1.7 7.1 5.0 16.6 2.2 8.4 5.5 2.7 7.0 7.3 3.2 3.4 2.6 7.8 8.3 4.3 4.9 4.1 14.0 5.2 7.3 1.8 5.1 5.6 3.7 4.1 2.5 4.4 2.3 3.8 2.9 3.8 5.5 4.7 7.6 5.5 5.6 3.7 2.1 0.6 2.0 3.0 1.8 0.8 1.5 2.2 1.7 1.9 0.9 2.2 6.0 2.9 2.4 2.8 4.7 1.0 3.8 7.8 0.9 6.8 3.0 2.3 2.7 5.9 1.2 1.1 7.6 3.6 2.0 9.6 3.7 80.0 3.4 1.0 1.1 1.9 0.6 2.0 1.2 1.5 6.8 1.5 10.9 0.0 0.0 1.5 2.9 0.3 0.0 1.2 117.7 33.0 2.7 2.2 1.8 2.1 86.1 1.0 2.1 3.0 1.5 1.8 0.0 2.8 0.7 0.3 3.9 1.7 69.3 0.4 4.1 4.4 0.4 145.3 6.8 3.1 5.4 11.2 0.5 1.7 3.1 35.7 24.4 0.7 0.0 10.1 5.9 0.6 0.4 1.8 61.8 4.9 0.0 4.2 4.2 41.5 6.3 1.9 1.4 0.5 5.1 2.5 0.6 0.7 ARMH4 "C14orf37, UT2" ENSG00000139971 "Armadillo like helical domain containing 4" Q86TY3 14 57999735-58298139 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 12.8;kidney: 8.3" "Cell type enhanced" "Detected in some" "Adipocytes: 15.8;Collecting duct cells: 12.9;Endometrial ciliated cells: 10.2;Endometrial stromal cells: 7.7;Granulosa cells: 26.0;Theca cells: 44.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 9.7;AN3-CA: 6.1;fHDF/TERT166: 10.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001580, HPA001789" Enhanced Approved "Plasma membrane" NA NA 1800000 "Cluster 21: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 52: Non-specific - Transcription" "Plasma membrane" "HPA001580: AB_2666366, HPA001789: AB_1078328" "unprognostic (2.56e-2)" "unprognostic (2.04e-2)" "unprognostic (1.20e-3)" "unprognostic (8.56e-2)" "unprognostic (1.15e-1)" "unprognostic (6.97e-3)" "unprognostic (1.94e-1)" "unprognostic (7.84e-3)" "unprognostic (2.66e-1)" "unprognostic (2.32e-1)" "unprognostic (2.42e-1)" "unprognostic (1.01e-1)" "unprognostic (3.87e-8)" "unprognostic (5.22e-6)" "unprognostic (4.93e-2)" "unprognostic (8.74e-4)" "unprognostic (3.01e-4)" 1.2 2.5 2.3 0.6 3.6 0.7 0.8 8.5 3.5 1.8 0.0 0.7 0.5 3.0 1.8 0.8 2.1 1.8 3.1 2.6 2.1 8.3 0.8 0.7 0.4 11.5 5.1 4.3 1.0 3.6 1.3 0.4 12.8 1.6 1.0 1.2 0.7 1.4 0.2 1.0 0.7 2.3 1.0 0.5 1.4 2.2 1.6 0.2 1.5 1.9 0.3 1.2 0.9 0.7 0.0 0.0 9.7 6.1 4.7 1.7 0.0 1.9 1.5 0.3 0.3 0.5 0.1 0.0 0.6 10.8 1.2 0.0 2.9 0.0 0.4 0.1 1.0 0.0 0.0 0.5 0.2 0.0 4.8 1.8 0.0 0.2 0.2 2.7 0.5 0.8 0.1 0.3 1.2 0.3 0.0 0.0 4.5 0.0 2.0 1.4 0.3 2.5 3.9 0.3 1.1 0.0 0.1 0.0 0.3 2.7 0.2 0.2 0.1 1.3 3.5 0.5 2.6 0.3 0.2 0.0 3.0 0.3 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 3.6 8.5 3.5 2.6 2.1 11.5 5.1 12.8 1.0 1.6 0.7 15.8 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.4 1.4 0.0 0.0 0.0 12.9 0.0 0.2 0.7 0.0 0.0 2.1 0.0 10.2 7.7 2.3 0.0 0.0 0.0 1.3 0.4 3.0 0.0 2.4 0.0 26.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.0 0.0 2.6 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.3 0.3 44.5 0.0 0.0 ARNT2 "bHLHe1, KIAA0307" ENSG00000172379 "Aryl hydrocarbon receptor nuclear translocator 2" Q9HBZ2 15 80404350-80597933 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 128.0" "Group enriched" "Detected in many" 4 "Astrocytes: 209.6;Excitatory neurons: 204.7;Inhibitory neurons: 301.5;Microglial cells: 98.4;Oligodendrocyte precursor cells: 232.7;Oligodendrocytes: 136.9" "Cancer enhanced" "Detected in all" "glioma: 27.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 28.4;BJ hTERT+ SV40 Large T+ RasG12V: 28.2;hTERT-RPE1: 29.7;LHCN-M2: 26.0;SK-MEL-30: 30.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001056, CAB005081" Enhanced Supported Nucleoplasm NA NA "Cluster 65: Brain - Ion transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "CAB005081: AB_2243005, HPA001056: AB_1845042" "unprognostic (2.04e-3)" "unprognostic (8.32e-2)" "unprognostic (2.10e-1)" "unprognostic (1.95e-1)" "unprognostic (1.11e-1)" "unprognostic (5.65e-2)" "unprognostic (2.61e-2)" "unprognostic (1.48e-1)" "unprognostic (2.74e-2)" "unprognostic (3.00e-1)" "prognostic favorable (1.46e-6)" "unprognostic (2.20e-1)" "prognostic favorable (7.51e-4)" "unprognostic (2.53e-1)" "unprognostic (2.31e-1)" "unprognostic (3.39e-1)" "unprognostic (3.62e-2)" 2.2 2.1 94.4 2.1 100.6 0.4 1.4 47.8 111.7 5.6 29.8 5.8 1.7 5.9 8.2 2.0 5.3 2.5 4.1 128.0 64.2 21.7 0.4 5.0 2.3 61.8 70.5 10.7 3.4 6.4 11.5 1.1 53.6 5.5 2.1 8.1 1.2 5.0 9.7 2.1 2.7 3.9 60.2 3.5 4.1 9.9 84.0 2.2 7.0 6.0 3.0 4.3 2.0 66.7 0.4 16.1 28.4 0.0 0.1 3.6 0.1 12.2 17.3 13.9 28.2 0.0 0.0 0.0 3.0 14.7 7.2 0.4 10.5 0.6 17.7 0.0 2.9 0.5 0.0 1.0 0.9 0.0 7.2 13.2 0.5 6.1 0.3 29.7 0.0 0.0 0.0 0.1 26.0 14.0 0.0 0.0 5.7 0.0 0.2 0.0 0.3 0.0 6.0 20.5 14.9 20.6 1.5 0.2 30.8 1.8 0.6 0.0 0.0 22.2 4.4 0.6 14.7 0.0 0.0 0.0 8.4 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 94.4 100.6 47.8 111.7 128.0 64.2 61.8 70.5 53.6 60.2 84.0 66.7 0.1 0.0 2.3 209.6 0.0 1.3 1.2 1.5 4.0 17.0 3.2 3.4 7.6 2.8 4.7 3.7 8.4 0.2 0.1 0.2 13.7 6.0 36.7 8.5 2.7 1.8 22.9 0.0 204.7 0.2 3.6 2.7 3.1 4.4 2.5 5.7 0.4 0.0 0.2 1.7 301.5 2.6 8.2 0.0 1.6 39.8 0.6 0.4 7.2 98.4 0.1 5.9 2.1 232.7 136.9 2.4 2.3 3.0 0.0 2.2 0.3 1.0 1.6 9.3 6.6 2.6 2.5 2.1 3.0 0.5 0.3 2.7 0.6 1.9 1.3 1.4 ASB5 ENSG00000164122 "Ankyrin repeat and SOCS box containing 5" Q8WWX0 4 176213673-176277571 "Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "skeletal muscle: 217.2;tongue: 67.0" "Cell type enhanced" "Detected in some" "Early spermatids: 52.7;Late spermatids: 293.6;Skeletal myocytes: 79.6" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.5;prostate cancer: 1.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 16 "LHCN-M2: 1184.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA028870 Approved "Plasma membrane" NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 31: Spermatids - Spermatogenesis" "Plasma membrane" "HPA028870: AB_10611679" "unprognostic (1.76e-1)" "prognostic unfavorable (5.67e-4)" "unprognostic (1.90e-1)" "unprognostic (7.38e-2)" "unprognostic (1.32e-1)" "unprognostic (1.06e-2)" "unprognostic (4.28e-2)" "unprognostic (1.65e-1)" "unprognostic (6.80e-3)" 0.1 0.0 0.4 0.9 0.5 0.0 0.0 1.3 1.0 1.0 0.2 11.1 0.3 0.6 0.1 10.5 0.1 1.2 3.9 0.5 0.4 0.7 0.0 0.2 0.0 0.9 1.5 0.0 0.0 0.1 0.4 0.0 0.8 12.9 3.3 0.0 23.9 0.3 217.2 0.2 1.2 2.5 0.8 0.0 4.7 7.3 0.5 0.1 0.0 67.0 0.0 19.2 0.9 1.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 29.1 0.0 25.9 54.7 0.0 0.1 0.0 0.0 0.0 2.5 0.0 0.0 0.0 61.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1184.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 74.6 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 1.3 1.0 0.5 0.4 0.9 1.5 0.8 0.8 0.5 1.1 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 52.7 0.0 0.0 0.3 0.0 0.0 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 293.6 1.2 0.3 0.0 0.0 0.0 0.0 0.0 11.6 0.8 0.0 0.0 1.2 0.0 0.1 0.0 0.3 0.0 0.0 0.0 79.6 0.6 0.9 1.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 ASB6 ENSG00000148331 "Ankyrin repeat and SOCS box containing 6" Q9NWX5 9 129634604-129642169 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004341 Approved NA NA "Cluster 15: NK-cells - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 6: Erythroid cells - Oxygen transport" "HPA004341: AB_1845070" "unprognostic (1.60e-2)" "unprognostic (7.57e-2)" "prognostic unfavorable (1.06e-5)" "unprognostic (9.29e-2)" "unprognostic (1.27e-1)" "unprognostic (6.05e-2)" "prognostic unfavorable (2.40e-5)" "unprognostic (5.61e-2)" "unprognostic (1.99e-1)" "unprognostic (1.34e-2)" "unprognostic (7.68e-2)" "unprognostic (3.38e-3)" "unprognostic (1.95e-1)" "unprognostic (2.07e-2)" "unprognostic (3.74e-2)" "unprognostic (1.71e-1)" "unprognostic (8.00e-2)" 12.3 21.9 16.0 8.7 16.0 26.9 11.5 15.4 17.8 13.5 16.3 12.1 7.5 13.1 6.2 17.3 13.0 6.2 11.5 16.9 13.6 17.5 11.9 10.8 11.5 16.9 15.3 10.7 15.5 9.1 14.1 7.3 15.5 13.9 5.4 4.4 14.2 8.6 9.8 22.2 13.1 6.2 15.0 19.3 16.2 14.0 15.4 11.2 12.1 5.8 8.9 12.2 13.8 14.7 10.9 16.9 12.6 28.5 13.4 12.9 20.8 20.8 13.6 20.8 12.9 19.2 15.5 9.4 11.7 26.0 29.4 29.4 17.6 20.3 9.1 18.6 25.9 8.6 36.1 9.8 19.4 20.4 16.6 17.0 13.9 26.5 12.6 11.8 16.8 25.2 19.5 13.4 15.0 26.7 21.0 16.3 21.9 21.4 39.8 19.1 13.7 19.2 19.2 10.2 26.2 32.4 19.5 25.8 16.1 9.6 21.2 12.7 18.4 28.8 15.6 35.2 21.7 18.1 20.7 15.9 22.8 14.1 19.6 6.6 6.5 7.1 10.5 6.4 9.4 6.3 6.9 10.1 7.3 5.2 8.6 7.4 3.3 11.3 6.6 6.6 8.9 7.8 16.0 16.0 15.4 17.8 16.9 13.6 16.9 15.3 15.5 15.0 15.4 14.7 7.1 0.0 5.5 11.8 8.9 22.0 4.5 9.4 19.4 6.5 11.1 9.0 10.9 10.0 3.5 9.2 6.2 12.9 12.4 14.6 21.5 15.0 1.9 10.0 7.2 9.4 7.2 21.9 9.7 10.7 9.8 8.0 14.8 14.9 2.5 6.9 8.6 3.4 8.6 10.1 6.5 7.3 6.1 5.9 8.2 3.0 8.7 6.9 3.6 7.5 6.1 7.6 4.1 7.1 7.6 13.0 9.1 7.9 9.5 8.5 8.3 6.7 3.4 6.5 13.1 6.2 7.7 8.0 10.2 12.0 20.2 14.2 11.1 6.4 7.5 5.9 ASPHD1 ENSG00000174939 "Aspartate beta-hydroxylase domain containing 1" Q5U4P2 16 29900375-29919864 "Predicted intracellular proteins, Predicted membrane proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 138.6;choroid plexus: 79.3;pituitary gland: 36.4" "Cell type enhanced" "Detected in many" "Cholangiocytes: 27.1;Enteroendocrine cells: 29.4;Excitatory neurons: 25.1;Gastric mucus-secreting cells: 32.1;Inhibitory neurons: 22.6;Oligodendrocytes: 29.3;Pancreatic endocrine cells: 29.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 61.7;Hep G2: 79.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045175 Uncertain NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 1: Pancreatic cells - Digestion" "HPA045175: AB_10959899" "unprognostic (1.58e-1)" "unprognostic (5.50e-2)" "unprognostic (4.74e-3)" "unprognostic (2.20e-3)" "unprognostic (1.34e-3)" "unprognostic (6.96e-2)" "unprognostic (5.75e-2)" "unprognostic (1.18e-1)" "unprognostic (2.57e-2)" "unprognostic (8.37e-2)" "prognostic favorable (7.38e-4)" "unprognostic (5.55e-2)" "unprognostic (6.17e-2)" "unprognostic (1.97e-2)" "unprognostic (1.90e-1)" "unprognostic (2.97e-1)" "unprognostic (9.03e-2)" 5.5 5.1 113.3 0.7 119.8 0.1 0.8 106.3 138.6 1.3 79.3 1.3 2.5 3.0 0.1 0.4 1.3 14.8 0.8 108.6 101.7 4.4 0.7 1.1 0.2 113.3 113.9 1.3 9.1 0.8 36.4 0.2 111.9 1.5 0.9 2.3 4.9 0.5 0.2 0.3 1.7 1.4 110.4 0.3 20.9 5.9 110.1 0.0 0.1 0.2 0.2 0.8 0.4 117.6 3.3 14.5 0.0 16.7 0.0 2.4 0.9 15.8 5.1 18.0 12.9 35.1 61.7 6.2 39.4 10.5 13.0 2.4 2.0 4.2 3.4 1.0 2.4 3.1 50.9 79.1 29.1 0.7 40.5 18.3 3.9 26.7 2.7 19.4 0.7 11.3 0.2 13.1 4.3 32.1 0.9 0.6 23.0 13.7 13.8 1.2 0.0 2.5 18.4 0.4 47.3 19.3 0.2 26.1 5.2 0.3 10.0 11.9 1.2 7.5 13.2 0.4 4.5 1.1 0.4 0.6 23.7 41.4 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 113.3 119.8 106.3 138.6 108.6 101.7 113.3 113.9 111.9 110.4 110.1 117.6 0.7 0.0 5.1 4.9 0.1 0.6 4.8 2.5 0.0 19.2 4.3 3.9 0.3 27.1 0.5 1.8 4.2 0.0 0.0 2.6 1.9 17.3 1.9 0.7 9.4 0.9 29.4 0.0 25.1 20.2 0.4 7.8 32.1 1.4 1.3 0.5 0.0 0.2 4.0 6.7 22.6 4.2 6.1 0.0 0.3 1.2 0.3 0.9 1.8 5.6 0.0 1.7 0.0 9.0 29.3 29.3 0.3 0.7 0.1 8.1 1.7 3.7 0.3 10.2 0.0 0.2 2.5 1.2 1.0 0.0 0.6 0.3 0.2 4.8 4.2 2.8 ASPM "ASP, Calmbp1, FLJ10517, FLJ10549, MCPH5" ENSG00000066279 "Assembly factor for spindle microtubules" Q8IZT6 1 197084121-197146694 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Calmodulin-binding "Cancer-related genes, Disease variant, Mental retardation, Primary microcephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 10.1;lymphoid tissue: 17.0" "Cell type enhanced" "Detected in many" "Erythroid cells: 99.5;Granulosa cells: 121.1;Plasma cells: 44.8;Spermatocytes: 43.8;Spermatogonia: 44.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" CAB017816 Approved "Plasma membrane,Cytosol" NA Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Cytosol" "CAB017816: " "unprognostic (3.24e-1)" "unprognostic (1.56e-1)" "unprognostic (2.81e-2)" "prognostic unfavorable (1.97e-4)" "unprognostic (3.67e-1)" "unprognostic (3.47e-2)" "prognostic unfavorable (1.25e-4)" "prognostic unfavorable (2.41e-4)" "unprognostic (4.67e-3)" "unprognostic (9.29e-2)" "prognostic unfavorable (2.40e-4)" "unprognostic (1.03e-1)" "unprognostic (0.00e+0)" "unprognostic (7.31e-3)" "unprognostic (1.23e-1)" "unprognostic (4.94e-2)" "unprognostic (3.66e-2)" 0.2 0.1 0.0 3.0 0.0 10.1 0.4 0.0 0.1 0.2 0.0 1.6 2.1 0.3 0.0 1.5 0.0 0.3 0.1 0.0 0.0 0.0 0.6 0.3 5.3 0.0 0.0 0.1 0.0 0.0 0.0 1.5 0.0 0.1 1.9 0.0 0.2 0.0 0.0 2.7 1.9 0.7 0.0 0.9 1.1 3.2 0.1 17.0 0.1 0.0 5.1 0.6 0.4 0.2 44.6 22.9 39.1 23.2 1.9 5.5 14.7 35.1 23.2 32.6 25.6 16.7 31.1 45.4 12.5 27.5 13.8 40.2 33.6 12.1 39.1 41.8 25.4 33.1 56.1 12.8 0.4 51.9 20.5 0.6 1.0 26.1 15.2 7.3 31.5 32.9 41.8 50.7 29.0 16.0 40.6 10.3 17.8 24.8 6.4 30.2 55.5 31.7 7.4 11.4 20.4 29.5 50.6 20.6 9.5 20.8 26.9 12.7 28.9 20.9 20.0 34.9 61.2 13.9 21.6 26.8 14.9 11.0 42.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.6 0.0 1.1 1.3 5.8 6.1 1.5 4.0 2.2 0.1 2.4 2.4 1.1 0.0 1.3 1.8 0.0 20.0 7.8 7.7 0.0 0.3 3.9 2.9 6.2 4.3 0.0 99.5 2.0 0.0 14.8 9.8 13.3 8.1 1.3 121.1 6.4 2.2 11.6 0.0 4.8 6.8 4.1 6.4 2.4 4.5 0.6 6.4 0.0 0.0 0.9 0.7 4.1 0.0 1.0 0.5 0.2 1.5 44.8 2.0 0.4 0.4 0.8 0.3 0.0 0.6 7.0 43.8 44.7 27.1 3.4 3.7 9.1 5.7 16.9 2.1 ASRGL1 "ALP, ALP1, FLJ22316" ENSG00000162174 "Asparaginase and isoaspartyl peptidase 1" Q7L266 11 62337448-62393412 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 112.7;cervix: 121.7;testis: 100.5" "Cell type enhanced" "Detected in many" "Early spermatids: 372.5;Endometrial ciliated cells: 414.6;Glandular and luminal cells: 437.1;Late spermatids: 597.6;Proximal tubular cells: 214.1;Spermatocytes: 534.3" "Cancer enhanced" "Detected in all" "endometrial cancer: 53.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 277.9;eosinophil: 269.5" "Lineage enriched" "Detected in all" 4 "granulocytes: 277.9" "Cell line enhanced" "Detected in many" "EFO-21: 85.2;HAP1: 83.9;SCLC-21H: 112.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029725, HPA055572, CAB070192" Enhanced Approved "Nucleoplasm,Microtubules,Cytokinetic bridge" Yes NA "Cluster 2: Granulocytes - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 44: Endometrium - Transcription" Microtubules "Nucleoplasm, Cytokinetic bridge" "CAB070192: AB_2665720, HPA029725: AB_10602328, HPA055572: AB_2682854" "unprognostic (1.14e-1)" "unprognostic (8.38e-3)" "prognostic favorable (6.14e-4)" "prognostic favorable (1.56e-5)" "unprognostic (5.35e-2)" "unprognostic (8.19e-2)" "prognostic unfavorable (9.46e-4)" "unprognostic (8.67e-2)" "unprognostic (1.85e-1)" "unprognostic (3.54e-2)" "unprognostic (2.71e-1)" "unprognostic (4.44e-1)" "prognostic favorable (4.32e-7)" "unprognostic (2.28e-2)" "unprognostic (1.53e-1)" "unprognostic (5.43e-3)" "unprognostic (1.40e-1)" 13.8 3.7 94.2 6.5 95.4 14.4 12.0 92.5 103.5 121.7 71.7 14.2 6.8 26.4 3.1 2.1 68.1 11.2 6.2 87.1 93.3 42.5 10.2 25.8 5.6 87.5 102.7 1.8 13.4 2.3 21.2 3.2 87.6 23.8 17.1 17.8 13.2 7.2 7.3 2.9 9.5 4.4 83.4 4.7 15.1 100.5 112.7 10.3 6.7 3.0 4.7 4.3 2.0 90.0 2.4 19.5 20.9 27.2 0.1 0.0 16.4 2.3 0.8 3.6 3.5 32.0 8.5 1.9 85.2 0.3 9.3 1.8 83.9 0.7 4.2 2.6 34.4 1.2 28.1 23.5 0.6 24.0 30.8 0.8 0.2 1.6 0.4 1.3 39.4 47.8 24.5 21.5 0.9 37.5 65.3 15.9 28.5 13.6 15.2 26.1 12.5 11.8 73.3 5.9 112.3 16.1 16.4 28.2 14.4 21.2 15.0 12.1 2.0 0.4 15.4 1.2 9.5 32.8 33.6 3.0 0.8 12.3 9.7 277.9 68.6 269.5 2.8 50.8 1.9 2.4 1.0 3.3 39.7 1.5 2.3 3.4 16.3 11.5 38.5 7.2 0.8 24.2 94.2 95.4 92.5 103.5 87.1 93.3 87.5 102.7 87.6 83.4 112.7 90.0 29.2 6.4 27.8 56.8 5.2 3.4 2.5 2.2 0.6 24.4 13.8 6.6 2.4 42.9 4.1 22.0 33.3 2.3 3.2 14.0 133.1 30.3 372.5 414.6 39.9 31.2 47.2 14.1 13.9 22.3 2.4 4.0 19.9 437.1 80.9 16.6 49.2 3.7 25.0 16.8 18.6 67.4 6.1 11.4 6.4 597.6 8.7 26.9 1.8 9.4 10.5 80.8 4.1 15.1 22.0 7.8 7.5 7.2 13.9 35.4 2.9 214.1 5.4 37.1 13.1 7.7 6.1 534.3 48.6 0.1 1.3 0.8 7.8 10.8 36.0 15.9 ASTN2 KIAA0634 ENSG00000148219 "Astrotactin 2" O75129 9 116423112-117415070 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 39.2" "Cell type enhanced" "Detected in many" "Astrocytes: 354.6;Excitatory neurons: 370.0;Inhibitory neurons: 1011.0;Late spermatids: 228.2;Oligodendrocyte precursor cells: 900.3;Oligodendrocytes: 225.9" "Cancer enhanced" "Detected in all" "prostate cancer: 15.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SH-SY5Y: 37.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027035 Uncertain Approved Nucleoplasm,Cytosol No No "Cluster 15: NK-cells - Transcription" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol Nucleoplasm "HPA027035: AB_1845122" "unprognostic (3.25e-2)" "unprognostic (2.70e-2)" "unprognostic (7.41e-3)" "unprognostic (5.42e-3)" "unprognostic (1.89e-1)" "unprognostic (2.67e-2)" "unprognostic (1.55e-1)" "unprognostic (1.02e-2)" "unprognostic (2.94e-1)" "unprognostic (2.80e-1)" "unprognostic (3.40e-2)" "unprognostic (2.93e-1)" "prognostic favorable (6.66e-16)" "unprognostic (3.28e-1)" "unprognostic (2.01e-1)" "unprognostic (1.63e-1)" "unprognostic (1.57e-1)" 3.3 9.8 26.1 2.7 26.3 3.6 4.3 39.0 36.0 5.3 9.0 5.2 3.4 3.2 3.9 2.2 8.0 2.5 22.5 27.0 25.8 5.5 4.1 2.2 2.4 29.3 36.2 2.8 6.7 3.1 11.6 1.8 28.7 25.2 3.2 13.4 5.8 11.3 7.3 2.4 4.1 2.8 21.4 2.4 5.6 17.6 35.0 6.0 1.8 5.6 1.8 3.2 3.5 39.2 3.7 12.0 4.3 7.1 7.6 7.0 15.4 5.7 2.3 2.5 2.8 8.1 4.4 8.8 6.1 3.8 9.3 1.3 11.5 0.6 3.1 4.8 2.9 3.1 5.8 17.0 3.0 1.8 6.2 9.5 1.1 7.8 0.7 5.4 1.8 10.5 3.9 5.9 7.9 3.8 4.1 1.4 13.2 10.6 6.4 4.9 27.5 2.5 8.0 12.3 6.3 37.9 6.8 2.0 4.8 14.5 15.5 1.3 3.5 5.9 9.1 5.6 4.9 9.0 5.0 8.3 10.5 2.0 25.8 2.5 0.4 0.5 2.8 0.3 3.6 1.5 3.1 2.4 0.2 1.6 3.0 2.5 1.9 5.9 0.6 0.9 8.8 1.0 26.1 26.3 39.0 36.0 27.0 25.8 29.3 36.2 28.7 21.4 35.0 39.2 0.6 6.4 8.9 354.6 1.1 1.3 3.2 0.4 1.2 4.9 4.2 4.8 22.7 2.8 5.0 1.8 10.4 0.4 1.0 0.4 3.9 0.8 122.5 4.7 5.5 1.3 12.6 0.4 370.0 1.1 0.4 4.9 4.1 0.7 6.3 37.0 0.7 2.9 3.2 10.1 1011.0 1.0 0.0 0.0 1.6 228.2 2.8 1.0 0.0 36.5 0.2 3.0 0.0 900.3 225.9 0.5 2.1 5.7 3.6 11.7 5.7 6.9 11.7 5.1 0.0 1.9 2.0 7.7 13.2 0.3 0.6 0.3 3.8 1.9 1.8 2.2 ATAD2 "ANCCA, CT137, DKFZp667N1320, MGC29843, MGC5254, PRO2000" ENSG00000156802 "ATPase family AAA domain containing 2" Q6PL18 8 123319850-123416350 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 28.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 79.1;Spermatocytes: 106.0;Spermatogonia: 82.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 294.4" "Low region specificity" "Detected in all" "HPA029424, CAB056158" Enhanced Enhanced Nucleoplasm Yes Yes "Cluster 33: Neutrophils - Chromatin organization" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB056158: AB_2665580, HPA029424: AB_10611680" "unprognostic (1.56e-1)" "unprognostic (4.55e-2)" "unprognostic (2.07e-1)" "prognostic unfavorable (2.04e-4)" "unprognostic (2.08e-1)" "unprognostic (4.44e-2)" "unprognostic (2.98e-2)" "unprognostic (2.74e-3)" "unprognostic (2.02e-3)" "unprognostic (5.62e-2)" "unprognostic (1.19e-2)" "unprognostic (4.98e-2)" "prognostic unfavorable (8.33e-15)" "unprognostic (1.15e-2)" "unprognostic (1.82e-1)" "unprognostic (4.84e-2)" "unprognostic (6.17e-2)" 2.9 3.4 3.8 7.7 3.6 26.5 6.8 2.6 3.9 12.8 2.0 5.3 5.0 4.3 3.8 6.8 3.4 3.2 5.8 3.2 4.5 1.4 9.9 4.1 14.4 2.9 3.8 7.0 3.3 1.9 3.9 4.8 2.6 10.3 6.9 1.4 4.3 4.7 9.3 6.8 5.2 4.1 2.8 4.9 4.7 18.9 5.1 28.3 3.9 3.2 12.8 4.8 3.9 2.8 103.7 39.6 55.0 19.0 9.7 12.3 24.3 79.2 27.2 66.8 73.9 30.1 43.8 67.2 23.6 25.2 26.5 48.3 74.2 25.6 106.1 94.3 39.0 121.2 41.0 61.4 3.8 44.6 57.4 4.1 3.8 63.6 21.0 14.3 20.7 38.6 57.7 66.4 50.4 107.1 129.5 32.8 10.0 77.8 38.4 66.5 65.6 36.4 23.8 46.7 70.2 30.5 114.4 294.4 20.8 22.1 60.2 41.2 13.0 50.4 69.3 40.2 96.6 21.2 40.7 60.8 32.9 72.9 40.4 5.3 0.8 3.3 1.6 0.8 2.2 2.6 2.3 2.7 1.4 1.5 1.5 1.7 0.2 2.5 1.9 0.1 4.6 1.0 3.8 3.6 2.6 3.9 3.2 4.5 2.9 3.8 2.6 2.8 5.1 2.8 4.8 6.4 11.0 9.4 18.5 15.8 27.9 9.1 14.2 2.8 17.3 21.2 27.3 2.8 10.2 3.7 4.2 14.9 15.3 9.0 1.9 3.5 54.9 7.9 17.3 9.6 1.2 79.1 25.6 2.2 26.2 17.1 13.3 17.5 14.5 37.9 7.1 16.3 11.2 1.7 16.4 13.1 4.1 8.2 6.9 24.4 7.5 11.7 1.8 14.0 6.3 6.3 17.5 11.6 2.8 3.5 4.3 13.9 34.0 20.7 3.1 1.0 5.4 1.9 0.0 9.5 17.5 106.0 82.4 23.7 12.1 13.5 22.8 3.7 14.6 24.5 ATF2 "CRE-BP1, CREB2, HB16, TREB7" ENSG00000115966 "Activating transcription factor 2" P15336 2 175072250-175168382 "Predicted intracellular proteins, Transcription factors" "DNA damage, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 153.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003769, HPA022134" Supported Supported Enhanced Nucleoplasm NA NA "Cluster 44: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 34: Spermatids - Unknown function" Nucleoplasm "CAB003769: AB_562241, HPA022134: AB_1845138" "unprognostic (1.11e-1)" "unprognostic (2.01e-1)" "unprognostic (9.81e-2)" "unprognostic (1.93e-1)" "unprognostic (9.29e-3)" "unprognostic (2.56e-1)" "prognostic unfavorable (7.08e-5)" "unprognostic (2.28e-2)" "unprognostic (3.70e-2)" "unprognostic (6.47e-2)" "unprognostic (7.17e-2)" "unprognostic (4.02e-2)" "unprognostic (4.40e-3)" "unprognostic (1.15e-2)" "unprognostic (1.50e-1)" "unprognostic (7.21e-3)" "unprognostic (6.70e-2)" 16.8 20.2 15.6 15.2 17.6 16.4 19.5 23.3 25.7 25.7 4.1 15.1 13.0 21.8 21.6 14.3 18.9 17.8 12.1 19.3 15.5 22.5 27.8 15.4 19.7 16.2 14.9 26.0 18.9 24.0 13.9 20.4 17.2 18.3 15.7 21.8 17.9 17.7 12.5 10.0 13.6 18.1 12.3 17.6 14.3 21.0 13.3 30.2 32.3 23.1 21.1 18.8 13.0 19.8 14.1 12.1 35.1 23.4 30.6 32.3 16.1 22.3 38.1 26.6 38.1 26.6 25.4 21.1 23.9 26.6 31.2 13.3 26.9 13.5 41.2 26.6 15.6 29.3 19.8 58.3 34.4 27.8 29.7 24.4 29.8 34.4 40.5 35.0 37.0 19.4 24.4 31.6 30.1 10.5 45.2 34.4 32.7 23.6 27.2 38.3 16.1 32.5 39.1 11.8 29.3 23.9 27.9 8.6 33.0 28.2 19.3 30.4 23.5 30.8 16.1 16.9 13.6 30.3 48.9 26.9 24.2 26.0 21.2 35.5 16.9 20.1 20.1 15.1 24.3 16.6 17.0 20.9 21.9 14.1 19.6 21.5 10.8 19.8 19.1 12.1 24.4 18.0 15.6 17.6 23.3 25.7 19.3 15.5 16.2 14.9 17.2 12.3 13.3 19.8 43.4 16.0 13.2 47.7 33.5 33.0 15.4 15.6 52.9 22.7 34.0 24.4 22.5 20.0 15.5 23.9 10.4 14.1 37.4 16.5 13.7 12.1 115.4 19.5 30.5 33.8 16.3 20.8 86.6 7.0 13.0 32.2 18.3 28.4 29.8 27.1 17.2 27.0 18.9 40.4 71.3 14.4 18.3 23.3 30.2 153.0 32.6 23.6 30.2 54.4 20.4 32.3 24.7 75.9 84.9 11.9 9.1 28.6 38.8 15.6 11.5 21.6 19.3 27.3 13.1 31.5 33.9 36.3 17.6 30.4 25.3 6.3 32.9 23.7 16.1 13.6 ATF7IP2 FLJ12668 ENSG00000166669 "Activating transcription factor 7 interacting protein 2" Q5U623 16 10326434-10483638 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 19.2" "Cell type enhanced" "Detected in all" "Spermatocytes: 145.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "K-562: 14.2;THP-1: 13.9" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "cerebral cortex: 3.3;hippocampal formation: 2.3" "HPA041156, HPA041228" Enhanced NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 1: K-562 - Erythropoiesis" "Cluster 52: Non-specific - Transcription" "HPA041156: AB_10795536, HPA041228: AB_10795586" "prognostic favorable (4.98e-4)" "unprognostic (3.87e-2)" "unprognostic (1.35e-2)" "unprognostic (6.31e-2)" "unprognostic (7.56e-2)" "unprognostic (2.87e-1)" "prognostic favorable (5.68e-5)" "unprognostic (2.47e-2)" "unprognostic (8.85e-2)" "unprognostic (2.32e-2)" "unprognostic (2.71e-1)" "unprognostic (1.90e-1)" "unprognostic (1.10e-3)" "unprognostic (2.43e-1)" "unprognostic (2.99e-1)" "unprognostic (2.41e-2)" "prognostic favorable (8.57e-5)" 1.8 6.7 2.4 4.2 1.7 5.7 1.5 0.7 3.6 3.0 0.9 1.9 3.0 1.4 3.6 1.5 4.8 1.3 5.2 3.0 1.8 2.4 9.2 2.1 8.8 1.0 0.9 2.2 5.6 0.6 1.2 3.2 1.2 1.4 2.0 4.7 0.8 1.7 1.6 2.9 2.0 2.2 1.0 5.1 6.2 19.2 1.6 10.7 3.7 1.3 8.6 5.1 1.1 2.7 0.7 1.6 1.3 4.3 3.3 3.8 6.9 1.7 0.3 0.4 0.0 0.5 7.2 0.0 3.5 0.0 1.4 1.0 6.3 1.5 0.4 6.2 4.3 8.4 1.3 6.0 1.6 7.8 3.5 4.2 1.4 0.1 0.0 1.7 2.9 13.1 14.2 0.0 4.0 1.3 9.9 6.1 7.0 9.6 1.5 13.0 0.0 4.3 1.4 3.3 0.0 0.8 6.8 1.3 0.7 4.3 2.4 13.9 1.6 0.0 1.9 0.1 0.0 2.8 7.3 1.2 0.0 4.8 1.9 0.1 0.5 0.0 4.5 1.0 11.6 2.4 4.6 4.4 1.6 3.6 3.8 4.3 0.1 3.5 1.0 2.5 7.2 2.0 2.4 1.7 0.7 3.6 3.0 1.8 1.0 0.9 1.2 1.0 1.6 2.7 28.5 12.8 16.2 26.1 62.1 11.5 11.6 37.3 19.9 18.5 11.0 8.4 53.9 7.2 22.8 12.9 100.1 60.1 38.9 15.4 99.7 16.8 30.7 24.2 8.2 17.6 23.2 30.9 71.4 10.9 60.5 12.8 81.1 14.9 1.3 19.9 13.2 115.2 23.6 5.0 45.5 14.6 24.4 23.6 23.5 31.6 7.5 33.5 16.0 82.4 13.8 38.2 24.7 39.7 8.4 6.7 20.7 6.8 37.1 6.1 10.0 39.0 88.7 35.4 13.1 6.0 13.2 145.8 89.2 19.6 19.5 27.1 46.0 17.3 16.8 21.7 ATG10 "APG10L, DKFZP586I0418, FLJ13954" ENSG00000152348 "Autophagy related 10" Q9H0Y0 5 81972023-82276857 "Predicted intracellular proteins" "Autophagy, Protein transport, Transport, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 96.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044163 Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoli Nucleoplasm "HPA044163: AB_2678842" "unprognostic (1.20e-1)" "unprognostic (7.96e-2)" "unprognostic (1.07e-2)" "unprognostic (2.51e-2)" "unprognostic (3.18e-2)" "unprognostic (1.85e-1)" "prognostic unfavorable (3.22e-5)" "unprognostic (5.60e-3)" "unprognostic (2.96e-2)" "unprognostic (1.92e-2)" "unprognostic (2.48e-1)" "unprognostic (1.21e-1)" "unprognostic (9.62e-2)" "unprognostic (1.67e-1)" "unprognostic (2.10e-1)" "unprognostic (1.30e-3)" "unprognostic (4.43e-1)" 4.0 5.4 4.8 4.1 4.9 5.6 7.0 8.3 5.7 3.5 7.9 5.5 3.3 4.6 7.8 4.9 4.2 4.3 4.6 5.0 4.7 5.7 6.5 3.7 3.5 5.0 4.5 3.2 4.4 11.6 4.0 4.7 5.0 5.6 6.1 3.5 3.7 5.6 7.2 6.6 3.3 5.5 4.6 4.1 4.4 10.4 5.0 7.8 7.1 3.1 4.3 4.0 3.9 8.0 4.7 12.6 7.9 23.0 5.3 10.0 20.1 5.4 4.4 3.9 6.0 3.7 16.7 8.4 4.4 8.8 29.7 2.5 5.9 12.2 5.1 14.4 4.2 9.2 11.4 4.0 5.0 4.8 7.3 9.3 8.2 5.7 4.7 6.0 7.4 17.7 11.3 6.8 14.4 9.5 11.0 5.2 11.0 3.5 8.2 8.0 11.5 20.1 10.0 6.7 11.8 16.9 8.8 4.9 10.0 13.6 9.4 8.9 6.0 7.0 6.6 3.8 11.5 9.4 17.0 11.5 9.8 11.4 11.7 2.7 5.7 8.5 5.1 5.8 4.8 3.6 4.5 4.8 7.5 4.5 4.2 5.2 7.4 6.5 4.3 5.6 5.0 4.1 4.8 4.9 8.3 5.7 5.0 4.7 5.0 4.5 5.0 4.6 5.0 8.0 8.1 16.0 15.6 69.2 9.3 24.9 17.4 16.3 14.2 16.3 15.6 14.4 9.3 12.8 16.7 12.9 10.4 25.5 9.7 8.2 15.6 15.7 67.6 7.7 11.4 13.0 9.6 14.5 56.4 18.4 46.3 15.1 6.6 9.7 11.4 22.1 10.0 12.8 18.3 18.5 52.2 7.8 4.1 14.1 28.4 96.6 6.8 12.3 32.0 57.1 17.2 12.5 15.5 67.8 76.5 15.2 9.9 10.1 10.1 12.0 8.5 18.8 8.8 15.2 0.0 18.2 13.6 54.1 22.9 13.8 32.0 21.1 14.3 15.6 11.5 14.0 ATG13 KIAA0652 ENSG00000175224 "Autophagy related 13" O75143 11 46617527-46674818 "Cancer-related genes, Predicted intracellular proteins, Transporters" Autophagy "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039350 Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" Cytosol "Nucleoplasm, Plasma membrane" "HPA039350: AB_10673142" "unprognostic (3.66e-1)" "unprognostic (1.14e-1)" "unprognostic (1.51e-1)" "unprognostic (1.65e-1)" "unprognostic (5.36e-2)" "unprognostic (2.31e-1)" "prognostic unfavorable (8.59e-5)" "unprognostic (1.05e-1)" "unprognostic (1.10e-1)" "unprognostic (1.27e-1)" "unprognostic (1.35e-1)" "unprognostic (7.57e-2)" "unprognostic (2.44e-2)" "unprognostic (2.41e-1)" "unprognostic (2.14e-1)" "unprognostic (7.68e-2)" "unprognostic (3.47e-1)" 32.3 39.7 55.9 26.1 67.6 60.5 30.1 49.4 63.7 30.6 46.1 26.5 29.3 28.2 32.2 32.0 32.1 29.6 36.8 55.2 51.8 28.7 43.9 25.3 31.5 60.2 59.4 29.7 44.6 37.5 57.7 21.9 61.8 31.1 24.1 48.4 35.9 25.5 34.5 39.6 28.0 24.8 51.8 36.4 36.4 82.0 59.6 40.6 36.8 33.4 33.6 27.4 29.1 87.9 32.8 58.5 44.1 26.1 60.2 70.0 44.5 37.5 65.4 45.0 57.0 40.2 31.7 30.2 25.6 56.5 58.1 38.8 42.7 50.3 45.2 57.9 81.1 32.8 39.7 71.2 67.4 44.1 54.1 84.9 59.0 31.0 67.9 63.9 45.0 69.4 57.8 66.8 40.8 48.8 44.0 65.1 55.0 59.5 49.9 41.4 57.0 53.7 29.9 34.5 41.6 42.1 51.2 40.6 55.4 42.1 58.0 89.5 44.6 54.7 33.3 51.1 41.2 61.1 73.8 38.6 67.8 39.3 40.9 41.7 36.1 48.5 35.1 42.6 27.9 27.1 31.2 27.8 35.0 21.7 26.4 29.2 67.7 31.5 35.1 25.6 44.7 39.9 55.9 67.6 49.4 63.7 55.2 51.8 60.2 59.4 61.8 51.8 59.6 87.9 10.6 16.0 16.2 14.7 16.9 9.3 12.0 9.0 13.1 22.7 16.7 12.3 13.2 8.6 12.0 12.9 39.6 9.9 25.4 24.5 7.9 18.9 42.7 30.0 17.3 12.7 18.0 28.2 23.4 32.3 22.4 14.8 20.9 46.1 8.8 22.5 13.2 22.5 15.1 33.7 25.7 22.6 14.2 19.1 9.8 46.8 11.5 15.7 12.4 15.0 22.8 16.3 19.6 25.1 61.0 30.4 12.9 11.3 36.6 19.9 19.5 13.5 9.4 32.2 13.1 16.9 19.9 46.3 16.3 15.8 11.5 26.4 18.0 9.8 11.9 24.3 ATG16L1 "APG16L, ATG16A, ATG16L, FLJ10035, WDR30" ENSG00000085978 "Autophagy related 16 like 1" Q676U5 2 233210051-233295674 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Autophagy, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012577, HPA063900" Supported Approved Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 5: NTERA-2 - Transcription" "Cluster 44: Endometrium - Transcription" Cytosol "HPA012577: AB_1845155, HPA063900: AB_2685146" "unprognostic (1.24e-1)" "unprognostic (1.07e-1)" "unprognostic (3.57e-2)" "unprognostic (2.22e-3)" "unprognostic (1.89e-1)" "unprognostic (4.49e-1)" "prognostic unfavorable (1.48e-5)" "unprognostic (2.51e-1)" "unprognostic (1.80e-1)" "unprognostic (1.85e-2)" "unprognostic (6.66e-3)" "unprognostic (1.16e-2)" "prognostic unfavorable (1.70e-4)" "unprognostic (3.93e-2)" "unprognostic (1.41e-1)" "unprognostic (2.41e-1)" "unprognostic (2.08e-1)" 7.6 7.8 7.0 3.8 7.5 14.3 8.8 7.9 8.4 8.1 12.8 11.1 5.0 9.6 5.5 11.6 7.1 3.3 10.7 7.3 6.6 9.2 15.1 7.6 5.8 6.5 6.3 8.5 8.6 5.3 5.5 4.0 6.9 12.1 5.2 5.6 11.5 4.3 19.9 17.2 11.1 5.2 6.3 11.5 11.1 13.5 6.5 5.9 11.2 6.1 5.2 11.5 8.2 7.7 13.3 12.2 4.9 8.5 12.4 8.0 14.0 11.4 9.3 9.6 8.9 8.9 9.7 3.1 3.7 8.9 14.3 7.7 9.8 6.4 9.8 6.2 7.7 7.1 9.1 14.6 9.1 5.6 9.0 5.3 9.1 11.5 8.7 7.2 9.0 4.7 7.6 2.9 10.2 9.3 6.7 11.2 19.1 14.1 17.6 4.8 10.3 2.6 9.9 8.4 8.8 6.5 7.8 8.5 8.5 7.4 5.3 7.1 10.7 6.2 5.4 9.6 10.3 6.5 3.9 6.1 10.5 5.7 10.2 0.0 1.7 2.9 4.8 1.4 3.7 2.0 3.1 4.4 1.4 2.2 3.5 3.5 1.2 4.1 4.7 0.7 3.8 2.1 7.0 7.5 7.9 8.4 7.3 6.6 6.5 6.3 6.9 6.3 6.5 7.7 6.1 6.4 8.2 5.2 7.4 9.1 4.6 5.2 3.4 8.4 12.0 6.6 5.6 7.2 11.6 5.5 4.2 4.6 20.9 13.9 5.9 8.3 1.2 16.4 10.9 6.4 9.0 3.8 31.0 6.7 6.2 5.2 8.2 31.8 9.5 6.4 6.1 10.2 5.6 1.7 25.6 5.1 6.1 6.3 5.7 1.7 4.1 5.1 10.6 8.4 6.6 7.1 4.1 11.6 21.4 16.8 8.0 3.8 8.1 7.1 9.2 5.6 11.5 19.5 6.6 5.8 6.9 11.0 17.6 7.3 13.2 3.7 19.2 5.1 8.4 6.0 ATL1 "AD-FSP, FSP1, SPG3, SPG3A" ENSG00000198513 "Atlastin GTPase 1" Q8WXF7 14 50532509-50634017 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Hydrolase "Disease variant, Hereditary spastic paraplegia, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 42.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 138.6;Inhibitory neurons: 95.5;Oligodendrocyte precursor cells: 81.4;Oligodendrocytes: 136.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 22.9" "Lineage enriched" "Detected in many" 5 "granulocytes: 22.9" "Cell line enhanced" "Detected in many" "HDLM-2: 19.8;SCLC-21H: 17.1;SH-SY5Y: 15.4;SiHa: 18.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027550 Enhanced NA NA "Cluster 38: Basophils - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 44: HDLM-2 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA027550: AB_10600983" "unprognostic (2.06e-2)" "unprognostic (7.57e-3)" "unprognostic (1.82e-1)" "unprognostic (7.93e-2)" "unprognostic (2.44e-1)" "unprognostic (1.38e-1)" "unprognostic (2.29e-1)" "unprognostic (1.88e-1)" "unprognostic (7.31e-2)" "unprognostic (1.52e-1)" "unprognostic (1.09e-1)" "unprognostic (6.50e-2)" "unprognostic (1.22e-2)" "unprognostic (3.59e-2)" "unprognostic (2.39e-1)" "unprognostic (4.95e-2)" "unprognostic (1.23e-2)" 4.1 5.6 29.1 3.3 33.2 0.2 11.3 18.8 42.8 5.7 2.2 8.1 3.9 9.0 2.9 5.3 6.5 4.8 2.1 37.1 30.3 4.0 0.3 4.3 1.7 25.2 21.5 10.5 3.7 1.9 7.7 0.5 29.6 8.3 5.6 9.5 13.2 8.6 1.1 9.6 4.9 15.6 24.9 1.1 4.6 8.7 25.0 1.1 2.5 2.2 1.8 6.7 5.3 30.0 1.2 1.1 4.8 4.6 0.3 0.0 3.4 5.7 9.6 6.2 7.4 0.0 4.1 3.7 2.5 0.1 4.5 1.4 8.4 1.1 2.4 19.8 1.8 1.2 0.8 0.3 0.2 0.2 3.1 3.6 1.9 8.6 1.6 0.3 0.4 4.2 0.1 0.5 8.7 0.4 1.2 0.6 4.4 1.4 1.5 0.6 12.1 0.4 1.7 2.5 17.1 15.4 18.9 1.1 0.6 0.0 0.0 2.1 1.3 6.0 4.6 0.0 2.9 0.9 4.7 1.7 3.9 0.2 0.2 22.9 0.1 4.9 2.5 0.0 0.5 3.8 0.9 2.1 1.2 1.1 2.1 4.2 0.3 0.6 0.5 2.8 0.4 2.0 29.1 33.2 18.8 42.8 37.1 30.3 25.2 21.5 29.6 24.9 25.0 30.0 3.0 6.4 2.6 31.6 3.7 5.1 6.2 10.3 6.2 27.8 18.1 16.3 1.9 5.7 6.6 5.5 0.0 0.4 6.7 9.3 0.0 10.6 31.4 4.2 5.4 4.8 7.2 0.4 138.6 13.1 1.1 14.6 5.6 2.3 6.3 1.2 5.0 0.0 1.6 11.8 95.5 1.9 2.0 0.0 3.6 5.7 13.4 5.5 8.8 20.6 1.3 23.0 2.1 81.4 136.7 7.2 6.0 17.0 5.2 3.9 13.2 3.4 14.2 8.6 19.7 4.5 10.8 31.9 5.7 4.1 5.5 0.1 3.8 0.2 3.6 3.3 ATP11A "ATPIH, ATPIS, KIAA1021" ENSG00000068650 "ATPase phospholipid transporting 11A" P98196 13 112690329-112887168 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 218.0;Alveolar cells type 2: 215.0;Cone photoreceptor cells: 235.6;Glandular and luminal cells: 176.3;Oligodendrocytes: 138.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035583, HPA035584" Approved Supported "Golgi apparatus,Vesicles" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" Vesicles "Golgi apparatus" "HPA035583: AB_10671106, HPA035584: AB_10672096" "unprognostic (1.67e-1)" "unprognostic (5.06e-3)" "unprognostic (1.58e-1)" "unprognostic (5.27e-2)" "unprognostic (6.58e-2)" "unprognostic (8.84e-2)" "unprognostic (5.87e-3)" "unprognostic (1.80e-2)" "unprognostic (6.97e-2)" "unprognostic (1.54e-3)" "unprognostic (3.93e-2)" "unprognostic (4.23e-1)" "prognostic favorable (7.44e-4)" "unprognostic (3.85e-2)" "unprognostic (3.69e-1)" "unprognostic (3.26e-2)" "unprognostic (7.40e-3)" 10.2 10.4 12.3 8.9 22.0 18.2 6.1 18.3 16.8 13.0 5.7 4.4 9.9 10.1 5.8 7.0 8.7 15.0 21.4 9.7 12.5 12.7 10.1 39.5 5.8 25.3 22.2 6.5 12.4 23.1 16.2 10.1 22.9 4.3 3.2 14.9 9.0 3.9 13.1 8.9 8.3 9.1 15.7 8.9 5.3 8.9 21.9 8.2 13.9 17.3 6.1 6.5 5.9 40.2 28.0 14.0 17.5 20.5 8.7 11.7 30.9 13.0 7.6 10.9 8.8 44.5 31.5 14.1 15.5 11.0 14.0 23.2 15.8 10.8 10.5 14.2 14.9 16.3 11.9 23.3 13.6 30.8 25.5 7.9 8.2 13.2 8.0 8.8 29.0 12.6 11.4 2.3 7.7 10.5 14.1 19.4 7.5 31.8 9.9 12.2 7.1 8.1 59.3 6.4 27.8 7.7 12.7 16.3 10.7 22.4 6.2 40.4 19.2 0.0 23.3 14.1 9.9 7.4 15.5 5.9 4.8 28.3 12.2 0.0 1.1 1.7 0.4 1.6 0.3 0.6 0.2 0.2 0.6 1.8 0.3 0.2 3.1 0.0 1.5 0.5 0.0 0.3 12.3 22.0 18.3 16.8 9.7 12.5 25.3 22.2 22.9 15.7 21.9 40.2 25.6 218.0 215.0 22.2 11.3 10.8 3.4 4.9 1.2 42.0 5.2 3.7 42.3 31.5 29.4 16.5 235.6 1.7 7.0 2.4 5.9 32.7 0.9 51.2 24.2 34.2 12.0 3.8 35.0 11.4 32.2 16.5 8.6 176.3 12.0 62.2 27.1 16.5 20.7 13.5 32.5 3.5 14.2 33.6 16.9 1.9 11.1 29.3 10.6 48.7 36.9 11.0 6.2 33.7 138.3 24.3 6.1 4.9 7.7 7.7 10.5 15.7 13.3 44.8 0.0 9.5 12.8 4.0 10.1 6.3 9.7 8.6 8.4 8.7 5.9 3.9 ATP6V1B2 "ATP6B2, HO57, VATB, Vma2, VPP3" ENSG00000147416 "ATPase H+ transporting V1 subunit B2" P21281 8 20197381-20226819 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" Hydrolase "Deafness, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 256.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1130.7" "Group enriched" "Detected in all" 10 "dendritic cells: 336.8;granulocytes: 1130.7;monocytes: 682.0" "Cell line enhanced" "Detected in all" "SK-MEL-30: 317.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008147 Enhanced Supported Vesicles NA NA 310000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 58: Brain - Synaptic function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA008147: AB_1845195" "unprognostic (1.90e-1)" "unprognostic (7.24e-3)" "unprognostic (3.62e-2)" "unprognostic (2.57e-1)" "unprognostic (2.84e-2)" "unprognostic (5.59e-3)" "unprognostic (1.76e-2)" "unprognostic (3.78e-2)" "unprognostic (4.68e-2)" "unprognostic (4.23e-3)" "unprognostic (1.29e-2)" "unprognostic (1.34e-1)" "prognostic favorable (8.41e-4)" "unprognostic (2.41e-1)" "unprognostic (2.09e-2)" "unprognostic (2.47e-2)" "unprognostic (5.25e-2)" 46.4 76.4 112.6 71.9 111.2 45.7 35.3 72.8 126.0 30.1 72.5 38.0 43.9 29.4 31.0 51.3 32.8 39.0 38.2 124.0 135.5 145.8 49.2 72.7 54.1 103.4 120.0 27.5 34.5 71.4 74.5 50.5 138.2 28.1 43.0 205.7 40.4 27.0 66.7 62.5 57.8 40.1 74.8 66.1 32.8 67.8 100.3 50.2 33.4 64.7 48.9 44.5 36.1 99.5 44.2 71.5 87.4 29.2 117.7 72.3 79.1 96.6 61.5 121.5 125.2 81.7 25.4 77.7 38.4 93.1 123.7 36.8 70.1 64.6 129.0 32.9 47.2 54.2 29.9 63.6 137.6 39.0 108.0 65.0 57.9 76.0 69.3 134.1 77.2 101.2 82.0 72.8 132.5 25.0 114.6 46.2 65.6 64.6 31.5 46.6 113.4 40.8 112.9 68.2 68.0 97.9 46.9 62.7 317.9 72.4 81.6 70.7 82.8 61.1 46.3 101.9 78.5 29.4 42.7 90.9 84.6 91.6 158.4 183.7 682.0 485.9 52.9 618.6 57.7 50.2 54.1 56.8 336.8 44.5 54.4 53.7 1130.7 50.8 576.1 82.7 73.0 622.6 112.6 111.2 72.8 126.0 124.0 135.5 103.4 120.0 138.2 74.8 100.3 99.5 16.6 25.6 20.7 20.5 28.1 58.0 28.4 52.1 33.0 106.1 18.5 15.6 17.6 25.8 28.8 29.5 102.2 109.2 38.9 23.3 80.3 43.2 40.8 20.2 13.6 24.1 74.4 35.8 64.3 38.5 56.4 38.8 25.0 35.9 22.2 22.3 25.7 34.7 178.5 190.1 68.0 21.4 36.7 185.2 178.7 24.4 19.6 167.6 104.9 30.0 169.1 51.5 20.6 27.6 29.0 45.2 19.7 28.2 20.7 17.4 75.0 256.7 18.0 137.8 13.1 29.3 34.2 121.6 55.3 43.3 71.6 124.6 27.1 23.1 24.7 20.1 ATP6V1FNB ENSG00000272899 "ATP6V1F neighbor" A0A1B0GUX0 7 128866330-128872047 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.7;kidney: 25.1;skeletal muscle: 11.7" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 2.0;Glandular and luminal cells: 1.9" "Cancer enhanced" "Detected in many" "renal cancer: 5.2" "Region enhanced" "Detected in many" "cerebellum: 11.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 3.9;U-266/70: 3.3;U-266/84: 3.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 44: Endometrium - Transcription" "unprognostic (8.17e-2)" "unprognostic (3.00e-1)" "unprognostic (1.45e-2)" "prognostic unfavorable (8.21e-4)" "unprognostic (1.23e-1)" "unprognostic (9.98e-2)" "unprognostic (5.10e-2)" "unprognostic (1.18e-3)" "unprognostic (1.39e-1)" "unprognostic (1.19e-1)" "unprognostic (2.63e-2)" "unprognostic (2.20e-1)" "unprognostic (1.56e-2)" "unprognostic (1.50e-1)" "unprognostic (2.71e-1)" "unprognostic (1.87e-1)" "unprognostic (4.33e-3)" 2.1 0.4 3.2 0.4 2.6 0.3 0.6 11.7 3.7 1.3 0.0 1.1 1.2 0.5 0.2 1.5 1.1 0.8 6.8 2.8 0.7 25.1 0.1 0.5 0.2 0.8 1.0 0.3 0.3 0.4 1.0 0.3 1.1 0.9 0.1 0.7 0.6 0.1 11.7 0.7 4.1 0.4 0.2 0.7 1.7 3.7 1.2 0.2 0.6 0.2 0.2 0.8 0.8 1.8 0.6 0.3 0.3 3.0 0.9 0.4 0.0 0.2 0.4 0.4 0.2 0.2 3.9 1.0 0.2 0.1 0.7 0.7 0.3 0.1 0.2 3.0 0.5 1.2 0.2 0.0 0.5 0.1 2.9 0.4 0.2 0.2 0.2 0.5 0.1 0.3 0.8 1.6 0.3 0.2 0.3 1.5 0.0 0.1 0.2 0.5 1.0 0.5 0.1 0.2 1.2 0.6 0.2 1.5 0.2 0.8 0.3 0.5 0.1 1.5 0.3 2.6 0.2 3.3 3.8 0.7 1.5 1.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.2 2.6 11.7 3.7 2.8 0.7 0.8 1.0 1.1 0.2 1.2 1.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.7 2.0 0.2 0.0 0.0 0.0 0.2 0.1 0.1 0.0 1.9 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 ATP7B WND ENSG00000123191 "ATPase copper transporting beta" P35670 13 51930436-52012125 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Copper transport, Ion transport, Transport" Translocase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 22.9;Early spermatids: 30.2;Excitatory neurons: 24.5;Hepatocytes: 23.6;Inhibitory neurons: 25.4;Late spermatids: 74.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 32.8;CACO-2: 21.1;HEL: 53.0;RPTEC TERT1: 22.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA009137, HPA013187" Supported Supported "Golgi apparatus" NA NA "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 36: HEL - Hemostasis" "Cluster 9: Photoreceptor cells - Phototransduction" "Golgi apparatus" "HPA009137: AB_2668214, HPA013187: AB_1845206" "unprognostic (1.13e-2)" "unprognostic (1.61e-1)" "unprognostic (2.15e-1)" "prognostic unfavorable (5.01e-4)" "unprognostic (3.49e-1)" "unprognostic (5.51e-2)" "unprognostic (1.55e-2)" "unprognostic (1.18e-1)" "unprognostic (2.24e-1)" "unprognostic (5.77e-2)" "unprognostic (8.29e-2)" "unprognostic (1.17e-1)" "unprognostic (3.26e-3)" "unprognostic (4.66e-2)" "unprognostic (3.54e-1)" "unprognostic (6.21e-3)" "unprognostic (1.40e-1)" 3.6 0.9 1.3 0.6 1.2 2.2 1.7 2.0 2.1 1.8 0.8 2.9 10.6 1.5 0.1 0.7 2.0 7.0 2.1 2.5 1.4 2.2 8.6 1.4 0.3 0.8 1.2 1.9 2.0 6.4 1.2 7.1 1.1 2.0 2.7 3.7 3.0 0.9 1.1 1.0 6.0 1.7 0.5 0.4 4.4 8.4 1.7 0.7 1.2 1.8 0.2 1.6 1.2 0.7 0.8 2.8 5.2 4.5 1.0 0.8 32.8 1.5 0.5 1.6 1.2 21.1 0.1 0.1 0.6 2.7 3.6 0.3 4.0 4.4 1.0 0.4 7.5 53.0 0.5 14.7 1.4 0.6 11.8 1.9 4.7 0.2 2.0 2.1 3.7 3.7 14.4 0.2 1.5 1.0 0.2 0.9 1.7 6.6 1.8 2.0 1.4 0.0 22.5 3.4 3.3 2.2 1.9 2.8 1.8 5.5 8.0 0.5 2.0 0.3 1.7 2.8 0.6 0.6 0.7 0.2 0.1 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.2 2.0 2.1 2.5 1.4 0.8 1.2 1.1 0.5 1.7 0.7 5.4 6.4 0.0 10.7 0.9 0.4 0.7 1.7 0.0 3.1 2.3 1.8 2.1 4.3 5.2 1.8 22.9 14.3 1.8 6.6 0.0 1.6 30.2 2.4 1.3 2.7 2.4 4.2 24.5 1.0 5.5 2.1 9.2 4.2 0.0 13.3 3.9 23.6 2.3 0.0 25.4 3.4 4.1 0.8 0.3 74.2 2.1 0.2 1.8 15.0 0.2 0.2 0.0 12.1 4.3 2.0 3.0 0.7 0.2 1.3 11.4 2.2 4.3 6.1 6.6 1.0 1.4 2.2 1.7 0.7 0.4 4.5 0.2 0.4 5.0 1.2 ATP8A2 "ATPIB, ML-1" ENSG00000132932 "ATPase phospholipid transporting 8A2" Q9NTI2 13 25371974-26025851 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Lipid transport, Transport" Translocase "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 21.6;pituitary gland: 15.2;retina: 17.2" "Group enriched" "Detected in many" 6 "Excitatory neurons: 518.7;Inhibitory neurons: 727.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 19.9;JURKAT: 9.8;MOLT-4: 3.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039926, HPA040033" Supported Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" Nucleoplasm "HPA039926: AB_10794205, HPA040033: AB_2676809" "unprognostic (3.79e-2)" "unprognostic (4.28e-2)" "unprognostic (3.32e-2)" "unprognostic (1.95e-4)" "unprognostic (3.57e-2)" "unprognostic (1.89e-1)" "unprognostic (1.31e-2)" "unprognostic (2.97e-3)" "unprognostic (2.77e-1)" "unprognostic (3.66e-1)" "unprognostic (4.96e-4)" "unprognostic (1.24e-1)" "unprognostic (1.18e-2)" "unprognostic (4.20e-5)" "unprognostic (9.10e-2)" "unprognostic (2.95e-1)" "unprognostic (7.22e-2)" 0.1 2.1 5.5 0.3 6.7 0.0 0.6 8.0 21.6 0.2 0.0 0.4 0.3 0.6 1.8 0.0 0.0 0.1 0.1 8.7 19.3 0.3 0.0 0.8 0.6 12.8 4.6 0.2 0.6 0.0 15.2 0.2 12.1 0.1 0.2 17.2 0.1 0.0 0.3 0.1 0.3 0.1 0.2 0.3 0.6 2.9 6.6 1.0 0.1 0.1 0.2 0.2 0.0 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.0 0.0 0.0 0.2 1.5 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 19.9 0.1 0.0 0.0 0.0 0.6 0.5 9.8 0.0 0.0 1.7 0.1 3.9 0.0 2.0 0.0 0.7 0.0 2.7 0.9 0.2 0.0 3.2 0.0 0.2 0.2 0.1 0.2 0.0 0.4 0.2 0.0 1.0 0.3 0.4 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.5 0.7 0.0 0.0 0.0 0.0 0.2 0.1 5.5 6.7 8.0 21.6 8.7 19.3 12.8 4.6 12.1 0.2 6.6 6.8 0.7 0.0 12.2 9.4 0.8 1.0 0.2 0.3 0.0 21.5 1.5 0.3 2.5 1.5 0.4 0.0 95.9 1.5 0.4 0.0 0.0 0.3 39.0 1.2 23.6 2.6 0.0 0.8 518.7 0.0 0.4 1.7 1.1 0.9 5.1 3.7 0.0 0.0 3.2 21.9 727.7 0.0 0.0 0.0 0.7 30.3 0.9 0.3 0.0 9.4 0.0 7.2 1.0 88.4 24.7 0.0 0.0 1.2 0.1 0.2 0.0 1.3 0.3 91.6 13.1 0.3 0.8 19.8 12.5 0.0 0.4 1.1 1.8 10.1 0.1 0.1 ATP8B2 "ATPID, KIAA1137" ENSG00000143515 "ATPase phospholipid transporting 8B2" P98198 1 154325525-154351304 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 26.8;Excitatory neurons: 28.5;Inhibitory neurons: 31.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 6 "granulocytes: 2.8;T-cells: 3.7" "Cell line enhanced" "Detected in many" "ASC diff: 120.9;fHDF/TERT166: 112.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046680, HPA061103" Approved Supported "Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "Plasma membrane" "Nucleoli, Cytosol" "HPA046680: AB_2679749, HPA061103: " "unprognostic (1.68e-1)" "unprognostic (3.68e-1)" "unprognostic (8.40e-2)" "unprognostic (5.16e-2)" "unprognostic (4.52e-1)" "unprognostic (8.17e-2)" "unprognostic (2.27e-2)" "unprognostic (6.93e-3)" "unprognostic (2.57e-1)" "unprognostic (1.69e-1)" "prognostic favorable (1.60e-4)" "unprognostic (2.82e-1)" "unprognostic (1.89e-3)" "unprognostic (7.77e-3)" "unprognostic (6.58e-2)" "unprognostic (3.19e-2)" "prognostic unfavorable (5.29e-5)" 17.2 9.5 8.2 22.7 7.8 5.4 14.0 18.8 11.0 28.7 20.7 17.8 12.5 39.2 17.7 11.0 30.8 18.2 15.2 10.8 9.2 6.3 3.4 18.0 25.4 8.9 8.1 35.3 5.9 10.5 19.3 15.3 9.6 18.9 9.1 2.1 7.2 21.2 3.5 8.5 17.6 39.7 5.6 19.5 14.5 16.3 8.8 18.4 15.0 7.4 19.6 19.7 17.9 7.7 2.1 15.6 20.0 20.5 120.9 80.4 0.3 41.8 77.4 26.1 30.5 0.3 0.6 1.9 21.4 112.4 17.7 9.2 23.0 5.5 19.3 46.6 16.8 19.7 20.4 18.9 37.2 0.1 14.8 53.4 1.3 40.6 38.7 35.6 40.0 25.1 37.6 47.8 22.7 21.8 36.2 2.5 43.7 0.4 17.4 39.9 12.7 71.5 5.3 0.4 17.4 22.7 11.3 2.8 30.3 28.3 14.9 15.3 34.7 40.2 19.2 51.4 13.5 58.0 75.7 11.1 14.1 2.2 24.7 2.8 0.0 1.7 1.1 0.0 0.7 0.3 1.7 1.9 0.0 0.2 1.4 1.2 0.0 0.5 0.0 0.3 3.7 0.5 8.2 7.8 18.8 11.0 10.8 9.2 8.9 8.1 9.6 5.6 8.8 7.7 6.4 3.2 4.5 26.8 7.7 2.5 1.4 0.9 0.0 4.5 1.9 2.3 6.2 0.0 1.9 0.0 2.1 0.1 16.0 0.1 0.0 1.6 0.6 6.5 20.5 9.0 0.0 0.4 28.5 0.2 0.5 12.8 0.5 2.4 7.6 10.8 13.6 0.8 0.4 8.4 31.7 0.2 0.0 1.0 4.2 1.4 11.5 1.3 7.2 4.7 0.9 3.4 7.2 4.0 4.2 0.9 0.0 14.7 13.9 5.6 0.0 0.2 4.4 0.5 0.0 9.5 11.2 2.6 4.3 0.6 1.6 0.3 17.2 6.7 0.1 0.8 ATR "FRP1, MEC1, SCKL, SCKL1" ENSG00000175054 "ATR serine/threonine kinase" Q13535 3 142449007-142578733 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "DNA damage, DNA repair" "DNA-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 93.0;Inhibitory neurons: 94.4;Microglial cells: 73.1;Oligodendrocyte precursor cells: 65.4;Oligodendrocytes: 71.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054320 Supported "Nucleoplasm,Golgi apparatus" No No "Cluster 15: NK-cells - Transcription" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Golgi apparatus" "HPA054320: AB_2682448" "unprognostic (1.47e-1)" "unprognostic (8.90e-2)" "unprognostic (2.90e-1)" "unprognostic (4.23e-2)" "unprognostic (2.25e-2)" "unprognostic (6.42e-2)" "prognostic unfavorable (8.39e-5)" "unprognostic (3.44e-1)" "unprognostic (1.67e-1)" "unprognostic (3.02e-1)" "prognostic unfavorable (1.23e-5)" "unprognostic (1.94e-1)" "unprognostic (5.61e-2)" "unprognostic (1.06e-1)" "unprognostic (3.55e-1)" "unprognostic (1.69e-2)" "unprognostic (1.43e-1)" 3.0 8.6 0.7 4.1 1.1 1.2 3.2 0.9 1.4 3.8 3.7 2.7 1.7 3.3 2.3 3.1 3.3 3.4 2.3 1.2 1.9 3.7 3.6 2.9 4.8 1.5 1.2 2.7 3.8 5.2 3.7 3.1 1.4 3.0 2.9 2.9 3.5 2.5 2.9 2.7 3.1 3.2 1.0 4.2 2.8 5.2 1.2 4.9 5.0 1.4 4.6 4.1 2.7 1.2 28.6 13.2 7.1 7.0 9.6 13.6 8.8 14.8 8.4 10.1 9.7 6.4 6.8 19.9 14.6 10.1 14.6 16.1 10.9 12.8 15.0 7.5 7.9 11.9 8.2 4.1 4.2 20.5 5.3 9.8 4.8 9.5 10.3 5.8 11.6 8.7 8.2 7.5 9.6 7.5 13.9 2.6 7.3 15.6 9.6 11.8 12.5 13.5 6.3 11.1 5.2 5.1 28.6 8.3 8.0 7.8 12.0 5.4 14.6 10.5 4.9 12.3 15.2 10.8 7.4 18.5 13.8 6.5 8.5 0.0 0.3 0.0 0.5 0.4 1.0 0.1 0.3 0.5 0.7 0.3 0.4 0.4 0.0 1.3 0.2 0.2 0.4 0.2 0.7 1.1 0.9 1.4 1.2 1.9 1.5 1.2 1.4 1.0 1.2 1.2 11.5 6.4 10.6 39.2 22.4 4.0 7.2 8.8 14.2 14.1 9.2 6.5 7.6 5.7 10.1 3.7 37.5 7.7 14.9 3.5 0.0 5.9 16.4 18.8 18.6 10.2 7.7 14.5 93.0 4.9 3.6 8.3 14.8 10.3 1.3 16.3 7.9 7.3 6.4 8.4 94.4 4.8 14.2 9.4 4.0 8.7 6.5 12.8 10.6 73.1 12.0 6.0 9.2 65.4 71.9 6.4 1.8 7.2 23.1 8.1 1.9 6.5 25.4 23.6 0.0 14.6 9.8 50.1 18.5 14.7 4.5 5.1 15.1 13.8 7.6 6.1 ATXN1 "ATX1, D6S504E, SCA1" ENSG00000124788 "Ataxin 1" P54253 6 16299112-16761491 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor, RNA-binding" "Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 582.5;Inhibitory neurons: 519.0;Oligodendrocyte precursor cells: 318.2;Oligodendrocytes: 466.8" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebral cortex: 14.4" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "U-266/70: 30.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008335, HPA070756" Approved Supported Nucleoplasm,Nucleoli,Cytosol Yes No "Cluster 9: Neutrophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 29: U-266 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "Nucleoli, Cytosol" "HPA008335: AB_1845129, HPA070756: AB_2686306" "unprognostic (1.01e-1)" "unprognostic (4.77e-2)" "unprognostic (1.23e-1)" "unprognostic (5.64e-3)" "unprognostic (4.54e-1)" "unprognostic (1.95e-2)" "unprognostic (7.74e-2)" "unprognostic (4.51e-2)" "unprognostic (4.06e-1)" "unprognostic (1.11e-2)" "unprognostic (3.87e-2)" "unprognostic (2.69e-2)" "unprognostic (1.41e-3)" "unprognostic (1.67e-3)" "unprognostic (2.33e-1)" "unprognostic (1.06e-1)" "unprognostic (3.29e-3)" 4.1 4.0 3.2 5.9 5.3 2.6 4.1 0.0 14.4 8.4 0.0 8.8 3.8 10.9 4.3 5.0 6.2 5.7 5.8 8.4 0.0 4.1 4.7 6.9 4.2 0.0 1.3 5.4 4.8 5.5 6.5 4.9 0.0 7.4 3.8 13.9 4.6 6.2 14.6 5.7 4.8 7.5 0.0 5.7 5.3 3.0 3.9 2.6 6.1 14.8 3.1 6.7 6.6 0.8 4.5 2.6 0.9 0.0 4.4 5.9 5.8 4.8 11.2 2.9 3.3 2.8 2.8 0.2 6.3 9.3 3.7 4.2 0.3 3.0 4.2 2.6 4.7 0.7 4.4 9.0 7.0 4.2 7.0 4.6 5.7 6.1 5.1 11.2 5.9 0.9 0.0 5.3 2.4 2.3 0.3 4.8 0.9 1.4 4.3 0.3 5.8 4.0 4.0 7.6 0.3 2.5 4.4 5.5 9.1 8.4 3.6 7.2 9.1 4.0 6.1 4.8 4.4 30.7 19.2 0.2 2.6 4.3 10.0 0.2 0.5 0.1 0.7 0.4 0.5 0.1 0.5 0.7 0.2 0.0 0.0 0.4 1.3 0.0 0.2 0.1 0.4 0.3 3.2 5.3 0.0 14.4 8.4 0.0 0.0 1.3 0.0 0.0 3.9 0.8 16.0 48.1 25.9 206.3 20.7 91.4 72.2 22.8 48.9 39.8 20.7 14.4 35.9 25.8 26.0 11.0 100.1 0.6 48.4 23.6 7.9 16.7 4.3 80.5 144.4 21.7 1.2 5.7 582.5 8.5 4.0 32.9 22.4 75.8 38.7 67.4 17.2 25.2 22.4 38.7 519.0 16.5 2.0 39.6 79.1 3.3 10.5 41.7 32.0 217.4 42.3 24.1 33.0 318.2 466.8 32.3 16.3 28.2 82.6 56.6 13.9 8.8 33.2 99.9 52.6 19.0 41.6 1.0 6.9 60.9 48.7 0.4 61.5 6.4 7.7 63.8 ATXN1L BOAT1 ENSG00000224470 "Ataxin 1 like" P0C7T5 16 71845976-71885268 "Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Late spermatids: 263.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062596, HPA062789" Enhanced Nucleoplasm NA NA "Cluster 35: T-regs - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "HPA062596: AB_2684802, HPA062789: AB_2684868" "unprognostic (1.51e-1)" "unprognostic (1.73e-2)" "unprognostic (1.39e-1)" "unprognostic (1.67e-1)" "unprognostic (3.01e-2)" "unprognostic (1.01e-1)" "unprognostic (1.68e-1)" "unprognostic (1.14e-1)" "unprognostic (1.00e-1)" "unprognostic (1.04e-1)" "unprognostic (8.13e-2)" "unprognostic (1.99e-1)" "prognostic favorable (5.33e-8)" "unprognostic (1.61e-1)" "unprognostic (1.42e-1)" "unprognostic (5.30e-2)" "prognostic unfavorable (8.42e-4)" 14.0 8.0 11.5 9.9 12.7 39.5 10.9 9.0 9.7 11.1 5.6 10.4 8.2 12.3 7.3 9.7 10.9 9.0 9.5 9.3 9.4 18.7 6.6 12.0 10.0 10.9 11.7 12.7 12.5 16.5 5.2 10.8 10.3 8.1 9.2 8.0 9.4 10.4 10.4 12.1 9.4 12.9 10.3 11.8 10.0 12.2 12.5 12.8 11.9 13.7 10.5 8.9 7.4 11.9 11.8 15.7 15.7 11.5 18.1 8.9 18.4 9.8 10.8 17.4 13.2 22.6 12.9 13.2 15.0 15.4 8.0 20.3 13.4 14.9 18.9 3.6 11.9 9.7 17.7 15.9 13.5 11.9 19.0 12.8 18.6 19.8 14.2 11.4 16.0 17.0 11.1 10.2 10.4 33.6 20.2 11.7 14.3 9.3 7.4 21.4 15.9 15.8 12.1 16.4 8.3 14.2 19.5 10.2 11.9 16.4 16.0 12.5 19.4 19.0 19.9 12.1 13.3 23.0 20.8 30.7 11.8 7.9 16.3 0.6 0.3 0.3 0.4 0.4 0.3 0.3 0.3 0.4 0.2 0.2 0.5 0.5 0.4 0.4 0.2 0.1 0.7 0.3 11.5 12.7 9.0 9.7 9.3 9.4 10.9 11.7 10.3 10.3 12.5 11.9 11.1 0.0 10.6 4.2 14.9 22.8 15.3 11.4 14.2 11.2 16.0 10.2 15.7 14.3 9.5 14.7 14.6 8.3 19.9 15.2 17.6 11.9 44.2 19.1 15.0 14.2 7.8 5.7 6.8 11.8 7.9 11.0 5.6 35.4 12.7 8.0 14.3 12.3 8.5 15.2 5.7 8.7 8.2 14.3 25.2 263.0 14.9 11.8 12.4 5.6 16.9 6.3 29.9 3.5 9.1 14.4 19.6 12.8 16.0 18.3 13.3 15.8 9.9 17.2 13.1 15.5 14.3 22.4 21.1 13.1 24.9 11.5 15.8 8.0 10.6 28.4 ATXN2L "A2D, A2lp" ENSG00000168488 "Ataxin 2 like" Q8WWM7 16 28823035-28837237 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041506, HPA043391, HPA071955" Approved Enhanced Cytosol NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 44: Endometrium - Transcription" Cytosol "HPA041506: AB_2677521, HPA043391: AB_2678459, HPA071955: AB_2686478" "unprognostic (1.64e-2)" "unprognostic (1.72e-1)" "unprognostic (7.33e-3)" "unprognostic (1.03e-2)" "unprognostic (3.11e-1)" "unprognostic (6.63e-2)" "prognostic unfavorable (9.85e-4)" "unprognostic (5.59e-2)" "unprognostic (7.56e-2)" "unprognostic (1.02e-1)" "unprognostic (2.11e-1)" "unprognostic (2.83e-2)" "prognostic unfavorable (7.99e-7)" "unprognostic (1.79e-1)" "unprognostic (1.61e-2)" "unprognostic (7.22e-2)" "unprognostic (2.98e-1)" 67.8 78.2 80.2 51.6 86.2 82.9 65.3 89.9 116.8 83.3 72.7 75.6 43.8 71.3 20.9 81.9 77.8 29.2 68.8 82.2 82.2 85.7 96.1 85.9 62.7 83.2 80.4 81.3 96.8 33.7 116.4 39.0 83.4 80.6 27.0 56.5 70.1 27.9 63.8 76.9 86.3 33.4 75.5 117.0 82.6 178.9 83.5 52.5 83.0 23.7 46.9 75.5 77.7 86.0 77.8 97.6 99.0 112.1 59.9 61.5 116.1 76.3 73.7 82.1 91.3 124.1 90.1 178.6 95.4 54.4 128.6 110.2 93.9 76.9 90.5 140.9 83.3 119.5 124.3 127.4 107.5 135.9 161.2 78.8 90.1 116.4 166.1 72.4 73.2 174.4 158.9 219.9 68.4 109.9 166.1 228.0 100.6 46.9 67.2 216.4 68.5 125.6 48.9 79.6 102.8 81.9 44.6 83.5 95.8 62.3 91.3 141.0 88.2 101.2 83.6 65.8 106.2 311.9 238.1 159.4 76.3 128.1 119.6 0.4 2.1 1.4 1.6 1.9 1.6 4.3 1.9 2.0 1.6 2.9 1.8 2.3 2.4 1.9 1.6 5.6 1.7 1.1 80.2 86.2 89.9 116.8 82.2 82.2 83.2 80.4 83.4 75.5 83.5 86.0 30.2 28.9 33.3 26.1 48.2 36.6 25.1 20.2 66.0 31.6 29.8 26.3 2.1 21.5 19.8 20.2 45.9 23.0 39.1 19.8 1.9 17.8 71.7 37.7 34.9 27.8 24.6 23.1 37.3 20.2 21.9 20.8 31.6 53.1 25.9 23.4 27.1 14.7 24.8 26.9 37.5 23.4 14.2 29.3 33.3 25.7 21.5 36.5 8.8 24.4 26.4 10.0 33.0 18.6 31.5 32.2 19.4 19.9 65.1 33.0 19.7 4.8 18.8 48.9 13.1 28.9 22.1 83.9 28.3 46.3 31.1 34.3 48.4 24.5 23.4 27.4 AVPR2 "DIR, DIR3, V2R" ENSG00000126895 "Arginine vasopressin receptor 2" P30518 X 153902531-153907166 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Diabetes insipidus, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 8.1" "Group enriched" "Detected in some" 4 "Adipocytes: 48.0;Collecting duct cells: 49.7;Endothelial cells: 17.4" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 7 "cerebellum: 3.9" "Group enriched" "Detected in some" 28 "intermediate monocyte: 3.6;non-classical monocyte: 3.2" "Lineage enriched" "Detected in single" 29 "monocytes: 3.6" "Cell line enhanced" "Detected in some" "EFO-21: 3.2;SCLC-21H: 3.7;U-266/84: 3.7;U-698: 3.6" "Not detected" "Not detected" "Region enriched" "Detected in single" 22 "cerebellum: 6.8" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 16: U-266 - Nucleosome" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (3.05e-2)" "unprognostic (5.62e-2)" "unprognostic (1.99e-4)" "unprognostic (2.50e-4)" "unprognostic (2.76e-1)" "unprognostic (7.10e-6)" "unprognostic (3.80e-3)" "unprognostic (1.17e-1)" "unprognostic (2.20e-1)" "unprognostic (2.56e-2)" "unprognostic (4.21e-2)" "unprognostic (1.91e-1)" "unprognostic (1.33e-1)" "unprognostic (1.08e-2)" "unprognostic (1.87e-1)" "unprognostic (4.38e-1)" "unprognostic (9.83e-2)" 5.2 0.2 0.1 0.2 0.0 0.8 3.1 3.9 0.1 1.0 0.5 0.8 0.6 0.9 0.1 0.6 1.6 1.0 5.1 0.1 0.0 8.1 0.0 1.3 1.0 0.3 0.5 0.2 0.6 0.7 0.1 0.2 0.4 0.7 0.2 0.0 0.7 0.6 3.1 1.5 0.8 0.8 0.1 0.3 0.7 0.2 0.1 0.4 0.9 4.0 0.3 0.8 1.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 1.6 3.2 0.0 0.5 0.0 0.0 0.0 0.0 1.1 0.1 1.2 0.6 0.0 0.0 1.6 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.5 0.0 0.0 0.8 1.0 0.1 0.0 0.0 1.4 0.6 1.4 0.0 0.0 3.7 0.7 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.1 0.6 3.7 3.6 0.0 0.9 0.0 0.0 0.1 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.1 0.1 0.0 3.9 0.1 0.1 0.0 0.3 0.5 0.4 0.1 0.1 0.2 48.0 3.2 1.3 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.5 0.4 1.5 0.0 0.0 49.7 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.1 0.0 17.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 1.3 0.0 0.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 8.6 0.8 0.0 0.0 0.1 1.3 0.0 0.1 0.5 0.0 0.1 AXL "ARK, JTK11, Tyro7, UFO" ENSG00000167601 "AXL receptor tyrosine kinase" P30530 19 41219223-41261766 "Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Differentiation, Host-virus interaction, Immunity, Innate immunity" "Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "FDA approved drug targets, Oncogene, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 147.2;Kupffer cells: 187.5;Langerhans cells: 185.5;Prostatic glandular cells: 123.4;Sertoli cells: 210.4;Smooth muscle cells: 171.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 11.1;plasmacytoid DC: 25.7" "Group enriched" "Detected in many" 12 "dendritic cells: 25.7;NK-cells: 11.1" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 501.2;U-251 MG: 540.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032501, HPA037422, HPA037423, HPA075217" Uncertain Supported "Vesicles,Plasma membrane,Actin filaments" NA Yes 12100000 72000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" "Vesicles, Actin filaments" "CAB032501: AB_2062572, HPA037422: AB_10672347, HPA037423: AB_2675470, HPA075217: " "unprognostic (2.20e-1)" "unprognostic (2.02e-1)" "unprognostic (6.79e-3)" "unprognostic (1.01e-1)" "unprognostic (1.40e-1)" "unprognostic (8.49e-3)" "unprognostic (2.42e-1)" "unprognostic (1.74e-1)" "unprognostic (3.15e-2)" "unprognostic (2.82e-2)" "unprognostic (9.57e-3)" "unprognostic (1.98e-1)" "prognostic unfavorable (2.53e-7)" "unprognostic (1.16e-3)" "unprognostic (1.52e-2)" "unprognostic (5.56e-2)" "unprognostic (4.83e-3)" 43.6 18.8 17.5 15.5 22.6 1.7 26.6 19.7 17.7 36.1 12.4 42.5 11.7 34.4 8.7 17.6 25.4 22.4 26.7 16.6 18.8 9.8 15.0 25.9 6.2 26.8 20.6 24.7 6.3 10.7 7.3 34.2 22.1 19.2 12.6 5.8 10.6 24.6 9.4 20.0 19.0 37.1 20.9 37.7 21.4 18.6 24.0 7.2 16.6 11.3 5.0 32.5 25.2 21.9 408.0 160.0 9.7 1.3 34.6 34.7 0.5 314.5 280.2 450.9 278.2 8.5 185.5 0.2 124.7 501.2 235.3 33.3 0.4 211.8 384.8 0.7 0.3 0.0 100.4 6.3 125.0 0.3 0.3 26.4 3.8 266.7 409.5 254.8 169.8 0.1 15.8 0.5 284.6 0.5 0.2 0.4 4.1 1.0 76.3 0.2 165.3 0.3 202.3 0.2 0.1 0.1 81.5 0.6 1.8 57.4 0.9 7.2 351.8 317.8 214.6 307.7 540.8 0.5 0.9 1.0 211.5 0.5 241.8 1.5 0.3 0.2 0.1 0.4 0.2 0.1 0.3 0.1 6.0 0.1 0.3 0.3 0.3 11.1 0.2 25.7 0.4 0.3 17.5 22.6 19.7 17.7 16.6 18.8 26.8 20.6 22.1 20.9 24.0 21.9 13.5 9.6 3.6 35.9 1.9 41.7 88.3 10.3 3.4 0.5 2.3 14.2 8.6 1.5 4.4 5.5 0.0 4.2 0.8 0.1 0.0 6.9 8.7 6.0 45.8 17.7 0.0 0.0 0.8 0.2 2.1 147.2 1.5 5.4 0.0 17.3 11.0 1.2 28.8 1.7 1.1 0.1 2.0 187.5 185.5 5.5 61.5 61.4 26.6 30.9 3.1 26.8 0.0 11.1 0.5 14.5 0.1 79.7 0.8 123.4 0.3 0.1 2.8 1.2 210.4 38.1 171.1 1.9 2.0 1.2 29.1 11.5 3.6 2.5 0.1 28.0 B3GNT5 "B3GN-T5, beta3Gn-T5" ENSG00000176597 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5" Q9BYG0 3 183253253-183298504 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Developmental protein, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 76.5" "Cell type enhanced" "Detected in many" "Adipocytes: 151.2;Distal enterocytes: 150.4;Squamous epithelial cells: 169.9;Syncytiotrophoblasts: 157.9;Urothelial cells: 144.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "neutrophil: 5.6" "Lineage enriched" "Detected in many" 6 "granulocytes: 5.6" "Cell line enhanced" "Detected in many" "GAMG: 82.4;HBEC3-KT: 70.3;hTCEpi: 83.5" "Region enriched" "Detected in many" 4 "cerebellum: 14.7" "Low region specificity" "Detected in all" HPA017292 Uncertain Approved Nucleoli NA NA 28000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoli "HPA017292: AB_1845237" "unprognostic (2.17e-1)" "unprognostic (5.73e-2)" "unprognostic (1.07e-2)" "unprognostic (4.83e-3)" "unprognostic (1.89e-1)" "unprognostic (3.08e-2)" "prognostic unfavorable (5.09e-4)" "unprognostic (7.10e-3)" "unprognostic (7.78e-2)" "unprognostic (8.48e-2)" "prognostic unfavorable (7.23e-6)" "unprognostic (4.20e-1)" "prognostic unfavorable (1.30e-7)" "unprognostic (1.18e-2)" "unprognostic (2.71e-1)" "unprognostic (3.53e-2)" "unprognostic (8.10e-3)" 11.9 2.4 3.3 13.7 3.5 76.5 5.5 2.3 3.2 6.0 0.9 22.6 38.2 5.1 9.1 37.5 9.6 21.3 3.5 3.7 4.0 3.8 3.3 15.0 1.1 5.6 3.8 4.6 7.5 3.5 5.7 13.9 4.6 7.9 19.6 1.2 10.1 3.3 7.4 10.3 42.0 6.7 4.3 1.6 11.3 7.3 3.5 7.6 5.2 4.5 5.3 24.2 13.8 5.5 46.2 4.4 23.8 14.7 19.5 57.0 21.5 0.7 1.1 4.6 3.8 9.0 23.6 0.0 2.7 0.1 82.4 20.6 24.7 70.3 3.9 0.1 15.3 2.4 1.9 0.0 24.8 23.4 10.9 27.0 83.5 3.7 62.1 6.2 43.4 0.1 26.6 0.1 38.1 0.0 0.1 7.6 10.1 26.9 38.5 7.3 12.0 0.1 14.4 12.7 1.0 22.6 12.7 0.1 5.3 10.6 0.0 28.0 64.6 1.1 9.0 1.4 11.0 0.0 0.0 0.0 8.8 54.1 23.8 0.0 1.0 1.0 0.0 0.1 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.2 0.3 3.3 3.5 2.3 3.2 3.7 4.0 5.6 3.8 4.6 4.3 3.5 5.5 151.2 6.4 17.5 2.3 1.2 65.1 70.2 35.8 101.3 10.0 18.4 10.4 2.2 21.5 40.5 5.5 22.9 31.0 1.9 150.4 1.9 18.0 13.4 58.0 13.1 26.3 38.2 6.3 1.8 11.8 10.7 9.2 70.3 55.3 14.0 2.4 2.2 0.6 29.6 3.3 1.5 88.2 34.6 15.6 123.2 26.5 1.5 76.8 12.4 80.6 9.4 3.1 0.0 4.5 0.8 35.7 126.4 0.4 1.4 43.1 74.9 4.8 118.5 13.1 0.0 23.6 5.4 7.9 0.8 169.9 84.8 157.9 4.3 0.2 36.2 144.4 BABAM2 "BRCC4, BRCC45, BRE" ENSG00000158019 "BRISC and BRCA1 A complex member 2" Q9NXR7 2 27889941-28338901 "Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, DNA damage, DNA repair, Mitosis, Ubl conjugation pathway" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "adrenal gland: 380.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 46.1;Distal tubular cells: 84.1;Ductal cells: 53.4;Proximal tubular cells: 84.1;Syncytiotrophoblasts: 48.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017926, HPA048867" Enhanced Supported Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 7: Non-specific - Mitochondria" Cytosol "HPA017926: AB_1845443, HPA048867: " "unprognostic (1.28e-1)" "unprognostic (2.30e-1)" "unprognostic (1.53e-3)" "unprognostic (1.61e-3)" "unprognostic (1.89e-1)" "unprognostic (2.68e-3)" "prognostic unfavorable (6.33e-4)" "unprognostic (1.03e-1)" "unprognostic (2.38e-2)" "unprognostic (8.98e-2)" "unprognostic (2.13e-1)" "unprognostic (6.52e-2)" "unprognostic (4.41e-3)" "unprognostic (1.02e-1)" "unprognostic (4.74e-2)" "unprognostic (2.91e-2)" "unprognostic (1.22e-2)" 30.9 380.0 22.1 21.2 25.2 41.6 27.5 22.9 28.4 31.8 24.6 27.2 18.3 32.1 33.5 24.5 31.0 32.0 54.2 27.4 28.4 54.2 28.6 24.9 20.5 22.4 23.4 36.3 21.7 35.1 32.8 23.3 30.9 24.9 26.2 26.2 20.5 29.0 73.8 25.9 23.0 36.9 18.6 28.6 25.2 27.2 21.1 21.4 24.0 54.8 26.3 31.2 25.3 21.6 39.5 42.8 33.6 35.7 42.4 56.5 33.2 19.4 49.0 36.0 37.2 36.5 39.4 44.4 64.1 47.3 28.9 25.7 27.7 50.9 52.5 37.8 37.1 53.2 17.5 40.9 61.3 28.1 41.5 139.0 43.6 50.3 51.9 45.1 38.7 41.0 27.7 47.3 50.7 33.3 32.8 34.2 25.7 51.4 27.8 29.9 53.6 42.9 104.2 20.4 22.0 35.0 23.0 39.9 40.3 33.9 28.6 36.5 31.7 34.1 45.2 31.7 27.1 53.5 55.8 57.7 63.5 75.6 36.4 106.3 65.6 27.8 57.9 53.1 64.6 50.6 48.7 55.3 86.3 37.6 45.7 43.6 34.3 59.0 55.3 34.4 62.2 56.9 22.1 25.2 22.9 28.4 27.4 28.4 22.4 23.4 30.9 18.6 21.1 21.6 26.7 3.2 19.6 0.0 7.0 0.0 0.0 0.0 0.0 0.0 16.0 18.0 0.0 0.0 5.6 40.5 0.0 46.1 19.0 0.0 84.1 53.4 0.0 22.6 17.4 10.0 0.0 0.0 0.0 44.3 36.8 11.0 0.0 32.5 31.5 23.1 0.0 0.0 38.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 0.0 0.0 25.8 0.0 0.0 0.0 0.0 20.2 0.0 0.0 4.0 0.0 0.0 84.1 8.7 0.0 0.0 0.0 10.1 0.0 0.0 0.0 0.0 48.2 9.7 44.5 0.0 0.0 BAG1 ENSG00000107262 "BAG cochaperone 1" Q99933 9 33247820-33264720 "Cancer-related genes, Predicted intracellular proteins" Apoptosis Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 1043.2;Late spermatids: 2944.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HeLa: 437.5;NB-4: 417.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002486, HPA018121, HPA073236" Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 34: Spermatids - Unknown function" Nucleoplasm Cytosol "CAB002486: AB_563422, HPA018121: AB_1845255, HPA073236: " "unprognostic (4.49e-3)" "unprognostic (4.52e-2)" "unprognostic (2.33e-2)" "unprognostic (1.32e-3)" "unprognostic (5.46e-2)" "unprognostic (3.67e-3)" "unprognostic (2.10e-1)" "unprognostic (1.34e-2)" "unprognostic (4.62e-2)" "unprognostic (7.21e-2)" "unprognostic (4.24e-1)" "unprognostic (2.23e-1)" "prognostic favorable (2.22e-16)" "unprognostic (4.45e-2)" "unprognostic (4.03e-1)" "unprognostic (7.64e-3)" "unprognostic (1.07e-2)" 79.7 76.3 96.6 36.3 106.7 85.0 72.3 102.2 112.3 65.0 106.0 122.5 59.3 59.8 53.9 103.2 54.8 39.1 192.9 86.4 102.8 151.6 83.4 82.5 35.5 107.4 105.2 45.6 91.7 139.6 99.3 47.1 98.8 88.0 75.4 82.2 97.4 68.4 297.7 113.8 66.1 42.7 100.2 66.0 102.5 87.9 104.3 45.1 71.6 206.1 55.2 121.5 78.8 101.6 56.0 56.1 46.8 103.3 69.9 40.9 63.6 46.5 64.6 68.4 69.8 39.7 54.1 181.2 33.6 46.6 24.5 69.8 54.8 37.9 45.0 96.5 52.1 90.2 437.5 62.5 58.9 210.1 110.0 41.5 205.6 32.3 76.8 32.2 82.4 48.0 108.7 92.1 57.8 89.7 152.4 417.0 90.8 73.9 81.2 78.7 63.7 119.6 87.1 164.8 149.1 88.5 192.7 176.9 46.0 18.7 80.5 261.8 44.1 30.5 37.8 89.9 78.0 74.9 125.3 100.4 25.5 114.1 17.7 29.1 20.7 57.9 10.0 22.2 9.0 14.7 11.2 11.9 26.1 25.6 15.7 9.1 10.2 15.3 22.3 33.9 15.2 10.2 96.6 106.7 102.2 112.3 86.4 102.8 107.4 105.2 98.8 100.2 104.3 101.6 107.7 89.8 67.5 5.2 69.4 429.9 279.4 193.3 172.4 84.0 134.1 123.6 144.4 127.2 157.0 218.8 58.4 154.7 113.7 211.4 397.2 135.6 1043.2 109.3 72.2 86.6 198.1 259.1 5.9 189.0 59.9 79.4 104.5 193.3 41.9 36.7 66.8 72.8 104.9 38.7 7.1 287.8 170.9 86.4 162.7 2944.9 85.7 93.9 163.7 2.8 81.0 123.9 88.6 4.5 9.7 131.1 259.2 88.8 110.3 505.4 247.9 286.1 71.8 131.3 98.6 98.5 109.9 87.9 64.4 261.1 561.5 245.9 69.6 103.7 222.4 531.4 BARHL2 ENSG00000143032 "BarH like homeobox 2" Q9NY43 1 90711539-90717302 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "brain: 27.4" "Cell type enriched" "Detected in some" 4 "Horizontal cells: 23.5" "Not detected" "Not detected" "Region enriched" "Detected in many" 14 "cerebellum: 27.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 1.0;HEK 293: 3.7;HMC-1: 1.0" "Region enriched" "Detected in many" 5 "cerebellum: 12.9" "Region enriched" "Detected in some" 20 "cerebellum: 24.6" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 62: Horizontal cells - Visual perception" "unprognostic (1.83e-1)" "unprognostic (1.73e-1)" "unprognostic (6.80e-2)" "unprognostic (3.10e-1)" "unprognostic (1.60e-1)" 0.0 0.0 0.2 0.0 0.1 0.0 0.0 27.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.1 1.9 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 2.3 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 3.7 0.5 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 27.4 0.7 0.0 1.2 0.1 1.9 1.9 0.3 2.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 4.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 BAZ2B WALp4 ENSG00000123636 "Bromodomain adjacent to zinc finger domain 2B" Q9UIF8 2 159318979-159616569 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 477.3;Oligodendrocytes: 604.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 115.8;neutrophil: 213.2" "Lineage enriched" "Detected in all" 8 "granulocytes: 213.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019819, HPA059292" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 12: NES - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm Cytosol "HPA019819: AB_1845282, HPA059292: AB_2683968" "unprognostic (2.27e-1)" "unprognostic (1.67e-1)" "unprognostic (5.24e-2)" "unprognostic (1.23e-1)" "unprognostic (1.37e-2)" "unprognostic (4.94e-3)" "unprognostic (1.19e-1)" "unprognostic (5.64e-2)" "unprognostic (5.49e-3)" "unprognostic (9.01e-2)" "unprognostic (2.29e-1)" "unprognostic (1.44e-1)" "unprognostic (1.27e-1)" "unprognostic (2.14e-1)" "unprognostic (3.30e-1)" "unprognostic (1.06e-2)" "unprognostic (2.14e-2)" 20.6 23.8 23.0 18.1 43.7 36.7 22.1 57.4 26.8 23.8 3.6 18.2 17.1 33.6 19.7 22.1 24.4 26.1 18.4 21.8 41.4 17.3 16.8 24.7 14.7 45.3 29.1 42.4 19.3 24.6 17.5 20.5 47.7 18.4 16.4 52.0 23.4 19.8 18.4 17.5 18.5 23.5 26.0 20.9 17.0 26.4 43.7 21.5 25.4 22.3 13.6 20.9 14.7 75.3 7.4 14.7 48.4 29.4 14.2 22.8 8.4 15.3 18.7 8.2 9.6 22.1 19.9 12.4 25.8 15.0 8.4 16.6 19.4 20.7 13.0 4.5 11.1 24.7 26.9 3.1 9.3 16.3 17.0 18.0 22.2 20.6 22.2 30.4 42.5 8.3 25.7 2.3 13.1 9.1 5.6 10.5 16.1 1.5 12.4 13.1 15.7 8.8 16.4 26.2 32.1 27.9 30.3 3.7 18.5 25.0 5.8 46.7 42.6 14.9 30.1 6.5 10.3 9.0 1.0 14.0 14.1 17.5 10.0 115.8 27.4 36.4 10.1 12.0 8.3 6.5 6.1 10.5 17.7 9.6 4.1 6.6 213.2 19.7 11.3 24.5 7.1 6.0 23.0 43.7 57.4 26.8 21.8 41.4 45.3 29.1 47.7 26.0 43.7 75.3 105.3 99.3 148.0 477.3 34.3 32.6 70.1 35.8 66.0 91.8 56.4 38.9 60.8 61.5 71.5 68.0 310.6 18.5 40.1 45.4 9.8 55.5 158.0 69.8 63.9 82.5 99.9 42.1 180.4 38.9 7.2 54.9 59.7 118.9 73.9 71.9 71.0 29.4 25.5 94.2 177.3 52.1 36.7 58.0 37.1 35.4 59.4 76.6 14.2 289.5 81.4 87.3 41.2 300.6 604.3 54.3 55.5 35.0 42.2 50.0 51.7 12.4 73.3 332.3 13.1 74.9 54.1 98.2 20.7 49.6 37.5 26.7 38.9 83.2 48.6 91.6 BBIP1 "bA348N5.3, BBIP10, BBS18, NCRNA00081" ENSG00000214413 "BBSome interacting protein 1" A8MTZ0 10 110898730-110919201 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Transport" "Bardet-Biedl syndrome, Ciliopathy, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 102.8" "Group enriched" "Detected in all" 4 "Early spermatids: 597.4;Late spermatids: 501.6;Spermatocytes: 399.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA055206 Approved NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA055206: AB_2682737" "unprognostic (6.05e-2)" "unprognostic (1.61e-2)" "unprognostic (1.50e-1)" "unprognostic (6.25e-3)" "unprognostic (3.08e-2)" "unprognostic (1.43e-1)" "unprognostic (2.65e-2)" "unprognostic (6.26e-2)" "unprognostic (2.60e-2)" "unprognostic (3.00e-2)" "unprognostic (6.79e-3)" "unprognostic (3.90e-2)" "unprognostic (1.06e-1)" "unprognostic (2.16e-1)" "unprognostic (1.94e-1)" "unprognostic (1.81e-1)" "unprognostic (3.85e-2)" 17.6 24.9 25.8 16.0 29.9 10.1 15.5 29.8 41.2 18.7 23.7 16.6 10.3 16.6 25.3 10.5 20.0 12.3 20.4 25.3 26.9 29.8 23.5 14.1 16.4 28.8 26.9 19.5 13.8 19.0 25.6 13.8 29.0 19.2 10.7 50.1 10.5 16.2 15.5 7.3 12.4 16.0 27.2 16.7 14.3 102.8 26.6 17.8 21.7 10.1 16.6 16.2 12.9 37.2 22.1 28.9 33.0 34.0 41.4 51.0 9.8 27.2 56.4 30.9 42.7 14.4 26.9 13.3 19.2 44.9 31.4 21.5 23.9 30.1 47.5 26.9 28.6 22.0 28.3 18.9 54.4 18.9 37.0 31.8 27.1 42.4 75.7 68.9 50.3 23.7 16.5 49.8 37.0 13.9 23.8 27.0 14.0 15.3 18.1 10.5 59.7 18.8 48.6 13.9 24.9 39.6 20.7 9.1 45.4 21.1 10.4 16.9 36.5 22.3 27.2 27.3 38.2 27.9 26.0 19.9 63.4 33.5 17.6 25.5 11.2 47.6 9.7 15.0 11.5 8.2 14.5 12.0 9.5 7.2 17.6 14.9 53.6 7.8 13.0 8.4 18.8 7.4 25.8 29.9 29.8 41.2 25.3 26.9 28.8 26.9 29.0 27.2 26.6 37.2 32.3 25.6 10.0 25.8 24.2 11.2 36.2 41.4 17.1 32.3 13.9 16.3 18.5 22.8 24.3 22.0 31.3 19.3 21.4 9.5 105.7 35.8 597.4 60.4 27.1 26.4 16.9 18.3 58.8 34.5 25.6 27.7 14.3 24.4 16.5 21.0 25.4 22.1 20.0 45.4 52.6 18.4 50.8 22.4 15.8 501.6 46.6 22.4 23.2 14.0 27.1 52.4 26.8 27.6 67.5 36.0 12.0 33.8 32.2 21.6 13.5 69.4 75.7 63.8 52.6 46.0 32.7 399.5 36.5 12.5 11.9 12.3 27.2 21.0 10.0 29.7 BBOF1 "C14orf45, CCDC176, FBB10" ENSG00000119636 "Basal body orientation factor 1" Q8ND07 14 74019349-74082863 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 38.6" "Group enriched" "Detected in many" 4 "Early spermatids: 239.3;Endometrial ciliated cells: 166.4;Late spermatids: 111.3;Respiratory ciliated cells: 177.8;Spermatocytes: 149.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-87 MG: 16.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA003090, HPA003136, HPA075108" Approved Approved "Nucleoplasm,Plasma membrane,Centriolar satellite" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Plasma membrane" "Centriolar satellite" "HPA003090: AB_1845571, HPA003136: AB_1078330, HPA075108: " "unprognostic (1.84e-2)" "unprognostic (1.31e-1)" "unprognostic (5.71e-2)" "prognostic favorable (6.34e-4)" "unprognostic (1.11e-2)" "unprognostic (1.29e-2)" "unprognostic (1.28e-2)" "unprognostic (2.08e-1)" "unprognostic (1.85e-1)" "unprognostic (4.62e-2)" "unprognostic (1.01e-1)" "unprognostic (3.89e-1)" "unprognostic (1.40e-3)" "unprognostic (6.14e-2)" "unprognostic (2.57e-1)" "unprognostic (7.93e-2)" "unprognostic (6.04e-3)" 4.9 2.8 5.8 2.3 6.3 6.5 7.3 5.5 9.0 6.5 15.9 7.1 2.0 7.1 14.6 5.2 22.5 5.7 4.4 6.3 5.8 9.7 2.2 6.8 1.7 9.7 9.8 5.1 2.8 5.0 10.7 2.4 8.3 5.5 3.5 24.3 3.8 7.1 2.3 3.1 2.4 5.5 8.0 1.4 3.4 38.6 6.2 2.8 13.2 3.3 2.1 5.0 3.1 6.6 5.4 3.1 1.3 8.7 5.7 12.5 1.1 4.6 6.5 4.6 4.3 1.1 3.7 5.3 1.2 5.7 2.0 1.3 1.8 0.8 5.2 0.8 1.0 0.6 3.1 1.2 4.8 2.7 0.3 6.1 4.2 10.3 1.3 7.3 1.7 9.7 2.9 0.9 3.4 4.3 8.5 1.3 0.4 0.5 2.1 3.0 3.4 0.9 7.9 1.4 5.2 3.3 9.0 3.6 2.6 1.3 9.2 0.2 3.8 5.7 4.0 7.6 1.3 1.9 4.9 3.3 16.7 0.3 1.6 1.1 0.0 0.1 1.5 0.0 1.8 0.5 1.4 1.0 0.1 0.6 1.9 1.5 1.0 1.1 0.0 2.4 0.3 1.2 5.8 6.3 5.5 9.0 6.3 5.8 9.7 9.8 8.3 8.0 6.2 6.6 3.8 12.8 8.1 0.0 1.4 0.0 3.8 0.0 4.0 7.8 15.8 8.0 0.0 7.2 30.3 3.7 29.2 1.8 3.9 1.8 15.6 9.0 239.3 166.4 15.1 3.1 2.4 39.6 0.0 3.5 2.6 7.4 2.0 18.2 1.3 4.3 3.6 4.5 2.3 6.7 0.0 2.7 0.0 1.6 0.0 111.3 10.8 3.9 0.0 0.0 0.8 5.7 4.1 0.0 0.0 3.0 0.2 6.0 0.7 2.5 1.0 23.5 177.8 29.9 0.0 4.3 4.0 149.2 14.7 1.3 0.0 1.0 2.3 4.1 0.9 3.4 BBS5 DKFZp762I194 ENSG00000163093 "Bardet-Biedl syndrome 5" Q8N3I7 2 169479480-169506655 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Sensory transduction, Transport, Vision" "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Mental retardation, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 70.9;Early spermatids: 213.4;Endometrial ciliated cells: 49.1;Rod photoreceptor cells: 63.4;Spermatocytes: 62.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SK-MEL-30: 17.3" "Low region specificity" "Detected in all" HPA046125 Uncertain NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA046125: AB_2679549" "unprognostic (4.37e-2)" "unprognostic (5.48e-2)" "unprognostic (2.14e-1)" "unprognostic (1.89e-2)" "unprognostic (1.21e-2)" "unprognostic (4.85e-2)" "unprognostic (1.81e-1)" "unprognostic (5.83e-2)" "unprognostic (2.35e-1)" "unprognostic (2.78e-1)" "prognostic favorable (1.02e-4)" "unprognostic (3.55e-1)" "unprognostic (2.62e-2)" "unprognostic (1.25e-1)" "unprognostic (8.67e-2)" "unprognostic (8.83e-2)" "unprognostic (1.67e-1)" 4.2 5.5 5.9 2.8 6.2 1.4 3.5 4.9 6.0 4.4 9.5 4.4 2.6 4.3 3.8 2.6 7.8 3.1 5.2 6.7 6.3 4.2 2.1 2.9 2.1 6.3 7.1 4.8 3.2 7.2 7.9 2.2 6.2 4.2 1.3 11.3 2.7 4.2 7.1 3.9 2.0 2.9 5.9 2.5 3.3 8.6 6.1 1.5 6.1 3.2 1.0 4.4 2.9 5.3 1.0 2.8 3.2 5.2 8.0 6.4 3.2 7.2 2.3 8.4 3.6 2.0 2.0 0.1 3.3 3.5 5.6 3.1 2.4 1.2 3.2 4.9 0.9 1.8 1.2 4.0 8.0 3.9 4.3 7.1 7.3 5.9 1.5 3.9 2.9 5.0 6.7 0.0 2.5 4.0 6.5 4.0 2.7 0.7 3.6 0.0 0.7 0.0 4.6 3.0 3.0 5.4 4.9 3.7 17.3 1.1 3.7 4.3 2.9 11.8 5.6 9.5 6.6 4.5 6.8 0.1 7.0 2.5 7.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 5.9 6.2 4.9 6.0 6.7 6.3 6.3 7.1 6.2 5.9 6.1 5.3 3.7 0.0 5.1 18.9 0.7 1.3 1.2 1.2 2.8 17.1 3.4 4.2 5.1 1.5 3.5 11.0 70.9 0.8 0.3 0.3 0.0 2.1 213.4 49.1 10.7 2.5 2.4 0.4 38.0 1.5 0.5 4.9 0.5 5.8 0.0 3.2 1.1 0.7 1.4 10.1 34.1 1.7 4.1 4.5 0.4 38.4 5.0 2.0 7.2 14.0 0.1 12.2 0.0 17.6 19.0 1.1 0.5 6.0 1.7 0.7 0.4 2.1 15.1 63.4 0.0 5.5 4.2 62.3 7.8 0.9 1.7 0.3 1.1 7.8 1.0 0.4 BBS7 "BBS2L1, FLJ10715" ENSG00000138686 "Bardet-Biedl syndrome 7" Q8IWZ6 4 121824329-121870487 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Sensory transduction, Transport, Vision" "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Mental retardation, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "retina: 56.6" "Cell type enhanced" "Detected in all" "Excitatory neurons: 65.1;Inhibitory neurons: 58.6;Rod photoreceptor cells: 68.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044592 Approved NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA044592: AB_10795882" "unprognostic (6.36e-2)" "unprognostic (3.11e-3)" "unprognostic (1.37e-2)" "unprognostic (1.85e-1)" "unprognostic (1.10e-2)" "unprognostic (1.89e-1)" "unprognostic (3.15e-5)" "unprognostic (6.66e-3)" "unprognostic (1.44e-1)" "unprognostic (2.48e-1)" "unprognostic (1.49e-1)" "unprognostic (9.10e-3)" "unprognostic (2.67e-2)" "unprognostic (1.62e-1)" "unprognostic (4.22e-2)" "unprognostic (1.41e-1)" "unprognostic (4.33e-1)" 6.9 6.4 7.3 5.3 7.7 2.1 6.1 9.8 12.4 7.9 2.6 6.3 5.0 10.5 4.9 6.2 7.9 5.9 4.7 7.7 6.4 6.7 2.4 5.3 5.0 8.9 7.8 12.4 3.7 9.1 9.1 4.7 8.7 6.8 6.3 56.6 4.8 6.6 3.8 6.8 5.3 10.3 5.1 4.6 4.8 9.1 8.4 6.4 5.5 5.5 4.8 5.8 6.9 8.9 13.7 6.6 14.9 10.9 18.8 27.2 5.4 18.3 14.6 15.5 14.2 5.2 7.4 15.0 5.1 21.7 11.6 7.1 15.5 14.8 17.6 14.4 12.1 8.9 10.0 6.2 16.7 12.7 8.0 14.0 10.6 17.7 13.3 20.2 16.8 10.0 6.0 14.8 22.1 4.3 21.3 6.1 7.9 8.3 8.2 9.7 19.3 4.6 15.7 4.8 16.4 7.0 17.5 7.7 14.0 19.7 6.5 4.7 16.9 11.6 12.5 16.2 11.8 13.9 10.3 13.1 13.4 10.0 11.6 0.6 1.0 1.7 1.9 1.1 1.5 0.9 1.5 1.8 1.2 0.9 1.2 1.6 0.2 2.0 1.2 1.2 1.6 1.0 7.3 7.7 9.8 12.4 7.7 6.4 8.9 7.8 8.7 5.1 8.4 8.9 15.7 6.4 8.4 12.7 6.9 8.7 10.8 13.7 5.7 16.6 6.0 9.3 8.4 4.3 13.0 11.0 47.9 8.5 6.6 6.4 13.7 14.6 22.2 14.4 19.9 11.2 6.1 9.5 65.1 9.8 21.5 14.4 6.1 10.6 15.2 9.2 8.6 5.0 11.4 16.8 58.6 8.2 16.2 6.3 6.1 12.9 13.1 7.7 8.8 16.9 6.3 12.6 5.2 30.7 26.4 15.6 5.1 11.3 5.6 9.3 6.0 15.1 16.5 68.9 19.7 12.2 15.2 39.6 22.4 10.9 8.5 5.7 10.7 11.4 8.4 8.6 BCAR3 "AND-34, NSP2, SH2D3B" ENSG00000137936 "BCAR3 adaptor protein, NSP family member" O75815 1 93561741-93847150 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 72.5;Basal prostatic cells: 149.0;Extravillous trophoblasts: 75.0;Urothelial cells: 106.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.0;memory B-cell: 1.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "hTERT-HME1: 159.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014858 Approved Approved "Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cytosol" Centrosome "HPA014858: AB_1845302" "unprognostic (9.16e-2)" "unprognostic (2.06e-2)" "unprognostic (2.79e-2)" "unprognostic (1.09e-1)" "unprognostic (9.60e-3)" "prognostic unfavorable (8.41e-4)" "prognostic unfavorable (5.42e-4)" "prognostic unfavorable (8.92e-7)" "unprognostic (2.44e-1)" "unprognostic (3.66e-1)" "prognostic unfavorable (4.38e-4)" "unprognostic (1.51e-2)" "prognostic favorable (3.08e-7)" "unprognostic (2.13e-1)" "unprognostic (1.14e-1)" "unprognostic (7.05e-2)" "unprognostic (1.87e-1)" 31.0 10.6 17.7 6.6 20.9 1.0 18.5 19.3 15.3 10.0 21.1 15.3 13.4 5.7 3.6 8.1 9.5 7.5 13.1 14.8 18.7 15.9 11.9 14.2 13.8 21.1 20.6 11.4 4.2 4.0 4.6 17.0 18.9 8.9 16.6 1.5 21.9 9.5 24.4 15.6 12.9 8.0 19.0 4.8 16.2 6.3 21.7 4.3 10.4 21.1 13.0 13.6 9.8 17.8 56.0 23.4 43.5 3.4 18.4 14.4 37.1 56.9 98.3 45.9 28.1 4.0 40.9 9.0 18.9 88.1 59.4 34.0 1.3 73.5 39.7 4.0 1.3 0.0 16.2 10.3 33.1 0.4 0.2 17.3 79.5 47.5 159.7 44.1 51.1 1.1 1.6 0.3 125.7 8.6 1.0 0.2 13.6 24.5 79.7 3.7 62.7 1.3 120.4 70.1 1.5 3.6 27.4 29.1 36.1 16.8 32.9 2.2 60.8 67.3 17.5 29.2 76.0 4.5 2.1 1.2 10.1 0.2 25.2 2.0 0.0 0.0 0.0 0.4 0.0 1.8 0.0 0.0 0.3 1.6 0.0 0.1 0.0 0.0 0.0 0.7 0.1 0.0 17.7 20.9 19.3 15.3 14.8 18.7 21.1 20.6 18.9 19.0 21.7 17.8 26.9 3.2 7.2 72.5 10.2 9.8 149.0 11.3 2.8 0.9 7.9 13.5 7.1 11.5 11.7 14.7 0.0 27.5 2.5 30.8 27.4 11.3 11.3 13.3 2.6 17.9 14.9 0.4 5.2 6.3 75.0 6.3 15.8 16.6 3.8 33.7 5.7 10.3 11.9 21.9 11.2 20.7 8.2 5.3 12.7 12.8 10.2 8.3 19.6 64.6 9.4 4.0 0.0 3.0 2.1 28.0 22.0 1.2 8.9 36.3 25.8 23.7 18.1 0.4 72.3 23.8 19.9 4.2 3.7 4.8 10.2 18.9 3.7 8.3 10.3 106.1 BCAS2 "DAM1, Snt309, SPF27" ENSG00000116752 "BCAS2 pre-mRNA processing factor" O75934 1 114567557-114581629 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 613.4" "Low region specificity" "Detected in all" HPA067881 Supported Supported "Nuclear speckles,Centrosome" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" "Nuclear speckles, Centrosome" "HPA067881: AB_2685915" "unprognostic (6.93e-2)" "unprognostic (1.88e-2)" "unprognostic (8.58e-3)" "unprognostic (4.74e-2)" "unprognostic (2.49e-1)" "unprognostic (2.99e-3)" "prognostic unfavorable (8.23e-7)" "unprognostic (1.16e-1)" "unprognostic (8.51e-3)" "prognostic favorable (7.96e-4)" "unprognostic (1.57e-2)" "prognostic unfavorable (4.27e-4)" "prognostic favorable (6.49e-4)" "unprognostic (2.25e-3)" "unprognostic (1.03e-1)" "prognostic unfavorable (5.24e-4)" "unprognostic (1.87e-1)" 31.9 40.6 32.8 28.0 35.4 76.2 38.2 36.7 45.3 27.1 34.6 31.6 25.5 35.1 49.7 34.1 24.9 31.8 39.3 35.7 38.8 44.6 51.3 26.9 38.5 34.9 37.6 32.5 28.8 41.3 33.1 27.8 37.8 35.6 32.1 40.4 29.6 27.2 56.4 29.8 26.1 27.8 34.7 26.1 28.7 31.8 34.6 32.2 42.4 25.9 36.2 41.5 23.4 37.7 100.0 35.6 70.8 69.9 37.8 43.8 108.8 71.3 57.0 95.6 97.4 50.8 40.6 88.8 93.9 46.9 64.3 47.8 85.5 72.7 133.3 76.7 75.7 45.0 67.2 74.6 68.8 117.8 48.1 39.2 79.4 97.5 121.3 44.2 63.7 95.0 89.6 64.5 80.5 613.4 103.1 87.5 125.6 60.8 80.8 73.9 127.6 62.2 68.1 85.9 93.5 62.2 90.3 70.3 114.3 59.6 62.3 91.0 52.8 58.2 74.7 116.9 138.2 68.5 76.9 143.4 113.4 94.7 223.9 54.4 36.8 65.3 56.0 45.2 78.9 63.3 71.6 70.6 39.7 58.0 73.8 71.9 34.7 75.0 51.0 51.2 77.6 72.8 32.8 35.4 36.7 45.3 35.7 38.8 34.9 37.6 37.8 34.7 34.6 37.7 51.6 28.9 45.4 11.1 110.1 77.9 114.2 155.9 91.0 62.6 36.7 49.1 76.0 27.1 85.4 49.7 37.5 76.6 99.0 26.4 95.9 66.6 30.3 79.0 51.5 46.9 50.0 30.5 16.4 66.8 89.8 60.0 25.0 139.1 99.1 46.0 28.2 31.3 66.9 38.7 15.1 43.1 103.7 34.9 93.3 17.7 39.7 80.8 67.6 12.2 50.6 98.3 55.6 15.1 18.1 51.2 37.9 43.6 176.7 49.8 29.4 103.9 55.6 67.1 39.5 55.5 71.4 80.8 40.6 95.7 63.4 101.2 117.4 64.2 36.0 114.2 BCL11B "CTIP-2, CTIP2, hRIT1-alpha, ZNF856B" ENSG00000127152 "BAF chromatin remodeling complex subunit BCL11B" Q9C0K0 14 99169287-99272197 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Repressor "Cancer-related genes, Disease variant, Mental retardation, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 21.2;lymphoid tissue: 36.6;skin 1: 15.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 62.8;Basal squamous epithelial cells: 73.4;Excitatory neurons: 57.5;Inhibitory neurons: 105.7;NK-cells: 51.5;Suprabasal keratinocytes: 71.3;T-cells: 133.4" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "amygdala: 8.0;basal ganglia: 21.2;cerebral cortex: 17.2;hippocampal formation: 18.9" "Group enriched" "Detected in many" 8 "gdT-cell: 2.0;MAIT T-cell: 1.8;memory CD4 T-cell: 2.8;memory CD8 T-cell: 2.4;naive CD4 T-cell: 4.6;naive CD8 T-cell: 3.1;T-reg: 2.0" "Lineage enriched" "Detected in single" 14 "T-cells: 4.6" "Group enriched" "Detected in some" 6 "JURKAT: 38.3;MOLT-4: 47.3" "Region enhanced" "Detected in many" "basal ganglia: 64.3" "Region enhanced" "Detected in many" "basal ganglia: 30.0" HPA049117 Enhanced Supported Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "Nucleoli fibrillar center" "HPA049117: AB_2680639" "unprognostic (1.64e-5)" "unprognostic (4.66e-2)" "unprognostic (2.35e-2)" "unprognostic (1.87e-2)" "unprognostic (9.37e-2)" "unprognostic (5.97e-2)" "unprognostic (4.75e-2)" "unprognostic (6.07e-2)" "unprognostic (1.74e-1)" "unprognostic (1.40e-2)" "unprognostic (1.90e-1)" "unprognostic (1.12e-1)" "unprognostic (1.60e-6)" "unprognostic (1.07e-3)" "unprognostic (1.61e-1)" "unprognostic (3.31e-3)" "prognostic favorable (7.48e-4)" 0.4 0.3 8.0 5.1 21.2 4.9 1.1 0.0 17.2 0.9 0.0 1.2 2.0 0.2 0.5 4.3 0.3 0.9 0.1 18.9 1.1 0.3 0.4 1.1 10.2 0.3 0.8 0.2 0.1 0.0 0.2 0.1 0.0 0.5 1.4 0.0 1.7 0.3 0.2 15.0 3.5 0.2 1.5 4.4 1.9 0.5 2.0 36.6 0.8 0.0 7.5 1.3 2.9 3.9 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.4 1.7 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.9 0.0 0.2 0.0 0.0 38.3 0.0 4.1 0.0 2.8 47.3 0.8 0.5 3.6 0.0 7.0 0.0 0.0 0.0 2.6 3.7 0.0 0.2 0.0 0.0 0.3 0.0 0.1 0.0 0.0 1.7 0.2 0.0 2.6 0.1 0.0 2.0 0.7 0.0 0.0 0.0 0.1 2.0 0.0 1.8 0.0 2.8 2.4 0.0 0.0 4.6 3.1 0.0 0.3 0.0 0.0 2.0 0.8 8.0 21.2 0.0 17.2 18.9 1.1 0.3 0.8 0.0 1.5 2.0 3.9 1.3 3.2 0.0 1.3 6.4 62.8 1.6 6.3 73.4 0.4 4.3 4.4 3.8 4.3 1.3 0.0 0.0 0.1 44.2 3.8 1.9 0.2 0.2 0.2 0.2 1.2 1.2 5.3 57.5 0.5 0.0 3.3 2.0 0.3 5.1 0.2 3.3 0.3 0.3 0.0 105.7 4.9 2.0 1.0 11.4 0.4 0.6 4.0 5.4 1.0 4.9 0.0 51.5 32.2 2.0 1.1 5.4 0.0 24.4 0.6 10.1 0.5 0.3 0.1 0.0 0.5 1.9 1.6 5.8 42.7 71.3 0.0 133.4 0.1 9.7 0.6 BCL2L1 "Bcl-X, bcl-xL, bcl-xS, BCL2L, BCLX, PPP1R52" ENSG00000171552 "BCL2 like 1" Q07817 20 31664452-31723989 "Cancer-related genes, Predicted membrane proteins, RAS pathway related proteins, Transporters" "Apoptosis, Endocytosis" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 160.0;Pancreatic endocrine cells: 187.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035734, CAB072801" Approved Approved Mitochondria NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 39: CACO-2 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" Mitochondria "CAB072801: , HPA035734: AB_2674757" "unprognostic (2.29e-1)" "unprognostic (5.40e-3)" "unprognostic (1.78e-2)" "prognostic unfavorable (9.10e-4)" "unprognostic (1.37e-1)" "unprognostic (1.09e-1)" "unprognostic (5.04e-2)" "unprognostic (7.82e-3)" "prognostic favorable (9.57e-4)" "unprognostic (1.67e-1)" "prognostic unfavorable (5.87e-4)" "unprognostic (1.06e-1)" "prognostic favorable (8.89e-5)" "unprognostic (9.67e-2)" "unprognostic (3.03e-2)" "unprognostic (2.02e-2)" "unprognostic (3.32e-2)" 80.3 46.9 46.3 26.1 53.7 99.0 71.0 46.7 54.5 46.5 88.2 42.4 49.4 39.2 11.9 77.8 42.7 51.7 77.9 42.2 48.2 95.7 85.2 95.1 25.8 49.5 49.4 23.1 54.7 30.4 49.8 42.0 51.1 52.0 26.2 41.0 70.6 25.2 55.4 65.7 48.9 25.0 41.3 53.4 66.6 46.2 54.4 111.5 51.4 38.8 28.9 42.8 54.7 59.7 327.0 188.4 30.7 32.4 167.8 123.1 101.0 73.8 113.2 69.6 66.4 429.2 150.9 48.2 176.7 108.4 140.7 105.8 42.9 216.7 46.2 55.1 8.6 231.3 34.4 231.6 123.0 19.6 137.7 90.7 77.4 89.4 194.0 102.4 106.0 81.6 150.0 34.5 238.7 94.3 73.9 20.6 45.4 150.8 153.2 43.5 92.9 164.3 249.3 83.4 85.4 38.4 89.3 92.6 42.4 57.2 180.5 26.3 154.1 90.0 109.1 36.8 139.4 22.7 150.7 37.9 143.5 99.5 59.5 28.6 11.0 25.6 39.9 11.7 30.9 4.8 17.1 26.8 10.4 6.0 7.7 18.6 12.5 19.8 13.4 7.0 21.8 28.2 46.3 53.7 46.7 54.5 42.2 48.2 49.5 49.4 51.1 41.3 54.4 59.7 41.6 16.0 9.2 22.5 10.1 18.4 70.2 40.8 26.7 21.9 25.5 15.4 9.7 91.5 36.3 38.6 45.9 27.1 13.7 41.7 86.1 92.2 10.2 71.4 14.6 35.8 24.7 160.0 21.8 65.9 11.3 15.5 37.2 58.2 12.7 10.6 36.4 40.8 38.2 28.6 19.5 26.0 69.2 22.1 13.3 4.6 19.0 27.6 17.8 49.6 76.9 24.1 54.6 13.6 55.6 187.7 22.4 42.9 38.0 102.9 54.6 76.5 76.4 33.7 46.0 14.9 42.7 31.0 15.1 13.6 9.8 18.9 24.9 13.6 19.6 143.0 BCL2L2 "BCL-W, KIAA0271, PPP1R51" ENSG00000129473 "BCL2 like 2" Q92843 14 23298790-23311751 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Apoptosis "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB040539, HPA048740" Approved Uncertain Nucleoplasm NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 45: Intestine - Brush border" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "CAB040539: , HPA048740: " "unprognostic (8.23e-3)" "unprognostic (9.85e-2)" "unprognostic (1.71e-2)" "unprognostic (6.08e-2)" "unprognostic (2.04e-1)" "unprognostic (1.64e-1)" "unprognostic (3.47e-3)" "unprognostic (1.53e-2)" "unprognostic (1.78e-1)" "unprognostic (2.91e-3)" "unprognostic (1.50e-3)" "unprognostic (2.60e-1)" "prognostic favorable (1.99e-6)" "unprognostic (2.44e-1)" "unprognostic (2.00e-1)" "unprognostic (6.60e-2)" "unprognostic (5.38e-2)" 48.5 36.6 102.4 26.0 95.3 13.9 35.6 83.7 112.4 30.2 61.8 86.9 28.5 43.0 30.5 46.8 35.4 24.7 37.3 89.8 88.8 35.0 20.9 34.6 13.9 94.8 94.0 31.8 53.3 52.9 38.1 23.8 91.7 47.4 31.8 51.9 52.2 45.5 24.2 46.5 34.3 41.5 101.0 20.5 54.2 25.1 108.3 10.7 38.5 19.9 16.4 55.6 34.9 92.4 24.1 23.0 25.6 19.0 43.4 39.2 19.3 43.9 28.5 21.8 24.9 16.3 42.6 16.8 14.2 26.6 27.4 43.9 15.9 28.1 29.4 8.9 12.7 18.4 44.4 30.3 26.6 20.7 30.0 30.3 54.0 17.6 27.1 30.6 18.6 2.9 17.3 18.0 27.8 17.8 1.6 14.5 8.0 33.4 41.3 12.8 28.1 8.2 19.7 45.5 31.7 18.0 20.8 31.3 31.2 15.6 20.6 15.5 37.1 35.1 24.8 27.6 23.1 22.0 12.7 2.2 21.6 16.0 43.5 0.0 0.4 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.3 102.4 95.3 83.7 112.4 89.8 88.8 94.8 94.0 91.7 101.0 108.3 92.4 9.2 9.6 13.1 0.0 2.6 8.7 9.5 12.7 5.7 20.0 11.0 8.0 28.9 4.3 13.6 5.5 25.0 5.3 3.5 16.8 13.7 8.0 20.1 11.1 10.4 10.8 18.6 2.1 0.0 18.3 4.0 10.4 9.7 12.1 5.7 12.0 11.4 7.2 5.5 20.2 0.0 16.8 6.1 8.4 4.0 6.1 11.1 5.5 7.2 0.0 7.5 7.4 2.1 0.0 0.0 25.5 11.0 21.4 4.5 17.2 16.3 9.2 12.2 12.7 6.6 12.6 15.5 0.5 0.9 10.8 11.1 5.6 1.5 8.9 10.5 17.6 BCL6 "BCL5, BCL6A, LAZ3, ZBTB27, ZNF51" ENSG00000113916 "BCL6 transcription repressor" P41182 3 187721377-187745725 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Immunity, Inflammatory response, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 485.9" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 205.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "neutrophil: 269.1;non-classical monocyte: 76.4" "Group enriched" "Detected in all" 7 "granulocytes: 269.1;monocytes: 76.4" "Cell line enhanced" "Detected in many" "Daudi: 166.4;HSkMC: 113.9;U-698: 231.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000307, HPA004899, HPA050645" Enhanced Supported Nucleoplasm NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "CAB000307: AB_2063451, HPA004899: AB_1078273, HPA050645: AB_2681199" "unprognostic (5.36e-2)" "unprognostic (3.29e-2)" "unprognostic (1.63e-3)" "unprognostic (2.49e-1)" "unprognostic (2.85e-1)" "unprognostic (6.34e-3)" "unprognostic (2.62e-2)" "unprognostic (3.33e-3)" "unprognostic (8.75e-2)" "unprognostic (2.04e-2)" "unprognostic (1.63e-3)" "unprognostic (1.29e-1)" "prognostic unfavorable (1.27e-9)" "unprognostic (5.22e-2)" "unprognostic (7.82e-2)" "unprognostic (5.67e-2)" "unprognostic (2.58e-2)" 143.0 49.4 54.3 53.9 53.4 123.7 126.9 85.9 57.9 100.0 35.0 87.1 7.5 68.1 16.4 44.6 140.7 45.6 72.1 50.9 68.7 37.0 65.3 110.5 56.0 104.1 69.4 65.6 49.2 11.3 44.8 15.3 74.2 57.5 10.3 34.2 70.3 22.2 485.9 160.7 34.4 43.0 55.9 106.3 58.4 18.6 69.0 43.2 50.4 96.6 47.7 90.6 81.5 64.1 5.1 13.8 14.4 3.2 98.1 78.0 14.9 16.5 39.2 18.4 19.4 9.4 7.6 166.4 11.5 21.0 11.7 7.7 4.4 10.6 15.3 33.8 5.1 0.2 6.7 22.5 51.5 2.1 0.9 113.9 68.8 22.7 32.9 60.1 10.2 4.2 1.6 27.6 18.2 5.7 5.5 1.3 1.4 3.0 10.3 45.4 7.0 0.8 13.6 23.2 3.1 0.2 18.8 8.1 11.0 30.2 35.3 5.9 21.2 43.7 7.1 16.6 7.5 21.2 7.2 231.6 24.2 6.0 31.7 8.8 33.0 18.9 5.5 37.3 5.4 6.6 3.4 5.0 24.6 15.3 2.1 2.3 269.1 3.9 76.4 4.0 3.1 30.7 54.3 53.4 85.9 57.9 50.9 68.7 104.1 69.4 74.2 55.9 69.0 64.1 35.7 19.2 67.4 66.0 22.7 47.3 14.7 18.8 205.5 10.9 55.3 54.6 71.4 14.3 28.9 16.5 20.9 1.4 36.0 3.5 0.0 12.2 13.3 36.2 26.7 25.0 4.8 3.2 7.6 12.5 2.7 57.3 12.2 51.4 11.4 9.4 15.0 51.2 11.9 0.0 19.6 2.3 16.2 67.5 74.4 8.6 28.9 48.1 35.6 7.5 16.8 39.1 1.0 50.8 7.8 7.9 0.3 18.8 14.2 27.9 1.2 1.5 29.5 9.7 32.9 77.0 84.9 0.4 1.2 72.4 61.5 4.1 30.0 10.3 2.8 29.7 BCR "ALL, BCR1, CML, D22S11, D22S662, PHL" ENSG00000186716 "BCR activator of RhoGEF and GTPase" P11274 22 23179704-23318037 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "GTPase activation, Guanine-nucleotide releasing factor, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 65.7" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 70.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "K-562: 112.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010421, CAB018545, HPA038337" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 65: Brain - Ion transport" "Cluster 1: K-562 - Erythropoiesis" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cytosol" Nucleoplasm "CAB010421: AB_2274682, CAB018545: AB_2063918, HPA038337: AB_10675795" "unprognostic (7.46e-3)" "unprognostic (2.43e-2)" "unprognostic (2.15e-3)" "unprognostic (1.16e-1)" "unprognostic (5.35e-2)" "unprognostic (1.45e-1)" "unprognostic (5.08e-2)" "unprognostic (1.44e-1)" "unprognostic (7.55e-2)" "unprognostic (1.81e-1)" "unprognostic (9.46e-2)" "unprognostic (2.39e-2)" "prognostic favorable (9.15e-10)" "unprognostic (1.47e-1)" "unprognostic (7.10e-2)" "unprognostic (4.10e-2)" "unprognostic (7.43e-2)" 19.4 11.1 34.3 11.0 65.7 34.6 17.4 15.9 30.7 14.3 10.6 11.7 10.0 12.3 16.1 24.5 12.1 9.3 12.2 45.0 22.2 21.1 13.8 18.6 13.7 27.1 26.5 9.4 14.6 20.6 25.0 10.3 24.1 11.8 7.6 7.4 18.3 10.1 5.8 23.5 10.2 8.8 20.9 11.4 16.1 11.0 35.0 14.7 19.7 5.7 10.8 15.3 14.3 14.1 47.6 20.1 30.3 31.2 17.7 12.1 45.6 16.8 15.7 15.2 12.2 35.6 18.7 32.9 30.5 14.4 14.7 47.6 3.6 46.8 4.3 63.3 32.3 28.8 27.7 28.6 22.9 26.9 14.6 10.2 31.1 22.8 19.8 27.0 53.6 23.3 112.5 15.1 7.0 31.3 25.4 21.4 25.8 37.4 19.5 32.9 12.4 21.7 23.7 29.6 27.7 26.3 30.7 26.1 12.6 19.3 16.6 21.7 61.4 9.1 1.0 14.9 14.0 3.4 14.8 11.7 23.4 20.1 14.3 0.0 0.5 0.0 3.1 0.2 1.1 0.6 1.5 1.6 0.4 0.6 1.3 1.7 0.5 1.5 0.5 0.4 0.8 1.4 34.3 65.7 15.9 30.7 45.0 22.2 27.1 26.5 24.1 20.9 35.0 14.1 19.3 9.6 11.5 51.2 4.5 15.4 11.9 18.2 6.2 22.9 17.1 9.9 7.5 17.2 20.9 18.4 22.9 14.0 23.9 17.7 9.8 14.4 5.6 22.1 8.0 27.8 19.9 5.5 24.6 16.6 6.8 7.1 11.7 31.4 10.8 9.9 70.6 22.1 7.2 23.5 20.7 13.9 12.2 9.3 11.1 13.5 8.7 9.2 5.4 18.7 6.6 13.2 15.5 32.2 7.0 27.7 8.1 5.7 10.7 11.8 10.7 18.2 12.5 9.4 0.0 4.0 6.8 2.7 7.3 9.3 15.8 10.8 10.3 10.0 13.7 13.3 BDNF ENSG00000176697 "Brain derived neurotrophic factor" P23560 11 27654893-27722058 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 38.5;Bipolar cells: 13.8;Cardiomyocytes: 9.1;Excitatory neurons: 22.3;Smooth muscle cells: 25.8;Theca cells: 9.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 36.6;BJ hTERT+ SV40 Large T+: 28.0;BJ hTERT+ SV40 Large T+ RasG12V: 20.9;HBF TERT88: 26.5;U-138 MG: 37.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB009564, HPA031440, HPA056104" Enhanced Supported "Nuclear speckles,Mitochondria" "Secreted to blood" NA Yes 16000000 24000 "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles, Mitochondria" "CAB009564: AB_2064213, HPA031440: AB_2673883, HPA056104: AB_2683038" "unprognostic (1.25e-2)" "unprognostic (2.84e-1)" "unprognostic (4.35e-2)" "unprognostic (2.54e-2)" "unprognostic (1.01e-2)" "unprognostic (6.82e-2)" "unprognostic (2.39e-2)" "unprognostic (2.21e-1)" "unprognostic (3.20e-1)" "unprognostic (1.78e-1)" "unprognostic (1.22e-2)" "unprognostic (2.65e-1)" "unprognostic (3.22e-2)" "unprognostic (3.88e-2)" "unprognostic (5.88e-2)" "unprognostic (1.40e-1)" "unprognostic (2.84e-3)" 0.4 0.5 1.9 0.2 2.4 0.2 0.2 3.3 5.3 0.6 0.1 0.4 0.3 0.2 3.3 0.6 0.1 0.7 3.6 8.2 1.9 0.6 0.1 2.0 0.1 3.3 2.1 0.5 0.4 0.0 1.2 1.6 2.5 2.0 0.1 0.7 0.3 1.8 0.4 0.9 0.1 0.1 0.4 0.1 0.3 0.6 1.6 0.3 1.0 0.0 0.1 2.1 0.6 0.8 2.9 12.2 0.3 0.0 3.7 2.2 0.0 36.6 7.9 28.0 20.9 0.1 4.0 0.0 3.7 11.8 0.5 1.4 0.1 0.2 26.5 0.2 0.1 0.0 3.5 0.0 17.4 0.2 0.2 9.2 4.2 6.8 3.7 18.1 1.3 0.1 0.0 0.1 4.8 0.0 0.0 0.0 4.0 0.1 2.9 0.0 2.0 0.0 4.5 0.0 0.2 1.1 7.8 0.1 0.1 1.7 0.2 0.0 11.0 37.6 6.9 14.4 9.2 0.5 0.1 0.0 14.1 1.3 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 2.4 3.3 5.3 8.2 1.9 3.3 2.1 2.5 0.4 1.6 0.8 0.2 38.5 0.5 1.6 0.0 0.6 0.4 0.5 1.8 13.8 0.5 0.9 9.1 0.0 0.4 1.8 4.2 0.4 0.0 0.1 0.0 0.8 1.8 0.3 0.3 0.2 0.0 0.0 22.3 0.0 0.5 6.1 0.0 0.1 1.3 1.9 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.4 1.5 0.3 0.9 1.8 0.0 0.0 0.2 0.0 2.0 2.2 0.2 0.0 0.0 0.0 0.8 0.0 1.5 0.1 1.8 0.0 1.8 25.8 3.7 0.8 2.3 0.0 0.7 0.0 9.3 0.1 0.1 BEND2 "CXorf20, MGC33653" ENSG00000177324 "BEN domain containing 2" Q8NDZ0 X 18162931-18220886 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 17 "testis: 5.3" "Cell type enhanced" "Detected in some" "Leydig cells: 18.6;Peritubular cells: 13.2;Spermatocytes: 84.5;Spermatogonia: 29.0" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 4 "basophil: 2.9" "Lineage enriched" "Detected in single" 15 "granulocytes: 2.9" "Not detected" "Not detected" "HPA009420, HPA013142" Enhanced NA NA "Cluster 34: Basophils - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA009420: AB_2064489, HPA013142: AB_2668784" "unprognostic (2.23e-2)" "unprognostic (1.17e-1)" 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.1 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 5.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.7 0.1 0.0 0.1 0.0 1.8 0.1 0.1 0.1 0.3 0.1 0.1 0.1 0.2 0.2 0.0 0.2 0.2 0.0 0.0 1.3 0.0 0.3 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.7 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.2 18.6 5.7 0.0 0.0 0.7 0.0 1.0 0.0 0.1 0.0 0.0 13.2 0.0 0.6 0.0 0.0 0.7 0.0 6.6 0.3 0.2 84.5 29.0 0.0 0.4 0.0 0.1 0.0 0.0 0.4 BEND4 "CCDC4, FLJ35632, FLJ43965" ENSG00000188848 "BEN domain containing 4" Q6ZU67 4 42110853-42152878 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.6;prostate: 3.3;testis: 9.4" "Cell type enhanced" "Detected in some" "B-cells: 8.1;Inhibitory neurons: 6.2;Muller glia cells: 10.7;Spermatogonia: 38.3" "Group enriched" "Detected in some" 43 "prostate cancer: 6.3;testis cancer: 5.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 33.2;HEK 293: 7.9;HEL: 21.1;MOLT-4: 13.1;SuSa: 15.4;U-698: 13.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA036850 Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 78: Testis - Spermatogenesis" "Cluster 36: HEL - Hemostasis" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "HPA036850: AB_10600787" "unprognostic (3.62e-4)" "unprognostic (3.82e-1)" "unprognostic (4.82e-2)" "unprognostic (5.96e-3)" "unprognostic (2.97e-3)" "unprognostic (1.10e-1)" "unprognostic (3.81e-2)" "unprognostic (4.00e-1)" "unprognostic (2.97e-1)" "unprognostic (5.58e-2)" "unprognostic (6.71e-3)" "unprognostic (1.68e-1)" "unprognostic (1.54e-5)" "unprognostic (3.48e-1)" "unprognostic (1.49e-1)" "unprognostic (4.58e-3)" "unprognostic (4.24e-1)" 0.0 0.0 0.7 1.1 0.7 0.8 0.0 0.0 1.3 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.1 0.0 1.3 1.1 0.0 0.1 0.2 2.1 1.2 3.6 0.1 0.0 0.0 1.0 0.3 2.8 3.3 0.2 1.1 0.0 0.0 0.0 0.0 1.2 0.1 0.1 1.2 0.2 9.4 0.7 1.1 0.0 0.0 1.6 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.6 0.0 33.2 0.0 0.0 0.0 7.9 21.1 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.4 0.0 7.0 0.0 0.1 0.0 0.0 13.1 0.0 6.2 0.0 1.9 0.0 0.0 0.0 0.0 0.0 4.7 0.8 0.0 0.0 0.0 15.4 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.2 13.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.7 0.0 1.3 1.3 1.1 1.2 3.6 2.8 0.1 0.7 0.4 0.4 0.0 0.0 0.0 8.1 0.0 0.1 0.0 0.0 1.2 0.1 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.6 0.0 3.4 4.4 0.0 0.0 0.3 0.0 0.0 0.0 4.8 2.5 0.0 0.0 3.3 6.2 0.0 0.0 0.0 0.0 1.5 0.0 0.3 0.0 0.0 0.1 10.7 0.0 3.5 0.2 0.0 0.0 0.0 3.9 1.7 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.6 38.3 0.0 0.0 0.0 1.5 2.2 0.0 0.0 BEX2 DJ79P11.1 ENSG00000133134 "Brain expressed X-linked 2" Q9BXY8 X 103309346-103311007 "Predicted intracellular proteins" "Apoptosis, Cell cycle" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pituitary gland: 194.6" "Cell type enhanced" "Detected in many" "Distal tubular cells: 418.7;Muller glia cells: 285.9;Proximal tubular cells: 201.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 52.7;NK-cells: 62.0;T-cells: 68.6" "Cell line enhanced" "Detected in many" "hTCEpi: 94.7;NTERA-2: 91.4;SCLC-21H: 135.2;SH-SY5Y: 61.4" "HPA045384, HPA078630" Uncertain Uncertain Cytosol NA NA "Cluster 30: Non-specific - Translation" "Cluster 68: Epididymis - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "HPA045384: AB_2679305, HPA078630: " "unprognostic (7.56e-2)" "unprognostic (7.08e-2)" "unprognostic (3.46e-2)" "prognostic unfavorable (8.54e-7)" "unprognostic (3.21e-1)" "unprognostic (1.65e-1)" "unprognostic (4.27e-2)" "prognostic favorable (1.52e-4)" "unprognostic (7.36e-3)" "unprognostic (6.82e-2)" "unprognostic (8.22e-3)" "unprognostic (6.63e-2)" "prognostic favorable (3.05e-13)" "unprognostic (4.14e-3)" "unprognostic (6.80e-2)" "unprognostic (1.40e-1)" "unprognostic (2.38e-3)" 5.8 73.6 133.5 6.8 134.9 13.7 19.4 119.0 167.3 16.4 98.2 10.2 3.4 27.6 123.8 9.9 15.5 7.6 29.5 134.4 153.2 58.7 2.5 12.7 14.2 120.7 125.6 62.8 35.5 123.1 194.6 8.0 123.7 24.2 6.0 83.5 26.7 21.0 9.1 17.1 14.0 8.7 117.7 18.5 16.7 43.1 138.6 21.0 103.3 11.5 16.9 8.7 10.7 132.2 0.0 2.8 11.3 0.1 0.2 0.0 45.5 0.3 6.1 7.7 11.3 8.4 3.8 0.0 31.6 0.0 55.4 2.0 0.1 9.4 6.6 0.1 25.4 1.4 1.4 0.4 46.0 0.1 25.4 2.8 94.7 3.7 29.1 17.8 0.5 33.6 17.4 0.7 1.0 4.2 20.1 0.2 91.4 0.0 8.4 0.1 0.0 0.2 3.8 3.7 135.2 61.4 5.9 1.4 22.2 10.7 11.2 0.1 0.0 0.1 9.0 0.3 2.1 30.8 21.6 0.1 15.3 0.0 1.3 13.4 0.4 1.1 21.8 0.4 31.0 52.7 43.8 25.7 1.6 42.3 68.6 50.0 1.4 62.0 0.1 10.0 33.7 18.4 133.5 134.9 119.0 167.3 134.4 153.2 120.7 125.6 123.7 117.7 138.6 132.2 3.7 16.0 68.5 15.0 41.6 31.6 95.6 17.4 100.7 184.7 65.8 145.5 27.0 60.1 43.4 114.0 43.8 72.2 20.9 5.0 418.7 47.5 17.9 11.6 3.3 13.7 100.5 9.4 56.7 42.7 19.9 13.1 23.0 17.0 12.7 87.6 3.6 0.9 7.0 121.1 53.0 29.6 16.2 0.3 5.3 69.4 15.8 4.6 26.6 7.5 2.5 285.9 27.8 35.2 25.8 19.8 8.4 22.2 16.5 64.5 3.7 201.3 9.0 120.5 6.6 32.0 11.4 16.8 5.8 25.7 26.7 63.8 30.2 22.3 22.3 51.1 BEX5 NGFRAP1L1 ENSG00000184515 "Brain expressed X-linked 5" Q5H9J7 X 102153708-102155977 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 124.0;pituitary gland: 77.5" "Cell type enhanced" "Detected in many" "Cholangiocytes: 171.6;Distal tubular cells: 137.0" "Group enriched" "Detected in all" 4 "endometrial cancer: 45.7;thyroid cancer: 14.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 6.2;MAIT T-cell: 15.5;memory CD4 T-cell: 11.6;memory CD8 T-cell: 8.1;naive CD4 T-cell: 16.4;naive CD8 T-cell: 10.1;NK-cell: 10.1;T-reg: 11.9" "Group enriched" "Detected in many" 6 "NK-cells: 10.1;T-cells: 16.4" "Group enriched" "Detected in some" 4 "HAP1: 16.4;Karpas-707: 61.9" "Low region specificity" "Detected in all" HPA059058 Enhanced NA NA "Cluster 32: T-cells - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 2: Karpas-707 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" "HPA059058: AB_2683894" "unprognostic (1.88e-2)" "unprognostic (3.35e-1)" "unprognostic (1.07e-1)" "unprognostic (2.63e-3)" "unprognostic (5.03e-2)" "unprognostic (1.94e-1)" "unprognostic (5.25e-2)" "prognostic favorable (3.09e-4)" "unprognostic (1.23e-1)" "unprognostic (2.83e-2)" "unprognostic (4.97e-3)" "unprognostic (4.63e-2)" "prognostic favorable (1.97e-4)" "unprognostic (3.79e-1)" "unprognostic (8.96e-2)" "unprognostic (3.26e-2)" "unprognostic (2.48e-2)" 3.2 15.6 73.5 3.7 73.2 2.1 7.7 56.0 124.0 4.3 45.0 5.1 4.0 6.3 33.3 1.9 5.0 13.0 5.6 73.4 116.1 20.4 3.5 13.6 4.9 73.0 72.1 13.7 26.3 33.7 77.5 0.0 79.7 6.6 6.1 30.8 7.6 3.7 0.5 3.4 3.3 3.4 59.5 4.4 8.2 13.1 84.0 1.1 25.8 0.5 7.8 2.1 3.4 75.2 0.0 0.0 0.0 0.0 0.6 0.0 2.3 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.9 0.0 0.3 1.4 16.4 0.3 0.0 0.0 0.8 5.5 0.0 0.0 0.1 0.0 2.5 0.0 0.2 0.0 2.4 0.4 0.1 6.0 2.5 61.9 0.3 7.1 0.4 0.1 7.3 0.0 2.6 0.0 0.0 0.2 5.8 0.0 8.9 0.9 0.1 0.1 0.0 1.2 1.6 0.0 6.0 0.4 4.2 0.5 0.0 7.1 4.3 0.0 0.8 0.0 0.0 0.0 0.0 0.0 6.2 0.0 15.5 2.1 11.6 8.1 0.1 0.9 16.4 10.1 0.0 10.1 0.0 0.8 11.9 2.9 73.5 73.2 56.0 124.0 73.4 116.1 73.0 72.1 79.7 59.5 84.0 75.2 9.0 3.2 5.6 4.2 12.2 14.9 24.2 0.1 10.2 53.2 25.9 32.1 19.4 171.6 7.4 38.6 0.0 0.0 13.4 2.1 137.0 16.5 1.3 6.7 0.7 16.3 35.9 1.7 18.1 22.8 0.1 5.8 2.6 8.4 22.8 25.1 26.7 18.2 0.3 57.2 14.0 31.9 0.0 0.8 6.2 7.0 2.5 1.3 30.2 6.5 6.0 55.5 7.2 6.6 3.5 8.5 2.5 0.4 24.5 16.4 0.5 23.2 6.8 25.4 0.0 8.8 2.3 2.1 1.2 4.3 11.2 0.0 13.4 21.5 6.2 11.0 BIRC5 "API4, EPR-1, survivin" ENSG00000089685 "Baculoviral IAP repeat containing 5" O15392 17 78214186-78225636 "Cancer-related genes, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Chromosome partition, Mitosis, Transcription, Transcription regulation" "Protease inhibitor, Repressor, Thiol protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 37.9;lymphoid tissue: 41.0;testis: 19.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 74.7;Early spermatids: 94.1;Erythroid cells: 166.7;Extravillous trophoblasts: 162.0;Spermatocytes: 191.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "T-reg: 14.1" "Lineage enriched" "Detected in many" 6 "T-cells: 14.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA002830, CAB004270" Enhanced Supported "Cytokinetic bridge" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Cytokinetic bridge" "CAB004270: AB_628302, HPA002830: AB_1857672" "unprognostic (8.04e-2)" "unprognostic (3.51e-2)" "unprognostic (4.48e-3)" "unprognostic (2.72e-3)" "unprognostic (3.37e-1)" "unprognostic (3.84e-2)" "prognostic unfavorable (5.28e-6)" "prognostic unfavorable (4.49e-4)" "unprognostic (3.56e-3)" "unprognostic (4.53e-3)" "unprognostic (2.87e-3)" "unprognostic (6.67e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.77e-2)" "unprognostic (4.70e-2)" "unprognostic (1.59e-1)" "unprognostic (1.16e-1)" 0.9 1.1 0.3 8.5 0.5 37.9 5.1 0.6 0.6 1.9 0.4 6.7 7.9 1.6 0.0 12.8 0.6 1.1 0.5 0.4 0.4 0.7 2.1 1.9 16.2 0.6 0.6 0.4 0.6 0.2 0.2 6.1 0.5 0.6 8.0 0.1 1.8 0.2 1.1 5.8 7.6 4.3 0.4 5.8 3.7 19.6 1.0 41.0 0.4 0.1 16.3 2.6 3.2 0.8 139.1 126.2 111.3 121.5 6.7 11.3 41.0 103.6 57.5 144.0 94.2 104.0 52.9 140.7 41.5 60.5 108.7 71.9 113.6 66.6 125.2 48.2 157.5 93.2 71.4 123.1 0.8 90.8 67.0 3.9 4.5 79.8 59.2 21.0 103.5 104.3 118.8 116.0 112.6 79.7 195.5 86.2 83.4 96.3 218.0 100.5 180.2 108.4 34.5 50.2 136.8 94.8 80.3 88.6 71.7 54.1 117.5 84.8 39.5 173.1 152.6 76.0 150.4 83.3 72.2 163.3 63.3 37.8 154.4 0.0 0.0 0.0 0.7 0.0 0.1 2.4 4.1 2.8 0.8 0.2 0.0 0.4 0.5 2.4 0.0 0.2 14.1 3.1 0.3 0.5 0.6 0.6 0.4 0.4 0.6 0.6 0.5 0.4 1.0 0.8 1.2 0.0 20.0 0.0 15.9 8.2 3.7 12.2 2.8 0.7 7.7 8.6 2.3 2.8 10.8 0.0 0.0 74.7 3.3 10.7 0.0 2.0 94.1 5.4 5.1 8.8 3.0 166.7 0.4 0.0 162.0 15.1 8.6 6.9 9.5 42.7 12.8 2.7 52.1 0.0 0.2 17.1 10.2 13.7 13.8 68.4 3.1 9.6 1.8 0.0 0.6 0.4 7.2 0.0 0.3 0.4 2.5 0.7 50.2 2.8 3.2 0.1 2.6 0.5 6.6 0.9 15.2 191.1 58.2 31.3 6.5 19.2 10.1 3.4 38.8 6.3 BLOC1S3 "BLOS3, HPS8" ENSG00000189114 "Biogenesis of lysosomal organelles complex 1 subunit 3" Q6QNY0 19 45178784-45216933 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Albinism, Hermansky-Pudlak syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 39.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050111, HPA070609" Approved Approved "Golgi apparatus" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 34: Spermatids - Unknown function" "Golgi apparatus" "HPA050111: AB_2681019, HPA070609: " "unprognostic (1.17e-1)" "unprognostic (3.97e-2)" "unprognostic (6.94e-3)" "unprognostic (6.26e-2)" "unprognostic (3.14e-1)" "unprognostic (3.04e-2)" "unprognostic (1.75e-2)" "unprognostic (2.30e-2)" "unprognostic (2.01e-1)" "unprognostic (9.49e-2)" "unprognostic (6.39e-2)" "unprognostic (1.68e-1)" "prognostic unfavorable (3.89e-9)" "unprognostic (1.92e-2)" "unprognostic (1.93e-1)" "unprognostic (3.29e-1)" "prognostic favorable (6.86e-4)" 6.7 6.3 7.8 5.9 7.8 12.4 5.7 7.0 8.2 5.7 4.4 5.7 5.3 5.6 5.9 6.4 4.7 3.2 5.2 7.5 6.4 5.7 7.8 5.5 7.6 9.3 8.0 5.6 6.1 4.8 4.4 3.9 8.4 5.7 4.3 3.3 5.6 4.5 4.4 13.2 6.7 4.1 6.8 11.0 7.6 7.2 8.1 4.7 4.7 3.4 7.5 6.6 5.9 9.2 10.4 11.6 3.2 8.1 10.8 7.3 9.7 5.1 8.2 9.5 9.8 7.0 6.6 9.0 12.2 11.9 10.8 16.0 8.5 11.6 6.8 7.9 17.3 12.3 5.5 8.0 15.4 6.0 19.5 10.8 16.3 12.3 17.3 5.4 10.6 5.9 13.2 18.2 5.6 17.8 6.2 9.2 1.8 14.9 14.5 8.9 4.3 7.5 7.0 13.2 6.3 6.0 13.6 22.8 5.1 5.6 9.4 11.1 5.7 9.7 5.5 10.4 8.2 12.7 14.0 6.1 10.6 11.1 7.5 51.1 34.4 30.2 37.4 42.8 31.0 18.4 31.6 28.3 21.4 24.8 25.5 25.5 35.2 24.2 39.9 18.5 29.8 17.8 7.8 7.8 7.0 8.2 7.5 6.4 9.3 8.0 8.4 6.8 8.1 9.2 3.4 0.0 1.7 1.0 5.4 12.7 2.6 1.7 2.2 5.7 4.2 3.2 2.3 1.5 1.5 3.7 0.0 3.7 5.9 4.6 1.9 4.4 17.7 1.9 3.2 5.2 7.2 1.7 2.7 3.7 4.0 3.2 2.0 2.7 8.2 3.0 6.1 6.3 6.1 5.0 2.8 5.0 0.0 8.8 8.9 39.3 6.2 4.7 3.6 1.0 6.8 3.4 11.3 3.5 2.9 5.1 3.2 7.9 4.0 4.9 4.6 4.2 1.7 2.0 0.0 1.9 3.1 1.5 5.1 2.7 13.9 4.5 6.7 3.0 4.1 1.9 BMP8A OP-2 ENSG00000183682 "Bone morphogenetic protein 8a" Q7Z5Y6 1 39491636-39529869 "Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 10 "thyroid gland: 91.6" "Group enriched" "Detected in some" 7 "Early spermatids: 42.2;Late spermatids: 164.4" "Cancer enhanced" "Detected in many" "thyroid cancer: 4.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HHSteC: 7.0;HL-60: 5.8;U-2197: 22.2;U-266/70: 8.6;U-266/84: 7.9" HPA047254 Approved Vesicles "Secreted to blood" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "HPA047254: " "unprognostic (9.62e-3)" "unprognostic (2.11e-2)" "unprognostic (7.79e-2)" "unprognostic (1.22e-1)" "unprognostic (1.37e-1)" "unprognostic (2.00e-1)" "unprognostic (2.91e-3)" "unprognostic (1.74e-1)" "unprognostic (1.21e-1)" "unprognostic (1.03e-1)" "unprognostic (1.54e-1)" "unprognostic (5.33e-3)" "unprognostic (2.95e-9)" "unprognostic (2.62e-2)" "unprognostic (1.49e-1)" "unprognostic (2.28e-3)" "unprognostic (2.55e-2)" 0.5 0.8 2.1 1.4 3.7 1.3 0.2 2.7 3.7 2.3 0.0 1.0 1.4 3.3 3.8 0.5 3.4 1.2 1.1 2.7 1.6 0.9 0.3 0.4 1.8 7.0 3.5 2.9 2.6 0.8 0.5 0.4 4.7 1.2 0.6 1.8 1.2 3.5 2.6 1.7 2.1 5.1 4.1 1.6 0.9 3.3 3.2 5.8 91.6 0.1 0.5 0.9 0.5 9.4 0.4 1.1 0.8 0.5 0.1 0.1 0.6 0.2 0.0 0.0 0.0 1.2 0.2 0.3 0.1 0.1 0.1 1.0 0.0 0.0 0.0 0.8 1.0 0.1 2.0 0.1 7.0 5.8 0.2 0.2 0.0 0.0 0.0 0.1 0.0 2.2 0.3 3.7 0.0 1.6 0.2 1.2 2.0 0.2 0.1 0.8 0.1 3.2 0.0 0.3 1.2 0.2 0.3 0.3 0.5 1.0 1.0 1.1 0.2 0.1 0.8 22.2 0.1 8.6 7.9 0.5 0.2 0.7 0.1 0.8 0.1 0.0 0.1 0.1 0.0 0.3 0.1 0.0 0.0 0.3 0.1 0.1 0.4 0.2 0.1 0.1 0.0 0.0 2.1 3.7 2.7 3.7 2.7 1.6 7.0 3.5 4.7 4.1 3.2 9.4 0.0 0.0 0.0 0.7 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 42.2 0.0 0.2 0.1 0.0 0.0 5.7 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 164.4 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 14.1 0.0 0.0 0.7 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.6 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 BMPR1B "ALK6, CDw293" ENSG00000138696 "Bone morphogenetic protein receptor type 1B" O00238 4 94757955-95158448 "CD markers, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Chondrogenesis "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 20.1;cervix: 24.7;prostate: 22.4" "Cell type enriched" "Detected in many" 7 "Astrocytes: 480.6" "Cancer enhanced" "Detected in many" "breast cancer: 32.4;prostate cancer: 24.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 22.0;MCF7: 11.1;SH-SY5Y: 18.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "unprognostic (2.25e-1)" "unprognostic (1.80e-2)" "unprognostic (1.40e-3)" "prognostic favorable (2.84e-4)" "unprognostic (1.57e-1)" "unprognostic (4.22e-2)" "unprognostic (1.92e-1)" "unprognostic (2.86e-2)" "unprognostic (2.95e-2)" "unprognostic (1.01e-1)" "unprognostic (3.97e-2)" "unprognostic (3.93e-1)" "unprognostic (1.62e-3)" "unprognostic (7.89e-4)" "unprognostic (6.22e-2)" "unprognostic (3.81e-3)" "unprognostic (2.63e-2)" 0.7 4.6 13.4 0.3 15.4 0.1 1.0 13.5 15.0 24.7 2.1 0.9 0.1 4.4 2.4 0.2 12.5 2.6 0.8 12.5 16.0 7.8 0.8 1.7 0.0 19.3 20.1 6.2 1.1 0.1 1.9 0.7 17.5 22.4 0.2 8.1 1.0 14.2 3.0 0.8 0.1 0.6 15.3 0.9 2.4 3.7 15.6 6.4 0.5 1.1 0.0 0.2 0.5 12.1 0.0 22.0 5.6 0.0 2.3 4.8 0.2 0.1 0.0 0.1 0.5 0.0 0.1 0.0 0.2 1.0 0.0 1.3 3.6 8.4 0.1 0.0 4.9 0.0 1.4 0.0 0.6 0.5 0.1 2.7 9.0 2.8 6.2 0.4 0.1 0.0 0.0 0.0 7.1 11.1 0.6 0.1 2.1 0.1 3.2 0.2 3.4 0.1 4.3 0.1 0.2 18.8 0.3 3.2 3.2 0.8 1.7 0.0 0.0 4.0 3.8 0.2 4.3 0.0 0.0 0.0 1.5 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.2 0.0 13.4 15.4 13.5 15.0 12.5 16.0 19.3 20.1 17.5 15.3 15.6 12.1 0.0 6.4 0.0 480.6 0.0 2.7 1.3 13.1 1.2 0.4 3.8 1.0 3.4 2.8 33.4 60.7 0.0 0.0 0.0 0.0 1.9 3.0 1.4 28.5 1.4 1.1 18.4 0.0 51.0 0.4 0.3 1.5 0.0 20.8 0.0 38.6 2.9 0.0 0.1 0.0 2.5 0.0 8.2 0.0 1.2 1.4 3.1 0.4 28.4 22.5 0.0 38.5 0.0 10.1 2.8 0.7 0.0 3.8 0.0 28.5 0.0 0.2 15.7 1.6 0.0 1.7 2.9 1.2 10.6 0.4 2.3 0.0 0.5 4.4 0.0 1.6 BOK "BCL2L9, BOKL, MGC4631" ENSG00000176720 "BCL2 family apoptosis regulator BOK" Q9UMX3 2 241551424-241574131 "Plasma proteins, Predicted membrane proteins, Transporters" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 218.8" "Cell type enhanced" "Detected in many" "Hepatocytes: 100.8;Oligodendrocytes: 47.0;Proximal tubular cells: 41.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 2.3" "Lineage enhanced" "Detected in single" "T-cells: 2.3" "Cell line enhanced" "Detected in many" "TIME: 65.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 15: Liver - Metabolism" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (6.16e-2)" "unprognostic (3.01e-2)" "unprognostic (1.24e-3)" "unprognostic (6.30e-2)" "unprognostic (8.63e-2)" "unprognostic (1.33e-1)" "unprognostic (2.24e-3)" "unprognostic (1.16e-2)" "unprognostic (8.45e-2)" "unprognostic (2.33e-1)" "unprognostic (2.47e-2)" "unprognostic (2.27e-1)" "prognostic favorable (1.09e-9)" "unprognostic (9.48e-3)" "unprognostic (6.81e-2)" "unprognostic (2.46e-1)" "unprognostic (1.09e-1)" 90.6 7.1 88.4 6.2 138.6 0.4 37.7 110.4 110.3 15.6 51.0 38.0 8.1 34.2 16.3 29.5 18.1 22.7 6.3 77.0 87.8 20.5 97.0 20.1 3.7 146.6 120.6 9.9 16.3 3.8 4.7 5.7 127.1 28.5 5.0 1.2 11.8 25.5 2.6 20.0 9.4 20.4 98.5 6.5 21.5 7.7 115.4 1.1 11.0 3.2 3.4 34.9 18.6 218.8 36.0 8.8 15.7 36.2 26.3 15.6 4.4 28.6 11.3 36.9 37.9 16.2 14.6 0.1 9.7 51.0 9.0 32.9 1.7 28.9 13.8 0.1 0.3 0.1 9.3 42.2 21.8 0.2 1.3 15.9 29.2 15.5 4.4 27.8 44.6 2.4 6.4 0.1 36.7 46.0 0.2 0.2 9.9 40.0 26.8 0.4 25.9 0.2 24.2 0.9 14.0 5.4 13.2 8.5 23.3 18.3 24.4 1.3 65.0 0.1 52.8 0.7 3.2 0.1 0.1 0.1 0.1 0.0 2.1 0.0 0.0 0.0 2.3 0.0 0.2 0.0 0.7 1.0 0.0 0.0 0.0 1.1 0.0 0.7 0.0 0.0 0.0 0.6 88.4 138.6 110.4 110.3 77.0 87.8 146.6 120.6 127.1 98.5 115.4 218.8 22.5 6.4 32.1 0.3 0.5 7.1 11.5 8.6 5.2 0.2 19.4 10.5 10.2 32.9 6.3 11.0 0.0 2.0 2.5 5.8 15.6 23.2 0.2 6.6 17.6 15.6 11.4 5.3 0.8 11.1 10.5 10.9 5.6 14.4 0.0 2.6 12.5 100.8 0.7 0.0 1.5 3.7 2.0 4.7 1.2 1.5 6.2 0.7 1.8 4.7 0.0 3.9 6.2 7.5 47.0 27.7 2.8 10.5 0.9 26.3 7.1 41.9 1.5 1.3 0.0 11.7 11.2 0.3 8.2 19.8 12.8 6.2 1.6 3.4 6.1 15.1 BPIFA3 "bA49G10.4, C20orf71, SPLUNC3" ENSG00000131059 "BPI fold containing family A member 3" Q9BQP9 20 33217310-33227806 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 537 "testis: 53.7" "Cell type enriched" "Detected in some" 4 "Late spermatids: 3057.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA062708 Enhanced "Secreted in male reproductive system" NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 25: Spermatids - Spermatogenesis" "HPA062708: AB_2684843" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 53.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 736.6 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3057.9 14.6 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.3 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 18.2 8.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 BRCA2 "BRCC2, FACD, FAD, FAD1, FANCD, FANCD1, XRCC11" ENSG00000139618 "BRCA2 DNA repair associated" P51587 13 32315086-32400268 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA recombination, DNA repair" DNA-binding "Cancer-related genes, Disease variant, Fanconi anemia, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.8;lymphoid tissue: 3.1;testis: 2.7" "Cell type enhanced" "Detected in many" "Spermatocytes: 115.4;Spermatogonia: 85.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" HPA026815 Uncertain Supported Nucleoplasm,Cytosol Yes No "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "HPA026815: AB_10602692" "unprognostic (9.36e-2)" "unprognostic (2.50e-1)" "unprognostic (4.50e-3)" "unprognostic (1.06e-2)" "unprognostic (5.40e-2)" "unprognostic (2.26e-2)" "unprognostic (1.37e-2)" "unprognostic (1.15e-1)" "unprognostic (1.60e-2)" "unprognostic (2.01e-1)" "unprognostic (6.97e-3)" "unprognostic (4.06e-2)" "unprognostic (3.07e-9)" "unprognostic (2.36e-2)" "unprognostic (1.18e-1)" "unprognostic (1.88e-1)" "unprognostic (1.32e-1)" 0.2 0.1 0.0 1.3 0.0 5.8 0.5 0.0 0.0 0.2 0.2 0.7 0.5 0.3 0.0 0.5 0.1 0.3 0.0 0.0 0.0 0.1 0.3 0.3 2.1 0.1 0.1 0.1 0.1 0.0 0.0 1.0 0.1 0.1 0.8 0.0 0.2 0.0 0.0 0.7 0.5 0.3 0.1 0.9 0.6 2.7 0.2 3.1 0.2 0.0 2.0 0.5 0.2 0.1 4.7 4.0 6.0 5.0 0.6 1.4 7.0 4.8 3.1 5.5 5.0 10.6 6.0 15.9 3.2 2.1 7.6 6.1 5.5 2.9 10.5 10.5 3.1 10.3 2.5 3.5 0.1 15.4 4.9 0.2 0.0 10.3 6.9 0.4 4.5 8.1 7.0 5.5 6.4 5.1 11.8 8.3 8.3 4.9 2.3 11.4 17.3 3.0 1.4 5.4 2.4 4.6 5.9 2.4 2.2 2.2 2.9 7.3 1.3 6.3 6.8 7.0 6.7 2.0 3.3 8.0 2.7 5.7 5.8 0.0 0.3 1.5 0.5 0.7 0.1 1.7 0.4 0.4 0.3 2.2 0.5 0.4 0.8 0.5 0.8 3.0 1.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.2 0.1 4.4 9.6 2.6 0.0 12.4 2.5 3.3 2.5 2.2 0.0 4.3 3.3 1.9 0.0 1.8 0.0 0.0 14.1 10.5 4.8 0.0 2.5 5.2 4.4 6.3 5.5 1.2 29.5 0.7 1.6 12.7 5.8 10.7 4.6 3.8 26.9 1.4 0.8 9.5 0.0 0.5 4.4 0.0 7.5 11.0 4.4 2.1 14.4 3.6 4.7 20.1 0.3 0.0 0.0 0.6 1.2 1.8 1.2 27.8 1.2 1.0 0.6 2.9 0.0 13.1 8.3 5.3 115.4 85.6 8.0 1.3 5.5 7.9 4.2 7.8 2.3 BRDT "BRD6, CT9" ENSG00000137948 "Bromodomain testis associated" Q58F21 1 91949343-92014426 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Meiosis, mRNA processing, mRNA splicing, Spermatogenesis, Transcription, Transcription regulation" "Activator, Chromatin regulator" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 48 "testis: 131.4" "Group enriched" "Detected in some" 4 "Early spermatids: 1313.5;Spermatocytes: 561.9" "Cancer enriched" "Detected in some" 5 "testis cancer: 6.4" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "basophil: 1.5" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in single" 30 "BEWO: 21.3" "Low region specificity" "Detected in all" "Not detected" "Not detected" CAB012237 Approved NA NA "Cluster 11: Basophils - Unknown function" "Cluster 74: Testis - Spermatogenesis" "Cluster 28: BEWO - Transcription regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "CAB012237: AB_304756" "unprognostic (5.00e-2)" "unprognostic (2.86e-1)" "unprognostic (2.22e-3)" "unprognostic (2.24e-1)" "unprognostic (1.49e-1)" "unprognostic (5.25e-2)" "unprognostic (2.53e-3)" "unprognostic (6.26e-2)" "unprognostic (1.97e-1)" "unprognostic (4.22e-13)" "unprognostic (2.70e-1)" "unprognostic (1.77e-1)" "unprognostic (1.75e-1)" "unprognostic (2.00e-3)" 0.0 0.0 0.3 0.5 0.5 2.7 0.3 0.8 0.7 0.1 0.5 0.1 0.4 0.1 0.2 0.0 0.0 0.4 0.0 0.5 0.3 0.0 0.1 0.2 0.4 0.5 0.1 0.1 0.0 0.0 0.0 0.9 0.4 0.1 0.0 0.3 0.2 0.1 0.0 0.6 0.0 0.1 0.1 0.2 0.1 131.4 0.6 0.2 0.2 0.0 0.0 0.2 0.0 0.9 0.2 0.0 0.0 0.1 0.0 0.0 21.3 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.1 0.4 0.0 0.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.3 0.4 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.7 0.2 0.1 0.1 0.0 0.0 0.1 0.2 0.3 0.0 0.1 0.1 0.2 0.0 0.1 0.1 0.0 0.1 0.0 0.0 1.5 0.3 0.2 0.3 0.1 0.3 0.1 0.1 0.1 0.0 0.2 0.2 0.2 0.8 0.3 0.1 0.2 0.1 0.2 0.3 0.5 0.8 0.7 0.5 0.3 0.5 0.1 0.4 0.1 0.6 0.9 0.0 0.0 0.0 1.6 0.0 0.0 0.2 0.0 0.0 0.0 1.2 1.1 0.6 0.0 0.0 0.0 0.0 38.0 1.7 0.0 0.0 0.0 1313.5 0.0 0.0 1.8 0.0 0.0 1.2 0.0 22.2 3.2 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.9 0.0 0.0 0.0 0.0 228.7 7.8 0.8 0.0 0.0 0.0 0.0 1.0 1.0 0.3 0.0 0.0 6.8 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.2 2.3 561.9 19.9 0.0 0.0 19.4 1.1 0.1 0.0 0.1 BSPRY FLJ20150 ENSG00000119411 "B-box and SPRY domain containing" Q5W0U4 9 113349541-113371233 "Predicted intracellular proteins" "Calcium transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "parathyroid gland: 447.2" "Cell type enhanced" "Detected in many" "Breast glandular cells: 61.9;Ductal cells: 66.8;Exocrine glandular cells: 65.8;Pancreatic endocrine cells: 48.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 21 "plasmacytoid DC: 4.4" "Lineage enriched" "Detected in single" 21 "dendritic cells: 4.4" "Cell line enhanced" "Detected in many" "A-431: 41.8;CAPAN-2: 25.9;MCF7: 62.0;OE19: 70.9;RPMI-8226: 32.3;SK-BR-3: 29.9;T-47d: 30.3" "Not detected" "Not detected" "Region enriched" "Detected in single" 6 "cerebellum: 3.8" "HPA042889, HPA077485" Approved Uncertain Nucleoplasm,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 21: OE19 - Mitochondria" "Cluster 1: Pancreatic cells - Digestion" Nucleoplasm Cytosol "HPA042889: AB_10795515, HPA077485: " "unprognostic (1.32e-1)" "unprognostic (3.09e-2)" "unprognostic (1.18e-1)" "unprognostic (2.20e-3)" "unprognostic (1.68e-1)" "unprognostic (2.10e-3)" "unprognostic (4.29e-1)" "unprognostic (1.67e-1)" "unprognostic (1.17e-1)" "unprognostic (2.71e-1)" "unprognostic (2.28e-1)" "unprognostic (1.95e-2)" "prognostic favorable (4.56e-14)" "unprognostic (1.15e-3)" "unprognostic (2.36e-1)" "unprognostic (1.38e-1)" "unprognostic (1.70e-1)" 0.3 3.1 3.7 2.6 11.3 5.9 14.6 5.9 4.2 6.5 1.2 12.0 8.8 1.1 10.9 30.1 4.4 4.4 1.5 2.5 3.0 14.4 0.8 5.6 0.8 2.1 4.8 0.0 41.7 447.2 8.3 1.7 1.7 5.0 11.0 6.9 81.6 4.5 0.0 26.3 7.0 0.7 1.7 0.5 24.7 2.8 5.9 1.8 30.3 0.1 3.1 3.0 7.6 2.5 41.8 0.0 0.0 0.0 0.0 0.0 15.8 0.0 0.0 0.0 0.0 8.6 25.9 0.0 0.4 0.0 0.0 3.6 0.4 0.0 0.0 4.6 3.1 0.2 0.0 0.2 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 20.8 0.3 0.0 0.0 62.0 0.7 0.0 1.0 70.9 0.0 0.9 0.0 32.3 4.0 8.8 13.7 0.0 0.0 29.9 0.0 1.7 30.3 4.3 0.0 0.0 0.0 0.1 0.0 9.7 13.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.4 0.0 0.0 3.7 11.3 5.9 4.2 2.5 3.0 2.1 4.8 1.7 1.7 5.9 2.5 0.3 6.4 6.9 0.0 2.5 1.0 2.0 4.4 0.0 1.8 61.9 31.2 2.8 17.2 9.5 27.6 6.2 9.2 9.9 20.8 39.2 66.8 0.5 11.3 1.6 0.9 20.4 15.6 1.0 65.8 1.1 0.7 21.4 17.3 3.8 1.5 0.0 0.8 1.4 0.0 3.2 19.1 12.2 0.3 0.3 0.6 0.0 0.5 10.6 0.0 1.0 0.8 3.1 0.5 0.2 48.6 14.5 0.0 2.5 13.8 13.5 21.2 9.7 12.1 0.0 0.0 1.7 0.6 4.3 26.4 14.2 6.7 1.3 0.1 24.9 17.7 BTBD11 "ABTB2B, FLJ33957" ENSG00000151136 "BTB domain containing 11" A6QL63 12 107318421-107659642 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 100.3" "Cell type enriched" "Detected in many" 9 "Inhibitory neurons: 266.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 3.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A549: 25.0;Hep G2: 13.6;MOLT-4: 17.9;PC-3: 12.3;RT4: 11.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055898, HPA061334" Supported Nucleoplasm,Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm Cytosol "HPA055898: AB_2682964, HPA061334: " "unprognostic (3.40e-2)" "unprognostic (4.06e-1)" "unprognostic (2.37e-1)" "unprognostic (7.85e-2)" "unprognostic (8.78e-3)" "unprognostic (4.82e-2)" "unprognostic (3.52e-1)" "unprognostic (2.12e-1)" "unprognostic (1.52e-1)" "unprognostic (5.92e-2)" "unprognostic (5.33e-2)" "unprognostic (1.78e-1)" "unprognostic (4.92e-8)" "unprognostic (2.66e-1)" "unprognostic (1.55e-1)" "unprognostic (3.33e-2)" "unprognostic (9.07e-3)" 0.4 0.7 7.2 2.7 4.3 4.4 2.9 5.5 10.9 8.1 5.9 0.6 0.7 0.9 1.2 29.4 0.3 0.9 0.6 2.9 13.2 4.2 1.1 0.6 2.9 24.3 16.0 0.1 0.8 100.3 3.5 2.0 24.4 3.4 0.6 1.9 5.6 1.3 0.5 11.1 1.4 0.5 11.4 1.4 0.6 0.7 21.7 17.2 18.9 0.2 3.3 1.7 11.1 5.3 0.1 25.0 5.0 0.0 1.8 0.5 0.0 0.6 0.0 0.2 0.0 0.3 4.0 0.0 6.1 0.1 2.4 9.2 5.1 9.5 0.3 0.0 1.6 0.0 0.1 13.6 0.0 0.2 0.1 2.0 4.0 0.0 2.9 3.8 0.7 10.5 0.0 0.0 0.2 0.9 17.9 2.0 5.3 0.5 12.3 0.0 8.1 0.0 0.0 11.4 6.8 2.5 0.0 0.2 0.0 0.4 0.5 0.7 1.0 0.1 0.2 0.0 2.0 0.1 0.0 0.1 6.4 2.6 0.0 0.9 0.4 0.5 1.0 0.1 3.5 0.0 1.1 0.6 0.7 0.1 1.4 1.3 1.3 0.1 0.3 0.1 0.6 0.6 7.2 4.3 5.5 10.9 2.9 13.2 24.3 16.0 24.4 11.4 21.7 5.3 0.3 0.0 0.0 17.3 0.3 5.2 3.7 2.5 6.8 3.5 0.7 3.2 2.9 0.0 3.0 0.0 0.0 0.2 1.2 0.0 0.0 0.8 0.0 1.2 1.9 0.3 3.5 1.3 8.7 0.0 0.0 1.5 0.0 2.3 0.0 0.0 0.0 0.9 0.3 1.7 266.4 0.4 0.0 0.6 4.3 0.0 0.6 1.7 0.0 1.0 1.8 0.2 3.1 12.5 1.9 0.3 0.0 4.1 0.7 2.8 0.2 0.9 0.3 0.4 0.0 0.0 1.1 0.1 0.2 27.5 7.7 0.4 4.5 3.4 0.4 3.4 BTD ENSG00000169814 Biotinidase P43251 3 15601341-15722311 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 95.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052275 Uncertain "Secreted to blood" NA NA 2800000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA052275: AB_2681782" "unprognostic (6.04e-2)" "unprognostic (2.42e-1)" "unprognostic (9.37e-3)" "unprognostic (5.84e-2)" "unprognostic (2.13e-1)" "unprognostic (1.95e-2)" "unprognostic (6.37e-3)" "unprognostic (4.26e-2)" "unprognostic (3.29e-2)" "unprognostic (1.23e-2)" "unprognostic (1.05e-2)" "unprognostic (1.29e-1)" "prognostic favorable (2.60e-9)" "unprognostic (2.44e-2)" "unprognostic (4.90e-2)" "unprognostic (1.67e-3)" "unprognostic (3.73e-2)" 25.3 16.7 10.7 8.0 12.7 13.1 16.4 20.2 12.6 13.7 11.0 15.9 46.1 13.2 62.4 9.9 18.3 19.9 10.2 11.5 10.3 37.6 95.9 15.9 9.6 12.0 10.0 25.3 44.1 27.7 5.9 17.0 12.6 19.5 17.0 35.2 16.0 21.1 7.8 9.5 30.7 14.1 10.3 11.3 24.4 18.2 9.9 10.6 26.8 11.4 10.4 14.3 7.5 19.1 9.2 22.0 7.8 7.3 51.7 15.3 39.6 15.4 18.4 16.2 28.3 10.1 21.5 4.1 16.3 31.6 7.1 9.7 5.3 16.7 18.7 7.6 11.7 12.9 28.8 24.8 12.7 8.8 14.7 18.3 16.9 42.9 5.1 39.7 30.5 5.9 8.7 32.3 44.7 11.1 4.5 8.2 8.5 16.9 13.0 5.9 18.4 27.9 16.5 17.7 5.3 11.8 17.9 5.2 24.4 15.1 19.9 11.3 24.3 20.5 13.6 19.1 10.1 8.9 11.4 4.1 21.4 7.7 14.4 74.1 20.7 44.9 22.9 19.6 21.0 14.7 23.3 19.2 21.4 13.1 19.7 15.4 19.8 15.0 15.8 24.9 28.8 16.5 10.7 12.7 20.2 12.6 11.5 10.3 12.0 10.0 12.6 10.3 9.9 19.1 14.9 6.4 11.0 11.8 11.7 5.9 12.4 25.0 6.2 13.5 9.1 7.9 6.0 45.8 16.7 18.4 18.8 25.3 19.7 9.9 5.9 21.1 31.0 9.5 6.0 9.1 7.2 4.0 6.6 28.5 22.4 14.5 9.7 5.7 5.1 8.9 20.3 63.3 14.9 5.0 12.2 8.5 16.2 8.2 5.9 17.9 32.3 9.2 10.6 5.6 8.7 19.2 6.2 27.2 23.9 12.0 17.9 18.0 16.6 6.3 52.1 32.0 19.8 54.1 13.1 8.5 8.6 45.3 7.5 7.7 5.5 23.1 13.6 17.4 8.9 9.5 C10orf105 FLJ00245 ENSG00000214688 "Chromosome 10 open reading frame 105" Q8TEF2 10 71711701-71737824 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "brain: 34.6" "Group enriched" "Detected in some" 4 "Early spermatids: 8.7;Langerhans cells: 2.4;Late spermatids: 5.1;Melanocytes: 3.6" "Cancer enriched" "Detected in single" 9 "glioma: 0.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.8;non-classical monocyte: 2.1" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in single" 5 "BJ hTERT+: 3.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 29: Early spermatids - Spermatogenesis" "unprognostic (2.60e-3)" "unprognostic (6.76e-3)" "unprognostic (5.45e-1)" "unprognostic (4.14e-1)" "unprognostic (1.17e-1)" "unprognostic (1.37e-6)" "unprognostic (5.25e-2)" "unprognostic (2.10e-3)" "unprognostic (1.47e-1)" "unprognostic (8.08e-2)" "unprognostic (3.87e-2)" "unprognostic (1.35e-1)" "unprognostic (7.37e-2)" "unprognostic (4.64e-1)" "unprognostic (1.53e-1)" "unprognostic (1.04e-1)" "unprognostic (1.52e-1)" 0.6 0.0 14.4 0.7 15.0 0.5 0.1 13.8 7.7 0.2 4.2 0.1 0.2 0.1 0.0 0.1 0.4 0.2 0.2 9.2 19.4 0.0 0.1 0.5 1.1 27.3 34.6 0.5 0.0 0.0 0.1 0.1 19.2 0.1 0.1 0.1 0.1 0.0 0.1 0.4 0.2 0.0 17.3 2.8 0.1 1.4 22.5 0.5 0.0 0.1 0.4 0.1 0.2 13.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.3 0.0 2.1 0.0 0.0 0.1 14.4 15.0 13.8 7.7 9.2 19.4 27.3 34.6 19.2 17.3 22.5 13.6 0.4 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 2.4 5.1 0.0 0.7 3.6 0.0 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.1 C10orf67 "bA215C7.4, C10orf115, LINC01552, MGC46732" ENSG00000179133 "Chromosome 10 open reading frame 67" Q8IYJ2 10 23202696-23344845 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 5.1;fallopian tube: 4.8;testis: 12.4" "Group enriched" "Detected in some" 5 "Alveolar cells type 1: 38.5;Early spermatids: 40.2;Endometrial ciliated cells: 18.2;Late spermatids: 32.8;Proximal tubular cells: 17.9;Respiratory ciliated cells: 35.7;Spermatocytes: 70.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "T-reg: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "HaCaT: 3.0;SiHa: 3.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA038131 Approved Approved Vesicles,Microtubules,Mitochondria NA No "Cluster 35: T-regs - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 49: Ciliated cells - Cilium organization" "Vesicles, Microtubules, Mitochondria" "HPA038131: AB_10670658" "unprognostic (4.76e-4)" "unprognostic (2.38e-1)" "unprognostic (3.75e-2)" "unprognostic (2.92e-2)" "unprognostic (9.67e-3)" "unprognostic (1.91e-1)" "unprognostic (1.54e-1)" "unprognostic (1.78e-2)" "unprognostic (8.56e-2)" "unprognostic (1.78e-1)" "unprognostic (1.24e-2)" "unprognostic (2.46e-3)" "unprognostic (3.98e-1)" "unprognostic (3.59e-2)" "unprognostic (3.84e-3)" "unprognostic (9.58e-2)" 0.0 0.2 1.5 0.2 1.4 0.3 0.1 0.9 1.6 0.1 5.1 0.1 0.5 0.2 1.4 0.1 4.8 0.2 0.7 1.7 1.3 3.5 0.4 2.9 0.3 2.0 2.2 0.5 0.2 0.4 1.2 0.1 1.5 0.0 0.0 0.9 0.1 0.1 0.5 1.3 0.3 0.0 1.3 0.2 0.1 12.4 1.9 0.0 0.6 0.1 0.1 0.0 0.0 2.0 0.7 0.1 0.9 0.1 0.0 0.2 0.3 0.1 0.0 0.9 0.8 0.2 1.3 0.1 0.1 0.8 0.1 3.0 0.1 0.3 0.8 0.3 0.2 0.3 0.7 0.2 0.5 0.1 0.2 0.2 1.0 0.3 0.4 0.1 0.0 0.1 0.3 0.5 0.0 0.3 0.1 0.2 0.5 0.0 0.1 0.1 0.1 0.1 0.7 0.2 0.5 0.2 3.9 0.1 0.0 0.1 0.2 0.2 0.2 0.2 0.8 0.2 0.1 0.5 0.1 0.0 1.1 0.1 0.2 0.1 0.0 0.1 0.1 0.0 0.1 0.2 0.3 0.2 0.0 0.3 0.2 0.2 0.0 0.2 0.1 0.2 1.2 0.0 1.5 1.4 0.9 1.6 1.7 1.3 2.0 2.2 1.5 1.3 1.9 2.0 0.0 38.5 2.4 0.3 0.0 2.8 0.1 1.9 0.0 0.4 0.0 0.0 1.8 0.0 2.5 0.0 0.0 0.0 0.0 0.0 1.9 0.2 40.2 18.2 0.2 0.1 0.0 0.0 4.7 0.2 0.0 0.2 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 32.8 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.5 2.2 0.2 0.0 0.7 0.0 0.0 0.0 17.9 35.7 1.6 6.6 0.0 0.1 70.1 5.2 0.0 1.3 0.0 0.3 0.5 0.1 0.0 C10orf82 "Em:AC016825.4, MGC33547" ENSG00000165863 "Chromosome 10 open reading frame 82" Q8WW14 10 116663696-116670264 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "testis: 84.5" "Group enriched" "Detected in some" 113 "Early spermatids: 1053.9;Late spermatids: 1926.7" "Cancer enhanced" "Detected in many" "breast cancer: 2.4" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 103 "basophil: 10.2" "Lineage enriched" "Detected in single" 103 "granulocytes: 10.2" "Cell line enhanced" "Detected in some" "BEWO: 1.2;Hep G2: 2.8;NTERA-2: 1.4;SuSa: 2.5;T-47d: 3.5" "Not detected" "Not detected" HPA043022 Approved Mitochondria Yes NA "Cluster 46: Basophils - DNA binding" "Cluster 83: Testis - Spermatogenesis" "Cluster 6: T47d - Mammary gland" "Cluster 34: Spermatids - Unknown function" Mitochondria "HPA043022: " "unprognostic (9.98e-2)" "unprognostic (2.09e-2)" "unprognostic (8.41e-2)" "unprognostic (2.11e-1)" "unprognostic (1.63e-2)" "unprognostic (9.52e-2)" "unprognostic (3.46e-3)" "unprognostic (3.48e-1)" "unprognostic (6.15e-2)" "unprognostic (1.50e-2)" "unprognostic (8.00e-2)" "unprognostic (1.47e-3)" "unprognostic (2.61e-2)" "unprognostic (1.94e-2)" "unprognostic (1.73e-1)" "unprognostic (1.07e-1)" 0.3 1.7 0.3 0.2 0.2 0.0 0.9 0.1 0.4 0.4 0.0 0.9 0.1 0.0 0.2 0.3 0.2 0.1 0.4 0.2 0.8 1.2 0.0 0.0 0.0 0.3 0.5 3.6 1.1 0.0 1.0 0.0 0.4 0.9 0.2 0.1 0.2 0.7 0.0 0.2 0.4 0.0 0.2 0.1 0.4 84.5 0.9 0.0 1.6 0.1 0.0 0.3 0.6 0.2 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.5 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.1 0.4 0.2 0.8 0.3 0.5 0.4 0.2 0.9 0.2 0.0 0.0 0.0 0.3 0.0 0.1 0.4 0.0 0.0 0.0 1.1 1.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 1053.9 0.3 0.2 0.5 1.2 0.0 0.5 0.2 0.1 0.1 0.0 0.7 0.0 5.6 0.0 0.0 0.1 0.0 1.8 1.1 0.0 0.0 0.0 1926.7 9.0 0.6 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 5.3 0.0 0.7 0.1 0.1 0.0 0.0 13.1 0.4 0.2 10.5 8.0 0.0 0.0 0.0 0.1 8.0 1.2 0.3 C11orf94 ENSG00000234776 "Chromosome 11 open reading frame 94" C9JXX5 11 45906513-45907272 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 148 "testis: 54.7" "Group enriched" "Detected in some" 82 "Early spermatids: 390.0;Late spermatids: 189.9" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" "unprognostic (1.55e-1)" "unprognostic (2.71e-1)" "unprognostic (2.28e-1)" "unprognostic (2.36e-1)" "unprognostic (7.28e-2)" "unprognostic (5.99e-2)" "unprognostic (6.21e-3)" "unprognostic (1.97e-1)" "unprognostic (1.43e-1)" "unprognostic (7.11e-2)" "unprognostic (3.33e-2)" "unprognostic (4.24e-2)" "unprognostic (9.05e-4)" "unprognostic (1.90e-1)" "unprognostic (1.10e-1)" "unprognostic (3.28e-1)" "unprognostic (1.47e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.1 390.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 189.9 1.8 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 3.5 1.6 0.0 0.0 0.0 0.0 0.1 0.2 0.1 C12orf54 MGC35033 ENSG00000177627 "Chromosome 12 open reading frame 54" Q6X4T0 12 48482498-48496524 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 39 "testis: 40.4" "Cell type enriched" "Detected in many" 4 "Late spermatids: 2541.6" "Cancer enhanced" "Detected in some" "cervical cancer: 2.9;head and neck cancer: 2.1" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HBEC3-KT: 2.7" "Not detected" "Not detected" HPA073090 Approved "Intermediate filaments" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 25: Spermatids - Spermatogenesis" "Intermediate filaments" "HPA073090: " "unprognostic (2.59e-3)" "unprognostic (5.49e-2)" "unprognostic (7.94e-3)" "unprognostic (2.60e-2)" "unprognostic (2.48e-2)" "unprognostic (8.99e-2)" "unprognostic (5.96e-2)" "unprognostic (1.62e-1)" "unprognostic (8.01e-2)" "unprognostic (1.36e-4)" "unprognostic (2.37e-1)" "unprognostic (5.06e-3)" "unprognostic (7.53e-2)" "unprognostic (1.34e-1)" "unprognostic (1.97e-1)" "unprognostic (1.92e-1)" 0.0 0.4 0.3 0.0 0.4 0.0 0.2 0.2 1.0 0.1 0.0 0.1 0.0 0.2 0.0 0.4 0.1 0.1 0.0 0.3 0.2 0.0 0.0 0.1 0.0 0.5 0.4 0.5 0.0 0.0 0.0 0.1 0.5 0.2 0.1 0.2 0.0 0.3 0.0 0.1 0.0 0.3 0.3 0.1 0.0 40.4 0.3 0.0 0.0 0.2 0.6 0.2 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.2 1.0 0.3 0.2 0.5 0.4 0.5 0.3 0.3 0.5 0.0 0.0 2.6 8.1 0.0 5.1 38.6 19.5 1.2 0.2 0.2 0.1 0.7 0.0 4.5 0.0 0.0 0.1 0.0 0.0 1.9 0.1 543.1 0.0 0.0 1.2 0.0 0.0 5.3 0.0 0.2 0.4 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 9.1 0.0 2.0 0.0 1.8 2541.6 10.8 1.4 0.0 2.8 0.0 0.3 0.0 4.5 2.5 0.0 0.0 13.2 0.0 6.4 0.0 1.9 1.9 0.2 6.6 4.3 1.0 11.5 6.5 5.9 2.3 0.0 0.5 0.4 0.0 10.8 C15orf48 "COXFA4L3, MIR147BHG, NMES1" ENSG00000166920 "Chromosome 15 open reading frame 48" Q9C002 15 45430579-45448761 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "intestine: 924.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 2962.4;Exocrine glandular cells: 2020.8;Langerhans cells: 2043.7;Pancreatic endocrine cells: 3493.6;Paneth cells: 2254.4;Proximal enterocytes: 2942.0;Undifferentiated cells: 1875.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.3;intermediate monocyte: 1.6;myeloid DC: 1.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 70.9;CAPAN-2: 128.8;GAMG: 126.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA012943 Enhanced NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA012943: AB_2668774" "unprognostic (5.29e-3)" "unprognostic (1.76e-1)" "unprognostic (2.08e-1)" "unprognostic (7.83e-2)" "unprognostic (1.17e-1)" "unprognostic (9.74e-3)" "unprognostic (1.48e-3)" "unprognostic (1.28e-3)" "unprognostic (1.59e-1)" "unprognostic (1.15e-1)" "unprognostic (4.93e-3)" "unprognostic (5.95e-2)" "unprognostic (8.86e-2)" "unprognostic (2.37e-1)" "unprognostic (6.51e-2)" "unprognostic (1.39e-1)" "unprognostic (3.66e-1)" 2.2 0.3 0.5 98.5 0.5 88.0 30.7 0.4 3.2 38.9 0.7 863.4 61.9 5.3 0.2 172.4 6.8 45.9 0.8 0.5 0.5 5.8 6.0 11.5 5.7 0.6 0.4 0.7 13.0 0.1 0.5 46.4 1.3 13.9 924.2 3.6 23.0 11.5 0.4 69.9 341.3 31.3 0.4 2.3 107.6 128.1 1.0 7.0 5.2 0.2 84.8 38.9 46.6 0.6 70.9 18.1 0.2 0.3 0.9 0.0 2.7 3.5 25.1 4.6 12.7 2.9 128.8 0.2 3.1 0.4 126.2 1.8 2.3 0.9 10.7 7.0 1.9 0.0 0.2 0.5 11.2 0.1 29.1 1.3 1.2 22.9 0.0 0.0 0.0 0.5 0.1 0.5 0.6 3.5 0.1 1.8 0.1 31.4 0.3 0.0 0.4 0.4 2.7 5.7 0.1 0.6 4.1 8.0 0.3 14.0 1.4 1.6 0.6 0.4 1.6 1.0 0.9 2.1 1.2 0.4 1.9 0.7 0.5 0.0 1.3 0.1 0.0 1.6 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.8 0.0 0.2 0.1 0.0 0.8 0.5 0.5 0.4 3.2 0.5 0.5 0.6 0.4 1.3 0.4 1.0 0.6 5.5 16.0 15.0 0.3 20.4 66.4 20.2 846.0 1.2 0.5 143.2 111.9 1.0 188.8 1117.6 5.5 0.0 286.2 7.4 2962.4 3.9 811.3 188.3 29.2 11.0 11.6 645.1 0.0 0.2 2020.8 450.3 16.4 250.2 67.7 33.0 0.2 1.4 3.7 398.4 114.4 0.1 1408.8 270.6 25.9 2043.7 235.4 7.2 388.4 58.7 0.0 489.4 0.7 1.0 0.5 0.4 3493.6 2254.4 7.5 4.1 200.5 2942.0 18.7 700.9 1.2 0.0 1.2 75.2 567.9 124.4 10.6 61.2 165.5 13.9 0.1 1875.4 633.4 C16orf71 "DKFZp686H2240, FLJ43261" ENSG00000166246 "Chromosome 16 open reading frame 71" Q8IYS4 16 4734344-4749396 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "fallopian tube: 22.5;testis: 74.0" "Cell type enhanced" "Detected in some" "Early spermatids: 37.1;Late spermatids: 62.0;Respiratory ciliated cells: 22.6;Spermatocytes: 122.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "MCF7: 4.6;U-2197: 5.0" "Low region specificity" "Detected in all" HPA049468 Enhanced Uncertain "Nuclear speckles" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 6: T47d - Mammary gland" "Cluster 66: Spermatocytes - Spermatogenesis" "Nuclear speckles" "HPA049468: AB_2680779" "unprognostic (1.24e-2)" "unprognostic (8.87e-2)" "unprognostic (2.39e-1)" "prognostic favorable (7.49e-4)" "unprognostic (7.06e-2)" "unprognostic (2.17e-2)" "unprognostic (5.36e-3)" "unprognostic (2.21e-2)" "unprognostic (1.69e-1)" "unprognostic (2.15e-2)" "unprognostic (6.79e-3)" "unprognostic (1.13e-1)" "unprognostic (8.56e-3)" "unprognostic (1.57e-1)" "unprognostic (1.61e-1)" "unprognostic (2.54e-5)" "unprognostic (1.65e-1)" 0.7 1.3 1.0 0.7 1.4 0.2 0.7 2.2 1.6 1.4 9.2 0.8 0.6 1.0 2.7 0.7 22.5 1.4 0.8 1.5 1.4 1.8 1.3 2.8 0.4 4.5 5.7 1.2 1.1 0.9 4.1 0.2 2.6 1.1 0.3 1.7 1.2 0.7 1.0 0.5 0.4 0.8 3.3 0.4 0.8 74.0 1.5 0.6 2.0 1.1 0.4 0.7 0.5 1.6 0.3 2.0 0.4 1.1 2.6 1.1 0.8 1.1 0.9 0.9 1.1 0.9 0.8 0.0 1.0 1.6 2.6 0.9 0.9 1.1 0.2 0.4 0.6 0.2 1.5 0.1 0.8 0.9 0.3 0.3 0.2 3.4 0.9 0.7 0.4 0.8 0.7 0.5 0.9 4.6 0.2 0.8 0.6 1.3 1.0 0.3 0.4 1.4 2.3 0.4 3.0 1.1 1.1 0.9 0.3 0.7 4.0 0.2 0.4 0.7 0.8 5.0 0.5 2.0 1.7 0.5 0.4 0.2 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.4 0.1 0.1 0.0 0.0 0.3 1.1 0.0 0.1 1.0 1.4 2.2 1.6 1.5 1.4 4.5 5.7 2.6 3.3 1.5 1.6 0.1 0.0 1.1 1.0 0.1 0.0 0.2 1.0 0.6 0.9 0.6 0.5 1.2 0.0 3.9 0.0 4.2 0.3 0.2 0.2 0.0 0.6 37.1 15.6 0.6 0.2 0.0 0.0 1.0 0.0 0.1 0.3 3.6 0.6 0.0 0.2 0.0 0.3 0.2 0.0 0.9 0.1 0.0 0.0 0.0 62.0 1.2 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.7 0.0 0.0 1.5 0.0 0.1 0.0 2.4 22.6 1.7 0.0 0.2 0.7 122.1 7.2 0.5 0.0 0.1 0.2 0.3 0.3 0.0 C16orf91 "CCSMST1, gs103, URLC5" ENSG00000174109 "Chromosome 16 open reading frame 91" Q4G0I0 16 1419752-1420756 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" "unprognostic (1.97e-2)" "unprognostic (4.62e-2)" "unprognostic (4.11e-3)" "unprognostic (6.35e-2)" "unprognostic (2.11e-1)" "unprognostic (2.10e-1)" "unprognostic (5.47e-3)" "unprognostic (5.21e-2)" "unprognostic (1.12e-2)" "unprognostic (1.26e-1)" "unprognostic (4.33e-1)" "unprognostic (7.12e-2)" "prognostic favorable (1.11e-4)" "unprognostic (9.81e-3)" "unprognostic (5.67e-2)" "unprognostic (4.19e-2)" "unprognostic (9.97e-2)" 7.2 14.4 13.3 4.4 13.7 8.0 7.6 13.5 14.5 6.2 14.2 8.7 7.7 7.1 5.8 9.9 7.9 4.6 12.5 13.9 13.6 10.2 12.4 5.2 8.0 13.5 13.2 6.4 8.4 7.7 5.2 7.0 13.8 6.5 6.2 5.8 6.2 7.6 14.0 10.6 7.6 6.3 13.1 8.0 8.2 7.9 13.6 10.1 5.6 16.0 7.7 7.9 6.6 13.6 16.6 31.4 11.3 11.9 18.1 13.6 13.4 12.9 13.8 23.3 19.4 30.3 26.2 15.7 18.8 15.1 17.4 16.6 20.6 21.5 12.9 15.7 29.6 8.9 31.3 24.3 24.7 24.3 12.0 14.9 35.1 22.2 23.5 11.1 19.4 27.1 27.4 25.2 13.8 42.3 20.7 21.3 19.4 26.4 23.0 32.6 11.1 39.1 19.5 8.8 13.9 19.4 16.6 26.1 17.4 7.5 23.8 46.6 12.2 12.1 9.3 9.5 14.6 17.5 20.8 31.2 10.3 15.8 14.6 27.1 23.5 12.5 31.7 23.2 34.0 42.9 28.8 24.5 26.9 32.9 33.6 26.6 12.8 40.2 15.8 37.6 25.2 18.1 13.3 13.7 13.5 14.5 13.9 13.6 13.5 13.2 13.8 13.1 13.6 13.6 20.5 6.4 6.7 3.3 21.8 44.4 26.8 36.7 25.0 13.8 30.8 34.7 13.8 21.5 21.1 7.3 12.5 33.8 27.0 22.3 45.0 23.4 3.9 21.4 20.5 21.0 15.6 21.2 5.8 20.7 26.9 16.6 13.7 19.6 15.2 23.2 13.9 21.6 21.6 13.5 5.4 23.5 26.4 10.9 15.7 2.0 13.1 11.2 16.0 1.0 23.7 26.3 25.7 4.0 5.0 22.6 16.6 11.3 21.3 39.8 21.0 25.0 29.6 25.2 13.1 21.9 18.5 20.7 22.5 35.8 61.1 36.9 22.3 30.8 29.1 30.1 C17orf107 ENSG00000205710 "Chromosome 17 open reading frame 107" Q6ZR85 17 4899418-4902934 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 16.6;pituitary gland: 27.0" "Cell type enriched" "Detected in many" 5 "Late spermatids: 288.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 9.0" "Immune cell enriched" "Detected in single" 7 "neutrophil: 2.9" "Lineage enriched" "Detected in single" 7 "granulocytes: 2.9" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 2.6;HMC-1: 3.2;hTCEpi: 3.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA069713 Uncertain Approved Nucleoplasm NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "HPA069713: AB_2686181" "prognostic favorable (5.06e-5)" "unprognostic (1.63e-1)" "unprognostic (2.43e-1)" "unprognostic (1.51e-2)" "unprognostic (5.83e-2)" "unprognostic (1.13e-3)" "unprognostic (9.61e-2)" "unprognostic (5.03e-2)" "unprognostic (4.15e-1)" "unprognostic (2.05e-1)" "prognostic favorable (8.61e-4)" "unprognostic (1.17e-1)" "prognostic favorable (2.68e-4)" "unprognostic (9.29e-2)" "unprognostic (2.65e-1)" "unprognostic (2.71e-1)" "unprognostic (3.12e-1)" 2.2 1.8 1.3 1.1 0.9 2.1 2.0 9.0 3.6 2.1 0.0 0.9 1.0 1.5 3.4 1.1 1.8 1.5 16.6 1.7 3.5 2.9 5.6 2.0 0.5 1.3 0.2 4.2 5.0 3.6 27.0 0.6 0.7 3.4 0.4 1.7 13.2 1.9 0.5 3.5 1.0 0.4 0.0 2.0 3.3 4.6 1.6 0.3 1.3 0.0 0.6 1.0 1.6 1.0 0.3 0.4 0.5 0.1 1.0 0.8 0.7 1.9 0.2 0.1 0.3 0.3 0.3 0.2 0.3 2.6 0.0 0.7 0.0 0.2 0.1 0.0 0.4 0.8 0.4 0.4 1.4 0.0 3.2 0.8 3.3 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.4 0.0 0.1 0.1 0.9 0.4 0.1 0.1 1.4 0.1 0.1 0.0 0.2 0.2 1.0 0.1 0.2 0.3 0.5 0.2 0.1 0.3 0.2 0.2 0.2 0.3 0.0 0.2 0.0 0.1 0.0 0.1 0.4 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.3 2.9 0.0 0.0 0.0 0.0 0.1 1.3 0.9 9.0 3.6 1.7 3.5 1.3 0.2 0.7 0.0 1.6 1.0 1.7 0.0 1.3 1.6 9.7 1.8 2.8 0.4 6.8 1.2 3.5 1.7 14.4 0.0 1.1 0.0 0.0 0.4 4.5 0.1 1.9 0.4 53.3 0.8 0.4 1.5 0.0 0.0 0.7 1.3 2.3 2.3 2.0 1.2 11.4 0.9 0.4 3.1 1.0 5.0 0.8 1.5 2.0 1.9 10.7 288.4 1.5 6.3 1.8 0.0 0.1 0.0 0.0 0.0 0.2 0.7 0.0 1.2 8.1 2.3 0.2 1.9 0.6 0.8 0.0 0.5 2.0 1.5 1.2 1.2 1.3 5.2 4.0 1.1 0.2 1.1 C18orf21 "HsT3108, PNAS-124, PNAS-131" ENSG00000141428 "Chromosome 18 open reading frame 21" Q32NC0 18 35972625-35979286 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 145.2;Late spermatids: 76.3;Spermatocytes: 124.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065505, HPA067322" Uncertain Approved "Nucleoli,Plasma membrane" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoli, Plasma membrane" "HPA065505: AB_2685498, HPA067322: AB_2685822" "unprognostic (7.31e-2)" "unprognostic (2.14e-3)" "unprognostic (9.88e-2)" "unprognostic (8.66e-3)" "unprognostic (2.04e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (1.38e-6)" "unprognostic (2.53e-3)" "unprognostic (1.83e-2)" "prognostic favorable (1.81e-6)" "unprognostic (2.88e-2)" "unprognostic (1.24e-1)" "unprognostic (1.16e-1)" "unprognostic (1.21e-2)" "unprognostic (5.15e-3)" "unprognostic (2.35e-3)" "unprognostic (5.97e-2)" 16.4 18.2 15.2 12.8 15.7 71.9 20.5 18.6 19.7 13.6 14.2 15.1 16.2 15.3 18.4 14.7 14.9 12.3 18.3 15.4 15.2 15.1 16.9 12.2 21.8 15.0 15.0 17.0 23.2 17.9 12.9 14.6 15.0 14.4 13.1 19.2 19.3 12.9 34.1 16.3 15.2 13.0 15.6 18.1 19.8 35.8 15.4 21.9 14.0 26.4 18.8 16.3 12.3 16.5 24.9 17.2 35.3 27.0 25.4 36.2 25.9 34.3 34.9 42.3 44.7 15.8 17.8 22.4 33.7 27.4 26.9 26.2 28.2 28.8 45.7 33.4 30.4 22.5 21.2 35.5 35.3 65.4 26.3 37.9 46.7 38.2 39.3 36.8 37.0 30.6 39.7 34.0 29.4 29.5 42.4 48.0 30.4 11.6 18.9 28.0 30.7 43.0 29.2 29.5 25.5 36.0 25.4 18.8 58.3 32.7 28.2 31.2 24.3 43.3 19.1 15.8 31.0 43.2 41.4 46.0 21.4 37.3 22.1 97.5 28.8 34.2 24.5 30.7 24.2 34.7 25.9 23.2 27.1 30.9 19.8 25.9 28.0 28.8 30.0 26.6 41.5 19.8 15.2 15.7 18.6 19.7 15.4 15.2 15.0 15.0 15.0 15.6 15.4 16.5 9.6 19.2 6.1 3.9 13.7 11.9 8.9 17.4 18.2 9.6 13.1 16.5 12.7 10.0 12.1 1.8 6.2 19.0 23.0 10.4 11.7 20.2 145.2 13.7 14.7 10.8 7.2 12.4 5.5 28.8 32.0 12.4 8.6 14.4 14.0 12.9 10.0 9.6 21.3 8.4 6.0 12.9 16.2 20.1 10.3 76.3 22.4 14.4 12.4 5.6 24.4 13.1 20.6 4.5 5.1 20.0 14.0 17.0 13.5 11.7 17.8 20.1 5.1 12.1 0.0 14.1 11.3 124.0 35.9 12.8 12.4 13.1 13.6 17.3 15.9 9.3 C18orf54 "LAS2, MGC33382" ENSG00000166845 "Chromosome 18 open reading frame 54" Q8IYD9 18 54357906-54385218 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 17.3" "Cell type enhanced" "Detected in many" "Early spermatids: 100.0;Extravillous trophoblasts: 24.0;Late spermatids: 29.7;Oligodendrocytes: 23.0;Spermatocytes: 38.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.8" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040704 Approved Nucleoplasm "Secreted in male reproductive system" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "HPA040704: AB_10959454" "unprognostic (2.96e-1)" "unprognostic (5.58e-2)" "unprognostic (5.29e-2)" "unprognostic (8.63e-3)" "unprognostic (2.40e-1)" "unprognostic (1.05e-1)" "unprognostic (5.60e-6)" "unprognostic (1.11e-2)" "unprognostic (7.85e-3)" "unprognostic (2.55e-2)" "unprognostic (5.91e-3)" "unprognostic (1.13e-2)" "unprognostic (3.06e-5)" "unprognostic (2.29e-1)" "unprognostic (4.21e-1)" "unprognostic (1.28e-2)" "unprognostic (7.05e-2)" 2.1 0.6 1.7 2.3 3.5 1.3 1.1 2.6 2.4 1.9 0.6 1.4 0.8 2.3 0.4 1.0 0.9 1.1 0.9 1.5 2.4 0.8 0.4 1.3 3.0 3.4 2.7 1.4 0.2 0.6 0.2 3.1 3.3 0.6 1.3 1.2 0.4 0.8 0.3 1.0 0.8 1.8 2.3 1.7 0.8 17.3 2.6 3.5 0.9 1.2 2.7 1.0 1.0 5.0 10.2 6.6 22.8 11.7 5.8 10.0 8.2 16.0 6.8 15.5 19.6 4.4 5.2 6.9 4.3 5.6 6.4 9.7 16.9 9.3 20.1 26.5 5.2 7.8 7.2 6.1 1.3 9.4 8.0 3.4 1.8 20.9 10.6 6.7 21.6 9.6 7.8 15.6 22.6 3.8 9.7 4.7 12.5 1.6 11.2 7.7 18.3 5.3 7.1 6.9 14.4 7.8 7.0 2.6 4.2 11.7 4.7 6.8 17.5 32.0 13.3 5.3 8.8 9.8 11.8 10.6 8.1 14.5 22.4 0.5 0.2 0.0 0.4 0.3 0.3 0.3 0.3 0.2 0.2 0.4 0.3 0.3 0.0 0.2 1.8 0.1 0.7 0.2 1.7 3.5 2.6 2.4 1.5 2.4 3.4 2.7 3.3 2.3 2.6 5.0 3.9 0.0 0.6 1.6 1.1 0.4 0.7 0.8 0.0 2.2 0.9 0.9 1.5 0.0 0.2 1.8 0.0 0.9 2.3 0.6 0.0 0.2 100.0 1.4 2.3 3.2 0.0 11.2 0.6 0.2 24.0 2.9 0.5 0.8 0.0 14.2 3.6 0.3 2.5 0.0 0.7 0.4 0.0 3.1 2.1 29.7 1.5 1.7 1.8 3.7 1.3 2.4 3.1 4.5 23.0 0.4 0.9 0.7 1.9 0.5 0.2 0.3 0.3 0.9 0.0 2.1 3.0 38.4 14.5 0.8 0.4 2.1 1.2 0.9 1.7 0.8 C1orf100 ENSG00000173728 "Chromosome 1 open reading frame 100" Q5SVJ3 1 244352635-244389663 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 63 "testis: 35.0" "Group enriched" "Detected in some" 151 "Early spermatids: 1207.7;Late spermatids: 851.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 41 "K-562: 5.9" "Not detected" "Not detected" "HPA031179, HPA031180" Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 1: K-562 - Erythropoiesis" "Cluster 34: Spermatids - Unknown function" Nucleoplasm "Nuclear bodies, Cytosol" "HPA031179: AB_10599995, HPA031180: AB_10599026" "unprognostic (9.84e-2)" "unprognostic (2.14e-3)" "unprognostic (3.37e-2)" "unprognostic (9.07e-2)" "unprognostic (6.63e-2)" "unprognostic (1.49e-2)" "unprognostic (5.45e-3)" "unprognostic (2.17e-2)" "unprognostic (4.00e-2)" "unprognostic (3.44e-1)" "unprognostic (9.67e-5)" "unprognostic (1.85e-2)" "unprognostic (2.08e-3)" "unprognostic (2.53e-2)" "unprognostic (1.79e-1)" "unprognostic (2.85e-1)" "unprognostic (1.27e-4)" 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 35.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1207.7 0.0 0.0 0.2 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 851.9 5.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.8 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 C1orf112 FLJ10706 ENSG00000000460 "Chromosome 1 open reading frame 112" Q9NSG2 1 169662007-169854080 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 13.5" "Cell type enhanced" "Detected in many" "Microglial cells: 30.0;Spermatocytes: 37.1;Spermatogonia: 20.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA023778, HPA024451" Uncertain Approved Mitochondria NA NA "Cluster 15: NK-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Mitochondria "HPA023778: AB_1848665, HPA024451: AB_1848667" "unprognostic (4.97e-2)" "unprognostic (1.46e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (9.56e-5)" "unprognostic (1.33e-1)" "unprognostic (9.40e-2)" "unprognostic (2.50e-3)" "unprognostic (2.09e-1)" "unprognostic (9.11e-3)" "unprognostic (8.79e-2)" "unprognostic (3.47e-3)" "unprognostic (5.97e-2)" "unprognostic (1.65e-8)" "unprognostic (1.76e-1)" "unprognostic (2.81e-2)" "unprognostic (6.17e-2)" "unprognostic (2.63e-1)" 1.8 1.2 0.6 3.3 0.9 9.0 2.9 1.7 0.8 2.3 0.5 2.6 1.2 2.9 1.0 2.0 1.5 1.4 1.0 0.5 0.4 1.1 2.6 1.7 6.3 1.0 0.6 2.2 1.5 13.5 1.0 3.4 0.8 1.8 4.1 5.4 1.5 2.0 0.9 2.4 1.8 2.7 0.7 2.8 1.9 10.3 0.9 11.6 1.7 1.5 7.9 3.1 1.7 1.5 32.7 17.5 21.9 11.3 3.5 4.8 32.2 21.1 10.7 30.0 30.6 19.1 27.7 29.0 9.3 7.0 10.7 26.0 27.6 14.7 34.3 16.9 16.5 27.1 23.0 14.1 1.2 35.8 11.3 1.5 1.9 22.5 5.3 3.5 12.8 16.8 44.9 48.0 24.8 7.9 31.5 10.3 28.8 22.9 12.1 23.3 24.7 19.5 4.0 16.1 16.2 16.9 13.4 22.1 6.9 20.6 21.0 18.3 9.5 24.1 19.1 17.8 28.9 12.9 20.9 30.6 9.0 26.4 24.1 2.2 0.8 1.0 0.6 1.9 0.4 1.4 0.6 0.6 1.2 1.4 0.3 0.5 0.1 2.1 2.3 0.4 0.7 0.6 0.6 0.9 1.7 0.8 0.5 0.4 1.0 0.6 0.8 0.7 0.9 1.5 1.2 0.0 3.3 4.2 4.0 1.8 2.7 2.6 1.2 4.1 1.7 1.8 0.5 0.0 1.5 0.0 6.2 9.1 1.6 1.9 0.0 2.7 8.7 0.9 2.1 2.2 0.0 3.4 9.9 3.4 9.1 2.5 2.6 1.2 4.5 9.8 2.9 3.8 6.2 1.7 9.6 1.2 6.1 3.5 2.1 4.1 2.1 3.0 3.6 30.0 1.3 2.4 0.0 13.0 13.2 3.0 0.3 3.8 5.5 1.0 0.8 0.7 2.0 6.6 6.6 1.4 2.6 37.1 20.3 2.8 1.0 3.8 3.3 2.2 2.6 2.4 C1orf116 "FLJ36507, MGC2742, MGC4309, SARG" ENSG00000182795 "Chromosome 1 open reading frame 116" Q9BW04 1 207018522-207032756 "Predicted intracellular proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 102.3;lung: 72.9;stomach 1: 58.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 176.3;Alveolar cells type 2: 99.4;Club cells: 68.5;Urothelial cells: 128.1" "Cancer enhanced" "Detected in many" "prostate cancer: 65.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 57.7;CAPAN-2: 99.5;HaCaT: 123.1;HBEC3-KT: 118.6;hTCEpi: 61.4;RPTEC TERT1: 56.4" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA011888, HPA011889" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA 180000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cytosol" "HPA011888: AB_1853872, HPA011889: AB_1853873" "unprognostic (1.52e-2)" "unprognostic (1.17e-1)" "unprognostic (8.95e-2)" "unprognostic (1.68e-1)" "unprognostic (2.35e-1)" "unprognostic (5.78e-2)" "unprognostic (3.27e-1)" "unprognostic (5.19e-2)" "unprognostic (8.07e-2)" "unprognostic (4.18e-2)" "unprognostic (2.87e-3)" "unprognostic (7.09e-3)" "prognostic favorable (1.01e-5)" "unprognostic (5.17e-1)" "unprognostic (2.48e-1)" "unprognostic (7.57e-3)" "unprognostic (1.19e-1)" 0.2 0.4 0.0 1.6 0.0 0.8 10.4 0.0 0.1 15.1 0.0 8.9 24.5 0.2 0.7 102.3 2.6 9.8 0.5 0.0 0.0 8.4 0.5 72.9 0.0 0.0 0.0 0.1 12.9 0.0 0.3 0.2 0.0 50.9 8.4 0.0 29.4 1.9 0.5 37.7 20.3 0.3 0.0 0.2 58.7 0.9 0.0 0.3 4.2 0.5 16.1 20.6 31.2 0.0 57.7 7.7 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 5.1 99.5 0.0 6.5 0.0 0.0 123.1 0.0 118.6 0.0 0.1 0.0 10.6 1.0 1.6 0.0 0.0 0.6 0.0 61.4 0.0 34.2 0.0 0.0 0.2 6.9 0.1 0.0 0.1 0.1 0.2 0.1 37.3 3.3 0.0 0.0 0.2 56.4 15.1 0.1 0.3 1.1 11.1 0.5 0.4 0.2 0.2 0.0 0.0 0.3 0.1 0.3 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 176.3 99.4 0.0 0.3 20.8 53.0 26.8 10.8 0.0 5.4 7.2 49.9 30.0 68.5 11.0 0.0 0.1 0.1 40.7 15.6 24.3 5.7 6.7 1.4 1.7 10.7 0.0 0.1 24.4 0.0 1.6 50.4 14.9 6.3 0.0 0.0 0.0 0.2 0.0 0.1 19.8 12.2 0.0 1.2 5.5 0.3 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 60.7 35.3 0.0 0.3 56.5 31.8 0.3 41.0 0.0 0.0 0.0 2.8 0.1 0.0 24.3 23.3 0.0 0.3 0.1 8.9 128.1 C1orf122 FLJ45459 ENSG00000197982 "Chromosome 1 open reading frame 122" Q6ZSJ8 1 37806979-37809454 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" "unprognostic (7.83e-2)" "unprognostic (4.07e-3)" "unprognostic (1.46e-1)" "unprognostic (7.79e-3)" "unprognostic (1.66e-1)" "unprognostic (1.39e-1)" "unprognostic (1.45e-3)" "unprognostic (7.12e-2)" "unprognostic (1.69e-1)" "unprognostic (4.44e-2)" "unprognostic (2.81e-3)" "unprognostic (3.89e-1)" "unprognostic (3.58e-2)" "unprognostic (9.64e-2)" "unprognostic (1.65e-1)" "unprognostic (1.90e-2)" "prognostic unfavorable (4.81e-4)" 48.1 85.5 80.5 10.3 87.3 7.6 44.2 86.7 92.3 39.0 77.0 54.3 11.3 40.4 20.2 50.9 36.4 7.5 76.2 74.7 76.4 74.3 82.5 34.8 7.0 90.8 85.3 31.8 63.0 19.7 101.8 10.3 82.7 60.1 8.2 24.9 40.5 18.1 61.1 37.2 33.0 11.2 87.4 32.4 55.5 39.7 87.7 6.7 42.9 21.6 7.1 45.3 37.3 94.9 38.2 19.7 21.3 25.6 35.3 40.3 84.8 43.5 23.5 29.6 25.8 33.7 37.0 20.7 91.5 27.5 22.1 33.9 14.4 30.1 16.8 39.0 48.1 13.9 23.8 20.8 49.9 18.5 24.7 48.9 65.3 23.8 27.5 33.0 20.5 17.6 35.1 21.1 27.4 36.2 19.4 32.4 57.6 30.7 50.0 29.2 20.9 43.5 30.9 19.4 39.3 63.8 31.5 30.8 38.8 37.6 40.3 11.8 24.9 37.1 33.4 20.9 40.8 49.4 26.7 24.8 33.5 20.5 29.2 1.4 4.9 5.8 3.7 5.8 1.7 1.2 2.5 2.2 3.6 2.9 1.5 2.4 3.0 3.1 5.6 2.5 2.7 2.9 80.5 87.3 86.7 92.3 74.7 76.4 90.8 85.3 82.7 87.4 87.7 94.9 57.4 3.2 14.0 37.9 38.5 55.4 95.5 45.9 51.2 146.1 101.4 95.4 83.3 60.1 30.8 82.8 41.7 84.5 47.9 105.4 266.1 59.6 11.5 62.5 60.5 57.5 113.6 10.8 19.0 109.9 132.4 80.4 31.1 124.8 34.3 67.9 61.8 127.3 146.3 69.0 23.2 73.7 95.6 52.0 56.5 30.2 49.0 80.1 83.6 9.4 94.3 246.5 41.2 15.1 108.2 71.1 88.0 73.7 51.6 201.6 64.6 274.4 25.2 145.0 32.9 55.2 99.8 24.2 19.6 50.2 60.1 106.7 39.2 126.0 57.8 147.8 C1orf94 MGC15882 ENSG00000142698 "Chromosome 1 open reading frame 94" Q6P1W5 1 34166883-34219131 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 20 "testis: 19.6" "Group enriched" "Detected in some" 28 "Early spermatids: 65.2;Late spermatids: 27.9;Spermatocytes: 34.6" "Cancer enriched" "Detected in single" 10 "glioma: 1.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "NTERA-2: 17.0;U-87 MG: 48.1" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA045805 Approved Nucleoplasm,Cytosol NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol Nucleoplasm "HPA045805: AB_10969626" "unprognostic (1.17e-1)" "unprognostic (1.38e-1)" "unprognostic (9.77e-2)" "unprognostic (4.09e-2)" "unprognostic (1.65e-2)" "unprognostic (2.31e-1)" 0.0 0.1 0.5 0.0 0.3 0.0 0.0 0.4 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 19.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.0 0.0 1.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 48.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.4 0.5 0.4 0.8 0.5 0.5 0.5 0.8 0.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 65.2 0.0 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 27.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.4 0.8 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 34.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 C1QA ENSG00000173372 "Complement C1q A chain" P02745 1 22636628-22639678 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement pathway, Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 1092.6" "Group enriched" "Detected in many" 9 "Hofbauer cells: 1663.2;Kupffer cells: 5007.4;Macrophages: 1874.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 39 "intermediate monocyte: 226.1;non-classical monocyte: 181.7" "Lineage enriched" "Detected in many" 60 "monocytes: 226.1" "Cell line enhanced" "Detected in some" "HMC-1: 2.3;NB-4: 1.4;RPMI-8226: 7.1;SCLC-21H: 3.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002350, CAB009823" Supported "Secreted to blood" NA NA 2700000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" "CAB009823: AB_2228238, HPA002350: AB_1078552" "unprognostic (1.97e-1)" "unprognostic (1.14e-2)" "unprognostic (1.98e-3)" "unprognostic (3.07e-2)" "unprognostic (6.10e-2)" "unprognostic (2.60e-1)" "unprognostic (1.16e-1)" "unprognostic (2.13e-1)" "unprognostic (1.67e-2)" "unprognostic (1.99e-1)" "unprognostic (4.42e-2)" "unprognostic (1.86e-1)" "prognostic unfavorable (1.58e-6)" "unprognostic (1.54e-1)" "unprognostic (2.11e-3)" "unprognostic (2.75e-2)" "unprognostic (7.30e-2)" 375.1 235.6 86.6 134.0 85.6 53.9 95.9 85.8 135.3 75.8 120.0 142.8 172.3 43.1 26.0 58.3 75.6 172.4 74.8 82.9 93.7 56.2 208.8 404.3 532.3 126.7 110.1 37.5 34.3 26.2 46.3 256.3 110.3 47.1 120.2 4.1 48.1 54.6 14.8 21.8 190.1 195.0 107.5 1092.6 90.8 38.2 109.4 100.3 36.5 49.3 68.0 257.5 30.4 131.6 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.4 0.3 0.0 0.0 0.5 0.2 7.1 0.0 0.0 3.0 0.9 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.1 0.4 0.1 0.8 0.0 0.0 0.1 0.1 0.0 0.1 5.2 0.1 0.1 226.1 0.0 0.0 0.1 0.1 3.7 0.0 0.0 0.0 0.5 0.3 181.7 0.0 0.0 9.7 86.6 85.6 85.8 135.3 82.9 93.7 126.7 110.1 110.3 107.5 109.4 131.6 17.4 35.3 55.8 0.0 19.0 18.4 2.3 0.0 2.2 0.4 5.1 24.6 8.9 37.1 18.0 0.0 0.0 8.7 2.7 0.5 0.0 0.0 4.5 0.2 0.5 46.0 1.8 41.0 0.0 0.2 11.3 9.6 0.0 0.2 21.5 0.2 76.1 26.2 1663.2 0.0 0.0 0.1 0.0 5007.4 291.4 9.9 13.1 1874.2 26.6 20.6 16.7 0.3 0.0 0.0 0.1 0.0 0.1 0.4 2.8 1.3 0.1 1.1 15.3 0.8 78.9 7.4 4.6 0.7 2.1 4.2 16.8 18.2 11.8 0.0 0.2 1.3 C1QB ENSG00000173369 "Complement C1q B chain" 1 22652762-22661637 "Human disease related genes, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "lung: 546.4;lymphoid tissue: 990.2" "Group enriched" "Detected in many" 28 "Hofbauer cells: 1451.0;Kupffer cells: 4559.7;Macrophages: 1747.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 71 "intermediate monocyte: 140.6;non-classical monocyte: 101.2" "Lineage enriched" "Detected in many" 85 "monocytes: 140.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052116 Approved "Secreted to blood" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 4: Macrophages - Innate immune response" "HPA052116: AB_2681735" "unprognostic (1.42e-1)" "unprognostic (3.36e-2)" "unprognostic (5.61e-3)" "unprognostic (8.20e-2)" "unprognostic (5.93e-2)" "unprognostic (4.09e-1)" "unprognostic (1.25e-1)" "unprognostic (2.35e-1)" "unprognostic (2.87e-2)" "unprognostic (2.21e-1)" "unprognostic (2.63e-2)" "unprognostic (1.57e-1)" "prognostic unfavorable (9.58e-6)" "unprognostic (4.14e-2)" "unprognostic (7.76e-3)" "unprognostic (4.83e-2)" "unprognostic (2.35e-2)" 439.2 229.0 95.8 149.4 94.2 53.5 87.1 97.2 148.7 65.4 132.6 162.0 186.0 27.7 26.4 63.0 50.5 194.9 62.6 89.8 107.7 18.3 243.4 546.4 514.6 161.0 143.3 39.6 40.0 28.5 1.8 249.2 138.4 28.0 146.0 7.8 44.9 51.2 5.3 6.1 186.1 261.4 138.2 990.2 88.0 39.9 142.2 72.0 23.6 38.6 58.4 255.8 1.1 185.8 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.8 0.4 0.0 0.0 0.5 0.3 0.6 0.0 0.0 0.5 0.8 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.8 0.0 0.1 0.1 0.0 0.2 0.0 1.7 0.0 0.0 140.6 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.4 0.8 101.2 0.0 0.0 5.3 95.8 94.2 97.2 148.7 89.8 107.7 161.0 143.3 138.4 138.2 142.2 185.8 13.8 12.8 22.1 0.0 17.1 6.2 2.1 0.0 1.8 1.2 4.9 23.1 5.5 24.3 10.5 3.7 0.0 6.6 2.7 0.6 0.0 0.0 3.3 0.1 0.2 65.9 0.0 32.8 0.1 0.0 9.6 5.9 0.0 0.1 11.4 0.1 52.1 26.0 1451.0 0.0 0.1 0.0 0.0 4559.7 92.1 7.8 8.4 1747.2 0.0 34.7 5.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 2.3 1.0 0.3 1.1 3.6 3.9 59.2 4.0 3.2 0.4 0.9 5.7 4.5 9.6 6.1 0.2 0.0 1.5 C1QC C1QG ENSG00000159189 "Complement C1q C chain" P02747 1 22643633-22648110 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 950.7" "Group enriched" "Detected in many" 7 "Hofbauer cells: 1356.5;Kupffer cells: 2134.6;Macrophages: 1040.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "intermediate monocyte: 57.2" "Lineage enriched" "Detected in single" 541 "monocytes: 57.2" "Cell line enhanced" "Detected in some" "NB-4: 1.0;RPMI-8226: 2.6;U-266/70: 1.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001471, CAB009828" Supported "Secreted to blood" NA NA 513000000 2100000000 "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" "CAB009828: AB_2067541, HPA001471: AB_1078553" "unprognostic (2.97e-1)" "unprognostic (6.80e-2)" "unprognostic (2.40e-2)" "unprognostic (1.84e-1)" "unprognostic (7.40e-2)" "unprognostic (2.38e-1)" "unprognostic (1.98e-1)" "unprognostic (1.40e-1)" "unprognostic (1.66e-2)" "unprognostic (7.44e-2)" "unprognostic (2.75e-2)" "unprognostic (1.32e-1)" "prognostic unfavorable (1.17e-5)" "unprognostic (1.06e-1)" "unprognostic (1.63e-3)" "unprognostic (2.21e-2)" "unprognostic (3.73e-2)" 285.2 196.0 60.1 159.7 58.6 43.5 70.5 64.8 97.1 51.9 90.6 133.2 179.9 36.3 13.5 55.3 67.4 155.4 58.6 54.9 75.5 41.2 169.6 290.8 370.2 124.7 105.4 32.1 37.5 22.1 39.6 204.9 105.0 37.8 91.3 3.9 51.6 44.5 12.9 18.3 195.7 164.7 100.4 950.7 94.8 33.9 106.0 75.7 29.2 31.8 50.7 191.8 24.6 159.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 1.0 0.2 0.0 0.0 0.6 0.2 2.6 0.0 0.0 0.4 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.1 1.0 0.0 0.1 0.1 0.1 0.0 0.0 1.3 0.0 0.0 57.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 10.4 0.0 0.0 1.2 60.1 58.6 64.8 97.1 54.9 75.5 124.7 105.4 105.0 100.4 106.0 159.3 13.4 6.4 5.2 0.3 13.7 8.9 1.1 0.0 2.8 0.6 4.9 24.5 1.6 15.7 3.1 0.0 0.0 5.8 2.3 0.4 0.0 0.0 3.2 0.0 0.1 34.5 0.0 27.2 0.0 0.2 9.5 4.4 0.0 0.1 5.1 0.1 25.4 6.6 1356.5 0.0 0.1 0.1 0.0 2134.6 202.4 3.6 6.2 1040.7 7.2 29.0 23.6 0.4 0.0 0.0 0.0 0.0 1.1 1.2 0.9 0.4 0.0 0.4 0.7 0.6 46.0 2.5 1.8 0.4 0.8 3.3 6.5 9.9 3.5 0.0 0.0 0.7 C1QL4 "C1QTNF11, CTRP11" ENSG00000186897 "Complement C1q like 4" Q86Z23 12 49332409-49337188 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 7.8;testis: 4.2" "Group enriched" "Detected in some" 8 "Early spermatids: 37.2;Horizontal cells: 25.2;Late spermatids: 84.5" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "midbrain: 7.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 35.3;HAP1: 5.5;PC-3: 5.9;U-2 OS: 9.0" "Region enhanced" "Detected in some" "midbrain: 6.2" "Region enhanced" "Detected in some" "pons: 7.6" "Secreted in brain" NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (1.97e-2)" "unprognostic (2.77e-2)" "unprognostic (4.87e-2)" "unprognostic (7.37e-2)" "unprognostic (4.48e-1)" "unprognostic (1.86e-2)" "unprognostic (2.49e-3)" "unprognostic (8.64e-3)" "unprognostic (2.89e-1)" "unprognostic (5.11e-3)" "unprognostic (7.62e-2)" "unprognostic (5.03e-2)" "prognostic unfavorable (3.03e-5)" "unprognostic (9.73e-2)" "unprognostic (2.85e-2)" "unprognostic (9.40e-2)" "unprognostic (3.72e-2)" 0.2 0.0 0.5 0.0 1.5 0.0 0.2 0.3 0.5 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.5 0.9 0.0 0.0 0.0 0.8 7.8 0.0 0.0 0.1 0.2 0.0 3.9 0.1 0.0 0.9 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 4.2 0.5 0.0 0.9 0.0 0.0 0.0 1.1 0.8 0.4 1.4 0.4 35.3 0.0 0.0 0.1 0.0 0.1 0.5 1.9 0.9 0.1 0.4 2.0 0.0 2.0 0.1 5.5 0.0 0.6 0.1 2.5 0.0 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.6 0.1 0.4 0.0 1.2 0.2 0.0 0.0 0.9 0.0 0.0 0.7 0.1 5.9 0.2 0.2 0.0 0.1 0.0 0.0 3.0 0.0 0.3 1.6 0.1 0.7 0.2 0.0 0.5 9.0 0.1 0.5 0.3 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.5 0.3 0.5 0.2 1.5 0.8 7.8 3.9 0.1 0.5 0.8 0.0 0.0 0.0 0.3 0.0 0.1 0.2 0.0 0.0 0.0 0.3 0.4 1.1 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 37.2 0.2 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 25.2 0.0 0.0 0.0 0.0 0.3 84.5 0.9 0.0 3.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 1.3 0.0 0.0 0.3 5.6 5.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 C20orf173 dJ477O4.4 ENSG00000125975 "Chromosome 20 open reading frame 173" Q96LM9 20 35523186-35529652 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 45 "testis: 35.5" "Group enriched" "Detected in some" 76 "Early spermatids: 473.3;Late spermatids: 156.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA076859 Uncertain "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "Vesicles, Plasma membrane" "HPA076859: " "unprognostic (1.90e-1)" "unprognostic (1.03e-1)" 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 35.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 473.3 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 156.5 4.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 C2CD6 "ALS2CR11, FLJ25351" ENSG00000155754 "C2 calcium dependent domain containing 6" Q53TS8 2 201487421-201619178 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 39.9" "Cell type enriched" "Detected in some" 21 "Theca cells: 41.0" "Cancer enhanced" "Detected in single" "testis cancer: 0.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 1.9;HSkMC: 2.0;hTEC/SVTERT24-B: 2.0;SCLC-21H: 2.3;THP-1: 2.0;U-2197: 7.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 18: U-2197 - ECM organization" "Cluster 52: Non-specific - Transcription" "unprognostic (2.64e-1)" "unprognostic (1.14e-1)" "unprognostic (8.77e-3)" "unprognostic (7.13e-6)" "unprognostic (1.33e-1)" "unprognostic (4.38e-2)" "unprognostic (2.16e-1)" "unprognostic (4.81e-2)" "unprognostic (3.15e-2)" "unprognostic (6.53e-2)" "unprognostic (3.43e-1)" "unprognostic (2.10e-1)" "unprognostic (5.13e-10)" "unprognostic (1.95e-1)" "unprognostic (6.35e-2)" "unprognostic (2.00e-1)" "unprognostic (2.18e-1)" 0.6 0.7 1.5 0.0 2.2 0.0 0.3 2.3 1.2 0.1 0.8 0.1 0.1 0.2 0.1 0.2 0.1 0.4 1.2 0.5 2.2 0.1 0.1 0.3 0.2 5.5 2.6 0.7 0.0 0.0 0.7 0.1 4.5 0.3 0.0 0.9 0.1 0.1 0.1 0.1 0.1 0.2 4.3 0.1 0.0 39.9 2.3 0.0 0.1 0.0 0.0 0.1 0.1 6.6 0.0 0.0 0.0 0.0 0.2 1.9 0.3 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 2.0 0.0 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.1 0.2 0.1 0.0 2.0 0.0 0.0 0.5 7.6 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.5 2.2 2.3 1.2 0.5 2.2 5.5 2.6 4.5 4.3 2.3 6.6 0.3 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.6 0.0 0.0 0.1 0.1 0.0 1.9 0.0 0.0 0.3 1.4 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 1.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 41.0 0.0 0.0 C2orf76 "AIM29, LOC130355, MGC104437" ENSG00000186132 "Chromosome 2 open reading frame 76" Q3KRA6 2 119302225-119366834 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 78.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044977, HPA055362" Approved Approved "Endoplasmic reticulum" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 39: Non-specific - Basic cellular processes" "Endoplasmic reticulum" "HPA044977: AB_10961918, HPA055362: AB_2682794" "unprognostic (4.29e-1)" "unprognostic (2.07e-1)" "unprognostic (5.40e-3)" "unprognostic (1.04e-1)" "unprognostic (1.16e-2)" "unprognostic (2.20e-2)" "unprognostic (1.47e-3)" "unprognostic (5.51e-2)" "unprognostic (3.26e-3)" "unprognostic (1.16e-1)" "unprognostic (4.77e-2)" "unprognostic (1.14e-1)" "prognostic unfavorable (2.16e-8)" "unprognostic (3.42e-2)" "unprognostic (2.91e-2)" "unprognostic (7.55e-2)" "unprognostic (9.19e-2)" 20.2 19.7 23.2 10.2 23.3 10.0 22.4 23.8 29.5 13.0 21.3 12.3 6.9 17.1 43.4 16.2 20.5 12.6 16.1 22.2 23.5 19.9 14.1 9.9 15.2 24.3 23.2 17.8 15.7 20.6 10.7 11.3 24.4 16.0 11.7 9.4 16.0 15.4 10.3 20.6 7.6 16.7 24.2 10.9 11.3 19.3 23.0 13.5 20.5 14.5 14.0 13.9 10.9 26.6 17.0 15.7 22.4 14.3 31.7 38.3 12.8 23.4 16.7 15.0 16.3 10.1 11.3 20.7 40.6 24.7 17.4 7.8 10.1 14.9 15.0 17.7 33.5 39.1 11.7 13.5 21.8 15.0 24.6 20.4 25.3 21.3 13.8 19.3 21.7 15.7 12.6 19.6 22.5 25.7 15.7 28.5 12.4 13.3 12.4 9.6 4.7 29.1 33.9 18.0 14.8 16.7 17.0 24.1 33.7 21.0 13.2 52.5 20.3 17.4 13.5 14.6 12.7 12.8 22.5 22.1 17.5 11.1 20.0 29.1 20.9 21.9 19.9 20.2 18.0 20.0 15.2 18.3 21.3 14.7 13.8 19.3 37.2 32.5 12.7 20.1 16.8 11.9 23.2 23.3 23.8 29.5 22.2 23.5 24.3 23.2 24.4 24.2 23.0 26.6 30.3 6.4 11.4 22.5 11.1 25.0 17.2 47.7 17.1 3.3 18.5 19.7 18.5 12.8 24.4 14.7 0.0 26.4 15.2 7.1 78.2 14.7 11.7 27.6 15.4 20.4 10.9 16.4 12.4 17.8 32.4 20.7 9.7 19.7 22.2 8.4 15.0 11.6 26.7 1.7 8.6 11.2 22.4 15.0 23.4 7.7 19.3 13.8 44.4 12.2 20.6 19.8 26.8 14.6 25.2 14.0 9.2 17.0 8.9 11.8 12.2 47.0 42.8 4.6 6.6 13.8 18.8 38.8 22.4 18.8 35.7 20.7 15.3 11.4 10.0 13.0 C3AR1 "AZ3B, C3AR" ENSG00000171860 "Complement C3a receptor 1" Q16581 12 8056844-8066359 "G-protein coupled receptors, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 40.1" "Cell type enhanced" "Detected in some" "granulocytes: 36.8;Hofbauer cells: 161.5;Kupffer cells: 139.7;Macrophages: 105.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 898.6;eosinophil: 450.8;intermediate monocyte: 273.6;non-classical monocyte: 371.3" "Group enriched" "Detected in many" 20 "granulocytes: 898.6;monocytes: 371.3" "Cell line enriched" "Detected in some" 9 "HMC-1: 148.0" "Low region specificity" "Detected in many" CAB009405 Enhanced NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "CAB009405: AB_2066739" "unprognostic (1.11e-2)" "unprognostic (5.67e-2)" "unprognostic (5.06e-2)" "unprognostic (4.14e-2)" "unprognostic (6.60e-2)" "unprognostic (1.50e-1)" "unprognostic (4.81e-2)" "unprognostic (2.78e-1)" "unprognostic (6.10e-2)" "unprognostic (8.04e-2)" "unprognostic (1.59e-1)" "unprognostic (3.50e-2)" "unprognostic (8.22e-2)" "unprognostic (4.96e-2)" "unprognostic (9.24e-3)" "unprognostic (2.09e-2)" "unprognostic (8.16e-2)" 18.0 10.6 3.8 40.1 4.0 22.9 6.7 4.7 5.7 6.8 4.4 7.4 6.6 3.8 1.5 3.9 5.9 16.2 4.4 3.9 6.9 3.1 10.8 18.6 12.4 10.1 6.3 3.7 6.0 3.3 2.5 22.0 9.0 3.3 6.8 0.8 5.6 4.3 1.4 2.0 9.7 15.6 8.3 21.4 5.3 2.1 7.8 4.9 2.4 2.6 5.1 15.2 2.7 15.6 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 1.9 0.5 3.8 0.0 0.0 1.6 0.0 0.0 2.2 0.1 0.0 0.0 0.1 0.0 0.0 12.0 0.0 0.0 1.4 15.6 148.0 0.7 0.0 0.2 0.4 0.3 0.7 1.2 4.0 8.2 0.7 0.0 0.7 5.2 0.1 0.0 0.0 0.1 3.1 15.1 0.7 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 6.6 0.6 0.5 0.4 0.1 0.3 0.3 0.0 0.4 8.5 6.4 0.4 898.6 105.0 450.8 21.8 273.6 26.9 0.2 10.6 14.5 31.1 0.3 2.0 7.8 14.0 4.1 371.3 2.8 11.0 76.0 3.8 4.0 4.7 5.7 3.9 6.9 10.1 6.3 9.0 8.3 7.8 15.6 0.7 0.0 3.0 0.3 1.1 0.5 0.1 0.1 0.0 0.1 0.3 0.9 0.6 1.5 2.5 0.0 2.1 0.7 5.9 0.0 0.0 0.0 3.0 0.0 0.1 6.6 0.0 0.8 0.4 0.2 1.0 0.6 0.0 0.0 36.8 0.0 1.8 0.8 161.5 0.0 0.3 0.0 0.0 139.7 19.8 4.2 1.2 105.7 0.0 8.4 16.2 0.0 8.2 0.0 0.2 0.0 0.0 0.0 2.6 0.0 0.0 0.2 0.7 0.4 19.7 0.7 1.0 0.0 0.2 0.0 0.6 1.5 8.6 0.1 0.0 0.0 C3orf18 G20 ENSG00000088543 "Chromosome 3 open reading frame 18" Q9UK00 3 50558025-50571027 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 29.3;Early spermatids: 54.2;Late spermatids: 62.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "B-cells: 2.2;NK-cells: 2.0;T-cells: 6.3" "Cell line enhanced" "Detected in many" "HDLM-2: 48.8" "Group enriched" "Detected in all" 4 "cerebellum: 28.2;olfactory bulb: 27.5" "Low region specificity" "Detected in all" HPA012105 Approved Approved Cytosol No No "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 34: Spermatids - Unknown function" Cytosol "HPA012105: AB_1845717" "unprognostic (9.29e-3)" "unprognostic (1.46e-2)" "unprognostic (6.96e-2)" "unprognostic (5.00e-2)" "unprognostic (8.19e-2)" "unprognostic (4.05e-1)" "unprognostic (1.44e-1)" "unprognostic (1.05e-2)" "unprognostic (1.64e-1)" "unprognostic (1.76e-1)" "unprognostic (2.10e-3)" "unprognostic (1.29e-2)" "prognostic favorable (2.80e-9)" "unprognostic (7.65e-2)" "unprognostic (4.49e-1)" "unprognostic (2.18e-1)" "unprognostic (1.59e-1)" 6.1 8.7 23.0 2.9 23.6 0.9 5.6 30.0 24.0 10.8 25.8 11.9 1.8 10.6 4.4 3.5 9.3 3.6 33.3 22.2 25.6 9.4 4.9 3.7 3.8 23.6 24.9 12.6 6.6 27.3 12.5 2.1 23.2 9.2 2.6 28.4 7.1 9.8 36.2 3.1 5.3 9.5 22.8 5.2 10.1 19.7 25.1 3.1 9.0 26.8 3.6 9.5 6.4 22.1 1.8 2.7 3.1 0.6 10.1 9.0 1.0 11.1 17.2 9.9 7.2 0.2 2.8 2.3 2.6 15.2 9.3 0.2 0.0 4.3 5.2 48.8 0.3 5.0 6.9 0.8 5.0 0.0 6.0 8.9 0.6 9.6 0.5 7.9 1.9 7.2 1.1 2.2 5.9 0.4 0.4 1.5 3.8 1.9 12.3 1.0 0.3 2.7 0.6 0.4 3.4 16.1 2.9 0.6 0.3 3.5 3.4 1.3 0.6 9.9 7.7 18.1 1.4 2.8 2.5 0.3 14.0 5.1 0.2 0.0 0.4 0.7 5.1 0.1 6.3 2.2 4.3 4.8 0.4 1.4 5.0 6.1 0.0 2.0 0.1 0.8 2.2 2.5 23.0 23.6 30.0 24.0 22.2 25.6 23.6 24.9 23.2 22.8 25.1 22.1 1.8 0.0 1.1 8.1 2.2 1.1 1.1 0.9 1.2 10.2 1.8 2.0 29.3 0.0 1.4 1.8 8.4 0.4 1.3 0.3 3.9 2.1 54.2 1.1 2.3 2.6 1.8 0.0 5.6 1.8 0.8 4.9 1.5 0.5 0.0 3.1 2.5 2.2 1.6 1.7 8.3 0.7 0.0 1.3 0.3 62.6 4.7 1.1 0.0 3.7 8.9 12.4 3.1 3.0 3.3 0.7 0.1 4.1 1.6 0.5 0.1 3.5 1.2 17.3 13.1 5.6 5.3 2.7 2.5 0.1 0.4 0.1 3.0 2.7 0.3 0.2 C3orf49 ENSG00000163632 "Chromosome 3 open reading frame 49" Q96BT1 3 63819299-63848636 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 1.7" "Group enriched" "Detected in some" 6 "Early spermatids: 19.5;Late spermatids: 34.4" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebral cortex: 1.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 2.0;MCF7: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA053582 Uncertain Approved Vesicles,Centrosome,Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "Vesicles, Centrosome" "HPA053582: AB_2682199" "unprognostic (2.90e-1)" "unprognostic (2.63e-1)" "unprognostic (4.81e-2)" "unprognostic (1.64e-1)" "unprognostic (1.07e-1)" "unprognostic (5.27e-3)" "unprognostic (1.79e-1)" "unprognostic (2.14e-2)" "unprognostic (9.29e-3)" "unprognostic (1.72e-1)" "unprognostic (5.14e-2)" "unprognostic (9.47e-3)" "unprognostic (7.61e-3)" "unprognostic (1.02e-1)" "unprognostic (7.68e-2)" "unprognostic (5.79e-2)" "unprognostic (1.07e-1)" 0.0 0.2 0.1 0.2 0.4 0.6 0.0 1.2 1.7 0.1 0.0 0.1 0.6 0.3 0.0 0.7 0.1 0.2 0.3 0.2 0.0 0.1 0.3 0.3 0.3 0.0 0.0 0.5 0.6 0.0 0.0 0.1 0.0 0.1 0.0 1.4 0.3 0.0 1.1 0.9 0.3 0.0 0.0 0.2 0.2 1.3 0.0 0.0 0.4 0.0 0.0 0.1 0.0 1.1 0.2 0.7 0.4 0.4 0.0 0.1 0.4 0.6 0.0 0.0 0.0 0.7 0.3 1.0 0.1 0.0 0.2 0.4 0.0 0.0 0.1 0.5 0.6 0.8 2.0 0.2 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.5 0.4 0.0 1.8 0.4 0.4 0.5 0.4 0.1 0.6 0.4 0.9 0.0 0.4 0.4 0.3 0.1 0.9 0.1 0.1 0.2 0.3 0.5 0.3 0.4 0.6 0.7 0.2 0.9 0.1 0.9 1.4 0.4 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.2 0.1 0.1 0.3 0.1 0.0 0.1 0.0 0.1 0.4 1.2 1.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.0 0.2 0.1 0.5 0.0 0.0 2.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 19.5 0.2 0.2 0.1 0.0 0.0 3.9 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 3.2 0.0 0.0 0.0 0.0 34.4 0.3 0.0 0.0 1.0 0.1 0.2 0.0 1.5 1.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.1 0.0 0.3 0.2 0.3 0.3 0.0 0.0 0.3 0.0 0.1 0.0 0.3 C4orf19 FLJ11017 ENSG00000154274 "Chromosome 4 open reading frame 19" Q8IY42 4 37453925-37623495 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 36.0" "Cell type enhanced" "Detected in many" "Astrocytes: 45.4;Distal enterocytes: 61.3;Exocrine glandular cells: 51.8;Oligodendrocyte precursor cells: 46.8;Pancreatic endocrine cells: 53.6;Paneth cells: 67.2;Proximal enterocytes: 52.3;Syncytiotrophoblasts: 47.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 8.6" "Lineage enriched" "Detected in many" 5 "granulocytes: 8.6" "Group enriched" "Detected in some" 5 "OE19: 64.6;RT4: 81.0;SK-BR-3: 32.6;T-47d: 113.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043458, HPA052894" Enhanced Supported "Cell Junctions" No No "Cluster 1: Neutrophils - Mixed function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 6: T47d - Mammary gland" "Cluster 53: Intestinal epithelial cells - Unknown function" "Cell Junctions" "HPA043458: AB_10960696, HPA052894: AB_2681982" "unprognostic (8.83e-2)" "unprognostic (7.86e-2)" "unprognostic (3.00e-3)" "unprognostic (2.04e-2)" "unprognostic (2.23e-1)" "unprognostic (3.59e-3)" "unprognostic (5.55e-2)" "unprognostic (2.29e-1)" "unprognostic (6.66e-2)" "unprognostic (9.96e-2)" "unprognostic (1.35e-1)" "unprognostic (4.38e-2)" "prognostic favorable (1.49e-11)" "unprognostic (1.33e-1)" "unprognostic (1.60e-1)" "unprognostic (1.63e-3)" "unprognostic (8.19e-3)" 3.4 0.3 2.7 3.0 2.9 3.8 3.8 5.3 4.3 10.2 5.9 25.5 17.7 6.7 0.2 2.1 2.8 9.2 0.4 3.5 4.2 12.4 36.0 3.7 0.5 4.9 4.9 0.2 24.9 16.0 1.2 7.6 4.2 1.7 23.7 4.6 28.2 6.8 0.2 1.6 19.6 4.0 4.5 0.3 20.7 1.4 4.9 0.2 1.5 0.4 4.3 8.8 2.9 4.1 0.1 0.2 3.2 0.3 0.0 0.0 4.2 0.7 0.0 0.0 0.0 12.6 5.2 0.1 3.0 0.0 0.1 0.4 0.2 0.8 0.1 0.0 0.4 0.0 8.3 0.1 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.1 14.3 0.2 0.2 0.5 64.6 1.7 0.1 7.8 0.2 12.7 81.0 0.9 0.3 0.5 32.6 1.0 4.0 113.1 0.7 0.6 0.4 4.5 0.2 1.6 0.2 0.1 0.5 0.0 6.9 5.6 0.9 1.4 2.1 0.6 0.2 0.4 0.2 0.3 0.4 0.2 0.5 0.5 0.8 8.6 0.8 0.1 1.6 0.7 0.3 2.7 2.9 5.3 4.3 3.5 4.2 4.9 4.9 4.2 4.5 4.9 4.1 0.3 0.0 12.6 45.4 0.7 0.3 7.8 4.9 0.0 0.6 7.1 3.9 0.2 27.1 10.1 11.0 0.0 6.7 0.2 61.3 11.7 25.2 1.2 9.5 0.4 0.9 9.6 0.0 2.3 51.8 4.7 0.3 33.6 5.5 0.0 0.0 0.0 13.1 0.7 0.0 2.4 28.0 4.1 0.0 0.3 2.4 0.0 0.2 3.6 22.5 0.6 5.3 0.0 46.8 1.8 53.6 67.2 0.0 0.0 7.8 52.3 9.2 12.3 1.0 0.0 0.2 0.9 0.3 0.2 0.5 0.0 47.5 0.4 0.1 31.8 19.1 C5orf46 "MGC23985, SSSP1" ENSG00000178776 "Chromosome 5 open reading frame 46" Q6UWT4 5 147880726-147906538 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "salivary gland: 181.8;skin 1: 113.1" "Group enriched" "Detected in some" 12 "Early spermatids: 320.9;Late spermatids: 189.9" "Cancer enhanced" "Detected in many" "renal cancer: 8.3" "Region enriched" "Detected in single" 10 "cerebellum: 2.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 54.2;PC-3: 90.8;SiHa: 20.2;U-2 OS: 58.2;U-251 MG: 23.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA058999, HPA079692" Supported Approved "Nuclear speckles,Mitochondria" "Secreted in other tissues" NA NA 54000 "Cluster 31: Skin - Epidermis development" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" "Nuclear speckles" Mitochondria "HPA058999: , HPA079692: " "unprognostic (1.72e-1)" "prognostic unfavorable (3.98e-4)" "unprognostic (1.26e-4)" "unprognostic (9.75e-3)" "unprognostic (2.95e-3)" "unprognostic (1.69e-3)" "unprognostic (1.99e-2)" "unprognostic (3.08e-2)" "unprognostic (2.22e-1)" "unprognostic (4.96e-2)" "unprognostic (2.86e-3)" "unprognostic (1.10e-1)" "prognostic unfavorable (1.75e-9)" "unprognostic (6.48e-3)" "unprognostic (3.47e-2)" "unprognostic (6.01e-2)" "unprognostic (2.79e-2)" 0.4 0.0 0.0 0.0 0.0 0.0 13.5 2.3 0.1 1.6 0.7 0.4 0.0 0.1 0.4 0.4 0.0 0.2 9.0 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 2.2 0.2 0.9 0.0 0.6 181.8 0.1 0.8 113.1 0.0 3.2 0.0 0.0 0.0 19.2 0.0 0.3 0.2 0.1 0.3 0.0 3.6 0.0 0.7 0.0 0.0 0.0 0.4 0.0 0.0 2.4 1.4 0.0 0.0 0.4 0.0 0.0 0.1 0.0 1.0 0.3 0.0 0.6 0.0 0.2 0.2 0.0 4.6 0.2 0.0 0.0 0.0 0.0 1.1 0.0 8.9 54.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 90.8 0.0 0.5 0.0 0.0 0.1 0.0 0.0 20.2 0.3 0.3 11.1 0.0 0.0 0.0 10.0 58.2 0.8 23.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.8 0.0 0.0 9.2 3.7 11.0 15.7 0.2 1.8 0.0 0.5 0.2 0.0 0.0 15.9 320.9 0.7 0.4 0.3 0.0 0.0 0.0 3.3 0.6 0.2 0.0 3.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 189.9 1.8 0.2 3.6 0.0 0.6 7.7 0.0 0.0 0.0 4.2 0.0 0.4 0.0 1.3 0.0 0.0 0.0 0.3 0.0 0.0 2.1 1.1 0.8 0.0 20.6 1.4 0.1 0.0 0.0 0.2 C5orf52 ENSG00000187658 "Chromosome 5 open reading frame 52" A6NGY3 5 157671533-157680158 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "testis: 35.9" "Cell type enriched" "Detected in some" 4 "Late spermatids: 1980.5" "Cancer enriched" "Detected in single" 4 "colorectal cancer: 1.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected" "Not detected" NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (3.20e-2)" "unprognostic (1.01e-1)" "unprognostic (2.73e-2)" "unprognostic (3.50e-1)" "unprognostic (3.64e-1)" "unprognostic (1.32e-1)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.6 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 35.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.2 0.1 0.2 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 401.1 1.5 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 1980.5 7.8 0.6 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.1 5.8 6.4 0.1 0.0 0.1 0.0 0.0 0.0 6.6 0.0 0.0 26.4 4.6 0.0 0.0 0.0 0.0 0.0 1.2 0.0 C5orf58 ENSG00000234511 "Chromosome 5 open reading frame 58" C9J3I9 5 170232447-170252575 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in many" 35 "testis: 216.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "testis cancer: 1.3" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 12 "U-266/84: 85.6" "Not detected" "Not detected" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 16: U-266 - Nucleosome" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (9.24e-2)" "unprognostic (1.93e-2)" "unprognostic (1.61e-2)" "unprognostic (5.55e-2)" "unprognostic (2.92e-1)" "unprognostic (1.35e-1)" "unprognostic (5.33e-6)" "unprognostic (1.01e-1)" "unprognostic (5.61e-2)" "unprognostic (8.48e-2)" "unprognostic (1.85e-1)" "unprognostic (2.78e-1)" "unprognostic (3.29e-10)" "unprognostic (4.83e-3)" "unprognostic (5.45e-2)" "unprognostic (3.94e-2)" "unprognostic (8.27e-2)" 3.1 0.7 0.1 2.7 0.3 6.2 2.5 0.2 2.2 1.3 0.4 0.8 0.6 0.5 0.0 0.4 0.7 1.1 0.9 0.1 0.1 0.6 1.0 4.9 2.2 0.8 0.5 0.4 0.3 0.0 0.6 1.2 1.1 1.0 0.0 0.0 1.9 0.0 0.5 0.9 1.4 0.0 0.4 3.6 0.6 216.4 0.8 0.0 0.9 0.0 0.1 0.9 1.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 3.5 0.3 0.0 0.0 0.0 0.0 0.0 0.7 0.0 2.9 0.0 0.0 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 6.9 0.8 0.0 0.0 0.0 0.0 0.0 2.6 85.6 0.0 0.0 1.0 0.0 0.0 0.2 0.5 0.6 0.3 0.4 0.0 0.4 0.6 0.0 0.0 0.3 0.9 1.0 0.6 0.3 0.0 0.0 0.0 0.1 0.3 0.2 2.2 0.1 0.1 0.8 0.5 1.1 0.4 0.8 1.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 C7orf57 ENSG00000164746 "Chromosome 7 open reading frame 57" Q8NEG2 7 48035511-48061304 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.0;choroid plexus: 6.4;fallopian tube: 13.9" "Group enriched" "Detected in some" 5 "Endometrial ciliated cells: 52.7;Respiratory ciliated cells: 127.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 3.4;hTERT-HME1: 5.5;U-266/70: 3.2;U-698: 1.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA021286 Enhanced NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 30: Epithelial cell lines - Translation" "Cluster 49: Ciliated cells - Cilium organization" "HPA021286: AB_1845760" "unprognostic (1.74e-2)" "unprognostic (4.82e-2)" "unprognostic (3.13e-2)" "unprognostic (1.28e-2)" "unprognostic (2.77e-3)" "unprognostic (3.22e-2)" "unprognostic (1.21e-2)" "unprognostic (1.32e-1)" "unprognostic (3.29e-1)" "unprognostic (1.37e-1)" "unprognostic (4.98e-2)" "unprognostic (2.88e-1)" "unprognostic (3.93e-5)" "unprognostic (5.17e-3)" "unprognostic (6.18e-2)" "unprognostic (3.42e-3)" "unprognostic (1.20e-1)" 0.0 0.0 0.7 0.0 0.8 0.2 0.1 0.5 0.3 0.4 6.4 0.0 0.1 0.4 0.0 0.8 13.9 0.0 0.1 0.7 0.9 0.1 0.0 2.2 0.0 4.0 3.8 0.0 0.0 0.6 0.2 0.0 2.3 0.0 0.0 0.5 0.1 0.0 0.0 0.1 0.0 0.0 2.9 0.0 0.0 3.7 0.9 0.0 0.2 0.0 0.1 0.0 0.4 2.0 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.2 0.0 1.3 0.0 0.1 0.1 3.4 0.2 0.0 0.5 0.4 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.3 0.5 0.2 0.3 3.2 0.5 1.9 0.7 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.8 0.5 0.3 0.7 0.9 4.0 3.8 2.3 2.9 0.9 2.0 0.0 0.0 3.0 0.3 0.1 0.0 0.0 4.7 0.0 0.0 0.0 0.1 1.0 0.0 15.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 5.9 52.7 0.6 0.2 0.0 0.0 0.5 0.0 0.1 0.6 0.0 1.1 2.5 0.0 0.0 0.0 0.1 0.0 0.5 0.0 6.1 0.0 0.4 3.5 0.0 0.3 0.0 0.0 0.0 1.1 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 127.6 0.9 0.0 0.0 2.7 16.1 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.1 C8B ENSG00000021852 "Complement C8 beta chain" P07358 1 56929207-56966140 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement alternate pathway, Complement pathway, Cytolysis, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 156 "liver: 840.0" "Cell type enriched" "Detected in some" 18 "Hepatocytes: 295.1" "Cancer enriched" "Detected in some" 181 "liver cancer: 107.0" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 22 "basophil: 2.1" "Lineage enriched" "Detected in single" 22 "granulocytes: 2.1" "Cell line enriched" "Detected in single" 4 "Hep G2: 1.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA023694 Supported "Secreted to blood" NA NA 6700000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "HPA023694: AB_1847128" "unprognostic (6.65e-2)" "prognostic favorable (9.31e-5)" "unprognostic (2.37e-1)" "unprognostic (2.37e-1)" "unprognostic (1.29e-2)" "unprognostic (6.57e-2)" "unprognostic (5.12e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 840.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 15.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.2 1.0 0.0 0.1 0.0 5.3 0.0 0.7 0.0 0.0 0.0 0.3 0.0 0.0 7.1 295.1 0.1 0.0 0.1 0.0 0.0 7.6 0.0 11.6 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.0 C8orf74 ENSG00000171060 "Chromosome 8 open reading frame 74" Q6P047 8 10672628-10700590 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 171 "testis: 17.0" "Group enriched" "Detected in some" 90 "Early spermatids: 186.5;Late spermatids: 392.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA027986 Uncertain Uncertain Nucleoplasm NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 34: Spermatids - Unknown function" Nucleoplasm "HPA027986: AB_10600762" "unprognostic (4.24e-2)" "unprognostic (5.62e-2)" "unprognostic (4.68e-2)" "unprognostic (5.54e-2)" "unprognostic (2.37e-2)" "unprognostic (1.56e-4)" "unprognostic (6.82e-2)" "unprognostic (2.20e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 186.5 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 392.8 1.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 C8orf88 ENSG00000253250 "Chromosome 8 open reading frame 88" P0DMB2 8 90958471-90985238 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 91.6" "Cell type enhanced" "Detected in many" "Early spermatids: 612.7;Late spermatids: 138.4;Spermatocytes: 329.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 3.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HHSteC: 63.4" "Low region specificity" "Detected in all" HPA078486 Enhanced NA NA "Cluster 15: NK-cells - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 30: Epithelial cell lines - Translation" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA078486: " "unprognostic (2.17e-1)" "unprognostic (7.00e-2)" "unprognostic (2.51e-2)" "unprognostic (2.95e-4)" "unprognostic (4.07e-2)" "unprognostic (1.19e-1)" "unprognostic (8.44e-3)" "unprognostic (1.12e-2)" "prognostic unfavorable (4.90e-4)" "unprognostic (1.71e-2)" "unprognostic (9.89e-2)" "unprognostic (7.18e-2)" "unprognostic (6.04e-2)" "unprognostic (2.59e-3)" "unprognostic (1.17e-2)" "unprognostic (3.57e-2)" "prognostic unfavorable (6.23e-6)" 8.0 3.8 2.2 4.2 2.9 11.0 6.7 2.4 2.7 10.6 4.9 32.9 2.1 21.4 13.1 8.7 11.9 7.1 38.2 2.2 3.2 4.9 1.0 4.7 1.7 3.0 2.6 13.3 1.3 0.4 4.1 3.5 3.0 13.9 5.7 1.6 2.4 23.5 1.4 7.1 6.5 30.8 3.2 3.0 13.3 91.6 2.7 13.0 10.9 1.8 1.4 19.0 7.8 4.3 0.1 2.4 13.4 1.2 15.4 13.4 0.2 14.6 22.8 19.8 29.7 0.1 3.8 0.3 1.3 14.9 20.6 0.1 0.2 1.1 36.7 0.0 38.6 41.7 11.5 0.0 63.4 0.0 1.3 14.1 0.3 22.3 37.0 28.9 2.1 13.6 25.0 23.9 30.3 0.0 39.7 14.9 3.3 0.0 0.7 0.0 26.1 0.1 16.3 0.1 11.4 19.8 0.6 0.0 19.6 15.1 0.0 1.9 8.5 22.8 38.0 0.3 15.5 33.3 33.4 21.2 22.6 0.0 10.5 0.0 0.0 0.0 0.9 0.0 1.2 1.1 0.8 1.0 0.2 0.9 0.7 1.4 0.0 3.8 0.0 3.2 0.6 0.4 2.2 2.9 2.4 2.7 2.2 3.2 3.0 2.6 3.0 3.2 2.7 4.3 6.4 0.0 1.1 1.3 2.9 18.9 9.3 1.0 19.4 0.0 0.5 8.6 12.4 2.8 0.1 3.7 0.0 0.2 0.8 0.0 5.9 1.1 612.7 0.3 9.0 4.7 0.0 55.6 3.1 0.0 0.9 13.7 0.0 0.2 2.5 4.9 5.0 0.0 0.6 0.0 6.4 0.0 0.0 0.8 3.8 138.4 19.0 1.7 10.6 1.9 0.6 0.9 0.0 2.0 4.0 3.6 0.0 21.8 3.0 6.6 0.0 1.4 0.1 0.2 19.7 8.2 21.1 329.5 30.7 6.9 26.6 0.0 2.8 2.0 0.0 1.2 C9orf57 ENSG00000204669 "Chromosome 9 open reading frame 57" Q5W0N0 9 72051376-72072721 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 37 "testis: 13.0" "Cell type enriched" "Detected in some" 6 "Spermatocytes: 13.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (3.26e-2)" "unprognostic (1.15e-1)" "unprognostic (5.05e-2)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 13.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CA12 HsT18816 ENSG00000074410 "Carbonic anhydrase 12" O43570 15 63321378-63381846 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins" Lyase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 290.2;skin 1: 142.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 174.6;Distal enterocytes: 422.6;Paneth cells: 160.8;Squamous epithelial cells: 185.3;Suprabasal keratinocytes: 252.2;Undifferentiated cells: 138.8" "Cancer enhanced" "Detected in all" "renal cancer: 109.3" "Region enhanced" "Detected in many" "basal ganglia: 42.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 213.0;ASC TERT1: 213.0;RT4: 226.2;SK-BR-3: 177.9;T-47d: 286.8;U-138 MG: 300.5;U-87 MG: 361.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008773, CAB025181, CAB062549, CAB068179, HPA073203" Enhanced NA NA 52000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB025181: , CAB062549: AB_2665617, CAB068179: AB_2665616, HPA008773: AB_1078394, HPA073203: AB_2686580" "unprognostic (2.01e-1)" "unprognostic (8.38e-3)" "unprognostic (3.47e-1)" "unprognostic (3.25e-3)" "unprognostic (2.73e-2)" "unprognostic (2.47e-2)" "unprognostic (7.48e-2)" "unprognostic (3.43e-3)" "unprognostic (2.29e-1)" "unprognostic (4.67e-2)" "prognostic unfavorable (3.80e-6)" "unprognostic (2.59e-1)" "unprognostic (1.51e-1)" "unprognostic (2.38e-1)" "unprognostic (6.56e-2)" "unprognostic (7.26e-2)" "unprognostic (1.21e-1)" 8.3 0.2 6.1 18.7 42.9 0.1 42.8 5.2 7.2 50.7 129.0 104.1 0.4 28.4 4.1 75.4 25.0 7.7 3.2 6.8 6.6 290.2 0.7 3.0 0.3 0.9 9.6 0.6 70.2 0.3 10.7 2.3 3.2 5.5 94.2 1.9 26.3 8.7 0.6 142.1 8.2 56.2 0.9 0.8 7.9 0.6 16.1 0.1 4.6 0.1 8.7 27.4 49.0 1.5 0.0 213.0 3.5 0.5 27.3 213.0 11.2 15.7 13.7 2.5 4.1 1.6 0.5 0.0 51.4 12.6 81.7 1.1 0.0 10.4 6.2 0.3 7.7 0.0 13.9 0.4 0.6 0.0 0.3 81.3 11.4 63.6 20.4 0.1 2.7 0.1 0.0 0.3 2.8 125.2 0.3 0.2 3.4 0.0 33.4 0.1 0.0 0.1 0.2 226.2 1.8 0.2 0.9 177.9 0.0 2.1 286.8 0.1 0.4 300.5 16.0 10.1 0.2 0.0 0.0 0.1 361.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 42.9 5.2 7.2 6.8 6.6 0.9 9.6 3.2 0.9 16.1 1.5 0.7 0.0 6.9 11.4 1.1 174.6 20.0 87.7 93.4 0.1 93.5 50.4 1.3 1.5 30.3 40.5 0.0 0.4 1.6 422.6 54.8 17.2 12.1 28.4 6.2 2.1 8.4 0.0 1.3 58.4 2.0 14.6 8.2 75.0 1.3 0.3 0.0 0.2 0.6 0.0 0.8 111.4 20.3 0.3 11.9 3.9 0.0 4.0 23.2 0.0 0.0 2.7 0.0 1.0 0.1 10.2 160.8 0.0 0.0 19.8 15.6 73.9 6.9 0.2 0.0 0.2 4.1 0.0 0.0 185.3 252.2 1.8 2.8 0.1 138.8 17.4 CA14 ENSG00000118298 "Carbonic anhydrase 14" Q9ULX7 1 150257251-150265078 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 33.3;retina: 39.4;skeletal muscle: 33.7;tongue: 47.4" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 69.5;Melanocytes: 53.4;Muller glia cells: 164.5;Oligodendrocytes: 25.7" "Cancer enriched" "Detected in many" 5 "melanoma: 23.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "AF22: 102.2;AN3-CA: 65.9;NTERA-2: 83.9;SK-MEL-30: 217.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008482 Approved Approved "Plasma membrane" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 5: Muller glia cells - Visual perception" "Plasma membrane" "HPA008482: AB_1078395" "unprognostic (3.06e-2)" "unprognostic (1.67e-1)" "unprognostic (2.10e-2)" "unprognostic (3.25e-2)" "prognostic favorable (8.47e-4)" "unprognostic (7.28e-2)" "unprognostic (4.48e-2)" "unprognostic (1.49e-1)" "unprognostic (2.10e-1)" "unprognostic (2.47e-1)" "unprognostic (5.46e-2)" "unprognostic (1.73e-1)" "unprognostic (5.89e-3)" "unprognostic (1.91e-1)" "unprognostic (1.49e-1)" "unprognostic (1.22e-1)" "unprognostic (5.80e-2)" 0.0 0.2 8.6 0.2 14.4 1.2 0.3 15.9 27.6 0.1 33.3 3.8 0.4 0.1 0.4 1.9 1.7 0.6 7.6 8.7 11.3 0.3 8.7 0.2 0.1 14.3 14.0 1.4 0.2 3.4 0.5 0.3 14.6 4.0 0.7 39.4 0.4 20.3 33.7 5.4 1.3 0.5 12.5 0.2 1.2 0.5 13.3 0.0 1.0 47.4 0.0 0.6 0.1 20.6 0.9 0.2 102.2 65.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.7 0.1 0.5 0.0 0.1 0.3 0.2 0.1 0.0 0.2 1.1 0.3 0.3 6.9 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.8 0.1 0.6 0.0 0.9 0.3 0.3 83.9 0.4 1.1 0.1 0.3 0.3 0.0 0.2 3.2 1.8 0.0 0.3 217.9 14.6 0.8 0.4 0.1 0.1 0.2 0.2 0.4 0.9 4.9 0.4 0.7 0.5 0.2 0.0 0.2 0.4 0.4 0.5 0.1 0.5 0.2 0.3 0.0 0.6 0.3 0.3 0.5 0.0 0.1 0.6 0.0 0.0 8.6 14.4 15.9 27.6 8.7 11.3 14.3 14.0 14.6 12.5 13.3 20.6 0.1 3.2 0.5 0.3 0.2 2.2 0.3 0.3 0.0 1.3 0.1 0.0 69.5 0.0 0.7 0.0 0.0 0.4 0.0 0.3 0.0 0.8 0.0 0.3 0.1 0.6 0.0 0.0 0.1 0.7 0.1 3.4 0.0 0.2 0.0 0.0 0.0 6.1 0.1 0.0 0.1 0.3 0.0 0.3 0.9 0.2 0.9 0.1 53.4 0.0 0.0 164.5 0.0 0.0 25.7 1.9 0.3 3.4 0.0 0.3 0.0 0.1 0.1 4.9 0.0 0.6 0.5 0.0 0.2 0.0 0.4 0.3 0.1 0.0 0.2 0.5 CA2 "CA-II, CAII, Car2" ENSG00000104267 "Carbonic anhydrase 2" P00918 8 85463968-85481493 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Lyase "Disease variant, FDA approved drug targets, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 687.4;stomach 1: 1108.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 1773.2;Erythroid cells: 2448.1;Gastric mucus-secreting cells: 1380.7;Muller glia cells: 1536.4;Paneth cells: 781.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 51.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HaCaT: 263.8;HEK 293: 1097.8;THP-1: 461.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001550, CAB010102" Enhanced NA Yes 570000000 "Cluster 38: Basophils - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 6: Erythroid cells - Oxygen transport" "CAB010102: AB_626796, HPA001550: AB_1078393" "unprognostic (6.78e-2)" "unprognostic (3.06e-2)" "unprognostic (1.05e-2)" "unprognostic (1.63e-1)" "unprognostic (2.59e-1)" "unprognostic (9.24e-2)" "unprognostic (1.74e-1)" "unprognostic (1.72e-2)" "unprognostic (1.07e-1)" "unprognostic (5.23e-2)" "unprognostic (1.57e-1)" "unprognostic (9.89e-2)" "prognostic favorable (5.57e-6)" "unprognostic (2.45e-1)" "unprognostic (2.03e-1)" "unprognostic (1.32e-1)" "unprognostic (6.49e-3)" 7.4 10.1 95.9 36.8 127.5 246.8 37.9 122.1 143.8 5.0 444.0 687.4 285.2 2.9 10.6 19.8 2.7 112.7 15.9 105.2 107.8 331.2 273.5 43.1 6.6 115.5 112.0 0.4 55.1 10.1 6.1 19.6 114.2 1.9 643.6 390.4 74.7 68.4 42.7 81.0 31.3 32.3 98.2 8.4 1108.7 21.2 115.6 5.1 15.9 62.8 4.3 2.9 5.2 145.5 3.7 2.8 12.2 0.0 0.1 0.0 31.2 0.0 0.0 0.0 0.0 15.1 0.9 0.0 9.5 0.0 0.1 263.8 37.4 13.2 0.0 0.0 1097.8 35.8 17.0 0.5 0.0 23.7 5.1 0.0 63.9 0.0 3.7 0.0 0.0 0.0 0.3 0.2 0.0 0.4 0.4 41.4 3.7 86.5 0.0 21.2 1.3 0.5 3.7 8.8 0.2 0.3 5.0 0.0 0.1 9.6 0.0 461.5 0.0 0.0 6.6 0.0 0.4 0.4 1.0 0.1 1.8 0.1 0.0 51.2 5.3 8.6 0.2 15.0 7.4 1.3 0.1 0.8 15.4 3.0 0.0 0.0 12.6 0.1 13.4 1.4 0.0 33.3 95.9 127.5 122.1 143.8 105.2 107.8 115.5 112.0 114.2 98.2 115.6 145.5 19.4 16.0 79.9 34.0 19.6 90.6 1.3 152.5 17.6 23.1 56.9 18.4 19.8 430.4 22.4 161.8 64.6 15.2 2.4 1773.2 348.3 60.1 65.9 3.3 1.3 26.7 30.5 2448.1 1.4 11.3 403.1 6.4 1380.7 8.3 15.9 0.4 4.2 135.6 35.4 13.5 22.3 116.0 10.2 11.0 216.5 232.1 3.4 51.8 74.7 6.5 6.6 1536.4 1.0 3.0 226.4 16.1 781.9 2.2 10.3 3.5 0.3 468.2 3.9 66.1 0.0 12.1 8.2 3.1 2.8 31.2 111.7 17.1 11.7 0.7 390.8 0.5 CA5B ENSG00000169239 "Carbonic anhydrase 5B" Q9Y2D0 X 15688830-15788411 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 37.9;Muller glia cells: 35.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 22.3;fHDF/TERT166: 27.0;hTERT-HME1: 34.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA012618 Uncertain Supported Mitochondria NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 30: Epithelial cell lines - Translation" "Cluster 24: Non-specific - Transcription regulation" Mitochondria "HPA012618: AB_1846000" "unprognostic (1.62e-2)" "unprognostic (2.10e-3)" "unprognostic (2.86e-1)" "unprognostic (1.55e-3)" "unprognostic (1.16e-2)" "unprognostic (4.59e-5)" "unprognostic (2.50e-1)" "unprognostic (6.89e-4)" "unprognostic (4.11e-1)" "unprognostic (3.89e-3)" "unprognostic (1.54e-1)" "unprognostic (1.17e-1)" "prognostic favorable (6.66e-6)" "unprognostic (2.43e-1)" "unprognostic (1.38e-1)" "unprognostic (8.94e-2)" "unprognostic (3.08e-1)" 5.9 3.1 5.3 4.2 5.8 3.5 8.3 3.9 5.4 21.5 5.8 2.8 1.6 7.3 2.6 6.5 7.5 7.3 4.0 3.9 7.3 4.8 2.1 6.0 5.6 8.4 6.5 11.9 3.4 9.1 2.4 3.1 6.9 4.8 3.6 10.5 4.5 4.6 1.6 5.7 2.6 7.6 6.3 4.3 4.4 10.3 6.1 4.3 7.2 5.4 6.8 5.2 5.5 4.6 4.3 2.6 2.9 4.8 8.5 22.3 1.7 4.4 5.6 3.2 4.6 1.3 2.8 1.2 4.5 27.0 6.1 4.6 10.3 5.0 5.7 1.2 4.8 2.3 3.3 1.1 8.3 3.0 5.0 5.3 5.3 4.3 34.2 5.7 4.8 3.5 1.2 3.0 15.4 2.3 2.5 2.3 1.2 0.8 18.6 1.4 2.1 2.2 4.9 3.1 2.6 5.3 6.1 2.2 3.8 3.4 3.1 3.0 6.5 3.8 2.5 20.4 2.5 2.2 2.4 1.4 4.2 6.0 7.2 4.4 3.9 0.4 16.7 4.8 14.5 4.6 16.6 15.5 4.7 5.0 12.1 10.4 2.2 11.0 3.1 0.7 14.3 10.0 5.3 5.8 3.9 5.4 3.9 7.3 8.4 6.5 6.9 6.3 6.1 4.6 9.6 0.0 7.9 14.0 19.1 4.2 6.3 3.4 6.2 9.5 7.3 5.2 2.4 0.0 7.1 1.8 16.7 1.8 37.9 1.6 1.9 4.4 1.1 9.6 7.1 13.9 3.0 11.2 11.5 4.0 1.8 10.5 11.7 6.2 2.5 6.7 6.1 2.7 1.9 1.7 11.8 2.2 8.2 9.3 11.1 1.8 7.8 10.8 3.6 19.7 9.1 35.9 32.0 8.5 10.6 4.1 1.6 5.3 18.7 11.5 1.2 2.9 12.2 7.8 6.6 8.1 8.3 4.2 5.6 5.5 4.5 1.9 30.0 12.1 1.5 7.9 CA8 "CALS, CARP" ENSG00000178538 "Carbonic anhydrase 8" P35219 8 60185412-60281400 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 18.3;parathyroid gland: 40.1" "Cell type enhanced" "Detected in many" "Astrocytes: 92.7;Enteroendocrine cells: 35.2;Gastric mucus-secreting cells: 40.2;Oligodendrocyte precursor cells: 129.7" "Cancer enhanced" "Detected in many" "endometrial cancer: 7.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 24 "basophil: 76.2" "Lineage enriched" "Detected in many" 24 "granulocytes: 76.2" "Cell line enhanced" "Detected in some" "HEK 293: 10.1;JURKAT: 11.0;K-562: 20.3;NB-4: 12.3;OE19: 17.4" "Region enriched" "Detected in all" 38 "cerebellum: 1260.5" "Region enriched" "Detected in all" 9 "cerebellum: 86.3" "HPA024748, CAB025545, CAB047309" Enhanced NA NA "Cluster 38: Basophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 1: K-562 - Erythropoiesis" "Cluster 68: Oligodendrocytes - Mixed function" "CAB025545: , CAB047309: , HPA024748: AB_1846003" "unprognostic (1.55e-1)" "unprognostic (2.89e-2)" "unprognostic (4.43e-2)" "unprognostic (3.46e-3)" "unprognostic (6.67e-2)" "unprognostic (3.19e-1)" "unprognostic (3.85e-2)" "unprognostic (3.54e-2)" "unprognostic (1.28e-1)" "unprognostic (1.19e-1)" "prognostic favorable (5.79e-5)" "unprognostic (3.23e-2)" "unprognostic (1.68e-2)" "unprognostic (2.12e-1)" "unprognostic (1.71e-2)" "unprognostic (1.95e-1)" "unprognostic (1.41e-1)" 1.6 0.9 5.2 0.3 5.8 0.5 4.6 18.3 5.6 4.3 2.0 1.3 1.0 1.9 10.2 0.2 1.5 0.3 4.3 4.4 5.3 5.3 0.0 0.9 0.4 4.7 4.9 0.2 1.9 40.1 8.5 6.2 5.0 1.5 2.0 2.3 3.7 0.2 1.2 0.3 1.0 0.5 3.1 0.8 4.4 4.1 5.1 1.3 0.3 2.3 0.3 0.6 0.3 4.0 0.0 2.4 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 1.1 0.0 0.1 0.0 10.1 4.5 0.0 0.0 3.6 1.8 1.2 0.0 0.0 0.0 0.0 0.0 0.0 11.0 20.3 0.2 0.0 0.0 3.3 12.3 0.2 17.4 0.0 0.0 0.0 0.2 0.4 0.8 5.1 0.0 0.0 1.1 0.0 2.0 4.5 0.7 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.5 76.2 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.1 0.0 0.1 5.2 5.8 18.3 5.6 4.4 5.3 4.7 4.9 5.0 3.1 5.1 4.0 22.0 0.0 4.8 92.7 1.6 1.0 0.4 4.1 0.0 8.2 15.6 10.3 4.7 0.0 5.7 3.7 0.0 8.3 10.9 2.0 3.9 8.1 9.9 9.8 2.4 16.7 35.2 13.5 4.7 6.0 0.3 4.0 40.2 26.2 0.0 1.1 0.0 0.0 9.9 0.0 25.6 25.0 6.1 1.9 1.1 4.9 1.5 1.1 7.2 18.7 0.0 2.6 1.0 129.7 0.4 1.6 3.5 1.5 14.0 2.1 0.3 0.0 1.2 1.0 0.0 0.8 2.3 3.8 5.5 0.2 0.4 1.4 0.7 3.1 3.3 1.5 CA9 "CAIX, MN" ENSG00000107159 "Carbonic anhydrase 9" Q16790 9 35673918-35681159 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "stomach 1: 289.3" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 275.3;Cholangiocytes: 62.9;Early spermatids: 205.8;Gastric mucus-secreting cells: 259.5" "Cancer enhanced" "Detected in many" "renal cancer: 85.9" "Region enriched" "Detected in single" 9 "cerebellum: 5.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "A-431: 189.3;HDLM-2: 98.1;hTERT-RPE1: 113.1;U-87 MG: 374.4" "Region enhanced" "Detected in many" "cerebellum: 12.3" "Low region specificity" "Detected in all" "CAB005100, CAB017107, HPA055207" Enhanced Supported "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 4: Stomach - Digestion" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" "CAB005100: AB_2066539, CAB017107: , HPA055207: AB_2682738" "unprognostic (8.01e-3)" "unprognostic (1.34e-2)" "unprognostic (2.28e-1)" "unprognostic (2.00e-2)" "unprognostic (1.59e-2)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.71e-5)" "unprognostic (1.47e-2)" "unprognostic (3.90e-2)" "unprognostic (1.29e-1)" "unprognostic (6.24e-3)" "unprognostic (1.13e-1)" "prognostic unfavorable (2.22e-7)" "unprognostic (7.29e-2)" "prognostic favorable (9.50e-4)" "unprognostic (2.97e-3)" "unprognostic (8.67e-2)" 3.8 0.4 0.0 0.2 0.0 0.0 0.1 5.6 0.6 0.5 0.0 0.6 14.5 0.2 0.1 0.8 0.4 24.4 2.0 0.2 0.1 0.2 1.3 0.2 0.0 0.0 0.1 0.7 6.6 0.0 0.5 0.0 0.2 0.5 0.0 1.0 0.1 0.1 0.1 8.2 13.6 0.1 0.0 0.0 289.3 5.5 0.5 0.0 0.0 0.0 0.0 0.7 0.7 0.0 189.3 0.3 0.0 0.0 0.0 0.0 0.0 0.2 3.6 0.3 2.5 0.0 0.1 0.0 0.1 0.0 0.5 5.7 0.0 0.9 1.5 98.1 0.0 0.0 0.7 0.4 0.0 0.0 0.2 0.4 0.0 0.0 0.3 113.1 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.3 0.2 0.5 0.0 0.0 10.6 0.0 0.6 1.6 0.0 0.0 0.1 0.7 0.0 0.0 0.2 0.0 18.9 0.4 0.0 4.7 0.0 0.4 0.1 374.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.6 0.6 0.2 0.1 0.0 0.1 0.2 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.2 4.5 0.7 275.3 0.0 0.4 0.1 0.0 0.4 62.9 28.1 0.0 0.0 0.0 0.0 0.1 0.0 49.1 205.8 0.0 0.1 0.2 0.0 0.0 0.1 50.9 0.6 1.2 259.5 0.2 0.0 0.4 0.7 0.0 0.1 0.0 0.6 4.0 18.3 0.0 0.0 19.6 1.5 0.1 0.0 0.0 0.6 1.3 0.0 0.0 0.0 26.6 0.0 0.7 0.3 0.8 0.7 0.1 5.5 0.0 0.0 0.0 1.5 0.9 4.0 0.0 3.1 0.3 0.1 0.7 5.3 0.4 CAB39L "bA103J18.3, FLJ12577, MO2L" ENSG00000102547 "Calcium binding protein 39 like" Q9H9S4 13 49308650-49444064 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 200.0" "Cancer enhanced" "Detected in all" "prostate cancer: 28.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CACO-2: 41.8;RT4: 43.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003686, HPA045954, HPA076632" Approved Approved Vesicles NA NA "Cluster 10: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 15: RT4 - Unknown function" "Cluster 50: Fibroblasts - ECM organization" Vesicles "CAB003686: AB_426084, HPA045954: AB_2679512, HPA076632: " "unprognostic (3.90e-2)" "unprognostic (1.09e-1)" "unprognostic (4.13e-1)" "unprognostic (5.01e-1)" "unprognostic (3.29e-1)" "unprognostic (1.94e-1)" "unprognostic (2.82e-1)" "unprognostic (2.94e-2)" "unprognostic (2.78e-2)" "prognostic unfavorable (2.28e-4)" "unprognostic (3.08e-2)" "prognostic favorable (7.91e-4)" "prognostic favorable (1.94e-13)" "unprognostic (6.59e-2)" "unprognostic (8.31e-2)" "unprognostic (4.96e-2)" "unprognostic (8.05e-3)" 23.7 37.4 25.0 4.4 26.4 2.2 37.3 21.0 20.7 14.5 68.2 57.7 6.0 15.3 16.3 31.2 18.3 16.5 22.0 24.6 38.7 14.0 5.3 19.5 4.2 24.6 35.0 21.5 12.0 29.2 8.4 12.4 25.1 41.4 11.6 14.8 16.9 22.5 7.5 16.1 12.5 11.5 27.4 4.0 27.1 33.4 31.4 9.4 9.7 13.0 5.2 26.5 17.3 28.4 1.6 1.7 9.8 2.8 9.3 8.7 14.8 9.3 17.9 5.9 4.1 41.8 6.0 14.2 1.2 6.5 6.5 3.4 5.4 6.2 10.2 4.7 4.5 3.7 2.0 2.6 5.2 3.3 1.6 6.4 4.8 4.4 6.8 7.3 8.0 2.2 0.7 3.2 8.1 2.8 3.2 2.4 7.6 5.4 2.7 2.8 1.3 2.3 8.3 43.4 1.2 3.7 5.1 11.8 12.1 11.8 18.4 4.9 7.6 2.5 2.7 5.3 7.6 2.5 2.3 16.3 2.8 2.5 5.7 6.7 2.6 5.4 2.6 2.4 2.0 2.7 3.2 3.4 2.6 1.6 2.3 2.3 5.6 1.9 2.1 0.4 3.6 2.3 25.0 26.4 21.0 20.7 24.6 38.7 24.6 35.0 25.1 27.4 31.4 28.4 6.9 16.0 11.9 52.2 2.4 3.1 12.6 6.6 7.4 6.4 27.1 14.4 14.5 4.3 13.4 11.0 6.2 26.4 3.1 3.9 11.7 10.1 200.0 8.3 9.2 5.4 2.4 1.7 45.0 10.6 14.0 42.5 5.6 3.7 4.5 4.2 3.9 1.9 6.4 1.7 32.4 2.4 16.2 3.5 4.7 32.1 15.5 5.0 12.4 24.4 5.6 14.9 7.2 50.3 43.3 10.3 2.0 11.7 4.6 16.7 0.8 5.0 17.7 5.2 6.6 9.4 16.8 46.0 5.0 16.0 4.4 29.0 3.6 3.9 2.3 21.7 CABCOCO1 "bA63A2.1, C10orf107, Em:AC022398.2, MGC44593" ENSG00000183346 "Ciliary associated calcium binding coiled-coil 1" Q8IVU9 10 61662929-61766766 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 26.6;testis: 15.5" "Group enriched" "Detected in some" 10 "Endometrial ciliated cells: 60.4;Respiratory ciliated cells: 88.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "MOLT-4: 26.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA041398 Enhanced Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 49: Ciliated cells - Cilium organization" Centrosome "Nucleoplasm, Cytosol" "HPA041398: AB_10794374" "unprognostic (1.89e-3)" "unprognostic (7.37e-2)" "unprognostic (2.23e-1)" "prognostic favorable (1.79e-4)" "prognostic unfavorable (4.88e-4)" "unprognostic (1.02e-1)" "unprognostic (2.55e-1)" "unprognostic (5.52e-2)" "unprognostic (4.43e-2)" "unprognostic (3.31e-1)" "unprognostic (1.16e-1)" "unprognostic (1.26e-2)" "unprognostic (3.46e-1)" "unprognostic (1.52e-3)" "unprognostic (2.48e-1)" "unprognostic (2.90e-2)" "unprognostic (1.33e-2)" 1.0 0.5 4.2 0.2 4.2 0.0 1.2 3.5 3.9 4.2 5.9 1.2 0.3 3.5 0.5 0.3 26.6 0.8 0.2 4.4 4.6 1.8 0.3 4.1 0.0 6.8 8.9 0.2 0.5 2.9 4.2 0.8 7.2 4.1 0.6 0.9 1.0 2.5 0.1 0.3 0.5 0.7 8.3 1.0 0.5 15.5 4.0 0.1 0.7 0.0 0.1 0.4 0.6 7.8 0.0 0.2 0.1 0.0 0.0 2.5 0.0 0.4 1.7 0.3 0.6 0.0 0.0 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.2 2.6 0.0 0.0 1.2 0.0 0.0 0.2 0.0 0.1 0.1 1.0 0.9 0.5 0.1 0.0 0.1 0.0 26.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.5 0.0 0.0 5.2 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 4.2 3.5 3.9 4.4 4.6 6.8 8.9 7.2 8.3 4.0 7.8 1.9 3.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.5 0.0 0.0 7.4 3.7 0.0 0.3 0.0 0.0 0.0 0.8 0.0 60.4 4.1 0.4 0.0 0.0 0.0 0.2 0.2 0.5 0.0 1.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.2 88.9 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.4 0.2 1.2 0.0 0.0 CACNA1E "BII, CACH6, CACNL1A6, Cav2.3" ENSG00000198216 "Calcium voltage-gated channel subunit alpha1 E" Q15878 1 181317690-181808084 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 28 "brain: 42.8" "Cell type enhanced" "Detected in some" "Excitatory neurons: 188.7;Inhibitory neurons: 116.0;Oligodendrocyte precursor cells: 73.9;Oligodendrocytes: 34.2" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 1.6;NB-4: 1.0;NTERA-2: 1.1;U-266/70: 2.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042515, CAB079032" Approved Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 29: U-266 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "Actin filaments, Cytosol" "CAB079032: , HPA042515: " "unprognostic (3.96e-3)" "unprognostic (1.89e-1)" "unprognostic (1.05e-2)" "unprognostic (1.54e-5)" "unprognostic (6.56e-2)" "unprognostic (3.16e-2)" "unprognostic (4.30e-3)" "unprognostic (1.18e-1)" "unprognostic (2.40e-1)" "unprognostic (9.48e-3)" "unprognostic (1.04e-1)" "unprognostic (2.06e-1)" "unprognostic (9.85e-7)" "unprognostic (1.74e-2)" "unprognostic (2.07e-2)" "unprognostic (1.16e-1)" "unprognostic (3.75e-2)" 0.0 1.0 33.5 0.6 30.5 1.2 0.0 0.0 34.6 0.0 0.0 0.1 0.0 0.0 1.5 0.2 0.7 0.0 0.3 42.8 3.4 1.3 0.0 0.1 0.4 4.6 6.2 0.0 0.0 0.0 0.1 0.1 0.9 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.2 0.2 9.7 0.4 0.1 1.0 3.8 0.0 0.0 0.0 0.2 0.0 0.0 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.1 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 33.5 30.5 0.0 34.6 42.8 3.4 4.6 6.2 0.9 9.7 3.8 1.1 0.0 0.0 0.0 3.6 0.0 0.1 0.0 0.0 0.0 4.6 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.1 0.0 0.4 0.0 0.0 188.7 0.0 0.0 0.1 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 116.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 6.5 0.0 0.2 0.0 73.9 34.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.3 0.0 0.0 0.1 0.2 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 CACNB4 EJM4 ENSG00000182389 "Calcium voltage-gated channel auxiliary subunit beta 4" O00305 2 151832771-152099167 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 16.4;skin 1: 7.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 495.6;Inhibitory neurons: 470.7;Microglial cells: 136.8;Oligodendrocyte precursor cells: 155.3" "Cancer enhanced" "Detected in single" "glioma: 0.9" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 5 "neutrophil: 3.4" "Lineage enriched" "Detected in single" 5 "granulocytes: 3.4" "Cell line enhanced" "Detected in some" "Hep G2: 4.1;HMC-1: 20.2;U-937: 5.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015601 Approved NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 6: Brain - Smell perception" "Cluster 3: HMC-1 - Innate immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA015601: AB_1845873" "unprognostic (2.92e-1)" "unprognostic (1.98e-1)" "unprognostic (1.80e-1)" "unprognostic (1.29e-1)" "unprognostic (1.14e-1)" "unprognostic (1.49e-2)" "unprognostic (3.70e-1)" "unprognostic (9.42e-4)" "unprognostic (1.23e-1)" "unprognostic (1.98e-1)" "unprognostic (1.05e-3)" "unprognostic (2.02e-1)" "unprognostic (1.55e-2)" "unprognostic (7.26e-3)" "unprognostic (3.93e-2)" "unprognostic (9.55e-3)" "unprognostic (2.45e-1)" 0.7 0.7 4.6 0.4 12.0 0.7 1.5 15.2 16.4 0.4 1.3 0.3 0.4 0.4 0.6 1.4 0.3 0.9 0.3 6.2 2.3 1.4 0.1 2.0 0.3 0.2 5.6 0.3 0.4 0.4 1.8 0.9 0.3 2.0 0.5 1.8 1.7 1.9 0.1 7.3 0.3 0.5 0.3 0.4 0.6 2.3 6.8 1.1 1.4 0.2 1.0 2.0 0.5 6.8 0.0 0.0 0.7 0.6 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.9 0.0 1.9 0.0 0.1 0.3 3.2 0.0 0.2 4.1 0.0 0.2 20.2 0.2 0.1 0.4 0.0 1.7 0.0 0.8 0.0 0.5 0.1 0.0 0.2 0.3 0.5 0.1 0.6 2.0 0.2 0.6 1.1 0.5 1.3 0.7 0.0 0.0 0.0 0.1 3.3 0.8 0.0 1.8 2.0 0.6 0.4 0.3 0.0 0.0 0.4 5.9 0.1 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 3.4 0.0 0.0 0.6 0.0 0.1 4.6 12.0 15.2 16.4 6.2 2.3 0.2 5.6 0.3 0.3 6.8 6.8 1.1 12.8 53.3 80.6 0.8 12.4 16.3 3.5 30.7 9.9 6.8 7.2 1.3 0.0 3.8 3.7 4.2 0.1 0.3 0.3 3.9 0.5 0.9 3.0 3.0 1.3 0.0 0.0 495.6 1.5 0.0 7.9 1.1 5.4 0.0 84.1 0.7 0.0 3.4 20.2 470.7 0.0 0.0 1.2 7.5 2.1 3.4 2.4 1.8 136.8 1.2 2.3 1.0 155.3 31.2 1.0 0.1 4.5 2.0 29.0 0.1 0.9 1.2 3.4 0.0 0.6 1.2 0.7 4.1 3.2 8.2 0.0 1.1 6.6 0.1 16.3 CALB2 CAL2 ENSG00000172137 "Calbindin 2" P22676 16 71358713-71390436 "Plasma proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 100.5;brain: 131.9;breast: 53.5" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 97.8;granulocytes: 251.5;Granulosa cells: 44.1;Theca cells: 70.2" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in all" 4 "hypothalamus: 76.3;medulla oblongata: 89.5;midbrain: 42.2;pons: 86.7;thalamus: 131.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 21.5;HEL: 63.9;HMC-1: 133.0;U-2 OS: 38.0" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "thalamus: 449.0" "CAB000106, HPA007305, HPA007306" Enhanced Supported Enhanced Cytosol NA NA 9600 "Cluster 73: Brain - Neuropeptide signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" Cytosol "CAB000106: AB_2068519, HPA007305: AB_1078386, HPA007306: AB_1078385" "unprognostic (1.10e-1)" "unprognostic (1.90e-2)" "prognostic unfavorable (5.78e-5)" "unprognostic (1.75e-3)" "unprognostic (5.80e-2)" "unprognostic (1.43e-1)" "unprognostic (1.59e-1)" "unprognostic (4.55e-3)" "unprognostic (4.28e-1)" "unprognostic (1.32e-1)" "unprognostic (3.06e-3)" "unprognostic (1.35e-2)" "unprognostic (5.54e-4)" "unprognostic (1.97e-3)" "unprognostic (6.30e-2)" "unprognostic (4.72e-2)" "unprognostic (1.04e-2)" 100.5 36.6 19.9 4.1 15.4 0.0 53.5 16.5 20.0 3.5 4.1 13.8 0.7 0.7 0.5 7.7 7.7 1.1 7.7 12.8 76.3 0.3 0.2 3.6 0.1 89.5 42.2 11.4 0.7 0.0 14.3 0.0 86.7 0.9 4.7 23.6 11.1 0.4 0.5 4.9 6.2 1.7 16.0 0.1 1.0 13.0 131.9 0.1 0.2 0.2 0.9 2.0 2.7 8.4 19.1 2.0 17.0 0.0 0.6 0.1 3.3 0.6 0.3 0.5 0.1 0.1 21.5 0.0 0.3 0.2 2.7 3.7 0.0 0.0 0.2 0.1 0.1 63.9 0.0 0.6 0.1 0.0 133.0 0.0 0.0 1.3 0.2 0.3 0.0 1.6 0.0 0.5 0.1 0.3 0.2 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 2.2 0.1 0.1 0.2 0.1 0.6 0.0 0.1 0.0 3.1 38.0 0.3 3.8 0.0 0.1 0.0 3.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.9 15.4 16.5 20.0 12.8 76.3 89.5 42.2 86.7 16.0 131.9 8.4 0.5 9.6 7.2 0.3 0.0 0.3 0.1 0.2 0.0 12.5 10.3 2.3 0.4 1.5 0.0 0.0 6.2 0.0 0.0 0.0 0.0 1.8 2.6 0.3 10.8 0.7 0.0 0.0 0.4 97.8 0.1 29.6 0.0 0.1 251.5 44.1 0.0 0.1 0.1 30.3 17.4 0.0 0.0 0.0 0.4 2.4 6.2 1.2 5.4 1.0 0.0 2.5 0.0 0.0 0.6 16.5 0.0 0.0 0.1 0.1 0.0 0.0 1.5 10.3 0.0 0.2 1.9 1.8 5.0 0.0 0.0 0.1 3.5 70.2 0.0 0.2 CAMKK1 "CAMKKA, DKFZp761M0423, MGC34095" ENSG00000004660 "Calcium/calmodulin dependent protein kinase kinase 1" Q8N5S9 17 3860315-3894891 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 54.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 41.9;Excitatory neurons: 52.7;Rod photoreceptor cells: 25.1" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 5 "amygdala: 21.5;basal ganglia: 24.2;cerebral cortex: 54.4;hippocampal formation: 24.8;white matter: 31.9" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HeLa: 28.3;U-87 MG: 27.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009111, HPA028062" Approved Supported Cytosol No No "Cluster 45: Eosinophils - Innate immune response" "Cluster 10: Brain - Neuronal signaling" "Cluster 20: HeLa - Mitochondria" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "CAB009111: AB_2068406, HPA028062: AB_1845954" "unprognostic (1.39e-2)" "unprognostic (2.13e-1)" "unprognostic (8.66e-3)" "unprognostic (4.40e-3)" "unprognostic (2.94e-3)" "unprognostic (4.79e-2)" "unprognostic (1.98e-1)" "unprognostic (4.47e-3)" "unprognostic (8.23e-2)" "unprognostic (1.03e-2)" "prognostic favorable (2.65e-4)" "unprognostic (1.98e-1)" "unprognostic (1.59e-1)" "unprognostic (7.19e-2)" "unprognostic (8.70e-2)" "unprognostic (8.36e-2)" "unprognostic (3.10e-1)" 6.0 10.7 21.5 5.2 24.2 4.1 5.4 5.6 54.4 12.7 0.0 10.2 2.9 13.1 4.8 6.8 7.0 3.6 5.7 24.8 0.8 3.6 1.0 5.0 2.6 6.0 1.9 8.1 12.7 4.1 24.4 2.0 6.6 8.2 2.7 12.0 29.9 10.4 3.4 15.9 6.9 5.8 0.6 9.6 4.2 10.1 5.0 5.1 7.6 1.6 2.3 16.1 13.8 31.9 7.0 11.8 1.2 5.9 4.1 7.2 0.4 4.7 5.1 4.4 2.0 4.3 2.1 4.2 5.0 9.1 4.6 20.3 3.2 5.8 2.7 0.1 10.7 4.8 28.3 1.6 4.2 0.7 3.6 5.5 4.9 8.4 2.8 3.8 2.0 6.0 3.8 0.2 2.2 1.9 6.0 2.7 1.3 10.1 11.0 3.0 5.1 4.8 4.8 4.4 6.7 3.8 1.8 13.9 3.1 0.7 5.3 1.6 2.8 7.6 10.2 9.9 4.0 0.5 0.3 0.1 27.9 4.0 1.0 0.0 0.9 1.9 0.2 2.0 0.5 0.0 0.3 0.2 0.8 0.0 0.3 0.1 2.7 0.0 2.1 0.4 0.0 0.7 21.5 24.2 5.6 54.4 24.8 0.8 6.0 1.9 6.6 0.6 5.0 31.9 5.5 6.4 12.5 8.1 7.0 3.7 2.1 1.5 1.8 41.9 2.5 1.3 6.3 0.0 3.3 1.8 16.7 0.3 3.4 1.7 0.0 0.4 0.1 1.7 7.8 5.6 4.2 0.4 52.7 1.6 0.1 5.5 0.5 1.6 17.1 0.9 2.9 0.6 4.3 8.4 13.9 1.3 2.0 3.2 3.3 1.3 1.2 6.9 8.8 9.4 0.8 4.7 2.1 4.0 3.5 0.6 0.6 1.2 2.2 2.2 0.2 0.3 1.5 25.1 0.0 2.0 1.7 0.1 1.1 4.1 5.4 0.3 2.9 1.2 2.1 1.1 CAMKMT "C2orf34, CLNMT" ENSG00000143919 "Calmodulin-lysine N-methyltransferase" Q7Z624 2 44361947-44772592 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 155.1;Excitatory neurons: 88.7;Inhibitory neurons: 93.7;Microglial cells: 114.3;Oligodendrocyte precursor cells: 121.2;Oligodendrocytes: 211.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067912 Supported Nucleoplasm NA NA "Cluster 6: Non-specific - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA067912: AB_2685922" "unprognostic (2.28e-1)" "unprognostic (6.15e-2)" "unprognostic (1.96e-1)" "unprognostic (2.39e-2)" "prognostic favorable (9.10e-4)" "unprognostic (1.03e-1)" "unprognostic (9.58e-3)" "unprognostic (1.46e-3)" "unprognostic (1.85e-1)" "unprognostic (7.42e-2)" "unprognostic (8.76e-2)" "unprognostic (1.37e-1)" "unprognostic (3.33e-1)" "unprognostic (4.82e-2)" "unprognostic (4.66e-2)" "unprognostic (1.70e-1)" "unprognostic (8.57e-2)" 4.2 5.3 15.9 3.9 21.1 10.2 5.3 19.4 21.1 5.9 17.8 7.0 5.3 4.1 6.5 6.1 4.9 5.7 5.0 15.5 17.1 7.5 4.8 3.9 5.4 17.7 16.4 3.9 9.8 9.8 5.6 3.3 17.3 3.5 6.8 8.5 4.8 3.9 7.8 5.8 5.7 3.9 15.5 3.7 5.8 13.2 17.9 6.2 7.3 3.3 5.4 4.5 4.7 20.4 10.2 6.2 7.4 6.8 8.0 8.1 15.0 7.4 6.0 4.3 5.5 11.9 9.0 9.6 8.6 5.6 5.3 8.3 10.6 13.2 7.6 35.2 13.3 14.2 12.1 22.4 3.1 9.4 9.5 2.6 8.0 5.9 10.9 6.1 6.4 9.9 10.4 17.1 7.1 10.9 17.6 19.1 13.9 24.6 6.1 10.3 8.3 19.4 20.8 11.6 14.0 13.4 7.6 24.1 9.2 7.0 8.8 7.7 7.6 5.5 6.4 6.1 5.9 13.3 11.5 18.2 6.1 16.5 3.9 13.1 8.2 6.2 11.1 6.9 11.5 20.9 11.2 9.7 9.7 14.7 16.9 13.4 5.2 8.7 8.4 10.1 18.3 6.9 15.9 21.1 19.4 21.1 15.5 17.1 17.7 16.4 17.3 15.5 17.9 20.4 5.4 6.4 3.1 155.1 11.0 5.2 7.9 10.9 9.1 5.3 6.6 5.2 2.2 10.0 5.5 9.2 0.0 3.3 6.9 4.5 23.5 13.3 74.3 8.2 7.2 4.0 0.0 13.3 88.7 15.6 4.5 6.2 11.7 10.0 5.7 2.0 3.3 6.3 5.8 1.7 93.7 5.5 20.3 1.9 4.9 39.0 8.1 4.3 10.6 114.3 6.4 20.3 13.4 121.2 211.7 8.6 8.3 5.7 13.3 5.8 7.2 14.5 7.4 3.0 0.0 3.6 5.0 35.5 5.8 10.7 7.4 2.6 9.2 7.9 8.1 6.0 CAMTA2 KIAA0909 ENSG00000108509 "Calmodulin binding transcription activator 2" O94983 17 4967992-4987675 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Late spermatids: 54.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027835, HPA051147" Supported "Nucleoplasm,Vesicles,Actin filaments,Mitochondria,Cytosol" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "Vesicles, Actin filaments, Mitochondria, Cytosol" "HPA027835: , HPA051147: AB_2681362" "unprognostic (2.82e-1)" "unprognostic (3.06e-1)" "unprognostic (1.11e-2)" "unprognostic (1.01e-3)" "unprognostic (1.10e-1)" "unprognostic (3.24e-2)" "unprognostic (2.36e-1)" "unprognostic (4.71e-2)" "unprognostic (2.78e-2)" "unprognostic (7.08e-2)" "prognostic favorable (6.00e-8)" "unprognostic (3.42e-2)" "unprognostic (9.02e-2)" "unprognostic (3.73e-2)" "unprognostic (1.20e-1)" "unprognostic (4.56e-2)" "unprognostic (1.19e-1)" 15.8 15.6 10.7 13.6 15.9 10.3 15.0 5.2 36.7 14.8 0.0 19.6 10.3 17.0 4.4 14.4 14.4 8.7 17.7 24.2 3.4 16.0 12.9 18.4 9.7 10.0 4.4 14.8 17.5 19.2 26.0 7.4 8.5 15.1 10.8 10.7 13.9 11.6 38.0 17.4 19.0 14.2 0.5 21.6 18.6 14.5 7.3 10.4 17.0 27.5 9.5 16.0 13.0 18.4 13.2 23.2 4.2 6.1 27.8 19.0 8.6 12.4 13.8 11.6 10.1 5.9 3.6 15.5 11.9 19.7 9.8 13.1 16.2 19.5 6.6 21.8 20.7 9.8 13.3 6.6 15.9 5.8 40.4 13.4 24.0 10.8 17.1 14.0 19.6 11.8 16.2 13.9 11.0 8.8 10.3 3.7 0.6 15.6 9.5 8.9 4.8 6.1 13.1 13.8 5.8 5.1 7.8 14.1 3.8 7.2 12.6 5.6 25.6 9.1 5.3 9.8 20.6 6.8 8.0 5.6 22.4 11.5 9.2 0.5 1.2 0.9 1.3 1.6 1.0 0.6 0.6 1.2 0.7 0.4 0.8 1.0 3.0 0.6 4.9 1.1 0.5 1.4 10.7 15.9 5.2 36.7 24.2 3.4 10.0 4.4 8.5 0.5 7.3 18.4 15.2 3.2 11.3 11.4 9.2 6.9 3.7 11.6 8.6 14.7 11.9 8.9 8.0 12.8 6.9 11.0 10.4 5.9 9.0 16.1 1.9 7.9 30.1 5.9 12.6 10.0 11.4 7.4 17.9 11.2 9.6 12.3 20.4 11.6 13.3 14.7 16.8 15.3 8.5 35.3 15.7 13.9 20.3 16.7 10.2 54.3 10.2 13.1 3.6 4.7 14.9 6.5 12.3 9.0 9.5 10.6 13.9 9.4 9.0 6.3 20.1 15.4 6.1 11.2 13.1 7.9 14.8 7.2 6.9 8.8 10.4 12.4 11.4 14.4 12.2 4.1 CAND2 "KIAA0667, TIP120B, Tp120b" ENSG00000144712 "Cullin associated and neddylation dissociated 2 (putative)" O75155 3 12796472-12871916 "Predicted intracellular proteins" "Transcription, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 135.0" "Cell type enriched" "Detected in many" 4 "Early spermatids: 120.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEK 293: 19.4;REH: 12.4;U-266/84: 9.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005777 Approved Approved "Nuclear bodies,Cytosol" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 29: Early spermatids - Spermatogenesis" "Nuclear bodies" Cytosol "HPA005777: AB_2667431" "unprognostic (6.11e-3)" "unprognostic (3.44e-2)" "unprognostic (1.52e-3)" "unprognostic (6.09e-2)" "unprognostic (4.22e-1)" "unprognostic (2.35e-1)" "unprognostic (1.12e-2)" "unprognostic (1.67e-2)" "unprognostic (2.00e-2)" "unprognostic (9.03e-2)" "unprognostic (6.36e-3)" "unprognostic (1.03e-1)" "unprognostic (4.78e-5)" "unprognostic (1.31e-2)" "unprognostic (2.21e-2)" "unprognostic (1.75e-1)" "unprognostic (2.96e-3)" 3.0 3.2 7.9 0.5 7.9 1.0 1.9 6.4 8.7 4.8 7.6 6.5 0.9 6.4 2.2 2.4 6.2 1.7 25.3 8.0 9.6 2.4 1.6 2.4 0.8 8.0 7.4 5.0 2.4 5.4 8.3 0.8 8.3 3.6 0.7 2.2 3.3 3.0 135.0 1.4 2.3 3.4 6.6 2.2 3.3 15.7 8.8 0.8 3.1 36.2 0.6 4.4 2.7 8.6 0.8 1.6 5.6 0.2 0.2 0.1 0.3 1.4 0.6 3.4 4.1 0.9 0.3 1.0 1.9 0.9 0.9 0.2 6.4 0.1 2.6 1.8 19.4 1.5 2.9 1.4 5.2 0.2 0.1 1.2 0.3 3.1 0.1 3.3 0.7 7.2 5.3 1.0 1.0 3.3 2.6 0.8 3.8 0.4 2.0 12.4 1.2 1.0 0.2 1.5 3.9 4.6 0.1 0.9 1.2 1.1 1.6 6.3 0.4 1.0 0.9 1.0 1.4 1.3 9.9 8.4 0.6 1.2 2.0 0.0 0.0 0.0 0.2 0.0 0.1 0.2 0.1 0.2 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.3 0.1 7.9 7.9 6.4 8.7 8.0 9.6 8.0 7.4 8.3 6.6 8.8 8.6 0.9 3.2 1.1 5.9 0.2 0.4 0.8 0.6 1.8 16.0 0.4 0.5 4.8 1.5 0.7 1.8 10.4 0.2 0.2 0.1 0.0 0.9 120.6 0.4 1.4 1.8 0.0 0.4 19.3 0.0 0.2 2.6 0.5 0.3 0.0 5.6 3.3 2.0 4.2 13.5 25.3 0.0 0.0 0.0 0.8 23.2 4.7 0.4 0.0 4.7 0.0 2.9 1.0 12.1 7.2 0.0 0.0 10.1 0.2 0.5 0.0 0.7 0.3 3.1 0.0 4.1 4.0 1.4 5.3 0.4 0.1 0.1 1.0 9.2 0.0 0.4 CAP2 ENSG00000112186 "Cyclase associated actin cytoskeleton regulatory protein 2" P40123 6 17393505-17557790 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 577.1;tongue: 313.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 126.5;Excitatory neurons: 158.1;Inhibitory neurons: 137.2" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 4 "amygdala: 26.1;basal ganglia: 40.9;cerebral cortex: 87.2;hippocampal formation: 50.2;white matter: 32.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "LHCN-M2: 101.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050530, HPA054147" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA050530: AB_2681159, HPA054147: AB_2682400" "unprognostic (7.27e-2)" "unprognostic (5.71e-3)" "unprognostic (1.63e-2)" "unprognostic (1.55e-1)" "unprognostic (4.86e-1)" "unprognostic (2.23e-2)" "unprognostic (9.94e-2)" "unprognostic (3.58e-2)" "unprognostic (7.72e-2)" "unprognostic (1.65e-1)" "unprognostic (6.43e-2)" "unprognostic (2.30e-1)" "unprognostic (1.59e-1)" "unprognostic (1.06e-2)" "unprognostic (1.47e-1)" "unprognostic (8.05e-2)" "unprognostic (1.75e-3)" 17.8 11.6 26.1 7.6 40.9 0.0 10.7 0.9 87.2 15.4 2.9 32.6 4.1 28.5 17.8 21.7 16.8 11.4 113.6 50.2 11.1 8.7 4.5 4.7 1.7 3.2 3.8 4.5 4.2 7.5 5.1 8.8 2.7 25.1 9.6 9.1 7.7 30.7 577.1 2.6 8.9 42.7 0.0 3.1 9.8 1.5 9.1 3.1 5.5 313.0 2.3 14.5 6.4 32.3 15.5 24.6 44.4 55.1 0.3 0.1 10.4 52.3 42.7 46.6 43.0 8.1 6.9 0.0 48.9 62.1 60.5 8.2 21.3 20.9 66.8 0.1 7.9 0.0 15.4 26.5 4.3 0.0 0.0 3.5 9.9 23.1 10.3 72.3 2.2 0.0 0.0 0.1 101.6 25.2 0.0 0.0 17.0 0.8 15.6 5.2 59.1 1.1 23.6 6.4 6.1 10.9 19.0 59.2 31.3 82.8 65.0 11.2 0.2 36.6 31.6 1.0 47.6 0.0 0.0 0.2 11.7 0.1 48.4 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.1 40.9 0.9 87.2 50.2 11.1 3.2 3.8 2.7 0.0 9.1 32.3 2.0 3.2 1.5 9.8 0.0 1.9 4.3 6.2 5.7 16.4 10.2 8.4 126.5 4.3 5.4 1.8 4.2 16.5 0.0 1.9 3.9 2.7 0.1 13.9 13.7 2.7 6.0 0.0 158.1 0.7 12.2 7.9 0.0 5.8 0.0 22.8 3.9 2.4 2.2 8.4 137.2 1.3 2.0 0.0 2.2 0.0 0.6 0.3 0.0 10.3 0.0 6.3 0.0 16.6 7.2 3.7 1.9 4.9 0.0 1.9 0.0 16.7 33.9 2.2 32.9 25.5 43.4 0.1 3.2 2.1 0.9 37.5 0.3 0.3 1.6 0.6 CAPN11 ENSG00000137225 "Calpain 11" Q9UMQ6 6 44158811-44184401 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "testis: 30.3" "Cell type enhanced" "Detected in some" "Adipocytes: 14.0;Breast myoepithelial cells: 11.8;Early spermatids: 24.7;Late spermatids: 9.8;Spermatocytes: 50.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "NTERA-2: 2.2;TIME: 5.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB018070, HPA030955" Enhanced NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 66: Spermatocytes - Spermatogenesis" "CAB018070: AB_2069481, HPA030955: AB_2673672" "unprognostic (2.20e-2)" "unprognostic (1.87e-1)" "unprognostic (1.64e-2)" "unprognostic (2.75e-1)" "unprognostic (6.22e-2)" "unprognostic (3.34e-2)" "unprognostic (3.99e-2)" "unprognostic (4.57e-2)" "unprognostic (1.29e-1)" "unprognostic (8.96e-2)" "unprognostic (1.01e-1)" "unprognostic (2.13e-1)" "unprognostic (3.62e-6)" "unprognostic (2.38e-2)" "unprognostic (3.51e-1)" "unprognostic (2.27e-2)" "unprognostic (8.89e-2)" 1.6 0.4 0.2 0.3 0.2 0.5 2.3 0.4 0.5 0.8 0.1 0.2 0.0 0.3 0.5 0.2 0.3 0.3 0.3 0.3 0.3 0.2 0.1 0.2 0.4 0.2 0.1 0.0 0.1 0.1 0.0 0.5 0.2 0.3 0.1 0.1 0.4 0.0 0.1 0.8 0.4 0.3 0.1 0.1 0.2 30.3 0.3 2.2 0.3 0.2 0.3 0.4 0.5 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.2 0.2 0.0 0.0 0.0 0.1 2.2 0.0 0.0 0.3 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.1 5.8 0.2 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.2 0.2 0.4 0.5 0.3 0.3 0.2 0.1 0.2 0.1 0.3 0.5 14.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.5 11.8 0.5 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 24.7 0.0 0.0 3.9 0.0 2.7 0.5 0.0 0.0 0.7 0.0 0.2 0.0 0.1 1.1 0.0 1.3 0.0 0.3 0.1 0.0 0.3 0.3 9.8 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.7 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.2 50.0 0.9 0.1 0.0 0.0 0.1 0.1 0.1 0.1 CAPN5 "ADNIV, HTRA3, nCL-3, VRNI" ENSG00000149260 "Calpain 5" O15484 11 77066961-77126155 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 60.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 170.3;Gastric mucus-secreting cells: 80.0;Intestinal goblet cells: 89.8;Paneth cells: 72.6;Proximal enterocytes: 75.6;Undifferentiated cells: 69.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.3" "Lineage enriched" "Detected in single" 4 "T-cells: 1.3" "Cell line enhanced" "Detected in many" "OE19: 106.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033237, HPA072319" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Cytosol "CAB033237: AB_2069673, HPA072319: AB_2686512" "unprognostic (6.81e-3)" "unprognostic (1.31e-1)" "unprognostic (3.36e-2)" "prognostic unfavorable (2.16e-6)" "unprognostic (3.47e-3)" "unprognostic (1.34e-1)" "unprognostic (1.13e-1)" "unprognostic (5.30e-2)" "unprognostic (2.52e-1)" "unprognostic (2.21e-2)" "unprognostic (5.35e-3)" "unprognostic (4.64e-1)" "unprognostic (3.17e-3)" "unprognostic (8.58e-3)" "unprognostic (3.25e-1)" "unprognostic (2.31e-2)" "unprognostic (2.30e-3)" 6.7 12.2 8.5 10.9 7.9 2.7 4.9 6.4 8.6 13.5 3.5 60.5 60.7 10.0 5.7 31.6 10.8 36.3 7.2 8.5 8.7 15.1 52.1 4.8 1.9 11.7 8.2 13.2 5.6 1.0 5.1 2.8 12.5 16.0 49.9 3.8 7.7 8.9 1.6 3.1 52.4 11.3 9.9 3.5 47.9 21.5 7.9 2.8 4.7 1.7 2.7 15.4 10.5 8.1 0.8 12.5 8.6 7.8 32.0 30.4 0.7 11.8 22.9 13.4 10.0 6.9 3.6 0.4 7.7 24.5 14.4 0.5 3.8 1.0 6.4 0.5 0.8 2.1 0.5 0.9 7.9 0.2 0.4 16.1 1.4 22.6 5.2 18.8 14.4 5.1 0.2 0.0 26.9 19.9 1.8 0.3 6.6 106.6 9.3 2.0 27.0 0.4 4.6 16.4 0.5 13.5 1.0 2.7 5.9 5.7 1.7 0.1 23.9 25.4 12.3 34.8 1.3 0.8 1.7 0.1 13.1 0.3 5.7 0.0 0.2 0.0 1.3 0.3 0.1 0.0 0.1 0.5 0.2 0.0 0.6 0.8 0.0 0.0 0.0 0.1 0.0 0.7 8.5 7.9 6.4 8.6 8.5 8.7 11.7 8.2 12.5 9.9 7.9 8.1 1.6 0.0 0.5 4.2 1.0 1.7 0.3 2.2 0.0 3.1 0.5 1.8 1.7 24.3 10.3 23.9 0.0 0.1 3.4 170.3 1.9 10.3 1.1 1.9 5.9 2.4 22.3 5.7 4.6 32.7 0.4 7.6 80.0 3.5 0.0 10.2 2.9 40.4 0.9 1.7 6.7 89.8 10.2 1.6 1.8 1.3 12.5 1.2 7.2 1.0 0.3 5.8 5.2 11.6 0.7 22.4 72.6 4.5 0.9 2.0 75.6 9.9 11.1 2.1 0.0 8.3 4.1 0.5 2.3 2.5 0.9 0.0 1.5 5.3 69.2 2.4 CARF "ALS2CR8, FLJ21579, NYD-SP24" ENSG00000138380 "Calcium responsive transcription factor" Q8N187 2 202912214-202988263 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 66.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034557, HPA043191" Approved Approved "Nucleoli fibrillar center,Vesicles,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 52: Non-specific - Transcription" Vesicles "Nucleoli fibrillar center, Cytosol" "HPA034557: AB_10601663, HPA043191: AB_2732503" "unprognostic (4.63e-2)" "unprognostic (3.11e-1)" "unprognostic (1.30e-1)" "unprognostic (1.93e-2)" "unprognostic (6.09e-2)" "unprognostic (8.65e-3)" "unprognostic (1.12e-1)" "unprognostic (2.13e-3)" "unprognostic (4.39e-2)" "unprognostic (1.10e-1)" "unprognostic (7.58e-3)" "unprognostic (1.08e-1)" "unprognostic (6.12e-2)" "unprognostic (2.00e-1)" "unprognostic (2.22e-1)" "unprognostic (1.09e-1)" "unprognostic (2.55e-2)" 4.5 5.3 4.2 5.7 8.6 5.4 7.7 6.4 5.1 5.9 2.5 5.2 4.5 9.4 9.9 5.5 6.8 6.0 4.9 4.4 5.0 6.8 4.5 5.1 8.8 5.9 6.0 7.9 3.9 7.8 5.1 4.7 6.5 6.7 6.0 16.1 4.6 6.4 4.5 7.4 4.9 6.6 4.6 7.5 6.0 21.5 5.5 9.4 10.6 5.4 7.8 5.7 5.0 12.3 2.5 2.4 6.1 5.4 4.5 9.5 4.7 3.7 4.7 3.8 3.4 2.8 6.2 3.8 1.6 4.3 4.6 4.5 3.2 2.7 4.3 3.0 1.7 5.9 3.0 1.7 3.8 3.5 2.9 7.8 5.2 3.3 8.6 9.6 2.3 13.9 2.5 15.5 5.9 4.9 7.2 5.6 2.6 1.6 3.5 5.1 4.2 3.1 6.9 2.6 4.3 4.6 4.0 2.2 1.7 7.7 3.6 6.5 2.7 7.1 1.8 4.6 2.4 13.7 8.4 4.2 6.1 4.1 4.4 1.4 1.0 0.8 2.2 1.9 2.4 2.0 2.2 2.1 1.2 2.4 3.1 2.2 0.4 8.8 1.1 1.9 4.7 0.6 4.2 8.6 6.4 5.1 4.4 5.0 5.9 6.0 6.5 4.6 5.5 12.3 5.6 9.6 15.7 28.7 14.6 3.2 3.9 5.5 5.2 33.5 6.7 5.5 6.6 7.2 14.1 14.7 18.8 4.2 9.2 2.7 11.7 4.4 19.0 7.1 5.0 5.6 1.8 7.6 21.5 2.4 9.3 7.4 5.6 2.9 20.3 19.6 8.2 3.2 3.9 26.9 25.0 4.7 6.1 8.2 3.7 16.7 10.8 4.9 1.8 16.9 5.9 9.6 18.6 39.2 66.1 2.9 3.2 9.4 4.0 2.0 9.5 5.8 17.7 31.1 6.6 7.1 5.6 37.2 8.6 4.4 2.7 1.8 10.2 10.5 6.2 2.7 CARMIL1 "CARMIL, dJ501N12.1, FLJ20048, LRRC16, LRRC16A" ENSG00000079691 "Capping protein regulator and myosin 1 linker 1" Q5VZK9 6 25279078-25620530 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 27.9;Collecting duct cells: 35.0;Distal tubular cells: 46.9;Endometrial ciliated cells: 37.3;Glandular and luminal cells: 39.3;Granulosa cells: 31.8;Proximal tubular cells: 58.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RPMI-8226: 36.0;RPTEC TERT1: 34.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029038, HPA029039" Enhanced Supported Cytosol NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 50: Fibroblasts - ECM organization" Cytosol "HPA029038: AB_10601668, HPA029039: AB_10611382" "unprognostic (2.34e-2)" "unprognostic (9.45e-2)" "unprognostic (2.07e-2)" "unprognostic (4.71e-2)" "unprognostic (3.94e-2)" "unprognostic (2.22e-1)" "unprognostic (1.66e-3)" "unprognostic (3.82e-1)" "unprognostic (4.02e-1)" "unprognostic (7.15e-3)" "unprognostic (8.25e-3)" "unprognostic (5.86e-2)" "unprognostic (1.28e-3)" "unprognostic (3.08e-2)" "unprognostic (2.53e-1)" "unprognostic (1.07e-1)" "unprognostic (2.31e-1)" 4.4 3.9 2.7 2.8 4.1 0.7 6.5 6.4 5.9 5.2 0.0 10.7 15.3 2.5 7.1 4.3 5.5 5.8 3.7 2.2 2.5 8.5 2.1 8.0 3.6 1.0 3.5 4.3 4.5 5.1 1.2 4.6 0.8 3.3 10.0 1.0 5.3 2.7 0.4 5.9 15.8 2.7 1.3 2.8 7.4 11.4 3.2 7.6 5.2 2.0 3.7 5.2 3.7 1.2 12.9 12.7 3.5 4.5 3.2 1.6 12.1 4.3 9.7 4.5 7.9 13.7 9.4 4.4 13.8 6.9 13.2 13.7 13.6 12.2 3.3 11.1 7.2 10.7 14.0 1.7 8.9 0.5 1.6 1.7 8.2 8.7 13.3 5.6 0.2 1.6 0.3 3.5 2.9 10.0 0.7 0.0 4.8 22.7 5.2 1.5 2.1 36.0 34.7 11.5 9.0 1.9 19.1 32.4 12.4 10.1 7.8 0.3 0.2 3.3 5.8 15.8 4.4 0.5 0.2 7.0 5.2 3.9 12.6 0.0 0.4 0.0 0.0 0.5 0.0 0.2 0.1 0.1 0.4 1.3 1.0 0.1 0.0 0.6 1.3 0.9 0.0 0.1 2.7 4.1 6.4 5.9 2.2 2.5 1.0 3.5 0.8 1.3 3.2 1.2 3.2 19.2 27.9 0.0 7.7 0.0 0.0 0.0 0.0 0.0 17.5 11.6 0.0 0.0 4.3 35.0 0.0 20.8 0.4 0.0 46.9 16.7 0.0 37.3 7.0 4.0 0.0 0.0 0.0 15.6 7.9 12.8 0.0 39.3 8.8 31.8 0.0 0.0 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 3.6 0.0 0.0 0.0 0.0 17.6 0.0 0.0 7.6 0.0 0.0 58.8 3.6 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 10.9 1.6 14.9 0.0 0.0 CARNMT1 "C9orf41, FLJ25795" ENSG00000156017 "Carnosine N-methyltransferase 1" Q8N4J0 9 74980790-75028423 "Enzymes, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 5 "Early spermatids: 256.8" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 24.6" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026756 Uncertain NA NA "Cluster 35: T-regs - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 32: U-937 - Innate immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA026756: AB_1845824" "unprognostic (1.59e-1)" "unprognostic (1.02e-1)" "unprognostic (2.99e-2)" "unprognostic (4.81e-2)" "unprognostic (3.48e-1)" "unprognostic (1.56e-1)" "unprognostic (3.22e-2)" "unprognostic (4.92e-2)" "unprognostic (3.94e-2)" "unprognostic (1.15e-1)" "unprognostic (2.42e-2)" "unprognostic (1.54e-1)" "unprognostic (1.25e-2)" "unprognostic (1.45e-2)" "unprognostic (3.00e-1)" "unprognostic (1.85e-1)" "unprognostic (4.62e-2)" 5.1 6.1 1.8 7.0 13.8 8.3 7.0 24.6 6.0 5.8 0.1 9.2 12.7 6.1 8.3 10.0 6.2 6.8 5.4 3.7 0.4 12.2 17.1 5.4 9.7 0.1 2.5 6.1 9.0 11.3 3.9 5.3 1.8 6.4 8.5 7.8 9.1 5.3 8.7 8.4 12.4 6.1 0.2 6.7 7.8 16.4 1.0 8.4 13.6 8.5 8.5 9.1 5.1 3.5 27.6 16.1 6.6 17.0 10.3 22.4 24.6 24.4 10.0 9.0 8.2 4.1 17.9 43.7 12.9 17.4 19.2 26.7 20.0 25.3 25.5 40.0 17.4 22.3 15.5 18.4 12.6 40.7 21.2 15.0 12.4 17.0 17.3 13.3 18.6 15.6 19.1 36.9 17.4 7.3 29.8 10.8 31.4 33.0 14.7 14.4 20.2 25.4 23.5 19.0 6.5 3.6 18.7 46.2 9.2 11.8 23.5 11.7 14.8 14.8 19.9 18.2 21.3 28.2 38.3 13.1 22.9 27.6 9.8 0.0 0.4 1.0 1.3 0.8 1.9 1.7 1.3 2.0 0.6 0.9 1.6 1.5 0.1 1.5 0.4 0.6 2.0 0.7 1.8 13.8 24.6 6.0 3.7 0.4 0.1 2.5 1.8 0.2 1.0 3.5 8.5 6.4 11.7 0.0 10.2 0.0 11.6 0.0 21.6 14.5 16.6 8.0 0.0 11.5 6.8 27.6 10.4 7.0 18.6 4.5 25.4 7.5 256.8 11.2 19.6 9.4 7.3 6.3 0.0 11.9 13.0 6.6 13.7 14.8 2.5 8.7 8.9 29.8 8.1 20.2 0.0 12.8 0.0 9.1 0.0 44.3 7.5 8.5 0.0 0.0 8.9 5.6 17.5 0.0 0.0 9.3 8.8 10.9 17.4 17.7 22.6 37.3 4.4 10.4 0.0 9.3 5.6 17.7 10.3 33.5 0.0 5.1 17.1 16.2 13.2 15.0 CASP14 "MGC119078, MGC119079, MICE" ENSG00000105141 "Caspase 14" P31944 19 15049480-15058293 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Differentiation "Hydrolase, Protease, Thiol protease" Ichthyosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 24 "skin 1: 486.0" "Cell type enriched" "Detected in some" 5 "Suprabasal keratinocytes: 96.0" "Cancer enhanced" "Detected in many" "cervical cancer: 62.8" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "hTCEpi: 49.0" "Not detected" "Not detected" "Not detected" "Not detected" "CAB010059, HPA027062" Enhanced Supported Nucleoplasm,Mitochondria,Cytosol NA NA 3600000 "Cluster 61: Skin - Cornification" "Cluster 30: Epithelial cell lines - Translation" "Cluster 28: Keratinocytes - Keratinization" "Nucleoplasm, Cytosol" Mitochondria "CAB010059: AB_626800, HPA027062: AB_2672101" "unprognostic (1.17e-2)" "unprognostic (6.44e-3)" "unprognostic (6.22e-2)" "unprognostic (2.77e-1)" "prognostic unfavorable (7.59e-4)" "unprognostic (9.42e-2)" "unprognostic (2.19e-2)" "prognostic unfavorable (5.96e-4)" "unprognostic (2.68e-1)" "unprognostic (4.30e-2)" "unprognostic (1.99e-1)" "unprognostic (1.97e-1)" 0.6 0.0 0.1 0.0 0.4 0.4 7.8 0.4 0.2 3.9 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.2 0.1 0.1 0.1 0.1 0.0 0.3 0.1 0.0 0.6 0.1 0.0 0.0 0.3 0.8 0.0 0.1 1.1 4.2 1.4 486.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 1.0 0.0 0.0 0.0 0.0 19.9 1.0 1.1 0.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 49.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.9 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.4 0.2 0.2 0.1 0.3 0.1 0.3 0.0 0.3 1.0 0.0 0.0 0.0 0.0 0.0 19.1 1.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.4 2.8 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 96.0 0.7 0.1 0.0 0.0 0.8 CATSPER2 ENSG00000166762 "Cation channel sperm associated 2" Q96P56 15 43628503-43668118 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Differentiation, Ion transport, Spermatogenesis, Transport" "Calcium channel, Developmental protein, Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 14.6;retina: 22.8;testis: 15.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 254.4;Early spermatids: 73.6;Rod photoreceptor cells: 221.8;Spermatocytes: 117.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 14.6" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HeLa: 11.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 37: B-cells - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 9: Photoreceptor cells - Phototransduction" "unprognostic (6.88e-3)" "unprognostic (6.79e-2)" "unprognostic (2.08e-2)" "unprognostic (2.65e-2)" "unprognostic (4.05e-1)" "unprognostic (1.05e-2)" "unprognostic (7.11e-3)" "unprognostic (1.48e-2)" "unprognostic (6.35e-2)" "unprognostic (1.15e-2)" "unprognostic (1.09e-2)" "unprognostic (3.37e-2)" "unprognostic (3.74e-3)" "unprognostic (1.15e-1)" "unprognostic (6.04e-2)" "unprognostic (8.87e-2)" "unprognostic (8.23e-5)" 1.2 1.4 2.0 0.8 2.2 4.2 1.8 14.6 4.0 1.3 0.1 2.3 3.3 1.4 5.4 2.4 1.4 0.7 0.9 2.2 0.7 1.4 1.5 1.2 2.0 1.4 0.6 1.6 1.2 4.0 3.2 0.8 1.7 1.6 2.3 22.8 1.6 2.2 1.2 5.4 3.8 0.6 0.1 1.5 1.8 15.5 0.9 0.9 1.9 1.5 1.5 1.7 1.3 3.1 2.0 2.8 1.2 4.4 0.0 0.0 2.0 0.7 1.7 1.2 2.9 0.7 1.1 2.4 1.0 0.5 1.4 4.4 1.1 3.9 1.2 2.0 5.4 7.0 11.2 1.0 1.8 1.6 2.2 0.2 3.0 1.7 4.3 3.2 1.5 4.3 2.8 2.4 0.4 0.5 1.3 2.8 0.4 2.7 1.2 1.9 1.4 1.1 2.4 3.2 2.6 0.9 1.1 1.6 0.1 1.6 3.2 1.5 0.4 3.0 1.3 0.0 1.8 0.4 0.3 5.1 2.1 4.9 1.1 0.1 0.3 0.1 0.3 0.1 0.4 1.1 0.2 0.4 0.2 0.3 0.3 0.7 0.5 0.5 0.3 0.4 0.1 0.0 2.0 2.2 14.6 4.0 2.2 0.7 1.4 0.6 1.7 0.1 0.9 3.1 4.8 0.0 4.5 0.0 4.9 7.0 8.2 8.3 1.8 56.7 6.9 6.9 4.2 5.7 8.0 7.3 254.4 6.0 6.0 3.9 3.9 3.2 73.6 5.2 2.5 6.0 21.5 2.7 0.0 2.7 2.1 3.2 6.1 4.2 9.5 29.7 8.6 3.9 4.3 38.7 0.0 4.6 4.1 5.0 6.5 37.4 6.2 4.5 1.8 0.0 4.5 13.4 7.2 0.0 0.0 2.0 3.3 7.2 1.1 6.7 11.1 4.1 10.8 221.8 0.0 9.3 5.1 117.4 17.1 2.7 8.0 3.0 4.6 5.8 8.5 8.4 CATSPERB "C14orf161, FLJ14298" ENSG00000133962 "Cation channel sperm associated auxiliary subunit beta" Q9H7T0 14 91580696-91780707 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "pancreas: 10.7" "Cell type enhanced" "Detected in some" "Early spermatids: 22.9;Exocrine glandular cells: 10.9;Gastric mucus-secreting cells: 11.7;Glandular and luminal cells: 6.2;Pancreatic endocrine cells: 7.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 1.2;OE19: 1.3;U-937: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA035134 Uncertain Vesicles NA NA "Cluster 38: Basophils - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 32: U-937 - Innate immune response" "Cluster 29: Early spermatids - Spermatogenesis" Vesicles "HPA035134: AB_10671510" "unprognostic (2.69e-2)" "unprognostic (1.95e-1)" "unprognostic (1.16e-3)" "unprognostic (1.93e-1)" "unprognostic (7.04e-3)" "unprognostic (2.72e-5)" "unprognostic (1.81e-1)" "unprognostic (5.01e-3)" "unprognostic (1.81e-3)" "unprognostic (3.52e-3)" "unprognostic (2.30e-2)" "unprognostic (4.34e-1)" "unprognostic (8.99e-3)" "unprognostic (6.85e-2)" "unprognostic (8.31e-2)" "unprognostic (8.88e-2)" "unprognostic (2.71e-3)" 0.5 0.2 0.5 0.6 0.5 0.3 0.8 1.0 0.5 0.4 0.1 0.6 0.4 0.2 0.4 0.5 0.4 0.8 0.4 0.3 0.2 0.2 0.1 0.6 0.9 0.3 0.1 0.3 10.7 0.3 0.2 0.2 0.3 0.6 0.5 0.8 2.5 0.2 1.2 2.3 0.9 0.2 0.1 0.6 1.4 1.1 0.2 0.3 0.5 0.0 0.5 0.2 0.2 0.8 0.2 0.0 0.2 0.5 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.7 1.2 0.4 0.3 0.0 0.0 0.2 0.0 0.1 0.2 0.4 0.6 0.1 0.4 0.7 0.0 0.5 0.2 0.1 0.2 0.1 0.1 0.5 0.0 0.3 0.1 0.0 0.1 0.7 0.2 0.2 0.0 1.3 0.1 0.1 0.0 0.0 0.1 0.3 0.5 0.0 0.0 0.2 0.5 0.5 0.1 0.7 0.3 0.0 0.0 0.0 0.1 0.2 0.3 0.1 0.0 1.2 0.3 0.3 0.0 0.1 0.1 0.0 0.2 0.1 0.2 0.1 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.5 1.0 0.5 0.3 0.2 0.3 0.1 0.3 0.1 0.2 0.8 0.1 3.2 1.5 0.3 0.1 0.1 0.3 0.2 0.0 0.0 3.3 1.0 0.2 0.0 2.1 0.0 0.0 0.1 0.3 2.2 0.0 2.7 22.9 1.6 0.9 0.6 0.0 0.0 4.9 10.9 0.1 0.6 11.7 6.2 0.0 0.1 0.0 0.1 0.0 0.0 1.3 3.0 0.0 0.3 0.3 3.2 0.6 0.1 0.0 1.9 0.6 0.0 1.0 0.5 1.8 7.5 2.5 0.0 0.4 0.9 0.1 0.5 1.5 0.0 0.0 0.9 0.3 4.5 0.2 0.8 0.0 0.3 0.7 0.1 1.4 0.8 CAV3 "LGMD1C, LQT9, VIP-21, VIP21" ENSG00000182533 "Caveolin 3" P56539 3 8733802-8841808 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cardiomyopathy, Disease variant, Limb-girdle muscular dystrophy, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "skeletal muscle: 182.7;tongue: 72.8" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 22.9;Early spermatids: 4.2;Sertoli cells: 6.6;Skeletal myocytes: 11.0" "Cancer enhanced" "Detected in single" "head and neck cancer: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "RH-30: 94.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB017518, CAB018557, HPA054488" Enhanced Approved "Vesicles,Plasma membrane" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane" Vesicles "CAB017518: AB_628860, CAB018557: AB_626814, HPA054488: AB_2682504" "unprognostic (1.79e-1)" "unprognostic (1.43e-1)" "unprognostic (1.40e-2)" "unprognostic (6.43e-2)" "unprognostic (8.79e-2)" "unprognostic (3.05e-3)" "unprognostic (8.38e-3)" "unprognostic (9.79e-2)" "unprognostic (1.36e-1)" 0.4 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.2 5.7 0.1 0.1 27.4 0.1 0.1 0.0 0.0 0.9 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 1.9 0.1 0.0 2.5 0.2 182.7 0.2 0.1 0.0 0.0 0.1 0.1 0.4 0.1 0.2 0.1 72.8 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 94.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 22.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.5 0.3 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 11.0 2.3 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 CBLN4 "CBLNL1, dJ885A10.1" ENSG00000054803 "Cerebellin 4 precursor" Q9NTU7 20 55997357-56005519 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 17.8;brain: 19.3;epididymis: 8.8" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 8.9;Excitatory neurons: 26.9;Inhibitory neurons: 31.6;Peritubular cells: 38.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 50 "SH-SY5Y: 9.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA074497 Supported "Secreted in brain" NA NA 10000000 "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA074497: " "unprognostic (3.61e-1)" "unprognostic (8.43e-3)" "unprognostic (2.43e-1)" "unprognostic (1.61e-2)" "unprognostic (1.99e-1)" "unprognostic (4.00e-1)" "unprognostic (3.25e-1)" "unprognostic (2.11e-1)" "unprognostic (1.42e-1)" "unprognostic (3.88e-1)" "unprognostic (9.63e-2)" "unprognostic (1.74e-1)" "unprognostic (1.40e-3)" "unprognostic (3.22e-4)" "unprognostic (7.50e-2)" "unprognostic (3.58e-2)" "unprognostic (1.79e-3)" 1.6 17.8 14.6 0.1 3.4 0.0 1.4 0.0 9.4 1.9 0.0 0.0 0.0 0.7 8.8 0.1 3.8 0.5 0.0 14.4 5.8 0.6 0.9 0.7 0.0 0.7 19.3 2.0 0.7 0.3 0.1 0.2 2.4 0.1 0.0 0.3 0.1 0.3 0.3 0.0 0.1 0.3 0.0 0.0 0.3 2.0 12.2 0.1 0.9 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 3.4 0.0 9.4 14.4 5.8 0.7 19.3 2.4 0.0 12.2 0.2 0.1 0.0 0.0 2.9 0.0 0.0 0.1 0.0 0.0 0.9 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.1 0.2 8.9 0.0 26.9 0.0 0.0 5.2 0.0 0.1 0.0 0.0 0.0 1.3 0.1 1.7 31.6 0.0 0.0 0.0 0.0 1.0 2.1 0.2 0.0 1.9 0.0 0.2 0.0 1.0 2.0 0.0 0.0 38.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.5 0.9 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 CBX1 "CBX, HP1-BETA, HP1Hs-beta, M31, MOD1" ENSG00000108468 "Chromobox 1" P83916 17 48070052-48101478 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 350.8;Spermatogonia: 304.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB012265 Supported Supported "Nucleoplasm,Nuclear bodies" NA NA 120000 "Cluster 1: Neutrophils - Mixed function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoplasm, Nuclear bodies" "CAB012265: AB_297216" "unprognostic (7.50e-2)" "unprognostic (3.33e-1)" "unprognostic (2.02e-1)" "unprognostic (2.58e-2)" "unprognostic (3.15e-1)" "unprognostic (3.04e-1)" "prognostic unfavorable (2.70e-4)" "unprognostic (2.68e-2)" "unprognostic (3.45e-2)" "unprognostic (6.55e-2)" "unprognostic (2.78e-1)" "unprognostic (2.72e-2)" "unprognostic (1.67e-2)" "unprognostic (6.48e-3)" "unprognostic (3.82e-1)" "unprognostic (3.65e-1)" "unprognostic (6.73e-2)" 30.9 31.4 60.3 35.5 59.9 16.5 37.2 61.6 73.2 53.6 54.5 40.7 19.0 66.5 47.9 36.8 40.2 27.9 32.1 59.8 63.9 37.9 21.6 26.9 35.0 63.2 59.7 77.5 22.3 43.8 34.8 34.7 64.0 38.0 33.1 59.5 29.7 47.1 68.4 28.8 24.0 55.6 64.9 33.7 26.6 69.1 60.3 73.6 39.5 46.0 46.9 36.4 37.9 67.3 217.3 121.1 392.4 185.6 78.0 69.3 217.7 197.0 95.1 188.0 200.6 319.2 84.5 148.4 204.5 155.6 144.8 85.3 146.3 124.6 329.2 273.8 118.1 119.8 121.1 119.3 47.5 115.5 71.9 49.8 68.4 140.3 178.3 144.7 157.1 176.6 152.0 67.2 153.8 135.7 325.9 79.8 150.6 118.8 156.9 241.8 322.7 95.8 110.3 121.7 138.5 345.6 135.0 44.6 75.5 281.8 211.0 82.5 110.7 260.2 238.9 112.0 201.1 94.0 227.9 140.4 71.4 50.4 119.0 5.1 12.2 16.0 12.4 12.7 10.0 16.1 11.2 10.4 9.9 15.7 11.5 9.7 33.6 9.5 9.3 10.6 12.4 5.9 60.3 59.9 61.6 73.2 59.8 63.9 63.2 59.7 64.0 64.9 60.3 67.3 32.9 67.3 27.6 7.8 31.4 43.6 30.5 46.1 36.5 46.9 48.0 54.7 70.9 18.6 33.6 42.3 20.9 66.4 27.5 19.2 35.2 68.7 26.8 40.8 78.9 40.2 40.3 34.3 13.0 29.7 86.6 61.5 10.2 39.6 39.9 65.3 30.0 15.6 69.6 50.5 15.5 27.3 42.7 33.5 24.5 59.5 80.2 26.7 40.9 7.5 47.7 106.6 42.2 12.5 13.7 34.7 12.9 91.7 20.0 51.1 9.6 30.9 32.2 36.3 39.5 33.3 71.8 350.8 304.0 26.7 36.2 27.8 25.6 35.8 28.6 20.1 CBX4 "hPC2, NBP16, PC2" ENSG00000141582 "Chromobox 4" O00257 17 79833156-79839440 "Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Chromatin regulator, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "bone marrow: 130.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "SK-BR-3: 110.8;SK-MEL-30: 130.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008228, HPA012021" Approved Enhanced "Nucleoplasm,Nuclear bodies" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Nuclear bodies" "HPA008228: AB_1078413, HPA012021: AB_2668603" "unprognostic (1.30e-1)" "unprognostic (1.15e-1)" "unprognostic (1.72e-2)" "unprognostic (1.86e-1)" "unprognostic (3.97e-2)" "unprognostic (8.80e-2)" "unprognostic (5.39e-3)" "unprognostic (1.49e-1)" "unprognostic (2.55e-1)" "unprognostic (1.40e-2)" "unprognostic (7.62e-2)" "unprognostic (2.34e-3)" "prognostic unfavorable (8.72e-8)" "unprognostic (7.49e-2)" "unprognostic (2.87e-1)" "unprognostic (3.99e-2)" "unprognostic (1.07e-1)" 9.3 14.2 9.6 11.1 10.8 130.3 9.0 8.8 12.5 9.1 0.0 7.9 7.1 6.3 4.6 20.7 8.1 6.3 16.0 12.4 9.7 10.6 21.6 12.3 14.6 11.5 9.5 9.6 19.0 17.0 19.1 15.2 10.7 9.3 3.2 12.3 13.2 4.6 3.4 31.6 11.9 3.8 8.2 20.9 12.9 6.9 12.2 23.1 8.6 1.4 7.2 6.7 10.3 16.6 32.1 28.3 8.4 36.3 5.2 4.7 23.5 14.3 8.5 5.1 5.4 20.5 17.5 12.3 19.7 5.6 11.4 16.3 9.3 9.5 3.8 13.3 17.7 7.0 28.0 38.4 25.4 37.0 52.5 6.5 54.4 4.7 8.4 8.5 4.3 35.5 21.7 67.5 5.5 23.0 50.9 37.7 4.6 33.2 28.2 51.9 8.6 56.3 7.2 15.3 8.7 16.6 21.4 110.8 130.9 3.5 26.3 58.3 11.2 29.8 26.3 18.4 18.6 58.0 32.4 35.0 18.7 31.6 40.4 1.6 0.5 1.8 0.9 0.6 0.6 1.5 1.2 1.3 0.3 1.5 1.4 1.3 2.1 0.4 0.7 1.7 0.2 0.6 9.6 10.8 8.8 12.5 12.4 9.7 11.5 9.5 10.7 8.2 12.2 16.6 40.4 3.2 15.7 4.6 31.8 23.3 5.4 13.4 36.5 31.7 65.2 79.8 51.6 30.0 12.1 1.8 22.9 34.2 77.6 26.6 0.0 7.5 0.2 63.9 19.3 21.6 52.7 7.8 5.5 7.3 5.0 15.8 20.9 62.8 7.0 22.3 15.7 16.3 13.8 20.2 5.5 49.5 2.0 19.8 17.0 1.0 4.4 35.4 17.8 12.2 15.4 39.2 15.5 6.0 11.6 10.0 18.4 5.7 26.1 6.3 9.6 2.8 14.6 44.3 6.6 15.3 24.4 0.5 2.4 65.7 30.7 8.6 42.5 13.7 29.7 5.2 CC2D2B "bA248J23.4, bA690P14.3, C10orf130, C10orf131" ENSG00000188649 "Coiled-coil and C2 domain containing 2B" Q6DHV5 10 95907603-96033745 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "testis: 8.7" "Cell type enhanced" "Detected in some" "Astrocytes: 25.8;Early spermatids: 10.8;Microglial cells: 15.0;Oligodendrocyte precursor cells: 13.6;Oligodendrocytes: 7.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA044091, HPA072122" Enhanced Approved "Nucleoli,Nucleoli rim" NA NA "Cluster 37: B-cells - Transcription" "Cluster 78: Testis - Spermatogenesis" "Cluster 16: U-266 - Nucleosome" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoli, Nucleoli rim" "HPA044091: AB_2732514, HPA072122: AB_2686489" "unprognostic (6.38e-2)" "unprognostic (5.95e-2)" "unprognostic (1.47e-1)" "unprognostic (5.00e-2)" "unprognostic (1.36e-1)" "unprognostic (1.19e-2)" "unprognostic (1.04e-1)" "unprognostic (2.39e-3)" "unprognostic (1.21e-1)" "unprognostic (3.63e-1)" "unprognostic (8.18e-3)" "unprognostic (2.11e-3)" "unprognostic (9.11e-4)" "unprognostic (1.93e-2)" "unprognostic (4.34e-1)" "unprognostic (5.45e-3)" "unprognostic (1.41e-1)" 0.7 1.9 0.9 1.9 2.7 2.5 0.5 1.2 1.6 0.8 3.4 0.9 1.0 1.5 0.4 0.8 0.9 1.5 1.1 0.5 3.5 0.9 0.6 0.8 1.3 2.1 0.9 1.1 0.4 0.7 0.3 1.1 2.6 0.6 0.3 2.8 1.0 0.4 2.2 2.4 0.6 1.2 1.0 1.2 1.0 8.7 2.2 0.2 3.0 0.2 0.2 0.8 0.8 5.4 1.1 4.4 3.7 7.4 0.2 0.4 4.1 3.8 0.4 0.7 0.1 3.3 0.8 4.4 3.0 0.0 3.8 3.0 0.3 0.3 0.0 4.9 8.5 9.7 3.5 2.8 0.0 9.8 0.7 0.7 0.0 0.4 0.1 1.3 0.3 1.4 7.8 2.9 0.9 2.6 4.6 3.1 7.9 3.3 6.8 12.1 3.4 3.8 0.7 0.8 6.5 3.2 3.9 1.0 2.5 4.4 6.8 4.9 3.7 4.3 4.5 3.0 5.7 2.6 11.7 0.2 3.3 8.4 2.8 0.0 0.3 0.0 0.5 0.1 0.9 1.2 0.4 0.3 0.3 1.2 0.4 0.1 0.3 0.2 0.2 0.3 0.2 0.1 0.9 2.7 1.2 1.6 0.5 3.5 2.1 0.9 2.6 1.0 2.2 5.4 1.1 0.0 0.0 25.8 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 10.8 0.2 0.4 1.1 0.0 0.0 3.2 0.0 0.0 0.3 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 2.5 0.0 0.5 0.0 15.0 0.2 0.0 0.0 13.6 7.0 0.0 0.0 0.0 0.1 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 CCDC106 HSU79303 ENSG00000173581 "Coiled-coil domain containing 106" Q9BWC9 19 55641062-55653161 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 69.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 9.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEK 293: 82.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041925, HPA043219" Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm Cytosol "HPA041925: AB_2677750, HPA043219: AB_2678368" "unprognostic (5.74e-3)" "unprognostic (1.34e-1)" "unprognostic (1.71e-1)" "unprognostic (5.16e-2)" "unprognostic (9.19e-2)" "unprognostic (2.82e-1)" "unprognostic (8.11e-2)" "unprognostic (1.21e-2)" "unprognostic (4.88e-2)" "unprognostic (8.74e-2)" "prognostic favorable (2.23e-6)" "unprognostic (2.28e-1)" "prognostic favorable (7.54e-11)" "unprognostic (5.03e-2)" "unprognostic (7.88e-2)" "unprognostic (3.26e-1)" "unprognostic (8.69e-2)" 12.0 21.7 27.8 5.1 32.7 2.6 11.9 20.4 37.6 11.4 17.7 18.7 4.1 13.4 6.4 8.0 13.3 6.5 21.9 33.0 22.4 29.1 24.3 9.4 10.3 21.8 23.1 12.7 9.8 13.6 27.3 5.1 21.1 15.2 2.7 6.5 11.1 11.2 24.5 9.3 13.7 7.1 18.4 18.2 13.7 20.8 23.5 4.7 16.7 20.2 9.0 12.8 8.3 24.7 8.7 33.6 14.4 25.3 10.1 9.6 2.0 7.4 12.9 25.0 21.0 7.3 13.2 25.6 5.6 13.8 0.7 7.3 24.6 16.0 7.1 1.3 82.2 26.7 23.4 13.3 30.1 1.8 14.3 15.6 1.9 5.9 1.4 17.4 8.0 16.0 20.1 15.7 12.5 2.3 16.3 10.8 6.9 0.8 18.3 25.5 7.3 17.7 25.9 0.8 15.8 29.4 5.9 41.3 14.7 8.5 17.9 17.3 9.0 7.7 7.9 0.7 5.5 9.3 3.5 33.0 20.7 8.4 0.6 0.0 2.3 0.0 0.4 1.5 1.4 7.2 0.4 0.6 2.9 9.6 3.1 1.9 0.0 0.8 0.1 8.9 0.3 1.7 27.8 32.7 20.4 37.6 33.0 22.4 21.8 23.1 21.1 18.4 23.5 24.7 12.0 0.0 1.3 8.8 18.1 2.5 6.0 14.0 12.0 22.3 16.0 17.1 23.8 11.5 6.5 20.2 4.2 13.5 6.8 4.6 41.1 19.6 4.0 3.9 7.2 10.8 4.9 4.2 6.4 7.2 15.0 9.7 11.7 3.3 8.9 10.5 10.0 17.5 17.5 37.0 6.4 8.7 8.2 9.4 6.4 2.7 14.0 7.9 3.6 3.7 11.7 34.1 3.1 4.5 3.6 8.7 8.0 18.8 7.0 6.0 10.6 69.4 3.2 9.7 13.1 9.3 9.0 4.7 30.2 10.3 3.7 8.8 3.9 18.9 6.0 5.7 CCDC110 "CT52, KM-HN-1, MGC33607" ENSG00000168491 "Coiled-coil domain containing 110" Q8TBZ0 4 185445182-185471752 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "pancreas: 30.7;testis: 100.0" "Cell type enhanced" "Detected in many" "Early spermatids: 796.2;Late spermatids: 175.5;Spermatocytes: 552.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SCLC-21H: 8.4;U-266/70: 5.3;U-266/84: 8.8;U-87 MG: 4.0" "Low region specificity" "Detected in many" HPA078808 Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 16: U-266 - Nucleosome" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Golgi apparatus" "HPA078808: " "unprognostic (1.18e-1)" "unprognostic (7.26e-3)" "unprognostic (5.42e-2)" "unprognostic (9.84e-4)" "unprognostic (3.72e-2)" "unprognostic (3.08e-3)" "unprognostic (1.95e-5)" "unprognostic (4.92e-2)" "unprognostic (5.81e-2)" "unprognostic (9.94e-3)" "unprognostic (1.43e-1)" "unprognostic (2.64e-1)" "prognostic favorable (1.08e-5)" "unprognostic (1.37e-1)" "unprognostic (1.84e-1)" "unprognostic (1.21e-2)" "unprognostic (1.21e-2)" 0.6 1.0 1.8 1.0 3.4 0.0 3.6 2.6 2.1 2.6 1.6 1.8 0.9 1.4 5.1 1.8 2.9 1.2 1.1 1.2 1.2 2.5 0.8 0.9 1.2 2.0 1.6 4.5 30.7 2.0 2.9 0.8 2.4 2.2 1.9 7.9 6.2 2.0 2.1 1.1 0.8 1.4 0.8 0.6 2.5 100.0 1.7 0.4 7.7 0.9 0.7 1.3 0.5 0.9 0.4 0.0 0.2 0.1 2.2 2.4 0.1 0.0 0.0 0.0 0.2 0.0 1.7 2.7 0.3 0.0 2.3 0.3 1.7 0.0 0.2 1.0 1.7 0.0 0.2 0.0 1.1 0.0 0.0 0.6 0.0 1.0 0.0 1.4 0.8 0.7 0.2 0.2 2.9 0.7 0.0 0.0 0.2 0.3 1.3 0.1 0.0 0.4 0.6 0.0 8.4 1.5 0.0 0.9 0.7 0.4 3.8 0.0 0.5 0.3 0.7 0.1 0.1 5.3 8.8 0.0 4.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 3.4 2.6 2.1 1.2 1.2 2.0 1.6 2.4 0.8 1.7 0.9 0.4 0.0 0.0 0.7 0.9 0.3 0.4 0.3 1.8 0.5 2.9 4.7 4.2 0.0 0.0 1.8 0.0 0.1 0.0 0.3 1.9 2.6 796.2 1.8 0.2 1.2 0.0 0.0 3.5 3.5 0.1 2.1 0.5 1.0 0.0 0.2 2.2 0.5 0.1 0.0 1.3 1.1 4.1 0.0 0.3 175.5 7.2 0.9 3.6 1.9 0.1 3.1 1.0 0.5 1.8 2.2 0.3 6.0 9.3 0.4 0.0 2.3 4.4 5.3 0.0 1.7 2.5 552.8 6.1 1.5 0.4 0.0 0.3 0.7 1.1 0.1 CCDC112 MGC39633 ENSG00000164221 "Coiled-coil domain containing 112" Q8NEF3 5 115267190-115296693 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 40.7" "Cell type enhanced" "Detected in many" "Spermatocytes: 201.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPMI-8226: 113.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045120, HPA050621" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 78: Testis - Spermatogenesis" "Cluster 25: RPMI-8226 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Plasma membrane, Cytosol" Nucleoplasm "HPA045120: AB_2679222, HPA050621: AB_2681191" "unprognostic (1.88e-2)" "unprognostic (5.10e-2)" "unprognostic (4.63e-2)" "unprognostic (5.60e-3)" "unprognostic (2.95e-1)" "unprognostic (1.21e-1)" "unprognostic (2.32e-6)" "unprognostic (4.30e-2)" "unprognostic (3.24e-1)" "unprognostic (4.41e-2)" "unprognostic (3.33e-1)" "unprognostic (2.64e-1)" "prognostic unfavorable (1.51e-6)" "unprognostic (7.00e-2)" "unprognostic (2.79e-2)" "unprognostic (8.61e-2)" "unprognostic (4.10e-3)" 4.3 3.6 5.7 5.3 6.3 7.3 6.0 7.4 7.3 4.5 2.6 9.1 7.2 5.6 6.2 4.5 4.1 3.1 6.0 5.8 6.6 2.8 1.2 5.5 4.6 6.4 5.5 2.1 10.2 4.5 4.6 2.4 6.3 6.7 9.3 7.9 6.5 5.0 4.3 4.9 6.3 5.4 5.7 4.6 6.4 40.7 5.9 3.7 4.0 2.5 4.2 3.8 3.6 7.8 12.0 5.9 11.5 18.5 7.1 14.0 2.9 10.5 5.3 7.7 8.7 2.6 6.7 14.8 8.9 7.2 11.4 7.5 12.1 6.0 16.0 12.0 10.1 9.8 8.8 3.8 9.7 12.9 4.8 6.4 7.2 9.8 13.0 8.8 12.1 13.1 4.1 11.6 10.8 9.3 19.2 11.4 13.1 11.0 11.0 20.6 14.5 113.7 7.7 4.2 17.9 23.5 11.5 7.2 32.8 7.8 12.2 18.9 12.6 10.1 6.9 19.7 14.8 13.2 13.2 3.0 6.7 9.9 6.0 0.3 5.0 11.0 2.9 4.0 3.3 2.8 2.2 2.5 5.4 4.0 2.8 1.9 3.2 3.0 4.9 10.2 0.1 2.1 5.7 6.3 7.4 7.3 5.8 6.6 6.4 5.5 6.3 5.7 5.9 7.8 15.7 16.0 14.0 16.0 19.2 14.1 5.0 6.0 8.0 29.2 19.4 18.4 17.6 8.6 8.4 5.5 10.4 0.7 19.5 23.6 5.9 28.2 8.5 23.0 21.4 12.4 40.6 20.8 26.4 25.9 2.0 11.5 14.3 12.3 9.5 15.0 7.9 3.1 32.7 10.1 15.2 33.4 6.1 28.6 31.5 18.5 4.1 31.5 14.2 15.0 36.6 11.0 11.3 21.1 54.7 27.1 18.7 4.1 27.3 8.0 11.8 4.4 11.7 24.9 13.1 18.5 18.2 201.8 73.3 13.8 22.6 0.5 9.2 5.5 32.8 3.4 CCDC138 FLJ32745 ENSG00000163006 "Coiled-coil domain containing 138" Q96M89 2 108786757-108885477 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 10.9" "Cell type enhanced" "Detected in many" "Early spermatids: 154.1;Excitatory neurons: 56.5;Inhibitory neurons: 58.9;Oligodendrocytes: 48.7;Respiratory ciliated cells: 43.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049899, HPA054223" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm Cytosol "HPA049899: AB_2680941, HPA054223: AB_2682420" "unprognostic (2.34e-1)" "unprognostic (3.74e-2)" "unprognostic (3.22e-2)" "unprognostic (3.04e-1)" "unprognostic (2.83e-2)" "unprognostic (1.64e-2)" "unprognostic (2.24e-5)" "unprognostic (2.89e-1)" "unprognostic (1.01e-4)" "unprognostic (2.56e-1)" "unprognostic (1.64e-1)" "unprognostic (5.77e-2)" "unprognostic (7.06e-4)" "unprognostic (7.88e-2)" "unprognostic (4.73e-2)" "unprognostic (2.69e-1)" "unprognostic (8.93e-2)" 1.0 0.9 2.0 2.0 1.8 3.5 2.4 4.8 3.1 1.3 2.1 1.9 1.0 2.1 1.3 2.1 4.3 1.8 0.7 2.4 2.3 1.7 2.8 1.3 4.5 2.6 2.4 1.6 1.7 0.7 0.8 1.3 2.4 1.4 2.3 2.3 1.3 0.7 1.0 2.4 1.7 1.5 2.0 1.2 1.8 10.9 2.0 6.4 0.8 0.7 3.8 1.6 1.3 3.0 14.7 6.7 22.4 11.6 1.8 2.0 14.2 6.3 2.0 14.6 10.6 21.8 8.4 35.2 9.2 2.0 7.3 12.2 16.3 8.5 13.0 8.2 21.0 16.3 11.6 18.2 2.2 22.4 2.3 1.4 2.5 17.2 5.1 2.2 7.7 15.0 31.4 15.8 7.5 8.2 32.2 15.3 33.3 8.0 6.9 21.1 21.2 21.3 8.1 11.5 15.7 15.3 13.6 7.3 11.1 13.6 7.8 10.7 4.9 9.2 16.2 6.0 13.5 4.9 12.2 36.4 3.8 17.2 9.3 2.6 0.5 0.8 1.1 1.2 2.2 3.0 1.5 2.3 0.5 3.2 2.2 2.6 0.3 2.0 0.4 4.8 2.4 1.2 2.0 1.8 4.8 3.1 2.4 2.3 2.6 2.4 2.4 2.0 2.0 3.0 2.4 0.0 3.3 14.7 7.9 2.4 3.5 4.5 6.8 7.3 3.6 3.9 1.4 2.8 9.6 1.8 8.4 5.2 13.6 0.9 1.9 3.7 154.1 38.9 7.0 2.7 5.4 5.9 56.5 1.4 5.5 6.3 8.6 7.3 4.5 6.7 1.1 2.4 2.2 6.7 58.9 2.5 2.0 1.6 1.5 34.0 3.7 3.9 1.8 10.3 1.3 1.8 6.2 19.1 48.7 3.3 0.5 1.9 14.4 1.1 0.7 1.7 43.8 7.0 0.0 5.0 3.5 29.5 20.1 7.0 2.8 1.4 5.9 5.5 2.9 2.3 CCDC142 FLJ14397 ENSG00000135637 "Coiled-coil domain containing 142" Q17RM4 2 74471986-74483408 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 28.3;Respiratory ciliated cells: 31.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA056946 Approved NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 45: Intestine - Brush border" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 11: Alveolar cells - Smell perception" "HPA056946: AB_2683282" "unprognostic (2.00e-1)" "unprognostic (3.25e-2)" "unprognostic (3.93e-2)" "prognostic unfavorable (1.87e-4)" "unprognostic (1.73e-1)" "unprognostic (1.69e-3)" "prognostic unfavorable (4.46e-4)" "unprognostic (9.05e-2)" "unprognostic (5.15e-2)" "unprognostic (2.44e-2)" "unprognostic (5.65e-3)" "unprognostic (8.94e-3)" "prognostic unfavorable (3.71e-7)" "unprognostic (1.31e-1)" "unprognostic (1.46e-1)" "unprognostic (3.27e-2)" "unprognostic (5.31e-3)" 1.9 2.6 3.0 2.4 2.9 1.5 1.9 5.6 3.5 2.7 3.6 2.8 4.4 2.6 1.3 2.4 2.4 1.2 1.8 2.8 2.6 2.2 4.6 1.8 2.6 3.5 2.7 2.6 2.2 2.7 2.9 1.2 3.1 2.8 1.9 1.3 2.4 2.0 1.5 2.6 3.3 1.5 2.3 3.3 2.4 3.2 3.1 2.5 2.4 1.2 2.2 2.3 2.0 4.1 2.7 2.1 4.3 3.4 2.8 2.7 7.5 4.0 2.4 3.2 2.4 6.3 3.8 3.2 2.6 2.5 3.9 4.8 2.8 3.1 2.1 4.5 8.9 5.6 7.7 4.6 1.2 3.6 4.2 1.9 2.1 5.0 2.1 4.1 2.5 3.8 2.6 2.2 3.0 2.3 4.8 3.6 4.1 4.7 5.3 5.7 7.8 2.9 1.9 3.9 5.5 3.4 3.1 6.4 3.5 3.1 4.3 2.5 2.1 6.3 4.0 4.4 4.9 6.6 3.1 3.2 2.9 1.9 3.7 6.3 3.0 5.9 5.1 1.8 4.1 3.3 2.9 3.6 1.6 5.3 4.6 3.8 2.4 4.7 3.8 2.9 1.4 1.1 3.0 2.9 5.6 3.5 2.8 2.6 3.5 2.7 3.1 2.3 3.1 4.1 2.5 9.6 28.3 3.3 6.1 3.2 2.4 1.4 1.8 16.4 2.8 2.0 4.1 2.8 16.2 0.0 18.8 3.1 6.1 6.2 1.9 2.7 1.1 1.3 4.2 5.6 6.0 4.8 3.3 2.0 2.2 6.7 4.1 1.8 18.3 8.6 6.8 2.1 2.0 5.0 3.6 5.3 0.0 3.3 3.0 0.4 7.5 5.8 0.0 5.6 4.2 11.5 16.5 2.5 2.4 1.5 5.7 6.0 4.6 1.7 14.0 1.3 31.2 22.9 0.0 6.1 4.0 8.1 5.0 1.2 3.0 1.9 7.7 5.9 6.3 2.0 CCDC158 FLJ25770 ENSG00000163749 "Coiled-coil domain containing 158" Q5M9N0 4 76312997-76421868 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "testis: 33.5" "Group enriched" "Detected in some" 7 "Early spermatids: 88.5;Late spermatids: 81.7;Spermatocytes: 66.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (3.31e-2)" "unprognostic (1.63e-1)" "unprognostic (7.49e-2)" "unprognostic (3.30e-2)" "unprognostic (3.29e-3)" "unprognostic (1.60e-1)" "unprognostic (2.60e-3)" "unprognostic (6.99e-2)" "unprognostic (1.57e-1)" "unprognostic (9.70e-2)" "unprognostic (1.08e-3)" "unprognostic (2.18e-1)" "unprognostic (9.77e-3)" "unprognostic (6.22e-2)" "unprognostic (3.65e-2)" "unprognostic (9.29e-2)" "unprognostic (2.68e-1)" 0.5 0.1 0.0 0.0 0.1 0.0 1.1 0.3 0.4 0.1 0.0 0.2 0.0 0.2 0.9 0.1 0.2 0.2 0.3 0.0 0.5 0.5 1.6 0.1 0.0 0.3 0.5 0.0 0.3 0.0 0.5 0.0 0.3 0.5 0.0 0.2 0.5 0.3 0.0 0.0 0.0 0.4 0.3 0.0 0.0 33.5 0.1 0.0 1.3 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.4 0.0 0.5 0.3 0.5 0.3 0.3 0.1 0.4 0.0 0.0 0.0 1.3 0.0 0.1 0.2 0.0 0.0 0.7 1.0 2.4 0.8 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 88.5 2.3 0.1 0.1 0.0 0.0 10.9 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.0 1.1 0.0 0.0 1.8 0.0 0.0 0.0 0.0 81.7 0.6 0.3 0.0 0.0 0.0 1.1 0.0 3.0 3.0 0.1 0.0 0.7 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.3 0.2 66.7 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 CCDC175 C14orf38 ENSG00000151838 "Coiled-coil domain containing 175" P0C221 14 59504539-59576812 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 18.4" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 8.4;Early spermatids: 11.9;Excitatory neurons: 15.9;Respiratory ciliated cells: 7.4;Rod photoreceptor cells: 11.4;Spermatocytes: 17.7" "Not detected" "Not detected" "Region enriched" "Detected in single" 22 "cerebellum: 18.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA004200 Uncertain Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm "Nucleoli, Cytosol" "HPA004200: AB_1078743" "unprognostic (3.64e-3)" "unprognostic (8.05e-2)" "unprognostic (1.13e-1)" "unprognostic (2.21e-1)" "unprognostic (3.83e-1)" "unprognostic (2.02e-2)" "unprognostic (5.98e-2)" "unprognostic (1.27e-1)" 0.0 0.0 0.1 0.0 0.2 0.1 0.0 18.4 0.5 0.0 3.3 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.7 0.8 0.0 0.0 0.0 0.4 0.0 0.8 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 2.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 18.4 0.5 0.0 0.2 0.7 0.8 0.8 0.4 0.1 0.2 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.6 0.0 8.4 0.0 0.0 1.1 0.0 0.0 11.9 5.0 0.1 0.0 0.0 1.7 15.9 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.3 0.0 0.0 1.5 4.8 0.0 0.3 0.0 0.0 0.1 1.5 0.0 5.0 3.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 7.4 11.4 0.0 0.4 0.3 17.7 4.4 0.0 0.0 0.0 0.0 0.1 2.4 0.1 CCDC184 "C12orf68, LOC387856" ENSG00000177875 "Coiled-coil domain containing 184" Q52MB2 12 48183644-48185926 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 25.7" "Cell type enhanced" "Detected in many" "Early spermatids: 62.5;Late spermatids: 15.1;Sertoli cells: 46.0" "Cancer enhanced" "Detected in many" "glioma: 6.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 2.7;AF22: 6.3;hTERT-RPE1: 2.4;SH-SY5Y: 4.3;U-2 OS: 2.5;U-87 MG: 3.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039947, HPA041715" Uncertain Approved Mitochondria,Cytosol No No "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 12: NES - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" "Mitochondria, Cytosol" "HPA039947: AB_2676764, HPA041715: AB_2677634" "unprognostic (2.02e-1)" "unprognostic (1.16e-2)" "unprognostic (6.97e-2)" "unprognostic (2.03e-1)" "unprognostic (1.61e-2)" "unprognostic (4.59e-1)" "unprognostic (1.33e-2)" "unprognostic (6.65e-2)" "unprognostic (9.79e-2)" "unprognostic (8.38e-2)" "unprognostic (1.03e-2)" "unprognostic (1.07e-1)" "unprognostic (5.87e-4)" "unprognostic (1.08e-2)" "unprognostic (2.39e-2)" "unprognostic (2.55e-1)" "unprognostic (2.36e-2)" 1.1 5.3 12.3 0.9 12.0 0.1 1.0 11.2 21.4 3.5 1.1 1.8 0.2 5.4 0.3 0.9 1.0 1.3 2.3 10.8 25.7 0.7 0.3 0.8 0.2 18.3 12.5 7.5 0.6 5.8 11.6 2.3 24.5 1.4 0.4 5.0 0.4 0.8 0.9 0.4 0.9 1.4 7.5 0.9 1.0 6.2 11.9 0.0 0.9 0.4 0.0 2.0 1.5 10.8 0.0 2.7 6.3 0.2 0.5 0.5 0.0 0.2 1.2 0.3 0.5 0.3 0.1 0.0 0.1 0.2 1.6 0.1 0.6 0.1 0.0 1.5 0.1 0.0 0.0 0.0 0.2 0.0 0.5 0.2 0.0 0.0 0.0 2.4 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 4.3 0.5 0.0 0.1 0.1 0.0 0.0 0.1 0.7 2.5 0.0 0.1 0.0 0.0 0.0 3.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.3 12.0 11.2 21.4 10.8 25.7 18.3 12.5 24.5 7.5 11.9 10.8 1.2 0.0 0.0 2.6 1.1 0.0 0.1 0.0 6.2 2.3 0.3 1.9 0.6 0.0 0.6 0.0 0.0 0.7 2.0 0.1 0.0 0.3 62.5 0.4 9.4 3.1 5.3 0.0 5.6 0.0 0.6 11.2 1.1 0.2 0.0 4.2 6.8 0.0 0.9 5.0 12.7 0.0 0.0 0.3 0.0 15.1 0.3 0.5 0.0 1.0 0.0 3.0 0.0 1.5 1.1 0.1 0.0 2.2 0.2 0.1 0.0 0.0 5.1 7.0 46.0 8.6 7.6 12.7 1.8 2.2 0.0 1.5 3.2 1.8 0.0 0.0 CCDC185 "C1orf65, FLJ35728" ENSG00000178395 "Coiled-coil domain containing 185" Q8N715 1 223393415-223395465 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 86 "testis: 35.4" "Cell type enriched" "Detected in some" 8 "Early spermatids: 518.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 29: Early spermatids - Spermatogenesis" "unprognostic (1.71e-1)" "unprognostic (1.55e-2)" "unprognostic (2.41e-6)" "unprognostic (9.69e-2)" "unprognostic (1.79e-2)" "unprognostic (1.12e-2)" "unprognostic (1.53e-1)" "unprognostic (4.65e-1)" "unprognostic (2.58e-1)" "unprognostic (1.37e-3)" "unprognostic (3.13e-1)" "unprognostic (2.61e-2)" 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 35.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 518.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 59.4 4.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 CCDC191 KIAA1407 ENSG00000163617 "Coiled-coil domain containing 191" Q8NCU4 3 113964137-114056594 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 37.5;Endometrial ciliated cells: 68.0;Respiratory ciliated cells: 104.2;Rod photoreceptor cells: 40.4;Spermatocytes: 68.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047833 Approved Approved Mitochondria NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" Mitochondria "HPA047833: AB_10961639" "unprognostic (2.59e-2)" "unprognostic (3.93e-2)" "unprognostic (1.86e-1)" "unprognostic (1.31e-2)" "unprognostic (2.60e-1)" "unprognostic (1.42e-2)" "unprognostic (6.57e-2)" "unprognostic (5.91e-2)" "unprognostic (1.08e-1)" "unprognostic (2.90e-1)" "unprognostic (6.33e-2)" "unprognostic (3.64e-2)" "unprognostic (2.53e-2)" "unprognostic (1.51e-1)" "unprognostic (3.62e-1)" "unprognostic (1.54e-1)" "prognostic favorable (3.45e-4)" 2.9 3.3 4.2 3.1 3.9 2.9 4.7 3.1 4.4 4.6 11.7 3.4 1.8 5.3 7.9 2.5 12.1 3.5 1.8 3.8 4.0 7.7 1.9 4.7 4.4 5.7 5.7 4.8 5.1 7.9 10.9 2.1 4.2 5.0 3.2 14.0 3.6 4.8 0.9 7.6 4.0 2.7 4.7 5.6 3.1 9.7 4.0 2.8 8.3 0.8 4.1 3.5 3.3 4.0 3.7 1.9 3.0 2.5 0.8 4.3 0.9 0.8 1.5 1.1 1.8 0.4 4.1 1.0 1.4 1.5 1.0 4.6 0.9 1.6 2.6 0.7 0.7 0.8 0.7 0.3 1.2 1.1 0.5 1.8 4.2 1.5 2.2 2.0 2.2 2.8 0.3 2.1 0.7 1.6 2.3 0.4 0.5 2.4 1.4 1.4 0.6 2.0 4.2 1.8 1.8 2.9 1.5 0.3 1.5 1.5 7.2 0.4 2.4 2.1 0.5 0.9 0.5 3.0 2.6 3.5 2.7 0.6 1.0 0.1 0.8 1.6 0.9 0.8 1.0 8.9 1.8 1.5 0.9 8.3 0.9 1.5 4.4 0.8 0.5 3.7 1.4 0.9 4.2 3.9 3.1 4.4 3.8 4.0 5.7 5.7 4.2 4.7 4.0 4.0 5.2 12.8 14.4 0.0 20.0 0.0 4.0 0.0 4.6 8.9 5.7 7.0 0.0 0.0 16.1 12.9 37.5 1.8 7.9 1.5 13.7 5.4 27.1 68.0 9.5 3.7 4.9 2.1 0.0 3.6 0.5 4.0 9.7 10.6 1.3 9.1 4.6 1.3 3.0 20.2 0.0 2.3 0.0 3.2 0.0 13.1 4.1 3.0 0.0 0.0 2.0 21.6 4.1 0.0 0.0 2.6 1.0 5.3 3.0 1.7 2.4 5.0 104.2 40.4 0.0 6.3 3.5 68.3 13.3 4.3 0.0 0.3 4.5 8.1 2.7 2.8 CCDC196 "C14orf53, LINC00238, NCRNA00238" ENSG00000196553 "Coiled-coil domain containing 196" A0A1B0GTZ2 14 66411704-66498677 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 11 "testis: 5.4" "Cell type enhanced" "Detected in some" "Exocrine glandular cells: 1.0;Proximal tubular cells: 2.0" "Cancer enhanced" "Detected in single" "breast cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 30: Mammary glandular cells - Lactation" "unprognostic (2.96e-2)" "unprognostic (6.53e-2)" "unprognostic (6.56e-2)" "unprognostic (2.57e-2)" "unprognostic (2.53e-1)" "unprognostic (4.47e-1)" "unprognostic (7.20e-2)" "unprognostic (9.22e-2)" "unprognostic (3.60e-6)" "unprognostic (5.72e-2)" "unprognostic (7.10e-2)" "unprognostic (6.03e-2)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.4 0.1 0.1 0.1 0.1 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CCDC197 "C14orf48, LINC00521" ENSG00000175699 "Coiled-coil domain containing 197" 14 93987225-94008863 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 7 "testis: 8.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-266/70: 1.3" "Not detected" "Not detected" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 29: U-266 - Adaptive immune response" "unprognostic (5.01e-1)" "unprognostic (1.09e-1)" 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 8.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.1 0.1 0.0 0.6 0.0 0.6 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CCDC34 "L15, NY-REN-41, RAMA3" ENSG00000109881 "Coiled-coil domain containing 34" Q96HJ3 11 27330827-27363234 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 48.8" "Cell type enhanced" "Detected in many" "Early spermatids: 383.4;Endometrial ciliated cells: 156.1;Spermatocytes: 336.8;Spermatogonia: 218.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "U-266/84: 159.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037574 Uncertain Approved "Nuclear membrane,Nucleoli fibrillar center" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear membrane, Nucleoli fibrillar center" "HPA037574: AB_10795136" "unprognostic (8.23e-3)" "unprognostic (1.09e-3)" "unprognostic (7.47e-2)" "unprognostic (1.65e-1)" "unprognostic (1.46e-2)" "unprognostic (6.40e-2)" "prognostic unfavorable (1.32e-7)" "unprognostic (9.09e-2)" "unprognostic (1.34e-3)" "prognostic favorable (8.52e-4)" "unprognostic (1.16e-1)" "unprognostic (4.06e-1)" "prognostic unfavorable (1.82e-4)" "unprognostic (4.97e-2)" "unprognostic (4.14e-2)" "unprognostic (1.64e-2)" "unprognostic (6.11e-2)" 3.8 5.3 16.1 5.6 15.9 13.7 11.2 13.8 32.8 4.4 16.7 8.8 10.7 4.9 11.3 5.5 12.5 3.4 3.4 15.9 15.4 5.0 4.6 2.3 6.5 15.2 14.9 9.7 4.3 8.1 5.5 5.1 15.4 5.4 10.1 6.2 4.1 4.3 3.1 6.5 8.9 3.5 14.3 4.4 9.3 48.8 15.9 15.8 5.6 3.4 8.8 3.3 3.5 14.8 46.1 50.4 41.6 44.7 7.5 17.6 30.8 29.5 11.1 29.8 28.8 28.2 8.3 49.4 20.2 15.8 42.7 40.2 41.9 18.2 54.3 19.5 58.2 39.4 62.6 74.1 3.8 40.6 15.4 5.7 13.4 26.0 12.5 13.2 23.3 70.1 39.0 15.9 32.1 32.6 79.3 63.1 42.9 31.4 44.1 74.8 152.8 7.4 12.8 15.2 32.2 42.2 44.0 19.5 20.8 23.4 52.8 21.4 11.1 47.8 45.2 91.3 69.4 153.2 159.4 34.8 44.5 2.0 42.7 0.0 0.2 0.4 3.1 1.0 3.7 3.4 3.9 4.2 1.0 4.0 4.5 2.8 0.0 3.7 3.8 2.3 6.7 1.1 16.1 15.9 13.8 32.8 15.9 15.4 15.2 14.9 15.4 14.3 15.9 14.8 5.1 0.0 1.7 4.9 10.1 22.8 22.9 33.2 13.1 10.3 71.4 73.3 9.2 27.1 20.6 23.9 12.5 45.5 3.4 41.0 19.6 14.1 383.4 156.1 12.5 11.1 21.6 91.3 11.5 12.3 25.1 17.2 31.1 15.3 7.0 30.9 10.0 16.0 22.0 3.3 7.5 40.5 18.3 8.9 8.4 82.4 21.5 5.7 14.2 0.0 4.7 26.6 7.2 1.0 1.2 5.5 12.1 20.7 13.9 10.3 6.2 17.6 101.5 20.6 6.6 11.6 18.3 336.8 218.8 33.2 20.6 16.1 9.1 10.3 71.2 15.5 CCDC38 FLJ40089 ENSG00000165972 "Coiled-coil domain containing 38" Q502W7 12 95867048-95942635 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 16.8" "Group enriched" "Detected in some" 31 "Early spermatids: 93.8;Late spermatids: 33.8;Spermatocytes: 60.7" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (1.76e-1)" "unprognostic (1.49e-1)" "unprognostic (7.54e-3)" "unprognostic (2.00e-2)" "unprognostic (3.62e-1)" "unprognostic (5.22e-2)" "unprognostic (1.61e-3)" "unprognostic (3.29e-1)" "unprognostic (5.11e-2)" "unprognostic (8.37e-2)" "unprognostic (1.17e-3)" "unprognostic (2.25e-2)" "unprognostic (2.32e-1)" "unprognostic (1.14e-1)" "unprognostic (1.59e-1)" "unprognostic (4.96e-5)" "unprognostic (1.08e-2)" 0.1 0.7 0.3 0.2 0.2 0.7 0.1 1.2 0.5 0.1 0.2 0.0 0.1 0.2 0.1 0.0 0.1 0.1 0.0 0.3 0.1 0.3 2.8 0.1 0.2 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.5 0.1 0.0 0.8 0.2 0.1 0.1 0.0 0.7 0.1 16.8 0.2 0.0 0.2 0.1 0.1 0.0 0.0 0.5 0.1 0.3 0.2 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.4 0.2 0.1 0.0 0.1 0.3 0.2 0.2 0.2 0.1 0.0 0.3 0.0 0.1 0.1 0.2 0.0 0.1 0.0 0.5 0.0 0.2 0.0 0.1 0.1 0.2 0.1 0.0 0.2 0.1 0.0 0.1 0.0 0.1 0.3 0.7 0.2 0.2 0.4 0.1 0.1 0.2 0.0 0.2 0.2 0.3 0.0 0.3 0.4 0.2 0.2 0.1 0.2 0.3 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.1 0.5 0.1 0.0 0.1 0.1 0.0 0.3 0.2 1.2 0.5 0.3 0.1 0.1 0.1 0.1 0.0 0.2 0.5 0.4 0.0 0.0 0.3 0.3 0.1 0.1 0.0 0.0 0.2 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 93.8 0.1 0.1 0.4 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 2.0 0.1 0.0 1.3 0.0 0.0 0.3 0.0 33.8 1.2 0.2 0.0 0.0 0.0 0.5 0.0 1.5 0.9 0.0 0.0 0.0 0.2 0.1 0.1 0.3 0.0 0.4 0.0 0.0 0.0 60.7 1.8 0.0 0.0 0.1 0.3 0.1 0.0 0.1 CCDC65 "CFAP250, CILD27, DRC2, FAP250, FLJ35732, NYD-SP28" ENSG00000139537 "Coiled-coil domain containing 65" Q8IXS2 12 48904110-48931840 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "fallopian tube: 26.6;testis: 37.3" "Cell type enhanced" "Detected in many" "Early spermatids: 151.1;Endometrial ciliated cells: 92.7;Respiratory ciliated cells: 155.7;Spermatocytes: 85.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 8 "gdT-cell: 8.7;MAIT T-cell: 9.1;memory CD4 T-cell: 7.5;memory CD8 T-cell: 7.3;naive CD4 T-cell: 4.6;naive CD8 T-cell: 6.2;T-reg: 4.8" "Lineage enriched" "Detected in single" 11 "T-cells: 9.1" "Cell line enhanced" "Detected in many" "HeLa: 4.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038520, HPA057573" Uncertain Approved "Vesicles,Centriolar satellite" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 20: HeLa - Mitochondria" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "Centriolar satellite" "HPA038520: AB_10672714, HPA057573: AB_2683473" "unprognostic (3.06e-2)" "unprognostic (1.17e-1)" "unprognostic (4.22e-2)" "unprognostic (4.20e-3)" "unprognostic (1.44e-2)" "unprognostic (3.43e-2)" "unprognostic (2.86e-2)" "unprognostic (5.79e-3)" "unprognostic (3.23e-1)" "unprognostic (9.02e-2)" "unprognostic (1.52e-2)" "unprognostic (6.03e-4)" "unprognostic (1.69e-3)" "unprognostic (2.04e-1)" "unprognostic (7.80e-2)" "unprognostic (1.34e-2)" "unprognostic (6.16e-2)" 0.4 0.4 1.5 0.7 2.3 1.4 0.4 0.0 2.8 1.4 3.4 0.4 0.3 1.1 2.8 0.3 26.6 1.2 0.3 3.2 0.3 1.8 0.3 2.9 1.0 1.4 2.3 0.8 0.8 1.4 2.1 0.1 1.3 0.4 0.0 7.1 0.3 0.4 0.4 1.5 0.5 0.1 0.5 1.1 0.4 37.3 1.5 0.2 2.5 0.0 0.3 0.2 0.3 0.3 0.6 2.5 1.1 2.2 0.0 0.0 1.1 0.6 0.0 0.3 1.0 3.1 1.4 0.9 0.8 0.0 0.3 0.7 0.0 0.0 0.4 1.4 1.1 1.4 4.4 1.1 0.1 1.1 1.2 0.0 0.0 0.6 0.0 1.7 0.0 0.7 0.6 0.3 0.0 1.5 0.3 1.5 2.5 0.9 0.6 0.8 0.5 1.0 2.0 1.6 0.6 1.0 0.7 0.9 0.8 1.7 2.3 1.0 1.0 0.8 0.8 0.9 0.5 1.1 1.2 0.8 0.9 0.9 0.2 0.0 0.0 0.0 8.7 0.0 9.1 0.2 7.5 7.3 0.0 0.5 4.6 6.2 0.1 0.8 0.0 0.0 4.8 2.9 1.5 2.3 0.0 2.8 3.2 0.3 1.4 2.3 1.3 0.5 1.5 0.3 0.9 0.0 1.1 2.0 0.6 0.9 0.2 6.2 0.0 1.2 0.4 0.5 0.5 0.0 13.8 0.0 12.5 0.1 6.5 0.0 7.9 1.0 151.1 92.7 3.0 0.6 0.0 2.7 7.2 0.6 0.1 0.8 0.5 4.2 0.0 0.5 0.0 0.5 0.0 0.0 4.0 0.0 12.2 0.0 0.8 22.7 1.5 0.3 1.8 1.0 0.2 2.2 33.0 2.0 0.8 0.3 0.0 2.2 1.0 0.2 0.0 3.4 155.7 11.5 0.0 0.5 3.6 85.9 4.8 0.0 0.1 0.1 7.3 0.5 0.0 0.1 CCDC70 "DKFZP434K1172, FLJ25853" ENSG00000123171 "Coiled-coil domain containing 70" Q6NSX1 13 51861969-51866232 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 233 "testis: 135.2" "Group enriched" "Detected in some" 122 "Early spermatids: 982.5;Late spermatids: 3017.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA079644 Enhanced "Secreted in male reproductive system" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 31: Spermatids - Spermatogenesis" "HPA079644: " "unprognostic (5.73e-3)" "unprognostic (1.88e-1)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 135.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.4 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 982.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3017.7 13.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.3 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CCDC77 MGC13183 ENSG00000120647 "Coiled-coil domain containing 77" Q9BR77 12 389273-442642 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 24.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038854 Approved Approved "Nuclear membrane" NA Yes "Cluster 27: Non-specific - Gene expression" "Cluster 23: Testis - Cell cycle regulation" "Cluster 5: NTERA-2 - Transcription" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear membrane" "HPA038854: AB_10673121" "unprognostic (3.25e-1)" "unprognostic (2.32e-1)" "unprognostic (1.56e-1)" "unprognostic (1.76e-3)" "unprognostic (7.26e-3)" "unprognostic (2.34e-1)" "prognostic unfavorable (8.11e-7)" "unprognostic (2.54e-2)" "unprognostic (3.41e-3)" "unprognostic (2.89e-1)" "unprognostic (3.82e-1)" "unprognostic (2.62e-1)" "unprognostic (4.11e-3)" "unprognostic (1.27e-2)" "unprognostic (1.08e-1)" "unprognostic (3.19e-2)" "unprognostic (4.41e-3)" 3.4 5.0 3.1 6.2 4.9 4.6 4.5 3.1 4.9 3.6 1.8 4.1 4.6 5.0 2.2 4.1 3.8 3.2 3.1 3.9 4.6 3.8 3.4 3.9 6.8 4.5 4.1 5.2 2.5 2.3 2.4 3.6 4.3 3.5 4.7 3.4 3.0 2.6 4.7 5.2 3.6 3.4 2.8 4.8 3.3 12.5 3.9 9.7 4.0 3.2 6.2 3.1 3.6 7.7 10.0 13.2 28.7 18.9 9.5 8.1 29.4 24.7 11.6 23.3 37.4 13.4 17.1 23.8 5.9 9.8 13.6 13.6 20.5 7.2 25.0 52.0 20.1 26.9 26.5 17.8 5.5 22.2 12.9 6.5 4.3 21.9 13.5 14.0 15.6 22.7 22.4 24.2 23.9 6.0 21.6 15.7 57.0 13.8 9.9 24.4 51.8 14.7 8.7 7.3 8.2 21.1 24.5 9.4 12.9 42.4 7.4 16.7 14.8 11.6 22.5 20.6 29.0 6.8 13.9 29.8 15.7 22.0 20.3 2.5 4.5 3.9 4.7 6.4 4.9 5.9 4.3 5.2 4.8 8.1 3.0 4.5 3.4 6.2 8.1 5.2 3.3 3.1 3.1 4.9 3.1 4.9 3.9 4.6 4.5 4.1 4.3 2.8 3.9 7.7 4.6 0.0 6.2 2.6 9.4 4.1 3.6 3.5 3.4 3.1 4.1 4.4 3.7 2.8 4.4 3.7 6.2 6.8 8.6 2.9 7.9 3.2 24.2 5.6 5.5 4.4 2.4 5.0 8.1 2.0 8.0 4.7 6.6 4.5 7.0 8.1 3.6 2.3 5.5 1.7 7.9 4.5 8.2 6.6 2.9 15.3 4.1 5.5 1.8 3.7 6.0 6.5 8.2 8.0 13.7 2.0 5.9 4.5 7.0 2.6 2.0 3.4 5.4 5.5 6.6 7.4 4.3 22.3 18.0 6.7 3.8 5.6 6.6 4.4 4.1 2.2 CCDC86 MGC2574 ENSG00000110104 "Coiled-coil domain containing 86" Q9H6F5 11 60842113-60851081 "Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 8 "parathyroid gland: 377.6" "Cell type enhanced" "Detected in many" "Spermatocytes: 74.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041117, HPA041540" Enhanced Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 28: Myeloid DCs - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 25: RPMI-8226 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoli, Nucleoli rim, Mitotic chromosome" Nucleoplasm "HPA041117: AB_10794984, HPA041540: AB_10794299" "unprognostic (2.93e-1)" "unprognostic (6.59e-2)" "unprognostic (2.38e-1)" "unprognostic (1.47e-3)" "unprognostic (3.64e-1)" "prognostic unfavorable (7.36e-5)" "prognostic unfavorable (1.71e-4)" "unprognostic (1.65e-3)" "unprognostic (9.52e-2)" "unprognostic (1.25e-2)" "unprognostic (6.12e-2)" "unprognostic (4.47e-1)" "unprognostic (3.76e-2)" "unprognostic (7.54e-3)" "unprognostic (2.90e-1)" "unprognostic (2.16e-1)" "unprognostic (6.25e-2)" 25.6 26.7 12.0 14.3 13.3 10.2 20.8 13.1 14.2 12.9 11.2 14.1 11.4 16.7 3.5 19.4 15.2 6.9 16.0 12.7 13.5 19.2 13.7 11.8 11.6 13.2 13.5 13.8 23.9 377.6 24.9 11.6 13.7 23.9 5.8 8.2 12.2 8.6 34.7 22.7 12.3 10.4 12.3 12.7 16.4 48.9 12.7 8.8 12.9 13.7 8.5 20.2 14.5 14.1 83.4 110.2 26.5 76.1 21.8 35.7 36.3 54.3 42.4 98.1 52.4 95.0 53.7 98.9 100.7 31.0 69.7 73.3 94.2 65.7 48.2 35.7 101.3 51.0 45.8 133.2 70.7 80.7 82.6 39.5 48.7 90.2 61.8 14.3 75.8 53.5 166.0 46.9 50.3 97.3 125.2 122.6 107.0 48.6 156.3 81.4 39.6 253.5 37.2 33.8 59.9 38.9 34.7 79.5 64.6 17.6 80.8 30.3 45.9 93.6 59.6 131.6 118.2 41.0 66.5 109.2 78.2 86.0 118.6 1.7 13.5 4.2 9.1 29.4 9.7 9.4 9.6 8.3 29.8 9.0 11.5 10.2 1.0 6.9 9.3 16.6 9.7 10.1 12.0 13.3 13.1 14.2 12.7 13.5 13.2 13.5 13.7 12.3 12.7 14.1 9.3 0.0 2.2 2.0 8.9 37.0 22.2 5.7 28.5 12.1 9.9 10.3 0.6 4.3 4.0 1.8 8.4 17.2 5.7 5.3 7.9 18.6 25.6 6.8 9.4 12.7 7.2 8.8 2.0 12.2 20.4 10.2 9.7 7.7 5.1 7.9 3.6 3.1 18.4 3.3 1.7 5.7 6.1 2.5 16.5 15.0 11.5 7.3 16.0 1.0 5.3 3.9 4.1 1.0 1.3 19.2 3.6 6.0 8.6 24.0 4.4 7.3 1.3 8.3 19.7 10.7 19.1 74.6 18.8 21.2 31.0 8.2 7.0 12.5 11.3 18.8 CCDC88C "DAPLE, HkRP2, KIAA1509, SCA40" ENSG00000015133 "Coiled-coil domain containing 88C" Q9P219 14 91271323-91417844 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Wnt signaling pathway" "Guanine-nucleotide releasing factor" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 33.9" "Cell type enhanced" "Detected in many" "dendritic cells: 80.1;NK-cells: 142.2;Plasma cells: 93.2;Respiratory ciliated cells: 112.5;T-cells: 89.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "JURKAT: 55.6;Karpas-707: 50.1;SCLC-21H: 53.6;U-266/70: 58.5;U-266/84: 76.2" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 5 "basal ganglia: 37.0" HPA005832 Approved Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 16: U-266 - Nucleosome" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Nucleoli fibrillar center" "HPA005832: AB_1079202" "unprognostic (7.28e-2)" "unprognostic (2.33e-3)" "unprognostic (7.23e-2)" "unprognostic (5.06e-2)" "unprognostic (1.00e-1)" "prognostic favorable (3.47e-4)" "unprognostic (3.07e-2)" "prognostic favorable (2.90e-4)" "unprognostic (1.48e-1)" "unprognostic (2.13e-1)" "unprognostic (4.77e-2)" "unprognostic (1.03e-1)" "prognostic unfavorable (2.80e-4)" "unprognostic (7.48e-2)" "unprognostic (2.22e-1)" "unprognostic (2.15e-2)" "unprognostic (4.35e-2)" 4.5 1.4 5.9 19.4 23.9 31.2 6.9 3.2 7.1 4.0 2.5 9.4 13.3 3.1 1.6 12.5 12.2 6.2 4.0 3.6 3.9 6.8 3.6 9.7 33.9 5.6 6.7 1.0 8.3 5.3 5.2 2.4 4.6 9.4 7.0 1.0 10.1 3.9 2.3 7.0 11.7 2.3 4.3 21.7 12.4 8.0 7.8 20.4 2.5 2.7 20.4 8.1 7.6 3.2 8.5 6.9 7.5 9.5 0.0 0.0 34.9 0.0 0.0 0.0 0.0 6.8 13.4 45.1 6.1 0.0 0.4 0.4 11.3 6.4 0.0 28.8 4.7 10.0 4.8 9.9 0.7 23.0 8.4 0.0 11.4 0.0 0.0 0.7 8.6 55.6 11.2 50.1 0.1 24.9 24.2 29.6 7.1 6.2 11.5 19.5 0.2 14.2 2.6 10.2 53.6 11.6 4.6 16.9 4.6 5.6 10.2 20.7 2.6 0.0 0.2 0.1 0.1 58.5 76.2 22.8 0.0 20.1 0.1 7.8 3.3 1.3 9.4 1.9 8.8 2.5 6.0 9.2 1.8 2.1 3.8 5.8 2.3 4.0 3.0 2.0 10.7 4.1 5.9 23.9 3.2 7.1 3.6 3.9 5.6 6.7 4.6 4.3 7.8 3.2 26.6 3.2 28.8 7.8 54.1 9.3 15.9 19.0 27.9 0.0 15.3 7.6 19.8 10.0 22.1 14.7 0.0 3.6 80.1 29.6 0.0 4.4 9.6 62.6 1.4 17.3 23.9 20.6 7.1 5.9 2.2 4.2 20.4 12.1 2.5 1.3 20.3 1.6 6.3 0.0 2.5 15.3 22.4 21.0 12.4 18.7 4.1 18.9 1.8 9.4 20.1 8.0 142.2 8.0 5.2 7.8 18.2 3.0 93.2 16.8 13.1 13.2 112.5 0.1 0.0 2.9 4.4 4.7 17.4 31.2 9.5 1.8 89.2 3.3 19.4 19.8 CCDC9B "C15orf52, FLJ43339" ENSG00000188549 "Coiled-coil domain containing 9B" Q6ZUT6 15 40331452-40340967 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 12.8;Alveolar cells type 2: 10.0;Collecting duct cells: 20.2;Ductal cells: 30.0;Pancreatic endocrine cells: 18.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "basophil: 4.3" "Lineage enriched" "Detected in single" 10 "granulocytes: 4.3" "Cell line enhanced" "Detected in many" "HaCaT: 122.5;hTERT-RPE1: 110.8;WM-115: 138.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040484, HPA041834" Approved Approved Nucleoplasm,Cytosol NA NA 77000 "Cluster 38: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 17: WM-115 - Nervous system development" "Cluster 1: Pancreatic cells - Digestion" "Nucleoplasm, Cytosol" "HPA040484: AB_10794742, HPA041834: AB_10795643" "unprognostic (5.57e-3)" "unprognostic (1.85e-1)" "unprognostic (2.60e-3)" "unprognostic (2.33e-2)" "unprognostic (1.48e-2)" "unprognostic (2.68e-1)" "unprognostic (1.86e-2)" "unprognostic (1.01e-1)" "unprognostic (1.50e-1)" "unprognostic (7.06e-3)" "unprognostic (1.51e-2)" "unprognostic (2.50e-1)" "unprognostic (1.04e-3)" "unprognostic (1.55e-1)" "unprognostic (3.48e-1)" "unprognostic (1.50e-2)" "unprognostic (9.68e-2)" 4.9 10.3 9.5 7.7 13.1 2.8 8.1 10.9 10.7 12.0 15.0 73.4 9.9 23.9 7.3 33.2 10.8 12.0 53.0 9.0 12.7 10.2 5.0 12.3 3.3 13.1 12.6 4.0 25.3 11.3 10.2 3.9 12.7 16.2 12.5 4.3 28.3 22.7 67.4 15.4 18.1 24.2 11.6 5.6 22.3 8.3 12.7 1.3 45.2 65.1 5.9 25.9 16.7 12.6 50.0 6.8 0.0 0.4 1.1 4.6 2.5 14.8 14.6 16.1 15.6 0.5 44.7 0.3 20.1 47.8 58.6 122.5 0.2 40.4 15.1 0.0 0.3 14.9 64.4 4.7 8.5 0.2 2.8 5.7 9.0 6.9 20.3 110.8 11.6 0.8 0.1 0.7 27.9 0.0 0.5 0.0 0.2 23.1 12.7 0.0 4.2 0.2 48.0 2.8 0.1 3.6 8.8 19.1 8.4 0.2 1.9 2.3 62.1 29.7 47.2 7.9 39.8 0.0 0.1 0.6 36.2 2.8 138.3 4.3 0.2 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.5 0.4 0.1 0.2 0.0 0.2 9.5 13.1 10.9 10.7 9.0 12.7 13.1 12.6 12.7 11.6 12.7 12.6 2.7 12.8 10.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 5.5 3.0 0.0 0.0 1.3 20.2 0.0 0.0 0.2 0.0 1.9 30.0 0.0 1.8 0.4 0.6 0.0 0.0 0.0 3.7 0.1 0.6 0.0 2.0 0.0 0.1 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.9 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 CCL1 "I-309, P500, SCYA1, SISe, TCA3" ENSG00000108702 "C-C motif chemokine ligand 1" P22362 17 34360328-34363233 "Predicted secreted proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 2.2;lymphoid tissue: 1.2" "Cell type enhanced" "Detected in some" "Early spermatids: 2.2;granulocytes: 8.9;Late spermatids: 1.6;T-cells: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 38 "HMC-1: 702.6" HPA049861 Uncertain "Secreted to blood" NA NA 84400 "Cluster 25: Monocytes - Inflammatory response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 48: Smooth muscle cells - ECM organization" "HPA049861: AB_2680919" "unprognostic (6.52e-2)" "unprognostic (4.81e-3)" "unprognostic (5.84e-2)" "unprognostic (5.01e-1)" "unprognostic (6.04e-1)" "unprognostic (2.71e-1)" "unprognostic (1.37e-1)" 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.4 0.0 1.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 702.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.2 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 18.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.6 0.0 0.4 0.8 0.5 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.4 0.0 0.0 0.0 CCL24 "Ckb-6, eotaxin-2, MPIF-2, MPIF2, SCYA24" ENSG00000106178 "C-C motif chemokine ligand 24" O00175 7 75810825-75823356 "Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 71.4;lymphoid tissue: 71.8" "Cell type enhanced" "Detected in single" "Macrophages: 1.1" "Group enriched" "Detected in many" 5 "colorectal cancer: 67.6;pancreatic cancer: 17.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 4.6;OE19: 2.3;U-2 OS: 4.8" "Low region specificity" "Detected in single" "Region enriched" "Detected in many" 4 "spinal cord: 9.9" "Secreted to blood" NA NA 276000 "Cluster 11: Basophils - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "unprognostic (4.55e-2)" "unprognostic (1.13e-1)" "prognostic favorable (5.41e-4)" "unprognostic (1.26e-2)" "unprognostic (1.44e-2)" "unprognostic (5.56e-2)" "unprognostic (1.73e-1)" "unprognostic (1.93e-1)" "unprognostic (4.32e-2)" "unprognostic (1.71e-1)" "unprognostic (2.35e-1)" "unprognostic (3.15e-1)" "unprognostic (2.84e-1)" "unprognostic (2.31e-2)" "unprognostic (1.50e-1)" "unprognostic (1.18e-1)" "unprognostic (3.73e-2)" 2.8 0.4 0.4 16.0 0.3 0.8 1.0 1.1 0.6 0.7 0.4 27.4 23.0 0.5 1.2 2.4 0.3 2.0 0.7 0.5 0.2 0.5 5.0 14.2 14.0 0.4 0.3 0.4 0.4 0.5 0.1 0.2 0.4 0.4 71.4 0.5 0.8 0.6 0.5 0.9 63.5 2.3 0.2 71.8 3.5 1.3 0.5 1.6 0.5 0.7 3.2 12.2 0.6 1.2 0.1 0.4 0.3 0.3 0.2 0.6 0.3 0.0 0.1 0.1 0.0 0.1 4.6 0.4 1.4 0.0 0.2 0.3 0.2 0.1 0.2 0.1 0.4 0.1 0.4 0.1 0.0 0.1 1.3 0.9 0.3 0.1 0.1 0.2 0.1 0.2 0.4 0.4 0.0 0.0 0.2 0.6 0.1 2.3 0.2 0.3 1.6 0.2 0.1 0.3 0.3 0.2 0.1 0.2 0.0 0.2 0.4 1.2 0.1 0.4 4.8 0.4 0.4 0.3 0.1 0.1 0.5 0.2 0.1 0.7 0.2 0.1 0.1 0.7 0.1 0.1 0.1 0.0 0.1 0.3 0.1 0.1 0.5 0.3 0.0 0.2 0.1 0.0 0.4 0.3 1.1 0.6 0.5 0.2 0.4 0.3 0.4 0.2 0.5 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 CCL4 "Act-2, AT744.1, LAG1, MIP-1-beta, SCYA4" ENSG00000275302 "C-C motif chemokine ligand 4" P13236 17 36103827-36105621 "Cancer-related genes, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 192.9" "Cell type enhanced" "Detected in many" "dendritic cells: 3753.7;Hofbauer cells: 849.7;Macrophages: 1168.2;NK-cells: 1232.8;Plasma cells: 974.5;T-cells: 1948.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 414.7" "Group enriched" "Detected in all" 6 "granulocytes: 135.0;T-cells: 414.7" "Group enriched" "Detected in some" 6 "U-266/70: 51.6;U-266/84: 13.3" CAB007805 Approved "Secreted to blood" NA NA 144000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB007805: AB_598177" "unprognostic (6.03e-2)" "unprognostic (2.48e-2)" "prognostic favorable (3.54e-4)" "prognostic favorable (1.97e-5)" "unprognostic (2.06e-1)" "unprognostic (7.02e-2)" "unprognostic (9.08e-2)" "unprognostic (2.69e-1)" "prognostic favorable (3.97e-4)" "unprognostic (3.45e-1)" "unprognostic (8.57e-2)" "unprognostic (1.61e-1)" "prognostic unfavorable (1.68e-4)" "unprognostic (3.71e-1)" "unprognostic (1.30e-1)" "unprognostic (1.18e-1)" "unprognostic (1.18e-2)" 38.9 28.0 2.0 32.0 2.0 192.9 10.5 3.4 5.5 16.0 4.1 9.9 7.6 10.3 6.4 15.0 8.2 45.1 4.4 2.0 1.9 6.8 84.2 33.9 34.3 3.2 2.9 5.0 15.6 12.0 2.5 17.8 2.8 7.6 11.1 0.1 5.1 3.4 1.0 0.9 11.4 18.0 2.5 65.3 10.3 2.7 2.1 24.1 5.9 4.5 15.4 56.4 4.4 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.7 0.1 0.0 0.0 51.6 13.3 0.2 0.2 0.1 0.0 14.4 3.4 135.0 414.7 4.8 101.6 8.4 46.0 240.6 2.3 17.7 13.8 181.7 55.8 42.8 11.1 2.6 0.5 138.9 2.0 2.0 3.4 5.5 2.0 1.9 3.2 2.9 2.8 2.5 2.1 3.3 52.3 0.0 54.5 0.0 135.9 15.6 1.9 0.3 24.5 1.5 26.3 49.3 11.2 14.3 7.2 0.0 0.0 9.7 3753.7 1.2 0.0 0.4 20.8 3.7 4.7 77.6 1.2 60.9 0.0 0.4 11.3 18.9 118.3 5.5 60.8 0.2 21.4 10.5 849.7 1.7 0.0 1.5 0.0 429.4 428.0 32.6 0.9 1168.2 51.6 3.7 10.5 1.1 1232.8 0.0 0.0 0.2 0.1 0.4 974.5 0.8 0.4 2.8 5.8 5.2 0.0 3.9 20.9 0.4 0.4 11.0 14.5 25.9 1948.3 0.0 0.9 1.6 CCNA1 CT146 ENSG00000133101 "Cyclin A1" P78396 13 36431520-36442870 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 22.2;testis: 81.3" "Group enriched" "Detected in some" 5 "Early spermatids: 162.4;Endometrial ciliated cells: 119.1;Late spermatids: 91.1;Spermatocytes: 285.7" "Group enriched" "Detected in many" 4 "endometrial cancer: 20.7;head and neck cancer: 6.2;ovarian cancer: 18.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 103 "basophil: 49.2" "Lineage enriched" "Detected in single" 301 "granulocytes: 49.2" "Cell line enhanced" "Detected in many" "HMC-1: 350.9;NB-4: 71.4;THP-1: 71.5;U-937: 90.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA060646, HPA077614" Enhanced Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Nuclear bodies" "HPA060646: AB_2684336, HPA077614: " "unprognostic (1.92e-3)" "unprognostic (1.21e-1)" "unprognostic (4.69e-3)" "unprognostic (1.89e-3)" "unprognostic (5.46e-2)" "prognostic unfavorable (1.70e-4)" "unprognostic (1.51e-1)" "unprognostic (3.40e-1)" "unprognostic (1.24e-1)" "unprognostic (4.01e-3)" "unprognostic (1.64e-1)" "unprognostic (4.04e-6)" "unprognostic (7.04e-3)" "unprognostic (2.45e-1)" "unprognostic (1.42e-1)" "unprognostic (2.63e-2)" 0.4 0.9 5.9 0.4 5.9 2.1 0.7 2.3 7.8 5.8 4.1 0.6 0.4 3.7 7.0 0.4 18.0 0.7 0.3 5.5 7.3 0.5 0.1 1.4 0.3 5.3 5.4 0.5 0.1 22.2 8.2 0.0 10.7 0.5 0.1 1.0 0.6 0.1 1.2 0.3 0.3 8.2 4.9 0.6 0.4 81.3 6.1 0.4 0.6 0.4 0.6 0.6 1.1 4.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 15.2 0.1 15.5 1.2 12.9 1.4 0.1 0.0 0.7 0.0 0.4 0.0 0.6 8.0 350.9 0.3 34.1 0.7 2.8 5.5 0.9 1.7 0.0 0.5 0.2 4.4 0.4 71.4 2.5 0.0 8.8 0.0 8.3 0.0 2.3 0.0 2.5 5.8 0.0 8.4 0.2 1.8 0.0 71.5 4.5 0.0 0.0 0.1 2.9 0.8 0.0 0.0 0.3 90.3 0.6 49.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 5.9 5.9 2.3 7.8 5.5 7.3 5.3 5.4 10.7 4.9 6.1 4.0 0.1 0.0 0.6 0.3 0.3 0.6 0.6 19.1 0.0 0.4 0.5 1.4 0.4 0.0 10.3 0.0 0.0 0.1 0.0 0.1 0.0 0.2 162.4 119.1 1.8 0.4 0.0 0.0 3.5 0.0 0.8 1.1 0.0 31.9 5.1 2.2 0.0 0.0 0.2 0.0 3.0 0.0 6.1 0.0 1.8 91.1 3.1 1.1 0.0 0.0 0.0 1.4 0.0 0.5 0.4 0.0 0.0 2.6 0.0 0.7 0.0 0.1 29.3 0.8 6.6 0.5 1.5 285.7 2.4 0.0 0.4 0.3 0.9 0.0 0.1 1.1 CCNA2 "CCN1, CCNA" ENSG00000145386 "Cyclin A2" P20248 4 121816444-121823883 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Host-virus interaction, Mitosis" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 38.6;lymphoid tissue: 46.9;retina: 31.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 47.9;Erythroid cells: 102.1;Extravillous trophoblasts: 92.8;Plasma cells: 35.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 3.1" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basal ganglia: 3.4;white matter: 7.6" "CAB000114, HPA020626" Enhanced Enhanced Nucleoplasm,Cytosol Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cytosol" "CAB000114: AB_563675, HPA020626: AB_1847376" "unprognostic (4.02e-2)" "unprognostic (1.93e-1)" "unprognostic (7.66e-3)" "prognostic unfavorable (8.78e-4)" "unprognostic (1.25e-1)" "unprognostic (1.67e-2)" "prognostic unfavorable (9.17e-5)" "prognostic unfavorable (4.27e-4)" "unprognostic (3.92e-3)" "unprognostic (2.65e-2)" "prognostic unfavorable (4.43e-6)" "unprognostic (8.38e-3)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.65e-1)" "unprognostic (1.82e-1)" "unprognostic (6.07e-2)" "unprognostic (1.59e-1)" 1.5 1.2 2.5 11.4 2.5 38.6 2.5 3.5 4.7 4.3 2.5 9.8 10.1 2.5 0.6 8.4 2.2 1.8 1.3 2.3 2.4 1.5 1.6 1.8 25.0 2.8 2.7 3.8 0.8 0.6 2.7 10.5 2.6 1.9 11.5 31.7 1.8 0.8 0.7 6.7 9.9 4.0 2.6 4.6 4.4 6.2 2.6 46.9 1.2 0.5 24.4 2.9 3.9 3.5 177.1 45.3 120.5 51.8 6.4 16.3 98.8 119.7 52.8 156.7 115.6 99.4 106.5 161.2 31.7 63.8 55.0 58.0 154.2 71.1 128.0 77.8 70.8 129.7 56.0 96.9 1.5 197.0 88.0 4.2 5.3 65.1 38.7 24.7 95.4 84.3 187.9 156.9 126.1 63.8 251.8 113.1 95.5 109.9 49.8 114.1 233.5 78.2 44.8 34.6 51.0 53.8 63.1 76.0 32.4 89.8 63.7 81.9 56.5 72.7 109.3 77.4 115.9 98.0 112.3 181.9 41.5 197.6 82.4 0.0 0.1 0.3 0.1 0.0 0.0 0.1 0.9 0.6 0.4 0.0 0.0 0.2 0.1 0.8 0.1 0.0 3.1 0.9 2.5 2.5 3.5 4.7 2.3 2.4 2.8 2.7 2.6 2.6 2.6 3.5 0.8 0.0 1.1 1.6 5.7 2.8 1.5 5.5 1.8 2.9 1.9 1.8 0.8 0.0 1.6 0.0 12.5 47.9 1.9 4.9 0.0 0.7 9.6 0.6 2.7 3.3 1.2 102.1 3.3 0.2 92.8 6.3 9.2 2.1 0.0 18.1 4.2 0.9 25.3 0.0 4.1 7.7 8.2 6.9 3.6 2.1 0.9 3.6 1.8 2.8 0.2 1.2 0.0 4.5 5.2 0.5 3.1 1.2 35.5 3.3 1.8 0.2 2.5 14.2 0.0 0.9 6.0 10.3 17.7 24.0 1.3 8.5 6.3 1.4 19.9 2.1 CCNB2 HsT17299 ENSG00000157456 "Cyclin B2" O95067 15 59105126-59125045 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 74.6;lymphoid tissue: 73.1;testis: 69.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 67.9;Early spermatids: 228.5;Erythroid cells: 123.6;Extravillous trophoblasts: 128.3;Spermatocytes: 288.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 5 "T-reg: 22.7" "Lineage enriched" "Detected in many" 6 "T-cells: 22.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA008873, CAB009575" Enhanced Enhanced "Golgi apparatus,Cytosol" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "Golgi apparatus" "CAB009575: AB_2072392, HPA008873: AB_1078604" "unprognostic (2.69e-2)" "unprognostic (2.25e-1)" "unprognostic (4.43e-2)" "unprognostic (1.96e-2)" "unprognostic (1.77e-1)" "unprognostic (4.65e-2)" "prognostic unfavorable (2.83e-4)" "prognostic unfavorable (4.63e-4)" "prognostic unfavorable (3.21e-5)" "unprognostic (1.09e-1)" "prognostic unfavorable (1.74e-5)" "unprognostic (4.48e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.96e-1)" "unprognostic (1.41e-1)" "unprognostic (3.98e-2)" "unprognostic (4.44e-1)" 1.0 1.1 0.4 12.2 1.1 74.6 2.9 0.7 0.7 2.9 1.1 14.3 14.1 2.6 0.3 16.1 1.1 1.9 0.7 0.6 0.7 1.1 1.4 2.2 33.0 1.3 1.0 0.8 0.7 0.2 0.3 11.4 1.0 1.6 16.8 0.3 2.8 0.4 0.7 9.4 12.0 6.4 0.7 7.1 5.6 69.4 1.1 73.1 1.0 0.4 43.7 3.6 5.6 2.2 132.5 112.1 188.6 47.1 8.5 16.6 97.5 104.8 69.9 165.2 135.6 187.8 81.1 122.1 75.4 71.8 97.2 160.1 181.4 92.6 157.8 124.1 92.4 153.1 127.3 108.1 2.5 118.1 98.6 6.3 12.6 71.4 91.9 32.7 114.1 147.0 163.1 194.5 128.2 96.5 137.9 177.2 138.6 58.5 65.2 157.5 260.0 124.4 53.3 91.9 115.2 75.9 148.9 80.2 97.3 147.9 139.4 120.4 58.5 81.6 134.4 90.5 210.5 84.2 133.2 213.8 53.6 267.1 117.9 0.0 0.1 0.7 0.1 0.0 0.3 2.1 4.6 5.0 3.0 1.7 0.0 0.1 0.8 3.6 0.1 0.1 22.7 2.1 0.4 1.1 0.7 0.7 0.6 0.7 1.3 1.0 1.0 0.7 1.1 2.2 0.3 0.0 0.6 0.0 6.8 4.8 2.8 11.5 1.8 0.2 2.5 3.3 0.5 0.0 3.2 0.0 0.0 67.9 1.6 4.1 0.0 0.7 228.5 5.3 3.1 3.9 3.0 123.6 0.7 0.2 128.3 7.2 7.1 5.9 0.0 29.9 6.1 1.1 29.9 0.0 0.8 10.1 20.3 10.6 3.3 53.5 4.4 7.9 0.0 0.0 2.4 0.2 1.0 0.0 1.4 0.4 1.9 1.9 18.7 2.3 2.1 0.0 1.8 0.3 0.0 1.0 5.7 288.7 32.1 20.3 6.1 16.3 4.4 4.1 23.4 5.0 CCNJL FLJ14166 ENSG00000135083 "Cyclin J like" Q8IV13 5 160249083-160345396 "Predicted intracellular proteins" Cyclin "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 18.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 22.4;Alveolar cells type 2: 23.4;Intestinal goblet cells: 28.5;Paneth cells: 26.8" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "cerebellum: 18.6" "Group enriched" "Detected in some" 17 "neutrophil: 12.7;NK-cell: 4.2" "Group enriched" "Detected in many" 85 "granulocytes: 12.7;NK-cells: 4.2" "Cell line enhanced" "Detected in many" "HBEC3-KT: 49.8;RT4: 28.0;WM-115: 38.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA049970 Approved Approved "Nuclear speckles" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 21: Non-specific - Transcription" "Cluster 17: WM-115 - Nervous system development" "Cluster 27: Mucus-secreting cells - Mucin production" "Nuclear speckles" "HPA049970: AB_2680974" "unprognostic (1.09e-2)" "unprognostic (2.36e-2)" "prognostic favorable (7.31e-4)" "unprognostic (1.50e-3)" "unprognostic (1.79e-1)" "unprognostic (4.31e-2)" "unprognostic (1.60e-4)" "unprognostic (1.26e-2)" "unprognostic (6.92e-2)" "unprognostic (3.09e-1)" "unprognostic (2.57e-1)" "unprognostic (1.75e-2)" "unprognostic (6.27e-3)" "unprognostic (6.63e-3)" "unprognostic (2.62e-1)" "prognostic favorable (7.10e-4)" "prognostic favorable (8.02e-4)" 0.9 3.8 1.2 1.6 1.2 1.4 1.3 18.6 3.1 2.6 1.3 7.8 1.3 0.7 0.6 1.0 1.3 0.7 5.7 4.7 1.2 4.0 0.7 7.8 0.4 1.8 2.0 5.4 0.2 0.1 3.8 0.9 2.1 1.4 5.8 1.5 4.8 1.3 0.2 0.5 3.3 0.8 1.4 7.5 7.2 12.2 2.2 2.6 4.2 2.6 1.1 3.4 1.5 1.3 3.9 20.8 16.4 0.2 0.0 0.0 0.0 0.0 0.3 1.9 0.8 7.9 16.8 0.0 13.2 0.2 13.9 5.9 2.3 49.8 1.3 0.0 0.3 6.0 7.3 6.8 0.2 0.0 0.2 0.0 4.2 2.7 11.9 9.9 12.7 5.8 0.1 0.0 5.3 2.7 0.0 12.1 11.5 0.0 7.8 3.4 4.6 1.7 12.6 28.0 4.7 10.5 2.9 3.7 17.1 6.2 9.9 1.1 14.9 2.6 13.8 0.0 9.8 0.0 0.0 0.0 0.0 0.0 38.3 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.7 4.2 0.0 0.0 0.0 0.2 1.2 1.2 18.6 3.1 4.7 1.2 1.8 2.0 2.1 1.4 2.2 1.3 0.6 22.4 23.4 9.4 0.0 0.3 1.8 3.8 0.0 0.7 1.0 2.3 4.8 0.0 6.8 3.7 0.0 0.0 4.5 4.4 5.9 2.7 1.0 0.5 1.4 2.6 2.4 0.0 0.7 0.2 0.0 1.2 1.1 1.4 1.3 11.5 2.2 0.2 0.1 0.0 9.3 28.5 8.2 0.3 0.3 3.6 2.1 2.1 5.4 2.8 0.6 8.3 14.4 1.5 0.7 1.7 26.8 2.6 0.5 1.3 4.3 0.2 1.5 0.1 0.0 0.7 1.9 0.5 10.0 0.4 0.4 0.0 2.2 11.2 4.6 2.4 CCNY "C10orf9, CBCP1, CFP1" ENSG00000108100 "Cyclin Y" Q8ND76 10 35247025-35572669 "Predicted intracellular proteins" "Cell cycle, Cell division, Wnt signaling pathway" Cyclin "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 5 "Late spermatids: 3651.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 26.4" "Group enriched" "Detected in all" 5 "dendritic cells: 7.8;granulocytes: 26.4;monocytes: 23.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036290 Approved NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 78: Testis - Spermatogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "HPA036290: AB_10600860" "unprognostic (1.25e-2)" "unprognostic (1.48e-1)" "unprognostic (4.30e-2)" "unprognostic (2.23e-3)" "unprognostic (1.30e-1)" "unprognostic (4.65e-1)" "prognostic unfavorable (6.75e-5)" "unprognostic (3.37e-2)" "unprognostic (6.15e-3)" "unprognostic (4.06e-2)" "unprognostic (2.94e-1)" "unprognostic (1.10e-1)" "unprognostic (2.74e-2)" "unprognostic (1.31e-1)" "unprognostic (3.77e-2)" "unprognostic (1.98e-1)" "unprognostic (1.80e-1)" 28.6 21.9 35.1 21.2 37.1 35.9 23.7 31.6 35.1 21.8 24.8 28.4 21.5 28.4 26.9 20.5 22.2 22.7 33.1 37.0 32.4 24.8 31.0 25.9 23.4 32.0 33.6 25.2 20.6 17.9 15.5 38.7 31.9 18.3 20.0 19.3 17.0 20.1 25.5 19.3 22.2 25.7 32.3 24.4 26.3 81.2 35.5 22.5 29.6 22.9 21.0 25.4 17.3 33.4 52.3 22.2 29.3 28.2 41.6 56.5 38.2 27.4 27.7 26.0 24.9 32.4 51.7 33.2 38.1 44.1 22.7 27.1 26.3 34.6 27.7 105.0 17.3 62.0 16.0 42.4 45.8 22.7 28.3 40.3 48.1 39.9 27.1 57.6 63.3 38.3 49.1 27.3 51.6 33.2 39.9 19.6 11.2 29.6 46.2 33.0 54.4 20.7 33.2 24.6 25.8 39.3 21.5 42.7 38.6 25.4 36.9 41.8 75.5 32.1 38.6 49.4 23.9 18.3 16.6 24.4 56.0 46.6 15.1 1.7 23.4 5.2 3.3 6.5 3.6 3.1 3.2 3.5 7.8 2.4 3.2 3.6 26.4 2.9 3.4 4.0 2.3 7.6 35.1 37.1 31.6 35.1 37.0 32.4 32.0 33.6 31.9 32.3 35.5 33.4 102.2 32.1 25.9 91.1 23.4 26.9 14.1 29.0 13.6 43.5 30.2 28.7 33.1 41.5 32.1 38.6 20.9 12.0 35.2 25.8 5.9 16.5 709.0 29.5 37.2 59.8 52.8 12.4 205.5 27.8 18.1 34.4 20.4 33.4 16.5 35.3 32.5 85.3 28.9 48.8 130.0 29.0 26.4 80.4 46.9 3651.5 41.3 56.6 16.0 192.0 89.3 62.4 24.7 167.9 445.2 27.9 19.2 38.7 11.7 27.7 31.5 23.1 28.5 39.6 6.6 56.0 26.5 33.8 40.2 17.1 29.5 9.4 26.2 43.2 28.6 20.9 CCP110 "CP110, KIAA0419" ENSG00000103540 "Centriolar coiled-coil protein 110" O43303 16 19523811-19553408 "Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 48.1" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 210.2;Respiratory ciliated cells: 118.8;Spermatocytes: 169.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039402 Approved Approved "Centriolar satellite" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 14: REH - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Centriolar satellite" "HPA039402: AB_10671041" "unprognostic (2.83e-1)" "unprognostic (2.41e-2)" "unprognostic (3.08e-2)" "unprognostic (2.97e-1)" "unprognostic (1.65e-1)" "unprognostic (2.82e-1)" "unprognostic (4.88e-2)" "unprognostic (9.68e-2)" "unprognostic (3.25e-2)" "unprognostic (2.68e-1)" "unprognostic (6.50e-2)" "unprognostic (1.92e-2)" "unprognostic (8.99e-3)" "unprognostic (2.74e-2)" "unprognostic (1.82e-1)" "unprognostic (3.01e-2)" "unprognostic (1.37e-1)" 5.6 5.9 23.6 6.6 41.3 15.7 9.2 22.7 34.5 7.3 11.4 5.5 3.9 9.2 7.3 6.6 13.3 5.9 4.7 22.6 25.1 4.5 3.6 8.6 8.2 27.4 30.2 10.5 4.0 11.5 11.8 4.9 25.2 7.3 5.6 13.8 5.2 6.9 5.0 5.9 4.9 7.9 18.6 6.4 6.4 35.8 30.7 16.5 7.1 5.8 7.7 6.2 5.2 48.1 22.4 10.2 24.7 24.1 12.1 10.7 12.7 23.4 13.5 20.4 22.9 8.3 11.7 32.8 14.5 11.6 15.5 15.4 25.6 7.4 34.2 15.1 11.6 16.4 14.5 14.3 6.0 42.6 20.2 5.3 10.0 23.0 14.0 12.6 15.9 33.1 17.5 16.0 24.1 17.3 43.8 16.5 19.0 10.7 7.6 55.1 46.1 11.5 9.3 9.3 48.5 24.5 25.4 11.9 7.6 16.4 21.9 25.6 9.5 23.7 15.6 16.0 19.5 17.6 17.7 23.5 15.2 18.0 14.1 14.5 2.8 5.2 3.8 2.7 2.4 2.5 3.4 3.7 3.0 3.2 3.8 2.2 5.5 1.7 4.3 2.0 2.9 2.0 23.6 41.3 22.7 34.5 22.6 25.1 27.4 30.2 25.2 18.6 30.7 48.1 9.3 32.1 34.6 19.9 12.7 13.5 9.2 10.8 14.8 18.1 16.4 11.2 14.7 8.6 27.6 23.9 33.3 11.4 19.4 6.9 5.9 9.2 5.1 75.1 19.5 10.7 1.2 46.3 30.6 4.7 7.0 15.7 10.2 13.5 30.3 12.5 12.1 7.5 7.0 30.3 30.9 9.9 6.1 18.2 12.8 9.0 21.1 10.7 10.6 13.1 11.6 14.5 12.3 21.1 210.2 9.0 6.0 16.6 12.7 9.2 8.0 5.3 118.8 66.0 19.7 22.5 12.5 169.2 38.6 13.3 14.6 24.5 14.4 9.5 6.1 6.9 CCR1 "CD191, CKR-1, CMKBR1, MIP1aR, SCYAR1" ENSG00000163823 "C-C motif chemokine receptor 1" P32246 3 46201711-46208313 "CD markers, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 42.5" "Group enriched" "Detected in many" 4 "Extravillous trophoblasts: 81.2;Hofbauer cells: 117.4;Kupffer cells: 171.9;Macrophages: 74.2;monocytes: 51.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Karpas-707: 330.3;RPMI-8226: 158.5;U-266/70: 57.7;U-266/84: 183.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" "unprognostic (3.95e-1)" "unprognostic (2.17e-1)" "unprognostic (1.20e-1)" "unprognostic (2.16e-1)" "unprognostic (1.05e-1)" "unprognostic (6.66e-2)" "unprognostic (1.16e-1)" "unprognostic (8.82e-2)" "unprognostic (4.91e-3)" "unprognostic (2.20e-3)" "unprognostic (1.09e-1)" "unprognostic (9.60e-2)" "prognostic unfavorable (1.01e-4)" "unprognostic (1.08e-1)" "unprognostic (5.52e-3)" "unprognostic (1.47e-1)" "unprognostic (2.38e-1)" 21.0 4.7 2.1 42.5 2.3 24.8 4.0 2.4 3.1 2.5 2.6 5.6 7.3 2.5 1.6 3.4 2.8 11.7 2.4 1.9 2.6 4.9 17.2 18.7 10.9 5.2 3.2 2.1 3.1 1.9 0.9 26.4 4.5 1.6 7.3 0.3 2.1 2.6 1.3 0.6 6.6 15.5 4.7 30.8 4.9 1.7 4.9 5.7 1.0 3.3 10.2 16.7 0.7 7.4 0.3 0.0 0.0 0.0 0.0 3.3 0.2 0.0 0.2 0.0 0.3 0.7 1.5 0.1 0.4 0.0 3.6 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.5 6.1 0.1 0.0 0.2 0.1 0.0 0.0 0.2 0.0 330.3 0.0 0.2 0.2 13.0 0.0 0.0 0.0 0.1 0.0 158.5 0.0 5.6 0.0 0.0 0.0 0.4 1.3 0.9 0.2 35.5 0.0 0.8 0.0 0.0 0.2 57.7 183.7 0.1 29.1 26.5 0.4 82.5 125.1 25.8 10.5 76.2 50.1 2.9 0.1 8.5 53.9 0.2 0.1 1.4 113.4 84.5 51.3 18.9 0.1 50.6 2.1 2.3 2.4 3.1 1.9 2.6 5.2 3.2 4.5 4.7 4.9 7.4 0.3 3.2 3.0 0.0 2.0 0.9 0.0 0.0 0.6 0.0 0.1 0.5 0.6 0.0 1.3 0.0 0.0 1.3 15.9 0.0 1.9 0.0 0.4 0.1 0.6 1.6 0.0 1.7 0.0 0.0 81.2 2.4 0.0 0.0 3.8 0.0 1.4 1.2 117.4 0.0 0.0 0.0 0.0 171.9 23.5 0.1 0.0 74.2 5.4 9.4 51.5 0.2 7.2 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 3.2 1.5 0.2 0.0 0.4 0.5 0.0 0.2 0.2 1.7 2.9 6.0 0.0 0.0 0.0 CCT3 "Cctg, TRIC5" ENSG00000163468 "Chaperonin containing TCP1 subunit 3" P49368 1 156308968-156367873 "Plasma proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006543 Approved Approved "Plasma membrane,Cytosol" NA NA 1300000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Plasma membrane, Cytosol" "HPA006543: AB_1078426" "unprognostic (2.14e-2)" "unprognostic (3.20e-3)" "unprognostic (1.66e-1)" "unprognostic (6.00e-3)" "unprognostic (8.39e-3)" "unprognostic (3.14e-3)" "prognostic unfavorable (3.87e-7)" "unprognostic (4.43e-3)" "unprognostic (2.78e-1)" "unprognostic (1.16e-1)" "unprognostic (5.44e-2)" "unprognostic (1.74e-1)" "prognostic unfavorable (6.34e-4)" "unprognostic (7.16e-2)" "unprognostic (5.76e-2)" "unprognostic (5.67e-2)" "unprognostic (1.10e-1)" 85.3 122.3 121.4 103.0 125.8 79.5 119.4 132.2 176.7 77.1 139.0 95.3 87.2 93.6 77.1 106.9 119.9 67.4 100.8 125.3 135.5 114.5 108.3 60.1 123.9 129.4 126.1 113.5 82.3 120.4 65.3 93.3 129.5 86.6 112.9 135.7 74.9 89.8 134.8 93.8 83.3 137.3 132.4 67.1 80.7 120.3 130.2 129.1 87.6 120.8 148.5 136.7 70.6 143.8 432.3 562.3 324.3 311.9 352.5 261.2 419.7 388.8 315.9 617.9 378.0 611.1 396.3 689.5 442.3 337.9 392.5 395.5 1045.2 519.9 519.1 384.3 660.6 437.6 438.6 579.2 261.9 547.7 357.2 333.7 312.4 556.6 514.7 303.3 531.6 425.3 795.2 250.1 375.5 603.5 688.2 372.1 656.4 859.5 702.1 587.3 314.5 771.1 496.9 349.9 434.9 448.1 347.0 635.0 388.7 531.0 560.2 707.3 366.1 249.0 373.0 263.3 717.1 457.5 808.2 975.7 288.1 349.1 408.1 75.1 107.1 49.0 129.0 137.0 171.2 142.1 144.3 138.8 171.7 156.8 177.0 156.7 14.9 145.8 146.8 120.8 164.3 222.3 121.4 125.8 132.2 176.7 125.3 135.5 129.4 126.1 129.5 132.4 130.2 143.8 82.8 54.5 62.5 18.3 104.8 144.9 241.1 247.4 119.5 124.5 133.2 118.5 121.1 98.7 132.3 90.1 106.3 226.7 100.5 71.7 113.5 208.6 111.9 118.4 137.4 122.4 125.3 134.0 29.7 183.2 217.8 113.9 70.8 86.6 73.0 180.1 74.6 88.4 162.6 74.0 34.6 93.8 193.3 83.0 96.5 226.7 83.6 78.1 112.1 22.5 153.6 158.1 105.0 37.2 41.9 199.1 78.8 88.0 95.8 169.0 115.9 212.3 137.6 244.3 118.3 110.3 145.4 410.0 232.4 123.1 159.8 184.6 112.1 347.9 149.8 157.9 CCT6B "Cctz2, TSA303" ENSG00000132141 "Chaperonin containing TCP1 subunit 6B" Q92526 17 34927859-34981078 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 23 "testis: 126.1" "Group enriched" "Detected in many" 27 "Early spermatids: 448.5;Late spermatids: 185.2;Spermatocytes: 490.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RPMI-8226: 12.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA042996, HPA045576, HPA049949" Uncertain Approved Cytosol NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 25: RPMI-8226 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "HPA042996: AB_2678261, HPA045576: AB_2679372, HPA049949: AB_2680968" "unprognostic (1.56e-1)" "unprognostic (1.72e-2)" "unprognostic (2.99e-3)" "unprognostic (6.11e-2)" "unprognostic (3.38e-1)" "unprognostic (1.15e-1)" "unprognostic (1.12e-3)" "unprognostic (3.61e-2)" "unprognostic (1.75e-1)" "unprognostic (1.44e-3)" "unprognostic (9.56e-3)" "unprognostic (3.61e-2)" "unprognostic (4.82e-7)" "unprognostic (1.24e-1)" "unprognostic (4.30e-1)" "unprognostic (4.23e-4)" "unprognostic (1.49e-1)" 2.9 3.3 1.9 0.8 2.3 3.8 5.5 2.0 2.7 2.2 1.6 1.7 1.4 1.9 5.5 1.8 2.7 0.9 1.7 1.7 2.0 4.0 5.0 1.2 1.4 2.2 2.1 2.4 2.6 2.5 2.7 0.6 2.3 2.7 1.1 2.3 3.3 2.6 5.1 2.7 1.4 1.6 2.3 1.6 2.0 126.1 2.0 1.6 2.9 3.8 1.7 1.9 1.5 2.7 0.7 1.0 2.6 1.1 3.3 2.0 0.9 1.3 5.3 2.2 3.1 0.7 2.1 5.0 0.5 2.4 1.6 1.0 0.1 0.7 0.7 0.5 1.9 0.7 0.3 0.6 4.5 2.4 0.7 2.7 1.3 0.2 2.6 0.4 0.6 0.8 0.5 5.0 2.4 1.9 0.5 5.2 1.4 0.4 0.6 2.4 1.2 12.2 1.4 0.8 3.0 1.5 2.4 0.9 4.1 0.6 1.9 2.4 0.5 1.0 0.1 1.2 0.6 4.4 1.0 4.7 1.1 1.5 1.3 0.0 1.1 0.9 0.6 1.1 0.6 0.9 0.7 0.4 2.6 0.8 1.0 1.0 0.0 1.6 1.1 0.6 0.3 0.6 1.9 2.3 2.0 2.7 1.7 2.0 2.2 2.1 2.3 2.3 2.0 2.7 2.4 0.0 3.1 4.6 2.6 2.4 2.8 3.2 6.2 1.5 8.7 7.0 4.2 4.3 3.9 1.8 0.0 1.8 4.0 0.9 3.9 3.4 448.5 8.8 3.7 2.1 0.0 0.8 3.9 8.0 0.5 3.5 1.5 3.6 2.5 4.6 0.7 3.1 1.5 0.0 3.7 2.3 6.1 2.2 4.0 185.2 10.8 2.9 5.4 4.7 1.6 8.7 4.1 7.1 10.7 2.7 1.6 4.1 3.9 2.1 0.7 6.9 8.8 2.5 0.0 3.7 3.0 490.2 13.5 3.1 2.6 0.8 2.7 6.9 1.8 3.6 CD28 ENSG00000178562 "CD28 molecule" P10747 2 203706475-203738912 "CD markers, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "lymphoid tissue: 30.8;placenta: 14.8" "Group enriched" "Detected in some" 5 "Hofbauer cells: 34.1;T-cells: 52.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 101.9" "Lineage enriched" "Detected in many" 7 "T-cells: 101.9" "Group enriched" "Detected in some" 14 "Karpas-707: 360.6;RPMI-8226: 173.2;U-266/70: 294.1;U-266/84: 283.7" "Region enhanced" "Detected in single" "olfactory bulb: 1.0" "Not detected" "Not detected" HPA070003 Enhanced NA NA "Cluster 13: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "HPA070003: AB_2686226" "unprognostic (5.54e-2)" "unprognostic (2.16e-4)" "unprognostic (1.90e-3)" "unprognostic (2.49e-3)" "unprognostic (3.44e-2)" "unprognostic (6.07e-5)" "unprognostic (9.09e-2)" "unprognostic (4.66e-2)" "unprognostic (3.40e-1)" "unprognostic (1.15e-1)" "unprognostic (2.65e-1)" "unprognostic (1.68e-1)" "unprognostic (5.78e-5)" "unprognostic (4.77e-2)" "unprognostic (2.93e-2)" "unprognostic (7.79e-2)" "unprognostic (8.96e-2)" 4.0 0.3 0.0 14.9 0.1 3.3 0.8 0.1 0.1 1.1 0.9 1.7 1.1 0.7 0.3 0.9 0.5 4.1 0.6 0.1 0.1 0.5 1.3 1.9 28.0 0.1 0.0 0.3 0.5 0.2 0.1 14.8 0.1 1.0 1.9 0.1 0.6 0.8 0.3 0.3 3.0 1.4 0.1 7.2 2.5 0.7 0.2 30.8 0.5 0.1 18.6 4.6 0.3 0.1 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.1 0.7 2.0 0.0 360.6 0.2 0.0 19.9 0.0 0.1 0.0 0.0 0.1 0.3 173.2 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.1 0.1 0.1 0.3 294.1 283.7 2.9 0.3 0.1 0.0 1.7 0.6 1.0 8.3 0.5 50.6 0.3 54.5 26.1 0.1 0.3 48.1 18.6 13.8 0.2 0.5 0.2 101.9 14.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.1 0.5 0.0 1.3 0.0 2.4 2.9 0.1 0.0 0.6 0.0 0.2 0.3 0.3 0.0 0.0 0.0 0.0 0.2 3.2 0.1 0.0 0.0 0.1 0.2 0.1 0.5 0.0 0.0 0.1 0.0 0.3 1.0 2.0 0.1 1.3 0.0 0.0 0.1 34.1 0.0 0.0 0.0 0.0 0.8 5.3 0.2 0.0 4.4 0.0 1.0 1.5 0.0 2.1 0.0 0.1 0.0 0.0 0.0 8.5 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.5 0.0 0.1 0.2 1.6 0.1 52.6 0.0 0.0 0.0 CD300A "CMRF-35-H9, CMRF35H, IGSF12, IRC1, IRC2, Irp60" ENSG00000167851 "CD300a molecule" Q9UGN4 17 74466399-74484794 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 95.2" "Cell type enhanced" "Detected in some" "dendritic cells: 103.5;granulocytes: 59.5;Hofbauer cells: 114.0;Kupffer cells: 97.6;Macrophages: 90.9;NK-cells: 225.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 5 "HMC-1: 104.4;NB-4: 45.9;RPMI-8226: 88.7" "HPA010971, HPA011645" Approved Approved "Vesicles,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Vesicles, Cytosol" "HPA010971: , HPA011645: AB_1846988" "unprognostic (1.99e-1)" "unprognostic (4.60e-2)" "unprognostic (3.88e-2)" "unprognostic (3.30e-2)" "unprognostic (2.73e-1)" "unprognostic (2.01e-1)" "unprognostic (1.04e-2)" "unprognostic (2.63e-1)" "unprognostic (1.11e-1)" "unprognostic (1.17e-2)" "unprognostic (7.87e-2)" "unprognostic (1.07e-1)" "prognostic unfavorable (1.91e-5)" "unprognostic (5.97e-2)" "unprognostic (5.45e-3)" "unprognostic (1.36e-1)" "unprognostic (5.72e-2)" 10.6 7.5 6.7 31.1 7.1 24.4 4.6 7.1 31.1 2.8 7.5 9.2 11.3 3.5 1.8 3.5 3.1 14.2 4.7 6.9 7.8 3.5 14.6 18.1 27.0 11.4 8.6 1.5 3.2 1.4 3.6 13.9 13.2 4.0 8.6 1.0 4.0 2.5 1.6 4.5 13.5 11.7 9.2 95.2 4.9 1.2 12.1 14.1 2.3 2.7 11.7 9.5 2.6 12.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.0 0.0 5.5 104.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 1.5 45.9 0.0 0.0 0.0 0.2 0.0 88.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 12.8 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 17.1 0.0 845.6 170.3 481.9 226.4 374.2 48.3 18.9 45.5 67.5 159.2 6.4 16.7 52.5 560.5 456.5 387.6 149.7 3.1 197.0 6.7 7.1 7.1 31.1 6.9 7.8 11.4 8.6 13.2 9.2 12.1 12.5 1.0 0.0 7.4 0.3 7.8 0.9 0.1 0.2 0.0 0.0 0.6 1.8 0.6 1.5 0.7 0.0 0.0 0.7 103.5 0.1 0.0 0.1 0.0 0.6 0.2 2.5 0.0 5.7 0.1 0.0 1.2 0.8 0.5 0.7 59.5 0.0 2.2 1.3 114.0 0.0 0.3 0.2 0.0 97.6 24.0 0.4 0.0 90.9 3.6 5.6 36.6 0.0 225.6 1.0 0.0 0.0 0.1 0.0 14.5 0.1 0.0 0.4 0.6 0.1 6.6 0.6 0.5 0.0 0.4 0.2 0.6 1.5 33.2 0.0 0.2 0.2 CD300LG "CLM9, Trem4" ENSG00000161649 "CD300 molecule like family member g" Q6UXG3 17 43847148-43863639 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" Immunity Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 133.6;breast: 111.8;placenta: 58.6" "Cell type enriched" "Detected in some" 11 "Adipocytes: 567.9" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA 1400000 "Cluster 11: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (2.38e-2)" "unprognostic (2.06e-3)" "unprognostic (2.63e-1)" "unprognostic (2.72e-1)" "unprognostic (3.18e-1)" "unprognostic (2.73e-1)" "unprognostic (1.40e-4)" "unprognostic (1.77e-1)" "unprognostic (1.33e-1)" "unprognostic (2.01e-2)" "unprognostic (4.08e-3)" "unprognostic (8.69e-4)" "unprognostic (2.12e-5)" "unprognostic (1.30e-3)" "unprognostic (1.45e-1)" "unprognostic (1.76e-2)" "unprognostic (1.57e-1)" 133.6 2.5 0.1 1.5 0.2 0.2 111.8 0.1 0.2 3.7 0.0 2.5 0.1 4.1 12.7 1.9 4.4 4.5 38.0 0.1 0.1 2.1 1.2 11.3 1.8 0.2 0.3 1.9 2.1 1.1 0.2 58.6 0.2 1.7 0.5 0.0 1.9 2.1 22.1 8.7 2.3 1.1 0.1 2.8 3.1 20.0 0.1 3.4 3.1 47.2 0.2 2.6 3.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.2 0.1 0.1 0.2 0.3 0.2 0.1 0.1 0.1 567.9 0.0 0.0 0.0 0.7 0.1 0.1 0.0 0.6 0.0 1.8 2.3 3.3 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.6 0.0 0.0 50.2 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 5.3 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.3 1.6 13.1 0.6 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 30.9 0.3 0.0 0.0 0.0 0.7 0.0 13.1 2.3 2.9 0.3 0.7 0.1 0.4 0.0 0.3 0.2 0.0 0.0 CD33 "FLJ00391, p67, SIGLEC-3, SIGLEC3" ENSG00000105383 "CD33 molecule" P20138 19 51225064-51243860 "CD markers, FDA approved drug targets, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 32.4;lymphoid tissue: 23.9" "Group enriched" "Detected in some" 6 "granulocytes: 76.0;Hofbauer cells: 78.8;Kupffer cells: 131.2;Langerhans cells: 41.4;Macrophages: 53.5;monocytes: 65.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "classical monocyte: 166.5;intermediate monocyte: 122.0;myeloid DC: 213.5;non-classical monocyte: 57.8" "Group enriched" "Detected in many" 9 "dendritic cells: 213.5;monocytes: 166.5" "Cell line enhanced" "Detected in some" "HEL: 86.1;HL-60: 115.6;HMC-1: 82.4;NB-4: 55.2;RPMI-8226: 62.5;THP-1: 67.0;U-937: 84.1" "CAB011442, HPA035832, HPA064807, CAB079996" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 3400000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Plasma membrane" "CAB011442: , CAB079996: , HPA035832: AB_2674808, HPA064807: AB_2685356" "unprognostic (1.18e-2)" "unprognostic (1.45e-2)" "unprognostic (2.80e-2)" "unprognostic (7.14e-2)" "unprognostic (3.71e-1)" "unprognostic (9.43e-2)" "unprognostic (2.59e-1)" "unprognostic (5.90e-3)" "unprognostic (1.76e-1)" "unprognostic (1.56e-1)" "unprognostic (2.53e-1)" "unprognostic (6.28e-2)" "unprognostic (6.88e-4)" "unprognostic (7.79e-2)" "unprognostic (3.35e-2)" "unprognostic (6.49e-2)" "unprognostic (1.67e-1)" 7.9 3.4 1.1 11.2 1.2 32.4 2.5 1.5 1.6 3.0 2.5 3.2 3.3 1.7 1.3 2.0 2.5 6.6 2.0 1.1 1.8 1.4 5.5 12.6 10.1 2.5 1.6 1.4 1.4 1.2 0.9 6.9 2.4 1.4 4.2 0.2 1.8 2.6 0.9 2.7 4.4 7.1 1.9 23.9 2.3 1.0 2.3 3.5 0.9 0.8 3.5 6.2 1.3 3.6 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.2 0.0 5.5 0.4 0.0 1.3 0.3 0.0 0.2 0.0 0.1 0.1 86.1 0.3 0.0 0.0 115.6 82.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 16.2 21.2 0.2 0.0 0.0 55.2 0.2 0.0 25.9 0.0 4.4 62.5 0.4 0.0 0.2 0.0 0.0 0.1 0.4 0.0 0.0 67.0 0.7 14.0 1.1 1.8 0.1 0.3 7.6 0.2 9.6 84.1 0.4 17.9 166.5 11.0 0.3 122.0 0.4 0.1 0.2 0.5 213.5 0.4 0.3 0.2 20.5 15.5 57.8 6.3 1.1 77.8 1.1 1.2 1.5 1.6 1.1 1.8 2.5 1.6 2.4 1.9 2.3 3.6 0.7 0.0 6.7 0.0 1.0 1.8 0.5 0.0 0.0 0.2 1.4 0.4 0.8 0.0 0.6 0.0 0.0 0.6 0.2 0.1 0.0 0.0 0.7 0.1 0.1 3.0 0.0 4.2 0.0 0.0 0.5 1.1 0.0 0.1 76.0 0.1 5.3 0.7 78.8 0.0 0.0 0.0 0.0 131.2 41.4 1.7 0.3 53.5 1.8 11.2 65.0 0.2 1.0 0.5 0.2 0.0 0.0 0.0 0.3 0.4 0.0 0.2 0.7 0.6 0.0 1.1 0.3 0.7 0.5 0.0 1.0 0.8 2.5 0.1 0.0 0.4 CD68 "DKFZp686M18236, GP110, LAMP4, macrosialin, SCARD1" ENSG00000129226 "CD68 molecule" P34810 17 7579491-7582111 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 358.0;lymphoid tissue: 370.7" "Cell type enhanced" "Detected in many" "Hofbauer cells: 1820.4;Kupffer cells: 701.2;Langerhans cells: 341.5;Macrophages: 791.2;Proximal enterocytes: 335.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 3255.5;intermediate monocyte: 3655.9;non-classical monocyte: 3740.6" "Group enriched" "Detected in all" 11 "dendritic cells: 1378.6;monocytes: 3740.6" "Cell line enhanced" "Detected in all" "ASC diff: 472.0;U-87 MG: 751.0" "Low region specificity" "Detected in all" "CAB000051, CAB000066, HPA048982, CAB072861, CAB072862" Enhanced Supported "Golgi apparatus,Vesicles" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus, Vesicles" "CAB000051: AB_2314148, CAB000066: AB_2074844, CAB072861: AB_2665705, CAB072862: AB_2665706, HPA048982: AB_2680587" "unprognostic (2.16e-2)" "unprognostic (1.47e-2)" "unprognostic (6.46e-2)" "unprognostic (1.49e-3)" "unprognostic (1.78e-2)" "unprognostic (1.97e-1)" "unprognostic (4.75e-4)" "unprognostic (2.83e-2)" "unprognostic (1.31e-1)" "unprognostic (6.85e-2)" "unprognostic (1.04e-1)" "unprognostic (2.59e-1)" "prognostic unfavorable (1.14e-5)" "unprognostic (1.58e-1)" "unprognostic (8.91e-2)" "unprognostic (1.61e-1)" "unprognostic (1.65e-2)" 139.6 78.3 10.4 236.1 9.8 266.2 72.6 11.2 33.4 77.8 14.6 88.8 279.5 26.7 9.0 126.4 43.1 161.1 38.9 8.2 26.7 50.6 156.7 358.0 217.3 45.5 31.2 19.4 22.1 14.2 8.9 173.1 36.0 13.1 91.9 4.8 52.6 19.8 23.0 24.8 240.2 79.0 16.1 370.7 87.5 15.2 58.5 44.2 22.7 21.3 84.2 149.3 50.6 31.6 243.4 48.6 3.2 3.5 472.0 177.6 2.1 75.6 203.9 97.8 113.4 10.1 71.3 2.9 84.2 220.8 174.6 10.6 1.2 47.6 65.9 2.2 9.0 38.8 13.2 59.0 42.0 19.2 207.8 57.1 9.8 205.4 150.4 162.6 26.3 4.3 15.7 24.2 95.5 2.2 1.7 17.2 2.8 63.1 36.0 3.3 4.5 144.4 20.9 10.9 1.6 3.0 63.2 31.3 72.1 2.2 1.6 146.1 82.4 123.7 8.0 125.7 100.1 1.4 2.1 1.9 751.0 46.4 64.0 243.5 3255.5 21.4 9.1 3655.9 11.1 80.2 4.1 6.2 817.3 59.0 5.8 5.1 219.4 18.7 3740.6 1378.6 6.5 3324.3 10.4 9.8 11.2 33.4 8.2 26.7 45.5 31.2 36.0 16.1 58.5 31.6 10.4 0.0 19.7 1.3 20.5 15.7 39.0 58.8 3.4 0.2 7.2 9.8 0.0 12.8 53.2 5.5 0.0 8.9 110.3 22.5 5.9 82.1 0.8 8.3 11.3 15.9 4.9 6.6 0.3 156.8 58.1 45.6 29.6 18.7 43.6 0.9 16.4 23.9 1820.4 0.0 0.4 15.8 16.2 701.2 341.5 2.1 6.5 791.2 39.2 5.6 179.2 0.3 7.2 0.0 0.1 121.0 86.1 1.9 8.5 33.3 335.3 50.2 20.6 1.0 26.3 8.7 11.7 0.5 1.2 12.4 14.3 33.4 10.8 0.5 28.9 99.9 CD74 DHLAG ENSG00000019582 "CD74 molecule" P04233 5 150400041-150412969 "Cancer-related genes, CD markers, Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Adaptive immunity, Immunity" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 5258.9" "Cell type enhanced" "Detected in many" "B-cells: 10167.0;Kupffer cells: 5201.6;Langerhans cells: 23363.4;Macrophages: 7290.2;monocytes: 10305.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 11041.2;intermediate monocyte: 15961.1;memory B-cell: 26889.3;myeloid DC: 23750.6;naive B-cell: 27930.3;non-classical monocyte: 8003.3;plasmacytoid DC: 16940.0" "Group enriched" "Detected in all" 6 "B-cells: 27930.3;dendritic cells: 23750.6;monocytes: 15961.1" "Cell line enhanced" "Detected in many" "CAPAN-2: 2171.7;Daudi: 3523.2;HDLM-2: 4787.6;REH: 3026.0;RPMI-8226: 2014.2;U-266/70: 1443.4;U-698: 1978.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002506, HPA010592, CAB079994" Enhanced Supported "Golgi apparatus" NA NA 210000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 41: Macrophages - Immune response" "Golgi apparatus" "CAB002506: AB_563630, CAB079994: , HPA010592: AB_1078482" "prognostic favorable (1.06e-4)" "unprognostic (1.48e-2)" "unprognostic (4.80e-3)" "prognostic favorable (6.53e-6)" "unprognostic (1.41e-1)" "unprognostic (4.53e-2)" "unprognostic (2.05e-1)" "unprognostic (3.69e-3)" "unprognostic (1.54e-2)" "unprognostic (3.48e-2)" "unprognostic (2.20e-2)" "unprognostic (2.64e-1)" "unprognostic (5.44e-3)" "unprognostic (1.73e-1)" "unprognostic (4.95e-2)" "unprognostic (2.05e-1)" "unprognostic (4.24e-2)" 1512.1 976.5 338.1 2741.2 301.9 984.3 1157.2 365.5 474.4 1562.8 429.1 992.3 1826.2 593.6 490.6 618.8 1139.0 1477.9 604.0 306.7 506.8 1271.1 1142.0 3786.3 4995.6 598.7 431.8 464.3 392.4 390.6 469.3 305.7 533.4 556.7 1155.8 58.1 1999.3 911.8 307.2 682.4 2438.8 1014.2 514.2 4897.4 1511.5 207.5 514.4 2160.2 853.5 374.2 5258.9 1557.5 483.5 771.8 35.7 0.3 1.5 2.4 2.3 2.5 11.0 0.0 0.0 0.7 0.6 443.0 2171.7 3523.2 124.2 0.0 9.2 9.4 0.0 0.0 0.1 4787.6 0.0 109.1 1.2 250.2 6.6 9.2 6.5 24.5 0.0 0.8 0.0 0.6 0.0 0.0 8.0 1270.7 0.4 0.0 4.2 14.0 5.3 0.0 0.1 3026.0 5.2 2014.2 9.0 133.5 5.1 8.2 5.5 4.7 94.9 19.2 81.2 414.4 5.6 10.3 9.9 9.0 4.5 1443.4 170.7 1978.6 745.9 154.2 678.6 410.8 11041.2 3996.9 808.7 15961.1 899.9 26889.3 688.4 1188.4 23750.6 27930.3 378.9 646.6 839.6 2378.1 8003.3 16940.0 2157.2 17779.7 338.1 301.9 365.5 474.4 306.7 506.8 598.7 431.8 533.4 514.2 514.4 771.8 2080.4 419.9 2160.4 0.7 10167.0 715.9 154.0 762.2 398.4 1.7 220.3 437.5 69.6 401.7 1063.3 502.1 0.0 28.3 3199.0 139.7 117.4 1264.4 10.4 111.3 11.5 1787.6 242.9 562.5 0.7 527.5 32.6 278.6 538.2 85.5 417.2 113.4 514.7 52.5 4361.8 1.7 0.6 475.7 390.6 5201.6 23363.4 31.3 117.1 7290.2 1197.1 137.7 10305.9 16.8 403.7 0.5 1.4 384.2 487.3 17.7 2068.3 174.9 5034.4 815.8 1153.1 10.0 164.3 45.1 146.7 2.8 12.6 170.9 575.8 41.6 790.7 12.9 450.7 743.4 CD93 "C1qR(P), C1QR1, C1qRP, CDw93, dJ737E23.1, ECSM3, MXRA4" ENSG00000125810 "CD93 molecule" Q9NPY3 20 23079360-23086324 "CD markers, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 137.6" "Cell type enhanced" "Detected in many" "Adipocytes: 321.5;Endothelial cells: 309.2;Hepatic stellate cells: 162.8;Kupffer cells: 156.4;Macrophages: 102.4;monocytes: 131.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 15 "classical monocyte: 25.8;intermediate monocyte: 16.8;myeloid DC: 9.1;neutrophil: 27.8;non-classical monocyte: 7.5" "Group enriched" "Detected in many" 41 "dendritic cells: 9.1;granulocytes: 27.8;monocytes: 25.8" "Group enriched" "Detected in some" 4 "HUVEC TERT2: 346.0;TIME: 442.2;U-937: 593.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009300, HPA012368" Enhanced Approved "Vesicles,Plasma membrane" NA NA 550000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 32: U-937 - Innate immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Vesicles, Plasma membrane" "HPA009300: AB_1846342, HPA012368: AB_1846341" "unprognostic (2.05e-1)" "unprognostic (2.85e-1)" "unprognostic (1.07e-1)" "unprognostic (4.83e-2)" "unprognostic (2.31e-1)" "unprognostic (2.66e-2)" "unprognostic (6.45e-2)" "unprognostic (2.77e-1)" "unprognostic (4.51e-1)" "unprognostic (3.74e-2)" "unprognostic (2.61e-1)" "unprognostic (1.81e-1)" "prognostic unfavorable (2.74e-4)" "unprognostic (8.81e-3)" "unprognostic (6.13e-2)" "unprognostic (4.49e-2)" "unprognostic (3.11e-2)" 81.4 11.9 2.7 43.5 2.6 16.4 41.0 2.8 6.5 23.9 6.5 13.8 9.8 17.8 6.1 19.0 23.4 39.7 34.3 2.7 3.5 25.6 16.3 64.6 14.0 5.4 4.3 6.2 13.2 10.8 6.6 137.6 5.4 11.3 12.1 1.4 9.7 10.9 24.2 12.2 14.5 43.5 4.0 23.4 13.0 4.6 7.1 9.3 21.4 34.4 10.6 41.3 12.8 3.5 0.2 0.0 4.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 346.0 0.0 0.9 0.0 0.0 0.0 0.0 13.1 0.0 0.0 0.0 0.9 0.2 27.8 0.0 0.0 0.0 0.1 0.2 0.0 0.3 0.0 0.0 105.3 442.2 0.0 0.1 0.1 0.5 0.0 0.0 0.3 0.0 593.5 0.1 0.0 25.8 0.4 0.3 16.8 0.0 0.0 0.2 0.1 9.1 0.0 0.0 0.0 27.8 0.1 7.5 1.2 0.5 9.9 2.7 2.6 2.8 6.5 2.7 3.5 5.4 4.3 5.4 4.0 7.1 3.5 321.5 3.2 7.4 0.0 2.4 15.0 1.0 0.0 6.2 0.0 1.0 1.8 14.3 5.7 3.7 0.0 0.0 0.2 5.0 0.0 0.0 0.5 0.4 0.4 0.7 309.2 0.0 1.3 0.0 0.0 0.5 9.8 0.5 0.4 5.1 0.0 162.8 1.9 19.9 0.0 0.2 0.0 0.0 156.4 52.5 0.8 1.8 102.4 8.8 4.7 131.8 0.2 6.2 0.0 0.1 0.1 0.0 27.8 2.1 4.1 0.0 0.3 3.0 0.1 19.7 5.7 8.0 0.0 0.2 1.6 10.1 0.4 2.4 3.0 0.0 4.0 CDC25C "CDC25, PPP1R60" ENSG00000158402 "Cell division cycle 25C" P30307 5 138285269-138338355 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Host-virus interaction, Mitosis" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.8;lymphoid tissue: 8.9;testis: 18.1" "Cell type enhanced" "Detected in many" "Early spermatids: 41.4;Late spermatids: 42.1;Spermatocytes: 53.6;Spermatogonia: 13.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "CAB003800, HPA066991" Approved Enhanced "Nuclear speckles" No Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear speckles" "CAB003800: AB_562081, HPA066991: AB_2685760" "unprognostic (2.45e-3)" "unprognostic (5.89e-3)" "prognostic favorable (2.49e-4)" "unprognostic (9.72e-3)" "unprognostic (2.17e-1)" "unprognostic (1.53e-1)" "prognostic unfavorable (3.03e-6)" "prognostic unfavorable (4.38e-4)" "unprognostic (5.56e-2)" "unprognostic (2.08e-1)" "unprognostic (1.70e-3)" "unprognostic (1.00e-1)" "unprognostic (0.00e+0)" "unprognostic (5.04e-2)" "unprognostic (1.43e-1)" "unprognostic (2.59e-1)" "unprognostic (3.06e-1)" 0.2 0.2 0.2 2.1 0.2 5.8 0.7 0.3 0.3 0.3 0.2 3.4 3.0 0.4 0.2 1.4 0.2 0.2 0.1 0.2 0.2 0.1 0.5 0.3 3.2 0.2 0.3 0.0 0.4 0.1 0.1 1.2 0.2 0.2 4.1 0.1 0.3 0.1 0.0 1.4 3.0 0.8 0.1 0.9 1.1 18.1 0.2 8.9 0.1 0.0 4.6 0.5 0.5 0.2 27.9 11.0 38.4 28.9 0.9 3.6 9.9 16.4 17.5 36.2 50.3 27.3 52.8 13.3 13.8 10.1 40.5 14.9 31.7 25.9 34.9 11.1 21.5 9.6 15.0 21.2 0.3 6.3 10.0 0.8 0.9 22.0 18.0 3.8 24.6 28.9 14.8 24.2 22.9 15.5 19.3 16.7 9.7 22.3 12.2 11.9 34.2 15.0 6.4 8.4 19.2 11.9 36.8 11.0 16.9 32.6 18.7 13.9 7.2 19.9 16.8 13.9 26.5 15.0 13.4 13.0 8.3 14.3 15.6 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.6 0.1 0.2 0.2 0.3 0.3 0.2 0.2 0.2 0.3 0.2 0.1 0.2 0.2 0.1 0.0 0.0 1.3 0.9 0.6 0.3 1.1 1.8 0.0 0.9 0.8 0.3 0.0 0.2 0.0 0.0 5.0 0.5 1.8 0.0 0.1 41.4 0.4 0.9 0.6 0.0 9.5 1.3 0.0 6.9 1.1 3.6 1.2 0.0 5.5 1.4 0.4 2.7 0.0 1.0 3.9 2.0 0.6 0.5 42.1 1.8 1.2 0.0 1.0 0.6 0.0 0.0 1.0 0.3 0.0 1.4 0.4 4.5 0.3 0.9 0.1 0.1 0.0 0.0 0.2 0.9 53.6 13.0 4.3 0.4 1.4 0.6 0.2 4.9 0.6 CDCA3 "GRCC8, TOME-1" ENSG00000111665 "Cell division cycle associated 3" Q99618 12 6844793-6851292 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 30.5;retina: 66.3" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 56.3;Erythroid cells: 46.5;Extravillous trophoblasts: 74.1;Proximal enterocytes: 65.5;Spermatocytes: 71.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "T-reg: 4.3" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA026587 Approved Cytosol NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA026587: AB_1846386" "unprognostic (3.05e-1)" "unprognostic (1.32e-1)" "unprognostic (9.85e-2)" "unprognostic (1.63e-2)" "unprognostic (2.42e-1)" "unprognostic (7.41e-2)" "prognostic unfavorable (6.51e-5)" "prognostic unfavorable (9.77e-5)" "unprognostic (3.88e-2)" "unprognostic (1.27e-1)" "unprognostic (1.80e-3)" "unprognostic (8.81e-2)" "unprognostic (0.00e+0)" "unprognostic (1.22e-1)" "unprognostic (1.09e-1)" "unprognostic (2.11e-1)" "unprognostic (4.94e-2)" 1.2 2.6 0.7 7.3 0.5 16.0 1.2 1.0 1.0 4.4 0.3 6.1 20.7 2.9 0.4 9.0 1.9 1.1 2.8 0.6 0.6 1.6 1.6 1.7 17.2 0.7 0.7 4.6 1.1 0.4 8.6 4.7 0.6 3.1 7.8 66.3 2.5 0.3 0.5 6.3 18.5 3.0 0.4 4.6 3.2 21.4 0.6 30.5 1.8 0.2 23.4 2.2 4.0 0.5 106.8 88.8 81.0 45.1 4.3 6.8 95.0 71.7 46.4 119.5 83.3 142.7 86.9 64.9 8.6 54.9 86.9 71.0 53.3 55.0 117.0 97.2 60.9 56.8 58.9 81.7 0.5 41.3 47.2 3.1 3.9 63.0 34.6 27.9 50.9 44.2 47.8 36.4 116.7 94.1 60.0 46.0 86.2 75.8 62.3 57.6 68.5 34.3 40.2 36.4 12.2 23.6 61.8 53.5 18.7 87.0 21.9 38.6 22.3 52.6 67.2 35.0 117.2 19.7 21.5 104.2 25.4 53.6 92.0 0.0 0.2 0.0 0.1 0.1 0.3 0.7 0.7 0.8 0.2 0.2 0.2 0.4 0.2 0.4 0.3 1.1 4.3 0.5 0.7 0.5 1.0 1.0 0.6 0.6 0.7 0.7 0.6 0.4 0.6 0.5 0.7 0.0 0.5 0.7 4.1 2.9 1.7 5.0 2.2 12.3 1.9 2.5 1.2 1.5 1.1 0.0 56.3 29.5 0.9 6.9 0.0 1.1 12.4 1.8 2.3 1.7 1.2 46.5 0.5 0.4 74.1 5.2 4.6 2.3 4.5 15.2 3.9 1.6 19.3 6.7 0.6 11.9 4.1 4.0 3.1 6.8 1.8 3.5 0.0 1.0 1.1 1.1 1.0 0.5 0.5 0.4 4.0 0.4 19.2 1.4 65.5 0.9 0.4 18.0 6.6 0.5 8.3 71.5 14.8 12.6 1.8 8.5 4.6 1.4 17.4 2.6 CDCA7L "JPO2, R1, RAM2" ENSG00000164649 "Cell division cycle associated 7 like" Q96GN5 7 21900899-21945903 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 51.0;Spermatogonia: 63.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 101.0;naive B-cell: 124.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 4 "olfactory bulb: 10.1" "HPA027169, HPA074623" Approved Supported Nucleoplasm,Nucleoli,Cytosol No Yes "Cluster 21: B-cells - Adaptive immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Nucleoli" Cytosol "HPA027169: AB_1856058, HPA074623: " "unprognostic (5.13e-3)" "unprognostic (5.94e-2)" "unprognostic (1.91e-1)" "unprognostic (4.63e-2)" "unprognostic (2.33e-1)" "unprognostic (2.15e-1)" "prognostic unfavorable (4.36e-6)" "unprognostic (4.09e-2)" "unprognostic (2.86e-1)" "unprognostic (3.87e-2)" "unprognostic (3.22e-2)" "unprognostic (2.34e-1)" "prognostic unfavorable (1.98e-4)" "unprognostic (2.00e-1)" "unprognostic (1.60e-1)" "unprognostic (1.73e-1)" "unprognostic (2.83e-3)" 5.9 1.4 3.9 15.0 9.1 51.7 15.7 5.7 5.2 8.7 17.8 17.0 10.7 13.8 5.5 11.2 11.5 8.1 25.3 3.9 3.5 2.8 4.8 14.0 37.1 6.9 4.8 21.8 13.0 1.8 1.1 4.7 3.8 7.3 19.0 5.1 9.0 7.6 6.2 18.5 13.6 11.9 5.0 13.3 17.8 18.5 7.8 49.0 29.8 3.4 31.8 6.3 8.1 9.8 84.5 27.6 26.0 0.6 14.5 17.9 0.0 65.9 58.2 51.8 73.5 11.3 75.4 173.6 21.8 59.3 102.4 51.1 41.4 69.4 103.6 0.3 28.6 42.3 83.8 7.4 21.1 111.1 0.4 35.2 12.7 40.0 116.9 54.9 104.8 133.5 58.3 0.1 41.4 34.5 146.1 46.1 153.2 17.4 36.2 141.0 94.0 119.8 15.4 14.8 96.9 79.7 30.3 19.9 29.9 34.4 45.6 54.6 43.0 57.1 68.5 101.3 83.8 90.6 63.6 223.0 55.7 154.6 54.5 1.1 2.3 43.2 2.2 3.8 0.3 101.0 6.4 3.2 14.9 124.5 30.9 12.8 3.8 3.4 4.9 75.9 9.9 12.2 3.9 9.1 5.7 5.2 3.9 3.5 6.9 4.8 3.8 5.0 7.8 9.8 1.0 19.2 31.5 7.5 51.0 27.1 23.7 6.9 17.1 1.5 12.5 20.7 38.7 11.5 19.0 0.0 2.1 0.5 30.7 8.4 3.9 8.9 7.3 5.4 2.7 4.8 10.7 21.9 0.5 6.2 0.3 13.4 18.3 5.3 8.8 14.9 1.4 4.0 10.8 13.5 1.0 26.1 8.2 15.2 3.5 5.2 4.1 7.0 8.8 1.9 1.6 2.4 1.0 15.1 8.7 3.9 7.4 2.6 20.2 14.2 1.5 0.1 4.2 2.7 13.1 6.8 12.4 4.6 63.5 9.6 7.7 0.3 5.4 8.3 23.0 6.2 CDCA8 "BOR, DasraB, FLJ12042, MESRGP" ENSG00000134690 "Cell division cycle associated 8" Q53HL2 1 37692481-37709719 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 33.5;lymphoid tissue: 38.8;testis: 22.5" "Cell type enhanced" "Detected in many" "Erythroid cells: 34.1;Extravillous trophoblasts: 26.0;Spermatocytes: 76.8;Spermatogonia: 42.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA028120, HPA028258, HPA028783, CAB040294" Enhanced Supported "Nucleoplasm,Nucleoli,Cytokinetic bridge" Yes Yes "Cluster 27: Non-specific - Gene expression" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoli "Nucleoplasm, Cytokinetic bridge" "CAB040294: , HPA028120: AB_10670556, HPA028258: AB_10669864, HPA028783: AB_10671092" "unprognostic (8.36e-2)" "unprognostic (2.00e-1)" "unprognostic (8.39e-2)" "unprognostic (7.75e-3)" "unprognostic (2.34e-1)" "unprognostic (5.42e-2)" "prognostic unfavorable (4.93e-10)" "unprognostic (4.30e-3)" "prognostic unfavorable (6.04e-4)" "unprognostic (3.00e-1)" "prognostic unfavorable (8.32e-4)" "unprognostic (3.78e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (6.39e-3)" "unprognostic (2.99e-1)" "unprognostic (3.18e-1)" "unprognostic (1.67e-1)" 1.0 1.1 0.7 7.9 1.0 33.5 2.0 0.2 0.9 1.7 0.0 9.4 8.3 1.3 1.8 9.2 1.0 1.1 0.6 0.5 0.4 0.8 1.3 1.5 19.5 0.6 0.4 0.6 0.8 0.5 0.6 4.4 0.5 0.7 11.3 1.9 1.8 0.5 0.3 6.3 7.3 2.8 0.3 4.9 4.9 22.5 0.6 38.8 0.6 0.5 22.7 2.0 2.9 0.7 108.5 45.5 84.4 62.1 3.6 7.0 57.2 79.6 39.5 137.2 96.6 71.9 78.8 130.2 31.5 50.5 54.5 59.4 97.8 52.4 141.9 86.8 44.9 116.8 49.2 57.3 0.8 113.8 58.4 2.8 3.8 77.1 67.3 15.3 60.9 91.1 100.7 135.6 99.1 47.7 106.1 68.9 98.8 61.7 62.8 102.2 115.6 74.4 31.0 43.8 75.4 33.3 87.5 40.6 52.4 71.7 60.1 42.4 37.3 67.8 70.6 39.2 126.0 91.4 128.1 176.3 31.6 104.7 79.6 0.0 0.7 1.3 1.5 1.6 2.8 1.7 3.6 2.2 0.7 1.4 1.1 2.3 3.0 4.1 3.9 1.2 5.9 1.7 0.7 1.0 0.2 0.9 0.5 0.4 0.6 0.4 0.5 0.3 0.6 0.7 0.8 0.0 0.5 1.3 4.8 3.3 0.8 2.4 1.8 1.3 1.9 1.5 0.7 2.8 0.4 0.0 0.0 17.1 1.9 12.4 0.0 1.2 1.0 1.7 1.6 1.9 3.6 34.1 1.2 0.6 26.0 2.9 6.6 2.5 0.0 12.0 3.6 1.0 11.6 1.7 0.9 8.2 2.0 3.5 1.9 2.8 1.5 3.7 1.8 0.0 1.6 0.1 2.1 0.5 0.9 2.4 4.0 1.2 15.8 1.3 1.9 0.6 4.7 1.0 19.7 0.2 6.3 76.8 42.0 17.1 2.7 2.9 5.5 1.2 13.2 1.2 CDH11 "CAD11, OB" ENSG00000140937 "Cadherin 11" P55287 16 64943753-65126112 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes, Deafness, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 178.2;placenta: 122.2" "Cell type enhanced" "Detected in many" "Astrocytes: 93.0;Endometrial stromal cells: 125.0;Excitatory neurons: 122.2;Fibroblasts: 102.2;Microglial cells: 145.2;Oligodendrocyte precursor cells: 158.3;Oligodendrocytes: 106.3;Theca cells: 160.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 246.5;BJ hTERT+: 139.3;fHDF/TERT166: 332.3;HSkMC: 217.4;PC-3: 291.2;U-2197: 194.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB013072 Enhanced NA Yes 4800000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "CAB013072: AB_2533068" "unprognostic (1.77e-1)" "unprognostic (1.51e-1)" "unprognostic (1.50e-1)" "unprognostic (6.93e-2)" "unprognostic (6.00e-2)" "unprognostic (1.02e-1)" "unprognostic (6.96e-2)" "unprognostic (1.28e-1)" "unprognostic (2.09e-1)" "unprognostic (2.30e-2)" "unprognostic (3.74e-2)" "unprognostic (6.75e-2)" "prognostic unfavorable (2.48e-9)" "unprognostic (1.43e-3)" "unprognostic (3.20e-2)" "unprognostic (1.26e-1)" "unprognostic (5.07e-3)" 15.1 8.6 12.4 25.7 27.9 0.3 10.7 10.8 15.8 57.7 13.8 11.4 7.0 52.8 9.5 7.4 12.5 58.6 10.2 19.2 21.4 10.2 1.8 45.6 17.5 17.1 24.1 178.2 3.4 2.6 10.4 122.2 17.3 20.0 12.2 14.0 12.7 24.3 2.6 10.9 8.9 54.3 21.1 89.3 11.8 8.0 19.3 3.7 8.1 3.1 13.0 47.6 13.6 21.4 0.2 0.0 51.4 0.1 35.7 77.5 0.3 246.5 139.3 61.0 34.5 4.6 0.2 0.0 0.0 332.3 0.0 0.1 0.1 1.7 43.4 0.0 2.1 0.0 1.4 0.0 29.7 0.0 14.4 217.4 0.1 74.7 14.9 0.0 17.4 0.0 0.0 0.0 33.1 0.3 0.1 0.3 19.2 37.4 291.2 0.8 38.0 0.0 0.0 0.0 0.8 36.0 0.1 0.3 0.2 64.5 0.3 0.1 0.0 124.4 17.2 194.0 70.1 0.0 0.0 0.1 21.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 27.9 10.8 15.8 19.2 21.4 17.1 24.1 17.3 21.1 19.3 21.4 11.4 3.2 0.0 93.0 0.1 3.8 1.0 7.9 0.0 19.9 1.0 7.4 3.1 1.5 3.3 0.0 0.0 2.6 0.2 0.1 0.0 0.1 2.7 3.9 125.0 17.8 0.0 2.7 122.2 0.0 2.3 102.2 0.5 2.7 0.0 60.0 68.9 0.0 4.7 0.0 67.6 0.6 0.0 0.6 6.9 4.2 52.5 0.9 5.4 145.2 0.0 41.9 0.0 158.3 106.3 0.8 0.0 77.5 0.0 1.6 0.0 1.4 0.4 2.1 26.3 12.8 38.0 1.7 1.1 0.5 3.1 5.6 1.1 160.2 0.3 0.5 CDH12 "Br-cadherin, CDHB" ENSG00000154162 "Cadherin 12" P55289 5 21750673-22853344 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.6;retina: 11.6" "Group enriched" "Detected in some" 15 "Excitatory neurons: 859.5;Inhibitory neurons: 887.7" "Low cancer specificity" "Detected in some" "Group enriched" "Detected in some" 5 "basal ganglia: 6.6;cerebral cortex: 3.8;hippocampal formation: 2.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "PC-3: 2.2;SCLC-21H: 3.1;U-2 OS: 1.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029325 Uncertain Uncertain Vesicles NA NA "Cluster 77: Retina - Visual perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA029325: AB_2672998" "unprognostic (2.38e-1)" "unprognostic (3.21e-1)" "unprognostic (4.95e-2)" "unprognostic (8.61e-2)" "unprognostic (3.31e-2)" "unprognostic (3.91e-1)" "unprognostic (2.72e-1)" "unprognostic (3.26e-2)" "unprognostic (1.34e-1)" "unprognostic (3.51e-2)" "unprognostic (3.25e-4)" "unprognostic (7.35e-2)" "unprognostic (3.48e-2)" "unprognostic (5.19e-2)" 0.0 2.0 0.8 0.0 6.6 0.0 0.5 0.2 3.8 3.0 2.1 0.0 0.0 0.3 0.2 0.0 2.2 0.0 0.0 2.0 0.0 0.1 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 1.4 0.1 0.8 0.0 0.1 11.6 1.4 0.2 0.0 0.8 0.0 0.2 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.1 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 6.6 0.2 3.8 2.0 0.0 0.5 0.0 0.8 0.0 0.0 0.7 0.4 0.0 0.0 41.4 0.0 0.1 0.0 0.0 0.0 25.1 0.4 0.6 0.9 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.1 2.1 0.0 0.0 859.5 0.0 0.0 0.2 0.0 0.1 0.0 0.4 0.0 0.0 0.0 20.2 887.7 0.0 0.0 0.0 0.4 0.3 0.3 0.0 0.0 15.9 0.0 2.2 0.0 31.2 41.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.1 0.0 0.2 0.0 2.6 1.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 CDH16 ENSG00000166589 "Cadherin 16" O75309 16 66908122-66918917 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "kidney: 250.0" "Cell type enriched" "Detected in some" 4 "Collecting duct cells: 617.9" "Cancer enriched" "Detected in many" 15 "renal cancer: 96.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 99 "RPTEC TERT1: 225.5" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB013526, HPA036260" Enhanced NA NA 130000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB013526: , HPA036260: AB_2675027" "unprognostic (1.07e-1)" "unprognostic (2.47e-1)" "unprognostic (1.96e-1)" "unprognostic (9.81e-2)" "unprognostic (4.24e-3)" "unprognostic (5.81e-2)" "unprognostic (5.58e-1)" "unprognostic (1.02e-1)" "unprognostic (1.23e-2)" "prognostic favorable (1.02e-7)" "unprognostic (2.19e-1)" "unprognostic (1.99e-1)" "unprognostic (7.36e-3)" "unprognostic (2.34e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.4 1.3 0.3 4.7 0.3 11.0 0.3 0.1 0.0 0.0 250.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 3.9 0.4 0.0 1.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 35.3 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 225.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.1 0.4 6.7 0.0 0.0 617.9 0.0 0.1 0.0 0.4 74.3 0.1 2.9 18.0 2.1 0.2 0.0 0.0 0.0 0.0 0.2 0.7 0.0 34.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 14.6 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.4 1.9 124.4 0.0 0.0 0.0 0.6 0.9 0.0 0.2 1.9 0.0 1.0 0.8 0.0 0.7 0.0 CDH23 "CDHR23, DFNB12, USH1D" ENSG00000107736 "Cadherin related 23" Q9H251 10 71396920-71815947 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Hearing, Sensory transduction, Vision" "Deafness, Disease variant, Non-syndromic deafness, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.6;ovary: 35.3" "Cell type enhanced" "Detected in many" "Early spermatids: 78.4;Late spermatids: 67.7;Microglial cells: 33.7;Muller glia cells: 90.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "intermediate monocyte: 26.8;non-classical monocyte: 38.1;plasmacytoid DC: 9.5" "Lineage enhanced" "Detected in many" "monocytes: 38.1" "Group enriched" "Detected in some" 4 "RT4: 13.4;SCLC-21H: 5.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA017232 Approved NA NA 950000 "Cluster 51: Monocytes - Innate immune response" "Cluster 21: Non-specific - Transcription" "Cluster 15: RT4 - Unknown function" "Cluster 5: Muller glia cells - Visual perception" "HPA017232: AB_1845903" "unprognostic (6.76e-2)" "unprognostic (2.86e-3)" "unprognostic (3.82e-2)" "unprognostic (3.13e-3)" "unprognostic (1.07e-1)" "unprognostic (5.52e-2)" "unprognostic (7.93e-2)" "unprognostic (2.88e-1)" "unprognostic (6.44e-3)" "unprognostic (4.67e-2)" "unprognostic (2.05e-1)" "unprognostic (9.23e-3)" "unprognostic (2.14e-3)" "unprognostic (2.33e-2)" "unprognostic (1.72e-1)" "unprognostic (1.70e-2)" "prognostic favorable (3.40e-4)" 11.3 3.3 9.6 2.1 11.6 2.2 6.2 10.6 7.9 3.3 10.2 1.7 1.1 4.9 1.6 1.8 8.9 2.2 5.4 6.3 16.2 0.9 14.4 7.8 1.7 35.6 18.5 35.3 8.4 9.9 1.2 0.5 34.7 3.7 1.2 14.4 1.2 0.7 2.7 1.6 2.3 2.1 8.6 7.0 1.7 11.0 23.6 5.3 1.8 2.5 1.4 4.2 2.6 8.8 0.0 0.7 0.8 1.3 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.0 0.9 0.4 1.3 0.0 0.0 0.1 1.2 1.3 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.0 0.2 0.1 1.5 0.4 0.0 1.1 0.0 0.1 0.0 13.4 5.3 1.1 0.8 0.2 0.1 1.1 0.1 2.2 0.0 0.0 1.1 0.0 0.0 0.6 0.0 0.2 1.5 1.0 0.0 0.0 6.0 5.1 0.1 26.8 0.4 0.0 0.2 0.1 4.9 0.0 0.2 0.6 6.1 0.0 38.1 9.5 0.0 2.9 9.6 11.6 10.6 7.9 6.3 16.2 35.6 18.5 34.7 8.6 23.6 8.8 8.2 0.0 0.6 9.4 1.1 0.8 4.1 0.3 0.6 1.9 0.2 1.1 4.7 0.0 1.0 1.8 0.0 1.5 11.5 0.9 0.0 0.4 78.4 1.9 0.7 10.0 7.2 0.0 1.1 0.4 4.4 3.4 1.1 0.3 0.0 0.4 7.9 20.4 2.2 0.0 2.7 1.1 0.0 12.2 11.6 67.7 2.5 15.0 7.2 33.7 10.6 90.7 3.1 1.5 8.5 0.2 7.5 0.7 0.4 2.6 1.6 0.8 0.7 4.2 6.6 5.1 1.7 3.4 1.0 0.0 1.1 0.3 1.0 0.2 0.7 3.6 CDHR2 "FLJ20124, FLJ20383, PC-LKC, PCDH24, PCLKC" ENSG00000074276 "Cadherin related family member 2" Q9BYE9 5 176542511-176595974 "Plasma proteins, Predicted membrane proteins" "Cell adhesion, Differentiation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "intestine: 275.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 167.0;Early spermatids: 182.4;Late spermatids: 680.0;Paneth cells: 215.0;Proximal enterocytes: 611.4" "Group enriched" "Detected in many" 14 "colorectal cancer: 9.1;liver cancer: 5.7;pancreatic cancer: 11.7;renal cancer: 8.6;stomach cancer: 9.7" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 17 "Hep G2: 22.2" "Region enriched" "Detected in single" 6 "hypothalamus: 2.1" "Low region specificity" "Detected in all" "HPA012569, HPA017053" Enhanced NA NA 8800000 "Cluster 56: Intestine - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 45: Enterocytes - Digestion" "HPA012569: AB_1845298, HPA017053: AB_1845297" "unprognostic (1.34e-2)" "unprognostic (8.90e-4)" "unprognostic (3.82e-2)" "unprognostic (8.51e-2)" "unprognostic (5.10e-4)" "unprognostic (4.24e-3)" "unprognostic (6.66e-2)" "unprognostic (2.06e-3)" "unprognostic (1.54e-1)" "unprognostic (1.99e-1)" "unprognostic (7.66e-3)" "unprognostic (1.75e-1)" "prognostic favorable (9.29e-4)" "unprognostic (6.58e-2)" "unprognostic (3.55e-1)" "unprognostic (2.30e-2)" "unprognostic (1.42e-1)" 0.0 0.1 0.8 4.5 0.4 0.2 0.0 0.1 0.7 0.0 0.0 23.2 275.8 0.1 0.0 0.1 0.6 5.0 0.0 1.2 0.4 10.1 30.3 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 12.6 0.3 0.0 0.0 0.0 0.1 238.3 1.1 0.0 0.1 12.4 4.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.9 0.2 0.2 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.1 22.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.2 0.5 0.0 0.2 0.0 0.1 0.0 1.3 0.0 0.0 0.3 1.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.4 0.1 0.7 1.2 0.4 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 2.3 1.2 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.6 8.6 0.0 1.8 0.0 0.0 0.3 167.0 0.0 4.0 182.4 3.2 0.1 0.2 33.6 0.0 3.9 1.0 0.0 0.0 55.0 0.1 0.0 0.0 0.0 15.3 0.0 0.0 4.2 42.7 0.0 0.6 0.0 680.0 1.5 0.5 0.0 1.0 0.0 1.6 0.0 1.5 0.5 15.3 215.0 2.2 0.1 0.0 611.4 13.7 0.7 0.3 0.0 0.0 0.1 3.8 2.0 0.0 0.0 0.1 0.7 3.5 19.8 0.0 CDK17 "PCTAIRE2, PCTK2" ENSG00000059758 "Cyclin dependent kinase 17" Q00537 12 96278261-96400480 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 101.5;Oligodendrocytes: 259.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 134.8;TIME: 160.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015325 Approved Approved Nucleoplasm,Cytosol Yes No "Cluster 38: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Cytosol" "HPA015325: AB_1855090" "unprognostic (4.35e-1)" "unprognostic (2.79e-1)" "unprognostic (2.70e-1)" "unprognostic (3.56e-1)" "unprognostic (1.50e-1)" "unprognostic (4.96e-3)" "unprognostic (5.22e-3)" "unprognostic (1.23e-1)" "unprognostic (3.23e-2)" "unprognostic (2.75e-2)" "unprognostic (2.44e-1)" "unprognostic (5.96e-2)" "prognostic unfavorable (1.09e-6)" "unprognostic (4.97e-3)" "unprognostic (1.72e-1)" "unprognostic (2.92e-2)" "unprognostic (1.70e-2)" 21.4 11.2 26.3 18.9 45.9 48.1 18.4 23.0 34.7 13.2 8.3 17.0 11.9 26.2 9.1 14.6 13.9 16.2 11.4 36.7 28.6 11.6 16.3 20.6 21.7 23.2 23.0 15.7 10.5 10.6 8.0 31.8 23.0 14.0 12.2 19.3 8.7 11.1 8.8 11.0 11.5 29.5 27.4 21.8 10.5 26.6 28.5 24.8 11.6 12.3 22.2 17.1 12.8 54.0 15.4 12.5 32.5 8.9 15.9 41.2 24.1 34.8 46.9 29.1 27.2 7.7 8.8 22.7 23.0 24.5 15.6 13.8 19.8 20.9 39.5 24.9 15.5 32.7 8.5 10.9 34.4 17.9 18.4 30.0 21.3 43.0 77.1 51.8 134.8 18.9 24.7 18.1 66.8 9.5 17.0 28.1 14.4 7.6 22.8 29.2 18.0 19.8 35.1 12.7 17.1 11.7 19.9 18.4 25.9 24.7 14.0 15.7 160.5 25.6 10.0 13.8 18.7 26.0 21.1 24.1 9.6 7.6 19.2 66.7 6.4 17.1 22.2 9.3 24.0 17.5 17.9 25.1 10.0 16.6 25.0 21.7 23.2 31.4 9.0 7.3 15.8 16.6 26.3 45.9 23.0 34.7 36.7 28.6 23.2 23.0 23.0 27.4 28.5 54.0 58.1 16.0 6.5 54.5 37.3 26.8 10.7 8.6 19.4 11.8 13.8 9.8 11.9 7.2 10.3 9.2 16.7 12.0 64.4 7.2 0.0 4.9 3.3 17.6 10.0 51.7 15.0 17.9 101.5 3.6 27.9 24.0 21.4 17.2 18.3 8.9 34.2 10.8 12.1 5.0 59.2 7.9 4.1 14.5 20.7 4.1 9.9 16.7 17.8 64.6 8.6 22.6 32.0 52.3 259.2 7.4 3.4 9.4 64.7 12.5 6.5 8.6 15.4 9.6 6.6 22.7 22.0 8.8 21.6 24.2 25.9 13.7 63.2 10.7 6.0 15.1 CDK19 "bA346C16.3, CDC2L6, CDK11, KIAA1028" ENSG00000155111 "Cyclin dependent kinase 19" Q9BWU1 6 110609978-110815958 "Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 40.8" "Cell type enhanced" "Detected in all" "Late spermatids: 137.1;Oligodendrocyte precursor cells: 154.8;Oligodendrocytes: 476.3" "Cancer enhanced" "Detected in all" "prostate cancer: 23.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 4.6" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007053, HPA007062" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 18: U-2197 - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol Nucleoplasm "HPA007053: AB_1233803, HPA007062: " "unprognostic (1.66e-2)" "unprognostic (1.84e-1)" "unprognostic (3.63e-1)" "unprognostic (3.00e-3)" "unprognostic (1.62e-1)" "unprognostic (2.66e-3)" "prognostic unfavorable (3.56e-4)" "unprognostic (1.47e-2)" "unprognostic (2.96e-2)" "unprognostic (2.00e-3)" "unprognostic (3.94e-1)" "unprognostic (4.04e-1)" "prognostic unfavorable (4.72e-5)" "unprognostic (1.75e-1)" "unprognostic (9.78e-2)" "unprognostic (6.51e-2)" "unprognostic (9.50e-3)" 6.2 3.4 22.7 7.2 32.1 11.7 6.4 17.9 29.0 6.6 7.5 6.9 5.3 10.2 3.8 8.2 5.4 8.3 4.4 20.8 19.3 6.4 5.0 6.7 9.4 28.8 24.7 9.8 3.9 6.5 2.3 11.5 22.7 26.7 6.4 8.8 4.4 5.9 3.3 8.5 6.7 7.3 19.4 8.0 7.1 18.5 26.9 13.6 6.1 5.4 9.2 5.3 6.6 40.8 5.7 6.1 21.8 26.4 11.1 15.6 10.8 18.8 19.4 6.7 8.8 7.6 6.4 14.7 6.5 13.2 13.9 3.2 8.0 3.9 15.4 18.2 4.5 26.0 8.8 8.9 6.8 10.5 18.2 10.7 8.6 9.7 14.1 17.0 6.8 12.3 7.6 20.2 14.5 9.7 14.3 15.0 2.0 8.1 4.1 14.8 11.3 5.8 7.8 11.0 10.6 19.8 14.4 11.3 17.0 7.2 3.9 37.1 7.7 14.2 7.6 29.6 11.4 2.1 3.2 12.8 15.6 13.7 14.9 2.1 1.2 0.9 0.4 0.7 0.4 0.6 0.3 0.3 1.0 0.6 0.2 0.3 4.6 0.7 0.4 0.5 0.4 0.3 22.7 32.1 17.9 29.0 20.8 19.3 28.8 24.7 22.7 19.4 26.9 40.8 15.9 3.2 17.8 50.6 19.2 9.8 14.4 6.7 12.0 19.2 14.6 9.4 8.2 18.6 8.7 16.5 16.7 7.0 17.8 27.0 1.9 10.5 102.3 13.7 16.5 13.6 12.6 21.6 85.3 4.7 18.4 12.0 13.7 25.6 7.0 23.0 20.0 12.2 16.4 23.5 51.5 13.5 8.2 33.9 19.9 137.1 10.8 22.1 26.6 62.8 19.6 33.9 22.6 154.8 476.3 7.0 20.0 16.1 5.9 30.0 16.1 7.7 6.9 13.9 6.6 11.2 12.3 56.6 15.8 20.3 16.2 7.9 13.3 10.1 13.8 11.1 CDK20 "CCRK, p42" ENSG00000156345 "Cyclin dependent kinase 20" Q8IZL9 9 87966441-87974753 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Cell division" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Respiratory ciliated cells: 21.9;Spermatocytes: 30.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 3.6" "Group enriched" "Detected in many" 7 "NK-cells: 3.6;T-cells: 2.3" "Cell line enhanced" "Detected in many" "SCLC-21H: 18.2;THP-1: 29.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA007666, HPA027379, HPA027401" Enhanced Supported Nucleoplasm NA NA "Cluster 15: NK-cells - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 43: THP-1 - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "HPA007666: AB_10600002, HPA027379: AB_10599939, HPA027401: AB_10601553" "unprognostic (4.60e-2)" "unprognostic (6.48e-2)" "unprognostic (1.69e-2)" "prognostic favorable (2.59e-4)" "unprognostic (2.32e-1)" "unprognostic (4.33e-3)" "unprognostic (2.81e-4)" "unprognostic (6.33e-2)" "unprognostic (1.45e-1)" "unprognostic (1.34e-1)" "unprognostic (2.83e-3)" "unprognostic (4.04e-2)" "prognostic favorable (2.12e-5)" "unprognostic (8.24e-3)" "unprognostic (5.77e-2)" "unprognostic (3.83e-2)" "unprognostic (1.42e-2)" 2.9 14.8 8.8 1.5 9.8 1.0 3.1 5.5 9.5 7.2 11.1 6.4 3.5 5.7 3.8 2.3 13.3 3.5 3.4 10.0 10.6 8.3 3.3 3.0 1.2 6.4 6.8 7.8 6.1 8.4 12.7 1.8 6.9 5.2 2.2 8.4 3.3 5.5 1.0 3.3 4.8 3.6 6.1 1.4 4.4 15.9 10.9 1.3 5.3 1.3 0.5 7.6 3.7 7.1 3.1 3.6 3.2 9.5 2.6 3.5 1.2 2.7 5.4 7.7 6.9 1.1 4.6 0.0 3.7 4.6 13.0 3.7 0.0 2.8 3.2 7.3 3.2 0.0 1.9 0.0 9.2 3.7 4.4 2.6 5.5 12.0 5.1 5.9 0.0 6.7 0.4 0.0 2.2 9.1 2.2 1.2 2.4 7.2 1.1 0.0 0.0 0.1 9.6 2.8 18.2 5.2 2.9 3.9 4.9 1.1 3.9 29.8 0.0 3.4 1.3 0.6 3.0 4.2 4.6 0.0 11.7 2.4 3.5 0.0 0.3 0.2 0.6 0.4 0.3 0.0 1.4 1.0 0.3 0.0 2.3 1.6 0.0 3.6 0.3 0.3 1.5 0.6 8.8 9.8 5.5 9.5 10.0 10.6 6.4 6.8 6.9 6.1 10.9 7.1 0.3 3.2 4.4 5.2 0.2 2.2 2.3 2.2 5.7 6.1 3.0 3.2 2.0 2.8 4.0 1.8 2.1 4.6 0.8 5.8 1.9 5.2 6.3 15.8 6.7 0.8 0.0 0.8 8.3 1.5 2.3 3.4 4.1 5.8 1.3 4.0 0.7 0.8 0.9 8.4 6.7 2.8 4.1 0.0 0.2 4.3 4.4 1.1 0.0 1.0 0.3 5.0 2.1 3.0 2.9 1.4 1.6 6.8 0.3 3.0 7.3 6.3 21.9 15.0 6.6 1.1 3.2 30.2 3.4 0.8 2.3 4.0 1.1 11.6 3.4 1.2 CDK6 PLSTIRE ENSG00000105810 "Cyclin dependent kinase 6" Q00534 7 92604921-92836573 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, FDA approved drug targets, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 41.1" "Cell type enhanced" "Detected in many" "Early spermatids: 215.9;Erythroid cells: 213.5;Late spermatids: 237.0;Oligodendrocytes: 235.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "MOLT-4: 378.4;REH: 173.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA002637, CAB004363" Enhanced Supported Nucleoplasm,Cytosol NA NA 26000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 34: Spermatids - Unknown function" Nucleoplasm Cytosol "CAB004363: AB_627242, HPA002637: AB_1846432" "unprognostic (1.29e-1)" "unprognostic (5.98e-3)" "unprognostic (9.07e-2)" "unprognostic (2.78e-3)" "unprognostic (2.56e-2)" "unprognostic (3.24e-2)" "unprognostic (3.39e-1)" "unprognostic (2.42e-3)" "unprognostic (7.19e-2)" "unprognostic (7.78e-3)" "prognostic unfavorable (3.86e-6)" "unprognostic (4.06e-2)" "unprognostic (4.09e-3)" "unprognostic (1.09e-1)" "unprognostic (7.88e-2)" "unprognostic (1.93e-1)" "prognostic unfavorable (2.33e-5)" 3.7 7.3 6.7 4.7 7.1 18.1 4.9 5.4 5.1 4.8 2.6 5.9 6.1 3.1 2.1 4.2 2.9 3.6 4.7 4.0 5.0 4.4 5.9 4.1 6.6 6.3 6.7 2.7 6.2 9.9 1.7 17.3 6.3 3.0 7.5 0.5 5.7 4.2 1.0 6.8 7.2 3.2 5.8 4.9 9.1 3.3 9.6 41.1 2.4 2.3 6.2 3.8 4.6 8.8 27.1 11.3 34.9 23.9 10.6 11.5 5.8 27.2 18.4 14.3 13.5 34.7 20.9 21.7 14.4 19.9 8.4 15.8 20.8 42.6 34.4 43.0 10.6 50.8 23.3 34.7 6.3 33.0 2.7 11.5 23.1 17.9 90.8 13.4 5.6 75.1 49.3 55.5 26.7 5.9 378.4 3.8 9.8 37.4 9.1 173.7 112.0 36.4 20.3 0.7 18.1 113.8 3.7 9.8 17.1 26.0 0.6 54.9 19.3 44.1 63.7 18.0 54.2 27.4 0.5 27.6 6.9 112.1 60.8 0.9 0.2 0.6 0.6 0.4 0.9 0.2 0.6 0.8 0.5 0.3 0.7 0.7 0.1 0.7 0.4 0.9 0.3 0.3 6.7 7.1 5.4 5.1 4.0 5.0 6.3 6.7 6.3 5.8 9.6 8.8 38.6 25.6 3.7 2.9 17.7 60.3 23.5 55.0 62.6 0.4 20.7 21.2 18.1 22.8 32.8 22.0 0.0 53.8 30.5 12.1 9.8 37.0 215.9 3.1 29.0 30.7 16.8 213.5 114.7 23.3 5.3 28.5 42.3 6.9 25.3 39.2 11.4 27.0 16.0 0.0 60.3 63.7 28.5 23.0 48.6 237.0 5.0 27.6 19.6 108.7 22.4 0.8 39.1 119.6 235.3 94.7 22.8 3.4 85.3 47.1 20.1 8.2 11.9 0.0 6.6 100.8 32.2 2.7 33.6 36.7 50.4 17.6 42.5 62.8 92.7 27.3 CDKN2AIPNL "C2AIL, MGC13017" ENSG00000237190 "CDKN2A interacting protein N-terminal like" Q96HQ2 5 134402065-134411881 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 81.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043966 Approved NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "HPA043966: AB_2678750" "unprognostic (7.58e-2)" "unprognostic (1.24e-1)" "unprognostic (7.33e-3)" "unprognostic (4.54e-3)" "unprognostic (2.56e-1)" "unprognostic (7.38e-2)" "unprognostic (1.03e-3)" "unprognostic (1.08e-1)" "unprognostic (4.76e-1)" "unprognostic (3.55e-2)" "unprognostic (1.35e-3)" "unprognostic (1.00e-1)" "unprognostic (5.84e-3)" "unprognostic (1.30e-1)" "unprognostic (1.62e-1)" "unprognostic (1.59e-1)" "unprognostic (8.79e-2)" 15.5 23.7 25.8 11.0 27.2 17.0 14.2 25.8 30.6 11.4 20.0 16.8 19.2 12.3 15.6 12.8 11.7 9.4 35.5 27.8 28.2 20.9 17.3 10.8 16.6 29.4 25.2 12.7 33.0 19.7 19.3 11.4 29.3 13.9 13.9 24.3 18.3 10.4 81.7 14.9 17.4 10.0 25.2 14.5 19.2 19.7 27.8 19.0 21.0 42.9 15.8 15.7 11.8 25.7 71.2 42.1 44.1 95.4 22.5 30.5 46.1 37.8 21.5 47.2 52.1 73.1 41.8 47.1 50.3 25.5 68.0 23.0 59.2 93.0 50.8 67.4 89.5 44.1 45.0 43.8 37.8 30.8 25.8 24.5 44.6 59.4 46.3 37.9 49.7 75.3 42.4 54.3 35.4 41.2 50.6 58.2 77.6 37.3 53.1 43.0 46.5 58.3 44.2 23.9 58.7 64.5 50.8 14.1 69.1 49.3 63.1 55.2 33.4 55.8 37.0 44.7 53.7 38.8 69.2 50.2 65.2 53.7 58.7 10.5 16.7 12.4 17.8 18.2 22.7 30.1 22.9 17.7 20.2 28.1 21.7 21.6 4.6 17.8 20.9 24.2 25.3 15.2 25.8 27.2 25.8 30.6 27.8 28.2 29.4 25.2 29.3 25.2 27.8 25.7 21.3 3.2 15.6 3.3 23.7 13.5 16.6 33.6 13.6 21.9 23.9 20.2 50.7 18.6 14.1 9.2 14.6 37.8 17.4 15.3 58.7 28.6 22.0 17.3 16.4 22.7 31.0 34.5 8.8 36.3 40.4 17.2 8.6 12.3 15.2 34.7 22.1 12.6 24.6 15.2 9.1 21.2 36.7 19.4 15.4 46.1 22.1 14.2 23.2 3.7 31.3 30.1 15.5 3.5 7.0 26.0 17.4 19.9 22.6 11.9 30.0 45.4 10.7 26.8 19.7 15.6 22.4 35.1 32.3 18.6 15.3 20.2 17.6 23.5 22.9 14.4 CDKN2B "CDK4I, INK4B, MTS2, P15, p15INK4b, TP15" ENSG00000147883 "Cyclin dependent kinase inhibitor 2B" P42772 9 22002903-22009305 "Human disease related genes, Predicted intracellular proteins" "Cell cycle" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 36.2;intestine: 30.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 240.7;Pancreatic endocrine cells: 164.5;Proximal enterocytes: 139.0;Squamous epithelial cells: 142.0;Urothelial cells: 241.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "classical monocyte: 3.3;intermediate monocyte: 3.3;non-classical monocyte: 9.0" "Lineage enriched" "Detected in single" 17 "monocytes: 9.0" "Cell line enhanced" "Detected in many" "ASC TERT1: 38.1;HaCaT: 35.0;HeLa: 33.9;hTERT-RPE1: 60.1;SiHa: 48.0;SK-MEL-30: 35.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB000349, HPA052838, HPA063327" Uncertain Approved Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "CAB000349: , HPA052838: , HPA063327: AB_2684987" "unprognostic (2.30e-1)" "unprognostic (9.23e-2)" "unprognostic (2.19e-1)" "prognostic unfavorable (4.47e-6)" "unprognostic (2.10e-1)" "unprognostic (7.40e-2)" "prognostic unfavorable (1.49e-4)" "unprognostic (2.01e-1)" "unprognostic (3.03e-2)" "unprognostic (3.19e-2)" "unprognostic (1.13e-1)" "unprognostic (1.36e-1)" "prognostic unfavorable (1.03e-4)" "unprognostic (9.14e-3)" "unprognostic (1.29e-1)" "unprognostic (2.72e-1)" "unprognostic (7.28e-2)" 18.7 1.9 2.0 2.9 1.8 0.4 8.6 1.1 1.9 9.6 9.1 22.4 21.7 3.8 0.6 36.2 1.7 2.4 1.0 1.6 2.2 1.2 1.2 12.6 1.1 2.7 1.5 0.9 1.2 3.3 3.5 2.3 2.3 3.6 19.7 2.8 6.7 4.7 7.2 12.9 30.9 2.1 1.7 4.6 6.0 5.3 2.4 0.8 1.1 1.1 8.1 7.9 20.2 2.4 0.0 0.0 0.3 2.1 28.2 38.1 0.7 1.8 0.0 4.6 12.6 3.6 10.3 0.0 3.4 2.3 0.0 35.0 0.8 6.9 5.5 2.6 9.7 0.0 33.9 1.5 14.4 1.1 6.1 8.1 0.0 6.5 25.8 60.1 4.4 0.0 0.0 17.1 7.3 2.8 0.0 0.1 1.7 1.7 19.5 0.0 2.4 0.7 10.0 0.0 5.4 0.1 48.0 11.5 35.7 25.8 3.0 0.0 14.8 0.0 0.7 0.1 0.0 13.5 8.4 0.1 0.0 1.0 0.0 0.0 3.3 0.0 0.1 3.3 0.0 0.0 0.2 0.3 0.5 0.0 0.0 0.1 0.0 0.0 9.0 0.0 0.0 1.0 2.0 1.8 1.1 1.9 1.6 2.2 2.7 1.5 2.3 1.7 2.4 2.4 3.5 67.3 6.7 0.3 2.9 5.4 27.0 40.5 5.7 3.2 6.4 9.8 3.1 1.5 37.5 5.5 0.0 1.2 3.2 240.7 0.0 57.7 11.3 31.8 7.5 4.1 7.7 0.0 0.1 38.2 0.8 11.5 30.5 37.2 0.0 0.4 1.8 0.1 1.2 0.0 0.5 31.6 14.2 17.6 3.8 2.7 0.6 5.6 3.6 2.8 3.2 4.8 0.0 1.0 0.5 164.5 75.6 1.2 2.1 65.3 139.0 0.1 17.9 7.2 0.0 2.7 8.9 13.8 3.5 142.0 24.2 3.1 2.9 1.2 23.3 241.6 CDS1 ENSG00000163624 "CDP-diacylglycerol synthase 1" Q92903 4 84583127-84651334 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 129.8;Respiratory ciliated cells: 210.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 46.1;hTCEpi: 56.9;OE19: 45.5;SK-BR-3: 62.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036187, HPA064546" Enhanced NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 49: Ciliated cells - Cilium organization" "HPA036187: AB_10601797, HPA064546: AB_2732714" "unprognostic (8.74e-2)" "unprognostic (7.11e-2)" "prognostic favorable (5.22e-4)" "unprognostic (2.73e-3)" "unprognostic (1.45e-2)" "unprognostic (1.73e-1)" "unprognostic (3.10e-3)" "unprognostic (3.11e-1)" "unprognostic (2.62e-1)" "unprognostic (1.35e-1)" "unprognostic (1.16e-1)" "unprognostic (6.67e-2)" "prognostic favorable (0.00e+0)" "unprognostic (2.23e-1)" "unprognostic (1.78e-1)" "unprognostic (3.06e-1)" "unprognostic (2.06e-1)" 1.0 6.1 8.8 1.5 9.5 0.6 10.2 11.1 17.8 6.3 19.0 20.0 40.2 3.0 29.0 20.1 32.2 8.0 0.5 8.9 11.6 14.9 0.5 10.7 0.6 15.9 11.2 5.2 4.7 28.3 4.8 7.2 16.6 9.4 21.3 22.4 12.5 4.7 0.1 15.4 34.4 1.2 9.9 1.6 18.4 7.4 14.7 3.5 30.4 0.1 5.1 6.7 9.2 8.2 26.5 0.6 1.5 0.3 0.1 0.0 26.5 0.0 0.4 0.6 0.5 11.2 46.1 0.0 2.0 0.0 5.4 27.2 8.5 23.2 0.3 1.8 12.6 0.0 3.8 2.7 0.0 0.8 1.8 0.2 56.9 0.0 8.2 1.0 0.0 1.5 0.1 0.0 0.1 18.8 0.2 0.1 3.8 45.5 1.8 0.1 0.0 5.7 12.7 20.0 10.6 0.2 2.9 62.1 0.1 4.9 19.0 0.5 0.0 0.0 1.4 2.8 3.5 0.0 0.0 0.0 2.6 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.8 9.5 11.1 17.8 8.9 11.6 15.9 11.2 16.6 9.9 14.7 8.2 0.8 16.0 42.3 33.3 0.4 29.1 27.7 26.4 26.7 16.7 26.6 13.6 1.4 24.3 39.5 40.5 10.4 60.0 0.4 63.0 3.9 26.4 12.1 129.8 3.8 3.3 22.3 0.0 43.1 22.8 12.1 3.5 41.3 45.2 0.0 15.4 1.4 0.7 12.7 21.9 64.6 53.9 48.8 3.5 13.9 4.5 0.6 3.5 0.0 9.4 1.2 29.0 0.0 3.5 2.4 40.8 30.4 0.4 0.1 30.8 80.0 15.9 210.7 32.0 0.0 1.2 4.3 13.1 6.6 41.1 54.1 57.3 1.6 4.8 51.6 38.3 CDS2 ENSG00000101290 "CDP-diacylglycerol synthase 2" O95674 20 5126879-5197887 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/84: 160.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019698 Approved Approved "Endoplasmic reticulum" No No "Cluster 38: Basophils - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 16: U-266 - Nucleosome" "Cluster 48: Smooth muscle cells - ECM organization" "Endoplasmic reticulum" "HPA019698: AB_1846464" "unprognostic (4.59e-2)" "unprognostic (1.98e-1)" "unprognostic (2.39e-1)" "unprognostic (3.37e-2)" "unprognostic (1.15e-1)" "unprognostic (1.99e-1)" "unprognostic (1.44e-1)" "unprognostic (3.22e-1)" "unprognostic (1.71e-2)" "unprognostic (1.48e-1)" "unprognostic (3.35e-3)" "unprognostic (1.65e-1)" "prognostic favorable (3.53e-9)" "unprognostic (8.89e-2)" "unprognostic (3.53e-1)" "unprognostic (1.38e-1)" "unprognostic (2.44e-1)" 14.3 13.8 30.0 9.1 32.4 13.0 10.6 22.9 28.6 10.5 2.1 13.0 5.2 11.5 8.2 9.2 10.7 8.9 24.8 30.3 34.6 14.6 12.8 13.4 8.8 27.2 36.1 9.3 6.5 17.3 14.4 9.9 37.4 13.4 10.7 31.5 7.6 16.7 9.7 5.9 10.1 18.0 18.8 9.4 10.6 11.7 42.5 13.3 12.5 12.7 12.6 10.8 7.7 21.7 25.4 27.4 28.1 13.7 16.4 14.9 11.7 13.9 28.5 22.7 32.2 17.8 23.8 19.8 6.8 26.4 41.1 36.5 23.1 29.5 23.9 18.4 6.8 23.5 7.9 27.0 15.3 13.9 8.1 12.8 16.1 29.8 11.5 20.3 30.7 26.5 11.6 23.9 21.4 4.6 30.1 5.7 12.1 12.4 7.6 25.0 22.5 9.4 14.5 25.0 11.4 15.5 15.3 26.2 34.6 33.8 16.4 6.7 25.4 15.6 11.6 14.1 14.0 20.8 160.2 15.9 7.4 11.7 8.1 55.3 17.3 21.2 15.2 14.7 16.6 12.1 15.6 17.3 13.8 11.4 12.0 11.8 49.7 12.0 13.4 10.9 19.5 23.7 30.0 32.4 22.9 28.6 30.3 34.6 27.2 36.1 37.4 18.8 42.5 21.7 43.3 19.2 15.7 36.9 36.2 17.6 30.3 33.0 14.2 60.1 17.7 14.4 55.2 18.6 19.6 33.1 95.9 22.2 29.6 15.3 5.9 33.1 71.6 20.1 14.0 42.3 10.7 14.9 39.3 22.7 40.0 17.9 15.3 21.5 21.0 20.5 27.8 21.7 60.8 43.7 52.0 12.4 12.2 36.6 26.1 33.3 16.1 31.5 32.0 21.5 38.7 21.9 28.8 28.6 56.1 31.7 20.3 24.8 48.9 23.1 15.7 13.2 23.5 65.5 19.7 19.7 52.1 26.8 34.7 14.8 15.3 16.3 36.7 13.0 13.1 29.1 CEMIP "HYBID, IR2155535, KIAA1199, TMEM2L" ENSG00000103888 "Cell migration inducing hyaluronidase 1" Q8WUJ3 15 80779343-80951776 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 25.3;endometrium 1: 31.9" "Group enriched" "Detected in some" 5 "Excitatory neurons: 62.5;Inhibitory neurons: 40.0;Microglial cells: 101.2" "Cancer enhanced" "Detected in all" "colorectal cancer: 21.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 204.1;BJ hTERT+: 321.8;fHDF/TERT166: 258.7;HSkMC: 169.3;hTERT-RPE1: 187.6;U-138 MG: 90.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted in other tissues" NA NA 1700000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (1.14e-3)" "unprognostic (6.80e-2)" "unprognostic (5.95e-2)" "unprognostic (3.15e-3)" "unprognostic (3.49e-3)" "unprognostic (6.80e-2)" "unprognostic (5.47e-2)" "unprognostic (1.22e-1)" "unprognostic (7.49e-2)" "unprognostic (1.53e-1)" "unprognostic (7.24e-2)" "unprognostic (1.36e-1)" "unprognostic (5.27e-10)" "unprognostic (1.82e-2)" "unprognostic (1.93e-1)" "unprognostic (1.34e-1)" "prognostic unfavorable (2.65e-4)" 5.7 1.7 1.6 11.2 8.8 1.5 0.8 5.5 11.1 13.3 25.3 1.3 0.8 31.9 6.9 6.4 6.2 2.1 1.9 2.4 3.5 0.9 0.8 15.0 9.5 3.0 1.7 4.7 1.0 1.5 8.0 2.6 2.4 2.0 1.8 4.1 1.9 1.6 0.4 5.9 1.6 0.6 5.1 1.8 0.9 2.9 4.4 0.3 3.9 0.0 4.7 14.0 2.6 3.1 0.7 7.7 1.5 1.1 0.5 2.8 0.9 204.1 321.8 5.4 4.1 2.4 1.0 1.0 0.6 258.7 0.9 4.9 0.0 0.7 1.1 0.6 1.9 0.7 1.3 17.1 1.9 0.5 1.0 169.3 0.2 39.6 0.2 187.6 0.0 1.0 1.0 0.8 4.8 4.7 0.7 0.5 1.0 68.9 9.2 1.2 0.3 0.9 0.0 3.5 12.7 0.4 3.5 0.5 17.7 2.7 1.0 0.4 1.0 90.6 0.9 6.8 3.5 0.8 0.7 1.2 9.6 1.8 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 1.6 8.8 5.5 11.1 2.4 3.5 3.0 1.7 2.4 5.1 4.4 3.1 0.1 0.0 1.5 2.9 0.1 0.0 0.3 0.0 11.4 2.9 0.0 0.1 1.2 0.0 4.3 0.0 6.2 0.2 0.0 1.1 0.0 0.1 1.0 0.7 4.3 1.6 4.8 0.0 62.5 0.4 0.2 4.3 0.0 7.0 1.3 0.1 0.4 0.0 0.4 3.3 40.0 0.5 0.0 0.0 0.0 0.6 0.3 0.9 0.0 101.2 0.0 0.4 0.0 6.6 8.2 0.7 0.1 0.0 0.1 2.7 0.0 0.1 0.0 3.0 0.0 0.4 0.8 0.2 0.7 1.0 0.0 0.3 0.1 0.1 0.8 0.9 CENPE "KIF10, PPP1R61" ENSG00000138778 "Centromere protein E" Q02224 4 103105349-103198445 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Developmental protein, Motor protein" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 10.0;lymphoid tissue: 9.2" "Cell type enhanced" "Detected in many" "Erythroid cells: 75.1;Extravillous trophoblasts: 28.4;Granulosa cells: 32.0;Spermatocytes: 75.3;Spermatogonia: 51.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "basophil: 2.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA011110, HPA042294" Enhanced Enhanced "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes Yes "Cluster 46: Basophils - DNA binding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Microtubules "Cytokinetic bridge, Mitotic spindle" "HPA011110: , HPA042294: AB_10797386" "unprognostic (1.62e-1)" "unprognostic (1.03e-1)" "unprognostic (5.64e-3)" "unprognostic (2.55e-2)" "unprognostic (1.65e-1)" "unprognostic (3.44e-2)" "unprognostic (2.40e-8)" "unprognostic (2.49e-3)" "unprognostic (1.59e-2)" "unprognostic (3.38e-1)" "unprognostic (4.88e-5)" "unprognostic (1.15e-2)" "unprognostic (0.00e+0)" "unprognostic (9.95e-3)" "unprognostic (2.49e-1)" "unprognostic (1.05e-1)" "unprognostic (2.37e-1)" 0.4 0.2 0.4 2.7 0.4 10.0 0.6 0.3 0.5 0.4 0.4 1.8 1.5 0.6 0.0 2.0 0.2 0.8 0.2 0.3 0.6 0.2 0.5 0.8 5.6 0.5 0.5 0.1 0.1 0.3 0.0 1.4 0.9 0.3 2.0 0.4 0.3 0.2 0.0 2.0 1.7 1.1 0.3 1.2 1.1 4.1 0.5 9.2 0.2 0.6 4.9 0.8 0.6 0.5 42.6 11.8 42.2 20.5 2.7 6.2 8.4 36.7 18.2 26.9 17.9 19.6 22.2 28.6 9.2 13.7 19.2 18.2 30.3 15.1 42.2 35.9 11.3 33.5 26.8 13.6 0.4 39.9 18.6 1.8 1.1 21.7 18.0 6.0 22.9 25.2 34.4 32.5 34.8 15.6 31.5 18.9 13.8 17.0 17.9 20.9 38.5 9.3 8.0 8.4 19.3 11.5 32.9 22.9 9.0 16.0 12.9 13.9 26.1 25.8 27.2 27.2 38.6 15.9 28.6 28.8 14.2 21.7 27.8 2.9 0.0 0.3 0.0 0.2 0.0 0.2 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.3 1.5 0.2 0.6 0.0 0.4 0.4 0.3 0.5 0.3 0.6 0.5 0.5 0.9 0.3 0.5 0.5 1.4 3.2 2.2 1.0 6.6 3.6 1.5 2.9 0.0 7.6 1.8 2.7 1.9 0.0 1.3 0.0 8.4 12.7 3.9 4.7 0.0 0.5 7.7 3.5 5.7 4.2 1.2 75.1 2.0 0.0 28.4 6.5 4.6 6.9 7.0 32.0 4.2 0.9 14.1 0.0 1.9 4.3 4.1 10.4 5.7 3.5 0.9 9.6 0.0 0.0 6.0 1.3 2.1 0.5 3.1 1.8 1.4 2.6 16.0 1.4 0.8 0.3 0.3 2.6 0.0 5.7 7.4 75.3 51.0 8.3 2.8 3.6 6.6 7.0 11.6 1.9 CENPF hcp-1 ENSG00000117724 "Centromere protein F" P49454 1 214603195-214664571 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, DNA synthesis, Mitosis, Myogenesis" "Developmental protein" "Cancer-related genes, Ciliopathy, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 28.8;lymphoid tissue: 33.0" "Cell type enhanced" "Detected in many" "Early spermatids: 84.4;Erythroid cells: 268.7;Extravillous trophoblasts: 78.8;Granulosa cells: 165.8;Spermatocytes: 107.5;Spermatogonia: 107.1" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" "HPA052382, HPA064308, CAB070134" Enhanced Supported Nucleoplasm Yes Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB070134: AB_2229328, HPA052382: AB_2681808, HPA064308: AB_2732711" "unprognostic (2.80e-1)" "unprognostic (2.16e-1)" "unprognostic (2.65e-1)" "unprognostic (5.30e-2)" "unprognostic (1.73e-1)" "unprognostic (2.40e-2)" "prognostic unfavorable (2.29e-5)" "unprognostic (1.13e-2)" "unprognostic (2.58e-3)" "unprognostic (1.11e-1)" "prognostic unfavorable (1.39e-4)" "unprognostic (1.58e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.92e-2)" "unprognostic (1.71e-1)" "unprognostic (1.89e-2)" "unprognostic (4.12e-1)" 0.8 1.1 0.1 4.4 0.1 28.8 1.8 0.0 0.3 1.3 0.5 5.8 6.1 1.8 0.1 8.6 0.6 0.7 0.4 0.3 0.0 0.4 0.9 0.9 8.5 0.3 0.5 0.7 0.3 0.2 0.1 3.1 0.3 0.5 5.7 1.0 1.4 0.1 0.2 6.2 4.3 2.5 0.2 2.4 2.6 10.5 0.5 33.0 0.4 0.6 10.0 1.4 2.6 0.3 123.7 68.4 144.3 75.8 5.4 7.2 56.3 74.6 30.3 43.9 42.8 54.6 74.1 116.3 43.1 41.7 39.8 74.7 89.9 49.2 74.1 102.6 56.6 96.0 111.4 78.6 0.8 137.0 50.5 2.7 3.8 63.3 72.3 12.7 46.9 52.6 88.4 68.0 79.4 47.0 81.5 54.3 127.9 36.8 30.0 85.7 203.7 38.6 43.2 30.3 67.4 91.2 100.7 66.2 38.9 76.2 79.1 51.9 61.7 78.9 92.2 66.2 155.9 51.6 60.7 108.7 34.4 96.7 71.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.3 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.3 0.3 0.0 0.3 0.5 0.3 0.2 0.5 0.3 3.0 0.0 3.1 0.0 11.5 9.3 2.8 11.2 3.4 4.7 10.0 6.7 1.9 1.5 9.9 0.0 0.0 53.3 10.8 19.1 0.0 2.0 84.4 30.1 19.3 12.4 0.0 268.7 1.3 0.4 78.8 19.0 32.1 25.2 1.3 165.8 8.9 2.6 32.2 1.7 0.8 20.1 14.2 16.6 6.6 19.8 1.2 16.2 1.8 1.0 0.7 1.4 5.2 0.0 0.1 0.5 1.1 3.0 25.9 2.3 2.1 0.1 16.7 3.1 0.0 8.3 23.9 107.5 107.1 44.6 5.5 5.1 23.3 11.7 41.3 3.7 CENPH ENSG00000153044 "Centromere protein H" Q9H3R5 5 69189574-69210357 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 33.8;testis: 29.7" "Cell type enhanced" "Detected in many" "Erythroid cells: 74.5;Spermatocytes: 222.7;Spermatogonia: 222.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" HPA036494 Approved Supported "Nucleoplasm,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 15: NK-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nucleoli rim" "Mitotic chromosome" "HPA036494: AB_10673354" "unprognostic (1.49e-1)" "prognostic favorable (6.86e-4)" "unprognostic (1.73e-2)" "unprognostic (3.16e-2)" "unprognostic (2.32e-1)" "unprognostic (3.87e-2)" "prognostic unfavorable (5.22e-5)" "unprognostic (6.14e-3)" "unprognostic (6.85e-2)" "prognostic favorable (2.50e-4)" "unprognostic (4.21e-2)" "unprognostic (8.80e-2)" "prognostic unfavorable (5.11e-15)" "unprognostic (1.17e-1)" "unprognostic (3.94e-1)" "unprognostic (2.58e-1)" "unprognostic (2.20e-1)" 4.2 2.0 1.4 7.5 1.7 33.8 7.7 1.7 2.0 3.9 1.0 7.4 6.5 4.5 2.1 7.5 4.0 1.8 4.0 1.5 1.6 1.6 3.6 2.8 17.7 1.6 1.5 3.9 1.5 2.0 1.4 5.2 1.6 3.3 8.1 2.5 2.9 2.3 4.0 9.2 5.9 3.7 1.4 5.2 3.7 29.7 1.6 18.5 2.5 4.0 18.8 3.8 4.4 2.2 64.6 19.4 88.6 70.2 5.8 18.3 48.0 31.2 32.6 66.9 71.8 26.5 79.6 138.9 36.6 18.1 39.1 47.0 59.0 70.4 85.1 42.7 41.4 32.7 32.5 26.4 2.0 47.1 32.1 7.1 14.6 43.6 47.7 18.9 23.2 73.7 58.7 53.3 52.2 35.6 152.4 67.3 78.1 20.7 17.0 93.2 118.2 108.2 21.1 22.9 61.6 81.9 34.6 22.8 27.5 47.7 31.9 31.4 11.4 33.4 56.1 44.5 78.7 65.5 106.3 111.8 51.1 94.2 64.7 1.0 2.0 3.0 4.7 3.5 7.7 13.3 7.9 6.0 3.1 14.1 9.9 8.6 0.4 8.6 4.2 6.7 9.7 4.8 1.4 1.7 1.7 2.0 1.5 1.6 1.6 1.5 1.6 1.4 1.6 2.2 4.8 0.0 2.6 1.0 18.3 36.7 17.7 17.4 9.6 3.4 10.8 11.7 3.3 4.3 7.1 0.0 0.0 37.4 9.2 5.1 0.0 12.3 26.5 5.5 5.1 6.9 1.2 74.5 1.3 9.1 49.0 7.4 2.6 4.8 5.1 22.4 4.6 1.1 17.0 0.0 1.1 9.5 12.2 7.5 18.2 22.5 3.7 6.3 8.8 1.0 4.3 7.3 6.2 1.0 0.9 7.0 2.5 4.9 14.4 6.9 1.4 3.4 10.8 3.5 19.7 6.4 9.3 222.7 222.8 12.1 19.2 10.0 12.0 6.9 15.9 15.2 CENPK "CENP-K, FKSG14, SOLT" ENSG00000123219 "Centromere protein K" Q9BS16 5 65517766-65563168 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 24.6;lymphoid tissue: 22.2" "Cell type enhanced" "Detected in many" "Erythroid cells: 50.9;Extravillous trophoblasts: 50.6;Spermatocytes: 101.3;Spermatogonia: 75.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA Yes "Cluster 20: T-cells - T-cell receptor" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "unprognostic (4.04e-2)" "unprognostic (1.77e-2)" "unprognostic (1.57e-2)" "unprognostic (5.04e-2)" "unprognostic (1.85e-1)" "unprognostic (3.04e-3)" "unprognostic (3.69e-4)" "unprognostic (3.22e-3)" "unprognostic (9.59e-3)" "unprognostic (3.32e-2)" "unprognostic (3.16e-3)" "unprognostic (1.98e-2)" "unprognostic (6.33e-15)" "unprognostic (2.22e-1)" "unprognostic (2.97e-1)" "unprognostic (8.42e-2)" "unprognostic (3.11e-1)" 1.1 0.9 0.6 10.6 0.7 24.6 3.8 1.0 0.8 1.2 1.6 9.0 8.3 1.9 0.9 5.6 2.3 1.9 0.5 0.5 0.6 0.8 1.9 2.0 14.6 1.0 0.7 0.8 0.6 1.0 0.3 5.5 1.1 1.3 11.9 0.7 1.4 0.7 0.2 8.6 8.6 3.4 0.7 4.5 5.5 13.4 1.0 22.2 1.2 0.5 12.4 2.6 2.4 1.4 65.3 41.4 85.6 29.5 4.4 12.0 40.8 69.8 26.5 58.7 73.6 35.1 97.2 39.3 25.2 23.6 59.5 39.7 33.3 35.4 92.7 45.2 28.5 42.1 50.7 33.8 1.7 50.1 36.8 5.6 5.0 56.9 27.3 10.6 56.4 42.2 31.8 57.7 59.1 21.5 85.4 56.2 41.1 18.5 17.1 52.5 81.9 43.8 38.8 34.4 35.8 28.9 53.7 22.1 28.7 31.8 40.0 36.9 20.3 44.9 46.5 31.1 82.2 30.0 51.9 83.0 41.9 74.0 49.9 3.7 0.7 2.3 9.9 1.0 14.8 4.0 21.1 12.5 1.7 7.0 28.5 20.2 1.7 10.2 1.1 1.6 23.2 10.0 0.6 0.7 1.0 0.8 0.5 0.6 1.0 0.7 1.1 0.7 1.0 1.4 2.7 0.0 3.4 0.3 11.7 23.6 8.5 14.0 4.6 1.6 6.0 7.9 0.9 0.0 8.1 0.0 0.0 28.8 18.7 5.8 1.9 3.1 27.6 25.5 4.5 5.7 0.0 50.9 3.1 1.0 50.6 6.3 9.2 7.2 2.5 22.7 3.9 1.1 22.4 0.0 2.3 14.7 8.2 1.9 12.0 17.4 1.5 5.7 1.8 11.2 1.8 0.6 7.2 2.0 1.4 2.3 2.1 1.5 14.1 2.2 1.1 0.3 7.1 1.1 0.0 2.3 9.1 101.3 75.1 17.0 8.1 6.7 20.7 3.9 15.8 11.4 CENPN "BM039, C16orf60, FLJ13607, FLJ22660" ENSG00000166451 "Centromere protein N" Q96H22 16 81006552-81033114 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 37.4" "Cell type enhanced" "Detected in many" "Erythroid cells: 64.2;Extravillous trophoblasts: 91.1;Spermatocytes: 52.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA052870 Supported Nucleoplasm NA NA "Cluster 24: B-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA052870: AB_2681978" "unprognostic (1.23e-2)" "unprognostic (2.40e-1)" "unprognostic (1.15e-1)" "unprognostic (1.76e-2)" "unprognostic (2.15e-1)" "unprognostic (1.76e-2)" "unprognostic (3.69e-3)" "prognostic unfavorable (6.49e-4)" "unprognostic (1.90e-1)" "unprognostic (2.36e-3)" "prognostic unfavorable (1.46e-5)" "unprognostic (3.02e-2)" "prognostic unfavorable (4.86e-4)" "unprognostic (2.34e-2)" "unprognostic (7.42e-2)" "unprognostic (1.41e-2)" "unprognostic (7.99e-2)" 5.1 5.0 3.2 7.9 4.0 37.4 3.6 3.1 4.9 2.8 2.1 8.0 7.8 2.3 3.1 7.5 1.6 3.1 5.7 3.3 3.1 5.4 9.0 3.3 11.0 3.8 4.0 1.5 5.2 8.6 1.6 8.9 3.4 18.7 7.6 1.4 2.5 2.7 4.5 3.8 6.4 6.4 2.7 4.3 5.2 11.2 3.9 18.1 2.8 2.6 12.0 6.0 2.8 5.8 86.2 81.0 64.9 58.4 16.9 15.1 82.6 97.5 59.3 137.0 59.6 150.8 64.6 48.1 52.4 48.9 62.7 69.9 53.1 61.5 172.9 29.3 47.9 43.0 63.3 100.9 9.6 64.6 80.4 14.0 6.6 123.3 40.8 18.0 62.6 59.1 83.6 65.9 66.9 160.1 78.0 79.6 69.7 37.2 45.4 90.9 64.5 51.3 22.5 58.6 43.2 38.9 140.3 31.8 40.1 38.9 76.2 34.0 38.5 97.7 101.1 66.8 96.8 46.4 112.1 186.8 45.8 43.7 85.8 0.9 1.4 2.4 2.1 2.8 2.0 1.6 2.7 1.5 6.6 5.9 1.3 1.5 1.7 3.6 3.1 2.2 7.9 2.0 3.2 4.0 3.1 4.9 3.3 3.1 3.8 4.0 3.4 2.7 3.9 5.8 2.8 0.0 4.8 1.0 10.2 24.0 15.7 9.6 14.8 1.0 6.0 7.0 4.8 5.7 5.8 3.7 0.0 47.1 10.0 7.4 0.0 5.7 41.8 4.5 3.8 5.8 1.2 64.2 1.9 6.5 91.1 9.7 11.7 6.4 6.3 13.2 6.8 6.3 27.2 0.0 1.1 12.8 12.2 9.7 20.2 40.9 2.8 10.4 7.2 1.0 4.4 0.8 0.0 0.5 6.1 5.1 4.0 3.4 34.7 13.6 5.1 8.8 1.8 0.4 0.0 7.1 10.0 52.3 39.1 32.7 16.3 27.2 10.9 6.3 22.0 16.6 CENPS "APITD1, CENP-S, FAAP16, MHF1" ENSG00000175279 "Centromere protein S" Q8N2Z9 1 10430433-10442808 "Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Mitosis" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 48.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 23.7;Distal tubular cells: 37.2;Proximal tubular cells: 86.1;Respiratory ciliated cells: 27.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 71: Testis - DNA repair" "Cluster 32: U-937 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (2.64e-1)" "prognostic favorable (1.24e-4)" "unprognostic (3.06e-3)" "unprognostic (2.21e-1)" "unprognostic (8.57e-2)" "unprognostic (1.15e-1)" "unprognostic (4.72e-3)" "unprognostic (3.79e-1)" "unprognostic (1.26e-3)" "unprognostic (2.95e-2)" "unprognostic (4.37e-2)" "unprognostic (1.78e-1)" "unprognostic (7.04e-3)" "unprognostic (4.23e-2)" "unprognostic (4.66e-2)" "unprognostic (1.87e-1)" "unprognostic (9.21e-2)" 3.5 8.9 4.7 5.8 4.7 9.1 5.1 4.3 6.4 5.7 5.8 6.8 12.5 4.6 12.3 7.4 9.9 7.6 4.5 4.5 4.5 28.0 8.3 5.1 6.4 4.5 4.5 4.0 7.9 14.5 14.1 4.5 4.3 6.5 7.4 8.8 6.8 4.8 3.6 4.4 9.6 4.2 4.4 3.9 6.3 48.6 4.8 9.5 12.0 3.7 6.4 5.6 4.2 4.4 38.9 25.1 17.4 25.2 13.6 11.3 9.1 21.2 22.4 27.8 21.4 11.5 26.4 29.3 19.3 19.0 15.6 29.5 16.1 24.0 30.0 25.1 17.4 17.2 21.0 24.2 8.7 58.5 21.5 7.0 12.0 29.5 18.3 10.8 16.6 31.2 24.3 24.9 27.0 29.6 27.7 35.1 24.5 33.0 26.6 29.7 19.9 34.5 34.1 13.6 22.0 20.1 23.1 25.4 25.7 14.4 30.9 31.6 9.9 29.2 35.6 26.6 37.1 6.6 16.8 35.5 27.3 65.4 38.5 0.0 1.4 0.8 2.8 2.3 3.8 6.9 4.1 3.1 1.8 6.1 4.5 3.8 0.8 2.1 6.0 5.0 4.5 1.8 4.7 4.7 4.3 6.4 4.5 4.5 4.5 4.5 4.3 4.4 4.8 4.4 2.5 6.4 13.1 0.0 1.1 0.0 0.0 0.0 0.0 0.0 8.6 6.5 0.0 0.0 8.1 5.5 0.0 23.7 2.3 0.0 37.2 16.5 0.0 15.0 3.7 3.6 0.0 0.0 0.0 10.9 12.0 3.5 0.0 3.6 3.8 7.4 0.0 0.0 10.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 10.3 0.0 0.0 0.0 0.0 8.5 0.0 0.0 0.5 0.0 0.0 86.1 27.7 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 6.7 2.0 9.3 0.0 0.0 CENPV "CENP-V, p30, PRR6" ENSG00000166582 "Centromere protein V" Q7Z7K6 17 16342534-16353656 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 100.4;Spermatogonia: 124.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 1.3;memory B-cell: 1.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 106.4;JURKAT: 105.1;NTERA-2: 103.4" "Low region specificity" "Detected in all" "HPA042529, HPA042616" Enhanced Approved Nucleoplasm,Midbody,Cytosol Yes No "Cluster 37: B-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Midbody, Cytosol" "HPA042529: AB_10793882, HPA042616: AB_10794050" "unprognostic (7.64e-2)" "unprognostic (4.41e-2)" "unprognostic (5.92e-2)" "unprognostic (9.66e-3)" "unprognostic (1.16e-1)" "unprognostic (1.32e-1)" "unprognostic (2.24e-1)" "unprognostic (6.47e-2)" "unprognostic (1.21e-1)" "unprognostic (4.00e-2)" "unprognostic (7.73e-3)" "unprognostic (7.93e-2)" "unprognostic (4.09e-3)" "unprognostic (2.58e-1)" "unprognostic (1.89e-2)" "unprognostic (2.54e-2)" "unprognostic (3.60e-3)" 4.0 4.7 11.7 0.6 11.3 5.1 4.6 9.3 11.7 4.4 7.1 9.1 9.8 5.9 3.5 0.5 6.6 1.3 5.6 11.9 13.2 3.4 10.7 2.6 1.2 11.6 11.0 6.2 4.0 3.9 7.0 1.2 10.0 3.1 8.0 4.0 1.5 4.0 21.1 0.8 10.6 4.0 11.6 1.1 13.2 10.3 11.4 17.1 2.4 9.5 1.2 4.2 1.7 11.9 10.7 20.4 106.4 53.4 3.0 2.7 18.2 8.7 8.6 26.5 20.0 20.5 4.7 42.5 17.0 6.5 4.9 3.2 69.3 0.6 16.8 0.0 85.9 10.1 5.0 41.1 29.2 10.1 0.0 7.6 2.8 31.6 18.7 3.0 15.2 105.1 17.4 0.0 8.0 1.8 80.2 34.2 103.4 69.1 0.0 57.1 4.1 4.9 6.1 15.4 56.8 43.9 22.2 0.3 5.2 48.6 0.3 24.8 1.0 0.0 8.6 1.2 0.0 0.0 0.0 24.9 0.0 14.0 0.6 0.0 0.0 1.3 0.1 0.0 0.0 1.4 0.0 0.0 0.2 0.1 0.3 0.3 0.0 0.0 0.0 0.3 0.0 0.0 11.7 11.3 9.3 11.7 11.9 13.2 11.6 11.0 10.0 11.6 11.4 11.9 13.3 0.0 2.7 3.9 13.7 1.0 29.7 0.5 4.6 40.0 22.5 31.6 4.2 30.0 4.4 1.8 4.2 19.6 19.6 43.0 31.3 7.5 16.3 2.6 32.4 5.0 39.4 12.6 18.9 23.3 22.1 9.2 59.1 2.7 5.7 39.7 1.8 50.1 6.0 11.8 21.8 63.0 0.0 1.4 0.7 9.0 8.7 4.6 8.8 3.7 2.0 45.9 13.4 19.6 11.7 17.8 83.9 11.7 10.7 38.0 100.4 43.5 2.5 15.0 26.3 4.2 17.9 81.6 124.2 2.5 2.6 6.4 10.7 8.7 78.9 45.0 CENPVL3 CENPVP3 ENSG00000224109 "Centromere protein V like 3" A0A0U1RRI6 X 51617020-51618912 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 3.8;testis: 3.0" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "NTERA-2: 4.3;PC-3: 14.0;U-2 OS: 9.5" NA NA "Cluster 65: Brain - Ion transport" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "unprognostic (3.07e-2)" "unprognostic (1.48e-1)" 0.0 0.5 1.5 0.0 2.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.0 3.7 0.0 0.0 0.0 0.0 1.0 2.1 0.0 0.0 0.5 0.1 0.0 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.7 0.0 0.0 3.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 14.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 2.1 0.0 1.3 1.0 3.7 1.0 2.1 1.5 0.7 3.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 CEP135 "CEP4, FLJ13621, KIAA0635" ENSG00000174799 "Centrosomal protein 135" Q66GS9 4 55948871-56033361 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Mental retardation, Primary microcephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Early spermatids: 92.3;monocytes: 64.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" "unprognostic (2.75e-1)" "unprognostic (2.71e-2)" "unprognostic (2.48e-2)" "unprognostic (1.06e-2)" "unprognostic (3.63e-1)" "unprognostic (3.42e-2)" "unprognostic (4.65e-3)" "unprognostic (4.78e-3)" "unprognostic (1.83e-3)" "unprognostic (9.89e-3)" "unprognostic (9.50e-2)" "unprognostic (2.27e-1)" "unprognostic (6.02e-9)" "unprognostic (7.55e-2)" "unprognostic (5.54e-2)" "unprognostic (1.95e-1)" "prognostic favorable (6.11e-5)" 2.6 1.6 1.0 7.2 1.3 10.1 2.8 2.1 1.6 3.5 1.9 2.4 3.1 7.6 2.1 2.0 3.3 3.1 1.4 1.2 1.3 4.0 1.3 3.2 10.2 1.7 1.5 5.0 1.7 2.0 1.2 5.9 1.7 2.3 3.2 3.7 1.5 1.6 0.8 3.9 3.3 5.0 1.0 5.7 2.2 6.4 2.0 9.5 2.6 1.3 7.6 2.9 2.2 1.9 8.9 4.8 13.0 12.3 2.6 5.0 5.5 8.6 6.1 7.7 9.0 5.2 9.0 23.7 6.4 3.8 6.0 4.0 13.8 5.2 14.6 6.5 8.4 8.3 7.6 4.9 2.9 15.2 12.6 3.9 4.1 9.9 7.0 3.4 6.5 11.9 15.4 11.0 8.1 5.2 21.3 9.5 8.3 4.4 4.9 15.4 6.1 4.8 5.6 6.4 9.3 9.6 7.7 5.2 6.4 7.8 6.9 9.7 6.5 10.4 17.0 12.5 15.1 5.9 4.4 15.7 5.2 11.8 13.1 9.9 2.1 2.9 3.0 2.8 2.8 3.0 3.9 2.9 1.5 5.6 5.0 3.1 4.3 4.7 3.2 5.6 2.7 1.4 1.0 1.3 2.1 1.6 1.2 1.3 1.7 1.5 1.7 1.0 2.0 1.9 16.3 6.4 12.4 7.8 30.2 9.1 8.2 6.3 7.4 12.6 5.6 6.6 8.5 2.8 9.4 7.3 10.4 20.0 27.3 5.2 3.9 9.4 92.3 23.1 14.6 18.2 5.4 28.2 10.0 5.4 16.3 11.5 3.1 13.0 14.5 38.2 12.5 1.7 10.4 26.9 10.4 5.5 6.1 12.9 11.3 19.4 5.9 19.2 5.4 19.7 64.5 4.3 32.0 8.0 13.9 15.6 6.7 8.2 16.7 5.2 3.0 10.0 17.4 24.5 6.6 16.2 11.2 57.3 38.7 6.8 6.7 9.6 20.0 34.6 5.7 6.3 CEP20 "C16orf63, DKFZp686N1651, FLJ31153, FOPNL, FOR20, PHSECRG2" ENSG00000133393 "Centrosomal protein 20" Q96NB1 16 15865719-15888625 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 11.2;Cardiomyocytes: 28.2;Cytotrophoblasts: 40.4;Extravillous trophoblasts: 27.1;Hofbauer cells: 21.1;Syncytiotrophoblasts: 29.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040599 Supported Supported Centrosome NA NA "Cluster 42: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Centrosome "HPA040599: AB_10794036" "unprognostic (1.10e-1)" "unprognostic (6.29e-2)" "unprognostic (1.16e-3)" "unprognostic (7.16e-2)" "unprognostic (2.45e-1)" "unprognostic (3.77e-2)" "unprognostic (2.23e-2)" "unprognostic (6.01e-2)" "unprognostic (1.72e-1)" "unprognostic (4.92e-1)" "unprognostic (4.35e-2)" "unprognostic (4.78e-1)" "unprognostic (6.14e-2)" "unprognostic (1.21e-1)" "unprognostic (2.48e-2)" "unprognostic (1.71e-1)" "unprognostic (5.45e-3)" 16.5 19.1 7.7 12.7 7.7 14.1 19.1 8.0 16.5 17.2 8.9 14.9 13.0 13.8 1.3 27.6 15.0 13.9 16.9 7.6 9.5 17.4 19.0 13.6 24.2 8.0 8.0 18.7 18.2 8.5 14.3 9.8 8.3 15.5 13.8 10.5 14.2 11.1 45.7 17.4 12.4 8.0 8.1 13.4 15.3 31.5 8.4 15.8 32.5 5.8 15.8 17.5 17.3 8.3 43.1 45.6 16.0 3.6 35.4 43.2 2.5 23.7 26.7 23.6 27.6 24.4 6.1 31.1 30.2 6.9 43.9 33.5 39.8 3.7 49.4 33.2 29.5 4.5 10.2 12.0 29.7 9.3 34.3 4.0 53.4 5.8 36.8 7.4 39.9 70.8 85.0 5.6 7.1 33.2 28.0 34.7 38.8 29.8 3.8 6.9 37.3 4.1 3.6 13.1 14.4 1.4 2.1 30.6 51.1 33.0 4.5 5.5 14.0 4.9 3.7 47.4 83.5 11.3 38.2 53.1 42.6 72.0 36.4 38.1 14.4 7.3 12.6 15.0 16.8 15.9 15.4 15.4 16.1 15.9 16.1 14.7 4.2 19.2 13.3 18.3 16.7 14.7 7.7 7.7 8.0 16.5 7.6 9.5 8.0 8.0 8.3 8.1 8.4 8.3 11.2 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.2 0.0 0.0 0.0 0.0 40.4 8.2 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 27.1 7.8 0.0 0.0 0.0 0.0 0.0 0.0 21.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 29.0 1.3 0.0 0.0 0.0 CEP295NL "DDC8, KIAA1731NL" ENSG00000178404 "CEP295 N-terminal like" Q96MC4 17 78870910-78903217 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "brain: 9.2;testis: 33.6" "Group enriched" "Detected in some" 133 "Early spermatids: 298.6;Late spermatids: 504.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.4;Karpas-707: 1.1;TIME: 1.2;U-2 OS: 1.9" "Not detected" "Not detected" "HPA023609, HPA024619, HPA025717" Uncertain Approved Vesicles NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 78: Testis - Spermatogenesis" "Cluster 9: U-2 OS - Unknown function" "Cluster 34: Spermatids - Unknown function" Vesicles "HPA023609: AB_10610974, HPA024619: AB_10602076, HPA025717: AB_10601900" "unprognostic (1.68e-3)" "unprognostic (4.56e-2)" "unprognostic (2.62e-1)" "unprognostic (5.04e-3)" "unprognostic (1.88e-1)" "unprognostic (1.59e-1)" "unprognostic (1.89e-1)" "unprognostic (9.03e-2)" "unprognostic (8.16e-2)" "unprognostic (9.80e-2)" "unprognostic (2.08e-1)" "unprognostic (3.89e-3)" "unprognostic (3.65e-3)" "unprognostic (1.03e-1)" "unprognostic (2.09e-1)" "unprognostic (1.28e-1)" "unprognostic (6.75e-3)" 0.1 0.1 1.9 0.0 2.2 1.3 0.1 0.5 2.8 0.4 1.6 0.1 0.0 0.2 0.0 0.5 0.2 0.0 0.1 0.9 1.8 0.0 0.0 0.1 0.0 2.8 1.9 0.3 0.1 0.0 0.1 0.1 3.4 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 1.0 0.3 0.1 33.6 3.3 0.0 0.0 0.0 0.0 0.1 0.3 9.2 0.3 0.0 0.0 0.3 0.1 0.2 1.4 0.6 0.0 0.2 0.3 0.1 0.2 0.0 0.4 0.2 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.1 0.1 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.3 0.3 0.0 0.4 1.2 0.5 1.9 0.6 0.2 0.4 0.6 0.0 0.0 0.0 0.6 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 1.9 2.2 0.5 2.8 0.9 1.8 2.8 1.9 3.4 1.0 3.3 9.2 0.7 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 298.6 0.3 1.7 0.5 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.8 0.0 0.5 0.7 0.0 0.6 0.0 0.0 0.0 0.0 0.3 0.0 504.5 2.8 1.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 1.5 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.6 3.0 1.4 0.1 0.0 0.0 0.1 0.7 0.0 0.1 CEP43 "FGFR1OP, FOP" ENSG00000213066 "Centrosomal protein 43" O95684 6 166999317-167094789 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 12.3;Cytotrophoblasts: 14.2;Extravillous trophoblasts: 16.2;Hofbauer cells: 10.3;Syncytiotrophoblasts: 6.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071876 Approved Supported Centrosome NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 45: Intestine - Brush border" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Centrosome "HPA071876: AB_2686467" "unprognostic (9.14e-2)" "unprognostic (2.24e-1)" "unprognostic (3.98e-2)" "unprognostic (2.39e-1)" "unprognostic (1.30e-1)" "unprognostic (1.69e-2)" "unprognostic (9.59e-2)" "unprognostic (1.00e-1)" "unprognostic (6.95e-2)" "unprognostic (8.83e-2)" "unprognostic (1.08e-3)" "unprognostic (4.06e-2)" "prognostic unfavorable (7.32e-4)" "unprognostic (1.29e-2)" "unprognostic (2.49e-1)" "unprognostic (3.15e-1)" "unprognostic (2.09e-3)" 6.9 14.8 8.8 12.6 8.3 16.7 14.3 8.3 10.0 13.5 9.2 12.4 15.9 14.9 16.9 9.0 27.0 11.2 8.9 8.1 8.3 17.4 36.3 7.3 14.8 8.7 11.4 13.0 11.3 10.5 14.1 8.4 9.4 9.4 16.9 25.4 8.8 9.1 8.5 11.6 15.8 10.4 7.7 11.1 11.3 58.4 8.4 15.7 15.5 10.4 17.7 9.2 9.3 9.4 26.1 14.3 35.3 24.2 20.3 15.1 42.7 33.0 21.9 26.4 25.3 53.1 21.6 31.0 18.3 20.2 70.3 24.0 31.4 23.3 49.3 19.5 27.0 21.4 26.7 58.2 10.8 38.4 21.6 8.4 16.8 54.2 25.2 16.4 18.5 34.5 70.9 25.8 34.2 24.0 31.1 55.8 30.2 50.0 10.9 35.3 23.9 25.7 27.8 13.8 26.2 26.2 26.9 28.6 11.7 24.6 23.5 46.7 12.2 26.1 43.7 31.6 42.1 21.8 32.3 31.4 29.4 35.4 32.7 0.4 6.5 23.5 5.1 6.1 7.6 12.1 5.8 4.8 10.7 8.4 3.4 5.5 38.8 6.3 6.7 16.4 11.7 4.9 8.8 8.3 8.3 10.0 8.1 8.3 8.7 11.4 9.4 7.7 8.4 9.4 3.3 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.3 0.0 0.0 0.0 0.0 14.2 3.8 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 16.2 2.1 0.0 0.0 0.0 0.0 0.0 0.0 10.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 6.3 1.3 0.0 0.0 0.0 CEP83 "CCDC41, NPHP18, NY-REN-58" ENSG00000173588 "Centrosomal protein 83" Q9Y592 12 94306449-94459988 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Nephronophthisis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 109.1;Oligodendrocyte precursor cells: 74.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038161 Approved NA NA "Cluster 35: T-regs - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 24: NB-4 - Immune response" "Cluster 49: Ciliated cells - Cilium organization" "HPA038161: AB_10674547" "unprognostic (4.98e-2)" "unprognostic (1.64e-2)" "unprognostic (7.22e-2)" "unprognostic (1.75e-2)" "unprognostic (4.76e-3)" "unprognostic (3.59e-2)" "unprognostic (5.44e-3)" "unprognostic (1.70e-1)" "unprognostic (2.24e-2)" "unprognostic (1.92e-2)" "unprognostic (1.82e-1)" "prognostic unfavorable (4.98e-4)" "prognostic unfavorable (5.00e-10)" "unprognostic (1.29e-2)" "unprognostic (7.83e-2)" "unprognostic (1.12e-2)" "unprognostic (1.95e-2)" 5.5 7.9 4.7 5.3 4.7 6.9 6.8 5.3 5.3 6.0 7.3 5.4 3.9 6.2 6.0 5.1 11.5 3.9 15.2 5.1 4.4 6.1 5.1 5.4 6.0 5.5 6.5 7.8 9.7 5.5 5.1 4.5 5.5 5.2 7.1 5.3 4.1 2.8 5.1 4.9 4.3 4.5 5.6 5.3 5.1 18.6 4.7 5.3 7.1 3.3 5.9 4.6 5.4 6.1 8.2 9.1 15.1 14.2 6.5 8.7 12.9 14.2 4.5 10.1 10.3 11.3 6.7 21.3 3.0 4.3 6.4 11.4 18.3 10.9 15.5 12.5 13.3 12.7 9.2 11.5 6.5 20.9 8.3 5.7 8.9 8.4 25.6 5.9 9.6 17.1 16.6 8.5 10.6 8.3 14.3 34.5 17.2 14.0 16.6 19.4 14.2 21.6 9.1 10.2 15.6 6.5 11.9 13.9 9.9 13.3 9.5 13.0 5.7 11.8 7.3 5.9 11.3 11.1 13.3 19.3 4.9 21.8 11.4 0.6 2.5 1.5 3.8 2.5 3.6 4.7 3.9 3.1 5.7 4.8 4.0 3.6 1.0 4.6 1.2 6.1 5.2 1.5 4.7 4.7 5.3 5.3 5.1 4.4 5.5 6.5 5.5 5.6 4.7 6.1 10.3 16.0 10.7 37.5 17.9 0.0 15.3 0.0 23.9 12.9 12.7 11.7 39.0 1.5 11.8 3.7 14.6 6.8 9.4 8.9 1.9 4.7 55.4 109.1 26.3 8.0 14.9 14.9 51.7 3.5 9.6 13.3 17.3 17.0 26.6 17.8 2.9 5.2 5.7 5.0 45.6 11.9 0.0 4.6 0.0 16.6 10.8 11.6 0.0 46.9 15.1 4.9 11.3 74.4 55.0 3.5 5.2 6.4 17.4 15.0 1.9 5.5 48.1 12.0 0.0 24.9 7.8 45.4 24.0 18.4 0.0 3.3 10.5 15.2 12.5 13.2 CFAP161 "C15orf26, FLJ38615" ENSG00000156206 "Cilia and flagella associated protein 161" Q6P656 15 81007033-81149179 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 34.8;fallopian tube: 15.8" "Cell type enhanced" "Detected in some" "Early spermatids: 18.1;Endometrial ciliated cells: 26.5;Late spermatids: 5.4;Respiratory ciliated cells: 23.3;Spermatocytes: 15.6" "Cancer enriched" "Detected in some" 4 "endometrial cancer: 2.4" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "neutrophil: 1.1" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 5 "HEL: 84.4;K-562: 29.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA076975 Supported NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 36: HEL - Hemostasis" "Cluster 49: Ciliated cells - Cilium organization" "HPA076975: " "unprognostic (1.19e-1)" "unprognostic (1.47e-1)" "unprognostic (6.07e-2)" "prognostic favorable (3.05e-4)" "unprognostic (1.57e-3)" "unprognostic (2.81e-1)" "unprognostic (1.22e-1)" "unprognostic (1.38e-1)" "unprognostic (2.18e-1)" "unprognostic (1.73e-1)" "unprognostic (3.33e-2)" "unprognostic (3.13e-1)" "unprognostic (1.29e-3)" "unprognostic (8.93e-2)" "unprognostic (1.47e-1)" "unprognostic (9.24e-2)" "unprognostic (6.22e-2)" 0.4 0.1 0.8 0.1 1.2 0.6 0.2 4.3 1.1 0.6 34.8 0.1 0.0 0.6 0.6 0.1 15.8 0.2 0.6 1.2 0.6 0.3 0.2 2.7 0.1 2.5 3.5 0.1 0.2 0.3 1.7 1.3 2.0 0.1 0.0 1.3 0.2 0.2 0.2 0.5 0.1 0.2 3.0 0.5 0.2 6.4 1.2 0.0 0.6 0.8 0.2 0.2 0.1 1.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.3 0.2 0.0 0.2 0.2 0.3 0.0 0.0 0.2 0.2 0.0 0.2 0.2 0.3 0.0 84.4 0.2 0.2 0.0 0.0 11.0 0.0 0.0 0.3 1.0 0.0 1.7 0.0 29.2 0.9 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.8 0.0 1.2 0.2 0.2 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.8 0.0 1.4 0.1 0.0 0.2 0.2 0.0 0.1 0.2 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 1.1 0.0 0.0 0.1 0.0 3.4 0.8 1.2 4.3 1.1 1.2 0.6 2.5 3.5 2.0 3.0 1.2 1.0 0.2 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.1 26.5 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 2.8 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 23.3 0.6 0.0 0.0 0.0 15.6 2.4 0.0 0.0 0.0 0.0 0.1 0.0 0.2 CFAP206 "C6orf165, dJ382I10.1, FLJ25974" ENSG00000272514 "Cilia and flagella associated protein 206" Q8IYR0 6 87407972-87464465 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "fallopian tube: 22.3;testis: 59.1" "Group enriched" "Detected in some" 4 "Early spermatids: 300.7;Spermatocytes: 128.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MCF7: 2.3;RPTEC TERT1: 2.6;T-47d: 4.5" "HPA044891, HPA072261" Approved Approved "Nucleoplasm,Cell Junctions" NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 6: T47d - Mammary gland" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm "Cell Junctions" "HPA044891: AB_10960832, HPA072261: AB_2686501" "unprognostic (4.31e-1)" "unprognostic (8.75e-3)" "unprognostic (2.40e-1)" "unprognostic (2.31e-1)" "unprognostic (5.51e-2)" "unprognostic (1.68e-1)" "unprognostic (1.17e-1)" "unprognostic (4.68e-3)" "unprognostic (3.13e-2)" "unprognostic (3.99e-3)" "unprognostic (9.08e-3)" "unprognostic (4.22e-2)" "unprognostic (1.46e-1)" "unprognostic (8.54e-2)" "unprognostic (2.26e-2)" 0.1 0.4 1.0 0.0 0.9 0.0 0.3 0.5 0.9 0.7 4.3 0.0 0.0 0.5 0.6 0.0 22.3 0.1 0.2 0.8 1.4 0.9 0.1 1.5 0.0 2.3 2.6 0.1 0.1 0.7 1.2 0.1 1.6 0.5 0.0 0.5 0.1 0.3 0.0 0.1 0.0 0.1 1.5 0.0 0.0 59.1 1.7 0.0 1.4 0.1 0.0 0.2 0.0 0.9 0.0 0.5 0.2 1.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.1 0.5 0.0 0.0 0.0 1.0 0.4 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.4 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.6 0.6 0.5 0.3 0.2 0.2 0.1 0.0 4.5 0.1 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.9 0.5 0.9 0.8 1.4 2.3 2.6 1.6 1.5 1.7 0.9 0.0 0.0 0.5 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.3 0.3 0.0 0.0 7.4 0.0 0.0 0.1 0.0 0.0 1.9 0.3 300.7 15.8 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 32.5 2.1 0.4 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.1 0.0 1.4 43.7 0.4 0.0 0.0 0.1 128.8 4.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 CFAP298 "C21orf48, C21orf59, CILD26, FBB18, FLJ20467, Kur" ENSG00000159079 "Cilia and flagella associated protein 298" P57076 21 32592079-32612603 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 74.0;Distal tubular cells: 78.2;Ductal cells: 78.5;Endometrial ciliated cells: 272.0;Extravillous trophoblasts: 70.2;Proximal tubular cells: 95.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA018453, HPA019055, HPA028849, CAB034170" Enhanced NA NA "Cluster 24: B-cells - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 49: Ciliated cells - Cilium organization" "CAB034170: AB_1564311, HPA018453: AB_1845700, HPA019055: AB_1845701, HPA028849: AB_10602111" "unprognostic (9.76e-2)" "unprognostic (2.99e-1)" "unprognostic (2.39e-1)" "prognostic favorable (8.90e-4)" "unprognostic (1.55e-1)" "unprognostic (2.80e-2)" "unprognostic (5.05e-3)" "unprognostic (2.50e-1)" "unprognostic (1.81e-1)" "unprognostic (1.81e-3)" "unprognostic (2.07e-2)" "unprognostic (1.49e-1)" "prognostic unfavorable (1.54e-5)" "unprognostic (6.74e-2)" "unprognostic (1.04e-2)" "unprognostic (1.21e-1)" "unprognostic (4.37e-2)" 23.3 29.1 30.3 12.2 30.2 14.0 25.0 35.3 37.0 28.6 38.5 26.5 14.1 27.0 21.2 30.7 35.5 12.0 26.7 30.5 32.0 37.8 29.0 25.1 16.5 29.7 31.2 27.0 36.3 21.3 48.8 12.3 29.6 30.7 13.8 27.6 28.7 10.5 35.2 27.7 22.9 11.4 28.5 23.7 29.3 62.1 32.1 16.0 33.5 11.7 16.5 24.7 26.2 29.5 47.5 26.1 21.4 37.3 11.9 9.2 43.6 23.9 16.1 22.8 15.0 41.9 33.2 36.3 26.4 18.3 24.6 21.9 30.9 29.5 19.5 25.8 53.6 44.5 37.1 57.6 17.2 50.8 31.8 7.8 28.5 37.6 22.8 22.4 16.1 40.6 96.8 18.9 16.4 56.9 49.7 86.8 99.2 63.1 31.6 37.2 24.0 76.5 50.9 26.3 113.8 49.4 35.1 46.5 65.2 21.9 48.6 54.3 24.6 19.6 24.0 32.6 30.4 43.7 66.9 66.0 38.5 68.4 25.3 12.8 13.9 16.2 13.4 15.3 11.1 20.8 17.9 19.0 17.1 24.6 19.9 18.2 1.3 19.9 19.6 23.8 21.4 18.8 30.3 30.2 35.3 37.0 30.5 32.0 29.7 31.2 29.6 28.5 32.1 29.5 38.3 0.0 0.0 0.0 8.7 0.0 0.0 0.0 0.0 0.0 35.8 40.4 0.0 0.0 0.0 46.0 0.0 74.0 28.0 0.0 78.2 78.5 0.0 272.0 34.3 13.2 0.0 0.0 0.0 53.2 70.2 11.1 0.0 45.8 0.0 22.5 0.0 0.0 38.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.7 0.0 0.0 19.7 0.0 0.0 0.0 0.0 50.9 0.0 0.0 4.3 0.0 0.0 95.1 0.0 0.0 0.0 0.0 15.6 0.0 0.0 0.0 0.0 38.0 12.3 28.3 0.0 0.0 CFAP300 "C11orf70, FBB5, MGC13040" ENSG00000137691 "Cilia and flagella associated protein 300" Q9BRQ4 11 102047437-102084554 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 29.2;testis: 30.2" "Cell type enriched" "Detected in some" 4 "Endometrial ciliated cells: 142.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 17.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038585 Enhanced Approved Centrosome NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 49: Ciliated cells - Cilium organization" Centrosome "HPA038585: AB_10795357" "unprognostic (9.70e-2)" "unprognostic (3.18e-1)" "unprognostic (3.02e-1)" "unprognostic (2.20e-3)" "unprognostic (1.05e-1)" "unprognostic (2.04e-1)" "unprognostic (4.16e-2)" "unprognostic (2.62e-1)" "unprognostic (3.03e-2)" "unprognostic (5.00e-2)" "unprognostic (2.66e-2)" "unprognostic (1.18e-1)" "unprognostic (1.77e-6)" "unprognostic (1.76e-2)" "unprognostic (8.68e-3)" "unprognostic (2.94e-2)" "unprognostic (6.73e-3)" 2.7 3.4 2.3 0.4 2.6 0.0 2.6 2.2 2.1 5.4 10.9 1.3 0.8 4.3 10.7 1.8 29.2 3.3 1.3 2.5 3.3 1.7 0.1 3.0 0.9 5.8 6.7 4.1 0.8 2.7 4.0 3.3 5.5 4.0 0.8 1.4 0.8 6.6 0.2 1.3 0.8 2.9 4.7 0.1 1.8 30.2 3.3 0.6 3.6 0.0 0.5 3.0 1.9 4.0 0.1 8.5 8.5 0.0 7.5 17.9 0.2 3.4 8.6 4.6 6.5 0.6 11.1 0.0 2.0 6.7 2.3 2.1 2.1 1.0 3.3 0.0 1.3 0.0 1.3 0.0 5.3 0.0 0.0 7.8 10.5 11.9 8.0 8.9 0.1 0.1 0.0 0.0 10.6 0.0 0.0 0.0 0.0 0.2 3.5 0.0 0.0 0.0 12.6 2.4 9.4 0.0 11.0 0.1 0.0 0.0 9.6 0.0 1.3 1.1 3.5 11.2 2.8 0.1 0.0 0.0 3.7 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.3 2.6 2.2 2.1 2.5 3.3 5.8 6.7 5.5 4.7 3.3 4.0 0.8 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 1.4 3.8 0.0 0.0 0.0 29.5 0.0 7.1 0.1 0.0 1.9 4.0 0.0 142.5 9.8 0.2 0.0 0.0 0.0 0.0 0.5 3.4 0.0 2.1 0.0 2.9 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 1.9 0.2 6.0 0.0 0.0 CFAP43 "bA373N18.2, C10orf79, FLJ22944, FLJ36006, WDR96" ENSG00000197748 "Cilia and flagella associated protein 43" Q8NDM7 10 104129888-104232364 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 34.7;choroid plexus: 80.2;fallopian tube: 48.9;testis: 57.3" "Cell type enhanced" "Detected in many" "Early spermatids: 103.0;Endometrial ciliated cells: 161.0;Late spermatids: 58.4;Respiratory ciliated cells: 231.0;Spermatocytes: 53.7" "Cancer enhanced" "Detected in many" "endometrial cancer: 2.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 4.3;U-266/70: 3.3;U-266/84: 2.9" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "midbrain: 5.9" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (1.20e-2)" "unprognostic (3.05e-2)" "unprognostic (3.61e-2)" "unprognostic (6.46e-3)" "unprognostic (2.03e-1)" "unprognostic (3.35e-2)" "unprognostic (1.07e-1)" "unprognostic (1.78e-1)" "unprognostic (1.56e-1)" "unprognostic (2.80e-1)" "unprognostic (6.88e-3)" "unprognostic (2.18e-1)" "unprognostic (1.76e-1)" "unprognostic (3.41e-1)" "unprognostic (3.35e-2)" "unprognostic (9.11e-4)" "unprognostic (6.67e-2)" 0.3 1.0 8.4 0.2 8.2 0.2 2.5 4.7 4.3 6.0 80.2 0.3 0.4 2.9 7.8 0.2 48.9 0.9 0.2 8.8 10.5 5.9 0.4 8.2 0.3 33.9 34.7 1.8 2.2 3.8 10.1 0.3 23.5 1.5 0.2 10.7 0.9 1.3 0.1 1.0 0.6 0.2 23.8 0.2 0.6 57.3 9.8 0.4 5.3 0.0 0.2 0.2 0.5 14.6 1.7 0.6 0.6 1.1 0.0 0.3 0.1 0.0 0.5 0.3 0.2 0.0 4.3 0.0 0.0 0.0 1.5 0.6 0.1 0.6 0.7 0.2 0.7 0.0 0.3 0.2 0.1 0.0 0.1 0.4 0.5 0.4 0.3 0.9 0.1 0.3 1.2 0.1 0.0 1.1 0.1 0.2 0.1 0.4 0.2 0.1 0.0 0.0 1.5 0.0 0.9 0.9 0.4 0.0 0.8 0.5 0.5 0.0 0.0 0.1 0.3 0.5 0.2 3.3 2.9 0.4 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 8.4 8.2 4.7 4.3 8.8 10.5 33.9 34.7 23.5 23.8 9.8 14.6 0.3 3.2 8.4 16.6 0.1 0.0 0.6 0.0 0.6 0.8 1.9 1.7 0.8 0.0 38.4 1.8 10.4 0.1 0.0 0.0 0.0 1.2 103.0 161.0 2.1 1.0 3.6 0.8 16.6 0.0 0.2 1.2 1.1 3.6 6.3 0.6 0.4 0.1 0.1 0.0 23.5 0.1 0.0 0.0 0.0 58.4 1.5 0.7 0.0 1.9 0.6 1.3 0.0 1.5 6.1 0.2 0.1 2.2 0.2 0.6 0.1 1.2 231.0 8.8 0.0 0.6 0.1 53.7 4.4 0.3 0.0 0.0 0.7 0.4 0.2 0.3 CFAP44 "FLJ11142, WDR52" ENSG00000206530 "Cilia and flagella associated protein 44" Q96MT7 3 113286930-113441610 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 57.4;Endometrial ciliated cells: 40.0;Late spermatids: 61.2;Respiratory ciliated cells: 104.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in some" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "midbrain: 13.7" HPA067258 Uncertain NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 20: HeLa - Mitochondria" "Cluster 49: Ciliated cells - Cilium organization" "HPA067258: AB_2685814" "unprognostic (2.83e-1)" "unprognostic (7.07e-2)" "unprognostic (1.65e-1)" "unprognostic (1.06e-1)" "unprognostic (2.35e-1)" "unprognostic (3.39e-3)" "unprognostic (7.51e-4)" "unprognostic (6.73e-2)" "unprognostic (1.10e-1)" "unprognostic (2.89e-1)" "unprognostic (1.62e-2)" "unprognostic (2.18e-3)" "unprognostic (2.13e-6)" "unprognostic (8.77e-2)" "unprognostic (1.04e-1)" "unprognostic (1.77e-2)" "prognostic favorable (7.09e-6)" 1.6 1.2 1.1 0.9 1.2 0.8 2.5 1.2 1.0 3.7 11.9 2.7 0.7 2.7 2.6 1.6 6.8 1.0 1.7 1.3 1.4 1.9 2.1 2.5 1.3 5.5 4.8 3.3 3.7 1.9 6.3 0.7 2.6 4.2 2.3 8.7 4.9 1.1 1.3 2.3 2.9 0.7 4.4 2.0 3.0 6.1 1.4 1.4 3.2 0.4 1.0 2.4 2.6 2.0 1.1 0.7 1.6 1.4 0.9 1.5 1.5 0.5 0.3 0.3 0.7 0.1 0.6 1.4 0.1 0.2 0.3 1.5 0.9 0.5 0.6 0.3 1.0 0.8 3.4 0.3 0.0 1.5 0.9 0.4 1.4 0.3 0.3 2.0 0.2 1.3 0.2 0.7 0.3 0.7 0.8 1.3 0.5 1.9 1.8 0.8 0.2 0.0 0.8 1.8 1.5 1.4 0.7 0.1 0.8 0.8 1.0 1.1 1.1 0.5 0.8 0.4 0.5 0.9 0.6 0.1 0.7 0.9 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.2 1.2 1.0 1.3 1.4 5.5 4.8 2.6 4.4 1.4 2.0 3.8 9.6 13.7 27.4 2.9 0.0 2.1 0.0 5.7 7.5 6.7 5.2 5.1 2.8 18.6 3.7 20.9 0.9 1.1 3.2 0.0 2.6 57.4 40.0 6.3 4.2 0.0 1.3 34.8 3.0 1.0 5.2 12.2 9.5 11.4 4.3 1.8 3.7 0.5 8.4 14.0 4.7 0.0 0.6 0.0 61.2 6.2 1.8 0.0 20.6 0.9 4.0 3.1 21.1 21.9 2.1 1.9 6.8 2.5 2.2 2.2 1.1 104.9 19.0 0.0 9.7 2.5 23.6 4.9 1.8 0.0 0.8 2.9 6.2 2.7 2.2 CFAP52 "FLJ37528, WDR16, WDRPUH" ENSG00000166596 "Cilia and flagella associated protein 52" Q8N1V2 17 9576627-9643447 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 13.7;choroid plexus: 18.2;fallopian tube: 57.8" "Group enriched" "Detected in some" 6 "Early spermatids: 32.4;Endometrial ciliated cells: 99.6;Respiratory ciliated cells: 81.6;Spermatocytes: 33.9" "Group enriched" "Detected in some" 4 "endometrial cancer: 1.5;glioma: 1.7;lung cancer: 0.6;ovarian cancer: 0.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 1.7;MCF7: 2.1;OE19: 2.7;REH: 1.4;T-47d: 1.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA023247, HPA030635" Enhanced Approved Nucleoplasm,Mitochondria NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 21: OE19 - Mitochondria" "Cluster 49: Ciliated cells - Cilium organization" Mitochondria Nucleoplasm "HPA023247: AB_1858797, HPA030635: " "unprognostic (1.76e-2)" "unprognostic (2.31e-1)" "unprognostic (1.38e-1)" "unprognostic (1.68e-2)" "unprognostic (2.09e-1)" "unprognostic (2.04e-1)" "unprognostic (3.99e-1)" "unprognostic (3.16e-2)" "unprognostic (2.11e-1)" "unprognostic (3.66e-1)" "unprognostic (2.22e-2)" "unprognostic (2.66e-1)" "unprognostic (7.85e-2)" "unprognostic (1.85e-1)" "unprognostic (9.23e-2)" "unprognostic (4.50e-2)" "unprognostic (7.09e-2)" 0.0 0.3 3.8 0.0 4.3 0.0 0.1 2.3 2.9 2.3 18.2 0.1 0.7 1.1 0.1 0.2 57.8 0.2 0.0 4.0 4.1 0.3 0.2 4.4 0.0 10.7 13.7 0.2 0.2 0.3 3.2 0.2 8.4 0.3 0.0 2.4 1.2 0.2 0.0 0.2 0.7 0.0 9.9 0.0 0.1 12.2 3.9 0.3 0.6 0.3 0.0 0.1 0.1 6.6 0.8 0.8 0.0 0.3 0.5 0.4 0.4 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.2 0.0 0.6 0.9 0.0 0.0 0.0 0.2 0.0 0.0 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 2.1 0.0 0.3 0.1 2.7 0.0 1.4 0.0 0.0 0.2 0.4 0.3 0.0 0.3 0.5 0.0 0.3 1.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 4.3 2.3 2.9 4.0 4.1 10.7 13.7 8.4 9.9 3.9 6.6 0.2 0.0 2.3 1.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.1 0.3 0.0 9.9 0.0 6.2 0.8 0.0 0.0 1.9 0.1 32.4 99.6 0.9 0.3 0.0 0.0 9.7 0.2 0.2 0.3 0.0 1.7 0.0 0.1 0.0 0.0 0.1 0.0 1.4 0.0 0.0 0.0 0.0 6.4 1.8 0.0 0.0 1.0 0.0 0.7 0.0 7.1 1.1 0.1 0.0 1.9 0.0 0.3 0.0 0.5 81.6 3.1 0.0 0.1 0.2 33.9 0.8 0.0 0.0 1.0 0.1 0.1 0.0 0.1 CFAP54 "C12orf55, C12orf63, FLJ31514, FLJ44112" ENSG00000188596 "Cilia and flagella associated protein 54" Q96N23 12 96489571-96875555 "Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation, Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 14.7;choroid plexus: 30.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 70.5;Alveolar cells type 2: 80.1;Club cells: 42.7;Endometrial ciliated cells: 65.8;granulocytes: 37.8;Oligodendrocytes: 47.7;Respiratory ciliated cells: 106.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 7.7;TIME: 9.4" "Low region specificity" "Detected in many" HPA039897 Enhanced Approved Microtubules,Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 49: Ciliated cells - Cilium organization" Microtubules Cytosol "HPA039897: AB_10674427" "unprognostic (1.87e-4)" "unprognostic (3.63e-2)" "unprognostic (8.07e-2)" "unprognostic (7.89e-2)" "unprognostic (4.66e-2)" "unprognostic (5.55e-2)" "unprognostic (2.75e-2)" "unprognostic (2.91e-2)" "unprognostic (6.16e-2)" "unprognostic (8.40e-2)" "unprognostic (2.86e-1)" "unprognostic (2.36e-1)" "unprognostic (3.55e-5)" "unprognostic (2.72e-2)" "unprognostic (3.35e-1)" "unprognostic (3.26e-2)" "unprognostic (8.00e-2)" 0.8 0.7 5.6 1.3 8.1 2.7 0.9 9.2 10.3 0.6 30.7 0.7 1.8 1.6 1.6 0.7 5.0 0.8 0.5 7.0 4.6 0.9 0.9 1.4 1.2 14.6 14.7 1.0 0.2 0.6 1.0 0.7 7.3 0.9 1.1 6.2 0.8 0.6 1.3 1.6 1.2 0.6 8.5 1.5 1.0 5.4 7.0 0.5 1.3 0.2 1.1 0.4 0.1 12.4 1.4 0.6 0.8 1.1 0.4 0.6 0.9 0.7 0.2 0.2 0.4 0.6 1.9 1.0 1.6 0.4 0.9 1.0 0.3 0.3 0.3 2.0 0.6 0.9 2.3 0.7 0.1 1.5 1.5 0.2 0.3 1.1 0.5 1.8 7.7 0.9 0.6 3.5 0.8 0.7 1.2 1.5 1.7 0.6 1.0 1.2 1.1 1.3 2.2 1.3 1.6 1.2 0.8 0.7 1.0 0.9 2.1 0.7 9.4 1.7 2.2 1.8 1.5 4.2 2.1 0.6 1.3 0.9 1.3 2.4 0.7 0.6 0.7 0.6 0.5 0.7 0.5 0.6 0.3 1.1 0.6 0.6 1.3 0.7 0.7 0.6 0.4 0.1 5.6 8.1 9.2 10.3 7.0 4.6 14.6 14.7 7.3 8.5 7.0 12.4 2.1 70.5 80.1 27.1 2.6 0.0 0.3 0.0 0.0 3.9 0.3 0.6 1.0 1.5 42.7 0.0 22.9 0.3 2.2 0.0 0.0 0.2 33.2 65.8 2.9 6.8 1.2 1.3 21.9 0.0 0.3 6.4 0.5 1.9 37.8 0.6 0.4 0.0 0.2 0.0 3.9 0.0 0.0 0.8 0.0 15.4 0.3 3.2 0.0 1.9 0.1 8.1 0.0 4.0 47.7 0.3 0.1 0.0 5.0 0.5 0.0 0.3 106.4 7.8 0.0 1.7 0.5 16.8 7.0 0.0 0.0 0.0 4.2 1.9 0.1 0.3 CFAP97 "DKFZp434F1728, hmw, KIAA1430" ENSG00000164323 "Cilia and flagella associated protein 97" Q9P2B7 4 185159665-185209504 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 276.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049446, HPA053335" Uncertain Approved "Nucleoli fibrillar center" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 1: Thyroid gland - Transcription" "Cluster 30: Epithelial cell lines - Translation" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoli fibrillar center" "HPA049446: AB_2680770, HPA053335: AB_2682117" "unprognostic (6.74e-2)" "unprognostic (1.11e-2)" "unprognostic (1.31e-2)" "unprognostic (4.40e-2)" "unprognostic (3.63e-1)" "unprognostic (6.01e-2)" "unprognostic (3.70e-2)" "unprognostic (2.85e-2)" "unprognostic (2.11e-2)" "unprognostic (3.96e-2)" "unprognostic (6.74e-3)" "unprognostic (2.49e-1)" "unprognostic (4.44e-2)" "unprognostic (2.40e-2)" "unprognostic (3.81e-1)" "unprognostic (5.22e-2)" "unprognostic (1.29e-1)" 17.0 11.8 6.6 14.6 7.7 5.2 20.8 9.4 10.0 17.6 10.4 11.2 7.5 18.8 9.4 19.1 15.8 15.1 9.0 6.5 7.6 16.2 18.8 13.6 17.5 7.5 7.1 22.1 10.2 20.3 6.4 13.9 8.6 17.6 11.3 18.0 12.2 17.5 6.7 11.4 9.7 17.3 7.1 18.6 11.2 37.4 6.8 11.8 27.3 7.0 16.2 14.6 9.7 11.1 29.5 17.9 23.6 40.8 27.1 47.8 14.2 38.3 34.7 28.1 22.2 11.2 36.2 73.1 12.6 44.2 21.0 15.8 26.9 33.3 37.2 65.3 17.7 29.5 10.5 26.1 33.5 40.5 22.4 31.0 45.9 30.6 66.6 34.9 24.6 33.7 53.1 66.8 39.9 14.0 21.5 20.0 13.6 9.1 14.2 31.9 11.7 45.8 34.4 15.6 15.8 42.3 28.3 27.2 53.9 13.6 18.2 24.4 35.8 26.4 16.4 10.4 30.4 26.4 12.5 22.4 33.0 34.5 53.8 9.5 6.4 2.9 27.8 11.5 32.8 30.7 27.0 27.4 8.5 29.7 27.0 18.9 1.3 19.9 18.9 29.3 21.0 10.0 6.6 7.7 9.4 10.0 6.5 7.6 7.5 7.1 8.6 7.1 6.8 11.1 84.0 64.1 41.3 17.0 50.5 0.0 64.7 0.0 58.6 61.5 68.5 75.4 29.6 52.9 22.9 46.0 52.1 29.5 54.4 2.8 70.5 57.2 276.4 66.9 81.7 49.9 12.2 30.1 10.8 51.5 33.8 53.0 34.7 39.3 27.8 39.7 41.4 65.1 20.7 69.0 19.3 11.6 0.0 26.3 0.0 156.3 81.7 25.7 0.0 15.0 41.0 61.9 63.8 26.2 20.3 49.1 6.6 87.6 41.9 73.0 15.0 109.2 36.5 69.6 72.3 75.5 51.4 171.7 109.3 48.3 0.0 15.7 47.7 122.0 14.8 37.8 CGNL1 "FLJ14957, JACOP, KIAA1749, PCING" ENSG00000128849 "Cingulin like 1" Q0VF96 15 57375967-57550717 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 68.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 87.2;Astrocytes: 79.7;Hepatic stellate cells: 58.5;Hepatocytes: 65.5;Microglial cells: 156.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 52.7;SuSa: 37.6;TIME: 32.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013500, HPA056911, HPA069214" Enhanced Supported "Nuclear bodies,Cell Junctions" No No "Cluster 15: Liver - Metabolism" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 11: Alveolar cells - Smell perception" "Cell Junctions" "Nuclear bodies" "CAB013500: , HPA056911: AB_2683274, HPA069214: AB_2686102" "unprognostic (1.04e-2)" "unprognostic (2.42e-1)" "unprognostic (1.52e-2)" "prognostic favorable (3.55e-4)" "unprognostic (3.22e-1)" "unprognostic (1.51e-3)" "prognostic favorable (5.58e-4)" "unprognostic (4.32e-2)" "unprognostic (2.34e-1)" "unprognostic (4.86e-2)" "unprognostic (4.05e-2)" "unprognostic (1.91e-2)" "prognostic favorable (1.37e-6)" "unprognostic (2.26e-2)" "unprognostic (3.39e-1)" "unprognostic (1.88e-3)" "unprognostic (1.18e-2)" 5.0 11.5 23.6 1.5 23.0 0.0 19.8 19.8 18.5 32.0 47.2 3.2 1.2 17.8 4.4 11.0 8.9 2.8 20.1 18.6 24.2 68.3 36.0 21.0 1.1 28.9 28.2 5.8 18.6 9.6 4.1 28.8 27.7 28.7 2.3 12.3 32.3 16.2 0.7 11.5 2.5 10.8 20.0 0.4 15.5 6.6 29.9 4.6 19.8 1.9 3.2 8.9 20.2 15.7 0.0 1.3 13.1 0.0 0.0 0.0 0.2 0.2 2.9 1.1 2.4 8.4 0.1 0.0 11.4 1.7 1.9 0.0 6.2 0.1 1.8 0.1 1.0 0.1 0.1 5.7 0.2 0.1 0.0 0.4 0.4 1.3 0.0 4.4 52.7 0.5 0.0 0.0 2.1 2.4 0.0 0.2 6.5 3.7 0.6 0.1 6.6 0.3 4.4 0.0 0.3 0.7 0.0 5.1 0.0 37.6 0.5 0.6 32.5 0.0 3.3 0.1 1.9 0.0 0.0 0.0 0.2 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.6 23.0 19.8 18.5 18.6 24.2 28.9 28.2 27.7 20.0 29.9 15.7 3.9 51.3 87.2 79.7 0.2 4.6 13.4 5.1 4.6 0.4 27.4 27.1 21.0 10.0 11.7 22.0 0.0 1.0 1.6 0.9 41.1 9.9 3.0 11.0 9.4 21.8 13.1 2.7 0.7 13.2 1.0 17.1 11.2 11.8 1.3 3.5 58.5 65.5 0.3 0.0 1.9 3.7 18.3 1.6 4.9 18.1 19.9 0.9 7.2 156.4 0.6 43.7 0.0 11.1 1.5 4.3 1.2 27.8 0.0 18.6 0.2 39.4 2.2 1.4 0.0 6.6 2.3 0.6 0.6 0.8 2.4 1.4 1.2 0.6 2.2 7.0 CHD5 ENSG00000116254 "Chromodomain helicase DNA binding protein 5" Q8TDI0 1 6101787-6180321 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Differentiation, Neurogenesis, Spermatogenesis, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 59.0;pituitary gland: 57.3;testis: 31.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 84.3;Early spermatids: 217.8;Excitatory neurons: 80.4;Horizontal cells: 225.4;Inhibitory neurons: 56.2;Late spermatids: 113.2;Rod photoreceptor cells: 49.9" "Cancer enhanced" "Detected in single" "glioma: 0.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "SCLC-21H: 12.9;U-2 OS: 5.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015809 Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 62: Horizontal cells - Visual perception" "Nucleoplasm, Nuclear speckles" Cytosol "HPA015809: " "unprognostic (5.03e-4)" "unprognostic (1.89e-1)" "unprognostic (2.47e-3)" "unprognostic (9.40e-6)" "unprognostic (1.91e-2)" "unprognostic (2.98e-2)" "unprognostic (1.06e-1)" "unprognostic (1.09e-1)" "unprognostic (2.97e-2)" "unprognostic (1.95e-2)" "unprognostic (6.64e-4)" "unprognostic (1.34e-1)" "unprognostic (1.34e-4)" "unprognostic (1.16e-1)" "unprognostic (1.63e-1)" "unprognostic (1.96e-1)" "unprognostic (1.98e-1)" 0.2 4.1 31.8 0.2 40.1 0.0 0.1 0.0 59.0 0.4 0.0 1.1 0.2 0.4 0.0 0.3 0.4 0.1 0.4 34.3 13.6 2.4 0.1 0.3 0.0 3.9 11.1 0.5 0.4 0.9 57.3 0.0 4.4 0.9 0.2 7.9 0.2 2.2 0.2 0.3 0.4 0.1 0.9 0.1 1.0 31.8 10.2 0.3 0.1 0.0 0.0 0.7 0.6 31.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.6 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 2.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.2 1.2 0.0 0.1 0.2 1.1 0.0 0.0 0.0 0.0 12.9 0.2 0.1 0.0 0.0 0.0 2.3 0.0 0.0 0.1 5.7 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.8 40.1 0.0 59.0 34.3 13.6 3.9 11.1 4.4 0.9 10.2 31.1 0.0 0.0 0.0 5.5 0.1 0.1 0.1 0.0 0.0 84.3 0.1 0.3 2.1 0.0 0.0 3.7 12.5 0.0 0.1 0.2 0.0 0.0 217.8 0.0 0.2 0.6 0.0 0.0 80.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 225.4 56.2 0.0 0.0 0.0 0.3 113.2 0.9 0.1 0.0 2.8 0.0 2.0 0.0 4.5 3.7 0.3 0.0 0.4 0.0 0.2 0.0 0.1 0.0 49.9 0.0 0.2 0.5 4.5 17.8 0.0 0.4 0.0 0.1 0.1 0.0 0.0 CHEK1 CHK1 ENSG00000149554 "Checkpoint kinase 1" O14757 11 125625665-125676255 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 25.7;lymphoid tissue: 20.7;seminal vesicle: 29.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 32.9;Erythroid cells: 34.5;Extravillous trophoblasts: 35.6;Spermatocytes: 48.9;Spermatogonia: 49.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "T-reg: 6.2" "Group enriched" "Detected in many" 5 "granulocytes: 1.7;T-cells: 6.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA044364 Supported Nucleoplasm,Vesicles NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Vesicles "HPA044364: AB_2678913" "unprognostic (6.74e-2)" "unprognostic (3.63e-1)" "prognostic favorable (3.62e-4)" "unprognostic (5.54e-2)" "unprognostic (2.17e-1)" "unprognostic (1.03e-1)" "prognostic unfavorable (3.70e-6)" "unprognostic (3.95e-3)" "unprognostic (1.26e-3)" "unprognostic (2.54e-2)" "prognostic unfavorable (3.10e-6)" "unprognostic (1.75e-1)" "prognostic unfavorable (1.04e-8)" "unprognostic (2.89e-2)" "unprognostic (2.64e-1)" "unprognostic (8.16e-2)" "unprognostic (1.33e-1)" 1.6 1.3 0.7 8.2 1.0 25.7 2.6 0.6 1.3 1.7 0.5 7.9 6.8 1.7 6.7 4.1 1.1 1.7 0.9 0.7 0.9 2.2 2.1 1.3 14.9 0.7 0.8 1.8 2.0 13.2 1.7 4.8 0.8 1.6 8.7 0.7 1.5 29.8 0.6 3.6 7.3 3.4 0.6 2.2 2.6 8.9 1.2 20.7 1.0 1.3 13.9 3.3 2.1 0.8 48.5 37.0 81.1 47.4 13.5 28.9 35.7 61.1 28.7 41.6 40.1 88.0 100.3 120.7 63.5 24.9 53.7 52.6 54.2 33.2 50.1 81.4 24.8 224.2 27.2 44.7 4.3 121.1 39.6 15.7 6.0 47.6 36.0 19.9 44.7 84.1 117.3 102.7 51.4 23.8 181.3 65.0 86.1 77.1 33.2 104.7 74.4 67.2 37.9 63.2 50.5 53.6 45.2 35.4 15.2 57.3 93.9 40.6 28.4 51.0 47.3 29.6 60.8 21.9 45.4 187.5 20.5 86.6 67.6 1.7 0.2 0.0 0.4 0.1 0.2 0.7 1.6 0.4 0.6 0.3 0.4 0.3 1.1 0.3 0.1 0.7 6.2 0.4 0.7 1.0 0.6 1.3 0.7 0.9 0.7 0.8 0.8 0.6 1.2 0.8 1.1 3.2 0.5 1.6 5.5 6.2 3.9 5.8 5.2 1.7 3.9 6.0 4.6 32.9 4.1 7.3 0.0 17.3 6.0 4.5 3.9 3.4 7.8 5.5 8.0 3.5 1.8 34.5 3.3 1.1 35.6 5.3 6.1 9.9 0.0 21.1 3.6 1.2 11.1 0.0 2.5 9.2 2.0 0.0 5.2 3.1 1.5 3.2 0.0 2.8 3.2 2.8 3.1 1.5 1.6 2.9 3.9 1.2 17.7 3.1 8.0 9.4 2.5 1.7 0.0 3.1 7.8 48.9 49.8 9.5 4.8 7.8 5.1 4.8 16.7 3.0 CHGA ENSG00000100604 "Chromogranin A" P10645 14 92923150-92935285 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins" "Antibiotic, Antimicrobial, Fungicide" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "parathyroid gland: 6568.4" "Cell type enriched" "Detected in many" 7 "Enteroendocrine cells: 6553.1" "Cancer enhanced" "Detected in many" "pancreatic cancer: 114.8" "Group enriched" "Detected in many" 16 "cerebral cortex: 326.0;white matter: 124.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 151 "SCLC-21H: 489.5;SH-SY5Y: 1339.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000023, HPA017369, CAB040544, CAB055506, CAB058688" Enhanced Supported Vesicles "Intracellular and membrane" NA NA 295000000 100000000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 17: Intestinal endocrine cells - Hormone signaling" Vesicles "CAB000023: , CAB040544: , CAB055506: AB_2081135, CAB058688: AB_2665574, HPA017369: AB_1846698" "prognostic favorable (7.85e-5)" "unprognostic (4.89e-2)" "unprognostic (5.96e-2)" "unprognostic (1.17e-1)" "unprognostic (1.43e-2)" "unprognostic (5.95e-2)" "prognostic unfavorable (2.40e-4)" "unprognostic (1.74e-1)" "unprognostic (2.23e-1)" "unprognostic (4.56e-2)" "prognostic favorable (4.07e-4)" "unprognostic (1.85e-1)" "unprognostic (8.81e-13)" "unprognostic (1.07e-2)" "unprognostic (1.77e-1)" "unprognostic (9.17e-2)" "prognostic unfavorable (3.99e-4)" 14.5 1248.5 8.6 9.4 11.4 0.2 0.3 0.0 326.0 8.3 0.0 92.0 242.7 0.4 0.3 1.0 1.1 0.2 0.2 4.4 1.7 1.0 0.4 1.6 0.1 14.4 0.0 0.2 102.5 6568.4 446.2 0.0 4.1 12.2 105.2 11.0 0.2 0.3 0.1 0.6 179.9 0.9 0.0 0.1 364.5 77.7 4.3 0.6 24.6 0.0 0.0 1.3 1.2 124.4 0.0 0.5 2.4 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.8 2.7 0.0 0.0 0.2 0.0 1.4 0.0 0.0 489.5 1339.4 0.0 0.4 0.1 0.0 0.1 0.1 0.0 0.0 4.2 0.3 0.4 0.0 0.0 0.8 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 11.4 0.0 326.0 4.4 1.7 14.4 0.0 4.1 0.0 4.3 124.4 0.1 0.0 0.0 11.1 1.0 0.9 0.4 0.0 0.0 17.3 0.2 0.3 2.9 0.0 0.0 0.0 29.2 0.3 0.0 9.8 0.0 0.1 1.3 6.0 2.3 0.8 6553.1 0.0 59.5 0.4 0.1 4.1 195.7 0.5 0.0 0.5 0.0 0.0 1.5 16.8 37.7 820.4 14.2 0.0 0.0 7.9 39.7 0.1 7.2 15.9 2.0 3.7 0.0 10.6 12.8 46.5 137.8 137.3 0.0 6.6 36.7 0.0 0.0 16.2 0.0 0.0 0.2 4.7 2.2 0.0 0.0 0.3 0.2 0.4 25.9 5.1 CHGB "SCG1, SgI" ENSG00000089199 "Chromogranin B" P05060 20 5911510-5925353 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 13 "adrenal gland: 3466.0;pituitary gland: 1425.3" "Cell type enriched" "Detected in many" 5 "Enteroendocrine cells: 1036.1" "Cancer enriched" "Detected in many" 6 "pancreatic cancer: 154.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 23 "SCLC-21H: 355.0;SH-SY5Y: 541.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008759, CAB009403, HPA012602" Enhanced Supported Enhanced Vesicles "Intracellular and membrane" NA NA 6500000 "Cluster 20: T-cells - T-cell receptor" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 17: Intestinal endocrine cells - Hormone signaling" Vesicles "CAB009403: AB_2081255, HPA008759: AB_1846704, HPA012602: AB_1846706" "unprognostic (1.79e-3)" "unprognostic (7.72e-2)" "unprognostic (3.48e-1)" "unprognostic (2.90e-2)" "unprognostic (1.68e-2)" "prognostic unfavorable (1.89e-4)" "unprognostic (7.96e-3)" "unprognostic (2.86e-1)" "unprognostic (6.18e-3)" "unprognostic (7.93e-2)" "prognostic favorable (9.96e-4)" "unprognostic (8.56e-2)" "unprognostic (8.21e-2)" "unprognostic (1.56e-1)" "unprognostic (2.81e-2)" "unprognostic (2.73e-1)" "unprognostic (1.01e-2)" 27.5 3466.0 17.1 5.3 9.9 0.8 2.1 134.2 90.9 0.6 0.0 7.9 60.2 1.6 4.2 0.6 13.7 0.4 71.9 101.9 92.2 8.3 0.7 2.4 3.1 76.5 100.2 25.8 92.8 6.4 1425.3 0.7 188.4 5.3 14.2 56.9 6.1 3.8 11.0 1.7 31.6 0.9 12.8 0.3 133.3 14.9 19.3 4.0 9.7 0.8 1.4 0.4 2.3 14.2 0.0 7.9 0.9 0.0 0.2 0.2 0.4 0.2 0.0 0.1 0.0 1.9 0.0 0.0 4.3 0.0 4.9 0.1 0.0 0.1 0.1 0.6 0.1 2.6 0.0 1.6 0.1 4.2 0.2 1.5 0.0 0.0 2.1 0.1 0.1 0.2 0.4 0.1 1.0 0.0 0.1 0.9 19.7 1.3 0.0 0.1 0.0 0.4 0.5 0.2 355.0 541.8 0.0 0.5 0.4 2.1 0.3 0.4 0.3 0.1 6.4 0.4 3.3 0.0 0.7 2.7 0.5 3.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 17.1 9.9 134.2 90.9 101.9 92.2 76.5 100.2 188.4 12.8 19.3 14.2 0.0 3.2 2.4 7.5 0.3 4.2 9.9 0.8 0.0 93.3 0.1 0.3 114.4 0.0 0.7 69.9 20.9 0.1 0.0 1.6 1.9 0.5 7.1 0.2 0.7 3.0 1036.1 0.0 31.6 0.4 0.0 18.9 4.1 0.3 0.0 202.8 0.0 0.3 0.1 75.7 28.8 61.9 65.1 0.3 9.5 8.3 0.9 1.6 7.2 9.4 1.1 13.7 1.0 7.5 5.2 22.9 17.7 0.4 0.0 3.3 3.2 0.3 4.4 75.6 13.1 3.0 1.6 76.6 41.8 0.0 3.7 0.3 1.0 3.0 2.2 4.2 CHIC2 BTL ENSG00000109220 "Cysteine rich hydrophobic domain 2" Q9UKJ5 4 54009789-54064605 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 348.7;Suprabasal keratinocytes: 373.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Lineage enriched" "Detected in all" 4 "granulocytes: 365.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026782, HPA026784, HPA076603" Uncertain Enhanced "Vesicles,Plasma membrane" NA Yes "Cluster 38: Basophils - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 30: Epithelial cell lines - Translation" "Cluster 28: Keratinocytes - Keratinization" "Vesicles, Plasma membrane" "HPA026782: AB_1846654, HPA026784: AB_2732433, HPA076603: AB_2732317" "unprognostic (4.56e-2)" "unprognostic (2.24e-3)" "unprognostic (3.47e-3)" "unprognostic (9.58e-2)" "unprognostic (1.49e-1)" "unprognostic (2.25e-2)" "unprognostic (7.87e-2)" "unprognostic (1.22e-1)" "unprognostic (3.65e-2)" "unprognostic (7.81e-3)" "unprognostic (2.94e-2)" "unprognostic (5.63e-2)" "prognostic unfavorable (1.56e-4)" "unprognostic (2.89e-1)" "unprognostic (1.77e-1)" "unprognostic (4.56e-2)" "unprognostic (9.40e-2)" 20.8 15.9 9.1 12.9 8.5 27.1 18.1 12.6 9.6 16.0 12.1 12.4 12.3 12.3 10.3 27.4 12.1 20.5 15.1 8.6 9.2 14.2 20.3 19.7 14.7 8.6 8.5 13.0 9.9 6.5 9.3 13.5 9.0 12.9 8.9 5.9 15.2 5.7 9.8 27.5 13.2 10.5 7.8 17.3 12.9 39.6 9.2 21.9 11.9 6.6 13.3 15.1 18.1 9.7 25.4 4.6 12.8 11.9 21.5 16.8 13.1 34.6 36.1 20.1 20.3 18.1 22.0 21.4 29.5 22.0 17.2 7.7 17.9 25.1 22.0 11.9 9.5 11.7 4.2 13.6 65.1 19.2 23.4 22.6 19.8 30.3 45.3 38.3 30.0 22.2 13.0 15.4 40.6 7.1 22.3 30.7 8.7 11.2 16.9 14.3 7.3 8.4 23.3 8.1 19.7 18.3 8.3 12.2 26.6 18.3 6.1 26.8 51.3 25.2 19.9 36.6 21.4 18.4 9.5 17.2 18.7 18.7 18.7 365.5 79.3 171.5 60.1 64.7 57.7 41.3 60.0 68.6 55.9 40.1 54.6 59.6 325.0 74.2 68.3 47.0 81.5 77.9 9.1 8.5 12.6 9.6 8.6 9.2 8.6 8.5 9.0 7.8 9.2 9.7 58.1 6.4 7.3 35.6 42.5 348.7 95.5 61.0 68.3 8.1 61.6 33.5 4.1 15.7 25.9 7.3 8.4 27.8 57.8 27.2 17.6 42.8 55.4 64.1 58.0 64.3 25.8 72.6 39.7 28.0 38.7 80.8 32.6 34.2 36.3 36.8 38.6 23.9 24.7 13.5 40.2 21.9 40.7 36.4 144.2 13.4 17.1 50.3 67.6 49.6 32.6 9.0 28.8 74.4 23.2 61.8 42.1 24.5 40.2 85.1 41.9 29.2 56.0 7.2 19.7 53.9 45.1 163.5 89.9 97.4 373.8 47.7 65.8 39.8 21.0 135.9 CHODL "C21orf68, FLJ12627, MT75, PRED12" ENSG00000154645 Chondrolectin Q9H9P2 21 17901263-18267373 "Predicted intracellular proteins, Predicted membrane proteins" Neurogenesis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.5;lymphoid tissue: 14.1;testis: 31.0" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 38.6;Oligodendrocytes: 50.1;Skeletal myocytes: 28.3;Theca cells: 26.7" "Cancer enhanced" "Detected in many" "ovarian cancer: 6.9" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 4 "MAIT T-cell: 1.5" "Lineage enriched" "Detected in single" 7 "T-cells: 1.5" "Cell line enhanced" "Detected in some" "HDLM-2: 1.8;U-266/70: 2.8;U-266/84: 7.2;U-87 MG: 7.8" "Group enriched" "Detected in many" 4 "basal ganglia: 3.9;hypothalamus: 12.3;pons and medulla: 10.9" "Group enriched" "Detected in all" 4 "olfactory bulb: 66.4;spinal cord: 38.6" "HPA017282, HPA057559" Enhanced Approved Centrosome,Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 16: U-266 - Nucleosome" "Cluster 36: Stromal cells - Cell proliferation" Cytosol Centrosome "HPA017282: AB_1846687, HPA057559: " "unprognostic (3.91e-1)" "unprognostic (3.18e-2)" "unprognostic (2.37e-2)" "prognostic unfavorable (1.18e-6)" "unprognostic (6.74e-2)" "unprognostic (6.82e-2)" "unprognostic (1.06e-3)" "unprognostic (6.79e-2)" "unprognostic (8.37e-2)" "unprognostic (1.03e-1)" "unprognostic (1.49e-2)" "unprognostic (1.57e-1)" "unprognostic (1.12e-3)" "unprognostic (1.36e-2)" "unprognostic (1.87e-1)" "unprognostic (4.83e-2)" "unprognostic (1.02e-1)" 3.3 2.0 1.6 1.1 1.4 0.0 1.1 0.7 1.6 0.2 0.8 2.8 1.6 0.6 1.1 0.9 0.5 0.8 3.7 1.7 5.4 3.6 0.0 0.3 0.4 11.5 2.6 0.6 0.1 0.3 2.5 1.9 10.8 5.6 3.5 0.6 0.5 1.8 0.6 2.3 1.0 0.3 1.6 14.1 0.7 31.0 10.2 0.3 1.1 1.7 1.2 0.7 1.1 3.8 0.0 0.0 0.6 0.0 0.0 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.0 1.8 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.0 0.4 0.1 1.4 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.7 0.6 0.9 0.0 0.1 0.1 0.1 0.1 0.0 0.0 2.8 7.2 0.2 7.8 0.0 0.1 0.0 0.0 0.0 0.2 0.0 1.5 0.1 0.1 0.2 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.2 0.3 0.1 1.6 1.4 0.7 1.6 1.7 5.4 11.5 2.6 10.8 1.6 10.2 3.8 1.7 0.0 0.0 5.2 1.0 4.0 0.8 0.8 3.4 1.1 1.0 1.3 0.5 0.0 0.9 0.0 0.0 0.2 0.9 0.0 1.9 0.4 5.0 1.4 38.6 1.5 0.0 0.0 5.5 0.0 0.2 4.6 0.0 0.8 0.0 12.3 0.0 0.0 0.1 0.0 3.2 0.0 0.0 0.0 0.8 4.0 3.1 0.1 1.8 4.7 0.0 0.4 0.0 12.5 50.1 0.0 0.0 1.9 3.1 0.2 0.0 0.3 0.3 0.1 0.0 28.3 10.5 1.3 1.7 0.5 2.3 0.5 1.3 26.7 0.1 0.3 CHP2 ENSG00000166869 "Calcineurin like EF-hand protein 2" O43745 16 23755026-23758935 "Cancer-related genes, Predicted intracellular proteins" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 16 "intestine: 305.0;skin 1: 149.7" "Group enriched" "Detected in some" 5 "Distal enterocytes: 345.0;Paneth cells: 274.0;Proximal enterocytes: 654.2;Undifferentiated cells: 205.4" "Cancer enhanced" "Detected in many" "colorectal cancer: 10.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-HME1: 7.3;hTERT-RPE1: 10.2;NB-4: 8.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA055198, CAB072806" Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 24: NB-4 - Immune response" "Cluster 45: Enterocytes - Digestion" Nucleoplasm "Nucleoli, Cytosol" "CAB072806: , HPA055198: " "unprognostic (4.82e-1)" "unprognostic (3.40e-1)" "unprognostic (4.93e-2)" "unprognostic (1.01e-2)" "unprognostic (8.85e-2)" "unprognostic (3.54e-1)" "unprognostic (4.54e-2)" "unprognostic (1.47e-1)" "unprognostic (1.38e-1)" "unprognostic (5.31e-2)" "unprognostic (4.70e-2)" "unprognostic (1.44e-5)" "unprognostic (2.21e-1)" "unprognostic (5.97e-2)" "unprognostic (7.84e-2)" "unprognostic (9.01e-2)" 0.4 0.2 1.1 3.8 1.1 2.2 4.3 3.6 1.3 14.0 0.0 146.7 305.0 0.9 1.1 0.6 0.9 0.4 0.4 0.7 1.6 4.1 0.7 0.6 0.8 0.5 0.1 0.4 0.5 0.1 0.0 1.4 0.9 3.8 147.4 1.3 0.8 4.5 1.2 149.7 250.5 6.5 0.1 0.3 1.1 7.3 0.9 0.5 0.6 0.2 0.4 9.0 4.2 2.9 1.0 2.2 0.5 0.6 1.2 1.3 1.2 2.9 1.1 0.3 1.0 0.5 2.3 0.4 0.9 2.5 1.2 1.4 0.4 2.9 0.6 0.7 0.2 0.5 4.1 1.6 1.7 0.3 0.7 0.9 0.8 2.5 7.3 10.2 1.1 0.3 1.2 1.0 1.2 0.1 0.1 8.7 0.3 0.5 2.1 0.2 0.1 1.4 1.1 0.7 0.6 0.7 0.8 0.2 0.0 0.6 0.2 0.2 1.3 0.5 0.6 0.7 0.1 0.4 0.1 0.2 0.0 0.5 0.5 0.1 0.1 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.4 0.0 0.1 0.1 0.0 0.0 1.1 1.1 3.6 1.3 0.7 1.6 0.5 0.1 0.9 0.1 0.9 2.9 0.0 0.0 0.0 0.0 0.0 10.3 8.7 6.1 0.0 0.0 0.0 0.1 0.1 0.0 24.4 1.8 0.0 0.9 0.0 345.0 0.0 0.0 0.6 1.3 0.5 0.2 9.1 0.0 0.0 0.0 4.1 0.2 0.0 3.6 4.5 0.7 0.0 0.0 0.1 0.0 0.0 70.0 12.2 0.0 1.6 0.5 0.0 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.6 0.0 274.0 0.0 0.0 2.5 654.2 12.9 4.4 0.0 0.0 0.0 0.3 0.0 0.2 0.0 67.5 0.7 0.2 0.2 205.4 29.9 CHRD ENSG00000090539 Chordin Q9H2X0 3 184380073-184390736 "Plasma proteins, Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 130.0" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 31.2;Excitatory neurons: 28.2;Fibroblasts: 16.4;Hepatocytes: 36.4;Inhibitory neurons: 37.5;Skeletal myocytes: 19.1;Smooth muscle cells: 16.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 2.8;Hep G2: 11.8;MCF7: 2.5;SuSa: 4.0;U-2 OS: 3.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA035827 Approved "Secreted in other tissues" NA NA 350000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 36: Stromal cells - Cell proliferation" "HPA035827: AB_10669657" "unprognostic (2.26e-1)" "unprognostic (3.25e-2)" "unprognostic (1.63e-2)" "unprognostic (2.21e-1)" "unprognostic (6.52e-2)" "unprognostic (3.16e-1)" "unprognostic (2.88e-1)" "unprognostic (9.58e-2)" "unprognostic (1.87e-1)" "unprognostic (1.12e-1)" "unprognostic (3.12e-2)" "unprognostic (6.55e-2)" "prognostic unfavorable (6.09e-7)" "unprognostic (5.53e-3)" "unprognostic (1.85e-1)" "unprognostic (9.84e-2)" "unprognostic (7.99e-3)" 11.1 12.2 13.9 2.1 13.9 0.0 9.9 19.0 21.2 40.0 9.1 7.6 1.6 32.9 3.2 3.3 15.0 2.5 11.2 15.1 9.4 18.8 130.0 7.2 1.5 10.1 9.9 16.3 17.1 1.1 6.0 2.4 10.2 9.7 0.8 0.0 3.8 5.2 4.4 5.4 6.0 4.6 10.3 9.7 7.8 1.1 9.7 0.2 7.7 2.7 0.3 7.2 15.4 13.6 0.0 0.0 0.3 1.1 0.1 0.1 1.4 0.3 0.0 0.2 0.1 2.8 0.0 0.0 1.1 0.3 1.0 0.0 1.7 0.0 0.0 0.0 0.7 0.0 0.0 11.8 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 1.5 2.0 0.0 0.0 0.6 0.0 0.1 0.1 0.1 4.0 1.4 0.0 0.0 0.0 3.8 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.9 13.9 19.0 21.2 15.1 9.4 10.1 9.9 10.2 10.3 9.7 13.6 2.6 0.0 0.0 11.8 0.4 2.7 0.0 0.0 0.6 2.9 2.1 1.8 3.1 0.0 0.0 1.8 0.0 0.1 0.0 0.0 0.0 0.1 0.1 3.6 31.2 2.6 0.0 0.0 28.2 3.1 0.0 16.4 1.1 4.5 0.0 0.9 3.3 36.4 0.7 0.0 37.5 0.2 0.0 3.2 3.1 0.0 3.7 0.4 1.8 4.7 0.0 0.0 0.0 7.1 2.5 1.1 0.0 2.2 0.0 0.1 0.0 4.0 0.0 0.5 6.6 19.1 16.4 0.3 0.3 0.3 1.1 0.1 0.7 0.1 0.0 0.3 CHRNB3 ENSG00000147432 "Cholinergic receptor nicotinic beta 3 subunit" Q05901 8 42697366-42737407 "Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 4 "brain: 12.1;retina: 3.8" "Cell type enhanced" "Detected in some" "Astrocytes: 1.0;Bipolar cells: 1.5;Excitatory neurons: 2.2;Inhibitory neurons: 2.9;Microglial cells: 1.0;Rod photoreceptor cells: 1.1" "Cancer enriched" "Detected in single" 11 "testis cancer: 0.6" "Group enriched" "Detected in many" 5 "cerebellum: 12.1;midbrain: 10.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "NTERA-2: 1.1;U-266/84: 2.7" "Region enhanced" "Detected in many" "midbrain: 6.9" "Low region specificity" "Detected in all" HPA045555 Enhanced NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 16: U-266 - Nucleosome" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA045555: AB_10960891" "unprognostic (8.63e-2)" "unprognostic (4.12e-1)" "unprognostic (7.29e-2)" "unprognostic (1.62e-1)" 0.0 0.0 0.2 0.0 1.7 0.0 0.0 12.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 2.2 0.0 0.0 0.0 0.1 0.0 10.2 0.0 1.8 0.0 0.1 0.0 0.2 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 1.7 12.1 0.3 0.5 2.2 0.0 10.2 0.2 0.0 0.4 0.4 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.0 0.0 0.5 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 CHRNE ACHRE ENSG00000108556 "Cholinergic receptor nicotinic epsilon subunit" Q04844 17 4897771-4934438 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "heart muscle: 55.3;pituitary gland: 27.6" "Cell type enriched" "Detected in many" 5 "Late spermatids: 161.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "gdT-cell: 2.5" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 9 "HEL: 5.0;HMC-1: 11.5" "Not detected" "Not detected" "Region enriched" "Detected in single" 14 "basal ganglia: 6.3" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 3: HMC-1 - Innate immune response" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (2.00e-3)" "unprognostic (1.56e-1)" "unprognostic (3.94e-2)" "unprognostic (4.35e-3)" "unprognostic (6.55e-2)" "unprognostic (2.27e-3)" "unprognostic (7.80e-4)" "unprognostic (7.75e-2)" "unprognostic (3.24e-1)" "unprognostic (1.34e-1)" "unprognostic (3.69e-2)" "unprognostic (6.58e-2)" "unprognostic (8.42e-4)" "unprognostic (1.39e-3)" "unprognostic (1.26e-1)" "unprognostic (5.83e-2)" "unprognostic (5.70e-2)" 0.7 0.4 0.1 0.4 0.1 0.7 0.7 0.6 0.4 0.7 0.0 0.3 0.3 0.4 1.3 0.4 0.6 1.0 55.3 0.2 0.1 1.0 3.5 0.8 0.5 0.3 0.0 0.8 1.7 0.2 27.6 0.6 0.1 0.6 0.0 5.1 0.8 0.2 1.8 2.2 0.8 0.2 0.0 1.8 0.5 0.7 0.1 0.1 0.4 2.1 0.2 0.3 0.5 0.2 0.0 0.0 0.4 0.0 0.0 0.1 0.4 0.2 0.0 0.0 0.1 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 5.0 0.0 0.8 0.4 0.0 11.5 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.2 1.3 2.5 0.4 0.0 0.0 0.1 0.8 0.2 0.4 0.1 0.7 1.1 0.8 0.6 0.1 0.0 0.7 0.1 0.1 0.6 0.4 0.2 0.1 0.3 0.0 0.1 0.0 0.1 0.2 4.9 0.0 0.0 0.3 4.2 1.7 1.4 0.8 1.2 5.0 1.6 2.0 6.5 1.5 0.6 1.8 4.2 0.6 10.2 0.0 1.9 0.3 27.8 0.6 1.1 3.3 0.0 0.0 0.5 0.9 7.3 2.3 1.1 0.8 8.2 1.4 2.9 7.4 3.4 3.3 0.4 0.1 2.0 1.3 13.0 161.5 0.9 9.9 0.0 2.8 5.3 1.1 8.2 0.5 0.7 0.7 0.0 0.4 3.5 1.1 0.0 2.9 0.6 10.0 0.0 0.9 1.1 5.6 8.4 0.2 1.1 11.1 3.5 6.2 0.2 0.7 CHST9 "GALNAC-4-ST2, GALNAC4ST-2" ENSG00000154080 "Carbohydrate sulfotransferase 9" Q7L1S5 18 26906481-27185308 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carbohydrate metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 13.8" "Cell type enhanced" "Detected in many" "Club cells: 115.2;Muller glia cells: 69.2;Oligodendrocyte precursor cells: 167.4;Respiratory ciliated cells: 311.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 9.3;Hep G2: 13.8;RPTEC TERT1: 41.8;SCLC-21H: 9.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA011393 Uncertain "Intracellular and membrane" NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 49: Ciliated cells - Cilium organization" "HPA011393: AB_1846733" "unprognostic (9.24e-3)" "unprognostic (1.13e-2)" "unprognostic (4.81e-3)" "unprognostic (6.63e-3)" "unprognostic (4.53e-3)" "unprognostic (9.98e-3)" "unprognostic (9.21e-3)" "unprognostic (7.92e-2)" "unprognostic (1.61e-1)" "unprognostic (2.04e-2)" "unprognostic (3.54e-2)" "unprognostic (2.72e-2)" "unprognostic (2.17e-2)" "unprognostic (1.38e-1)" "unprognostic (3.93e-3)" 0.0 0.2 0.8 0.1 0.9 0.0 2.9 0.7 2.4 2.8 0.0 1.6 0.2 0.1 0.4 1.6 10.3 3.1 2.6 2.7 1.2 1.6 8.2 4.3 0.0 3.5 2.3 0.0 9.3 0.0 1.9 0.0 1.2 3.5 0.2 7.3 13.8 1.8 0.2 0.1 0.3 0.1 2.0 5.7 0.7 6.9 1.2 1.0 0.0 0.9 0.6 1.5 0.7 1.9 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.3 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.1 0.0 0.0 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 41.8 0.0 9.0 0.4 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.9 0.7 2.4 2.7 1.2 3.5 2.3 1.2 2.0 1.2 1.9 0.1 0.0 2.7 24.8 0.0 0.6 32.6 56.6 4.6 1.3 8.2 8.0 9.2 35.8 115.2 5.5 0.0 0.4 0.1 0.0 11.7 13.0 7.1 49.9 0.7 0.3 3.5 0.0 10.1 0.6 0.1 4.2 0.0 1.8 5.1 0.1 0.0 10.7 0.3 0.0 29.3 0.1 22.4 0.0 0.0 4.4 0.6 0.5 7.2 1.0 0.0 69.2 0.0 167.4 1.0 1.3 0.0 0.4 0.0 8.9 0.0 0.3 311.6 3.2 0.0 3.2 3.7 0.9 1.3 4.7 0.0 0.3 0.4 0.0 0.0 40.3 CINP MGC849 ENSG00000100865 "Cyclin dependent kinase 2 interacting protein" Q9BW66 14 102341102-102362916 "Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, DNA replication" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (3.47e-1)" "unprognostic (2.84e-1)" "unprognostic (1.50e-2)" "unprognostic (8.07e-2)" "unprognostic (2.19e-1)" "unprognostic (2.17e-3)" "unprognostic (1.44e-2)" "unprognostic (2.45e-1)" "unprognostic (3.91e-2)" "unprognostic (2.61e-2)" "unprognostic (3.41e-2)" "unprognostic (2.55e-1)" "unprognostic (1.46e-3)" "unprognostic (1.85e-1)" "unprognostic (1.46e-1)" "unprognostic (2.40e-1)" "unprognostic (2.71e-1)" 20.9 23.9 27.4 13.3 30.5 28.8 19.8 31.1 32.2 14.3 23.1 18.0 13.6 11.5 21.9 25.2 14.3 15.0 27.8 25.7 28.4 22.6 33.5 15.7 20.3 30.0 28.7 13.7 44.1 19.3 12.6 15.0 30.0 15.9 15.9 4.5 29.8 13.7 31.9 16.9 15.1 17.1 30.3 17.1 23.6 29.2 28.7 19.5 18.3 27.0 17.8 18.2 14.4 33.3 32.1 75.1 29.1 33.3 54.5 71.6 33.4 47.0 61.1 63.3 52.3 50.8 49.6 36.3 45.8 59.4 31.6 52.7 52.0 64.7 57.6 41.6 40.2 26.2 48.0 60.4 46.7 67.2 25.7 54.7 47.5 46.1 52.6 41.9 67.7 34.2 38.5 44.0 57.9 161.2 39.8 36.4 31.2 90.2 74.5 26.2 41.3 47.8 61.5 73.2 30.9 30.2 36.6 60.0 33.6 25.7 71.3 31.5 47.3 36.1 22.0 108.7 42.1 84.9 70.9 63.3 60.4 42.5 41.9 46.1 58.3 55.0 37.5 58.4 34.4 44.1 33.4 35.1 54.3 37.6 31.9 31.5 49.8 38.0 50.8 50.7 41.6 46.4 27.4 30.5 31.1 32.2 25.7 28.4 30.0 28.7 30.0 30.3 28.7 33.3 27.5 28.9 16.2 3.3 19.1 14.0 26.0 37.5 14.2 18.2 25.2 28.1 39.7 15.7 29.0 20.2 12.5 48.5 18.4 19.1 56.7 39.6 59.4 15.4 24.9 28.8 19.7 29.5 4.1 45.2 53.7 27.8 16.3 16.7 19.6 25.8 28.5 43.9 59.8 15.2 3.6 27.1 18.3 25.5 22.2 111.2 29.8 28.1 17.8 0.0 65.8 25.2 35.0 4.0 10.0 42.6 21.9 20.3 36.5 25.9 43.9 82.2 19.8 20.1 32.9 18.0 21.4 90.1 16.1 33.6 15.8 37.1 20.5 33.9 32.9 25.4 CISD1 "C10orf70, MDS029, mitoNEET, ZCD1" ENSG00000122873 "CDGSH iron sulfur domain 1" Q9NZ45 10 58269162-58289586 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 82.3" "Cell type enhanced" "Detected in all" "Distal tubular cells: 716.1;Proximal enterocytes: 539.1;Proximal tubular cells: 726.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074383 Supported Supported Mitochondria NA NA 13000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA074383: AB_2686684" "prognostic unfavorable (1.11e-4)" "unprognostic (8.60e-3)" "unprognostic (1.07e-1)" "unprognostic (4.10e-3)" "unprognostic (2.41e-2)" "unprognostic (3.22e-2)" "prognostic unfavorable (4.15e-4)" "unprognostic (1.87e-2)" "unprognostic (2.35e-1)" "unprognostic (7.78e-2)" "unprognostic (1.33e-2)" "unprognostic (7.23e-2)" "unprognostic (1.34e-3)" "unprognostic (4.19e-2)" "unprognostic (7.20e-2)" "unprognostic (8.07e-2)" "prognostic unfavorable (6.69e-4)" 5.2 10.1 10.0 6.3 9.8 0.9 5.9 10.4 13.6 6.6 11.8 9.7 22.7 5.6 3.4 11.2 6.1 7.2 43.0 10.1 12.7 26.4 16.6 4.3 6.1 10.1 9.9 6.8 5.3 82.3 5.8 5.5 11.2 7.6 8.8 8.2 9.9 7.1 46.4 8.4 21.8 8.0 9.5 4.6 7.2 2.8 9.6 6.5 10.1 49.9 5.9 7.8 3.0 8.9 20.5 10.2 8.0 14.6 10.5 11.6 4.7 16.9 19.2 16.4 22.5 24.1 18.8 36.1 13.9 17.5 9.6 12.9 21.7 15.1 14.7 16.2 29.4 9.5 16.4 19.6 11.9 17.0 7.1 14.6 12.1 15.7 23.9 13.9 19.5 17.9 21.2 16.5 11.6 6.8 14.6 18.2 8.5 15.5 31.4 11.0 29.3 19.0 22.1 7.1 25.0 9.0 12.9 34.1 12.4 7.0 22.7 9.0 19.3 7.1 12.8 20.5 20.4 16.6 29.0 27.2 18.9 16.6 7.0 0.0 4.5 0.2 4.3 3.4 5.3 6.3 4.9 5.0 7.6 5.4 5.7 5.7 2.3 5.4 2.3 5.0 6.8 4.2 10.0 9.8 10.4 13.6 10.1 12.7 10.1 9.9 11.2 9.5 9.6 8.9 31.4 60.9 45.7 27.4 33.0 128.7 87.3 309.4 78.0 84.6 46.4 61.1 321.6 97.2 180.2 134.3 43.8 174.8 22.7 71.1 716.1 98.0 240.9 42.8 30.4 61.6 225.4 24.8 47.2 82.1 78.5 52.7 38.2 43.8 34.3 23.0 63.9 249.6 68.6 42.1 53.1 141.9 272.6 37.0 37.9 366.1 42.3 31.0 183.2 21.5 34.0 47.2 44.3 36.7 30.9 83.2 121.9 40.3 31.7 109.1 539.1 726.8 138.6 56.3 32.9 50.1 55.6 159.4 65.6 94.9 114.2 72.7 26.2 65.0 147.3 69.4 CLCN4 "ClC-4, CLC4" ENSG00000073464 "Chloride voltage-gated channel 4" P51793 X 10156975-10237660 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Transport" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 33.3;retina: 37.9;skeletal muscle: 45.0;tongue: 34.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 85.0;Cone photoreceptor cells: 102.2;Excitatory neurons: 45.7;Horizontal cells: 52.2;Inhibitory neurons: 54.0;Oligodendrocytes: 76.5;Rod photoreceptor cells: 42.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive B-cell: 2.6;neutrophil: 2.2" "Group enriched" "Detected in many" 6 "B-cells: 2.6;granulocytes: 2.2" "Cell line enhanced" "Detected in many" "GAMG: 25.3;HEL: 24.3;SCLC-21H: 24.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031313, HPA063637" Enhanced Approved Approved Vesicles NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 54: Non-specific - Microtubule organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 56: Bipolar cells - Visual perception" Vesicles "HPA031313: AB_10601358, HPA063637: AB_2685069" "unprognostic (1.01e-1)" "unprognostic (1.20e-2)" "unprognostic (5.07e-2)" "prognostic unfavorable (2.13e-5)" "unprognostic (2.96e-1)" "unprognostic (3.75e-1)" "unprognostic (1.04e-2)" "unprognostic (3.66e-1)" "unprognostic (1.75e-1)" "unprognostic (5.99e-2)" "prognostic favorable (9.55e-4)" "unprognostic (9.70e-2)" "unprognostic (9.78e-3)" "unprognostic (1.68e-1)" "unprognostic (1.49e-1)" "unprognostic (1.32e-1)" "unprognostic (1.74e-1)" 2.6 2.7 16.2 1.5 27.4 1.8 1.1 28.8 23.1 1.3 5.2 0.9 0.8 0.6 22.6 1.7 2.9 2.1 12.3 19.6 19.7 2.8 3.2 3.0 2.8 27.1 24.1 1.6 2.2 10.8 5.3 1.1 24.5 1.5 0.7 37.9 2.2 1.0 45.0 1.0 0.7 0.7 18.5 2.6 1.5 1.8 26.8 2.6 6.5 34.2 1.8 1.2 0.7 33.3 5.9 4.6 2.7 0.0 1.5 2.5 0.1 0.2 0.0 0.0 0.0 9.1 4.6 5.0 13.0 1.5 25.3 1.4 1.4 2.9 0.2 0.1 5.7 24.3 2.2 3.5 7.3 0.0 0.1 12.9 3.4 7.0 1.5 4.7 9.4 0.0 1.5 0.1 3.3 1.1 0.0 0.2 4.0 7.1 15.3 0.0 4.5 0.0 2.1 0.8 24.1 8.7 8.6 1.1 0.0 2.7 1.7 2.7 7.4 3.1 5.8 15.3 0.6 0.5 12.1 1.8 10.5 0.0 4.5 1.6 0.3 0.0 0.0 0.2 0.0 0.9 0.0 0.0 0.4 2.6 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.3 16.2 27.4 28.8 23.1 19.6 19.7 27.1 24.1 24.5 18.5 26.8 33.3 1.0 9.6 3.1 11.8 4.9 0.5 0.6 2.0 0.0 85.0 1.1 0.4 31.1 8.6 2.2 7.3 102.2 0.2 0.0 0.1 0.0 2.5 0.1 2.6 1.3 3.0 15.0 9.4 45.7 3.6 0.1 4.0 1.1 3.1 1.3 0.7 13.6 5.1 3.1 52.2 54.0 0.6 4.1 4.8 2.3 0.0 0.9 3.4 0.0 15.9 1.0 15.4 0.0 24.6 76.5 4.1 0.1 3.8 0.4 0.8 0.0 2.9 5.3 42.6 0.0 8.7 6.0 0.0 0.5 0.2 0.1 0.3 0.1 2.6 0.3 1.3 CLCNKB hClC-Kb ENSG00000184908 "Chloride voltage-gated channel Kb" P51801 1 16043736-16057308 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Chloride channel, Ion channel, Voltage-gated channel" "Bartter syndrome, Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "kidney: 209.7" "Cell type enhanced" "Detected in some" "Collecting duct cells: 23.9;Distal tubular cells: 58.7;Early spermatids: 24.6;Ionocytes: 116.0;Late spermatids: 104.2" "Cancer enriched" "Detected in some" 9 "renal cancer: 24.9" "Region enriched" "Detected in some" 6 "cerebellum: 7.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 1.6;HeLa: 1.1" HPA057717 Uncertain NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 38: EFO-21 - Unknown function" "Cluster 31: Spermatids - Spermatogenesis" "HPA057717: AB_2683509" "unprognostic (9.05e-4)" "unprognostic (1.72e-1)" "unprognostic (2.41e-2)" "unprognostic (2.68e-3)" "unprognostic (1.44e-2)" "unprognostic (1.58e-1)" "unprognostic (2.10e-4)" "unprognostic (1.87e-1)" "unprognostic (3.61e-2)" "unprognostic (2.31e-1)" "unprognostic (4.57e-2)" "unprognostic (1.02e-1)" "prognostic favorable (1.27e-7)" "unprognostic (2.04e-2)" "unprognostic (4.62e-1)" "unprognostic (1.78e-2)" "unprognostic (5.14e-2)" 0.6 1.7 0.1 0.0 0.3 0.0 0.3 7.0 0.3 0.7 0.6 0.4 0.0 0.9 0.7 0.2 0.4 0.2 4.0 0.1 0.3 209.7 0.0 0.4 0.0 0.4 0.5 1.3 1.1 4.9 2.5 0.3 1.2 0.7 0.3 1.2 48.1 1.5 0.1 0.1 0.1 0.3 0.3 0.1 0.7 2.8 0.5 0.1 16.1 0.1 0.0 0.1 0.4 0.6 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.7 0.0 1.6 0.2 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 7.0 0.3 0.1 0.3 0.4 0.5 1.2 0.3 0.5 0.6 0.0 3.2 0.6 0.0 0.0 0.0 0.1 0.1 0.0 0.8 0.1 0.3 4.2 0.0 1.4 23.9 0.0 0.3 0.0 0.6 58.7 1.0 24.6 0.1 0.0 0.1 1.2 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.1 0.3 116.0 0.0 0.0 104.2 0.9 0.0 0.0 1.0 0.0 1.9 0.0 0.0 0.0 0.0 0.2 1.2 0.0 0.0 0.0 0.4 0.7 0.0 0.0 0.0 0.2 1.6 0.9 0.0 0.0 0.5 0.1 0.0 0.9 0.1 CLDN11 "OSP, OTM" ENSG00000013297 "Claudin 11" O75508 3 170418868-170454733 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 130.1;ovary: 95.4;testis: 116.9" "Cell type enhanced" "Detected in many" "Fibroblasts: 56.4;Leydig cells: 105.3;Oligodendrocytes: 394.5;Peritubular cells: 67.7" "Cancer enhanced" "Detected in many" "glioma: 11.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 141.3;ASC TERT1: 174.2;EFO-21: 91.8;HUVEC TERT2: 162.2;TIME: 252.1" "Region enriched" "Detected in all" 5 "white matter: 2084.8" "CAB009789, HPA013166, HPA013657" Enhanced Supported "Lipid droplets,Cell Junctions" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 33: Fibroblasts - ECM organization" "Cell Junctions" "Lipid droplets" "CAB009789: AB_639330, HPA013166: AB_1854821, HPA013657: " "prognostic favorable (6.31e-4)" "unprognostic (3.18e-1)" "unprognostic (2.32e-2)" "unprognostic (5.28e-4)" "unprognostic (3.45e-2)" "unprognostic (4.60e-1)" "unprognostic (5.25e-2)" "unprognostic (5.40e-2)" "unprognostic (2.52e-1)" "unprognostic (1.40e-1)" "unprognostic (1.03e-1)" "unprognostic (5.48e-2)" "unprognostic (8.70e-11)" "unprognostic (2.50e-3)" "unprognostic (1.93e-1)" "unprognostic (6.68e-3)" "unprognostic (2.29e-1)" 29.9 5.4 18.8 0.0 51.7 0.0 15.3 48.7 36.5 6.7 4.4 7.6 0.1 8.1 1.5 5.1 18.0 8.7 7.8 22.7 34.6 6.4 2.2 4.8 0.2 130.1 44.2 95.4 0.8 0.0 20.9 1.2 88.6 11.2 0.3 0.2 5.2 1.0 1.5 6.5 6.6 0.4 52.5 1.2 3.1 116.9 47.4 0.0 1.8 0.7 0.1 13.2 13.2 94.6 0.0 0.0 0.1 0.0 141.3 174.2 0.0 1.2 8.5 11.0 19.6 0.0 19.2 0.0 91.8 14.2 0.0 0.0 0.0 0.0 21.9 0.0 0.0 0.0 0.0 10.6 42.8 0.0 0.0 61.0 0.0 60.9 0.0 0.4 162.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.9 0.0 4.6 0.0 0.0 0.0 0.0 0.0 9.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 252.1 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.8 51.7 48.7 36.5 22.7 34.6 130.1 44.2 88.6 52.5 47.4 94.6 16.4 0.0 0.6 2.3 0.4 14.4 15.6 1.0 0.0 0.5 5.7 27.7 1.4 1.5 0.1 1.8 0.0 0.9 0.8 0.3 0.0 0.1 8.3 0.5 0.2 37.3 0.0 2.7 1.5 0.0 1.6 56.4 0.0 0.6 0.0 27.2 49.2 1.1 0.9 0.0 2.8 0.0 0.0 1.2 23.8 24.3 105.3 1.1 14.2 24.4 0.0 0.4 0.0 3.5 394.5 0.7 0.0 67.7 0.0 15.4 0.2 0.2 0.2 0.1 0.0 2.9 6.6 11.6 4.1 1.0 10.2 0.8 0.6 1.6 0.1 2.0 CLDN18 SFTPJ ENSG00000066405 "Claudin 18" P56856 3 137998735-138033655 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 50 "lung: 252.2;stomach 1: 724.9" "Group enriched" "Detected in some" 53 "Alveolar cells type 1: 1602.5;Alveolar cells type 2: 431.2;Gastric mucus-secreting cells: 1153.4;Pancreatic endocrine cells: 442.5" "Group enriched" "Detected in some" 11 "pancreatic cancer: 113.6;stomach cancer: 186.8" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 19 "OE19: 15.1" "Not detected" "Not detected" "Not detected" "Not detected" "CAB013010, CAB013243, HPA018446" Enhanced Approved "Cell Junctions" NA NA "Cluster 4: Stomach - Digestion" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Cell Junctions" "CAB013010: AB_2533382, CAB013243: AB_2533383, HPA018446: AB_2669866" "unprognostic (1.03e-1)" "unprognostic (1.49e-1)" "unprognostic (2.93e-1)" "unprognostic (1.04e-2)" "unprognostic (1.41e-1)" "unprognostic (8.51e-2)" "unprognostic (5.14e-4)" "unprognostic (2.00e-1)" "unprognostic (1.29e-1)" "unprognostic (2.60e-1)" "unprognostic (9.54e-2)" "unprognostic (1.38e-2)" "unprognostic (4.42e-5)" "unprognostic (1.66e-1)" "unprognostic (2.26e-1)" "unprognostic (8.26e-2)" "unprognostic (2.95e-1)" 0.3 0.3 0.3 0.4 0.4 0.1 0.2 1.0 0.5 0.4 2.2 0.7 1.5 0.2 0.5 0.6 0.5 3.3 9.7 0.3 0.2 0.2 0.1 252.2 0.0 0.9 0.9 0.5 0.8 0.0 0.5 0.3 0.5 0.2 0.2 0.7 0.3 0.4 0.1 1.1 0.8 0.1 0.7 0.5 724.9 1.3 0.5 0.1 0.1 0.0 0.7 0.2 0.3 0.2 0.1 0.0 0.2 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.4 0.0 0.2 0.1 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.7 0.2 0.1 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.1 0.5 15.1 0.1 0.3 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.2 0.4 0.3 0.1 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 1.0 0.5 0.3 0.2 0.9 0.9 0.5 0.7 0.5 0.2 0.0 1602.5 431.2 1.0 0.9 0.0 0.0 0.0 0.0 1.1 0.0 0.0 17.0 0.0 11.2 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.6 0.3 0.2 0.6 0.0 0.0 0.5 11.4 0.0 1.4 1153.4 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.7 0.0 2.0 0.0 1.9 0.0 0.1 0.0 0.0 0.2 442.5 0.0 0.0 1.3 0.0 0.0 0.1 0.7 1.3 0.0 0.9 0.1 15.3 11.9 0.0 0.0 0.0 1.3 0.0 0.0 0.1 CLDN3 "C7orf1, CPE-R2, CPETR2, HRVP1, RVP1" ENSG00000165215 "Claudin 3" O15551 7 73768997-73770270 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cancer-related genes, Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 263.1;thyroid gland: 116.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 1839.9;Endometrial ciliated cells: 1221.7;Glandular and luminal cells: 1555.7;Intestinal goblet cells: 1471.3;Paneth cells: 2326.0;Proximal enterocytes: 3162.1;Undifferentiated cells: 1266.0" "Cancer enhanced" "Detected in many" "ovarian cancer: 529.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MCF7: 230.7;PC-3: 47.6;RPMI-8226: 40.5;SCLC-21H: 58.0;T-47d: 105.4" "Region enhanced" "Detected in single" "basal ganglia: 1.5" "Region enhanced" "Detected in many" "midbrain: 9.7" HPA014361 Enhanced Supported "Cell Junctions" NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 44: Endometrium - Transcription" "Cell Junctions" "HPA014361: AB_2668982" "unprognostic (1.84e-1)" "unprognostic (4.83e-2)" "unprognostic (2.05e-1)" "unprognostic (5.27e-2)" "unprognostic (2.61e-1)" "unprognostic (1.31e-1)" "unprognostic (2.79e-2)" "unprognostic (8.26e-2)" "unprognostic (3.11e-1)" "unprognostic (1.46e-1)" "unprognostic (2.28e-3)" "unprognostic (1.42e-1)" "prognostic favorable (3.39e-5)" "unprognostic (1.46e-2)" "unprognostic (1.87e-1)" "unprognostic (5.18e-2)" "unprognostic (6.72e-2)" 0.7 0.2 0.2 7.8 0.3 0.2 26.7 4.2 0.3 12.3 37.6 263.1 54.4 7.5 1.4 1.3 29.6 2.2 0.1 1.1 1.2 46.5 40.4 10.7 0.2 1.3 1.9 0.5 96.6 1.5 27.7 1.0 0.6 58.3 17.5 0.4 72.9 8.3 0.1 9.6 169.5 0.8 0.5 0.2 1.4 0.7 0.9 1.0 116.3 0.0 1.2 1.5 0.2 0.2 2.5 3.6 0.0 0.4 0.0 0.0 17.8 0.0 0.0 0.0 0.0 4.2 35.7 0.0 9.9 0.0 0.0 1.0 0.4 0.0 0.0 0.1 4.9 0.0 0.8 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 230.7 0.4 1.2 2.1 9.1 47.6 0.1 0.0 40.5 2.1 0.2 58.0 0.7 0.0 33.6 0.0 0.2 105.4 0.0 0.2 0.2 0.6 0.9 0.1 0.2 0.6 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 4.2 0.3 1.1 1.2 1.3 1.9 0.6 0.5 0.9 0.2 1.6 38.5 37.8 0.0 13.2 0.1 60.3 43.7 0.0 0.7 289.9 182.5 0.6 287.4 86.3 126.9 4.2 63.9 5.1 1839.9 9.8 297.5 0.0 1221.7 130.5 10.3 606.1 5.3 0.0 19.1 17.7 4.1 16.8 1555.7 28.0 1.5 0.4 40.5 5.1 0.0 0.0 1471.3 116.0 0.3 0.0 0.3 2.5 9.9 10.6 0.0 2.0 11.8 0.0 0.0 0.0 36.7 2326.0 0.0 4.4 433.2 3162.1 58.6 498.4 10.6 0.0 0.0 20.3 0.1 0.3 2.7 0.0 72.4 17.5 0.0 1266.0 607.3 CLDN5 "AWAL, BEC1, CPETRL1, TMVCF" ENSG00000184113 "Claudin 5" O00501 22 19523024-19527545 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 439.7;breast: 420.9;lung: 398.7" "Group enriched" "Detected in many" 10 "Adipocytes: 2644.3;Endothelial cells: 775.2;Hepatic stellate cells: 701.4" "Cancer enriched" "Detected in all" 4 "glioma: 32.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 18.8" "Lineage enriched" "Detected in many" 4 "granulocytes: 18.8" "Group enriched" "Detected in some" 10 "HUVEC TERT2: 85.4;SCLC-21H: 53.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB002607 Approved NA NA "Cluster 34: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB002607: " "unprognostic (1.26e-1)" "unprognostic (2.05e-3)" "unprognostic (1.77e-2)" "unprognostic (2.07e-1)" "unprognostic (3.05e-3)" "unprognostic (6.00e-2)" "unprognostic (4.98e-2)" "unprognostic (3.24e-3)" "unprognostic (1.33e-1)" "unprognostic (8.95e-2)" "unprognostic (2.29e-3)" "unprognostic (1.15e-1)" "unprognostic (7.31e-2)" "unprognostic (2.01e-2)" "unprognostic (2.47e-2)" "unprognostic (2.22e-1)" "unprognostic (2.96e-2)" 439.7 16.2 124.1 6.1 101.0 0.3 420.9 111.7 127.4 70.2 205.2 75.9 9.2 86.1 3.0 54.4 83.1 6.5 138.3 93.8 103.3 45.5 16.9 398.7 9.6 124.5 114.0 36.4 20.7 1.5 16.9 12.5 127.8 50.2 3.6 2.0 36.0 3.5 101.6 95.9 71.0 6.4 109.2 44.8 41.4 10.5 160.7 1.8 122.5 14.9 2.2 103.7 75.9 107.4 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.0 0.1 0.3 0.1 0.1 0.2 1.1 0.0 0.0 0.0 0.0 85.4 0.1 0.7 0.2 0.1 0.0 0.1 0.5 0.2 0.0 0.2 0.9 0.7 0.1 0.0 0.0 53.0 0.3 0.0 0.0 0.0 0.0 0.4 0.2 7.1 0.1 1.1 0.3 0.0 0.1 0.0 0.2 0.0 0.0 0.2 18.8 0.4 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.3 0.2 4.6 0.2 5.8 0.0 0.1 0.1 0.0 26.9 124.1 101.0 111.7 127.4 93.8 103.3 124.5 114.0 127.8 109.2 160.7 107.4 2644.3 3.2 7.7 0.7 2.4 32.4 1.1 0.1 3.4 1.8 5.9 7.6 14.8 2.8 0.6 7.3 0.0 0.3 4.2 0.0 0.0 0.7 5.0 8.1 0.7 775.2 2.4 8.0 0.0 0.8 0.1 12.5 0.0 1.0 1.3 0.3 701.4 2.7 0.8 0.0 0.1 0.2 4.1 17.0 33.3 5.5 5.3 46.2 14.2 129.3 0.7 2.4 1.0 0.5 0.3 0.0 0.0 0.7 2.8 4.0 0.0 0.0 0.3 7.3 0.0 61.7 12.1 1.1 1.9 1.2 30.5 0.0 4.6 25.0 0.0 6.7 CLDND1 "C3orf4, Z38" ENSG00000080822 "Claudin domain containing 1" Q9NY35 3 98497912-98523066 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "brain: 1093.8;choroid plexus: 316.7" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 575.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029841 Approved Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 70: Brain - Nervous system development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 59: Non-specific - Transcription" Nucleoplasm "Nucleoli, Cytosol" "HPA029841: AB_10600658" "unprognostic (1.64e-1)" "unprognostic (3.63e-1)" "unprognostic (3.13e-2)" "unprognostic (8.50e-2)" "unprognostic (9.15e-2)" "unprognostic (7.30e-2)" "unprognostic (2.43e-3)" "unprognostic (4.08e-2)" "unprognostic (3.65e-2)" "unprognostic (8.30e-3)" "unprognostic (1.21e-1)" "unprognostic (3.14e-1)" "prognostic unfavorable (5.84e-6)" "unprognostic (5.73e-3)" "unprognostic (6.54e-2)" "unprognostic (3.05e-1)" "unprognostic (1.51e-1)" 53.6 42.6 477.0 40.7 757.5 49.1 48.8 696.1 804.5 59.0 316.7 58.3 36.5 58.8 43.1 77.8 46.7 50.6 57.6 483.5 577.6 39.2 50.0 46.9 54.7 851.3 670.8 63.9 23.6 32.6 28.2 73.8 837.8 49.5 46.9 46.5 29.8 51.9 43.6 64.8 42.2 63.5 643.7 44.0 37.4 106.6 638.3 44.7 40.5 68.9 54.9 64.0 65.8 1093.8 67.3 26.2 83.2 50.7 96.0 75.0 44.6 52.0 69.8 71.0 97.8 52.7 66.9 33.7 69.1 49.4 134.3 90.4 61.6 39.9 124.3 79.3 27.5 68.3 18.6 48.1 76.2 62.7 67.3 88.4 207.6 54.0 58.7 77.6 79.1 64.7 35.4 100.6 102.9 33.4 47.8 42.8 75.1 28.7 55.9 31.9 110.6 43.4 67.7 30.0 30.1 82.6 74.6 24.4 108.5 110.5 24.5 52.8 75.1 94.6 86.2 65.3 69.3 130.8 59.8 53.9 154.9 61.0 125.2 179.8 91.0 103.9 102.1 55.4 193.5 101.5 190.3 187.1 98.9 99.3 76.6 78.1 70.2 274.0 56.7 63.9 399.7 155.1 477.0 757.5 696.1 804.5 483.5 577.6 851.3 670.8 837.8 643.7 638.3 1093.8 83.3 35.3 36.6 17.9 72.1 144.0 131.7 122.3 87.0 20.1 43.6 45.3 53.8 17.2 71.4 27.6 25.0 52.0 72.8 16.9 29.4 21.2 105.3 21.1 47.7 70.8 28.7 65.4 25.1 16.2 160.6 86.6 30.1 41.7 36.8 25.2 61.4 19.4 35.6 15.2 23.6 19.6 89.5 29.2 168.1 76.7 51.6 46.9 113.8 20.6 42.3 28.1 38.1 30.7 575.2 30.3 16.8 46.6 131.7 98.1 34.6 23.3 27.5 35.0 52.6 53.2 128.4 182.4 55.3 90.1 196.5 95.8 147.1 22.8 17.5 121.9 CLEC14A C14orf27 ENSG00000176435 "C-type lectin domain containing 14A" Q86T13 14 38254000-38256093 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 13 "Adipocytes: 396.6;Endothelial cells: 272.8;Hepatic stellate cells: 567.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 83.7;HUVEC TERT2: 451.8;TIME: 158.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039468, HPA048119" Uncertain Supported "Endoplasmic reticulum,Golgi apparatus" NA NA 4100000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Endoplasmic reticulum, Golgi apparatus" "HPA039468: AB_2676524, HPA048119: AB_2680270" "unprognostic (4.02e-1)" "unprognostic (4.26e-2)" "unprognostic (4.20e-3)" "unprognostic (9.44e-2)" "unprognostic (1.35e-1)" "prognostic favorable (4.13e-6)" "unprognostic (2.55e-3)" "unprognostic (2.69e-1)" "unprognostic (1.67e-1)" "unprognostic (6.90e-2)" "unprognostic (5.41e-2)" "unprognostic (1.26e-1)" "unprognostic (1.63e-2)" "unprognostic (1.75e-2)" "unprognostic (1.55e-1)" "unprognostic (4.97e-2)" "unprognostic (5.28e-2)" 67.1 9.5 13.6 7.9 13.4 0.1 50.6 13.8 15.2 24.8 10.9 15.2 10.1 31.2 7.6 11.1 22.6 19.0 65.1 11.5 13.3 15.9 9.4 55.5 6.6 15.0 13.9 9.5 7.8 10.5 6.1 25.0 15.4 14.5 7.2 0.8 13.6 9.8 33.2 15.8 18.8 19.8 13.1 16.7 13.8 3.5 14.9 4.6 31.4 43.3 4.2 19.2 16.8 15.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 83.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 451.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 158.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.6 13.4 13.8 15.2 11.5 13.3 15.0 13.9 15.4 13.1 14.9 15.6 396.6 0.0 3.2 0.0 0.9 3.4 0.2 0.0 1.8 0.1 1.5 2.5 6.4 1.5 0.6 0.0 0.0 0.1 0.2 0.0 0.0 0.1 1.1 0.2 0.5 272.8 0.0 0.0 0.4 0.2 0.1 31.0 0.0 0.3 1.3 0.1 567.2 2.1 0.4 0.0 0.2 0.0 0.0 6.4 3.1 1.0 0.6 1.1 5.4 15.0 0.0 0.2 0.0 4.0 2.9 0.0 0.0 0.4 1.4 0.2 0.0 0.0 0.0 0.5 0.0 14.1 7.5 1.6 0.9 0.9 3.1 0.1 1.3 6.7 0.0 0.3 CLEC17A FLJ45910 ENSG00000187912 "C-type lectin domain containing 17A" Q6ZS10 19 14583084-14612035 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "intestine: 6.6;lymphoid tissue: 18.2" "Group enriched" "Detected in some" 4 "B-cells: 20.7;Early spermatids: 5.3;Late spermatids: 12.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 11 "memory B-cell: 21.5;naive B-cell: 43.1" "Lineage enriched" "Detected in many" 14 "B-cells: 43.1" "Group enriched" "Detected in some" 5 "Daudi: 5.7;U-698: 9.9" "Not detected" "Not detected" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "unprognostic (4.71e-5)" "unprognostic (1.34e-2)" "unprognostic (9.64e-4)" "unprognostic (5.02e-3)" "unprognostic (3.90e-1)" "unprognostic (9.00e-4)" "unprognostic (3.18e-3)" "unprognostic (1.60e-3)" "unprognostic (1.32e-2)" "unprognostic (7.11e-2)" "unprognostic (3.78e-2)" "unprognostic (4.43e-2)" "unprognostic (9.13e-3)" "unprognostic (1.65e-1)" "unprognostic (5.91e-2)" "unprognostic (2.07e-1)" "unprognostic (1.23e-1)" 0.3 0.2 0.7 8.2 0.7 2.2 0.1 1.6 0.9 0.0 0.9 0.5 0.5 0.3 0.2 0.2 0.2 0.6 0.2 0.7 0.9 0.2 0.2 0.2 16.1 1.3 0.9 0.2 0.0 0.1 0.1 0.2 1.2 0.3 0.6 0.4 0.6 0.1 0.3 0.5 6.6 0.1 0.9 11.4 0.7 0.9 0.8 1.4 0.2 0.1 18.2 0.9 0.0 1.5 0.1 0.0 0.1 0.2 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.1 0.1 5.7 0.0 0.0 0.9 0.2 0.0 0.0 0.1 0.3 0.1 0.1 0.4 0.1 0.0 0.2 1.1 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.1 0.4 0.0 0.2 0.1 1.4 0.1 0.1 0.1 0.1 0.2 0.1 0.0 0.2 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.2 0.2 0.2 0.3 0.1 0.3 0.1 9.9 0.3 0.1 0.1 0.7 0.7 0.3 0.2 0.4 0.2 21.5 0.1 0.1 3.0 43.1 0.2 0.2 2.7 0.4 0.3 0.5 0.1 2.2 0.7 0.7 1.6 0.9 0.7 0.9 1.3 0.9 1.2 0.9 0.8 1.5 0.0 0.0 0.0 1.3 20.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 12.7 0.0 0.8 0.0 2.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CLEC7A "CD369, CLECSF12, dectin-1, hDectin-1, SCARE2" ENSG00000172243 "C-type lectin domain containing 7A" Q9BXN2 12 10116777-10130258 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "bone marrow: 84.0;lung: 30.9;lymphoid tissue: 44.5" "Cell type enhanced" "Detected in many" "Hofbauer cells: 87.2;Kupffer cells: 415.2;Langerhans cells: 291.5;Macrophages: 255.5;monocytes: 186.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 249.6" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 16 "Karpas-707: 192.2;U-266/84: 168.1" "Low region specificity" "Detected in all" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" "unprognostic (1.79e-1)" "unprognostic (1.88e-2)" "unprognostic (2.98e-2)" "unprognostic (3.64e-1)" "unprognostic (3.03e-2)" "unprognostic (5.49e-2)" "unprognostic (5.19e-2)" "unprognostic (5.88e-3)" "unprognostic (2.10e-1)" "unprognostic (9.87e-2)" "unprognostic (7.46e-2)" "unprognostic (4.40e-1)" "prognostic unfavorable (1.31e-4)" "unprognostic (1.83e-2)" "unprognostic (3.89e-2)" "unprognostic (5.13e-2)" "unprognostic (1.14e-1)" 9.9 5.9 2.2 44.5 2.0 84.0 4.5 2.6 3.7 3.5 3.3 7.5 5.6 3.2 3.7 9.7 5.8 11.1 5.7 1.9 3.3 3.5 11.0 30.9 14.4 5.0 2.7 2.4 2.9 2.0 2.7 7.3 4.0 3.3 7.3 1.7 7.3 3.2 1.3 3.8 8.6 8.7 3.6 34.2 4.6 1.5 3.8 10.0 2.6 2.0 11.9 9.1 4.8 6.1 0.3 0.4 0.1 0.2 0.0 0.0 1.1 0.0 0.5 0.2 0.1 0.1 0.4 0.1 0.1 0.0 1.1 0.6 0.0 0.0 0.0 0.1 0.0 0.4 0.5 0.0 0.0 0.9 0.7 0.1 0.8 0.1 0.0 0.2 0.1 0.2 0.0 192.2 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.1 4.3 0.0 5.2 0.3 0.2 0.3 0.6 0.0 1.4 0.4 0.1 0.3 0.1 0.2 0.2 0.2 11.4 168.1 0.1 0.3 1.0 0.2 1.4 122.9 2.2 0.3 137.2 0.5 0.3 0.3 0.2 60.6 0.3 0.3 0.2 249.6 0.4 148.1 1.0 0.4 40.4 2.2 2.0 2.6 3.7 1.9 3.3 5.0 2.7 4.0 3.6 3.8 6.1 2.0 12.8 15.1 0.3 5.9 3.7 0.2 0.9 8.6 0.0 3.1 2.8 0.9 0.0 9.7 0.0 0.0 1.5 2.1 0.2 0.0 0.1 1.7 0.2 0.1 9.3 0.0 0.0 0.1 0.0 14.1 2.4 0.0 0.1 6.3 0.0 6.1 2.1 87.2 0.0 0.1 0.0 4.1 415.2 291.5 2.2 0.3 255.5 3.6 27.2 186.1 0.0 8.2 0.0 0.0 0.0 1.1 0.0 1.1 0.1 0.0 1.3 2.4 0.4 13.1 1.1 1.0 0.1 0.5 13.2 3.0 5.3 4.1 0.0 0.0 0.5 CLHC1 "C2orf63, FLJ31438" ENSG00000162994 "Clathrin heavy chain linker domain containing 1" Q8NHS4 2 55172547-55232563 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 35.6;Early spermatids: 52.6;Late spermatids: 40.1;Oligodendrocyte precursor cells: 48.2;Oligodendrocytes: 40.2;Respiratory ciliated cells: 44.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA045418, HPA053557" Uncertain Approved "Nucleoli fibrillar center,Centrosome" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 20: HeLa - Mitochondria" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoli fibrillar center, Centrosome" "HPA045418: AB_10962144, HPA053557: AB_2682188" "unprognostic (1.60e-1)" "unprognostic (2.86e-1)" "unprognostic (3.43e-2)" "unprognostic (7.65e-3)" "unprognostic (1.09e-1)" "unprognostic (1.68e-2)" "unprognostic (4.91e-2)" "unprognostic (6.41e-3)" "unprognostic (1.03e-3)" "unprognostic (1.39e-1)" "unprognostic (3.54e-4)" "unprognostic (6.36e-2)" "unprognostic (1.05e-4)" "unprognostic (1.84e-1)" "unprognostic (1.47e-1)" "unprognostic (1.19e-2)" "prognostic favorable (2.15e-4)" 2.3 2.8 2.7 1.8 3.2 2.1 3.3 6.7 3.8 3.2 11.4 2.8 2.1 4.2 5.0 2.6 4.4 3.1 2.4 3.2 2.7 3.6 1.6 2.5 2.8 4.9 5.5 3.2 2.6 5.4 5.9 3.6 3.1 4.5 3.1 7.7 2.7 3.5 1.7 4.9 2.7 3.5 3.4 3.4 2.4 15.1 3.0 4.1 3.9 1.0 2.1 2.9 2.9 4.5 3.4 2.2 6.6 3.4 2.4 3.3 5.1 4.2 3.9 2.1 1.9 4.5 2.8 4.7 2.6 1.9 2.7 5.3 2.8 3.7 4.3 4.3 3.6 7.1 7.9 4.5 2.8 4.4 3.5 4.3 3.0 2.8 6.0 6.6 2.2 4.3 3.8 2.9 2.4 2.5 3.9 4.6 2.3 1.2 1.0 3.8 3.3 3.0 3.5 4.2 6.4 4.4 2.8 4.0 4.7 4.7 2.8 2.4 5.8 5.2 3.4 2.7 3.5 5.4 1.5 2.6 4.3 4.4 1.4 0.5 0.2 1.3 0.3 0.6 0.0 0.4 0.5 0.3 0.4 0.4 0.6 0.3 0.1 0.9 0.5 0.9 0.4 0.3 2.7 3.2 6.7 3.8 3.2 2.7 4.9 5.5 3.1 3.4 3.0 4.5 3.0 0.0 4.1 35.6 2.7 1.9 5.2 7.0 4.0 12.3 3.9 3.8 4.7 1.5 9.8 3.7 16.7 3.4 1.0 2.1 5.9 3.8 52.6 19.3 7.1 3.0 7.3 2.1 18.8 1.4 1.7 5.1 3.6 4.3 0.0 13.5 5.0 0.3 2.3 10.1 27.0 1.7 4.1 4.6 0.7 40.1 4.1 3.1 1.8 15.0 2.0 9.6 2.1 48.2 40.2 1.0 1.2 5.7 1.6 3.9 1.8 3.0 44.9 19.7 0.0 3.8 3.7 29.9 2.3 3.5 2.3 3.4 2.2 7.6 2.9 4.1 CLMN "FLJ12383, KIAA0500, KIAA1188" ENSG00000165959 Calmin Q96JQ2 14 95181940-95319908 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 67.0" "Cell type enhanced" "Detected in many" "Early spermatids: 161.8;Late spermatids: 313.5;Oligodendrocytes: 418.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "GAMG: 13.8;SK-BR-3: 16.0;T-47d: 13.5;WM-115: 15.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012634 Enhanced Approved "Nuclear bodies,Cytosol" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nuclear bodies" Cytosol "HPA012634: AB_1846973" "unprognostic (5.31e-2)" "unprognostic (2.12e-1)" "unprognostic (4.20e-2)" "unprognostic (6.07e-2)" "unprognostic (8.88e-2)" "unprognostic (4.31e-1)" "unprognostic (4.18e-2)" "unprognostic (7.24e-2)" "unprognostic (8.31e-2)" "unprognostic (2.64e-1)" "unprognostic (1.29e-3)" "unprognostic (3.09e-2)" "prognostic favorable (2.68e-7)" "unprognostic (8.27e-2)" "unprognostic (1.33e-1)" "unprognostic (1.45e-2)" "unprognostic (9.91e-3)" 11.1 1.1 16.6 4.2 38.9 1.1 10.9 11.4 28.1 7.5 6.9 11.5 3.0 4.9 7.4 2.9 9.2 5.8 5.3 15.5 12.2 13.3 14.1 4.9 1.3 21.5 25.7 2.9 17.3 1.7 2.9 2.3 23.3 6.9 12.8 9.8 9.2 5.0 3.8 3.2 6.7 2.8 7.3 3.0 7.2 32.8 42.9 1.0 5.9 5.5 1.6 4.7 6.9 67.0 6.3 8.4 1.3 0.2 4.9 2.2 0.5 0.1 0.0 0.4 0.3 0.7 10.5 0.0 0.9 0.0 13.8 5.5 0.6 3.7 0.0 4.3 1.5 0.2 0.3 5.0 0.5 0.0 0.1 2.4 3.6 1.6 5.8 1.9 4.2 2.3 0.0 1.2 3.0 5.6 0.3 0.5 0.5 7.7 2.0 4.8 4.4 2.8 3.9 10.3 1.7 1.6 2.1 16.0 8.2 1.2 13.5 0.4 1.2 0.1 3.6 0.0 0.3 1.6 0.1 5.8 2.9 2.5 15.5 7.3 6.9 0.6 0.0 2.4 0.0 3.0 0.0 0.0 1.4 1.5 0.0 0.1 5.7 0.0 1.5 2.4 0.0 2.1 16.6 38.9 11.4 28.1 15.5 12.2 21.5 25.7 23.3 7.3 42.9 67.0 12.9 16.0 3.4 21.9 18.0 6.2 39.2 11.7 37.0 61.8 39.0 22.2 58.6 42.9 17.3 58.8 14.6 2.5 3.5 93.1 27.4 53.1 161.8 76.7 16.9 11.4 23.4 0.4 9.3 47.5 1.8 12.2 33.6 37.3 4.5 0.4 2.2 81.9 7.3 38.7 11.5 72.5 8.2 11.9 7.2 313.5 22.4 15.6 3.6 1.0 17.1 3.5 0.0 5.0 418.6 40.1 44.1 10.9 21.9 62.3 15.9 21.0 115.6 28.2 105.2 4.8 100.6 4.2 15.3 7.1 2.6 2.9 2.8 0.2 50.2 51.5 CLPB "ANKCLB, FLJ13152, HSP78, SKD3" ENSG00000162129 "Caseinolytic mitochondrial matrix peptidase chaperone subunit B" Q9H078 11 72285495-72434680 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Hydrolase "Cataract, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "testis: 144.6" "Cell type enriched" "Detected in many" 4 "Late spermatids: 5136.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 25.5" "Group enriched" "Detected in all" 5 "dendritic cells: 25.5;granulocytes: 7.7;monocytes: 15.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039005, HPA039006, HPA064571" Enhanced NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 83: Testis - Spermatogenesis" "Cluster 39: CACO-2 - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" "HPA039005: AB_2676305, HPA039006: AB_10672767, HPA064571: AB_2685290" "unprognostic (9.36e-2)" "unprognostic (1.06e-2)" "unprognostic (2.51e-1)" "unprognostic (1.23e-1)" "unprognostic (2.99e-1)" "unprognostic (2.05e-2)" "unprognostic (8.22e-2)" "unprognostic (8.37e-2)" "unprognostic (2.61e-1)" "unprognostic (1.02e-1)" "unprognostic (1.01e-2)" "unprognostic (1.18e-1)" "prognostic favorable (8.36e-8)" "unprognostic (9.29e-2)" "unprognostic (1.25e-1)" "unprognostic (5.83e-2)" "unprognostic (3.28e-2)" 6.0 7.2 3.2 6.6 4.2 11.7 3.5 6.3 7.7 2.9 0.4 3.7 3.9 3.4 2.0 4.0 3.2 3.0 6.2 3.9 6.2 9.0 11.2 3.5 3.7 7.6 5.0 2.9 5.9 9.3 2.2 6.1 8.6 2.3 3.4 6.7 5.9 3.8 8.8 2.4 2.6 6.4 5.0 3.9 3.8 144.6 6.6 4.0 5.7 7.2 3.3 3.8 2.6 5.2 12.7 39.4 9.5 20.5 12.2 9.8 28.8 12.9 8.9 21.8 15.5 55.5 19.1 28.6 30.5 13.0 35.0 26.5 30.6 31.0 23.0 26.3 24.0 23.5 38.3 28.4 10.1 28.0 45.3 14.6 7.7 37.7 33.2 6.4 23.3 26.9 39.7 20.3 12.7 33.0 26.7 23.3 10.5 40.4 35.4 22.2 16.6 14.3 9.9 22.6 27.7 16.9 16.8 39.9 30.8 11.5 22.4 22.0 16.9 29.0 18.0 27.4 25.9 9.9 16.6 18.4 14.6 22.2 19.5 7.7 15.7 0.8 3.0 13.5 3.1 1.9 1.6 2.8 25.5 1.8 2.1 1.8 1.1 2.6 7.8 4.3 1.1 7.8 3.2 4.2 6.3 7.7 3.9 6.2 7.6 5.0 8.6 5.0 6.6 5.2 9.0 16.0 9.7 4.6 6.1 0.4 5.3 5.9 2.2 4.1 7.7 5.0 3.7 2.8 8.6 9.2 4.2 13.0 3.2 3.9 5.9 13.7 1135.5 7.2 13.4 8.0 0.0 11.4 9.8 16.3 17.1 5.5 7.1 9.7 3.8 9.2 1.4 10.7 21.6 3.3 9.8 1.8 10.2 5.9 4.2 5136.8 25.1 13.2 1.8 14.0 8.8 1.9 2.1 11.1 10.4 10.4 1.4 18.4 14.2 6.3 4.3 24.3 5.3 5.5 13.1 3.5 8.1 40.9 22.9 6.0 1.1 33.1 3.6 16.7 2.6 6.6 CLSPN ENSG00000092853 Claspin Q9HAW4 1 35720218-35769978 "Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 11.3;lymphoid tissue: 7.9;retina: 6.8;testis: 5.7" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 101.0;Spermatocytes: 281.1;Spermatogonia: 263.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Region enriched" "Detected in some" 6 "basal ganglia: 7.8" "Low region specificity" "Detected in many" "HPA026305, HPA026312" Enhanced "Nucleoplasm,Golgi apparatus" Yes Yes "Cluster 17: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoplasm, Golgi apparatus" "HPA026305: AB_2671833, HPA026312: AB_2671837" "unprognostic (4.75e-2)" "unprognostic (1.01e-1)" "unprognostic (9.64e-3)" "unprognostic (3.54e-2)" "unprognostic (6.82e-2)" "unprognostic (1.62e-2)" "unprognostic (1.18e-6)" "unprognostic (3.99e-3)" "unprognostic (2.08e-3)" "unprognostic (1.63e-2)" "unprognostic (8.71e-6)" "unprognostic (3.23e-2)" "unprognostic (7.61e-6)" "prognostic favorable (4.92e-4)" "unprognostic (5.12e-1)" "unprognostic (1.73e-1)" "unprognostic (1.29e-1)" 0.5 0.2 0.7 3.2 0.6 11.3 0.5 0.6 1.4 0.2 0.4 1.4 1.0 0.4 0.7 0.9 0.2 0.3 0.1 1.3 0.3 0.2 0.5 0.4 4.9 0.4 0.4 0.1 0.1 0.2 0.0 1.5 0.6 0.2 2.0 6.8 0.2 0.1 0.6 1.2 1.0 0.9 0.2 1.3 0.9 5.7 0.6 7.9 0.2 0.0 5.2 0.6 0.4 0.9 22.0 17.5 37.8 19.9 2.6 4.8 14.1 43.6 12.0 31.0 41.3 27.9 19.6 45.7 13.9 11.8 22.7 21.4 37.1 14.9 48.1 31.6 16.8 64.5 38.1 12.6 0.1 54.0 36.8 1.0 0.6 53.8 3.7 3.7 16.9 27.1 44.2 30.8 30.3 14.1 56.9 13.1 36.0 14.9 12.2 36.0 57.0 13.8 6.4 35.3 14.0 16.2 37.7 11.6 7.4 25.6 10.0 21.1 12.5 44.6 33.8 27.6 49.3 11.1 29.1 47.1 14.1 37.4 37.0 1.1 0.3 0.3 0.3 0.2 0.1 0.1 0.2 0.2 0.2 0.3 0.1 0.2 1.0 0.5 0.2 0.2 0.3 0.3 0.7 0.6 0.6 1.4 1.3 0.3 0.4 0.4 0.6 0.2 0.6 0.9 2.6 0.0 0.5 0.3 6.5 5.6 5.7 4.4 1.2 9.4 2.9 3.8 1.4 2.8 2.7 0.0 12.5 19.7 4.6 12.8 0.0 1.6 7.9 1.0 3.6 3.6 1.2 55.6 1.6 0.6 41.1 5.2 4.6 3.3 1.3 12.0 2.2 0.4 16.9 1.7 1.5 9.4 2.0 3.0 8.2 6.1 2.5 5.8 3.6 0.0 9.1 9.4 4.1 0.0 0.6 1.4 9.5 0.4 32.5 1.8 0.4 0.2 0.0 101.0 6.6 5.3 8.7 281.1 263.3 5.8 2.0 10.4 7.2 1.2 12.0 3.9 CLU "APOJ, CLI, CLU1, CLU2, KUB1, SGP-2, SP-40, TRPM-2" ENSG00000120885 Clusterin P10909 8 27596917-27614700 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Complement pathway, Immunity, Innate immunity" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 10230.8;liver: 9779.1" "Group enriched" "Detected in all" 4 "Cholangiocytes: 2586.5;Collecting duct cells: 3525.7;Hepatocytes: 4230.2;Muller glia cells: 8522.6" "Cancer enhanced" "Detected in all" "glioma: 1485.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 10 "basophil: 767.1" "Lineage enriched" "Detected in all" 33 "granulocytes: 767.1" "Cell line enhanced" "Detected in all" "HeLa: 3644.3;SK-BR-3: 3500.4;T-47d: 2562.4;U-2 OS: 2225.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000572, CAB016253, HPA075983" Enhanced Supported Cytosol "Secreted to blood" NA NA 169000000000 29000000000 "Cluster 38: Basophils - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 5: Muller glia cells - Visual perception" Cytosol "CAB016253: AB_673562, HPA000572: AB_1078539, HPA075983: " "unprognostic (1.10e-2)" "unprognostic (1.81e-2)" "unprognostic (1.14e-3)" "unprognostic (2.74e-2)" "unprognostic (5.59e-2)" "unprognostic (4.13e-2)" "unprognostic (1.76e-2)" "unprognostic (2.37e-1)" "unprognostic (1.46e-1)" "unprognostic (1.05e-1)" "unprognostic (2.87e-2)" "unprognostic (1.41e-1)" "unprognostic (1.80e-2)" "unprognostic (2.33e-2)" "unprognostic (1.72e-1)" "prognostic favorable (7.66e-5)" "unprognostic (5.29e-2)" 1438.7 3809.7 6730.2 897.0 6536.5 53.2 1423.8 6992.3 8050.5 1389.4 6057.7 1407.9 323.9 1152.5 9148.8 768.6 3543.7 2863.5 617.7 6660.5 8149.9 1170.5 9779.1 827.8 2309.4 10230.8 8450.9 756.7 2246.3 1689.2 827.2 131.2 8001.8 986.4 276.1 3274.6 1453.0 5466.4 114.1 281.9 662.7 1439.9 8813.6 295.4 1081.6 2709.4 7385.0 388.1 2406.8 267.7 2343.1 1777.4 741.0 9752.3 13.0 1673.1 73.2 86.4 401.4 546.1 230.7 297.8 584.8 77.3 40.1 323.4 265.5 6.6 1159.9 267.1 926.6 561.2 318.4 48.1 50.3 1268.7 306.4 741.8 3644.3 403.7 348.8 19.2 1891.2 923.4 189.1 334.0 95.5 719.5 1028.1 10.6 10.1 842.2 27.5 288.4 5.7 56.5 603.3 505.3 197.6 6.5 276.1 236.3 763.0 1220.2 66.7 41.7 412.3 3500.4 18.1 349.1 2562.4 10.3 153.2 24.0 2225.3 131.8 101.9 108.1 419.0 16.1 1808.8 122.4 10.3 767.1 18.4 8.9 19.8 6.2 7.4 0.7 23.1 21.3 6.2 1.6 2.8 7.0 79.8 9.3 1.1 11.8 6.5 1073.6 6730.2 6536.5 6992.3 8050.5 6660.5 8149.9 10230.8 8450.9 8001.8 8813.6 7385.0 9752.3 255.3 32.1 91.8 720.5 16.1 81.3 944.6 134.1 118.9 74.3 475.3 480.4 86.1 2586.5 514.0 3525.7 77.2 116.3 15.2 23.6 41.1 488.3 311.3 196.9 31.1 442.0 9.5 92.4 73.4 620.7 22.7 614.8 226.8 185.6 803.0 31.4 1037.7 4230.2 12.6 30.3 81.0 30.9 28.5 180.5 88.9 789.3 114.3 244.6 206.3 69.3 25.1 8522.6 11.3 61.3 54.3 174.8 15.0 57.2 11.6 200.5 9.9 459.2 709.1 221.4 13.1 334.4 157.7 189.8 20.3 58.8 55.3 85.6 58.7 288.9 49.3 353.7 CLUAP1 "CFAP22, FAP22, FLJ13297, IFT38, KIAA0643" ENSG00000103351 "Clusterin associated protein 1" Q96AJ1 16 3500976-3539048 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 215.5;Endometrial ciliated cells: 119.2;Respiratory ciliated cells: 181.3;Rod photoreceptor cells: 116.8;Spermatocytes: 150.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036976, HPA044191" Uncertain Supported Nucleoplasm,Vesicles NA NA "Cluster 32: T-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm Vesicles "HPA036976: AB_10602209, HPA044191: AB_2678852" "unprognostic (1.78e-1)" "unprognostic (9.28e-3)" "unprognostic (1.21e-1)" "prognostic favorable (3.01e-4)" "unprognostic (1.57e-1)" "unprognostic (3.67e-1)" "unprognostic (4.53e-2)" "unprognostic (3.63e-2)" "unprognostic (2.04e-1)" "unprognostic (8.44e-2)" "unprognostic (3.13e-1)" "unprognostic (6.94e-3)" "unprognostic (5.11e-3)" "unprognostic (8.43e-2)" "unprognostic (2.07e-1)" "unprognostic (8.94e-3)" "unprognostic (1.12e-2)" 9.7 10.7 11.1 5.9 12.6 3.9 14.7 14.2 14.5 21.1 17.8 11.0 4.2 24.2 16.0 11.1 31.8 10.6 11.4 11.2 11.6 18.6 7.7 12.1 7.4 10.4 12.7 24.6 12.2 31.4 11.7 10.6 9.1 17.0 9.8 28.9 9.1 19.9 9.9 5.6 5.4 20.2 9.8 6.6 9.0 40.0 12.0 12.4 22.0 11.6 6.0 10.8 7.8 10.4 15.7 18.3 20.8 28.9 31.4 32.0 11.0 19.9 26.7 31.4 23.7 5.1 31.3 8.2 16.5 33.7 18.8 16.8 14.7 23.6 26.2 6.6 13.1 6.9 10.3 10.5 36.7 12.5 7.2 21.1 25.4 29.1 29.4 33.1 17.2 16.4 21.7 1.0 23.6 19.3 12.0 14.0 21.5 6.6 11.1 25.9 14.3 15.7 45.7 4.9 23.2 19.8 11.6 8.8 14.3 16.0 18.7 28.8 11.5 20.8 13.8 17.1 15.0 12.8 10.9 2.2 8.0 7.3 15.3 6.2 3.6 1.2 6.2 4.2 12.1 7.3 17.8 10.8 6.8 6.1 26.9 18.4 1.3 9.0 2.4 6.6 10.3 5.8 11.1 12.6 14.2 14.5 11.2 11.6 10.4 12.7 9.1 9.8 12.0 10.4 14.5 22.4 20.5 17.0 3.5 5.6 12.3 29.1 14.8 41.0 13.4 13.8 11.7 11.5 30.6 14.7 108.4 20.7 7.5 3.3 43.0 24.3 215.5 119.2 49.7 12.4 17.5 4.6 23.6 8.0 7.7 21.9 6.6 26.4 5.1 28.1 13.6 9.2 10.4 38.7 26.3 7.9 18.3 4.9 5.7 63.4 31.4 5.0 3.6 5.6 18.1 40.7 12.3 11.1 10.3 8.6 5.3 33.1 3.5 9.4 5.3 34.6 181.3 116.8 6.6 24.7 22.7 150.0 58.4 6.4 4.1 9.3 12.1 36.7 9.0 6.5 CLUH "CLU1, KIAA0664" ENSG00000132361 "Clustered mitochondria homolog" O75153 17 2689386-2712663 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 122.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "CACO-2: 266.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031505, HPA044346" Uncertain Supported "Nuclear bodies,Vesicles" NA NA 5500 "Cluster 7: Monocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "Nuclear bodies" "HPA031505: AB_2673912, HPA044346: AB_10962153" "unprognostic (3.48e-2)" "unprognostic (3.97e-2)" "unprognostic (9.02e-2)" "unprognostic (1.43e-1)" "unprognostic (1.49e-1)" "unprognostic (1.15e-2)" "unprognostic (2.85e-2)" "unprognostic (2.84e-2)" "unprognostic (1.84e-1)" "unprognostic (2.69e-2)" "unprognostic (5.64e-2)" "unprognostic (5.11e-2)" "prognostic favorable (1.92e-5)" "unprognostic (4.99e-2)" "unprognostic (1.25e-1)" "unprognostic (1.92e-2)" "unprognostic (6.26e-2)" 30.8 56.7 13.8 18.1 12.7 14.3 28.5 16.3 18.3 19.8 19.7 45.9 46.6 21.3 1.9 67.7 19.2 15.4 80.8 14.5 11.2 50.6 135.0 19.6 14.6 14.6 13.2 17.0 50.4 15.6 20.3 9.0 15.3 24.7 13.2 7.2 32.1 11.8 127.8 47.5 34.2 8.5 9.3 25.2 35.1 25.2 17.3 6.4 25.2 52.9 11.1 29.6 29.2 11.2 69.5 131.9 8.9 33.3 20.2 14.1 99.9 34.9 13.0 41.9 31.0 266.2 30.0 122.6 41.5 19.4 26.9 127.6 45.3 52.9 14.7 43.6 86.4 68.0 112.2 93.9 17.1 53.7 44.1 22.6 29.7 48.9 24.7 9.4 20.5 43.3 81.8 42.2 11.7 79.8 69.6 58.0 28.2 35.8 67.8 104.7 37.0 70.8 26.0 117.3 43.9 32.6 40.0 129.4 44.4 6.6 72.7 31.3 33.7 33.7 44.9 92.2 80.5 18.2 22.9 49.7 35.4 73.2 41.6 0.0 2.2 0.0 1.7 3.1 1.3 2.2 1.0 0.9 2.4 2.2 2.3 2.1 0.2 0.6 2.0 2.7 1.5 0.9 13.8 12.7 16.3 18.3 14.5 11.2 14.6 13.2 15.3 9.3 17.3 11.2 5.8 6.4 20.9 20.9 6.5 30.5 12.0 11.7 16.5 18.5 23.5 22.7 42.1 41.5 16.7 18.4 22.9 9.7 7.6 47.8 11.7 18.4 1.8 12.7 10.8 8.5 25.8 22.1 9.9 18.3 8.2 6.8 22.4 24.6 1.3 18.1 6.8 122.1 13.1 8.4 11.4 38.8 14.2 10.3 6.3 4.0 5.0 7.9 21.4 4.7 7.4 6.5 2.1 7.5 6.2 19.6 21.2 6.0 11.7 22.9 39.2 35.1 14.1 17.1 6.6 12.3 11.3 8.6 17.5 42.4 35.5 8.2 7.2 43.3 68.3 22.5 CLYBL CLB ENSG00000125246 "Citramalyl-CoA lyase" Q8N0X4 13 99606669-99897134 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Lyase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 109.7" "Cell type enhanced" "Detected in many" "Astrocytes: 84.9;Distal tubular cells: 138.9;Hepatocytes: 84.1;Proximal tubular cells: 144.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "OE19: 56.1;SCLC-21H: 53.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039959, HPA040691" Enhanced NA NA 7300 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 8: Non-specific - Mitochondria" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA039959: AB_10793857, HPA040691: AB_10794746" "unprognostic (1.25e-2)" "unprognostic (1.94e-1)" "unprognostic (2.30e-3)" "unprognostic (7.57e-3)" "unprognostic (3.69e-1)" "unprognostic (2.90e-2)" "unprognostic (1.57e-3)" "unprognostic (2.91e-1)" "unprognostic (2.10e-1)" "unprognostic (2.34e-1)" "unprognostic (2.49e-2)" "unprognostic (2.85e-1)" "prognostic favorable (6.66e-16)" "unprognostic (3.74e-2)" "unprognostic (5.41e-2)" "unprognostic (4.78e-2)" "unprognostic (7.82e-2)" 7.1 16.2 11.4 5.5 11.8 5.1 10.5 24.4 12.7 7.7 35.3 20.6 25.0 6.5 13.0 11.3 7.9 6.9 22.6 12.6 8.6 66.0 109.7 5.6 10.4 9.1 9.0 5.7 9.8 14.4 6.7 3.7 7.3 6.9 21.9 7.3 12.3 8.9 43.3 9.3 23.5 6.4 5.6 8.6 8.7 9.3 10.7 5.8 12.3 69.5 10.8 7.4 6.9 8.8 0.4 2.3 16.6 7.5 7.6 7.0 3.6 0.8 1.6 1.4 2.6 0.3 12.4 3.0 4.8 1.0 3.2 3.9 1.5 2.8 1.8 15.3 2.4 19.2 4.9 11.8 5.2 10.4 1.3 3.8 8.3 0.2 6.4 1.6 2.2 15.7 2.7 9.8 1.6 4.3 4.7 14.3 10.8 56.1 3.4 6.0 0.7 7.1 16.6 1.1 53.1 8.1 3.4 3.8 3.6 5.9 8.0 13.2 0.3 0.7 1.9 1.4 2.7 22.3 4.7 0.6 11.3 14.9 2.3 1.7 4.5 0.5 9.9 10.0 12.0 14.5 17.4 13.9 9.4 15.7 13.3 15.8 0.6 14.2 4.8 10.3 24.2 7.7 11.4 11.8 24.4 12.7 12.6 8.6 9.1 9.0 7.3 5.6 10.7 8.8 7.4 6.4 5.0 84.9 8.6 5.5 9.1 18.4 8.6 2.3 8.9 11.3 36.1 21.5 10.9 14.7 2.1 14.3 9.2 17.9 138.9 11.6 1.6 6.1 4.1 6.2 1.2 2.5 30.6 8.1 3.2 5.9 5.6 4.4 6.3 7.1 4.6 84.1 7.6 0.0 25.6 11.5 10.2 6.7 4.5 4.8 2.1 5.4 16.0 48.7 4.4 6.5 7.2 21.6 9.5 4.0 13.8 4.1 3.8 4.3 23.1 144.7 4.1 5.0 0.0 7.6 18.1 3.0 10.5 6.9 6.3 7.4 8.3 13.6 19.1 6.7 CMAS ENSG00000111726 "Cytidine monophosphate N-acetylneuraminic acid synthetase" Q8NFW8 12 22046218-22065674 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 532.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039905 Supported Uncertain Nucleoli,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 45: Intestine - Brush border" "Cluster 36: HEL - Hemostasis" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol Nucleoli "HPA039905: AB_10795237" "unprognostic (5.54e-2)" "unprognostic (4.10e-2)" "unprognostic (4.25e-1)" "unprognostic (5.39e-3)" "unprognostic (1.94e-2)" "unprognostic (3.99e-2)" "unprognostic (2.30e-2)" "unprognostic (4.17e-3)" "unprognostic (1.53e-2)" "unprognostic (1.01e-1)" "unprognostic (4.44e-1)" "unprognostic (7.53e-2)" "prognostic unfavorable (7.19e-4)" "unprognostic (2.27e-1)" "unprognostic (1.91e-2)" "unprognostic (3.65e-1)" "unprognostic (2.03e-1)" 19.7 57.0 46.6 23.2 51.1 47.9 32.9 40.3 57.8 29.2 35.8 77.8 66.2 23.5 69.0 71.6 21.8 24.4 42.6 51.2 57.3 28.9 72.2 18.1 24.2 43.8 57.1 25.3 42.5 79.4 30.0 34.0 57.1 36.7 71.9 24.8 32.6 26.7 44.0 29.3 63.6 27.7 41.8 20.1 29.7 69.9 49.0 19.8 23.8 41.1 26.1 24.2 40.3 44.0 63.4 50.2 59.5 29.3 47.0 57.5 88.8 43.2 46.2 45.0 47.2 114.1 72.0 56.5 41.3 37.3 83.9 50.9 35.8 60.1 60.7 75.0 45.4 169.1 38.8 57.2 43.2 45.4 85.5 38.5 56.4 58.1 86.3 61.5 61.3 58.7 108.8 28.1 80.9 83.8 52.0 105.3 147.5 69.4 69.5 36.2 63.6 53.7 56.0 67.8 23.8 42.0 34.2 59.6 51.9 120.2 82.3 62.0 45.5 51.2 42.4 46.2 81.1 19.4 26.0 74.9 83.6 34.6 54.3 22.7 27.3 32.1 20.4 29.7 26.1 19.0 26.9 27.0 31.5 18.2 24.2 24.6 2.8 36.9 27.4 20.2 33.8 25.5 46.6 51.1 40.3 57.8 51.2 57.3 43.8 57.1 57.1 41.8 49.0 44.0 21.5 12.8 17.5 12.4 19.2 29.2 76.8 117.2 14.8 38.3 31.9 21.2 72.7 41.5 102.3 23.9 4.2 175.2 17.8 158.1 76.3 56.6 12.4 17.2 19.6 36.8 41.6 153.9 38.7 83.6 141.3 41.7 21.9 20.0 22.8 28.2 34.2 63.6 66.2 35.3 29.2 118.2 93.6 29.8 22.0 19.0 25.4 32.5 44.4 8.4 45.3 33.4 26.8 16.6 25.5 79.7 156.2 27.8 16.7 112.3 133.6 87.0 82.5 20.4 19.7 30.4 42.3 112.2 97.1 52.3 44.5 532.6 24.6 63.0 90.8 190.6 CMC1 "C3orf68, MGC61571" ENSG00000187118 "C-X9-C motif containing 1" Q7Z7K0 3 28241584-28325142 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "dendritic cells: 418.8;NK-cells: 694.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "NK-cell: 162.2" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043333 Approved NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 63: NK-cells & T-cells - Immune response" "HPA043333: AB_10797139" "unprognostic (1.16e-1)" "unprognostic (8.01e-3)" "unprognostic (6.90e-3)" "unprognostic (8.88e-2)" "unprognostic (1.83e-1)" "unprognostic (1.02e-1)" "unprognostic (3.81e-2)" "unprognostic (3.64e-1)" "unprognostic (1.26e-1)" "unprognostic (3.80e-3)" "unprognostic (3.09e-1)" "unprognostic (2.30e-2)" "prognostic favorable (6.81e-4)" "unprognostic (3.54e-1)" "unprognostic (8.12e-2)" "unprognostic (4.55e-1)" "prognostic favorable (5.52e-4)" 15.9 18.7 9.4 4.8 9.4 4.9 11.8 9.6 14.3 10.6 9.7 14.7 7.6 10.1 5.3 11.9 11.4 4.0 34.6 9.1 9.8 24.2 24.8 11.5 4.3 9.4 9.4 10.5 11.8 5.0 16.9 6.5 9.6 11.4 4.0 3.2 9.3 4.5 24.8 9.1 9.9 3.4 9.3 12.3 14.7 4.2 9.6 4.1 9.6 13.7 2.9 12.2 11.4 9.5 15.2 24.7 6.8 7.1 18.5 18.5 17.4 20.0 6.1 8.5 8.5 7.3 21.0 13.5 24.8 3.3 14.2 7.1 8.7 18.7 5.1 30.4 21.9 14.5 22.1 16.2 19.1 9.3 10.9 9.9 13.8 8.6 10.8 19.2 10.7 34.0 14.2 19.3 6.9 13.7 13.6 25.1 7.9 15.2 27.0 12.7 7.9 11.0 10.9 6.7 6.7 12.5 14.7 9.1 44.9 9.4 18.8 27.4 12.9 9.1 11.2 13.8 13.1 8.9 22.0 19.7 24.1 20.5 19.2 24.2 21.9 17.1 40.2 28.9 57.7 18.4 25.4 69.6 29.9 17.1 18.8 41.9 6.7 162.2 32.9 30.4 27.2 29.4 9.4 9.4 9.6 14.3 9.1 9.8 9.4 9.4 9.6 9.3 9.6 9.5 51.5 38.5 33.0 26.4 28.3 21.2 38.0 68.6 23.9 16.2 40.0 53.5 202.8 30.0 42.3 31.3 10.4 68.4 418.8 68.2 221.1 61.3 226.4 67.2 38.5 42.1 28.2 128.6 51.5 58.6 42.4 39.4 24.5 42.5 36.7 25.9 50.3 88.7 64.5 3.3 61.2 71.7 67.1 61.7 26.2 31.1 49.4 36.4 30.2 41.2 53.8 37.4 694.1 53.8 63.3 66.1 71.3 39.1 32.7 42.9 56.2 134.4 56.0 25.4 39.5 31.2 71.6 26.3 49.3 28.6 32.8 31.5 222.5 58.2 67.9 42.2 CMC2 "C16orf61, DC13, MGC45036" ENSG00000103121 "C-X9-C motif containing 2" Q9NRP2 16 80966448-81020270 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 263.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA006871, CAB026396" Approved Supported Mitochondria NA Yes "Cluster 15: NK-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB026396: , HPA006871: AB_1845581" "unprognostic (2.43e-1)" "unprognostic (3.63e-2)" "unprognostic (1.70e-1)" "unprognostic (3.52e-2)" "unprognostic (1.50e-1)" "unprognostic (3.01e-3)" "unprognostic (2.48e-2)" "unprognostic (6.36e-2)" "unprognostic (9.20e-2)" "unprognostic (3.84e-3)" "unprognostic (3.48e-2)" "unprognostic (4.57e-3)" "prognostic favorable (2.64e-5)" "unprognostic (1.08e-1)" "unprognostic (1.51e-1)" "unprognostic (1.17e-1)" "unprognostic (2.68e-1)" 22.1 24.6 47.6 14.0 50.0 45.2 17.0 49.0 60.2 17.2 41.2 22.7 19.1 12.4 16.6 20.4 11.6 17.0 68.4 48.4 50.7 43.5 44.0 24.3 22.4 47.6 47.6 13.7 27.3 30.4 26.1 16.3 47.5 34.9 16.9 16.1 14.8 12.4 54.0 15.3 20.3 15.0 48.3 21.7 27.2 47.0 51.2 30.1 16.2 33.9 17.1 20.7 17.0 54.2 74.8 103.1 76.1 43.7 25.1 25.0 44.9 73.4 33.1 64.0 32.9 71.7 49.9 33.5 53.3 35.8 62.9 52.6 52.5 42.8 84.9 50.9 63.3 51.9 68.4 78.6 40.6 43.5 85.4 21.8 23.8 77.7 43.5 29.2 57.1 83.1 124.2 43.5 63.3 140.1 68.1 138.4 45.2 59.7 62.0 84.2 41.2 43.8 50.4 35.9 64.1 37.1 110.6 39.8 87.3 39.4 78.7 39.2 32.8 57.9 82.0 56.6 75.3 45.4 107.6 193.8 44.6 55.3 69.1 33.2 28.0 37.3 28.8 29.6 27.5 39.1 36.5 30.1 31.6 34.9 25.3 29.2 12.0 44.6 34.2 45.3 64.4 18.0 47.6 50.0 49.0 60.2 48.4 50.7 47.6 47.6 47.5 48.3 51.2 54.2 41.2 35.3 38.8 48.0 54.9 97.6 75.5 53.9 48.9 31.9 48.0 50.7 204.7 42.9 36.5 47.8 54.2 44.8 78.9 29.5 158.5 34.4 95.4 44.2 33.7 36.0 38.3 55.5 88.6 38.0 62.8 45.0 42.8 45.2 95.5 37.3 25.4 86.0 51.4 30.3 62.2 42.9 59.0 70.5 84.1 168.3 24.5 59.7 65.8 14.0 33.8 29.3 51.5 48.7 74.0 39.0 31.9 29.3 83.5 69.1 48.5 166.1 31.4 16.7 59.2 33.3 47.0 263.5 121.5 65.0 102.1 38.0 84.7 55.3 44.8 74.4 CMPK2 "NDK, TYKi, UMP-CMPK2" ENSG00000134326 "Cytidine/uridine monophosphate kinase 2" Q5EBM0 2 6840570-6866635 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Pyrimidine biosynthesis" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.6;salivary gland: 8.5" "Cell type enriched" "Detected in many" 4 "Erythroid cells: 86.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 4.9" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BJ hTERT+ SV40 Large T+: 12.8;BJ hTERT+ SV40 Large T+ RasG12V: 11.9;HEL: 20.3;MOLT-4: 11.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041430 Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 36: HEL - Hemostasis" "Cluster 6: Erythroid cells - Oxygen transport" Mitochondria Nucleoplasm "HPA041430: AB_10796674" "unprognostic (2.37e-1)" "unprognostic (6.07e-2)" "unprognostic (5.71e-2)" "prognostic unfavorable (4.71e-4)" "unprognostic (1.82e-1)" "unprognostic (5.08e-2)" "unprognostic (3.80e-2)" "unprognostic (8.93e-2)" "unprognostic (6.63e-2)" "unprognostic (4.54e-3)" "unprognostic (7.39e-3)" "unprognostic (1.43e-1)" "unprognostic (1.09e-3)" "unprognostic (1.28e-1)" "unprognostic (1.77e-2)" "unprognostic (7.69e-2)" "unprognostic (4.32e-2)" 2.1 1.4 1.7 1.4 2.8 6.4 1.8 0.7 1.8 1.4 1.7 1.3 1.6 0.9 0.3 0.7 0.7 0.8 2.1 1.2 1.9 1.1 0.9 2.8 1.3 6.0 3.0 0.4 1.3 0.9 1.1 1.6 3.2 0.7 0.6 0.1 8.5 0.7 1.1 0.4 2.2 0.9 10.6 3.5 2.9 2.0 2.0 1.9 1.2 1.6 0.7 0.9 0.6 1.5 0.3 0.0 0.1 0.0 0.0 0.0 2.5 0.0 0.2 12.8 11.9 0.0 1.4 3.1 0.8 0.0 3.3 0.2 0.0 0.0 0.0 0.3 0.2 20.3 0.0 0.0 0.0 0.6 1.8 0.1 0.0 0.2 0.0 0.0 0.0 2.0 5.8 0.1 0.0 0.1 11.8 3.6 0.3 0.0 1.0 3.6 0.0 0.0 0.0 0.4 0.4 0.5 0.2 0.0 1.9 0.0 0.0 1.3 0.0 0.0 0.2 0.0 0.0 3.3 0.4 0.0 0.0 3.6 0.8 3.1 1.6 4.9 0.3 3.9 0.2 1.1 0.2 0.2 1.1 0.1 0.2 0.3 1.1 0.5 2.0 0.1 0.4 0.7 1.7 2.8 0.7 1.8 1.2 1.9 6.0 3.0 3.2 10.6 2.0 1.5 20.8 3.2 7.5 0.0 1.9 0.4 0.9 0.5 0.0 1.5 1.7 1.3 1.6 0.0 0.5 1.8 0.0 3.0 3.4 10.0 1.9 2.6 4.0 5.4 0.8 11.7 7.2 86.3 1.9 6.6 2.9 2.7 11.2 1.0 2.5 1.7 7.1 1.4 19.5 0.0 2.5 2.5 0.0 12.3 2.8 1.6 1.5 11.3 0.0 9.4 11.9 5.3 3.1 1.5 0.2 6.2 8.4 5.7 2.1 1.0 8.4 0.7 4.1 0.2 0.0 2.2 2.0 2.7 4.4 0.7 0.4 0.8 4.5 1.6 1.6 2.0 CMSS1 "C3orf26, MGC4308" ENSG00000184220 "Cms1 ribosomal small subunit homolog" Q9BQ75 3 99817837-100181732 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 215.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042820 Uncertain Approved "Nucleoplasm,Nuclear membrane,Nucleoli,Mitochondria" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoli "Nucleoplasm, Nuclear membrane, Mitochondria" "HPA042820: AB_10795763" "unprognostic (1.50e-1)" "unprognostic (8.28e-2)" "unprognostic (4.61e-2)" "prognostic unfavorable (3.15e-6)" "unprognostic (2.13e-2)" "unprognostic (2.39e-3)" "prognostic unfavorable (5.92e-10)" "unprognostic (1.50e-1)" "unprognostic (5.92e-2)" "unprognostic (5.83e-2)" "unprognostic (6.71e-2)" "prognostic unfavorable (3.10e-4)" "unprognostic (2.18e-3)" "unprognostic (1.56e-1)" "unprognostic (2.26e-1)" "unprognostic (3.25e-1)" "unprognostic (4.04e-2)" 24.5 33.1 23.0 15.8 21.7 20.8 23.4 26.7 30.1 22.4 17.8 21.0 8.6 21.8 9.7 15.8 20.9 10.5 28.2 21.8 20.9 20.7 15.0 15.8 17.1 22.8 20.1 23.6 26.7 21.8 24.5 11.6 19.6 16.0 11.6 24.6 14.0 13.3 69.4 17.4 12.6 13.2 17.9 13.8 16.4 30.3 21.3 16.7 14.8 29.9 15.0 24.5 18.1 21.7 116.2 51.0 50.0 72.6 34.7 40.1 51.0 53.5 28.8 93.3 77.0 64.1 37.5 126.3 90.6 28.2 82.4 68.4 70.3 60.2 120.3 66.8 66.5 99.9 32.9 53.2 62.6 137.0 51.3 28.2 56.7 71.4 116.6 30.3 65.2 100.9 63.5 78.1 67.0 78.8 110.3 126.4 73.0 109.4 126.1 49.1 81.3 134.1 57.2 27.5 139.9 58.9 52.8 42.5 125.0 47.8 51.4 84.0 18.5 73.6 207.4 43.3 109.8 56.3 121.1 244.9 49.1 149.4 124.8 1.0 11.0 2.3 22.2 27.3 32.0 57.3 32.8 30.3 23.8 55.7 41.3 42.0 4.1 28.6 25.1 62.1 33.9 18.2 23.0 21.7 26.7 30.1 21.8 20.9 22.8 20.1 19.6 17.9 21.3 21.7 26.7 6.4 19.4 48.6 41.3 62.2 37.4 45.5 26.2 32.8 43.8 40.4 41.7 42.9 23.2 62.5 18.8 41.7 25.1 8.5 97.8 42.1 165.0 21.7 56.8 38.7 15.0 30.9 154.3 47.7 56.6 44.3 9.7 19.8 62.1 47.7 24.7 61.4 27.2 127.9 132.8 14.4 16.2 7.9 45.5 215.8 50.7 18.7 37.4 58.1 12.8 28.0 19.6 114.1 116.2 35.8 4.6 58.6 36.2 82.8 1.1 87.9 22.4 27.0 26.3 67.3 50.1 163.4 146.1 21.3 66.1 21.9 30.1 54.1 22.6 27.0 CMTM6 "CKLFSF6, FLJ20396" ENSG00000091317 "CKLF like MARVEL transmembrane domain containing 6" Q9NX76 3 32481312-32502852 "Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 815.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026980, HPA063491" Enhanced Approved Vesicles NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 41: Macrophages - Immune response" Vesicles "HPA026980: AB_10602801, HPA063491: " "unprognostic (1.32e-2)" "unprognostic (3.04e-1)" "unprognostic (3.34e-2)" "unprognostic (1.81e-2)" "unprognostic (7.25e-2)" "unprognostic (8.20e-2)" "unprognostic (2.95e-2)" "unprognostic (1.99e-1)" "unprognostic (2.44e-3)" "unprognostic (2.95e-1)" "unprognostic (1.04e-3)" "unprognostic (6.79e-2)" "unprognostic (2.27e-1)" "unprognostic (7.23e-2)" "unprognostic (6.58e-2)" "unprognostic (3.74e-2)" "unprognostic (1.55e-3)" 40.3 26.2 11.6 69.0 11.4 97.3 54.4 11.7 13.5 50.4 24.8 47.7 26.7 46.3 41.0 40.3 176.6 50.3 18.5 10.8 13.4 40.0 132.4 54.3 53.9 14.5 12.5 18.6 23.5 41.6 9.2 70.1 14.3 48.6 58.4 13.0 33.2 39.9 5.0 49.4 29.5 41.6 14.5 55.4 46.9 40.4 13.5 47.8 61.7 13.6 78.3 79.0 18.9 14.7 107.4 34.2 66.5 50.1 112.1 111.0 292.4 77.5 110.4 79.7 91.5 36.6 174.4 63.5 86.1 104.6 53.8 67.6 47.0 128.9 108.2 285.4 57.3 80.4 22.8 54.5 79.6 135.3 153.0 110.5 81.3 92.0 68.6 128.2 130.3 60.9 39.8 116.0 103.0 33.4 81.9 70.0 59.3 88.6 50.0 68.6 51.7 49.9 111.1 147.9 15.3 44.3 70.5 39.5 76.1 66.9 58.3 133.5 117.8 88.0 57.9 86.7 94.1 59.6 63.9 58.6 61.4 116.8 112.1 176.8 84.4 208.0 29.1 133.4 32.8 54.4 38.1 28.3 72.7 42.2 22.0 24.7 313.4 65.1 210.2 38.6 46.3 108.6 11.6 11.4 11.7 13.5 10.8 13.4 14.5 12.5 14.3 14.5 13.5 14.7 57.0 35.3 49.9 12.4 243.7 96.0 82.4 159.3 55.2 13.9 233.0 57.5 5.8 60.1 112.0 95.6 12.5 253.6 122.5 88.0 33.2 113.8 12.3 129.1 68.3 70.7 132.1 41.2 14.2 83.0 101.7 74.9 63.2 180.9 126.8 186.5 124.9 305.2 156.5 50.5 19.2 117.6 118.0 310.1 815.8 8.4 39.4 326.0 81.8 30.0 425.8 130.1 71.1 18.1 9.4 136.7 46.1 42.9 104.7 147.1 23.8 63.4 183.0 17.3 39.5 32.9 74.3 36.1 20.2 89.7 126.6 261.7 120.9 50.3 64.6 110.3 CMTR2 "AFT, FLJ11171, FTSJD1, MTr2" ENSG00000180917 "Cap methyltransferase 2" Q8IYT2 16 71281389-71289715 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "mRNA capping, mRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 95.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041700, HPA048265" Uncertain Approved "Nuclear speckles,Cell Junctions" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 52: Non-specific - Transcription" "Cell Junctions" "Nuclear speckles" "HPA041700: AB_2677623, HPA048265: AB_2680334" "unprognostic (1.27e-1)" "unprognostic (2.49e-2)" "unprognostic (2.94e-3)" "unprognostic (1.43e-1)" "unprognostic (6.30e-2)" "unprognostic (3.82e-2)" "unprognostic (1.93e-3)" "unprognostic (2.86e-2)" "unprognostic (7.93e-2)" "unprognostic (3.41e-1)" "unprognostic (1.85e-2)" "unprognostic (7.39e-2)" "prognostic favorable (4.97e-5)" "unprognostic (9.55e-2)" "unprognostic (5.99e-2)" "unprognostic (1.54e-1)" "unprognostic (5.34e-2)" 6.7 8.8 4.0 10.3 4.6 7.2 15.9 4.6 4.2 7.6 8.0 10.1 14.9 8.5 12.2 14.3 9.0 9.4 7.0 3.2 4.7 12.5 14.3 11.4 14.4 5.1 4.4 11.2 8.1 10.7 7.8 10.6 4.8 10.8 10.4 7.3 13.3 8.0 5.7 10.3 14.2 9.0 5.2 13.6 10.0 13.8 4.9 10.7 14.1 5.7 17.9 9.7 7.6 6.6 17.8 11.6 23.2 19.5 18.9 15.3 10.6 14.9 18.2 17.4 18.4 10.6 26.5 10.0 18.4 13.7 18.9 19.4 11.1 14.2 24.9 10.5 7.9 22.3 13.1 8.3 20.3 16.8 37.7 12.7 24.7 15.4 17.9 12.8 18.5 22.2 11.6 6.6 31.1 15.9 18.8 23.1 11.0 14.2 6.7 28.5 10.2 24.5 16.3 19.5 12.0 12.8 15.1 12.2 15.4 10.3 18.0 10.4 18.7 21.1 15.1 15.5 11.4 13.3 17.6 21.3 14.7 14.6 16.8 22.6 9.6 9.2 10.8 10.3 13.2 13.1 10.6 11.7 13.7 12.0 11.4 11.1 0.7 16.6 6.9 3.9 9.8 11.4 4.0 4.6 4.6 4.2 3.2 4.7 5.1 4.4 4.8 5.2 4.9 6.6 11.4 3.2 11.8 13.7 28.1 14.1 14.5 10.7 15.9 20.3 23.9 13.7 8.6 20.0 9.4 16.5 31.3 24.2 30.2 25.8 7.9 12.2 95.6 12.6 15.1 14.6 18.6 17.0 9.9 9.7 12.7 11.5 15.8 11.5 8.2 26.1 18.9 32.7 16.1 15.2 10.3 20.5 18.3 18.0 11.4 30.9 16.8 13.6 1.8 21.5 17.8 12.1 51.5 17.6 21.5 12.9 15.2 12.4 17.9 13.5 46.3 17.7 6.5 25.5 6.6 11.1 10.1 26.1 13.8 22.0 24.3 26.4 20.0 21.8 17.9 18.2 CNGA2 "CNCA, CNCA1, CNG2, FLJ46312, OCNC1, OCNCa, OCNCALPHA" ENSG00000183862 "Cyclic nucleotide gated channel subunit alpha 2" Q16280 X 151738451-151745304 "Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Olfaction, Sensory transduction, Transport" "Calmodulin-binding, Ion channel, Ligand-gated ion channel" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA015065 Uncertain NA NA "HPA015065: AB_1847034" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CNKSR3 "FLJ31349, MAGI1" ENSG00000153721 "CNKSR family member 3" Q6P9H4 6 154387515-154510685 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 109.6;Glandular and luminal cells: 155.4;Oligodendrocytes: 142.3;Skeletal myocytes: 211.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 21.1" "CAB037133, HPA049651" Approved Supported Mitochondria,Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 44: Endometrium - Transcription" Cytosol Mitochondria "CAB037133: AB_477217, HPA049651: AB_2680841" "unprognostic (3.07e-1)" "unprognostic (3.25e-2)" "unprognostic (1.57e-1)" "unprognostic (2.34e-1)" "unprognostic (5.62e-2)" "unprognostic (1.25e-2)" "unprognostic (1.37e-1)" "unprognostic (5.78e-2)" "unprognostic (1.98e-1)" "unprognostic (1.40e-1)" "unprognostic (4.67e-3)" "unprognostic (4.90e-2)" "prognostic favorable (6.00e-4)" "unprognostic (4.23e-2)" "unprognostic (8.79e-2)" "unprognostic (1.57e-3)" "unprognostic (3.38e-1)" 3.7 1.1 6.4 1.9 7.6 0.9 3.2 4.8 5.5 4.0 15.0 6.5 5.8 7.6 1.9 13.3 4.1 4.9 6.4 3.6 4.2 7.7 9.7 3.7 1.4 7.8 8.3 6.1 18.9 0.7 2.3 5.6 7.2 3.3 3.4 2.6 5.7 4.8 1.1 3.9 6.4 6.6 5.3 4.5 4.0 4.4 12.7 2.1 2.1 1.4 2.5 4.3 5.3 13.3 0.4 4.9 3.3 6.8 5.8 4.1 0.4 6.0 3.5 10.2 8.3 21.1 0.5 0.1 6.4 6.6 3.4 2.1 9.5 0.7 5.3 0.0 6.3 15.4 1.0 12.1 2.5 0.0 2.7 6.1 3.2 3.9 4.1 1.6 3.2 1.3 2.2 0.1 2.8 1.2 0.1 0.2 2.3 4.1 6.2 4.6 5.9 8.0 11.7 3.1 2.0 12.6 2.8 1.5 1.3 1.4 0.0 1.3 3.7 0.9 3.0 7.7 4.0 0.1 0.0 0.2 0.2 0.3 4.4 0.6 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.7 0.1 0.1 0.2 0.0 0.0 6.4 7.6 4.8 5.5 3.6 4.2 7.8 8.3 7.2 5.3 12.7 13.3 24.7 12.8 38.4 9.4 0.9 26.5 15.4 7.8 12.5 2.0 11.0 8.3 33.8 30.0 20.2 25.8 0.0 9.2 0.4 31.0 9.8 20.3 42.5 109.6 14.7 66.8 43.2 15.6 23.8 12.3 1.1 12.9 9.2 155.4 5.7 10.8 61.8 65.9 1.7 0.0 1.5 18.4 10.2 7.1 22.5 23.6 5.9 3.5 32.0 24.4 0.8 22.8 0.0 54.8 142.3 7.3 18.5 10.5 0.5 18.7 43.6 31.8 11.7 2.5 0.0 211.8 8.0 1.2 6.3 29.4 23.9 21.5 2.6 14.8 14.1 10.0 CNOT1 "AD-005, CDC39, KIAA1007, NOT1, NOT1H" ENSG00000125107 "CCR4-NOT transcription complex subunit 1" A5YKK6 16 58519951-58629885 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "RNA-mediated gene silencing, Transcription, Transcription regulation, Translation regulation" "Developmental protein, Repressor" "Autism spectrum disorder, Disease variant, Holoprosencephaly, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046577, HPA049664" Approved Supported Cytosol NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA046577: AB_2679706, HPA049664: AB_2680844" "unprognostic (1.30e-2)" "unprognostic (6.86e-2)" "unprognostic (9.25e-3)" "unprognostic (1.66e-1)" "unprognostic (2.39e-2)" "unprognostic (7.11e-2)" "unprognostic (3.58e-2)" "unprognostic (2.19e-1)" "unprognostic (6.43e-2)" "unprognostic (6.99e-2)" "unprognostic (1.83e-2)" "unprognostic (6.63e-2)" "unprognostic (1.33e-3)" "unprognostic (2.31e-1)" "unprognostic (1.12e-1)" "unprognostic (5.53e-2)" "unprognostic (1.52e-1)" 29.8 35.2 8.4 46.9 10.7 45.6 36.3 17.4 11.5 34.7 33.5 60.1 55.0 31.8 27.6 73.1 38.9 28.3 26.3 8.6 9.4 39.8 36.0 33.3 58.1 11.5 10.5 39.2 41.1 59.7 21.2 35.1 11.3 31.2 57.3 32.4 38.8 30.6 52.4 43.1 52.3 33.7 8.9 42.9 42.1 108.2 10.6 76.4 42.4 44.1 69.5 49.1 38.6 15.2 128.8 148.2 110.0 88.1 52.1 66.2 127.6 99.6 85.8 111.4 82.0 167.6 75.3 194.0 47.4 75.8 65.5 122.3 177.9 101.0 149.2 72.5 98.8 150.4 121.8 193.7 70.8 235.8 162.4 64.0 67.5 129.7 151.5 66.9 87.7 107.2 181.0 55.3 76.4 52.0 182.6 61.2 114.4 84.9 127.2 229.0 189.5 122.7 62.4 180.0 90.9 58.6 336.0 113.5 56.0 100.5 67.9 121.3 100.9 81.3 80.0 62.2 88.7 124.7 138.2 390.3 85.5 99.4 76.9 18.3 12.1 13.4 13.8 15.6 18.2 14.7 12.9 14.0 14.6 13.8 12.1 12.6 18.6 15.4 22.5 7.3 15.4 11.5 8.4 10.7 17.4 11.5 8.6 9.4 11.5 10.5 11.3 8.9 10.6 15.2 44.4 16.0 42.9 33.0 57.8 47.4 32.6 42.9 25.6 28.2 33.9 27.9 23.8 37.1 45.2 23.9 29.2 33.7 86.3 64.5 9.8 29.8 107.7 57.6 48.0 31.3 36.1 45.0 31.7 47.0 29.9 30.7 35.2 78.2 32.2 45.9 23.9 42.3 35.7 40.4 35.6 54.2 24.4 51.5 39.5 38.6 24.8 46.4 19.6 42.2 50.0 20.0 34.0 42.3 54.9 42.5 34.9 32.4 59.8 43.6 60.1 22.9 51.6 24.3 32.9 38.7 30.4 136.6 64.3 56.0 47.0 37.9 52.1 27.9 64.5 61.2 CNR1 "CANN6, CB-R, CB1, CB1A, CB1K5, CNR" ENSG00000118432 "Cannabinoid receptor 1" P21554 6 88139864-88166359 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 23.0;brain: 25.1" "Cell type enhanced" "Detected in some" "Excitatory neurons: 44.6;Inhibitory neurons: 200.3;Sertoli cells: 98.6" "Cancer enriched" "Detected in many" 13 "glioma: 12.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "ASC diff: 81.4;HSkMC: 53.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042256, HPA069945" Enhanced Supported Supported "Plasma membrane,Actin filaments" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 10: Brain - Neuronal signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Actin filaments" "HPA042256: AB_2677917, HPA069945: " "unprognostic (1.28e-1)" "unprognostic (7.04e-2)" "unprognostic (4.61e-2)" "unprognostic (4.08e-3)" "unprognostic (1.21e-1)" "unprognostic (1.07e-3)" "unprognostic (1.37e-1)" "unprognostic (2.07e-2)" "unprognostic (2.49e-1)" "unprognostic (1.16e-2)" "unprognostic (2.74e-2)" "unprognostic (2.68e-1)" "unprognostic (1.70e-1)" "unprognostic (5.59e-3)" "unprognostic (2.68e-3)" "unprognostic (5.88e-2)" "unprognostic (7.00e-2)" 23.0 5.4 10.4 3.5 25.1 0.7 16.9 7.5 22.8 5.7 0.0 12.3 1.1 6.9 2.6 2.4 11.2 2.0 1.0 19.5 11.8 0.9 0.1 4.0 4.4 9.9 1.1 3.8 1.5 0.5 20.7 3.1 0.5 2.9 2.9 1.5 2.6 2.1 2.4 3.8 10.5 3.6 0.0 1.7 4.3 1.2 18.0 1.3 5.1 1.2 6.6 4.1 5.1 3.0 0.0 0.1 3.8 0.0 81.4 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.2 1.9 2.9 0.0 5.3 0.0 0.0 53.8 0.0 0.0 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.4 0.5 0.0 6.8 0.0 1.7 0.1 0.0 0.0 0.0 0.3 0.0 1.4 4.9 0.0 0.0 0.1 0.0 0.0 1.6 7.1 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 10.4 25.1 7.5 22.8 19.5 11.8 9.9 1.1 0.5 0.0 18.0 3.0 3.4 0.0 10.4 3.6 7.1 0.6 0.5 0.0 0.0 1.7 0.1 0.4 0.9 1.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.2 0.0 0.4 3.8 0.0 0.0 44.6 0.0 0.0 0.9 1.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 200.3 0.0 0.0 0.3 0.8 0.0 1.5 0.2 0.0 5.6 0.0 0.0 0.0 9.0 3.2 0.0 0.1 0.4 4.2 0.0 0.0 0.0 0.0 0.2 98.6 6.4 12.4 0.0 0.5 0.2 0.1 0.1 0.5 0.0 0.0 0.8 CNST "C1orf71, FLJ32001, PPP1R64" ENSG00000162852 "Consortin, connexin sorting protein" Q6PJW8 1 246566444-246668595 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007225, HPA007226" Approved Supported Vesicles NA NA 480000 "Cluster 37: B-cells - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 1: K-562 - Erythropoiesis" "Cluster 44: Endometrium - Transcription" Vesicles "HPA007225: AB_1848869, HPA007226: AB_2667782" "unprognostic (1.55e-2)" "unprognostic (9.75e-2)" "unprognostic (3.33e-2)" "unprognostic (9.76e-2)" "unprognostic (2.78e-1)" "unprognostic (4.28e-2)" "unprognostic (3.72e-2)" "unprognostic (7.28e-3)" "unprognostic (1.01e-1)" "unprognostic (1.93e-1)" "unprognostic (3.52e-2)" "unprognostic (3.47e-2)" "unprognostic (2.73e-3)" "unprognostic (6.17e-2)" "unprognostic (2.63e-1)" "unprognostic (8.77e-3)" "unprognostic (2.26e-1)" 13.1 19.2 8.8 10.5 9.7 23.5 10.9 14.4 16.1 9.0 17.1 13.7 10.2 9.0 8.1 16.7 8.8 8.7 8.9 10.3 11.1 8.6 23.5 9.9 16.7 6.9 7.8 10.5 10.2 11.3 7.5 9.3 8.4 8.1 12.0 16.8 7.2 7.3 31.8 10.1 13.2 10.1 5.6 10.4 8.4 12.9 7.6 14.3 13.9 39.0 13.4 11.3 8.8 9.5 8.4 11.0 7.9 7.0 12.8 14.7 16.0 26.9 26.5 26.7 20.2 10.5 10.9 24.6 11.7 26.9 7.9 8.6 12.3 9.2 36.2 13.8 4.2 28.9 10.4 8.0 18.4 14.5 53.5 14.0 8.7 25.9 27.4 13.2 8.4 13.0 37.3 10.5 15.3 6.1 15.9 6.7 25.9 11.7 9.5 15.5 14.2 20.1 10.1 24.4 18.0 21.6 11.5 6.7 34.0 9.2 12.3 12.6 12.0 33.0 7.9 13.8 18.5 31.8 43.8 25.0 8.1 21.2 32.5 47.1 8.1 23.9 14.4 8.8 16.1 35.6 24.8 13.6 8.1 35.7 31.1 16.9 10.7 15.1 22.2 11.7 33.2 15.9 8.8 9.7 14.4 16.1 10.3 11.1 6.9 7.8 8.4 5.6 7.6 9.5 41.3 12.8 17.2 21.2 46.0 24.9 21.5 6.7 27.3 31.5 10.2 7.5 14.3 12.8 17.7 3.7 14.6 4.0 18.2 46.9 7.9 6.9 44.7 43.7 17.2 29.0 15.0 25.2 58.5 6.0 6.2 22.5 16.3 68.3 40.4 8.1 30.0 22.1 10.0 16.8 54.1 19.3 10.2 12.5 12.2 41.6 9.6 32.9 14.2 22.5 10.1 14.9 18.6 43.2 35.7 8.8 31.4 7.9 26.4 16.4 42.7 5.9 23.4 24.4 13.1 20.6 29.2 16.7 13.1 20.6 26.9 9.3 31.7 8.3 14.3 23.3 CNTD1 "CNTD, FLJ40137" ENSG00000176563 "Cyclin N-terminal domain containing 1" Q8N815 17 42798800-42811587 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 13 "testis: 42.4" "Group enriched" "Detected in many" 5 "Early spermatids: 70.5;Late spermatids: 124.8;Respiratory ciliated cells: 47.0;Spermatocytes: 150.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 2.9;ASC diff: 1.6;SiHa: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA072363 Approved Nucleoplasm,Vesicles NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 78: Testis - Spermatogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm Vesicles "HPA072363: " "unprognostic (5.92e-2)" "unprognostic (1.99e-3)" "unprognostic (3.66e-2)" "unprognostic (2.13e-2)" "unprognostic (1.25e-1)" "unprognostic (6.29e-3)" "unprognostic (6.61e-2)" "unprognostic (1.09e-2)" "unprognostic (7.82e-2)" "unprognostic (6.18e-2)" "unprognostic (1.36e-2)" "unprognostic (2.07e-1)" "unprognostic (5.89e-7)" "unprognostic (1.52e-1)" "unprognostic (1.90e-1)" "unprognostic (2.35e-1)" "unprognostic (1.81e-4)" 0.3 0.2 0.9 0.0 0.9 0.1 1.8 1.2 1.9 0.1 0.1 0.8 0.1 0.1 1.4 0.0 0.7 0.0 0.1 0.9 1.0 1.5 0.0 0.5 0.0 1.0 0.9 0.4 1.0 0.3 0.0 0.1 0.9 1.3 1.9 0.2 0.1 0.1 0.1 0.1 0.2 0.1 0.8 0.1 3.3 42.4 0.8 0.0 0.3 0.6 0.0 0.2 0.0 1.9 2.9 0.3 0.2 0.5 1.6 0.4 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.2 0.2 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.1 0.2 0.0 0.0 0.0 1.5 0.1 0.3 0.0 0.8 0.0 0.0 0.7 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.9 0.9 1.2 1.9 0.9 1.0 1.0 0.9 0.9 0.8 0.8 1.9 1.2 3.2 4.6 2.3 1.0 0.4 0.5 0.4 0.0 1.7 5.5 2.2 1.1 1.5 2.1 0.0 0.0 0.3 1.2 1.4 5.9 0.2 70.5 5.4 1.7 0.8 0.0 2.7 1.9 0.4 0.4 1.9 4.1 1.6 6.3 0.2 0.4 1.1 0.3 6.7 1.6 5.3 4.1 1.0 0.7 124.8 2.5 1.1 0.0 0.0 0.2 1.0 0.0 2.0 1.1 0.4 0.4 1.2 0.7 5.6 0.9 0.5 47.0 0.7 6.6 1.0 1.7 150.2 17.1 0.0 0.6 0.3 0.9 0.5 2.7 2.3 CNTNAP1 "Caspr, CNTNAP, NRXN4, p190" ENSG00000108797 "Contactin associated protein 1" P78357 17 42682531-42699993 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Cell adhesion" "Disease variant, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 46.7" "Cell type enhanced" "Detected in many" "Astrocytes: 11.4;Bipolar cells: 15.6;Endometrial stromal cells: 15.5;Excitatory neurons: 45.6;Inhibitory neurons: 37.7" "Cancer enhanced" "Detected in all" "glioma: 10.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 43.5;TIME: 68.5;U-138 MG: 76.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011772 Approved Approved Nucleoplasm NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "HPA011772: AB_1079541" "unprognostic (4.04e-2)" "unprognostic (3.69e-1)" "unprognostic (2.37e-3)" "unprognostic (1.89e-1)" "unprognostic (5.02e-3)" "unprognostic (1.13e-1)" "unprognostic (3.19e-3)" "unprognostic (1.19e-1)" "unprognostic (2.59e-1)" "unprognostic (9.76e-3)" "unprognostic (1.99e-2)" "unprognostic (1.67e-1)" "prognostic unfavorable (4.16e-14)" "unprognostic (9.52e-3)" "unprognostic (2.27e-2)" "unprognostic (3.11e-2)" "unprognostic (7.37e-3)" 7.1 3.6 27.5 5.6 30.8 0.6 5.0 13.5 46.7 12.0 0.0 23.8 1.8 21.8 6.1 2.2 14.0 6.3 8.2 29.5 15.7 6.4 1.5 6.9 2.4 21.6 15.4 15.7 11.5 0.6 19.3 4.5 19.1 7.2 3.9 11.3 2.9 6.5 3.7 2.2 6.0 25.9 8.1 4.9 9.8 3.3 18.8 1.2 4.9 2.5 2.4 8.0 8.5 29.4 4.1 5.4 13.2 4.2 20.0 40.4 0.8 25.6 43.5 18.2 16.5 0.5 1.0 0.1 1.3 27.7 18.6 4.8 6.4 2.0 14.2 9.0 2.1 0.0 24.0 6.4 9.8 0.2 0.4 39.7 0.1 17.5 3.5 29.1 23.3 0.2 1.2 7.6 7.1 0.7 0.1 3.8 4.7 0.3 5.5 0.7 1.4 2.0 4.8 0.0 2.4 7.7 7.6 0.1 4.7 12.0 4.1 2.3 68.5 76.2 12.5 18.0 7.0 8.5 5.7 0.2 21.4 1.7 11.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 27.5 30.8 13.5 46.7 29.5 15.7 21.6 15.4 19.1 8.1 18.8 29.4 1.0 0.0 4.1 11.4 0.5 0.5 0.2 0.4 1.2 15.6 0.2 0.1 1.3 0.0 0.7 0.0 4.2 0.0 0.1 0.1 0.0 0.0 0.9 3.2 15.5 1.2 0.0 0.0 45.6 0.0 0.0 4.2 0.5 1.0 0.0 0.1 1.8 0.0 0.1 1.7 37.7 0.1 0.0 0.0 0.8 0.3 1.5 0.2 0.0 6.5 0.8 0.9 0.0 7.5 5.2 0.1 0.1 0.7 0.4 0.3 0.0 0.1 1.6 3.0 6.6 1.1 6.3 1.4 1.1 0.3 0.3 0.3 0.6 0.2 0.1 0.2 CNTNAP2 "Caspr2, KIAA0868, NRXN4" ENSG00000174469 "Contactin associated protein 2" Q9UHC6 7 146116002-148420998 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Autism, Autism spectrum disorder, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 20.7;retina: 14.4" "Group enriched" "Detected in many" 4 "Excitatory neurons: 3383.0;Inhibitory neurons: 6845.7" "Cancer enhanced" "Detected in many" "prostate cancer: 10.0" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "naive B-cell: 2.5" "Lineage enriched" "Detected in single" 25 "B-cells: 2.5" "Cell line enhanced" "Detected in some" "AF22: 8.0;CACO-2: 6.7;NTERA-2: 12.0;SCLC-21H: 21.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002739 Enhanced NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA002739: AB_1078545" "unprognostic (2.49e-2)" "unprognostic (1.49e-2)" "unprognostic (4.05e-1)" "unprognostic (3.08e-3)" "unprognostic (1.77e-1)" "unprognostic (2.29e-1)" "unprognostic (2.51e-2)" "unprognostic (1.45e-2)" "unprognostic (1.18e-1)" "unprognostic (2.19e-1)" "unprognostic (3.67e-2)" "unprognostic (2.68e-1)" "unprognostic (1.41e-1)" "unprognostic (1.78e-1)" "unprognostic (1.37e-1)" "unprognostic (2.33e-1)" "unprognostic (1.00e-3)" 0.2 0.8 10.0 0.2 13.8 0.0 0.6 1.4 20.7 0.1 0.0 0.8 0.0 0.0 0.0 0.4 0.6 0.0 0.2 5.6 5.7 0.1 1.9 0.0 0.4 5.7 0.5 1.1 0.2 0.3 3.8 0.5 3.8 4.1 0.4 14.4 0.1 0.1 0.0 0.0 0.9 0.0 0.0 0.4 0.2 0.5 1.8 3.7 0.3 0.0 0.2 0.1 0.1 0.0 0.0 0.0 8.0 3.1 0.0 0.0 2.8 0.0 0.0 0.0 0.0 6.7 0.1 0.0 0.0 0.2 0.0 2.0 1.7 0.6 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.1 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 12.0 1.4 0.0 0.0 0.0 2.2 0.0 0.0 21.5 1.4 0.0 0.0 0.0 0.3 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 10.0 13.8 1.4 20.7 5.6 5.7 5.7 0.5 3.8 0.0 1.8 0.0 0.1 0.0 0.0 65.6 9.3 0.1 0.3 15.5 1.8 33.9 0.3 0.0 1.2 7.2 4.1 0.0 2.1 40.8 0.0 1.8 0.0 1.4 7.2 0.6 0.0 0.6 2.4 0.0 3383.0 0.7 6.8 1.1 0.5 0.7 0.0 0.2 0.0 8.9 3.3 1031.4 6845.7 3.9 0.0 0.6 2.0 2.7 1.2 0.4 0.0 180.8 0.2 8.2 1.0 429.3 914.7 4.1 2.1 0.0 0.3 7.4 4.7 0.5 0.9 16.7 0.0 0.0 0.9 2.4 12.0 9.1 0.0 6.3 0.0 1.2 6.8 0.2 COA4 "CHCHD8, CMC3, E2IG2" ENSG00000181924 "Cytochrome c oxidase assembly factor 4 homolog" Q9NYJ1 11 73872667-73876901 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040126 Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Mitochondria" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Nucleoli fibrillar center" Mitochondria "HPA040126: AB_10795415" "unprognostic (7.30e-2)" "unprognostic (8.69e-2)" "unprognostic (2.09e-1)" "unprognostic (2.60e-2)" "unprognostic (1.87e-1)" "unprognostic (1.40e-2)" "unprognostic (3.64e-3)" "unprognostic (1.49e-1)" "unprognostic (2.22e-2)" "prognostic favorable (3.87e-4)" "unprognostic (1.31e-2)" "unprognostic (3.97e-2)" "prognostic unfavorable (2.14e-4)" "unprognostic (2.51e-1)" "unprognostic (1.89e-1)" "unprognostic (1.25e-1)" "unprognostic (8.17e-2)" 45.1 96.2 46.9 36.8 52.5 25.4 39.0 51.6 52.0 37.1 46.2 44.5 49.0 35.8 32.5 48.0 40.2 40.3 63.1 46.0 49.4 70.4 99.7 31.3 47.3 51.0 50.4 37.8 46.5 49.6 34.2 37.6 51.0 45.1 42.2 15.7 42.7 36.2 72.2 33.1 49.6 32.4 50.6 37.1 41.6 31.6 50.3 32.3 55.7 55.9 36.0 54.6 37.4 56.9 106.4 201.9 80.2 119.0 70.6 86.6 79.3 107.4 75.5 126.0 107.2 147.4 132.5 91.3 214.7 90.2 99.9 105.7 124.2 146.1 98.3 120.6 115.1 156.3 118.1 141.8 130.5 107.2 115.0 109.4 136.1 207.0 136.6 70.9 120.0 87.0 135.3 87.5 118.3 210.8 83.7 168.1 104.3 422.7 205.9 96.2 174.3 244.0 137.5 101.3 72.5 121.3 99.0 110.7 295.3 78.8 162.3 108.0 83.8 102.8 91.7 212.9 142.8 103.3 125.1 313.1 57.0 132.0 121.4 18.5 49.6 12.7 35.9 52.2 47.0 58.1 42.0 37.8 61.1 48.5 44.6 48.2 3.4 43.1 51.4 80.2 47.7 38.6 46.9 52.5 51.6 52.0 46.0 49.4 51.0 50.4 51.0 50.6 50.3 56.9 48.9 35.3 36.0 6.8 48.6 53.5 75.7 89.7 47.8 19.5 64.3 86.1 66.7 85.8 55.5 55.2 22.9 168.8 36.7 97.8 129.1 89.2 37.3 77.2 90.9 49.7 72.6 68.3 3.6 94.9 111.3 54.2 69.3 72.0 62.1 83.9 33.2 184.1 97.5 18.5 5.8 98.6 28.5 44.8 34.2 13.3 55.0 44.7 28.4 2.8 55.2 67.5 49.4 8.5 18.8 98.2 85.1 38.4 47.3 139.5 174.2 266.2 47.1 18.5 6.6 81.6 51.0 78.7 34.2 86.3 51.3 122.3 39.9 150.7 121.2 98.7 COL11A2 "DFNA13, DFNB53, HKE5" ENSG00000204248 "Collagen type XI alpha 2 chain" P13942 6 33162681-33192499 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Deafness, Disease variant, Dwarfism, Non-syndromic deafness, Stickler syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "pituitary gland: 23.5;testis: 8.1" "Cell type enhanced" "Detected in some" "Astrocytes: 8.5;Early spermatids: 10.8;Muller glia cells: 5.2;Oligodendrocytes: 6.7" "Cancer enriched" "Detected in many" 8 "melanoma: 13.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA 2100000 "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 29: Early spermatids - Spermatogenesis" "unprognostic (4.62e-1)" "unprognostic (8.69e-2)" "unprognostic (1.65e-4)" "unprognostic (5.15e-3)" "unprognostic (1.14e-1)" "unprognostic (1.69e-1)" "unprognostic (1.04e-2)" "unprognostic (9.67e-2)" "unprognostic (2.05e-2)" "unprognostic (4.47e-2)" "unprognostic (1.22e-1)" "unprognostic (3.41e-3)" "unprognostic (2.26e-6)" "unprognostic (8.27e-2)" "unprognostic (2.17e-1)" "unprognostic (1.88e-1)" "unprognostic (5.96e-2)" 1.0 0.3 0.3 0.0 0.6 0.0 0.9 0.5 0.6 1.6 0.0 0.7 0.2 1.2 0.2 0.5 0.9 0.1 1.8 0.3 0.3 1.3 0.8 1.0 0.0 0.5 0.4 1.1 0.6 0.1 23.5 0.0 0.5 1.3 0.0 0.1 0.8 0.1 1.3 0.6 0.7 0.1 0.5 1.2 0.7 8.1 0.5 0.3 3.5 0.7 0.0 0.6 0.9 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.4 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.3 0.1 0.0 0.2 0.2 0.0 0.0 0.6 0.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.5 0.6 0.3 0.3 0.5 0.4 0.5 0.5 0.5 0.8 2.6 0.0 0.0 8.5 0.1 1.5 0.2 0.1 1.8 2.8 1.2 1.8 2.3 0.0 0.1 0.0 4.2 0.0 0.6 0.3 0.0 0.1 10.8 0.2 0.6 1.5 0.0 0.0 4.2 0.0 0.0 0.3 0.0 0.5 0.0 0.6 4.6 0.2 0.2 0.0 3.7 0.1 0.0 0.6 0.4 1.9 0.0 0.3 1.8 1.0 0.0 5.2 0.0 3.5 6.7 0.1 0.6 0.4 0.8 0.2 0.0 0.1 0.0 1.1 0.0 0.7 1.8 0.9 2.1 0.7 1.1 0.0 0.4 0.2 0.5 0.1 COL15A1 ENSG00000204291 "Collagen type XV alpha 1 chain" P39059 9 98943179-99070792 "Plasma proteins, Predicted secreted proteins" "Angiogenesis, Cell adhesion, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 229.2" "Cell type enhanced" "Detected in many" "Adipocytes: 307.0;Endothelial cells: 190.5;Fibroblasts: 202.3;Leydig cells: 326.8;Peritubular cells: 483.3;Theca cells: 333.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 26.4;BJ hTERT+: 55.6;HDLM-2: 24.5;K-562: 18.8;U-2197: 45.6;U-87 MG: 20.6;WM-115: 31.0" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 7 "spinal cord: 44.3" "HPA017913, HPA017915" Enhanced Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 28000000 "Cluster 28: Placenta - Pregnancy" "Cluster 18: U-2197 - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Endoplasmic reticulum" "HPA017913: AB_1847099, HPA017915: AB_1847100" "unprognostic (4.30e-1)" "unprognostic (1.44e-1)" "unprognostic (1.41e-1)" "unprognostic (2.22e-2)" "unprognostic (2.09e-1)" "unprognostic (1.09e-2)" "prognostic favorable (5.47e-4)" "unprognostic (3.08e-2)" "unprognostic (1.05e-1)" "unprognostic (2.29e-1)" "unprognostic (1.84e-1)" "unprognostic (7.87e-2)" "unprognostic (1.20e-3)" "unprognostic (3.66e-3)" "unprognostic (8.98e-2)" "unprognostic (6.98e-2)" "prognostic unfavorable (3.08e-4)" 84.7 36.9 0.6 50.6 0.9 0.1 46.7 0.8 1.0 31.2 4.0 44.5 12.9 53.8 19.2 26.9 17.3 42.8 58.0 0.4 0.8 12.9 1.0 11.1 10.4 0.6 0.9 23.2 26.8 11.8 6.0 229.2 0.7 21.6 16.3 0.0 35.9 14.3 56.5 15.1 17.7 108.9 0.6 3.7 27.3 27.0 2.4 13.0 21.1 34.4 8.6 42.1 15.1 0.7 0.0 0.0 0.1 0.0 4.6 2.6 0.1 26.4 55.6 1.4 0.5 0.0 0.0 0.2 0.7 5.8 0.2 0.1 0.0 0.0 0.2 24.5 0.0 0.3 12.9 0.0 1.1 0.4 2.5 7.6 0.0 6.0 0.2 0.0 0.0 0.0 18.8 0.0 2.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 14.7 0.2 0.0 0.0 0.1 0.1 0.8 3.9 7.4 0.3 0.2 0.6 0.0 0.1 0.6 45.6 0.5 0.2 0.0 0.0 20.6 0.2 31.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.9 0.8 1.0 0.4 0.8 0.6 0.9 0.7 0.6 2.4 0.7 307.0 0.0 0.0 0.7 0.5 19.5 0.1 0.0 5.2 0.0 2.6 4.1 8.1 0.0 0.0 0.0 0.0 3.8 1.8 0.0 0.0 2.4 5.7 3.9 103.4 190.5 0.0 0.0 0.4 0.8 3.7 202.3 0.5 2.2 0.0 0.3 0.0 0.0 7.6 0.0 2.9 0.0 0.0 0.3 27.2 22.5 326.8 3.1 17.8 46.9 0.6 0.0 1.0 1.0 0.3 0.6 0.0 483.3 0.3 1.2 0.0 0.5 0.0 0.0 13.1 107.8 52.8 1.9 1.2 1.3 16.3 7.7 2.1 333.4 0.0 0.7 COL4A1 ENSG00000187498 "Collagen type IV alpha 1 chain" P02462 13 110148963-110307157 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 900.3" "Cell type enhanced" "Detected in many" "Adipocytes: 401.4;Endometrial stromal cells: 312.2;Endothelial cells: 385.9;Extravillous trophoblasts: 672.4;Sertoli cells: 506.2;Smooth muscle cells: 415.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.4" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.4" "Cell line enhanced" "Detected in many" "ASC diff: 501.6;EFO-21: 915.3;TIME: 331.3" "Low region specificity" "Detected in all" CAB001695 Approved "Secreted to extracellular matrix" NA NA 75000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 28: Placenta - Pregnancy" "Cluster 38: EFO-21 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" "CAB001695: " "unprognostic (3.82e-2)" "prognostic unfavorable (4.67e-4)" "unprognostic (2.27e-1)" "unprognostic (1.02e-1)" "unprognostic (3.28e-1)" "unprognostic (2.40e-1)" "unprognostic (1.10e-1)" "unprognostic (6.51e-3)" "unprognostic (1.06e-2)" "unprognostic (9.79e-2)" "unprognostic (1.73e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (1.30e-7)" "unprognostic (1.47e-3)" "unprognostic (1.72e-2)" "unprognostic (1.58e-1)" "unprognostic (1.16e-2)" 348.4 33.6 10.8 135.9 5.2 0.4 130.4 3.7 9.0 65.7 8.9 108.5 24.8 105.3 14.8 40.8 64.1 116.8 81.9 12.6 5.2 53.4 22.1 137.0 27.7 9.1 7.0 27.0 36.0 36.3 12.8 900.3 7.5 53.6 30.4 1.8 19.0 85.6 40.1 25.2 43.4 312.7 6.8 76.3 50.1 10.7 13.7 10.7 54.7 47.0 11.1 120.8 38.2 6.9 40.0 15.2 195.9 0.3 501.6 148.9 274.9 246.2 59.5 134.0 65.3 4.2 0.8 0.1 915.3 46.2 59.7 26.8 0.0 55.8 30.3 1.3 29.5 0.2 28.2 0.0 142.8 0.0 0.4 49.7 8.9 132.8 59.4 212.8 207.7 0.1 0.3 0.2 31.1 0.1 0.1 0.8 28.1 0.2 3.6 0.4 58.6 0.1 278.8 0.0 1.4 29.8 0.1 0.4 61.0 192.4 0.1 13.9 331.3 39.9 121.4 1.0 97.4 0.3 1.8 3.9 0.4 0.7 297.0 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.4 0.2 0.0 0.1 0.0 0.0 10.8 5.2 3.7 9.0 12.6 5.2 9.1 7.0 7.5 6.8 13.7 6.9 401.4 41.7 8.9 5.2 1.9 14.0 9.7 8.5 2.8 1.0 3.5 16.5 41.1 10.0 0.9 23.9 0.0 49.7 0.5 0.1 1.9 22.6 0.7 19.8 312.2 385.9 0.0 0.0 10.5 0.2 672.4 211.8 1.5 48.7 1.3 215.8 134.6 1.3 27.7 0.0 18.9 0.5 0.0 4.4 19.2 2.8 38.5 4.2 30.2 36.5 0.6 2.5 0.0 1.0 0.9 0.6 0.1 109.4 0.5 6.2 0.5 26.7 2.8 0.4 506.2 142.8 415.1 1.2 5.0 0.8 15.2 45.0 4.2 45.9 0.6 2.2 COP1 "CFAP78, FAP78, FLJ10416, RFWD2, RNF200" ENSG00000143207 "COP1 E3 ubiquitin ligase" Q8NHY2 1 175944831-176207286 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 28.1;Extravillous trophoblasts: 33.5;Syncytiotrophoblasts: 31.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 15: RT4 - Unknown function" "Cluster 7: Non-specific - Mitochondria" "unprognostic (1.99e-1)" "unprognostic (3.76e-2)" "unprognostic (4.17e-2)" "prognostic unfavorable (3.96e-4)" "unprognostic (2.95e-2)" "unprognostic (4.33e-1)" "unprognostic (2.01e-2)" "unprognostic (1.10e-1)" "unprognostic (2.78e-2)" "unprognostic (3.52e-2)" "unprognostic (9.24e-2)" "unprognostic (1.67e-1)" "unprognostic (1.33e-2)" "unprognostic (6.68e-2)" "unprognostic (7.01e-2)" "unprognostic (1.59e-1)" "unprognostic (1.55e-1)" 14.2 9.5 5.9 12.0 7.1 16.8 12.7 11.4 9.1 12.1 8.4 18.1 13.8 11.8 9.8 14.2 9.4 9.5 9.8 8.5 5.9 12.4 16.6 12.5 15.7 4.6 5.0 8.7 13.2 10.5 8.0 11.2 5.0 10.1 16.7 8.6 13.1 8.5 13.6 17.5 13.9 11.0 5.7 16.7 13.7 15.6 6.1 14.9 10.6 7.4 16.8 14.7 11.9 8.8 35.3 17.5 22.1 13.8 23.0 22.6 56.1 21.7 22.0 17.7 18.6 30.0 28.1 59.4 25.8 20.9 18.9 32.3 16.9 27.0 17.7 23.7 17.0 22.6 19.4 28.0 18.9 49.2 33.0 16.8 28.9 17.6 19.8 17.9 26.6 21.7 43.9 24.9 24.8 42.5 27.0 28.2 47.4 55.8 2.0 26.1 20.4 40.2 26.8 93.7 22.6 41.6 27.8 44.9 35.9 37.4 32.1 69.1 40.4 19.4 16.1 28.3 23.4 35.3 62.7 49.8 19.1 26.7 26.9 8.5 3.0 12.0 1.9 3.7 1.4 1.7 2.0 1.4 2.1 1.5 2.7 2.0 14.1 0.6 3.4 1.1 1.7 1.0 5.9 7.1 11.4 9.1 8.5 5.9 4.6 5.0 5.0 5.7 6.1 8.8 15.8 22.4 14.5 0.0 4.4 0.0 0.0 0.0 0.0 0.0 15.4 10.9 0.0 0.0 3.1 9.2 0.0 28.1 12.2 0.0 21.5 14.8 0.0 17.9 14.6 7.2 0.0 0.0 0.0 22.7 33.5 7.4 0.0 20.1 7.6 18.1 0.0 0.0 22.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 0.0 0.0 10.3 0.0 0.0 0.0 0.0 21.8 0.0 0.0 3.1 0.0 0.0 22.1 4.4 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 31.3 6.7 13.8 0.0 0.0 COQ5 MGC4767 ENSG00000110871 "Coenzyme Q5, methyltransferase" Q5HYK3 12 120503279-120534434 "Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Ubiquinone biosynthesis" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049487 Approved Uncertain Nucleoli,Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 39: Non-specific - Basic cellular processes" Nucleoli Mitochondria "HPA049487: AB_2680789" "unprognostic (1.46e-1)" "unprognostic (1.99e-2)" "unprognostic (1.32e-1)" "unprognostic (6.30e-3)" "unprognostic (2.00e-1)" "unprognostic (1.66e-1)" "unprognostic (1.88e-1)" "unprognostic (1.60e-1)" "unprognostic (2.01e-2)" "unprognostic (6.20e-2)" "unprognostic (1.62e-1)" "unprognostic (8.37e-2)" "unprognostic (3.79e-2)" "unprognostic (2.02e-1)" "unprognostic (7.73e-2)" "unprognostic (2.00e-2)" "unprognostic (3.88e-2)" 22.7 29.9 22.3 15.9 25.3 11.3 24.1 24.5 29.0 19.7 26.7 24.7 23.4 17.9 23.0 20.4 22.2 14.4 40.7 22.1 23.4 38.9 60.7 15.4 23.3 24.9 24.2 20.5 20.6 21.6 18.1 23.3 24.8 18.9 24.7 26.3 22.4 15.8 98.5 17.6 20.0 18.2 22.8 21.1 19.3 24.7 24.3 22.3 25.7 69.2 23.4 17.2 17.6 29.5 35.7 56.1 49.2 14.2 63.5 48.5 33.7 42.3 27.6 42.5 26.9 22.5 29.2 35.6 48.8 44.7 29.9 37.7 44.2 47.2 43.3 45.4 26.3 47.4 35.0 37.8 51.8 52.2 28.7 46.8 50.2 40.0 46.1 66.0 38.0 67.5 47.4 25.3 49.7 46.9 30.3 60.0 43.2 25.4 43.2 55.9 49.8 52.0 55.2 26.7 37.0 29.8 30.7 15.5 58.3 51.2 77.8 42.6 37.9 29.1 33.4 21.8 28.5 53.9 48.5 40.5 33.3 48.9 35.8 28.6 44.3 32.3 39.7 44.9 39.0 45.6 42.4 43.2 61.0 52.7 56.8 45.5 9.3 60.6 43.5 40.3 57.2 54.4 22.3 25.3 24.5 29.0 22.1 23.4 24.9 24.2 24.8 22.8 24.3 29.5 14.4 12.8 12.8 7.2 15.5 7.8 11.5 33.5 10.8 12.6 17.5 15.2 30.5 18.6 18.1 14.7 14.6 73.0 12.9 16.1 46.9 32.3 59.8 17.8 12.1 15.4 15.0 17.5 5.7 20.0 45.6 16.5 11.7 11.3 17.2 24.0 15.4 42.4 46.3 5.0 7.8 17.0 22.4 12.8 10.1 23.1 16.4 13.6 23.2 3.7 29.0 18.0 23.7 6.6 17.5 11.0 23.9 18.8 11.0 11.2 35.8 66.7 22.4 15.6 6.6 16.3 14.4 34.7 14.8 14.3 8.9 58.3 15.0 32.8 28.1 10.9 CORO1A "coronin-1, HCORO1, p57" ENSG00000102879 "Coronin 1A" P31146 16 30182827-30189076 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 568.8;lymphoid tissue: 583.8" "Cell type enhanced" "Detected in many" "B-cells: 523.9;dendritic cells: 588.7;Hofbauer cells: 494.4;Kupffer cells: 395.8;Macrophages: 342.7;monocytes: 583.7;NK-cells: 968.1;T-cells: 663.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 924.0;HL-60: 645.7;HMC-1: 1086.7;JURKAT: 603.0;MOLT-4: 632.5;NB-4: 771.8;RPMI-8226: 980.9;U-698: 618.2;U-937: 829.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046473, HPA051132" Enhanced Approved Cytosol NA NA 45000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "CAB046473: AB_10602363, HPA051132: AB_2681355" "unprognostic (4.17e-3)" "unprognostic (3.64e-3)" "unprognostic (3.86e-2)" "prognostic favorable (6.91e-4)" "unprognostic (2.41e-1)" "prognostic favorable (4.42e-4)" "unprognostic (1.99e-2)" "unprognostic (8.27e-3)" "unprognostic (8.26e-3)" "unprognostic (4.30e-1)" "unprognostic (1.54e-1)" "unprognostic (2.25e-1)" "prognostic unfavorable (5.74e-7)" "unprognostic (2.55e-1)" "unprognostic (2.37e-2)" "unprognostic (7.16e-2)" "unprognostic (2.01e-1)" 29.1 20.8 34.4 306.4 37.1 568.8 11.2 24.9 52.0 10.6 23.6 26.8 44.3 10.0 3.1 22.5 17.9 45.0 11.3 36.9 31.9 11.5 13.1 49.5 583.8 37.6 32.0 6.4 8.4 4.3 9.3 18.4 32.2 11.4 15.3 0.9 32.9 7.3 6.7 17.6 111.0 22.2 35.8 321.4 49.0 4.8 33.9 257.6 12.7 8.8 309.1 57.6 10.4 50.0 3.1 3.6 10.9 21.5 0.1 0.1 6.1 2.6 0.7 5.4 3.0 0.7 6.9 924.0 6.1 0.9 1.5 4.4 5.2 10.8 1.3 302.3 2.5 97.9 0.5 15.0 1.7 645.7 1086.7 2.8 0.0 4.3 0.5 0.4 2.0 603.0 1.5 467.6 3.4 80.7 632.5 771.8 4.0 3.1 6.4 340.0 17.5 980.9 1.3 5.1 17.3 13.0 2.2 110.7 2.0 0.2 1.9 373.0 1.6 4.0 9.0 2.7 3.1 348.5 497.7 618.2 3.0 829.6 6.3 797.2 773.6 2671.1 637.5 859.7 597.8 505.5 567.3 625.6 843.2 512.0 537.1 566.2 1318.9 531.0 898.0 482.1 858.7 1647.2 34.4 37.1 24.9 52.0 36.9 31.9 37.6 32.0 32.2 35.8 33.9 50.0 6.3 22.4 32.5 0.3 523.9 11.3 1.2 3.2 2.2 1.2 4.7 5.5 1.5 17.2 6.0 1.8 0.0 4.6 588.7 2.3 0.0 3.5 0.5 1.1 2.0 12.3 6.0 60.2 3.3 0.9 17.4 9.5 18.8 1.3 83.7 0.6 21.8 4.8 494.4 0.0 1.7 2.2 6.1 395.8 197.9 1.2 0.6 342.7 32.0 4.7 583.7 0.8 968.1 1.5 0.4 11.1 47.5 0.0 201.4 0.8 1.0 4.8 3.5 0.9 6.6 2.9 5.1 0.1 0.9 2.4 9.1 4.9 663.0 2.7 3.3 0.9 CPEB1 "CPEB, FLJ13203" ENSG00000214575 "Cytoplasmic polyadenylation element binding protein 1" Q9BZB8 15 82543201-82648861 "Predicted intracellular proteins" "mRNA processing, Translation regulation" "Activator, Repressor, Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 33.6;testis: 32.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 70.0;Inhibitory neurons: 44.3;Oligodendrocytes: 196.5;Spermatocytes: 34.1;Spermatogonia: 62.3" "Cancer enriched" "Detected in some" 6 "testis cancer: 14.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD8 T-cell: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "SK-MEL-30: 37.9;U-2197: 106.0;U-87 MG: 39.1" HPA040396 Supported Nucleoplasm,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Cytosol" "HPA040396: AB_2676960" "unprognostic (3.97e-2)" "unprognostic (1.01e-1)" "unprognostic (1.44e-2)" "unprognostic (1.77e-3)" "unprognostic (1.17e-1)" "unprognostic (2.36e-1)" "unprognostic (1.98e-1)" "unprognostic (7.74e-2)" "unprognostic (3.90e-2)" "unprognostic (2.07e-2)" "unprognostic (1.35e-2)" "unprognostic (7.51e-3)" "unprognostic (1.97e-3)" "unprognostic (9.50e-3)" "unprognostic (8.17e-2)" "unprognostic (2.05e-2)" "unprognostic (5.37e-4)" 2.8 5.0 10.4 1.3 18.6 0.2 2.5 20.3 18.6 9.3 4.5 6.8 1.2 4.2 7.9 3.6 8.3 4.0 2.9 12.7 17.0 1.2 0.2 1.6 0.5 21.3 21.7 14.3 1.3 0.8 21.8 0.3 24.0 2.3 2.4 4.5 1.5 3.7 2.4 1.9 2.5 3.4 15.0 0.6 2.5 32.4 20.4 0.4 2.3 10.5 0.5 7.7 6.1 33.6 0.1 3.6 0.3 0.4 2.6 0.2 0.1 2.8 0.3 1.8 1.4 0.2 0.1 0.0 6.3 1.1 19.5 0.1 5.1 0.0 0.4 0.0 4.2 0.1 0.1 0.1 1.8 0.1 2.3 1.4 0.0 3.5 0.0 0.2 0.0 7.6 8.9 0.2 1.3 0.2 0.6 0.1 8.2 0.1 1.0 0.0 0.2 0.1 0.0 0.1 10.5 2.4 9.2 0.5 37.9 11.2 0.1 1.1 0.1 18.9 7.5 106.0 6.0 5.3 14.3 1.4 39.1 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.5 0.0 0.1 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.1 10.4 18.6 20.3 18.6 12.7 17.0 21.3 21.7 24.0 15.0 20.4 33.6 0.3 0.0 0.0 19.6 0.1 0.8 0.3 0.0 0.0 11.5 0.6 0.3 1.9 0.0 0.0 0.0 10.4 0.0 0.1 0.1 0.0 0.1 12.6 0.5 1.4 0.2 0.0 0.0 70.0 0.0 0.0 5.9 0.5 0.1 1.3 0.3 0.4 0.0 0.3 11.8 44.3 0.0 0.0 0.0 0.8 20.0 4.1 0.4 5.4 10.3 0.1 5.2 0.0 10.1 196.5 0.1 0.0 2.2 0.2 0.5 0.0 0.4 2.2 4.3 6.6 1.9 1.8 34.1 62.3 0.0 0.6 0.1 0.4 0.0 0.0 0.1 CPNE6 ENSG00000100884 "Copine 6" O95741 14 24070837-24078100 "Plasma proteins, Predicted intracellular proteins" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 54.3;retina: 16.4" "Cell type enhanced" "Detected in some" "Astrocytes: 15.3;Bipolar cells: 26.3;Horizontal cells: 32.0;Inhibitory neurons: 11.4;Late spermatids: 18.1" "Cancer enhanced" "Detected in single" "glioma: 1.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-266/84: 1.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031636, HPA076665" Enhanced NA NA "Cluster 65: Brain - Ion transport" "Cluster 16: U-266 - Nucleosome" "Cluster 62: Horizontal cells - Visual perception" "HPA031636: AB_10601203, HPA076665: " "unprognostic (1.02e-2)" "unprognostic (3.26e-4)" "unprognostic (1.64e-1)" "unprognostic (5.66e-5)" "unprognostic (3.51e-3)" "unprognostic (2.53e-2)" "unprognostic (2.49e-2)" "unprognostic (1.09e-3)" "unprognostic (1.71e-1)" "unprognostic (1.67e-1)" "unprognostic (2.30e-2)" "unprognostic (3.65e-2)" "unprognostic (1.32e-1)" "unprognostic (1.01e-2)" "unprognostic (5.79e-2)" "unprognostic (4.50e-2)" "unprognostic (2.71e-1)" 0.2 0.2 42.1 0.2 37.7 0.2 0.0 20.0 41.1 0.2 12.2 1.5 2.5 0.2 0.3 1.7 0.3 0.0 0.2 54.3 24.9 7.0 2.1 0.1 0.0 31.4 23.2 0.1 0.0 0.0 8.0 0.0 32.7 2.8 0.5 16.4 0.0 12.3 0.1 0.4 3.4 0.3 20.8 0.0 0.4 0.5 31.3 0.1 0.2 0.1 0.0 0.7 0.4 26.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 42.1 37.7 20.0 41.1 54.3 24.9 31.4 23.2 32.7 20.8 31.3 26.0 0.0 0.0 0.0 15.3 0.0 0.1 0.0 0.0 0.0 26.3 0.0 0.0 1.7 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.1 0.0 0.0 6.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.0 11.4 0.2 0.0 0.0 0.0 18.1 0.6 0.0 0.0 1.0 0.0 1.4 0.0 1.5 0.8 0.0 0.0 0.0 0.0 0.3 6.5 2.4 0.0 3.8 0.0 0.0 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 CPNE9 KIAA4217 ENSG00000144550 "Copine family member 9" Q8IYJ1 3 9703826-9729908 "Predicted intracellular proteins" Differentiation "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "brain: 69.2" "Cell type enhanced" "Detected in some" "Early spermatids: 12.9;Excitatory neurons: 28.2;Inhibitory neurons: 8.0;Late spermatids: 61.3" "Cancer enriched" "Detected in single" 4 "testis cancer: 1.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "intermediate monocyte: 1.0" "Lineage enhanced" "Detected in single" "monocytes: 1.0" "Cell line enhanced" "Detected in some" "Daudi: 2.3;U-937: 2.0" "Low region specificity" "Detected in all" HPA060813 Approved "Plasma membrane,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "Plasma membrane" "HPA060813: " "unprognostic (2.96e-1)" "unprognostic (4.75e-2)" "unprognostic (1.34e-1)" "unprognostic (5.04e-3)" "unprognostic (1.10e-1)" "unprognostic (1.96e-1)" "unprognostic (2.13e-3)" "unprognostic (1.03e-2)" "unprognostic (3.19e-2)" "unprognostic (1.06e-1)" "unprognostic (1.20e-4)" "unprognostic (2.67e-2)" "unprognostic (5.44e-4)" "unprognostic (1.47e-2)" "unprognostic (8.59e-2)" "unprognostic (3.45e-1)" "unprognostic (7.48e-2)" 0.1 2.1 10.9 0.2 7.1 1.2 0.1 12.1 23.6 0.1 0.0 0.4 0.3 0.1 0.0 0.1 0.1 0.1 0.1 5.8 19.6 0.2 0.0 0.3 0.2 69.2 19.8 0.1 0.1 0.1 5.3 0.1 65.0 0.1 0.1 1.1 0.1 0.2 0.0 1.7 0.3 0.2 4.2 0.2 0.3 1.3 39.6 0.1 0.1 0.0 0.1 0.1 0.1 12.9 0.0 0.3 0.1 0.0 0.3 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.1 2.3 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.2 0.7 0.2 0.0 0.0 0.2 0.3 0.3 0.0 0.3 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.0 0.0 0.0 0.2 0.0 0.2 0.6 0.5 0.0 0.0 0.2 0.4 0.7 0.9 0.0 0.0 0.0 0.3 0.0 0.1 0.7 0.4 0.3 2.0 0.1 0.0 0.3 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.4 0.0 0.1 10.9 7.1 12.1 23.6 5.8 19.6 69.2 19.8 65.0 4.2 39.6 12.9 0.1 0.0 0.0 2.0 0.0 0.3 0.0 0.0 0.6 0.8 0.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 12.9 0.1 0.1 0.1 0.0 0.0 28.2 0.2 0.0 0.3 0.0 0.4 0.0 0.0 0.4 0.0 1.9 0.0 8.0 0.0 0.0 0.8 0.3 61.3 0.0 0.8 0.0 3.7 0.0 0.7 0.0 2.0 2.2 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.0 0.2 0.2 0.9 0.7 0.2 0.4 0.0 0.1 0.0 0.1 0.0 CPPED1 "CSTP1, FLJ11151" ENSG00000103381 "Calcineurin like phosphoesterase domain containing 1" Q9BRF8 16 12659799-12803887 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 105.2;monocytes: 127.4;Syncytiotrophoblasts: 131.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 674.2" "Group enriched" "Detected in all" 28 "dendritic cells: 168.5;granulocytes: 674.2;monocytes: 320.8" "Cell line enhanced" "Detected in many" "Hep G2: 144.2;HMC-1: 129.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040938, HPA041970" Uncertain Supported "Plasma membrane,Cytosol" No No 470000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol "Plasma membrane" "HPA040938: AB_10673443, HPA041970: AB_2677774" "prognostic unfavorable (9.72e-4)" "unprognostic (1.70e-1)" "unprognostic (2.04e-3)" "unprognostic (1.05e-2)" "unprognostic (1.13e-3)" "unprognostic (3.86e-2)" "unprognostic (1.35e-1)" "unprognostic (8.67e-2)" "unprognostic (1.23e-1)" "unprognostic (3.26e-2)" "unprognostic (6.26e-2)" "unprognostic (3.64e-1)" "prognostic favorable (1.62e-9)" "unprognostic (5.05e-2)" "unprognostic (1.25e-1)" "unprognostic (2.48e-3)" "unprognostic (2.40e-2)" 12.5 9.4 9.1 19.3 14.1 14.0 8.2 13.0 11.4 11.0 7.3 13.3 21.3 7.9 5.1 25.2 7.1 11.2 10.1 8.3 13.3 33.7 34.4 13.7 11.7 14.0 13.1 7.6 4.8 3.9 4.1 18.5 14.4 11.1 14.8 3.7 13.1 8.6 8.2 6.5 21.4 12.9 11.3 29.8 8.7 15.5 12.2 9.2 13.2 9.6 16.6 11.5 8.8 17.3 5.0 29.7 3.3 7.7 12.0 25.3 0.5 54.1 14.5 28.4 23.1 14.5 15.2 7.3 54.6 39.6 12.5 0.4 0.0 13.5 29.3 17.0 8.2 62.5 4.2 144.2 7.4 0.1 129.9 25.4 3.0 2.5 20.2 0.1 43.1 9.9 22.1 4.3 70.4 6.3 5.6 29.1 8.7 2.4 4.2 11.9 18.8 15.6 43.0 9.4 15.3 10.0 0.2 48.5 20.0 15.3 10.5 13.7 65.0 40.6 8.5 0.2 0.1 0.1 1.0 11.6 9.1 31.7 8.8 57.1 224.0 146.1 9.1 320.0 7.8 10.8 7.6 10.0 168.5 8.4 2.4 5.7 674.2 13.5 320.8 41.1 13.8 129.7 9.1 14.1 13.0 11.4 8.3 13.3 14.0 13.1 14.4 11.3 12.2 17.3 12.3 9.6 16.7 8.1 8.7 4.6 3.4 4.9 4.6 3.3 4.7 4.7 10.7 10.0 11.4 14.7 8.4 105.2 18.5 9.2 60.7 43.1 3.6 5.3 13.5 16.7 6.0 31.7 13.1 12.8 15.6 12.6 4.1 9.4 54.4 8.1 7.5 45.8 47.1 10.1 10.2 9.3 6.1 80.3 30.7 4.1 15.5 59.0 7.2 30.0 127.4 13.5 8.2 21.1 70.9 31.9 18.3 24.0 4.4 3.2 40.6 66.0 13.4 6.1 26.3 17.6 11.9 2.5 9.9 14.8 4.5 131.9 8.3 13.6 15.4 1.7 CPSF2 "CPSF100, KIAA1367" ENSG00000165934 "Cleavage and polyadenylation specific factor 2" Q9P2I0 14 92121969-92172145 "Plasma proteins, Predicted intracellular proteins" "mRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024238 Supported Approved Nucleoplasm,Vesicles NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Vesicles "HPA024238: AB_1847200" "unprognostic (2.31e-1)" "unprognostic (9.80e-2)" "unprognostic (3.73e-2)" "unprognostic (1.77e-2)" "unprognostic (4.95e-2)" "unprognostic (2.14e-2)" "prognostic unfavorable (4.35e-7)" "unprognostic (1.34e-1)" "unprognostic (2.94e-1)" "unprognostic (1.78e-2)" "unprognostic (2.33e-2)" "unprognostic (6.68e-2)" "unprognostic (8.78e-3)" "unprognostic (2.44e-1)" "unprognostic (2.91e-1)" "unprognostic (8.75e-2)" "unprognostic (4.90e-2)" 14.8 14.5 7.3 24.9 9.7 11.5 11.8 9.3 10.1 13.7 13.0 16.1 14.7 15.0 15.0 18.3 11.7 15.0 13.1 6.8 8.9 13.6 19.7 14.7 21.0 9.5 9.2 12.6 14.9 18.2 10.7 16.7 10.6 15.6 16.8 13.9 13.6 14.1 27.1 11.1 14.4 17.8 8.5 18.6 17.4 26.0 8.5 27.3 18.3 25.6 24.8 16.6 12.3 12.2 48.1 46.9 47.0 48.6 23.9 21.1 69.5 60.7 59.0 55.1 54.3 41.4 64.9 51.3 38.9 65.1 37.2 69.2 65.2 55.2 79.2 83.3 22.4 75.4 46.1 39.5 70.5 76.3 60.6 34.7 46.2 52.5 93.8 36.5 52.2 54.5 68.8 62.9 62.1 69.6 88.3 26.8 53.3 76.8 42.3 86.0 72.7 45.9 37.5 67.1 51.7 34.7 71.7 39.9 51.1 41.9 82.9 47.4 56.3 43.9 27.7 33.4 52.4 37.6 66.2 103.0 53.0 58.9 69.7 16.6 12.9 9.3 7.8 11.7 10.4 7.6 6.9 8.4 11.3 4.0 6.1 8.6 4.4 11.1 9.8 7.3 12.1 9.5 7.3 9.7 9.3 10.1 6.8 8.9 9.5 9.2 10.6 8.5 8.5 12.2 14.2 28.9 31.8 23.2 22.9 10.3 15.2 15.1 15.9 12.7 13.4 9.5 27.1 10.0 25.5 7.3 29.2 24.0 19.8 14.6 13.7 18.0 28.2 24.3 30.0 22.9 13.8 33.0 13.6 24.0 22.7 20.0 17.3 16.8 30.4 26.2 20.7 27.2 24.8 11.8 17.5 17.3 12.2 32.9 8.8 11.2 19.0 31.1 3.6 19.7 41.2 16.9 27.8 18.6 27.9 23.8 14.0 23.0 35.4 29.9 12.5 16.3 34.1 22.7 32.9 19.6 23.2 61.7 41.3 27.2 12.8 25.3 22.8 26.6 18.2 20.2 CREB1 ENSG00000118260 "CAMP responsive element binding protein 1" P16220 2 207529737-207605988 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Differentiation, Host-virus interaction, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 5 "Early spermatids: 417.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003803, HPA019150" Supported Enhanced Nucleoplasm NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "CAB003803: AB_562092, HPA019150: AB_1847220" "unprognostic (1.20e-1)" "unprognostic (3.15e-1)" "unprognostic (3.30e-2)" "unprognostic (2.69e-2)" "unprognostic (3.16e-2)" "unprognostic (1.03e-1)" "prognostic unfavorable (2.77e-5)" "unprognostic (8.41e-2)" "unprognostic (1.04e-2)" "unprognostic (2.53e-1)" "unprognostic (9.58e-2)" "unprognostic (1.74e-2)" "unprognostic (4.82e-3)" "unprognostic (5.53e-3)" "unprognostic (1.06e-1)" "unprognostic (1.77e-1)" "unprognostic (8.45e-2)" 13.0 8.7 10.6 15.3 11.4 22.4 14.7 17.5 11.1 15.8 11.9 11.4 10.0 15.7 10.8 15.0 13.1 14.0 11.5 10.3 10.7 12.4 11.6 13.6 22.1 10.6 9.9 17.2 8.7 15.6 6.9 18.0 10.4 13.0 14.0 17.8 8.9 12.6 6.7 11.5 10.6 16.3 9.7 17.1 12.1 32.4 9.9 28.7 18.1 14.6 25.0 16.8 9.6 15.0 24.9 20.9 38.6 15.6 22.9 22.4 21.8 15.9 23.5 26.6 26.5 21.6 22.9 15.4 19.8 21.1 29.8 19.5 34.8 20.4 37.7 25.1 13.2 29.2 18.9 23.0 18.7 27.7 20.0 16.0 16.3 21.1 31.1 25.4 34.9 28.9 20.5 22.5 30.4 16.8 41.0 16.1 27.8 24.2 13.1 31.4 22.1 20.2 25.1 24.6 27.1 23.4 21.6 16.2 18.1 35.5 16.5 30.1 18.5 21.8 22.6 22.1 20.5 19.6 27.5 36.4 25.2 25.3 22.0 33.6 28.2 28.2 27.0 29.2 23.7 36.7 25.3 26.2 34.1 34.8 30.0 20.7 56.1 45.6 34.9 18.6 38.6 26.7 10.6 11.4 17.5 11.1 10.3 10.7 10.6 9.9 10.4 9.7 9.9 15.0 46.7 19.2 18.2 47.0 52.3 70.9 47.1 33.3 34.1 38.9 25.3 18.5 26.3 17.2 29.0 12.9 33.3 29.1 35.5 25.3 23.5 23.6 417.8 19.6 39.2 47.2 32.4 54.7 56.1 20.3 24.9 35.8 18.8 21.0 43.7 41.5 35.7 15.8 29.4 40.4 51.1 28.2 30.5 48.8 75.9 47.2 26.1 35.8 44.4 68.4 60.9 42.1 33.0 66.9 70.7 26.4 27.5 29.3 29.1 56.5 22.8 19.7 18.9 40.2 39.5 37.4 40.7 44.5 29.4 33.5 57.8 18.6 42.6 19.6 25.7 62.6 CREB3L2 "BBF2H7, TCAG_1951439" ENSG00000182158 "CAMP responsive element binding protein 3 like 2" Q70SY1 7 137874979-138002086 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation, Unfolded protein response" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 141.1;Syncytiotrophoblasts: 144.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015068, HPA015534" Enhanced Supported "Nucleoplasm,Endoplasmic reticulum" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 3: HMC-1 - Innate immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nucleoplasm, Endoplasmic reticulum" "HPA015068: AB_1847224, HPA015534: AB_2669210" "unprognostic (8.50e-2)" "unprognostic (3.70e-2)" "unprognostic (2.77e-1)" "unprognostic (1.50e-3)" "unprognostic (9.88e-2)" "unprognostic (9.09e-2)" "unprognostic (5.17e-2)" "unprognostic (4.50e-1)" "unprognostic (4.77e-1)" "unprognostic (8.93e-2)" "unprognostic (9.48e-2)" "unprognostic (9.65e-2)" "unprognostic (2.42e-1)" "unprognostic (3.08e-3)" "unprognostic (7.65e-2)" "unprognostic (2.59e-2)" "unprognostic (1.32e-2)" 20.7 29.7 8.3 18.5 13.9 23.8 22.8 8.3 12.2 30.3 46.5 22.4 22.3 33.9 26.8 15.0 22.6 15.0 25.9 8.1 9.6 19.6 12.5 19.3 12.8 13.2 10.8 29.0 30.1 59.5 25.1 39.4 12.1 21.6 17.6 5.0 28.7 23.2 6.1 8.7 22.9 29.2 9.6 13.0 17.4 9.0 16.1 10.0 65.3 9.4 20.4 19.5 19.9 17.3 13.1 19.9 37.6 0.6 62.9 61.7 28.1 65.1 104.0 44.4 44.7 27.5 11.7 2.6 16.8 71.1 24.1 6.9 21.9 47.1 86.9 19.1 10.8 83.4 26.7 67.6 41.4 25.3 115.5 25.4 29.2 56.0 65.3 45.5 59.7 6.5 43.8 37.4 52.9 23.5 8.0 31.6 13.6 17.9 13.7 17.5 19.8 22.1 35.3 13.2 9.4 22.3 21.1 54.0 29.1 21.7 7.9 18.9 63.1 59.5 8.7 72.3 24.2 43.9 16.2 16.9 70.9 71.3 135.0 10.4 5.5 6.0 7.3 3.0 9.8 3.9 5.4 8.2 5.7 3.9 2.0 3.4 2.0 7.2 1.6 11.9 12.5 3.2 8.3 13.9 8.3 12.2 8.1 9.6 13.2 10.8 12.1 9.6 16.1 17.3 30.6 6.4 25.9 18.6 27.3 12.2 9.7 18.9 8.0 12.0 32.0 25.4 17.5 21.5 34.9 23.9 10.4 62.6 39.5 24.7 13.7 10.2 56.3 18.1 86.6 31.6 15.7 12.0 7.5 17.6 93.0 49.6 16.3 42.4 49.4 27.8 29.6 24.3 56.3 15.2 10.6 21.0 20.3 34.9 25.6 18.7 61.8 30.7 26.6 63.7 21.4 5.4 40.2 55.8 48.0 14.4 18.2 103.0 141.1 35.1 66.2 7.9 22.4 12.3 39.5 62.3 50.2 3.4 7.4 9.5 7.1 144.5 26.6 11.1 17.0 44.0 CRH "CRF, CRH1" ENSG00000147571 "Corticotropin releasing hormone" P06850 8 66176376-66178464 "Plasma proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "brain: 137.2" "Cell type enriched" "Detected in some" 5 "Syncytiotrophoblasts: 160.6" "Cancer enriched" "Detected in some" 28 "urothelial cancer: 34.5" "Region enriched" "Detected in many" 6 "medulla oblongata: 137.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SuSa: 1.3" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "pons: 25.1" "Secreted to blood" NA NA 10000 "Cluster 73: Brain - Neuropeptide signaling" "Cluster 12: NES - Nervous system development" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "unprognostic (1.62e-1)" "unprognostic (9.68e-2)" "unprognostic (1.00e-1)" "unprognostic (9.55e-2)" "unprognostic (7.22e-3)" 1.5 0.2 5.6 0.0 2.2 0.1 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 9.6 0.0 0.0 0.0 0.0 137.2 9.8 0.0 1.6 0.7 0.2 6.6 16.9 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.8 23.0 0.0 0.1 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 2.2 0.0 5.4 1.3 9.6 137.2 9.8 16.9 0.2 23.0 1.5 0.1 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 20.4 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.0 31.5 0.0 0.0 0.0 0.0 18.8 0.0 0.0 0.0 2.8 0.0 0.0 0.0 1.5 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.4 0.0 0.0 160.6 0.0 0.0 0.0 0.1 CRPPA "hCG_1745121, ISPD, Nip" ENSG00000214960 "CDP-L-ribitol pyrophosphorylase A" A4D126 7 16087525-16502504 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Congenital muscular dystrophy, Disease variant, Dystroglycanopathy, Limb-girdle muscular dystrophy, Lissencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "choroid plexus: 27.0" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 8.0;Cytotrophoblasts: 3.5;Extravillous trophoblasts: 10.6;Syncytiotrophoblasts: 2.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 29 "basophil: 13.8" "Lineage enriched" "Detected in single" 29 "granulocytes: 13.8" "Cell line enhanced" "Detected in many" "HEL: 9.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053554 Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 36: HEL - Hemostasis" "Cluster 24: Non-specific - Transcription regulation" "Nucleoli fibrillar center" Nucleoplasm "HPA053554: AB_2682185" "unprognostic (4.65e-3)" "unprognostic (5.92e-2)" "unprognostic (2.61e-1)" "unprognostic (9.41e-2)" "unprognostic (1.49e-2)" "unprognostic (1.29e-1)" "unprognostic (1.19e-1)" "unprognostic (7.07e-2)" "unprognostic (3.47e-2)" "unprognostic (3.39e-2)" "unprognostic (6.01e-2)" "unprognostic (2.07e-1)" "prognostic favorable (1.38e-11)" "unprognostic (4.01e-2)" "unprognostic (1.78e-4)" "unprognostic (6.26e-2)" "unprognostic (2.79e-1)" 1.1 1.2 1.3 0.8 1.8 1.6 0.9 0.7 3.7 1.3 27.0 1.0 0.6 1.0 0.5 0.5 0.9 1.1 2.6 3.8 1.1 2.9 4.1 1.0 1.4 0.8 0.8 0.7 1.5 1.1 0.7 1.0 0.8 1.0 1.2 1.2 1.2 0.8 1.5 1.2 0.6 1.2 0.2 0.9 3.5 2.2 3.2 1.2 0.8 1.3 1.4 1.1 0.5 2.0 0.4 2.2 1.0 1.6 1.0 1.3 6.8 1.5 1.4 1.5 1.3 2.2 1.9 4.3 3.2 2.7 0.9 2.5 1.2 0.0 2.9 1.5 0.9 9.6 1.4 0.7 1.5 1.9 2.4 2.2 0.8 1.6 0.4 0.9 1.2 3.0 3.2 0.2 4.2 0.7 3.0 1.2 1.8 1.1 0.5 1.1 1.9 0.2 2.1 0.8 1.5 0.9 1.4 2.1 1.7 2.5 1.6 2.0 2.0 1.9 1.5 0.4 1.7 0.4 0.0 4.8 1.5 2.3 2.2 13.8 0.1 0.4 0.2 0.0 0.1 0.2 0.1 0.2 0.0 0.4 0.3 0.2 0.4 0.4 0.1 0.3 0.1 0.0 1.3 1.8 0.7 3.7 3.8 1.1 0.8 0.8 0.8 0.2 3.2 2.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.0 3.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 10.6 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 CRTC3 FLJ21868 ENSG00000140577 "CREB regulated transcription coactivator 3" Q6UUV7 15 90529923-90645345 "Cancer-related genes, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" Activator "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 160.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 21.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HeLa: 83.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043735, HPA063691" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 20: HeLa - Mitochondria" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm Cytosol "HPA043735: AB_10794286, HPA063691: AB_2685092" "unprognostic (7.60e-2)" "unprognostic (6.13e-2)" "unprognostic (1.35e-1)" "unprognostic (2.31e-2)" "unprognostic (5.12e-2)" "unprognostic (3.51e-1)" "unprognostic (1.75e-2)" "unprognostic (1.69e-1)" "unprognostic (6.48e-2)" "unprognostic (3.60e-1)" "unprognostic (1.47e-1)" "unprognostic (2.23e-1)" "unprognostic (5.22e-3)" "unprognostic (4.67e-2)" "unprognostic (9.32e-2)" "unprognostic (9.51e-2)" "unprognostic (2.30e-1)" 27.0 15.5 16.8 14.2 25.3 10.7 21.7 20.0 19.8 26.3 10.1 28.4 7.3 26.0 10.9 12.5 23.8 14.8 19.8 17.0 16.4 14.5 13.2 23.2 15.8 21.8 23.1 36.8 10.7 13.8 9.9 17.1 21.1 18.8 9.4 13.5 17.4 17.0 19.9 19.1 16.6 20.9 16.3 13.3 15.2 16.8 23.2 15.0 22.3 17.4 15.7 28.4 18.3 31.6 9.6 15.1 9.7 16.7 21.6 15.7 46.0 11.7 16.0 17.6 15.9 12.4 9.3 0.2 8.3 23.8 14.9 15.2 15.1 9.8 13.2 16.3 18.8 23.7 83.9 6.1 24.8 6.5 38.8 17.2 16.3 14.5 19.3 13.2 12.5 10.2 12.8 5.5 13.6 11.5 2.6 9.7 3.7 2.7 7.2 8.3 16.3 0.5 6.6 20.3 18.5 16.5 34.7 11.6 19.3 10.8 11.2 12.2 16.4 19.7 14.9 19.0 14.0 7.3 10.2 7.2 8.0 12.6 9.8 21.4 2.6 1.5 3.5 0.8 3.8 2.9 4.3 3.7 1.6 5.0 6.1 3.9 0.5 3.3 0.3 2.1 4.4 3.4 16.8 25.3 20.0 19.8 17.0 16.4 21.8 23.1 21.1 16.3 23.2 31.6 17.9 6.4 9.2 44.1 35.6 23.6 27.8 8.0 13.1 24.9 15.7 12.7 17.0 14.3 7.8 12.9 27.1 14.8 30.0 8.6 1.9 14.9 29.3 6.6 18.5 20.4 15.6 17.1 70.1 10.7 43.3 23.2 14.8 12.7 23.5 34.8 24.7 16.2 15.3 57.2 72.4 9.1 6.1 18.2 18.8 24.3 26.8 21.7 17.8 39.4 20.6 17.7 58.7 75.4 160.8 11.1 10.9 43.6 21.3 26.2 6.4 11.0 2.8 59.7 46.0 30.5 45.8 10.2 17.8 11.4 24.0 17.8 36.0 13.7 11.3 38.2 CRY1 PHLL1 ENSG00000008405 "Cryptochrome circadian regulator 1" Q16526 12 106991364-107093549 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Biological rhythms, Sensory transduction, Transcription, Transcription regulation" "Photoreceptor protein, Receptor, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 108.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB018762 Approved Supported "Nucleoplasm,Nuclear membrane,Microtubules" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Nuclear membrane, Microtubules" "CAB018762: AB_2083970" "unprognostic (1.21e-3)" "unprognostic (4.74e-2)" "unprognostic (6.50e-2)" "unprognostic (9.03e-2)" "unprognostic (1.79e-1)" "unprognostic (2.84e-1)" "unprognostic (3.48e-2)" "unprognostic (3.61e-1)" "unprognostic (4.29e-3)" "unprognostic (1.34e-2)" "unprognostic (6.85e-3)" "unprognostic (2.06e-1)" "unprognostic (1.20e-1)" "unprognostic (1.82e-2)" "unprognostic (5.08e-1)" "unprognostic (1.85e-1)" "unprognostic (2.25e-1)" 13.3 12.4 8.5 7.6 9.8 12.4 11.2 16.2 10.9 11.1 16.7 12.6 11.5 14.2 6.4 11.0 16.4 16.7 11.7 8.4 9.0 13.7 13.6 19.3 5.8 9.8 10.1 9.0 13.5 8.8 8.4 12.1 9.9 11.3 8.6 21.3 9.0 11.5 10.9 9.0 12.7 16.8 9.7 8.7 16.2 37.3 9.9 19.0 17.0 11.0 6.7 15.6 8.6 12.5 17.3 16.9 20.6 23.0 14.6 9.1 36.9 17.9 19.1 36.0 24.2 19.9 10.1 0.0 11.1 16.7 22.7 11.6 26.8 9.3 39.6 17.3 16.6 16.9 15.3 13.8 18.6 17.3 14.2 8.6 9.6 26.4 24.9 17.8 30.5 31.4 19.3 14.6 22.7 12.1 39.2 19.7 25.1 16.5 24.6 34.5 52.3 6.1 25.3 20.2 37.1 19.2 33.6 22.1 10.9 20.0 15.6 9.6 13.5 20.9 22.2 14.6 16.2 26.6 26.6 7.8 10.2 16.3 17.5 12.0 3.2 5.8 12.8 4.7 16.1 1.9 9.6 8.2 4.3 1.9 8.9 8.8 1.4 6.4 8.9 2.8 13.5 5.7 8.5 9.8 16.2 10.9 8.4 9.0 9.8 10.1 9.9 9.7 9.9 12.5 16.3 16.0 16.2 20.5 9.7 69.2 47.9 4.3 55.2 16.8 30.4 14.7 11.1 11.5 6.1 11.0 20.9 8.3 29.1 12.7 17.6 11.4 12.8 27.3 19.3 20.1 19.6 11.2 22.4 16.3 13.4 24.5 45.9 33.2 5.1 6.2 12.1 20.2 6.3 26.9 38.4 9.7 6.1 7.3 21.0 4.8 11.5 8.8 16.0 13.1 16.3 22.8 19.6 35.2 32.8 21.5 7.0 17.3 15.3 29.7 7.7 16.1 18.7 13.7 6.6 24.3 19.2 108.0 32.4 24.3 59.5 15.1 29.7 5.7 6.8 27.0 CRYBG1 "AIM1, ST4" ENSG00000112297 "Crystallin beta-gamma domain containing 1" 6 106360717-106572017 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 61.9;placenta: 72.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 219.4;dendritic cells: 153.6;Plasma cells: 89.9;Syncytiotrophoblasts: 600.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 93.7;HBEC3-KT: 124.1;hTERT-HME1: 95.8" "Region enriched" "Detected in single" 5 "olfactory bulb: 4.2" "Low region specificity" "Detected in many" "CAB026378, HPA030948, HPA030949" Approved Approved Nucleoplasm,Microtubules,Cytosol NA NA "Cluster 13: T-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Microtubules, Cytosol" "CAB026378: , HPA030948: AB_2673670, HPA030949: AB_2673671" "unprognostic (1.66e-1)" "unprognostic (3.44e-2)" "unprognostic (9.02e-3)" "unprognostic (1.13e-1)" "unprognostic (3.80e-1)" "unprognostic (1.52e-1)" "unprognostic (1.40e-1)" "unprognostic (2.27e-2)" "unprognostic (1.08e-1)" "unprognostic (1.23e-1)" "unprognostic (3.69e-3)" "unprognostic (5.61e-2)" "unprognostic (8.97e-2)" "unprognostic (3.53e-2)" "unprognostic (8.89e-2)" "unprognostic (8.60e-2)" "unprognostic (3.25e-2)" 17.0 1.2 0.6 21.9 0.5 24.1 17.3 0.7 0.8 6.8 40.3 25.0 25.4 2.4 6.2 61.9 6.7 8.1 1.0 1.9 0.4 15.3 11.8 9.8 20.4 0.8 0.7 2.3 4.9 5.8 0.4 72.0 0.6 25.2 19.2 0.8 9.3 5.4 1.1 42.1 23.7 4.8 0.5 12.6 10.3 5.1 1.5 9.7 2.6 1.2 33.5 19.0 14.0 0.4 34.7 0.2 0.0 0.1 25.5 93.7 9.9 4.9 33.5 10.8 10.0 2.4 11.5 54.0 2.3 21.7 14.6 54.5 0.2 124.1 5.3 74.0 2.3 0.0 1.5 16.9 12.1 33.4 0.2 44.9 66.7 19.7 95.8 0.1 46.5 41.9 1.7 7.3 28.5 3.5 9.7 10.7 0.4 0.2 21.2 16.4 0.4 0.4 14.9 80.0 2.2 0.2 20.3 31.9 0.3 3.0 16.4 24.3 13.5 11.6 1.5 0.2 34.4 5.7 4.7 57.7 56.0 39.3 26.3 0.3 3.4 0.4 7.4 3.6 10.1 6.6 9.8 8.5 8.6 2.9 5.8 5.7 2.4 4.8 4.1 1.0 9.9 4.0 0.6 0.5 0.7 0.8 1.9 0.4 0.8 0.7 0.6 0.5 1.5 0.4 13.4 12.8 11.9 0.0 24.2 0.0 0.0 0.0 0.0 0.0 31.2 14.1 0.0 0.0 13.0 33.1 0.0 219.4 153.6 0.0 3.9 10.9 0.0 20.2 2.7 4.4 0.0 0.0 0.0 12.5 15.3 2.5 0.0 31.6 1.3 0.1 0.0 0.0 36.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.8 0.0 0.0 5.7 0.0 0.0 0.0 0.0 26.4 0.0 0.0 89.9 0.0 0.0 15.0 8.7 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 600.1 76.7 0.1 0.0 0.0 CSE1L "CAS, CSE1, XPO2" ENSG00000124207 "Chromosome segregation 1 like" P55060 20 49046246-49096960 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 164.0;Spermatogonia: 121.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002140, HPA038059, HPA038060" Enhanced Enhanced Nucleoplasm,Cytosol No Yes 320000 "Cluster 44: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 39: CACO-2 - Unknown function" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "CAB002140: AB_563461, HPA038059: AB_2675811, HPA038060: AB_2675812" "unprognostic (4.01e-2)" "unprognostic (3.15e-2)" "unprognostic (5.63e-2)" "prognostic unfavorable (2.91e-5)" "unprognostic (4.86e-1)" "unprognostic (4.91e-2)" "prognostic unfavorable (2.42e-8)" "unprognostic (3.44e-2)" "unprognostic (1.45e-2)" "unprognostic (2.63e-2)" "unprognostic (2.72e-3)" "unprognostic (2.54e-2)" "prognostic unfavorable (1.89e-4)" "unprognostic (2.59e-1)" "unprognostic (4.84e-1)" "unprognostic (5.71e-1)" "prognostic unfavorable (6.91e-4)" 23.6 24.5 16.0 29.0 20.2 26.4 34.2 26.6 21.1 25.7 12.9 23.6 19.8 28.1 23.8 38.2 27.0 19.0 24.7 17.1 18.0 29.8 30.9 19.7 35.0 21.0 17.3 27.2 20.4 30.8 13.6 37.5 22.8 25.8 28.7 23.2 21.7 25.6 39.8 34.4 19.2 35.0 21.1 20.3 20.7 87.7 17.0 40.7 23.4 41.5 42.8 27.5 22.2 29.1 224.3 152.4 182.1 140.9 69.0 88.5 196.7 172.1 90.5 528.1 222.0 501.8 175.4 227.3 224.1 109.7 213.9 251.4 270.7 322.9 500.0 37.4 131.3 158.0 166.1 244.7 42.0 176.2 83.3 50.0 118.7 259.0 148.7 72.4 177.5 124.3 227.2 87.1 201.1 76.8 213.9 90.6 153.5 185.1 224.0 133.9 299.5 176.4 116.5 153.2 159.6 92.6 275.2 293.3 97.1 137.7 245.3 113.3 115.5 279.3 233.9 166.4 247.9 50.5 130.8 210.8 166.8 139.5 152.2 18.6 16.3 3.8 13.8 20.6 21.1 16.7 21.0 17.1 20.1 13.6 22.1 19.3 4.4 23.0 23.6 8.9 20.1 18.3 16.0 20.2 26.6 21.1 17.1 18.0 21.0 17.3 22.8 21.1 17.0 29.1 16.4 6.4 26.8 8.1 20.3 30.2 25.8 29.5 31.3 14.9 17.4 15.9 26.6 24.3 22.4 27.6 10.4 71.8 15.7 7.4 13.7 32.2 95.9 14.7 19.4 22.9 5.4 40.4 20.9 26.6 61.2 24.6 13.7 17.8 4.5 35.1 19.2 26.7 29.7 15.2 24.4 11.8 20.3 17.9 21.9 57.8 25.4 17.9 26.6 9.4 28.0 22.6 7.2 17.1 41.7 26.7 10.0 31.6 26.7 28.8 9.9 21.6 21.7 15.5 39.5 19.3 22.1 164.0 121.5 36.7 34.5 72.7 17.5 31.1 23.7 22.2 CSF2RB "betaGMR, CD131, IL3RB, IL5RB" ENSG00000100368 "Colony stimulating factor 2 receptor subunit beta" P32927 22 36913628-36940439 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 54.5;lymphoid tissue: 65.5" "Cell type enhanced" "Detected in many" "dendritic cells: 44.8;Extravillous trophoblasts: 37.9;granulocytes: 91.2;Langerhans cells: 68.3;Late spermatids: 41.2;Macrophages: 34.7;monocytes: 42.3;Plasma cells: 49.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 7 "basophil: 238.1;neutrophil: 76.0" "Lineage enriched" "Detected in many" 16 "granulocytes: 238.1" "Group enriched" "Detected in some" 5 "HEL: 107.3;HMC-1: 321.1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA078677 Approved "Golgi apparatus" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Golgi apparatus" "HPA078677: AB_2732389" "unprognostic (1.67e-2)" "unprognostic (9.44e-3)" "unprognostic (1.03e-2)" "unprognostic (6.66e-3)" "unprognostic (1.51e-1)" "prognostic favorable (7.47e-5)" "unprognostic (1.86e-1)" "unprognostic (1.94e-2)" "unprognostic (4.38e-1)" "unprognostic (9.57e-2)" "unprognostic (1.33e-1)" "unprognostic (3.21e-1)" "unprognostic (1.82e-3)" "unprognostic (5.76e-2)" "unprognostic (3.65e-2)" "unprognostic (1.95e-1)" "unprognostic (8.52e-2)" 10.1 2.0 1.0 65.5 1.1 54.5 5.4 1.2 5.2 2.5 1.3 9.9 10.3 2.0 0.7 6.6 2.6 9.8 2.3 0.9 1.6 1.8 2.6 15.1 40.1 2.6 2.1 0.5 2.1 0.9 0.7 31.3 3.1 1.6 8.5 0.0 4.9 1.5 1.0 5.4 11.0 7.0 2.3 22.8 9.3 2.1 3.0 9.8 2.7 4.0 62.5 18.3 2.5 2.9 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.1 0.0 0.0 0.0 0.0 0.0 26.8 0.1 0.0 0.0 0.3 0.0 0.0 0.1 16.1 0.0 107.3 0.0 0.0 0.1 1.7 321.1 0.0 0.0 0.0 0.0 0.0 18.5 0.0 0.1 12.6 0.0 0.0 0.1 11.2 0.0 0.0 0.0 10.7 0.0 40.0 0.0 0.0 0.1 0.0 0.0 2.5 0.0 0.1 0.1 9.6 0.3 1.0 0.1 0.3 0.0 1.6 1.1 6.8 0.2 15.6 0.1 238.1 9.1 23.5 0.0 7.7 0.0 1.6 0.2 0.0 4.8 1.1 0.0 0.0 76.0 0.0 7.0 14.4 2.3 10.3 1.0 1.1 1.2 5.2 0.9 1.6 2.6 2.1 3.1 2.3 3.0 2.9 4.3 0.0 9.1 1.6 9.1 7.1 0.0 0.0 0.0 0.0 0.2 0.3 1.2 2.8 1.8 0.0 0.0 3.4 44.8 0.0 0.0 0.0 13.4 0.0 0.2 22.0 0.0 32.0 0.1 0.2 37.9 2.8 0.0 0.0 91.2 0.0 4.6 0.0 20.1 0.0 0.1 0.0 0.0 31.9 68.3 41.2 0.0 34.7 12.4 5.6 42.3 0.0 2.1 0.0 0.0 0.0 0.0 0.4 49.5 0.1 0.0 0.1 2.9 0.0 0.0 0.3 0.5 0.0 0.0 0.1 6.3 16.6 2.9 0.1 0.0 0.2 CSMD3 ENSG00000164796 "CUB and Sushi multiple domains 3" Q7Z407 8 112222928-113436939 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "brain: 6.8" "Group enriched" "Detected in some" 12 "Excitatory neurons: 915.9;Inhibitory neurons: 867.9;Oligodendrocyte precursor cells: 1761.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029007, HPA029008" Uncertain Approved "Plasma membrane" NA NA "Cluster 65: Brain - Ion transport" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA029007: AB_10601802, HPA029008: " "unprognostic (2.26e-1)" "unprognostic (2.16e-2)" "unprognostic (2.83e-2)" "unprognostic (5.97e-2)" "unprognostic (3.44e-2)" "unprognostic (1.26e-2)" "unprognostic (3.54e-4)" "unprognostic (2.48e-1)" "unprognostic (2.54e-1)" "unprognostic (2.89e-2)" "unprognostic (2.33e-2)" "unprognostic (5.03e-10)" "unprognostic (1.95e-1)" "unprognostic (4.14e-3)" "unprognostic (1.91e-2)" "unprognostic (1.74e-3)" 0.0 0.0 6.8 0.0 4.3 0.0 0.0 0.0 6.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 5.7 4.8 0.0 0.0 0.0 0.0 1.9 2.7 0.0 0.2 0.0 0.1 0.0 1.6 0.2 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.9 5.0 0.0 0.0 0.0 0.0 0.0 0.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 4.3 0.0 6.0 5.7 4.8 1.9 2.7 1.6 0.8 5.0 0.7 0.0 0.0 3.0 21.5 0.2 0.3 0.1 0.0 0.0 7.3 0.0 0.0 1.6 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.8 0.5 0.1 0.4 0.0 0.0 915.9 0.0 0.0 0.9 0.0 0.2 0.0 4.6 0.0 0.0 0.0 0.0 867.9 0.0 0.0 0.0 0.8 6.3 0.0 0.3 0.0 19.7 0.0 0.5 0.0 1761.3 92.2 0.1 0.0 0.0 0.0 0.3 0.0 0.1 0.2 0.9 0.0 0.4 0.2 17.1 8.2 0.0 0.6 0.0 0.0 0.0 0.0 0.3 CSNK1G2 CK1g2 ENSG00000133275 "Casein kinase 1 gamma 2" P78368 19 1941172-1981338 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 254.8;Late spermatids: 613.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034868, HPA056572" Uncertain Approved Vesicles NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "HPA034868: AB_10671235, HPA056572: AB_2683178" "unprognostic (2.00e-1)" "unprognostic (2.15e-1)" "unprognostic (1.83e-1)" "unprognostic (2.42e-3)" "unprognostic (6.51e-3)" "unprognostic (2.27e-3)" "unprognostic (1.14e-3)" "unprognostic (2.00e-1)" "unprognostic (9.42e-2)" "unprognostic (5.78e-2)" "unprognostic (4.83e-3)" "unprognostic (4.09e-3)" "unprognostic (7.95e-2)" "unprognostic (4.65e-3)" "unprognostic (5.09e-1)" "unprognostic (2.01e-1)" "unprognostic (1.63e-2)" 37.1 52.7 19.3 40.5 17.9 47.3 38.3 22.8 28.1 35.1 18.3 35.0 29.5 34.5 6.5 50.6 35.7 20.6 33.8 21.6 16.6 42.6 41.6 53.5 41.8 20.8 19.2 39.5 39.8 13.3 51.5 17.7 18.1 41.3 8.7 9.8 38.1 14.0 39.4 45.1 46.9 10.3 12.8 69.2 35.5 99.9 18.3 23.5 35.8 12.3 18.7 32.3 37.8 18.1 71.2 37.3 51.0 80.1 17.5 32.6 42.7 43.1 28.0 32.0 39.1 31.0 37.8 44.3 35.2 27.6 17.8 50.1 27.6 52.5 14.0 40.5 60.4 31.2 65.0 52.9 28.2 50.7 76.3 32.5 33.8 33.4 21.3 24.7 38.4 54.2 67.1 146.5 21.4 41.3 101.0 66.8 92.7 19.7 41.8 86.8 32.3 72.7 24.3 73.2 81.9 67.4 32.2 52.7 48.2 18.8 33.6 81.8 46.6 40.2 31.5 85.3 50.6 94.8 54.5 55.5 40.7 47.6 42.8 2.8 3.6 4.7 4.2 5.8 3.0 3.4 3.1 3.6 3.6 3.3 2.4 3.4 10.0 3.5 14.4 5.4 2.4 2.4 19.3 17.9 22.8 28.1 21.6 16.6 20.8 19.2 18.1 12.8 18.3 18.1 37.5 16.0 17.9 10.1 36.5 21.9 17.8 14.9 10.8 43.6 28.9 26.8 14.2 10.0 14.9 11.0 41.7 12.2 91.7 36.9 9.8 17.1 254.8 37.7 32.5 24.7 30.5 12.6 10.8 29.5 18.9 21.6 31.1 32.4 29.9 41.8 16.8 16.4 14.9 25.2 9.8 26.6 6.1 21.9 30.3 613.6 20.5 32.3 14.2 14.0 16.4 21.6 41.2 5.5 6.2 30.1 24.0 18.8 38.2 28.8 15.0 14.6 22.8 39.3 13.1 26.4 23.0 16.0 13.2 19.0 25.3 18.2 46.2 51.7 24.8 32.8 CSPG4 "CSPG4A, HMW-MAA, MCSP, MCSPG, MEL-CSPG, MSK16, NG2" ENSG00000173546 "Chondroitin sulfate proteoglycan 4" Q6UVK1 15 75674322-75712848 "Predicted membrane proteins" "Angiogenesis, Differentiation, Tissue remodeling" "Developmental protein, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 55.4" "Group enriched" "Detected in some" 5 "Oligodendrocyte precursor cells: 57.3;Sertoli cells: 118.3;Smooth muscle cells: 47.1" "Cancer enhanced" "Detected in all" "melanoma: 74.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 64.7;SK-MEL-30: 146.1;U-138 MG: 92.1;WM-115: 138.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001933, HPA002951, CAB016189, HPA042785, HPA050008" Approved Enhanced "Nucleoplasm,Plasma membrane" NA NA 48000000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" Nucleoplasm "CAB016189: AB_784821, HPA001933: , HPA002951: AB_1854449, HPA042785: AB_10964270, HPA050008: AB_2680991" "unprognostic (5.21e-2)" "unprognostic (2.17e-3)" "unprognostic (3.55e-2)" "unprognostic (1.01e-2)" "unprognostic (3.56e-2)" "unprognostic (3.58e-1)" "unprognostic (1.09e-2)" "unprognostic (2.11e-2)" "unprognostic (1.07e-1)" "unprognostic (5.00e-2)" "unprognostic (1.63e-1)" "unprognostic (3.14e-1)" "prognostic unfavorable (7.60e-6)" "unprognostic (1.23e-2)" "unprognostic (2.04e-2)" "unprognostic (3.21e-2)" "prognostic unfavorable (4.93e-5)" 29.6 1.8 9.0 7.3 7.1 0.0 18.5 6.6 9.3 16.0 1.8 55.4 2.8 34.5 1.4 8.3 15.0 5.6 14.6 7.5 8.2 4.9 0.9 19.4 0.4 11.7 7.8 8.9 2.1 1.2 2.2 15.5 9.7 14.4 2.2 0.1 4.7 11.2 39.6 7.8 15.3 22.7 6.7 5.6 19.1 1.3 7.7 0.6 5.6 10.0 0.3 30.3 12.6 9.8 11.9 0.1 1.0 7.1 1.6 9.8 0.1 64.7 28.6 44.4 28.8 0.1 45.0 0.0 1.5 45.4 6.2 0.6 0.1 0.3 13.6 0.6 0.2 0.0 19.2 0.0 10.0 0.0 0.1 4.8 0.1 13.5 1.5 16.5 0.0 0.0 0.1 0.1 7.6 0.1 0.0 0.2 1.2 0.0 0.3 0.1 4.0 0.1 0.0 0.0 0.1 0.2 1.7 0.1 146.1 1.2 0.9 1.2 0.1 92.1 17.9 3.6 0.8 0.0 0.2 0.0 20.3 0.5 138.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 9.0 7.1 6.6 9.3 7.5 8.2 11.7 7.8 9.7 6.7 7.7 9.8 4.9 0.0 0.0 1.0 0.0 2.8 0.7 4.7 0.0 1.4 0.1 0.8 11.4 0.0 0.8 1.8 0.0 0.2 0.5 0.1 0.0 0.0 0.6 0.7 0.7 2.7 0.0 0.0 0.4 0.0 0.6 5.9 1.5 0.4 0.0 1.8 1.1 0.2 1.1 0.0 0.2 0.0 0.0 0.0 3.2 0.0 0.3 0.3 12.4 3.7 0.0 0.0 0.0 57.3 0.1 0.0 0.0 0.4 0.0 4.3 0.0 0.1 1.0 0.2 118.3 3.1 47.1 0.0 1.3 0.1 1.8 0.3 0.3 0.1 0.0 0.4 CSRP2 "CRP2, LMO5, SmLIM" ENSG00000175183 "Cysteine and glycine rich protein 2" Q16527 12 76858709-76879023 "Predicted intracellular proteins" Differentiation "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 275.3;Muller glia cells: 625.9;Smooth muscle cells: 268.4;Squamous epithelial cells: 271.2" "Cancer enhanced" "Detected in all" "glioma: 24.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 336.2;BEWO: 177.9;fHDF/TERT166: 184.9;HEK 293: 186.4;NTERA-2: 181.4;WM-115: 188.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045617 Uncertain NA NA 63000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" "HPA045617: AB_2679391" "unprognostic (9.06e-2)" "unprognostic (4.32e-2)" "unprognostic (5.18e-3)" "unprognostic (1.58e-1)" "unprognostic (5.40e-1)" "unprognostic (2.79e-3)" "unprognostic (2.09e-1)" "unprognostic (1.01e-1)" "unprognostic (1.18e-1)" "unprognostic (3.54e-2)" "unprognostic (2.67e-1)" "prognostic favorable (8.52e-4)" "prognostic unfavorable (4.48e-5)" "unprognostic (3.55e-2)" "unprognostic (4.41e-1)" "unprognostic (3.08e-1)" "unprognostic (3.45e-1)" 68.9 8.2 52.7 32.6 55.5 0.3 52.2 56.9 70.0 77.4 54.4 34.2 17.2 54.3 27.1 98.0 55.8 61.6 37.4 51.6 62.6 88.3 45.2 57.7 27.8 55.5 56.6 30.1 16.6 11.6 28.7 84.0 57.7 48.5 16.3 64.9 29.9 15.9 15.3 24.1 39.0 37.2 55.5 19.4 45.8 23.7 61.4 26.9 50.0 34.4 37.5 47.4 62.6 61.4 26.0 23.0 336.2 67.7 15.0 3.3 177.9 43.7 52.5 39.3 108.2 15.3 1.1 0.3 17.5 184.9 30.9 31.4 75.3 44.5 63.0 3.2 186.4 0.3 46.4 14.9 3.7 0.0 0.7 18.0 29.5 31.8 5.6 67.8 8.1 12.9 1.2 1.0 68.8 8.3 3.8 0.3 181.4 1.6 39.1 39.5 90.9 0.3 130.3 61.7 17.4 111.8 74.3 2.7 17.9 92.5 0.1 0.8 1.9 34.3 44.4 8.5 32.6 2.2 1.9 3.7 10.5 0.6 188.5 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 52.7 55.5 56.9 70.0 51.6 62.6 55.5 56.6 57.7 55.5 61.4 61.4 93.8 0.0 1.7 6.2 1.8 78.5 105.5 24.3 133.7 16.7 12.7 57.0 14.4 20.0 8.5 14.7 10.4 275.3 2.7 0.8 215.2 28.5 35.3 107.1 16.1 119.1 0.0 0.0 4.7 4.4 156.7 116.6 7.7 82.4 0.0 61.7 13.2 25.7 28.8 0.0 2.1 2.5 2.0 1.0 43.7 21.0 3.7 5.3 49.8 13.1 76.1 625.9 0.0 2.5 0.6 5.5 1.4 9.1 8.1 72.7 0.4 140.8 2.7 19.4 210.4 138.0 268.4 81.2 44.8 271.2 61.9 117.9 5.9 25.1 3.8 55.0 CST3 ENSG00000101439 "Cystatin C" P01034 20 23626706-23638473 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Age-related macular degeneration, Amyloidosis, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 4217.6" "Cell type enriched" "Detected in all" 4 "Langerhans cells: 18746.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "classical monocyte: 4967.5;intermediate monocyte: 6424.5;myeloid DC: 7959.0;non-classical monocyte: 4297.7;plasmacytoid DC: 4427.4" "Group enriched" "Detected in all" 9 "dendritic cells: 7959.0;monocytes: 6424.5" "Cell line enhanced" "Detected in many" "ASC diff: 1733.4;ASC TERT1: 1179.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000118, HPA013143" Enhanced Supported "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 1040000000 2800000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 41: Macrophages - Immune response" "Golgi apparatus, Vesicles" "CAB000118: , HPA013143: AB_1847417" "unprognostic (3.89e-2)" "unprognostic (1.63e-1)" "unprognostic (1.45e-1)" "prognostic favorable (1.83e-4)" "unprognostic (8.53e-2)" "unprognostic (4.06e-2)" "unprognostic (2.10e-2)" "unprognostic (2.18e-2)" "unprognostic (3.46e-2)" "unprognostic (3.72e-1)" "unprognostic (2.29e-3)" "unprognostic (3.51e-2)" "unprognostic (1.85e-1)" "unprognostic (1.16e-1)" "unprognostic (2.97e-1)" "unprognostic (5.01e-2)" "prognostic favorable (8.77e-4)" 1046.2 707.6 3041.2 262.3 3117.9 170.8 900.3 2823.3 4217.6 587.8 3094.8 788.7 389.6 708.3 875.9 557.1 802.7 583.0 1275.3 2976.3 2707.6 517.4 833.6 595.8 463.5 3258.4 3096.2 575.8 944.1 320.0 670.1 165.9 2939.3 773.9 416.9 46.9 2008.0 441.5 749.0 497.1 800.3 367.6 3028.1 723.7 979.9 761.3 3302.7 418.9 658.8 517.4 208.1 703.0 618.4 2883.1 155.2 328.2 75.4 175.8 1733.4 1179.8 145.3 261.4 350.7 170.3 137.7 625.1 219.7 0.8 241.0 345.2 221.3 496.2 69.6 499.9 51.9 0.9 253.5 157.6 61.1 1082.9 621.2 7.5 251.0 919.0 415.9 226.6 241.5 352.5 268.5 18.5 147.6 4.0 239.5 234.4 1.5 162.2 103.5 461.9 752.2 5.7 96.4 215.2 708.0 328.3 84.7 98.2 191.1 54.6 343.3 107.7 156.5 548.2 702.0 163.4 119.0 231.6 97.7 157.1 6.2 1.8 138.0 339.5 184.0 48.1 4967.5 33.2 66.9 6424.5 25.5 23.1 18.3 45.8 7959.0 13.6 16.9 31.1 809.3 191.4 4297.7 4427.4 13.6 4250.8 3041.2 3117.9 2823.3 4217.6 2976.3 2707.6 3258.4 3096.2 2939.3 3028.1 3302.7 2883.1 662.4 115.4 168.8 849.5 93.8 942.9 571.1 568.2 213.9 152.4 660.2 512.1 240.7 1361.2 514.5 641.9 29.2 476.8 603.3 1889.9 414.8 489.9 46.2 441.1 795.0 728.2 882.1 252.1 4.5 783.6 308.7 3026.2 981.7 631.0 359.9 687.0 491.9 2563.0 1816.7 48.8 11.2 1360.6 691.7 4301.1 18746.6 184.3 2132.6 4542.6 1563.5 87.1 2025.6 248.7 99.9 263.9 6.0 1458.5 2342.1 1790.4 67.9 786.0 4301.1 1098.6 364.4 36.3 2195.7 1417.0 846.2 125.5 400.6 461.5 822.0 469.0 117.4 208.1 1039.4 1079.7 CST8 "CRES, CTES5" ENSG00000125815 "Cystatin 8" O60676 20 23491101-23496010 "Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 203 "testis: 22.3" "Group enriched" "Detected in some" 128 "Early spermatids: 188.7;Late spermatids: 119.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 29: Early spermatids - Spermatogenesis" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 188.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 119.6 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CSTL1 "CTES1, dJ322G13.4" ENSG00000125823 "Cystatin like 1" Q9H114 20 23439685-23444930 "Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 18 "testis: 4.4" "Group enriched" "Detected in some" 631 "Early spermatids: 51.3;Late spermatids: 74.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (1.14e-1)" "unprognostic (1.54e-1)" "unprognostic (3.25e-3)" "unprognostic (2.04e-1)" "unprognostic (6.58e-2)" "unprognostic (2.68e-1)" "unprognostic (1.61e-1)" "unprognostic (5.40e-2)" "unprognostic (3.63e-1)" "unprognostic (2.97e-1)" "unprognostic (6.87e-2)" "unprognostic (2.35e-1)" "unprognostic (5.36e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 51.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 74.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 CTSS ENSG00000163131 "Cathepsin S" P25774 1 150730079-150765957 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 137.0;lymphoid tissue: 164.8" "Cell type enhanced" "Detected in many" "Hofbauer cells: 698.6;Kupffer cells: 2230.8;Macrophages: 1316.2;monocytes: 2312.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 2483.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 81.6;HMC-1: 187.5;U-698: 387.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000460, HPA002988" Supported Approved Vesicles "Intracellular and membrane" NA NA 23000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "CAB000460: , HPA002988: AB_1078409" "unprognostic (7.81e-2)" "unprognostic (9.04e-2)" "unprognostic (3.23e-2)" "unprognostic (3.93e-2)" "unprognostic (1.52e-1)" "unprognostic (1.12e-2)" "unprognostic (1.11e-1)" "unprognostic (1.23e-1)" "unprognostic (1.59e-1)" "unprognostic (6.00e-3)" "unprognostic (1.46e-1)" "unprognostic (3.89e-1)" "unprognostic (6.24e-2)" "unprognostic (7.50e-2)" "unprognostic (4.14e-2)" "unprognostic (2.13e-1)" "unprognostic (2.47e-3)" 40.0 16.7 4.0 87.8 4.5 137.0 20.3 4.8 7.1 9.4 8.0 83.6 60.2 7.8 5.7 16.5 17.8 29.1 10.6 3.4 5.5 9.3 40.4 88.4 71.7 11.8 8.0 4.9 11.3 2.3 4.7 23.6 11.2 9.1 59.4 3.4 23.9 7.3 4.1 7.1 64.6 16.3 7.7 164.8 42.6 3.8 10.4 20.1 11.5 9.0 38.5 42.9 10.0 16.1 3.7 10.9 0.2 0.3 1.2 1.4 0.7 0.4 8.6 0.9 1.3 1.2 81.6 44.3 5.7 1.2 15.3 2.1 0.2 0.7 0.5 26.9 0.2 29.0 1.1 0.8 0.2 33.6 187.5 2.6 0.1 6.6 1.5 0.5 6.3 0.6 3.4 45.0 2.4 0.3 0.4 22.5 0.2 0.1 0.3 14.9 4.6 49.8 10.7 8.7 0.3 0.4 1.1 2.3 0.8 0.3 0.4 49.8 9.1 6.2 1.3 0.8 1.2 27.8 2.2 387.3 28.5 35.2 2.3 20.9 2483.4 218.0 41.3 1735.3 51.1 139.5 46.6 50.9 571.0 138.8 45.0 40.8 1022.2 41.8 1655.1 106.8 77.4 2577.6 4.0 4.5 4.8 7.1 3.4 5.5 11.8 8.0 11.2 7.7 10.4 16.1 37.6 109.0 158.7 1.6 255.3 17.0 31.3 72.0 4.6 2.3 21.0 8.9 5.3 74.4 143.4 42.3 12.5 3.7 198.0 549.2 0.0 183.6 6.6 126.9 8.6 44.1 42.4 22.5 10.3 177.0 5.7 34.4 71.9 39.0 106.8 9.5 60.3 30.6 698.6 0.0 9.5 205.7 73.2 2230.8 316.4 3.0 5.3 1316.2 56.9 27.2 2312.9 0.5 137.0 0.5 0.9 200.9 466.5 2.2 121.4 20.6 210.8 4.7 488.9 4.9 19.7 5.6 13.3 0.2 0.5 12.4 15.5 6.2 108.9 66.0 237.8 113.3 CTSV "CTSL2, CTSU" ENSG00000136943 "Cathepsin V" O60911 9 97029677-97156556 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "lymphoid tissue: 643.6" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 63.7;Cytotrophoblasts: 122.3;Extravillous trophoblasts: 153.0;Granulosa cells: 54.2;Syncytiotrophoblasts: 67.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in some" 4 "plasmacytoid DC: 15.1" "Lineage enriched" "Detected in many" 4 "dendritic cells: 15.1" "Group enriched" "Detected in many" 8 "BEWO: 592.6;SuSa: 739.0" "Low region specificity" "Detected in all" CAB017112 Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 370000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoli fibrillar center, Cytosol" "Nucleoplasm, Plasma membrane" "CAB017112: " "unprognostic (2.40e-1)" "unprognostic (2.74e-2)" "unprognostic (1.50e-1)" "prognostic favorable (8.41e-4)" "unprognostic (7.29e-2)" "unprognostic (5.59e-2)" "prognostic unfavorable (2.83e-5)" "unprognostic (7.04e-3)" "unprognostic (6.06e-2)" "unprognostic (1.39e-2)" "prognostic unfavorable (2.87e-4)" "unprognostic (1.86e-2)" "unprognostic (1.78e-1)" "unprognostic (2.41e-2)" "unprognostic (1.33e-1)" "unprognostic (3.04e-3)" "prognostic unfavorable (2.39e-4)" 0.2 0.2 0.6 0.3 0.7 0.3 5.8 0.8 1.6 43.1 0.8 2.9 1.1 2.8 1.7 19.8 1.3 0.5 0.1 0.6 0.5 21.3 0.2 0.9 0.1 0.7 0.6 0.2 2.1 1.4 1.5 16.8 0.6 0.7 3.2 17.2 9.4 0.1 0.7 52.5 0.4 0.8 0.5 0.2 2.8 65.8 0.6 643.6 1.3 0.1 6.0 0.4 20.1 1.0 37.1 5.2 12.1 33.1 0.6 0.0 592.6 0.5 0.0 7.1 4.7 81.0 37.7 0.3 2.8 0.5 50.5 67.2 58.8 43.9 9.7 0.1 4.4 0.8 1.9 3.1 0.2 0.1 3.3 0.0 9.2 1.5 0.8 0.9 2.4 8.5 0.5 0.2 14.4 15.2 0.9 0.3 76.2 78.9 10.7 0.0 27.3 0.1 11.4 3.7 2.4 3.6 39.1 13.1 13.2 739.0 21.1 3.2 0.0 1.0 23.6 0.2 3.5 5.7 20.6 0.8 1.6 0.4 4.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.1 0.0 0.2 3.3 0.0 15.1 0.0 0.1 0.6 0.7 0.8 1.6 0.6 0.5 0.7 0.6 0.6 0.5 0.6 1.0 0.9 0.0 1.1 0.3 0.9 30.3 13.0 63.7 19.9 4.6 13.1 9.9 1.3 0.0 17.4 1.8 10.4 122.3 6.9 4.7 1.9 1.8 2.6 15.0 2.9 1.8 1.8 0.0 0.6 0.8 153.0 3.2 0.0 24.0 0.0 54.2 0.4 0.0 13.6 0.0 0.9 1.5 10.2 0.8 3.0 8.2 4.1 2.4 0.0 0.0 0.2 6.5 0.0 0.0 3.5 0.5 10.5 1.2 0.0 8.1 0.1 22.1 4.2 36.6 6.6 1.4 3.6 46.7 33.7 8.2 11.9 67.3 0.5 0.7 4.2 8.4 CTTNBP2 "C7orf8, CORTBP2, KIAA1758, Orf4" ENSG00000077063 "Cortactin binding protein 2" Q8WZ74 7 117710651-117874139 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.1" "Cell type enhanced" "Detected in many" "Excitatory neurons: 128.8;granulocytes: 139.9;Inhibitory neurons: 194.9;Oligodendrocyte precursor cells: 428.8;Oligodendrocytes: 444.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "non-classical monocyte: 7.7" "Lineage enriched" "Detected in single" 26 "monocytes: 7.7" "Group enriched" "Detected in some" 6 "HEL: 57.6;HMC-1: 74.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009151, HPA044654" Enhanced Approved "Midbody ring,Cytosol" Yes No "Cluster 14: Monocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 3: HMC-1 - Innate immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Midbody ring, Cytosol" "CAB009151: AB_2088281, HPA044654: AB_2679037" "unprognostic (6.28e-2)" "unprognostic (2.90e-1)" "unprognostic (5.11e-2)" "unprognostic (1.81e-3)" "unprognostic (1.21e-1)" "unprognostic (3.64e-1)" "unprognostic (7.38e-2)" "unprognostic (3.28e-4)" "unprognostic (3.83e-1)" "unprognostic (7.98e-2)" "unprognostic (7.93e-3)" "unprognostic (1.20e-1)" "prognostic favorable (3.71e-5)" "unprognostic (1.10e-1)" "unprognostic (1.27e-1)" "unprognostic (6.06e-2)" "unprognostic (2.45e-3)" 6.9 1.8 11.4 0.7 16.7 0.0 3.8 13.0 14.7 5.7 6.8 2.4 1.6 10.6 4.8 12.1 6.0 3.5 1.8 12.7 14.8 6.4 1.8 1.8 0.2 15.7 14.7 3.1 7.8 9.3 2.9 1.7 16.3 3.4 2.4 7.9 3.4 1.8 0.5 1.8 2.4 5.2 11.9 2.2 1.3 1.0 15.1 0.7 5.5 0.9 0.9 4.2 4.2 26.1 0.0 0.9 1.6 0.0 0.0 0.0 1.2 0.2 0.6 0.0 0.0 0.0 0.0 0.0 9.2 0.0 0.0 0.1 8.3 0.0 0.0 0.0 2.5 57.6 0.5 0.0 0.2 0.0 74.1 0.3 0.4 0.0 0.0 1.0 1.6 0.0 0.0 0.1 1.1 0.0 0.0 0.0 10.6 0.0 0.3 0.0 0.0 0.2 10.6 0.0 6.1 0.0 0.0 0.0 0.2 4.6 0.0 0.0 0.0 2.6 1.0 0.1 0.0 0.7 0.0 0.2 5.0 0.0 1.3 0.0 0.3 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 11.4 16.7 13.0 14.7 12.7 14.8 15.7 14.7 16.3 11.9 15.1 26.1 15.6 3.2 4.8 10.1 0.0 1.9 3.4 3.7 15.9 33.6 1.9 6.7 3.6 10.0 5.6 7.3 56.3 2.8 0.3 1.8 1.9 6.3 1.8 5.1 32.5 10.2 1.8 0.0 128.8 4.2 2.1 9.1 1.1 7.4 139.9 3.8 20.0 1.1 9.2 74.0 194.9 1.1 24.4 10.1 12.3 3.3 0.9 8.0 7.2 75.9 1.3 97.2 0.0 428.8 444.2 0.6 2.1 1.2 0.3 2.1 0.3 24.3 1.4 6.6 0.0 3.3 9.6 0.6 2.1 38.8 0.3 1.1 2.7 0.2 6.8 1.4 CUBN "gp280, IFCR, MGA1" ENSG00000107611 Cubilin O60494 10 16823966-17129811 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Cholesterol metabolism, Endocytosis, Lipid metabolism, Protein transport, Steroid metabolism, Sterol metabolism, Transport" Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "kidney: 140.4" "Group enriched" "Detected in many" 7 "Proximal enterocytes: 257.7;Proximal tubular cells: 325.0" "Cancer enriched" "Detected in some" 15 "renal cancer: 24.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 14.8;ASC TERT1: 3.0;SK-MEL-30: 2.8;WM-115: 5.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA004133, HPA043854" Enhanced "Intracellular and membrane" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA004133: AB_2732398, HPA043854: AB_2732510" "unprognostic (1.75e-1)" "unprognostic (2.35e-1)" "unprognostic (2.12e-3)" "unprognostic (8.61e-4)" "unprognostic (9.54e-2)" "unprognostic (2.78e-2)" "unprognostic (2.88e-2)" "unprognostic (7.03e-2)" "unprognostic (1.24e-1)" "unprognostic (7.16e-2)" "unprognostic (1.98e-2)" "unprognostic (2.47e-1)" "prognostic favorable (1.12e-4)" "unprognostic (6.24e-3)" "unprognostic (1.97e-1)" "unprognostic (2.00e-1)" "unprognostic (1.93e-1)" 0.7 0.8 0.8 0.4 0.9 0.4 0.8 0.8 0.7 1.2 1.3 0.5 0.2 0.7 3.1 0.2 2.1 0.3 0.6 0.8 0.8 140.4 0.1 0.6 0.8 2.5 1.7 2.5 0.5 0.6 2.2 2.6 2.4 1.1 0.2 3.0 0.7 0.4 0.3 0.8 28.0 0.4 1.7 0.9 0.4 2.0 1.0 1.7 3.8 0.5 0.7 0.4 0.7 0.6 0.0 0.0 1.5 14.8 0.5 3.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.8 1.0 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.5 0.0 0.6 1.5 0.6 0.1 0.2 0.2 0.0 0.2 0.1 0.2 0.0 0.1 0.0 0.2 0.0 0.4 0.0 0.0 0.3 0.0 0.0 2.8 0.1 0.0 0.1 1.6 0.1 0.2 0.3 0.1 0.5 0.0 0.0 0.4 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.9 0.8 0.7 0.8 0.8 2.5 1.7 2.4 1.7 1.0 0.6 3.2 0.0 1.5 23.8 3.7 0.5 0.4 0.2 0.6 2.9 0.6 0.6 1.7 0.0 3.2 5.5 2.1 0.0 3.3 0.1 13.7 0.0 37.3 3.1 2.2 5.7 0.0 0.0 8.4 0.2 0.0 2.3 0.0 2.2 0.0 2.2 1.4 0.0 0.1 0.0 9.0 3.7 0.0 0.3 0.4 31.8 2.8 3.1 7.2 7.5 0.1 6.5 1.0 9.0 5.5 0.1 5.0 1.2 1.6 0.4 257.7 325.0 3.5 4.0 0.0 19.0 1.6 1.1 0.9 0.1 0.9 0.1 2.9 1.2 1.2 0.2 CUL3 ENSG00000036257 "Cullin 3" Q13618 2 224470150-224585397 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Cilium biogenesis/degradation, ER-Golgi transport, Mitosis, Transport, Ubl conjugation pathway" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 224.8" "Cell type enhanced" "Detected in all" "Late spermatids: 309.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB002678 Supported NA NA 65000 "Cluster 49: Eosinophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" "CAB002678: " "unprognostic (1.22e-2)" "unprognostic (2.35e-1)" "unprognostic (7.05e-2)" "unprognostic (6.29e-2)" "unprognostic (2.82e-1)" "unprognostic (7.03e-2)" "unprognostic (2.70e-2)" "unprognostic (1.13e-1)" "unprognostic (2.53e-3)" "unprognostic (2.65e-2)" "unprognostic (1.01e-2)" "unprognostic (6.16e-2)" "unprognostic (4.86e-3)" "unprognostic (2.16e-2)" "unprognostic (8.74e-3)" "unprognostic (9.61e-2)" "unprognostic (1.87e-2)" 30.6 33.6 26.7 36.3 28.2 62.5 40.6 30.4 34.7 35.3 31.0 38.2 36.1 33.6 41.8 54.2 28.7 32.8 39.0 28.6 30.2 49.4 52.4 31.2 55.5 25.9 26.0 33.2 34.3 56.5 25.2 37.1 26.2 33.4 39.4 46.3 36.1 28.6 112.6 54.1 34.2 33.5 27.0 33.8 35.5 224.8 26.6 48.4 45.7 81.8 75.7 40.6 36.5 31.1 61.7 61.3 87.8 72.6 71.9 62.7 82.7 73.9 74.3 72.6 67.7 72.7 60.2 67.0 44.5 76.1 70.3 53.6 99.8 85.0 112.0 66.5 54.5 95.9 61.3 100.7 87.6 95.1 69.3 62.6 68.9 67.7 74.0 72.2 74.3 61.9 90.2 67.0 96.9 104.5 88.5 91.5 90.4 100.9 38.0 76.5 109.8 50.0 108.5 141.0 79.9 58.6 51.1 73.7 85.7 124.5 58.6 79.3 66.2 77.2 58.5 52.1 74.1 69.2 55.3 115.3 59.9 58.2 83.7 9.4 2.8 7.6 3.5 3.5 4.6 5.3 3.9 5.4 3.0 6.5 4.7 5.2 6.6 8.7 4.2 3.6 7.6 1.7 26.7 28.2 30.4 34.7 28.6 30.2 25.9 26.0 26.2 27.0 26.6 31.1 48.3 51.3 69.6 92.1 73.9 28.3 67.8 25.1 20.5 48.5 40.8 34.7 39.9 30.0 49.7 27.6 29.2 25.7 85.3 46.7 35.2 20.2 211.2 58.9 66.9 35.2 40.9 30.9 86.7 24.9 17.8 35.0 32.6 76.2 38.0 37.1 28.5 39.6 20.7 60.6 93.4 39.2 20.3 43.2 28.3 309.7 27.4 45.2 24.9 95.5 39.4 48.4 28.8 107.1 126.4 34.5 39.3 27.4 58.1 59.8 43.8 43.2 38.7 41.3 52.6 71.8 41.5 116.4 50.7 35.7 32.7 39.5 61.2 40.1 34.0 90.1 CXCL9 "CMK, crg-10, Humig, MIG, SCYB9" ENSG00000138755 "C-X-C motif chemokine ligand 9" Q07325 4 76001275-76007509 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "lymphoid tissue: 309.9" "Cell type enhanced" "Detected in some" "Hepatic stellate cells: 5.0;Hofbauer cells: 6.2;Kupffer cells: 10.3;Macrophages: 12.6;Spermatogonia: 8.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 8 "RPMI-8226: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 902000 "Cluster 14: Monocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 41: Macrophages - Immune response" "prognostic favorable (6.36e-4)" "unprognostic (6.86e-3)" "unprognostic (1.25e-2)" "prognostic favorable (2.07e-4)" "unprognostic (2.97e-1)" "unprognostic (3.78e-3)" "unprognostic (8.79e-2)" "unprognostic (4.93e-2)" "unprognostic (1.46e-2)" "prognostic favorable (8.06e-4)" "unprognostic (2.18e-3)" "unprognostic (1.88e-1)" "prognostic unfavorable (5.15e-6)" "unprognostic (4.76e-2)" "unprognostic (4.14e-2)" "unprognostic (1.57e-2)" "unprognostic (6.54e-2)" 5.5 2.0 0.1 65.1 0.2 0.2 17.5 0.1 0.6 4.9 0.3 10.2 3.0 4.8 0.7 5.3 2.8 8.5 5.9 0.1 0.1 8.7 19.1 31.8 309.9 1.8 0.2 3.8 1.4 1.5 1.0 1.7 1.6 3.7 25.3 0.0 19.0 0.7 1.5 2.9 6.0 3.2 0.3 31.2 17.5 6.0 0.2 32.8 7.1 2.5 30.6 11.1 1.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.2 0.1 0.6 0.1 0.1 1.8 0.2 1.6 0.3 0.2 0.3 3.4 0.0 1.7 0.0 2.6 0.0 0.0 0.1 0.0 0.0 0.4 0.3 0.7 0.0 0.0 1.8 0.0 0.0 0.2 0.4 0.0 0.2 1.3 0.1 1.1 2.1 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.1 0.0 0.0 5.0 1.8 6.2 0.0 0.0 0.0 0.0 10.3 3.6 1.3 0.6 12.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.1 3.5 1.7 8.0 0.0 0.3 0.1 0.5 0.0 0.1 0.4 CXCR4 "CD184, D2S201E, fusin, HM89, HSY3RR, LESTR, NPY3R, NPYR, NPYY3R" ENSG00000121966 "C-X-C motif chemokine receptor 4" P61073 2 136114349-136118149 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "Host-virus interaction" "G-protein coupled receptor, Host cell receptor for virus entry, Receptor, Transducer" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 1175.1;lymphoid tissue: 549.3" "Cell type enhanced" "Detected in many" "B-cells: 1446.9;dendritic cells: 1015.1;Langerhans cells: 486.2;Macrophages: 513.6;Plasma cells: 534.2;T-cells: 1436.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 580.8;JURKAT: 323.6;Karpas-707: 302.1;MOLT-4: 538.9;REH: 281.0;U-266/70: 648.5;U-698: 677.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "unprognostic (1.19e-1)" "unprognostic (1.46e-2)" "unprognostic (2.69e-1)" "unprognostic (5.97e-2)" "unprognostic (1.29e-2)" "unprognostic (1.12e-2)" "unprognostic (4.99e-2)" "unprognostic (9.25e-2)" "unprognostic (6.06e-2)" "prognostic favorable (2.05e-4)" "unprognostic (1.23e-1)" "unprognostic (2.66e-1)" "prognostic unfavorable (1.41e-7)" "prognostic unfavorable (5.67e-4)" "unprognostic (1.57e-1)" "unprognostic (3.47e-2)" "unprognostic (9.33e-2)" 51.8 184.5 11.8 297.9 11.4 1175.1 39.6 14.6 23.8 36.1 20.1 33.2 12.6 35.2 5.5 34.9 64.9 84.5 21.8 10.6 19.7 29.0 52.4 95.5 383.8 24.3 12.8 12.9 10.0 12.3 32.6 57.5 18.2 34.1 48.6 7.8 30.2 11.8 5.2 9.8 246.5 28.1 16.7 346.5 64.0 4.0 15.2 491.2 36.7 12.0 549.3 99.3 26.9 32.3 0.8 0.3 9.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.9 0.0 580.8 1.8 0.0 0.4 0.7 1.7 0.0 0.0 29.6 6.9 35.1 84.3 0.0 0.0 81.5 60.7 0.0 0.0 0.0 0.0 0.0 54.5 323.6 1.0 302.1 0.0 1.5 538.9 72.8 9.3 45.4 2.9 281.0 62.6 102.5 4.5 0.0 30.9 26.1 0.6 2.0 0.3 2.9 0.7 156.7 8.1 0.0 2.0 0.5 0.4 648.5 116.7 677.4 0.1 131.8 0.1 87.0 28.5 117.8 83.8 15.6 67.3 115.6 76.5 79.6 25.7 166.2 113.1 109.5 143.3 17.2 9.1 63.7 76.1 51.9 11.8 11.4 14.6 23.8 10.6 19.7 24.3 12.8 18.2 16.7 15.2 32.3 32.0 16.0 42.2 8.5 1446.9 41.0 5.7 0.3 9.6 8.6 46.1 42.2 5.2 11.5 4.4 3.7 0.0 1.5 1015.1 1.1 13.7 5.1 1.2 20.0 8.9 67.6 1.8 67.5 0.0 0.9 4.2 28.9 52.0 71.0 12.6 9.0 29.6 9.1 159.9 0.0 0.2 2.0 10.2 270.0 486.2 2.9 1.5 513.6 113.8 3.7 189.2 1.0 153.5 0.0 2.0 2.3 1.1 2.6 534.2 3.2 0.0 3.2 2.4 0.8 46.0 99.1 23.1 0.5 7.8 8.5 35.7 6.3 1436.5 4.6 1.8 4.5 CXorf65 ENSG00000204165 "Chromosome X open reading frame 65" A6NEN9 X 71103889-71106788 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "testis: 22.4" "Group enriched" "Detected in some" 154 "Early spermatids: 432.7;Late spermatids: 1481.8" "Cancer enhanced" "Detected in some" "melanoma: 1.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047396 Uncertain NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 31: Spermatids - Spermatogenesis" "HPA047396: AB_2680028" "unprognostic (7.81e-3)" "unprognostic (8.43e-4)" "unprognostic (1.08e-2)" "unprognostic (1.87e-2)" "unprognostic (6.14e-2)" "unprognostic (3.06e-3)" "unprognostic (6.20e-2)" "unprognostic (2.62e-2)" "unprognostic (6.72e-2)" "unprognostic (1.84e-4)" "unprognostic (9.53e-2)" "unprognostic (1.36e-1)" "unprognostic (1.44e-8)" "unprognostic (1.12e-1)" "unprognostic (3.49e-2)" "unprognostic (7.30e-2)" "unprognostic (1.25e-3)" 0.2 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 1.1 0.0 0.0 2.3 0.1 22.4 0.0 0.0 0.1 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.7 0.6 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.4 0.8 0.0 0.0 432.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.6 0.0 0.0 0.4 0.0 0.6 2.1 1481.8 4.4 0.5 1.8 1.0 0.2 0.0 6.2 0.0 0.0 0.0 0.2 6.0 0.3 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 4.4 2.7 0.0 0.0 1.1 3.2 0.0 0.1 0.1 CXXC4 IDAX ENSG00000168772 "CXXC finger protein 4" 4 104468308-104494901 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 16.1;retina: 7.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 48.0;Cone photoreceptor cells: 31.3;Enteroendocrine cells: 102.1;Horizontal cells: 45.4;Oligodendrocyte precursor cells: 64.3;Oligodendrocytes: 30.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 7.0;AN3-CA: 9.7;Karpas-707: 9.0;RPMI-8226: 5.5;SCLC-21H: 12.0;U-266/70: 9.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036600, HPA036925" Uncertain Uncertain "Nucleoplasm,Golgi apparatus" NA NA "Cluster 58: Brain - Synaptic function" "Cluster 12: NES - Nervous system development" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Golgi apparatus" Nucleoplasm "HPA036600: AB_10673659, HPA036925: " "unprognostic (1.37e-2)" "unprognostic (1.12e-1)" "unprognostic (5.75e-2)" "unprognostic (5.86e-2)" "unprognostic (9.07e-3)" "unprognostic (1.14e-1)" "unprognostic (1.75e-2)" "unprognostic (9.69e-3)" "unprognostic (2.75e-1)" "unprognostic (2.45e-1)" "prognostic favorable (2.19e-4)" "unprognostic (1.82e-1)" "unprognostic (4.52e-3)" "unprognostic (5.69e-2)" "unprognostic (1.37e-1)" "unprognostic (2.38e-1)" "unprognostic (4.42e-3)" 0.6 1.3 4.9 0.1 3.9 0.0 1.4 3.0 16.1 0.7 0.2 1.3 1.8 0.4 1.7 0.1 2.3 0.3 1.9 4.3 10.1 0.4 0.8 0.6 0.0 5.0 6.1 1.8 3.0 0.7 4.4 0.3 4.5 0.5 0.8 7.3 2.9 0.4 0.3 0.2 1.9 0.4 4.4 0.4 1.3 1.6 11.9 0.5 2.4 0.1 0.0 0.2 0.3 4.8 0.0 0.2 7.0 9.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 2.8 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.4 0.0 0.9 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.1 0.0 9.0 0.0 0.0 2.7 0.0 2.5 0.1 0.1 0.0 0.0 5.5 0.0 0.1 12.0 2.2 0.0 0.6 0.0 2.8 0.3 0.0 0.0 0.0 1.5 0.0 0.1 9.7 2.6 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.9 3.9 3.0 16.1 4.3 10.1 5.0 6.1 4.5 4.4 11.9 4.8 12.4 0.0 6.4 10.4 0.1 0.3 1.0 0.8 1.2 48.0 8.4 5.6 15.9 2.8 2.2 0.0 31.3 0.2 0.8 0.4 0.0 0.1 0.3 13.0 0.9 2.9 102.1 0.0 23.8 3.3 0.0 1.0 0.0 0.6 0.0 1.2 1.1 2.7 0.1 45.4 27.5 6.2 0.0 0.3 0.3 0.9 0.3 0.1 1.8 0.0 0.0 13.8 1.0 64.3 30.8 1.5 1.2 10.9 0.3 0.6 10.2 1.1 12.6 26.7 0.0 15.6 0.9 0.0 4.8 0.1 0.0 0.3 0.5 0.1 2.6 0.5 CYB5D1 FLJ32499 ENSG00000182224 "Cytochrome b5 domain containing 1" Q6P9G0 17 7857746-7862282 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 71.9;Endometrial ciliated cells: 45.5;Late spermatids: 42.6;Respiratory ciliated cells: 47.3;Skeletal myocytes: 41.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021632 Uncertain Approved "Nucleoli,Golgi apparatus" NA NA "Cluster 30: Non-specific - Translation" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" "Nucleoli, Golgi apparatus" "HPA021632: AB_1847368" "unprognostic (1.99e-1)" "unprognostic (2.91e-1)" "unprognostic (1.23e-1)" "unprognostic (5.10e-3)" "unprognostic (2.34e-1)" "unprognostic (4.44e-3)" "unprognostic (1.12e-1)" "unprognostic (2.16e-2)" "unprognostic (1.34e-1)" "unprognostic (2.69e-2)" "unprognostic (2.89e-2)" "unprognostic (2.41e-2)" "unprognostic (1.04e-4)" "unprognostic (2.38e-2)" "unprognostic (1.25e-1)" "unprognostic (5.27e-3)" "unprognostic (1.79e-2)" 17.2 13.0 8.6 5.5 9.4 7.8 12.1 9.6 9.7 10.2 16.0 9.4 6.2 10.1 15.2 8.2 26.4 8.7 15.0 9.0 10.1 17.9 12.6 8.3 4.8 10.0 10.8 13.0 11.4 10.8 16.6 6.6 9.0 11.3 7.1 30.0 10.3 11.6 10.6 9.6 6.3 8.7 9.3 6.0 8.8 8.8 11.5 7.5 21.3 13.6 5.4 7.4 7.8 8.0 24.6 17.9 8.5 22.4 14.8 13.0 5.0 12.5 12.2 13.0 12.4 11.3 4.6 10.5 8.6 10.0 7.6 21.3 18.9 16.1 19.4 7.1 21.9 6.9 24.6 16.3 6.7 12.4 4.7 11.2 19.9 22.8 20.2 8.0 14.0 25.3 5.2 7.0 7.3 10.7 19.5 5.0 10.7 16.0 18.2 13.2 3.9 10.7 20.4 4.7 11.4 7.6 19.9 10.8 11.6 8.5 12.6 5.0 9.9 9.9 8.7 17.8 15.9 3.7 9.7 5.8 20.8 6.7 6.5 0.3 0.9 0.0 1.0 0.7 1.1 1.2 0.8 0.5 1.2 0.5 2.1 1.1 0.9 0.6 0.4 0.5 0.8 0.7 8.6 9.4 9.6 9.7 9.0 10.1 10.0 10.8 9.0 9.3 11.5 8.0 21.8 12.8 19.5 5.9 4.5 5.1 6.7 4.9 1.8 4.8 22.2 18.4 0.3 7.2 11.0 5.5 20.9 4.2 7.7 5.0 13.7 4.2 71.9 45.5 16.3 14.7 6.0 0.8 6.8 3.1 2.7 13.2 13.3 27.2 10.8 4.6 6.8 8.3 3.9 1.7 5.9 8.5 4.1 1.6 4.3 42.6 4.7 29.1 5.4 2.8 0.3 6.7 0.0 0.5 2.2 7.7 4.5 3.8 5.1 7.8 4.5 11.9 47.3 20.3 6.6 41.9 7.5 4.4 2.7 8.5 6.1 2.6 4.4 2.9 8.3 2.5 CYB5D2 MGC32124 ENSG00000167740 "Cytochrome b5 domain containing 2" Q8WUJ1 17 4143168-4187310 "Predicted intracellular proteins, Predicted secreted proteins" Neurogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 130.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 74.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011032, HPA042299" Approved Approved "Endoplasmic reticulum,Plasma membrane" "Secreted to blood" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" "Endoplasmic reticulum, Plasma membrane" "HPA011032: , HPA042299: AB_10793879" "unprognostic (2.57e-2)" "unprognostic (2.89e-2)" "unprognostic (4.16e-2)" "prognostic favorable (6.19e-4)" "unprognostic (1.88e-2)" "unprognostic (1.75e-2)" "prognostic favorable (4.98e-6)" "unprognostic (1.57e-1)" "unprognostic (2.47e-1)" "unprognostic (9.71e-3)" "prognostic favorable (7.76e-5)" "unprognostic (2.04e-1)" "prognostic favorable (2.03e-10)" "unprognostic (2.01e-3)" "unprognostic (8.73e-2)" "unprognostic (1.82e-1)" "unprognostic (2.97e-1)" 19.0 21.7 17.4 6.1 17.3 4.3 18.2 17.4 20.1 15.9 14.2 10.7 15.2 15.6 28.5 10.9 18.7 16.3 14.0 16.7 19.6 25.5 29.0 9.7 9.3 18.1 17.6 20.8 19.7 30.9 24.1 10.8 17.8 13.5 7.4 9.2 20.0 17.6 16.2 14.4 12.1 8.4 17.6 9.6 16.0 29.3 17.9 10.2 22.7 14.9 7.2 12.9 11.7 18.7 16.2 21.6 11.8 12.7 74.7 22.5 5.2 15.7 31.5 11.0 10.9 6.3 10.3 5.3 13.6 17.4 9.2 22.5 4.9 7.1 4.4 17.9 25.7 5.0 13.5 10.5 13.7 2.1 9.5 28.8 17.0 6.2 11.7 22.3 20.1 11.5 5.1 31.2 8.3 20.6 7.8 3.4 4.3 13.7 11.5 9.2 10.6 12.5 25.1 8.5 9.3 8.1 17.2 9.9 23.5 13.1 25.6 3.2 28.5 15.7 4.0 14.5 8.0 5.8 4.9 3.9 19.9 4.5 6.2 0.6 10.8 13.6 5.9 9.2 6.7 8.1 9.3 7.4 10.5 7.1 8.6 8.0 9.5 5.5 8.7 11.3 11.2 8.2 17.4 17.3 17.4 20.1 16.7 19.6 18.1 17.6 17.8 17.6 17.9 18.7 57.4 12.8 10.3 9.1 17.2 53.7 18.4 36.0 12.5 26.9 35.4 36.7 9.8 45.8 21.8 31.3 58.4 55.7 11.4 18.5 52.8 34.3 28.5 36.6 20.0 34.4 13.8 33.3 7.6 27.0 29.1 23.8 19.4 23.4 11.4 22.3 41.0 32.9 21.4 40.4 10.4 16.0 36.7 24.0 23.8 30.6 28.9 17.3 14.2 4.7 15.4 37.6 15.5 8.5 10.0 26.9 18.9 28.6 17.6 8.3 39.7 55.7 38.5 30.4 0.0 15.2 20.1 130.3 29.2 9.5 42.9 38.6 15.8 39.3 16.6 15.8 CYBA p22-PHOX ENSG00000051523 "Cytochrome b-245 alpha chain" P13498 16 88643289-88651054 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Electron transport, Transport" Oxidoreductase "Chronic granulomatous disease, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 742.0;lymphoid tissue: 693.1" "Cell type enhanced" "Detected in many" "dendritic cells: 1632.1;Hofbauer cells: 2171.9;Kupffer cells: 1734.2;Macrophages: 1682.8;monocytes: 1688.5;NK-cells: 1805.4;Plasma cells: 1990.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 733.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MCF7: 1058.3;RPMI-8226: 1631.2;THP-1: 1231.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB009492 Enhanced NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" "CAB009492: AB_2090309" "prognostic favorable (8.19e-4)" "unprognostic (1.05e-1)" "unprognostic (8.32e-2)" "prognostic favorable (4.75e-5)" "unprognostic (2.42e-1)" "unprognostic (4.77e-2)" "unprognostic (4.88e-2)" "unprognostic (9.16e-2)" "unprognostic (1.72e-1)" "unprognostic (1.11e-1)" "unprognostic (3.08e-2)" "unprognostic (2.68e-1)" "prognostic unfavorable (1.83e-4)" "unprognostic (1.91e-1)" "unprognostic (5.22e-2)" "unprognostic (2.57e-2)" "unprognostic (1.63e-2)" 149.9 68.0 40.3 344.4 41.8 742.0 93.3 46.0 58.0 81.9 62.4 200.9 196.6 60.8 38.5 80.9 95.4 122.5 93.2 38.6 55.0 187.7 71.5 234.6 333.8 73.8 49.3 40.0 108.6 13.4 40.6 54.9 64.1 75.2 79.9 1.8 116.7 26.6 41.8 39.4 245.3 51.3 65.4 693.1 236.0 10.4 62.4 87.1 136.5 19.9 192.8 144.6 74.1 92.2 2.5 663.0 2.6 1.5 1.3 0.4 329.5 155.7 77.3 39.3 24.1 447.2 819.6 510.5 420.7 56.4 0.0 250.5 21.4 0.9 5.8 146.1 564.1 99.0 217.7 694.9 75.7 156.3 397.6 80.7 0.0 1.6 0.3 1.9 23.9 103.6 278.5 567.5 3.2 1058.3 147.9 822.3 106.2 248.7 1.5 437.9 1.6 1631.2 324.9 490.9 84.2 76.5 482.7 78.8 138.5 60.8 1.4 1231.3 129.8 1.5 6.1 1.8 2.2 362.9 459.9 543.6 195.5 464.9 53.4 120.2 103.8 733.7 76.7 150.1 55.8 109.8 36.7 70.4 107.0 110.7 28.9 36.7 192.3 36.4 143.3 196.3 41.2 47.3 40.3 41.8 46.0 58.0 38.6 55.0 73.8 49.3 64.1 65.4 62.4 92.2 157.8 16.0 12.4 0.0 1290.9 119.4 233.4 420.8 53.5 0.4 131.7 133.2 12.8 368.9 487.1 285.1 2.1 45.3 1632.1 807.2 127.2 636.8 4.2 219.5 137.5 137.1 230.5 162.7 0.2 155.3 299.0 184.8 285.4 312.5 279.0 104.3 317.0 23.9 2171.9 0.0 0.2 540.3 233.9 1734.2 1370.8 14.0 50.1 1682.8 1152.6 32.8 1688.5 1.6 1805.4 1.0 0.2 682.8 1045.8 21.4 1990.6 191.8 390.4 1057.4 529.7 2.7 59.2 44.0 164.3 0.9 15.6 75.2 85.7 118.2 838.6 20.5 805.2 436.9 CYFIP2 PIR121 ENSG00000055163 "Cytoplasmic FMR1 interacting protein 2" Q96F07 5 157266079-157395595 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Cell adhesion" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 112.2;kidney: 139.9" "Cell type enhanced" "Detected in many" "Astrocytes: 133.5;Collecting duct cells: 158.2;Distal tubular cells: 174.1;Excitatory neurons: 117.7;Inhibitory neurons: 147.5;Oligodendrocyte precursor cells: 120.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 202.4;JURKAT: 145.2;MOLT-4: 204.8;U-266/70: 153.6;U-698: 142.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB055519, HPA068106, HPA071459" Uncertain Approved "Endoplasmic reticulum,Plasma membrane,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 59: Non-specific - Transcription" "Endoplasmic reticulum" "Plasma membrane, Cytosol" "CAB055519: , HPA068106: AB_2685955, HPA071459: AB_2686400" "unprognostic (1.02e-2)" "unprognostic (1.30e-1)" "unprognostic (7.07e-2)" "prognostic unfavorable (2.42e-6)" "unprognostic (3.76e-1)" "unprognostic (4.58e-2)" "unprognostic (1.14e-1)" "unprognostic (6.91e-3)" "unprognostic (3.97e-2)" "unprognostic (5.25e-2)" "prognostic favorable (1.18e-4)" "unprognostic (3.81e-2)" "prognostic favorable (3.21e-12)" "unprognostic (2.90e-1)" "unprognostic (1.38e-1)" "unprognostic (3.03e-1)" "unprognostic (2.49e-2)" 3.2 12.3 61.0 30.8 54.4 55.5 2.8 23.6 103.8 3.1 16.3 8.9 6.3 6.6 25.1 3.8 9.2 8.8 10.4 112.2 25.6 139.9 18.3 12.2 57.1 8.4 33.4 4.8 7.1 64.9 40.1 9.3 6.6 5.8 9.8 35.4 4.0 5.0 7.0 2.8 17.5 5.6 0.0 35.0 20.9 5.3 67.7 85.9 9.9 1.7 55.3 8.3 2.3 37.7 0.3 31.8 47.3 28.8 1.1 1.3 81.5 6.1 9.6 2.5 6.8 6.2 0.6 202.4 14.5 3.4 7.4 0.4 38.0 27.1 5.8 48.8 60.8 28.4 42.3 24.9 4.1 29.1 71.8 5.4 10.9 8.1 0.5 18.8 8.8 145.2 0.4 81.1 7.0 7.7 204.8 5.5 22.3 0.5 8.5 50.6 1.4 102.3 24.5 30.2 70.5 27.4 0.6 28.3 4.6 46.8 19.9 0.8 11.3 2.0 21.4 7.1 5.4 153.6 40.2 142.8 21.4 33.5 11.8 64.8 12.6 90.1 85.9 57.4 61.0 35.8 60.6 75.7 17.8 35.9 63.2 73.2 41.0 53.9 133.7 43.9 53.5 78.0 61.0 54.4 23.6 103.8 112.2 25.6 8.4 33.4 6.6 0.0 67.7 37.7 1.8 3.2 26.9 133.5 76.6 1.1 2.2 2.8 3.4 62.0 3.5 3.4 17.9 8.6 7.4 158.2 16.7 37.2 78.8 6.0 174.1 9.7 15.3 2.8 1.8 2.6 14.4 11.6 117.7 1.6 43.0 3.6 6.1 6.2 2.5 23.1 5.7 30.8 5.3 90.9 147.5 5.6 4.1 6.5 11.4 24.2 1.8 15.7 7.2 23.4 20.3 14.0 101.0 120.6 33.8 1.9 9.9 6.8 41.1 1.3 5.4 55.0 4.7 35.2 0.0 12.2 11.0 3.2 13.1 0.8 1.4 21.1 88.8 2.1 9.1 1.7 CYP11A1 "CYP11A, P450SCC" ENSG00000140459 "Cytochrome P450 family 11 subfamily A member 1" P05108 15 74337759-74367646 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Steroidogenesis, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 26 "adrenal gland: 1009.9" "Cell type enhanced" "Detected in some" "Extravillous trophoblasts: 345.1;Peritubular cells: 173.8;Syncytiotrophoblasts: 1452.0;Theca cells: 637.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 48 "basophil: 10.2" "Lineage enriched" "Detected in single" 48 "granulocytes: 10.2" "Group enriched" "Detected in some" 5 "BEWO: 55.2;HEL: 46.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basal ganglia: 1.8;hippocampal formation: 1.1;hypothalamus: 1.3;midbrain: 4.5;pons: 1.1" HPA016436 Enhanced NA NA "Cluster 46: Basophils - DNA binding" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "HPA016436: AB_1847423" "unprognostic (8.89e-2)" "unprognostic (6.96e-2)" "unprognostic (4.95e-3)" "unprognostic (9.31e-2)" "unprognostic (9.42e-4)" "unprognostic (1.90e-1)" "unprognostic (1.55e-3)" "unprognostic (8.06e-2)" "unprognostic (3.04e-1)" "unprognostic (2.95e-1)" "unprognostic (1.77e-2)" "unprognostic (5.45e-2)" "unprognostic (9.66e-4)" "unprognostic (2.40e-2)" "unprognostic (2.74e-1)" "unprognostic (3.04e-2)" "unprognostic (7.95e-2)" 2.0 1009.9 2.0 0.6 2.1 0.1 1.9 2.3 2.0 2.0 3.5 0.8 0.3 1.6 0.8 6.3 2.4 0.4 1.4 2.0 2.1 0.6 3.6 0.6 0.1 2.8 2.5 38.9 0.3 0.0 2.8 25.2 2.8 1.2 0.2 0.7 1.2 0.5 2.5 0.6 0.8 0.9 2.6 4.9 0.9 23.0 1.9 0.3 0.3 1.0 2.1 0.5 1.0 1.9 0.0 0.0 0.0 0.2 0.0 0.4 55.2 0.1 0.0 0.4 0.1 0.0 0.0 0.0 1.3 0.1 0.2 0.0 0.0 0.0 0.3 0.0 0.2 46.8 1.2 0.5 0.2 0.0 0.2 1.9 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 11.1 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.1 0.0 0.0 0.1 0.1 0.0 10.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.0 2.1 2.3 2.0 2.0 2.1 2.8 2.5 2.8 2.6 1.9 1.9 0.1 0.0 0.0 6.2 0.0 0.3 0.0 0.0 34.1 0.1 0.6 0.9 1.2 2.8 0.0 0.0 0.0 144.6 0.0 0.0 1.9 0.0 1.6 0.2 4.9 0.8 0.0 0.0 0.2 0.0 345.1 10.0 0.0 0.2 0.0 41.3 0.0 3.6 22.0 0.0 0.2 0.0 0.0 0.0 0.0 6.7 48.7 0.4 0.0 1.0 0.6 6.2 0.0 0.0 0.2 0.5 0.0 173.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 1.2 4.6 2.8 8.7 0.0 1452.0 0.0 637.4 0.0 0.0 CYP11B1 "CPN1, CYP11B, FHI, P450C11" ENSG00000160882 "Cytochrome P450 family 11 subfamily B member 1" P15538 8 142872356-142879846 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroidogenesis" "Monooxygenase, Oxidoreductase" "Congenital adrenal hyperplasia, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 877 "adrenal gland: 3686.5" "Group enriched" "Detected in some" 113 "Early spermatids: 53.3;Late spermatids: 83.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA049171, HPA049565, HPA056348, HPA057752" Supported Approved Mitochondria NA NA "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria "HPA049171: AB_2680661, HPA049565: , HPA056348: AB_2683104, HPA057752: AB_2683516" 0.2 3686.5 0.1 0.9 0.6 0.0 0.1 0.0 0.1 0.2 0.5 0.2 0.0 0.2 0.0 0.4 0.2 0.0 0.4 0.3 0.0 0.9 0.5 0.3 0.0 0.1 0.1 0.3 0.5 0.0 0.4 0.0 0.0 0.3 0.0 0.0 1.4 0.0 0.2 0.2 0.2 0.0 0.0 0.3 0.4 4.2 0.0 0.0 0.2 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.1 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 53.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 83.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CYP19A1 "ARO, ARO1, aromatase, CPV1, CYAR, CYP19, P-450AROM" ENSG00000137869 "Cytochrome P450 family 19 subfamily A member 1" P11511 15 51208057-51338601 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Cancer-related genes, Disease variant, FDA approved drug targets, Pseudohermaphroditism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "placenta: 124.4" "Cell type enriched" "Detected in some" 10 "Syncytiotrophoblasts: 2007.5" "Cancer enhanced" "Detected in single" "glioma: 0.6" "Group enriched" "Detected in many" 4 "amygdala: 4.8;hypothalamus: 4.1;medulla oblongata: 1.4;midbrain: 2.0;thalamus: 3.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 92.8;HDLM-2: 17.5;HSkMC: 31.4;SuSa: 16.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000355, HPA051194" Enhanced Uncertain Mitochondria NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Mitochondria "CAB000355: , HPA051194: AB_2681381" "unprognostic (9.41e-2)" "unprognostic (7.44e-2)" "unprognostic (9.52e-5)" "unprognostic (6.81e-2)" "unprognostic (2.72e-1)" "unprognostic (4.25e-4)" "unprognostic (5.18e-5)" "unprognostic (1.54e-3)" "unprognostic (2.38e-2)" "unprognostic (2.52e-1)" "unprognostic (1.97e-1)" "unprognostic (5.37e-2)" "unprognostic (1.54e-5)" "unprognostic (2.52e-3)" "unprognostic (2.11e-1)" "unprognostic (1.40e-2)" "unprognostic (1.11e-1)" 8.3 9.0 4.8 0.4 0.6 0.2 2.1 0.1 0.5 0.6 0.0 0.2 0.7 0.3 0.0 0.1 0.3 0.5 1.2 0.3 4.1 0.1 0.1 0.7 0.0 1.4 2.0 3.2 1.3 0.2 0.0 124.4 0.7 0.6 0.1 0.6 0.9 2.7 0.6 1.8 0.2 1.3 0.2 0.6 0.2 6.5 3.7 0.2 2.4 0.3 0.0 3.5 0.5 0.7 0.1 0.0 0.0 0.0 1.7 92.8 6.0 0.1 0.3 0.0 0.1 0.2 0.0 0.0 0.3 0.5 0.4 0.0 0.0 0.0 0.0 17.5 0.0 0.6 0.2 8.1 0.6 0.0 0.1 31.4 0.0 0.3 4.0 0.3 0.0 0.0 0.0 0.8 0.4 0.7 0.0 0.1 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 2.4 0.2 16.3 0.0 0.5 0.1 0.3 0.1 0.2 0.0 3.0 1.6 0.0 0.8 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.8 0.6 0.1 0.5 0.3 4.1 1.4 2.0 0.7 0.2 3.7 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 52.8 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.7 0.0 0.0 0.1 0.0 7.9 1.5 0.0 0.0 0.0 191.3 0.0 0.0 14.0 0.0 0.3 0.0 0.0 0.9 0.0 5.1 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.2 0.9 12.3 0.3 0.0 0.0 2007.5 0.0 22.2 0.0 0.0 CYP39A1 ENSG00000146233 "Cytochrome P450 family 39 subfamily A member 1" Q9NYL5 6 46549580-46652830 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 99.2" "Cell type enhanced" "Detected in many" "Hepatocytes: 62.9;Late spermatids: 20.1" "Cancer enhanced" "Detected in many" "prostate cancer: 11.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 6.5;hTCEpi: 13.6;OE19: 6.1;SiHa: 8.4;U-698: 10.4" "Region enhanced" "Detected in all" "olfactory bulb: 22.9" "Low region specificity" "Detected in all" NA NA "Cluster 85: Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (1.33e-1)" "unprognostic (1.62e-2)" "unprognostic (8.46e-3)" "unprognostic (5.89e-2)" "unprognostic (1.06e-1)" "unprognostic (2.08e-1)" "unprognostic (1.03e-1)" "unprognostic (5.78e-2)" "unprognostic (1.61e-1)" "unprognostic (4.99e-2)" "unprognostic (7.33e-2)" "unprognostic (6.11e-2)" "prognostic favorable (1.86e-4)" "unprognostic (1.54e-1)" "unprognostic (5.48e-2)" "unprognostic (1.43e-1)" "unprognostic (1.20e-1)" 3.0 2.5 2.1 1.0 2.7 0.0 5.4 3.5 2.9 3.7 5.3 2.7 0.8 3.6 21.0 3.3 4.1 6.3 3.9 2.0 2.1 5.7 99.2 3.3 0.5 2.3 2.3 11.5 5.7 15.3 2.9 0.4 2.1 14.8 3.6 4.1 23.5 2.6 0.6 15.9 1.6 2.4 2.4 0.7 2.8 4.2 2.4 0.4 6.1 1.2 1.4 2.7 3.0 2.9 0.2 0.4 0.3 1.8 0.3 0.0 0.0 0.0 1.1 0.3 0.1 0.0 0.5 6.5 4.4 0.0 0.9 1.7 0.8 1.4 0.0 0.0 2.8 0.0 1.7 1.8 4.0 0.0 0.0 0.5 13.6 0.0 1.6 1.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.1 1.5 0.5 1.1 0.1 2.9 4.0 0.7 0.0 8.4 0.0 0.2 0.4 1.5 0.0 0.0 0.2 0.9 0.0 0.1 0.0 0.0 10.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 2.7 3.5 2.9 2.0 2.1 2.3 2.3 2.1 2.4 2.4 2.9 3.3 16.0 1.5 3.9 0.2 4.0 8.8 2.7 2.8 1.4 4.6 6.5 5.8 10.0 4.3 3.7 2.1 0.0 0.0 1.1 5.9 2.9 12.7 4.4 1.0 3.5 0.0 5.3 3.2 0.4 0.9 4.5 1.5 3.1 0.0 2.7 1.1 62.9 0.2 0.0 2.0 4.0 10.2 2.5 0.9 20.1 6.2 0.3 3.6 8.4 0.0 8.6 0.0 1.0 7.2 0.5 2.7 9.4 0.0 7.9 0.3 5.3 7.2 1.5 0.0 1.9 2.3 0.7 0.8 2.6 15.3 0.0 0.2 6.3 2.5 8.1 CYTH4 "CYT4, cytohesin-4, PSCD4" ENSG00000100055 "Cytohesin 4" Q9UIA0 22 37282027-37315341 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 58.3;lymphoid tissue: 67.3" "Cell type enhanced" "Detected in many" "dendritic cells: 117.5;granulocytes: 57.0;Hofbauer cells: 76.8;Kupffer cells: 71.5;Langerhans cells: 87.5;Macrophages: 55.0;NK-cells: 120.5;T-cells: 43.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HL-60: 34.1;HMC-1: 141.1;THP-1: 95.2;U-266/70: 28.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004065, HPA071573" Approved Supported "Plasma membrane,Cytokinetic bridge,Centriolar satellite,Cytosol" Yes NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Cytokinetic bridge, Centriolar satellite, Cytosol" "HPA004065: , HPA071573: AB_2686418" "unprognostic (4.30e-3)" "unprognostic (1.65e-2)" "unprognostic (3.03e-2)" "unprognostic (9.28e-3)" "unprognostic (9.25e-2)" "unprognostic (1.69e-2)" "unprognostic (1.50e-1)" "unprognostic (5.84e-2)" "unprognostic (3.30e-3)" "unprognostic (1.23e-1)" "unprognostic (3.31e-2)" "unprognostic (8.42e-2)" "prognostic unfavorable (2.41e-8)" "unprognostic (3.70e-2)" "unprognostic (1.92e-2)" "unprognostic (5.56e-2)" "unprognostic (2.07e-1)" 21.5 8.8 4.9 67.3 4.5 58.3 5.1 4.4 8.5 5.3 6.0 10.7 8.5 4.4 1.6 6.1 4.8 16.4 5.6 4.7 5.6 4.1 5.7 18.9 57.0 8.8 7.4 3.4 2.5 2.1 2.9 28.0 7.8 3.6 10.0 0.3 7.3 4.3 2.2 2.2 15.2 12.9 6.7 59.2 11.5 2.7 9.7 25.6 3.0 5.1 40.3 23.2 2.5 9.1 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.8 9.3 0.3 0.0 2.5 0.1 0.0 0.6 0.0 5.3 0.0 9.8 0.0 0.0 0.0 34.1 141.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 23.2 0.0 0.0 0.5 13.5 0.0 0.1 1.0 1.3 0.2 19.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 95.2 0.3 0.0 0.1 0.1 0.0 28.4 4.0 4.5 18.5 11.5 0.2 15.8 62.6 87.5 55.4 102.5 39.0 30.3 30.5 44.8 47.5 31.8 30.0 38.3 199.1 45.0 129.4 113.8 30.7 76.2 4.9 4.5 4.4 8.5 4.7 5.6 8.8 7.4 7.8 6.7 9.7 9.1 1.1 3.2 8.4 0.0 37.0 2.4 0.8 0.0 0.6 0.1 0.7 1.5 2.0 0.0 1.8 0.0 0.0 0.5 117.5 0.1 0.0 0.0 0.4 0.1 0.2 2.5 0.0 2.5 0.2 0.2 0.6 1.9 2.0 0.1 57.0 0.0 2.2 1.1 76.8 0.0 0.2 0.2 0.0 71.5 87.5 0.9 0.6 55.0 7.2 24.4 42.7 0.0 120.5 0.5 0.0 0.8 0.0 0.0 25.1 0.3 0.0 0.8 0.0 0.1 0.0 0.9 1.0 0.0 0.2 0.3 2.3 1.0 43.9 0.0 0.2 0.5 CYYR1 C21orf95 ENSG00000166265 "Cysteine and tyrosine rich 1" Q96J86 21 26466209-26573286 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Adipocytes: 200.0;Endothelial cells: 150.0;Hepatic stellate cells: 79.9;Microglial cells: 58.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 38 "plasmacytoid DC: 31.4" "Lineage enriched" "Detected in single" 82 "dendritic cells: 31.4" "Cell line enhanced" "Detected in some" "AF22: 14.1;NTERA-2: 39.2;PC-3: 11.0;RH-30: 16.6;SCLC-21H: 33.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034921, HPA067685" Uncertain Approved Nucleoplasm NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "CAB034921: AB_2089315, HPA067685: AB_2685887" "unprognostic (5.64e-2)" "unprognostic (2.59e-2)" "unprognostic (1.37e-1)" "unprognostic (1.88e-1)" "unprognostic (7.00e-2)" "unprognostic (2.63e-2)" "unprognostic (2.88e-3)" "unprognostic (4.04e-1)" "unprognostic (1.11e-2)" "unprognostic (1.12e-1)" "unprognostic (3.77e-2)" "unprognostic (1.46e-1)" "unprognostic (2.44e-3)" "unprognostic (9.29e-3)" "unprognostic (2.26e-1)" "unprognostic (1.88e-1)" "unprognostic (1.49e-2)" 36.4 46.4 9.7 8.1 9.0 7.8 30.2 8.7 11.4 16.4 8.4 8.4 6.1 19.2 8.1 9.0 12.9 16.1 22.3 8.1 9.4 12.7 4.8 23.7 6.0 9.9 10.5 4.5 5.5 15.5 3.8 36.3 10.6 9.5 6.6 0.9 6.8 11.4 15.1 8.2 9.6 23.6 9.6 32.5 7.7 1.9 10.8 6.0 14.1 31.8 4.6 12.6 9.5 9.4 0.0 0.0 14.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 7.1 1.6 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 6.5 0.0 0.4 0.0 5.6 0.0 0.0 0.0 2.6 0.0 0.0 0.1 39.2 0.0 11.0 0.0 16.6 0.0 1.7 0.0 33.7 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 3.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.3 0.0 0.0 31.4 0.0 0.1 9.7 9.0 8.7 11.4 8.1 9.4 9.9 10.5 10.6 9.6 10.8 9.4 200.0 0.0 0.6 1.6 1.5 11.7 2.0 10.2 27.3 0.1 14.9 15.0 6.7 0.0 1.7 14.7 0.0 0.1 14.9 0.0 3.9 0.0 0.7 0.4 6.9 150.0 0.0 11.1 1.6 0.0 0.2 8.3 0.0 0.4 0.0 3.7 79.9 0.4 0.3 0.0 4.6 0.0 2.0 3.2 8.0 1.5 2.1 1.4 7.2 58.1 0.7 0.5 0.0 0.0 0.7 0.1 0.0 0.0 2.5 1.1 0.0 6.8 1.1 0.3 0.0 13.3 4.4 0.2 1.3 4.9 5.4 0.3 1.5 0.4 0.0 0.7 DACH1 DACH ENSG00000276644 "Dachshund family transcription factor 1" Q9UI36 13 71437966-71867204 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 88.5;Excitatory neurons: 77.0;Horizontal cells: 87.5;Late spermatids: 103.7;Microglial cells: 143.4;Muller glia cells: 143.8;Spermatocytes: 58.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 15 "basophil: 4.2;eosinophil: 8.4;NK-cell: 4.2;plasmacytoid DC: 6.4" "Group enriched" "Detected in many" 33 "dendritic cells: 6.4;granulocytes: 8.4;NK-cells: 4.2" "Cell line enhanced" "Detected in some" "AF22: 14.2;HAP1: 22.5;HEK 293: 16.8;HL-60: 37.9;NB-4: 16.7;SCLC-21H: 36.9;SH-SY5Y: 29.5;THP-1: 26.9" "Region enriched" "Detected in all" 5 "basal ganglia: 38.8" "Region enriched" "Detected in all" 5 "basal ganglia: 34.2" "HPA012672, HPA012938, HPA073222" Approved Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Nuclear speckles" "HPA012672: AB_1847466, HPA012938: , HPA073222: " "unprognostic (3.16e-1)" "unprognostic (5.26e-2)" "unprognostic (1.41e-2)" "unprognostic (2.36e-1)" "unprognostic (4.21e-2)" "unprognostic (5.63e-2)" "unprognostic (2.22e-2)" "unprognostic (8.08e-3)" "unprognostic (2.12e-2)" "unprognostic (2.50e-1)" "unprognostic (3.04e-3)" "unprognostic (4.37e-1)" "unprognostic (2.18e-2)" "unprognostic (1.06e-1)" "unprognostic (2.19e-1)" "unprognostic (1.24e-1)" "unprognostic (5.17e-2)" 4.4 11.1 2.3 1.2 14.0 6.0 4.0 1.6 2.9 9.7 0.3 3.1 5.2 3.8 1.3 0.9 2.8 7.2 2.2 1.0 4.6 8.9 2.0 5.9 0.5 7.0 9.3 0.5 1.9 6.6 3.5 6.9 5.9 7.0 3.3 16.7 2.0 2.3 1.9 1.8 6.7 2.0 2.6 5.4 1.9 6.3 4.3 3.5 0.2 1.2 0.4 2.0 2.7 2.4 0.0 0.0 14.2 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 22.5 0.0 0.0 0.0 16.8 0.2 0.0 0.0 0.4 37.9 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.9 16.7 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 36.9 29.5 0.0 0.0 0.0 0.1 0.9 26.9 0.0 0.4 0.3 0.0 0.8 0.0 0.0 0.0 1.0 0.0 0.2 4.2 0.1 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 4.2 0.0 6.4 0.0 0.1 2.3 14.0 1.6 2.9 1.0 4.6 7.0 9.3 5.9 2.6 4.3 2.4 36.4 0.0 0.6 15.7 0.5 1.7 3.6 0.0 0.0 15.4 19.4 9.3 2.1 1.5 0.0 7.3 4.2 0.0 12.5 0.9 5.9 1.0 88.5 5.0 4.7 34.2 34.1 2.5 77.0 0.0 0.0 4.6 1.1 3.2 5.1 0.3 2.9 0.0 0.2 87.5 28.2 21.4 0.0 1.2 1.2 103.7 3.4 2.5 0.0 143.4 1.1 143.8 0.0 6.6 3.9 0.6 0.3 1.9 0.0 5.8 3.5 6.9 0.7 6.9 13.1 1.5 4.3 58.8 10.2 0.2 1.3 0.0 1.0 1.3 12.6 2.7 DAW1 "FLJ25955, ODA16, WDR69" ENSG00000123977 "Dynein assembly factor with WD repeats 1" Q8N136 2 227871054-227924344 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "choroid plexus: 25.7;fallopian tube: 32.6;testis: 51.3" "Group enriched" "Detected in some" 13 "Early spermatids: 106.7;Late spermatids: 215.3;Respiratory ciliated cells: 113.9;Spermatocytes: 177.1" "Cancer enhanced" "Detected in some" "lung cancer: 0.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 8.8;HUVEC TERT2: 21.8;U-2197: 40.7" "Low region specificity" "Detected in many" HPA046118 Approved Approved "Nucleoplasm,Nuclear bodies,Plasma membrane" NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 18: U-2197 - ECM organization" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "Nuclear bodies, Plasma membrane" "HPA046118: AB_10961428" "unprognostic (1.23e-1)" "unprognostic (1.42e-1)" "unprognostic (1.95e-1)" "unprognostic (1.66e-1)" "unprognostic (4.37e-1)" "unprognostic (1.23e-1)" "unprognostic (5.63e-3)" "unprognostic (2.90e-2)" "unprognostic (9.92e-3)" "unprognostic (1.54e-5)" "unprognostic (1.52e-1)" "unprognostic (6.83e-3)" "unprognostic (1.70e-1)" "unprognostic (3.08e-1)" 0.6 0.0 4.3 0.1 5.3 0.3 0.4 2.9 4.7 0.7 25.7 0.2 0.0 0.1 0.3 0.5 32.6 0.3 0.5 4.5 4.5 0.2 0.4 3.0 0.2 7.3 8.8 0.1 0.0 0.2 0.2 0.8 5.5 0.0 0.0 0.7 0.1 0.0 3.6 0.2 0.0 0.1 6.8 0.2 0.1 51.3 5.4 0.4 0.1 0.0 0.2 0.1 0.0 5.4 0.8 0.0 0.1 0.0 0.3 1.2 0.6 0.8 0.4 0.9 0.6 5.4 0.5 0.2 0.0 0.2 8.8 0.1 0.0 0.2 2.1 0.0 0.0 0.0 0.4 0.0 1.1 0.0 0.1 1.7 0.0 1.0 0.7 5.8 21.8 0.0 0.0 0.3 0.4 0.0 0.0 0.5 0.5 0.0 0.2 0.0 0.1 0.3 0.1 0.2 0.4 0.1 0.8 0.0 0.0 0.2 0.0 0.5 2.2 0.2 2.0 40.7 0.0 0.0 0.1 0.3 3.9 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 5.3 2.9 4.7 4.5 4.5 7.3 8.8 5.5 6.8 5.4 5.4 0.0 0.0 1.1 0.3 0.0 0.0 0.0 9.6 0.0 0.0 0.0 0.0 0.7 0.0 11.5 0.0 4.2 0.2 0.0 0.0 0.0 0.2 106.7 11.2 0.0 0.2 0.0 0.0 6.2 0.0 2.8 1.7 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 8.2 0.0 0.0 215.3 3.4 0.3 0.0 0.0 0.0 0.2 0.0 0.5 0.1 3.0 0.2 2.6 0.0 0.1 0.0 0.1 113.9 0.3 0.0 0.7 2.1 177.1 4.1 0.0 0.1 0.3 0.0 0.0 0.1 0.0 DAZAP1 MGC19907 ENSG00000071626 "DAZ associated protein 1" Q96EP5 19 1407569-1435687 "Plasma proteins, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004201, HPA004631" Enhanced Enhanced Nucleoplasm,Cytosol NA NA 1600000 "Cluster 27: Non-specific - Gene expression" "Cluster 23: Testis - Cell cycle regulation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Cytosol "HPA004201: AB_1078627, HPA004631: AB_1078626" "unprognostic (1.50e-1)" "unprognostic (3.19e-2)" "unprognostic (7.69e-2)" "unprognostic (2.29e-1)" "unprognostic (7.31e-3)" "unprognostic (2.04e-1)" "prognostic unfavorable (5.86e-4)" "unprognostic (1.83e-1)" "unprognostic (2.30e-1)" "unprognostic (6.13e-2)" "unprognostic (1.09e-1)" "unprognostic (8.11e-3)" "unprognostic (2.72e-3)" "unprognostic (2.40e-3)" "unprognostic (8.30e-2)" "unprognostic (1.65e-1)" "unprognostic (2.21e-3)" 44.2 34.7 20.5 55.9 21.4 69.3 37.2 22.8 23.5 31.9 23.1 45.1 45.3 33.5 10.5 64.7 32.1 13.3 55.0 19.7 20.7 40.6 51.2 37.0 49.8 23.6 21.2 32.3 48.0 20.3 22.6 22.2 22.3 33.0 23.6 20.1 32.4 17.1 65.2 42.3 46.9 19.5 18.2 49.3 39.0 77.5 25.2 47.7 32.1 21.4 34.4 42.2 36.7 27.0 275.7 98.0 64.3 117.9 27.8 33.5 183.9 120.7 59.6 95.7 78.2 98.0 132.3 320.8 72.1 58.7 47.4 151.2 84.9 114.5 80.7 225.9 135.2 165.4 95.2 101.3 64.3 203.1 136.1 33.7 73.8 65.4 119.0 41.1 85.0 133.7 251.5 164.1 60.6 111.9 357.5 178.3 198.7 99.6 97.1 254.3 102.4 199.3 72.9 91.7 127.3 114.2 79.9 124.0 149.3 83.1 113.1 266.8 93.7 79.0 107.5 139.7 267.9 192.9 212.2 256.0 95.6 194.4 123.8 1.5 2.3 1.9 2.7 3.4 2.9 3.1 2.4 2.9 2.2 2.1 2.4 2.6 1.0 3.0 2.4 2.7 2.7 1.3 20.5 21.4 22.8 23.5 19.7 20.7 23.6 21.2 22.3 18.2 25.2 27.0 57.1 9.6 27.6 29.7 50.3 69.3 90.9 37.6 34.1 55.7 46.9 33.3 40.0 38.6 28.8 25.8 35.5 43.5 68.7 60.0 23.5 44.4 49.8 26.3 37.0 45.0 33.0 96.6 17.1 55.1 108.6 39.7 46.9 34.0 26.6 58.0 36.0 41.6 47.7 26.9 16.8 71.6 28.5 49.2 54.9 65.7 28.0 50.3 40.9 16.9 36.0 35.1 34.0 18.6 45.2 63.5 49.4 23.7 73.6 110.3 50.4 48.2 23.5 45.4 26.3 50.5 58.9 111.6 41.0 67.0 74.9 69.0 53.0 41.8 81.5 107.9 DBX2 FLJ16139 ENSG00000185610 "Developing brain homeobox 2" Q6ZNG2 12 45014672-45051099 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 12 "brain: 9.3" "Group enriched" "Detected in some" 9 "Astrocytes: 11.4;Oligodendrocyte precursor cells: 14.1;Spermatogonia: 5.1" "Cancer enriched" "Detected in single" 32 "glioma: 4.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065045, HPA066053" Uncertain Approved "Nucleoplasm,Nuclear membrane,Vesicles" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" "Nucleoplasm, Nuclear membrane" Vesicles "HPA065045: , HPA066053: AB_2685605" "unprognostic (1.13e-4)" "unprognostic (9.99e-2)" "unprognostic (7.82e-3)" "unprognostic (5.24e-2)" "unprognostic (5.62e-2)" "unprognostic (1.51e-1)" "unprognostic (9.22e-2)" "unprognostic (4.76e-2)" "unprognostic (1.64e-1)" "unprognostic (5.19e-1)" 0.4 0.0 3.6 0.0 4.0 0.0 0.2 3.7 3.7 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.4 3.6 0.1 0.0 0.0 0.0 8.2 4.6 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 9.3 0.0 0.0 0.6 5.2 0.0 0.2 0.2 0.0 0.0 0.1 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 4.0 3.7 3.7 3.4 3.6 8.2 4.6 5.6 9.3 5.2 7.4 0.0 0.0 0.0 11.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 5.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 DCAF1 "KIAA0800, MGC102804, VPRBP" ENSG00000145041 "DDB1 and CUL4 associated factor 1" Q9Y4B6 3 51395867-51500002 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation, Ubl conjugation pathway" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 53.4" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 17.9;Granulosa cells: 13.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036142, HPA052445, HPA053203" Approved Supported "Nucleoplasm,Nucleoli fibrillar center" No No "Cluster 27: Non-specific - Gene expression" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Nucleoli fibrillar center" "HPA036142: AB_10669666, HPA052445: AB_2681835, HPA053203: AB_2682080" "unprognostic (7.51e-2)" "unprognostic (3.19e-1)" "unprognostic (3.71e-3)" "unprognostic (1.26e-1)" "unprognostic (5.15e-2)" "unprognostic (9.75e-2)" "unprognostic (2.58e-2)" "unprognostic (1.24e-1)" "unprognostic (8.75e-2)" "unprognostic (2.15e-1)" "unprognostic (2.89e-2)" "unprognostic (2.21e-2)" "prognostic favorable (7.45e-5)" "unprognostic (5.49e-2)" "unprognostic (5.00e-1)" "unprognostic (6.81e-2)" "unprognostic (1.64e-1)" 11.4 11.3 7.6 11.7 8.8 15.9 11.2 11.2 9.4 9.4 9.8 11.0 7.9 10.3 9.4 10.6 8.9 7.4 9.5 7.8 9.3 11.0 11.5 10.0 14.8 8.4 8.8 10.3 10.4 18.9 8.6 10.3 8.6 9.7 10.9 19.7 11.3 9.6 27.9 13.5 11.4 9.2 8.0 11.3 10.3 53.4 8.5 18.6 14.6 16.1 15.9 11.2 10.0 9.0 19.9 23.9 22.8 20.7 20.1 15.9 21.6 21.8 16.2 23.1 22.5 26.4 18.8 48.1 11.7 17.2 35.3 17.1 43.3 19.5 29.6 33.7 21.5 41.2 32.4 22.8 14.7 54.4 28.7 10.6 22.2 29.8 21.6 15.0 18.2 26.1 24.5 30.3 18.3 20.3 41.8 22.0 24.0 23.5 26.0 17.5 24.4 32.0 18.0 30.5 11.8 21.0 24.1 22.0 13.2 16.7 15.0 22.8 22.9 18.8 25.1 31.4 33.9 20.5 29.7 48.2 21.9 36.6 15.7 2.5 3.0 2.4 6.5 3.3 7.4 5.1 5.6 5.6 4.8 4.9 6.0 5.1 0.7 5.8 5.0 3.8 6.7 4.9 7.6 8.8 11.2 9.4 7.8 9.3 8.4 8.8 8.6 8.0 8.5 9.0 11.1 3.2 10.6 0.0 3.6 0.0 0.0 0.0 0.0 0.0 11.3 9.4 0.0 0.0 6.8 3.7 0.0 7.6 9.7 0.0 1.9 7.0 0.0 11.2 10.3 5.6 0.0 0.0 0.0 6.7 5.7 3.0 0.0 17.9 6.3 13.1 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 2.6 0.0 0.0 0.0 0.0 7.5 0.0 0.0 2.8 0.0 0.0 6.1 5.1 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 10.5 5.0 7.4 0.0 0.0 DCAF15 "C19orf72, MGC99481" ENSG00000132017 "DDB1 and CUL4 associated factor 15" Q66K64 19 13952492-13961449 "Predicted intracellular proteins" "Immunity, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068351 Approved Vesicles,Mitochondria NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 12: NES - Nervous system development" "Cluster 7: Non-specific - Mitochondria" Mitochondria Vesicles "HPA068351: AB_2685977" "unprognostic (6.91e-2)" "unprognostic (6.55e-3)" "unprognostic (3.03e-2)" "unprognostic (5.18e-3)" "unprognostic (1.95e-1)" "unprognostic (1.89e-2)" "unprognostic (1.83e-3)" "unprognostic (9.72e-2)" "unprognostic (8.03e-2)" "unprognostic (1.21e-1)" "prognostic favorable (7.97e-4)" "unprognostic (1.98e-2)" "prognostic unfavorable (1.34e-5)" "unprognostic (7.97e-3)" "unprognostic (1.26e-1)" "unprognostic (1.07e-1)" "unprognostic (1.59e-1)" 17.6 10.7 5.9 10.3 6.0 20.5 18.1 7.1 7.9 18.7 4.7 18.1 6.9 17.0 4.3 24.0 16.7 4.5 18.6 6.0 5.6 16.2 13.9 18.6 13.5 5.6 5.2 15.5 13.7 7.1 16.5 7.3 5.2 17.0 5.2 3.6 16.1 5.3 22.9 30.2 23.4 5.1 4.9 33.4 14.0 44.7 5.6 14.6 17.0 8.6 10.8 15.6 21.6 5.4 18.9 11.5 29.5 16.2 3.1 4.5 13.5 12.7 8.8 26.1 25.9 20.4 7.9 17.3 14.4 12.3 15.4 16.7 18.9 12.0 9.2 21.0 33.8 21.3 21.0 21.4 6.5 17.8 30.2 5.9 10.9 19.3 8.6 9.4 13.1 27.4 22.9 24.8 11.6 28.7 32.0 33.0 35.2 12.7 17.8 29.2 10.4 11.8 14.1 14.3 18.8 19.3 11.4 8.1 10.7 12.1 10.5 22.7 9.2 17.8 13.1 28.3 24.1 17.4 20.7 18.3 11.4 25.8 15.6 0.2 0.3 0.9 0.3 0.3 0.2 0.3 0.2 0.3 0.2 0.4 0.1 0.3 0.6 0.1 0.2 0.4 0.6 0.2 5.9 6.0 7.1 7.9 6.0 5.6 5.6 5.2 5.2 4.9 5.6 5.4 19.5 0.0 0.0 6.8 19.7 4.8 10.5 6.9 8.6 17.3 8.9 10.7 2.9 10.0 3.8 9.2 8.4 13.7 24.4 9.6 1.9 11.0 5.0 7.0 7.8 10.9 7.7 9.4 5.2 10.3 15.1 7.5 13.7 7.0 1.3 15.0 7.1 3.4 15.7 15.2 3.4 5.7 4.1 8.1 7.0 9.5 18.3 14.3 1.8 8.4 13.8 9.2 16.5 7.1 5.5 9.9 9.6 12.0 18.3 6.4 4.5 4.7 3.9 13.9 6.6 6.0 7.9 35.6 19.9 10.0 9.8 13.8 21.2 10.4 7.9 8.9 DCBLD2 "CLCP1, ESDN" ENSG00000057019 "Discoidin, CUB and LCCL domain containing 2" Q96PD2 3 98795941-98901695 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 83.8;Oligodendrocyte precursor cells: 88.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-HME1: 455.0;hTERT-RPE1: 648.9;LHCN-M2: 776.8;RPTEC TERT1: 479.0;U-87 MG: 581.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016909 Approved Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA 2200000 "Cluster 21: Non-specific - Transcription" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane, Cytosol" "Golgi apparatus" "HPA016909: AB_1847510" "unprognostic (1.66e-1)" "unprognostic (1.45e-1)" "unprognostic (4.46e-2)" "unprognostic (2.64e-1)" "unprognostic (5.97e-3)" "unprognostic (9.29e-3)" "unprognostic (8.31e-3)" "unprognostic (1.06e-3)" "unprognostic (1.42e-1)" "unprognostic (1.63e-1)" "prognostic unfavorable (1.52e-4)" "unprognostic (2.43e-1)" "prognostic unfavorable (3.32e-5)" "prognostic unfavorable (2.87e-4)" "unprognostic (7.76e-2)" "unprognostic (3.93e-2)" "unprognostic (1.59e-3)" 12.2 13.3 4.0 4.5 3.8 1.2 8.2 8.1 5.8 8.3 6.6 11.5 2.8 14.6 8.0 6.4 14.5 12.5 27.6 3.4 5.9 11.0 9.8 11.5 3.6 6.5 6.9 17.8 5.8 13.2 6.6 8.0 26.7 11.5 7.0 22.4 10.1 14.9 5.2 8.3 4.1 16.3 4.8 1.6 6.5 23.8 7.3 6.9 15.7 8.4 3.9 7.8 5.1 5.0 55.3 397.0 52.3 41.2 67.8 160.1 22.7 122.0 57.9 81.4 91.9 33.9 171.6 0.1 373.7 211.5 249.0 50.3 24.1 198.8 186.2 0.8 8.4 19.4 12.1 51.5 41.6 9.3 8.7 63.8 30.3 234.3 455.0 648.9 54.6 7.1 4.0 5.0 776.8 14.6 7.7 5.5 36.5 0.4 135.6 8.1 98.2 4.8 479.0 14.4 14.0 24.3 33.5 6.9 145.9 35.2 26.4 7.3 90.4 208.0 166.6 53.8 433.0 6.3 9.7 7.4 581.3 3.4 92.8 0.2 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 4.0 3.8 8.1 5.8 3.4 5.9 6.5 6.9 26.7 4.8 7.3 5.0 5.9 32.1 52.8 18.3 2.7 22.8 15.5 18.2 17.1 12.9 15.5 16.3 83.8 17.2 19.0 18.4 77.2 12.4 1.6 4.3 0.0 30.5 3.1 32.2 39.5 7.7 3.6 5.9 51.6 8.0 9.7 33.8 6.1 38.3 38.0 52.2 6.8 20.5 4.0 13.5 51.3 8.0 20.3 3.2 6.2 5.8 22.1 4.0 8.8 25.3 1.4 40.9 2.1 88.4 38.9 26.3 4.6 50.4 1.6 11.9 0.7 7.9 22.8 48.9 0.0 12.3 31.3 15.8 24.2 14.1 15.6 4.0 1.8 34.4 8.2 7.1 DCDC2 "DCDC2A, DFNB66, KIAA1154, NPHP19, RU2" ENSG00000146038 "Doublecortin domain containing 2" Q9UHG0 6 24171755-24358059 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation, Neurogenesis" "Ciliopathy, Deafness, Disease variant, Nephronophthisis, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 15.1;kidney: 23.2;pancreas: 26.2" "Cell type enhanced" "Detected in many" "Cholangiocytes: 62.9;Collecting duct cells: 79.1;Distal tubular cells: 56.7;Ductal cells: 135.9;Endometrial ciliated cells: 160.3;Glandular and luminal cells: 102.4;Proximal tubular cells: 54.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 71.8;EFO-21: 48.3;Hep G2: 82.3;RPTEC TERT1: 254.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA031582, HPA031583, HPA031584" Enhanced Supported "Microtubules,Mitotic spindle,Centriolar satellite,Cytosol" Yes NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" Cytosol "Microtubules, Mitotic spindle, Centriolar satellite" "HPA031582: AB_10600901, HPA031583: AB_2673944, HPA031584: AB_2673945" "unprognostic (8.65e-2)" "unprognostic (2.07e-2)" "unprognostic (1.66e-1)" "unprognostic (6.70e-2)" "unprognostic (1.08e-2)" "unprognostic (3.22e-1)" "unprognostic (1.03e-1)" "unprognostic (1.45e-1)" "unprognostic (2.90e-1)" "unprognostic (7.87e-2)" "unprognostic (1.81e-1)" "unprognostic (1.09e-1)" "unprognostic (2.67e-2)" "unprognostic (5.22e-2)" "unprognostic (1.16e-1)" "unprognostic (2.12e-2)" "unprognostic (2.99e-2)" 0.0 1.3 0.8 0.0 1.2 0.1 4.4 0.3 0.8 1.6 15.1 0.7 0.6 4.4 5.3 0.0 7.6 3.9 0.0 0.8 1.0 23.2 2.2 3.4 0.0 2.2 2.7 0.2 26.2 8.2 1.2 0.6 1.7 1.2 0.6 1.4 0.4 2.3 0.3 0.1 0.1 0.1 2.0 0.1 1.8 3.7 1.1 0.1 8.2 0.2 0.0 0.4 0.0 1.6 0.0 8.8 0.5 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.0 71.8 0.2 0.0 48.3 0.0 0.1 0.0 0.0 0.1 0.1 0.0 8.2 0.0 0.0 82.3 0.0 0.0 0.0 0.0 0.0 9.7 0.0 1.4 0.0 0.2 0.1 0.0 0.3 10.8 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 254.5 0.3 5.2 0.5 0.0 1.3 0.0 0.2 12.3 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.5 0.5 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.8 1.2 0.3 0.8 0.8 1.0 2.2 2.7 1.7 2.0 1.1 1.6 0.2 19.2 14.4 3.9 1.4 0.1 0.6 0.3 0.0 0.0 20.3 11.7 0.3 62.9 6.1 79.1 0.0 0.4 0.0 1.2 56.7 135.9 40.1 160.3 5.3 0.4 3.6 0.0 11.3 8.4 0.0 1.3 3.6 102.4 0.0 4.1 0.0 1.0 0.5 0.0 8.3 2.9 0.0 0.0 0.0 14.6 0.3 1.0 0.0 1.0 2.0 2.3 0.0 1.0 0.5 27.9 4.1 0.4 0.0 1.3 0.0 54.3 37.1 0.1 0.0 0.0 2.4 32.3 2.6 0.0 0.1 0.1 1.1 5.6 2.7 0.9 DCDC2C ENSG00000214866 "Doublecortin domain containing 2C" A8MYV0 2 3703575-3848008 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 4.1" "Group enriched" "Detected in some" 7 "Early spermatids: 171.3;Late spermatids: 59.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Karpas-707: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA045848 Uncertain NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 29: Early spermatids - Spermatogenesis" "HPA045848: AB_10961120" "unprognostic (2.63e-2)" "unprognostic (1.81e-1)" "unprognostic (3.81e-3)" "unprognostic (6.98e-2)" 0.1 0.0 0.6 0.0 0.5 0.4 0.1 0.9 0.9 0.0 1.2 0.0 0.0 0.1 0.4 0.1 0.1 0.0 0.0 0.5 0.5 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.2 0.1 0.1 0.4 0.0 0.1 0.2 0.2 0.1 0.0 0.0 0.0 0.2 4.1 0.6 0.2 0.1 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 1.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.5 0.9 0.9 0.5 0.5 0.1 0.1 0.2 0.0 0.6 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 171.3 0.0 0.4 2.3 0.0 0.0 0.6 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 59.9 5.6 0.1 0.0 15.9 0.0 0.0 0.0 0.0 0.2 0.3 0.0 11.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 1.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 DCTN5 "MGC3248, p25" ENSG00000166847 "Dynactin subunit 5" Q9BTE1 16 23641466-23677472 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042003, HPA063710" Approved Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Nuclear membrane" "HPA042003: AB_10796468, HPA063710: AB_2685101" "unprognostic (5.90e-3)" "unprognostic (3.38e-1)" "unprognostic (1.77e-1)" "unprognostic (2.61e-2)" "unprognostic (3.22e-2)" "unprognostic (1.28e-2)" "prognostic unfavorable (4.02e-4)" "unprognostic (1.18e-1)" "unprognostic (1.25e-1)" "unprognostic (6.36e-2)" "unprognostic (6.78e-2)" "unprognostic (9.28e-2)" "prognostic favorable (4.48e-4)" "unprognostic (1.17e-1)" "unprognostic (1.61e-1)" "unprognostic (1.59e-2)" "unprognostic (9.55e-2)" 13.9 11.3 14.6 18.1 18.1 41.5 14.2 10.4 18.3 13.6 3.8 19.2 20.8 14.8 12.0 25.2 13.6 14.2 14.7 17.2 13.0 21.0 10.7 14.0 22.1 11.4 13.6 12.0 15.9 19.8 8.5 20.9 11.1 14.1 24.9 21.5 12.8 14.0 13.9 14.1 22.2 21.7 11.4 15.1 16.7 20.6 12.8 20.9 18.8 14.2 32.2 20.6 10.9 12.9 30.0 58.5 56.0 46.9 39.0 28.9 39.2 51.9 32.1 32.9 39.3 66.5 40.3 42.1 41.2 54.8 34.6 30.6 93.4 50.2 40.5 48.1 37.1 51.9 67.2 93.9 26.5 63.7 38.4 24.3 35.3 40.5 42.8 36.5 52.8 52.0 100.7 31.6 53.3 82.4 49.4 18.4 66.3 43.3 25.5 59.8 48.6 45.9 26.2 62.6 46.8 48.5 45.6 36.7 30.5 49.0 51.2 53.2 71.8 44.0 20.0 34.9 36.6 42.6 68.6 66.2 42.0 31.4 48.8 14.3 16.6 20.3 15.5 14.0 17.1 13.9 14.2 17.0 17.5 10.5 12.0 14.3 7.3 22.0 22.0 12.4 19.0 17.2 14.6 18.1 10.4 18.3 17.2 13.0 11.4 13.6 11.1 11.4 12.8 12.9 19.7 16.0 26.2 12.1 19.1 14.7 14.5 12.9 22.8 52.1 15.5 14.5 27.1 15.7 15.6 20.2 91.8 32.9 16.1 36.2 11.7 23.8 23.2 11.9 22.4 22.5 22.1 27.6 13.4 25.2 36.3 16.3 20.9 20.8 27.8 37.3 17.2 14.2 28.4 52.2 13.2 18.9 12.2 19.1 11.4 23.4 13.1 17.1 7.2 6.5 34.4 32.3 30.9 11.1 12.0 45.7 19.4 18.0 17.4 14.4 31.9 23.3 11.2 45.0 13.1 22.4 18.1 70.4 30.6 20.9 14.2 48.2 18.7 17.9 26.2 22.0 DCUN1D2 "C13orf17, FLJ10704, FLJ20092" ENSG00000150401 "Defective in cullin neddylation 1 domain containing 2" Q6PH85 13 113455819-113490951 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 98.6;skeletal muscle: 108.7;tongue: 69.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 79.6;Excitatory neurons: 43.9;Inhibitory neurons: 37.9;Oligodendrocytes: 42.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 11.3" "Lineage enriched" "Detected in all" 4 "granulocytes: 11.3" "Cell line enhanced" "Detected in all" "SCLC-21H: 54.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039349 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane, Cytosol" "HPA039349: AB_10673240" "unprognostic (3.09e-1)" "unprognostic (1.35e-1)" "unprognostic (1.78e-1)" "unprognostic (4.69e-2)" "unprognostic (7.43e-2)" "unprognostic (7.68e-2)" "unprognostic (4.33e-2)" "unprognostic (1.15e-1)" "unprognostic (1.40e-1)" "unprognostic (2.02e-2)" "prognostic favorable (5.65e-5)" "unprognostic (1.21e-2)" "unprognostic (7.20e-2)" "unprognostic (3.57e-2)" "unprognostic (1.28e-1)" "unprognostic (3.69e-2)" "unprognostic (1.25e-2)" 8.1 8.4 9.7 4.4 8.8 14.0 7.6 23.4 14.6 8.9 30.1 9.2 4.6 9.4 9.4 6.4 7.7 5.4 98.6 8.5 9.7 8.3 8.5 7.7 7.2 12.6 9.9 8.1 7.1 5.9 10.5 7.4 13.4 7.5 6.4 16.8 9.0 4.8 108.7 14.4 8.3 7.4 8.5 9.4 8.3 9.0 10.2 8.1 4.5 69.1 7.3 7.0 7.4 15.3 13.3 7.5 13.0 9.5 9.8 8.3 10.6 10.0 11.4 9.0 10.8 27.4 7.3 9.8 3.4 11.3 13.9 17.2 13.8 7.1 12.5 6.7 23.4 15.6 40.9 7.5 6.0 24.5 11.2 12.0 11.6 9.8 9.0 6.2 8.3 12.9 9.2 8.4 8.6 9.0 16.6 38.1 8.9 9.7 11.8 16.9 20.8 11.2 6.4 8.3 54.7 12.2 6.9 24.6 7.0 8.8 14.1 10.6 12.7 11.3 16.4 9.0 14.3 25.5 11.4 19.2 25.3 10.4 7.7 11.3 1.5 2.2 2.0 1.0 2.5 1.9 1.8 1.4 1.6 0.9 1.8 0.9 0.8 1.9 1.5 0.2 2.0 1.5 9.7 8.8 23.4 14.6 8.5 9.7 12.6 9.9 13.4 8.5 10.2 15.3 7.6 16.0 15.6 27.4 2.4 5.9 2.0 2.3 1.8 9.0 6.7 4.3 79.6 0.0 8.4 3.7 16.7 2.4 2.5 4.8 1.9 1.7 5.9 5.0 6.5 7.1 6.6 3.0 43.9 1.3 1.4 6.6 8.2 6.0 5.1 4.6 5.7 3.9 1.4 18.5 37.9 4.4 0.0 3.5 4.4 8.3 7.2 4.2 5.4 18.7 2.2 4.8 3.1 30.2 42.8 2.1 1.3 5.7 2.0 3.7 3.4 2.5 4.6 9.6 0.0 3.5 3.7 3.8 4.2 4.3 7.4 2.6 3.5 5.2 3.9 3.2 DDIAS "C11orf82, FLJ25416, FLJ38838, noxin" ENSG00000165490 "DNA damage induced apoptosis suppressor" Q8IXT1 11 82899975-82958277 "Predicted intracellular proteins" "Apoptosis, Cell cycle, Growth arrest" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 7.9;testis: 10.8" "Cell type enhanced" "Detected in many" "Plasma cells: 8.2;Spermatocytes: 17.2;Spermatogonia: 18.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA038540, HPA038541" Approved Approved "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Cytosol" "HPA038540: AB_10672648, HPA038541: AB_2676071" "unprognostic (2.53e-1)" "unprognostic (2.27e-1)" "unprognostic (5.04e-3)" "unprognostic (1.25e-2)" "unprognostic (1.20e-1)" "unprognostic (5.32e-2)" "unprognostic (3.86e-6)" "unprognostic (4.65e-3)" "unprognostic (1.01e-3)" "unprognostic (8.24e-3)" "unprognostic (2.04e-4)" "unprognostic (4.72e-2)" "unprognostic (1.11e-16)" "unprognostic (7.17e-3)" "unprognostic (9.59e-2)" "unprognostic (1.89e-1)" "unprognostic (9.13e-2)" 0.9 0.4 0.6 3.3 0.9 7.9 2.1 0.9 1.0 0.7 0.4 1.8 1.6 1.2 1.0 2.9 0.5 0.7 0.5 0.8 0.4 0.4 1.2 3.4 4.4 0.8 0.8 0.5 0.9 0.1 0.1 1.9 0.7 0.5 2.2 0.5 0.8 0.4 1.0 2.2 1.5 1.8 0.5 2.9 0.9 10.8 0.8 5.3 0.4 0.9 6.2 3.5 0.9 1.8 13.6 22.6 21.0 15.2 1.9 3.1 15.3 25.4 10.5 26.8 31.0 22.4 16.2 16.1 36.1 5.7 21.6 24.7 36.0 15.5 36.8 30.7 19.7 23.1 10.6 9.1 0.2 28.6 19.7 0.7 1.4 33.8 15.6 2.3 12.8 20.5 23.9 27.0 23.9 19.6 27.0 23.2 25.1 36.5 24.4 20.0 40.5 20.6 5.7 23.3 15.6 21.5 15.2 15.6 5.7 20.2 16.5 11.7 6.0 26.7 35.9 71.1 30.4 15.4 44.3 56.4 8.4 20.2 26.3 0.7 10.3 4.1 0.5 7.9 0.2 1.1 0.3 0.7 4.5 1.7 0.6 0.4 5.5 2.2 8.5 1.4 0.5 3.2 0.6 0.9 0.9 1.0 0.8 0.4 0.8 0.8 0.7 0.5 0.8 1.8 0.3 0.0 0.0 0.0 4.3 0.0 0.6 0.0 1.8 0.0 1.1 1.1 0.9 1.5 0.0 0.0 0.0 2.7 1.0 0.6 0.0 0.9 4.2 1.0 0.6 0.8 0.0 6.5 0.6 0.6 5.5 0.8 1.1 1.2 0.0 2.5 0.7 0.7 2.5 0.0 0.3 0.7 0.0 6.4 0.0 1.9 0.3 3.5 0.0 1.9 4.5 0.0 4.1 0.5 0.6 0.5 0.1 0.7 8.2 0.7 0.3 0.3 0.0 0.0 0.0 0.8 1.1 17.2 18.2 5.4 0.0 0.3 1.5 0.5 1.6 0.9 DDX25 GRTH ENSG00000109832 "DEAD-box helicase 25" Q9UHL0 11 125903348-125943702 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Differentiation, mRNA transport, Spermatogenesis, Translation regulation, Transport" "Developmental protein, Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "testis: 91.4" "Group enriched" "Detected in some" 4 "Early spermatids: 332.1;Spermatocytes: 266.3" "Cancer enhanced" "Detected in some" "glioma: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "JURKAT: 16.1;NTERA-2: 10.8;SCLC-21H: 8.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020137 Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 11: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm Cytosol "HPA020137: AB_1847552" "unprognostic (5.78e-3)" "unprognostic (9.75e-3)" "unprognostic (7.93e-2)" "unprognostic (5.09e-3)" "unprognostic (1.11e-2)" "unprognostic (1.78e-2)" "unprognostic (1.54e-1)" "unprognostic (2.91e-3)" "unprognostic (6.24e-5)" "unprognostic (2.57e-1)" "unprognostic (2.44e-3)" "unprognostic (3.89e-1)" "unprognostic (3.44e-3)" "unprognostic (1.44e-1)" "unprognostic (1.76e-1)" "unprognostic (9.72e-2)" "unprognostic (1.69e-1)" 0.4 2.7 15.0 0.1 16.1 0.3 0.3 12.4 17.0 0.3 4.0 0.4 0.4 0.3 0.2 0.1 0.6 0.1 0.0 14.3 16.7 2.6 0.3 0.2 0.1 8.7 10.4 0.6 1.4 1.7 14.9 0.2 10.6 0.2 0.1 21.8 0.2 0.4 0.1 1.1 0.1 0.0 7.6 0.3 0.4 91.4 15.0 0.6 4.7 0.1 0.1 0.0 0.2 13.5 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.2 0.1 1.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 16.1 0.0 0.2 0.0 0.5 1.7 0.0 10.8 0.5 0.0 0.4 0.0 0.0 0.0 0.1 8.7 1.9 0.1 0.0 1.7 1.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.6 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.4 0.2 0.0 0.1 0.0 0.0 15.0 16.1 12.4 17.0 14.3 16.7 8.7 10.4 10.6 7.6 15.0 13.5 0.2 0.0 0.5 16.0 0.5 0.1 0.8 0.0 2.2 18.0 0.1 0.8 1.1 0.0 0.0 0.0 16.7 0.1 0.0 0.0 3.9 0.3 332.1 0.2 0.0 1.0 0.0 0.0 18.0 0.2 0.2 0.4 0.0 0.1 0.0 2.3 0.4 0.5 0.1 16.8 23.1 0.0 0.0 0.0 0.3 66.0 3.7 0.4 0.0 1.9 0.0 20.2 0.0 15.6 3.1 0.1 0.0 4.9 0.0 0.5 0.0 2.7 0.0 16.6 0.0 0.2 0.3 266.3 28.6 0.4 0.0 0.0 0.1 4.0 0.0 0.2 DECR2 "PDCR, SDR17C1" ENSG00000242612 "2,4-dienoyl-CoA reductase 2" Q9NUI1 16 401858-412487 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 165.1" "Cell type enhanced" "Detected in many" "Hepatocytes: 129.2;Proximal enterocytes: 81.3;Proximal tubular cells: 159.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Hep G2: 37.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047631 Approved Peroxisomes,Microtubules NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Peroxisomes Microtubules "HPA047631: " "unprognostic (2.74e-2)" "unprognostic (3.84e-1)" "unprognostic (1.83e-1)" "unprognostic (4.44e-3)" "unprognostic (1.77e-1)" "unprognostic (7.45e-2)" "unprognostic (2.38e-2)" "unprognostic (1.17e-1)" "unprognostic (1.91e-1)" "unprognostic (3.02e-2)" "unprognostic (3.11e-2)" "unprognostic (3.38e-1)" "unprognostic (1.12e-1)" "unprognostic (3.40e-1)" "unprognostic (2.21e-1)" "unprognostic (1.94e-1)" "unprognostic (4.22e-3)" 13.0 34.8 5.5 1.6 5.7 5.8 11.8 5.5 8.1 9.6 5.4 18.5 20.6 10.0 2.0 12.0 9.2 2.1 12.4 6.0 6.6 35.8 165.1 6.8 1.2 5.6 5.5 8.6 21.2 1.7 8.4 2.4 5.5 11.9 2.8 0.5 9.5 7.1 32.3 10.5 17.4 1.5 5.5 6.8 13.8 11.4 6.1 1.8 6.3 7.2 1.0 10.7 8.1 6.1 2.4 22.5 3.4 14.7 4.1 6.3 7.7 7.0 5.7 6.0 6.7 16.2 16.2 6.1 12.2 7.5 3.7 3.5 2.1 6.4 1.3 12.4 5.7 2.3 10.3 37.6 17.7 4.9 11.1 9.1 4.8 4.2 5.5 6.1 6.9 9.5 4.3 7.9 5.5 27.7 3.2 10.2 8.0 9.0 7.5 5.8 1.3 12.2 6.9 6.3 4.3 8.5 11.3 15.9 8.8 1.3 21.9 10.1 10.8 5.1 5.8 7.5 5.6 6.7 7.1 2.6 7.0 10.2 16.1 0.0 3.8 0.1 2.7 5.1 1.5 1.8 1.1 1.5 5.1 1.7 2.6 1.5 0.2 2.9 2.5 7.8 0.9 2.6 5.5 5.7 5.5 8.1 6.0 6.6 5.6 5.5 5.5 5.5 6.1 6.1 9.6 12.8 16.2 5.2 4.3 3.8 7.3 5.6 10.2 2.0 14.9 15.6 8.3 20.0 7.4 20.2 0.0 34.3 5.7 53.8 39.2 37.3 2.6 7.1 8.1 9.4 12.5 29.5 2.3 38.9 7.1 9.9 38.7 9.6 12.7 15.8 7.5 129.2 12.9 3.3 2.7 30.6 6.1 7.3 5.7 6.3 6.5 6.0 5.4 0.0 10.0 7.0 5.2 3.0 2.8 25.3 37.2 6.8 3.8 6.4 81.3 159.1 7.7 3.0 0.0 7.7 8.3 3.8 6.3 12.6 6.0 12.6 3.5 25.8 38.8 5.1 DEFB119 "DEFB-19, DEFB-20, DEFB120" ENSG00000180483 "Defensin beta 119" Q8N690 20 31377164-31390590 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "epididymis: 1925.5" "Cell type enhanced" "Detected in some" "Bipolar cells: 42.6;Cone photoreceptor cells: 39.6;Early spermatids: 61.9;Late spermatids: 99.8;Rod photoreceptor cells: 150.2" "Cancer enriched" "Detected in single" 67 "testis cancer: 3.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "NB-4: 1.5" HPA043059 Supported "Secreted in male reproductive system" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA043059: AB_10797025" "unprognostic (2.03e-1)" 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.4 0.1 1925.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 155.7 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 331.5 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 42.6 0.0 0.0 0.0 0.0 0.0 0.0 39.6 0.0 0.0 0.0 0.0 0.0 61.9 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.1 0.1 0.0 0.0 0.0 0.0 99.8 12.5 0.8 0.0 0.0 0.0 22.0 0.0 0.0 0.1 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 150.2 13.1 0.0 0.0 17.4 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DENND3 KIAA0870 ENSG00000105339 "DENN domain containing 3" A2RUS2 8 141117278-141195808 "Predicted intracellular proteins, Predicted membrane proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 106.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 157.0;Microglial cells: 79.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 34.6;neutrophil: 39.8" "Group enriched" "Detected in many" 5 "granulocytes: 39.8;monocytes: 10.0" "Cell line enhanced" "Detected in many" "HDLM-2: 64.6;HeLa: 89.5;U-937: 58.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA024491, HPA041668" Approved Approved Vesicles,Cytosol NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 20: HeLa - Mitochondria" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Vesicles, Cytosol" "HPA024491: AB_2671581, HPA041668: " "unprognostic (2.27e-1)" "unprognostic (9.62e-2)" "unprognostic (9.47e-3)" "unprognostic (1.66e-1)" "unprognostic (6.96e-2)" "unprognostic (1.13e-1)" "unprognostic (1.53e-1)" "unprognostic (2.05e-1)" "unprognostic (1.55e-1)" "unprognostic (7.07e-3)" "unprognostic (2.71e-2)" "unprognostic (2.25e-2)" "unprognostic (7.74e-2)" "unprognostic (1.95e-1)" "unprognostic (2.02e-1)" "unprognostic (4.51e-2)" "unprognostic (5.42e-2)" 42.8 8.9 21.7 27.2 18.8 106.4 28.2 12.2 28.4 22.9 14.7 36.2 5.7 17.8 2.1 7.5 19.1 13.6 24.9 19.9 17.7 21.5 6.5 57.9 28.6 33.6 24.7 15.1 7.6 4.1 10.0 15.1 25.7 16.9 7.8 3.7 18.2 8.5 13.8 15.6 23.7 8.3 22.7 43.9 15.8 6.1 21.2 7.1 20.6 11.7 25.1 12.4 17.6 31.4 16.4 14.8 1.0 3.1 4.4 6.4 2.4 8.5 27.4 3.8 3.0 4.6 15.3 4.2 22.8 17.5 7.5 7.8 4.2 10.0 2.7 64.6 3.6 17.3 89.5 1.4 3.9 17.2 2.4 0.5 5.1 4.2 5.3 9.2 21.1 7.8 0.2 40.7 2.9 5.2 2.6 24.1 1.1 3.2 16.6 2.9 0.8 16.6 14.8 5.6 4.7 3.0 1.8 1.3 1.1 7.3 6.8 27.6 16.7 0.7 6.8 10.6 0.3 8.0 37.0 1.3 2.6 58.6 1.0 24.3 5.4 34.6 0.8 8.0 0.8 5.0 0.6 0.3 4.1 4.3 0.1 0.2 39.8 2.7 10.0 0.1 0.2 3.5 21.7 18.8 12.2 28.4 19.9 17.7 33.6 24.7 25.7 22.7 21.2 31.4 49.0 157.0 35.2 2.6 39.7 15.7 7.6 11.7 7.4 4.5 6.3 2.0 10.1 10.0 18.8 22.0 4.2 0.7 29.5 18.3 1.9 3.5 6.1 15.1 8.1 31.7 4.8 5.7 53.9 3.5 0.6 4.8 16.8 14.5 10.8 1.9 16.4 0.3 24.4 1.7 5.2 7.9 4.1 55.6 22.2 2.8 1.5 39.7 8.8 79.6 33.0 0.7 21.6 1.5 1.1 11.0 9.9 0.7 38.8 20.3 1.5 2.7 15.1 0.5 39.5 2.1 21.5 8.7 8.5 2.9 9.1 0.5 12.5 0.6 4.1 6.3 DEPDC4 "DEP.4, FLJ33505" ENSG00000166153 "DEP domain containing 4" Q8N2C3 12 100203669-100267079 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "testis: 3.9" "Cell type enhanced" "Detected in many" "Early spermatids: 13.7;Late spermatids: 19.2" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.1" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA039323 Uncertain Approved Microtubules NA NA "Cluster 24: B-cells - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Microtubules "HPA039323: AB_10674283" "unprognostic (8.89e-2)" "unprognostic (2.29e-1)" "unprognostic (1.09e-1)" "unprognostic (4.33e-2)" "unprognostic (3.62e-1)" "unprognostic (7.96e-2)" "unprognostic (1.59e-1)" "unprognostic (1.53e-1)" "unprognostic (9.09e-4)" "unprognostic (5.02e-2)" "unprognostic (1.05e-2)" "unprognostic (3.35e-1)" "unprognostic (1.04e-2)" "unprognostic (2.49e-1)" "unprognostic (1.87e-1)" "unprognostic (1.48e-1)" "unprognostic (1.37e-2)" 0.2 0.3 0.2 0.3 0.2 0.6 0.8 0.2 0.6 0.3 0.0 0.6 1.2 0.4 0.5 0.7 0.4 0.4 0.3 0.2 0.6 1.7 1.3 0.3 0.3 0.3 0.2 0.7 0.7 0.5 0.5 0.7 0.2 0.7 0.8 0.4 0.7 1.0 0.2 0.4 0.5 0.2 0.3 0.2 0.6 3.9 0.2 0.6 0.5 0.2 0.3 0.3 0.3 0.3 1.3 1.8 3.4 0.9 0.1 0.4 2.1 1.8 1.2 3.7 2.2 2.9 0.7 1.4 1.1 0.9 1.1 2.0 2.9 1.5 4.0 1.5 3.2 4.9 0.8 3.3 0.4 1.6 1.9 0.3 0.9 1.3 0.3 0.7 0.9 2.5 2.9 0.6 1.7 1.3 1.0 2.9 1.6 1.6 1.9 2.0 3.4 3.3 1.7 0.8 0.9 2.0 1.0 1.4 1.1 2.0 2.8 1.7 0.2 2.5 1.0 1.0 1.4 1.5 1.7 3.0 0.7 1.2 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.6 0.2 0.6 0.3 0.2 0.2 0.3 0.2 0.3 0.5 0.0 4.4 6.2 0.7 0.9 1.4 1.8 3.4 2.1 1.0 1.5 0.9 0.0 2.2 5.5 4.2 3.5 0.2 0.5 5.9 0.6 13.7 0.9 0.9 0.7 0.0 2.1 3.3 1.3 2.0 3.6 0.0 0.9 0.0 1.1 0.4 1.1 1.1 0.0 3.4 0.5 0.0 0.3 1.1 19.2 1.2 0.5 1.8 1.0 0.1 1.3 0.0 3.5 6.5 0.5 0.3 0.0 0.2 0.6 1.4 5.3 1.8 4.8 0.0 1.4 1.2 8.0 6.2 0.7 0.3 1.2 0.7 2.4 1.5 0.9 DEPDC5 "DEP.5, KIAA0645" ENSG00000100150 "DEP domain containing 5, GATOR1 subcomplex subunit" O75140 22 31753867-31908033 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "GTPase activation" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 31.9;Inhibitory neurons: 29.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 34.8" "Lineage enriched" "Detected in all" 5 "granulocytes: 34.8" "Cell line enhanced" "Detected in all" "U-698: 31.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054969, HPA055619" Uncertain NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 35: Non-specific - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 52: Non-specific - Transcription" "HPA054969: AB_2682655, HPA055619: AB_2682864" "unprognostic (5.68e-2)" "unprognostic (1.16e-2)" "unprognostic (8.98e-3)" "unprognostic (8.83e-2)" "unprognostic (5.60e-2)" "unprognostic (7.87e-3)" "unprognostic (5.93e-2)" "unprognostic (1.12e-2)" "unprognostic (2.95e-1)" "unprognostic (1.78e-1)" "unprognostic (4.59e-3)" "unprognostic (6.64e-2)" "prognostic favorable (2.46e-5)" "unprognostic (5.66e-2)" "unprognostic (7.88e-2)" "unprognostic (1.26e-1)" "prognostic favorable (4.86e-5)" 6.3 7.7 6.4 5.1 6.5 4.4 5.6 8.7 10.8 8.7 5.8 7.4 3.0 6.0 3.4 7.2 6.6 3.5 4.8 6.5 6.3 5.5 9.9 5.3 6.3 6.0 5.8 11.3 4.2 4.9 6.2 3.6 6.2 5.5 5.2 4.0 6.0 3.0 5.9 6.4 8.5 3.7 5.3 9.4 6.2 7.4 6.5 4.9 5.7 3.8 9.7 6.6 7.1 8.6 5.7 5.0 9.1 5.7 4.5 4.7 7.4 3.9 6.4 5.1 6.8 6.8 3.4 13.0 1.5 5.5 4.1 5.8 6.3 6.3 9.1 6.7 5.8 6.1 6.1 6.7 4.4 20.6 19.0 5.2 3.2 9.6 4.8 4.3 9.3 4.8 4.3 3.9 7.3 5.5 5.8 5.8 4.6 9.9 2.1 11.2 10.0 7.4 6.0 12.0 6.0 6.7 7.8 4.2 5.2 6.6 4.4 11.5 8.0 5.0 6.0 5.2 3.8 5.8 5.7 31.5 5.5 6.0 5.1 34.8 2.9 15.2 2.6 3.4 3.0 6.8 1.9 1.5 2.5 4.2 3.0 3.8 1.8 4.2 3.7 1.8 2.3 1.3 6.4 6.5 8.7 10.8 6.5 6.3 6.0 5.8 6.2 5.3 6.5 8.6 4.7 0.0 3.9 20.5 12.0 2.7 1.8 3.0 5.2 4.9 4.5 2.9 4.3 2.8 5.5 7.3 2.1 3.8 4.5 10.4 3.9 5.1 1.3 4.2 6.1 5.1 13.2 2.1 31.9 4.9 3.1 4.3 6.6 6.5 5.7 18.2 4.2 4.9 3.5 16.8 29.6 6.2 6.1 3.1 2.2 2.2 1.8 6.9 3.6 24.4 3.9 4.2 5.2 23.1 24.3 4.7 5.6 2.6 4.4 1.6 4.7 2.8 5.2 5.6 6.6 3.1 3.1 4.8 5.2 4.3 2.3 2.3 5.3 11.4 5.0 1.8 DEPDC7 ENSG00000121690 "DEP domain containing 7" Q96QD5 11 33015876-33033582 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 29.0;kidney: 19.6;liver: 74.0;testis: 28.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 34.8;Early spermatids: 153.3;Extravillous trophoblasts: 47.0;Proximal enterocytes: 33.2;Spermatocytes: 42.3" "Cancer enhanced" "Detected in many" "liver cancer: 6.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 6.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "LHCN-M2: 53.7;RH-30: 40.1;SiHa: 37.3;SK-MEL-30: 34.4;U-2197: 34.1" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA015800 Approved Nucleoplasm,Nucleoli,Cytosol Yes No "Cluster 2: Granulocytes - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoli "Nucleoplasm, Cytosol" "HPA015800: AB_1847610" "unprognostic (2.34e-1)" "unprognostic (5.57e-2)" "unprognostic (1.27e-1)" "unprognostic (2.27e-1)" "unprognostic (2.66e-2)" "unprognostic (7.26e-2)" "prognostic favorable (7.26e-4)" "unprognostic (1.80e-1)" "unprognostic (1.22e-1)" "unprognostic (2.92e-1)" "unprognostic (1.17e-3)" "unprognostic (8.99e-2)" "unprognostic (1.89e-2)" "unprognostic (9.30e-2)" "unprognostic (8.09e-3)" "unprognostic (2.64e-1)" "unprognostic (2.94e-2)" 0.6 0.8 2.5 1.9 3.2 1.8 0.9 2.9 3.7 2.8 2.7 4.6 24.6 1.0 2.2 4.4 0.9 4.4 1.1 2.6 2.7 19.6 74.0 0.9 0.7 3.2 2.7 1.6 3.8 2.3 0.8 1.5 3.0 1.9 5.1 0.1 2.0 1.5 4.9 6.0 29.0 1.7 2.8 0.3 3.0 28.2 2.7 2.9 0.5 0.9 1.5 1.2 3.4 4.9 9.4 5.2 7.3 3.3 3.8 3.6 4.9 16.2 5.4 9.8 13.0 13.5 0.9 0.0 3.7 16.2 4.5 9.4 10.8 3.8 11.5 0.0 14.9 2.5 16.1 19.3 3.2 9.1 10.9 4.6 5.7 5.7 4.2 5.3 0.0 0.0 6.2 0.0 53.7 1.0 0.0 14.6 4.8 7.7 0.0 0.0 40.1 0.1 3.2 1.3 1.6 4.2 37.3 6.6 34.4 5.1 1.7 4.7 0.0 6.3 10.4 34.1 10.6 0.0 0.0 0.1 2.3 0.0 31.5 4.1 0.5 6.7 0.2 0.1 0.0 0.0 0.4 0.2 3.2 0.0 1.9 2.1 0.0 2.4 0.0 1.2 0.0 0.4 2.5 3.2 2.9 3.7 2.6 2.7 3.2 2.7 3.0 2.8 2.7 4.9 0.2 0.0 0.0 1.0 0.0 34.8 12.8 4.5 12.5 0.0 0.2 0.6 0.1 1.5 0.9 0.0 0.0 0.5 0.5 6.0 3.9 0.9 153.3 0.2 0.2 0.3 3.5 3.2 0.1 0.6 47.0 1.6 0.0 0.1 2.5 0.1 1.4 22.6 3.1 0.0 0.4 2.4 0.0 0.6 9.5 16.3 1.5 1.7 1.8 3.7 1.2 0.0 0.0 3.5 10.4 0.8 0.6 1.2 0.1 2.4 33.2 18.4 0.9 0.0 0.0 4.5 1.4 42.3 6.5 6.6 7.4 1.5 0.7 0.2 2.4 1.6 DERL2 "CGI-101, derlin-2, F-LAN-1, F-LANa, FLANa" ENSG00000072849 "Derlin 2" Q9GZP9 17 5471254-5486811 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Host-virus interaction, Unfolded protein response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 259.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037287, HPA048957, HPA056551" Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 29: Non-specific - Vesicular transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Endoplasmic reticulum" "CAB037287: AB_1078641, HPA048957: AB_2680570, HPA056551: AB_2683171" "unprognostic (2.54e-1)" "unprognostic (5.30e-2)" "unprognostic (5.83e-2)" "prognostic favorable (7.26e-4)" "unprognostic (1.51e-2)" "unprognostic (4.70e-2)" "unprognostic (1.36e-1)" "unprognostic (2.63e-1)" "unprognostic (2.17e-1)" "unprognostic (1.12e-3)" "unprognostic (1.73e-3)" "unprognostic (5.23e-2)" "prognostic unfavorable (6.49e-4)" "unprognostic (1.91e-1)" "unprognostic (1.82e-1)" "unprognostic (3.73e-1)" "unprognostic (2.91e-2)" 14.5 18.8 5.7 16.4 6.0 33.9 12.9 6.3 7.6 13.1 7.0 12.9 14.9 12.8 29.6 15.3 14.0 17.3 10.2 5.4 6.2 14.0 28.0 11.3 18.2 6.4 6.4 12.8 28.5 14.7 12.1 13.4 6.6 14.0 12.3 8.1 28.3 11.4 10.6 10.1 17.5 12.4 6.2 15.1 15.5 24.4 6.1 10.8 24.6 4.9 15.4 14.9 11.1 7.6 32.0 40.4 18.8 31.7 31.5 23.6 24.0 44.5 36.1 30.0 36.4 27.8 27.9 22.0 39.2 28.5 33.6 35.0 13.2 25.7 29.9 29.3 27.6 10.8 25.8 30.0 43.4 8.1 25.2 22.0 21.0 40.6 34.9 26.4 31.4 22.4 12.0 37.5 40.9 16.5 17.3 12.3 18.2 20.7 16.0 20.8 26.6 16.3 32.5 16.2 7.9 23.2 27.1 18.5 47.6 20.6 24.8 11.8 23.9 35.4 23.9 21.8 43.3 26.0 31.4 20.0 37.0 20.1 28.4 71.9 62.6 77.0 64.6 70.4 67.2 66.5 61.2 68.7 48.2 65.5 48.3 59.3 59.9 60.4 56.4 69.2 81.0 117.5 5.7 6.0 6.3 7.6 5.4 6.2 6.4 6.4 6.6 6.2 6.1 7.6 36.1 12.8 23.9 12.4 46.4 34.3 50.5 157.7 27.9 17.7 48.4 48.5 31.3 35.8 82.7 44.1 22.9 70.6 70.5 28.1 15.6 79.9 259.2 32.5 41.7 35.7 18.5 35.3 8.1 89.7 103.6 51.3 22.4 41.6 49.4 38.8 30.4 57.5 74.5 11.8 9.0 37.2 89.5 33.6 44.8 63.4 43.8 37.8 46.2 6.5 64.7 35.1 48.4 6.6 16.2 86.7 25.2 35.3 119.9 68.7 37.1 50.4 55.6 24.8 59.2 33.9 54.3 126.4 45.4 26.2 31.1 96.2 47.7 45.8 30.4 62.8 DFFA "DFF-45, DFF1, DFF45, ICAD" ENSG00000160049 "DNA fragmentation factor subunit alpha" O00273 1 10456522-10472529 "Plasma proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002679, HPA018859, HPA019938, HPA025230" Supported Supported "Plasma membrane,Cytosol" NA NA 8700 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Plasma membrane, Cytosol" "CAB002679: , HPA018859: AB_1847622, HPA019938: AB_1847625, HPA025230: AB_1847623" "unprognostic (1.23e-1)" "unprognostic (2.63e-1)" "unprognostic (1.06e-1)" "unprognostic (3.59e-2)" "unprognostic (1.57e-2)" "unprognostic (1.81e-1)" "prognostic unfavorable (9.46e-4)" "unprognostic (1.55e-1)" "unprognostic (9.24e-3)" "unprognostic (3.57e-2)" "unprognostic (1.50e-1)" "unprognostic (1.91e-1)" "prognostic favorable (1.57e-9)" "unprognostic (1.21e-2)" "unprognostic (3.46e-2)" "unprognostic (3.89e-2)" "unprognostic (1.88e-1)" 13.3 12.6 15.0 12.0 18.0 6.5 12.6 19.7 16.5 11.1 14.2 11.3 12.1 11.7 9.8 16.7 13.0 10.8 12.1 14.9 17.2 16.8 13.2 11.3 12.4 17.4 18.7 15.3 11.4 18.0 9.2 20.1 17.5 11.8 12.2 12.2 10.9 12.3 12.3 10.9 11.1 16.1 16.1 10.7 12.1 9.8 18.3 13.3 12.3 13.9 16.2 14.4 10.1 18.3 37.8 36.8 31.0 35.4 25.7 24.3 15.1 52.5 33.6 53.4 39.6 88.4 48.4 79.9 33.1 44.5 29.7 30.3 60.5 62.2 53.7 31.9 41.8 39.9 37.6 35.8 41.8 49.3 25.4 30.5 30.6 84.4 67.4 29.1 41.3 39.3 72.6 17.6 38.4 48.0 48.8 22.2 27.2 28.3 42.4 41.3 37.1 40.1 48.5 28.6 36.5 35.6 48.9 42.1 58.0 26.6 27.0 17.0 43.4 24.9 34.0 46.4 35.0 21.6 32.5 114.3 26.5 45.7 38.5 1.8 11.2 8.6 15.2 9.1 11.7 16.6 10.3 13.5 10.6 15.8 10.7 13.0 1.4 17.5 12.3 12.4 16.2 10.5 15.0 18.0 19.7 16.5 14.9 17.2 17.4 18.7 17.5 16.1 18.3 18.3 26.9 44.8 34.3 3.3 23.5 34.4 39.0 43.8 30.1 21.1 20.5 25.0 23.7 32.9 36.6 18.4 108.4 91.1 22.8 12.6 37.2 46.5 32.0 22.4 31.6 34.0 34.2 15.6 6.5 39.1 64.9 25.1 20.9 23.8 24.7 35.6 31.4 31.0 41.8 20.2 8.3 17.3 28.5 22.9 13.8 73.2 30.1 17.0 10.6 3.7 37.4 23.3 28.8 5.0 6.9 49.1 10.6 32.4 19.3 48.1 25.0 57.8 26.0 34.0 19.7 29.9 26.9 35.7 28.4 32.0 40.6 66.4 18.5 43.9 27.9 38.9 DGCR2 "DGS-C, IDD, KIAA0163, LAN, SEZ-12" ENSG00000070413 "DiGeorge syndrome critical region gene 2" P98153 22 19036282-19122454 "Predicted membrane proteins" "Cell adhesion" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000873 Uncertain NA NA 84000 "Cluster 5: Granulocytes - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA000873: AB_1847632" "unprognostic (1.68e-1)" "unprognostic (4.27e-2)" "unprognostic (4.03e-2)" "unprognostic (1.33e-2)" "unprognostic (6.28e-2)" "unprognostic (8.51e-2)" "unprognostic (1.05e-1)" "unprognostic (6.86e-2)" "unprognostic (2.49e-1)" "unprognostic (1.00e-1)" "unprognostic (1.25e-1)" "unprognostic (2.06e-2)" "prognostic favorable (8.72e-7)" "unprognostic (3.63e-2)" "unprognostic (2.29e-1)" "unprognostic (6.27e-2)" "unprognostic (6.28e-3)" 25.3 28.6 45.7 14.9 40.4 7.4 26.4 34.6 48.9 30.0 24.7 34.0 26.2 32.9 12.9 46.5 27.7 19.0 33.6 44.1 42.8 31.1 30.6 28.6 16.8 45.2 43.3 35.9 44.6 26.3 33.1 16.4 43.6 34.7 16.0 9.1 33.7 23.5 27.2 61.3 28.8 15.6 38.3 25.5 30.2 25.3 52.0 16.7 39.8 19.5 12.5 31.2 32.1 38.6 43.2 26.5 32.6 58.3 57.9 23.2 31.8 28.3 34.8 27.2 26.8 45.7 47.9 22.7 38.7 30.7 19.4 79.7 24.2 27.2 11.4 19.4 44.4 15.3 16.0 37.0 35.1 28.8 33.4 33.3 61.6 21.1 24.3 23.4 30.3 14.2 115.6 19.3 14.0 45.0 15.2 31.0 27.3 67.8 19.1 26.5 34.4 8.9 46.2 46.8 44.4 32.8 52.1 36.0 32.6 17.6 33.5 25.9 27.0 50.0 25.6 26.3 23.1 21.5 8.5 14.9 23.7 16.5 38.9 9.5 10.3 16.5 6.1 5.3 5.3 4.3 6.5 6.1 6.8 4.7 7.8 6.4 23.5 4.6 3.9 4.0 9.5 11.3 45.7 40.4 34.6 48.9 44.1 42.8 45.2 43.3 43.6 38.3 52.0 38.6 16.4 19.2 27.0 34.3 10.0 9.7 10.8 17.1 17.6 30.1 23.4 20.6 18.0 30.0 23.3 27.6 14.6 17.2 9.5 59.7 0.0 24.9 13.7 9.6 11.2 13.7 19.9 4.2 35.7 21.9 19.0 13.5 27.0 16.9 8.2 24.5 21.4 27.3 12.1 37.0 43.7 30.3 18.3 18.5 4.7 22.2 17.1 10.4 8.8 22.5 16.4 18.5 11.3 54.8 32.6 30.9 24.0 22.6 11.1 18.8 27.7 10.6 14.0 23.0 13.1 14.4 15.1 12.6 12.9 22.1 12.4 10.8 11.8 17.7 28.4 16.8 DGCR6L FLJ10666 ENSG00000128185 "DiGeorge syndrome critical region gene 6 like" Q9BY27 22 20314238-20320080 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 5 "Late spermatids: 2787.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 43: Testis - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (1.91e-1)" "prognostic favorable (3.82e-5)" "unprognostic (2.74e-2)" "unprognostic (4.61e-3)" "unprognostic (3.97e-2)" "unprognostic (2.46e-1)" "unprognostic (2.61e-1)" "prognostic favorable (5.37e-4)" "unprognostic (1.44e-1)" "unprognostic (4.39e-2)" "unprognostic (3.29e-3)" "unprognostic (9.07e-3)" "unprognostic (6.72e-3)" "unprognostic (4.37e-2)" "unprognostic (2.91e-1)" "unprognostic (1.26e-1)" "unprognostic (2.97e-1)" 34.2 44.8 75.9 15.3 73.2 30.9 36.3 68.7 95.7 38.0 72.4 46.5 19.8 33.6 23.8 41.2 31.7 18.7 67.8 72.9 71.4 57.6 152.6 28.6 24.7 71.2 71.7 36.3 43.1 42.1 43.3 12.5 71.9 51.0 11.4 8.6 45.2 29.0 81.1 54.1 29.8 15.3 71.2 33.8 40.9 132.0 74.1 27.6 45.9 44.1 14.6 39.9 35.3 69.5 34.0 38.0 25.5 64.5 36.6 36.6 26.7 32.4 37.7 58.7 42.6 19.7 16.4 9.1 41.4 35.9 23.7 33.8 19.3 39.0 9.6 43.7 97.6 21.7 26.6 36.8 43.3 46.6 21.0 41.0 35.4 23.0 24.7 22.7 41.4 42.3 99.9 39.4 38.3 79.2 35.1 42.4 18.7 67.2 56.1 61.0 58.5 17.7 31.1 26.3 50.4 36.9 53.3 34.7 60.6 10.3 50.3 37.0 32.5 69.4 80.3 37.1 32.1 34.9 39.5 20.9 56.1 58.5 47.5 115.6 102.0 145.5 104.6 93.3 104.0 81.7 130.7 117.7 93.9 73.5 119.9 113.9 34.0 139.1 92.7 88.2 129.8 120.4 75.9 73.2 68.7 95.7 72.9 71.4 71.2 71.7 71.9 71.2 74.1 69.5 43.6 28.9 30.2 4.9 29.7 43.7 34.2 53.4 33.0 18.6 79.4 106.3 80.3 57.2 41.1 35.0 4.2 67.7 43.1 65.2 133.1 72.2 529.8 28.0 23.2 40.2 52.8 37.2 6.3 63.0 86.4 43.3 26.0 17.5 39.3 38.5 62.4 166.9 80.2 28.6 7.3 64.4 34.6 78.3 52.9 2787.0 70.2 41.7 56.9 1.9 55.5 58.2 95.8 6.0 7.9 51.7 58.5 70.7 44.2 26.2 166.0 164.5 42.5 24.9 46.0 23.6 47.2 117.3 91.0 62.3 60.9 21.9 56.7 36.2 69.0 33.9 DGLUCY "C14orf159, FLJ39975" ENSG00000133943 "D-glutamate cyclase" Q7Z3D6 14 91060333-91225632 "Enzymes, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 163.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 28.9;Collecting duct cells: 29.5;Cytotrophoblasts: 30.9;Endometrial ciliated cells: 29.4;Granulosa cells: 49.8;Hofbauer cells: 31.7;Theca cells: 35.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 200.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA041423, HPA052932" Approved Supported Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 39: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 40: Granulosa cells - Unknown function" Cytosol "HPA041423: AB_10795540, HPA052932: AB_2681991" "unprognostic (5.02e-2)" "unprognostic (1.01e-2)" "unprognostic (1.56e-1)" "prognostic favorable (4.28e-4)" "unprognostic (1.28e-1)" "unprognostic (2.26e-1)" "unprognostic (3.58e-2)" "prognostic favorable (9.48e-5)" "unprognostic (3.56e-1)" "prognostic favorable (7.28e-4)" "unprognostic (2.30e-1)" "unprognostic (1.74e-1)" "prognostic favorable (3.77e-15)" "unprognostic (1.50e-1)" "unprognostic (9.51e-2)" "unprognostic (2.75e-2)" "unprognostic (2.57e-3)" 23.9 32.2 38.5 21.4 46.0 21.7 16.7 53.5 49.2 25.0 76.1 33.5 25.1 26.0 17.2 28.4 38.6 22.6 122.3 36.6 39.8 35.6 24.9 25.0 21.6 45.5 51.3 22.9 16.8 47.9 21.5 16.6 42.1 22.8 30.4 8.3 32.2 34.1 143.0 25.6 23.7 32.0 38.0 33.6 38.1 19.0 45.4 27.3 30.1 163.6 19.9 31.9 20.2 45.2 6.2 16.4 8.0 20.1 32.8 30.6 21.0 6.6 17.7 19.3 19.6 10.9 46.7 41.3 46.0 18.8 24.9 18.0 23.0 24.7 7.9 22.8 9.5 27.7 9.1 13.8 47.8 28.5 38.2 47.5 10.5 10.6 4.0 25.3 34.6 22.8 14.0 54.4 18.4 1.4 22.7 27.0 16.4 0.8 1.4 38.2 15.7 30.9 32.7 25.9 22.4 11.2 10.4 17.8 7.3 8.4 32.0 24.5 24.7 5.7 4.8 17.1 5.9 30.9 23.8 14.0 29.6 36.8 3.8 67.5 48.8 30.8 30.1 69.4 30.3 34.0 19.3 24.5 72.9 22.4 15.9 20.0 200.5 21.0 60.7 22.0 45.2 29.0 38.5 46.0 53.5 49.2 36.6 39.8 45.5 51.3 42.1 38.0 45.4 45.2 19.2 28.9 16.4 0.0 4.3 0.0 0.0 0.0 0.0 0.0 11.5 13.2 0.0 0.0 5.6 29.5 0.0 30.9 12.5 0.0 21.5 17.6 0.0 29.4 14.8 6.2 0.0 0.0 0.0 5.8 15.8 7.4 0.0 25.0 7.6 49.8 0.0 0.0 31.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.2 0.0 0.0 7.2 0.0 0.0 0.0 0.0 6.3 0.0 0.0 2.7 0.0 0.0 17.0 5.1 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 16.8 8.7 35.6 0.0 0.0 DHCR24 "DCE, KIAA0018, seladin-1" ENSG00000116133 "24-dehydrocholesterol reductase" Q15392 1 54849627-54887195 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 1129.5;liver: 623.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 298.1;Alveolar cells type 2: 682.3;Hepatocytes: 1091.4;Theca cells: 442.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 1031.9" "Low region specificity" "Detected in all" "HPA017981, CAB037247, HPA063005" Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 18: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 15: Hepatocytes - Hemostasis" "CAB037247: AB_796187, HPA017981: AB_2732422, HPA063005: AB_2684919" "unprognostic (2.88e-1)" "unprognostic (1.80e-2)" "unprognostic (4.99e-3)" "prognostic unfavorable (1.05e-5)" "unprognostic (1.69e-1)" "unprognostic (2.61e-1)" "unprognostic (1.54e-2)" "unprognostic (1.85e-1)" "unprognostic (1.68e-1)" "unprognostic (1.86e-1)" "unprognostic (6.18e-3)" "unprognostic (3.35e-1)" "unprognostic (7.82e-3)" "unprognostic (5.48e-2)" "unprognostic (1.83e-1)" "unprognostic (1.70e-1)" "unprognostic (3.97e-2)" 58.3 1129.5 35.7 19.8 58.5 1.6 104.8 125.3 73.0 54.9 30.4 55.6 62.2 13.1 1.6 296.1 60.4 42.2 18.0 55.9 63.9 48.6 623.5 215.9 9.4 216.2 91.3 28.5 30.5 157.9 17.0 21.6 158.9 128.6 40.5 15.8 136.2 8.3 197.7 247.6 29.6 12.6 129.3 134.1 98.9 74.2 87.9 10.1 15.4 11.1 33.9 13.5 103.9 280.7 342.1 58.5 210.6 257.1 1031.9 219.0 50.5 94.8 160.3 130.7 268.6 341.6 210.2 55.3 191.5 82.4 427.4 319.2 250.5 501.3 118.3 8.3 159.6 303.3 131.8 421.7 168.9 126.7 68.2 161.0 429.0 397.6 74.7 66.7 67.2 124.5 224.7 0.2 50.2 143.5 25.8 111.4 592.0 90.7 164.2 0.3 54.2 166.3 735.3 257.1 144.5 53.2 185.0 337.5 123.1 221.6 441.5 143.3 62.2 45.3 130.0 66.1 183.9 22.7 55.0 91.2 32.8 215.3 60.4 5.1 1.5 0.7 6.0 1.8 0.3 3.7 2.5 2.6 5.2 1.3 2.2 2.9 0.0 2.7 0.7 3.0 0.4 4.4 35.7 58.5 125.3 73.0 55.9 63.9 216.2 91.3 158.9 129.3 87.9 280.7 6.2 298.1 682.3 12.4 13.3 31.5 17.3 150.6 79.1 9.7 87.9 33.1 15.3 145.8 205.2 68.0 0.0 35.2 6.4 133.3 3.9 55.3 22.9 14.5 5.8 13.5 24.0 71.6 14.5 76.5 34.4 17.5 38.7 44.7 32.2 26.4 111.0 1091.4 28.0 5.0 8.7 39.2 69.2 68.9 8.2 77.2 14.0 9.4 14.2 1.9 6.8 3.6 2.1 5.5 62.6 48.6 27.7 7.9 1.8 52.4 22.6 14.4 136.3 6.4 0.0 1.5 23.2 5.4 14.7 145.4 80.4 30.6 10.6 442.4 35.2 45.2 DHX30 "DDX30, FLJ11214, KIAA0890" ENSG00000132153 "DExH-box helicase 30" Q7L2E3 3 47802909-47850195 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Ribosome biogenesis" "Helicase, Hydrolase, RNA-binding" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034806 Supported Supported Mitochondria,Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 43: Testis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Mitochondria Cytosol "HPA034806: AB_10601364" "unprognostic (2.00e-1)" "unprognostic (8.37e-2)" "unprognostic (3.27e-1)" "unprognostic (2.14e-2)" "unprognostic (3.04e-1)" "unprognostic (1.62e-1)" "unprognostic (1.27e-3)" "unprognostic (1.14e-1)" "unprognostic (1.16e-1)" "unprognostic (1.74e-1)" "unprognostic (1.10e-3)" "unprognostic (1.42e-2)" "prognostic favorable (1.37e-6)" "unprognostic (4.12e-2)" "unprognostic (1.43e-1)" "unprognostic (2.81e-1)" "unprognostic (2.22e-1)" 22.6 24.6 23.7 17.1 23.3 22.2 22.9 21.4 26.3 26.4 24.8 26.8 16.2 27.6 10.4 23.6 24.8 14.9 28.8 23.5 22.4 26.8 25.2 21.3 20.1 24.0 23.5 27.9 24.1 28.9 32.1 17.5 24.6 26.6 10.9 12.7 21.6 18.2 37.1 27.6 22.3 15.9 20.3 27.3 25.2 54.2 23.8 23.3 24.8 21.0 14.3 25.2 22.8 24.2 21.9 52.3 54.5 56.2 24.6 20.2 35.3 39.0 33.4 65.1 46.5 56.9 42.6 66.4 32.0 37.0 51.2 30.3 73.7 52.1 23.1 49.6 86.1 59.6 76.0 58.6 40.7 56.0 58.3 33.0 33.4 68.1 49.7 28.4 44.0 57.5 82.0 40.6 31.8 57.1 82.2 59.3 60.7 30.2 84.0 44.6 30.6 62.2 32.0 53.6 41.6 61.6 39.6 54.1 31.1 25.0 38.5 58.8 32.2 40.6 51.0 46.7 73.9 56.2 75.3 61.8 42.8 48.3 49.9 14.1 10.7 7.8 16.2 10.6 12.4 10.4 12.4 16.3 13.9 8.7 11.7 12.7 1.6 9.6 11.6 7.9 15.3 14.7 23.7 23.3 21.4 26.3 23.5 22.4 24.0 23.5 24.6 20.3 23.8 24.2 31.1 38.5 46.7 30.7 34.7 18.1 25.7 38.7 39.3 49.0 34.6 35.6 38.1 32.9 34.1 51.5 43.8 41.7 33.1 37.6 66.5 37.8 129.5 59.2 31.7 32.4 40.1 38.5 32.8 36.3 22.8 26.7 42.3 33.2 23.5 40.7 27.5 50.8 35.9 58.9 36.6 25.8 40.7 29.6 17.6 123.8 24.8 24.4 19.6 13.1 32.5 46.3 28.8 22.1 28.7 46.0 41.0 30.1 39.9 28.6 40.5 83.5 49.9 52.8 32.9 27.3 28.6 145.4 50.2 33.5 19.9 29.6 29.7 36.6 38.5 26.3 DIAPH2 "DIA, DIA2, POF, POF2" ENSG00000147202 "Diaphanous related formin 2" O60879 X 96684663-97604997 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Oogenesis" "Developmental protein" "Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 171.0;Late spermatids: 177.8;Microglial cells: 301.7;Oligodendrocyte precursor cells: 281.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005647, CAB015461, CAB068183, CAB068184" Enhanced Supported "Nucleoli,Endoplasmic reticulum,Vesicles" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 59: Non-specific - Translation" "Cluster 32: U-937 - Innate immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Endoplasmic reticulum, Vesicles" Nucleoli "CAB015461: AB_831223, CAB068183: AB_2665693, CAB068184: AB_2665694, HPA005647: AB_1078657" "unprognostic (5.75e-2)" "unprognostic (4.13e-3)" "unprognostic (1.48e-1)" "prognostic unfavorable (2.16e-5)" "unprognostic (1.58e-1)" "unprognostic (6.48e-2)" "unprognostic (4.06e-1)" "unprognostic (1.07e-2)" "unprognostic (2.41e-1)" "unprognostic (1.43e-2)" "prognostic unfavorable (2.12e-4)" "unprognostic (3.39e-2)" "prognostic unfavorable (3.90e-4)" "unprognostic (6.44e-2)" "unprognostic (3.11e-2)" "unprognostic (6.99e-3)" "unprognostic (6.08e-3)" 10.7 3.3 3.7 6.4 6.4 17.7 7.0 0.0 4.3 10.6 17.3 8.6 4.3 5.5 3.5 7.7 6.7 5.7 5.4 6.4 3.1 3.1 12.3 8.2 3.8 0.6 0.9 7.7 4.9 7.0 2.0 12.5 1.0 6.1 8.7 3.0 6.6 7.6 12.0 5.3 5.3 7.4 0.2 3.8 7.4 9.4 1.5 6.0 3.9 9.1 3.9 7.4 9.8 1.8 0.0 6.5 3.1 6.3 17.1 28.3 0.0 11.2 11.8 5.9 12.4 5.5 12.3 18.5 8.7 9.7 11.3 0.0 16.6 1.7 7.6 0.5 9.5 0.0 7.4 5.9 14.2 24.3 8.2 14.3 6.0 8.0 24.6 8.0 11.6 13.6 0.0 14.9 11.2 5.3 9.2 10.0 24.4 0.1 9.4 0.0 16.5 0.0 3.4 9.8 0.0 6.3 0.0 3.2 9.0 18.8 2.7 13.2 14.8 12.6 5.8 10.6 7.3 0.2 0.0 15.3 10.7 24.1 7.6 0.0 3.1 3.3 1.1 2.8 0.9 1.7 1.2 1.4 2.3 1.3 0.8 0.7 0.3 0.7 2.5 2.2 0.7 0.6 3.7 6.4 0.0 4.3 6.4 3.1 0.6 0.9 1.0 0.2 1.5 1.8 61.7 32.1 51.1 21.2 18.8 10.8 6.8 11.9 11.4 5.5 9.9 8.1 20.2 15.7 15.0 20.2 0.0 65.2 21.5 36.6 7.9 18.6 80.5 51.2 46.2 31.2 24.6 6.1 171.0 23.4 16.8 35.2 41.8 41.7 7.6 36.1 8.2 26.1 21.0 0.0 90.0 32.3 4.1 29.6 19.3 177.8 45.1 34.7 8.8 301.7 32.7 13.0 10.3 281.0 41.2 38.4 39.3 20.3 11.6 8.0 11.9 9.4 57.1 13.7 26.3 46.7 32.7 7.5 12.9 17.6 18.3 118.3 19.0 19.0 32.5 6.0 DISP3 "KIAA1337, PTCHD2" ENSG00000204624 "Dispatched RND transporter family member 3" Q9P2K9 1 11479155-11537551 "Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol metabolism, Differentiation, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "brain: 9.8;pituitary gland: 3.5;retina: 4.6;testis: 6.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "glioma: 2.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 4.9;NTERA-2: 2.1;SCLC-21H: 2.0;SH-SY5Y: 6.8;SiHa: 1.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054579 Uncertain Uncertain Nucleoplasm,Cytosol NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Cytosol "HPA054579: AB_2682529" "unprognostic (4.93e-2)" "unprognostic (2.23e-2)" "unprognostic (1.61e-1)" "unprognostic (9.55e-3)" "unprognostic (1.80e-1)" "unprognostic (2.73e-1)" "unprognostic (6.12e-2)" "unprognostic (7.75e-2)" "unprognostic (3.62e-1)" "unprognostic (1.08e-1)" "unprognostic (4.34e-3)" "unprognostic (4.86e-2)" "unprognostic (3.80e-2)" "unprognostic (3.88e-1)" "unprognostic (7.06e-2)" "unprognostic (1.79e-4)" "unprognostic (1.34e-1)" 0.0 0.3 7.1 0.1 9.4 0.0 0.0 4.1 9.8 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.1 8.6 6.9 0.1 0.0 0.1 0.1 3.3 5.7 0.1 0.5 0.0 3.5 0.0 4.6 0.5 0.0 4.6 0.0 0.0 0.0 0.0 0.2 0.0 3.7 0.3 0.1 6.3 7.8 0.2 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 4.9 0.4 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.5 0.0 0.0 2.1 0.0 0.0 0.5 0.0 1.3 0.0 0.1 2.0 6.8 1.6 0.0 0.0 1.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 1.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.1 9.4 4.1 9.8 8.6 6.9 3.3 5.7 4.6 3.7 7.8 3.3 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 DKK3 "REIC, RIG" ENSG00000050165 "Dickkopf WNT signaling pathway inhibitor 3" Q9UBP4 11 11956207-12009769 "Plasma proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "heart muscle: 1224.0" "Group enriched" "Detected in many" 7 "Cardiomyocytes: 884.3;Muller glia cells: 1960.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 6.2;memory CD8 T-cell: 3.8" "Lineage enriched" "Detected in single" 62 "T-cells: 6.2" "Cell line enhanced" "Detected in many" "BJ: 418.9;BJ hTERT+: 643.0;fHDF/TERT166: 614.4;hTERT-RPE1: 370.2;TIME: 349.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011868, CAB024949" Approved Supported "Nuclear bodies,Vesicles,Cytosol" "Secreted in other tissues" No No 18000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 5: Muller glia cells - Visual perception" Vesicles "Nuclear bodies, Cytosol" "CAB024949: , HPA011868: AB_1847716" "unprognostic (4.24e-2)" "unprognostic (6.40e-2)" "unprognostic (1.96e-1)" "unprognostic (7.84e-2)" "unprognostic (3.06e-3)" "unprognostic (6.58e-3)" "unprognostic (1.14e-2)" "unprognostic (1.58e-1)" "unprognostic (3.31e-3)" "unprognostic (5.28e-2)" "unprognostic (4.51e-2)" "unprognostic (3.87e-2)" "prognostic unfavorable (6.31e-5)" "unprognostic (7.41e-3)" "unprognostic (1.09e-1)" "unprognostic (2.97e-2)" "unprognostic (1.02e-3)" 31.2 79.1 110.7 10.0 183.6 0.2 26.0 12.6 135.2 89.7 104.8 53.2 14.6 47.0 16.7 29.7 23.0 67.0 1224.0 147.7 80.2 17.0 5.6 123.7 8.5 95.1 54.3 38.1 18.2 34.2 38.2 25.0 46.8 59.4 13.0 204.1 30.9 78.1 7.8 29.7 24.6 43.1 83.9 33.2 31.7 30.9 99.9 4.7 16.4 18.8 5.4 40.9 48.3 121.6 1.5 13.1 18.1 0.1 15.3 29.7 0.6 418.9 643.0 182.4 205.5 9.6 3.2 0.0 44.8 614.4 96.8 64.4 1.5 181.9 69.5 0.1 0.5 0.0 1.7 0.0 113.6 0.0 0.3 45.3 60.0 61.9 151.3 370.2 195.3 0.0 0.2 0.4 256.4 0.0 0.1 0.4 8.6 0.0 0.5 0.1 1.2 0.1 62.5 0.6 0.5 53.2 2.0 0.0 0.2 47.9 0.2 0.5 349.7 107.5 82.8 11.2 110.3 0.1 0.0 0.3 18.1 0.0 103.5 0.0 0.0 0.0 0.5 0.0 6.2 0.0 0.6 3.8 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.3 110.7 183.6 12.6 135.2 147.7 80.2 95.1 54.3 46.8 83.9 99.9 121.6 5.8 3.2 3.0 94.3 0.1 45.6 59.5 70.3 93.4 31.6 3.2 103.2 884.3 0.0 12.8 0.0 12.5 0.5 0.4 0.0 0.0 0.8 104.3 0.7 8.4 32.9 1.8 0.0 90.4 0.2 0.8 106.1 7.1 0.6 1.3 17.0 66.8 0.4 20.4 13.5 83.7 0.1 0.0 1.3 12.5 88.5 20.5 1.4 64.0 38.4 0.0 1960.4 0.0 27.6 14.7 1.1 0.1 57.6 1.7 32.8 0.0 0.2 2.9 67.5 190.7 12.7 83.4 1.2 3.2 5.8 14.8 0.8 4.1 0.5 0.3 3.0 DLGAP4 "DAP4, KIAA0964, SAPAP4" ENSG00000080845 "DLG associated protein 4" Q9Y2H0 20 36306336-36528637 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 213.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-138 MG: 212.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054105, HPA056378" Approved Approved "Nucleoplasm,Focal adhesion sites" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Focal adhesion sites" "HPA054105: AB_2682381, HPA056378: " "unprognostic (1.11e-1)" "unprognostic (1.42e-1)" "unprognostic (9.00e-2)" "prognostic unfavorable (2.24e-5)" "unprognostic (1.35e-1)" "unprognostic (1.37e-1)" "prognostic unfavorable (3.73e-6)" "unprognostic (1.23e-1)" "prognostic favorable (9.88e-5)" "unprognostic (1.28e-1)" "unprognostic (2.18e-2)" "unprognostic (8.45e-2)" "prognostic unfavorable (2.48e-4)" "unprognostic (1.07e-1)" "unprognostic (1.13e-1)" "unprognostic (1.37e-1)" "unprognostic (1.53e-1)" 55.4 47.5 39.0 23.5 31.4 7.5 40.3 2.8 45.9 51.7 2.6 71.4 21.2 64.5 12.5 31.7 45.2 26.4 58.4 39.3 12.3 34.3 37.3 60.5 16.6 5.4 18.1 48.4 47.8 13.8 36.4 26.5 10.5 44.7 15.0 25.4 37.8 30.6 130.8 86.8 37.1 42.5 2.8 32.9 36.5 29.3 29.1 14.7 43.3 45.9 14.8 56.2 46.6 20.6 49.9 44.2 53.0 44.1 49.0 79.9 53.2 73.2 66.5 70.0 48.2 67.4 30.9 14.0 38.5 103.3 61.9 46.7 14.3 75.1 51.8 22.5 5.2 31.8 22.7 46.2 70.9 12.9 26.5 52.9 57.0 83.1 57.6 54.2 69.7 19.5 22.5 37.2 53.6 37.0 26.3 49.0 23.2 36.2 93.4 26.1 14.0 19.4 33.0 24.3 34.8 47.9 48.0 96.0 60.0 53.7 55.3 22.3 71.2 212.1 64.6 92.6 40.9 12.7 9.8 15.1 84.9 16.2 85.4 2.7 16.5 26.9 15.0 17.3 11.9 19.5 13.5 10.7 14.5 20.8 10.1 8.1 23.6 9.6 17.9 17.4 11.9 12.6 39.0 31.4 2.8 45.9 39.3 12.3 5.4 18.1 10.5 2.8 29.1 20.6 30.4 16.0 20.5 34.0 25.2 66.4 53.8 30.6 9.1 34.9 30.2 21.0 27.9 22.8 22.9 12.9 8.4 23.1 23.7 27.2 7.9 53.0 69.9 25.9 47.7 36.6 63.3 4.4 77.9 55.7 52.3 40.1 23.4 29.4 12.6 35.7 27.8 17.5 27.2 74.0 93.4 35.0 20.3 22.4 54.4 213.4 29.8 23.9 10.6 37.5 47.5 38.7 21.6 81.4 13.2 84.4 25.0 26.4 8.9 72.9 25.8 20.4 28.3 29.5 72.3 28.8 51.0 13.7 30.3 13.2 71.7 55.1 20.7 29.8 20.6 52.3 DLL1 ENSG00000198719 "Delta like canonical Notch ligand 1" O00548 6 170282206-170306565 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Notch signaling pathway" "Developmental protein" "Autism spectrum disorder, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 53.9" "Cell type enhanced" "Detected in many" "Adipocytes: 88.8;Basal keratinocytes: 66.9;Basal squamous epithelial cells: 82.0;Enteroendocrine cells: 51.9;Intestinal goblet cells: 80.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "NK-cell: 3.3" "Lineage enriched" "Detected in single" 8 "NK-cells: 3.3" "Cell line enhanced" "Detected in some" "HaCaT: 6.8;HBEC3-KT: 4.5;NB-4: 14.2;THP-1: 14.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA001255 Approved "Plasma membrane" NA NA 690000 "Cluster 48: NK-cells - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane" "HPA001255: " "unprognostic (1.03e-1)" "unprognostic (9.22e-2)" "unprognostic (2.17e-3)" "unprognostic (1.95e-1)" "unprognostic (2.89e-2)" "unprognostic (6.35e-2)" "unprognostic (1.63e-2)" "unprognostic (1.89e-1)" "unprognostic (9.22e-2)" "unprognostic (1.14e-2)" "unprognostic (1.39e-2)" "unprognostic (2.64e-2)" "unprognostic (5.23e-3)" "unprognostic (3.50e-1)" "unprognostic (1.83e-1)" "unprognostic (4.33e-2)" "unprognostic (1.66e-1)" 20.9 8.6 2.8 2.1 6.9 0.7 19.2 3.3 4.5 21.1 0.2 15.4 3.9 10.1 0.3 21.9 11.5 0.8 15.9 2.2 2.9 12.5 6.4 13.1 1.9 6.0 5.1 4.2 16.9 0.3 6.2 1.2 4.8 28.7 0.9 0.4 17.7 1.1 5.3 26.2 19.3 0.8 2.0 53.9 10.9 1.6 4.0 0.2 12.4 0.7 0.4 9.6 22.9 11.0 0.7 0.1 3.3 2.0 0.1 0.1 1.5 0.3 0.2 0.2 0.3 1.0 0.1 0.0 0.3 0.1 0.6 6.8 1.4 4.5 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 3.6 0.1 0.6 0.0 0.4 0.1 0.7 0.0 0.0 0.0 0.1 0.8 0.0 14.2 0.2 0.1 0.0 1.1 2.8 0.0 0.0 0.4 1.6 0.2 0.1 0.0 0.0 1.1 0.4 14.8 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 1.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 3.3 0.4 0.0 0.0 0.1 2.8 6.9 3.3 4.5 2.2 2.9 6.0 5.1 4.8 2.0 4.0 11.0 88.8 0.0 0.5 26.1 2.7 66.9 14.9 31.2 82.0 1.4 5.4 14.7 11.8 0.0 7.2 1.8 22.9 3.1 3.0 3.0 0.0 0.3 0.4 5.1 10.1 28.5 51.9 0.4 6.9 1.8 5.9 19.2 1.5 5.3 5.7 0.2 21.4 0.2 1.3 0.0 6.4 80.3 16.2 4.8 6.6 1.9 0.3 2.7 7.2 4.7 0.2 1.1 0.0 28.6 26.7 0.7 2.5 1.2 0.3 4.8 2.5 0.1 9.0 0.6 13.1 12.3 8.2 0.5 2.0 8.5 12.8 3.7 4.7 0.1 3.6 1.1 DLL4 ENSG00000128917 "Delta like canonical Notch ligand 4" Q9NR61 15 40929340-40939073 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Angiogenesis, Differentiation, Neurogenesis, Notch signaling pathway, Sensory transduction, Vision" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 70.7;Distal enterocytes: 24.2;Endothelial cells: 48.6;Hepatic stellate cells: 30.4;Intestinal goblet cells: 36.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "BJ hTERT+: 59.4;HUVEC TERT2: 15.7;SCLC-21H: 32.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA023392 Uncertain NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA023392: AB_1847740" "unprognostic (1.92e-2)" "prognostic unfavorable (3.97e-4)" "unprognostic (7.52e-2)" "unprognostic (4.71e-2)" "unprognostic (2.72e-1)" "unprognostic (4.16e-2)" "unprognostic (3.56e-2)" "unprognostic (1.60e-2)" "unprognostic (2.49e-1)" "unprognostic (2.73e-1)" "unprognostic (3.51e-2)" "unprognostic (6.10e-2)" "unprognostic (2.56e-3)" "unprognostic (9.92e-2)" "unprognostic (2.93e-1)" "unprognostic (1.51e-2)" "unprognostic (5.51e-3)" 25.2 2.6 6.9 2.9 6.1 0.3 21.2 6.5 7.0 8.0 4.9 7.6 4.0 8.8 1.0 3.7 7.6 3.7 23.8 5.8 6.0 10.0 3.5 22.5 5.0 7.1 6.5 4.1 2.9 2.9 5.6 19.8 7.5 7.9 3.0 0.9 4.3 2.7 10.0 5.5 6.8 4.2 6.6 4.6 4.8 1.5 8.4 5.0 15.4 10.6 1.7 8.7 7.6 6.2 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.9 59.4 0.2 0.3 0.5 0.0 0.0 0.9 0.0 0.0 0.0 0.8 0.0 0.1 0.0 1.0 0.5 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 15.7 0.0 0.4 1.1 0.1 0.1 0.0 0.6 0.0 0.9 0.0 1.4 0.5 1.6 0.0 0.1 32.5 0.0 0.3 0.7 0.0 0.0 0.0 3.5 0.9 0.0 0.1 0.0 0.0 1.3 0.4 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 6.1 6.5 7.0 5.8 6.0 7.1 6.5 7.5 6.6 8.4 6.2 70.7 0.0 2.7 0.0 1.7 1.3 0.2 0.2 4.0 4.9 1.6 2.8 3.2 1.5 0.9 0.0 0.0 1.5 0.2 24.2 0.0 0.2 0.2 1.9 0.7 48.6 17.4 0.0 0.9 0.2 0.6 3.1 13.3 2.6 2.5 0.0 30.4 0.1 0.2 0.0 0.6 36.3 6.1 1.6 0.8 0.3 0.0 0.8 1.8 11.2 0.0 0.2 0.0 0.5 0.5 0.2 16.7 0.0 3.5 2.3 9.2 0.0 0.2 1.4 0.0 0.9 3.8 0.8 2.0 1.0 1.6 1.9 0.4 0.4 12.0 0.6 DMAC1 "C9orf123, MGC4730, TMEM261" ENSG00000137038 "Distal membrane arm assembly complex 1" Q96GE9 9 7796500-7888380 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 500.8;Hofbauer cells: 221.7;Proximal tubular cells: 254.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA014585 Approved NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 36: HEL - Hemostasis" "Cluster 7: Non-specific - Mitochondria" "HPA014585: AB_1845803" "unprognostic (1.48e-2)" "unprognostic (3.74e-2)" "unprognostic (7.23e-3)" "prognostic favorable (4.15e-4)" "unprognostic (2.78e-2)" "unprognostic (2.79e-3)" "unprognostic (1.33e-1)" "unprognostic (1.28e-1)" "unprognostic (1.38e-1)" "unprognostic (1.23e-2)" "unprognostic (3.26e-3)" "unprognostic (3.65e-1)" "prognostic favorable (1.96e-11)" "unprognostic (1.75e-1)" "unprognostic (4.19e-1)" "unprognostic (2.35e-1)" "unprognostic (7.41e-2)" 10.6 11.9 16.8 7.7 17.0 6.2 12.4 17.5 21.0 9.3 9.0 12.6 9.8 10.0 11.8 9.3 11.0 6.3 25.4 16.3 17.8 15.9 10.2 7.2 10.0 15.2 15.0 13.2 9.2 21.8 12.3 8.1 15.6 11.9 9.9 9.0 14.3 11.6 43.1 8.5 9.1 8.1 15.1 10.4 10.7 7.0 16.0 20.6 11.8 29.8 8.9 11.5 8.3 16.9 18.5 21.8 19.7 12.3 15.4 19.1 13.3 11.0 7.7 11.5 10.4 9.9 11.3 27.1 5.6 9.8 15.0 9.8 21.2 18.8 11.6 16.2 24.3 49.3 32.7 31.8 15.6 17.2 6.7 24.1 13.2 9.1 13.9 10.6 11.0 24.3 9.2 5.6 12.2 15.7 25.1 39.7 17.5 15.6 10.5 19.0 11.1 16.4 13.2 17.6 31.5 17.6 12.0 8.0 14.1 13.5 10.5 10.5 14.0 8.8 14.2 11.6 7.7 7.0 12.0 14.5 7.4 14.3 9.0 2.0 10.1 4.5 11.5 12.2 17.4 26.5 15.7 12.3 12.6 22.5 20.5 16.5 1.6 20.8 9.8 13.1 19.9 19.6 16.8 17.0 17.5 21.0 16.3 17.8 15.2 15.0 15.6 15.1 16.0 16.9 42.2 70.5 48.5 0.0 15.7 0.0 0.0 0.0 0.0 0.0 69.5 81.5 0.0 0.0 24.1 101.2 0.0 113.6 13.9 0.0 500.8 94.2 0.0 81.4 64.3 30.0 0.0 0.0 0.0 90.7 96.3 32.8 0.0 58.6 27.8 127.7 0.0 0.0 221.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.4 0.0 0.0 25.8 0.0 0.0 0.0 0.0 62.4 0.0 0.0 3.1 0.0 0.0 254.7 70.7 0.0 0.0 0.0 29.6 0.0 0.0 0.0 0.0 55.4 17.3 79.3 0.0 0.0 DNAH12 "DHC3, DLP12, DNAH12L, DNAH7L, Dnahc3, DNHD2, FLJ40427, FLJ44290, hdhc3, HL-19" ENSG00000174844 "Dynein axonemal heavy chain 12" Q6ZR08 3 57293699-57544344 "Cancer-related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Motor protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 5.0;choroid plexus: 7.1;fallopian tube: 10.3;lung: 3.5;testis: 8.9" "Group enriched" "Detected in many" 5 "Endometrial ciliated cells: 230.5;Respiratory ciliated cells: 318.9" "Cancer enhanced" "Detected in single" "endometrial cancer: 0.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in many" "midbrain: 9.6" "HPA037493, HPA058203, HPA061365" Enhanced NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 49: Ciliated cells - Cilium organization" "HPA037493: AB_10671758, HPA058203: AB_2683637, HPA061365: AB_2684493" "unprognostic (4.85e-2)" "unprognostic (1.29e-2)" "unprognostic (2.23e-1)" "unprognostic (2.18e-3)" "unprognostic (2.96e-2)" "unprognostic (2.17e-1)" "unprognostic (2.80e-2)" "unprognostic (1.51e-3)" "unprognostic (3.06e-2)" "unprognostic (3.21e-1)" "unprognostic (4.40e-2)" "unprognostic (5.90e-2)" "unprognostic (3.43e-5)" "unprognostic (2.82e-2)" "unprognostic (1.34e-1)" "unprognostic (2.53e-2)" "unprognostic (5.47e-2)" 0.0 0.2 1.2 0.0 1.0 0.0 0.2 0.7 0.7 0.9 7.1 0.0 0.0 0.3 0.1 0.0 10.3 0.2 0.0 1.3 1.3 0.1 0.1 3.5 0.0 4.5 5.0 0.1 0.7 0.0 0.9 0.0 2.9 0.1 0.0 0.3 0.1 0.1 0.0 0.1 0.0 0.0 2.8 0.0 0.1 8.9 1.2 0.0 0.1 0.0 0.0 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 1.0 0.7 0.7 1.3 1.3 4.5 5.0 2.9 2.8 1.2 1.6 0.2 3.2 1.1 13.7 0.2 0.0 0.2 5.4 0.0 0.3 0.8 0.6 1.1 0.0 42.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 49.8 230.5 1.3 0.1 1.8 0.0 3.9 0.0 0.0 1.2 0.0 4.6 1.3 0.3 0.0 0.0 0.1 0.0 3.8 0.0 6.1 0.0 0.0 9.8 0.9 0.7 0.0 2.8 0.1 1.7 0.0 5.0 15.8 0.1 0.0 0.4 0.0 0.1 0.0 0.5 318.9 0.2 0.0 0.7 1.6 28.4 2.7 0.0 0.0 0.0 0.5 5.4 0.1 0.1 DNAH5 "CILD3, Dnahc5, HL1, KTGNR, PCD" ENSG00000039139 "Dynein axonemal heavy chain 5" Q8TE73 5 13690328-14011818 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Motor protein" "Ciliopathy, Disease variant, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.7;choroid plexus: 14.0" "Cell type enhanced" "Detected in many" "Club cells: 61.7;Endometrial ciliated cells: 190.3;Respiratory ciliated cells: 258.7" "Cancer enhanced" "Detected in many" "prostate cancer: 3.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 1.6;LHCN-M2: 1.1;PC-3: 2.7;RPTEC TERT1: 1.3;TIME: 1.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA037469, HPA037470" Enhanced NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 49: Ciliated cells - Cilium organization" "HPA037469: AB_10672791, HPA037470: AB_10672348" "unprognostic (3.85e-1)" "unprognostic (8.17e-2)" "unprognostic (5.94e-2)" "unprognostic (1.12e-1)" "unprognostic (4.58e-3)" "unprognostic (6.23e-2)" "unprognostic (3.33e-3)" "unprognostic (2.86e-2)" "unprognostic (9.94e-2)" "unprognostic (4.39e-2)" "unprognostic (1.59e-1)" "unprognostic (9.99e-2)" "unprognostic (9.97e-3)" "unprognostic (8.87e-2)" "unprognostic (8.72e-2)" "unprognostic (2.82e-2)" "unprognostic (1.65e-1)" 0.0 0.1 0.9 0.0 1.1 0.0 1.5 0.5 0.3 0.3 14.0 0.1 0.0 0.1 0.1 0.0 3.8 0.1 0.0 1.0 1.7 0.8 1.0 1.7 0.0 4.2 6.7 0.0 0.9 0.0 2.0 0.0 4.0 1.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 2.1 0.0 0.4 0.3 1.8 0.0 1.1 0.0 0.0 0.8 0.0 1.4 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.4 1.6 0.0 0.1 0.0 0.5 0.0 0.5 0.2 0.4 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 2.7 0.0 0.0 0.0 1.3 0.4 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.1 0.5 0.3 1.0 1.7 4.2 6.7 4.0 2.1 1.8 1.4 0.3 3.2 24.4 7.2 0.2 0.0 1.7 5.6 0.0 0.0 11.7 7.0 1.5 14.3 61.7 5.5 0.0 0.0 0.1 0.0 0.0 6.7 7.3 190.3 1.9 1.2 1.8 0.0 12.9 3.6 0.2 1.8 0.0 12.4 2.5 0.0 0.0 10.9 0.0 0.0 7.8 0.0 6.1 0.0 0.0 5.0 0.0 0.5 0.0 0.0 0.0 0.5 0.0 4.0 0.4 2.6 0.0 0.0 0.1 14.8 0.0 4.3 258.7 0.0 0.0 1.6 2.6 2.6 3.6 0.0 0.0 0.0 0.4 0.1 0.0 3.8 DNAH7 KIAA0944 ENSG00000118997 "Dynein axonemal heavy chain 7" Q8WXX0 2 195737703-196068837 "Plasma proteins, Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 12.9;choroid plexus: 29.8" "Cell type enhanced" "Detected in many" "Astrocytes: 197.2;Cone photoreceptor cells: 70.9;Early spermatids: 59.3;Endometrial ciliated cells: 103.5;Excitatory neurons: 93.0;Respiratory ciliated cells: 139.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "PC-3: 5.9;RPTEC TERT1: 2.8" "Region enhanced" "Detected in many" "midbrain: 4.4" "HPA034724, HPA044070" Enhanced Supported Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "HPA034724: AB_10670977, HPA044070: AB_2678798" "unprognostic (1.71e-1)" "unprognostic (2.81e-2)" "unprognostic (2.65e-2)" "unprognostic (1.04e-2)" "unprognostic (3.56e-1)" "unprognostic (1.58e-2)" "unprognostic (6.74e-3)" "unprognostic (2.24e-1)" "unprognostic (1.71e-1)" "unprognostic (1.63e-1)" "unprognostic (2.84e-2)" "unprognostic (1.71e-1)" "unprognostic (6.25e-3)" "unprognostic (2.24e-1)" "unprognostic (7.76e-2)" "unprognostic (2.52e-3)" "unprognostic (3.98e-2)" 0.3 1.0 8.2 0.2 7.9 0.0 0.6 3.6 10.1 2.5 29.8 0.7 0.1 0.8 1.7 0.2 9.8 0.6 0.4 8.0 7.1 3.4 0.3 2.3 0.1 10.2 12.9 0.5 2.6 2.0 7.2 0.1 8.0 1.1 0.5 8.9 0.8 0.9 0.0 0.2 0.7 0.3 7.6 0.1 0.6 10.8 9.0 0.1 3.2 0.0 0.2 0.2 0.3 6.7 0.3 1.3 0.3 0.1 0.7 0.4 0.1 0.1 0.8 0.3 0.3 0.2 1.0 0.0 0.3 0.3 1.0 0.0 0.0 0.2 0.2 0.0 0.8 0.0 1.7 0.4 0.1 0.0 0.1 0.2 0.2 1.1 0.2 1.7 0.0 0.0 0.3 1.8 0.5 1.4 0.0 0.0 0.3 0.7 5.9 0.0 0.3 0.5 2.8 0.2 0.6 1.0 0.3 0.2 0.1 0.1 0.5 0.1 0.0 0.7 0.2 1.1 0.3 1.4 1.4 0.0 1.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 8.2 7.9 3.6 10.1 8.0 7.1 10.2 12.9 8.0 7.6 9.0 6.7 0.5 0.0 6.1 197.2 0.0 0.9 1.2 3.3 0.0 1.9 2.1 1.3 1.3 0.0 12.3 1.8 70.9 0.0 0.1 4.4 0.0 2.9 59.3 103.5 2.8 1.8 0.0 0.0 93.0 0.7 0.0 1.0 1.5 3.0 0.0 0.8 0.7 0.0 0.1 1.7 25.6 1.0 4.1 0.0 1.2 27.8 0.6 0.4 1.8 13.1 0.0 2.9 0.0 5.5 2.2 0.6 0.2 1.5 0.1 1.8 3.7 2.6 139.5 36.8 0.0 2.1 1.1 28.0 5.7 0.0 1.3 0.1 0.2 0.8 0.7 0.7 DNAH8 hdhc9 ENSG00000124721 "Dynein axonemal heavy chain 8" Q96JB1 6 38715311-39030792 "Plasma proteins, Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 2.6;prostate: 2.1;testis: 7.8" "Group enriched" "Detected in some" 4 "Early spermatids: 35.4;Late spermatids: 13.2;Spermatocytes: 33.3" "Cancer enriched" "Detected in single" 7 "prostate cancer: 2.5" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 8 "basophil: 2.5" "Lineage enriched" "Detected in single" 8 "granulocytes: 2.5" "Cell line enriched" "Detected in some" 8 "HMC-1: 47.1" "Not detected" "Not detected" HPA028447 Uncertain NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 68: Epididymis - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA028447: AB_10599600" "unprognostic (2.83e-1)" "unprognostic (4.46e-4)" "unprognostic (1.27e-1)" "unprognostic (5.24e-2)" "unprognostic (1.23e-1)" "unprognostic (2.00e-3)" "unprognostic (1.02e-1)" "unprognostic (1.22e-2)" "unprognostic (1.41e-1)" "unprognostic (3.47e-3)" "unprognostic (1.19e-1)" "unprognostic (1.39e-1)" "unprognostic (2.17e-9)" "unprognostic (1.46e-3)" "unprognostic (1.56e-1)" "unprognostic (1.62e-1)" "unprognostic (1.48e-3)" 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 2.1 0.0 0.0 0.0 0.1 0.0 1.6 0.1 0.0 0.0 0.9 0.1 7.8 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 47.1 0.0 0.0 0.0 0.0 0.0 5.9 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.7 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.9 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 35.4 0.0 0.0 0.2 0.0 0.0 2.7 0.0 0.1 0.2 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 13.2 1.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 1.7 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.1 33.3 5.7 0.0 0.0 0.0 0.6 0.0 0.0 0.0 DNAI1 "CILD1, DIC1, PCD" ENSG00000122735 "Dynein axonemal intermediate chain 1" Q9UI46 9 34457414-34520988 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Motor protein" "Ciliopathy, Disease variant, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 9.9;choroid plexus: 28.3;fallopian tube: 33.9;pituitary gland: 9.5;testis: 33.5" "Cell type enhanced" "Detected in some" "Early spermatids: 29.6;Endometrial ciliated cells: 48.8;Late spermatids: 35.0;Respiratory ciliated cells: 132.2;Spermatocytes: 56.0" "Cancer enhanced" "Detected in many" "endometrial cancer: 3.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.0;HDLM-2: 1.4;SK-BR-3: 1.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA021649, HPA021843" Enhanced NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 28: BEWO - Transcription regulation" "Cluster 49: Ciliated cells - Cilium organization" "HPA021649: AB_1847913, HPA021843: AB_1847914" "unprognostic (9.61e-2)" "unprognostic (5.16e-2)" "unprognostic (4.59e-2)" "unprognostic (1.44e-3)" "unprognostic (3.72e-1)" "unprognostic (1.01e-1)" "unprognostic (1.92e-1)" "unprognostic (6.39e-2)" "unprognostic (4.38e-1)" "unprognostic (1.51e-1)" "unprognostic (8.16e-3)" "unprognostic (8.14e-2)" "unprognostic (2.74e-2)" "unprognostic (3.77e-2)" "unprognostic (2.94e-1)" "unprognostic (1.35e-1)" "unprognostic (1.13e-1)" 0.0 0.0 2.7 0.0 3.2 0.0 0.5 2.3 2.5 2.2 28.3 0.0 0.0 0.9 0.2 0.0 33.9 0.1 0.1 2.8 3.1 1.3 0.1 4.5 0.0 7.3 9.9 0.1 0.9 1.2 9.5 0.0 4.8 0.2 0.0 2.7 0.0 0.1 0.1 0.0 0.0 0.0 5.5 0.0 0.2 33.5 3.2 0.0 0.2 0.0 0.0 0.0 0.0 2.4 0.1 0.0 0.6 0.2 0.0 0.0 2.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.1 0.0 1.0 0.2 0.4 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 3.2 2.3 2.5 2.8 3.1 7.3 9.9 4.8 5.5 3.2 2.4 0.0 0.0 0.5 3.9 0.1 0.0 0.0 5.0 0.0 0.0 0.5 0.3 0.4 0.0 11.0 0.0 4.2 0.2 0.0 0.0 1.9 0.0 29.6 48.8 0.5 0.2 0.0 0.0 9.4 0.0 0.1 0.3 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 16.2 0.0 2.0 0.0 0.0 35.0 0.3 0.2 0.0 1.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.5 0.0 0.1 0.0 0.4 132.2 1.3 0.0 0.0 1.4 56.0 2.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 DNAI4 "DIC4, FLJ23129, WDR78" ENSG00000152763 "Dynein axonemal intermediate chain 4" Q5VTH9 1 66812885-66924856 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 27.7;testis: 35.2" "Cell type enriched" "Detected in some" 5 "Cardiomyocytes: 8.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "NK-cell: 3.8" "Lineage enriched" "Detected in single" 4 "NK-cells: 3.8" "Cell line enhanced" "Detected in many" "ASC TERT1: 7.0;RPTEC TERT1: 11.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 43: Cardiomyocytes - Nuclear processes" "unprognostic (4.26e-2)" "unprognostic (4.04e-1)" "unprognostic (1.58e-3)" "unprognostic (2.19e-2)" "unprognostic (1.85e-1)" "unprognostic (1.71e-2)" "unprognostic (1.74e-1)" "unprognostic (1.01e-1)" "unprognostic (8.19e-2)" "unprognostic (4.00e-1)" "unprognostic (1.68e-3)" "unprognostic (2.08e-2)" "prognostic favorable (9.60e-5)" "unprognostic (1.98e-1)" "unprognostic (5.79e-2)" "unprognostic (5.03e-2)" "unprognostic (1.69e-1)" 1.5 1.7 3.3 0.5 3.0 0.1 3.0 2.0 1.8 4.0 19.4 5.4 0.7 3.0 5.0 0.5 27.7 2.5 1.2 2.6 4.1 6.3 1.2 4.2 1.0 12.6 10.2 3.0 1.4 7.0 2.8 2.1 7.4 1.8 4.1 4.1 1.1 2.0 0.5 1.0 0.6 1.3 9.5 0.9 0.8 35.2 3.8 2.3 5.9 0.3 0.7 0.9 0.9 8.6 2.9 1.2 1.6 2.1 4.8 7.0 0.6 1.3 2.2 1.6 1.7 0.3 2.4 1.5 0.3 1.3 5.0 0.2 1.1 0.3 2.5 0.2 0.4 0.4 0.7 0.2 1.6 0.1 0.0 3.3 3.5 6.0 1.2 5.8 0.6 1.5 0.4 0.1 2.8 1.1 0.7 0.5 2.1 1.0 0.6 0.7 0.0 0.0 11.4 0.0 1.9 0.9 1.4 0.5 1.1 1.7 0.5 1.0 0.2 0.7 0.0 4.7 0.7 0.5 0.0 3.2 1.4 0.3 1.7 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.3 0.1 0.0 0.9 0.5 0.2 0.1 3.8 0.0 0.0 0.1 0.1 3.3 3.0 2.0 1.8 2.6 4.1 12.6 10.2 7.4 9.5 3.8 8.6 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 1.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.5 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 DNAJA4 PRO1472 ENSG00000140403 "DnaJ heat shock protein family (Hsp40) member A4" Q8WW22 15 78264086-78282196 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 138.4;tongue: 144.6" "Group enriched" "Detected in many" 5 "Early spermatids: 673.9;Late spermatids: 1608.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 33.6;CAPAN-2: 43.3;HeLa: 47.3;MCF7: 33.6;RT4: 85.2;SCLC-21H: 53.3;SiHa: 42.7;THP-1: 39.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004646, HPA041790" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 15: RT4 - Unknown function" "Cluster 34: Spermatids - Unknown function" "Plasma membrane, Cytosol" "CAB004646: AB_426011, HPA041790: AB_2677674" "unprognostic (8.41e-2)" "unprognostic (2.48e-1)" "unprognostic (3.00e-2)" "unprognostic (8.20e-3)" "unprognostic (1.14e-3)" "unprognostic (1.99e-1)" "unprognostic (2.28e-2)" "unprognostic (2.46e-1)" "unprognostic (5.86e-2)" "unprognostic (7.78e-2)" "unprognostic (2.31e-2)" "unprognostic (1.28e-1)" "prognostic favorable (1.08e-7)" "unprognostic (1.89e-1)" "unprognostic (2.84e-1)" "unprognostic (9.01e-2)" "unprognostic (2.93e-2)" 16.5 20.0 60.6 14.0 67.7 63.7 12.6 62.6 138.4 14.1 45.6 18.0 13.8 8.3 20.2 15.8 38.9 11.2 123.3 68.6 93.1 26.7 3.3 19.7 11.3 65.7 73.3 12.1 6.6 7.4 30.9 9.5 89.8 26.7 18.5 33.0 15.6 15.6 123.2 28.6 16.3 19.6 59.8 13.5 24.2 78.3 73.5 9.4 9.6 144.6 12.4 29.6 13.6 71.3 33.6 0.2 0.0 0.0 0.0 0.0 0.1 4.1 0.0 1.1 0.5 0.0 43.3 0.0 0.3 3.2 0.0 31.3 0.0 0.0 0.1 0.1 0.0 19.9 47.3 0.0 9.4 0.0 20.6 3.6 4.1 2.6 0.0 0.0 6.6 0.0 0.0 0.0 0.4 33.6 0.0 0.0 0.0 14.4 0.3 0.0 0.0 0.0 0.1 85.2 53.3 0.0 42.7 8.6 3.6 2.3 32.4 39.8 0.5 0.0 8.7 4.0 0.4 0.6 2.4 0.0 0.1 4.2 0.0 0.0 0.3 1.1 0.6 0.3 1.0 0.7 0.9 0.9 0.4 0.1 1.7 1.4 0.0 0.1 0.4 0.2 0.5 0.6 60.6 67.7 62.6 138.4 68.6 93.1 65.7 73.3 89.8 59.8 73.5 71.3 41.9 6.4 4.8 12.7 10.0 28.8 209.9 14.0 2.2 19.6 44.6 29.2 43.6 2.8 33.5 7.3 81.3 1.9 6.7 55.5 1.9 1.3 673.9 124.0 11.4 18.9 100.3 92.8 16.6 2.4 3.8 18.3 21.4 41.8 36.9 7.5 6.8 0.2 16.5 6.7 24.0 34.9 10.2 9.5 81.7 1608.0 10.2 51.7 51.6 6.5 3.5 10.3 6.2 15.1 19.0 5.1 55.3 11.3 3.7 115.8 15.8 7.2 138.9 22.6 6.6 17.4 20.2 33.8 27.7 16.9 46.7 6.8 37.1 6.9 42.1 190.1 DNAJB7 HSC3 ENSG00000172404 "DnaJ heat shock protein family (Hsp40) member B7" Q7Z6W7 22 40859549-40862113 "Predicted intracellular proteins" Chaperone "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 12 "testis: 10.4" "Cell type enriched" "Detected in some" 5 "Early spermatids: 553.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA000534 Approved NA NA "Cluster 46: Basophils - DNA binding" "Cluster 78: Testis - Spermatogenesis" "Cluster 29: Early spermatids - Spermatogenesis" "HPA000534: AB_1078693" "unprognostic (3.89e-2)" "unprognostic (1.12e-2)" "unprognostic (9.61e-2)" "unprognostic (1.27e-1)" "unprognostic (5.45e-2)" "unprognostic (2.66e-2)" "unprognostic (1.16e-2)" "unprognostic (5.56e-3)" "unprognostic (1.62e-1)" "unprognostic (7.42e-2)" "unprognostic (1.22e-3)" "unprognostic (2.81e-2)" "unprognostic (4.46e-4)" "unprognostic (3.32e-3)" "unprognostic (3.06e-2)" "unprognostic (7.05e-2)" "unprognostic (2.45e-2)" 0.1 0.1 0.1 0.1 0.2 0.5 0.1 0.8 0.7 0.2 0.4 0.1 0.4 0.2 0.0 0.1 0.2 0.1 0.0 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.3 0.2 0.0 0.2 0.0 0.2 0.2 0.1 0.8 0.2 0.0 0.4 0.1 0.5 0.0 0.0 0.1 0.1 10.4 0.2 0.0 0.3 0.0 0.0 0.1 0.1 0.7 0.0 0.0 0.2 0.3 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.4 0.0 0.1 0.4 0.4 0.2 0.1 0.0 0.2 0.2 0.1 0.0 0.1 0.3 0.1 0.1 0.1 0.0 0.2 0.0 0.2 0.0 0.2 0.3 0.3 0.1 0.3 0.2 0.2 0.0 0.1 0.3 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.4 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.8 0.7 0.2 0.1 0.1 0.1 0.2 0.0 0.2 0.7 0.0 0.0 0.0 0.3 0.2 0.0 0.1 0.0 0.0 3.4 0.0 0.1 0.0 0.0 0.0 0.0 4.2 0.1 0.4 0.8 0.0 0.0 553.5 1.5 0.8 0.4 0.0 0.0 0.5 0.0 0.1 0.1 0.0 0.4 4.5 0.2 0.0 0.0 0.1 1.7 0.5 0.4 0.0 0.0 0.0 98.5 2.8 0.2 0.0 0.0 0.0 0.9 0.0 1.0 0.7 0.0 0.0 2.6 0.1 0.1 6.0 0.0 0.0 11.2 0.0 0.3 0.1 2.9 1.5 0.0 0.0 0.3 0.2 0.2 0.9 0.1 DNAJB9 MDG1 ENSG00000128590 "DnaJ heat shock protein family (Hsp40) member B9" Q9UBS3 7 108569867-108574850 "Predicted intracellular proteins" "Unfolded protein response" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 350.9;Plasma cells: 409.3;Syncytiotrophoblasts: 569.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HHSteC: 116.5;Karpas-707: 109.3;U-266/70: 191.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040967, HPA041553" Supported Approved "Endoplasmic reticulum,Cytosol" "Intracellular and membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum, Cytosol" "HPA040967: AB_10794430, HPA041553: AB_10794300" "unprognostic (1.08e-1)" "unprognostic (1.03e-1)" "unprognostic (1.32e-1)" "unprognostic (4.75e-3)" "unprognostic (5.63e-2)" "unprognostic (1.96e-1)" "unprognostic (5.37e-2)" "unprognostic (5.13e-2)" "unprognostic (3.16e-2)" "unprognostic (1.89e-1)" "unprognostic (1.76e-1)" "unprognostic (1.05e-1)" "unprognostic (2.68e-3)" "unprognostic (1.91e-1)" "unprognostic (1.50e-1)" "unprognostic (1.51e-1)" "unprognostic (8.76e-2)" 21.9 58.4 16.2 21.5 17.1 40.8 29.9 18.0 22.5 34.8 27.0 20.6 23.4 23.9 62.8 13.3 19.4 22.3 45.3 16.8 23.5 63.2 103.8 21.4 21.1 18.8 21.3 27.9 71.6 21.4 43.5 41.6 20.8 28.4 19.4 23.1 41.7 44.6 34.8 10.9 20.7 21.9 19.6 17.6 25.7 33.7 18.5 15.9 77.8 26.3 31.1 28.9 11.5 20.0 9.4 10.6 14.2 16.3 38.6 27.6 31.2 33.6 40.8 18.2 21.8 10.7 17.5 12.4 36.6 10.7 56.6 11.2 16.0 8.3 18.7 13.2 8.7 6.6 7.2 33.0 116.5 9.8 12.3 19.5 63.2 10.8 58.6 41.1 19.3 7.0 9.7 109.3 29.0 14.0 9.3 11.5 14.2 11.0 5.9 6.0 14.3 65.8 15.1 6.1 9.8 20.5 12.4 55.7 65.2 39.4 10.4 13.6 22.4 19.1 9.0 24.0 11.8 191.8 66.0 14.0 16.8 12.7 17.6 75.9 19.3 9.4 34.1 15.0 59.0 24.5 36.2 34.2 14.3 21.2 20.2 23.5 5.3 26.0 17.0 78.1 22.6 30.3 16.2 17.1 18.0 22.5 16.8 23.5 18.8 21.3 20.8 19.6 18.5 20.0 65.7 3.2 28.8 10.1 110.3 185.6 102.4 123.1 71.7 40.3 129.4 58.9 65.6 44.3 75.1 53.3 8.4 106.7 95.0 28.0 49.0 47.5 350.9 46.1 38.1 55.3 66.6 44.9 14.5 45.7 123.0 121.2 51.0 92.5 92.1 16.2 33.5 185.9 40.1 20.2 15.6 76.8 69.2 37.8 190.5 211.4 38.2 60.2 339.7 11.2 16.0 90.4 23.7 8.5 11.2 33.0 32.3 46.3 409.3 144.7 31.3 155.6 35.4 33.3 39.5 49.4 129.0 157.0 89.9 39.4 158.7 569.4 115.1 18.6 28.8 79.5 DNAJC15 "DNAJD1, MCJ" ENSG00000120675 "DnaJ heat shock protein family (Hsp40) member C15" Q9Y5T4 13 43023203-43114213 "Disease related genes, Predicted membrane proteins" "Protein transport, Translocation, Transport" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 462.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 44: Endometrium - Transcription" "unprognostic (1.12e-1)" "unprognostic (2.89e-2)" "unprognostic (1.09e-2)" "unprognostic (2.97e-2)" "unprognostic (1.53e-2)" "unprognostic (3.07e-3)" "unprognostic (3.91e-2)" "unprognostic (1.49e-1)" "unprognostic (1.25e-1)" "unprognostic (3.23e-1)" "unprognostic (2.38e-2)" "unprognostic (3.40e-1)" "unprognostic (2.50e-1)" "unprognostic (2.51e-2)" "unprognostic (2.90e-1)" "unprognostic (5.92e-3)" "unprognostic (3.17e-1)" 5.2 7.2 13.1 5.2 13.3 3.8 5.0 13.6 23.0 6.1 9.4 7.7 8.8 3.2 1.5 4.6 3.2 4.0 10.8 12.1 14.8 9.3 7.0 5.3 6.5 14.2 13.5 1.0 4.0 6.8 3.2 5.5 14.3 3.1 6.4 4.8 4.3 8.5 6.9 3.5 8.4 4.5 16.1 4.1 4.7 3.9 15.4 5.8 6.7 6.8 5.9 4.2 2.3 15.5 0.0 0.0 2.6 2.3 9.3 13.9 1.9 10.7 10.4 12.6 6.7 12.8 11.1 8.2 0.0 13.5 6.3 7.8 1.2 9.2 13.3 17.7 0.0 7.8 5.5 9.2 10.7 0.0 5.4 14.0 17.6 6.3 6.0 6.4 10.2 4.8 0.0 1.4 10.4 4.5 0.1 2.0 0.0 9.5 0.0 3.0 2.5 12.2 19.8 4.1 3.3 3.8 0.0 5.8 8.2 4.3 4.2 11.1 10.8 5.1 2.3 8.5 2.8 0.5 1.4 0.0 11.0 0.0 5.0 5.8 4.4 2.3 2.8 4.9 2.6 5.7 3.5 3.3 8.2 4.6 2.7 3.1 0.3 3.9 4.0 5.2 4.9 3.0 13.1 13.3 13.6 23.0 12.1 14.8 14.2 13.5 14.3 16.1 15.4 15.5 82.2 83.3 49.0 16.6 111.2 42.3 23.0 59.2 53.5 25.9 73.2 80.9 166.4 100.1 71.7 132.4 25.0 76.9 58.4 192.9 115.4 271.7 462.8 172.3 77.8 83.1 133.7 98.7 16.6 329.0 291.3 72.5 63.2 289.2 39.2 13.9 71.7 238.5 140.3 30.3 22.4 147.2 63.1 143.8 104.3 124.8 15.2 130.5 88.9 22.5 159.3 50.8 64.9 25.6 17.3 274.7 241.3 12.0 148.1 20.5 263.3 342.9 72.4 26.2 26.3 71.4 92.8 279.4 117.8 90.6 45.6 92.6 70.2 16.2 176.3 38.8 DNAJC28 "C21orf55, C21orf78" ENSG00000177692 "DnaJ heat shock protein family (Hsp40) member C28" Q9NX36 21 33485530-33491716 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 7.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 14.0;Early spermatids: 33.3;Proximal tubular cells: 10.4;Spermatocytes: 13.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 3.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018003, HPA030076" Approved NA NA "Cluster 23: Testis - Cell cycle regulation" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA018003: AB_1845695, HPA030076: AB_10602218" "unprognostic (9.63e-3)" "unprognostic (4.44e-1)" "unprognostic (5.66e-3)" "unprognostic (2.05e-1)" "unprognostic (4.00e-2)" "unprognostic (4.92e-3)" "unprognostic (2.89e-2)" "unprognostic (6.61e-3)" "unprognostic (1.45e-1)" "unprognostic (7.23e-4)" "unprognostic (1.20e-3)" "unprognostic (1.04e-1)" "unprognostic (3.14e-9)" "unprognostic (1.84e-1)" "unprognostic (1.71e-1)" "unprognostic (4.53e-2)" "unprognostic (1.24e-2)" 0.6 2.2 0.8 0.1 0.8 0.4 0.7 0.9 1.2 0.5 0.7 1.1 0.3 0.5 1.2 1.1 0.3 0.5 2.9 0.8 0.7 2.6 2.6 0.6 0.2 0.8 0.7 0.4 1.3 1.4 1.5 0.5 0.8 0.8 0.7 1.7 1.4 0.6 2.8 0.6 1.1 0.3 0.5 1.2 1.5 7.0 0.8 0.1 2.5 2.0 0.1 0.7 0.6 0.9 0.3 0.1 1.2 0.4 3.1 0.8 0.3 0.6 0.6 1.2 0.5 0.1 0.5 0.3 0.1 0.0 0.6 0.1 0.1 0.1 0.3 0.1 1.3 0.7 0.2 0.8 0.7 0.0 1.2 0.6 0.6 0.6 0.1 1.0 0.7 0.6 0.4 0.1 0.4 0.4 0.1 0.3 0.6 0.4 0.0 0.3 1.3 0.1 0.6 0.1 0.9 0.6 0.1 0.0 0.3 0.4 1.1 0.2 0.2 0.5 0.2 0.1 0.1 0.5 0.5 0.1 1.1 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.8 0.8 0.9 1.2 0.8 0.7 0.8 0.7 0.8 0.5 0.8 0.9 1.3 0.0 2.2 0.3 0.7 0.4 0.3 1.1 1.8 1.7 1.2 0.9 14.0 1.5 0.5 3.7 0.0 1.3 0.9 1.3 3.9 2.2 33.3 0.7 0.8 1.4 1.2 4.0 2.5 1.3 0.4 1.1 1.1 0.9 3.8 0.8 1.4 4.7 1.0 1.7 2.3 1.1 0.0 2.4 0.3 7.6 0.6 0.9 0.0 1.9 1.3 0.9 0.0 1.0 1.2 1.7 1.2 1.2 2.0 0.6 1.8 10.4 2.4 2.2 0.0 1.1 1.2 13.4 2.0 0.6 0.0 2.3 0.8 3.0 0.6 0.2 DNPEP "ASPEP, DAP" ENSG00000123992 "Aspartyl aminopeptidase" Q9ULA0 2 219372043-219400022 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 364.4;Late spermatids: 462.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036398, HPA044860" Enhanced Supported Cytosol NA NA 2700000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 28: BEWO - Transcription regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "HPA036398: AB_10970915, HPA044860: AB_10961275" "unprognostic (3.71e-1)" "unprognostic (6.45e-2)" "unprognostic (1.26e-1)" "unprognostic (1.05e-2)" "unprognostic (1.55e-2)" "unprognostic (2.75e-1)" "unprognostic (2.54e-3)" "unprognostic (3.34e-2)" "unprognostic (2.44e-1)" "unprognostic (3.49e-2)" "unprognostic (1.61e-1)" "unprognostic (6.13e-2)" "unprognostic (1.67e-1)" "unprognostic (5.63e-3)" "unprognostic (3.49e-1)" "unprognostic (2.50e-1)" "unprognostic (1.85e-3)" 25.8 18.9 15.4 25.0 15.8 18.0 23.6 14.8 18.6 24.9 14.7 34.5 56.5 22.4 21.5 25.1 25.1 22.6 39.9 16.2 16.9 22.1 32.0 27.6 23.4 15.8 15.0 30.2 27.2 25.8 13.0 37.1 15.2 22.6 30.8 9.5 26.2 24.4 64.5 31.7 56.2 19.9 16.0 24.7 25.4 58.5 17.4 17.5 15.2 46.4 16.2 29.6 21.6 14.7 47.5 25.8 15.4 45.7 39.7 32.2 122.0 23.0 46.5 59.3 62.5 72.6 61.2 27.2 48.7 49.5 76.0 45.0 18.6 53.6 21.3 56.4 12.5 46.6 25.0 79.8 107.2 38.9 32.2 54.4 55.4 61.8 50.2 37.9 41.2 38.6 53.8 45.3 31.0 103.7 60.8 44.5 25.5 67.7 15.1 77.2 35.7 36.5 33.0 74.0 19.1 26.0 27.1 86.5 34.5 26.9 25.8 43.3 23.5 55.4 46.1 31.4 33.7 49.6 31.8 21.3 80.0 37.7 24.1 8.7 17.2 7.3 16.1 19.7 18.8 13.2 13.2 18.3 20.8 16.2 14.0 18.7 1.6 21.2 17.0 7.2 16.6 14.8 15.4 15.8 14.8 18.6 16.2 16.9 15.8 15.0 15.2 16.0 17.4 14.7 43.1 12.8 18.2 8.8 35.6 38.6 74.1 55.1 52.9 19.3 41.2 36.7 33.6 55.8 27.2 25.8 33.3 90.4 26.7 70.4 49.0 62.9 364.4 16.5 36.5 41.8 48.0 19.8 3.1 66.3 96.9 43.4 29.0 19.6 24.1 39.1 30.4 47.9 51.0 10.1 5.2 110.3 38.7 31.5 26.8 462.0 52.5 26.2 32.0 4.7 53.0 29.8 45.3 3.0 3.3 52.3 75.6 41.0 38.3 113.1 202.6 79.6 16.3 37.6 26.3 31.9 120.0 20.1 20.1 43.4 44.8 66.4 34.1 36.9 70.9 74.6 DPPA4 FLJ10713 ENSG00000121570 "Developmental pluripotency associated 4" Q7L190 3 109326141-109337572 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 4.7;lymphoid tissue: 12.2;testis: 4.1" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 22.3;Erythroid cells: 16.4;Extravillous trophoblasts: 17.2;Spermatogonia: 11.7;Syncytiotrophoblasts: 6.2" "Cancer enriched" "Detected in single" 218 "testis cancer: 59.0" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 12 "plasmacytoid DC: 7.3" "Lineage enriched" "Detected in single" 12 "dendritic cells: 7.3" "Group enriched" "Detected in some" 4 "HAP1: 89.7;NTERA-2: 327.5;SuSa: 120.7" "Not detected" "Not detected" "Not detected" "Not detected" "CAB020678, HPA035249, HPA035250" Enhanced Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome,Cytosol" Yes NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 5: NTERA-2 - Transcription" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoli, Nucleoli rim" "Nucleoplasm, Mitotic chromosome, Cytosol" "CAB020678: , HPA035249: AB_2674535, HPA035250: AB_2674536" "unprognostic (2.07e-2)" "unprognostic (2.53e-2)" "unprognostic (3.80e-1)" "unprognostic (2.53e-1)" "unprognostic (8.57e-2)" "unprognostic (1.80e-2)" "unprognostic (1.67e-1)" "unprognostic (1.52e-1)" "unprognostic (9.83e-2)" "unprognostic (2.02e-2)" "unprognostic (6.60e-2)" "unprognostic (2.48e-2)" "unprognostic (3.03e-8)" "unprognostic (5.28e-2)" "unprognostic (5.04e-2)" "unprognostic (5.56e-2)" "unprognostic (3.85e-2)" 0.0 0.0 0.0 0.1 0.0 4.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.7 2.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 4.1 0.0 12.2 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 43.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 89.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 327.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 120.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.1 0.1 0.0 0.5 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.6 0.0 0.0 22.3 4.3 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 16.4 0.1 0.0 17.2 0.5 0.0 0.0 1.3 0.0 0.4 1.6 1.7 0.0 0.1 0.0 0.0 0.3 0.0 0.6 0.3 0.4 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.1 0.7 0.0 0.0 0.9 0.3 0.3 11.7 0.0 0.0 6.2 0.5 0.2 0.0 0.3 DPY19L2 "FLJ32949, SPATA34" ENSG00000177990 "Dpy-19 like 2" Q6NUT2 12 63558913-63668939 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Spermatogenesis" "Developmental protein, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 65.6" "Group enriched" "Detected in many" 4 "Early spermatids: 329.9;Excitatory neurons: 124.1;Inhibitory neurons: 137.2;Late spermatids: 363.0;Oligodendrocyte precursor cells: 124.1;Spermatocytes: 143.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-266/84: 9.3" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA071264, HPA078305" Enhanced Approved Nucleoplasm,Mitochondria Yes No "Cluster 16: MAIT-cells - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 34: Spermatids - Unknown function" Mitochondria Nucleoplasm "HPA071264: AB_2686375, HPA078305: " "unprognostic (1.97e-1)" "unprognostic (4.08e-1)" "unprognostic (4.46e-3)" "unprognostic (2.50e-2)" "unprognostic (1.64e-1)" "unprognostic (1.17e-4)" "unprognostic (2.28e-2)" "unprognostic (2.14e-3)" "unprognostic (1.53e-1)" "unprognostic (3.64e-1)" "unprognostic (3.99e-3)" "unprognostic (1.97e-1)" "unprognostic (6.31e-3)" "unprognostic (4.22e-3)" "unprognostic (5.88e-2)" "unprognostic (8.90e-3)" "unprognostic (1.79e-1)" 6.7 5.3 4.0 0.5 3.9 3.0 4.7 7.0 6.9 11.4 6.6 5.2 0.6 7.8 4.1 1.4 6.4 2.8 19.2 3.0 4.3 12.7 0.2 1.3 0.9 2.4 3.0 11.0 2.7 9.0 10.5 1.2 1.5 9.3 1.3 14.4 1.6 4.7 0.5 1.6 1.7 3.5 0.8 1.7 2.9 65.6 3.3 0.7 13.1 0.6 0.6 6.3 5.1 4.2 1.0 2.6 2.2 5.4 0.6 0.0 0.2 1.8 1.8 2.4 3.1 0.4 0.8 2.8 1.8 0.7 2.9 0.4 2.7 0.3 3.6 1.5 1.7 4.6 1.4 1.7 0.5 3.4 1.4 1.5 0.1 1.1 0.0 6.1 0.8 2.2 1.9 2.9 3.9 1.7 0.2 1.4 2.1 0.4 2.4 0.0 1.8 0.0 4.6 0.5 7.0 0.7 0.6 0.2 1.0 0.9 1.9 0.9 0.5 3.2 4.2 0.5 4.6 7.5 9.3 0.0 3.4 1.6 3.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.1 4.0 3.9 7.0 6.9 3.0 4.3 2.4 3.0 1.5 0.8 3.3 4.2 6.7 3.2 0.0 23.2 0.2 0.5 2.9 0.1 2.2 49.6 1.9 1.8 32.3 1.5 3.8 12.9 14.6 2.0 0.3 0.1 5.9 0.4 329.9 5.6 7.1 1.7 0.0 7.2 124.1 0.0 1.3 2.2 0.5 2.1 2.5 1.2 1.4 0.1 0.3 3.3 137.2 0.1 6.1 0.0 0.4 363.0 7.2 0.4 7.2 11.2 0.1 9.2 0.0 124.1 5.0 0.2 0.0 8.6 0.5 2.9 0.0 6.4 11.6 6.7 26.3 3.8 19.9 143.3 4.9 0.2 0.4 1.4 0.8 3.6 0.1 1.1 DPYSL5 "CRAM, CRMP-5, CRMP5, CV2, Ulip6" ENSG00000157851 "Dihydropyrimidinase like 5" Q9BPU6 2 26847747-26950351 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 111.5" "Group enriched" "Detected in some" 4 "Cone photoreceptor cells: 85.5;Late spermatids: 134.3;Oligodendrocytes: 331.2" "Group enriched" "Detected in some" 15 "glioma: 17.7;testis cancer: 8.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "AF22: 141.0;HAP1: 118.7;SCLC-21H: 167.3;SH-SY5Y: 99.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034544, HPA072387" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 70: Brain - Nervous system development" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm Cytosol "HPA034544: AB_10671228, HPA072387: AB_2686516" "unprognostic (1.07e-4)" "unprognostic (1.10e-1)" "unprognostic (1.08e-1)" "unprognostic (3.64e-6)" "unprognostic (3.94e-1)" "unprognostic (6.21e-2)" "unprognostic (6.12e-2)" "unprognostic (2.66e-1)" "unprognostic (1.54e-1)" "unprognostic (3.54e-2)" "unprognostic (1.35e-1)" "unprognostic (1.77e-2)" "unprognostic (5.67e-3)" "unprognostic (3.62e-2)" "unprognostic (1.08e-1)" "unprognostic (2.43e-1)" 0.0 1.9 22.6 0.3 49.4 0.0 0.0 59.4 41.7 0.1 3.8 0.6 0.3 0.0 0.0 0.1 0.0 0.0 0.0 17.6 42.1 0.1 0.0 0.0 0.0 79.6 50.2 0.1 0.0 0.0 7.8 0.0 65.5 0.1 0.2 15.8 0.0 0.0 0.1 0.0 0.3 0.3 54.8 0.0 0.1 7.8 60.2 0.0 0.0 0.0 0.0 0.0 0.1 111.5 0.0 3.0 141.0 0.1 0.6 0.0 3.3 0.0 0.0 0.0 0.0 13.2 0.0 0.0 1.0 0.0 3.9 0.0 118.7 0.0 0.0 0.0 26.2 0.0 0.1 0.4 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.3 0.0 31.5 0.1 0.0 0.0 0.0 0.1 0.0 0.0 167.3 99.0 3.8 0.2 0.0 3.3 0.0 0.0 0.0 0.0 4.1 0.1 3.8 0.0 5.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.6 49.4 59.4 41.7 17.6 42.1 79.6 50.2 65.5 54.8 60.2 111.5 0.1 0.0 0.0 13.4 0.1 0.0 0.3 0.0 0.0 12.1 0.1 0.0 6.0 0.0 0.0 0.0 85.5 0.1 0.0 0.0 0.0 0.0 45.6 0.1 0.1 0.4 0.0 0.0 18.3 0.0 0.0 0.3 0.0 0.2 2.5 0.2 0.0 0.2 0.1 8.4 40.5 0.0 0.0 0.0 0.7 134.3 1.5 0.2 1.8 2.8 0.1 17.2 0.0 18.1 331.2 0.0 0.0 1.2 0.1 0.2 0.0 0.1 0.0 12.1 0.0 0.7 0.3 2.9 4.6 0.0 0.3 0.0 0.2 0.7 0.0 0.1 DR1 "NC2-BETA, NC2B, NCB2" ENSG00000117505 "Down-regulator of transcription 1" Q01658 1 93345907-93369493 "Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050785, HPA055308" Enhanced Supported Nucleoplasm NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "HPA050785: AB_2681237, HPA055308: AB_2682779" "unprognostic (1.46e-1)" "unprognostic (9.62e-2)" "prognostic favorable (4.79e-4)" "unprognostic (1.03e-2)" "unprognostic (2.08e-2)" "unprognostic (1.59e-1)" "prognostic unfavorable (9.95e-7)" "unprognostic (8.70e-2)" "unprognostic (6.71e-2)" "unprognostic (1.44e-2)" "prognostic unfavorable (9.11e-4)" "unprognostic (4.30e-2)" "prognostic unfavorable (7.23e-4)" "unprognostic (2.07e-1)" "unprognostic (2.29e-1)" "unprognostic (4.97e-1)" "unprognostic (1.60e-1)" 21.8 18.9 9.8 28.8 9.6 59.1 16.8 12.5 9.3 17.7 23.7 18.2 27.2 21.0 11.1 30.0 14.2 23.1 27.0 8.7 10.8 21.8 20.4 19.6 43.3 9.9 9.8 15.9 18.8 16.9 12.1 32.0 9.5 17.1 16.3 14.1 19.5 14.0 50.4 29.4 22.4 19.2 10.3 27.0 30.2 55.7 10.5 47.7 18.7 42.9 30.8 27.3 22.6 10.5 97.1 29.8 46.8 60.6 42.3 47.9 57.5 76.5 46.6 50.9 54.0 34.9 34.1 101.9 86.4 56.7 69.3 50.1 56.7 53.0 74.6 86.4 53.0 85.8 58.7 38.4 67.3 102.1 60.6 33.7 62.4 71.2 102.2 53.1 45.9 60.0 90.0 95.7 61.0 29.8 97.6 32.1 78.1 33.4 72.1 83.5 103.2 104.0 36.3 58.0 45.3 57.6 65.1 59.7 80.6 42.2 42.2 79.4 72.1 91.5 73.0 90.7 116.0 54.9 65.6 105.5 26.3 80.3 38.2 95.2 46.2 82.1 35.3 52.7 39.2 36.9 38.8 40.4 55.9 31.5 38.6 37.8 62.8 35.5 47.4 45.4 57.1 41.3 9.8 9.6 12.5 9.3 8.7 10.8 9.9 9.8 9.5 10.3 10.5 10.5 36.2 28.9 22.1 10.1 43.5 171.3 38.0 38.7 47.3 32.0 29.1 24.1 33.9 22.8 27.9 36.8 25.0 74.5 84.6 42.8 45.0 31.4 183.1 18.4 33.7 37.5 20.8 59.3 8.4 27.7 73.6 34.3 38.2 24.2 48.9 19.7 29.3 27.6 53.0 50.5 8.7 42.6 10.2 50.8 82.8 106.2 28.3 55.2 44.4 15.0 68.0 16.0 69.0 7.5 10.8 52.9 25.9 26.4 31.9 51.6 29.8 40.7 17.6 25.3 32.9 27.7 42.0 163.2 41.2 69.4 160.5 109.9 59.8 26.2 26.9 79.2 DRD3 ENSG00000151577 "Dopamine receptor D3" P35462 3 114127580-114199407 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets, Schizophrenia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 8 "brain: 5.6" "Group enriched" "Detected in some" 12 "Early spermatids: 6.2;Late spermatids: 19.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "basal ganglia: 5.6;cerebral cortex: 2.8;hypothalamus: 4.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in some" 5 "basal ganglia: 7.4" "Region enriched" "Detected in many" 10 "basal ganglia: 17.9" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 65: Brain - Ion transport" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (2.32e-1)" 0.0 0.0 0.3 0.0 5.6 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.3 5.6 0.0 2.8 0.1 4.1 0.0 0.2 0.5 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 19.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DRICH1 C22orf43 ENSG00000189269 "Aspartate rich 1" Q6PGQ1 22 23608452-23632321 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 17.0;testis: 46.4" "Group enriched" "Detected in some" 44 "Early spermatids: 405.5;Late spermatids: 589.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "CACO-2: 11.1" HPA020446 Approved Nucleoplasm,Nucleoli No No "Cluster 68: Epididymis - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Nucleoli" "HPA020446: AB_1853151" "unprognostic (7.48e-3)" "unprognostic (3.91e-2)" "unprognostic (2.02e-2)" "unprognostic (6.22e-4)" "unprognostic (6.46e-2)" "unprognostic (8.35e-4)" "unprognostic (2.74e-1)" "unprognostic (2.24e-1)" "unprognostic (1.06e-2)" "unprognostic (2.65e-2)" "unprognostic (5.73e-4)" "unprognostic (3.05e-1)" "unprognostic (1.92e-1)" "unprognostic (8.65e-2)" "unprognostic (8.68e-3)" "unprognostic (7.70e-4)" "unprognostic (1.08e-3)" 0.8 1.4 1.3 1.1 1.5 3.7 2.2 3.0 1.9 1.0 2.4 1.3 1.1 3.3 17.0 0.6 1.7 1.8 0.4 0.9 1.1 2.6 0.7 1.3 2.3 1.1 1.2 3.0 2.4 9.2 1.4 0.8 1.1 1.4 1.3 3.9 1.5 2.0 0.2 3.3 1.1 1.5 0.7 2.0 0.8 46.4 1.1 1.4 1.7 0.0 0.8 0.6 0.7 1.0 0.5 0.6 1.5 0.4 1.8 0.4 1.3 0.0 0.0 0.0 0.0 11.1 0.4 0.7 0.1 0.4 0.3 1.1 2.1 0.1 0.3 0.1 1.0 0.4 1.1 0.5 0.6 0.2 1.6 0.8 0.9 0.3 0.0 0.6 0.3 0.3 0.9 0.2 0.1 0.5 0.2 0.5 0.1 0.5 0.6 1.2 0.0 0.0 0.3 1.2 0.6 0.5 0.0 0.9 0.7 0.3 0.2 0.0 0.3 0.0 1.8 1.7 0.2 0.6 1.1 0.1 1.8 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.5 3.0 1.9 0.9 1.1 1.1 1.2 1.1 0.7 1.1 1.0 0.1 0.0 0.0 4.9 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 1.8 0.0 0.1 0.3 0.1 0.0 0.1 405.5 0.4 0.0 0.3 1.8 0.0 9.1 0.0 0.1 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.1 0.0 11.3 0.4 0.0 0.0 0.0 589.5 4.1 0.2 0.0 3.7 0.0 0.0 0.0 1.5 1.4 0.1 1.2 1.5 0.0 0.1 0.4 0.3 0.0 0.0 0.0 0.0 0.0 4.4 2.2 0.0 0.0 0.1 0.1 0.1 0.2 0.0 DSCC1 "DCC1, hDCC1, MGC5528" ENSG00000136982 "DNA replication and sister chromatid cohesion 1" Q9BVC3 8 119833976-119855894 "Predicted intracellular proteins" "Cell cycle, DNA replication" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 9.9" "Cell type enhanced" "Detected in many" "Erythroid cells: 24.6;Extravillous trophoblasts: 17.6;Spermatogonia: 18.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA023780, HPA024401" Uncertain Approved Nucleoplasm NA Yes "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA023780: AB_2671311, HPA024401: AB_2671557" "unprognostic (7.36e-3)" "unprognostic (8.24e-2)" "unprognostic (1.56e-1)" "unprognostic (4.71e-3)" "unprognostic (9.91e-2)" "unprognostic (1.14e-1)" "prognostic unfavorable (3.92e-6)" "prognostic unfavorable (3.93e-4)" "prognostic unfavorable (5.73e-4)" "unprognostic (3.24e-3)" "unprognostic (8.12e-3)" "unprognostic (2.72e-2)" "unprognostic (2.32e-9)" "unprognostic (2.75e-2)" "unprognostic (5.01e-1)" "unprognostic (4.40e-2)" "unprognostic (8.18e-2)" 1.8 1.8 1.3 3.7 1.6 6.1 2.4 2.1 2.0 2.6 1.1 2.7 2.4 2.4 1.3 2.4 1.5 1.0 1.5 1.4 1.4 0.9 1.1 1.4 7.1 1.5 1.5 1.5 2.8 0.5 0.5 2.3 1.6 1.9 3.5 0.3 3.7 1.2 2.1 2.6 2.3 2.7 1.5 1.3 1.7 2.6 1.4 9.9 1.0 3.4 5.7 1.5 2.1 1.8 34.3 16.6 32.1 29.4 4.6 8.3 13.8 23.1 4.7 16.3 16.9 15.2 20.4 61.7 19.7 6.9 10.1 24.8 36.7 14.4 17.5 42.2 33.3 78.7 16.2 17.9 1.5 31.2 26.4 3.8 2.2 20.1 9.7 3.8 4.7 40.5 27.2 26.9 19.9 33.8 82.4 19.2 47.2 90.4 41.2 29.1 30.4 29.9 12.7 21.3 28.7 17.6 12.4 96.7 15.8 25.0 18.1 17.0 3.2 17.7 48.0 17.2 33.9 36.5 58.2 65.4 9.0 49.2 26.2 0.0 0.0 0.0 0.9 0.0 0.7 0.3 0.2 0.4 0.0 0.1 0.1 0.3 0.0 0.8 0.0 0.2 0.3 0.2 1.3 1.6 2.1 2.0 1.4 1.4 1.5 1.5 1.6 1.5 1.4 1.8 4.7 0.0 0.5 2.6 1.2 3.4 2.2 2.1 4.6 0.7 2.2 3.2 0.8 1.5 0.2 0.0 0.0 7.9 1.6 1.0 0.0 1.6 0.1 0.8 2.8 3.0 0.0 24.6 6.4 2.4 17.6 4.3 1.5 1.3 4.5 3.7 4.6 0.9 4.7 0.0 5.2 1.2 2.0 1.0 1.2 0.2 1.2 0.9 3.6 1.0 0.0 1.5 1.0 7.5 5.3 0.5 0.3 2.6 5.2 1.7 0.2 1.5 1.7 0.3 0.0 2.3 3.3 1.1 18.8 6.0 3.3 1.4 3.0 2.0 3.8 1.5 DSG1 "CDHF4, DSG" ENSG00000134760 "Desmoglein 1" Q02413 18 31318160-31359246 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Hypotrichosis, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "skin 1: 564.4" "Group enriched" "Detected in some" 25 "Basal keratinocytes: 117.4;Suprabasal keratinocytes: 315.7" "Group enriched" "Detected in many" 10 "head and neck cancer: 57.0;melanoma: 16.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 23 "hTCEpi: 6.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA022128, HPA074188" Enhanced NA NA 130000000 "Cluster 61: Skin - Cornification" "Cluster 30: Epithelial cell lines - Translation" "Cluster 28: Keratinocytes - Keratinization" "HPA022128: AB_1847620, HPA074188: " "unprognostic (2.55e-2)" "unprognostic (8.87e-2)" "unprognostic (2.00e-1)" "unprognostic (4.13e-1)" "unprognostic (5.22e-1)" "unprognostic (1.81e-2)" "unprognostic (1.57e-2)" "unprognostic (2.00e-2)" "unprognostic (1.51e-1)" "unprognostic (1.04e-2)" "unprognostic (2.19e-1)" "unprognostic (6.15e-2)" "unprognostic (4.24e-3)" "unprognostic (2.87e-1)" "unprognostic (1.44e-1)" "prognostic unfavorable (2.99e-4)" 0.4 0.0 0.0 0.0 0.0 0.2 24.7 0.0 0.0 17.6 0.0 0.0 0.0 0.0 0.0 18.4 0.0 0.1 1.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 13.6 0.0 2.0 564.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.6 0.0 0.0 2.1 0.0 30.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 117.4 0.0 0.0 0.6 0.0 3.3 0.9 1.7 1.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.1 0.1 0.0 0.0 8.6 3.5 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 4.9 0.2 6.5 315.7 0.0 0.2 0.0 0.1 0.0 DTL "CDT2, DCAF2, L2DTL, RAMP" ENSG00000143476 "Denticleless E3 ubiquitin protein ligase homolog" Q9NZJ0 1 212035553-212107400 "Predicted intracellular proteins" "Biological rhythms, DNA damage, DNA replication, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 14.6;intestine: 4.7;lymphoid tissue: 14.2;placenta: 3.9;testis: 13.7" "Cell type enhanced" "Detected in many" "Early spermatids: 25.3;Erythroid cells: 36.2;Extravillous trophoblasts: 16.2;Spermatocytes: 53.2;Spermatogonia: 20.8" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "T-reg: 2.0" "Lineage enriched" "Detected in single" 8 "T-cells: 2.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA028016, HPA032023, HPA032031" Supported Supported Nucleoplasm,Nucleoli,Cytosol Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nucleoli, Cytosol" "HPA028016: AB_10611958, HPA032023: AB_2674114, HPA032031: AB_2674119" "unprognostic (7.61e-2)" "unprognostic (1.01e-3)" "unprognostic (2.14e-2)" "unprognostic (3.05e-2)" "unprognostic (2.19e-1)" "unprognostic (5.31e-2)" "prognostic unfavorable (4.41e-5)" "unprognostic (8.96e-3)" "unprognostic (2.45e-3)" "unprognostic (8.83e-3)" "unprognostic (2.52e-3)" "unprognostic (2.83e-2)" "prognostic unfavorable (1.71e-9)" "unprognostic (5.93e-2)" "unprognostic (2.01e-1)" "unprognostic (1.96e-2)" "unprognostic (2.82e-1)" 0.6 0.2 0.0 4.1 0.0 14.6 1.9 0.0 0.1 0.6 0.0 3.3 2.3 1.1 0.1 1.9 0.4 0.4 0.1 0.0 0.0 0.1 1.2 1.4 5.6 0.0 0.1 0.1 0.1 0.5 0.2 3.9 0.0 0.4 4.7 0.0 0.4 0.1 0.1 2.1 3.0 1.9 0.0 2.5 1.3 13.7 0.1 14.2 0.5 0.0 6.4 1.2 0.7 0.0 34.1 28.1 48.0 23.6 2.9 5.8 23.3 41.3 25.5 38.1 56.1 17.6 29.0 25.2 15.4 16.1 25.0 25.8 62.5 34.9 54.7 31.4 30.9 40.7 33.6 21.5 0.1 54.1 25.3 2.5 1.2 62.2 32.4 6.8 17.7 44.7 49.1 51.1 44.4 13.5 75.3 24.3 56.6 25.2 32.9 57.2 84.0 49.2 11.6 22.9 29.6 46.0 39.2 37.5 17.6 47.7 32.0 24.1 9.7 38.2 28.6 40.5 47.8 18.4 30.5 57.7 19.1 35.5 37.8 0.0 0.0 0.0 0.2 0.2 0.0 0.2 0.3 0.5 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 2.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.0 2.3 2.3 0.4 1.7 0.0 0.0 1.3 1.3 7.0 1.5 0.9 0.0 0.0 12.8 1.4 1.5 0.0 0.4 25.3 0.4 1.3 5.2 0.0 36.2 0.2 0.0 16.2 2.4 3.1 1.0 0.0 11.4 0.7 0.4 4.7 0.0 0.3 3.3 0.0 0.3 0.8 12.4 1.2 2.2 0.0 1.0 0.2 0.0 0.0 0.0 0.1 0.6 0.4 0.0 12.8 0.2 0.6 0.0 0.1 0.0 0.0 0.2 2.7 53.2 20.8 5.6 1.7 1.5 2.6 1.6 5.2 0.7 DTNA "D18S892E, DRP3, DTN, DTN-1, DTN-2, DTN-3" ENSG00000134769 "Dystrobrevin alpha" Q9Y4J8 18 34493290-34891844 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 461.9;choroid plexus: 120.6;heart muscle: 150.0;skeletal muscle: 166.9;tongue: 209.9" "Cell type enhanced" "Detected in many" "Astrocytes: 1756.1;Excitatory neurons: 506.0;Inhibitory neurons: 650.9;Oligodendrocyte precursor cells: 491.6;Oligodendrocytes: 367.4" "Cancer enriched" "Detected in many" 9 "glioma: 28.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "MCF7: 37.7;NTERA-2: 42.0;SCLC-21H: 51.9;U-87 MG: 52.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015196, HPA071177" Enhanced Approved "Nucleoplasm,Cell Junctions,Intermediate filaments" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 64: Astrocytes - Nervous system maintenance" "Cell Junctions, Intermediate filaments" Nucleoplasm "CAB015196: AB_2261797, HPA071177: " "unprognostic (1.57e-1)" "unprognostic (4.57e-2)" "unprognostic (3.13e-3)" "unprognostic (7.82e-6)" "unprognostic (5.03e-1)" "unprognostic (2.43e-3)" "unprognostic (2.73e-1)" "unprognostic (7.42e-2)" "unprognostic (1.23e-1)" "unprognostic (6.27e-2)" "unprognostic (1.35e-4)" "unprognostic (6.89e-2)" "prognostic favorable (2.64e-7)" "unprognostic (6.08e-3)" "unprognostic (3.93e-2)" "unprognostic (1.12e-1)" "unprognostic (7.27e-5)" 11.6 6.6 252.7 5.4 248.2 0.8 9.6 243.3 260.1 5.4 120.6 22.4 3.9 8.1 20.5 22.9 11.7 9.4 150.0 250.1 423.0 2.3 2.2 6.6 2.3 461.9 326.9 7.0 18.1 2.4 10.8 4.1 360.4 23.6 7.6 19.8 11.3 25.3 166.9 2.7 8.4 19.4 308.1 4.8 6.8 6.1 269.2 0.5 12.3 209.9 2.0 32.0 5.2 331.0 0.7 0.5 17.3 0.0 9.5 25.1 2.6 3.2 14.8 0.6 1.7 3.8 0.2 0.1 8.9 1.9 15.3 1.1 2.1 7.5 1.8 0.0 10.7 0.1 0.9 5.7 7.1 0.2 0.2 19.2 1.8 11.9 4.5 14.2 6.7 0.1 2.4 1.9 3.8 37.7 0.1 0.2 42.0 0.6 8.1 0.1 7.7 24.1 0.9 0.3 51.9 6.9 0.0 1.7 4.9 23.8 21.8 6.3 0.5 16.7 9.9 0.3 5.2 1.3 2.0 1.0 52.5 0.0 8.4 1.0 0.7 0.0 0.8 0.0 1.1 0.8 1.5 1.1 3.5 0.7 1.6 1.3 0.3 0.8 0.0 0.1 4.3 1.0 252.7 248.2 243.3 260.1 250.1 423.0 461.9 326.9 360.4 308.1 269.2 331.0 5.1 0.0 1.1 1756.1 0.1 1.5 0.1 0.8 0.0 18.3 22.2 12.3 134.3 27.1 1.4 0.0 6.2 0.1 0.4 0.0 5.9 12.6 3.1 7.0 2.6 6.4 0.0 0.0 506.0 25.1 0.1 5.7 0.0 0.4 0.0 2.3 0.0 0.2 9.0 1.7 650.9 0.1 4.1 4.0 21.5 3.7 5.9 8.0 5.4 105.9 0.9 34.0 0.0 491.6 367.4 8.0 0.0 0.4 0.0 1.8 0.1 2.0 7.1 3.8 13.1 22.7 17.3 0.9 4.8 0.2 1.0 0.0 0.2 0.3 0.2 0.2 DTNB ENSG00000138101 "Dystrobrevin beta" O60941 2 25377198-25673647 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 36.0" "Cell type enhanced" "Detected in many" "Excitatory neurons: 176.8;Inhibitory neurons: 214.1;Oligodendrocyte precursor cells: 137.7;Oligodendrocytes: 343.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" HPA061357 Uncertain Approved Mitochondria NA NA "Cluster 15: NK-cells - Transcription" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Mitochondria "HPA061357: AB_2684489" "unprognostic (1.14e-1)" "unprognostic (1.39e-2)" "unprognostic (3.17e-2)" "unprognostic (7.40e-2)" "unprognostic (1.17e-1)" "unprognostic (1.16e-2)" "prognostic unfavorable (2.54e-4)" "unprognostic (1.78e-2)" "unprognostic (3.67e-3)" "unprognostic (3.98e-2)" "unprognostic (9.45e-2)" "unprognostic (4.67e-2)" "prognostic favorable (3.47e-4)" "unprognostic (1.86e-1)" "unprognostic (1.40e-1)" "unprognostic (3.16e-2)" "unprognostic (6.49e-2)" 2.1 2.1 7.8 1.6 6.7 2.9 9.7 3.4 12.1 4.2 0.0 1.7 1.2 2.8 10.1 4.5 4.6 3.3 2.0 12.4 3.6 4.2 3.4 4.3 2.5 4.9 1.7 4.4 7.7 9.9 5.8 1.9 4.5 8.4 1.0 5.0 36.0 5.1 2.7 4.5 1.6 1.2 0.1 2.7 5.6 6.7 2.9 4.0 11.1 1.5 1.9 3.5 4.0 5.6 10.7 9.1 6.6 7.5 4.0 5.2 0.2 3.2 4.2 4.0 5.3 3.5 2.6 5.5 1.3 2.5 5.0 3.7 4.6 13.1 2.2 8.2 11.1 4.5 2.9 10.0 2.9 5.4 4.1 3.6 10.9 4.2 7.2 4.9 5.5 10.5 0.4 8.0 3.0 10.9 8.5 4.6 7.3 2.9 5.4 7.0 11.5 9.7 4.9 9.7 8.9 13.7 10.3 16.2 12.9 3.6 8.7 3.3 2.3 1.6 7.3 2.4 5.7 14.6 6.8 10.0 4.6 9.5 5.7 0.4 1.6 5.7 4.1 0.9 4.4 4.4 5.0 3.7 0.5 5.8 5.0 3.3 3.2 4.1 0.4 0.9 5.2 2.0 7.8 6.7 3.4 12.1 12.4 3.6 4.9 1.7 4.5 0.1 2.9 5.6 3.9 9.6 12.8 53.2 12.6 8.0 26.6 16.4 44.3 9.4 20.3 18.9 2.3 7.2 9.3 14.7 6.2 3.7 4.2 0.9 11.7 4.0 3.1 7.2 4.2 4.7 3.0 4.4 176.8 11.6 1.5 3.2 15.8 12.1 1.3 4.6 5.0 5.6 33.6 21.9 214.1 2.8 14.2 7.8 1.7 6.9 1.5 4.9 12.4 83.4 3.2 18.5 7.2 137.7 343.3 9.5 1.4 2.6 8.7 17.9 0.3 9.3 2.2 9.9 6.6 1.9 3.2 12.6 27.9 15.7 2.0 2.1 10.8 2.3 1.3 17.7 DUS4L "DUS4, PP35" ENSG00000105865 "Dihydrouridine synthase 4 like" O95620 7 107563484-107578523 "Predicted intracellular proteins" "tRNA processing" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044301 Approved Approved Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "HPA044301: AB_10967460" "unprognostic (7.95e-2)" "unprognostic (1.95e-1)" "unprognostic (1.33e-1)" "unprognostic (5.66e-2)" "unprognostic (1.82e-2)" "unprognostic (1.19e-1)" "unprognostic (1.28e-1)" "unprognostic (1.46e-1)" "unprognostic (1.03e-1)" "unprognostic (1.35e-2)" "unprognostic (1.98e-1)" "unprognostic (3.00e-2)" "unprognostic (2.56e-3)" "unprognostic (2.29e-2)" "unprognostic (9.21e-3)" "unprognostic (7.74e-3)" "unprognostic (6.72e-3)" 1.5 1.9 1.1 0.5 1.2 0.4 1.5 1.2 1.5 1.6 0.9 1.4 0.6 1.5 1.7 1.7 1.3 0.6 2.7 1.1 1.2 2.7 2.0 1.0 0.8 1.2 1.2 1.8 1.7 1.2 1.5 0.6 1.3 1.5 0.8 1.0 1.6 0.5 1.7 1.5 1.3 0.5 1.2 1.3 1.6 2.3 1.1 0.7 1.6 1.1 0.8 1.7 1.5 1.4 4.1 1.6 1.6 1.0 0.5 1.0 2.3 0.9 1.4 1.7 1.5 2.1 3.6 4.6 2.1 0.6 4.6 1.2 1.7 2.4 2.3 1.2 1.3 1.2 0.9 2.6 1.6 3.0 0.2 1.2 3.5 1.6 5.7 1.8 2.4 3.9 5.4 1.7 2.7 3.0 4.3 5.8 2.8 3.3 3.4 2.3 1.7 5.3 3.2 2.1 1.6 4.4 1.9 4.2 3.6 2.3 1.9 2.6 1.7 2.5 2.0 1.8 2.6 3.0 3.8 4.9 2.3 4.3 2.9 0.0 0.1 0.0 0.1 0.2 0.2 0.2 0.4 0.1 0.2 0.1 0.3 0.4 0.0 0.1 0.1 0.1 0.2 0.1 1.1 1.2 1.2 1.5 1.1 1.2 1.2 1.2 1.3 1.2 1.1 1.4 4.5 6.4 3.9 4.6 7.6 5.1 11.0 5.6 10.2 10.0 8.6 10.2 9.2 5.7 6.6 11.0 4.2 9.1 4.5 3.3 7.9 13.3 32.8 11.3 7.2 4.6 9.6 5.0 3.5 16.2 8.8 4.6 5.1 11.0 13.4 10.2 4.2 9.3 6.7 3.3 5.1 5.0 10.2 5.0 3.7 24.9 4.4 5.6 3.6 5.6 5.2 15.4 11.3 4.5 9.7 15.7 6.8 3.8 5.6 8.1 7.7 17.3 15.3 9.8 13.1 3.4 5.7 12.4 11.0 11.2 4.0 3.7 6.7 7.6 6.3 6.9 DUSP16 "KIAA1700, MKP-7, MKP7" ENSG00000111266 "Dual specificity phosphatase 16" Q9BY84 12 12473282-12562863 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 114.9;Oligodendrocytes: 196.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 3.9" "Lineage enriched" "Detected in single" 5 "T-cells: 3.9" "Cell line enhanced" "Detected in many" "NTERA-2: 37.7;RT4: 34.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020326 Approved Supported Nucleoplasm NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 18: Non-specific - Mitochondria" "Cluster 5: NTERA-2 - Transcription" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA020326: AB_1847890" "unprognostic (8.05e-2)" "unprognostic (9.47e-2)" "unprognostic (1.49e-3)" "unprognostic (4.14e-2)" "unprognostic (9.86e-2)" "prognostic favorable (1.01e-4)" "unprognostic (1.75e-2)" "unprognostic (3.52e-2)" "unprognostic (1.13e-2)" "unprognostic (2.11e-1)" "unprognostic (1.78e-1)" "unprognostic (2.82e-1)" "unprognostic (2.34e-3)" "unprognostic (6.35e-3)" "unprognostic (2.42e-1)" "unprognostic (1.46e-1)" "unprognostic (5.76e-2)" 9.3 47.8 4.9 7.8 8.3 3.6 15.0 7.7 5.3 12.2 6.3 11.3 13.6 11.3 6.2 12.7 10.5 8.0 7.2 4.8 6.0 7.6 33.3 12.0 6.4 7.3 8.1 10.7 18.8 8.0 12.9 5.5 6.2 19.7 10.9 7.5 14.6 3.4 11.3 11.1 13.1 4.9 5.4 6.8 13.2 7.1 6.7 15.2 8.8 4.7 9.0 10.7 17.0 11.8 4.5 6.5 7.6 4.2 2.8 3.3 13.6 2.6 5.8 6.4 9.1 18.1 8.6 0.4 1.4 2.9 11.3 2.9 14.1 2.4 8.6 14.4 7.0 0.7 6.8 19.2 5.4 1.3 3.0 2.8 6.7 5.1 16.3 6.8 5.0 7.3 4.0 11.8 0.4 8.6 1.7 0.9 37.7 11.1 1.9 2.0 2.6 8.6 3.6 34.3 12.3 11.5 10.6 13.6 6.7 28.2 5.5 2.2 4.5 2.9 8.3 1.8 2.9 8.3 10.6 1.5 3.8 2.9 4.0 0.0 0.0 0.0 0.5 0.0 2.3 0.0 1.6 0.7 0.1 0.0 0.5 0.3 0.8 0.0 0.0 0.0 3.9 0.3 4.9 8.3 7.7 5.3 4.8 6.0 7.3 8.1 6.2 5.4 6.7 11.8 9.6 28.9 55.5 30.3 3.3 2.8 14.9 1.5 3.4 4.8 23.8 13.1 11.5 20.0 9.7 3.7 2.1 10.5 5.6 35.7 0.0 14.3 1.3 15.1 10.2 9.2 49.6 0.0 19.5 24.6 4.1 9.9 11.7 19.9 23.5 114.9 7.5 34.2 5.3 6.7 24.8 10.0 2.0 9.4 1.9 2.3 5.9 5.7 5.4 38.4 2.9 36.8 0.0 56.3 196.3 20.9 25.3 6.8 4.3 34.3 25.4 5.2 10.4 4.8 0.0 11.1 10.3 3.0 5.8 6.2 1.8 30.1 27.9 9.9 18.7 24.5 DUSP21 ENSG00000189037 "Dual specificity phosphatase 21" Q9H596 X 44844021-44844888 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 41 "testis: 10.7" "Group enriched" "Detected in some" 99 "Early spermatids: 82.4;Late spermatids: 277.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (5.17e-2)" 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 10.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 82.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 277.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DUSP22 "JKAP, JSP1, MKPX, VHX" ENSG00000112679 "Dual specificity phosphatase 22" Q9NRW4 6 291630-351355 "Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPMI-8226: 270.6;U-266/70: 130.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031394 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 37: B-cells - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 25: RPMI-8226 - Immune response" "Cluster 51: Myeloid cells - Hemostasis" "Nucleoplasm, Vesicles" "HPA031394: AB_10604114" "unprognostic (7.34e-3)" "unprognostic (7.94e-3)" "unprognostic (1.37e-2)" "unprognostic (1.14e-1)" "unprognostic (3.46e-1)" "unprognostic (1.70e-2)" "unprognostic (9.08e-3)" "unprognostic (2.48e-1)" "unprognostic (9.06e-2)" "unprognostic (5.56e-3)" "unprognostic (3.10e-2)" "unprognostic (3.04e-1)" "unprognostic (1.77e-1)" "unprognostic (3.97e-2)" "unprognostic (3.07e-1)" "unprognostic (2.35e-1)" "unprognostic (1.09e-1)" 36.9 16.4 25.6 27.7 29.1 23.7 33.0 27.4 28.8 31.6 21.2 47.8 22.5 28.9 12.2 45.7 25.9 21.3 42.1 25.1 27.1 32.4 32.7 38.5 32.4 32.3 28.5 19.6 40.8 13.2 21.2 27.3 30.3 23.2 16.1 7.8 30.4 15.1 52.3 41.4 33.7 22.0 28.0 43.9 32.7 44.9 29.3 15.0 28.1 37.7 30.5 30.3 36.8 42.7 13.7 8.3 17.3 25.9 19.5 21.5 22.8 9.9 8.0 8.6 10.3 8.8 15.1 28.4 23.3 10.3 18.3 9.4 21.9 18.3 6.1 68.6 25.1 19.3 7.1 24.7 9.9 7.0 24.4 16.2 54.1 6.2 11.3 14.1 24.8 24.0 18.3 92.2 7.2 8.2 10.3 25.1 10.4 10.0 18.7 20.2 11.7 270.6 16.2 5.8 29.7 11.6 8.5 3.4 29.6 37.4 17.6 8.9 34.2 7.7 10.1 7.8 6.0 130.0 98.6 40.0 3.0 19.0 17.7 36.4 32.5 13.6 8.6 26.5 6.2 40.4 6.7 9.1 33.5 33.3 6.1 8.8 21.8 5.9 25.1 28.8 15.9 19.6 25.6 29.1 27.4 28.8 25.1 27.1 32.3 28.5 30.3 28.0 29.3 42.7 45.5 16.0 21.3 5.5 53.7 26.5 22.0 33.3 14.2 5.7 19.4 17.5 40.8 10.0 30.7 5.5 0.0 10.8 51.1 11.7 21.5 24.2 13.4 18.6 8.2 33.4 9.5 8.2 8.5 51.4 7.7 21.9 15.3 12.9 33.0 8.8 21.8 25.0 30.1 0.0 6.1 14.7 32.6 38.6 43.0 20.5 15.5 47.1 46.2 21.5 78.4 14.9 36.0 7.1 25.9 29.2 12.4 9.4 59.7 16.5 23.2 18.2 39.7 3.2 26.3 11.6 22.8 34.5 73.8 42.5 37.1 6.6 21.3 6.8 15.4 27.9 DUSP8 "C11orf81, FLJ42958, HB5, HVH-5" ENSG00000184545 "Dual specificity phosphatase 8" Q13202 11 1554051-1572271 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 25.5" "Cell type enhanced" "Detected in many" "Bipolar cells: 113.6;Distal enterocytes: 57.8;Glandular and luminal cells: 65.6;Horizontal cells: 90.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MCF7: 2.5;SCLC-21H: 1.4;SH-SY5Y: 1.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020071 Approved Approved Cytosol NA NA "Cluster 72: Non-specific - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 56: Bipolar cells - Visual perception" Cytosol "HPA020071: AB_1847903" "unprognostic (2.29e-1)" "unprognostic (4.15e-2)" "unprognostic (1.96e-1)" "unprognostic (4.00e-2)" "unprognostic (1.35e-1)" "unprognostic (7.58e-3)" "unprognostic (6.08e-2)" "unprognostic (1.11e-1)" "unprognostic (1.44e-3)" "unprognostic (1.81e-1)" "unprognostic (4.04e-3)" "unprognostic (1.82e-1)" "prognostic favorable (2.75e-6)" "unprognostic (1.51e-1)" "unprognostic (1.57e-1)" "unprognostic (8.65e-2)" "unprognostic (6.30e-2)" 6.6 2.1 3.5 0.2 3.0 1.0 6.0 0.3 8.1 5.1 0.0 11.3 0.0 8.4 0.6 1.4 8.7 0.5 17.0 5.0 0.1 5.4 3.6 9.5 0.3 1.9 0.4 2.4 15.7 0.2 25.5 0.1 0.1 5.1 0.3 1.6 6.1 0.2 13.3 4.3 6.8 1.2 0.3 3.1 8.3 3.1 0.7 0.2 3.7 0.0 0.1 3.6 4.2 2.0 0.6 0.3 0.4 0.0 0.0 0.0 1.1 0.1 0.4 0.1 0.6 0.6 0.0 0.0 0.2 0.1 0.0 0.9 0.0 0.1 0.3 1.1 0.6 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.7 0.0 2.5 0.0 0.1 0.1 0.0 0.7 0.0 0.0 0.3 0.0 0.0 1.4 1.7 0.1 0.2 0.3 0.0 0.1 0.0 0.0 0.1 0.8 0.3 0.8 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 3.0 0.3 8.1 5.0 0.1 1.9 0.4 0.1 0.3 0.7 2.0 14.9 3.2 1.1 0.0 6.3 9.8 8.1 2.7 2.8 113.6 32.1 24.3 6.0 14.3 3.2 12.9 47.9 0.3 11.1 57.8 1.9 7.7 0.3 31.5 24.7 6.5 42.3 0.0 11.1 11.3 0.5 4.3 8.6 65.6 0.0 0.4 1.4 0.6 0.5 90.9 11.3 32.6 6.1 0.0 3.4 0.2 0.6 4.7 5.4 2.8 1.0 22.3 1.0 3.0 5.2 11.0 22.4 0.4 4.7 17.4 19.1 1.6 2.8 35.5 6.6 8.0 15.1 0.8 0.6 2.2 4.8 5.9 10.5 0.7 25.0 14.2 DUSP9 "MKP-4, MKP4" ENSG00000130829 "Dual specificity phosphatase 9" Q99956 X 153642492-153651326 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 15 "kidney: 56.9;placenta: 72.6" "Group enriched" "Detected in some" 14 "Cytotrophoblasts: 1171.5;Distal tubular cells: 727.8;Syncytiotrophoblasts: 1735.1" "Cancer enhanced" "Detected in many" "liver cancer: 10.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 9 "Hep G2: 372.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA003336 Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 47: Cytotrophoblasts - Unknown function" "Endoplasmic reticulum" "HPA003336: AB_1078709" "unprognostic (4.64e-2)" "unprognostic (6.48e-2)" "unprognostic (4.87e-2)" "prognostic unfavorable (1.60e-4)" "unprognostic (1.52e-2)" "unprognostic (2.74e-3)" "unprognostic (9.36e-3)" "unprognostic (6.15e-2)" "unprognostic (2.81e-1)" "unprognostic (3.03e-1)" "unprognostic (1.29e-2)" "unprognostic (1.38e-2)" "unprognostic (2.68e-7)" "unprognostic (4.49e-2)" "unprognostic (2.08e-1)" "unprognostic (2.77e-2)" "unprognostic (5.52e-2)" 0.2 0.0 4.1 0.0 3.3 0.0 0.2 1.7 3.8 0.1 1.1 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 4.0 1.9 56.9 1.1 0.0 0.0 2.1 2.5 0.8 0.5 0.7 0.0 72.6 2.2 0.1 0.0 0.0 0.5 0.3 0.0 0.1 0.1 0.0 1.9 0.0 0.0 1.6 2.8 0.0 0.0 0.0 0.0 0.7 0.1 2.6 1.6 0.8 0.1 32.6 0.0 0.0 10.3 0.1 0.0 0.0 0.0 6.5 2.0 0.0 15.8 0.0 1.2 7.5 39.9 1.0 0.0 1.1 7.3 0.0 3.0 372.7 0.0 0.0 5.6 0.0 0.5 0.0 0.0 0.0 0.0 0.2 9.7 0.0 0.0 2.1 0.1 0.8 1.1 1.8 14.8 0.0 0.0 0.0 0.1 9.4 0.4 1.2 2.3 2.8 1.6 0.9 0.6 3.9 0.2 0.0 7.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 3.3 1.7 3.8 4.0 1.9 2.1 2.5 2.2 1.9 2.8 2.6 0.0 0.0 0.0 3.6 0.5 0.6 1.0 0.6 2.8 0.0 0.2 3.4 2.3 1.5 0.0 11.0 0.0 1171.5 0.0 0.0 727.8 0.1 0.0 0.1 0.1 3.1 0.0 0.0 0.7 0.0 84.0 6.1 0.0 0.0 0.0 3.8 0.0 0.9 84.2 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.4 0.0 0.8 0.0 3.2 0.4 0.0 0.0 0.0 0.4 0.8 8.9 0.2 0.0 1735.1 0.2 10.8 0.1 1.1 DYNC2I1 "CFAP163, DIC6, FAP163, FLJ10300, WDR60" ENSG00000126870 "Dynein 2 intermediate chain 1" Q8WVS4 7 158856558-158956747 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Adipocytes: 45.7;Cardiomyocytes: 83.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020607, HPA021316" Approved Supported Centrosome NA NA "Cluster 6: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 18: U-2197 - ECM organization" "Cluster 24: Non-specific - Transcription regulation" Centrosome "HPA020607: AB_1858817, HPA021316: AB_2215577" "unprognostic (1.22e-1)" "unprognostic (3.17e-2)" "unprognostic (2.05e-1)" "unprognostic (9.18e-3)" "unprognostic (3.07e-2)" "unprognostic (1.03e-1)" "unprognostic (5.88e-2)" "unprognostic (1.94e-1)" "unprognostic (3.58e-2)" "unprognostic (4.07e-2)" "unprognostic (4.13e-2)" "unprognostic (9.23e-2)" "unprognostic (3.11e-2)" "unprognostic (1.41e-1)" "unprognostic (1.89e-1)" "unprognostic (1.17e-3)" "unprognostic (1.98e-1)" 13.0 7.4 5.7 5.5 4.0 5.6 9.9 6.5 12.3 9.4 16.3 13.4 9.2 9.1 9.3 6.5 13.6 7.0 15.1 3.9 3.7 8.2 3.7 8.8 5.3 5.5 2.5 9.8 5.9 12.8 9.0 6.8 4.7 6.8 6.1 14.1 8.2 6.3 24.1 7.0 10.2 7.3 0.2 7.5 8.0 40.1 4.7 5.8 10.9 10.0 3.5 9.7 7.7 9.1 15.2 15.0 10.4 25.0 7.9 7.6 4.6 9.4 8.3 7.6 8.2 7.3 13.5 6.0 14.3 5.8 9.3 7.1 4.8 10.1 8.5 6.5 9.6 8.0 10.2 3.3 8.0 9.2 17.8 6.3 7.4 5.9 2.5 17.9 6.3 4.3 24.4 3.3 8.9 8.9 15.4 8.2 9.1 5.7 9.7 13.7 10.7 7.3 12.7 7.7 20.8 14.7 19.1 11.5 11.4 9.0 8.4 5.6 7.8 9.5 3.4 31.2 6.9 8.7 10.2 12.9 26.0 8.8 14.4 49.8 8.6 4.7 13.5 5.7 11.9 21.5 10.5 11.3 5.4 22.7 10.1 10.3 5.3 10.3 5.8 42.6 5.4 2.6 5.7 4.0 6.5 12.3 3.9 3.7 5.5 2.5 4.7 0.2 4.7 9.1 45.7 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 83.5 0.0 0.0 0.0 0.0 15.6 14.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.0 0.0 0.0 13.7 11.7 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.2 0.0 0.0 0.0 0.0 11.5 1.8 0.0 0.0 0.0 DYNC2LI1 "CGI-60, D2LIC, DKFZP564A033, LIC3" ENSG00000138036 "Dynein cytoplasmic 2 light intermediate chain 1" Q8TCX1 2 43774039-43810010 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Developmental protein, Motor protein" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 197.5;Respiratory ciliated cells: 133.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 14.8" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPTEC TERT1: 110.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062905 Approved Supported Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "HPA062905: AB_2684899" "unprognostic (3.46e-1)" "unprognostic (3.25e-1)" "unprognostic (1.75e-1)" "unprognostic (2.49e-2)" "unprognostic (2.89e-2)" "unprognostic (4.05e-2)" "unprognostic (1.84e-3)" "unprognostic (9.85e-2)" "unprognostic (2.87e-2)" "unprognostic (1.22e-1)" "unprognostic (1.85e-2)" "unprognostic (1.91e-1)" "prognostic favorable (2.73e-5)" "unprognostic (1.06e-1)" "unprognostic (1.48e-2)" "unprognostic (4.32e-2)" "unprognostic (4.60e-2)" 16.2 23.2 20.2 7.5 21.3 6.8 32.6 16.1 23.6 28.3 34.9 15.4 19.0 35.6 46.6 11.0 53.4 20.7 15.5 20.0 21.9 50.2 13.4 23.4 10.2 20.4 19.3 39.7 16.2 42.2 31.2 13.6 18.7 20.8 17.9 44.0 16.3 20.0 10.2 15.8 16.3 19.8 17.9 11.0 17.1 44.9 21.3 10.8 34.3 8.5 9.7 15.0 13.9 20.6 21.2 12.0 20.5 13.1 32.5 64.5 17.6 11.5 24.8 13.3 12.4 4.0 14.4 12.0 24.8 15.2 17.0 13.8 9.9 16.5 15.4 15.4 21.1 9.4 5.5 15.3 31.3 18.7 14.8 38.3 23.4 26.5 12.1 40.6 18.5 14.1 29.0 5.6 18.7 10.8 9.2 20.6 9.4 27.3 12.0 12.2 19.0 3.8 110.1 18.0 14.0 25.1 13.0 7.1 15.5 19.4 19.7 16.9 13.1 11.6 10.5 14.4 9.8 21.0 12.3 3.0 25.8 4.7 12.6 14.8 2.3 2.1 1.7 3.9 1.8 3.7 2.2 2.4 3.1 2.1 2.7 2.3 0.8 2.6 3.1 1.8 1.4 1.4 20.2 21.3 16.1 23.6 20.0 21.9 20.4 19.3 18.7 17.9 21.3 20.6 11.9 19.2 16.8 58.1 6.4 9.7 18.2 42.9 7.4 21.7 19.3 22.4 13.9 21.5 31.3 53.3 29.2 19.7 2.3 10.2 90.1 21.7 197.5 71.7 42.2 8.1 12.7 5.5 96.8 22.0 9.1 27.8 15.3 24.2 17.7 26.2 14.6 7.3 12.4 16.8 64.9 20.3 50.8 4.5 5.3 39.4 33.2 5.9 23.2 22.5 3.3 29.3 4.1 33.7 43.4 14.5 32.1 33.8 4.7 9.6 52.4 84.1 133.8 36.9 19.7 14.8 14.8 102.1 15.9 9.1 9.1 9.3 4.9 30.1 17.5 12.8 DYNLT2 "TCTE3, TCTEX1D3, TCTEX2, Tctex4" ENSG00000184786 "Dynein light chain Tctex-type 2" Q8IZS6 6 169740109-169751587 "Predicted intracellular proteins" Transport "Motor protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 30 "testis: 18.2" "Cell type enhanced" "Detected in some" "Adipocytes: 1.8;B-cells: 1.3;Cytotrophoblasts: 1.5;dendritic cells: 3.4;Endothelial cells: 1.1;Extravillous trophoblasts: 1.3;Plasma cells: 2.2;Smooth muscle cells: 1.7;Syncytiotrophoblasts: 1.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 24: Non-specific - Transcription regulation" "unprognostic (1.29e-1)" "unprognostic (1.70e-1)" "unprognostic (1.69e-1)" "unprognostic (2.22e-2)" "unprognostic (1.05e-2)" "unprognostic (6.15e-2)" "unprognostic (1.70e-2)" "unprognostic (2.63e-2)" "unprognostic (5.11e-2)" "unprognostic (1.87e-1)" "unprognostic (6.11e-5)" "unprognostic (1.58e-1)" "unprognostic (2.04e-10)" "unprognostic (1.16e-2)" "unprognostic (1.89e-1)" "unprognostic (1.35e-1)" "unprognostic (3.56e-5)" 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.6 0.2 0.2 0.2 0.0 0.2 0.2 1.8 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 1.5 3.4 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 1.3 0.8 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 1.6 0.4 0.0 0.0 0.0 DYRK1B MIRK ENSG00000105204 "Dual specificity tyrosine phosphorylation regulated kinase 1B" Q9Y463 19 39825350-39834201 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Diabetes mellitus, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 131.3;testis: 83.8" "Group enriched" "Detected in many" 12 "Early spermatids: 179.4;Late spermatids: 580.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SH-SY5Y: 14.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028522, HPA028786" Uncertain Supported "Nucleoplasm,Mitotic chromosome" Yes No "Cluster 15: NK-cells - Transcription" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "Mitotic chromosome" "HPA028522: AB_2672656, HPA028786: AB_10670831" "unprognostic (2.22e-2)" "unprognostic (9.86e-2)" "unprognostic (4.55e-2)" "unprognostic (3.45e-3)" "unprognostic (1.96e-1)" "unprognostic (1.13e-2)" "unprognostic (2.25e-1)" "unprognostic (2.39e-1)" "unprognostic (6.02e-2)" "unprognostic (3.67e-2)" "unprognostic (8.93e-2)" "unprognostic (4.22e-2)" "prognostic favorable (8.83e-4)" "unprognostic (9.73e-2)" "unprognostic (1.12e-1)" "unprognostic (2.53e-2)" "unprognostic (3.88e-2)" 9.5 19.6 4.8 2.7 4.8 4.7 10.9 4.1 6.2 12.5 4.8 12.4 5.3 11.9 7.8 11.7 13.8 3.3 20.0 4.7 3.6 16.2 7.5 8.8 4.6 3.5 3.4 11.6 10.3 6.5 31.5 2.7 3.6 13.0 2.1 4.1 14.3 3.3 131.3 14.8 10.2 2.6 1.2 14.0 12.1 83.8 3.6 5.2 16.5 49.9 2.5 11.4 10.5 3.0 0.4 9.3 8.8 6.2 4.9 4.6 0.7 2.9 1.8 2.6 2.3 0.9 3.6 1.4 11.0 3.4 0.1 3.2 1.3 2.0 2.3 5.4 7.8 0.6 5.9 0.9 4.1 0.3 1.9 6.2 1.2 0.8 2.9 8.6 0.6 3.5 1.5 2.0 0.4 4.7 2.1 0.8 2.2 2.7 2.1 1.0 0.2 0.6 5.7 2.2 12.7 14.5 4.5 4.4 0.2 4.6 4.4 0.5 4.5 1.1 2.0 1.0 0.9 3.2 1.1 1.0 7.4 0.9 0.4 0.7 1.6 1.8 3.0 1.7 3.6 2.4 2.0 3.1 1.9 1.6 1.0 1.7 2.5 3.3 1.6 4.5 2.2 1.7 4.8 4.8 4.1 6.2 4.7 3.6 3.5 3.4 3.6 1.2 3.6 3.0 6.0 0.0 0.6 6.2 10.9 3.4 3.8 8.4 10.2 15.2 9.0 6.1 6.1 7.2 3.4 16.5 20.9 2.1 21.7 10.3 9.8 13.1 179.4 15.4 6.7 7.3 20.4 19.8 4.6 4.3 1.7 5.1 7.7 10.1 1.3 11.9 12.1 3.9 5.9 10.1 6.3 9.8 10.2 8.2 3.0 580.2 7.2 4.7 5.4 7.5 5.7 8.3 10.3 5.0 3.2 9.7 9.7 5.3 5.0 4.8 11.5 17.4 10.7 13.0 0.0 11.1 4.8 30.1 13.4 6.1 2.8 1.4 10.8 20.2 7.4 3.6 DZIP1L "DZIP2, FLJ32844" ENSG00000158163 "DAZ interacting zinc finger protein 1 like" Q8IYY4 3 138061990-138115818 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 58.8;Respiratory ciliated cells: 74.0;Rod photoreceptor cells: 19.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030404 Approved Supported "Nucleoplasm,Microtubules,Cytokinetic bridge" Yes No "Cluster 45: Eosinophils - Innate immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 49: Ciliated cells - Cilium organization" Microtubules "Nucleoplasm, Cytokinetic bridge" "HPA030404: AB_10601548" "unprognostic (3.65e-2)" "unprognostic (8.37e-2)" "unprognostic (2.87e-2)" "unprognostic (3.71e-2)" "unprognostic (8.22e-2)" "unprognostic (6.50e-2)" "unprognostic (6.47e-4)" "unprognostic (1.54e-1)" "unprognostic (3.21e-2)" "unprognostic (3.13e-1)" "unprognostic (3.26e-1)" "unprognostic (1.69e-1)" "unprognostic (1.51e-2)" "unprognostic (2.35e-3)" "unprognostic (2.72e-1)" "unprognostic (9.98e-2)" "unprognostic (2.77e-2)" 4.9 1.4 1.7 2.2 2.2 8.8 4.7 5.9 2.1 8.6 15.3 5.0 2.2 8.1 1.9 2.5 12.8 5.7 3.3 2.2 2.3 5.6 1.0 5.7 0.9 5.7 7.4 7.0 6.3 2.7 2.1 2.0 4.2 4.1 1.5 4.6 2.1 3.3 1.0 7.8 2.1 4.6 4.3 2.6 7.2 4.1 2.6 0.4 3.6 0.9 0.7 6.1 5.3 2.2 5.4 3.1 6.1 5.1 3.8 5.1 1.4 8.6 5.1 5.0 6.3 2.0 0.4 0.0 4.3 8.0 7.0 1.7 4.5 2.0 2.4 1.2 4.4 2.4 7.5 0.3 3.1 1.8 4.0 5.4 2.0 5.5 2.6 5.1 2.8 1.4 1.8 0.0 6.9 0.3 0.0 0.8 7.4 0.0 1.1 0.0 7.1 0.0 2.3 8.5 2.1 4.8 8.9 0.0 4.3 3.4 2.3 3.7 2.2 12.3 5.6 6.0 4.5 0.0 0.0 0.1 4.9 2.6 4.8 0.0 0.3 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.7 2.2 5.9 2.1 2.2 2.3 5.7 7.4 4.2 4.3 2.6 2.2 1.4 3.2 2.0 4.2 0.0 3.6 0.6 1.9 7.4 8.6 0.2 2.5 2.9 7.2 7.7 1.8 8.4 0.1 0.0 0.0 5.9 3.8 17.4 58.8 8.5 2.6 0.0 1.3 4.0 1.2 0.1 6.5 7.1 1.1 0.0 7.4 0.0 0.0 1.4 3.3 2.9 0.0 2.0 3.2 2.6 1.8 6.2 3.5 0.0 3.7 0.6 2.7 0.0 2.5 0.2 5.9 0.0 4.1 0.0 0.4 0.0 0.8 74.0 19.4 0.0 7.2 9.8 0.6 2.3 1.7 4.3 0.0 0.5 1.7 0.0 0.1 E2F8 FLJ23311 ENSG00000129173 "E2F transcription factor 8" A0AVK6 11 19224063-19241620 "Predicted intracellular proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 14.2;lymphoid tissue: 11.8;skeletal muscle: 12.6" "Cell type enhanced" "Detected in some" "Erythroid cells: 34.1;Gastric mucus-secreting cells: 10.2;Plasma cells: 9.7;Squamous epithelial cells: 10.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA064882, HPA076614" Enhanced Supported Nucleoplasm,Nucleoli,Cytosol No No "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoli "Nucleoplasm, Cytosol" "HPA064882: AB_2685381, HPA076614: " "unprognostic (5.62e-2)" "unprognostic (5.24e-2)" "unprognostic (3.17e-2)" "unprognostic (6.99e-3)" "unprognostic (2.86e-2)" "unprognostic (1.66e-2)" "unprognostic (1.29e-5)" "unprognostic (1.94e-2)" "unprognostic (3.90e-3)" "unprognostic (2.41e-1)" "unprognostic (7.29e-4)" "unprognostic (1.16e-2)" "unprognostic (9.13e-8)" "unprognostic (1.02e-3)" "unprognostic (1.37e-1)" "unprognostic (3.81e-1)" "unprognostic (4.28e-3)" 0.3 0.1 0.0 2.8 0.0 14.2 0.5 0.1 0.1 1.0 0.0 4.0 3.8 0.4 0.0 4.9 0.9 0.4 2.1 0.0 0.0 0.1 0.3 0.3 7.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.2 0.4 5.1 0.0 0.9 0.2 12.6 3.0 3.0 0.6 0.0 1.3 5.6 1.7 0.0 11.8 0.1 0.4 7.3 1.8 1.3 0.1 23.3 7.2 7.1 9.8 0.4 1.1 31.7 13.0 3.7 15.3 16.4 25.4 7.8 23.5 5.5 4.3 9.0 20.2 17.2 1.6 13.5 15.9 14.9 8.0 4.1 7.1 0.0 12.7 19.2 0.3 0.1 3.1 1.0 0.9 21.0 17.2 17.6 22.1 6.3 11.6 25.8 16.6 6.9 26.3 10.1 26.9 12.8 16.0 6.6 16.8 6.0 7.0 5.5 11.3 1.3 4.0 7.7 13.7 4.2 7.3 9.0 18.3 11.8 7.7 16.2 30.6 9.0 24.4 18.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.3 1.1 0.1 1.3 0.0 0.0 0.3 0.1 3.8 0.0 0.5 0.0 0.0 0.9 0.8 2.5 0.0 0.0 0.4 3.3 0.8 0.8 1.2 34.1 0.1 0.0 1.7 1.0 10.2 3.3 0.0 3.1 0.0 0.0 2.4 0.0 0.0 3.9 0.0 0.0 0.0 0.6 0.0 0.8 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.3 1.2 0.0 9.7 0.1 0.4 0.2 5.6 0.0 0.0 1.5 0.9 4.0 3.1 10.0 0.3 0.3 2.2 0.5 6.3 0.9 EAF2 "BM040, TRAITS, U19" ENSG00000145088 "ELL associated factor 2" Q96CJ1 3 121835183-121886526 "Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 71.8;lymphoid tissue: 53.6" "Cell type enhanced" "Detected in many" "B-cells: 73.7;Plasma cells: 144.1;Proximal tubular cells: 128.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "memory B-cell: 104.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 73.5;HL-60: 114.9;THP-1: 59.9;U-698: 93.5;U-937: 64.0" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA008411 Enhanced NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 3: HMC-1 - Innate immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA008411: AB_1847950" "unprognostic (3.43e-1)" "prognostic favorable (2.25e-9)" "unprognostic (1.48e-1)" "prognostic favorable (2.66e-4)" "unprognostic (1.00e-1)" "unprognostic (3.18e-2)" "unprognostic (1.89e-3)" "unprognostic (7.04e-2)" "unprognostic (2.04e-1)" "unprognostic (2.18e-1)" "unprognostic (2.08e-1)" "unprognostic (1.14e-1)" "unprognostic (2.08e-2)" "unprognostic (2.55e-1)" "unprognostic (1.81e-1)" "unprognostic (9.04e-2)" "unprognostic (8.34e-2)" 4.3 2.6 2.3 19.5 2.0 71.8 10.0 2.1 3.1 5.5 1.5 10.3 8.9 2.0 4.9 2.7 1.4 5.0 1.7 2.7 2.4 30.2 3.5 4.3 53.6 2.1 2.4 1.0 4.2 3.1 3.3 2.9 2.2 21.0 11.6 1.7 7.6 8.4 0.8 1.0 7.7 3.5 1.4 16.9 8.2 4.6 3.0 7.7 1.7 1.3 43.4 7.8 1.4 2.0 3.5 3.0 2.0 2.5 0.7 2.1 6.0 1.3 0.8 2.4 4.4 5.8 2.0 73.5 1.5 0.3 7.7 5.7 5.0 3.0 6.0 35.8 2.9 42.4 3.0 11.1 1.0 114.9 44.7 1.0 6.9 2.8 2.6 0.0 2.3 10.0 5.0 14.2 1.1 1.0 16.3 15.1 2.9 13.8 2.5 17.1 6.4 11.2 2.4 4.3 2.5 0.6 2.1 2.0 5.7 5.5 1.8 59.9 0.7 1.5 2.4 1.4 3.4 25.4 12.2 93.5 2.8 64.0 4.7 11.9 18.8 42.8 1.4 41.2 2.8 104.4 2.2 1.5 22.5 97.4 2.9 1.6 3.5 1.8 54.7 30.5 2.7 13.1 2.3 2.0 2.1 3.1 2.7 2.4 2.1 2.4 2.2 1.4 3.0 2.0 4.5 3.2 4.2 48.0 73.7 2.4 6.9 25.0 6.2 1.3 5.9 6.6 4.3 0.0 16.5 1.8 4.2 15.5 15.3 2.9 17.6 4.4 36.4 4.3 2.0 2.5 1.2 10.3 17.3 17.6 2.2 4.9 7.7 7.7 10.1 2.5 3.9 1.6 16.5 0.0 28.6 5.7 16.2 32.4 15.7 4.6 5.0 29.8 16.0 8.4 29.5 9.4 6.2 12.1 7.7 4.2 4.7 3.0 144.1 11.1 2.4 128.0 9.1 5.3 0.0 4.5 4.6 37.6 18.1 2.3 2.4 7.7 11.1 2.2 3.5 5.9 EBF3 "COE3, DKFZp667B0210" ENSG00000108001 "EBF transcription factor 3" Q9H4W6 10 129835233-129973053 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 23.9;brain: 16.9" "Group enriched" "Detected in some" 5 "Adipocytes: 29.6;Endothelial cells: 13.1;Fibroblasts: 14.9;Skeletal myocytes: 33.5;Smooth muscle cells: 11.7" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 16.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 12.5;HAP1: 13.6;LHCN-M2: 25.4;NB-4: 35.7;RH-30: 13.2;SCLC-21H: 28.7;THP-1: 14.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA061169 Approved Nucleoplasm,Vesicles NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Vesicles "HPA061169: AB_2684441" "unprognostic (2.96e-1)" "unprognostic (3.78e-2)" "unprognostic (8.63e-3)" "unprognostic (2.60e-2)" "unprognostic (7.68e-2)" "unprognostic (4.50e-3)" "unprognostic (8.53e-6)" "unprognostic (2.93e-2)" "unprognostic (3.99e-2)" "unprognostic (1.04e-1)" "unprognostic (6.12e-2)" "unprognostic (2.63e-1)" "unprognostic (4.16e-3)" "unprognostic (1.37e-3)" "unprognostic (1.66e-1)" "unprognostic (9.49e-2)" "unprognostic (4.58e-2)" 23.9 0.6 0.3 1.0 0.1 0.1 13.7 1.4 0.2 4.1 0.4 2.7 0.2 2.3 0.8 1.4 4.8 2.4 9.4 0.1 2.7 0.5 0.5 0.2 6.9 6.5 8.5 1.0 1.3 2.1 0.9 2.5 3.8 2.4 0.5 1.9 3.0 1.1 7.9 3.3 1.0 1.5 16.9 0.2 1.6 1.6 3.2 1.3 7.3 7.7 1.0 3.3 5.5 1.1 0.0 0.0 0.6 0.1 12.5 10.3 0.1 0.8 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.5 0.0 0.0 13.6 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 2.4 0.0 0.0 0.0 0.7 0.0 0.0 25.4 0.0 0.0 35.7 0.0 0.0 0.0 0.3 13.2 0.0 0.0 0.1 28.7 0.4 0.0 0.0 0.0 0.1 0.0 14.3 0.0 0.0 1.3 8.7 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 1.4 0.2 0.1 2.7 6.5 8.5 3.8 16.9 3.2 1.1 29.6 0.0 0.0 0.3 0.0 1.9 0.0 0.0 0.0 1.8 0.3 0.6 3.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.3 0.1 13.1 0.0 0.0 0.9 0.0 0.0 14.9 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 1.5 0.4 0.3 0.4 0.0 1.9 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.7 0.0 33.5 11.7 0.0 3.4 0.1 0.9 0.0 0.2 0.1 0.0 0.1 EBNA1BP2 "EBP2, NOBP, P40" ENSG00000117395 "EBNA1 binding protein 2" Q99848 1 43164175-43270936 "Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026512, HPA028277" Approved Enhanced "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No 38000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Nucleoli rim" "Mitotic chromosome" "HPA026512: AB_1847954, HPA028277: AB_10603664" "unprognostic (9.30e-2)" "unprognostic (2.02e-1)" "unprognostic (1.05e-3)" "unprognostic (2.03e-2)" "unprognostic (8.59e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (4.22e-4)" "unprognostic (7.64e-3)" "unprognostic (2.89e-2)" "unprognostic (1.24e-3)" "unprognostic (7.11e-2)" "unprognostic (1.64e-3)" "unprognostic (4.10e-3)" "unprognostic (3.04e-3)" "unprognostic (1.69e-1)" "unprognostic (3.22e-2)" "unprognostic (1.33e-2)" 35.1 38.8 30.3 35.2 31.1 34.3 39.5 28.8 33.5 30.0 32.5 35.4 23.6 35.5 55.7 46.5 43.5 21.7 37.1 31.1 31.0 55.7 126.6 27.7 35.9 29.3 28.5 27.3 36.1 45.6 48.9 33.1 30.0 29.0 36.5 19.6 34.5 31.0 51.9 36.8 24.5 35.0 29.6 24.8 33.4 44.4 31.8 30.5 41.4 28.6 39.8 52.5 34.5 31.1 325.0 180.2 66.0 192.7 52.1 58.3 142.6 219.4 107.8 338.7 210.5 215.2 192.5 211.0 167.9 157.0 157.2 218.2 144.5 200.9 360.5 101.2 146.5 144.8 160.9 188.5 95.7 248.7 106.8 47.6 197.4 248.6 197.3 64.2 185.5 145.2 220.3 67.8 165.1 172.8 190.0 152.0 290.8 209.5 165.0 139.2 150.4 235.5 123.7 135.0 132.0 139.9 127.3 228.6 219.0 105.6 94.5 136.1 147.6 128.7 248.9 211.4 360.7 102.9 219.7 262.7 107.6 258.7 265.2 19.7 45.4 24.9 52.3 54.1 55.2 61.5 52.8 54.5 68.7 68.5 48.3 48.3 3.9 59.6 53.3 65.6 60.5 43.6 30.3 31.1 28.8 33.5 31.1 31.0 29.3 28.5 30.0 29.6 31.8 31.1 38.0 35.3 39.5 5.9 36.9 123.0 91.6 78.0 40.5 26.3 50.6 62.1 32.0 52.9 52.5 31.3 6.2 102.2 23.3 34.0 90.1 144.5 163.5 56.8 47.3 51.0 24.1 45.0 5.6 124.4 135.1 51.5 33.1 31.6 50.7 35.1 27.8 148.3 63.3 15.2 3.8 49.7 48.8 22.5 24.7 94.9 33.2 28.9 55.2 3.7 41.4 55.7 35.0 6.0 4.9 135.3 25.8 38.4 53.1 179.3 29.4 135.9 81.3 29.5 39.5 55.0 68.1 92.6 97.8 54.2 99.4 84.3 26.8 57.8 66.2 95.3 ECH1 HPXEL ENSG00000104823 "Enoyl-CoA hydratase 1" Q13011 19 38815422-38831841 "Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 749.9;skeletal muscle: 906.9" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 796.9;Proximal tubular cells: 880.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002907, HPA005835" Supported Supported Supported Mitochondria No No 720000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mitochondria" "Cluster 43: THP-1 - Innate immune response" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "HPA002907: AB_1847964, HPA005835: AB_1847965" "unprognostic (1.91e-1)" "unprognostic (3.03e-2)" "unprognostic (3.64e-2)" "unprognostic (6.43e-2)" "unprognostic (5.73e-3)" "unprognostic (6.90e-2)" "unprognostic (1.28e-1)" "unprognostic (1.79e-1)" "unprognostic (2.43e-1)" "unprognostic (5.86e-2)" "unprognostic (2.24e-1)" "unprognostic (3.37e-1)" "unprognostic (7.01e-2)" "prognostic unfavorable (2.23e-4)" "unprognostic (3.54e-1)" "unprognostic (3.52e-1)" "unprognostic (1.74e-2)" 216.0 343.0 51.2 47.6 53.7 62.3 194.2 54.1 60.3 124.9 58.6 232.9 93.5 115.3 32.3 168.4 114.0 66.8 749.9 49.3 52.5 271.6 556.1 122.1 67.8 51.8 51.8 107.2 141.4 56.0 77.1 67.1 53.4 99.5 99.9 12.8 138.6 43.3 906.9 149.0 167.4 59.7 50.6 192.3 180.5 100.7 55.0 51.0 117.9 455.1 65.7 142.4 132.4 53.3 64.0 273.8 42.0 68.8 161.0 82.0 61.8 31.7 53.2 26.6 27.1 178.8 124.8 98.6 117.2 72.8 24.1 30.1 70.9 72.9 21.1 345.3 37.7 120.7 76.5 146.1 161.3 131.9 116.9 109.0 186.6 35.1 61.2 52.3 63.4 127.3 58.4 160.8 59.6 120.0 91.8 82.2 27.8 278.8 65.9 101.8 126.2 199.0 168.7 142.6 51.4 67.2 161.0 77.1 86.5 27.3 106.4 288.4 53.7 45.5 39.3 46.5 29.6 121.0 153.2 96.4 71.4 164.9 90.7 316.1 312.9 268.0 253.6 248.2 237.2 368.4 243.5 249.1 308.6 361.3 216.5 242.4 41.6 342.7 212.8 221.5 391.8 541.8 51.2 53.7 54.1 60.3 49.3 52.5 51.8 51.8 53.4 50.6 55.0 53.3 125.4 86.6 104.7 13.1 111.1 82.2 220.0 320.8 80.8 22.4 124.0 143.8 302.7 205.9 203.2 145.3 16.7 796.9 103.4 257.7 510.6 195.4 64.5 95.7 56.9 96.4 189.2 99.9 7.1 90.1 370.6 104.1 112.7 77.0 120.9 177.6 90.7 549.4 277.6 37.0 8.6 298.9 193.3 99.0 85.2 56.7 130.8 97.5 145.9 8.4 205.1 53.0 113.3 7.1 16.0 97.0 257.5 143.0 122.1 100.1 383.0 880.0 182.6 21.4 78.9 88.4 119.7 73.3 51.3 121.6 90.8 580.9 118.6 624.2 350.0 218.1 ECHS1 SCEH ENSG00000127884 "Enoyl-CoA hydratase, short chain 1" P30084 10 133362485-133373354 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Lyase "Disease variant, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1128.7" "Cell type enhanced" "Detected in all" "Hepatocytes: 1476.3;Proximal tubular cells: 2336.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003783, HPA021995, HPA022476" Enhanced Enhanced Mitochondria NA NA 1200000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "CAB003783: , HPA021995: AB_1847974, HPA022476: AB_1847975" "unprognostic (3.68e-1)" "unprognostic (2.46e-3)" "unprognostic (9.57e-2)" "unprognostic (4.70e-2)" "unprognostic (1.59e-1)" "unprognostic (3.14e-1)" "unprognostic (2.51e-3)" "unprognostic (2.30e-1)" "unprognostic (1.82e-2)" "unprognostic (2.28e-2)" "unprognostic (1.60e-1)" "unprognostic (1.27e-1)" "prognostic favorable (8.57e-5)" "unprognostic (2.84e-2)" "unprognostic (1.19e-2)" "unprognostic (3.04e-2)" "unprognostic (2.50e-2)" 302.4 127.1 127.7 53.7 127.8 43.9 116.9 131.3 136.1 59.8 149.7 143.1 171.6 47.0 89.3 107.9 90.5 66.7 226.4 133.1 129.9 481.7 1128.7 48.5 52.4 129.4 129.9 71.3 96.8 98.7 74.3 73.6 128.8 102.0 104.6 39.8 163.4 123.2 294.3 68.2 153.6 59.4 130.3 48.4 84.5 52.6 134.6 40.0 88.5 271.6 59.0 87.4 57.8 136.0 185.1 229.2 120.4 303.4 173.0 111.4 110.5 132.2 175.9 183.2 154.1 509.5 174.0 139.2 111.9 151.4 94.4 167.7 160.2 136.1 132.0 107.4 281.2 138.5 128.1 367.2 145.0 180.4 93.5 124.5 115.9 121.2 153.6 160.8 165.1 98.3 127.8 117.4 181.6 443.9 90.7 352.0 84.4 289.8 272.1 152.8 146.4 74.6 227.8 236.0 78.1 123.4 137.0 224.1 178.9 69.4 174.8 171.5 132.1 81.3 115.9 169.9 177.4 87.0 58.8 159.8 192.4 98.8 68.7 96.1 184.7 86.8 105.5 212.2 137.6 178.7 117.8 115.8 242.6 148.9 119.3 115.8 19.8 166.0 168.1 104.9 123.0 233.0 127.7 127.8 131.3 136.1 133.1 129.9 129.4 129.9 128.8 130.3 134.6 136.0 99.2 44.8 82.7 16.3 60.5 68.2 86.9 271.8 62.6 57.0 98.5 119.6 255.2 210.1 161.5 174.7 6.2 470.2 34.0 298.6 565.4 162.8 29.9 148.9 92.7 71.4 131.7 72.2 11.6 101.1 163.5 92.5 87.7 226.4 91.2 120.0 88.5 1476.3 221.1 45.4 11.0 223.0 175.0 92.1 61.5 39.1 77.6 88.0 135.2 10.3 113.0 145.2 45.3 10.6 24.3 107.8 248.6 91.7 57.5 88.0 486.2 2336.5 93.2 55.2 85.5 57.0 98.8 52.9 66.1 125.2 76.3 299.1 62.5 220.0 317.2 127.8 ECSCR "ARIA, ECSM2" ENSG00000249751 "Endothelial cell surface expressed chemotaxis and apoptosis regulator" Q19T08 5 139448560-139462743 "Predicted membrane proteins" "Angiogenesis, Apoptosis, Chemotaxis, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 12 "Adipocytes: 235.8;Endothelial cells: 214.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 122 "EFO-21: 172.1;HUVEC TERT2: 443.7;TIME: 330.9" HPA063337 Supported "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Vesicles, Plasma membrane" Nucleoplasm "HPA063337: AB_2732701" "unprognostic (5.91e-2)" "unprognostic (2.37e-2)" "unprognostic (1.95e-2)" "unprognostic (2.83e-2)" "unprognostic (3.69e-2)" "unprognostic (2.15e-3)" "unprognostic (3.95e-2)" "unprognostic (1.12e-1)" "unprognostic (2.29e-2)" "unprognostic (1.78e-1)" "unprognostic (2.78e-2)" "unprognostic (1.91e-1)" "unprognostic (1.83e-3)" "unprognostic (2.41e-3)" "unprognostic (1.36e-1)" "unprognostic (9.90e-2)" "unprognostic (2.91e-1)" 62.7 12.7 5.5 11.2 5.5 0.2 59.8 5.7 8.5 26.8 5.3 19.4 4.6 29.4 7.4 15.9 33.5 12.1 54.6 5.2 5.9 29.9 6.0 60.1 11.6 6.0 5.9 10.4 6.7 4.7 7.1 33.5 6.3 19.6 8.0 0.8 16.1 7.3 15.1 16.6 20.7 24.4 6.1 23.5 15.2 3.3 6.7 3.5 40.9 17.2 7.2 35.5 26.1 5.9 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.3 0.3 0.0 0.0 172.1 0.3 0.1 0.0 0.0 0.0 0.6 1.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.1 443.7 0.1 0.0 0.0 1.4 0.0 0.0 0.9 2.5 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.4 330.9 0.4 0.4 0.0 1.7 0.0 0.0 0.2 0.0 1.5 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 5.5 5.7 8.5 5.2 5.9 6.0 5.9 6.3 6.1 6.7 5.9 235.8 0.0 3.9 0.0 1.0 14.9 0.4 0.0 0.0 0.0 1.9 2.5 0.0 0.0 0.6 0.0 0.0 0.2 1.0 0.0 0.0 0.6 0.0 0.4 0.5 214.9 0.0 0.0 0.1 1.2 0.1 3.1 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 18.3 0.0 0.0 1.7 10.6 5.6 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.5 0.0 0.0 0.7 0.4 0.0 0.0 1.9 0.0 0.0 0.0 13.9 0.3 1.3 0.9 0.0 1.6 ECT2 ARHGEF31 ENSG00000114346 "Epithelial cell transforming 2" Q9H8V3 3 172750682-172821474 "Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Neurogenesis, Protein transport, Transport" "Guanine-nucleotide releasing factor" Oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 64.6;Spermatocytes: 42.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA036363, HPA053261" Enhanced Nucleoplasm,Cytosol No Yes "Cluster 1: Neutrophils - Mixed function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "HPA036363: AB_2732472, HPA053261: AB_2682094" "unprognostic (3.83e-2)" "unprognostic (4.34e-1)" "unprognostic (1.27e-2)" "unprognostic (4.22e-3)" "unprognostic (4.49e-2)" "unprognostic (5.02e-3)" "prognostic unfavorable (6.82e-6)" "prognostic unfavorable (1.13e-4)" "unprognostic (1.82e-2)" "unprognostic (1.01e-1)" "prognostic unfavorable (2.24e-5)" "unprognostic (2.44e-2)" "prognostic unfavorable (1.19e-5)" "unprognostic (1.08e-2)" "unprognostic (1.46e-1)" "unprognostic (1.29e-1)" "unprognostic (1.33e-1)" 3.6 3.3 2.1 8.2 1.9 19.8 7.5 3.4 3.4 8.1 1.4 11.5 9.3 4.4 1.8 8.9 3.3 5.3 3.2 2.4 1.4 4.3 2.6 5.2 10.5 2.1 1.7 1.3 2.9 3.6 1.2 8.8 2.7 3.2 15.8 12.5 5.6 2.6 2.1 7.1 7.6 7.5 0.7 4.3 9.4 15.9 2.3 23.3 3.9 2.7 11.4 6.9 4.2 3.5 192.0 133.6 103.2 54.0 10.6 21.8 51.6 81.5 67.5 121.4 116.9 74.7 196.9 47.2 122.1 48.8 116.0 81.8 84.2 53.1 164.3 67.8 46.6 29.6 70.0 38.5 4.6 46.2 32.8 7.1 9.0 72.2 73.2 34.0 53.0 68.6 31.3 67.2 97.2 67.6 47.5 34.6 84.4 156.7 72.0 33.7 101.1 60.7 92.2 43.7 68.6 44.1 104.5 117.4 42.2 51.5 195.4 34.1 46.5 58.5 55.7 79.6 174.9 32.8 47.2 88.2 51.6 39.7 78.0 6.0 2.0 0.7 1.0 1.7 1.1 1.4 1.4 0.9 1.6 1.3 0.6 0.9 6.3 0.7 0.7 1.6 2.5 0.7 2.1 1.9 3.4 3.4 2.4 1.4 2.1 1.7 2.7 0.7 2.3 3.5 6.7 6.4 3.2 4.2 3.8 19.5 4.9 6.2 9.1 3.4 10.1 6.5 3.6 5.7 5.7 3.7 64.6 12.0 2.9 10.7 0.0 9.5 3.3 20.1 6.6 7.7 4.8 25.2 6.5 9.2 14.9 6.0 17.9 20.5 0.0 17.9 5.3 2.9 7.3 0.0 2.5 13.5 10.2 4.7 6.3 2.8 0.9 5.1 7.2 15.0 2.8 3.1 2.1 3.0 4.9 20.7 3.8 1.5 9.6 12.8 1.5 3.7 11.0 16.3 0.0 2.9 5.2 42.6 30.4 16.9 12.8 3.8 4.1 3.3 13.5 8.8 EDNRB "ETB, HSCR, HSCR2" ENSG00000136160 "Endothelin receptor type B" P24530 13 77895481-77975529 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Albinism, Deafness, Disease variant, FDA approved drug targets, Hirschsprung disease, Waardenburg syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 127.8" "Cell type enhanced" "Detected in many" "Adipocytes: 120.5;Astrocytes: 126.3;Hepatic stellate cells: 112.5;Melanocytes: 110.3;Muller glia cells: 116.2;Sertoli cells: 216.9;Skeletal myocytes: 81.3;Smooth muscle cells: 102.1" "Cancer enhanced" "Detected in all" "melanoma: 127.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 68.0;ASC diff: 50.5;SK-MEL-30: 66.0;U-266/70: 40.7;WM-115: 131.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017842, HPA027546" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" Cytosol "CAB017842: , HPA027546: AB_2672327" "unprognostic (7.75e-2)" "unprognostic (6.73e-2)" "unprognostic (1.41e-3)" "unprognostic (2.59e-2)" "unprognostic (8.37e-2)" "unprognostic (2.45e-3)" "unprognostic (4.17e-3)" "unprognostic (5.43e-2)" "unprognostic (1.02e-1)" "unprognostic (1.38e-2)" "unprognostic (3.40e-2)" "unprognostic (3.01e-2)" "prognostic favorable (7.20e-5)" "unprognostic (1.59e-2)" "unprognostic (3.86e-2)" "unprognostic (4.58e-2)" "unprognostic (6.77e-3)" 58.8 41.2 34.7 19.5 50.8 0.9 39.8 44.6 26.1 18.7 6.7 13.0 20.0 13.1 3.7 8.2 14.1 14.9 28.1 27.5 51.6 33.0 50.9 51.2 10.4 76.2 66.0 4.7 11.4 15.3 9.6 127.8 47.9 25.3 13.2 17.9 27.0 6.9 11.3 12.5 21.9 12.9 97.2 16.8 10.6 2.3 64.9 4.0 31.8 18.8 4.7 23.6 15.5 78.7 5.7 0.0 68.0 0.0 50.5 2.0 1.0 0.0 0.1 0.0 0.0 25.9 0.0 0.0 2.6 0.0 0.1 0.2 0.0 0.0 0.0 0.3 0.3 0.3 0.0 0.0 3.5 0.0 0.2 13.2 0.0 0.0 0.0 0.1 0.6 0.0 0.2 0.2 1.7 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.1 0.7 0.1 0.1 0.5 0.1 0.0 66.0 8.9 0.0 0.3 0.3 0.6 0.1 0.0 0.4 40.7 24.9 0.1 1.2 0.0 131.8 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 34.7 50.8 44.6 26.1 27.5 51.6 76.2 66.0 47.9 97.2 64.9 78.7 120.5 12.8 51.0 126.3 0.2 14.8 1.0 0.0 1.2 5.8 1.2 2.8 10.8 0.0 2.5 0.0 6.2 14.7 0.3 0.1 0.0 0.0 2.9 2.9 20.7 73.3 0.0 0.0 1.3 0.0 13.9 51.1 1.1 35.9 6.3 2.1 112.5 1.1 13.4 0.0 1.6 0.0 0.0 18.7 10.6 2.2 79.9 5.2 110.3 6.5 0.1 116.2 0.0 48.2 0.9 0.1 0.0 2.6 0.1 2.6 0.0 0.1 1.5 4.4 216.9 81.3 102.1 0.4 2.1 0.2 7.2 5.7 1.6 2.5 0.0 1.5 EEF1D "EF-1D, FLJ20897" ENSG00000104529 "Eukaryotic translation elongation factor 1 delta" P29692 8 143579697-143599541 "Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis, Transcription, Transcription regulation" "DNA-binding, Elongation factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045101, HPA051002" Supported Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA 1300000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 32: Non-specific - Translation" "Nucleoplasm, Nucleoli fibrillar center" "HPA045101: AB_10963077, HPA051002: AB_2681305" "unprognostic (9.34e-2)" "unprognostic (2.37e-2)" "unprognostic (9.92e-2)" "unprognostic (1.63e-3)" "unprognostic (5.25e-2)" "unprognostic (2.06e-1)" "prognostic unfavorable (3.82e-4)" "unprognostic (8.56e-2)" "unprognostic (3.74e-1)" "unprognostic (2.98e-1)" "unprognostic (1.80e-1)" "unprognostic (1.76e-1)" "prognostic unfavorable (2.58e-5)" "unprognostic (3.99e-2)" "unprognostic (2.06e-1)" "unprognostic (2.67e-2)" "unprognostic (2.14e-1)" 556.9 600.9 278.8 254.4 299.8 474.5 552.1 276.4 339.0 638.4 302.9 716.0 205.3 497.5 228.5 524.8 523.0 179.7 795.4 267.2 277.0 491.3 582.9 435.3 380.0 303.4 283.3 979.4 1349.3 160.2 328.0 147.2 292.4 609.2 148.3 67.1 577.0 201.9 916.1 615.8 505.9 179.9 281.5 609.6 634.3 288.1 281.7 338.7 504.0 433.0 307.3 538.2 554.0 322.1 454.8 644.8 284.2 246.0 251.0 307.0 314.2 344.2 438.4 536.7 424.0 886.7 420.0 345.5 352.2 386.6 160.4 441.8 295.3 556.0 231.7 274.8 487.6 340.6 1211.8 881.5 373.6 214.1 276.9 594.8 796.6 325.1 367.8 309.6 364.5 282.0 325.2 497.6 309.3 1456.4 838.7 539.7 300.3 580.3 852.3 367.2 204.4 681.0 466.3 757.9 280.0 301.6 300.1 726.3 762.5 174.1 544.3 535.7 285.2 309.9 914.8 465.5 757.5 335.2 142.9 380.2 348.4 431.6 275.3 268.2 535.1 259.6 880.1 503.5 1128.3 1400.1 1110.3 922.6 619.1 1461.9 1365.3 1110.3 408.6 864.7 458.9 874.2 1191.8 2020.0 278.8 299.8 276.4 339.0 267.2 277.0 303.4 283.3 292.4 281.5 281.7 322.1 652.3 163.5 415.9 47.7 1397.8 1846.0 1620.8 1277.4 1438.7 75.7 1568.2 2028.8 3.9 732.0 600.3 342.1 20.9 665.5 942.8 718.8 855.0 751.4 413.0 173.0 441.3 705.7 343.3 639.1 11.3 1793.7 822.0 699.2 520.9 263.8 446.1 931.0 871.7 792.9 799.6 79.1 13.0 971.5 526.9 1361.3 1492.3 1087.1 891.3 823.6 1085.1 17.8 1400.9 502.7 1071.1 15.6 30.2 938.4 799.5 633.1 1098.8 1566.2 998.9 1552.3 241.7 88.9 479.9 1005.6 844.4 34.0 142.2 969.5 1648.6 712.5 1297.8 573.3 870.0 1619.4 EEF2KMT "EFM3, FAM86A, MGC19636, SB153" ENSG00000118894 "Eukaryotic elongation factor 2 lysine methyltransferase" Q96G04 16 5084284-5097795 "Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 9 "Early spermatids: 189.0;Late spermatids: 393.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPMI-8226: 104.8" "Low region specificity" "Detected in all" HPA041610 Approved Uncertain Vesicles NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 71: Testis - DNA repair" "Cluster 25: RPMI-8226 - Immune response" "Cluster 34: Spermatids - Unknown function" Vesicles "HPA041610: AB_2677581" "unprognostic (4.50e-2)" "unprognostic (1.53e-1)" "unprognostic (8.89e-3)" "unprognostic (3.95e-2)" "unprognostic (2.01e-2)" "unprognostic (7.70e-2)" "prognostic unfavorable (8.85e-4)" "unprognostic (3.53e-1)" "unprognostic (1.37e-1)" "unprognostic (4.03e-2)" "unprognostic (9.73e-2)" "unprognostic (1.53e-1)" "unprognostic (5.24e-3)" "unprognostic (1.82e-1)" "unprognostic (2.07e-1)" "unprognostic (2.75e-2)" "prognostic unfavorable (2.35e-4)" 4.6 5.9 3.2 4.0 3.2 1.1 4.9 2.9 3.4 5.0 3.3 5.0 5.1 6.6 2.7 6.0 4.9 2.8 5.7 2.7 3.4 6.8 8.2 3.7 4.5 3.4 3.5 3.7 6.8 5.8 5.0 2.3 3.4 4.8 3.5 1.1 5.4 4.3 8.5 4.3 4.1 5.2 2.9 4.7 5.3 10.6 3.9 2.4 4.9 3.4 3.5 6.0 4.5 2.9 6.3 20.1 8.9 16.5 9.2 7.3 11.3 11.8 6.7 11.6 7.3 15.1 18.2 17.9 7.6 12.2 15.1 13.5 14.5 14.6 8.5 18.7 15.3 7.7 8.6 25.5 11.5 16.4 9.5 8.4 10.9 13.5 23.6 5.4 11.6 21.3 13.8 16.1 9.6 42.0 7.7 9.8 16.3 33.7 13.6 17.9 9.9 104.8 12.6 8.1 11.0 9.2 14.4 20.0 8.6 6.9 14.0 5.7 7.1 18.7 12.6 59.8 12.3 10.3 13.8 11.8 5.4 12.9 18.3 10.1 7.2 0.7 10.7 13.7 15.8 12.8 10.4 11.6 9.7 9.5 7.9 11.9 0.9 10.5 17.2 2.8 17.8 8.3 3.2 3.2 2.9 3.4 2.7 3.4 3.4 3.5 3.4 2.9 3.9 2.9 7.2 3.2 3.7 0.3 8.6 0.0 9.1 0.0 8.0 2.6 9.7 11.4 1.1 7.2 2.5 5.5 0.0 6.0 3.6 1.8 31.3 18.5 189.0 6.8 14.7 7.3 3.6 3.8 0.7 18.3 12.5 6.0 6.1 4.2 1.3 9.9 6.4 9.9 14.6 6.7 0.9 4.6 0.0 4.1 0.0 393.3 7.8 5.8 0.0 1.9 5.7 7.3 6.2 0.5 1.5 17.0 2.9 3.8 10.2 23.4 3.4 19.6 7.3 2.8 0.0 5.3 6.4 5.8 16.8 12.8 0.0 4.1 5.9 16.2 5.3 8.5 EFCAB2 "CFAP200, DRC8, MGC12458" ENSG00000203666 "EF-hand calcium binding domain 2" Q5VUJ9 1 244969705-245127164 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 112.3;Endometrial ciliated cells: 103.1;Late spermatids: 132.5;Respiratory ciliated cells: 177.2;Spermatocytes: 115.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 8.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HMC-1: 77.1;THP-1: 70.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031206, HPA031207" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 3: HMC-1 - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane, Cytosol" "HPA031206: AB_10599710, HPA031207: AB_10599946" "unprognostic (1.36e-2)" "unprognostic (9.04e-2)" "unprognostic (1.09e-1)" "unprognostic (2.84e-2)" "unprognostic (3.13e-2)" "unprognostic (1.21e-1)" "unprognostic (4.47e-2)" "unprognostic (9.86e-2)" "unprognostic (2.85e-2)" "unprognostic (3.02e-1)" "unprognostic (4.34e-3)" "unprognostic (8.41e-2)" "unprognostic (1.48e-2)" "unprognostic (2.25e-2)" "unprognostic (1.64e-1)" "prognostic unfavorable (6.51e-4)" "unprognostic (4.88e-2)" 13.0 10.6 11.5 6.7 13.8 14.4 16.0 14.4 21.9 8.7 26.7 6.8 3.3 21.2 17.5 10.5 36.1 14.7 15.0 11.4 14.4 11.1 5.6 12.6 9.6 18.1 16.9 11.3 9.0 15.4 8.5 16.8 13.9 8.9 12.4 17.7 8.8 13.1 19.7 6.9 7.4 11.4 14.9 7.5 12.4 28.0 12.9 7.4 26.8 7.5 10.7 8.2 4.9 16.3 7.3 9.1 20.3 5.2 7.2 16.7 24.7 9.2 9.7 11.5 10.6 23.5 19.5 25.3 19.2 11.6 12.2 5.7 8.2 5.3 7.1 2.7 5.0 12.4 41.3 10.7 15.2 12.8 77.1 14.6 11.0 15.5 14.4 13.7 18.0 0.7 48.0 20.1 10.0 7.6 2.6 34.6 26.0 10.4 6.9 48.4 3.1 6.8 29.0 12.3 15.9 21.4 16.0 6.1 13.6 22.7 5.9 70.5 2.8 14.1 5.3 7.9 33.7 6.9 12.4 17.2 11.2 35.9 11.7 0.9 1.3 2.3 0.4 1.4 0.5 3.1 0.5 0.3 4.3 3.3 0.4 0.4 3.8 2.3 1.1 8.7 0.6 1.0 11.5 13.8 14.4 21.9 11.4 14.4 18.1 16.9 13.9 14.9 12.9 16.3 13.3 3.2 14.5 76.0 11.5 5.1 11.8 17.2 10.2 12.6 11.6 11.0 58.6 8.6 23.0 23.9 14.6 16.3 9.3 5.4 50.9 8.2 112.3 103.1 18.5 11.7 18.8 17.2 54.6 10.8 46.3 15.5 11.2 11.1 0.0 13.6 12.5 7.3 11.2 5.0 90.3 6.5 22.4 21.3 6.5 132.5 9.0 13.2 7.2 42.2 6.6 19.2 1.0 74.9 75.9 5.6 6.6 6.4 12.0 7.1 2.7 35.6 177.2 19.1 6.6 15.5 15.8 115.9 30.6 5.4 3.0 34.2 7.5 8.3 6.9 10.6 EFCAB5 FLJ46247 ENSG00000176927 "EF-hand calcium binding domain 5" A4FU69 17 29929200-30108452 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "testis: 8.5" "Group enriched" "Detected in some" 4 "Early spermatids: 136.5;Late spermatids: 101.0;Spermatocytes: 65.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "basophil: 2.4;eosinophil: 3.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "MOLT-4: 2.1;RPTEC TERT1: 2.9;SK-MEL-30: 2.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (5.75e-2)" "unprognostic (2.54e-1)" "unprognostic (4.38e-2)" "unprognostic (2.22e-1)" "unprognostic (2.30e-1)" "unprognostic (3.74e-1)" "unprognostic (8.52e-2)" "unprognostic (2.40e-1)" "unprognostic (5.08e-4)" "unprognostic (3.13e-1)" "unprognostic (3.22e-2)" "unprognostic (6.77e-3)" "unprognostic (9.86e-4)" "unprognostic (7.93e-2)" "unprognostic (2.11e-1)" "unprognostic (6.74e-2)" "unprognostic (3.11e-5)" 0.0 0.1 0.4 0.2 0.1 1.2 0.0 1.1 0.4 0.0 0.2 0.8 0.1 0.0 0.1 0.0 0.1 0.1 0.3 0.1 0.9 0.3 0.0 0.1 0.4 0.2 0.4 0.0 0.0 0.1 0.0 0.1 0.2 0.0 1.1 0.1 0.0 0.0 0.1 0.3 0.4 0.2 0.0 0.1 0.3 8.5 0.3 0.1 0.2 0.0 0.4 0.0 0.0 0.9 0.3 0.4 0.3 0.0 0.4 0.6 0.0 0.6 0.1 0.0 0.4 0.0 0.9 0.5 0.3 0.9 0.3 0.4 0.1 0.6 0.5 0.2 1.7 0.0 1.1 0.4 0.2 0.5 0.3 0.0 0.0 0.1 0.0 0.7 0.2 0.7 0.0 0.1 0.0 0.0 2.1 1.0 0.1 0.4 0.0 0.7 0.8 0.8 2.9 1.2 1.3 0.2 0.8 0.5 2.3 0.3 0.0 0.2 0.6 0.1 0.3 0.4 0.0 0.0 0.0 0.8 0.2 0.2 1.1 2.4 0.0 3.2 0.1 0.1 0.0 0.5 0.1 0.2 0.0 0.9 0.2 0.0 0.1 0.1 0.0 0.0 0.5 0.0 0.4 0.1 1.1 0.4 0.1 0.9 0.2 0.4 0.2 0.0 0.3 0.9 0.3 0.0 2.0 0.7 1.5 0.3 0.2 0.1 0.0 0.8 0.7 0.6 0.7 1.5 0.1 3.7 0.0 0.3 1.7 1.4 1.9 0.0 136.5 1.7 0.2 0.4 0.0 0.4 23.3 0.2 0.2 0.3 0.5 1.1 5.1 0.2 1.4 0.4 0.2 0.0 15.0 0.8 0.0 0.0 0.2 101.0 1.8 0.6 7.2 2.8 0.1 0.0 0.0 10.6 11.1 0.3 0.2 0.7 0.2 0.2 1.3 1.4 0.6 0.2 0.0 3.1 0.8 65.9 5.0 0.4 0.0 0.0 0.7 0.5 0.8 0.3 EFHC1 "EJM, EJM1, FLJ10466, POC9, RIB72" ENSG00000096093 "EF-hand domain containing 1" Q5JVL4 6 52362123-52529886 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "fallopian tube: 34.6" "Cell type enhanced" "Detected in many" "Early spermatids: 242.0;Endometrial ciliated cells: 227.5;Respiratory ciliated cells: 529.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 6.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 25.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035307 Approved NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 49: Ciliated cells - Cilium organization" "HPA035307: AB_2674561" "unprognostic (2.11e-1)" "unprognostic (5.22e-2)" "unprognostic (3.31e-1)" "unprognostic (3.43e-2)" "unprognostic (2.51e-1)" "unprognostic (4.03e-3)" "unprognostic (1.60e-4)" "unprognostic (2.53e-2)" "unprognostic (1.18e-1)" "unprognostic (1.44e-1)" "prognostic favorable (2.33e-4)" "unprognostic (3.04e-1)" "prognostic unfavorable (3.29e-4)" "unprognostic (5.83e-2)" "unprognostic (3.14e-1)" "unprognostic (6.53e-2)" "unprognostic (3.27e-1)" 4.4 3.9 4.4 1.9 6.6 3.6 5.4 4.9 5.8 8.8 24.6 5.4 2.1 6.8 6.7 3.3 34.6 3.6 3.8 4.4 4.5 5.6 2.5 6.5 2.4 8.1 8.3 7.3 4.5 5.6 15.5 3.6 5.2 5.6 3.3 21.7 5.1 3.8 2.1 5.7 3.9 3.4 5.6 3.4 4.2 17.6 5.2 2.0 9.3 1.3 2.0 4.7 5.4 6.7 3.5 3.9 9.3 6.4 9.0 15.3 1.8 4.1 10.6 5.5 8.6 2.4 4.1 1.5 9.0 6.8 10.5 3.6 2.7 7.6 7.1 0.8 3.3 1.4 11.0 3.3 6.2 1.5 1.6 7.3 4.2 7.8 7.2 25.9 11.7 1.7 3.1 2.4 8.4 3.1 1.7 2.3 2.8 2.7 1.5 2.3 5.1 1.9 7.4 1.3 18.5 5.2 1.0 1.8 8.4 11.8 6.5 1.6 3.8 4.0 5.3 1.5 3.2 2.1 2.8 2.7 11.2 0.5 7.3 0.7 0.6 1.5 0.7 0.2 0.3 3.8 0.3 0.6 1.4 3.9 0.3 0.6 2.0 1.5 0.3 6.1 0.2 0.4 4.4 6.6 4.9 5.8 4.4 4.5 8.1 8.3 5.2 5.6 5.2 6.7 14.5 6.4 14.9 32.7 24.2 18.1 36.0 49.5 53.5 23.1 31.3 19.2 4.5 17.2 44.7 42.3 60.5 12.6 10.2 9.9 0.0 18.8 242.0 227.5 19.0 15.0 25.0 6.5 25.6 8.0 17.8 27.1 14.3 15.3 8.2 22.6 17.5 5.6 7.8 13.5 26.3 14.9 69.2 10.6 14.5 73.8 28.3 6.9 16.0 14.0 8.8 10.9 20.6 22.1 23.8 11.0 15.9 22.2 13.8 17.4 24.8 6.9 529.7 47.5 32.9 29.3 21.3 93.5 22.8 13.2 12.1 4.5 9.0 28.8 10.1 27.8 EFNA1 "ECKLG, EPLG1, GMAN, LERK1, TNFAIP4" ENSG00000169242 "Ephrin A1" P20827 1 155127876-155134899 "Cancer-related genes, Predicted secreted proteins, RAS pathway related proteins" Angiogenesis "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 472.8" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 942.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "naive CD4 T-cell: 11.4;naive CD8 T-cell: 5.9" "Lineage enriched" "Detected in single" 23 "T-cells: 11.4" "Cell line enhanced" "Detected in many" "BEWO: 266.5;HaCaT: 95.5;SiHa: 156.9;SK-BR-3: 227.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069549 Approved "Secreted to blood" NA Yes 2800000 "Cluster 32: T-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA069549: " "unprognostic (5.14e-2)" "unprognostic (3.04e-3)" "unprognostic (5.03e-2)" "unprognostic (2.01e-1)" "unprognostic (1.59e-1)" "unprognostic (2.47e-2)" "unprognostic (1.78e-2)" "unprognostic (5.80e-3)" "unprognostic (1.53e-1)" "unprognostic (4.56e-2)" "unprognostic (2.00e-2)" "unprognostic (2.23e-1)" "unprognostic (4.44e-2)" "unprognostic (3.58e-1)" "unprognostic (1.93e-1)" "unprognostic (2.41e-1)" "unprognostic (1.32e-1)" 43.2 24.0 25.6 4.9 30.0 1.3 64.7 27.2 33.9 31.7 21.8 42.5 57.9 23.7 28.5 54.7 23.2 24.5 47.1 25.5 25.9 73.8 472.8 86.7 8.1 31.0 29.0 17.5 53.6 29.7 19.5 109.9 29.8 79.5 51.6 7.8 66.6 22.1 18.5 123.1 69.3 13.4 27.8 8.6 40.7 4.1 27.6 21.0 79.9 38.6 12.5 36.9 55.5 35.2 15.1 5.9 0.9 11.5 2.1 0.1 266.5 0.0 0.5 0.2 0.3 13.9 32.0 0.0 26.3 0.0 9.0 95.5 6.6 35.3 0.2 9.8 2.2 0.1 19.0 76.1 0.9 0.2 1.5 4.9 84.5 0.0 30.2 7.3 53.6 0.9 2.8 0.3 0.0 52.2 0.3 1.1 1.7 52.3 17.7 6.1 1.5 9.3 66.4 22.4 9.8 14.2 156.9 227.1 6.0 48.8 51.1 0.0 6.7 0.1 9.1 0.6 1.5 2.3 0.5 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.2 0.0 1.0 0.7 0.0 0.3 11.4 5.9 0.4 0.4 0.0 0.0 0.0 1.6 25.6 30.0 27.2 33.9 25.5 25.9 31.0 29.0 29.8 27.8 27.6 35.2 116.8 198.7 113.1 0.7 2.3 127.7 103.7 91.6 327.8 3.0 198.3 151.9 47.8 95.8 101.2 18.4 0.0 195.6 4.4 265.0 13.7 130.1 0.3 100.4 19.1 148.9 18.6 4.0 0.7 63.9 942.6 23.2 124.9 163.5 6.3 0.1 106.4 133.2 28.2 5.0 0.8 114.1 101.7 4.3 19.5 0.7 4.7 4.2 62.2 2.8 0.6 5.7 0.0 3.5 28.7 73.9 205.5 0.4 4.1 197.8 238.6 34.5 54.5 1.1 0.0 6.5 35.9 0.8 2.6 253.2 217.8 254.2 7.5 1.3 95.9 135.9 EHD1 "FLJ42622, FLJ44618, H-PAST, HPAST1, PAST1" ENSG00000110047 "EH domain containing 1" Q9H4M9 11 64851642-64888296 "Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 151.6;testis: 159.9" "Group enriched" "Detected in all" 10 "Early spermatids: 1033.0;Late spermatids: 1950.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049890, HPA049986, HPA066751, HPA067747" Approved Supported "Plasma membrane" NA NA 10000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 2: Karpas-707 - Immune response" "Cluster 34: Spermatids - Unknown function" "Plasma membrane" "HPA049890: AB_2680936, HPA049986: AB_2680983, HPA066751: AB_2685713, HPA067747: AB_2685896" "unprognostic (1.51e-1)" "unprognostic (3.21e-1)" "unprognostic (6.35e-3)" "unprognostic (2.43e-1)" "unprognostic (1.62e-1)" "unprognostic (1.44e-1)" "prognostic unfavorable (2.81e-5)" "unprognostic (1.46e-3)" "unprognostic (9.10e-3)" "unprognostic (9.44e-2)" "unprognostic (2.11e-2)" "unprognostic (1.79e-1)" "unprognostic (1.27e-1)" "unprognostic (6.37e-2)" "unprognostic (9.88e-2)" "unprognostic (2.74e-1)" "unprognostic (2.59e-2)" 39.7 25.4 21.5 59.7 26.6 151.6 21.8 38.6 32.6 26.2 18.2 32.3 33.8 28.1 8.4 26.0 27.0 25.0 39.3 24.9 26.8 31.2 22.0 44.7 65.6 32.7 28.2 13.6 11.1 8.9 7.0 35.4 29.9 18.8 14.5 3.0 16.6 20.9 32.1 34.4 38.5 28.3 31.0 74.4 29.3 159.9 30.5 28.9 19.3 31.5 50.3 55.3 23.0 33.4 109.4 74.1 26.2 28.9 31.2 50.2 15.4 108.2 97.4 89.5 51.8 96.5 66.2 142.0 37.8 129.9 76.5 86.6 27.3 108.9 34.5 89.5 15.2 94.8 37.1 49.1 36.8 30.9 24.6 22.8 22.9 138.7 43.2 40.6 89.8 27.6 39.6 243.8 68.7 57.8 62.5 51.4 17.5 27.5 95.9 24.8 83.5 49.9 84.5 35.7 18.6 16.6 60.8 109.3 48.6 29.5 149.2 21.8 127.9 39.6 35.4 106.0 52.6 100.2 48.5 112.1 103.3 40.1 22.0 18.0 13.9 99.6 39.0 16.1 39.2 24.0 27.3 33.8 7.2 18.2 16.2 23.1 57.1 25.4 33.7 8.7 31.8 30.7 21.5 26.6 38.6 32.6 24.9 26.8 32.7 28.2 29.9 31.0 30.5 33.4 31.2 76.9 30.3 4.2 46.0 67.3 52.8 39.4 17.6 3.8 28.8 24.8 29.2 18.6 22.9 14.7 2.1 88.6 76.5 75.9 7.9 29.4 1033.0 41.9 24.4 29.3 6.6 19.8 1.7 40.8 24.5 32.4 25.5 54.9 93.8 37.2 10.4 10.9 32.2 5.0 3.5 27.7 12.2 37.4 61.0 1950.6 30.1 79.6 26.6 1.9 34.3 5.9 78.2 2.5 12.2 101.5 47.7 27.1 50.8 28.2 38.9 41.9 16.5 2.8 78.9 47.9 53.5 55.0 27.4 19.9 49.2 137.0 71.7 19.8 22.1 42.7 EHD4 PAST4 ENSG00000103966 "EH domain containing 4" Q9H223 15 41895933-41972557 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 189.5;Urothelial cells: 200.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 103.8;TIME: 172.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049890, HPA049986, HPA052729, HPA066751" Approved Approved "Plasma membrane" NA NA 440000 "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 10: Non-specific - Unknown function" "Plasma membrane" "HPA049890: AB_2680936, HPA049986: AB_2680983, HPA052729: AB_2681928, HPA066751: AB_2685713" "unprognostic (1.45e-1)" "unprognostic (1.37e-1)" "unprognostic (4.34e-3)" "unprognostic (3.36e-2)" "unprognostic (3.46e-2)" "unprognostic (4.48e-3)" "unprognostic (1.52e-1)" "unprognostic (3.36e-3)" "unprognostic (2.25e-1)" "unprognostic (3.74e-1)" "unprognostic (6.93e-2)" "unprognostic (2.35e-1)" "unprognostic (5.05e-2)" "unprognostic (3.49e-2)" "unprognostic (3.19e-2)" "unprognostic (8.27e-2)" "unprognostic (2.72e-1)" 21.6 4.6 3.1 11.8 3.2 10.9 16.4 7.5 3.5 9.4 5.3 12.1 5.5 9.6 10.5 15.0 9.8 15.2 27.8 3.3 3.8 14.3 9.6 15.0 12.8 4.8 4.0 5.6 14.3 12.8 5.8 8.3 4.8 9.5 10.2 6.1 10.4 9.7 4.4 14.3 12.4 12.9 5.2 7.4 9.9 2.8 4.0 5.3 18.4 4.7 8.8 23.8 9.0 6.6 28.7 9.8 9.3 9.6 4.6 6.5 8.1 14.9 31.4 25.9 36.1 41.4 16.1 5.9 39.2 18.8 51.6 28.4 13.9 32.6 19.0 35.7 11.7 8.7 13.5 7.1 11.3 4.0 24.4 5.5 12.6 26.3 28.8 9.9 103.8 8.7 9.2 6.6 21.1 12.2 4.2 4.5 7.1 27.8 33.5 0.1 24.5 9.4 23.4 57.0 15.4 6.5 10.9 23.2 17.0 9.0 22.9 5.6 172.8 8.1 15.7 30.5 73.1 18.1 30.9 12.4 10.3 9.4 71.6 1.1 14.0 9.0 4.0 12.4 6.1 2.1 6.2 5.0 14.9 2.6 2.6 3.8 2.3 4.4 5.2 2.5 7.9 8.0 3.1 3.2 7.5 3.5 3.3 3.8 4.8 4.0 4.8 5.2 4.0 6.6 94.9 6.4 44.2 3.9 20.0 81.6 189.5 68.1 34.1 4.9 31.4 20.1 36.6 30.0 69.0 44.1 31.3 10.1 22.2 96.0 7.9 71.3 16.1 66.1 9.7 114.9 22.6 5.7 1.2 62.6 20.4 21.3 25.5 72.4 61.6 16.2 54.7 8.7 89.0 1.7 0.7 22.5 28.5 35.6 52.7 34.7 7.5 46.3 19.6 12.2 53.5 37.5 4.1 26.7 2.7 75.1 70.9 4.9 31.5 49.9 71.4 4.6 60.8 27.8 13.1 8.0 29.0 5.4 8.2 29.3 79.8 17.4 27.8 21.2 37.3 200.1 EID3 "FLJ25832, NSE4B, NSMCE4B" ENSG00000255150 "EP300 interacting inhibitor of differentiation 3" Q8N140 12 104303739-104305205 "Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "testis: 61.2" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 78.5;Early spermatids: 72.8;Spermatocytes: 306.8" "Cancer enhanced" "Detected in many" "testis cancer: 5.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A549: 9.1;BJ: 8.5;BJ hTERT+: 6.9;BJ hTERT+ SV40 Large T+ RasG12V: 6.8;HeLa: 8.9" "Not detected" "Not detected" HPA059367 Uncertain Supported Nucleoplasm,Nucleoli NA NA "Cluster 15: NK-cells - Transcription" "Cluster 83: Testis - Spermatogenesis" "Cluster 20: HeLa - Mitochondria" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Nucleoli" "HPA059367: AB_2683992" "unprognostic (1.25e-1)" "unprognostic (5.41e-3)" "unprognostic (5.82e-2)" "unprognostic (8.21e-2)" "prognostic unfavorable (1.14e-4)" "unprognostic (8.02e-2)" "unprognostic (5.88e-5)" "unprognostic (1.06e-1)" "unprognostic (1.31e-1)" "unprognostic (1.66e-2)" "unprognostic (5.38e-3)" "unprognostic (1.18e-1)" "prognostic unfavorable (5.96e-5)" "unprognostic (8.70e-2)" "unprognostic (3.54e-1)" "unprognostic (2.04e-3)" "unprognostic (2.87e-2)" 2.8 3.1 1.8 3.5 1.7 5.3 2.4 2.1 2.2 3.2 2.8 3.1 0.8 2.7 2.7 1.8 3.1 2.7 2.0 1.9 2.4 1.8 1.4 3.0 6.2 6.6 3.1 4.1 2.5 1.2 3.7 1.7 2.2 3.3 0.9 6.6 1.4 5.5 0.6 2.7 2.7 2.3 1.6 3.0 2.2 61.2 2.4 3.7 1.5 0.9 3.9 2.4 2.1 2.0 0.3 9.1 0.3 0.9 2.0 2.0 1.7 8.5 6.9 4.0 6.8 0.2 0.5 0.1 0.0 1.9 1.8 0.2 0.3 0.7 5.9 0.5 0.1 1.7 8.9 1.4 2.9 0.1 0.5 2.7 0.0 2.5 0.5 0.4 0.6 0.4 0.1 0.5 2.5 0.1 3.1 1.3 0.4 0.1 1.8 0.2 0.0 0.1 2.2 0.3 0.1 0.0 5.6 0.4 0.2 0.2 0.0 0.0 1.3 0.1 0.3 2.0 0.4 0.4 0.2 0.1 0.2 0.0 0.9 0.0 0.3 0.5 4.4 1.4 4.6 2.3 5.6 5.4 0.2 2.3 7.9 5.0 0.7 6.2 0.9 0.5 7.3 2.2 1.8 1.7 2.1 2.2 1.9 2.4 6.6 3.1 2.2 1.6 2.4 2.0 4.7 0.0 6.0 0.0 5.9 13.4 78.5 5.9 1.8 4.9 2.4 3.9 1.4 2.8 2.7 1.8 27.1 2.4 11.1 2.4 0.0 3.5 72.8 13.8 9.6 14.0 0.0 6.6 0.0 1.3 1.6 12.7 5.1 21.1 1.3 6.1 5.3 3.0 1.9 11.8 0.0 1.2 4.1 4.7 26.8 23.5 8.7 6.8 1.8 0.0 4.0 7.5 6.2 0.0 0.0 4.9 4.5 4.5 4.3 47.6 1.2 1.7 7.5 18.6 6.6 7.6 8.4 306.8 44.3 1.4 7.7 2.5 11.1 15.6 1.0 46.9 EIF2AK3 "PEK, PERK" ENSG00000172071 "Eukaryotic translation initiation factor 2 alpha kinase 3" Q9NZJ5 2 88556741-88627464 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Stress response, Translation regulation, Unfolded protein response" "Kinase, Serine/threonine-protein kinase, Transferase" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 19.6" "Cell type enhanced" "Detected in many" "Plasma cells: 121.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "naive B-cell: 1.9" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Daudi: 46.8;U-266/70: 44.0;U-698: 31.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009204, HPA015737" Approved NA NA "Cluster 24: B-cells - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "CAB009204: AB_2230863, HPA015737: AB_1848062" "unprognostic (7.25e-3)" "unprognostic (5.35e-2)" "unprognostic (3.03e-3)" "unprognostic (9.32e-2)" "unprognostic (9.39e-3)" "unprognostic (3.25e-2)" "unprognostic (2.27e-2)" "unprognostic (3.46e-3)" "unprognostic (9.84e-2)" "unprognostic (3.50e-1)" "unprognostic (1.89e-1)" "unprognostic (2.31e-1)" "unprognostic (2.06e-1)" "unprognostic (2.92e-1)" "unprognostic (9.80e-2)" "unprognostic (3.60e-3)" "unprognostic (2.90e-3)" 3.3 3.1 0.8 4.0 1.1 2.6 1.6 1.6 1.4 2.3 1.6 4.7 6.2 1.9 1.0 1.6 1.3 1.4 1.5 0.8 1.5 2.0 1.9 1.8 3.2 1.0 1.2 1.9 19.6 3.4 1.1 3.2 0.9 4.0 1.8 0.1 9.7 1.2 2.0 1.4 5.0 0.9 1.5 3.1 12.3 1.0 1.2 1.3 3.5 0.0 2.3 1.9 1.8 2.1 8.7 3.3 1.2 4.3 2.8 2.0 15.9 12.4 1.1 0.7 2.1 3.5 2.9 46.8 8.0 1.3 3.1 7.2 1.6 1.3 1.1 25.3 7.1 4.6 1.7 2.0 1.1 3.9 12.3 0.1 1.5 0.7 2.0 0.8 1.4 4.9 3.0 8.7 0.6 4.4 5.5 2.2 6.2 2.7 7.2 25.1 7.0 8.2 1.3 5.0 5.6 9.9 6.3 6.5 8.2 1.7 2.2 4.4 3.9 2.5 5.5 10.8 7.1 44.0 24.4 31.0 4.6 4.2 6.2 0.0 0.1 0.1 0.3 0.0 0.2 1.0 0.2 0.8 0.1 1.9 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.8 1.1 1.6 1.4 0.8 1.5 1.0 1.2 0.9 1.5 1.2 2.1 9.2 9.6 7.5 14.7 43.8 20.3 8.9 7.2 26.7 8.4 14.7 8.9 8.2 17.2 7.2 12.9 8.4 4.1 13.4 14.0 0.0 3.7 0.1 18.4 18.3 7.6 13.7 1.7 31.3 6.5 6.9 15.2 40.2 39.2 1.3 4.4 8.9 11.8 4.6 1.7 39.0 30.1 14.2 5.1 41.2 0.7 7.5 27.7 32.0 21.5 3.9 3.0 9.2 20.1 26.2 7.0 7.7 5.7 121.3 13.0 5.4 2.9 7.7 2.3 0.0 13.4 9.4 3.1 3.6 23.8 18.3 6.7 12.8 3.5 6.8 16.6 EIF2S1 "EIF-2alpha, EIF2, EIF2A" ENSG00000134001 "Eukaryotic translation initiation factor 2 subunit alpha" P05198 14 67360328-67386516 "Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis, Translation regulation" "Initiation factor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011663, HPA064885" Supported Enhanced Cytosol NA NA 210000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "CAB011663: AB_2096478, HPA064885: AB_2685382" "unprognostic (1.86e-2)" "unprognostic (8.33e-2)" "unprognostic (4.31e-2)" "unprognostic (2.46e-2)" "unprognostic (3.78e-2)" "unprognostic (1.78e-3)" "prognostic unfavorable (4.73e-7)" "unprognostic (4.14e-3)" "unprognostic (4.49e-1)" "unprognostic (1.68e-2)" "prognostic unfavorable (4.97e-4)" "unprognostic (2.95e-1)" "unprognostic (1.21e-2)" "unprognostic (1.73e-1)" "unprognostic (4.65e-1)" "unprognostic (1.59e-2)" "prognostic unfavorable (7.11e-4)" 28.3 24.5 12.5 29.9 14.0 25.0 25.7 15.1 17.8 18.1 10.4 25.0 21.5 19.4 19.6 38.8 15.8 21.5 28.7 14.6 14.1 24.5 35.3 18.4 30.4 13.7 12.7 17.1 26.3 22.9 9.4 26.3 13.6 22.1 26.7 21.2 18.3 22.3 49.4 23.7 21.5 27.0 13.8 19.8 19.8 33.4 13.5 27.9 27.9 40.6 33.5 39.1 19.0 16.6 265.7 86.4 59.8 92.3 56.4 63.4 127.8 115.5 68.3 127.4 110.7 101.6 92.2 118.7 57.0 87.4 85.7 100.4 139.1 110.3 192.7 86.9 51.9 76.9 80.0 70.4 59.2 82.7 71.9 52.4 62.6 113.9 172.5 49.8 105.4 73.8 132.6 89.6 127.3 131.3 113.7 64.7 61.1 157.9 142.9 85.7 99.0 84.6 78.2 120.0 85.9 60.7 83.0 96.5 91.1 52.3 164.5 70.8 81.3 167.4 180.7 82.0 124.4 77.0 90.4 180.7 97.1 145.3 110.2 51.4 50.6 33.0 47.4 71.0 58.4 55.4 54.5 51.7 70.1 45.8 50.3 51.5 6.9 58.6 62.8 48.0 64.3 70.7 12.5 14.0 15.1 17.8 14.6 14.1 13.7 12.7 13.6 13.8 13.5 16.6 64.1 28.9 40.2 17.3 44.1 142.8 88.2 77.2 37.5 22.1 32.0 30.1 92.8 30.0 55.8 22.0 12.5 78.7 38.0 23.3 70.5 89.6 81.0 34.6 48.9 60.3 13.1 64.2 21.7 63.0 104.7 51.2 34.1 44.8 35.5 35.7 26.4 39.8 70.4 37.0 20.9 30.6 61.1 37.9 51.3 33.4 31.1 40.7 51.6 15.9 61.3 32.2 36.0 15.1 23.8 70.8 18.3 40.6 56.7 79.9 26.6 65.1 35.0 35.2 26.3 60.7 85.9 204.9 96.3 49.7 130.4 93.4 46.1 57.9 39.7 79.1 EIF4E1B FLJ36951 ENSG00000175766 "Eukaryotic translation initiation factor 4E family member 1B" A6NMX2 5 176630618-176646644 "Predicted intracellular proteins" "Protein biosynthesis, Translation regulation" "Initiation factor, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 3.1;epididymis: 1.1;retina: 2.7" "Group enriched" "Detected in some" 6 "Bipolar cells: 8.5;Cardiomyocytes: 12.8;Cone photoreceptor cells: 16.7;Excitatory neurons: 7.1;Horizontal cells: 11.8;Inhibitory neurons: 8.4;Rod photoreceptor cells: 17.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 7 "T-47d: 3.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA045045 Approved NA NA "Cluster 58: Brain - Synaptic function" "Cluster 6: T47d - Mammary gland" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA045045: AB_2679197" "unprognostic (6.54e-2)" "unprognostic (1.53e-2)" "unprognostic (7.44e-2)" "unprognostic (5.26e-2)" "unprognostic (1.86e-1)" 0.0 0.2 1.1 0.0 1.4 0.2 0.0 1.5 3.1 0.0 0.3 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 1.3 0.8 0.0 0.0 0.0 0.1 1.1 0.9 0.0 0.0 0.0 0.4 0.0 1.1 0.0 0.0 2.7 0.0 0.0 0.0 0.1 0.1 0.0 0.6 0.0 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 1.4 1.5 3.1 1.3 0.8 1.1 0.9 1.1 0.6 0.7 1.9 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 8.5 0.0 0.0 12.8 0.0 0.0 0.0 16.7 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 7.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.8 8.4 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.8 0.0 1.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 EIF4H "KIAA0038, WBSCR1, WSCR1" ENSG00000106682 "Eukaryotic translation initiation factor 4H" Q15056 7 74174231-74197122 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis" "Initiation factor, RNA-binding" "Cancer-related genes, Williams-Beuren syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 990.0;Late spermatids: 2765.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030542 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 750000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "Nucleoplasm, Nuclear bodies" "HPA030542: AB_10601368" "unprognostic (2.83e-1)" "unprognostic (9.50e-2)" "unprognostic (2.36e-1)" "unprognostic (1.50e-2)" "prognostic unfavorable (3.89e-4)" "prognostic unfavorable (2.15e-4)" "unprognostic (1.61e-2)" "unprognostic (2.72e-3)" "unprognostic (1.79e-1)" "unprognostic (2.99e-2)" "unprognostic (1.72e-2)" "unprognostic (2.52e-1)" "unprognostic (1.07e-2)" "unprognostic (3.04e-1)" "unprognostic (2.23e-1)" "unprognostic (5.68e-2)" "unprognostic (1.27e-2)" 186.9 174.9 151.0 117.8 159.3 283.3 168.3 163.8 157.3 179.8 129.6 208.4 130.2 186.4 76.6 249.3 163.6 100.0 171.0 149.9 151.9 156.6 197.0 158.4 130.3 161.9 156.9 181.2 226.4 160.7 119.9 162.8 162.2 150.3 100.2 149.8 170.1 125.1 399.8 230.9 148.9 119.2 165.2 137.4 192.9 79.9 164.6 150.2 141.2 173.4 137.2 175.3 179.7 187.1 526.3 341.4 251.3 303.1 220.8 231.8 283.4 359.8 276.3 300.3 289.5 423.3 388.6 444.3 96.6 338.8 424.2 266.6 280.5 481.5 286.3 298.0 329.2 247.5 305.2 345.9 253.1 429.0 236.9 273.2 300.8 326.2 460.7 341.5 326.8 260.1 445.8 186.4 305.2 448.2 342.0 516.8 337.6 430.3 328.9 386.9 342.7 401.5 250.9 324.7 252.7 325.4 340.9 420.3 296.0 331.3 476.8 272.4 340.2 411.6 284.6 345.1 474.4 218.8 299.8 771.4 326.3 435.1 441.4 213.7 229.7 245.6 156.9 255.6 164.5 146.4 161.4 158.3 224.2 132.9 183.9 151.7 150.1 193.5 270.2 95.1 194.7 388.0 151.0 159.3 163.8 157.3 149.9 151.9 161.9 156.9 162.2 165.2 164.6 187.1 105.8 83.3 81.2 15.7 97.1 119.2 153.8 101.5 78.0 93.1 103.0 95.5 43.3 68.6 68.7 44.1 25.0 198.8 91.9 98.7 107.6 148.1 990.0 104.8 98.3 103.0 90.4 79.5 25.3 157.7 381.4 101.6 61.2 112.5 122.4 112.1 79.6 95.7 124.2 97.6 24.6 87.2 91.6 101.2 102.7 2765.8 103.8 86.8 72.9 15.9 157.4 134.7 119.4 16.6 44.2 147.0 82.8 110.6 82.7 140.7 84.6 69.0 57.8 72.3 85.5 107.3 117.7 61.2 64.6 90.1 116.1 395.3 92.4 116.9 109.5 140.4 EIF5AL1 "bA342M3.3, EIF5AP1" ENSG00000253626 "Eukaryotic translation initiation factor 5A like 1" Q6IS14 10 79512533-79516440 "Predicted intracellular proteins, Transporters" "mRNA transport, Protein biosynthesis, Protein transport, Translocation, Transport" "Elongation factor, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "testis: 10.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 79.2;Intestinal goblet cells: 96.7;Spermatocytes: 76.5;Undifferentiated cells: 121.3" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "U-251 MG: 2.2" HPA074052 Approved "Plasma membrane,Cytosol" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "Plasma membrane" "HPA074052: " "unprognostic (2.16e-2)" "prognostic favorable (4.23e-4)" "unprognostic (2.55e-1)" "unprognostic (4.14e-3)" "unprognostic (1.50e-1)" "unprognostic (3.48e-2)" "unprognostic (4.25e-2)" "unprognostic (2.50e-3)" "unprognostic (2.04e-2)" "unprognostic (3.57e-1)" "unprognostic (1.01e-1)" "unprognostic (8.79e-3)" "unprognostic (1.56e-1)" "unprognostic (8.63e-2)" "unprognostic (1.87e-1)" "unprognostic (6.68e-2)" "unprognostic (1.81e-1)" 0.8 0.8 0.1 0.2 0.1 0.2 0.6 0.5 0.3 0.4 0.0 0.6 0.2 0.5 0.2 1.4 0.4 0.0 0.9 0.1 0.0 0.5 1.3 0.6 0.3 0.0 0.0 0.3 0.7 0.2 0.4 0.0 0.0 0.5 0.2 0.8 0.5 0.0 1.5 1.0 0.5 0.0 0.0 0.5 0.5 10.6 0.0 0.0 0.5 0.0 0.3 0.5 0.7 0.1 0.4 0.8 0.3 1.7 0.0 0.2 0.3 0.3 0.1 0.3 0.2 0.6 0.3 0.9 0.3 0.0 0.2 0.5 0.1 0.0 0.2 0.2 0.7 0.2 1.0 0.4 0.1 0.3 0.6 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.2 0.3 0.1 0.6 1.0 0.9 1.2 0.1 0.1 0.3 0.7 0.6 0.5 0.8 0.2 0.5 0.5 0.4 0.6 0.1 0.8 0.7 0.2 0.4 1.0 1.1 2.2 0.4 0.5 0.8 0.7 0.2 0.6 1.1 0.8 0.6 1.2 2.0 1.4 1.3 1.2 1.3 1.6 1.3 0.9 1.3 0.7 1.7 1.3 2.5 1.0 0.8 0.1 0.1 0.5 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.8 16.0 30.0 1.3 10.4 33.8 3.0 7.8 0.0 0.6 5.1 2.4 43.1 2.8 16.1 0.0 0.0 20.8 2.4 79.2 11.7 64.5 14.7 2.9 4.4 12.9 60.0 10.7 0.6 47.8 35.1 15.5 0.0 3.2 48.2 0.9 4.2 5.1 17.5 1.7 0.6 96.7 8.2 8.7 27.9 8.7 5.0 7.2 19.6 0.0 41.9 1.2 13.4 0.0 1.0 65.6 61.2 3.0 0.5 10.3 66.5 11.1 6.1 0.5 0.0 6.9 25.9 76.5 4.3 0.0 34.5 27.6 8.9 3.3 121.3 5.0 ELF2 "EU32, NERF, NERF-1A, NERF-1B, NERF-2" ENSG00000109381 "E74 like ETS transcription factor 2" Q15723 4 139028112-139177218 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 279.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006057, HPA071166" Enhanced Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 29: U-266 - Adaptive immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm "Nuclear bodies" "HPA006057: AB_1078733, HPA071166: AB_2686351" "unprognostic (7.21e-2)" "unprognostic (3.84e-2)" "unprognostic (7.41e-2)" "unprognostic (3.72e-2)" "unprognostic (2.29e-1)" "unprognostic (2.80e-2)" "unprognostic (1.49e-1)" "unprognostic (2.43e-2)" "unprognostic (7.05e-3)" "unprognostic (1.67e-1)" "unprognostic (5.73e-2)" "unprognostic (2.21e-2)" "unprognostic (2.48e-2)" "unprognostic (3.65e-1)" "unprognostic (3.47e-1)" "unprognostic (1.31e-1)" "unprognostic (4.97e-3)" 23.7 14.2 12.1 15.2 17.3 47.3 24.5 19.2 16.1 21.8 9.6 24.6 15.0 24.7 18.5 17.3 20.7 17.8 20.1 11.1 15.6 15.5 20.4 19.0 19.9 15.6 14.9 28.2 16.7 20.0 22.6 26.8 15.9 21.5 19.2 30.7 21.4 21.7 36.0 23.2 17.6 23.0 13.2 19.6 17.4 37.4 14.5 32.8 23.0 33.6 21.4 19.2 18.4 20.2 15.9 11.3 27.9 21.4 28.2 31.7 26.9 18.4 31.8 19.6 21.8 22.2 31.2 32.3 18.5 25.7 10.4 16.8 41.2 26.3 20.5 20.2 18.6 28.5 26.4 20.0 20.7 32.1 22.1 31.1 24.8 19.3 23.3 25.7 29.5 18.0 46.8 18.4 17.7 27.8 37.8 28.6 17.0 36.4 13.1 36.0 36.8 30.1 25.1 27.2 28.4 32.6 23.1 28.5 17.6 32.4 19.7 38.5 25.0 18.3 15.9 16.7 12.4 40.8 48.6 28.3 13.5 32.4 17.2 13.3 8.3 14.1 12.0 7.2 13.2 17.5 11.8 10.8 9.9 19.3 14.6 13.5 9.1 12.9 7.9 18.0 9.4 5.3 12.1 17.3 19.2 16.1 11.1 15.6 15.6 14.9 15.9 13.2 14.5 20.2 103.0 48.1 22.5 64.0 57.6 53.2 41.1 36.1 120.1 42.0 50.3 40.4 37.0 40.0 39.1 40.5 75.0 32.6 71.9 31.0 43.0 26.4 26.0 60.0 54.3 67.1 47.3 43.5 73.6 24.2 32.3 63.7 35.7 56.3 34.8 44.0 53.2 46.9 22.2 67.3 75.3 38.1 42.7 52.2 40.1 24.6 52.5 59.5 30.2 98.4 49.2 37.3 77.2 83.9 279.4 24.1 33.5 38.0 51.0 52.6 35.9 23.1 48.2 57.7 39.5 81.4 59.2 59.7 42.0 79.0 47.6 23.7 50.7 33.6 27.7 39.6 ELFN1 PPP1R28 ENSG00000225968 "Extracellular leucine rich repeat and fibronectin type III domain containing 1" P0C7U0 7 1688119-1747954 "Predicted membrane proteins" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 7.2;liver: 14.5" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 6.2;Endothelial cells: 5.7;Hepatic stellate cells: 7.1;Hepatocytes: 13.5;Inhibitory neurons: 19.2;Rod photoreceptor cells: 7.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "REH: 31.2;U-138 MG: 18.5;U-2 OS: 27.0;U-2197: 32.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA066382 Approved "Nucleoplasm,Cell Junctions" NA NA 43000 "Cluster 15: Liver - Metabolism" "Cluster 18: U-2197 - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Cell Junctions" "HPA066382: AB_2732744" "unprognostic (8.45e-2)" "unprognostic (3.39e-3)" "unprognostic (6.54e-4)" "unprognostic (1.64e-1)" "unprognostic (1.30e-1)" "unprognostic (1.44e-1)" "prognostic favorable (9.68e-4)" "unprognostic (4.60e-3)" "unprognostic (1.63e-3)" "unprognostic (6.60e-2)" "unprognostic (4.14e-3)" "unprognostic (1.11e-2)" "unprognostic (2.31e-2)" "unprognostic (7.47e-3)" "unprognostic (8.63e-2)" "unprognostic (2.78e-1)" "unprognostic (4.07e-1)" 3.1 0.4 1.5 0.3 2.5 0.0 1.5 1.0 3.4 4.2 0.0 0.6 0.1 2.9 0.1 0.5 1.5 0.4 4.6 1.0 4.4 3.9 14.5 0.6 0.1 3.2 4.6 0.4 0.6 0.1 0.8 0.4 3.2 1.0 0.0 3.0 0.4 0.1 0.7 1.0 0.8 0.2 7.2 1.1 0.6 0.8 2.6 0.7 0.8 0.4 0.0 0.6 1.7 0.8 0.3 0.0 4.6 9.7 0.0 1.4 0.0 1.6 0.0 0.0 0.0 0.1 0.5 0.0 4.6 2.1 0.7 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.1 0.6 0.0 0.0 0.8 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 5.7 0.0 4.7 1.9 0.0 1.1 31.2 0.0 3.1 0.0 0.0 4.3 2.0 0.3 0.2 0.0 0.5 0.1 0.3 0.1 18.5 27.0 32.1 0.0 0.0 0.4 8.3 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 2.5 1.0 3.4 1.0 4.4 3.2 4.6 3.2 7.2 2.6 0.8 4.8 0.0 0.6 0.0 0.0 0.1 0.3 0.3 2.8 1.3 0.1 0.3 1.8 0.0 0.0 0.0 6.2 0.0 0.0 0.0 3.9 0.1 0.1 0.3 2.0 5.7 0.0 0.0 0.8 0.0 0.0 1.3 0.0 0.1 0.0 0.0 7.1 13.5 0.1 0.0 19.2 0.0 0.0 0.6 0.7 0.1 0.9 0.1 1.8 1.0 0.0 0.9 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 7.8 0.0 0.0 0.9 0.0 2.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 ELK1 ENSG00000126767 "ETS transcription factor ELK1" P19419 X 47635521-47650604 "Predicted intracellular proteins, RAS pathway related proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Granulosa cells: 251.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003808, HPA036084, HPA064381" Enhanced Enhanced Nucleoplasm NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 10: Brain - Neuronal signaling" "Cluster 16: U-266 - Nucleosome" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "CAB003808: AB_562282, HPA036084: AB_2674931, HPA064381: AB_2685250" "unprognostic (2.25e-1)" "unprognostic (1.83e-2)" "unprognostic (4.77e-2)" "unprognostic (1.40e-2)" "unprognostic (2.31e-1)" "unprognostic (2.73e-1)" "unprognostic (1.16e-2)" "unprognostic (1.69e-1)" "unprognostic (1.47e-1)" "unprognostic (2.59e-3)" "unprognostic (1.17e-1)" "unprognostic (8.39e-2)" "prognostic unfavorable (3.25e-5)" "unprognostic (1.02e-1)" "unprognostic (2.03e-1)" "unprognostic (1.79e-2)" "unprognostic (1.67e-2)" 16.8 30.7 71.7 12.4 53.1 13.7 12.0 37.1 62.5 15.0 19.9 12.8 9.0 17.0 17.4 15.0 18.6 10.1 19.3 58.5 32.8 12.6 26.4 16.2 12.3 26.7 26.2 54.2 12.9 17.0 12.7 9.2 27.5 15.4 9.6 7.7 13.1 11.2 32.9 15.2 12.9 10.9 23.4 18.9 13.6 21.2 52.2 12.9 10.5 18.5 12.3 14.8 11.9 40.6 35.6 27.2 14.3 39.1 23.3 26.5 19.8 31.1 34.9 34.8 34.5 19.3 26.4 29.0 16.1 31.0 59.9 21.2 37.6 31.7 31.5 31.1 34.8 23.4 25.0 17.9 49.3 26.3 39.4 27.9 27.2 53.4 33.5 28.8 20.8 40.4 47.9 32.9 27.8 46.5 28.2 30.8 33.7 16.7 59.1 30.0 36.0 45.8 19.7 15.3 31.0 25.6 48.5 17.8 43.4 31.8 44.7 16.7 16.1 39.5 41.2 53.9 29.2 53.5 83.2 27.8 44.5 45.3 25.0 1.7 6.3 2.8 5.3 7.2 6.4 5.2 6.8 6.3 9.5 4.6 5.7 5.0 3.1 3.4 6.5 6.5 9.8 5.6 71.7 53.1 37.1 62.5 58.5 32.8 26.7 26.2 27.5 23.4 52.2 40.6 10.1 0.0 6.7 4.2 12.0 16.8 14.3 7.5 15.9 15.2 15.0 10.4 9.0 5.7 5.3 7.3 4.2 7.7 6.3 7.5 5.9 7.6 4.0 8.0 13.3 9.8 10.2 14.9 7.7 7.3 9.6 18.0 6.6 9.2 8.2 251.8 20.3 14.6 10.3 5.0 5.7 7.8 4.1 9.5 19.0 3.3 14.0 15.0 7.2 2.8 16.8 9.0 6.2 5.0 2.9 7.1 5.6 29.7 10.3 12.8 4.6 6.3 2.1 7.2 6.6 18.7 20.0 2.6 11.1 12.3 15.9 8.9 11.1 48.8 10.0 11.8 ELL "C19orf17, ELL1, Men, PPP1R68" ENSG00000105656 "Elongation factor for RNA polymerase II" P55199 19 18442663-18522116 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 297.2;Late spermatids: 235.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004202, HPA046076" Uncertain Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 29: U-266 - Adaptive immune response" "Cluster 34: Spermatids - Unknown function" Nucleoplasm "Nuclear bodies, Cytosol" "HPA004202: , HPA046076: AB_2679526" "unprognostic (9.49e-2)" "unprognostic (1.38e-1)" "unprognostic (3.26e-3)" "unprognostic (2.07e-1)" "unprognostic (1.64e-1)" "unprognostic (2.10e-1)" "unprognostic (8.26e-2)" "unprognostic (2.71e-1)" "unprognostic (2.34e-1)" "unprognostic (3.00e-2)" "unprognostic (6.28e-3)" "unprognostic (2.38e-2)" "unprognostic (1.57e-1)" "unprognostic (2.07e-1)" "unprognostic (5.12e-1)" "unprognostic (2.46e-1)" "unprognostic (1.06e-1)" 15.1 7.7 4.0 9.0 6.2 29.8 11.8 8.4 7.0 11.2 5.0 10.6 6.5 11.0 2.0 10.3 10.6 5.7 10.5 3.6 4.2 12.6 14.1 16.6 7.6 4.7 4.2 13.0 10.0 4.1 11.3 10.0 3.8 9.9 2.3 1.2 8.3 3.6 20.1 15.3 12.8 3.6 4.0 17.3 10.1 38.5 6.1 6.8 8.2 9.9 4.3 10.5 11.0 3.9 12.7 5.7 3.2 6.8 3.4 4.2 22.7 10.0 8.8 7.5 7.1 7.1 9.8 15.6 11.8 6.7 5.2 8.6 4.7 11.1 3.8 13.3 10.9 9.4 5.9 6.3 5.2 10.3 11.8 8.6 9.3 9.8 7.7 5.6 5.4 8.5 13.5 21.8 4.0 10.3 12.5 11.9 10.6 7.8 16.8 10.9 4.8 17.4 5.3 8.8 5.7 6.4 7.4 12.3 11.0 4.1 6.4 12.4 9.0 8.6 6.6 11.6 9.3 34.8 23.4 11.7 11.4 17.6 12.5 0.3 5.9 4.5 4.5 4.1 7.3 2.9 2.6 3.9 5.0 2.1 1.7 2.7 18.1 2.3 2.1 8.6 3.1 4.1 4.0 6.2 8.4 7.0 3.6 4.2 4.7 4.2 3.8 4.0 6.1 3.9 12.3 6.4 6.1 9.1 16.3 28.0 26.4 11.9 23.3 4.5 19.7 10.7 5.1 11.5 7.2 3.7 4.2 47.5 29.5 15.2 11.7 8.7 297.2 22.9 16.0 11.4 19.7 10.3 9.1 8.0 17.6 17.2 12.8 37.7 11.4 5.1 7.5 15.5 19.3 1.7 11.2 10.1 6.1 12.8 21.7 235.9 6.5 20.4 7.2 9.4 13.8 5.3 4.1 7.1 8.0 10.8 3.7 3.0 53.6 14.2 11.8 7.0 8.4 3.4 19.7 13.0 16.7 18.2 24.7 19.4 30.4 68.7 19.2 5.9 7.1 19.9 ELL3 FLJ22637 ENSG00000128886 "Elongation factor for RNA polymerase II 3" Q9HB65 15 43772605-43777315 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 57.7;skin 1: 25.0" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 5.2;Gastric mucus-secreting cells: 4.6;Proximal enterocytes: 6.5;Squamous epithelial cells: 21.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "memory B-cell: 10.5;naive B-cell: 15.9" "Lineage enriched" "Detected in many" 7 "B-cells: 15.9" "Cell line enhanced" "Detected in many" "Daudi: 73.8;OE19: 28.5;T-47d: 39.0;U-698: 149.9" "Region enriched" "Detected in single" 11 "olfactory bulb: 1.9" "Not detected" "Not detected" "HPA028938, HPA073494" Approved Supported "Nucleoplasm,Nucleoli,Mitotic chromosome" Yes NA "Cluster 37: B-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoplasm, Nucleoli" "Mitotic chromosome" "HPA028938: AB_10795352, HPA073494: " "unprognostic (2.59e-2)" "unprognostic (4.41e-1)" "unprognostic (1.76e-1)" "unprognostic (1.28e-1)" "unprognostic (3.59e-1)" "unprognostic (2.30e-2)" "unprognostic (1.17e-1)" "unprognostic (2.42e-3)" "unprognostic (1.52e-2)" "unprognostic (3.89e-1)" "unprognostic (2.19e-1)" "unprognostic (3.53e-1)" "unprognostic (1.87e-1)" "unprognostic (3.67e-2)" "unprognostic (8.95e-2)" "unprognostic (1.08e-1)" "unprognostic (1.24e-2)" 0.5 0.9 1.0 9.7 1.0 0.2 5.2 1.0 1.1 1.6 4.7 8.0 14.1 0.6 1.1 4.5 3.9 0.7 0.5 1.0 1.1 1.4 0.7 1.5 49.7 1.0 1.1 1.7 0.4 1.6 0.5 3.7 1.1 2.0 12.3 0.1 2.2 1.0 0.4 25.0 12.9 1.0 1.0 1.0 1.8 16.2 1.4 1.5 0.7 1.9 57.7 0.7 0.8 1.1 2.1 0.2 0.6 1.1 4.9 1.2 0.4 0.2 1.3 2.8 3.1 0.0 1.3 73.8 0.1 1.2 0.1 13.7 1.3 0.7 1.4 1.6 7.3 0.4 2.6 4.6 1.0 0.1 0.0 1.4 12.3 0.7 0.2 0.2 1.1 0.4 0.2 0.0 0.7 4.0 1.5 1.4 0.1 28.5 2.4 0.8 0.0 0.0 1.8 0.0 9.5 0.0 1.7 21.5 0.0 0.3 39.0 0.2 0.0 0.3 0.0 0.0 0.1 0.0 0.0 149.9 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.1 0.2 10.5 0.6 0.1 0.0 15.9 1.1 0.2 0.0 0.1 0.0 2.2 0.6 0.6 1.0 1.0 1.0 1.1 1.0 1.1 1.0 1.1 1.1 1.0 1.4 1.1 0.1 0.0 0.0 0.0 2.2 0.4 0.1 0.2 5.2 0.0 0.7 0.5 0.0 0.0 0.2 0.0 0.0 0.1 0.3 1.2 0.0 0.1 1.8 0.4 0.1 0.2 0.0 0.4 0.1 0.7 0.0 0.5 4.6 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 2.5 0.0 0.0 0.5 2.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.0 0.1 6.5 0.1 3.1 0.0 0.0 0.2 0.4 0.2 0.2 21.0 1.0 0.3 0.1 0.1 2.3 0.2 ELOB "SIII, TCEB2" ENSG00000103363 "Elongin B" Q15370 16 2771414-2777280 "Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 1279.6;Exocrine glandular cells: 911.2;Pancreatic endocrine cells: 1027.1;Proximal tubular cells: 1789.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064006 Approved NA NA 82000 "Cluster 2: Granulocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" "HPA064006: " "unprognostic (1.77e-1)" "unprognostic (5.27e-3)" "unprognostic (3.93e-1)" "unprognostic (1.50e-3)" "unprognostic (2.02e-1)" "unprognostic (2.28e-2)" "unprognostic (3.19e-1)" "unprognostic (1.27e-1)" "unprognostic (1.81e-2)" "unprognostic (4.05e-2)" "unprognostic (3.14e-1)" "unprognostic (7.15e-2)" "unprognostic (7.83e-2)" "unprognostic (3.42e-1)" "unprognostic (1.40e-1)" "unprognostic (1.06e-1)" "unprognostic (6.32e-2)" 234.7 293.3 355.3 130.9 359.6 289.7 235.0 363.3 479.4 217.1 339.1 275.5 141.6 214.1 80.8 297.1 217.7 180.2 485.0 365.8 363.9 301.6 340.1 206.6 185.6 356.8 360.3 187.8 207.5 203.4 279.9 109.8 358.2 233.8 83.2 51.4 332.2 112.9 573.1 254.5 203.5 89.5 362.8 208.8 255.6 428.5 366.5 154.6 199.4 266.2 93.4 220.1 228.6 367.5 185.8 559.0 254.5 407.0 263.5 354.6 265.7 233.1 242.6 254.3 210.0 408.8 372.6 288.6 309.4 256.7 275.1 206.6 146.4 403.4 61.9 349.4 593.0 188.5 773.6 578.7 410.1 276.9 286.6 362.8 517.3 242.4 180.6 254.7 225.8 420.1 258.4 465.0 265.5 1212.8 459.7 708.6 331.4 363.2 570.0 487.9 248.3 636.9 311.8 404.2 461.4 335.2 310.0 472.3 320.1 79.0 434.1 506.3 303.5 323.4 308.9 232.4 277.7 382.8 503.1 619.8 152.5 279.6 347.2 3022.8 1566.1 2928.2 711.2 1154.9 687.1 877.6 741.7 760.1 951.3 757.8 638.9 671.0 1519.2 892.1 1236.0 848.6 1046.2 2212.0 355.3 359.6 363.3 479.4 365.8 363.9 356.8 360.3 358.2 362.8 366.5 367.5 401.9 182.7 218.4 0.0 89.7 0.0 0.0 0.0 0.0 0.0 633.1 738.0 0.0 0.0 131.8 505.8 0.0 562.9 243.1 0.0 1279.6 752.8 0.0 641.0 734.0 188.1 0.0 0.0 0.0 911.2 689.1 219.6 0.0 551.8 107.2 339.5 0.0 0.0 719.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 304.4 0.0 0.0 419.2 0.0 0.0 0.0 0.0 1027.1 0.0 0.0 46.1 0.0 0.0 1789.2 241.9 0.0 0.0 0.0 233.3 0.0 0.0 0.0 0.0 496.8 132.1 310.6 0.0 0.0 ENAM AIH2 ENSG00000132464 Enamelin Q9NRM1 4 70628744-70646824 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Biomineralization "Amelogenesis imperfecta, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 7.5;heart muscle: 6.5;kidney: 9.0;skeletal muscle: 4.9" "Group enriched" "Detected in some" 4 "Melanocytes: 33.8;Plasma cells: 13.4" "Group enriched" "Detected in some" 5 "pancreatic cancer: 0.6;renal cancer: 1.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "U-266/70: 1.2;U-266/84: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to extracellular matrix" NA NA 23000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 16: U-266 - Nucleosome" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.52e-2)" "unprognostic (2.80e-3)" "unprognostic (1.87e-1)" "unprognostic (1.02e-2)" "unprognostic (2.78e-2)" "unprognostic (1.02e-1)" "unprognostic (7.94e-3)" "unprognostic (4.73e-2)" "unprognostic (2.06e-1)" "unprognostic (9.06e-4)" "unprognostic (1.01e-2)" "unprognostic (1.14e-1)" "prognostic favorable (1.81e-14)" "unprognostic (1.26e-1)" "unprognostic (2.56e-1)" "unprognostic (2.12e-1)" "unprognostic (1.45e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 7.5 0.0 0.3 2.4 6.5 0.0 0.0 9.0 0.5 0.3 0.0 0.0 0.0 0.0 3.6 0.6 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.9 0.0 0.2 0.2 0.0 0.1 1.7 0.6 0.0 0.0 0.0 1.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.6 0.0 0.0 5.1 2.8 0.0 3.7 0.0 0.0 0.0 0.0 3.9 1.0 4.4 0.0 0.0 0.1 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 2.6 0.3 0.1 33.8 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 13.4 0.0 0.0 4.1 0.0 0.2 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.0 1.9 0.0 0.1 0.0 ENHO "C9orf165, UNQ470" ENSG00000168913 "Energy homeostasis associated" Q6UWT2 9 34521043-34522990 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 16 "brain: 475.8;choroid plexus: 256.0" "Cell type enhanced" "Detected in many" "Astrocytes: 71.2;Muller glia cells: 145.1;Oligodendrocyte precursor cells: 28.6" "Cancer enhanced" "Detected in many" "glioma: 44.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 8 "myeloid DC: 28.1" "Lineage enriched" "Detected in many" 8 "dendritic cells: 28.1" "Cell line enhanced" "Detected in many" "AN3-CA: 16.7;NTERA-2: 22.9;SCLC-21H: 11.6;SH-SY5Y: 11.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042575 Approved "Secreted in brain" NA NA 4240000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 5: NTERA-2 - Transcription" "Cluster 5: Muller glia cells - Visual perception" "HPA042575: AB_10794914" "unprognostic (2.63e-2)" "unprognostic (9.53e-3)" "unprognostic (2.46e-1)" "prognostic unfavorable (3.71e-4)" "unprognostic (1.30e-1)" "unprognostic (7.51e-2)" "unprognostic (9.93e-2)" "unprognostic (1.34e-2)" "unprognostic (5.86e-2)" "unprognostic (2.19e-2)" "unprognostic (2.78e-4)" "unprognostic (1.75e-1)" "unprognostic (2.57e-3)" "unprognostic (6.47e-2)" "unprognostic (1.87e-1)" "unprognostic (5.50e-2)" "unprognostic (8.76e-2)" 1.5 0.8 385.2 0.9 422.3 0.8 4.4 360.6 475.8 2.0 256.0 5.9 2.2 0.4 0.2 0.4 2.8 0.7 2.1 344.8 364.6 1.0 23.5 1.5 0.3 400.8 408.7 0.6 1.6 2.3 11.4 0.1 373.1 8.9 2.3 5.7 1.7 0.5 1.0 5.5 4.7 0.2 380.4 0.6 5.5 16.0 459.9 0.2 0.5 0.5 0.2 1.3 1.5 321.5 0.2 1.2 6.5 16.7 0.2 0.0 0.4 0.0 0.0 2.6 2.7 0.7 0.3 2.9 4.5 0.0 5.3 0.2 7.6 0.5 0.6 0.4 7.4 0.0 0.1 1.6 0.2 0.0 3.6 0.0 0.1 0.0 0.3 0.0 0.0 5.4 0.0 2.4 0.6 0.4 0.0 0.0 22.9 1.2 4.7 0.1 0.1 0.4 0.6 0.0 11.6 11.0 0.9 5.2 0.6 0.8 0.3 2.2 0.0 0.5 2.4 0.1 0.1 1.4 1.7 0.1 0.6 0.0 3.9 0.0 0.2 0.0 0.0 3.5 0.0 0.0 0.0 0.0 28.1 0.0 0.0 0.0 0.0 3.6 1.0 1.5 0.0 0.7 385.2 422.3 360.6 475.8 344.8 364.6 400.8 408.7 373.1 380.4 459.9 321.5 0.2 0.0 0.5 71.2 0.3 2.8 2.3 0.0 0.0 4.6 12.0 11.7 0.7 1.5 0.1 0.0 2.1 0.2 0.3 0.0 0.0 0.8 1.0 0.2 7.0 0.7 1.8 1.7 6.4 0.2 0.4 15.5 1.1 0.1 0.0 2.3 1.1 4.8 2.9 5.0 13.6 0.0 0.0 1.0 9.3 5.4 0.3 8.3 1.8 3.7 7.8 145.1 0.0 28.6 7.2 0.0 15.0 0.4 0.0 8.4 0.3 0.5 0.0 4.1 0.0 0.4 0.8 0.7 14.9 0.1 3.1 0.0 0.7 0.1 0.4 0.7 ENPP5 ENSG00000112796 "Ectonucleotide pyrophosphatase/phosphodiesterase family member 5" Q9UJA9 6 46159185-46170980 "Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "epididymis: 243.6" "Cell type enhanced" "Detected in many" "Muller glia cells: 100.1;Respiratory ciliated cells: 47.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 14.9" "Lineage enriched" "Detected in many" 5 "T-cells: 14.9" "Cell line enhanced" "Detected in some" "CAPAN-2: 11.1;HSkMC: 7.1;SuSa: 6.2;T-47d: 8.7;U-266/84: 7.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016902 Enhanced Approved Nucleoplasm,Cytosol "Intracellular and membrane" NA NA 620000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 5: Muller glia cells - Visual perception" Cytosol Nucleoplasm "HPA016902: AB_1848172" "unprognostic (1.12e-1)" "unprognostic (5.19e-2)" "unprognostic (1.98e-1)" "unprognostic (1.32e-1)" "unprognostic (7.61e-2)" "unprognostic (1.63e-1)" "unprognostic (5.01e-2)" "prognostic favorable (4.57e-4)" "unprognostic (1.96e-1)" "unprognostic (9.89e-2)" "prognostic favorable (4.04e-4)" "unprognostic (7.00e-2)" "prognostic favorable (4.44e-13)" "unprognostic (4.40e-2)" "unprognostic (2.78e-2)" "unprognostic (1.61e-1)" "unprognostic (1.60e-1)" 1.8 8.6 6.2 1.1 7.6 0.2 13.4 6.9 12.6 12.8 4.0 2.6 1.5 1.8 243.6 1.8 15.4 7.0 4.4 7.0 9.7 24.3 0.5 8.8 1.2 5.8 13.0 9.7 9.7 46.3 19.8 1.7 6.2 29.4 3.2 30.6 14.4 31.0 10.7 1.6 1.9 0.9 4.5 5.7 6.7 35.5 14.0 8.2 51.0 10.3 1.4 5.6 1.8 6.3 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.5 0.1 0.3 11.1 1.8 3.6 0.2 3.7 0.0 0.6 1.5 0.1 0.0 2.4 0.7 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.4 1.9 0.0 0.5 2.3 5.4 0.0 0.0 0.2 0.2 4.5 0.6 4.7 0.2 0.0 4.6 0.0 6.2 8.7 0.0 0.0 0.0 1.2 0.0 0.1 5.3 7.9 0.0 2.8 0.0 0.1 0.0 0.0 0.0 14.9 0.1 8.0 0.5 3.0 9.7 0.0 0.8 0.9 8.7 1.1 2.8 0.0 0.0 0.0 3.2 6.2 7.6 6.9 12.6 7.0 9.7 5.8 13.0 6.2 4.5 14.0 6.3 0.4 12.8 12.2 16.3 1.6 0.9 4.8 0.5 1.2 10.6 18.1 10.8 7.5 8.6 6.1 23.9 4.2 4.9 4.2 1.9 1.9 11.6 0.7 15.3 0.8 0.4 8.3 0.0 24.6 7.5 2.9 4.2 2.0 5.4 4.5 4.0 0.4 0.1 0.4 10.1 14.5 2.8 2.0 0.0 0.4 3.8 2.8 0.5 0.0 1.9 0.6 100.1 23.7 9.0 10.5 2.2 2.3 12.0 0.1 12.0 1.7 16.3 47.3 3.4 6.6 25.7 1.8 0.5 2.4 1.1 0.6 0.3 3.2 21.2 2.9 3.3 ENPP6 MGC33971 ENSG00000164303 "Ectonucleotide pyrophosphatase/phosphodiesterase 6" Q6UWR7 4 184088706-184221230 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 29.4;kidney: 30.6;ovary: 12.5" "Cell type enhanced" "Detected in some" "Oligodendrocytes: 119.9;Peritubular cells: 35.3;Proximal tubular cells: 31.3;Theca cells: 23.9" "Cancer enriched" "Detected in some" 5 "glioma: 3.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 3.2;SH-SY5Y: 3.6;U-266/70: 2.9;U-266/84: 1.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042740, HPA069197" Enhanced Approved "Golgi apparatus" "Intracellular and membrane" NA NA 290000 "Cluster 21: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Golgi apparatus" "HPA042740: AB_10793984, HPA069197: " "unprognostic (4.81e-4)" "unprognostic (1.47e-1)" "unprognostic (3.54e-2)" "unprognostic (1.24e-1)" "unprognostic (2.56e-1)" "unprognostic (6.69e-3)" "unprognostic (3.07e-2)" "unprognostic (1.27e-2)" "unprognostic (1.03e-1)" "unprognostic (1.09e-1)" "unprognostic (7.60e-3)" "unprognostic (3.04e-2)" "unprognostic (1.72e-1)" "unprognostic (2.98e-2)" "unprognostic (2.82e-1)" "unprognostic (3.93e-3)" "unprognostic (2.01e-1)" 0.2 0.3 2.7 0.8 11.8 0.9 0.8 14.2 5.5 0.2 2.3 1.0 1.7 0.2 6.1 1.0 0.3 0.5 0.2 2.7 6.1 30.6 0.1 0.3 0.9 20.4 9.6 12.5 0.0 0.0 4.2 0.1 18.1 2.2 1.0 0.1 0.7 6.1 0.2 0.1 2.2 0.1 12.5 1.0 1.2 2.4 11.1 1.9 0.1 1.3 2.8 0.6 0.3 29.4 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.9 0.0 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 3.6 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 2.9 1.7 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.0 2.7 11.8 14.2 5.5 2.7 6.1 20.4 9.6 18.1 12.5 11.1 29.4 0.5 0.0 0.0 5.9 0.1 0.0 0.2 0.9 0.6 0.0 0.1 0.5 0.9 0.0 0.4 1.8 0.0 0.0 0.0 0.0 3.9 1.1 1.0 0.0 0.0 0.5 0.0 0.0 4.3 0.2 0.0 8.7 0.0 0.0 5.7 0.0 0.0 0.4 0.2 0.0 1.5 0.0 0.0 0.6 0.0 0.4 4.1 0.6 1.8 4.7 1.1 0.0 0.0 6.6 119.9 0.0 0.0 35.3 0.5 0.1 0.0 31.3 0.2 0.0 0.0 5.1 0.6 0.1 1.6 0.0 0.0 0.0 0.3 23.9 0.0 0.3 EPHA1 "EPH, EPHT, EPHT1" ENSG00000146904 "EPH receptor A1" P21709 7 143390289-143408856 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Angiogenesis, Cell adhesion" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 57.2;parathyroid gland: 206.5" "Cell type enhanced" "Detected in many" "Early spermatids: 23.3;Gastric mucus-secreting cells: 13.3;Proximal enterocytes: 13.2;Squamous epithelial cells: 28.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "memory CD4 T-cell: 1.9;naive CD4 T-cell: 3.8;naive CD8 T-cell: 2.9" "Lineage enriched" "Detected in single" 8 "T-cells: 3.8" "Cell line enhanced" "Detected in some" "CACO-2: 17.9;HaCaT: 16.6;HBEC3-KT: 13.5;MCF7: 15.0;NTERA-2: 54.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" CAB026144 Uncertain NA NA 32000000 "Cluster 32: T-cells - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 5: NTERA-2 - Transcription" "Cluster 61: Squamous epithelial cells - Keratinization" "CAB026144: " "unprognostic (1.54e-2)" "unprognostic (3.04e-2)" "unprognostic (2.07e-1)" "unprognostic (4.58e-3)" "unprognostic (5.82e-3)" "unprognostic (2.45e-2)" "unprognostic (9.56e-2)" "unprognostic (1.81e-2)" "unprognostic (5.09e-1)" "unprognostic (7.59e-3)" "unprognostic (6.54e-2)" "unprognostic (3.24e-3)" "prognostic favorable (1.14e-6)" "unprognostic (3.73e-2)" "unprognostic (3.28e-2)" "unprognostic (1.91e-1)" "unprognostic (1.21e-1)" 0.1 0.0 0.0 1.3 0.0 0.3 2.2 0.4 0.1 11.2 1.2 3.7 8.4 0.3 1.2 57.2 3.4 1.5 0.0 0.0 0.0 5.8 15.6 2.3 2.0 0.0 0.0 0.0 5.7 206.5 2.5 0.6 0.0 4.0 1.6 0.0 11.0 1.2 0.0 19.7 6.2 0.1 0.0 0.9 4.2 1.9 0.0 3.4 5.4 0.0 3.5 1.9 25.8 0.1 8.7 0.0 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 0.0 17.9 7.1 0.0 0.1 0.0 0.0 16.6 0.0 13.5 0.0 0.0 0.0 1.8 0.0 1.7 0.0 0.8 0.1 0.0 4.4 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 15.0 0.0 1.9 54.4 8.8 0.0 0.0 0.0 0.0 1.1 6.7 0.3 0.0 0.0 8.2 0.0 3.2 3.8 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.5 0.2 0.0 3.8 2.9 0.1 0.1 0.0 0.4 0.1 1.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 2.2 0.3 0.1 2.0 6.3 6.5 6.8 0.0 3.3 5.0 1.0 2.8 9.9 7.3 0.0 2.0 0.2 4.2 0.0 4.4 23.3 4.0 1.0 0.2 1.2 0.0 0.6 4.3 2.6 0.5 13.3 6.6 0.0 0.0 0.4 8.8 0.4 0.0 0.3 4.7 2.0 0.3 0.3 9.9 0.6 0.3 0.0 1.0 0.0 0.3 0.0 0.5 0.2 6.3 8.8 0.0 0.6 2.0 13.2 1.5 2.1 0.2 0.0 0.4 0.4 0.5 1.9 28.7 3.7 1.0 4.4 0.0 7.6 5.5 EPHA3 "ETK, ETK1, HEK, HEK4, TYRO4" ENSG00000044524 "EPH receptor A3" P29320 3 89107621-89482134 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 31.5" "Group enriched" "Detected in some" 4 "Excitatory neurons: 70.6;Inhibitory neurons: 106.6;Microglial cells: 103.0;Oligodendrocytes: 48.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "AF22: 197.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB010462, HPA069390" Approved Supported "Nucleoplasm,Nuclear membrane,Plasma membrane,Actin filaments,Cytosol" "Intracellular and membrane" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear membrane, Plasma membrane, Cytosol" "Nucleoplasm, Actin filaments" "CAB010462: AB_2099218, HPA069390: " "unprognostic (1.48e-3)" "unprognostic (2.30e-2)" "unprognostic (4.95e-2)" "unprognostic (1.90e-1)" "unprognostic (2.96e-2)" "unprognostic (1.47e-2)" "unprognostic (2.03e-1)" "unprognostic (9.10e-3)" "unprognostic (1.24e-3)" "unprognostic (7.43e-2)" "unprognostic (1.83e-1)" "unprognostic (2.23e-1)" "prognostic unfavorable (3.28e-7)" "unprognostic (3.63e-2)" "unprognostic (1.88e-2)" "unprognostic (4.05e-2)" "unprognostic (1.20e-2)" 5.4 1.0 2.1 1.8 1.3 0.0 2.3 0.2 3.8 12.3 0.1 3.8 2.3 5.5 0.2 3.2 1.3 18.8 8.2 2.2 0.7 1.3 4.9 2.4 3.6 3.3 0.9 4.1 2.1 1.0 0.9 20.1 4.0 31.5 6.2 8.0 2.2 7.1 0.8 0.7 2.4 7.9 0.8 0.9 2.5 1.0 1.7 1.0 11.0 6.3 3.2 14.3 6.4 2.2 0.0 0.0 197.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 0.0 11.2 0.2 0.7 0.0 2.4 0.0 0.0 11.8 0.0 0.0 1.7 2.0 0.0 3.9 0.0 0.0 0.6 0.0 2.5 0.1 0.3 0.0 2.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.1 0.0 0.1 0.0 0.5 0.1 0.1 36.1 0.1 0.0 0.0 1.7 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 1.3 0.2 3.8 2.2 0.7 3.3 0.9 4.0 0.8 1.7 2.2 2.2 0.0 0.0 5.5 0.0 0.5 0.3 0.0 0.6 6.4 0.0 0.1 2.4 0.0 0.0 0.0 2.1 0.2 0.0 0.0 0.0 0.0 1.8 0.0 0.5 1.8 0.0 0.0 70.6 0.0 0.1 18.1 0.5 0.0 0.0 0.0 1.1 0.0 0.1 20.2 106.6 0.0 0.0 0.0 0.7 1.6 2.1 0.1 0.0 103.0 0.0 4.7 0.0 2.5 48.0 0.0 0.0 8.2 0.0 0.1 0.0 0.0 0.0 18.7 6.6 0.7 19.2 0.1 0.0 0.3 0.3 0.5 0.2 1.3 0.0 0.1 EPHA4 "Hek8, TYRO1" ENSG00000116106 "EPH receptor A4" P54764 2 221418027-221574202 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 39.7" "Cell type enriched" "Detected in many" 4 "Excitatory neurons: 317.9" "Cancer enhanced" "Detected in many" "thyroid cancer: 14.9" "Group enriched" "Detected in many" 6 "cerebral cortex: 23.8;hippocampal formation: 20.9" "Group enriched" "Detected in many" 9 "basophil: 1.6;gdT-cell: 1.7;MAIT T-cell: 1.7;memory B-cell: 1.3;memory CD4 T-cell: 2.5;memory CD8 T-cell: 1.7;naive B-cell: 1.2;naive CD4 T-cell: 1.0;NK-cell: 3.5;T-reg: 1.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 77.0;ASC diff: 33.9;CACO-2: 59.3;U-2197: 38.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB028368 Enhanced NA NA 9300000 "Cluster 22: NK-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "CAB028368: AB_2099353" "unprognostic (1.28e-1)" "unprognostic (5.87e-2)" "unprognostic (2.28e-1)" "unprognostic (2.46e-2)" "unprognostic (5.99e-2)" "unprognostic (1.33e-1)" "unprognostic (7.05e-4)" "unprognostic (1.80e-2)" "unprognostic (2.40e-1)" "prognostic unfavorable (9.56e-4)" "unprognostic (1.12e-1)" "unprognostic (2.85e-2)" "prognostic favorable (5.67e-4)" "unprognostic (3.12e-2)" "unprognostic (1.96e-1)" "unprognostic (2.36e-1)" "unprognostic (8.66e-2)" 7.8 1.6 0.0 1.9 3.9 3.7 3.9 0.0 23.8 4.5 39.7 4.6 1.0 6.4 2.8 4.8 4.9 3.1 17.4 20.9 0.0 4.8 0.8 3.6 2.7 0.0 1.5 11.1 1.1 1.9 0.6 1.6 0.0 5.3 4.5 4.2 2.6 6.1 2.7 12.9 2.8 8.0 0.0 3.4 2.3 11.7 3.7 3.8 9.5 4.0 3.2 3.6 3.5 0.0 2.6 2.4 77.0 0.0 33.9 20.9 0.1 18.2 8.3 16.9 6.2 59.3 0.9 0.0 0.1 26.7 0.0 7.0 12.3 0.1 7.0 9.7 6.4 0.0 0.9 0.0 0.9 0.0 1.4 8.5 4.2 5.3 0.1 10.3 14.9 0.0 0.0 0.0 4.4 9.5 0.2 0.0 5.6 5.9 1.7 0.1 8.5 0.0 25.8 4.3 13.2 0.0 6.2 1.3 1.3 6.2 2.9 0.0 0.0 1.7 3.2 38.4 1.0 0.0 0.1 0.0 6.9 0.0 3.6 1.6 0.0 0.0 1.7 0.0 1.7 1.3 2.5 1.7 0.0 1.2 1.0 0.2 0.1 3.5 0.0 0.1 1.2 0.4 0.0 3.9 0.0 23.8 20.9 0.0 0.0 1.5 0.0 0.0 3.7 0.0 36.3 0.0 6.4 51.9 8.2 6.1 0.7 9.7 2.8 9.8 4.3 6.0 31.6 7.2 13.7 9.2 0.0 0.1 12.2 4.7 7.9 0.2 3.9 1.9 5.7 26.3 3.5 0.0 317.9 0.2 0.0 5.1 4.6 5.2 1.3 9.0 20.0 0.4 0.3 1.7 68.8 12.8 8.2 0.0 1.5 5.8 1.2 0.9 7.2 70.3 0.2 7.2 3.1 8.0 7.9 30.9 3.6 8.6 2.1 1.4 0.1 1.7 4.5 3.2 0.0 3.6 10.2 10.0 1.9 4.1 12.5 0.0 5.4 11.3 6.6 2.4 EPM2A "LD, LDE" ENSG00000112425 "EPM2A glucan phosphatase, laforin" O95278 6 145382535-145736023 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Autophagy, Carbohydrate metabolism, Glycogen metabolism" "Hydrolase, Protein phosphatase" "Disease variant, Epilepsy, Glycogen storage disease, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 76.8;tongue: 79.5" "Cell type enhanced" "Detected in many" "Astrocytes: 66.9;Early spermatids: 33.0;Excitatory neurons: 30.4;Inhibitory neurons: 50.7;Oligodendrocyte precursor cells: 56.8;Oligodendrocytes: 60.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 1.9" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Daudi: 23.2" "Low region specificity" "Detected in all" "HPA053643, HPA055468" Enhanced Nucleoplasm NA NA "Cluster 15: NK-cells - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA053643: AB_2797247, HPA055468: AB_2797252" "unprognostic (2.37e-2)" "unprognostic (1.03e-1)" "unprognostic (1.99e-1)" "unprognostic (3.34e-3)" "unprognostic (2.92e-3)" "unprognostic (1.22e-1)" "unprognostic (2.15e-2)" "unprognostic (1.63e-1)" "unprognostic (2.37e-2)" "unprognostic (1.50e-1)" "unprognostic (1.52e-4)" "unprognostic (2.28e-1)" "prognostic favorable (4.08e-7)" "unprognostic (4.12e-4)" "unprognostic (2.17e-1)" "unprognostic (2.99e-3)" "unprognostic (1.23e-1)" 5.8 6.0 11.4 1.5 11.7 1.8 3.2 11.9 17.8 3.1 7.3 17.2 3.2 6.0 4.3 9.3 4.4 3.6 24.4 11.6 12.6 8.5 5.7 3.0 3.3 11.9 11.5 5.7 2.4 5.2 3.8 1.5 11.1 6.1 2.9 12.1 3.1 8.8 76.8 2.1 3.8 6.3 10.3 2.1 5.3 3.0 11.5 4.8 3.9 79.5 2.6 9.8 2.7 13.3 1.3 2.1 3.4 6.6 8.6 2.3 1.6 3.1 3.8 2.9 3.5 1.7 1.7 23.2 2.7 3.8 3.5 1.8 1.3 1.6 2.6 9.3 1.9 3.6 2.5 2.7 4.8 12.7 2.4 2.0 7.0 1.7 0.7 3.8 2.0 5.0 1.8 5.4 3.8 3.1 8.4 3.2 3.9 3.2 1.9 4.8 3.1 6.7 2.5 1.8 6.3 6.4 5.5 3.3 7.8 3.1 1.9 7.3 4.6 2.9 1.1 2.7 2.6 4.1 4.6 8.6 2.6 2.8 4.8 0.0 0.0 0.0 0.1 0.5 0.4 0.4 0.4 0.3 0.3 0.4 0.4 0.9 0.1 1.9 0.1 0.3 0.0 0.3 11.4 11.7 11.9 17.8 11.6 12.6 11.9 11.5 11.1 10.3 11.5 13.3 3.9 6.4 1.5 66.9 4.4 0.9 1.0 0.8 0.6 8.4 3.5 2.2 27.8 2.8 2.2 1.8 6.2 1.0 1.9 0.2 11.7 1.0 33.0 1.9 3.6 2.2 1.2 4.4 30.4 2.3 0.7 2.3 1.1 1.4 2.5 6.0 1.4 6.6 2.3 30.3 50.7 1.5 2.0 3.3 1.4 19.8 3.1 3.1 7.2 15.9 1.7 7.9 2.1 56.8 60.1 1.2 1.7 2.2 1.7 1.5 0.5 7.1 2.2 6.3 0.0 6.2 2.4 4.9 1.6 0.8 0.4 0.4 1.8 5.1 1.2 0.3 EPPIN "CT71, dJ461P17.2, EPPIN1, EPPIN2, EPPIN3, SPINLW1, WAP7, WFDC7" ENSG00000101448 "Epididymal peptidase inhibitor" O95925 20 45540626-45547752 "Predicted intracellular proteins, Predicted secreted proteins" "Antimicrobial, Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 83 "epididymis: 327.9;testis: 84.2" "Group enriched" "Detected in some" 4 "Endometrial ciliated cells: 30.0;Granulosa cells: 13.6;Late spermatids: 29.2;Respiratory ciliated cells: 32.5;Sertoli cells: 13.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 1.8;U-87 MG: 2.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA067335 Supported "Secreted in male reproductive system" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 49: Ciliated cells - Cilium organization" "HPA067335: " "unprognostic (1.17e-1)" "unprognostic (1.79e-1)" "unprognostic (3.08e-3)" "unprognostic (1.06e-2)" "unprognostic (3.75e-2)" "unprognostic (1.69e-1)" "unprognostic (2.94e-2)" "unprognostic (2.00e-2)" 0.3 0.3 0.7 0.3 1.1 2.4 0.2 1.9 2.4 0.5 0.1 0.4 0.7 0.7 327.9 0.3 1.3 0.2 0.1 0.9 0.0 0.2 2.3 0.4 0.5 0.1 0.0 0.2 0.1 0.0 0.0 0.2 0.6 0.2 0.4 1.2 0.3 0.8 0.2 0.8 0.7 0.1 0.0 0.4 0.2 84.2 0.4 0.0 0.7 0.0 0.2 0.1 0.0 2.0 0.8 0.1 0.3 0.3 0.0 0.1 0.5 0.8 0.0 0.0 0.0 0.5 0.3 0.6 0.3 0.0 0.6 0.3 0.1 0.0 0.0 0.5 0.1 0.3 0.5 0.4 0.0 0.2 0.8 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.6 1.8 0.0 0.4 0.2 0.7 0.8 0.1 0.2 0.7 0.2 0.5 0.1 0.2 0.3 0.5 0.3 0.1 0.3 0.3 0.4 0.4 0.7 0.7 0.6 0.9 0.5 0.6 0.8 0.3 2.6 0.2 0.8 0.8 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.7 1.1 1.9 2.4 0.9 0.0 0.1 0.0 0.6 0.0 0.4 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.1 0.1 0.4 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 30.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 13.6 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 29.2 4.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 32.5 0.0 13.1 0.0 0.4 5.6 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 ERBIN "ERBB2IP, LAP2" ENSG00000112851 "Erbb2 interacting protein" Q96RT1 5 65926556-66082546 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 119.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 70.5;dendritic cells: 61.3;Endometrial ciliated cells: 62.3;Glandular and luminal cells: 101.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048606, HPA059863" Approved Supported "Nuclear speckles,Plasma membrane" NA NA 39000 "Cluster 38: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 7: Non-specific - Mitochondria" "Nuclear speckles, Plasma membrane" "HPA048606: AB_2680461, HPA059863: AB_2684146" "unprognostic (4.34e-1)" "unprognostic (5.56e-2)" "unprognostic (9.88e-2)" "unprognostic (2.15e-2)" "unprognostic (2.04e-1)" "unprognostic (4.23e-3)" "unprognostic (1.74e-1)" "unprognostic (1.01e-1)" "unprognostic (1.46e-2)" "unprognostic (6.52e-2)" "unprognostic (5.45e-3)" "unprognostic (7.98e-2)" "unprognostic (5.62e-3)" "unprognostic (7.21e-3)" "unprognostic (3.08e-1)" "unprognostic (6.86e-2)" "unprognostic (7.81e-2)" 15.7 14.5 65.2 29.5 109.6 30.0 24.7 64.2 67.6 23.2 19.0 27.8 24.5 22.6 27.0 20.1 20.0 28.4 16.9 56.2 91.6 29.5 33.3 21.5 40.6 91.3 88.0 20.0 18.8 22.6 8.3 16.4 106.0 26.4 26.3 28.1 21.8 20.2 19.8 32.8 44.1 19.7 64.4 31.4 40.3 27.5 86.6 48.7 29.9 20.7 39.0 28.5 13.0 119.1 97.8 32.2 41.5 49.6 30.0 36.0 31.5 61.5 62.6 85.3 94.3 31.5 113.8 82.2 58.8 95.3 67.2 31.7 26.5 45.1 149.4 36.3 12.0 28.3 41.3 24.7 39.5 22.0 26.3 39.4 29.2 47.2 67.5 50.0 32.1 37.1 29.4 54.6 58.1 33.5 59.0 25.1 10.1 9.7 9.5 53.7 33.0 45.8 49.9 65.6 20.0 18.7 65.0 21.7 46.4 30.9 38.4 53.8 29.8 48.3 85.9 29.8 80.8 47.2 31.7 69.8 31.6 35.9 28.1 13.1 4.1 5.5 5.2 5.8 4.8 4.7 3.9 4.6 3.5 3.7 4.5 4.8 9.2 3.9 5.1 2.2 3.8 2.8 65.2 109.6 64.2 67.6 56.2 91.6 91.3 88.0 106.0 64.4 86.6 119.1 53.0 70.5 57.5 0.0 13.2 0.0 0.0 0.0 0.0 0.0 39.4 24.8 0.0 0.0 31.6 53.3 0.0 6.5 61.3 0.0 11.7 26.7 0.0 62.3 50.0 26.1 0.0 0.0 0.0 24.9 11.2 16.2 0.0 101.9 27.8 47.8 0.0 0.0 40.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.4 0.0 0.0 5.7 0.0 0.0 0.0 0.0 50.3 0.0 0.0 13.3 0.0 0.0 41.7 24.0 0.0 0.0 0.0 17.1 0.0 0.0 0.0 0.0 8.9 20.0 51.4 0.0 0.0 ERF "PE-2, PE2" ENSG00000105722 "ETS2 repressor factor" P50548 19 42247569-42255128 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 157.0;Suprabasal keratinocytes: 109.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058532, HPA067952" Approved Enhanced Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 35: Glandular cells - Unknown function" Nucleoplasm "HPA058532: AB_2683744, HPA067952: AB_2685932" "prognostic favorable (8.07e-4)" "unprognostic (2.86e-1)" "unprognostic (1.47e-2)" "unprognostic (9.07e-2)" "unprognostic (5.21e-2)" "unprognostic (6.66e-2)" "unprognostic (2.21e-1)" "unprognostic (7.27e-3)" "unprognostic (3.61e-2)" "unprognostic (2.20e-1)" "unprognostic (8.63e-3)" "unprognostic (3.24e-1)" "unprognostic (6.41e-2)" "unprognostic (1.63e-1)" "unprognostic (2.85e-1)" "unprognostic (1.91e-2)" "unprognostic (1.54e-2)" 38.2 31.8 21.1 21.9 23.7 15.2 35.1 16.5 24.3 35.8 10.4 37.1 34.4 48.2 17.4 25.6 49.9 50.1 37.8 19.5 23.9 37.5 43.4 41.6 20.0 22.3 22.5 43.0 29.1 21.0 40.3 18.5 19.5 30.9 10.0 14.6 26.4 17.2 11.6 33.5 34.4 19.9 17.5 31.4 29.8 32.8 21.9 24.2 38.7 18.0 15.6 29.7 31.3 37.7 57.6 136.4 57.7 65.8 12.7 32.4 16.4 53.3 37.4 53.5 54.0 63.2 65.1 47.4 32.9 49.3 48.0 61.7 42.1 124.4 39.2 23.5 29.1 28.5 82.9 80.1 34.3 33.2 45.5 37.1 41.3 41.4 45.5 69.6 45.0 37.9 62.0 38.4 29.8 115.8 38.0 25.0 48.5 54.4 29.3 46.6 21.0 20.1 33.5 49.1 26.6 54.2 59.4 43.4 61.8 39.1 43.6 58.7 54.2 78.4 112.9 27.4 100.0 43.2 53.1 39.0 76.9 35.3 108.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 21.1 23.7 16.5 24.3 19.5 23.9 22.3 22.5 19.5 17.5 21.9 37.7 63.3 3.2 1.7 7.8 25.0 157.0 30.2 19.8 77.4 14.1 95.0 57.9 7.3 25.8 6.3 9.2 22.9 7.2 21.7 21.6 7.9 19.1 9.4 35.1 20.5 43.7 26.4 7.8 4.2 15.8 4.9 27.2 13.7 23.4 11.4 10.0 41.4 30.2 11.7 10.1 1.5 22.9 2.0 14.5 58.6 4.1 11.1 22.9 55.2 7.5 7.3 19.0 3.1 3.5 8.5 15.3 27.2 10.1 11.2 18.8 34.6 23.3 11.9 12.3 13.1 61.0 39.8 3.0 16.2 37.9 109.7 14.8 25.5 10.2 21.7 17.6 ERG "erg-3, p55" ENSG00000157554 "ETS transcription factor ERG" P11308 21 38380027-38661780 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 94.4;Endothelial cells: 105.5;Hepatic stellate cells: 69.9;Microglial cells: 88.1" "Cancer enriched" "Detected in all" 4 "prostate cancer: 18.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HUVEC TERT2: 138.3;MOLT-4: 47.7;REH: 151.5;TIME: 113.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018377, HPA046598" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Cytosol "CAB018377: AB_675518, HPA046598: AB_2679715" "unprognostic (2.14e-1)" "prognostic unfavorable (6.18e-6)" "unprognostic (6.44e-3)" "unprognostic (8.64e-3)" "unprognostic (5.65e-2)" "unprognostic (1.91e-1)" "unprognostic (9.03e-4)" "unprognostic (4.30e-2)" "unprognostic (2.63e-2)" "unprognostic (1.29e-1)" "unprognostic (3.42e-2)" "unprognostic (2.89e-1)" "prognostic unfavorable (3.94e-4)" "unprognostic (4.31e-3)" "unprognostic (3.88e-2)" "unprognostic (2.64e-2)" "unprognostic (5.63e-3)" 24.6 4.1 5.1 7.1 5.5 7.6 20.0 5.0 5.5 10.0 3.0 5.4 3.4 11.6 1.9 5.2 9.1 12.0 12.4 4.5 5.1 12.8 6.1 19.6 7.5 5.9 5.4 4.4 4.9 2.4 2.4 24.3 6.2 7.1 3.4 0.5 3.7 4.3 7.9 4.9 6.5 12.0 4.7 26.6 4.6 1.5 7.0 4.1 10.0 9.9 3.7 9.2 6.9 5.4 0.0 0.0 1.5 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.6 0.0 0.0 0.2 22.3 0.0 0.1 0.9 0.0 0.0 138.3 0.1 0.0 0.0 0.0 1.0 47.7 0.0 0.5 0.0 0.0 151.5 0.0 0.0 0.0 0.1 0.1 0.0 1.1 0.2 0.0 0.0 0.0 0.0 113.4 0.7 2.2 0.5 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.1 5.5 5.0 5.5 4.5 5.1 5.9 5.4 6.2 4.7 7.0 5.4 94.4 0.0 3.9 0.3 0.7 3.4 1.7 0.6 3.4 0.0 0.6 4.3 3.8 4.3 1.3 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.7 0.7 0.4 105.5 0.0 13.5 13.3 0.0 0.0 5.7 0.0 2.1 24.0 4.4 69.9 1.3 0.3 0.0 1.7 0.4 0.0 5.9 3.4 2.1 0.9 0.9 3.6 88.1 0.2 0.0 0.0 7.1 1.4 0.0 0.0 0.0 1.5 1.4 0.0 0.0 0.0 0.1 0.0 2.4 3.7 0.3 1.4 0.5 3.4 0.0 0.6 0.5 0.3 0.6 ERGIC2 "Erv41, PTX1" ENSG00000087502 "ERGIC and golgi 2" Q96RQ1 12 29337352-29381189 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "ER-Golgi transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 383.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049695 Approved Supported "Nucleoli rim,Golgi apparatus,Vesicles" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 18: U-2197 - ECM organization" "Cluster 29: Early spermatids - Spermatogenesis" "Golgi apparatus, Vesicles" "Nucleoli rim" "HPA049695: AB_2680855" "unprognostic (1.62e-2)" "unprognostic (3.50e-2)" "unprognostic (5.53e-2)" "unprognostic (3.56e-1)" "unprognostic (1.45e-1)" "unprognostic (5.19e-3)" "prognostic unfavorable (8.06e-6)" "unprognostic (3.70e-2)" "unprognostic (2.32e-2)" "prognostic favorable (8.18e-4)" "prognostic unfavorable (7.02e-6)" "unprognostic (2.67e-1)" "prognostic unfavorable (3.76e-6)" "unprognostic (6.02e-2)" "unprognostic (2.08e-1)" "unprognostic (3.19e-2)" "unprognostic (2.64e-1)" 38.5 32.5 22.7 37.8 24.6 10.5 46.0 25.1 29.0 34.4 20.8 37.1 34.4 34.4 50.1 46.0 24.2 33.1 52.4 22.6 25.9 30.6 47.6 26.3 33.8 24.9 23.9 26.9 40.2 47.2 20.7 53.1 24.3 39.5 33.7 29.4 49.2 34.5 33.8 19.2 34.9 39.3 25.4 26.7 32.6 57.8 24.4 35.0 45.1 47.0 43.6 50.1 22.1 34.4 96.7 87.0 69.1 46.8 94.8 111.5 170.1 153.1 123.4 92.7 98.3 115.7 157.6 51.3 149.1 120.7 168.7 98.7 66.0 98.3 146.4 112.6 69.4 84.0 114.6 68.3 55.7 121.2 70.0 79.1 75.9 115.8 116.7 169.3 71.8 69.8 70.5 144.6 122.6 52.3 60.3 126.2 98.9 101.3 235.0 54.9 189.9 107.6 75.5 140.1 26.5 43.2 77.2 86.5 91.5 145.9 168.0 96.7 81.8 124.1 108.1 169.1 167.6 106.4 145.5 106.0 103.7 87.3 105.3 92.3 50.2 70.6 84.7 79.9 102.9 83.2 107.6 101.2 55.1 71.0 106.6 90.3 181.1 72.1 101.1 120.9 130.8 90.1 22.7 24.6 25.1 29.0 22.6 25.9 24.9 23.9 24.3 25.4 24.4 34.4 54.6 28.9 28.6 20.9 74.3 57.9 68.9 144.1 39.9 54.8 57.2 55.1 61.7 38.6 99.0 53.3 54.2 119.2 60.8 19.4 49.0 72.7 383.0 48.7 66.5 43.7 41.8 44.8 39.2 62.8 120.6 73.0 25.5 54.6 55.8 44.2 34.6 50.2 56.4 48.8 37.8 33.5 87.5 25.5 40.2 51.9 52.5 37.1 62.2 14.0 41.6 69.5 52.5 32.2 48.3 58.1 20.5 59.8 154.0 85.7 32.4 49.5 64.6 60.0 32.9 58.5 105.7 75.0 36.3 49.4 66.3 156.2 68.0 54.0 34.7 78.8 ERI2 "EXOD1, KIAA1504, MGC16943, ZGRF5" ENSG00000196678 "ERI1 exoribonuclease family member 2" A8K979 16 20780193-20900349 "Predicted intracellular proteins" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 39.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 13.8" "Lineage enriched" "Detected in many" 5 "granulocytes: 13.8" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035384, HPA035385" Uncertain Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 1: K-562 - Erythropoiesis" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Golgi apparatus" "HPA035384: AB_10602316, HPA035385: AB_2674600" "unprognostic (1.25e-1)" "unprognostic (1.47e-1)" "unprognostic (2.01e-3)" "unprognostic (4.36e-2)" "unprognostic (8.64e-2)" "unprognostic (2.78e-1)" "unprognostic (1.49e-1)" "unprognostic (1.55e-1)" "unprognostic (5.99e-2)" "unprognostic (3.04e-2)" "unprognostic (2.07e-2)" "unprognostic (1.08e-1)" "unprognostic (2.56e-2)" "unprognostic (1.54e-1)" "unprognostic (2.45e-1)" "unprognostic (1.05e-2)" "unprognostic (9.28e-3)" 4.7 6.8 4.3 3.7 4.9 6.4 9.2 4.4 5.5 3.9 4.8 7.4 8.1 4.1 7.6 6.7 5.7 4.5 4.4 4.1 4.4 6.5 12.1 4.7 3.8 4.9 4.4 4.5 7.4 14.0 5.0 5.4 4.9 7.5 10.2 4.2 5.1 4.8 5.1 7.1 7.8 4.6 4.6 3.6 8.4 13.1 4.7 7.5 6.2 3.7 4.4 4.5 4.7 5.7 17.1 7.9 21.6 9.5 6.5 8.3 13.0 13.3 7.9 11.8 14.9 10.2 17.0 4.8 14.6 7.3 8.2 12.7 21.8 13.7 21.8 15.3 11.4 11.5 9.7 17.6 6.0 22.3 9.0 7.5 16.7 15.9 13.2 6.3 7.2 0.0 37.1 13.5 20.0 15.3 3.2 19.8 13.4 17.5 4.5 25.5 17.7 10.5 11.0 13.4 11.0 13.5 8.5 16.0 10.3 11.4 33.7 24.7 5.5 12.5 7.0 12.2 17.9 8.3 13.4 2.9 11.9 17.9 17.6 13.8 1.8 1.7 0.4 1.3 0.3 0.5 0.4 0.4 1.9 0.0 0.3 0.2 0.1 0.5 2.6 0.6 0.8 0.4 4.3 4.9 4.4 5.5 4.1 4.4 4.9 4.4 4.9 4.6 4.7 5.7 4.0 16.0 6.7 18.3 1.0 5.0 5.3 5.6 8.0 5.3 11.3 5.8 7.3 5.7 8.5 9.2 0.0 8.3 0.9 8.0 9.8 4.1 22.5 6.9 5.5 3.0 0.0 22.7 10.4 5.2 9.1 4.3 9.7 6.0 0.0 7.1 2.9 10.9 8.4 3.3 10.6 9.6 6.1 8.2 4.1 14.7 6.2 5.8 1.8 5.6 6.7 5.0 3.1 10.6 20.3 4.7 6.6 5.3 2.8 4.5 7.5 6.8 12.6 3.5 0.0 5.6 3.5 39.3 20.0 9.7 3.7 3.7 2.5 4.5 8.5 5.7 ERMARD "C6orf70, dJ266L20.3, FLJ11152" ENSG00000130023 "ER membrane associated RNA degradation" Q5T6L9 6 169751622-169781600 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 49.9;Late spermatids: 48.5;Spermatocytes: 37.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041741 Approved Approved Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 71: Testis - DNA repair" "Cluster 30: Epithelial cell lines - Translation" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "HPA041741: AB_10804116" "unprognostic (2.66e-3)" "unprognostic (2.75e-1)" "unprognostic (2.33e-1)" "unprognostic (2.28e-2)" "unprognostic (1.18e-1)" "unprognostic (3.18e-1)" "unprognostic (2.24e-2)" "unprognostic (7.41e-3)" "unprognostic (1.96e-1)" "unprognostic (8.14e-2)" "unprognostic (1.66e-3)" "unprognostic (4.74e-2)" "unprognostic (3.06e-2)" "unprognostic (3.08e-1)" "unprognostic (1.88e-1)" "unprognostic (2.71e-1)" "unprognostic (1.31e-2)" 13.8 14.6 5.3 8.4 7.1 10.1 13.1 5.4 6.7 13.7 5.6 11.2 6.3 13.8 20.5 10.5 13.2 7.7 6.8 5.3 5.9 16.1 18.6 9.7 13.8 6.9 6.1 17.4 11.4 6.9 15.4 7.4 7.2 12.7 7.4 14.6 11.0 8.6 14.9 18.7 13.6 6.4 6.5 17.3 10.9 22.1 6.1 9.9 13.2 2.5 13.6 11.2 10.8 9.1 5.1 7.5 9.7 14.8 6.9 11.4 5.1 5.3 7.7 5.0 6.3 2.0 8.3 8.0 4.8 6.5 6.1 13.3 4.0 10.3 4.4 8.6 4.4 11.5 9.9 3.0 13.7 16.1 7.6 13.4 10.4 6.1 15.5 12.8 3.4 14.0 8.0 11.4 6.5 7.7 6.8 14.4 3.2 5.7 5.4 7.5 6.0 13.0 6.2 4.0 3.8 7.0 9.0 9.0 4.9 6.3 7.1 12.8 5.3 5.7 3.4 9.1 6.5 13.1 17.5 6.7 7.2 9.7 6.6 1.6 4.2 1.8 5.2 7.9 5.2 5.1 6.0 5.9 4.4 6.0 4.7 4.4 0.4 5.2 9.7 3.7 7.6 3.9 5.3 7.1 5.4 6.7 5.3 5.9 6.9 6.1 7.2 6.5 6.1 9.1 8.5 3.2 11.1 20.2 6.2 4.1 4.4 7.7 5.2 12.0 5.9 5.1 2.8 5.7 7.7 5.5 10.4 12.2 4.7 3.0 11.7 9.8 49.9 10.8 9.4 5.0 6.0 4.6 9.3 8.5 8.3 7.0 5.6 6.9 2.5 11.7 7.9 10.1 5.9 5.0 11.8 2.9 6.1 5.7 4.4 48.5 4.4 6.1 3.6 8.4 5.6 14.6 5.2 17.1 20.7 5.3 2.4 4.5 4.4 2.5 5.7 9.5 15.5 10.8 6.6 5.5 5.8 37.8 18.0 5.5 3.1 7.1 4.7 10.3 3.4 3.4 ERV3-1 "envR, ERV-R, ERV3, H-PLK, HERV-R" ENSG00000213462 "Endogenous retrovirus group 3 member 1, envelope" Q14264 7 64990356-65006743 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 7.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AN3-CA: 27.7" "HPA017209, HPA046508" Enhanced Approved Vesicles NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 68: Epididymis - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 52: Non-specific - Transcription" Vesicles "HPA017209: AB_2732419, HPA046508: AB_2732525" "unprognostic (2.74e-2)" "unprognostic (1.84e-1)" "unprognostic (2.11e-1)" "unprognostic (1.27e-2)" "unprognostic (4.48e-1)" "unprognostic (2.03e-1)" "unprognostic (7.00e-2)" "unprognostic (1.79e-1)" "unprognostic (4.05e-3)" "unprognostic (3.55e-1)" "unprognostic (1.57e-2)" "unprognostic (4.45e-2)" "unprognostic (4.27e-3)" "unprognostic (2.11e-1)" "unprognostic (2.19e-1)" "unprognostic (9.39e-2)" "unprognostic (1.88e-2)" 22.8 33.0 4.8 8.5 4.5 9.3 15.0 4.1 6.4 10.0 5.1 5.7 3.5 10.0 32.5 15.2 8.0 16.4 6.2 4.7 6.2 4.8 3.2 9.7 5.7 6.2 7.9 7.3 5.3 15.3 8.2 13.4 5.4 7.3 5.7 13.5 12.1 7.5 3.6 12.3 4.5 7.6 4.8 6.9 6.3 8.7 5.9 6.6 7.6 1.8 7.4 6.2 11.5 5.1 3.3 1.0 17.4 27.7 11.3 4.7 12.4 5.7 6.3 2.0 4.6 1.2 20.5 5.5 5.3 2.2 4.0 3.9 2.6 1.5 3.2 4.1 1.5 2.8 1.6 11.5 1.0 6.7 3.7 5.1 1.6 1.8 0.6 10.4 11.6 6.0 12.7 10.3 8.1 8.1 4.9 5.0 5.1 10.8 1.2 11.4 0.7 3.7 3.5 6.8 3.6 16.8 6.2 1.9 0.7 18.9 4.7 16.4 9.2 6.7 1.0 5.1 2.8 3.2 7.8 1.6 5.7 20.8 4.1 0.0 1.0 2.4 0.6 1.8 0.5 0.4 0.1 0.4 0.8 0.5 0.3 0.4 7.0 1.1 0.5 0.4 1.2 0.6 4.8 4.5 4.1 6.4 4.7 6.2 6.2 7.9 5.4 4.8 5.9 5.1 7.1 3.2 13.1 17.9 32.5 4.2 15.6 17.0 7.4 24.8 13.7 10.4 2.1 24.3 25.5 16.5 29.2 16.5 21.6 4.4 9.8 14.4 7.3 6.2 8.6 10.9 13.8 19.4 12.2 17.9 12.7 8.3 12.8 5.9 8.2 20.4 13.6 3.6 9.7 18.5 13.0 9.1 16.2 21.8 16.5 4.8 11.5 19.8 10.6 14.0 16.7 11.3 36.0 24.1 14.0 17.6 7.8 9.8 10.0 12.5 15.4 4.9 14.0 21.4 6.6 7.6 8.7 12.2 11.8 8.6 5.7 40.2 20.5 10.7 6.7 31.1 ESRRB "DFNB35, ERR2, ERRb, ERRbeta, ESRL2, NR3B2" ENSG00000119715 "Estrogen related receptor beta" O95718 14 76310712-76501837 "Disease related genes, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "retina: 36.5" "Cell type enhanced" "Detected in some" "Distal tubular cells: 13.7;Early spermatids: 14.1;Horizontal cells: 55.5;Late spermatids: 37.6;Rod photoreceptor cells: 40.3" "Cancer enhanced" "Detected in single" "testis cancer: 0.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 1.3;K-562: 5.0;U-266/70: 2.3" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA074772 Supported Nucleoplasm,Cytosol NA NA "Cluster 77: Retina - Visual perception" "Cluster 1: K-562 - Erythropoiesis" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm Cytosol "HPA074772: " "unprognostic (1.12e-1)" "unprognostic (1.34e-2)" "unprognostic (6.28e-2)" "unprognostic (3.92e-5)" "unprognostic (5.18e-2)" "unprognostic (3.15e-2)" "unprognostic (2.14e-1)" "unprognostic (1.48e-1)" "unprognostic (2.28e-2)" "unprognostic (2.24e-2)" "unprognostic (2.16e-2)" "unprognostic (4.11e-2)" "unprognostic (2.68e-1)" "unprognostic (3.46e-1)" "unprognostic (1.89e-1)" "unprognostic (2.12e-4)" "unprognostic (4.40e-2)" 0.0 0.0 0.4 0.0 0.4 0.0 0.3 0.4 0.4 0.0 1.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 4.9 0.3 0.6 6.6 0.0 0.0 0.0 1.5 1.2 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 36.5 0.0 0.0 6.5 0.0 0.0 0.0 0.6 0.1 2.4 1.2 0.9 0.1 0.0 1.6 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.2 0.0 0.0 0.0 0.3 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 5.0 0.2 0.0 0.6 0.0 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.5 0.0 0.4 0.0 0.2 2.3 0.7 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.4 0.4 0.3 0.6 1.5 1.2 0.7 0.6 0.9 0.8 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 2.4 1.0 0.4 5.8 0.0 0.0 0.0 2.1 0.0 0.0 0.0 13.7 0.0 14.1 0.0 0.0 0.8 0.0 0.0 1.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.5 2.0 0.0 0.0 0.0 0.0 37.6 0.0 0.1 0.0 3.7 0.0 4.6 0.0 1.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 40.3 0.0 0.1 0.8 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ESX1 "ESX1L, ESXR1" ENSG00000123576 "ESX homeobox 1" Q8N693 X 104250038-104254933 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 69 "testis: 8.9" "Cell type enriched" "Detected in some" 25 "Spermatogonia: 98.0" "Cancer enriched" "Detected in single" 5 "testis cancer: 0.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 11 "TIME: 24.9" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA051992, HPA073330" Enhanced Supported "Nuclear speckles" NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Nuclear speckles" "HPA051992: AB_2681684, HPA073330: " "unprognostic (1.87e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 24.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 98.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 ETS1 "ETS-1, EWSR2, FLJ10768" ENSG00000134954 "ETS proto-oncogene 1, transcription factor" P14921 11 128458761-128587558 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins, Transcription factors" "Immunity, Transcription, Transcription regulation" DNA-binding Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 328.8" "Cell type enhanced" "Detected in many" "Adipocytes: 263.1;dendritic cells: 378.9;Endothelial cells: 190.4;Hepatic stellate cells: 213.8;NK-cells: 399.6;T-cells: 323.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 352.9;JURKAT: 362.3;U-698: 462.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002575, HPA063230" Enhanced Enhanced Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 3: T-cells - Adaptive immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "CAB002575: AB_563721, HPA063230: AB_2684965" "unprognostic (1.76e-2)" "unprognostic (2.49e-1)" "unprognostic (3.18e-3)" "unprognostic (6.22e-2)" "unprognostic (3.07e-1)" "unprognostic (2.56e-1)" "unprognostic (1.24e-2)" "unprognostic (1.57e-1)" "unprognostic (1.35e-2)" "unprognostic (7.17e-2)" "unprognostic (2.46e-2)" "unprognostic (1.61e-1)" "prognostic unfavorable (1.30e-5)" "unprognostic (2.02e-1)" "unprognostic (3.08e-2)" "unprognostic (1.38e-1)" "unprognostic (5.48e-3)" 101.2 19.2 11.7 145.7 10.4 35.3 65.4 9.8 14.1 35.9 8.9 31.2 26.9 36.5 9.3 21.8 20.2 62.5 43.0 8.9 11.3 30.4 47.6 76.2 277.1 13.1 14.7 27.0 20.1 28.4 7.8 56.3 13.4 17.1 31.4 1.8 16.5 20.7 25.6 18.1 49.3 38.1 11.6 185.8 46.1 8.0 15.2 328.8 39.8 42.3 250.2 67.9 19.2 11.3 87.7 15.7 72.8 0.3 30.7 49.3 0.2 65.7 140.2 80.9 77.3 5.1 91.7 312.1 65.7 109.5 184.7 29.8 7.0 190.0 169.0 66.6 1.1 352.9 6.4 0.3 82.2 36.7 4.0 97.2 15.0 69.6 252.2 46.1 67.9 362.3 0.6 63.3 98.1 0.0 185.7 27.4 27.0 7.9 55.0 50.4 118.7 24.5 64.2 95.6 0.9 5.0 34.5 0.7 73.6 48.5 0.3 17.7 126.1 180.5 57.1 35.5 109.1 46.7 8.9 462.5 32.2 68.0 162.1 51.2 0.1 6.6 20.4 0.3 28.9 12.3 27.0 25.0 0.2 9.2 32.5 26.1 1.1 27.8 1.0 6.2 33.3 9.5 11.7 10.4 9.8 14.1 8.9 11.3 13.1 14.7 13.4 11.6 15.2 11.3 263.1 25.6 26.5 2.9 125.6 114.8 41.0 12.4 1.8 0.0 8.2 7.2 9.0 4.3 24.3 11.0 0.0 0.2 378.9 13.1 0.0 31.9 6.2 26.3 51.0 190.4 15.5 13.7 2.0 22.6 0.5 45.5 17.3 66.2 19.6 1.3 213.8 5.4 7.3 0.0 25.6 15.0 10.2 18.3 48.2 1.5 14.0 12.5 69.4 65.6 16.8 0.2 399.6 55.3 9.5 99.3 6.6 15.4 129.6 26.8 2.2 4.6 5.9 0.2 105.2 55.5 76.6 0.7 1.8 1.5 63.2 0.4 323.2 40.4 5.8 32.6 ETS2 ENSG00000157557 "ETS proto-oncogene 2, transcription factor" P15036 21 38805183-38824955 "Predicted intracellular proteins, RAS pathway related proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 701.0;Basal squamous epithelial cells: 863.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "dendritic cells: 33.6;granulocytes: 37.0;monocytes: 32.4" "Cell line enhanced" "Detected in many" "HEL: 309.0;hTCEpi: 269.6;hTERT-HME1: 210.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003176 Enhanced "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 36: HEL - Hemostasis" "Cluster 41: Macrophages - Immune response" Nucleoplasm "Plasma membrane, Cytosol" "HPA003176: AB_2666824" "unprognostic (2.06e-1)" "unprognostic (5.91e-2)" "unprognostic (9.16e-3)" "unprognostic (5.33e-3)" "unprognostic (1.38e-1)" "unprognostic (1.58e-1)" "unprognostic (1.88e-3)" "unprognostic (7.36e-2)" "unprognostic (8.99e-3)" "unprognostic (3.66e-2)" "unprognostic (1.02e-1)" "unprognostic (1.77e-1)" "unprognostic (1.95e-2)" "unprognostic (2.12e-1)" "unprognostic (1.89e-1)" "unprognostic (8.10e-2)" "unprognostic (7.10e-2)" 109.9 29.7 51.4 95.5 43.3 167.1 87.7 31.6 72.5 89.6 61.4 119.3 131.3 77.5 27.9 90.6 72.5 132.1 68.0 50.9 43.2 66.1 230.7 185.5 38.0 50.0 39.9 65.7 37.5 61.9 56.6 73.6 45.0 80.1 146.5 7.5 50.3 45.7 149.7 248.3 179.7 78.0 47.9 201.0 72.7 7.6 54.0 43.7 62.5 42.8 34.8 210.2 103.6 44.4 120.1 26.2 16.6 5.6 18.8 61.3 49.2 27.4 154.1 36.2 46.5 23.0 35.1 24.7 13.3 25.0 48.5 35.7 28.0 71.2 63.8 24.5 12.0 309.0 152.6 62.2 196.9 18.4 28.2 39.8 269.6 49.6 210.2 22.0 28.3 17.2 31.3 0.2 14.4 20.1 54.1 22.2 56.0 39.3 18.2 189.6 10.2 25.2 50.2 74.4 14.2 18.4 78.4 32.8 6.2 5.7 1.9 36.3 30.8 83.0 13.0 55.3 60.5 0.5 0.3 25.2 20.7 69.4 70.8 21.0 19.5 7.0 3.2 24.9 3.9 0.4 3.0 4.7 33.6 0.4 3.2 3.2 37.0 0.3 32.4 8.1 0.3 8.9 51.4 43.3 31.6 72.5 50.9 43.2 50.0 39.9 45.0 47.9 54.0 44.4 253.0 51.3 156.6 6.2 10.8 427.4 701.0 150.8 863.4 2.1 84.2 69.7 25.6 51.5 141.9 51.5 0.0 58.4 17.5 150.7 11.7 73.7 4.0 241.1 127.4 312.7 91.8 36.4 39.6 108.5 109.3 98.7 161.1 497.9 51.3 0.9 242.0 262.4 62.1 0.0 10.7 266.0 79.3 150.8 291.7 2.0 18.0 253.4 67.6 74.0 41.0 1.5 3.1 4.0 3.1 127.6 175.1 24.8 21.0 184.0 162.2 47.2 107.9 1.6 52.6 81.8 108.8 0.6 3.3 522.6 486.4 177.6 28.8 8.2 243.3 338.7 ETV2 ER71 ENSG00000105672 "ETS variant transcription factor 2" O00321 19 35641745-35644871 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 5 "testis: 19.0" "Group enriched" "Detected in many" 10 "Early spermatids: 146.6;Late spermatids: 443.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in many" 6 "plasmacytoid DC: 24.4" "Lineage enriched" "Detected in all" 6 "dendritic cells: 24.4" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 71: Testis - DNA repair" "Cluster 17: WM-115 - Nervous system development" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (1.14e-1)" "unprognostic (3.24e-2)" "unprognostic (1.73e-1)" "unprognostic (5.44e-2)" "unprognostic (1.30e-1)" "unprognostic (2.53e-3)" "unprognostic (1.42e-1)" "unprognostic (2.77e-1)" "unprognostic (2.83e-1)" "unprognostic (2.69e-3)" "unprognostic (8.17e-3)" "unprognostic (1.18e-1)" "unprognostic (1.12e-1)" "unprognostic (4.20e-4)" "unprognostic (2.48e-1)" "unprognostic (1.41e-1)" "unprognostic (2.74e-1)" 1.5 2.1 0.6 0.7 0.6 0.5 1.2 2.2 1.0 1.8 0.6 1.5 2.0 0.9 0.1 3.6 1.0 0.3 0.7 0.6 0.8 1.8 2.7 1.1 0.6 0.9 0.7 1.4 3.6 1.2 1.3 0.3 0.9 1.5 0.4 0.4 2.3 0.6 0.2 3.4 1.5 0.3 0.7 1.0 1.7 19.0 0.6 0.4 1.1 0.0 0.2 1.0 2.1 0.6 1.4 1.9 1.2 1.5 1.4 2.7 0.2 0.5 0.8 1.4 2.2 0.7 0.7 0.2 2.0 1.0 0.3 0.5 0.1 1.0 0.1 2.3 2.3 2.6 1.1 1.3 2.4 0.8 3.4 2.4 2.0 0.7 1.1 0.8 0.4 0.8 0.8 1.0 0.8 1.7 1.2 0.8 0.1 2.3 0.6 1.7 3.1 2.0 2.1 1.3 1.6 1.1 1.7 0.3 3.0 0.3 1.2 3.0 0.4 4.2 2.1 2.3 1.7 1.1 2.5 0.4 2.0 0.9 4.1 0.0 2.2 1.1 3.1 3.3 3.4 2.3 3.8 3.9 2.6 1.2 2.1 2.7 0.8 1.0 3.8 24.4 3.3 1.8 0.6 0.6 2.2 1.0 0.6 0.8 0.9 0.7 0.9 0.7 0.6 0.6 2.4 0.0 1.1 0.0 2.8 5.7 3.5 8.4 12.0 5.1 9.0 12.2 1.4 4.3 2.6 5.5 0.0 1.9 7.0 12.1 7.9 1.9 146.6 1.7 2.7 2.4 7.7 1.7 0.0 5.3 2.8 3.3 2.6 3.4 1.3 1.0 4.6 19.9 2.2 0.0 0.1 9.7 2.0 2.0 5.1 443.3 9.0 2.8 1.8 0.0 2.0 3.1 1.0 0.0 0.1 1.7 4.8 2.6 8.4 3.3 28.6 20.9 1.1 2.8 0.0 6.7 2.3 6.7 2.8 11.3 12.9 1.9 3.6 3.5 7.1 6.1 EVX1 ENSG00000106038 "Even-skipped homeobox 1" P49640 7 27242700-27250493 "Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 2.9;prostate: 3.8;seminal vesicle: 2.9;urinary bladder: 3.3;vagina: 3.5" "Group enriched" "Detected in some" 33 "Early spermatids: 62.0;Late spermatids: 73.3" "Cancer enhanced" "Detected in some" "urothelial cancer: 2.6" "Region enhanced" "Detected in single" "medulla oblongata: 1.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 16 "OE19: 25.2;RT4: 16.1" "Region enhanced" "Detected in single" "pons and medulla: 1.0" "Not detected" "Not detected" HPA055132 Approved Nucleoplasm NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 21: OE19 - Mitochondria" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "HPA055132: AB_2682707" "unprognostic (2.73e-2)" "unprognostic (3.59e-1)" "unprognostic (4.31e-1)" "unprognostic (5.16e-2)" "unprognostic (1.76e-3)" "unprognostic (2.08e-2)" "unprognostic (8.48e-3)" "unprognostic (5.94e-2)" "unprognostic (1.26e-8)" "unprognostic (2.94e-1)" "unprognostic (1.39e-1)" "unprognostic (9.12e-2)" "unprognostic (1.83e-2)" 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.9 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.7 0.8 0.0 0.0 0.0 0.0 0.1 0.9 3.8 0.3 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 3.3 3.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.2 0.2 0.0 0.0 0.0 0.0 16.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.7 0.8 0.9 0.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.1 62.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 73.3 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.5 0.0 0.0 0.0 0.0 0.0 0.1 2.0 EVX2 ENSG00000174279 "Even-skipped homeobox 2" Q03828 2 176077472-176083913 "Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 1.4;prostate: 1.3;seminal vesicle: 1.6;testis: 3.0" "Cell type enhanced" "Detected in some" "Early spermatids: 8.7;Enteroendocrine cells: 2.4;Late spermatids: 4.7;Paneth cells: 1.7" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "midbrain: 1.3;pons and medulla: 1.1" "Not detected" "Not detected" HPA041576 Uncertain NA NA "Cluster 21: Non-specific - Transcription" "Cluster 29: Early spermatids - Spermatogenesis" "HPA041576: AB_10796347" "unprognostic (2.27e-1)" "unprognostic (1.68e-3)" "unprognostic (1.83e-1)" "unprognostic (3.41e-1)" "unprognostic (5.75e-1)" "unprognostic (3.13e-2)" "unprognostic (2.15e-3)" "unprognostic (2.32e-1)" "unprognostic (4.93e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.4 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.1 0.0 0.0 0.0 0.0 0.0 1.0 1.3 0.6 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.5 1.1 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 8.7 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.2 0.0 0.0 0.0 0.0 0.0 1.2 0.3 EXD1 "EXDL1, MGC33637" ENSG00000178997 "Exonuclease 3'-5' domain containing 1" Q8NHP7 15 41182725-41230757 "Predicted intracellular proteins" "Meiosis, RNA-mediated gene silencing" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "testis: 14.9" "Cell type enhanced" "Detected in some" "Collecting duct cells: 3.7;Early spermatids: 13.4;Late spermatids: 5.7;Spermatocytes: 23.6" "Not detected" "Not detected" "Region enriched" "Detected in single" 4 "pons: 1.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (1.12e-1)" "unprognostic (6.33e-3)" "unprognostic (2.51e-2)" "unprognostic (2.29e-1)" "unprognostic (1.45e-1)" "unprognostic (1.21e-2)" "unprognostic (6.50e-2)" "unprognostic (4.57e-2)" "unprognostic (4.54e-2)" "unprognostic (2.15e-1)" "unprognostic (9.55e-2)" "unprognostic (1.92e-1)" "unprognostic (2.11e-6)" "unprognostic (2.15e-1)" "unprognostic (2.29e-1)" "unprognostic (2.72e-1)" "unprognostic (2.71e-2)" 0.3 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 14.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.4 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.4 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.3 0.1 0.1 0.3 0.2 1.5 0.2 0.2 0.3 0.1 0.0 1.1 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.3 0.3 0.5 0.0 0.6 3.7 0.0 0.0 0.1 0.0 0.0 0.0 13.4 0.2 0.1 0.1 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.5 0.0 0.0 0.0 1.6 5.7 0.0 0.2 1.8 1.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.2 0.1 23.6 2.5 0.0 0.1 0.0 0.1 0.1 0.0 0.0 EXOC1L ENSG00000250821 "Exocyst complex component 1 like" A0A1B0GW35 4 55819790-55837489 "Predicted intracellular proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 8 "Theca cells: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 20 "NK-cell: 1.9" "Lineage enriched" "Detected in single" 20 "NK-cells: 1.9" "Cell line enhanced" "Detected in single" "HEK 293: 1.5" "Region enriched" "Detected in single" 4 "pons and medulla: 2.8" "Not detected" "Not detected" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.3 0.2 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.5 0.0 0.0 EXOSC4 "FLJ20591, hRrp41p, p12A, RRP41, RRP41A, Rrp41p, SKI6, Ski6p" ENSG00000178896 "Exosome component 4" Q9NPD3 8 144078648-144080648 "Plasma proteins, Predicted intracellular proteins" "rRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 94.9" "Group enriched" "Detected in many" 4 "Early spermatids: 320.6;Late spermatids: 856.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "PC-3: 430.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024792, HPA065103" Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 71: Testis - DNA repair" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" Vesicles "HPA024792: AB_1848325, HPA065103: " "unprognostic (2.32e-1)" "unprognostic (1.55e-2)" "unprognostic (3.06e-1)" "unprognostic (3.53e-2)" "unprognostic (1.33e-1)" "unprognostic (2.29e-2)" "unprognostic (6.58e-3)" "unprognostic (1.26e-1)" "unprognostic (8.36e-2)" "prognostic favorable (2.23e-4)" "unprognostic (4.32e-2)" "unprognostic (1.41e-1)" "unprognostic (2.30e-2)" "unprognostic (5.18e-2)" "unprognostic (1.23e-1)" "unprognostic (2.71e-1)" "unprognostic (5.11e-2)" 19.3 31.2 15.1 11.4 16.5 14.9 16.9 16.0 23.4 13.1 16.1 18.8 15.4 17.0 5.0 27.5 16.1 7.2 23.7 15.6 15.0 23.6 35.0 16.0 12.1 16.8 14.9 12.3 18.8 10.3 17.6 9.2 15.5 18.8 5.7 3.5 26.6 12.5 21.2 22.1 15.2 6.1 15.4 23.8 24.0 94.9 15.8 10.1 13.9 8.2 6.6 17.4 15.2 15.9 51.8 104.8 18.1 44.2 15.6 11.7 51.8 39.9 15.2 28.9 28.9 73.4 33.4 28.9 54.6 15.5 21.0 40.4 33.8 40.5 8.3 42.5 117.8 42.7 77.9 83.3 25.9 31.4 48.6 16.9 40.9 33.2 26.2 11.4 14.8 32.0 68.8 19.8 23.8 177.8 51.4 62.0 47.6 51.2 430.6 21.7 30.2 74.8 27.7 48.3 57.6 75.4 46.6 59.7 95.4 9.3 68.1 49.0 15.2 29.9 66.3 73.6 68.1 52.4 67.8 37.5 43.1 50.8 47.7 61.5 78.3 34.1 37.4 76.6 38.7 59.7 29.3 37.4 75.0 60.2 37.7 36.2 22.9 45.6 43.0 97.4 36.1 49.5 15.1 16.5 16.0 23.4 15.6 15.0 16.8 14.9 15.5 15.4 15.8 15.9 16.3 9.6 21.3 2.9 17.8 94.4 45.2 58.6 45.5 10.0 40.7 41.4 22.3 24.3 31.9 27.6 8.4 48.2 17.2 46.6 123.3 50.6 320.6 23.8 28.3 25.5 25.9 24.6 3.2 46.3 44.2 24.7 25.0 18.8 14.0 21.0 19.2 54.9 44.7 6.7 3.3 35.6 48.8 29.8 40.7 856.7 18.6 29.9 35.6 0.0 45.7 23.5 14.4 3.0 3.6 61.7 52.4 21.1 32.5 55.5 41.0 102.5 31.7 8.2 13.1 14.7 43.5 97.0 34.7 48.1 87.9 48.2 12.8 37.8 47.1 48.7 EXOSC9 "p5, p6, PM/Scl-75, PMSCL1, RRP45, Rrp45p" ENSG00000123737 "Exosome component 9" Q06265 4 121801318-121817021 "Disease related genes, Predicted intracellular proteins" "rRNA processing" RNA-binding "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 154.0;Spermatocytes: 170.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041838, HPA048257, CAB070171" Approved Enhanced Nucleoplasm,Nucleoli NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoli Nucleoplasm "CAB070171: AB_11026964, HPA041838: AB_10794492, HPA048257: AB_2680331" "unprognostic (7.36e-2)" "unprognostic (1.22e-2)" "unprognostic (2.81e-2)" "unprognostic (2.23e-1)" "unprognostic (2.78e-1)" "unprognostic (3.36e-2)" "prognostic unfavorable (1.04e-4)" "unprognostic (7.89e-2)" "unprognostic (3.73e-2)" "unprognostic (1.66e-2)" "unprognostic (9.25e-2)" "unprognostic (9.85e-3)" "prognostic unfavorable (6.49e-4)" "unprognostic (3.28e-2)" "unprognostic (6.66e-2)" "unprognostic (1.68e-1)" "unprognostic (7.21e-2)" 14.7 14.3 9.2 16.7 9.9 37.9 14.4 10.5 15.3 11.9 8.4 11.7 9.3 12.9 14.4 12.3 12.9 8.1 15.7 9.4 9.9 11.8 16.0 13.6 25.8 9.3 9.2 12.9 11.2 14.7 11.0 14.1 9.3 10.4 12.6 9.9 11.9 9.3 21.6 13.9 12.0 10.2 9.0 15.8 11.7 43.4 9.2 32.8 10.1 18.6 21.1 14.8 11.9 10.4 66.3 29.9 76.7 44.4 10.7 20.6 39.2 83.7 45.4 114.6 84.5 32.5 53.2 113.9 20.1 50.5 35.7 23.2 83.1 38.1 95.6 51.1 39.9 56.8 43.4 43.0 26.0 98.5 51.1 16.1 20.1 77.8 20.3 23.7 56.0 72.6 102.2 42.3 110.0 38.9 154.6 78.6 42.7 25.2 34.7 80.6 134.4 52.4 41.4 21.0 51.3 53.7 28.8 45.5 52.3 38.9 38.2 64.2 35.2 50.4 76.5 44.4 80.9 63.0 49.7 132.5 52.4 67.8 34.2 15.8 14.5 23.4 17.6 21.1 18.5 20.7 20.9 25.4 17.9 22.4 22.1 22.6 3.8 14.4 21.3 15.9 24.9 14.0 9.2 9.9 10.5 15.3 9.4 9.9 9.3 9.2 9.3 9.0 9.2 10.4 20.4 44.8 19.1 4.9 20.8 12.7 15.5 31.7 18.8 10.7 6.7 10.7 13.2 17.2 25.4 3.7 10.4 31.4 21.5 5.7 1.9 23.7 154.0 10.9 15.6 17.6 6.0 27.0 10.4 30.5 31.3 15.8 7.7 11.8 31.0 25.4 10.0 5.5 24.5 16.8 8.8 9.8 28.5 11.9 10.1 21.8 13.1 16.3 8.8 11.2 22.2 15.3 16.5 6.6 10.9 20.2 9.2 10.9 22.9 8.4 6.5 8.5 16.8 17.7 6.6 23.4 21.8 170.4 62.8 14.1 14.8 10.9 26.2 16.5 11.6 12.1 F13A1 F13A ENSG00000124491 "Coagulation factor XIII A chain" P00488 6 6144084-6321013 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Acyltransferase, Transferase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 232.8;placenta: 489.2" "Cell type enhanced" "Detected in many" "Hofbauer cells: 863.3;Langerhans cells: 205.1;Macrophages: 232.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 141.1;myeloid DC: 179.6" "Group enriched" "Detected in many" 184 "dendritic cells: 179.6;granulocytes: 50.2;monocytes: 141.1" "Cell line enhanced" "Detected in some" "AF22: 24.0;LHCN-M2: 8.9;RH-30: 43.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "HPA001804, CAB002155" Enhanced "Secreted to blood" NA NA 1400000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 4: Macrophages - Innate immune response" "CAB002155: AB_564077, HPA001804: AB_1078792" "unprognostic (4.44e-1)" "unprognostic (5.90e-2)" "unprognostic (2.65e-2)" "unprognostic (3.93e-2)" "unprognostic (5.02e-2)" "unprognostic (3.75e-2)" "unprognostic (5.27e-2)" "unprognostic (1.96e-1)" "unprognostic (2.68e-2)" "unprognostic (6.84e-3)" "unprognostic (4.96e-2)" "unprognostic (1.97e-1)" "prognostic unfavorable (6.61e-6)" "unprognostic (2.79e-2)" "unprognostic (1.52e-1)" "unprognostic (1.57e-1)" "unprognostic (2.54e-3)" 232.8 57.9 2.6 52.3 4.2 16.1 46.9 1.3 13.0 50.4 28.5 45.9 9.7 18.5 5.6 51.2 29.1 52.7 39.2 2.1 3.6 21.0 3.0 38.7 30.0 8.3 4.6 10.7 10.0 13.3 8.1 489.2 6.9 8.8 63.9 21.6 18.8 13.4 10.3 22.7 22.0 89.6 2.6 8.8 25.4 17.8 3.7 20.9 17.1 32.8 12.5 144.5 12.1 4.0 0.0 0.1 24.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 8.9 0.0 0.1 0.2 0.0 0.0 0.0 0.0 43.8 0.8 0.0 0.0 0.3 0.3 0.1 0.0 0.0 0.1 0.0 4.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 50.2 141.1 1.4 0.5 25.4 0.6 0.4 0.3 0.4 179.6 0.4 0.4 0.2 32.9 0.3 0.7 12.5 0.3 364.9 2.6 4.2 1.3 13.0 2.1 3.6 8.3 4.6 6.9 2.6 3.7 4.0 2.0 0.0 1.9 0.3 1.8 18.7 0.0 0.0 0.6 0.1 0.3 0.4 10.6 5.7 0.0 0.0 0.0 5.0 4.5 0.0 0.0 0.0 5.1 0.6 10.6 3.8 0.0 1.3 3.9 0.0 5.6 13.7 0.0 0.4 1.3 0.0 2.9 0.9 863.3 0.0 1.4 0.0 0.0 92.4 205.1 5.8 4.4 232.0 19.6 64.6 53.1 0.9 6.2 0.5 0.7 0.1 0.0 0.7 1.2 0.0 0.0 11.0 2.2 6.5 59.2 2.5 3.3 1.6 0.9 1.2 15.2 10.1 2.6 0.4 0.0 0.1 FAAP24 "C19orf40, FLJ46828, MGC32020" ENSG00000131944 "FA core complex associated protein 24" Q9BTP7 19 32972209-32978229 "Predicted intracellular proteins" "DNA damage, DNA repair" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 14.6;Spermatocytes: 22.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041168 Uncertain Supported Nucleoplasm,Vesicles NA NA "Cluster 11: Basophils - Unknown function" "Cluster 51: Non-specific - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Vesicles "HPA041168: AB_10960496" "unprognostic (1.18e-2)" "unprognostic (1.22e-2)" "unprognostic (1.34e-1)" "prognostic unfavorable (4.38e-4)" "unprognostic (6.52e-2)" "unprognostic (2.73e-1)" "unprognostic (2.58e-3)" "unprognostic (3.76e-2)" "unprognostic (1.88e-2)" "unprognostic (3.98e-2)" "unprognostic (2.82e-3)" "unprognostic (3.54e-2)" "prognostic unfavorable (4.00e-7)" "unprognostic (4.37e-3)" "unprognostic (5.30e-1)" "unprognostic (2.31e-3)" "unprognostic (2.15e-1)" 1.7 1.4 0.8 2.6 0.7 3.5 1.8 1.2 1.1 1.0 1.1 1.7 1.8 1.3 2.4 1.8 1.4 2.3 0.7 0.8 0.6 1.2 1.4 1.4 3.1 1.4 0.6 2.5 0.9 0.4 0.8 1.6 1.0 4.8 2.5 0.5 1.2 1.1 0.5 2.8 2.2 1.5 0.4 2.4 1.4 6.2 0.9 2.6 1.8 0.2 3.5 1.5 1.2 2.2 6.0 15.0 5.7 9.3 3.2 6.3 4.9 7.7 8.2 14.5 18.8 10.3 9.7 7.0 11.2 3.2 11.4 4.2 11.7 5.9 11.5 19.4 5.4 15.3 5.8 7.6 1.7 5.2 7.5 3.5 3.5 9.0 5.3 2.3 5.9 11.2 8.2 7.1 11.1 6.7 11.6 7.1 2.6 8.7 6.7 10.2 5.1 3.9 2.9 3.6 5.9 4.9 8.7 9.9 6.1 6.2 6.6 13.7 3.5 14.2 6.6 6.2 7.2 5.5 12.4 9.6 10.1 11.9 9.6 15.3 5.7 8.8 3.2 6.9 3.8 6.4 4.0 4.9 3.6 6.2 3.6 5.2 13.9 7.1 7.8 6.9 5.6 3.2 0.8 0.7 1.2 1.1 0.8 0.6 1.4 0.6 1.0 0.4 0.9 2.2 1.7 3.2 1.1 0.0 3.0 0.0 3.3 0.0 1.8 1.5 3.9 3.6 0.5 2.8 1.3 3.7 2.1 11.1 6.5 1.2 1.9 1.6 7.2 4.4 3.0 2.1 1.2 7.4 0.0 8.0 14.6 3.1 0.5 6.3 1.3 7.1 3.6 0.4 8.2 5.0 0.0 2.4 0.0 5.1 0.0 12.3 3.4 3.5 0.0 0.0 7.0 0.6 2.1 0.0 0.0 4.2 2.4 3.4 2.6 3.2 3.5 1.0 0.0 1.0 0.0 2.7 2.2 22.6 8.3 2.7 0.0 5.1 2.5 5.8 2.7 2.6 FABP3 "FABP11, H-FABP, MDGI, O-FABP" ENSG00000121769 "Fatty acid binding protein 3" P05413 1 31365253-31376850 "Candidate cardiovascular disease genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 14 "heart muscle: 5666.1;skeletal muscle: 2202.5;tongue: 1442.4" "Cell type enhanced" "Detected in many" "Breast glandular cells: 629.8;Cardiomyocytes: 2495.2;Distal tubular cells: 452.0;Proximal tubular cells: 703.6" "Cancer enhanced" "Detected in all" "renal cancer: 92.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 4 "ASC TERT1: 215.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017830, HPA055754" Enhanced Uncertain "Golgi apparatus,Plasma membrane,Focal adhesion sites" NA NA 1640000 3000000 "Cluster 22: NK-cells - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 30: Mammary glandular cells - Lactation" "Focal adhesion sites" "Golgi apparatus, Plasma membrane" "CAB017830: , HPA055754: AB_2682909" "unprognostic (2.07e-2)" "unprognostic (2.50e-2)" "unprognostic (1.32e-3)" "unprognostic (1.73e-2)" "unprognostic (2.05e-1)" "unprognostic (1.62e-1)" "unprognostic (6.07e-3)" "unprognostic (1.04e-1)" "unprognostic (6.86e-2)" "unprognostic (1.18e-1)" "unprognostic (2.85e-1)" "unprognostic (1.67e-1)" "prognostic favorable (1.54e-7)" "unprognostic (5.80e-3)" "unprognostic (3.45e-1)" "unprognostic (7.38e-3)" "unprognostic (9.76e-3)" 31.4 63.5 33.7 2.1 39.2 1.6 95.4 42.3 51.5 40.4 14.8 16.3 0.8 93.9 6.4 9.5 37.2 3.7 5666.1 52.0 37.3 229.8 6.6 26.4 3.4 50.5 38.3 20.3 2.2 0.3 9.0 2.8 55.2 48.9 4.8 17.8 46.5 52.2 2202.5 16.3 7.5 44.2 31.4 28.8 60.3 15.3 36.1 2.3 6.8 1442.4 1.4 12.5 32.5 36.8 1.0 0.4 8.8 1.1 50.6 215.0 2.0 2.6 17.3 0.3 6.6 1.3 1.9 1.6 17.8 5.2 0.3 2.1 2.5 0.0 0.5 0.8 3.7 1.8 2.7 5.3 2.2 1.7 0.5 16.9 0.0 3.9 0.0 2.5 0.0 1.4 2.2 0.5 2.2 0.5 0.7 1.5 11.4 0.9 3.1 0.4 5.7 0.6 4.1 0.7 2.1 0.5 1.5 0.7 28.4 13.2 0.9 3.1 1.7 1.0 1.0 6.0 1.3 1.0 2.3 1.3 2.9 1.5 1.7 0.0 0.1 0.0 0.2 0.2 0.2 0.2 0.1 0.3 0.1 0.2 0.1 0.4 0.0 0.2 0.1 0.1 0.1 0.1 33.7 39.2 42.3 51.5 52.0 37.3 50.5 38.3 55.2 31.4 36.1 36.8 4.9 0.0 1.7 2.9 7.7 3.6 1.5 0.4 0.0 6.1 629.8 13.2 2495.2 2.8 1.3 27.6 2.1 3.8 2.1 0.4 452.0 0.4 2.5 0.4 0.5 25.6 0.0 0.0 16.1 0.4 1.4 67.2 1.1 3.1 1.3 43.8 2.2 0.1 114.7 8.4 14.6 0.1 0.0 27.8 10.3 5.4 6.8 19.1 8.8 3.7 0.0 2.6 0.0 3.5 8.9 0.3 12.3 7.9 0.1 6.8 0.1 703.6 1.5 10.2 0.0 14.9 40.7 2.9 0.2 0.2 3.0 1.6 5.1 97.9 0.3 36.5 FADS1 "D5D, FADS6, FADSD5, LLCDL1, TU12" ENSG00000149485 "Fatty acid desaturase 1" O60427 11 61799627-61829318 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Transport" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 91.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC TERT1: 521.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042705 Approved NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 65: Plasmacytoid DCs - Unknown function" "HPA042705: AB_10795709" "unprognostic (8.28e-2)" "unprognostic (3.54e-1)" "unprognostic (1.29e-1)" "unprognostic (1.99e-1)" "unprognostic (8.17e-3)" "unprognostic (1.40e-1)" "unprognostic (1.99e-2)" "unprognostic (3.23e-3)" "unprognostic (7.88e-2)" "unprognostic (1.94e-2)" "unprognostic (4.10e-2)" "unprognostic (2.00e-1)" "prognostic unfavorable (1.95e-9)" "unprognostic (2.29e-2)" "unprognostic (3.59e-2)" "prognostic unfavorable (2.79e-4)" "prognostic unfavorable (1.33e-4)" 26.2 67.7 43.1 19.8 39.2 9.7 13.6 38.4 40.7 19.6 70.7 9.5 5.5 21.3 6.6 5.2 17.4 14.5 22.6 39.3 58.5 9.7 52.8 20.3 9.8 57.9 62.1 27.5 10.0 27.2 21.3 21.1 52.2 19.6 4.9 35.1 6.4 15.8 17.5 15.5 6.7 20.5 46.4 8.0 9.4 11.9 68.7 8.1 6.0 7.8 9.2 12.7 10.2 56.0 66.3 170.1 159.1 41.1 313.2 521.2 46.4 42.0 204.5 69.9 118.9 53.3 143.2 2.3 43.4 60.5 177.2 84.7 130.8 114.1 51.7 12.2 18.4 107.9 191.2 98.9 169.1 23.4 10.4 238.1 38.3 154.7 74.7 73.8 64.1 104.7 59.9 118.6 70.1 18.6 78.6 23.6 94.2 5.5 63.0 85.4 162.5 231.2 81.5 29.0 80.7 89.6 106.7 1.7 90.0 58.4 38.6 98.6 62.1 71.8 70.8 74.2 50.6 112.9 111.3 55.4 42.6 108.9 61.4 7.5 33.2 6.2 12.1 40.4 2.6 2.5 4.0 4.9 28.0 8.7 2.3 5.4 2.6 6.9 17.4 23.6 2.9 15.7 43.1 39.2 38.4 40.7 39.3 58.5 57.9 62.1 52.2 46.4 68.7 56.0 10.3 6.4 77.9 28.7 3.2 2.7 2.5 48.5 1.2 78.9 2.6 3.7 30.4 8.6 25.3 12.9 27.1 9.5 12.4 0.9 0.0 15.2 8.7 4.9 30.7 16.6 9.7 46.3 9.4 33.4 50.0 34.9 6.1 7.8 37.9 65.3 9.3 74.5 37.2 69.0 14.7 0.6 16.2 21.7 21.0 16.4 29.8 27.6 32.0 12.2 32.0 70.5 6.2 13.6 27.4 7.6 0.0 21.4 2.1 6.4 0.1 1.1 8.0 91.9 0.0 40.3 31.9 6.5 17.5 2.3 1.4 9.3 5.5 75.2 1.4 1.6 FAF1 "CGI-03, hFAF1, HFAF1s, UBXD12, UBXN3A" ENSG00000185104 "Fas associated factor 1" Q9UNN5 1 50437028-50960267 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Apoptosis "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 202.4;Excitatory neurons: 296.7;Inhibitory neurons: 278.9;Microglial cells: 177.1;Oligodendrocyte precursor cells: 269.9;Oligodendrocytes: 424.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018253, CAB072814" Approved Supported Nucleoplasm NA NA 12000 "Cluster 26: Non-specific - Mitochondria" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "CAB072814: , HPA018253: AB_1848351" "unprognostic (1.52e-1)" "unprognostic (1.25e-2)" "unprognostic (6.49e-3)" "unprognostic (4.69e-2)" "unprognostic (6.35e-2)" "unprognostic (1.19e-2)" "prognostic unfavorable (1.87e-5)" "unprognostic (2.51e-1)" "unprognostic (1.02e-1)" "unprognostic (1.82e-1)" "unprognostic (9.52e-2)" "unprognostic (1.58e-1)" "unprognostic (1.58e-1)" "unprognostic (1.17e-1)" "unprognostic (9.00e-2)" "unprognostic (2.01e-3)" "unprognostic (6.42e-3)" 18.2 16.8 21.0 9.2 22.0 21.0 18.5 21.8 27.5 18.9 18.7 23.7 12.4 18.2 11.7 23.1 15.7 8.7 34.9 22.3 22.1 21.5 23.6 14.9 13.1 21.5 21.5 19.9 26.2 23.2 20.6 10.6 22.0 18.5 12.7 19.6 18.1 16.3 67.9 28.1 16.4 13.4 21.8 14.0 18.2 47.8 21.2 22.2 18.3 37.6 14.1 21.4 18.7 25.9 37.4 27.1 23.1 39.3 22.4 21.1 33.9 35.5 32.1 53.9 48.8 30.4 26.0 59.9 25.7 30.5 47.5 27.2 37.3 33.1 45.9 40.1 33.5 49.9 33.5 31.6 36.4 54.3 28.5 19.8 29.4 57.0 69.4 27.8 29.5 44.5 58.9 0.2 28.1 15.0 56.6 43.0 30.6 49.3 19.2 52.1 50.7 0.0 54.9 33.1 0.3 28.6 32.3 64.9 56.4 32.0 20.4 64.1 18.2 30.4 37.3 37.8 0.2 45.1 50.6 69.3 0.0 77.6 35.7 1.1 2.1 4.9 4.0 2.7 5.5 2.5 3.6 4.0 3.6 4.2 4.3 2.8 0.7 4.3 3.5 2.9 6.1 1.6 21.0 22.0 21.8 27.5 22.3 22.1 21.5 21.5 22.0 21.8 21.2 25.9 17.9 6.4 18.2 202.4 26.9 21.4 38.5 27.8 33.6 19.9 16.9 16.9 43.9 11.5 27.2 16.5 27.1 14.2 18.0 13.1 29.4 8.8 75.1 15.1 15.6 14.2 11.4 44.6 296.7 11.6 28.2 16.0 29.0 16.9 5.7 19.2 10.4 18.2 11.4 16.8 278.9 17.8 6.1 13.6 18.0 117.2 11.1 15.4 16.0 177.1 8.9 20.0 15.5 269.9 424.4 8.5 9.7 10.9 35.4 18.3 20.0 28.3 32.7 33.0 6.6 26.2 20.3 36.9 15.6 37.9 28.1 15.3 27.9 19.6 21.6 34.1 FAH ENSG00000103876 "Fumarylacetoacetate hydrolase" P16930 15 80152490-80186946 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Phenylalanine catabolism, Tyrosine catabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 301.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 266.8;Proximal tubular cells: 305.5" "Cancer enhanced" "Detected in all" "liver cancer: 23.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 34.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HHSteC: 316.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041370, HPA044093" Enhanced Approved Nucleoplasm,Cytosol NA NA 220000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 32: U-937 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol Nucleoplasm "HPA041370: AB_2677438, HPA044093: AB_2678806" "unprognostic (3.15e-1)" "unprognostic (5.65e-2)" "unprognostic (1.64e-1)" "unprognostic (6.16e-2)" "unprognostic (2.33e-3)" "prognostic unfavorable (8.51e-4)" "unprognostic (1.19e-2)" "unprognostic (5.83e-2)" "unprognostic (2.51e-2)" "unprognostic (5.21e-2)" "unprognostic (1.80e-1)" "unprognostic (1.23e-1)" "unprognostic (2.17e-2)" "unprognostic (4.21e-2)" "unprognostic (2.99e-1)" "unprognostic (2.93e-1)" "unprognostic (8.98e-2)" 99.2 65.4 16.0 7.0 17.1 20.0 59.0 16.6 21.1 19.2 15.1 13.8 14.6 19.3 50.4 15.2 23.0 9.7 20.3 16.3 18.8 65.0 301.5 20.0 5.7 17.9 19.6 26.4 9.9 18.4 16.8 7.8 16.9 16.6 11.9 1.6 14.8 13.6 31.0 10.9 16.8 13.5 17.2 19.1 14.2 20.8 17.4 6.7 14.5 27.7 5.8 16.4 15.8 17.5 20.1 34.4 13.5 17.0 60.2 62.2 32.9 24.3 56.8 26.2 22.3 22.0 35.9 0.4 39.0 52.6 36.8 29.1 46.8 59.6 25.1 12.5 28.5 166.6 18.0 112.1 316.6 79.6 88.8 107.5 37.1 22.9 39.7 84.2 37.4 38.3 71.1 35.7 50.3 31.0 22.3 42.0 9.9 15.5 37.6 12.2 19.3 123.4 77.0 25.2 0.7 8.3 27.4 76.7 77.9 21.6 58.3 55.0 126.1 46.8 30.0 25.5 42.7 32.7 69.5 13.8 99.6 187.5 26.9 34.5 18.8 3.3 9.6 8.1 2.3 0.1 2.4 6.0 25.3 0.1 3.1 2.7 1.3 5.7 8.4 1.9 2.5 9.7 16.0 17.1 16.6 21.1 16.3 18.8 17.9 19.6 16.9 17.2 17.4 17.5 3.0 3.2 13.8 9.8 4.1 6.8 17.5 30.8 15.4 0.4 19.1 13.7 15.5 21.5 12.5 33.1 0.0 37.9 4.9 9.3 52.8 9.3 7.5 3.0 16.2 3.2 4.2 24.4 0.4 3.5 14.1 16.6 3.6 4.0 41.9 6.3 8.9 266.8 72.5 0.0 2.5 13.0 24.4 21.4 6.6 13.5 9.9 30.5 19.6 1.0 5.7 7.3 3.1 2.5 0.6 4.5 12.8 7.9 5.2 9.7 54.1 305.5 5.3 0.4 0.0 9.2 11.2 1.5 2.1 18.2 5.7 22.0 7.7 8.7 22.4 16.4 FAM102B "DKFZp779B126, SYM-3B" ENSG00000162636 "Family with sequence similarity 102 member B" Q5T8I3 1 108560089-108644900 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 54.9;Langerhans cells: 43.2;Microglial cells: 52.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028451 Uncertain Approved Nucleoli,Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 20: HeLa - Mitochondria" "Cluster 41: Macrophages - Immune response" "Nucleoli, Cytosol" "HPA028451: AB_10602497" "unprognostic (1.30e-1)" "unprognostic (2.19e-1)" "unprognostic (4.08e-3)" "unprognostic (3.87e-2)" "unprognostic (1.11e-1)" "unprognostic (3.68e-3)" "unprognostic (1.87e-3)" "unprognostic (3.10e-1)" "unprognostic (2.62e-2)" "unprognostic (1.32e-2)" "unprognostic (2.17e-1)" "unprognostic (4.11e-2)" "prognostic unfavorable (3.47e-6)" "unprognostic (1.06e-1)" "unprognostic (2.49e-1)" "unprognostic (1.21e-1)" "unprognostic (1.86e-1)" 9.1 3.9 8.1 10.5 9.7 21.2 10.7 5.1 9.2 7.4 0.1 13.3 11.0 6.5 4.2 6.0 5.1 14.7 6.6 9.4 8.6 3.2 4.9 7.8 9.0 4.1 6.8 5.3 3.8 7.5 3.8 5.9 8.1 6.3 14.6 3.6 13.7 7.8 1.3 3.7 11.2 8.8 3.0 8.8 7.6 8.6 5.6 8.7 3.5 6.0 8.2 16.4 4.4 5.0 6.9 4.9 9.7 5.2 17.0 10.2 6.4 4.0 5.4 6.1 10.3 1.8 6.8 7.6 3.6 10.4 6.3 13.1 33.2 1.4 7.8 5.1 4.8 10.6 35.8 0.8 4.3 14.0 19.8 5.5 1.4 9.0 0.5 12.3 4.0 12.5 26.3 41.2 14.4 28.4 9.0 10.0 7.6 16.2 24.6 20.8 24.5 1.6 1.7 7.9 31.4 9.3 15.9 27.4 8.3 6.8 5.8 22.5 0.7 9.8 18.4 8.6 15.5 7.6 1.9 7.1 14.4 10.8 5.3 2.9 0.4 0.4 0.3 0.9 0.2 0.3 0.3 0.4 1.0 0.3 0.2 0.2 0.3 0.2 0.3 0.2 0.3 0.1 8.1 9.7 5.1 9.2 9.4 8.6 4.1 6.8 8.1 3.0 5.6 5.0 5.9 0.0 2.2 12.1 6.1 6.1 2.3 1.0 4.6 3.9 10.1 7.2 1.9 10.0 2.2 1.8 0.0 2.4 17.2 15.6 1.9 2.7 15.3 2.1 7.8 5.5 7.2 3.8 54.9 6.1 2.7 16.3 6.6 5.2 7.6 3.6 8.2 1.2 9.7 0.0 27.9 8.1 0.0 25.1 43.2 6.9 14.3 27.5 5.4 52.5 15.2 1.2 11.3 25.1 7.2 4.5 10.5 20.7 11.9 1.9 4.5 1.0 1.8 1.1 0.0 3.2 6.5 4.4 6.4 6.5 3.7 3.4 16.4 36.2 13.8 4.6 FAM107A "DRR1, TU3A" ENSG00000168309 "Family with sequence similarity 107 member A" O95990 3 58564117-58627610 "Predicted intracellular proteins" "Cell cycle, Growth regulation, Stress response" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 12 "brain: 1923.8;choroid plexus: 1389.1" "Cell type enhanced" "Detected in many" "Adipocytes: 196.3;Astrocytes: 81.9;Endothelial cells: 121.3;Hepatic stellate cells: 150.6;Muller glia cells: 125.0" "Cancer enriched" "Detected in many" 6 "glioma: 110.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "ASC diff: 20.7;HUVEC TERT2: 64.9" "Low region specificity" "Detected in all" HPA055888 Enhanced Supported "Nuclear speckles" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nuclear speckles" "HPA055888: AB_2682957" "unprognostic (1.20e-2)" "unprognostic (1.19e-3)" "unprognostic (1.47e-2)" "prognostic unfavorable (3.56e-4)" "unprognostic (3.11e-1)" "unprognostic (7.80e-3)" "prognostic favorable (3.38e-4)" "unprognostic (1.92e-1)" "unprognostic (1.64e-1)" "unprognostic (5.73e-2)" "unprognostic (7.82e-3)" "unprognostic (2.22e-2)" "unprognostic (1.33e-2)" "unprognostic (1.33e-2)" "unprognostic (2.82e-1)" "unprognostic (1.92e-1)" "unprognostic (7.95e-3)" 73.2 7.5 1824.7 8.3 1801.2 0.3 58.6 1490.8 1923.8 34.5 1389.1 36.9 5.4 36.3 53.3 29.2 87.0 16.0 140.4 1745.7 1736.7 45.0 5.5 93.2 3.1 1611.9 1644.5 11.8 23.3 5.9 109.6 29.4 1613.0 80.5 16.0 85.1 40.6 38.0 26.3 23.3 45.2 42.5 1564.5 25.7 37.7 5.7 1698.7 43.9 51.4 32.8 8.6 68.9 41.6 1770.4 0.0 0.0 0.9 0.0 20.7 1.3 0.3 0.1 0.0 0.1 0.2 0.0 0.1 0.1 5.8 0.0 0.2 0.4 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.4 1.4 0.0 0.1 0.1 0.3 64.9 0.0 0.0 0.9 0.0 0.0 0.0 0.3 0.4 0.0 0.1 0.2 0.1 0.2 0.1 0.0 0.2 0.2 0.0 0.1 0.0 0.2 0.2 0.0 3.6 0.3 0.2 0.2 0.1 0.1 0.0 0.1 1.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1824.7 1801.2 1490.8 1923.8 1745.7 1736.7 1611.9 1644.5 1613.0 1564.5 1698.7 1770.4 196.3 6.4 5.5 81.9 0.5 2.2 50.8 0.3 2.2 5.2 2.3 1.3 26.5 4.3 3.2 38.6 52.1 0.1 0.4 0.0 9.8 1.1 14.5 23.2 2.4 121.3 3.6 2.7 1.4 0.2 0.0 18.4 0.0 39.3 1.3 5.9 150.6 1.6 0.0 3.3 5.3 0.0 0.0 2.2 3.7 32.4 32.9 1.9 5.4 14.0 0.0 125.0 0.0 2.0 0.6 0.3 0.0 11.7 1.3 7.3 0.2 4.5 2.3 50.2 6.6 6.6 10.4 0.7 0.4 0.4 2.7 0.0 1.0 0.5 0.0 2.2 FAM110D "FLJ14050, GRRP1" ENSG00000197245 "Family with sequence similarity 110 member D" Q8TAY7 1 26159079-26163962 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 12 "Adipocytes: 82.7;Endothelial cells: 63.5;Hepatic stellate cells: 34.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "TIME: 1.2;U-2 OS: 1.4;U-937: 1.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA013664 Approved NA NA "Cluster 11: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 9: U-2 OS - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA013664: AB_1234332" "unprognostic (7.53e-2)" "unprognostic (4.45e-3)" "unprognostic (4.80e-4)" "unprognostic (1.84e-2)" "unprognostic (1.07e-3)" "unprognostic (3.16e-3)" "unprognostic (7.67e-5)" "unprognostic (2.21e-1)" "unprognostic (1.66e-1)" "unprognostic (4.51e-2)" "unprognostic (7.29e-3)" "unprognostic (6.63e-2)" "unprognostic (9.87e-2)" "unprognostic (6.94e-2)" "unprognostic (2.91e-1)" "unprognostic (1.51e-1)" "unprognostic (2.96e-1)" 10.9 1.3 4.1 0.6 3.0 0.8 8.5 3.1 3.7 4.8 2.0 2.9 1.1 7.9 0.8 1.9 7.4 2.3 6.2 3.1 3.2 4.0 0.4 4.2 1.1 4.7 3.6 1.3 2.2 1.1 1.3 0.6 4.1 3.1 0.5 0.3 2.4 0.7 4.2 3.0 3.1 2.8 4.5 0.8 3.3 0.6 4.1 0.9 4.7 2.1 0.4 4.0 3.6 3.3 0.1 0.1 0.5 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.6 0.6 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.1 0.1 0.3 0.3 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.2 0.0 0.1 0.2 0.1 0.5 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.5 0.5 0.1 0.0 0.1 0.4 0.1 0.2 1.2 0.1 1.4 0.1 0.0 0.0 0.2 0.1 0.0 1.0 0.0 1.3 0.2 0.2 0.2 0.1 0.1 0.2 0.1 0.1 0.0 0.3 0.2 0.2 1.0 0.4 0.1 0.2 0.0 0.0 4.1 3.0 3.1 3.7 3.1 3.2 4.7 3.6 4.1 4.5 4.1 3.3 82.7 0.0 3.4 0.3 0.9 1.0 0.9 0.0 2.2 2.3 1.3 1.8 3.1 2.8 1.3 0.0 0.0 0.1 0.6 0.0 0.0 0.1 0.4 0.2 0.5 63.5 0.0 2.7 0.4 0.0 0.0 2.5 0.0 0.2 0.0 0.3 34.6 0.0 0.0 1.7 0.7 0.0 0.0 1.3 1.8 0.5 0.6 0.4 0.0 4.7 0.0 1.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 1.4 0.0 1.4 1.8 0.2 0.7 0.8 0.9 0.3 0.3 0.5 0.0 0.3 FAM122B "DKFZp686L20116, RP11-308B5.5" ENSG00000156504 "Family with sequence similarity 122B" Q7Z309 X 134769566-134797232 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000266 Enhanced Approved Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 32: U-937 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" Nucleoplasm "HPA000266: AB_1078801" "unprognostic (2.10e-3)" "unprognostic (1.55e-2)" "unprognostic (4.53e-3)" "prognostic unfavorable (7.19e-5)" "unprognostic (1.67e-1)" "unprognostic (2.19e-1)" "unprognostic (1.41e-2)" "unprognostic (3.07e-2)" "unprognostic (1.50e-2)" "unprognostic (2.15e-1)" "unprognostic (7.64e-2)" "unprognostic (1.53e-3)" "unprognostic (2.26e-3)" "unprognostic (2.60e-2)" "unprognostic (7.96e-2)" "unprognostic (2.11e-2)" "unprognostic (3.19e-3)" 16.0 19.5 23.9 18.4 25.4 31.6 15.8 20.6 32.8 18.7 27.1 18.1 15.4 20.8 26.0 17.6 22.6 13.1 14.6 23.9 24.3 20.1 11.2 17.6 29.8 22.8 23.5 28.8 16.8 21.1 21.3 15.5 22.1 17.6 22.7 8.8 18.8 16.0 7.8 19.4 22.1 19.5 24.3 27.4 20.1 35.3 29.2 25.9 21.0 7.1 27.3 18.8 17.6 25.2 51.0 46.2 36.2 25.9 18.2 23.6 25.4 39.5 34.5 43.9 41.3 41.1 44.3 49.7 76.2 28.9 61.3 33.5 54.0 32.6 79.2 61.8 37.4 50.2 94.6 13.4 11.2 92.9 61.2 15.5 31.6 48.3 21.0 28.5 25.9 50.0 33.2 61.9 46.8 68.8 58.1 80.1 19.8 58.3 49.1 58.0 39.5 43.6 26.6 52.1 32.9 23.3 21.2 28.3 14.8 31.1 15.2 47.4 18.6 36.4 23.5 93.3 87.1 34.1 42.2 63.2 39.0 105.8 46.2 0.0 0.4 2.6 0.8 0.2 1.1 0.7 0.7 1.0 0.5 0.6 0.9 1.2 0.5 1.2 0.5 1.5 0.8 0.5 23.9 25.4 20.6 32.8 23.9 24.3 22.8 23.5 22.1 24.3 29.2 25.2 4.7 12.8 10.4 6.2 17.4 13.5 15.0 9.2 12.0 4.0 11.8 7.6 10.8 2.8 11.7 16.5 12.5 9.3 15.3 14.4 17.6 8.0 1.3 10.4 6.7 12.5 6.0 32.6 15.2 13.8 10.2 11.0 15.3 11.5 23.6 32.9 9.7 7.4 14.7 13.5 10.5 13.2 18.3 21.4 21.7 5.8 10.5 17.9 17.8 12.2 16.6 6.4 20.6 8.0 16.8 12.2 20.2 6.4 13.8 14.7 12.9 8.0 8.2 5.5 0.0 6.6 8.8 3.7 4.4 14.4 11.2 8.8 20.1 17.7 12.2 19.1 FAM126A "DRCTNNB1A, HCC, HYCC1, hyccin" ENSG00000122591 "Family with sequence similarity 126 member A" Q9BYI3 7 22889371-23014130 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cataract, Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 133.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042873 Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" "Plasma membrane, Cytosol" "HPA042873: AB_2678207" "unprognostic (7.94e-2)" "unprognostic (2.53e-2)" "unprognostic (1.58e-3)" "unprognostic (1.02e-1)" "unprognostic (1.96e-1)" "unprognostic (7.38e-2)" "unprognostic (3.54e-4)" "unprognostic (1.35e-1)" "unprognostic (9.76e-3)" "unprognostic (1.30e-2)" "unprognostic (7.23e-2)" "unprognostic (6.19e-2)" "prognostic unfavorable (6.04e-7)" "prognostic unfavorable (5.99e-4)" "unprognostic (1.87e-1)" "unprognostic (2.40e-2)" "prognostic unfavorable (9.03e-4)" 14.9 4.7 5.0 8.5 6.9 4.2 12.2 4.4 6.5 9.7 7.9 9.7 9.4 8.7 1.4 12.2 6.7 11.4 10.5 12.1 4.5 4.7 8.5 13.7 11.5 5.0 5.9 6.6 6.2 2.3 5.0 14.8 5.4 5.9 4.4 4.9 6.8 4.8 25.0 4.9 6.9 11.5 4.5 11.8 4.6 12.0 6.3 4.2 6.6 15.3 9.2 9.4 11.2 7.8 22.4 12.4 63.6 22.3 61.3 100.9 10.6 103.0 101.8 41.6 63.9 19.8 10.6 13.3 15.9 82.6 87.2 7.7 44.3 14.7 72.6 6.6 22.4 14.7 18.1 13.0 48.0 19.3 15.7 41.1 9.2 85.0 61.3 83.4 42.5 7.5 30.4 58.6 77.5 7.9 10.8 24.2 63.0 0.1 22.9 15.7 63.5 9.5 13.1 11.2 10.4 0.1 38.1 0.4 19.2 52.5 8.2 20.4 51.0 150.0 18.3 71.8 37.4 67.2 30.6 60.9 91.1 12.5 112.6 4.7 2.9 13.7 1.4 7.8 1.3 6.4 2.6 1.3 3.9 7.4 0.9 1.5 0.3 2.1 9.8 1.6 4.0 2.5 5.0 6.9 4.4 6.5 12.1 4.5 5.0 5.9 5.4 4.5 6.3 7.8 27.8 3.2 15.1 19.6 29.1 25.5 5.1 8.3 15.9 60.3 5.4 32.4 21.9 2.8 4.2 3.7 2.1 11.8 28.8 0.5 0.0 6.8 49.0 12.5 22.4 31.4 7.7 19.8 13.6 4.8 15.5 42.9 2.6 11.3 8.2 8.6 26.0 17.7 15.2 16.8 13.6 3.0 2.0 25.1 55.2 22.4 20.2 31.5 35.6 47.8 24.0 6.8 11.3 23.6 133.2 3.6 1.4 19.5 26.4 4.7 8.3 5.7 2.4 4.6 19.7 24.0 31.7 72.2 11.1 35.0 24.0 6.0 20.6 12.2 4.7 6.5 FAM13A "ARHGAP48, FAM13A1, KIAA0914" ENSG00000138640 "Family with sequence similarity 13 member A" O94988 4 88725955-89111398 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 178.0;Oligodendrocyte precursor cells: 157.8;Syncytiotrophoblasts: 279.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 55.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038108, HPA038109" Uncertain Approved "Nucleoli,Cell Junctions,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Cell Junctions, Cytosol" Nucleoli "HPA038108: AB_2675837, HPA038109: AB_10672619" "unprognostic (1.14e-1)" "unprognostic (1.53e-2)" "unprognostic (6.29e-2)" "unprognostic (2.53e-1)" "unprognostic (3.20e-1)" "unprognostic (1.07e-1)" "unprognostic (3.79e-1)" "unprognostic (2.81e-1)" "unprognostic (8.20e-2)" "unprognostic (1.75e-1)" "unprognostic (1.46e-3)" "unprognostic (6.36e-2)" "unprognostic (4.71e-1)" "unprognostic (3.49e-3)" "unprognostic (1.90e-2)" "unprognostic (7.44e-2)" "prognostic favorable (4.28e-4)" 49.2 12.8 8.5 9.9 9.0 12.7 31.8 14.2 11.8 17.6 13.2 18.3 50.5 12.5 7.5 7.6 23.5 16.3 9.9 9.7 7.3 21.9 39.1 11.8 6.3 8.6 8.4 27.8 38.6 49.2 8.4 35.1 9.5 10.6 14.8 15.9 23.4 10.5 9.7 20.4 29.0 13.3 8.3 5.4 16.3 13.9 9.0 5.6 32.8 21.9 4.8 16.9 10.4 8.8 4.5 6.7 9.8 12.8 55.5 22.7 16.0 10.2 12.4 4.0 3.6 5.6 10.3 0.1 4.0 7.4 6.3 2.7 14.5 7.4 8.9 0.6 10.0 7.5 8.9 0.7 16.3 6.3 1.0 21.9 5.9 10.1 3.6 17.5 6.9 2.5 19.7 0.7 8.7 0.2 0.7 2.8 12.1 0.8 6.9 10.2 16.6 4.0 7.4 21.8 24.6 6.5 2.5 7.9 9.9 9.6 5.5 0.2 2.5 11.2 6.2 5.5 5.9 3.4 2.1 0.1 16.6 0.6 5.9 0.0 4.1 0.0 1.0 2.0 0.7 0.0 2.7 0.3 3.5 0.0 2.9 0.7 0.9 0.4 0.6 1.2 1.5 1.6 8.5 9.0 14.2 11.8 9.7 7.3 8.6 8.4 9.5 8.3 9.0 8.8 42.6 12.8 34.9 95.3 4.3 10.1 22.3 20.4 28.5 16.3 29.7 20.6 25.9 38.6 39.3 11.0 35.5 72.9 12.9 50.4 29.4 10.7 3.4 82.0 33.6 14.1 4.9 31.3 178.0 16.9 35.3 42.1 33.1 98.2 1.3 70.2 12.8 143.0 20.7 0.0 46.5 54.1 26.4 29.6 11.9 5.1 45.1 21.7 19.6 104.9 16.9 22.6 5.2 157.8 17.4 20.7 73.4 33.4 10.3 13.6 37.5 50.4 74.6 11.3 0.0 24.7 31.9 5.3 10.2 14.4 7.7 279.5 9.7 41.2 22.3 19.5 FAM149B1 KIAA0974 ENSG00000138286 "Family with sequence similarity 149 member B1" Q96BN6 10 73168119-73244504 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Joubert syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 41.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039189, HPA039859" Uncertain Approved Nucleoplasm NA NA "Cluster 15: NK-cells - Transcription" "Cluster 43: Testis - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA039189: AB_10805355, HPA039859: AB_2676712" "unprognostic (2.23e-1)" "unprognostic (7.04e-2)" "unprognostic (1.52e-1)" "unprognostic (4.88e-2)" "unprognostic (6.21e-2)" "unprognostic (1.45e-1)" "unprognostic (2.34e-1)" "unprognostic (4.66e-2)" "unprognostic (3.01e-1)" "unprognostic (5.25e-2)" "prognostic unfavorable (7.81e-4)" "unprognostic (5.13e-2)" "unprognostic (1.96e-3)" "unprognostic (1.22e-1)" "unprognostic (9.21e-3)" "unprognostic (2.68e-1)" "unprognostic (5.24e-2)" 12.3 10.6 20.7 6.4 23.1 5.2 12.4 22.8 22.9 14.1 18.9 9.2 7.7 11.5 12.6 11.7 13.6 12.6 12.6 19.2 21.3 21.8 19.1 10.4 9.4 21.6 22.1 15.0 12.2 13.9 6.2 13.3 22.8 10.9 9.9 11.8 11.3 10.6 13.6 7.8 8.9 11.5 21.1 8.0 9.9 21.9 21.3 12.4 12.3 17.2 9.7 10.6 7.6 25.3 8.7 8.4 19.8 19.0 45.9 28.5 13.9 12.5 28.6 9.8 17.1 2.5 23.6 8.1 5.8 25.8 10.8 10.1 12.6 18.4 11.7 11.1 4.7 6.3 5.6 7.4 23.8 10.2 6.1 24.6 13.4 12.6 48.6 44.5 24.9 11.7 5.8 15.2 18.0 10.4 7.7 12.9 8.7 29.8 19.7 4.3 11.2 9.9 26.4 12.1 3.3 20.1 11.1 30.1 19.6 17.8 18.6 9.9 12.7 8.2 6.6 8.2 12.6 20.0 8.8 4.4 15.9 11.3 7.0 0.7 0.2 0.6 0.3 0.6 0.2 0.3 0.1 0.2 0.4 0.4 0.5 0.4 0.5 1.0 0.2 0.6 0.1 0.1 20.7 23.1 22.8 22.9 19.2 21.3 21.6 22.1 22.8 21.1 21.3 25.3 5.4 3.2 3.1 24.8 3.9 2.0 3.5 4.6 6.8 6.7 5.3 5.2 12.2 5.7 5.4 1.8 6.2 7.4 2.4 4.6 1.9 3.9 21.8 6.1 7.0 6.2 7.7 3.0 19.7 3.6 5.8 7.2 5.1 6.1 2.5 8.2 7.1 4.0 5.4 3.3 24.9 5.0 6.1 6.3 3.1 27.6 8.4 4.0 1.8 12.2 4.1 4.6 1.0 23.6 41.3 4.2 2.2 4.5 1.8 4.6 6.6 6.9 9.8 11.4 13.1 5.9 5.0 13.4 5.1 5.3 3.7 8.2 3.4 7.2 5.4 4.3 FAM155B "CXorf63, TED, TMEM28" ENSG00000130054 "Family with sequence similarity 155 member B" O75949 X 69504326-69532508 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "heart muscle: 43.5" "Cell type enriched" "Detected in some" 5 "Cardiomyocytes: 23.7" "Cancer enhanced" "Detected in many" "thyroid cancer: 8.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 7.4;HAP1: 16.2;Hep G2: 6.1;NTERA-2: 24.3;OE19: 6.5;SCLC-21H: 11.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036093 Uncertain NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 5: NTERA-2 - Transcription" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA036093: AB_10673613" "prognostic unfavorable (4.61e-5)" "unprognostic (1.17e-1)" "unprognostic (2.14e-1)" "unprognostic (5.14e-3)" "unprognostic (1.45e-1)" "unprognostic (2.49e-2)" "unprognostic (3.09e-4)" "unprognostic (7.07e-2)" "unprognostic (1.19e-2)" "unprognostic (4.67e-2)" "unprognostic (4.94e-3)" "prognostic unfavorable (1.83e-4)" "prognostic favorable (6.63e-4)" "unprognostic (1.46e-2)" "unprognostic (3.50e-2)" "unprognostic (2.21e-1)" "unprognostic (8.21e-2)" 0.1 0.8 2.2 0.0 2.1 0.0 0.2 3.0 2.6 0.2 0.5 0.3 0.1 0.3 0.4 0.1 0.7 0.2 43.5 2.1 2.7 0.9 0.2 0.1 0.1 2.4 3.1 0.1 1.8 3.1 2.4 0.0 3.4 0.9 0.2 0.4 1.1 4.9 0.1 0.0 0.2 0.1 2.0 0.7 1.1 1.5 3.5 0.1 8.0 0.0 0.1 0.2 0.1 2.3 0.0 2.7 0.2 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.7 0.0 5.2 0.0 0.0 0.0 16.2 0.6 0.0 0.0 5.0 0.0 0.0 6.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 5.2 0.0 0.0 24.3 6.5 0.0 0.0 0.0 0.0 0.2 0.0 11.3 0.8 0.1 0.0 0.0 0.7 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 2.1 3.0 2.6 2.1 2.7 2.4 3.1 3.4 2.0 3.5 2.3 0.2 0.0 0.0 1.3 0.0 0.0 0.3 1.6 0.0 0.4 0.6 0.1 23.7 0.0 0.8 1.8 0.0 0.0 0.0 0.5 0.0 0.5 0.0 2.0 0.5 0.7 1.2 0.0 0.8 1.2 0.0 0.4 0.0 4.4 0.0 0.0 0.4 0.3 0.1 0.0 0.9 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.1 0.8 0.2 0.0 0.0 1.2 0.0 0.5 0.3 0.8 0.0 0.1 0.2 0.1 1.6 0.0 0.0 0.0 0.0 0.0 0.1 0.3 FAM160A1 FLJ43373 ENSG00000164142 "Family with sequence similarity 160 member A1" Q05DH4 4 151409176-151670503 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 32.3;skeletal muscle: 34.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 11.9;Excitatory neurons: 15.8;Oligodendrocyte precursor cells: 19.1;Suprabasal keratinocytes: 14.5" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 11 "cerebellum: 13.8" "Immune cell enriched" "Detected in single" 14 "plasmacytoid DC: 2.5" "Lineage enriched" "Detected in single" 14 "dendritic cells: 2.5" "Cell line enhanced" "Detected in many" "A-431: 8.6;HeLa: 10.0;hTERT-HME1: 9.2;SiHa: 8.9;SK-BR-3: 7.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" HPA046348 Enhanced Approved Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 20: HeLa - Mitochondria" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA046348: AB_10966145" "unprognostic (1.96e-1)" "unprognostic (3.40e-1)" "unprognostic (1.21e-3)" "unprognostic (2.37e-2)" "unprognostic (2.54e-2)" "unprognostic (1.38e-1)" "unprognostic (5.33e-2)" "unprognostic (4.55e-2)" "unprognostic (1.52e-1)" "unprognostic (7.21e-3)" "unprognostic (1.30e-3)" "unprognostic (2.39e-1)" "unprognostic (1.51e-12)" "unprognostic (2.41e-2)" "unprognostic (2.34e-1)" "unprognostic (2.21e-1)" "unprognostic (1.28e-1)" 0.6 1.3 0.8 0.3 0.7 1.8 4.4 13.8 1.2 3.2 32.3 3.3 1.9 1.6 4.0 7.8 2.7 0.9 3.4 1.2 0.0 3.4 0.7 1.9 0.2 0.6 0.6 2.4 10.2 8.3 1.3 0.5 0.8 2.2 3.4 6.7 4.7 1.5 34.5 13.4 2.0 1.1 0.3 0.5 2.5 3.4 0.4 1.5 6.8 16.5 2.3 2.2 3.4 0.2 8.6 0.7 0.0 0.2 0.0 0.1 2.9 0.3 1.4 0.8 0.2 3.6 3.0 0.0 0.8 0.3 2.6 7.4 2.1 6.1 0.9 0.0 3.3 0.0 10.0 0.9 0.0 0.0 0.2 0.2 7.0 0.0 9.2 2.4 0.2 0.7 0.0 0.0 0.5 1.2 0.0 0.0 2.8 2.8 0.8 0.0 2.0 0.2 5.1 5.5 1.2 0.4 8.9 7.8 0.2 2.2 3.3 0.0 0.0 0.4 3.7 0.2 1.4 0.0 0.0 0.0 1.8 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.8 0.7 13.8 1.2 1.2 0.0 0.6 0.6 0.8 0.3 0.4 0.2 0.1 3.2 2.0 1.3 0.0 11.9 6.6 2.9 10.8 0.1 2.7 1.9 1.8 0.0 5.2 0.0 0.0 0.3 0.5 5.9 0.0 1.6 3.3 5.9 0.6 0.4 0.0 0.0 15.8 1.8 0.6 0.6 6.1 10.8 1.3 0.3 0.0 0.5 0.3 8.4 2.4 2.3 0.0 0.0 2.1 1.5 0.0 0.6 0.0 1.0 0.0 2.5 0.0 19.1 1.3 1.9 0.3 0.0 1.4 7.9 2.2 0.7 1.3 4.7 0.0 1.0 0.4 6.1 5.8 11.6 14.5 1.6 0.2 0.3 1.8 8.6 FAM163B C9orf166 ENSG00000196990 "Family with sequence similarity 163 member B" P0C2L3 9 133577081-133609389 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 60.1" "Group enriched" "Detected in some" 6 "Excitatory neurons: 24.8;Inhibitory neurons: 17.8;Late spermatids: 17.3" "Cancer enriched" "Detected in some" 6 "glioma: 3.2" "Group enriched" "Detected in many" 6 "amygdala: 26.5;basal ganglia: 44.4;cerebral cortex: 60.1;hippocampal formation: 38.2;white matter: 32.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 20 "SH-SY5Y: 50.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067336 Enhanced Approved "Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear bodies, Plasma membrane, Cytosol" "HPA067336: AB_2685825" "unprognostic (2.94e-2)" "unprognostic (6.87e-3)" "unprognostic (2.65e-2)" "unprognostic (2.70e-1)" "unprognostic (1.23e-2)" "unprognostic (9.05e-2)" "unprognostic (1.02e-2)" "unprognostic (3.48e-2)" "unprognostic (1.43e-1)" "unprognostic (1.16e-1)" "unprognostic (3.31e-3)" "unprognostic (7.61e-2)" "unprognostic (5.75e-4)" "unprognostic (1.07e-1)" "unprognostic (9.54e-2)" "unprognostic (1.65e-1)" "unprognostic (4.73e-4)" 0.1 10.0 26.5 0.0 44.4 0.0 0.0 0.0 60.1 0.0 0.0 0.8 0.0 0.0 0.3 0.0 0.1 0.4 5.2 38.2 0.0 0.8 8.7 0.3 1.7 0.0 0.0 0.4 0.1 0.0 0.5 0.8 7.3 0.2 0.5 0.2 0.3 0.8 0.0 0.0 0.0 0.0 6.0 0.2 0.4 2.4 0.0 0.2 0.2 0.0 0.0 1.1 0.1 32.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 1.8 0.0 0.0 0.7 0.2 0.1 0.0 0.0 2.4 50.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.5 44.4 0.0 60.1 38.2 0.0 0.0 0.0 7.3 6.0 0.0 32.5 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 24.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.8 0.0 0.0 0.0 0.0 17.3 0.0 0.0 0.0 2.8 0.0 0.0 0.0 2.5 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FAM166A ENSG00000188163 "Family with sequence similarity 166 member A" Q6J272 9 137243584-137247770 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 31 "testis: 60.8" "Group enriched" "Detected in some" 121 "Early spermatids: 626.7;Late spermatids: 1323.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA023307 Enhanced NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 34: Spermatids - Unknown function" "HPA023307: AB_1848930" "unprognostic (2.22e-1)" "unprognostic (8.39e-2)" "unprognostic (1.01e-3)" "unprognostic (1.37e-2)" "unprognostic (1.56e-1)" "unprognostic (1.15e-1)" "unprognostic (9.83e-2)" "unprognostic (2.18e-3)" "unprognostic (1.23e-1)" "unprognostic (2.49e-1)" "unprognostic (2.67e-4)" "unprognostic (7.81e-2)" "unprognostic (1.77e-3)" "unprognostic (1.83e-1)" "unprognostic (2.02e-2)" "unprognostic (2.09e-1)" "unprognostic (4.18e-3)" 0.5 0.4 0.0 0.2 0.1 0.1 0.5 0.2 0.2 0.3 0.0 0.2 0.2 0.3 0.7 0.4 0.3 0.0 0.5 0.1 0.1 1.1 1.9 0.2 0.1 0.1 0.1 0.1 0.5 0.0 0.9 0.0 0.1 0.5 0.0 0.4 0.4 0.1 0.2 0.3 0.4 0.0 0.1 0.2 0.3 60.8 0.1 0.0 0.6 0.0 0.0 0.1 0.2 0.1 0.0 0.1 0.1 0.2 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.5 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 1.1 0.0 0.0 0.4 0.4 0.1 0.0 0.4 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 626.7 0.3 0.1 0.6 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.2 3.8 0.1 0.7 0.8 0.1 0.0 0.2 0.0 0.0 0.3 0.0 1323.3 5.9 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 6.4 0.0 0.2 0.1 0.2 1.6 0.6 0.0 0.3 0.3 8.0 4.8 0.0 0.3 0.3 0.3 0.2 0.0 0.2 FAM166C "C2orf70, LOC339778" ENSG00000173557 "Family with sequence similarity 166 member C" A6NJV1 2 26562585-26579532 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 7.6;testis: 26.6" "Cell type enhanced" "Detected in single" "Cardiomyocytes: 1.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "OE19: 21.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA062453 Enhanced Approved "Nuclear membrane,Vesicles" NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 21: OE19 - Mitochondria" "Cluster 43: Cardiomyocytes - Nuclear processes" "Nuclear membrane, Vesicles" "HPA062453: AB_2684769" "unprognostic (5.44e-2)" "unprognostic (9.30e-3)" "unprognostic (1.03e-1)" "unprognostic (4.06e-3)" "unprognostic (1.99e-2)" "unprognostic (9.40e-6)" "unprognostic (1.71e-1)" "unprognostic (4.70e-2)" "unprognostic (1.07e-1)" "prognostic favorable (6.49e-4)" "unprognostic (4.58e-2)" "unprognostic (1.52e-1)" "unprognostic (2.98e-1)" "unprognostic (2.01e-1)" "unprognostic (2.16e-3)" "unprognostic (7.08e-3)" 0.1 0.1 0.8 0.1 0.7 0.0 0.2 0.5 0.6 0.3 4.1 0.6 0.1 0.2 0.3 0.1 7.6 0.0 0.4 0.8 2.5 1.0 0.0 0.4 0.0 2.0 2.0 0.0 0.7 0.1 0.7 0.0 1.2 0.2 0.4 0.1 1.9 0.2 0.1 0.1 0.1 0.1 1.5 0.0 4.8 26.6 2.9 0.0 1.1 0.0 0.0 0.1 0.0 1.0 4.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 1.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 21.2 0.0 0.0 0.0 0.0 3.7 0.0 0.9 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.7 0.5 0.6 0.8 2.5 2.0 2.0 1.2 1.5 2.9 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FAM170B "AC084727.4, C10orf73" ENSG00000172538 "Family with sequence similarity 170 member B" A6NMN3 10 49131154-49134021 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 18 "testis: 6.4" "Cell type enriched" "Detected in some" 4 "Early spermatids: 80.7" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 20 "eosinophil: 1.9" "Lineage enriched" "Detected in single" 20 "granulocytes: 1.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043899, HPA050610" Uncertain NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 78: Testis - Spermatogenesis" "Cluster 29: Early spermatids - Spermatogenesis" "HPA043899: AB_2678721, HPA050610: AB_2681189" "unprognostic (8.01e-2)" 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 6.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.1 0.1 0.2 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 80.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 19.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FAM183A "hCG23177, LOC440585" ENSG00000186973 "Family with sequence similarity 183 member A" A6NL82 1 43145153-43156396 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "fallopian tube: 116.9" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 516.6;Late spermatids: 244.5;Respiratory ciliated cells: 1012.8" "Cancer enhanced" "Detected in many" "endometrial cancer: 19.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 3.5;hTCEpi: 2.4;NTERA-2: 3.1;SCLC-21H: 2.7;SuSa: 5.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA043382, HPA049120" Approved NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 5: NTERA-2 - Transcription" "Cluster 49: Ciliated cells - Cilium organization" "HPA043382: AB_2678456, HPA049120: AB_2680640" "unprognostic (6.66e-2)" "unprognostic (2.39e-1)" "unprognostic (9.56e-2)" "unprognostic (1.42e-3)" "unprognostic (6.79e-2)" "unprognostic (3.79e-2)" "unprognostic (1.44e-2)" "unprognostic (1.47e-1)" "unprognostic (3.94e-2)" "unprognostic (1.27e-1)" "unprognostic (5.04e-3)" "unprognostic (1.04e-1)" "unprognostic (4.30e-2)" "unprognostic (1.27e-2)" "unprognostic (7.88e-2)" "unprognostic (1.18e-3)" "unprognostic (1.73e-2)" 0.0 0.0 1.3 0.0 1.2 0.0 1.0 0.5 0.3 2.5 9.2 0.2 0.1 2.1 0.5 1.0 116.9 0.0 0.0 1.2 2.1 1.3 0.1 6.9 0.0 8.1 7.2 0.2 0.2 0.9 5.5 0.6 3.9 2.0 0.3 0.2 1.4 0.2 0.0 9.7 0.0 0.2 4.2 0.0 0.1 6.9 1.4 0.3 0.0 0.0 0.3 0.5 1.1 2.3 0.3 0.0 0.8 0.0 0.0 0.0 0.2 0.0 0.3 0.3 0.3 0.6 3.5 0.0 0.4 0.2 0.3 0.4 0.0 0.2 0.2 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 3.1 0.1 0.0 0.0 0.0 0.0 1.4 0.6 2.7 0.0 0.0 0.1 0.0 5.2 0.7 0.0 0.5 0.0 0.3 0.1 0.0 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.2 0.5 0.3 1.2 2.1 8.1 7.2 3.9 4.2 1.4 2.3 0.0 0.0 7.4 0.0 0.0 1.9 14.0 66.1 3.4 0.0 1.4 2.3 0.2 0.0 109.2 3.7 0.0 2.1 0.1 0.4 3.9 0.0 107.7 516.6 3.5 1.3 4.2 0.0 0.0 0.0 0.2 1.2 0.0 5.7 3.8 0.1 0.0 0.0 0.1 0.0 0.0 0.4 54.9 0.0 0.0 244.5 1.8 0.7 3.6 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.2 0.7 0.0 3.9 0.0 2.0 1012.8 0.1 0.0 0.0 13.3 7.6 3.5 2.3 2.6 2.1 0.6 0.2 0.5 9.7 FAM205C FAM205CP ENSG00000187791 "Family with sequence similarity 205 member C" A6NFA0 9 34889066-34895764 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 38 "testis: 28.9" "Group enriched" "Detected in some" 91 "Early spermatids: 275.6;Late spermatids: 489.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 103 "THP-1: 14.8" "Not detected" "Not detected" NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 43: THP-1 - Innate immune response" "Cluster 34: Spermatids - Unknown function" "unprognostic (1.29e-1)" "unprognostic (1.90e-1)" "unprognostic (3.64e-2)" "unprognostic (8.64e-2)" "unprognostic (2.63e-1)" "unprognostic (1.84e-1)" "unprognostic (7.73e-2)" "unprognostic (1.85e-4)" "unprognostic (1.48e-3)" 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.7 0.1 0.1 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.3 0.3 0.1 0.0 0.0 0.1 0.1 28.9 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.2 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 4.2 0.0 0.0 0.0 1.9 0.0 275.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 489.3 1.2 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 2.6 0.0 0.5 0.0 0.0 0.0 2.7 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FAM241B C10orf35 ENSG00000171224 "Family with sequence similarity 241 member B" Q96D05 10 69630247-69633596 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 40.3" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 19.4;Collecting duct cells: 16.5;Distal tubular cells: 11.7;Ductal cells: 24.3;Exocrine glandular cells: 18.4;Pancreatic endocrine cells: 20.7;Proximal tubular cells: 13.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 13 "gdT-cell: 4.3;MAIT T-cell: 10.9;memory CD4 T-cell: 10.5;memory CD8 T-cell: 7.0;naive CD4 T-cell: 17.2;naive CD8 T-cell: 5.7;T-reg: 7.8" "Lineage enriched" "Detected in single" 25 "T-cells: 17.2" "Cell line enhanced" "Detected in many" "PC-3: 57.5" "Low region specificity" "Detected in all" HPA034591 Enhanced Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 1: Pancreatic cells - Digestion" "Nucleoplasm, Centrosome" Cytosol "HPA034591: AB_10670572" "unprognostic (1.12e-1)" "unprognostic (6.37e-2)" "unprognostic (3.13e-2)" "unprognostic (1.17e-1)" "unprognostic (7.17e-3)" "prognostic unfavorable (8.64e-4)" "prognostic unfavorable (1.03e-4)" "unprognostic (3.56e-2)" "unprognostic (1.73e-1)" "unprognostic (2.12e-1)" "unprognostic (1.99e-2)" "unprognostic (1.63e-1)" "unprognostic (3.37e-2)" "unprognostic (3.12e-2)" "unprognostic (5.23e-2)" "unprognostic (2.52e-1)" "prognostic favorable (9.72e-4)" 1.6 3.0 26.3 1.9 27.3 1.1 4.7 30.4 40.3 2.2 19.2 6.6 2.7 3.2 11.1 4.8 4.3 2.0 6.6 35.5 31.7 10.7 3.7 4.0 2.9 21.7 24.2 2.1 8.2 8.2 12.7 1.2 28.2 7.8 2.3 11.3 5.5 4.7 4.7 3.4 3.5 3.8 21.5 1.4 5.8 22.2 26.4 2.8 5.8 1.2 2.3 5.8 3.0 22.2 29.4 31.9 3.9 31.8 0.0 0.0 13.6 2.9 0.8 5.1 5.6 23.4 23.6 0.0 42.8 0.6 18.6 11.8 16.6 9.6 7.1 29.4 22.8 0.0 6.7 8.8 8.1 0.0 10.0 0.0 9.4 0.2 4.8 3.8 0.0 43.8 11.1 0.1 0.5 39.9 0.3 0.0 19.1 11.8 57.5 0.0 0.0 0.4 10.9 16.6 16.0 22.2 12.1 29.6 19.0 7.8 20.5 5.1 1.4 0.8 19.4 0.1 8.5 5.1 15.2 0.1 0.4 0.0 0.8 0.0 0.0 0.0 4.3 0.0 10.9 0.1 10.5 7.0 0.1 0.4 17.2 5.7 0.6 0.2 0.0 0.1 7.8 3.1 26.3 27.3 30.4 40.3 35.5 31.7 21.7 24.2 28.2 21.5 26.4 22.2 1.4 0.0 4.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 8.3 19.4 0.0 0.0 3.1 16.5 0.0 7.5 0.6 0.0 11.7 24.3 0.0 5.7 0.4 0.7 0.0 0.0 0.0 18.4 5.6 0.6 0.0 5.0 0.0 8.6 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 2.0 0.0 0.0 0.0 0.0 20.7 0.0 0.0 0.3 0.0 0.0 13.5 4.4 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 1.9 2.8 3.7 0.0 0.0 FAM3B "2-21, C21orf11, C21orf76, D21M16SJHU19e, ORF9, PANDER, PRED44" ENSG00000183844 "FAM3 metabolism regulating signaling molecule B" P58499 21 41304212-41357727 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Apoptosis Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 142.6;pancreas: 212.3;salivary gland: 119.4;stomach 1: 114.9" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 304.6;Exocrine glandular cells: 399.9;Proximal enterocytes: 831.6" "Cancer enhanced" "Detected in many" "prostate cancer: 40.3" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "eosinophil: 1.4;neutrophil: 2.8" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.8" "Cell line enhanced" "Detected in some" "CACO-2: 19.5;CAPAN-2: 11.7;Hep G2: 32.1;OE19: 27.3;RPMI-8226: 80.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA015885, HPA029777, CAB034131" Enhanced Approved Vesicles "Secreted to blood" NA NA 2080000 250000 "Cluster 1: Neutrophils - Mixed function" "Cluster 25: Pancreas - Digestion" "Cluster 25: RPMI-8226 - Immune response" "Cluster 45: Enterocytes - Digestion" Vesicles "CAB034131: AB_2231472, HPA015885: AB_1848396, HPA029777: AB_2673194" "unprognostic (2.88e-1)" "unprognostic (3.31e-3)" "unprognostic (5.13e-2)" "unprognostic (1.27e-1)" "unprognostic (2.62e-1)" "unprognostic (6.32e-3)" "unprognostic (1.41e-1)" "unprognostic (8.79e-3)" "unprognostic (9.38e-2)" "unprognostic (1.70e-1)" "unprognostic (4.65e-1)" "unprognostic (3.78e-1)" "unprognostic (5.60e-3)" "unprognostic (1.57e-1)" "unprognostic (1.80e-1)" "unprognostic (1.78e-1)" "unprognostic (1.55e-3)" 1.5 0.1 0.0 2.5 0.1 0.8 17.7 0.1 0.3 4.9 1.3 5.9 142.6 0.3 22.1 56.2 17.2 16.2 0.6 0.1 0.1 17.9 2.6 9.3 1.5 0.1 0.1 0.2 212.3 0.5 5.4 15.2 0.1 37.9 0.1 0.0 119.4 8.7 0.1 2.3 135.0 0.5 0.1 0.6 114.9 6.9 0.1 3.1 8.0 0.0 16.8 34.4 16.8 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 19.5 11.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 32.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.4 0.9 27.3 0.0 0.2 0.0 80.6 0.0 5.8 0.4 0.4 0.0 0.7 0.4 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.2 0.0 0.3 1.4 0.0 0.1 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 2.8 0.0 0.3 0.7 0.0 0.0 0.0 0.1 0.1 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 1.0 22.4 25.7 0.0 0.8 1.3 17.0 2.9 1.2 0.0 101.3 123.1 0.2 102.9 36.5 66.2 0.0 304.6 1.4 2.7 25.4 172.1 25.2 0.2 0.1 2.5 0.0 0.0 0.1 399.9 11.1 3.4 147.3 0.7 1.3 0.6 0.4 0.3 27.0 0.0 0.1 120.9 42.7 5.0 15.8 11.5 0.6 3.9 5.4 1.9 2.1 0.0 0.0 0.0 0.1 144.6 169.0 0.4 0.2 64.9 831.6 0.7 22.4 0.0 0.0 0.4 1.8 28.0 8.1 29.1 1.3 161.3 0.9 0.0 125.2 130.5 FAM71A FLJ32796 ENSG00000162771 "Family with sequence similarity 71 member A" Q8IYT1 1 212624474-212626775 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 105 "testis: 78.7" "Group enriched" "Detected in many" 50 "Early spermatids: 1174.2;Late spermatids: 453.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA028462, HPA060344" Enhanced Approved "Nuclear speckles" NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 29: Early spermatids - Spermatogenesis" "Nuclear speckles" "HPA028462: AB_10601904, HPA060344: " 0.4 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.3 0.0 0.0 0.1 78.7 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 3.8 0.0 3.7 0.0 0.1 0.5 1.7 4.4 0.6 0.1 3.5 6.7 0.0 4.3 3.3 0.0 0.0 2.6 0.3 1.9 0.0 0.7 1174.2 7.2 2.8 1.6 1.2 0.0 0.0 1.2 1.5 1.8 9.7 16.0 1.3 0.0 1.8 0.4 1.2 0.0 0.0 2.8 0.0 0.0 0.3 453.8 5.3 2.7 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.9 2.8 2.6 0.6 2.5 0.4 0.0 1.5 0.0 0.0 3.2 2.7 3.9 2.4 0.8 0.1 2.9 0.8 0.1 2.0 0.5 FAM71B MGC26988 ENSG00000170613 "Family with sequence similarity 71 member B" Q8TC56 5 157161846-157166264 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 316 "testis: 31.6" "Group enriched" "Detected in some" 167 "Early spermatids: 871.3;Late spermatids: 401.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA039478, HPA040771" Enhanced NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 29: Early spermatids - Spermatogenesis" "HPA039478: AB_10795106, HPA040771: AB_10805829" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 871.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 401.4 3.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FAM71E2 "C19orf16, DKFZp434G1729" ENSG00000180043 "Family with sequence similarity 71 member E2" Q8N5Q1 19 55354908-55363260 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 152 "testis: 28.5" "Group enriched" "Detected in some" 18 "Early spermatids: 4.1;Late spermatids: 10.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (5.97e-2)" "unprognostic (2.27e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FAM71F1 "FAM137A, NYD-SP18" ENSG00000135248 "Family with sequence similarity 71 member F1" Q96KD3 7 128709061-128731743 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 88 "testis: 93.9" "Group enriched" "Detected in some" 93 "Early spermatids: 1122.8;Late spermatids: 2008.1" "Cancer enriched" "Detected in single" 23 "testis cancer: 4.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 11 "NTERA-2: 16.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA020636 Uncertain Cytosol No NA "Cluster 74: Testis - Spermatogenesis" "Cluster 5: NTERA-2 - Transcription" "Cluster 34: Spermatids - Unknown function" Cytosol "HPA020636: AB_1854739" "unprognostic (3.09e-2)" "unprognostic (3.39e-3)" "unprognostic (6.03e-2)" "unprognostic (5.25e-1)" "unprognostic (2.97e-1)" "unprognostic (1.20e-1)" "unprognostic (4.67e-2)" "unprognostic (2.17e-1)" "unprognostic (1.95e-2)" "unprognostic (1.00e-5)" "unprognostic (1.48e-1)" "unprognostic (2.18e-6)" "unprognostic (6.97e-2)" "unprognostic (2.09e-1)" "unprognostic (2.19e-3)" "unprognostic (1.99e-1)" 0.0 0.0 0.8 0.0 0.7 0.0 0.1 0.4 0.9 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.7 0.6 0.4 0.0 0.1 0.0 0.6 1.0 0.0 0.1 0.0 0.5 0.0 0.8 0.2 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.1 0.0 93.9 1.0 0.0 0.1 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 16.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.2 1.4 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.7 0.4 0.9 0.7 0.6 0.6 1.0 0.8 0.5 1.0 0.6 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.1 0.3 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.1 1122.8 0.2 0.1 0.6 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1.0 0.0 2008.1 12.8 0.7 0.0 0.0 0.0 0.3 0.0 0.5 0.4 0.0 0.0 10.9 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.8 0.1 16.7 6.8 0.0 0.1 1.2 0.0 0.5 0.0 0.0 FAM83C "C20orf128, dJ614O4.7" ENSG00000125998 "Family with sequence similarity 83 member C" Q9BQN1 20 35285731-35292425 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "esophagus: 33.3;skin 1: 42.3;vagina: 15.0" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 27.9;Basal squamous epithelial cells: 17.6;Early spermatids: 11.8;Squamous epithelial cells: 26.1;Suprabasal keratinocytes: 64.2" "Cancer enhanced" "Detected in some" "cervical cancer: 9.9;head and neck cancer: 18.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB034227, HPA049978" Uncertain NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "CAB034227: AB_1562876, HPA049978: AB_2680979" "unprognostic (3.76e-2)" "unprognostic (2.88e-1)" "unprognostic (1.02e-1)" "unprognostic (1.28e-3)" "unprognostic (1.09e-1)" "unprognostic (2.61e-1)" "unprognostic (3.61e-1)" "unprognostic (1.57e-1)" "unprognostic (4.38e-2)" "unprognostic (3.11e-1)" "unprognostic (9.17e-5)" "unprognostic (9.89e-3)" "unprognostic (1.71e-1)" "unprognostic (5.01e-2)" 0.0 0.0 0.1 0.0 0.1 0.0 0.9 0.0 0.2 5.3 0.0 0.0 0.0 0.0 0.0 33.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 4.2 0.0 0.1 42.3 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 2.1 0.6 15.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 27.9 1.1 0.0 17.6 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 11.8 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 1.2 6.5 0.3 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.2 0.3 1.3 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 26.1 64.2 0.0 0.0 0.0 0.1 1.9 FAM83G "FLJ41564, PAWS1" ENSG00000188522 "Family with sequence similarity 83 member G" A6ND36 17 18968789-19004764 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 51.3;skin 1: 67.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 77.8;Basal squamous epithelial cells: 39.3;Distal enterocytes: 46.5;Squamous epithelial cells: 55.3;Suprabasal keratinocytes: 68.5" "Cancer enhanced" "Detected in many" "head and neck cancer: 22.2" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA023369, HPA023940" Enhanced Approved Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol "HPA023369: AB_1848415, HPA023940: AB_1848416" "unprognostic (2.12e-2)" "unprognostic (5.90e-2)" "unprognostic (1.17e-1)" "unprognostic (9.48e-2)" "unprognostic (1.42e-3)" "unprognostic (2.04e-2)" "prognostic unfavorable (8.29e-4)" "unprognostic (1.07e-3)" "unprognostic (1.14e-1)" "unprognostic (2.03e-2)" "unprognostic (1.17e-1)" "unprognostic (3.51e-2)" "unprognostic (5.65e-2)" "prognostic favorable (7.58e-6)" "unprognostic (9.68e-2)" "unprognostic (5.13e-2)" "unprognostic (3.74e-2)" 2.3 2.2 0.8 2.9 0.8 1.4 2.8 0.8 1.2 10.8 2.1 8.2 10.8 2.5 0.9 51.3 1.6 6.4 17.2 0.8 1.9 7.1 21.7 3.2 3.0 1.6 1.4 1.4 9.5 6.4 4.3 0.7 2.7 3.5 5.3 0.2 10.9 2.2 6.9 67.3 11.3 1.5 0.9 2.0 9.8 1.0 1.4 3.7 5.6 0.8 5.7 2.5 17.0 0.7 24.7 22.4 0.2 0.0 0.7 2.0 35.9 25.2 11.0 21.0 15.7 28.7 8.8 16.1 15.1 16.7 17.1 28.6 3.6 21.1 9.6 13.2 8.1 0.4 11.2 15.9 15.3 2.9 7.9 2.8 38.9 13.6 22.3 7.9 7.6 2.5 7.7 0.5 6.0 15.0 0.7 6.0 11.0 34.1 0.1 0.1 0.0 7.8 10.1 6.2 11.2 0.0 8.7 5.3 1.5 29.1 9.2 3.6 14.2 12.9 21.6 6.1 29.8 2.2 4.0 4.1 10.1 0.1 8.6 1.1 0.0 0.0 0.7 0.0 0.3 0.3 0.4 0.2 0.0 0.3 0.3 0.0 0.0 0.0 0.2 0.0 0.5 0.2 0.8 0.8 0.8 1.2 0.8 1.9 1.6 1.4 2.7 0.9 1.4 0.7 0.6 3.2 2.2 0.0 2.5 77.8 12.2 9.9 39.3 0.2 7.1 2.9 5.1 11.5 6.3 7.3 0.0 0.4 0.7 46.5 0.0 15.8 0.1 2.4 1.0 1.9 7.1 2.7 0.1 10.0 9.7 2.6 17.3 5.0 8.9 3.5 1.1 20.9 1.2 0.0 0.1 17.7 8.2 0.3 7.8 1.9 0.0 1.0 5.4 0.0 1.0 0.2 3.1 0.5 0.0 24.3 22.8 0.0 3.0 13.2 15.3 4.4 2.5 0.4 0.0 1.3 2.0 0.1 1.0 55.3 68.5 1.9 2.6 0.0 17.1 9.1 FAM89A "C1orf153, MGC15887" ENSG00000182118 "Family with sequence similarity 89 member A" Q96GI7 1 231018958-231040254 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 60.0;placenta: 68.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 186.3;Extravillous trophoblasts: 267.5;Rod photoreceptor cells: 102.5;Syncytiotrophoblasts: 278.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.4" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BEWO: 145.4;SK-MEL-30: 81.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA059052, HPA059578" Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Golgi apparatus, Vesicles" Nucleoplasm "HPA059052: AB_2683890, HPA059578: AB_2684070" "unprognostic (7.80e-2)" "unprognostic (1.20e-1)" "unprognostic (3.58e-3)" "unprognostic (1.32e-2)" "unprognostic (2.77e-1)" "unprognostic (1.41e-2)" "unprognostic (1.98e-2)" "unprognostic (1.10e-1)" "unprognostic (8.05e-3)" "unprognostic (4.85e-1)" "unprognostic (1.54e-1)" "unprognostic (6.44e-2)" "prognostic unfavorable (1.75e-5)" "unprognostic (2.87e-2)" "unprognostic (2.03e-1)" "unprognostic (2.01e-1)" "unprognostic (9.26e-2)" 60.0 18.0 16.0 4.8 15.3 5.9 36.5 20.7 16.4 11.0 21.3 4.4 1.7 7.5 1.6 6.5 7.1 5.9 10.6 14.2 23.4 22.2 9.2 19.2 5.9 22.6 21.4 6.0 10.6 6.0 5.8 68.2 20.9 7.1 2.7 17.3 5.3 4.6 5.9 30.6 4.6 4.1 21.2 17.5 7.6 3.0 25.1 2.9 5.5 6.7 4.7 8.9 9.2 19.5 0.9 13.7 6.3 13.4 15.0 3.0 145.4 7.8 5.8 2.8 5.1 21.1 12.1 0.0 1.8 5.1 16.7 8.4 12.0 1.9 2.3 42.4 28.9 6.7 0.3 0.9 57.6 5.0 35.2 50.1 26.6 0.0 13.2 0.1 7.4 15.0 53.4 8.6 2.7 5.0 3.2 8.8 9.4 12.6 4.3 16.6 20.3 16.0 10.1 14.8 5.8 16.1 2.6 1.2 81.6 13.9 0.8 29.2 1.1 22.5 0.1 0.4 14.7 18.3 23.7 11.6 6.7 9.8 45.7 1.4 0.2 0.0 0.2 0.0 0.3 0.3 0.2 0.5 0.0 0.1 0.4 0.9 0.0 0.1 0.0 0.0 0.0 0.2 16.0 15.3 20.7 16.4 14.2 23.4 22.6 21.4 20.9 21.2 25.1 19.5 82.3 0.0 2.6 3.6 4.2 30.1 22.0 0.3 8.0 48.1 3.8 5.2 3.3 7.2 0.7 0.0 77.2 186.3 4.9 0.3 3.9 2.8 1.3 1.3 39.3 44.5 0.0 14.9 1.1 3.3 267.5 11.6 0.5 2.6 4.5 0.5 10.8 11.1 51.0 8.4 10.8 0.6 0.0 19.6 2.1 3.6 2.8 8.5 21.4 22.5 0.5 26.2 1.0 10.1 2.0 4.4 0.5 1.5 1.4 30.2 0.0 5.1 0.1 102.5 0.0 9.9 8.5 4.2 11.6 1.7 32.8 278.3 5.5 0.4 1.3 15.4 FAM98A DKFZP564F0522 ENSG00000119812 "Family with sequence similarity 98 member A" Q8NCA5 2 33583660-33599382 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036250, HPA036251" Uncertain Approved Vesicles NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 52: Non-specific - Transcription" Vesicles "HPA036250: AB_2675020, HPA036251: AB_10673124" "unprognostic (7.25e-2)" "unprognostic (9.92e-2)" "unprognostic (1.59e-2)" "unprognostic (1.40e-1)" "unprognostic (1.51e-1)" "unprognostic (2.42e-2)" "prognostic unfavorable (4.86e-7)" "unprognostic (1.07e-1)" "unprognostic (2.29e-1)" "unprognostic (2.78e-2)" "unprognostic (1.01e-1)" "unprognostic (3.51e-1)" "unprognostic (2.02e-2)" "unprognostic (2.38e-2)" "unprognostic (2.66e-1)" "prognostic unfavorable (8.18e-5)" "unprognostic (6.01e-2)" 29.2 21.5 21.4 20.5 26.5 7.2 16.3 28.6 30.4 21.7 27.9 20.7 13.6 19.1 19.3 19.9 12.2 15.7 40.6 30.8 25.7 27.4 25.5 11.5 18.4 25.1 24.5 16.5 14.6 51.2 20.5 20.6 29.5 23.0 17.1 17.2 28.0 16.7 61.3 14.9 12.1 36.4 27.7 14.3 19.8 49.4 26.4 17.4 19.2 62.4 22.6 27.5 12.9 39.7 93.4 47.2 25.5 43.9 99.4 108.3 41.9 224.1 81.6 62.3 80.2 49.8 18.8 144.5 41.3 101.8 55.3 41.3 84.8 60.8 84.2 67.7 56.3 119.7 46.9 69.3 47.2 95.5 44.7 56.1 42.2 83.9 52.1 63.5 83.3 15.5 84.4 43.8 108.7 46.1 53.3 28.5 64.4 83.2 59.9 41.1 82.5 51.9 65.0 72.2 45.6 26.1 60.0 89.5 27.0 40.7 36.2 15.6 135.7 39.5 66.1 82.9 89.2 80.2 106.6 142.4 91.2 68.2 56.8 1.3 4.1 2.3 6.4 7.2 6.9 10.7 5.4 5.8 6.1 5.5 6.9 5.7 0.1 4.0 4.6 3.5 9.0 4.1 21.4 26.5 28.6 30.4 30.8 25.7 25.1 24.5 29.5 27.7 26.4 39.7 19.0 22.4 11.5 6.8 17.4 20.4 19.0 12.2 18.8 16.8 15.0 14.0 74.6 11.5 19.8 7.3 2.1 25.5 9.8 6.9 25.4 20.3 14.9 16.7 29.9 21.1 5.4 12.8 22.8 29.2 33.2 31.9 17.9 18.9 2.5 44.4 17.2 23.4 16.4 47.1 15.7 15.1 8.2 7.7 11.8 13.8 22.4 8.7 8.8 6.5 5.9 17.4 16.5 9.0 36.1 26.0 8.7 21.8 40.3 22.6 9.3 46.2 16.5 15.7 0.0 21.7 27.1 41.5 40.1 26.1 20.5 40.0 13.7 54.9 12.1 23.4 FANCD2OS "C3orf24, MGC40179" ENSG00000163705 "FANCD2 opposite strand" Q96PS1 3 10081317-10108255 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 33 "testis: 61.6" "Group enriched" "Detected in some" 59 "Early spermatids: 565.0;Late spermatids: 852.8" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "cerebellum: 1.8" "Immune cell enriched" "Detected in some" 5 "neutrophil: 5.4" "Lineage enriched" "Detected in many" 5 "granulocytes: 5.4" "Cell line enhanced" "Detected in some" "CACO-2: 1.3;MCF7: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA076166 Approved Vesicles NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 74: Testis - Spermatogenesis" "Cluster 39: CACO-2 - Unknown function" "Cluster 34: Spermatids - Unknown function" Vesicles "HPA076166: " "unprognostic (5.99e-2)" "unprognostic (4.33e-3)" "unprognostic (8.04e-2)" "unprognostic (1.11e-3)" "unprognostic (3.51e-1)" "unprognostic (2.63e-2)" "unprognostic (4.78e-2)" "unprognostic (3.49e-1)" "unprognostic (2.53e-3)" "unprognostic (3.91e-2)" "unprognostic (9.45e-2)" "unprognostic (2.11e-7)" "unprognostic (2.95e-1)" "unprognostic (1.23e-1)" "unprognostic (2.15e-1)" "unprognostic (1.80e-1)" 0.0 0.0 0.3 0.0 0.1 1.0 0.0 1.8 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.2 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.0 61.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.4 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.1 0.0 0.2 0.5 0.4 0.3 0.2 0.4 0.3 0.3 0.4 0.2 0.1 0.8 0.3 0.3 5.4 0.2 1.0 0.3 0.1 0.1 0.3 0.1 1.8 0.4 0.2 0.1 0.3 0.2 0.3 0.1 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 565.0 0.4 0.0 0.3 0.0 0.0 0.7 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 852.8 7.2 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.9 0.0 4.1 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 12.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FAR2 "FLJ10462, MLSTD1, SDR10E2" ENSG00000064763 "Fatty acyl-CoA reductase 2" Q96K12 12 29149103-29340980 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 36.2;intestine: 34.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 114.3;Inhibitory neurons: 172.1;Microglial cells: 63.7;Syncytiotrophoblasts: 193.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 50.0" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 76.2;HUVEC TERT2: 84.0;NB-4: 74.2;SK-BR-3: 89.6;TIME: 68.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015884 Approved Approved "Nucleoli,Golgi apparatus" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 37: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" Nucleoli "HPA015884: AB_1853998" "unprognostic (6.32e-2)" "unprognostic (2.40e-2)" "unprognostic (1.50e-3)" "unprognostic (3.33e-3)" "unprognostic (2.41e-1)" "unprognostic (4.13e-3)" "unprognostic (4.30e-2)" "unprognostic (1.18e-1)" "unprognostic (3.11e-2)" "unprognostic (6.37e-2)" "unprognostic (5.70e-3)" "unprognostic (1.92e-1)" "prognostic unfavorable (4.93e-4)" "unprognostic (2.10e-1)" "unprognostic (2.23e-1)" "unprognostic (1.33e-1)" "unprognostic (5.22e-3)" 8.3 9.0 4.1 9.3 8.3 17.1 9.3 1.2 8.5 4.3 0.0 34.5 17.6 5.6 36.2 7.4 3.6 5.2 6.6 6.2 9.2 5.0 3.8 11.3 7.9 1.2 2.9 2.3 3.2 1.3 2.4 18.1 1.3 2.6 28.2 9.4 4.4 1.9 6.3 9.0 19.2 7.6 1.4 12.2 4.9 9.2 5.2 7.0 4.4 2.6 3.0 6.5 3.7 4.9 2.5 4.9 4.9 1.2 6.8 26.9 2.1 21.3 24.7 5.8 5.4 8.2 28.0 3.7 5.4 3.4 4.3 1.5 13.4 0.2 1.4 1.8 32.2 76.2 10.7 2.7 14.7 30.0 24.0 7.5 0.2 8.7 11.0 14.3 84.0 2.9 6.6 2.7 0.9 0.8 19.9 74.2 19.3 1.6 54.5 16.1 7.9 3.1 25.7 7.2 8.6 7.9 4.8 89.6 37.8 9.7 4.1 28.2 68.2 15.6 4.6 5.6 9.3 4.4 4.9 1.8 24.5 38.5 13.7 3.8 22.8 50.0 5.0 13.9 3.4 2.0 8.3 6.2 8.1 1.8 2.9 3.2 41.0 4.0 8.0 3.1 16.1 9.6 4.1 8.3 1.2 8.5 6.2 9.2 1.2 2.9 1.3 1.4 5.2 4.9 9.1 0.0 3.3 7.8 0.6 1.3 0.1 0.2 0.6 2.0 1.4 0.8 12.1 0.0 1.4 0.0 0.0 16.0 1.1 35.7 0.0 0.1 31.5 0.4 2.9 11.9 7.2 4.6 114.3 0.2 19.6 4.8 5.6 0.4 10.8 0.0 9.7 0.0 19.3 5.0 172.1 21.8 0.0 22.2 3.7 6.4 1.2 12.2 16.0 63.7 6.9 0.5 1.0 24.6 6.9 3.3 36.8 0.4 8.0 0.4 15.1 0.4 3.2 1.2 0.0 4.2 3.6 16.6 1.0 0.3 0.3 193.9 4.2 0.9 23.7 0.3 FARP2 "FIR, FRG, KIAA0793, PLEKHC3" ENSG00000006607 "FERM, ARH/RhoGEF and pleckstrin domain protein 2" O94887 2 241356285-241494841 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 128.2;Oligodendrocytes: 114.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031226, HPA055592" Approved Approved Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 68: Oligodendrocytes - Mixed function" Cytosol "HPA031226: AB_10602808, HPA055592: AB_2682856" "unprognostic (3.07e-1)" "unprognostic (1.39e-1)" "unprognostic (3.75e-2)" "unprognostic (1.07e-2)" "unprognostic (2.51e-1)" "unprognostic (1.37e-2)" "unprognostic (1.60e-2)" "unprognostic (1.70e-1)" "unprognostic (1.83e-1)" "unprognostic (2.19e-1)" "unprognostic (1.71e-1)" "unprognostic (1.90e-1)" "unprognostic (9.11e-2)" "unprognostic (6.31e-2)" "unprognostic (6.78e-2)" "unprognostic (2.74e-1)" "unprognostic (1.73e-1)" 9.6 10.3 13.8 11.4 16.8 5.4 9.0 19.3 16.0 10.0 9.8 22.6 20.2 10.6 7.3 14.1 9.2 10.0 7.6 13.2 12.9 11.0 17.1 10.4 11.9 15.6 15.2 11.0 11.4 13.2 8.4 9.0 15.6 10.1 21.3 10.1 9.2 10.0 10.6 22.6 18.9 11.6 11.7 11.6 20.3 28.1 16.2 8.5 6.8 9.9 13.8 14.2 10.1 21.3 20.0 14.3 25.8 17.7 21.9 29.1 23.1 19.7 16.3 20.0 20.6 15.3 23.4 8.5 5.2 38.8 14.1 22.4 35.0 20.6 30.4 13.3 18.1 18.8 25.4 20.3 16.0 17.0 14.1 29.3 15.2 29.2 23.7 9.3 18.4 16.1 21.7 7.6 16.3 16.7 18.3 12.5 12.8 35.3 11.1 20.3 58.2 25.7 25.9 41.0 30.5 20.3 22.1 15.4 59.5 14.9 8.1 16.8 27.9 18.8 14.3 23.8 16.0 13.0 10.0 18.8 17.2 11.5 39.0 6.1 2.1 7.3 1.3 5.1 1.2 4.4 1.4 1.5 3.1 4.9 0.9 1.0 1.3 1.7 2.8 6.4 2.2 1.6 13.8 16.8 19.3 16.0 13.2 12.9 15.6 15.2 15.6 11.7 16.2 21.3 8.9 28.9 5.9 27.4 23.9 15.4 11.4 8.0 16.5 12.7 11.1 8.3 29.6 14.3 12.3 18.4 18.8 5.8 9.7 36.3 3.9 9.3 42.7 12.0 10.6 10.5 28.1 3.4 43.1 12.3 5.4 12.9 45.3 14.0 6.3 15.9 11.0 11.6 4.2 20.2 36.7 38.7 10.2 8.4 9.4 25.0 14.9 11.9 39.2 38.4 8.5 4.9 2.1 128.2 114.0 12.6 24.1 10.5 14.4 12.8 20.9 7.1 17.3 15.1 19.7 21.4 14.1 45.6 19.7 13.8 15.2 11.1 6.0 11.3 26.2 22.4 FAT2 "CDHF8, CDHR9, HFAT2, MEGF1" ENSG00000086570 "FAT atypical cadherin 2" Q9NYQ8 5 151504093-151568944 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 113.4;esophagus: 50.9;skin 1: 56.0" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 18.0;Basal respiratory cells: 31.6;Basal squamous epithelial cells: 27.9;Early spermatids: 16.0;Extravillous trophoblasts: 20.6;Squamous epithelial cells: 53.2;Suprabasal keratinocytes: 19.6" "Group enriched" "Detected in many" 6 "cervical cancer: 13.9;head and neck cancer: 21.4;lung cancer: 6.1;urothelial cancer: 5.6" "Region enriched" "Detected in many" 7 "cerebellum: 113.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "BEWO: 35.1;EFO-21: 21.0;HaCaT: 51.7;HBEC3-KT: 23.6;hTCEpi: 70.5" "Region enriched" "Detected in some" 18 "cerebellum: 32.0" "Region enriched" "Detected in many" 56 "cerebellum: 224.4" CAB033680 Enhanced NA NA 300000 "Cluster 27: Brain & Skin - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "CAB033680: AB_2100956" "unprognostic (8.06e-3)" "unprognostic (6.01e-2)" "unprognostic (3.47e-1)" "unprognostic (4.80e-3)" "unprognostic (1.33e-1)" "unprognostic (4.43e-1)" "unprognostic (9.78e-3)" "unprognostic (2.28e-1)" "unprognostic (8.25e-2)" "unprognostic (2.65e-1)" "unprognostic (2.96e-2)" "unprognostic (1.90e-1)" "unprognostic (1.84e-7)" "unprognostic (2.38e-1)" "unprognostic (1.47e-1)" "unprognostic (6.77e-2)" "unprognostic (3.64e-3)" 0.4 0.2 0.4 0.0 3.8 0.1 3.6 113.4 4.8 11.5 0.0 0.1 0.1 0.1 1.7 50.9 1.0 0.0 0.1 0.5 0.4 0.6 0.1 0.2 0.0 15.1 2.8 0.1 0.2 0.2 0.5 0.9 17.2 5.3 0.0 0.1 8.9 4.8 0.2 56.0 0.2 0.0 0.4 0.1 0.1 13.2 0.5 2.2 0.1 0.0 3.4 2.9 24.4 2.2 1.7 0.0 0.0 0.1 0.0 0.0 35.1 0.2 0.0 0.0 0.0 0.1 0.0 0.1 21.0 0.0 0.2 51.7 0.0 23.6 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.1 0.0 70.5 0.0 3.8 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.7 0.1 0.0 0.1 1.1 0.2 0.5 0.0 0.0 0.1 0.1 0.4 0.0 0.1 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 3.8 113.4 4.8 0.5 0.4 15.1 2.8 17.2 0.4 0.5 2.2 0.1 0.0 0.0 0.7 0.0 18.0 5.8 31.6 27.9 0.0 3.4 12.8 1.9 0.0 11.1 1.8 0.0 0.4 0.0 0.0 0.0 0.0 16.0 0.1 0.0 0.3 0.0 0.0 5.0 0.0 20.6 0.3 0.0 0.7 0.0 0.0 0.0 0.0 0.8 0.0 2.9 0.0 0.0 0.0 1.5 7.8 0.0 0.0 7.2 0.0 0.0 0.0 0.0 4.0 0.9 0.0 0.0 0.0 0.0 1.2 0.0 0.1 3.0 0.0 0.0 0.0 0.4 0.5 0.1 53.2 19.6 1.0 0.1 0.0 0.0 13.0 FAXC "C6orf168, dJ273F20, MGC2817" ENSG00000146267 "Failed axon connections homolog, metaxin like GST domain containing" Q5TGI0 6 99271168-99350062 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 22.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 25.6;Excitatory neurons: 57.1;Inhibitory neurons: 60.1;Oligodendrocyte precursor cells: 43.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 26.0;HAP1: 23.8;SCLC-21H: 34.2;SH-SY5Y: 23.7;SK-MEL-30: 22.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039106 Uncertain Approved Nucleoplasm NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA039106: AB_10697546" "unprognostic (8.03e-2)" "unprognostic (4.91e-2)" "unprognostic (5.04e-3)" "unprognostic (6.44e-2)" "unprognostic (3.80e-1)" "unprognostic (5.00e-3)" "unprognostic (7.56e-2)" "unprognostic (7.29e-2)" "unprognostic (7.08e-2)" "unprognostic (1.34e-2)" "unprognostic (2.79e-3)" "unprognostic (2.47e-3)" "unprognostic (6.70e-4)" "unprognostic (1.13e-2)" "unprognostic (1.71e-1)" "unprognostic (4.86e-2)" "unprognostic (3.49e-3)" 0.7 2.2 11.0 1.5 12.7 0.0 3.2 9.3 19.0 2.5 2.0 22.7 1.5 6.5 11.0 6.2 3.7 2.4 0.8 14.1 7.6 2.7 0.0 1.7 0.1 7.2 5.6 2.2 2.5 6.5 15.9 0.8 6.3 8.2 2.9 10.4 7.4 10.6 0.5 0.9 3.3 7.8 4.4 0.4 7.1 2.1 8.5 2.2 1.7 0.6 0.1 14.3 2.9 11.4 4.0 3.2 10.3 14.3 0.0 0.0 3.8 5.0 3.2 8.1 7.0 1.9 1.3 0.0 0.6 1.0 26.0 0.1 23.8 4.7 7.0 0.0 11.8 0.1 1.9 0.7 0.6 0.0 0.0 0.5 7.5 0.2 3.8 5.9 0.0 2.0 0.5 0.0 2.7 7.0 0.0 0.0 12.2 0.0 4.8 0.0 1.0 0.0 4.3 0.3 34.2 23.7 4.5 3.2 22.6 4.2 10.0 0.0 1.0 2.5 4.7 0.0 15.5 0.0 0.0 0.0 0.1 0.0 19.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.0 12.7 9.3 19.0 14.1 7.6 7.2 5.6 6.3 4.4 8.5 11.4 0.2 25.6 15.2 5.5 0.5 0.4 4.2 4.2 5.7 14.4 5.3 9.0 1.1 0.0 8.1 1.8 10.4 1.2 0.4 0.2 9.8 2.3 2.6 0.6 1.0 1.7 0.0 0.0 57.1 0.7 0.2 1.4 0.0 0.4 3.8 0.4 1.4 0.1 0.2 3.3 60.1 0.2 4.1 0.6 1.1 5.0 0.0 1.2 1.8 2.8 0.1 3.6 2.1 43.7 4.4 1.0 0.1 1.9 0.1 4.8 0.0 1.0 2.1 13.6 0.0 0.2 1.3 1.3 8.9 1.2 0.3 0.3 1.2 0.2 0.4 1.2 FBRSL1 KIAA1545 ENSG00000112787 "Fibrosin like 1" Q9HCM7 12 132489551-132585188 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "NB-4: 90.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049880 Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 24: NB-4 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA049880: AB_2680930" "unprognostic (2.02e-1)" "unprognostic (6.67e-2)" "unprognostic (1.88e-2)" "unprognostic (7.75e-2)" "unprognostic (3.21e-1)" "unprognostic (2.59e-2)" "unprognostic (1.29e-1)" "unprognostic (1.83e-1)" "unprognostic (2.25e-1)" "unprognostic (1.57e-1)" "unprognostic (2.77e-3)" "prognostic unfavorable (9.82e-4)" "prognostic favorable (1.17e-4)" "unprognostic (1.13e-1)" "unprognostic (3.39e-1)" "unprognostic (1.09e-2)" "prognostic favorable (7.21e-4)" 12.3 19.2 16.3 8.7 13.1 10.1 13.2 20.7 21.2 17.8 7.2 20.5 11.2 18.6 7.7 15.6 18.7 4.1 31.1 16.2 6.7 19.3 26.8 16.2 8.5 10.0 7.7 22.3 39.2 7.3 28.7 5.7 8.0 22.0 3.6 5.9 14.7 7.2 31.9 19.4 23.3 4.1 4.7 28.3 21.4 29.1 9.6 6.2 15.7 9.4 4.7 17.8 15.7 10.2 11.7 18.5 8.7 14.8 3.7 4.5 64.4 10.9 3.1 7.1 4.3 32.7 6.9 19.0 18.4 3.6 6.1 22.6 9.3 6.1 2.3 14.7 47.6 23.2 11.0 25.0 8.0 24.7 23.4 4.1 10.7 6.6 4.8 6.5 7.0 15.9 49.9 3.8 3.1 29.8 33.7 90.0 22.7 8.4 33.4 50.9 9.3 13.2 6.2 11.2 33.4 28.0 10.2 15.8 14.1 3.6 18.6 23.7 11.1 7.6 18.5 13.7 13.9 24.6 13.0 12.0 8.8 23.8 9.4 1.2 0.4 1.2 0.3 0.3 0.3 0.8 0.3 0.3 0.3 0.6 0.3 0.4 0.5 0.2 0.7 1.0 0.6 0.3 16.3 13.1 20.7 21.2 16.2 6.7 10.0 7.7 8.0 4.7 9.6 10.2 14.9 3.2 5.2 24.2 12.8 9.2 7.1 3.3 11.4 28.9 20.7 18.5 13.7 4.3 4.0 11.0 41.7 6.9 19.8 24.0 7.9 6.2 1.4 16.8 17.9 8.8 31.0 12.0 17.0 7.6 5.8 11.8 15.3 22.0 1.3 22.6 7.5 22.2 6.9 11.8 17.1 21.7 0.0 11.6 11.1 2.0 16.1 16.4 5.4 15.0 7.7 9.3 6.2 12.5 16.8 9.0 15.0 15.4 11.9 16.0 13.3 6.4 6.4 22.7 6.6 12.7 11.5 5.7 8.0 10.8 10.4 11.5 10.9 12.7 18.7 10.4 FBXL5 "FBL4, FBL5, FLR1" ENSG00000118564 "F-box and leucine rich repeat protein 5" Q9UKA1 4 15604381-15681679 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 252.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 407.0" "Group enriched" "Detected in all" 5 "dendritic cells: 108.2;granulocytes: 407.0;monocytes: 225.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002484 Approved NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA002484: " "unprognostic (1.53e-1)" "unprognostic (8.08e-2)" "unprognostic (6.34e-3)" "unprognostic (1.08e-3)" "unprognostic (1.03e-1)" "unprognostic (1.53e-1)" "unprognostic (2.18e-2)" "unprognostic (6.12e-2)" "unprognostic (1.45e-1)" "unprognostic (2.42e-2)" "unprognostic (3.70e-2)" "unprognostic (5.14e-2)" "prognostic favorable (6.18e-5)" "unprognostic (1.02e-1)" "unprognostic (2.21e-1)" "unprognostic (5.39e-3)" "unprognostic (6.18e-2)" 72.8 50.9 49.0 40.2 53.9 110.9 51.9 56.3 65.5 53.8 50.3 51.3 29.8 42.1 63.5 43.0 46.1 51.6 49.5 48.1 51.2 128.0 77.4 48.8 35.3 49.9 52.6 41.5 32.7 59.4 44.4 37.1 50.1 51.5 36.2 48.0 36.9 56.4 80.1 36.3 31.7 55.1 50.9 45.1 41.5 68.0 52.2 46.3 70.6 85.5 32.6 53.9 37.7 55.2 23.3 17.8 42.3 23.9 65.0 63.9 13.4 30.4 37.2 32.7 45.9 14.3 34.1 18.1 14.2 36.4 57.8 8.5 21.9 36.5 50.3 17.7 11.2 17.8 12.9 16.9 65.3 21.7 16.4 59.0 48.4 30.4 46.9 74.9 86.8 15.7 15.2 14.8 99.1 10.5 41.3 33.4 22.3 19.1 15.8 29.5 43.0 14.8 51.8 32.9 20.4 19.2 28.4 10.0 32.8 57.7 16.2 35.8 20.8 37.8 10.7 26.0 38.0 20.1 22.2 16.8 32.4 37.7 46.6 204.3 225.4 115.2 46.2 112.9 44.9 33.5 42.5 44.7 108.2 31.3 44.0 44.8 407.0 42.4 101.7 16.6 40.6 206.8 49.0 53.9 56.3 65.5 48.1 51.2 49.9 52.6 50.1 50.9 52.2 55.2 37.0 44.8 62.0 63.6 31.3 27.3 37.2 40.5 62.0 52.3 34.6 28.2 88.1 41.5 46.9 36.8 6.2 53.3 38.9 24.4 78.2 29.2 80.3 32.5 41.2 42.5 25.9 29.9 73.6 23.3 41.8 47.0 36.2 42.1 39.9 38.6 40.0 69.1 48.5 40.4 78.7 20.1 32.6 109.9 28.4 52.9 39.7 81.1 30.2 63.7 138.4 36.2 44.3 65.9 120.2 18.8 20.4 58.3 39.1 30.8 37.2 252.3 61.9 41.1 59.2 42.1 46.2 188.5 73.5 63.1 26.1 26.4 45.4 38.4 25.6 32.7 FBXO15 "FBX15, MGC39671" ENSG00000141665 "F-box protein 15" Q8NCQ5 18 74073353-74147843 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 4.1;testis: 7.1" "Cell type enhanced" "Detected in many" "Early spermatids: 36.0;Endometrial ciliated cells: 41.1;Oligodendrocytes: 19.3;Respiratory ciliated cells: 59.2;Spermatocytes: 41.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "naive CD4 T-cell: 1.6" "Lineage enriched" "Detected in single" 6 "T-cells: 1.6" "Cell line enhanced" "Detected in some" "GAMG: 1.6;JURKAT: 2.6;SCLC-21H: 2.7" "Not detected" "Not detected" "Region enriched" "Detected in many" 6 "basal ganglia: 17.6" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (1.69e-2)" "unprognostic (1.97e-1)" "unprognostic (6.34e-6)" "unprognostic (1.65e-2)" "unprognostic (4.20e-1)" "unprognostic (6.77e-2)" "unprognostic (1.64e-1)" "unprognostic (5.93e-2)" "unprognostic (1.27e-1)" "unprognostic (3.38e-2)" "unprognostic (1.00e-2)" "unprognostic (9.62e-2)" "unprognostic (4.46e-5)" "unprognostic (4.64e-2)" "unprognostic (3.35e-2)" "unprognostic (1.62e-4)" "unprognostic (2.87e-1)" 0.1 0.7 0.9 0.0 1.2 0.1 0.3 1.0 1.1 0.5 1.1 0.1 0.1 0.1 2.2 0.1 4.1 0.2 0.1 1.0 1.1 1.1 0.4 0.4 0.1 2.6 3.4 0.3 0.4 0.6 1.4 0.0 2.4 0.2 0.0 3.4 0.3 0.7 0.1 0.2 0.1 0.0 1.8 0.3 0.2 7.1 0.9 0.2 0.6 0.0 0.0 0.1 0.1 2.9 0.0 0.1 0.2 0.2 0.1 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.6 0.7 0.0 0.0 0.3 0.6 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.3 0.3 0.0 2.6 0.0 0.2 0.1 0.1 0.1 0.1 0.5 0.3 0.8 0.3 0.0 0.0 0.3 0.0 2.7 0.8 0.0 0.0 1.0 0.3 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.1 1.2 1.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.5 0.2 0.0 0.2 1.6 0.9 0.0 0.0 0.1 0.2 0.0 0.4 0.9 1.2 1.0 1.1 1.0 1.1 2.6 3.4 2.4 1.8 0.9 2.9 0.3 6.4 1.1 12.4 1.0 0.3 0.8 3.9 0.0 8.1 1.5 1.8 0.6 0.0 5.9 1.8 0.0 0.5 0.1 0.1 3.9 0.9 36.0 41.1 0.5 0.3 0.0 0.4 6.4 0.2 0.7 0.2 0.0 1.2 0.0 2.2 0.7 0.4 3.1 5.0 8.8 0.2 0.0 0.6 0.3 17.8 1.2 0.4 0.0 2.8 0.0 7.8 0.0 9.0 19.3 0.1 0.1 1.5 0.0 0.2 0.0 5.8 59.2 10.3 0.0 0.8 2.1 41.5 11.7 0.0 0.0 0.4 0.4 0.3 0.2 0.6 FBXO24 FBX24 ENSG00000106336 "F-box protein 24" O75426 7 100583982-100601117 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 34 "testis: 81.2" "Group enriched" "Detected in some" 45 "Early spermatids: 517.1;Late spermatids: 594.8" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "U-2 OS: 2.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA050951 Enhanced NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 34: Spermatids - Unknown function" "HPA050951: AB_2681286" "unprognostic (3.73e-1)" "unprognostic (2.83e-1)" "unprognostic (3.76e-4)" "unprognostic (3.52e-2)" "unprognostic (3.19e-2)" "unprognostic (2.63e-2)" "unprognostic (1.34e-1)" "unprognostic (3.86e-4)" "unprognostic (2.31e-2)" "unprognostic (1.15e-2)" "unprognostic (9.34e-3)" "unprognostic (1.44e-1)" "unprognostic (9.20e-2)" "unprognostic (7.71e-2)" "unprognostic (1.27e-1)" "unprognostic (1.05e-2)" "unprognostic (1.48e-2)" 0.3 0.4 0.2 0.7 0.4 0.7 0.5 2.3 0.9 1.4 0.1 0.7 0.2 1.1 0.4 0.7 1.0 0.9 0.7 0.3 0.0 1.0 0.7 0.5 1.2 0.7 0.2 1.6 0.6 0.2 0.9 0.7 0.6 1.0 0.2 1.0 1.2 0.6 0.4 1.3 0.6 0.4 0.1 0.8 0.4 81.2 0.3 0.2 0.5 0.3 0.4 0.4 1.0 0.4 0.5 0.4 0.6 0.8 1.7 0.0 0.3 0.4 0.2 0.2 0.1 0.8 1.4 0.8 0.3 0.0 0.2 0.4 0.0 0.2 0.0 0.3 1.0 0.1 0.2 0.0 0.3 0.0 1.2 0.8 0.8 0.0 0.0 0.0 0.2 1.0 0.2 1.1 0.0 1.3 0.2 1.7 0.9 1.2 0.5 0.0 0.0 0.2 0.0 0.5 0.1 1.0 0.7 1.0 0.5 1.3 0.8 0.3 0.0 0.6 2.5 2.0 0.1 0.6 0.3 0.2 0.2 0.9 1.1 0.0 0.1 0.0 0.0 0.1 0.1 0.3 0.1 0.0 0.2 0.1 0.1 0.2 0.3 0.0 0.0 0.5 0.3 0.2 0.2 0.4 2.3 0.9 0.3 0.0 0.7 0.2 0.6 0.1 0.3 0.4 0.3 0.0 0.0 2.3 0.1 0.3 0.7 0.6 0.6 0.6 0.4 0.3 1.3 0.0 0.2 0.0 8.4 0.4 1.4 0.3 0.0 0.6 517.1 0.8 0.4 0.4 0.0 0.0 0.3 0.6 0.6 0.6 0.0 0.2 0.0 0.3 0.7 0.2 0.3 0.0 0.7 0.2 0.0 0.0 0.4 594.8 3.7 0.3 0.0 1.0 0.6 0.7 0.0 0.0 0.5 0.2 0.1 3.8 0.0 0.3 0.3 0.2 0.8 1.4 0.0 0.4 0.8 12.2 5.3 0.4 0.3 0.1 0.5 0.3 0.4 0.4 FBXO25 FBX25 ENSG00000147364 "F-box protein 25" Q8TCJ0 8 406428-477967 "Disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 97.8" "Cell type enhanced" "Detected in all" "Early spermatids: 625.7;Late spermatids: 312.5;Spermatocytes: 640.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "JURKAT: 58.7;SK-MEL-30: 61.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 37: B-cells - Transcription" "Cluster 22: Non-specific - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (1.63e-1)" "prognostic favorable (5.38e-5)" "unprognostic (2.74e-2)" "unprognostic (5.11e-3)" "unprognostic (2.48e-1)" "unprognostic (1.25e-2)" "unprognostic (1.86e-1)" "unprognostic (9.23e-3)" "unprognostic (2.03e-2)" "unprognostic (1.55e-1)" "unprognostic (2.39e-3)" "unprognostic (3.30e-1)" "prognostic favorable (1.41e-4)" "unprognostic (1.71e-1)" "unprognostic (3.94e-2)" "unprognostic (2.11e-3)" "unprognostic (2.41e-1)" 14.4 20.4 9.3 7.6 9.4 9.1 13.8 13.4 11.8 9.1 8.3 16.6 15.4 8.4 16.8 10.0 8.6 9.3 15.3 8.8 9.2 15.8 30.0 10.4 12.0 8.8 10.2 8.8 28.6 14.2 12.1 6.8 9.1 24.9 18.7 7.2 16.3 10.5 18.3 12.4 11.1 11.0 8.4 8.1 15.1 97.8 8.6 20.7 18.6 19.7 12.1 11.3 9.0 11.4 13.4 10.6 4.5 8.8 6.9 4.4 18.6 12.6 18.5 11.8 18.1 6.0 12.7 0.3 3.4 19.4 17.8 8.5 8.7 24.5 16.1 10.0 14.5 7.1 6.3 28.3 20.5 11.4 13.7 12.7 37.6 3.6 18.7 17.9 5.0 58.7 8.4 0.1 13.9 12.8 50.8 13.6 2.1 29.0 4.6 2.4 3.4 18.1 15.4 22.5 13.7 14.4 12.7 4.2 61.5 11.2 9.0 8.1 7.5 4.8 4.1 0.8 10.1 9.2 14.4 13.6 13.0 4.7 14.7 1.6 9.1 6.6 9.0 10.8 11.1 16.2 10.7 8.5 9.1 10.9 9.5 9.4 0.7 9.9 9.9 9.0 12.5 6.9 9.3 9.4 13.4 11.8 8.8 9.2 8.8 10.2 9.1 8.4 8.6 11.4 21.3 19.2 28.5 15.3 24.2 34.8 19.6 28.0 19.9 31.8 35.9 21.7 36.6 42.9 20.4 35.0 10.4 20.0 26.8 30.4 72.4 53.3 625.7 20.0 17.8 25.7 43.3 12.6 20.5 102.6 18.9 18.2 16.3 27.4 20.3 15.4 28.2 77.0 25.4 53.8 20.0 58.2 42.7 32.7 24.2 312.5 38.8 17.4 39.2 11.2 36.2 22.1 38.1 8.5 28.3 51.5 41.2 29.3 21.4 39.1 34.9 58.3 13.2 36.3 26.3 17.8 16.2 640.9 142.1 17.4 40.5 16.1 19.5 14.4 47.2 21.8 FBXO33 Fbx33 ENSG00000165355 "F-box protein 33" Q7Z6M2 14 39397669-39432500 "Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 52.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 82.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046657 Approved Approved Nucleoplasm NA NA "Cluster 15: NK-cells - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "HPA046657: AB_10960398" "unprognostic (8.84e-3)" "unprognostic (6.72e-2)" "unprognostic (3.65e-2)" "unprognostic (2.79e-1)" "unprognostic (1.08e-1)" "unprognostic (3.20e-2)" "unprognostic (1.19e-1)" "prognostic favorable (4.94e-4)" "unprognostic (1.24e-1)" "unprognostic (2.70e-2)" "unprognostic (1.17e-1)" "unprognostic (2.40e-1)" "prognostic favorable (4.58e-4)" "unprognostic (9.61e-2)" "unprognostic (4.54e-1)" "unprognostic (4.41e-2)" "unprognostic (8.58e-3)" 7.0 9.6 12.2 8.1 12.6 52.6 6.5 10.8 16.2 8.0 16.7 5.9 7.2 6.5 10.1 5.2 6.0 7.3 5.3 14.9 12.9 7.3 6.9 7.9 9.4 12.4 10.8 6.1 5.9 13.2 10.8 7.8 12.5 7.5 5.7 8.4 6.7 7.4 3.0 5.7 5.6 6.6 9.8 7.8 6.0 12.1 11.6 11.8 11.6 6.7 9.8 7.2 4.9 12.5 12.8 7.8 7.0 10.8 24.7 11.5 11.6 12.6 16.9 6.9 8.0 4.7 11.1 14.3 15.2 19.7 6.9 6.4 18.3 12.4 12.3 13.7 11.8 5.7 10.5 12.2 7.0 21.7 20.9 10.7 13.2 11.8 3.8 11.9 5.8 14.0 5.0 12.6 13.6 13.7 19.4 13.5 7.2 11.5 11.6 16.6 11.4 13.0 13.2 16.1 12.1 5.5 11.3 11.8 14.0 10.4 8.7 13.7 7.5 11.6 10.4 17.4 10.1 17.0 21.6 22.6 9.0 10.1 8.8 0.9 0.9 1.8 1.6 1.1 1.4 1.2 1.6 1.7 0.8 1.1 2.2 2.1 3.9 2.8 1.1 0.7 1.7 0.6 12.2 12.6 10.8 16.2 14.9 12.9 12.4 10.8 12.5 9.8 11.6 12.5 14.7 9.6 20.1 21.9 25.7 34.5 13.6 6.4 27.9 24.0 19.1 16.4 8.9 4.3 8.1 9.2 43.8 8.4 40.8 18.0 7.9 8.1 42.1 25.7 14.3 14.7 23.9 16.2 82.6 9.3 9.5 14.8 12.8 39.8 10.2 10.1 13.9 10.6 10.5 28.6 46.7 14.2 2.0 19.2 23.3 10.7 8.4 22.6 19.6 23.4 14.8 12.4 10.3 34.7 36.7 14.0 10.1 5.3 32.7 21.5 13.9 4.0 8.4 17.9 0.0 18.8 17.8 28.5 12.2 24.0 56.4 21.2 31.4 8.0 13.7 24.7 FBXO36 "Fbx36, FLJ37592" ENSG00000153832 "F-box protein 36" Q8NEA4 2 229922302-230013119 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 35.5;Early spermatids: 61.7;Endometrial ciliated cells: 40.8;Respiratory ciliated cells: 53.0;Spermatocytes: 55.8" "Cancer enhanced" "Detected in all" "testis cancer: 9.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053865 Approved Nucleoplasm,Nucleoli NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Nucleoli" "HPA053865: AB_2682282" "unprognostic (4.39e-3)" "unprognostic (6.51e-2)" "unprognostic (2.38e-2)" "prognostic favorable (2.28e-4)" "unprognostic (2.43e-1)" "unprognostic (1.06e-1)" "unprognostic (1.15e-2)" "unprognostic (2.38e-2)" "unprognostic (2.12e-1)" "unprognostic (1.96e-1)" "unprognostic (1.28e-2)" "unprognostic (8.04e-2)" "unprognostic (7.79e-3)" "unprognostic (3.72e-2)" "unprognostic (1.86e-1)" "unprognostic (1.03e-2)" "unprognostic (2.68e-1)" 1.9 3.7 4.6 0.7 4.2 0.8 3.5 4.3 4.5 3.0 3.9 1.2 1.4 2.5 2.8 1.6 11.0 1.7 1.2 3.7 4.4 5.1 1.6 2.3 0.9 5.8 5.6 2.4 1.6 4.3 2.7 1.6 5.1 2.9 1.2 9.0 2.3 2.5 0.8 3.0 1.4 1.7 5.4 0.8 1.7 6.0 4.4 1.5 7.4 0.8 1.0 1.3 1.5 5.1 1.0 1.9 2.3 0.9 1.1 6.8 4.6 1.2 3.2 1.7 2.9 0.7 3.1 0.1 0.6 2.2 2.1 0.8 1.1 0.6 2.9 0.3 0.7 0.4 0.6 1.2 4.4 0.8 0.3 7.2 5.2 3.2 2.4 2.2 1.8 3.4 1.4 0.6 2.0 4.2 1.7 1.9 6.1 2.2 2.2 2.0 0.6 0.5 3.0 0.8 2.2 2.8 2.0 1.6 0.8 2.6 3.4 1.4 1.3 2.8 1.0 4.6 0.5 2.1 1.8 0.7 3.4 0.4 2.1 0.0 0.5 0.0 0.8 0.4 0.6 1.1 0.6 0.6 1.3 0.7 1.4 0.8 0.2 1.0 0.3 0.6 1.2 0.5 4.6 4.2 4.3 4.5 3.7 4.4 5.8 5.6 5.1 5.4 4.4 5.1 3.1 9.6 1.1 11.4 1.1 3.8 2.9 8.3 1.2 8.3 4.3 4.3 3.7 0.0 9.9 11.0 35.5 1.9 0.6 2.3 15.6 6.2 61.7 40.8 4.9 2.3 0.0 2.5 19.5 6.6 2.0 3.7 3.1 4.7 0.0 4.2 1.4 2.7 1.1 10.1 22.1 1.6 14.2 1.6 3.0 10.5 3.4 1.2 3.6 5.6 2.9 7.5 4.1 12.5 12.5 6.2 0.5 4.1 0.7 3.0 2.2 12.2 53.0 28.8 6.6 2.8 4.2 55.8 8.6 3.2 4.5 2.2 1.5 9.1 1.4 1.9 FBXO39 "CT144, Fbx39, MGC35179" ENSG00000177294 "F-box protein 39" Q8N4B4 17 6776215-6797101 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 29 "testis: 30.3" "Group enriched" "Detected in some" 160 "Early spermatids: 346.2;Late spermatids: 553.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Karpas-707: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 83: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 34: Spermatids - Unknown function" "unprognostic (1.16e-1)" "unprognostic (6.73e-2)" "unprognostic (1.69e-2)" "unprognostic (1.78e-2)" "unprognostic (2.15e-2)" "unprognostic (7.19e-2)" "unprognostic (7.93e-2)" "unprognostic (2.89e-1)" "unprognostic (3.30e-2)" "unprognostic (1.18e-1)" "unprognostic (1.72e-3)" "unprognostic (2.36e-1)" "unprognostic (3.73e-9)" "unprognostic (5.11e-2)" "unprognostic (2.67e-1)" "unprognostic (5.93e-2)" "unprognostic (3.79e-2)" 0.3 0.0 0.2 0.0 0.2 0.2 0.2 0.1 0.5 0.5 0.1 0.1 0.1 0.2 0.2 0.2 0.3 0.2 0.1 0.2 0.2 0.1 0.8 0.2 0.1 0.4 0.2 1.0 0.0 0.0 0.1 0.2 0.2 0.2 0.0 0.0 0.3 0.0 0.0 0.2 0.1 0.0 0.3 0.3 0.0 30.3 0.2 0.1 0.1 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.3 0.2 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.3 0.3 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.5 0.2 0.2 0.4 0.2 0.2 0.3 0.2 0.1 0.7 0.0 0.0 1.3 0.0 0.0 0.0 0.5 2.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 346.2 0.1 0.2 0.5 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 553.7 2.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.3 1.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 FBXO47 ENSG00000204952 "F-box protein 47" Q5MNV8 17 38936432-38967403 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 39 "testis: 3.9" "Cell type enriched" "Detected in some" 6 "Spermatocytes: 74.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA057438 Uncertain NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA057438: AB_2683441" "unprognostic (1.53e-1)" "unprognostic (2.98e-1)" "unprognostic (2.82e-1)" "unprognostic (3.92e-1)" "unprognostic (6.04e-2)" "unprognostic (2.59e-2)" "unprognostic (2.29e-2)" "unprognostic (6.85e-2)" "unprognostic (4.15e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 1.2 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 6.6 0.0 0.0 74.1 12.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 FBXO6 "FBG2, FBS2, FBX6, Fbx6b" ENSG00000116663 "F-box protein 6" Q9NRD1 1 11664200-11674354 "Cancer-related genes, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway, Unfolded protein response" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 60.6;Late spermatids: 117.8;NK-cells: 60.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051175 Approved NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 63: NK-cells & T-cells - Immune response" "HPA051175: AB_2681372" "unprognostic (3.23e-3)" "unprognostic (2.58e-2)" "unprognostic (8.27e-2)" "unprognostic (2.69e-3)" "unprognostic (1.11e-1)" "unprognostic (6.64e-2)" "unprognostic (9.46e-3)" "unprognostic (1.22e-1)" "unprognostic (1.18e-1)" "prognostic favorable (7.12e-4)" "unprognostic (1.47e-2)" "unprognostic (3.40e-1)" "prognostic unfavorable (7.83e-6)" "unprognostic (2.65e-2)" "unprognostic (2.11e-1)" "unprognostic (5.23e-2)" "prognostic favorable (5.90e-4)" 6.5 10.7 9.9 11.8 10.1 20.3 6.7 10.3 12.4 7.6 8.2 7.6 13.5 5.0 6.0 10.3 14.1 8.7 10.0 9.8 11.5 7.8 18.5 11.4 18.3 9.9 10.5 5.9 13.8 13.5 6.1 2.6 9.7 8.7 6.8 3.6 13.0 8.4 18.7 9.5 8.2 7.4 10.0 13.0 9.8 10.8 12.6 7.1 6.7 14.5 11.1 9.5 7.0 9.8 10.0 7.3 0.8 0.4 2.1 6.8 4.5 4.2 6.6 20.1 9.2 7.6 8.3 0.3 18.7 7.0 5.5 0.2 6.8 7.5 1.5 26.3 1.0 0.2 1.0 7.7 15.4 9.4 0.1 7.9 15.8 2.5 6.3 4.3 2.6 10.3 22.7 18.7 1.8 19.1 3.4 7.8 0.8 10.2 9.7 2.3 0.1 0.7 6.9 1.4 1.6 2.0 9.3 10.9 14.3 1.8 10.5 10.2 2.0 1.0 0.8 2.7 0.3 10.0 7.5 3.9 1.2 21.6 1.8 17.1 49.5 65.0 47.0 75.0 25.4 15.3 12.0 31.3 66.5 15.0 7.1 23.7 41.4 41.4 91.0 27.3 13.1 36.6 9.9 10.1 10.3 12.4 9.8 11.5 9.9 10.5 9.7 10.0 12.6 9.8 6.0 6.4 6.9 3.3 8.4 7.0 6.6 14.6 4.0 4.3 8.3 7.4 6.8 2.8 15.0 9.2 2.1 1.1 19.5 10.7 0.0 14.5 60.6 15.7 4.5 4.0 4.9 1.7 1.8 38.5 9.2 7.8 8.6 5.3 3.8 2.2 8.2 19.9 26.2 5.0 2.6 8.3 8.2 15.4 34.7 117.8 8.1 18.3 7.2 1.0 37.8 9.0 60.8 0.0 1.3 13.0 10.8 11.3 12.2 11.3 14.3 15.6 36.5 7.8 0.0 3.3 4.0 4.0 11.9 7.3 9.8 1.8 16.0 1.8 9.2 11.2 FCGR2A "CD32, CD32A, CDw32, FCG2, FCGR2, FCGR2A1, IGFR2" ENSG00000143226 "Fc fragment of IgG receptor IIa" P12318 1 161505430-161524013 "CD markers, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Immunity "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 101.7;placenta: 107.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 178.2;Kupffer cells: 159.1;Langerhans cells: 336.6;Macrophages: 305.0;monocytes: 97.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "neutrophil: 2322.4" "Lineage enriched" "Detected in many" 6 "granulocytes: 2322.4" "Cell line enhanced" "Detected in some" "HEL: 29.4;HMC-1: 56.2;K-562: 17.9;NB-4: 15.8;THP-1: 61.9;U-937: 26.7" "HPA010718, HPA010776, HPA014730" Enhanced Supported "Golgi apparatus,Plasma membrane" NA NA 46000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 19: Lung - Lung function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "Golgi apparatus" "HPA010718: AB_1078463, HPA010776: , HPA014730: AB_2669074" "unprognostic (2.57e-2)" "unprognostic (1.16e-1)" "unprognostic (1.48e-2)" "unprognostic (4.12e-2)" "unprognostic (5.89e-2)" "unprognostic (6.17e-2)" "unprognostic (1.24e-2)" "unprognostic (1.17e-1)" "unprognostic (7.63e-2)" "unprognostic (1.17e-3)" "unprognostic (2.43e-2)" "unprognostic (2.91e-1)" "prognostic unfavorable (6.49e-7)" "unprognostic (8.85e-3)" "unprognostic (6.47e-3)" "unprognostic (1.54e-1)" "unprognostic (3.42e-2)" 68.0 24.8 7.3 101.7 6.6 48.6 13.3 8.0 12.1 18.1 13.9 16.0 8.1 7.3 4.3 11.7 14.6 36.8 11.5 6.5 11.5 12.7 12.3 77.5 16.1 15.1 11.4 7.2 12.7 8.5 7.6 107.3 13.3 6.1 21.0 2.3 9.9 9.6 2.6 3.5 10.8 40.9 11.9 61.8 10.1 4.4 13.8 9.8 6.4 10.2 7.7 68.3 5.2 21.8 0.0 0.0 0.0 2.4 0.0 0.3 0.0 0.0 0.5 0.0 0.1 0.0 0.0 2.3 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 29.4 0.3 0.0 0.7 8.6 56.2 0.5 0.0 0.0 0.0 0.7 0.1 0.0 17.9 0.5 0.0 0.0 0.4 15.8 0.0 0.0 1.1 0.2 1.2 8.1 0.0 0.0 0.1 0.0 0.0 0.0 4.6 0.0 0.0 61.9 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.7 0.4 26.7 6.6 2.4 358.3 421.8 0.7 268.4 1.0 3.2 0.5 0.4 89.9 1.7 0.4 0.7 2322.4 0.4 232.7 3.8 0.9 170.3 7.3 6.6 8.0 12.1 6.5 11.5 15.1 11.4 13.3 11.9 13.8 21.8 2.3 22.4 49.1 0.0 8.6 8.7 0.9 0.3 1.2 0.4 1.1 3.8 1.8 2.8 12.1 0.0 0.0 1.0 3.4 0.1 9.8 0.2 38.2 0.1 0.8 15.6 0.0 3.0 0.1 0.6 1.6 8.9 1.1 0.1 30.4 0.1 3.9 2.1 178.2 0.0 0.1 0.0 0.0 159.1 336.6 66.5 1.5 305.0 17.8 12.2 97.3 0.5 7.2 1.0 0.6 0.5 0.0 0.0 4.6 0.3 0.0 9.6 3.7 0.2 6.6 1.5 6.0 0.4 0.6 0.8 7.7 1.6 4.8 0.2 0.1 0.4 FCGR2B "CD32, CD32B, FCG2, FCGR2" ENSG00000072694 "Fc fragment of IgG receptor IIb" P31994 1 161663147-161678654 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" "Host-virus interaction" "IgG-binding protein, Receptor" "Cancer-related genes, FDA approved drug targets, Proto-oncogene, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 9 "placenta: 398.2" "Cell type enhanced" "Detected in many" "B-cells: 75.0;Hepatic stellate cells: 333.8;Langerhans cells: 244.0;Macrophages: 145.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 327.2;memory B-cell: 202.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "Daudi: 24.9;HMC-1: 31.2;NB-4: 7.3;RPMI-8226: 11.7" "CAB007796, HPA014730" Enhanced NA NA "Cluster 10: Basophils - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "CAB007796: AB_562288, HPA014730: AB_2669074" "unprognostic (1.58e-1)" "unprognostic (5.14e-2)" "unprognostic (3.32e-3)" "unprognostic (3.12e-2)" "unprognostic (6.79e-3)" "unprognostic (4.05e-3)" "unprognostic (1.27e-1)" "unprognostic (4.65e-3)" "unprognostic (1.91e-1)" "unprognostic (4.72e-2)" "unprognostic (2.89e-2)" "unprognostic (3.49e-1)" "prognostic unfavorable (8.82e-4)" "unprognostic (3.51e-2)" "unprognostic (6.36e-2)" "unprognostic (4.31e-1)" "unprognostic (3.37e-1)" 30.4 7.5 0.9 12.2 1.3 1.7 15.4 1.3 3.3 9.7 4.2 10.3 3.0 2.6 2.8 11.4 4.4 13.0 7.9 0.7 1.1 4.2 42.4 21.7 15.8 4.5 1.1 4.8 4.7 2.8 1.4 398.2 2.2 1.8 11.0 1.1 7.0 2.8 2.2 4.8 16.0 16.6 2.2 25.5 4.9 2.5 1.4 7.4 4.2 13.7 29.6 18.7 3.1 5.8 0.0 0.1 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 31.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 7.3 0.1 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.1 0.1 0.0 0.0 2.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 2.8 0.0 327.2 8.5 26.4 1.4 9.7 0.6 202.8 0.7 1.1 72.4 160.4 0.1 1.4 53.6 0.7 9.5 0.1 0.1 13.0 0.9 1.3 1.3 3.3 0.7 1.1 4.5 1.1 2.2 2.2 1.4 5.8 2.2 0.0 3.9 0.0 75.0 5.4 0.1 0.0 0.0 0.0 0.3 0.9 2.1 2.8 1.3 0.0 0.0 0.2 5.6 0.0 0.0 0.0 4.8 0.0 0.0 49.8 0.0 3.2 0.0 0.0 0.2 1.7 1.1 0.0 2.5 0.2 333.8 8.2 7.6 0.0 0.0 0.0 0.0 47.4 244.0 4.2 0.6 145.5 23.2 0.0 9.5 0.0 5.2 0.0 0.1 0.0 0.0 0.0 45.4 0.0 0.0 0.3 0.0 0.0 0.0 1.7 2.5 0.3 0.2 0.7 3.1 0.4 5.8 0.1 0.1 0.0 FCN3 "FCNH, HAKA1" ENSG00000142748 "Ficolin 3" O75636 1 27369110-27374824 "Disease related genes, Plasma proteins, Predicted secreted proteins" "Complement activation lectin pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "liver: 278.3;lung: 724.6" "Cell type enriched" "Detected in some" 16 "Hepatic stellate cells: 2828.6" "Cancer enhanced" "Detected in many" "renal cancer: 7.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" CAB025945 Approved "Secreted to blood" NA NA 22800000000 14000000000 "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB025945: " "unprognostic (1.59e-1)" "unprognostic (5.25e-2)" "unprognostic (1.55e-2)" "unprognostic (8.27e-2)" "unprognostic (1.45e-3)" "unprognostic (1.27e-2)" "unprognostic (1.87e-3)" "unprognostic (1.21e-1)" "unprognostic (6.28e-4)" "unprognostic (7.07e-2)" "unprognostic (2.86e-2)" "unprognostic (3.23e-2)" "unprognostic (3.87e-3)" "unprognostic (4.14e-2)" "unprognostic (1.02e-1)" "unprognostic (6.97e-2)" "unprognostic (1.61e-2)" 62.6 35.9 1.1 5.7 1.0 0.0 40.8 1.1 1.6 2.7 10.0 4.1 0.8 3.9 0.1 2.8 3.0 1.6 62.1 1.4 1.1 55.2 278.3 724.6 4.3 1.2 1.2 2.4 12.5 2.7 6.6 22.6 1.2 5.3 0.5 0.0 2.5 0.5 9.0 1.9 6.7 1.8 1.2 11.3 8.4 2.4 1.2 0.4 20.4 7.5 0.3 3.0 1.9 1.0 0.1 0.2 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.0 1.1 1.6 1.4 1.1 1.2 1.2 1.2 1.2 1.2 1.0 94.1 0.0 9.3 0.0 16.6 0.8 0.6 0.5 0.6 0.0 0.8 2.8 2.4 52.9 0.2 0.0 0.0 0.1 0.2 0.0 0.0 0.1 1.5 0.4 0.2 155.1 0.0 136.4 0.1 0.0 0.0 3.8 0.5 0.2 3.8 0.0 2828.6 31.8 0.3 0.0 0.1 0.0 2.0 168.6 0.3 2.7 3.4 2.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.6 0.0 0.1 5.1 0.0 0.0 1.0 2.7 0.5 0.5 1.0 1.1 0.0 4.9 0.5 0.0 0.3 FCRL3 "CD307c, FCRH3, IFGP3, IRTA3, SPAP2, SPAP2a, SPAP2b, SPAP2c, SPAP2d, SPAP2e" ENSG00000160856 "Fc receptor like 3" Q96P31 1 157674321-157700769 "CD markers, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "lymphoid tissue: 49.5" "Cell type enhanced" "Detected in some" "B-cells: 54.3;dendritic cells: 21.2;Early spermatids: 8.0;Late spermatids: 9.1;NK-cells: 30.9;T-cells: 12.4" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "naive B-cell: 35.3" "Group enriched" "Detected in many" 54 "B-cells: 35.3;NK-cells: 20.4;T-cells: 19.0" "Cell line enriched" "Detected in some" 7 "Daudi: 9.9" "Low region specificity" "Detected in some" HPA048022 Enhanced NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA048022: AB_2732541" "unprognostic (6.73e-3)" "unprognostic (5.06e-4)" "unprognostic (1.13e-2)" "unprognostic (2.08e-4)" "unprognostic (3.86e-1)" "unprognostic (1.74e-5)" "unprognostic (1.09e-2)" "unprognostic (4.29e-3)" "unprognostic (3.69e-3)" "unprognostic (2.46e-4)" "unprognostic (1.13e-1)" "unprognostic (2.55e-2)" "unprognostic (2.01e-4)" "unprognostic (1.55e-1)" "unprognostic (1.29e-1)" "unprognostic (2.21e-1)" "unprognostic (6.69e-2)" 0.4 0.0 0.0 14.1 0.0 1.1 0.1 0.0 0.0 0.1 0.0 1.1 0.3 0.2 0.1 0.1 0.1 1.0 0.2 0.0 0.0 0.2 0.8 0.9 49.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 1.2 0.0 0.8 0.0 0.1 0.0 8.7 0.1 0.0 27.5 1.5 0.2 0.0 4.6 0.4 0.1 36.6 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.0 0.0 0.1 0.0 0.0 19.0 0.0 1.8 30.3 2.6 13.2 0.0 35.3 0.2 8.3 0.4 20.4 0.0 0.0 11.3 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 54.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 21.2 0.0 0.0 0.0 8.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.3 0.1 0.0 0.1 0.0 0.0 1.2 0.0 9.1 0.0 0.4 0.0 1.0 0.9 0.0 30.9 0.5 0.0 0.0 1.1 0.0 3.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 12.4 0.0 0.0 0.0 FDXR "ADR, ADXR" ENSG00000161513 "Ferredoxin reductase" P22570 17 74862497-74873031 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol metabolism, Electron transport, Lipid metabolism, Steroid metabolism, Sterol metabolism, Transport" Oxidoreductase "Deafness, Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "adrenal gland: 343.1" "Group enriched" "Detected in many" 7 "Granulosa cells: 329.3;Theca cells: 794.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 89.5;Hep G2: 173.5" "Low region specificity" "Detected in all" "CAB008597, CAB009818, HPA044393, HPA053673" Enhanced Enhanced Mitochondria NA NA "Cluster 15: NK-cells - Transcription" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 52: Non-specific - Transcription" Mitochondria "CAB008597: AB_1615557, CAB009818: AB_2102601, HPA044393: AB_2678927, HPA053673: AB_2682225" "unprognostic (2.69e-2)" "unprognostic (1.17e-3)" "unprognostic (7.51e-2)" "prognostic favorable (2.38e-4)" "unprognostic (3.43e-2)" "unprognostic (1.20e-1)" "unprognostic (1.53e-1)" "unprognostic (1.68e-2)" "unprognostic (2.29e-1)" "unprognostic (1.50e-1)" "unprognostic (1.09e-1)" "unprognostic (6.30e-2)" "unprognostic (1.42e-2)" "unprognostic (1.19e-2)" "unprognostic (4.50e-2)" "unprognostic (4.03e-2)" "unprognostic (2.13e-1)" 3.9 343.1 6.9 2.4 8.4 2.2 3.8 7.8 8.1 7.8 8.6 9.7 4.6 6.7 5.1 26.0 12.9 4.1 6.0 6.6 6.7 6.5 14.9 5.3 2.9 7.6 7.9 20.5 12.9 5.9 4.1 3.0 7.5 6.7 3.2 0.5 7.1 4.4 7.7 16.4 5.6 2.3 7.4 33.9 7.6 45.6 7.0 4.7 6.0 1.7 2.5 6.2 10.5 7.5 12.5 65.6 9.6 10.8 6.8 9.1 89.5 14.8 15.9 8.6 17.1 18.3 10.8 29.6 2.6 6.2 4.8 24.9 6.9 18.4 2.5 27.9 15.2 22.6 10.6 173.5 19.0 5.0 75.1 29.2 20.3 9.1 3.1 7.0 43.9 10.9 36.1 4.8 13.4 53.4 19.7 10.6 5.5 11.8 14.5 10.6 16.4 16.2 7.1 21.0 5.2 12.1 10.0 21.7 11.2 10.9 47.4 4.7 20.5 5.9 51.9 9.4 7.4 12.7 2.3 6.5 16.1 7.7 20.6 1.7 6.0 5.0 5.6 4.5 5.0 4.8 5.1 6.8 7.3 2.4 4.4 5.4 2.0 10.3 3.4 1.4 15.4 5.2 6.9 8.4 7.8 8.1 6.6 6.7 7.6 7.9 7.5 7.4 7.0 7.5 4.0 3.2 3.9 7.5 8.2 9.7 17.8 42.6 17.1 4.9 6.6 8.4 3.8 5.7 23.3 9.2 4.2 53.2 2.8 18.6 5.9 11.1 6.5 28.2 4.3 4.6 7.1 4.0 1.4 7.9 18.9 12.9 13.7 3.5 5.7 329.3 12.5 13.9 23.1 3.3 2.2 13.1 36.7 6.2 2.7 14.9 5.9 4.6 5.4 1.0 3.9 11.4 8.2 3.0 1.3 9.0 16.9 4.5 7.1 5.2 24.9 21.7 73.6 5.1 0.0 6.2 18.3 6.3 6.1 33.7 18.2 46.1 8.6 794.1 20.3 17.4 FEN1 "FEN-1, MF1, RAD2" ENSG00000168496 "Flap structure-specific endonuclease 1" P39748 11 61792911-61797238 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication" "Endonuclease, Exonuclease, Hydrolase, Nuclease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 46.0" "Cell type enhanced" "Detected in many" "Erythroid cells: 87.5;Extravillous trophoblasts: 70.9;Spermatocytes: 61.0;Spermatogonia: 62.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002262, HPA006748" Enhanced Enhanced Nucleoplasm,Nucleoli NA Yes 160000 "Cluster 44: Non-specific - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Nucleoli "CAB002262: AB_563729, HPA006748: AB_1848494" "unprognostic (1.82e-1)" "unprognostic (2.71e-2)" "unprognostic (3.76e-2)" "unprognostic (2.77e-1)" "unprognostic (1.26e-1)" "unprognostic (6.45e-2)" "prognostic unfavorable (3.39e-6)" "unprognostic (1.50e-2)" "unprognostic (9.82e-2)" "prognostic favorable (7.85e-4)" "unprognostic (2.82e-3)" "unprognostic (5.86e-2)" "prognostic unfavorable (5.73e-6)" "prognostic favorable (9.46e-4)" "unprognostic (1.10e-1)" "unprognostic (4.49e-3)" "unprognostic (4.04e-2)" 5.9 10.4 7.8 21.3 7.8 39.5 10.2 10.9 9.9 6.2 9.6 15.5 11.2 6.3 7.1 14.2 5.7 4.3 6.6 8.0 7.7 5.8 9.9 5.6 34.0 10.0 8.3 3.9 6.8 5.6 8.3 12.9 10.7 6.2 16.1 17.4 6.1 5.9 13.1 9.6 11.4 8.9 6.8 12.8 8.4 19.1 9.1 46.0 4.8 9.6 37.4 8.1 4.9 8.1 154.6 139.7 149.3 81.3 14.9 18.0 94.9 133.3 76.1 160.9 181.4 123.4 112.8 222.6 100.3 57.3 150.5 158.3 214.3 117.7 163.3 117.8 117.6 117.6 187.7 127.3 11.0 184.7 115.4 12.7 15.8 148.1 39.0 23.3 63.1 122.1 181.3 155.1 136.0 195.4 259.7 165.4 165.3 120.3 134.7 173.8 173.7 228.9 64.4 144.7 170.0 140.7 89.6 115.0 79.1 70.1 167.4 127.1 43.2 141.5 178.1 182.3 134.6 120.4 204.3 228.9 98.4 121.9 124.6 24.7 6.7 14.2 16.2 12.9 16.8 14.4 12.3 15.1 8.0 14.8 14.0 13.8 2.7 20.0 12.9 24.5 25.2 10.3 7.8 7.8 10.9 9.9 8.0 7.7 10.0 8.3 10.7 6.8 9.1 8.1 2.7 0.0 2.2 0.3 14.0 10.3 5.2 18.2 7.4 23.8 7.4 7.4 5.8 5.7 7.7 0.0 12.5 53.0 15.9 6.7 7.9 17.3 21.7 4.2 5.5 5.5 4.8 87.5 2.0 12.2 70.9 8.6 7.1 6.3 0.0 18.6 1.1 7.2 25.7 15.2 2.4 8.0 18.3 5.4 6.8 14.4 5.6 6.2 5.4 0.0 12.4 31.3 13.4 1.5 3.1 12.2 9.4 7.2 45.3 6.5 3.7 5.7 6.4 23.3 0.0 6.8 12.2 61.0 62.1 11.3 6.1 30.9 11.0 9.0 22.0 5.2 FFAR4 "GPR120, GPR129, O3FAR1, PGR4" ENSG00000186188 "Free fatty acid receptor 4" Q5NUL3 10 93566665-93604480 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "Differentiation, Inflammatory response" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 11.4;pituitary gland: 11.0" "Cell type enriched" "Detected in some" 4 "Intestinal goblet cells: 125.7" "Cancer enhanced" "Detected in some" "colorectal cancer: 4.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "OE19: 12.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA042563 Uncertain "Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane" "HPA042563: AB_10794762" "unprognostic (1.96e-1)" "unprognostic (1.06e-2)" "unprognostic (1.14e-2)" "unprognostic (4.21e-2)" "unprognostic (2.12e-1)" "unprognostic (4.98e-4)" "unprognostic (1.41e-3)" "unprognostic (1.20e-2)" "unprognostic (2.34e-2)" "unprognostic (7.87e-2)" "unprognostic (9.51e-2)" "unprognostic (1.49e-1)" "unprognostic (3.85e-2)" "unprognostic (5.32e-2)" "unprognostic (2.71e-1)" "unprognostic (1.02e-1)" "unprognostic (1.49e-1)" 4.1 0.4 1.2 0.7 1.3 0.1 1.3 0.6 1.2 0.1 0.3 8.3 0.5 0.0 0.0 0.2 1.0 0.5 0.3 1.0 1.8 0.1 0.4 3.6 0.2 0.6 0.8 0.0 0.6 0.1 11.0 0.1 0.5 0.1 11.4 0.2 0.1 0.0 0.3 0.9 0.6 0.2 0.3 0.1 0.5 1.5 2.6 0.3 0.1 0.1 0.1 0.1 0.0 0.7 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.3 0.0 0.1 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.1 12.9 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.9 0.1 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.2 1.2 1.3 0.6 1.2 1.0 1.8 0.6 0.8 0.5 0.3 2.6 0.7 0.2 0.0 0.5 0.0 0.3 0.0 0.3 0.0 0.0 0.1 0.2 0.8 0.4 7.2 0.6 0.0 0.0 0.2 0.0 28.1 0.0 0.8 27.8 0.1 0.0 0.3 20.9 0.0 3.2 0.0 0.5 0.2 0.0 0.1 0.0 0.0 0.0 0.0 7.4 0.0 2.0 125.7 0.0 7.2 4.4 16.7 0.6 7.6 1.8 3.7 0.5 0.0 0.0 0.0 0.3 0.9 23.0 0.0 0.0 0.3 0.3 0.0 0.0 0.2 0.0 0.5 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 5.9 0.3 FGFR2 "BEK, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25" ENSG00000066468 "Fibroblast growth factor receptor 2" P21802 10 121478332-121598458 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Apoptosis "Heparin-binding, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Craniosynostosis, Disease variant, Ectodermal dysplasia, FDA approved drug targets, Lacrimo-auriculo-dento-digital syndrome, Mental retardation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 273.8;choroid plexus: 198.1" "Group enriched" "Detected in many" 5 "Astrocytes: 228.2;Cholangiocytes: 213.1;Oligodendrocytes: 562.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 24 "basophil: 13.2;eosinophil: 3.8" "Lineage enriched" "Detected in single" 58 "granulocytes: 13.2" "Cell line enhanced" "Detected in many" "AN3-CA: 189.0;BEWO: 60.9;CACO-2: 49.6;HaCaT: 55.6;HAP1: 63.7;NTERA-2: 57.8;T-47d: 49.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010886, HPA035305" Uncertain Supported "Nucleoplasm,Vesicles,Cell Junctions" "Secreted - unknown location" NA NA 1200000 "Cluster 34: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Cell Junctions" "Nucleoplasm, Vesicles" "CAB010886: AB_259379, HPA035305: AB_10672862" "unprognostic (5.53e-2)" "prognostic favorable (8.79e-4)" "unprognostic (1.08e-1)" "unprognostic (5.23e-2)" "unprognostic (1.73e-1)" "prognostic favorable (9.32e-4)" "unprognostic (1.53e-1)" "unprognostic (4.96e-3)" "unprognostic (1.74e-1)" "unprognostic (1.56e-1)" "unprognostic (1.07e-1)" "unprognostic (3.74e-2)" "unprognostic (1.01e-1)" "unprognostic (6.11e-2)" "unprognostic (2.54e-1)" "unprognostic (6.93e-2)" "unprognostic (2.25e-1)" 5.7 21.3 103.9 8.2 186.8 0.3 22.9 178.9 198.9 19.7 198.1 44.8 10.4 54.6 15.3 25.2 29.6 31.3 5.6 109.9 124.7 26.3 41.0 30.9 2.9 250.9 185.9 18.0 31.0 61.0 6.8 15.7 220.5 27.4 21.2 1.2 59.1 54.6 0.5 109.3 12.2 43.6 165.5 0.8 22.5 7.6 148.0 10.1 54.6 0.2 9.1 16.6 27.4 273.8 7.2 0.4 30.2 189.0 0.1 0.0 60.9 0.4 0.0 0.0 0.0 49.6 1.1 0.1 12.5 2.8 0.1 55.6 63.7 13.0 0.0 0.1 12.7 0.0 0.2 1.2 1.5 0.2 11.7 0.1 26.2 0.0 0.6 0.0 0.0 0.3 0.2 0.2 0.0 11.7 0.2 0.1 57.8 8.7 0.0 0.1 0.0 7.5 18.0 15.8 0.5 0.5 0.4 33.4 0.0 36.6 49.3 0.0 0.1 0.3 8.5 0.2 0.7 0.1 0.1 0.0 0.3 0.0 0.5 13.2 0.0 3.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 103.9 186.8 178.9 198.9 109.9 124.7 250.9 185.9 220.5 165.5 148.0 273.8 1.4 19.2 36.0 228.2 0.6 40.1 34.3 18.4 58.6 0.2 8.7 25.4 9.1 213.1 38.4 36.8 0.0 16.5 0.3 7.3 0.0 7.4 4.1 28.1 4.4 1.0 2.4 2.7 14.8 0.2 3.0 9.0 13.3 53.1 0.0 0.1 1.8 5.0 2.3 0.0 31.2 40.8 10.2 0.6 4.4 9.6 1.2 1.1 5.4 10.3 0.6 2.0 1.0 6.0 562.5 0.7 3.0 6.0 0.1 15.0 1.8 13.6 15.3 0.2 0.0 1.6 2.6 0.7 9.9 18.7 27.7 4.0 1.5 0.4 3.8 31.4 FGFRL1 ENSG00000127418 "Fibroblast growth factor receptor like 1" Q8N441 4 1009936-1026898 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 34.0;Granulosa cells: 30.9;Hepatocytes: 37.5;Muller glia cells: 94.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.1;non-classical monocyte: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "U-251 MG: 99.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026019, HPA068828" Approved Supported Vesicles No No "Cluster 7: Monocytes - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 5: Muller glia cells - Visual perception" Vesicles "CAB026019: , HPA068828: AB_2686043" "unprognostic (1.30e-2)" "unprognostic (2.54e-2)" "unprognostic (6.27e-2)" "unprognostic (2.80e-2)" "unprognostic (1.23e-2)" "unprognostic (1.48e-1)" "unprognostic (2.62e-2)" "unprognostic (9.79e-2)" "unprognostic (4.87e-3)" "unprognostic (8.46e-2)" "unprognostic (2.01e-2)" "unprognostic (1.51e-1)" "unprognostic (2.36e-3)" "unprognostic (1.49e-1)" "unprognostic (7.80e-2)" "unprognostic (1.06e-2)" "unprognostic (1.96e-2)" 38.1 56.0 40.8 5.0 43.3 7.6 24.1 40.6 49.5 15.7 29.8 10.2 7.3 9.9 3.4 5.5 36.0 9.3 19.8 39.2 33.5 25.4 52.8 15.1 3.1 49.9 45.8 25.4 71.6 16.1 21.6 3.0 46.5 12.4 4.9 10.5 37.6 2.7 20.6 10.7 13.5 4.0 42.2 9.1 27.2 5.5 47.9 1.4 67.1 9.6 2.2 11.2 8.0 42.1 23.2 31.6 11.3 34.3 11.9 12.3 2.9 40.4 6.2 12.9 8.4 23.1 47.9 2.6 49.3 63.3 58.3 5.8 21.8 14.1 11.8 8.3 21.0 0.3 41.2 61.5 24.0 13.7 5.6 25.7 11.7 22.4 9.5 48.4 12.5 9.3 25.3 8.9 7.9 30.8 16.0 37.7 14.2 39.7 83.8 24.7 16.3 16.7 22.6 3.6 1.2 2.2 38.1 0.8 15.2 13.4 22.5 11.9 26.1 68.8 27.2 35.2 99.8 8.9 12.9 3.8 18.1 15.6 22.8 0.6 0.0 0.0 0.2 1.1 0.0 0.1 0.4 0.0 0.1 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.1 40.8 43.3 40.6 49.5 39.2 33.5 49.9 45.8 46.5 42.2 47.9 42.1 3.8 3.2 4.1 34.0 2.8 6.5 3.7 5.4 2.2 5.4 13.2 6.1 8.5 11.5 6.9 7.3 0.0 1.6 4.1 4.4 0.0 9.6 0.2 6.0 4.2 2.6 1.8 4.8 3.2 10.2 26.6 5.1 6.6 13.5 1.3 30.9 5.3 37.5 3.2 0.0 2.8 11.0 0.0 1.6 2.5 1.2 4.4 3.4 7.2 1.9 1.3 94.0 1.0 5.0 5.4 19.9 2.7 3.4 2.2 11.4 2.9 7.6 7.0 5.6 0.0 3.3 5.1 0.4 4.2 1.2 4.7 1.5 4.2 17.5 3.6 8.8 FIBCD1 FLJ14810 ENSG00000130720 "Fibrinogen C domain containing 1" Q8N539 9 130902438-130939286 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 9.9;brain: 26.7;parathyroid gland: 12.5" "Cell type enhanced" "Detected in some" "Early spermatids: 19.6;Exocrine glandular cells: 30.1;Intestinal goblet cells: 24.5;Ionocytes: 26.4;Late spermatids: 36.1;Pancreatic endocrine cells: 28.6;Spermatogonia: 16.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 6 "non-classical monocyte: 1.1" "Lineage enriched" "Detected in single" 11 "monocytes: 1.1" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 13.7;MCF7: 32.8;OE19: 22.9;RPTEC TERT1: 24.4;THP-1: 12.5;U-2 OS: 14.1;U-251 MG: 13.5" "Group enriched" "Detected in many" 4 "basal ganglia: 17.6;hippocampal formation: 68.4" "Region enriched" "Detected in many" 5 "hippocampal formation: 57.3" HPA055353 Approved Approved "Cell Junctions" NA NA 19000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 10: Brain - Neuronal signaling" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Cell Junctions" "HPA055353: AB_2682791" "unprognostic (1.18e-3)" "unprognostic (2.70e-1)" "unprognostic (4.69e-2)" "unprognostic (5.63e-2)" "unprognostic (9.11e-2)" "unprognostic (1.62e-1)" "unprognostic (4.16e-5)" "unprognostic (1.83e-3)" "unprognostic (3.14e-1)" "unprognostic (1.28e-1)" "unprognostic (2.05e-2)" "unprognostic (4.45e-2)" "unprognostic (1.42e-6)" "unprognostic (1.66e-1)" "unprognostic (5.53e-2)" "unprognostic (6.68e-3)" "unprognostic (2.77e-1)" 0.1 9.9 8.0 0.0 1.8 0.0 0.5 0.0 15.8 0.0 0.0 1.0 0.2 0.0 0.2 0.0 0.0 0.2 0.5 26.7 1.4 0.1 0.0 2.1 0.0 8.3 6.3 0.1 0.0 12.5 0.1 0.9 5.2 0.1 0.7 1.3 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.3 0.1 6.6 5.4 0.0 0.0 0.0 0.0 0.9 0.1 2.7 0.3 3.5 1.2 0.0 0.1 0.0 0.0 5.9 8.7 0.4 1.2 0.0 3.7 0.0 2.3 0.3 6.3 2.0 0.0 0.0 0.1 0.0 0.1 0.0 0.7 0.7 0.4 0.2 0.3 0.0 0.1 3.9 0.0 13.7 0.0 0.0 0.7 0.0 0.0 32.8 0.0 2.8 2.1 22.9 0.6 0.0 5.7 0.4 24.4 0.0 0.2 0.0 1.1 0.1 0.8 0.9 2.0 12.5 0.0 1.3 14.1 0.1 13.5 0.0 0.0 0.0 4.6 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.1 8.0 1.8 0.0 15.8 26.7 1.4 8.3 6.3 5.2 0.0 5.4 2.7 0.2 0.0 0.0 0.3 0.0 0.0 0.9 5.0 0.0 3.2 0.8 0.0 1.3 0.0 2.3 1.8 0.0 11.6 0.0 10.4 0.0 0.3 19.6 0.0 0.1 0.4 0.0 0.0 0.3 30.1 0.9 0.9 0.0 0.0 0.0 0.8 0.0 0.0 1.1 3.3 0.3 24.5 26.4 0.0 0.0 36.1 0.6 0.5 0.0 1.9 0.4 0.6 0.0 0.0 0.1 28.6 6.3 3.4 0.0 0.7 2.5 0.1 2.1 0.2 0.0 0.0 0.8 9.5 16.3 0.0 0.0 4.0 0.0 0.9 6.7 1.5 FITM2 "C20orf142, dJ881L22.2, FIT2" ENSG00000197296 "Fat storage inducing transmembrane protein 2" Q8N6M3 20 44302840-44311202 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid metabolism" Hydrolase "Deafness, Disease variant, Dystonia, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "heart muscle: 67.4" "Cell type enriched" "Detected in many" 9 "Cardiomyocytes: 153.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (2.92e-2)" "unprognostic (7.61e-2)" "unprognostic (2.27e-2)" "unprognostic (2.10e-3)" "unprognostic (1.02e-1)" "unprognostic (3.57e-3)" "unprognostic (1.63e-2)" "unprognostic (3.90e-2)" "unprognostic (8.43e-2)" "unprognostic (5.19e-2)" "unprognostic (6.56e-3)" "unprognostic (1.19e-1)" "prognostic favorable (8.98e-12)" "unprognostic (2.07e-1)" "unprognostic (2.54e-1)" "unprognostic (3.38e-3)" "unprognostic (2.49e-3)" 11.4 11.1 4.8 2.9 5.0 1.2 7.0 5.7 6.3 4.2 5.9 5.2 4.3 4.0 8.7 3.3 3.7 3.2 67.4 4.8 5.9 7.9 6.4 4.1 2.2 6.9 5.9 4.6 7.4 13.6 5.2 1.9 7.4 6.4 6.0 6.7 6.5 4.4 9.2 5.7 3.9 5.3 4.2 2.6 4.6 3.8 5.4 1.7 6.3 16.8 2.6 4.5 3.1 4.7 7.2 10.9 4.5 6.6 31.4 12.8 4.6 11.5 8.4 8.9 4.9 13.5 5.1 4.9 6.5 13.0 14.3 15.8 5.7 7.7 9.6 1.4 2.7 1.6 6.5 22.9 6.6 3.1 4.0 9.7 17.2 6.2 4.7 4.9 6.4 3.1 2.7 14.2 9.1 22.4 1.2 3.4 1.1 10.8 13.9 1.9 8.4 4.9 5.1 6.7 2.7 3.2 24.4 13.5 10.3 2.0 16.5 2.4 7.9 28.2 12.6 16.6 6.8 5.2 14.4 1.3 12.6 4.9 14.4 0.7 1.0 0.6 1.1 1.0 1.2 0.6 1.2 0.9 1.0 0.6 2.0 1.6 0.4 1.4 0.8 0.6 1.2 0.9 4.8 5.0 5.7 6.3 4.8 5.9 6.9 5.9 7.4 4.2 5.4 4.7 2.8 6.4 9.7 1.3 3.6 6.9 3.5 2.8 1.2 6.4 5.0 3.4 153.9 11.5 4.3 5.5 6.2 2.0 1.0 5.1 1.9 5.2 4.6 2.2 5.0 4.4 9.1 0.8 2.3 8.6 3.5 9.4 4.1 2.1 0.0 4.4 8.2 14.1 3.4 6.7 2.1 4.8 0.0 3.8 2.2 1.2 7.8 1.7 7.2 1.0 2.3 6.6 2.1 4.0 0.9 5.7 4.1 7.5 3.1 3.1 5.9 6.2 4.0 5.9 0.0 5.6 6.3 9.1 6.0 2.7 8.1 1.5 2.1 16.3 9.2 2.2 FKBP8 "FKBP38, FKBPr38" ENSG00000105701 "FKBP prolyl isomerase 8" Q14318 19 18531751-18544077 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Host-virus interaction" "Isomerase, Rotamase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 719.1;Late spermatids: 1236.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "eosinophil: 93.4;neutrophil: 78.0" "Lineage enriched" "Detected in all" 5 "granulocytes: 93.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025346, HPA045177" Supported Supported "Endoplasmic reticulum,Mitochondria,Cytosol" NA NA 10000 "Cluster 52: Eosinophils - Transcription" "Cluster 43: Testis - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria "Endoplasmic reticulum, Cytosol" "CAB025346: , HPA045177: AB_2679244" "unprognostic (1.61e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (1.24e-4)" "unprognostic (8.93e-2)" "unprognostic (2.73e-1)" "unprognostic (9.22e-2)" "unprognostic (2.54e-2)" "unprognostic (2.26e-1)" "unprognostic (2.10e-2)" "unprognostic (1.49e-1)" "prognostic favorable (7.76e-4)" "unprognostic (8.51e-2)" "unprognostic (1.61e-1)" "unprognostic (2.97e-1)" "unprognostic (6.89e-2)" "unprognostic (1.12e-2)" "unprognostic (2.32e-1)" 206.9 161.5 426.8 79.8 423.7 272.9 197.3 359.7 645.5 235.3 332.7 311.1 85.5 188.6 59.0 238.3 198.1 85.5 244.3 427.4 395.7 194.8 233.7 187.6 97.9 427.6 405.1 263.6 167.2 109.1 312.3 91.2 406.1 249.4 33.6 51.4 200.0 115.3 202.7 185.9 159.2 62.5 381.7 193.6 189.3 378.4 423.4 86.2 205.9 105.5 52.7 228.3 222.4 437.8 196.3 139.0 106.0 201.7 106.2 165.6 266.8 155.0 163.1 116.5 160.2 133.3 259.1 111.6 245.0 191.7 77.7 104.4 65.0 216.5 31.4 136.6 316.5 105.3 175.4 162.3 183.3 105.5 220.6 217.3 204.8 104.0 65.4 216.1 121.9 213.2 222.4 254.8 102.1 329.1 190.4 313.1 216.3 174.6 200.2 197.8 88.4 387.3 154.9 126.6 117.1 213.2 108.8 87.7 197.5 77.8 104.5 299.4 143.2 143.2 130.3 282.1 120.0 194.6 118.2 130.8 321.5 166.7 130.8 18.1 14.7 93.4 14.2 15.5 13.3 10.2 14.6 16.3 11.1 9.8 11.1 12.6 78.0 8.8 19.0 11.3 15.8 30.1 426.8 423.7 359.7 645.5 427.4 395.7 427.6 405.1 406.1 381.7 423.4 437.8 115.9 9.6 1.1 35.3 115.1 95.3 164.1 118.4 68.3 64.8 110.9 107.4 2.0 115.8 58.0 101.2 14.6 246.4 107.0 287.7 248.4 178.4 412.3 65.6 59.2 92.3 205.9 719.1 32.0 126.9 234.8 126.5 80.5 64.6 52.8 125.0 99.6 66.4 237.3 99.3 33.2 156.8 126.1 184.1 145.0 1236.4 203.8 152.1 202.7 8.4 221.9 149.0 183.4 12.5 32.8 166.9 283.4 165.5 127.2 139.4 339.3 290.4 51.9 56.4 98.6 95.7 129.9 193.5 212.4 96.5 117.9 312.9 145.0 121.7 158.3 158.0 FKRP "FKTR, LGMD2I, MDC1C" ENSG00000181027 "Fukutin related protein" Q9H9S5 19 46746046-46776988 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Transferase "Cardiomyopathy, Congenital muscular dystrophy, Disease variant, Dystroglycanopathy, Limb-girdle muscular dystrophy, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043115, HPA060454" Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" "Secreted to blood" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 17: WM-115 - Nervous system development" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Golgi apparatus, Cytosol" "HPA043115: AB_2678324, HPA060454: AB_2684281" "unprognostic (4.44e-2)" "unprognostic (5.20e-2)" "unprognostic (2.19e-2)" "unprognostic (8.37e-3)" "unprognostic (1.83e-2)" "unprognostic (2.25e-1)" "unprognostic (1.02e-1)" "unprognostic (3.85e-1)" "unprognostic (2.99e-2)" "unprognostic (4.59e-3)" "prognostic favorable (8.98e-4)" "unprognostic (3.53e-1)" "unprognostic (2.30e-2)" "unprognostic (2.53e-1)" "unprognostic (2.46e-1)" "unprognostic (1.01e-1)" "unprognostic (2.53e-2)" 10.5 9.1 8.5 8.1 8.2 8.8 9.9 3.7 11.5 11.4 4.5 13.3 4.8 15.2 5.0 8.8 12.6 6.0 15.8 8.5 10.4 12.0 11.9 10.4 7.4 10.1 7.3 12.7 11.1 7.5 16.8 10.1 8.8 13.5 4.3 5.7 11.1 7.4 19.6 7.2 10.5 5.8 6.1 14.7 10.9 9.3 9.4 5.6 13.6 9.8 4.9 13.0 10.5 8.7 12.7 26.5 17.8 12.5 15.4 16.9 15.8 31.7 21.0 12.6 19.9 17.0 21.4 11.7 17.0 18.2 20.9 13.0 6.6 14.8 11.5 21.9 22.2 11.7 14.4 10.7 13.3 9.3 19.8 19.4 12.5 15.6 15.2 14.6 16.7 6.0 12.2 11.0 12.7 5.8 6.8 22.8 17.2 7.8 6.5 18.3 11.1 4.0 8.0 26.4 12.0 23.1 15.8 7.6 10.6 11.7 8.9 7.3 16.8 18.4 19.8 6.7 25.7 11.6 15.4 11.0 15.0 7.5 25.6 1.3 1.8 0.8 1.5 1.0 0.9 1.7 1.1 1.7 1.1 2.4 1.2 1.6 2.2 2.0 1.1 1.9 0.6 1.2 8.5 8.2 3.7 11.5 8.5 10.4 10.1 7.3 8.8 6.1 9.4 8.7 4.7 9.6 7.4 6.8 3.9 0.8 4.8 3.0 1.2 9.8 5.3 5.2 15.5 4.3 5.6 5.5 6.2 9.6 9.1 4.5 5.9 4.2 12.0 7.9 7.3 6.0 7.8 7.8 6.8 2.4 5.9 6.6 3.6 5.1 1.3 6.7 11.4 16.6 7.6 3.3 8.2 4.2 2.0 10.0 1.2 13.2 5.6 4.3 5.4 3.7 6.1 7.8 2.1 8.0 6.2 4.1 4.7 4.1 3.6 4.3 4.2 8.2 9.7 11.0 6.6 7.2 7.0 12.2 4.0 2.4 1.6 18.7 4.3 4.5 4.0 4.3 FLI1 "EWSR2, SIC-1" ENSG00000151702 "Fli-1 proto-oncogene, ETS transcription factor" Q01543 11 128686535-128813267 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 35.8" "Cell type enhanced" "Detected in many" "B-cells: 65.7;Endothelial cells: 84.2;Hepatic stellate cells: 64.6;Kupffer cells: 86.4;Microglial cells: 231.4;monocytes: 68.4;NK-cells: 93.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 113.9;HUVEC TERT2: 60.5;REH: 49.8;TIME: 63.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065030, HPA073099" Approved Supported "Nucleoplasm,Nuclear bodies" Yes NA "Cluster 10: Basophils - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 36: HEL - Hemostasis" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Nuclear bodies" "HPA065030: , HPA073099: AB_2686572" "unprognostic (1.38e-2)" "unprognostic (7.46e-2)" "unprognostic (6.16e-2)" "unprognostic (3.74e-2)" "unprognostic (6.22e-2)" "unprognostic (4.26e-3)" "unprognostic (1.33e-1)" "unprognostic (8.32e-3)" "unprognostic (2.97e-1)" "unprognostic (9.91e-2)" "unprognostic (1.60e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (4.60e-4)" "unprognostic (4.79e-2)" "unprognostic (2.07e-2)" "unprognostic (2.62e-1)" "unprognostic (4.79e-2)" 10.2 1.9 3.7 10.9 2.3 12.2 6.0 2.1 2.8 5.7 1.2 3.7 3.2 4.6 1.1 2.8 2.7 6.1 6.2 1.8 2.9 2.1 2.8 10.8 12.3 4.7 2.7 1.2 1.7 3.5 0.7 12.5 4.3 1.9 2.9 0.5 2.2 2.2 2.8 1.7 4.0 5.9 3.5 35.8 4.3 0.9 3.9 17.2 2.9 6.6 10.4 6.7 1.9 2.8 0.2 0.0 5.6 0.0 0.8 1.0 0.1 3.3 9.2 3.8 3.1 0.0 0.0 18.5 31.7 11.1 1.1 0.1 0.8 13.5 4.1 9.0 0.2 113.9 0.5 0.0 6.0 13.7 14.6 0.8 1.1 7.7 17.3 11.1 60.5 25.6 0.0 23.3 0.8 0.0 13.3 8.1 1.8 0.0 3.1 49.8 0.1 19.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 5.0 0.0 20.4 63.0 0.7 0.0 0.2 3.5 7.3 16.4 16.6 0.1 31.8 5.2 34.5 15.5 24.5 10.1 15.3 11.9 6.8 8.9 8.2 19.1 6.0 3.7 8.2 11.8 12.3 19.1 3.3 11.1 20.1 3.7 2.3 2.1 2.8 1.8 2.9 4.7 2.7 4.3 3.5 3.9 2.8 53.4 6.4 5.3 0.3 65.7 5.1 0.3 1.7 2.2 0.0 0.7 1.3 5.5 5.7 0.1 1.8 0.0 0.4 43.1 0.0 0.0 0.0 0.5 0.4 0.6 84.2 0.0 23.4 0.3 0.0 0.4 5.9 2.0 0.3 22.8 0.0 64.6 1.3 43.2 0.0 1.5 0.1 0.0 86.4 24.7 0.5 1.8 60.3 7.2 231.4 68.4 0.1 93.7 4.0 0.7 0.0 0.0 0.7 56.9 0.3 0.0 0.4 0.8 0.4 6.6 2.1 3.1 0.2 0.1 0.6 4.1 0.3 52.8 0.9 0.2 0.4 FLRT3 ENSG00000125848 "Fibronectin leucine rich transmembrane protein 3" Q9NZU0 20 14322985-14337614 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Cell adhesion" "Developmental protein" "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 23.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 218.0;Alveolar cells type 2: 156.5;Basal prostatic cells: 168.3;Club cells: 73.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 27.5;hTCEpi: 51.3;RPTEC TERT1: 17.3;WM-115: 62.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056033 Enhanced Supported "Plasma membrane,Cell Junctions,Cytosol" "Intracellular and membrane" NA NA 1100000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" "Cell Junctions, Cytosol" "HPA056033: AB_2683016" "unprognostic (2.14e-1)" "unprognostic (2.57e-1)" "unprognostic (2.98e-1)" "unprognostic (1.14e-3)" "unprognostic (2.30e-1)" "unprognostic (6.00e-2)" "unprognostic (1.63e-1)" "prognostic unfavorable (9.85e-5)" "unprognostic (1.24e-1)" "unprognostic (1.81e-1)" "prognostic unfavorable (1.54e-4)" "unprognostic (3.05e-1)" "prognostic favorable (1.49e-7)" "unprognostic (1.54e-2)" "unprognostic (2.48e-1)" "unprognostic (3.07e-3)" "unprognostic (3.65e-1)" 5.0 3.7 2.3 0.8 3.0 0.0 2.3 6.4 5.3 3.2 0.9 1.6 11.8 2.3 3.1 1.6 2.4 5.0 0.6 5.3 1.3 23.2 7.0 17.7 0.1 0.0 1.3 10.6 1.2 8.2 1.0 1.8 0.8 8.2 0.8 1.6 1.2 14.0 2.0 6.3 2.3 1.4 0.6 0.7 9.7 1.2 2.3 7.3 5.2 0.7 0.3 7.9 2.1 1.8 0.0 12.2 27.5 0.0 0.0 0.0 0.0 2.7 0.8 0.1 0.0 15.3 5.6 0.0 0.9 0.6 0.0 8.0 0.0 8.3 0.1 0.0 1.8 0.0 0.4 0.3 2.4 0.0 0.0 4.6 51.3 0.0 9.7 0.0 0.1 0.2 0.0 0.2 5.3 0.4 3.7 0.0 8.9 6.2 0.1 0.1 0.2 0.0 17.3 3.6 0.5 5.7 0.0 0.0 9.2 15.5 0.5 0.0 0.0 0.0 1.8 0.1 0.7 0.0 0.0 0.0 0.2 0.0 62.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 3.0 6.4 5.3 5.3 1.3 0.0 1.3 0.8 0.6 2.3 1.8 0.3 218.0 156.5 2.3 0.5 8.7 168.3 26.1 55.8 23.9 4.4 6.5 1.2 24.3 73.1 22.0 6.2 0.5 0.0 2.2 13.7 23.6 0.2 0.7 1.7 1.9 11.3 0.0 27.2 14.9 0.0 8.7 37.8 0.7 5.1 5.0 2.9 8.5 0.2 6.7 39.3 2.5 2.0 0.3 0.7 0.5 3.7 1.3 5.4 1.9 1.6 0.6 0.0 26.2 3.9 10.0 3.0 0.4 0.1 24.9 3.5 49.2 13.4 3.3 0.0 25.0 1.8 0.0 0.1 5.9 16.6 0.0 0.8 1.4 1.5 18.3 FMO5 ENSG00000131781 "Flavin containing dimethylaniline monoxygenase 5" P49326 1 147175351-147243050 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 683.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 64.2;Cholangiocytes: 133.0;Hepatocytes: 265.4;Proximal enterocytes: 108.8;Proximal tubular cells: 69.2" "Cancer enriched" "Detected in many" 7 "liver cancer: 43.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 4 "Hep G2: 41.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012373 Enhanced Supported "Endoplasmic reticulum,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Endoplasmic reticulum, Cytosol" "HPA012373: AB_1848975" "unprognostic (2.70e-1)" "unprognostic (1.28e-1)" "unprognostic (1.33e-1)" "unprognostic (2.06e-2)" "unprognostic (1.39e-1)" "unprognostic (3.96e-2)" "unprognostic (2.43e-2)" "unprognostic (2.94e-2)" "unprognostic (1.10e-1)" "unprognostic (1.85e-2)" "unprognostic (2.93e-1)" "unprognostic (1.13e-1)" "prognostic favorable (1.34e-6)" "unprognostic (3.77e-1)" "unprognostic (1.38e-1)" "unprognostic (1.85e-1)" "unprognostic (4.11e-2)" 3.1 5.7 2.0 5.1 2.9 2.0 46.1 3.9 2.8 7.8 0.5 41.3 71.3 2.8 6.9 1.2 3.6 15.8 3.1 2.1 2.4 51.5 683.3 27.1 4.0 4.2 2.9 4.1 48.1 68.3 6.7 2.4 4.8 9.7 46.6 0.9 32.7 4.0 0.8 11.6 73.9 3.5 3.2 4.0 120.1 5.2 3.1 1.1 2.0 1.4 2.5 3.9 1.5 5.6 0.1 1.1 0.6 0.1 2.8 0.8 0.9 0.7 0.5 0.3 0.8 0.7 2.4 0.4 0.8 0.8 0.2 0.4 0.0 0.0 0.0 1.4 0.2 1.6 0.1 41.7 0.9 1.4 9.0 1.3 0.2 0.4 0.0 0.4 0.6 0.2 0.1 0.1 1.5 1.4 0.2 0.7 2.8 5.3 0.8 0.4 0.5 0.4 3.4 0.6 0.5 0.3 0.9 2.8 1.3 1.3 2.1 10.4 1.1 0.0 0.3 0.9 0.0 0.3 0.0 0.3 1.1 0.5 0.3 7.0 12.9 4.1 2.0 5.9 0.3 4.7 0.5 0.6 5.4 8.5 0.3 1.3 1.3 1.2 1.8 2.5 1.6 3.9 2.0 2.9 3.9 2.8 2.1 2.4 4.2 2.9 4.8 3.2 3.1 5.6 2.8 9.6 64.2 11.1 6.4 1.7 3.9 0.9 1.8 2.0 17.5 6.7 1.9 133.0 10.4 14.7 0.0 1.5 1.7 60.8 7.9 7.5 7.7 2.5 1.8 2.7 6.7 4.8 8.2 5.9 1.1 2.9 24.5 6.1 5.7 9.8 5.0 265.4 4.0 3.3 6.4 34.4 4.1 10.0 2.3 4.5 2.8 4.6 28.4 10.3 5.3 0.2 4.1 10.1 17.5 7.0 29.0 1.5 0.4 5.6 108.8 69.2 18.1 1.3 0.0 2.2 1.0 5.9 0.9 1.3 1.6 1.4 2.6 6.6 20.7 6.4 FNDC11 "C20orf195, MGC5356" ENSG00000125531 "Fibronectin type III domain containing 11" Q9BVV2 20 63547891-63556695 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 45 "testis: 108.0" "Cell type enhanced" "Detected in some" "Club cells: 1.3;Collecting duct cells: 1.8;Endometrial ciliated cells: 5.1;Respiratory ciliated cells: 6.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 5 "memory B-cell: 1.5;naive B-cell: 3.3" "Lineage enriched" "Detected in single" 7 "B-cells: 3.3" "Cell line enhanced" "Detected in some" "CAPAN-2: 5.2;EFO-21: 2.6;HaCaT: 1.5;OE19: 1.8;SH-SY5Y: 3.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA041341 Approved Nucleoplasm,Vesicles,Aggresome NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 83: Testis - Spermatogenesis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Vesicles" Aggresome "HPA041341: AB_10794991" "unprognostic (2.01e-1)" "unprognostic (6.63e-2)" "unprognostic (6.06e-2)" "unprognostic (1.26e-1)" "unprognostic (1.51e-2)" "unprognostic (1.15e-1)" "unprognostic (2.36e-1)" "unprognostic (9.99e-3)" "unprognostic (7.94e-2)" "unprognostic (8.30e-4)" "unprognostic (3.68e-1)" "unprognostic (8.33e-2)" "unprognostic (3.56e-2)" "unprognostic (1.18e-1)" "unprognostic (1.05e-1)" "unprognostic (3.75e-1)" "unprognostic (6.81e-2)" 0.4 0.1 0.2 0.3 0.1 0.5 0.6 0.1 0.3 0.8 0.3 0.3 0.1 0.4 2.3 0.2 1.2 0.3 0.2 0.1 1.1 1.2 0.1 0.9 0.6 0.5 0.5 0.4 0.1 0.0 0.9 0.1 0.3 0.6 0.0 0.0 0.4 0.1 0.1 0.4 0.6 0.0 0.4 1.0 0.4 108.0 0.5 0.3 0.5 0.0 0.4 0.7 0.6 0.2 0.2 0.0 0.9 0.0 0.1 0.0 0.0 0.2 0.3 0.0 0.0 0.0 5.2 0.3 2.6 0.0 0.1 1.5 0.1 0.1 0.0 0.0 0.0 0.1 0.4 0.0 0.1 0.0 0.6 0.0 0.1 0.4 0.0 0.0 0.5 0.0 0.4 0.0 0.0 0.5 0.0 0.1 0.1 1.8 0.4 0.0 0.0 0.0 0.9 0.0 0.2 3.3 0.0 0.0 0.1 0.2 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.5 0.0 0.0 0.0 1.5 0.1 0.2 0.0 3.3 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.2 0.1 0.1 0.3 0.1 1.1 0.5 0.5 0.3 0.4 0.5 0.2 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.7 1.0 0.0 0.0 1.3 1.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 5.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.2 6.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 FNDC8 DKFZp434H2215 ENSG00000073598 "Fibronectin type III domain containing 8" Q8TC99 17 35121615-35130732 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 474 "testis: 89.0" "Group enriched" "Detected in some" 73 "Early spermatids: 592.7;Late spermatids: 2294.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 1.3;JURKAT: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA026521, HPA059803" Supported Approved Cytosol NA NA "Cluster 24: B-cells - Unknown function" "Cluster 36: Testis - Spermatogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "HPA026521: AB_2106163, HPA059803: " "unprognostic (1.45e-1)" "unprognostic (6.58e-2)" "unprognostic (2.32e-1)" "unprognostic (1.17e-1)" "unprognostic (1.25e-2)" "unprognostic (2.10e-1)" "unprognostic (5.88e-2)" "unprognostic (1.91e-1)" "unprognostic (2.02e-1)" "unprognostic (1.70e-1)" "unprognostic (8.43e-2)" "unprognostic (3.48e-3)" "unprognostic (9.02e-2)" "unprognostic (6.41e-3)" "unprognostic (1.09e-2)" "unprognostic (1.47e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 89.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.3 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.2 0.4 0.0 0.1 0.5 0.3 0.1 0.0 0.1 0.7 0.3 0.7 0.0 0.2 0.1 0.2 0.2 0.1 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.2 0.5 0.7 0.7 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.4 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 592.7 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2294.8 7.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.1 0.0 0.0 19.7 0.0 0.0 7.9 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FOXG1 "BF1, FKH2, FKHL1, FKHL2, FKHL3, FKHL4, FOXG1A, FOXG1B, FOXG1C, HBF-3, HFK1, HFK2, HFK3, QIN" ENSG00000176165 "Forkhead box G1" P55316 14 28766787-28770277 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 25.3" "Cell type enhanced" "Detected in some" "Astrocytes: 69.5;Excitatory neurons: 35.9;Inhibitory neurons: 33.2;Oligodendrocyte precursor cells: 31.2;Spermatocytes: 15.4" "Cancer enriched" "Detected in some" 10 "glioma: 15.9" "Group enriched" "Detected in many" 37 "amygdala: 11.6;basal ganglia: 20.1;cerebral cortex: 25.3;hippocampal formation: 21.5;white matter: 8.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 15.6;SCLC-21H: 39.0;U-138 MG: 25.2;U-251 MG: 25.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 10: Non-specific - Unknown function" "unprognostic (2.92e-2)" "unprognostic (2.22e-1)" "unprognostic (1.92e-1)" "unprognostic (3.49e-1)" "unprognostic (1.17e-3)" "unprognostic (2.14e-2)" "unprognostic (1.27e-11)" "unprognostic (4.10e-2)" "unprognostic (1.08e-1)" "unprognostic (1.60e-2)" 0.0 0.0 11.6 0.0 20.1 0.0 0.0 0.0 25.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 21.5 0.4 0.0 0.0 0.0 0.6 0.0 0.0 0.4 0.0 0.1 2.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.2 3.1 0.2 0.0 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 7.6 6.0 4.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.0 0.0 3.4 0.0 0.0 0.0 15.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 9.0 0.1 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.0 0.0 0.0 0.1 0.0 2.3 0.0 0.1 0.1 25.2 0.0 2.0 25.2 0.0 0.0 0.0 8.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.6 20.1 0.0 25.3 21.5 0.4 0.0 0.0 0.0 0.0 0.2 8.9 0.0 0.0 0.0 69.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.8 0.0 0.2 0.0 2.1 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.1 0.0 0.0 35.9 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 33.2 0.0 0.0 0.0 0.0 3.4 0.3 0.0 0.0 4.7 0.0 1.4 0.0 31.2 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 9.5 15.4 2.4 0.1 0.0 0.1 0.0 0.0 0.0 0.0 FOXI3 ENSG00000214336 "Forkhead box I3" A8MTJ6 2 88446787-88452693 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "placenta: 5.2;retina: 2.0" "Group enriched" "Detected in some" 5 "Cytotrophoblasts: 3.3;Muller glia cells: 6.4;Syncytiotrophoblasts: 2.7" "Cancer enriched" "Detected in some" 5 "testis cancer: 10.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "BEWO: 43.2;SuSa: 55.0" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "unprognostic (2.72e-1)" "unprognostic (1.20e-1)" "unprognostic (2.92e-1)" "unprognostic (6.72e-4)" "unprognostic (8.11e-3)" "unprognostic (1.36e-1)" "unprognostic (6.58e-2)" "unprognostic (5.29e-2)" "unprognostic (1.15e-1)" 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 5.2 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 43.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.1 10.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 2.5 0.0 0.0 0.0 55.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.5 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 2.7 0.0 0.0 0.0 0.0 FOXL3 ENSG00000248767 "Forkhead box L3" A0A1W2PRP0 7 290170-294422 "Predicted intracellular proteins" Transcription DNA-binding "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 8 "testis: 2.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 78: Testis - Spermatogenesis" 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.1 0.1 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FRAT2 ENSG00000181274 "FRAT regulator of WNT signaling pathway 2" O75474 10 97332497-97334729 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in all" 4 "testis cancer: 70.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "eosinophil: 15.0;neutrophil: 58.2" "Lineage enriched" "Detected in all" 7 "granulocytes: 58.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049763 Uncertain Approved Nucleoplasm,Mitochondria No No "Cluster 9: Neutrophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: U-937 - Innate immune response" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Mitochondria "HPA049763: AB_2680868" "unprognostic (4.93e-2)" "unprognostic (1.28e-2)" "unprognostic (2.13e-1)" "unprognostic (1.46e-1)" "unprognostic (4.04e-3)" "unprognostic (1.87e-2)" "prognostic unfavorable (3.02e-4)" "unprognostic (3.17e-3)" "unprognostic (2.60e-1)" "unprognostic (8.02e-2)" "unprognostic (4.60e-2)" "unprognostic (3.25e-2)" "prognostic favorable (2.55e-4)" "unprognostic (7.87e-3)" "unprognostic (4.83e-2)" "unprognostic (2.34e-1)" "unprognostic (9.08e-2)" 5.3 3.6 7.2 10.4 7.1 31.0 8.0 7.7 7.4 6.0 9.8 17.1 25.1 4.1 6.2 14.4 7.1 4.0 6.0 6.3 6.8 7.8 18.3 9.7 8.7 7.7 7.6 2.8 14.0 5.2 3.0 7.4 6.8 7.9 15.5 3.3 15.1 4.3 10.1 20.4 15.9 4.1 7.0 28.9 13.2 14.6 7.5 8.9 5.3 9.1 10.8 6.7 8.1 6.0 10.9 4.3 6.9 31.2 4.9 4.0 25.7 2.4 8.9 3.7 3.7 6.8 12.5 13.3 8.4 2.5 2.2 20.3 18.3 9.5 2.9 20.0 28.0 17.9 9.2 15.0 2.8 28.9 20.6 3.2 20.0 3.6 11.4 7.9 9.3 11.7 15.8 4.2 1.8 17.9 12.6 36.5 42.9 36.2 17.5 12.8 2.9 19.1 8.9 9.8 12.5 10.2 3.1 19.1 12.6 28.0 28.8 44.8 4.2 2.2 2.7 1.7 6.4 11.4 12.5 6.6 2.6 49.3 0.8 8.3 7.2 15.0 1.1 4.8 0.6 1.1 1.3 1.8 3.8 3.2 2.2 1.3 58.2 1.6 7.9 1.0 0.7 2.3 7.2 7.1 7.7 7.4 6.3 6.8 7.7 7.6 6.8 7.0 7.5 6.0 18.2 0.0 3.9 2.9 15.7 31.7 25.3 6.6 46.1 19.7 24.7 19.6 6.4 20.0 5.0 14.7 4.2 6.1 26.1 31.0 11.7 2.2 40.7 39.6 9.7 10.3 13.8 14.5 2.0 5.3 18.5 6.4 37.2 46.3 1.3 16.7 8.6 11.3 8.6 11.8 2.8 30.6 4.1 28.3 9.0 42.3 2.1 25.2 10.6 7.5 24.7 5.0 14.4 2.0 1.1 3.4 21.6 2.6 8.4 30.0 13.5 3.7 4.5 18.1 0.0 14.9 8.7 2.3 4.4 37.7 52.7 7.8 18.8 20.1 31.6 32.3 FRMD8 "FKSG44, FLJ90369, iTAP" ENSG00000126391 "FERM domain containing 8" Q9BZ67 11 65386621-65413525 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Suprabasal keratinocytes: 83.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "WM-115: 129.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002861 Approved Approved "Nucleoplasm,Plasma membrane,Centriolar satellite,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 71: Testis - DNA repair" "Cluster 17: WM-115 - Nervous system development" "Cluster 28: Keratinocytes - Keratinization" "Plasma membrane, Centriolar satellite" "Nucleoplasm, Cytosol" "HPA002861: AB_1078878" "unprognostic (1.54e-1)" "unprognostic (4.07e-1)" "unprognostic (6.28e-2)" "unprognostic (1.73e-2)" "unprognostic (1.03e-1)" "unprognostic (1.17e-1)" "prognostic unfavorable (9.94e-5)" "unprognostic (9.12e-3)" "unprognostic (1.51e-2)" "unprognostic (6.36e-3)" "unprognostic (1.90e-2)" "unprognostic (6.41e-3)" "unprognostic (4.19e-3)" "unprognostic (1.47e-2)" "unprognostic (7.36e-3)" "unprognostic (3.34e-1)" "unprognostic (2.91e-2)" 19.8 17.5 9.6 11.8 11.0 13.0 19.7 12.2 14.5 20.8 9.1 15.0 11.7 14.6 5.3 37.3 15.8 11.6 17.1 13.1 7.9 19.7 13.4 23.5 15.6 12.9 11.3 12.2 23.0 4.0 11.6 10.4 11.4 15.8 6.7 1.7 18.0 6.5 14.8 34.0 23.8 6.6 9.5 40.8 13.4 18.0 11.5 11.1 17.8 5.1 13.6 14.6 26.4 16.2 17.8 22.1 8.7 20.4 23.0 12.0 15.6 20.1 18.1 16.7 12.7 21.2 28.5 21.9 41.9 27.6 11.6 30.3 11.3 16.9 7.0 38.8 10.6 29.9 21.5 11.7 12.4 16.9 44.8 14.9 13.2 15.7 8.2 8.9 26.6 23.2 25.5 23.5 18.3 23.9 26.6 24.6 10.2 13.0 28.7 33.7 16.6 25.2 13.5 21.8 18.9 14.0 15.0 60.1 47.7 7.7 22.0 13.7 23.6 18.4 19.7 26.1 12.3 41.0 22.5 20.4 16.0 10.7 129.8 1.1 12.4 17.7 13.1 13.2 14.1 12.5 9.6 16.7 11.3 9.6 8.8 9.8 23.0 8.2 19.6 13.4 10.8 12.3 9.6 11.0 12.2 14.5 13.1 7.9 12.9 11.3 11.4 9.5 11.5 16.2 30.3 3.2 5.8 2.0 20.5 54.3 22.5 17.7 6.2 5.4 15.4 12.6 7.4 12.8 13.8 12.9 0.0 6.4 25.8 29.3 7.9 21.0 22.3 20.1 12.1 24.8 13.1 24.0 13.4 29.1 15.5 13.0 10.7 23.1 14.0 27.3 37.5 11.0 16.0 5.0 4.9 20.5 8.2 20.2 68.7 4.6 6.2 18.7 19.6 10.3 21.6 4.3 18.6 5.0 10.3 33.8 14.0 7.2 11.9 28.1 32.8 4.6 14.3 4.5 6.6 11.4 14.4 5.3 9.6 24.9 83.5 11.4 21.9 35.2 14.6 35.7 FSTL3 "FLRG, FSRP" ENSG00000070404 "Follistatin like 3" O95633 19 676392-683392 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Osteogenesis, Transcription, Transcription regulation" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Extravillous trophoblasts: 3647.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "BEWO: 164.7;hTCEpi: 181.2;SiHa: 341.5;U-2197: 173.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB024899, HPA045378" Approved Supported Nucleoplasm "Secreted in other tissues" NA Yes 7000000 "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 20: HeLa - Mitochondria" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "CAB024899: , HPA045378: AB_2679300" "unprognostic (9.86e-3)" "unprognostic (1.32e-3)" "prognostic unfavorable (3.01e-4)" "prognostic unfavorable (3.03e-4)" "unprognostic (2.19e-3)" "unprognostic (1.51e-3)" "unprognostic (8.64e-3)" "prognostic unfavorable (4.61e-7)" "unprognostic (9.50e-2)" "prognostic unfavorable (1.65e-4)" "unprognostic (3.50e-2)" "unprognostic (5.91e-2)" "unprognostic (1.03e-3)" "unprognostic (7.22e-3)" "unprognostic (3.07e-1)" "unprognostic (3.75e-1)" "unprognostic (5.89e-3)" 82.9 163.3 16.6 24.1 15.3 13.3 62.4 13.3 19.8 75.6 16.0 82.7 7.7 62.0 6.1 22.0 70.2 16.5 124.1 16.4 17.3 55.9 26.2 132.7 5.5 22.6 16.0 63.8 49.3 3.2 28.9 179.4 17.9 74.9 5.9 2.4 21.1 22.1 11.7 32.3 36.5 42.4 16.7 22.6 43.2 75.2 18.1 2.3 37.9 4.9 1.6 70.5 63.1 18.9 9.5 74.0 5.1 3.7 22.3 56.4 164.7 126.1 18.5 30.7 11.3 27.1 14.4 4.1 49.4 84.7 17.6 65.2 4.1 106.4 10.1 7.8 8.7 3.5 110.2 22.4 95.6 6.7 12.0 70.7 181.2 34.0 140.2 79.3 5.5 3.9 8.2 5.3 46.7 33.1 2.4 4.0 6.2 62.0 26.2 7.2 3.4 8.7 43.1 1.7 3.3 5.7 341.5 6.9 4.3 6.4 6.2 3.5 75.5 30.6 106.6 173.4 46.9 8.5 4.4 2.3 4.7 20.0 14.2 0.0 1.9 0.0 0.4 1.8 0.0 0.1 0.6 0.4 0.9 0.3 1.0 0.6 0.0 0.2 1.4 0.3 0.0 0.9 16.6 15.3 13.3 19.8 16.4 17.3 22.6 16.0 17.9 16.7 18.1 18.9 4.6 19.2 1.9 40.5 1.5 14.5 31.0 11.7 1.8 1.3 11.3 7.9 16.7 32.9 4.4 9.2 0.0 53.9 1.0 1.1 7.9 86.1 8.8 6.4 14.8 8.7 1.2 1.7 9.8 64.3 3647.6 59.6 2.0 18.3 0.0 5.7 16.4 1.9 77.1 3.3 8.4 1.0 0.0 3.7 4.8 7.6 61.2 7.4 5.4 2.8 10.6 6.6 1.0 6.0 5.5 306.5 0.2 26.7 1.0 78.0 1.2 17.7 3.1 1.1 46.0 22.4 57.0 4.6 5.6 4.3 7.7 792.0 2.0 3.6 2.5 30.7 FUCA1 ENSG00000179163 "Alpha-L-fucosidase 1" P04066 1 23845077-23868290 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 181.7;Distal enterocytes: 226.6;Paneth cells: 221.0;Proximal enterocytes: 210.9;Syncytiotrophoblasts: 200.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 165.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046542, HPA056371" Enhanced Supported Vesicles "Intracellular and membrane" NA NA 60000000 "Cluster 14: Monocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA046542: AB_2679691, HPA056371: AB_2683108" "unprognostic (6.94e-3)" "unprognostic (6.53e-2)" "unprognostic (2.68e-3)" "prognostic favorable (2.45e-4)" "unprognostic (5.64e-3)" "unprognostic (2.59e-3)" "unprognostic (1.56e-2)" "unprognostic (1.79e-3)" "unprognostic (4.99e-1)" "unprognostic (2.18e-2)" "unprognostic (2.05e-1)" "unprognostic (4.23e-2)" "prognostic favorable (5.70e-13)" "unprognostic (3.75e-2)" "unprognostic (4.35e-2)" "unprognostic (1.54e-2)" "unprognostic (2.13e-3)" 34.2 34.4 8.3 49.8 8.2 7.7 26.3 8.3 11.2 54.5 23.8 124.2 90.3 20.7 113.0 17.0 51.1 46.6 20.6 8.3 10.5 78.2 104.8 55.1 168.2 9.5 8.8 23.8 23.9 56.9 17.6 72.6 9.6 50.2 140.7 5.7 40.8 60.4 15.8 14.9 81.3 26.7 9.3 71.8 63.9 27.7 10.8 26.8 70.6 17.7 94.1 74.9 13.2 12.8 15.9 10.6 2.2 31.9 4.2 0.3 11.0 16.6 34.4 17.1 31.6 14.5 165.1 23.9 40.9 21.3 18.8 9.4 15.3 35.4 22.4 16.9 25.6 19.7 9.2 32.7 14.2 2.0 62.7 15.3 19.7 6.2 8.1 55.2 6.9 13.3 9.3 0.5 20.6 17.5 5.0 17.7 5.4 48.1 16.9 26.9 0.2 26.2 63.5 40.5 10.9 10.6 47.9 18.5 26.2 17.9 13.6 7.8 1.8 5.8 9.0 38.9 5.6 28.5 31.0 8.5 14.5 58.9 9.5 54.8 100.4 51.9 27.2 99.9 23.1 23.8 19.5 22.9 44.0 14.1 18.9 22.0 12.8 44.6 91.1 25.4 21.4 64.8 8.3 8.2 8.3 11.2 8.3 10.5 9.5 8.8 9.6 9.3 10.8 12.8 12.9 25.6 28.6 4.2 10.5 3.6 27.4 99.3 6.8 4.4 22.2 10.4 5.6 40.0 77.8 84.6 0.0 181.7 13.9 226.6 15.6 64.1 61.0 31.5 2.8 11.6 10.8 20.6 5.8 50.3 24.2 16.7 33.1 13.3 8.2 11.1 25.7 42.7 156.4 0.0 6.3 44.4 44.7 121.0 13.5 24.4 23.3 85.4 8.8 2.8 29.6 13.0 10.3 4.0 4.7 34.9 221.0 19.5 8.7 23.6 210.9 40.2 53.7 5.0 6.6 16.7 13.2 109.0 24.8 8.5 2.8 200.6 11.2 34.6 79.5 40.3 FUZ "CPLANE3, FLJ22688, Fy" ENSG00000010361 "Fuzzy planar cell polarity protein" Q9BT04 19 49806866-49817376 "Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation, Protein transport, Transport" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 78.7" "Group enriched" "Detected in many" 18 "Early spermatids: 1243.5;Late spermatids: 2329.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041779, HPA042196" Approved Approved Cytosol No NA "Cluster 5: Granulocytes - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "HPA041779: AB_10793974, HPA042196: AB_10797383" "unprognostic (2.40e-3)" "unprognostic (1.31e-1)" "unprognostic (7.73e-2)" "unprognostic (2.13e-1)" "unprognostic (1.49e-2)" "unprognostic (1.18e-2)" "unprognostic (4.36e-3)" "unprognostic (9.67e-2)" "unprognostic (1.47e-1)" "unprognostic (1.97e-2)" "unprognostic (1.06e-2)" "unprognostic (1.80e-1)" "prognostic favorable (1.50e-5)" "unprognostic (1.26e-2)" "unprognostic (2.03e-1)" "unprognostic (1.54e-1)" "unprognostic (1.70e-1)" 9.3 17.6 17.3 2.8 21.0 6.2 9.3 18.8 20.8 11.2 19.7 12.1 4.2 11.1 7.3 6.8 19.5 5.2 13.6 16.4 16.8 16.8 7.1 7.7 4.6 19.9 19.1 15.4 12.3 7.1 12.5 4.0 18.2 11.2 1.9 4.9 7.5 7.3 20.4 6.6 6.9 4.1 19.5 8.8 10.2 78.7 18.7 6.0 11.5 12.4 2.2 9.0 8.2 20.4 0.1 10.6 9.5 12.2 8.9 9.5 2.7 5.2 5.4 7.9 11.0 0.9 17.2 3.1 10.6 4.9 2.5 4.3 2.7 9.2 3.5 11.7 20.5 13.0 7.6 0.0 10.1 7.6 7.0 10.1 6.3 16.1 4.0 6.2 7.5 18.6 3.0 8.7 4.1 0.5 14.1 15.4 15.7 8.4 6.3 24.4 7.7 7.4 9.7 2.7 26.5 31.0 1.0 10.8 17.9 3.7 6.2 4.7 3.7 6.6 5.9 1.9 1.9 24.9 26.5 8.4 7.6 0.2 8.4 7.0 4.6 17.7 4.9 2.2 4.1 5.3 3.1 4.2 3.8 6.0 3.8 4.3 10.6 3.8 1.6 15.0 3.8 2.6 17.3 21.0 18.8 20.8 16.4 16.8 19.9 19.1 18.2 19.5 18.7 20.4 9.2 0.0 2.8 6.2 8.4 3.8 19.3 10.1 8.6 7.2 14.5 14.6 3.9 17.2 7.3 7.3 4.2 17.5 12.2 1.9 66.5 15.3 1243.5 61.6 8.0 6.5 2.4 19.3 2.7 5.1 12.1 11.1 6.1 8.1 10.2 11.5 13.6 5.8 13.2 10.1 3.0 3.5 12.2 7.1 7.6 2329.6 27.7 6.7 0.0 2.8 7.9 26.1 5.2 2.0 9.9 4.5 6.1 17.7 10.9 8.0 7.3 86.1 35.4 11.3 0.0 17.1 9.9 95.3 13.5 5.0 4.1 12.0 6.4 13.7 5.5 14.1 GABBR2 "GABABR2, GPR51, GPRC3B, HG20" ENSG00000136928 "Gamma-aminobutyric acid type B receptor subunit 2" O75899 9 98288109-98708935 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, Epilepsy, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "brain: 90.4" "Group enriched" "Detected in some" 4 "Excitatory neurons: 386.5;Inhibitory neurons: 395.1" "Group enriched" "Detected in many" 10 "glioma: 7.2;thyroid cancer: 11.6;urothelial cancer: 3.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 14.6;fHDF/TERT166: 7.3;HUVEC TERT2: 29.5;U-138 MG: 11.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013820, HPA031684, CAB079065" Enhanced Approved NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB079065: , HPA013820: AB_1849364, HPA031684: AB_2673993" "unprognostic (2.00e-1)" "unprognostic (7.56e-2)" "unprognostic (3.75e-1)" "unprognostic (3.09e-5)" "unprognostic (2.52e-1)" "unprognostic (1.16e-1)" "unprognostic (2.81e-2)" "unprognostic (1.42e-1)" "unprognostic (2.66e-1)" "unprognostic (4.43e-2)" "unprognostic (1.43e-2)" "unprognostic (2.06e-1)" "unprognostic (1.76e-2)" "unprognostic (3.52e-2)" "unprognostic (1.91e-1)" "unprognostic (2.68e-2)" "unprognostic (3.45e-2)" 0.0 3.6 26.0 0.2 40.8 0.0 0.0 10.6 90.4 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.6 39.9 18.0 0.0 0.0 0.3 0.0 12.7 19.6 0.0 0.1 0.2 0.6 0.1 12.5 0.0 0.0 8.5 0.0 0.1 2.8 0.2 0.0 0.1 8.3 0.0 0.2 0.6 39.5 0.0 1.4 0.5 0.2 0.5 0.0 36.3 0.0 0.0 0.0 0.0 0.1 0.1 1.2 14.6 2.9 3.0 5.5 0.1 0.1 0.0 0.9 7.3 0.6 0.0 0.1 0.2 1.0 0.0 0.5 0.0 0.0 0.0 1.3 0.0 0.0 0.4 0.0 0.9 0.2 0.0 29.5 0.0 0.3 0.1 0.0 0.4 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 4.0 0.0 0.1 3.5 0.0 0.0 0.0 0.1 1.2 11.5 0.7 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 26.0 40.8 10.6 90.4 39.9 18.0 12.7 19.6 12.5 8.3 39.5 36.3 0.1 0.0 0.0 14.0 0.0 0.1 0.0 0.0 0.0 86.4 0.5 0.1 1.9 0.0 0.1 0.0 0.0 0.5 0.0 0.1 0.0 0.0 90.3 0.1 0.0 0.6 0.0 0.0 386.5 0.2 1.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 395.1 0.0 0.0 0.0 0.0 34.5 0.3 0.1 1.8 11.2 0.0 1.8 0.0 26.2 7.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 7.4 0.0 0.3 1.3 0.7 0.9 0.0 0.1 0.4 0.0 0.3 0.1 0.0 GABRA3 ENSG00000011677 "Gamma-aminobutyric acid type A receptor subunit alpha3" P34903 X 152166234-152451315 "FDA approved drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 15.5;choroid plexus: 16.3;retina: 9.0" "Cell type enhanced" "Detected in some" "Excitatory neurons: 70.3;Hofbauer cells: 16.2;Inhibitory neurons: 22.2;Oligodendrocyte precursor cells: 58.3" "Cancer enriched" "Detected in many" 7 "testis cancer: 16.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 9.9;HMC-1: 8.4;Karpas-707: 14.4;PC-3: 8.4;U-266/70: 7.7;U-266/84: 13.6;U-87 MG: 8.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000839, HPA029363" Approved Supported Uncertain "Nucleoplasm,Plasma membrane" NA NA "Cluster 58: Brain - Synaptic function" "Cluster 2: Karpas-707 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" Nucleoplasm "HPA000839: AB_1078929, HPA029363: " "unprognostic (9.63e-3)" "unprognostic (2.04e-1)" "unprognostic (2.02e-1)" "unprognostic (1.18e-2)" "unprognostic (7.07e-2)" "unprognostic (5.42e-2)" "unprognostic (2.34e-6)" "unprognostic (1.24e-1)" "unprognostic (2.70e-1)" "unprognostic (2.39e-2)" "unprognostic (2.63e-2)" "unprognostic (1.73e-1)" "unprognostic (7.29e-6)" "unprognostic (7.42e-3)" "unprognostic (6.20e-2)" "unprognostic (8.13e-2)" 0.0 0.0 10.0 0.0 13.7 0.0 0.0 0.0 13.2 0.9 16.3 0.1 0.1 0.3 0.0 0.4 0.0 0.0 0.0 9.6 15.5 0.0 0.0 0.0 0.0 0.9 4.0 0.0 0.0 0.0 0.6 2.9 3.0 0.1 0.0 9.0 0.1 0.6 0.0 0.2 0.1 0.0 0.6 0.0 0.0 0.7 11.2 0.0 0.0 0.0 0.1 0.4 0.2 2.7 0.0 0.8 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.0 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 14.4 0.0 0.0 0.0 0.0 2.6 6.4 8.4 0.0 0.0 0.0 0.0 0.0 0.2 5.2 0.0 5.3 0.4 0.3 0.1 1.3 0.1 5.3 7.0 0.3 1.6 7.7 13.6 0.0 8.4 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 13.7 0.0 13.2 9.6 15.5 0.9 4.0 3.0 0.6 11.2 2.7 0.0 0.0 0.0 3.6 0.0 0.0 0.1 0.0 0.6 1.2 0.0 0.0 0.3 0.0 0.0 0.0 2.1 3.2 0.0 0.0 0.0 0.0 0.2 0.0 1.1 0.1 0.0 0.0 70.3 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 16.2 1.7 22.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.7 0.0 3.0 0.0 58.3 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.5 1.2 0.9 0.0 1.9 0.0 0.0 0.0 0.5 GABRA4 ENSG00000109158 "Gamma-aminobutyric acid type A receptor subunit alpha4" P48169 4 46918900-46993581 "FDA approved drug targets, Predicted membrane proteins" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 7.5;heart muscle: 2.5" "Group enriched" "Detected in some" 6 "Excitatory neurons: 124.9;Inhibitory neurons: 160.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 149 "REH: 14.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 14: REH - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (2.78e-2)" "unprognostic (6.57e-3)" "unprognostic (2.46e-1)" "unprognostic (2.23e-1)" "unprognostic (3.17e-1)" "unprognostic (1.11e-1)" "unprognostic (6.91e-2)" 0.0 0.0 1.8 0.0 7.5 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 2.5 4.0 2.6 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 7.5 0.0 6.8 4.0 2.6 0.7 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 21.5 0.0 0.5 0.0 0.0 0.6 0.3 0.0 0.6 15.8 0.0 0.0 0.0 0.0 0.2 0.0 0.2 1.9 0.0 1.3 0.0 0.0 0.1 0.0 0.0 124.9 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 160.1 0.4 0.0 0.0 0.0 0.3 0.0 0.1 0.0 8.4 0.0 6.1 0.0 3.5 3.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 1.4 3.8 0.1 0.4 0.1 0.0 0.0 0.0 0.9 0.0 GABRA6 ENSG00000145863 "Gamma-aminobutyric acid type A receptor subunit alpha6" Q16445 5 161547063-161702593 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 114 "brain: 71.1" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in many" 14 "cerebellum: 71.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in some" 40 "cerebellum: 1073.8" "Region enriched" "Detected in some" 37 "cerebellum: 262.3" CAB022462 Approved NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB022462: " "unprognostic (3.79e-2)" 0.0 0.1 0.1 0.0 0.3 0.0 0.0 71.1 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.2 1.8 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 71.1 2.8 0.1 0.3 0.2 1.8 4.9 0.4 0.3 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GABRG3 ENSG00000182256 "Gamma-aminobutyric acid type A receptor subunit gamma3" Q99928 15 26971181-27541984 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Chloride channel, Ion channel" "FDA approved drug targets" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 17.6;retina: 27.1;testis: 9.3" "Group enriched" "Detected in some" 4 "Excitatory neurons: 444.7;Inhibitory neurons: 615.5;Late spermatids: 351.0;Muller glia cells: 179.9" "Cancer enhanced" "Detected in single" "prostate cancer: 1.5" "Region enhanced" "Detected in many" "hypothalamus: 17.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "K-562: 4.5;PC-3: 5.5;SK-MEL-30: 3.5;U-2 OS: 2.5;U-266/70: 3.2;U-87 MG: 14.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA054010 Approved NA NA "Cluster 77: Retina - Visual perception" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA054010: AB_2682342" "unprognostic (1.23e-1)" "unprognostic (1.67e-1)" "unprognostic (1.02e-2)" "unprognostic (3.50e-2)" "unprognostic (2.61e-1)" "unprognostic (2.33e-3)" "unprognostic (1.30e-1)" "unprognostic (2.39e-2)" "unprognostic (5.15e-2)" "unprognostic (2.95e-1)" "unprognostic (4.41e-1)" "unprognostic (1.43e-5)" "unprognostic (1.52e-1)" "unprognostic (1.32e-1)" "unprognostic (2.03e-2)" "unprognostic (1.83e-1)" 0.0 0.4 3.5 0.2 3.0 0.0 0.4 0.0 4.2 0.8 0.0 0.0 0.0 0.1 1.9 0.0 0.4 0.0 0.0 0.9 17.6 0.7 0.1 0.0 0.6 0.5 0.2 0.0 0.0 0.0 3.0 0.0 0.0 6.6 0.0 27.1 0.8 0.2 0.0 0.3 0.0 0.0 0.6 1.0 0.0 9.3 10.2 1.0 1.5 0.0 0.8 0.0 0.2 2.9 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.4 0.3 0.0 5.5 0.0 0.0 1.0 0.0 0.0 0.1 1.0 0.0 0.0 3.5 0.1 0.0 0.0 0.0 0.0 2.5 0.0 0.0 3.2 0.0 0.0 14.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 3.0 0.0 4.2 0.9 17.6 0.5 0.2 0.0 0.6 10.2 2.9 0.1 0.0 0.0 5.5 0.0 0.0 0.1 0.0 0.0 4.6 2.5 1.4 0.9 0.0 0.0 0.0 2.1 0.0 0.1 0.0 0.0 0.0 86.2 3.2 0.1 0.3 0.0 0.0 444.7 0.0 0.0 0.1 0.0 0.4 0.0 0.5 0.0 0.0 0.1 0.0 615.5 0.0 0.0 0.0 0.0 351.0 0.9 0.2 0.0 7.5 0.0 179.9 0.0 16.1 7.9 0.0 0.0 0.7 0.0 3.1 0.0 0.3 0.0 4.6 0.0 0.1 0.1 1.6 7.4 0.0 0.0 0.0 0.1 0.0 0.0 0.2 GAMT "PIG2, TP53I2" ENSG00000130005 "Guanidinoacetate N-methyltransferase" Q14353 19 1397026-1401570 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 615.1;skeletal muscle: 1234.9;tongue: 466.4" "Group enriched" "Detected in many" 4 "Hepatocytes: 718.3;Proximal tubular cells: 417.4" "Cancer enriched" "Detected in all" 5 "liver cancer: 173.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 176.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051806 Approved NA NA 420000 "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA051806: AB_2681619" "unprognostic (3.25e-1)" "unprognostic (7.74e-3)" "unprognostic (3.22e-2)" "unprognostic (6.32e-2)" "unprognostic (4.35e-2)" "unprognostic (1.86e-1)" "unprognostic (2.92e-2)" "unprognostic (2.80e-2)" "unprognostic (1.14e-1)" "unprognostic (2.27e-1)" "unprognostic (3.41e-2)" "unprognostic (7.10e-2)" "unprognostic (6.36e-2)" "prognostic unfavorable (6.57e-4)" "unprognostic (1.78e-1)" "unprognostic (1.82e-1)" "unprognostic (1.54e-2)" 14.0 26.6 69.4 4.5 74.5 8.8 15.6 68.6 79.1 16.5 53.4 10.9 3.2 10.0 141.9 23.0 14.7 9.9 98.1 67.3 67.1 72.0 615.1 8.1 7.7 71.8 68.3 22.8 229.8 37.8 37.4 4.9 70.4 36.5 2.2 15.0 42.6 17.5 1234.9 32.8 6.4 4.6 68.8 10.7 31.8 55.0 76.1 24.8 22.2 466.4 4.3 12.9 15.3 94.5 21.6 24.1 25.2 56.9 30.9 37.3 34.3 25.2 41.2 31.8 28.7 54.8 15.1 11.3 17.2 30.0 3.8 9.1 39.8 15.5 8.5 81.5 46.2 34.9 20.3 176.7 18.2 0.7 11.5 41.8 5.5 33.8 0.1 44.0 6.9 43.0 50.6 26.6 52.6 22.1 103.9 12.0 28.6 10.7 75.4 103.1 22.3 81.4 38.1 19.5 8.4 58.5 1.9 14.3 32.0 16.1 65.3 48.1 12.2 34.6 35.6 1.9 11.6 119.0 24.8 19.5 32.2 46.1 40.7 3.7 2.5 15.3 18.8 3.4 27.3 22.0 26.3 23.8 11.2 32.3 40.6 30.8 1.5 18.2 6.1 47.3 15.8 14.9 69.4 74.5 68.6 79.1 67.3 67.1 71.8 68.3 70.4 68.8 76.1 94.5 9.2 0.0 7.2 5.5 18.0 58.9 42.1 57.8 116.7 41.0 60.3 99.9 99.3 127.2 12.9 16.5 56.3 35.7 15.4 0.8 92.0 39.9 5.2 6.5 7.4 9.2 7.2 35.8 7.4 33.6 41.2 30.9 10.2 4.0 4.5 43.3 18.9 718.3 81.7 18.5 10.1 1.5 6.1 29.5 13.3 16.0 83.9 13.9 32.0 3.7 4.7 57.3 10.3 4.0 36.7 13.5 0.1 139.5 12.5 24.1 0.1 417.4 6.1 61.7 32.9 77.8 47.1 4.3 22.6 42.1 42.9 12.0 19.7 31.1 3.3 23.2 GAN "GAN1, GIG, KLHL16" ENSG00000261609 Gigaxonin Q9H2C0 16 81314944-81390809 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 24.8" "Cell type enhanced" "Detected in many" "Suprabasal keratinocytes: 130.4;Urothelial cells: 188.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 10.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011825, HPA049473" Approved Supported Microtubules NA NA "Cluster 15: NK-cells - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 22: Epithelial cell types - Mixed function" Microtubules "CAB011825: AB_732515, HPA049473: AB_2680782" "unprognostic (1.78e-1)" "unprognostic (1.55e-1)" "unprognostic (8.23e-2)" "unprognostic (2.51e-2)" "unprognostic (8.37e-2)" "unprognostic (1.43e-1)" "unprognostic (2.42e-4)" "unprognostic (1.90e-1)" "unprognostic (3.86e-1)" "unprognostic (1.20e-1)" "unprognostic (1.22e-3)" "unprognostic (5.91e-3)" "unprognostic (3.12e-3)" "unprognostic (5.93e-2)" "unprognostic (9.98e-2)" "unprognostic (1.46e-2)" "unprognostic (5.86e-2)" 1.3 0.9 7.3 0.7 5.7 0.7 2.4 6.6 4.7 2.6 1.0 2.3 0.8 1.3 1.1 5.4 1.3 0.6 1.5 6.9 8.8 1.0 1.1 1.7 0.7 9.3 8.6 1.4 1.2 0.8 1.4 0.8 5.5 2.0 1.2 3.2 2.3 0.7 1.5 24.8 1.4 0.9 8.7 0.9 1.8 0.9 8.7 0.9 1.1 1.4 1.3 1.5 4.3 9.2 1.6 2.0 1.5 2.1 1.9 1.0 10.4 1.2 0.7 0.8 0.3 5.1 1.8 2.5 1.4 1.6 0.4 3.1 2.7 1.3 1.8 0.6 1.4 2.2 1.8 4.1 2.0 2.1 2.4 1.1 3.8 1.3 3.5 1.1 1.7 2.1 2.8 1.1 1.1 9.1 1.9 2.9 4.0 2.2 0.6 3.7 1.4 1.0 1.6 5.0 1.5 1.0 4.3 4.2 1.4 3.6 2.9 2.0 2.5 2.3 2.1 0.8 1.9 2.2 2.7 5.8 1.2 2.4 1.7 0.7 0.4 0.2 0.8 0.4 0.7 0.4 0.8 0.6 0.2 0.5 0.7 0.9 0.3 0.9 0.3 0.9 0.6 0.2 7.3 5.7 6.6 4.7 6.9 8.8 9.3 8.6 5.5 8.7 8.7 9.2 12.2 12.8 8.2 69.5 9.9 91.3 66.8 15.0 34.1 28.4 15.4 18.5 12.5 7.2 29.5 5.5 89.6 19.3 17.4 27.5 0.0 9.4 2.3 11.6 19.3 14.7 5.4 12.6 21.2 6.7 15.4 14.1 17.3 14.0 1.3 7.2 12.1 6.7 5.6 23.5 29.5 15.1 10.2 6.8 30.9 4.6 9.6 8.6 37.4 14.0 7.5 14.0 9.2 22.1 18.3 18.6 16.8 12.8 11.0 75.0 14.8 3.8 30.1 43.8 6.6 20.2 17.6 11.9 16.4 67.1 130.4 21.3 16.1 5.3 15.6 188.7 GATA1 "ERYF1, GATA-1, GF1, NF-E1, NFE1" ENSG00000102145 "GATA binding protein 1" P15976 X 48786562-48794311 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 30 "bone marrow: 59.9" "Cell type enriched" "Detected in some" 4 "Erythroid cells: 165.6" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 6 "eosinophil: 471.7" "Lineage enriched" "Detected in single" 1877 "granulocytes: 471.7" "Group enriched" "Detected in some" 9 "HEL: 221.5;HMC-1: 211.9;K-562: 238.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA000232, HPA000233, CAB009195" Enhanced Supported Nucleoplasm NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 1: K-562 - Erythropoiesis" "Cluster 6: Erythroid cells - Oxygen transport" Nucleoplasm "CAB009195: AB_2232148, HPA000232: AB_1078949, HPA000233: AB_1078951" "unprognostic (1.93e-1)" "unprognostic (7.54e-2)" "unprognostic (8.95e-3)" "unprognostic (3.84e-3)" "unprognostic (2.25e-1)" "unprognostic (3.00e-4)" "unprognostic (4.87e-2)" "unprognostic (3.48e-2)" "unprognostic (4.44e-2)" "unprognostic (1.95e-2)" "unprognostic (6.04e-2)" "unprognostic (7.71e-3)" "unprognostic (4.13e-2)" "unprognostic (2.24e-1)" "unprognostic (2.78e-1)" "unprognostic (9.10e-2)" "unprognostic (2.71e-2)" 0.2 0.1 0.0 0.1 0.2 59.9 0.1 0.2 0.1 0.2 0.0 0.2 0.5 0.3 0.0 0.2 0.1 0.6 0.1 0.0 0.2 0.2 0.3 2.0 0.1 0.3 0.2 0.0 0.0 0.0 0.2 1.0 0.2 0.3 0.3 0.4 0.1 0.1 0.0 0.3 0.5 0.3 0.2 2.0 0.5 1.4 0.2 0.1 0.1 0.4 0.0 0.4 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 221.5 0.0 0.0 0.0 0.2 211.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 238.9 0.4 0.0 0.0 0.1 26.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 83.6 0.2 471.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.9 0.0 0.2 0.0 0.0 4.4 0.0 0.2 0.2 0.1 0.0 0.2 0.3 0.2 0.2 0.2 0.2 0.6 0.0 0.0 1.3 0.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 12.5 0.0 0.0 0.0 0.0 165.6 0.1 0.0 0.5 0.3 0.0 0.0 37.9 0.0 1.1 0.0 0.5 0.0 0.0 0.0 0.0 0.6 0.4 31.5 0.0 9.2 0.0 0.0 0.1 0.0 1.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.1 1.2 0.2 0.0 0.0 GATA6 ENSG00000141448 "GATA binding protein 6" Q92908 18 22169589-22202528 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Atrial septal defect, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 57.8;ovary: 73.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 97.6;Gastric mucus-secreting cells: 100.9;Granulosa cells: 52.9" "Cancer enhanced" "Detected in many" "stomach cancer: 26.0" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 23 "basophil: 4.0" "Lineage enriched" "Detected in single" 23 "granulocytes: 4.0" "Cell line enhanced" "Detected in many" "BEWO: 54.8;CACO-2: 69.7;hTERT-RPE1: 25.5;OE19: 37.6" "Not detected" "Not detected" "Not detected" "Not detected" "CAB011581, HPA066629" Approved Supported Nucleoplasm Yes No "Cluster 34: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "CAB011581: AB_732529, HPA066629: AB_2685695" "unprognostic (1.90e-1)" "unprognostic (1.14e-1)" "unprognostic (1.11e-1)" "unprognostic (4.48e-2)" "unprognostic (1.51e-1)" "unprognostic (1.72e-2)" "unprognostic (2.16e-1)" "unprognostic (9.43e-2)" "unprognostic (4.36e-2)" "unprognostic (3.47e-1)" "unprognostic (2.61e-1)" "unprognostic (8.45e-3)" "prognostic unfavorable (1.92e-9)" "unprognostic (8.75e-3)" "unprognostic (2.07e-1)" "unprognostic (1.91e-1)" "unprognostic (2.12e-2)" 22.2 57.8 0.0 2.5 0.2 0.0 3.8 0.0 0.3 4.9 2.8 11.4 22.8 19.8 1.2 0.8 28.9 11.1 43.9 0.1 0.0 3.0 12.6 14.8 1.9 0.1 0.0 73.0 22.7 0.3 0.6 6.5 0.0 5.5 11.0 0.1 0.8 0.7 0.8 1.5 20.7 9.5 0.2 15.0 49.6 6.3 0.1 0.4 5.3 0.6 0.2 23.0 3.2 0.0 10.1 1.4 0.0 0.0 2.1 1.0 54.8 0.3 0.4 0.8 1.0 69.7 3.8 0.0 3.2 1.2 3.4 10.8 0.4 4.5 1.4 0.0 13.6 0.0 4.3 6.1 14.3 0.6 0.6 0.4 8.9 12.1 9.1 25.5 9.5 0.0 0.5 0.0 0.0 1.5 0.0 0.2 0.1 37.6 9.8 0.0 1.1 0.2 0.4 2.8 0.9 0.1 10.7 6.1 3.0 2.7 1.7 0.0 0.7 1.4 1.6 11.4 1.7 0.0 0.0 0.0 6.2 0.3 9.9 4.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.0 7.3 44.8 30.2 0.0 0.0 0.9 4.0 4.6 1.8 0.0 3.4 2.7 97.6 30.0 6.1 0.0 0.0 0.9 0.9 50.0 0.0 28.4 44.7 6.3 6.3 11.5 26.0 2.7 0.1 19.6 11.2 24.4 100.9 16.6 5.1 52.9 28.5 11.1 1.6 0.0 0.1 45.8 2.0 0.6 0.9 8.8 3.4 0.5 0.0 1.0 0.0 0.0 0.0 0.0 0.2 36.8 27.7 10.1 0.2 4.1 43.3 0.0 3.9 0.0 32.9 0.4 8.6 1.4 1.4 0.9 0.9 1.9 1.3 11.4 47.2 2.9 GDPD1 "FLJ37451, GDE4" ENSG00000153982 "Glycerophosphodiester phosphodiesterase domain containing 1" Q8N9F7 17 59220467-59275970 "Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 34.3;Early spermatids: 47.2;Excitatory neurons: 65.1;Inhibitory neurons: 63.9;Oligodendrocyte precursor cells: 34.2;Oligodendrocytes: 36.5;Spermatocytes: 52.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HEL: 22.3;K-562: 12.5;SCLC-21H: 12.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 36: HEL - Hemostasis" "Cluster 10: Non-specific - Unknown function" "unprognostic (8.33e-2)" "unprognostic (6.63e-3)" "unprognostic (2.68e-2)" "unprognostic (5.98e-3)" "unprognostic (7.12e-2)" "unprognostic (5.35e-2)" "unprognostic (4.85e-6)" "prognostic favorable (2.98e-4)" "unprognostic (2.00e-1)" "unprognostic (1.36e-2)" "unprognostic (1.24e-3)" "unprognostic (2.73e-1)" "unprognostic (1.15e-1)" "unprognostic (2.25e-3)" "unprognostic (4.72e-2)" "unprognostic (1.32e-2)" "unprognostic (6.28e-3)" 0.8 1.8 4.7 0.9 4.3 1.5 1.8 7.0 8.4 1.1 1.9 1.8 5.7 1.5 0.7 0.8 1.4 1.8 1.1 5.1 4.7 2.0 1.0 2.3 0.9 5.9 5.4 0.9 1.1 5.9 1.8 1.3 6.3 2.0 1.5 5.8 2.3 1.5 1.7 1.4 4.2 1.3 2.8 1.5 5.2 8.6 5.1 1.6 2.6 0.7 1.1 1.3 0.8 5.4 0.8 1.0 4.2 3.2 0.6 0.2 2.6 0.5 1.6 0.4 3.3 0.0 1.3 2.0 4.7 0.1 3.0 0.6 6.6 1.1 1.9 2.6 6.8 22.3 0.7 3.2 2.0 1.0 3.2 0.6 5.4 2.1 0.6 1.9 1.9 4.9 12.5 1.3 0.8 1.0 3.9 0.4 0.8 6.6 1.1 2.4 0.4 2.1 2.0 1.2 12.5 3.4 1.0 0.4 4.6 1.3 3.0 1.4 1.6 0.2 1.3 0.2 0.4 3.7 2.3 0.7 1.0 1.2 1.4 2.4 0.5 0.3 0.5 0.7 0.4 0.3 0.4 0.6 0.2 0.5 0.5 0.7 0.9 0.8 0.7 0.7 0.3 0.3 4.7 4.3 7.0 8.4 5.1 4.7 5.9 5.4 6.3 2.8 5.1 5.4 1.6 3.2 8.2 34.3 1.3 0.5 1.5 1.2 1.8 6.1 1.6 1.0 3.1 0.0 8.7 5.5 10.4 0.4 3.2 0.9 0.0 2.2 47.2 1.8 0.4 1.4 1.2 11.3 65.1 1.8 5.5 1.1 9.2 0.7 0.0 4.0 0.7 0.6 1.9 6.7 63.9 3.1 6.1 2.6 1.0 8.3 0.6 3.0 1.8 2.8 2.7 2.3 3.1 34.2 36.5 1.6 2.0 1.5 0.9 1.2 7.6 0.5 5.6 4.4 0.0 1.6 5.7 52.4 17.7 0.5 0.4 2.3 2.5 2.2 1.2 1.6 GDPD5 "GDE2, PP1665" ENSG00000158555 "Glycerophosphodiester phosphodiesterase domain containing 5" Q8WTR4 11 75434640-75525941 "Enzymes, Predicted membrane proteins" Neurogenesis Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 116.6;retina: 83.5" "Group enriched" "Detected in many" 4 "Bipolar cells: 60.9;Cone photoreceptor cells: 148.0;Early spermatids: 52.1;Late spermatids: 178.0;Rod photoreceptor cells: 88.4;Syncytiotrophoblasts: 46.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 7.7" "Group enriched" "Detected in many" 6 "granulocytes: 7.7;T-cells: 2.0" "Cell line enhanced" "Detected in many" "EFO-21: 32.8;fHDF/TERT166: 32.4;HDLM-2: 66.9;U-2 OS: 30.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065257, HPA066762, HPA069281" Uncertain Approved "Golgi apparatus" No No "Cluster 38: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 44: HDLM-2 - Immune response" "Cluster 9: Photoreceptor cells - Phototransduction" "Golgi apparatus" "HPA065257: AB_2685447, HPA066762: AB_2685715, HPA069281: AB_2686107" "unprognostic (1.66e-1)" "unprognostic (1.09e-1)" "unprognostic (2.37e-1)" "prognostic unfavorable (1.29e-4)" "unprognostic (1.48e-1)" "unprognostic (6.12e-2)" "unprognostic (9.97e-3)" "unprognostic (4.05e-1)" "unprognostic (1.44e-1)" "unprognostic (3.49e-1)" "unprognostic (3.07e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (6.59e-9)" "unprognostic (8.64e-2)" "unprognostic (1.30e-1)" "unprognostic (4.39e-2)" "unprognostic (1.65e-1)" 31.0 8.7 19.5 4.8 22.1 12.8 24.6 17.4 12.9 12.4 6.0 7.3 2.7 17.9 1.8 3.3 10.3 4.3 9.5 10.5 14.5 7.8 8.1 15.2 6.7 14.2 27.0 7.3 38.1 0.8 19.1 14.0 10.2 11.5 1.6 83.5 21.3 5.3 13.1 7.4 10.0 6.5 7.4 116.6 4.8 38.9 42.1 3.1 7.7 8.7 4.7 12.6 9.9 12.4 2.1 7.5 3.2 3.7 2.2 1.1 11.1 2.3 3.1 1.1 0.7 10.0 4.4 14.2 32.8 32.4 8.1 4.7 4.0 3.8 0.6 66.9 3.1 2.6 11.7 21.2 3.2 1.6 10.7 2.4 2.0 0.8 1.6 3.2 26.7 12.7 4.7 6.3 1.5 4.5 3.9 7.1 5.7 3.7 10.6 4.5 0.9 3.9 0.9 3.6 1.7 1.2 4.8 18.3 9.3 4.1 2.7 6.3 7.9 7.5 30.4 5.8 2.6 1.6 0.3 2.8 1.7 8.5 0.8 7.7 0.8 0.5 1.2 0.3 1.7 0.6 1.3 0.9 0.2 0.2 0.7 0.9 0.1 0.0 0.0 0.7 2.0 0.5 19.5 22.1 17.4 12.9 10.5 14.5 14.2 27.0 10.2 7.4 42.1 12.4 4.2 6.4 0.0 1.6 5.4 1.0 0.3 0.7 0.6 60.9 3.6 3.4 3.0 1.5 1.3 0.0 148.0 3.2 9.1 0.5 0.0 4.2 52.1 1.0 10.4 7.0 0.0 8.2 5.0 9.3 1.5 6.6 1.1 1.5 4.5 1.6 20.7 2.4 1.9 5.0 15.8 0.7 0.0 2.8 3.7 178.0 5.9 3.1 5.4 8.4 4.9 8.9 1.0 1.0 0.8 4.7 0.3 2.6 5.0 0.8 0.3 0.1 0.8 88.4 0.0 4.6 1.9 12.9 8.2 0.1 1.1 46.0 7.0 0.9 2.0 0.6 GFI1B ZNF163B ENSG00000165702 "Growth factor independent 1B transcriptional repressor" Q5VTD9 9 132944000-132991687 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, DNA-binding, Repressor" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "bone marrow: 39.0" "Cell type enriched" "Detected in some" 4 "Erythroid cells: 99.1" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 20 "basophil: 195.6;eosinophil: 395.8" "Lineage enriched" "Detected in many" 26 "granulocytes: 395.8" "Group enriched" "Detected in some" 5 "HEL: 168.9;HMC-1: 104.6;K-562: 53.0" "Not detected" "Not detected" "Not detected" "Not detected" "CAB004420, HPA006291" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" "Nucleoplasm, Plasma membrane" "CAB004420: AB_2110132, HPA006291: " "unprognostic (1.79e-2)" "unprognostic (2.90e-4)" "unprognostic (6.54e-2)" "unprognostic (1.76e-1)" "unprognostic (2.33e-1)" "unprognostic (1.54e-2)" "unprognostic (2.53e-3)" "unprognostic (1.05e-1)" "unprognostic (2.47e-1)" "unprognostic (1.54e-1)" "unprognostic (4.61e-2)" "unprognostic (3.71e-2)" "unprognostic (2.17e-1)" "unprognostic (2.53e-1)" "unprognostic (1.53e-2)" "unprognostic (1.41e-1)" 0.0 0.0 0.0 0.3 0.1 39.0 0.0 0.2 0.2 0.0 0.2 0.5 0.9 0.0 0.1 0.1 0.0 0.3 0.2 0.1 0.0 0.0 0.2 1.1 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.3 0.0 0.1 0.1 0.4 0.5 1.0 0.1 0.1 1.8 0.3 2.1 0.1 0.1 0.0 0.0 0.2 0.1 0.0 0.4 0.3 0.1 0.0 0.0 0.1 0.5 0.1 0.0 0.0 0.0 0.0 1.9 0.3 23.8 0.0 0.0 0.0 1.5 0.0 0.6 0.0 0.0 0.0 168.9 0.2 0.1 0.0 0.1 104.6 0.0 1.4 0.0 0.2 0.0 0.0 0.0 53.0 0.2 0.0 0.0 0.1 17.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.5 0.0 1.5 0.0 0.0 0.0 195.6 0.3 395.8 0.1 1.9 0.1 0.1 0.1 0.0 1.9 0.2 0.5 0.1 3.9 0.5 15.1 1.0 0.0 12.5 0.0 0.1 0.2 0.2 0.1 0.0 0.4 0.1 0.1 0.1 0.1 0.4 0.2 0.0 0.6 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.2 0.0 1.3 0.0 1.8 0.0 0.0 0.1 0.1 0.8 0.0 0.1 3.8 0.0 0.3 0.4 1.2 99.1 0.4 0.0 0.2 0.3 0.0 0.1 14.5 0.4 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.3 0.0 12.9 0.0 15.8 0.0 0.0 0.6 0.0 0.0 0.5 0.2 0.0 24.2 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.1 0.2 0.4 0.4 0.0 0.0 0.3 0.2 1.0 0.6 0.1 GFRA1 "GDNFR, GDNFRA, GFR-ALPHA-1, RET1L, RETL1, TRNR1" ENSG00000151892 "GDNF family receptor alpha 1" P56159 10 116056925-116273284 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 40.5;Breast glandular cells: 33.1;Fibroblasts: 51.2;Hepatocytes: 42.2;Oligodendrocyte precursor cells: 91.0;Skeletal myocytes: 100.1" "Cancer enriched" "Detected in many" 11 "breast cancer: 40.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+ SV40 Large T+: 44.7;BJ hTERT+ SV40 Large T+ RasG12V: 77.2;EFO-21: 46.5;fHDF/TERT166: 89.3;HBF TERT88: 63.2;MCF7: 59.5;U-251 MG: 53.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043829 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA 140000 "Cluster 68: Epididymis - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" Nucleoplasm "HPA043829: AB_2678689" "unprognostic (2.07e-2)" "unprognostic (2.46e-1)" "unprognostic (7.60e-2)" "unprognostic (1.06e-3)" "unprognostic (4.10e-2)" "unprognostic (6.95e-3)" "unprognostic (2.35e-3)" "unprognostic (1.48e-3)" "unprognostic (3.16e-1)" "unprognostic (2.06e-3)" "unprognostic (1.31e-2)" "unprognostic (2.46e-2)" "unprognostic (1.94e-1)" "unprognostic (1.20e-3)" "unprognostic (1.69e-1)" "unprognostic (2.27e-2)" "unprognostic (3.64e-2)" 10.9 3.4 7.2 4.2 14.9 0.0 23.2 2.6 9.5 9.9 0.3 18.3 1.7 4.9 20.5 6.9 17.2 5.6 4.8 9.7 18.0 6.0 16.0 2.8 4.0 7.8 28.5 4.5 6.6 2.7 3.2 0.0 7.2 4.5 3.9 3.2 6.0 5.4 4.3 7.2 8.2 4.8 6.2 3.9 8.2 3.1 7.6 4.1 2.8 13.9 6.4 7.0 9.2 6.1 0.1 3.7 12.2 0.0 0.0 0.1 0.0 7.9 0.4 44.7 77.2 0.0 0.0 0.0 46.5 89.3 0.0 0.0 0.1 0.0 63.2 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 2.5 0.0 11.5 0.0 3.9 0.0 9.1 0.0 0.0 5.6 59.5 7.6 0.0 5.0 0.0 0.0 0.0 1.9 0.0 5.0 0.0 1.6 0.1 0.0 0.0 0.1 2.1 0.4 0.0 0.4 0.0 0.4 0.1 53.5 0.0 0.0 0.1 0.0 0.0 19.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 14.9 2.6 9.5 9.7 18.0 7.8 28.5 7.2 6.2 7.6 6.1 6.1 0.0 0.0 40.5 0.5 5.7 0.0 0.0 1.8 4.1 33.1 11.0 1.9 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.2 13.2 0.0 0.2 3.2 6.0 0.0 5.1 13.5 0.0 51.2 3.1 0.0 6.3 0.1 0.4 42.2 0.0 0.0 6.6 0.0 0.0 1.0 9.6 12.8 8.1 1.0 5.4 1.9 0.0 12.6 0.0 91.0 0.2 0.2 0.0 0.0 0.1 0.2 0.0 0.9 0.0 0.5 0.0 100.1 16.7 0.1 10.4 0.7 4.5 0.0 0.7 0.1 0.0 0.2 GGNBP2 "DIF-3, DIF3, FLJ21230, FLJ22561, LZK1, ZFP403, ZNF403" ENSG00000278311 "Gametogenetin binding protein 2" Q9H3C7 17 36544912-36589848 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 467.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018914, HPA073392" Approved Approved "Endoplasmic reticulum" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 66: Spermatocytes - Spermatogenesis" "Endoplasmic reticulum" "HPA018914: AB_2294667, HPA073392: AB_2686599" "unprognostic (2.68e-1)" "unprognostic (5.19e-2)" "unprognostic (2.35e-2)" "unprognostic (1.03e-1)" "unprognostic (3.41e-1)" "unprognostic (6.12e-2)" "unprognostic (1.88e-3)" "unprognostic (2.83e-1)" "unprognostic (7.29e-2)" "unprognostic (3.29e-2)" "unprognostic (3.82e-1)" "unprognostic (1.07e-1)" "unprognostic (4.28e-2)" "unprognostic (3.75e-1)" "unprognostic (1.47e-1)" "unprognostic (1.50e-2)" "unprognostic (1.95e-2)" 41.7 30.5 23.8 29.5 23.9 79.9 35.3 26.4 30.0 32.5 24.6 38.9 33.8 34.0 26.6 33.9 34.7 25.2 31.0 24.1 25.5 31.2 36.6 33.5 49.7 25.1 25.7 40.0 35.3 31.5 26.7 27.1 25.9 27.8 30.7 26.8 33.2 23.9 52.7 40.5 44.0 27.5 23.6 39.4 34.8 60.2 24.6 36.6 29.4 32.2 46.5 37.2 34.7 26.1 48.0 49.4 45.8 38.9 53.5 63.9 33.0 60.0 48.1 44.4 44.2 48.6 34.5 64.5 37.2 47.7 44.4 46.9 37.2 55.6 58.1 38.9 36.1 36.2 55.1 43.7 55.1 63.1 47.1 62.3 68.4 45.2 61.4 56.6 38.9 46.2 51.2 62.0 62.5 29.5 65.6 51.2 13.9 31.0 26.1 44.3 60.9 42.8 58.6 93.2 37.1 32.3 58.1 33.5 97.1 46.2 63.0 64.2 39.9 62.4 43.0 41.5 62.4 42.2 50.0 48.7 40.9 34.6 38.6 42.8 31.6 67.8 37.1 35.9 43.6 56.6 46.9 41.5 42.0 48.5 66.0 62.0 44.9 40.4 39.9 84.1 50.1 20.8 23.8 23.9 26.4 30.0 24.1 25.5 25.1 25.7 25.9 23.6 24.6 26.1 85.0 67.3 84.2 38.5 110.2 96.0 98.9 128.8 111.5 70.2 58.9 46.9 81.1 60.1 118.6 31.3 37.5 82.4 132.3 94.7 52.8 74.0 467.4 87.3 84.2 82.2 57.4 71.1 46.9 68.5 77.4 86.6 56.1 104.3 97.5 52.2 65.0 64.7 73.5 57.2 43.3 79.6 101.7 77.9 66.7 130.6 79.6 84.7 58.7 33.7 103.0 71.8 94.7 29.1 48.6 73.2 74.2 72.2 84.4 83.9 124.9 63.6 107.0 71.5 59.2 99.0 114.9 335.2 98.7 91.9 96.5 95.6 117.8 53.5 97.4 102.4 GGPS1 GGPPS1 ENSG00000152904 "Geranylgeranyl diphosphate synthase 1" O95749 1 235327350-235344532 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Isoprene biosynthesis" Transferase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 212.7;Late spermatids: 290.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029472, HPA050727" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 21: Non-specific - Transcription" "Cluster 43: THP-1 - Innate immune response" "Cluster 25: Spermatids - Spermatogenesis" Cytosol Nucleoplasm "HPA029472: AB_10696206, HPA050727: " "unprognostic (7.45e-2)" "unprognostic (3.18e-2)" "unprognostic (1.25e-1)" "unprognostic (2.23e-2)" "unprognostic (1.43e-1)" "unprognostic (3.10e-3)" "prognostic unfavorable (6.69e-4)" "unprognostic (4.50e-2)" "unprognostic (3.66e-2)" "unprognostic (3.77e-3)" "unprognostic (2.66e-2)" "unprognostic (8.77e-3)" "unprognostic (1.95e-2)" "unprognostic (1.99e-1)" "unprognostic (3.35e-2)" "unprognostic (1.41e-1)" "unprognostic (1.70e-2)" 24.0 23.5 20.4 17.3 21.4 7.8 34.1 23.0 27.6 24.5 18.5 24.8 21.2 23.3 30.4 22.4 21.2 20.0 23.5 21.1 22.5 27.8 21.7 20.1 21.3 21.8 20.6 23.3 16.4 21.1 17.6 19.2 22.3 29.4 23.9 38.8 31.2 19.7 29.8 20.3 20.6 25.7 22.3 20.5 20.4 48.2 20.9 27.6 27.4 28.9 21.9 23.6 17.0 25.7 41.3 22.3 54.5 41.5 41.7 59.9 20.5 36.2 50.7 23.6 33.1 17.5 64.5 28.1 51.3 40.6 38.1 33.5 29.4 37.8 31.2 28.8 54.4 24.0 19.7 29.9 46.9 30.0 19.7 39.3 66.5 32.2 43.0 41.8 42.5 46.2 58.5 24.7 31.5 24.6 37.0 35.7 46.4 109.9 11.5 22.6 17.3 32.6 66.2 22.4 43.3 59.8 27.3 61.5 54.7 20.1 76.7 46.5 35.9 27.9 20.8 47.6 34.7 42.0 55.8 34.3 35.4 33.3 51.4 43.7 31.0 48.5 31.5 37.3 32.1 38.6 39.5 33.8 30.4 32.8 36.2 33.4 27.8 31.9 54.2 25.2 42.5 36.8 20.4 21.4 23.0 27.6 21.1 22.5 21.8 20.6 22.3 22.3 20.9 25.7 18.3 32.1 34.5 16.3 27.2 39.9 60.4 64.6 27.9 32.1 29.1 22.4 24.5 17.2 39.5 20.2 43.8 30.7 24.1 21.4 72.4 37.5 212.7 16.8 15.1 29.4 17.4 12.0 26.5 28.3 43.7 31.0 14.3 12.9 24.6 16.4 28.9 13.0 26.8 48.8 25.7 26.1 69.2 26.9 49.0 290.7 35.8 24.3 67.6 20.6 36.7 55.4 36.0 15.6 23.2 31.8 23.3 35.0 8.5 65.6 29.3 61.3 30.4 51.2 26.3 26.1 32.5 111.6 50.0 18.7 40.6 47.1 33.0 30.9 22.7 55.9 GGT1 "CD224, D22S672, D22S732, GGT" ENSG00000100031 "Gamma-glutamyltransferase 1" P19440 22 24594811-24629005 "Candidate cardiovascular disease genes, CD markers, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glutathione biosynthesis, Lipid metabolism" "Acyltransferase, Hydrolase, Protease, Transferase" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 174.8;liver: 115.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 80.1;Cholangiocytes: 48.6;Distal enterocytes: 54.1;Ductal cells: 82.6;Hepatocytes: 40.8;Proximal enterocytes: 111.7;Proximal tubular cells: 62.9" "Cancer enhanced" "Detected in all" "renal cancer: 37.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 103.6;Karpas-707: 165.8;OE19: 169.5;RPMI-8226: 210.3;RPTEC TERT1: 203.2" "HPA045635, HPA047534, HPA065444" Supported Uncertain Vesicles "Intracellular and membrane" NA NA 3600000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" Vesicles "HPA045635: AB_2679400, HPA047534: AB_2680079, HPA065444: AB_2685491" "unprognostic (8.13e-3)" "unprognostic (4.76e-1)" "unprognostic (8.29e-2)" "unprognostic (1.28e-2)" "unprognostic (3.70e-2)" "unprognostic (1.43e-2)" "unprognostic (5.60e-3)" "unprognostic (1.68e-1)" "unprognostic (2.21e-1)" "prognostic favorable (7.44e-4)" "unprognostic (4.55e-2)" "unprognostic (2.55e-2)" "prognostic favorable (4.83e-4)" "unprognostic (1.44e-2)" "unprognostic (5.37e-2)" "unprognostic (1.74e-1)" "unprognostic (6.10e-2)" 3.3 2.4 5.5 6.4 6.7 12.0 24.7 7.0 7.5 28.7 5.1 20.3 84.7 3.0 72.0 3.3 3.3 47.1 7.2 5.1 5.1 174.8 115.7 42.6 5.4 7.2 6.6 3.2 63.1 0.2 5.5 2.4 7.8 48.8 11.0 1.6 9.9 21.6 1.9 4.1 80.4 2.2 5.9 13.3 31.3 18.4 7.1 6.5 15.9 0.4 6.2 5.7 4.3 9.2 1.0 79.7 1.0 0.3 0.0 0.5 2.2 0.5 1.7 0.8 1.0 11.7 18.3 1.0 16.2 0.1 14.8 11.0 6.2 0.8 0.5 103.6 12.3 0.6 40.8 64.3 5.5 1.5 33.2 2.1 0.9 2.5 1.7 1.4 0.5 19.0 8.4 165.8 1.0 1.7 1.6 52.4 6.4 169.5 0.7 0.7 6.8 210.3 203.2 2.9 0.5 1.2 0.4 33.3 0.8 22.2 32.4 39.6 6.4 10.6 9.3 46.6 0.9 48.2 18.4 0.7 19.0 58.7 0.5 4.8 12.3 0.2 1.0 6.0 2.9 2.2 5.0 2.4 6.5 0.2 0.6 1.4 15.9 4.9 4.0 0.1 6.5 5.6 5.5 6.7 7.0 7.5 5.1 5.1 7.2 6.6 7.8 5.9 7.1 9.2 0.2 80.1 22.8 3.3 2.8 0.8 0.1 0.3 4.6 0.5 5.9 2.3 0.7 48.6 4.9 1.8 0.0 1.4 0.7 54.1 1.9 82.6 1.8 1.2 0.6 0.7 1.2 5.3 4.4 8.1 0.4 3.9 15.3 5.1 5.7 0.1 1.8 40.8 4.9 0.0 4.1 4.4 4.1 2.5 1.7 6.7 0.0 2.9 1.8 1.0 5.8 2.5 0.0 1.5 5.7 20.9 20.1 0.4 12.8 2.0 111.7 62.9 1.6 0.1 0.0 0.1 1.0 0.6 0.8 0.4 0.4 0.8 4.0 0.0 6.5 0.1 GGT5 "GGT-REL, GGTLA1" ENSG00000099998 "Gamma-glutamyltransferase 5" P36269 22 24219654-24245108 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glutathione biosynthesis, Leukotriene biosynthesis" "Acyltransferase, Hydrolase, Protease, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endothelial cells: 42.8;Fibroblasts: 58.3;Leydig cells: 36.4;Sertoli cells: 184.1;Smooth muscle cells: 85.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.3;eosinophil: 4.5" "Lineage enriched" "Detected in single" 8 "granulocytes: 4.5" "Cell line enhanced" "Detected in many" "ASC diff: 164.9;ASC TERT1: 124.4;HHSteC: 234.7;HSkMC: 271.7;TIME: 110.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA008121, CAB032489" Uncertain Approved "Nucleoli fibrillar center" "Intracellular and membrane" NA NA 22000000 "Cluster 52: Eosinophils - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoli fibrillar center" "CAB032489: AB_2111010, HPA008121: AB_1078965" "unprognostic (8.14e-2)" "unprognostic (2.53e-1)" "unprognostic (5.66e-2)" "unprognostic (9.94e-2)" "unprognostic (8.13e-2)" "unprognostic (8.21e-2)" "unprognostic (2.33e-2)" "unprognostic (2.90e-1)" "unprognostic (1.81e-2)" "unprognostic (1.07e-1)" "unprognostic (8.37e-2)" "unprognostic (7.94e-2)" "prognostic unfavorable (6.36e-5)" "prognostic unfavorable (4.06e-4)" "prognostic unfavorable (6.97e-4)" "unprognostic (1.79e-1)" "unprognostic (8.33e-2)" 137.6 60.5 39.0 18.6 39.3 1.4 90.6 37.6 41.7 73.2 32.8 27.8 19.4 54.4 12.9 19.6 70.6 37.2 93.4 35.0 45.1 78.2 55.2 37.7 48.0 52.2 46.3 26.6 25.8 13.2 41.1 11.9 46.9 49.3 12.0 2.1 37.1 20.9 23.1 40.1 40.8 32.2 41.9 36.1 40.0 9.6 45.3 10.4 110.2 16.6 18.3 45.1 64.2 38.2 0.0 1.8 0.6 0.0 164.9 124.4 1.1 2.9 0.2 0.1 0.0 0.1 0.1 0.2 3.4 0.2 0.3 0.3 0.1 0.1 0.0 2.2 0.9 6.7 1.0 24.1 234.7 3.0 6.4 271.7 0.1 3.4 3.2 0.4 45.8 0.7 0.4 1.2 44.1 0.4 0.0 22.4 3.6 1.1 0.0 0.1 4.0 1.0 6.1 0.0 0.4 5.9 0.1 7.3 0.1 22.7 1.0 1.7 110.8 0.1 2.3 0.1 0.0 0.3 1.5 0.2 3.9 5.7 0.2 2.3 0.5 4.5 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.1 0.4 0.0 0.0 0.0 0.2 39.0 39.3 37.6 41.7 35.0 45.1 52.2 46.3 46.9 41.9 45.3 38.2 27.2 3.2 16.0 1.0 0.3 7.0 3.3 3.2 0.0 0.0 7.2 4.2 4.4 0.0 17.9 0.0 0.0 0.2 0.4 0.0 0.0 0.6 0.8 0.3 8.3 42.8 0.0 2.7 0.1 0.2 0.2 58.3 1.1 0.4 1.3 0.0 33.5 0.1 2.1 0.0 0.1 0.0 0.0 1.0 12.5 3.3 36.4 1.8 3.6 22.5 3.3 0.3 0.0 0.5 0.0 0.4 0.0 23.7 0.3 2.2 0.0 0.1 2.2 1.0 184.1 33.9 85.6 0.6 0.4 0.3 4.4 0.3 1.1 2.1 0.0 1.4 GIMAP4 "FLJ11110, HIMAP4, IAN1, IMAP4" ENSG00000133574 "GTPase, IMAP family member 4" Q9NUV9 7 150567369-150573953 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 127.7" "Cell type enhanced" "Detected in many" "Adipocytes: 182.3;Endothelial cells: 195.2;Hepatic stellate cells: 222.0;Kupffer cells: 197.2;Macrophages: 110.0;monocytes: 176.0;NK-cells: 344.0;T-cells: 186.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 26 "HUVEC TERT2: 326.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA019135, HPA019137, HPA027198" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" "Vesicles, Cytosol" "HPA019135: AB_1849670, HPA019137: AB_1849672, HPA027198: AB_10602599" "unprognostic (5.03e-2)" "unprognostic (3.30e-3)" "unprognostic (4.08e-2)" "prognostic favorable (7.63e-4)" "unprognostic (1.72e-1)" "unprognostic (1.73e-2)" "unprognostic (7.00e-2)" "unprognostic (2.40e-2)" "unprognostic (1.87e-2)" "unprognostic (1.05e-1)" "unprognostic (1.45e-1)" "unprognostic (1.21e-1)" "prognostic unfavorable (1.13e-4)" "unprognostic (1.65e-1)" "unprognostic (3.32e-2)" "unprognostic (1.39e-1)" "unprognostic (2.29e-1)" 46.1 18.3 15.0 75.1 15.6 4.2 31.8 16.2 21.2 19.7 16.3 21.2 16.5 23.0 9.6 12.0 18.7 24.6 31.3 14.3 16.0 17.3 29.9 50.8 127.7 19.2 18.0 7.7 6.7 9.6 6.0 48.7 18.0 10.2 22.4 1.5 11.2 13.3 17.5 8.4 25.0 38.3 18.8 115.6 18.0 4.2 16.4 30.5 21.1 48.1 85.1 31.1 11.6 18.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 326.4 3.4 0.1 0.3 0.0 0.0 0.4 0.2 0.4 0.0 0.0 12.7 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.5 370.2 5.2 325.8 390.9 404.2 3.0 408.0 402.8 122.1 1.3 424.3 361.9 339.7 263.4 320.4 5.3 312.1 776.9 15.0 15.6 16.2 21.2 14.3 16.0 19.2 18.0 18.0 18.8 16.4 18.7 182.3 3.2 12.4 0.3 7.3 6.8 0.2 0.0 3.4 0.1 2.2 4.7 9.9 5.7 1.8 11.0 0.0 0.6 82.6 0.0 0.0 0.2 0.6 0.3 0.4 195.2 0.0 9.7 0.5 0.2 0.8 9.0 2.0 0.3 6.3 0.0 222.0 3.7 96.4 0.0 0.1 0.0 0.0 197.2 20.9 1.7 5.0 110.0 10.6 18.7 176.0 0.2 344.0 0.0 0.1 0.1 0.0 0.0 14.7 0.4 0.0 1.9 0.7 0.4 13.1 3.9 7.9 0.0 0.8 1.1 6.1 0.8 186.2 0.8 0.0 0.3 GIMAP6 "FLJ22690, IAN6" ENSG00000133561 "GTPase, IMAP family member 6" Q6P9H5 7 150625375-150632648 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 95.3;Endothelial cells: 83.5;Hepatic stellate cells: 92.1;Kupffer cells: 75.2;monocytes: 37.4;NK-cells: 91.6;T-cells: 41.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 6 "monocytes: 75.1;NK-cells: 217.3;T-cells: 127.2" "Cell line enhanced" "Detected in some" "HMC-1: 18.4;HUVEC TERT2: 124.9;MOLT-4: 43.3;TIME: 35.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026715, HPA050740" Approved NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" "HPA026715: AB_1849675, HPA050740: AB_2797239" "unprognostic (8.58e-2)" "unprognostic (1.34e-2)" "unprognostic (6.56e-3)" "prognostic favorable (3.12e-4)" "unprognostic (1.22e-1)" "prognostic favorable (2.91e-4)" "prognostic favorable (1.56e-4)" "unprognostic (2.88e-2)" "unprognostic (8.75e-2)" "unprognostic (8.87e-2)" "unprognostic (4.68e-2)" "unprognostic (3.52e-1)" "prognostic unfavorable (5.27e-4)" "unprognostic (2.75e-1)" "unprognostic (2.48e-2)" "unprognostic (3.01e-1)" "unprognostic (1.27e-1)" 42.0 9.4 9.7 33.9 9.7 2.5 21.8 9.7 10.6 14.9 8.0 12.0 13.6 19.3 7.3 8.4 16.9 14.7 29.1 8.0 9.5 12.4 12.7 38.8 50.2 11.4 10.5 5.7 5.2 8.0 3.3 32.3 11.3 6.4 12.2 0.6 7.8 10.0 24.7 6.4 18.7 25.8 10.9 64.0 11.6 3.2 11.6 29.3 14.2 34.7 33.9 16.5 6.5 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 3.8 0.0 6.3 0.0 0.0 0.0 0.4 18.4 0.1 0.0 0.0 0.0 0.0 124.9 0.5 0.0 4.6 0.0 0.0 43.3 5.4 0.0 0.0 0.0 4.6 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 10.8 35.9 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.2 13.0 0.0 11.6 58.1 2.1 112.9 75.1 127.2 0.4 104.3 120.2 22.1 0.3 108.3 103.0 8.0 217.3 60.2 0.7 105.7 163.5 9.7 9.7 9.7 10.6 8.0 9.5 11.4 10.5 11.3 10.9 11.6 10.1 95.3 0.0 1.1 0.0 3.1 3.8 0.1 0.0 0.6 0.0 1.1 1.0 7.4 0.0 0.0 0.0 0.0 0.2 24.5 0.1 0.0 0.0 0.4 0.1 0.2 83.5 0.0 19.4 0.0 0.2 0.3 3.4 0.0 0.2 2.5 0.3 92.1 1.7 30.6 0.0 0.0 0.1 0.0 75.2 6.5 2.2 1.2 20.0 1.8 13.1 37.4 0.1 91.6 0.0 0.1 0.1 0.0 0.0 2.9 0.1 0.0 0.2 0.7 0.4 0.0 2.6 2.2 0.3 0.1 0.4 3.1 0.4 41.2 1.2 0.0 0.3 GIMAP7 "IAN7, MGC27027" ENSG00000179144 "GTPase, IMAP family member 7" Q8NHV1 7 150514872-150521073 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 170.1" "Cell type enhanced" "Detected in many" "Adipocytes: 265.8;Endothelial cells: 263.3;Hepatic stellate cells: 267.4;Kupffer cells: 156.8;monocytes: 140.8;NK-cells: 632.4;T-cells: 255.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "monocytes: 666.6;NK-cells: 1121.0;T-cells: 2269.3" "Group enriched" "Detected in some" 9 "HUVEC TERT2: 92.9;MOLT-4: 78.6" "Not detected" "Not detected" "HPA020266, HPA020268" Enhanced Supported "Golgi apparatus,Vesicles" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Golgi apparatus, Vesicles" "HPA020266: AB_1849680, HPA020268: AB_1849682" "unprognostic (4.85e-3)" "unprognostic (1.65e-3)" "unprognostic (6.11e-2)" "unprognostic (1.32e-2)" "unprognostic (3.71e-1)" "prognostic favorable (7.43e-4)" "prognostic favorable (8.98e-5)" "unprognostic (6.49e-3)" "unprognostic (5.24e-2)" "unprognostic (6.12e-3)" "unprognostic (2.36e-2)" "unprognostic (2.81e-1)" "unprognostic (2.07e-3)" "unprognostic (2.07e-1)" "unprognostic (3.14e-2)" "unprognostic (2.01e-1)" "unprognostic (8.86e-2)" 49.8 15.0 16.3 73.6 17.4 6.6 37.4 17.1 21.3 19.2 16.0 20.3 21.1 27.8 19.8 12.6 21.5 22.1 40.1 15.5 17.2 20.9 20.4 61.0 170.1 19.0 17.8 7.4 7.6 10.5 5.6 31.5 19.1 10.9 23.3 1.2 13.7 12.0 27.8 9.3 40.1 33.6 17.6 124.3 22.0 4.5 18.0 52.5 28.2 56.1 99.2 29.6 13.0 17.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 92.9 9.4 0.0 0.0 0.0 0.0 78.6 0.1 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 35.7 656.5 9.6 1184.0 595.9 1164.2 6.5 1762.9 1440.6 286.3 6.5 2269.3 1597.2 52.5 1121.0 666.6 16.3 1076.9 2581.7 16.3 17.4 17.1 21.3 15.5 17.2 19.0 17.8 19.1 17.6 18.0 17.6 265.8 0.0 13.2 0.3 13.1 2.4 0.4 0.0 2.8 0.0 2.8 5.6 14.6 5.7 0.6 1.8 0.0 0.2 125.1 0.2 0.0 0.5 1.3 0.9 0.6 263.3 0.0 17.0 0.0 0.7 0.0 8.0 3.1 0.7 13.9 0.0 267.4 5.3 15.5 0.0 0.0 0.1 0.0 156.8 10.6 2.0 2.5 54.9 1.8 22.5 140.8 0.4 632.4 0.5 0.1 0.4 1.2 0.4 19.3 0.2 0.0 1.7 0.7 0.4 0.0 6.0 9.4 0.2 0.9 1.1 3.3 0.4 255.9 0.9 0.2 0.0 GJA10 CX62 ENSG00000135355 "Gap junction protein alpha 10" Q969M2 6 89894469-89921760 "Predicted membrane proteins" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 92 "Horizontal cells: 18.5" "Cancer enriched" "Detected in single" 7 "testis cancer: 1.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA021145 Uncertain NA NA "Cluster 62: Horizontal cells - Visual perception" "HPA021145: AB_2670600" "unprognostic (1.09e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GJA3 "CX46, CZP3" ENSG00000121743 "Gap junction protein alpha 3" Q9Y6H8 13 20138255-20161052 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 7.8;parathyroid gland: 4.0;placenta: 2.5" "Cell type enriched" "Detected in some" 5 "Cardiomyocytes: 13.6" "Group enriched" "Detected in some" 4 "head and neck cancer: 1.3;melanoma: 3.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 4.4;CAPAN-2: 7.7;HL-60: 6.6;U-266/84: 4.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA014821 Supported NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA014821: AB_2669097" "unprognostic (2.32e-1)" "unprognostic (1.01e-1)" "unprognostic (4.37e-2)" "unprognostic (2.58e-3)" "unprognostic (2.98e-2)" "unprognostic (1.04e-2)" "unprognostic (6.87e-3)" "unprognostic (1.84e-1)" "unprognostic (1.73e-1)" "unprognostic (7.52e-2)" "unprognostic (7.70e-2)" "unprognostic (4.02e-2)" "unprognostic (9.65e-8)" "unprognostic (2.87e-1)" "unprognostic (1.91e-1)" "unprognostic (2.55e-2)" "unprognostic (8.04e-3)" 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.1 7.8 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 4.0 0.0 2.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 1.2 0.1 0.0 0.1 0.0 1.0 0.0 0.2 0.0 4.4 0.2 0.0 3.7 0.1 1.1 0.0 0.5 3.5 0.6 0.7 0.4 7.7 0.0 0.1 1.3 1.2 0.1 2.5 2.1 0.5 0.2 1.9 1.8 0.0 0.0 0.0 6.6 0.0 0.2 1.2 0.1 0.3 0.0 0.0 2.8 0.5 0.0 0.1 0.0 0.0 0.0 0.5 0.1 1.5 0.3 0.0 0.0 0.0 0.5 0.0 0.0 0.3 0.0 3.7 0.1 0.8 1.4 0.0 0.0 0.0 1.5 0.2 1.7 4.7 0.0 0.0 0.1 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 1.2 0.0 0.0 0.0 13.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.2 2.7 0.3 0.0 0.0 0.1 0.0 0.0 0.1 GJA4 CX37 ENSG00000187513 "Gap junction protein alpha 4" P35212 1 34792999-34795747 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Hepatic stellate cells: 234.2;Sertoli cells: 664.0;Smooth muscle cells: 306.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "EFO-21: 74.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA047981 Approved NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" "HPA047981: AB_2680228" "unprognostic (2.22e-2)" "unprognostic (2.05e-1)" "unprognostic (1.12e-2)" "unprognostic (2.67e-2)" "unprognostic (4.48e-1)" "unprognostic (5.24e-3)" "prognostic favorable (3.28e-4)" "unprognostic (2.01e-2)" "unprognostic (2.23e-1)" "unprognostic (8.17e-2)" "unprognostic (6.83e-2)" "unprognostic (8.81e-2)" "prognostic unfavorable (7.44e-4)" "unprognostic (3.47e-2)" "unprognostic (3.74e-2)" "unprognostic (3.82e-3)" "unprognostic (7.96e-3)" 79.4 20.4 10.1 9.3 11.0 0.3 61.5 9.8 15.1 26.6 9.0 14.7 2.8 33.8 5.5 7.5 40.0 17.3 83.6 10.5 9.6 35.8 17.3 40.7 11.3 10.3 10.2 18.0 7.0 10.6 6.4 61.6 10.6 18.8 3.8 0.8 10.1 10.7 34.7 14.8 13.9 15.2 10.2 9.9 12.9 5.4 10.2 2.7 39.8 35.2 5.4 28.1 22.4 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 74.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 9.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 8.5 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 10.1 11.0 9.8 15.1 10.5 9.6 10.3 10.2 10.6 10.2 10.2 9.9 90.4 0.0 0.0 0.3 0.6 9.7 1.9 0.2 1.2 0.2 1.1 1.5 9.0 1.5 0.6 3.7 0.0 0.2 0.7 0.0 0.0 11.0 0.1 3.1 0.5 81.4 15.6 2.7 0.0 0.0 0.1 7.7 2.6 4.9 0.0 0.5 234.2 1.8 0.3 0.0 0.0 0.0 0.0 6.3 10.7 1.1 0.9 2.2 19.6 1.0 0.6 0.1 0.0 0.0 0.0 1.0 0.0 12.8 0.2 3.0 0.0 0.1 1.2 0.7 664.0 4.4 306.3 0.2 1.2 0.7 8.7 0.0 1.3 1.6 0.1 5.2 GKAP1 "FKSG21, GKAP42" ENSG00000165113 "G kinase anchoring protein 1" Q5VSY0 9 83739425-83829516 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "skeletal muscle: 50.1;testis: 199.5" "Group enriched" "Detected in all" 6 "Early spermatids: 1339.6;Late spermatids: 481.5;Spermatocytes: 642.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-266/84: 34.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035117, HPA035118, HPA066173" Enhanced Supported Approved "Centriolar satellite,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 78: Testis - Spermatogenesis" "Cluster 16: U-266 - Nucleosome" "Cluster 66: Spermatocytes - Spermatogenesis" "Centriolar satellite, Cytosol" "HPA035117: AB_2674473, HPA035118: AB_10671100, HPA066173: AB_2732740" "unprognostic (1.91e-1)" "unprognostic (2.94e-2)" "unprognostic (1.12e-1)" "unprognostic (1.16e-1)" "unprognostic (9.62e-2)" "unprognostic (2.50e-1)" "unprognostic (2.52e-3)" "unprognostic (7.66e-3)" "unprognostic (3.04e-1)" "unprognostic (1.86e-2)" "prognostic favorable (6.96e-5)" "unprognostic (4.18e-1)" "prognostic favorable (1.05e-6)" "unprognostic (9.73e-2)" "unprognostic (1.38e-2)" "unprognostic (2.06e-1)" "unprognostic (6.24e-3)" 7.9 6.4 18.5 2.7 20.3 3.9 6.2 26.9 23.5 8.2 25.7 12.1 4.3 8.8 6.7 3.7 8.2 5.0 14.9 17.0 19.9 7.4 9.4 4.2 3.9 19.2 19.3 12.9 8.4 10.3 12.5 2.4 19.6 8.8 3.5 22.5 5.2 9.0 50.1 2.0 5.3 6.1 19.4 4.1 7.6 199.5 20.7 9.1 9.9 26.4 3.8 7.8 4.6 23.2 7.2 8.4 6.0 8.0 0.8 0.0 9.0 2.6 2.1 4.1 4.2 1.1 3.7 10.8 2.7 1.2 13.7 1.4 6.0 0.7 7.0 13.2 5.6 6.4 4.1 6.2 8.7 2.9 0.6 0.2 4.8 2.1 2.2 11.9 3.8 10.2 5.3 8.6 1.2 6.6 16.1 9.8 5.1 3.3 4.9 10.9 13.7 3.7 4.3 1.1 20.3 11.9 6.0 2.7 4.8 9.2 1.2 5.8 1.3 1.4 10.0 0.9 4.7 14.6 34.5 4.3 3.0 2.0 1.6 1.2 0.2 0.2 0.5 0.0 0.5 0.7 0.5 0.5 0.2 0.6 0.3 0.7 1.1 2.0 0.1 0.1 0.6 0.0 18.5 20.3 26.9 23.5 17.0 19.9 19.2 19.3 19.6 19.4 20.7 23.2 14.2 6.4 11.2 32.0 17.9 7.0 14.7 2.7 2.8 54.1 21.1 17.3 51.7 20.0 2.6 14.7 45.9 8.8 13.1 5.4 13.7 13.4 1339.6 18.4 5.4 12.6 13.1 14.3 19.7 6.6 2.9 8.6 5.1 13.6 2.5 28.9 10.0 21.3 4.1 121.1 32.6 10.8 4.1 4.4 6.2 481.5 26.4 7.7 10.6 27.2 2.3 51.1 8.2 36.2 42.0 4.9 7.4 21.4 15.0 17.5 9.0 14.3 5.4 85.2 26.3 32.0 11.0 642.9 79.4 4.2 4.5 2.9 13.7 15.4 12.2 8.9 GLB1L MGC10771 ENSG00000163521 "Galactosidase beta 1 like" Q6UWU2 2 219236598-219245478 "Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 52.3" "Cell type enhanced" "Detected in many" "Early spermatids: 41.5;Spermatocytes: 117.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 19.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA043058 Enhanced "Secreted - unknown location" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA043058: AB_10806375" "unprognostic (4.30e-2)" "unprognostic (6.93e-2)" "unprognostic (2.68e-2)" "unprognostic (2.08e-3)" "unprognostic (4.35e-2)" "unprognostic (1.51e-1)" "unprognostic (1.67e-3)" "unprognostic (3.32e-2)" "unprognostic (4.77e-1)" "unprognostic (2.39e-1)" "unprognostic (8.48e-3)" "unprognostic (3.27e-1)" "unprognostic (3.62e-1)" "unprognostic (1.28e-1)" "unprognostic (9.23e-3)" "unprognostic (1.33e-1)" "unprognostic (8.50e-2)" 4.6 4.8 3.1 4.0 3.4 4.5 5.3 3.3 3.0 5.3 14.7 3.1 3.1 5.9 11.4 2.5 23.1 9.0 2.2 3.0 3.7 13.6 3.1 5.3 3.0 5.5 7.0 7.1 3.1 14.4 6.8 8.5 4.5 5.6 3.7 8.0 4.5 4.8 0.9 4.6 4.1 5.8 4.4 4.9 2.8 52.3 3.7 3.4 8.4 1.0 3.4 5.9 2.1 5.6 2.8 4.8 7.4 5.9 8.0 9.8 3.7 4.6 9.7 5.7 5.3 1.9 7.7 0.9 4.1 4.1 4.3 1.5 1.9 4.6 4.5 2.6 3.6 2.9 6.9 4.5 19.7 1.1 4.4 11.4 2.9 5.4 3.3 13.5 5.3 4.3 1.8 5.3 5.4 4.0 2.5 2.7 1.3 1.0 1.3 2.5 4.1 4.0 11.5 1.6 4.7 4.2 3.9 5.3 4.3 4.9 8.4 2.6 4.1 4.7 5.8 2.8 2.6 5.0 1.7 1.5 8.8 1.2 12.3 1.9 5.1 0.3 0.7 6.4 0.4 0.4 0.5 0.7 2.1 1.0 1.1 0.7 2.1 1.0 5.4 0.9 0.2 1.7 3.1 3.4 3.3 3.0 3.0 3.7 5.5 7.0 4.5 4.4 3.7 5.6 3.2 3.2 5.1 3.3 1.3 1.8 2.6 3.6 0.6 4.7 4.9 5.6 1.9 1.5 6.3 3.7 12.5 3.4 1.9 1.1 3.9 3.8 41.5 15.7 3.9 4.2 4.9 1.3 0.9 1.8 2.2 8.4 1.1 2.2 0.0 2.7 8.6 1.3 14.5 3.3 1.1 3.2 2.0 5.6 2.4 25.6 10.8 4.4 8.8 1.9 2.7 5.0 3.1 1.0 0.5 2.1 3.3 6.4 1.8 2.7 6.5 16.5 23.9 10.2 6.6 3.8 2.2 117.4 9.7 1.8 1.7 1.4 2.0 7.0 2.4 1.7 GMCL1 "BTBD13, FLJ13057, GCL1, SPATA29" ENSG00000087338 "Germ cell-less 1, spermatogenesis associated" Q96IK5 2 69829660-69881384 "Plasma proteins, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 264.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 93.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039579 Approved NA NA "Cluster 10: Basophils - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 29: Early spermatids - Spermatogenesis" "HPA039579: AB_10805480" "unprognostic (1.89e-2)" "unprognostic (4.95e-2)" "unprognostic (2.53e-2)" "unprognostic (1.79e-2)" "unprognostic (4.09e-2)" "unprognostic (1.96e-1)" "unprognostic (5.20e-2)" "unprognostic (2.60e-3)" "unprognostic (1.27e-1)" "unprognostic (8.80e-2)" "unprognostic (3.04e-1)" "unprognostic (5.94e-2)" "unprognostic (2.48e-3)" "unprognostic (1.10e-2)" "unprognostic (1.68e-1)" "unprognostic (2.69e-2)" "unprognostic (1.01e-1)" 9.4 6.5 4.4 8.1 4.8 13.6 10.6 5.3 6.7 8.6 11.6 10.7 15.9 7.7 8.8 8.2 7.9 8.5 4.8 5.2 4.4 11.5 10.7 7.7 12.0 4.4 4.7 8.5 9.1 19.1 6.5 9.3 4.3 11.1 12.2 6.1 9.4 8.7 4.1 8.8 13.1 6.4 4.6 9.1 8.6 16.3 4.5 18.5 9.2 5.4 12.2 8.3 6.3 5.3 14.7 10.3 17.2 18.4 15.0 13.1 18.4 12.1 8.0 8.1 13.7 9.9 13.5 30.7 9.7 8.0 9.5 14.2 20.3 10.5 14.1 14.2 21.2 48.0 11.3 22.8 9.9 36.1 32.4 7.2 11.3 6.4 14.9 10.5 14.5 23.2 19.5 21.8 12.9 12.6 37.1 33.7 18.4 24.9 9.6 26.1 22.6 23.6 11.9 22.2 27.0 22.5 13.2 19.1 14.8 13.4 12.6 22.2 9.0 12.4 15.5 19.4 14.7 22.1 28.6 18.9 12.8 29.5 13.0 93.5 8.0 40.1 11.1 6.3 19.1 8.8 10.9 13.7 7.5 8.3 15.6 15.5 26.8 26.8 10.3 7.9 15.5 9.4 4.4 4.8 5.3 6.7 5.2 4.4 4.4 4.7 4.3 4.6 4.5 5.3 17.9 28.9 27.4 22.9 25.9 26.8 21.4 19.5 27.3 22.5 28.3 20.4 7.6 74.4 22.0 18.4 27.1 38.3 42.5 40.0 41.1 36.1 264.8 26.7 21.8 19.5 23.4 29.0 68.1 17.5 51.9 19.4 16.3 18.4 22.2 24.2 26.4 25.4 15.9 21.9 63.8 37.0 44.7 23.8 13.1 50.8 15.8 15.0 16.0 11.2 22.8 44.2 50.4 42.7 45.6 15.2 21.7 22.6 28.2 33.0 42.1 23.2 38.4 37.0 13.1 26.0 21.1 44.2 45.1 38.4 27.7 81.5 36.7 17.5 30.6 25.7 GNG4 ENSG00000168243 "G protein subunit gamma 4" P50150 1 235547685-235650754 "Predicted intracellular proteins, RAS pathway related proteins" Transducer "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 40.9;ovary: 32.1;pituitary gland: 32.0" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 24.4;Enteroendocrine cells: 43.0;Inhibitory neurons: 43.3;Intestinal goblet cells: 16.2;Oligodendrocyte precursor cells: 25.1;Prostatic glandular cells: 24.1;Proximal enterocytes: 24.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.2" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.2" "Cell line enhanced" "Detected in many" "NTERA-2: 151.4;SCLC-21H: 158.4;SH-SY5Y: 222.8;U-2197: 67.2" "Region enriched" "Detected in all" 6 "olfactory bulb: 469.3" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (1.50e-3)" "unprognostic (8.33e-3)" "unprognostic (7.14e-2)" "unprognostic (1.56e-2)" "unprognostic (2.48e-1)" "unprognostic (4.94e-2)" "unprognostic (2.22e-2)" "unprognostic (3.10e-2)" "unprognostic (3.47e-2)" "unprognostic (3.49e-1)" "unprognostic (1.79e-2)" "unprognostic (1.54e-1)" "unprognostic (2.56e-9)" "unprognostic (1.22e-1)" "unprognostic (1.62e-1)" "unprognostic (1.68e-3)" "unprognostic (5.01e-3)" 1.4 11.3 20.0 1.7 25.6 0.1 0.6 7.9 21.0 4.7 3.1 3.6 2.5 9.5 0.1 14.4 3.3 0.5 0.1 15.4 40.9 1.9 0.3 0.1 5.7 21.3 28.2 32.1 5.1 0.0 32.0 1.7 25.4 22.6 3.0 2.4 2.0 0.7 0.1 0.5 5.3 6.6 18.9 0.1 3.1 1.7 33.6 4.9 0.3 0.0 3.4 1.0 2.4 7.3 37.2 2.0 26.4 0.0 0.0 1.3 2.4 0.1 0.4 3.3 4.5 0.1 1.5 0.0 0.3 11.2 9.0 3.3 28.4 1.2 6.7 19.4 10.2 0.1 0.7 14.4 0.4 0.2 12.1 2.4 0.2 0.4 0.9 0.0 0.0 2.0 0.3 0.1 2.1 0.1 7.6 1.2 151.4 0.1 0.1 0.0 13.8 0.7 0.0 1.1 158.4 222.8 0.9 0.3 3.2 1.7 0.2 5.3 0.0 1.7 5.0 67.2 5.2 3.5 0.2 0.0 4.9 0.1 44.5 1.2 0.1 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.2 0.1 0.0 0.3 0.2 0.1 0.0 0.1 0.1 20.0 25.6 7.9 21.0 15.4 40.9 21.3 28.2 25.4 18.9 33.6 7.3 0.1 0.0 0.0 2.9 0.2 0.5 2.6 0.3 0.0 2.3 0.2 0.9 0.5 0.0 1.0 0.0 0.0 7.7 2.7 1.6 0.0 0.0 1.1 1.5 24.4 1.4 43.0 0.0 2.3 9.0 10.0 1.7 0.0 0.8 0.0 3.8 0.0 0.0 0.9 1.7 43.3 16.2 4.1 0.0 3.6 1.0 0.3 1.1 0.0 4.7 1.0 0.4 0.0 25.1 0.8 1.6 1.3 0.4 0.1 24.1 24.5 4.9 0.2 1.3 0.0 0.2 1.6 1.8 4.4 0.0 0.0 6.3 1.1 0.3 4.6 1.5 GNPAT "DAP-AT, DAPAT, DHAPAT" ENSG00000116906 "Glyceronephosphate O-acyltransferase" O15228 1 231241207-231277973 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Acyltransferase, Transferase" "Cataract, Disease variant, Dwarfism, Rhizomelic chondrodysplasia punctata" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 119.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (8.87e-2)" "unprognostic (3.28e-2)" "unprognostic (3.36e-2)" "unprognostic (2.56e-2)" "unprognostic (5.25e-3)" "unprognostic (1.91e-1)" "unprognostic (5.07e-2)" "unprognostic (6.72e-2)" "unprognostic (1.14e-1)" "unprognostic (1.10e-1)" "unprognostic (1.48e-2)" "unprognostic (2.68e-1)" "prognostic unfavorable (8.29e-6)" "unprognostic (5.69e-2)" "unprognostic (1.66e-1)" "unprognostic (4.48e-2)" "unprognostic (2.68e-1)" 22.4 26.9 21.6 20.5 24.0 17.3 21.7 23.9 28.2 18.3 25.2 30.0 30.0 20.3 23.7 22.1 27.9 18.2 44.9 22.0 23.5 25.7 30.9 18.7 23.6 24.1 22.5 22.5 29.5 22.6 17.9 19.4 23.3 22.8 24.8 17.0 26.4 20.9 101.9 23.6 28.1 26.4 23.6 18.5 26.9 32.0 23.2 27.5 20.8 84.1 25.8 21.5 17.0 26.1 39.8 43.6 60.4 46.1 48.7 71.4 40.7 32.9 37.1 34.1 39.1 56.1 48.3 57.0 40.4 49.5 35.9 41.9 40.6 44.7 50.0 64.8 37.2 41.2 41.4 81.7 49.4 70.9 31.4 50.1 53.8 35.5 39.6 44.5 81.2 56.0 61.1 53.3 71.7 13.1 63.6 41.0 97.1 112.0 49.5 68.7 81.0 66.9 42.7 29.2 40.0 57.1 55.2 30.7 49.1 23.8 53.7 110.7 42.8 34.5 32.1 50.5 83.3 68.2 93.6 65.1 49.8 58.8 65.3 34.1 36.4 37.3 23.7 37.1 27.2 35.1 30.6 31.3 36.4 37.7 26.4 24.4 14.3 26.9 50.3 17.2 37.9 29.8 21.6 24.0 23.9 28.2 22.0 23.5 24.1 22.5 23.3 23.6 23.2 26.1 17.7 25.6 20.8 19.9 32.3 13.5 19.5 23.1 16.5 23.3 14.9 12.6 55.8 30.0 21.2 27.6 39.6 25.3 20.1 16.4 17.6 41.5 70.3 21.5 19.4 21.4 28.2 13.2 18.9 43.4 19.2 19.5 21.4 14.1 11.4 30.1 19.2 26.9 27.4 11.8 18.6 21.0 22.4 24.8 18.3 119.2 25.4 21.8 12.4 15.9 38.7 22.7 26.8 17.1 29.2 40.2 30.3 26.7 30.1 24.9 41.7 28.0 30.8 24.2 19.7 16.5 22.4 50.9 31.5 18.8 13.9 12.4 24.5 19.7 30.1 19.0 GOLGA8F DKFZp434P162 ENSG00000153684 "Golgin A8 family member F" Q08AF8 15 28378621-28392018 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 180 "testis: 20.1" "Cell type enhanced" "Detected in some" "Early spermatids: 1.7;Spermatocytes: 1.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 8 "NB-4: 2.1" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 24: NB-4 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (4.96e-2)" 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GORASP1 "FLJ23443, GOLPH5, GRASP65, P65" ENSG00000114745 "Golgi reassembly stacking protein 1" Q9BQQ3 3 39096599-39107863 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 98.9;Late spermatids: 56.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056283 Supported Supported "Golgi apparatus" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 34: Spermatids - Unknown function" "Golgi apparatus" "HPA056283: AB_2683085" "unprognostic (1.06e-1)" "unprognostic (8.31e-2)" "unprognostic (1.05e-1)" "prognostic favorable (6.92e-6)" "unprognostic (2.77e-1)" "unprognostic (1.98e-2)" "prognostic unfavorable (5.13e-4)" "unprognostic (2.13e-2)" "unprognostic (8.79e-3)" "unprognostic (1.05e-1)" "unprognostic (1.76e-1)" "unprognostic (1.73e-3)" "prognostic favorable (1.91e-6)" "unprognostic (1.21e-1)" "unprognostic (1.41e-1)" "unprognostic (1.44e-1)" "unprognostic (3.24e-3)" 16.9 13.5 35.4 12.8 36.4 11.5 18.6 38.7 35.7 25.2 30.3 23.6 13.6 18.8 16.6 20.0 22.2 15.6 21.3 34.1 35.9 26.9 26.3 19.6 13.4 41.7 36.9 13.3 24.5 22.5 15.4 21.0 38.0 22.1 26.0 20.6 26.2 30.7 16.3 16.4 18.5 24.0 42.0 21.5 19.1 10.5 38.8 11.8 18.4 19.0 17.4 17.9 14.8 46.6 15.6 19.0 18.0 17.8 42.8 28.1 16.6 27.1 31.1 27.5 24.6 11.3 18.4 16.8 15.7 41.4 17.2 24.7 20.7 32.2 19.3 22.4 14.3 23.8 18.7 16.0 19.3 20.0 25.8 22.0 43.8 28.5 28.0 30.6 38.2 6.0 19.8 20.3 26.3 22.6 5.6 18.9 13.1 35.7 23.1 6.0 10.7 23.8 27.4 28.1 7.1 14.0 25.7 51.4 16.1 24.4 33.2 20.7 29.0 15.4 14.3 37.0 15.0 14.1 14.8 4.1 18.3 16.7 23.0 6.5 12.0 7.0 3.3 12.7 4.5 11.7 4.1 3.1 12.8 9.3 4.7 3.4 6.9 2.8 17.2 7.2 6.7 8.0 35.4 36.4 38.7 35.7 34.1 35.9 41.7 36.9 38.0 42.0 38.8 46.6 21.1 3.2 9.8 23.2 8.7 4.1 10.6 6.5 8.0 8.5 12.9 9.7 8.7 12.8 7.2 12.9 0.0 14.0 3.4 21.4 11.7 10.7 98.9 15.5 11.4 13.4 11.4 5.5 7.7 8.7 11.1 8.9 24.5 16.3 1.3 8.8 8.9 11.4 9.5 8.4 9.2 15.3 8.2 7.2 9.8 56.1 7.2 9.5 12.4 9.4 7.0 7.3 0.0 9.0 9.6 11.0 8.0 6.4 5.7 11.4 14.2 6.0 10.7 11.1 0.0 8.8 10.0 10.1 6.8 8.0 5.8 19.8 4.4 6.5 15.1 12.6 GOT2 "KAT4, KATIV, KYAT4, mitAAT" ENSG00000125166 "Glutamic-oxaloacetic transaminase 2" P00505 16 58707131-58734342 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Lipid transport, Transport" "Aminotransferase, Transferase" "Cancer-related genes, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 698.4;tongue: 726.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 341.9;Hepatocytes: 176.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018139, HPA058537" Enhanced "Intracellular and membrane" NA NA 2800000 "Cluster 13: T-cells - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA018139: AB_1849903, HPA058537: " "unprognostic (1.50e-2)" "unprognostic (4.79e-2)" "unprognostic (2.73e-3)" "unprognostic (2.63e-3)" "unprognostic (3.02e-2)" "prognostic unfavorable (1.61e-4)" "prognostic favorable (5.75e-5)" "unprognostic (1.12e-2)" "unprognostic (3.19e-1)" "unprognostic (3.72e-2)" "unprognostic (2.27e-1)" "unprognostic (3.00e-1)" "prognostic favorable (2.90e-9)" "unprognostic (1.16e-1)" "unprognostic (1.48e-1)" "unprognostic (5.56e-2)" "unprognostic (2.22e-1)" 19.6 73.9 52.4 27.4 55.9 21.1 36.3 62.5 66.9 34.1 129.4 57.6 37.4 36.5 66.3 66.9 46.7 24.1 313.2 57.9 59.3 88.0 321.4 25.2 35.6 60.6 51.0 29.4 33.2 98.6 46.7 24.7 62.5 59.0 65.0 91.4 47.7 65.7 698.4 41.1 35.7 46.7 50.1 28.5 54.9 28.9 58.7 35.9 42.6 726.8 57.0 57.0 45.1 61.0 137.2 182.4 93.8 114.8 66.6 59.8 122.0 101.4 108.8 197.6 107.7 158.9 120.1 302.3 117.3 114.6 86.5 195.5 203.2 199.2 250.1 83.1 182.0 81.4 92.1 179.3 84.2 132.3 71.9 58.4 110.9 125.2 108.2 112.4 201.8 141.9 167.0 30.6 102.2 122.5 164.0 128.0 127.7 90.8 338.0 177.8 142.7 291.1 187.9 197.7 148.2 107.6 195.2 208.5 74.8 84.2 105.5 42.7 82.3 71.4 129.3 56.2 132.4 69.9 68.6 247.4 76.7 130.9 73.8 4.6 20.6 7.4 28.3 16.9 43.7 26.5 33.1 34.1 34.7 22.3 30.1 28.4 1.8 30.2 18.4 30.0 48.7 31.2 52.4 55.9 62.5 66.9 57.9 59.3 60.6 51.0 62.5 50.1 58.7 61.0 15.1 9.6 15.8 11.8 19.8 32.0 37.0 39.4 34.1 34.5 27.5 16.3 341.9 22.8 22.5 36.8 77.2 42.6 11.8 42.6 56.7 50.8 4.0 30.4 20.0 23.8 20.5 39.3 24.7 42.5 38.8 21.1 30.1 25.4 14.5 37.5 23.2 176.1 39.1 20.2 27.1 33.5 26.4 17.0 15.1 8.1 18.0 13.5 24.9 5.6 12.7 16.1 8.2 11.6 17.6 40.3 13.3 22.6 39.2 38.2 27.6 63.2 17.5 48.9 0.0 15.2 24.0 11.9 15.0 68.9 30.0 23.7 17.4 36.4 54.4 69.6 GPAM "GPAT1, KIAA1560, MGC26846" ENSG00000119927 "Glycerol-3-phosphate acyltransferase, mitochondrial" Q9HCL2 10 112149865-112215377 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 305.7;liver: 144.1" "Cell type enhanced" "Detected in many" "Astrocytes: 90.8;Hepatocytes: 184.5;Horizontal cells: 45.4" "Cancer enriched" "Detected in all" 5 "liver cancer: 20.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "ASC diff: 250.3;Hep G2: 71.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046339, HPA060090" Approved Approved Mitochondria NA NA "Cluster 24: B-cells - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" Mitochondria "HPA046339: AB_2679627, HPA060090: AB_2684202" "unprognostic (1.82e-1)" "unprognostic (6.28e-2)" "unprognostic (1.13e-1)" "unprognostic (1.30e-1)" "unprognostic (6.80e-2)" "unprognostic (8.75e-2)" "unprognostic (1.40e-2)" "unprognostic (2.16e-2)" "unprognostic (4.59e-1)" "unprognostic (4.80e-1)" "unprognostic (2.37e-2)" "unprognostic (5.44e-2)" "prognostic favorable (4.54e-6)" "unprognostic (2.84e-1)" "unprognostic (4.41e-2)" "unprognostic (2.52e-2)" "unprognostic (1.37e-1)" 305.7 33.9 14.9 4.8 17.1 3.4 67.7 12.2 14.0 3.0 6.9 6.4 4.0 4.2 75.1 2.9 3.1 6.0 12.3 12.4 13.0 4.4 144.1 4.1 4.6 12.9 16.0 5.3 5.0 4.3 2.1 3.0 12.1 3.9 4.7 5.1 17.2 5.3 8.3 3.2 6.1 4.9 11.5 2.9 4.9 5.6 15.7 3.6 12.4 8.8 4.3 4.8 2.6 10.5 9.9 7.4 9.7 12.9 250.3 9.1 12.7 9.2 10.5 6.6 5.1 17.3 5.7 6.9 5.0 6.5 6.1 12.3 15.5 7.9 12.3 5.0 8.4 6.4 7.9 71.8 7.7 11.2 3.4 43.8 13.1 11.7 23.6 49.7 5.8 9.7 8.5 6.1 7.7 5.6 9.6 8.8 8.1 5.6 10.1 9.7 25.4 5.1 4.3 6.8 4.1 12.1 12.8 6.1 14.5 8.9 6.3 4.0 4.4 7.5 4.6 9.4 14.8 6.1 7.3 14.3 8.8 9.8 5.8 0.0 0.3 0.1 0.7 0.4 0.9 0.5 0.5 0.5 0.4 1.1 0.5 0.9 0.0 0.3 0.3 0.6 0.6 0.3 14.9 17.1 12.2 14.0 12.4 13.0 12.9 16.0 12.1 11.5 15.7 10.5 9.1 9.6 27.1 90.8 5.2 0.4 0.8 1.6 4.6 5.3 8.1 8.4 18.9 20.0 4.3 5.5 10.4 5.2 4.3 1.7 1.9 2.7 0.5 5.1 10.0 5.0 1.2 12.2 8.2 3.3 2.9 5.1 3.6 4.2 2.5 12.7 6.4 184.5 3.1 45.4 9.4 3.0 0.0 9.3 1.0 0.9 5.3 1.9 1.8 10.3 1.4 6.1 3.1 10.1 10.1 3.4 2.7 12.0 6.4 1.1 3.7 3.3 4.7 9.1 6.6 4.3 6.6 4.0 3.2 5.4 0.1 1.9 3.3 8.6 5.0 0.6 GPC1 glypican ENSG00000063660 "Glypican 1" P35052 2 240435663-240468076 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 226.0" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 199.8;Syncytiotrophoblasts: 102.7;Urothelial cells: 110.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030571, HPA070449" Enhanced Supported "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 9500000 "Cluster 31: Skin - Epidermis development" "Cluster 17: WM-115 - Nervous system development" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane, Cytosol" "HPA030571: AB_10602322, HPA070449: " "unprognostic (1.22e-2)" "unprognostic (2.53e-2)" "prognostic unfavorable (5.78e-5)" "prognostic unfavorable (1.55e-4)" "unprognostic (1.95e-1)" "unprognostic (1.83e-3)" "prognostic unfavorable (2.44e-6)" "unprognostic (1.00e-2)" "unprognostic (2.15e-1)" "unprognostic (5.08e-3)" "unprognostic (2.28e-1)" "unprognostic (4.38e-1)" "unprognostic (1.91e-1)" "unprognostic (4.40e-2)" "unprognostic (2.92e-1)" "unprognostic (1.95e-2)" "unprognostic (2.12e-2)" 36.8 78.5 42.8 9.0 37.0 0.4 30.7 25.3 64.4 44.5 3.1 36.7 5.8 37.1 9.3 88.4 30.8 8.5 145.2 41.7 28.5 47.6 35.7 21.9 1.4 29.2 30.4 45.1 25.8 9.8 55.7 29.0 26.3 67.8 3.5 5.0 35.2 22.5 134.2 226.0 17.4 16.4 11.3 15.6 23.0 48.7 46.0 9.1 15.7 35.3 6.6 35.1 62.3 24.8 69.0 92.9 21.6 56.7 64.3 61.5 87.3 161.5 78.8 18.3 21.2 33.3 74.9 1.8 21.8 172.0 100.1 186.0 11.7 114.7 3.8 33.3 9.8 0.1 80.7 41.7 92.2 1.6 6.2 54.3 73.4 41.2 21.3 38.1 9.7 3.4 0.4 3.3 47.5 36.0 1.3 0.6 33.7 7.7 20.5 12.3 98.2 16.1 15.0 109.6 21.5 14.4 105.7 91.9 10.1 19.3 29.1 7.0 45.6 97.3 162.3 46.9 67.8 0.7 0.4 0.8 69.4 1.7 111.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 42.8 37.0 25.3 64.4 41.7 28.5 29.2 30.4 26.3 11.3 46.0 24.8 1.2 16.0 6.1 45.7 0.7 45.9 69.6 62.2 56.3 22.4 8.3 18.2 53.2 21.5 34.0 25.8 2.1 73.7 0.3 3.7 7.9 27.8 0.9 6.2 24.7 2.8 0.0 0.0 53.0 10.8 199.8 21.0 1.5 8.9 4.5 49.4 11.0 26.3 9.1 25.2 45.0 7.0 16.2 0.6 7.7 3.8 19.0 1.2 35.6 5.6 1.6 24.9 1.0 18.6 8.9 17.6 0.9 7.5 0.9 67.0 0.5 2.3 30.2 6.4 26.3 33.9 38.2 2.2 9.9 44.8 46.2 102.7 1.9 14.5 3.6 110.5 GPLD1 ENSG00000112293 "Glycosylphosphatidylinositol specific phospholipase D1" P80108 6 24424565-24495205 "Enzymes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 46.1" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 68.8;Excitatory neurons: 62.4;Hepatocytes: 66.8;Inhibitory neurons: 78.3;Oligodendrocyte precursor cells: 33.2" "Cancer enriched" "Detected in some" 11 "liver cancer: 6.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 7.6;U-698: 8.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008625, HPA012500" Uncertain "Secreted to blood" NA NA 103000000000 3100000000 "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB008625: AB_1621070, HPA012500: AB_1849931" "unprognostic (6.80e-3)" "unprognostic (2.27e-1)" "unprognostic (1.59e-1)" "unprognostic (4.81e-5)" "unprognostic (3.65e-1)" "unprognostic (1.02e-1)" "prognostic favorable (1.12e-4)" "unprognostic (6.37e-4)" "unprognostic (7.93e-2)" "unprognostic (2.86e-2)" "unprognostic (6.07e-4)" "unprognostic (2.68e-1)" "unprognostic (5.28e-4)" "unprognostic (2.20e-1)" "unprognostic (9.98e-2)" "unprognostic (3.73e-2)" "unprognostic (1.22e-1)" 4.2 0.9 2.0 0.6 1.7 0.9 1.3 7.6 4.7 1.1 0.1 1.0 0.5 1.6 1.7 1.1 0.9 0.6 0.5 1.3 2.4 0.6 46.1 0.9 0.9 1.8 1.9 1.2 0.6 2.5 1.7 0.2 1.9 1.8 0.6 6.2 0.4 4.8 1.7 8.6 0.4 1.4 0.6 0.6 0.7 1.4 1.4 5.1 2.4 0.6 1.3 1.1 1.5 2.1 0.5 0.7 0.8 1.2 0.0 0.0 2.0 0.1 0.2 0.2 0.1 3.5 0.1 7.6 0.8 0.1 0.2 0.1 1.2 0.2 0.1 0.9 2.1 1.1 0.9 3.2 0.0 1.4 0.2 0.0 0.1 0.0 0.0 0.8 0.0 1.8 0.5 0.3 0.1 0.5 0.7 0.5 2.9 0.5 0.3 1.4 0.2 0.1 0.4 3.4 2.0 2.3 0.9 0.1 0.4 0.6 0.4 0.3 0.1 0.7 0.9 0.1 1.0 2.4 3.4 8.1 0.1 0.3 0.3 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.3 0.1 0.1 0.0 0.2 0.1 0.0 2.0 1.7 7.6 4.7 1.3 2.4 1.8 1.9 1.9 0.6 1.4 2.1 0.4 0.0 3.7 24.8 1.1 0.0 0.7 2.8 0.6 19.6 0.7 0.4 11.6 0.0 1.7 1.8 68.8 0.3 1.6 0.1 0.0 0.4 3.5 0.5 0.6 1.2 1.8 7.4 62.4 0.4 0.3 1.3 0.0 0.3 0.0 2.1 1.4 66.8 0.1 15.2 78.3 0.3 0.0 1.3 0.0 3.4 3.1 0.1 0.0 9.4 0.1 4.0 3.1 33.2 3.1 0.1 0.1 3.4 3.1 0.3 0.1 0.5 1.1 10.9 0.0 3.6 1.4 0.5 5.8 0.3 0.6 0.0 0.5 0.9 0.5 2.6 GPN1 "ATPBD1A, MBDIN, NTPBP, RPAP4, XAB1" ENSG00000198522 "GPN-loop GTPase 1" Q9HCN4 2 27628247-27651511 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 86.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036793, HPA036794, CAB037303" Uncertain Supported Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Cytosol" Mitochondria "CAB037303: AB_477173, HPA036793: AB_2675318, HPA036794: AB_10672230" "unprognostic (9.42e-2)" "unprognostic (1.44e-1)" "unprognostic (5.64e-2)" "prognostic unfavorable (2.88e-5)" "unprognostic (2.57e-1)" "unprognostic (1.63e-3)" "prognostic unfavorable (1.71e-5)" "unprognostic (3.50e-2)" "unprognostic (8.27e-3)" "unprognostic (8.93e-2)" "unprognostic (4.05e-3)" "unprognostic (2.34e-1)" "unprognostic (1.21e-2)" "unprognostic (2.51e-1)" "unprognostic (1.13e-1)" "unprognostic (2.01e-1)" "unprognostic (1.72e-1)" 22.8 22.8 19.3 20.3 19.8 34.1 26.4 19.9 26.1 18.1 19.5 22.7 19.9 19.1 19.9 25.5 21.0 18.6 21.3 19.4 21.6 26.3 24.6 18.6 28.7 22.5 22.6 18.4 22.8 25.9 16.6 26.5 21.8 17.7 25.6 24.9 21.5 16.9 32.4 24.8 19.6 22.4 19.6 22.2 20.6 25.5 21.9 30.1 22.8 27.2 30.3 24.0 19.5 21.2 94.6 53.3 48.8 35.4 44.3 44.8 48.7 52.0 50.5 70.7 52.1 58.0 47.4 58.8 49.2 56.4 65.4 39.5 67.6 63.4 71.5 55.4 47.6 66.8 38.3 70.7 57.3 100.0 33.7 46.7 54.8 72.6 67.1 49.4 75.2 51.5 84.7 53.5 84.1 54.2 60.3 75.1 83.4 70.9 50.7 60.2 144.4 61.0 57.9 53.5 42.9 67.6 57.2 61.5 58.4 44.7 37.1 56.0 62.9 61.5 91.1 30.9 122.7 60.8 71.8 156.9 88.0 85.0 51.8 92.4 61.3 55.1 79.1 71.6 86.0 74.6 72.2 92.0 89.7 68.7 63.8 78.2 9.3 106.1 72.1 46.8 79.2 82.3 19.3 19.8 19.9 26.1 19.4 21.6 22.5 22.6 21.8 19.6 21.9 21.2 17.6 12.8 10.4 2.3 18.7 21.7 21.7 28.2 10.8 9.2 14.8 11.8 11.8 14.3 19.7 14.7 4.2 43.5 28.8 9.5 23.5 46.4 86.3 20.5 14.1 17.3 17.4 18.7 6.6 36.3 46.2 14.3 9.7 21.7 24.7 17.7 17.5 10.2 33.4 11.8 6.6 13.0 20.3 20.1 26.8 76.0 14.9 17.6 23.2 2.8 28.9 15.0 27.8 5.0 5.0 46.3 13.5 10.9 11.2 20.1 16.2 20.8 14.3 10.9 13.1 13.2 19.0 36.6 23.4 13.6 18.6 33.1 31.0 20.2 20.0 18.9 GPR137C "DKFZp762F0713, TM7SF1L2" ENSG00000180998 "G protein-coupled receptor 137C" Q8N3F9 14 52552836-52637713 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "brain: 14.6;epididymis: 8.1;retina: 17.3" "Group enriched" "Detected in many" 5 "Excitatory neurons: 85.5;Inhibitory neurons: 125.4;Oligodendrocyte precursor cells: 101.6;Oligodendrocytes: 137.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 9 "NK-cells: 1.5;T-cells: 1.4" "Cell line enhanced" "Detected in many" "SH-SY5Y: 9.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003640, HPA030763" Uncertain Approved Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA003640: AB_2667025, HPA030763: AB_10602352" "unprognostic (1.39e-1)" "unprognostic (1.45e-1)" "unprognostic (1.23e-1)" "unprognostic (6.84e-2)" "unprognostic (8.50e-3)" "unprognostic (7.34e-3)" "unprognostic (5.95e-3)" "unprognostic (2.32e-2)" "unprognostic (4.41e-2)" "unprognostic (8.42e-4)" "unprognostic (2.20e-2)" "unprognostic (1.04e-1)" "unprognostic (7.88e-2)" "unprognostic (4.08e-1)" "unprognostic (1.38e-2)" "unprognostic (2.83e-1)" "unprognostic (2.60e-1)" 0.5 0.7 5.3 0.2 3.8 0.9 0.5 14.6 7.2 0.6 0.0 0.4 0.7 0.8 8.1 0.4 0.3 1.1 1.0 4.0 5.5 0.4 0.6 0.8 0.4 5.9 5.9 0.7 0.2 0.4 1.5 0.4 5.0 0.7 0.4 17.3 0.2 0.4 0.5 0.2 0.3 0.4 2.4 1.0 0.4 2.9 8.4 0.3 0.6 0.6 0.1 0.4 0.3 7.7 0.8 0.3 6.6 6.4 1.7 0.6 2.7 3.3 2.2 3.2 7.8 0.9 1.4 0.2 1.9 2.2 6.5 1.5 2.5 0.5 4.5 0.4 1.7 0.3 1.5 0.4 0.1 0.1 1.1 0.4 0.0 2.8 0.2 0.6 1.5 1.1 0.9 2.3 4.4 3.8 0.1 0.6 1.1 0.4 4.1 1.2 4.3 0.3 1.0 4.8 7.4 9.1 1.3 0.2 0.1 2.7 4.4 0.0 0.0 6.8 7.6 5.5 2.3 0.4 1.6 0.8 1.5 0.1 1.9 0.0 0.0 0.0 1.0 0.0 1.4 0.0 0.5 1.4 0.0 0.0 0.3 0.5 0.1 1.5 0.1 0.0 0.5 0.2 5.3 3.8 14.6 7.2 4.0 5.5 5.9 5.9 5.0 2.4 8.4 7.7 2.8 0.0 1.3 20.2 0.7 0.6 0.7 0.1 2.2 22.4 1.4 1.4 2.5 1.5 0.1 0.0 2.1 0.3 0.4 0.4 0.0 0.3 2.3 3.4 1.6 3.8 1.2 0.0 85.5 0.2 0.3 1.9 1.1 6.2 0.0 5.6 2.2 0.5 0.5 6.7 125.4 0.7 0.0 2.2 0.8 1.5 0.6 0.9 1.8 21.5 0.2 5.4 1.0 101.6 137.4 0.0 0.0 0.7 1.0 1.8 0.1 0.2 0.1 20.2 0.0 1.1 1.7 6.9 5.1 1.3 0.9 0.1 1.2 1.2 0.1 0.5 GPR146 PGR8 ENSG00000164849 "G protein-coupled receptor 146" Q96CH1 7 1044546-1059261 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "adipose tissue: 47.9" "Cell type enhanced" "Detected in many" "Adipocytes: 96.3;Endothelial cells: 45.3;Extravillous trophoblasts: 243.2;Syncytiotrophoblasts: 82.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "eosinophil: 95.2;naive CD4 T-cell: 25.6" "Group enriched" "Detected in many" 4 "granulocytes: 95.2;T-cells: 25.6" "Cell line enhanced" "Detected in many" "BEWO: 23.0;NB-4: 7.1" "Low region specificity" "Detected in all" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "unprognostic (3.39e-2)" "unprognostic (7.83e-2)" "unprognostic (6.27e-4)" "unprognostic (5.51e-3)" "unprognostic (1.78e-1)" "unprognostic (2.33e-1)" "unprognostic (2.30e-1)" "unprognostic (2.69e-1)" "unprognostic (2.99e-2)" "unprognostic (3.48e-3)" "unprognostic (2.51e-2)" "unprognostic (1.70e-1)" "unprognostic (1.14e-1)" "unprognostic (3.27e-3)" "unprognostic (1.41e-1)" "unprognostic (4.19e-2)" "unprognostic (1.03e-2)" 47.9 2.6 16.9 2.0 17.2 9.0 41.8 17.0 20.9 10.0 22.1 14.1 2.8 13.2 2.8 4.7 12.3 7.5 13.2 13.6 15.4 5.3 20.4 24.9 4.1 18.6 18.4 7.4 5.9 1.6 3.4 10.2 18.7 7.2 1.0 3.6 9.6 5.5 10.7 11.2 8.1 3.5 16.6 6.7 12.9 2.6 21.8 1.7 11.5 8.8 1.2 13.2 8.7 17.3 1.2 1.0 0.4 1.0 1.3 0.3 23.0 0.1 0.9 0.2 1.1 0.8 1.1 0.4 0.7 0.1 3.5 0.8 0.0 0.3 0.1 0.8 0.9 1.7 0.7 1.9 1.5 0.1 0.2 0.5 0.0 0.7 0.0 2.4 1.7 0.6 1.1 1.2 0.2 0.7 0.0 7.1 1.6 1.3 0.6 5.5 0.0 1.5 0.3 0.1 1.2 1.7 1.8 0.2 2.0 0.9 1.1 2.2 0.5 1.0 1.1 1.6 0.8 1.9 2.1 0.1 6.1 2.2 2.1 0.0 0.2 95.2 0.6 0.1 1.2 0.0 8.4 0.7 1.7 0.1 25.6 4.8 0.1 1.3 0.3 14.3 14.5 4.3 16.9 17.2 17.0 20.9 13.6 15.4 18.6 18.4 18.7 16.6 21.8 17.3 96.3 0.0 2.8 7.2 3.3 1.8 0.8 1.8 1.2 3.7 7.6 3.4 0.3 1.5 2.1 1.8 0.0 9.3 1.4 0.3 1.9 1.0 0.1 3.2 0.4 45.3 4.2 30.5 0.9 0.6 243.2 4.8 2.0 3.7 2.5 1.7 16.4 21.3 10.9 3.3 1.4 0.3 2.0 0.6 6.1 1.1 3.1 1.7 3.6 3.7 0.2 21.2 2.1 4.5 1.7 0.7 0.3 3.4 0.9 0.7 0.8 3.4 0.0 5.7 0.0 2.3 1.4 0.5 1.5 0.4 2.3 82.4 2.5 0.9 1.0 0.4 GPR20 ENSG00000204882 "G protein-coupled receptor 20" Q99678 8 141356470-141367286 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enriched" "Detected in some" 4 "Sertoli cells: 72.3" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 18 "intermediate monocyte: 2.6;non-classical monocyte: 4.3" "Lineage enriched" "Detected in single" 22 "monocytes: 4.3" "Cell line enriched" "Detected in single" 6 "EFO-21: 4.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA071337 Supported "Plasma membrane,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 38: EFO-21 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" Cytosol "HPA071337: " "unprognostic (4.47e-2)" "unprognostic (2.64e-3)" "unprognostic (5.18e-2)" "unprognostic (2.00e-2)" "unprognostic (7.47e-2)" "unprognostic (2.28e-1)" "unprognostic (4.43e-2)" "unprognostic (5.01e-2)" "unprognostic (3.54e-1)" "unprognostic (2.13e-2)" "unprognostic (1.57e-1)" "unprognostic (1.13e-1)" "unprognostic (1.07e-2)" "unprognostic (7.41e-2)" "unprognostic (5.50e-2)" "unprognostic (6.23e-2)" "unprognostic (4.07e-1)" 0.8 0.2 0.0 0.2 0.0 0.0 0.6 0.0 0.4 2.0 0.0 1.4 0.4 1.9 0.7 0.6 1.5 0.7 1.1 0.0 0.0 0.6 0.2 1.5 0.0 0.0 0.0 1.2 0.2 0.1 0.2 1.2 0.1 0.9 0.3 0.0 0.2 0.8 0.3 0.4 2.1 1.8 0.0 0.2 1.7 0.1 0.0 0.0 0.5 0.4 0.0 0.7 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.1 0.1 0.4 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.3 0.0 0.0 0.7 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 1.9 0.0 0.2 1.8 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 72.3 0.3 16.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 GPR34 ENSG00000171659 "G protein-coupled receptor 34" Q9UPC5 X 41688973-41697275 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 42.7" "Cell type enhanced" "Detected in many" "Hofbauer cells: 251.4;Kupffer cells: 173.3;Macrophages: 100.6;Microglial cells: 54.4" "Cancer enhanced" "Detected in all" "glioma: 26.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "basophil: 339.6;eosinophil: 117.9" "Lineage enriched" "Detected in many" 24 "granulocytes: 339.6" "Cell line enhanced" "Detected in single" "HMC-1: 1.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010668, CAB025490" Uncertain Approved Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Cytosol "CAB025490: , HPA010668: AB_1849294" "unprognostic (1.26e-2)" "unprognostic (1.08e-1)" "unprognostic (1.43e-2)" "unprognostic (1.44e-2)" "unprognostic (1.20e-1)" "unprognostic (3.74e-2)" "unprognostic (5.83e-3)" "unprognostic (5.13e-2)" "unprognostic (1.59e-2)" "unprognostic (9.81e-3)" "unprognostic (7.19e-2)" "unprognostic (1.74e-1)" "unprognostic (3.96e-1)" "unprognostic (2.72e-3)" "unprognostic (1.14e-1)" "unprognostic (1.88e-3)" "unprognostic (3.18e-2)" 28.2 17.1 5.2 15.1 5.2 0.9 21.5 6.1 5.8 14.0 5.6 12.0 6.5 6.7 2.7 8.2 7.8 17.0 8.3 5.0 7.6 5.0 8.5 10.9 20.0 10.6 7.9 7.3 5.4 5.3 1.4 42.7 11.4 3.2 13.1 0.6 3.6 8.8 0.8 1.0 14.6 16.3 9.9 15.6 7.8 2.7 9.7 6.9 3.7 4.6 16.7 13.3 1.7 18.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.0 339.6 9.7 117.9 0.0 12.9 0.4 1.5 0.4 0.1 2.0 1.2 0.1 0.3 1.1 14.3 7.0 0.3 0.6 2.8 5.2 5.2 6.1 5.8 5.0 7.6 10.6 7.9 11.4 9.9 9.7 18.8 0.9 0.0 2.8 1.0 2.0 0.6 0.2 0.0 0.0 0.0 0.5 2.3 1.2 0.0 0.0 0.0 0.0 1.4 0.4 0.0 0.0 0.0 0.6 0.1 0.1 5.0 1.2 0.4 0.7 0.0 1.6 1.0 0.5 0.0 37.3 0.0 2.9 0.8 251.4 0.0 0.9 0.0 0.0 173.3 13.6 1.9 0.9 100.6 1.8 54.4 7.1 0.1 1.0 3.5 0.0 0.0 0.0 0.4 0.6 0.1 0.0 0.1 0.0 0.8 19.7 0.6 0.3 0.0 0.2 0.4 1.0 2.5 7.2 0.1 0.1 0.0 GPR45 "PSP24, PSP24A" ENSG00000135973 "G protein-coupled receptor 45" Q9Y5Y3 2 105241743-105243467 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 2.2" "Group enriched" "Detected in some" 51 "Early spermatids: 4.2;Late spermatids: 6.1" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "BEWO: 1.3;U-2 OS: 4.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA055940 Uncertain NA NA "Cluster 65: Brain - Ion transport" "Cluster 9: U-2 OS - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" "HPA055940: AB_2682977" "unprognostic (3.80e-3)" "unprognostic (5.92e-2)" "unprognostic (2.19e-3)" "unprognostic (4.71e-1)" "unprognostic (1.01e-1)" "unprognostic (2.17e-1)" "unprognostic (6.87e-2)" "unprognostic (2.21e-1)" "unprognostic (1.13e-1)" "unprognostic (3.96e-1)" "unprognostic (1.61e-3)" "unprognostic (1.11e-2)" "unprognostic (3.13e-4)" "unprognostic (2.25e-1)" "unprognostic (2.76e-1)" "unprognostic (1.39e-1)" "unprognostic (3.99e-2)" 0.0 0.0 0.8 0.0 0.4 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.5 0.1 0.1 0.0 0.0 0.6 0.9 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.7 2.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.1 0.0 0.0 4.2 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.4 0.0 0.8 0.6 1.5 0.6 0.9 0.9 0.5 2.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GPRC5B RAIG-2 ENSG00000167191 "G protein-coupled receptor class C group 5 member B" Q9NZH0 16 19856691-19886167 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 490.3" "Cell type enhanced" "Detected in many" "Early spermatids: 197.7;Late spermatids: 269.9;Oligodendrocytes: 171.0" "Cancer enhanced" "Detected in all" "glioma: 52.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD4 T-cell: 2.8" "Lineage enhanced" "Detected in single" "T-cells: 2.8" "Cell line enhanced" "Detected in many" "EFO-21: 92.5;HHSteC: 60.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015247 Enhanced Supported Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 32: T-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 38: EFO-21 - Unknown function" "Cluster 34: Spermatids - Unknown function" Vesicles "Nucleoplasm, Nucleoli" "HPA015247: AB_1849323" "unprognostic (1.26e-1)" "unprognostic (1.32e-1)" "prognostic unfavorable (9.27e-5)" "unprognostic (2.60e-3)" "unprognostic (3.28e-1)" "unprognostic (2.46e-1)" "unprognostic (3.97e-2)" "unprognostic (5.70e-2)" "unprognostic (1.42e-1)" "unprognostic (2.26e-2)" "unprognostic (2.76e-2)" "unprognostic (1.27e-1)" "prognostic favorable (6.30e-4)" "unprognostic (4.73e-2)" "unprognostic (1.06e-1)" "unprognostic (4.42e-3)" "unprognostic (6.78e-3)" 25.3 7.0 249.1 4.4 428.3 0.1 19.6 365.2 263.4 12.8 13.1 8.1 5.7 13.1 14.8 8.1 20.1 15.3 40.7 245.8 278.4 22.4 3.2 5.8 7.8 379.4 327.1 22.6 21.7 45.9 14.1 15.7 333.0 9.6 2.4 17.4 40.1 17.7 72.7 7.5 11.1 7.5 262.7 2.5 41.3 34.0 315.0 3.2 13.8 73.8 3.4 12.8 8.6 490.3 1.2 29.9 29.0 5.2 29.3 2.0 5.3 0.3 7.4 2.9 1.8 28.0 1.0 0.0 92.5 1.0 18.9 1.6 21.6 0.2 1.7 0.2 8.6 0.0 0.1 0.0 60.3 0.0 0.0 2.5 0.0 4.9 0.0 7.9 14.3 0.7 6.6 0.6 6.7 1.5 0.1 0.1 31.8 0.0 15.6 8.9 0.0 0.2 1.1 13.8 22.9 1.9 3.6 1.9 27.2 9.1 0.1 0.6 2.9 0.0 3.5 14.4 0.8 0.4 0.1 0.3 1.4 0.3 1.8 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.7 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.1 0.0 0.0 0.5 249.1 428.3 365.2 263.4 245.8 278.4 379.4 327.1 333.0 262.7 315.0 490.3 71.4 0.0 3.0 75.4 1.2 1.3 5.3 2.6 9.1 30.7 22.5 16.3 15.7 40.0 7.2 31.3 0.0 5.0 0.3 0.2 1.9 65.3 197.7 4.1 20.7 44.8 0.0 0.0 2.4 64.5 1.4 14.8 31.6 13.7 0.0 0.4 9.3 0.2 4.1 0.0 13.5 0.0 38.7 1.6 2.6 269.9 23.9 2.2 16.0 7.5 1.0 24.8 0.0 51.8 171.0 72.8 0.0 26.7 1.3 12.3 0.0 0.3 3.3 6.0 13.1 3.3 13.0 4.9 1.6 2.4 1.7 2.5 0.8 7.0 0.2 1.6 GPSM1 "AGS3, DKFZP727I051" ENSG00000160360 "G protein signaling modulator 1" Q86YR5 9 136327476-136359605 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 26.1;Bipolar cells: 37.2;Cone photoreceptor cells: 22.9;Muller glia cells: 36.0;Rod photoreceptor cells: 43.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "REH: 82.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042199, HPA060736" Approved Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 14: REH - Unknown function" "Cluster 5: Muller glia cells - Visual perception" "Golgi apparatus" Nucleoplasm "HPA042199: AB_10959329, HPA060736: " "unprognostic (1.73e-2)" "unprognostic (1.35e-1)" "prognostic unfavorable (6.07e-4)" "unprognostic (4.07e-3)" "unprognostic (3.44e-1)" "unprognostic (1.29e-1)" "unprognostic (1.19e-1)" "unprognostic (1.37e-2)" "unprognostic (2.03e-2)" "unprognostic (1.48e-1)" "unprognostic (5.96e-3)" "unprognostic (3.37e-2)" "prognostic unfavorable (3.30e-4)" "unprognostic (4.66e-2)" "unprognostic (1.84e-1)" "unprognostic (6.42e-2)" "unprognostic (7.48e-2)" 13.0 21.7 32.6 4.2 30.6 4.5 12.4 50.9 44.4 38.7 12.7 18.5 3.3 23.3 7.2 6.0 20.3 4.7 74.9 30.5 26.7 19.6 4.7 35.4 2.1 34.9 29.8 38.1 42.3 3.8 19.7 6.6 28.7 30.6 1.2 18.7 8.6 5.9 2.7 17.0 9.3 4.0 25.1 19.9 17.2 29.4 28.6 2.0 12.4 0.7 1.1 15.1 24.4 28.6 3.9 6.2 14.5 25.4 8.1 14.1 12.1 43.0 17.6 11.8 6.4 12.5 4.1 0.0 17.8 26.0 9.9 2.9 2.3 8.8 2.6 35.1 25.5 5.0 23.4 2.3 34.7 0.3 6.1 23.0 5.8 10.8 6.2 14.5 12.0 5.9 13.5 0.2 7.9 14.2 2.4 4.9 15.5 1.4 22.5 82.3 26.2 12.7 3.2 2.8 35.6 44.4 8.0 1.0 13.7 5.6 17.7 8.6 20.0 21.7 17.5 25.7 8.9 7.6 0.3 0.1 13.0 0.0 21.0 0.0 0.0 0.0 0.1 0.4 0.1 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.1 32.6 30.6 50.9 44.4 30.5 26.7 34.9 29.8 28.7 25.1 28.6 28.6 4.7 3.2 3.3 26.1 0.6 4.2 2.3 0.8 0.0 37.2 2.5 5.8 12.4 0.0 0.8 0.0 22.9 0.6 1.6 0.0 11.7 3.3 0.6 2.7 18.1 3.9 1.8 2.5 9.0 1.9 0.8 9.1 0.5 5.5 5.7 14.2 3.6 0.0 1.1 10.1 11.6 0.0 0.0 0.3 2.8 1.3 10.5 1.5 8.8 6.5 0.5 36.0 0.0 9.5 10.4 7.3 0.0 9.4 0.3 10.6 0.0 0.1 0.6 43.0 0.0 5.8 6.0 0.4 3.7 0.1 3.3 0.3 1.1 3.3 0.0 4.0 GPX2 GSHPX-GI ENSG00000176153 "Glutathione peroxidase 2" P18283 14 64939152-64942905 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Oxidoreductase, Peroxidase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 497.7;intestine: 453.8;liver: 634.0;stomach 1: 374.6;urinary bladder: 350.5" "Cell type enhanced" "Detected in many" "Cholangiocytes: 386.1;Distal enterocytes: 436.6;Gastric mucus-secreting cells: 912.3;Hepatocytes: 753.4;Intestinal goblet cells: 438.6;Paneth cells: 463.0;Undifferentiated cells: 776.8;Urothelial cells: 1062.0" "Cancer enhanced" "Detected in many" "colorectal cancer: 493.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "OE19: 4748.8" "Region enhanced" "Detected in single" "pons and medulla: 1.2" "Low region specificity" "Detected in some" HPA003545 Enhanced Approved Nucleoplasm,Cytosol NA NA 82000 "Cluster 48: NK-cells - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Cytosol "HPA003545: AB_10962695" "unprognostic (3.54e-1)" "unprognostic (1.08e-2)" "unprognostic (1.51e-1)" "unprognostic (1.90e-3)" "unprognostic (4.75e-3)" "prognostic unfavorable (5.10e-4)" "unprognostic (2.96e-2)" "unprognostic (2.93e-2)" "unprognostic (7.87e-2)" "unprognostic (1.54e-2)" "unprognostic (8.45e-2)" "unprognostic (1.44e-1)" "unprognostic (2.77e-2)" "unprognostic (4.39e-2)" "unprognostic (3.39e-2)" "unprognostic (6.66e-4)" "unprognostic (1.73e-2)" 1.9 0.2 0.1 53.8 0.3 0.3 5.3 0.5 0.3 23.5 0.1 333.5 96.7 0.7 1.7 187.7 4.9 497.7 0.3 0.2 0.5 30.6 634.0 2.6 0.1 0.4 0.2 0.2 24.5 0.0 1.2 0.2 0.4 43.3 453.8 0.0 71.8 24.9 0.3 25.4 175.7 9.7 0.1 0.6 374.6 2.5 0.3 3.3 0.5 0.0 1.2 350.5 108.2 0.7 0.0 1152.6 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 36.9 9.6 0.0 6.0 0.0 1.9 303.7 0.6 4.8 0.0 0.2 0.1 0.1 1.1 1048.6 0.0 0.1 0.4 0.0 9.7 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 5.6 0.6 0.3 1.3 4748.8 0.2 0.5 0.2 0.2 0.1 727.5 324.2 0.2 0.1 13.4 0.0 0.6 0.5 0.0 0.0 0.0 0.8 0.1 0.3 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.3 0.5 0.3 0.2 0.5 0.4 0.2 0.4 0.1 0.3 0.7 0.1 0.0 0.0 0.3 6.9 9.9 169.4 104.5 42.1 0.2 0.6 4.1 0.4 386.1 17.1 23.9 0.0 0.1 0.0 436.6 11.7 272.8 13.8 3.8 0.5 3.5 115.2 50.8 0.2 260.6 0.1 2.1 912.3 2.8 13.4 0.1 17.5 753.4 0.0 0.0 0.2 438.6 36.7 26.1 0.8 66.6 0.9 3.5 0.0 1.9 3.2 0.0 0.0 0.0 0.4 163.7 463.0 0.0 2.4 100.7 68.1 31.4 9.0 0.7 0.0 0.0 3.6 0.4 0.0 315.5 9.7 0.0 5.9 0.1 776.8 1062.0 GPX4 "MCSP, PHGPx" ENSG00000167468 "Glutathione peroxidase 4" P36969 19 1103926-1106791 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Developmental protein, Oxidoreductase, Peroxidase" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Late spermatids: 18580.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008630, HPA047224, HPA058546" Enhanced Approved Nucleoplasm,Mitochondria "Intracellular and membrane" NA NA 150000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 78: Testis - Spermatogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Mitochondria" "CAB008630: AB_1616685, HPA047224: AB_2679990, HPA058546: AB_2683749" "unprognostic (8.42e-3)" "prognostic favorable (7.18e-4)" "unprognostic (8.14e-3)" "prognostic favorable (1.84e-5)" "unprognostic (1.00e-1)" "unprognostic (8.72e-2)" "unprognostic (2.53e-3)" "unprognostic (8.49e-2)" "unprognostic (2.69e-2)" "unprognostic (1.47e-1)" "prognostic favorable (7.72e-4)" "unprognostic (1.29e-1)" "prognostic favorable (8.61e-4)" "unprognostic (1.61e-2)" "unprognostic (2.20e-1)" "unprognostic (6.67e-3)" "unprognostic (2.96e-2)" 927.8 535.3 415.1 127.4 428.7 178.0 733.3 440.7 519.1 280.8 478.7 249.0 259.0 188.4 318.9 220.4 199.2 196.6 426.0 419.2 450.3 536.5 687.8 307.9 216.4 430.9 448.3 260.3 157.9 285.5 398.4 147.2 454.1 322.1 110.9 167.5 304.9 193.8 672.3 290.4 236.2 87.9 418.2 213.2 219.0 1403.5 444.0 158.7 291.5 399.7 182.5 319.0 245.2 429.1 258.1 286.8 405.8 863.0 1202.1 706.0 449.3 199.3 713.5 371.1 375.9 590.5 339.8 92.8 211.8 405.8 313.5 283.1 239.7 289.3 180.5 522.3 436.5 175.0 246.9 849.2 697.4 207.6 269.4 707.3 432.1 188.3 314.7 665.9 527.1 317.5 249.4 225.7 311.1 660.4 353.8 354.9 386.2 569.7 458.9 482.8 55.3 271.3 408.9 629.9 348.3 220.6 390.5 366.1 422.1 246.7 358.1 498.0 450.9 392.3 257.4 680.6 254.6 786.5 582.0 224.3 369.4 412.2 230.9 578.9 539.6 564.4 219.8 405.4 256.9 352.7 319.7 230.7 404.0 309.9 339.4 245.0 265.1 196.6 462.2 278.8 310.3 841.7 415.1 428.7 440.7 519.1 419.2 450.3 430.9 448.3 454.1 418.2 444.0 429.1 415.9 179.5 189.7 21.2 281.7 510.0 525.8 1188.1 512.2 332.2 845.1 868.2 264.6 316.0 600.6 472.6 98.0 562.5 231.3 479.1 1592.6 515.8 4209.7 546.8 326.3 268.7 397.1 215.0 24.5 368.7 1327.3 536.1 99.9 442.3 346.1 242.6 322.0 826.2 1184.1 208.6 33.1 328.7 671.4 583.1 1304.8 18580.2 384.9 735.2 677.7 21.5 1786.8 502.6 192.6 13.6 35.4 484.0 507.9 312.9 189.2 694.7 1861.9 3024.7 800.9 246.0 243.3 244.6 587.1 1310.8 202.4 357.7 467.0 978.1 281.0 186.7 336.4 662.6 GREM1 "CKTSF1B1, CRAC1, DAND2, DRM, gremlin, HMPS" ENSG00000166923 "Gremlin 1, DAN family BMP antagonist" O60565 15 32718004-32745106 "Disease related genes, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 113.0;smooth muscle: 68.2" "Cell type enhanced" "Detected in many" "Collecting duct cells: 66.2;Granulosa cells: 121.1;Oligodendrocytes: 40.5;Skeletal myocytes: 181.4" "Cancer enhanced" "Detected in many" "stomach cancer: 24.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 294.7;BJ hTERT+: 468.5;BJ hTERT+ SV40 Large T+ RasG12V: 286.8;fHDF/TERT166: 957.0;hTEC/SVTERT24-B: 227.8" "Group enriched" "Detected in many" 5 "hippocampal formation: 3.2;olfactory bulb: 10.9" "Low region specificity" "Detected in many" HPA007526 Uncertain "Secreted to blood" NA NA 242000000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "HPA007526: AB_1849971" "unprognostic (4.74e-2)" "unprognostic (2.78e-1)" "unprognostic (4.63e-2)" "unprognostic (6.80e-2)" "unprognostic (3.58e-1)" "unprognostic (1.72e-1)" "unprognostic (3.19e-1)" "prognostic unfavorable (4.46e-4)" "unprognostic (5.33e-2)" "unprognostic (2.32e-1)" "unprognostic (7.20e-3)" "unprognostic (2.79e-1)" "unprognostic (2.13e-11)" "unprognostic (1.77e-2)" "unprognostic (6.60e-2)" "unprognostic (3.29e-2)" "unprognostic (1.16e-3)" 32.7 0.5 1.4 6.5 3.6 0.2 5.5 1.1 2.4 44.7 0.0 36.1 2.6 9.6 0.0 13.6 1.1 113.0 1.3 1.5 1.3 1.2 1.1 2.2 1.1 3.1 3.0 0.3 2.2 0.0 0.2 0.3 1.8 8.2 26.7 0.1 0.6 3.8 0.6 7.6 52.3 68.2 1.1 0.8 36.8 0.5 3.8 0.0 2.3 0.0 1.7 21.7 50.4 6.1 0.0 3.5 0.0 0.0 11.1 12.5 0.0 294.7 468.5 112.5 286.8 0.3 0.0 0.0 0.0 957.0 0.0 0.0 0.0 0.0 109.7 0.0 0.1 0.0 0.1 0.0 3.3 0.0 0.0 3.1 0.0 227.8 0.1 70.6 0.0 0.0 0.0 0.0 143.4 0.1 0.0 0.0 1.2 0.0 0.9 0.0 20.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.2 0.0 0.0 57.7 0.0 0.1 1.1 0.0 0.0 0.0 0.0 2.2 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.4 3.6 1.1 2.4 1.5 1.3 3.1 3.0 1.8 1.1 3.8 6.1 0.7 0.0 0.0 0.3 0.4 6.6 6.5 0.0 0.6 2.1 1.7 0.9 3.4 0.0 0.0 66.2 2.1 0.2 0.7 0.4 0.0 0.4 0.2 0.6 2.3 1.9 0.0 0.0 2.5 0.0 0.1 17.7 0.0 0.7 0.0 121.1 0.7 1.2 1.0 1.7 0.5 0.6 0.0 0.3 12.8 0.0 0.0 2.3 3.6 0.0 2.7 0.3 0.0 1.5 40.5 0.3 0.0 0.4 0.2 9.9 0.1 0.3 0.0 1.3 0.0 181.4 16.1 0.1 1.4 0.3 4.5 0.3 2.1 0.1 0.1 6.5 GRHL2 "BOM, DFNA28, FLJ13782, TFCP2L3" ENSG00000083307 "Grainyhead like transcription factor 2" Q6ISB3 8 101492439-101669726 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Corneal dystrophy, Deafness, Disease variant, Dwarfism, Ectodermal dysplasia, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 28.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 32.1;Respiratory ciliated cells: 28.8;Squamous epithelial cells: 27.1;Suprabasal keratinocytes: 26.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 39.3;CACO-2: 28.0;HaCaT: 46.3;hTCEpi: 35.5;MCF7: 32.7;OE19: 37.9;RT4: 68.9;T-47d: 79.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA004820, HPA062839" Uncertain Supported Nucleoplasm NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA004820: AB_1857928, HPA062839: AB_2684878" "prognostic unfavorable (6.43e-4)" "unprognostic (2.54e-2)" "unprognostic (4.09e-2)" "unprognostic (2.95e-2)" "unprognostic (2.68e-1)" "unprognostic (4.79e-2)" "unprognostic (1.90e-1)" "unprognostic (2.66e-1)" "unprognostic (1.64e-1)" "unprognostic (8.59e-2)" "prognostic unfavorable (6.27e-4)" "unprognostic (2.61e-2)" "unprognostic (8.29e-4)" "unprognostic (4.54e-3)" "unprognostic (2.64e-1)" "unprognostic (1.08e-1)" "unprognostic (1.03e-2)" 0.1 0.0 0.0 1.0 0.0 0.0 12.3 0.0 0.3 6.9 0.0 8.0 4.0 1.7 16.1 20.4 8.5 3.3 0.0 0.0 0.0 6.3 0.4 5.6 0.0 0.0 0.0 0.0 11.1 9.3 0.8 6.7 0.0 23.2 9.2 0.0 14.8 7.2 0.0 28.6 4.3 0.4 0.0 0.1 9.8 0.3 0.0 2.9 10.2 0.0 4.6 7.7 10.4 0.0 39.3 0.0 0.0 0.0 0.0 0.0 19.5 0.0 0.0 0.0 0.0 28.0 18.9 0.0 0.0 0.1 0.0 46.3 0.0 22.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 35.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.7 0.0 0.3 0.2 37.9 0.0 0.0 0.0 0.1 0.0 68.9 1.9 0.0 0.0 15.0 0.0 4.4 79.7 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 32.1 13.0 0.3 0.0 24.3 10.5 7.6 20.5 0.0 14.4 6.1 0.7 17.2 20.8 11.0 0.0 14.0 0.2 10.3 5.9 7.5 2.4 20.0 1.5 0.8 1.2 0.0 0.8 5.5 7.1 0.8 15.3 20.7 0.0 0.0 0.0 0.0 1.4 0.0 1.3 9.8 2.0 0.0 1.1 9.3 0.0 0.3 1.8 0.0 0.6 0.0 0.0 2.0 0.5 8.8 8.5 0.0 1.3 9.3 5.7 0.1 28.8 0.0 0.0 0.5 1.0 0.1 0.0 27.1 26.0 19.8 0.3 0.1 11.0 6.3 GRHL3 "SOM, TFCP2L4" ENSG00000158055 "Grainyhead like transcription factor 3" Q8TE85 1 24319357-24364482 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 120.8;skin 1: 53.5;vagina: 47.7" "Group enriched" "Detected in some" 5 "Squamous epithelial cells: 113.5;Suprabasal keratinocytes: 99.3;Urothelial cells: 78.4" "Group enriched" "Detected in many" 4 "cervical cancer: 13.3;head and neck cancer: 16.1;urothelial cancer: 28.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 46.1;HaCaT: 36.6;MCF7: 58.5;OE19: 21.2;RT4: 64.8;SuSa: 33.3" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA059960 Enhanced Approved Nucleoplasm "Intracellular and membrane" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 28: BEWO - Transcription regulation" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA059960: AB_2684180" "unprognostic (8.99e-2)" "unprognostic (1.23e-1)" "unprognostic (3.95e-2)" "unprognostic (7.83e-3)" "unprognostic (7.58e-3)" "unprognostic (6.28e-3)" "unprognostic (1.20e-1)" "unprognostic (6.34e-2)" "unprognostic (9.01e-3)" "unprognostic (4.03e-2)" "unprognostic (1.24e-1)" "unprognostic (7.36e-2)" "unprognostic (8.59e-4)" "unprognostic (9.79e-2)" "unprognostic (1.83e-1)" "unprognostic (6.97e-3)" "unprognostic (7.42e-2)" 0.2 0.1 0.4 0.3 0.4 0.1 1.9 1.4 0.6 23.3 0.1 0.1 0.6 0.1 1.6 120.8 0.6 0.7 0.0 0.3 1.3 0.2 0.3 0.1 0.0 3.8 4.6 0.0 0.2 0.9 0.2 1.4 3.4 1.5 0.2 0.1 16.7 1.6 0.1 53.5 0.3 0.0 2.3 0.0 0.5 2.3 0.8 1.0 0.0 0.0 25.1 34.7 47.7 1.9 1.2 2.7 1.0 0.0 0.0 0.0 46.1 0.0 0.0 0.3 0.0 0.0 0.5 0.2 0.0 0.0 0.0 36.6 0.1 3.3 0.0 1.2 0.6 0.0 0.3 0.0 0.0 0.0 0.1 0.0 14.2 0.2 2.7 0.0 0.0 0.0 0.2 0.1 0.0 58.5 0.0 0.2 2.4 21.2 0.0 0.0 0.0 0.2 4.6 64.8 0.3 0.0 0.2 6.3 0.0 33.3 4.2 0.4 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.4 1.4 0.6 0.3 1.3 3.8 4.6 3.4 2.3 0.8 1.9 0.0 0.0 0.6 0.0 0.0 14.4 13.2 5.2 8.6 0.0 1.1 0.3 0.5 0.0 6.4 1.8 0.0 4.1 0.0 0.9 0.0 0.4 0.5 3.8 0.1 0.3 0.0 0.0 0.1 0.0 0.8 0.3 0.0 1.3 0.0 0.0 0.0 0.3 0.2 0.0 0.1 0.1 2.0 0.3 2.1 0.3 0.0 0.3 12.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 11.1 0.2 0.0 3.3 0.0 0.0 0.0 0.3 2.6 0.0 113.5 99.3 18.5 0.0 0.0 0.1 78.4 GRID1 "GluD1, KIAA1220" ENSG00000182771 "Glutamate ionotropic receptor delta type subunit 1" Q9ULK0 10 85599552-86366795 "Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 7.4" "Group enriched" "Detected in some" 19 "Astrocytes: 149.8;Excitatory neurons: 284.5;Inhibitory neurons: 301.2;Oligodendrocyte precursor cells: 316.2;Oligodendrocytes: 534.1" "Group enriched" "Detected in many" 5 "glioma: 3.6;thyroid cancer: 6.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 2.4;HEL: 2.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 36: HEL - Hemostasis" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "unprognostic (7.60e-2)" "unprognostic (2.75e-2)" "unprognostic (5.92e-2)" "unprognostic (4.31e-2)" "unprognostic (4.24e-1)" "unprognostic (2.21e-1)" "unprognostic (1.06e-1)" "unprognostic (4.21e-2)" "unprognostic (5.09e-2)" "unprognostic (1.49e-3)" "unprognostic (8.30e-2)" "unprognostic (8.26e-2)" "unprognostic (4.58e-9)" "unprognostic (3.15e-3)" "unprognostic (5.91e-2)" "unprognostic (2.21e-1)" "unprognostic (8.65e-3)" 0.6 0.9 5.3 0.1 5.7 0.0 0.8 3.9 6.9 1.5 0.1 0.3 0.3 1.0 0.7 0.2 1.2 0.2 0.2 5.5 5.4 0.1 0.1 0.4 0.3 5.4 5.4 0.3 0.2 0.2 0.2 0.7 4.8 0.4 0.1 0.7 0.1 0.9 0.2 0.4 0.3 0.4 5.6 0.0 0.4 0.9 5.7 0.1 2.0 0.0 0.2 0.1 0.6 7.4 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 2.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.6 2.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 5.7 3.9 6.9 5.5 5.4 5.4 5.4 4.8 5.6 5.7 7.4 1.1 3.2 0.5 149.8 0.0 0.5 0.1 0.1 2.2 10.5 0.0 0.1 1.0 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.3 1.0 0.0 0.3 0.3 0.0 0.0 284.5 0.2 0.0 2.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 301.2 0.0 0.0 0.0 0.4 3.0 2.1 0.2 5.4 15.9 0.0 0.8 0.0 316.2 534.1 0.0 0.0 4.5 0.0 0.2 0.0 0.0 0.0 0.5 13.1 0.2 5.7 0.1 0.9 0.2 0.0 0.1 0.1 0.0 0.0 0.0 GRIPAP1 "DKFZp434P0630, GRASP-1, GRASP1, KIAA1167, MPMGp800B12492Q3" ENSG00000068400 "GRIP1 associated protein 1" Q4V328 X 48973720-49002264 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 212.7;Rod photoreceptor cells: 169.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000282, HPA000615" Approved Approved Vesicles,Cytosol NA NA "Cluster 6: Non-specific - Transcription" "Cluster 58: Brain - Synaptic function" "Cluster 20: HeLa - Mitochondria" "Cluster 9: Photoreceptor cells - Phototransduction" "Vesicles, Cytosol" "HPA000282: AB_1079022, HPA000615: AB_1079023" "unprognostic (3.34e-1)" "unprognostic (2.86e-3)" "unprognostic (3.24e-3)" "unprognostic (3.93e-3)" "unprognostic (2.68e-1)" "unprognostic (1.23e-1)" "unprognostic (3.97e-3)" "unprognostic (1.01e-2)" "unprognostic (5.26e-2)" "unprognostic (3.65e-1)" "unprognostic (1.69e-3)" "unprognostic (1.06e-2)" "prognostic unfavorable (3.92e-7)" "unprognostic (4.24e-3)" "unprognostic (2.30e-1)" "unprognostic (1.05e-1)" "prognostic favorable (4.63e-7)" 17.2 23.8 30.6 23.6 31.7 35.3 16.6 28.0 35.5 19.6 19.6 19.3 19.0 17.5 24.7 19.3 19.3 13.3 15.3 31.4 30.4 20.6 22.0 21.3 25.4 29.2 29.6 19.9 15.4 22.9 33.6 15.6 29.9 19.0 15.4 48.1 16.7 15.5 18.4 24.4 21.9 14.7 23.1 28.1 19.4 19.7 30.1 26.1 20.9 12.9 24.1 18.0 17.5 32.2 27.9 43.6 30.7 64.3 18.1 13.8 27.7 22.4 27.6 28.3 26.7 23.7 24.0 42.1 12.6 22.3 30.4 39.0 38.5 24.5 22.6 49.3 19.7 34.0 59.8 25.2 31.1 36.7 58.3 14.4 34.5 37.7 27.8 26.2 26.1 35.6 25.2 54.3 26.3 51.5 32.2 49.3 36.3 19.8 23.5 35.3 46.1 33.8 28.0 34.1 27.0 30.0 47.6 18.8 28.4 44.4 42.6 72.5 31.3 14.9 23.2 30.7 18.5 33.0 27.6 29.6 25.9 54.9 25.9 32.5 14.6 21.3 10.1 13.3 8.6 11.3 10.4 9.7 12.0 13.6 8.9 9.5 25.9 15.7 13.0 12.4 9.0 9.5 30.6 31.7 28.0 35.5 31.4 30.4 29.2 29.6 29.9 23.1 30.1 32.2 22.6 9.6 25.1 13.7 28.6 8.2 15.5 25.2 10.8 67.6 11.6 9.1 13.9 22.8 26.7 18.4 212.7 21.2 30.1 25.8 29.4 15.5 9.3 23.8 19.3 21.2 21.7 17.2 32.1 18.4 9.9 14.4 26.0 26.3 43.1 31.2 18.5 18.5 17.2 69.0 32.9 22.4 34.6 27.0 18.7 14.4 17.1 28.5 7.2 10.3 32.7 25.3 33.0 18.1 17.7 18.4 30.6 19.2 22.2 16.9 23.9 19.1 25.5 169.4 19.7 16.9 17.8 11.5 10.1 16.6 14.2 26.1 25.1 35.8 16.5 19.5 GRK3 "ADRBK2, BARK2" ENSG00000100077 "G protein-coupled receptor kinase 3" P35626 22 25564675-25729294 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 30.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 32.2;Club cells: 16.7;Extravillous trophoblasts: 29.2;granulocytes: 18.9;Hofbauer cells: 29.3;Macrophages: 26.4;monocytes: 27.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "classical monocyte: 4.1;eosinophil: 5.2;intermediate monocyte: 7.2;memory B-cell: 4.1;myeloid DC: 3.2;naive B-cell: 5.0;non-classical monocyte: 6.8;plasmacytoid DC: 2.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 43.6;JURKAT: 69.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000804 Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 2: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm "Plasma membrane" "HPA000804: AB_1078281" "unprognostic (1.02e-1)" "unprognostic (4.38e-2)" "unprognostic (5.68e-3)" "unprognostic (4.33e-2)" "unprognostic (2.09e-1)" "unprognostic (3.67e-2)" "unprognostic (3.29e-1)" "unprognostic (1.78e-2)" "unprognostic (1.97e-1)" "unprognostic (3.54e-1)" "unprognostic (1.95e-3)" "unprognostic (5.79e-2)" "unprognostic (1.01e-3)" "unprognostic (1.74e-1)" "unprognostic (2.87e-3)" "unprognostic (1.89e-2)" "prognostic favorable (1.29e-4)" 30.2 5.4 6.5 12.9 8.9 7.8 9.4 2.3 14.7 4.0 0.0 3.1 2.8 5.3 1.3 2.4 8.7 4.7 4.3 18.9 2.6 2.4 3.2 9.4 15.1 5.4 6.2 2.9 7.1 4.2 3.2 4.4 2.5 7.5 3.9 4.8 3.2 1.6 0.9 3.3 4.7 5.9 2.9 18.8 3.8 15.7 7.6 10.2 4.1 1.2 15.6 6.2 1.5 6.0 0.1 3.9 11.9 3.9 8.1 1.0 17.3 1.3 3.8 3.8 6.5 6.4 6.8 22.5 0.3 0.3 10.5 0.2 11.9 9.1 11.1 43.6 7.6 10.3 1.3 14.3 0.3 33.8 16.8 2.0 6.2 2.6 4.6 0.6 0.7 69.4 1.1 0.1 4.4 5.6 24.4 2.4 8.5 12.1 0.0 10.8 18.9 3.8 0.0 6.6 27.6 37.5 2.2 0.1 9.0 10.9 3.3 13.4 0.3 0.1 23.6 0.2 4.9 2.6 9.1 17.4 15.8 11.8 3.7 0.5 4.1 5.2 0.0 7.2 0.2 4.1 0.0 0.2 3.2 5.0 0.1 0.1 0.2 0.0 6.8 2.7 0.3 1.5 6.5 8.9 2.3 14.7 18.9 2.6 5.4 6.2 2.5 2.9 7.6 6.0 3.9 16.0 32.2 0.0 10.2 0.0 0.0 0.0 0.0 0.0 11.7 9.5 0.0 0.0 16.7 0.0 0.0 2.0 1.1 0.0 1.9 9.4 0.0 12.7 5.8 2.4 0.0 0.0 0.0 1.8 29.2 4.1 0.0 2.2 18.9 3.7 0.0 0.0 29.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.4 0.0 0.0 27.4 0.0 0.0 0.0 0.0 3.4 0.0 0.0 2.1 0.0 0.0 1.8 6.6 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 3.3 1.1 5.0 0.0 0.0 GRXCR2 DFNB101 ENSG00000204928 "Glutaredoxin and cysteine rich domain containing 2" A6NFK2 5 145858521-145937126 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Deafness, Non-syndromic deafness" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "Early spermatids: 15.1;Late spermatids: 16.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "cerebral cortex: 1.2;hippocampal formation: 4.1" HPA059421 Uncertain NA NA "Cluster 34: Spermatids - Unknown function" "HPA059421: AB_2684010" "unprognostic (4.71e-2)" "unprognostic (2.91e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 16.8 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GSDME "DFNA5, ICERE-1" ENSG00000105928 "Gasdermin E" O60443 7 24698355-24757940 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" Necrosis "Deafness, Non-syndromic deafness, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 168.1;Distal tubular cells: 41.1;Extravillous trophoblasts: 26.5;Hofbauer cells: 39.9;Syncytiotrophoblasts: 104.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "memory B-cell: 9.0;myeloid DC: 5.9;naive B-cell: 8.4" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011326, CAB019306" Approved Supported Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol "CAB019306: , HPA011326: AB_1847629" "unprognostic (1.08e-1)" "unprognostic (1.77e-2)" "unprognostic (6.29e-2)" "unprognostic (6.36e-3)" "unprognostic (6.70e-2)" "unprognostic (1.49e-2)" "prognostic unfavorable (2.49e-5)" "unprognostic (4.35e-2)" "unprognostic (1.34e-1)" "unprognostic (1.35e-1)" "unprognostic (2.23e-1)" "unprognostic (1.24e-1)" "unprognostic (1.13e-3)" "unprognostic (1.48e-3)" "unprognostic (6.70e-2)" "unprognostic (1.06e-1)" "unprognostic (5.90e-2)" 13.5 7.8 16.4 2.9 16.7 0.5 7.6 13.3 18.0 17.3 9.2 6.4 7.7 24.8 15.3 3.6 14.3 8.5 9.7 18.1 15.0 13.3 4.5 4.4 5.8 19.4 18.7 16.9 2.6 7.3 7.0 35.0 16.1 7.5 2.4 6.3 3.1 21.1 7.8 3.0 26.8 15.1 16.5 1.8 3.9 12.9 14.1 5.8 14.5 5.2 3.8 15.0 10.1 26.6 31.4 21.7 9.6 41.2 51.4 28.6 16.4 24.1 63.6 24.5 34.3 22.9 1.1 0.5 20.6 66.4 81.7 20.5 5.8 105.4 42.8 0.1 2.1 0.8 39.3 48.0 43.0 0.1 1.5 31.3 75.3 43.5 103.1 73.0 42.3 13.8 3.0 5.2 55.3 0.4 1.9 0.8 10.2 0.1 15.7 0.2 33.6 0.0 74.5 21.9 0.4 60.0 36.5 0.6 42.3 24.3 2.2 2.8 27.9 23.1 39.7 31.6 29.2 2.4 0.6 15.5 69.8 0.1 5.8 0.0 1.9 0.0 0.0 0.2 0.0 9.0 0.1 0.0 5.9 8.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.6 16.4 16.7 13.3 18.0 18.1 15.0 19.4 18.7 16.1 16.5 14.1 26.6 1.0 6.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 2.1 3.9 0.0 0.0 0.6 5.5 0.0 168.1 0.0 0.0 41.1 1.9 0.0 0.7 16.9 1.3 0.0 0.0 0.0 0.9 26.5 4.3 0.0 1.0 0.0 4.8 0.0 0.0 39.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 8.3 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 8.8 1.5 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 104.7 0.7 0.9 0.0 0.0 GSG1 MGC3146 ENSG00000111305 "Germ cell associated 1" Q2KHT4 12 13083532-13103683 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "testis: 429.9" "Cell type enriched" "Detected in many" 4 "Late spermatids: 10812.1" "Cancer enhanced" "Detected in single" "testis cancer: 1.9" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 8.8;LHCN-M2: 9.8;RPTEC TERT1: 12.3;U-2 OS: 5.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Intracellular and membrane" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (1.50e-1)" "unprognostic (2.21e-2)" "unprognostic (6.33e-2)" "unprognostic (2.36e-2)" "unprognostic (1.34e-1)" "unprognostic (8.01e-2)" "unprognostic (1.04e-1)" "unprognostic (4.52e-1)" "unprognostic (6.85e-2)" "unprognostic (8.23e-2)" "unprognostic (5.91e-2)" "unprognostic (3.20e-3)" "unprognostic (1.48e-1)" "unprognostic (3.65e-2)" "unprognostic (1.79e-1)" "unprognostic (6.32e-3)" 0.1 0.0 0.6 0.2 0.9 0.8 0.4 1.7 1.4 0.1 1.3 0.1 1.4 0.1 0.6 0.1 0.0 0.2 0.1 0.7 0.5 0.5 0.1 0.1 0.3 0.0 0.0 0.1 4.8 0.0 0.2 0.2 0.0 0.4 0.2 30.4 0.1 0.0 0.3 0.2 0.7 0.0 0.0 0.2 0.1 429.9 0.1 0.1 0.1 0.0 0.1 0.0 0.1 1.4 0.1 0.4 0.3 0.1 2.0 1.2 0.4 0.2 0.4 0.3 0.4 0.2 0.1 0.2 0.1 8.8 0.6 0.1 0.1 0.0 0.8 0.2 0.0 0.2 0.6 0.3 0.0 0.2 0.1 0.8 0.0 1.6 0.1 0.1 0.0 0.1 0.1 1.6 9.8 0.2 0.1 1.0 2.1 0.1 0.2 0.1 3.5 0.1 12.3 0.2 0.6 0.2 0.3 0.0 0.1 0.3 0.0 1.4 0.1 0.5 5.9 0.3 0.3 0.5 0.3 0.1 2.5 0.2 0.1 0.2 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.6 0.9 1.7 1.4 0.7 0.5 0.0 0.0 0.0 0.0 0.1 1.4 0.1 3.2 1.1 0.3 0.0 0.1 0.1 0.0 0.0 134.9 0.1 0.0 0.3 1.5 0.0 0.0 6.2 0.1 0.0 0.0 1.9 0.6 2248.2 0.1 0.2 2.8 27.5 2.7 1.8 0.0 0.1 0.7 0.0 0.1 0.0 0.0 1.4 0.0 0.6 1.7 0.8 2.0 2.0 0.3 0.0 10812.1 53.4 2.9 0.0 1.0 0.1 6.7 0.0 0.0 0.1 0.0 1.2 39.9 0.0 0.1 0.1 0.0 0.0 16.1 6.6 0.4 0.1 57.0 27.1 0.0 0.0 0.0 0.1 0.1 0.1 0.1 GSS ENSG00000100983 "Glutathione synthetase" P48637 20 34928432-34956027 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glutathione biosynthesis" Ligase "Disease variant, FDA approved drug targets, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 164.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054508, HPA059315" Enhanced Supported Nucleoplasm NA NA 28000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "HPA054508: AB_2682509, HPA059315: AB_2683976" "unprognostic (5.80e-2)" "unprognostic (1.50e-1)" "unprognostic (1.14e-1)" "unprognostic (7.21e-2)" "unprognostic (3.63e-2)" "unprognostic (5.68e-2)" "prognostic unfavorable (7.21e-5)" "unprognostic (2.90e-2)" "unprognostic (8.52e-2)" "unprognostic (3.64e-1)" "unprognostic (6.49e-2)" "unprognostic (1.50e-1)" "prognostic favorable (7.31e-6)" "unprognostic (3.35e-3)" "unprognostic (1.96e-1)" "unprognostic (1.42e-3)" "unprognostic (1.52e-1)" 18.8 46.9 24.2 17.7 25.6 27.1 23.8 21.4 26.2 21.1 24.6 41.1 30.4 17.4 67.7 43.4 26.9 17.9 24.8 25.4 25.3 42.7 44.8 21.7 15.9 23.7 25.1 14.3 15.7 27.7 26.4 19.8 25.5 34.2 40.6 15.7 28.9 18.6 20.4 34.6 28.4 19.1 22.9 23.7 28.5 23.7 25.9 21.5 23.2 16.9 18.5 22.9 26.1 25.4 63.7 75.7 36.2 51.2 41.4 42.8 51.5 52.9 48.7 81.6 67.1 139.9 75.5 44.8 68.6 54.9 78.7 58.7 53.6 134.8 68.5 20.9 30.4 176.1 46.8 140.1 58.1 44.8 59.5 45.3 141.8 77.0 128.8 36.3 58.4 59.5 87.1 35.7 100.6 70.1 72.5 63.5 21.4 83.2 96.0 64.8 72.7 106.9 117.7 63.9 71.0 41.3 93.6 86.5 70.9 19.7 106.5 40.5 46.7 93.1 52.5 61.7 46.5 35.7 35.9 49.1 79.4 48.6 56.7 17.5 36.2 8.7 30.4 39.2 27.6 12.8 24.0 31.4 43.6 8.7 27.7 23.7 8.4 29.3 36.6 23.9 32.6 29.0 24.2 25.6 21.4 26.2 25.4 25.3 23.7 25.1 25.5 22.9 25.9 25.4 10.6 19.2 10.5 13.4 9.9 26.3 32.5 72.4 38.7 23.0 32.8 20.8 17.1 27.1 38.1 25.8 10.4 79.4 19.1 58.1 25.4 51.6 55.6 14.8 18.2 16.1 23.4 26.9 12.2 47.2 52.5 19.3 37.2 16.4 17.7 80.1 10.0 27.3 59.9 35.3 13.8 50.6 48.8 17.2 17.3 164.1 10.2 26.8 16.0 5.6 31.0 29.6 19.6 10.1 9.9 39.8 40.1 18.4 19.6 21.4 33.8 121.5 18.1 16.9 26.3 12.0 21.0 14.7 18.9 38.1 24.2 49.0 20.6 52.1 77.7 33.0 GSTA2 GST2 ENSG00000244067 "Glutathione S-transferase alpha 2" P09210 6 52750087-52763475 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "kidney: 696.0;liver: 2058.5" "Cell type enhanced" "Detected in many" "Cholangiocytes: 201.6;Distal tubular cells: 213.2;Exocrine glandular cells: 239.6;Pancreatic endocrine cells: 334.7;Proximal enterocytes: 367.0;Proximal tubular cells: 1186.6;Respiratory ciliated cells: 435.5" "Group enriched" "Detected in many" 16 "liver cancer: 124.6;renal cancer: 48.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "CACO-2: 25.9;Hep G2: 20.0" "HPA004342, HPA048934, HPA053817" Supported Supported Cytosol NA NA "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA004342: AB_1078987, HPA048934: AB_2680563, HPA053817: AB_2630367" "unprognostic (1.14e-1)" "unprognostic (1.20e-1)" "unprognostic (2.72e-2)" "unprognostic (1.15e-1)" "unprognostic (6.43e-3)" "unprognostic (2.41e-1)" "unprognostic (1.30e-1)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.17e-4)" "unprognostic (4.34e-2)" "unprognostic (1.91e-1)" "unprognostic (6.54e-2)" 0.4 4.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.6 149.5 0.0 0.7 0.1 2.5 109.4 0.0 0.0 0.0 696.0 2058.5 4.8 0.1 0.0 0.0 0.2 299.2 0.0 0.0 0.1 0.0 3.8 0.1 0.0 0.5 0.0 0.0 0.0 115.5 0.0 0.0 0.0 11.7 44.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 25.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 1.2 0.0 20.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.2 0.0 1.7 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.2 0.7 0.0 0.0 0.6 0.0 0.0 0.3 0.6 0.5 0.5 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 1.7 0.0 0.2 1.5 0.0 0.0 0.1 0.1 0.0 201.6 31.1 16.5 0.0 0.0 0.0 0.1 213.2 8.1 6.9 0.0 0.0 0.6 0.0 0.0 0.0 239.6 0.2 0.5 7.7 0.0 0.0 37.2 0.7 124.2 0.1 0.0 0.0 13.7 2.0 2.2 0.0 14.6 1.2 5.1 0.0 0.0 5.2 0.0 0.0 0.0 0.1 334.7 18.8 0.4 0.0 3.9 367.0 1186.6 435.5 0.0 0.0 0.0 1.5 1.9 0.7 0.0 0.0 0.0 2.6 10.4 30.1 1.3 GSTK1 GST13 ENSG00000197448 "Glutathione S-transferase kappa 1" Q9Y2Q3 7 143244093-143270854 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 1160.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006311, HPA022904" Supported Supported Peroxisomes NA NA 110000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 39: Non-specific - Basic cellular processes" Peroxisomes "HPA006311: AB_1849786, HPA022904: AB_1849787" "prognostic favorable (4.41e-6)" "unprognostic (2.40e-1)" "unprognostic (6.53e-2)" "unprognostic (4.49e-3)" "unprognostic (2.92e-2)" "unprognostic (1.15e-2)" "unprognostic (1.37e-1)" "unprognostic (2.99e-1)" "unprognostic (1.43e-1)" "unprognostic (3.76e-3)" "unprognostic (1.99e-2)" "unprognostic (7.27e-2)" "prognostic favorable (2.10e-6)" "unprognostic (2.66e-2)" "unprognostic (2.94e-1)" "unprognostic (9.13e-2)" "unprognostic (2.15e-2)" 150.9 180.9 77.5 135.9 82.5 187.0 159.1 82.7 89.2 154.5 141.0 217.9 317.2 95.2 110.7 154.0 144.7 140.6 271.7 75.7 82.7 257.2 449.3 125.1 185.0 85.2 84.0 71.1 138.0 308.2 79.7 104.2 85.3 111.4 230.8 26.9 213.0 96.4 238.6 132.6 277.1 106.6 79.8 236.5 163.4 85.1 83.3 96.2 160.1 324.1 183.7 129.5 112.4 88.6 150.7 106.1 14.7 130.1 224.2 319.7 68.8 87.0 148.4 76.3 150.8 64.5 375.2 85.4 120.8 126.7 114.5 222.4 57.5 136.2 66.0 165.0 62.3 69.6 80.9 102.9 154.1 84.7 108.4 290.4 164.3 88.0 62.0 113.1 205.3 109.5 99.3 100.9 207.2 116.2 87.3 152.9 34.7 291.3 158.6 73.9 2.4 169.6 266.1 81.6 59.7 81.4 159.4 256.3 137.4 88.3 123.6 117.0 122.2 41.0 37.7 108.5 75.2 171.0 86.5 20.0 148.5 336.0 86.6 351.1 537.1 210.7 298.5 597.9 289.7 254.5 554.6 386.4 445.2 183.2 281.3 274.6 165.0 188.3 641.7 187.0 800.5 917.1 77.5 82.5 82.7 89.2 75.7 82.7 85.2 84.0 85.3 79.8 83.3 88.6 181.9 70.5 95.6 17.0 134.1 114.2 174.9 244.0 118.4 11.6 181.9 198.2 172.9 211.6 219.5 121.4 12.5 295.3 151.4 301.6 291.6 160.5 561.3 102.7 95.8 117.0 153.6 63.3 25.8 120.3 132.0 96.4 185.5 92.9 145.1 47.4 155.3 322.1 304.2 8.4 28.8 252.8 154.6 288.3 174.1 1160.2 72.7 195.8 151.2 16.9 228.5 85.9 194.7 16.6 14.3 104.5 505.2 50.8 130.0 82.9 670.0 620.2 154.0 15.4 85.5 65.9 121.7 6.9 10.3 166.3 116.4 183.7 250.7 150.7 366.5 218.9 GSTM3 GST5 ENSG00000134202 "Glutathione S-transferase mu 3" P21266 1 109733932-109741038 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 377.9" "Cell type enhanced" "Detected in all" "Distal tubular cells: 802.2;Early spermatids: 2092.4;Late spermatids: 3843.4;Spermatocytes: 1177.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "eosinophil: 3.4;gdT-cell: 3.1;memory CD4 T-cell: 3.9;memory CD8 T-cell: 2.2;naive CD4 T-cell: 7.8;naive CD8 T-cell: 4.3;T-reg: 1.9" "Group enriched" "Detected in many" 7 "granulocytes: 3.4;T-cells: 7.8" "Cell line enhanced" "Detected in many" "SK-BR-3: 228.4;T-47d: 479.6;WM-115: 186.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB017130, HPA035190, CAB040583, HPA055972" Enhanced Approved Cytosol NA NA 790000 "Cluster 32: T-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "CAB017130: , CAB040583: , HPA035190: AB_10795023, HPA055972: AB_2682992" "unprognostic (2.13e-2)" "unprognostic (2.76e-2)" "unprognostic (1.95e-1)" "unprognostic (5.87e-2)" "unprognostic (1.25e-1)" "unprognostic (7.28e-2)" "unprognostic (3.28e-3)" "unprognostic (1.98e-1)" "prognostic unfavorable (1.89e-4)" "unprognostic (3.45e-1)" "unprognostic (1.51e-1)" "unprognostic (2.30e-1)" "unprognostic (6.16e-3)" "unprognostic (1.38e-2)" "unprognostic (1.21e-2)" "unprognostic (1.90e-2)" "unprognostic (3.48e-2)" 38.7 39.0 56.9 11.0 61.1 3.3 83.5 50.3 69.1 52.7 109.7 45.0 46.8 32.1 243.2 53.6 35.1 47.0 74.8 56.9 63.6 188.1 20.0 23.6 6.2 54.4 54.8 120.4 101.0 41.1 33.7 21.6 55.5 47.5 19.9 21.1 22.6 165.9 65.8 57.2 27.8 58.3 57.5 14.1 76.2 377.9 61.6 13.2 57.9 51.2 7.9 57.1 53.2 58.3 0.2 6.9 49.3 0.1 64.5 39.9 8.5 54.3 9.4 58.2 56.2 21.8 1.9 0.1 30.8 27.8 40.1 2.6 10.0 22.3 80.5 0.3 14.9 50.8 152.1 33.9 69.5 0.0 115.2 40.3 27.0 87.8 0.1 63.5 73.1 61.9 4.7 0.6 26.6 30.0 14.5 1.2 5.3 0.2 93.1 0.4 31.9 2.3 16.3 117.1 86.1 46.0 112.5 228.4 10.5 14.1 479.6 75.3 57.9 0.8 20.9 59.6 36.3 7.7 13.1 0.2 0.6 0.1 186.9 0.3 0.1 3.4 3.1 0.1 0.8 0.3 3.9 2.2 0.1 0.2 7.8 4.3 0.9 0.7 0.1 0.5 1.9 1.5 56.9 61.1 50.3 69.1 56.9 63.6 54.4 54.8 55.5 57.5 61.6 58.3 22.2 6.4 11.5 18.3 7.0 143.5 97.2 104.4 50.1 17.5 196.1 176.8 88.0 50.1 35.9 222.5 6.2 16.3 8.7 17.3 802.2 88.0 2092.4 51.4 40.6 32.9 50.4 33.0 7.5 149.5 9.0 131.6 43.8 93.6 9.5 22.7 58.2 14.2 10.6 15.2 8.0 24.9 28.5 13.9 54.1 3843.4 385.5 15.1 60.5 2.8 3.5 247.5 2.1 14.6 1.7 126.4 32.5 276.1 3.4 53.7 116.9 38.9 5.4 19.2 190.7 23.8 94.4 1177.6 54.4 71.9 107.4 10.3 24.4 121.4 44.1 80.8 GSTO2 ENSG00000065621 "Glutathione S-transferase omega 2" Q9H4Y5 10 104268873-104304950 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Oxidoreductase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 35.9" "Cell type enhanced" "Detected in many" "Distal tubular cells: 133.1;Early spermatids: 314.6;Late spermatids: 442.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ hTERT+: 16.9;CAPAN-2: 17.1;hTCEpi: 16.2;hTERT-HME1: 18.3;OE19: 22.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA048141 Approved NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 34: Spermatids - Unknown function" "HPA048141: AB_2680281" "unprognostic (5.77e-2)" "unprognostic (6.69e-2)" "unprognostic (7.15e-2)" "unprognostic (1.80e-1)" "unprognostic (2.48e-1)" "unprognostic (3.11e-2)" "unprognostic (3.12e-1)" "unprognostic (2.15e-1)" "unprognostic (7.42e-2)" "unprognostic (5.28e-2)" "unprognostic (1.44e-1)" "unprognostic (1.02e-1)" "prognostic favorable (7.10e-7)" "unprognostic (4.56e-2)" "unprognostic (3.92e-2)" "unprognostic (1.75e-2)" "unprognostic (3.47e-1)" 0.5 3.5 5.0 0.3 5.7 2.0 5.2 3.4 5.3 4.3 0.4 4.4 2.8 2.2 4.9 11.8 4.3 1.2 0.6 4.4 4.1 14.0 2.8 2.4 0.3 2.2 2.5 5.4 16.7 5.0 14.6 1.0 2.6 8.3 3.1 6.0 7.5 3.2 1.4 14.8 3.5 1.2 1.1 0.5 10.9 35.9 4.3 2.2 7.0 1.3 0.7 3.8 7.5 5.3 10.2 1.4 0.5 0.6 0.6 1.3 1.4 9.6 16.9 4.7 4.9 0.6 17.1 1.6 4.0 0.8 0.5 10.7 0.5 5.3 1.2 1.1 3.2 0.5 3.1 2.4 2.1 0.7 0.7 1.7 16.2 0.3 18.3 1.3 0.8 1.7 1.5 2.9 1.3 12.3 0.1 0.5 1.7 22.1 1.1 0.5 0.7 0.3 4.6 6.5 0.6 1.1 3.3 2.4 2.9 0.8 12.6 0.3 2.4 1.5 5.1 0.6 0.5 2.8 6.4 0.4 1.5 0.8 0.5 0.2 0.1 0.7 0.5 0.2 0.3 0.3 0.5 0.3 0.0 0.5 0.7 0.4 1.7 1.0 0.1 0.3 1.2 0.2 5.0 5.7 3.4 5.3 4.4 4.1 2.2 2.5 2.6 1.1 4.3 5.3 3.6 3.2 21.0 13.1 1.3 34.2 62.1 94.5 50.1 19.0 61.7 78.2 3.0 21.5 46.4 40.5 16.7 14.4 3.8 12.8 133.1 30.6 314.6 26.9 7.6 5.4 54.2 3.6 33.9 63.3 9.9 4.7 31.6 37.6 2.5 3.3 15.7 3.6 1.8 0.0 28.7 34.0 50.8 1.6 3.7 442.8 2.8 2.7 17.8 1.9 2.1 11.1 1.0 24.1 20.1 31.6 29.1 9.8 0.9 25.6 27.1 43.8 31.2 23.0 6.6 3.1 7.4 22.0 8.9 46.0 47.3 6.7 4.3 11.6 40.7 58.0 GTF2A1L ALF ENSG00000242441 "General transcription factor IIA subunit 1 like" Q9UNN4 2 48617798-48733148 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "testis: 60.0" "Cell type enhanced" "Detected in some" "Early spermatids: 9.2;Late spermatids: 2.3;Spermatocytes: 5.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 1.6;hTERT-RPE1: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (3.59e-1)" "unprognostic (7.00e-2)" "unprognostic (2.63e-1)" "unprognostic (4.77e-1)" "unprognostic (5.02e-2)" 2.1 0.5 0.5 0.0 0.5 0.0 1.2 1.4 0.8 2.9 0.7 8.7 0.4 4.2 0.4 0.7 2.9 1.1 0.8 0.4 0.6 1.1 0.2 1.1 0.2 3.4 1.0 2.1 0.2 0.0 0.5 0.2 2.6 2.1 0.1 0.1 0.2 0.2 0.6 0.4 1.7 0.6 2.0 1.3 2.6 60.0 0.8 0.1 0.5 0.1 0.0 4.2 1.6 2.2 0.0 0.2 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.2 0.1 0.0 0.0 1.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.2 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 1.4 0.8 0.4 0.6 3.4 1.0 2.6 2.0 0.8 2.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 GTF2A2 "HsT18745, TFIIA" ENSG00000140307 "General transcription factor IIA subunit 2" P52657 15 59638062-59657541 "Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 1134.9;Late spermatids: 732.8;Spermatocytes: 1264.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056239 Supported Nucleoplasm NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 16: U-266 - Nucleosome" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "HPA056239: AB_2683074" "unprognostic (2.18e-2)" "unprognostic (3.21e-1)" "unprognostic (9.37e-2)" "unprognostic (1.09e-2)" "unprognostic (1.16e-1)" "unprognostic (1.53e-2)" "unprognostic (3.06e-2)" "unprognostic (1.31e-2)" "unprognostic (7.35e-2)" "unprognostic (6.29e-2)" "unprognostic (3.47e-1)" "unprognostic (7.13e-2)" "unprognostic (1.58e-1)" "unprognostic (2.79e-1)" "unprognostic (2.74e-2)" "unprognostic (1.47e-1)" "unprognostic (8.90e-2)" 54.4 56.9 37.6 54.5 39.5 72.0 49.6 42.7 44.0 52.5 38.8 62.8 40.3 48.7 54.6 60.9 46.2 43.6 64.0 38.1 42.7 69.8 49.8 39.7 52.6 41.5 40.1 52.0 43.1 65.4 58.3 43.3 41.0 46.0 51.1 41.9 58.2 34.3 75.1 39.5 42.0 45.4 42.2 43.3 46.3 211.9 38.6 60.0 41.1 55.1 51.8 61.4 65.5 44.1 149.1 206.4 136.8 130.9 83.8 70.5 157.7 164.0 79.8 134.6 133.3 224.4 58.9 136.5 149.5 107.9 197.6 124.3 138.7 100.6 95.4 242.2 112.9 157.4 146.5 143.4 107.5 171.5 134.1 66.0 95.1 112.3 94.9 95.3 87.6 105.6 226.7 136.1 113.6 103.8 112.9 130.8 181.7 49.6 120.0 104.4 142.9 166.5 133.7 172.2 148.0 157.1 152.1 171.5 160.1 180.5 120.7 179.2 121.5 126.4 224.7 142.5 297.7 134.1 426.3 303.8 143.2 284.0 157.2 174.0 129.8 170.3 88.1 140.7 92.4 126.9 103.1 98.9 174.2 100.2 87.4 96.7 70.0 117.5 135.1 201.0 132.7 134.9 37.6 39.5 42.7 44.0 38.1 42.7 41.5 40.1 41.0 42.2 38.6 44.1 109.4 41.7 58.5 17.0 89.8 98.7 184.6 213.0 83.1 51.1 107.3 155.8 120.4 62.9 132.2 64.4 47.9 217.8 99.9 122.4 211.3 148.8 1134.9 129.9 85.8 96.6 82.1 121.4 22.4 148.8 199.7 103.7 51.5 92.4 82.2 87.9 74.6 78.4 148.3 50.5 27.5 100.8 195.3 100.1 107.7 732.8 125.9 101.9 80.0 16.9 158.9 173.8 107.1 24.1 35.4 181.6 104.6 137.3 109.6 210.7 83.5 149.2 129.7 62.2 65.7 102.9 133.7 1264.3 166.3 89.8 106.8 151.9 87.3 120.8 120.5 236.2 GTF2F1 "BTF4, RAP74, TF2F1, TFIIF" ENSG00000125651 "General transcription factor IIF subunit 1" P35269 19 6379572-6393981 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 228.3;Late spermatids: 391.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022793, HPA028707, HPA070752" Supported Enhanced "Nucleoplasm,Vesicles,Cell Junctions" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 16: U-266 - Nucleosome" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "Vesicles, Cell Junctions" "HPA022793: AB_1857946, HPA028707: AB_2672745, HPA070752: AB_2732163" "unprognostic (1.30e-2)" "unprognostic (6.05e-3)" "unprognostic (2.00e-1)" "prognostic favorable (8.39e-4)" "unprognostic (3.18e-1)" "unprognostic (8.46e-2)" "unprognostic (1.05e-1)" "unprognostic (1.38e-1)" "unprognostic (1.23e-1)" "unprognostic (5.99e-2)" "unprognostic (6.45e-3)" "unprognostic (6.96e-2)" "prognostic favorable (9.80e-4)" "unprognostic (1.34e-2)" "unprognostic (7.02e-2)" "unprognostic (9.92e-2)" "unprognostic (4.25e-1)" 35.0 38.1 36.7 34.0 38.4 71.0 34.2 43.6 43.0 48.8 30.2 41.2 40.5 48.5 25.9 46.0 44.8 36.1 32.8 39.1 35.8 37.6 30.0 31.5 43.5 34.4 34.3 73.6 57.5 42.6 49.8 26.8 34.6 39.5 23.3 24.9 43.8 31.7 36.8 36.8 39.2 25.1 30.1 36.4 43.9 68.3 36.1 37.1 49.6 22.6 29.8 37.3 41.0 36.1 115.6 97.1 62.0 100.9 46.5 73.1 47.3 81.7 84.7 112.0 106.0 104.4 48.5 76.3 111.9 67.2 73.5 109.9 69.3 65.6 57.1 106.6 90.1 97.2 60.7 86.9 78.6 107.1 79.5 82.8 78.2 85.5 64.1 86.4 69.0 72.9 115.9 91.7 63.9 96.2 115.4 79.7 108.2 59.7 124.3 101.5 68.0 94.6 67.5 74.2 76.1 99.8 83.0 64.5 95.6 36.4 84.0 94.0 79.8 78.5 62.6 134.0 110.1 153.9 197.2 79.7 98.1 124.9 91.0 10.2 29.7 20.8 26.1 28.4 29.7 32.9 23.5 24.9 23.3 31.6 27.0 24.6 40.1 27.6 30.2 30.3 25.4 19.8 36.7 38.4 43.6 43.0 39.1 35.8 34.4 34.3 34.6 30.1 36.1 36.1 29.2 48.1 56.6 5.2 51.9 24.3 50.2 40.5 53.5 27.6 43.1 34.7 28.9 32.9 58.4 25.8 8.4 46.1 51.6 88.2 21.5 48.5 228.3 70.5 70.7 41.0 30.5 51.7 6.9 50.8 43.0 43.3 51.0 57.4 63.8 32.7 58.9 26.0 60.2 25.2 7.0 53.4 24.4 54.8 25.9 391.6 44.4 42.1 33.8 5.6 66.0 35.6 49.4 3.5 4.9 47.4 66.0 49.7 55.4 29.9 65.3 48.8 83.6 33.5 32.9 44.8 52.9 71.8 38.3 44.9 21.0 54.0 48.3 41.8 54.4 40.6 GTF2H5 "bA120J8.2, C6orf175, FLJ30544, TFB5, TFIIH, TTD, TTD-A, TTDA" ENSG00000272047 "General transcription factor IIH subunit 5" Q6ZYL4 6 158168350-158199344 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 425.8;Proximal tubular cells: 504.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 39: Non-specific - Basic cellular processes" "unprognostic (1.04e-2)" "unprognostic (2.02e-2)" "unprognostic (2.50e-1)" "unprognostic (8.59e-3)" "unprognostic (3.56e-1)" "unprognostic (1.03e-2)" "unprognostic (1.06e-1)" "unprognostic (2.15e-1)" "unprognostic (1.36e-1)" "unprognostic (2.56e-1)" "unprognostic (1.02e-1)" "unprognostic (5.22e-3)" "prognostic unfavorable (6.11e-4)" "unprognostic (3.13e-1)" "unprognostic (8.46e-2)" "unprognostic (3.58e-3)" "unprognostic (1.33e-2)" 18.0 21.5 18.9 8.3 20.7 5.1 14.1 19.0 32.5 9.1 17.9 9.6 7.4 8.0 20.8 10.1 10.7 7.8 14.0 19.7 20.1 17.7 21.8 7.7 9.9 19.3 18.7 10.2 11.3 13.5 3.2 8.3 19.6 12.7 7.8 18.2 9.0 10.8 27.7 7.2 8.2 9.6 19.7 9.2 8.9 15.1 19.3 15.4 8.4 18.1 9.8 11.3 3.1 21.3 18.5 14.6 24.3 27.5 32.2 40.7 20.8 30.2 26.4 24.7 30.4 10.2 17.4 20.6 48.5 29.6 42.7 13.7 12.0 29.4 29.3 26.6 33.3 28.1 16.1 44.2 29.4 16.1 14.4 36.2 30.2 23.8 29.0 48.5 19.9 29.3 34.3 14.7 46.7 11.1 24.7 39.1 25.2 23.2 17.3 15.6 15.1 32.4 50.3 16.2 18.4 14.7 26.9 26.1 27.0 31.0 21.6 38.1 31.8 18.4 22.5 25.5 39.4 14.1 16.9 30.0 37.1 15.3 38.0 11.6 23.8 16.9 25.4 31.1 22.4 32.7 27.9 25.9 30.6 27.8 33.0 31.7 5.6 31.9 33.4 41.9 35.9 24.3 18.9 20.7 19.0 32.5 19.7 20.1 19.3 18.7 19.6 19.7 19.3 21.3 79.5 44.8 58.4 16.6 49.6 45.5 113.4 232.9 46.1 45.7 91.3 122.2 86.8 88.6 130.4 141.6 16.7 187.8 62.9 44.6 418.7 130.1 425.8 207.5 76.0 61.8 46.6 33.7 15.6 122.4 167.4 93.0 54.0 120.6 65.2 126.7 92.4 180.4 162.0 47.1 18.7 75.1 166.8 80.0 49.2 103.3 112.5 80.3 80.0 11.2 120.6 120.5 117.4 14.1 25.9 92.1 52.7 110.2 24.6 94.3 71.2 504.1 205.0 50.2 72.3 71.8 87.7 227.3 130.6 98.4 63.1 132.8 57.8 177.5 76.1 127.2 GTF2IRD1 "BEN, Cream1, GTF3, MusTRD1, RBAP2, WBSCR11, WBSCR12" ENSG00000006704 "GTF2I repeat domain containing 1" Q9UHL9 7 74453790-74602605 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 68.1" "Cell type enhanced" "Detected in many" "Astrocytes: 48.3;Inhibitory neurons: 42.1;Rod photoreceptor cells: 41.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044254 Approved Supported Nucleoplasm,Cytosol Yes No "Cluster 13: Striated muscle - Muscle contraction" "Cluster 30: Epithelial cell lines - Translation" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm Cytosol "HPA044254: AB_10964747" "unprognostic (8.92e-2)" "unprognostic (6.94e-2)" "unprognostic (1.61e-1)" "prognostic unfavorable (9.71e-5)" "unprognostic (2.24e-1)" "unprognostic (3.35e-2)" "unprognostic (2.71e-3)" "unprognostic (3.77e-2)" "unprognostic (1.84e-2)" "unprognostic (6.26e-2)" "unprognostic (4.89e-3)" "unprognostic (3.31e-1)" "unprognostic (2.53e-1)" "unprognostic (8.61e-2)" "unprognostic (1.08e-1)" "unprognostic (3.06e-2)" "unprognostic (2.25e-3)" 6.0 12.6 7.0 3.4 7.0 0.5 6.9 7.2 8.1 16.8 14.0 15.1 7.7 11.3 8.6 26.7 8.8 5.7 11.6 6.0 8.4 18.6 4.6 11.7 1.0 9.2 8.9 10.5 10.0 18.9 27.6 5.8 9.0 13.3 5.6 36.7 17.3 8.2 68.1 22.4 6.7 8.4 6.7 2.0 13.9 5.0 10.1 3.4 17.4 29.7 5.4 15.0 19.8 10.2 21.2 12.9 28.1 30.8 22.2 10.8 0.2 8.8 23.7 17.1 17.7 21.7 30.1 5.4 6.5 18.1 41.7 11.6 22.6 10.2 12.6 0.2 13.0 1.1 43.1 26.1 71.2 0.2 0.7 14.7 42.1 12.0 48.9 39.7 8.9 10.4 15.5 0.1 19.2 26.1 2.7 18.9 22.6 25.7 12.8 28.1 16.4 20.0 32.7 14.6 23.1 30.5 21.7 39.0 19.9 14.2 23.4 21.2 4.6 17.5 16.9 11.4 20.5 1.1 3.4 8.9 6.7 0.3 14.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 7.0 7.0 7.2 8.1 6.0 8.4 9.2 8.9 9.0 6.7 10.1 10.2 0.9 9.6 8.2 48.3 0.1 7.9 9.9 10.5 9.6 30.8 5.6 4.1 10.4 12.8 6.8 9.2 33.3 1.4 1.5 4.5 11.7 7.6 1.6 11.5 8.0 4.1 4.2 0.8 24.6 9.2 1.8 5.6 6.1 17.0 2.5 8.0 2.9 3.1 2.6 21.9 42.1 3.6 8.2 1.2 5.7 0.3 4.1 2.5 7.2 14.0 0.7 5.9 1.0 25.6 24.9 11.6 3.2 5.7 0.0 17.8 3.6 17.4 12.7 41.1 0.0 19.0 5.7 0.1 3.7 18.2 6.7 2.9 1.1 2.4 7.4 15.8 GTF3C6 "bA397G5.3, C6orf51, TFIIIC35" ENSG00000155115 "General transcription factor IIIC subunit 6" Q969F1 6 110958706-110967890 "Predicted intracellular proteins" Transcription DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056179, HPA061345" Approved Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "Nuclear bodies" "HPA056179: AB_2683058, HPA061345: AB_2684485" "unprognostic (6.98e-2)" "unprognostic (1.38e-1)" "unprognostic (2.66e-1)" "unprognostic (3.04e-1)" "unprognostic (6.99e-2)" "unprognostic (2.34e-1)" "prognostic unfavorable (7.27e-6)" "unprognostic (2.08e-2)" "unprognostic (9.79e-3)" "unprognostic (2.89e-1)" "unprognostic (5.42e-2)" "unprognostic (7.75e-2)" "unprognostic (1.42e-3)" "unprognostic (9.31e-2)" "unprognostic (1.69e-1)" "unprognostic (2.39e-2)" "unprognostic (1.14e-2)" 53.2 55.0 71.5 53.5 73.6 53.5 47.1 73.7 114.9 42.0 73.4 66.9 52.3 30.8 45.8 44.8 45.2 57.8 86.6 70.8 76.3 76.2 51.3 33.9 55.8 72.4 72.6 28.2 30.8 65.3 37.1 32.5 72.7 94.6 65.4 39.0 38.3 41.6 231.2 31.1 46.7 48.7 72.9 33.6 49.8 61.9 72.3 49.7 40.2 168.0 58.1 61.1 27.5 74.9 85.8 154.0 166.5 155.7 59.9 121.9 145.4 143.8 105.1 131.9 109.2 229.0 74.7 121.1 137.8 132.9 30.4 38.6 141.1 120.0 145.5 175.9 205.3 234.2 145.9 347.5 113.4 360.9 190.8 121.4 103.3 115.2 112.8 89.7 155.2 154.3 281.7 79.4 246.8 166.5 198.6 371.4 169.9 109.6 121.0 183.2 95.6 109.7 221.5 214.7 105.4 148.5 107.0 16.8 133.0 98.6 58.7 244.2 163.0 38.2 112.0 260.5 232.3 51.7 127.2 235.9 39.7 208.1 191.3 112.6 116.9 71.0 104.2 170.7 117.9 164.1 130.0 131.0 158.3 133.7 100.9 118.9 18.5 116.2 141.1 173.4 292.4 167.5 71.5 73.6 73.7 114.9 70.8 76.3 72.4 72.6 72.7 72.9 72.3 74.9 58.0 70.5 47.1 12.7 67.1 30.3 70.9 169.2 34.1 37.6 85.3 90.4 279.1 203.0 99.5 104.8 16.7 94.6 75.0 138.8 305.2 190.4 169.1 119.1 82.0 66.0 109.8 86.9 4.9 293.0 251.1 66.4 47.9 167.8 54.4 71.2 55.6 94.5 284.6 26.9 6.7 98.6 144.5 79.8 50.1 223.9 65.0 104.5 55.2 6.5 172.4 133.2 81.4 7.1 13.4 210.8 125.2 68.4 78.3 126.9 118.9 404.7 74.9 37.0 65.7 63.5 88.1 153.1 105.8 72.5 29.7 90.4 72.3 120.2 121.4 117.8 GTSF1L "C20orf65, dJ1028D15.4, FAM112A" ENSG00000124196 "Gametocyte specific factor 1 like" Q9H1H1 20 43726164-43727002 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 147 "testis: 223.7" "Group enriched" "Detected in some" 115 "Early spermatids: 2791.6;Late spermatids: 4158.1" "Cancer enriched" "Detected in single" 5 "testis cancer: 0.5" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 5 "T-reg: 4.0" "Lineage enriched" "Detected in single" 5 "T-cells: 4.0" "Cell line enhanced" "Detected in some" "REH: 1.1;U-698: 1.2" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA054694 Enhanced Uncertain Nucleoli NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 36: Testis - Spermatogenesis" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 31: Spermatids - Spermatogenesis" Nucleoli "HPA054694: AB_2682576" "unprognostic (2.61e-2)" "unprognostic (4.24e-6)" "unprognostic (9.96e-3)" "unprognostic (1.30e-4)" "unprognostic (3.50e-2)" "unprognostic (6.70e-2)" "unprognostic (2.15e-2)" "unprognostic (3.06e-2)" "unprognostic (2.45e-7)" "unprognostic (1.19e-1)" "unprognostic (9.54e-2)" "unprognostic (6.07e-3)" 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.7 0.0 223.7 0.0 0.4 0.1 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.3 0.5 0.0 0.6 0.3 0.3 0.0 0.0 0.0 0.0 4.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2791.6 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4158.1 19.6 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.1 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 30.2 10.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GUCA1A "C6orf131, COD3, CORD14, dJ139D8.6, GCAP, GCAP1, GUCA, GUCA1" ENSG00000048545 "Guanylate cyclase activator 1A" P43080 6 42155406-42181338 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Cone-rod dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 91 "retina: 804.8" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 667.2;Late spermatids: 432.4;Muller glia cells: 219.9;Rod photoreceptor cells: 1191.6" "Cancer enriched" "Detected in single" 9 "testis cancer: 3.5" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 10 "plasmacytoid DC: 4.9" "Lineage enriched" "Detected in single" 10 "dendritic cells: 4.9" "Group enriched" "Detected in some" 8 "NTERA-2: 3.8;SH-SY5Y: 4.5" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA005561, HPA075056" Enhanced Approved "Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 79: Retina - Phototransduction" "Cluster 5: NTERA-2 - Transcription" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane" "HPA005561: AB_2667361, HPA075056: " "unprognostic (1.91e-2)" "unprognostic (3.92e-3)" "unprognostic (2.49e-2)" "unprognostic (9.16e-2)" "unprognostic (1.04e-4)" "unprognostic (9.70e-2)" "unprognostic (6.71e-3)" "unprognostic (1.89e-1)" "unprognostic (1.59e-2)" "unprognostic (3.08e-3)" "unprognostic (2.79e-1)" "unprognostic (1.51e-1)" "unprognostic (1.54e-1)" "unprognostic (1.16e-1)" 0.0 0.0 1.5 0.1 3.5 0.1 0.0 0.9 1.8 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 5.4 0.0 0.0 0.0 0.1 1.5 1.4 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 804.8 0.0 0.0 0.1 0.1 0.1 0.1 0.8 0.0 0.0 8.8 6.2 0.0 0.0 0.0 0.2 0.0 0.1 1.2 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.5 0.0 0.0 4.9 0.0 0.0 1.5 3.5 0.9 1.8 1.3 5.4 1.5 1.4 1.4 0.8 6.2 1.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 140.7 0.0 0.0 0.3 0.0 0.0 0.0 667.2 0.6 1.3 0.0 0.0 0.0 106.5 0.0 0.0 8.2 0.0 0.0 0.3 0.0 0.3 0.9 0.0 0.0 0.0 0.5 0.0 0.0 0.2 65.6 1.0 0.0 4.1 0.0 0.0 432.4 1.8 0.1 0.0 0.0 5.2 219.9 0.0 0.0 0.1 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.1 1191.6 0.0 0.0 1.2 3.2 3.9 0.0 0.0 0.3 0.0 0.1 0.0 0.1 GUCY2D "CORD6, CYGD, GUC1A4, GUC2D, LCA, LCA1, retGC, RETGC-1, ROS-GC1" ENSG00000132518 "Guanylate cyclase 2D, retinal" Q02846 17 8002615-8020342 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "cGMP biosynthesis, Sensory transduction, Vision" Lyase "Cone-rod dystrophy, Congenital stationary night blindness, Disease variant, Leber congenital amaurosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 24 "retina: 34.2" "Group enriched" "Detected in some" 4 "Cone photoreceptor cells: 62.6;Rod photoreceptor cells: 58.3" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 31 "plasmacytoid DC: 8.0" "Lineage enriched" "Detected in single" 50 "dendritic cells: 8.0" "Cell line enriched" "Detected in some" 5 "JURKAT: 5.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 79: Retina - Phototransduction" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 9: Photoreceptor cells - Phototransduction" "unprognostic (3.57e-4)" "unprognostic (5.05e-1)" "unprognostic (1.49e-1)" "unprognostic (9.75e-5)" "unprognostic (5.94e-2)" "unprognostic (1.86e-1)" "unprognostic (4.44e-2)" "unprognostic (3.81e-2)" "unprognostic (2.92e-1)" "unprognostic (2.26e-1)" "unprognostic (7.54e-2)" "unprognostic (4.44e-1)" "unprognostic (7.59e-5)" "unprognostic (1.05e-1)" "unprognostic (3.46e-1)" "unprognostic (3.08e-1)" "unprognostic (1.07e-1)" 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 34.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.4 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.4 1.3 5.2 5.7 2.1 1.4 3.8 1.9 0.0 1.4 0.0 62.6 1.2 2.7 0.0 1.9 0.1 6.9 0.2 0.1 0.1 0.0 0.0 0.5 0.0 0.7 0.1 0.0 0.6 0.0 0.1 0.0 1.2 1.1 0.0 0.4 0.0 0.0 0.6 0.0 14.9 0.0 0.6 0.0 0.0 0.8 6.1 0.0 0.0 0.1 0.1 0.0 0.4 0.0 1.1 0.0 0.4 0.1 58.3 0.0 0.0 0.0 0.4 0.1 2.4 0.3 2.2 0.1 0.0 0.2 0.5 GUSB ENSG00000169919 "Glucuronidase beta" P08236 7 65960684-65982215 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Cancer-related genes, Disease variant, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 213.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036322, HPA036323" Approved Supported Vesicles "Intracellular and membrane" NA NA 330000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA036322: AB_10670796, HPA036323: AB_2675059" "unprognostic (1.54e-2)" "unprognostic (6.49e-2)" "unprognostic (1.18e-2)" "unprognostic (3.50e-1)" "unprognostic (2.58e-2)" "unprognostic (4.46e-2)" "unprognostic (2.89e-1)" "unprognostic (1.56e-3)" "unprognostic (1.32e-1)" "unprognostic (2.32e-1)" "unprognostic (7.00e-3)" "unprognostic (1.91e-1)" "unprognostic (3.34e-2)" "unprognostic (8.83e-3)" "unprognostic (1.98e-1)" "unprognostic (5.06e-1)" "unprognostic (1.45e-1)" 28.4 18.2 11.0 22.3 12.3 84.2 80.9 12.0 16.1 26.7 14.3 38.2 36.1 26.2 41.8 16.4 24.6 27.6 19.6 10.7 11.5 25.1 104.0 35.7 25.6 13.2 12.2 19.9 33.6 30.3 12.6 48.2 13.2 20.2 41.9 9.7 32.9 21.2 10.9 18.8 29.8 19.1 11.9 34.0 38.1 19.5 13.0 22.7 27.7 14.4 24.0 27.3 15.4 13.5 67.0 26.5 25.2 56.3 80.9 49.1 35.3 21.3 56.8 45.0 42.1 37.0 67.8 30.9 32.3 26.8 24.1 27.5 16.5 25.1 26.8 27.3 34.1 41.5 40.9 27.3 39.7 89.6 67.1 33.4 26.7 26.3 33.3 54.5 39.3 18.0 63.2 213.5 30.5 50.3 34.2 92.0 17.9 103.0 21.0 34.4 55.9 172.4 29.4 42.8 36.2 32.7 55.6 129.1 72.3 29.9 71.1 88.8 28.5 55.3 49.3 21.8 53.6 119.6 151.9 50.0 41.0 116.3 68.3 26.0 80.1 65.7 32.0 103.0 28.4 27.7 24.7 28.4 80.5 22.6 16.8 19.5 13.2 46.6 93.5 34.2 34.5 51.4 11.0 12.3 12.0 16.1 10.7 11.5 13.2 12.2 13.2 11.9 13.0 13.5 53.1 51.3 58.7 10.1 33.0 18.0 32.0 51.9 29.0 12.2 26.1 19.9 12.2 48.6 48.9 29.5 8.4 81.9 32.6 52.2 5.9 41.1 59.1 28.9 26.5 39.7 43.0 47.1 12.3 30.3 61.2 49.5 49.5 49.4 36.8 38.3 37.9 72.7 126.4 16.8 10.6 51.6 30.5 88.1 33.2 46.7 43.2 78.0 39.2 14.0 44.8 28.0 20.6 8.5 14.2 29.4 49.5 28.6 87.5 25.3 50.6 26.8 43.2 20.1 26.3 27.1 26.0 49.6 31.0 16.0 14.8 66.9 32.2 24.4 44.3 29.6 GVQW3 ENSG00000179240 "GVQW motif containing 3" Q3ZCU0 11 76381303-76414619 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "retina: 14.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 3.9;Distal tubular cells: 9.8;granulocytes: 3.8;Granulosa cells: 7.0;Proximal tubular cells: 6.7;Theca cells: 5.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA057405 Uncertain Approved "Nucleoplasm,Endoplasmic reticulum,Centrosome" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Centrosome" "Endoplasmic reticulum" "HPA057405: AB_2683429" "unprognostic (8.90e-2)" "unprognostic (1.16e-1)" "unprognostic (8.27e-2)" "unprognostic (1.92e-1)" "unprognostic (9.04e-3)" "unprognostic (8.56e-2)" "unprognostic (8.87e-2)" "unprognostic (2.91e-2)" "unprognostic (7.28e-3)" "unprognostic (2.21e-1)" "unprognostic (1.04e-2)" "unprognostic (1.49e-1)" "unprognostic (4.05e-4)" "unprognostic (7.45e-2)" "unprognostic (1.09e-1)" "unprognostic (9.28e-2)" "unprognostic (2.13e-1)" 1.1 1.5 1.5 1.4 1.6 1.1 1.9 3.2 2.1 1.7 4.4 1.3 1.4 1.8 1.9 0.4 2.0 0.7 1.0 1.4 0.8 1.4 0.7 0.9 1.9 0.5 0.1 2.2 6.5 1.0 2.4 0.8 0.6 1.2 1.5 14.2 1.9 0.8 1.1 1.4 1.3 0.9 0.0 1.7 1.4 3.4 1.2 2.4 1.9 0.6 1.6 0.9 1.3 1.5 1.1 1.2 4.4 3.2 1.2 1.6 1.5 0.6 0.5 1.1 1.1 3.0 2.0 3.6 1.2 0.5 1.3 2.6 1.9 0.8 1.9 2.0 1.2 1.9 5.0 1.3 0.7 2.5 1.2 0.7 1.2 1.4 0.8 1.0 0.9 4.9 1.2 2.3 0.4 1.3 2.4 3.8 0.9 0.9 1.4 3.7 2.9 1.9 0.7 0.8 6.5 2.9 1.2 0.7 0.7 1.7 2.1 0.8 0.6 2.1 2.2 3.2 0.7 2.1 1.6 4.6 0.8 1.7 1.1 1.5 0.3 0.4 0.4 0.2 0.3 0.5 0.6 0.5 0.2 0.6 0.6 0.6 1.0 0.8 0.2 0.3 0.8 0.2 1.5 1.6 3.2 2.1 1.4 0.8 0.5 0.1 0.6 0.0 1.2 1.5 2.1 0.0 3.9 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.8 2.3 0.0 0.0 2.5 1.8 0.0 1.1 1.7 0.0 9.8 1.2 0.0 2.4 2.5 0.8 0.0 0.0 0.0 0.6 0.6 1.4 0.0 0.6 3.8 7.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 6.7 2.2 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.7 0.9 5.5 0.0 0.0 H2AL1RP ENSG00000229674 "H2A.L variant histone R, pseudogene" X 37994252-37994918 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "brain: 1.2;testis: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA 0.0 0.1 0.6 0.0 1.2 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.7 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 2.4 1.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.2 0.0 0.6 0.6 0.7 0.3 0.2 0.2 0.1 1.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 H2AP "CXorf27, HIP17, HYPM" ENSG00000187516 "H2A.P histone" O75409 X 37990779-37991314 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 28 "testis: 44.2" "Cell type enriched" "Detected in single" 5 "Syncytiotrophoblasts: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 4 "SuSa: 1.2" "Not detected" "Not detected" HPA003356 Enhanced NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 12: NES - Nervous system development" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "HPA003356: AB_1078593" "unprognostic (2.99e-2)" 0.0 0.0 0.4 0.0 1.3 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.6 0.1 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 44.2 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.3 0.0 0.4 0.8 0.6 0.2 0.2 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 H2BC12 "H2BFAiii, H2BFT, HIST1H2BK" ENSG00000197903 "H2B clustered histone 12" O60814 6 27146361-27146855 "Predicted intracellular proteins" "Antibiotic, Antimicrobial, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 1.2;Extravillous trophoblasts: 3.4;Hofbauer cells: 1.1;Syncytiotrophoblasts: 3.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 1269.7;SiHa: 771.0;U-2 OS: 949.9;U-266/84: 1355.8" "HPA042205, HPA043013, HPA048671" Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 16: U-266 - Nucleosome" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm Cytosol "HPA042205: AB_2677900, HPA043013: AB_2678269, HPA048671: AB_2680488" "unprognostic (1.78e-2)" "unprognostic (4.70e-3)" "unprognostic (9.00e-3)" "unprognostic (1.30e-1)" "unprognostic (3.81e-1)" "unprognostic (4.50e-2)" "unprognostic (6.50e-2)" "unprognostic (4.27e-2)" "unprognostic (2.15e-1)" "unprognostic (1.29e-3)" "unprognostic (3.46e-3)" "unprognostic (9.49e-2)" "prognostic unfavorable (5.77e-5)" "unprognostic (3.93e-2)" "unprognostic (1.49e-1)" "unprognostic (7.59e-2)" "unprognostic (2.37e-2)" 45.2 28.9 10.3 35.9 13.4 46.4 31.2 8.1 13.1 46.1 15.1 45.7 41.6 35.2 27.7 64.2 59.9 37.7 32.1 12.2 11.1 31.3 94.0 47.1 59.6 13.3 12.3 28.9 60.0 14.8 16.2 44.7 12.9 75.1 26.4 0.4 43.1 21.7 8.5 30.3 44.8 22.1 15.7 66.9 56.0 44.6 13.6 65.7 49.2 6.7 24.2 35.0 42.8 21.6 64.6 153.7 25.7 41.2 116.0 37.0 84.7 118.1 70.5 157.9 99.1 133.1 68.9 28.1 338.6 64.2 94.1 78.3 29.8 35.8 19.7 95.1 201.2 42.0 91.0 4.4 46.2 29.9 183.4 205.0 26.8 29.5 28.1 38.8 27.6 14.1 1269.7 194.4 66.5 166.3 49.1 52.6 20.2 204.6 98.8 27.9 24.2 265.9 55.2 23.4 124.1 74.2 771.0 178.6 56.9 18.9 473.7 29.8 41.6 57.6 949.9 54.0 18.8 293.6 1355.8 207.7 34.7 314.1 34.5 244.6 49.0 329.3 21.6 45.3 19.6 112.1 21.3 21.9 53.1 141.9 25.7 20.4 308.2 28.5 96.3 120.8 65.7 68.3 10.3 13.4 8.1 13.1 12.2 11.1 13.3 12.3 12.9 15.7 13.6 21.6 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 1.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 3.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.1 0.0 0.0 0.0 HABP4 "IHABP4, SERBP1L" ENSG00000130956 "Hyaluronan binding protein 4" Q5JVS0 9 96450169-96491336 "Predicted intracellular proteins" "mRNA processing, mRNA splicing, Transcription, Transcription regulation, Translation regulation" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 73.3" "Group enriched" "Detected in many" 10 "Early spermatids: 224.6;Late spermatids: 808.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "B-cells: 1.9;T-cells: 1.6" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055969, HPA062366" Enhanced Supported "Nuclear membrane,Cytosol" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "Nuclear membrane" Cytosol "HPA055969: AB_2682991, HPA062366: " "unprognostic (1.67e-1)" "unprognostic (7.99e-2)" "unprognostic (2.12e-3)" "unprognostic (2.40e-1)" "unprognostic (1.77e-1)" "unprognostic (5.91e-2)" "unprognostic (1.36e-2)" "unprognostic (3.63e-2)" "unprognostic (3.49e-1)" "unprognostic (2.42e-2)" "unprognostic (1.75e-3)" "unprognostic (1.36e-1)" "prognostic favorable (1.10e-7)" "unprognostic (2.25e-1)" "unprognostic (1.40e-1)" "unprognostic (4.93e-2)" "unprognostic (3.62e-2)" 21.9 12.8 62.7 7.0 70.1 1.8 16.8 55.1 73.3 16.1 40.8 19.2 3.0 13.5 7.0 7.6 13.5 8.8 28.1 62.3 63.9 27.0 7.6 10.8 8.3 66.2 65.4 15.6 6.6 12.9 22.6 3.5 66.1 12.5 4.2 16.0 6.2 11.1 16.8 9.5 10.4 9.7 59.5 7.5 12.5 43.9 61.3 4.6 13.7 13.4 5.3 18.4 13.0 68.9 14.8 16.6 20.6 22.3 44.7 37.9 14.6 19.5 21.8 14.5 15.7 24.9 24.0 7.5 9.4 29.4 45.9 10.6 17.4 3.7 11.6 9.0 10.3 2.9 7.8 42.0 22.7 0.7 3.0 15.5 6.7 16.5 13.0 21.9 10.4 8.4 3.4 21.6 26.4 15.2 0.3 4.6 9.6 20.5 15.8 7.6 17.9 0.3 24.8 6.4 13.0 8.8 10.6 6.2 32.5 15.2 4.5 3.2 17.8 19.8 4.6 36.6 16.8 13.2 14.0 3.3 15.9 5.9 29.8 0.0 0.0 0.0 0.5 0.1 0.5 1.9 1.6 1.3 0.0 1.1 1.1 1.1 0.1 0.4 0.3 0.0 1.3 0.2 62.7 70.1 55.1 73.3 62.3 63.9 66.2 65.4 66.1 59.5 61.3 68.9 22.2 0.0 7.4 27.1 5.9 11.5 10.8 0.9 4.0 22.6 3.8 6.9 11.0 14.3 5.5 18.4 0.0 2.5 5.5 0.9 17.6 4.7 224.6 7.3 9.0 14.6 13.1 0.8 47.4 5.8 7.4 13.3 1.5 8.1 1.3 13.0 15.0 6.3 6.6 23.5 33.2 0.9 4.1 1.3 9.3 808.8 13.7 6.0 17.8 10.3 2.7 22.2 3.1 18.6 37.5 6.3 0.0 23.7 5.1 10.0 1.1 43.7 1.8 15.6 6.6 5.8 26.4 26.8 15.4 0.9 8.0 1.4 13.3 3.0 1.3 6.0 HACD1 "CAP, PTPLA" ENSG00000165996 "3-hydroxyacyl-CoA dehydratase 1" B0YJ81 10 17589032-17617374 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "Developmental protein, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 73.0" "Cell type enriched" "Detected in many" 4 "Cardiomyocytes: 143.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 11 "T-reg: 55.7" "Lineage enriched" "Detected in many" 12 "T-cells: 55.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (2.73e-2)" "unprognostic (3.26e-2)" "unprognostic (3.54e-1)" "unprognostic (2.62e-2)" "unprognostic (4.10e-1)" "unprognostic (5.67e-3)" "unprognostic (4.21e-2)" "unprognostic (3.04e-2)" "unprognostic (2.38e-1)" "unprognostic (1.70e-2)" "unprognostic (2.61e-2)" "unprognostic (3.43e-1)" "unprognostic (2.46e-2)" "unprognostic (2.93e-2)" "unprognostic (3.40e-2)" "unprognostic (1.10e-1)" "unprognostic (6.49e-2)" 9.7 7.0 3.1 5.0 3.5 8.0 8.8 10.7 4.6 6.8 2.9 31.9 2.8 22.1 3.3 7.8 10.3 3.6 73.0 3.0 6.5 5.0 1.6 9.7 1.3 5.5 5.2 4.3 2.7 0.5 3.7 1.6 5.0 11.9 3.8 2.3 2.7 16.7 36.5 3.0 6.9 25.4 2.4 1.7 15.0 3.5 4.7 2.6 7.6 16.5 1.2 18.1 6.8 8.4 29.3 24.6 6.8 33.4 30.1 5.8 0.6 40.5 24.4 51.9 48.5 16.4 34.6 0.2 5.9 66.4 74.5 7.1 17.3 12.3 28.6 19.1 10.4 67.1 18.4 45.6 39.0 0.3 4.8 14.0 17.2 29.9 11.6 39.8 10.1 35.1 0.6 1.3 69.0 21.0 50.4 6.7 14.6 2.2 6.6 44.7 7.1 0.8 20.5 5.6 7.5 19.1 34.6 0.6 58.9 21.2 24.2 16.7 9.8 30.3 17.4 18.7 18.8 0.9 0.8 0.3 22.3 7.7 4.3 4.7 0.9 0.7 1.2 0.1 0.3 0.4 5.0 1.0 3.0 1.3 0.9 0.7 2.6 3.3 0.3 1.5 55.7 1.3 3.1 3.5 10.7 4.6 3.0 6.5 5.5 5.2 5.0 2.4 4.7 8.4 2.4 28.9 15.0 0.3 0.4 0.0 23.1 0.0 8.0 0.8 6.9 21.6 143.7 10.0 2.5 31.3 0.0 0.5 4.4 0.4 3.9 16.5 11.1 5.6 8.0 5.4 3.6 29.2 10.4 8.0 1.9 7.1 8.2 12.4 6.3 17.5 20.7 1.0 5.4 0.0 11.7 2.5 0.0 2.2 0.0 2.7 1.8 3.6 0.0 5.6 0.8 0.5 1.0 2.5 31.8 15.6 0.8 0.7 0.6 23.9 0.5 2.3 0.7 0.6 0.0 5.7 32.5 7.4 5.2 17.7 0.0 3.0 2.9 10.8 3.5 6.2 HACD2 PTPLB ENSG00000206527 "3-hydroxyacyl-CoA dehydratase 2" Q6Y1H2 3 123490820-123585053 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SiHa: 249.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB019282 Approved NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 59: Non-specific - Transcription" "CAB019282: " "unprognostic (3.04e-2)" "unprognostic (2.51e-1)" "unprognostic (6.11e-2)" "unprognostic (2.65e-3)" "unprognostic (5.36e-2)" "unprognostic (6.04e-2)" "unprognostic (1.32e-2)" "unprognostic (1.95e-2)" "unprognostic (1.96e-1)" "unprognostic (1.22e-1)" "prognostic unfavorable (9.59e-5)" "unprognostic (6.90e-2)" "unprognostic (7.03e-3)" "unprognostic (1.48e-1)" "unprognostic (3.85e-2)" "unprognostic (1.94e-2)" "unprognostic (2.59e-2)" 68.3 11.2 16.2 16.5 23.5 8.7 22.8 19.3 20.5 14.6 8.4 26.7 29.9 16.6 17.7 18.9 13.1 16.7 10.7 16.0 19.7 24.1 48.4 19.4 21.3 19.4 17.1 12.5 17.4 21.3 7.7 15.5 21.0 29.5 27.7 13.8 16.4 12.9 5.3 32.5 25.8 16.7 17.8 12.3 21.2 19.0 16.6 14.9 19.4 8.4 28.6 14.7 17.1 33.9 76.9 42.7 28.8 21.1 88.3 19.5 106.5 53.7 22.2 54.6 39.4 87.9 66.1 44.1 37.8 51.7 63.3 162.8 52.3 67.4 57.3 28.3 17.5 30.8 37.3 68.9 28.7 41.2 29.4 27.2 169.7 26.5 73.6 85.2 29.0 30.0 6.3 42.7 33.4 59.8 19.7 12.3 37.2 92.7 37.4 29.6 31.6 46.9 66.5 48.6 50.5 15.8 249.9 52.7 34.6 41.5 54.9 21.1 22.7 56.8 42.2 57.5 53.1 25.2 34.7 35.9 25.5 28.5 31.1 0.7 1.6 1.1 1.5 1.2 2.2 1.5 1.9 1.9 2.8 2.0 1.8 1.7 0.5 1.3 1.0 1.6 2.5 1.2 16.2 23.5 19.3 20.5 16.0 19.7 19.4 17.1 21.0 17.8 16.6 33.9 19.8 6.4 43.1 8.8 17.5 0.0 28.7 0.0 23.9 9.5 27.8 21.5 13.5 22.8 15.5 46.0 6.2 21.5 18.9 29.4 7.9 15.4 19.8 22.3 14.9 17.0 15.8 15.4 34.3 18.7 16.5 17.3 25.0 35.7 3.8 17.1 16.8 47.5 22.9 1.7 29.7 16.4 0.0 24.2 0.0 10.4 11.5 25.1 0.0 12.2 19.6 14.5 19.6 25.1 32.6 19.6 16.6 17.7 15.0 40.6 33.8 17.8 2.9 13.9 6.6 14.8 11.3 10.5 24.8 35.1 0.0 6.7 14.2 11.8 19.9 33.2 HAPLN3 "EXLD1, HsT19883" ENSG00000140511 "Hyaluronan and proteoglycan link protein 3" Q96S86 15 88877294-88895597 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 9 "Extravillous trophoblasts: 966.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 50.9" "Lineage enriched" "Detected in all" 5 "T-cells: 50.9" "Cell line enhanced" "Detected in many" "HDLM-2: 34.7;U-2 OS: 31.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA039237 Approved Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 64: Macrophages - Immune response" "Cluster 9: U-2 OS - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane, Cytosol" "HPA039237: AB_10805357" "unprognostic (1.67e-2)" "unprognostic (1.04e-3)" "unprognostic (2.57e-1)" "unprognostic (2.53e-2)" "unprognostic (3.27e-1)" "unprognostic (2.24e-2)" "unprognostic (4.21e-1)" "unprognostic (3.82e-1)" "unprognostic (3.37e-3)" "unprognostic (7.37e-3)" "unprognostic (1.13e-3)" "unprognostic (4.30e-1)" "prognostic unfavorable (4.18e-13)" "unprognostic (1.95e-1)" "unprognostic (3.01e-2)" "unprognostic (6.12e-2)" "unprognostic (1.12e-1)" 10.3 1.9 2.1 11.5 2.0 3.1 8.6 1.9 2.7 5.1 2.1 3.2 0.6 4.3 0.1 6.1 6.2 2.7 4.6 2.1 2.0 6.1 0.9 9.7 11.7 2.4 2.1 2.7 1.4 0.5 2.2 1.4 2.5 5.7 0.4 4.2 6.0 0.7 3.6 6.2 4.6 2.7 2.3 5.7 3.5 1.0 2.4 2.9 4.6 0.6 3.2 6.9 5.6 2.1 2.0 7.0 1.3 15.4 4.4 4.2 4.7 4.4 1.0 1.6 2.0 4.4 6.4 0.0 11.9 5.4 2.5 1.7 14.7 1.9 0.0 34.7 12.9 4.9 0.3 0.0 0.6 0.0 0.1 1.6 0.8 3.0 0.2 0.2 7.1 0.6 0.1 9.3 0.8 0.2 0.1 0.0 11.2 0.0 0.2 0.0 0.6 11.5 2.9 0.1 0.1 4.2 0.9 0.7 6.1 1.9 0.0 0.6 1.3 10.8 31.2 8.1 0.7 1.1 0.1 0.1 3.8 0.0 9.3 1.4 1.1 0.0 1.2 0.8 5.4 0.2 18.3 7.4 2.2 1.5 18.3 8.6 0.3 10.1 0.2 0.8 50.9 5.9 2.1 2.0 1.9 2.7 2.1 2.0 2.4 2.1 2.5 2.3 2.4 2.1 16.0 0.0 3.4 1.3 4.0 32.0 10.8 13.5 4.6 2.5 47.1 42.4 9.3 1.5 10.4 1.8 10.4 5.8 3.2 0.5 0.0 5.3 0.0 6.3 3.7 29.4 0.0 0.0 1.3 2.0 966.2 8.5 1.5 12.1 1.3 2.5 3.3 0.1 19.3 0.0 0.1 0.9 6.1 0.3 22.0 0.2 0.9 3.0 17.8 2.8 9.7 3.8 3.1 0.5 0.1 9.9 0.1 0.7 0.5 10.4 0.0 0.2 2.7 103.8 13.1 7.2 24.5 0.3 2.1 6.3 24.2 20.4 9.4 0.2 0.5 7.8 HASPIN GSG2 ENSG00000177602 "Histone H3 associated protein kinase" Q8TF76 17 3723903-3726699 "Enzymes, Predicted intracellular proteins" "Cell cycle" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.0;lymphoid tissue: 5.3;testis: 7.3" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 1.2;Extravillous trophoblasts: 3.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "HPA027422, HPA030698" Approved Supported Nucleoplasm NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA027422: AB_10601812, HPA030698: AB_2673575" "unprognostic (1.15e-2)" "unprognostic (2.78e-2)" "unprognostic (7.06e-2)" "unprognostic (2.14e-2)" "unprognostic (8.05e-2)" "unprognostic (2.81e-1)" "unprognostic (1.01e-4)" "unprognostic (1.57e-2)" "unprognostic (6.60e-2)" "unprognostic (1.77e-1)" "unprognostic (2.75e-3)" "unprognostic (3.82e-3)" "unprognostic (0.00e+0)" "unprognostic (5.65e-3)" "unprognostic (3.09e-2)" "unprognostic (1.31e-1)" "unprognostic (1.73e-1)" 0.2 0.1 0.0 1.8 0.2 6.0 0.4 0.0 0.1 0.2 0.2 1.1 1.5 0.2 0.1 1.3 0.3 0.2 0.1 0.0 0.0 0.1 0.1 1.4 4.2 0.1 0.1 0.1 0.2 0.0 0.0 0.6 0.1 0.3 1.0 0.0 0.4 0.0 0.6 0.7 1.8 0.4 0.0 1.7 0.9 7.3 0.2 5.3 0.3 0.1 5.1 0.3 0.5 0.2 11.3 12.2 11.1 12.5 0.7 1.4 9.3 10.2 7.8 19.7 19.3 9.6 4.6 27.7 5.7 5.7 7.9 18.0 20.1 9.9 18.7 0.1 16.7 13.8 9.9 5.8 0.5 8.1 13.7 0.9 0.8 14.9 9.2 2.4 9.1 21.6 12.4 23.7 10.1 5.9 16.4 4.8 9.8 8.7 8.3 16.8 13.9 7.4 3.0 7.8 4.4 6.5 8.9 6.1 3.5 9.6 6.1 7.5 4.7 8.7 9.9 9.8 18.1 4.5 5.4 13.4 5.1 11.5 10.7 0.1 0.1 0.5 0.0 0.1 0.0 0.1 0.1 0.0 0.2 0.5 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 3.3 0.2 0.0 0.2 0.0 0.9 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 HCAR1 "FKSG80, GPR104, GPR81, HCA1, LACR1, TA-GPCR" ENSG00000196917 "Hydroxycarboxylic acid receptor 1" Q9BXC0 12 122726076-122730844 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "breast: 11.5;parathyroid gland: 40.4" "Group enriched" "Detected in some" 4 "Breast glandular cells: 8.7;Breast myoepithelial cells: 5.2;Club cells: 3.2;Early spermatids: 9.6;Extravillous trophoblasts: 3.7;Late spermatids: 6.5" "Cancer enhanced" "Detected in many" "breast cancer: 7.9" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "basophil: 2.0" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.0" "Cell line enhanced" "Detected in some" "CAPAN-2: 12.1;MCF7: 8.1;RT4: 35.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 15: RT4 - Unknown function" "Cluster 35: Glandular cells - Unknown function" "prognostic unfavorable (3.61e-5)" "unprognostic (8.90e-2)" "unprognostic (1.62e-1)" "unprognostic (1.31e-2)" "unprognostic (1.93e-2)" "unprognostic (3.80e-4)" "unprognostic (5.43e-4)" "unprognostic (1.41e-1)" "unprognostic (7.74e-2)" "unprognostic (2.22e-1)" "unprognostic (6.85e-3)" "unprognostic (1.26e-1)" "unprognostic (2.66e-3)" "unprognostic (2.14e-2)" "unprognostic (2.51e-1)" "unprognostic (2.38e-1)" "unprognostic (1.87e-2)" 5.5 0.3 0.4 0.2 0.4 1.0 11.5 1.7 0.7 0.7 0.4 0.1 0.3 0.4 1.2 0.2 1.7 0.2 0.2 0.6 0.1 0.8 0.1 0.4 0.4 0.3 0.1 0.4 0.1 40.4 0.3 1.0 0.3 1.0 0.1 0.6 5.0 5.1 1.2 0.7 0.3 0.2 0.1 2.3 2.0 0.8 0.2 0.3 1.3 0.1 0.1 1.2 0.3 1.2 0.1 0.3 0.2 0.3 0.0 0.0 1.9 0.1 0.0 0.0 0.1 2.5 12.1 0.3 0.4 0.0 0.2 0.3 0.0 0.0 0.0 0.1 0.2 0.2 0.6 1.8 0.2 0.3 0.2 0.6 0.0 0.6 0.0 0.1 0.0 0.2 0.2 0.6 0.1 8.1 0.2 0.4 0.3 3.0 0.6 0.3 0.2 0.3 0.1 35.3 2.6 0.2 0.1 4.2 0.0 0.3 3.4 0.1 0.3 0.4 0.2 0.2 0.2 0.4 0.1 0.4 0.2 0.2 0.3 2.0 0.2 0.2 0.2 0.1 0.2 0.2 0.2 0.2 0.0 0.4 0.2 0.2 1.2 0.4 0.1 0.3 0.1 0.1 0.4 0.4 1.7 0.7 0.6 0.1 0.3 0.1 0.3 0.1 0.2 1.2 1.3 0.0 0.5 0.0 0.0 0.1 1.4 0.2 0.0 0.3 8.7 5.2 0.4 0.0 3.2 0.0 0.0 0.4 0.3 0.0 0.0 0.0 9.6 0.2 0.2 0.3 0.0 0.0 0.0 0.0 3.7 0.3 0.0 0.3 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.7 6.5 0.3 0.3 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.1 0.0 0.1 1.0 0.0 0.2 0.0 0.0 0.3 0.2 0.0 0.0 1.0 HCK JTK9 ENSG00000101336 "HCK proto-oncogene, Src family tyrosine kinase" P08631 20 32052197-32101856 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Exocytosis, Host-virus interaction, Immunity, Inflammatory response, Innate immunity, Phagocytosis" "Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 112.1" "Cell type enhanced" "Detected in many" "Hofbauer cells: 150.7;Kupffer cells: 155.5;Langerhans cells: 89.2;Macrophages: 170.1;Microglial cells: 52.5;monocytes: 222.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "classical monocyte: 575.0;eosinophil: 707.8;intermediate monocyte: 1059.1;myeloid DC: 336.3;neutrophil: 801.3;non-classical monocyte: 1251.7" "Group enriched" "Detected in all" 16 "dendritic cells: 336.3;granulocytes: 801.3;monocytes: 1251.7" "Group enriched" "Detected in some" 9 "THP-1: 69.3;U-937: 199.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB005195, HPA035534, HPA063768" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "Plasma membrane, Cytosol" "CAB005195: AB_631619, HPA035534: , HPA063768: AB_2685118" "unprognostic (6.22e-2)" "unprognostic (6.16e-3)" "unprognostic (2.26e-2)" "unprognostic (7.98e-2)" "unprognostic (8.83e-2)" "unprognostic (5.50e-2)" "unprognostic (4.09e-2)" "unprognostic (1.72e-2)" "unprognostic (4.34e-2)" "unprognostic (1.59e-1)" "unprognostic (4.08e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (1.66e-4)" "unprognostic (4.92e-2)" "unprognostic (4.42e-2)" "unprognostic (6.95e-2)" "unprognostic (1.12e-1)" 24.8 9.2 4.7 100.0 5.0 55.2 6.0 5.5 6.0 5.5 13.7 12.8 15.2 3.1 2.6 6.7 7.6 14.4 4.8 4.7 6.2 4.7 14.1 46.0 38.6 9.9 6.8 2.5 4.5 2.1 3.1 20.9 8.3 4.0 13.6 0.5 5.1 4.7 1.6 5.8 17.8 25.3 8.1 112.1 6.7 2.3 8.4 14.5 2.8 6.9 39.3 32.8 4.1 12.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.9 0.0 0.1 0.1 1.3 0.0 0.0 0.1 0.0 4.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 15.6 0.0 0.1 0.1 4.9 0.4 0.0 0.0 0.4 0.2 0.6 0.0 0.0 0.3 0.0 0.5 0.0 0.2 0.7 0.0 69.3 0.0 0.0 0.3 0.0 0.1 1.9 0.3 10.3 0.0 199.6 0.0 6.4 575.0 707.8 1.1 1059.1 1.3 48.4 1.1 1.1 336.3 43.0 1.1 0.9 801.3 11.0 1251.7 30.4 1.2 566.4 4.7 5.0 5.5 6.0 4.7 6.2 9.9 6.8 8.3 8.1 8.4 12.0 0.6 6.4 14.0 0.0 17.1 3.1 4.0 0.2 0.6 0.1 0.4 1.3 2.0 1.5 3.9 7.3 0.0 0.9 12.1 0.2 1.9 0.1 2.5 0.1 0.1 3.7 1.8 1.7 1.2 0.6 0.9 1.3 4.6 0.1 6.3 0.1 1.1 2.3 150.7 0.0 1.0 0.5 22.4 155.5 89.2 0.3 0.0 170.1 1.8 52.5 222.0 0.0 4.1 1.5 0.6 0.0 0.0 0.0 0.7 0.5 0.1 0.3 1.5 0.1 0.0 0.6 0.5 0.2 0.3 0.2 1.1 1.6 3.0 0.2 0.9 3.7 HCN4 ENSG00000138622 "Hyperpolarization activated cyclic nucleotide gated potassium channel 4" Q9Y3Q4 15 73319859-73368958 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Sodium transport, Transport" "Ion channel, Ligand-gated ion channel, Potassium channel, Sodium channel, Voltage-gated channel" "Brugada syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 16 "brain: 8.5;heart muscle: 8.4;testis: 7.2" "Group enriched" "Detected in some" 5 "Early spermatids: 29.4;Late spermatids: 49.5" "Cancer enriched" "Detected in some" 4 "testis cancer: 3.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 1.3;CACO-2: 1.7;HDLM-2: 1.1;NTERA-2: 4.9;SuSa: 1.2;U-2 OS: 2.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA073174 Approved NA NA "Cluster 43: Testis - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 31: Spermatids - Spermatogenesis" "HPA073174: " "unprognostic (2.21e-1)" "unprognostic (1.39e-1)" "unprognostic (2.18e-2)" "unprognostic (3.14e-2)" "unprognostic (5.30e-3)" "unprognostic (1.92e-2)" "unprognostic (2.19e-1)" "unprognostic (3.50e-2)" "unprognostic (2.37e-1)" "unprognostic (6.56e-2)" "unprognostic (1.13e-3)" "unprognostic (1.13e-1)" "unprognostic (6.05e-5)" "unprognostic (5.56e-2)" "unprognostic (4.60e-2)" "unprognostic (1.51e-2)" "unprognostic (7.95e-2)" 0.0 0.4 3.6 0.0 0.7 0.0 0.0 2.2 1.8 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 8.4 1.0 2.8 0.0 0.0 0.0 0.0 5.0 4.2 0.0 0.1 0.0 0.5 0.0 4.6 0.1 0.0 0.4 0.0 0.3 0.0 0.0 0.1 0.0 2.5 0.0 0.1 7.2 8.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.1 0.0 0.7 0.0 0.3 0.1 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.2 0.0 0.0 1.2 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.7 2.2 1.8 1.0 2.8 5.0 4.2 4.6 2.5 8.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 29.4 0.6 0.0 0.2 1.8 0.0 1.5 0.2 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 49.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.7 1.2 0.0 0.0 0.3 1.6 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 HCST "DAP10, DKFZP586C1522, KAP10, PIK3AP" ENSG00000126264 "Hematopoietic cell signal transducer" Q9UBK5 19 35902529-35904377 "Metabolic proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "bone marrow: 253.7;lymphoid tissue: 115.6" "Cell type enhanced" "Detected in many" "dendritic cells: 993.2;Hofbauer cells: 571.1;Kupffer cells: 396.6;Langerhans cells: 584.5;Macrophages: 392.7;NK-cells: 1687.0;T-cells: 769.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 239.9;HL-60: 139.6;HMC-1: 154.3;THP-1: 177.8;U-937: 272.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB034435, HPA063026" Enhanced Supported "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Golgi apparatus, Plasma membrane" Vesicles "CAB034435: AB_2117803, HPA063026: " "unprognostic (1.40e-3)" "unprognostic (3.07e-2)" "unprognostic (3.04e-2)" "unprognostic (7.27e-3)" "unprognostic (1.23e-1)" "unprognostic (8.23e-3)" "unprognostic (1.85e-1)" "unprognostic (2.54e-1)" "prognostic favorable (6.70e-4)" "unprognostic (5.97e-2)" "unprognostic (1.94e-3)" "unprognostic (1.02e-1)" "prognostic unfavorable (1.59e-10)" "unprognostic (3.78e-1)" "unprognostic (3.25e-2)" "unprognostic (1.65e-1)" "unprognostic (1.56e-1)" 27.2 9.5 14.0 53.6 13.8 253.7 14.1 13.7 18.5 9.6 16.6 12.7 11.3 8.3 4.7 5.5 9.9 11.5 8.3 13.5 17.0 10.6 14.5 40.3 68.0 18.3 14.7 5.7 6.7 2.5 9.6 24.7 17.6 9.4 8.6 2.2 10.7 8.2 4.2 6.6 28.2 11.2 17.1 115.6 15.4 3.4 18.2 59.6 7.9 3.0 37.8 16.4 8.0 22.2 0.9 0.0 0.3 0.5 1.1 0.0 0.3 1.9 1.1 0.0 0.6 0.8 1.2 26.9 1.7 2.0 0.4 0.9 0.0 0.2 0.0 0.6 0.0 239.9 0.5 0.7 0.9 139.6 154.3 1.6 0.3 0.0 0.0 0.7 0.0 14.8 2.1 33.4 0.4 0.4 16.9 54.7 0.3 0.3 0.7 0.8 0.5 2.0 0.4 0.1 0.9 0.4 1.3 0.7 0.9 0.2 0.5 177.8 0.5 1.4 1.8 0.2 0.2 1.6 1.1 39.5 1.4 272.2 0.3 124.7 725.8 105.8 1583.4 546.1 1172.3 78.6 664.6 1293.3 409.8 51.0 550.6 1108.0 196.1 1290.7 314.4 823.7 629.9 1421.2 14.0 13.8 13.7 18.5 13.5 17.0 18.3 14.7 17.6 17.1 18.2 22.2 12.3 6.4 43.3 0.0 85.3 28.6 1.3 1.7 2.8 0.4 11.4 12.8 1.2 15.7 7.1 9.2 0.0 3.8 993.2 1.8 0.0 2.8 1.3 4.0 2.5 18.3 0.0 84.2 0.1 1.2 4.7 9.5 14.8 5.5 240.4 0.3 21.0 14.3 571.1 1.7 0.1 0.9 2.0 396.6 584.5 3.0 2.1 392.7 44.4 5.6 309.9 0.7 1687.0 0.0 0.1 1.0 1.4 0.0 97.7 0.6 2.0 6.1 5.1 2.2 19.7 4.2 6.2 2.2 4.9 2.7 21.0 6.0 769.9 1.0 2.7 1.2 HDAC4 "BDMR, HA6116, HD4, HDAC-4, HDAC-A, HDACA, KIAA0288" ENSG00000068024 "Histone deacetylase 4" P56524 2 239048168-239401654 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "Autism spectrum disorder, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 58.2" "Group enriched" "Detected in many" 4 "Astrocytes: 62.0;Early spermatids: 69.9;Excitatory neurons: 118.1;Inhibitory neurons: 84.9;Late spermatids: 59.0;Microglial cells: 38.4;Oligodendrocyte precursor cells: 85.5;Oligodendrocytes: 124.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 32.0;neutrophil: 47.7" "Lineage enriched" "Detected in many" 5 "granulocytes: 47.7" "Cell line enhanced" "Detected in many" "JURKAT: 49.1;MOLT-4: 48.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048723, HPA071448" Approved Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear speckles" "Nucleoplasm, Cytosol" "HPA048723: AB_2680501, HPA071448: " "unprognostic (1.54e-1)" "unprognostic (1.76e-2)" "unprognostic (1.33e-1)" "unprognostic (1.18e-3)" "unprognostic (2.43e-2)" "unprognostic (2.39e-3)" "unprognostic (3.06e-4)" "unprognostic (1.00e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (6.33e-4)" "prognostic favorable (1.13e-4)" "unprognostic (1.40e-1)" "unprognostic (4.82e-3)" "unprognostic (2.40e-1)" "unprognostic (3.26e-2)" "unprognostic (1.32e-2)" "unprognostic (6.04e-2)" 4.4 6.3 9.3 5.0 12.0 17.0 3.8 0.6 13.4 7.5 0.1 29.0 2.7 9.1 2.5 8.0 6.7 7.1 5.2 9.0 6.5 3.7 2.4 3.9 3.5 9.9 6.1 7.5 3.7 2.7 6.5 1.5 11.2 5.6 3.4 2.4 3.3 5.9 58.2 5.9 7.2 6.2 2.3 5.6 7.2 9.2 6.7 9.7 4.2 35.6 2.5 10.0 4.5 10.1 3.2 5.8 4.1 6.1 4.5 3.9 5.9 3.0 2.3 2.3 1.7 2.9 7.5 2.0 1.9 3.4 3.6 3.4 4.0 2.0 1.4 12.8 1.8 3.1 5.1 5.8 3.8 5.5 4.6 4.4 2.6 4.6 3.3 2.3 2.4 49.1 3.7 4.5 2.7 4.7 48.1 10.7 4.0 6.0 2.8 7.6 7.2 4.0 5.3 4.4 4.6 6.4 5.3 2.5 16.2 2.6 1.0 17.9 1.9 5.0 0.4 6.8 4.6 3.3 3.2 3.1 6.9 6.9 7.4 32.0 10.2 2.3 1.0 3.3 1.2 0.2 1.1 1.0 1.0 0.1 0.5 0.5 47.7 3.2 1.7 0.6 1.7 1.1 9.3 12.0 0.6 13.4 9.0 6.5 9.9 6.1 11.2 2.3 6.7 10.1 8.6 3.2 7.4 62.0 5.2 7.9 2.9 3.0 8.6 12.2 6.2 4.8 13.3 7.2 2.9 11.0 2.1 1.5 12.8 4.1 0.0 2.8 69.9 7.0 15.1 7.1 6.0 6.1 118.1 2.2 1.7 14.0 7.7 7.4 2.5 6.6 11.7 6.7 3.2 16.8 84.9 5.2 2.0 17.2 10.0 59.0 11.8 10.3 5.4 38.4 14.9 8.6 15.5 85.5 124.0 1.9 1.6 12.4 7.0 6.4 5.0 1.6 2.6 7.1 0.0 18.7 6.5 2.8 3.3 11.1 9.7 1.4 12.2 4.9 6.4 2.7 HEATR6 "ABC1, FLJ22087" ENSG00000068097 "HEAT repeat containing 6" Q6AI08 17 60041008-60078922 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MCF7: 64.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030789, HPA062157" Uncertain Approved Mitochondria NA NA "Cluster 37: B-cells - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA030789: AB_10601660, HPA062157: AB_2684700" "unprognostic (1.98e-1)" "unprognostic (7.95e-2)" "unprognostic (4.32e-1)" "prognostic unfavorable (2.03e-4)" "unprognostic (4.22e-1)" "unprognostic (1.00e-1)" "prognostic unfavorable (5.02e-6)" "unprognostic (2.24e-1)" "unprognostic (2.86e-1)" "unprognostic (1.97e-1)" "unprognostic (6.81e-3)" "unprognostic (9.84e-2)" "prognostic unfavorable (6.73e-4)" "unprognostic (5.01e-2)" "unprognostic (1.81e-1)" "unprognostic (5.50e-2)" "unprognostic (2.11e-1)" 4.5 7.2 5.3 2.1 6.0 3.1 4.3 6.8 5.9 6.7 4.4 7.4 1.8 7.1 3.2 4.6 6.6 1.9 5.1 5.1 5.3 4.1 3.6 5.0 3.0 6.2 5.4 7.7 5.1 3.4 7.3 2.7 6.2 5.7 2.3 5.2 5.2 3.5 6.0 5.5 6.1 2.7 5.4 7.2 4.9 4.9 5.8 3.0 4.6 2.4 2.2 6.5 5.2 7.8 4.8 13.0 9.5 7.5 5.1 9.1 6.9 4.5 8.9 8.8 9.7 5.2 3.6 1.8 7.8 8.0 7.1 4.9 5.6 6.0 11.9 4.1 7.2 9.3 8.8 9.7 5.6 7.0 10.1 7.1 8.8 6.4 7.6 9.5 4.7 6.0 5.9 5.1 6.6 64.6 8.9 3.6 5.9 3.9 8.7 3.2 16.9 5.8 5.7 7.1 5.4 13.7 4.6 1.6 6.6 8.2 7.9 5.6 4.5 8.9 15.0 8.2 8.4 6.5 7.1 0.1 7.6 5.1 6.9 2.4 3.4 3.4 3.4 5.4 3.2 8.2 2.5 2.5 6.0 4.3 3.3 2.6 0.5 3.0 5.6 2.9 2.9 2.7 5.3 6.0 6.8 5.9 5.1 5.3 6.2 5.4 6.2 5.4 5.8 7.8 4.6 12.8 6.3 9.4 8.0 0.9 2.8 6.2 6.2 11.1 3.1 5.0 9.2 2.8 8.1 7.3 10.4 5.7 5.0 1.1 3.9 4.8 1.0 4.8 9.1 5.1 6.7 3.0 13.1 3.3 3.4 7.4 6.6 4.3 11.4 8.8 4.2 2.8 4.6 6.7 13.7 1.5 4.1 5.6 2.6 0.7 3.4 8.5 1.8 15.9 15.3 8.8 7.2 16.6 25.3 2.9 1.0 11.3 3.3 1.7 1.5 3.3 10.5 6.6 6.6 6.5 15.4 5.1 7.7 3.6 2.3 2.1 7.6 10.1 3.1 1.2 HELZ "DHRC, HUMORF5, KIAA0054" ENSG00000198265 "Helicase with zinc finger" P42694 17 67070444-67245989 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028276 Approved Approved "Nucleoli,Nucleoli rim,Plasma membrane,Actin filaments" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoli, Nucleoli rim" "Plasma membrane, Actin filaments" "HPA028276: AB_10601814" "unprognostic (3.16e-1)" "unprognostic (2.10e-2)" "unprognostic (7.56e-3)" "unprognostic (1.29e-1)" "unprognostic (4.83e-2)" "unprognostic (4.71e-2)" "unprognostic (5.85e-2)" "unprognostic (5.31e-2)" "unprognostic (3.60e-2)" "unprognostic (1.16e-1)" "unprognostic (1.51e-1)" "unprognostic (4.98e-2)" "unprognostic (1.33e-3)" "unprognostic (1.42e-1)" "unprognostic (1.24e-1)" "unprognostic (1.59e-1)" "unprognostic (1.31e-1)" 6.3 6.6 3.8 8.5 4.9 12.5 6.6 12.0 5.7 7.6 8.4 5.8 4.8 7.4 6.1 4.7 6.1 7.1 6.1 3.6 6.9 6.9 10.9 6.8 9.8 4.1 5.2 12.3 7.8 12.0 6.1 11.2 4.0 6.1 6.6 14.3 6.2 6.2 9.1 4.4 5.9 7.5 3.3 9.1 6.5 10.8 5.5 15.4 8.7 14.0 8.9 6.6 5.0 3.3 10.3 10.0 12.3 12.3 14.8 8.4 18.7 9.0 8.8 11.8 12.4 14.7 7.9 21.2 7.2 12.0 7.4 10.5 23.3 11.3 18.4 8.2 7.3 27.2 10.7 12.5 7.1 22.3 15.6 9.8 10.5 11.4 14.1 8.8 18.1 15.6 19.1 12.9 9.8 13.0 29.0 7.6 7.4 9.2 9.7 19.3 21.6 9.2 9.1 14.3 12.0 11.0 14.3 11.5 15.2 16.9 13.7 13.7 16.1 14.5 16.6 8.0 8.1 10.7 13.4 15.5 7.2 13.7 15.5 2.3 3.3 2.8 5.1 2.8 6.3 1.7 3.1 3.2 2.8 2.8 1.9 2.6 2.3 2.6 1.9 2.2 3.0 2.3 3.8 4.9 12.0 5.7 3.6 6.9 4.1 5.2 4.0 3.3 5.5 3.3 42.9 19.2 37.1 89.1 44.3 32.1 24.6 30.2 29.6 50.8 32.8 23.6 31.1 24.3 30.2 27.6 93.8 32.9 95.8 29.4 7.9 19.1 5.2 49.4 55.8 32.3 38.3 48.8 93.1 14.2 42.8 30.9 38.7 118.5 33.7 51.9 61.8 52.1 31.9 67.3 112.1 30.2 16.2 79.4 28.8 10.5 38.8 55.4 14.2 107.7 62.0 24.0 104.0 134.2 72.6 19.2 23.1 42.9 67.1 29.3 27.7 14.6 26.1 54.9 13.1 45.9 34.0 36.0 26.0 33.6 20.2 18.3 71.0 32.6 26.3 45.8 HELZ2 "KIAA1769, PDIP1, PRIC285" ENSG00000130589 "Helicase with zinc finger 2" Q9BYK8 20 63558086-63574239 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Granulosa cells: 46.1;Urothelial cells: 47.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 59.4;GAMG: 34.5;SK-MEL-30: 25.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA051267 Uncertain NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 40: Granulosa cells - Unknown function" "HPA051267: " "unprognostic (1.86e-1)" "unprognostic (7.75e-2)" "unprognostic (2.41e-1)" "unprognostic (1.93e-3)" "unprognostic (1.35e-1)" "unprognostic (1.44e-1)" "unprognostic (2.21e-1)" "unprognostic (1.36e-2)" "unprognostic (5.06e-2)" "unprognostic (1.52e-1)" "unprognostic (1.73e-2)" "unprognostic (3.61e-2)" "unprognostic (2.19e-3)" "unprognostic (3.95e-2)" "prognostic unfavorable (4.92e-4)" "unprognostic (9.76e-2)" "unprognostic (1.16e-1)" 6.6 4.2 4.0 5.6 2.9 15.6 5.6 2.3 2.1 5.7 1.6 5.5 3.8 4.2 0.6 7.4 5.0 3.0 7.0 1.9 2.6 6.6 7.7 9.9 4.8 6.2 3.1 3.9 5.8 0.8 5.1 2.3 4.1 4.6 0.9 0.1 12.2 1.1 1.8 4.8 6.3 1.0 6.4 12.3 7.6 1.2 4.7 3.0 5.9 0.9 1.8 3.9 3.9 2.7 10.0 3.7 1.2 3.7 2.2 2.8 7.1 3.5 5.2 59.4 23.0 10.1 12.4 0.2 7.5 1.3 34.5 15.3 0.7 3.6 2.3 3.7 1.7 0.2 4.6 3.5 4.8 0.3 23.4 3.5 2.5 4.3 0.7 1.3 2.8 0.2 1.8 4.1 0.7 9.9 1.1 10.2 1.9 2.6 11.4 2.2 2.0 3.9 1.7 11.4 0.9 3.3 10.9 0.7 25.4 0.7 3.4 3.0 4.5 5.7 8.4 4.7 3.6 5.2 0.7 0.2 6.2 1.6 5.2 0.0 0.1 0.4 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 4.0 2.9 2.3 2.1 1.9 2.6 6.2 3.1 4.1 6.4 4.7 2.7 24.7 9.6 6.0 0.3 10.5 8.7 22.7 8.8 4.6 1.0 8.8 5.5 4.5 8.6 12.1 9.2 0.0 2.1 15.9 26.0 0.0 8.8 0.1 11.6 9.6 24.9 30.9 3.2 0.1 7.7 13.4 11.6 26.0 17.5 0.0 46.1 10.4 6.0 3.5 0.0 0.3 19.5 4.1 4.3 17.1 0.0 7.2 10.8 3.6 4.7 7.0 1.7 24.7 1.0 0.4 20.4 20.7 2.2 6.4 28.9 17.9 0.8 9.6 2.7 6.6 12.2 9.9 0.7 0.3 5.1 8.4 1.9 14.7 17.7 14.5 47.4 HEXIM1 "CLP-1, EDG1, HIS1, MAQ1" ENSG00000186834 "HEXIM P-TEFb complex subunit 1" O94992 17 45148475-45152099 "Predicted intracellular proteins" "Immunity, Innate immunity, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 467.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008926, CAB011625" Supported Enhanced Nucleoplasm,Vesicles NA NA "Cluster 10: Basophils - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 20: HeLa - Mitochondria" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Vesicles "CAB011625: AB_2233058, HPA008926: AB_1079048" "unprognostic (2.82e-2)" "unprognostic (1.08e-1)" "unprognostic (1.15e-1)" "unprognostic (2.72e-2)" "unprognostic (2.39e-1)" "unprognostic (2.27e-1)" "unprognostic (1.10e-1)" "unprognostic (1.34e-2)" "unprognostic (4.74e-2)" "unprognostic (1.44e-1)" "unprognostic (2.32e-2)" "unprognostic (1.20e-2)" "unprognostic (1.83e-2)" "unprognostic (2.77e-1)" "unprognostic (1.58e-1)" "unprognostic (2.89e-3)" "unprognostic (1.26e-2)" 16.8 32.6 16.3 13.2 15.4 36.3 17.0 16.2 16.5 17.2 16.5 22.5 17.7 19.6 15.9 24.2 21.3 14.3 15.0 14.8 16.8 21.1 26.8 17.3 12.8 17.0 19.1 14.4 19.7 14.1 19.2 25.2 16.0 24.2 10.2 9.0 19.2 19.8 33.2 22.6 24.9 13.0 17.7 25.6 23.1 21.6 19.7 15.4 20.1 21.6 12.4 19.7 17.6 14.2 35.7 111.1 22.8 33.0 36.7 19.6 55.3 30.9 27.8 25.0 27.8 52.6 49.3 15.5 93.1 32.7 12.1 28.2 13.8 30.4 20.0 32.2 32.9 48.2 65.8 65.0 32.0 30.3 61.4 23.0 25.5 18.6 8.1 62.6 12.7 26.8 21.5 36.6 19.0 47.8 31.9 34.9 20.9 32.9 33.4 13.1 19.9 19.2 66.5 62.1 12.2 9.2 46.6 52.0 52.2 23.0 54.2 23.5 24.3 25.1 34.6 14.6 58.5 33.1 11.4 10.0 23.0 28.1 29.1 16.2 4.0 6.8 4.2 6.1 2.4 3.0 4.2 3.7 3.3 3.2 3.7 3.9 10.0 3.7 7.3 3.4 3.8 2.2 16.3 15.4 16.2 16.5 14.8 16.8 17.0 19.1 16.0 17.7 19.7 14.2 210.3 73.7 111.8 7.2 76.1 84.5 75.0 57.7 157.1 25.1 127.0 215.9 59.7 87.2 60.5 25.8 22.9 134.8 114.3 250.4 7.9 35.0 2.2 88.8 66.1 91.3 52.8 82.1 10.7 23.6 70.1 99.2 94.3 137.9 125.9 16.5 42.5 40.5 42.1 15.2 12.9 122.0 54.9 33.9 83.2 3.0 35.1 83.0 53.4 9.4 38.4 27.7 28.8 7.1 8.2 25.3 127.1 43.6 44.1 52.1 184.9 53.8 45.7 24.8 26.3 249.2 128.2 2.6 7.9 126.7 71.5 467.5 111.1 16.9 92.2 34.4 HID1 "C17orf28, DMC1, HID-1" ENSG00000167861 "HID1 domain containing" Q8IV36 17 74950742-74973166 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 111.2" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 71.4;Intestinal goblet cells: 89.5;Paneth cells: 87.8;Proximal enterocytes: 107.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 2.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "MCF7: 115.9;OE19: 99.2;SH-SY5Y: 56.7;SK-BR-3: 172.6;T-47d: 101.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031406 Approved Supported "Golgi apparatus,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 27: Mucus-secreting cells - Mucin production" "Golgi apparatus, Cytosol" "HPA031406: AB_2673866" "unprognostic (7.41e-2)" "unprognostic (1.96e-1)" "unprognostic (2.69e-1)" "unprognostic (2.22e-3)" "unprognostic (4.47e-3)" "unprognostic (6.79e-3)" "unprognostic (4.00e-2)" "unprognostic (1.11e-1)" "unprognostic (2.78e-1)" "unprognostic (3.90e-1)" "unprognostic (1.54e-3)" "unprognostic (1.37e-1)" "prognostic favorable (3.13e-5)" "unprognostic (1.17e-1)" "unprognostic (2.83e-1)" "unprognostic (1.09e-1)" "prognostic favorable (1.34e-4)" 13.2 5.8 21.7 6.6 26.9 2.0 23.2 41.5 33.3 19.9 2.8 17.9 39.1 11.9 29.1 5.5 19.0 21.6 12.4 22.0 24.3 12.3 4.4 20.4 5.3 27.4 22.7 3.0 111.2 14.4 44.0 20.1 30.3 36.2 17.9 8.7 86.2 20.2 4.6 7.6 27.3 6.3 10.4 16.7 68.7 6.8 25.4 2.8 16.8 5.7 6.3 12.3 7.6 39.1 5.2 11.4 1.3 15.8 0.0 0.0 2.7 0.0 0.6 1.1 1.0 10.6 5.8 0.0 1.0 0.0 1.4 4.9 14.5 1.0 0.8 0.0 11.4 0.1 0.3 10.1 2.7 0.0 1.1 0.2 6.0 0.1 2.4 0.3 26.0 3.8 0.7 4.0 0.0 115.9 0.7 0.2 0.4 99.2 7.1 0.2 0.0 21.8 14.5 44.8 21.1 56.7 0.0 172.6 0.0 3.6 101.2 0.0 0.5 0.1 1.4 0.4 0.0 2.0 0.3 0.1 0.2 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.5 0.6 0.9 0.7 0.0 0.1 1.0 1.1 0.0 0.0 0.0 2.6 0.0 0.4 21.7 26.9 41.5 33.3 22.0 24.3 27.4 22.7 30.3 10.4 25.4 39.1 21.4 0.0 5.5 4.9 4.6 1.5 2.6 3.1 0.6 14.3 20.4 12.3 3.8 4.3 8.6 0.0 0.0 26.3 1.1 16.0 3.9 19.0 0.4 10.2 3.0 19.1 35.3 0.0 16.1 26.9 1.7 1.0 71.4 20.3 0.0 1.1 20.7 0.4 2.5 20.2 15.5 89.5 16.2 0.8 0.4 1.0 0.9 0.7 7.2 6.5 0.6 2.8 0.0 8.0 50.9 22.9 87.8 0.0 22.7 17.8 107.4 0.5 6.5 4.4 0.0 1.5 1.8 0.4 2.1 0.5 0.4 35.0 1.8 0.1 15.6 13.9 HINT3 "FLJ33126, HINT4" ENSG00000111911 "Histidine triad nucleotide binding protein 3" Q9NQE9 6 125956770-125980244 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 112.8" "Cell type enhanced" "Detected in all" "Early spermatids: 352.2;Spermatocytes: 110.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027914 Approved Approved Nucleoli,Mitochondria,Cytosol NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 80: Striated muscle - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nucleoli, Mitochondria" Cytosol "HPA027914: AB_10602424" "prognostic unfavorable (4.99e-4)" "unprognostic (4.75e-3)" "unprognostic (3.75e-2)" "unprognostic (1.29e-1)" "unprognostic (1.59e-1)" "unprognostic (1.71e-1)" "unprognostic (1.74e-1)" "unprognostic (4.88e-3)" "unprognostic (3.82e-1)" "unprognostic (1.27e-1)" "unprognostic (2.18e-2)" "unprognostic (1.05e-1)" "prognostic favorable (1.05e-6)" "unprognostic (4.09e-2)" "unprognostic (4.76e-2)" "unprognostic (9.56e-2)" "unprognostic (1.64e-1)" 18.1 23.4 31.2 12.6 33.9 12.3 23.0 31.0 43.3 18.3 22.8 19.6 15.7 16.6 17.8 22.3 16.4 16.2 28.4 29.4 31.4 22.2 28.3 21.0 11.3 33.9 32.1 14.7 19.3 30.6 14.4 14.5 33.8 29.7 17.6 15.3 25.5 22.4 112.8 17.5 16.0 17.3 36.6 10.5 24.8 12.3 32.5 13.6 23.5 84.6 11.4 18.4 10.8 38.0 13.2 10.3 14.1 29.5 5.5 14.8 17.5 14.1 20.2 10.6 11.0 25.6 7.2 28.4 25.5 9.4 23.7 19.5 18.2 11.9 12.3 27.4 23.5 12.0 15.1 21.6 25.4 19.2 19.6 11.8 25.9 10.7 27.0 27.3 16.1 21.0 38.3 18.7 10.6 20.1 15.5 13.7 4.8 27.1 9.9 12.8 9.7 9.7 21.8 24.0 28.2 17.4 12.9 18.0 67.8 10.2 18.4 28.9 11.4 7.2 10.1 34.8 20.3 27.1 33.3 18.2 20.4 18.1 9.5 12.5 9.3 8.9 4.4 5.9 4.6 7.0 5.9 4.8 7.7 6.3 6.0 5.3 11.2 5.9 8.6 4.3 6.3 5.3 31.2 33.9 31.0 43.3 29.4 31.4 33.9 32.1 33.8 36.6 32.5 38.0 11.7 80.1 61.2 11.8 16.7 18.1 10.2 22.1 24.5 21.8 26.5 18.4 38.7 10.0 29.8 16.5 8.4 19.2 13.4 17.2 33.2 29.3 352.2 23.6 11.5 12.3 16.3 6.9 27.0 20.2 6.4 13.7 19.4 25.8 9.5 15.2 10.4 17.5 27.2 6.7 29.8 25.1 20.3 15.3 14.6 78.3 9.9 19.3 21.4 5.6 17.3 43.4 11.3 21.6 40.0 21.4 28.7 17.3 8.1 20.9 15.3 28.0 25.7 25.4 6.6 18.3 15.1 110.7 40.2 21.5 17.3 26.4 11.3 14.6 18.5 19.9 HJV "haemojuvelin, hemojuvelin, HFE2, HFE2A, JH, RGMC" ENSG00000168509 "Hemojuvelin BMP co-receptor" Q6ZVN8 1 146017468-146036746 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "liver: 239.6;skeletal muscle: 591.1;tongue: 291.6" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 96 "liver cancer: 87.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HSkMC: 1.5;K-562: 1.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA 69000 "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 1: K-562 - Erythropoiesis" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (2.30e-1)" "unprognostic (6.98e-4)" "unprognostic (7.06e-2)" "unprognostic (1.11e-2)" "unprognostic (2.77e-3)" "unprognostic (2.55e-1)" "unprognostic (8.50e-2)" "unprognostic (2.36e-1)" "unprognostic (7.14e-2)" "unprognostic (1.18e-1)" "unprognostic (8.96e-8)" "unprognostic (6.61e-2)" "unprognostic (2.72e-1)" "unprognostic (1.76e-2)" 0.1 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 7.9 0.1 0.1 67.5 0.0 0.1 0.2 239.6 0.1 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.1 2.2 0.0 0.0 5.9 0.0 591.1 0.4 0.1 0.2 0.4 0.2 0.1 1.6 0.1 0.3 0.1 291.6 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.2 0.1 0.1 0.4 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 HLA-DOA "HLA-D0-alpha, HLA-DNA, HLA-DZA" ENSG00000204252 "Major histocompatibility complex, class II, DO alpha" P06340 6 33004182-33009591 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 28.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 30.3;B-cells: 61.5;dendritic cells: 20.3;Kupffer cells: 29.4;Langerhans cells: 59.0;Macrophages: 37.7;monocytes: 41.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "myeloid DC: 17.8;naive B-cell: 21.0" "Group enriched" "Detected in many" 11 "B-cells: 21.0;dendritic cells: 17.8;monocytes: 6.0" "Cell line enhanced" "Detected in some" "Daudi: 12.9;HDLM-2: 9.1;REH: 40.5;U-698: 8.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA045038, HPA076922" Enhanced NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 64: Macrophages - Immune response" "Cluster 14: REH - Unknown function" "Cluster 41: Macrophages - Immune response" "HPA045038: AB_10959457, HPA076922: " "unprognostic (8.02e-2)" "unprognostic (2.30e-2)" "unprognostic (2.60e-2)" "unprognostic (1.19e-1)" "unprognostic (3.01e-1)" "unprognostic (3.83e-2)" "unprognostic (2.60e-1)" "unprognostic (9.86e-3)" "unprognostic (1.31e-1)" "unprognostic (1.50e-1)" "unprognostic (3.68e-1)" "unprognostic (4.39e-2)" "unprognostic (1.91e-1)" "unprognostic (9.95e-2)" "unprognostic (3.65e-2)" "unprognostic (8.70e-2)" "unprognostic (5.94e-2)" 7.1 6.1 0.2 7.8 0.4 1.5 6.5 0.4 0.4 4.9 0.3 3.2 5.0 3.0 1.2 2.3 5.0 2.1 2.2 0.3 1.0 8.0 2.8 12.7 15.1 1.8 0.8 2.8 2.4 0.9 3.5 0.0 1.5 5.0 4.2 0.4 3.2 2.1 0.8 2.8 15.2 1.1 0.8 28.7 4.0 0.4 0.7 7.0 4.5 1.0 19.8 3.0 3.7 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 12.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 9.1 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.1 0.0 0.0 0.0 40.5 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.1 1.4 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.8 0.1 8.2 0.0 0.2 0.0 0.0 1.0 0.0 0.0 6.0 0.0 14.6 0.1 0.3 17.8 21.0 0.3 1.3 0.7 0.2 4.7 5.0 1.0 2.4 0.2 0.4 0.4 0.4 0.3 1.0 1.8 0.8 1.5 0.8 0.7 1.2 7.5 3.2 30.3 0.0 61.5 1.9 0.6 0.1 0.6 0.0 0.5 2.4 1.6 1.5 2.0 3.7 0.0 0.1 20.3 0.3 0.0 6.6 0.1 0.3 0.2 8.5 0.0 2.5 0.0 0.2 0.1 1.2 0.5 0.3 5.1 3.5 1.1 0.0 13.4 0.0 0.0 0.1 2.0 29.4 59.0 0.2 0.3 37.7 0.0 6.5 41.9 0.6 4.1 0.0 0.1 0.3 0.0 0.0 0.9 0.6 0.0 2.9 1.4 0.2 0.0 0.7 0.6 0.0 0.2 0.5 1.1 0.1 4.1 1.0 0.3 1.2 HLA-DPA1 HLA-DP1A ENSG00000231389 "Major histocompatibility complex, class II, DP alpha 1" P20036 6 33064569-33080775 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 319.9;lymphoid tissue: 359.6" "Cell type enhanced" "Detected in many" "B-cells: 1387.3;Kupffer cells: 1794.6;Langerhans cells: 8122.8;Macrophages: 2736.9;monocytes: 2940.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 81.8;intermediate monocyte: 187.4;memory B-cell: 150.4;myeloid DC: 296.0;naive B-cell: 136.5;non-classical monocyte: 124.1;plasmacytoid DC: 82.6" "Group enriched" "Detected in all" 7 "B-cells: 150.4;dendritic cells: 296.0;monocytes: 187.4" "Cell line enhanced" "Detected in many" "Daudi: 37.2;HDLM-2: 115.9;REH: 30.3;U-698: 26.1" HPA017967 Enhanced Supported Vesicles NA NA 240000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 64: Macrophages - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 41: Macrophages - Immune response" Vesicles "HPA017967: AB_1853929" "unprognostic (8.93e-3)" "unprognostic (3.15e-2)" "unprognostic (3.64e-2)" "unprognostic (9.40e-3)" "unprognostic (9.07e-2)" "unprognostic (2.80e-2)" "unprognostic (5.69e-2)" "unprognostic (1.82e-2)" "unprognostic (7.28e-2)" "unprognostic (1.39e-1)" "unprognostic (1.93e-1)" "unprognostic (1.80e-1)" "unprognostic (8.38e-2)" "unprognostic (1.17e-1)" "unprognostic (4.69e-2)" "unprognostic (8.11e-2)" "unprognostic (1.06e-1)" 180.8 108.0 2.2 33.4 2.0 12.8 138.4 2.7 3.3 76.7 2.5 72.1 20.2 55.3 8.3 43.1 63.0 13.0 62.0 2.0 3.4 99.0 36.8 319.9 51.3 4.9 2.8 24.9 28.6 5.9 58.0 3.4 4.3 64.0 16.1 2.0 59.5 16.2 29.5 66.3 174.4 14.6 4.3 359.6 52.1 13.4 3.1 30.2 76.6 7.3 51.5 58.6 60.0 4.4 0.1 0.0 0.0 0.0 0.8 1.3 1.1 0.4 0.4 0.5 0.0 0.0 4.9 37.2 5.0 0.9 7.1 0.0 0.0 0.0 0.1 115.9 2.5 6.2 0.0 0.0 0.1 0.0 11.6 1.7 0.0 2.2 0.0 0.0 0.6 0.0 0.0 3.3 0.0 0.0 0.1 0.1 0.6 0.0 0.0 30.3 0.0 4.9 0.1 0.0 0.1 0.0 0.0 0.0 2.9 0.0 0.0 1.3 2.6 7.8 0.1 0.1 0.0 5.6 0.9 26.1 12.2 0.2 4.4 2.2 81.8 6.6 21.6 187.4 5.7 150.4 9.6 23.9 296.0 136.5 3.4 15.7 3.0 20.9 124.1 82.6 29.2 136.0 2.2 2.0 2.7 3.3 2.0 3.4 4.9 2.8 4.3 4.3 3.1 4.4 621.8 83.3 404.3 0.3 1387.3 206.7 7.2 12.4 9.1 2.8 41.2 110.4 12.1 64.3 107.3 23.9 0.0 4.2 574.9 10.6 9.8 36.4 2.8 1.2 4.1 337.8 10.2 80.3 0.5 18.8 9.3 53.7 48.4 2.8 64.6 14.3 62.2 7.5 1153.8 5.0 0.9 18.2 12.2 1794.6 8122.8 11.7 18.0 2736.9 302.4 32.8 2940.3 5.1 94.7 0.0 0.1 4.7 5.4 27.4 100.2 10.6 114.0 42.7 129.2 5.0 52.6 14.7 29.8 1.3 4.8 6.0 175.2 6.8 157.8 11.5 28.6 34.4 HLA-DPB1 HLA-DP1B ENSG00000223865 "Major histocompatibility complex, class II, DP beta 1" P04440 6 33075990-33089696 "Human disease related genes, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 278.7;lymphoid tissue: 409.4" "Cell type enhanced" "Detected in many" "B-cells: 1569.6;Kupffer cells: 2374.2;Langerhans cells: 12627.8;Macrophages: 2453.8;monocytes: 3754.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "myeloid DC: 285.5" "Group enriched" "Detected in all" 10 "B-cells: 227.8;dendritic cells: 285.5;monocytes: 137.5" "Group enriched" "Detected in some" 6 "HDLM-2: 65.9;REH: 26.5" "HPA011078, HPA058509" Enhanced Approved "Nucleoplasm,Cell Junctions" NA NA 470000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 64: Macrophages - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 41: Macrophages - Immune response" "Cell Junctions" Nucleoplasm "HPA011078: AB_1079378, HPA058509: AB_2683737" "unprognostic (5.44e-3)" "unprognostic (7.03e-3)" "unprognostic (9.84e-2)" "prognostic favorable (3.38e-4)" "unprognostic (9.43e-2)" "unprognostic (1.80e-2)" "unprognostic (1.52e-1)" "unprognostic (1.51e-3)" "unprognostic (1.77e-2)" "unprognostic (5.64e-2)" "unprognostic (1.57e-1)" "unprognostic (4.34e-1)" "unprognostic (4.35e-2)" "unprognostic (1.80e-1)" "unprognostic (4.17e-2)" "unprognostic (3.58e-2)" "unprognostic (1.85e-1)" 151.6 101.3 1.0 42.0 1.0 5.8 112.8 3.3 1.3 68.2 0.9 69.4 12.4 50.2 2.9 43.9 55.7 17.2 51.1 0.8 1.8 96.1 38.6 278.7 66.7 1.8 1.3 26.2 32.4 1.0 51.5 0.8 1.8 70.3 2.5 1.5 57.2 6.4 25.1 72.3 176.5 4.7 2.1 409.4 54.1 12.8 1.0 10.9 69.5 1.3 42.2 49.2 56.5 3.0 0.0 0.0 0.1 0.0 0.0 0.3 3.6 0.0 0.0 0.0 0.0 0.0 0.0 1.3 6.2 0.2 0.0 0.1 0.0 0.0 0.0 65.9 1.9 1.5 0.0 0.0 0.0 0.0 0.5 1.4 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 4.9 0.0 0.0 26.5 0.1 0.3 0.3 0.0 0.9 0.0 0.0 0.3 0.1 0.4 0.0 0.1 1.8 0.1 0.2 0.0 0.0 7.2 0.3 4.4 1.1 0.0 0.0 0.5 59.6 4.0 14.8 137.5 1.8 226.6 5.1 22.2 285.5 227.8 2.3 11.9 1.6 8.2 60.3 77.5 22.7 107.8 1.0 1.0 3.3 1.3 0.8 1.8 1.8 1.3 1.8 2.1 1.0 3.0 354.8 67.3 330.7 1.3 1569.6 300.5 26.0 5.6 19.4 26.9 54.0 123.6 10.3 67.2 62.3 29.5 16.7 4.8 692.9 7.8 3.9 58.3 3.6 2.0 16.3 297.8 9.6 87.9 1.3 15.6 8.1 62.3 48.4 2.7 61.6 13.6 97.1 8.8 1099.4 8.4 1.6 13.0 10.2 2374.2 12627.8 10.1 27.4 2453.8 323.7 20.6 3754.7 43.3 203.9 2.5 0.2 7.4 10.0 21.1 50.9 28.2 154.7 60.2 54.4 21.9 46.0 21.4 47.5 1.3 7.8 6.4 233.3 9.0 200.7 3.9 23.0 51.7 HLA-DRA HLA-DRA1 ENSG00000204287 "Major histocompatibility complex, class II, DR alpha" P01903 6 32439878-32445046 "Plasma proteins, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 940.2;lymphoid tissue: 1277.8" "Cell type enhanced" "Detected in many" "B-cells: 4744.7;Kupffer cells: 4311.3;Langerhans cells: 24286.4;Macrophages: 6377.4;monocytes: 6924.4;Proximal enterocytes: 3639.5" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebral cortex: 36.2" "Group enriched" "Detected in all" 4 "classical monocyte: 209.3;intermediate monocyte: 408.8;memory B-cell: 379.6;naive B-cell: 418.5;non-classical monocyte: 255.2;plasmacytoid DC: 229.8" "Group enriched" "Detected in all" 5 "B-cells: 418.5;dendritic cells: 229.8;monocytes: 408.8" "Cell line enhanced" "Detected in some" "Daudi: 715.7;HDLM-2: 1623.6;REH: 277.1;U-266/70: 242.2;U-698: 730.2;U-87 MG: 258.0" "Low region specificity" "Detected in all" "CAB002798, CAB015402, HPA050162, HPA053176" Enhanced NA NA 950000 "Cluster 49: Eosinophils - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 41: Macrophages - Immune response" "CAB002798: , CAB015402: AB_629980, HPA050162: AB_2681037, HPA053176: AB_2682070" "unprognostic (1.20e-3)" "unprognostic (4.70e-3)" "prognostic favorable (5.30e-4)" "unprognostic (3.13e-3)" "unprognostic (1.30e-1)" "unprognostic (2.72e-2)" "unprognostic (1.33e-1)" "unprognostic (1.11e-2)" "unprognostic (2.77e-2)" "unprognostic (3.05e-2)" "unprognostic (3.92e-2)" "unprognostic (1.89e-1)" "unprognostic (1.35e-1)" "unprognostic (1.98e-1)" "unprognostic (4.42e-2)" "unprognostic (5.67e-2)" "unprognostic (2.52e-2)" 510.2 294.8 3.3 304.4 3.6 1.0 370.7 3.6 36.2 176.5 3.6 175.6 117.9 124.0 260.4 129.1 145.1 61.5 128.4 3.6 3.6 290.3 95.8 940.2 1277.8 7.8 7.5 58.5 73.9 0.1 125.6 23.5 5.9 141.5 151.1 8.3 156.0 8.5 79.4 195.5 713.3 1.4 3.5 1091.9 388.0 25.6 4.0 198.8 175.5 0.0 805.5 172.8 143.3 6.0 0.8 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.5 715.7 6.3 0.0 0.0 1.5 0.0 0.0 0.0 1623.6 0.0 17.7 0.0 0.0 0.0 1.1 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 3.1 0.1 0.0 0.0 277.1 0.4 0.9 0.0 0.1 0.6 0.7 1.3 0.3 22.8 0.0 0.0 0.8 0.0 8.9 1.4 2.7 1.6 242.2 6.1 730.2 258.0 0.5 0.5 5.9 209.3 74.1 2.1 408.8 1.1 379.6 2.4 10.8 4.6 418.5 1.2 2.2 17.9 15.0 255.2 229.8 19.8 137.8 3.3 3.6 3.6 36.2 3.6 3.6 7.8 7.5 5.9 3.5 4.0 6.0 935.5 291.7 1070.1 0.3 4744.7 748.4 18.1 160.7 84.2 4.1 101.2 172.6 22.5 115.8 458.0 150.8 0.0 12.7 983.5 79.5 29.4 329.2 8.7 26.9 5.2 803.1 64.9 228.5 0.2 59.8 18.3 128.0 159.6 27.1 174.8 80.9 167.4 19.8 2809.0 1.7 0.2 175.0 146.5 4311.3 24286.4 25.8 30.1 6377.4 773.7 59.0 6924.4 8.4 81.4 0.0 0.1 46.3 182.5 4.5 107.5 32.9 3639.5 303.5 487.1 19.7 72.3 27.8 78.0 3.5 5.2 35.3 576.1 25.9 218.8 0.8 245.4 273.3 HLA-E ENSG00000204592 "Major histocompatibility complex, class I, E" P13747 6 30489509-30494194 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 2347.3;Hepatic stellate cells: 1647.8;NK-cells: 1874.4" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebral cortex: 109.5" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 212.3;U-266/70: 284.8" "CAB024589, HPA031454" Enhanced Approved Vesicles "Secreted to blood" NA NA 100000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "CAB024589: AB_324025, HPA031454: AB_2673891" "unprognostic (1.14e-2)" "unprognostic (1.38e-2)" "unprognostic (9.20e-2)" "unprognostic (2.47e-3)" "unprognostic (2.06e-1)" "unprognostic (3.63e-1)" "unprognostic (1.14e-2)" "unprognostic (1.33e-1)" "unprognostic (1.75e-2)" "unprognostic (1.35e-2)" "unprognostic (5.57e-2)" "unprognostic (2.04e-2)" "prognostic unfavorable (3.86e-4)" "unprognostic (2.90e-1)" "unprognostic (4.14e-2)" "unprognostic (1.75e-3)" "unprognostic (1.42e-3)" 724.7 217.2 9.6 173.7 10.0 410.3 578.9 10.9 109.5 360.1 7.3 329.4 0.6 313.5 119.3 330.9 336.5 186.1 356.0 7.7 13.1 375.2 332.8 1144.6 336.3 16.6 22.7 213.2 156.6 95.8 121.8 117.3 16.1 251.2 116.8 12.4 252.5 93.0 179.2 518.3 428.9 89.0 10.0 1007.2 259.5 41.1 11.7 86.0 381.9 0.0 137.5 295.0 366.3 14.2 100.7 16.7 6.8 57.0 212.3 166.4 0.9 0.0 0.0 0.1 0.3 40.0 189.1 65.6 98.7 92.7 148.3 121.6 12.8 53.1 0.0 67.6 32.7 78.6 18.7 0.0 0.0 0.2 38.3 135.4 94.4 67.7 0.0 0.0 0.2 34.6 9.8 0.9 54.5 0.2 0.3 0.8 0.5 32.0 0.0 20.6 0.2 97.4 82.7 58.4 0.3 4.8 63.3 56.9 0.3 1.2 0.0 132.7 102.0 60.7 0.1 0.5 14.7 284.8 171.6 29.4 0.3 62.1 149.2 1140.0 335.4 1153.0 723.3 550.2 602.2 449.1 539.9 709.2 158.5 450.3 531.5 547.8 1916.1 512.9 648.0 138.3 611.7 1441.6 9.6 10.0 10.9 109.5 7.7 13.1 16.6 22.7 16.1 10.0 11.7 14.2 2347.3 310.9 411.0 8.1 950.6 484.6 386.6 284.2 183.8 2.7 238.7 204.0 108.3 231.6 270.0 123.2 6.2 88.2 1304.6 603.0 17.6 484.9 5.0 157.7 157.9 1554.7 216.2 172.3 0.1 677.2 277.0 402.8 233.4 325.6 531.6 59.2 1647.8 120.1 700.6 5.0 0.1 545.3 248.2 1220.4 512.2 11.0 132.0 821.6 466.0 105.9 740.5 100.2 1874.4 2.0 0.5 682.2 559.1 76.3 716.6 436.9 473.9 79.9 214.7 9.5 177.5 535.1 350.1 10.6 7.0 170.0 426.5 359.0 1162.1 196.5 285.0 544.4 HMGB2 HMG2 ENSG00000164104 "High mobility group box 2" P26583 4 173331376-173334432 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Chemotaxis, DNA recombination, Immunity, Inflammatory response, Innate immunity, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 12 "bone marrow: 2347.2;lymphoid tissue: 939.2" "Cell type enhanced" "Detected in all" "Erythroid cells: 1915.4;Extravillous trophoblasts: 872.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 798.0" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MOLT-4: 2454.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003506, CAB037206, HPA053314, HPA073663" Enhanced Supported Nucleoplasm,Nucleoli "Secreted to blood" NA Yes 1200000 "Cluster 46: Basophils - DNA binding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Nucleoli "CAB037206: AB_1079071, HPA003506: AB_1079070, HPA053314: AB_2682109, HPA073663: " "unprognostic (2.82e-1)" "unprognostic (8.52e-3)" "unprognostic (2.56e-1)" "unprognostic (8.37e-2)" "unprognostic (8.05e-2)" "unprognostic (1.21e-2)" "prognostic unfavorable (3.76e-5)" "unprognostic (2.12e-1)" "prognostic unfavorable (3.13e-4)" "unprognostic (4.41e-2)" "prognostic unfavorable (7.04e-4)" "unprognostic (9.65e-2)" "prognostic unfavorable (7.60e-12)" "unprognostic (1.60e-2)" "unprognostic (2.83e-2)" "unprognostic (2.68e-2)" "unprognostic (1.21e-2)" 90.3 31.0 36.3 146.1 38.4 2347.2 89.1 35.4 49.9 79.0 33.0 117.1 93.2 92.3 47.3 115.6 78.8 43.5 85.8 33.2 38.3 74.3 37.8 83.8 390.4 37.5 36.8 118.9 27.2 18.3 35.4 111.0 38.0 46.9 122.2 134.1 59.8 35.2 72.4 75.1 108.7 65.5 36.3 159.5 66.0 136.0 36.1 939.2 56.4 57.0 388.9 68.2 86.1 40.1 498.2 114.6 976.8 444.4 118.2 118.2 375.1 366.3 271.3 386.7 345.7 329.0 673.6 1645.5 79.2 203.0 207.4 190.3 645.0 196.1 601.0 1004.0 303.4 1823.2 308.8 487.8 115.7 1642.8 683.4 114.7 59.2 194.2 439.1 211.5 402.8 866.1 703.9 2282.4 358.9 409.9 2454.9 1513.7 355.4 289.4 199.3 1226.7 499.7 620.4 227.0 208.8 838.6 759.0 365.5 209.6 166.6 340.8 291.1 1173.2 236.0 175.5 513.6 219.0 554.9 734.8 437.1 1869.4 149.1 1178.4 464.4 798.0 135.9 407.0 94.1 57.6 86.2 72.5 137.8 131.1 112.8 57.6 88.4 85.3 316.7 83.0 49.1 43.2 266.4 107.6 36.3 38.4 35.4 49.9 33.2 38.3 37.5 36.8 38.0 36.3 36.1 40.1 167.0 28.9 64.1 5.9 153.2 158.8 141.5 131.8 75.1 48.9 75.3 107.8 229.0 38.6 78.3 55.2 35.5 472.6 222.9 116.5 142.8 25.9 30.4 71.2 71.7 128.0 74.7 1915.4 2.7 16.1 872.5 121.5 63.2 76.5 110.6 210.5 171.7 26.5 210.1 45.4 4.7 191.2 109.9 295.0 142.9 33.1 105.3 233.9 67.6 6.5 241.9 81.8 132.8 1.0 4.8 11.3 75.2 57.6 268.6 114.2 65.4 51.0 149.8 143.5 78.9 71.7 134.4 493.6 400.9 233.6 134.0 128.7 289.5 42.3 284.7 89.0 HMGB4 FLJ40388 ENSG00000176256 "High mobility group box 4" Q8WW32 1 33860475-33864791 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1077 "testis: 372.2" "Group enriched" "Detected in some" 117 "Early spermatids: 11656.4;Late spermatids: 21015.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA035699 Enhanced NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 34: Spermatids - Unknown function" "HPA035699: AB_10960531" "unprognostic (1.33e-1)" 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 372.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.3 0.1 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11656.4 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21015.5 100.0 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 71.8 0.0 0.0 0.0 0.0 0.0 0.0 46.0 0.0 0.0 138.7 65.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 HMGCL HL ENSG00000117305 "3-hydroxy-3-methylglutaryl-CoA lyase" P35914 1 23801885-23838620 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Lyase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 322.5" "Cell type enhanced" "Detected in all" "Hepatocytes: 172.4;Proximal tubular cells: 216.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004727 Enhanced "Intracellular and membrane" NA NA 34000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA004727: AB_1079074" "unprognostic (8.24e-2)" "unprognostic (3.21e-2)" "prognostic favorable (7.67e-4)" "unprognostic (1.23e-3)" "unprognostic (5.47e-3)" "unprognostic (1.26e-1)" "unprognostic (2.04e-1)" "unprognostic (3.85e-2)" "unprognostic (1.08e-1)" "unprognostic (2.24e-1)" "unprognostic (3.05e-1)" "unprognostic (8.24e-2)" "prognostic favorable (5.07e-8)" "unprognostic (1.72e-1)" "unprognostic (2.46e-2)" "unprognostic (8.60e-2)" "unprognostic (3.39e-3)" 27.5 63.0 26.3 16.8 27.5 7.5 25.8 27.5 28.3 27.5 33.0 53.3 45.7 20.2 47.2 32.8 35.6 26.3 42.5 24.6 26.9 115.5 322.5 23.6 21.7 28.0 26.2 21.6 33.4 60.2 26.3 19.9 27.7 31.7 52.9 16.1 30.3 27.9 63.7 25.5 40.0 23.3 27.4 26.8 40.9 17.9 30.1 23.4 40.5 70.2 25.1 28.6 24.2 29.6 28.5 16.0 17.7 13.4 70.6 53.5 6.8 22.0 38.3 23.3 28.2 10.2 53.7 14.8 44.3 34.6 19.0 22.4 21.3 35.7 25.2 30.4 16.1 19.8 13.8 23.5 90.9 7.8 12.7 62.4 52.0 30.8 58.5 62.5 32.2 27.4 20.6 20.3 43.3 29.3 12.2 15.3 4.6 77.4 22.1 17.2 14.5 27.9 55.4 14.5 14.8 13.2 28.6 10.8 49.3 23.3 33.9 19.3 24.3 19.3 11.6 35.5 9.7 28.7 15.2 13.3 47.7 28.7 23.0 103.5 67.0 66.0 36.3 66.0 39.8 45.9 39.1 42.1 58.0 51.2 39.6 37.7 25.5 54.4 77.5 43.9 45.5 61.7 26.3 27.5 27.5 28.3 24.6 26.9 28.0 26.2 27.7 27.4 30.1 29.6 19.9 12.8 25.7 14.0 16.3 5.9 29.9 54.3 9.6 24.6 19.9 17.1 33.7 41.5 30.6 49.7 18.8 43.0 10.0 48.1 119.3 57.7 2.3 25.0 17.5 22.5 9.0 18.7 4.3 24.0 27.3 20.8 30.5 23.1 17.7 29.7 30.4 172.4 61.6 35.3 5.3 49.5 28.5 23.5 7.7 3.6 21.8 23.5 21.4 8.4 41.4 37.1 24.7 6.0 12.5 31.2 53.8 24.5 8.3 29.4 70.9 216.8 31.5 25.5 6.6 17.1 21.6 6.6 5.4 13.8 6.5 41.3 15.2 65.6 48.9 24.3 HMOX2 HO-2 ENSG00000103415 "Heme oxygenase 2" P30519 16 4474690-4510347 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Early spermatids: 515.3;Late spermatids: 2001.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025464, HPA040611" Supported Approved Vesicles,Cytosol NA NA 12000 "Cluster 20: T-cells - T-cell receptor" "Cluster 43: Testis - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 31: Spermatids - Spermatogenesis" "Vesicles, Cytosol" "CAB025464: , HPA040611: AB_10961034" "unprognostic (3.33e-1)" "unprognostic (3.58e-2)" "unprognostic (1.11e-1)" "prognostic favorable (7.91e-4)" "unprognostic (2.74e-1)" "unprognostic (4.27e-2)" "unprognostic (6.23e-2)" "unprognostic (5.77e-2)" "unprognostic (1.43e-2)" "unprognostic (3.60e-1)" "unprognostic (7.74e-3)" "unprognostic (9.87e-2)" "prognostic favorable (8.98e-6)" "unprognostic (3.51e-2)" "unprognostic (4.14e-2)" "unprognostic (1.65e-2)" "unprognostic (2.64e-1)" 63.0 51.3 43.7 23.2 51.9 18.3 55.7 56.9 55.2 47.1 36.2 41.0 34.8 35.8 22.5 84.5 35.9 26.9 149.9 47.7 50.0 71.2 109.5 46.6 33.2 55.8 49.2 25.6 39.7 38.6 43.8 17.9 57.1 34.5 25.1 22.5 44.1 14.1 37.9 44.4 42.6 22.7 44.7 67.8 100.2 152.2 54.3 24.3 41.9 32.3 36.3 33.2 49.0 53.5 82.9 38.2 20.5 45.6 65.8 31.5 33.8 53.9 26.5 48.3 43.7 48.3 55.5 36.9 64.0 55.7 34.6 51.5 75.4 126.9 48.4 51.5 48.4 27.5 35.2 63.3 43.7 56.8 44.4 48.7 41.7 55.7 37.6 37.9 83.7 46.9 44.7 18.1 44.5 114.3 48.7 58.4 34.2 81.1 35.7 54.3 33.7 84.4 72.3 51.8 34.4 19.4 43.1 95.1 66.4 33.9 58.2 36.3 91.7 25.7 39.9 120.3 30.1 24.3 30.0 78.0 16.5 52.5 35.2 87.6 37.1 252.6 166.3 46.5 142.1 69.8 153.8 168.5 73.6 66.8 145.5 151.6 125.1 99.0 35.7 39.2 155.4 142.3 43.7 51.9 56.9 55.2 47.7 50.0 55.8 49.2 57.1 44.7 54.3 53.5 33.8 35.3 41.5 7.8 37.2 54.8 35.7 73.5 19.4 29.3 26.4 29.1 70.6 32.9 54.5 36.8 20.9 75.3 59.8 70.7 129.1 79.7 515.3 38.6 30.9 53.4 31.8 14.3 23.0 90.7 69.6 39.4 89.7 53.3 19.7 38.8 75.0 93.0 67.2 28.6 21.6 37.6 85.5 23.9 52.9 2001.6 45.4 30.6 62.2 5.6 29.3 53.9 141.1 9.5 32.9 114.9 70.7 56.1 47.1 37.7 110.8 239.3 39.9 27.8 72.3 14.6 58.0 199.7 149.8 28.2 51.6 38.4 88.3 47.4 48.9 28.7 HOMER1 "HOMER-1B, SYN47, Ves-1" ENSG00000152413 "Homer scaffold protein 1" Q86YM7 5 79372636-79514134 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.6;skeletal muscle: 34.0" "Cell type enhanced" "Detected in many" "Excitatory neurons: 440.0;Inhibitory neurons: 112.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004437, HPA036521, HPA036522" Enhanced Supported Approved Cytosol No No "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 47: Non-specific - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "CAB004437: AB_627742, HPA036521: AB_2675170, HPA036522: AB_2675171" "unprognostic (2.80e-1)" "unprognostic (5.30e-2)" "unprognostic (4.00e-2)" "unprognostic (5.79e-2)" "unprognostic (8.83e-2)" "unprognostic (6.40e-2)" "unprognostic (2.00e-3)" "unprognostic (2.41e-3)" "unprognostic (2.22e-1)" "unprognostic (3.79e-1)" "unprognostic (3.07e-3)" "unprognostic (3.98e-1)" "unprognostic (7.35e-2)" "unprognostic (9.30e-2)" "unprognostic (1.72e-1)" "unprognostic (2.83e-2)" "unprognostic (2.86e-3)" 2.8 1.3 2.1 2.3 14.0 0.3 2.5 10.6 27.6 3.9 0.0 1.2 0.7 6.7 4.1 4.6 1.7 6.8 20.5 17.9 5.6 5.8 1.7 5.1 1.1 0.0 3.3 3.8 2.2 4.1 2.3 5.4 2.2 1.7 1.0 5.8 1.2 1.7 34.0 2.4 0.8 4.7 0.6 0.8 2.0 5.3 7.4 1.3 15.0 12.9 1.4 8.0 1.7 15.1 14.6 9.8 14.5 23.1 5.4 3.6 33.5 9.0 7.2 9.0 9.6 15.5 9.9 0.2 26.9 7.8 16.2 7.7 18.2 24.5 15.4 2.2 14.3 17.3 3.9 15.7 8.8 8.3 5.4 5.8 15.4 8.1 22.4 3.6 4.3 26.4 21.7 9.3 11.7 20.4 34.8 5.7 24.5 5.2 8.4 22.4 23.8 22.2 9.6 22.3 14.7 8.8 17.2 12.0 9.3 16.0 16.5 7.2 0.7 6.6 16.7 8.0 16.1 4.5 10.8 8.5 18.8 3.3 13.0 0.0 0.0 0.0 0.4 0.0 0.2 0.4 0.1 0.1 0.0 0.3 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.1 2.1 14.0 10.6 27.6 17.9 5.6 0.0 3.3 2.2 0.6 7.4 15.1 4.3 51.3 9.6 21.9 12.1 64.2 28.0 8.5 20.5 24.4 25.6 18.2 95.2 7.2 12.1 16.5 27.1 58.4 20.3 4.3 11.7 4.8 4.7 30.6 24.9 9.5 11.4 0.4 440.0 4.3 44.8 19.3 5.6 39.9 5.7 16.9 4.6 6.9 11.9 52.2 112.1 7.5 10.2 9.6 29.7 5.5 5.6 13.9 21.4 31.9 3.0 4.4 8.2 86.0 19.3 5.5 2.7 8.6 8.9 23.3 3.1 7.0 10.8 8.1 13.1 29.7 19.3 6.9 10.3 23.9 54.8 84.4 9.8 10.2 3.0 25.2 HOPX "HOP, LAGY, NECC1, OB1, SMAP31" ENSG00000171476 "HOP homeobox" Q9BPY8 4 56647988-56681899 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, Repressor" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 716.7;skin 1: 1439.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 750.0;Alveolar cells type 2: 569.2;Basal keratinocytes: 414.6;dendritic cells: 345.3;NK-cells: 1150.4;Suprabasal keratinocytes: 377.2;Syncytiotrophoblasts: 321.8" "Cancer enhanced" "Detected in many" "glioma: 43.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "gdT-cell: 518.2;NK-cell: 781.6" "Group enriched" "Detected in all" 15 "NK-cells: 781.6;T-cells: 518.2" "Cell line enhanced" "Detected in many" "HDLM-2: 31.2;HUVEC TERT2: 66.9;RT4: 50.5;TIME: 76.2;U-266/70: 26.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018632, HPA030180" Enhanced Approved "Nuclear bodies,Cytosol" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" "Nuclear bodies" Cytosol "CAB018632: AB_2120833, HPA030180: AB_10603770" "unprognostic (2.32e-1)" "unprognostic (1.81e-2)" "unprognostic (8.03e-3)" "unprognostic (1.97e-1)" "unprognostic (1.45e-1)" "unprognostic (1.78e-2)" "unprognostic (2.88e-1)" "unprognostic (7.79e-2)" "unprognostic (1.02e-1)" "unprognostic (1.03e-1)" "unprognostic (1.71e-1)" "unprognostic (1.26e-1)" "unprognostic (9.30e-5)" "unprognostic (3.40e-2)" "unprognostic (1.51e-1)" "unprognostic (7.10e-2)" "unprognostic (5.33e-2)" 9.5 33.7 212.8 27.7 235.6 12.1 112.2 215.4 322.0 250.1 239.2 30.5 17.2 19.1 541.4 716.7 10.5 35.1 48.8 237.4 212.0 24.0 2.9 372.8 18.4 237.6 211.6 9.4 5.3 13.3 11.7 59.6 218.5 26.9 7.0 22.1 172.0 64.7 19.2 1439.9 11.3 115.6 238.8 11.9 33.9 45.3 215.0 15.8 224.5 31.8 190.4 34.1 368.6 234.2 0.0 0.0 0.0 0.0 5.0 15.7 5.9 0.0 0.0 1.4 1.0 0.0 0.0 12.6 0.7 0.3 2.3 2.2 1.4 0.0 1.9 31.2 0.2 0.1 0.0 0.0 2.0 0.0 0.1 2.6 11.9 3.6 0.0 3.4 66.9 0.0 0.0 0.5 3.2 0.5 0.1 1.0 0.1 3.6 0.0 0.0 0.0 0.3 0.0 50.5 1.0 0.6 0.0 0.0 0.0 4.6 0.0 0.0 76.2 0.0 0.2 0.5 0.1 26.0 0.1 0.1 3.2 0.0 0.0 5.7 1.1 2.0 518.2 3.5 282.0 43.4 123.6 227.6 2.6 36.5 20.9 150.8 11.2 781.6 4.5 3.6 9.1 365.6 212.8 235.6 215.4 322.0 237.4 212.0 237.6 211.6 218.5 238.8 215.0 234.2 14.5 750.0 569.2 38.2 23.3 414.6 42.2 8.7 59.7 3.5 3.4 3.0 14.8 2.8 125.6 1.8 0.0 2.3 345.3 0.8 1.9 0.4 33.3 2.8 4.0 28.7 8.4 30.5 62.2 0.2 5.5 16.7 5.6 5.2 10.1 99.5 5.3 1.2 4.0 0.0 7.9 11.1 4.1 11.4 30.9 45.9 3.1 7.9 35.6 14.0 41.4 166.4 1150.4 7.1 6.7 1.7 0.0 3.0 9.6 31.3 1.2 0.6 12.5 5.6 32.9 3.7 104.8 3.3 15.3 31.6 377.2 321.8 219.9 0.1 1.4 28.8 HOXA11 "HOX1, HOX1I" ENSG00000005073 "Homeobox A11" P31270 7 27181157-27185232 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 44.8;endometrium 1: 96.7;smooth muscle: 41.2" "Cell type enriched" "Detected in some" 19 "Endometrial stromal cells: 116.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 32.5;HEK 293: 44.0;THP-1: 34.7;U-937: 43.4" "Not detected" "Not detected" "Region enriched" "Detected in single" 36 "spinal cord: 3.5" "HPA006770, HPA035623" Enhanced Supported Nucleoplasm NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 32: U-937 - Innate immune response" "Cluster 36: Stromal cells - Cell proliferation" Nucleoplasm "HPA006770: AB_2667672, HPA035623: AB_10601576" "unprognostic (5.95e-2)" "unprognostic (9.23e-2)" "unprognostic (3.07e-2)" "unprognostic (2.70e-2)" "unprognostic (6.29e-2)" "unprognostic (9.78e-2)" "unprognostic (2.82e-3)" "unprognostic (4.36e-2)" "unprognostic (1.61e-2)" "unprognostic (3.05e-2)" "unprognostic (2.08e-3)" "unprognostic (1.73e-2)" "prognostic unfavorable (2.57e-5)" "unprognostic (2.17e-2)" "unprognostic (6.90e-2)" "unprognostic (2.03e-2)" "unprognostic (2.56e-1)" 3.5 0.7 0.0 1.4 0.0 0.0 0.4 0.0 0.0 44.8 0.0 23.1 0.0 96.7 0.0 0.0 1.3 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.0 10.0 0.0 14.7 3.9 0.0 0.1 9.6 7.9 1.5 0.2 41.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 17.0 10.4 0.0 4.8 0.3 0.0 13.1 15.2 11.1 0.0 26.8 32.5 18.9 13.8 0.3 1.7 0.0 6.1 23.5 0.1 3.2 16.3 0.0 14.7 1.6 44.0 5.7 11.2 0.7 0.9 12.5 1.7 6.5 0.6 0.1 0.0 0.0 14.1 1.1 0.4 0.0 2.2 0.4 0.0 9.4 0.0 4.4 13.1 0.7 0.0 0.3 9.6 8.1 5.6 0.0 6.7 0.0 2.0 3.6 1.2 34.7 0.0 0.2 12.9 3.2 1.5 0.0 0.0 0.0 0.2 43.4 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 2.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 1.8 0.0 0.1 0.3 1.1 5.9 0.0 0.8 4.0 116.8 1.3 5.3 0.0 0.0 0.0 0.1 3.6 0.0 1.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 2.1 0.0 0.0 0.3 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 2.8 0.2 0.2 0.0 0.0 0.0 0.9 5.8 1.2 0.1 0.0 0.0 0.0 0.6 0.1 1.1 1.3 HPD "4-HPPD, 4HPPD, GLOD3, PPD" ENSG00000158104 "4-hydroxyphenylpyruvate dioxygenase" P32754 12 121839527-121863596 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Phenylalanine catabolism, Tyrosine catabolism" "Dioxygenase, Oxidoreductase" "Disease variant, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 2530.4" "Group enriched" "Detected in some" 9 "Hepatocytes: 1373.6;Proximal tubular cells: 2144.0" "Cancer enriched" "Detected in many" 100 "liver cancer: 540.9" "Region enhanced" "Detected in many" "hippocampal formation: 7.8" "Immune cell enhanced" "Detected in some" "eosinophil: 7.8" "Group enriched" "Detected in many" 4 "dendritic cells: 3.8;granulocytes: 7.8" "Cell line enriched" "Detected in some" 31 "Hep G2: 516.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA038321, HPA038322" Enhanced Uncertain "Nuclear speckles" NA NA 26000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nuclear speckles" "HPA038321: AB_2675957, HPA038322: AB_10670778" "unprognostic (3.01e-2)" "unprognostic (2.30e-1)" "unprognostic (4.81e-3)" "unprognostic (1.42e-3)" "unprognostic (1.10e-2)" "unprognostic (9.08e-2)" "unprognostic (1.13e-2)" "unprognostic (8.84e-2)" "unprognostic (5.58e-2)" "unprognostic (6.14e-3)" "unprognostic (9.72e-3)" "unprognostic (8.61e-3)" "unprognostic (7.16e-2)" "unprognostic (1.97e-1)" "unprognostic (4.12e-1)" "unprognostic (3.06e-2)" "unprognostic (2.34e-1)" 2.3 5.3 0.6 0.7 0.4 0.9 4.6 3.2 0.6 2.0 119.0 1.2 0.1 4.1 0.7 0.7 6.4 1.1 3.5 7.8 0.5 531.0 2530.4 2.0 0.3 1.5 1.0 4.7 3.9 0.1 1.1 0.3 0.8 2.3 0.5 0.3 0.2 7.3 2.2 0.2 0.9 1.4 0.6 2.3 1.9 10.2 3.5 0.1 0.7 0.1 0.1 3.7 1.9 1.0 0.3 0.9 0.6 0.6 0.3 0.6 0.6 0.0 0.1 0.0 0.0 0.2 0.5 0.2 0.6 1.1 0.2 0.4 0.2 0.0 0.0 0.3 0.8 1.2 5.4 516.4 11.5 1.8 16.4 3.6 0.3 0.0 0.0 1.3 0.0 0.5 0.8 0.0 1.3 1.3 0.2 0.4 9.9 0.4 0.0 0.3 1.6 0.5 0.0 1.4 0.1 0.1 1.5 0.1 0.1 6.9 1.1 0.9 0.2 0.0 0.3 0.1 0.1 0.8 0.6 0.7 0.2 1.2 0.0 0.0 0.6 7.8 0.0 0.8 0.0 0.1 0.1 0.1 1.0 0.1 0.2 0.2 3.9 0.0 1.3 3.8 0.0 0.3 0.6 0.4 3.2 0.6 7.8 0.5 1.5 1.0 0.8 0.6 3.5 1.0 0.0 0.0 0.0 0.7 15.8 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.3 55.8 0.0 92.0 0.0 0.8 0.0 0.0 193.7 0.5 38.0 0.1 0.0 2.6 0.0 80.2 1.0 16.2 0.3 0.4 0.0 0.1 0.0 0.0 38.9 1373.6 0.3 0.0 1.0 0.0 0.0 37.8 0.3 121.0 2.5 10.8 0.0 0.0 0.4 0.0 0.0 1.5 0.7 0.2 0.0 5.3 0.0 0.0 0.0 2144.0 0.0 0.0 0.0 2.0 0.2 1.8 1.4 0.0 0.0 1.1 8.0 7.1 0.0 0.0 HPRT1 "HGPRT, HPRT" ENSG00000165704 "Hypoxanthine phosphoribosyltransferase 1" P00492 X 134460165-134520513 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Purine salvage" "Glycosyltransferase, Transferase" "Disease variant, FDA approved drug targets, Gout" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 226.9;Spermatocytes: 213.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006360, CAB012200" Enhanced Supported Cytosol NA NA 9400000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 58: Brain - Synaptic function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Cytosol "CAB012200: AB_297217, HPA006360: AB_1079082" "unprognostic (2.02e-1)" "unprognostic (2.18e-1)" "unprognostic (1.46e-1)" "unprognostic (2.32e-3)" "unprognostic (8.55e-2)" "prognostic unfavorable (1.35e-5)" "unprognostic (1.58e-2)" "unprognostic (4.77e-3)" "unprognostic (4.93e-2)" "unprognostic (2.02e-2)" "unprognostic (7.05e-2)" "unprognostic (1.38e-3)" "unprognostic (6.00e-2)" "unprognostic (2.12e-1)" "unprognostic (2.04e-1)" "unprognostic (2.70e-2)" "unprognostic (1.51e-1)" 15.6 26.2 37.3 24.3 39.4 54.7 20.4 26.0 63.7 13.6 22.9 25.5 20.4 14.0 62.7 20.3 16.9 14.6 24.5 40.3 47.1 45.5 45.8 14.5 32.1 31.2 32.1 16.8 37.1 21.9 31.5 16.3 34.7 15.4 23.5 74.1 13.5 16.0 22.6 14.8 26.5 17.3 24.6 16.9 32.2 76.1 31.4 31.3 22.1 17.8 30.6 25.4 13.9 31.3 138.0 64.9 18.0 37.2 39.4 56.1 54.1 71.6 68.7 89.5 116.8 58.7 85.5 154.4 158.7 46.7 106.8 82.0 117.4 98.2 153.4 129.2 219.3 84.0 85.0 60.2 38.9 182.9 74.0 41.6 36.1 80.1 126.4 49.5 104.9 90.3 65.5 3.8 71.0 141.0 141.9 157.0 37.0 160.7 171.8 83.8 91.1 158.6 109.6 65.7 113.0 61.6 51.7 41.5 50.1 48.8 35.5 75.2 52.4 60.5 45.6 175.0 181.5 56.5 105.1 0.9 74.6 199.5 33.8 5.8 21.9 20.4 20.8 36.5 30.0 24.0 30.4 27.6 37.9 24.8 24.8 26.9 5.6 39.4 35.5 15.7 57.4 25.3 37.3 39.4 26.0 63.7 40.3 47.1 31.2 32.1 34.7 24.6 31.4 31.3 32.1 19.2 8.2 11.1 39.6 39.6 55.7 75.6 18.8 38.3 26.4 22.0 23.8 30.0 29.9 57.0 4.2 17.9 28.1 16.8 226.9 50.1 11.9 30.1 28.3 39.2 27.5 101.8 55.3 32.3 30.5 29.5 30.1 41.8 34.9 29.0 20.7 22.2 71.2 25.2 43.1 30.4 63.1 60.7 81.7 32.2 40.7 56.2 55.2 10.3 122.5 37.2 26.8 22.1 30.7 36.6 28.2 26.7 30.9 78.1 24.1 30.2 28.9 78.0 52.6 31.6 39.4 213.5 172.6 40.4 38.8 6.0 53.8 30.2 51.3 46.8 HSD17B1 "EDH17B2, EDHB17, HSD17, MGC138140, SDR28C1" ENSG00000108786 "Hydroxysteroid 17-beta dehydrogenase 1" P14061 17 42552922-42555214 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "placenta: 82.3" "Group enriched" "Detected in many" 4 "Granulosa cells: 1574.2;Syncytiotrophoblasts: 1495.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in many" 8 "BEWO: 399.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA021032, HPA065296" Enhanced Supported Cytosol NA NA 19000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" Cytosol "HPA021032: AB_1844345, HPA065296: AB_2685457" "unprognostic (1.13e-1)" "unprognostic (1.40e-2)" "unprognostic (1.68e-2)" "unprognostic (9.25e-2)" "unprognostic (1.73e-1)" "unprognostic (3.88e-2)" "unprognostic (1.14e-1)" "unprognostic (1.10e-1)" "unprognostic (9.35e-2)" "unprognostic (6.04e-2)" "unprognostic (2.88e-5)" "unprognostic (2.17e-1)" "unprognostic (1.30e-1)" "unprognostic (2.60e-2)" "unprognostic (5.09e-1)" "unprognostic (4.98e-1)" "unprognostic (1.32e-2)" 4.4 1.9 3.8 1.7 4.2 0.8 3.0 3.9 4.6 3.0 2.7 2.2 2.1 2.1 0.7 6.0 3.2 0.5 2.1 3.8 3.5 2.4 2.0 1.5 1.0 4.8 3.5 6.8 3.0 0.6 2.4 82.3 4.4 2.6 0.1 0.6 3.7 0.5 4.4 6.3 2.1 0.2 3.2 2.0 2.2 3.8 3.9 0.4 2.8 0.0 0.4 1.7 3.1 6.1 7.0 6.0 1.8 20.2 1.0 0.3 399.0 4.3 0.0 0.0 0.0 2.9 2.8 0.1 4.0 0.2 1.8 9.7 0.7 3.9 0.0 7.6 10.7 3.7 3.8 4.3 0.9 2.7 3.9 0.9 13.2 0.5 2.7 1.5 0.1 2.6 5.7 1.2 0.0 4.8 3.2 2.3 0.4 1.4 2.8 3.9 3.0 2.5 0.5 3.4 4.3 5.6 2.4 41.4 4.2 0.9 48.5 1.1 4.3 2.7 5.4 2.4 2.7 7.7 4.6 1.5 1.9 1.9 2.8 1.0 2.2 2.5 1.1 2.4 1.3 1.2 1.4 1.1 1.3 1.4 1.0 1.0 2.2 1.6 1.5 0.9 0.8 2.0 3.8 4.2 3.9 4.6 3.8 3.5 4.8 3.5 4.4 3.2 3.9 6.1 2.3 0.0 2.2 6.5 2.2 3.1 8.0 14.9 6.2 8.3 11.6 10.7 3.0 4.3 5.3 5.5 12.5 333.0 3.3 4.7 23.5 1.7 1.4 3.3 9.3 4.2 4.2 0.8 1.4 5.6 30.4 11.6 1.5 3.8 2.5 1574.2 3.6 6.4 29.7 10.1 1.6 2.7 8.2 0.6 1.2 1.9 1.8 3.6 1.8 1.9 1.0 11.2 2.1 2.0 3.3 2.0 2.0 3.4 1.4 11.6 2.5 20.5 4.2 8.9 0.0 6.7 29.2 0.8 2.7 14.6 7.4 1495.8 2.6 30.0 2.6 10.4 HSPA1L "HSP70-HOM, hum70t" ENSG00000204390 "Heat shock protein family A (Hsp70) member 1 like" P34931 6 31809619-31815283 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 16 "testis: 63.2" "Group enriched" "Detected in many" 22 "Early spermatids: 212.5;Late spermatids: 560.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 1.1;EFO-21: 1.5;HEK 293: 4.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA043285, HPA052504" Enhanced Approved Nucleoplasm,Vesicles NA NA 53000000 "Cluster 83: Testis - Spermatogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" Vesicles Nucleoplasm "HPA043285: AB_10962482, HPA052504: AB_2681854" "unprognostic (1.80e-1)" "unprognostic (8.70e-2)" "unprognostic (2.52e-3)" "unprognostic (6.97e-4)" "unprognostic (2.69e-2)" "unprognostic (1.17e-2)" "unprognostic (4.24e-2)" "unprognostic (4.33e-2)" "unprognostic (1.71e-1)" "prognostic favorable (1.02e-4)" "unprognostic (5.26e-3)" "unprognostic (9.96e-2)" "prognostic favorable (4.63e-4)" "unprognostic (4.48e-2)" "unprognostic (4.30e-1)" "unprognostic (1.02e-1)" "unprognostic (1.53e-3)" 1.2 1.4 0.0 0.0 0.2 0.1 0.9 1.4 0.3 1.5 0.0 1.8 0.1 1.8 0.0 0.6 2.4 0.0 1.4 0.1 0.2 1.5 1.2 1.3 0.0 0.2 0.2 2.2 0.9 0.0 1.7 0.0 0.3 1.1 0.0 0.1 1.0 0.0 3.9 1.0 1.5 0.0 0.2 2.4 1.3 63.2 0.4 0.0 1.5 0.1 0.0 1.6 1.1 0.6 0.1 1.1 0.1 0.4 0.3 0.3 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 1.5 0.0 0.4 0.4 0.1 0.0 0.1 0.3 4.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.3 0.4 0.0 0.0 0.0 0.0 0.6 0.3 0.0 0.1 0.3 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.4 0.3 0.1 0.2 0.2 0.2 0.3 0.2 0.4 0.6 4.2 0.0 1.1 2.9 3.5 0.9 1.3 0.4 2.2 2.6 1.9 2.0 4.5 0.0 0.9 0.0 8.4 0.6 1.4 1.4 0.0 0.7 212.5 2.0 0.7 2.2 1.8 3.2 0.6 0.2 0.6 1.3 0.0 1.3 0.0 0.9 1.8 1.1 1.3 3.3 0.8 1.4 0.0 4.4 2.5 560.9 5.0 2.1 5.4 2.8 4.1 3.6 1.0 0.5 2.0 0.4 1.4 2.2 1.9 0.9 0.9 0.6 2.2 2.8 0.0 0.8 2.9 17.0 8.7 1.7 0.1 0.4 3.8 0.9 1.5 0.3 HSPB3 HSPL27 ENSG00000169271 "Heat shock protein family B (small) member 3" Q12988 5 54455699-54456377 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Stress response" "Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 17 "heart muscle: 406.9;skeletal muscle: 217.2;tongue: 218.9" "Cell type enriched" "Detected in some" 18 "Cardiomyocytes: 398.1" "Cancer enriched" "Detected in many" 6 "head and neck cancer: 7.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 86.3;fHDF/TERT166: 39.1;HSkMC: 16.3;LHCN-M2: 12.6" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA062124 Supported "Nuclear speckles" NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nuclear speckles" "HPA062124: AB_2684690" "unprognostic (1.44e-1)" "unprognostic (2.21e-1)" "unprognostic (1.78e-3)" "unprognostic (3.06e-1)" "unprognostic (2.25e-3)" "unprognostic (1.13e-1)" "unprognostic (4.41e-3)" "unprognostic (6.42e-2)" "unprognostic (1.85e-1)" "unprognostic (2.70e-2)" "unprognostic (2.73e-1)" "unprognostic (2.82e-2)" "unprognostic (7.15e-2)" 1.4 0.2 4.6 0.1 5.6 0.2 2.1 4.0 7.5 0.9 4.1 5.2 0.2 7.5 0.4 16.5 3.0 0.2 406.9 6.3 7.2 0.4 0.1 2.8 0.0 4.1 4.0 1.0 0.1 0.0 3.6 0.1 4.4 8.6 2.1 1.6 6.7 0.8 217.2 2.2 0.9 10.4 4.1 0.7 0.9 1.8 4.1 0.7 0.3 218.9 0.0 3.7 0.8 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 86.3 0.1 0.1 0.4 0.0 0.0 0.3 39.1 0.1 4.8 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.4 0.0 0.0 16.3 5.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 12.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 4.4 0.1 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.6 5.6 4.0 7.5 6.3 7.2 4.1 4.0 4.4 4.1 4.1 6.4 0.0 0.0 0.0 0.3 0.0 6.4 0.4 3.2 0.0 0.1 0.0 0.0 398.1 0.0 0.3 0.0 0.0 0.1 0.0 10.5 0.0 0.0 0.1 0.7 0.2 3.5 0.0 0.0 4.3 0.0 0.0 14.4 0.0 1.3 0.0 0.1 0.0 0.0 0.1 1.7 6.5 0.0 0.0 0.0 4.9 0.4 0.6 0.2 3.6 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.5 6.6 21.3 7.2 0.4 0.0 0.0 5.3 0.1 0.2 0.1 0.3 0.3 HTATIP2 "CC3, FLJ26963, SDR44U1, TIP30" ENSG00000109854 "HIV-1 Tat interactive protein 2" Q9BUP3 11 20363685-20383782 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Apoptosis, Differentiation, Host-virus interaction" "Developmental protein, Oxidoreductase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 269.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 283.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006417, HPA024321" Approved Supported Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA006417: AB_1079091, HPA024321: AB_1851288" "unprognostic (8.05e-3)" "unprognostic (2.13e-1)" "unprognostic (9.31e-2)" "unprognostic (3.01e-1)" "unprognostic (1.36e-2)" "unprognostic (3.79e-3)" "prognostic unfavorable (2.86e-4)" "unprognostic (1.20e-3)" "unprognostic (1.05e-1)" "unprognostic (4.93e-2)" "prognostic unfavorable (6.18e-4)" "unprognostic (1.75e-1)" "prognostic unfavorable (8.01e-4)" "unprognostic (1.20e-1)" "unprognostic (9.42e-2)" "unprognostic (1.71e-1)" "unprognostic (2.03e-1)" 30.0 57.5 29.6 32.3 35.9 18.6 29.6 33.2 46.1 24.2 34.7 88.4 135.9 13.8 31.4 50.0 13.5 44.8 21.2 29.2 31.3 32.6 97.8 39.1 28.5 34.1 31.7 16.2 26.7 27.8 39.9 28.5 34.6 22.4 80.7 1.9 35.0 20.6 46.2 36.0 121.4 14.4 32.3 38.6 75.4 21.4 32.3 20.2 51.3 21.3 27.4 37.7 35.4 45.8 109.6 177.5 3.9 0.2 52.5 39.4 38.7 46.4 45.8 35.3 41.8 103.2 93.8 24.8 93.1 58.3 136.6 149.7 0.0 28.2 33.9 283.9 21.4 30.8 170.1 0.2 125.3 11.3 139.6 57.3 196.0 28.7 44.5 0.0 102.2 0.0 76.8 31.6 66.3 102.0 0.4 7.0 56.5 193.2 87.1 23.2 0.3 89.8 48.1 60.1 47.2 0.5 150.9 59.1 73.6 18.0 123.7 57.0 125.4 25.1 54.8 51.0 1.2 33.5 44.7 0.6 0.4 76.9 111.4 233.4 133.3 171.1 64.3 126.4 73.4 65.9 74.1 69.2 76.9 76.4 63.9 62.7 304.1 64.5 135.2 23.2 140.9 116.7 29.6 35.9 33.2 46.1 29.2 31.3 34.1 31.7 34.6 32.3 32.3 45.8 49.2 25.6 9.6 3.9 28.0 36.3 60.0 74.2 67.2 1.0 32.9 26.7 11.6 102.9 43.7 47.8 0.0 53.7 16.7 175.6 31.3 91.4 51.1 19.3 6.1 29.5 24.1 28.8 12.9 72.3 118.0 23.8 49.5 34.5 22.9 22.7 33.2 77.5 82.8 3.3 9.1 100.3 105.8 54.0 27.6 59.5 19.9 61.3 44.4 8.4 114.6 9.5 39.1 3.5 40.2 94.7 157.3 9.4 21.4 65.2 269.7 69.0 37.4 1.7 13.1 19.2 28.5 45.5 21.5 87.2 42.1 61.6 33.4 13.2 87.8 62.7 HVCN1 "Hv1, MGC15619, VSOP" ENSG00000122986 "Hydrogen voltage gated channel 1" Q96D96 12 110627841-110704950 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 162.1;lymphoid tissue: 72.9" "Cell type enhanced" "Detected in many" "B-cells: 178.4;Early spermatids: 87.3;Hofbauer cells: 57.0;Late spermatids: 76.4;Spermatocytes: 117.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 4 "NB-4: 286.4;U-698: 90.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA039329 Enhanced NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 24: NB-4 - Immune response" "Cluster 57: B-cells - Immune response" "HPA039329: AB_10674284" "unprognostic (3.43e-2)" "unprognostic (6.32e-3)" "unprognostic (7.05e-2)" "unprognostic (1.54e-2)" "unprognostic (4.62e-3)" "unprognostic (3.89e-2)" "unprognostic (1.96e-1)" "unprognostic (5.85e-3)" "unprognostic (2.40e-1)" "unprognostic (3.09e-2)" "unprognostic (1.54e-2)" "unprognostic (5.67e-2)" "unprognostic (3.35e-3)" "unprognostic (4.82e-2)" "unprognostic (1.33e-1)" "unprognostic (1.79e-1)" "unprognostic (1.68e-1)" 8.2 5.1 23.4 32.0 34.7 6.9 5.2 24.3 21.1 9.3 162.1 6.5 4.8 10.1 11.5 4.6 9.2 8.3 17.5 26.2 29.5 3.3 4.4 13.7 65.0 25.7 32.8 13.5 1.7 2.2 3.0 8.1 27.8 6.4 6.7 2.7 3.9 8.7 7.9 3.0 17.8 10.3 20.2 42.7 7.6 44.7 27.6 16.2 3.9 9.8 72.9 9.7 5.2 25.0 0.1 0.5 2.8 0.2 4.5 4.7 1.4 0.9 1.1 2.6 1.4 0.5 0.0 2.9 2.4 5.1 0.0 0.4 3.3 0.2 3.7 0.2 0.6 0.1 0.3 0.7 4.0 44.1 3.1 6.2 0.4 2.4 0.0 0.4 6.4 13.4 1.9 2.4 4.7 0.2 6.4 286.4 3.2 0.0 2.7 5.4 0.2 0.3 0.0 0.1 0.3 0.4 0.1 0.0 0.2 2.9 0.0 42.8 1.9 0.0 0.2 0.4 0.1 27.4 3.7 90.5 0.3 2.2 0.2 378.0 208.3 675.7 14.0 197.8 7.7 550.4 13.2 22.7 88.7 799.8 25.2 17.2 327.4 182.6 185.0 131.7 31.0 193.2 23.4 34.7 24.3 21.1 26.2 29.5 25.7 32.8 27.8 20.2 27.6 25.0 18.4 3.2 5.3 9.4 178.4 0.8 1.9 2.0 1.2 0.5 1.2 2.8 6.6 0.0 3.6 1.8 0.0 0.4 25.8 0.0 0.0 0.5 87.3 0.5 5.8 13.1 0.0 0.8 0.6 0.2 1.4 5.4 1.5 0.3 8.2 3.9 12.1 0.3 57.0 0.0 0.5 0.2 0.0 41.7 17.2 76.4 13.4 42.2 12.4 15.0 31.6 15.2 23.7 2.0 0.1 0.5 0.1 13.9 9.9 0.6 0.0 0.5 1.7 1.8 13.1 4.7 15.1 117.5 2.8 0.7 0.4 1.2 7.6 0.5 0.2 1.2 HYAL3 "LUCA-3, LUCA14, Minna14" ENSG00000186792 "Hyaluronidase 3" O43820 3 50292831-50299405 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" Fertilization "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 36.4" "Group enriched" "Detected in many" 17 "Early spermatids: 79.7;Late spermatids: 268.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 33.2;eosinophil: 54.6" "Lineage enriched" "Detected in all" 7 "granulocytes: 54.6" "Cell line enhanced" "Detected in all" "HEL: 58.8;HMC-1: 101.1;THP-1: 107.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in single" HPA049402 Uncertain "Secreted to blood" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 31: Spermatids - Spermatogenesis" "HPA049402: AB_2680746" "unprognostic (1.21e-3)" "unprognostic (2.55e-2)" "unprognostic (5.45e-2)" "unprognostic (8.19e-2)" "unprognostic (3.07e-1)" "unprognostic (1.65e-2)" "unprognostic (7.98e-3)" "unprognostic (7.36e-2)" "unprognostic (1.58e-1)" "unprognostic (3.41e-2)" "unprognostic (5.40e-2)" "unprognostic (5.71e-2)" "unprognostic (2.61e-1)" "unprognostic (8.09e-2)" "unprognostic (1.28e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (2.12e-5)" 2.1 2.8 5.1 1.3 5.4 36.4 1.8 6.7 8.3 2.0 2.9 1.9 1.7 1.6 1.1 3.9 1.6 1.8 1.8 5.1 4.0 2.6 5.1 2.1 1.2 7.4 4.0 1.5 1.9 0.9 1.9 1.5 7.3 3.2 1.0 1.1 3.5 2.4 1.0 2.1 1.8 2.2 3.9 1.7 4.5 13.9 5.4 1.6 1.7 0.9 1.6 1.8 2.7 5.8 6.0 6.9 3.8 4.3 7.6 3.9 2.3 6.5 5.8 8.0 6.1 9.3 6.2 5.2 3.1 7.5 12.4 6.5 7.0 15.2 3.0 12.3 3.6 58.8 18.8 7.6 5.5 6.4 101.1 8.1 11.5 8.1 5.2 5.8 8.4 5.8 4.6 6.3 3.8 3.6 2.4 37.4 2.9 7.0 17.2 2.6 5.1 9.5 9.5 2.6 4.7 5.4 9.6 7.5 5.1 4.4 4.9 107.2 11.1 6.8 4.9 22.2 3.8 3.0 7.0 4.4 6.0 22.5 5.8 33.2 4.1 54.6 1.3 2.3 2.2 1.6 4.1 1.9 8.2 2.9 1.1 1.5 1.4 2.1 1.4 2.0 2.6 2.4 5.1 5.4 6.7 8.3 5.1 4.0 7.4 4.0 7.3 3.9 5.4 5.8 2.5 3.2 1.1 0.3 0.8 3.1 2.8 8.1 2.8 1.5 2.2 2.8 0.4 1.5 5.0 3.7 4.2 2.8 0.2 0.8 9.8 5.6 79.7 2.0 1.6 3.5 4.2 9.2 2.4 0.7 5.3 1.2 4.1 2.1 7.0 1.1 7.1 2.1 2.1 5.0 1.6 1.9 6.1 1.9 4.4 268.2 1.8 2.0 3.6 1.0 5.9 1.5 0.0 0.5 0.3 3.6 0.4 2.6 1.9 2.2 0.5 2.7 1.8 0.8 6.6 1.2 1.8 4.3 4.6 3.7 3.7 3.0 2.2 1.6 1.8 3.5 ICAM2 CD102 ENSG00000108622 "Intercellular adhesion molecule 2" P13598 17 64002594-64020634 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 168.1" "Cell type enhanced" "Detected in many" "Adipocytes: 341.8;Endothelial cells: 180.8;Hepatic stellate cells: 128.5;NK-cells: 106.1;Plasma cells: 114.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 6 "HUVEC TERT2: 1260.8;TIME: 319.0" "Low region specificity" "Detected in all" HPA071155 Approved "Plasma membrane,Cytosol" NA NA 730000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" Cytosol "HPA071155: " "unprognostic (9.43e-3)" "unprognostic (3.31e-2)" "unprognostic (5.15e-2)" "unprognostic (1.15e-1)" "unprognostic (8.97e-2)" "unprognostic (1.64e-3)" "unprognostic (1.34e-1)" "unprognostic (3.74e-1)" "unprognostic (8.28e-2)" "unprognostic (2.15e-1)" "unprognostic (4.18e-2)" "unprognostic (1.55e-2)" "unprognostic (9.07e-2)" "unprognostic (1.48e-1)" "unprognostic (3.93e-2)" "unprognostic (6.04e-2)" "unprognostic (2.29e-1)" 97.4 11.3 39.6 30.4 39.6 20.7 78.7 40.3 48.3 20.3 34.6 26.3 14.1 24.4 6.7 12.1 22.2 18.8 99.7 38.2 40.5 44.3 14.6 84.5 60.5 42.1 40.9 12.7 15.4 9.0 12.4 79.3 42.9 16.1 18.2 1.2 16.0 8.6 37.9 16.3 34.2 29.5 41.4 168.1 18.8 3.5 44.6 31.5 33.6 55.9 41.8 33.0 21.4 40.6 0.0 0.0 0.0 0.0 11.3 10.8 3.2 1.1 0.7 0.3 1.1 2.7 52.2 92.9 16.6 0.0 0.3 0.4 1.2 0.0 1.7 22.3 0.0 82.9 4.4 10.0 1.8 14.2 0.3 0.4 0.0 0.8 0.2 0.0 1260.8 78.8 67.7 50.5 0.3 0.0 101.8 11.8 0.1 0.7 0.0 60.3 0.2 128.7 6.7 12.8 0.0 0.8 0.0 0.2 0.0 0.1 0.0 10.3 319.0 0.2 0.8 6.2 0.0 47.6 18.7 83.4 0.1 17.7 0.0 444.8 191.8 62.1 282.8 464.6 326.0 265.6 371.2 270.7 203.6 328.9 400.3 253.3 23.1 188.5 525.8 67.2 450.8 502.0 39.6 39.6 40.3 48.3 38.2 40.5 42.1 40.9 42.9 41.4 44.6 40.6 341.8 0.0 8.4 0.0 47.8 7.4 4.0 5.2 0.6 0.1 6.1 11.3 0.5 1.5 4.5 7.3 0.0 0.5 41.7 1.7 0.0 1.2 0.6 1.2 2.4 180.8 1.2 28.2 0.1 1.4 0.3 13.8 1.1 0.8 12.0 0.7 128.5 1.9 20.0 0.0 0.0 2.2 2.0 55.6 13.4 1.3 0.3 56.9 28.4 21.5 25.7 0.4 106.1 0.5 0.2 6.8 4.7 1.9 114.4 3.8 0.6 0.5 4.1 0.5 6.6 7.4 11.6 0.2 0.3 0.7 5.4 1.0 60.1 6.5 4.2 2.8 ID3 "bHLHb25, HEIR-1" ENSG00000117318 "Inhibitor of DNA binding 3, HLH protein" Q02535 1 23557926-23559501 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Myogenesis, Transcription, Transcription regulation" Repressor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 1710.3;Basal respiratory cells: 1091.1;Hepatic stellate cells: 1508.2;Ionocytes: 1210.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 318.8;naive B-cell: 306.1" "Group enriched" "Detected in many" 39 "B-cells: 318.8;T-cells: 177.0" "Cell line enhanced" "Detected in many" "U-698: 598.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB021353, HPA024677" Approved Supported Nucleoplasm NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 72: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "CAB021353: , HPA024677: AB_2671647" "unprognostic (6.73e-2)" "unprognostic (2.48e-1)" "unprognostic (5.19e-2)" "prognostic favorable (1.27e-5)" "unprognostic (5.58e-3)" "unprognostic (1.46e-1)" "unprognostic (8.98e-2)" "unprognostic (7.76e-2)" "unprognostic (3.89e-2)" "unprognostic (6.47e-3)" "unprognostic (2.42e-1)" "unprognostic (1.50e-1)" "unprognostic (2.52e-2)" "unprognostic (1.36e-1)" "unprognostic (2.01e-1)" "unprognostic (4.37e-3)" "unprognostic (8.36e-2)" 163.4 49.5 42.5 22.7 37.4 6.9 114.1 38.6 51.6 81.6 39.6 89.2 29.8 84.2 15.5 42.9 134.1 39.1 177.1 39.2 70.3 93.2 31.6 99.6 26.3 59.3 52.2 106.1 41.0 8.3 120.4 51.0 49.5 110.3 22.3 10.1 39.8 108.1 41.3 62.9 76.3 20.9 48.2 41.9 89.0 6.9 53.7 34.8 195.9 52.1 13.3 131.6 90.3 42.9 24.1 152.6 57.2 199.1 27.2 2.8 53.0 154.2 16.8 105.0 14.5 8.9 1.2 150.2 168.2 80.3 21.7 216.1 77.7 25.1 12.3 1.2 68.8 2.4 227.5 89.6 77.9 0.2 0.4 80.1 141.9 2.8 1.5 104.0 91.7 67.1 0.9 2.0 107.8 59.9 21.0 0.6 41.9 140.0 37.6 189.5 82.1 5.6 1.3 66.3 78.3 55.0 148.4 155.8 12.7 49.9 38.1 5.2 162.3 151.5 72.4 69.4 92.2 47.4 45.9 598.1 34.4 1.8 79.0 0.6 1.3 0.3 3.8 1.8 1.3 318.8 69.8 13.9 5.0 306.1 113.3 45.6 3.6 0.7 2.1 6.2 177.0 36.9 42.5 37.4 38.6 51.6 39.2 70.3 59.3 52.2 49.5 48.2 53.7 42.9 1710.3 115.4 62.6 77.7 211.6 205.2 340.3 1091.1 583.4 4.1 128.3 187.3 35.8 20.0 337.1 209.7 10.4 193.4 27.8 384.8 23.5 216.6 1.9 555.2 270.3 988.8 432.3 41.0 0.1 441.5 931.4 496.5 384.3 562.4 15.2 394.7 1508.2 7.0 70.6 5.0 0.2 560.1 1210.5 71.7 254.9 3.7 41.0 91.1 249.1 62.8 21.0 378.5 1.0 0.5 3.1 88.4 388.8 0.7 67.1 168.4 223.1 7.9 110.6 17.7 519.4 266.4 780.2 0.9 2.8 577.6 189.5 279.2 86.7 19.5 323.3 116.5 IDO2 INDOL1 ENSG00000188676 "Indoleamine 2,3-dioxygenase 2" Q6ZQW0 8 39934614-40016391 "Metabolic proteins, Predicted intracellular proteins" "Immunity, Tryptophan catabolism" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "liver: 5.4;placenta: 4.0" "Cell type enhanced" "Detected in some" "Early spermatids: 21.0;Endometrial ciliated cells: 18.4;Glandular and luminal cells: 51.3;Late spermatids: 6.9;monocytes: 14.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA054911 Approved Cytosol NA NA "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 44: Endometrium - Transcription" Cytosol "HPA054911: " "unprognostic (2.00e-3)" "unprognostic (2.34e-5)" "unprognostic (2.22e-3)" "unprognostic (4.41e-3)" "unprognostic (5.37e-2)" "unprognostic (3.69e-5)" "unprognostic (1.19e-1)" "unprognostic (4.73e-3)" "unprognostic (1.20e-2)" "unprognostic (2.78e-1)" "unprognostic (4.11e-3)" "unprognostic (2.25e-1)" "unprognostic (6.47e-7)" "unprognostic (3.25e-2)" "unprognostic (1.96e-3)" "unprognostic (3.35e-2)" "unprognostic (3.08e-3)" 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 5.4 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 4.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.2 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.9 0.1 21.0 18.4 4.4 0.2 0.0 0.0 0.3 0.0 0.0 0.1 0.0 51.3 0.0 0.0 0.0 2.6 0.2 0.0 0.4 0.0 0.0 0.0 1.9 6.9 0.3 0.8 0.0 0.0 14.6 0.0 0.0 0.5 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.1 0.1 0.4 0.2 0.0 0.3 0.0 0.4 0.0 0.0 0.1 IFRD2 "IFNRP, SKMc15, SM15" ENSG00000214706 "Interferon related developmental regulator 2" Q12894 3 50287732-50292918 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 139.9;Prostatic glandular cells: 153.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068560 Approved Approved Nucleoplasm NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "HPA068560: AB_2686005" "prognostic favorable (7.22e-4)" "unprognostic (5.19e-2)" "unprognostic (2.08e-2)" "unprognostic (8.61e-3)" "unprognostic (3.88e-1)" "unprognostic (2.30e-2)" "unprognostic (1.19e-2)" "unprognostic (2.24e-1)" "unprognostic (1.62e-1)" "unprognostic (2.01e-1)" "unprognostic (1.91e-2)" "unprognostic (7.78e-3)" "prognostic favorable (2.50e-4)" "unprognostic (3.07e-2)" "unprognostic (1.03e-1)" "unprognostic (1.58e-1)" "unprognostic (1.13e-1)" 39.4 44.9 16.7 13.9 17.8 15.6 33.9 17.4 20.9 24.4 19.2 33.2 20.1 26.8 11.8 44.3 28.2 10.9 69.4 16.2 16.6 39.3 97.0 30.7 14.1 18.0 17.7 23.1 87.3 17.8 22.1 9.3 17.2 45.1 15.0 3.6 33.7 16.7 109.6 25.4 28.1 14.9 17.9 28.3 67.9 17.4 18.0 8.4 31.9 44.6 12.5 36.1 23.6 18.0 70.1 70.5 19.1 60.3 19.2 22.0 44.0 52.4 28.2 62.8 44.3 58.3 69.5 47.3 37.7 36.3 53.9 40.0 40.2 83.8 32.3 45.4 80.7 68.4 93.5 69.5 37.9 70.1 41.4 20.4 70.6 65.7 81.9 20.7 54.0 41.8 44.2 37.9 37.6 65.1 46.5 82.0 48.1 86.1 135.4 29.8 27.7 108.1 38.0 41.3 33.7 32.5 33.2 90.4 34.4 18.3 43.1 66.4 39.5 52.2 65.6 91.3 107.9 26.5 48.9 41.8 41.4 91.1 77.9 11.7 24.1 3.6 33.1 34.4 47.5 32.4 35.0 32.3 35.2 34.0 36.7 33.3 2.3 39.0 19.7 35.0 30.9 30.5 16.7 17.8 17.4 20.9 16.2 16.6 18.0 17.7 17.2 17.9 18.0 18.0 36.9 19.2 24.6 5.9 26.8 67.3 71.7 51.7 31.9 17.3 48.5 37.1 1.7 32.9 36.4 20.2 20.9 35.3 23.8 22.1 29.4 68.8 67.2 11.3 27.8 30.3 15.6 93.6 7.1 89.6 49.5 24.8 62.7 13.1 7.6 28.6 13.9 50.7 31.2 18.5 6.7 29.6 34.6 13.7 28.4 139.9 13.7 15.2 35.6 2.8 16.5 13.3 25.7 4.5 7.3 68.2 26.8 14.3 31.9 153.3 31.3 58.6 10.4 12.0 0.0 30.8 34.9 21.9 19.1 43.1 68.6 30.4 19.2 40.3 56.3 76.8 IFT46 "C11orf2, C11orf60, CFAP32, FLJ21827" ENSG00000118096 "Intraflagellar transport 46" Q9NQC8 11 118544528-118572970 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 64.9;Respiratory ciliated cells: 84.3;Spermatocytes: 44.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037909, HPA057550" Approved Approved "Actin filaments" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 49: Ciliated cells - Cilium organization" "Actin filaments" "HPA037909: AB_10672731, HPA057550: AB_2683464" "unprognostic (8.77e-2)" "unprognostic (1.22e-1)" "unprognostic (2.79e-1)" "unprognostic (2.35e-3)" "unprognostic (6.76e-2)" "unprognostic (1.55e-2)" "unprognostic (1.07e-1)" "unprognostic (3.29e-2)" "unprognostic (3.75e-3)" "unprognostic (1.47e-1)" "unprognostic (1.37e-1)" "unprognostic (3.61e-1)" "unprognostic (9.02e-3)" "unprognostic (1.42e-1)" "unprognostic (2.48e-1)" "unprognostic (6.53e-2)" "unprognostic (2.41e-1)" 14.7 19.4 29.0 8.8 29.7 5.6 26.8 33.9 35.8 23.1 37.3 18.6 7.7 19.4 24.8 13.7 66.8 16.4 21.3 28.5 32.5 26.9 17.0 15.1 11.0 32.1 37.2 27.2 16.7 18.4 28.9 8.7 31.8 20.9 11.1 35.7 15.9 20.2 17.9 13.5 10.3 20.7 31.5 11.8 15.0 28.1 31.4 16.0 27.5 17.6 12.8 16.0 16.7 32.1 15.6 18.4 26.1 16.9 42.8 35.7 3.2 31.9 46.2 29.3 27.6 22.5 28.8 23.8 46.1 38.6 7.2 22.1 26.7 31.8 34.4 9.1 21.8 49.2 9.0 8.6 32.0 11.8 13.8 32.4 37.0 49.0 46.2 26.6 28.9 32.1 27.4 16.0 37.3 71.7 31.3 15.6 7.7 27.3 38.0 25.6 20.0 19.0 23.5 21.4 16.7 18.3 23.2 29.9 20.1 15.0 46.2 16.7 24.6 31.6 20.2 18.4 12.0 9.9 14.3 26.7 16.0 21.2 23.2 2.8 5.2 5.9 8.6 4.3 9.9 11.1 7.6 7.9 6.9 8.3 9.2 5.5 1.6 11.0 4.2 7.0 9.9 4.8 29.0 29.7 33.9 35.8 28.5 32.5 32.1 37.2 31.8 31.5 31.4 32.1 5.5 9.6 10.3 10.4 4.9 4.0 8.3 14.4 8.0 12.5 11.6 8.4 14.5 10.0 15.4 11.0 18.8 5.3 3.8 1.6 5.9 17.1 20.5 64.9 11.7 9.3 4.2 6.6 8.7 11.6 7.1 9.5 4.1 9.6 12.0 10.2 8.6 5.9 8.8 1.7 8.9 4.3 14.2 2.4 3.5 15.7 10.2 3.1 1.8 5.6 5.5 14.8 2.1 4.0 6.4 10.2 4.2 18.4 6.1 6.1 3.4 14.3 84.3 16.5 0.0 11.3 11.5 44.9 38.4 6.5 7.0 1.9 4.2 9.8 5.3 3.9 IFTAP "C11orf74, FLJ38678, HEPIS, NWC" ENSG00000166352 "Intraflagellar transport associated protein" Q86VG3 11 36594369-36675695 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 10.0;Cardiomyocytes: 60.7;Cytotrophoblasts: 19.3;Extravillous trophoblasts: 19.0;Fibroblasts: 8.5;Hofbauer cells: 26.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044880 Uncertain Approved Aggresome,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 24: Non-specific - Transcription regulation" "Aggresome, Cytosol" "HPA044880: AB_10796908" "unprognostic (9.22e-3)" "unprognostic (6.79e-2)" "unprognostic (3.23e-2)" "unprognostic (7.47e-2)" "unprognostic (5.00e-3)" "unprognostic (1.13e-2)" "unprognostic (1.13e-2)" "unprognostic (9.86e-2)" "unprognostic (2.36e-1)" "unprognostic (3.65e-2)" "unprognostic (8.52e-2)" "unprognostic (1.92e-1)" "unprognostic (1.95e-2)" "unprognostic (1.37e-2)" "unprognostic (1.17e-2)" "unprognostic (1.24e-1)" "unprognostic (3.24e-1)" 17.1 20.0 19.5 5.3 20.0 13.3 15.3 19.7 31.0 17.0 33.0 30.7 7.5 16.2 23.7 9.5 31.7 12.7 45.3 19.7 19.1 25.3 18.7 11.8 5.4 19.3 20.0 21.8 18.0 16.5 25.9 10.3 19.4 12.8 10.4 19.5 12.2 10.3 41.0 7.2 10.1 16.5 18.9 8.3 17.5 52.4 19.8 10.5 82.2 42.3 5.0 17.5 12.9 20.1 11.4 19.7 41.4 31.3 39.0 56.2 16.4 24.5 26.8 23.6 43.3 0.7 18.8 0.2 18.1 25.0 32.4 4.5 28.3 33.9 48.8 0.2 47.8 19.9 9.2 20.0 30.0 27.4 4.5 36.4 24.4 15.7 22.4 40.5 40.4 15.2 25.4 0.3 25.6 18.8 4.9 22.7 24.8 7.0 31.0 19.5 51.4 11.3 34.1 3.6 0.6 46.6 28.0 5.4 42.6 37.4 38.3 14.7 24.7 32.3 22.3 43.4 21.8 6.2 12.3 0.0 29.4 33.2 17.0 10.5 18.3 1.2 1.6 15.4 5.1 0.0 4.8 3.9 20.9 0.3 11.6 2.9 1.0 14.1 15.3 28.5 0.7 8.3 19.5 20.0 19.7 31.0 19.7 19.1 19.3 20.0 19.4 18.9 19.8 20.1 10.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 60.7 0.0 0.0 0.0 0.0 19.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 19.0 8.5 0.0 0.0 0.0 0.0 0.0 0.0 26.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 IGFBP3 "BP-53, IBP3" ENSG00000146674 "Insulin like growth factor binding protein 3" P17936 7 45912245-45921874 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Apoptosis "Growth factor binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 1864.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 457.7;Basal respiratory cells: 777.7;Extravillous trophoblasts: 2064.1;Fibroblasts: 463.4;Urothelial cells: 809.9" "Cancer enhanced" "Detected in all" "renal cancer: 377.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "plasmacytoid DC: 54.5" "Lineage enriched" "Detected in many" 5 "dendritic cells: 54.5" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 8578.6;U-2197: 3469.4;U-87 MG: 1774.2" "Low region specificity" "Detected in all" CAB010360 Approved Nucleoplasm,Vesicles,Cytosol "Secreted to blood" NA NA 3250000000 3600000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Vesicles "Nucleoplasm, Cytosol" "CAB010360: AB_2233528" "unprognostic (4.46e-3)" "unprognostic (4.84e-2)" "prognostic unfavorable (1.08e-4)" "unprognostic (2.30e-1)" "unprognostic (1.15e-1)" "unprognostic (6.54e-2)" "prognostic unfavorable (1.64e-4)" "unprognostic (8.14e-3)" "unprognostic (3.31e-2)" "unprognostic (2.03e-1)" "unprognostic (9.67e-3)" "unprognostic (2.80e-1)" "prognostic unfavorable (5.07e-7)" "unprognostic (2.36e-2)" "unprognostic (4.14e-2)" "unprognostic (2.37e-3)" "unprognostic (2.63e-1)" 350.6 16.2 15.6 28.5 20.2 1.2 278.2 12.2 24.1 291.8 18.9 96.7 67.8 547.3 43.1 28.2 130.9 44.6 284.6 16.5 22.5 65.9 721.3 37.5 68.3 20.7 13.7 233.1 14.4 28.0 98.1 1864.4 21.0 87.4 58.4 11.9 46.2 81.1 57.9 176.5 77.9 198.1 12.8 191.0 81.7 10.8 16.5 18.2 40.8 73.3 67.4 369.7 165.3 15.9 199.6 59.5 113.1 1.0 83.9 34.7 0.9 850.6 153.8 71.9 38.8 0.2 157.4 0.2 263.2 8578.6 35.6 466.5 1.5 3.4 29.2 0.6 0.1 0.3 20.8 0.2 21.9 0.4 1.6 285.7 12.8 15.1 53.8 112.3 0.7 0.0 0.1 3.2 26.8 1.2 1.3 1.4 7.8 1.8 10.9 0.8 0.4 81.4 53.2 423.6 13.6 32.7 293.9 11.4 15.3 250.6 1.5 0.7 0.5 815.4 1.7 3469.4 49.3 11.6 0.7 1.1 1774.2 0.3 282.1 0.0 0.0 0.0 10.1 0.0 8.0 0.0 10.9 10.7 0.0 0.0 4.9 8.1 0.1 0.0 0.0 54.5 0.8 4.5 15.6 20.2 12.2 24.1 16.5 22.5 20.7 13.7 21.0 12.8 16.5 15.9 260.4 3.2 3.9 0.7 1.9 457.7 148.9 777.7 8.0 2.8 12.6 30.4 12.6 8.6 409.7 228.1 0.0 94.1 10.0 0.7 11.7 145.6 1.3 32.3 220.1 168.0 273.7 5.3 2.5 2.0 2064.1 463.4 1.5 31.3 1.3 12.2 182.0 2.6 80.9 0.0 5.6 8.4 57.0 7.2 21.9 3.5 288.3 3.5 16.0 1.9 7.2 0.6 0.0 0.5 0.2 19.0 2.5 6.8 1.0 212.1 0.8 1.0 136.0 0.5 0.0 12.6 124.6 0.8 1.4 9.3 244.6 154.2 9.3 3.6 2.0 809.9 IGFN1 "DKFZp434B1231, EEF1A2BP1" ENSG00000163395 "Immunoglobulin like and fibronectin type III domain containing 1" Q86VF2 1 201190824-201228952 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "skeletal muscle: 186.3" "Cell type enriched" "Detected in some" 4 "Skeletal myocytes: 103.8" "Cancer enriched" "Detected in some" 4 "thyroid cancer: 8.1" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 11 "HeLa: 76.6" "Group enriched" "Detected in many" 7 "amygdala: 3.3;basal ganglia: 1.2;cerebral cortex: 2.9;hippocampal formation: 1.9" "Low region specificity" "Detected in some" HPA050415 Enhanced Approved "Midbody ring" Yes NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 20: HeLa - Mitochondria" "Cluster 50: Fibroblasts - ECM organization" "Midbody ring" "HPA050415: AB_2681120" "unprognostic (2.09e-1)" "unprognostic (1.63e-3)" "unprognostic (1.82e-2)" "unprognostic (3.25e-1)" "unprognostic (1.02e-2)" "unprognostic (2.00e-2)" "unprognostic (9.80e-3)" "unprognostic (1.73e-1)" "unprognostic (2.02e-2)" "unprognostic (1.51e-1)" "unprognostic (2.07e-1)" "unprognostic (3.80e-2)" "prognostic unfavorable (1.27e-8)" "unprognostic (3.55e-4)" "unprognostic (6.06e-2)" "unprognostic (1.10e-1)" "unprognostic (5.42e-2)" 0.6 0.1 0.3 0.1 0.1 0.0 0.2 0.0 0.3 0.9 0.6 0.1 0.0 10.4 15.1 0.0 0.9 0.2 0.3 1.2 0.6 0.1 0.1 0.5 0.1 0.1 0.2 0.2 7.0 0.0 0.1 0.0 0.0 0.7 0.2 0.0 0.0 0.3 186.3 0.3 0.0 0.8 0.0 0.0 0.1 2.5 0.4 0.0 14.6 0.2 0.0 0.3 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 76.6 0.1 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.8 0.0 4.9 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.3 1.2 0.6 0.1 0.2 0.0 0.0 0.4 0.1 0.0 0.0 0.0 11.1 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.4 0.1 0.0 0.0 0.1 1.5 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 22.1 0.4 1.8 1.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 9.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 103.8 0.7 0.6 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 IGLON5 LOC402665 ENSG00000142549 "IgLON family member 5" A6NGN9 19 51311848-51330354 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 47.2;retina: 13.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 24.4;Horizontal cells: 79.1;Inhibitory neurons: 17.6;Spermatogonia: 9.7" "Group enriched" "Detected in many" 5 "glioma: 9.2;ovarian cancer: 3.5;testis cancer: 12.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 35.0;NTERA-2: 16.0;SH-SY5Y: 23.0;SuSa: 9.9;U-2 OS: 6.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041994 Approved "Secreted in brain" NA NA 15000 "Cluster 73: Brain - Neuropeptide signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 62: Horizontal cells - Visual perception" "HPA041994: AB_10794641" "unprognostic (2.09e-1)" "unprognostic (5.76e-2)" "unprognostic (1.80e-2)" "unprognostic (8.87e-3)" "unprognostic (2.33e-1)" "unprognostic (2.66e-1)" "unprognostic (3.47e-4)" "unprognostic (6.38e-5)" "unprognostic (4.54e-2)" "unprognostic (7.89e-3)" "unprognostic (1.59e-1)" "unprognostic (1.81e-1)" "prognostic unfavorable (5.62e-7)" "unprognostic (1.77e-2)" "unprognostic (9.28e-2)" "unprognostic (1.36e-2)" "unprognostic (1.86e-3)" 1.7 1.7 11.5 0.2 9.0 0.7 0.9 23.4 21.6 0.5 1.1 0.6 0.1 0.1 0.7 4.2 0.1 0.2 0.3 11.7 17.1 0.4 1.9 0.2 0.0 47.2 19.1 1.2 0.2 1.8 1.2 0.4 44.9 0.2 0.0 13.9 0.7 0.7 0.0 0.6 0.3 0.1 16.5 0.1 0.2 8.0 22.2 0.0 0.2 0.0 0.0 0.4 1.2 10.8 0.0 0.3 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.6 0.0 0.4 0.1 0.4 0.0 0.0 0.1 0.2 0.0 0.0 0.3 0.0 0.1 35.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.2 0.0 0.1 16.0 0.2 0.0 0.0 0.0 3.5 0.0 0.1 0.1 23.0 0.0 0.0 0.0 9.9 0.2 2.2 0.0 0.0 6.4 0.1 0.0 0.2 0.3 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 11.5 9.0 23.4 21.6 11.7 17.1 47.2 19.1 44.9 16.5 22.2 10.8 2.1 0.0 0.0 1.3 0.2 0.0 0.0 0.0 0.0 24.4 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.1 0.9 0.0 0.0 6.2 0.0 0.0 0.2 0.0 0.0 0.0 0.4 1.8 0.1 0.3 79.1 17.6 0.0 0.0 0.0 0.0 2.8 0.0 1.1 0.0 3.7 0.0 2.5 0.0 5.5 0.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.9 0.9 9.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 IGSF1 "IGCD1, IGDC1, INHBP, KIAA0364, MGC75490, PGSF2" ENSG00000147255 "Immunoglobulin superfamily member 1" Q8N6C5 X 131273506-131578899 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Congenital hypothyroidism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "brain: 73.4;pituitary gland: 167.8" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Astrocytes: 3.9;Bipolar cells: 14.0;Breast glandular cells: 5.0;Horizontal cells: 3.3;Melanocytes: 3.6;Skeletal myocytes: 7.2" "Cancer enriched" "Detected in many" 8 "thyroid cancer: 65.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Hep G2: 47.6;SH-SY5Y: 31.2" "Region enhanced" "Detected in all" "hypothalamus: 144.0" "Low region specificity" "Detected in all" "HPA012732, HPA035582" Enhanced Approved Cytosol "Intracellular and membrane" NA NA 100000 "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 56: Bipolar cells - Visual perception" Cytosol "HPA012732: AB_2732404, HPA035582: AB_2674687" "unprognostic (1.40e-3)" "unprognostic (1.79e-1)" "unprognostic (4.11e-1)" "prognostic unfavorable (4.25e-8)" "unprognostic (1.01e-1)" "unprognostic (2.40e-2)" "unprognostic (1.90e-3)" "unprognostic (2.52e-3)" "unprognostic (8.03e-3)" "unprognostic (9.36e-2)" "unprognostic (5.65e-2)" "unprognostic (1.13e-1)" "unprognostic (1.38e-1)" "unprognostic (5.96e-2)" "unprognostic (1.66e-1)" "unprognostic (2.35e-1)" "unprognostic (5.13e-2)" 1.9 12.5 9.7 0.8 10.0 0.1 2.8 9.7 9.7 3.3 4.8 0.9 0.4 1.2 2.4 1.6 2.5 1.2 12.1 7.5 73.4 0.7 1.5 0.3 0.4 10.0 21.6 1.1 2.6 0.8 167.8 0.7 24.0 4.0 0.4 6.4 2.4 5.7 2.0 1.4 0.6 3.1 7.4 0.3 1.0 12.2 32.4 0.6 4.5 5.1 0.9 0.4 0.9 8.4 0.4 0.6 0.6 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.6 0.0 0.0 6.0 0.0 0.0 0.1 1.8 0.0 0.0 6.0 0.4 0.0 3.0 47.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.4 0.0 0.0 4.1 2.8 0.0 0.0 0.0 0.1 0.1 0.2 3.4 31.2 0.0 0.2 0.0 4.1 0.6 0.0 0.0 0.5 0.8 0.0 4.1 1.2 0.6 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 10.0 9.7 9.7 7.5 73.4 10.0 21.6 24.0 7.4 32.4 8.4 0.2 3.2 0.6 3.9 0.2 0.0 0.5 0.0 1.2 14.0 5.0 1.7 2.3 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.4 0.1 0.0 0.2 0.0 0.0 0.2 0.2 0.3 1.5 0.0 0.1 0.0 0.7 0.7 0.3 0.0 3.3 0.4 0.0 0.0 0.0 0.8 1.1 0.0 0.2 3.6 0.0 0.0 0.1 0.0 0.0 0.3 0.3 0.0 0.4 0.0 0.3 0.0 0.8 0.0 0.7 0.0 7.2 0.3 0.1 0.4 0.0 0.4 0.3 0.1 0.0 0.0 0.3 IGSF23 ENSG00000216588 "Immunoglobulin superfamily member 23" A1L1A6 19 44613563-44636781 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "intestine: 15.9;liver: 24.5" "Cell type enhanced" "Detected in some" "Cholangiocytes: 5.7;Early spermatids: 7.9;Hepatocytes: 11.9;Late spermatids: 9.9;Proximal enterocytes: 40.8" "Cancer enriched" "Detected in some" 10 "liver cancer: 12.4" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 5 "neutrophil: 2.4" "Lineage enriched" "Detected in single" 5 "granulocytes: 2.4" "Cell line enhanced" "Detected in some" "CACO-2: 10.5;Hep G2: 5.4;SiHa: 4.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA051811 Approved "Nucleoplasm,Cell Junctions" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" Nucleoplasm "Cell Junctions" "HPA051811: AB_2681621" "unprognostic (1.54e-1)" "unprognostic (1.84e-3)" "unprognostic (5.74e-2)" "unprognostic (1.53e-3)" "unprognostic (4.58e-2)" "unprognostic (1.11e-1)" "prognostic favorable (7.20e-6)" "unprognostic (7.35e-3)" "unprognostic (2.71e-1)" "unprognostic (3.27e-2)" "unprognostic (2.93e-3)" "unprognostic (1.52e-1)" "unprognostic (1.19e-8)" "unprognostic (1.26e-1)" "unprognostic (6.38e-2)" "unprognostic (9.17e-2)" "unprognostic (2.85e-1)" 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.0 0.2 14.7 0.1 0.7 0.0 0.0 0.1 0.5 0.1 0.1 0.4 24.5 0.2 0.0 0.4 0.4 0.0 3.7 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.2 0.0 15.9 0.0 0.1 0.0 0.1 1.3 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.3 0.6 0.0 0.3 0.0 0.0 0.5 0.3 0.5 0.0 0.4 10.5 0.3 0.0 0.7 0.3 0.2 0.2 0.0 0.0 0.2 0.2 0.0 0.0 0.2 5.4 0.0 0.0 0.1 0.3 0.0 0.6 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 4.7 1.6 0.0 0.0 0.2 0.0 1.9 0.3 0.4 0.4 0.0 0.9 0.0 0.0 0.1 0.2 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.4 0.4 0.2 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 7.9 0.3 0.0 0.1 0.0 0.0 0.4 0.5 0.2 0.0 0.0 0.1 0.0 0.0 0.7 11.9 0.0 0.0 0.4 1.2 0.0 0.3 0.0 9.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.4 1.2 0.0 0.0 0.0 40.8 3.1 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.1 1.3 0.0 IHO1 "CCDC36, CT74, FLJ25320, LELA1" ENSG00000173421 "Interactor of HORMAD1 1" Q8IYA8 3 49198428-49258106 "Predicted intracellular proteins" "Differentiation, DNA recombination, Meiosis, Oogenesis, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "choroid plexus: 7.5;testis: 26.5" "Cell type enhanced" "Detected in some" "Adipocytes: 1.7;Cardiomyocytes: 1.4;Fibroblasts: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 2.9;hTEC/SVTERT24-B: 9.2;LHCN-M2: 4.0;NTERA-2: 2.5;U-2197: 5.1;WM-115: 2.6" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA045690, HPA069534" Approved Approved Nucleoplasm NA NA "Cluster 17: Basophils - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA045690: AB_10964634, HPA069534: AB_2686146" "unprognostic (1.54e-1)" "unprognostic (9.53e-3)" "unprognostic (2.16e-1)" "unprognostic (5.05e-2)" "unprognostic (3.84e-2)" "unprognostic (1.86e-2)" "unprognostic (1.36e-2)" "unprognostic (1.49e-2)" "unprognostic (9.94e-3)" "unprognostic (2.62e-1)" "unprognostic (1.38e-1)" "unprognostic (1.36e-2)" "unprognostic (5.51e-4)" "unprognostic (3.11e-2)" "unprognostic (2.95e-1)" "unprognostic (3.59e-2)" "unprognostic (6.33e-2)" 3.2 1.4 0.2 0.3 0.2 0.2 1.8 0.9 0.5 1.3 7.5 1.1 0.2 1.2 0.4 0.4 1.3 0.7 1.1 0.4 0.0 0.3 0.1 0.5 0.3 0.1 0.3 3.8 0.2 0.1 0.2 0.9 0.1 0.4 0.1 0.7 0.3 0.5 0.9 0.6 0.4 1.0 0.1 0.5 0.3 26.5 0.5 0.1 1.0 0.8 0.1 0.8 0.6 0.1 0.0 0.1 0.0 0.0 1.9 2.2 0.0 2.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.4 0.0 0.1 1.7 0.0 9.2 0.0 0.0 1.2 0.0 0.0 0.1 4.0 0.0 0.0 0.1 2.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 5.1 0.0 0.0 0.0 0.0 0.0 0.1 2.6 0.7 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.9 0.5 0.4 0.0 0.1 0.3 0.1 0.1 0.5 0.1 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 IK "RED, RER" ENSG00000113141 "IK cytokine" Q13123 5 140647058-140662480 "Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 438.7;Endometrial ciliated cells: 510.8;Respiratory ciliated cells: 732.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048798 Supported Enhanced "Nuclear speckles" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 16: U-266 - Nucleosome" "Cluster 49: Ciliated cells - Cilium organization" "Nuclear speckles" "HPA048798: AB_2680525" "unprognostic (9.90e-2)" "prognostic favorable (1.29e-4)" "unprognostic (6.99e-2)" "unprognostic (1.49e-2)" "unprognostic (3.23e-1)" "unprognostic (2.44e-1)" "prognostic unfavorable (2.32e-7)" "unprognostic (1.19e-1)" "unprognostic (4.87e-2)" "unprognostic (4.37e-2)" "unprognostic (8.45e-2)" "unprognostic (2.81e-1)" "unprognostic (2.53e-3)" "unprognostic (3.76e-1)" "unprognostic (1.26e-1)" "unprognostic (3.26e-2)" "unprognostic (2.83e-1)" 73.9 64.0 53.4 68.7 56.6 135.4 66.9 64.4 70.8 70.0 62.3 76.1 55.4 73.9 74.4 77.0 143.5 53.4 74.2 54.2 68.6 67.0 68.6 69.5 89.9 60.6 60.6 78.8 48.3 74.3 55.8 64.9 59.9 60.3 70.3 90.4 65.2 66.2 136.5 73.4 67.9 64.6 57.0 71.6 60.5 107.7 57.6 114.0 72.6 83.0 96.0 69.6 68.1 62.3 119.1 132.5 114.4 163.2 125.7 106.4 133.4 139.0 146.7 151.6 153.2 184.1 133.4 138.9 167.4 145.4 172.3 120.9 168.2 190.1 175.4 198.1 136.6 130.4 213.2 117.8 129.6 214.6 136.9 117.2 124.4 151.5 136.8 112.0 132.7 114.9 144.3 121.1 137.3 110.0 184.1 216.8 74.5 100.3 134.2 145.5 160.7 141.4 117.7 109.2 103.6 112.3 171.5 155.6 172.9 97.9 181.3 171.8 141.2 126.2 87.9 106.2 167.8 181.8 294.1 188.4 141.8 162.4 94.5 353.1 136.5 240.3 188.3 157.1 168.9 197.4 202.7 194.3 139.0 191.5 212.7 199.1 229.4 198.8 193.0 131.2 284.4 247.0 53.4 56.6 64.4 70.8 54.2 68.6 60.6 60.6 59.9 57.0 57.6 62.3 110.7 163.5 134.9 10.1 102.8 46.1 86.4 127.5 61.5 75.3 40.0 57.7 126.7 80.1 177.1 86.5 29.2 115.2 139.9 69.2 121.3 106.4 438.7 510.8 124.9 91.4 34.1 137.6 7.6 99.6 99.6 82.6 50.0 107.2 132.2 68.0 54.3 74.7 70.6 53.8 8.2 66.4 97.6 56.8 58.8 55.0 98.2 80.2 56.9 8.4 107.4 116.1 151.4 8.5 7.4 110.1 67.3 83.8 76.9 50.5 80.4 120.8 732.0 97.3 72.3 96.0 115.7 311.3 145.0 65.3 45.5 132.8 128.5 93.0 65.5 66.9 IL10 "CSIF, IL-10, IL10A, TGIF" ENSG00000136634 "Interleukin 10" P22301 1 206767602-206774541 "Cancer-related genes, Candidate cardiovascular disease genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 6.7;lymphoid tissue: 7.7" "Group enriched" "Detected in some" 4 "Hofbauer cells: 28.3;Kupffer cells: 44.4;Langerhans cells: 35.5;Macrophages: 99.5" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in some" "thalamus: 3.5" "Immune cell enhanced" "Detected in some" "classical monocyte: 2.1;intermediate monocyte: 1.8" "Lineage enriched" "Detected in single" 6 "monocytes: 2.1" "Group enriched" "Detected in some" 11 "HMC-1: 14.6;U-266/70: 6.8" "Not detected" "Not detected" "Not detected" "Not detected" "CAB013120, HPA071391" Approved "Secreted to blood" NA NA 5670 "Cluster 7: Monocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" "CAB013120: , HPA071391: " "unprognostic (3.65e-2)" "unprognostic (1.14e-1)" "unprognostic (1.03e-2)" "unprognostic (8.71e-2)" "unprognostic (2.20e-1)" "unprognostic (2.63e-3)" "unprognostic (2.58e-1)" "unprognostic (1.54e-1)" "unprognostic (9.59e-2)" "unprognostic (4.26e-1)" "unprognostic (8.01e-2)" "unprognostic (4.00e-1)" "unprognostic (4.66e-4)" "unprognostic (7.11e-2)" "unprognostic (1.93e-2)" "unprognostic (2.73e-1)" "unprognostic (1.96e-2)" 6.7 2.1 0.1 7.7 0.1 3.2 0.7 0.2 0.7 0.8 0.9 1.0 0.8 0.3 0.1 1.5 1.4 3.5 1.1 0.2 0.5 0.2 1.6 1.5 5.7 0.7 0.4 0.4 0.1 0.2 0.4 1.9 0.6 0.4 1.3 0.0 0.2 0.7 0.0 0.1 1.1 3.1 0.5 4.9 0.8 0.8 3.5 2.9 0.2 1.2 2.0 2.9 0.3 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 0.2 0.2 0.0 0.0 0.0 0.0 2.1 0.0 0.0 1.8 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.3 0.4 0.1 0.1 0.2 0.7 0.2 0.5 0.7 0.4 0.6 0.5 3.5 1.2 0.5 0.0 1.9 0.0 5.6 1.0 0.4 0.0 0.0 0.2 0.2 0.3 0.3 0.0 1.3 0.0 0.0 0.1 1.3 0.0 0.0 0.0 6.9 0.1 0.2 1.9 0.0 0.4 0.0 0.0 0.1 0.8 1.1 0.2 1.3 0.0 0.7 0.5 28.3 0.0 0.0 0.0 0.0 44.4 35.5 2.9 0.0 99.5 1.8 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.4 0.9 0.3 0.0 0.0 0.0 0.4 0.0 0.9 0.8 0.0 0.2 0.7 1.1 0.1 12.9 0.0 0.0 0.4 IL10RA "CD210, CD210a, CDW210A, HIL-10R, IL10R" ENSG00000110324 "Interleukin 10 receptor subunit alpha" Q13651 11 117986370-118003037 "CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins" Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 63.6;lymphoid tissue: 73.7" "Cell type enhanced" "Detected in many" "dendritic cells: 87.5;Extravillous trophoblasts: 93.0;Kupffer cells: 190.7;Langerhans cells: 145.0;Macrophages: 128.6;monocytes: 175.7;NK-cells: 110.2;Plasma cells: 129.5;T-cells: 105.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 30.5;HDLM-2: 76.6;Karpas-707: 27.7;RPMI-8226: 35.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065647, HPA069086" Supported "Plasma membrane,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 2: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" Cytosol "HPA065647: , HPA069086: " "unprognostic (1.01e-2)" "unprognostic (2.07e-3)" "unprognostic (1.58e-2)" "unprognostic (7.08e-2)" "unprognostic (8.27e-2)" "prognostic favorable (4.47e-4)" "unprognostic (5.27e-2)" "unprognostic (4.84e-2)" "unprognostic (7.70e-3)" "unprognostic (5.94e-2)" "unprognostic (2.14e-2)" "unprognostic (3.83e-1)" "prognostic unfavorable (1.45e-5)" "unprognostic (1.82e-1)" "unprognostic (8.43e-3)" "unprognostic (2.19e-1)" "unprognostic (1.27e-1)" 13.9 8.9 4.7 39.8 4.9 63.6 6.1 4.4 7.0 5.6 4.9 12.0 8.0 3.5 2.7 6.4 5.2 17.9 5.3 4.2 5.9 4.1 13.1 23.8 51.7 6.9 5.1 3.1 2.4 2.6 3.6 14.2 5.5 4.7 14.5 0.5 5.2 3.2 1.7 3.2 24.8 10.4 6.0 73.7 9.2 1.9 5.3 16.9 4.2 3.3 32.4 20.7 3.7 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.5 0.2 0.0 0.7 0.0 0.5 0.0 0.0 76.6 0.0 0.2 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 5.6 27.7 0.0 0.0 0.4 6.0 0.1 0.0 0.0 0.0 0.0 35.5 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.1 0.0 2.2 0.0 0.0 0.0 0.1 0.0 5.6 1.0 8.0 0.0 11.4 0.0 3.3 48.9 2.4 52.8 68.6 38.3 12.6 51.0 62.1 44.7 6.2 17.9 33.3 3.4 70.2 58.6 17.3 88.7 84.1 4.7 4.9 4.4 7.0 4.2 5.9 6.9 5.1 5.5 6.0 5.3 7.5 2.2 6.4 16.0 0.3 52.8 5.7 0.4 0.0 5.7 0.1 1.0 1.9 2.7 0.0 1.3 0.0 0.0 1.3 87.5 0.5 0.0 0.2 0.1 0.4 0.5 4.9 0.0 9.3 0.8 0.8 93.0 2.3 6.6 0.7 12.6 0.0 3.6 1.4 60.4 0.0 1.2 0.0 0.0 190.7 145.0 0.5 0.3 128.6 17.8 22.5 175.7 0.4 110.2 0.0 0.6 0.1 0.1 0.0 129.5 0.0 0.0 1.0 1.5 0.1 0.0 1.6 2.7 0.1 0.3 1.2 4.1 3.3 105.5 0.0 0.7 0.4 IL15RA "CD215, IL-15RA" ENSG00000134470 "Interleukin 15 receptor subunit alpha" Q13261 10 5943639-5978187 "CD markers, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ductal cells: 39.1;Exocrine glandular cells: 55.2;Fibroblasts: 37.6;Hepatic stellate cells: 36.0;monocytes: 55.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 70.8;EFO-21: 41.3;HDLM-2: 78.5;HHSteC: 42.7" "Low region specificity" "Detected in all" "Region enriched" "Detected in single" 8 "cerebellum: 7.1" CAB026215 Approved "Secreted to blood" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 19: Lung - Lung function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 50: Fibroblasts - ECM organization" "CAB026215: " "unprognostic (2.86e-2)" "unprognostic (8.41e-2)" "unprognostic (6.13e-2)" "unprognostic (4.45e-2)" "unprognostic (7.87e-2)" "unprognostic (5.49e-2)" "prognostic unfavorable (2.67e-6)" "unprognostic (5.09e-3)" "unprognostic (1.82e-2)" "unprognostic (1.69e-1)" "prognostic unfavorable (5.35e-4)" "unprognostic (6.18e-3)" "prognostic unfavorable (1.27e-12)" "unprognostic (4.43e-2)" "unprognostic (4.69e-2)" "unprognostic (4.08e-2)" "unprognostic (5.75e-2)" 19.3 7.5 3.3 20.4 3.7 11.7 18.3 3.0 4.6 21.5 3.6 12.3 16.2 15.0 4.6 11.5 18.8 23.2 17.8 2.8 4.4 14.1 19.5 44.5 21.3 5.7 3.9 3.7 11.5 2.2 4.6 16.1 4.6 10.4 10.9 0.3 8.0 5.3 7.1 11.2 15.7 12.1 4.8 15.1 16.3 3.2 4.6 5.7 12.1 10.2 11.6 25.7 12.7 3.5 16.8 2.4 0.0 0.7 21.5 4.9 4.3 8.6 18.4 10.7 11.4 0.3 70.8 1.9 41.3 16.0 6.0 15.6 2.0 12.1 2.4 78.5 3.5 2.0 4.9 1.2 42.7 0.9 0.6 4.1 4.2 6.0 0.2 4.4 29.1 1.3 20.5 23.5 0.3 9.3 3.6 8.9 0.4 6.7 6.8 10.0 0.0 13.4 2.8 1.3 0.1 0.1 12.9 1.4 0.6 0.2 6.1 8.0 10.8 0.5 1.3 30.1 11.2 20.5 6.2 0.4 4.9 12.4 0.7 10.2 26.0 6.6 18.9 32.8 29.1 10.8 14.7 19.7 7.1 6.4 6.1 11.0 7.5 11.5 21.0 0.1 17.7 12.8 3.3 3.7 3.0 4.6 2.8 4.4 5.7 3.9 4.6 4.8 4.6 3.5 25.2 6.4 5.0 1.3 6.0 5.7 5.7 9.9 4.6 0.0 4.4 3.0 5.8 22.8 3.3 0.0 0.0 0.6 4.2 5.8 0.0 39.1 1.7 5.1 23.0 21.0 5.4 19.8 3.3 55.2 1.6 37.6 9.7 6.7 3.8 0.1 36.0 8.7 6.6 0.0 0.9 6.8 2.0 14.7 5.5 2.1 5.0 7.3 3.6 12.2 55.0 0.0 4.1 1.0 0.3 35.5 13.3 0.7 22.2 20.1 9.3 0.1 3.4 0.0 0.0 7.1 6.4 0.2 0.4 4.6 6.5 0.1 7.8 0.0 9.3 6.8 IL17B "IL-17B, IL-20, MGC138900, MGC138901, NIRF, ZCYTO7" ENSG00000127743 "Interleukin 17B" Q9UHF5 5 149371324-149404202 "Cancer-related genes, Predicted secreted proteins" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 44.8;Peritubular cells: 13.2;Sertoli cells: 26.3;Smooth muscle cells: 7.6;Theca cells: 9.9" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 12 "basophil: 1.2" "Lineage enriched" "Detected in single" 12 "granulocytes: 1.2" "Cell line enhanced" "Detected in some" "HEL: 1.3;Karpas-707: 1.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA042441 Uncertain "Secreted to blood" NA NA 75000 "Cluster 46: Basophils - DNA binding" "Cluster 71: Testis - DNA repair" "Cluster 36: HEL - Hemostasis" "Cluster 48: Smooth muscle cells - ECM organization" "HPA042441: AB_10797014" "unprognostic (2.83e-4)" "unprognostic (2.71e-2)" "unprognostic (4.90e-3)" "unprognostic (9.22e-2)" "unprognostic (7.43e-2)" "unprognostic (5.03e-2)" "unprognostic (9.62e-3)" "unprognostic (3.00e-1)" "unprognostic (1.80e-1)" "unprognostic (6.54e-2)" "unprognostic (9.30e-3)" "unprognostic (3.22e-1)" "unprognostic (6.98e-8)" "unprognostic (2.66e-1)" "unprognostic (1.53e-1)" "unprognostic (6.47e-2)" "unprognostic (1.10e-1)" 1.4 2.2 0.0 1.0 0.0 0.2 2.9 0.5 0.1 3.2 0.0 3.1 0.3 4.3 0.0 1.5 1.1 0.4 1.1 0.0 0.0 0.7 0.0 0.4 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.1 0.1 2.4 0.1 0.4 2.8 2.1 0.3 0.9 1.3 2.2 0.0 0.6 0.8 3.7 0.0 0.0 0.1 0.2 0.0 1.4 0.8 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.0 1.3 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 1.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.6 0.1 0.0 0.0 0.0 0.8 44.8 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.3 0.0 0.0 0.1 0.2 0.6 1.3 0.0 0.0 0.0 0.1 0.4 0.0 0.1 0.0 0.1 0.0 0.0 1.0 1.1 3.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.2 0.0 0.0 0.0 0.0 0.0 0.0 26.3 0.6 7.6 0.1 0.1 0.0 0.3 0.0 0.0 9.9 0.0 0.1 IL17RB "CRL4, EVI27, IL17BR, IL17RH1" ENSG00000056736 "Interleukin 17 receptor B" Q9NRM6 3 53846568-53865794 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.9;kidney: 59.8;liver: 33.3" "Cell type enhanced" "Detected in many" "Astrocytes: 48.3;Enteroendocrine cells: 29.2;Oligodendrocyte precursor cells: 37.7;Proximal tubular cells: 78.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "CACO-2: 20.2;Hep G2: 59.5;OE19: 46.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA005482 Enhanced Approved "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 7: Kidney - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Plasma membrane" "HPA005482: AB_1234567" "unprognostic (1.85e-3)" "unprognostic (4.22e-3)" "unprognostic (1.60e-3)" "unprognostic (2.86e-2)" "unprognostic (1.42e-2)" "unprognostic (6.20e-3)" "unprognostic (1.62e-2)" "unprognostic (6.09e-3)" "unprognostic (1.30e-1)" "unprognostic (5.41e-2)" "unprognostic (4.75e-2)" "unprognostic (4.27e-2)" "prognostic favorable (6.61e-4)" "unprognostic (8.10e-2)" "unprognostic (6.97e-2)" "unprognostic (5.29e-1)" "unprognostic (7.15e-3)" 0.9 2.0 20.2 2.3 21.4 0.5 5.7 22.7 28.9 18.1 16.6 6.8 5.8 5.1 0.7 1.7 3.3 2.4 2.7 19.4 20.2 59.8 33.3 3.8 2.5 18.7 19.9 1.5 7.8 1.1 4.2 0.9 19.0 2.4 6.9 4.8 4.9 0.6 1.3 2.2 5.9 0.8 18.9 1.2 3.6 2.5 23.2 0.3 2.9 0.2 0.7 0.8 1.3 23.6 1.5 3.1 4.5 3.4 0.1 0.0 7.1 3.1 0.1 0.1 0.0 20.2 1.4 4.6 1.0 1.0 1.7 0.8 12.2 0.0 0.0 1.6 3.5 6.0 6.1 59.5 0.0 5.6 3.2 0.0 0.0 0.0 0.0 3.8 0.0 1.6 4.9 2.1 0.1 4.2 0.9 2.3 12.1 46.2 2.6 1.7 1.9 5.3 1.4 5.3 6.4 3.7 10.1 2.4 1.9 3.3 9.2 2.0 2.5 3.0 3.3 2.6 3.9 4.7 5.6 2.9 2.7 3.3 1.7 1.3 0.2 0.0 0.2 0.2 0.1 0.1 0.6 0.2 0.0 0.2 0.2 0.2 0.1 0.1 0.0 0.3 0.9 0.1 20.2 21.4 22.7 28.9 19.4 20.2 18.7 19.9 19.0 18.9 23.2 23.6 0.2 0.0 4.1 48.3 0.2 0.3 2.0 0.0 0.0 0.1 8.2 4.4 4.1 17.2 1.3 0.0 0.0 1.4 0.3 4.3 9.8 4.8 1.0 0.5 1.0 0.2 29.2 0.0 0.5 1.6 1.0 0.6 4.6 1.7 2.5 0.4 0.4 13.1 0.1 0.0 2.5 8.7 2.0 0.0 1.1 0.7 1.2 1.2 0.0 1.9 0.0 4.4 0.0 37.7 4.3 1.8 3.0 0.4 0.0 4.4 2.9 78.0 0.0 0.1 0.0 0.3 0.5 0.4 1.0 0.0 0.1 0.4 0.9 0.0 10.2 0.6 IL19 "IL-10C, IL-19, MDA1, NG.1, ZMDA1" ENSG00000142224 "Interleukin 19" Q9UHD0 1 206770764-206842979 "Predicted secreted proteins" Apoptosis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "cervix: 20.0;salivary gland: 6.9" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 11.3;Breast glandular cells: 3.2;Club cells: 9.6;Endometrial ciliated cells: 2.9;Glandular and luminal cells: 5.2;Ionocytes: 4.1" "Cancer enhanced" "Detected in some" "endometrial cancer: 1.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "BJ hTERT+: 9.1" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 172000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "unprognostic (6.21e-2)" "unprognostic (3.84e-2)" "unprognostic (3.55e-1)" "unprognostic (2.17e-2)" "unprognostic (2.48e-5)" "unprognostic (1.07e-1)" "unprognostic (8.72e-3)" "unprognostic (8.42e-2)" "unprognostic (2.04e-3)" "unprognostic (9.17e-2)" "unprognostic (7.20e-2)" "unprognostic (4.91e-2)" "unprognostic (2.78e-1)" 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.2 20.0 0.0 0.1 0.0 0.3 0.0 1.8 0.1 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.2 0.0 0.1 0.1 6.9 0.3 0.0 0.1 0.0 0.1 0.0 0.1 0.4 0.2 0.3 0.2 0.1 0.0 0.4 1.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.2 0.1 0.0 11.3 0.0 0.0 3.2 0.0 0.1 0.0 9.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 2.9 0.7 0.0 0.0 0.0 0.1 1.6 0.0 0.1 0.0 5.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 4.1 0.0 1.2 0.2 0.0 0.9 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 IL3RA CD123 ENSG00000185291 "Interleukin 3 receptor subunit alpha" P26951 X 1336616-1382689 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 79.0;dendritic cells: 137.5;Endothelial cells: 83.2;Langerhans cells: 47.6;monocytes: 72.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 2665.0" "Lineage enriched" "Detected in all" 4 "granulocytes: 2665.0" "Cell line enhanced" "Detected in many" "HDLM-2: 128.8;NB-4: 24.9;RPMI-8226: 54.1" "HPA003539, CAB018374" Uncertain NA NA "Cluster 38: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 44: HDLM-2 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "CAB018374: AB_2233620, HPA003539: AB_1078438" "prognostic favorable (9.78e-4)" "prognostic favorable (4.27e-4)" "unprognostic (8.13e-2)" "unprognostic (9.32e-2)" "unprognostic (2.09e-1)" "unprognostic (1.29e-3)" "unprognostic (1.32e-1)" "unprognostic (1.67e-1)" "unprognostic (1.38e-1)" "unprognostic (3.73e-2)" "unprognostic (5.77e-3)" "unprognostic (1.43e-1)" "unprognostic (1.50e-3)" "unprognostic (9.41e-2)" "unprognostic (2.85e-3)" "unprognostic (2.49e-1)" "unprognostic (1.46e-1)" 25.2 2.9 7.1 15.8 13.6 25.0 20.6 16.1 11.7 6.4 0.2 8.1 5.5 8.7 1.6 5.4 8.0 11.3 13.0 5.9 8.1 9.2 1.8 25.0 25.1 11.7 10.6 8.8 5.4 3.4 2.8 6.2 11.1 7.0 6.6 22.0 9.5 3.2 12.1 12.7 9.2 12.3 7.5 11.1 6.9 3.5 10.1 4.4 10.3 8.6 13.0 12.4 6.3 20.5 0.2 9.4 3.6 1.3 0.1 0.0 1.1 1.2 0.3 0.0 0.1 0.9 1.5 1.2 7.2 0.2 0.6 9.6 0.0 0.0 0.0 128.8 3.9 0.6 2.1 0.4 0.0 0.8 15.6 0.0 0.0 0.0 0.0 4.1 8.2 0.9 0.3 6.1 0.0 1.4 0.7 24.9 3.1 0.8 0.5 1.4 4.2 54.1 0.0 1.4 0.6 0.4 0.6 0.3 2.8 1.8 1.2 17.8 0.4 0.5 1.5 0.5 0.3 12.5 3.9 1.1 9.8 2.8 0.1 2665.0 5.6 83.9 0.6 31.7 1.0 2.5 0.9 0.5 14.9 8.9 0.7 0.7 4.6 14.2 42.5 628.5 0.5 12.0 7.1 13.6 16.1 11.7 5.9 8.1 11.7 10.6 11.1 7.5 10.1 20.5 79.0 3.2 1.8 11.8 6.8 5.9 0.7 0.9 1.2 2.3 0.5 0.9 2.2 1.5 1.0 0.0 10.4 0.1 137.5 4.7 0.0 0.4 0.2 2.7 1.4 83.2 0.0 3.0 7.3 0.2 0.1 4.3 0.5 1.5 11.4 0.4 24.3 0.7 4.6 0.0 14.3 7.3 0.0 2.8 47.6 0.1 0.3 32.9 8.8 13.1 72.6 0.6 1.0 6.0 18.2 0.1 3.4 0.7 4.0 0.7 0.2 0.0 0.4 3.2 0.0 3.6 3.2 0.1 0.7 0.7 5.5 0.3 1.6 1.3 0.6 2.1 ILDR1 "DFNB42, MGC50831" ENSG00000145103 "Immunoglobulin like domain containing receptor 1" Q86SU0 3 121987323-122022247 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 15.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 12.8;Club cells: 14.7;Collecting duct cells: 20.2;Cytotrophoblasts: 16.6;Distal enterocytes: 17.5;Glandular and luminal cells: 13.5;Respiratory ciliated cells: 13.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.7" "Lineage enriched" "Detected in single" 4 "B-cells: 1.7" "Cell line enhanced" "Detected in some" "CAPAN-2: 6.3;HDLM-2: 8.2;MCF7: 5.1;RT4: 7.5;T-47d: 5.3;U-266/70: 6.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA018207 Approved "Intracellular and membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 37: Intestine - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA018207: AB_1851742" "unprognostic (2.69e-1)" "unprognostic (1.28e-2)" "unprognostic (9.24e-2)" "unprognostic (4.46e-3)" "unprognostic (9.73e-2)" "unprognostic (1.24e-1)" "unprognostic (1.65e-2)" "unprognostic (2.80e-2)" "unprognostic (2.00e-1)" "unprognostic (2.04e-1)" "unprognostic (7.78e-2)" "unprognostic (2.37e-1)" "prognostic favorable (5.79e-9)" "unprognostic (1.44e-2)" "unprognostic (1.18e-1)" "unprognostic (3.25e-3)" "unprognostic (2.21e-2)" 0.0 0.7 0.2 1.3 0.1 0.3 2.9 0.2 0.3 11.7 0.1 8.2 3.3 1.0 12.8 3.8 5.1 3.3 0.0 0.1 0.0 6.5 0.2 2.9 1.1 0.1 0.1 0.0 6.7 15.7 2.4 1.8 0.1 6.9 7.2 0.2 8.0 10.6 0.1 1.2 2.4 0.3 0.0 0.6 0.8 0.6 0.1 0.8 7.3 0.0 2.2 2.2 1.1 0.1 2.9 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.2 6.3 1.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 8.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 5.1 0.0 0.1 0.0 1.2 0.0 0.0 0.0 2.4 2.8 7.5 0.2 0.0 0.0 0.7 0.0 0.1 5.3 0.0 0.0 0.0 0.0 0.0 0.0 6.1 1.4 1.1 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.1 0.0 1.7 0.0 0.0 0.2 1.1 0.1 0.0 0.2 0.0 0.0 0.0 0.4 0.1 0.2 0.1 0.2 0.3 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 12.8 7.4 0.3 1.3 0.0 0.8 7.5 0.0 0.0 4.2 2.4 0.7 4.3 14.7 20.2 0.0 16.6 0.1 17.5 1.9 7.5 0.2 6.3 1.6 0.1 3.5 0.0 0.5 3.7 0.5 0.1 1.1 13.5 0.0 0.2 0.0 0.1 1.2 0.0 0.5 7.9 8.2 0.6 0.0 0.0 0.0 0.3 1.8 1.9 0.0 0.0 0.0 0.0 0.2 2.6 8.9 0.0 2.1 2.2 2.5 2.1 13.7 0.0 0.0 0.0 0.6 0.0 0.1 5.9 0.6 5.1 0.1 0.0 7.8 3.5 ILVBL "209L8, AHAS, FLJ39061, HACL1L, ILV2H, MGC1269, MGC19535" ENSG00000105135 "IlvB acetolactate synthase like" A1L0T0 19 15114984-15125786 "Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 148.2;Syncytiotrophoblasts: 253.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067682 Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Golgi apparatus, Vesicles" "HPA067682: AB_2685885" "unprognostic (5.68e-2)" "unprognostic (1.86e-1)" "unprognostic (3.72e-2)" "prognostic unfavorable (1.52e-4)" "unprognostic (8.59e-2)" "unprognostic (1.53e-1)" "unprognostic (4.04e-2)" "unprognostic (2.53e-1)" "unprognostic (3.83e-1)" "unprognostic (5.60e-2)" "unprognostic (1.77e-2)" "unprognostic (2.61e-1)" "prognostic favorable (1.91e-8)" "unprognostic (4.65e-2)" "unprognostic (1.68e-1)" "unprognostic (1.40e-1)" "unprognostic (2.40e-1)" 29.7 45.5 22.7 13.9 27.5 15.5 27.5 30.9 25.1 29.7 32.8 46.2 50.1 24.3 14.4 40.9 22.6 25.5 73.7 21.4 25.5 41.6 56.8 19.2 15.5 29.2 25.3 28.3 42.5 65.8 34.4 19.2 26.3 24.2 18.6 13.8 27.7 23.2 18.7 43.4 43.7 13.7 24.8 17.6 41.1 25.5 25.2 10.5 48.0 25.0 10.6 28.5 30.6 32.3 68.8 41.0 34.4 40.7 43.8 29.7 39.6 31.6 42.2 37.2 47.5 65.5 162.1 29.7 61.1 34.2 22.3 50.6 20.9 38.5 10.8 27.5 41.1 43.7 41.3 72.4 70.1 37.2 37.0 44.6 43.9 21.7 28.3 30.4 35.0 29.6 17.9 37.6 29.3 159.0 24.9 29.6 31.9 54.9 58.8 36.0 31.1 46.5 32.3 33.6 28.4 38.3 18.8 81.2 62.1 13.2 37.2 31.2 37.7 55.9 30.7 71.0 45.1 26.1 29.2 15.1 35.9 35.8 43.1 22.7 22.2 5.5 21.1 31.8 24.0 11.9 17.7 22.0 26.3 12.9 22.9 23.6 2.5 23.7 30.3 19.1 20.2 23.3 22.7 27.5 30.9 25.1 21.4 25.5 29.2 25.3 26.3 24.8 25.2 32.3 28.0 25.6 11.7 18.3 12.7 12.7 26.8 53.8 22.2 95.3 18.0 14.9 36.1 62.9 43.0 25.8 27.1 84.2 15.8 67.8 19.6 48.4 6.2 9.9 13.4 23.2 44.4 12.6 4.9 50.6 148.2 21.4 40.2 13.0 11.4 29.0 26.7 59.3 43.2 18.5 8.3 60.6 28.5 12.1 9.5 6.5 25.7 15.8 83.6 5.6 6.8 48.0 7.2 9.0 15.7 32.3 68.4 19.9 17.2 18.6 123.0 50.4 26.1 36.8 19.7 14.7 21.2 20.3 20.8 25.0 16.2 253.4 11.8 48.2 73.2 23.4 IMMP1L "FLJ25059, IMMP1" ENSG00000148950 "Inner mitochondrial membrane peptidase subunit 1" Q96LU5 11 31432401-31509645 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038372, HPA058308" Approved Enhanced Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA038372: AB_10669643, HPA058308: AB_2732620" "unprognostic (2.39e-1)" "unprognostic (1.20e-2)" "unprognostic (1.12e-1)" "unprognostic (6.17e-2)" "unprognostic (9.67e-2)" "unprognostic (2.08e-2)" "prognostic unfavorable (7.97e-4)" "unprognostic (7.59e-2)" "unprognostic (4.66e-3)" "unprognostic (5.15e-3)" "prognostic favorable (6.72e-4)" "unprognostic (1.97e-1)" "unprognostic (1.07e-2)" "unprognostic (4.66e-1)" "unprognostic (4.52e-2)" "unprognostic (1.37e-2)" "unprognostic (1.04e-3)" 11.7 15.6 42.8 6.4 43.7 11.1 19.3 45.5 66.4 13.5 41.8 12.7 8.6 11.5 29.8 11.7 10.4 5.1 26.2 42.8 42.3 27.2 18.6 8.9 9.5 42.4 42.0 17.5 16.4 17.9 23.3 6.9 42.3 14.3 10.0 37.7 11.8 14.1 50.0 12.5 9.5 10.7 42.9 10.8 15.1 16.7 43.0 24.8 13.2 42.1 13.1 10.9 12.6 43.5 22.9 26.9 95.6 21.0 14.9 9.9 15.3 19.9 8.7 16.2 11.7 21.0 17.5 20.7 18.7 15.9 32.5 25.8 37.6 28.8 23.8 24.9 52.6 29.4 45.5 32.3 15.8 29.6 19.9 8.0 27.1 8.7 19.2 29.5 17.5 48.8 38.0 23.2 15.9 28.2 48.5 48.9 15.8 114.6 26.3 41.1 72.2 20.6 54.6 26.2 22.5 27.0 32.5 11.6 32.5 61.9 37.1 35.1 2.6 15.3 27.2 16.2 42.2 17.2 58.2 47.5 24.9 24.9 18.5 21.9 3.0 32.2 28.9 3.4 26.3 34.1 25.3 29.5 8.1 32.1 32.0 39.8 0.8 37.3 3.0 40.2 35.4 13.6 42.8 43.7 45.5 66.4 42.8 42.3 42.4 42.0 42.3 42.9 43.0 43.5 29.2 35.3 14.6 30.7 22.4 18.2 26.8 60.5 12.0 30.6 44.6 55.1 56.8 18.6 26.8 60.7 33.3 36.3 17.6 21.7 119.3 17.0 39.8 30.2 16.9 19.4 56.5 47.4 40.6 24.5 32.5 19.7 20.9 33.8 22.7 22.7 18.2 45.0 21.3 43.7 48.0 30.6 52.9 7.7 11.4 10.5 13.4 9.4 8.8 24.4 10.3 85.3 30.9 51.3 60.7 15.8 26.7 20.7 22.0 26.0 18.6 98.4 28.9 38.5 32.9 19.1 51.0 61.6 23.0 19.6 27.3 23.7 24.2 16.2 34.7 26.2 INCA1 ENSG00000196388 "Inhibitor of CDK, cyclin A1 interacting protein 1" Q0VD86 17 4988130-4997610 "Predicted intracellular proteins" "Protein kinase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "testis: 47.8" "Group enriched" "Detected in many" 19 "Early spermatids: 130.0;Late spermatids: 306.6;Spermatocytes: 211.3;Spermatogonia: 87.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Daudi: 23.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044359, HPA052401" Uncertain Approved "Nucleoplasm,Nuclear bodies" No No "Cluster 7: Monocytes - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoplasm, Nuclear bodies" "HPA044359: AB_10794289, HPA052401: AB_2681816" "unprognostic (1.78e-2)" "unprognostic (9.38e-2)" "unprognostic (4.08e-2)" "unprognostic (9.81e-2)" "unprognostic (1.22e-2)" "unprognostic (1.02e-2)" "unprognostic (9.54e-3)" "unprognostic (7.88e-2)" "unprognostic (2.68e-1)" "unprognostic (2.66e-2)" "prognostic favorable (3.61e-5)" "unprognostic (3.14e-2)" "unprognostic (1.68e-1)" "unprognostic (9.54e-2)" "unprognostic (2.04e-1)" "unprognostic (1.17e-1)" "unprognostic (1.05e-1)" 2.9 3.7 3.2 6.3 3.4 1.6 2.1 4.3 4.2 3.6 2.0 3.3 10.8 5.2 0.8 5.1 3.2 7.1 6.6 3.0 3.8 4.0 3.8 4.6 8.5 4.3 3.4 8.1 3.9 1.6 2.2 3.0 4.5 4.5 1.2 4.4 5.7 1.7 10.6 8.0 7.9 2.2 3.6 7.3 5.0 47.8 4.3 0.4 8.0 4.8 0.4 2.7 2.4 3.9 5.0 5.6 3.9 3.7 2.6 1.0 4.7 5.3 0.5 1.4 1.5 4.0 5.9 23.9 3.5 1.4 4.6 14.0 0.7 0.3 0.8 10.0 5.9 5.2 7.6 2.7 1.8 0.8 12.2 1.5 0.0 0.8 0.4 8.5 0.5 8.4 6.6 10.9 1.0 2.6 7.4 1.7 1.7 2.3 1.5 9.0 2.0 2.2 0.9 1.6 11.7 3.5 2.6 3.4 3.1 4.1 7.0 1.1 10.8 4.9 1.8 4.7 4.1 1.8 1.0 1.1 4.8 12.6 2.5 0.2 0.8 0.0 0.2 1.5 0.6 0.4 0.4 0.5 0.3 0.2 0.7 0.6 0.2 0.0 1.2 0.4 0.2 0.2 3.2 3.4 4.3 4.2 3.0 3.8 4.3 3.4 4.5 3.6 4.3 3.9 1.0 0.0 1.1 1.0 0.6 1.1 1.5 1.2 0.6 0.5 0.9 0.8 1.0 1.5 1.2 3.7 2.1 0.6 0.1 9.3 0.0 0.7 130.0 0.6 0.8 1.3 0.0 2.7 0.8 1.6 0.7 1.3 1.5 0.6 4.5 2.5 0.7 1.4 1.2 0.0 0.9 2.0 2.0 0.0 1.5 306.6 7.2 1.1 1.8 1.0 0.7 6.1 0.0 1.0 1.1 1.2 9.3 1.2 0.1 0.4 5.2 2.2 1.5 0.8 6.6 2.0 1.9 211.3 87.1 0.3 0.9 0.8 0.2 0.7 2.9 0.8 ING2 "ING1L, p33ING2" ENSG00000168556 "Inhibitor of growth family member 2" Q9H160 4 183505058-183512429 "Predicted intracellular proteins" "Growth regulation, Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019486, HPA021517" Supported Supported Nucleoplasm NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 2: Karpas-707 - Immune response" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA019486: AB_1851780, HPA021517: AB_10601914" "prognostic favorable (5.43e-4)" "unprognostic (1.04e-1)" "unprognostic (2.81e-1)" "unprognostic (3.74e-2)" "unprognostic (3.89e-3)" "unprognostic (4.56e-2)" "prognostic unfavorable (8.87e-4)" "unprognostic (7.47e-3)" "unprognostic (2.27e-1)" "unprognostic (1.09e-3)" "unprognostic (1.65e-2)" "unprognostic (1.97e-1)" "unprognostic (2.30e-3)" "unprognostic (6.19e-2)" "unprognostic (4.43e-1)" "unprognostic (5.52e-2)" "unprognostic (7.82e-2)" 9.5 42.3 5.2 5.2 5.8 21.7 8.7 6.8 6.8 7.2 5.5 9.4 10.6 5.2 10.2 14.6 8.8 8.9 7.5 5.0 9.6 12.2 10.5 8.6 5.9 6.4 6.4 37.4 15.8 6.1 23.3 6.1 6.0 8.7 6.7 8.6 10.7 4.5 26.1 12.1 14.3 4.6 4.6 9.1 11.5 33.3 8.0 12.5 9.3 14.8 6.7 11.4 9.9 5.3 19.1 11.4 15.5 12.3 28.1 16.4 12.7 20.1 17.4 15.6 13.3 10.4 20.2 13.5 5.2 14.7 12.7 8.3 10.4 15.6 19.8 10.4 7.6 23.4 11.4 13.5 8.5 19.3 25.1 12.7 14.3 17.0 7.1 12.8 7.5 13.0 13.2 49.8 11.5 18.8 24.7 19.6 12.5 5.5 11.1 10.3 8.6 22.5 18.8 8.7 15.3 11.5 13.3 17.6 5.3 10.0 8.3 13.9 6.4 10.5 16.5 7.2 13.0 10.7 8.6 9.1 19.3 14.3 7.6 15.2 6.3 19.7 3.2 6.6 5.0 11.9 6.3 5.7 7.8 8.4 8.8 7.6 6.4 3.8 8.5 7.6 5.4 3.7 5.2 5.8 6.8 6.8 5.0 9.6 6.4 6.4 6.0 4.6 8.0 5.3 18.7 6.4 21.0 6.2 20.1 49.3 20.5 20.7 105.9 25.7 36.3 41.8 12.1 25.8 18.2 16.5 12.5 26.1 18.8 32.7 74.3 20.9 68.4 93.0 26.3 21.7 18.6 26.7 7.1 34.9 94.9 29.1 11.7 82.9 40.0 85.4 15.4 24.1 30.0 25.2 5.3 24.2 16.2 24.2 43.3 35.2 82.6 27.3 26.6 1.0 13.9 40.5 6.2 3.5 5.1 33.3 28.3 53.8 19.5 34.2 112.9 47.8 39.8 23.6 19.7 23.7 28.0 95.3 74.9 71.6 46.2 21.2 25.6 50.4 23.0 39.3 INO80C "C18orf37, FLJ38183, hIes6, IES6" ENSG00000153391 "INO80 complex subunit C" Q6PI98 18 35452230-35497979 "Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA recombination, DNA repair, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 184.7;Pancreatic endocrine cells: 165.1;Spermatocytes: 209.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049060 Approved Approved "Nucleoli fibrillar center" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 77: Retina - Visual perception" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoli fibrillar center" "HPA049060: AB_2680617" "unprognostic (3.40e-1)" "prognostic favorable (3.58e-4)" "unprognostic (2.29e-1)" "prognostic unfavorable (2.62e-5)" "unprognostic (5.56e-2)" "unprognostic (9.68e-2)" "unprognostic (1.72e-3)" "unprognostic (2.03e-1)" "unprognostic (3.32e-3)" "unprognostic (2.08e-3)" "unprognostic (2.61e-1)" "unprognostic (6.94e-3)" "unprognostic (1.18e-1)" "unprognostic (5.82e-2)" "unprognostic (1.44e-2)" "unprognostic (5.14e-3)" "unprognostic (5.38e-2)" 18.0 17.4 23.2 14.5 24.4 46.2 16.0 24.9 23.7 18.4 30.9 21.1 18.4 12.0 13.6 45.7 13.7 13.0 25.6 23.2 31.1 21.8 19.2 17.5 26.2 22.2 23.1 9.8 13.3 8.0 29.2 20.7 24.2 13.9 21.8 33.6 20.7 9.2 42.4 40.5 18.6 11.0 21.0 31.2 30.4 92.2 31.5 21.9 15.2 30.7 29.2 21.4 20.8 23.6 46.5 30.1 27.1 14.9 9.5 23.6 29.7 17.5 13.2 27.3 36.5 37.5 38.7 77.4 36.6 11.9 41.6 31.3 52.4 112.7 24.8 22.9 28.3 97.8 36.0 40.7 21.0 57.4 60.1 10.7 31.9 70.7 37.9 33.7 80.0 32.3 30.4 27.8 44.7 49.3 36.4 48.5 34.6 32.2 18.0 28.5 19.2 26.5 58.4 58.9 37.3 25.8 27.9 31.6 23.4 41.8 31.5 46.1 51.5 30.9 13.5 24.0 32.3 24.1 28.4 137.8 25.2 52.7 19.2 21.3 14.8 35.6 12.3 20.6 12.2 24.9 17.0 16.3 22.2 17.8 17.2 14.2 23.0 12.4 18.3 33.5 21.7 11.8 23.2 24.4 24.9 23.7 23.2 31.1 22.2 23.1 24.2 21.0 31.5 23.6 40.2 6.4 10.1 5.9 19.5 24.0 22.1 72.3 18.8 4.4 16.3 15.2 17.8 18.6 31.6 12.9 4.2 59.8 14.0 81.4 31.3 43.9 184.7 16.7 6.6 30.5 15.0 29.0 15.6 40.0 105.1 14.1 41.8 14.4 20.3 9.0 22.1 16.6 52.2 5.0 11.3 20.4 36.7 17.9 15.0 49.6 6.2 16.4 23.2 6.5 14.1 22.8 14.4 9.0 10.9 165.1 76.0 7.2 26.4 20.7 48.8 80.9 31.5 14.1 0.0 18.5 15.6 209.0 40.3 35.3 39.9 73.2 16.4 11.9 35.9 34.7 INSIG2 ENSG00000125629 "Insulin induced gene 2" Q9Y5U4 2 118088452-118110997 "Predicted membrane proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB033861 Uncertain NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "CAB033861: AB_2249149" "unprognostic (3.84e-3)" "unprognostic (4.54e-3)" "unprognostic (1.84e-1)" "unprognostic (7.00e-2)" "unprognostic (6.24e-2)" "prognostic unfavorable (7.10e-4)" "unprognostic (1.80e-1)" "unprognostic (7.30e-2)" "unprognostic (7.41e-2)" "unprognostic (2.37e-1)" "prognostic unfavorable (2.19e-6)" "unprognostic (2.40e-1)" "prognostic unfavorable (4.11e-6)" "unprognostic (1.40e-1)" "unprognostic (2.65e-1)" "unprognostic (1.42e-1)" "unprognostic (3.75e-2)" 10.4 6.2 5.0 5.7 5.4 3.8 8.5 7.3 6.3 8.7 7.2 8.8 9.6 9.4 8.9 6.6 7.0 8.2 8.5 7.1 5.1 12.3 28.0 10.3 7.3 5.4 5.8 10.3 11.7 12.4 7.0 9.0 5.7 8.0 7.3 8.9 8.5 6.3 7.8 10.2 9.7 8.8 5.3 11.3 12.6 6.3 6.4 9.6 10.6 6.8 9.1 7.3 8.1 5.5 33.0 7.7 9.2 4.8 26.1 13.2 11.7 9.0 10.2 7.5 13.7 6.7 32.8 6.3 31.6 12.8 14.6 13.5 8.0 17.9 14.6 13.2 11.1 6.6 8.8 38.2 6.0 8.8 9.9 17.5 14.2 8.3 14.6 22.7 18.3 9.7 3.8 11.3 11.4 4.2 9.4 6.0 4.4 10.5 10.0 6.3 7.6 7.2 12.1 12.0 7.5 8.8 5.5 9.0 5.2 10.2 4.4 6.0 21.1 10.9 7.9 8.5 4.5 16.3 12.3 6.5 17.4 6.4 6.6 6.6 6.8 12.3 7.2 10.4 8.2 7.7 7.2 6.8 7.4 6.4 8.0 9.1 7.0 9.3 11.6 7.1 7.1 6.0 5.0 5.4 7.3 6.3 7.1 5.1 5.4 5.8 5.7 5.3 6.4 5.5 9.6 35.3 28.9 17.3 30.9 40.9 13.4 98.8 13.6 14.9 26.1 10.7 19.5 62.9 36.9 44.1 12.5 20.0 26.7 13.5 19.6 89.7 4.1 11.8 10.2 18.1 20.9 12.6 27.7 62.1 37.7 18.6 15.8 18.5 21.0 10.9 42.8 48.7 29.7 25.2 25.1 13.1 34.6 23.6 46.3 4.3 12.8 19.0 32.0 20.6 23.4 22.8 16.5 27.2 20.5 92.5 14.4 14.3 50.8 25.3 34.4 29.6 23.9 12.4 0.0 21.3 30.1 38.1 16.1 11.6 40.1 19.8 21.5 8.4 13.2 32.1 INSL3 "MGC119818, MGC119819, RLF, RLNL" ENSG00000248099 "Insulin like 3" P51460 19 17816512-17821574 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted secreted proteins" Hormone "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "testis: 409.3" "Cell type enriched" "Detected in some" 19 "Theca cells: 24080.8" "Cancer enriched" "Detected in many" 21 "testis cancer: 39.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "Karpas-707: 5.7;PC-3: 2.6;SCLC-21H: 5.2;SH-SY5Y: 4.7" HPA028615 Enhanced "Secreted to blood" NA NA 566000 "Cluster 1: Neutrophils - Mixed function" "Cluster 83: Testis - Spermatogenesis" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 52: Non-specific - Transcription" "HPA028615: AB_10600717" "unprognostic (3.25e-1)" "unprognostic (2.25e-4)" "unprognostic (3.50e-5)" "unprognostic (7.04e-2)" "unprognostic (1.74e-4)" "unprognostic (4.60e-2)" "unprognostic (2.03e-1)" "unprognostic (1.58e-2)" "unprognostic (1.44e-1)" "unprognostic (1.73e-1)" "unprognostic (4.46e-1)" "unprognostic (4.93e-2)" "unprognostic (9.51e-10)" "unprognostic (6.80e-3)" "unprognostic (1.41e-1)" "unprognostic (8.85e-2)" "unprognostic (1.09e-5)" 0.5 1.6 1.2 4.8 1.3 1.8 0.5 2.3 1.5 0.1 1.3 0.5 1.5 0.3 0.8 0.6 0.8 0.4 0.2 1.4 1.5 0.5 0.4 0.9 2.9 1.2 1.3 29.6 0.2 0.0 0.2 0.3 1.4 0.6 0.0 0.1 0.6 0.0 0.2 0.3 1.7 0.0 1.2 5.2 0.8 409.3 1.5 0.5 0.3 0.4 1.2 0.4 0.3 1.3 0.2 0.6 0.1 0.5 0.1 0.0 1.2 0.0 0.0 0.0 0.0 0.1 1.1 0.1 1.4 0.0 0.2 0.0 0.0 0.0 0.0 1.2 0.1 0.5 0.0 0.2 0.0 0.0 1.2 0.8 0.6 0.0 0.0 0.0 0.0 0.1 0.0 5.7 0.0 1.0 0.2 1.1 0.0 1.1 2.6 0.9 0.0 0.1 0.1 0.3 5.2 4.7 0.0 1.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.4 0.0 0.4 2.1 0.1 0.1 1.3 0.0 0.4 0.2 0.0 0.7 0.4 0.7 0.0 0.9 0.9 0.1 1.1 0.7 1.0 2.2 0.5 0.1 0.1 0.8 0.5 1.2 1.3 2.3 1.5 1.4 1.5 1.2 1.3 1.4 1.2 1.5 1.3 0.4 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.7 2.3 0.0 0.0 0.1 6.8 0.0 0.1 3.4 0.0 0.0 0.3 0.0 0.4 42.3 0.0 0.0 0.0 0.9 0.4 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 257.1 1240.2 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 998.6 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.1 2.9 5.7 0.0 0.0 0.5 0.8 24080.8 0.0 0.0 INSM1 "IA-1, IA1" ENSG00000173404 "INSM transcriptional repressor 1" Q01101 20 20368104-20370949 "Predicted intracellular proteins, Transcription factors" "Cell cycle, Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 13.4;pituitary gland: 29.2" "Cell type enriched" "Detected in some" 42 "Enteroendocrine cells: 506.7" "Cancer enhanced" "Detected in many" "glioma: 9.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 19 "SCLC-21H: 370.4" "Low region specificity" "Detected in many" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "unprognostic (1.86e-2)" "unprognostic (5.25e-4)" "unprognostic (7.59e-2)" "unprognostic (3.49e-2)" "unprognostic (1.07e-1)" "unprognostic (1.07e-3)" "unprognostic (4.34e-2)" "unprognostic (2.89e-2)" "unprognostic (1.40e-1)" "unprognostic (2.38e-3)" "unprognostic (1.33e-1)" "unprognostic (1.52e-1)" "unprognostic (2.77e-1)" "unprognostic (1.33e-1)" "unprognostic (5.23e-1)" "unprognostic (1.22e-1)" 0.2 7.1 2.4 0.6 5.9 0.0 0.0 13.4 3.1 0.0 0.0 1.3 3.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 4.6 0.0 0.0 0.0 0.5 0.9 2.5 0.0 2.9 0.0 29.2 0.0 1.5 0.2 1.8 0.1 0.0 0.2 0.0 0.1 2.1 0.0 0.4 0.2 5.1 0.4 3.3 2.8 0.0 0.0 0.3 0.1 0.0 2.1 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 2.3 0.0 0.0 0.1 3.2 19.4 0.0 0.0 370.4 0.3 0.0 0.3 0.0 1.1 0.9 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.4 5.9 13.4 3.1 2.5 4.6 0.9 2.5 1.5 0.4 3.3 2.1 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.4 1.9 0.0 0.0 0.2 0.1 0.1 506.7 0.0 0.8 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 1.4 10.8 0.0 0.0 0.7 0.0 0.0 0.2 3.6 0.0 11.9 0.0 0.0 0.5 3.1 1.5 2.3 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.2 1.5 0.0 0.0 0.0 0.0 0.0 2.1 0.0 INTS7 "C1orf73, DKFZP434B168, INT7" ENSG00000143493 "Integrator complex subunit 7" Q9NVH2 1 211940399-212035557 "Predicted intracellular proteins" "DNA damage" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 35.6;Oligodendrocytes: 46.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072611 Supported "Nuclear bodies" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nuclear bodies" "HPA072611: AB_2732204" "unprognostic (1.25e-1)" "unprognostic (2.92e-1)" "unprognostic (1.81e-1)" "unprognostic (2.63e-2)" "unprognostic (4.26e-2)" "unprognostic (5.74e-2)" "unprognostic (1.65e-2)" "unprognostic (4.66e-3)" "unprognostic (2.80e-3)" "unprognostic (1.37e-2)" "unprognostic (9.80e-2)" "unprognostic (4.46e-1)" "prognostic unfavorable (1.42e-5)" "unprognostic (2.48e-1)" "unprognostic (4.17e-2)" "unprognostic (2.11e-1)" "unprognostic (7.44e-2)" 5.5 5.1 5.4 6.3 7.1 7.9 6.7 5.8 8.5 5.1 5.3 6.3 5.8 4.6 6.6 8.2 4.5 4.5 4.7 5.3 5.7 4.4 11.1 5.1 9.1 6.0 6.1 4.3 4.7 2.7 5.6 5.8 6.8 5.5 7.6 7.8 4.2 3.1 5.4 7.6 5.4 7.1 5.5 6.0 5.3 21.4 5.7 13.6 6.6 8.5 10.2 6.4 5.5 9.0 31.1 27.2 21.4 17.1 15.3 16.7 25.7 24.9 15.8 29.2 36.8 25.8 26.4 36.0 13.1 18.1 22.7 27.9 32.2 20.0 24.2 34.8 27.5 31.3 27.9 19.0 16.6 56.3 27.9 14.9 24.1 46.8 35.4 13.8 17.7 19.5 46.8 31.2 24.3 18.1 45.6 16.1 39.2 21.3 26.8 27.9 39.7 53.0 16.9 23.2 36.1 28.2 32.4 34.7 20.6 24.7 28.9 26.7 12.6 23.7 25.5 22.0 37.5 13.5 24.3 42.8 21.0 22.8 27.2 12.6 7.3 6.1 8.7 7.5 7.3 9.4 8.7 10.4 10.9 10.9 5.2 6.4 0.8 22.2 10.0 7.6 15.0 7.6 5.4 7.1 5.8 8.5 5.3 5.7 6.0 6.1 6.8 5.5 5.7 9.0 2.4 0.0 12.0 9.1 7.3 9.9 8.2 4.6 10.8 8.5 5.9 3.7 4.9 5.7 4.6 3.7 4.2 10.5 6.9 6.7 1.9 5.1 35.0 5.1 4.9 4.6 1.2 11.6 20.4 7.0 7.9 5.7 6.6 4.5 4.5 8.1 4.6 10.8 5.5 5.0 24.5 5.6 6.1 4.7 5.1 35.6 5.0 3.8 1.8 19.7 6.2 4.2 10.3 34.7 46.6 5.5 1.9 6.8 9.1 4.2 4.4 3.3 6.2 5.6 0.0 5.4 4.5 31.5 18.8 9.9 11.9 6.8 6.7 17.7 8.3 3.9 INTS8 "C8orf52, FLJ20530, INT8, MGC131633" ENSG00000164941 "Integrator complex subunit 8" Q75QN2 8 94813311-94881746 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057299 Approved Approved Nucleoplasm Yes No "Cluster 26: Non-specific - Mitochondria" "Cluster 23: Testis - Cell cycle regulation" "Cluster 21: OE19 - Mitochondria" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA057299: AB_2683403" "unprognostic (1.08e-2)" "unprognostic (3.12e-2)" "unprognostic (1.28e-1)" "unprognostic (5.86e-2)" "unprognostic (1.96e-1)" "unprognostic (4.81e-2)" "prognostic unfavorable (2.54e-6)" "unprognostic (3.07e-2)" "unprognostic (6.87e-2)" "unprognostic (9.77e-3)" "unprognostic (4.84e-2)" "unprognostic (1.53e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.24e-1)" "unprognostic (5.60e-2)" "unprognostic (1.11e-1)" "unprognostic (3.96e-2)" 8.8 7.5 4.4 13.9 4.8 15.5 8.1 8.3 6.4 14.5 6.9 12.8 7.8 13.2 4.2 10.5 9.5 7.3 10.2 4.8 6.4 6.4 8.9 7.5 17.4 5.7 4.4 11.4 13.5 10.1 8.3 9.4 4.6 10.4 14.8 10.3 11.0 8.7 12.6 10.3 10.6 13.6 4.0 9.9 10.6 30.6 6.3 20.6 8.8 12.0 13.6 10.4 10.4 6.1 52.4 31.9 49.2 43.4 17.7 41.7 25.5 27.5 26.0 35.7 33.0 22.5 38.0 52.3 25.2 20.7 44.3 31.5 61.3 29.2 47.6 58.1 28.8 45.7 19.3 22.1 21.1 24.6 31.7 17.1 13.5 34.7 29.6 40.8 40.1 35.1 44.4 38.9 22.0 34.5 53.7 20.4 28.1 114.9 55.8 42.7 19.7 29.0 30.0 26.6 34.6 18.4 26.8 7.7 24.1 40.3 37.3 31.6 28.1 16.1 18.9 31.1 25.1 22.0 43.0 45.2 21.6 49.4 32.2 2.1 9.6 15.1 4.6 6.8 7.5 13.4 10.8 11.8 9.3 10.4 11.0 6.5 9.3 9.6 6.6 5.5 10.0 4.5 4.4 4.8 8.3 6.4 4.8 6.4 5.7 4.4 4.6 4.0 6.3 6.1 11.0 16.0 8.6 16.6 19.4 5.9 11.6 9.1 9.6 13.7 6.1 4.6 8.3 5.7 11.6 7.3 33.3 10.0 9.7 10.3 3.9 8.3 36.0 15.0 12.1 11.8 18.0 17.7 44.8 13.4 12.9 10.8 8.6 6.1 12.7 15.2 8.9 5.5 9.5 28.6 40.9 11.8 8.2 11.6 6.6 6.4 16.1 14.0 7.2 25.3 21.6 8.0 16.5 33.2 31.2 10.9 14.6 16.1 18.0 8.8 9.5 5.1 19.7 18.9 6.6 10.6 13.1 54.7 32.5 9.0 7.0 8.5 14.2 11.0 11.1 8.1 IQCF5 ENSG00000214681 "IQ motif containing F5" A8MTL0 3 51873721-51875601 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 487 "testis: 104.4" "Group enriched" "Detected in some" 92 "Early spermatids: 926.1;Late spermatids: 2733.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (3.45e-1)" 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 104.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 926.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2733.9 12.5 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 19.7 0.0 0.0 18.6 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IQCH FLJ12476 ENSG00000103599 "IQ motif containing H" Q86VS3 15 67254786-67502260 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 11.5" "Cell type enhanced" "Detected in many" "Astrocytes: 27.4;Early spermatids: 59.4;Excitatory neurons: 26.5;Late spermatids: 37.3;Respiratory ciliated cells: 30.3;Spermatocytes: 48.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA040845 Uncertain Approved Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "HPA040845: AB_10672898" "unprognostic (2.69e-1)" "unprognostic (2.94e-3)" "unprognostic (3.11e-2)" "unprognostic (5.89e-5)" "unprognostic (2.48e-1)" "unprognostic (9.83e-2)" "unprognostic (2.57e-1)" "unprognostic (1.18e-1)" "unprognostic (2.64e-1)" "unprognostic (3.25e-1)" "unprognostic (5.37e-2)" "unprognostic (1.70e-1)" "unprognostic (1.51e-3)" "unprognostic (2.81e-1)" "unprognostic (3.81e-2)" "unprognostic (6.16e-3)" "unprognostic (6.42e-2)" 0.3 1.1 0.7 0.3 0.8 0.1 1.6 0.7 1.4 0.9 4.2 0.5 0.2 0.8 2.6 0.5 6.8 0.6 0.9 0.7 1.8 2.2 1.0 0.9 0.4 2.5 2.2 0.3 0.7 3.7 2.0 0.4 1.6 0.6 0.7 5.0 0.6 0.8 0.5 0.6 0.1 0.3 2.0 0.4 1.1 11.5 1.9 1.0 4.1 0.0 0.2 0.7 0.3 1.4 1.7 1.6 0.8 1.3 1.1 2.6 0.6 0.9 0.7 1.3 0.9 0.1 1.9 1.2 0.8 1.5 1.5 2.8 2.6 1.0 2.3 0.2 1.2 0.3 1.6 0.2 1.7 0.5 0.3 1.7 1.1 2.9 2.8 1.3 0.5 3.1 2.6 1.1 1.0 1.8 0.4 0.4 0.9 1.0 1.1 0.3 1.2 1.3 1.6 0.7 2.6 0.7 1.2 1.6 4.8 1.6 4.3 0.3 1.2 1.5 0.7 2.4 1.0 2.5 3.2 0.3 3.1 1.3 1.4 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.7 0.8 0.7 1.4 0.7 1.8 2.5 2.2 1.6 2.0 1.9 1.4 0.7 3.2 1.1 27.4 0.3 1.3 1.0 1.6 1.8 1.5 2.7 2.2 1.1 0.0 2.8 1.8 8.4 0.2 0.3 0.4 0.0 1.0 59.4 15.9 1.1 0.9 0.0 0.4 26.5 0.8 0.5 0.7 8.2 2.0 0.0 0.7 0.0 0.0 0.3 1.7 18.2 0.5 4.1 0.0 0.7 37.3 0.9 0.3 0.0 8.4 1.0 1.1 0.0 9.0 9.5 0.7 0.0 0.7 0.5 0.3 0.2 2.2 30.3 5.4 0.0 1.5 0.6 48.8 18.2 1.2 0.4 0.3 0.4 4.2 0.4 1.0 IQUB FLJ35834 ENSG00000164675 "IQ motif and ubiquitin domain containing" Q8NA54 7 123452193-123535077 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "testis: 33.4" "Group enriched" "Detected in many" 7 "Early spermatids: 283.9;Endometrial ciliated cells: 82.6;Late spermatids: 157.5;Respiratory ciliated cells: 88.2;Spermatocytes: 116.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "RPTEC TERT1: 2.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA049626 Approved "Nucleoplasm,Nuclear speckles,Intermediate filaments,Cytosol" NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 49: Ciliated cells - Cilium organization" "Nuclear speckles" "Nucleoplasm, Intermediate filaments, Cytosol" "HPA049626: AB_2732554" "unprognostic (8.71e-2)" "unprognostic (1.25e-2)" "unprognostic (1.98e-1)" "unprognostic (6.42e-4)" "unprognostic (1.91e-1)" "unprognostic (1.44e-2)" "unprognostic (6.23e-2)" "unprognostic (7.97e-2)" "unprognostic (1.46e-1)" "unprognostic (1.73e-1)" "unprognostic (2.40e-2)" "unprognostic (3.76e-1)" "unprognostic (5.44e-6)" "unprognostic (2.79e-1)" "unprognostic (9.78e-3)" "unprognostic (2.14e-1)" "unprognostic (7.30e-2)" 0.1 0.6 0.2 0.0 0.4 0.0 0.5 1.7 0.9 0.8 3.9 0.1 0.0 0.7 1.1 0.0 5.0 0.8 0.1 0.2 0.5 3.0 0.0 0.8 0.0 1.8 2.0 0.2 0.3 1.7 1.0 0.1 1.3 0.5 0.0 1.1 0.2 0.6 0.1 0.1 0.0 0.2 1.0 0.0 0.1 33.4 0.6 0.0 3.0 0.1 0.0 0.1 0.1 0.4 0.1 0.0 0.4 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.5 0.3 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 1.7 0.9 0.2 0.5 1.8 2.0 1.3 1.0 0.6 0.4 1.1 6.4 0.5 19.6 0.0 0.5 0.7 3.8 0.0 2.5 1.9 1.8 1.8 0.0 11.4 18.4 4.2 0.4 0.1 0.1 1.9 1.1 283.9 82.6 3.2 0.9 1.8 0.0 12.0 0.4 0.3 1.1 0.0 1.7 1.3 0.3 0.7 0.0 0.1 3.3 8.6 0.2 8.2 0.0 0.3 157.5 2.5 0.4 0.0 4.7 0.3 1.8 0.0 5.0 2.6 0.2 0.0 3.0 0.0 0.5 0.0 5.7 88.2 9.0 6.6 0.7 2.7 116.2 6.0 0.2 0.1 0.7 0.3 2.9 0.0 0.3 IRF5 ENSG00000128604 "Interferon regulatory factor 5" Q13568 7 128937457-128950038 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Antiviral defense, Immunity, Inflammatory response, Innate immunity, Transcription, Transcription regulation" DNA-binding "Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Collecting duct cells: 20.2;Hofbauer cells: 38.4;Kupffer cells: 34.5;Macrophages: 27.8;monocytes: 76.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 6 "B-cells: 17.6;dendritic cells: 43.6;monocytes: 53.1" "Cell line enhanced" "Detected in many" "HDLM-2: 124.3;RPMI-8226: 91.9;THP-1: 50.0;U-937: 62.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA046700, HPA076024" Enhanced NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "HPA046700: AB_2679761, HPA076024: " "unprognostic (4.01e-2)" "unprognostic (2.73e-2)" "unprognostic (1.05e-1)" "unprognostic (1.92e-2)" "unprognostic (3.45e-1)" "unprognostic (1.57e-2)" "unprognostic (5.69e-3)" "unprognostic (1.49e-1)" "unprognostic (2.74e-1)" "unprognostic (4.84e-2)" "unprognostic (1.51e-1)" "unprognostic (6.85e-2)" "unprognostic (1.53e-3)" "unprognostic (2.66e-1)" "unprognostic (4.89e-2)" "unprognostic (6.58e-2)" "unprognostic (3.20e-3)" 5.5 3.5 4.8 13.1 3.9 20.6 3.2 4.9 5.2 3.2 3.9 4.4 9.5 1.6 3.0 12.6 4.5 6.3 1.8 4.3 6.4 13.5 5.1 10.6 16.2 8.7 6.3 1.0 5.9 6.4 5.2 3.9 7.4 3.3 3.6 0.5 6.8 12.7 0.8 8.6 11.2 3.1 7.6 24.0 4.6 1.2 7.9 4.2 2.2 1.2 11.8 6.5 5.8 11.3 13.9 4.6 0.0 1.4 0.0 0.0 0.0 0.2 0.1 1.2 0.9 0.3 5.7 10.8 5.2 0.2 12.1 12.9 3.4 2.6 0.3 124.3 2.9 18.3 0.3 1.9 0.0 2.7 25.4 0.0 15.1 0.3 1.8 1.0 0.0 0.1 0.0 31.5 0.0 5.0 0.0 4.8 0.3 1.7 2.6 0.8 0.1 91.9 3.8 8.1 0.4 2.0 2.7 3.0 1.4 0.0 4.8 50.0 0.0 0.0 0.3 0.5 1.2 19.4 13.5 4.5 0.5 62.6 0.3 1.8 42.7 4.2 1.0 53.1 4.0 17.6 2.3 0.8 43.6 15.0 0.1 0.1 2.9 4.9 38.0 10.4 6.2 22.7 4.8 3.9 4.9 5.2 4.3 6.4 8.7 6.3 7.4 7.6 7.9 11.3 0.1 0.0 3.6 0.0 12.7 0.8 0.8 2.2 0.0 0.3 0.8 0.9 0.8 2.8 2.4 20.2 0.0 0.3 7.2 0.8 3.9 3.1 0.2 2.8 0.3 0.9 0.0 6.1 0.4 2.4 0.3 0.3 2.0 2.6 8.8 0.5 0.0 1.2 38.4 0.0 0.3 1.5 0.0 34.5 16.5 0.2 0.0 27.8 0.0 8.4 76.1 0.0 3.1 0.0 0.1 2.3 1.7 0.0 9.3 0.7 4.9 6.2 10.1 0.3 0.0 0.2 0.7 0.1 0.5 2.8 2.0 1.5 3.0 0.0 1.5 2.1 IRF8 "ICSBP, ICSBP1, IRF-8" ENSG00000140968 "Interferon regulatory factor 8" Q02556 16 85899162-85922606 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Autophagy, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 85.5;lymphoid tissue: 244.1" "Cell type enhanced" "Detected in many" "B-cells: 225.8;dendritic cells: 492.3;Kupffer cells: 105.1;Langerhans cells: 366.0;Macrophages: 122.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "plasmacytoid DC: 2477.4" "Lineage enriched" "Detected in all" 7 "dendritic cells: 2477.4" "Group enriched" "Detected in some" 4 "Daudi: 240.7;THP-1: 382.3;U-698: 928.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002267, HPA002531, CAB013480" Enhanced Enhanced Nucleoplasm NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "CAB013480: AB_2533439, HPA002267: AB_1079143, HPA002531: AB_1851904" "unprognostic (2.09e-3)" "unprognostic (7.51e-2)" "unprognostic (5.16e-2)" "unprognostic (1.19e-1)" "unprognostic (7.54e-2)" "unprognostic (3.46e-3)" "unprognostic (3.19e-2)" "unprognostic (5.31e-3)" "unprognostic (1.23e-1)" "unprognostic (1.20e-1)" "unprognostic (1.66e-1)" "unprognostic (5.31e-2)" "unprognostic (3.14e-3)" "unprognostic (3.97e-2)" "unprognostic (9.66e-3)" "unprognostic (4.04e-1)" "unprognostic (1.10e-2)" 25.9 7.6 4.7 81.4 5.6 85.5 9.3 7.0 6.2 5.6 5.4 27.1 47.1 8.0 3.1 6.7 6.5 19.7 3.8 6.3 5.4 6.1 36.9 27.4 244.1 9.5 8.5 2.5 3.4 1.7 1.7 10.1 10.0 7.7 33.5 0.8 7.1 8.9 2.0 5.0 56.2 13.5 11.3 137.3 22.9 4.8 12.6 61.5 4.1 1.7 224.9 21.8 1.6 14.0 0.9 0.0 0.0 0.0 0.0 0.0 16.9 0.0 0.0 0.0 0.0 26.0 0.0 240.7 1.5 0.0 0.0 0.1 1.4 0.0 0.2 0.2 2.7 0.1 0.0 0.0 1.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.3 0.5 0.0 0.0 0.6 21.3 0.2 20.6 0.0 7.5 1.1 27.2 0.0 0.0 0.1 0.1 1.0 0.0 0.2 1.4 0.0 382.3 0.6 0.0 10.9 0.2 0.9 0.3 0.3 928.2 0.0 128.4 0.0 9.1 137.1 3.4 3.3 134.3 4.5 347.0 1.8 2.1 291.2 361.3 3.5 2.8 8.4 111.5 97.3 2477.4 0.7 150.1 4.7 5.6 7.0 6.2 6.3 5.4 9.5 8.5 10.0 11.3 12.6 14.0 3.7 0.0 4.2 0.0 225.8 10.5 0.8 0.0 0.6 0.0 2.4 3.4 1.5 2.8 1.3 0.0 0.0 0.8 492.3 13.0 1.9 0.5 1.5 7.3 7.6 7.6 28.7 7.4 0.6 1.4 5.7 10.8 15.3 12.5 2.5 0.4 1.8 6.5 64.1 0.0 0.2 11.8 0.0 105.1 366.0 4.6 0.3 122.2 44.4 33.7 35.3 0.4 23.7 1.0 0.4 0.1 10.7 0.0 14.1 2.3 34.2 3.5 0.0 0.2 6.6 0.7 6.7 0.7 6.7 0.4 9.2 1.1 23.1 48.8 25.6 2.5 ISG20L2 FLJ12671 ENSG00000143319 "Interferon stimulated exonuclease gene 20 like 2" Q9H9L3 1 156721891-156728766 "Predicted intracellular proteins" "Ribosome biogenesis" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "testis: 95.7" "Group enriched" "Detected in all" 30 "Early spermatids: 816.3;Late spermatids: 2897.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028005, HPA054285" Approved Approved Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 83: Testis - Spermatogenesis" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "HPA028005: AB_2126319, HPA054285: " "unprognostic (1.67e-2)" "unprognostic (7.87e-2)" "unprognostic (2.80e-1)" "prognostic unfavorable (4.63e-4)" "unprognostic (3.52e-1)" "unprognostic (1.65e-2)" "prognostic unfavorable (6.15e-5)" "unprognostic (1.02e-1)" "unprognostic (9.55e-2)" "unprognostic (6.05e-2)" "unprognostic (2.40e-1)" "unprognostic (8.17e-2)" "prognostic unfavorable (4.80e-5)" "unprognostic (5.11e-2)" "unprognostic (2.68e-1)" "unprognostic (3.82e-3)" "unprognostic (2.32e-1)" 12.0 10.5 6.2 11.4 6.1 16.7 10.7 8.3 8.1 10.7 4.9 12.5 9.2 12.9 7.5 18.5 11.5 9.0 10.2 6.9 6.2 11.8 13.5 10.0 14.9 6.1 6.0 13.8 11.7 9.3 9.1 11.9 5.8 11.3 12.3 6.6 11.3 8.0 9.8 14.6 12.0 12.4 5.6 13.3 12.2 95.7 6.0 12.2 9.7 6.6 17.0 15.3 12.4 6.3 29.8 22.6 19.1 20.5 19.4 14.2 29.5 20.4 17.9 26.3 18.2 30.2 21.3 56.7 24.3 15.3 11.9 39.2 47.0 32.2 19.9 28.4 30.6 30.9 16.4 17.8 18.9 73.7 32.3 14.3 32.4 24.6 24.7 17.1 24.2 23.9 49.5 25.4 17.0 40.4 31.8 21.3 62.9 60.3 38.0 37.5 22.3 35.9 19.6 23.8 40.4 48.5 24.8 69.8 21.3 27.8 44.5 45.8 16.2 15.2 22.4 18.8 41.9 33.9 56.3 70.3 13.8 37.1 20.2 28.2 8.7 17.2 8.5 11.0 9.8 7.2 6.5 8.7 8.2 8.6 6.6 7.7 15.1 12.1 12.4 5.5 6.7 6.1 6.2 6.1 8.3 8.1 6.9 6.2 6.1 6.0 5.8 5.6 6.0 6.3 16.4 28.9 43.4 4.9 43.6 52.9 40.4 18.9 46.7 22.4 30.5 23.6 10.1 18.6 29.1 7.3 25.0 34.9 57.7 32.0 17.6 21.2 816.3 21.7 22.8 24.9 31.8 29.8 13.5 17.3 37.5 24.2 26.0 38.5 27.8 22.7 21.4 18.6 21.3 23.5 9.8 32.3 10.2 28.4 38.0 2897.0 29.2 33.2 23.2 2.8 21.6 19.8 36.0 6.0 6.3 23.6 16.7 25.9 38.4 38.0 33.8 13.9 19.5 20.5 26.3 30.2 24.5 48.0 27.3 41.7 60.7 37.5 51.5 23.4 31.5 45.8 ITGA1 "CD49a, VLA1" ENSG00000213949 "Integrin subunit alpha 1" P56199 5 52787916-52959209 "Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins, Transporters" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 36.6" "Cell type enhanced" "Detected in many" "Adipocytes: 264.1;Endothelial cells: 120.5;Hepatocytes: 110.5;Sertoli cells: 98.6;Smooth muscle cells: 143.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 4.5;HHSteC: 4.5;SH-SY5Y: 1.7;WM-115: 2.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042555 Uncertain NA NA 6300000 "Cluster 72: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA042555: AB_10794281" "unprognostic (1.48e-1)" "unprognostic (1.07e-2)" "unprognostic (2.44e-1)" "unprognostic (1.33e-1)" "unprognostic (1.38e-1)" "unprognostic (9.89e-3)" "unprognostic (2.74e-1)" "unprognostic (1.72e-1)" "unprognostic (1.79e-3)" "unprognostic (1.50e-2)" "unprognostic (2.62e-1)" "unprognostic (9.86e-2)" "prognostic unfavorable (2.24e-4)" "unprognostic (3.13e-3)" "unprognostic (2.06e-2)" "unprognostic (1.07e-2)" "unprognostic (1.62e-2)" 13.9 22.4 0.6 1.0 0.8 0.0 10.2 0.7 0.9 5.1 0.4 36.6 1.1 16.3 2.5 5.7 9.9 2.2 10.6 0.5 0.8 11.0 17.1 22.1 0.8 0.8 0.8 3.6 3.1 2.1 2.3 5.8 0.8 12.6 2.7 0.1 2.3 7.2 4.6 2.3 12.5 5.8 0.8 27.9 16.6 0.8 0.8 0.2 9.7 2.5 0.4 17.9 5.1 0.9 0.0 0.0 0.3 0.0 1.4 0.4 0.1 0.3 1.3 0.3 0.7 0.7 0.0 0.0 0.1 4.5 0.5 0.2 0.1 0.4 0.2 0.0 0.4 0.0 0.3 0.3 4.5 0.0 0.0 0.7 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 1.7 0.5 0.0 0.0 0.7 0.0 0.0 0.6 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.8 0.7 0.9 0.5 0.8 0.8 0.8 0.8 0.8 0.8 0.9 264.1 54.5 26.8 2.9 1.7 3.2 4.7 1.5 2.8 1.8 3.6 13.8 12.6 5.7 8.7 5.5 2.1 1.5 2.9 5.5 1.9 3.0 21.3 7.7 41.8 120.5 16.4 5.3 3.6 5.4 16.8 40.2 6.1 22.1 10.1 1.0 77.1 110.5 2.2 0.0 19.5 14.0 0.0 7.2 8.2 6.1 9.3 5.6 7.2 63.7 9.1 0.4 0.0 1.5 4.2 19.6 7.7 8.2 2.9 3.2 6.5 15.1 6.3 2.0 98.6 18.6 143.9 0.9 1.1 0.5 3.1 3.4 46.0 13.6 14.0 2.3 ITGA2B "CD41, CD41B, GP2B, PPP1R93" ENSG00000005961 "Integrin subunit alpha 2b" P08514 17 44372180-44389649 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 16.6;epididymis: 10.7;lymphoid tissue: 11.2" "Cell type enhanced" "Detected in many" "Early spermatids: 16.1;Erythroid cells: 43.5;granulocytes: 17.8;Late spermatids: 24.8;Macrophages: 23.0" "Cancer enhanced" "Detected in some" "testis cancer: 2.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 14 "basophil: 64.5" "Lineage enriched" "Detected in single" 75 "granulocytes: 64.5" "Group enriched" "Detected in some" 14 "HEL: 404.6;HMC-1: 631.7" "Not detected" "Not detected" "CAB018611, HPA031168, HPA031169, HPA031170, HPA031171" Enhanced Approved "Plasma membrane" NA NA 90000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane" "CAB018611: AB_2265153, HPA031168: AB_10664706, HPA031169: AB_10669671, HPA031170: AB_10696214, HPA031171: AB_10669773" "unprognostic (6.11e-2)" "unprognostic (3.23e-2)" "unprognostic (1.23e-1)" "unprognostic (4.85e-2)" "unprognostic (1.59e-2)" "unprognostic (3.98e-3)" "unprognostic (4.23e-5)" "unprognostic (1.25e-1)" "unprognostic (1.33e-2)" "unprognostic (7.22e-2)" "unprognostic (2.97e-3)" "unprognostic (1.30e-1)" "unprognostic (8.83e-9)" "unprognostic (7.82e-2)" "unprognostic (1.85e-1)" "unprognostic (1.95e-1)" "unprognostic (2.25e-1)" 0.8 0.2 3.7 0.2 3.6 16.6 0.4 4.0 4.8 1.5 3.8 0.3 0.0 0.9 10.7 0.3 1.5 0.8 1.4 3.5 3.6 1.0 0.5 5.1 0.2 3.6 3.5 1.5 0.1 1.3 1.9 1.1 3.6 0.6 0.1 1.6 0.1 0.8 0.6 0.1 0.3 0.2 3.3 11.2 0.3 2.9 3.5 0.1 3.1 1.1 0.1 0.2 0.7 3.7 0.5 0.7 2.2 0.3 0.1 0.3 18.4 0.3 0.1 0.8 0.6 0.0 0.2 0.0 0.3 0.0 0.2 0.6 1.8 0.0 0.4 0.4 1.1 404.6 0.3 1.3 0.0 0.2 631.7 0.4 0.0 0.2 0.0 0.0 0.0 0.3 0.7 1.1 0.0 0.7 0.5 36.4 0.8 0.0 0.7 0.7 0.2 0.0 0.0 0.1 0.4 1.0 0.5 0.5 0.1 1.5 4.5 0.9 0.3 0.2 0.7 0.0 0.0 0.4 0.2 0.3 0.4 0.3 0.8 64.5 0.3 4.0 0.1 0.0 0.3 0.0 0.0 0.0 0.5 0.1 0.0 0.0 4.5 0.0 0.0 0.8 0.0 19.3 3.7 3.6 4.0 4.8 3.5 3.6 3.6 3.5 3.6 3.3 3.5 3.7 0.3 0.0 1.5 1.0 0.4 0.3 0.4 0.1 1.8 5.1 0.2 1.1 1.5 1.5 1.3 5.5 8.4 1.3 0.1 0.6 0.0 0.0 16.1 1.0 0.7 2.1 0.0 43.5 4.1 0.0 1.4 1.1 0.0 3.2 17.8 0.1 3.6 0.0 0.2 3.3 2.8 0.0 0.0 3.1 0.7 24.8 1.8 23.0 0.0 1.0 2.9 1.3 0.0 9.5 4.6 0.1 0.0 1.9 0.1 0.3 0.0 0.0 0.0 3.0 0.0 1.8 0.7 3.4 7.4 0.5 0.0 0.7 0.6 0.1 0.3 0.3 ITGB2 "CD18, LFA-1, MAC-1, MFI7" ENSG00000160255 "Integrin subunit beta 2" P05107 21 44885953-44931989 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Phagocytosis" "Integrin, Receptor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 376.2;lymphoid tissue: 175.2" "Group enriched" "Detected in many" 6 "dendritic cells: 417.6;Hofbauer cells: 652.4;Kupffer cells: 485.9;Langerhans cells: 259.1;Macrophages: 527.4;monocytes: 463.8;NK-cells: 959.9;T-cells: 254.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 6 "THP-1: 812.4;U-937: 615.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008877, HPA016894" Enhanced Supported "Plasma membrane,Rods & Rings" NA NA 3300000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Rods & Rings" "HPA008877: AB_1846256, HPA016894: AB_1846257" "unprognostic (1.94e-2)" "unprognostic (7.66e-3)" "unprognostic (1.23e-1)" "unprognostic (6.21e-3)" "unprognostic (2.95e-2)" "unprognostic (9.73e-3)" "unprognostic (2.53e-2)" "unprognostic (1.82e-1)" "unprognostic (1.18e-2)" "unprognostic (1.36e-1)" "unprognostic (1.20e-1)" "unprognostic (6.34e-2)" "unprognostic (1.87e-3)" "unprognostic (1.42e-1)" "unprognostic (4.42e-2)" "unprognostic (2.65e-2)" "unprognostic (4.83e-2)" 54.5 23.2 8.2 175.2 9.5 376.2 15.4 13.1 9.3 15.5 11.7 25.2 23.8 8.5 2.8 16.2 17.0 36.4 11.8 7.7 14.2 8.4 23.4 78.0 169.1 29.5 19.9 7.2 11.3 5.1 4.6 44.4 28.1 8.8 13.9 1.1 19.5 9.2 6.8 9.3 32.8 46.4 23.9 137.2 29.1 5.9 26.2 87.2 7.3 7.6 68.4 46.3 5.9 50.4 1.9 4.8 0.0 0.0 0.0 0.3 1.7 0.0 2.7 0.1 0.0 0.4 0.4 17.9 128.1 0.2 0.6 0.5 0.0 0.2 0.0 1.5 1.4 18.2 0.0 3.2 0.1 106.6 27.5 1.6 0.1 0.5 0.3 0.1 0.3 58.0 0.7 1.4 7.0 4.0 117.8 126.1 0.4 0.4 2.4 1.5 23.2 64.6 4.7 0.0 0.6 1.3 3.4 2.5 1.7 0.0 0.4 812.4 2.5 0.2 6.6 0.4 3.7 0.8 5.9 2.9 0.1 615.0 0.9 186.6 1848.8 1224.1 726.7 1144.9 326.6 86.1 349.7 506.5 1031.4 115.2 233.1 396.5 1386.1 585.5 1183.5 165.5 288.0 3034.2 8.2 9.5 13.1 9.3 7.7 14.2 29.5 19.9 28.1 23.9 26.2 50.4 7.1 16.0 29.6 0.3 81.7 5.5 0.5 9.6 0.6 0.0 4.1 6.5 4.0 14.3 18.6 5.5 0.0 4.0 417.6 0.3 0.0 3.4 1.0 0.6 0.5 16.8 0.0 19.6 0.5 0.4 4.8 5.3 2.6 0.7 24.1 8.2 9.7 8.6 652.4 0.0 0.3 0.2 2.0 485.9 259.1 2.8 0.6 527.4 5.4 27.2 463.8 0.4 959.9 0.0 0.2 0.6 0.1 1.5 50.5 0.6 1.8 4.2 3.6 0.8 6.6 2.1 3.2 0.2 1.0 0.9 5.1 5.6 254.5 0.0 0.3 0.7 ITIH3 H3P ENSG00000162267 "Inter-alpha-trypsin inhibitor heavy chain 3" Q06033 3 52794768-52809009 "Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 97 "liver: 792.7" "Cell type enriched" "Detected in some" 8 "Hepatocytes: 1183.8" "Cancer enriched" "Detected in some" 247 "liver cancer: 273.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 24 "Hep G2: 17.3" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA017373 Approved "Secreted to blood" NA NA 9100000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "HPA017373: AB_1851954" "unprognostic (2.07e-2)" "unprognostic (5.79e-2)" "unprognostic (1.89e-1)" "unprognostic (3.30e-4)" "unprognostic (4.28e-2)" "unprognostic (3.26e-2)" "unprognostic (5.97e-2)" "unprognostic (6.07e-2)" "unprognostic (1.49e-1)" "unprognostic (7.05e-2)" "unprognostic (1.04e-1)" "unprognostic (3.19e-1)" "prognostic unfavorable (4.49e-8)" "unprognostic (2.09e-4)" "unprognostic (1.70e-1)" "unprognostic (2.55e-2)" "unprognostic (9.31e-2)" 5.0 0.7 0.5 0.9 0.7 0.0 2.1 0.5 0.8 5.3 0.4 1.1 0.3 3.5 1.7 1.3 3.4 1.2 0.7 0.5 0.4 0.7 792.7 3.0 2.5 0.4 0.4 2.8 0.3 0.1 0.3 1.7 0.5 1.1 1.0 0.1 0.4 2.4 0.6 1.3 1.2 1.2 0.4 8.1 1.2 3.5 0.4 0.2 1.2 0.4 1.7 1.4 2.3 0.5 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.3 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.7 0.5 0.8 0.5 0.4 0.4 0.4 0.5 0.4 0.4 0.5 0.1 0.0 0.0 0.0 21.6 0.1 0.0 0.0 0.0 0.5 0.1 1.4 0.8 78.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.2 0.1 0.1 3.5 0.0 90.9 0.0 0.0 0.1 2.1 0.0 0.0 0.0 12.3 66.4 1183.8 0.0 0.0 0.0 0.0 0.0 85.1 0.3 132.0 1.2 0.1 1.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 9.1 0.4 0.3 0.0 0.1 0.3 3.6 19.2 0.0 0.1 ITPR3 IP3R3 ENSG00000096433 "Inositol 1,4,5-trisphosphate receptor type 3" Q14573 6 33620365-33696574 "Human disease related genes, Plasma proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Ligand-gated ion channel, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 123.0;Gastric mucus-secreting cells: 127.4;Late spermatids: 220.4;Pancreatic endocrine cells: 89.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-HME1: 164.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA003915, HPA064704" Approved Uncertain Vesicles No Yes "Cluster 44: Non-specific - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 20: HeLa - Mitochondria" "Cluster 34: Spermatids - Unknown function" Vesicles "HPA003915: AB_1851845, HPA064704: " "unprognostic (2.57e-1)" "unprognostic (2.81e-2)" "unprognostic (1.52e-2)" "unprognostic (2.30e-1)" "unprognostic (5.40e-2)" "unprognostic (1.24e-1)" "unprognostic (2.08e-2)" "unprognostic (6.14e-2)" "unprognostic (3.35e-1)" "unprognostic (3.08e-2)" "unprognostic (4.14e-3)" "unprognostic (1.88e-1)" "unprognostic (6.44e-3)" "unprognostic (5.01e-2)" "unprognostic (1.74e-1)" "unprognostic (8.89e-2)" "unprognostic (2.43e-2)" 16.3 11.4 5.5 17.0 5.0 6.1 14.6 3.8 5.3 18.0 3.7 26.2 29.1 8.5 13.1 18.1 14.0 15.3 15.0 3.8 3.9 16.4 2.2 30.6 20.4 5.6 5.0 13.5 11.3 2.8 7.4 4.3 5.2 13.9 18.4 0.8 18.5 11.2 4.5 58.9 35.1 4.7 4.7 39.8 41.5 15.4 7.0 14.3 54.0 5.1 21.0 12.1 24.0 3.9 73.7 34.0 6.3 0.3 6.2 19.3 40.9 24.8 62.8 30.5 27.4 46.7 55.9 62.6 26.1 17.9 76.1 70.9 28.6 66.7 15.7 36.8 24.0 0.1 102.6 52.0 14.1 11.3 7.9 14.0 59.2 76.7 164.7 66.5 52.1 24.5 25.0 19.7 33.3 35.0 19.0 6.4 6.2 55.8 49.4 29.0 0.1 37.1 107.6 50.9 57.3 2.1 42.8 61.6 60.2 6.9 21.2 5.9 71.8 41.1 20.1 53.1 55.2 13.5 14.3 29.4 32.8 16.6 24.1 0.8 0.0 0.0 0.8 0.0 0.6 0.4 0.4 0.5 0.0 0.6 0.4 0.5 0.0 0.0 0.0 0.0 0.7 0.2 5.5 5.0 3.8 5.3 3.8 3.9 5.6 5.0 5.2 4.7 7.0 3.9 12.4 48.1 58.9 0.3 13.5 26.5 10.9 27.9 18.2 1.5 9.3 9.9 2.7 12.8 20.2 31.3 0.0 0.3 10.9 52.9 0.0 28.4 123.0 19.1 9.1 18.2 23.9 6.6 1.1 30.2 6.3 9.2 127.4 43.1 0.0 0.2 12.5 0.4 0.5 0.0 1.6 41.6 10.2 0.6 6.9 220.4 23.3 2.6 12.4 23.4 3.2 0.4 4.1 0.5 0.4 89.7 41.6 13.9 18.7 20.5 45.9 0.2 12.1 1.2 6.6 3.9 3.3 1.6 3.2 14.5 25.4 0.5 13.1 5.8 35.6 20.7 IZUMO2 "C19orf41, MGC33947, SCRL" ENSG00000161652 "IZUMO family member 2" Q6UXV1 19 50152548-50163195 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 283 "testis: 64.6" "Group enriched" "Detected in some" 41 "Early spermatids: 730.7;Late spermatids: 355.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA042143 Uncertain NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 34: Spermatids - Unknown function" "HPA042143: AB_10794078" "unprognostic (1.21e-2)" "unprognostic (3.18e-2)" "unprognostic (4.31e-2)" "unprognostic (1.81e-1)" "unprognostic (1.94e-1)" "unprognostic (1.78e-1)" "unprognostic (1.82e-1)" "unprognostic (1.07e-1)" "unprognostic (1.63e-1)" "unprognostic (8.75e-2)" 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 64.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.3 0.2 0.3 0.8 0.1 0.0 0.1 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 730.7 0.1 0.1 0.4 3.6 0.0 1.0 0.0 0.0 0.2 0.0 0.1 1.3 0.0 0.4 0.0 0.1 0.0 0.5 1.0 0.0 0.0 0.3 355.2 4.4 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 1.4 3.4 0.0 0.8 0.0 0.1 0.1 0.3 13.1 1.3 0.3 7.0 5.5 0.0 0.4 0.0 0.2 0.0 0.4 1.4 JAKMIP1 "FLJ31564, Gababrbp, JAMIP1, MARLIN1" ENSG00000152969 "Janus kinase and microtubule interacting protein 1" Q96N16 4 6026199-6200591 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 31.1;pituitary gland: 10.2;retina: 17.0" "Cell type enhanced" "Detected in some" "Astrocytes: 35.6;dendritic cells: 17.6;Excitatory neurons: 82.9;Inhibitory neurons: 53.6;Muller glia cells: 61.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 17 "gdT-cell: 25.3;MAIT T-cell: 11.2;memory CD4 T-cell: 11.2;memory CD8 T-cell: 22.6;naive CD8 T-cell: 10.1;T-reg: 36.7" "Lineage enriched" "Detected in many" 33 "T-cells: 36.7" "Cell line enhanced" "Detected in some" "Daudi: 15.8;JURKAT: 14.3;MOLT-4: 45.2;SCLC-21H: 18.6;U-266/70: 26.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044570 Uncertain NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 10: Brain - Neuronal signaling" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA044570: AB_2678995" "unprognostic (4.79e-2)" "unprognostic (3.46e-3)" "unprognostic (4.90e-2)" "unprognostic (1.73e-2)" "unprognostic (5.34e-2)" "unprognostic (3.86e-3)" "unprognostic (6.16e-2)" "unprognostic (6.69e-3)" "unprognostic (4.25e-4)" "unprognostic (7.14e-2)" "unprognostic (4.57e-3)" "unprognostic (1.13e-1)" "unprognostic (3.70e-8)" "unprognostic (1.85e-2)" "unprognostic (3.15e-1)" "unprognostic (4.23e-2)" "unprognostic (2.96e-3)" 0.3 4.8 21.4 1.0 31.1 1.3 0.1 5.0 30.4 0.2 0.1 1.0 0.2 0.1 0.1 0.3 0.2 0.5 0.1 21.6 22.0 0.2 0.3 0.9 3.0 9.0 13.5 0.5 0.6 0.0 10.2 0.0 12.8 4.2 0.2 17.0 0.7 0.1 0.1 0.1 1.1 0.2 7.1 2.6 0.6 5.2 16.2 0.3 0.7 0.0 0.6 0.7 0.3 20.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.8 0.0 0.0 2.6 0.0 0.0 0.0 0.0 8.7 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.3 0.0 0.0 0.0 0.4 45.2 0.0 3.4 0.0 2.6 2.3 0.0 0.7 0.0 0.0 18.6 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.3 4.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 25.3 0.0 11.2 0.3 11.2 22.6 0.0 0.2 0.8 10.1 0.1 1.1 0.0 0.1 36.7 5.4 21.4 31.1 5.0 30.4 21.6 22.0 9.0 13.5 12.8 7.1 16.2 20.3 0.2 0.0 0.0 35.6 0.8 0.0 0.0 0.0 0.0 1.5 0.2 0.1 0.8 0.0 0.0 0.0 2.1 0.0 17.6 0.0 0.0 0.0 1.5 0.1 0.2 0.1 0.0 0.4 82.9 0.0 0.0 0.5 2.6 0.8 0.0 0.2 0.0 0.0 0.1 3.3 53.6 0.0 0.0 1.3 0.5 2.4 0.0 0.5 0.0 7.5 0.3 61.2 12.3 7.1 3.1 0.1 0.0 0.0 2.3 1.3 0.0 0.1 0.0 5.4 0.0 0.0 0.2 0.9 4.6 0.0 0.1 0.0 16.2 0.4 0.0 0.0 JAKMIP2 "JAMIP2, KIAA0555" ENSG00000176049 "Janus kinase and microtubule interacting protein 2" Q96AA8 5 147585438-147782775 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.8" "Group enriched" "Detected in many" 6 "Astrocytes: 195.5;Excitatory neurons: 250.7;Horizontal cells: 85.8;Inhibitory neurons: 229.4;Oligodendrocyte precursor cells: 159.3;Oligodendrocytes: 198.5" "Cancer enriched" "Detected in some" 6 "glioma: 4.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 7.3;MAIT T-cell: 5.3;memory CD4 T-cell: 2.8;memory CD8 T-cell: 5.5;naive CD8 T-cell: 4.6;NK-cell: 7.0" "Group enriched" "Detected in many" 6 "NK-cells: 7.0;T-cells: 7.3" "Cell line enhanced" "Detected in many" "AF22: 19.9;Karpas-707: 47.5;RH-30: 47.8;RPMI-8226: 16.0;SCLC-21H: 22.4;SH-SY5Y: 15.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046929, HPA065023" Approved Supported "Golgi apparatus" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus" "HPA046929: AB_2679867, HPA065023: AB_2685407" "unprognostic (3.69e-2)" "unprognostic (4.22e-3)" "unprognostic (9.92e-2)" "unprognostic (3.58e-2)" "unprognostic (1.63e-1)" "unprognostic (3.29e-1)" "unprognostic (1.26e-1)" "unprognostic (6.71e-2)" "unprognostic (1.09e-1)" "unprognostic (3.69e-1)" "unprognostic (2.21e-4)" "unprognostic (1.28e-1)" "unprognostic (5.20e-8)" "unprognostic (1.54e-3)" "unprognostic (1.30e-1)" "unprognostic (1.33e-1)" "unprognostic (1.31e-1)" 0.2 3.3 11.4 1.0 12.5 0.5 0.1 24.8 14.3 0.5 0.1 2.2 0.4 1.0 0.2 1.3 0.1 1.4 0.4 11.4 12.1 0.3 2.6 2.0 0.9 11.7 11.8 0.1 0.8 1.0 8.3 0.1 12.4 0.6 0.5 5.3 0.2 0.4 0.0 0.3 0.6 1.5 10.4 0.8 1.8 2.9 13.0 7.0 0.1 1.6 0.9 0.7 0.2 16.6 0.0 0.0 19.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 8.1 0.0 0.0 4.8 0.1 0.0 0.0 0.0 3.1 6.9 2.0 0.0 0.0 0.3 0.0 5.7 2.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 47.5 0.0 0.1 5.1 0.0 11.4 0.1 0.1 2.0 47.8 16.0 0.0 0.1 22.4 15.4 0.0 0.3 0.1 2.5 0.0 0.0 0.0 3.5 4.0 0.0 1.1 3.3 2.0 4.6 8.9 0.0 0.0 0.0 0.0 0.4 7.3 0.0 5.3 0.7 2.8 5.5 0.1 0.3 0.7 4.6 0.5 7.0 0.2 1.1 1.3 1.5 11.4 12.5 24.8 14.3 11.4 12.1 11.7 11.8 12.4 10.4 13.0 16.6 0.2 0.0 1.5 195.5 1.5 0.0 0.0 0.0 0.0 23.2 0.0 0.1 0.7 0.0 1.3 0.0 2.1 0.0 13.3 0.0 0.0 0.8 11.3 0.2 0.5 0.3 1.2 3.0 250.7 0.0 0.0 1.2 0.5 0.1 29.1 10.3 0.7 3.1 1.3 85.8 229.4 0.8 0.0 0.9 0.0 8.4 0.0 4.2 0.0 11.2 0.4 24.4 23.7 159.3 198.5 0.2 0.0 0.0 3.1 0.0 0.1 0.1 1.5 7.9 0.0 0.4 0.7 7.8 2.0 0.1 0.1 0.3 13.8 18.9 0.0 0.3 JAML "AMICA, AMICA1, Gm638" ENSG00000160593 "Junction adhesion molecule like" Q86YT9 11 118193725-118225094 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 43.3;lymphoid tissue: 68.7" "Group enriched" "Detected in many" 4 "dendritic cells: 136.9;Kupffer cells: 125.8;Macrophages: 166.6;monocytes: 204.7;T-cells: 56.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "eosinophil: 3529.6" "Group enriched" "Detected in all" 5 "dendritic cells: 1017.6;granulocytes: 3529.6;monocytes: 1023.8" "Cell line enriched" "Detected in some" 5 "HMC-1: 28.0" "Region enriched" "Detected in many" 11 "cerebellum: 58.0" "HPA005854, HPA047919" Approved Supported "Nucleoplasm,Plasma membrane" NA NA 1400000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" Nucleoplasm "HPA005854: , HPA047919: AB_2680209" "unprognostic (3.91e-3)" "unprognostic (1.55e-3)" "unprognostic (3.00e-2)" "unprognostic (1.28e-3)" "unprognostic (2.87e-3)" "prognostic favorable (3.11e-4)" "unprognostic (2.80e-1)" "prognostic favorable (3.92e-4)" "unprognostic (1.14e-1)" "unprognostic (3.17e-1)" "unprognostic (8.69e-2)" "unprognostic (5.08e-1)" "unprognostic (6.43e-3)" "unprognostic (8.96e-2)" "unprognostic (3.12e-2)" "unprognostic (4.10e-2)" "unprognostic (1.58e-2)" 13.9 4.5 0.9 68.7 1.0 20.9 5.6 2.4 2.1 5.6 2.3 16.8 17.8 3.5 1.5 8.5 4.3 20.4 3.2 0.7 0.9 3.4 9.8 43.3 31.1 1.3 0.9 1.8 2.9 1.0 1.6 7.8 1.0 4.4 22.7 0.3 2.9 3.6 1.2 4.6 32.1 15.3 1.0 60.0 9.4 1.5 1.0 24.3 2.9 7.8 31.6 24.9 3.6 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 5.9 0.0 1.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.1 0.0 2.0 0.0 0.0 28.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.3 3.1 0.4 3.1 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.2 0.0 137.4 1023.8 3529.6 60.1 616.5 386.5 7.1 107.4 113.7 1017.6 2.9 124.7 103.1 2121.1 24.3 310.3 765.1 191.3 844.1 0.9 1.0 2.4 2.1 0.7 0.9 1.3 0.9 1.0 1.0 1.0 1.1 1.2 6.4 34.2 0.0 6.9 0.0 0.2 0.0 0.0 0.3 0.9 1.3 0.0 2.8 5.6 1.8 0.0 0.3 136.9 0.9 0.0 0.1 1.0 0.4 0.2 1.3 0.0 5.0 0.0 0.4 0.4 1.8 2.6 0.6 15.2 0.0 5.7 2.8 31.0 0.0 0.0 0.2 0.0 125.8 0.0 1.1 0.0 166.6 0.0 0.0 204.7 0.0 9.2 0.0 0.0 0.1 0.1 0.0 6.3 0.1 0.6 0.8 2.2 0.2 0.0 0.4 0.5 2.2 5.9 0.2 0.0 0.4 56.0 0.0 0.1 0.2 JHY "C11orf63, FLJ23554" ENSG00000109944 "Junctional cadherin complex regulator" Q6NUN7 11 122882683-122963862 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 35.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 12.8;Endometrial ciliated cells: 41.5;Glandular and luminal cells: 8.7;Proximal tubular cells: 12.0;Respiratory ciliated cells: 19.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "GAMG: 13.6" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA039612, HPA040344, HPA077658, HPA077748" Enhanced Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "Golgi apparatus" "HPA039612: AB_10674424, HPA040344: AB_2676931, HPA077658: AB_2732355, HPA077748: AB_2732360" "unprognostic (5.27e-2)" "unprognostic (1.12e-1)" "unprognostic (3.93e-2)" "prognostic favorable (7.94e-5)" "unprognostic (9.97e-5)" "unprognostic (1.64e-1)" "unprognostic (2.02e-3)" "unprognostic (1.94e-3)" "unprognostic (1.77e-1)" "unprognostic (1.49e-1)" "unprognostic (4.13e-2)" "unprognostic (2.97e-1)" "prognostic favorable (8.77e-4)" "unprognostic (6.46e-3)" "unprognostic (2.54e-1)" "prognostic unfavorable (2.58e-4)" "unprognostic (7.79e-2)" 6.0 1.8 1.7 2.2 2.7 1.1 3.6 3.4 2.4 3.1 17.3 3.5 1.5 2.1 2.7 1.8 7.4 2.6 2.2 1.8 3.8 7.8 0.4 4.5 2.2 4.1 5.4 3.2 2.8 5.6 4.8 1.3 3.8 3.5 1.7 1.6 1.4 2.5 0.2 1.9 1.9 2.0 3.8 2.5 2.0 35.7 3.2 3.2 5.1 0.8 2.0 2.6 1.8 3.6 2.8 3.9 2.2 0.1 0.6 0.4 0.7 5.9 6.8 2.5 1.1 0.3 10.3 0.1 1.5 9.1 13.6 2.4 2.7 1.4 1.1 9.5 2.8 0.1 1.8 0.1 0.9 1.7 4.7 2.8 7.4 0.4 0.6 6.3 3.8 4.1 0.0 0.1 2.0 1.8 0.1 0.6 0.3 8.2 3.5 1.0 0.0 1.3 7.0 3.2 5.8 4.2 7.1 3.9 2.6 2.8 4.7 0.6 1.2 7.9 1.0 0.2 4.8 0.1 0.0 0.1 2.1 2.1 5.3 0.5 0.3 0.1 1.3 0.1 1.8 1.1 1.3 1.7 2.4 0.6 0.9 1.0 0.4 2.4 0.1 0.6 0.3 0.5 1.7 2.7 3.4 2.4 1.8 3.8 4.1 5.4 3.8 3.8 3.2 3.6 4.4 12.8 4.4 0.0 1.1 0.0 0.0 0.0 0.0 0.0 3.3 3.2 0.0 0.0 7.4 5.5 0.0 0.2 2.2 0.0 3.9 5.5 0.0 41.5 3.1 1.1 0.0 0.0 0.0 1.4 0.9 2.2 0.0 8.7 0.0 2.9 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 2.6 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.7 0.0 0.0 12.0 19.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.3 1.8 1.3 0.0 0.0 JRK "jerky, JH8" ENSG00000234616 "Jrk helix-turn-helix protein" O75564 8 142657460-142681968 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052675 Approved "Nucleoplasm,Nucleoli,Nuclear bodies" No No "Cluster 46: Basophils - DNA binding" "Cluster 35: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Nucleoli" "Nuclear bodies" "HPA052675: AB_2681910" "unprognostic (3.65e-2)" "unprognostic (5.30e-2)" "unprognostic (9.67e-2)" "unprognostic (3.90e-3)" "unprognostic (1.27e-1)" "unprognostic (1.84e-2)" "unprognostic (6.58e-6)" "unprognostic (1.05e-1)" "unprognostic (3.87e-1)" "unprognostic (6.90e-2)" "unprognostic (1.84e-1)" "unprognostic (1.11e-1)" "unprognostic (7.50e-2)" "unprognostic (2.07e-1)" "unprognostic (2.53e-1)" "unprognostic (1.22e-2)" "unprognostic (1.69e-2)" 3.7 4.5 5.9 4.1 6.1 2.1 4.0 7.9 7.4 7.4 4.0 5.9 3.0 6.7 3.4 4.9 5.5 2.5 5.9 5.8 4.7 7.9 4.0 3.9 5.4 6.2 5.2 8.5 5.4 4.6 6.4 3.0 5.5 6.2 2.8 3.8 4.7 4.0 7.5 6.0 5.3 3.7 4.3 7.2 5.7 6.6 6.2 5.1 6.9 4.7 5.9 5.7 4.7 6.8 6.5 6.9 8.0 6.4 7.6 10.8 4.8 10.4 4.2 11.9 6.8 6.3 13.1 11.0 4.1 8.2 8.2 8.7 7.0 6.2 6.0 8.5 12.0 11.2 25.3 7.2 3.1 8.6 7.5 7.2 5.4 7.6 4.3 6.0 6.8 13.1 12.0 4.8 10.1 11.1 10.1 4.8 6.8 4.6 9.6 13.1 5.0 6.2 4.1 11.1 14.5 9.6 18.1 7.3 4.3 5.0 7.3 5.2 8.1 9.1 19.5 9.1 5.5 6.3 7.6 6.3 6.9 10.7 9.0 1.0 0.7 0.9 0.9 0.5 0.5 0.4 1.0 0.9 0.7 1.2 1.3 1.0 0.8 0.6 0.2 0.6 0.6 0.4 5.9 6.1 7.9 7.4 5.8 4.7 6.2 5.2 5.5 4.3 6.2 6.8 3.5 6.4 1.1 8.5 4.8 0.0 2.5 0.0 2.2 14.7 4.5 3.3 11.5 4.3 0.6 7.3 20.9 4.4 8.6 3.2 3.9 2.8 1.9 1.4 4.9 6.5 9.1 12.0 11.3 2.5 2.7 3.7 6.6 2.1 1.3 15.5 8.2 2.6 3.0 10.1 11.0 3.1 0.0 6.6 0.0 2.2 11.5 3.4 0.0 8.4 4.5 4.4 12.3 9.5 9.5 5.6 1.4 11.7 4.3 3.7 2.7 2.7 0.7 10.0 0.0 5.8 4.8 9.1 19.4 3.2 0.0 2.2 2.5 6.8 4.2 4.5 JSRP1 "FLJ32416, JP-45" ENSG00000167476 "Junctional sarcoplasmic reticulum protein 1" Q96MG2 19 2252252-2269759 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "skeletal muscle: 335.4" "Cell type enhanced" "Detected in many" "B-cells: 31.7;Melanocytes: 46.2;Plasma cells: 139.4;Skeletal myocytes: 132.6" "Cancer enriched" "Detected in many" 4 "endometrial cancer: 11.0" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 10 "naive B-cell: 2.6" "Lineage enriched" "Detected in single" 10 "B-cells: 2.6" "Cell line enhanced" "Detected in some" "Karpas-707: 164.1;RPMI-8226: 109.8;U-266/70: 444.1;U-266/84: 57.8" "Group enriched" "Detected in many" 6 "amygdala: 8.4;basal ganglia: 11.6;cerebral cortex: 9.9;hippocampal formation: 4.4;white matter: 5.1" "Not detected" "Not detected" HPA044741 Enhanced Approved "Endoplasmic reticulum" NA NA 13000 "Cluster 24: B-cells - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "HPA044741: AB_10794295" "unprognostic (9.41e-3)" "unprognostic (1.52e-2)" "unprognostic (1.39e-1)" "unprognostic (5.85e-2)" "unprognostic (2.15e-1)" "unprognostic (9.69e-2)" "unprognostic (1.58e-2)" "unprognostic (4.64e-2)" "unprognostic (4.27e-2)" "unprognostic (1.80e-2)" "unprognostic (2.44e-2)" "unprognostic (1.87e-2)" "unprognostic (8.64e-5)" "unprognostic (3.63e-1)" "unprognostic (4.43e-1)" "unprognostic (2.07e-1)" "unprognostic (2.71e-1)" 0.2 0.1 0.4 0.9 0.4 0.4 0.4 0.4 0.4 0.3 0.2 1.5 2.9 0.1 0.0 0.3 0.3 0.1 0.0 0.3 0.4 0.6 0.3 0.7 0.5 0.3 0.3 0.1 0.5 0.0 0.3 0.0 0.3 1.9 0.1 0.0 8.9 0.0 335.4 0.3 1.4 0.0 0.3 5.4 1.7 1.9 0.5 0.1 0.6 18.6 0.6 0.2 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.4 26.8 0.0 0.0 0.2 0.0 0.0 0.0 46.6 0.1 0.0 0.0 1.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 164.1 7.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 26.7 109.8 0.0 0.0 0.1 0.6 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 444.1 57.8 2.4 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.2 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.4 0.4 0.4 0.3 0.4 0.3 0.3 0.3 0.3 0.5 0.3 0.1 0.0 5.3 0.0 31.7 0.5 0.3 0.2 0.6 0.8 0.6 0.4 0.6 1.5 0.1 0.0 2.1 0.2 0.7 1.7 0.0 1.8 19.0 0.7 0.3 0.3 5.4 1.3 0.2 1.0 0.6 1.1 1.5 1.1 6.3 2.9 0.7 0.6 0.5 0.0 0.1 2.3 2.0 1.3 2.2 18.2 0.6 1.1 46.2 0.0 0.0 0.5 1.0 0.0 0.1 1.0 0.3 0.0 139.4 0.3 0.6 0.4 1.7 0.5 0.0 132.6 0.6 7.6 1.9 0.2 1.0 0.3 5.0 0.5 0.7 0.2 KANSL1L "C2orf67, FLJ23861, FLJ32349, KIAA1267L, MSL1v2" ENSG00000144445 "KAT8 regulatory NSL complex subunit 1 like" A0AUZ9 2 210021421-210171409 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "parathyroid gland: 198.9" "Cell type enhanced" "Detected in many" "Astrocytes: 113.6;Inhibitory neurons: 117.9;Microglial cells: 103.0;Oligodendrocyte precursor cells: 190.5;Oligodendrocytes: 158.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043102, HPA046790" Uncertain Approved Cytosol NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 68: Oligodendrocytes - Mixed function" Cytosol "HPA043102: AB_2678316, HPA046790: AB_2679808" "unprognostic (3.85e-2)" "unprognostic (2.37e-1)" "unprognostic (1.04e-1)" "unprognostic (7.55e-3)" "unprognostic (1.45e-2)" "unprognostic (2.55e-3)" "unprognostic (5.52e-2)" "unprognostic (1.46e-1)" "unprognostic (5.99e-3)" "unprognostic (4.65e-2)" "unprognostic (5.89e-3)" "unprognostic (5.75e-2)" "unprognostic (5.95e-3)" "unprognostic (7.44e-2)" "unprognostic (4.60e-2)" "unprognostic (3.21e-2)" "unprognostic (1.30e-3)" 11.6 8.3 10.7 6.2 13.5 5.5 10.3 14.3 9.2 14.4 8.9 9.9 6.5 18.7 17.4 6.9 13.2 15.7 9.7 9.7 11.7 22.7 9.4 11.9 6.7 11.3 12.6 28.5 15.2 198.9 10.0 8.3 12.0 16.9 6.8 12.5 10.0 17.0 12.1 13.3 6.7 13.3 10.6 6.3 12.4 25.3 10.8 26.7 19.7 18.4 5.2 13.6 11.3 17.7 2.7 1.4 14.5 6.1 11.7 8.7 4.0 4.1 5.4 2.7 7.4 2.7 10.9 7.9 5.5 2.8 6.5 3.8 3.4 1.5 4.3 3.4 2.7 6.3 6.1 4.6 7.3 7.4 4.3 5.5 6.5 2.7 1.9 11.5 6.1 7.2 4.5 7.1 4.1 2.7 8.5 19.7 8.4 4.8 1.9 6.1 3.9 6.1 16.0 4.0 9.0 8.5 3.7 2.3 2.9 14.4 2.5 16.1 4.9 5.3 4.3 1.9 3.1 4.9 2.2 7.7 7.0 3.5 7.1 0.2 0.3 0.5 0.2 0.4 0.2 0.1 0.2 0.2 0.4 0.3 0.3 0.3 0.4 0.6 0.1 0.3 0.1 0.1 10.7 13.5 14.3 9.2 9.7 11.7 11.3 12.6 12.0 10.6 10.8 17.7 12.8 28.9 20.1 113.6 4.6 7.4 6.7 3.9 11.4 8.6 5.4 6.7 9.2 20.0 6.6 31.3 14.6 1.7 1.5 2.3 3.9 13.2 30.3 22.3 17.0 8.8 6.0 4.6 79.0 5.5 0.9 14.2 9.2 14.7 10.8 23.6 6.4 7.4 2.7 5.0 117.9 3.2 8.2 2.8 6.7 22.2 14.6 8.5 7.2 103.0 5.5 9.6 4.1 190.5 158.9 6.7 4.7 30.1 3.0 7.0 2.0 15.8 36.0 8.7 13.1 31.1 15.6 44.9 7.8 5.5 11.1 1.9 2.7 6.6 2.8 4.1 KARS1 "DFNB89, KARS, KARS2" ENSG00000065427 "Lysyl-tRNA synthetase 1" Q15046 16 75627474-75648643 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase, Transferase" "Charcot-Marie-Tooth disease, Deafness, Disease variant, Neurodegeneration, Neuropathy, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 7 "Cardiomyocytes: 90.7;Cytotrophoblasts: 122.7;Extravillous trophoblasts: 143.3;Hofbauer cells: 89.5;Syncytiotrophoblasts: 110.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041345, HPA041550" Enhanced Supported "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 82000 "Cluster 27: Non-specific - Gene expression" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Cytosol "Plasma membrane" "HPA041345: AB_10795589, HPA041550: AB_10794520" "unprognostic (1.56e-1)" "unprognostic (7.93e-2)" "unprognostic (3.36e-2)" "unprognostic (1.02e-2)" "unprognostic (5.39e-2)" "prognostic unfavorable (8.84e-6)" "unprognostic (6.24e-3)" "unprognostic (8.97e-3)" "unprognostic (1.18e-1)" "unprognostic (9.11e-3)" "unprognostic (8.71e-3)" "unprognostic (8.46e-2)" "unprognostic (7.86e-2)" "unprognostic (1.56e-1)" "unprognostic (1.03e-1)" "unprognostic (3.07e-2)" "unprognostic (2.13e-1)" 68.5 49.6 45.5 71.6 47.3 86.1 83.0 46.9 63.2 60.3 50.6 75.8 62.4 53.9 75.1 72.5 69.5 50.4 96.0 45.6 48.3 72.2 76.8 53.1 88.3 46.9 47.5 74.9 86.5 76.7 51.5 62.2 46.8 55.2 85.6 69.6 79.6 60.6 213.4 67.3 62.6 69.6 46.8 57.6 66.2 98.9 47.4 96.6 65.3 186.8 107.8 92.1 55.0 48.1 164.2 187.0 133.5 185.4 140.1 140.3 262.4 135.0 164.9 290.2 217.0 332.8 209.0 292.4 145.4 180.8 138.4 229.4 272.0 246.7 314.4 86.0 139.8 161.4 153.1 348.5 255.8 245.5 174.1 166.4 173.8 257.4 414.6 147.7 240.0 253.5 273.4 68.5 222.5 378.0 254.1 262.2 284.3 238.4 135.9 329.2 120.0 358.4 235.4 136.3 200.2 162.9 339.5 122.8 152.2 144.8 166.1 229.2 133.8 159.8 164.9 123.6 196.7 145.1 178.6 696.6 139.5 206.5 199.7 88.6 112.7 130.0 110.7 155.7 202.6 109.5 137.1 132.0 135.7 91.6 126.6 117.1 24.9 127.6 163.1 85.7 155.5 160.5 45.5 47.3 46.9 63.2 45.6 48.3 46.9 47.5 46.8 46.8 47.4 48.1 14.2 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 90.7 0.0 0.0 0.0 0.0 122.7 10.1 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 143.3 14.4 0.0 0.0 0.0 0.0 0.0 0.0 89.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 110.0 2.1 0.0 0.0 0.0 KCMF1 "DEBT91, DKFZP434L1021, PCMF, ZZZ1" ENSG00000176407 "Potassium channel modulatory factor 1" Q9P0J7 2 84971093-85059472 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030383, HPA030384" Enhanced Enhanced Nucleoplasm,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" Cytosol Nucleoplasm "HPA030383: AB_10599977, HPA030384: AB_10601230" "unprognostic (8.01e-2)" "unprognostic (1.98e-2)" "unprognostic (9.95e-2)" "unprognostic (7.42e-3)" "unprognostic (1.24e-2)" "unprognostic (8.54e-2)" "prognostic unfavorable (2.33e-7)" "unprognostic (5.68e-3)" "unprognostic (1.43e-1)" "unprognostic (9.81e-2)" "prognostic unfavorable (6.10e-5)" "unprognostic (4.98e-2)" "prognostic unfavorable (4.18e-6)" "unprognostic (6.11e-2)" "unprognostic (2.66e-1)" "unprognostic (4.42e-1)" "unprognostic (1.01e-1)" 39.7 24.0 23.4 34.0 22.2 60.8 33.8 21.3 30.2 28.1 20.4 46.7 34.8 29.2 39.7 58.3 27.6 29.5 44.1 25.6 24.1 33.1 45.0 31.9 36.1 25.2 26.5 24.7 80.0 39.2 20.8 33.0 24.8 27.9 46.4 32.4 36.8 31.8 140.0 35.2 36.2 40.5 24.8 28.3 33.5 69.0 27.3 37.0 40.4 71.7 52.3 37.7 36.1 22.1 102.3 76.4 66.7 51.8 69.0 66.2 114.5 106.0 96.0 97.4 64.6 93.8 104.5 110.9 107.2 141.6 97.0 65.1 52.7 100.6 127.8 87.6 37.9 69.8 55.9 97.3 134.7 77.9 63.9 69.0 155.7 95.7 262.5 86.4 74.7 57.2 71.3 83.1 98.4 91.5 76.9 42.6 74.9 125.5 64.1 55.4 94.7 68.5 88.3 85.8 64.8 48.9 61.0 76.0 101.8 76.4 35.3 48.1 66.2 98.9 99.2 93.5 111.8 99.1 130.9 110.4 74.5 55.7 75.8 3.1 1.6 5.4 2.7 1.4 2.1 2.3 1.9 2.0 1.4 3.1 1.6 1.8 4.5 1.9 2.2 2.6 6.0 1.0 23.4 22.2 21.3 30.2 25.6 24.1 25.2 26.5 24.8 24.8 27.3 22.1 45.5 32.1 26.6 25.5 29.6 70.9 92.9 32.7 24.5 31.8 42.8 34.3 51.4 21.5 33.2 12.9 14.6 23.6 42.0 56.2 25.4 34.8 85.2 55.3 33.8 33.1 19.2 29.0 47.9 53.4 32.0 31.9 18.8 80.5 17.7 30.9 24.3 32.9 20.1 72.3 47.4 29.0 20.3 33.3 61.1 127.7 25.7 34.7 26.6 51.5 36.8 37.5 21.6 45.8 36.6 61.2 40.8 29.0 27.6 107.6 44.8 30.7 22.5 27.5 26.3 48.2 47.2 44.9 24.6 34.4 79.0 40.8 32.1 27.1 33.7 135.5 KCNA2 "HK4, Kv1.2" ENSG00000177301 "Potassium voltage-gated channel subfamily A member 2" P16389 1 110519837-110631474 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "brain: 81.3" "Group enriched" "Detected in some" 4 "Astrocytes: 49.9;Excitatory neurons: 36.7;Inhibitory neurons: 37.1;Muller glia cells: 19.8;Oligodendrocyte precursor cells: 36.2" "Cancer enhanced" "Detected in some" "glioma: 1.2;testis cancer: 1.0" "Region enhanced" "Detected in many" "cerebral cortex: 81.3" "Immune cell enhanced" "Detected in single" "T-reg: 1.3" "Lineage enriched" "Detected in single" 8 "T-cells: 1.3" "Cell line enhanced" "Detected in some" "Karpas-707: 4.8;SCLC-21H: 1.4;U-2 OS: 1.2;U-266/70: 1.9;U-266/84: 3.1;WM-115: 1.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB001976 Enhanced NA NA "Cluster 35: T-regs - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB001976: " "unprognostic (1.84e-2)" "unprognostic (9.70e-3)" "unprognostic (1.97e-1)" "unprognostic (2.98e-1)" "unprognostic (7.17e-3)" "unprognostic (6.68e-3)" "unprognostic (5.05e-3)" "unprognostic (2.02e-1)" "unprognostic (1.29e-1)" "unprognostic (4.50e-3)" "unprognostic (3.08e-3)" "unprognostic (2.93e-4)" "unprognostic (2.15e-1)" "unprognostic (3.55e-1)" "unprognostic (6.41e-2)" "unprognostic (2.83e-1)" 1.3 0.3 5.0 0.7 7.4 0.0 0.6 11.1 81.3 0.2 0.0 1.6 0.4 0.1 0.3 0.4 0.1 0.3 0.7 4.5 12.5 0.1 0.0 0.1 0.6 28.0 7.5 0.1 0.8 0.0 2.1 0.0 32.0 0.5 0.5 9.6 0.5 0.8 1.0 0.5 0.6 0.4 0.1 0.3 0.7 0.9 27.1 3.0 2.3 2.1 1.5 0.3 0.3 20.7 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.8 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.3 0.0 0.7 0.0 0.0 1.4 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 1.2 0.0 0.0 1.9 3.1 0.1 0.0 0.0 1.4 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.5 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 5.0 7.4 11.1 81.3 4.5 12.5 28.0 7.5 32.0 0.1 27.1 20.7 0.1 0.0 0.0 49.9 0.2 0.0 0.0 0.0 0.0 7.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.5 0.2 0.0 0.0 36.7 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 37.1 0.0 0.0 0.0 0.0 1.1 0.0 0.9 0.0 8.4 0.0 19.8 0.0 36.2 6.8 0.0 0.0 5.3 1.6 0.0 0.0 0.0 0.0 4.2 0.0 0.4 1.0 0.0 2.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 KCNB2 Kv2.2 ENSG00000182674 "Potassium voltage-gated channel subfamily B member 2" Q92953 8 72537225-72938349 "FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.6;lymphoid tissue: 2.3;retina: 4.6" "Group enriched" "Detected in some" 14 "Cone photoreceptor cells: 264.8;Excitatory neurons: 279.1;Inhibitory neurons: 241.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HaCaT: 1.4;HDLM-2: 1.4;HEK 293: 3.4;SCLC-21H: 2.7" "Low region specificity" "Detected in many" HPA065970 Approved "Nucleoli,Plasma membrane,Midbody" Yes NA "Cluster 58: Brain - Synaptic function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Nucleoli, Midbody" "HPA065970: AB_2685591" "unprognostic (9.87e-3)" "unprognostic (1.71e-1)" "unprognostic (7.57e-2)" "unprognostic (1.10e-3)" "unprognostic (1.22e-1)" "unprognostic (1.34e-1)" "unprognostic (1.44e-2)" "unprognostic (2.72e-1)" "unprognostic (6.93e-5)" "unprognostic (5.53e-3)" "unprognostic (3.30e-2)" "unprognostic (1.62e-1)" "unprognostic (3.35e-2)" "unprognostic (3.26e-1)" 0.1 0.4 1.7 0.0 2.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.4 0.0 0.0 2.4 2.2 0.0 0.0 0.0 0.0 1.0 2.6 0.0 0.5 0.0 1.1 0.0 0.4 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.3 0.0 1.3 2.3 0.4 0.3 1.5 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 1.4 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 2.0 0.0 1.4 2.4 2.2 1.0 2.6 0.4 1.3 1.5 0.0 0.1 0.0 0.0 4.6 0.0 0.0 0.0 0.0 1.2 17.4 0.0 0.0 0.3 0.0 0.0 1.8 264.8 0.0 0.0 0.1 0.0 0.0 4.0 0.0 0.0 0.1 17.9 0.0 279.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 241.2 0.6 0.0 0.0 0.0 6.8 1.2 0.0 0.0 3.7 0.0 0.7 0.0 11.6 4.7 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.0 4.0 0.0 0.1 0.1 0.4 1.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 KCNH6 "erg2, HERG2, Kv11.2" ENSG00000173826 "Potassium voltage-gated channel subfamily H member 6" Q9H252 17 63523334-63548977 "FDA approved drug targets, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 4.8;kidney: 7.0;pituitary gland: 5.3;prostate: 3.9;retina: 4.4" "Group enriched" "Detected in some" 8 "Bipolar cells: 44.8;Cardiomyocytes: 25.6;Cone photoreceptor cells: 31.3;Enteroendocrine cells: 34.6;Proximal enterocytes: 40.3;Proximal tubular cells: 14.1" "Cancer enhanced" "Detected in some" "prostate cancer: 5.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "SCLC-21H: 3.3;SH-SY5Y: 1.1" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "medulla oblongata: 1.1;olfactory bulb: 2.4;spinal cord: 2.5" HPA061704 Approved NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA061704: " "unprognostic (8.00e-2)" "unprognostic (1.80e-1)" "unprognostic (5.46e-2)" "unprognostic (5.68e-2)" "unprognostic (5.98e-5)" "unprognostic (3.39e-1)" "unprognostic (1.15e-1)" "unprognostic (3.03e-1)" "unprognostic (1.28e-2)" "unprognostic (3.25e-1)" "unprognostic (1.74e-3)" "unprognostic (3.95e-1)" "unprognostic (1.19e-1)" "unprognostic (9.80e-2)" "unprognostic (3.66e-1)" "unprognostic (8.05e-2)" "unprognostic (9.15e-2)" 0.0 0.1 0.9 0.0 1.1 0.2 0.0 0.9 1.1 0.0 0.3 0.2 2.2 0.0 0.0 0.0 0.1 0.0 0.0 0.6 1.6 7.0 0.0 0.3 0.0 1.6 1.5 0.0 1.3 0.0 5.3 0.1 1.7 3.9 0.2 4.4 0.0 0.0 0.1 0.1 4.8 0.0 1.1 0.1 0.8 1.2 1.5 0.7 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.3 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 1.1 0.9 1.1 0.6 1.6 1.6 1.5 1.7 1.1 1.5 1.1 0.0 0.0 0.0 0.3 0.0 0.3 0.2 0.0 0.0 44.8 0.0 0.3 25.6 0.0 0.0 0.0 31.3 0.0 0.0 0.1 0.0 0.0 3.0 0.6 0.1 1.3 34.6 0.0 1.1 0.0 0.0 0.8 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.9 3.8 0.0 0.0 0.0 3.4 0.0 0.1 1.8 0.0 0.0 1.1 0.0 0.5 0.1 0.1 1.2 0.0 0.0 1.4 40.3 14.1 0.0 3.1 0.0 0.2 1.0 0.0 0.7 0.0 0.1 0.1 0.1 0.0 0.8 0.1 KCNJ16 "BIR9, Kir5.1" ENSG00000153822 "Potassium inwardly rectifying channel subfamily J member 16" Q9NPI9 17 70053429-70135608 "Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 196.1;parathyroid gland: 269.2;thyroid gland: 139.4" "Cell type enhanced" "Detected in some" "Cholangiocytes: 54.3;Collecting duct cells: 244.6;Distal tubular cells: 41.1;Oligodendrocyte precursor cells: 54.8;Proximal tubular cells: 95.2" "Group enriched" "Detected in many" 10 "renal cancer: 37.2;thyroid cancer: 80.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "neutrophil: 1.6" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.6" "Cell line enriched" "Detected in some" 22 "RPTEC TERT1: 279.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059563 Approved Uncertain Vesicles NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA059563: AB_2684065" "unprognostic (2.81e-3)" "unprognostic (2.10e-1)" "unprognostic (6.06e-2)" "unprognostic (1.20e-3)" "unprognostic (1.16e-1)" "unprognostic (7.53e-2)" "unprognostic (4.38e-4)" "unprognostic (1.02e-1)" "unprognostic (1.23e-1)" "unprognostic (1.52e-2)" "unprognostic (3.35e-1)" "unprognostic (1.34e-1)" "prognostic favorable (9.61e-7)" "unprognostic (2.74e-1)" "unprognostic (1.39e-1)" "prognostic favorable (6.58e-4)" "unprognostic (3.88e-1)" 0.3 0.4 10.0 0.4 14.0 0.6 3.8 22.7 11.6 0.1 2.3 0.6 0.7 0.5 15.9 0.3 5.1 18.8 0.6 6.8 39.5 196.1 1.3 0.9 0.8 39.7 37.6 0.2 44.2 269.2 1.0 0.9 25.7 0.2 0.2 1.2 11.8 21.7 0.3 0.8 2.5 0.0 29.9 1.5 23.4 1.7 27.3 0.2 139.4 0.0 0.1 0.0 0.0 20.8 0.1 0.4 0.2 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.6 0.0 1.2 0.5 0.0 0.2 0.0 0.0 0.0 0.2 1.2 0.8 0.3 0.3 0.0 0.0 0.3 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 1.1 0.2 0.0 0.0 0.0 0.3 0.6 0.1 0.0 12.7 0.0 0.0 279.8 0.2 0.3 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.4 0.0 0.3 0.1 0.1 0.0 0.2 0.8 0.2 0.0 0.1 0.0 0.0 0.2 0.3 0.0 0.3 0.3 0.3 0.1 0.0 0.3 0.2 0.2 1.6 0.3 0.0 0.1 0.3 0.1 10.0 14.0 22.7 11.6 6.8 39.5 39.7 37.6 25.7 29.9 27.3 20.8 0.1 0.0 0.0 12.1 0.0 0.0 0.0 2.7 0.0 0.0 2.3 1.1 0.4 54.3 2.6 244.6 0.0 0.0 0.0 0.0 41.1 12.4 0.0 2.8 0.1 0.0 0.0 0.0 1.0 1.4 0.0 0.3 3.1 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 1.0 0.0 0.0 0.0 0.0 0.0 54.8 0.1 6.0 0.0 0.0 0.0 0.0 1.0 95.2 9.8 0.0 0.0 0.2 0.3 0.2 0.6 0.0 0.0 0.0 0.6 0.2 0.0 0.0 KCNK1 "DPK, K2p1.1, TWIK-1" ENSG00000135750 "Potassium two pore domain channel subfamily K member 1" O00180 1 233614106-233672514 "Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 58.0" "Cell type enhanced" "Detected in many" "Excitatory neurons: 157.8;Horizontal cells: 200.2;Prostatic glandular cells: 222.9;Urothelial cells: 371.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 69 "plasmacytoid DC: 6.9" "Lineage enriched" "Detected in single" 69 "dendritic cells: 6.9" "Cell line enhanced" "Detected in many" "HeLa: 64.7;SCLC-21H: 62.5;U-266/70: 137.3;U-266/84: 134.7" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 117.0" "HPA016049, CAB022588" Approved Approved Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 45: Intestine - Brush border" "Cluster 29: U-266 - Adaptive immune response" "Cluster 22: Epithelial cell types - Mixed function" Vesicles "CAB022588: , HPA016049: AB_1855571" "unprognostic (7.06e-3)" "unprognostic (1.76e-1)" "unprognostic (4.64e-2)" "unprognostic (7.46e-2)" "unprognostic (9.15e-2)" "unprognostic (1.27e-1)" "prognostic favorable (3.84e-4)" "unprognostic (4.32e-2)" "unprognostic (6.15e-2)" "unprognostic (1.34e-2)" "prognostic unfavorable (7.29e-4)" "unprognostic (1.10e-1)" "prognostic unfavorable (8.69e-8)" "unprognostic (1.62e-1)" "unprognostic (2.76e-1)" "unprognostic (1.77e-1)" "unprognostic (1.97e-1)" 3.9 4.1 17.7 2.9 19.8 0.3 5.7 58.0 28.4 7.8 50.4 15.7 16.9 6.1 30.9 20.9 10.9 12.1 41.0 24.3 13.7 9.2 12.1 4.4 1.0 23.5 17.8 7.3 5.5 16.2 22.2 6.8 24.1 6.4 13.9 18.5 15.1 11.3 0.4 13.3 12.6 3.8 15.4 0.9 38.1 0.9 16.3 0.5 7.2 0.9 4.4 11.5 14.4 21.3 33.2 18.3 0.1 0.0 0.0 0.0 50.2 8.8 0.0 0.0 0.0 0.0 52.9 0.0 20.7 6.8 7.3 47.1 8.9 15.2 0.0 0.1 15.8 0.0 64.7 0.0 0.5 0.0 1.8 3.9 17.0 0.0 12.4 1.1 0.2 17.7 7.9 15.0 0.0 12.6 12.2 0.1 10.9 38.5 41.0 0.0 2.7 3.7 16.0 28.4 62.5 11.8 33.5 14.3 0.0 1.0 4.1 0.1 0.0 0.1 25.8 0.0 1.0 137.3 134.7 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 17.7 19.8 58.0 28.4 24.3 13.7 23.5 17.8 24.1 15.4 16.3 21.3 0.4 9.6 22.9 5.9 0.6 63.3 136.7 32.6 3.4 2.9 23.0 6.0 54.7 12.8 44.6 18.4 4.2 0.5 3.0 91.0 1.9 29.2 1.1 52.7 26.4 3.5 29.3 0.0 157.8 48.3 14.0 31.2 50.4 89.3 0.0 15.0 0.0 8.9 0.6 200.2 61.0 56.3 24.4 0.3 4.4 0.2 1.5 1.0 10.6 12.2 0.0 72.6 0.0 36.2 73.2 96.3 82.4 0.0 0.2 222.9 10.6 8.8 42.9 5.1 0.0 2.3 6.9 0.6 3.2 19.1 47.6 0.8 1.4 0.5 31.2 371.6 KCNS1 Kv9.1 ENSG00000124134 "Potassium voltage-gated channel modifier subfamily S member 1" Q96KK3 20 45091214-45101127 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "brain: 22.8" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 2.0;Cholangiocytes: 7.2;Collecting duct cells: 1.8;Excitatory neurons: 6.2" "Cancer enriched" "Detected in many" 5 "cervical cancer: 6.1" "Region enhanced" "Detected in many" "cerebral cortex: 22.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HBF TERT88: 1.3;HHSteC: 2.1;hTEC/SVTERT24-B: 1.0;THP-1: 1.8;U-87 MG: 2.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 43: THP-1 - Innate immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (2.46e-2)" "unprognostic (2.95e-3)" "unprognostic (2.03e-1)" "unprognostic (3.11e-4)" "unprognostic (8.91e-3)" "unprognostic (6.01e-3)" "unprognostic (7.47e-2)" "unprognostic (8.94e-2)" "unprognostic (4.37e-2)" "prognostic unfavorable (6.45e-4)" "unprognostic (6.74e-2)" "unprognostic (4.65e-2)" "unprognostic (6.35e-2)" "unprognostic (5.62e-2)" "unprognostic (3.06e-2)" "unprognostic (1.15e-1)" "unprognostic (1.39e-1)" 0.0 0.4 0.9 0.1 2.9 0.1 0.2 0.0 22.8 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.4 0.1 4.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.1 1.5 2.8 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.1 0.3 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.1 0.1 0.4 0.4 0.1 0.1 0.6 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.3 0.0 1.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.8 0.0 0.9 0.2 0.0 1.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.9 2.9 0.0 22.8 4.1 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 2.0 0.3 0.0 0.4 0.1 0.1 0.0 0.0 0.3 0.1 1.1 7.2 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 6.2 0.2 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.1 0.0 0.0 0.1 0.1 KCP "CRIM2, FLJ33365, NET67" ENSG00000135253 "Kielin cysteine rich BMP regulator" Q6ZWJ8 7 128862042-128910719 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "kidney: 17.0" "Cell type enhanced" "Detected in many" "Collecting duct cells: 53.3;Early spermatids: 23.1;Late spermatids: 28.7;Proximal enterocytes: 55.9" "Cancer enhanced" "Detected in many" "renal cancer: 5.5" "Region enriched" "Detected in single" 5 "cerebellum: 1.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 9.3;HMC-1: 5.1;U-87 MG: 2.2" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 45: Enterocytes - Digestion" "unprognostic (6.12e-2)" "unprognostic (5.49e-2)" "unprognostic (1.45e-3)" "unprognostic (6.33e-3)" "unprognostic (2.14e-1)" "unprognostic (5.24e-3)" "unprognostic (2.01e-3)" "unprognostic (3.25e-3)" "unprognostic (9.59e-2)" "unprognostic (1.52e-1)" "unprognostic (2.20e-3)" "unprognostic (6.46e-2)" "unprognostic (1.93e-1)" "unprognostic (1.46e-1)" "unprognostic (1.28e-1)" "unprognostic (4.84e-2)" "unprognostic (7.64e-3)" 1.5 0.1 0.0 0.2 0.0 0.0 0.3 1.8 0.1 0.9 0.0 0.1 0.4 0.0 0.0 1.6 0.5 1.0 0.1 0.0 0.0 17.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.3 0.0 0.0 0.4 2.2 0.1 0.2 1.0 0.0 0.0 0.2 0.6 0.2 0.3 0.0 0.5 0.2 0.0 0.2 0.6 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 9.3 0.2 1.3 0.0 0.1 0.6 0.0 0.0 0.0 1.3 0.0 0.6 0.0 0.8 0.1 0.0 5.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.1 0.0 1.2 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.6 0.2 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.1 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.9 12.8 3.4 0.3 1.9 0.0 0.9 0.0 1.2 3.0 0.6 0.9 0.8 0.0 3.7 53.3 2.1 0.2 0.9 2.1 0.0 0.3 23.1 2.1 1.3 0.8 2.4 0.0 0.4 0.2 4.1 2.0 3.1 2.9 2.5 0.2 2.2 0.3 1.0 3.3 2.6 5.3 0.0 1.3 0.0 28.7 1.2 3.1 0.0 0.0 0.1 0.4 2.1 0.0 0.2 4.3 1.9 0.4 1.9 0.3 55.9 6.4 0.0 1.3 0.0 7.3 1.7 6.3 3.7 2.1 0.0 1.4 2.2 0.5 9.2 4.1 KDM1A "AOF2, BHC110, KDM1, KIAA0601, LSD1" ENSG00000004487 "Lysine demethylase 1A" O60341 1 23019443-23083689 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Developmental protein, Oxidoreductase, Repressor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 131.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005884, HPA053660" Supported Supported Nucleoplasm,Cytosol "Intracellular and membrane" NA NA 7700 "Cluster 37: B-cells - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 14: REH - Unknown function" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm Cytosol "CAB005884: AB_443964, HPA053660: AB_2682220" "unprognostic (1.03e-1)" "unprognostic (1.17e-1)" "prognostic favorable (6.31e-4)" "unprognostic (1.50e-1)" "unprognostic (6.83e-2)" "unprognostic (3.95e-2)" "prognostic unfavorable (4.47e-12)" "unprognostic (1.80e-2)" "unprognostic (1.99e-2)" "unprognostic (9.41e-2)" "unprognostic (3.34e-3)" "unprognostic (2.13e-1)" "unprognostic (2.61e-1)" "unprognostic (1.41e-1)" "unprognostic (3.73e-2)" "unprognostic (7.74e-2)" "unprognostic (1.39e-1)" 25.7 30.8 24.7 23.5 25.8 48.1 30.6 26.5 27.0 33.1 20.4 31.6 26.4 36.0 46.9 35.0 34.2 25.3 26.1 25.3 28.2 24.7 22.3 24.5 34.7 19.8 22.0 41.4 36.2 51.2 41.5 31.5 21.0 32.2 33.8 30.9 36.6 29.4 47.3 38.2 29.2 30.1 21.2 25.2 29.3 86.9 27.4 55.8 28.5 34.0 37.2 34.6 31.5 21.8 128.1 64.7 180.8 160.7 47.0 59.5 128.4 53.1 66.4 106.0 93.7 61.2 120.5 94.5 74.1 87.6 53.7 139.5 169.5 101.0 133.3 86.3 102.7 133.0 105.7 150.6 59.6 103.7 56.0 55.6 71.4 112.8 78.9 93.0 134.1 171.7 148.0 43.4 76.3 75.9 227.3 79.2 118.3 70.8 93.0 214.7 119.1 64.1 89.0 81.0 225.0 169.9 239.4 62.4 80.2 126.1 62.7 76.2 109.5 47.0 78.4 88.1 73.6 55.6 47.1 109.3 49.2 120.4 68.3 2.0 2.5 4.3 4.1 4.3 3.4 7.4 3.5 3.8 3.1 2.1 4.5 4.9 0.2 3.0 5.5 6.8 4.4 1.4 24.7 25.8 26.5 27.0 25.3 28.2 19.8 22.0 21.0 21.2 27.4 21.8 18.7 19.2 29.1 33.6 15.9 18.6 27.1 19.9 33.0 27.5 20.4 22.1 24.4 11.5 19.0 23.9 27.1 31.6 18.1 15.7 17.6 35.4 43.5 45.9 49.3 20.4 22.8 29.7 51.1 24.7 57.2 24.8 23.4 44.4 12.0 49.5 16.8 17.2 15.0 15.2 51.2 24.9 22.4 15.1 19.7 20.3 21.5 20.2 12.4 30.0 28.1 19.3 12.3 50.3 30.4 28.1 13.5 23.0 28.9 26.3 17.2 15.7 29.5 19.8 0.0 22.2 25.0 131.8 67.1 36.1 12.8 16.6 15.4 34.3 27.6 20.5 KDM3A "JHMD2A, JMJD1, JMJD1A, KIAA0742, TSGA" ENSG00000115548 "Lysine demethylase 3A" Q9Y4C1 2 86440647-86492716 "Enzymes, Predicted intracellular proteins" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Activator, Chromatin regulator, Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055543, HPA065162" Enhanced Nucleoplasm NA NA "Cluster 34: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 25: RPMI-8226 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "HPA055543: AB_2682842, HPA065162: AB_2685424" "unprognostic (1.97e-2)" "unprognostic (3.03e-3)" "unprognostic (1.32e-2)" "unprognostic (4.04e-2)" "unprognostic (5.06e-2)" "unprognostic (5.24e-2)" "prognostic unfavorable (2.15e-6)" "unprognostic (2.01e-1)" "unprognostic (3.35e-3)" "unprognostic (9.50e-3)" "unprognostic (4.44e-2)" "unprognostic (5.64e-2)" "prognostic unfavorable (5.25e-4)" "unprognostic (2.17e-1)" "unprognostic (2.24e-1)" "unprognostic (1.24e-1)" "unprognostic (2.66e-2)" 21.2 12.9 17.9 13.1 19.0 70.3 19.9 17.5 18.9 18.0 18.6 25.0 18.9 20.7 18.2 20.8 18.4 15.9 21.7 15.3 18.1 15.4 12.9 16.7 17.9 18.1 17.4 21.5 16.1 14.6 12.8 22.1 17.8 16.6 15.9 54.7 19.8 19.7 21.5 38.6 20.1 15.0 16.6 18.4 14.9 50.9 18.7 27.4 20.0 21.4 19.6 20.8 20.2 20.1 34.7 13.5 31.5 8.3 15.9 16.1 29.4 16.5 16.2 15.1 18.5 17.3 14.3 20.1 30.4 13.8 31.1 21.5 23.7 16.6 29.2 27.1 19.7 32.4 12.6 24.8 11.9 26.1 19.9 17.8 24.5 13.6 24.9 51.9 19.0 18.5 21.1 31.9 16.1 8.9 36.2 36.4 28.3 20.6 20.4 24.5 42.6 44.0 13.6 19.2 24.4 25.9 21.7 15.5 30.2 27.5 9.0 16.8 21.2 30.6 12.6 31.8 19.1 33.3 33.9 29.6 38.8 26.6 38.2 16.9 3.0 5.8 6.7 3.3 7.1 4.2 7.5 6.6 4.6 3.6 7.9 7.0 13.4 5.0 2.2 4.2 8.3 3.9 17.9 19.0 17.5 18.9 15.3 18.1 18.1 17.4 17.8 16.6 18.7 20.1 26.0 35.3 17.0 56.8 19.7 30.5 23.2 19.5 43.3 24.0 18.9 14.6 30.3 7.2 24.8 5.5 52.1 5.2 29.2 24.2 0.0 12.1 82.0 36.6 15.6 23.4 15.6 21.0 28.7 9.8 8.5 19.1 23.0 35.5 38.6 11.9 15.4 7.6 10.4 55.5 27.4 13.7 26.4 10.9 18.2 29.7 17.4 17.5 21.4 28.1 8.6 36.0 21.6 26.2 23.5 11.3 8.0 17.3 21.4 16.0 23.0 5.6 44.1 34.4 6.6 21.3 20.4 38.7 14.1 35.5 40.1 11.6 27.4 15.2 10.7 13.6 KDM4D "FLJ10251, JMJD2D" ENSG00000186280 "Lysine demethylase 4D" Q6B0I6 11 94973709-94999519 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "testis: 33.3" "Group enriched" "Detected in many" 7 "Early spermatids: 115.7;Late spermatids: 43.7;Spermatocytes: 102.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 2.1" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA055854, HPA064037" Approved Approved Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 74: Testis - Spermatogenesis" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "HPA055854: AB_2682944, HPA064037: AB_2685180" "unprognostic (1.98e-1)" "unprognostic (5.71e-2)" "unprognostic (1.83e-1)" "unprognostic (9.65e-3)" "unprognostic (3.19e-1)" "unprognostic (5.12e-2)" "unprognostic (2.84e-2)" "unprognostic (3.16e-1)" "unprognostic (3.11e-1)" "unprognostic (1.36e-1)" "unprognostic (1.37e-2)" "unprognostic (5.62e-2)" "unprognostic (4.49e-2)" "unprognostic (8.14e-2)" "unprognostic (1.84e-1)" "unprognostic (2.45e-1)" "unprognostic (2.88e-1)" 0.5 0.6 0.5 0.3 0.5 0.0 0.8 0.5 0.6 0.5 0.4 0.2 0.1 0.5 0.8 0.3 1.0 0.4 1.0 0.5 0.5 0.5 0.3 0.4 0.7 0.5 0.5 0.9 0.3 0.9 0.5 0.4 0.4 0.5 0.3 2.1 0.6 0.6 0.6 0.7 0.3 0.5 0.6 0.6 0.3 33.3 0.5 0.6 0.7 0.7 0.6 0.4 0.3 0.6 0.5 0.8 3.3 2.4 0.7 0.8 1.5 1.1 1.2 3.0 2.6 0.9 1.0 1.2 3.5 0.9 2.9 1.0 2.1 2.3 2.3 1.4 2.2 1.1 0.4 1.3 0.6 0.5 0.3 1.5 1.2 3.0 2.7 0.4 1.1 4.4 1.2 0.5 1.2 1.0 1.9 1.2 1.4 0.8 4.0 2.6 1.4 0.9 0.7 0.3 1.9 2.3 1.3 1.1 0.9 1.7 1.2 0.4 0.9 2.0 1.2 3.2 1.7 0.7 2.5 0.2 0.7 0.6 2.3 0.0 0.1 0.0 0.1 0.0 0.0 0.4 0.2 0.3 0.0 0.0 0.2 0.0 0.0 0.0 2.1 0.4 0.6 0.1 0.5 0.5 0.5 0.6 0.5 0.5 0.5 0.5 0.4 0.6 0.5 0.6 0.8 0.0 0.0 2.6 0.2 0.0 0.2 0.8 0.6 7.0 0.8 0.9 1.1 1.5 0.4 0.0 2.1 0.9 1.6 0.0 3.9 0.8 115.7 1.3 1.4 1.1 0.0 0.4 1.8 0.6 0.9 0.9 0.5 0.4 0.0 2.6 2.2 1.3 0.7 3.3 2.6 0.1 0.0 0.6 0.3 43.7 2.1 0.8 0.0 4.7 0.7 3.9 1.0 3.5 4.3 0.2 0.1 1.2 0.5 0.2 0.0 1.3 1.0 3.3 0.0 0.8 0.7 102.5 11.4 0.7 0.0 0.3 0.3 2.5 0.3 0.2 KDM5A "JARID1A, RBBP2" ENSG00000073614 "Lysine demethylase 5A" P29375 12 280057-389320 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, Dioxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 45.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006201 Supported "Nuclear bodies,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 5: NTERA-2 - Transcription" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nuclear bodies" Cytosol "HPA006201: AB_1079160" "unprognostic (2.75e-1)" "unprognostic (1.68e-1)" "unprognostic (1.83e-1)" "unprognostic (1.12e-1)" "unprognostic (4.46e-2)" "unprognostic (1.60e-1)" "unprognostic (3.53e-3)" "unprognostic (1.81e-2)" "unprognostic (5.81e-2)" "unprognostic (3.19e-1)" "unprognostic (1.77e-3)" "unprognostic (6.11e-2)" "unprognostic (1.79e-2)" "unprognostic (1.10e-1)" "unprognostic (1.52e-1)" "unprognostic (2.60e-2)" "unprognostic (7.69e-2)" 8.1 8.7 5.8 11.4 8.3 45.5 11.1 11.6 8.5 8.6 10.0 8.2 7.2 9.7 7.1 8.9 7.6 8.0 5.2 6.2 6.5 7.8 9.9 8.8 15.3 6.8 5.7 11.0 9.4 10.1 4.2 11.8 6.5 8.6 9.9 9.6 6.7 7.3 5.5 12.5 7.3 9.4 6.0 13.5 8.8 21.1 6.7 21.6 9.1 7.6 14.4 8.7 7.2 15.0 14.4 25.3 18.3 14.2 16.1 15.2 20.3 12.5 16.5 18.4 19.8 15.2 17.0 24.0 3.9 21.0 16.0 13.3 19.2 14.2 21.9 37.9 15.9 29.3 26.5 9.0 13.0 38.6 22.1 16.6 13.1 22.6 29.9 18.8 18.8 21.0 17.9 32.7 15.7 9.7 27.9 11.0 28.4 12.3 7.9 25.7 47.5 11.4 8.8 32.6 7.0 20.5 24.5 11.0 13.0 25.0 11.9 24.0 26.0 12.0 17.0 13.6 21.1 11.5 13.6 53.7 15.5 16.5 18.0 64.5 21.8 44.4 31.4 25.0 32.3 27.1 24.6 25.9 22.8 32.0 26.3 22.8 63.0 35.8 28.9 32.0 20.9 22.5 5.8 8.3 11.6 8.5 6.2 6.5 6.8 5.7 6.5 6.0 6.7 15.0 53.1 64.1 61.6 61.7 80.6 33.0 22.2 30.1 48.9 69.0 35.3 27.9 38.2 31.5 39.0 35.0 116.7 48.8 103.3 51.3 3.9 37.4 96.8 60.2 72.8 51.6 69.7 51.3 71.7 31.6 34.7 47.2 39.8 99.8 54.4 106.9 42.8 30.9 30.2 87.5 59.1 40.0 40.7 52.5 37.5 32.5 48.4 63.9 26.6 57.1 82.9 48.3 105.0 68.3 85.9 38.7 37.0 55.7 73.1 32.4 33.6 11.8 40.2 71.9 59.2 64.0 59.9 137.1 104.8 50.1 47.6 71.1 80.1 67.5 40.1 42.0 KDM6A UTX ENSG00000147050 "Lysine demethylase 6A" O15550 X 44873188-45112779 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Chromatin regulator, Dioxygenase, Oxidoreductase" "Cancer-related genes, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglial cells: 116.2;Oligodendrocyte precursor cells: 118.1;Oligodendrocytes: 264.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000568, HPA001165, HPA002111" Enhanced Approved "Nucleoplasm,Nucleoli,Nucleoli rim" "Intracellular and membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 3: HMC-1 - Innate immune response" "Cluster 44: Endometrium - Transcription" "Nucleoli, Nucleoli rim" Nucleoplasm "HPA000568: AB_1858705, HPA001165: AB_1080541, HPA002111: AB_1858704" "unprognostic (1.73e-3)" "unprognostic (6.86e-3)" "unprognostic (1.45e-2)" "unprognostic (1.36e-1)" "unprognostic (1.72e-1)" "unprognostic (2.65e-2)" "unprognostic (2.58e-3)" "unprognostic (8.22e-3)" "unprognostic (3.23e-1)" "unprognostic (2.44e-1)" "unprognostic (2.56e-1)" "unprognostic (1.07e-1)" "unprognostic (2.73e-1)" "unprognostic (2.24e-2)" "unprognostic (5.18e-2)" "unprognostic (1.26e-1)" "unprognostic (3.16e-2)" 9.6 8.0 6.7 4.5 7.6 19.4 10.6 7.2 10.6 15.7 6.5 9.1 6.2 14.0 5.1 11.1 14.0 3.4 6.6 6.8 6.9 6.8 10.4 10.8 8.0 7.3 6.8 17.2 10.8 6.4 8.6 3.9 7.3 7.7 4.1 3.8 10.5 3.1 10.4 18.4 13.0 4.1 7.1 14.1 12.5 12.2 7.0 12.9 9.4 6.1 5.3 9.8 15.2 9.9 7.3 5.8 7.0 9.3 5.0 6.8 15.7 4.9 4.2 4.0 4.1 10.4 5.2 4.6 3.2 3.5 10.1 13.9 6.5 5.4 3.9 7.6 10.8 2.4 4.5 5.2 3.7 2.6 13.2 2.6 6.4 8.2 6.6 5.1 4.2 5.3 6.4 10.1 2.4 6.0 6.9 13.6 6.8 4.2 7.4 6.4 7.1 1.4 3.8 9.2 6.2 4.4 18.2 6.8 10.7 14.1 8.5 0.0 3.0 5.4 5.2 5.2 3.6 5.5 8.8 5.6 4.0 3.3 3.3 7.3 1.7 1.5 1.9 3.5 2.1 1.9 2.5 2.8 3.1 1.2 2.5 2.4 2.8 2.8 3.0 1.7 2.2 2.0 6.7 7.6 7.2 10.6 6.8 6.9 7.3 6.8 7.3 7.1 7.0 9.9 23.2 6.4 10.6 92.1 26.0 26.1 14.3 9.4 38.1 7.7 16.8 12.1 12.8 12.8 10.9 7.3 14.6 4.5 26.1 24.6 0.0 8.4 1.5 26.4 25.5 13.1 13.1 16.8 88.3 7.5 7.9 14.2 23.0 39.7 2.5 27.3 6.4 17.6 7.0 25.2 74.0 14.0 6.1 9.1 13.8 2.0 6.5 19.9 10.6 116.2 12.6 6.8 6.2 118.1 264.6 9.1 17.4 7.2 31.4 14.2 22.6 3.7 8.9 9.7 6.6 20.9 17.0 14.1 12.5 29.3 26.3 10.9 27.4 10.6 13.1 17.1 KHDC1L RP11-257K9.7 ENSG00000256980 "KH domain containing 1 like" Q5JSQ8 6 73223544-73225770 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 4 "brain: 1.7;pituitary gland: 1.5;testis: 5.5" "Group enriched" "Detected in some" 10 "Early spermatids: 31.8;Late spermatids: 96.9" "Cancer enriched" "Detected in some" 9 "testis cancer: 33.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "BEWO: 51.5" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 28: BEWO - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (1.18e-1)" "unprognostic (6.11e-5)" "unprognostic (3.06e-2)" "unprognostic (1.93e-1)" "unprognostic (3.07e-2)" "unprognostic (9.32e-2)" "unprognostic (2.52e-1)" "unprognostic (1.99e-2)" "unprognostic (1.48e-1)" "unprognostic (4.01e-2)" "unprognostic (1.31e-2)" "unprognostic (4.13e-1)" "unprognostic (6.63e-2)" "unprognostic (3.17e-3)" 0.0 0.0 1.1 0.0 1.7 0.2 0.0 1.3 1.7 0.1 0.7 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.8 0.9 0.0 0.0 0.6 0.0 0.8 0.9 0.2 0.1 0.1 1.5 0.5 0.8 0.2 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.1 5.5 0.8 0.4 0.1 0.0 0.4 0.1 0.1 1.0 10.7 0.2 0.0 0.4 0.0 0.0 51.5 0.2 0.3 0.3 0.2 0.4 0.2 0.4 0.4 0.0 0.0 0.1 0.2 0.1 0.1 0.2 0.0 0.1 0.1 0.0 0.1 0.3 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.3 0.2 0.2 0.5 0.0 0.1 0.1 0.0 3.4 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.8 0.0 0.3 0.0 0.2 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.7 1.3 1.7 0.8 0.9 0.8 0.9 0.8 0.8 0.8 1.0 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.2 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 31.8 0.1 0.0 0.0 0.0 0.0 0.3 0.4 1.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 96.9 0.3 0.2 0.0 0.0 0.6 0.1 0.0 1.0 0.2 0.3 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 2.3 5.9 0.0 0.0 0.1 0.0 0.2 0.1 0.1 KHDRBS3 "Etle, etoile, SALP, SLM-2, SLM2, T-STAR" ENSG00000131773 "KH RNA binding domain containing, signal transduction associated 3" O75525 8 135457456-135656722 "Predicted intracellular proteins" "Host-virus interaction, mRNA processing, Transcription, Transcription regulation" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 157.7" "Cell type enhanced" "Detected in many" "Early spermatids: 364.5;Excitatory neurons: 828.6;Inhibitory neurons: 190.8;Microglial cells: 227.7;Oligodendrocyte precursor cells: 578.6;Spermatocytes: 276.1" "Cancer enhanced" "Detected in all" "glioma: 9.0" "Group enriched" "Detected in many" 5 "amygdala: 21.4;basal ganglia: 27.9;cerebral cortex: 50.9;hippocampal formation: 29.8;white matter: 41.1" "Immune cell enriched" "Detected in single" 13 "eosinophil: 1.2" "Lineage enriched" "Detected in single" 13 "granulocytes: 1.2" "Cell line enhanced" "Detected in many" "REH: 87.8;RPTEC TERT1: 76.0;WM-115: 85.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000275, HPA000500, HPA000981" Enhanced Supported Nucleoplasm NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "HPA000275: AB_1079183, HPA000500: AB_1079184, HPA000981: AB_2666164" "unprognostic (1.36e-1)" "unprognostic (1.61e-1)" "unprognostic (1.98e-1)" "unprognostic (6.55e-3)" "unprognostic (2.75e-1)" "unprognostic (2.43e-1)" "unprognostic (1.31e-3)" "unprognostic (9.36e-2)" "unprognostic (2.00e-2)" "unprognostic (2.66e-1)" "unprognostic (1.91e-2)" "unprognostic (1.21e-1)" "prognostic favorable (7.16e-6)" "unprognostic (6.63e-2)" "unprognostic (7.85e-2)" "unprognostic (1.07e-1)" "unprognostic (1.33e-3)" 16.8 16.4 21.4 5.6 27.9 2.6 11.5 0.0 50.9 17.0 0.0 12.5 4.1 6.8 22.8 6.2 6.5 11.5 10.3 29.8 0.6 19.3 12.3 8.8 3.0 7.5 1.4 9.3 9.2 7.6 6.8 2.0 0.4 8.4 8.9 21.1 11.0 12.3 32.6 6.4 5.9 8.7 0.0 2.8 6.9 157.7 5.7 9.2 5.6 31.2 4.2 10.6 9.0 41.1 0.5 1.8 30.9 1.7 6.5 12.0 12.4 20.7 28.6 19.2 9.8 11.1 4.4 0.1 10.9 19.8 0.3 2.7 19.5 20.9 26.0 4.4 33.6 0.1 11.2 22.9 5.0 5.8 69.8 2.6 2.8 10.5 16.1 23.2 15.9 36.7 2.6 51.0 34.5 7.5 2.2 1.2 6.3 16.9 34.0 87.8 42.0 22.6 76.0 0.6 39.5 33.4 1.5 4.4 22.6 19.4 1.4 1.8 1.3 23.6 40.7 0.4 45.2 17.9 0.0 0.1 14.3 0.0 85.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.4 27.9 0.0 50.9 29.8 0.6 7.5 1.4 0.4 0.0 5.7 41.1 15.4 28.9 5.3 20.2 3.1 15.0 14.7 2.3 2.8 160.9 23.8 10.8 12.3 2.8 4.8 7.3 0.0 0.6 0.6 7.0 25.4 14.6 364.5 24.2 21.1 13.7 23.4 0.8 828.6 22.9 1.2 37.2 2.0 40.7 4.5 4.0 5.0 21.8 0.8 6.7 190.8 8.7 10.2 3.5 10.9 142.4 16.1 5.2 14.2 227.7 1.6 7.0 0.0 578.6 34.9 19.8 2.5 8.6 1.1 19.3 2.1 29.0 2.9 16.1 0.0 57.9 34.5 276.1 33.1 3.4 9.2 1.4 2.1 12.7 6.6 12.6 KIAA0100 "BCOX, BCOX1, CT101, DKFZp686M0843, FMP27, MGC111488" ENSG00000007202 KIAA0100 Q14667 17 28614446-28645454 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042781 Uncertain Approved "Nuclear speckles,Cytosol" "Secreted to blood" No No "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 8: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles, Cytosol" "HPA042781: AB_10797020" "unprognostic (1.91e-1)" "unprognostic (1.03e-2)" "unprognostic (3.47e-2)" "unprognostic (5.26e-3)" "unprognostic (2.43e-1)" "unprognostic (6.89e-2)" "prognostic unfavorable (3.47e-5)" "unprognostic (4.99e-2)" "unprognostic (3.04e-1)" "unprognostic (3.03e-3)" "unprognostic (2.40e-2)" "unprognostic (2.53e-1)" "unprognostic (4.24e-3)" "unprognostic (7.58e-2)" "unprognostic (5.84e-2)" "unprognostic (1.22e-1)" "unprognostic (6.67e-2)" 36.1 30.7 22.4 28.5 20.7 31.5 30.6 18.2 23.5 22.7 31.7 30.8 19.7 23.1 25.7 31.3 29.2 20.5 24.2 24.4 21.3 43.0 18.6 30.7 28.4 29.9 24.4 23.9 24.4 51.8 25.2 29.6 29.3 27.1 34.8 27.5 28.9 27.1 51.9 31.8 26.7 35.3 20.2 28.8 23.3 24.9 26.5 32.3 35.4 42.5 34.9 30.3 16.0 20.6 66.5 123.8 61.4 58.8 109.3 64.8 44.8 60.9 80.1 72.3 67.6 85.9 29.4 92.0 71.2 111.2 75.3 86.2 91.4 89.6 87.1 102.8 88.7 73.2 95.9 47.2 47.0 129.1 121.3 66.5 68.2 98.0 74.1 56.1 104.9 64.1 70.6 29.0 66.8 94.4 94.5 61.1 26.9 119.0 46.6 71.7 69.0 60.0 43.4 116.9 60.2 46.5 76.8 205.5 50.7 76.0 123.2 88.6 98.1 55.0 60.4 74.5 116.2 27.2 33.8 58.0 62.8 81.7 65.4 0.3 1.1 1.5 1.2 1.0 1.2 1.1 0.5 1.0 1.3 0.6 0.6 0.7 0.7 0.8 1.2 2.9 0.7 0.7 22.4 20.7 18.2 23.5 24.4 21.3 29.9 24.4 29.3 20.2 26.5 20.6 21.5 16.0 17.8 15.0 16.5 10.3 8.9 8.7 15.4 31.7 19.3 14.7 30.2 14.3 13.0 12.9 29.2 15.3 34.4 30.5 5.9 9.9 19.4 20.4 16.1 16.4 12.1 14.1 19.1 11.0 9.4 14.1 21.4 16.4 8.2 20.4 18.5 30.5 10.6 28.6 18.3 16.4 8.2 31.5 18.6 23.2 9.3 19.9 10.6 14.0 25.3 14.3 21.6 11.6 12.7 9.8 12.1 6.4 17.1 15.8 17.9 15.1 15.1 22.5 0.0 20.3 20.1 30.5 28.1 22.9 11.1 45.6 17.0 24.2 22.6 11.7 KIAA1210 ENSG00000250423 KIAA1210 Q9ULL0 X 119078635-119150579 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "epididymis: 39.4;seminal vesicle: 19.8;testis: 30.9" "Cell type enhanced" "Detected in some" "Early spermatids: 4.0;Endometrial stromal cells: 25.2;Granulosa cells: 11.1;Late spermatids: 11.5;Peritubular cells: 6.0" "Cancer enhanced" "Detected in single" "prostate cancer: 1.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "MCF7: 1.0" "Not detected" "Not detected" "HPA000551, HPA048322" Enhanced Approved "Golgi apparatus,Vesicles" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 36: Stromal cells - Cell proliferation" "Golgi apparatus, Vesicles" "HPA000551: AB_1079165, HPA048322: AB_2680358" "unprognostic (2.48e-1)" "unprognostic (5.63e-2)" "unprognostic (1.77e-1)" "unprognostic (1.43e-1)" "unprognostic (3.90e-1)" "unprognostic (2.25e-2)" "unprognostic (1.16e-2)" "unprognostic (6.29e-2)" "unprognostic (2.53e-1)" "unprognostic (1.06e-1)" "unprognostic (2.92e-2)" "unprognostic (5.69e-2)" "unprognostic (1.05e-1)" "unprognostic (8.45e-2)" "unprognostic (1.04e-1)" "unprognostic (1.24e-1)" "unprognostic (6.26e-4)" 0.0 1.4 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.0 0.0 0.0 1.6 39.4 0.0 5.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 4.7 0.0 0.0 0.0 19.8 0.3 0.0 0.0 0.2 0.0 0.0 0.0 30.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.2 0.4 1.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 4.0 1.9 25.2 0.2 0.0 0.0 0.1 0.0 0.2 0.3 0.0 1.6 0.0 11.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.3 11.5 3.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 6.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.5 2.4 1.1 0.0 0.0 0.3 0.1 0.3 0.0 0.0 KIAA1217 "DKFZP761L0424, ETL4, SKT" ENSG00000120549 KIAA1217 Q5T5P2 10 23694746-24547848 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 108.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 609.1;Inhibitory neurons: 1251.8;Oligodendrocyte precursor cells: 255.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 82.6;Karpas-707: 75.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004941 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 28: BEWO - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Cytosol" "HPA004941: AB_2130659" "unprognostic (3.60e-2)" "unprognostic (7.55e-3)" "unprognostic (1.20e-1)" "unprognostic (2.73e-2)" "unprognostic (1.27e-1)" "unprognostic (4.45e-3)" "unprognostic (1.60e-3)" "unprognostic (2.03e-3)" "unprognostic (1.87e-2)" "unprognostic (4.62e-2)" "prognostic unfavorable (7.63e-4)" "unprognostic (2.69e-1)" "unprognostic (1.84e-3)" "unprognostic (5.27e-2)" "unprognostic (2.44e-1)" "unprognostic (2.97e-1)" "unprognostic (1.22e-1)" 28.4 16.5 9.8 3.5 12.1 0.2 30.5 2.2 9.6 15.7 42.2 13.1 12.9 6.0 13.3 30.9 16.9 14.7 17.8 27.5 2.0 18.0 17.5 14.4 2.6 6.0 11.2 13.1 13.6 42.8 6.5 20.9 5.7 20.5 14.7 23.7 39.2 22.5 108.4 17.6 11.3 3.3 0.5 7.5 17.4 15.7 4.2 12.6 33.6 52.7 9.3 12.1 19.1 17.2 19.5 9.7 3.8 0.1 2.4 6.8 82.6 3.7 6.0 8.6 18.2 16.6 30.3 1.0 18.6 7.6 17.6 31.5 4.7 36.2 9.5 7.2 3.4 0.4 23.1 19.4 4.2 0.0 0.3 25.3 22.8 19.0 5.2 3.9 0.0 1.7 0.0 75.7 4.4 6.8 10.8 0.6 8.5 18.9 8.7 0.8 22.0 16.2 20.1 25.3 2.4 1.3 9.4 31.4 0.0 38.3 15.2 0.0 20.3 13.1 14.1 52.9 4.9 33.4 30.4 0.1 43.4 0.5 0.6 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 9.8 12.1 2.2 9.6 27.5 2.0 6.0 11.2 5.7 0.5 4.2 17.2 149.7 38.5 34.4 27.4 1.0 121.3 74.1 58.0 145.1 13.6 38.8 39.0 39.1 24.3 73.7 33.1 8.4 50.2 0.4 52.5 3.9 32.3 33.7 64.5 19.6 34.4 23.9 0.0 609.1 26.2 21.2 23.3 50.0 85.9 1.3 6.6 25.0 24.8 5.3 0.0 1251.8 22.8 26.4 14.6 7.8 11.3 17.7 1.3 1.8 30.0 0.0 93.6 0.0 255.9 10.3 24.1 22.7 33.1 3.1 36.8 15.4 6.3 36.9 3.1 13.1 19.6 20.4 0.8 1.1 96.4 51.0 65.1 2.2 14.2 19.4 43.7 KIAA1328 ENSG00000150477 KIAA1328 Q86T90 18 36829106-37232172 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 75.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 230.8;Alveolar cells type 2: 228.3;Inhibitory neurons: 113.9;Oligodendrocyte precursor cells: 117.6;Oligodendrocytes: 178.0;Respiratory ciliated cells: 122.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040946 Approved Approved "Nuclear speckles,Vesicles,Lipid droplets" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 16: U-266 - Nucleosome" "Cluster 11: Alveolar cells - Smell perception" "Nuclear speckles" "Vesicles, Lipid droplets" "HPA040946: AB_10794998" "unprognostic (3.66e-2)" "unprognostic (5.37e-4)" "unprognostic (2.76e-2)" "unprognostic (1.55e-3)" "unprognostic (1.59e-1)" "unprognostic (1.18e-2)" "unprognostic (2.46e-2)" "unprognostic (1.51e-3)" "unprognostic (1.99e-1)" "unprognostic (5.05e-2)" "unprognostic (3.18e-3)" "unprognostic (4.85e-2)" "unprognostic (1.06e-4)" "unprognostic (1.77e-1)" "unprognostic (2.25e-2)" "unprognostic (3.36e-2)" "unprognostic (2.64e-3)" 6.9 7.1 24.6 7.7 33.8 22.0 5.7 54.3 62.5 5.0 10.1 6.2 9.0 9.5 9.0 6.6 6.1 7.2 6.6 27.2 13.9 7.2 7.0 7.3 7.5 5.5 1.5 13.7 5.3 5.1 2.8 8.3 12.5 7.6 5.5 37.9 9.4 3.9 11.0 13.6 9.4 5.5 0.6 8.3 9.0 16.8 12.6 4.0 7.0 4.1 4.6 4.6 3.6 75.8 26.2 7.4 11.2 13.5 3.8 5.8 10.5 10.7 4.0 5.1 3.4 12.9 16.4 18.1 32.8 4.1 8.6 11.7 4.2 4.7 6.4 15.3 5.0 22.9 24.6 9.3 3.6 16.0 11.9 5.4 5.8 5.6 5.0 5.5 4.4 10.9 18.1 40.7 5.0 23.0 10.6 10.6 25.0 9.6 11.4 14.0 11.9 12.8 4.2 22.2 11.7 13.5 12.8 15.9 6.7 20.4 23.3 8.3 13.8 22.4 29.5 13.3 11.2 32.2 43.8 14.4 11.0 11.3 15.4 23.8 6.7 9.9 8.2 5.0 9.8 7.4 7.2 7.0 3.2 11.4 9.3 7.5 13.2 7.4 8.0 5.5 9.4 4.0 24.6 33.8 54.3 62.5 27.2 13.9 5.5 1.5 12.5 0.6 12.6 75.8 10.9 230.8 228.3 85.5 13.3 5.7 7.9 7.0 6.8 36.1 6.5 7.1 6.0 7.2 106.8 5.5 20.9 8.8 6.5 1.7 5.9 7.6 51.9 6.8 10.5 18.2 3.0 5.5 83.8 5.8 7.8 23.9 5.1 6.9 107.9 13.5 9.7 3.0 6.6 16.8 113.9 3.2 2.0 4.4 4.6 13.0 9.3 18.3 7.2 94.6 5.0 10.1 19.6 117.6 178.0 6.3 3.7 7.9 8.0 3.6 4.4 4.4 122.7 30.9 0.0 14.3 11.0 45.3 19.6 6.6 7.0 3.8 20.6 11.5 4.5 5.0 KIAA1586 ENSG00000168116 KIAA1586 Q9HCI6 6 57046532-57055239 "Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 87.0;Erythroid cells: 74.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA036370 Approved Approved "Nucleoplasm,Nuclear membrane" No No "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 1: K-562 - Erythropoiesis" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Nuclear membrane" "HPA036370: AB_10672219" "unprognostic (7.17e-2)" "unprognostic (3.05e-1)" "unprognostic (1.79e-1)" "unprognostic (1.29e-2)" "unprognostic (2.50e-2)" "unprognostic (1.03e-1)" "unprognostic (3.51e-2)" "unprognostic (1.08e-1)" "unprognostic (2.46e-2)" "unprognostic (4.96e-3)" "unprognostic (2.62e-2)" "unprognostic (1.55e-1)" "unprognostic (1.36e-3)" "unprognostic (5.64e-2)" "unprognostic (8.25e-2)" "unprognostic (1.54e-2)" "unprognostic (1.07e-1)" 4.1 4.8 2.0 3.6 2.4 8.6 5.4 9.4 3.7 4.6 0.0 2.9 2.1 6.1 3.7 3.3 2.8 4.6 3.5 2.3 3.0 3.6 4.9 2.7 4.6 2.9 2.4 7.6 2.8 5.2 3.7 9.4 2.8 5.2 2.6 4.0 2.7 3.6 1.6 2.5 2.4 4.4 1.4 4.5 2.1 8.0 2.8 5.9 5.7 3.4 3.9 4.8 2.6 2.6 8.6 3.5 21.9 25.1 8.5 13.7 12.0 14.1 11.6 12.0 14.4 5.9 2.7 3.4 11.4 10.4 10.6 4.2 16.7 8.3 16.4 10.7 12.7 35.9 8.0 13.3 11.1 29.0 12.7 10.1 5.9 10.6 11.7 8.5 11.5 9.1 49.9 2.7 14.4 6.8 14.0 17.5 14.2 3.0 5.0 12.8 16.0 8.4 8.0 17.6 18.5 16.8 9.3 3.0 10.6 15.1 7.2 26.0 9.4 18.6 7.7 17.9 10.2 10.9 15.4 16.8 11.5 21.0 7.7 0.2 2.5 2.0 2.3 2.0 2.7 3.7 3.4 3.0 3.9 3.1 4.2 3.6 0.1 5.3 2.0 4.0 4.4 1.9 2.0 2.4 9.4 3.7 2.3 3.0 2.9 2.4 2.8 1.4 2.8 2.6 15.4 9.6 6.3 10.4 8.8 10.5 4.5 13.0 13.1 15.4 7.4 11.7 23.1 1.5 7.8 7.3 2.1 43.3 11.7 1.0 11.7 7.0 87.0 4.6 29.6 12.5 5.4 74.9 32.4 5.4 33.2 21.4 3.1 3.2 13.3 30.5 8.2 4.0 12.5 10.1 32.7 2.4 6.1 6.6 7.1 21.9 12.8 8.9 3.6 12.2 9.7 9.6 15.5 23.6 24.4 2.8 0.9 14.7 13.0 2.3 0.7 14.6 8.4 8.2 19.7 19.5 17.6 23.4 17.9 8.7 4.4 10.7 10.6 29.5 3.2 1.6 KIAA1958 FLJ39294 ENSG00000165185 KIAA1958 Q8N8K9 9 112486827-112669397 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 14.5" "Cell type enhanced" "Detected in many" "Astrocytes: 169.8;Excitatory neurons: 64.2;Inhibitory neurons: 55.1;Oligodendrocyte precursor cells: 127.6;Oligodendrocytes: 166.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020625 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 29: U-266 - Adaptive immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane, Cytosol" "HPA020625: AB_1852451" "unprognostic (3.09e-3)" "unprognostic (1.04e-1)" "unprognostic (1.61e-2)" "unprognostic (1.33e-1)" "unprognostic (7.48e-2)" "unprognostic (2.08e-2)" "unprognostic (2.01e-1)" "unprognostic (4.95e-2)" "unprognostic (1.14e-1)" "unprognostic (1.65e-2)" "unprognostic (2.73e-2)" "unprognostic (7.67e-2)" "unprognostic (5.48e-3)" "unprognostic (3.14e-2)" "unprognostic (1.82e-1)" "unprognostic (2.10e-2)" "unprognostic (2.58e-1)" 1.1 6.6 5.5 1.1 10.5 4.9 2.2 9.3 6.9 5.1 4.4 1.4 1.7 3.4 0.9 1.5 3.0 1.3 1.3 3.9 6.6 5.8 3.4 2.1 1.3 8.2 8.9 9.9 2.6 1.4 1.8 0.7 7.0 1.5 1.5 10.0 3.0 2.4 0.9 1.6 1.9 3.1 7.5 1.5 4.8 5.8 10.7 3.9 2.4 0.8 1.3 1.4 1.9 14.5 3.7 5.2 20.7 6.0 1.4 0.3 9.9 2.7 0.9 3.2 3.6 9.5 2.4 11.8 3.1 8.9 2.2 3.2 15.3 1.5 4.5 3.6 6.2 4.6 7.3 6.7 0.8 7.0 5.6 0.6 1.2 4.2 2.0 2.9 2.6 11.0 11.0 2.9 1.0 4.2 11.0 4.0 11.4 8.6 2.4 8.8 11.8 3.3 4.3 5.1 10.6 11.2 4.5 4.7 2.7 11.4 4.3 7.1 0.5 1.1 6.1 0.7 3.3 5.3 10.4 6.9 1.4 4.8 0.8 0.4 0.7 0.0 0.5 0.2 0.2 0.0 0.1 0.3 0.2 0.4 0.4 0.6 0.6 0.6 0.2 0.6 0.1 0.4 5.5 10.5 9.3 6.9 3.9 6.6 8.2 8.9 7.0 7.5 10.7 14.5 0.5 3.2 19.3 169.8 3.7 4.7 3.4 1.5 6.8 20.6 7.9 4.2 4.3 4.3 6.2 1.8 14.6 1.2 3.0 4.6 7.9 3.2 4.1 12.1 8.1 1.4 4.8 3.8 64.2 6.7 1.0 3.3 8.2 8.0 0.0 20.3 0.4 8.0 1.0 6.7 55.1 4.4 12.2 7.5 4.6 2.5 6.5 4.2 1.8 15.9 2.5 8.3 3.1 127.6 166.4 3.3 6.2 5.3 5.0 6.5 5.0 11.0 5.9 12.1 6.6 2.5 4.1 1.5 8.0 5.3 4.7 0.8 1.6 29.9 5.2 5.7 KIF17 "KIAA1405, KIF17B, KIF3X, KLP-2, OSM-3" ENSG00000117245 "Kinesin family member 17" Q9P2E2 1 20664014-20718017 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 23.2" "Cell type enhanced" "Detected in many" "Adipocytes: 18.9;Early spermatids: 44.0;Hepatic stellate cells: 15.4;Late spermatids: 88.7;Sertoli cells: 19.7" "Cancer enhanced" "Detected in many" "testis cancer: 3.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 1.6;hTERT-HME1: 3.7;U-2 OS: 2.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA032085 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "Plasma membrane" "HPA032085: AB_10669917" "unprognostic (4.15e-3)" "unprognostic (8.60e-3)" "unprognostic (6.43e-2)" "unprognostic (1.12e-2)" "unprognostic (7.68e-2)" "unprognostic (3.70e-1)" "unprognostic (1.07e-2)" "unprognostic (1.04e-1)" "unprognostic (7.11e-2)" "unprognostic (1.08e-1)" "unprognostic (7.34e-3)" "unprognostic (8.73e-2)" "unprognostic (3.63e-3)" "unprognostic (1.08e-2)" "unprognostic (2.26e-1)" "unprognostic (1.22e-1)" "unprognostic (1.20e-2)" 0.0 0.2 2.3 0.0 2.2 0.0 0.0 0.0 3.3 0.3 1.8 0.2 0.1 0.4 0.0 0.0 1.8 0.0 0.0 2.3 4.9 0.4 0.1 0.2 0.0 0.6 1.4 0.2 0.0 0.0 0.6 0.0 0.4 0.2 0.0 0.2 0.0 0.3 0.0 0.0 0.1 0.5 0.3 0.0 0.0 23.2 3.1 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.8 0.7 0.4 0.0 0.0 0.0 0.1 1.2 1.6 0.6 0.4 0.2 0.4 0.0 0.5 0.9 0.3 0.0 0.6 0.4 0.4 0.0 0.1 0.0 0.0 0.2 0.7 0.0 0.0 0.1 0.3 0.5 3.7 0.4 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.0 1.1 0.0 0.8 0.0 0.0 0.0 0.3 0.0 0.3 0.6 0.2 0.0 0.1 0.7 0.0 0.0 0.0 0.2 2.3 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 2.2 0.0 3.3 2.3 4.9 0.6 1.4 0.4 0.3 3.1 0.0 18.9 0.0 0.0 0.7 0.2 1.7 0.0 0.1 0.6 0.0 0.2 0.3 2.8 0.0 0.2 1.8 4.2 0.1 2.8 0.1 0.0 0.0 44.0 2.8 0.3 15.2 0.0 0.0 11.0 0.0 0.1 0.9 0.0 0.2 0.0 0.0 15.4 0.5 5.1 0.0 2.8 0.0 0.0 1.6 9.8 88.7 1.2 3.2 1.8 1.9 0.2 0.0 0.0 0.0 0.7 0.0 0.0 3.8 0.1 0.1 0.1 0.3 3.5 0.3 19.7 0.5 2.7 3.2 4.3 0.1 1.3 1.6 0.2 5.2 0.1 0.2 KIF20A RAB6KIFL ENSG00000112984 "Kinesin family member 20A" O95235 5 138178719-138187723 "Predicted intracellular proteins" "Protein transport, Transport" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 14.1;lymphoid tissue: 24.6;testis: 11.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 11.0;Erythroid cells: 24.6;Extravillous trophoblasts: 13.1;Granulosa cells: 11.1;Spermatocytes: 21.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "NK-cell: 6.6;T-reg: 2.5" "Group enriched" "Detected in many" 46 "NK-cells: 6.6;T-cells: 2.5" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA036909, HPA036910" Approved Uncertain "Nucleoplasm,Cytokinetic bridge" Yes Yes "Cluster 15: NK-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cytokinetic bridge" "HPA036909: AB_10670245, HPA036910: AB_10671716" "unprognostic (7.50e-2)" "unprognostic (2.43e-1)" "unprognostic (1.39e-3)" "unprognostic (1.21e-2)" "unprognostic (3.47e-2)" "unprognostic (2.60e-2)" "prognostic unfavorable (2.14e-12)" "prognostic unfavorable (6.79e-4)" "unprognostic (2.86e-2)" "unprognostic (3.16e-1)" "prognostic unfavorable (1.90e-4)" "unprognostic (9.73e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (9.05e-2)" "unprognostic (2.61e-1)" "unprognostic (1.09e-1)" "unprognostic (3.16e-1)" 0.7 0.8 0.0 4.5 0.1 14.1 1.3 0.1 0.1 1.0 0.1 3.3 3.5 1.4 0.0 6.6 0.4 0.8 0.5 0.0 0.1 0.4 0.9 0.9 8.6 0.1 0.2 0.2 0.2 0.1 0.0 5.4 0.1 0.2 5.1 0.0 1.0 0.1 0.1 4.4 2.8 5.8 0.0 1.9 2.1 11.7 0.5 24.6 0.5 0.1 13.1 1.6 2.0 0.1 87.8 59.5 127.8 84.4 6.7 12.3 53.9 75.0 68.9 162.3 121.4 111.9 80.5 38.8 39.2 96.5 60.6 85.9 121.7 142.5 160.9 56.4 57.4 57.2 101.1 70.7 0.3 28.2 25.1 4.8 2.3 86.2 49.5 27.1 106.7 53.9 24.4 70.4 113.9 81.5 47.6 26.7 80.6 51.8 63.7 51.2 128.5 39.5 43.9 42.3 37.8 37.5 144.1 47.9 30.9 161.6 60.8 28.5 51.1 41.6 60.5 38.0 126.4 36.0 37.5 42.0 26.7 81.1 82.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 2.5 0.3 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.1 0.0 0.5 0.1 0.3 0.0 1.7 0.0 0.8 0.4 0.4 2.9 0.0 0.0 1.1 1.3 0.3 0.0 0.7 0.0 0.0 11.0 0.1 2.8 0.0 0.1 1.0 1.0 1.9 1.7 0.0 24.6 0.0 0.0 13.1 3.1 2.6 1.3 4.5 11.1 3.3 0.4 6.1 0.0 0.0 1.6 6.1 2.2 0.4 2.0 0.3 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.4 3.0 0.3 1.2 0.0 0.9 0.0 0.0 0.5 4.4 21.7 7.5 5.3 0.4 1.0 0.7 0.8 3.4 0.6 KIF21B "DKFZP434J212, KIAA0449" ENSG00000116852 "Kinesin family member 21B" O75037 1 200969390-201023714 "Plasma proteins, Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 34.1;brain: 21.6;retina: 21.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 25.7;Cone photoreceptor cells: 58.4;Late spermatids: 82.1;Rod photoreceptor cells: 26.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 5 "basophil: 6.0" "Lineage enriched" "Detected in many" 5 "granulocytes: 6.0" "Cell line enhanced" "Detected in many" "Daudi: 39.1;HMC-1: 41.0;JURKAT: 78.8;Karpas-707: 49.6;RPMI-8226: 43.8;U-266/70: 90.2;U-266/84: 44.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027249, HPA027274" Approved Approved "Plasma membrane,Mitotic spindle,Cytosol" Yes No "Cluster 11: Basophils - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "Mitotic spindle, Cytosol" "HPA027249: AB_10602241, HPA027274: AB_1852483" "unprognostic (3.49e-2)" "unprognostic (1.82e-1)" "unprognostic (4.70e-2)" "unprognostic (2.15e-1)" "unprognostic (2.28e-1)" "unprognostic (3.92e-3)" "unprognostic (1.32e-2)" "unprognostic (1.80e-1)" "unprognostic (2.18e-1)" "unprognostic (3.03e-1)" "unprognostic (1.54e-3)" "unprognostic (7.14e-2)" "unprognostic (1.41e-4)" "unprognostic (5.98e-3)" "unprognostic (2.64e-1)" "unprognostic (6.81e-2)" "unprognostic (5.81e-4)" 1.6 0.8 16.1 9.4 16.4 34.1 1.3 0.0 16.5 0.9 0.0 2.4 2.0 0.7 0.4 0.8 1.2 2.1 0.7 21.6 8.3 0.9 1.5 4.8 12.9 5.9 5.7 0.7 0.8 6.0 0.6 0.9 6.5 0.8 1.8 21.4 1.4 0.7 0.3 0.7 6.7 0.8 1.5 12.3 2.5 13.7 9.5 11.8 1.0 0.4 8.0 2.3 0.8 7.9 1.3 1.5 11.8 0.5 0.0 0.0 3.0 0.1 0.0 0.3 0.1 0.7 0.4 39.1 0.5 0.0 3.4 0.3 1.2 0.3 0.4 1.9 0.4 9.7 0.2 0.2 1.0 29.4 41.0 1.0 4.1 0.4 0.7 0.0 1.5 78.8 4.6 49.6 0.0 0.2 24.5 11.2 5.2 3.9 0.0 8.4 0.1 43.8 0.2 0.0 7.2 1.0 0.6 0.5 0.6 2.1 0.2 8.9 2.8 0.0 3.3 0.0 0.2 90.2 44.7 19.3 3.9 12.8 0.3 6.0 0.0 0.6 0.8 0.2 0.9 0.4 0.6 0.8 0.1 0.3 0.5 0.6 1.0 1.3 0.3 0.1 0.6 0.4 16.1 16.4 0.0 16.5 21.6 8.3 5.9 5.7 6.5 1.5 9.5 7.9 1.5 0.0 3.8 22.5 11.0 1.0 0.5 0.2 0.0 25.7 0.4 0.8 1.5 0.0 0.1 1.8 58.4 0.0 17.4 1.2 0.0 0.5 20.4 0.1 0.2 1.8 0.0 4.8 15.6 1.6 0.1 0.6 1.1 0.4 6.3 0.5 1.4 0.3 1.7 1.7 11.8 1.4 0.0 4.4 3.1 82.1 0.9 5.3 0.0 8.4 2.7 20.0 13.4 14.6 4.0 2.4 0.3 0.0 12.0 0.4 0.2 0.0 0.1 26.1 6.6 0.6 1.1 1.9 3.7 0.1 1.0 0.0 18.0 0.1 1.1 2.0 KIF2A "HK2, KIF2" ENSG00000068796 "Kinesin family member 2A" O00139 5 62306162-62391025 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Mitosis, Neurogenesis" "Developmental protein, Motor protein" "Cancer-related genes, Disease variant, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004715, HPA004716" Approved Enhanced Nucleoplasm,Nucleoli,Centrosome Yes No 300000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 51: Myeloid cells - Hemostasis" "Nucleoplasm, Nucleoli, Centrosome" "HPA004715: AB_2667215, HPA004716: AB_1079211" "unprognostic (2.40e-2)" "unprognostic (3.43e-1)" "prognostic favorable (1.70e-4)" "unprognostic (2.74e-2)" "unprognostic (1.43e-1)" "prognostic favorable (5.45e-4)" "prognostic unfavorable (3.17e-6)" "unprognostic (8.77e-3)" "unprognostic (4.69e-2)" "unprognostic (9.10e-2)" "unprognostic (1.85e-1)" "unprognostic (1.34e-1)" "prognostic unfavorable (3.81e-5)" "unprognostic (3.53e-2)" "unprognostic (2.95e-2)" "unprognostic (1.65e-1)" "unprognostic (1.58e-1)" 11.9 7.7 15.6 23.2 20.7 12.8 10.8 15.5 17.7 19.5 0.0 13.8 11.5 12.0 6.3 12.5 17.6 12.9 6.2 17.4 23.0 8.0 5.3 9.8 32.8 17.9 17.5 12.9 10.2 12.3 8.5 16.9 18.4 9.9 14.7 42.7 6.9 11.4 4.8 5.9 15.9 13.1 14.6 18.4 9.6 49.1 16.1 43.6 12.6 6.8 28.9 20.2 7.2 28.0 47.3 46.9 81.4 67.3 28.8 39.6 65.2 51.2 38.5 54.6 67.5 53.1 49.6 111.9 53.3 41.9 67.2 29.1 61.3 37.7 72.5 116.8 44.2 113.8 41.2 27.8 34.7 65.3 42.9 30.5 26.6 50.1 47.5 33.1 49.1 66.5 86.6 66.7 46.9 36.1 104.4 33.1 42.6 12.0 31.9 78.3 59.6 65.3 25.4 55.4 68.0 55.9 67.0 27.9 34.7 55.3 37.6 38.5 39.8 31.9 52.2 40.5 51.3 64.8 94.9 114.1 36.4 74.5 39.8 10.4 4.6 4.7 29.2 5.0 35.3 13.5 29.8 32.7 6.2 10.5 26.3 29.0 7.8 23.2 3.3 9.6 42.3 17.7 15.6 20.7 15.5 17.7 17.4 23.0 17.9 17.5 18.4 14.6 16.1 28.0 30.8 16.0 14.1 54.5 44.1 16.8 41.4 20.1 39.3 45.5 17.9 23.9 9.4 4.3 20.5 20.2 104.3 20.3 73.4 23.1 13.7 37.5 113.8 103.3 47.2 21.4 21.0 42.3 56.7 30.9 22.6 28.2 20.4 43.4 17.7 25.6 19.6 4.4 15.4 52.2 64.5 7.9 14.2 12.9 22.1 130.7 13.1 83.6 12.4 26.2 104.9 28.0 76.2 119.6 156.0 26.6 26.1 13.2 47.8 42.7 13.5 18.7 49.2 92.9 26.3 33.1 25.4 118.9 42.8 34.3 9.5 43.9 77.9 48.9 11.0 56.1 KIF4B ENSG00000226650 "Kinesin family member 4B" Q2VIQ3 5 155013755-155018141 "Plasma proteins, Predicted intracellular proteins" "DNA-binding, Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 19 "testis: 3.5" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 2.1;Early spermatids: 5.4;Late spermatids: 4.3;Spermatocytes: 9.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA034745, HPA034746, HPA061583" Uncertain Uncertain Nucleoplasm,Midbody Yes NA "Cluster 78: Testis - Spermatogenesis" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Midbody" "HPA034745: AB_10670978, HPA034746: AB_10670173, HPA061583: AB_2684564" "unprognostic (9.87e-3)" "unprognostic (1.17e-1)" "unprognostic (3.91e-3)" "unprognostic (1.71e-1)" "unprognostic (9.14e-2)" "unprognostic (1.71e-1)" "unprognostic (4.76e-2)" "unprognostic (1.94e-1)" "unprognostic (1.06e-1)" "unprognostic (4.37e-2)" "unprognostic (6.48e-9)" "unprognostic (7.24e-2)" "unprognostic (5.10e-2)" "unprognostic (1.71e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 2.1 0.1 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 4.3 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 9.2 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 KIF6 "C6orf102, dJ1043E3.1, dJ137F1.4, dJ188D3.1, DKFZp451I2418, MGC33317" ENSG00000164627 "Kinesin family member 6" Q6ZMV9 6 39329990-39725408 "Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 18.3;testis: 5.3" "Cell type enriched" "Detected in many" 5 "Oligodendrocytes: 220.3" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 22.1;RPMI-8226: 9.2;SCLC-21H: 12.2;SK-MEL-30: 5.0" "Low region specificity" "Detected in many" "Region enhanced" "Detected in single" "midbrain: 1.7" "HPA038811, HPA058624" Enhanced Approved Centrosome NA NA "Cluster 11: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Centrosome "HPA038811: AB_10795140, HPA058624: AB_2683781" "unprognostic (4.94e-2)" "unprognostic (3.38e-2)" "unprognostic (3.68e-1)" "unprognostic (1.02e-2)" "unprognostic (1.55e-1)" "unprognostic (8.25e-4)" "unprognostic (3.12e-3)" "unprognostic (1.00e-1)" "unprognostic (3.06e-1)" "unprognostic (3.48e-2)" "unprognostic (9.12e-4)" "unprognostic (1.08e-1)" "unprognostic (3.07e-2)" "unprognostic (3.10e-2)" "unprognostic (5.09e-2)" "unprognostic (3.92e-2)" "unprognostic (1.99e-1)" 0.3 0.3 8.0 0.1 15.5 0.1 0.5 10.5 9.3 0.3 1.5 0.2 0.5 0.2 0.5 0.3 3.8 0.4 0.3 7.2 8.6 0.3 0.3 0.8 0.3 12.3 9.8 0.2 0.4 0.3 1.2 0.3 11.1 0.2 0.1 3.0 0.1 0.1 0.4 0.2 0.2 0.1 8.0 0.2 0.2 5.3 10.0 0.1 0.6 0.2 0.1 0.0 0.0 18.3 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.1 1.0 0.3 0.5 0.1 0.0 0.0 0.1 1.0 22.1 0.2 0.1 0.0 0.2 0.0 0.3 0.1 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.3 0.0 0.6 0.0 0.2 0.0 0.0 0.1 0.1 0.1 0.6 0.0 0.0 0.5 9.2 0.2 0.0 12.2 0.1 0.0 0.1 5.0 0.3 0.1 0.1 0.1 0.0 0.1 2.9 0.7 0.2 0.0 0.0 0.7 0.0 1.5 0.5 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.1 0.1 0.5 0.2 0.1 0.6 0.0 0.0 8.0 15.5 10.5 9.3 7.2 8.6 12.3 9.8 11.1 8.0 10.0 18.3 0.2 0.0 0.6 31.3 0.1 0.1 0.7 1.0 0.0 3.9 0.5 0.5 1.3 0.0 2.2 0.0 10.4 0.3 0.0 0.0 1.9 1.5 9.1 23.9 1.0 0.8 2.4 0.0 8.6 0.9 0.5 2.7 0.0 1.0 0.0 0.4 0.0 0.0 0.3 3.3 15.6 0.0 0.0 0.0 1.5 10.3 0.3 0.3 0.0 1.9 0.1 12.9 0.0 5.0 220.3 0.1 0.1 0.0 0.1 0.3 0.0 3.5 40.0 16.3 0.0 3.1 0.8 17.0 3.1 0.1 0.4 0.3 0.2 2.2 0.0 0.4 KIFC3 ENSG00000140859 "Kinesin family member C3" Q9BVG8 16 57758217-57863053 "Cancer-related genes, Predicted intracellular proteins" "Motor protein" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 169.2" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 141.8;Early spermatids: 203.7;Late spermatids: 430.5;Rod photoreceptor cells: 165.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "A549: 215.1;HMC-1: 204.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021240 Uncertain NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 3: HMC-1 - Innate immune response" "Cluster 31: Spermatids - Spermatogenesis" "HPA021240: AB_1852509" "unprognostic (1.53e-1)" "unprognostic (3.10e-3)" "unprognostic (8.56e-3)" "unprognostic (1.11e-1)" "unprognostic (2.95e-3)" "unprognostic (2.29e-1)" "unprognostic (3.71e-2)" "unprognostic (1.10e-1)" "unprognostic (2.18e-1)" "unprognostic (7.66e-3)" "unprognostic (1.59e-2)" "unprognostic (2.18e-2)" "unprognostic (3.42e-2)" "unprognostic (2.14e-1)" "unprognostic (1.01e-2)" "unprognostic (1.40e-1)" "unprognostic (4.33e-2)" 30.5 29.0 25.4 25.9 16.6 14.5 23.8 28.2 35.9 22.7 13.4 21.0 30.7 22.2 30.1 26.2 14.8 21.1 62.7 21.2 38.5 169.2 85.6 45.4 13.5 25.7 14.2 19.0 76.6 26.1 30.9 25.6 29.9 26.3 13.4 82.3 22.1 22.3 13.7 80.0 37.4 13.0 7.3 21.2 24.5 64.9 35.0 4.1 68.1 6.6 9.6 30.3 24.4 46.4 41.5 215.1 15.2 32.8 4.9 10.4 26.8 51.1 65.1 76.4 36.3 58.2 62.6 4.4 64.5 32.8 79.3 43.2 1.8 47.1 25.6 2.1 10.2 34.6 72.9 75.8 28.8 5.0 204.7 14.2 16.6 40.3 40.5 39.1 18.4 11.9 61.7 7.4 28.6 28.2 7.4 60.9 10.3 16.2 45.6 4.6 23.1 33.0 48.9 21.3 5.3 10.7 86.8 60.7 55.8 10.5 18.2 26.0 39.9 98.4 69.3 45.3 71.5 5.9 3.7 4.3 49.9 3.3 94.7 0.1 0.2 0.2 1.5 0.0 0.1 0.7 0.6 1.5 0.1 0.5 0.3 0.4 0.5 0.1 0.7 0.1 0.0 0.6 25.4 16.6 28.2 35.9 21.2 38.5 25.7 14.2 29.9 7.3 35.0 46.4 40.0 48.1 33.3 28.4 0.5 12.6 12.3 8.1 5.7 5.7 5.0 7.4 8.4 38.6 15.3 66.2 141.8 31.8 9.2 0.1 50.9 50.6 203.7 18.5 4.8 25.3 0.0 4.8 15.8 63.6 6.4 11.8 2.0 15.6 3.8 0.9 25.4 16.6 25.7 1.7 14.8 2.1 2.0 6.6 10.2 430.5 12.2 24.7 28.4 16.9 1.1 10.6 15.5 27.2 28.9 67.1 1.2 22.6 0.8 13.8 34.7 51.4 14.9 165.5 19.7 10.3 16.5 7.7 9.9 1.0 8.2 19.4 5.8 10.5 0.9 7.9 KIT "C-Kit, CD117, PBT, SCFR" ENSG00000157404 "KIT proto-oncogene, receptor tyrosine kinase" P10721 4 54657918-54740715 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 114.9" "Cell type enhanced" "Detected in many" "Breast glandular cells: 83.1;granulocytes: 529.3;Inhibitory neurons: 111.2;Ionocytes: 101.7;Melanocytes: 211.7" "Cancer enhanced" "Detected in many" "testis cancer: 28.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "basophil: 20.3;eosinophil: 12.8;NK-cell: 13.1" "Group enriched" "Detected in many" 7 "granulocytes: 20.3;NK-cells: 13.1" "Group enriched" "Detected in many" 13 "HEL: 247.2;HMC-1: 496.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003288, HPA004471, CAB068253, CAB072867, HPA073252" Enhanced Supported Supported "Plasma membrane" NA NA 49000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 5: Breast - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "Plasma membrane" "CAB003288: AB_2335702, CAB068253: AB_2665717, CAB072867: AB_2665718, HPA004471: AB_1078431, HPA073252: AB_2686589" "unprognostic (1.55e-2)" "unprognostic (1.91e-1)" "unprognostic (4.04e-2)" "unprognostic (8.19e-2)" "unprognostic (3.96e-2)" "unprognostic (2.18e-2)" "unprognostic (2.33e-2)" "unprognostic (1.97e-2)" "unprognostic (3.60e-2)" "unprognostic (1.64e-1)" "unprognostic (2.20e-1)" "unprognostic (1.92e-2)" "prognostic favorable (5.63e-4)" "unprognostic (1.34e-3)" "unprognostic (1.87e-1)" "unprognostic (1.29e-2)" "unprognostic (2.30e-1)" 6.6 1.8 8.2 5.3 6.3 6.4 114.9 21.4 6.5 17.6 5.1 13.5 9.2 9.6 5.9 13.0 2.9 20.3 3.4 23.9 5.1 12.4 0.8 21.8 3.4 6.8 12.3 45.0 2.6 1.7 1.9 10.0 8.8 5.6 16.0 3.2 21.4 8.7 1.1 24.5 13.4 10.1 5.9 5.0 17.4 6.2 16.7 3.1 47.1 6.9 6.2 14.5 4.9 5.1 0.0 0.0 3.9 0.0 0.7 0.3 0.0 3.3 4.6 12.6 15.8 0.0 0.0 0.0 0.0 7.3 0.6 0.3 2.6 0.0 10.8 0.0 5.9 247.2 0.0 0.0 0.0 0.0 496.2 0.0 0.0 0.0 0.0 0.0 28.4 4.3 3.5 0.5 0.0 0.0 1.4 2.5 6.9 0.0 0.0 0.8 0.0 0.0 0.0 24.2 6.0 2.1 0.0 0.0 0.0 14.1 0.0 2.6 0.3 0.5 0.0 4.9 0.1 0.4 0.0 0.0 0.5 0.9 0.6 20.3 0.0 12.8 0.1 0.0 2.3 0.0 0.4 0.9 2.3 0.0 0.0 0.0 1.0 13.1 1.4 0.1 0.0 0.2 8.2 6.3 21.4 6.5 23.9 5.1 6.8 12.3 8.8 5.9 16.7 5.1 7.3 6.4 21.9 9.8 1.0 14.3 0.9 0.4 2.2 4.5 83.1 59.2 0.7 4.3 3.6 3.7 0.0 0.1 5.2 0.4 3.9 1.0 0.0 0.2 0.7 9.2 5.4 15.5 0.9 0.0 0.1 2.8 8.6 0.7 529.3 0.5 1.8 0.0 0.3 0.0 111.2 0.5 101.7 0.3 4.2 0.4 1.2 1.6 211.7 14.0 0.2 2.4 0.0 16.1 3.7 0.0 0.1 0.0 3.2 0.5 0.0 0.8 0.1 0.2 0.0 0.7 0.8 0.1 12.3 2.2 3.8 0.3 8.8 63.7 0.6 0.3 KIZ "C20orf19, HT013, NCRNA00153, PLK1S1" ENSG00000088970 "Kizuna centrosomal protein" Q2M2Z5 20 21125983-21246622 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 203.0;Late spermatids: 127.3;Oligodendrocyte precursor cells: 198.5;Oligodendrocytes: 166.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 92.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 43: Testis - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 34: Spermatids - Unknown function" "unprognostic (1.78e-1)" "unprognostic (1.77e-2)" "unprognostic (1.56e-1)" "prognostic favorable (4.45e-4)" "unprognostic (2.05e-2)" "unprognostic (5.71e-2)" "unprognostic (1.90e-1)" "unprognostic (9.71e-3)" "unprognostic (3.68e-2)" "unprognostic (1.44e-2)" "unprognostic (1.43e-3)" "unprognostic (1.64e-1)" "prognostic unfavorable (4.11e-8)" "unprognostic (4.82e-2)" "unprognostic (2.20e-1)" "unprognostic (4.94e-2)" "unprognostic (2.12e-1)" 17.6 9.8 22.7 7.2 30.2 10.7 15.4 27.7 29.2 32.5 20.2 72.2 15.1 27.0 11.2 8.0 19.8 12.6 17.5 21.8 25.1 14.4 11.3 9.8 10.6 30.7 27.9 35.5 24.3 14.6 23.3 8.9 31.6 19.3 13.2 20.2 13.6 23.8 29.4 14.9 17.8 17.1 25.2 13.6 16.3 45.4 28.2 16.6 26.9 14.6 11.1 36.5 22.9 36.9 7.5 5.9 7.9 7.5 27.3 37.3 10.9 10.6 17.9 8.8 10.4 6.4 6.1 14.0 8.9 12.5 9.3 6.2 8.0 22.4 12.2 7.9 9.2 11.3 11.2 92.8 13.8 13.9 9.2 28.2 45.8 8.6 28.2 20.8 8.3 23.3 18.6 18.8 7.6 6.4 14.7 18.0 10.8 13.5 5.9 9.2 22.5 13.7 9.7 13.0 10.7 20.9 21.4 11.4 22.4 17.9 7.3 27.1 7.8 9.2 8.0 7.2 7.7 18.9 13.7 10.5 4.5 15.5 8.4 4.6 5.0 12.5 10.4 5.6 12.2 11.7 10.9 10.5 3.1 11.4 11.5 12.6 16.5 8.4 4.2 7.3 14.3 5.0 22.7 30.2 27.7 29.2 21.8 25.1 30.7 27.9 31.6 25.2 28.2 36.9 11.0 0.0 10.0 41.1 22.6 0.0 9.2 0.0 9.6 35.4 7.6 10.7 16.6 12.8 5.0 18.4 37.5 7.8 16.6 4.4 7.9 5.0 203.0 24.6 16.0 8.7 11.4 11.6 76.4 7.1 7.6 19.4 6.1 9.8 8.8 18.9 7.5 5.2 4.0 50.5 99.0 9.1 0.0 6.0 0.0 127.3 38.8 6.1 0.0 27.2 7.6 28.1 16.5 198.5 166.8 3.5 5.6 31.6 25.9 4.0 21.7 5.9 10.2 35.1 13.1 20.8 11.4 78.3 37.4 7.7 0.0 4.2 17.8 12.9 9.7 10.9 KLB ENSG00000134962 "Klotho beta" Q86Z14 4 39406930-39451533 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "adipose tissue: 19.6;liver: 17.7;pancreas: 6.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 19.6;Enteroendocrine cells: 17.4;Hepatocytes: 51.4;Intestinal goblet cells: 12.1;Spermatocytes: 39.5" "Cancer enriched" "Detected in some" 16 "liver cancer: 11.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 24 "ASC diff: 6.7;Hep G2: 25.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA021136 Uncertain NA NA 320000 "Cluster 10: Basophils - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA021136: AB_1852616" "unprognostic (1.03e-2)" "unprognostic (1.61e-2)" "unprognostic (4.67e-2)" "unprognostic (2.69e-1)" "unprognostic (4.30e-2)" "unprognostic (7.02e-3)" "unprognostic (2.46e-1)" "unprognostic (9.92e-2)" "unprognostic (6.99e-3)" "unprognostic (4.51e-3)" "unprognostic (3.02e-3)" "unprognostic (8.90e-3)" "unprognostic (1.73e-1)" "unprognostic (5.03e-2)" "unprognostic (4.53e-2)" "unprognostic (3.87e-2)" "unprognostic (3.09e-2)" 19.6 0.1 0.2 0.2 0.4 0.3 3.5 0.9 0.6 0.0 0.0 0.6 0.2 0.0 0.0 0.3 0.2 0.1 0.1 0.2 0.2 0.2 17.7 1.6 0.0 0.3 0.0 0.0 6.0 0.1 0.0 0.0 0.2 0.1 0.5 0.0 0.4 0.0 0.0 0.6 0.6 0.0 0.0 0.0 1.3 2.8 0.1 0.0 0.0 0.2 0.1 0.1 0.1 0.3 0.0 0.3 0.1 0.0 6.7 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.1 25.7 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.4 0.1 0.3 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.6 0.0 0.0 0.2 0.4 0.9 0.6 0.2 0.2 0.3 0.0 0.2 0.0 0.1 0.3 0.6 3.2 19.6 0.0 0.7 0.5 1.1 1.4 0.0 1.6 0.7 1.1 1.2 0.0 1.2 0.0 0.0 0.4 0.5 1.6 0.0 1.1 8.5 4.4 1.5 0.4 17.4 0.0 0.5 4.3 1.5 0.5 2.6 2.2 0.0 0.2 0.4 51.4 0.2 1.7 0.6 12.1 2.0 1.0 0.6 3.2 1.5 0.4 1.8 0.0 0.1 0.4 0.0 0.5 0.2 0.9 4.8 0.7 0.0 1.2 2.1 1.1 0.4 2.3 0.0 1.2 0.5 39.5 0.9 2.0 0.9 1.4 0.8 0.5 1.1 1.1 KLHDC10 "KIAA0265, slim" ENSG00000128607 "Kelch domain containing 10" Q6PID8 7 130070534-130135705 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020119 Approved Approved Nucleoplasm NA NA "Cluster 24: B-cells - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "HPA020119: AB_2249467" "unprognostic (2.83e-1)" "unprognostic (6.26e-2)" "unprognostic (1.13e-1)" "unprognostic (8.16e-3)" "unprognostic (3.22e-1)" "unprognostic (1.80e-2)" "unprognostic (5.55e-2)" "unprognostic (8.70e-2)" "unprognostic (7.97e-2)" "unprognostic (1.42e-2)" "unprognostic (8.69e-2)" "unprognostic (2.43e-1)" "unprognostic (1.24e-2)" "unprognostic (8.22e-2)" "unprognostic (2.04e-1)" "unprognostic (2.23e-1)" "unprognostic (1.64e-2)" 12.3 17.3 19.4 9.5 19.8 7.9 14.6 27.0 17.2 12.4 21.6 12.8 11.1 13.0 13.7 12.6 14.9 9.5 13.5 18.5 26.3 21.2 23.2 11.9 8.4 17.4 25.1 14.4 15.4 30.7 14.0 13.9 21.5 12.6 12.7 15.4 10.6 12.2 24.0 13.2 10.4 11.5 16.5 10.8 11.7 38.0 31.1 11.8 18.1 22.0 9.3 8.6 8.9 15.8 24.5 22.5 15.3 83.8 19.9 21.8 7.0 22.9 17.5 17.1 17.7 12.4 18.3 20.7 15.8 21.2 28.4 18.8 24.6 14.6 21.4 16.9 14.8 12.2 24.7 14.6 15.6 22.5 14.4 13.8 24.8 26.2 16.4 21.2 24.4 14.2 59.9 12.7 19.4 20.7 19.5 21.9 2.6 18.0 14.6 15.8 28.6 15.1 23.5 16.7 24.6 19.7 36.8 65.2 18.5 18.5 15.9 16.6 27.7 21.8 9.5 29.5 27.6 16.7 23.6 19.2 45.7 21.4 30.0 0.0 0.4 0.5 0.6 0.6 0.5 0.4 0.4 0.7 0.5 1.1 0.3 0.7 0.4 0.1 0.5 0.4 0.9 0.1 19.4 19.8 27.0 17.2 18.5 26.3 17.4 25.1 21.5 16.5 31.1 15.8 18.6 19.2 20.2 53.8 9.7 23.2 7.8 13.6 14.2 20.1 31.0 20.1 23.1 30.0 19.7 35.0 39.6 11.3 12.6 18.2 3.9 18.3 66.7 31.2 24.9 19.0 19.9 18.7 85.7 23.8 9.6 22.2 13.3 18.4 6.3 19.6 37.9 42.3 12.2 35.3 86.1 15.8 20.3 23.0 12.8 17.4 15.2 11.7 17.8 72.1 15.5 18.4 7.2 82.4 59.9 20.5 9.2 24.5 9.8 13.0 16.2 27.5 27.2 22.1 0.0 30.6 14.7 36.2 6.3 17.5 29.1 11.2 9.6 22.7 20.4 12.2 KLHDC8A FLJ10748 ENSG00000162873 "Kelch domain containing 8A" Q8IYD2 1 205336061-205357090 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "ovary: 284.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 50.8;Granulosa cells: 97.0;Muller glia cells: 19.8;Peritubular cells: 21.1;Theca cells: 44.6" "Group enriched" "Detected in many" 5 "glioma: 45.7;thyroid cancer: 14.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 4.2;HAP1: 8.7;NTERA-2: 2.1;SCLC-21H: 8.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 40: Granulosa cells - Unknown function" "unprognostic (1.58e-1)" "unprognostic (1.25e-1)" "unprognostic (4.18e-2)" "unprognostic (4.80e-2)" "unprognostic (3.43e-2)" "unprognostic (3.21e-1)" "unprognostic (2.63e-2)" "unprognostic (2.97e-1)" "unprognostic (4.92e-1)" "unprognostic (8.37e-3)" "unprognostic (7.39e-3)" "unprognostic (4.03e-2)" "unprognostic (1.84e-7)" "unprognostic (4.53e-3)" "unprognostic (5.83e-2)" "prognostic favorable (8.01e-4)" "unprognostic (1.20e-2)" 0.1 26.5 9.3 0.4 7.3 6.5 0.5 15.0 14.3 2.4 4.6 2.8 0.8 1.6 0.7 4.5 13.9 0.5 0.6 13.9 13.0 0.5 0.2 0.2 0.2 16.6 11.0 284.0 2.1 0.6 18.0 0.0 17.1 0.4 0.6 26.4 1.4 0.2 0.1 0.5 0.8 2.5 11.0 0.3 6.8 6.4 18.5 0.3 3.4 0.0 1.2 0.4 2.5 4.3 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.2 8.7 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 8.7 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.3 7.3 15.0 14.3 13.9 13.0 16.6 11.0 17.1 11.0 18.5 4.3 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 50.8 0.1 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.1 2.1 7.1 11.6 1.2 0.0 0.0 7.6 0.0 0.2 0.0 97.0 0.4 0.0 0.0 5.0 8.9 0.0 0.0 0.0 0.0 0.2 5.3 0.2 0.0 0.0 0.0 19.8 0.0 3.0 0.2 0.3 0.0 21.1 0.5 0.0 0.0 0.2 0.1 4.8 0.0 0.0 8.1 0.8 5.0 0.0 0.0 0.0 0.0 44.6 0.0 0.0 KLHL13 "BKLHD2, FLJ10262, KIAA1309" ENSG00000003096 "Kelch like family member 13" Q9P2N7 X 117897813-118117340 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 31.4" "Cell type enhanced" "Detected in many" "Distal tubular cells: 29.4;Inhibitory neurons: 29.3;Microglial cells: 30.9;Oligodendrocyte precursor cells: 102.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 7.3;plasmacytoid DC: 4.1" "Group enriched" "Detected in many" 5 "dendritic cells: 4.1;granulocytes: 7.3" "Cell line enhanced" "Detected in many" "HAP1: 33.8;HeLa: 57.3;RH-30: 37.2;RPTEC TERT1: 106.0;SH-SY5Y: 94.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046039, HPA059901" Approved Approved Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 68: Oligodendrocytes - Mixed function" Cytosol "HPA046039: AB_2679514, HPA059901: AB_2684155" "unprognostic (1.11e-1)" "unprognostic (2.20e-1)" "unprognostic (1.03e-1)" "unprognostic (6.09e-2)" "unprognostic (1.07e-2)" "unprognostic (9.54e-2)" "unprognostic (7.22e-2)" "unprognostic (5.52e-2)" "unprognostic (1.41e-1)" "unprognostic (2.54e-1)" "unprognostic (6.91e-2)" "unprognostic (1.52e-1)" "unprognostic (3.09e-3)" "unprognostic (1.24e-2)" "unprognostic (3.90e-2)" "unprognostic (1.53e-1)" "unprognostic (2.31e-1)" 2.7 7.3 4.6 2.6 11.1 0.4 24.6 2.7 4.8 20.5 5.5 5.4 3.1 31.4 7.3 5.9 10.7 5.6 7.8 3.2 5.9 16.0 4.7 1.4 0.6 5.9 10.3 7.4 4.6 3.4 2.2 0.8 6.4 6.2 3.9 4.2 2.2 12.3 3.6 1.1 4.8 29.3 4.0 1.6 3.2 3.6 5.9 5.0 0.8 5.6 1.2 7.5 5.0 3.8 1.1 0.4 6.9 14.5 0.1 0.0 0.2 0.5 0.0 0.4 0.0 9.1 0.1 0.0 16.5 0.0 0.7 16.9 33.8 5.6 0.0 0.0 12.9 0.4 57.3 0.1 0.8 1.1 2.2 1.8 2.3 0.2 0.7 6.9 25.8 0.0 0.0 0.0 0.0 1.4 5.9 1.6 13.4 0.0 9.6 0.0 37.2 0.1 106.0 4.0 0.0 94.3 0.5 1.2 0.9 2.7 20.9 0.2 0.7 2.4 2.9 2.0 8.6 0.4 0.0 0.2 10.2 0.0 4.1 2.4 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.0 0.6 0.6 0.0 1.1 0.0 4.1 0.2 0.3 4.6 11.1 2.7 4.8 3.2 5.9 5.9 10.3 6.4 4.0 5.9 3.8 0.7 0.0 0.0 13.7 0.0 0.8 6.8 5.4 12.0 6.2 2.4 19.9 10.5 0.0 4.8 1.8 0.0 0.2 0.1 1.2 29.4 1.1 0.3 8.0 22.7 1.9 1.2 1.3 8.0 3.4 0.1 8.7 0.0 1.3 0.0 10.0 8.6 1.3 0.6 0.0 29.3 2.1 0.0 0.0 1.2 0.9 6.2 1.0 1.8 30.9 0.2 7.2 0.0 102.5 12.3 0.7 3.4 1.9 0.1 2.7 2.9 12.7 22.3 1.2 6.6 18.1 5.3 1.8 10.6 4.8 0.4 0.0 0.6 6.4 4.1 3.6 KLHL26 ENSG00000167487 "Kelch like family member 26" Q53HC5 19 18637025-18671721 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023074 Uncertain NA NA "Cluster 15: NK-cells - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "HPA023074: AB_2671060" "prognostic favorable (5.01e-4)" "unprognostic (1.50e-3)" "unprognostic (2.54e-2)" "unprognostic (2.26e-3)" "unprognostic (1.23e-2)" "unprognostic (2.70e-3)" "unprognostic (1.62e-2)" "unprognostic (5.32e-3)" "unprognostic (9.12e-2)" "unprognostic (1.77e-2)" "unprognostic (9.04e-3)" "unprognostic (9.76e-2)" "prognostic favorable (1.25e-6)" "unprognostic (1.82e-2)" "unprognostic (2.76e-1)" "unprognostic (3.92e-2)" "unprognostic (4.49e-2)" 7.2 4.5 9.2 2.6 10.2 3.1 6.0 7.4 11.9 6.0 1.7 5.8 1.9 5.5 2.2 3.6 6.6 1.7 7.0 9.6 6.9 4.2 3.7 4.5 2.4 7.4 7.0 6.6 5.2 2.6 6.3 1.4 5.2 5.7 1.3 1.6 4.1 3.3 8.1 5.8 4.0 1.5 6.4 3.9 5.7 4.4 7.9 1.9 7.2 3.3 1.1 5.2 4.8 7.9 6.0 2.6 2.2 3.7 5.0 2.2 8.0 2.2 0.6 2.5 1.6 3.6 4.9 4.3 7.5 1.8 1.9 4.5 2.9 1.4 1.1 3.1 7.6 2.2 4.5 3.3 6.4 3.2 3.6 2.2 2.5 1.3 0.9 2.4 1.5 5.0 5.0 4.9 0.9 5.7 7.8 4.8 3.8 3.4 9.0 7.2 0.2 4.5 2.5 2.9 2.4 5.0 5.5 4.0 2.8 1.3 3.6 6.4 4.7 1.2 1.1 0.2 4.2 7.4 4.6 6.5 4.4 5.6 1.7 0.6 1.5 0.8 1.5 0.9 2.4 1.3 1.5 1.8 1.3 1.5 1.5 1.5 1.1 4.4 0.9 1.2 0.6 1.3 9.2 10.2 7.4 11.9 9.6 6.9 7.4 7.0 5.2 6.4 7.9 7.9 2.3 3.2 1.1 7.8 1.9 1.0 1.7 2.1 7.4 4.4 4.2 3.6 3.3 5.7 1.1 0.0 4.2 3.1 2.2 2.4 13.7 3.9 0.8 2.1 2.2 2.2 6.7 2.7 3.3 2.3 1.4 4.7 3.6 2.9 11.4 3.1 2.9 4.0 4.0 6.7 2.1 3.3 6.1 3.5 2.2 0.7 3.1 2.5 1.8 3.7 4.9 11.6 1.0 1.0 3.0 2.8 2.1 2.2 0.7 1.6 1.8 3.4 1.2 2.3 6.6 8.9 4.9 3.2 6.5 3.3 1.8 1.9 3.7 1.7 3.6 1.0 KLHL4 "DKELCHL, KHL4, KIAA1687" ENSG00000102271 "Kelch like family member 4" Q9C0H6 X 87517409-87670050 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 26.5;brain: 21.3" "Group enriched" "Detected in some" 4 "Oligodendrocytes: 286.2;Theca cells: 109.4" "Cancer enriched" "Detected in some" 8 "glioma: 9.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 14.7;GAMG: 18.2;HUVEC TERT2: 32.0;NTERA-2: 24.3;SuSa: 17.8;TIME: 34.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029192 Approved Supported "Microtubules,Centriolar satellite" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Microtubules "Centriolar satellite" "HPA029192: AB_10602341" "unprognostic (6.70e-2)" "unprognostic (2.20e-1)" "unprognostic (8.74e-2)" "unprognostic (2.84e-3)" "unprognostic (1.48e-2)" "unprognostic (5.90e-2)" "unprognostic (1.71e-2)" "unprognostic (1.89e-2)" "unprognostic (5.21e-2)" "unprognostic (2.63e-1)" "unprognostic (5.98e-2)" "unprognostic (1.30e-1)" "prognostic unfavorable (8.08e-5)" "unprognostic (2.40e-4)" "unprognostic (1.05e-1)" "unprognostic (5.87e-2)" "unprognostic (7.25e-4)" 1.3 26.5 5.3 0.4 10.2 0.0 0.9 7.3 7.1 1.2 0.6 0.3 0.1 3.0 0.3 0.5 2.5 1.5 0.8 5.2 5.7 1.1 0.6 0.8 0.4 9.6 7.5 7.9 0.3 0.0 0.0 0.1 9.5 0.3 0.3 2.3 0.0 1.4 0.3 0.1 0.3 5.1 7.5 1.3 0.3 7.0 6.7 0.1 0.6 0.3 0.1 0.9 0.2 21.3 0.0 3.6 14.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 18.2 0.0 0.1 0.9 0.0 1.4 0.4 0.0 2.6 0.0 11.0 0.2 0.0 1.6 4.7 6.0 1.3 11.6 32.0 0.0 0.2 2.5 8.1 0.0 0.0 0.0 24.3 0.1 5.7 0.0 8.9 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 17.8 0.0 0.1 34.4 0.0 5.6 0.0 0.5 0.2 0.0 0.1 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 5.3 10.2 7.3 7.1 5.2 5.7 9.6 7.5 9.5 7.5 6.7 21.3 1.7 0.0 0.0 2.0 0.0 0.1 0.0 0.1 0.0 3.6 0.0 0.0 1.5 0.0 0.0 0.0 8.4 0.0 0.2 0.0 0.0 0.0 0.7 0.2 0.1 15.0 0.0 0.0 44.4 0.0 0.0 4.4 0.0 0.1 0.0 4.5 14.3 0.2 0.1 0.0 6.6 0.0 0.0 0.3 0.3 1.5 0.9 0.1 0.0 4.7 0.0 1.5 0.0 36.2 286.2 0.1 0.0 1.5 0.1 0.0 0.0 3.4 2.2 4.1 0.0 1.2 0.5 0.4 0.4 0.0 0.3 0.0 0.7 109.4 0.0 0.0 KLHL40 "KBTBD5, NEM8, SRYP" ENSG00000157119 "Kelch like family member 40" Q2TBA0 3 42685537-42692544 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Developmental protein" "Disease variant, Nemaline myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 62 "skeletal muscle: 431.2;tongue: 162.3" "Group enriched" "Detected in some" 17 "Early spermatids: 5.0;Late spermatids: 10.7;Skeletal myocytes: 16.3" "Cancer enhanced" "Detected in single" "head and neck cancer: 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA024463, HPA052201" Enhanced NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 37: Myocytes - Muscle contraction" "HPA024463: AB_1852095, HPA052201: AB_2681759" "unprognostic (1.13e-1)" "unprognostic (3.28e-2)" "unprognostic (1.19e-1)" "unprognostic (2.09e-1)" "unprognostic (7.85e-2)" "unprognostic (2.50e-1)" "unprognostic (4.04e-1)" 0.1 0.0 0.1 0.0 0.4 0.0 0.1 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 4.7 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.2 3.0 0.0 0.1 4.2 0.0 431.2 0.7 0.0 0.0 0.1 0.0 0.0 1.7 0.3 0.0 0.1 162.3 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.1 0.3 0.1 0.1 0.2 0.2 0.2 0.1 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 16.3 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KLHL42 "Ctb9, KIAA1340, KLHDC5" ENSG00000087448 "Kelch like family member 42" Q9P2K6 12 27780048-27803040 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Peritubular cells: 172.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020979 Uncertain NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 5: NTERA-2 - Transcription" "Cluster 47: Cytotrophoblasts - Unknown function" "HPA020979: AB_1852559" "unprognostic (4.68e-2)" "unprognostic (1.00e-1)" "unprognostic (3.30e-1)" "unprognostic (1.31e-1)" "unprognostic (1.34e-1)" "unprognostic (5.46e-2)" "unprognostic (7.38e-3)" "unprognostic (8.82e-2)" "unprognostic (1.50e-2)" "unprognostic (4.92e-2)" "unprognostic (4.89e-3)" "unprognostic (1.12e-1)" "prognostic unfavorable (2.98e-4)" "unprognostic (2.22e-1)" "unprognostic (1.36e-1)" "unprognostic (1.54e-2)" "unprognostic (2.16e-1)" 8.7 7.3 10.8 11.6 12.1 4.6 9.4 8.3 12.7 11.5 1.6 23.0 8.5 19.0 9.6 13.2 13.4 11.7 6.6 13.2 12.3 7.5 6.4 9.2 9.4 9.2 8.9 8.2 21.3 12.3 9.8 14.1 9.3 14.8 12.1 13.9 6.1 18.8 2.6 9.6 10.0 23.1 9.6 8.7 12.2 10.3 11.3 6.6 10.2 2.6 8.1 21.7 9.7 16.1 11.8 14.9 24.2 22.2 25.9 15.9 23.9 22.5 17.0 16.4 17.6 10.5 16.0 14.6 9.5 14.9 12.6 23.8 11.9 15.6 16.4 19.5 14.5 19.4 29.3 6.9 12.0 17.1 15.2 15.7 12.9 14.3 20.4 21.1 18.7 12.0 6.3 8.0 13.3 10.6 11.9 17.1 34.6 7.6 20.6 13.0 22.1 2.8 9.8 19.2 8.4 24.3 16.6 13.2 17.9 33.8 20.0 15.6 30.2 22.8 13.7 27.7 25.1 9.9 5.5 25.5 14.6 11.2 16.2 0.0 0.5 0.2 1.0 0.4 1.0 0.1 1.1 0.7 0.3 0.5 0.8 1.1 0.0 0.8 0.7 0.7 1.8 0.3 10.8 12.1 8.3 12.7 13.2 12.3 9.2 8.9 9.3 9.6 11.3 16.1 16.2 19.2 16.8 33.0 9.3 23.1 12.3 14.9 29.0 49.8 17.0 25.1 9.1 10.0 12.6 7.3 22.9 69.5 13.9 14.6 3.9 8.9 1.7 9.3 28.8 18.8 27.7 16.8 61.5 20.2 19.8 26.2 15.3 23.9 11.4 25.5 19.2 24.7 13.2 35.3 78.9 12.8 12.2 8.8 11.7 6.0 35.1 8.6 28.4 17.8 16.7 73.9 32.0 63.8 95.5 11.2 7.2 172.3 7.6 14.0 8.0 8.8 7.6 25.2 65.7 33.8 34.6 5.0 12.3 13.1 20.5 20.5 14.7 27.9 11.0 7.4 KLK11 "PRSS20, TLSP" ENSG00000167757 "Kallikrein related peptidase 11" Q9UBX7 19 51022216-51028039 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 324.2;skin 1: 239.8;vagina: 186.5" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 152.1;Club cells: 217.9;Late spermatids: 339.0;Prostatic glandular cells: 234.8;Squamous epithelial cells: 176.4;Suprabasal keratinocytes: 217.1;Urothelial cells: 186.1" "Cancer enhanced" "Detected in many" "prostate cancer: 53.3" "Region enhanced" "Detected in single" "hippocampal formation: 1.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "EFO-21: 13.0;HaCaT: 41.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" CAB026340 Approved "Secreted in other tissues" NA NA 1800000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "CAB026340: " "unprognostic (4.23e-2)" "unprognostic (1.50e-2)" "unprognostic (1.27e-1)" "prognostic favorable (3.78e-4)" "unprognostic (2.08e-2)" "unprognostic (4.67e-1)" "unprognostic (5.32e-2)" "unprognostic (3.72e-1)" "unprognostic (3.02e-1)" "prognostic unfavorable (4.17e-4)" "unprognostic (2.92e-2)" "unprognostic (4.16e-6)" "unprognostic (3.90e-2)" "unprognostic (2.73e-1)" "unprognostic (4.40e-2)" "unprognostic (2.53e-1)" 28.4 0.2 0.0 0.4 0.0 0.0 17.1 0.9 0.1 109.8 44.5 1.9 0.7 7.2 2.6 324.2 34.2 59.3 2.0 1.7 0.0 0.3 0.8 18.9 0.0 0.2 0.1 1.6 89.1 0.0 8.8 0.0 0.3 64.9 0.6 0.7 169.5 4.2 1.9 239.8 1.4 0.3 0.0 0.1 113.3 14.4 0.6 2.5 0.4 0.3 27.2 1.4 186.5 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 6.4 0.1 13.0 0.0 0.0 41.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.1 4.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 1.7 0.0 0.2 0.1 0.3 0.0 0.6 0.0 0.2 86.6 10.4 0.0 0.4 106.9 152.1 131.6 13.1 0.2 33.4 35.3 0.8 88.6 217.9 0.0 0.0 0.0 0.0 0.1 0.0 9.2 111.6 4.7 1.1 3.8 20.3 0.0 0.0 130.2 0.0 9.1 91.3 15.6 1.3 0.0 0.0 0.0 0.3 0.0 0.0 10.7 118.0 0.0 11.4 339.0 2.8 1.8 8.8 0.0 0.1 0.1 0.0 0.0 0.0 79.4 0.0 0.4 0.5 234.8 0.1 0.0 26.9 1.3 0.0 0.2 7.9 2.1 2.5 176.4 217.1 0.0 1.7 0.0 0.4 186.1 KLK12 KLK-L5 ENSG00000186474 "Kallikrein related peptidase 12" Q9UKR0 19 51029092-51035230 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "cervix: 108.5;esophagus: 208.6;salivary gland: 64.7;vagina: 99.4" "Cell type enhanced" "Detected in some" "Early spermatids: 30.7;Enteroendocrine cells: 40.3;Intestinal goblet cells: 24.9;Ionocytes: 14.2;Late spermatids: 34.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 17.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" CAB025473 Uncertain "Secreted in other tissues" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "CAB025473: " "unprognostic (2.84e-1)" "unprognostic (1.41e-1)" "unprognostic (1.08e-3)" "unprognostic (1.15e-1)" "unprognostic (5.80e-3)" "unprognostic (4.99e-3)" "unprognostic (3.18e-1)" "unprognostic (1.41e-1)" "unprognostic (4.64e-2)" "unprognostic (1.51e-1)" "unprognostic (1.56e-1)" "prognostic favorable (8.01e-4)" "unprognostic (8.50e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 108.5 2.2 2.1 4.0 0.0 0.0 208.6 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 3.6 0.0 0.1 0.5 0.8 0.0 64.7 0.0 0.0 0.6 5.8 0.1 0.0 0.0 0.4 0.5 0.0 0.1 0.1 0.0 8.9 0.0 99.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.5 0.5 0.2 0.0 2.3 0.0 0.0 0.0 0.1 0.9 0.0 0.0 30.7 0.0 0.0 0.0 40.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.9 14.2 0.0 0.0 34.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.9 0.4 0.0 1.7 0.0 0.0 0.0 0.0 0.4 0.2 8.4 0.0 0.0 0.0 0.0 1.3 1.7 KPNA3 "hSRP1, IPOA4, SRP1gamma, SRP4" ENSG00000102753 "Karyopherin subunit alpha 3" O00505 13 49699320-49792682 "Predicted intracellular proteins, Transporters" "Host-virus interaction, Protein transport, Transport, Viral penetration into host nucleus, Virus entry into host cell" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 145.4;tongue: 94.2" "Cell type enhanced" "Detected in all" "Early spermatids: 316.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046852, HPA077643" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 39: CACO-2 - Unknown function" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA046852: AB_2679840, HPA077643: " "unprognostic (4.20e-2)" "prognostic unfavorable (2.80e-4)" "unprognostic (3.69e-2)" "unprognostic (1.23e-1)" "prognostic favorable (2.03e-4)" "unprognostic (6.27e-3)" "unprognostic (6.79e-2)" "unprognostic (9.40e-3)" "unprognostic (1.56e-2)" "unprognostic (4.57e-3)" "unprognostic (3.93e-3)" "unprognostic (4.66e-2)" "prognostic unfavorable (3.81e-4)" "unprognostic (9.78e-2)" "unprognostic (7.83e-2)" "unprognostic (5.68e-3)" "unprognostic (4.60e-3)" 20.8 10.6 13.6 16.9 15.3 29.7 11.7 14.3 19.6 13.7 9.3 17.0 12.3 13.8 11.3 25.4 12.4 14.6 31.9 16.0 15.0 13.8 23.4 17.2 18.4 14.4 13.5 8.3 10.4 12.6 7.1 14.9 14.3 15.8 16.6 33.4 10.4 19.1 145.4 16.2 12.2 25.6 16.1 13.6 13.4 28.5 15.9 19.9 19.2 94.2 20.2 20.1 11.0 17.8 41.3 28.3 53.0 44.6 53.2 58.1 26.6 73.3 60.8 63.5 46.0 86.2 37.6 89.2 14.4 86.6 42.7 47.1 64.1 59.5 105.2 53.8 44.7 65.3 25.4 101.1 51.8 98.7 40.6 42.9 42.3 53.3 69.8 41.7 79.7 36.9 36.7 23.4 88.8 19.1 53.2 53.7 61.4 57.8 19.7 68.6 52.1 27.3 39.1 33.8 22.2 34.8 27.1 33.3 29.5 43.8 19.8 39.3 73.0 46.7 37.5 43.0 49.8 18.8 27.9 76.7 28.4 44.9 47.2 10.3 3.8 3.6 6.7 4.5 9.3 4.9 6.7 6.6 4.2 2.8 6.4 5.9 2.2 6.7 6.0 2.3 8.5 3.4 13.6 15.3 14.3 19.6 16.0 15.0 14.4 13.5 14.3 16.1 15.9 17.8 44.3 67.3 33.8 64.9 35.2 43.1 30.5 21.4 43.9 29.9 23.4 15.0 76.5 21.5 25.7 12.9 33.3 15.5 31.8 26.0 17.6 49.0 316.7 57.4 35.7 44.2 30.5 39.1 90.6 53.7 17.7 30.0 27.0 40.7 33.0 25.4 30.4 36.2 33.1 52.2 83.9 18.4 20.3 37.3 38.7 168.8 22.1 41.9 19.6 55.3 47.1 49.0 35.0 73.4 85.6 51.7 15.0 50.0 36.9 41.7 14.3 28.1 45.8 65.7 26.3 29.1 32.1 66.1 31.8 52.9 49.9 10.5 38.6 61.9 24.9 33.1 KRBOX1 ENSG00000240747 "KRAB box domain containing 1" C9JBD0 3 42809483-42942792 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 24 "testis: 197.8" "Cell type enhanced" "Detected in many" "Early spermatids: 250.9;Late spermatids: 111.3;Spermatocytes: 883.9;Spermatogonia: 176.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 4.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BJ hTERT+: 22.2;CAPAN-2: 50.0;EFO-21: 22.6;GAMG: 35.2;hTEC/SVTERT24-B: 33.7;hTERT-HME1: 23.0;U-2197: 67.7" HPA046901 Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 83: Testis - Spermatogenesis" "Cluster 18: U-2197 - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "Golgi apparatus" "HPA046901: AB_2797232" "unprognostic (2.62e-1)" "unprognostic (1.19e-1)" "unprognostic (1.82e-1)" "unprognostic (1.53e-3)" "unprognostic (7.63e-3)" "unprognostic (1.24e-2)" "unprognostic (1.05e-1)" "unprognostic (1.11e-1)" "unprognostic (3.46e-2)" "unprognostic (2.27e-1)" "unprognostic (5.64e-2)" "unprognostic (2.95e-2)" "unprognostic (9.66e-2)" "unprognostic (2.27e-2)" "unprognostic (1.04e-1)" "unprognostic (1.31e-1)" "unprognostic (2.28e-1)" 3.4 4.7 2.9 0.2 2.9 0.5 3.9 3.1 3.8 5.8 2.8 4.9 1.7 5.3 8.1 4.3 3.9 1.2 3.8 3.0 3.0 6.0 0.6 1.5 0.9 3.1 2.9 6.9 3.9 0.8 4.0 1.3 2.9 3.6 2.0 1.9 2.3 5.3 1.6 5.1 1.8 4.7 2.9 1.2 2.7 197.8 2.9 1.5 5.2 1.1 1.6 3.8 3.2 3.1 0.0 0.0 0.0 0.0 0.0 0.0 1.8 8.7 22.2 0.2 0.0 0.1 50.0 0.0 22.6 1.8 35.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 9.7 0.0 33.7 23.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5.9 0.0 0.0 0.0 0.0 0.0 17.0 0.0 67.7 0.0 7.4 2.6 0.0 3.8 0.0 1.4 0.0 0.3 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.4 0.0 4.0 0.7 1.0 0.3 0.0 2.9 2.9 3.1 3.8 3.0 3.0 3.1 2.9 2.9 2.9 2.9 3.1 2.2 0.0 2.6 1.6 0.1 0.0 2.6 0.0 0.6 8.8 4.2 11.3 5.6 2.8 1.8 5.5 2.1 12.0 0.2 0.4 19.6 4.2 250.9 4.4 7.7 1.6 0.0 0.0 0.8 12.0 10.1 6.1 0.0 2.5 0.0 3.8 1.4 1.0 2.2 1.7 1.4 1.4 0.0 0.0 0.0 111.3 20.2 1.0 0.0 1.0 0.0 18.3 1.0 1.5 1.0 6.8 3.2 13.5 0.0 1.8 1.2 3.1 0.7 8.8 13.1 5.2 6.9 883.9 176.0 0.6 0.0 9.0 0.2 14.3 2.8 1.0 KRT23 "CK23, DKFZP434G032, HAIK1, K23, MGC26158" ENSG00000108244 "Keratin 23" Q9C075 17 40922700-40937646 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "salivary gland: 147.7;skin 1: 172.3" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 1328.6;Cytotrophoblasts: 679.8;Prostatic glandular cells: 2203.0;Syncytiotrophoblasts: 3890.8;Urothelial cells: 1590.3" "Cancer enhanced" "Detected in many" "urothelial cancer: 61.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 14 "HBEC3-KT: 9.6;Hep G2: 11.0;SuSa: 7.1;T-47d: 16.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA012050, HPA016959, CAB017091" Approved Approved "Intermediate filaments,Cytosol" NA NA 590000 "Cluster 52: Eosinophils - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 6: T47d - Mammary gland" "Cluster 22: Epithelial cell types - Mixed function" "Intermediate filaments" Cytosol "CAB017091: , HPA012050: AB_1852226, HPA016959: AB_1852228" "unprognostic (1.62e-1)" "unprognostic (5.29e-2)" "unprognostic (4.35e-2)" "unprognostic (6.18e-3)" "unprognostic (1.45e-2)" "unprognostic (2.83e-1)" "unprognostic (5.22e-2)" "unprognostic (6.84e-3)" "unprognostic (2.74e-1)" "unprognostic (2.15e-2)" "unprognostic (8.96e-2)" "unprognostic (1.56e-1)" "unprognostic (8.22e-2)" "unprognostic (6.78e-2)" "unprognostic (1.40e-1)" "unprognostic (2.99e-1)" "prognostic unfavorable (8.26e-4)" 0.4 0.0 0.0 0.3 0.0 1.1 15.7 0.0 0.0 6.8 0.0 0.1 0.2 1.1 2.1 6.5 3.0 1.5 0.2 0.0 0.0 0.6 1.0 1.4 0.0 0.0 0.0 0.1 3.6 0.1 2.8 15.6 0.0 20.7 0.0 0.6 147.7 0.4 0.3 172.3 0.2 0.0 0.0 3.0 0.2 21.7 0.0 0.4 0.1 0.4 2.5 4.4 10.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.1 0.0 0.0 0.2 0.0 9.6 0.0 0.0 0.0 0.0 0.1 11.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.6 0.0 7.1 16.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.3 0.3 0.3 4.6 1328.6 242.1 0.6 0.0 78.0 27.9 0.4 12.8 390.5 3.7 0.0 679.8 1.1 0.1 1.9 462.9 66.2 49.8 7.8 15.1 7.1 0.0 0.5 0.8 109.3 15.0 0.0 66.4 0.0 0.0 0.0 0.0 63.8 0.0 0.3 0.7 57.0 0.0 0.7 10.6 0.6 3.0 5.4 0.0 5.4 15.8 0.0 0.5 0.3 17.7 1.1 0.7 0.0 2203.0 0.0 0.4 275.0 0.2 0.0 0.0 48.4 62.1 0.7 7.9 8.1 3890.8 7.6 0.1 0.9 1590.3 KRT25 KRT25A ENSG00000204897 "Keratin 25" Q7Z3Z0 17 40748021-40755331 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Hypotrichosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 42 "skin 1: 112.3" "Cell type enhanced" "Detected in some" "Early spermatids: 7.8;Late spermatids: 9.2;Spermatogonia: 2.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "RPTEC TERT1: 1.3" "Region enriched" "Detected in some" 7 "cerebellum: 8.6" "Group enriched" "Detected in some" 5 "cerebral cortex: 7.3;hippocampal formation: 4.8" "HPA053977, HPA058943" Enhanced Approved Vesicles NA NA "Cluster 61: Skin - Cornification" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 34: Spermatids - Unknown function" Vesicles "HPA053977: AB_2682329, HPA058943: AB_2683859" "unprognostic (8.19e-2)" "unprognostic (5.89e-8)" "unprognostic (1.79e-1)" 2.6 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 112.3 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KRT34 "Ha-4, KRTHA4" ENSG00000131737 "Keratin 34" O76011 17 41377650-41382403 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 25 "skin 1: 66.6" "Group enriched" "Detected in some" 8 "Early spermatids: 5.4;Late spermatids: 15.6" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "BJ: 201.8" "Not detected" "Not detected" "HPA055194, HPA072208" Enhanced Approved Nucleoplasm,Vesicles NA NA 170000000 "Cluster 61: Skin - Cornification" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Vesicles" "HPA055194: AB_2682733, HPA072208: AB_2686494" "unprognostic (2.52e-1)" "unprognostic (2.14e-1)" "unprognostic (9.03e-2)" "unprognostic (2.94e-1)" "unprognostic (2.25e-1)" "unprognostic (1.19e-1)" "unprognostic (2.86e-3)" "unprognostic (5.12e-7)" "unprognostic (3.84e-2)" 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 66.6 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.3 0.0 0.0 0.0 1.1 1.8 0.0 1.6 0.0 0.0 0.0 0.1 1.9 0.0 201.8 8.8 23.5 46.4 0.0 0.1 0.0 0.0 25.1 0.1 0.0 0.0 0.0 42.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 8.2 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.4 6.1 26.3 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.4 0.3 1.2 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.3 0.1 0.0 0.3 0.0 0.0 LACC1 "C13orf31, FAMIN, FLJ38725" ENSG00000179630 "Laccase domain containing 1" Q8IV20 13 43879284-43893932 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Immunity, Inflammatory response, Innate immunity" "Hydrolase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.4" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 39.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 3.0;eosinophil: 3.1;intermediate monocyte: 5.2;myeloid DC: 2.7;non-classical monocyte: 8.0" "Group enriched" "Detected in many" 4 "dendritic cells: 2.7;granulocytes: 3.1;monocytes: 8.0" "Cell line enhanced" "Detected in many" "HMC-1: 37.1;TIME: 118.2" "Low region specificity" "Detected in all" "CAB034228, HPA040150, HPA044211" Uncertain NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 65: Brain - Ion transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 4: Macrophages - Innate immune response" "CAB034228: AB_1564163, HPA040150: AB_10963540, HPA044211: AB_10961258" "unprognostic (2.48e-1)" "unprognostic (3.27e-2)" "unprognostic (4.54e-2)" "unprognostic (3.31e-3)" "unprognostic (1.17e-2)" "unprognostic (3.90e-2)" "unprognostic (6.41e-3)" "unprognostic (4.43e-2)" "unprognostic (3.03e-3)" "unprognostic (1.78e-2)" "unprognostic (6.06e-3)" "unprognostic (2.02e-1)" "unprognostic (3.93e-2)" "unprognostic (3.30e-1)" "unprognostic (9.36e-3)" "unprognostic (2.22e-1)" "unprognostic (1.18e-1)" 6.4 6.6 12.7 12.2 22.3 1.9 5.4 10.8 20.6 4.5 6.8 10.3 9.9 3.9 3.2 6.8 3.2 9.8 10.1 11.7 13.6 4.8 7.2 6.4 8.8 13.9 14.5 3.4 3.5 9.9 2.8 6.1 15.2 5.4 13.3 0.8 4.6 4.9 1.4 4.8 13.8 5.8 12.5 7.2 6.8 9.4 17.3 6.5 3.5 1.2 8.3 11.1 2.9 27.4 4.7 2.5 1.3 0.0 2.7 12.3 9.5 10.3 25.7 2.8 3.9 5.3 10.5 9.9 2.3 13.8 6.0 6.7 0.3 2.9 4.5 6.6 1.7 12.3 2.6 1.9 12.5 2.9 37.1 16.3 8.5 10.3 12.6 3.4 5.9 1.1 0.0 7.1 6.4 2.3 0.3 3.7 0.9 2.6 2.2 2.3 0.0 5.2 7.4 5.5 1.6 2.5 3.4 1.2 4.9 6.8 1.5 6.2 118.2 3.5 1.1 18.8 0.1 0.0 0.0 2.4 10.0 3.7 8.0 1.0 3.0 3.1 0.7 5.2 0.8 0.8 0.6 0.6 2.7 1.0 0.2 0.3 0.1 0.4 8.0 0.5 0.8 1.0 12.7 22.3 10.8 20.6 11.7 13.6 13.9 14.5 15.2 12.5 17.3 27.4 4.6 12.8 6.8 1.0 5.9 5.7 8.4 8.1 3.4 0.5 5.1 4.6 24.2 4.3 7.8 11.0 0.0 6.5 1.0 7.6 1.9 5.5 1.3 5.1 3.4 7.4 5.4 1.7 2.1 3.8 4.3 4.5 2.0 8.5 8.2 9.7 5.0 5.1 15.3 0.0 6.2 4.4 6.1 17.6 10.3 3.1 2.1 24.2 1.8 1.9 7.8 2.0 1.0 2.0 39.2 8.0 11.2 1.5 0.5 11.4 10.5 8.2 7.2 0.2 6.6 5.3 6.0 17.1 16.7 8.4 10.2 9.2 4.3 4.6 6.7 10.2 LALBA LYZL7 ENSG00000167531 "Lactalbumin alpha" P00709 12 48567684-48570066 "Cancer-related genes, Metabolic proteins, Predicted secreted proteins" "Lactose biosynthesis" "Milk protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 926 "breast: 2187.5" "Cell type enriched" "Detected in some" 160 "Breast glandular cells: 48911.9" "Cancer enriched" "Detected in single" 599 "breast cancer: 29.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB026343, HPA029855, HPA029856" Enhanced "Secreted in female reproductive system" NA NA 91000 "Cluster 5: Breast - Unknown function" "Cluster 30: Mammary glandular cells - Lactation" "CAB026343: , HPA029855: AB_2673222, HPA029856: AB_10671362" "unprognostic (7.85e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 2187.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 166.6 0.0 0.0 0.0 46.7 0.0 0.0 0.0 0.0 0.0 48911.9 305.6 0.0 0.0 0.0 0.0 0.0 0.0 108.5 0.0 0.0 0.0 0.6 0.0 0.0 15.9 0.0 0.0 0.1 0.0 0.0 11.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.9 0.0 58.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.1 0.0 0.7 0.0 0.0 0.0 32.6 0.0 0.0 0.0 LAMA5 ENSG00000130702 "Laminin subunit alpha 5" O15230 20 62307955-62367312 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 76.9;Cytotrophoblasts: 104.4;Glandular and luminal cells: 82.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 114.9;CACO-2: 159.6;EFO-21: 114.4;HaCaT: 107.2;HeLa: 118.3;TIME: 138.4" "Low region specificity" "Detected in many" "HPA058389, CAB078157" Enhanced Approved Vesicles "Secreted to extracellular matrix" NA NA 1800000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 47: Cytotrophoblasts - Unknown function" Vesicles "CAB078157: AB_2665809, HPA058389: " "unprognostic (8.01e-2)" "unprognostic (2.47e-1)" "unprognostic (1.92e-2)" "unprognostic (3.42e-3)" "unprognostic (1.17e-1)" "unprognostic (9.90e-3)" "unprognostic (4.01e-3)" "unprognostic (5.45e-2)" "unprognostic (8.99e-2)" "unprognostic (1.34e-2)" "unprognostic (5.98e-3)" "unprognostic (2.98e-3)" "unprognostic (4.04e-2)" "unprognostic (9.86e-3)" "unprognostic (2.07e-1)" "unprognostic (9.76e-2)" "unprognostic (1.33e-2)" 27.1 11.8 4.7 5.0 2.2 1.3 27.0 15.2 7.0 26.3 18.9 66.7 5.3 31.3 1.2 24.5 31.8 7.9 26.6 2.4 2.0 32.7 13.2 43.9 3.0 3.2 1.9 9.3 13.9 4.8 12.1 20.0 2.5 36.7 1.2 0.6 17.8 15.4 11.0 36.0 19.9 7.3 0.6 14.0 25.1 4.6 9.3 2.7 28.6 2.8 1.9 32.6 30.2 0.4 15.1 114.9 2.2 14.8 2.7 31.0 85.9 4.2 2.2 3.3 0.6 159.6 59.1 1.3 114.4 0.1 3.6 107.2 3.1 45.8 0.2 0.3 6.5 3.8 118.3 46.1 9.9 0.0 16.6 1.6 29.6 7.9 8.0 5.7 15.0 0.0 7.0 1.7 0.0 22.3 0.1 0.4 7.3 19.3 65.9 0.2 1.4 12.8 28.6 70.3 1.1 44.5 63.2 62.2 1.2 11.6 62.0 0.9 138.4 1.6 41.2 0.7 18.9 0.8 0.2 0.6 31.7 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.7 2.2 15.2 7.0 2.4 2.0 3.2 1.9 2.5 0.6 9.3 0.4 60.2 76.9 37.1 19.9 6.9 17.1 16.0 56.8 52.9 3.6 16.7 20.8 20.5 12.8 43.9 38.6 8.4 104.4 3.9 0.6 0.0 28.6 4.3 35.5 11.7 49.6 2.4 6.1 5.9 4.5 23.3 13.0 6.1 82.0 2.5 0.9 18.9 12.7 13.1 3.3 12.7 0.3 14.2 0.6 5.4 1.3 9.9 2.2 1.8 10.3 1.1 8.2 1.0 3.5 1.3 13.2 0.1 19.5 8.5 21.9 0.0 12.2 49.6 1.8 26.3 11.0 39.4 0.6 1.7 23.4 12.6 57.3 2.2 1.7 0.6 27.5 LAMC3 DKFZp434E202 ENSG00000050555 "Laminin subunit gamma 3" Q9Y6N6 9 131009174-131094473 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 48.7" "Group enriched" "Detected in many" 4 "Leydig cells: 118.4;Peritubular cells: 364.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 4.0;EFO-21: 17.3;Hep G2: 6.1;SiHa: 6.7;U-2 OS: 5.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022814 Enhanced "Secreted to extracellular matrix" NA NA 1100000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 28: Placenta - Pregnancy" "Cluster 38: EFO-21 - Unknown function" "Cluster 52: Non-specific - Transcription" "HPA022814: AB_2670960" "unprognostic (9.77e-2)" "unprognostic (1.90e-1)" "unprognostic (9.55e-3)" "unprognostic (2.09e-1)" "unprognostic (2.15e-1)" "unprognostic (1.22e-2)" "unprognostic (1.38e-2)" "unprognostic (2.28e-3)" "unprognostic (6.27e-2)" "unprognostic (1.83e-1)" "unprognostic (1.58e-1)" "unprognostic (3.38e-1)" "unprognostic (1.27e-1)" "unprognostic (1.44e-1)" "unprognostic (1.63e-1)" "unprognostic (3.34e-1)" "unprognostic (7.83e-2)" 1.5 13.5 1.3 0.3 1.8 0.0 1.5 1.3 2.4 22.3 1.9 1.6 0.4 3.3 3.5 1.7 1.1 2.7 1.2 1.4 1.2 9.2 4.9 23.3 0.0 1.4 1.3 1.7 3.5 0.9 11.6 48.7 1.2 4.2 0.1 0.0 1.4 3.8 0.3 8.6 0.3 0.3 1.2 11.3 0.5 19.0 1.7 0.2 1.2 1.1 0.0 15.0 8.2 2.0 0.0 0.5 4.0 0.6 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 17.3 0.0 0.3 0.0 0.3 0.0 0.0 0.0 2.2 0.0 1.5 6.1 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.5 0.0 0.2 2.2 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.4 0.1 6.7 0.0 2.6 0.4 0.0 0.7 0.0 0.0 5.3 0.4 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 1.3 1.8 1.3 2.4 1.4 1.2 1.4 1.3 1.2 1.2 1.7 2.0 1.5 0.0 0.0 1.0 0.0 6.8 0.0 0.0 0.0 0.0 0.4 0.4 1.3 0.0 0.0 1.8 0.0 0.7 0.0 0.0 0.0 0.1 1.9 1.6 48.5 1.7 0.0 0.0 1.7 0.0 0.8 20.7 0.0 1.1 0.0 27.8 3.6 0.1 1.5 0.0 4.1 0.2 0.0 0.0 10.2 12.6 118.4 0.5 10.6 36.5 0.1 0.0 0.0 0.0 1.0 0.1 0.0 364.1 0.0 0.2 0.0 0.2 0.0 0.0 46.0 0.1 10.0 1.0 3.5 0.0 4.4 1.0 0.8 38.1 0.0 0.1 LANCL2 "GPR69B, TASP" ENSG00000132434 "LanC like 2" Q9NS86 7 55365337-55433737 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 52.5;Late spermatids: 55.3;Oligodendrocyte precursor cells: 52.8;Oligodendrocytes: 67.3" "Group enriched" "Detected in all" 5 "glioma: 52.5;testis cancer: 19.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in all" 8 "A-431: 144.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019711, HPA029535" Uncertain Supported Nucleoplasm,Cytosol NA NA 13000 "Cluster 39: Non-specific - mRNA processing" "Cluster 10: Brain - Neuronal signaling" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Cytosol" "HPA019711: AB_1852699, HPA029535: AB_10602342" "unprognostic (1.11e-1)" "unprognostic (6.89e-2)" "unprognostic (7.28e-2)" "unprognostic (1.28e-2)" "unprognostic (1.20e-1)" "unprognostic (1.76e-2)" "unprognostic (1.01e-1)" "unprognostic (1.31e-1)" "unprognostic (2.56e-1)" "prognostic favorable (1.89e-4)" "unprognostic (1.35e-3)" "unprognostic (5.58e-2)" "prognostic favorable (1.03e-6)" "unprognostic (4.58e-3)" "unprognostic (1.04e-2)" "unprognostic (3.94e-1)" "unprognostic (1.45e-1)" 3.9 6.2 17.4 2.6 18.8 3.9 5.9 11.5 18.6 5.7 8.7 4.9 5.1 10.4 5.1 4.1 5.4 3.8 4.1 21.2 14.2 6.0 5.0 3.1 3.5 12.5 12.9 9.1 4.7 9.2 6.0 4.0 12.4 5.8 4.7 8.4 4.7 6.4 7.0 5.5 5.0 6.7 13.2 3.6 4.4 6.2 14.2 4.7 6.5 5.1 2.9 3.9 4.0 17.4 144.8 4.9 9.7 6.6 2.9 5.0 5.4 6.4 7.6 9.7 8.2 5.0 4.1 10.1 5.9 9.3 9.7 6.4 5.2 3.5 5.9 4.4 10.4 3.6 3.8 5.1 5.1 11.2 6.4 9.0 3.7 7.2 2.3 5.1 4.8 4.7 6.4 6.4 9.1 4.4 2.9 5.2 18.8 3.9 6.1 4.3 4.5 5.0 6.3 11.3 16.9 16.0 9.3 13.6 3.9 3.6 5.6 11.8 8.1 6.1 8.3 11.6 12.5 6.1 7.8 10.6 4.8 2.5 11.8 0.1 1.5 0.3 1.0 1.9 1.7 1.1 1.3 1.5 1.9 1.0 1.2 1.0 0.2 1.5 1.4 1.5 2.6 1.1 17.4 18.8 11.5 18.6 21.2 14.2 12.5 12.9 12.4 13.2 14.2 17.4 3.0 3.2 8.9 28.7 5.9 4.0 6.3 5.5 5.7 8.9 6.8 6.7 9.4 10.0 5.1 11.0 6.2 12.5 5.1 8.8 5.9 7.1 52.5 6.7 11.2 5.4 12.6 12.6 41.7 12.2 12.1 16.3 5.1 7.7 11.4 10.2 7.1 10.0 7.7 15.2 39.6 9.1 4.1 7.3 4.8 55.3 9.0 5.4 0.0 8.4 9.5 10.8 6.2 52.8 67.3 7.8 7.6 7.5 5.1 5.5 9.8 27.7 7.7 7.6 0.0 19.4 5.9 22.7 17.8 7.5 3.8 19.0 4.3 12.8 9.7 6.0 LAS1L "FLJ12525, Las1" ENSG00000001497 "LAS1 like ribosome biogenesis factor" Q9Y4W2 X 65438549-65534810 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "rRNA processing" "Disease variant, Mental retardation, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 148.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044431, HPA061463" Supported Approved "Nucleoplasm,Centriolar satellite,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 43: Testis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "Centriolar satellite, Cytosol" "HPA044431: AB_10965695, HPA061463: AB_2684530" "unprognostic (9.71e-2)" "unprognostic (1.62e-3)" "unprognostic (1.57e-1)" "unprognostic (1.47e-1)" "unprognostic (3.39e-2)" "unprognostic (2.38e-1)" "unprognostic (7.15e-3)" "unprognostic (2.83e-2)" "unprognostic (3.16e-1)" "unprognostic (2.76e-2)" "unprognostic (2.14e-1)" "unprognostic (5.06e-2)" "unprognostic (6.00e-3)" "unprognostic (1.26e-1)" "unprognostic (1.17e-3)" "unprognostic (2.00e-3)" "unprognostic (1.53e-1)" 21.5 19.1 36.9 11.4 37.8 16.0 21.2 35.6 53.7 27.1 34.0 26.4 5.8 23.1 6.8 20.0 25.5 6.3 18.6 34.8 34.8 19.1 19.6 17.4 13.1 36.3 37.1 29.9 21.2 12.2 17.5 8.9 36.8 22.7 8.1 9.4 18.8 11.9 19.3 25.4 18.5 10.3 38.1 22.5 20.0 33.6 37.1 12.8 20.5 6.3 14.0 24.2 21.4 37.8 44.1 63.6 36.3 28.5 12.4 16.1 29.1 28.5 14.9 42.8 36.4 30.4 31.3 95.0 31.3 17.8 28.7 31.3 63.9 39.6 50.6 25.6 52.3 32.2 53.2 32.4 16.6 95.9 26.8 17.8 28.7 40.5 25.6 15.1 26.0 46.1 80.3 71.3 25.5 51.8 62.4 53.6 52.6 49.8 63.1 56.2 67.4 79.9 24.7 17.9 24.6 32.9 51.3 26.0 20.1 25.8 19.5 44.6 22.2 26.4 50.9 73.2 44.4 23.7 37.7 94.6 28.1 92.5 13.6 17.7 17.7 11.2 20.1 24.0 21.3 23.9 18.6 23.5 24.2 26.4 23.2 19.8 2.0 22.9 19.3 19.1 21.7 21.0 36.9 37.8 35.6 53.7 34.8 34.8 36.3 37.1 36.8 38.1 37.1 37.8 15.5 12.8 22.3 23.2 21.6 18.2 21.4 24.8 9.1 34.9 12.7 13.6 9.2 21.5 27.0 3.7 29.2 32.8 13.3 6.9 15.6 27.9 58.0 17.5 20.0 17.2 16.7 18.1 19.6 26.6 31.4 16.8 11.7 12.9 18.3 26.0 8.9 14.8 16.3 45.4 17.7 9.4 18.3 8.5 13.4 148.2 17.4 11.7 10.6 8.4 18.1 16.1 12.3 13.0 12.5 21.4 7.7 15.4 26.3 23.5 10.2 14.3 26.7 34.2 13.1 21.8 22.8 24.1 19.1 17.8 18.6 17.8 17.5 22.3 14.1 14.8 LCA5L "C21orf13, MGC33295" ENSG00000157578 "Lebercilin LCA5 like" O95447 21 39405728-39445805 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "testis: 110.5" "Group enriched" "Detected in many" 11 "Early spermatids: 1312.6;Late spermatids: 472.4;Spermatocytes: 465.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MCF7: 3.7;T-47d: 3.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA019790, HPA032010" Enhanced Uncertain Nucleoplasm,Cytosol NA NA "Cluster 77: Retina - Visual perception" "Cluster 6: T47d - Mammary gland" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm Cytosol "HPA019790: AB_1845690, HPA032010: AB_2674110" "unprognostic (1.02e-1)" "unprognostic (3.81e-1)" "unprognostic (2.43e-1)" "unprognostic (2.54e-3)" "unprognostic (4.69e-2)" "unprognostic (1.68e-1)" "unprognostic (3.15e-2)" "unprognostic (6.34e-2)" "unprognostic (1.27e-2)" "unprognostic (1.85e-2)" "unprognostic (5.50e-2)" "unprognostic (2.37e-1)" "unprognostic (7.53e-3)" "unprognostic (1.40e-1)" "unprognostic (1.04e-2)" "unprognostic (9.68e-3)" "unprognostic (1.95e-1)" 0.4 1.7 0.6 0.4 0.7 0.3 1.7 1.4 1.1 1.8 3.4 0.6 0.4 1.2 7.6 0.4 7.2 0.8 0.5 0.6 0.8 2.4 0.7 1.5 0.3 2.0 2.5 0.9 1.3 2.2 2.0 0.3 1.6 0.8 0.5 10.8 0.9 0.9 2.1 0.9 0.4 0.6 2.0 0.4 0.8 110.5 0.9 0.3 4.3 1.5 0.2 0.5 0.5 1.1 0.9 1.0 0.6 1.7 0.8 0.7 0.1 0.2 0.4 0.5 0.0 0.5 1.0 0.7 0.7 0.9 0.2 0.2 0.1 0.5 0.3 0.3 0.8 0.4 0.8 0.1 0.7 1.1 0.0 0.6 2.3 1.6 1.7 1.1 0.3 1.0 1.7 0.6 0.6 3.7 0.3 0.4 3.2 0.6 1.0 0.2 0.2 0.7 1.7 0.3 1.1 0.5 2.0 0.8 1.4 0.3 3.9 0.1 0.1 0.3 0.2 0.9 0.2 1.8 1.1 0.1 1.4 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.7 1.4 1.1 0.6 0.8 2.0 2.5 1.6 2.0 0.9 1.1 1.1 3.2 0.5 5.5 0.3 0.5 0.9 2.7 1.2 2.0 4.5 5.0 2.6 1.5 16.8 7.3 6.2 1.1 0.1 0.4 19.6 3.5 1312.6 34.9 2.4 1.6 4.2 0.0 3.8 2.2 0.2 2.2 0.5 2.8 0.0 1.8 1.4 1.6 0.5 1.7 2.6 1.4 0.0 0.6 0.7 472.4 6.5 1.3 1.8 1.0 0.6 3.2 0.0 0.5 2.1 1.6 0.5 7.9 0.0 0.6 0.2 12.0 68.0 17.4 19.7 3.6 1.7 465.8 26.7 0.3 0.6 0.3 0.3 3.2 0.9 0.7 LCN10 ENSG00000187922 "Lipocalin 10" Q6JVE6 9 136738167-136743356 "Predicted secreted proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 32.3" "Cell type enriched" "Detected in single" 32 "B-cells: 6.4" "Cancer enriched" "Detected in single" 8 "thyroid cancer: 1.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 18 "memory B-cell: 6.5;naive B-cell: 6.4" "Lineage enriched" "Detected in single" 18 "B-cells: 6.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA055919 Approved "Secreted in male reproductive system" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 57: B-cells - Immune response" "HPA055919: AB_2682969" "unprognostic (2.02e-1)" "unprognostic (1.35e-2)" "unprognostic (2.62e-1)" "unprognostic (1.89e-1)" "unprognostic (5.85e-2)" "unprognostic (6.54e-3)" "unprognostic (2.22e-4)" "unprognostic (4.54e-2)" "unprognostic (3.97e-1)" "unprognostic (1.31e-1)" "unprognostic (4.14e-3)" "unprognostic (2.96e-1)" "unprognostic (2.77e-2)" "unprognostic (3.11e-2)" "unprognostic (2.52e-1)" "unprognostic (8.32e-2)" "unprognostic (3.86e-1)" 3.5 0.1 1.4 1.0 1.3 0.8 2.8 1.2 2.3 6.1 1.2 1.7 0.1 7.7 32.3 1.2 7.8 0.4 8.2 1.3 1.2 0.1 0.1 0.9 1.3 1.3 1.3 2.1 1.0 0.3 0.1 0.0 1.3 2.7 0.7 0.0 1.6 1.0 0.8 0.7 2.7 3.1 1.2 1.6 2.2 1.2 1.6 0.3 2.1 2.0 1.1 3.2 2.4 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.5 0.1 0.0 0.0 0.7 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.0 6.4 0.2 0.0 0.0 0.2 0.0 0.0 0.3 0.3 1.4 1.3 1.2 2.3 1.3 1.2 1.3 1.3 1.3 1.2 1.6 1.3 0.2 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 LCN6 ENSG00000267206 "Lipocalin 6" P62502 9 136744017-136748525 "Predicted intracellular proteins, Predicted secreted proteins" Fertilization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 60 "epididymis: 1581.7" "Group enriched" "Detected in some" 4 "Adipocytes: 20.2;Endothelial cells: 80.6" "Cancer enriched" "Detected in some" 10 "thyroid cancer: 5.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "NB-4: 3.3;REH: 10.7" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 14: REH - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (4.05e-2)" "unprognostic (1.01e-3)" "unprognostic (1.12e-1)" "unprognostic (5.88e-2)" "unprognostic (3.23e-1)" "unprognostic (1.26e-1)" "unprognostic (3.83e-4)" "unprognostic (3.41e-2)" "unprognostic (7.47e-2)" "unprognostic (1.08e-2)" "unprognostic (2.89e-3)" "unprognostic (1.78e-1)" "unprognostic (5.55e-2)" "unprognostic (2.96e-2)" "unprognostic (7.19e-2)" "unprognostic (1.20e-2)" "unprognostic (1.45e-1)" 10.3 0.3 2.2 1.3 1.9 4.4 9.8 1.7 2.8 11.7 1.7 5.1 0.4 19.1 1581.7 3.3 12.7 2.0 26.3 1.8 1.9 0.9 0.3 3.4 0.9 1.9 2.1 5.6 3.1 0.9 0.5 0.0 2.0 7.6 0.8 0.0 4.5 4.3 2.8 2.2 7.6 5.3 1.8 3.2 7.3 3.9 2.7 0.4 5.2 6.5 0.4 8.3 6.3 1.9 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 10.7 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 1.9 1.7 2.8 1.8 1.9 1.9 2.1 2.0 1.8 2.7 1.9 20.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.1 3.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 80.6 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 10.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.8 5.6 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 1.4 0.0 0.0 0.0 0.1 6.6 0.1 1.6 0.4 0.5 0.0 0.0 0.0 5.3 0.0 0.0 1.5 LDHAL6A "LDH6A, MGC23940" ENSG00000166800 "Lactate dehydrogenase A like 6A" Q6ZMR3 11 18455824-18479601 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 9.8" "Cell type enhanced" "Detected in some" "Early spermatids: 13.3;Excitatory neurons: 3.5;Late spermatids: 7.4;Spermatocytes: 19.3;Spermatogonia: 3.5" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebellum: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "HL-60: 11.0" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 78: Testis - Spermatogenesis" "Cluster 32: U-937 - Innate immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (1.41e-1)" "unprognostic (4.84e-2)" "unprognostic (8.95e-2)" "unprognostic (5.35e-2)" "unprognostic (1.03e-1)" "unprognostic (3.31e-2)" "unprognostic (7.34e-2)" "unprognostic (1.75e-1)" "unprognostic (1.23e-1)" "unprognostic (1.60e-1)" "unprognostic (2.35e-2)" "unprognostic (3.58e-1)" "unprognostic (2.22e-2)" "unprognostic (2.51e-1)" "unprognostic (1.81e-1)" "unprognostic (8.31e-3)" "unprognostic (1.48e-1)" 0.1 0.5 0.2 0.3 0.3 1.0 0.1 1.6 0.4 0.0 0.0 0.1 0.6 0.2 0.2 0.2 0.1 0.2 0.1 0.2 0.1 0.1 0.0 0.1 0.4 0.2 0.0 0.3 0.3 0.0 0.1 0.2 0.3 0.1 0.1 1.1 0.2 0.2 0.1 0.9 0.5 0.0 0.0 0.3 0.3 9.8 0.1 0.1 0.5 0.0 0.2 0.0 0.0 0.2 0.1 0.3 0.7 0.5 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.2 0.3 0.6 0.1 0.0 0.1 0.3 0.0 0.2 0.3 0.5 0.5 0.4 0.7 0.3 0.0 11.0 0.5 0.1 0.2 0.0 0.1 0.1 0.0 0.7 0.3 0.7 0.0 0.2 0.3 0.8 0.2 0.1 0.4 0.5 0.3 0.2 0.1 0.7 0.3 0.3 0.3 0.2 0.1 0.3 0.2 1.5 0.5 0.4 0.1 0.6 0.2 0.2 0.2 0.1 0.2 0.4 0.2 0.6 0.0 0.1 0.4 0.0 0.0 0.2 0.0 0.1 0.1 0.2 0.2 0.2 0.7 0.3 0.1 0.0 0.3 0.1 0.2 0.3 1.6 0.4 0.2 0.1 0.2 0.0 0.3 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 13.3 0.1 0.1 0.1 0.0 0.0 3.5 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 7.4 0.9 0.1 0.0 0.0 0.0 0.9 1.0 1.5 0.9 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.8 0.0 0.2 0.0 19.3 3.5 0.0 0.0 0.3 0.0 0.3 0.0 0.0 LDLR LDLCQ2 ENSG00000130164 "Low density lipoprotein receptor" P01130 19 11089462-11133820 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol metabolism, Endocytosis, Host-virus interaction, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" "Host cell receptor for virus entry, Receptor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 112.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 397.4;Alveolar cells type 2: 468.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 9 "basophil: 46.0" "Lineage enriched" "Detected in many" 9 "granulocytes: 46.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009647, HPA013159" Approved NA NA 23000000 "Cluster 38: Basophils - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 44: Endometrium - Transcription" "HPA009647: AB_1079243, HPA013159: AB_1852775" "unprognostic (4.39e-1)" "unprognostic (1.93e-3)" "unprognostic (2.52e-1)" "unprognostic (2.76e-1)" "unprognostic (4.03e-2)" "unprognostic (1.17e-1)" "unprognostic (6.71e-2)" "unprognostic (4.26e-2)" "unprognostic (3.73e-1)" "unprognostic (1.47e-2)" "prognostic unfavorable (6.60e-5)" "unprognostic (1.19e-1)" "prognostic unfavorable (5.92e-4)" "unprognostic (1.62e-1)" "unprognostic (2.78e-2)" "unprognostic (9.83e-2)" "prognostic unfavorable (3.43e-4)" 43.6 112.1 6.4 27.3 7.5 27.4 15.6 8.6 13.0 27.5 22.0 20.0 23.6 21.6 3.8 50.1 21.6 36.9 19.3 8.4 10.8 15.2 60.4 54.8 4.8 24.3 14.4 37.7 50.7 10.1 6.9 16.6 20.0 20.2 12.2 2.3 19.1 4.6 3.9 25.5 18.3 28.6 9.9 10.5 36.5 8.4 11.7 4.0 7.7 4.0 5.1 22.6 25.8 14.5 113.6 52.2 61.1 29.9 80.5 152.7 21.0 23.5 89.8 41.3 88.6 52.9 105.3 37.2 94.1 46.1 135.6 88.3 31.1 185.6 19.9 27.5 6.1 18.1 34.5 47.1 120.2 19.2 100.9 192.5 67.5 139.6 30.2 28.5 45.8 29.5 38.9 213.8 31.9 41.4 25.3 25.9 66.4 56.0 67.5 17.1 44.9 48.2 103.1 89.5 14.8 15.4 21.1 45.7 3.8 45.2 19.0 44.6 50.8 36.1 26.3 23.2 44.7 26.8 24.4 23.3 42.8 43.7 83.6 46.0 2.9 0.1 5.4 2.6 1.3 0.6 2.2 1.7 1.6 0.5 2.3 2.2 0.8 2.5 0.8 0.5 1.6 3.2 6.4 7.5 8.6 13.0 8.4 10.8 24.3 14.4 20.0 9.9 11.7 14.5 106.3 397.4 468.6 16.3 8.1 143.4 176.8 182.2 85.4 11.4 144.0 108.7 35.9 92.9 205.7 14.7 6.2 18.4 24.7 273.7 1.9 57.9 1.2 95.3 61.7 75.8 61.9 6.6 10.7 89.0 32.1 42.9 195.2 278.6 75.9 32.9 22.9 149.2 14.9 1.7 8.1 157.2 77.3 16.5 26.5 1.6 19.6 47.4 56.9 7.5 2.7 6.8 8.2 7.5 19.4 86.7 209.7 7.2 30.7 142.7 32.5 0.6 99.1 6.6 6.6 133.4 48.4 4.1 2.8 155.3 197.2 48.2 32.8 214.3 110.7 184.2 LEF1 "TCF10, TCF1ALPHA, TCF7L3" ENSG00000138795 "Lymphoid enhancer binding factor 1" Q9UJU2 4 108047545-108168956 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Wnt signaling pathway" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 19 "lymphoid tissue: 349.2" "Cell type enhanced" "Detected in many" "Melanocytes: 33.8;Microglial cells: 145.2;T-cells: 70.3" "Cancer enhanced" "Detected in all" "melanoma: 25.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 142.6" "Lineage enriched" "Detected in many" 4 "T-cells: 142.6" "Group enriched" "Detected in many" 5 "JURKAT: 579.6;MOLT-4: 569.0;REH: 454.8" "Region enhanced" "Detected in all" "thalamus: 22.6" "Low region specificity" "Detected in all" "HPA002087, CAB019405" Enhanced Approved Nucleoplasm NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" Nucleoplasm "CAB019405: AB_823558, HPA002087: AB_1079245" "unprognostic (1.03e-3)" "unprognostic (7.36e-3)" "unprognostic (2.97e-2)" "prognostic favorable (1.37e-5)" "unprognostic (9.08e-2)" "unprognostic (5.24e-2)" "unprognostic (3.81e-2)" "unprognostic (1.10e-2)" "unprognostic (1.77e-1)" "unprognostic (5.21e-2)" "unprognostic (9.99e-2)" "unprognostic (1.37e-1)" "prognostic unfavorable (2.47e-6)" "unprognostic (1.12e-1)" "unprognostic (5.22e-2)" "unprognostic (7.88e-2)" "unprognostic (8.91e-2)" 1.0 12.7 10.7 13.8 7.6 11.6 2.0 6.1 7.9 4.2 14.3 1.5 0.7 8.0 4.8 3.2 5.1 3.9 0.2 5.7 9.9 2.5 0.3 3.3 31.3 8.9 11.2 1.1 0.1 0.3 1.0 11.0 9.4 3.7 1.4 0.5 1.0 1.0 0.1 2.8 4.1 3.9 5.9 9.8 1.5 12.3 18.2 349.2 3.0 0.1 22.8 5.5 3.0 5.5 0.1 0.0 8.0 0.0 0.0 0.0 0.0 0.2 7.2 1.8 4.7 27.1 0.0 0.0 0.1 0.0 2.5 0.2 7.9 0.0 3.7 0.3 17.6 6.9 0.0 0.0 0.0 23.6 2.9 0.4 0.4 0.0 0.7 3.5 0.0 579.6 14.2 0.0 2.6 1.0 569.0 0.0 1.7 6.3 1.4 454.8 9.1 0.2 2.4 1.3 3.0 5.2 0.0 0.5 83.8 6.7 2.4 0.2 0.0 11.9 10.3 0.0 15.3 38.3 17.0 100.9 7.8 0.0 48.4 0.3 0.2 0.0 8.2 0.0 1.6 0.6 68.3 29.9 0.1 0.9 142.6 102.2 1.9 32.9 0.3 0.5 97.7 36.8 10.7 7.6 6.1 7.9 5.7 9.9 8.9 11.2 9.4 5.9 18.2 5.5 1.4 3.2 1.9 2.0 4.4 3.3 1.4 1.0 24.5 0.1 0.4 5.0 1.6 0.0 0.7 0.0 0.0 0.1 6.2 0.0 13.7 0.0 4.2 5.8 22.3 22.0 0.0 9.2 0.2 0.0 0.2 2.1 0.0 4.5 0.0 0.0 0.0 0.0 0.3 0.0 1.2 0.2 4.1 0.3 1.4 7.9 0.6 2.0 33.8 145.2 3.5 0.6 10.3 0.5 0.6 0.1 0.0 0.0 5.4 1.8 0.0 0.5 2.3 0.3 0.0 0.6 9.0 16.1 6.6 11.3 1.3 0.4 70.3 0.0 0.9 0.4 LEKR1 FLJ16641 ENSG00000197980 "Leucine, glutamate and lysine rich 1" 3 156825481-157046129 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "testis: 12.8" "Cell type enhanced" "Detected in many" "Early spermatids: 96.8;Late spermatids: 47.7;Respiratory ciliated cells: 28.0;Spermatocytes: 65.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 3.3;U-266/70: 2.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044039, HPA047774" Uncertain Approved Nucleoplasm,Nucleoli NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 29: U-266 - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm Nucleoli "HPA044039: AB_10794288, HPA047774: " "unprognostic (5.42e-2)" "unprognostic (1.17e-1)" "unprognostic (3.22e-2)" "unprognostic (8.64e-2)" "unprognostic (1.67e-1)" "unprognostic (1.94e-1)" "unprognostic (2.29e-3)" "unprognostic (1.98e-2)" "unprognostic (7.55e-2)" "unprognostic (2.20e-1)" "unprognostic (5.66e-3)" "unprognostic (3.50e-2)" "unprognostic (5.99e-2)" "unprognostic (6.59e-2)" "unprognostic (3.28e-1)" "unprognostic (2.17e-3)" "unprognostic (1.80e-2)" 0.9 1.0 0.7 0.3 1.0 0.2 1.6 0.9 0.7 0.5 1.9 0.6 1.0 0.7 3.4 0.3 3.8 0.4 0.9 0.9 1.1 1.4 0.7 0.6 1.0 1.9 1.7 0.9 1.0 1.5 1.5 0.2 1.5 0.9 0.6 1.8 0.6 0.6 0.2 0.4 0.6 0.4 1.6 0.5 0.9 12.8 1.1 0.7 2.3 0.2 0.4 0.5 0.2 1.0 3.3 1.2 0.0 0.7 0.4 0.2 0.1 0.1 0.5 0.6 0.5 0.1 1.7 0.0 0.9 0.4 1.2 1.2 0.0 0.3 1.3 0.5 0.3 1.0 0.1 0.0 0.0 1.0 0.2 1.5 0.8 0.1 0.9 0.3 0.3 0.0 0.7 0.6 1.2 1.2 0.0 0.7 1.0 0.9 0.7 0.0 0.8 0.8 1.0 0.2 1.9 0.7 1.0 0.7 0.0 0.2 2.2 1.8 0.0 0.1 0.3 0.2 0.5 2.9 0.5 0.0 0.5 0.7 1.0 0.6 0.0 0.0 0.2 0.0 0.4 0.8 0.4 0.0 0.3 0.9 0.4 0.2 0.0 0.7 0.0 0.5 0.6 0.1 0.7 1.0 0.9 0.7 0.9 1.1 1.9 1.7 1.5 1.6 1.1 1.0 0.5 0.0 1.1 19.9 6.3 1.3 1.1 1.4 2.8 1.2 2.7 3.9 1.5 1.5 2.8 3.7 2.1 0.3 0.7 1.5 3.9 0.7 96.8 20.7 1.4 0.6 0.0 2.1 6.5 1.6 0.1 1.1 9.7 2.8 1.3 1.4 0.0 1.8 0.2 3.3 11.8 0.9 0.0 1.6 1.3 47.7 1.5 1.8 1.8 3.7 1.1 1.7 0.0 8.0 8.0 1.0 0.6 1.9 2.5 0.7 1.2 5.4 28.0 4.8 0.0 0.6 1.4 65.2 4.3 2.2 0.9 0.1 2.3 1.1 0.9 0.8 LETM1 SLC55A1 ENSG00000168924 "Leucine zipper and EF-hand containing transmembrane protein 1" O95202 4 1811479-1856156 "Human disease related genes, Predicted membrane proteins, Transporters" "Antiport, Calcium transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 116.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011029, HPA011100" Supported Supported Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA011029: AB_1852804, HPA011100: AB_1852802" "unprognostic (1.16e-1)" "unprognostic (1.80e-1)" "unprognostic (3.85e-2)" "unprognostic (5.04e-2)" "unprognostic (5.48e-1)" "unprognostic (1.17e-1)" "prognostic unfavorable (1.79e-4)" "unprognostic (1.37e-3)" "unprognostic (1.87e-1)" "unprognostic (3.29e-1)" "unprognostic (1.80e-1)" "prognostic unfavorable (1.77e-4)" "prognostic favorable (8.90e-4)" "unprognostic (8.06e-3)" "unprognostic (3.24e-1)" "unprognostic (1.57e-2)" "unprognostic (2.42e-1)" 13.6 16.3 14.3 7.9 13.7 7.7 10.8 11.7 14.6 8.2 10.8 20.3 13.9 8.4 3.2 23.8 8.0 4.5 19.6 13.4 13.2 13.3 16.4 8.9 7.0 12.7 13.5 9.2 12.5 11.4 8.8 4.9 11.9 8.4 10.7 4.5 9.6 4.2 18.7 15.9 11.7 5.1 12.2 10.7 13.8 14.5 15.0 25.7 10.7 10.9 7.9 8.4 10.6 11.6 22.9 38.1 11.6 36.1 17.4 12.2 20.7 22.1 10.7 21.8 16.9 35.5 24.7 37.5 15.4 23.3 34.0 22.7 29.8 31.2 13.2 25.1 31.1 38.4 30.9 25.6 22.6 39.3 30.3 19.9 22.0 24.9 21.8 10.1 19.0 22.6 51.5 22.9 15.3 25.1 57.3 44.7 30.5 24.7 43.2 32.4 16.2 21.9 17.0 31.3 29.5 26.0 25.2 31.5 13.3 10.0 29.7 20.3 28.8 24.8 14.8 21.1 37.3 19.8 32.7 29.3 22.0 33.8 20.2 3.9 3.7 2.0 5.8 5.0 5.7 4.2 4.9 4.9 4.1 3.6 3.2 4.6 0.5 5.9 5.1 12.9 4.2 2.1 14.3 13.7 11.7 14.6 13.4 13.2 12.7 13.5 11.9 12.2 15.0 11.6 12.2 16.0 11.5 15.0 19.2 40.0 40.7 13.4 8.0 19.4 19.7 10.5 23.3 11.5 14.0 27.6 33.3 17.5 24.9 116.1 31.3 25.5 32.2 9.1 19.4 16.7 15.6 20.4 14.3 31.3 22.6 17.0 32.1 14.7 10.2 17.9 16.1 33.3 21.5 15.2 12.4 29.5 12.2 18.4 19.8 45.1 20.2 13.0 19.6 4.7 13.9 12.7 28.8 9.5 13.2 42.4 52.7 16.6 17.8 58.8 48.8 46.1 5.6 28.4 13.1 23.8 16.1 54.2 44.4 25.2 51.1 15.2 16.7 21.9 53.2 48.4 LGALS13 "PLAC8, PP13" ENSG00000105198 "Galectin 13" Q9UHV8 19 39602501-39607474 "Metabolic proteins, Predicted intracellular proteins" Apoptosis Hemagglutinin "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 16 "placenta: 11.8" "Cell type enriched" "Detected in some" 17 "Syncytiotrophoblasts: 319.9" "Cancer enriched" "Detected in single" 4 "thyroid cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 22 "SuSa: 2.1" HPA046803 Supported Nucleoplasm NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 12: NES - Nervous system development" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm "HPA046803: AB_10965990" 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 11.8 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.6 0.1 0.7 0.2 0.5 0.3 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 17.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 319.9 0.0 0.0 0.0 0.0 LGR4 GPR48 ENSG00000205213 "Leucine rich repeat containing G protein-coupled receptor 4" Q9BXB1 11 27365961-27472790 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Biological rhythms, Differentiation, Immunity, Innate immunity, Spermatogenesis, Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 204.4;Distal enterocytes: 123.3;Glandular and luminal cells: 137.7;Syncytiotrophoblasts: 128.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HAP1: 83.5;RPTEC TERT1: 100.4;U-2197: 82.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030267, HPA054350" Uncertain Approved "Centriolar satellite" NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" "Centriolar satellite" "HPA030267: AB_10610004, HPA054350: " "unprognostic (5.27e-3)" "unprognostic (5.18e-2)" "unprognostic (4.64e-3)" "unprognostic (1.59e-1)" "unprognostic (4.92e-2)" "unprognostic (2.31e-1)" "unprognostic (1.98e-1)" "unprognostic (2.02e-2)" "unprognostic (2.00e-2)" "unprognostic (4.63e-2)" "unprognostic (5.84e-3)" "unprognostic (2.10e-1)" "prognostic favorable (2.00e-7)" "unprognostic (5.01e-1)" "unprognostic (3.59e-1)" "unprognostic (3.54e-2)" "unprognostic (1.76e-1)" 16.4 16.8 10.2 8.1 10.2 2.4 16.1 13.0 9.2 7.5 10.2 36.8 22.6 10.2 13.3 13.7 10.2 9.0 19.4 7.8 10.5 51.5 55.7 3.2 1.5 14.1 10.4 22.9 59.7 6.4 6.8 34.4 12.8 15.4 36.8 44.4 18.1 16.1 14.4 18.3 24.7 13.2 13.4 11.7 31.0 13.9 10.1 4.4 15.2 8.2 3.0 10.1 11.7 18.0 28.3 50.7 49.5 5.7 4.5 3.1 56.0 15.7 14.8 13.8 11.8 7.6 0.5 0.1 10.1 21.2 23.2 45.8 83.5 31.1 23.5 0.2 37.0 15.3 28.4 36.1 1.4 1.6 0.1 4.1 19.5 9.5 21.0 57.0 7.0 0.0 4.5 0.1 5.7 9.0 0.1 2.7 47.9 76.3 20.4 0.2 33.8 3.3 100.4 12.1 0.7 6.0 7.7 45.7 4.6 37.6 15.1 23.4 22.6 10.2 8.2 82.6 14.6 18.9 15.2 0.0 17.3 0.0 6.4 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.2 10.2 13.0 9.2 7.8 10.5 14.1 10.4 12.8 13.4 10.1 18.0 1.7 3.2 0.5 204.4 1.4 30.3 13.5 33.1 38.7 18.6 17.2 14.1 26.6 24.3 15.4 44.1 25.0 55.1 0.4 123.3 3.9 21.4 7.1 75.4 11.5 3.9 16.8 3.4 35.6 50.7 29.2 14.5 43.3 137.7 0.0 78.6 3.6 60.7 8.1 25.2 51.6 47.1 20.3 5.3 5.7 2.2 5.0 1.6 7.2 15.0 2.1 109.8 0.0 36.7 62.1 31.4 48.8 17.0 0.6 11.7 37.9 19.4 14.5 14.8 6.6 6.9 13.0 1.3 1.4 36.8 21.9 128.6 1.8 6.3 55.5 19.7 LIAS LAS ENSG00000121897 "Lipoic acid synthetase" O43766 4 39459004-39485109 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 86.0;Late spermatids: 100.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018842, HPA019076" Approved Supported Approved Nucleoplasm,Mitochondria Yes No "Cluster 30: Non-specific - Translation" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Mitochondria "HPA018842: AB_1852864, HPA019076: AB_1852866" "unprognostic (3.61e-1)" "unprognostic (1.89e-1)" "unprognostic (8.44e-2)" "unprognostic (2.33e-1)" "unprognostic (4.87e-2)" "unprognostic (1.49e-1)" "unprognostic (8.31e-2)" "unprognostic (1.57e-1)" "unprognostic (4.19e-2)" "unprognostic (3.68e-2)" "unprognostic (2.46e-3)" "unprognostic (3.80e-2)" "prognostic favorable (4.11e-7)" "unprognostic (9.41e-3)" "unprognostic (2.35e-1)" "unprognostic (5.45e-2)" "unprognostic (6.98e-2)" 5.4 7.5 5.9 3.0 6.5 6.6 5.7 7.6 9.8 5.1 5.9 6.4 5.5 4.6 5.3 6.7 6.1 3.6 11.1 6.2 6.7 8.7 8.6 2.9 5.1 6.3 6.4 10.0 6.8 6.5 4.0 3.3 6.8 4.1 6.4 5.4 4.3 3.1 27.2 5.7 5.2 5.2 5.5 3.6 6.3 9.8 6.2 4.3 4.2 21.0 4.2 5.8 4.7 8.3 5.7 4.5 5.4 5.2 11.5 11.4 4.8 6.6 3.7 6.1 4.1 6.8 7.8 20.8 7.3 2.5 15.2 4.9 15.9 9.1 8.0 2.4 4.0 8.8 2.3 7.0 10.4 19.1 5.5 10.8 14.6 7.1 22.4 13.4 7.0 12.7 21.1 5.2 7.5 3.6 10.9 24.9 7.3 15.3 14.2 9.1 15.2 12.9 7.1 2.9 6.0 4.8 3.8 4.9 22.5 7.6 5.6 8.8 2.6 4.7 10.6 6.3 15.5 9.9 15.8 14.3 7.2 22.2 4.0 2.5 6.4 3.9 5.7 7.6 12.7 10.0 8.1 8.0 6.2 7.6 16.2 11.6 3.4 7.7 5.6 5.5 5.7 4.7 5.9 6.5 7.6 9.8 6.2 6.7 6.3 6.4 6.8 5.5 6.2 8.3 11.0 9.6 12.6 14.0 12.9 9.7 11.6 17.4 12.0 25.8 15.7 17.3 20.1 17.2 12.7 18.4 10.4 24.0 22.6 12.9 21.5 13.2 86.0 11.2 15.8 10.3 18.1 12.4 11.9 6.4 18.2 10.4 9.2 10.3 17.7 19.0 11.4 19.0 17.5 10.1 18.8 13.5 18.3 13.5 7.8 100.1 10.2 11.4 1.8 6.5 17.6 15.4 16.5 14.6 22.9 10.3 10.1 12.4 5.8 6.6 18.3 32.6 14.1 26.7 0.0 10.8 20.5 64.9 25.1 13.7 9.2 9.6 14.2 19.0 18.4 8.8 LILRB4 "CD85k, HM18, ILT3, LIR-5, LIR5" ENSG00000186818 "Leukocyte immunoglobulin like receptor B4" Q8NHJ6 19 54643889-54670359 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 13.7;lymphoid tissue: 18.8" "Cell type enhanced" "Detected in some" "dendritic cells: 76.9;Hofbauer cells: 127.6;Kupffer cells: 118.9;Macrophages: 104.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 37.3" "Group enriched" "Detected in many" 44 "dendritic cells: 37.3;monocytes: 10.8" "Cell line enriched" "Detected in some" 32 "Karpas-707: 407.8" HPA052807 Approved NA NA 11000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" "HPA052807: AB_2681958" "unprognostic (4.09e-2)" "unprognostic (5.75e-3)" "unprognostic (6.06e-2)" "unprognostic (1.91e-2)" "unprognostic (1.82e-1)" "unprognostic (1.55e-1)" "unprognostic (5.03e-2)" "unprognostic (3.53e-1)" "unprognostic (4.13e-2)" "unprognostic (1.52e-1)" "unprognostic (5.43e-1)" "unprognostic (2.79e-1)" "unprognostic (1.91e-2)" "unprognostic (1.08e-1)" "unprognostic (4.42e-2)" "unprognostic (4.51e-2)" "unprognostic (4.52e-2)" 8.6 4.6 2.2 10.9 2.5 2.0 3.6 2.7 4.2 1.1 2.2 4.1 1.6 0.9 0.3 1.0 4.0 1.7 2.3 2.2 2.8 2.2 2.9 13.7 11.4 3.8 3.2 0.7 1.6 0.1 2.2 1.4 3.5 1.9 2.3 0.1 3.6 0.3 0.5 0.5 6.3 0.7 3.2 18.8 1.7 0.3 3.0 0.6 2.4 0.0 2.1 6.1 0.8 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 407.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 1.4 12.8 0.0 0.2 0.0 0.4 0.0 7.8 0.0 0.0 10.8 0.0 0.2 0.0 0.0 11.7 0.5 0.0 0.0 0.1 0.1 8.9 37.3 0.0 3.8 2.2 2.5 2.7 4.2 2.2 2.8 3.8 3.2 3.5 3.2 3.0 3.3 0.6 0.0 4.1 0.0 13.4 0.4 0.0 0.0 0.0 0.2 0.3 1.7 1.0 1.5 1.3 0.0 0.0 0.3 76.9 0.1 0.0 0.0 0.2 0.0 0.0 4.2 0.0 7.8 0.1 0.0 0.9 0.5 0.0 0.0 1.3 0.0 2.2 0.8 127.6 0.0 0.2 0.0 0.0 118.9 12.6 0.6 0.0 104.0 1.8 14.0 29.3 0.2 1.0 0.0 0.0 0.1 0.0 0.0 24.3 0.0 0.0 0.0 0.0 0.2 6.6 0.2 0.1 0.0 0.4 0.1 0.1 0.8 2.2 0.0 0.2 0.1 LILRB5 "CD85c, LIR-8, LIR8" ENSG00000105609 "Leukocyte immunoglobulin like receptor B5" O75023 19 54249421-54257301 "CD markers, Plasma proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 17.9;lymphoid tissue: 49.1" "Group enriched" "Detected in some" 6 "Hofbauer cells: 61.1;Kupffer cells: 103.4;Macrophages: 40.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA012069 Approved NA NA 58000000 "Cluster 17: Basophils - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 4: Macrophages - Innate immune response" "HPA012069: AB_1852873" "unprognostic (3.55e-3)" "unprognostic (5.38e-2)" "unprognostic (2.20e-2)" "unprognostic (7.03e-2)" "unprognostic (8.86e-2)" "unprognostic (5.44e-2)" "unprognostic (3.02e-5)" "unprognostic (6.80e-2)" "unprognostic (2.23e-1)" "unprognostic (2.33e-1)" "unprognostic (9.95e-2)" "unprognostic (8.68e-2)" "unprognostic (3.31e-1)" "unprognostic (2.07e-1)" "unprognostic (4.14e-2)" "unprognostic (1.42e-2)" "unprognostic (1.73e-1)" 17.9 10.3 0.2 1.7 0.5 0.9 7.2 0.3 1.0 1.6 1.3 6.1 4.6 1.1 0.8 1.8 4.4 2.8 5.1 0.2 0.2 1.6 7.1 5.3 1.8 0.5 0.3 1.3 0.8 0.3 0.7 4.8 0.4 0.6 4.8 0.1 2.9 0.6 1.8 2.3 6.8 2.4 0.2 49.1 2.5 1.1 1.0 1.0 1.4 1.3 0.7 4.2 1.2 1.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.2 0.5 0.3 1.0 0.2 0.2 0.5 0.3 0.4 0.2 1.0 1.1 0.5 0.0 1.1 0.0 0.4 1.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 1.5 0.0 0.0 0.0 0.4 1.5 0.0 0.0 0.0 1.7 0.0 0.1 0.2 0.0 2.7 0.0 0.0 0.4 0.7 0.0 0.1 0.0 0.1 8.6 0.9 61.1 0.0 0.0 0.0 0.0 103.4 9.8 1.8 0.0 40.1 1.8 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.5 0.0 0.1 0.3 1.1 0.8 0.4 0.5 0.0 0.0 LIMK1 LIMK ENSG00000106683 "LIM domain kinase 1" P53667 7 74082933-74122525 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 77.9" "Cell type enhanced" "Detected in many" "Granulosa cells: 27.6;Horizontal cells: 35.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-87 MG: 136.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028516, HPA073571" Approved Supported "Nuclear speckles,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 70: Brain - Nervous system development" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 4: Macrophages - Innate immune response" "Nuclear speckles, Cytosol" "HPA028516: AB_10601751, HPA073571: " "unprognostic (1.45e-2)" "unprognostic (2.75e-1)" "prognostic unfavorable (4.95e-5)" "unprognostic (2.77e-2)" "unprognostic (1.40e-3)" "unprognostic (3.35e-2)" "prognostic unfavorable (7.79e-6)" "unprognostic (1.90e-2)" "unprognostic (2.16e-1)" "unprognostic (1.18e-1)" "unprognostic (3.32e-2)" "unprognostic (3.16e-2)" "prognostic unfavorable (6.63e-8)" "unprognostic (4.14e-2)" "unprognostic (7.00e-2)" "unprognostic (3.84e-2)" "unprognostic (5.79e-2)" 11.1 10.5 31.1 18.7 32.7 6.8 9.4 28.3 77.9 21.4 0.2 8.9 6.6 13.1 3.5 11.3 7.3 10.1 9.4 35.0 43.8 10.8 4.6 13.2 23.5 75.5 40.0 13.2 11.4 5.8 13.9 7.3 73.0 12.3 4.1 4.0 17.9 8.2 23.7 11.4 12.1 7.1 31.8 22.3 9.2 15.6 59.1 8.1 11.2 7.8 18.2 13.1 14.7 38.3 47.4 37.2 27.2 45.4 35.1 47.0 20.0 28.8 27.3 22.6 25.4 21.3 45.6 30.2 12.7 35.5 76.9 28.1 10.1 17.8 8.6 53.7 18.6 23.2 13.1 24.6 40.5 17.2 81.4 46.8 15.6 18.5 9.6 68.3 34.4 20.9 15.1 9.0 28.8 41.4 14.8 31.4 52.1 16.6 23.7 21.1 43.3 18.2 26.5 10.1 10.7 25.2 18.6 43.7 23.5 29.7 13.9 15.4 41.1 36.0 33.7 94.5 47.7 10.2 12.5 54.9 136.5 12.4 25.2 0.1 6.1 3.5 1.8 6.0 1.4 3.4 0.4 1.2 7.0 1.7 0.1 0.5 0.5 5.8 3.8 0.7 0.3 3.3 31.1 32.7 28.3 77.9 35.0 43.8 75.5 40.0 73.0 31.8 59.1 38.3 2.9 3.2 2.7 7.5 14.4 2.9 5.2 6.6 1.8 6.6 7.7 6.9 3.4 7.2 3.8 1.8 2.1 2.5 11.9 2.9 0.0 6.6 1.2 2.7 9.7 4.1 2.4 0.4 15.4 6.5 6.3 9.2 3.1 5.1 5.7 27.6 3.3 2.1 25.0 35.3 20.8 2.7 0.0 13.5 10.8 2.2 7.2 15.6 3.6 6.5 14.9 3.5 22.6 6.6 2.4 13.5 2.3 6.0 10.0 9.0 0.3 2.8 3.1 3.3 0.0 5.3 4.5 3.4 11.5 1.8 3.1 3.7 11.1 6.9 2.4 7.2 LIMK2 ENSG00000182541 "LIM domain kinase 2" P53671 22 31212239-31280080 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 115.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "eosinophil: 40.0;neutrophil: 96.9" "Lineage enriched" "Detected in all" 6 "granulocytes: 96.9" "Cell line enhanced" "Detected in all" "BEWO: 135.5;hTCEpi: 251.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008183, CAB019313, HPA053882" Approved Supported Nucleoplasm,Cytosol NA Yes "Cluster 5: Granulocytes - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Cytosol "CAB019313: , HPA008183: AB_1079252, HPA053882: AB_2682291" "unprognostic (1.79e-1)" "unprognostic (1.95e-1)" "unprognostic (1.04e-2)" "unprognostic (2.59e-2)" "unprognostic (1.39e-1)" "unprognostic (2.42e-2)" "unprognostic (4.02e-2)" "unprognostic (5.99e-2)" "unprognostic (1.21e-1)" "unprognostic (2.95e-1)" "unprognostic (3.96e-1)" "unprognostic (1.43e-1)" "prognostic unfavorable (4.57e-6)" "unprognostic (4.48e-2)" "unprognostic (1.48e-2)" "unprognostic (5.72e-2)" "unprognostic (1.37e-1)" 20.1 14.4 25.5 39.8 27.3 53.8 30.9 25.8 22.1 26.4 32.6 34.0 21.2 17.0 7.7 71.8 34.2 21.3 14.3 20.8 27.7 27.7 33.0 46.8 23.2 37.8 34.2 21.6 28.8 27.0 21.9 48.0 32.8 36.7 34.7 25.5 50.7 19.1 18.8 71.5 29.3 15.9 32.7 37.5 30.0 19.2 33.6 21.3 42.0 9.2 17.8 25.7 45.3 33.1 26.6 4.4 17.9 10.0 7.6 8.8 135.5 17.2 8.0 16.9 14.2 22.7 12.2 25.8 29.9 26.0 8.1 52.6 20.9 90.3 10.6 19.1 22.8 18.8 21.1 24.7 11.4 35.1 33.1 14.3 251.5 13.7 41.0 114.5 43.6 20.6 10.7 18.2 23.3 20.9 21.5 12.0 16.7 68.3 6.7 28.1 30.0 14.3 19.6 62.3 22.8 20.4 13.0 82.1 35.1 54.8 68.7 13.9 26.6 15.1 23.5 8.3 16.3 10.0 16.2 22.4 9.6 16.4 6.6 5.8 5.1 40.0 3.1 3.5 5.9 2.0 5.7 4.3 1.9 2.4 5.6 4.4 96.9 6.7 1.4 4.4 15.2 4.4 25.5 27.3 25.8 22.1 20.8 27.7 37.8 34.2 32.8 32.7 33.6 33.1 19.5 32.1 17.9 16.3 5.2 35.9 37.7 24.8 59.2 9.4 18.0 23.2 25.1 10.0 32.6 5.5 20.9 69.8 15.3 39.3 3.9 13.0 1.4 49.6 19.2 22.4 13.2 10.3 6.4 45.0 52.4 7.6 48.9 41.6 23.5 8.6 14.3 7.1 18.2 3.3 11.3 42.8 18.3 8.9 8.2 1.6 4.4 13.8 3.6 16.9 5.4 16.6 2.1 2.5 15.5 25.9 21.2 4.5 6.2 27.1 12.0 10.5 36.3 22.8 19.7 7.5 17.2 15.6 18.4 46.1 39.1 115.5 9.3 7.1 51.7 29.9 LIMS2 "PINCH-2, PINCH2" ENSG00000072163 "LIM zinc finger domain containing 2" Q7Z4I7 2 127638381-127681786 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 510.1" "Cell type enhanced" "Detected in many" "Adipocytes: 109.4;Cardiomyocytes: 91.7;Endothelial cells: 105.1;Granulosa cells: 134.1;Hepatic stellate cells: 134.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 22.5" "Group enriched" "Detected in many" 13 "B-cells: 22.5;T-cells: 10.7" "Cell line enhanced" "Detected in many" "BJ hTERT+: 27.0;fHDF/TERT166: 31.2;HHSteC: 32.7;MOLT-4: 40.2;TIME: 83.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058340 Enhanced Supported "Focal adhesion sites" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Focal adhesion sites" "HPA058340: AB_2683683" "unprognostic (2.51e-2)" "unprognostic (1.25e-1)" "unprognostic (5.82e-3)" "unprognostic (4.51e-2)" "unprognostic (9.25e-2)" "unprognostic (3.49e-1)" "prognostic favorable (6.53e-7)" "unprognostic (3.98e-2)" "unprognostic (3.73e-1)" "unprognostic (2.29e-1)" "unprognostic (3.78e-2)" "unprognostic (8.86e-2)" "unprognostic (3.33e-1)" "unprognostic (4.60e-3)" "unprognostic (3.64e-2)" "unprognostic (1.77e-1)" "unprognostic (4.00e-2)" 104.6 21.6 29.4 17.9 27.9 0.4 93.9 24.9 32.3 104.4 25.1 510.1 15.8 261.4 16.9 42.1 139.5 25.7 266.4 25.6 24.1 72.7 46.6 114.3 12.9 28.7 27.2 29.0 14.1 6.4 15.6 27.7 29.3 132.1 15.2 0.6 27.1 98.8 33.4 32.8 95.7 81.9 24.3 121.8 123.1 12.0 32.2 13.1 51.6 26.8 5.4 220.5 85.1 24.0 0.8 1.6 0.5 0.0 4.6 1.0 0.3 19.1 27.0 20.2 18.1 4.7 0.1 0.1 10.3 31.2 1.1 0.1 0.3 0.0 4.2 0.0 0.8 0.0 11.9 3.6 32.7 0.0 0.0 0.2 0.0 7.0 0.2 10.7 12.9 15.3 0.0 0.0 10.0 0.0 40.2 1.0 1.3 0.0 2.4 9.0 1.7 1.0 1.3 0.0 0.1 0.2 3.0 1.7 0.7 6.7 0.7 0.0 83.7 0.1 12.9 15.2 0.1 0.0 0.0 0.2 0.0 1.6 0.0 0.0 0.2 0.0 0.1 0.3 0.0 15.2 5.3 1.1 0.2 22.5 10.7 4.4 0.3 0.0 0.2 1.2 8.0 2.5 29.4 27.9 24.9 32.3 25.6 24.1 28.7 27.2 29.3 24.3 32.2 24.0 109.4 22.4 6.1 0.3 10.1 9.4 0.3 0.2 1.2 0.2 1.9 17.1 91.7 4.3 1.3 0.0 0.0 0.6 0.8 0.1 0.0 1.2 1.3 2.9 5.3 105.1 0.0 5.7 0.4 0.2 12.4 22.5 1.1 0.9 2.5 134.1 134.6 16.3 1.0 0.0 0.3 0.0 0.0 6.5 13.0 3.1 19.9 1.7 10.6 30.9 0.0 0.3 0.0 4.0 0.3 0.5 0.0 49.7 1.7 0.3 0.0 0.5 0.8 0.9 26.3 4.2 35.4 0.8 2.1 0.6 6.7 1.0 2.3 1.8 0.0 0.3 LIPE HSL ENSG00000079435 "Lipase E, hormone sensitive type" Q05469 19 42401514-42427388 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol metabolism, Lipid degradation, Lipid metabolism, Steroid metabolism, Sterol metabolism" Hydrolase "Diabetes mellitus, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "adipose tissue: 834.5;breast: 524.7" "Cell type enhanced" "Detected in many" "Adipocytes: 76.1;Early spermatids: 127.8;Late spermatids: 236.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in many" 7 "ASC diff: 136.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006567, CAB017700" Enhanced Supported Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "CAB017700: AB_2135504, HPA006567: AB_2667618" "unprognostic (4.24e-2)" "unprognostic (2.46e-2)" "unprognostic (8.99e-3)" "unprognostic (3.74e-2)" "unprognostic (1.77e-1)" "unprognostic (3.38e-3)" "unprognostic (5.68e-2)" "unprognostic (2.84e-1)" "unprognostic (3.11e-1)" "unprognostic (9.44e-2)" "prognostic favorable (1.15e-4)" "unprognostic (1.52e-1)" "unprognostic (3.63e-10)" "unprognostic (1.47e-1)" "unprognostic (1.83e-1)" "unprognostic (3.76e-2)" "unprognostic (2.34e-3)" 834.5 45.1 22.7 7.7 71.7 5.0 524.7 77.2 41.5 5.1 0.6 10.9 5.3 6.4 1.2 8.6 5.8 3.7 32.5 23.8 42.6 7.7 1.5 3.7 7.3 100.3 73.9 4.9 6.2 4.7 6.9 2.9 90.0 7.1 1.4 2.0 17.2 2.6 19.7 23.6 24.4 2.6 44.0 14.4 8.5 68.6 57.1 6.9 9.6 23.3 3.7 14.2 7.7 116.9 12.7 9.6 6.0 2.3 136.8 1.3 0.1 5.8 3.1 9.2 8.5 2.3 4.6 20.6 6.3 1.8 4.5 5.6 3.7 11.5 1.0 4.0 6.1 5.8 5.3 0.2 2.7 0.1 13.9 1.2 10.7 1.5 2.1 1.3 2.6 8.5 2.7 12.8 1.2 0.1 14.8 0.5 0.8 9.7 2.7 12.2 1.1 6.9 2.6 13.1 8.5 8.8 5.1 5.7 5.6 0.3 1.5 7.5 4.7 2.5 7.8 1.1 5.3 9.7 8.5 15.6 6.3 0.7 8.7 11.0 8.6 3.8 2.5 4.7 2.3 3.4 3.2 3.7 3.6 4.5 2.8 2.5 1.5 3.6 2.7 2.9 3.0 3.1 22.7 71.7 77.2 41.5 23.8 42.6 100.3 73.9 90.0 44.0 57.1 116.9 76.1 0.0 3.3 4.2 8.1 4.1 12.1 2.4 4.6 11.0 4.8 2.9 2.5 0.0 2.0 1.8 10.4 0.1 4.8 1.3 1.9 8.0 127.8 0.9 3.4 10.2 0.0 5.3 4.6 2.7 0.1 2.0 3.6 1.5 0.0 6.6 17.9 0.0 0.6 8.4 6.7 2.0 6.1 2.2 2.4 236.5 3.1 0.8 5.4 4.7 0.9 4.0 6.2 6.0 37.9 1.8 0.7 1.5 3.0 6.7 18.4 1.5 0.8 13.9 0.0 7.2 2.1 39.4 13.1 2.5 2.4 0.0 5.1 5.2 2.9 10.7 LKAAEAR1 C20orf201 ENSG00000171695 "LKAAEAR motif containing 1" Q8TD35 20 64083380-64084359 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "testis: 32.3" "Group enriched" "Detected in some" 14 "Early spermatids: 496.7;Late spermatids: 694.8" "Group enriched" "Detected in some" 4 "endometrial cancer: 0.8;glioma: 1.2;ovarian cancer: 1.5" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 10 "intermediate monocyte: 8.6;non-classical monocyte: 13.5" "Lineage enriched" "Detected in many" 13 "monocytes: 13.5" "Group enriched" "Detected in some" 4 "REH: 5.6;SCLC-21H: 5.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA056463 Approved Nucleoplasm NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 78: Testis - Spermatogenesis" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 34: Spermatids - Unknown function" Nucleoplasm "HPA056463: AB_2683139" "unprognostic (5.47e-3)" "unprognostic (1.18e-1)" "unprognostic (1.20e-1)" "unprognostic (4.08e-1)" "unprognostic (1.66e-1)" "unprognostic (3.56e-1)" "unprognostic (4.19e-1)" "unprognostic (2.58e-1)" "unprognostic (7.93e-2)" "unprognostic (3.78e-3)" "unprognostic (6.74e-2)" "unprognostic (3.16e-4)" "unprognostic (3.07e-2)" "unprognostic (1.41e-1)" "unprognostic (3.12e-1)" "unprognostic (2.30e-2)" 0.1 0.1 1.6 0.0 0.9 0.1 0.1 0.3 1.9 0.2 0.0 0.0 0.1 0.1 0.0 0.0 2.6 0.0 0.2 1.1 1.6 0.0 0.0 0.6 0.0 1.1 1.6 0.0 0.2 0.0 0.7 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.6 0.2 0.0 32.3 1.7 0.0 0.1 0.0 0.0 0.0 0.1 0.5 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 1.1 0.4 0.2 0.0 0.9 5.6 0.0 0.1 0.0 0.0 5.5 1.3 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.9 0.1 8.6 0.6 0.1 0.6 0.1 1.0 0.0 0.7 0.2 0.0 0.0 13.5 0.2 0.0 0.9 1.6 0.9 0.3 1.9 1.1 1.6 1.1 1.6 1.0 0.6 1.7 0.5 0.5 0.0 0.0 0.0 1.1 0.0 0.2 0.0 0.0 1.1 0.6 1.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 496.7 40.3 1.3 0.5 0.0 0.8 1.1 0.0 0.0 0.6 0.0 0.5 0.0 0.1 1.4 0.1 1.6 0.0 0.9 0.0 0.0 1.8 0.0 694.8 3.7 2.2 0.0 0.0 1.4 0.7 0.0 1.0 0.5 0.1 0.0 3.0 0.4 0.2 0.0 0.2 0.0 1.0 13.1 0.3 0.4 24.0 6.6 0.1 0.0 0.1 0.8 0.1 0.0 0.2 LLCFC1 "C7orf34, CTM-1" ENSG00000165131 "LLLL and CFNLAS motif containing 1" Q96L11 7 142939343-142940868 "Predicted intracellular proteins, Predicted secreted proteins" Fertilization "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 8 "testis: 66.0" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 78: Testis - Spermatogenesis" "unprognostic (5.05e-2)" "unprognostic (9.94e-2)" "unprognostic (5.49e-3)" "unprognostic (2.76e-2)" "unprognostic (1.13e-1)" "unprognostic (1.14e-1)" "unprognostic (3.29e-1)" "unprognostic (2.23e-2)" "unprognostic (1.85e-3)" "unprognostic (3.54e-1)" "unprognostic (2.02e-1)" 0.1 0.0 0.3 0.0 3.6 1.6 0.1 2.2 2.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.4 2.8 0.2 0.0 0.2 0.2 6.5 3.3 0.0 0.0 0.0 0.0 0.0 4.4 0.5 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.0 3.0 1.1 0.0 66.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 3.6 2.2 2.0 0.4 2.8 6.5 3.3 4.4 3.0 3.3 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LMBR1 "ACHP, C7orf2, FLJ11665, ZRS" ENSG00000105983 "Limb development membrane protein 1" Q8WVP7 7 156668946-156893216 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 110.7;Inhibitory neurons: 128.7;Microglial cells: 99.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016592 Approved Approved Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 18: U-2197 - ECM organization" "Cluster 59: Non-specific - Transcription" Cytosol "HPA016592: AB_1852943" "unprognostic (8.81e-3)" "unprognostic (1.73e-2)" "unprognostic (9.49e-2)" "unprognostic (2.02e-1)" "unprognostic (3.77e-3)" "unprognostic (6.90e-2)" "unprognostic (1.30e-2)" "unprognostic (3.28e-1)" "unprognostic (1.21e-2)" "unprognostic (1.12e-2)" "unprognostic (1.69e-1)" "unprognostic (1.02e-1)" "prognostic favorable (1.44e-6)" "unprognostic (3.35e-1)" "unprognostic (3.93e-2)" "unprognostic (1.48e-1)" "unprognostic (7.10e-2)" 10.0 26.0 8.8 8.4 10.4 7.8 10.7 11.3 13.2 13.6 7.8 8.9 8.0 13.2 18.1 9.9 14.1 10.2 11.2 9.7 13.2 15.7 13.8 9.1 9.4 11.0 10.0 16.5 8.8 38.0 7.5 10.1 11.2 12.2 10.3 14.3 8.4 10.7 6.7 8.4 9.3 13.2 8.9 7.6 11.9 17.7 10.6 11.8 17.6 11.4 8.7 11.9 6.0 8.5 26.9 20.6 27.5 33.4 21.1 24.0 16.6 14.5 20.5 14.2 16.8 15.4 42.4 25.3 27.6 19.7 27.3 20.4 28.4 28.9 29.1 19.5 25.5 19.1 11.6 19.7 13.6 23.8 13.6 19.3 27.0 20.4 27.3 22.8 29.6 23.4 35.7 23.8 26.9 24.3 25.1 20.5 29.4 30.4 18.7 13.1 18.1 31.6 22.8 25.1 26.1 51.9 20.4 27.8 15.6 17.8 19.1 14.3 38.4 25.1 9.3 82.7 19.6 25.6 22.6 24.0 40.0 30.2 16.4 1.8 0.7 1.0 0.7 0.4 1.4 0.6 1.2 1.2 1.3 0.8 1.5 1.0 0.6 0.2 0.7 0.9 0.9 0.6 8.8 10.4 11.3 13.2 9.7 13.2 11.0 10.0 11.2 8.9 10.6 8.5 25.6 3.2 8.1 54.5 23.7 10.5 13.7 9.9 43.3 11.5 12.8 8.5 17.1 11.5 7.2 12.9 2.1 14.3 8.4 8.6 5.9 11.0 7.4 17.0 8.6 24.8 8.3 17.4 110.7 10.1 5.6 15.2 23.0 15.7 5.7 43.2 9.3 19.2 10.2 8.4 128.7 9.9 10.2 10.1 8.0 9.7 10.5 9.3 7.2 99.3 8.2 6.7 3.1 72.4 70.4 12.6 6.1 8.6 23.4 20.0 9.7 12.2 9.7 10.9 0.0 11.9 11.0 18.0 28.7 30.9 12.8 23.1 18.0 26.2 11.1 16.6 LMLN "Gp63, LMNL1, Msp" ENSG00000185621 "Leishmanolysin like peptidase" Q96KR4 3 197960200-198043720 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Mitosis" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 39.7;Endometrial ciliated cells: 35.2;Respiratory ciliated cells: 37.5;Spermatocytes: 33.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016481, HPA028844" Uncertain Supported "Focal adhesion sites,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 16: U-266 - Nucleosome" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "Focal adhesion sites" "HPA016481: AB_1852955, HPA028844: AB_10602347" "unprognostic (2.54e-1)" "unprognostic (3.15e-1)" "unprognostic (7.63e-2)" "prognostic favorable (6.77e-4)" "unprognostic (1.14e-2)" "unprognostic (1.19e-1)" "unprognostic (1.30e-1)" "unprognostic (4.07e-2)" "unprognostic (1.94e-1)" "unprognostic (2.31e-1)" "unprognostic (6.36e-2)" "unprognostic (2.98e-1)" "unprognostic (4.82e-3)" "unprognostic (8.78e-2)" "unprognostic (7.65e-2)" "unprognostic (1.01e-1)" "unprognostic (1.63e-1)" 2.1 2.6 2.7 1.2 3.4 1.2 2.2 3.6 4.7 3.1 4.7 2.1 1.0 2.2 10.7 2.2 4.9 2.6 3.3 2.7 3.7 3.4 2.2 2.5 1.3 4.2 3.3 3.3 3.8 3.8 6.5 2.0 4.5 2.3 2.0 9.7 2.4 3.4 2.4 3.4 1.4 2.0 3.0 1.5 2.0 10.1 4.0 1.1 4.1 2.0 1.2 1.9 2.3 3.2 7.7 2.8 3.3 4.0 6.4 9.0 2.9 3.9 3.6 6.9 5.6 2.8 2.7 2.4 17.7 2.8 14.9 2.8 3.1 3.1 10.0 0.3 2.3 1.4 2.3 2.1 4.0 4.4 2.0 4.3 6.8 8.6 5.5 4.0 3.0 6.0 7.5 4.5 6.7 5.7 2.6 3.8 3.8 5.5 6.7 3.0 0.8 2.6 7.1 2.0 5.4 1.5 5.4 4.8 3.9 3.7 12.5 3.2 6.6 8.4 1.3 10.3 6.7 8.0 16.7 0.7 12.0 7.4 7.8 0.0 0.1 0.1 0.2 0.4 0.3 0.4 0.1 0.3 0.4 0.2 0.4 0.5 0.1 0.3 0.2 0.1 0.0 0.2 2.7 3.4 3.6 4.7 2.7 3.7 4.2 3.3 4.5 3.0 4.0 3.2 4.4 16.0 14.8 24.5 1.7 2.0 1.5 2.6 4.0 8.1 6.4 4.8 11.6 2.8 9.2 9.2 16.7 3.6 1.2 2.2 0.0 3.5 39.7 35.2 11.5 3.2 4.8 0.8 25.3 2.7 2.2 5.5 1.5 11.5 2.5 6.3 4.2 3.1 5.0 8.4 23.1 3.6 0.0 1.9 2.3 21.9 4.7 2.3 3.6 9.4 1.1 5.9 1.0 6.6 13.7 2.1 1.0 5.7 2.1 1.8 0.7 3.5 37.5 17.7 0.0 6.6 3.8 33.2 23.6 3.7 1.7 2.9 2.1 10.6 2.8 1.1 LMO1 "RBTN1, RHOM1, TTG1" ENSG00000166407 "LIM domain only 1" P25800 11 8224309-8268716 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 9.8;skeletal muscle: 29.3;tongue: 12.4" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 18.5;Distal tubular cells: 27.4;Early spermatids: 60.7;Horizontal cells: 40.4" "Cancer enriched" "Detected in many" 6 "glioma: 6.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 33.8;SCLC-21H: 12.5;SH-SY5Y: 38.5;SiHa: 7.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 29: Early spermatids - Spermatogenesis" "unprognostic (3.74e-3)" "unprognostic (1.45e-1)" "unprognostic (4.75e-6)" "unprognostic (9.34e-2)" "unprognostic (2.37e-1)" "unprognostic (1.98e-1)" "unprognostic (7.06e-3)" "unprognostic (8.09e-2)" "unprognostic (2.24e-1)" "unprognostic (9.05e-2)" "unprognostic (4.36e-12)" "unprognostic (1.76e-2)" "unprognostic (8.88e-2)" "unprognostic (2.58e-2)" "unprognostic (3.13e-2)" 0.1 1.2 2.4 0.1 2.3 0.0 0.3 4.1 3.4 0.0 1.1 0.2 0.2 0.1 1.6 0.3 0.1 0.0 1.1 3.2 3.2 3.5 0.0 0.0 0.0 5.3 9.8 0.1 0.8 0.0 2.3 0.1 5.2 0.1 0.0 2.0 0.3 0.0 29.3 7.3 0.0 0.2 1.9 0.5 0.7 2.2 5.3 0.0 0.1 12.4 0.0 0.3 0.1 2.4 0.1 0.9 1.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.1 0.1 0.5 0.0 0.0 0.0 1.5 0.0 33.8 0.0 0.0 0.0 0.7 0.0 0.3 0.0 0.0 0.3 0.0 4.3 0.0 0.0 0.0 0.6 1.4 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 12.5 38.5 7.9 4.4 0.2 1.5 0.0 0.0 0.0 0.0 1.0 0.0 0.4 0.1 0.0 0.0 1.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 2.3 4.1 3.4 3.2 3.2 5.3 9.8 5.2 1.9 5.3 2.4 0.1 0.0 0.0 3.3 0.0 18.5 0.1 0.3 1.8 7.1 0.0 0.0 3.0 0.0 0.2 0.0 0.0 0.2 0.0 0.4 27.4 0.1 60.7 0.1 0.1 0.4 0.0 0.0 1.1 1.2 8.4 0.1 0.0 0.5 1.3 0.2 0.0 0.0 0.2 40.4 0.6 0.0 0.0 0.0 0.4 6.8 0.0 0.2 0.0 11.2 0.0 0.5 0.0 3.0 0.3 2.0 1.1 0.4 0.1 0.1 0.0 0.2 2.3 4.0 0.0 0.5 0.7 0.6 1.3 0.3 3.4 0.3 0.0 0.0 0.0 0.0 LMX1B NPS1 ENSG00000136944 "LIM homeobox transcription factor 1 beta" O60663 9 126613928-126701032 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.2;salivary gland: 18.5" "Cell type enhanced" "Detected in some" "Breast glandular cells: 8.3;Breast myoepithelial cells: 7.2;Cardiomyocytes: 1.9;Early spermatids: 1.6;Spermatogonia: 2.1" "Cancer enriched" "Detected in some" 14 "breast cancer: 12.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 3.5;HEK 293: 3.6;MCF7: 11.9;OE19: 10.4;T-47d: 8.1" "Region enhanced" "Detected in some" "pons and medulla: 2.3" "Region enhanced" "Detected in many" "midbrain: 5.0" "HPA073716, HPA075656" Approved Nucleoplasm NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 35: Glandular cells - Unknown function" Nucleoplasm "HPA073716: AB_2686630, HPA075656: " "unprognostic (4.17e-1)" "unprognostic (4.72e-2)" "unprognostic (2.81e-2)" "unprognostic (2.53e-4)" "unprognostic (1.73e-1)" "unprognostic (1.50e-4)" "unprognostic (1.86e-1)" "unprognostic (2.20e-2)" "unprognostic (3.41e-1)" "unprognostic (2.26e-1)" "unprognostic (1.34e-2)" "unprognostic (3.51e-3)" "unprognostic (1.63e-5)" "unprognostic (1.69e-1)" "unprognostic (1.23e-1)" "unprognostic (1.56e-6)" "unprognostic (1.13e-2)" 0.6 0.0 0.1 0.0 0.1 0.1 4.1 0.1 5.6 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 2.0 1.0 1.0 3.6 0.0 0.1 0.0 3.8 9.2 0.0 0.2 1.1 0.2 0.0 3.3 0.0 0.0 0.0 18.5 0.0 0.1 2.1 0.1 0.0 6.8 0.0 0.1 1.4 2.6 0.0 0.4 0.0 0.0 0.0 0.0 0.5 1.2 0.6 0.3 2.7 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.9 0.6 0.0 0.3 0.0 2.5 0.6 3.5 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.5 0.0 1.8 0.0 0.0 0.1 0.0 0.0 0.0 11.9 0.0 0.0 0.0 10.4 0.0 0.0 2.4 0.0 0.0 0.1 0.0 1.1 0.3 0.0 0.2 0.1 8.1 0.1 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 5.6 1.0 1.0 3.8 9.2 3.3 6.8 2.6 0.5 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 8.3 7.2 1.9 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.8 1.6 0.2 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.1 2.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 LNP1 NP3 ENSG00000206535 "Leukemia NUP98 fusion partner 1" A1A4G5 3 100401532-100456319 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "retina: 46.1;testis: 29.0" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 50.1;Early spermatids: 147.6;Horizontal cells: 257.4;Spermatocytes: 91.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.4" "Lineage enriched" "Detected in single" 4 "T-cells: 1.4" "Cell line enhanced" "Detected in many" "PC-3: 18.7;U-266/84: 17.3" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "amygdala: 6.8;cerebral cortex: 8.7;hippocampal formation: 7.3;olfactory bulb: 5.0" HPA047926 Approved "Nuclear speckles,Vesicles,Cytosol" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 16: U-266 - Nucleosome" "Cluster 62: Horizontal cells - Visual perception" Vesicles "Nuclear speckles, Cytosol" "HPA047926: " "unprognostic (1.78e-1)" "unprognostic (3.70e-2)" "unprognostic (8.33e-3)" "unprognostic (4.40e-3)" "unprognostic (6.33e-3)" "unprognostic (1.17e-1)" "unprognostic (1.34e-1)" "unprognostic (1.66e-3)" "unprognostic (1.81e-1)" "unprognostic (1.75e-2)" "unprognostic (1.58e-2)" "unprognostic (1.74e-2)" "unprognostic (8.28e-3)" "unprognostic (1.43e-1)" "unprognostic (7.98e-2)" "unprognostic (2.11e-1)" "unprognostic (6.08e-2)" 2.2 1.9 5.1 0.8 5.9 0.1 1.9 5.3 6.1 2.6 3.0 2.5 0.6 3.1 6.7 1.3 3.0 2.0 8.5 5.2 6.0 4.3 7.7 3.1 0.9 5.2 5.1 3.9 3.3 1.7 6.1 2.7 6.4 1.9 1.5 46.1 2.0 2.3 2.9 0.7 1.2 2.7 4.6 1.2 1.5 29.0 4.7 1.3 3.6 2.1 1.1 3.1 1.7 5.3 3.2 1.7 9.9 0.9 4.1 2.9 0.7 2.0 6.3 2.7 2.8 0.9 0.9 2.4 0.9 1.9 2.8 2.1 1.8 3.2 2.9 2.6 2.1 7.1 0.5 4.0 1.8 5.4 0.8 3.5 0.8 1.2 5.0 2.5 0.3 1.0 2.7 11.6 2.1 2.7 6.2 4.3 7.6 2.1 18.7 4.6 5.4 6.1 1.9 0.4 9.5 4.9 1.6 2.7 4.5 2.3 0.6 0.6 0.7 1.0 10.4 1.0 2.2 14.9 17.3 9.5 3.3 3.3 2.1 0.0 0.0 0.0 0.4 0.0 0.9 0.3 0.3 0.2 0.2 0.1 0.4 0.4 0.0 0.1 0.0 0.0 1.4 0.1 5.1 5.9 5.3 6.1 5.2 6.0 5.2 5.1 6.4 4.6 4.7 5.3 0.9 0.0 0.5 4.2 1.8 1.0 1.3 0.7 2.2 42.2 2.2 1.9 10.5 0.0 1.5 1.8 50.1 1.5 0.3 0.6 7.9 0.8 147.6 0.9 2.3 1.2 2.4 6.1 6.9 1.0 1.9 3.2 3.1 0.7 0.0 1.2 0.0 1.7 0.6 257.4 11.3 1.6 0.0 0.3 0.3 34.2 3.4 0.3 21.4 0.0 0.7 17.1 1.0 7.5 3.7 0.6 0.5 1.2 7.5 0.8 1.1 6.0 3.3 44.3 0.0 1.9 4.6 91.8 3.3 0.6 0.6 0.4 0.7 0.7 0.8 0.5 LOXHD1 "DFNB77, FLJ32670, LH2D1" ENSG00000167210 "Lipoxygenase homology domains 1" Q8IVV2 18 46476972-46657220 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Hearing "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 7.2;kidney: 6.9;testis: 23.0" "Group enriched" "Detected in some" 70 "Early spermatids: 199.3;Late spermatids: 439.4" "Cancer enhanced" "Detected in single" "testis cancer: 0.5" "Region enhanced" "Detected in some" "basal ganglia: 3.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA077128 Approved "Plasma membrane" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane" "HPA077128: " "unprognostic (6.95e-2)" "unprognostic (1.88e-2)" "unprognostic (4.81e-3)" "unprognostic (2.65e-1)" "unprognostic (1.30e-2)" "unprognostic (7.75e-4)" "unprognostic (9.53e-2)" "unprognostic (7.91e-2)" "unprognostic (7.61e-2)" "unprognostic (9.44e-2)" "unprognostic (1.26e-2)" "unprognostic (1.93e-2)" "unprognostic (7.43e-3)" "unprognostic (6.48e-5)" "unprognostic (2.30e-1)" "unprognostic (8.10e-3)" "unprognostic (1.66e-3)" 2.3 0.0 0.5 0.0 3.4 2.8 0.6 0.0 2.1 0.0 0.1 0.1 0.0 0.1 7.2 0.0 1.7 0.2 0.9 0.3 0.0 6.9 0.0 1.0 0.0 0.0 0.1 0.1 0.2 0.2 1.9 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.2 0.1 0.0 0.0 0.8 0.1 23.0 0.3 0.1 0.2 0.2 0.0 0.2 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 3.4 0.0 2.1 0.3 0.0 0.0 0.1 0.0 0.0 0.3 0.9 1.2 3.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 199.3 0.0 0.1 0.9 0.0 0.0 4.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.6 0.0 0.0 0.0 0.0 439.4 1.8 0.3 0.0 0.0 0.3 0.0 0.0 1.5 0.6 0.0 0.0 2.2 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.1 4.5 1.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 LOXL4 "FLJ21889, LOXC" ENSG00000138131 "Lysyl oxidase like 4" Q96JB6 10 98247690-98268194 "Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "Basal respiratory cells: 141.0" "Cancer enhanced" "Detected in all" "melanoma: 44.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "BJ hTERT+: 249.7;CAPAN-2: 301.6" "Not detected" "Not detected" "Not detected" "Not detected" "CAB033876, HPA037609" Approved Approved Vesicles "Secreted to extracellular matrix" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "CAB033876: AB_2135101, HPA037609: AB_2675579" "unprognostic (9.91e-3)" "unprognostic (3.97e-2)" "unprognostic (1.81e-2)" "unprognostic (1.43e-2)" "prognostic unfavorable (6.49e-4)" "unprognostic (7.71e-2)" "unprognostic (1.75e-2)" "unprognostic (8.38e-2)" "unprognostic (1.39e-1)" "prognostic unfavorable (9.57e-4)" "unprognostic (2.51e-1)" "unprognostic (4.97e-2)" "unprognostic (5.25e-2)" "unprognostic (5.77e-3)" "unprognostic (1.28e-1)" "unprognostic (6.10e-2)" "unprognostic (7.40e-3)" 8.2 2.4 0.7 1.6 0.9 0.5 11.9 1.1 0.7 11.8 2.3 10.4 1.9 7.0 3.0 2.0 7.8 1.8 3.0 0.8 1.2 6.6 6.0 4.4 0.4 1.3 1.3 7.1 6.6 1.2 1.9 5.8 1.3 6.6 1.8 2.6 19.6 10.8 8.3 4.0 3.2 7.6 1.0 2.7 2.9 5.5 1.0 1.4 7.0 1.5 0.7 5.0 7.4 1.0 0.0 1.6 0.1 0.3 6.9 29.5 0.9 32.1 249.7 2.6 26.6 5.4 301.6 0.1 28.4 25.1 1.1 0.3 0.1 0.0 2.2 0.0 0.2 0.0 4.4 13.3 6.7 0.0 0.0 3.3 0.0 4.4 0.0 0.4 0.1 0.0 0.3 0.0 0.4 0.0 0.0 2.3 0.6 0.1 0.5 0.1 2.9 0.0 0.0 0.0 0.1 1.0 0.1 0.0 0.0 8.7 0.2 0.7 0.7 0.2 53.7 3.2 1.1 0.0 0.0 0.2 0.5 0.0 35.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.7 0.9 1.1 0.7 0.8 1.2 1.3 1.3 1.3 1.0 1.0 1.0 0.3 6.4 1.5 0.7 0.3 0.9 2.1 141.0 0.0 0.4 6.5 6.5 1.6 4.3 17.5 31.3 0.0 0.2 1.7 0.1 0.0 11.1 0.3 1.5 1.2 0.9 0.0 0.0 0.1 0.5 0.4 6.0 0.0 4.2 1.3 1.1 2.2 0.4 0.2 0.0 0.1 0.2 8.2 0.0 2.1 0.4 4.1 0.2 0.0 9.4 0.0 5.4 0.0 0.0 0.0 3.0 0.0 1.5 0.3 7.9 0.0 0.4 6.3 0.1 0.0 5.2 2.2 0.1 0.2 0.1 0.9 0.4 0.2 0.7 0.0 3.4 LPGAT1 "FAM34A, FAM34A1, KIAA0205, NET8" ENSG00000123684 "Lysophosphatidylglycerol acyltransferase 1" Q92604 1 211743457-211830763 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 416.1;Oligodendrocytes: 474.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 16.1" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 77: Retina - Visual perception" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 29: Early spermatids - Spermatogenesis" "unprognostic (4.60e-2)" "unprognostic (1.04e-1)" "unprognostic (3.90e-1)" "unprognostic (1.28e-1)" "unprognostic (1.36e-1)" "unprognostic (1.66e-1)" "unprognostic (9.47e-3)" "unprognostic (1.12e-2)" "unprognostic (1.08e-1)" "unprognostic (2.67e-1)" "unprognostic (2.54e-1)" "unprognostic (1.31e-1)" "unprognostic (1.64e-2)" "unprognostic (1.18e-1)" "unprognostic (2.02e-1)" "unprognostic (1.50e-2)" "unprognostic (3.70e-2)" 20.0 19.7 17.0 13.4 29.4 20.0 13.4 13.8 19.5 11.4 21.3 9.3 23.6 9.0 10.1 7.7 8.5 12.1 11.8 14.6 18.0 9.8 36.4 8.8 10.5 18.2 22.4 6.0 13.7 13.9 8.9 9.1 17.8 10.1 10.3 41.1 9.4 12.4 9.9 6.2 35.0 12.2 13.2 16.7 7.4 22.3 21.7 8.2 25.8 14.9 9.8 13.8 7.4 39.2 28.2 30.4 9.8 23.5 17.4 24.2 14.1 19.7 31.2 18.0 16.5 9.1 22.9 11.5 11.3 30.7 20.1 15.0 33.2 17.6 22.6 22.6 11.2 12.0 24.5 20.8 20.9 29.9 19.8 14.3 21.2 16.6 21.6 33.1 21.9 16.2 14.0 0.2 24.1 8.8 11.4 11.1 10.7 12.0 4.9 27.2 38.8 3.5 20.1 23.0 56.6 29.3 32.3 33.9 33.9 15.1 17.3 19.3 21.3 32.7 14.4 30.3 32.5 16.1 21.2 30.2 16.2 25.0 22.8 12.3 2.7 16.1 1.4 2.2 1.1 1.8 0.9 1.0 3.2 1.0 0.2 0.8 12.1 5.3 1.7 2.4 0.2 0.9 17.0 29.4 13.8 19.5 14.6 18.0 18.2 22.4 17.8 13.2 21.7 39.2 50.0 28.9 21.0 28.7 42.2 12.2 77.7 11.5 38.1 206.3 32.2 18.9 40.4 72.9 16.9 12.9 62.6 2.3 73.2 25.3 1.9 71.9 416.1 39.1 39.2 31.6 13.8 15.3 73.5 59.4 4.7 30.9 19.9 28.0 12.7 22.0 25.0 56.2 20.9 35.3 92.3 14.6 26.4 49.7 27.3 60.2 47.2 44.9 30.2 46.9 58.6 34.7 49.4 70.4 474.0 47.8 19.5 55.7 15.0 53.3 126.1 24.2 38.2 127.6 19.7 47.1 33.2 67.2 33.3 30.7 7.5 1.1 32.5 129.4 23.4 63.1 LPIN1 KIAA0188 ENSG00000134324 "Lipin 1" Q14693 2 11677595-11827409 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism, Transcription, Transcription regulation" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 193.5;tongue: 137.2" "Cell type enriched" "Detected in all" 5 "Late spermatids: 1705.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024591, HPA038021" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "Plasma membrane" "HPA024591: , HPA038021: AB_10669514" "unprognostic (1.97e-1)" "unprognostic (2.47e-1)" "unprognostic (1.32e-1)" "unprognostic (1.87e-2)" "unprognostic (9.17e-2)" "unprognostic (2.69e-2)" "unprognostic (8.20e-2)" "unprognostic (5.28e-3)" "unprognostic (1.09e-1)" "unprognostic (1.07e-2)" "unprognostic (2.45e-3)" "unprognostic (2.55e-2)" "unprognostic (1.06e-1)" "unprognostic (5.58e-3)" "unprognostic (1.25e-1)" "unprognostic (9.60e-2)" "unprognostic (4.02e-1)" 36.2 15.0 29.0 14.9 30.6 8.6 36.7 24.2 24.9 25.1 21.9 16.7 11.9 16.6 19.0 40.5 15.6 13.0 20.1 21.0 32.1 14.9 27.0 16.1 22.3 31.8 38.2 31.5 9.9 23.1 34.2 11.7 35.3 13.7 8.5 14.8 27.3 14.1 193.5 13.4 19.7 13.0 14.1 14.8 14.9 57.4 35.0 16.1 14.6 137.2 26.3 19.9 23.1 18.8 16.2 18.0 15.9 34.9 71.4 77.9 7.8 22.2 38.7 14.0 24.3 6.9 15.4 8.2 2.9 18.6 41.6 17.3 17.4 49.2 12.8 32.9 9.8 20.3 11.5 9.7 25.1 14.1 90.1 71.1 21.7 57.9 22.6 41.7 28.0 19.6 27.4 68.3 10.4 6.4 13.5 12.0 16.2 5.5 18.9 18.1 28.6 52.0 36.9 10.0 42.8 33.6 8.0 19.7 51.9 15.0 4.9 7.9 19.5 22.1 19.9 14.4 19.0 108.0 92.0 15.2 31.3 24.7 16.6 11.2 2.9 13.4 10.3 2.3 11.2 7.3 9.9 10.1 2.7 5.1 8.6 7.2 1.1 9.5 2.3 10.3 12.2 3.7 29.0 30.6 24.2 24.9 21.0 32.1 31.8 38.2 35.3 14.1 35.0 18.8 15.6 22.4 56.8 167.8 46.1 19.1 45.1 12.6 18.8 48.6 32.8 22.9 59.6 31.5 43.9 11.0 85.5 8.7 68.0 21.2 7.9 23.0 338.4 27.8 44.4 25.8 36.2 9.7 55.7 28.0 6.0 28.8 19.4 76.5 35.4 13.1 17.5 48.7 8.9 48.8 71.7 25.2 22.4 15.7 39.4 1705.8 119.0 25.5 17.8 21.5 15.4 14.7 66.9 41.7 43.5 36.5 29.7 179.8 76.0 34.9 5.4 4.8 52.0 49.0 32.9 32.4 18.4 20.6 19.7 5.5 11.9 12.3 73.2 26.6 16.3 31.3 LPL LIPD ENSG00000175445 "Lipoprotein lipase" P06858 8 19901717-19967259 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" "Heparin-binding, Hydrolase" "Disease variant, FDA approved drug targets, Hyperlipidemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 937.4;heart muscle: 407.8" "Cell type enhanced" "Detected in many" "Adipocytes: 453.0;Cardiomyocytes: 489.0;Granulosa cells: 495.2;Horizontal cells: 206.9;Sertoli cells: 236.7" "Cancer enhanced" "Detected in all" "glioma: 39.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 4.2" "Lineage enriched" "Detected in single" 6 "monocytes: 4.2" "Cell line enriched" "Detected in some" 5 "AF22: 391.6" "Region enhanced" "Detected in many" "basal ganglia: 45.3" "Group enriched" "Detected in all" 5 "basal ganglia: 79.2;spinal cord: 59.3" HPA048749 Supported Vesicles "Secreted to blood" NA NA 4200000 "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" Vesicles "HPA048749: AB_2680511" "unprognostic (5.52e-2)" "unprognostic (3.16e-1)" "unprognostic (6.41e-2)" "unprognostic (3.03e-1)" "unprognostic (4.14e-2)" "unprognostic (1.01e-2)" "unprognostic (1.88e-4)" "unprognostic (1.05e-1)" "unprognostic (6.78e-2)" "unprognostic (8.20e-2)" "unprognostic (2.54e-2)" "unprognostic (5.28e-1)" "unprognostic (1.18e-1)" "unprognostic (4.20e-3)" "unprognostic (4.16e-3)" "unprognostic (1.19e-1)" "prognostic unfavorable (6.07e-4)" 937.4 15.9 6.8 9.1 53.2 0.9 255.4 20.3 12.2 2.7 8.9 12.0 1.5 3.7 0.5 2.8 2.7 8.6 407.8 10.7 9.5 19.1 0.7 62.1 8.5 7.4 7.7 10.6 6.3 181.5 4.1 14.7 7.9 3.8 5.8 11.1 24.4 64.7 86.4 8.3 13.3 4.1 5.5 1.6 8.4 1.0 11.5 4.3 10.6 127.3 2.8 6.1 4.7 8.8 0.0 0.0 391.6 0.1 8.1 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.7 0.0 0.8 0.0 0.0 0.1 0.3 0.0 71.5 0.0 0.2 8.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.0 0.1 0.7 9.6 0.0 0.0 0.0 0.0 68.4 0.0 0.0 8.4 0.2 0.0 0.0 0.1 13.5 0.0 1.8 0.0 0.0 8.1 0.0 3.5 0.0 0.1 0.1 0.1 0.1 32.6 0.0 0.9 0.7 0.0 1.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.2 6.8 53.2 20.3 12.2 10.7 9.5 7.4 7.7 7.9 5.5 11.5 8.8 453.0 12.8 104.9 1.0 0.4 1.5 0.1 0.0 0.6 2.8 114.7 5.7 489.0 0.0 0.6 0.0 2.1 0.4 0.9 0.1 15.6 0.0 0.8 0.2 2.5 56.1 0.0 0.0 1.9 0.0 0.7 13.6 0.0 0.3 6.3 495.2 2.9 0.0 108.5 206.9 0.4 1.0 0.0 14.8 4.2 1.3 1.2 38.2 14.2 1.9 2.0 2.3 0.0 9.0 0.1 0.0 0.0 0.0 0.0 0.3 0.3 0.4 2.9 2.7 236.7 91.4 68.1 0.4 0.2 0.2 0.6 0.4 2.3 4.3 2.8 0.1 LRATD2 "BCMP101, FAM84B, NSE2" ENSG00000168672 "LRAT domain containing 2" Q96KN1 8 126552443-126558478 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 43.7" "Cell type enhanced" "Detected in some" "Adipocytes: 20.9;Cardiomyocytes: 6.8;Cytotrophoblasts: 5.4;Endothelial cells: 4.0;Syncytiotrophoblasts: 2.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 78.5;AN3-CA: 104.6;MCF7: 112.1;PC-3: 72.5;SuSa: 162.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050782, HPA062115" Approved Approved Nucleoplasm NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 7: Kidney - Transmembrane transport" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "HPA050782: AB_2681235, HPA062115: AB_2684686" "unprognostic (2.46e-3)" "unprognostic (6.37e-2)" "unprognostic (7.36e-2)" "prognostic unfavorable (9.71e-4)" "unprognostic (2.75e-3)" "unprognostic (1.54e-1)" "unprognostic (1.79e-1)" "unprognostic (4.52e-2)" "unprognostic (1.32e-1)" "unprognostic (4.49e-2)" "unprognostic (2.42e-3)" "unprognostic (1.07e-2)" "prognostic favorable (1.96e-8)" "unprognostic (2.04e-3)" "unprognostic (1.58e-1)" "unprognostic (1.18e-1)" "prognostic favorable (1.75e-5)" 6.1 2.5 6.1 3.2 7.1 3.0 16.3 7.1 5.2 7.3 25.4 7.6 13.1 7.3 6.8 19.5 8.3 8.1 4.0 5.2 7.1 27.3 8.2 12.0 3.8 8.9 7.5 2.9 16.3 9.2 4.5 7.5 6.9 8.3 8.2 19.1 43.7 6.8 2.5 7.2 7.4 4.6 7.0 3.2 17.6 2.1 5.8 3.2 7.4 5.2 6.3 6.4 5.8 12.6 78.5 9.8 5.8 104.6 0.0 0.0 6.9 1.1 2.7 0.8 1.2 3.0 44.9 0.0 48.5 0.2 8.4 34.3 3.1 14.7 1.3 0.1 63.0 0.0 0.2 0.5 1.4 0.1 1.6 0.6 20.3 0.0 9.0 17.6 6.3 19.7 0.1 0.0 0.5 112.1 2.6 0.0 5.3 65.7 72.5 0.0 2.3 0.8 41.8 32.5 29.7 0.0 2.4 34.9 32.4 162.9 52.0 0.7 0.0 0.3 9.4 0.1 2.0 1.3 0.2 0.1 0.9 5.0 19.6 1.7 0.0 1.5 1.4 0.0 1.4 0.3 1.8 2.7 0.0 0.8 2.0 2.1 0.1 1.1 0.0 0.0 2.6 0.9 6.1 7.1 7.1 5.2 5.2 7.1 8.9 7.5 6.9 7.0 5.8 12.6 20.9 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.0 5.4 2.6 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 2.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 2.9 1.5 0.0 0.0 0.0 LRGUK "CFAP246, FLJ32786" ENSG00000155530 "Leucine rich repeats and guanylate kinase domain containing" Q96M69 7 134127299-134264591 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 5.2;fallopian tube: 3.7;testis: 4.8" "Cell type enhanced" "Detected in some" "Early spermatids: 27.6;Endometrial ciliated cells: 13.8;Excitatory neurons: 21.8;Inhibitory neurons: 13.9;Ionocytes: 12.2;Respiratory ciliated cells: 21.5;Spermatocytes: 8.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NTERA-2: 1.9;SH-SY5Y: 1.8;SK-MEL-30: 1.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA029505, HPA029506" Uncertain NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 5: NTERA-2 - Transcription" "Cluster 49: Ciliated cells - Cilium organization" "HPA029505: AB_10599606, HPA029506: AB_10601752" "unprognostic (4.08e-3)" "unprognostic (1.87e-1)" "unprognostic (6.94e-2)" "unprognostic (1.01e-2)" "unprognostic (2.31e-2)" "unprognostic (2.64e-2)" "unprognostic (7.85e-4)" "unprognostic (6.92e-2)" "unprognostic (2.43e-1)" "unprognostic (4.28e-2)" "unprognostic (5.57e-3)" "unprognostic (1.10e-1)" "unprognostic (1.27e-3)" "unprognostic (2.22e-3)" "unprognostic (3.83e-2)" "unprognostic (3.01e-3)" "unprognostic (2.10e-2)" 0.2 0.2 0.8 0.2 0.9 0.5 0.4 0.0 0.6 0.4 5.2 0.2 0.1 0.3 1.5 0.1 3.7 0.2 0.1 1.3 1.0 0.5 0.4 0.5 0.1 3.0 3.0 0.1 0.8 0.1 0.7 0.0 1.7 0.6 0.2 2.1 0.5 0.1 0.0 0.4 0.2 0.1 1.6 0.5 0.2 4.8 1.4 0.2 0.5 0.0 0.1 0.1 0.1 0.6 0.1 0.1 0.2 0.4 0.0 0.1 0.1 0.0 0.0 0.2 0.1 0.0 0.3 0.1 0.1 0.0 0.3 0.1 0.1 0.0 0.3 0.2 0.2 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.2 0.3 0.0 0.0 0.1 0.2 0.0 0.3 0.3 0.0 0.1 0.2 1.9 0.0 0.4 0.2 0.0 0.0 0.3 0.1 0.6 1.8 0.5 0.0 1.9 0.2 0.1 0.4 0.0 0.1 0.2 0.1 0.2 0.4 0.6 0.6 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.9 0.0 0.6 1.3 1.0 3.0 3.0 1.7 1.6 1.4 0.6 0.2 0.0 0.0 5.5 0.1 0.0 0.1 0.4 0.6 0.0 0.8 0.5 0.4 1.5 1.6 0.0 0.0 0.0 0.1 0.0 0.0 0.2 27.6 13.8 0.5 0.3 0.0 0.0 21.8 0.4 0.0 0.4 0.0 1.2 0.0 0.8 0.0 0.4 0.2 0.0 13.9 0.0 12.2 0.0 0.3 2.1 0.3 0.2 1.8 5.6 0.0 0.9 0.0 5.0 2.5 0.0 0.0 0.4 0.1 0.1 0.0 0.2 21.5 2.1 0.0 0.3 0.6 8.6 0.9 0.3 0.4 0.3 0.1 0.5 0.0 0.2 LRIT3 "CSNB1F, FIGLER4, FLJ44691" ENSG00000183423 "Leucine rich repeat, Ig-like and transmembrane domains 3" Q3SXY7 4 109848107-109872315 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Sensory transduction, Vision" "Congenital stationary night blindness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 22 "retina: 17.6" "Group enriched" "Detected in some" 6 "Cone photoreceptor cells: 33.3;Muller glia cells: 10.2;Rod photoreceptor cells: 9.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA013454 Enhanced Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 77: Retina - Visual perception" "Cluster 9: Photoreceptor cells - Phototransduction" "Nucleoplasm, Mitochondria, Cytosol" "HPA013454: AB_1853277" "unprognostic (5.41e-2)" "unprognostic (6.82e-2)" "unprognostic (4.20e-2)" "unprognostic (6.50e-2)" "unprognostic (3.42e-1)" "unprognostic (7.67e-3)" "unprognostic (1.54e-1)" "unprognostic (5.25e-2)" "unprognostic (3.16e-2)" "unprognostic (4.49e-2)" "unprognostic (6.92e-3)" "unprognostic (3.34e-3)" "unprognostic (2.14e-1)" "unprognostic (4.01e-2)" "unprognostic (1.69e-1)" "unprognostic (1.35e-1)" "unprognostic (1.14e-2)" 0.2 0.2 0.4 0.0 0.5 0.1 0.3 0.3 0.6 0.4 0.2 0.2 0.0 0.2 0.3 0.2 0.3 0.0 0.1 0.4 0.2 0.7 0.3 0.2 0.1 0.3 0.3 0.2 0.3 0.0 0.2 0.0 0.4 0.3 0.0 17.6 0.2 0.1 0.3 0.6 0.2 0.0 0.2 0.3 0.2 0.5 0.3 0.1 0.3 0.0 0.0 0.3 0.2 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.3 0.6 0.4 0.2 0.3 0.3 0.4 0.2 0.3 0.5 0.0 0.0 0.0 2.3 0.1 0.0 0.0 0.0 0.0 1.2 0.2 0.1 0.1 0.0 0.0 0.0 33.3 0.0 0.0 0.0 1.9 0.0 0.2 0.1 0.0 0.0 0.0 0.0 2.7 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 2.6 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.0 0.0 10.2 0.0 0.5 1.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 9.6 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 LRRC32 "D11S833E, GARP" ENSG00000137507 "Leucine rich repeat containing 32" Q14392 11 76657524-76670747 "Predicted intracellular proteins, Predicted membrane proteins" "Growth factor binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 78.0;Endothelial cells: 88.3;Extravillous trophoblasts: 164.2;Hepatic stellate cells: 95.3;Sertoli cells: 39.5;Smooth muscle cells: 47.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 2.2" "Lineage enhanced" "Detected in single" "T-cells: 2.2" "Group enriched" "Detected in some" 6 "ASC diff: 115.0;ASC TERT1: 70.3;HSkMC: 44.0;HUVEC TERT2: 51.4;U-2197: 108.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA055775, HPA058434" Enhanced Nucleoplasm "Intracellular and membrane" NA NA 98000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "HPA055775: AB_2732600, HPA058434: AB_2732622" "unprognostic (3.18e-1)" "unprognostic (1.38e-1)" "unprognostic (2.60e-2)" "unprognostic (4.19e-3)" "unprognostic (1.16e-1)" "unprognostic (8.84e-2)" "unprognostic (1.39e-2)" "unprognostic (2.24e-2)" "unprognostic (6.29e-2)" "unprognostic (1.83e-2)" "unprognostic (1.58e-1)" "unprognostic (9.86e-2)" "prognostic unfavorable (3.93e-5)" "unprognostic (7.99e-3)" "unprognostic (1.15e-2)" "unprognostic (5.22e-3)" "prognostic unfavorable (2.64e-4)" 104.5 34.3 12.6 10.5 12.6 2.4 63.6 11.2 11.8 56.2 8.4 23.2 8.9 36.4 6.2 10.3 31.6 29.0 55.7 9.6 10.6 64.7 11.3 109.0 4.3 12.2 13.8 13.5 12.0 7.5 16.7 53.0 13.0 24.9 6.1 1.3 12.8 11.0 23.6 26.6 21.4 15.2 10.9 28.9 21.3 3.6 15.0 2.0 42.3 6.2 1.5 36.7 28.8 11.5 0.0 0.0 1.3 0.0 115.0 70.3 1.4 0.4 0.8 0.1 0.1 0.0 0.0 0.2 3.1 1.9 0.0 0.1 0.2 0.0 0.1 0.0 0.0 11.8 0.6 0.0 2.2 0.0 0.1 44.0 0.0 4.1 0.2 0.9 51.4 0.0 0.7 0.0 0.1 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.1 7.6 0.2 0.0 13.8 7.5 0.8 108.3 0.0 0.1 0.0 1.9 5.5 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.2 4.3 12.6 12.6 11.2 11.8 9.6 10.6 12.2 13.8 13.0 10.9 15.0 11.5 78.0 0.0 4.3 0.0 1.7 14.5 0.3 0.0 1.8 0.0 0.6 0.6 10.4 0.0 1.3 0.0 0.0 1.9 0.1 0.2 0.0 0.3 1.3 0.1 1.9 88.3 0.0 5.3 0.0 0.0 164.2 26.4 0.5 0.3 2.5 0.5 95.3 0.6 3.6 0.0 0.1 0.4 0.0 3.1 19.0 1.9 9.0 2.9 17.8 14.0 0.0 0.4 0.0 0.0 0.1 0.0 2.2 9.1 0.2 1.4 0.0 0.4 0.7 0.1 39.5 2.1 47.6 0.4 4.7 0.6 12.5 8.3 1.6 0.4 0.1 1.2 LRRC34 MGC27085 ENSG00000171757 "Leucine rich repeat containing 34" Q8IZ02 3 169793003-169812986 "Predicted intracellular proteins" Differentiation "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 12.8" "Cell type enhanced" "Detected in many" "Early spermatids: 137.9;Respiratory ciliated cells: 129.6;Spermatocytes: 104.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HEL: 8.1;HL-60: 8.9;JURKAT: 7.1;NTERA-2: 7.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA035747 Approved Approved "Cell Junctions,Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 37: B-cells - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 36: HEL - Hemostasis" "Cluster 49: Ciliated cells - Cilium organization" "Cell Junctions, Microtubules" "Cytokinetic bridge, Mitotic spindle" "HPA035747: AB_10670120" "unprognostic (1.04e-2)" "unprognostic (5.71e-2)" "unprognostic (5.67e-2)" "unprognostic (5.64e-2)" "unprognostic (9.74e-3)" "unprognostic (5.46e-2)" "unprognostic (9.74e-2)" "unprognostic (8.24e-2)" "unprognostic (6.39e-3)" "unprognostic (2.57e-1)" "unprognostic (6.05e-2)" "unprognostic (1.23e-1)" "unprognostic (8.39e-2)" "unprognostic (1.16e-2)" "unprognostic (3.48e-1)" "unprognostic (3.37e-1)" "unprognostic (2.79e-1)" 1.5 0.4 1.6 0.6 2.1 1.4 1.1 1.6 2.7 0.9 2.8 0.5 0.2 0.7 0.3 0.2 5.5 0.3 1.1 1.2 2.1 0.7 0.2 1.0 0.8 2.1 2.5 0.8 0.2 0.3 2.8 0.2 2.2 0.6 0.1 5.6 0.3 0.7 0.4 0.5 0.4 0.2 2.1 0.7 0.4 12.8 1.9 0.6 0.9 0.4 0.3 0.4 0.4 1.8 2.3 0.4 0.5 0.0 0.9 3.0 0.0 0.9 1.9 2.4 2.1 0.1 0.0 1.5 0.1 0.6 3.1 0.0 1.8 0.0 0.8 0.4 5.6 8.1 0.2 0.0 0.6 8.9 1.8 0.9 0.4 0.8 0.0 0.1 1.6 7.1 0.2 0.0 0.9 0.0 0.8 1.1 7.7 0.0 2.6 4.0 0.0 0.4 2.1 0.2 4.0 3.1 0.5 0.3 0.0 0.2 0.0 4.2 0.5 0.4 0.0 0.3 0.1 0.1 0.1 1.9 3.5 0.1 2.2 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.0 1.6 0.1 0.1 1.6 2.1 1.6 2.7 1.2 2.1 2.1 2.5 2.2 2.1 1.9 1.8 3.9 3.2 2.6 8.5 1.5 0.4 0.9 5.3 0.0 6.9 0.4 0.9 3.2 0.0 12.9 5.5 37.5 0.2 1.6 0.1 1.9 0.5 137.9 33.8 5.8 3.0 4.2 4.2 15.1 0.2 0.3 5.0 0.5 1.0 1.3 1.0 10.4 0.3 2.4 11.8 12.5 0.4 6.1 0.8 1.2 36.3 10.5 1.2 0.0 3.7 3.8 7.4 0.0 9.5 3.6 0.3 0.0 10.5 0.7 0.4 0.0 3.6 129.6 18.8 0.0 3.6 3.7 104.4 9.2 0.1 0.3 0.5 0.9 1.9 0.2 0.4 LRRC56 "DKFZp761L1518, FLJ00101" ENSG00000161328 "Leucine rich repeat containing 56" Q8IYG6 11 537527-554912 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 12.3;testis: 22.3" "Group enriched" "Detected in many" 6 "Early spermatids: 68.0;Late spermatids: 141.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 1.8;Daudi: 1.3;Karpas-707: 2.4;SK-BR-3: 1.6;T-47d: 2.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA038728 Approved NA NA "Cluster 71: Testis - DNA repair" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 31: Spermatids - Spermatogenesis" "HPA038728: AB_10671864" "unprognostic (2.77e-2)" "unprognostic (9.54e-3)" "unprognostic (1.28e-2)" "prognostic favorable (7.39e-4)" "unprognostic (3.18e-2)" "unprognostic (4.65e-3)" "unprognostic (2.29e-2)" "prognostic favorable (6.19e-4)" "unprognostic (2.65e-3)" "unprognostic (1.86e-1)" "prognostic favorable (6.32e-4)" "unprognostic (1.17e-1)" "unprognostic (7.89e-2)" "unprognostic (1.33e-1)" "unprognostic (1.22e-1)" "unprognostic (4.56e-1)" "unprognostic (1.52e-3)" 0.8 0.8 0.5 0.1 1.9 0.2 1.6 0.3 0.5 2.4 0.6 1.7 0.1 0.9 1.3 2.7 6.4 0.0 0.5 0.8 0.3 3.2 1.6 2.9 0.0 0.5 0.3 1.8 2.4 0.0 12.3 0.0 0.1 3.7 0.0 0.1 2.0 0.3 1.2 2.5 2.2 0.0 0.4 2.2 2.1 22.3 0.6 0.1 2.7 0.0 0.2 1.2 2.0 0.3 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 1.3 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.7 0.4 1.1 0.4 0.8 0.0 0.2 0.0 0.0 0.5 0.0 2.4 0.0 0.0 0.1 0.7 0.0 0.7 0.7 0.0 0.0 0.5 0.2 0.0 0.3 0.2 0.0 1.6 0.0 0.0 2.0 0.0 0.1 0.3 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.5 1.9 0.3 0.5 0.8 0.3 0.5 0.3 0.1 0.4 0.6 0.3 0.5 0.0 3.4 3.3 3.0 1.7 1.5 1.5 0.0 1.1 2.1 0.9 0.6 1.5 2.4 3.7 16.7 0.3 0.6 4.9 0.0 1.1 68.0 11.6 0.6 0.5 12.5 0.4 5.2 0.4 0.2 1.1 1.5 1.3 0.0 0.5 1.1 0.3 0.3 6.7 3.8 2.1 6.1 0.6 0.3 141.2 1.2 0.3 1.8 1.0 0.0 2.7 1.0 1.5 2.8 0.5 1.4 1.2 0.1 1.2 0.2 0.8 14.4 7.0 0.0 0.2 0.6 6.6 2.2 0.6 0.9 0.5 1.4 0.7 0.6 0.8 LRRC75B "C22orf36, FAM211B, MGC131773" ENSG00000178026 "Leucine rich repeat containing 75B" Q2VPJ9 22 24585620-24593208 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cholangiocytes: 34.3;Hepatocytes: 25.6;Muller glia cells: 39.9;Proximal enterocytes: 46.7;Proximal tubular cells: 44.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 5.3;MCF7: 5.0;SH-SY5Y: 4.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002540 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 43: Testis - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Cytosol" "HPA002540: AB_1079263" "unprognostic (1.21e-1)" "unprognostic (2.00e-1)" "unprognostic (2.47e-1)" "unprognostic (2.34e-1)" "unprognostic (2.74e-2)" "unprognostic (5.21e-2)" "unprognostic (4.52e-2)" "unprognostic (2.48e-2)" "unprognostic (2.49e-1)" "unprognostic (2.48e-2)" "unprognostic (2.67e-2)" "unprognostic (1.35e-1)" "unprognostic (1.47e-1)" "unprognostic (1.74e-1)" "unprognostic (1.28e-1)" "unprognostic (7.40e-2)" "unprognostic (9.69e-2)" 1.8 0.7 5.8 0.0 5.5 0.3 1.8 5.7 7.4 1.9 3.6 3.2 0.0 1.0 0.5 2.1 1.5 0.0 2.9 5.2 6.0 5.6 3.6 0.8 0.0 6.0 6.1 3.2 3.5 0.0 1.3 0.1 5.7 2.8 0.1 0.6 2.0 0.4 2.5 1.8 1.6 0.0 5.9 0.5 2.5 7.5 5.9 0.1 1.6 0.0 0.1 3.5 1.9 5.8 0.1 2.8 0.0 1.5 0.3 1.1 0.2 0.4 0.4 0.9 1.0 2.0 0.0 0.0 0.7 0.8 0.8 3.0 0.2 1.5 0.0 0.9 1.8 0.2 0.3 5.3 2.6 0.0 0.0 0.0 1.1 1.0 0.1 0.5 0.7 0.0 0.1 0.0 0.1 5.0 0.0 1.0 1.3 3.4 1.1 0.0 0.1 0.0 1.2 0.3 1.4 4.2 1.4 0.4 0.5 0.3 0.0 0.5 1.5 1.6 0.9 0.6 0.5 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 5.8 5.5 5.7 7.4 5.2 6.0 6.0 6.1 5.7 5.9 5.9 5.8 1.6 12.8 5.9 9.4 0.3 0.0 2.5 0.0 2.2 2.8 16.2 18.7 4.4 34.3 0.0 7.3 0.0 2.5 0.9 10.7 11.7 9.8 1.6 2.3 3.6 1.8 1.2 1.3 3.8 8.9 0.4 7.1 14.3 6.1 0.0 7.2 2.9 25.6 1.1 1.7 4.1 8.0 0.0 1.6 0.0 7.9 12.8 1.4 0.0 1.0 0.3 39.9 0.0 7.1 2.2 4.0 6.2 9.8 0.6 8.0 46.7 44.5 0.0 1.8 0.0 4.5 4.2 0.5 1.3 2.5 0.0 1.1 0.8 2.0 6.4 1.3 LRRC8D "FLJ10470, LRRC5" ENSG00000171492 "Leucine rich repeat containing 8 VRAC subunit D" Q7L1W4 1 89821014-89936611 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 80.4" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 80.8;Oligodendrocyte precursor cells: 146.8;Oligodendrocytes: 346.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA No "Cluster 20: T-cells - T-cell receptor" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "unprognostic (2.92e-3)" "unprognostic (9.50e-2)" "unprognostic (1.06e-3)" "prognostic unfavorable (3.21e-5)" "unprognostic (4.98e-2)" "unprognostic (7.03e-2)" "unprognostic (7.71e-3)" "unprognostic (7.74e-2)" "unprognostic (9.67e-2)" "unprognostic (1.01e-2)" "unprognostic (1.42e-1)" "unprognostic (2.77e-1)" "unprognostic (4.91e-2)" "unprognostic (9.52e-3)" "unprognostic (1.23e-1)" "unprognostic (2.65e-2)" "unprognostic (9.61e-2)" 5.9 26.9 25.1 15.8 45.2 14.2 12.9 39.2 37.0 12.1 9.6 17.9 19.0 8.8 10.3 7.9 7.8 8.0 7.6 30.6 30.2 25.9 23.5 9.8 24.9 43.3 40.3 5.9 13.0 7.7 16.3 10.3 41.3 5.6 18.2 12.0 24.5 5.8 8.7 5.6 18.0 11.4 39.7 23.9 11.5 10.3 36.5 27.7 15.8 3.4 20.4 11.2 3.3 80.4 73.5 47.0 18.8 44.5 32.9 27.7 63.5 49.1 73.9 27.3 34.1 20.2 18.3 57.7 54.4 82.1 31.0 93.7 43.6 58.9 34.4 45.3 24.1 67.8 40.4 43.2 64.2 78.2 20.5 17.4 48.1 23.3 50.3 37.6 47.1 32.8 37.6 17.7 30.1 22.0 32.5 50.4 32.6 16.4 42.6 43.6 27.3 41.5 69.2 25.7 35.0 24.4 61.0 62.4 137.8 32.4 15.0 76.4 21.0 29.1 9.9 60.0 37.6 21.4 39.5 34.7 11.3 97.0 26.2 0.0 8.9 1.6 7.0 10.4 11.6 6.9 16.0 8.5 8.1 5.6 15.2 11.5 3.5 13.1 8.4 9.4 17.4 10.6 25.1 45.2 39.2 37.0 30.6 30.2 43.3 40.3 41.3 39.7 36.5 80.4 2.9 3.2 1.7 35.3 10.8 6.0 1.4 12.7 15.9 6.6 8.4 7.4 3.0 8.6 6.2 12.9 2.1 4.0 14.8 26.6 7.9 5.7 0.7 3.1 2.9 5.5 7.8 17.0 66.8 8.6 9.9 3.8 6.1 3.4 5.7 7.8 7.9 30.1 11.8 3.3 80.8 10.8 10.2 21.9 5.5 0.8 1.2 19.1 10.6 68.4 36.3 6.3 10.3 146.8 346.4 5.4 11.3 3.8 8.0 4.1 22.5 12.5 7.2 7.6 6.6 10.7 2.9 0.3 1.9 7.1 1.1 1.8 11.0 22.4 11.2 1.8 LRRIQ4 LRRC64 ENSG00000188306 "Leucine rich repeats and IQ motif containing 4" A6NIV6 3 169821922-169837775 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "testis: 2.9" "Group enriched" "Detected in some" 17 "Early spermatids: 42.8;Late spermatids: 27.0" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "RT4: 1.6;T-47d: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA036271, HPA036706" Uncertain Approved Mitochondria NA NA "Cluster 45: Intestine - Brush border" "Cluster 6: T47d - Mammary gland" "Cluster 29: Early spermatids - Spermatogenesis" Mitochondria "HPA036271: , HPA036706: AB_2675264" "unprognostic (5.09e-2)" "unprognostic (8.85e-2)" "unprognostic (2.55e-1)" "unprognostic (1.30e-4)" "unprognostic (5.26e-3)" "unprognostic (2.32e-2)" "unprognostic (2.04e-1)" "unprognostic (2.31e-1)" "unprognostic (1.29e-1)" "unprognostic (1.17e-1)" "unprognostic (9.72e-2)" "unprognostic (1.42e-1)" "unprognostic (2.12e-1)" "unprognostic (7.47e-2)" "unprognostic (1.55e-1)" "unprognostic (6.74e-2)" "unprognostic (4.56e-3)" 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 2.9 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.6 0.1 0.0 0.5 0.0 0.2 0.0 0.1 0.7 0.0 0.9 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.4 0.2 0.3 0.0 0.0 0.0 1.6 0.6 0.2 0.0 0.1 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 42.8 0.3 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.0 27.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 2.0 0.3 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 LRRN2 "FIGLER7, GAC1, LRANK1, LRRN5" ENSG00000170382 "Leucine rich repeat neuronal 2" O75325 1 204617170-204685738 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 22.2;Distal enterocytes: 18.1;Excitatory neurons: 57.8;Horizontal cells: 52.2;Inhibitory neurons: 40.0;Oligodendrocyte precursor cells: 39.2" "Group enriched" "Detected in many" 6 "breast cancer: 6.1;endometrial cancer: 10.6;glioma: 16.8;ovarian cancer: 18.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 9.3;NTERA-2: 18.0;RPMI-8226: 29.0;SuSa: 9.8;T-47d: 10.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029124 Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Endoplasmic reticulum" "HPA029124: AB_10601545" "unprognostic (2.16e-2)" "unprognostic (1.93e-1)" "unprognostic (1.35e-1)" "prognostic unfavorable (2.59e-7)" "unprognostic (1.40e-1)" "unprognostic (1.17e-1)" "unprognostic (2.89e-2)" "unprognostic (1.21e-1)" "unprognostic (4.63e-2)" "unprognostic (1.15e-1)" "unprognostic (1.52e-3)" "unprognostic (1.16e-2)" "unprognostic (1.68e-2)" "unprognostic (1.43e-2)" "unprognostic (7.33e-2)" "unprognostic (1.88e-1)" "unprognostic (1.59e-3)" 6.1 4.4 18.4 2.8 18.6 1.7 2.5 6.9 19.6 3.3 20.4 8.0 1.1 5.5 0.3 1.8 7.6 4.3 8.2 20.5 18.5 17.4 1.0 2.8 2.1 11.0 13.6 2.5 1.9 14.7 12.9 0.7 13.8 1.5 5.3 3.8 3.0 2.2 1.6 0.4 4.9 7.2 7.7 7.6 2.0 4.2 20.2 3.0 3.1 3.2 0.7 1.4 2.2 13.2 0.0 4.3 3.5 0.1 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.3 0.0 0.1 0.4 0.0 0.0 0.0 0.2 0.2 9.3 0.6 0.0 0.2 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.9 1.5 0.0 18.0 0.0 0.1 0.2 0.0 29.0 0.0 0.2 2.4 0.4 5.6 0.1 0.0 9.8 10.1 0.0 0.0 0.0 3.9 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.4 18.6 6.9 19.6 20.5 18.5 11.0 13.6 13.8 7.7 20.2 13.2 3.9 0.0 0.0 22.2 0.3 0.4 0.7 0.1 0.0 7.0 0.6 1.9 1.5 0.0 0.1 1.8 2.1 0.1 0.0 18.1 0.0 3.8 0.0 0.5 0.2 2.3 11.4 2.7 57.8 0.9 0.1 2.9 0.0 0.8 0.0 0.1 3.3 0.0 7.0 52.2 40.0 2.3 2.0 0.3 1.1 0.5 0.0 0.2 0.0 9.4 0.2 4.6 0.0 39.2 1.6 4.9 5.6 0.0 0.1 0.3 0.0 5.5 0.0 1.1 0.0 0.9 0.5 0.1 0.3 0.5 0.1 0.4 0.2 1.4 1.0 0.4 LSM10 MGC15749 ENSG00000181817 "LSM10, U7 small nuclear RNA associated" Q969L4 1 36391238-36397908 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048469 Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 57: B-cells - Immune response" Nucleoplasm "Nuclear bodies" "HPA048469: AB_2756307" "unprognostic (2.15e-2)" "unprognostic (4.10e-2)" "unprognostic (1.76e-1)" "unprognostic (2.64e-1)" "unprognostic (6.21e-2)" "unprognostic (2.14e-1)" "prognostic unfavorable (1.83e-4)" "unprognostic (1.22e-1)" "unprognostic (1.12e-1)" "unprognostic (1.90e-2)" "prognostic favorable (4.89e-4)" "unprognostic (1.04e-1)" "prognostic unfavorable (6.40e-6)" "unprognostic (1.84e-1)" "unprognostic (2.80e-1)" "unprognostic (3.59e-2)" "unprognostic (8.54e-2)" 39.2 32.7 53.1 32.0 54.2 23.9 32.8 54.5 67.5 31.9 55.0 62.3 20.1 36.3 30.4 26.8 31.6 22.7 72.9 53.4 58.7 42.3 51.7 30.6 52.3 54.4 55.2 31.7 30.5 36.9 41.8 18.0 55.3 40.8 17.7 9.7 29.1 30.5 165.0 30.1 36.7 27.9 55.2 55.3 38.7 28.9 57.8 27.2 31.0 110.3 47.6 42.8 28.2 54.3 54.6 81.2 29.9 80.7 68.9 67.2 31.0 47.9 69.4 75.1 57.1 36.4 50.6 127.4 64.5 65.0 55.6 29.3 51.2 62.1 49.5 87.1 61.2 64.1 47.1 87.1 83.8 49.0 90.3 56.8 54.4 67.6 47.6 40.7 77.8 71.7 60.2 60.5 53.4 96.3 54.8 55.5 77.5 67.0 83.3 40.9 28.8 86.3 73.6 32.6 38.1 28.7 38.7 49.4 120.6 47.9 25.5 41.3 52.2 34.0 47.3 90.0 76.0 79.5 115.7 102.4 68.4 73.9 78.7 240.2 264.1 340.1 125.3 266.4 139.0 386.4 125.1 132.0 189.4 388.0 112.1 120.7 346.4 111.6 256.4 243.9 172.3 301.8 53.1 54.2 54.5 67.5 53.4 58.7 54.4 55.2 55.3 55.2 57.8 54.3 27.8 12.8 14.4 3.9 82.2 32.2 37.2 53.3 13.1 17.4 40.9 44.4 55.9 21.5 30.4 46.0 6.2 56.1 58.5 23.4 140.8 40.7 9.7 18.6 32.7 31.7 28.2 40.2 8.6 47.1 58.8 36.8 19.4 23.3 41.2 25.7 32.2 66.8 105.7 18.5 9.1 23.4 63.1 77.0 89.3 32.9 38.8 67.6 51.6 7.5 72.0 41.0 66.9 3.5 6.7 47.4 35.3 47.0 67.0 40.3 47.7 106.4 12.4 14.3 13.1 28.4 38.8 7.8 23.4 27.7 40.1 40.0 51.0 43.3 28.5 27.3 LSR "ILDR3, LISCH7" ENSG00000105699 "Lipolysis stimulated lipoprotein receptor" Q86X29 19 35248330-35267964 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 144.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 335.6;Ductal cells: 260.5;Exocrine glandular cells: 278.9;Pancreatic endocrine cells: 336.0;Paneth cells: 273.6;Syncytiotrophoblasts: 248.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 500.5;CACO-2: 215.6;CAPAN-2: 225.3;HaCaT: 203.9;OE19: 300.4;RT4: 198.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007270, HPA075309" Approved Supported "Plasma membrane" NA NA 3500000 "Cluster 44: Non-specific - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "HPA007270: AB_1079253, HPA075309: " "unprognostic (3.90e-1)" "unprognostic (1.12e-1)" "unprognostic (2.34e-2)" "unprognostic (2.67e-3)" "unprognostic (2.28e-2)" "unprognostic (6.07e-3)" "unprognostic (1.55e-1)" "unprognostic (9.84e-2)" "unprognostic (2.17e-1)" "unprognostic (2.70e-2)" "unprognostic (2.23e-2)" "unprognostic (3.42e-2)" "prognostic favorable (8.09e-4)" "unprognostic (1.64e-1)" "unprognostic (1.84e-1)" "unprognostic (2.99e-2)" "unprognostic (1.54e-2)" 15.7 31.3 15.7 17.8 13.6 3.6 25.4 13.2 14.7 20.4 39.0 96.9 85.0 14.4 13.9 60.0 29.7 36.4 7.7 12.5 13.2 28.9 144.8 30.0 14.4 17.1 14.8 6.4 114.2 16.8 27.3 46.9 15.5 25.6 43.7 8.6 69.4 18.5 4.4 51.9 75.0 5.3 12.9 17.9 133.1 27.2 17.7 6.6 32.9 2.7 14.1 29.9 29.3 14.8 500.5 8.1 0.7 1.0 1.4 0.5 86.8 1.2 1.9 2.2 1.6 215.6 225.3 19.6 73.0 1.3 7.2 203.9 44.3 75.0 0.3 30.1 82.6 0.2 6.5 96.1 1.7 0.3 0.9 1.0 81.2 2.0 24.2 1.0 0.8 0.6 80.2 17.2 1.1 177.4 0.9 1.1 69.0 300.4 3.2 3.8 0.8 54.6 46.2 198.2 37.7 1.4 40.9 130.5 35.8 21.7 112.5 2.6 0.4 3.9 44.7 3.1 2.2 27.2 52.5 45.7 3.4 0.8 12.4 6.4 0.2 0.1 2.5 0.0 2.6 4.3 5.8 5.4 0.1 3.0 4.2 4.9 0.0 5.6 0.0 0.2 4.1 2.9 15.7 13.6 13.2 14.7 12.5 13.2 17.1 14.8 15.5 12.9 17.7 14.8 38.2 16.0 21.7 0.3 26.3 51.7 123.4 90.7 50.1 2.1 60.9 49.7 5.6 78.6 71.2 36.8 16.7 210.3 4.7 335.6 11.7 260.5 9.4 41.7 27.4 44.6 56.4 3.2 0.8 278.9 93.0 11.9 214.1 61.5 31.1 30.3 20.3 89.7 21.7 0.0 0.9 145.5 73.2 2.2 14.3 2.9 6.5 4.6 14.2 22.5 7.2 11.5 3.1 1.5 0.8 336.0 273.6 3.4 41.1 113.6 117.8 24.6 43.8 12.3 0.0 4.1 24.4 7.9 19.1 57.2 51.7 248.0 24.3 3.4 124.2 206.3 LST1 "B144, D6S49E, LST-1" ENSG00000204482 "Leukocyte specific transcript 1" O00453 6 31586124-31588909 "Predicted intracellular proteins, Predicted membrane proteins" "Cell shape, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "bone marrow: 100.3;lung: 48.8;lymphoid tissue: 181.9" "Group enriched" "Detected in many" 11 "Hofbauer cells: 407.1;Kupffer cells: 1326.9;Langerhans cells: 1240.5;Macrophages: 871.6;monocytes: 1096.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 1746.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 39.3;HMC-1: 73.6;MOLT-4: 39.6;NB-4: 76.2;THP-1: 179.9;U-937: 92.9" "Low region specificity" "Detected in all" HPA079451 Supported "Plasma membrane,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane, Cytosol" "HPA079451: " "unprognostic (1.08e-2)" "prognostic favorable (7.89e-4)" "unprognostic (6.99e-2)" "unprognostic (4.16e-3)" "unprognostic (3.13e-1)" "unprognostic (3.92e-2)" "unprognostic (3.65e-1)" "unprognostic (7.06e-3)" "unprognostic (2.81e-3)" "unprognostic (2.12e-1)" "unprognostic (1.70e-1)" "unprognostic (1.28e-1)" "prognostic unfavorable (5.97e-5)" "unprognostic (1.47e-1)" "prognostic unfavorable (7.62e-4)" "unprognostic (1.03e-1)" "unprognostic (1.95e-1)" 15.2 10.2 4.3 22.0 4.3 100.3 7.9 4.6 7.2 5.6 5.0 7.9 7.1 3.7 1.4 5.5 6.6 3.1 7.6 4.6 5.5 10.8 14.4 48.8 13.8 6.1 4.9 3.0 4.7 0.9 6.1 4.7 6.6 8.9 3.0 0.5 6.9 2.3 2.1 7.8 15.0 5.1 5.4 181.9 5.7 1.8 5.2 15.1 4.6 1.9 7.1 9.1 5.1 6.0 0.3 0.6 0.0 0.8 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.2 2.5 0.6 0.0 0.0 0.5 0.3 0.4 0.3 12.9 0.0 39.3 0.0 0.0 0.7 29.3 73.6 0.0 0.3 0.1 1.2 0.3 0.9 0.8 0.1 0.2 0.0 0.0 39.6 76.2 0.1 0.0 0.0 18.4 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 179.9 0.3 0.0 0.4 0.0 0.2 0.1 0.0 5.9 0.0 92.9 0.0 112.2 419.7 681.6 9.4 1273.9 80.7 32.8 15.9 20.2 392.9 21.9 10.9 9.0 1133.0 21.6 1746.7 69.9 12.0 541.6 4.3 4.3 4.6 7.2 4.6 5.5 6.1 4.9 6.6 5.4 5.2 6.0 5.4 35.3 86.7 0.7 43.7 35.2 0.3 0.2 0.0 0.3 3.2 12.2 1.9 7.2 13.0 11.0 0.0 2.9 42.8 1.0 0.0 0.6 1.5 0.4 1.9 12.9 0.0 15.1 0.2 0.2 3.8 9.2 1.5 0.4 70.3 0.1 22.9 5.8 407.1 0.0 0.3 0.0 2.0 1326.9 1240.5 5.4 3.7 871.6 44.4 24.4 1096.6 0.7 60.8 0.5 0.1 0.1 1.1 1.2 4.7 1.0 0.0 3.8 11.0 0.2 26.3 2.2 2.8 2.4 4.6 0.4 28.3 5.3 43.6 0.0 0.4 0.3 LUZP4 "CT-8, CT28, HOM-TES-85" ENSG00000102021 "Leucine zipper protein 4" Q9P127 X 115289715-115307563 "Predicted intracellular proteins" "mRNA transport, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 82 "testis: 8.2" "Cell type enriched" "Detected in some" 4 "Spermatogonia: 35.2" "Cancer enriched" "Detected in some" 9 "testis cancer: 13.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046436, HPA051999" Enhanced NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "HPA046436: AB_10964168, HPA051999: AB_2681688" "unprognostic (1.84e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.3 35.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LY6G6C "C6orf24, G6c, NG24" ENSG00000204421 "Lymphocyte antigen 6 family member G6C" O95867 6 31718648-31721746 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "skin 1: 511.5" "Cell type enhanced" "Detected in some" "Early spermatids: 11.3;Late spermatids: 13.1;Suprabasal keratinocytes: 64.2;Syncytiotrophoblasts: 20.4" "Cancer enhanced" "Detected in many" "head and neck cancer: 20.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.5;CACO-2: 1.0;HaCaT: 2.0;MCF7: 3.2;OE19: 1.5;SuSa: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" "Cluster 28: BEWO - Transcription regulation" "Cluster 28: Keratinocytes - Keratinization" "unprognostic (1.21e-1)" "unprognostic (3.05e-2)" "unprognostic (1.68e-1)" "unprognostic (4.85e-3)" "unprognostic (2.59e-3)" "unprognostic (1.35e-1)" "unprognostic (9.03e-2)" "unprognostic (1.79e-1)" "unprognostic (4.13e-1)" "unprognostic (1.76e-3)" "unprognostic (2.85e-1)" "unprognostic (8.80e-7)" "unprognostic (1.33e-2)" "unprognostic (2.56e-1)" "unprognostic (6.09e-2)" "unprognostic (9.38e-2)" 1.1 0.1 0.1 0.2 0.4 0.0 15.8 0.1 0.4 13.0 0.1 0.3 0.0 0.4 0.2 47.6 1.5 0.0 0.5 0.2 0.1 0.2 0.4 0.6 0.0 0.1 0.1 0.6 0.2 0.1 0.3 7.6 0.1 0.5 0.1 0.1 12.0 0.0 1.6 511.5 0.2 0.1 0.1 0.6 0.5 1.9 0.1 1.2 0.6 0.0 12.1 0.3 31.0 0.2 0.4 0.1 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 1.0 0.3 0.1 0.0 0.1 0.0 2.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.2 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.1 0.4 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.6 0.0 0.0 0.3 0.1 4.7 0.7 0.5 0.6 0.0 3.5 2.0 0.1 0.0 0.1 0.0 0.0 7.5 0.0 2.3 0.0 0.1 11.3 1.3 1.3 0.6 0.0 0.0 0.0 0.0 1.2 0.7 0.0 3.0 0.0 0.3 0.0 0.0 0.7 0.0 0.0 2.0 0.0 0.0 0.7 13.1 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.5 0.0 0.0 2.1 0.2 0.0 0.9 0.0 0.0 0.4 0.5 0.0 0.1 6.1 64.2 20.4 0.2 0.1 2.0 3.2 LYG2 LYGH ENSG00000185674 "Lysozyme g2" Q86SG7 2 99242246-99255282 "Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.8;retina: 3.5;skin 1: 8.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 13.7;Cone photoreceptor cells: 14.6;Excitatory neurons: 19.6;Horizontal cells: 15.2;Inhibitory neurons: 17.5;Rod photoreceptor cells: 29.9" "Cancer enhanced" "Detected in some" "ovarian cancer: 0.9" "Region enriched" "Detected in some" 4 "cerebellum: 4.8" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "THP-1: 1.7;U-937: 2.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA039179 Uncertain "Secreted in other tissues" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 61: Skin - Cornification" "Cluster 32: U-937 - Innate immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA039179: AB_10794633" "unprognostic (5.12e-2)" "unprognostic (8.70e-3)" "unprognostic (6.29e-2)" "unprognostic (3.91e-2)" "unprognostic (1.47e-1)" "unprognostic (7.29e-2)" "unprognostic (1.86e-2)" "unprognostic (1.78e-2)" "unprognostic (1.90e-1)" "unprognostic (1.30e-2)" "unprognostic (1.30e-5)" "unprognostic (1.40e-3)" "unprognostic (1.08e-13)" "unprognostic (9.98e-2)" "unprognostic (1.44e-1)" "unprognostic (1.19e-2)" "unprognostic (9.24e-3)" 0.2 0.1 0.4 0.1 0.5 0.5 0.0 4.8 1.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.1 0.6 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.1 0.0 3.5 0.3 0.0 0.3 8.8 0.1 0.0 0.0 0.2 0.2 1.4 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.7 0.3 0.4 0.4 0.5 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.3 0.3 0.9 0.2 0.0 1.0 0.2 0.0 0.0 0.1 0.4 0.1 0.2 0.6 0.1 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 1.0 0.2 0.6 0.3 0.0 1.2 0.2 0.6 0.4 1.1 0.3 0.5 0.1 0.0 0.0 0.0 0.4 0.3 1.7 0.6 0.6 0.4 0.1 0.4 0.2 0.8 0.1 0.3 2.5 0.4 0.0 0.2 0.1 0.3 0.0 0.2 0.6 0.8 0.4 0.0 1.1 0.3 0.3 0.1 0.2 0.0 0.9 0.1 0.0 0.4 0.5 4.8 1.0 0.6 0.1 0.0 0.0 0.2 0.0 0.4 0.7 0.9 0.0 0.0 5.5 1.2 0.6 0.5 0.3 0.0 13.7 0.8 0.9 0.3 5.7 0.1 0.0 14.6 0.9 1.6 0.1 0.0 0.1 6.1 0.6 0.9 0.7 0.0 0.0 19.6 0.0 0.2 0.8 0.0 0.3 0.0 0.5 1.1 0.0 0.2 15.2 17.5 0.0 0.0 0.9 0.3 2.2 0.0 0.2 1.8 0.0 0.2 6.9 4.1 7.5 8.9 0.1 0.0 0.7 0.0 0.7 0.3 0.3 0.0 29.9 0.0 2.0 0.9 1.8 1.6 0.0 0.4 0.3 0.9 0.2 0.4 0.1 LYPD6 MGC52057 ENSG00000187123 "LY6/PLAUR domain containing 6" Q86Y78 2 149329985-149474138 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.0;placenta: 15.7" "Cell type enhanced" "Detected in many" "Astrocytes: 40.8;Early spermatids: 59.7;Inhibitory neurons: 65.9;Late spermatids: 230.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 37.6;fHDF/TERT166: 48.2;HBF TERT88: 25.0;LHCN-M2: 46.2;RT4: 39.9" "Low region specificity" "Detected in all" HPA042805 Enhanced Approved Cytosol "Secreted in other tissues" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "HPA042805: AB_10794159" "unprognostic (1.77e-1)" "unprognostic (1.01e-1)" "unprognostic (7.23e-3)" "unprognostic (1.64e-2)" "unprognostic (3.25e-1)" "unprognostic (6.49e-3)" "unprognostic (6.97e-3)" "unprognostic (1.72e-1)" "unprognostic (2.73e-2)" "prognostic favorable (3.59e-4)" "unprognostic (4.14e-3)" "unprognostic (6.75e-2)" "unprognostic (7.33e-4)" "unprognostic (1.39e-1)" "unprognostic (1.94e-1)" "unprognostic (1.09e-1)" "prognostic favorable (2.72e-4)" 1.4 0.3 8.0 0.6 4.6 0.0 9.3 4.5 5.5 0.9 1.2 1.5 1.7 2.1 0.1 0.5 1.6 11.1 0.6 4.7 9.8 2.0 0.3 0.2 0.2 6.8 24.0 0.6 1.9 1.4 0.3 15.7 6.7 1.4 2.5 7.0 0.2 1.3 0.1 0.6 1.4 2.9 5.6 0.6 3.9 6.8 16.1 0.3 0.2 0.1 1.3 2.6 0.4 4.2 0.2 0.0 6.8 37.6 0.0 0.1 0.5 15.0 6.6 18.9 11.7 0.2 3.0 0.0 0.8 48.2 9.1 3.8 5.3 0.1 25.0 0.0 1.7 0.1 9.6 0.0 0.2 0.0 0.0 0.0 0.4 0.0 11.0 0.4 0.3 0.0 0.0 0.0 46.2 6.7 0.0 3.6 5.4 3.2 4.3 0.0 20.1 0.0 2.3 39.9 1.5 6.7 10.1 11.2 1.2 12.2 1.5 0.8 0.0 0.4 5.7 0.5 8.2 0.0 0.0 0.0 3.5 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 4.6 4.5 5.5 4.7 9.8 6.8 24.0 6.7 5.6 16.1 4.2 0.1 0.0 0.0 40.8 0.0 0.1 0.6 1.0 1.2 2.7 11.7 6.6 0.4 10.0 2.0 0.0 0.0 0.0 0.0 0.4 3.9 2.6 59.7 1.7 0.4 0.9 0.0 0.0 0.3 0.9 0.2 1.4 10.7 2.5 0.0 0.7 0.4 0.0 0.3 0.0 65.9 2.8 0.0 0.0 0.0 230.4 3.1 0.0 0.0 1.0 0.0 4.1 0.0 13.6 1.0 4.5 0.4 0.4 0.1 2.1 1.7 0.0 0.8 3.4 0.0 0.1 0.2 1.0 5.2 0.7 0.0 0.3 0.1 0.0 2.0 1.7 LYRM4 "C6orf149, CGI-203, ISD11" ENSG00000214113 "LYR motif containing 4" Q9HD34 6 5103629-5260950 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA030362 Approved Supported "Nuclear bodies" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 32: Non-specific - Translation" "Nuclear bodies" "HPA030362: AB_10601546" "unprognostic (2.41e-2)" "unprognostic (3.72e-2)" "unprognostic (7.68e-2)" "unprognostic (8.58e-2)" "unprognostic (1.30e-1)" "unprognostic (8.73e-2)" "unprognostic (1.85e-3)" "unprognostic (4.58e-2)" "unprognostic (7.83e-2)" "unprognostic (2.11e-1)" "unprognostic (1.03e-1)" "unprognostic (2.26e-1)" "unprognostic (2.79e-3)" "unprognostic (1.43e-1)" "unprognostic (2.76e-1)" "unprognostic (9.80e-2)" "unprognostic (5.23e-1)" 16.9 18.8 22.8 14.6 22.5 19.0 19.0 21.4 31.0 16.2 24.0 14.7 7.7 18.1 18.1 13.4 19.1 11.2 20.5 22.3 22.1 14.5 13.6 12.1 22.9 22.7 21.7 27.1 19.4 15.9 20.4 14.2 22.3 12.3 16.2 15.9 13.0 10.2 14.4 17.1 10.4 16.6 22.3 15.9 14.1 16.0 21.8 20.8 19.5 11.0 21.8 16.9 14.2 24.1 28.9 27.4 41.1 32.0 41.3 60.1 37.1 27.1 44.0 36.9 38.0 57.8 19.2 44.7 51.7 35.8 51.6 25.4 58.9 34.2 41.0 79.4 45.9 19.7 20.9 77.4 25.9 52.2 19.2 47.9 53.1 33.1 43.3 34.9 35.8 42.4 64.3 15.2 32.1 15.6 49.6 70.5 39.6 45.9 42.1 49.2 30.8 82.2 38.6 23.4 55.2 35.6 23.8 14.6 65.5 58.6 39.8 44.7 29.5 39.2 26.3 32.9 44.8 22.4 82.4 42.7 19.0 36.6 54.2 1.9 18.8 2.1 11.7 19.8 15.6 31.3 17.5 13.3 34.4 26.2 26.6 24.6 4.3 23.6 17.5 23.0 19.1 17.6 22.8 22.5 21.4 31.0 22.3 22.1 22.7 21.7 22.3 22.3 21.8 24.1 75.6 25.6 16.2 28.4 45.0 73.5 55.6 80.9 25.0 16.4 51.9 48.4 29.1 28.6 33.9 18.4 8.4 49.5 23.0 12.3 31.3 44.1 38.8 26.0 29.3 40.3 32.3 32.0 103.4 43.8 72.2 37.6 11.2 19.0 41.3 39.6 41.7 35.9 65.2 11.8 57.4 26.5 32.6 46.8 93.0 91.7 46.3 31.7 69.4 32.8 74.2 45.1 23.7 80.4 50.8 34.1 15.3 35.3 32.6 108.9 7.2 90.0 26.6 16.8 32.9 32.2 34.8 79.4 78.7 32.1 82.8 47.2 29.5 43.9 38.6 63.5 LZIC MGC15436 ENSG00000162441 "Leucine zipper and CTNNBIP1 domain containing" Q8WZA0 1 9922113-9943407 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 304.7;Spermatocytes: 191.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028184, HPA058614" Approved Approved Nucleoplasm,Cytosol NA NA 160000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm Cytosol "HPA028184: AB_10602706, HPA058614: AB_2683779" "unprognostic (1.56e-1)" "unprognostic (2.41e-1)" "unprognostic (1.76e-2)" "unprognostic (1.62e-1)" "unprognostic (6.26e-2)" "unprognostic (8.37e-2)" "prognostic unfavorable (2.47e-5)" "unprognostic (2.89e-1)" "unprognostic (3.79e-3)" "unprognostic (7.84e-2)" "unprognostic (1.70e-3)" "unprognostic (1.23e-1)" "prognostic favorable (3.56e-5)" "unprognostic (1.19e-1)" "unprognostic (3.76e-3)" "unprognostic (1.50e-2)" "unprognostic (1.95e-2)" 20.6 18.1 20.2 18.8 24.4 19.4 25.5 24.8 23.4 24.3 16.2 28.5 29.0 25.9 16.2 22.9 23.7 18.1 29.6 19.8 21.2 28.9 30.4 17.0 21.9 24.0 24.1 35.0 13.4 29.2 12.3 22.3 24.2 21.9 27.6 25.9 20.9 19.8 27.3 20.1 27.1 24.8 24.2 15.8 16.7 66.9 21.6 30.0 24.6 27.5 23.8 18.1 15.3 28.4 43.0 27.8 52.5 37.2 32.0 51.9 23.3 38.1 32.1 52.8 50.9 34.6 73.4 51.6 42.3 48.1 33.3 31.9 49.7 55.1 78.7 48.5 33.5 75.7 34.9 57.9 30.7 69.7 37.5 34.3 77.0 74.1 69.2 37.6 41.8 67.4 95.6 28.7 49.1 30.5 57.3 33.8 26.6 53.7 44.5 60.7 69.4 41.9 28.5 19.2 26.1 41.2 46.6 20.2 91.2 49.9 33.5 35.1 38.6 36.5 49.6 52.4 40.8 23.2 57.5 87.4 37.3 101.7 49.6 34.9 25.1 40.3 20.5 29.5 17.8 18.4 20.6 20.1 24.8 20.4 20.1 21.2 25.6 23.2 33.2 38.0 29.3 17.5 20.2 24.4 24.8 23.4 19.8 21.2 24.0 24.1 24.2 24.2 21.6 28.4 34.3 6.4 17.3 6.8 20.7 12.7 21.9 24.1 17.6 12.0 22.6 27.3 57.4 10.0 15.9 7.3 6.2 26.9 26.9 25.9 49.0 27.0 304.7 34.7 36.4 19.9 9.1 24.0 11.1 21.2 45.7 27.8 13.3 27.0 30.4 27.2 14.3 23.9 42.7 42.1 14.8 18.1 10.2 22.6 15.7 91.6 26.4 34.9 14.2 14.0 36.8 45.6 20.6 13.6 23.8 22.6 27.8 27.4 22.4 27.6 41.7 53.0 27.4 18.0 19.7 26.6 31.1 191.3 86.2 29.2 16.8 34.5 26.8 21.4 22.5 21.6 MAFF hMafF ENSG00000185022 "MAF bZIP transcription factor F" Q9ULX9 22 38200767-38216507 "Predicted intracellular proteins, Transcription factors" "Stress response, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 682.0;Syncytiotrophoblasts: 479.1;Urothelial cells: 409.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 23.9;neutrophil: 8.7;NK-cell: 21.1" "Group enriched" "Detected in many" 6 "granulocytes: 23.9;NK-cells: 21.1" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 79.2;SK-MEL-30: 104.9" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 5.6" "CAB025341, HPA055371" Approved Approved Nucleoplasm,Mitochondria No No "Cluster 10: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 44: Endometrium - Transcription" Nucleoplasm Mitochondria "CAB025341: , HPA055371: AB_2682797" "prognostic favorable (4.32e-4)" "unprognostic (2.54e-1)" "unprognostic (1.07e-1)" "unprognostic (2.67e-1)" "unprognostic (1.99e-2)" "unprognostic (2.13e-3)" "unprognostic (5.06e-3)" "unprognostic (3.42e-3)" "unprognostic (7.83e-3)" "unprognostic (5.36e-3)" "unprognostic (1.23e-3)" "unprognostic (2.44e-1)" "unprognostic (3.24e-2)" "unprognostic (2.84e-1)" "unprognostic (4.08e-2)" "unprognostic (1.07e-1)" "unprognostic (2.68e-2)" 102.9 22.8 9.4 12.9 9.0 36.2 69.9 9.3 10.7 37.4 9.4 26.6 8.1 28.8 2.1 53.4 64.2 41.4 53.8 8.2 11.9 32.0 30.8 59.2 4.7 14.5 10.0 53.9 19.7 5.3 19.5 34.5 13.4 39.5 10.3 19.6 28.6 5.5 73.3 45.7 19.6 23.2 10.5 9.3 45.4 3.0 14.1 7.4 25.0 6.9 11.3 53.8 41.4 16.6 20.8 3.3 4.4 6.6 6.9 21.3 20.6 41.4 54.2 19.8 21.0 6.1 16.0 0.7 3.9 16.9 29.5 13.5 1.1 15.7 33.2 3.9 0.6 2.1 2.1 5.2 18.0 1.3 7.1 9.3 25.7 79.2 43.6 17.6 42.1 1.9 4.2 18.6 15.6 4.9 0.8 5.2 3.3 22.0 16.8 1.4 3.8 4.3 19.9 30.6 2.2 3.7 6.1 15.4 104.9 10.7 3.3 1.5 57.9 24.7 19.2 18.8 13.7 7.2 8.0 0.7 37.4 1.4 15.9 23.9 0.4 0.3 2.9 0.7 2.8 0.8 1.7 2.1 1.4 0.5 2.1 1.6 8.7 21.1 3.5 0.2 0.7 1.8 9.4 9.0 9.3 10.7 8.2 11.9 14.5 10.0 13.4 10.5 14.1 16.6 215.4 54.5 43.4 1.0 19.3 125.9 344.1 56.8 169.0 2.9 302.9 214.1 18.6 67.2 49.5 11.0 0.0 37.8 112.5 134.2 7.9 49.9 0.5 284.7 149.3 97.3 104.8 5.7 0.8 24.2 77.5 134.7 132.5 682.0 22.2 11.5 22.1 8.2 26.0 0.0 1.6 112.5 34.6 14.0 131.1 0.4 9.9 113.5 58.7 1.0 10.2 36.0 17.5 1.5 1.3 76.0 181.0 3.8 25.8 258.4 67.6 3.7 37.9 3.6 19.7 265.2 153.1 2.4 1.0 139.5 103.1 479.1 59.0 8.4 75.5 409.2 MAGEA12 "CT1.12, MAGE12" ENSG00000213401 "MAGE family member A12" P43365 X 152733757-152737669 "Predicted intracellular proteins" "Tumor antigen" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "testis: 2.8" "Group enriched" "Detected in some" 16 "Spermatocytes: 9.4;Spermatogonia: 20.2" "Cancer enhanced" "Detected in many" "melanoma: 10.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 143.0;HMC-1: 57.8;K-562: 89.5;OE19: 112.7;SH-SY5Y: 48.2;U-2 OS: 87.2;U-266/70: 69.2" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 21: OE19 - Mitochondria" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "unprognostic (3.47e-2)" "unprognostic (4.54e-1)" "prognostic unfavorable (3.22e-4)" "unprognostic (1.82e-1)" "unprognostic (3.25e-1)" "unprognostic (1.60e-3)" "unprognostic (8.57e-4)" "unprognostic (4.61e-2)" "unprognostic (1.78e-1)" "unprognostic (4.06e-2)" 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.4 0.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 2.8 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.3 0.0 5.1 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 143.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.2 0.0 0.0 0.0 57.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 89.5 0.0 0.0 0.0 0.0 0.0 0.0 112.7 41.6 0.1 0.0 1.1 0.0 0.1 3.3 48.2 0.0 24.3 13.3 0.0 0.7 0.2 0.4 0.1 87.2 12.7 6.5 69.2 0.1 0.1 0.2 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.4 0.7 0.4 0.4 0.4 0.4 0.4 0.3 0.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 9.4 20.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MAGEA4 "CT1.4, MAGE-41, MAGE-X2, MAGE4, MAGE4A, MAGE4B, MGC21336" ENSG00000147381 "MAGE family member A4" P43358 X 151912509-151925170 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Tumor antigen" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 23.6" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 20.2;Spermatocytes: 48.7;Spermatogonia: 179.8;Syncytiotrophoblasts: 33.0" "Cancer enhanced" "Detected in many" "lung cancer: 19.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 440.0;AN3-CA: 263.1;HMC-1: 496.1;U-266/84: 836.2" "HPA021942, CAB040535" Enhanced Approved "Nuclear speckles,Cytosol" NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 16: U-266 - Nucleosome" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Nuclear speckles" Cytosol "CAB040535: , HPA021942: AB_1853490" "unprognostic (7.90e-3)" "unprognostic (6.66e-3)" "unprognostic (5.39e-1)" "unprognostic (1.36e-1)" "unprognostic (5.81e-2)" "unprognostic (2.94e-2)" "unprognostic (4.10e-1)" 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 23.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 440.0 0.0 0.0 263.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.5 0.0 0.1 0.6 0.0 0.0 0.0 0.8 0.0 0.0 0.3 0.1 0.0 0.0 496.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.8 0.0 0.0 0.4 0.0 0.2 0.0 0.3 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.9 0.1 0.2 4.1 0.0 0.5 132.0 0.0 2.4 105.9 836.2 0.7 0.6 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 20.2 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 14.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 4.6 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 48.7 179.8 0.0 0.0 33.0 0.0 0.0 0.0 0.0 MAGEA6 "CT1.6, MAGE-3b, MAGE3B, MAGE6" ENSG00000197172 "MAGE family member A6" P43360 X 152766136-152769747 "Cancer-related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Tumor antigen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 22 "testis: 7.1" "Group enriched" "Detected in some" 5 "Spermatocytes: 29.8;Spermatogonia: 49.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 210.0;HMC-1: 156.5;K-562: 136.8;OE19: 272.9;PC-3: 148.1;SK-BR-3: 138.3;U-266/70: 176.3;U-266/84: 119.7" NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 21: OE19 - Mitochondria" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "unprognostic (3.09e-1)" "unprognostic (5.94e-2)" "unprognostic (3.77e-2)" "prognostic unfavorable (1.93e-4)" "unprognostic (3.50e-2)" "unprognostic (1.74e-1)" "unprognostic (5.33e-2)" "unprognostic (8.33e-2)" "unprognostic (6.00e-2)" 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 17.6 0.0 0.3 0.0 0.0 37.4 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 210.0 0.1 0.0 0.0 0.0 0.1 0.0 1.0 50.8 1.1 0.0 0.0 156.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 136.8 75.4 0.0 0.2 0.4 0.0 0.2 272.9 148.1 0.1 0.0 8.5 0.0 0.0 7.8 58.3 0.0 138.3 20.2 0.1 2.2 10.1 0.7 64.2 100.7 3.7 19.9 176.3 119.7 0.2 1.2 0.0 77.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.1 29.8 49.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 MAGEB1 "CT3.1, DAM10, MAGE-Xp, MAGEL1, MGC9322" ENSG00000214107 "MAGE family member B1" P43366 X 30243730-30252040 "Predicted intracellular proteins" "Tumor antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 29 "testis: 15.5" "Group enriched" "Detected in some" 9 "Spermatocytes: 14.2;Spermatogonia: 14.6" "Cancer enriched" "Detected in some" 9 "testis cancer: 7.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 70 "K-562: 25.1;U-266/70: 53.8;U-266/84: 40.5" "HPA001193, HPA002820" Enhanced NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "HPA001193: AB_1079296, HPA002820: AB_1079295" "unprognostic (1.26e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 53.8 40.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.2 14.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MAGEB16 ENSG00000189023 "MAGE family member B16" A2A368 X 35798342-35803735 "Predicted intracellular proteins" "Tumor antigen" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 33 "testis: 3.3" "Group enriched" "Detected in some" 35 "Spermatocytes: 7.4;Spermatogonia: 13.8" "Cancer enhanced" "Detected in single" "testis cancer: 0.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "U-266/70: 59.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA055743, HPA076456" Uncertain Approved Nucleoplasm,Centrosome NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Nucleoplasm Centrosome "HPA055743: AB_2682902, HPA076456: " "unprognostic (2.12e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 59.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 7.4 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MAGEB3 CT3.5 ENSG00000198798 "MAGE family member B3" O15480 X 30230436-30237492 "Predicted intracellular proteins" "Tumor antigen" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 114 "epididymis: 17.7;testis: 5.1" "Group enriched" "Detected in some" 8 "Spermatocytes: 13.0;Spermatogonia: 6.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "SuSa: 1.3;U-266/70: 2.1" "Not detected" "Not detected" HPA072203 Approved NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA072203: AB_2686492" "unprognostic (3.34e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.0 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MAGEB4 "CT3.6, MGC33144" ENSG00000120289 "MAGE family member B4" O15481 X 30242000-30244187 "Predicted intracellular proteins" "Tumor antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 100 "epididymis: 27.2;testis: 8.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA030456 Enhanced NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 31: Spermatids - Spermatogenesis" "HPA030456: AB_10602707" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MAGED1 "DLXIN-1, NRAGE" ENSG00000179222 "MAGE family member D1" Q9Y5V3 X 51803007-51902354 "Cancer-related genes, Predicted intracellular proteins" "Biological rhythms, Ubl conjugation pathway" "Tumor antigen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 335.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 534.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043645 Approved Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol "HPA043645: AB_2678597" "unprognostic (5.70e-2)" "unprognostic (1.16e-1)" "unprognostic (7.29e-2)" "unprognostic (1.39e-2)" "unprognostic (3.92e-2)" "unprognostic (1.37e-1)" "unprognostic (4.04e-3)" "unprognostic (2.04e-2)" "unprognostic (3.92e-1)" "unprognostic (1.77e-1)" "unprognostic (3.15e-3)" "unprognostic (1.42e-1)" "unprognostic (6.10e-3)" "unprognostic (2.14e-3)" "unprognostic (2.22e-1)" "prognostic unfavorable (3.25e-4)" "unprognostic (1.71e-3)" 32.4 125.4 69.8 37.7 73.1 16.7 38.0 34.7 71.1 99.7 99.2 40.0 32.4 57.3 102.4 26.6 64.7 58.8 70.2 70.7 108.8 43.0 71.5 40.4 29.2 57.4 66.2 62.5 80.2 76.8 157.0 116.2 76.3 71.7 39.6 37.1 85.3 89.0 46.8 29.9 32.3 77.6 62.0 35.4 54.6 56.5 84.7 49.0 73.7 39.1 31.6 45.4 35.5 49.7 21.3 76.2 238.5 205.8 184.3 330.4 128.1 281.2 357.7 152.5 240.0 157.3 71.0 29.9 53.6 534.9 54.4 15.6 215.5 99.6 113.2 31.8 83.1 20.3 0.4 205.7 140.9 75.8 35.8 312.2 35.0 128.6 29.1 267.7 184.8 77.1 31.5 57.6 310.5 194.8 87.7 25.4 187.6 69.4 154.3 88.4 154.2 4.1 156.7 37.4 60.9 340.1 0.0 80.6 41.9 232.0 145.6 18.8 185.6 66.1 166.5 234.7 31.8 37.5 59.5 60.3 257.9 6.9 175.1 1.5 4.4 3.1 21.1 6.0 18.7 17.2 13.7 18.5 13.2 19.4 17.1 20.5 1.3 16.3 6.1 55.8 21.1 14.3 69.8 73.1 34.7 71.1 70.7 108.8 57.4 66.2 76.3 62.0 84.7 49.7 12.2 76.9 34.5 85.8 17.1 11.5 20.4 48.1 12.5 33.2 41.9 27.9 53.4 32.9 63.8 35.0 8.4 335.2 17.1 18.6 29.4 47.9 2.5 35.6 73.4 24.5 57.1 13.9 97.5 49.9 171.5 69.5 34.7 54.3 17.7 60.7 39.7 62.5 114.6 45.4 138.5 74.4 54.9 9.2 6.8 10.0 43.2 6.3 24.9 42.2 4.9 39.7 13.4 101.6 55.0 33.5 13.5 57.6 72.6 20.2 15.9 33.2 48.3 12.5 13.1 28.2 50.0 5.7 5.9 12.4 8.2 185.7 11.9 169.9 25.2 18.8 MAGI3 MAGI-3 ENSG00000081026 "Membrane associated guanylate kinase, WW and PDZ domain containing 3" Q5TCQ9 1 113390515-113685923 "Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 34.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 266.0;Excitatory neurons: 206.7;Oligodendrocyte precursor cells: 128.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008444 Supported "Cell Junctions" NA NA "Cluster 77: Retina - Visual perception" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Cell Junctions" "HPA008444: AB_2668069" "unprognostic (4.07e-1)" "unprognostic (3.59e-2)" "unprognostic (1.54e-3)" "unprognostic (2.32e-2)" "unprognostic (2.31e-2)" "unprognostic (5.21e-3)" "unprognostic (2.23e-1)" "unprognostic (7.06e-2)" "unprognostic (2.80e-2)" "prognostic favorable (4.29e-4)" "unprognostic (1.09e-2)" "unprognostic (1.03e-1)" "prognostic favorable (2.60e-8)" "unprognostic (1.71e-2)" "unprognostic (7.85e-2)" "unprognostic (2.65e-1)" "unprognostic (1.50e-2)" 2.8 3.3 5.4 2.3 7.1 0.2 7.6 2.8 8.6 3.5 2.8 9.2 5.9 4.9 6.5 7.6 3.7 3.8 3.2 5.4 5.4 7.1 6.2 13.2 1.2 4.0 7.4 6.0 10.7 3.9 4.7 7.4 6.6 4.2 8.2 34.8 4.3 2.6 1.5 1.9 7.5 4.6 2.0 2.3 11.6 4.1 5.2 2.4 10.9 2.4 3.8 2.7 4.0 5.9 8.8 10.8 10.0 4.5 4.4 6.4 2.7 6.1 3.0 4.8 5.3 9.5 2.6 0.4 4.5 5.7 4.1 3.9 9.1 4.7 5.9 9.5 8.6 4.0 9.6 4.3 1.0 3.3 5.6 3.4 2.3 5.1 11.0 5.7 6.7 4.2 4.7 8.4 6.6 5.9 5.2 0.9 3.5 15.3 6.3 7.3 16.1 1.0 5.5 4.0 8.9 9.0 7.4 12.1 2.2 12.3 6.3 1.7 11.6 7.8 9.8 7.1 8.7 3.1 2.8 0.0 4.1 1.5 6.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 5.4 7.1 2.8 8.6 5.4 5.4 4.0 7.4 6.6 2.0 5.2 5.9 14.0 266.0 103.2 106.7 1.3 10.8 9.1 9.2 21.1 97.1 27.1 16.0 9.2 14.3 60.7 12.9 50.1 16.0 1.0 51.8 7.9 10.9 39.4 11.2 19.7 11.9 13.8 3.2 206.7 10.7 2.4 14.9 37.8 15.9 6.3 12.1 12.1 14.4 4.1 40.4 100.1 23.6 4.1 2.2 6.9 28.4 10.2 2.6 12.4 92.8 0.5 35.6 0.0 128.7 17.7 13.5 40.2 11.3 8.8 9.5 32.6 5.3 17.5 45.6 13.1 13.4 10.7 23.8 9.6 23.4 7.5 5.5 4.1 8.7 28.9 10.5 MAJIN C11orf85 ENSG00000168070 "Membrane anchored junction protein" Q3KP22 11 64937517-64972108 "Predicted intracellular proteins" Meiosis DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 22.5" "Group enriched" "Detected in some" 8 "Distal tubular cells: 3.9;Proximal tubular cells: 9.5" "Cancer enhanced" "Detected in some" "cervical cancer: 1.0" "Region enriched" "Detected in single" 4 "cerebellum: 2.6" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.3" "Lineage enriched" "Detected in single" 5 "B-cells: 1.3" "Group enriched" "Detected in some" 10 "CAPAN-2: 7.5;SiHa: 3.5" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 83: Testis - Spermatogenesis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (3.37e-1)" "unprognostic (6.43e-3)" "unprognostic (3.69e-2)" "unprognostic (7.05e-2)" "unprognostic (9.64e-3)" "unprognostic (2.92e-2)" "unprognostic (4.46e-2)" "unprognostic (1.06e-1)" "unprognostic (9.11e-2)" "unprognostic (4.11e-2)" "unprognostic (1.61e-2)" "unprognostic (2.58e-1)" "unprognostic (1.48e-2)" "unprognostic (2.43e-1)" "unprognostic (2.79e-1)" "unprognostic (4.18e-3)" "unprognostic (1.76e-2)" 0.0 0.2 0.2 0.2 0.6 0.1 0.2 2.6 0.6 0.1 0.0 0.1 0.0 0.0 2.0 0.1 1.1 2.9 0.0 0.1 0.1 1.4 1.2 0.2 1.4 0.5 0.2 0.0 0.3 0.0 0.0 0.1 0.3 0.3 0.2 0.2 0.1 0.6 0.0 1.2 0.4 0.0 0.2 0.6 0.2 22.5 0.1 0.1 0.9 0.0 1.3 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 7.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.2 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 2.6 0.6 0.1 0.1 0.5 0.2 0.3 0.2 0.1 0.4 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.3 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 MAMLD1 "CG1, CXorf6, F18" ENSG00000013619 "Mastermind like domain containing 1" Q13495 X 150361422-150514178 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 33.0;Excitatory neurons: 27.5;Leydig cells: 33.8;Oligodendrocyte precursor cells: 81.4;Peritubular cells: 24.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+ RasG12V: 23.3;U-2197: 36.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003923 Uncertain Supported Nucleoplasm NA NA "Cluster 37: B-cells - Transcription" "Cluster 43: Testis - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm "HPA003923: AB_10602034" "unprognostic (4.18e-3)" "unprognostic (1.74e-1)" "unprognostic (1.63e-1)" "unprognostic (4.29e-2)" "unprognostic (4.16e-2)" "unprognostic (5.09e-2)" "unprognostic (2.31e-1)" "unprognostic (7.68e-2)" "unprognostic (2.08e-2)" "unprognostic (9.74e-2)" "unprognostic (9.86e-3)" "unprognostic (4.82e-2)" "unprognostic (1.86e-1)" "unprognostic (3.33e-2)" "unprognostic (3.58e-2)" "unprognostic (1.41e-3)" "unprognostic (9.76e-3)" 4.7 2.6 4.9 1.4 5.6 1.6 3.4 0.1 4.6 4.2 0.0 3.1 0.9 5.3 2.2 1.7 5.0 2.4 2.0 4.3 9.3 1.9 1.7 4.8 1.6 1.8 1.3 12.9 3.1 2.0 4.3 1.7 4.4 3.1 1.1 2.9 1.8 6.6 4.5 1.8 1.3 3.1 1.0 1.4 1.9 10.3 11.1 0.8 1.1 1.9 1.0 3.7 2.3 0.1 7.3 2.9 3.8 7.6 10.9 4.1 0.0 6.8 14.3 10.3 23.3 0.0 0.4 0.0 3.4 16.3 8.1 0.2 4.2 3.2 14.0 10.4 0.3 0.1 8.8 0.2 8.1 0.4 0.0 5.6 0.6 11.7 1.4 5.2 2.2 0.6 0.2 0.0 9.9 1.4 0.0 0.1 0.7 0.0 5.4 0.5 14.7 0.4 1.7 0.1 0.9 0.8 2.4 0.2 3.8 0.9 0.2 0.1 2.8 5.5 6.9 36.8 12.2 0.4 0.5 0.2 15.2 2.9 7.6 0.0 0.0 0.0 0.2 0.0 0.3 0.6 0.4 0.3 0.0 0.2 0.3 0.7 0.1 0.1 0.0 0.0 0.5 0.2 4.9 5.6 0.1 4.6 4.3 9.3 1.8 1.3 4.4 1.0 11.1 0.1 3.3 0.0 0.5 33.0 0.4 3.4 0.9 1.2 0.0 1.5 1.9 0.9 1.9 5.7 0.2 0.0 10.4 0.0 0.1 0.0 1.9 3.2 1.1 1.4 5.2 5.5 3.6 3.2 27.5 2.5 0.0 4.8 0.0 3.3 0.0 5.4 4.6 4.8 0.5 13.5 18.3 0.6 0.0 0.8 20.5 4.6 33.8 2.3 3.6 11.2 0.6 2.2 0.0 81.4 5.0 2.2 0.1 24.0 0.3 3.1 0.0 0.4 0.1 0.6 6.6 2.8 3.4 0.3 0.4 0.2 4.1 0.0 1.9 8.3 0.0 0.4 MANSC4 ENSG00000205693 "MANSC domain containing 4" A6NHS7 12 27762427-27780236 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "testis: 1.5" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 2.1;Oligodendrocyte precursor cells: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA039454, HPA039682" Uncertain NA NA "Cluster 34: Basophils - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 47: Cytotrophoblasts - Unknown function" "HPA039454: AB_2676515, HPA039682: AB_10805483" "unprognostic (1.13e-1)" "unprognostic (4.74e-2)" "unprognostic (2.34e-2)" "unprognostic (2.75e-2)" "unprognostic (6.07e-2)" "unprognostic (1.09e-1)" "unprognostic (1.18e-1)" "unprognostic (2.25e-4)" "unprognostic (1.96e-1)" "unprognostic (2.49e-2)" "unprognostic (2.87e-3)" "unprognostic (2.50e-3)" "unprognostic (7.15e-3)" "unprognostic (2.34e-1)" "unprognostic (1.00e-2)" "unprognostic (1.21e-1)" "unprognostic (2.10e-2)" 0.1 0.0 0.2 0.1 0.1 0.2 0.1 0.6 0.3 0.1 0.1 0.1 0.1 0.2 0.2 0.0 0.1 0.0 0.0 0.2 0.2 0.4 0.0 0.2 0.5 0.3 0.1 0.2 0.2 0.0 0.7 0.5 0.1 0.1 0.0 0.5 0.0 0.1 0.1 0.2 0.1 0.0 0.0 0.1 0.1 1.5 0.3 0.1 0.1 0.1 0.3 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.6 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.2 0.2 0.1 0.5 0.1 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.6 0.3 0.2 0.2 0.3 0.1 0.1 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.7 0.0 0.2 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 MAP1S "BPY2IP1, C19orf5, FLJ10669, MAP8, VCY2IP1" ENSG00000130479 "Microtubule associated protein 1S" Q66K74 19 17719242-17734513 "Predicted intracellular proteins" Apoptosis DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 82.9" "Group enriched" "Detected in all" 4 "Early spermatids: 98.1;Late spermatids: 293.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050934, HPA054637" Approved Supported "Nucleoplasm,Nucleoli,Cell Junctions,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 78: Testis - Spermatogenesis" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "Nucleoplasm, Nucleoli, Cell Junctions" "HPA050934: AB_2681281, HPA054637: AB_2682552" "unprognostic (8.47e-2)" "unprognostic (2.39e-2)" "unprognostic (1.60e-1)" "unprognostic (2.72e-1)" "unprognostic (3.70e-1)" "unprognostic (8.23e-2)" "prognostic unfavorable (5.29e-4)" "unprognostic (2.53e-1)" "unprognostic (6.17e-2)" "unprognostic (4.39e-2)" "prognostic favorable (2.65e-4)" "unprognostic (6.33e-2)" "unprognostic (1.19e-1)" "unprognostic (1.36e-1)" "unprognostic (1.72e-1)" "unprognostic (2.09e-1)" "unprognostic (8.65e-2)" 20.5 13.9 48.2 8.7 51.9 11.2 19.1 36.8 82.9 18.9 30.1 21.5 7.7 24.8 5.4 11.9 19.2 7.9 18.8 51.4 40.5 15.4 12.4 23.5 9.0 44.7 41.1 21.6 15.6 5.4 22.0 9.7 43.3 17.4 2.4 2.8 19.7 6.5 32.4 12.2 17.7 3.6 39.2 18.3 20.1 74.7 40.6 6.1 16.1 5.4 3.9 21.6 14.6 47.7 30.1 43.2 12.4 16.9 10.4 15.4 34.0 18.3 8.8 10.9 12.3 61.3 16.0 17.3 33.8 11.4 12.8 15.3 10.5 14.5 4.6 21.8 61.1 15.1 36.3 39.2 22.1 16.8 20.9 16.7 8.3 16.7 10.5 7.9 22.6 12.5 24.2 9.5 6.0 39.0 20.8 42.0 28.7 17.1 50.8 33.3 10.2 17.5 14.8 43.4 23.0 26.5 10.7 14.8 18.9 9.0 9.9 17.8 37.3 19.7 18.2 40.7 27.2 18.1 23.3 17.4 23.7 26.7 25.1 18.5 22.6 25.9 15.7 22.2 15.1 15.7 12.3 15.6 25.9 15.5 10.1 13.9 31.4 13.0 17.9 21.2 12.2 19.0 48.2 51.9 36.8 82.9 51.4 40.5 44.7 41.1 43.3 39.2 40.6 47.7 11.1 3.2 7.5 4.2 14.7 10.3 14.0 13.1 13.1 11.1 12.3 8.6 5.5 15.7 12.1 3.7 8.4 21.7 14.0 30.9 3.9 22.2 98.1 12.9 11.5 18.5 20.4 3.8 8.4 17.2 16.9 12.3 19.4 26.9 10.2 12.0 20.7 4.8 26.1 40.4 5.5 16.6 12.2 18.7 25.1 293.2 22.4 20.7 1.8 2.8 17.4 8.1 8.2 4.5 7.1 24.2 15.8 31.6 8.8 14.9 19.0 5.9 6.2 6.3 13.1 7.7 13.0 25.9 21.4 5.4 3.3 33.8 11.3 8.1 18.3 13.7 MAP2K7 "Jnkk2, MKK7, PRKMK7" ENSG00000076984 "Mitogen-activated protein kinase kinase 7" O14733 19 7903843-7914478 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001633, CAB004262, HPA064711" Supported Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 59: Non-specific - Translation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" "Plasma membrane, Cytosol" "Golgi apparatus" "CAB004262: AB_627925, HPA001633: AB_1079516, HPA064711: AB_2685331" "unprognostic (1.77e-1)" "unprognostic (5.04e-2)" "unprognostic (1.06e-2)" "unprognostic (2.16e-1)" "unprognostic (4.24e-2)" "prognostic favorable (8.54e-5)" "unprognostic (1.80e-3)" "unprognostic (2.55e-1)" "unprognostic (2.69e-2)" "unprognostic (1.69e-2)" "unprognostic (1.27e-3)" "unprognostic (1.56e-1)" "unprognostic (3.54e-2)" "unprognostic (3.71e-2)" "unprognostic (6.05e-2)" "unprognostic (1.73e-2)" "prognostic favorable (1.56e-4)" 19.1 17.0 17.9 11.7 17.8 19.4 19.5 16.8 19.0 25.1 10.4 24.4 13.1 26.1 3.7 20.2 20.5 5.9 20.8 14.8 15.2 18.7 24.7 17.1 11.7 17.3 17.3 23.2 21.6 9.6 23.4 9.2 17.1 21.0 4.6 5.6 19.2 7.9 52.4 27.9 20.1 6.2 15.1 24.5 18.8 17.5 17.3 10.9 19.0 16.4 6.1 22.0 22.4 19.9 25.8 14.4 12.2 20.2 9.7 9.3 22.8 16.5 8.0 11.0 11.3 20.9 15.2 30.5 25.9 8.8 10.7 22.9 10.7 12.8 4.3 24.7 53.3 21.4 20.9 15.6 12.4 20.1 26.0 10.8 16.1 8.7 9.8 14.5 10.0 21.9 31.9 38.5 6.5 13.4 28.8 48.6 21.7 13.6 32.0 28.5 13.4 31.0 9.8 21.0 22.4 22.5 11.3 19.4 23.9 7.3 21.0 22.7 15.3 33.2 19.0 23.7 22.7 55.5 27.7 28.8 16.6 29.2 13.6 0.0 0.8 0.6 0.6 0.8 0.4 0.7 0.5 0.6 0.4 1.0 0.5 0.7 1.5 1.0 0.5 0.8 0.2 0.4 17.9 17.8 16.8 19.0 14.8 15.2 17.3 17.3 17.1 15.1 17.3 19.9 15.4 25.6 18.1 11.1 27.0 38.6 37.2 22.7 22.2 52.9 23.5 16.5 14.4 24.3 14.5 20.2 77.2 28.3 27.8 31.1 13.7 22.8 4.8 16.2 20.3 19.5 36.5 23.6 9.9 19.0 31.1 18.5 16.3 24.8 10.8 33.3 21.4 22.2 18.6 57.2 11.0 24.0 32.6 22.2 17.1 11.7 28.9 20.5 32.0 6.5 25.3 23.9 46.4 9.0 15.0 25.7 20.8 12.4 30.4 39.8 38.7 18.4 15.3 65.7 32.9 30.2 22.1 17.7 36.4 22.7 42.6 49.3 30.3 30.3 27.6 33.2 MAP3K13 "LZK, MEKK13" ENSG00000073803 "Mitogen-activated protein kinase kinase kinase 13" O43283 3 185282941-185489094 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016497, HPA036691, HPA036692" Uncertain Approved "Nucleoplasm,Centriolar satellite,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 68: Epididymis - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 22: Epithelial cell types - Mixed function" "Centriolar satellite" "Nucleoplasm, Cytosol" "HPA016497: AB_10670027, HPA036691: AB_10673661, HPA036692: AB_10670845" "unprognostic (8.95e-2)" "unprognostic (6.72e-3)" "unprognostic (9.46e-2)" "prognostic unfavorable (1.28e-5)" "unprognostic (5.16e-2)" "unprognostic (2.81e-1)" "unprognostic (2.61e-1)" "unprognostic (1.23e-2)" "unprognostic (9.04e-2)" "prognostic favorable (1.11e-4)" "prognostic unfavorable (7.27e-5)" "unprognostic (2.70e-3)" "unprognostic (1.54e-2)" "unprognostic (2.94e-2)" "unprognostic (2.82e-1)" "unprognostic (6.64e-2)" "unprognostic (9.31e-3)" 14.7 34.0 18.5 13.0 19.8 15.8 21.0 23.2 25.8 17.0 18.5 24.6 24.3 17.9 56.8 19.7 20.2 18.1 10.4 19.7 20.4 30.9 29.6 17.5 11.7 20.7 21.7 22.2 25.9 34.6 20.7 13.1 21.1 19.7 26.2 36.2 26.2 14.9 4.7 14.0 25.0 17.0 21.2 13.1 23.9 18.8 21.5 11.1 25.7 6.8 15.0 23.2 15.8 23.5 73.9 14.5 27.4 0.7 24.4 29.9 16.1 16.5 11.2 26.2 31.5 27.9 27.0 0.6 55.1 30.4 43.7 41.1 0.8 38.4 46.5 82.1 36.8 0.3 18.9 23.3 26.5 39.2 20.1 27.2 32.8 22.6 28.1 27.1 29.6 0.7 0.9 57.5 23.8 23.0 4.6 18.2 31.5 56.5 33.4 0.6 32.8 40.5 46.9 18.8 44.7 29.8 28.0 41.5 59.9 29.8 62.8 21.5 19.7 21.5 27.8 39.4 36.5 29.3 40.8 24.4 31.4 19.5 36.1 14.0 21.6 9.4 16.6 22.1 25.7 42.8 19.6 21.0 37.4 34.9 27.2 26.6 35.9 20.8 15.9 16.4 8.6 12.4 18.5 19.8 23.2 25.8 19.7 20.4 20.7 21.7 21.1 21.2 21.5 23.5 69.5 54.5 82.7 80.0 41.8 141.6 219.1 196.7 100.7 117.9 144.0 115.1 25.2 144.4 131.6 79.1 91.8 139.5 22.9 96.1 287.6 106.6 134.8 76.5 50.7 65.9 106.4 43.8 170.7 127.5 38.9 49.0 72.4 73.1 29.8 96.6 93.5 99.4 64.9 45.4 184.5 130.9 138.4 53.2 193.0 213.0 43.2 52.7 85.4 28.1 283.9 137.5 22.6 102.1 89.8 137.5 95.1 54.2 40.6 322.2 111.6 283.9 125.7 88.8 46.0 38.5 62.7 119.5 39.1 94.6 145.6 203.4 32.2 50.0 109.3 279.4 MAP3K4 "KIAA0213, MAPKKK4, MEKK4, MTK1" ENSG00000085511 "Mitogen-activated protein kinase kinase kinase 4" Q9Y6R4 6 160991727-161117385 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 87.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 31.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007625 Uncertain Approved Cytosol NA NA "Cluster 34: Basophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 1: K-562 - Erythropoiesis" "Cluster 44: Endometrium - Transcription" Cytosol "HPA007625: AB_1853770" "unprognostic (3.05e-3)" "unprognostic (2.19e-2)" "unprognostic (1.36e-1)" "unprognostic (1.44e-1)" "unprognostic (2.06e-1)" "unprognostic (7.65e-2)" "unprognostic (1.35e-3)" "unprognostic (6.38e-2)" "unprognostic (2.09e-1)" "unprognostic (3.81e-3)" "unprognostic (2.09e-2)" "unprognostic (2.61e-1)" "unprognostic (1.16e-2)" "unprognostic (5.86e-2)" "unprognostic (3.45e-1)" "unprognostic (1.93e-1)" "unprognostic (6.84e-2)" 4.9 3.9 5.1 6.4 4.4 5.8 6.0 9.4 7.7 7.8 0.0 6.0 5.3 9.3 3.6 8.5 7.2 4.5 5.5 6.4 4.8 5.0 4.5 6.2 7.3 2.7 2.0 8.6 6.4 8.0 3.9 7.1 3.6 7.3 5.3 4.1 7.3 6.3 11.1 8.5 5.5 7.6 2.7 6.3 5.8 7.5 3.1 9.6 5.5 10.2 9.8 7.1 6.7 5.6 8.1 9.0 16.8 14.7 9.9 11.9 11.1 9.0 7.9 10.2 10.7 12.6 5.8 16.7 6.4 23.2 14.6 19.7 17.4 18.0 12.4 12.4 14.3 21.8 8.5 12.9 7.9 22.9 10.1 7.6 20.5 10.7 9.6 15.8 13.5 12.4 56.1 18.8 11.0 8.3 15.6 11.9 10.3 5.8 13.8 16.9 15.6 13.3 9.0 5.8 9.7 8.5 17.0 17.8 1.5 14.7 7.4 27.6 13.0 12.4 15.9 11.7 43.3 10.8 9.3 15.3 14.6 23.2 13.2 31.5 4.0 2.7 5.2 3.2 9.3 6.7 7.5 4.8 4.9 9.1 5.2 5.2 0.2 4.1 1.9 6.1 5.7 3.0 5.1 4.4 9.4 7.7 6.4 4.8 2.7 2.0 3.6 2.7 3.1 5.6 19.9 19.2 12.2 32.7 20.8 9.8 10.5 9.7 30.7 18.5 13.3 16.8 20.9 10.0 14.9 14.7 22.9 20.6 17.0 7.1 3.9 9.7 5.5 35.3 55.4 14.5 15.4 12.8 66.1 7.5 11.5 16.1 15.8 39.4 3.8 35.3 6.1 8.3 7.3 23.5 64.5 9.3 6.1 8.2 6.4 4.4 11.5 15.3 0.0 45.9 18.8 14.9 10.3 87.4 57.1 12.5 8.1 12.4 18.2 13.6 9.3 6.9 10.6 29.8 6.6 21.8 19.4 14.7 25.7 28.1 11.8 33.1 25.2 8.1 11.7 16.7 MAP3K6 "ASK2, MAPKKK6, MEKK6" ENSG00000142733 "Mitogen-activated protein kinase kinase kinase 6" O95382 1 27354067-27366961 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 45.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" HPA051192 Approved Approved "Nucleoplasm,Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "Plasma membrane, Actin filaments, Cytosol" "HPA051192: AB_2681380" "unprognostic (1.19e-2)" "unprognostic (2.77e-3)" "unprognostic (2.62e-2)" "unprognostic (1.97e-2)" "prognostic unfavorable (2.13e-4)" "prognostic favorable (7.26e-4)" "prognostic unfavorable (8.76e-4)" "unprognostic (9.10e-2)" "unprognostic (2.79e-1)" "unprognostic (6.91e-2)" "unprognostic (6.56e-2)" "unprognostic (1.25e-1)" "unprognostic (4.65e-3)" "unprognostic (4.95e-2)" "unprognostic (2.79e-1)" "unprognostic (7.07e-3)" "unprognostic (1.50e-1)" 42.9 17.8 17.2 5.5 17.0 0.6 42.6 17.4 20.7 50.2 16.8 25.4 1.8 30.9 4.1 70.0 38.8 4.7 61.8 16.6 17.4 37.3 10.4 54.2 4.7 18.4 17.5 15.6 15.2 5.2 18.0 5.1 17.6 41.3 4.5 1.4 30.3 7.3 15.2 65.7 17.7 12.1 17.3 22.3 23.6 8.3 18.4 2.8 30.3 11.3 7.9 39.8 53.4 16.6 7.2 7.2 6.9 4.4 9.9 12.5 1.4 9.0 5.3 7.2 4.4 2.0 9.4 0.1 8.4 16.4 3.2 10.1 2.0 6.4 3.6 6.5 7.1 0.3 16.0 4.7 2.7 0.5 0.4 10.2 17.6 7.8 2.3 8.8 4.0 0.7 2.0 2.7 10.2 25.1 0.2 9.0 2.2 8.7 8.1 2.3 3.2 1.7 12.9 9.1 2.0 3.0 8.5 7.1 6.3 3.1 4.4 5.0 11.6 13.2 7.2 16.6 5.2 3.5 4.1 0.0 12.1 5.8 4.3 0.9 0.6 3.3 2.8 2.0 3.7 1.5 2.5 3.1 1.3 2.0 1.8 1.6 1.2 0.7 4.5 0.0 3.0 1.2 17.2 17.0 17.4 20.7 16.6 17.4 18.4 17.5 17.6 17.3 18.4 16.6 45.8 19.2 17.8 6.2 3.9 12.5 11.9 8.8 17.1 1.1 8.1 8.9 12.2 5.7 10.3 3.7 0.0 1.2 4.3 8.4 3.9 2.8 0.4 2.3 6.0 27.7 0.0 0.8 1.5 4.4 2.5 10.3 8.6 5.2 2.5 1.2 28.9 0.9 2.8 5.0 1.7 6.1 4.1 8.5 7.1 1.2 16.1 6.4 5.4 5.6 9.3 5.4 8.2 0.0 0.2 12.8 1.9 15.1 3.1 9.5 1.1 1.7 6.2 0.8 6.6 10.8 11.1 13.5 7.7 14.7 14.8 0.1 8.2 0.3 8.8 14.9 MAPK15 "ERK7, ERK8" ENSG00000181085 "Mitogen-activated protein kinase 15" Q8TD08 8 143716340-143722458 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 54.9;fallopian tube: 46.7" "Group enriched" "Detected in some" 5 "Endometrial ciliated cells: 62.5;Respiratory ciliated cells: 107.9" "Cancer enhanced" "Detected in many" "ovarian cancer: 18.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 9.6;HeLa: 20.7;MCF7: 14.3;T-47d: 14.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA002704 Approved "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 20: HeLa - Mitochondria" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Cytosol" "Cell Junctions" "HPA002704: AB_1079307" "unprognostic (9.11e-2)" "unprognostic (1.38e-1)" "unprognostic (8.04e-3)" "unprognostic (2.94e-1)" "unprognostic (2.54e-2)" "unprognostic (1.14e-2)" "unprognostic (1.22e-1)" "unprognostic (6.09e-2)" "unprognostic (2.59e-2)" "unprognostic (1.48e-1)" "unprognostic (3.88e-1)" "unprognostic (9.51e-2)" "unprognostic (2.64e-2)" "unprognostic (1.54e-2)" "unprognostic (5.78e-1)" "unprognostic (6.35e-2)" "unprognostic (1.62e-2)" 1.6 0.1 3.3 0.2 4.0 0.0 1.9 1.7 8.1 6.9 54.9 1.0 0.3 2.5 2.4 1.1 46.7 0.2 0.6 5.0 3.6 10.5 0.3 12.1 0.4 10.2 14.5 0.9 4.4 9.4 6.9 0.3 7.0 2.2 0.2 0.0 2.2 1.7 0.1 4.0 0.8 0.4 6.6 0.7 0.8 11.4 6.4 1.1 16.1 0.0 0.2 0.5 2.1 3.0 0.4 0.6 1.9 0.0 0.0 0.0 0.7 1.8 0.0 0.0 0.0 0.5 9.6 0.0 1.6 0.0 0.0 5.5 0.1 0.2 0.0 1.0 2.0 0.0 20.7 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 1.2 0.0 0.2 3.4 0.0 0.0 14.3 0.0 0.0 2.5 1.2 1.2 0.0 3.7 0.5 1.0 1.6 3.6 5.1 0.0 3.3 0.0 0.2 14.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 4.0 1.7 8.1 5.0 3.6 10.2 14.5 7.0 6.6 6.4 3.0 0.1 0.0 6.4 0.0 0.1 0.4 0.3 5.7 0.0 0.0 1.0 1.3 0.7 0.0 11.8 0.0 0.0 0.0 0.0 0.1 0.0 1.1 13.8 62.5 0.5 0.3 0.0 0.0 0.2 0.0 0.7 0.8 0.0 1.7 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.6 16.2 0.0 0.0 11.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.3 0.0 1.4 107.9 0.0 0.0 0.4 2.2 2.3 0.9 0.0 0.3 0.1 0.2 0.1 0.3 0.1 MAPK8IP2 "IB2, JIP2, PRKM8IPL" ENSG00000008735 "Mitogen-activated protein kinase 8 interacting protein 2" Q13387 22 50600793-50613981 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 84.0;pituitary gland: 35.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 57.8;Enteroendocrine cells: 32.3;Horizontal cells: 99.3;Rod photoreceptor cells: 26.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 19.3;HEK 293: 11.0;SCLC-21H: 15.7;SH-SY5Y: 19.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034780 Uncertain NA NA "Cluster 65: Brain - Ion transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 62: Horizontal cells - Visual perception" "HPA034780: AB_10670283" "unprognostic (7.82e-2)" "unprognostic (7.62e-2)" "unprognostic (3.48e-2)" "unprognostic (1.31e-2)" "unprognostic (5.80e-2)" "unprognostic (6.72e-2)" "unprognostic (1.18e-1)" "unprognostic (2.90e-1)" "unprognostic (5.23e-2)" "unprognostic (9.19e-2)" "unprognostic (8.57e-3)" "unprognostic (8.78e-3)" "unprognostic (6.33e-3)" "unprognostic (6.77e-2)" "unprognostic (1.72e-1)" "unprognostic (5.29e-2)" "unprognostic (4.75e-2)" 1.4 9.2 54.7 0.3 50.2 0.0 1.4 27.5 67.8 1.4 0.0 2.1 0.2 2.1 0.3 1.2 1.5 0.0 0.4 53.7 35.1 0.7 0.5 0.5 0.0 78.0 27.0 7.0 1.8 2.0 35.2 0.3 84.0 1.9 0.1 9.6 2.8 0.2 0.3 1.5 1.0 0.2 18.6 0.8 1.5 7.1 39.4 0.2 1.0 0.1 0.0 0.3 1.0 49.2 0.3 1.1 4.7 4.1 0.4 0.0 3.7 0.0 0.0 1.0 0.6 2.4 0.8 0.6 1.0 0.0 19.3 0.0 6.6 0.0 0.0 0.3 11.0 0.0 0.4 1.2 0.5 0.0 0.8 0.3 5.5 0.0 0.1 0.0 0.0 0.1 1.1 1.8 0.0 0.0 0.0 0.0 3.4 0.8 1.8 1.1 0.7 0.0 0.0 0.1 15.7 19.8 3.7 4.6 0.2 0.9 0.9 0.0 0.0 0.1 0.1 0.6 0.0 1.1 3.1 0.5 0.5 0.5 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.7 50.2 27.5 67.8 53.7 35.1 78.0 27.0 84.0 18.6 39.4 49.2 0.6 3.2 2.0 6.5 0.1 0.4 1.6 0.5 0.6 57.8 2.3 3.9 2.3 2.8 2.7 0.0 16.7 0.2 0.0 0.5 0.0 3.0 0.6 0.7 1.7 0.7 32.3 0.0 15.6 2.5 1.1 0.7 0.0 1.5 0.0 0.5 0.0 0.3 0.1 99.3 13.1 0.5 4.1 0.0 0.4 1.8 5.9 0.3 7.2 3.7 0.2 11.2 0.0 6.0 3.2 0.7 0.1 0.7 0.1 1.2 0.3 0.7 0.3 26.7 0.0 1.3 1.0 3.4 2.7 0.6 0.6 1.1 0.3 0.5 0.6 0.5 MAPKAPK2 MK2 ENSG00000162889 "MAPK activated protein kinase 2" P49137 1 206684905-206734281 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted membrane proteins" "DNA damage" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 185.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "plasmacytoid DC: 21.9" "Lineage enriched" "Detected in all" 6 "dendritic cells: 21.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010297, HPA045556, HPA063708, HPA064435" Approved Supported Nucleoplasm,Centrosome NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 29: U-266 - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm Centrosome "CAB010297: AB_2250405, HPA045556: AB_2679367, HPA063708: AB_2685100, HPA064435: AB_2685263" "unprognostic (7.93e-2)" "unprognostic (1.83e-1)" "unprognostic (5.27e-2)" "unprognostic (5.12e-2)" "unprognostic (1.80e-1)" "unprognostic (1.32e-2)" "prognostic unfavorable (1.93e-4)" "unprognostic (9.85e-2)" "unprognostic (1.68e-1)" "unprognostic (2.00e-1)" "unprognostic (1.01e-2)" "unprognostic (1.35e-1)" "prognostic unfavorable (4.58e-6)" "unprognostic (2.12e-1)" "unprognostic (1.37e-1)" "unprognostic (6.96e-2)" "unprognostic (3.29e-2)" 61.9 80.4 34.8 56.2 39.1 174.6 50.5 36.9 33.9 47.3 38.7 50.3 65.5 53.3 24.1 55.8 50.8 52.5 190.1 30.8 36.6 79.5 66.8 79.3 57.8 53.1 42.1 44.8 53.8 38.0 63.3 25.7 43.9 42.8 35.3 17.6 54.9 33.1 196.7 54.4 61.7 45.4 40.1 78.3 68.2 46.9 45.2 45.6 47.7 94.3 54.4 63.5 46.6 38.6 85.4 33.1 44.8 50.6 128.4 75.0 55.1 57.3 130.0 86.0 80.7 63.8 40.4 40.6 38.8 116.9 54.1 63.0 33.8 61.7 61.4 46.5 25.4 69.1 41.7 41.3 99.0 102.3 219.5 104.1 77.3 82.8 91.3 71.8 71.7 54.1 79.7 180.2 70.5 105.2 41.2 73.3 51.5 29.9 45.1 103.7 94.0 13.5 64.9 51.5 35.7 45.7 68.0 114.2 83.1 83.0 55.4 97.2 68.7 77.6 64.7 91.0 79.7 232.0 220.6 33.2 87.8 60.9 26.0 1.6 0.8 1.8 1.8 1.4 1.6 1.1 1.3 1.7 0.7 1.2 0.6 1.2 3.7 2.6 1.3 21.9 1.8 0.7 34.8 39.1 36.9 33.9 30.8 36.6 53.1 42.1 43.9 40.1 45.2 38.6 49.2 54.5 49.9 15.7 27.9 85.4 52.3 18.3 20.5 12.4 61.4 37.8 102.5 37.1 26.8 31.3 20.9 6.4 185.9 51.9 15.6 30.6 76.2 32.2 40.9 43.7 61.7 15.4 4.7 58.5 9.2 33.4 32.1 46.6 34.9 24.8 19.2 40.0 24.8 0.0 10.6 38.1 16.2 34.6 82.7 36.1 22.7 60.9 33.8 13.1 23.7 21.7 74.2 8.5 17.4 61.6 34.4 17.3 69.6 67.3 22.2 25.0 14.4 16.0 26.3 36.9 48.5 13.7 10.3 31.5 72.0 16.6 46.0 19.2 30.5 75.0 MARCHF3 "MARCH-III, MARCH3, MGC48332, RNF173" ENSG00000173926 "Membrane associated ring-CH-type finger 3" Q86UD3 5 126867714-127030558 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Endocytosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Cytotrophoblasts: 43.8;Syncytiotrophoblasts: 98.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 10.5;naive B-cell: 12.1" "Lineage enriched" "Detected in many" 4 "B-cells: 12.1" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 40.4;HUVEC TERT2: 27.4;TIME: 33.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043406 Uncertain Supported Vesicles NA NA "Cluster 37: B-cells - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Vesicles "HPA043406: AB_10793947" "unprognostic (5.96e-3)" "unprognostic (1.46e-2)" "unprognostic (1.91e-2)" "unprognostic (4.21e-2)" "unprognostic (9.00e-3)" "unprognostic (1.17e-2)" "unprognostic (7.75e-3)" "unprognostic (9.41e-2)" "unprognostic (8.93e-2)" "unprognostic (2.05e-3)" "unprognostic (3.15e-2)" "unprognostic (1.82e-1)" "unprognostic (5.60e-6)" "unprognostic (7.74e-2)" "unprognostic (7.64e-2)" "unprognostic (1.05e-1)" "unprognostic (3.64e-1)" 5.6 2.8 6.1 2.9 5.6 3.7 2.6 5.3 4.1 0.9 1.9 5.3 0.9 1.4 0.0 1.4 1.5 5.2 7.8 3.9 5.7 0.8 0.7 2.4 2.5 11.5 7.1 1.1 2.4 0.3 2.4 1.7 7.9 0.6 5.6 7.4 4.6 0.2 6.5 5.8 2.4 2.9 8.3 1.6 2.4 5.6 7.8 1.3 1.4 3.3 2.1 7.6 0.7 8.5 0.4 1.8 3.9 2.1 3.4 3.2 1.2 14.2 5.9 11.1 16.3 1.9 0.8 3.8 1.3 1.9 2.4 1.1 4.9 2.5 15.3 0.8 4.7 12.2 3.2 1.9 5.6 5.0 3.0 2.4 0.7 40.4 4.8 2.6 27.4 0.6 5.1 0.7 9.3 1.3 0.5 2.3 3.3 3.0 4.6 1.5 15.5 1.2 0.9 2.0 1.3 0.9 3.3 0.5 1.6 1.9 2.9 5.0 33.5 2.2 1.8 12.6 1.6 1.9 2.3 2.3 8.3 3.8 2.0 0.0 0.2 2.8 0.5 0.4 0.1 10.5 0.6 0.3 0.1 12.1 2.3 0.5 0.8 2.3 0.3 0.7 2.9 0.8 6.1 5.6 5.3 4.1 3.9 5.7 11.5 7.1 7.9 8.3 7.8 8.5 3.8 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.4 0.0 0.0 0.0 0.0 43.8 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 3.2 5.8 0.0 0.0 0.0 0.0 0.0 0.0 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 98.6 0.6 0.0 0.0 0.0 MAST1 "KIAA0973, SAST" ENSG00000105613 "Microtubule associated serine/threonine kinase 1" Q9Y2H9 19 12833951-12874952 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 37.7;pituitary gland: 23.3;retina: 15.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 24.7;Cone photoreceptor cells: 43.8;Excitatory neurons: 64.7;Inhibitory neurons: 70.3;Oligodendrocyte precursor cells: 22.1;Rod photoreceptor cells: 20.4" "Cancer enhanced" "Detected in many" "glioma: 3.5" "Region enhanced" "Detected in many" "cerebral cortex: 37.7" "Immune cell enhanced" "Detected in single" "MAIT T-cell: 1.0" "Lineage enriched" "Detected in single" 9 "T-cells: 1.0" "Cell line enhanced" "Detected in many" "AN3-CA: 23.3;SCLC-21H: 40.5;SH-SY5Y: 20.2;U-266/70: 16.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028181, HPA073106" Enhanced Supported Vesicles,Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles Cytosol "HPA028181: AB_10603872, HPA073106: AB_2732218" "unprognostic (6.32e-2)" "unprognostic (3.66e-2)" "unprognostic (3.93e-2)" "unprognostic (2.83e-5)" "unprognostic (1.72e-1)" "unprognostic (4.19e-2)" "unprognostic (2.38e-1)" "unprognostic (8.72e-2)" "unprognostic (1.04e-1)" "unprognostic (3.64e-1)" "unprognostic (8.89e-3)" "unprognostic (3.43e-2)" "unprognostic (3.84e-3)" "unprognostic (1.19e-1)" "unprognostic (7.04e-2)" "unprognostic (2.49e-2)" "unprognostic (1.96e-1)" 0.0 2.2 6.5 0.3 12.1 0.3 0.1 7.3 37.7 0.2 0.0 1.2 0.3 0.0 0.0 0.2 0.1 0.2 0.2 8.3 2.4 0.1 0.6 0.1 0.1 11.2 1.1 0.3 0.6 0.5 23.3 0.0 9.5 0.2 0.1 15.4 0.2 0.0 0.0 3.7 0.4 0.0 0.0 0.1 0.6 5.0 1.2 0.8 0.1 0.0 0.0 0.2 0.3 3.0 3.6 1.6 1.5 23.3 0.0 0.0 1.9 0.2 0.1 0.3 0.9 0.8 1.5 5.8 2.6 0.0 3.9 0.1 6.8 0.1 0.1 4.1 4.5 0.5 5.8 2.6 0.0 1.3 1.2 0.5 0.1 0.8 0.7 1.3 0.0 15.2 5.2 3.0 0.0 0.8 2.4 0.6 6.9 0.6 7.2 15.9 4.6 8.3 0.3 0.2 40.5 20.2 0.8 1.4 4.3 1.2 3.8 2.1 0.0 2.8 4.2 3.1 0.8 16.7 14.5 3.7 5.1 3.1 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 6.5 12.1 7.3 37.7 8.3 2.4 11.2 1.1 9.5 0.0 1.2 3.0 0.5 0.0 2.4 7.8 0.2 0.9 1.6 0.6 0.6 24.7 0.8 2.5 1.0 0.0 0.3 0.0 43.8 0.6 0.4 0.6 0.0 0.4 14.0 0.2 0.2 1.3 0.0 0.0 64.7 0.5 0.6 1.3 0.0 0.3 1.3 0.5 1.1 0.5 0.2 15.2 70.3 0.1 0.0 1.0 1.2 8.2 0.6 0.7 5.4 6.5 0.1 3.7 0.0 22.1 3.0 0.3 2.5 1.2 0.0 1.0 0.9 0.2 1.0 20.4 0.0 2.0 0.5 8.0 5.2 0.7 1.4 0.3 1.0 0.4 0.7 1.2 MATN2 ENSG00000132561 "Matrilin 2" O00339 8 97868840-98036724 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 201.0;Peritubular cells: 258.8;Theca cells: 297.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "MAIT T-cell: 5.2" "Lineage enriched" "Detected in single" 7 "T-cells: 5.2" "Cell line enhanced" "Detected in many" "BJ: 72.5;BJ hTERT+ SV40 Large T+: 78.6;BJ hTERT+ SV40 Large T+ RasG12V: 106.7;HaCaT: 114.4;HBF TERT88: 100.6;SuSa: 67.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB033879 Approved "Secreted to extracellular matrix" NA NA 1500000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 52: Non-specific - Transcription" "CAB033879: AB_2141502" "unprognostic (1.38e-1)" "unprognostic (1.03e-1)" "unprognostic (9.99e-2)" "unprognostic (2.14e-1)" "unprognostic (4.98e-1)" "unprognostic (5.35e-2)" "unprognostic (7.18e-2)" "unprognostic (5.22e-2)" "unprognostic (2.77e-1)" "unprognostic (2.07e-3)" "unprognostic (1.34e-1)" "unprognostic (1.09e-1)" "unprognostic (2.04e-2)" "unprognostic (1.69e-1)" "unprognostic (6.31e-2)" "prognostic unfavorable (9.65e-4)" "unprognostic (6.65e-2)" 54.4 51.0 24.3 30.2 22.5 1.8 43.6 17.6 23.2 194.4 19.3 67.5 58.5 147.0 101.6 32.8 46.9 40.1 110.2 20.0 23.4 39.3 24.6 15.2 18.0 24.1 30.5 116.4 11.3 28.0 9.9 177.9 26.3 104.9 57.8 45.7 42.6 171.9 4.0 62.8 80.6 98.1 18.3 5.9 23.7 31.2 23.4 4.9 271.4 28.5 15.4 103.0 139.2 30.8 24.1 10.8 23.3 2.5 60.7 3.6 15.0 72.5 17.6 78.6 106.7 13.0 8.4 0.1 7.0 29.2 3.5 114.4 2.3 4.4 100.6 0.0 2.9 0.8 6.1 0.9 14.0 0.0 0.0 13.6 9.5 16.1 0.8 22.1 0.5 1.3 0.1 0.2 4.1 11.2 0.0 0.7 7.1 0.3 3.7 0.0 2.4 11.4 5.7 5.3 16.0 1.5 11.5 0.2 19.8 67.3 10.9 1.4 0.6 5.2 31.5 16.1 11.0 0.9 0.2 0.2 18.8 0.4 5.9 0.0 0.1 0.1 0.2 0.4 5.2 0.0 0.7 0.9 0.8 0.2 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.1 24.3 22.5 17.6 23.2 20.0 23.4 24.1 30.5 26.3 18.3 23.4 30.8 27.8 3.2 1.3 11.1 0.3 37.3 10.1 6.2 80.2 6.3 3.8 45.8 29.1 18.6 3.0 16.5 54.2 1.2 0.2 20.6 0.0 9.9 86.0 4.2 22.6 32.4 23.4 3.2 6.4 0.0 1.1 113.1 5.1 5.0 0.0 43.5 201.0 11.0 1.6 0.0 11.5 25.4 0.0 5.0 7.7 108.6 103.5 0.9 28.4 19.7 2.0 8.1 0.0 86.0 59.8 3.2 18.2 258.8 0.0 6.5 118.7 3.4 1.6 52.9 13.1 97.2 17.1 2.5 2.6 7.3 8.5 2.5 2.0 297.5 27.4 1.8 MBD1 "CXXC3, PCM1" ENSG00000141644 "Methyl-CpG binding domain protein 1" Q9UIS9 18 50266882-50281774 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 97.4;Spermatocytes: 136.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009017, CAB036003, HPA068850" Approved Enhanced Nucleoplasm,Vesicles NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 30: Epithelial cell lines - Translation" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Vesicles" "CAB009017: AB_2095559, CAB036003: , HPA068850: AB_2732121" "unprognostic (2.12e-2)" "unprognostic (5.05e-2)" "unprognostic (6.88e-2)" "unprognostic (5.01e-3)" "unprognostic (9.20e-2)" "unprognostic (6.85e-2)" "prognostic unfavorable (5.08e-6)" "unprognostic (5.91e-2)" "unprognostic (2.61e-2)" "unprognostic (4.65e-2)" "unprognostic (1.96e-3)" "prognostic unfavorable (1.70e-6)" "unprognostic (7.06e-3)" "unprognostic (7.70e-2)" "unprognostic (7.05e-2)" "unprognostic (4.61e-2)" "unprognostic (1.31e-1)" 28.5 39.8 23.9 26.2 25.9 44.2 29.1 24.8 28.2 32.3 19.3 35.7 24.8 32.1 20.5 39.2 31.6 19.6 35.7 26.7 22.2 32.5 35.7 29.9 30.2 23.1 22.0 34.8 34.5 32.4 42.8 24.6 21.1 33.0 17.7 24.0 30.5 23.5 51.0 43.4 33.7 20.4 19.5 41.0 33.6 88.1 23.1 29.6 35.4 28.6 24.2 35.3 32.2 25.6 30.9 28.6 31.5 35.9 33.2 26.9 33.9 36.2 41.4 49.2 37.7 21.6 23.9 48.5 25.8 35.3 28.8 54.4 36.3 63.4 28.4 54.7 23.2 30.6 43.8 23.1 63.9 74.8 62.1 31.5 100.4 56.2 127.2 31.1 40.9 47.4 39.3 73.8 38.3 28.5 63.3 38.9 29.8 16.1 22.7 57.8 23.3 53.2 24.4 13.8 41.5 39.5 27.0 25.5 33.2 25.4 32.4 67.4 44.7 53.0 24.1 17.3 37.2 135.8 62.2 51.6 34.3 56.8 49.0 16.0 11.2 22.7 15.3 9.7 14.6 11.6 13.5 12.9 11.2 11.4 13.8 11.4 14.5 14.3 7.8 10.2 13.8 12.6 23.9 25.9 24.8 28.2 26.7 22.2 23.1 22.0 21.1 19.5 23.1 25.6 17.7 9.6 24.6 19.6 20.1 22.7 13.9 18.2 23.3 15.1 16.5 14.5 28.1 14.3 20.5 16.5 18.8 31.1 25.0 24.5 13.7 15.7 85.1 17.1 16.1 17.6 13.1 9.7 20.4 13.8 24.2 16.5 28.1 17.3 8.8 17.7 13.9 18.1 18.7 15.2 17.3 19.5 24.4 15.8 11.1 97.4 15.5 17.5 16.0 9.4 15.7 17.4 14.4 12.1 16.4 21.1 24.5 19.2 34.6 14.4 21.3 9.7 16.9 20.3 13.1 14.8 18.9 136.0 32.5 21.6 29.3 51.4 20.0 28.1 18.6 17.0 MBNL3 "CHCR, FLJ11316, MBLX39, MBXL" ENSG00000076770 "Muscleblind like splicing regulator 3" Q9NUK0 X 132369317-132489968 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 59.3;placenta: 170.8" "Group enriched" "Detected in many" 4 "Cytotrophoblasts: 328.3;Hepatocytes: 119.6;Syncytiotrophoblasts: 344.1" "Cancer enhanced" "Detected in all" "liver cancer: 13.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CACO-2: 123.8;Hep G2: 171.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA001584 Enhanced Approved "Golgi apparatus,Vesicles" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 28: Placenta - Pregnancy" "Cluster 39: CACO-2 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" Vesicles "Golgi apparatus" "HPA001584: AB_1079326" "unprognostic (3.38e-2)" "unprognostic (1.40e-2)" "unprognostic (1.82e-1)" "prognostic unfavorable (1.57e-4)" "unprognostic (1.87e-1)" "unprognostic (2.67e-3)" "unprognostic (8.74e-2)" "unprognostic (3.46e-2)" "unprognostic (2.19e-2)" "unprognostic (5.77e-3)" "unprognostic (4.36e-3)" "unprognostic (1.65e-1)" "unprognostic (1.07e-1)" "unprognostic (1.67e-1)" "unprognostic (2.43e-1)" "unprognostic (8.28e-2)" "unprognostic (2.37e-1)" 6.8 11.6 1.3 8.7 1.9 14.8 4.7 1.7 1.0 3.7 2.4 11.7 9.9 4.9 24.3 10.9 9.4 5.7 9.7 1.1 4.4 8.0 59.3 5.9 13.8 3.6 3.1 4.8 10.0 4.2 1.6 170.8 3.2 4.0 11.5 0.1 6.6 11.1 0.6 12.6 9.8 4.0 2.0 11.3 13.0 42.8 1.6 14.3 8.2 3.4 15.1 8.5 2.8 3.7 7.2 0.0 8.6 1.4 1.6 3.6 15.7 0.5 3.2 1.1 0.0 123.8 22.7 32.6 0.7 1.3 1.1 7.7 19.8 8.2 0.8 3.3 7.6 29.1 25.9 171.5 1.5 32.9 10.2 1.5 7.1 0.0 3.6 0.1 1.1 20.4 2.6 9.2 1.6 19.2 56.3 12.5 1.3 27.5 1.6 53.2 10.7 18.6 5.7 18.6 3.1 10.5 14.8 8.6 4.3 15.1 3.1 8.4 3.9 6.3 1.2 8.2 6.7 18.2 13.0 47.0 1.2 21.8 20.2 11.9 7.9 5.5 16.6 9.9 14.4 20.6 9.8 11.6 8.8 25.5 10.0 11.2 1.2 18.7 21.7 17.0 2.2 9.1 1.3 1.9 1.7 1.0 1.1 4.4 3.6 3.1 3.2 2.0 1.6 3.7 4.1 3.2 6.8 16.0 16.9 8.8 2.2 2.1 5.2 0.7 3.5 3.6 14.7 41.5 5.0 11.0 0.0 328.3 9.5 12.8 3.9 1.5 5.8 12.6 1.3 3.6 6.7 55.8 0.9 5.4 56.6 7.5 15.3 6.6 8.8 6.8 6.4 119.6 29.3 0.0 0.9 9.8 0.0 27.2 6.5 9.4 23.0 9.6 7.2 30.0 10.6 0.2 9.2 0.0 20.6 1.3 3.6 50.8 12.2 1.4 6.4 9.7 4.5 1.9 0.0 3.1 2.7 2.1 1.7 13.6 8.5 344.1 10.3 5.7 10.3 3.3 MCAM "CD146, HEMCAM, MelCAM, METCAM, MUC18" ENSG00000076706 "Melanoma cell adhesion molecule" P43121 11 119308529-119321521 "CD markers, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 128.5;Endothelial cells: 153.5;Muller glia cells: 89.8;Sertoli cells: 322.1;Smooth muscle cells: 384.6" "Cancer enhanced" "Detected in all" "melanoma: 83.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "HUVEC TERT2: 1121.0;TIME: 1107.4;WM-115: 869.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002147, HPA008848" Enhanced Approved "Plasma membrane" NA NA 1900000000 "Cluster 13: T-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" "CAB002147: AB_563499, HPA008848: AB_1078445" "unprognostic (6.45e-2)" "prognostic unfavorable (7.61e-4)" "unprognostic (7.03e-2)" "unprognostic (1.22e-2)" "unprognostic (6.67e-2)" "unprognostic (2.34e-1)" "unprognostic (2.23e-2)" "unprognostic (8.42e-2)" "unprognostic (2.09e-2)" "unprognostic (1.45e-1)" "unprognostic (1.58e-1)" "unprognostic (9.39e-2)" "prognostic unfavorable (5.14e-4)" "unprognostic (8.75e-3)" "unprognostic (7.84e-2)" "unprognostic (2.31e-1)" "unprognostic (2.79e-3)" 332.7 30.0 36.6 68.4 46.1 1.2 180.6 45.7 45.3 96.6 25.3 166.3 29.2 175.8 47.0 89.2 136.4 66.8 118.0 35.3 44.7 42.0 10.5 116.4 19.6 59.4 43.1 60.9 22.0 93.9 17.8 168.0 52.2 78.1 32.2 12.2 39.5 148.0 40.7 50.9 73.0 160.9 36.2 35.4 97.7 9.7 50.2 15.5 58.7 37.4 15.4 174.5 79.8 44.8 0.7 5.1 4.7 0.3 21.5 0.3 23.2 3.2 0.3 29.9 13.3 17.9 0.9 1.2 94.5 10.7 44.7 3.2 38.3 8.1 15.0 56.9 14.5 1.2 102.4 19.8 51.0 0.1 0.4 15.2 0.3 40.8 18.7 1.1 1121.0 7.1 38.7 1.5 6.1 0.0 1.2 9.3 19.9 0.2 4.4 0.9 147.8 32.9 27.1 0.0 12.5 3.9 87.1 2.1 249.2 46.2 4.3 0.9 1107.4 3.1 156.7 0.2 89.1 2.4 2.3 0.6 43.1 0.1 869.3 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 36.6 46.1 45.7 45.3 35.3 44.7 59.4 43.1 52.2 36.2 50.2 44.8 128.5 0.0 2.3 1.3 1.4 4.7 0.6 11.1 8.0 1.2 9.9 19.7 65.8 18.6 1.1 0.0 22.9 0.5 2.5 0.1 0.0 17.3 1.7 7.8 14.0 153.5 0.0 0.0 1.4 0.4 38.7 14.1 1.5 10.3 0.0 18.2 60.0 0.6 0.8 0.0 3.5 0.0 0.0 1.3 7.0 0.7 0.9 2.4 21.4 14.0 0.6 89.8 1.0 18.6 45.2 1.6 0.0 25.2 3.1 1.7 0.0 0.9 1.3 4.0 322.1 9.9 384.6 2.1 1.6 1.7 3.3 0.4 9.3 4.9 0.1 1.8 MCF2 "ARHGEF21, DBL" ENSG00000101977 "MCF.2 cell line derived transforming sequence" P10911 X 139581770-139708227 "Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 29.5;seminal vesicle: 17.0;testis: 18.6" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 98.0;Excitatory neurons: 27.8;Inhibitory neurons: 36.2;Oligodendrocyte precursor cells: 20.6;Theca cells: 22.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 12 "U-251 MG: 37.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (2.42e-1)" "unprognostic (2.18e-2)" "unprognostic (1.46e-2)" "unprognostic (5.11e-4)" "unprognostic (8.95e-2)" "unprognostic (3.99e-2)" "unprognostic (1.24e-1)" "unprognostic (2.28e-1)" "unprognostic (1.80e-1)" "unprognostic (1.28e-1)" "unprognostic (2.63e-2)" "unprognostic (7.77e-2)" "unprognostic (2.33e-3)" "unprognostic (3.68e-2)" "unprognostic (2.92e-2)" "unprognostic (4.62e-4)" "unprognostic (4.02e-2)" 0.2 29.5 5.8 0.4 4.5 0.7 0.1 6.4 8.8 0.0 1.7 0.1 0.0 0.1 12.3 0.0 0.8 0.7 1.0 4.4 7.0 1.5 0.2 0.1 0.6 9.1 7.4 10.2 0.2 0.0 3.4 0.0 9.7 1.2 0.0 9.2 1.0 17.0 0.1 0.1 0.3 0.0 5.5 1.1 0.2 18.6 14.1 0.5 1.1 0.2 0.1 0.2 0.1 5.9 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.1 0.3 0.0 0.0 0.0 1.6 0.0 0.2 0.0 0.2 0.0 0.0 0.2 0.0 0.5 3.1 0.0 0.5 0.6 2.5 0.0 0.0 0.1 1.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.3 0.6 37.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.8 4.5 6.4 8.8 4.4 7.0 9.1 7.4 9.7 5.5 14.1 5.9 0.2 0.0 0.0 3.6 0.3 0.1 0.3 0.2 0.6 2.2 0.6 0.4 1.8 0.0 0.0 0.0 98.0 0.0 0.3 0.1 0.0 0.0 1.0 0.1 0.1 0.1 0.0 0.0 27.8 0.0 0.0 0.7 0.0 0.1 0.0 2.2 0.4 0.2 0.1 0.0 36.2 0.0 0.0 0.6 0.3 2.5 1.2 0.2 0.0 4.7 1.4 1.0 4.1 20.6 7.6 0.1 0.0 8.2 0.1 0.4 0.0 0.6 0.0 2.4 0.0 0.1 0.4 0.6 0.8 0.1 0.0 0.0 0.3 22.8 0.0 0.2 MCOLN2 "FLJ36691, TRP-ML2, TRPML2" ENSG00000153898 "Mucolipin 2" Q8IZK6 1 84925583-84997113 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Adaptive immunity, Calcium transport, Immunity, Innate immunity, Ion transport, Protein transport, Transport" "Calcium channel, Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 15.1;lymphoid tissue: 13.1" "Cell type enhanced" "Detected in many" "B-cells: 26.3;dendritic cells: 43.6;Distal enterocytes: 31.4;Early spermatids: 53.1;Langerhans cells: 100.8;monocytes: 32.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 29.7" "Group enriched" "Detected in many" 14 "B-cells: 10.3;dendritic cells: 29.7;T-cells: 8.9" "Cell line enhanced" "Detected in many" "Daudi: 21.9;HAP1: 14.7;HDLM-2: 26.9;HEK 293: 13.6;THP-1: 28.5;U-698: 18.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA019114 Uncertain NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 41: Macrophages - Immune response" "HPA019114: AB_1853645" "unprognostic (3.02e-2)" "unprognostic (5.67e-2)" "unprognostic (3.07e-1)" "unprognostic (1.44e-1)" "unprognostic (2.47e-1)" "unprognostic (5.66e-3)" "unprognostic (2.38e-1)" "prognostic favorable (2.56e-4)" "unprognostic (8.92e-2)" "unprognostic (1.48e-2)" "unprognostic (6.84e-2)" "unprognostic (2.21e-2)" "unprognostic (3.12e-4)" "unprognostic (3.68e-2)" "unprognostic (4.69e-2)" "unprognostic (1.24e-1)" "unprognostic (4.23e-2)" 0.7 8.8 0.2 5.3 0.2 2.9 1.0 1.0 0.4 1.1 0.7 10.2 1.7 1.0 4.0 0.7 2.6 1.6 0.4 0.3 0.1 1.1 0.7 5.4 12.9 0.4 0.1 0.5 0.8 1.1 0.6 2.6 0.3 0.7 15.1 0.1 0.8 0.2 0.2 2.1 5.5 0.6 0.1 6.7 2.1 1.5 0.3 2.3 0.5 0.2 13.1 1.6 0.7 0.5 1.5 1.6 0.0 4.0 0.8 0.2 0.3 1.0 5.5 1.6 2.0 0.0 0.1 21.9 0.5 0.0 2.6 0.1 14.7 1.8 1.5 26.9 13.6 1.9 0.4 0.0 1.3 0.0 1.8 0.3 0.0 1.3 1.0 0.1 0.0 5.1 0.0 0.0 0.3 0.5 0.3 0.0 1.6 0.0 2.9 0.0 3.3 0.0 0.1 0.2 0.9 0.0 0.1 0.2 9.2 0.2 2.4 28.5 0.1 1.3 2.1 0.0 4.2 0.0 0.0 18.5 1.2 0.0 4.0 0.1 0.3 0.0 5.9 1.1 2.1 10.3 5.0 8.9 7.1 3.7 0.6 4.5 0.2 0.4 0.2 29.7 0.2 2.6 0.2 0.2 1.0 0.4 0.3 0.1 0.4 0.1 0.3 0.1 0.3 0.5 0.4 0.0 0.6 0.0 26.3 4.5 0.4 0.1 1.2 0.0 1.1 1.8 0.5 0.0 1.3 1.8 0.0 0.1 43.6 31.4 0.0 0.1 53.1 12.3 6.0 0.4 2.4 1.3 0.9 1.4 0.1 1.5 1.5 24.5 0.0 0.1 0.7 0.0 0.7 0.0 0.5 4.5 0.0 1.3 100.8 19.6 0.0 14.4 8.8 2.8 32.3 0.0 1.0 0.0 1.4 0.4 4.7 0.0 13.8 0.6 0.0 2.3 1.5 0.0 0.0 0.7 0.3 1.6 4.3 0.0 3.3 0.3 21.8 1.6 5.4 0.1 MDH1B "FLJ25341, RP11-95H11" ENSG00000138400 "Malate dehydrogenase 1B" Q5I0G3 2 206737763-206765328 "Metabolic proteins, Predicted intracellular proteins" "Tricarboxylic acid cycle" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 15.7;fallopian tube: 22.5;testis: 24.5" "Cell type enhanced" "Detected in many" "Early spermatids: 186.0;Endometrial ciliated cells: 50.1;Late spermatids: 33.7;Respiratory ciliated cells: 100.5;Spermatocytes: 114.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "RPTEC TERT1: 3.6;SCLC-21H: 3.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA073761 Approved NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 49: Ciliated cells - Cilium organization" "HPA073761: AB_2732241" "unprognostic (1.03e-2)" "unprognostic (9.44e-2)" "unprognostic (1.58e-1)" "unprognostic (9.84e-2)" "unprognostic (1.54e-1)" "unprognostic (6.31e-2)" "unprognostic (2.55e-2)" "unprognostic (8.21e-2)" "unprognostic (2.01e-1)" "unprognostic (3.66e-2)" "unprognostic (3.23e-3)" "unprognostic (3.08e-1)" "unprognostic (6.10e-3)" "unprognostic (1.15e-1)" "unprognostic (3.09e-2)" "unprognostic (7.84e-3)" "unprognostic (3.01e-1)" 0.4 1.5 2.2 0.2 2.5 0.1 1.2 1.9 2.4 1.7 15.7 1.2 0.0 1.7 1.7 0.5 22.5 0.8 1.3 2.4 2.8 3.1 0.3 2.0 0.3 4.2 5.3 1.0 0.9 4.2 9.3 0.0 3.9 0.9 0.5 8.5 1.0 1.3 0.4 0.4 0.3 0.8 3.5 0.2 0.7 24.5 2.8 0.5 4.8 0.5 0.2 0.5 0.4 3.0 0.3 1.2 0.9 2.5 0.1 1.1 0.3 0.0 0.4 0.5 0.3 0.1 0.8 0.5 0.5 0.1 1.1 0.6 0.0 0.7 0.5 0.0 0.0 0.2 0.2 0.8 0.5 0.4 1.2 0.7 0.2 0.0 0.1 0.5 0.7 1.1 0.0 0.7 0.3 1.5 0.8 0.3 1.6 0.1 1.4 1.6 0.9 0.0 3.6 0.2 3.5 0.7 1.1 0.5 0.3 0.5 1.1 0.0 0.0 0.6 0.6 0.1 0.3 0.3 1.6 0.2 1.3 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 2.5 1.9 2.4 2.4 2.8 4.2 5.3 3.9 3.5 2.8 3.0 0.2 6.4 1.5 6.8 0.0 0.8 1.4 3.9 1.8 3.0 2.1 2.4 1.3 2.8 6.4 0.0 0.0 0.1 0.0 0.0 13.7 1.3 186.0 50.1 1.2 0.6 1.2 0.0 8.9 0.0 0.1 1.3 1.5 1.6 0.0 1.1 0.0 0.0 0.1 3.3 6.3 0.0 10.2 0.0 0.2 33.7 1.8 0.5 1.8 1.9 0.0 9.6 0.0 1.0 1.3 0.1 0.0 3.0 0.0 0.4 0.0 6.0 100.5 10.2 0.0 0.5 1.7 114.9 5.1 0.5 0.3 0.0 0.2 1.6 0.1 0.9 MECOM "EVI1, KMT8E, MDS1, MDS1-EVI1, PRDM3" ENSG00000085276 "MDS1 and EVI1 complex locus" Q03112 3 169083499-169663775 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Apoptosis, Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Methyltransferase, Transferase" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 73.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 184.8;Collecting duct cells: 125.0;Gastric mucus-secreting cells: 111.1;Glandular and luminal cells: 107.7;Microglial cells: 346.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 55.5;RPTEC TERT1: 71.2;RT4: 119.6;TIME: 53.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046537 Supported Supported "Nuclear speckles" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 46: Fibroblasts - ECM organization" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" "Nuclear speckles" "HPA046537: AB_2679689" "unprognostic (4.09e-2)" "unprognostic (1.96e-1)" "unprognostic (3.24e-3)" "unprognostic (7.29e-2)" "unprognostic (2.87e-2)" "unprognostic (2.53e-1)" "unprognostic (1.83e-2)" "unprognostic (4.77e-3)" "unprognostic (1.53e-2)" "unprognostic (3.27e-3)" "prognostic unfavorable (2.59e-4)" "unprognostic (1.87e-1)" "unprognostic (2.60e-3)" "unprognostic (6.54e-2)" "unprognostic (1.03e-1)" "unprognostic (2.81e-2)" "unprognostic (3.37e-3)" 16.0 0.9 7.3 7.3 7.2 1.4 12.3 8.5 7.3 21.3 2.4 24.9 19.8 17.3 4.4 13.5 23.4 8.3 13.0 4.9 6.3 41.3 1.4 25.5 1.5 9.1 7.2 2.3 23.3 1.7 4.2 17.4 8.9 6.9 30.0 1.8 8.8 8.0 4.3 2.6 10.2 8.0 4.1 6.2 73.3 3.0 8.1 2.0 5.7 12.0 5.3 30.4 7.5 6.3 25.8 0.7 0.9 0.2 3.7 2.7 1.1 3.7 4.2 1.1 2.2 10.7 26.1 0.9 39.1 0.6 5.5 13.4 10.2 15.7 3.1 1.4 16.6 16.7 7.6 1.1 0.4 0.3 5.1 5.7 2.2 1.0 12.1 12.0 55.5 1.4 13.0 1.8 10.3 9.8 0.9 0.4 1.7 13.5 6.6 9.8 13.1 0.3 71.2 119.6 1.0 3.1 1.3 6.7 0.3 1.5 7.1 1.1 53.4 9.7 6.6 2.5 16.9 1.4 0.7 0.9 4.8 1.0 1.6 0.9 0.4 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.5 0.2 0.0 0.0 0.3 0.4 0.5 1.6 0.1 0.0 7.3 7.2 8.5 7.3 4.9 6.3 9.1 7.2 8.9 4.1 8.1 6.3 80.2 60.9 184.8 16.0 0.6 2.2 33.3 29.4 10.2 0.0 1.2 0.9 11.4 2.8 69.6 125.0 0.0 1.1 0.1 25.5 52.8 1.6 10.4 71.9 5.8 70.5 19.9 7.4 10.3 75.4 0.2 4.8 111.1 107.7 9.5 0.8 69.3 0.2 0.0 0.0 9.1 29.0 20.3 0.6 1.9 3.2 0.3 2.6 1.8 346.6 1.0 0.0 0.0 6.0 13.8 49.8 19.3 0.0 0.3 13.9 6.2 0.7 53.2 0.1 0.0 1.4 5.7 3.0 1.2 39.4 1.4 0.4 1.3 0.5 53.9 45.4 MED21 "SRB7, SURB7" ENSG00000152944 "Mediator complex subunit 21" Q13503 12 27022546-27066343 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 228.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017177 Uncertain Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 23: Testis - Cell cycle regulation" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "Nucleoli, Cytosol" "HPA017177: AB_1857665" "unprognostic (3.02e-1)" "unprognostic (7.33e-2)" "unprognostic (2.66e-1)" "unprognostic (1.12e-1)" "unprognostic (1.39e-1)" "unprognostic (2.10e-1)" "unprognostic (7.18e-3)" "unprognostic (1.01e-1)" "unprognostic (4.78e-3)" "unprognostic (7.32e-2)" "unprognostic (1.03e-2)" "unprognostic (1.54e-1)" "prognostic favorable (3.74e-8)" "unprognostic (3.18e-2)" "unprognostic (1.96e-1)" "unprognostic (1.71e-2)" "unprognostic (1.42e-2)" 16.7 24.9 10.5 9.9 11.4 29.0 18.2 14.6 15.2 25.2 11.2 20.4 12.2 20.3 15.0 23.9 19.2 15.0 25.4 11.2 11.6 26.2 16.1 16.6 13.0 9.4 9.5 24.9 13.3 25.7 17.8 16.4 9.6 18.3 16.9 12.4 20.9 17.0 27.9 15.8 12.0 21.8 10.1 12.0 16.3 29.7 10.5 21.1 18.9 35.5 17.1 22.6 23.8 11.3 36.6 40.5 18.6 27.5 41.3 36.1 29.7 46.2 24.5 30.2 32.5 42.5 37.3 21.4 25.9 26.5 54.2 30.7 41.1 36.3 53.8 21.6 36.8 36.5 37.9 22.4 22.0 41.3 21.2 31.1 46.4 45.3 50.0 54.0 46.6 30.8 25.8 28.2 34.7 27.1 38.1 63.8 54.3 50.1 49.8 29.3 133.5 23.7 28.1 37.4 13.4 17.7 57.3 18.2 26.1 79.9 34.6 26.4 39.0 34.8 28.7 43.3 40.3 9.6 21.4 37.8 34.7 39.4 23.3 54.9 23.8 33.6 26.2 26.0 25.4 28.8 30.0 30.8 22.5 26.9 35.2 30.4 18.7 19.0 24.6 18.3 34.5 26.9 10.5 11.4 14.6 15.2 11.2 11.6 9.4 9.5 9.6 10.1 10.5 11.3 30.9 16.0 23.0 7.8 35.4 98.9 121.4 95.1 72.8 9.9 39.4 33.5 32.1 22.8 45.0 53.3 0.0 62.0 33.1 18.5 93.9 41.7 228.6 32.7 26.3 33.0 17.9 68.8 23.8 38.0 56.8 50.8 18.8 35.1 18.4 31.3 25.7 21.8 31.7 13.5 17.6 20.8 65.1 21.7 50.2 87.8 48.4 22.4 71.2 7.5 29.1 27.1 11.3 10.6 14.4 33.4 19.9 47.4 24.5 85.3 22.4 109.3 20.8 13.6 19.7 37.4 54.8 157.7 61.8 70.5 101.3 61.0 46.7 30.6 20.4 145.8 MEDAG "AWMS3, C13orf33, FLJ14834, MEDA-4" ENSG00000102802 "Mesenteric estrogen dependent adipogenesis" Q5VYS4 13 30906271-30925572 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 163.7" "Group enriched" "Detected in many" 4 "Endometrial stromal cells: 80.2;Fibroblasts: 122.4;Skeletal myocytes: 80.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC diff: 312.4;ASC TERT1: 87.4;U-2197: 175.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (2.28e-1)" "unprognostic (1.08e-1)" "unprognostic (6.44e-2)" "unprognostic (3.42e-2)" "unprognostic (6.06e-3)" "unprognostic (8.80e-2)" "unprognostic (1.07e-1)" "unprognostic (3.71e-3)" "unprognostic (1.37e-1)" "unprognostic (1.50e-1)" "unprognostic (2.34e-1)" "unprognostic (1.69e-1)" "prognostic unfavorable (3.29e-5)" "unprognostic (8.69e-3)" "unprognostic (2.48e-1)" "unprognostic (5.41e-3)" "unprognostic (7.52e-2)" 163.7 4.0 0.6 15.8 0.8 0.3 57.0 0.5 1.5 19.1 4.6 14.5 2.5 28.1 26.9 8.4 36.3 15.1 30.1 0.6 1.9 11.6 0.8 16.0 1.5 0.7 0.8 11.8 14.2 0.8 6.1 6.8 0.7 7.5 6.5 0.1 15.5 2.5 14.8 21.4 11.5 23.4 0.7 0.4 15.4 7.0 1.1 1.9 26.8 6.2 0.8 66.4 10.1 0.5 0.0 0.0 0.0 0.0 312.4 87.4 0.0 0.6 0.1 1.3 1.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.6 0.5 0.1 0.0 0.0 0.0 0.0 6.2 0.0 0.1 37.1 0.0 45.9 0.0 0.2 42.7 0.0 0.0 0.0 4.2 0.0 0.0 0.2 4.0 0.0 0.0 0.0 37.9 0.0 0.0 0.0 6.6 0.0 0.0 0.3 0.0 6.0 0.1 0.0 46.9 0.0 0.2 175.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.8 0.5 1.5 0.6 1.9 0.7 0.8 0.7 0.7 1.1 0.5 12.0 0.0 0.5 0.3 0.0 11.5 0.2 0.1 0.0 0.0 0.1 0.3 4.5 5.7 1.3 0.0 0.0 0.1 0.3 0.0 0.0 0.9 1.1 2.0 80.2 13.9 0.0 0.0 0.4 0.0 0.5 122.4 2.0 1.7 0.0 0.0 2.2 0.0 1.0 0.0 0.3 0.0 0.0 0.0 20.6 2.2 19.0 1.4 10.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 9.8 0.1 1.7 0.0 0.2 0.7 0.0 0.0 80.4 19.6 0.0 0.0 0.7 10.4 0.3 1.1 5.3 0.0 0.6 MEGF11 "DKFZp434L121, KIAA1781" ENSG00000157890 "Multiple EGF like domains 11" A6BM72 15 65895079-66253747 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 23.0;fallopian tube: 7.8;kidney: 8.4;retina: 14.2" "Group enriched" "Detected in many" 9 "Early spermatids: 175.8;Horizontal cells: 126.2;Late spermatids: 177.8;Oligodendrocyte precursor cells: 460.4" "Group enriched" "Detected in some" 5 "endometrial cancer: 0.7;glioma: 2.3;renal cancer: 0.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 3.3;HEK 293: 2.7;RPTEC TERT1: 9.2;SCLC-21H: 7.2;U-698: 2.0" "Region enriched" "Detected in all" 4 "cerebellum: 35.0" "Region enriched" "Detected in all" 7 "cerebellum: 25.8" NA NA "Cluster 77: Retina - Visual perception" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 68: Oligodendrocytes - Mixed function" "unprognostic (2.97e-2)" "unprognostic (1.23e-1)" "unprognostic (7.95e-2)" "unprognostic (1.84e-2)" "unprognostic (9.02e-3)" "unprognostic (6.45e-3)" "unprognostic (1.51e-1)" "unprognostic (4.08e-2)" "unprognostic (2.92e-1)" "unprognostic (1.23e-1)" "unprognostic (6.79e-3)" "unprognostic (6.81e-3)" "unprognostic (5.71e-5)" "unprognostic (7.94e-2)" "unprognostic (9.78e-3)" "unprognostic (2.03e-1)" "unprognostic (4.89e-2)" 0.0 0.1 8.3 0.2 5.3 0.3 0.1 23.0 7.0 0.1 0.4 0.1 0.0 0.1 0.8 0.1 7.8 0.0 0.1 10.5 7.5 8.4 0.0 0.5 0.1 6.6 8.8 0.3 0.2 0.0 3.0 0.0 7.0 0.1 0.0 14.2 0.1 0.1 0.1 1.3 0.1 0.0 4.5 0.2 0.3 3.9 8.0 0.1 0.0 0.0 0.0 0.0 0.1 7.4 0.0 0.1 0.3 3.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.5 0.0 0.2 0.0 0.2 0.0 0.1 0.1 2.7 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.8 0.1 0.0 1.2 0.0 0.0 9.2 0.2 7.2 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.1 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 8.3 5.3 23.0 7.0 10.5 7.5 6.6 8.8 7.0 4.5 8.0 7.4 0.2 0.0 3.7 5.2 0.4 2.2 0.7 1.0 0.6 5.3 0.8 0.0 1.4 0.0 0.3 3.7 8.4 0.3 0.4 0.0 0.0 0.1 175.8 0.3 0.3 1.5 0.0 0.4 9.5 0.2 0.1 0.7 2.6 0.8 0.0 0.2 2.9 0.0 0.1 126.2 18.4 0.0 0.0 0.3 3.5 177.8 2.5 0.4 0.0 1.0 0.0 4.4 0.0 460.4 1.7 0.1 0.1 1.5 1.3 0.6 0.0 2.2 0.8 25.7 0.0 1.0 0.5 2.9 1.9 0.6 3.8 0.5 0.9 0.1 0.0 0.5 MEGF6 EGFL3 ENSG00000162591 "Multiple EGF like domains 6" O75095 1 3487951-3611508 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 22.4;Alveolar cells type 2: 20.6;Basal keratinocytes: 18.4;Basal squamous epithelial cells: 23.3;Melanocytes: 19.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 1.9" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BJ: 51.1;HeLa: 56.3;hTERT-RPE1: 69.7;U-2197: 55.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA052129 Uncertain Approved "Microtubules,Cytokinetic bridge" "Secreted to blood" Yes No 1700000 "Cluster 52: Eosinophils - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 20: HeLa - Mitochondria" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Microtubules "Cytokinetic bridge" "HPA052129: AB_2681739" "unprognostic (1.95e-1)" "unprognostic (1.49e-1)" "prognostic unfavorable (3.08e-4)" "unprognostic (1.16e-2)" "unprognostic (2.38e-1)" "prognostic favorable (6.57e-4)" "unprognostic (1.19e-1)" "unprognostic (4.16e-2)" "unprognostic (1.73e-1)" "unprognostic (1.47e-1)" "unprognostic (2.90e-2)" "unprognostic (2.03e-1)" "unprognostic (3.09e-3)" "unprognostic (1.60e-1)" "unprognostic (1.64e-1)" "unprognostic (9.51e-2)" "unprognostic (3.43e-2)" 25.9 4.3 2.9 3.9 2.7 10.8 20.0 2.6 2.8 14.5 1.4 14.1 2.1 9.6 1.4 13.2 28.9 11.2 14.2 1.9 3.2 5.9 5.0 22.1 5.5 3.5 5.8 18.0 6.5 0.4 4.1 2.8 3.6 26.5 1.1 1.8 19.3 4.7 4.8 44.6 10.0 1.4 2.1 10.7 10.1 3.3 3.7 3.4 11.6 1.9 3.4 11.0 22.8 1.9 11.6 14.1 4.3 6.6 0.4 0.3 1.0 51.1 14.1 5.2 1.6 3.3 10.4 0.0 13.8 24.6 4.4 6.7 0.0 0.5 1.7 0.0 0.4 0.0 56.3 3.3 0.0 0.2 0.9 0.1 0.6 0.4 0.8 69.7 5.6 0.1 0.0 0.0 0.1 6.0 0.0 10.9 2.7 3.3 0.9 2.2 3.0 6.2 1.1 3.8 3.8 3.1 18.8 1.1 6.4 11.4 4.9 1.5 2.2 19.6 1.7 55.6 3.9 0.2 0.0 0.0 0.1 0.0 0.0 1.0 0.0 1.9 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.2 0.3 0.0 0.8 0.0 0.0 0.0 0.8 0.1 2.9 2.7 2.6 2.8 1.9 3.2 3.5 5.8 3.6 2.1 3.7 1.9 5.0 22.4 20.6 8.8 2.7 18.4 7.1 3.9 23.3 0.8 3.6 3.0 3.3 5.7 4.4 1.8 0.0 0.2 0.4 0.6 0.0 3.6 0.2 1.4 0.6 7.0 0.0 4.8 6.5 1.4 1.3 9.4 6.6 5.0 1.3 9.8 16.8 0.9 1.0 0.0 7.2 1.4 0.0 0.3 7.5 0.5 11.5 2.8 19.6 5.6 0.7 14.7 1.0 4.5 5.2 4.5 0.1 3.4 0.4 4.0 0.5 1.2 0.3 1.2 0.0 0.5 2.7 0.3 1.1 7.6 11.4 0.4 3.6 0.1 1.1 2.7 MEMO1 "C2orf4, CGI-27, MEMO" ENSG00000162959 "Mediator of cell motility 1" Q9Y316 2 31865060-32011230 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 115.0;Inhibitory neurons: 111.2;Microglial cells: 100.2;Oligodendrocyte precursor cells: 106.1;Oligodendrocytes: 134.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042603, HPA057952" Approved Approved Vesicles NA NA 9100 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 24: NB-4 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA042603: AB_10806243, HPA057952: AB_2683562" "unprognostic (1.33e-1)" "unprognostic (1.28e-3)" "unprognostic (1.81e-1)" "unprognostic (2.94e-5)" "unprognostic (1.02e-2)" "unprognostic (3.96e-2)" "unprognostic (2.24e-4)" "unprognostic (1.70e-2)" "unprognostic (6.73e-2)" "unprognostic (8.37e-3)" "unprognostic (1.18e-1)" "unprognostic (1.34e-1)" "unprognostic (5.95e-9)" "unprognostic (6.57e-2)" "unprognostic (2.26e-1)" "unprognostic (3.77e-2)" "unprognostic (4.23e-2)" 17.2 23.7 15.0 23.2 13.7 45.7 14.7 14.0 14.1 15.1 9.9 17.5 16.7 14.4 16.7 33.6 13.1 13.4 36.3 13.4 13.7 16.4 35.9 13.9 31.9 14.2 14.2 10.7 17.3 14.6 11.9 20.6 13.9 14.2 20.7 11.7 16.8 13.6 58.8 19.2 16.7 19.5 13.4 20.3 17.3 62.2 14.4 31.5 12.5 36.5 34.2 26.3 19.3 16.8 87.7 37.4 40.5 37.8 34.8 49.4 73.0 73.6 45.7 41.1 31.5 51.0 48.2 92.4 23.2 50.6 54.2 43.4 48.4 63.9 54.0 61.8 26.4 67.0 22.8 62.7 48.6 67.7 53.7 37.2 40.7 40.6 40.7 46.7 65.1 21.8 49.0 41.4 72.2 38.3 81.5 137.8 60.0 74.9 46.2 54.4 46.0 71.4 81.8 83.6 34.2 63.3 38.0 90.7 59.2 33.9 38.2 80.4 61.0 57.0 63.4 45.8 82.1 42.8 69.8 79.7 51.7 96.1 45.7 1.8 16.6 17.1 7.5 23.4 5.7 9.6 9.2 9.0 24.4 7.5 6.6 6.5 13.4 12.6 27.9 9.1 17.1 10.1 15.0 13.7 14.0 14.1 13.4 13.7 14.2 14.2 13.9 13.4 14.4 16.8 6.7 6.4 13.3 70.8 19.1 27.8 17.2 10.3 17.6 15.3 10.6 6.3 4.7 12.8 9.3 11.0 16.7 13.3 9.0 8.3 1.9 4.9 3.6 5.2 9.1 11.3 13.1 18.3 115.0 2.6 10.5 9.6 11.2 8.7 10.1 10.2 14.3 14.0 10.1 11.8 111.2 7.0 8.2 19.2 18.4 3.0 13.1 15.2 12.4 100.2 21.8 4.6 14.4 106.1 134.4 7.5 8.3 8.6 11.2 19.7 8.5 2.4 8.8 10.5 6.6 12.5 6.0 12.2 6.4 26.9 16.6 16.6 12.8 7.9 10.4 16.8 MEP1A PPHA ENSG00000112818 "Meprin A subunit alpha" Q16819 6 46793389-46839778 "Enzymes, Plasma proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 101 "intestine: 467.7" "Cell type enhanced" "Detected in some" "Distal enterocytes: 309.4;Intestinal goblet cells: 87.0;Paneth cells: 156.9;Proximal enterocytes: 902.8" "Cancer enriched" "Detected in many" 5 "colorectal cancer: 38.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.3;CACO-2: 2.9;RPMI-8226: 1.2" "CAB025163, HPA029416" Enhanced NA NA 2100000 "Cluster 56: Intestine - Transmembrane transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" "CAB025163: , HPA029416: AB_10600823" "unprognostic (1.83e-1)" "unprognostic (2.81e-4)" "unprognostic (2.03e-1)" "unprognostic (8.53e-2)" "unprognostic (8.73e-2)" "unprognostic (1.13e-1)" "unprognostic (2.43e-2)" "unprognostic (5.27e-4)" "unprognostic (2.05e-1)" "unprognostic (2.35e-2)" "unprognostic (1.42e-1)" "unprognostic (2.11e-1)" "unprognostic (1.11e-3)" "unprognostic (1.45e-1)" "unprognostic (1.91e-2)" "unprognostic (4.70e-3)" "unprognostic (1.68e-1)" 0.2 0.0 0.0 4.6 0.0 0.0 0.1 0.0 0.1 0.0 0.0 115.6 269.9 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.0 4.2 0.0 0.0 0.5 0.1 0.1 102.5 0.0 0.0 0.2 0.0 0.0 467.7 2.6 0.0 0.1 0.5 0.7 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 309.4 0.0 0.0 7.7 0.1 0.0 0.0 15.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 87.0 0.0 0.0 0.0 6.9 0.0 0.2 0.0 3.7 0.0 0.0 0.0 0.5 0.3 0.0 156.9 0.4 0.0 0.0 902.8 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 45.8 0.0 MET "DFNB97, HGFR, RCCP2" ENSG00000105976 "MET proto-oncogene, receptor tyrosine kinase" P08581 7 116672196-116798377 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Deafness, Disease variant, FDA approved drug targets, Non-syndromic deafness, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 42.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 103.6;Club cells: 99.8;Glandular and luminal cells: 161.4;Pancreatic endocrine cells: 93.9;Prostatic glandular cells: 149.3;Urothelial cells: 128.6" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 5 "cerebral cortex: 7.5;hippocampal formation: 6.6;midbrain: 2.5;pons: 4.9;white matter: 7.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 203.8;CAPAN-2: 219.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB005282, CAB018577, HPA055607" Approved Approved "Plasma membrane,Cytosol" "Secreted to blood" NA NA 179000000 100000000 "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cytosol" "CAB005282: AB_631940, CAB018577: AB_649068, HPA055607: AB_2682860" "unprognostic (1.60e-2)" "unprognostic (7.71e-2)" "unprognostic (2.53e-2)" "unprognostic (1.58e-1)" "unprognostic (3.57e-3)" "prognostic unfavorable (6.75e-4)" "unprognostic (1.68e-1)" "unprognostic (3.22e-2)" "unprognostic (3.81e-2)" "unprognostic (2.52e-2)" "prognostic unfavorable (1.21e-7)" "unprognostic (1.86e-1)" "unprognostic (1.25e-1)" "unprognostic (5.53e-2)" "unprognostic (8.88e-2)" "unprognostic (2.01e-2)" "unprognostic (2.20e-1)" 10.3 0.8 0.1 3.4 0.6 7.4 8.9 0.1 7.5 13.1 9.6 9.7 6.5 6.4 2.5 6.1 4.7 11.9 6.2 6.6 0.8 20.1 42.9 20.3 2.3 1.1 2.5 0.8 6.6 0.8 3.8 26.4 4.9 6.7 9.3 3.9 8.7 11.2 14.3 7.7 8.2 5.7 0.3 6.0 15.4 0.5 0.5 3.7 17.6 11.0 3.2 18.4 4.4 7.8 203.8 115.3 0.1 0.6 8.6 8.7 7.9 113.7 48.2 60.3 51.1 25.0 219.0 8.4 179.0 72.1 163.3 51.8 19.7 110.0 123.7 0.3 23.4 0.1 112.5 21.4 1.5 0.3 0.2 11.4 42.4 40.6 129.1 109.4 42.4 0.2 4.5 0.8 114.1 5.0 0.1 0.1 17.3 32.9 113.0 0.2 95.3 0.2 105.8 24.0 16.5 0.0 45.4 15.4 44.9 19.8 0.4 0.9 72.3 89.7 30.6 46.7 88.9 2.5 19.1 1.5 99.3 0.3 12.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.1 7.5 6.6 0.8 1.1 2.5 4.9 0.3 0.5 7.8 32.6 28.9 103.6 0.3 1.0 39.0 70.5 58.1 38.1 6.7 6.5 6.9 12.3 11.5 99.8 31.3 0.0 76.0 0.4 20.5 0.0 38.5 0.0 52.5 11.6 20.1 7.2 0.0 2.6 46.9 7.5 7.4 32.6 161.4 0.0 0.0 3.9 30.5 7.0 0.0 1.0 20.5 18.3 1.3 2.2 0.1 0.6 4.4 3.6 1.9 1.0 7.6 0.0 0.5 7.7 93.9 5.5 0.0 0.4 149.3 11.2 15.6 34.5 0.3 0.0 37.8 5.2 0.0 0.6 7.9 17.8 21.8 1.2 0.0 16.4 128.6 METAP1 "KIAA0094, MAP1A, MetAP1A" ENSG00000164024 "Methionyl aminopeptidase 1" P53582 4 98995659-99062809 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Late spermatids: 1627.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025485, HPA037997, HPA037998" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 8900 "Cluster 44: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "Nucleoplasm, Plasma membrane" "CAB025485: , HPA037997: AB_2675777, HPA037998: AB_2675778" "unprognostic (1.79e-1)" "unprognostic (3.39e-1)" "prognostic favorable (7.22e-4)" "unprognostic (1.58e-2)" "unprognostic (6.53e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (3.08e-5)" "unprognostic (1.09e-1)" "unprognostic (1.51e-3)" "unprognostic (2.05e-1)" "prognostic unfavorable (2.28e-5)" "unprognostic (2.00e-1)" "prognostic favorable (1.72e-4)" "unprognostic (5.50e-2)" "unprognostic (8.51e-2)" "unprognostic (1.15e-3)" "prognostic favorable (9.31e-4)" 14.8 9.5 10.2 20.5 11.6 25.1 28.7 10.5 13.8 24.0 8.8 31.8 24.1 25.7 43.7 52.3 24.3 15.1 41.1 11.2 10.0 24.7 24.0 15.6 24.9 9.5 10.1 14.0 19.5 14.0 11.6 16.9 9.4 29.2 33.5 11.3 23.1 29.7 33.8 28.7 23.4 25.7 9.2 17.6 19.6 51.6 10.6 41.9 18.8 28.7 31.2 34.5 30.8 10.4 57.6 55.9 47.7 51.7 37.2 59.1 52.9 80.3 51.5 67.1 63.7 62.9 83.3 84.1 31.3 65.5 40.3 56.1 84.8 80.5 92.9 59.2 39.9 75.6 37.8 68.2 40.2 103.6 60.8 42.8 57.5 57.0 60.4 52.4 56.3 46.9 60.0 49.7 73.2 44.0 90.9 49.3 58.7 97.7 44.3 58.9 74.5 45.4 109.2 73.6 64.7 38.5 27.0 82.5 32.8 53.1 31.6 39.3 46.1 53.9 68.0 49.9 70.9 35.5 53.5 66.2 46.5 51.9 54.8 19.1 11.6 5.7 17.7 14.6 23.1 16.0 18.0 17.6 14.9 11.4 17.4 15.8 2.9 17.7 14.7 7.2 17.7 14.1 10.2 11.6 10.5 13.8 11.2 10.0 9.5 10.1 9.4 9.2 10.6 10.4 16.1 41.7 14.6 20.2 19.8 42.4 47.5 26.2 51.2 5.2 21.0 24.9 57.0 17.2 19.5 14.7 2.1 24.4 17.4 36.7 13.7 28.4 330.3 45.4 30.0 17.3 7.8 24.2 22.6 29.4 70.5 15.3 22.4 60.9 3.8 16.9 12.8 21.4 17.2 3.3 15.0 23.3 24.4 20.2 16.2 1627.3 19.3 17.4 16.0 14.0 13.9 10.6 25.7 17.6 22.3 28.0 30.8 22.6 17.8 34.4 25.3 31.6 17.2 3.7 26.3 11.5 21.7 15.7 41.6 54.3 38.8 7.7 23.6 18.1 36.2 46.9 METTL14 KIAA1627 ENSG00000145388 "Methyltransferase like 14" Q9HCE5 4 118685392-118715433 "Cancer-related genes, Metabolic proteins, Predicted intracellular proteins" "Differentiation, Spermatogenesis" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 96.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038002 Supported Supported Nucleoplasm Yes No "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 43: THP-1 - Innate immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm "HPA038002: AB_10672401" "unprognostic (4.48e-1)" "unprognostic (5.13e-2)" "unprognostic (5.98e-3)" "unprognostic (3.44e-2)" "unprognostic (1.33e-1)" "unprognostic (1.83e-1)" "unprognostic (3.75e-2)" "unprognostic (4.40e-1)" "unprognostic (9.97e-2)" "unprognostic (2.40e-2)" "unprognostic (3.64e-2)" "unprognostic (3.33e-3)" "prognostic favorable (1.46e-5)" "unprognostic (1.05e-1)" "unprognostic (1.32e-1)" "unprognostic (1.76e-3)" "unprognostic (7.76e-3)" 8.9 8.8 5.2 8.6 6.0 19.5 11.5 6.8 6.3 8.8 5.5 8.8 8.8 11.7 10.7 8.9 8.8 7.7 8.3 4.8 6.3 10.2 14.9 9.1 11.6 5.5 5.2 12.7 7.8 10.9 8.2 9.0 6.3 9.7 8.2 11.7 7.6 8.0 8.4 10.9 9.2 9.2 5.4 10.8 7.9 15.1 5.7 12.5 10.6 7.7 11.0 8.5 7.9 7.4 19.6 8.9 19.0 17.8 11.7 14.7 13.8 17.1 13.0 12.6 14.4 12.9 22.8 22.0 9.8 12.0 12.6 9.4 16.2 14.1 16.1 17.5 9.8 18.5 11.4 14.4 13.3 30.2 21.2 13.1 15.8 14.6 9.6 16.5 11.5 17.4 20.1 18.2 17.5 13.2 29.7 24.7 16.2 16.7 7.7 16.8 23.7 11.2 13.8 12.7 15.4 17.3 12.0 22.0 17.2 17.2 10.0 28.5 15.8 18.1 16.6 16.3 13.7 15.2 17.0 24.9 12.9 16.5 15.1 37.7 12.8 29.0 17.0 19.6 19.3 24.3 17.8 17.7 15.3 25.3 21.0 19.0 10.3 21.8 23.7 12.1 20.8 13.7 5.2 6.0 6.8 6.3 4.8 6.3 5.5 5.2 6.3 5.4 5.7 7.4 18.6 25.6 25.9 14.7 20.6 10.8 18.3 10.6 16.5 16.8 13.4 12.6 15.7 17.2 20.8 23.9 22.9 18.7 28.3 13.7 11.7 11.9 96.9 14.5 21.7 17.3 12.1 8.4 18.7 15.6 10.2 16.8 9.2 18.0 22.1 18.3 16.4 32.1 12.1 8.4 17.0 15.2 6.1 17.9 7.6 16.7 18.6 13.3 7.2 14.0 14.0 13.4 25.7 14.1 26.9 14.8 13.0 13.9 8.2 17.1 15.4 20.6 15.2 25.4 13.1 15.3 15.5 42.2 28.1 12.4 11.9 15.3 20.6 17.0 12.8 16.0 METTL23 "C17orf95, LOC124512" ENSG00000181038 "Methyltransferase like 23" Q86XA0 17 76726830-76733936 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 182.5;Spermatocytes: 198.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022889 Approved Vesicles No No "Cluster 15: NK-cells - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "HPA022889: " "unprognostic (5.45e-3)" "unprognostic (1.22e-1)" "unprognostic (1.35e-1)" "unprognostic (1.35e-1)" "unprognostic (7.70e-2)" "unprognostic (1.59e-1)" "prognostic unfavorable (4.18e-6)" "unprognostic (5.22e-2)" "unprognostic (1.76e-1)" "unprognostic (1.73e-2)" "unprognostic (1.03e-3)" "unprognostic (3.21e-2)" "prognostic unfavorable (3.93e-7)" "unprognostic (1.13e-2)" "unprognostic (1.82e-1)" "unprognostic (3.79e-1)" "unprognostic (3.65e-1)" 30.8 32.7 20.4 24.2 22.8 27.3 30.6 22.5 27.9 28.7 24.2 26.0 22.6 25.8 34.7 23.9 27.7 19.8 28.5 20.1 21.4 39.1 47.3 26.7 42.7 21.9 22.0 29.4 42.2 35.1 33.3 19.7 22.7 28.1 27.4 22.9 29.1 21.9 34.7 29.2 30.7 23.5 22.3 48.1 30.0 51.6 21.9 36.9 42.1 25.9 40.4 26.1 24.7 26.1 68.3 58.4 32.6 30.0 79.2 66.5 31.3 33.7 68.2 43.5 41.9 29.5 47.1 38.0 32.2 43.0 56.7 37.6 23.8 61.0 48.9 19.2 55.8 49.5 38.0 56.6 77.4 35.1 41.7 64.0 57.3 54.0 74.6 68.5 69.1 46.5 48.1 46.0 53.1 38.5 44.3 30.1 24.2 75.2 65.3 29.9 54.5 106.5 63.0 33.9 30.9 44.5 33.8 51.6 123.3 78.8 72.3 43.7 25.8 49.8 24.9 48.9 59.9 63.2 26.0 38.6 47.5 25.0 46.3 23.0 28.9 34.1 48.0 30.3 53.6 51.3 53.0 53.5 32.1 44.7 50.2 51.1 9.4 51.8 27.9 48.3 57.6 34.5 20.4 22.8 22.5 27.9 20.1 21.4 21.9 22.0 22.7 22.3 21.9 26.1 39.5 28.9 14.5 8.5 49.6 16.4 47.2 64.8 42.1 13.9 34.9 48.4 17.7 27.1 35.6 20.2 10.4 42.9 50.7 11.7 119.3 42.0 182.5 31.7 23.4 28.0 22.8 22.3 4.2 39.5 41.1 26.6 24.5 25.9 31.1 21.8 25.7 49.9 57.0 6.7 5.4 24.5 40.7 33.3 23.5 54.5 32.6 33.9 24.9 8.4 50.1 38.6 81.4 7.5 13.4 33.2 26.3 25.9 49.2 33.2 27.5 87.8 32.7 23.7 52.6 28.1 43.0 198.9 49.5 32.2 16.2 17.2 55.3 53.3 32.1 34.1 MEX3B "DKFZp434J0617, RKHD3, RNF195" ENSG00000183496 "Mex-3 RNA binding family member B" Q6ZN04 15 82041778-82046119 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "cervix: 14.0;testis: 46.8" "Group enriched" "Detected in many" 8 "Early spermatids: 204.7;Granulosa cells: 99.5;Late spermatids: 201.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 65.9;HEL: 49.2;SH-SY5Y: 26.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041093 Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 23: Testis - Cell cycle regulation" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Cytosol" "HPA041093: AB_10793868" "unprognostic (2.42e-1)" "unprognostic (1.76e-1)" "unprognostic (2.74e-2)" "unprognostic (6.84e-2)" "unprognostic (1.43e-1)" "unprognostic (1.64e-1)" "unprognostic (5.22e-2)" "unprognostic (7.56e-2)" "unprognostic (4.98e-2)" "unprognostic (1.18e-1)" "unprognostic (2.31e-1)" "unprognostic (9.31e-3)" "unprognostic (5.93e-8)" "unprognostic (1.24e-2)" "unprognostic (9.05e-2)" "unprognostic (4.09e-2)" "unprognostic (1.51e-2)" 2.2 0.4 1.7 1.5 1.6 2.0 1.5 2.8 2.8 14.0 0.0 3.4 0.6 6.2 0.5 0.9 1.3 2.5 2.7 1.8 0.7 0.7 0.9 1.5 2.7 0.7 0.9 5.6 0.6 0.2 0.8 2.3 0.7 2.5 0.7 0.8 2.6 3.2 1.6 1.1 1.1 1.4 0.3 1.1 1.0 46.8 1.9 6.4 0.8 2.0 1.0 1.4 4.1 1.0 0.2 2.5 17.2 65.9 1.4 2.0 4.9 2.1 1.0 3.6 3.2 0.5 0.4 3.2 1.2 3.9 1.1 0.5 8.2 0.3 2.5 0.7 5.3 49.2 2.8 2.2 2.8 0.6 15.1 1.0 1.3 2.0 4.0 8.4 7.6 6.1 2.4 0.0 6.2 1.6 8.3 4.2 22.4 0.1 0.6 11.4 10.4 1.7 0.1 0.0 13.7 26.2 3.5 0.6 2.4 4.8 0.2 0.8 6.9 9.0 10.3 5.0 3.1 6.1 3.4 3.7 2.9 5.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 1.6 2.8 2.8 1.8 0.7 0.7 0.9 0.7 0.3 1.9 1.0 3.6 0.0 0.6 0.0 1.3 2.8 0.4 1.4 5.2 3.1 6.0 8.0 4.5 1.5 0.4 0.0 2.1 11.3 1.6 0.7 0.0 0.8 204.7 1.8 13.5 5.3 1.2 7.2 2.1 0.2 8.7 8.3 0.5 1.3 1.3 99.5 2.5 0.2 1.5 0.0 3.4 1.0 0.0 1.0 9.8 201.1 6.5 5.0 7.2 1.0 0.5 5.2 0.0 4.0 1.3 0.5 0.2 4.5 0.8 0.8 0.0 0.0 0.3 2.9 6.6 1.9 16.8 2.7 18.8 5.8 2.0 2.5 2.0 1.0 1.4 0.2 MFAP1 AMP ENSG00000140259 "Microfibril associated protein 1" P55081 15 43804492-43824690 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 147.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015583, HPA042370" Uncertain Supported Nucleoplasm,Centrosome NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Centrosome "HPA015583: , HPA042370: AB_10796904" "unprognostic (1.05e-1)" "unprognostic (5.94e-2)" "unprognostic (2.56e-2)" "unprognostic (1.23e-2)" "unprognostic (2.06e-1)" "unprognostic (5.28e-2)" "prognostic unfavorable (2.50e-4)" "unprognostic (4.08e-1)" "unprognostic (1.48e-1)" "unprognostic (1.66e-2)" "unprognostic (3.12e-1)" "unprognostic (7.02e-2)" "prognostic favorable (1.04e-9)" "unprognostic (1.66e-2)" "unprognostic (9.68e-2)" "unprognostic (3.82e-3)" "unprognostic (1.54e-2)" 15.9 24.0 17.5 17.6 18.0 12.9 21.4 21.3 23.2 16.6 19.7 17.1 14.5 18.8 23.4 22.2 18.4 14.9 22.1 17.7 19.3 23.7 18.1 15.2 26.6 18.3 19.3 24.8 15.3 33.2 14.5 23.2 18.7 22.8 18.1 25.0 17.0 17.7 26.3 20.5 15.0 19.1 17.7 17.1 16.8 19.3 18.5 24.4 24.7 23.2 32.4 20.6 17.5 19.1 40.1 41.0 69.4 46.0 57.9 36.3 42.7 63.1 43.8 50.3 58.2 64.1 25.6 42.8 58.7 39.4 50.9 70.8 62.5 51.7 58.9 72.9 37.6 103.7 71.6 48.5 45.4 62.3 53.2 34.1 55.3 48.0 43.3 48.0 49.8 48.3 95.8 35.7 60.9 30.0 51.1 47.0 49.2 74.2 35.4 73.9 69.6 27.6 52.0 59.0 43.8 43.0 55.6 47.0 27.0 55.2 70.7 39.5 47.4 50.6 35.8 56.3 51.7 43.5 112.2 91.8 42.5 58.4 37.9 42.5 25.5 56.9 35.3 34.8 34.7 35.0 35.1 33.6 32.6 28.3 35.7 35.0 22.6 50.5 29.1 26.8 44.1 26.3 17.5 18.0 21.3 23.2 17.7 19.3 18.3 19.3 18.7 17.7 18.5 19.1 30.4 35.3 30.2 5.2 32.8 30.3 59.6 50.1 35.9 41.8 22.4 28.8 31.0 25.8 43.2 51.5 6.2 94.6 33.2 27.4 56.7 44.2 6.2 43.1 39.9 35.6 11.3 32.0 9.0 29.4 55.0 29.8 21.4 39.4 46.3 37.6 20.7 18.8 35.4 32.0 8.6 24.4 38.7 20.7 20.5 6.3 28.0 25.5 26.6 5.6 30.6 51.5 33.0 2.0 8.2 26.8 27.1 35.7 20.6 39.3 22.1 42.9 60.0 35.2 19.7 35.9 41.7 49.7 84.8 28.1 27.7 147.4 33.6 39.4 21.3 50.6 MGAT4B GnT-Ivb ENSG00000161013 "Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B" Q9UQ53 5 179797597-179806952 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 277.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 224.7;Proximal enterocytes: 224.5;Undifferentiated cells: 131.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "eosinophil: 5.5" "Lineage enriched" "Detected in single" 6 "granulocytes: 5.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012804, HPA052134" Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles,Cytosol" "Intracellular and membrane" NA NA 19000 "Cluster 52: Eosinophils - Transcription" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 45: Enterocytes - Digestion" Nucleoplasm "Golgi apparatus, Vesicles, Cytosol" "HPA012804: , HPA052134: AB_2681741" "unprognostic (2.01e-2)" "unprognostic (8.68e-3)" "unprognostic (1.40e-1)" "unprognostic (3.83e-2)" "prognostic unfavorable (6.15e-5)" "unprognostic (3.61e-3)" "unprognostic (7.57e-3)" "unprognostic (1.22e-2)" "unprognostic (2.02e-1)" "unprognostic (5.13e-2)" "unprognostic (2.26e-2)" "unprognostic (2.27e-2)" "prognostic favorable (5.78e-4)" "unprognostic (1.52e-1)" "unprognostic (2.54e-1)" "unprognostic (1.72e-2)" "unprognostic (1.42e-1)" 48.4 105.0 17.2 19.0 16.9 24.6 39.9 16.8 19.3 37.0 18.1 147.0 134.1 36.9 13.4 75.1 37.2 23.5 103.3 18.9 14.2 124.8 277.1 61.2 15.5 16.3 15.0 41.1 63.3 22.9 37.7 17.9 15.1 42.3 65.0 4.4 57.9 11.9 43.8 53.4 168.3 14.9 14.6 52.8 96.3 30.6 18.0 10.5 60.1 14.9 16.0 38.7 42.1 16.2 84.2 85.3 40.8 93.7 117.4 65.1 71.1 48.3 98.3 44.4 34.8 91.7 226.4 14.4 122.3 108.2 193.1 61.6 57.9 110.1 32.2 121.0 33.0 43.5 75.1 78.4 85.9 53.7 13.4 70.5 76.6 44.1 53.0 165.2 89.1 16.9 28.7 38.5 73.6 92.6 8.4 47.4 24.7 123.7 35.1 21.6 31.4 40.4 132.3 158.5 67.5 39.7 73.7 75.2 139.1 33.8 51.3 56.3 109.2 106.6 48.6 61.2 80.2 32.5 39.5 35.4 125.0 68.2 78.7 0.0 0.4 5.5 0.1 0.1 0.0 0.0 0.3 0.1 0.3 0.9 0.2 0.3 0.1 0.0 0.3 0.3 0.0 0.2 17.2 16.9 16.8 19.3 18.9 14.2 16.3 15.0 15.1 14.6 18.0 16.2 35.7 12.8 9.2 9.4 7.7 12.5 17.8 12.5 5.2 15.5 29.6 30.7 24.1 37.1 11.1 27.6 4.2 8.1 22.1 224.7 3.9 66.7 0.7 27.2 17.8 24.3 22.9 5.5 11.4 54.0 11.1 15.3 78.5 50.5 5.1 39.5 26.7 89.9 17.7 30.3 10.0 72.2 14.2 20.7 11.7 2.6 15.2 24.5 10.6 9.4 16.8 25.7 6.2 4.5 6.3 89.9 114.6 17.0 7.0 49.0 224.5 22.4 7.7 11.1 13.1 16.2 24.7 1.5 6.5 21.1 11.9 14.0 12.5 24.9 131.8 64.8 MIXL1 "MILD1, MIXL" ENSG00000185155 "Mix paired-like homeobox" Q9H2W2 1 226223618-226227060 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 3.4" "Cell type enriched" "Detected in some" 5 "Plasma cells: 18.5" "Cancer enriched" "Detected in some" 9 "testis cancer: 6.3" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HAP1: 1.7;Hep G2: 9.0;SuSa: 1.9;U-698: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA005662 Approved Nucleoplasm NA NA "Cluster 42: Non-specific - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 55: Plasma cells - Humoral immune response" Nucleoplasm "HPA005662: AB_2667382" "unprognostic (4.09e-2)" "unprognostic (2.84e-2)" "unprognostic (2.15e-2)" "unprognostic (1.00e-1)" "unprognostic (6.34e-2)" "unprognostic (1.03e-2)" "unprognostic (3.18e-2)" "unprognostic (5.66e-2)" "unprognostic (5.05e-2)" "unprognostic (7.40e-3)" "unprognostic (2.78e-2)" "unprognostic (2.70e-1)" "unprognostic (2.71e-13)" "unprognostic (1.54e-1)" "unprognostic (1.29e-2)" "unprognostic (1.67e-1)" "unprognostic (8.47e-2)" 0.1 0.1 0.3 1.0 0.2 0.2 0.2 1.2 0.3 0.1 0.2 0.7 1.3 0.2 0.1 0.0 0.0 0.1 0.2 0.2 0.2 0.0 0.1 0.2 2.4 0.3 0.2 0.2 0.1 0.6 0.0 0.2 0.3 0.1 0.6 0.1 0.2 0.2 0.0 0.2 0.7 0.1 0.1 1.0 0.8 0.4 0.2 0.2 0.1 0.0 3.4 0.6 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.0 0.0 1.7 0.0 0.1 0.0 0.1 0.1 0.2 9.0 0.4 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.1 1.2 0.0 0.1 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 1.9 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.2 0.0 2.4 0.0 0.0 0.0 49.7 6.5 13.0 6.4 10.0 12.6 11.3 7.3 7.3 7.2 10.4 9.6 9.7 18.2 19.6 19.5 11.0 10.3 6.2 0.3 0.2 1.2 0.3 0.2 0.2 0.3 0.2 0.3 0.1 0.2 0.4 0.6 0.0 0.0 0.0 3.2 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.0 0.3 0.2 0.1 1.1 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.3 0.0 1.8 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 18.5 0.1 0.1 0.1 0.0 0.5 0.0 0.3 0.1 0.1 1.5 0.0 0.0 0.3 0.1 0.1 0.0 0.1 MLKL FLJ34389 ENSG00000168404 "Mixed lineage kinase domain like pseudokinase" Q8NB16 16 74671855-74700960 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Transporters" Necrosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 32.1;Endothelial cells: 25.9;granulocytes: 29.1;Macrophages: 28.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA078638 Supported "Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" "Cell Junctions, Cytosol" "HPA078638: " "unprognostic (7.53e-2)" "unprognostic (1.74e-2)" "unprognostic (2.57e-1)" "prognostic favorable (2.16e-4)" "unprognostic (1.23e-1)" "unprognostic (3.07e-1)" "unprognostic (5.69e-2)" "unprognostic (3.67e-3)" "unprognostic (1.90e-1)" "unprognostic (6.64e-3)" "unprognostic (1.37e-1)" "unprognostic (2.74e-1)" "unprognostic (1.60e-3)" "unprognostic (5.30e-2)" "unprognostic (1.26e-2)" "unprognostic (1.06e-1)" "unprognostic (1.53e-3)" 20.0 7.1 8.4 20.3 8.7 30.7 12.1 8.6 12.7 9.0 9.6 11.0 11.0 6.0 2.0 15.6 8.0 11.5 10.6 7.8 8.2 15.4 9.3 25.6 15.4 10.1 9.8 3.0 9.9 1.6 3.7 9.2 9.3 8.4 11.4 0.3 13.3 4.3 3.1 4.9 14.4 7.6 9.1 36.1 10.8 1.2 10.3 6.7 8.7 3.1 13.8 12.3 11.5 9.6 13.5 24.4 0.1 0.1 6.0 12.4 0.2 17.0 14.8 15.4 22.4 13.9 26.6 0.3 19.1 14.2 13.7 21.7 4.3 24.9 5.8 8.3 0.6 18.8 17.6 16.2 4.2 12.3 18.6 8.5 2.4 16.8 5.7 9.0 37.3 21.3 2.7 2.5 11.9 22.0 7.0 24.3 2.2 29.3 30.0 13.5 1.8 23.8 22.0 10.2 1.0 0.8 13.4 8.7 7.2 0.1 6.2 12.5 41.4 7.8 4.8 7.0 11.7 11.2 40.2 3.2 13.7 42.3 3.9 21.9 36.2 45.8 11.2 22.2 15.4 8.1 12.6 12.0 18.9 6.7 6.8 10.4 48.6 3.6 23.3 1.2 17.4 16.0 8.4 8.7 8.6 12.7 7.8 8.2 10.1 9.8 9.3 9.1 10.3 9.6 32.1 3.2 10.7 1.0 9.8 3.4 6.8 3.1 7.4 0.2 3.3 3.4 3.1 2.8 5.5 1.8 0.0 0.2 9.6 8.9 1.9 4.6 3.5 1.2 1.9 25.9 1.2 3.4 0.5 5.2 0.8 7.1 15.3 1.6 29.1 0.3 16.8 1.3 16.6 1.7 0.5 10.9 0.0 18.2 7.8 5.2 0.9 28.9 7.2 11.2 16.7 0.1 11.3 1.5 5.2 4.9 9.4 0.4 18.5 2.8 5.5 0.6 2.0 0.6 0.0 3.0 3.1 0.1 0.2 13.4 2.8 0.3 16.5 0.2 9.5 7.5 MMACHC "cblC, DKFZP564I122" ENSG00000132763 "Metabolism of cobalamin associated C" Q9Y4U1 1 45500300-45513382 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Oxidoreductase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 17.4" "Cell type enhanced" "Detected in many" "Hepatocytes: 22.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027394, HPA027399, HPA027402" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" Nucleoplasm "Plasma membrane, Cytosol" "HPA027394: AB_10601669, HPA027399: AB_10601987, HPA027402: AB_2672255" "unprognostic (3.34e-1)" "unprognostic (1.63e-1)" "unprognostic (7.03e-3)" "unprognostic (3.14e-2)" "unprognostic (4.05e-1)" "unprognostic (1.16e-2)" "unprognostic (9.04e-2)" "unprognostic (1.03e-2)" "unprognostic (1.90e-1)" "unprognostic (1.05e-2)" "unprognostic (3.88e-2)" "unprognostic (6.81e-2)" "unprognostic (2.61e-3)" "unprognostic (2.08e-3)" "unprognostic (8.83e-2)" "unprognostic (2.50e-2)" "unprognostic (2.58e-2)" 2.0 3.1 3.3 1.7 5.3 1.2 3.5 5.1 4.2 2.9 2.3 3.7 3.3 1.7 3.0 2.8 3.5 1.3 6.9 3.4 5.1 3.5 17.4 1.2 1.8 4.1 5.6 3.5 2.9 5.5 1.3 1.5 3.9 2.0 4.4 2.1 5.0 2.4 10.8 2.0 2.4 2.3 3.5 1.6 2.3 4.3 5.6 2.2 2.3 6.6 2.0 1.7 1.5 6.0 7.7 3.9 6.6 10.0 6.1 3.7 8.1 5.9 3.9 10.5 9.4 8.3 4.7 12.0 7.4 4.9 2.0 6.2 12.3 14.0 9.6 3.3 11.4 9.4 6.5 9.2 5.8 13.5 3.3 5.3 7.8 11.6 12.6 3.7 5.1 12.5 10.8 6.7 8.1 8.2 9.1 4.3 10.9 8.8 8.9 11.1 2.7 13.2 6.2 6.0 10.5 5.4 8.8 14.5 19.3 4.9 8.3 4.6 2.3 7.3 9.9 8.3 3.3 9.9 8.5 6.9 5.3 6.4 6.9 2.3 0.5 0.5 0.5 0.8 0.8 0.7 0.7 0.4 0.6 0.6 1.3 0.6 0.9 0.8 2.7 1.3 0.4 0.4 3.3 5.3 5.1 4.2 3.4 5.1 4.1 5.6 3.9 3.5 5.6 6.0 1.1 3.2 5.5 1.6 2.1 0.1 1.8 0.8 5.7 1.3 2.7 1.5 9.8 4.3 2.2 1.8 0.0 3.7 0.6 2.8 5.9 1.3 1.0 3.6 4.8 1.5 4.2 4.8 2.6 1.4 4.3 3.6 7.1 3.2 2.5 2.9 2.5 22.9 3.3 3.3 2.7 3.2 2.0 3.2 0.9 1.2 1.8 2.7 0.0 0.0 0.6 1.4 3.1 1.5 5.3 1.8 2.3 1.5 10.4 1.7 2.0 4.6 1.2 5.2 0.0 5.0 2.4 7.4 2.1 11.5 0.1 2.7 2.4 3.9 5.8 1.8 MPEG1 MPG1 ENSG00000197629 "Macrophage expressed 1" Q2M385 11 59208510-59212927 "Predicted membrane proteins, Predicted secreted proteins, Transporters" "Immunity, Innate immunity" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 207.4" "Group enriched" "Detected in some" 4 "dendritic cells: 156.0;Kupffer cells: 409.8;Macrophages: 174.6;monocytes: 218.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 290.5;intermediate monocyte: 209.9;myeloid DC: 144.7;non-classical monocyte: 245.2;plasmacytoid DC: 204.9" "Group enriched" "Detected in many" 6 "dendritic cells: 204.9;monocytes: 290.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA046801 Approved "Secreted to blood" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA046801: AB_2679814" "unprognostic (1.24e-1)" "unprognostic (2.17e-3)" "unprognostic (1.05e-2)" "unprognostic (2.00e-2)" "unprognostic (3.38e-2)" "unprognostic (2.79e-3)" "unprognostic (7.82e-2)" "unprognostic (1.41e-2)" "unprognostic (6.23e-2)" "unprognostic (2.76e-1)" "unprognostic (5.48e-2)" "unprognostic (3.51e-1)" "unprognostic (1.48e-1)" "unprognostic (9.38e-2)" "unprognostic (2.48e-2)" "unprognostic (1.76e-1)" "unprognostic (5.86e-2)" 29.2 15.8 1.5 112.4 1.6 21.3 13.5 1.7 2.4 11.6 3.2 32.9 40.9 10.9 3.7 12.6 6.9 36.2 10.3 1.4 2.1 6.0 41.1 35.4 96.3 3.3 1.9 4.9 4.6 4.6 1.6 35.8 2.5 8.0 43.4 0.3 7.3 9.3 3.9 7.1 52.8 28.2 2.9 207.4 19.2 4.5 4.0 42.8 5.9 8.3 75.2 42.7 2.1 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.4 290.5 8.4 0.5 209.9 0.5 12.6 0.3 0.2 144.7 14.0 0.2 0.1 38.5 1.2 245.2 204.9 0.6 214.5 1.5 1.6 1.7 2.4 1.4 2.1 3.3 1.9 2.5 2.9 4.0 4.0 0.7 0.0 7.9 0.0 33.8 1.1 0.0 0.0 1.2 0.0 0.3 0.9 1.7 1.5 0.6 0.0 0.0 0.3 156.0 0.1 0.0 0.0 0.2 0.0 0.1 1.7 0.0 4.4 0.0 0.0 0.6 0.8 0.5 0.1 2.5 0.0 4.6 3.7 52.4 0.0 0.0 0.0 0.0 409.8 48.0 0.6 0.0 174.6 1.8 10.3 218.2 0.2 7.2 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.7 0.7 0.1 6.6 0.7 0.4 0.0 0.0 0.3 1.6 0.3 2.7 0.0 0.0 0.1 MPI ENSG00000178802 "Mannose phosphate isomerase" P34949 15 74890005-74902219 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Isomerase "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 70.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007200 Approved Approved "Plasma membrane,Cytosol" NA NA 350000 "Cluster 20: T-cells - T-cell receptor" "Cluster 39: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 45: Enterocytes - Digestion" Cytosol "Plasma membrane" "HPA007200: AB_1854079" "unprognostic (1.38e-1)" "unprognostic (7.18e-2)" "unprognostic (1.63e-1)" "unprognostic (1.65e-3)" "unprognostic (7.34e-2)" "prognostic unfavorable (2.39e-4)" "unprognostic (1.79e-1)" "unprognostic (2.76e-1)" "unprognostic (3.20e-1)" "unprognostic (2.93e-2)" "unprognostic (1.47e-1)" "unprognostic (1.27e-1)" "unprognostic (3.34e-2)" "unprognostic (2.11e-1)" "unprognostic (1.15e-1)" "unprognostic (2.09e-1)" "unprognostic (6.58e-2)" 18.9 50.5 45.4 16.7 47.3 11.7 20.1 52.2 49.2 23.9 41.1 31.8 45.6 23.6 35.3 27.7 27.8 16.0 44.8 46.6 47.9 31.2 39.1 14.9 20.9 55.5 50.1 30.6 31.8 31.1 22.9 16.2 56.2 27.5 31.4 33.6 23.7 22.9 52.2 16.5 33.0 22.5 45.7 23.0 20.9 26.2 50.0 23.2 23.2 70.9 24.2 24.2 19.5 47.1 27.2 36.9 29.8 34.0 66.7 32.2 26.0 22.8 37.2 38.4 53.4 36.7 35.0 38.3 48.6 33.6 30.6 65.9 60.0 66.7 36.2 29.4 74.9 68.8 35.3 39.9 47.5 32.0 19.4 43.1 16.9 36.2 64.4 58.1 52.9 45.2 23.4 30.7 50.1 23.2 34.6 14.2 16.4 40.9 31.0 35.0 28.0 94.9 45.5 30.4 55.7 24.4 26.7 47.5 28.7 43.5 65.3 21.9 24.1 22.9 19.4 17.3 22.6 75.0 48.4 25.1 47.9 45.8 17.1 2.3 16.2 5.7 28.2 17.0 37.0 27.4 38.3 32.6 23.0 31.9 56.0 40.8 2.7 43.1 15.5 19.1 53.1 29.0 45.4 47.3 52.2 49.2 46.6 47.9 55.5 50.1 56.2 45.7 50.0 47.1 5.6 6.4 15.0 7.8 10.8 1.9 7.6 16.4 5.2 23.4 9.2 10.7 54.1 7.2 10.9 14.7 4.2 31.8 9.1 28.3 15.6 19.6 18.9 5.6 9.2 9.6 10.8 4.2 4.9 8.8 11.4 10.9 6.1 8.5 15.2 13.3 6.1 18.8 23.9 35.3 6.1 19.0 8.2 7.2 2.2 31.3 11.1 6.6 3.6 3.7 9.7 20.7 12.3 2.0 6.9 12.2 33.2 8.6 11.8 7.2 70.1 31.4 7.8 16.7 6.6 8.2 10.1 34.5 9.0 9.1 2.7 16.3 11.1 21.0 16.4 6.2 MPP6 "p55T, PALS2, VAM-1" ENSG00000105926 "Membrane palmitoylated protein 6" Q9NZW5 7 24573268-24694193 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.1;testis: 25.0" "Cell type enhanced" "Detected in many" "Astrocytes: 74.1;Excitatory neurons: 140.1;Inhibitory neurons: 146.6;Spermatocytes: 71.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 8.3" "Group enriched" "Detected in many" 4 "B-cells: 8.3;dendritic cells: 2.9;T-cells: 2.3" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019085, HPA020456" Enhanced NA NA "Cluster 37: B-cells - Transcription" "Cluster 78: Testis - Spermatogenesis" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA019085: AB_1858713, HPA020456: AB_1858714" "unprognostic (2.79e-1)" "unprognostic (3.49e-1)" "unprognostic (7.84e-2)" "prognostic unfavorable (1.46e-4)" "unprognostic (1.10e-2)" "prognostic unfavorable (8.85e-5)" "unprognostic (2.18e-3)" "unprognostic (3.80e-2)" "unprognostic (4.07e-2)" "unprognostic (2.84e-1)" "unprognostic (1.29e-2)" "unprognostic (2.69e-1)" "prognostic favorable (3.05e-5)" "unprognostic (1.94e-1)" "unprognostic (8.51e-2)" "prognostic unfavorable (5.28e-4)" "unprognostic (1.88e-3)" 3.8 2.7 10.0 3.4 16.0 3.1 4.1 3.9 14.2 1.7 0.0 1.6 3.5 1.9 1.1 3.0 2.6 19.1 1.6 20.0 24.1 8.6 9.4 1.9 4.9 10.2 17.2 9.4 7.7 0.4 1.5 0.8 8.5 2.6 1.4 2.5 2.8 1.2 9.2 2.3 4.5 3.1 9.5 2.0 2.5 25.0 20.8 4.3 6.0 3.2 4.9 1.9 2.9 12.8 24.4 14.2 15.2 22.7 16.6 11.8 11.1 18.1 10.0 12.3 15.5 42.6 18.1 43.1 14.4 11.1 32.1 15.0 26.7 21.6 24.4 17.1 21.5 7.1 23.6 10.4 12.9 29.2 5.0 12.3 9.1 14.7 26.1 9.0 19.6 25.3 46.7 16.5 14.3 9.7 18.9 7.7 83.9 11.5 22.6 22.9 26.5 23.1 17.2 33.1 11.8 48.4 20.8 20.4 6.3 30.3 10.3 4.2 18.8 8.0 33.7 25.0 34.8 62.4 6.8 83.8 14.3 10.9 30.1 0.2 0.1 0.1 1.9 0.8 1.2 5.7 0.9 2.2 0.2 8.3 2.3 2.0 0.2 1.0 0.0 2.9 0.8 0.4 10.0 16.0 3.9 14.2 20.0 24.1 10.2 17.2 8.5 9.5 20.8 12.8 0.8 6.4 3.2 74.1 16.9 11.1 16.2 6.3 15.9 2.5 13.0 8.5 5.6 47.1 5.0 5.5 43.8 2.9 8.3 0.8 3.9 36.2 31.9 1.3 9.5 3.0 3.0 8.0 140.1 18.0 2.1 13.2 3.6 3.3 0.0 53.3 2.9 16.0 1.4 3.3 146.6 9.2 2.0 1.8 2.9 30.1 5.3 1.8 1.8 8.4 1.6 1.8 3.1 30.7 4.2 12.6 25.0 7.2 9.7 20.5 26.3 31.0 1.0 5.9 0.0 34.7 16.0 71.7 24.1 9.4 8.8 0.5 10.9 6.8 6.3 10.2 MPZL2 "EVA, EVA1" ENSG00000149573 "Myelin protein zero like 2" O60487 11 118253416-118264536 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Cell adhesion" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 222.5;urinary bladder: 155.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 332.5;Basal prostatic cells: 504.4;Basal respiratory cells: 289.1;Squamous epithelial cells: 336.4;Suprabasal keratinocytes: 467.4;Urothelial cells: 489.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 11.6;intermediate monocyte: 9.2;myeloid DC: 17.0;neutrophil: 13.2" "Group enriched" "Detected in many" 10 "dendritic cells: 17.0;granulocytes: 13.2;monocytes: 11.6" "Cell line enhanced" "Detected in some" "CAPAN-2: 120.9;EFO-21: 130.4;HaCaT: 166.9;RT4: 321.7;TIME: 351.9" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 5 "spinal cord: 38.8" HPA060740 Approved Approved "Cell Junctions" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "Cell Junctions" "HPA060740: AB_2684352" "unprognostic (1.74e-1)" "unprognostic (6.02e-2)" "unprognostic (8.23e-2)" "unprognostic (3.28e-3)" "unprognostic (9.95e-3)" "unprognostic (1.56e-1)" "unprognostic (2.11e-3)" "unprognostic (3.58e-1)" "unprognostic (7.39e-2)" "unprognostic (5.45e-2)" "prognostic unfavorable (1.14e-4)" "unprognostic (1.91e-1)" "unprognostic (3.91e-2)" "unprognostic (3.07e-2)" "unprognostic (1.80e-1)" "prognostic favorable (1.62e-4)" "unprognostic (2.08e-2)" 28.6 4.7 2.5 11.9 2.1 0.7 19.6 2.3 4.8 56.7 5.2 31.1 17.0 16.9 38.5 222.5 46.4 33.5 7.2 2.3 2.6 26.4 23.2 47.0 2.3 3.2 3.0 3.8 13.5 27.1 10.7 1.7 3.2 48.6 30.8 0.9 58.0 69.5 4.7 38.8 11.3 14.7 3.6 4.6 37.0 0.9 3.4 18.1 30.3 1.0 52.6 155.9 120.5 2.8 65.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 27.0 120.9 0.3 130.4 0.0 0.6 166.9 0.0 38.9 0.0 0.2 9.5 0.1 1.7 35.8 0.0 0.0 0.4 0.0 90.2 0.0 3.0 0.0 86.8 0.8 0.0 0.2 0.0 51.3 0.2 0.2 1.6 34.2 0.1 0.0 0.0 6.4 14.9 321.7 0.1 0.0 5.8 61.4 0.0 0.5 26.1 0.7 351.9 0.1 0.2 0.0 0.1 0.1 0.2 0.2 0.1 0.0 0.0 2.3 11.6 3.0 0.1 9.2 1.3 0.0 0.6 0.4 17.0 0.0 0.8 0.9 13.2 0.4 1.4 0.3 0.2 3.8 2.5 2.1 2.3 4.8 2.3 2.6 3.2 3.0 3.2 3.6 3.4 2.8 5.9 83.3 123.3 0.0 0.2 332.5 504.4 289.1 127.5 0.0 29.0 17.4 3.4 30.0 221.1 128.8 0.0 1.7 0.5 52.0 0.0 39.4 0.0 91.6 18.8 33.6 5.3 3.6 0.0 51.1 0.2 8.2 29.6 194.0 7.0 0.0 45.3 16.5 0.8 0.0 0.0 6.3 81.4 6.4 27.0 0.3 0.0 7.8 21.4 1.9 4.9 0.0 1.0 0.0 0.0 68.2 20.8 0.0 1.2 186.3 3.3 6.9 65.2 0.0 0.0 0.3 9.2 0.2 0.7 336.4 467.4 17.8 5.4 0.0 33.4 489.7 MROH7 "C1orf175, FLJ46354, HEATR8" ENSG00000184313 "Maestro heat like repeat family member 7" Q68CQ1 1 54641754-54710266 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "testis: 55.5" "Group enriched" "Detected in some" 57 "Early spermatids: 179.0;Late spermatids: 546.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA071840 Enhanced NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 25: Spermatids - Spermatogenesis" "HPA071840: AB_2732187" "unprognostic (1.52e-3)" "unprognostic (1.51e-3)" "unprognostic (1.65e-2)" "unprognostic (2.77e-4)" "unprognostic (1.81e-1)" "unprognostic (9.88e-4)" "unprognostic (1.09e-1)" "unprognostic (2.84e-1)" "unprognostic (1.84e-1)" "unprognostic (2.11e-1)" "unprognostic (4.16e-2)" "unprognostic (1.79e-2)" "unprognostic (7.93e-2)" "unprognostic (7.40e-3)" "unprognostic (2.38e-1)" "unprognostic (5.83e-2)" "unprognostic (4.15e-2)" 0.2 0.6 2.2 0.0 2.5 0.7 0.2 2.9 2.8 0.7 7.0 3.1 0.1 1.1 1.0 0.6 1.3 0.2 2.7 2.3 2.4 2.3 1.1 0.4 0.1 2.9 3.1 2.9 0.3 0.5 4.3 0.0 2.6 2.3 0.3 0.5 1.8 0.7 0.7 1.0 1.4 0.1 2.5 0.2 1.7 55.5 3.2 0.0 5.3 0.2 0.0 1.8 0.8 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 2.5 2.9 2.8 2.3 2.4 2.9 3.1 2.6 2.5 3.2 2.5 0.0 0.0 1.3 0.0 0.2 0.9 0.9 0.1 0.0 1.7 0.3 0.5 4.0 0.0 1.4 0.0 0.0 0.0 0.0 4.0 0.0 0.1 179.0 1.1 0.2 0.3 2.4 0.0 0.0 0.4 0.0 0.2 0.0 1.2 5.1 0.3 0.4 0.3 0.4 0.0 0.0 3.0 0.0 1.0 0.7 546.1 4.4 0.5 0.0 0.0 0.7 2.5 0.0 0.0 0.0 0.1 6.1 4.5 0.0 0.3 5.0 0.2 1.0 0.4 0.0 1.9 0.2 6.3 2.8 0.0 0.4 0.1 0.2 0.5 2.2 1.1 MRPL16 "FLJ20484, PNAS-111" ENSG00000166902 "Mitochondrial ribosomal protein L16" Q9NX20 11 59806140-59810778 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 248.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054133 Supported NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 39: Non-specific - Basic cellular processes" "HPA054133: AB_2682394" "prognostic favorable (1.04e-4)" "unprognostic (1.13e-1)" "unprognostic (3.45e-3)" "unprognostic (5.88e-2)" "unprognostic (2.08e-1)" "unprognostic (5.40e-2)" "unprognostic (1.78e-1)" "unprognostic (1.59e-1)" "unprognostic (1.20e-1)" "unprognostic (2.40e-3)" "unprognostic (1.50e-3)" "unprognostic (2.67e-2)" "unprognostic (2.87e-3)" "unprognostic (3.01e-2)" "unprognostic (1.23e-1)" "unprognostic (6.38e-2)" "unprognostic (2.01e-2)" 35.2 61.4 44.1 29.6 44.7 57.0 34.6 45.6 54.7 30.4 45.4 49.7 42.1 32.7 23.1 33.7 29.0 20.6 85.7 44.2 45.3 51.2 78.3 25.6 44.3 43.4 44.0 31.5 38.6 56.1 23.0 29.8 43.8 25.3 48.3 21.4 43.2 28.8 85.8 24.6 34.7 36.3 44.5 41.6 44.3 34.1 45.3 50.7 20.7 103.5 46.0 29.4 25.7 44.8 76.3 75.4 53.4 50.1 74.9 59.1 48.0 52.1 68.9 93.9 80.1 75.1 79.5 174.0 87.0 68.2 50.3 72.8 178.0 96.9 84.0 58.9 89.5 92.7 69.9 89.5 57.8 139.4 55.1 71.1 52.4 78.8 56.4 54.5 92.4 112.6 278.4 51.2 70.9 150.6 97.8 224.1 84.1 89.8 124.2 85.4 78.6 91.1 137.2 103.3 50.2 34.9 83.4 83.8 134.3 49.4 100.1 132.0 46.3 36.9 50.7 77.4 63.7 57.9 69.8 240.7 44.9 88.1 40.8 80.8 95.1 72.9 87.4 118.1 91.0 118.7 96.5 91.5 116.1 121.2 102.8 91.4 18.1 116.8 94.5 166.9 108.2 149.7 44.1 44.7 45.6 54.7 44.2 45.3 43.4 44.0 43.8 44.5 45.3 44.8 44.3 48.1 31.4 10.4 43.6 31.9 19.7 87.9 34.1 9.9 29.4 47.0 146.1 31.5 42.6 42.3 12.5 94.2 45.9 35.5 248.4 47.9 18.0 28.5 41.5 41.0 34.1 64.8 9.0 53.4 74.1 46.7 46.9 28.5 61.4 104.6 35.7 73.6 75.3 8.4 10.9 67.7 46.8 45.6 24.4 11.8 39.7 34.5 44.4 10.3 54.4 45.4 42.2 9.5 8.0 43.0 42.2 37.6 66.0 19.4 65.6 125.2 44.0 17.0 72.3 34.1 53.1 54.8 46.5 64.4 36.8 28.5 34.9 120.3 82.2 22.3 MRPL39 "C21orf92, FLJ20451, L39mt, MGC104174, MGC3400, MRP-L5, MSTP003, PRED22, PRED66, RPML5" ENSG00000154719 "Mitochondrial ribosomal protein L39" Q9NYK5 21 25585656-25607517 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 241.5;Spermatocytes: 103.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018331 Approved Supported Mitochondria NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Mitochondria "HPA018331: AB_1854111" "unprognostic (3.81e-3)" "unprognostic (5.34e-2)" "unprognostic (8.55e-3)" "unprognostic (4.61e-1)" "unprognostic (2.61e-1)" "unprognostic (4.32e-2)" "unprognostic (6.75e-2)" "unprognostic (2.35e-1)" "unprognostic (4.74e-2)" "unprognostic (1.94e-1)" "prognostic unfavorable (5.84e-4)" "unprognostic (7.48e-2)" "unprognostic (7.32e-3)" "unprognostic (9.81e-2)" "unprognostic (1.66e-1)" "unprognostic (2.45e-2)" "unprognostic (6.89e-2)" 23.1 35.6 18.2 19.7 19.6 22.7 26.7 22.1 28.7 16.7 18.4 29.2 25.5 18.0 41.7 26.5 20.4 13.5 51.4 18.3 19.2 40.4 55.3 15.3 34.2 18.7 18.1 17.6 25.2 71.0 13.4 26.2 19.8 20.0 32.1 21.5 21.8 17.8 58.6 20.3 23.1 22.0 19.0 17.6 22.9 54.7 18.2 24.9 20.1 56.7 37.3 22.3 18.8 21.6 89.6 43.0 60.1 38.1 29.7 42.9 92.3 56.1 50.0 77.0 64.7 85.2 49.2 97.9 30.9 35.4 69.8 25.5 128.5 76.4 85.9 49.1 66.3 100.1 43.0 91.4 34.6 102.4 31.7 34.8 66.7 76.3 62.2 42.7 58.2 99.6 112.3 78.4 77.1 56.0 67.5 55.5 95.6 88.9 65.4 77.8 97.0 103.1 80.6 35.7 37.9 36.3 51.6 94.5 76.3 42.3 68.3 57.6 36.4 40.8 61.0 43.9 69.6 54.9 74.6 121.9 61.2 109.1 62.5 41.9 16.9 20.7 37.0 30.3 46.9 62.0 45.0 42.3 31.0 49.1 43.9 39.3 2.8 36.7 21.6 43.2 56.4 18.6 18.2 19.6 22.1 28.7 18.3 19.2 18.7 18.1 19.8 19.0 18.2 21.6 18.3 25.6 10.5 9.8 17.6 20.0 20.3 71.0 7.4 20.4 14.0 23.5 78.2 10.0 36.2 25.8 10.4 46.8 14.1 8.7 31.3 36.0 241.5 20.9 12.7 22.2 7.8 22.3 11.4 33.8 41.7 19.4 7.1 11.8 15.2 11.3 18.9 19.8 30.8 10.1 11.7 11.4 30.5 10.6 15.7 37.0 14.9 11.3 19.6 9.4 17.1 19.0 11.3 9.5 13.2 26.5 9.3 23.3 13.6 13.2 20.4 46.8 41.8 15.0 46.0 18.1 25.4 103.0 29.4 10.7 16.9 36.9 14.9 25.7 20.1 17.3 MRPL46 "C15orf4, LIECG2, P2ECSL" ENSG00000259494 "Mitochondrial ribosomal protein L46" Q9H2W6 15 88459477-88467390 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 119.3;Proximal tubular cells: 133.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050166, HPA076046" Approved Supported "Nucleoplasm,Cell Junctions,Mitochondria" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "Nucleoplasm, Cell Junctions" "HPA050166: AB_2681039, HPA076046: " "unprognostic (1.42e-1)" "unprognostic (6.94e-3)" "unprognostic (1.02e-1)" "unprognostic (1.21e-2)" "unprognostic (3.28e-2)" "unprognostic (5.16e-2)" "unprognostic (6.22e-2)" "unprognostic (1.84e-1)" "unprognostic (1.79e-1)" "unprognostic (4.64e-3)" "unprognostic (7.78e-2)" "unprognostic (5.65e-2)" "prognostic favorable (2.09e-6)" "unprognostic (7.73e-2)" "unprognostic (9.18e-2)" "unprognostic (6.96e-3)" "unprognostic (1.63e-1)" 25.1 51.5 20.3 12.9 21.7 11.3 22.7 23.7 25.4 14.6 22.0 24.2 20.0 17.1 18.2 26.4 17.1 13.0 76.1 20.8 23.6 34.7 70.9 12.7 20.9 23.1 22.1 17.2 16.2 24.6 16.2 19.6 23.6 14.9 23.6 16.8 17.1 15.2 73.3 17.9 19.7 18.4 21.7 19.1 24.8 28.1 22.7 18.9 17.2 84.6 20.3 20.7 16.2 22.6 27.8 87.2 27.2 29.8 38.0 28.6 51.5 38.6 35.5 56.9 50.4 108.6 59.3 64.9 38.6 34.9 51.0 65.9 107.4 47.4 44.8 26.3 86.4 53.6 61.5 114.3 24.6 54.2 40.4 32.7 56.6 42.8 28.7 29.0 50.2 63.2 60.7 26.6 42.7 59.6 44.2 68.4 43.5 50.5 52.9 51.9 37.9 49.2 44.5 88.2 42.1 26.5 36.6 57.7 81.8 44.6 64.8 65.7 31.3 44.0 41.9 23.3 56.4 24.2 55.7 53.0 48.5 58.1 34.2 27.1 45.5 33.7 60.0 60.5 69.6 78.8 63.3 58.7 58.7 69.5 69.5 61.6 7.9 62.9 45.0 50.5 68.0 61.5 20.3 21.7 23.7 25.4 20.8 23.6 23.1 22.1 23.6 21.7 22.7 22.6 18.9 0.0 10.3 5.2 21.0 13.8 22.4 59.8 9.6 21.2 17.3 21.3 70.4 37.1 32.3 36.8 27.1 94.3 10.7 20.4 119.3 35.0 67.1 20.0 16.6 18.4 28.3 17.7 4.2 38.0 42.1 19.2 19.9 19.5 22.2 25.8 17.2 105.0 35.6 15.2 5.9 20.6 44.7 13.4 5.5 16.3 14.3 10.8 7.2 3.7 42.1 25.1 20.6 4.5 6.1 31.7 18.4 18.8 17.3 21.9 32.1 133.6 26.2 28.4 26.3 19.5 25.5 55.3 27.4 27.1 23.3 80.7 18.5 66.9 36.1 29.4 MRPL47 "CGI-204, NCM1" ENSG00000136522 "Mitochondrial ribosomal protein L47" Q9HD33 3 179588285-179604649 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 399.7;Spermatocytes: 301.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037553, HPA047779" Approved Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Mitochondria "HPA037553: AB_10671375, HPA047779: AB_2680154" "unprognostic (6.37e-2)" "prognostic favorable (6.44e-4)" "unprognostic (7.21e-2)" "prognostic unfavorable (3.15e-4)" "unprognostic (1.53e-1)" "unprognostic (8.55e-3)" "unprognostic (1.16e-2)" "unprognostic (1.82e-2)" "unprognostic (1.58e-1)" "unprognostic (8.03e-3)" "unprognostic (1.70e-2)" "unprognostic (1.29e-2)" "unprognostic (5.64e-2)" "unprognostic (3.06e-1)" "unprognostic (1.75e-1)" "unprognostic (1.71e-1)" "unprognostic (8.84e-2)" 27.2 34.8 30.6 24.0 31.7 48.8 27.2 34.2 41.1 19.4 34.2 32.1 23.7 23.0 22.8 31.8 18.9 18.5 54.9 29.4 34.7 44.4 35.5 20.1 30.0 32.0 31.8 16.6 17.4 33.9 24.0 22.2 32.6 20.6 31.8 26.6 21.1 18.9 52.5 21.5 22.6 24.7 33.3 24.3 26.2 53.1 32.6 33.3 21.0 56.9 30.4 32.0 21.7 34.2 128.6 48.6 83.0 76.7 51.5 53.5 95.2 73.2 65.1 112.3 93.2 198.6 51.8 104.7 140.6 62.5 137.2 94.5 103.5 76.9 120.5 121.0 90.9 99.8 46.1 112.5 99.8 182.2 54.2 49.6 65.7 83.4 84.7 53.1 77.2 95.9 59.5 81.4 88.1 98.9 98.4 168.4 144.3 115.4 114.6 102.7 81.1 175.3 120.4 79.6 71.8 83.5 80.7 128.6 151.2 61.9 198.6 136.6 61.6 60.7 87.4 77.1 204.5 102.1 182.4 229.3 70.7 147.4 75.8 38.2 32.4 44.2 31.7 43.8 32.2 35.1 35.1 34.7 48.4 31.8 30.4 31.7 8.5 41.5 54.4 41.9 48.9 35.8 30.6 31.7 34.2 41.1 29.4 34.7 32.0 31.8 32.6 33.3 32.6 34.2 45.3 22.4 21.7 5.5 51.4 74.9 82.0 179.7 38.7 20.2 36.4 33.4 89.7 54.3 78.6 57.0 10.4 100.0 61.2 46.3 258.2 112.3 399.7 72.8 56.0 55.5 54.9 62.9 7.1 115.9 109.6 51.8 36.2 50.0 56.4 34.0 44.3 62.5 99.3 10.1 9.2 52.8 105.8 42.4 55.7 95.4 42.9 53.5 48.0 4.7 80.3 43.4 39.1 7.1 12.4 118.7 53.6 49.2 54.6 72.6 45.2 201.7 85.5 26.0 59.2 57.9 68.2 301.2 54.0 52.2 70.5 104.1 57.8 102.3 71.9 83.8 MRPL53 ENSG00000204822 "Mitochondrial ribosomal protein L53" Q96EL3 2 74471982-74472687 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034612, HPA056185" Uncertain Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA034612: , HPA056185: AB_2683060" "unprognostic (2.22e-2)" "unprognostic (1.94e-2)" "unprognostic (2.81e-2)" "unprognostic (1.81e-1)" "unprognostic (2.04e-1)" "unprognostic (2.88e-2)" "prognostic unfavorable (7.36e-5)" "unprognostic (3.60e-2)" "unprognostic (1.24e-1)" "unprognostic (4.06e-2)" "prognostic favorable (1.37e-4)" "unprognostic (1.26e-1)" "prognostic unfavorable (1.16e-8)" "unprognostic (8.76e-2)" "unprognostic (2.79e-1)" "unprognostic (4.13e-1)" "unprognostic (2.45e-2)" 60.9 82.9 68.8 46.8 72.2 61.8 38.9 77.0 98.9 31.3 79.2 41.5 48.0 28.7 39.1 41.0 50.2 34.0 114.4 67.1 72.3 54.5 65.1 34.2 78.4 72.3 69.3 61.5 118.0 72.1 35.1 34.8 72.7 46.0 20.3 27.1 107.1 36.2 169.7 27.3 45.9 24.4 74.2 54.7 55.0 23.1 70.2 50.3 47.1 89.0 42.3 44.7 27.0 76.5 101.5 271.0 60.0 58.5 77.9 69.7 103.4 79.8 73.7 70.5 60.9 224.7 130.1 87.6 78.8 61.4 97.3 76.3 32.5 105.7 24.5 174.6 188.3 77.7 115.6 133.7 70.7 88.4 85.6 96.7 75.1 90.4 59.0 82.3 75.3 109.0 93.0 156.6 63.8 316.5 118.6 163.3 57.5 166.0 204.5 89.1 196.0 212.9 88.9 115.6 103.5 128.0 74.1 195.6 137.3 40.8 102.3 111.1 83.6 115.9 119.6 101.7 135.2 292.3 260.6 141.1 116.4 94.8 125.8 244.9 293.8 133.8 168.2 277.6 188.5 350.0 215.9 173.1 250.3 367.5 282.0 211.4 185.5 167.6 271.8 360.3 275.3 345.5 68.8 72.2 77.0 98.9 67.1 72.3 72.3 69.3 72.7 74.2 70.2 76.5 5.2 9.6 23.2 4.6 18.0 17.2 6.0 9.7 12.0 2.0 24.0 16.4 1.6 4.3 12.1 11.0 0.0 14.7 10.5 29.5 21.5 32.8 8.9 7.2 4.3 11.2 39.7 18.9 3.4 56.9 17.5 10.9 15.3 4.7 33.6 3.0 16.1 23.8 18.0 1.7 3.5 27.2 6.1 25.9 23.9 2.3 8.7 15.6 26.6 2.8 35.8 4.6 15.5 2.0 7.1 35.8 43.5 4.5 34.8 4.9 41.8 45.3 46.1 4.0 6.6 7.7 11.2 11.2 6.8 16.6 25.1 15.7 14.6 3.3 21.7 6.9 MRPS11 "FLJ22512, FLJ23406, HCC-2" ENSG00000181991 "Mitochondrial ribosomal protein S11" P82912 15 88467453-88480776 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043752, HPA050345" Enhanced Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA043752: AB_2678653, HPA050345: AB_2681100" "unprognostic (2.66e-1)" "prognostic favorable (3.60e-4)" "unprognostic (6.51e-2)" "unprognostic (1.35e-1)" "unprognostic (1.12e-1)" "unprognostic (3.21e-1)" "unprognostic (3.45e-1)" "unprognostic (1.44e-1)" "unprognostic (6.45e-2)" "prognostic favorable (4.75e-4)" "unprognostic (8.31e-2)" "unprognostic (3.37e-1)" "unprognostic (1.83e-1)" "unprognostic (9.44e-2)" "unprognostic (7.26e-2)" "unprognostic (7.85e-2)" "unprognostic (1.74e-1)" 9.4 16.9 12.0 4.0 12.1 2.8 8.6 12.8 18.3 5.3 11.4 9.3 7.9 5.3 3.8 10.9 4.8 4.5 26.1 12.5 12.1 14.0 20.5 5.2 5.6 12.7 12.3 3.5 10.5 3.8 7.6 2.3 12.9 7.4 3.5 2.5 6.0 3.4 24.7 7.2 7.4 4.3 11.7 8.0 9.6 9.0 12.7 5.1 9.6 15.0 4.4 8.4 5.6 12.1 10.5 41.1 6.1 10.4 13.8 6.6 16.1 8.3 14.6 10.7 11.5 28.9 16.0 9.7 17.0 7.1 11.3 14.8 17.9 11.5 5.5 12.8 43.8 13.2 23.1 32.0 16.5 4.5 8.3 13.4 11.1 9.2 9.2 5.8 14.3 12.3 9.6 4.3 18.1 45.1 9.3 19.0 16.3 13.4 43.8 19.0 11.6 23.0 15.5 28.4 19.3 9.6 8.6 21.6 33.6 5.3 19.8 24.7 6.8 15.2 16.8 9.9 12.5 8.5 16.5 11.7 18.3 11.2 16.3 31.1 25.1 19.3 15.1 27.6 17.6 27.5 17.2 17.8 29.5 18.2 18.1 17.6 9.5 30.1 17.8 31.9 35.1 26.0 12.0 12.1 12.8 18.3 12.5 12.1 12.7 12.3 12.9 11.7 12.7 12.1 42.1 6.4 20.4 10.4 30.4 22.8 27.5 69.2 31.9 36.9 38.1 47.2 6.3 35.8 39.6 46.0 47.9 91.0 34.6 85.5 135.0 63.9 30.2 27.1 37.8 34.2 24.7 40.6 14.0 66.8 89.7 32.7 25.0 32.5 33.6 40.4 44.6 92.6 90.5 26.9 15.0 60.3 50.8 33.1 24.5 34.2 33.2 31.0 32.0 8.4 65.0 44.4 72.1 16.6 16.8 67.0 70.7 42.5 36.5 32.2 90.8 145.3 29.7 45.1 19.7 29.7 51.8 90.3 42.0 49.1 28.3 89.6 32.3 96.0 64.6 34.5 MRPS17 "HSPC011, MRP-S17, RPMS17" ENSG00000239789 "Mitochondrial ribosomal protein S17" Q9Y2R5 7 55951877-55956500 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "A-431: 195.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047159 Approved NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 1: Pancreatic cells - Digestion" "HPA047159: AB_2679961" "unprognostic (3.38e-1)" "unprognostic (2.71e-2)" "unprognostic (1.24e-1)" "unprognostic (8.61e-3)" "unprognostic (2.16e-2)" "unprognostic (1.94e-2)" "unprognostic (7.07e-3)" "unprognostic (1.80e-1)" "unprognostic (3.92e-1)" "unprognostic (2.86e-2)" "unprognostic (1.79e-2)" "unprognostic (1.47e-1)" "unprognostic (4.20e-3)" "unprognostic (7.17e-2)" "unprognostic (2.36e-2)" "unprognostic (2.24e-1)" "unprognostic (2.63e-1)" 9.6 13.6 14.8 7.8 15.0 10.2 11.2 14.8 18.3 7.4 11.6 13.0 8.9 9.9 9.2 13.5 10.1 5.1 20.0 15.6 15.1 16.8 22.1 6.9 9.1 14.3 13.9 9.5 13.6 9.7 8.3 6.5 14.8 10.4 9.8 5.6 9.0 10.5 32.9 8.2 9.1 9.3 13.0 10.2 11.6 11.9 15.9 9.1 8.2 32.7 9.3 11.0 7.8 14.6 195.1 25.3 17.4 36.6 17.3 16.9 22.0 20.6 20.3 25.0 28.4 31.0 26.0 49.3 29.6 16.9 57.9 43.3 38.6 39.3 30.1 20.7 30.0 14.7 35.8 32.2 24.9 37.4 14.5 19.4 31.6 25.0 41.2 18.3 26.5 27.8 57.9 19.2 22.6 21.8 29.9 51.4 37.4 47.7 43.2 23.9 16.8 38.9 40.4 23.4 25.7 22.6 23.4 76.1 28.5 29.6 49.9 29.3 17.9 8.3 40.8 60.2 47.8 16.7 34.2 83.2 8.4 18.9 38.2 3.6 8.7 2.7 10.5 10.7 12.7 17.1 14.4 15.2 13.3 14.2 16.1 14.3 2.3 12.5 11.0 13.2 15.5 7.9 14.8 15.0 14.8 18.3 15.6 15.1 14.3 13.9 14.8 13.0 15.9 14.6 9.6 22.4 11.7 2.6 12.3 0.0 21.3 0.0 26.7 6.7 14.3 14.4 0.0 22.8 14.2 5.5 0.0 30.4 8.7 8.2 29.4 48.1 22.6 18.5 9.5 11.3 4.9 30.9 3.5 54.5 26.2 9.9 23.0 10.0 5.1 10.3 18.9 33.7 19.2 18.5 3.9 15.5 0.0 11.6 0.0 5.5 9.3 9.1 0.0 1.0 20.6 10.6 21.6 3.0 4.6 46.0 14.8 10.9 21.3 19.9 24.2 28.9 13.8 7.0 6.6 10.0 11.2 29.2 12.0 31.2 0.0 21.3 10.7 10.8 21.8 11.9 MRPS33 CGI-139 ENSG00000090263 "Mitochondrial ribosomal protein S33" Q9Y291 7 141002610-141015228 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 354.1;Proximal tubular cells: 386.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030425 Uncertain NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "HPA030425: AB_10602030" "unprognostic (9.83e-2)" "unprognostic (2.91e-1)" "unprognostic (2.19e-2)" "unprognostic (1.01e-1)" "unprognostic (1.79e-2)" "unprognostic (4.03e-2)" "unprognostic (5.99e-2)" "unprognostic (3.82e-1)" "unprognostic (3.66e-2)" "unprognostic (4.55e-3)" "unprognostic (6.94e-3)" "unprognostic (4.26e-1)" "unprognostic (9.80e-3)" "unprognostic (1.16e-1)" "unprognostic (9.52e-2)" "unprognostic (1.01e-1)" "unprognostic (3.52e-2)" 37.7 64.4 43.9 27.5 46.9 25.0 58.5 46.4 68.8 30.3 47.7 65.3 50.1 25.5 79.1 46.3 35.1 22.4 114.5 45.3 48.0 72.7 83.7 20.8 41.0 46.6 45.9 35.2 67.6 81.2 49.1 24.4 48.0 36.6 69.8 29.4 50.0 31.2 173.7 35.9 44.5 26.5 46.8 30.9 44.3 45.3 45.4 41.9 51.7 171.5 43.5 36.9 30.2 47.8 79.0 110.5 61.8 65.7 77.1 104.9 67.6 69.5 68.7 65.1 73.2 67.6 104.9 107.7 100.0 67.3 140.9 50.5 69.5 102.6 89.3 96.6 83.1 67.8 20.6 130.8 93.8 98.3 39.2 99.8 103.0 100.8 89.4 73.3 53.9 108.4 113.3 84.0 128.2 124.8 110.1 153.3 129.3 140.0 125.6 28.4 48.5 186.1 114.9 99.8 111.7 88.2 93.7 93.2 145.5 65.3 79.4 90.8 41.8 56.6 38.4 137.5 75.8 128.3 155.7 126.8 125.3 99.8 95.1 13.0 47.6 37.9 48.9 68.7 61.9 85.4 85.5 61.1 79.5 66.8 98.3 83.5 4.9 79.8 60.5 93.8 77.3 61.2 43.9 46.9 46.4 68.8 45.3 48.0 46.6 45.9 48.0 46.8 45.4 47.8 30.3 38.5 43.6 11.1 54.6 42.6 72.1 207.7 51.2 27.1 101.1 104.6 333.5 82.9 96.5 114.0 31.3 145.4 39.5 96.9 354.1 101.0 136.8 124.2 60.1 42.8 89.7 46.3 8.9 136.8 133.0 55.3 50.0 70.6 48.2 71.4 42.5 221.8 114.1 57.2 9.1 148.3 109.9 59.8 38.1 41.0 57.8 45.7 76.5 8.4 97.4 47.8 51.5 9.0 18.0 95.6 80.6 42.5 88.9 67.1 199.0 386.1 122.5 32.9 19.7 41.0 57.1 157.7 50.8 84.4 45.7 116.8 49.6 82.8 202.3 79.0 MS4A4A "CD20L1, MS4A4, MS4A7" ENSG00000110079 "Membrane spanning 4-domains A4A" Q96JQ5 11 60185657-60318080 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 63.1" "Group enriched" "Detected in many" 7 "Hofbauer cells: 376.8;Kupffer cells: 445.0;Macrophages: 264.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "intermediate monocyte: 61.2;myeloid DC: 27.6;non-classical monocyte: 82.9;plasmacytoid DC: 27.7" "Group enriched" "Detected in many" 30 "dendritic cells: 27.7;monocytes: 82.9" "Cell line enhanced" "Detected in some" "HEL: 35.6;HMC-1: 45.8;K-562: 154.9" HPA029323 Approved NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 1: K-562 - Erythropoiesis" "Cluster 4: Macrophages - Innate immune response" "HPA029323: AB_10601866" "unprognostic (7.93e-2)" "unprognostic (2.05e-2)" "unprognostic (1.37e-3)" "unprognostic (1.98e-1)" "unprognostic (4.46e-2)" "unprognostic (2.31e-1)" "unprognostic (9.66e-2)" "unprognostic (1.59e-1)" "unprognostic (4.56e-1)" "unprognostic (6.65e-2)" "unprognostic (8.10e-2)" "unprognostic (2.11e-1)" "unprognostic (5.02e-3)" "unprognostic (3.32e-2)" "unprognostic (4.66e-2)" "unprognostic (4.89e-2)" "unprognostic (4.21e-2)" 42.8 24.7 3.5 16.5 3.6 6.1 12.3 3.7 8.6 14.1 4.4 14.0 5.2 4.9 3.4 8.9 11.6 25.8 8.4 3.5 3.9 4.8 15.4 28.0 31.3 4.2 3.4 4.1 4.0 3.3 3.3 63.1 3.6 3.4 16.1 2.0 7.6 4.9 2.3 2.9 13.5 20.0 2.5 33.3 6.6 3.0 5.5 11.5 3.7 10.4 7.5 28.0 3.3 4.3 0.3 0.1 0.1 0.6 0.0 0.2 0.7 0.6 0.0 0.2 0.4 0.3 0.9 0.8 0.4 0.0 0.4 0.3 0.5 0.1 0.6 1.6 0.0 35.6 0.7 0.6 0.1 1.2 45.8 0.4 0.3 0.2 0.8 0.2 0.0 0.4 154.9 4.2 0.6 0.7 0.6 0.9 0.7 0.3 0.1 0.7 0.0 2.5 0.1 1.5 0.5 0.5 0.3 0.3 0.1 0.7 0.7 8.9 0.8 1.5 0.6 0.4 0.2 6.0 0.7 0.5 0.2 0.8 0.2 0.1 9.9 0.0 0.1 61.2 0.2 1.0 0.1 0.1 27.6 0.3 0.2 0.1 0.9 1.8 82.9 27.7 0.1 6.0 3.5 3.6 3.7 8.6 3.5 3.9 4.2 3.4 3.6 2.5 5.5 4.3 2.3 0.0 7.9 0.0 3.0 1.8 0.1 0.0 0.6 0.0 0.3 2.2 3.4 2.8 2.5 0.0 0.0 1.8 7.5 0.0 0.0 0.0 0.7 0.0 0.0 5.7 0.0 13.0 0.1 0.0 2.0 1.6 0.0 0.0 7.6 0.0 47.5 4.6 376.8 0.0 0.1 0.0 0.0 445.0 24.9 1.0 0.9 264.6 3.6 10.3 8.3 0.4 0.0 0.0 0.2 0.2 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.1 13.1 1.2 1.1 0.1 0.2 0.7 1.8 3.6 1.5 0.1 0.0 0.1 MS4A6A "CD20L3, MS4A6" ENSG00000110077 "Membrane spanning 4-domains A6A" Q9H2W1 11 60172014-60184666 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 580.8;Hofbauer cells: 376.8;Kupffer cells: 1649.6;Langerhans cells: 470.0;Macrophages: 675.9;monocytes: 429.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 8 "basophil: 406.4;classical monocyte: 1095.3;intermediate monocyte: 345.6;myeloid DC: 638.8;plasmacytoid DC: 454.4" "Group enriched" "Detected in all" 74 "dendritic cells: 638.8;granulocytes: 406.4;monocytes: 1095.3" "Cell line enriched" "Detected in some" 8 "THP-1: 47.9" "HPA011391, HPA076623" Approved Approved Vesicles NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA011391: AB_10603876, HPA076623: AB_2686809" "unprognostic (1.17e-1)" "prognostic favorable (6.33e-4)" "unprognostic (2.35e-2)" "unprognostic (1.21e-2)" "unprognostic (1.00e-1)" "unprognostic (8.51e-2)" "unprognostic (2.33e-1)" "unprognostic (3.75e-2)" "unprognostic (3.61e-1)" "unprognostic (1.76e-1)" "unprognostic (1.91e-1)" "unprognostic (3.20e-1)" "unprognostic (4.75e-3)" "unprognostic (1.06e-1)" "unprognostic (4.66e-2)" "unprognostic (3.94e-2)" "unprognostic (2.97e-2)" 72.6 42.3 10.7 57.5 10.9 33.5 40.0 10.8 22.5 28.1 14.7 41.0 27.8 14.3 9.6 25.7 16.8 61.4 22.8 10.0 11.8 11.5 108.6 56.4 109.1 15.8 13.7 12.3 7.8 8.7 9.8 65.2 14.8 12.4 54.9 1.4 16.0 18.3 5.3 7.3 45.1 52.6 12.4 121.5 24.5 7.8 13.6 32.2 10.0 17.7 47.6 59.9 8.6 17.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 1.3 0.2 0.0 0.0 0.0 0.0 0.0 4.1 0.0 5.7 0.0 0.0 0.0 0.0 4.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 47.9 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 4.1 0.0 406.4 1095.3 8.2 1.6 345.6 3.4 9.6 2.2 1.4 638.8 1.5 1.0 1.0 72.8 2.1 24.4 454.4 1.9 752.8 10.7 10.9 10.8 22.5 10.0 11.8 15.8 13.7 14.8 12.4 13.6 17.6 5.3 6.4 22.9 0.0 16.1 9.3 0.6 0.0 1.2 0.3 2.2 8.0 3.3 17.2 2.5 3.7 0.0 2.0 220.6 0.3 0.0 0.0 2.2 0.4 0.2 12.8 0.0 43.9 0.1 0.0 2.7 4.3 2.6 0.2 13.9 0.1 580.8 20.5 376.8 0.0 0.1 0.1 0.0 1649.6 470.0 5.1 1.5 675.9 14.2 40.3 429.2 0.0 11.3 0.5 0.1 0.0 1.2 0.0 2.0 0.2 0.0 0.5 1.5 0.6 46.0 3.0 4.4 0.5 1.1 2.4 8.0 2.1 10.4 0.1 0.2 0.3 MS4A7 "CD20L4, CFFM4, MS4A8" ENSG00000166927 "Membrane spanning 4-domains A7" Q9GZW8 11 60378485-60395951 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 196.6" "Cell type enhanced" "Detected in many" "Hofbauer cells: 311.4;Kupffer cells: 1060.3;Macrophages: 567.5;monocytes: 184.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "intermediate monocyte: 747.4;non-classical monocyte: 1486.0" "Lineage enriched" "Detected in many" 12 "monocytes: 1486.0" "Cell line enriched" "Detected in some" 25 "THP-1: 114.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA017418, CAB026387" Approved NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "CAB026387: , HPA017418: AB_1854137" "unprognostic (1.43e-1)" "unprognostic (2.60e-3)" "unprognostic (3.24e-2)" "unprognostic (9.67e-2)" "unprognostic (2.04e-1)" "unprognostic (1.81e-1)" "unprognostic (1.04e-1)" "unprognostic (9.51e-2)" "unprognostic (3.02e-2)" "unprognostic (4.85e-2)" "unprognostic (5.79e-2)" "unprognostic (1.90e-1)" "unprognostic (1.43e-2)" "unprognostic (4.59e-2)" "unprognostic (3.90e-2)" "unprognostic (1.18e-1)" "unprognostic (1.03e-1)" 46.9 37.6 6.3 50.9 5.0 10.7 30.7 4.5 13.7 18.2 13.9 21.4 17.6 7.6 4.1 12.7 6.6 46.8 9.9 4.2 8.7 8.0 66.5 75.7 23.2 12.8 10.4 6.0 6.0 9.0 4.7 43.9 11.4 4.9 23.3 1.2 6.7 9.0 1.9 2.3 25.1 15.9 7.4 196.6 14.8 4.7 17.1 18.2 7.3 4.1 18.6 41.2 3.9 18.3 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 2.5 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 4.5 0.1 0.0 0.1 1.1 0.1 0.1 0.0 2.8 0.0 0.1 0.1 0.8 0.5 0.0 0.0 114.2 0.0 0.1 0.1 0.1 0.1 0.2 0.2 3.0 0.0 3.1 0.0 8.3 188.0 2.5 0.8 747.4 1.1 22.3 0.6 0.5 120.9 19.7 0.8 0.4 9.3 0.8 1486.0 3.2 0.9 137.8 6.3 5.0 4.5 13.7 4.2 8.7 12.8 10.4 11.4 7.4 17.1 18.3 5.0 12.8 31.4 0.0 30.6 2.7 0.8 0.0 0.6 3.6 14.7 9.9 2.1 0.0 3.7 9.2 0.0 1.0 1.4 0.3 0.0 0.0 2.4 0.1 0.0 12.2 0.0 10.1 0.1 0.2 1.7 3.9 1.5 0.1 13.9 0.1 11.0 4.7 311.4 0.0 0.2 0.0 0.0 1060.3 93.4 1.2 1.2 567.5 1.8 59.0 184.8 0.4 4.1 0.0 0.3 0.1 1.1 0.0 1.8 1.1 0.0 0.7 7.3 0.5 19.7 2.2 1.2 0.0 0.4 0.9 1.8 1.9 5.3 0.3 0.1 1.0 MSH2 "COCA1, HNPCC, HNPCC1" ENSG00000095002 "MutS homolog 2" P43246 2 47403067-47663146 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" DNA-binding "Cancer-related genes, Disease variant, Hereditary nonpolyposis colorectal cancer, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "testis cancer: 46.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009572, HPA066845, CAB070867" Approved Supported Nucleoplasm,Vesicles NA Yes 28000 "Cluster 48: NK-cells - Unknown function" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Vesicles "CAB009572: AB_2144828, CAB070867: , HPA066845: AB_2732752" "unprognostic (2.35e-1)" "unprognostic (1.54e-2)" "unprognostic (2.89e-3)" "prognostic unfavorable (4.44e-4)" "unprognostic (2.23e-1)" "unprognostic (6.31e-3)" "prognostic unfavorable (1.72e-9)" "unprognostic (1.77e-1)" "unprognostic (7.09e-3)" "unprognostic (8.57e-2)" "prognostic unfavorable (4.63e-4)" "unprognostic (5.38e-2)" "unprognostic (3.29e-3)" "unprognostic (1.20e-3)" "unprognostic (5.74e-1)" "unprognostic (8.46e-2)" "unprognostic (1.48e-1)" 8.1 7.5 8.3 12.8 10.5 15.7 15.7 14.6 10.6 9.7 12.2 11.9 7.8 11.7 14.0 9.5 12.4 5.8 10.1 9.6 9.0 8.2 6.7 8.1 23.7 8.6 8.0 8.7 6.5 14.8 6.2 11.6 9.5 8.6 15.0 34.9 8.5 7.7 7.1 11.1 9.3 8.8 8.5 10.8 8.1 16.2 7.9 32.6 15.8 7.2 25.0 7.9 6.4 8.9 114.3 35.3 103.3 57.9 7.3 21.2 64.3 62.9 33.3 80.9 76.9 72.3 50.1 141.2 84.6 23.8 56.6 49.8 78.6 37.4 122.3 68.1 55.8 99.3 42.3 65.6 7.7 97.7 34.9 12.3 11.2 68.1 19.0 19.1 45.2 3.9 165.1 34.0 63.1 44.2 119.6 75.4 195.7 69.3 45.1 151.1 182.2 84.4 35.8 57.3 85.9 91.6 58.4 49.2 48.0 83.6 46.9 38.8 18.7 55.5 70.9 57.1 74.6 20.8 63.4 180.1 33.1 72.5 35.4 3.0 1.3 4.9 8.0 4.4 9.3 6.7 7.7 10.3 2.5 7.9 12.6 13.1 1.0 14.2 3.9 3.4 11.8 6.5 8.3 10.5 14.6 10.6 9.6 9.0 8.6 8.0 9.5 8.5 7.9 8.9 14.7 9.6 11.5 18.6 13.0 8.3 7.9 14.4 8.6 17.4 7.5 7.1 15.6 5.7 12.6 9.2 45.9 19.9 14.2 6.6 3.9 11.5 17.8 21.0 11.3 13.4 3.5 54.1 59.9 8.4 20.7 12.2 7.1 18.8 12.0 28.2 5.0 1.6 11.4 11.8 58.0 12.1 14.2 4.1 4.6 22.8 5.3 5.1 8.8 16.9 5.5 22.6 17.5 35.7 54.7 7.3 5.0 6.4 12.4 2.8 5.4 4.5 23.3 41.1 0.0 9.8 9.0 56.5 50.8 9.3 6.5 5.1 12.8 24.3 13.5 3.8 MSI1 ENSG00000135097 "Musashi RNA binding protein 1" O43347 12 120341330-120369164 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "retina: 104.3" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 54.2;Early spermatids: 55.4;Late spermatids: 58.2;Muller glia cells: 82.4;Rod photoreceptor cells: 109.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 119.7;HAP1: 55.3;NTERA-2: 62.6;SCLC-21H: 88.4;SH-SY5Y: 42.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA074923, HPA075573" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 77: Retina - Visual perception" "Cluster 12: NES - Nervous system development" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm Cytosol "HPA074923: , HPA075573: " "unprognostic (1.21e-1)" "unprognostic (3.46e-3)" "unprognostic (1.85e-1)" "unprognostic (1.09e-1)" "unprognostic (3.89e-1)" "unprognostic (3.18e-2)" "unprognostic (1.20e-1)" "unprognostic (1.46e-1)" "unprognostic (1.90e-2)" "unprognostic (2.75e-2)" "prognostic favorable (5.99e-4)" "unprognostic (3.66e-1)" "unprognostic (1.46e-3)" "unprognostic (7.61e-2)" "unprognostic (7.35e-2)" "unprognostic (2.70e-2)" "unprognostic (1.19e-1)" 0.5 5.1 11.3 0.3 10.6 0.1 0.8 8.8 11.6 3.2 18.2 1.5 6.1 3.5 1.1 0.9 2.6 0.9 3.3 11.6 10.7 1.0 0.6 0.5 0.3 13.0 13.3 1.8 5.0 1.5 13.7 0.9 9.9 4.0 1.0 104.3 0.7 1.7 22.5 0.7 4.1 1.4 11.0 0.3 4.3 16.2 11.9 0.0 0.8 0.1 0.0 0.5 1.1 8.4 0.1 1.4 119.7 30.5 0.0 0.0 15.2 0.1 0.0 0.8 1.3 21.7 0.6 0.1 1.7 0.0 0.7 0.4 55.3 0.0 0.4 0.6 12.6 0.1 0.5 2.6 0.0 0.0 0.4 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.4 0.0 16.2 0.2 0.3 62.6 0.6 0.7 0.3 0.0 0.5 0.0 0.1 88.4 42.9 0.1 1.0 1.0 11.4 18.5 0.1 0.1 0.5 15.9 0.2 0.1 1.6 0.5 0.2 0.3 0.3 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.3 10.6 8.8 11.6 11.6 10.7 13.0 13.3 9.9 11.0 11.9 8.4 0.1 0.0 0.0 23.8 0.0 1.0 1.4 0.0 1.8 18.4 4.8 2.8 3.3 0.0 0.0 0.0 54.2 0.2 0.0 1.1 1.9 1.2 55.4 3.8 2.1 1.3 10.1 0.0 1.1 5.2 0.6 2.0 0.0 3.5 0.0 1.2 0.0 0.0 0.1 3.3 2.5 3.5 0.0 0.0 0.4 58.2 0.3 0.1 0.0 1.9 0.6 82.4 0.0 9.5 0.5 1.2 12.0 0.4 0.0 8.3 1.2 0.0 0.0 109.9 13.1 4.6 3.2 7.6 3.1 0.1 0.0 0.4 0.1 0.1 8.6 0.6 MSL1 "DKFZp686P24239, hMSL1, MSL-1" ENSG00000188895 "MSL complex subunit 1" Q68DK7 17 40121971-40136917 "Predicted intracellular proteins" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "neutrophil: 8.7" "Lineage enriched" "Detected in many" 5 "granulocytes: 8.7" "Cell line enhanced" "Detected in all" "SK-BR-3: 358.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022800, HPA023567" Uncertain Enhanced Nucleoplasm NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 72: Non-specific - Transcription" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA022800: AB_1853057, HPA023567: AB_1853059" "unprognostic (1.94e-1)" "unprognostic (6.28e-2)" "unprognostic (1.82e-1)" "unprognostic (1.45e-1)" "unprognostic (4.71e-2)" "unprognostic (5.39e-2)" "unprognostic (2.33e-2)" "unprognostic (1.60e-1)" "unprognostic (1.06e-2)" "unprognostic (2.24e-1)" "unprognostic (3.46e-1)" "unprognostic (7.48e-3)" "prognostic unfavorable (3.06e-6)" "unprognostic (2.92e-2)" "unprognostic (7.91e-2)" "unprognostic (5.80e-2)" "unprognostic (2.61e-2)" 60.2 52.0 34.3 48.0 33.6 56.7 56.7 26.1 39.6 76.6 16.1 62.7 51.7 75.1 55.9 48.1 77.5 38.6 46.8 32.1 26.5 57.1 43.9 61.5 50.8 24.1 25.7 58.3 59.3 47.8 78.8 48.5 22.2 59.8 46.8 41.1 56.5 51.9 63.6 60.8 61.6 53.7 21.8 88.2 57.1 66.2 27.9 62.3 79.8 51.6 51.6 53.3 62.0 27.7 35.9 42.2 88.3 57.9 78.5 67.6 45.0 61.6 65.3 76.1 68.4 42.4 37.8 78.8 45.6 65.0 48.4 65.2 74.7 40.5 78.2 68.0 59.6 43.6 60.5 50.6 40.9 59.7 81.6 56.9 63.6 56.1 46.5 77.4 71.0 47.2 69.3 62.8 61.4 22.8 95.0 64.8 37.6 39.4 27.2 77.1 48.7 72.1 55.4 38.9 80.9 48.0 57.5 358.8 46.5 80.1 83.5 81.0 58.7 51.0 56.4 37.8 52.3 98.5 58.5 77.7 52.0 43.7 60.7 0.0 1.0 0.8 1.7 0.6 0.8 1.1 0.9 1.3 0.7 0.9 0.9 0.8 8.7 0.7 0.8 1.4 0.6 0.5 34.3 33.6 26.1 39.6 32.1 26.5 24.1 25.7 22.2 21.8 27.9 27.7 44.1 28.9 40.7 42.7 22.7 50.0 37.8 21.7 69.4 55.2 41.6 32.3 29.5 25.8 25.8 11.0 12.5 15.4 43.8 36.4 3.9 17.2 16.1 35.8 53.9 43.3 31.2 22.3 39.8 20.7 15.4 37.4 20.4 48.1 3.8 24.8 36.4 35.9 25.2 52.2 33.4 29.1 8.2 36.4 42.8 28.5 58.4 34.2 32.0 33.7 30.6 31.3 30.9 25.1 32.4 24.7 32.1 39.9 26.8 72.7 35.4 9.0 32.7 28.4 39.5 29.2 40.7 71.8 49.2 57.5 65.8 17.0 29.9 27.5 31.4 58.7 MSR1 "CD204, SCARA1, SR-A, SR-AI, SR-AII, SR-AIII" ENSG00000038945 "Macrophage scavenger receptor 1" P21757 8 16107878-16567490 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Endocytosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "lung: 120.1" "Group enriched" "Detected in many" 5 "Hofbauer cells: 137.3;Kupffer cells: 322.8;Langerhans cells: 86.0;Macrophages: 172.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 16.9" "Lineage enriched" "Detected in many" 5 "monocytes: 16.9" "Group enriched" "Detected in many" 7 "BJ hTERT+: 105.2;REH: 40.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA000272, CAB032491" Enhanced NA NA 67000 "Cluster 7: Monocytes - Unknown function" "Cluster 19: Lung - Lung function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 4: Macrophages - Innate immune response" "CAB032491: AB_672722, HPA000272: AB_1846269" "unprognostic (8.19e-3)" "unprognostic (4.87e-2)" "unprognostic (1.93e-2)" "unprognostic (2.10e-1)" "unprognostic (9.24e-2)" "unprognostic (1.32e-2)" "unprognostic (5.85e-3)" "unprognostic (2.89e-1)" "unprognostic (9.70e-2)" "unprognostic (1.62e-2)" "unprognostic (7.19e-2)" "unprognostic (8.82e-2)" "unprognostic (2.76e-2)" "unprognostic (9.16e-2)" "unprognostic (7.39e-2)" "unprognostic (6.85e-2)" "unprognostic (4.69e-2)" 25.9 18.4 4.2 17.5 5.4 13.0 9.7 5.5 10.6 11.6 13.6 8.5 6.6 8.0 6.3 6.2 5.6 29.8 8.7 3.8 6.5 6.7 24.9 120.1 7.0 15.0 7.5 6.1 11.4 6.3 2.6 27.4 10.8 3.6 10.6 5.9 6.3 6.4 2.3 3.5 9.4 17.9 6.9 16.0 6.2 6.2 16.9 4.4 5.2 1.4 2.9 17.4 1.9 22.9 1.5 2.1 3.0 1.5 1.4 1.3 1.4 0.7 105.2 0.3 0.6 3.7 0.4 3.4 5.1 1.0 0.7 0.7 0.7 1.0 2.0 0.4 4.3 4.6 5.1 4.2 0.9 2.4 2.5 0.7 0.8 0.8 1.5 1.8 0.2 1.9 1.7 2.9 1.9 4.3 1.4 1.4 0.5 1.6 1.3 40.7 2.3 1.0 2.0 5.8 2.8 1.2 1.0 2.8 0.2 5.0 0.4 1.2 2.4 2.8 0.9 10.8 2.8 9.5 8.6 7.4 1.1 1.5 2.2 1.7 3.3 0.6 1.0 16.9 0.4 1.1 0.7 0.7 1.1 1.5 1.3 0.9 3.2 0.4 8.8 0.5 0.7 0.8 4.2 5.4 5.5 10.6 3.8 6.5 15.0 7.5 10.8 6.9 16.9 22.9 2.0 22.4 35.9 0.0 2.7 2.7 0.0 0.0 0.0 1.6 0.5 1.4 2.0 2.8 8.1 3.7 25.0 0.5 0.1 0.0 1.9 0.0 2.9 0.0 0.0 6.3 0.0 2.7 0.3 0.0 1.0 2.1 0.0 0.0 17.7 0.1 4.6 1.7 137.3 0.0 3.0 0.1 0.0 322.8 86.0 3.6 1.8 172.5 0.0 28.1 3.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.4 6.6 0.7 19.7 1.0 0.7 4.2 1.3 0.1 2.0 0.8 2.6 0.2 0.0 0.3 MST1R "CD136, CDw136, PTK8, RON, SEA" ENSG00000164078 "Macrophage stimulating 1 receptor" Q04912 3 49887002-49903873 "CD markers, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 62.3;stomach 1: 42.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 25.6;Distal enterocytes: 53.9;Gastric mucus-secreting cells: 108.6;Intestinal goblet cells: 25.7;Pancreatic endocrine cells: 31.2;Paneth cells: 30.3;Proximal enterocytes: 27.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 39.3;CAPAN-2: 98.8;HaCaT: 56.3;HBEC3-KT: 59.4;hTCEpi: 83.4;RT4: 67.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA007657, HPA008180, CAB008972" Enhanced Approved Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "CAB008972: , HPA007657: AB_1079292, HPA008180: AB_1079291" "unprognostic (3.84e-3)" "unprognostic (3.86e-1)" "unprognostic (1.92e-1)" "unprognostic (7.33e-3)" "unprognostic (3.82e-2)" "unprognostic (2.32e-1)" "unprognostic (8.07e-3)" "unprognostic (1.54e-2)" "unprognostic (4.12e-2)" "unprognostic (2.15e-1)" "unprognostic (1.24e-3)" "unprognostic (2.28e-1)" "unprognostic (8.08e-3)" "unprognostic (2.38e-1)" "unprognostic (2.18e-1)" "unprognostic (8.00e-3)" "prognostic favorable (2.33e-5)" 5.1 0.3 1.1 5.1 1.1 0.2 3.8 1.1 1.7 5.7 1.3 26.5 25.2 1.3 1.2 17.5 1.7 11.4 3.2 1.1 0.9 3.4 1.1 9.5 2.5 0.9 0.8 1.0 5.8 0.1 2.7 0.8 0.9 4.7 20.1 0.2 5.4 1.0 1.3 62.3 23.9 2.0 0.8 1.6 42.6 8.4 0.9 8.8 3.4 0.7 5.6 9.2 11.5 1.0 39.3 14.4 0.1 0.6 0.0 0.0 2.2 0.5 0.1 0.0 0.0 4.1 98.8 1.7 8.8 0.5 0.1 56.3 0.0 59.4 0.0 0.9 1.0 0.1 25.9 0.9 0.9 0.0 1.2 0.3 83.4 0.2 11.7 0.2 0.1 0.2 0.8 0.3 0.0 5.1 0.1 0.1 0.3 33.1 34.6 2.9 0.0 1.1 35.8 67.9 1.0 0.1 11.5 22.6 0.2 0.1 17.7 0.9 0.3 0.0 0.3 0.3 0.1 0.5 0.2 0.2 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 1.1 1.1 1.7 1.1 0.9 0.9 0.8 0.9 0.8 0.9 1.0 1.6 25.6 10.3 0.7 1.0 8.8 2.2 14.2 6.8 0.0 2.8 2.5 1.0 0.0 10.6 0.0 0.0 0.1 0.2 53.9 0.0 6.4 15.4 2.9 0.8 0.6 4.2 0.0 1.1 10.0 0.4 0.8 108.6 5.3 0.0 0.1 0.0 0.0 0.1 0.0 1.1 25.7 2.0 0.0 1.4 10.5 0.3 0.5 0.0 1.0 0.6 0.0 1.0 2.0 0.1 31.2 30.3 0.0 0.5 2.2 27.6 0.1 7.6 0.0 0.0 0.5 0.9 1.3 1.5 3.2 4.7 0.0 0.5 0.0 20.1 6.2 MTA1 ENSG00000182979 "Metastasis associated 1" Q13330 14 105419820-105470729 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004508, HPA005544" Supported Enhanced Nucleoplasm,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 30: Mammary glandular cells - Lactation" Nucleoplasm Cytosol "CAB004508: AB_627969, HPA005544: AB_1079420" "unprognostic (6.79e-3)" "unprognostic (4.22e-2)" "unprognostic (1.06e-1)" "unprognostic (6.36e-2)" "unprognostic (2.91e-2)" "unprognostic (7.74e-2)" "prognostic unfavorable (4.62e-4)" "unprognostic (6.59e-2)" "unprognostic (1.47e-1)" "unprognostic (6.72e-3)" "prognostic favorable (9.48e-5)" "unprognostic (4.57e-3)" "unprognostic (1.39e-2)" "unprognostic (2.88e-2)" "unprognostic (1.48e-1)" "unprognostic (1.75e-1)" "unprognostic (1.18e-1)" 23.1 23.8 24.1 10.8 23.4 15.4 24.6 23.7 31.0 31.7 19.4 31.2 13.1 29.9 11.6 22.6 31.8 6.2 39.2 24.1 20.1 24.7 24.1 19.6 12.1 22.2 21.5 38.6 30.1 9.4 36.9 9.2 20.1 31.8 5.6 8.3 23.6 12.7 25.6 21.1 22.1 9.0 20.0 26.7 22.5 37.6 22.5 16.5 30.4 7.7 9.1 29.2 24.4 22.3 33.6 26.3 47.9 48.2 18.0 30.5 42.3 26.2 19.9 25.4 24.3 34.4 44.1 65.4 26.7 19.3 17.9 45.3 35.1 25.0 17.1 43.2 59.0 34.1 25.2 35.5 39.6 43.2 25.3 34.4 30.9 18.0 41.1 35.5 36.4 48.0 39.3 27.7 13.4 60.4 78.3 85.2 69.1 47.7 55.1 73.1 29.1 21.5 20.6 26.0 76.9 80.1 35.5 40.5 40.8 24.3 36.7 40.7 26.6 20.4 21.6 34.1 27.8 55.9 28.9 41.3 25.6 28.7 36.6 0.1 0.2 0.8 0.3 0.2 0.3 0.3 0.2 0.2 0.2 0.3 0.3 0.4 0.0 0.4 0.1 0.9 0.2 0.2 24.1 23.4 23.7 31.0 24.1 20.1 22.2 21.5 20.1 20.0 22.5 22.3 32.1 3.2 16.0 37.9 20.9 15.6 28.8 14.6 13.1 0.0 64.8 38.6 9.2 27.1 15.2 35.0 0.0 11.6 17.7 17.2 17.6 13.2 32.8 25.0 28.4 20.4 18.6 25.4 17.2 19.6 8.0 21.8 28.1 23.9 5.7 47.6 18.2 15.5 11.0 0.0 16.1 21.6 10.2 18.5 13.5 11.3 36.1 15.7 12.4 21.5 13.8 0.0 20.6 32.6 27.0 16.3 11.5 32.0 17.8 45.4 18.5 8.8 27.0 0.0 19.7 30.5 25.4 21.5 13.3 16.8 19.0 9.3 18.7 27.1 24.9 46.2 MTCH2 SLC25A50 ENSG00000109919 "Mitochondrial carrier 2" Q9Y6C9 11 47617315-47642607 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 569.2;Proximal tubular cells: 508.1;Spermatocytes: 435.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038390 Approved Approved Mitochondria NA NA 14000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 18: U-2197 - ECM organization" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA038390: AB_10669723" "unprognostic (4.94e-2)" "unprognostic (3.29e-1)" "unprognostic (1.93e-2)" "unprognostic (1.43e-1)" "unprognostic (4.27e-1)" "unprognostic (7.63e-3)" "unprognostic (1.80e-1)" "unprognostic (7.03e-2)" "unprognostic (1.51e-1)" "unprognostic (1.53e-2)" "unprognostic (1.08e-1)" "unprognostic (1.14e-1)" "prognostic favorable (9.05e-6)" "unprognostic (1.12e-2)" "unprognostic (8.75e-2)" "unprognostic (2.25e-1)" "unprognostic (1.77e-1)" 28.8 40.3 13.2 14.1 14.1 12.6 25.3 14.3 15.7 20.5 12.7 41.7 38.9 26.8 19.4 50.3 18.9 11.9 41.0 13.8 15.1 57.3 115.3 20.0 14.7 13.3 14.0 13.6 22.6 21.2 18.5 9.9 13.7 18.3 32.7 16.2 29.8 11.9 81.8 28.7 37.6 21.4 12.8 19.6 22.6 69.8 14.7 14.6 21.6 47.5 23.0 23.2 26.1 14.9 47.8 51.2 42.9 57.9 49.7 45.8 31.6 50.5 46.1 66.7 62.6 40.9 47.2 65.4 26.8 62.3 71.7 58.5 77.7 66.4 80.9 33.0 73.4 37.5 69.3 82.5 68.2 79.1 36.1 52.1 51.5 44.3 65.8 38.6 61.1 55.1 70.9 38.0 82.9 69.3 61.1 59.5 46.4 92.4 77.0 56.1 65.4 47.0 78.5 60.6 51.0 35.7 69.1 68.8 37.1 40.3 99.2 36.4 51.2 60.9 52.9 102.4 65.8 40.5 49.3 73.2 50.4 67.7 55.7 13.3 33.8 14.1 20.3 37.6 19.6 25.1 17.7 19.2 44.0 19.5 15.1 17.6 3.2 22.2 31.5 28.9 24.0 34.1 13.2 14.1 14.3 15.7 13.8 15.1 13.3 14.0 13.7 12.8 14.7 14.9 28.4 22.4 35.9 54.9 39.2 47.0 56.0 169.3 44.9 0.0 50.7 41.3 67.8 71.4 84.0 53.3 0.0 82.8 41.2 98.1 181.9 153.3 569.2 48.8 37.5 31.6 79.8 74.6 47.0 109.4 119.1 40.0 46.4 40.1 37.3 29.3 33.2 289.4 164.2 0.0 50.9 97.0 150.5 65.7 40.3 166.5 28.9 67.5 81.8 22.5 103.9 0.0 30.9 58.8 58.6 93.0 69.7 58.3 70.9 84.9 213.3 508.1 79.0 0.0 32.9 30.0 141.3 435.4 104.4 129.8 54.1 127.8 34.5 74.4 165.5 65.2 MTHFS HsT19268 ENSG00000136371 "Methenyltetrahydrofolate synthetase" P49914 15 79833585-79897379 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Ligase "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 253.4" "Cell type enhanced" "Detected in many" "Hepatocytes: 205.5;monocytes: 150.8;Proximal tubular cells: 201.6;Syncytiotrophoblasts: 253.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 134.1" "Group enriched" "Detected in all" 5 "granulocytes: 134.1;monocytes: 49.1" "Low cell line specificity" "Detected in many" "HPA008067, HPA054177" Approved Supported Cytosol NA NA 13000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 62: Liver - Hemostasis" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "HPA008067: AB_1078882, HPA054177: AB_2682405" "unprognostic (4.57e-2)" "unprognostic (9.76e-2)" "unprognostic (6.11e-2)" "unprognostic (1.82e-1)" "prognostic unfavorable (8.52e-4)" "unprognostic (9.13e-3)" "prognostic favorable (1.29e-6)" "unprognostic (1.34e-2)" "unprognostic (1.03e-1)" "unprognostic (6.18e-3)" "unprognostic (2.91e-2)" "unprognostic (2.76e-1)" "prognostic favorable (2.04e-4)" "unprognostic (1.36e-1)" "unprognostic (2.85e-1)" "unprognostic (7.60e-2)" "unprognostic (2.90e-1)" 21.9 19.8 8.0 4.6 8.2 5.0 19.0 9.6 12.7 9.9 6.9 12.0 13.7 9.0 10.3 10.1 9.4 7.0 19.0 8.0 9.2 53.1 253.4 17.8 6.4 8.7 9.3 8.6 32.8 26.3 21.5 8.3 9.1 19.5 6.4 5.9 13.6 5.5 20.2 6.2 14.5 6.2 8.8 14.9 19.5 12.1 8.7 10.6 15.9 11.1 10.8 12.4 9.9 9.1 12.6 35.8 5.0 2.6 15.8 12.0 11.9 8.8 13.0 16.4 10.5 34.5 22.4 15.1 25.1 15.5 15.0 19.5 31.9 10.7 15.4 14.7 28.4 14.8 22.9 39.8 25.3 7.8 0.8 17.5 27.8 8.1 23.0 19.6 7.4 16.0 28.8 12.0 17.4 36.0 10.2 36.1 15.6 51.4 17.0 10.8 17.2 25.8 35.1 34.3 8.9 4.8 25.1 14.2 43.8 20.0 17.3 13.0 3.3 5.7 11.1 3.6 7.1 6.8 20.2 17.8 3.3 25.9 6.2 17.5 25.7 73.5 9.4 35.3 12.4 13.5 13.7 12.9 12.3 11.1 16.5 12.6 134.1 17.8 49.1 13.3 15.7 19.1 8.0 8.2 9.6 12.7 8.0 9.2 8.7 9.3 9.1 8.8 8.7 9.1 11.3 19.2 44.0 0.0 20.7 10.7 9.9 63.0 35.9 0.0 25.5 32.5 0.7 58.6 34.3 22.0 0.0 68.1 10.1 10.0 64.6 55.8 2.2 11.9 7.8 10.5 17.6 36.6 0.0 75.7 37.1 13.5 39.8 11.0 8.8 7.2 21.8 205.5 45.7 0.0 0.0 18.7 24.4 22.1 34.8 3.8 13.7 29.3 21.4 0.0 150.8 0.0 35.0 0.0 0.0 75.3 35.9 15.8 13.3 13.3 101.7 201.6 29.9 0.0 13.1 8.4 10.5 6.7 8.5 21.1 8.1 253.8 22.2 9.2 24.9 7.7 MTIF3 "IF-3mt, IF3(mt)" ENSG00000122033 "Mitochondrial translational initiation factor 3" Q9H2K0 13 27435643-27450591 "Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 610.0;Proximal tubular cells: 475.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039791 Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Nucleoplasm "HPA039791: AB_10795296" "unprognostic (1.82e-1)" "unprognostic (1.44e-2)" "unprognostic (2.59e-1)" "unprognostic (3.26e-3)" "unprognostic (1.49e-2)" "unprognostic (8.01e-2)" "unprognostic (1.14e-1)" "unprognostic (1.10e-1)" "unprognostic (2.49e-1)" "unprognostic (3.77e-1)" "unprognostic (1.64e-2)" "unprognostic (1.62e-1)" "unprognostic (2.40e-1)" "unprognostic (3.24e-2)" "unprognostic (1.13e-1)" "unprognostic (9.27e-2)" "prognostic favorable (8.41e-4)" 61.8 55.0 59.5 29.2 59.8 17.1 51.0 61.0 93.4 36.7 60.4 46.7 42.8 28.4 67.1 39.9 30.4 37.0 133.4 59.0 61.7 63.1 65.5 29.2 44.5 60.9 60.2 37.1 54.4 43.4 50.8 30.9 60.9 45.3 44.6 74.7 82.9 43.9 90.8 39.9 41.8 30.5 58.8 49.6 48.1 61.8 60.6 47.3 36.9 109.8 46.1 36.7 34.0 62.0 29.9 21.9 48.5 23.5 53.2 78.8 22.6 44.0 51.1 33.8 33.8 28.3 37.5 33.3 28.4 50.8 22.8 25.1 27.2 37.1 46.3 34.3 31.2 42.6 19.1 36.7 52.2 43.8 38.8 44.6 65.5 27.7 35.1 75.6 60.0 33.8 24.0 13.6 51.2 54.0 39.7 54.2 24.4 100.1 24.0 22.8 24.3 37.5 69.8 31.3 32.9 20.6 28.4 39.1 50.7 51.8 31.3 62.5 38.1 21.4 12.5 56.1 29.5 10.0 14.9 19.1 21.5 44.3 31.1 85.8 53.0 75.4 30.8 51.2 32.9 49.1 38.9 31.1 55.2 42.8 34.0 35.2 36.5 37.2 48.3 88.2 47.4 41.3 59.5 59.8 61.0 93.4 59.0 61.7 60.9 60.2 60.9 58.8 60.6 62.0 88.5 28.9 47.4 29.0 74.0 34.0 34.0 103.9 43.9 0.0 91.6 95.4 179.1 87.2 76.3 115.8 0.0 102.6 60.4 102.2 326.8 89.6 610.0 93.7 63.4 70.3 64.1 59.7 22.8 104.1 67.0 62.7 47.4 74.5 71.7 50.6 79.9 223.0 102.3 0.0 26.4 112.8 103.7 114.8 50.2 283.4 139.8 67.7 106.7 24.4 106.4 0.0 80.3 30.7 43.7 98.3 108.8 124.8 71.1 43.7 142.8 475.5 83.2 0.0 124.9 48.8 69.2 243.6 87.6 62.8 42.5 56.8 58.5 69.6 96.8 44.8 MTMR2 "CMT4B, KIAA1073" ENSG00000087053 "Myotubularin related protein 2" Q13614 11 95821766-95925315 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" Hydrolase "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 120.1;Oligodendrocytes: 226.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049831 Approved Supported Vesicles NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 15: RT4 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA049831: AB_2680904" "unprognostic (1.71e-2)" "unprognostic (2.55e-3)" "unprognostic (7.81e-3)" "unprognostic (4.16e-1)" "unprognostic (4.18e-3)" "unprognostic (5.36e-2)" "prognostic unfavorable (1.61e-8)" "unprognostic (3.23e-3)" "unprognostic (3.42e-2)" "unprognostic (1.77e-2)" "prognostic unfavorable (3.60e-4)" "unprognostic (1.12e-1)" "unprognostic (2.34e-2)" "unprognostic (1.54e-1)" "unprognostic (1.50e-1)" "unprognostic (1.14e-1)" "unprognostic (8.03e-3)" 14.7 9.3 11.0 11.2 16.8 4.4 11.8 16.3 18.3 12.2 12.2 12.9 7.1 12.3 6.2 14.7 12.4 14.3 13.5 10.8 14.3 16.4 4.3 12.3 9.5 15.1 14.4 11.5 7.8 12.7 6.4 24.5 15.8 16.1 13.9 18.6 20.5 11.4 6.2 8.2 8.3 18.0 13.5 8.6 13.0 31.0 14.1 15.1 9.9 8.9 12.1 15.2 10.4 22.4 24.1 25.3 54.1 39.2 19.2 29.0 47.5 43.3 37.9 42.4 37.8 57.3 47.1 16.2 50.3 45.5 35.9 30.9 47.7 48.2 38.9 30.8 21.3 31.5 55.0 33.0 42.8 59.3 26.7 24.0 31.2 56.6 54.5 41.8 64.4 35.4 44.7 14.2 39.6 17.9 29.0 27.2 46.6 59.0 34.9 23.2 32.2 16.8 43.9 125.0 35.6 40.6 43.6 36.4 19.2 35.1 27.6 26.5 64.4 47.7 45.1 34.4 41.1 13.1 42.4 14.3 20.4 15.6 50.6 9.8 3.9 1.7 12.4 4.7 13.4 5.8 7.9 15.7 7.6 4.9 4.0 11.3 0.9 14.1 7.2 3.7 8.1 7.8 11.0 16.8 16.3 18.3 10.8 14.3 15.1 14.4 15.8 13.5 14.1 22.4 19.6 3.2 8.6 28.7 9.6 10.3 15.0 9.0 8.6 0.0 8.0 6.7 17.3 0.0 11.6 9.2 0.0 9.0 8.8 9.1 9.8 17.8 74.8 18.1 14.1 20.2 16.2 12.8 69.8 16.9 34.3 17.0 9.7 8.7 19.0 49.1 11.0 1.0 12.5 0.0 37.5 9.8 24.4 10.3 8.2 120.1 11.1 8.3 3.6 40.3 6.8 0.0 14.4 63.8 226.6 17.7 4.7 12.0 7.0 15.1 6.0 29.3 17.0 0.0 32.9 7.9 29.0 46.8 19.2 15.4 6.0 9.0 8.8 12.9 10.6 15.6 MTMR4 "KIAA0647, ZFYVE11" ENSG00000108389 "Myotubularin related protein 4" Q9NYA4 17 58489529-58517905 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 65.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 52: Non-specific - Transcription" "unprognostic (3.07e-1)" "unprognostic (6.52e-2)" "unprognostic (4.87e-3)" "unprognostic (1.68e-2)" "unprognostic (1.54e-1)" "unprognostic (6.42e-2)" "unprognostic (4.97e-2)" "unprognostic (3.45e-3)" "unprognostic (6.82e-2)" "unprognostic (2.21e-1)" "prognostic favorable (5.09e-4)" "unprognostic (1.04e-1)" "prognostic unfavorable (1.53e-5)" "unprognostic (1.45e-1)" "unprognostic (2.13e-1)" "unprognostic (1.59e-2)" "unprognostic (2.92e-2)" 11.1 12.0 17.8 13.3 16.1 19.1 13.7 21.2 24.0 10.8 9.4 13.9 21.4 11.9 18.3 11.5 11.8 8.0 10.3 19.1 22.5 17.0 41.7 9.6 17.6 49.5 20.0 15.1 13.1 16.0 13.3 12.2 51.6 12.4 17.2 21.1 10.9 10.2 8.2 14.9 21.7 10.9 12.0 15.8 12.2 18.7 24.6 17.2 16.2 10.3 22.6 11.6 10.3 27.7 21.5 23.0 34.3 33.4 20.8 20.8 26.6 12.7 21.6 32.8 30.2 22.5 13.8 44.6 17.6 13.2 25.8 12.3 37.2 21.9 34.9 46.3 25.8 30.4 18.4 30.1 23.0 32.1 26.6 21.8 17.4 22.5 35.7 21.5 24.0 29.7 26.6 31.4 16.6 32.2 63.6 21.3 8.3 40.7 23.1 40.3 25.6 22.0 15.4 44.7 54.4 52.3 12.5 14.7 17.0 17.6 28.6 22.0 13.0 50.9 32.3 14.7 15.6 25.9 30.8 32.7 81.8 24.0 15.7 2.6 3.0 5.8 2.2 3.8 2.0 4.3 2.7 2.5 3.6 4.4 2.9 3.0 3.6 2.0 4.9 2.1 2.8 2.3 17.8 16.1 21.2 24.0 19.1 22.5 49.5 20.0 51.6 12.0 24.6 27.7 10.4 9.6 7.4 30.3 29.3 7.6 12.3 9.3 21.6 0.0 16.1 14.1 11.4 17.2 9.8 3.7 0.0 12.8 9.5 38.2 0.0 9.7 5.1 8.9 15.1 10.7 17.3 23.1 35.0 6.4 21.4 10.0 12.8 10.2 6.3 21.8 12.1 65.7 13.8 0.0 43.9 20.1 2.0 14.2 26.4 6.4 14.3 10.5 12.4 17.8 29.4 0.0 21.6 24.6 39.7 9.1 21.4 17.3 14.6 17.4 48.6 12.0 4.0 0.0 0.0 10.8 13.9 5.3 4.8 13.8 8.2 49.8 15.0 17.5 18.4 9.3 MTMR9 "C8orf9, DKFZp434K171, LIP-STYX, MTMR8" ENSG00000104643 "Myotubularin related protein 9" Q96QG7 8 11284816-11328146 "Plasma proteins, Predicted intracellular proteins" Endocytosis "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 84.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070944 Approved "Actin filaments,Centrosome" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 5: NTERA-2 - Transcription" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Centrosome "Actin filaments" "HPA070944: AB_2686325" "unprognostic (1.97e-2)" "unprognostic (1.95e-1)" "unprognostic (2.30e-2)" "unprognostic (1.32e-2)" "unprognostic (2.16e-1)" "unprognostic (2.64e-2)" "unprognostic (8.09e-3)" "unprognostic (3.25e-1)" "unprognostic (2.05e-1)" "unprognostic (1.46e-1)" "unprognostic (3.38e-2)" "unprognostic (1.12e-1)" "unprognostic (1.06e-2)" "unprognostic (1.07e-1)" "unprognostic (1.73e-1)" "unprognostic (3.08e-1)" "unprognostic (1.43e-2)" 4.6 3.7 7.8 4.3 7.9 3.4 4.9 7.0 8.1 3.5 3.3 6.5 2.4 4.5 2.9 3.4 3.1 3.2 7.5 8.4 8.7 4.4 3.0 3.5 4.0 7.2 8.4 3.6 2.9 4.2 3.0 4.2 8.0 5.0 3.1 17.5 2.6 3.9 5.7 3.8 3.1 5.8 6.3 3.8 3.0 7.7 7.4 3.5 3.7 8.6 3.9 3.7 3.2 8.1 2.9 4.2 7.1 4.8 8.4 7.1 5.0 8.7 5.6 5.1 4.3 3.7 1.5 6.8 2.1 8.1 5.0 3.7 5.2 5.3 6.7 1.2 3.8 6.8 4.5 3.4 8.9 2.2 5.0 6.9 5.9 6.2 9.1 5.8 7.8 3.8 5.0 3.9 10.5 2.1 3.9 2.6 12.4 6.9 4.0 3.0 9.7 2.0 7.7 5.1 2.2 10.6 4.6 2.7 6.7 10.5 2.7 5.4 11.2 7.9 2.3 4.8 4.8 1.3 1.9 3.3 6.9 5.6 7.9 0.2 0.4 0.3 0.7 0.4 0.5 0.5 0.6 0.5 0.2 1.1 0.7 0.7 0.5 0.5 0.4 1.0 0.4 0.2 7.8 7.9 7.0 8.1 8.4 8.7 7.2 8.4 8.0 6.3 7.4 8.1 17.8 12.8 16.8 26.4 27.7 13.6 11.6 12.9 11.4 0.0 11.7 8.4 25.3 24.3 14.5 14.7 0.0 12.4 27.4 7.4 3.9 11.6 17.7 5.1 15.0 18.9 16.2 10.8 44.8 7.1 12.7 18.3 4.6 8.0 14.0 24.9 26.7 17.3 14.5 0.0 42.1 10.7 12.2 21.0 32.7 8.5 23.3 20.2 16.0 18.7 24.3 0.0 25.7 32.2 48.7 15.0 11.1 19.5 11.7 21.6 13.4 10.9 18.0 0.0 39.5 19.0 17.7 84.9 33.1 10.1 12.9 4.5 20.7 14.6 9.5 9.3 MTTP "ABL, MTP" ENSG00000138823 "Microsomal triglyceride transfer protein" P55157 4 99564081-99623997 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 21 "intestine: 275.2;liver: 266.6" "Group enriched" "Detected in many" 9 "Hepatocytes: 244.2;Proximal enterocytes: 605.4" "Cancer enriched" "Detected in many" 13 "liver cancer: 28.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "AF22: 10.8;Hep G2: 12.2" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA051170, HPA054862" Uncertain Approved "Endoplasmic reticulum,Cytosol" "Intracellular and membrane" NA NA 640000 "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 45: Enterocytes - Digestion" "Endoplasmic reticulum, Cytosol" "HPA051170: , HPA054862: AB_2682628" "unprognostic (1.66e-2)" "unprognostic (1.14e-1)" "unprognostic (5.64e-2)" "unprognostic (5.33e-2)" "unprognostic (3.49e-3)" "unprognostic (7.38e-2)" "unprognostic (1.05e-1)" "unprognostic (2.74e-2)" "unprognostic (1.08e-1)" "unprognostic (3.66e-2)" "unprognostic (1.00e-2)" "unprognostic (1.62e-1)" "unprognostic (1.27e-3)" "unprognostic (2.02e-2)" "unprognostic (3.64e-1)" "unprognostic (1.53e-2)" "unprognostic (1.31e-1)" 0.3 0.1 0.9 0.2 0.9 0.0 0.2 0.8 0.9 0.1 0.3 1.3 243.2 0.1 1.0 0.1 0.6 1.3 0.9 0.8 1.5 12.9 266.6 0.3 0.3 1.1 1.6 2.0 0.0 0.0 0.5 0.0 1.3 0.5 0.3 5.6 0.1 0.2 0.4 0.1 275.2 0.5 1.2 0.0 0.8 9.6 1.2 0.2 0.1 0.3 0.1 0.9 0.0 1.9 0.0 0.2 10.8 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.1 0.3 0.0 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 2.7 0.0 0.2 0.1 12.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.6 0.5 0.1 0.2 0.1 0.1 1.0 0.0 0.0 0.7 0.8 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.9 0.8 0.9 0.8 1.5 1.1 1.6 1.3 1.2 1.2 1.9 0.1 0.0 0.0 4.6 0.9 0.0 0.0 0.0 0.0 0.0 0.3 0.4 2.8 4.3 0.1 1.8 0.0 0.2 0.2 0.2 0.0 0.0 44.2 1.0 0.1 0.1 0.0 2.7 1.6 0.0 0.0 0.8 1.5 0.2 0.0 30.1 3.6 244.2 0.1 0.0 0.7 16.7 2.0 3.5 0.0 12.0 0.9 0.2 0.0 0.0 0.6 0.0 0.0 0.0 2.0 0.2 12.5 0.4 0.1 0.0 605.4 23.5 1.0 0.0 6.6 0.5 0.5 32.1 5.7 0.0 0.0 0.0 0.4 12.0 21.0 0.0 MYBPC3 "CMH4, cMyBP-C, FHC" ENSG00000134571 "Myosin binding protein C3" Q14896 11 47331406-47352702 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Actin-binding, Muscle protein" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 584 "heart muscle: 1725.4" "Cell type enriched" "Detected in some" 42 "Cardiomyocytes: 1876.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 17 "U-937: 6.4" "Region enriched" "Detected in some" 33 "cerebellum: 34.4" "Low region specificity" "Detected in many" "HPA040147, HPA043898" Enhanced NA NA 21000 "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 32: U-937 - Innate immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA040147: AB_2676861, HPA043898: AB_2678720" "unprognostic (1.06e-1)" "unprognostic (1.47e-6)" "unprognostic (2.17e-1)" "unprognostic (6.16e-2)" "unprognostic (3.00e-3)" "unprognostic (1.40e-4)" "unprognostic (7.47e-2)" "unprognostic (2.72e-2)" "unprognostic (2.53e-1)" "unprognostic (1.62e-1)" "unprognostic (9.53e-2)" "unprognostic (4.22e-2)" "unprognostic (1.11e-3)" "unprognostic (2.11e-1)" "unprognostic (1.96e-1)" "unprognostic (4.15e-1)" "unprognostic (3.21e-2)" 0.4 2.9 0.0 0.7 0.0 1.5 0.7 0.2 0.4 0.1 0.0 0.2 0.1 0.0 0.0 0.1 0.2 0.4 1725.4 0.0 0.0 0.3 0.3 2.0 0.5 0.2 0.1 0.1 0.7 0.0 0.1 0.1 0.1 0.4 0.0 0.0 0.6 0.0 0.4 0.2 0.3 0.1 0.0 2.8 2.8 1.4 0.0 0.0 0.3 0.2 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.9 0.0 1.3 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1876.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 28.3 0.0 0.0 14.3 0.0 0.0 0.2 0.0 0.0 43.9 0.0 0.0 0.0 0.4 0.0 0.0 0.4 0.0 0.2 0.8 0.0 0.8 0.0 19.2 0.3 0.7 0.0 0.0 1.8 0.0 0.0 0.0 0.2 0.0 0.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.6 0.1 0.9 0.0 0.0 0.3 0.0 17.4 0.6 0.0 MYEOV OCIM ENSG00000172927 "Myeloma overexpressed" Q96EZ4 11 69294151-69367726 "Predicted membrane proteins" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 5.4;breast: 5.3;esophagus: 9.6;stomach 1: 6.0" "Cell type enriched" "Detected in many" 5 "Pancreatic endocrine cells: 199.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 172.8;A549: 83.5;CAPAN-2: 24.3;U-2 OS: 36.1" HPA012949 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" Nucleoplasm Vesicles "HPA012949: AB_1854241" "unprognostic (1.42e-2)" "unprognostic (8.56e-2)" "unprognostic (7.07e-2)" "unprognostic (3.36e-1)" "unprognostic (5.60e-2)" "unprognostic (7.28e-3)" "unprognostic (7.58e-3)" "prognostic unfavorable (2.00e-4)" "unprognostic (3.49e-1)" "unprognostic (6.33e-2)" "prognostic unfavorable (1.54e-7)" "unprognostic (2.83e-1)" "prognostic unfavorable (1.48e-5)" "unprognostic (2.08e-1)" "unprognostic (1.16e-1)" "unprognostic (3.35e-1)" "unprognostic (3.69e-2)" 5.4 0.1 0.0 0.6 0.0 0.1 5.3 0.0 0.0 1.8 0.0 0.5 0.3 0.0 0.7 9.6 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.1 0.1 0.1 0.0 0.0 1.8 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.6 0.0 0.0 4.1 0.2 0.0 0.0 0.2 6.0 0.0 0.0 0.0 0.1 0.0 1.0 0.1 3.9 0.0 172.8 83.5 0.0 0.0 0.0 0.0 2.5 0.2 0.1 0.0 0.0 0.5 24.3 0.5 6.3 0.0 0.1 2.5 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.4 0.0 0.0 6.4 0.0 0.0 0.1 0.0 0.1 8.5 0.0 2.4 0.2 0.1 3.8 0.1 0.1 0.2 3.4 6.8 0.0 0.1 3.5 0.6 0.2 0.0 0.0 0.0 2.4 0.6 0.0 2.9 0.7 1.6 0.1 36.1 0.0 1.4 0.3 1.7 0.2 0.2 0.5 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 1.0 0.8 0.8 3.8 0.0 0.0 30.7 37.7 0.4 0.0 17.6 3.7 0.0 0.0 0.9 7.8 0.0 12.6 12.7 1.2 0.1 0.5 0.0 0.0 0.0 9.4 0.4 3.4 23.9 1.5 0.0 0.1 0.0 0.2 2.4 0.0 0.0 1.3 2.0 0.0 0.0 6.9 0.3 4.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 199.3 22.3 0.0 3.9 1.4 0.0 0.0 1.5 0.0 0.0 0.1 2.9 0.0 0.4 3.4 1.3 0.1 0.4 0.0 2.7 8.5 MYH9 "DFNA17, EPSTS, FTNS, MHA, NMHC-II-A, NMMHCA" ENSG00000100345 "Myosin heavy chain 9" P35579 22 36281280-36387967 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Cell shape" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Alport syndrome, Cancer-related genes, Cataract, Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "TIME: 1343.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001644, CAB015386, HPA064783" Enhanced Supported "Nuclear bodies,Plasma membrane,Actin filaments,Cytosol" No No 410000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane, Actin filaments" "Nuclear bodies, Cytosol" "CAB015386: AB_784698, HPA001644: AB_1079439, HPA064783: AB_2732721" "unprognostic (1.38e-1)" "unprognostic (9.12e-2)" "unprognostic (4.21e-2)" "unprognostic (6.34e-2)" "unprognostic (1.49e-1)" "unprognostic (3.90e-2)" "unprognostic (9.56e-2)" "unprognostic (8.28e-2)" "unprognostic (5.50e-2)" "unprognostic (6.38e-2)" "unprognostic (1.93e-2)" "unprognostic (1.61e-1)" "unprognostic (7.98e-2)" "unprognostic (9.48e-2)" "unprognostic (1.64e-1)" "unprognostic (1.62e-1)" "unprognostic (2.59e-2)" 295.9 95.5 42.3 181.1 42.1 245.9 231.5 40.6 54.7 181.2 65.5 192.6 107.0 356.4 39.3 153.8 182.2 134.5 161.1 50.8 39.4 140.7 101.6 286.2 161.7 52.7 51.7 121.1 160.3 55.0 52.6 166.5 48.1 131.8 89.8 9.7 177.2 98.4 84.0 160.6 163.5 174.1 48.8 232.5 135.8 38.2 52.1 125.1 141.2 46.3 104.1 168.8 166.8 48.2 612.2 277.0 86.2 74.2 156.8 195.1 437.3 398.4 507.5 554.6 413.2 302.1 170.3 156.9 230.1 666.1 265.0 412.7 125.2 779.4 559.6 356.1 120.9 302.6 294.3 259.9 481.1 346.9 463.8 233.0 234.7 751.9 626.4 540.3 461.8 113.2 67.3 205.8 448.9 161.9 124.4 204.0 51.7 171.1 169.2 233.3 267.3 146.7 314.5 581.5 129.6 53.0 559.7 217.0 251.6 218.5 162.4 177.1 1343.7 1222.6 370.3 237.5 731.5 135.2 114.7 129.0 463.2 172.3 363.1 72.6 25.2 64.7 32.4 19.8 28.4 13.4 23.5 26.4 17.2 11.9 18.3 20.4 41.2 9.0 26.5 8.0 26.3 54.5 42.3 42.1 40.6 54.7 50.8 39.4 52.7 51.7 48.1 48.8 52.1 48.2 303.9 118.6 87.1 12.7 108.4 144.0 182.4 123.1 72.8 2.6 90.5 89.4 62.6 80.1 89.7 92.0 2.1 87.0 151.7 359.8 7.9 309.4 35.8 89.7 121.6 258.7 73.8 51.9 42.5 245.8 193.1 82.9 123.8 194.7 93.1 117.1 132.8 102.8 100.4 82.4 6.7 131.0 59.0 119.6 124.2 37.4 68.0 168.8 85.4 61.8 196.6 11.9 137.0 7.5 33.3 344.6 186.8 211.4 125.9 184.4 159.8 27.5 51.5 5.3 203.8 39.9 275.2 6.9 10.4 133.6 135.1 46.4 213.2 141.3 139.5 134.3 MYLK3 "caMLCK, MLCK" ENSG00000140795 "Myosin light chain kinase 3" Q32MK0 16 46702282-46790407 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "heart muscle: 103.4;skeletal muscle: 46.5;tongue: 72.6" "Group enriched" "Detected in some" 12 "Cardiomyocytes: 169.0;Endometrial ciliated cells: 44.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 12.9;HEL: 40.2;K-562: 6.5;SK-BR-3: 7.9" "Group enriched" "Detected in some" 7 "cerebral cortex: 9.6;hippocampal formation: 5.1" "Region enriched" "Detected in single" 5 "hippocampal formation: 3.5" HPA073447 Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 36: HEL - Hemostasis" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm Vesicles "HPA073447: AB_2732225" "unprognostic (6.01e-4)" "unprognostic (2.19e-1)" "unprognostic (2.64e-1)" "unprognostic (1.77e-2)" "unprognostic (1.84e-1)" "unprognostic (2.94e-3)" "unprognostic (2.60e-1)" "unprognostic (4.73e-2)" "unprognostic (3.33e-2)" "unprognostic (2.41e-2)" "unprognostic (6.58e-3)" "unprognostic (1.83e-1)" "unprognostic (4.16e-2)" "unprognostic (2.57e-2)" "unprognostic (2.52e-1)" "unprognostic (1.08e-2)" "unprognostic (2.97e-1)" 0.0 0.1 1.9 0.1 1.7 0.3 0.1 1.1 2.3 0.4 1.7 0.0 0.1 0.3 0.8 4.3 1.7 0.2 103.4 2.5 2.8 1.1 0.1 0.4 0.2 9.8 12.2 0.3 0.1 0.0 0.4 0.5 8.2 2.2 0.1 0.2 2.1 0.1 46.5 0.1 0.1 0.2 5.9 0.1 0.1 6.0 1.9 0.1 0.1 72.6 0.1 0.0 0.0 3.0 0.0 0.1 0.1 0.1 0.0 0.0 12.9 0.0 0.0 0.0 0.0 0.8 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.2 2.0 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 6.5 0.3 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.4 0.4 0.0 7.9 0.2 3.5 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.5 0.1 0.3 0.0 0.1 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 1.9 1.7 1.1 2.3 2.5 2.8 9.8 12.2 8.2 5.9 1.9 3.0 0.2 0.0 3.3 0.7 0.5 0.0 0.7 0.0 0.0 0.9 1.3 0.0 169.0 0.0 3.7 0.0 2.1 2.0 0.2 0.0 0.0 0.0 8.1 44.8 7.1 1.7 0.0 0.0 0.9 0.2 0.5 6.7 0.0 2.2 1.3 1.6 0.7 0.1 0.4 0.0 0.6 0.0 0.0 0.0 0.0 7.2 0.6 0.8 0.0 0.0 0.2 0.8 0.0 0.0 0.2 0.1 0.0 0.0 0.3 0.8 0.0 0.2 8.7 1.3 0.0 4.9 2.7 1.0 0.7 0.0 0.0 0.3 0.8 0.7 0.0 0.8 MYO10 KIAA0799 ENSG00000145555 "Myosin X" Q9HD67 5 16661907-16936288 "Plasma proteins, Predicted intracellular proteins" Transport "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 189.5;Muller glia cells: 233.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "non-classical monocyte: 2.5" "Lineage enriched" "Detected in single" 5 "monocytes: 2.5" "Cell line enhanced" "Detected in many" "HeLa: 182.1;SK-MEL-30: 205.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015224, HPA024223" Enhanced Supported "Nucleoli rim,Plasma membrane,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 22: Non-specific - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane, Cytosol" "Nucleoli rim" "CAB015224: , HPA024223: AB_1854248" "unprognostic (1.13e-2)" "prognostic unfavorable (4.35e-4)" "unprognostic (7.63e-2)" "unprognostic (1.04e-1)" "unprognostic (4.43e-2)" "unprognostic (2.96e-2)" "unprognostic (4.40e-2)" "unprognostic (8.34e-2)" "unprognostic (2.51e-2)" "unprognostic (3.16e-2)" "unprognostic (8.42e-2)" "unprognostic (1.85e-1)" "prognostic favorable (2.75e-4)" "unprognostic (8.93e-2)" "unprognostic (9.86e-2)" "unprognostic (4.56e-2)" "unprognostic (1.84e-1)" 13.8 3.0 47.4 6.2 46.3 3.2 7.9 24.6 41.1 6.7 55.1 19.3 22.8 6.2 3.5 9.3 4.3 8.4 4.5 39.8 24.8 14.7 7.7 19.0 1.3 32.6 30.9 15.8 32.2 10.7 9.5 31.5 27.6 5.8 19.1 15.1 11.0 5.0 8.2 15.6 19.5 4.9 27.3 13.9 32.0 15.6 46.4 4.9 37.5 4.4 2.0 11.1 7.8 45.7 68.2 108.3 31.3 14.9 24.7 17.0 35.1 117.2 89.2 35.5 27.4 63.1 10.2 1.5 78.9 52.9 42.3 33.4 139.1 73.7 57.1 0.2 16.7 0.1 182.1 13.7 81.5 0.4 1.5 30.9 26.8 78.5 92.1 57.4 110.5 0.2 0.2 4.8 28.7 10.5 0.2 0.4 80.5 56.6 37.2 26.1 10.3 66.9 22.0 49.6 5.2 2.8 27.0 11.4 205.0 53.2 8.1 9.1 137.8 77.6 23.6 0.7 61.1 0.7 0.5 0.5 38.3 11.2 76.2 0.5 0.2 0.2 0.1 0.5 0.1 0.1 0.1 0.1 0.2 0.3 0.2 0.2 0.3 0.1 2.5 0.1 0.1 0.1 47.4 46.3 24.6 41.1 39.8 24.8 32.6 30.9 27.6 27.3 46.4 45.7 53.5 35.3 34.6 158.7 1.4 40.9 31.0 23.0 29.6 11.0 18.6 11.6 3.8 55.8 26.3 31.3 18.8 20.4 0.3 46.4 17.6 110.8 30.2 118.5 20.8 61.3 74.0 0.0 3.9 40.6 63.4 13.7 68.3 116.0 27.8 189.5 77.1 1.7 5.6 82.4 5.4 53.2 20.3 7.1 4.8 9.5 12.8 5.7 67.6 87.1 3.8 233.8 0.0 103.5 23.5 114.7 50.3 19.2 0.4 42.6 28.3 4.2 18.8 9.2 65.7 8.2 31.5 3.8 12.2 30.7 31.8 147.8 2.4 4.1 66.9 38.6 MYO16 "KIAA0865, Myo16b, MYR8, NYAP3, PPP1R107" ENSG00000041515 "Myosin XVI" Q9Y6X6 13 108596152-109208005 "Predicted intracellular proteins" "Actin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.4" "Group enriched" "Detected in some" 8 "Inhibitory neurons: 460.0;Oligodendrocyte precursor cells: 299.6" "Cancer enhanced" "Detected in some" "glioma: 1.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 1.0;SH-SY5Y: 4.5;U-2197: 2.7" "Region enhanced" "Detected in all" "olfactory bulb: 72.6" "Low region specificity" "Detected in all" "HPA040110, HPA058769, HPA071948" Uncertain Approved Vesicles NA NA "Cluster 65: Brain - Ion transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA040110: AB_10796339, HPA058769: AB_2683814, HPA071948: AB_2686475" "unprognostic (7.55e-3)" "unprognostic (7.74e-3)" "unprognostic (4.52e-4)" "unprognostic (5.12e-3)" "unprognostic (1.38e-1)" "unprognostic (5.81e-2)" "unprognostic (1.20e-2)" "unprognostic (2.16e-1)" "unprognostic (2.53e-1)" "unprognostic (6.50e-2)" "unprognostic (9.01e-3)" "unprognostic (5.29e-2)" "unprognostic (4.68e-4)" "unprognostic (4.26e-2)" "unprognostic (3.21e-2)" "unprognostic (7.06e-2)" "unprognostic (2.34e-2)" 1.4 0.7 2.5 0.2 4.9 0.0 0.2 1.2 3.7 0.2 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.9 5.4 1.8 0.0 1.9 0.2 0.2 0.6 1.5 0.0 0.1 0.0 1.7 0.1 2.3 0.2 0.1 0.4 0.1 0.7 0.0 0.1 0.0 0.4 2.6 0.0 0.0 1.1 2.6 0.0 0.0 0.2 0.3 0.0 0.2 0.9 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.6 0.0 0.7 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 2.7 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 4.9 1.2 3.7 5.4 1.8 0.6 1.5 2.3 2.6 2.6 0.9 1.0 0.0 0.6 19.6 0.0 0.3 0.0 0.4 0.0 4.2 0.1 0.3 3.7 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.5 11.3 0.5 1.1 0.1 0.0 3.4 44.6 0.0 0.1 0.8 0.0 0.3 1.3 0.1 0.0 5.9 0.1 0.0 460.0 0.0 0.0 0.0 0.3 11.4 0.9 0.1 1.8 8.4 0.0 2.8 0.0 299.6 4.7 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.4 0.0 0.1 0.1 5.0 7.7 0.0 0.0 0.3 0.3 1.6 0.0 0.0 MYO1B myr1 ENSG00000128641 "Myosin IB" O43795 2 191245185-191425389 "Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 255.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 330.2;Hepatocytes: 414.2;Sertoli cells: 203.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-HME1: 360.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013607, HPA060144" Approved Enhanced "Plasma membrane" NA NA "Cluster 37: B-cells - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 2: Hepatocytes - Metabolism" "Plasma membrane" "HPA013607: AB_1854251, HPA060144: AB_2684211" "unprognostic (4.11e-3)" "unprognostic (7.36e-3)" "unprognostic (1.21e-1)" "unprognostic (4.83e-3)" "unprognostic (2.78e-1)" "unprognostic (1.59e-3)" "unprognostic (1.09e-2)" "unprognostic (1.15e-2)" "unprognostic (3.25e-3)" "unprognostic (5.85e-2)" "unprognostic (4.55e-1)" "unprognostic (9.31e-2)" "prognostic unfavorable (2.36e-5)" "unprognostic (2.22e-2)" "unprognostic (1.79e-1)" "unprognostic (1.47e-1)" "unprognostic (6.55e-2)" 42.9 7.3 9.2 15.4 7.8 0.6 27.4 3.5 11.4 13.3 5.8 23.7 13.2 16.2 16.6 15.9 9.2 26.7 19.1 7.1 5.3 25.6 255.5 74.9 11.3 4.2 8.9 14.0 49.3 34.6 5.8 48.4 6.0 15.1 22.0 21.5 12.8 17.7 9.2 15.3 13.4 20.1 3.9 8.2 12.2 9.6 13.2 17.4 19.3 13.6 10.5 25.4 14.3 6.7 102.5 51.7 82.6 24.9 22.4 95.0 74.6 190.8 93.9 129.0 127.4 63.9 8.9 0.1 31.0 220.5 52.1 221.0 27.4 164.3 161.1 0.3 23.9 0.2 22.6 82.3 52.1 2.2 0.6 38.6 111.1 135.0 360.0 47.6 23.8 42.4 0.2 0.4 120.7 43.5 39.7 12.4 53.9 6.7 81.2 50.5 52.6 7.7 51.0 42.8 41.8 109.0 64.5 11.1 57.9 70.2 10.1 3.1 29.1 122.7 61.5 75.0 22.7 0.9 0.5 1.1 74.4 0.4 69.7 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 9.2 7.8 3.5 11.4 7.1 5.3 4.2 8.9 6.0 3.9 13.2 6.7 95.8 330.2 112.5 1.6 3.6 76.7 58.2 78.7 31.9 1.4 29.0 22.9 7.9 45.8 84.3 69.9 0.0 5.2 0.8 30.4 0.0 120.4 2.9 13.0 20.2 60.5 58.5 10.7 22.3 44.6 26.5 40.3 18.3 18.1 3.8 129.1 5.0 414.2 4.2 0.0 38.0 24.6 34.6 10.5 10.0 3.8 5.0 2.3 26.6 70.3 1.0 72.2 0.0 1.0 0.8 38.1 54.1 9.1 0.4 112.2 4.5 1.2 48.2 2.7 203.8 32.6 160.1 2.4 21.0 13.9 28.1 3.4 3.3 44.9 38.0 47.1 MYO1F ENSG00000142347 "Myosin IF" O00160 19 8520778-8577577 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 96.0;lung: 24.4;lymphoid tissue: 78.1" "Cell type enhanced" "Detected in many" "dendritic cells: 110.2;Kupffer cells: 235.4;Macrophages: 122.7;monocytes: 195.5;NK-cells: 616.9;T-cells: 100.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 263.2" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HDLM-2: 52.4;HL-60: 52.3;HMC-1: 87.9;NB-4: 210.2;THP-1: 154.3;U-937: 84.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA055242, HPA056036" Enhanced Enhanced Cytosol NA NA 46000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "HPA055242: AB_2682754, HPA056036: " "unprognostic (4.86e-2)" "unprognostic (5.86e-3)" "unprognostic (1.39e-2)" "unprognostic (1.04e-3)" "unprognostic (1.76e-2)" "unprognostic (2.12e-3)" "unprognostic (2.28e-1)" "unprognostic (2.13e-1)" "unprognostic (2.10e-2)" "unprognostic (2.33e-1)" "unprognostic (7.47e-3)" "unprognostic (2.86e-1)" "prognostic unfavorable (3.27e-4)" "unprognostic (3.23e-1)" "unprognostic (2.64e-2)" "unprognostic (1.57e-1)" "unprognostic (9.35e-2)" 9.6 4.5 5.1 38.9 5.2 96.0 3.5 5.7 7.2 2.7 6.3 5.0 7.4 2.0 0.7 3.3 6.5 10.5 4.6 4.7 5.9 3.8 7.8 24.4 20.7 9.2 7.6 1.2 2.4 1.2 2.2 7.1 8.7 3.7 3.4 0.2 3.7 1.8 1.5 2.7 12.2 6.4 7.5 78.1 6.5 1.4 8.6 5.4 3.0 4.2 8.5 10.2 2.8 10.1 0.1 0.2 0.0 0.2 0.2 0.3 0.2 0.0 0.1 0.0 0.0 0.1 0.1 0.2 6.1 0.4 0.0 0.4 0.0 0.0 0.0 52.4 0.2 38.1 0.0 0.0 0.1 52.3 87.9 0.6 0.1 0.0 0.0 0.1 0.0 0.1 0.5 23.8 0.1 0.3 0.1 210.2 0.0 0.1 0.3 1.0 0.0 5.6 0.1 0.0 0.1 0.3 0.0 0.1 0.3 0.1 0.8 154.3 12.3 0.1 0.2 0.2 0.1 0.1 1.9 0.3 0.3 84.3 0.0 64.5 107.6 105.7 56.6 78.7 44.5 5.9 22.3 39.7 62.8 2.8 1.6 17.0 263.2 32.3 98.8 8.1 34.0 101.3 5.1 5.2 5.7 7.2 4.7 5.9 9.2 7.6 8.7 7.5 8.6 10.1 1.9 3.2 12.3 2.0 26.5 3.3 2.4 0.8 1.2 0.7 3.1 4.3 2.6 5.7 2.9 1.8 2.1 5.0 110.2 2.0 1.9 1.7 6.0 0.6 2.9 4.1 1.2 14.3 2.3 0.9 8.2 2.7 3.6 1.2 31.6 2.2 10.8 6.7 75.8 6.7 1.5 2.1 0.0 235.4 49.3 6.8 2.5 122.7 7.2 64.6 195.5 1.5 616.9 1.5 3.4 1.3 3.2 1.2 30.0 1.8 3.0 2.9 0.2 0.8 0.0 3.4 2.2 6.0 3.4 3.6 5.4 5.1 100.1 3.9 2.7 1.9 MYO5B KIAA1119 ENSG00000167306 "Myosin VB" Q9ULV0 18 49822789-50195147 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 62.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 147.3;Inhibitory neurons: 90.5;Pancreatic endocrine cells: 106.6;Proximal enterocytes: 177.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 65.5;HaCaT: 100.3;RH-30: 152.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA040593, HPA040902, HPA069773" Enhanced Approved "Plasma membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 9: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "HPA040593: AB_10795525, HPA040902: AB_10796230, HPA069773: AB_2686194" "unprognostic (2.51e-1)" "unprognostic (2.15e-2)" "unprognostic (2.12e-2)" "unprognostic (6.17e-3)" "unprognostic (2.14e-1)" "unprognostic (8.84e-3)" "unprognostic (1.32e-1)" "unprognostic (2.59e-1)" "unprognostic (4.13e-2)" "unprognostic (3.46e-1)" "prognostic unfavorable (2.26e-5)" "unprognostic (4.48e-2)" "prognostic favorable (1.45e-11)" "unprognostic (2.17e-3)" "unprognostic (1.50e-1)" "unprognostic (6.56e-2)" "unprognostic (3.28e-1)" 3.2 1.7 1.0 7.9 3.3 0.1 13.7 0.5 3.6 17.7 15.9 45.3 60.2 2.6 18.5 37.4 12.2 11.3 2.7 4.4 10.4 19.7 18.7 11.9 2.6 0.5 3.4 0.5 16.6 23.0 13.4 3.8 1.6 10.1 43.6 40.9 25.4 7.1 0.4 27.4 62.0 3.1 0.4 1.7 33.3 11.4 1.9 3.1 29.4 0.2 13.0 14.2 21.6 1.4 65.5 17.3 0.3 0.3 0.0 0.0 34.0 0.3 2.6 1.4 0.1 45.8 27.2 0.1 15.6 0.1 5.0 100.3 22.6 27.3 1.3 0.2 6.9 0.2 7.5 32.8 0.0 0.2 0.2 0.0 23.6 0.6 16.2 5.1 2.3 0.3 0.5 24.7 2.7 25.3 0.0 0.2 4.6 37.8 7.0 0.0 152.5 11.0 56.8 13.2 33.7 0.7 24.4 28.3 0.0 8.6 16.8 0.2 1.5 0.0 34.0 0.4 6.8 16.7 11.2 0.1 1.4 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.0 3.3 0.5 3.6 4.4 10.4 0.5 3.4 1.6 0.4 1.9 1.4 0.1 54.5 15.8 2.6 1.6 0.4 9.0 7.9 2.2 7.7 14.3 7.7 3.5 15.7 21.5 7.3 10.4 4.4 0.3 147.3 5.9 49.0 22.4 38.5 3.1 1.1 6.7 5.3 4.4 47.3 1.1 3.7 48.4 29.1 0.0 27.1 0.0 18.4 0.9 0.0 90.5 35.4 2.0 1.3 0.8 4.5 0.9 1.0 3.6 3.7 2.0 31.9 0.0 2.0 9.0 106.6 70.7 0.7 1.4 60.1 177.6 18.9 38.1 30.2 0.0 0.9 2.3 9.5 6.7 8.3 6.5 4.7 0.7 0.1 46.7 56.2 MYO6 "DFNA22, DFNB37, KIAA0389" ENSG00000196586 "Myosin VI" Q9UM54 6 75749192-75919537 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Endocytosis, Hearing, Protein transport, Transport" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Cardiomyopathy, Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 409.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 5.5;MAIT T-cell: 3.0;memory CD4 T-cell: 1.8;memory CD8 T-cell: 3.1;naive CD8 T-cell: 3.0;NK-cell: 2.9" "Group enriched" "Detected in many" 7 "NK-cells: 2.9;T-cells: 5.5" "Cell line enhanced" "Detected in many" "RT4: 103.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010762, HPA035482, HPA035483" Enhanced Supported Nucleoplasm NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 15: RT4 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "CAB010762: AB_477166, HPA035482: , HPA035483: AB_2674647" "unprognostic (6.29e-2)" "unprognostic (6.34e-2)" "unprognostic (3.63e-3)" "unprognostic (1.30e-1)" "unprognostic (8.98e-2)" "unprognostic (2.73e-2)" "unprognostic (3.41e-3)" "unprognostic (1.23e-2)" "unprognostic (1.23e-2)" "unprognostic (2.66e-2)" "unprognostic (7.78e-2)" "unprognostic (2.78e-2)" "prognostic favorable (1.27e-12)" "unprognostic (1.57e-1)" "unprognostic (1.72e-1)" "unprognostic (1.41e-1)" "unprognostic (2.49e-2)" 9.9 9.5 18.6 7.1 29.3 0.3 28.3 22.6 32.0 18.5 32.6 22.1 33.0 7.6 22.9 32.0 11.5 27.0 5.3 19.6 19.5 51.4 15.2 23.2 4.7 23.7 24.4 4.7 21.6 40.4 14.5 7.6 24.3 17.2 19.2 49.0 25.9 19.9 3.4 16.8 33.9 5.7 16.0 7.6 27.6 14.6 23.9 5.1 15.9 3.1 12.8 24.0 15.8 34.6 52.2 13.0 12.3 8.9 29.7 23.7 42.6 20.7 23.6 12.3 18.3 22.2 44.2 0.1 16.1 25.7 14.0 40.0 15.3 29.2 18.6 17.0 30.3 17.4 5.6 14.1 25.0 0.0 22.2 17.5 21.6 19.3 14.5 24.0 43.3 7.9 22.4 7.2 15.4 48.3 0.2 0.8 7.7 44.1 3.8 0.7 29.1 1.6 51.1 103.6 26.8 14.8 5.6 46.6 6.8 28.3 16.5 35.8 59.4 13.7 9.3 0.6 20.0 13.2 16.1 0.3 10.9 0.2 5.3 0.2 0.1 0.1 5.5 0.0 3.0 0.2 1.8 3.1 0.0 0.1 0.4 3.0 0.6 2.9 0.1 0.1 0.2 0.8 18.6 29.3 22.6 32.0 19.6 19.5 23.7 24.4 24.3 16.0 23.9 34.6 74.8 141.1 207.0 286.3 4.7 30.1 87.5 49.2 18.2 83.6 99.6 35.9 8.1 38.6 91.3 150.8 120.9 32.0 14.7 112.2 54.8 128.9 7.0 86.9 26.9 57.2 85.0 0.0 147.8 120.3 23.8 30.5 91.7 169.2 26.0 81.0 37.9 33.8 6.3 95.9 167.2 76.4 116.0 2.9 6.1 9.6 30.1 6.7 30.2 105.9 2.7 307.3 12.3 179.4 409.1 197.0 99.7 43.2 11.4 165.9 105.7 97.6 109.5 188.4 13.1 26.5 32.7 14.4 32.1 28.3 34.1 78.4 13.4 191.8 77.5 199.7 MYOZ3 "CS-3, CS3, FATZ-3, FRP3" ENSG00000164591 "Myozenin 3" Q8TDC0 5 150660882-150679368 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 27 "skeletal muscle: 234.2;tongue: 198.4" "Cell type enriched" "Detected in some" 6 "Peritubular cells: 44.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 5.3;NTERA-2: 9.2;REH: 14.8;SuSa: 2.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA039166 Enhanced NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 5: NTERA-2 - Transcription" "Cluster 37: Myocytes - Muscle contraction" "HPA039166: AB_10671871" "unprognostic (2.74e-1)" "unprognostic (2.46e-3)" "unprognostic (9.57e-3)" "unprognostic (1.41e-2)" "unprognostic (1.26e-1)" "unprognostic (3.46e-2)" "unprognostic (2.59e-2)" "unprognostic (8.77e-2)" "unprognostic (9.19e-4)" "unprognostic (6.99e-2)" "unprognostic (5.19e-2)" "unprognostic (7.21e-3)" "unprognostic (7.31e-9)" "unprognostic (2.19e-2)" "unprognostic (2.79e-1)" "unprognostic (8.46e-2)" "unprognostic (4.20e-2)" 0.4 0.5 1.9 0.1 1.5 1.1 0.6 1.3 0.8 1.7 0.1 0.3 0.3 1.5 1.4 5.4 0.8 1.4 5.3 1.4 2.6 0.6 0.1 0.8 0.1 8.0 2.6 0.9 0.2 0.0 1.3 0.1 3.0 4.2 0.2 0.2 3.3 1.0 234.2 0.2 0.7 0.8 5.6 0.2 0.5 3.8 2.7 0.4 0.7 198.4 0.0 0.7 0.5 2.8 0.0 0.0 2.3 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.4 0.0 0.1 0.0 0.1 0.0 0.0 0.0 5.3 0.0 0.2 0.0 0.0 1.2 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.1 0.5 0.7 0.0 0.0 0.1 0.0 0.7 1.4 9.2 0.0 0.0 14.8 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 2.6 0.0 0.3 0.2 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.9 1.5 1.3 0.8 1.4 2.6 8.0 2.6 3.0 5.6 2.7 2.8 3.5 0.0 0.0 1.0 0.1 0.4 0.4 0.5 0.6 1.1 1.7 1.5 2.9 0.0 0.1 0.0 0.0 0.6 0.9 0.3 0.0 0.0 0.3 0.5 0.7 2.5 0.0 0.0 0.9 0.2 0.3 1.8 0.0 1.4 0.0 4.3 2.9 0.0 0.2 0.0 3.0 0.3 2.0 0.3 1.1 1.2 3.1 0.7 0.0 1.0 0.1 0.5 1.0 0.0 0.2 0.0 0.1 44.4 0.0 0.4 0.5 0.0 0.0 0.0 0.0 7.0 0.8 0.4 1.5 0.0 0.4 0.7 0.5 0.4 0.5 0.1 MYT1L "KIAA1106, NZF1, ZC2H2C2, ZC2HC4B" ENSG00000186487 "Myelin transcription factor 1 like" Q9UL68 2 1789113-2331664 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Autism spectrum disorder, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 45.8;pituitary gland: 14.8" "Group enriched" "Detected in many" 4 "Excitatory neurons: 582.4;Inhibitory neurons: 635.5;Oligodendrocyte precursor cells: 265.4" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebral cortex: 45.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "SCLC-21H: 18.6;SH-SY5Y: 7.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060245 Approved Vesicles NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA060245: AB_2732643" "unprognostic (9.90e-3)" "unprognostic (3.74e-1)" "unprognostic (1.30e-1)" "unprognostic (9.61e-3)" "unprognostic (7.17e-2)" "unprognostic (3.73e-2)" "unprognostic (2.44e-1)" "unprognostic (2.36e-2)" "unprognostic (3.21e-2)" "unprognostic (1.93e-2)" "unprognostic (2.46e-1)" "unprognostic (7.96e-2)" "unprognostic (1.21e-2)" "unprognostic (1.04e-2)" 0.0 1.4 7.8 0.2 14.1 0.1 0.0 4.2 45.8 0.0 0.0 0.3 0.1 0.1 0.0 0.1 0.0 0.0 0.0 17.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.5 0.0 14.8 0.1 0.0 0.1 0.1 5.4 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.2 5.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 15.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.1 0.0 0.0 18.6 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.4 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.1 0.0 0.1 0.0 0.1 7.8 14.1 4.2 45.8 17.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 0.1 6.4 6.1 16.6 0.0 1.8 0.5 0.0 0.0 46.7 0.5 0.4 4.5 0.0 3.1 1.8 2.1 0.1 0.2 0.1 0.0 0.0 5.0 0.4 0.1 1.3 0.0 0.0 582.4 0.0 0.2 1.3 0.0 0.2 6.3 0.1 0.7 0.4 0.1 117.8 635.5 0.0 0.0 0.6 0.8 4.7 0.0 0.8 0.0 18.7 0.0 1.5 0.0 265.4 11.1 0.1 0.0 1.5 0.1 0.4 0.0 0.2 1.5 7.4 6.6 1.5 0.4 50.0 31.4 0.0 1.0 0.3 0.9 0.1 0.0 0.6 NAA11 "ARD1B, ARD2, hARD2" ENSG00000156269 "N-alpha-acetyltransferase 11, NatA catalytic subunit" Q9BSU3 4 79225694-79326061 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 2.6;placenta: 4.2;testis: 6.2" "Group enriched" "Detected in some" 12 "Cytotrophoblasts: 19.4;Early spermatids: 30.6;Extravillous trophoblasts: 16.4;Late spermatids: 23.9;Spermatocytes: 25.1;Spermatogonia: 15.9;Syncytiotrophoblasts: 13.3" "Cancer enriched" "Detected in some" 4 "testis cancer: 2.1" "Region enriched" "Detected in single" 5 "cerebellum: 2.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "GAMG: 19.3;K-562: 12.3;U-266/70: 32.9;U-266/84: 11.3" "Not detected" "Not detected" HPA035922 Approved Supported "Nucleoplasm,Golgi apparatus,Centrosome,Cytosol" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "Golgi apparatus, Centrosome, Cytosol" "HPA035922: AB_10673490" "unprognostic (7.37e-2)" "unprognostic (7.58e-2)" "unprognostic (1.36e-1)" "unprognostic (1.20e-1)" "unprognostic (4.67e-1)" 0.0 0.0 0.2 0.0 0.2 0.0 0.0 2.6 0.1 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.5 0.4 0.1 0.0 0.0 0.0 4.2 0.3 0.1 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 6.2 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.1 0.0 19.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 12.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 3.3 0.0 0.3 0.3 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.2 0.0 32.9 11.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 2.6 0.1 0.1 0.2 0.5 0.4 0.3 0.3 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 19.4 0.0 0.0 0.0 0.0 30.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 16.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 23.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.1 15.9 0.0 0.0 13.3 0.0 0.0 0.0 0.0 NAA60 "FLJ14154, NAT15" ENSG00000122390 "N-alpha-acetyltransferase 60, NatF catalytic subunit" Q9H7X0 16 3443649-3486953 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Chromosome partition" "Acyltransferase, Chromatin regulator, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040916 Approved Uncertain "Actin filaments,Cytosol" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 45: Enterocytes - Digestion" "Actin filaments, Cytosol" "HPA040916: AB_10794428" "unprognostic (8.59e-2)" "unprognostic (2.16e-3)" "unprognostic (3.39e-1)" "prognostic favorable (3.14e-4)" "unprognostic (1.81e-1)" "unprognostic (5.90e-2)" "unprognostic (2.88e-2)" "unprognostic (1.53e-2)" "unprognostic (5.23e-2)" "unprognostic (5.12e-2)" "prognostic favorable (4.30e-4)" "unprognostic (9.54e-2)" "unprognostic (1.64e-1)" "unprognostic (1.60e-2)" "unprognostic (8.96e-2)" "unprognostic (3.59e-1)" "unprognostic (6.74e-3)" 25.5 45.4 31.5 16.9 30.0 20.1 25.1 37.5 35.9 28.4 22.7 40.4 40.5 31.6 18.7 31.0 28.2 20.3 48.9 31.9 27.5 52.4 67.5 32.0 20.2 30.8 30.5 26.8 47.9 49.1 41.6 19.5 29.3 35.2 22.6 16.3 26.0 23.9 42.9 24.2 39.3 19.1 28.8 42.9 58.9 32.7 31.2 19.5 32.0 21.2 16.7 28.4 23.2 30.3 16.8 61.9 40.1 44.1 26.5 19.4 39.1 26.9 25.0 29.3 26.6 43.9 30.5 31.7 30.0 29.6 21.0 37.4 40.1 31.2 29.4 49.7 27.8 35.4 25.7 53.0 32.9 53.1 45.6 24.4 27.9 20.4 38.9 29.2 45.1 29.4 44.8 41.4 19.4 73.6 33.4 36.3 50.1 35.8 18.1 42.3 30.8 47.5 27.7 29.7 21.6 42.5 45.8 48.3 24.6 38.5 40.2 34.7 30.8 36.0 27.7 12.8 26.7 35.2 33.6 30.5 12.1 29.0 29.2 33.3 18.6 53.8 17.7 20.6 19.2 11.6 15.8 17.7 18.1 11.0 12.3 16.4 20.0 18.4 23.6 11.6 20.1 19.5 31.5 30.0 37.5 35.9 31.9 27.5 30.8 30.5 29.3 28.8 31.2 30.3 26.3 9.6 16.0 24.8 17.7 0.1 13.4 0.1 17.6 21.2 24.5 16.4 15.5 38.6 5.6 12.9 6.2 28.3 22.7 66.7 43.0 30.1 55.7 33.3 25.7 21.0 27.0 18.7 22.2 41.7 40.0 18.0 37.2 30.9 30.4 18.4 26.7 53.5 32.1 11.8 26.5 43.1 0.0 34.8 0.3 54.4 11.5 23.6 0.0 25.3 27.0 29.3 26.8 22.1 34.8 37.0 54.3 15.8 15.4 20.2 84.2 49.0 3.7 15.3 26.3 16.8 17.7 19.6 24.5 16.5 0.3 33.0 22.9 21.1 35.3 23.5 NACC1 "BEND8, BTBD14B, BTBD30, NAC-1, NAC1" ENSG00000160877 "Nucleus accumbens associated 1" Q96RE7 19 13116862-13141147 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021238, HPA062245, CAB069927" Enhanced Enhanced Nucleoplasm,Vesicles NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 47: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Vesicles "CAB069927: AB_1082966, HPA021238: AB_1845475, HPA062245: AB_2684724" "unprognostic (2.19e-1)" "unprognostic (9.20e-3)" "unprognostic (2.67e-2)" "unprognostic (2.84e-2)" "unprognostic (2.62e-1)" "unprognostic (7.75e-2)" "unprognostic (8.46e-3)" "unprognostic (1.10e-1)" "unprognostic (1.93e-1)" "unprognostic (8.46e-2)" "unprognostic (2.40e-2)" "unprognostic (3.04e-2)" "unprognostic (7.35e-2)" "unprognostic (2.80e-2)" "unprognostic (1.02e-1)" "unprognostic (1.97e-1)" "unprognostic (9.74e-2)" 12.6 19.5 31.0 14.6 19.2 8.8 10.3 7.1 26.6 9.7 0.0 17.3 13.3 18.4 7.9 27.6 11.9 6.4 20.9 25.7 7.4 14.8 20.5 16.7 12.1 13.4 15.9 7.7 12.2 10.7 14.8 12.4 15.1 14.6 6.6 3.7 15.8 11.2 24.2 17.4 16.0 7.7 8.9 15.9 16.0 17.0 20.6 11.3 14.0 7.9 8.8 15.0 12.6 16.4 98.8 110.0 28.0 59.6 15.0 17.7 74.9 47.4 34.2 42.4 32.4 114.8 40.4 50.9 104.1 39.8 37.3 49.0 34.8 80.7 16.2 89.1 52.5 32.4 87.9 84.7 35.5 52.0 82.3 28.8 28.0 46.1 24.7 36.5 50.2 46.4 72.5 19.8 22.9 206.1 82.9 39.6 123.6 28.9 101.7 47.8 32.9 49.5 28.2 101.1 58.2 37.7 49.6 64.9 39.1 29.8 59.3 46.4 76.7 94.6 58.8 67.2 87.0 53.4 88.1 42.4 99.7 52.8 58.9 0.0 0.2 0.0 0.2 0.1 0.1 0.1 0.3 0.1 0.1 0.0 0.2 0.1 0.3 0.0 0.1 0.2 0.1 0.1 31.0 19.2 7.1 26.6 25.7 7.4 13.4 15.9 15.1 8.9 20.6 16.4 4.9 0.0 1.7 6.2 5.6 12.1 7.5 11.8 2.8 16.6 11.5 7.5 2.1 12.8 8.5 16.5 2.1 19.0 12.9 22.7 7.9 12.3 2.3 10.9 8.9 8.1 4.9 12.2 7.2 8.8 20.0 5.2 10.7 17.6 10.2 13.3 8.6 18.0 21.1 26.9 5.9 16.2 14.2 9.6 9.6 2.0 4.4 8.8 5.4 3.7 10.5 12.0 10.3 5.5 5.4 21.7 11.1 9.4 5.6 16.5 14.0 15.0 5.9 7.7 6.6 7.5 7.0 11.1 15.6 8.4 13.9 27.1 7.9 15.2 15.4 17.2 NADK2 "C5orf33, FLJ30596, MNADK, NADKD1" ENSG00000152620 "NAD kinase 2, mitochondrial" Q4G0N4 5 36192589-36242279 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 11 "liver: 328.0" "Group enriched" "Detected in many" 5 "Astrocytes: 105.4;Early spermatids: 324.5;Hepatocytes: 211.9;Late spermatids: 154.9" "Cancer enhanced" "Detected in all" "liver cancer: 36.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038366, HPA038367, HPA061492" Enhanced Supported Mitochondria NA NA 30000 "Cluster 24: B-cells - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 23: Spermatids - Flagellum & Golgi organization" Mitochondria "HPA038366: AB_2675977, HPA038367: AB_10672743, HPA061492: AB_2684538" "unprognostic (1.15e-2)" "unprognostic (2.63e-2)" "unprognostic (3.01e-2)" "unprognostic (3.10e-3)" "unprognostic (1.64e-1)" "unprognostic (1.97e-2)" "unprognostic (4.06e-3)" "unprognostic (8.84e-2)" "unprognostic (3.32e-2)" "unprognostic (1.93e-3)" "unprognostic (1.09e-1)" "unprognostic (1.76e-1)" "unprognostic (9.73e-2)" "unprognostic (1.93e-1)" "unprognostic (1.58e-1)" "unprognostic (2.54e-2)" "unprognostic (1.75e-2)" 13.6 20.1 26.6 9.3 23.3 10.6 15.4 21.9 24.2 13.7 14.0 13.9 16.6 13.3 7.9 10.4 12.7 11.9 20.2 22.2 27.1 23.2 328.0 8.4 9.5 25.4 27.4 19.6 26.9 10.7 5.5 16.9 25.3 19.0 13.8 11.2 13.0 16.2 29.4 6.6 12.9 14.2 31.0 8.6 17.1 18.2 25.3 10.3 17.3 29.8 11.4 27.9 8.8 30.3 21.5 14.6 22.4 23.5 32.2 27.2 27.5 19.5 13.2 17.5 13.2 41.4 27.4 74.3 14.0 23.3 23.0 14.9 20.0 14.3 24.2 21.2 16.3 22.0 43.1 23.9 22.7 46.5 8.0 28.9 22.5 21.6 29.9 22.4 18.4 30.2 52.0 27.8 18.0 9.0 42.3 18.2 10.7 18.1 19.2 40.2 51.6 15.8 24.2 18.2 8.7 20.1 102.0 32.4 10.5 16.7 22.9 39.8 15.1 34.1 18.2 27.0 23.9 23.7 30.3 23.2 14.5 57.2 14.2 8.2 1.2 1.1 1.3 1.4 1.8 1.3 1.9 1.5 2.3 5.3 1.6 1.4 0.1 6.7 3.3 1.2 2.1 1.4 26.6 23.3 21.9 24.2 22.2 27.1 25.4 27.4 25.3 31.0 25.3 30.3 9.6 3.2 6.9 105.4 7.5 6.8 6.8 5.4 6.2 5.7 18.3 11.2 29.3 25.8 7.1 5.5 8.4 9.2 9.6 7.4 25.4 5.0 324.5 6.1 9.4 6.8 7.2 13.7 23.8 9.5 8.9 12.5 5.6 7.1 1.3 10.0 12.1 211.9 8.9 3.3 18.3 11.7 4.1 10.4 9.6 154.9 19.9 6.4 14.2 11.2 3.7 16.9 5.2 21.1 23.6 6.9 8.8 23.0 14.3 14.9 6.6 23.1 7.2 5.4 0.0 11.6 13.5 35.1 11.0 7.7 5.7 7.3 6.9 26.4 11.6 12.3 NALCN "bA430M15.1, CanIon, VGCNL1" ENSG00000102452 "Sodium leak channel, non-selective" Q8IZF0 13 101053776-101416508 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 13.1" "Group enriched" "Detected in some" 10 "Astrocytes: 125.4;Excitatory neurons: 265.8;Inhibitory neurons: 277.4;Oligodendrocyte precursor cells: 324.7;Oligodendrocytes: 477.4" "Cancer enhanced" "Detected in some" "glioma: 1.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "basophil: 2.6" "Lineage enriched" "Detected in single" 7 "granulocytes: 2.6" "Cell line enhanced" "Detected in many" "HaCaT: 14.2;HHSteC: 14.4;hTERT-RPE1: 11.0;TIME: 19.8;U-87 MG: 11.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031889, HPA031890, HPA031958" Approved NA NA "Cluster 17: Basophils - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA031889: AB_10669638, HPA031890: AB_10696056, HPA031958: AB_10601039" "unprognostic (4.66e-1)" "unprognostic (6.55e-3)" "unprognostic (1.86e-3)" "unprognostic (6.78e-3)" "unprognostic (1.16e-1)" "unprognostic (1.37e-3)" "unprognostic (8.11e-2)" "unprognostic (2.60e-1)" "unprognostic (7.72e-2)" "unprognostic (5.92e-2)" "unprognostic (1.25e-1)" "unprognostic (2.18e-1)" "unprognostic (1.58e-5)" "unprognostic (1.77e-3)" "unprognostic (5.44e-2)" "unprognostic (4.56e-2)" "unprognostic (1.92e-2)" 0.5 4.3 7.5 0.4 9.8 0.6 2.7 6.4 10.3 1.5 0.0 0.4 0.6 0.5 1.5 0.2 1.0 2.3 3.3 8.6 10.2 0.3 1.2 1.1 0.3 8.2 5.8 2.8 1.3 2.9 6.8 3.0 7.0 0.3 0.6 6.1 0.8 1.0 0.3 0.5 0.5 0.5 6.8 0.4 0.7 0.6 8.3 0.0 2.4 0.2 0.1 0.5 0.2 13.1 0.1 7.8 1.4 0.2 0.7 0.3 0.1 0.8 0.8 1.8 0.4 0.2 8.9 0.0 0.3 3.6 0.8 14.2 0.0 2.2 5.5 0.0 1.2 0.4 3.8 0.1 14.4 0.2 0.3 0.4 0.5 1.7 4.6 11.0 8.2 0.1 0.1 0.4 5.9 0.0 0.1 0.0 0.4 1.3 1.8 0.0 0.0 0.0 4.6 1.9 1.2 0.6 0.1 0.0 0.8 0.9 0.2 0.1 19.8 0.4 0.1 0.3 1.8 0.1 0.1 0.1 11.4 0.1 0.3 2.6 0.1 0.2 0.3 0.0 0.1 0.2 0.1 0.1 0.0 0.3 0.2 0.1 0.5 0.2 0.1 0.2 0.1 0.1 7.5 9.8 6.4 10.3 8.6 10.2 8.2 5.8 7.0 6.8 8.3 13.1 0.1 0.0 0.0 125.4 0.0 0.3 0.0 0.3 0.6 15.4 3.5 4.6 6.2 0.0 0.1 0.0 6.2 1.0 0.0 0.0 0.0 0.8 4.5 0.1 0.2 0.6 0.0 0.0 265.8 0.2 0.2 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 26.9 277.4 0.0 0.0 0.0 0.0 0.9 0.3 0.1 0.0 23.4 0.0 2.0 0.0 324.7 477.4 0.3 0.0 1.9 0.0 0.0 0.0 0.1 0.0 2.6 0.0 3.6 0.5 0.2 0.8 0.0 0.1 0.5 0.0 0.1 0.0 0.0 NANS SAS ENSG00000095380 "N-acetylneuraminate synthase" Q9NR45 9 98056732-98083077 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Intestinal goblet cells: 362.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019223 Approved Enhanced Nucleoplasm No No 410000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 4: Stomach - Digestion" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA019223: AB_1854298" "unprognostic (2.95e-1)" "unprognostic (5.10e-3)" "unprognostic (2.24e-2)" "prognostic favorable (1.71e-4)" "unprognostic (7.31e-3)" "unprognostic (1.23e-1)" "prognostic unfavorable (6.42e-4)" "unprognostic (2.08e-1)" "unprognostic (7.98e-2)" "unprognostic (2.28e-1)" "unprognostic (1.54e-2)" "unprognostic (1.12e-1)" "unprognostic (1.31e-2)" "unprognostic (1.64e-1)" "unprognostic (7.36e-2)" "unprognostic (3.62e-3)" "unprognostic (1.79e-1)" 39.4 28.9 16.2 49.3 15.0 67.8 36.5 13.8 18.2 49.9 29.8 133.5 52.2 28.5 33.5 51.4 29.4 34.2 46.3 15.1 17.0 32.8 67.0 45.9 59.5 16.2 17.2 26.2 67.6 20.4 42.5 31.7 18.4 106.4 129.2 8.3 120.0 19.7 34.2 29.2 47.8 29.0 15.1 53.3 76.1 27.2 17.2 18.8 27.3 17.4 60.5 47.5 41.5 17.2 387.9 111.8 32.5 94.5 64.0 68.8 70.5 120.9 93.7 96.3 78.3 134.8 53.6 118.1 57.2 133.3 101.9 134.1 61.0 103.6 80.0 95.7 91.0 70.3 128.4 271.9 176.3 80.3 55.3 58.4 69.1 102.9 116.4 111.8 104.3 57.9 129.9 119.8 71.2 265.0 54.1 114.9 56.2 277.5 143.3 103.4 89.0 121.5 78.2 116.6 65.7 34.4 77.8 414.4 107.2 35.8 137.6 85.3 274.2 74.8 72.5 193.4 125.8 110.7 99.3 45.7 88.4 95.9 59.6 30.9 190.9 29.5 34.9 237.6 53.4 55.6 45.5 36.8 194.7 54.9 48.8 33.7 77.4 38.9 217.0 178.8 58.3 91.4 16.2 15.0 13.8 18.2 15.1 17.0 16.2 17.2 18.4 15.1 17.2 17.2 46.7 28.9 54.9 3.6 57.0 70.1 134.0 183.0 30.7 11.4 61.6 45.5 25.3 42.9 206.3 22.0 18.8 86.7 50.2 234.3 70.5 49.4 42.8 63.4 37.9 63.4 64.9 18.7 6.7 100.7 159.2 50.6 99.4 55.8 43.8 29.5 34.2 33.6 160.0 10.1 7.2 362.7 95.6 67.7 107.6 71.5 32.3 89.8 129.9 6.5 53.1 14.1 14.4 2.0 3.1 70.9 181.0 26.4 141.1 213.6 66.5 68.3 204.5 8.0 13.1 32.9 91.3 10.5 21.9 42.0 61.7 150.8 50.6 44.6 260.1 223.3 NAP1L4 NAP2 ENSG00000205531 "Nucleosome assembly protein 1 like 4" Q99733 11 2944431-2992377 "Plasma proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB011567 Approved Supported Nucleoplasm NA NA 3100000 "Cluster 46: Basophils - DNA binding" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "CAB011567: AB_776638" "unprognostic (1.61e-1)" "prognostic favorable (9.77e-4)" "unprognostic (8.99e-2)" "unprognostic (9.64e-3)" "unprognostic (2.96e-3)" "unprognostic (2.24e-2)" "prognostic unfavorable (1.68e-7)" "unprognostic (1.80e-1)" "unprognostic (6.44e-2)" "unprognostic (1.77e-1)" "unprognostic (6.73e-2)" "unprognostic (2.31e-1)" "unprognostic (6.10e-3)" "unprognostic (1.19e-1)" "unprognostic (1.29e-1)" "prognostic favorable (1.55e-4)" "unprognostic (1.54e-1)" 39.6 43.5 44.3 36.1 59.2 50.3 41.3 53.0 178.1 46.7 70.3 60.3 20.1 45.4 17.3 79.6 41.2 32.5 111.4 41.3 52.1 63.7 56.2 40.5 65.7 57.2 53.8 42.9 38.0 63.5 61.4 36.8 60.2 51.9 34.2 38.6 66.4 32.1 146.1 49.0 53.8 39.1 52.2 59.0 56.6 87.4 56.4 78.8 44.6 110.7 75.8 61.9 52.1 72.2 82.8 59.9 81.7 65.7 83.9 92.4 37.7 159.8 104.1 145.4 132.5 129.7 208.4 149.5 95.3 98.0 15.1 140.0 21.9 136.3 166.8 159.2 57.5 106.7 151.4 168.2 57.7 93.0 110.5 77.8 65.1 78.6 59.1 12.0 88.9 77.6 139.3 150.7 128.0 74.5 206.4 4.2 199.8 98.9 75.2 101.4 98.1 117.0 12.2 131.7 121.4 104.3 80.5 118.1 78.3 82.5 7.3 7.4 67.8 112.5 104.4 152.4 13.8 79.3 136.5 201.5 8.4 66.0 75.3 67.5 22.9 32.6 42.3 24.0 39.9 24.7 51.9 53.0 27.2 28.4 45.7 52.1 14.5 57.6 30.4 25.0 70.5 48.0 44.3 59.2 53.0 178.1 41.3 52.1 57.2 53.8 60.2 52.2 56.4 72.2 53.6 44.8 49.8 56.2 64.3 70.1 67.4 76.9 83.1 80.4 54.6 48.3 200.4 42.9 69.0 75.4 45.9 103.8 99.4 37.2 97.8 78.7 97.0 107.7 65.9 55.4 45.4 168.7 36.9 50.4 109.2 56.6 54.0 91.1 74.6 100.6 43.5 50.0 47.3 65.6 56.6 41.4 67.1 30.8 44.7 142.6 48.1 49.7 35.6 38.4 65.3 67.5 95.8 60.8 125.3 74.1 26.8 50.0 100.7 76.1 39.8 76.9 92.6 68.1 46.0 58.8 64.7 166.1 129.0 102.3 66.9 91.3 123.8 79.7 55.1 83.7 NAV1 "DKFZp781D0314, FLJ12560, FLJ14203, KIAA1151, MGC14961, POMFIL3, steerin-1" ENSG00000134369 "Neuron navigator 1" Q8NEY1 1 201622885-201826969 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 169.1;Inhibitory neurons: 161.7;Oligodendrocyte precursor cells: 713.8;Oligodendrocytes: 224.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 3.4;myeloid DC: 2.1" "Group enriched" "Detected in many" 5 "dendritic cells: 2.1;granulocytes: 3.4" "Cell line enhanced" "Detected in many" "TIME: 187.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012302, HPA018127, HPA027887" Enhanced Approved Microtubules NA NA "Cluster 46: Basophils - DNA binding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 68: Oligodendrocytes - Mixed function" Microtubules "CAB012302: AB_776716, HPA018127: AB_1854317, HPA027887: AB_10601040" "unprognostic (2.14e-1)" "unprognostic (1.82e-1)" "unprognostic (4.12e-2)" "unprognostic (3.33e-2)" "unprognostic (1.14e-1)" "unprognostic (3.87e-1)" "unprognostic (1.79e-1)" "unprognostic (3.45e-1)" "unprognostic (9.10e-2)" "unprognostic (5.63e-2)" "unprognostic (4.68e-1)" "unprognostic (8.24e-2)" "prognostic unfavorable (3.10e-6)" "unprognostic (3.45e-2)" "unprognostic (2.16e-1)" "unprognostic (1.89e-1)" "unprognostic (1.44e-1)" 19.6 2.7 17.4 8.2 18.3 1.6 15.2 8.0 17.7 11.7 0.0 12.3 3.7 10.1 4.3 8.6 7.2 7.5 26.6 17.5 20.3 4.6 1.9 11.1 4.1 24.6 17.9 3.7 4.4 5.2 5.2 11.8 15.1 7.5 5.4 5.4 7.8 6.7 4.8 7.7 6.2 10.3 9.9 3.6 5.3 4.4 21.8 2.8 9.4 6.7 3.7 14.9 12.6 32.5 1.6 2.9 29.0 3.8 84.3 69.5 51.7 44.6 43.0 35.5 30.9 0.0 15.7 0.6 0.7 61.4 19.4 21.5 22.0 14.9 28.4 2.5 3.2 1.4 5.6 0.0 22.5 0.2 19.1 30.6 5.4 62.4 36.0 94.9 80.7 1.8 0.8 2.6 29.8 0.4 0.0 0.1 42.4 0.7 1.7 3.9 65.0 9.3 4.8 4.3 21.9 4.5 11.1 47.6 14.5 19.2 0.4 1.2 187.8 54.5 11.1 54.7 39.4 8.1 2.3 0.2 59.2 5.9 47.5 3.4 0.5 0.1 0.2 0.3 0.1 0.3 0.2 0.0 2.1 0.3 0.2 0.1 0.0 0.1 0.3 0.5 0.0 0.3 17.4 18.3 8.0 17.7 17.5 20.3 24.6 17.9 15.1 9.9 21.8 32.5 77.4 3.2 1.5 169.1 3.1 11.0 2.2 5.9 8.0 34.6 4.8 4.3 29.2 1.5 4.8 12.9 0.0 14.9 0.9 4.7 0.0 13.0 3.6 1.6 6.4 39.3 52.8 1.7 98.2 8.3 54.1 45.8 8.2 4.4 17.7 54.5 21.0 0.7 14.5 25.2 161.7 3.4 6.1 18.3 15.8 3.8 10.8 15.1 23.2 69.3 60.6 11.8 1.0 713.8 224.6 21.7 4.2 0.7 4.9 2.3 0.9 0.6 3.5 4.0 6.6 119.3 18.8 0.6 2.6 16.9 7.0 15.7 2.0 6.6 5.0 3.2 NAXE "AIBP, APOA1BP, MGC119143, MGC119144, MGC119145, YJEFN1" ENSG00000163382 "NAD(P)HX epimerase" Q8NCW5 1 156591756-156609507 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted secreted proteins" "Lipid transport, Transport" Isomerase "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 136.7;Distal tubular cells: 201.5;Ductal cells: 112.8;Exocrine glandular cells: 100.1;Proximal tubular cells: 219.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043766, HPA048164" Enhanced Approved Nucleoplasm,Vesicles,Cytosol "Secreted to blood" NA NA 3300000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Vesicles, Cytosol" "HPA043766: AB_2678660, HPA048164: AB_2680294" "unprognostic (1.27e-1)" "unprognostic (2.34e-2)" "unprognostic (2.49e-1)" "prognostic unfavorable (4.94e-4)" "unprognostic (7.38e-2)" "unprognostic (5.32e-2)" "unprognostic (2.46e-3)" "unprognostic (2.60e-1)" "unprognostic (1.72e-1)" "unprognostic (3.08e-3)" "unprognostic (3.23e-2)" "unprognostic (3.14e-2)" "unprognostic (2.15e-2)" "unprognostic (8.05e-2)" "unprognostic (7.43e-2)" "unprognostic (2.09e-1)" "unprognostic (3.81e-1)" 47.1 74.8 61.0 20.9 63.7 22.2 47.9 66.1 69.6 56.8 71.1 62.9 45.5 68.8 88.7 58.0 59.5 26.5 111.1 60.9 64.3 83.8 86.5 43.6 27.0 62.7 64.8 46.5 69.7 104.7 70.0 23.7 61.8 62.5 41.6 17.4 53.9 48.3 71.8 55.8 48.3 39.7 64.7 43.2 67.5 40.8 63.5 30.6 59.8 68.2 34.3 55.0 47.8 70.5 114.2 155.4 43.9 84.4 64.0 43.8 55.5 29.5 62.3 69.5 72.6 130.6 76.8 62.4 113.4 52.5 55.9 111.1 49.4 99.0 47.5 81.2 98.5 58.1 76.2 86.1 75.1 60.0 60.9 44.2 123.7 87.9 81.9 53.4 95.4 104.7 54.7 70.1 71.6 209.6 83.3 98.0 43.1 158.1 118.2 87.7 40.2 212.6 93.0 93.6 114.7 102.9 90.4 172.4 141.6 66.4 178.3 117.5 51.1 45.1 64.8 64.6 70.6 180.1 110.3 53.0 63.1 37.0 70.4 25.4 96.3 52.9 121.2 111.3 121.3 236.2 109.4 124.3 89.1 186.5 122.8 114.9 11.4 141.3 89.1 225.7 110.1 186.6 61.0 63.7 66.1 69.6 60.9 64.3 62.7 64.8 61.8 64.7 63.5 70.5 29.5 41.7 32.9 0.0 14.8 0.0 0.0 0.0 0.0 0.0 87.5 96.0 0.0 0.0 23.5 68.0 0.0 136.7 28.7 0.0 201.5 112.8 0.0 27.3 29.9 18.4 0.0 0.0 0.0 100.1 43.1 27.2 0.0 32.0 5.1 53.5 0.0 0.0 92.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.5 0.0 0.0 40.8 0.0 0.0 0.0 0.0 91.0 0.0 0.0 6.2 0.0 0.0 219.6 11.7 0.0 0.0 0.0 24.5 0.0 0.0 0.0 0.0 81.3 13.4 48.1 0.0 0.0 NCAM2 "MGC51008, NCAM21" ENSG00000154654 "Neural cell adhesion molecule 2" O15394 21 20998409-21543329 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 12.0;brain: 26.0" "Group enriched" "Detected in some" 19 "Astrocytes: 713.0;Excitatory neurons: 866.5;Inhibitory neurons: 909.2;Oligodendrocyte precursor cells: 1729.1;Oligodendrocytes: 1526.6" "Group enriched" "Detected in some" 4 "breast cancer: 2.6;glioma: 5.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "T-47d: 92.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030900, HPA030901" Enhanced Supported Supported "Nuclear bodies,Plasma membrane" No No 120000000 "Cluster 65: Brain - Ion transport" "Cluster 6: T47d - Mammary gland" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nuclear bodies, Plasma membrane" "HPA030900: AB_10602037, HPA030901: AB_2673650" "unprognostic (9.70e-2)" "unprognostic (1.08e-1)" "unprognostic (1.47e-1)" "unprognostic (2.54e-2)" "unprognostic (1.85e-1)" "unprognostic (1.81e-1)" "unprognostic (1.37e-2)" "unprognostic (3.01e-2)" "unprognostic (5.90e-2)" "unprognostic (1.62e-1)" "unprognostic (1.31e-1)" "unprognostic (5.61e-1)" "unprognostic (3.07e-4)" "unprognostic (2.47e-4)" "unprognostic (1.62e-1)" "unprognostic (8.05e-2)" "unprognostic (1.35e-3)" 0.7 12.0 14.1 0.9 19.0 0.0 1.6 8.4 17.5 1.6 0.0 2.0 0.2 1.0 0.5 0.5 0.6 1.2 2.0 21.3 22.7 0.2 6.7 2.8 0.1 8.6 14.4 0.3 0.2 0.6 0.8 0.5 8.8 0.9 1.0 1.2 0.7 1.0 0.4 0.8 0.7 1.4 8.8 0.8 0.6 6.3 26.0 0.1 0.3 0.8 0.2 0.6 1.2 21.6 0.0 0.0 0.5 0.0 4.6 4.7 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.5 1.3 0.0 0.5 1.3 0.0 2.2 0.0 0.1 11.3 0.0 3.5 0.0 0.4 0.0 0.0 11.4 2.4 0.2 15.4 0.2 0.0 0.4 0.0 0.0 1.0 0.0 4.7 0.0 0.0 0.0 5.3 0.0 0.8 0.6 0.1 92.1 7.2 0.0 1.3 0.9 0.1 0.0 0.6 0.0 0.0 2.5 0.0 22.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.1 19.0 8.4 17.5 21.3 22.7 8.6 14.4 8.8 8.8 26.0 21.6 0.4 3.2 1.3 713.0 0.1 0.5 0.3 0.0 0.0 1.0 2.0 1.4 1.8 0.0 0.0 0.0 0.0 1.7 0.3 0.0 0.0 0.0 57.6 0.3 6.1 0.4 0.0 0.0 866.5 0.0 0.4 4.8 0.0 0.2 0.0 0.2 2.2 0.0 0.3 0.0 909.2 0.0 0.0 0.0 0.3 24.7 0.9 0.1 1.8 30.9 0.0 1.0 0.0 1729.1 1526.6 0.0 0.0 0.4 0.0 0.7 0.0 0.1 0.0 0.1 0.0 2.4 1.6 3.7 9.6 0.1 0.1 0.3 0.2 1.9 0.0 0.2 NCAPD2 "CAP-D2, CNAP1, hCAP-D2, KIAA0159" ENSG00000010292 "Non-SMC condensin I complex subunit D2" Q15021 12 6493356-6531955 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA condensation, Mitosis" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 76.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 48.0;Late spermatids: 34.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012423, HPA036947, HPA037363" Approved Supported Nucleoplasm,Nucleoli,Cytosol NA Yes 34000 "Cluster 44: Non-specific - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "Nucleoplasm, Nucleoli" "CAB012423: , HPA036947: AB_10671367, HPA037363: AB_10672483" "unprognostic (1.51e-1)" "unprognostic (1.88e-1)" "unprognostic (2.20e-1)" "unprognostic (1.31e-2)" "unprognostic (1.03e-2)" "unprognostic (7.84e-2)" "prognostic unfavorable (1.79e-8)" "unprognostic (2.73e-3)" "unprognostic (1.45e-2)" "unprognostic (5.00e-2)" "unprognostic (5.41e-3)" "unprognostic (4.53e-1)" "prognostic unfavorable (1.13e-7)" "unprognostic (4.80e-3)" "unprognostic (1.18e-1)" "unprognostic (4.53e-1)" "unprognostic (8.75e-2)" 8.3 7.4 7.3 21.5 11.4 35.5 10.9 9.9 8.3 10.2 7.4 17.9 17.0 10.7 10.6 15.9 11.2 9.8 7.6 7.2 8.0 7.4 4.8 10.6 38.1 11.0 10.0 8.0 7.7 11.3 5.5 17.5 11.7 9.4 20.4 11.1 11.8 10.2 7.9 21.9 16.0 13.4 8.4 16.1 12.1 18.2 10.2 76.8 11.3 10.2 44.8 10.1 9.3 13.9 125.3 99.3 134.6 97.9 29.9 28.4 159.2 76.1 69.8 138.3 109.1 123.5 150.8 135.8 24.2 63.2 126.7 128.6 188.0 105.4 194.1 214.1 92.8 112.2 113.8 79.4 12.5 145.0 96.5 20.5 31.6 112.4 107.8 61.9 89.9 94.0 71.0 63.4 104.7 79.6 162.2 73.8 207.5 129.9 78.2 153.7 260.6 77.7 39.5 64.1 54.0 61.9 121.5 64.9 44.3 189.1 27.0 101.7 51.0 94.1 149.6 60.8 168.4 45.3 51.7 181.0 55.7 92.2 126.1 11.0 1.7 3.7 7.1 2.8 5.3 5.1 6.4 7.3 3.4 3.5 7.3 7.3 1.4 8.1 2.2 4.1 8.3 3.9 7.3 11.4 9.9 8.3 7.2 8.0 11.0 10.0 11.7 8.4 10.2 13.9 4.3 6.4 7.4 4.9 11.0 3.6 3.8 4.4 17.1 3.7 4.7 6.9 4.1 5.7 3.4 1.8 8.4 13.5 8.9 7.3 0.0 4.5 18.3 5.3 6.3 5.4 1.2 48.0 5.6 3.7 17.8 6.4 7.1 5.8 3.8 20.0 8.9 3.3 10.1 5.0 5.0 9.9 6.1 16.4 4.4 34.3 5.9 10.8 0.0 2.8 9.5 11.8 15.5 2.5 17.8 5.3 4.6 6.0 22.6 4.1 6.0 2.4 4.2 8.4 0.0 4.2 5.2 21.3 13.7 19.3 3.4 6.3 12.0 6.1 14.7 4.1 NCF2 "NOXA2, p67phox" ENSG00000116701 "Neutrophil cytosolic factor 2" P19878 1 183555562-183590876 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Chronic granulomatous disease, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 191.9;lung: 74.6;lymphoid tissue: 78.8" "Group enriched" "Detected in many" 5 "Ductal cells: 68.6;Hofbauer cells: 212.0;Kupffer cells: 137.9;Langerhans cells: 129.5;Macrophages: 194.4;monocytes: 223.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 1313.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 26.4;HMC-1: 21.4;hTERT-HME1: 51.6;RPMI-8226: 20.0;U-2 OS: 50.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA002327, HPA006040, CAB022160" Enhanced Supported Cytosol NA NA 12000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol "CAB022160: , HPA002327: AB_1079550, HPA006040: AB_1854906" "unprognostic (4.97e-2)" "unprognostic (3.48e-2)" "unprognostic (2.40e-2)" "unprognostic (1.22e-3)" "unprognostic (5.83e-3)" "unprognostic (4.04e-2)" "prognostic unfavorable (7.91e-6)" "unprognostic (1.29e-1)" "unprognostic (2.45e-1)" "unprognostic (2.33e-1)" "unprognostic (5.70e-2)" "unprognostic (2.01e-1)" "unprognostic (1.57e-2)" "unprognostic (1.61e-1)" "unprognostic (1.41e-2)" "unprognostic (8.24e-2)" "unprognostic (2.36e-2)" 29.9 5.8 2.7 76.9 3.0 191.9 7.0 3.2 14.6 9.5 4.5 10.4 8.5 4.1 1.6 7.6 8.0 23.8 5.6 2.3 3.9 3.7 12.7 74.6 17.3 6.2 4.2 2.1 4.6 2.8 2.7 39.7 6.8 2.9 12.5 0.8 6.6 3.5 3.7 15.9 12.4 20.4 4.5 78.8 5.8 2.1 12.0 11.3 3.0 11.5 16.9 24.2 5.9 7.8 26.4 0.8 0.0 0.0 0.0 0.0 0.3 1.9 2.4 3.4 1.6 0.2 0.8 3.2 4.3 0.8 0.6 14.3 0.1 19.0 3.1 16.2 0.0 0.0 7.3 6.0 0.0 2.0 21.4 0.0 4.1 3.4 51.6 2.2 0.0 0.1 0.0 5.6 5.8 0.2 0.2 1.1 0.4 1.5 1.5 7.0 2.2 20.0 0.8 0.2 0.0 0.1 0.3 0.1 0.9 1.7 2.8 9.1 1.2 0.1 50.2 0.0 4.9 0.9 1.4 0.6 0.4 10.3 0.0 199.5 489.2 1313.6 1.0 348.8 1.6 14.1 4.0 1.6 246.0 10.8 2.2 1.3 799.7 2.1 326.1 13.5 11.1 298.9 2.7 3.0 3.2 14.6 2.3 3.9 6.2 4.2 6.8 4.5 12.0 7.8 0.7 9.6 15.7 0.0 8.4 5.5 0.2 13.7 1.8 0.3 0.1 0.3 1.3 7.2 17.3 0.0 0.0 1.0 9.6 0.1 3.9 68.6 1.1 1.9 0.5 3.5 0.0 1.7 0.3 3.9 1.1 2.0 0.5 1.3 7.6 0.0 3.3 1.0 212.0 0.0 0.3 0.2 26.4 137.9 129.5 2.9 0.6 194.4 7.2 3.7 223.6 0.0 6.2 0.0 0.2 27.3 2.6 0.0 3.2 0.6 0.0 0.3 32.0 0.7 13.1 0.7 6.8 0.1 0.6 0.6 4.3 1.9 3.7 0.2 0.0 1.2 NCF4 "p40phox, SH3PXD4" ENSG00000100365 "Neutrophil cytosolic factor 4" Q15080 22 36860988-36878017 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Chronic granulomatous disease, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 180.2;lymphoid tissue: 162.3" "Cell type enhanced" "Detected in many" "B-cells: 70.9;granulocytes: 74.1;Hofbauer cells: 198.4;Kupffer cells: 85.3;Langerhans cells: 55.8;Macrophages: 85.7;Plasma cells: 68.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 657.3;eosinophil: 750.1;neutrophil: 1235.8" "Lineage enriched" "Detected in all" 7 "granulocytes: 1235.8" "Cell line enhanced" "Detected in some" "HEL: 78.3;HMC-1: 396.0;NB-4: 148.7;REH: 76.5;RPMI-8226: 144.0;THP-1: 137.9;U-937: 76.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB010146, HPA036156, HPA057975" Enhanced Enhanced Cytosol NA NA 7800 "Cluster 5: Granulocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" Cytosol "CAB010146: AB_627989, HPA036156: AB_2674974, HPA057975: AB_2683568" "unprognostic (3.27e-2)" "unprognostic (1.55e-2)" "unprognostic (2.68e-2)" "unprognostic (1.36e-3)" "unprognostic (1.35e-1)" "unprognostic (2.78e-3)" "unprognostic (4.20e-2)" "unprognostic (3.69e-2)" "unprognostic (4.03e-2)" "unprognostic (2.70e-1)" "unprognostic (3.27e-2)" "unprognostic (2.54e-1)" "prognostic unfavorable (7.06e-8)" "unprognostic (3.60e-1)" "unprognostic (2.23e-2)" "unprognostic (1.19e-1)" "unprognostic (2.42e-1)" 29.5 14.4 4.8 43.1 5.0 180.2 12.7 4.9 7.5 4.6 6.4 19.2 11.7 4.5 1.0 7.2 13.9 13.0 9.4 4.9 5.4 8.9 10.1 45.1 39.8 6.8 5.9 3.3 4.1 1.4 5.3 24.3 6.4 7.4 11.8 0.1 10.7 4.5 3.6 4.9 42.6 10.5 5.8 162.3 9.3 1.8 8.6 12.9 8.1 7.1 33.5 18.7 7.2 7.1 1.1 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 28.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 6.6 0.0 78.3 0.0 0.0 0.0 12.8 396.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 26.8 0.0 0.8 0.0 148.7 0.0 0.0 0.0 76.5 0.0 144.0 0.0 0.2 0.0 0.0 0.0 1.2 0.0 0.0 0.0 137.9 0.0 0.0 0.2 0.1 0.2 0.5 0.1 23.7 0.1 76.8 0.1 657.3 184.6 750.1 2.3 92.5 9.8 108.2 32.0 6.9 86.1 85.9 1.9 2.1 1235.8 4.4 62.0 100.7 96.3 106.3 4.8 5.0 4.9 7.5 4.9 5.4 6.8 5.9 6.4 5.8 8.6 7.1 1.5 3.2 18.7 0.0 70.9 2.8 2.2 1.3 0.6 0.0 3.1 2.5 2.1 0.0 5.8 1.8 0.0 3.2 21.1 1.3 0.0 0.6 0.2 0.2 0.1 3.6 0.0 28.8 0.0 3.1 16.0 1.8 2.0 0.4 74.1 0.0 1.4 0.7 198.4 0.0 0.0 0.5 2.0 85.3 55.8 1.0 0.6 85.7 14.2 3.7 38.5 0.0 3.1 0.0 0.1 0.9 22.5 0.0 68.2 0.3 0.2 0.2 0.9 0.3 0.0 0.5 1.6 0.0 0.4 0.5 2.3 13.0 17.5 0.7 1.7 4.3 NCK2 NCKbeta ENSG00000071051 "NCK adaptor protein 2" O43639 2 105744912-105894274 "Plasma proteins, Predicted intracellular proteins" "Translation regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 184.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016116, HPA031004" Approved NA NA 87000 "Cluster 35: T-regs - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 24: Non-specific - Transcription regulation" "CAB016116: AB_2150588, HPA031004: AB_10795571" "unprognostic (2.39e-1)" "unprognostic (3.48e-1)" "unprognostic (6.67e-2)" "unprognostic (4.43e-2)" "unprognostic (1.66e-1)" "unprognostic (1.53e-1)" "unprognostic (5.85e-3)" "unprognostic (4.04e-2)" "unprognostic (4.88e-2)" "unprognostic (1.22e-1)" "unprognostic (9.62e-2)" "unprognostic (2.31e-1)" "unprognostic (1.50e-1)" "unprognostic (8.24e-2)" "unprognostic (2.14e-2)" "unprognostic (7.21e-3)" "unprognostic (4.22e-2)" 37.8 19.7 18.6 20.5 19.2 17.6 33.6 26.3 29.0 36.4 16.7 39.1 54.7 29.7 18.9 68.8 25.4 19.0 31.9 27.9 18.4 28.9 11.1 37.1 27.6 21.8 22.4 25.1 39.8 13.6 19.7 36.8 22.0 24.7 16.4 10.3 46.8 18.7 53.5 33.4 51.7 17.9 22.5 52.0 40.3 27.3 23.9 18.6 28.3 27.2 19.1 35.6 50.4 20.4 25.8 20.2 51.6 23.9 15.0 10.7 73.3 19.0 25.0 21.6 12.5 58.8 20.9 11.2 23.4 24.2 31.0 25.1 21.9 47.7 14.6 79.5 24.5 5.0 9.4 37.8 39.2 28.1 9.8 21.4 34.0 23.5 30.0 18.7 22.0 27.3 7.7 38.5 17.9 21.7 29.3 48.2 28.8 21.6 23.0 23.4 36.2 41.7 28.1 51.2 32.9 45.4 14.4 37.2 184.4 30.4 13.6 70.3 25.0 37.9 55.2 1.0 27.2 28.8 19.6 3.8 16.7 24.5 61.6 26.2 1.0 12.5 7.0 1.0 9.2 7.7 13.1 11.8 1.2 11.1 13.6 12.5 9.3 11.9 1.0 1.8 24.5 5.0 18.6 19.2 26.3 29.0 27.9 18.4 21.8 22.4 22.0 22.5 23.9 20.4 41.8 16.0 7.9 28.1 32.8 17.6 13.9 14.2 7.4 13.5 27.1 35.9 21.3 71.4 9.6 16.5 12.5 39.0 30.3 31.2 7.9 28.1 15.5 18.0 21.8 23.7 19.2 2.5 60.0 18.8 15.2 16.2 13.3 19.9 5.7 33.0 18.2 2.3 26.0 82.4 48.4 23.1 18.3 14.2 13.9 9.2 23.6 18.7 10.6 77.8 10.5 61.4 18.6 24.6 18.3 29.9 29.2 28.2 15.8 17.7 51.3 8.4 18.9 4.6 32.9 33.1 54.4 4.2 9.6 10.7 16.8 29.7 52.4 18.1 31.2 30.0 NCLN "NET59, NICALIN" ENSG00000125912 Nicalin Q969V3 19 3185563-3209575 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Theca cells: 115.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006625 Approved Approved "Nucleoplasm,Lipid droplets" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 18: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Lipid droplets" Nucleoplasm "HPA006625: AB_1079453" "unprognostic (4.32e-2)" "unprognostic (1.88e-1)" "unprognostic (1.89e-1)" "prognostic favorable (1.19e-4)" "unprognostic (8.55e-2)" "unprognostic (2.79e-1)" "prognostic unfavorable (2.15e-4)" "unprognostic (9.27e-2)" "unprognostic (1.22e-1)" "unprognostic (9.38e-2)" "unprognostic (2.02e-2)" "unprognostic (1.26e-3)" "prognostic unfavorable (8.37e-5)" "prognostic favorable (8.82e-5)" "unprognostic (1.75e-1)" "unprognostic (1.25e-1)" "unprognostic (7.38e-2)" 25.8 62.4 19.7 16.2 18.5 33.3 22.3 18.6 25.2 23.1 13.9 36.5 31.1 25.9 4.3 31.0 23.4 6.9 28.0 22.2 15.7 29.5 59.8 33.1 12.7 20.4 18.8 22.0 53.6 11.0 23.5 7.5 18.6 28.9 8.7 3.5 22.9 8.0 29.2 25.8 35.8 8.6 17.4 42.8 29.7 21.8 21.1 8.6 24.4 10.5 6.6 26.3 21.7 17.5 70.8 74.2 21.6 60.3 20.3 15.4 55.4 84.5 33.2 57.5 45.5 103.6 36.8 43.3 67.0 49.4 37.8 87.2 24.7 57.1 12.7 57.4 61.3 31.7 46.2 73.2 41.1 56.8 51.3 29.0 36.2 46.4 24.7 15.2 31.7 41.7 84.1 41.4 25.6 59.3 48.9 64.1 59.3 43.2 63.6 77.8 23.2 71.9 36.5 42.6 45.3 47.1 31.1 56.2 50.3 10.3 38.3 61.9 47.6 45.4 45.8 77.3 100.4 59.0 58.1 36.0 51.1 71.5 72.7 1.4 13.4 9.8 7.1 13.1 5.8 5.4 4.3 7.9 9.2 4.5 4.6 6.2 7.6 4.8 5.6 18.8 4.2 9.6 19.7 18.5 18.6 25.2 22.2 15.7 20.4 18.8 18.6 17.4 21.1 17.5 15.3 16.0 14.7 12.1 19.8 8.3 9.4 18.2 5.7 15.1 15.6 11.9 10.2 15.7 14.8 11.0 10.4 20.4 26.0 71.0 3.9 31.0 15.0 11.3 15.6 14.3 12.6 12.4 13.6 37.4 49.3 14.9 30.5 17.4 15.9 31.1 12.8 43.8 39.3 23.5 14.6 41.2 14.2 18.8 9.2 49.1 9.3 18.1 14.2 8.4 19.2 5.8 14.4 9.0 10.3 35.8 45.3 9.1 51.7 22.0 75.7 11.7 10.5 13.2 13.1 11.8 16.9 13.6 20.1 12.4 12.5 17.0 12.0 115.1 72.7 14.2 NCOA2 "bHLHe75, GRIP1, KAT13C, NCoA-2, TIF2" ENSG00000140396 "Nuclear receptor coactivator 2" Q15596 8 70109782-70403808 "Cancer-related genes, Disease related genes, Metabolic proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" Activator "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 161.6;Excitatory neurons: 158.9;Inhibitory neurons: 314.8;Microglial cells: 233.3;Oligodendrocyte precursor cells: 249.8;Oligodendrocytes: 186.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060243 Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 29: U-266 - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Nuclear bodies" "HPA060243: AB_2684229" "unprognostic (9.79e-3)" "unprognostic (1.40e-1)" "unprognostic (2.72e-1)" "unprognostic (4.94e-3)" "unprognostic (1.91e-2)" "unprognostic (2.18e-3)" "unprognostic (1.30e-1)" "unprognostic (6.77e-2)" "unprognostic (2.06e-1)" "unprognostic (7.00e-2)" "unprognostic (2.20e-2)" "unprognostic (2.63e-2)" "prognostic favorable (5.08e-4)" "unprognostic (2.52e-1)" "unprognostic (3.35e-1)" "unprognostic (1.07e-1)" "unprognostic (1.76e-1)" 8.4 8.9 8.9 9.9 10.5 23.3 13.4 8.9 10.0 10.0 1.5 10.6 11.6 10.1 29.6 15.3 10.9 8.9 15.0 13.6 13.2 14.4 23.8 10.0 11.6 8.0 6.8 16.2 7.3 15.2 7.3 12.1 7.7 12.9 10.6 26.1 11.3 12.1 8.3 10.5 12.1 9.0 4.6 12.4 10.9 14.7 9.9 15.3 12.1 15.9 12.5 10.0 9.9 6.1 13.7 16.9 18.2 10.3 16.2 16.5 18.6 7.8 7.8 5.9 5.5 8.6 15.6 16.3 3.1 14.3 9.7 8.0 22.5 10.7 6.5 38.7 17.9 28.5 8.5 13.8 8.5 5.8 7.2 14.5 11.7 7.9 11.3 9.2 4.0 11.7 9.2 24.0 6.9 13.7 14.5 5.8 9.6 15.7 7.9 14.1 7.6 10.3 9.3 22.5 13.8 10.2 13.4 7.1 11.0 12.7 16.7 10.5 5.3 8.4 10.6 10.8 4.2 31.5 17.3 15.4 8.6 7.6 12.5 3.1 1.6 2.2 2.2 2.3 1.5 1.3 1.3 1.9 1.5 2.1 1.5 1.6 5.7 1.4 5.2 0.6 2.0 1.2 8.9 10.5 8.9 10.0 13.6 13.2 8.0 6.8 7.7 4.6 9.9 6.1 20.9 12.8 25.1 161.6 27.3 16.2 8.6 10.8 17.6 25.8 29.5 17.5 34.1 28.6 25.8 25.8 52.1 22.1 26.9 30.8 11.7 9.3 6.4 23.6 26.4 17.7 25.2 28.8 158.9 12.4 12.5 21.6 21.4 38.0 22.2 23.2 22.1 65.9 17.4 74.0 314.8 17.4 10.2 46.8 17.8 7.6 19.9 28.1 21.4 233.3 23.1 14.3 19.6 249.8 186.0 12.8 14.8 22.2 49.9 15.5 22.7 17.6 19.0 33.4 26.3 22.5 20.2 13.3 16.5 18.8 21.5 31.7 36.6 10.9 17.0 15.8 NCOA5 "bA465L10.6, CIA" ENSG00000124160 "Nuclear receptor coactivator 5" Q9HCD5 20 46060991-46089962 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050231 Uncertain Supported "Nucleoplasm,Actin filaments" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Actin filaments" "HPA050231: AB_2681058" "unprognostic (1.78e-1)" "unprognostic (1.54e-1)" "unprognostic (2.43e-2)" "unprognostic (7.93e-2)" "unprognostic (2.30e-1)" "unprognostic (1.43e-2)" "prognostic unfavorable (1.41e-5)" "prognostic favorable (8.07e-4)" "unprognostic (2.32e-1)" "unprognostic (7.75e-2)" "prognostic favorable (1.09e-4)" "unprognostic (7.46e-2)" "unprognostic (4.40e-1)" "unprognostic (2.06e-2)" "unprognostic (1.07e-1)" "unprognostic (8.78e-2)" "unprognostic (1.91e-2)" 19.1 17.0 15.8 18.5 16.7 9.5 19.6 21.7 17.4 25.1 17.2 22.2 14.2 24.8 19.4 18.6 21.8 12.2 15.6 16.1 17.6 18.8 15.3 15.2 25.1 16.5 15.7 28.5 20.5 20.3 21.8 18.7 15.2 21.4 16.3 23.1 20.4 14.6 19.6 21.9 21.6 17.7 15.7 25.7 19.2 25.8 16.9 26.2 20.7 14.6 25.0 20.8 19.6 17.4 39.5 34.2 47.4 49.0 22.2 23.3 37.8 26.7 24.0 42.5 34.7 47.8 30.6 64.3 44.0 26.0 36.1 51.2 39.6 33.5 36.5 39.1 19.9 38.7 33.4 40.7 23.5 53.4 36.1 16.8 43.8 22.5 20.4 22.2 30.6 33.1 36.3 50.9 33.9 50.9 74.2 41.3 43.2 33.3 41.8 55.6 31.4 28.0 25.1 44.3 42.5 38.5 42.8 51.7 37.3 26.9 41.1 62.3 28.7 44.6 33.8 27.1 42.2 32.9 50.5 43.2 31.1 31.1 29.1 3.9 9.5 13.4 13.4 10.3 15.4 13.1 14.3 13.6 9.8 17.7 13.3 12.4 7.0 8.8 10.7 21.6 10.0 7.1 15.8 16.7 21.7 17.4 16.1 17.6 16.5 15.7 15.2 15.7 16.9 17.4 7.3 9.6 12.6 24.2 12.5 6.4 3.1 6.7 10.8 13.2 9.7 8.0 5.2 10.0 7.3 9.2 22.9 11.2 11.8 8.2 0.0 8.9 7.5 6.9 11.7 9.1 9.5 9.7 29.4 12.4 8.8 7.9 12.2 7.7 1.3 11.6 9.3 9.3 7.8 3.3 31.6 10.4 4.1 10.1 3.2 5.0 13.7 6.7 3.6 42.2 9.2 7.4 13.4 19.6 35.8 11.7 3.2 15.4 12.1 4.4 4.5 5.2 8.6 9.0 6.6 10.7 7.0 28.1 15.7 8.7 5.4 6.7 8.7 8.4 9.2 3.6 NDRG1 "CAP43, DRG1, NDR1, RTP, TDD5" ENSG00000104419 "N-myc downstream regulated 1" Q92597 8 133237175-133302022 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cancer-related genes, Charcot-Marie-Tooth disease, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 613.9" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 571.9;Distal enterocytes: 405.4;Horizontal cells: 588.9;Suprabasal keratinocytes: 667.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTCEpi: 606.9;hTERT-HME1: 1226.9;U-87 MG: 772.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006881 Approved Supported Microtubules,Cytosol NA NA 200000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 27: Brain & Skin - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 28: Keratinocytes - Keratinization" Cytosol Microtubules "HPA006881: AB_1078392" "unprognostic (6.96e-3)" "unprognostic (3.31e-3)" "unprognostic (8.53e-2)" "unprognostic (1.41e-3)" "unprognostic (1.54e-3)" "unprognostic (2.60e-2)" "prognostic unfavorable (1.47e-4)" "unprognostic (3.04e-3)" "unprognostic (5.33e-2)" "unprognostic (4.29e-2)" "unprognostic (9.09e-2)" "unprognostic (2.46e-1)" "prognostic unfavorable (4.13e-4)" "unprognostic (7.27e-2)" "unprognostic (1.91e-1)" "unprognostic (2.47e-3)" "unprognostic (4.28e-2)" 161.2 72.9 299.1 55.9 523.6 130.0 107.6 413.5 300.2 169.4 132.8 130.0 242.2 92.9 34.3 343.1 106.4 87.8 99.8 254.5 316.6 192.4 49.6 116.6 38.7 523.2 500.0 126.1 52.8 69.1 82.2 110.8 476.8 354.3 77.8 86.0 130.8 60.0 28.2 262.6 258.1 61.9 333.7 39.4 154.0 28.1 423.1 55.1 80.5 44.6 88.1 105.5 273.8 613.9 191.6 24.0 1.7 0.8 116.3 86.8 26.0 13.7 103.0 9.8 52.5 12.5 27.6 1.5 133.0 58.0 21.9 62.4 1.7 316.8 18.0 13.3 226.8 1.9 55.6 14.7 46.3 7.0 4.6 79.2 606.9 51.2 1226.9 124.2 45.2 27.9 2.0 138.3 17.2 11.0 19.1 20.8 3.0 69.8 155.8 1.7 19.4 86.2 29.7 28.0 13.8 13.0 31.0 312.1 73.3 48.6 1.3 20.0 58.5 84.4 43.6 40.7 10.4 96.3 280.3 0.8 772.5 69.5 161.5 10.9 4.3 0.0 5.8 3.4 9.1 1.6 5.3 6.9 6.0 1.4 3.9 3.1 4.0 1.5 4.2 13.0 8.1 3.7 299.1 523.6 413.5 300.2 254.5 316.6 523.2 500.0 476.8 333.7 423.1 613.9 123.0 144.2 47.4 14.4 23.6 571.9 141.3 207.3 42.1 68.8 28.6 31.2 20.6 80.1 102.9 187.6 2.1 12.8 68.1 405.4 33.2 33.2 5.3 57.4 59.0 217.7 22.1 17.4 7.7 13.7 138.2 90.5 151.4 167.7 22.2 41.0 112.8 64.0 16.5 588.9 5.7 140.9 83.4 31.1 109.5 5.9 49.0 42.7 101.4 28.1 25.7 81.2 14.4 20.6 136.2 62.9 155.9 44.0 23.5 264.3 402.5 87.5 38.7 40.3 46.0 65.2 44.3 1.2 7.1 113.0 667.4 43.4 45.7 32.6 124.7 280.8 NDUFA10 CI-42k ENSG00000130414 "NADH:ubiquinone oxidoreductase subunit A10" O95299 2 239892450-240025743 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 332.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059529, HPA067045, CAB070846" Approved Supported Mitochondria "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB070846: AB_11152346, HPA059529: AB_2684051, HPA067045: AB_2732756" "unprognostic (2.12e-2)" "unprognostic (8.94e-3)" "unprognostic (8.73e-2)" "unprognostic (2.02e-2)" "unprognostic (8.96e-2)" "unprognostic (2.53e-1)" "unprognostic (8.78e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (2.95e-4)" "unprognostic (5.71e-2)" "unprognostic (2.47e-2)" "unprognostic (1.05e-1)" "prognostic favorable (2.09e-7)" "unprognostic (1.16e-1)" "unprognostic (4.96e-2)" "unprognostic (1.98e-1)" "unprognostic (2.95e-1)" 55.4 91.1 36.3 29.6 40.2 50.3 50.3 39.8 51.2 41.0 38.9 83.2 81.6 37.8 28.3 74.6 43.6 31.2 184.8 41.7 36.0 94.2 103.6 35.4 32.3 41.9 39.4 45.4 58.5 99.3 38.5 37.9 41.3 33.1 84.3 31.2 55.9 33.1 206.4 72.4 64.3 39.8 34.0 37.7 71.7 35.3 37.7 45.3 38.8 332.0 49.7 47.3 49.2 39.4 74.4 65.5 46.3 81.5 54.8 95.4 75.5 49.0 70.9 71.3 77.8 72.8 82.8 51.0 31.8 64.2 60.8 96.2 109.8 103.1 92.6 59.7 90.9 72.9 65.6 174.6 72.4 96.9 58.6 95.5 80.3 68.5 85.0 66.6 96.6 74.6 102.0 34.8 81.8 124.8 95.6 110.5 56.3 114.4 81.0 93.2 114.4 81.2 108.7 152.1 70.5 54.6 55.3 131.8 108.9 33.3 121.2 97.4 69.9 52.7 60.7 70.7 75.8 77.3 24.6 79.2 60.3 80.9 72.8 30.2 106.3 47.1 72.9 115.8 93.8 95.4 70.7 77.5 147.9 77.0 68.2 69.4 26.7 97.6 103.3 49.7 92.7 104.6 36.3 40.2 39.8 51.2 41.7 36.0 41.9 39.4 41.3 34.0 37.7 39.4 66.8 76.9 74.1 31.6 63.5 104.9 96.5 193.5 60.3 80.8 88.4 89.5 354.8 87.2 114.0 77.3 62.6 216.4 58.1 137.3 311.0 112.5 47.5 66.8 83.2 67.4 92.9 57.6 83.1 78.5 124.0 71.7 62.2 76.6 65.9 103.7 66.4 139.1 125.2 50.5 68.5 152.3 103.7 90.5 82.0 85.3 50.1 65.2 112.1 27.2 107.8 72.2 53.5 37.7 71.4 77.7 125.5 49.2 56.7 62.1 182.7 303.0 77.7 110.4 65.7 74.6 77.3 84.2 73.4 107.2 118.9 218.1 63.0 185.3 234.2 110.0 NDUFA3 B9 ENSG00000170906 "NADH:ubiquinone oxidoreductase subunit A3" O95167 19 54102728-54109257 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 625.9;skeletal muscle: 492.4" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1133.8;Late spermatids: 2033.9;Proximal tubular cells: 1213.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 74.0" "Low region specificity" "Detected in all" HPA046976 Supported NA NA "Cluster 11: Basophils - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" "HPA046976: AB_10960994" "unprognostic (3.04e-2)" "unprognostic (4.12e-3)" "unprognostic (9.53e-2)" "unprognostic (5.95e-2)" "unprognostic (6.73e-2)" "unprognostic (3.14e-2)" "unprognostic (3.91e-1)" "unprognostic (3.05e-1)" "unprognostic (2.95e-1)" "unprognostic (2.00e-2)" "prognostic favorable (9.65e-4)" "unprognostic (9.91e-2)" "unprognostic (3.24e-3)" "unprognostic (7.79e-2)" "unprognostic (1.33e-1)" "unprognostic (7.24e-2)" "prognostic favorable (4.80e-4)" 134.4 192.6 20.7 3.2 21.1 6.5 108.0 27.2 28.0 96.2 23.5 142.8 11.2 102.6 5.2 127.7 95.8 5.4 625.9 21.3 21.4 259.5 248.2 102.5 5.1 22.3 20.2 104.5 124.0 4.8 225.9 3.3 21.4 122.5 8.1 6.5 113.4 3.7 492.4 84.8 117.6 4.0 17.3 133.5 160.7 164.3 24.3 3.5 152.4 10.8 5.4 97.6 92.3 26.6 9.1 9.7 8.4 11.6 10.3 10.7 5.2 7.6 9.3 6.5 7.3 10.1 7.2 8.2 5.3 7.4 6.1 6.6 6.9 16.7 3.5 11.5 32.0 9.5 9.6 11.9 7.6 9.2 2.3 6.2 15.1 5.2 8.5 3.1 11.7 7.3 4.9 3.5 6.9 32.3 7.3 10.5 7.4 74.0 15.2 4.3 5.0 17.7 4.9 23.2 14.1 6.9 6.9 17.7 4.3 10.3 23.4 9.6 8.7 7.4 4.5 4.0 13.2 6.9 5.7 3.9 9.1 10.5 4.5 25.2 12.9 20.9 12.6 15.3 13.0 18.4 13.0 12.9 14.3 16.1 13.5 13.6 12.5 18.0 12.3 23.7 14.5 22.3 20.7 21.1 27.2 28.0 21.3 21.4 22.3 20.2 21.4 17.3 24.3 26.6 146.9 96.1 117.4 4.6 168.1 39.8 53.5 266.5 58.6 37.7 196.2 212.6 1133.8 203.0 171.4 393.6 10.4 164.1 158.3 544.0 815.9 183.6 497.6 239.6 124.9 118.2 300.5 169.0 5.2 192.5 171.9 122.9 174.8 180.2 116.5 138.3 194.9 527.7 306.9 23.5 6.4 380.2 209.5 267.4 114.4 2033.9 163.1 181.6 218.7 1.9 300.4 146.3 265.7 3.0 7.7 204.2 448.8 141.4 232.7 67.5 705.7 1213.0 225.1 71.0 85.5 62.5 125.8 215.3 69.8 122.6 62.5 148.4 168.6 75.3 404.2 66.6 NDUFAF7 "C2orf56, MidA, PRO1853" ENSG00000003509 "NADH:ubiquinone oxidoreductase complex assembly factor 7" Q7L592 2 37231631-37253403 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 38.8" "Group enriched" "Detected in all" 4 "Early spermatids: 196.6;Late spermatids: 109.6;Spermatocytes: 118.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045217 Uncertain NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 43: Testis - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA045217: AB_10960395" "unprognostic (6.38e-2)" "unprognostic (2.92e-2)" "unprognostic (2.13e-1)" "unprognostic (1.38e-2)" "unprognostic (1.17e-1)" "unprognostic (2.15e-1)" "prognostic unfavorable (1.48e-4)" "prognostic favorable (3.08e-4)" "unprognostic (5.44e-2)" "unprognostic (1.55e-2)" "unprognostic (9.88e-2)" "unprognostic (8.12e-3)" "unprognostic (5.94e-2)" "unprognostic (3.48e-2)" "unprognostic (1.03e-1)" "unprognostic (5.73e-2)" "unprognostic (8.67e-3)" 6.2 12.7 6.7 5.4 7.1 6.0 6.0 7.7 7.8 8.0 6.2 12.1 4.6 7.8 8.0 5.6 6.0 5.9 15.5 7.3 6.6 9.3 10.6 5.5 6.9 6.5 6.5 7.0 5.7 8.2 6.8 5.9 6.8 6.6 5.9 10.0 5.7 5.4 20.4 4.9 5.7 7.3 5.8 6.6 6.2 38.8 6.2 8.2 5.1 24.4 5.9 6.7 6.1 7.1 20.2 10.6 13.2 11.6 8.3 17.6 7.3 6.6 10.5 11.1 14.1 22.9 8.5 17.1 8.1 6.0 18.9 14.8 16.2 8.3 13.1 11.9 12.1 12.6 13.1 21.1 10.2 12.6 6.1 13.8 13.6 9.1 5.6 11.8 17.4 6.4 15.5 11.1 6.7 7.4 12.6 13.5 17.3 15.9 9.5 11.3 10.2 14.4 15.4 7.4 13.7 11.0 8.2 13.9 14.3 18.6 8.4 4.9 3.4 9.2 12.3 11.6 12.1 9.7 6.0 19.8 13.4 16.9 7.9 3.0 4.3 2.6 4.1 3.7 1.8 4.7 3.6 3.5 5.3 4.1 3.5 3.1 2.7 4.1 2.7 4.2 4.6 2.0 6.7 7.1 7.7 7.8 7.3 6.6 6.5 6.5 6.8 5.8 6.2 7.1 10.9 9.6 10.0 12.7 15.5 4.8 9.5 12.3 11.4 18.1 6.4 5.6 13.4 2.8 8.4 11.0 22.9 15.0 16.1 3.7 17.6 10.5 196.6 6.6 12.1 9.4 2.4 6.5 30.5 6.3 10.8 9.7 8.6 7.2 7.6 11.9 7.5 5.6 9.4 11.8 26.9 5.5 12.2 7.3 7.8 109.6 13.4 9.4 3.6 15.0 10.5 7.6 10.3 13.6 15.4 8.8 2.0 16.6 9.3 5.9 7.7 14.8 11.3 21.8 6.6 10.1 18.0 118.4 14.4 7.4 4.0 11.5 13.6 16.1 6.2 6.3 NDUFB3 B12 ENSG00000119013 "NADH:ubiquinone oxidoreductase subunit B3" O43676 2 201071433-201085750 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 704.3;tongue: 727.7" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1711.2;Distal tubular cells: 1064.4;Proximal tubular cells: 780.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034596 Enhanced NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "HPA034596: AB_10602712" "unprognostic (5.38e-2)" "unprognostic (2.90e-1)" "unprognostic (4.46e-2)" "unprognostic (6.85e-2)" "unprognostic (1.85e-1)" "prognostic unfavorable (7.24e-4)" "unprognostic (1.41e-3)" "unprognostic (6.29e-2)" "unprognostic (8.81e-3)" "unprognostic (2.55e-2)" "unprognostic (1.53e-1)" "unprognostic (1.20e-1)" "unprognostic (1.37e-2)" "unprognostic (9.40e-3)" "unprognostic (9.20e-2)" "unprognostic (1.94e-1)" "unprognostic (7.27e-2)" 119.4 114.4 151.2 88.9 152.7 79.7 105.5 165.7 227.5 69.9 161.9 185.7 136.7 46.4 132.2 98.4 66.1 66.3 389.3 151.5 165.1 247.1 195.3 63.5 103.7 158.2 155.4 46.2 54.7 219.3 57.8 78.0 158.1 77.1 174.6 140.8 100.8 75.8 704.3 52.0 127.9 73.8 157.2 61.6 115.5 83.1 158.2 143.4 96.0 727.7 128.8 95.4 53.7 160.6 180.1 148.9 227.5 122.0 226.3 207.0 183.1 224.8 160.1 171.9 200.3 347.2 211.3 144.4 249.8 211.4 261.9 154.5 209.6 287.7 269.4 294.5 460.6 349.0 363.8 394.8 141.2 500.9 170.5 180.1 223.6 203.3 119.2 211.3 250.3 259.2 311.1 240.3 313.1 234.4 313.8 459.8 129.9 392.4 536.7 215.6 200.4 388.0 380.6 278.7 209.5 150.1 176.0 153.2 258.2 353.2 150.7 373.0 227.3 144.8 179.7 150.9 222.8 174.5 435.3 452.6 246.0 284.4 172.6 205.2 135.4 159.4 116.1 205.3 129.2 148.8 132.7 135.7 177.3 117.3 115.2 140.9 267.3 141.6 213.3 211.8 183.1 109.6 151.2 152.7 165.7 227.5 151.5 165.1 158.2 155.4 158.1 157.2 158.2 160.6 95.3 80.1 57.7 18.9 100.9 78.1 100.0 433.7 66.6 52.9 101.7 128.1 1711.2 141.5 205.1 187.6 12.5 254.6 83.5 473.9 1064.4 247.0 218.1 191.6 93.9 101.9 146.4 113.8 13.2 201.7 208.9 103.4 118.7 135.2 78.0 61.0 86.7 260.5 288.2 32.0 14.7 299.0 248.2 121.6 107.1 59.9 95.4 126.8 168.9 10.3 292.9 184.6 116.4 7.5 19.9 177.3 411.0 101.5 135.2 72.5 496.3 780.3 229.2 92.0 92.1 82.3 125.4 270.0 89.7 169.2 91.9 157.6 89.7 113.9 322.1 132.9 NDUFB4 B15 ENSG00000065518 "NADH:ubiquinone oxidoreductase subunit B4" O95168 3 120596328-120602507 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 945.3" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1493.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051739, HPA064441" Enhanced Supported "Nucleoplasm,Nuclear membrane,Mitochondria" No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "Nucleoplasm, Nuclear membrane" "HPA051739: AB_2681585, HPA064441: " "unprognostic (1.75e-1)" "unprognostic (2.57e-3)" "unprognostic (6.95e-2)" "unprognostic (4.69e-2)" "unprognostic (1.59e-1)" "unprognostic (1.31e-1)" "unprognostic (1.72e-2)" "unprognostic (1.62e-2)" "unprognostic (1.47e-1)" "unprognostic (4.35e-3)" "unprognostic (9.66e-3)" "unprognostic (7.97e-2)" "unprognostic (2.84e-1)" "unprognostic (3.69e-2)" "unprognostic (1.01e-1)" "unprognostic (1.12e-1)" "prognostic favorable (1.79e-4)" 148.6 338.4 159.7 90.3 169.1 112.4 145.1 175.9 203.2 126.2 173.2 170.0 147.8 117.9 133.8 159.5 113.0 85.7 619.5 163.5 178.4 232.4 187.4 102.9 93.8 168.3 163.0 119.8 137.4 260.3 170.2 76.8 168.6 118.1 148.7 100.2 148.4 117.4 945.3 144.5 135.6 103.4 170.7 112.1 162.3 106.5 161.7 125.6 113.1 562.2 114.2 133.5 142.1 172.8 294.8 204.3 246.7 248.5 151.0 181.4 199.2 157.0 212.1 205.4 224.5 200.9 219.8 147.8 311.6 177.8 255.6 272.5 191.3 202.7 155.7 227.5 212.6 226.1 205.7 208.1 90.4 202.7 256.8 161.3 268.5 98.9 125.8 246.0 258.5 271.7 138.5 219.2 220.9 224.1 398.6 294.8 193.9 478.9 554.7 228.8 141.0 325.8 337.3 177.9 273.8 283.4 186.5 205.7 360.0 162.0 348.0 319.9 199.8 179.0 233.2 76.9 226.5 263.2 260.1 454.3 283.6 279.8 250.8 205.0 164.8 197.2 156.0 229.5 162.2 231.6 215.2 176.8 213.9 176.3 182.2 181.8 101.6 152.7 238.2 267.9 300.6 205.7 159.7 169.1 175.9 203.2 163.5 178.4 168.3 163.0 168.6 170.7 161.7 172.8 274.1 163.5 162.6 36.9 167.0 222.3 289.0 612.6 190.6 137.8 290.1 351.3 1493.1 311.7 348.3 320.0 58.4 366.0 158.1 472.4 1226.7 556.7 999.2 259.9 188.9 235.7 298.7 196.9 22.6 620.9 421.0 213.7 175.3 293.5 174.8 139.4 183.5 513.9 330.3 84.1 22.0 526.3 451.6 240.2 247.9 164.6 275.2 196.2 434.0 15.9 339.2 340.7 186.4 13.0 31.2 567.9 581.8 277.2 283.2 243.2 613.4 1225.1 266.2 168.4 256.4 208.1 259.0 418.9 87.5 288.4 251.5 352.4 168.1 271.3 462.8 344.0 NDUFS8 "CI-23k, TYKY" ENSG00000110717 "NADH:ubiquinone oxidoreductase core subunit S8" O00217 11 68030617-68036644 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Oxidoreductase, Translocase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 833.5;Late spermatids: 797.2;Proximal tubular cells: 927.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018524, HPA067429" Enhanced Approved Mitochondria "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA018524: AB_1854355, HPA067429: " "unprognostic (2.90e-1)" "unprognostic (1.41e-3)" "unprognostic (2.41e-1)" "unprognostic (5.20e-2)" "unprognostic (1.37e-1)" "unprognostic (1.30e-3)" "unprognostic (1.36e-1)" "unprognostic (7.75e-2)" "unprognostic (3.15e-1)" "unprognostic (1.77e-2)" "unprognostic (3.81e-2)" "unprognostic (1.81e-1)" "prognostic favorable (3.27e-8)" "unprognostic (2.29e-1)" "unprognostic (1.38e-1)" "unprognostic (2.60e-2)" "unprognostic (9.45e-2)" 99.2 308.4 141.2 38.8 153.2 56.2 87.7 157.2 180.4 73.2 172.3 142.0 81.4 89.2 27.2 115.3 81.3 29.1 468.2 144.2 152.0 188.6 152.0 73.1 42.2 149.6 144.9 68.2 97.7 74.6 130.6 33.6 145.8 118.2 36.7 49.5 96.2 66.7 406.4 93.0 84.4 39.0 142.2 76.9 137.8 104.7 154.0 40.3 101.8 275.5 30.1 94.4 76.0 150.2 152.9 366.4 94.6 137.0 70.9 63.5 132.4 102.3 88.5 155.6 118.9 338.4 159.6 118.4 186.8 85.9 134.6 181.2 108.8 128.4 53.1 139.4 264.9 107.2 217.1 186.3 171.8 99.1 112.1 80.5 126.5 111.1 124.8 82.0 106.2 159.9 110.3 121.1 99.2 358.6 219.2 216.9 125.2 377.7 308.0 154.4 95.9 384.9 192.8 123.3 125.5 102.2 75.7 171.7 392.3 66.5 245.6 105.9 84.1 155.6 133.9 224.8 148.8 165.2 188.5 99.7 252.3 121.8 111.2 84.7 220.1 124.0 182.4 232.0 170.1 183.3 154.6 165.5 309.4 156.3 146.2 164.2 20.7 309.6 131.7 324.3 202.2 232.4 141.2 153.2 157.2 180.4 144.2 152.0 149.6 144.9 145.8 142.2 154.0 150.2 88.7 89.8 90.1 18.6 92.3 85.4 95.5 284.3 104.7 83.4 147.2 156.7 301.9 143.0 164.9 213.3 54.2 279.6 97.8 301.0 833.5 200.8 225.7 101.1 74.8 85.3 205.0 149.8 13.6 199.3 165.9 109.6 147.3 79.7 95.8 156.5 73.5 231.7 276.6 50.5 19.3 277.2 240.1 124.1 108.0 797.2 100.6 128.7 163.7 13.1 187.4 143.6 128.8 12.1 15.4 173.7 194.9 108.0 157.8 118.6 337.1 927.8 120.8 118.7 59.2 81.2 208.6 105.9 72.7 209.7 116.2 172.4 102.7 278.7 318.2 139.1 NECTIN2 "CD112, HVEB, PRR2, PVRL2, PVRR2" ENSG00000130202 "Nectin cell adhesion molecule 2" Q92692 19 44846175-44889223 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 136.6;Ductal cells: 215.6;Exocrine glandular cells: 154.2;Glandular and luminal cells: 126.1;Pancreatic endocrine cells: 241.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 10.4" "Lineage enhanced" "Detected in many" "granulocytes: 10.4" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012759, CAB026138, HPA073459" Enhanced Approved "Nucleoli fibrillar center,Cell Junctions" NA Yes 5900000 "Cluster 52: Eosinophils - Transcription" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 39: CACO-2 - Unknown function" "Cluster 7: Non-specific - Mitochondria" "Nucleoli fibrillar center, Cell Junctions" "CAB026138: , HPA012759: AB_1846227, HPA073459: " "unprognostic (3.30e-2)" "unprognostic (2.84e-1)" "unprognostic (1.07e-1)" "unprognostic (5.61e-3)" "unprognostic (7.45e-2)" "unprognostic (2.21e-1)" "unprognostic (1.66e-2)" "unprognostic (6.63e-2)" "unprognostic (2.85e-1)" "unprognostic (2.97e-1)" "unprognostic (6.93e-2)" "unprognostic (3.19e-1)" "unprognostic (1.60e-1)" "unprognostic (2.15e-1)" "unprognostic (1.61e-1)" "unprognostic (8.19e-2)" "unprognostic (2.05e-1)" 71.4 79.1 30.8 32.1 28.4 15.8 66.0 29.8 34.3 41.7 44.3 42.3 55.3 45.0 58.2 76.3 43.9 52.5 71.3 29.2 33.1 79.6 118.5 72.9 15.8 35.8 33.0 41.7 55.0 61.5 39.1 77.2 32.9 69.2 32.8 16.7 62.6 30.4 20.1 52.5 47.5 31.3 31.8 58.1 75.4 65.8 34.7 6.9 57.4 17.7 25.3 55.8 49.3 28.9 73.8 89.3 118.3 140.6 59.3 35.8 123.7 62.6 83.9 120.4 136.6 194.8 171.0 0.6 79.2 79.0 61.1 98.5 106.6 55.6 91.7 3.2 53.2 43.0 30.8 128.6 145.0 0.7 117.9 64.9 22.5 56.2 44.8 123.2 149.3 3.0 71.1 0.7 59.2 146.4 0.6 5.6 92.8 249.8 27.7 4.3 37.7 3.2 139.5 100.1 5.4 15.2 74.9 127.0 28.7 210.4 97.2 47.1 140.1 31.3 105.5 23.7 48.6 9.0 25.8 0.6 57.3 10.0 83.0 1.8 2.0 10.4 0.0 0.7 0.2 0.0 0.0 0.0 2.7 0.0 0.0 0.0 1.8 0.0 0.4 0.3 0.0 0.7 30.8 28.4 29.8 34.3 29.2 33.1 35.8 33.0 32.9 31.8 34.7 28.9 136.6 35.3 31.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 108.4 54.9 0.0 0.0 6.8 58.8 0.0 109.3 2.6 0.0 3.9 215.6 0.0 73.8 66.3 58.8 0.0 0.0 0.0 154.2 97.8 30.4 0.0 126.1 3.8 75.0 0.0 0.0 54.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.2 0.0 0.0 80.1 0.0 0.0 0.0 0.0 241.8 0.0 0.0 0.1 0.0 0.0 27.1 3.6 0.0 0.0 0.0 42.9 0.0 0.0 0.0 0.0 101.8 2.2 58.3 0.0 0.0 NEDD1 "GCP-WD, TUBGCP7" ENSG00000139350 "NEDD1 gamma-tubulin ring complex targeting factor" Q8NHV4 12 96907224-96953780 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 255.8;Late spermatids: 92.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ: 133.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038591 Approved Approved Nucleoplasm,Centrosome NA NA "Cluster 15: NK-cells - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nucleoplasm, Centrosome" "HPA038591: AB_10674688" "unprognostic (7.93e-2)" "unprognostic (3.18e-1)" "unprognostic (7.00e-2)" "unprognostic (1.19e-2)" "unprognostic (2.21e-1)" "unprognostic (5.92e-2)" "prognostic unfavorable (1.94e-4)" "prognostic unfavorable (3.70e-4)" "unprognostic (1.81e-2)" "unprognostic (9.29e-2)" "unprognostic (1.83e-2)" "unprognostic (1.56e-1)" "unprognostic (2.46e-3)" "unprognostic (7.29e-2)" "unprognostic (2.28e-1)" "unprognostic (1.34e-1)" "unprognostic (5.59e-2)" 9.1 5.8 3.4 9.7 4.3 15.2 12.8 4.0 3.9 9.9 7.7 8.3 7.1 12.7 6.4 10.0 9.1 7.5 9.2 3.1 4.7 8.9 6.3 8.8 15.4 5.0 4.5 9.8 7.1 14.9 3.8 11.0 4.7 10.6 9.7 7.2 6.8 8.2 38.0 8.2 6.9 13.1 4.8 13.4 7.2 23.6 3.7 22.5 10.5 25.6 15.2 9.6 6.1 6.3 39.4 25.8 43.3 26.8 21.1 19.0 30.7 133.1 47.0 60.5 51.7 17.0 14.2 24.1 12.6 107.7 28.8 34.5 29.5 31.0 80.7 46.7 26.2 30.2 16.1 15.1 17.5 41.8 26.2 14.1 24.9 37.2 28.3 39.8 30.0 41.0 17.8 17.3 43.9 16.3 76.1 19.0 23.8 20.6 80.8 40.0 43.7 24.0 25.0 25.7 13.4 23.6 37.4 20.9 23.7 33.5 28.2 14.6 21.5 38.0 28.8 27.2 31.9 17.0 22.0 32.3 11.7 20.9 46.7 14.1 8.5 25.6 13.8 13.8 15.8 11.1 15.4 15.0 7.4 10.4 15.7 12.5 6.3 19.9 10.2 5.7 17.8 9.4 3.4 4.3 4.0 3.9 3.1 4.7 5.0 4.5 4.7 4.8 3.7 6.3 18.8 9.6 11.5 11.4 19.1 19.4 28.1 7.3 13.1 8.0 10.4 6.9 10.5 21.5 11.9 16.5 0.0 8.2 20.5 6.3 9.8 9.8 255.8 15.3 10.0 14.6 6.1 34.1 3.7 8.2 13.9 13.3 8.6 9.7 16.5 9.3 15.0 4.8 8.6 18.5 3.0 7.5 4.1 8.1 9.2 92.0 12.5 9.4 7.2 15.9 7.5 11.5 17.5 9.0 15.1 8.3 8.3 10.1 13.3 49.6 4.7 11.2 21.8 8.4 19.7 13.9 13.6 34.3 26.0 12.0 14.1 4.0 24.6 9.8 8.0 18.3 NEK10 FLJ32685 ENSG00000163491 "NIMA related kinase 10" Q6ZWH5 3 27110085-27369460 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Ciliopathy, Disease variant, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 36.6;tongue: 20.0" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 87.6;Early spermatids: 123.5;Endometrial ciliated cells: 59.3;Excitatory neurons: 131.4;Inhibitory neurons: 130.2;Late spermatids: 61.7;Respiratory ciliated cells: 104.2" "Cancer enriched" "Detected in single" 5 "breast cancer: 1.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 6.0;LHCN-M2: 8.2;U-2 OS: 6.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA038941 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 49: Ciliated cells - Cilium organization" Vesicles Nucleoplasm "HPA038941: AB_10673600" "prognostic favorable (4.20e-4)" "unprognostic (2.17e-1)" "unprognostic (8.78e-2)" "unprognostic (2.15e-2)" "unprognostic (3.37e-2)" "unprognostic (3.02e-1)" "unprognostic (1.12e-1)" "unprognostic (1.83e-1)" "unprognostic (1.26e-1)" "unprognostic (1.93e-2)" "unprognostic (2.20e-3)" "unprognostic (1.37e-1)" "unprognostic (7.67e-2)" "unprognostic (1.33e-2)" "unprognostic (1.38e-2)" "unprognostic (1.57e-3)" "unprognostic (2.14e-1)" 0.2 0.3 3.0 0.3 5.3 0.3 14.0 0.0 9.4 1.4 3.3 2.0 2.5 0.8 8.3 1.8 11.0 1.4 3.3 9.6 5.0 1.7 2.5 2.4 0.5 3.3 5.7 0.7 0.7 0.4 3.4 0.1 2.7 1.7 0.5 6.2 0.3 1.2 12.4 0.3 0.8 0.3 2.3 0.4 1.0 36.6 6.1 0.5 0.7 20.0 0.6 1.2 0.2 0.9 0.8 1.6 0.8 0.9 0.6 1.5 0.3 6.0 0.9 1.6 1.4 0.0 0.4 0.5 1.4 2.5 1.1 0.1 0.4 0.4 1.7 1.1 0.6 0.1 3.4 2.9 0.1 0.3 0.8 1.8 0.4 2.5 0.1 2.0 1.1 3.4 0.1 0.6 8.2 0.1 0.6 0.4 0.5 0.2 0.2 0.8 0.3 0.2 3.0 0.5 0.1 0.2 0.9 0.3 0.4 0.5 4.8 0.3 0.7 4.3 6.8 0.2 0.6 0.2 0.2 0.4 3.6 0.7 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.0 5.3 0.0 9.4 9.6 5.0 3.3 5.7 2.7 2.3 6.1 0.9 1.5 6.4 0.0 11.4 0.3 0.3 0.3 3.2 0.0 14.5 25.8 7.4 12.9 4.3 9.3 1.8 87.6 0.0 0.8 0.2 0.0 0.4 123.5 59.3 1.3 2.4 0.0 0.0 131.4 0.0 0.3 3.1 0.0 7.7 0.0 1.1 0.7 1.3 0.2 0.0 130.2 0.4 12.2 1.0 0.8 61.7 1.8 1.1 0.0 32.8 0.1 1.0 1.0 20.6 12.9 0.2 2.7 1.2 0.1 1.9 2.1 0.3 104.2 19.1 0.0 14.9 2.4 32.2 2.2 0.1 0.4 0.0 1.1 3.7 0.6 0.4 NEK5 ENSG00000197168 "NIMA related kinase 5" Q6P3R8 13 52033611-52129092 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 5.1;choroid plexus: 7.4;fallopian tube: 8.8;testis: 10.8" "Group enriched" "Detected in many" 4 "Early spermatids: 57.9;Endometrial ciliated cells: 75.8;Late spermatids: 32.0;Respiratory ciliated cells: 98.6;Spermatocytes: 32.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "JURKAT: 1.2;OE19: 2.4;T-47d: 1.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA035565, HPA041399" Enhanced NA NA "Cluster 11: Basophils - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 21: OE19 - Mitochondria" "Cluster 49: Ciliated cells - Cilium organization" "HPA035565: AB_10672095, HPA041399: AB_2677453" "unprognostic (4.14e-2)" "unprognostic (1.49e-1)" "unprognostic (1.89e-1)" "unprognostic (5.80e-3)" "unprognostic (2.80e-2)" "unprognostic (2.47e-1)" "unprognostic (3.57e-2)" "unprognostic (6.50e-2)" "unprognostic (8.82e-2)" "unprognostic (1.32e-1)" "unprognostic (1.37e-2)" "unprognostic (2.94e-1)" "unprognostic (2.06e-3)" "unprognostic (1.83e-3)" "unprognostic (1.10e-1)" "unprognostic (1.19e-3)" "unprognostic (9.44e-3)" 0.1 0.1 1.1 0.2 1.5 0.3 0.4 0.7 0.7 0.3 7.4 0.1 0.1 0.5 0.3 0.0 8.8 0.1 0.4 1.5 1.7 0.4 0.0 1.3 0.1 5.1 5.1 0.1 0.1 0.7 0.1 0.4 2.5 0.5 0.2 1.6 0.1 0.1 0.3 0.2 0.1 0.2 3.6 0.2 0.1 10.8 2.6 0.3 0.3 0.1 0.1 0.1 0.0 2.7 0.1 0.1 0.1 0.6 0.0 0.2 0.8 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.4 0.1 0.1 0.4 0.6 0.1 0.2 0.0 0.1 0.1 0.0 1.2 0.4 0.2 0.0 0.5 0.1 0.3 0.2 2.4 0.2 0.0 0.0 0.0 0.6 0.1 0.1 0.3 0.2 0.0 0.2 0.3 1.1 0.4 0.2 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 1.1 1.5 0.7 0.7 1.5 1.7 5.1 5.1 2.5 3.6 2.6 2.7 1.4 0.0 2.0 2.6 1.5 0.0 1.9 0.3 0.0 9.2 3.0 1.8 2.0 2.8 12.1 7.3 14.6 2.6 2.5 0.5 1.9 1.3 57.9 75.8 1.9 3.0 1.8 0.8 3.8 2.9 2.4 1.6 0.0 2.8 2.5 1.2 0.4 1.2 1.2 13.5 3.1 0.4 2.0 0.3 0.4 32.0 2.1 0.6 0.0 4.7 1.4 2.1 3.1 1.0 6.6 0.8 0.7 2.2 0.5 3.7 1.3 1.5 98.6 13.2 6.6 4.6 1.3 32.2 12.9 0.3 0.1 1.9 1.0 1.2 1.1 1.3 NELL2 NRP2 ENSG00000184613 "Neural EGFL like 2" Q99435 12 44508275-44921848 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 105.5;choroid plexus: 59.5;fallopian tube: 60.1;retina: 85.2" "Cell type enriched" "Detected in many" 6 "Excitatory neurons: 652.4" "Cancer enhanced" "Detected in many" "thyroid cancer: 33.3" "Group enriched" "Detected in many" 15 "amygdala: 48.9;basal ganglia: 60.0;cerebral cortex: 105.5;hippocampal formation: 89.6;white matter: 42.0" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 70.4;naive CD8 T-cell: 111.1" "Lineage enriched" "Detected in many" 10 "T-cells: 111.1" "Cell line enhanced" "Detected in some" "AF22: 104.6;HEK 293: 27.5;NTERA-2: 41.2;SCLC-21H: 75.6;U-266/70: 27.5;U-266/84: 29.5;U-698: 40.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035714, HPA035715" Uncertain Approved Vesicles "Secreted to blood" NA NA 6400000 "Cluster 32: T-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA035714: AB_2674746, HPA035715: AB_10669602" "unprognostic (4.25e-3)" "unprognostic (4.27e-2)" "unprognostic (1.06e-1)" "unprognostic (3.10e-2)" "unprognostic (3.01e-2)" "unprognostic (7.18e-2)" "unprognostic (5.85e-2)" "unprognostic (2.59e-2)" "unprognostic (4.85e-2)" "unprognostic (2.80e-1)" "prognostic favorable (5.56e-4)" "unprognostic (1.19e-1)" "unprognostic (1.71e-5)" "unprognostic (8.45e-2)" "unprognostic (2.92e-1)" "unprognostic (3.60e-3)" "unprognostic (3.75e-2)" 4.6 16.9 48.9 10.9 60.0 7.3 1.9 1.3 105.5 23.1 59.5 2.0 26.3 2.2 0.4 1.2 60.1 1.9 0.4 89.6 4.5 1.2 1.0 5.0 20.7 0.0 0.0 0.8 0.9 0.2 34.6 0.3 0.0 27.2 2.1 85.2 1.4 2.0 0.3 13.4 15.3 2.8 0.0 6.2 2.9 3.0 0.8 8.7 6.5 0.6 15.7 4.1 4.2 42.0 0.3 0.1 104.6 3.5 0.2 0.0 0.5 0.0 0.1 0.0 0.0 0.4 0.0 8.3 12.4 0.0 0.0 0.2 25.3 0.2 0.0 0.0 27.5 0.4 8.7 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.1 0.1 1.6 0.2 0.4 0.0 0.4 0.2 0.4 41.2 0.0 14.0 0.2 12.7 0.2 0.0 0.0 75.6 1.8 0.0 0.4 0.0 1.3 0.1 0.7 0.0 0.4 3.8 0.1 2.1 27.5 29.5 40.3 0.2 0.2 0.4 0.2 0.2 0.0 5.0 0.1 24.9 0.2 30.3 52.9 0.1 0.1 70.4 111.1 0.5 11.0 0.1 0.1 0.4 26.7 48.9 60.0 1.3 105.5 89.6 4.5 0.0 0.0 0.0 0.0 0.8 42.0 0.3 0.0 1.3 48.0 1.0 1.1 0.0 0.0 5.7 35.4 0.4 0.6 0.5 2.8 6.2 0.0 33.3 0.1 2.5 5.8 0.0 0.0 0.4 0.7 0.8 0.7 0.0 0.0 652.4 0.2 0.3 3.7 0.0 0.3 0.0 49.4 0.0 0.0 0.1 1.7 108.4 0.9 0.0 0.0 1.5 1.0 0.0 0.4 0.0 18.7 1.3 7.9 1.0 74.4 16.5 0.4 0.4 0.4 0.5 0.3 18.5 0.2 21.9 58.3 0.0 4.1 4.6 1.9 4.2 0.2 1.1 0.1 23.4 0.1 2.9 0.1 NETO1 "BCTL1, BTCL1" ENSG00000166342 "Neuropilin and tolloid like 1" Q8TDF5 18 72742314-72868146 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 21.9;retina: 34.6" "Group enriched" "Detected in some" 14 "Bipolar cells: 206.4;Excitatory neurons: 307.1;Inhibitory neurons: 345.9;Oligodendrocyte precursor cells: 172.4" "Cancer enhanced" "Detected in some" "glioma: 1.2" "Group enriched" "Detected in many" 41 "amygdala: 6.6;basal ganglia: 12.4;cerebral cortex: 21.9;hippocampal formation: 17.5;white matter: 16.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MOLT-4: 21.9;REH: 20.6;RPMI-8226: 32.7;RT4: 24.7;SCLC-21H: 26.9;U-2 OS: 11.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA064630 Approved "Golgi apparatus" "Secreted in brain" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 58: Brain - Synaptic function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" "HPA064630: AB_2685305" "unprognostic (4.02e-2)" "unprognostic (4.08e-3)" "unprognostic (2.75e-1)" "unprognostic (1.55e-2)" "unprognostic (6.04e-2)" "unprognostic (1.35e-5)" "unprognostic (4.05e-1)" "unprognostic (4.73e-2)" "unprognostic (3.09e-1)" "unprognostic (1.56e-1)" "unprognostic (6.63e-2)" "unprognostic (1.20e-1)" "unprognostic (1.73e-2)" "unprognostic (3.70e-2)" "unprognostic (3.35e-2)" "unprognostic (1.59e-1)" "unprognostic (9.13e-3)" 1.2 0.0 6.6 0.3 12.4 0.1 1.0 0.0 21.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.7 17.5 0.0 0.1 0.0 0.0 1.0 0.3 0.0 0.0 0.2 0.1 0.2 0.0 0.3 0.0 0.1 34.6 0.2 0.0 0.0 0.3 0.5 0.0 0.0 3.1 0.2 0.8 0.2 0.4 0.6 0.0 1.2 0.1 0.0 16.3 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.9 0.0 8.7 0.0 0.0 20.6 0.0 32.7 4.0 24.7 26.9 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 11.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 12.4 0.0 21.9 17.5 0.0 0.3 0.0 0.3 0.0 0.2 16.3 2.0 0.0 0.0 16.6 6.1 0.0 0.0 0.0 0.0 206.4 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 307.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 345.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 17.8 0.0 2.2 0.0 172.4 10.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.3 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NEURL1 "h-neu, neu-1, NEURL, RNF67" ENSG00000107954 "Neuralized E3 ubiquitin protein ligase 1" O76050 10 103493979-103592552 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Notch signaling pathway, Translation regulation, Ubl conjugation pathway" Transferase "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 146.9;tongue: 60.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 93.8;Early spermatids: 128.7;Intestinal goblet cells: 105.4;Late spermatids: 461.2;Paneth cells: 183.4;Syncytiotrophoblasts: 113.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 13 "intermediate monocyte: 45.1;non-classical monocyte: 112.0" "Lineage enriched" "Detected in many" 19 "monocytes: 112.0" "Cell line enhanced" "Detected in some" "BEWO: 13.7;HeLa: 8.6;HMC-1: 6.9;JURKAT: 7.4;SCLC-21H: 17.1;SiHa: 8.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044204 Enhanced NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" "HPA044204: AB_10959383" "unprognostic (1.21e-2)" "unprognostic (8.14e-2)" "unprognostic (1.18e-3)" "unprognostic (1.58e-4)" "unprognostic (1.31e-2)" "unprognostic (2.60e-1)" "unprognostic (5.24e-2)" "unprognostic (2.54e-1)" "unprognostic (1.37e-1)" "unprognostic (4.31e-2)" "unprognostic (1.32e-3)" "unprognostic (1.08e-1)" "unprognostic (8.61e-3)" "unprognostic (1.59e-1)" "unprognostic (1.44e-1)" "unprognostic (2.91e-4)" "unprognostic (3.23e-1)" 0.5 4.6 25.5 3.8 29.6 2.2 0.4 20.8 37.4 14.1 0.0 15.2 10.9 25.8 15.1 4.3 2.6 1.9 0.5 32.2 7.2 2.4 1.2 0.9 0.8 1.7 4.1 1.9 18.8 8.3 15.9 4.6 1.3 1.4 10.3 39.5 2.9 1.3 146.9 1.8 17.2 5.2 0.0 1.9 5.2 13.0 5.0 1.1 0.5 60.5 0.5 18.7 2.6 17.2 0.9 0.2 1.3 0.0 0.2 0.1 13.7 0.5 0.9 0.2 0.1 0.3 0.2 0.4 0.7 0.1 0.9 0.6 0.4 0.2 0.1 0.4 0.8 0.2 8.6 0.3 0.0 0.3 6.9 0.2 0.5 0.1 0.7 0.2 0.0 7.4 2.3 0.5 0.2 1.2 1.4 0.9 0.0 0.5 4.2 0.2 0.7 1.5 0.0 0.5 17.1 5.9 8.8 0.0 0.4 2.5 0.7 1.7 0.0 0.1 0.9 0.3 0.2 1.0 0.2 0.3 0.5 0.0 0.4 0.8 2.8 0.5 0.7 45.1 1.1 1.1 1.0 1.1 5.8 0.7 1.2 0.8 2.3 0.6 112.0 4.7 0.4 4.1 25.5 29.6 20.8 37.4 32.2 7.2 1.7 4.1 1.3 0.0 5.0 17.2 0.3 0.0 0.6 1.3 1.5 0.5 1.5 0.2 0.0 53.2 2.0 2.7 1.6 0.0 0.2 0.0 93.8 4.6 3.1 7.9 0.0 12.0 128.7 0.0 0.8 2.2 78.3 4.6 47.9 0.7 12.9 2.2 13.3 0.1 0.0 1.2 0.0 0.2 4.5 3.3 32.9 105.4 32.6 4.6 2.4 461.2 5.6 4.8 0.0 0.0 5.5 9.0 2.1 1.0 4.2 0.5 183.4 5.3 0.6 1.3 7.2 0.0 0.2 88.0 6.6 2.4 1.0 56.6 33.6 0.0 1.8 113.4 1.7 8.4 9.4 0.7 NFU1 "CGI-33, HIRIP5, NifU, NIFUC" ENSG00000169599 "NFU1 iron-sulfur cluster scaffold" Q9UMS0 2 69396113-69437628 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 189.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035826 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 38: Heart - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Cytosol Nucleoplasm "HPA035826: AB_2674803" "unprognostic (4.49e-3)" "unprognostic (5.62e-2)" "unprognostic (5.40e-2)" "unprognostic (1.84e-1)" "unprognostic (2.81e-1)" "unprognostic (2.16e-3)" "unprognostic (2.63e-2)" "unprognostic (1.76e-1)" "unprognostic (6.12e-2)" "unprognostic (1.55e-1)" "unprognostic (1.31e-1)" "unprognostic (2.12e-1)" "unprognostic (2.21e-3)" "unprognostic (2.63e-1)" "unprognostic (1.14e-1)" "unprognostic (1.91e-2)" "unprognostic (2.87e-1)" 66.8 46.3 36.8 22.5 39.3 33.4 56.8 40.0 56.0 35.6 37.4 51.4 31.3 35.9 51.9 27.9 35.3 29.0 110.4 37.5 40.9 64.2 39.5 31.8 30.0 40.2 39.7 38.0 39.9 43.3 45.1 38.1 41.4 34.3 38.1 56.9 41.2 36.5 140.8 22.3 33.4 33.1 39.9 31.0 43.8 34.6 39.0 22.8 41.9 120.2 29.5 44.8 31.1 42.0 59.3 59.2 56.1 55.5 70.4 75.4 61.6 61.0 62.0 59.0 47.8 114.7 56.9 42.4 30.0 57.0 85.6 25.4 63.7 64.2 79.5 77.8 62.3 43.5 38.2 102.0 70.1 73.7 59.2 58.4 37.2 67.5 41.2 56.0 65.6 41.8 80.1 41.8 99.1 11.9 39.1 119.0 53.9 62.9 64.3 42.6 85.5 15.6 83.5 57.6 45.9 34.3 35.2 32.2 92.5 57.6 40.8 49.4 67.8 71.3 47.1 52.2 80.8 53.8 48.4 23.1 54.2 74.7 55.8 20.2 13.6 25.5 15.9 18.6 15.6 21.7 16.3 18.9 12.4 25.1 16.9 18.6 4.3 18.0 28.5 25.0 24.8 12.3 36.8 39.3 40.0 56.0 37.5 40.9 40.2 39.7 41.4 39.9 39.0 42.0 30.6 32.1 22.5 9.8 37.0 16.2 35.9 96.7 21.1 23.9 33.2 29.6 92.3 37.1 42.6 38.6 12.5 113.9 34.1 34.6 189.8 56.9 111.0 40.0 27.1 34.9 53.3 25.7 15.4 60.9 70.5 30.9 20.4 25.3 58.3 21.6 33.5 32.0 82.6 18.5 18.8 47.7 57.0 35.8 24.0 34.2 34.8 30.2 39.2 10.3 66.8 55.6 46.4 21.1 27.1 50.3 39.7 36.9 25.4 28.8 56.3 163.0 58.9 33.4 46.0 36.9 44.1 82.9 60.4 18.8 14.9 61.3 33.3 42.7 46.3 35.4 NHEJ1 "Cernunnos, FLJ12610, XLF" ENSG00000187736 "Non-homologous end joining factor 1" Q9H9Q4 2 219069357-219160865 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" DNA-binding "Disease variant, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 7.8;Microglial cells: 11.2;Oligodendrocytes: 8.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012334, HPA043869" Approved Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 39: CACO-2 - Unknown function" "Cluster 59: Non-specific - Transcription" Nucleoplasm "Nucleoli fibrillar center" "CAB012334: , HPA043869: AB_2678707" "unprognostic (5.66e-2)" "unprognostic (3.01e-2)" "unprognostic (3.16e-1)" "unprognostic (2.73e-2)" "unprognostic (2.28e-1)" "unprognostic (1.06e-2)" "unprognostic (5.92e-2)" "unprognostic (5.16e-2)" "unprognostic (6.04e-2)" "unprognostic (3.51e-2)" "unprognostic (6.87e-2)" "unprognostic (1.58e-3)" "unprognostic (4.52e-2)" "unprognostic (1.65e-1)" "unprognostic (1.82e-1)" "unprognostic (8.90e-2)" "unprognostic (8.29e-2)" 10.2 8.4 2.4 4.4 2.5 4.5 8.5 3.8 3.8 9.4 2.2 14.0 6.9 8.7 4.3 7.2 7.4 4.8 6.2 2.4 2.9 12.8 8.1 6.9 6.1 3.3 2.5 9.1 8.4 3.4 2.8 4.6 3.2 6.7 8.4 3.4 5.7 4.3 17.1 8.4 12.2 8.1 2.7 6.9 9.0 18.7 2.7 6.1 4.6 7.6 5.8 10.4 8.7 3.5 5.5 8.2 13.9 12.6 15.6 17.9 8.0 10.9 9.6 13.2 15.4 25.4 5.9 12.2 8.4 11.4 13.4 7.2 20.5 10.9 11.8 13.8 9.0 18.1 10.0 17.5 12.5 8.5 13.9 15.5 21.2 10.5 12.5 8.9 11.1 7.8 22.3 11.8 10.7 4.6 11.5 10.3 15.9 5.1 8.0 14.6 10.2 9.8 10.5 8.2 10.2 11.4 5.0 7.1 15.8 15.6 6.4 8.0 9.9 10.0 9.3 4.4 9.1 6.3 8.0 13.2 6.1 16.2 10.3 6.3 11.9 6.6 7.0 17.7 12.2 12.0 11.4 9.3 8.7 9.0 14.1 10.4 3.3 11.6 15.6 4.8 12.8 9.1 2.4 2.5 3.8 3.8 2.4 2.9 3.3 2.5 3.2 2.7 2.7 3.5 0.3 0.0 0.0 5.9 3.5 0.4 0.0 0.2 5.7 0.0 0.2 0.1 0.1 0.0 0.7 0.0 0.0 0.2 1.7 7.8 0.0 1.6 0.7 0.1 0.3 1.0 2.4 3.8 4.7 1.9 0.3 0.6 5.6 0.2 0.0 0.0 0.0 0.3 0.3 0.0 5.1 3.4 0.0 0.0 0.0 0.2 0.3 2.1 0.0 11.2 3.1 0.0 0.0 5.0 8.1 1.0 2.9 0.0 6.1 0.2 3.4 0.4 0.0 0.0 0.0 0.1 1.3 0.2 0.5 5.9 0.0 0.3 2.6 0.2 3.1 0.0 NHLRC1 "bA204B7.2, EPM2B" ENSG00000187566 "NHL repeat containing E3 ubiquitin protein ligase 1" Q6VVB1 6 18120440-18122677 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Autophagy, Ubl conjugation pathway" Transferase "Disease variant, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Erythroid cells: 5.0;Exocrine glandular cells: 3.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "EFO-21: 6.8;K-562: 6.1;SCLC-21H: 6.1" "Low region specificity" "Detected in all" HPA066030 Uncertain Vesicles NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 15: Liver - Metabolism" "Cluster 1: K-562 - Erythropoiesis" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA066030: " "unprognostic (1.61e-1)" "unprognostic (1.39e-1)" "unprognostic (7.95e-2)" "prognostic unfavorable (9.01e-4)" "unprognostic (6.95e-3)" "unprognostic (2.45e-1)" "unprognostic (1.09e-1)" "unprognostic (3.69e-1)" "unprognostic (2.39e-1)" "unprognostic (7.17e-2)" "unprognostic (5.07e-3)" "unprognostic (1.28e-1)" "unprognostic (2.32e-2)" "unprognostic (3.19e-1)" "unprognostic (2.33e-1)" "unprognostic (2.77e-2)" "prognostic favorable (5.30e-4)" 1.2 1.4 2.0 0.8 2.3 1.1 2.0 1.5 2.6 0.8 0.8 1.5 1.4 0.8 2.6 1.1 1.4 0.6 1.8 2.4 1.9 0.8 4.1 1.2 0.6 2.5 1.8 1.4 1.8 1.2 1.2 0.5 2.7 1.2 1.3 2.0 2.3 1.0 2.6 3.8 1.9 0.8 1.6 1.1 1.3 0.7 2.0 1.0 1.6 1.5 0.8 0.9 0.8 3.6 2.6 1.5 0.6 0.0 1.3 1.2 0.0 2.6 0.8 0.9 0.5 0.1 2.1 0.0 6.8 1.9 0.2 3.0 0.0 1.7 0.7 0.1 0.9 0.4 1.0 0.1 2.0 0.0 1.7 2.1 2.5 1.0 0.9 0.6 2.1 0.0 6.1 0.1 2.1 2.8 0.0 0.0 0.0 0.3 1.5 0.0 0.0 0.1 1.4 2.8 6.1 0.1 5.3 4.3 1.6 0.6 3.1 1.7 0.4 0.2 1.3 1.8 0.1 0.1 0.0 0.1 0.1 0.0 2.6 0.5 4.4 0.4 0.6 4.9 0.8 2.3 1.1 0.5 4.7 1.3 1.5 1.0 0.3 1.6 2.3 0.6 1.3 1.8 2.0 2.3 1.5 2.6 2.4 1.9 2.5 1.8 2.7 1.6 2.0 3.6 0.8 0.0 2.2 0.3 0.2 1.9 1.4 1.4 1.8 0.4 1.5 2.0 0.9 1.5 2.3 0.0 0.0 0.4 0.0 0.2 0.0 2.9 0.0 0.6 1.3 0.3 3.5 5.0 1.0 3.7 0.0 0.8 1.5 0.5 1.3 0.8 0.4 1.1 1.2 0.0 0.7 0.3 0.0 0.8 0.6 0.0 0.6 1.5 1.8 1.0 0.5 1.1 0.0 1.5 1.2 2.0 0.3 0.0 0.0 0.2 0.6 1.2 0.8 1.0 0.0 0.3 0.8 0.2 0.2 1.3 1.8 0.4 0.1 1.1 0.5 0.5 NHSL2 ENSG00000204131 "NHS like 2" Q5HYW2 X 71910818-72161750 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 101.2;monocytes: 57.7;Prostatic glandular cells: 90.5;Urothelial cells: 80.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 14.3;neutrophil: 15.6" "Group enriched" "Detected in many" 4 "dendritic cells: 4.1;granulocytes: 15.6;monocytes: 7.1" "Cell line enhanced" "Detected in some" "AF22: 25.2;EFO-21: 29.5;HUVEC TERT2: 27.8;TIME: 16.3;U-937: 20.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049771, HPA075115" Uncertain Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cell Junctions" Nucleoplasm "HPA049771: AB_2680872, HPA075115: " "unprognostic (9.71e-3)" "unprognostic (1.96e-1)" "unprognostic (1.92e-1)" "unprognostic (4.56e-2)" "unprognostic (1.40e-1)" "unprognostic (5.50e-2)" "unprognostic (2.88e-2)" "unprognostic (5.72e-4)" "unprognostic (5.46e-2)" "unprognostic (3.36e-2)" "unprognostic (1.50e-2)" "unprognostic (1.91e-1)" "unprognostic (1.61e-2)" "unprognostic (4.27e-3)" "unprognostic (9.99e-2)" "unprognostic (7.76e-2)" "unprognostic (4.37e-4)" 4.7 1.3 8.1 3.0 9.6 2.2 3.2 11.8 6.6 3.2 12.3 4.9 0.8 3.2 1.4 3.1 2.3 4.3 2.2 6.6 5.9 1.1 0.9 3.4 0.8 1.5 9.1 1.6 0.6 1.6 2.6 2.2 4.6 3.5 1.9 0.3 1.5 4.8 0.8 1.4 1.7 6.9 0.8 2.8 1.9 2.4 6.9 1.0 2.7 2.4 0.9 3.7 2.3 0.0 0.4 0.6 25.2 0.1 0.3 1.0 0.2 0.9 4.7 0.1 0.4 0.1 0.0 0.2 29.5 2.6 0.1 0.0 1.6 0.0 0.6 0.1 0.6 0.1 0.1 0.0 0.1 0.1 1.4 0.5 0.0 0.9 0.0 0.1 27.8 0.1 0.0 4.1 0.2 0.2 0.1 2.1 4.8 0.0 0.0 0.1 1.4 0.0 0.1 2.9 0.6 5.7 0.0 0.0 0.0 7.1 0.1 1.7 16.3 0.0 1.6 2.0 0.0 0.1 0.0 0.1 1.1 20.5 0.0 5.0 7.1 14.3 2.0 4.7 1.9 0.0 1.0 1.7 4.1 0.0 0.1 0.2 15.6 1.0 3.7 0.0 0.1 2.3 8.1 9.6 11.8 6.6 6.6 5.9 1.5 9.1 4.6 0.8 6.9 0.0 29.2 0.0 1.9 1.0 7.3 0.5 101.2 0.0 0.6 0.9 5.0 3.7 19.6 21.5 0.0 1.8 0.0 17.9 10.1 2.0 0.0 0.2 4.7 3.3 2.8 32.9 1.2 17.3 7.8 0.7 24.3 15.2 0.5 9.0 7.6 0.9 51.0 19.0 19.1 0.0 5.8 3.7 0.0 49.0 0.5 7.4 31.7 19.7 1.8 19.7 57.7 1.5 32.0 5.5 1.1 0.6 3.1 21.4 2.8 90.5 7.8 2.9 0.0 0.5 26.3 39.7 12.6 2.7 3.7 0.3 0.3 24.9 17.0 2.9 3.8 80.7 NINJ2 ENSG00000171840 "Ninjurin 2" Q9NZG7 12 564296-663779 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 45.1" "Cell type enhanced" "Detected in many" "Adipocytes: 29.8;Alveolar cells type 2: 39.9;Erythroid cells: 35.4;Hofbauer cells: 30.7;Kupffer cells: 38.3;Oligodendrocytes: 109.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 153.5;MOLT-4: 263.8;THP-1: 54.4;U-698: 49.3" "Low region specificity" "Detected in all" "HPA058980, HPA067226" Approved "Nucleoplasm,Endoplasmic reticulum,Plasma membrane,Centriolar satellite,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 70: Brain - Nervous system development" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Endoplasmic reticulum" "Nucleoplasm, Plasma membrane, Centriolar satellite, Cytosol" "HPA058980: AB_2683869, HPA067226: " "unprognostic (1.16e-1)" "unprognostic (2.19e-1)" "unprognostic (9.51e-2)" "unprognostic (6.25e-3)" "unprognostic (1.37e-1)" "prognostic favorable (5.31e-4)" "unprognostic (5.72e-3)" "unprognostic (1.90e-3)" "unprognostic (4.60e-2)" "unprognostic (4.98e-3)" "unprognostic (5.88e-2)" "unprognostic (5.12e-2)" "unprognostic (2.68e-2)" "unprognostic (9.05e-2)" "unprognostic (1.03e-2)" "unprognostic (3.51e-3)" "unprognostic (1.23e-1)" 20.6 1.8 21.0 11.3 30.8 38.3 16.5 25.9 29.6 7.8 14.5 5.7 5.2 4.3 2.5 9.6 4.1 5.3 12.2 21.8 23.7 2.1 18.7 36.8 14.8 30.5 26.7 1.0 1.9 0.8 1.5 4.4 28.5 4.3 4.9 0.5 7.4 2.9 38.2 11.3 6.4 5.5 23.9 13.3 4.2 5.5 26.0 8.8 4.0 12.8 11.2 8.5 6.5 45.1 1.7 0.4 0.1 1.8 0.3 0.6 2.9 0.2 0.0 0.0 0.1 3.1 11.8 0.0 0.6 6.1 1.7 0.2 0.2 0.0 0.0 8.6 0.1 153.5 34.2 1.9 0.0 4.3 6.1 2.2 0.2 0.0 0.0 0.0 3.1 3.2 9.0 25.5 0.1 0.1 263.8 8.5 2.6 0.1 0.0 6.8 0.2 0.8 2.7 0.0 0.1 0.0 28.3 0.2 0.0 0.3 0.3 54.4 0.7 0.0 1.5 9.8 0.2 0.1 4.2 49.3 0.4 28.5 0.1 6.7 58.1 48.3 32.8 47.2 9.8 18.8 36.2 34.9 49.9 17.7 7.7 16.7 112.9 21.4 39.4 26.2 157.3 33.4 21.0 30.8 25.9 29.6 21.8 23.7 30.5 26.7 28.5 23.9 26.0 45.1 29.8 22.4 39.9 0.3 5.3 5.7 0.3 2.5 6.2 0.0 1.3 1.3 1.5 1.5 8.7 0.0 0.0 2.6 8.9 2.1 1.9 0.2 3.1 5.5 1.6 9.4 4.2 35.4 1.7 0.0 3.9 13.5 1.1 1.2 2.5 0.4 4.2 11.2 30.7 0.0 1.0 3.5 0.0 38.3 7.8 3.1 8.1 18.0 7.2 11.2 12.4 0.2 7.2 3.5 109.7 0.8 2.6 4.1 8.1 0.1 2.1 0.2 5.0 0.1 0.0 1.3 1.6 3.3 3.1 7.6 5.5 0.8 12.5 0.1 3.1 0.2 NINL "KIAA0980, NLP" ENSG00000101004 "Ninein like" Q9Y2I6 20 25452697-25585531 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 42.4;Granulosa cells: 29.6;Inhibitory neurons: 32.6;Oligodendrocyte precursor cells: 47.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 37.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA000686 Uncertain Uncertain "Microtubules,Cytokinetic bridge,Cytosol" Yes No "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 40: Granulosa cells - Unknown function" "Microtubules, Cytokinetic bridge, Cytosol" "HPA000686: AB_1079193" "unprognostic (7.33e-2)" "unprognostic (1.14e-1)" "unprognostic (1.13e-1)" "unprognostic (2.63e-2)" "unprognostic (4.84e-2)" "unprognostic (4.64e-2)" "unprognostic (1.16e-1)" "unprognostic (8.56e-2)" "unprognostic (2.50e-1)" "unprognostic (7.56e-2)" "prognostic favorable (1.47e-4)" "unprognostic (3.39e-1)" "prognostic favorable (1.03e-5)" "unprognostic (3.95e-2)" "unprognostic (2.72e-1)" "unprognostic (1.51e-1)" "unprognostic (6.26e-2)" 4.0 8.6 4.9 2.0 5.9 0.6 4.0 10.4 6.1 10.1 8.8 9.8 3.2 7.2 7.2 5.8 5.2 3.3 4.0 4.4 6.9 15.1 8.1 4.1 2.2 7.9 7.1 18.9 5.4 8.2 9.9 1.5 7.0 8.8 2.1 4.7 4.4 3.7 4.5 2.4 3.9 3.5 5.5 4.9 6.3 7.7 6.5 15.7 10.2 1.2 2.2 3.6 8.5 6.8 1.0 10.8 23.0 15.1 2.6 7.5 7.1 3.6 3.1 3.1 4.4 2.8 7.5 0.6 5.0 5.6 7.6 0.8 3.4 0.7 2.6 0.5 4.7 1.6 5.0 37.5 5.4 0.6 0.1 9.2 0.7 3.6 0.0 8.8 6.8 17.8 1.9 0.3 3.8 9.6 21.7 0.7 6.5 0.1 1.1 0.5 17.9 0.8 1.5 1.3 22.7 16.0 8.2 3.0 9.1 18.3 4.9 6.4 0.3 0.1 8.6 0.1 0.2 2.3 4.4 0.1 0.2 0.6 3.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 4.9 5.9 10.4 6.1 4.4 6.9 7.9 7.1 7.0 5.5 6.5 6.8 1.2 0.0 14.6 42.4 0.8 2.0 4.9 2.5 5.7 3.0 2.8 3.3 6.5 12.8 4.8 7.3 25.0 2.8 0.6 0.4 0.0 5.6 0.6 4.2 7.3 2.3 6.1 0.0 7.4 1.2 1.3 8.7 4.6 3.4 0.0 29.6 8.9 8.4 2.3 8.4 32.6 2.3 8.2 0.3 2.0 2.7 13.1 0.8 0.0 12.2 0.0 3.2 2.1 47.3 19.4 2.8 1.5 12.4 0.9 4.5 0.7 8.8 13.7 1.9 6.6 10.8 4.7 2.5 5.0 4.3 0.9 1.5 1.1 21.0 2.5 1.9 NIPAL3 "DJ462O23.2, NPAL3" ENSG00000001461 "NIPA like domain containing 3" Q6P499 1 24415802-24472976 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 88.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 110.5;Oligodendrocytes: 91.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ: 101.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039978 Approved Approved Nucleoplasm NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 70: Brain - Nervous system development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA039978: AB_10697712" "unprognostic (9.36e-2)" "unprognostic (7.63e-2)" "unprognostic (2.88e-2)" "unprognostic (1.19e-2)" "unprognostic (5.96e-2)" "unprognostic (5.38e-2)" "unprognostic (3.72e-3)" "unprognostic (3.60e-2)" "unprognostic (2.43e-1)" "unprognostic (6.66e-2)" "unprognostic (2.79e-1)" "unprognostic (3.14e-1)" "prognostic favorable (3.03e-7)" "unprognostic (1.46e-2)" "unprognostic (1.94e-1)" "prognostic favorable (3.95e-4)" "unprognostic (2.85e-1)" 8.4 7.4 49.6 8.4 67.3 8.4 12.9 67.7 58.5 9.6 25.8 13.8 11.3 6.2 11.7 15.9 14.6 8.9 12.8 43.6 58.1 13.8 3.5 13.9 11.6 61.8 58.6 7.2 17.1 21.9 7.3 3.5 65.0 55.9 14.4 27.7 15.2 7.6 5.9 14.0 12.7 12.3 56.1 7.8 14.8 4.9 65.0 13.2 29.2 11.9 13.1 8.0 10.4 88.5 32.4 12.1 1.1 4.2 18.9 20.7 4.5 101.8 71.7 35.0 26.2 4.5 36.4 15.4 30.2 55.2 7.3 31.5 12.5 37.1 37.3 29.5 38.1 16.0 18.5 5.4 17.7 14.2 14.4 20.7 36.1 22.3 75.7 34.8 12.2 27.5 9.5 9.7 22.4 7.2 11.5 6.6 8.3 15.4 34.0 5.5 0.1 17.1 41.6 10.1 44.6 4.3 13.1 19.5 26.9 8.6 26.0 10.6 17.9 31.5 6.7 10.9 22.9 29.4 24.1 5.4 21.4 26.8 28.8 16.9 5.8 7.9 16.7 5.7 16.9 22.1 28.8 22.5 11.2 20.1 38.9 24.8 2.5 15.6 4.2 14.6 31.8 16.0 49.6 67.3 67.7 58.5 43.6 58.1 61.8 58.6 65.0 56.1 65.0 88.5 17.1 48.1 27.5 8.8 15.4 9.2 13.5 25.7 14.8 50.3 15.9 12.2 25.9 15.7 24.7 40.5 110.5 3.8 32.1 25.0 3.9 13.1 3.6 11.0 3.5 10.2 18.7 26.1 29.3 15.5 4.7 7.4 16.8 18.3 13.3 10.5 9.3 3.8 4.5 13.5 32.2 16.7 16.2 7.0 7.8 8.0 4.1 5.5 14.2 10.3 8.6 18.7 23.7 24.6 91.8 22.6 22.6 5.3 16.0 34.5 33.2 4.5 16.5 53.6 0.0 4.4 5.9 2.6 6.0 20.0 16.3 4.2 25.3 8.2 17.2 20.9 NKAPL "bA424I5.1, C6orf194" ENSG00000189134 "NFKB activating protein like" Q5M9Q1 6 28259297-28260958 "Predicted intracellular proteins" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 12.6;testis: 32.3" "Group enriched" "Detected in many" 4 "Early spermatids: 401.2;Spermatocytes: 307.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "ASC diff: 3.2;BJ: 1.4;fHDF/TERT166: 2.2;HHSteC: 4.6;HSkMC: 3.0;HUVEC TERT2: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (3.93e-2)" "unprognostic (2.08e-2)" "unprognostic (1.46e-2)" "unprognostic (9.73e-2)" "unprognostic (2.47e-1)" "unprognostic (7.86e-2)" "unprognostic (2.34e-2)" "unprognostic (1.86e-2)" "unprognostic (1.34e-1)" "unprognostic (1.88e-2)" "unprognostic (3.84e-3)" "unprognostic (5.78e-2)" "unprognostic (5.83e-5)" "unprognostic (6.65e-3)" "unprognostic (2.38e-1)" "unprognostic (2.08e-2)" "unprognostic (2.47e-2)" 1.9 1.3 5.9 0.7 5.9 0.2 1.5 6.4 9.0 0.8 5.0 2.2 0.2 1.1 1.1 0.9 0.7 0.7 5.0 5.6 6.1 2.0 0.8 0.7 0.7 6.8 6.3 2.0 1.5 0.3 2.1 0.8 6.7 1.4 0.4 12.6 1.6 2.5 5.6 0.7 0.7 1.4 6.1 1.3 1.1 32.3 6.4 0.5 1.0 4.0 0.5 2.0 0.5 6.6 0.0 0.0 0.0 0.0 3.2 0.9 0.0 1.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 3.0 0.0 0.2 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.0 1.6 0.1 1.3 0.3 1.2 0.0 0.2 0.9 0.1 0.2 0.2 2.2 0.3 1.0 2.5 0.0 0.2 5.9 5.9 6.4 9.0 5.6 6.1 6.8 6.3 6.7 6.1 6.4 6.6 4.2 0.0 0.0 2.6 1.1 1.0 1.6 2.5 0.0 29.5 1.8 3.7 13.0 1.5 2.6 1.8 43.8 0.1 4.7 0.0 9.8 2.1 401.2 0.4 2.5 4.8 0.0 0.0 3.3 0.7 0.0 4.1 0.0 0.2 0.0 1.4 3.9 3.5 3.2 33.7 3.3 0.1 10.2 5.1 3.1 49.2 5.6 2.7 5.4 1.9 3.6 15.7 2.1 1.0 2.1 1.4 0.0 6.4 0.4 1.6 0.1 4.1 1.3 77.4 0.0 3.1 5.7 307.1 28.1 1.1 0.9 0.3 1.9 3.2 0.1 0.6 NLGN3 "ASPGX1, AUTSX1, HNL3, KIAA1480" ENSG00000196338 "Neuroligin 3" Q9NZ94 X 71144831-71171201 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Asperger syndrome, Autism, Autism spectrum disorder, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.1;seminal vesicle: 12.5" "Cell type enhanced" "Detected in some" "Astrocytes: 19.6;Inhibitory neurons: 12.7;Oligodendrocyte precursor cells: 92.0;Oligodendrocytes: 43.7;Peritubular cells: 17.3" "Cancer enriched" "Detected in many" 19 "glioma: 37.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 6.7;NTERA-2: 5.3;SH-SY5Y: 2.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003183, HPA004066" Enhanced Supported "Golgi apparatus,Cell Junctions" "Intracellular and membrane" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" "Golgi apparatus, Cell Junctions" "HPA003183: AB_1079469, HPA004066: AB_2732397" "unprognostic (4.06e-2)" "unprognostic (1.77e-1)" "unprognostic (1.59e-2)" "unprognostic (2.38e-2)" "unprognostic (2.42e-1)" "unprognostic (3.87e-1)" "unprognostic (6.52e-2)" "unprognostic (1.63e-1)" "unprognostic (7.10e-2)" "unprognostic (1.17e-1)" "unprognostic (1.94e-1)" "unprognostic (6.18e-2)" "unprognostic (4.27e-9)" "unprognostic (4.28e-2)" "unprognostic (1.90e-1)" "unprognostic (2.22e-5)" "unprognostic (9.01e-2)" 0.5 6.6 10.1 0.8 8.5 1.4 0.4 6.4 11.1 1.9 0.0 1.8 0.2 2.7 6.4 0.6 4.3 1.4 1.1 10.3 10.2 0.3 0.1 0.6 0.4 7.3 7.0 4.4 0.3 0.5 1.0 0.6 4.8 6.0 0.5 1.9 0.6 12.5 0.1 0.7 0.7 1.9 5.5 0.6 0.6 2.6 7.3 0.4 0.4 0.4 0.2 0.7 1.2 9.7 0.0 0.5 6.7 0.2 1.6 0.6 1.2 0.0 0.0 0.0 0.1 0.1 0.3 0.5 0.5 0.1 0.0 0.1 0.2 0.0 0.1 0.4 0.9 0.4 0.4 0.0 0.0 0.1 0.4 0.4 0.1 0.2 0.0 0.3 0.1 2.0 0.5 1.5 0.0 0.3 0.5 1.2 5.3 0.0 0.0 0.6 0.2 0.3 0.0 0.8 1.7 2.5 0.2 0.0 0.6 0.8 0.0 0.3 0.1 0.1 0.8 0.2 0.0 1.1 1.1 0.5 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 10.1 8.5 6.4 11.1 10.3 10.2 7.3 7.0 4.8 5.5 7.3 9.7 0.3 0.0 0.0 19.6 0.0 0.6 0.3 0.2 1.2 2.6 0.3 0.9 0.4 0.0 0.1 0.0 0.0 1.0 0.2 0.2 0.0 0.1 1.3 0.2 1.1 0.5 0.0 0.0 11.3 0.0 0.2 1.3 0.0 0.4 0.0 1.0 0.7 0.0 0.1 0.0 12.7 0.0 0.0 0.0 0.8 3.9 2.1 0.2 0.0 2.8 0.1 2.5 0.0 92.0 43.7 0.2 0.1 17.3 0.0 0.2 0.0 0.0 0.0 0.7 0.0 0.2 0.6 0.2 0.0 0.1 0.4 0.3 0.2 4.5 0.1 0.3 NMBR "BB1, BB1R" ENSG00000135577 "Neuromedin B receptor" P28336 6 142058330-142088799 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.5;testis: 1.4" "Cell type enhanced" "Detected in some" "Astrocytes: 3.3;Early spermatids: 7.0;Excitatory neurons: 2.3;Inhibitory neurons: 4.5;Late spermatids: 2.1;Oligodendrocyte precursor cells: 2.0;Oligodendrocytes: 2.5;Spermatocytes: 3.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA026665 Supported "Plasma membrane,Cytosol" NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cytosol" "HPA026665: AB_1854527" "unprognostic (6.24e-2)" "unprognostic (3.05e-1)" "unprognostic (2.77e-2)" "unprognostic (7.88e-2)" "unprognostic (3.54e-2)" "unprognostic (8.21e-2)" "unprognostic (3.63e-2)" "unprognostic (1.54e-1)" "unprognostic (3.95e-1)" "unprognostic (7.94e-3)" "unprognostic (3.44e-1)" "unprognostic (2.11e-1)" "unprognostic (8.45e-2)" 0.0 0.0 0.7 0.0 1.0 0.0 0.1 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.8 0.0 0.0 0.2 1.3 0.0 0.0 0.1 0.0 1.0 1.1 0.1 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.0 0.0 1.4 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.0 0.0 0.6 0.2 1.3 1.0 1.1 1.5 1.1 0.5 0.2 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.3 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 2.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NME8 "CILD6, NM23-H8, SPTRX2, TXNDC3" ENSG00000086288 "NME/NM23 family member 8" Q8N427 7 37848597-37900397 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Ciliopathy, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "bone marrow: 12.3;testis: 10.4" "Cell type enhanced" "Detected in some" "dendritic cells: 22.8;Early spermatids: 46.3;Late spermatids: 23.4;NK-cells: 17.5;Oligodendrocytes: 9.8;Spermatocytes: 26.5" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 4.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HMC-1: 1.2;NB-4: 2.0;NTERA-2: 1.7;THP-1: 1.7;U-937: 5.3" "Not detected" "Not detected" "Not detected" "Not detected" "CAB016416, HPA019259, HPA029572" Enhanced Supported "Nuclear speckles,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "Nuclear speckles" "CAB016416: , HPA019259: AB_1858475, HPA029572: " "unprognostic (7.44e-3)" "unprognostic (2.32e-2)" "unprognostic (9.11e-2)" "unprognostic (2.97e-2)" "unprognostic (6.05e-2)" "unprognostic (1.20e-2)" "unprognostic (6.56e-2)" "unprognostic (4.22e-2)" "unprognostic (7.17e-2)" "unprognostic (1.05e-1)" "unprognostic (3.24e-1)" "unprognostic (2.34e-2)" "unprognostic (8.13e-8)" "unprognostic (5.90e-2)" "unprognostic (3.36e-1)" "unprognostic (1.49e-1)" "unprognostic (1.86e-1)" 0.1 0.1 0.4 0.6 0.9 12.3 0.1 0.5 0.7 0.1 0.5 0.3 0.1 0.1 0.1 0.2 0.1 0.5 0.0 0.3 0.7 0.0 0.1 0.4 0.5 1.1 0.6 0.0 0.0 0.0 0.0 0.2 0.9 0.1 0.1 0.0 0.1 0.1 0.0 0.4 0.2 0.1 0.7 1.0 0.2 10.4 0.9 0.3 0.0 0.0 0.3 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.2 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 1.1 0.9 0.3 0.2 0.0 0.0 0.0 0.7 0.9 0.0 0.0 0.3 2.1 0.1 0.0 4.6 0.0 0.4 0.4 0.9 0.5 0.7 0.3 0.7 1.1 0.6 0.9 0.7 0.9 1.0 0.1 0.0 2.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.1 22.8 0.0 0.0 0.0 46.3 0.0 0.1 0.1 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 5.1 0.0 0.0 0.0 0.8 0.0 0.4 0.0 0.0 1.9 5.1 23.4 0.0 3.3 0.0 0.0 2.6 0.0 17.5 0.0 9.8 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 26.5 0.7 0.0 0.0 0.0 2.2 0.0 0.0 0.0 NME9 "NM23-H9, TXL-2, TXNDC6" ENSG00000181322 "NME/NM23 family member 9" Q86XW9 3 138261437-138329886 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 14.6;fallopian tube: 17.6" "Group enriched" "Detected in some" 6 "Astrocytes: 27.4;Endometrial ciliated cells: 20.0;Excitatory neurons: 26.6;Inhibitory neurons: 17.9;Oligodendrocyte precursor cells: 67.8;Oligodendrocytes: 36.6;Respiratory ciliated cells: 48.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 1.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB020943, HPA040000, HPA043881" Enhanced Approved "Centriolar satellite,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 3: HMC-1 - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "Centriolar satellite" "CAB020943: , HPA040000: AB_2676793, HPA043881: AB_2678712" "unprognostic (2.71e-5)" "unprognostic (1.68e-1)" "unprognostic (5.09e-2)" "unprognostic (3.01e-3)" "unprognostic (3.67e-1)" "unprognostic (1.69e-3)" "unprognostic (4.58e-2)" "unprognostic (5.19e-2)" "unprognostic (1.66e-1)" "unprognostic (1.12e-2)" "unprognostic (1.03e-2)" "unprognostic (1.72e-2)" "unprognostic (3.82e-2)" "unprognostic (1.39e-2)" "unprognostic (9.14e-2)" "unprognostic (4.89e-2)" "unprognostic (7.17e-3)" 0.7 0.7 4.1 0.4 4.0 2.9 0.7 8.8 5.5 1.1 14.6 0.6 0.2 0.6 0.7 0.4 17.6 0.4 0.5 3.4 4.1 1.0 0.4 2.2 0.3 6.9 7.0 0.7 1.3 0.9 3.7 0.2 4.2 0.8 0.0 7.4 1.6 0.7 2.7 0.8 0.8 0.2 5.2 0.5 0.6 4.3 5.0 0.5 1.1 0.0 0.2 0.5 0.5 4.4 0.3 0.2 0.4 0.1 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.2 0.3 0.6 0.2 0.0 0.2 0.4 0.0 0.0 0.0 0.1 0.2 0.7 0.8 0.1 0.0 1.0 1.7 0.3 0.0 0.0 0.0 0.7 0.0 0.7 0.2 0.4 0.0 0.1 0.1 1.0 0.2 0.1 0.3 0.3 0.0 0.3 0.5 0.9 0.9 0.2 0.6 0.1 0.1 0.3 0.3 0.0 1.1 0.3 0.2 0.3 0.1 0.3 0.4 0.4 0.2 0.4 0.2 0.0 0.2 0.0 0.0 0.0 0.6 0.1 0.3 0.0 0.1 0.2 0.4 0.1 0.1 0.1 0.0 0.2 0.2 0.0 4.1 4.0 8.8 5.5 3.4 4.1 6.9 7.0 4.2 5.2 5.0 4.4 0.2 0.0 0.5 27.4 0.0 0.0 0.2 1.1 0.0 1.5 0.1 0.0 1.5 2.8 2.3 1.8 0.0 0.1 0.0 0.0 0.0 0.2 3.1 20.0 0.2 0.3 0.0 0.0 26.6 0.0 0.0 0.4 0.0 0.5 0.0 0.3 0.4 0.0 0.0 3.3 17.9 0.0 0.0 0.3 0.0 1.4 0.3 0.0 0.0 1.0 0.0 2.7 0.0 67.8 36.6 0.0 0.0 0.0 0.3 0.2 0.0 0.5 48.4 2.3 0.0 0.5 0.7 5.0 0.7 0.0 0.0 0.3 0.2 0.4 0.0 0.1 NMT2 ENSG00000152465 "N-myristoyltransferase 2" O60551 10 15102584-15168693 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 93.6;Hepatocytes: 141.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "basophil: 14.5;eosinophil: 13.6;gdT-cell: 11.0;MAIT T-cell: 19.8;memory CD4 T-cell: 17.5;memory CD8 T-cell: 12.9;naive CD4 T-cell: 21.8;naive CD8 T-cell: 14.5;NK-cell: 20.8;T-reg: 29.5" "Group enriched" "Detected in many" 8 "granulocytes: 14.5;NK-cells: 20.8;T-cells: 29.5" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 102.6;TIME: 147.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001303 Approved Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 2: Hepatocytes - Metabolism" "Golgi apparatus, Plasma membrane, Cytosol" "HPA001303: AB_1079494" "unprognostic (1.08e-1)" "unprognostic (7.65e-2)" "unprognostic (8.78e-2)" "unprognostic (1.15e-3)" "unprognostic (6.97e-2)" "unprognostic (2.24e-1)" "unprognostic (7.11e-2)" "unprognostic (5.13e-2)" "unprognostic (3.20e-1)" "unprognostic (4.01e-3)" "unprognostic (3.31e-1)" "unprognostic (2.00e-1)" "unprognostic (7.06e-2)" "unprognostic (3.79e-3)" "unprognostic (2.00e-1)" "unprognostic (1.03e-1)" "unprognostic (1.16e-1)" 25.9 4.4 7.3 6.1 8.7 3.7 17.5 12.2 10.0 9.8 4.0 8.8 6.6 12.7 3.5 7.0 8.3 7.0 8.7 7.0 4.9 9.4 16.8 6.3 8.9 5.0 7.6 15.4 5.6 16.5 5.5 4.4 5.1 9.0 9.2 7.0 5.2 7.7 8.3 10.1 10.9 10.5 4.3 9.4 7.9 13.4 9.1 27.0 5.9 8.5 8.0 8.6 7.9 7.3 8.8 11.3 12.7 9.3 33.7 35.9 2.3 18.8 15.3 17.0 23.0 10.9 38.7 0.4 12.7 102.6 46.6 10.6 11.4 10.7 28.3 11.7 13.9 23.4 5.4 15.2 22.4 1.7 84.0 31.9 10.8 23.8 7.2 62.2 65.8 16.3 11.2 1.5 63.7 10.9 18.3 4.4 9.3 10.0 10.5 13.6 18.5 1.8 12.6 1.8 3.9 14.4 22.8 3.7 6.3 10.5 11.7 7.3 147.1 16.7 24.4 75.0 13.7 13.0 14.3 1.0 20.7 6.3 12.4 14.5 0.5 13.6 11.0 0.7 19.8 2.2 17.5 12.9 0.5 2.5 21.8 14.5 1.9 20.8 0.8 0.5 29.5 6.5 7.3 8.7 12.2 10.0 7.0 4.9 5.0 7.6 5.1 4.3 9.1 7.3 52.5 9.6 8.8 25.1 16.0 16.6 23.4 8.3 7.4 20.6 14.7 13.1 13.5 57.2 10.9 27.6 4.2 1.3 16.9 32.8 9.8 33.9 6.6 4.7 20.5 21.7 18.0 15.1 39.6 19.5 3.0 16.3 9.2 10.3 93.6 13.2 25.4 141.9 2.8 20.2 30.1 11.4 4.1 7.9 7.1 14.5 21.8 5.8 12.4 17.8 10.1 12.9 40.2 12.5 15.3 27.1 15.9 20.7 10.0 17.9 38.4 63.2 5.3 17.2 0.0 13.4 21.0 8.1 46.8 6.8 14.8 2.6 33.9 11.0 18.1 16.7 NNMT ENSG00000166741 "Nicotinamide N-methyltransferase" P40261 11 114257787-114313536 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 388.9" "Group enriched" "Detected in many" 6 "Hepatocytes: 3913.2;Skeletal myocytes: 1639.1" "Cancer enhanced" "Detected in all" "renal cancer: 204.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HSkMC: 255.3;LHCN-M2: 144.1;RPTEC TERT1: 479.6" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA059180 Approved Approved "Golgi apparatus,Cytosol" NA NA 410000 "Cluster 85: Liver - Metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 2: Hepatocytes - Metabolism" "Golgi apparatus" Cytosol "HPA059180: AB_2683940" "unprognostic (1.62e-1)" "unprognostic (2.33e-2)" "unprognostic (1.61e-2)" "unprognostic (6.14e-2)" "unprognostic (3.51e-1)" "prognostic unfavorable (2.07e-4)" "unprognostic (1.76e-1)" "unprognostic (5.84e-2)" "unprognostic (2.71e-2)" "unprognostic (2.48e-2)" "unprognostic (1.20e-1)" "unprognostic (1.69e-2)" "prognostic unfavorable (1.02e-6)" "prognostic unfavorable (1.75e-4)" "unprognostic (1.11e-1)" "unprognostic (3.37e-3)" "unprognostic (2.77e-2)" 130.9 11.4 1.0 25.2 1.1 0.9 91.9 1.4 1.5 36.0 1.9 37.1 1.5 31.0 2.8 15.4 55.0 43.1 35.5 1.3 1.4 24.1 388.9 64.6 9.6 3.9 1.6 21.3 11.4 1.6 10.6 23.8 2.2 31.9 8.7 0.3 21.1 3.1 73.1 49.3 32.2 30.1 1.7 36.7 30.1 2.2 1.2 2.7 33.0 5.3 8.8 48.6 33.9 3.1 0.2 17.6 0.3 18.6 92.0 118.3 0.1 21.2 58.7 35.2 69.2 0.0 17.5 0.2 58.1 45.1 4.2 0.2 0.0 8.0 34.1 0.2 0.0 0.2 16.7 0.0 123.3 0.2 0.0 255.3 89.4 24.1 37.3 29.8 50.1 0.1 0.3 0.2 144.1 0.1 0.1 0.2 0.1 0.0 0.5 0.2 79.0 0.0 479.6 0.1 0.2 0.2 97.7 0.1 0.3 5.3 0.0 0.2 37.4 18.3 34.3 23.8 3.1 0.3 0.3 0.4 6.4 0.3 1.4 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 1.0 1.1 1.4 1.5 1.3 1.4 3.9 1.6 2.2 1.7 1.2 3.1 411.8 44.8 411.3 1.0 11.2 103.6 13.2 16.5 2.2 1.9 38.5 73.9 4.7 75.8 13.3 80.9 0.0 1.0 1.6 0.0 9.8 238.3 0.3 19.0 89.9 190.0 5.3 147.2 1.3 157.0 2.5 452.2 5.1 80.5 13.9 0.5 195.2 3913.2 28.4 0.0 1.6 0.0 0.0 126.8 142.1 1.6 74.3 9.2 96.0 1.9 5.7 0.0 0.0 0.0 0.2 323.1 0.0 13.2 1.5 10.8 0.0 99.2 11.9 0.2 0.0 1639.1 154.3 0.3 0.8 1.9 92.1 2.2 20.1 0.0 0.0 3.1 NOCT "Ccr4c, CCR4L, CCRN4L, NOC" ENSG00000151014 Nocturnin Q9UK39 4 139015781-139045939 "Predicted intracellular proteins" "Biological rhythms" "Hydrolase, Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 36.3" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 14.6;Glandular and luminal cells: 20.6;Syncytiotrophoblasts: 12.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012287, HPA053714" Uncertain Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 32: U-937 - Innate immune response" "Cluster 41: Macrophages - Immune response" "Nuclear bodies" "Nucleoplasm, Cytosol" "HPA012287: AB_2668640, HPA053714: AB_2682238" "unprognostic (2.16e-1)" "unprognostic (2.16e-3)" "unprognostic (1.47e-1)" "unprognostic (2.29e-1)" "unprognostic (3.36e-3)" "unprognostic (2.00e-3)" "unprognostic (3.24e-1)" "prognostic unfavorable (5.28e-5)" "unprognostic (1.86e-1)" "unprognostic (5.64e-3)" "unprognostic (4.63e-2)" "unprognostic (1.01e-3)" "prognostic unfavorable (1.05e-5)" "unprognostic (2.54e-1)" "unprognostic (1.14e-1)" "unprognostic (3.52e-4)" "prognostic unfavorable (6.23e-4)" 8.2 2.0 2.8 3.2 2.6 36.3 4.5 1.7 7.1 1.4 0.0 1.8 1.2 1.6 0.5 1.9 1.0 5.5 2.9 5.0 2.9 3.6 13.9 2.9 2.1 1.5 3.4 0.6 3.0 1.7 2.2 5.6 2.6 1.0 1.6 3.4 1.6 0.5 6.5 2.2 2.2 3.0 1.4 1.7 1.7 2.2 4.4 1.9 1.5 6.1 2.6 4.9 1.3 2.9 6.5 7.1 2.9 5.7 6.6 2.7 17.2 9.4 6.9 13.7 10.0 10.3 2.8 22.7 7.4 7.3 18.4 4.5 15.8 8.9 13.7 9.5 6.1 10.3 4.4 8.7 6.2 15.3 6.0 3.2 4.4 15.4 10.4 2.7 6.3 4.3 18.6 7.0 6.6 8.0 10.0 7.8 10.1 3.0 8.1 8.5 8.6 7.7 9.4 4.3 11.3 7.3 6.0 6.8 5.6 11.2 5.0 11.2 8.7 7.7 9.4 7.2 11.8 5.9 5.5 14.0 7.0 29.8 9.9 0.8 0.5 0.3 1.0 0.6 0.5 0.4 0.4 0.5 0.2 0.7 0.3 0.6 2.7 0.6 1.6 0.6 0.3 0.1 2.8 2.6 1.7 7.1 5.0 2.9 1.5 3.4 2.6 1.4 4.4 2.9 10.9 9.6 1.1 0.0 2.8 0.0 2.7 0.0 5.7 5.6 2.7 2.5 0.0 1.5 0.6 0.0 14.6 6.1 4.7 0.6 1.9 2.3 0.7 10.4 6.3 2.6 0.0 1.7 0.0 0.2 11.8 2.9 6.1 20.6 2.5 0.8 1.1 2.6 1.5 1.7 0.0 0.4 0.0 1.6 0.0 0.1 0.9 6.9 0.0 0.0 0.1 0.6 4.1 0.0 0.0 2.5 0.0 0.0 5.5 2.5 2.6 4.0 0.7 5.2 0.0 5.4 4.3 1.0 3.9 6.5 0.0 12.0 4.3 0.8 0.2 2.3 NODAL ENSG00000156574 "Nodal growth differentiation factor" Q96S42 10 70431936-70447951 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cytokine, Developmental protein, Growth factor" "Disease variant, Heterotaxy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.3;skeletal muscle: 2.3" "Group enriched" "Detected in some" 26 "Early spermatids: 15.4;Late spermatids: 38.5" "Cancer enriched" "Detected in some" 10 "testis cancer: 20.8" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 1.9;SH-SY5Y: 1.4;SuSa: 3.5" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA045201 Uncertain "Secreted to blood" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 25: Spermatids - Spermatogenesis" "HPA045201: AB_2679252" "unprognostic (3.07e-2)" "unprognostic (2.10e-1)" "unprognostic (1.51e-2)" "unprognostic (2.41e-1)" "unprognostic (1.70e-1)" "unprognostic (4.57e-2)" "unprognostic (1.50e-1)" "unprognostic (1.65e-1)" "unprognostic (5.66e-3)" "unprognostic (3.12e-2)" "unprognostic (8.77e-2)" "unprognostic (1.61e-1)" "unprognostic (1.63e-5)" "unprognostic (4.37e-1)" "unprognostic (6.98e-2)" "unprognostic (1.19e-1)" "unprognostic (2.02e-1)" 0.7 0.0 0.7 0.0 0.6 0.6 0.5 2.3 0.6 0.6 0.0 0.4 0.2 0.3 0.0 0.3 0.3 0.2 0.3 0.5 0.6 0.1 0.1 0.4 0.2 0.7 0.6 0.3 0.1 0.0 0.1 0.2 0.7 0.2 0.0 1.3 0.2 0.0 2.3 1.0 0.2 0.0 0.5 0.2 0.2 1.9 0.6 0.2 0.1 0.0 0.0 0.4 0.4 0.6 0.3 0.2 0.8 0.9 0.0 0.0 0.1 0.0 0.0 0.1 0.0 1.9 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.5 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.0 0.2 0.1 0.2 0.5 0.2 0.0 0.2 0.2 0.5 0.0 0.1 0.1 1.4 0.4 0.1 0.0 3.5 0.4 0.1 0.0 0.0 0.2 0.1 0.1 0.5 1.1 1.2 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.6 2.3 0.6 0.5 0.6 0.7 0.6 0.7 0.5 0.6 0.6 0.7 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 15.4 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 38.5 0.9 0.0 0.0 1.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 NOL12 "MGC3731, Nop25, RRP17" ENSG00000273899 "Nucleolar protein 12" Q9UGY1 22 37681673-37693476 "Predicted intracellular proteins" "RNA-binding, rRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 105.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA003547 Uncertain Approved "Nucleoplasm,Nucleoli,Mitotic chromosome,Vesicles" Yes No "Cluster 34: Basophils - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nucleoli, Mitotic chromosome" "Nucleoplasm, Vesicles" "HPA003547: AB_10602012" "unprognostic (3.37e-2)" "prognostic favorable (6.80e-5)" "unprognostic (2.65e-1)" "unprognostic (9.62e-2)" "unprognostic (2.13e-1)" "unprognostic (7.89e-2)" "unprognostic (3.23e-3)" "prognostic favorable (9.41e-4)" "unprognostic (9.96e-2)" "unprognostic (4.62e-2)" "unprognostic (2.18e-3)" "unprognostic (4.60e-2)" "prognostic unfavorable (2.56e-6)" "unprognostic (1.34e-2)" "unprognostic (8.40e-2)" "unprognostic (4.65e-2)" "prognostic favorable (3.24e-4)" 17.1 29.2 11.3 15.1 12.7 28.7 17.5 12.1 18.0 20.5 9.6 21.3 14.9 15.5 7.9 35.1 16.2 9.0 18.6 11.8 12.3 22.0 16.2 14.3 20.9 12.3 11.8 18.5 17.5 11.5 16.5 8.1 12.1 19.8 9.5 4.9 20.5 4.4 12.6 22.7 19.5 6.6 11.2 26.5 18.8 10.4 11.8 16.1 23.1 8.2 12.6 17.1 23.3 12.9 38.3 33.5 24.4 29.5 8.1 7.8 32.2 17.1 7.7 7.4 8.4 20.0 15.7 30.2 9.8 6.2 8.1 41.4 11.6 50.0 2.2 34.4 51.9 26.3 28.9 43.6 21.3 59.3 38.2 9.6 12.4 31.2 11.7 10.0 15.3 16.7 19.8 26.9 6.8 32.3 36.4 48.0 29.5 16.6 46.7 48.5 16.7 24.7 18.2 10.1 19.2 40.3 22.1 19.5 30.8 2.7 26.9 31.0 22.9 34.2 32.5 24.8 34.5 24.0 29.9 41.0 33.3 46.2 40.0 57.3 24.4 26.9 15.1 28.4 11.7 14.1 14.8 13.6 17.6 15.8 14.8 12.6 53.1 16.7 33.8 13.6 22.3 11.9 11.3 12.7 12.1 18.0 11.8 12.3 12.3 11.8 12.1 11.2 11.8 12.9 10.9 3.2 15.3 4.9 15.3 39.0 13.7 33.0 25.0 11.0 10.2 7.7 3.5 7.2 20.3 14.7 6.2 19.4 11.0 35.6 3.9 25.7 105.7 5.4 5.0 12.9 12.6 8.8 11.4 29.1 16.2 10.2 15.8 4.7 15.2 9.7 10.8 6.2 13.9 28.6 10.9 24.8 20.3 10.7 21.8 48.3 9.9 12.7 21.4 2.8 17.7 13.8 18.6 5.5 8.2 22.4 39.9 11.3 14.0 8.6 27.4 7.8 15.9 8.3 13.1 10.0 10.6 14.5 25.9 45.4 39.8 19.8 14.3 9.7 24.1 14.5 NOL4L "C20orf112, C20orf113, dJ1184F4.2, dJ1184F4.4, DKFZP566G1424" ENSG00000197183 "Nucleolar protein 4 like" Q96MY1 20 32443059-32585074 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 49.3;testis: 50.0" "Cell type enhanced" "Detected in many" "Early spermatids: 107.4;Late spermatids: 171.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CACO-2: 73.4;HEL: 58.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041768, HPA043600" Enhanced Enhanced Nucleoplasm NA Yes "Cluster 27: Non-specific - Gene expression" "Cluster 77: Retina - Visual perception" "Cluster 39: CACO-2 - Unknown function" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "HPA041768: AB_10964172, HPA043600: AB_10961001" "unprognostic (4.33e-2)" "unprognostic (1.71e-1)" "unprognostic (4.03e-1)" "prognostic unfavorable (1.01e-4)" "unprognostic (3.10e-1)" "unprognostic (7.88e-2)" "unprognostic (2.75e-3)" "unprognostic (1.65e-2)" "unprognostic (1.83e-1)" "unprognostic (1.41e-1)" "unprognostic (1.84e-1)" "unprognostic (1.72e-1)" "unprognostic (3.88e-2)" "unprognostic (9.32e-2)" "unprognostic (3.42e-1)" "unprognostic (6.08e-3)" "prognostic favorable (2.63e-4)" 10.4 9.1 12.8 8.7 17.5 20.8 10.2 20.8 19.9 8.7 3.1 17.2 18.7 6.6 12.0 2.5 8.6 8.6 5.6 13.2 14.7 14.5 7.0 13.4 8.0 14.5 13.5 4.0 11.1 4.3 22.3 11.1 14.8 8.7 13.6 49.3 9.7 8.2 1.6 3.5 19.8 6.5 10.3 12.9 13.2 50.0 13.1 15.1 9.7 1.7 5.8 9.7 5.2 19.5 9.1 27.4 16.9 11.6 3.6 5.4 2.3 5.7 4.6 7.1 4.9 73.4 20.8 0.6 16.6 7.5 11.0 2.5 5.4 15.9 3.2 2.1 4.3 58.2 14.5 53.2 9.3 0.9 3.3 13.6 2.2 5.2 3.4 16.1 43.1 12.5 17.7 7.6 3.4 5.1 19.3 17.8 9.9 27.7 25.3 8.2 2.1 3.0 12.0 1.6 22.3 18.1 17.9 0.4 9.8 17.4 3.7 17.8 45.5 6.6 22.6 6.1 5.9 5.6 2.1 4.0 7.2 31.4 20.3 2.9 2.0 1.2 5.8 4.5 5.1 1.6 3.8 3.4 2.1 1.1 7.6 6.4 6.5 8.3 12.1 0.2 6.9 4.9 12.8 17.5 20.8 19.9 13.2 14.7 14.5 13.5 14.8 10.3 13.1 19.5 23.1 6.4 3.3 7.2 4.1 0.0 10.8 0.0 2.2 49.9 20.8 18.3 8.8 11.5 1.3 12.9 66.7 0.3 29.5 57.9 9.8 8.0 107.4 9.4 2.9 25.3 17.5 4.6 29.7 7.8 2.1 5.8 20.4 8.7 12.0 11.1 21.8 4.7 9.8 8.4 22.0 36.6 0.0 3.3 0.0 171.5 5.6 8.6 0.0 33.7 6.1 17.2 24.7 14.1 51.2 14.0 36.6 4.9 9.0 15.2 59.4 24.0 2.2 57.3 19.7 1.7 5.0 75.3 3.8 0.8 0.0 0.4 16.5 16.9 29.5 28.7 NOS3 "ECNOS, eNOS" ENSG00000164867 "Nitric oxide synthase 3" P29474 7 150991017-151014588 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Calmodulin-binding, Oxidoreductase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 62.4" "Cell type enhanced" "Detected in some" "Adipocytes: 20.4;Early spermatids: 81.9;Endothelial cells: 32.6;Hepatic stellate cells: 29.3;Late spermatids: 29.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Lineage enriched" "Detected in single" 4 "T-cells: 2.3" "Cell line enhanced" "Detected in some" "BEWO: 23.1;HUVEC TERT2: 44.7;K-562: 16.6;TIME: 82.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB002168 Enhanced NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB002168: AB_564072" "unprognostic (6.53e-2)" "unprognostic (3.36e-1)" "unprognostic (1.63e-2)" "unprognostic (8.46e-2)" "unprognostic (2.96e-2)" "unprognostic (1.47e-1)" "unprognostic (1.35e-1)" "unprognostic (1.36e-1)" "unprognostic (6.97e-2)" "unprognostic (2.56e-1)" "unprognostic (9.40e-2)" "unprognostic (2.36e-1)" "prognostic unfavorable (3.63e-4)" "unprognostic (1.25e-2)" "unprognostic (6.63e-2)" "unprognostic (1.05e-1)" "unprognostic (1.01e-1)" 19.3 6.3 8.4 5.8 6.8 0.8 13.2 5.7 6.7 7.3 3.4 5.9 2.6 9.7 0.4 5.8 8.1 4.7 20.6 5.7 6.1 24.2 4.3 11.2 2.7 9.2 7.7 3.2 2.9 1.2 7.2 4.8 8.6 7.6 1.2 0.8 4.4 1.7 3.9 4.2 6.7 3.7 7.5 62.4 5.4 7.2 11.0 0.6 9.1 3.5 1.2 9.7 7.4 6.0 0.4 0.1 1.3 4.0 0.0 0.0 23.1 0.0 0.0 0.0 0.0 0.3 2.2 0.4 2.1 0.0 0.2 0.7 0.0 0.1 0.0 0.0 0.4 2.2 0.3 6.4 0.6 0.5 10.4 0.1 0.2 0.0 0.0 0.1 44.7 5.1 16.6 3.6 0.0 0.0 0.2 0.5 1.7 0.7 0.1 3.0 0.0 1.8 0.0 0.3 0.5 0.4 0.2 1.4 0.0 0.4 0.1 1.4 82.5 0.2 0.7 0.4 0.1 2.4 8.9 2.2 0.0 7.5 0.0 0.2 0.1 0.1 1.1 0.2 0.7 0.3 1.7 0.9 0.2 0.5 2.3 0.9 0.3 0.2 0.2 0.2 2.1 0.5 8.4 6.8 5.7 6.7 5.7 6.1 9.2 7.7 8.6 7.5 11.0 6.0 20.4 9.6 2.2 0.3 0.7 0.9 0.1 0.1 0.0 0.2 0.2 0.3 3.1 0.0 0.7 0.0 0.0 0.2 0.7 0.1 0.0 1.0 81.9 4.9 0.7 32.6 0.0 0.0 0.2 0.0 0.1 2.9 0.5 3.2 5.7 0.7 29.3 0.7 0.4 0.0 0.2 0.4 0.0 0.6 0.5 29.3 0.9 0.4 0.0 7.5 0.0 0.3 0.0 0.0 0.0 0.8 0.0 1.2 1.5 0.4 0.1 0.2 2.2 0.3 0.0 0.6 2.6 6.9 5.3 0.2 0.6 3.6 1.6 0.9 0.1 0.9 NOTCH3 "CADASIL, CASIL" ENSG00000074181 "Notch receptor 3" Q9UM47 19 15159038-15200995 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Notch signaling pathway, Transcription, Transcription regulation" "Activator, Developmental protein, Receptor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Sertoli cells: 414.2;Skeletal myocytes: 131.6;Smooth muscle cells: 317.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 66.3;MCF7: 66.9;RT4: 41.2;U-87 MG: 45.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005393, HPA044392" Approved Supported "Nucleoplasm,Actin filaments,Cytosol" NA NA 46000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 31: Skin - Epidermis development" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cytosol" "Actin filaments" "CAB005393: AB_2151246, HPA044392: AB_2678926" "unprognostic (4.97e-2)" "unprognostic (3.89e-2)" "unprognostic (7.06e-3)" "prognostic unfavorable (5.92e-4)" "unprognostic (9.20e-2)" "unprognostic (1.73e-2)" "unprognostic (2.72e-1)" "unprognostic (9.04e-2)" "unprognostic (3.90e-3)" "unprognostic (1.23e-1)" "unprognostic (1.19e-1)" "unprognostic (3.13e-1)" "prognostic unfavorable (2.53e-7)" "unprognostic (3.35e-2)" "unprognostic (8.34e-3)" "unprognostic (4.40e-2)" "unprognostic (2.00e-3)" 85.7 5.3 14.8 10.4 12.4 0.2 50.5 11.0 21.3 49.4 7.1 14.8 5.5 39.9 16.9 74.3 35.8 23.5 43.6 9.5 11.3 26.0 3.2 38.3 9.2 12.0 15.2 18.9 10.7 12.6 10.3 59.8 14.3 22.0 4.2 0.5 24.4 16.5 29.7 82.1 14.3 16.9 8.2 15.0 11.6 3.8 15.8 34.1 32.3 25.1 10.4 26.3 55.1 10.0 13.0 8.1 66.3 30.3 9.2 7.3 29.8 10.2 0.4 0.4 0.3 15.6 13.4 0.4 7.7 18.9 0.1 15.1 12.1 0.2 0.6 0.1 3.1 0.4 12.4 3.5 4.5 0.0 1.2 8.4 7.3 15.5 1.6 0.6 0.8 4.6 0.5 0.6 1.2 66.9 15.9 0.1 38.8 11.2 0.0 0.1 3.7 0.3 0.0 41.2 1.9 21.4 0.1 37.8 0.0 19.6 40.3 0.1 0.0 1.9 21.0 0.3 0.1 0.1 0.7 0.0 45.7 0.4 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 14.8 12.4 11.0 21.3 9.5 11.3 12.0 15.2 14.3 8.2 15.8 10.0 39.6 9.6 1.5 5.9 0.4 24.1 7.8 17.8 4.6 0.4 41.5 30.7 60.7 0.0 28.5 16.5 0.0 20.2 1.0 0.0 5.9 14.8 0.5 4.8 13.5 32.0 0.0 0.0 0.6 0.0 3.9 24.2 2.0 11.8 0.0 5.9 4.2 0.0 2.8 0.0 0.3 0.3 6.1 10.4 12.3 0.1 9.0 4.1 17.8 13.1 0.7 0.8 0.0 0.0 0.2 0.9 0.1 11.7 0.0 13.0 0.1 0.0 4.2 0.8 414.2 131.6 317.0 0.9 1.2 72.1 72.2 31.5 2.0 1.2 0.2 36.0 NOTCH4 INT3 ENSG00000204301 "Notch receptor 4" Q99466 6 32194843-32224067 "Human disease related genes, Predicted membrane proteins" "Differentiation, Notch signaling pathway, Transcription, Transcription regulation" "Activator, Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 24.2;breast: 19.8" "Group enriched" "Detected in many" 4 "Adipocytes: 263.8;Endothelial cells: 121.0;Hepatic stellate cells: 188.8" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA 6400000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (2.27e-1)" "unprognostic (2.27e-1)" "unprognostic (6.80e-3)" "unprognostic (9.50e-2)" "unprognostic (1.50e-1)" "unprognostic (1.81e-2)" "unprognostic (3.88e-2)" "unprognostic (3.26e-2)" "unprognostic (1.06e-1)" "unprognostic (1.67e-1)" "unprognostic (1.93e-3)" "unprognostic (2.00e-1)" "prognostic unfavorable (3.84e-4)" "unprognostic (1.31e-2)" "unprognostic (1.66e-1)" "unprognostic (1.56e-1)" "unprognostic (3.13e-1)" 24.2 4.0 0.0 0.5 0.0 0.0 19.8 0.0 0.0 5.8 0.0 3.6 0.5 7.2 3.2 2.7 5.8 0.0 15.8 0.0 0.0 8.5 2.5 18.5 0.4 0.0 0.1 2.8 2.6 0.0 3.0 1.4 0.0 6.0 0.1 0.0 2.6 0.0 5.6 2.8 3.9 0.0 0.0 2.6 3.9 0.9 0.0 0.0 9.6 0.0 0.1 5.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 263.8 0.0 6.1 0.0 6.0 5.2 32.1 9.9 13.6 2.7 2.6 6.6 8.7 0.0 4.2 5.5 4.2 0.4 11.9 0.6 0.0 2.6 46.0 2.6 3.1 121.0 6.0 12.0 0.2 1.1 0.3 4.7 0.0 1.0 0.0 1.8 188.8 2.3 1.7 6.7 0.2 0.8 4.1 9.3 5.2 35.6 7.2 6.8 3.6 10.3 1.6 21.0 0.0 0.0 0.5 0.4 0.3 5.3 0.7 18.0 1.0 0.9 3.1 3.6 0.0 7.8 9.3 5.5 1.9 1.9 1.6 0.3 3.6 3.7 0.9 5.6 NPFFR1 "GPR147, NPFF1R1, OT7T022" ENSG00000148734 "Neuropeptide FF receptor 1" Q9GZQ6 10 70247329-70284004 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 9.5;retina: 3.1" "Cell type enhanced" "Detected in some" "Astrocytes: 6.5;Muller glia cells: 10.4" "Cancer enhanced" "Detected in some" "ovarian cancer: 1.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "basal ganglia: 15.7;hypothalamus: 6.3" "Low region specificity" "Detected in single" HPA037521 Uncertain NA NA "Cluster 11: Basophils - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 5: Muller glia cells - Visual perception" "HPA037521: AB_2675520" "unprognostic (1.73e-3)" "unprognostic (7.29e-4)" "unprognostic (2.12e-1)" "unprognostic (3.50e-2)" "unprognostic (2.07e-1)" "unprognostic (8.66e-3)" "unprognostic (1.37e-1)" "unprognostic (1.48e-1)" "unprognostic (4.14e-2)" "unprognostic (3.51e-1)" "unprognostic (9.62e-2)" "unprognostic (6.78e-2)" "unprognostic (5.84e-5)" "unprognostic (1.37e-1)" "unprognostic (3.93e-2)" "unprognostic (1.78e-3)" "unprognostic (1.04e-1)" 0.2 0.0 1.6 0.4 2.5 0.3 0.1 9.5 1.8 0.1 0.9 0.1 0.1 0.1 0.2 0.0 0.3 0.1 0.0 1.6 2.8 0.0 0.0 0.2 0.6 2.5 2.8 0.1 0.0 0.0 0.1 0.0 2.7 0.1 0.1 3.1 0.0 0.2 0.2 0.1 0.1 0.0 1.8 0.2 0.2 1.0 3.2 0.0 0.0 0.1 0.3 0.1 0.2 2.9 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.1 0.3 0.2 0.0 0.1 0.0 0.7 1.6 2.5 9.5 1.8 1.6 2.8 2.5 2.8 2.7 1.8 3.2 2.9 0.2 0.0 2.0 6.5 0.2 1.7 1.8 0.3 0.0 0.7 0.1 0.3 1.0 1.5 0.0 1.8 0.0 0.2 1.5 0.4 0.0 0.0 0.3 0.6 0.2 0.5 0.0 0.0 0.2 0.2 0.2 0.8 0.0 0.8 2.5 0.1 0.4 0.2 0.1 0.0 1.4 0.1 0.0 0.3 2.8 1.6 0.6 0.8 0.0 0.0 0.4 10.4 1.0 1.0 1.0 0.1 0.1 0.4 0.0 1.1 0.0 0.1 0.1 1.6 0.0 1.7 0.6 0.6 1.2 0.0 2.0 1.1 0.3 0.0 0.2 0.9 NPHP1 "JBTS4, NPH1, SLSN1" ENSG00000144061 "Nephrocystin 1" O15259 2 110122311-110205066 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Differentiation, Spermatogenesis" "Ciliopathy, Disease variant, Joubert syndrome, Leber congenital amaurosis, Nephronophthisis, Senior-Loken syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 36.2" "Cell type enhanced" "Detected in many" "Early spermatids: 148.5;Endometrial ciliated cells: 136.3;Respiratory ciliated cells: 167.4;Spermatocytes: 146.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046093, HPA074071" Approved NA NA "Cluster 24: B-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 49: Ciliated cells - Cilium organization" "HPA046093: AB_2679535, HPA074071: " "unprognostic (2.10e-2)" "unprognostic (1.96e-1)" "unprognostic (1.56e-1)" "unprognostic (1.38e-1)" "unprognostic (5.58e-2)" "unprognostic (4.63e-2)" "unprognostic (1.56e-3)" "unprognostic (4.66e-2)" "unprognostic (1.64e-2)" "unprognostic (1.16e-1)" "unprognostic (1.66e-2)" "unprognostic (1.29e-2)" "unprognostic (1.08e-1)" "unprognostic (2.93e-3)" "unprognostic (3.35e-2)" "unprognostic (1.82e-1)" "unprognostic (8.64e-2)" 3.1 3.7 4.5 1.0 4.7 0.1 4.0 4.0 8.6 4.7 11.1 5.3 1.0 5.4 9.0 1.3 17.1 3.3 4.8 4.6 5.2 8.0 0.8 4.3 0.9 5.4 5.8 4.5 3.2 17.0 11.7 1.3 5.0 4.4 1.7 10.8 2.5 4.7 36.2 1.7 1.9 4.6 4.6 1.9 3.6 24.9 5.5 1.1 7.4 10.8 0.6 4.1 2.7 4.6 9.8 3.1 5.9 4.3 3.3 7.9 1.3 2.4 7.9 8.5 8.4 3.1 7.1 0.5 6.0 5.8 7.8 4.7 2.8 7.5 10.0 1.7 3.9 0.2 1.9 2.1 4.5 1.4 0.0 5.2 4.4 12.7 3.6 12.0 4.7 1.9 0.1 0.8 4.9 2.0 1.0 2.1 2.8 0.2 4.9 0.2 6.5 0.3 14.5 0.8 3.0 3.1 3.2 4.2 9.2 2.8 5.1 1.0 3.2 4.9 4.2 5.0 7.7 2.4 2.9 0.7 13.9 0.2 3.3 0.3 0.0 0.0 0.3 0.1 0.5 0.8 0.2 0.1 0.3 1.5 0.5 0.3 0.2 1.1 0.0 0.0 0.0 0.1 4.5 4.7 4.0 8.6 4.6 5.2 5.4 5.8 5.0 4.6 5.5 4.6 8.3 6.4 8.9 31.6 1.6 5.2 8.7 18.1 2.8 11.8 5.3 6.6 14.3 8.6 23.3 9.2 47.9 1.9 0.3 0.8 19.6 15.6 148.5 136.3 15.8 7.0 0.0 0.0 29.1 4.9 0.5 8.1 0.0 17.0 0.0 13.4 9.3 2.7 1.4 21.9 15.0 0.9 18.3 0.8 3.1 65.2 7.5 1.4 7.2 4.7 0.0 12.3 0.0 12.1 11.5 6.4 1.3 9.8 0.1 3.1 0.2 35.9 167.4 69.1 13.1 14.3 10.3 146.3 24.9 1.0 4.0 0.3 1.3 9.6 1.7 5.8 NPM2 ENSG00000158806 "Nucleophosmin/nucleoplasmin 2" Q86SE8 8 22024125-22036897 "Predicted intracellular proteins" Fertilization "Chaperone, Chromatin regulator, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 40.0;parathyroid gland: 39.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 29.4;Cone photoreceptor cells: 20.9;Excitatory neurons: 21.3;Inhibitory neurons: 21.9" "Cancer enhanced" "Detected in many" "thyroid cancer: 10.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "eosinophil: 1.5" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HaCaT: 17.7;HEL: 14.5;Hep G2: 32.4;JURKAT: 9.5;THP-1: 11.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA041070 Enhanced Approved Nucleoplasm,Nucleoli NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 62: Horizontal cells - Visual perception" "Nucleoplasm, Nucleoli" "HPA041070: AB_2677285" "unprognostic (1.40e-2)" "unprognostic (3.30e-2)" "unprognostic (3.11e-2)" "unprognostic (2.49e-2)" "unprognostic (1.55e-1)" "unprognostic (2.06e-1)" "unprognostic (1.61e-1)" "unprognostic (3.03e-2)" "unprognostic (5.30e-3)" "unprognostic (1.01e-1)" "prognostic favorable (9.02e-4)" "unprognostic (2.23e-1)" "prognostic favorable (3.18e-6)" "unprognostic (8.05e-3)" "unprognostic (2.89e-1)" "unprognostic (1.42e-1)" "unprognostic (1.30e-1)" 0.6 18.4 11.0 0.1 16.9 1.2 2.1 7.4 40.0 4.9 2.2 1.1 2.2 5.0 0.9 1.0 3.2 1.9 2.3 12.4 9.2 6.6 1.6 1.8 0.6 7.5 7.6 1.5 11.0 39.2 18.5 0.5 10.0 6.6 1.0 5.7 2.7 1.4 0.3 2.2 1.2 3.6 2.3 12.5 1.9 5.1 7.1 2.9 25.3 0.3 0.4 2.0 2.3 13.5 3.9 0.5 0.2 0.2 0.9 0.0 1.5 0.5 0.5 2.4 4.9 1.6 3.6 0.0 1.1 0.0 0.2 17.7 0.5 0.0 1.4 0.1 0.5 14.5 1.0 32.4 3.1 1.9 1.3 0.5 2.3 0.0 0.3 3.7 0.0 9.5 0.5 0.0 0.1 0.0 0.2 3.9 0.7 6.4 0.4 0.3 1.4 0.8 5.6 0.1 3.8 0.2 0.0 0.1 4.6 0.0 0.7 11.2 0.0 0.0 0.3 0.6 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.5 0.2 0.0 0.7 0.0 0.2 0.6 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 11.0 16.9 7.4 40.0 12.4 9.2 7.5 7.6 10.0 2.3 7.1 13.5 0.1 0.0 1.1 1.0 0.7 0.1 9.7 3.7 0.6 29.4 3.1 5.2 2.1 5.7 8.8 0.0 20.9 0.1 0.5 0.6 3.9 9.4 15.1 1.1 0.3 0.6 11.4 0.4 21.3 8.0 0.2 1.7 1.5 1.1 0.0 1.4 2.5 0.5 4.6 6.7 21.9 2.1 2.0 0.0 0.3 14.4 0.6 0.9 10.6 1.9 1.0 0.9 0.0 2.5 1.6 4.3 0.8 0.4 0.6 3.4 0.5 14.6 7.7 4.2 0.0 0.4 1.6 0.5 0.9 1.1 1.1 0.3 2.7 7.6 1.2 5.8 NR3C1 "GR, GRL" ENSG00000113580 "Nuclear receptor subfamily 3 group C member 1" P04150 5 143277931-143435512 "Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Apoptosis, Cell cycle, Cell division, Chromosome partition, Mitosis, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Receptor, RNA-binding" "Disease variant, FDA approved drug targets, Pseudohermaphroditism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 411.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004248, CAB010435" Supported Supported Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nucleoplasm, Cytosol" Mitochondria "CAB010435: AB_2155784, HPA004248: AB_1078976" "unprognostic (1.38e-1)" "unprognostic (1.93e-1)" "unprognostic (1.17e-1)" "prognostic unfavorable (3.64e-5)" "unprognostic (1.43e-2)" "unprognostic (2.74e-1)" "unprognostic (4.19e-1)" "unprognostic (1.39e-1)" "unprognostic (2.46e-2)" "unprognostic (3.87e-2)" "unprognostic (2.15e-1)" "unprognostic (6.85e-2)" "prognostic unfavorable (1.72e-6)" "unprognostic (9.06e-3)" "unprognostic (1.02e-1)" "unprognostic (2.43e-3)" "unprognostic (2.45e-2)" 35.3 11.8 15.2 22.6 18.1 49.4 25.5 34.0 24.7 19.7 18.2 13.7 19.2 18.8 13.6 25.7 18.8 21.1 24.2 14.9 25.0 19.2 39.8 31.9 25.6 18.1 14.9 21.1 14.7 33.8 16.2 46.9 16.1 19.7 14.5 9.5 16.1 20.0 45.0 20.4 18.0 23.8 15.0 24.5 16.0 11.1 21.6 40.0 25.6 40.1 27.3 18.2 16.0 28.5 30.4 60.6 4.4 0.1 38.2 42.3 5.2 46.5 55.3 39.3 45.1 4.5 39.7 26.8 20.8 68.6 46.0 28.1 0.3 36.6 48.3 15.2 21.0 6.9 77.0 13.5 35.7 28.1 20.6 30.8 46.3 64.7 62.5 49.0 15.0 12.1 10.3 98.8 35.1 10.9 16.7 20.0 11.9 5.1 13.0 6.0 41.4 58.0 11.5 2.1 8.0 6.1 81.3 11.7 19.4 4.9 5.3 39.8 35.8 94.7 18.7 45.7 35.9 20.1 19.7 41.5 49.7 28.5 33.6 67.4 21.3 38.9 18.3 24.2 15.1 15.9 18.6 17.9 28.5 22.3 17.8 17.2 68.4 23.1 23.6 25.9 12.8 17.3 15.2 18.1 34.0 24.7 14.9 25.0 18.1 14.9 16.1 15.0 21.6 28.5 152.3 67.3 69.1 71.2 134.1 58.8 35.9 37.9 79.6 13.1 39.0 55.8 43.4 57.2 41.2 25.8 16.7 48.9 158.3 22.9 17.6 30.8 165.6 8.1 30.1 82.3 28.1 55.9 411.4 33.3 39.5 112.2 23.9 10.4 89.3 7.5 63.5 193.9 53.2 37.0 169.5 4.1 10.2 66.3 99.2 144.1 63.0 97.4 53.4 241.7 87.6 34.6 83.4 240.3 237.5 35.9 17.9 71.5 115.1 46.2 25.3 67.9 37.9 65.0 151.2 181.9 105.0 24.5 40.1 57.4 56.3 36.5 204.5 12.6 12.9 14.3 NRN1 NRN ENSG00000124785 "Neuritin 1" Q9NPD7 6 5997999-6007605 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 98.9;parathyroid gland: 81.0" "Cell type enhanced" "Detected in many" "Adipocytes: 262.9;Endothelial cells: 115.3;Excitatory neurons: 71.9;Extravillous trophoblasts: 64.7;Hepatic stellate cells: 160.3" "Cancer enhanced" "Detected in all" "glioma: 38.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "MAIT T-cell: 2.6;neutrophil: 2.2" "Group enriched" "Detected in many" 7 "granulocytes: 2.2;T-cells: 2.6" "Cell line enhanced" "Detected in many" "ASC diff: 140.0;ASC TERT1: 107.6;fHDF/TERT166: 147.5;JURKAT: 134.8;REH: 196.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 23000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 14: REH - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (6.24e-2)" "unprognostic (2.47e-2)" "unprognostic (1.35e-2)" "unprognostic (1.22e-1)" "unprognostic (1.26e-2)" "unprognostic (5.57e-2)" "unprognostic (4.70e-3)" "unprognostic (2.02e-2)" "unprognostic (1.03e-1)" "unprognostic (1.49e-1)" "unprognostic (1.67e-2)" "unprognostic (3.35e-1)" "prognostic unfavorable (4.79e-5)" "unprognostic (1.26e-1)" "unprognostic (2.04e-1)" "unprognostic (2.90e-1)" "unprognostic (4.37e-3)" 66.4 5.1 49.1 6.4 44.9 0.5 64.2 46.0 80.8 16.2 17.0 21.3 3.7 9.4 4.0 8.2 13.6 11.2 19.7 98.9 27.7 8.2 4.4 15.6 9.6 30.4 29.9 4.7 2.9 81.0 12.3 42.1 32.5 10.1 4.7 23.4 8.7 7.4 17.3 18.8 10.8 10.5 22.1 15.7 10.3 0.6 60.1 3.6 9.4 16.1 3.5 13.8 17.0 45.9 16.7 0.6 1.4 0.1 140.0 107.6 19.1 2.6 0.0 11.8 16.1 0.2 0.1 0.0 2.5 147.5 25.0 0.5 43.3 0.0 11.4 26.1 21.2 13.7 0.0 0.0 0.0 58.0 43.7 17.3 0.0 10.5 0.0 0.1 57.4 134.8 0.2 0.6 42.5 0.1 89.7 2.6 0.1 0.0 0.0 196.3 47.7 0.4 0.2 0.2 24.9 9.2 0.0 0.8 13.9 0.2 0.4 16.4 12.1 56.4 1.6 21.4 36.5 0.1 2.2 0.9 85.8 0.2 8.9 0.0 0.1 0.0 0.1 0.1 2.6 0.3 0.2 0.3 0.0 0.0 0.0 0.0 2.2 0.0 0.1 0.2 0.0 0.1 49.1 44.9 46.0 80.8 98.9 27.7 30.4 29.9 32.5 22.1 60.1 45.9 262.9 0.0 1.3 7.2 1.6 10.5 0.1 0.0 1.2 6.7 1.4 2.4 2.5 1.5 0.0 0.0 2.1 1.5 1.0 0.0 0.0 0.1 0.1 0.0 0.1 115.3 0.0 0.0 71.9 0.5 64.7 15.9 0.0 0.1 0.0 0.0 160.3 0.9 1.8 3.3 3.0 0.0 0.0 4.1 21.5 0.4 0.9 1.4 16.0 8.4 0.5 4.5 0.0 13.6 8.3 0.2 0.0 0.0 1.4 0.4 0.0 0.0 0.0 20.2 0.0 4.4 18.3 0.4 0.3 0.6 11.2 1.4 1.9 0.1 0.0 0.7 NSRP1 "CCDC55, DKFZP434K1421, NSrp70" ENSG00000126653 "Nuclear speckle splicing regulatory protein 1" Q9H0G5 17 30115521-30186475 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015593, HPA015603" Enhanced Supported Nucleoplasm NA NA "Cluster 6: Non-specific - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "HPA015593: AB_2072217, HPA015603: AB_1846157" "unprognostic (3.96e-1)" "unprognostic (2.16e-2)" "unprognostic (5.45e-2)" "unprognostic (1.69e-1)" "unprognostic (1.34e-1)" "unprognostic (1.89e-1)" "unprognostic (7.76e-2)" "unprognostic (1.83e-1)" "unprognostic (5.93e-3)" "unprognostic (6.12e-2)" "unprognostic (2.21e-1)" "unprognostic (3.08e-2)" "unprognostic (1.31e-3)" "unprognostic (2.02e-1)" "unprognostic (1.98e-1)" "unprognostic (1.34e-1)" "unprognostic (2.43e-1)" 23.1 18.8 25.0 18.8 28.4 25.0 21.9 34.0 34.4 18.6 32.5 25.0 16.8 22.9 22.5 19.5 19.6 19.6 25.8 21.7 28.5 21.4 20.2 18.8 22.3 29.8 25.5 22.8 20.3 24.2 17.9 22.0 27.9 20.5 18.3 19.5 18.0 17.9 25.2 25.0 17.9 21.1 25.0 19.4 19.1 19.3 26.9 17.6 25.5 20.8 19.9 21.1 18.0 34.7 30.9 27.3 26.3 21.0 35.0 33.0 18.6 41.8 42.6 31.4 33.5 28.3 19.6 56.1 32.6 39.8 38.5 44.4 41.1 32.2 50.8 13.5 55.7 25.6 43.8 21.1 56.5 40.0 29.8 38.3 41.5 50.1 64.6 36.5 29.7 20.3 41.0 35.6 43.8 22.1 26.9 39.0 17.4 33.8 22.0 30.8 43.3 37.8 32.5 32.9 24.8 21.6 32.1 84.2 38.6 26.4 44.1 44.3 32.4 37.7 26.7 40.0 67.1 25.8 36.9 44.1 46.5 35.5 44.1 66.1 39.7 33.1 32.2 38.2 36.0 62.1 35.8 32.1 21.5 57.9 34.6 31.5 59.5 32.8 44.4 62.4 35.6 14.5 25.0 28.4 34.0 34.4 21.7 28.5 29.8 25.5 27.9 25.0 26.9 34.7 97.5 76.9 91.0 49.0 59.2 67.6 95.9 124.0 88.8 62.6 51.4 64.1 147.3 72.9 80.6 84.6 35.5 58.3 54.0 57.5 97.8 71.7 259.2 79.2 89.6 91.9 31.3 68.0 30.6 75.2 69.5 76.3 37.8 76.6 83.4 43.6 94.9 143.7 53.6 74.0 41.9 65.1 59.0 63.1 46.5 137.0 77.0 52.3 49.8 69.3 70.6 78.7 63.8 52.8 88.5 71.1 54.1 71.5 48.2 75.8 57.9 90.6 84.9 56.8 72.3 113.1 97.1 186.9 105.8 40.7 52.0 110.8 52.5 56.1 54.3 63.2 NSUN4 "MGC22960, SHTAP" ENSG00000117481 "NOP2/Sun RNA methyltransferase 4" Q96CB9 1 46340177-46365152 "Metabolic proteins, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Methyltransferase, RNA-binding, rRNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 15 "testis: 89.0" "Group enriched" "Detected in many" 11 "Early spermatids: 144.5;Late spermatids: 513.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" HPA028489 Approved NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 83: Testis - Spermatogenesis" "Cluster 25: RPMI-8226 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "HPA028489: AB_10601444" "unprognostic (3.28e-2)" "unprognostic (1.86e-1)" "unprognostic (1.33e-2)" "unprognostic (5.53e-2)" "prognostic favorable (8.99e-4)" "unprognostic (2.02e-2)" "prognostic unfavorable (1.97e-5)" "unprognostic (5.50e-2)" "unprognostic (1.34e-2)" "unprognostic (6.79e-2)" "unprognostic (1.22e-1)" "unprognostic (2.19e-1)" "unprognostic (1.22e-3)" "unprognostic (2.65e-2)" "unprognostic (1.87e-1)" "unprognostic (1.13e-3)" "unprognostic (2.28e-1)" 3.6 5.2 0.7 2.8 0.9 5.9 3.0 1.8 1.5 2.7 1.6 2.6 2.8 2.7 1.2 3.9 2.6 3.6 3.8 0.7 1.2 3.6 4.4 3.0 2.7 1.4 1.7 3.6 3.0 3.3 3.6 3.5 1.5 3.6 3.0 2.3 3.5 2.3 3.7 3.3 2.7 3.0 0.3 3.4 2.7 89.0 1.2 3.1 3.3 3.6 4.0 4.4 3.1 1.2 4.1 8.5 6.4 7.6 7.6 5.6 9.2 4.2 5.3 8.5 9.2 10.2 3.6 10.4 11.4 6.3 11.9 6.1 5.7 9.3 6.4 12.4 9.8 10.2 9.4 13.9 8.9 7.9 7.5 7.5 9.4 11.8 13.1 3.4 9.5 8.1 15.9 10.7 8.8 12.8 6.8 4.3 7.6 6.0 3.9 9.3 4.2 14.0 14.7 13.4 9.7 3.4 6.7 8.3 8.6 6.4 5.4 9.9 7.2 5.7 6.2 4.2 5.1 5.9 5.5 9.1 3.2 9.9 6.6 2.3 7.6 8.3 3.4 5.1 4.7 7.8 3.6 4.4 7.1 5.9 4.2 3.0 20.5 4.4 4.0 8.7 2.0 3.7 0.7 0.9 1.8 1.5 0.7 1.2 1.4 1.7 1.5 0.3 1.2 1.2 8.1 19.2 17.5 10.4 13.7 5.6 13.0 8.1 13.6 9.1 9.5 8.1 14.6 17.2 12.4 9.2 8.4 11.1 11.5 5.4 1.9 9.1 144.5 10.4 9.4 13.3 7.8 17.7 13.8 6.9 11.3 9.4 14.8 12.4 29.8 9.4 8.9 12.6 9.3 5.0 14.7 9.0 4.1 13.1 8.6 513.8 12.5 14.1 3.6 8.4 9.2 5.7 4.1 11.1 12.5 9.0 5.8 10.9 12.5 16.0 5.7 11.8 8.4 11.5 0.0 11.0 9.2 7.6 11.4 13.1 5.8 15.2 8.8 11.3 9.0 15.2 NSUN7 FLJ14001 ENSG00000179299 "NOP2/Sun RNA methyltransferase family member 7" Q8NE18 4 40749925-40811184 "Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 16.5" "Cell type enhanced" "Detected in many" "Early spermatids: 47.5;Late spermatids: 75.6;Respiratory ciliated cells: 36.4;Spermatocytes: 38.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 6 "neutrophil: 2.7" "Lineage enriched" "Detected in single" 6 "granulocytes: 2.7" "Cell line enhanced" "Detected in some" "A-431: 2.6;CAPAN-2: 5.5;Karpas-707: 4.0;MCF7: 2.6;SuSa: 3.0;T-47d: 3.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA020653 Uncertain Approved Vesicles NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "HPA020653: AB_1848710" "unprognostic (2.32e-1)" "unprognostic (4.22e-1)" "unprognostic (4.77e-2)" "unprognostic (1.50e-1)" "unprognostic (2.79e-2)" "unprognostic (1.47e-1)" "unprognostic (1.63e-1)" "unprognostic (4.01e-3)" "unprognostic (4.37e-2)" "unprognostic (3.06e-1)" "unprognostic (2.24e-1)" "unprognostic (8.42e-2)" "prognostic favorable (2.76e-8)" "unprognostic (3.69e-2)" "unprognostic (1.15e-1)" "unprognostic (1.12e-1)" "unprognostic (1.04e-2)" 0.6 0.9 0.6 1.0 0.6 0.6 3.8 0.4 0.4 2.5 7.2 2.8 1.7 2.2 2.7 1.8 6.8 1.2 2.1 0.5 1.5 4.7 0.4 3.3 0.3 1.8 2.4 2.3 7.2 3.3 3.6 1.3 1.5 4.5 2.4 0.7 4.8 1.5 0.0 1.5 2.1 1.2 1.2 2.7 3.2 16.5 2.0 0.3 4.7 0.2 0.3 1.3 1.2 0.8 2.6 0.1 1.2 0.0 0.0 0.0 1.7 0.0 0.2 0.1 0.1 1.0 5.5 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 2.6 0.1 0.0 1.4 0.0 0.3 0.1 0.0 0.0 2.4 0.7 0.6 1.5 0.3 1.7 0.0 3.0 3.9 0.0 0.1 0.0 2.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.4 0.4 0.5 1.5 1.8 2.4 1.5 1.2 2.0 0.8 0.1 9.6 7.8 3.6 4.3 1.1 3.1 1.5 2.2 0.1 8.6 7.1 3.5 0.0 10.5 9.2 0.0 9.2 0.1 2.7 9.8 5.8 47.5 20.7 0.9 0.6 8.3 0.4 0.7 5.4 3.6 1.2 4.6 5.4 0.0 8.5 0.7 0.2 3.8 0.0 0.9 7.1 4.1 0.8 0.4 75.6 1.5 2.2 0.0 8.4 1.0 2.1 0.0 18.1 1.3 4.7 2.7 0.0 0.3 4.5 2.2 5.5 36.4 0.1 0.0 0.4 0.8 38.9 11.4 8.2 1.0 4.5 0.7 3.4 7.7 5.7 NT5DC4 ENSG00000144130 "5'-nucleotidase domain containing 4" Q86YG4 2 112721486-112742879 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "testis: 2.2" "Group enriched" "Detected in some" 11 "Early spermatids: 20.0;Late spermatids: 6.4" "Cancer enhanced" "Detected in single" "testis cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "K-562: 16.1" "Not detected" "Not detected" HPA046856 Uncertain NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 1: K-562 - Erythropoiesis" "Cluster 29: Early spermatids - Spermatogenesis" "HPA046856: AB_2679841" "unprognostic (2.49e-2)" "unprognostic (1.16e-1)" "unprognostic (1.46e-2)" "unprognostic (1.34e-2)" "unprognostic (2.20e-4)" "unprognostic (2.26e-1)" "unprognostic (3.66e-2)" "unprognostic (2.40e-1)" "unprognostic (1.19e-1)" "unprognostic (5.38e-4)" "unprognostic (1.38e-1)" "unprognostic (2.66e-1)" "unprognostic (1.60e-4)" "unprognostic (9.02e-2)" "unprognostic (1.33e-1)" "unprognostic (1.11e-1)" "unprognostic (1.78e-4)" 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 2.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.2 0.1 0.1 0.0 1.0 0.3 0.0 0.0 0.0 0.2 0.0 0.4 0.2 0.6 0.0 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.1 1.2 0.0 0.0 0.1 2.2 0.0 1.2 0.1 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.3 0.1 0.1 0.0 0.2 0.5 0.0 0.2 0.1 0.1 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 20.0 0.3 0.1 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 1.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.1 NTAN1 ENSG00000157045 "N-terminal asparagine amidase" Q96AB6 16 15037854-15056079 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 17.5" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NB-4: 18.5;REH: 9.2;U-266/84: 10.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051418 Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 24: NB-4 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "Golgi apparatus" "HPA051418: " "unprognostic (2.21e-2)" "unprognostic (2.31e-1)" "unprognostic (1.80e-1)" "unprognostic (1.47e-1)" "prognostic unfavorable (6.69e-4)" "unprognostic (1.87e-2)" "unprognostic (9.16e-2)" "unprognostic (8.11e-3)" "unprognostic (2.79e-1)" "unprognostic (1.75e-1)" "unprognostic (5.05e-2)" "unprognostic (1.65e-1)" "unprognostic (9.30e-3)" "prognostic unfavorable (9.07e-4)" "unprognostic (4.35e-1)" "unprognostic (2.12e-2)" "unprognostic (1.10e-1)" 38.6 10.2 3.6 0.5 3.9 2.2 28.1 3.8 8.9 25.3 2.1 30.3 0.1 20.7 1.4 19.4 18.8 1.2 19.3 3.4 3.7 15.9 15.2 21.6 0.7 3.8 4.1 19.7 11.0 0.5 6.5 0.4 4.1 20.2 0.3 1.3 15.8 0.4 24.5 21.6 15.6 0.8 2.9 20.5 17.9 20.3 3.7 0.8 13.5 0.6 0.4 27.8 21.8 3.5 3.6 0.0 1.8 0.7 1.2 0.6 0.6 6.2 2.6 1.0 2.8 0.0 0.0 3.2 2.5 4.7 1.7 0.1 0.9 0.7 0.9 5.0 5.9 0.3 0.0 0.0 1.1 1.7 4.3 0.8 0.4 3.4 1.5 1.5 1.3 2.6 0.5 3.2 0.9 0.3 5.3 18.5 1.1 0.0 0.2 9.2 0.1 1.3 1.2 0.0 0.7 2.1 0.0 0.1 1.5 0.4 0.0 0.6 4.1 1.1 3.8 1.1 1.1 4.2 10.1 2.5 1.5 1.3 2.2 4.9 1.3 17.5 2.8 1.7 3.0 4.2 3.4 2.6 1.9 3.8 3.9 1.3 1.6 3.8 2.0 5.7 5.9 3.1 3.6 3.9 3.8 8.9 3.4 3.7 3.8 4.1 4.1 2.9 3.7 3.5 79.7 3.2 3.9 7.8 24.7 33.6 16.4 24.1 7.4 6.1 20.2 33.4 3.2 12.8 13.8 18.4 10.4 77.4 30.4 25.1 45.0 49.3 48.9 8.8 29.3 55.0 6.7 25.3 12.6 23.6 23.8 51.3 8.2 12.7 8.8 22.0 62.8 23.0 116.6 25.2 15.6 7.2 30.5 75.0 48.3 32.4 83.0 53.9 58.7 12.2 46.0 15.2 37.0 3.0 6.6 56.9 14.6 75.2 37.6 21.2 9.6 38.6 6.0 9.4 39.5 20.8 52.3 33.3 30.7 16.0 21.7 56.9 25.6 23.5 13.5 23.9 NUAK2 "FLJ90349, SNARK" ENSG00000163545 "NUAK family kinase 2" Q9H093 1 205302063-205321745 "Enzymes, Metabolic proteins, Predicted membrane proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 56.7;vagina: 45.3" "Cell type enhanced" "Detected in many" "Ductal cells: 46.9;Endometrial ciliated cells: 45.3;Glandular and luminal cells: 52.4;Intestinal goblet cells: 43.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 120.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 44.1;RPMI-8226: 36.1;RPTEC TERT1: 40.9;SuSa: 45.6" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA008958 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Cytosol" "HPA008958: AB_1080040" "unprognostic (2.24e-2)" "unprognostic (6.33e-2)" "unprognostic (1.17e-1)" "prognostic unfavorable (3.01e-7)" "unprognostic (8.24e-3)" "unprognostic (1.58e-2)" "unprognostic (3.00e-2)" "unprognostic (1.08e-2)" "unprognostic (1.74e-1)" "unprognostic (9.19e-2)" "prognostic favorable (7.94e-6)" "unprognostic (3.71e-2)" "unprognostic (3.17e-2)" "unprognostic (4.90e-2)" "unprognostic (5.80e-2)" "unprognostic (4.54e-2)" "unprognostic (1.61e-1)" 2.1 3.7 1.3 7.7 1.9 11.4 0.9 4.6 1.7 31.0 3.2 8.0 16.5 1.6 1.3 56.7 4.0 1.7 1.2 1.2 1.3 28.2 5.1 10.3 11.5 2.1 1.8 1.3 16.0 0.8 3.0 4.4 2.0 1.9 8.8 0.5 15.1 1.6 0.7 22.4 12.5 1.2 1.4 13.1 2.5 3.7 2.2 3.9 16.1 1.1 8.0 3.1 45.3 4.1 4.3 23.1 13.7 0.6 0.3 0.6 44.1 5.5 5.7 14.7 5.9 24.4 0.8 7.0 3.2 1.5 24.1 8.3 3.2 8.3 6.3 0.0 0.4 0.0 1.4 4.2 9.3 0.0 0.1 2.6 6.1 8.6 5.0 3.3 0.7 0.0 0.9 1.7 2.8 1.0 0.0 0.1 8.9 3.1 0.7 0.0 1.0 36.1 40.9 0.1 2.1 0.2 1.6 6.5 0.7 45.6 6.6 0.1 1.7 5.3 2.5 0.6 8.7 12.1 2.0 4.4 0.8 0.0 2.1 11.2 16.5 40.1 10.3 11.8 7.6 37.9 12.7 12.3 10.4 39.3 27.9 21.9 120.4 17.5 13.1 4.1 8.1 17.4 1.3 1.9 4.6 1.7 1.2 1.3 2.1 1.8 2.0 1.4 2.2 4.1 2.0 6.4 6.8 0.3 28.0 1.1 3.2 3.7 13.1 1.1 1.9 2.2 2.7 20.0 2.9 33.1 0.0 9.2 7.1 34.9 5.9 46.9 2.0 45.3 7.5 5.9 10.8 2.7 0.1 1.8 29.1 3.7 7.7 52.4 0.0 2.4 0.7 2.6 4.7 0.0 0.4 43.0 18.3 12.3 11.1 2.1 0.0 8.9 7.2 3.7 38.5 1.3 18.6 0.5 3.5 6.9 7.8 0.0 18.5 2.5 18.3 17.2 7.7 0.5 6.6 2.4 5.5 0.9 1.1 21.5 5.4 4.1 5.7 0.5 22.0 0.5 NUDT10 "DIPP3a, hDIPP3alpha" ENSG00000122824 "Nudix hydrolase 10" Q8NFP7 X 51332231-51337525 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 26.3" "Group enriched" "Detected in many" 5 "Hepatic stellate cells: 60.3;Peritubular cells: 29.0" "Group enriched" "Detected in many" 6 "glioma: 5.0;prostate cancer: 5.4;testis cancer: 7.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 7.5;HAP1: 14.2;HEK 293: 10.5;NTERA-2: 25.8;SH-SY5Y: 5.6;U-2 OS: 12.7" "HPA047027, HPA057684" Approved Approved Cytosol NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "HPA047027: AB_2679907, HPA057684: AB_2683501" "unprognostic (2.61e-2)" "unprognostic (1.12e-2)" "unprognostic (7.40e-3)" "unprognostic (7.84e-2)" "unprognostic (1.82e-1)" "unprognostic (2.51e-2)" "unprognostic (1.16e-1)" "unprognostic (2.06e-1)" "unprognostic (2.54e-2)" "unprognostic (1.11e-1)" "unprognostic (2.49e-2)" "unprognostic (1.27e-1)" "unprognostic (1.51e-3)" "unprognostic (1.80e-3)" "unprognostic (1.04e-2)" "unprognostic (1.12e-2)" "unprognostic (5.04e-5)" 0.6 1.6 11.2 0.8 9.8 1.5 0.8 3.8 9.8 6.2 2.3 3.1 0.5 5.3 16.1 1.0 3.6 1.4 1.0 9.2 10.0 3.9 1.3 0.3 0.3 5.0 7.1 16.9 0.3 0.0 2.1 0.0 7.1 14.9 0.7 1.5 0.5 14.6 0.1 0.4 1.0 4.1 4.1 3.4 1.2 26.3 11.9 0.4 0.6 0.2 0.3 3.9 3.6 9.3 0.0 0.0 7.5 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 1.2 0.0 14.2 0.6 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 25.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 12.7 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 11.2 9.8 3.8 9.8 9.2 10.0 5.0 7.1 7.1 4.1 11.9 9.3 0.2 0.0 1.3 0.7 0.2 1.0 4.9 0.6 1.8 0.5 0.1 1.5 0.2 0.0 0.6 0.0 0.0 0.7 0.4 0.0 0.0 0.0 1.5 0.7 3.5 2.5 0.0 0.8 5.0 0.0 1.0 3.1 0.0 0.1 0.0 5.0 60.3 0.3 0.2 0.0 1.9 0.0 0.0 1.9 0.4 6.2 5.9 0.1 1.8 1.0 0.0 1.7 0.0 3.5 0.6 0.0 0.0 29.0 1.4 2.8 0.0 0.1 0.0 0.5 0.0 1.5 1.9 3.8 7.8 0.4 0.1 0.4 0.2 0.9 0.0 0.2 NUDT11 "DIPP3b, FLJ10628, hDIPP3beta" ENSG00000196368 "Nudix hydrolase 11" Q96G61 X 51490011-51496592 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.3;testis: 36.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 15.3;Late spermatids: 17.1;Peritubular cells: 20.7;Spermatocytes: 14.6;Spermatogonia: 20.3" "Group enriched" "Detected in many" 4 "glioma: 12.1;prostate cancer: 10.6;testis cancer: 17.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HAP1: 69.3;NTERA-2: 42.9" "Low region specificity" "Detected in many" "HPA047027, HPA057684" Approved Approved Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 78: Testis - Spermatogenesis" "Cluster 5: NTERA-2 - Transcription" "Cluster 36: Stromal cells - Cell proliferation" Cytosol "HPA047027: AB_2679907, HPA057684: AB_2683501" "unprognostic (2.01e-1)" "unprognostic (2.57e-1)" "unprognostic (8.21e-2)" "unprognostic (1.93e-3)" "unprognostic (6.61e-2)" "unprognostic (1.13e-3)" "unprognostic (5.52e-3)" "unprognostic (1.25e-1)" "unprognostic (2.25e-2)" "unprognostic (2.18e-1)" "unprognostic (8.41e-2)" "unprognostic (1.33e-1)" "unprognostic (7.80e-12)" "unprognostic (4.34e-4)" "unprognostic (1.17e-2)" "unprognostic (2.78e-1)" "unprognostic (3.94e-4)" 1.0 4.6 11.9 0.9 13.7 1.4 2.1 4.5 14.7 4.0 2.1 2.9 1.1 5.1 3.5 1.3 2.0 1.6 0.5 13.4 20.0 0.5 0.1 0.5 0.6 5.6 7.2 8.9 4.9 0.2 4.3 0.0 8.4 9.1 0.8 2.2 0.7 10.4 0.1 1.2 1.0 4.4 5.6 0.3 1.1 36.2 23.3 2.6 0.6 0.5 0.6 1.9 2.4 7.7 0.0 1.0 20.6 0.0 17.5 22.0 0.1 9.8 2.7 0.5 0.5 0.0 0.0 0.0 0.5 11.9 11.4 1.5 69.3 23.9 0.3 0.0 4.7 0.0 0.0 0.0 8.2 0.0 4.6 13.5 9.3 6.2 22.4 3.9 16.4 21.6 0.1 0.0 19.6 0.5 27.6 0.1 42.9 0.0 17.5 0.0 14.4 0.0 4.3 0.0 0.0 13.4 4.2 0.0 4.0 10.2 0.0 0.1 9.6 4.8 22.4 1.4 0.0 9.0 4.5 15.2 3.1 0.0 1.9 0.0 0.0 0.0 1.2 0.0 0.5 0.1 0.3 0.6 0.1 0.1 0.0 0.9 0.0 0.7 0.1 0.0 0.0 0.3 11.9 13.7 4.5 14.7 13.4 20.0 5.6 7.2 8.4 5.6 23.3 7.7 0.4 0.0 0.0 0.3 0.3 15.3 6.4 12.8 12.0 1.6 0.5 3.9 0.6 0.0 1.6 0.0 0.0 0.3 3.5 0.0 0.0 0.2 11.3 0.5 9.0 0.9 0.0 1.3 6.3 1.5 1.0 7.7 0.0 0.3 0.0 3.4 0.4 0.0 0.1 0.0 3.8 0.0 0.0 0.3 3.8 17.1 8.7 0.6 5.4 2.8 0.0 1.4 3.1 4.0 0.6 1.4 0.0 20.7 0.3 10.4 0.0 0.2 0.2 0.2 0.0 3.0 5.3 14.6 20.3 1.6 9.1 0.3 0.8 7.5 0.0 1.3 NUDT15 "FLJ10956, MTH2" ENSG00000136159 "Nudix hydrolase 15" Q9NV35 13 48037726-48047221 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 79.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038968, HPA038969" Approved Supported Nucleoplasm Yes No "Cluster 22: NK-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "HPA038968: AB_10697402, HPA038969: AB_2676295" "unprognostic (9.48e-2)" "unprognostic (5.91e-3)" "unprognostic (2.64e-2)" "unprognostic (9.00e-3)" "unprognostic (4.99e-2)" "unprognostic (2.50e-3)" "unprognostic (2.29e-2)" "unprognostic (7.47e-3)" "prognostic unfavorable (1.25e-5)" "unprognostic (1.04e-1)" "unprognostic (8.50e-2)" "unprognostic (3.69e-1)" "unprognostic (4.63e-2)" "unprognostic (1.84e-3)" "unprognostic (3.35e-1)" "unprognostic (9.58e-2)" "unprognostic (8.93e-3)" 12.2 13.0 7.1 10.1 7.2 18.0 16.4 8.6 8.3 12.9 6.9 20.2 20.8 9.7 13.8 16.3 11.6 9.0 11.0 6.9 8.5 17.2 14.1 9.2 7.5 7.2 7.7 8.6 9.4 8.2 9.4 12.6 7.8 15.1 22.1 10.3 12.1 10.0 11.9 8.7 16.3 10.5 6.8 5.5 13.0 10.7 7.6 10.7 13.4 18.7 10.3 12.9 10.3 7.8 47.5 28.4 52.4 23.1 21.2 30.3 37.8 37.7 35.8 41.3 39.7 42.1 45.2 34.6 20.7 30.3 36.7 54.3 51.3 56.1 63.4 18.3 41.8 34.1 28.0 46.2 19.8 52.0 31.2 20.9 35.3 33.3 46.7 18.4 45.3 34.5 30.7 13.5 67.2 23.2 40.5 48.4 83.0 72.8 32.2 27.6 33.8 22.7 46.2 35.8 31.4 33.1 25.6 43.8 30.3 44.7 22.5 38.7 23.0 28.5 34.7 36.2 53.3 6.9 12.5 43.6 14.8 40.1 47.4 1.6 4.8 3.5 2.9 6.9 2.9 3.1 4.6 3.6 4.9 2.6 5.3 5.8 1.0 2.8 4.8 3.7 3.4 2.7 7.1 7.2 8.6 8.3 6.9 8.5 7.2 7.7 7.8 6.8 7.6 7.8 12.0 12.8 15.7 0.7 14.7 16.6 34.6 18.1 19.9 9.2 14.0 11.6 12.5 12.8 20.7 7.3 2.1 36.2 12.6 30.4 49.0 17.3 16.7 45.7 20.4 15.1 8.4 10.5 3.9 17.6 79.4 12.8 18.3 39.5 9.5 8.7 7.5 17.4 16.8 38.7 3.1 23.5 26.4 7.8 10.5 9.3 16.8 11.4 10.6 1.9 10.3 10.8 6.2 0.5 3.0 16.4 18.3 12.4 16.8 41.9 18.9 40.8 13.6 9.0 0.0 9.5 17.1 8.9 34.4 34.9 20.5 38.0 13.2 15.3 31.9 42.0 NUDT6 "FGF-AS, FGF2AS, gfg, gfg-1" ENSG00000170917 "Nudix hydrolase 6" P53370 4 122888697-122922968 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 27.3" "Cell type enhanced" "Detected in many" "Distal tubular cells: 37.2;Early spermatids: 36.7;Proximal tubular cells: 46.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039202, HPA066115" Uncertain NA NA "Cluster 37: B-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 32: U-937 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA039202: AB_10795032, HPA066115: AB_2685620" "unprognostic (7.51e-2)" "unprognostic (1.59e-1)" "unprognostic (1.46e-3)" "unprognostic (1.97e-2)" "unprognostic (3.11e-1)" "unprognostic (3.84e-2)" "unprognostic (4.23e-2)" "unprognostic (2.36e-1)" "unprognostic (3.79e-1)" "unprognostic (1.07e-1)" "unprognostic (6.29e-2)" "unprognostic (6.91e-6)" "unprognostic (1.13e-5)" "unprognostic (2.32e-1)" "unprognostic (7.60e-2)" "unprognostic (7.98e-2)" "unprognostic (2.16e-1)" 4.9 10.7 8.2 2.8 9.4 2.2 5.3 5.8 10.6 4.2 6.6 7.7 4.4 4.1 7.1 3.3 6.7 3.6 13.0 8.4 8.2 19.4 27.3 3.2 3.9 6.0 7.3 4.2 4.0 7.4 6.4 3.2 6.1 3.7 6.2 8.3 5.2 4.3 10.0 4.2 3.7 3.5 5.9 4.5 3.3 7.1 9.0 4.8 7.3 10.9 2.3 3.2 3.2 7.8 5.4 7.9 11.5 10.3 10.3 10.7 4.1 6.1 8.1 5.3 7.3 3.4 12.1 5.6 4.5 3.3 11.7 2.7 5.1 4.8 5.4 13.5 3.4 5.0 7.6 9.2 3.8 10.4 3.0 6.6 2.1 4.6 4.0 9.8 7.0 9.7 12.8 13.8 9.0 6.3 14.5 11.2 4.3 20.8 9.9 4.9 14.6 6.4 12.7 3.2 6.1 7.6 6.3 8.5 12.5 13.3 5.6 8.3 4.4 12.8 6.7 11.2 5.6 15.4 12.9 10.7 7.7 15.4 5.8 0.0 2.0 0.0 1.5 2.8 1.9 4.0 2.0 2.6 4.4 1.2 1.5 1.7 0.3 1.3 2.5 1.7 2.3 1.8 8.2 9.4 5.8 10.6 8.4 8.2 6.0 7.3 6.1 5.9 9.0 7.8 7.0 16.0 7.8 10.7 2.0 0.9 3.1 9.3 4.6 12.5 4.7 6.9 5.3 4.3 5.4 5.5 0.0 16.4 1.3 4.1 37.2 6.2 36.7 8.9 7.4 5.4 7.2 3.0 8.9 5.6 3.7 5.3 5.6 3.4 1.3 12.8 4.6 21.3 8.7 15.2 9.6 6.0 6.1 4.6 2.0 6.1 6.2 5.0 5.4 4.7 1.5 14.0 0.0 13.6 10.8 4.7 5.2 9.1 3.8 1.2 2.5 46.2 10.4 11.9 0.0 6.3 5.0 28.5 3.7 3.9 1.8 4.0 3.3 20.8 10.1 2.1 NUP50 NPAP60L ENSG00000093000 "Nucleoporin 50" Q9UKX7 22 45163925-45188017 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047162, HPA048328" Enhanced Enhanced "Nucleoplasm,Nuclear membrane" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Nuclear membrane" "HPA047162: AB_2679963, HPA048328: AB_2680360" "unprognostic (2.64e-1)" "unprognostic (1.21e-2)" "unprognostic (4.96e-2)" "unprognostic (1.22e-1)" "unprognostic (2.17e-1)" "unprognostic (1.57e-1)" "unprognostic (5.46e-3)" "unprognostic (5.83e-3)" "unprognostic (4.94e-2)" "unprognostic (4.94e-2)" "unprognostic (7.22e-2)" "unprognostic (5.31e-2)" "unprognostic (1.97e-2)" "prognostic favorable (4.06e-4)" "unprognostic (1.43e-1)" "unprognostic (3.17e-2)" "unprognostic (3.63e-2)" 14.1 14.8 8.6 23.3 9.9 54.4 13.5 11.9 12.1 14.3 11.2 18.7 16.6 10.1 18.7 20.5 18.1 14.3 7.2 10.7 10.2 13.7 23.5 14.6 33.7 8.1 8.3 13.9 15.9 15.8 6.7 15.5 7.8 12.2 16.7 10.9 11.7 13.4 7.8 19.0 16.3 11.4 8.0 25.5 24.2 29.8 9.2 46.6 15.2 12.7 35.3 19.3 12.3 9.7 75.8 35.5 67.1 43.7 31.0 31.8 70.9 61.9 41.1 46.9 47.1 77.6 32.9 82.7 28.1 41.0 35.1 52.0 83.4 50.5 67.3 44.3 87.4 72.6 54.8 47.7 32.2 193.7 73.7 38.8 34.1 60.1 45.2 22.7 52.4 71.4 76.5 84.3 49.0 50.8 88.2 50.5 50.4 50.0 36.3 91.8 40.7 58.0 37.0 72.5 41.7 40.4 61.5 37.9 74.0 50.9 23.6 50.3 48.3 99.1 88.6 51.6 52.7 58.4 51.3 119.0 37.1 49.2 70.4 55.1 39.1 80.5 20.3 40.2 27.8 19.5 24.5 23.5 25.5 18.1 28.4 19.6 92.7 30.6 24.2 13.9 25.8 34.2 8.6 9.9 11.9 12.1 10.7 10.2 8.1 8.3 7.8 8.0 9.2 9.7 42.7 9.6 27.9 6.2 32.7 85.5 51.9 26.4 48.3 14.6 26.2 16.3 10.8 22.8 29.6 33.1 12.5 22.6 47.5 34.2 13.7 18.9 46.3 56.3 34.7 29.7 17.4 72.4 16.4 20.9 39.8 21.8 59.1 47.3 34.7 23.9 33.2 38.5 28.1 13.5 15.3 24.4 20.3 47.5 32.8 83.3 14.6 33.4 24.9 11.2 56.9 11.1 42.2 11.6 12.5 29.8 33.5 13.9 49.0 60.8 16.9 22.8 50.0 16.3 26.3 15.9 17.1 45.9 44.3 60.6 89.4 56.6 47.1 23.5 26.3 95.3 NUP88 MGC8530 ENSG00000108559 "Nucleoporin 88" Q99567 17 5360963-5419676 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 146.0;Spermatocytes: 147.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002209, HPA021816" Approved Approved Nucleoplasm NA NA "Cluster 37: B-cells - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "CAB002209: AB_564128, HPA021816: AB_1854725" "unprognostic (3.46e-2)" "unprognostic (1.66e-2)" "unprognostic (1.04e-2)" "unprognostic (8.83e-2)" "unprognostic (1.05e-1)" "unprognostic (2.03e-1)" "unprognostic (3.38e-2)" "unprognostic (3.94e-1)" "unprognostic (4.72e-2)" "unprognostic (4.94e-2)" "unprognostic (2.04e-2)" "unprognostic (5.75e-3)" "unprognostic (1.49e-1)" "unprognostic (1.10e-1)" "unprognostic (9.03e-2)" "unprognostic (1.14e-2)" "unprognostic (1.44e-2)" 11.8 12.0 4.2 16.3 3.8 20.8 15.2 7.5 6.0 10.8 3.3 13.2 9.9 10.4 16.4 12.1 12.4 8.0 12.2 3.9 3.9 15.2 27.3 9.4 26.4 4.1 4.0 8.5 10.2 15.3 9.0 10.9 4.3 11.5 19.3 9.6 13.2 10.3 31.2 12.9 11.7 13.7 3.6 14.8 12.3 49.3 3.8 24.1 14.6 21.6 32.9 15.1 9.0 4.2 46.2 50.0 44.0 33.3 18.3 20.0 40.2 35.8 29.0 58.7 52.0 41.5 17.8 88.6 13.3 33.1 38.1 43.5 73.6 39.6 74.7 22.7 48.6 40.0 42.7 32.5 24.8 31.8 34.6 14.3 28.2 43.7 71.3 24.5 41.0 34.3 42.3 22.2 46.5 24.3 46.7 23.4 41.2 46.4 23.9 44.1 48.5 38.7 30.7 22.3 17.5 33.9 44.0 20.4 28.1 33.7 22.9 37.3 26.8 26.4 28.3 27.1 66.9 15.0 19.4 39.5 31.3 36.3 37.4 5.4 7.6 4.3 12.4 12.2 12.3 39.1 13.3 15.0 10.9 35.7 14.3 15.9 0.9 21.1 14.3 12.2 17.6 11.5 4.2 3.8 7.5 6.0 3.9 3.9 4.1 4.0 4.3 3.6 3.8 4.2 6.9 12.8 17.8 10.1 38.0 22.2 31.5 13.5 14.2 13.3 8.9 6.2 10.7 11.5 18.1 16.5 16.7 30.1 19.3 15.2 11.7 27.9 146.0 26.1 15.0 11.5 13.8 28.6 22.9 25.4 24.8 12.2 15.3 47.2 7.6 14.9 9.3 16.5 11.4 10.1 20.4 10.1 14.2 7.9 12.3 38.0 15.2 10.6 3.6 11.2 19.4 7.8 26.8 13.0 17.8 23.3 15.4 10.9 9.4 21.7 9.9 7.5 11.5 11.0 13.1 19.5 20.5 147.5 61.8 15.8 17.0 36.0 17.9 13.6 17.6 42.8 NUSAP1 "ANKT, BM037, FLJ13421, LNP, PRO0310p1, Q0310, SAPL" ENSG00000137804 "Nucleolar and spindle associated protein 1" Q9BXS6 15 41320794-41381050 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 88.6;lymphoid tissue: 101.5" "Cell type enhanced" "Detected in many" "Erythroid cells: 266.7;Extravillous trophoblasts: 121.2;Granulosa cells: 93.3;Spermatocytes: 99.6" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 15 "basophil: 10.7;T-reg: 7.7" "Group enriched" "Detected in many" 15 "granulocytes: 10.7;T-cells: 7.7" "Low cell line specificity" "Detected in many" "HPA042904, HPA074847" Supported Approved "Nucleoplasm,Nucleoli,Nucleoli fibrillar center" Yes Yes "Cluster 34: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nucleoli, Nucleoli fibrillar center" "HPA042904: AB_2678220, HPA074847: AB_2732269" "unprognostic (1.19e-1)" "unprognostic (9.53e-3)" "unprognostic (1.65e-1)" "unprognostic (8.78e-2)" "unprognostic (3.46e-2)" "unprognostic (2.97e-2)" "unprognostic (1.16e-3)" "unprognostic (1.74e-3)" "unprognostic (1.37e-2)" "unprognostic (4.14e-1)" "prognostic unfavorable (6.27e-4)" "unprognostic (8.49e-3)" "prognostic unfavorable (6.82e-14)" "unprognostic (4.76e-3)" "unprognostic (1.23e-1)" "unprognostic (2.18e-1)" "unprognostic (1.22e-1)" 1.8 14.1 0.2 7.8 0.2 88.6 1.5 0.3 0.4 3.6 0.3 6.1 7.0 1.1 0.1 17.7 1.1 1.0 1.1 0.2 0.2 2.6 5.0 3.8 28.7 0.3 0.4 4.4 1.3 0.0 0.6 6.5 0.3 1.1 8.0 0.1 3.6 0.6 5.4 9.4 7.4 2.7 0.2 7.8 4.5 10.9 0.3 101.5 0.9 0.1 31.5 1.9 6.4 0.3 146.0 38.3 165.1 64.6 3.5 5.9 37.0 107.4 74.6 138.9 130.6 58.4 67.0 63.5 42.5 44.4 99.1 107.6 104.2 46.2 132.4 98.5 62.3 149.6 102.0 50.7 0.2 67.3 57.2 0.9 1.3 69.1 37.3 21.7 72.0 104.2 70.1 237.5 105.7 30.7 147.5 82.2 59.8 139.8 55.0 136.5 156.5 67.5 42.4 29.3 85.7 55.2 129.8 88.5 25.7 46.0 106.2 76.1 33.7 89.9 104.8 101.5 206.2 81.3 145.8 200.5 42.1 163.6 171.2 10.7 0.1 0.5 0.1 0.0 0.0 0.3 0.5 0.5 0.3 0.6 0.0 0.3 0.2 0.4 0.0 0.3 7.7 0.5 0.2 0.2 0.3 0.4 0.2 0.2 0.3 0.4 0.3 0.2 0.3 0.3 1.9 0.0 1.5 1.3 14.2 38.5 10.3 21.2 31.9 0.9 9.9 13.7 1.1 17.2 5.0 0.0 0.0 72.2 13.4 14.4 3.9 2.3 33.2 10.7 11.6 7.3 3.0 266.7 1.4 0.5 121.2 14.6 25.5 21.8 7.0 93.3 10.8 3.9 36.7 0.0 1.5 15.5 24.4 13.8 22.7 14.6 0.3 17.5 3.6 1.9 6.1 1.9 4.1 1.0 1.3 1.5 0.4 1.9 57.2 5.3 2.6 5.4 1.1 1.0 0.0 2.8 12.1 99.6 59.9 69.5 24.9 19.3 22.9 38.8 30.0 10.3 NUTF2 "NTF2, PP15" ENSG00000102898 "Nuclear transport factor 2" P61970 16 67846923-67872567 "Plasma proteins, Predicted intracellular proteins" "mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 336.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040915, HPA040956" Supported NA NA 2300000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "HPA040915: AB_10794073, HPA040956: AB_10796233" "unprognostic (1.74e-1)" "unprognostic (1.43e-1)" "unprognostic (1.59e-1)" "unprognostic (4.41e-3)" "unprognostic (1.17e-1)" "prognostic unfavorable (1.15e-4)" "unprognostic (1.08e-3)" "unprognostic (1.56e-3)" "unprognostic (2.25e-1)" "unprognostic (2.33e-2)" "unprognostic (5.17e-3)" "unprognostic (9.80e-2)" "prognostic unfavorable (2.58e-4)" "unprognostic (1.79e-1)" "unprognostic (1.60e-1)" "unprognostic (9.73e-2)" "unprognostic (1.45e-1)" 57.1 53.7 86.4 36.5 86.6 42.0 49.8 88.8 93.4 47.4 75.3 57.9 27.4 60.7 49.4 53.7 47.9 26.6 74.7 88.4 96.6 50.8 51.5 49.9 47.8 96.2 99.6 42.4 56.9 41.6 43.0 49.8 99.2 44.6 42.6 17.2 40.5 32.5 93.4 58.7 42.8 58.0 90.7 41.4 45.9 56.6 88.3 57.4 39.3 79.2 53.3 57.9 45.2 91.7 149.0 174.8 186.9 212.2 92.8 94.1 249.9 118.8 102.8 165.4 134.1 222.3 152.5 169.2 107.7 161.3 95.9 130.3 235.4 176.2 179.3 65.9 225.5 114.2 73.6 357.5 124.0 161.6 83.1 123.4 114.1 152.9 190.7 91.0 175.5 127.7 164.2 59.1 173.6 301.8 257.3 311.1 318.9 152.4 117.6 228.2 121.5 254.2 218.9 128.5 169.6 164.4 266.4 109.5 93.6 174.5 161.0 137.3 147.4 140.3 168.3 104.2 144.0 94.8 131.0 367.5 92.9 113.0 147.8 47.8 64.0 27.4 61.0 95.7 70.1 52.7 64.9 60.3 81.5 51.8 48.8 55.9 17.9 71.9 88.3 78.7 72.8 101.8 86.4 86.6 88.8 93.4 88.4 96.6 96.2 99.6 99.2 90.7 88.3 91.7 67.6 57.7 20.2 4.9 58.6 68.2 79.5 136.5 64.9 15.9 62.8 53.7 38.7 27.1 58.5 49.7 2.1 208.2 62.4 66.2 137.0 196.5 9.9 71.4 66.1 71.9 98.3 126.4 6.9 105.1 336.1 57.6 60.6 52.7 39.3 65.1 28.2 22.5 149.4 20.2 7.4 69.1 89.5 32.4 83.6 20.8 33.2 75.2 58.7 4.7 130.2 26.5 69.0 4.0 8.3 198.8 93.3 42.9 86.2 166.0 96.5 124.1 53.7 7.6 13.1 48.5 187.5 54.6 82.0 88.7 87.7 183.5 62.9 62.1 95.6 114.5 NYNRIN "CGIN1, FLJ11811, KIAA1305" ENSG00000205978 "NYN domain and retroviral integrase containing" Q9P2P1 14 24399003-24419283 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 18.2;Squamous epithelial cells: 18.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 14.4;HEL: 14.7;HUVEC TERT2: 35.6;RT4: 29.8;TIME: 17.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018945 Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus" "Nucleoplasm, Vesicles" "HPA018945: AB_1859538" "unprognostic (9.41e-3)" "unprognostic (3.96e-2)" "unprognostic (2.02e-1)" "unprognostic (4.49e-3)" "unprognostic (5.08e-2)" "unprognostic (1.14e-2)" "unprognostic (2.56e-1)" "unprognostic (2.65e-2)" "unprognostic (1.44e-3)" "unprognostic (4.21e-1)" "unprognostic (1.01e-1)" "unprognostic (4.51e-2)" "unprognostic (3.59e-2)" "unprognostic (2.39e-2)" "unprognostic (1.86e-1)" "unprognostic (3.39e-1)" "unprognostic (2.43e-1)" 8.7 3.7 4.3 3.1 3.9 0.4 6.3 16.3 4.6 16.8 5.4 7.6 4.0 11.5 28.0 11.6 16.9 8.6 7.5 3.2 6.6 6.3 4.5 8.1 1.9 5.8 5.4 35.1 3.8 5.8 5.8 12.8 6.3 7.5 5.5 1.8 7.4 14.9 3.8 13.3 5.3 10.5 3.2 4.4 6.0 5.1 7.8 4.5 7.8 4.2 2.9 9.5 14.0 2.8 0.2 0.1 4.6 0.0 6.3 13.0 0.3 2.2 2.3 1.5 1.6 3.3 14.4 0.4 0.6 8.6 0.2 0.0 7.5 0.2 1.5 0.0 0.8 14.7 2.0 0.3 4.7 0.0 0.0 13.3 0.6 1.0 0.0 2.6 35.6 0.1 2.4 0.0 0.2 0.6 0.0 0.8 2.7 1.0 0.0 1.9 0.0 0.0 0.0 29.8 0.6 10.0 0.0 1.3 0.2 11.2 2.5 2.1 17.4 0.1 8.2 0.0 0.0 0.0 0.4 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 4.3 3.9 16.3 4.6 3.2 6.6 5.8 5.4 6.3 3.2 7.8 2.8 15.2 3.2 1.7 4.9 0.1 4.6 3.9 9.5 15.4 0.5 1.8 3.6 3.1 8.6 15.6 9.2 0.0 1.1 1.6 2.7 0.0 4.1 0.8 1.4 10.8 15.0 5.4 3.6 1.0 3.0 1.0 10.1 10.7 1.7 0.0 12.0 18.2 2.7 10.7 0.0 3.9 9.0 4.1 9.0 1.4 0.2 2.5 1.4 3.6 3.7 0.7 5.4 0.0 0.5 0.1 4.8 5.1 0.4 1.2 1.2 1.0 0.3 10.8 0.2 0.0 1.2 7.3 0.3 1.2 18.0 3.8 1.1 0.3 1.5 8.8 4.5 OBI1 "C13orf7, FLJ13449, RNF219" ENSG00000152193 "ORC ubiquitin ligase 1" Q5W0B1 13 78614289-78659155 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 14.5;Cardiomyocytes: 19.5;Cytotrophoblasts: 15.8;dendritic cells: 8.0;Extravillous trophoblasts: 12.2;Hofbauer cells: 9.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034785, HPA034786" Enhanced Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 32: U-937 - Innate immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Nuclear bodies" Cytosol "HPA034785: AB_10601496, HPA034786: AB_2674331" "unprognostic (2.99e-1)" "unprognostic (1.11e-1)" "unprognostic (1.79e-1)" "unprognostic (2.60e-1)" "unprognostic (7.88e-2)" "unprognostic (1.34e-2)" "unprognostic (2.83e-3)" "unprognostic (1.50e-1)" "unprognostic (1.67e-2)" "unprognostic (1.45e-1)" "unprognostic (3.84e-2)" "unprognostic (4.26e-3)" "prognostic unfavorable (4.99e-6)" "unprognostic (6.87e-2)" "unprognostic (2.01e-1)" "unprognostic (6.91e-2)" "unprognostic (2.53e-2)" 5.8 4.8 5.4 6.1 5.8 2.4 6.7 6.6 6.7 5.9 3.0 4.8 4.8 7.1 4.5 5.0 5.6 4.5 7.1 5.6 6.1 4.6 4.4 5.2 9.9 5.5 5.9 7.6 4.1 4.1 2.9 7.4 5.0 5.5 5.3 9.6 4.2 6.1 4.8 5.5 4.7 6.5 6.1 7.3 4.5 14.8 7.2 13.3 5.9 6.4 11.3 6.0 4.5 5.9 23.7 9.1 39.1 23.1 13.5 12.9 17.8 19.3 14.5 18.7 23.3 18.3 17.3 39.8 9.2 12.4 12.2 23.0 31.2 15.3 32.6 24.9 22.8 61.0 11.4 16.1 11.3 59.6 18.2 12.4 16.7 15.7 16.8 10.6 15.6 19.9 16.1 5.3 24.6 6.6 36.5 20.2 0.0 25.1 10.0 42.0 32.2 15.4 12.7 12.5 28.4 15.9 13.4 16.9 14.8 22.2 8.6 47.3 12.9 16.2 14.7 10.7 16.3 5.5 6.6 37.9 25.9 35.6 17.8 4.9 5.4 7.5 7.9 8.8 9.5 8.8 8.8 9.8 6.3 8.9 10.8 9.8 1.8 11.1 10.3 5.3 9.6 6.6 5.4 5.8 6.6 6.7 5.6 6.1 5.5 5.9 5.0 6.1 7.2 5.9 14.5 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.5 0.0 0.0 0.0 0.0 15.8 8.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 12.2 4.9 0.0 0.0 0.0 0.0 0.0 0.0 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 5.1 1.1 0.0 0.0 0.0 ODF1 "CT133, HSPB10, ODF27, ODFPG, RT7" ENSG00000155087 "Outer dense fiber of sperm tails 1" Q14990 8 102551589-102561018 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 590 "testis: 397.0" "Group enriched" "Detected in some" 19 "Early spermatids: 208.2;Late spermatids: 322.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA064295 Approved NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 25: Spermatids - Spermatogenesis" "HPA064295: AB_2685235" "unprognostic (3.79e-3)" 0.0 0.0 0.4 0.0 0.5 0.0 0.3 0.3 0.6 0.0 0.4 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.4 0.4 0.0 0.1 0.0 0.0 0.4 0.4 0.0 0.1 0.0 0.1 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.4 0.0 0.0 397.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.3 0.6 0.4 0.4 0.4 0.4 0.4 0.4 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 208.2 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 322.0 4.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 1.0 0.0 6.6 0.0 0.0 13.4 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OIP5 "CT86, hMIS18beta, MIS18B" ENSG00000104147 "Opa interacting protein 5" O43482 15 41309273-41332591 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 10.3;skeletal muscle: 10.3;testis: 20.9" "Cell type enhanced" "Detected in many" "Erythroid cells: 45.9;Extravillous trophoblasts: 24.0;Spermatocytes: 110.6;Spermatogonia: 56.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA052271, HPA059602" Enhanced Supported "Nuclear speckles,Vesicles" NA Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear speckles" Vesicles "HPA052271: AB_2681780, HPA059602: AB_2684079" "unprognostic (5.17e-2)" "unprognostic (7.26e-2)" "unprognostic (3.07e-1)" "unprognostic (1.59e-2)" "unprognostic (6.94e-2)" "unprognostic (6.58e-2)" "prognostic unfavorable (1.79e-4)" "prognostic unfavorable (2.26e-4)" "unprognostic (2.71e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (9.34e-5)" "unprognostic (5.51e-2)" "unprognostic (0.00e+0)" "unprognostic (3.84e-2)" "unprognostic (2.02e-1)" "unprognostic (5.75e-2)" "unprognostic (2.86e-2)" 0.6 1.7 0.1 3.3 0.2 10.3 1.2 1.2 0.4 0.9 0.2 4.1 3.5 0.8 0.3 3.8 0.4 0.6 1.5 0.2 0.2 0.3 1.2 0.5 5.8 0.2 0.4 1.5 0.3 0.1 0.1 2.3 0.4 0.5 3.9 0.7 0.8 0.6 10.3 3.3 3.9 1.1 0.1 1.7 1.5 20.9 0.2 9.1 0.4 0.8 5.2 0.7 1.3 0.5 33.7 17.8 34.3 24.9 1.7 2.1 32.4 20.0 9.3 24.5 26.1 31.8 16.2 19.8 17.0 7.7 37.8 51.0 35.7 16.1 19.2 42.4 40.1 42.4 49.8 33.6 0.4 46.5 22.1 0.7 3.2 13.8 14.5 5.2 21.1 40.8 59.4 37.3 16.5 16.3 27.1 34.8 30.9 50.4 37.9 32.9 28.4 30.5 11.1 15.4 53.7 17.5 33.7 34.3 9.6 13.7 33.7 26.3 10.0 24.5 37.3 24.6 36.6 17.0 83.2 71.1 7.1 56.5 35.9 0.0 0.4 0.5 0.2 0.7 0.8 1.0 0.7 0.8 0.7 1.2 1.3 0.8 0.0 1.2 0.4 4.1 3.1 0.8 0.1 0.2 1.2 0.4 0.2 0.2 0.2 0.4 0.4 0.1 0.2 0.5 0.2 0.0 0.5 1.0 2.7 4.1 0.9 3.6 1.2 0.0 1.1 2.2 0.2 0.0 1.8 0.0 0.0 15.0 1.7 2.3 0.0 0.4 12.0 1.9 0.6 0.9 0.0 45.9 2.2 0.4 24.0 1.7 5.1 1.1 1.3 5.2 0.0 0.8 7.5 0.0 2.1 3.0 8.2 2.2 1.8 10.8 0.9 1.2 0.0 0.0 0.6 1.1 2.1 1.5 2.5 0.2 0.5 1.2 10.9 0.4 0.9 0.3 0.0 0.3 6.6 1.0 1.1 110.6 56.8 8.3 2.4 3.8 1.2 2.1 7.6 0.9 OLFM2 "NOE2, OlfC" ENSG00000105088 "Olfactomedin 2" O95897 19 9853718-9936552 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 202.6;skin 1: 94.8" "Cell type enhanced" "Detected in many" "Astrocytes: 108.4;Basal keratinocytes: 125.0;Muller glia cells: 91.1;Oligodendrocyte precursor cells: 124.7;Suprabasal keratinocytes: 118.1" "Cancer enhanced" "Detected in all" "glioma: 96.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 49.7" "Group enriched" "Detected in many" 26 "granulocytes: 49.7;T-cells: 17.0" "Cell line enhanced" "Detected in many" "AN3-CA: 25.6;ASC diff: 23.4;BJ hTERT+: 18.5;SH-SY5Y: 24.3;U-2 OS: 28.7;WM-115: 25.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049961, HPA057771" Uncertain Approved Nucleoplasm "Secreted in other tissues" NA NA 2700000 "Cluster 52: Eosinophils - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 28: Keratinocytes - Keratinization" Nucleoplasm "HPA049961: AB_2680972, HPA057771: AB_2683524" "unprognostic (1.42e-2)" "unprognostic (3.93e-2)" "prognostic unfavorable (3.05e-4)" "unprognostic (1.99e-2)" "unprognostic (5.91e-2)" "unprognostic (3.39e-2)" "unprognostic (8.78e-2)" "unprognostic (4.47e-2)" "unprognostic (8.04e-2)" "unprognostic (4.03e-2)" "unprognostic (1.41e-3)" "unprognostic (2.77e-2)" "prognostic unfavorable (2.21e-4)" "unprognostic (6.23e-2)" "unprognostic (5.67e-2)" "unprognostic (1.41e-2)" "unprognostic (1.23e-1)" 36.8 30.7 130.8 3.4 134.5 0.2 25.0 118.5 202.6 17.2 80.7 4.8 2.1 16.7 4.5 5.6 11.1 6.7 10.1 134.0 127.3 9.2 41.9 10.1 7.9 152.5 168.8 9.7 11.2 9.6 19.1 7.1 162.0 10.1 1.1 24.6 10.0 13.4 1.8 94.8 3.8 6.7 130.0 2.5 2.2 10.7 123.2 16.5 13.2 1.0 4.8 3.0 14.1 120.7 0.0 3.7 3.0 25.6 23.4 14.3 1.7 5.6 18.5 1.2 1.5 0.3 2.4 0.1 2.3 4.2 2.1 1.5 9.8 1.7 0.1 0.1 2.1 0.0 0.2 0.3 0.1 0.0 4.3 7.5 1.5 0.1 0.2 0.7 0.1 4.8 0.3 0.3 0.0 8.2 0.3 0.2 15.8 2.5 0.0 0.1 0.0 0.0 0.0 0.9 0.1 24.3 0.9 0.1 5.2 9.7 0.9 0.0 0.3 10.5 28.7 0.1 0.1 0.0 0.0 0.0 0.3 0.0 25.6 21.2 0.0 49.7 6.2 0.0 6.6 0.0 7.0 5.5 0.0 0.0 13.5 8.9 0.5 1.2 0.0 0.1 17.0 2.9 130.8 134.5 118.5 202.6 134.0 127.3 152.5 168.8 162.0 130.0 123.2 120.7 12.9 0.0 0.0 108.4 0.3 125.0 4.7 5.9 8.6 4.9 6.9 13.8 0.8 7.2 0.4 7.3 0.0 0.1 1.0 0.1 1.9 0.9 8.6 0.9 2.2 4.3 1.2 0.4 27.3 2.4 0.0 17.2 0.0 1.0 4.5 6.5 1.4 24.7 0.3 1.7 51.0 0.2 2.0 0.3 32.6 52.8 13.7 0.6 17.8 15.0 0.4 91.1 7.2 124.7 3.5 4.1 0.0 9.8 0.5 7.9 0.0 0.2 0.2 3.7 0.0 7.4 24.3 3.0 10.4 1.4 118.1 0.1 7.7 0.6 0.1 2.9 OOSP2 "FLJ36198, OOSP2A, PLAC1L, TMEM122" ENSG00000149507 "Oocyte secreted protein 2" Q86WS3 11 60040409-60048044 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 180 "testis: 18.0" "Cell type enriched" "Detected in some" 5 "Late spermatids: 7.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA050914 Enhanced "Secreted in male reproductive system" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 74: Testis - Spermatogenesis" "Cluster 31: Spermatids - Spermatogenesis" "HPA050914: AB_2681271" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 7.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OPLAH "5-Opase, OPLA" ENSG00000178814 "5-oxoprolinase, ATP-hydrolysing" O14841 8 144051266-144063965 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 66.5" "Group enriched" "Detected in many" 4 "Early spermatids: 115.7;Late spermatids: 231.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.1;neutrophil: 1.1" "Group enriched" "Detected in many" 9 "granulocytes: 1.1;monocytes: 1.1" "Cell line enhanced" "Detected in many" "AN3-CA: 33.9;BEWO: 21.0;Hep G2: 18.8;PC-3: 26.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026562, HPA028260, HPA052429" Uncertain Approved "Nucleoli fibrillar center" NA NA 34000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoli fibrillar center" "HPA026562: AB_1854804, HPA028260: AB_10601383, HPA052429: AB_2681830" "unprognostic (7.89e-2)" "unprognostic (3.08e-2)" "unprognostic (1.69e-1)" "unprognostic (9.09e-2)" "unprognostic (2.21e-2)" "unprognostic (3.87e-3)" "unprognostic (2.04e-2)" "unprognostic (9.37e-2)" "unprognostic (2.90e-1)" "unprognostic (1.26e-1)" "unprognostic (6.82e-2)" "unprognostic (3.62e-1)" "prognostic favorable (1.53e-6)" "unprognostic (4.03e-3)" "unprognostic (4.33e-1)" "unprognostic (3.54e-2)" "unprognostic (8.24e-2)" 9.2 14.8 3.3 1.9 5.6 2.7 8.6 8.1 3.7 6.4 5.7 15.0 13.8 4.8 0.6 15.6 4.2 2.5 35.1 2.9 2.7 15.8 34.3 6.4 0.8 12.2 5.6 5.7 10.0 6.7 3.2 1.3 12.5 8.9 2.2 0.3 11.2 5.7 34.2 13.3 12.2 1.1 3.9 9.1 19.7 66.5 5.3 0.3 5.9 15.4 0.5 4.8 9.5 6.5 4.2 4.2 0.4 33.9 1.5 3.1 21.0 2.1 1.3 1.2 0.7 8.1 7.8 0.0 6.8 3.8 0.0 5.5 1.0 3.1 0.1 1.1 0.0 1.4 7.0 18.8 10.5 0.1 0.0 4.4 13.8 1.4 0.0 0.0 0.2 5.8 5.1 0.0 0.0 4.8 0.3 3.3 2.8 6.5 26.2 0.4 0.0 5.6 3.6 5.1 1.2 0.1 0.0 1.4 0.1 0.4 8.8 4.6 0.2 0.0 5.5 0.0 1.4 1.1 1.5 1.1 0.5 1.1 0.0 0.0 1.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.4 3.3 5.6 8.1 3.7 2.9 2.7 12.2 5.6 12.5 3.9 5.3 6.5 1.1 3.2 3.2 9.1 0.8 2.0 2.8 4.4 3.4 1.1 6.1 6.1 2.9 7.2 4.7 9.2 0.0 1.7 0.2 37.6 11.7 3.8 115.7 2.6 2.7 1.1 1.2 0.0 0.2 2.7 2.7 2.7 18.3 5.5 0.0 6.0 2.2 25.1 2.4 0.0 0.3 10.0 4.1 6.0 0.5 231.7 2.5 3.4 0.0 1.0 2.1 4.3 0.0 0.5 2.6 3.6 13.1 3.8 0.6 1.9 23.8 13.3 2.2 0.1 0.0 3.6 2.2 3.1 2.3 7.2 1.8 2.5 0.6 10.2 18.2 3.0 OPN5 "dJ402H5.1, neuropsin, TMEM13" ENSG00000124818 "Opsin 5" Q6U736 6 47781982-47832780 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Vision" "G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "testis: 2.6" "Group enriched" "Detected in some" 11 "Early spermatids: 27.1;Late spermatids: 25.6;Spermatocytes: 13.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA026084 Supported NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 25: Spermatids - Spermatogenesis" "HPA026084: AB_2671807" "unprognostic (1.95e-1)" "unprognostic (6.18e-2)" "unprognostic (4.84e-1)" "unprognostic (1.07e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.1 0.2 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 25.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.0 0.0 13.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OR1F1 "Olfmf, OR16-36, OR16-37, OR16-88, OR16-89, OR16-90, OR1F10, OR1F13P, OR1F4, OR1F5, OR1F6, OR1F7, OR1F8, OR1F9, OR3-145" ENSG00000168124 "Olfactory receptor family 1 subfamily F member 1" O43749 16 3204247-3205188 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 4 "brain: 2.9" "Cell type enhanced" "Detected in some" "Early spermatids: 4.0;Excitatory neurons: 1.4;Inhibitory neurons: 1.2;Late spermatids: 5.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "THP-1: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 6: Brain - Smell perception" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (3.72e-1)" "unprognostic (2.99e-2)" "unprognostic (1.22e-1)" "unprognostic (4.94e-2)" "unprognostic (4.88e-1)" "unprognostic (4.16e-1)" "unprognostic (1.26e-1)" 0.0 0.0 0.4 0.0 1.0 0.0 0.0 2.9 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.4 0.0 0.0 0.0 0.0 1.2 0.5 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.2 0.6 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.5 0.1 0.2 0.0 0.3 0.3 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.4 0.2 0.2 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.3 0.2 0.6 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.0 1.0 0.6 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 1.0 2.9 1.9 1.8 0.4 1.2 0.5 1.1 0.1 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OR2H2 hs6M1-12 ENSG00000204657 "Olfactory receptor family 2 subfamily H member 2" O95918 6 29585121-29590500 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 1.8;epididymis: 4.8;testis: 2.2" "Cell type enriched" "Detected in some" 5 "Early spermatids: 15.2" "Not detected" "Not detected" "Region enhanced" "Detected in single" "basal ganglia: 1.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 29: Early spermatids - Spermatogenesis" "unprognostic (2.95e-1)" "unprognostic (3.76e-1)" "unprognostic (2.33e-2)" "unprognostic (2.42e-1)" "unprognostic (2.34e-1)" "unprognostic (3.11e-1)" "unprognostic (2.76e-1)" "unprognostic (3.20e-1)" "unprognostic (1.34e-1)" "unprognostic (2.04e-1)" 0.1 0.0 0.5 0.1 1.8 0.7 0.0 0.8 0.6 0.3 0.0 0.1 0.0 0.1 4.8 0.1 0.2 0.0 0.3 0.5 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.3 0.0 0.0 0.5 0.0 0.0 0.3 0.0 1.5 0.0 0.3 0.0 0.1 0.1 0.0 0.0 0.1 0.1 2.2 0.2 0.0 0.1 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.8 0.8 0.6 0.5 0.0 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ORAI3 "MGC13024, TMEM142C" ENSG00000175938 "ORAI calcium release-activated calcium modulator 3" Q9BRQ5 16 30949068-30956461 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 77.3;Hofbauer cells: 93.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 94.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015022 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Cytosol" "HPA015022: AB_1854807" "unprognostic (1.17e-1)" "unprognostic (3.88e-2)" "unprognostic (2.94e-3)" "unprognostic (1.15e-2)" "unprognostic (8.29e-2)" "unprognostic (1.46e-1)" "unprognostic (8.60e-2)" "unprognostic (8.54e-2)" "unprognostic (3.15e-1)" "unprognostic (1.33e-3)" "unprognostic (1.77e-1)" "unprognostic (1.47e-1)" "prognostic unfavorable (3.87e-5)" "unprognostic (2.30e-2)" "unprognostic (4.46e-2)" "unprognostic (6.43e-3)" "unprognostic (9.17e-3)" 17.3 34.1 18.0 8.2 16.5 17.6 15.2 16.9 17.1 24.4 26.0 22.7 9.2 18.3 16.3 15.4 19.2 9.9 16.7 15.3 16.3 19.3 70.2 14.2 11.9 18.6 18.5 18.9 17.7 18.9 18.0 14.9 17.1 26.3 8.6 4.0 14.6 17.0 7.9 14.3 16.1 9.8 17.4 22.5 17.1 15.6 20.5 11.2 16.4 8.1 10.6 27.2 20.2 17.7 2.8 15.8 8.1 10.7 68.1 60.7 0.6 9.3 62.3 6.8 17.2 1.5 26.1 3.9 20.7 17.9 27.5 12.7 1.4 17.6 4.6 12.3 5.2 10.2 4.9 16.1 94.9 11.2 30.5 65.5 45.9 13.1 25.5 63.8 11.7 2.2 11.7 20.6 22.1 10.8 0.7 42.6 6.6 9.1 4.3 8.6 6.3 30.8 26.2 6.8 2.0 13.5 8.4 2.6 14.9 19.5 19.7 45.5 8.5 5.1 3.5 11.4 2.2 50.4 4.0 3.1 25.3 26.4 7.9 23.2 8.7 26.6 3.4 9.2 3.6 7.1 1.8 2.7 8.5 6.7 2.2 2.9 15.3 11.7 12.6 9.5 2.7 3.3 18.0 16.5 16.9 17.1 15.3 16.3 18.6 18.5 17.1 17.4 20.5 17.7 12.1 6.4 10.8 0.0 23.9 7.9 24.5 25.6 32.5 1.5 11.1 19.6 6.9 5.7 11.6 16.5 2.1 28.1 25.9 11.1 13.7 21.4 61.1 16.5 21.8 16.5 15.0 16.2 0.0 11.4 2.7 25.9 4.1 10.5 7.0 17.9 23.6 77.3 93.8 35.3 0.0 11.3 10.2 43.7 11.5 36.7 53.1 31.4 21.4 0.0 39.1 24.4 17.5 0.0 0.0 9.5 18.4 43.2 18.1 14.0 9.5 48.2 14.7 3.6 26.3 11.0 14.0 26.5 2.5 17.0 4.5 4.4 9.7 61.0 5.8 20.4 ORC6 ORC6L ENSG00000091651 "Origin recognition complex subunit 6" Q9Y5N6 16 46689643-46698394 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA replication" DNA-binding "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 10.3;lymphoid tissue: 7.4;testis: 9.6" "Cell type enhanced" "Detected in many" "Granulosa cells: 56.7;Spermatocytes: 102.6;Spermatogonia: 108.9;Theca cells: 47.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016330, HPA072587" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center" Yes No "Cluster 24: B-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nucleoli fibrillar center" "CAB016330: AB_670295, HPA072587: AB_2686537" "unprognostic (3.47e-2)" "unprognostic (8.99e-3)" "unprognostic (2.92e-1)" "unprognostic (4.47e-2)" "unprognostic (2.27e-1)" "unprognostic (2.19e-2)" "unprognostic (3.15e-6)" "unprognostic (1.36e-2)" "prognostic unfavorable (3.53e-4)" "prognostic favorable (1.48e-4)" "unprognostic (1.50e-4)" "unprognostic (3.97e-2)" "unprognostic (3.90e-14)" "unprognostic (2.08e-1)" "unprognostic (4.24e-1)" "unprognostic (2.79e-1)" "unprognostic (5.98e-2)" 0.3 0.7 2.0 2.2 1.6 10.3 0.6 1.5 1.9 0.7 1.0 1.7 1.5 0.8 1.1 4.1 0.4 0.6 1.5 1.9 1.8 0.4 0.9 0.6 7.4 1.5 1.9 0.4 0.3 0.7 0.6 3.3 1.7 0.3 1.9 0.3 0.7 0.2 0.1 1.1 1.5 1.0 1.6 2.4 0.8 9.6 1.8 6.2 0.5 0.3 7.3 1.2 1.3 1.8 28.6 27.4 43.7 33.9 5.4 6.8 31.6 54.2 20.2 59.3 30.9 39.3 18.0 35.6 27.1 10.5 29.1 29.9 57.9 15.1 50.4 17.2 46.4 27.9 13.2 40.1 6.6 46.5 23.7 1.8 2.6 32.4 17.1 9.3 20.0 30.1 36.0 17.4 35.9 26.9 65.6 60.7 48.1 20.7 76.0 78.6 80.6 35.8 14.9 9.8 52.2 30.4 24.5 29.8 18.1 34.9 15.6 37.9 11.6 53.7 34.6 33.6 51.8 12.5 18.9 123.2 22.2 29.5 40.1 0.0 0.3 0.3 0.9 0.7 0.4 0.7 0.5 0.5 0.6 1.4 0.8 0.3 0.0 0.8 0.8 1.0 1.2 0.7 2.0 1.6 1.5 1.9 1.9 1.8 1.5 1.9 1.7 1.6 1.8 1.8 1.6 3.2 14.5 1.0 8.8 6.6 2.2 3.6 8.6 6.6 4.1 5.8 3.7 1.5 6.3 5.5 4.2 39.3 6.0 9.5 1.9 2.5 13.2 6.5 7.5 4.3 1.8 45.4 6.3 0.7 40.9 8.0 7.1 9.4 1.3 56.7 0.7 9.9 15.7 11.8 2.7 12.4 6.1 3.8 11.9 8.9 2.8 7.7 33.8 2.8 1.2 2.5 2.1 0.0 2.0 2.1 1.4 3.4 18.5 2.6 2.3 1.0 10.7 10.2 0.0 5.1 7.3 102.6 108.9 16.9 6.0 10.9 7.5 47.5 14.4 2.7 ORMDL3 ENSG00000172057 "ORMDL sphingolipid biosynthesis regulator 3" Q8N138 17 39921041-39927601 "Disease related genes, Predicted membrane proteins" Asthma "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 234.5" "Cell type enhanced" "Detected in many" "Early spermatids: 251.6;Late spermatids: 328.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 427.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065643 Supported "Endoplasmic reticulum" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 34: Spermatids - Unknown function" "Endoplasmic reticulum" "HPA065643: AB_2685525" "unprognostic (2.28e-1)" "unprognostic (1.06e-1)" "unprognostic (3.31e-2)" "unprognostic (6.49e-2)" "unprognostic (4.11e-2)" "unprognostic (1.55e-1)" "unprognostic (2.96e-1)" "prognostic favorable (9.29e-4)" "unprognostic (1.26e-1)" "unprognostic (3.67e-1)" "unprognostic (5.68e-2)" "unprognostic (1.14e-1)" "unprognostic (1.31e-1)" "unprognostic (2.37e-1)" "unprognostic (4.55e-1)" "unprognostic (1.09e-3)" "prognostic favorable (5.18e-4)" 149.0 29.6 39.6 33.9 39.5 39.7 70.8 37.2 45.8 40.1 55.9 41.9 50.0 36.1 64.7 28.4 28.0 32.4 63.0 41.7 40.2 38.0 234.5 49.0 55.9 40.9 38.6 39.9 109.6 51.1 50.2 35.5 38.3 46.9 38.6 25.1 70.4 41.6 44.2 41.4 47.8 36.6 40.1 38.3 50.0 50.8 41.6 79.4 57.7 29.5 56.4 46.9 26.3 39.1 33.5 40.2 41.8 34.8 106.1 40.2 37.9 48.0 55.4 50.5 48.4 46.1 36.3 24.7 44.6 59.4 34.5 56.0 29.8 38.6 46.9 427.6 53.2 24.1 22.5 113.0 41.5 28.5 40.6 44.2 39.7 34.9 19.7 57.2 22.8 68.5 30.9 194.8 28.0 30.1 85.1 31.9 23.4 44.2 20.1 71.2 37.7 78.4 28.2 80.1 36.6 37.2 31.8 196.6 32.9 46.3 70.8 30.8 18.7 27.4 34.0 23.6 36.8 104.2 95.3 34.5 28.2 27.6 20.6 9.3 4.7 61.1 39.4 7.7 28.3 26.4 39.3 43.3 4.2 23.1 44.2 53.7 7.7 18.4 11.6 21.1 27.7 36.6 39.6 39.5 37.2 45.8 41.7 40.2 40.9 38.6 38.3 40.1 41.6 39.1 7.6 51.3 37.2 2.9 28.7 16.4 13.7 13.1 21.6 18.5 25.9 14.5 28.9 17.2 15.3 42.3 0.0 25.9 18.4 27.3 3.9 18.4 251.6 7.2 12.6 10.3 25.9 34.1 3.4 29.2 17.9 13.9 11.2 13.8 18.4 10.5 7.5 97.8 8.3 13.5 3.8 26.8 18.3 7.5 13.0 328.9 18.6 6.0 16.0 1.9 22.1 44.9 57.7 3.5 3.2 38.8 20.8 28.6 41.2 15.2 29.2 11.9 8.0 11.2 26.3 8.5 16.5 5.8 7.6 11.5 14.3 9.3 35.6 21.0 17.7 12.4 OTOP2 ENSG00000183034 "Otopetrin 2" Q7RTS6 17 74922950-74933912 "Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "intestine: 20.1" "Cell type enriched" "Detected in some" 20 "Paneth cells: 627.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 41 "HDLM-2: 10.1" "Region enriched" "Detected in some" 12 "olfactory bulb: 12.7" "Low region specificity" "Detected in many" "HPA024524, HPA053090" Uncertain Approved "Plasma membrane" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "HPA024524: AB_2671592, HPA053090: AB_2682041" "unprognostic (1.62e-2)" "unprognostic (1.45e-1)" "unprognostic (7.25e-2)" "unprognostic (3.21e-2)" "unprognostic (3.62e-1)" "unprognostic (1.30e-1)" "unprognostic (2.85e-2)" "unprognostic (3.81e-1)" "unprognostic (9.04e-2)" "unprognostic (2.04e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.1 0.3 0.2 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 0.0 0.0 0.1 0.0 0.2 1.4 0.3 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 30.0 0.0 0.0 9.3 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.0 0.0 19.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 627.4 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 4.1 0.0 OTUD7B "CEZANNE, ZA20D1" ENSG00000264522 "OTU deubiquitinase 7B" Q6GQQ9 1 149937812-150010726 "Enzymes, Predicted intracellular proteins" "Adaptive immunity, Immunity, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 43.0" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 106.3;Oligodendrocytes: 176.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.0" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027045, HPA076357" Supported Uncertain "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 41: Basophils - Cellular respiration" "Cluster 70: Brain - Nervous system development" "Cluster 2: Karpas-707 - Immune response" "Cluster 9: Photoreceptor cells - Phototransduction" Microtubules "Cytokinetic bridge, Mitotic spindle" "HPA027045: AB_1854847, HPA076357: " "unprognostic (2.17e-2)" "unprognostic (2.93e-2)" "unprognostic (1.90e-1)" "prognostic favorable (7.47e-4)" "unprognostic (1.51e-1)" "unprognostic (1.05e-1)" "unprognostic (1.23e-3)" "unprognostic (1.46e-2)" "prognostic favorable (5.09e-5)" "unprognostic (4.90e-2)" "unprognostic (7.72e-2)" "unprognostic (8.94e-2)" "unprognostic (3.37e-2)" "unprognostic (1.67e-2)" "unprognostic (1.18e-1)" "unprognostic (4.52e-2)" "unprognostic (1.58e-2)" 11.7 7.7 21.0 3.8 39.2 1.1 7.8 28.7 18.5 9.9 6.8 7.6 6.2 10.5 3.8 7.7 9.3 4.8 7.1 15.3 22.1 5.6 10.7 7.3 1.9 41.4 37.2 10.9 6.1 10.9 3.4 7.1 35.5 6.6 7.1 10.1 7.8 7.5 18.6 5.8 6.2 10.8 27.9 3.6 6.7 12.7 31.7 2.1 6.7 16.2 3.2 6.3 5.2 43.0 17.2 13.5 9.3 15.6 12.0 11.1 8.8 11.8 17.3 14.0 9.6 10.0 13.6 0.2 7.5 21.7 6.3 13.4 13.2 13.1 14.6 16.5 6.7 6.6 18.9 6.8 12.8 7.6 6.9 12.4 9.9 23.7 20.6 10.9 11.5 2.0 18.4 18.1 10.1 17.5 1.3 2.1 11.9 12.8 13.1 1.8 12.9 4.4 5.4 23.2 6.0 11.4 20.8 15.2 18.5 12.1 12.6 4.0 13.9 14.4 13.2 9.8 14.0 19.1 20.0 2.0 12.8 2.2 24.1 2.0 0.0 0.4 0.7 0.0 0.5 0.1 0.3 0.4 0.0 0.1 0.2 0.3 0.3 0.4 0.0 0.1 0.1 0.0 21.0 39.2 28.7 18.5 15.3 22.1 41.4 37.2 35.5 27.9 31.7 43.0 10.2 35.3 11.7 56.8 3.0 15.9 22.7 8.7 13.1 28.0 18.3 9.3 22.2 12.8 15.3 11.0 106.3 23.5 5.1 41.1 7.9 14.5 63.4 21.8 17.8 16.7 17.4 14.9 20.6 11.1 11.6 14.8 21.4 40.2 0.0 22.0 20.3 33.0 3.1 23.5 24.6 15.8 8.2 0.8 5.9 79.4 14.6 2.4 37.4 22.5 4.3 23.6 15.5 33.2 176.8 20.6 21.3 23.0 4.7 20.2 17.1 11.5 17.4 66.9 0.0 19.8 17.9 11.1 7.2 11.8 16.6 21.2 7.5 11.1 11.1 34.0 P2RY13 "FKSG77, GPR86, GPR94, P2Y13" ENSG00000181631 "Purinergic receptor P2Y13" Q9BPV8 3 151326312-151329549 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 25.1;lymphoid tissue: 36.9" "Group enriched" "Detected in some" 9 "Kupffer cells: 124.4;Macrophages: 53.2;Microglial cells: 66.5;monocytes: 63.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 581.5" "Group enriched" "Detected in many" 6 "granulocytes: 581.5;monocytes: 185.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049047 Enhanced NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA049047: AB_2680611" "unprognostic (1.09e-3)" "unprognostic (7.51e-4)" "unprognostic (1.68e-2)" "unprognostic (2.37e-3)" "unprognostic (3.95e-2)" "unprognostic (8.66e-3)" "unprognostic (7.66e-2)" "unprognostic (5.48e-3)" "unprognostic (2.84e-3)" "unprognostic (1.83e-1)" "unprognostic (4.97e-2)" "unprognostic (1.17e-1)" "unprognostic (4.05e-1)" "unprognostic (4.46e-1)" "unprognostic (5.95e-2)" "unprognostic (2.21e-3)" "unprognostic (3.78e-1)" 4.8 3.8 1.6 20.6 1.6 25.1 4.2 1.6 2.2 2.6 2.7 4.5 4.6 1.9 0.8 3.2 3.1 3.9 1.4 1.9 2.0 1.6 8.2 7.6 18.2 3.1 2.4 1.6 1.2 1.6 0.5 3.3 2.8 1.4 6.2 0.1 2.9 3.2 0.7 2.1 11.0 5.3 3.7 36.9 3.1 0.7 4.2 4.5 1.3 3.8 8.4 4.1 0.3 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 152.5 137.2 0.3 155.4 0.3 1.5 0.2 0.2 66.4 0.6 0.2 0.3 581.5 0.1 185.6 1.1 0.2 77.6 1.6 1.6 1.6 2.2 1.9 2.0 3.1 2.4 2.8 3.7 4.2 4.0 0.9 0.0 6.1 0.0 1.3 0.0 0.1 0.0 0.0 0.8 0.6 0.6 0.4 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.1 0.0 0.0 2.7 0.0 3.6 0.3 0.0 0.2 0.6 0.5 0.0 2.5 0.0 0.7 0.4 7.7 1.7 0.2 0.0 0.0 124.4 4.5 0.0 0.0 53.2 0.0 66.5 63.3 1.1 2.1 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.2 0.0 0.2 0.1 0.0 0.0 0.1 0.1 0.1 0.9 0.0 0.0 0.0 P2RY2 P2U ENSG00000175591 "Purinergic receptor P2Y2" P41231 11 73218281-73242427 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 29.7;skeletal muscle: 50.2;tongue: 31.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 16.5;Distal enterocytes: 18.0;Pancreatic endocrine cells: 18.9;Proximal enterocytes: 14.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 57.6" "Group enriched" "Detected in many" 12 "granulocytes: 57.6;monocytes: 20.2" "Cell line enhanced" "Detected in many" "HaCaT: 32.8;HL-60: 30.8;MCF7: 25.1;NB-4: 26.1;PC-3: 24.5;SK-BR-3: 29.6;THP-1: 76.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" CAB022642 Uncertain Uncertain Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 43: THP-1 - Innate immune response" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol "CAB022642: " "unprognostic (1.24e-1)" "unprognostic (1.13e-1)" "unprognostic (6.36e-2)" "unprognostic (7.97e-3)" "unprognostic (6.50e-4)" "unprognostic (2.04e-2)" "unprognostic (4.66e-3)" "unprognostic (8.93e-2)" "unprognostic (2.87e-1)" "unprognostic (4.17e-2)" "prognostic unfavorable (2.19e-5)" "unprognostic (9.69e-2)" "unprognostic (4.92e-4)" "unprognostic (1.34e-1)" "unprognostic (2.82e-1)" "unprognostic (1.05e-1)" "unprognostic (8.57e-3)" 0.8 3.8 1.4 1.8 1.6 15.8 1.7 1.3 1.0 6.9 1.1 3.3 2.7 0.5 0.3 29.7 1.4 0.7 10.0 1.3 1.8 2.7 3.9 3.5 0.1 2.1 1.9 0.4 0.7 4.8 1.6 2.0 1.6 2.1 2.8 1.2 6.2 1.2 50.2 6.0 5.9 0.5 1.3 3.9 1.1 1.2 2.6 0.2 8.8 31.3 2.8 2.2 19.0 1.4 7.2 6.7 0.0 0.0 0.0 0.0 2.4 0.1 0.0 0.0 0.0 17.2 5.4 0.0 10.4 0.4 0.0 32.8 0.9 15.2 0.0 0.0 0.6 2.3 0.6 3.2 0.1 30.8 0.0 0.0 6.8 2.3 0.5 0.0 1.4 0.0 1.4 0.0 0.0 25.1 0.1 26.1 0.4 6.8 24.5 0.0 0.0 1.1 2.4 17.9 0.0 0.0 0.5 29.6 0.0 0.2 12.9 76.5 10.2 0.0 0.3 0.0 0.0 1.0 0.4 0.0 0.0 5.6 0.0 0.5 6.6 57.6 0.0 20.2 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.3 0.0 13.5 0.0 0.0 2.5 1.4 1.6 1.3 1.0 1.3 1.8 2.1 1.9 1.6 1.3 2.6 1.4 0.7 3.2 0.5 0.0 0.2 3.7 8.6 13.2 1.2 0.7 2.8 0.5 6.1 5.7 10.3 0.0 0.0 16.5 0.0 18.0 1.9 5.8 6.0 1.4 0.1 1.5 0.0 0.8 0.0 6.3 1.3 0.7 0.5 0.8 0.0 1.2 0.0 5.2 2.6 0.0 0.0 5.1 0.0 3.7 0.7 8.8 0.0 4.5 0.0 0.0 2.8 6.0 0.0 0.0 0.1 18.9 10.9 0.0 0.2 5.3 14.2 0.3 2.8 0.4 0.0 0.8 1.4 0.1 0.1 12.6 7.2 10.9 0.1 0.1 3.0 11.7 PABPC1L "C20orf119, dJ1069P2.3, ePAB, PABPC1L1" ENSG00000101104 "Poly(A) binding protein cytoplasmic 1 like" Q4VXU2 20 44910060-44959035 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 24.6;Collecting duct cells: 20.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA066650 Approved "Nuclear bodies,Cytosol" NA Yes "Cluster 50: Neutrophils - Cellular senescence" "Cluster 18: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 52: Non-specific - Transcription" Cytosol "Nuclear bodies" "HPA066650: AB_2685698" "unprognostic (4.98e-2)" "unprognostic (2.78e-1)" "prognostic unfavorable (3.80e-4)" "unprognostic (1.73e-2)" "unprognostic (2.26e-1)" "unprognostic (2.24e-2)" "unprognostic (1.77e-3)" "unprognostic (4.92e-3)" "unprognostic (3.69e-2)" "unprognostic (2.44e-1)" "unprognostic (2.28e-3)" "unprognostic (7.96e-2)" "prognostic unfavorable (4.00e-15)" "unprognostic (1.01e-1)" "unprognostic (1.88e-1)" "unprognostic (8.63e-2)" "prognostic favorable (8.84e-4)" 2.1 2.3 1.7 2.0 1.8 4.1 2.9 1.1 2.1 4.0 2.5 1.7 0.8 1.5 3.4 2.1 3.4 1.4 1.3 1.7 1.8 6.1 5.9 2.9 3.3 1.4 1.8 6.6 6.1 0.5 6.1 0.6 1.4 5.2 0.6 0.4 2.5 0.9 0.5 2.1 2.9 0.6 1.3 4.4 2.8 1.9 2.5 3.0 7.9 0.1 1.9 1.9 1.9 1.7 2.0 3.4 1.9 4.1 0.4 2.6 8.9 3.7 0.3 1.4 0.4 8.4 3.4 2.2 7.3 0.2 1.2 4.7 0.5 1.3 0.9 1.9 4.0 1.9 8.1 7.2 2.1 1.6 0.5 0.5 6.4 1.2 1.5 1.1 0.0 3.1 3.0 2.2 0.3 8.0 2.8 4.9 1.2 3.0 7.6 3.7 0.6 2.2 0.7 2.6 2.0 3.0 1.6 5.7 6.7 1.8 9.7 1.8 0.2 5.2 5.7 3.4 1.6 5.4 8.8 1.8 1.7 0.8 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.7 1.8 1.1 2.1 1.7 1.8 1.4 1.8 1.4 1.3 2.5 1.7 1.3 6.4 24.6 11.8 7.0 1.9 3.3 3.3 6.2 0.5 7.6 9.9 1.5 7.2 15.6 20.2 0.0 6.7 4.7 2.8 0.0 3.3 0.6 9.5 6.8 1.5 4.2 1.7 5.3 0.5 4.4 4.2 12.8 11.1 3.8 10.3 0.4 5.7 3.0 0.0 2.3 3.0 2.0 0.8 1.6 0.6 1.8 3.3 0.0 1.9 2.3 1.4 3.1 11.1 3.2 1.8 2.4 1.9 5.1 3.5 1.5 1.5 10.1 1.3 0.0 2.1 2.6 0.9 2.1 4.9 1.7 3.8 7.0 2.1 4.4 2.9 PACRGL "C4orf28, MGC29898" ENSG00000163138 "Parkin coregulated like" Q8N7B6 4 20696282-20752907 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 211.7;Late spermatids: 88.4;Oligodendrocytes: 66.9;Spermatocytes: 90.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054666 Approved Nucleoplasm,Vesicles NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Vesicles" "HPA054666: AB_2682564" "unprognostic (1.32e-1)" "unprognostic (1.71e-1)" "unprognostic (6.90e-3)" "unprognostic (5.15e-2)" "unprognostic (1.15e-1)" "unprognostic (1.55e-2)" "unprognostic (1.09e-2)" "unprognostic (2.97e-1)" "unprognostic (4.55e-2)" "unprognostic (2.20e-2)" "unprognostic (5.08e-2)" "unprognostic (3.35e-2)" "unprognostic (1.25e-2)" "unprognostic (6.74e-3)" "unprognostic (3.63e-2)" "unprognostic (1.07e-2)" "prognostic favorable (4.85e-4)" 7.6 8.5 9.6 5.7 10.1 4.0 16.0 3.6 11.9 8.2 16.6 8.5 6.6 12.9 14.3 9.2 13.5 9.6 9.2 11.9 11.4 8.2 4.5 7.3 7.9 6.5 7.3 13.5 7.0 11.1 8.0 7.4 5.4 10.5 8.6 15.0 7.0 10.1 7.2 14.7 7.8 10.1 6.5 7.1 7.7 28.1 12.1 5.4 15.1 8.1 6.3 9.2 7.7 12.1 12.5 8.9 16.8 12.1 23.7 21.9 8.0 15.9 11.9 13.4 17.5 8.9 28.2 11.9 11.5 8.7 24.1 6.4 9.3 10.9 24.3 4.3 8.6 8.4 16.1 13.7 11.8 17.6 8.9 14.4 18.8 17.9 17.4 14.5 14.9 12.2 13.9 7.6 12.7 9.1 18.1 17.0 20.3 11.0 12.3 9.4 18.4 7.4 12.9 7.8 25.4 17.9 12.5 5.6 12.2 9.4 11.5 10.0 12.0 14.4 13.5 20.0 22.6 8.0 2.5 11.3 21.7 10.9 25.5 0.0 1.5 0.7 1.3 2.4 2.9 2.0 1.4 1.3 2.7 1.8 2.2 1.5 0.6 2.3 2.0 3.5 1.9 1.4 9.6 10.1 3.6 11.9 11.9 11.4 6.5 7.3 5.4 6.5 12.1 12.1 6.7 9.6 6.4 37.9 4.9 13.6 10.6 6.8 13.1 5.8 8.2 7.0 5.4 8.6 8.6 7.3 4.2 5.5 4.9 5.5 7.9 9.7 211.7 15.8 8.6 7.4 9.0 5.7 48.0 9.1 6.9 9.7 6.6 4.8 2.5 7.9 7.5 3.1 4.2 5.0 44.9 5.9 6.1 4.9 4.0 88.4 13.1 4.6 5.4 31.9 3.3 9.7 3.1 35.7 66.9 8.7 9.1 12.4 2.1 9.7 5.5 6.2 27.1 12.1 13.1 9.2 7.3 90.6 30.3 9.0 10.5 5.9 3.6 9.3 6.7 8.0 PADI2 "KIAA0994, PDI2" ENSG00000117115 "Peptidyl arginine deiminase 2" Q9Y2J8 1 17066761-17119451 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 240.6;skeletal muscle: 311.8;tongue: 492.3" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 95.9;Distal enterocytes: 178.7;Intestinal goblet cells: 77.3;Oligodendrocytes: 117.1;Paneth cells: 72.3" "Cancer enhanced" "Detected in many" "glioma: 24.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "eosinophil: 43.3;neutrophil: 100.6" "Lineage enriched" "Detected in many" 6 "granulocytes: 100.6" "Cell line enhanced" "Detected in some" "A549: 11.6;RPTEC TERT1: 33.1;SK-BR-3: 50.7;T-47d: 13.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047735 Enhanced NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA047735: AB_2680139" "unprognostic (2.61e-2)" "unprognostic (3.60e-2)" "unprognostic (8.94e-3)" "unprognostic (1.57e-1)" "unprognostic (2.33e-2)" "unprognostic (2.44e-1)" "unprognostic (1.49e-1)" "unprognostic (3.74e-3)" "unprognostic (2.78e-3)" "unprognostic (3.28e-3)" "unprognostic (1.29e-1)" "unprognostic (3.07e-1)" "unprognostic (2.87e-1)" "unprognostic (3.64e-2)" "unprognostic (3.15e-1)" "unprognostic (2.27e-1)" "unprognostic (5.91e-3)" 2.1 0.9 85.9 9.3 161.5 23.7 41.1 164.3 103.9 3.3 33.5 89.8 1.4 0.8 0.6 6.1 2.7 1.6 0.6 82.2 165.1 12.7 0.7 4.4 1.0 205.8 167.0 0.2 1.5 2.1 3.7 1.4 212.0 2.6 92.3 50.5 44.4 1.6 311.8 9.6 8.4 5.8 189.3 13.4 2.2 0.8 144.3 2.1 0.6 492.3 1.3 2.5 1.0 240.6 0.0 11.6 0.1 0.0 0.0 0.0 0.7 0.3 0.0 0.1 0.1 0.1 4.9 0.2 1.5 0.5 0.1 1.6 0.4 0.1 0.3 0.0 0.8 0.5 0.0 0.0 0.0 0.7 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.9 3.8 0.6 1.4 1.6 3.9 0.0 0.0 0.0 0.4 33.1 0.0 2.1 0.2 0.0 50.7 0.0 2.7 13.9 2.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 1.9 0.0 1.3 16.2 43.3 0.0 0.9 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.0 100.6 0.0 0.2 0.4 0.0 6.4 85.9 161.5 164.3 103.9 82.2 165.1 205.8 167.0 212.0 189.3 144.3 240.6 0.2 0.0 1.3 28.4 1.0 0.3 0.4 0.6 0.0 2.2 31.2 32.5 0.4 0.0 3.3 1.8 95.9 0.2 0.7 178.7 11.7 0.6 6.1 0.0 0.0 8.2 3.6 0.0 1.5 0.0 0.5 0.6 0.0 0.1 17.1 0.5 0.7 0.0 7.2 0.0 1.4 77.3 2.0 4.8 25.8 10.3 0.3 9.2 28.4 15.9 33.8 33.6 0.0 13.6 117.1 0.0 72.3 0.7 0.4 0.5 15.0 0.3 0.2 29.6 0.0 5.6 1.3 0.2 0.4 0.0 0.4 0.1 0.4 0.0 51.8 0.2 PAGE3 "CT16.6, GAGED1, PAGE-3" ENSG00000204279 "PAGE family member 3" Q5JUK9 X 55258412-55264846 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 49 "testis: 7.6" "Group enriched" "Detected in some" 63 "Early spermatids: 107.9;Late spermatids: 312.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045032, HPA062248" Uncertain Approved "Nucleoplasm,Nuclear speckles" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 31: Spermatids - Spermatogenesis" "Nuclear speckles" Nucleoplasm "HPA045032: , HPA062248: AB_2684725" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 107.9 0.0 0.0 0.1 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 312.1 0.9 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.6 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PANK2 "C20orf48, FLJ11729, HARP, HSS, NBIA1, PKAN" ENSG00000125779 "Pantothenate kinase 2" Q9BZ23 20 3888839-3929887 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Angiogenesis, Coenzyme A biosynthesis" "Kinase, Transferase" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008440 Approved Supported Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "HPA008440: AB_1079559" "unprognostic (4.50e-2)" "unprognostic (7.96e-3)" "unprognostic (2.26e-1)" "unprognostic (1.39e-2)" "unprognostic (1.68e-1)" "unprognostic (6.00e-2)" "prognostic unfavorable (1.20e-5)" "unprognostic (2.75e-1)" "unprognostic (3.39e-1)" "unprognostic (2.52e-1)" "unprognostic (3.02e-2)" "unprognostic (1.65e-1)" "unprognostic (6.01e-3)" "unprognostic (1.73e-2)" "unprognostic (2.18e-3)" "unprognostic (2.63e-1)" "unprognostic (1.81e-1)" 13.0 12.3 14.5 16.8 13.7 20.9 12.2 15.3 15.9 11.9 14.1 11.4 8.4 11.0 11.3 20.0 16.3 12.1 8.7 15.5 13.5 15.7 18.3 14.1 18.5 12.7 14.1 12.9 10.3 10.9 8.9 15.3 13.3 12.0 14.2 10.3 11.9 10.7 9.6 11.7 11.6 13.7 12.7 14.9 9.1 25.9 13.9 16.8 15.4 11.2 22.0 15.6 9.9 12.4 39.3 29.4 33.7 18.6 39.3 32.6 15.0 25.6 34.2 38.3 48.3 40.8 25.4 34.6 10.6 34.9 70.2 34.9 34.7 57.3 49.3 8.8 9.8 47.4 22.7 80.2 33.3 33.6 15.9 28.7 26.4 39.7 28.7 17.0 36.0 23.3 34.7 30.5 42.5 11.7 30.0 30.3 28.8 22.9 19.5 20.3 46.0 22.4 26.2 45.7 36.2 16.7 30.0 44.3 78.1 32.6 23.6 28.1 24.6 47.7 17.8 60.7 43.3 14.0 50.8 23.3 15.0 30.7 34.2 3.0 10.5 3.4 3.6 11.1 3.5 3.8 3.7 3.4 8.5 4.5 4.1 3.4 5.9 6.8 9.4 3.0 5.9 4.0 14.5 13.7 15.3 15.9 15.5 13.5 12.7 14.1 13.3 12.7 13.9 12.4 23.8 19.2 11.7 23.8 29.2 25.5 17.5 12.0 41.5 22.0 15.8 17.3 9.8 7.2 13.4 14.7 25.0 29.4 38.6 14.4 23.5 19.4 83.1 24.1 20.6 26.7 20.3 42.7 28.6 17.8 36.0 21.1 24.5 24.1 7.6 20.1 26.0 14.0 33.8 35.3 25.3 12.7 10.2 52.8 37.9 17.3 21.1 34.3 19.6 29.0 55.0 14.1 35.0 23.1 17.7 15.9 12.8 22.6 33.2 20.9 15.1 20.6 20.2 21.1 6.6 14.1 23.1 54.6 25.9 37.7 24.3 18.6 31.6 21.2 15.0 20.0 PAPOLB PAPT ENSG00000218823 "Poly(A) polymerase beta" Q9NRJ5 7 4857738-4862030 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 22 "testis: 29.9" "Cell type enhanced" "Detected in some" "Early spermatids: 94.8;Late spermatids: 89.7;Smooth muscle cells: 18.5;Spermatocytes: 37.4" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "cerebellum: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047285 Approved Nucleoplasm NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA047285: " "unprognostic (7.58e-2)" "unprognostic (1.25e-1)" "unprognostic (1.68e-2)" "unprognostic (1.78e-1)" 0.0 0.0 0.2 0.0 0.2 0.0 0.0 1.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 29.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 1.3 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.4 1.2 0.2 0.0 0.9 0.2 0.1 1.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 94.8 0.2 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 89.7 2.5 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.6 0.0 0.0 0.2 0.8 0.0 0.7 18.5 37.4 4.0 0.0 0.9 0.3 0.1 0.1 0.0 0.3 PAPSS2 ATPSK2 ENSG00000198682 "3'-phosphoadenosine 5'-phosphosulfate synthase 2" O95340 10 87659613-87747705 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Multifunctional enzyme, Nucleotidyltransferase, Transferase" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 135.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 240.4;Distal enterocytes: 202.4;Hepatocytes: 111.5;Proximal enterocytes: 181.3;Theca cells: 96.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "intermediate monocyte: 4.0;myeloid DC: 2.1;non-classical monocyte: 7.7" "Group enriched" "Detected in many" 7 "dendritic cells: 2.1;monocytes: 7.7" "Cell line enhanced" "Detected in many" "BJ: 189.8;fHDF/TERT166: 473.2;HHSteC: 196.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA071224, HPA075267" Enhanced Approved Mitochondria No No 16000 "Cluster 7: Monocytes - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 41: Macrophages - Immune response" Mitochondria "HPA071224: AB_2686366, HPA075267: " "unprognostic (3.98e-3)" "unprognostic (7.06e-2)" "unprognostic (4.95e-3)" "unprognostic (1.02e-1)" "unprognostic (2.67e-1)" "unprognostic (1.61e-2)" "unprognostic (4.96e-2)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.33e-6)" "unprognostic (3.50e-2)" "prognostic favorable (6.58e-4)" "unprognostic (1.14e-1)" "unprognostic (4.90e-2)" "unprognostic (6.72e-3)" "unprognostic (1.73e-1)" "prognostic unfavorable (3.21e-5)" "unprognostic (3.46e-3)" 33.3 135.2 6.3 26.6 7.0 2.0 20.9 6.2 9.5 17.8 6.2 79.9 29.5 8.5 3.1 10.2 12.4 20.7 11.6 5.8 6.2 23.8 77.0 70.4 11.0 6.9 6.6 27.5 26.1 2.1 3.0 58.5 7.5 6.7 64.3 2.3 16.4 3.4 4.7 3.5 61.8 16.7 6.8 8.5 9.2 11.7 8.0 3.0 21.3 8.7 14.8 16.6 11.5 7.2 19.9 20.0 6.4 0.3 129.4 164.8 0.3 189.8 157.7 110.4 79.9 1.0 4.1 0.1 9.8 473.2 3.5 8.5 13.9 13.3 125.2 0.2 10.0 8.8 13.4 0.1 196.5 0.2 3.8 58.7 0.3 63.7 5.2 135.6 94.2 1.4 0.0 89.4 79.2 74.1 0.1 0.7 7.4 4.8 24.1 0.4 0.1 0.4 117.5 8.7 0.9 1.6 92.5 3.3 1.1 12.6 13.5 5.3 120.0 38.2 22.5 131.5 13.9 0.3 1.0 0.3 18.3 0.2 0.2 0.0 1.1 0.0 0.0 4.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.6 0.0 7.7 0.0 0.0 0.8 6.3 7.0 6.2 9.5 5.8 6.2 6.9 6.6 7.5 6.8 8.0 7.2 49.5 240.4 38.2 3.6 2.6 2.3 0.9 18.0 1.8 0.2 11.5 4.7 4.4 8.6 13.8 9.2 0.0 0.5 0.8 202.4 13.7 6.4 1.2 2.6 18.7 23.2 12.6 5.2 22.2 30.2 0.8 36.1 15.3 11.6 0.0 20.3 36.0 111.5 11.5 0.0 27.6 26.5 4.1 29.8 50.7 0.8 17.4 51.0 1.8 30.0 5.2 1.3 0.0 21.6 1.0 19.4 46.1 5.3 3.1 2.1 181.3 9.8 3.4 0.0 13.1 1.0 20.4 1.2 0.7 1.1 1.3 1.4 1.7 96.4 74.3 1.1 PARD6A "PAR-6, PAR-6A, PAR6alpha, TAX40, TIP-40" ENSG00000102981 "Par-6 family cell polarity regulator alpha" Q9NPB6 16 67660946-67662774 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 38.5;testis: 42.9" "Cell type enriched" "Detected in many" 4 "Late spermatids: 266.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "REH: 27.9;RPMI-8226: 24.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009733, HPA041551" Approved Supported "Cell Junctions,Actin filaments,Cytosol" No No "Cluster 24: B-cells - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 25: Spermatids - Spermatogenesis" "Cell Junctions, Actin filaments" Cytosol "CAB009733: AB_2159676, HPA041551: AB_2677545" "prognostic favorable (5.40e-4)" "unprognostic (6.18e-2)" "unprognostic (1.77e-1)" "unprognostic (1.33e-2)" "unprognostic (7.63e-2)" "unprognostic (4.08e-3)" "unprognostic (1.23e-2)" "unprognostic (1.27e-1)" "unprognostic (6.59e-2)" "unprognostic (2.09e-1)" "unprognostic (1.98e-3)" "unprognostic (9.13e-2)" "prognostic favorable (3.08e-7)" "unprognostic (9.22e-3)" "unprognostic (6.69e-2)" "unprognostic (1.25e-1)" "unprognostic (1.39e-2)" 3.2 8.0 25.1 2.4 24.8 1.3 2.8 32.4 38.5 2.1 19.3 7.7 1.1 2.6 2.1 2.0 2.7 1.9 4.2 28.1 22.3 8.8 6.5 3.1 3.1 25.3 22.8 3.9 27.9 6.6 30.2 0.7 26.8 3.6 1.0 2.7 2.7 2.7 8.7 1.8 4.1 1.6 21.9 4.8 5.9 42.9 25.8 3.4 2.4 5.3 2.2 3.7 1.7 25.4 8.9 9.4 2.6 23.5 1.7 0.4 4.7 0.2 1.1 3.4 3.2 4.7 3.6 14.8 4.3 0.3 1.2 7.0 5.2 1.1 0.7 6.9 5.0 6.0 4.1 5.5 2.4 2.5 13.5 0.1 0.5 3.2 1.3 2.1 1.7 21.7 0.6 3.4 0.6 8.7 15.6 3.2 3.3 12.0 6.0 27.9 1.7 24.5 8.8 5.1 21.8 11.7 1.4 3.2 3.7 0.7 19.9 0.9 1.4 0.3 0.8 2.1 4.6 3.5 12.1 13.5 2.6 5.3 1.0 2.1 0.9 0.4 4.3 0.6 7.8 10.9 5.9 5.4 1.1 8.3 2.8 2.2 3.4 1.3 0.1 5.1 6.3 2.0 25.1 24.8 32.4 38.5 28.1 22.3 25.3 22.8 26.8 21.9 25.8 25.4 4.4 3.2 5.8 2.0 17.0 0.9 2.2 1.6 1.2 11.1 7.7 6.7 1.7 10.0 2.6 20.2 4.2 5.7 8.2 3.5 33.2 7.2 61.0 4.1 0.5 3.2 34.0 4.0 7.2 15.0 0.4 3.3 6.1 2.7 5.7 5.2 3.9 4.6 4.3 32.0 7.3 3.3 0.0 4.1 5.7 266.5 3.7 4.7 5.4 3.7 2.2 19.1 1.0 2.0 2.2 6.0 2.1 1.5 12.1 2.1 2.9 16.3 3.4 10.1 0.0 8.0 9.7 5.5 3.9 1.4 1.6 2.9 15.0 1.9 4.7 2.4 PARD6B PAR-6B ENSG00000124171 "Par-6 family cell polarity regulator beta" Q9BYG5 20 50731580-50756795 "Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 16.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 189.1;Glandular and luminal cells: 179.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 29.0;MCF7: 51.7;T-47d: 48.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013376 Uncertain Supported Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 6: T47d - Mammary gland" "Cluster 44: Endometrium - Transcription" Cytosol "HPA013376: AB_1854972" "unprognostic (1.13e-1)" "unprognostic (1.31e-1)" "unprognostic (1.50e-1)" "unprognostic (1.39e-3)" "unprognostic (2.56e-1)" "unprognostic (1.27e-1)" "prognostic unfavorable (1.02e-5)" "unprognostic (2.12e-1)" "unprognostic (1.37e-1)" "unprognostic (9.33e-2)" "prognostic unfavorable (8.38e-4)" "unprognostic (2.27e-1)" "prognostic favorable (6.38e-5)" "unprognostic (1.84e-2)" "unprognostic (1.97e-1)" "unprognostic (4.18e-2)" "unprognostic (1.07e-2)" 1.9 1.1 1.6 0.8 2.0 2.3 3.5 3.7 1.8 1.7 8.4 2.5 3.6 1.4 8.2 3.1 3.8 2.5 0.8 2.7 1.8 16.1 4.4 5.4 1.0 1.8 2.1 1.1 4.6 4.3 1.4 3.9 1.6 1.2 2.3 8.9 1.8 1.7 3.9 2.9 3.2 0.8 1.8 1.1 5.7 2.7 2.0 0.9 3.7 0.9 2.1 1.7 1.5 2.4 5.4 6.2 1.7 3.7 1.1 0.4 8.0 0.4 0.6 0.9 0.7 29.0 12.7 2.4 5.4 0.1 3.8 4.3 2.6 3.9 1.5 1.2 1.5 1.3 2.1 11.5 1.2 0.9 1.3 0.1 1.9 0.5 1.6 1.7 0.1 2.3 3.1 1.6 0.1 51.7 2.5 2.3 3.0 9.0 2.3 1.4 1.7 2.3 12.9 5.9 1.1 1.6 4.1 9.6 3.0 7.2 48.8 1.3 0.2 0.5 3.2 0.5 1.0 1.9 1.3 2.0 1.3 0.9 1.1 1.6 0.2 1.5 1.4 0.3 1.5 1.1 1.4 1.4 0.3 1.3 2.2 1.4 1.1 1.6 0.6 1.3 0.9 0.4 1.6 2.0 3.7 1.8 2.7 1.8 1.8 2.1 1.6 1.8 2.0 2.4 0.4 189.1 50.4 2.9 4.5 63.0 58.9 17.0 30.7 14.4 60.3 15.0 4.3 37.1 31.1 90.1 54.2 35.5 4.0 68.6 41.1 26.2 4.0 110.1 14.4 1.7 14.9 0.4 11.5 24.4 15.0 4.7 55.5 179.2 1.3 1.8 1.8 20.1 3.7 5.0 10.6 26.7 22.4 0.8 4.2 2.5 1.8 3.5 16.0 1.9 1.2 12.3 2.1 1.5 4.6 57.5 39.7 0.7 6.3 43.6 29.3 102.0 30.0 62.7 6.6 1.2 4.8 16.6 9.4 34.7 68.3 48.4 6.3 1.5 27.3 102.7 PAX4 MODY9 ENSG00000106331 "Paired box 4" O43316 7 127610292-127618142 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "intestine: 1.0" "Cell type enriched" "Detected in some" 7 "Enteroendocrine cells: 85.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 49 "SCLC-21H: 10.6" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "unprognostic (1.52e-1)" "unprognostic (9.71e-2)" "unprognostic (4.86e-3)" "unprognostic (1.21e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 1.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 2.9 0.0 0.0 0.0 85.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 11.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 PAX9 ENSG00000198807 "Paired box 9" P55771 14 36657568-36679362 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "esophagus: 81.0;lymphoid tissue: 20.5;parathyroid gland: 43.0;salivary gland: 51.8" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 45.3;Basal squamous epithelial cells: 174.8;Ionocytes: 40.7;Squamous epithelial cells: 172.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 12.3;HDLM-2: 58.3;PC-3: 18.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA001572, CAB016239" Enhanced Supported Nucleoplasm,Nucleoli NA NA "Cluster 35: T-regs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 44: HDLM-2 - Immune response" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoli Nucleoplasm "CAB016239: AB_2159984, HPA001572: " "unprognostic (3.09e-1)" "prognostic favorable (5.38e-4)" "unprognostic (1.56e-2)" "unprognostic (2.80e-2)" "unprognostic (1.40e-2)" "unprognostic (1.43e-2)" "unprognostic (5.93e-3)" "unprognostic (2.71e-3)" "unprognostic (2.96e-1)" "unprognostic (5.58e-2)" "unprognostic (2.41e-2)" "unprognostic (9.44e-2)" "unprognostic (2.31e-4)" "unprognostic (1.43e-1)" "unprognostic (1.20e-1)" "unprognostic (1.79e-1)" "unprognostic (1.17e-1)" 0.1 0.1 0.0 0.1 0.0 0.3 0.6 0.0 0.0 7.3 0.1 0.7 0.0 0.2 0.3 81.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.1 0.0 0.0 0.1 0.1 43.0 2.2 0.0 0.0 3.7 0.1 0.0 51.8 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.3 0.2 0.0 20.5 0.7 0.0 8.5 0.7 7.1 0.0 5.3 2.3 0.0 2.5 2.1 3.8 2.0 0.0 0.3 0.0 0.0 1.6 1.8 1.6 0.8 0.0 0.5 11.4 2.1 12.3 0.0 58.3 7.3 0.9 1.2 0.0 0.0 0.0 4.2 0.7 6.0 0.0 1.9 0.0 0.0 5.3 2.3 0.3 0.2 7.3 0.9 0.0 0.1 1.9 18.9 0.0 0.0 0.0 0.0 6.9 3.4 0.0 1.3 7.0 1.4 0.9 5.1 0.0 0.0 0.0 0.6 2.2 1.0 0.0 0.1 4.4 0.7 0.5 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 8.4 45.3 174.8 0.0 1.6 1.3 0.4 0.0 25.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.2 0.0 0.6 0.0 0.4 0.0 0.2 0.2 0.7 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 40.7 0.0 0.3 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.0 20.9 0.0 0.0 26.8 0.0 0.0 0.1 2.0 2.4 0.9 172.0 0.3 0.1 0.1 0.0 0.6 12.1 PAXIP1 "CAGF28, CAGF29, PAXIP1L, PTIP, TNRC2" ENSG00000157212 "PAX interacting protein 1" Q6ZW49 7 154943687-155003124 "Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 26.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "cerebellum: 12.0" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006694, HPA016950" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Vesicles" "HPA006694: AB_1855011, HPA016950: AB_2669489" "unprognostic (2.44e-2)" "unprognostic (1.28e-1)" "unprognostic (2.14e-2)" "unprognostic (2.66e-2)" "unprognostic (1.39e-1)" "unprognostic (1.63e-2)" "unprognostic (7.39e-3)" "unprognostic (2.65e-2)" "unprognostic (1.34e-3)" "unprognostic (1.19e-2)" "unprognostic (1.33e-1)" "unprognostic (2.36e-1)" "unprognostic (3.28e-2)" "unprognostic (4.99e-3)" "unprognostic (3.98e-1)" "unprognostic (2.44e-3)" "unprognostic (2.30e-1)" 4.3 3.9 2.3 5.8 2.5 9.8 5.4 12.0 2.6 4.8 2.7 4.9 4.8 4.6 4.8 5.4 4.2 4.4 3.9 2.3 2.4 4.6 5.7 4.2 8.8 2.8 2.6 5.7 4.4 6.2 3.8 6.1 2.9 4.4 4.9 3.9 5.7 3.6 5.9 6.5 5.7 3.7 2.5 5.6 5.2 8.7 2.6 26.6 5.5 4.6 6.0 5.3 4.7 2.8 17.7 14.2 18.4 31.2 7.8 6.5 16.4 7.6 8.0 10.3 11.9 15.7 13.6 22.9 9.4 9.1 21.3 13.6 23.7 12.1 12.7 23.0 18.4 17.4 10.7 13.6 5.5 23.9 22.3 6.3 9.0 10.3 4.2 5.8 9.9 22.8 24.3 15.1 10.4 24.3 51.1 19.9 29.8 17.1 9.5 28.8 18.7 24.8 10.7 14.6 14.6 9.4 20.3 14.9 9.5 16.6 11.4 20.1 5.1 8.6 1.5 12.3 18.6 15.2 9.5 31.0 21.1 27.7 23.6 0.2 0.9 0.5 0.9 1.1 1.4 0.5 1.5 1.1 1.0 0.9 2.4 0.7 0.5 1.3 1.3 1.2 1.2 0.9 2.3 2.5 12.0 2.6 2.3 2.4 2.8 2.6 2.9 2.5 2.6 2.8 5.2 6.4 6.3 18.9 5.8 6.4 5.1 4.7 4.0 18.9 8.9 6.6 6.9 7.2 7.1 9.2 10.4 9.0 3.8 6.8 5.9 3.9 2.3 5.5 6.9 5.2 2.4 10.3 21.4 3.3 8.0 6.9 5.6 6.5 2.5 8.8 5.0 9.2 4.4 3.3 24.2 8.4 2.0 6.1 7.1 2.8 8.7 4.8 3.6 15.9 6.3 8.0 7.2 27.2 27.4 4.4 4.3 9.4 4.9 8.0 5.2 4.2 4.3 12.3 0.0 11.1 5.1 22.6 18.7 8.9 7.0 6.2 4.9 6.3 9.8 4.5 PBXIP1 HPIP ENSG00000163346 "PBX homeobox interacting protein 1" Q96AQ6 1 154944076-154956123 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 176.0;Muller glia cells: 221.4;Theca cells: 153.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "granulocytes: 183.9;NK-cells: 56.9;T-cells: 197.4" "Cell line enriched" "Detected in all" 7 "Karpas-707: 1100.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006949 Approved Approved Vesicles,Cytosol NA NA 26000 "Cluster 13: T-cells - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" Vesicles Cytosol "HPA006949: AB_1079572" "unprognostic (6.17e-2)" "unprognostic (6.82e-2)" "prognostic unfavorable (2.73e-4)" "unprognostic (8.94e-2)" "unprognostic (2.16e-1)" "prognostic favorable (7.19e-4)" "unprognostic (1.62e-1)" "prognostic favorable (8.99e-4)" "unprognostic (1.21e-1)" "unprognostic (2.46e-1)" "prognostic favorable (2.64e-4)" "unprognostic (1.20e-2)" "prognostic favorable (9.22e-6)" "unprognostic (3.89e-1)" "unprognostic (4.15e-1)" "unprognostic (2.26e-1)" "unprognostic (1.26e-3)" 57.7 122.5 169.3 58.4 180.3 35.1 45.9 159.8 158.8 74.5 296.1 124.5 55.4 81.7 39.0 46.0 68.8 52.8 67.7 144.4 173.6 56.9 29.7 49.0 69.4 208.2 189.7 115.3 34.0 102.4 168.9 33.3 168.5 63.6 29.7 38.9 53.0 95.3 139.7 37.2 90.7 52.4 171.7 82.2 82.7 58.1 210.4 80.8 85.9 100.5 59.1 79.2 50.5 161.2 7.3 19.1 29.9 20.0 101.3 31.5 22.0 25.1 55.3 11.9 23.5 5.6 24.9 31.3 79.1 30.5 17.0 26.8 7.3 16.1 8.3 16.9 11.7 7.1 26.2 20.1 46.9 8.6 83.6 48.0 26.2 15.1 3.0 137.7 45.4 23.6 4.2 1100.7 29.8 11.1 17.6 27.5 11.4 19.3 14.4 20.2 43.1 69.7 32.9 14.1 4.9 37.6 32.5 10.2 26.7 56.1 31.0 36.6 42.9 11.8 8.6 7.6 7.8 149.4 133.9 7.7 42.2 12.4 9.6 129.4 10.3 183.9 41.9 14.8 116.3 36.0 112.4 66.9 9.1 23.6 72.9 46.2 95.2 56.9 29.7 16.2 197.4 61.5 169.3 180.3 159.8 158.8 144.4 173.6 208.2 189.7 168.5 171.7 210.4 161.2 24.5 67.3 77.9 56.8 43.0 10.1 24.0 22.4 13.1 23.8 17.6 19.7 38.5 38.6 31.1 42.3 16.7 19.5 48.2 21.0 0.0 46.0 142.1 12.9 25.9 23.8 83.7 22.3 1.5 18.5 24.0 35.9 19.9 10.5 51.9 30.3 28.9 19.4 14.7 1.7 1.2 20.9 69.2 20.2 13.8 176.0 64.3 16.8 26.6 7.5 25.5 221.4 39.1 3.5 1.6 22.4 29.3 129.1 49.0 10.5 56.0 9.9 23.9 8.8 52.6 83.9 50.6 8.8 13.9 6.3 11.5 27.1 116.2 153.3 15.9 13.9 PCARE "C2orf71, FLJ34931, RP54" ENSG00000179270 "Photoreceptor cilium actin regulator" A6NGG8 2 29060976-29074523 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Ciliopathy, Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "retina: 28.5" "Cell type enriched" "Detected in single" 20 "Cardiomyocytes: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 79: Retina - Phototransduction" "Cluster 43: Cardiomyocytes - Nuclear processes" "unprognostic (2.28e-3)" "unprognostic (1.23e-1)" "unprognostic (1.13e-1)" "unprognostic (3.15e-1)" "unprognostic (1.88e-1)" "unprognostic (5.88e-3)" "unprognostic (6.68e-3)" "unprognostic (1.21e-1)" "unprognostic (6.61e-2)" "unprognostic (3.81e-2)" "unprognostic (2.37e-1)" "unprognostic (2.08e-1)" "unprognostic (1.64e-1)" "unprognostic (2.28e-4)" 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.1 0.0 1.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.1 0.5 0.4 0.0 0.1 0.0 0.2 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 28.5 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.2 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.1 0.5 0.2 0.3 0.1 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PCDH1 pc42 ENSG00000156453 "Protocadherin 1" Q08174 5 141853090-141879246 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 61.5;Distal enterocytes: 66.4;Exocrine glandular cells: 46.3;Pancreatic endocrine cells: 65.2;Urothelial cells: 54.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 86.1;HaCaT: 108.0;HUVEC TERT2: 56.2;OE19: 77.8;RT4: 74.2;TIME: 74.5;WM-115: 52.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047720, HPA050538" Enhanced Approved "Nucleoplasm,Nucleoli,Cell Junctions" NA NA 2500000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cell Junctions" Nucleoli "HPA047720: AB_2680130, HPA050538: AB_2681162" "unprognostic (4.67e-2)" "unprognostic (1.79e-1)" "unprognostic (5.30e-2)" "unprognostic (4.61e-3)" "unprognostic (5.03e-2)" "unprognostic (4.16e-2)" "prognostic unfavorable (4.96e-5)" "unprognostic (1.98e-2)" "unprognostic (4.87e-2)" "unprognostic (1.31e-1)" "prognostic unfavorable (3.61e-4)" "unprognostic (2.43e-1)" "prognostic favorable (7.55e-5)" "unprognostic (2.05e-1)" "unprognostic (4.16e-2)" "unprognostic (3.13e-2)" "unprognostic (1.91e-1)" 24.0 4.0 11.7 7.7 15.9 1.2 22.8 3.3 15.1 11.6 0.0 23.1 21.4 9.2 6.4 41.7 9.1 6.6 19.3 17.0 2.3 21.3 19.3 27.7 2.0 0.0 0.8 2.5 13.8 3.8 6.5 19.2 0.0 10.8 14.3 3.4 28.8 11.2 8.2 27.4 17.1 7.2 1.1 1.8 23.6 1.1 2.7 1.0 12.6 11.1 9.1 9.8 19.2 5.7 18.9 1.0 7.7 8.5 0.3 0.0 5.5 0.2 0.2 0.1 0.0 4.5 86.1 0.1 43.7 0.6 1.0 108.0 9.9 7.9 0.0 0.1 0.3 0.0 0.4 0.1 6.9 0.0 0.3 0.0 17.8 0.1 1.2 18.1 56.2 0.0 0.1 9.2 0.0 15.1 0.3 0.0 32.5 77.8 14.6 0.3 0.1 13.2 6.3 74.2 0.9 1.8 0.5 23.3 20.0 21.6 18.8 0.4 74.5 0.1 0.7 0.1 6.9 0.0 0.1 0.2 0.5 0.0 52.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 11.7 15.9 3.3 15.1 17.0 2.3 0.0 0.8 0.0 1.1 2.7 5.7 61.5 0.0 5.3 3.6 0.2 1.0 12.0 4.6 0.0 9.6 9.5 4.7 4.4 20.0 8.6 12.9 0.0 0.7 2.0 66.4 3.9 15.3 1.3 10.1 2.1 34.2 7.7 2.7 12.3 46.3 0.3 2.6 21.9 21.3 0.0 0.0 7.5 30.1 0.2 26.9 6.1 21.3 12.2 1.4 2.3 2.5 0.6 0.5 0.0 6.5 0.0 4.8 7.2 5.5 7.2 65.2 30.3 0.4 1.4 25.8 36.4 5.2 7.1 0.5 13.1 0.9 18.5 0.3 0.2 7.4 2.6 20.1 0.9 0.5 18.9 54.5 PCDH10 "KIAA1400, OL-PCDH" ENSG00000138650 "Protocadherin 10" Q9P2E7 4 133149294-133208606 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 35.4;placenta: 25.9;prostate: 10.6;seminal vesicle: 17.3" "Cell type enhanced" "Detected in many" "Astrocytes: 58.1;Endometrial ciliated cells: 26.5;Excitatory neurons: 64.9;Glandular and luminal cells: 29.1;Inhibitory neurons: 57.7;Oligodendrocyte precursor cells: 46.8;Oligodendrocytes: 59.6" "Cancer enhanced" "Detected in many" "glioma: 8.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 11.5;HUVEC TERT2: 27.4;MOLT-4: 24.1;TIME: 55.4;U-138 MG: 14.5;U-251 MG: 12.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011220, HPA073462" Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" No NA 88000 "Cluster 65: Brain - Ion transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus" "Nucleoplasm, Vesicles" "HPA011220: AB_1855041, HPA073462: AB_2686605" "unprognostic (7.20e-2)" "unprognostic (8.74e-3)" "unprognostic (4.30e-2)" "unprognostic (8.12e-5)" "unprognostic (8.33e-2)" "unprognostic (3.20e-1)" "unprognostic (5.27e-3)" "unprognostic (4.51e-1)" "unprognostic (3.83e-2)" "unprognostic (1.15e-1)" "unprognostic (9.30e-3)" "unprognostic (8.72e-2)" "unprognostic (1.45e-1)" "unprognostic (8.68e-4)" "unprognostic (8.88e-2)" "unprognostic (6.31e-2)" "unprognostic (2.16e-4)" 0.5 5.1 20.5 0.2 35.4 0.0 0.1 0.9 23.9 1.5 0.0 0.5 0.1 1.6 0.5 0.3 1.2 0.5 1.2 19.6 15.2 2.1 0.1 0.7 0.0 7.7 24.9 2.3 0.2 0.0 1.4 25.9 11.3 10.6 0.2 3.0 0.5 17.3 0.0 0.0 0.4 0.7 3.7 0.0 0.4 1.4 16.8 0.1 0.5 0.0 0.0 1.8 2.8 19.1 0.0 0.7 8.7 0.0 0.3 0.0 0.0 8.6 4.6 0.7 0.4 0.0 0.0 0.0 0.2 0.3 0.2 0.0 0.0 0.0 0.9 0.0 4.9 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 11.5 27.4 0.0 0.3 0.0 4.2 0.0 24.1 0.0 0.0 0.0 0.3 0.5 0.3 0.5 0.0 0.4 0.0 0.2 0.0 0.0 0.1 0.5 0.0 0.3 55.4 14.5 0.0 0.1 12.9 0.0 0.0 0.0 1.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.5 35.4 0.9 23.9 19.6 15.2 7.7 24.9 11.3 3.7 16.8 19.1 1.4 0.0 0.6 58.1 0.0 0.1 0.5 0.1 1.2 15.0 1.2 2.7 2.3 0.0 0.7 0.0 0.0 0.8 0.0 0.9 1.9 0.0 5.6 26.5 4.6 4.0 0.0 0.0 64.9 0.0 0.9 15.5 0.0 29.1 0.0 5.0 0.0 0.0 1.8 0.0 57.7 0.2 0.0 0.0 0.0 1.7 0.0 0.5 0.0 6.5 0.0 8.6 0.0 46.8 59.6 0.0 0.0 0.4 0.0 0.1 0.0 0.3 0.1 2.7 0.0 4.3 11.5 17.4 0.9 0.0 0.3 2.9 0.2 3.9 0.1 0.4 PCDHA10 "CNR8, CNRN8, CNRS8, CRNR8, PCDH-ALPHA10" ENSG00000250120 "Protocadherin alpha 10" Q9Y5I2 5 140855883-141012347 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 6.3;pancreas: 4.1" "Cell type enhanced" "Detected in some" "Bipolar cells: 7.3;Cone photoreceptor cells: 8.4;Horizontal cells: 8.4" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "EFO-21: 16.2" "Low region specificity" "Detected in all" "Secreted - unknown location" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 38: EFO-21 - Unknown function" "Cluster 62: Horizontal cells - Visual perception" "unprognostic (4.24e-2)" "unprognostic (1.33e-1)" "unprognostic (1.73e-1)" "unprognostic (4.70e-2)" "unprognostic (4.19e-1)" "unprognostic (2.36e-1)" "unprognostic (6.46e-2)" "unprognostic (8.24e-2)" "unprognostic (8.10e-2)" "unprognostic (5.28e-2)" "unprognostic (2.65e-1)" "unprognostic (6.14e-3)" "unprognostic (1.93e-2)" "unprognostic (3.57e-3)" "unprognostic (5.21e-2)" "unprognostic (3.03e-1)" "unprognostic (1.10e-1)" 0.8 0.5 1.3 0.3 1.8 0.1 0.7 6.3 2.4 0.9 0.0 0.2 0.3 1.8 2.0 0.0 1.0 1.2 0.1 1.6 0.7 1.5 0.0 0.8 0.2 2.1 1.0 1.1 4.1 0.7 1.5 0.0 2.0 0.4 0.1 2.4 0.5 0.2 0.1 0.1 0.7 1.6 1.5 0.1 0.3 1.3 1.1 0.0 2.1 0.1 0.0 0.2 0.1 2.7 0.0 0.2 0.5 3.9 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 16.2 0.2 0.2 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.7 0.1 0.2 0.0 0.0 0.0 0.0 0.3 1.2 0.8 0.0 0.1 0.0 2.4 0.3 0.0 0.0 0.3 0.4 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.3 1.8 6.3 2.4 1.6 0.7 2.1 1.0 2.0 1.5 1.1 2.7 0.9 0.0 1.5 0.0 0.0 0.0 0.3 0.0 0.0 7.3 1.2 1.4 0.6 1.5 0.1 0.0 8.4 0.0 0.0 0.2 0.0 0.2 3.2 0.6 2.7 0.6 1.8 0.0 0.0 0.9 0.0 0.6 0.0 0.5 0.0 0.3 0.4 0.0 0.0 8.4 0.0 0.0 2.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.9 1.0 0.0 0.0 1.1 0.0 0.0 0.0 0.2 0.0 0.4 0.0 3.2 0.0 2.5 2.3 2.2 0.3 0.0 0.0 0.0 0.2 0.3 0.1 0.3 PCDHB12 PCDH-BETA12 ENSG00000120328 "Protocadherin beta 12" Q9Y5F1 5 141208697-141212571 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bipolar cells: 4.0;Endometrial stromal cells: 2.8;Fibroblasts: 2.8;Melanocytes: 3.6;Peritubular cells: 2.6;Skeletal myocytes: 2.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 2.7;ASC diff: 2.5;EFO-21: 3.0;RH-30: 3.2;U-2 OS: 2.3;U-2197: 2.4" HPA045042 Uncertain Approved "Plasma membrane" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA045042: AB_2679194" "unprognostic (1.43e-2)" "unprognostic (3.22e-3)" "unprognostic (4.18e-3)" "unprognostic (8.43e-2)" "unprognostic (3.95e-3)" "unprognostic (7.87e-3)" "unprognostic (1.46e-1)" "unprognostic (2.95e-2)" "unprognostic (3.63e-1)" "unprognostic (9.13e-3)" "unprognostic (4.86e-2)" "unprognostic (2.94e-2)" "unprognostic (4.37e-3)" "unprognostic (3.22e-3)" "unprognostic (4.97e-3)" "unprognostic (3.83e-2)" "unprognostic (6.41e-3)" 1.3 0.6 0.1 0.4 0.7 0.0 1.2 0.9 1.1 1.9 0.0 1.3 0.2 2.7 0.8 0.4 1.9 1.0 1.4 0.8 0.1 0.6 0.3 1.4 0.1 0.3 0.3 2.2 1.3 1.0 2.0 0.4 0.0 0.9 0.4 0.8 0.6 0.9 0.7 0.5 0.6 1.8 0.1 0.7 0.6 1.1 0.1 0.1 0.6 0.9 0.1 1.2 1.1 0.7 0.0 0.0 0.7 2.7 2.5 1.4 0.4 0.0 1.9 0.1 0.2 0.0 0.0 0.0 3.0 0.3 1.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.0 0.7 0.2 0.0 0.0 0.6 0.7 0.1 0.0 0.0 0.1 0.0 0.5 0.5 3.2 0.0 0.0 0.0 1.5 0.9 0.0 0.0 0.6 0.2 2.1 0.4 0.2 0.4 2.3 2.4 0.0 0.0 0.0 0.0 1.5 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.9 1.1 0.8 0.1 0.3 0.3 0.0 0.1 0.1 0.7 1.9 0.0 1.1 0.0 0.0 0.4 0.0 0.2 0.0 4.0 0.1 0.1 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.9 0.1 0.8 0.1 2.8 1.3 1.8 0.0 0.0 0.9 0.0 2.8 0.5 0.1 0.0 0.1 1.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.4 1.2 0.0 3.6 0.0 0.0 1.2 0.0 0.0 0.0 0.3 0.0 2.6 0.0 0.1 0.0 0.2 0.0 0.3 0.0 2.2 1.6 1.2 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.0 PCDHB15 PCDH-BETA15 ENSG00000113248 "Protocadherin beta 15" Q9Y5E8 5 141245395-141249365 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 4.3;Bipolar cells: 4.4;Early spermatids: 7.5;Endometrial stromal cells: 4.4;Fibroblasts: 3.7;Horizontal cells: 5.0;Skeletal myocytes: 4.2;Smooth muscle cells: 4.1;Spermatocytes: 4.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 6.2;LHCN-M2: 4.9;WM-115: 4.9" "Low region specificity" "Detected in all" "HPA007172, CAB026471, HPA074676" Uncertain Approved Mitochondria NA NA 250000 "Cluster 21: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 66: Spermatocytes - Spermatogenesis" Mitochondria "CAB026471: , HPA007172: AB_1079576, HPA074676: AB_2732263" "unprognostic (1.39e-1)" "unprognostic (1.58e-1)" "unprognostic (7.37e-3)" "unprognostic (1.75e-1)" "unprognostic (2.06e-2)" "unprognostic (6.19e-2)" "unprognostic (1.60e-1)" "unprognostic (4.12e-2)" "unprognostic (1.87e-2)" "unprognostic (7.58e-2)" "unprognostic (7.01e-2)" "unprognostic (6.00e-2)" "unprognostic (9.37e-2)" "unprognostic (1.08e-2)" "unprognostic (2.02e-1)" "unprognostic (1.08e-1)" "unprognostic (1.59e-1)" 3.8 1.4 1.9 2.5 2.1 0.0 2.6 4.2 2.4 6.4 0.0 3.8 0.5 6.8 2.5 1.4 5.0 2.1 4.4 1.8 1.6 2.1 1.1 3.7 0.7 3.0 2.5 7.4 3.3 0.8 3.5 1.5 2.0 2.4 0.9 2.0 1.7 2.0 1.3 1.3 1.8 4.1 2.5 2.5 2.1 5.4 2.3 0.3 2.7 1.4 0.5 3.6 3.2 2.4 0.2 0.0 6.2 0.7 1.5 1.6 0.1 0.4 1.2 0.1 0.3 0.0 0.3 0.0 1.2 0.9 1.6 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.9 0.2 0.2 0.0 0.0 0.7 1.3 0.0 0.2 1.6 0.3 0.0 0.0 1.0 4.9 0.0 0.0 0.1 1.5 0.0 0.0 0.2 0.7 0.0 0.4 0.1 0.3 0.8 0.3 0.3 1.6 0.8 0.3 0.0 0.0 0.6 0.6 2.2 0.0 0.1 0.8 0.0 0.8 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 2.1 4.2 2.4 1.8 1.6 3.0 2.5 2.0 2.5 2.3 2.4 4.3 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.0 4.4 0.2 0.3 1.4 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.2 7.5 0.2 4.4 2.4 0.0 0.0 0.0 1.5 0.0 3.7 0.5 0.2 0.0 0.6 1.4 0.0 0.1 5.0 0.0 0.0 0.0 0.0 0.0 2.3 0.6 0.0 1.8 0.0 0.0 1.3 0.0 0.0 0.0 0.9 0.1 3.4 0.0 0.1 0.0 0.7 0.1 0.8 0.0 4.2 4.1 4.8 0.7 0.2 0.6 0.0 0.1 0.5 0.1 0.3 PCDHB16 "KIAA1621, ME1, PCDH-BETA16, PCDH3X, PCDHB8a" ENSG00000272674 "Protocadherin beta 16" Q9NRJ7 5 141182387-141186226 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 14.9;Endometrial stromal cells: 10.0;Fibroblasts: 7.3;Horizontal cells: 8.4;Skeletal myocytes: 7.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 19.4;LHCN-M2: 10.5;U-138 MG: 39.3;U-2197: 11.1;U-87 MG: 9.9" "Low region specificity" "Detected in all" HPA014668 Approved "Vesicles,Plasma membrane" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "HPA014668: AB_1855055" "unprognostic (3.44e-3)" "unprognostic (4.03e-2)" "unprognostic (8.14e-2)" "unprognostic (8.60e-2)" "unprognostic (2.78e-2)" "unprognostic (1.36e-2)" "unprognostic (1.17e-1)" "unprognostic (4.03e-2)" "unprognostic (3.13e-2)" "unprognostic (7.55e-3)" "unprognostic (3.49e-2)" "unprognostic (9.57e-2)" "unprognostic (3.55e-2)" "unprognostic (7.49e-3)" "unprognostic (2.00e-2)" "unprognostic (7.92e-3)" "unprognostic (2.83e-3)" 3.1 1.9 1.2 1.2 0.9 0.2 2.4 2.1 1.8 2.6 0.0 1.6 0.5 4.5 4.8 0.7 2.2 2.0 2.5 1.6 0.8 2.0 1.0 2.4 0.6 2.0 1.0 6.7 1.9 4.3 2.3 1.2 1.2 1.7 0.9 2.2 1.8 0.9 1.0 1.3 0.9 2.7 1.5 1.1 0.9 1.4 1.3 0.4 1.7 3.3 0.2 1.6 1.5 2.2 0.1 0.3 1.0 19.4 7.8 5.2 0.6 0.8 3.8 0.0 0.3 0.1 0.3 0.0 5.0 0.9 2.1 0.2 0.7 0.0 0.0 0.1 0.0 0.0 0.4 0.4 0.0 0.1 0.2 0.1 0.1 0.0 0.0 3.3 0.1 0.2 0.1 2.0 10.5 0.4 0.0 0.1 1.5 0.0 0.2 0.1 2.8 0.0 0.6 0.2 0.7 2.6 0.3 0.6 3.9 0.5 7.9 0.0 0.6 39.3 1.7 11.1 2.7 0.1 0.1 0.0 9.9 0.1 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 1.2 0.9 2.1 1.8 1.6 0.8 2.0 1.0 1.2 1.5 1.3 2.2 6.4 3.2 1.5 0.0 0.0 0.8 0.1 1.0 0.0 14.9 1.2 2.4 1.9 5.7 0.6 1.8 0.0 0.0 0.0 0.0 1.9 0.8 1.2 0.6 10.0 4.8 1.8 0.0 0.0 4.7 0.0 7.3 0.5 0.4 0.0 0.2 2.2 0.1 0.1 8.4 0.0 0.0 4.1 0.3 0.9 1.5 4.7 0.2 0.0 0.0 0.0 5.4 0.0 0.0 0.0 1.7 0.0 5.7 0.1 0.1 0.0 0.7 0.2 1.6 0.0 7.6 5.9 2.9 0.3 0.5 1.4 0.0 0.2 0.4 0.0 0.0 PCDHB2 PCDH-BETA2 ENSG00000112852 "Protocadherin beta 2" Q9Y5E7 5 141094606-141098703 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 5.1;Endometrial stromal cells: 7.2;Spermatocytes: 9.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 23.7;AN3-CA: 51.0;EFO-21: 28.7;U-138 MG: 22.2" "Low region specificity" "Detected in many" HPA007548 Enhanced Approved Nucleoplasm NA NA "Cluster 71: Testis - DNA repair" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 36: Stromal cells - Cell proliferation" Nucleoplasm "HPA007548: AB_2667859" "unprognostic (2.94e-3)" "unprognostic (5.77e-2)" "unprognostic (4.57e-4)" "unprognostic (1.31e-1)" "unprognostic (3.03e-3)" "unprognostic (7.01e-2)" "unprognostic (5.52e-2)" "unprognostic (2.24e-1)" "unprognostic (3.99e-1)" "unprognostic (2.19e-2)" "unprognostic (1.16e-1)" "unprognostic (2.31e-1)" "prognostic unfavorable (6.99e-4)" "unprognostic (2.13e-3)" "unprognostic (6.70e-2)" "unprognostic (1.37e-1)" "prognostic unfavorable (4.84e-4)" 2.7 0.9 0.7 0.4 1.2 0.1 2.6 0.9 2.6 1.8 0.0 2.3 0.6 2.3 0.6 0.9 1.3 1.4 1.9 2.4 1.0 1.0 0.2 2.2 0.2 0.9 0.9 1.7 1.0 0.1 1.8 0.7 0.7 1.5 0.9 1.4 1.7 0.4 1.0 2.0 0.9 1.4 0.9 0.6 0.8 5.5 0.8 0.2 1.3 1.3 0.1 1.2 1.3 1.8 0.4 3.4 23.7 51.0 6.7 3.1 10.8 0.9 3.7 0.0 0.0 0.6 0.2 0.9 28.7 1.7 5.6 0.0 1.2 0.3 0.0 0.3 0.8 0.0 0.1 6.9 0.0 0.0 2.4 1.6 0.0 0.0 0.4 1.0 0.5 2.9 0.8 0.7 7.1 0.2 6.9 0.0 10.5 0.3 6.7 0.0 17.6 0.2 2.6 0.0 13.1 3.6 0.0 3.4 7.6 13.2 14.6 4.3 2.8 22.2 6.6 10.5 3.4 0.3 0.1 0.2 4.8 0.2 13.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.2 0.9 2.6 2.4 1.0 0.9 0.9 0.7 0.9 0.8 1.8 5.1 0.0 0.5 0.0 0.0 0.8 1.1 0.6 4.0 3.1 1.8 1.0 0.4 0.0 0.7 0.0 0.0 0.0 0.0 0.2 0.0 0.4 1.6 2.1 7.2 2.5 1.2 0.0 0.0 0.4 0.0 3.7 0.5 1.3 0.0 0.7 0.0 0.0 0.1 1.7 0.0 0.2 0.0 0.0 0.3 1.0 1.2 0.1 3.6 0.0 0.1 1.9 0.0 0.0 0.0 0.2 0.1 1.5 0.0 0.8 0.0 0.3 0.8 1.4 0.0 3.0 1.9 9.9 4.0 0.7 0.4 0.0 0.1 0.1 0.1 0.7 PCDHB3 PCDH-BETA3 ENSG00000113205 "Protocadherin beta 3" Q9Y5E6 5 141100473-141103827 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 2.8;Cone photoreceptor cells: 2.1;Endometrial stromal cells: 2.6;Horizontal cells: 8.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 11.3;HAP1: 3.5;SH-SY5Y: 15.2;U-138 MG: 5.3" "Low region specificity" "Detected in all" HPA050296 Uncertain Supported Vesicles NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA050296: AB_2681078" "unprognostic (2.72e-2)" "unprognostic (7.47e-4)" "unprognostic (1.22e-1)" "unprognostic (1.95e-4)" "unprognostic (9.34e-3)" "unprognostic (3.42e-2)" "unprognostic (2.29e-2)" "unprognostic (3.17e-1)" "unprognostic (1.37e-1)" "unprognostic (3.34e-1)" "unprognostic (8.52e-3)" "unprognostic (3.45e-2)" "unprognostic (1.82e-2)" "unprognostic (2.37e-3)" "unprognostic (1.24e-1)" "unprognostic (1.82e-2)" "unprognostic (5.18e-4)" 1.8 1.2 0.4 0.7 1.1 0.0 1.7 0.6 1.5 1.2 0.0 0.9 0.3 1.5 0.7 0.3 0.9 0.8 1.1 1.0 0.2 1.1 0.1 1.1 0.1 0.3 0.5 1.6 1.2 1.7 1.8 0.4 0.1 1.4 0.5 1.0 0.7 0.5 0.7 0.7 0.5 1.0 0.2 0.4 0.5 3.6 0.6 0.0 0.7 0.9 0.1 0.8 0.9 0.8 0.0 0.0 1.1 3.1 1.9 0.3 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 11.3 0.2 1.7 0.0 3.5 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 1.3 0.0 0.5 0.0 0.2 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.6 15.2 0.0 0.1 0.0 0.5 1.9 0.1 0.0 5.3 0.7 0.5 0.3 0.3 0.0 0.0 0.3 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.1 0.6 1.5 1.0 0.2 0.3 0.5 0.1 0.2 0.6 0.8 2.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.9 0.8 0.3 0.0 0.0 0.0 2.1 0.0 0.0 0.0 1.9 0.3 0.8 0.4 2.6 1.1 0.0 0.0 0.0 0.2 0.0 1.4 0.0 0.2 0.0 0.0 1.8 0.0 0.0 8.4 0.0 0.2 0.0 0.0 0.3 0.0 0.6 0.0 1.8 0.0 0.0 0.9 0.0 0.0 0.0 0.3 0.0 0.7 0.0 0.5 0.0 0.1 0.0 0.3 0.0 1.7 1.1 1.8 0.7 0.1 0.3 0.0 0.0 0.4 0.0 0.3 PCLAF "KIAA0101, NS5ATP9, OEATC-1, p15(PAF), PAF15" ENSG00000166803 "PCNA clamp associated factor" Q15004 15 64364304-64387687 "Predicted intracellular proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 128.6;lymphoid tissue: 73.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 82.2;Extravillous trophoblasts: 160.2;Granulosa cells: 48.8;Hofbauer cells: 110.2;Syncytiotrophoblasts: 42.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 4 "T-reg: 23.6" "Lineage enriched" "Detected in many" 4 "T-cells: 23.6" "Low cell line specificity" "Detected in all" HPA047929 Supported Centrosome NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 24: NB-4 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" Centrosome "HPA047929: AB_2680215" "unprognostic (5.34e-2)" "unprognostic (1.36e-3)" "unprognostic (9.39e-2)" "unprognostic (1.28e-1)" "unprognostic (4.16e-1)" "unprognostic (2.22e-1)" "prognostic unfavorable (3.26e-5)" "unprognostic (4.38e-3)" "unprognostic (1.91e-3)" "unprognostic (7.26e-2)" "unprognostic (2.56e-3)" "unprognostic (9.65e-2)" "prognostic unfavorable (9.77e-15)" "unprognostic (5.59e-2)" "unprognostic (2.05e-1)" "unprognostic (8.65e-2)" "unprognostic (3.22e-1)" 2.1 1.4 0.9 22.9 1.0 128.6 3.9 1.4 1.1 1.7 0.8 19.0 14.7 4.5 1.2 15.2 1.3 2.5 0.4 0.9 0.6 1.2 3.6 2.5 49.5 1.0 0.8 0.4 1.9 0.8 0.5 8.7 0.9 2.0 22.6 0.3 2.3 0.3 0.4 6.7 15.8 5.0 0.5 7.4 8.1 1.1 1.0 73.8 2.2 0.1 47.1 7.9 4.9 1.9 212.6 165.8 154.4 140.8 15.9 60.9 134.4 146.2 84.8 185.4 276.4 198.4 202.1 343.7 46.4 57.4 64.8 153.6 340.7 83.1 235.3 192.5 124.8 352.5 202.5 209.8 1.5 285.3 153.8 20.0 7.9 156.4 31.9 52.3 168.9 175.9 201.3 104.4 248.1 187.8 268.0 605.5 73.9 179.9 73.4 416.6 353.8 247.1 115.9 200.2 19.1 86.7 112.8 105.2 69.3 78.9 153.8 365.3 36.3 158.4 308.6 177.8 386.7 65.5 223.4 229.0 67.7 512.9 108.5 2.4 0.3 0.9 1.4 0.2 0.2 2.0 4.4 4.2 2.8 0.6 0.5 1.0 2.7 5.7 0.4 0.3 23.6 2.3 0.9 1.0 1.4 1.1 0.9 0.6 1.0 0.8 0.9 0.5 1.0 1.9 0.5 9.6 11.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 27.5 25.5 0.0 0.0 5.0 1.8 0.0 82.2 8.3 0.0 1.9 6.5 0.0 18.6 10.4 8.5 0.0 0.0 0.0 3.0 160.2 25.4 0.0 13.8 3.8 48.8 0.0 0.0 110.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.7 0.0 0.0 1.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 4.3 0.0 0.0 3.0 3.6 0.0 0.0 0.0 20.6 0.0 0.0 0.0 0.0 42.1 5.8 7.6 0.0 0.0 PCP4L1 IQM1 ENSG00000248485 "Purkinje cell protein 4 like 1" A6NKN8 1 161258745-161285450 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 71.7;pituitary gland: 84.3" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 35.8;Bipolar cells: 82.8;Inhibitory neurons: 34.0;Sertoli cells: 19.7;Squamous epithelial cells: 23.5;Urothelial cells: 39.9" "Cancer enhanced" "Detected in many" "urothelial cancer: 21.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "RT4: 13.8;T-47d: 8.9" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "olfactory bulb: 206.6" HPA052833 Enhanced Supported Approved Nucleoplasm,Mitochondria NA NA "Cluster 35: T-regs - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 15: RT4 - Unknown function" "Cluster 56: Bipolar cells - Visual perception" "Nucleoplasm, Mitochondria" "HPA052833: AB_2681968" "unprognostic (1.81e-2)" "unprognostic (9.39e-2)" "unprognostic (5.25e-2)" "unprognostic (2.07e-1)" "unprognostic (3.03e-2)" "unprognostic (1.87e-2)" "unprognostic (2.51e-1)" "prognostic favorable (8.10e-5)" "unprognostic (2.39e-1)" "unprognostic (1.92e-1)" "unprognostic (4.93e-2)" "unprognostic (7.37e-2)" "unprognostic (3.63e-5)" "unprognostic (4.81e-2)" "unprognostic (1.25e-1)" "unprognostic (2.09e-1)" "unprognostic (6.15e-2)" 2.7 0.4 14.1 0.8 71.7 0.1 1.8 19.6 33.2 4.0 0.9 5.6 1.7 1.8 2.6 18.8 2.1 2.0 0.8 6.8 14.7 0.9 4.0 4.6 0.2 39.7 23.3 2.2 0.5 0.4 84.3 0.3 39.8 11.0 2.5 39.2 1.9 16.4 0.4 5.6 2.8 6.6 28.1 0.3 2.0 1.8 15.2 2.0 0.7 1.5 2.6 35.6 17.1 13.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 1.7 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.3 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.1 0.0 0.1 0.0 13.8 1.9 0.0 0.0 0.2 0.0 0.2 8.9 0.3 0.2 0.0 0.0 0.0 0.0 0.8 0.9 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 14.1 71.7 19.6 33.2 6.8 14.7 39.7 23.3 39.8 28.1 15.2 13.9 0.0 3.2 6.4 2.0 0.0 0.0 35.8 8.3 12.5 82.8 3.2 1.0 0.2 0.0 7.6 0.0 6.2 0.4 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.3 0.0 0.0 3.1 1.3 1.9 0.2 4.6 0.3 1.3 0.0 0.0 0.9 0.1 0.0 34.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.8 0.0 3.5 0.0 5.0 1.4 0.2 0.0 1.9 0.0 2.5 0.0 0.6 0.9 5.9 19.7 0.0 10.0 1.3 1.5 23.5 0.3 1.8 0.0 0.0 0.0 39.9 PCSK7 "LPC, PC7, PC8, SPC7" ENSG00000160613 "Proprotein convertase subtilisin/kexin type 7" Q16549 11 117204337-117232525 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "NK-cells: 310.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 8400 "Cluster 15: NK-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (7.11e-2)" "unprognostic (2.90e-2)" "unprognostic (8.33e-3)" "unprognostic (4.24e-2)" "unprognostic (1.32e-1)" "unprognostic (2.77e-2)" "unprognostic (1.56e-1)" "unprognostic (2.60e-1)" "unprognostic (1.96e-1)" "unprognostic (2.41e-1)" "unprognostic (8.80e-2)" "unprognostic (1.09e-1)" "unprognostic (1.02e-1)" "unprognostic (1.51e-1)" "unprognostic (1.06e-1)" "unprognostic (1.00e-1)" "unprognostic (3.03e-2)" 31.8 16.4 16.4 27.9 17.6 25.7 24.0 15.9 20.9 27.5 16.7 69.5 29.2 72.4 7.6 24.0 35.7 12.9 20.1 19.9 16.6 15.7 19.6 25.6 31.6 18.1 17.0 17.5 29.7 11.8 16.6 13.5 18.0 35.4 37.5 10.0 15.9 11.2 15.6 20.7 35.4 13.5 15.7 30.7 45.1 12.5 18.3 25.0 18.1 10.7 29.2 39.4 22.2 20.2 14.6 27.5 19.1 21.4 23.3 19.0 15.0 48.5 22.2 24.1 23.9 38.3 82.6 24.8 33.5 38.6 31.1 48.0 25.2 34.7 15.5 34.2 24.2 36.7 40.7 17.5 26.1 23.2 49.4 32.9 22.5 33.0 26.4 12.4 41.2 28.0 22.5 22.0 34.8 19.0 31.5 24.3 17.6 63.4 28.1 19.1 16.9 29.5 30.1 33.7 24.9 32.3 39.6 51.1 7.5 14.8 32.3 18.6 36.4 36.4 16.4 31.5 34.3 13.4 8.7 14.0 18.6 33.1 33.3 7.9 7.1 9.0 38.1 9.8 33.0 23.5 29.7 35.6 7.6 18.5 20.8 24.7 5.3 41.0 11.5 8.8 42.8 20.6 16.4 17.6 15.9 20.9 19.9 16.6 18.1 17.0 18.0 15.7 18.3 20.2 47.4 48.1 36.2 44.4 93.3 70.1 50.0 35.2 19.4 124.1 31.2 23.5 8.1 35.8 42.5 47.8 246.0 50.7 97.4 204.9 5.9 27.4 6.4 21.0 40.3 47.5 62.4 27.4 47.2 54.5 39.0 38.5 110.6 36.5 34.1 30.2 77.4 27.8 32.4 87.5 41.4 91.2 24.4 60.6 83.9 7.5 33.5 39.2 53.4 25.3 54.6 21.8 310.0 48.2 62.0 73.7 132.2 39.9 58.7 39.0 98.2 9.2 22.9 178.8 72.3 87.5 107.7 64.4 24.5 27.4 94.3 62.5 127.3 42.7 110.3 53.3 PDE2A ENSG00000186642 "Phosphodiesterase 2A" O00408 11 72576141-72674591 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 197.0" "Group enriched" "Detected in many" 6 "Adipocytes: 114.9;Endothelial cells: 58.5;Enteroendocrine cells: 34.4;Excitatory neurons: 70.1;Hepatic stellate cells: 118.2;Inhibitory neurons: 35.6" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "amygdala: 75.1;basal ganglia: 84.7;cerebral cortex: 102.1;hippocampal formation: 84.4;white matter: 48.3" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 2.8;T-cells: 7.3" "Cell line enriched" "Detected in some" 8 "HeLa: 513.6" "Low region specificity" "Detected in some" "Group enriched" "Detected in all" 5 "amygdala: 83.5;basal ganglia: 146.9;cerebral cortex: 90.5;hippocampal formation: 94.0" "CAB009752, HPA031192" Enhanced Supported Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 64: Macrophages - Immune response" "Cluster 20: HeLa - Mitochondria" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "CAB009752: AB_2268159, HPA031192: AB_2673781" "unprognostic (1.92e-1)" "unprognostic (1.52e-3)" "unprognostic (4.58e-2)" "unprognostic (1.49e-1)" "unprognostic (1.26e-1)" "unprognostic (2.50e-1)" "prognostic favorable (1.76e-6)" "unprognostic (3.06e-2)" "unprognostic (1.35e-1)" "unprognostic (3.01e-3)" "unprognostic (3.13e-3)" "unprognostic (1.50e-2)" "unprognostic (1.77e-2)" "unprognostic (2.85e-3)" "unprognostic (6.31e-2)" "unprognostic (7.72e-2)" "unprognostic (7.96e-4)" 89.2 44.1 75.1 5.1 84.7 4.7 83.6 0.0 102.1 38.1 0.0 34.6 6.0 27.2 8.3 18.6 39.3 22.7 41.1 84.4 7.0 32.5 19.4 12.6 6.7 6.4 5.1 11.6 6.9 5.5 11.8 12.0 10.1 20.7 8.9 3.0 9.2 10.7 16.8 18.1 18.7 18.5 0.0 197.0 17.1 7.4 17.9 3.8 24.1 28.9 3.5 28.8 27.1 48.3 0.3 0.2 0.7 0.2 0.2 0.1 0.3 0.1 0.2 0.2 0.4 0.4 2.5 0.8 12.2 0.2 1.9 0.2 0.9 0.1 0.1 0.1 0.1 0.0 513.6 0.8 0.9 0.0 7.8 0.1 1.1 2.7 20.5 1.1 11.3 0.5 0.8 0.9 0.1 0.0 0.2 0.2 7.4 0.2 14.0 0.0 0.2 1.4 0.1 0.3 44.5 2.4 0.4 0.2 2.2 0.7 0.3 0.1 65.2 0.1 9.4 3.5 0.4 0.4 0.2 0.1 3.9 0.1 0.6 0.0 0.6 0.0 7.3 0.8 4.2 2.8 4.3 4.3 1.0 1.8 2.7 2.3 0.1 0.0 0.4 0.0 1.8 1.5 75.1 84.7 0.0 102.1 84.4 7.0 6.4 5.1 10.1 0.0 17.9 48.3 114.9 0.0 0.5 2.0 0.7 2.5 0.1 0.0 0.0 4.9 0.6 1.0 7.8 0.0 0.0 0.0 0.0 0.0 1.6 0.2 0.0 0.0 0.6 0.0 0.1 58.5 34.4 5.3 70.1 0.0 0.3 2.1 0.0 0.1 1.3 0.1 118.2 2.1 0.5 1.7 35.6 1.2 0.0 9.4 8.2 2.5 0.3 4.9 1.8 11.2 0.0 0.0 0.0 9.0 5.7 0.1 0.0 0.4 1.5 0.1 0.0 0.1 0.0 0.4 0.0 1.8 6.6 4.8 2.5 0.5 2.8 0.0 0.6 0.2 0.1 0.3 PDE6D JBTS22 ENSG00000156973 "Phosphodiesterase 6D" O43924 2 231732433-231786272 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Sensory transduction, Vision" "Ciliopathy, Joubert syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 211.9;Late spermatids: 147.9;Spermatocytes: 236.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037433, HPA037434" Uncertain NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA037433: AB_2675475, HPA037434: AB_10672490" "unprognostic (1.95e-1)" "unprognostic (2.33e-2)" "unprognostic (1.22e-1)" "unprognostic (7.72e-3)" "unprognostic (7.07e-2)" "unprognostic (5.41e-2)" "unprognostic (1.15e-1)" "unprognostic (9.48e-2)" "unprognostic (3.91e-1)" "unprognostic (1.41e-1)" "unprognostic (1.69e-1)" "unprognostic (4.75e-2)" "prognostic unfavorable (4.02e-5)" "unprognostic (1.11e-2)" "unprognostic (1.80e-2)" "unprognostic (1.46e-1)" "prognostic favorable (4.97e-4)" 16.8 28.1 43.4 16.2 47.3 14.6 16.3 47.4 50.7 19.2 38.0 19.6 13.4 17.6 14.9 16.3 15.5 14.2 19.3 44.4 45.7 19.5 15.4 15.2 23.3 45.6 46.0 13.4 13.2 23.5 25.0 23.0 45.7 13.7 17.6 69.6 14.2 17.6 13.7 16.4 15.7 22.0 46.5 18.8 16.2 27.8 45.8 32.4 14.0 16.7 24.0 17.9 16.4 49.6 26.3 20.3 37.0 28.2 43.7 36.1 15.7 27.0 44.6 40.8 56.9 8.1 24.5 21.4 22.7 23.2 74.9 20.4 22.3 30.2 52.6 63.5 26.4 31.2 12.4 13.0 20.2 20.6 17.2 25.5 26.4 39.8 30.4 27.5 44.1 68.3 9.1 23.5 27.5 52.0 67.7 64.4 28.6 39.6 28.1 45.7 17.0 32.9 42.8 19.5 36.4 32.6 23.0 19.4 46.3 36.1 17.5 43.0 19.5 26.5 7.3 57.9 21.4 57.9 26.3 52.6 27.4 38.6 42.5 84.4 48.2 68.4 46.3 48.7 36.3 50.4 46.0 47.3 49.3 55.5 31.7 44.3 42.0 34.4 64.9 55.8 84.4 43.1 43.4 47.3 47.4 50.7 44.4 45.7 45.6 46.0 45.7 46.5 45.8 49.6 20.8 0.0 8.7 18.3 19.5 13.8 12.4 23.6 21.1 14.7 13.3 17.7 13.1 12.8 15.8 12.9 16.7 16.4 18.2 10.2 25.4 23.1 211.9 6.8 9.2 19.6 17.4 15.8 13.4 23.9 21.9 14.7 13.3 6.5 14.5 7.3 19.2 5.0 18.9 11.8 18.1 10.0 14.2 14.4 15.1 147.9 13.1 17.5 23.2 16.9 24.6 22.0 17.5 48.7 34.0 26.0 14.9 12.4 17.0 10.5 11.2 18.4 11.8 29.0 19.7 10.7 24.9 236.8 65.1 20.3 14.2 13.5 18.5 11.5 10.5 11.0 PDSS1 "COQ1, COQ1A, TPRT, TPT" ENSG00000148459 "Decaprenyl diphosphate synthase subunit 1" Q5T2R2 10 26697701-26746798 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Isoprene biosynthesis, Ubiquinone biosynthesis" Transferase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 19.1;lymphoid tissue: 13.8" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 32.5;Proximal enterocytes: 29.8;Undifferentiated cells: 29.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038032, HPA042741" Uncertain Approved Cytosol NA NA "Cluster 24: B-cells - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA038032: AB_10670650, HPA042741: AB_2678139" "unprognostic (1.41e-2)" "unprognostic (3.92e-1)" "unprognostic (8.92e-3)" "prognostic unfavorable (1.66e-4)" "unprognostic (6.79e-3)" "unprognostic (5.43e-2)" "prognostic unfavorable (1.25e-5)" "unprognostic (2.47e-2)" "unprognostic (9.43e-2)" "unprognostic (2.33e-2)" "unprognostic (2.20e-1)" "unprognostic (4.11e-2)" "unprognostic (2.99e-3)" "unprognostic (2.93e-3)" "unprognostic (8.85e-2)" "unprognostic (9.83e-2)" "unprognostic (6.36e-2)" 2.1 1.4 0.8 5.3 0.9 5.8 2.3 2.6 1.4 1.8 0.6 14.1 19.1 1.9 1.3 4.3 1.5 1.6 2.8 0.8 0.8 6.2 3.6 2.2 4.0 0.8 0.9 1.7 1.3 2.2 0.8 2.4 0.9 1.5 15.1 1.9 1.8 1.3 5.7 1.4 15.3 2.9 0.8 1.8 2.8 2.8 0.9 13.8 1.2 9.5 4.7 3.1 2.2 1.1 15.6 11.8 8.9 16.3 2.9 5.4 12.2 14.0 3.6 20.0 13.7 18.3 8.4 35.0 7.2 7.0 7.6 19.2 28.6 21.8 16.7 14.7 23.6 30.4 9.9 13.6 4.3 20.3 11.6 6.8 9.2 19.0 5.0 3.5 10.7 22.8 28.4 9.3 14.4 24.9 64.6 14.7 17.9 24.9 11.3 29.6 25.1 25.5 12.0 7.3 25.7 15.8 13.5 27.6 15.9 9.2 9.9 23.7 6.8 11.1 17.9 22.9 22.5 3.6 14.1 25.6 10.9 51.3 8.7 0.0 2.8 0.5 0.4 2.3 1.0 0.2 0.8 0.6 2.6 2.4 1.6 0.7 0.1 0.4 1.2 0.7 0.0 0.7 0.8 0.9 2.6 1.4 0.8 0.8 0.8 0.9 0.9 0.8 0.9 1.1 3.6 0.0 0.0 18.9 4.8 6.9 3.6 5.7 8.0 2.9 4.4 5.1 2.2 5.7 3.9 3.7 4.2 7.7 4.9 11.7 7.9 6.1 12.0 2.1 3.8 2.7 10.8 8.4 16.9 3.9 12.4 3.4 10.2 3.3 0.0 3.7 1.8 4.5 8.8 1.7 32.5 13.0 6.1 5.3 2.7 4.1 2.1 7.7 1.8 5.6 6.2 1.2 1.0 6.6 6.5 5.6 9.8 2.6 9.1 3.7 29.8 26.3 2.1 4.9 0.0 4.1 6.5 12.5 9.4 13.6 3.1 6.3 4.8 4.6 29.8 3.3 PEA15 "HMAT1, HUMMAT1H, MAT1, MAT1H, PEA-15, PED, PED-PEA15, PED/PEA15" ENSG00000162734 "Proliferation and apoptosis adaptor protein 15" Q15121 1 160205380-160215376 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, Sugar transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1106.4" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 246.3;monocytes: 267.6;Muller glia cells: 315.8" "Cancer enhanced" "Detected in all" "glioma: 466.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "intermediate monocyte: 78.2" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028356, HPA070820" Enhanced Supported Nucleoplasm,Cytosol NA NA 300000 "Cluster 7: Monocytes - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 3: Monocytes - Immune response regulation" Cytosol Nucleoplasm "HPA028356: AB_10602814, HPA070820: AB_2732166" "unprognostic (1.29e-1)" "unprognostic (4.78e-2)" "unprognostic (1.05e-1)" "unprognostic (1.57e-1)" "unprognostic (2.53e-1)" "unprognostic (1.64e-2)" "unprognostic (1.99e-3)" "unprognostic (6.10e-2)" "unprognostic (4.57e-1)" "unprognostic (1.25e-1)" "unprognostic (6.31e-2)" "unprognostic (4.07e-2)" "prognostic unfavorable (6.53e-7)" "unprognostic (2.60e-2)" "unprognostic (1.39e-1)" "unprognostic (2.82e-3)" "unprognostic (1.24e-1)" 190.2 82.2 863.3 121.7 900.6 16.6 142.7 908.1 949.4 110.1 612.5 146.5 31.7 124.5 83.4 119.2 104.2 88.2 241.9 884.6 939.2 112.0 41.2 147.9 75.5 1028.2 1010.2 80.4 39.6 85.4 80.0 102.3 981.5 112.2 58.5 461.4 80.8 119.4 61.1 105.6 64.8 194.6 933.0 103.2 75.8 80.5 915.2 40.7 83.5 84.5 96.9 133.4 110.2 1106.4 139.2 46.8 190.5 82.5 344.5 191.5 63.6 593.2 503.3 471.6 328.5 103.7 72.3 63.4 210.9 729.4 226.6 146.4 71.5 181.7 365.3 34.4 40.2 52.4 32.5 26.7 423.9 17.8 62.0 161.8 100.7 260.2 328.5 259.6 360.7 45.7 55.1 111.8 640.6 68.3 21.0 41.1 127.0 160.9 134.3 34.4 200.6 43.8 173.0 71.0 38.0 100.0 310.4 207.6 179.9 409.4 128.1 122.6 487.7 311.3 246.4 234.4 254.5 88.1 59.5 118.7 287.1 33.2 450.8 1.3 39.3 5.2 8.4 78.2 6.5 18.9 6.2 6.9 56.7 13.5 3.8 4.2 1.8 7.9 38.7 25.0 7.9 14.9 863.3 900.6 908.1 949.4 884.6 939.2 1028.2 1010.2 981.5 933.0 915.2 1106.4 137.8 16.0 29.9 40.5 38.6 80.2 124.2 21.8 33.6 172.1 76.9 60.2 246.3 11.5 24.7 5.5 73.0 21.8 13.7 12.7 29.4 74.7 65.4 36.4 33.7 125.1 12.0 7.4 24.8 46.3 61.1 81.5 17.9 85.9 31.1 17.2 89.3 6.5 63.3 92.5 19.1 12.0 8.2 42.6 234.6 55.4 66.8 68.9 74.7 14.0 267.6 315.8 8.2 12.1 48.3 102.5 4.7 109.9 14.8 119.4 5.4 18.3 13.8 129.2 46.0 69.4 78.3 16.5 4.1 42.7 73.3 45.3 19.4 18.5 12.8 178.8 PEAK1 "KIAA2002, sgk269" ENSG00000173517 "Pseudopodium enriched atypical kinase 1" Q9H792 15 77100656-77420144 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 147.4;Excitatory neurons: 162.1;Oligodendrocyte precursor cells: 513.2;Oligodendrocytes: 338.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "NK-cell: 1.8" "Lineage enriched" "Detected in single" 4 "NK-cells: 1.8" "Cell line enhanced" "Detected in all" "TIME: 52.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026313, HPA026517" Approved NA NA "Cluster 15: NK-cells - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 68: Oligodendrocytes - Mixed function" "HPA026313: AB_1856801, HPA026517: AB_1856802" "unprognostic (1.15e-1)" "unprognostic (2.89e-1)" "unprognostic (1.05e-1)" "unprognostic (4.20e-1)" "unprognostic (6.26e-2)" "unprognostic (8.82e-2)" "unprognostic (6.63e-3)" "unprognostic (1.90e-1)" "unprognostic (2.42e-2)" "unprognostic (6.00e-3)" "unprognostic (1.06e-1)" "unprognostic (9.75e-2)" "unprognostic (2.25e-3)" "unprognostic (5.73e-2)" "unprognostic (2.09e-2)" "unprognostic (3.33e-1)" "unprognostic (5.65e-3)" 13.8 4.4 8.9 5.8 13.3 9.1 9.5 5.5 8.8 11.3 1.0 7.8 5.9 7.4 6.4 5.2 5.7 10.0 16.2 8.2 8.4 5.0 3.8 18.0 6.8 6.4 7.8 7.5 4.8 5.4 2.9 16.7 5.8 6.0 8.1 13.7 5.5 7.3 6.7 6.7 7.3 9.9 4.9 29.4 4.9 9.9 11.8 4.7 6.3 8.5 4.7 9.0 7.5 11.7 5.4 7.8 18.1 4.3 33.4 35.7 6.3 28.6 19.7 14.9 14.9 6.3 4.7 4.1 5.0 41.4 5.7 2.6 14.6 4.5 16.9 4.2 7.6 7.7 12.2 3.8 12.2 4.6 3.9 27.6 4.3 28.8 4.8 16.3 42.3 6.6 10.0 4.0 16.1 2.2 2.6 4.9 8.4 3.7 2.1 5.3 10.8 3.0 4.4 9.6 4.0 4.9 11.2 2.3 18.6 19.7 1.7 3.2 52.1 31.5 15.2 13.2 12.2 6.3 9.5 5.9 5.5 10.5 17.3 0.1 0.2 0.4 0.2 0.0 0.4 0.3 0.0 0.0 0.1 0.2 0.1 0.1 0.1 1.8 0.1 0.2 0.0 0.2 8.9 13.3 5.5 8.8 8.2 8.4 6.4 7.8 5.8 4.9 11.8 11.7 48.3 147.4 46.8 101.9 12.6 21.9 7.5 5.6 2.2 18.4 6.1 5.8 46.9 10.0 29.2 1.8 12.5 3.1 12.3 23.9 0.0 6.9 15.1 22.9 19.5 41.2 3.0 10.8 162.1 5.4 2.0 35.6 15.8 10.1 17.7 6.3 31.8 6.0 18.9 20.2 84.4 11.9 2.0 21.3 34.7 13.6 19.9 20.2 12.4 124.6 8.5 28.1 10.3 513.2 338.1 9.8 10.7 16.1 7.0 8.3 15.7 3.7 41.6 20.1 13.1 23.0 37.7 13.6 13.7 5.8 18.0 6.3 8.2 22.6 12.3 7.2 PEG10 "HB-1, KIAA1051, Mar2, Mart2, MEF3L, RGAG3, RTL2, SIRH1" ENSG00000242265 "Paternally expressed 10" Q86TG7 7 94656325-94669695 "Predicted intracellular proteins" "Apoptosis, Differentiation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 172.1;brain: 348.9;placenta: 467.0" "Group enriched" "Detected in many" 11 "Cytotrophoblasts: 2015.8;Syncytiotrophoblasts: 2856.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 773.3;HAP1: 1015.3;Hep G2: 805.0;SCLC-21H: 488.6" "Region enhanced" "Detected in all" "hypothalamus: 110.7" "Low region specificity" "Detected in all" "HPA021324, HPA029915, HPA051038" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol Nucleoplasm "HPA021324: AB_1855181, HPA029915: AB_2673250, HPA051038: AB_2630372" "unprognostic (1.03e-1)" "unprognostic (2.98e-2)" "unprognostic (1.38e-1)" "prognostic unfavorable (8.15e-4)" "unprognostic (1.06e-1)" "unprognostic (5.70e-3)" "unprognostic (9.70e-3)" "unprognostic (2.61e-3)" "unprognostic (5.43e-2)" "unprognostic (1.68e-2)" "unprognostic (1.99e-2)" "unprognostic (3.23e-1)" "unprognostic (1.37e-2)" "unprognostic (1.66e-2)" "unprognostic (5.48e-2)" "unprognostic (6.01e-2)" "unprognostic (2.40e-2)" 3.2 172.1 101.2 2.6 111.9 0.9 24.6 43.7 46.4 7.5 0.0 5.5 0.8 5.6 1.9 2.3 10.0 3.2 1.6 43.5 331.8 7.3 2.4 15.4 5.1 55.2 122.0 65.1 11.4 2.1 88.3 467.0 136.0 2.7 2.0 23.0 9.1 2.6 2.2 0.6 1.5 3.9 32.2 2.0 2.8 41.1 348.9 13.2 11.4 3.3 3.2 3.6 1.6 23.0 22.8 111.6 773.3 329.0 16.0 28.5 45.0 60.7 35.3 42.8 57.3 187.6 37.0 2.5 2.2 70.2 87.5 6.9 1015.3 43.1 58.9 2.9 107.0 0.1 121.8 805.0 12.0 129.6 0.2 63.9 13.9 105.7 73.0 37.1 25.8 0.0 0.5 243.7 84.5 5.8 0.5 0.1 355.4 19.1 70.5 48.5 247.6 67.4 194.3 83.2 488.6 28.2 0.4 16.9 59.9 192.8 105.8 0.3 0.0 33.7 2.0 4.2 46.9 65.2 46.4 97.1 76.3 0.1 14.9 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 101.2 111.9 43.7 46.4 43.5 331.8 55.2 122.0 136.0 32.2 348.9 23.0 4.0 153.8 82.4 11.4 37.1 0.8 9.1 2.5 0.6 87.5 49.4 74.3 42.8 5.7 69.8 16.5 8.4 2015.8 3.3 0.9 64.6 18.1 4.5 9.7 3.0 8.4 60.4 0.0 15.8 5.3 205.1 45.3 2.0 15.4 2.5 24.2 4.2 4.7 175.8 37.0 21.9 0.6 8.2 0.0 0.6 18.9 9.0 1.7 14.2 4.7 0.0 109.0 0.0 10.1 12.8 5.2 0.0 4.1 1.5 9.6 0.0 22.0 8.9 29.7 6.6 173.1 23.0 52.9 51.5 2.5 0.9 2856.1 2.6 68.9 0.7 0.6 PELI2 ENSG00000139946 "Pellino E3 ubiquitin protein ligase family member 2" Q9HAT8 14 56117814-56301524 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 114.3;Microglial cells: 100.2;Oligodendrocyte precursor cells: 150.8;Oligodendrocytes: 77.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 5.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HMC-1: 33.3;JURKAT: 43.8;MOLT-4: 39.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053182 Uncertain Approved "Nucleoplasm,Nucleoli,Intermediate filaments" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 68: Oligodendrocytes - Mixed function" "Nucleoplasm, Nucleoli, Intermediate filaments" "HPA053182: AB_2682072" "unprognostic (3.26e-1)" "unprognostic (2.25e-1)" "unprognostic (9.21e-2)" "unprognostic (8.94e-3)" "unprognostic (1.57e-1)" "unprognostic (1.68e-1)" "unprognostic (2.53e-2)" "unprognostic (3.36e-3)" "unprognostic (1.81e-1)" "unprognostic (2.68e-2)" "unprognostic (1.18e-1)" "unprognostic (2.14e-1)" "prognostic favorable (1.53e-6)" "unprognostic (3.64e-1)" "unprognostic (2.15e-1)" "unprognostic (5.43e-2)" "unprognostic (2.22e-1)" 11.6 3.0 8.1 4.3 7.8 18.6 7.7 27.9 5.9 6.7 5.4 7.0 11.0 6.7 2.5 4.4 6.3 10.0 2.9 5.6 6.6 9.2 2.8 6.7 4.0 8.8 10.9 15.0 28.6 1.9 2.7 3.1 9.3 4.7 3.9 15.1 7.7 3.5 2.4 5.9 9.2 3.3 8.0 6.8 14.4 10.0 10.4 19.1 4.1 3.8 2.0 10.6 5.7 9.2 0.1 3.1 8.8 0.0 4.8 7.2 0.2 1.2 4.2 0.9 0.1 0.2 0.7 0.2 4.2 2.5 0.0 0.9 6.9 0.0 0.4 2.3 2.4 7.9 13.0 0.0 4.1 1.1 33.3 4.5 0.4 0.0 0.0 4.8 1.6 43.8 6.0 0.1 0.9 0.0 39.5 0.4 14.5 0.1 1.2 19.2 0.5 1.8 3.6 15.4 17.5 0.0 0.8 0.1 10.2 5.5 0.0 6.3 0.5 2.6 4.4 0.8 4.4 0.7 0.1 1.0 4.6 5.4 2.6 0.9 1.9 2.4 0.3 1.0 0.5 0.1 0.3 0.2 1.3 0.4 0.2 0.1 5.6 0.3 0.8 0.3 0.0 0.7 8.1 7.8 27.9 5.9 5.6 6.6 8.8 10.9 9.3 8.0 10.4 9.2 13.9 0.0 10.0 114.3 7.7 14.3 10.4 1.7 9.6 30.7 7.1 7.7 2.7 8.6 6.7 12.9 29.2 0.1 11.8 15.0 3.9 5.9 3.7 23.7 14.5 18.0 7.2 5.5 13.5 14.1 0.1 13.5 34.1 21.2 5.7 5.7 17.5 1.0 1.2 21.9 22.1 7.9 2.0 19.7 14.0 5.7 17.1 20.3 17.8 100.2 22.9 9.7 10.3 150.8 77.5 9.1 6.0 18.0 5.6 7.8 12.4 10.1 8.8 19.7 13.1 5.4 22.0 2.0 24.0 4.7 18.3 0.1 6.2 5.6 3.1 12.6 PENK ENSG00000181195 Proenkephalin P01210 8 56436674-56446671 "Plasma proteins, Predicted secreted proteins, Transporters" "Endorphin, Neuropeptide, Opioid peptide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "adrenal gland: 376.2;brain: 164.1;testis: 129.0" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 758.4;Leydig cells: 1137.9;Peritubular cells: 225.7;Spermatocytes: 274.1" "Cancer enhanced" "Detected in many" "lung cancer: 4.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 14.3;ASC TERT1: 8.6;BJ: 7.7;THP-1: 7.7" "Region enriched" "Detected in all" 7 "basal ganglia: 3626.9" "Region enriched" "Detected in all" 7 "basal ganglia: 923.2" "HPA013138, CAB016390" Enhanced "Secreted in other tissues" NA NA 220000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 43: Testis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "CAB016390: AB_2161515, HPA013138: AB_1855191" "unprognostic (6.89e-2)" "unprognostic (1.21e-1)" "unprognostic (2.71e-2)" "unprognostic (1.17e-3)" "unprognostic (1.56e-2)" "unprognostic (3.58e-3)" "unprognostic (1.31e-2)" "unprognostic (3.60e-1)" "unprognostic (6.34e-2)" "unprognostic (5.73e-2)" "unprognostic (3.47e-2)" "unprognostic (4.24e-2)" "unprognostic (1.73e-3)" "unprognostic (1.11e-1)" "unprognostic (4.48e-2)" "unprognostic (3.98e-3)" 8.6 376.2 29.9 4.4 164.1 0.0 4.9 45.2 45.6 9.2 0.5 23.1 1.1 8.1 0.0 1.4 7.6 12.5 25.6 2.7 74.0 0.2 0.2 3.7 0.1 81.4 15.9 29.7 1.1 0.0 17.1 2.9 51.3 22.4 2.0 0.6 2.7 23.4 3.0 0.8 4.2 4.6 54.0 0.1 10.0 129.0 38.0 0.2 1.0 5.3 0.1 0.6 6.2 10.1 0.0 0.0 0.1 0.0 14.3 8.6 0.0 7.7 2.5 1.3 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 29.9 164.1 45.2 45.6 2.7 74.0 81.4 15.9 51.3 54.0 38.0 10.1 0.2 0.0 1.5 0.3 0.5 0.1 0.2 758.4 0.0 0.3 0.1 0.6 0.8 0.0 8.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 85.7 0.1 3.1 0.9 0.0 0.0 0.4 0.0 0.1 16.8 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 15.4 0.0 2.0 0.0 0.7 60.8 1137.9 1.2 0.0 1.9 0.0 0.0 0.0 0.5 0.4 0.0 0.0 225.7 0.0 0.2 0.0 0.0 3.6 0.0 6.6 1.7 1.2 274.1 19.1 0.1 0.4 0.0 0.2 3.1 0.0 0.0 PEX11A "MGC119947, MGC138534, PEX11-ALPHA" ENSG00000166821 "Peroxisomal biogenesis factor 11 alpha" O75192 15 89677764-89690783 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Peroxisome biogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hepatocytes: 38.7;Late spermatids: 39.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SK-BR-3: 54.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (3.67e-1)" "unprognostic (2.58e-1)" "unprognostic (1.18e-1)" "unprognostic (1.08e-1)" "unprognostic (3.73e-2)" "prognostic unfavorable (2.57e-4)" "unprognostic (1.40e-1)" "unprognostic (6.17e-2)" "unprognostic (6.80e-3)" "unprognostic (2.82e-2)" "unprognostic (2.38e-1)" "unprognostic (3.24e-1)" "unprognostic (2.74e-2)" "unprognostic (1.10e-2)" "unprognostic (5.44e-2)" "unprognostic (4.82e-2)" "unprognostic (1.32e-2)" 25.6 10.4 7.9 3.4 8.3 0.8 20.0 6.9 8.5 7.2 12.8 14.5 16.3 6.0 10.5 6.5 9.6 5.4 8.1 7.9 8.7 11.7 39.1 6.1 2.5 7.1 7.8 13.1 11.8 10.0 5.5 3.6 7.2 18.3 12.0 12.7 11.3 10.1 17.9 5.4 12.2 5.5 7.2 4.1 11.3 11.4 9.0 2.3 10.9 12.0 3.7 9.2 6.1 7.9 10.2 6.1 4.6 0.3 23.4 8.4 3.7 5.0 8.5 7.4 12.0 4.3 11.9 4.7 5.5 5.8 10.6 13.3 0.0 7.6 8.5 7.5 16.8 7.1 7.2 6.0 16.8 4.7 2.4 10.4 9.2 4.3 7.1 5.8 5.2 4.6 0.1 1.8 5.6 10.2 0.0 0.6 2.6 20.6 11.1 0.0 0.0 4.2 6.1 6.8 3.4 8.7 16.0 54.4 15.5 8.3 14.4 4.4 4.7 4.9 4.8 13.2 4.0 5.3 9.5 0.2 11.9 0.7 4.3 1.2 0.7 2.3 3.6 1.0 2.0 1.6 1.8 2.0 1.8 0.9 2.2 2.5 0.8 3.1 0.7 0.4 1.7 1.5 7.9 8.3 6.9 8.5 7.9 8.7 7.1 7.8 7.2 7.2 9.0 7.9 1.5 6.4 8.4 12.4 2.0 1.8 9.3 5.2 7.4 8.6 15.3 10.9 8.7 10.0 11.4 5.5 2.1 10.8 1.3 22.1 5.9 7.6 24.8 7.1 5.5 3.1 3.6 0.8 3.0 4.6 7.1 4.6 3.1 5.2 1.3 6.2 4.6 38.7 4.0 18.5 3.5 8.9 6.1 3.5 0.8 39.0 5.3 1.6 3.6 2.8 1.9 14.5 1.0 3.5 3.5 5.5 11.6 2.6 0.6 11.5 20.7 12.6 16.2 9.7 0.0 6.4 4.6 22.6 8.7 5.0 2.0 2.7 1.5 11.0 11.8 11.9 PEX14 ENSG00000142655 "Peroxisomal biogenesis factor 14" O75381 1 10472288-10630758 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Protein transport, Translocation, Transport" "Peroxisome biogenesis disorder, Zellweger syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Rod photoreceptor cells: 67.3;Syncytiotrophoblasts: 64.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046104, HPA049231" Supported Supported "Nucleoli fibrillar center,Peroxisomes" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 46: Photoreceptor cells - Phototransduction" Peroxisomes "Nucleoli fibrillar center" "HPA046104: AB_2679539, HPA049231: AB_2680683" "unprognostic (7.23e-3)" "unprognostic (7.93e-2)" "unprognostic (3.50e-2)" "unprognostic (1.48e-2)" "unprognostic (3.66e-1)" "unprognostic (1.61e-1)" "unprognostic (1.43e-1)" "unprognostic (1.77e-1)" "unprognostic (5.32e-2)" "unprognostic (2.32e-1)" "unprognostic (5.85e-2)" "unprognostic (1.31e-1)" "unprognostic (3.05e-3)" "unprognostic (9.67e-3)" "unprognostic (1.37e-1)" "unprognostic (1.43e-1)" "unprognostic (3.75e-2)" 15.9 13.9 15.5 9.5 15.3 7.8 16.2 11.7 21.8 15.5 10.7 16.8 15.1 17.1 6.4 20.9 13.7 9.3 19.6 15.8 13.6 15.8 33.0 14.3 10.5 14.1 13.1 14.9 11.2 11.8 14.1 11.8 13.8 26.4 8.2 28.1 16.8 23.8 22.6 18.6 16.2 8.5 12.2 12.6 13.8 14.0 14.3 9.7 14.0 11.3 8.6 48.8 17.6 16.0 22.5 21.1 17.2 19.2 12.3 11.6 11.2 25.2 20.8 27.4 26.1 22.4 40.1 16.4 24.9 19.4 16.3 26.3 17.9 24.6 12.9 23.1 30.3 20.4 22.6 31.2 18.8 23.0 27.3 14.2 19.2 20.7 19.0 16.3 17.9 21.2 32.2 16.3 12.4 18.7 21.9 30.4 17.7 17.2 24.6 23.5 14.5 23.3 21.7 14.8 20.5 23.5 24.4 20.2 23.9 13.2 18.4 16.2 17.7 19.9 21.5 19.6 22.0 23.3 20.4 32.3 21.8 31.2 21.7 1.4 2.2 4.6 4.5 1.6 2.8 2.2 2.3 3.4 2.7 2.0 2.9 2.8 0.3 2.6 1.5 2.8 3.0 2.4 15.5 15.3 11.7 21.8 15.8 13.6 14.1 13.1 13.8 12.2 14.3 16.0 5.9 9.6 2.0 32.0 9.2 7.1 13.9 29.2 4.0 15.1 8.3 6.9 8.4 4.3 12.3 9.2 27.1 49.7 11.3 14.1 7.9 17.2 5.9 10.6 4.9 7.8 9.0 4.6 42.0 14.7 18.7 8.1 4.1 7.4 6.3 7.8 8.2 51.1 22.7 18.5 48.4 9.7 14.2 9.0 3.1 3.1 8.1 8.0 12.4 28.1 19.9 21.2 10.3 29.7 29.9 18.2 12.3 5.7 14.7 10.8 29.7 18.5 23.5 67.3 6.6 4.5 11.0 7.1 12.8 7.1 8.1 64.7 9.8 8.3 12.0 13.5 PFDN4 "C-1, C1, PFD4" ENSG00000101132 "Prefoldin subunit 4" Q9NQP4 20 54208087-54228052 "Plasma proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024055 Approved NA NA 220000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA024055: AB_1855236" "unprognostic (2.38e-2)" "unprognostic (1.49e-1)" "unprognostic (3.11e-1)" "unprognostic (5.18e-3)" "unprognostic (2.95e-2)" "prognostic unfavorable (9.40e-4)" "prognostic unfavorable (7.66e-5)" "unprognostic (7.87e-3)" "unprognostic (3.38e-1)" "unprognostic (2.33e-2)" "unprognostic (7.44e-3)" "unprognostic (8.58e-2)" "prognostic unfavorable (1.47e-10)" "unprognostic (9.43e-2)" "unprognostic (2.87e-1)" "unprognostic (1.20e-1)" "unprognostic (7.57e-2)" 5.5 6.2 12.6 4.8 12.9 5.3 6.0 12.5 19.0 5.8 10.7 3.7 2.0 8.0 5.8 5.3 4.7 5.8 14.2 13.1 14.4 6.4 4.0 3.9 6.8 13.3 13.9 7.9 3.7 5.8 2.6 6.6 13.8 5.4 4.2 3.4 4.1 5.2 8.8 4.4 2.7 6.3 12.7 3.2 2.3 7.6 13.2 4.8 6.9 8.2 4.9 5.8 2.7 13.1 9.9 3.4 11.6 3.8 8.1 19.4 11.5 9.2 7.1 21.8 9.6 12.6 9.9 7.2 30.1 10.4 12.6 8.4 13.3 11.9 36.7 7.2 10.0 6.1 13.1 42.6 10.5 12.5 6.8 10.3 16.8 9.4 17.3 11.3 13.8 8.9 11.6 8.2 20.0 38.8 12.8 29.5 14.1 6.2 16.5 9.9 4.1 13.2 18.7 12.7 13.6 14.4 11.2 30.3 31.9 10.5 9.4 25.4 6.9 15.5 18.8 21.8 20.8 5.1 8.1 11.0 15.4 11.0 13.7 3.6 5.4 2.6 4.4 5.8 6.2 6.0 5.9 5.3 7.8 5.2 6.1 5.7 0.8 7.6 5.5 8.6 12.5 5.0 12.6 12.9 12.5 19.0 13.1 14.4 13.3 13.9 13.8 12.7 13.2 13.1 46.7 28.9 32.9 6.2 47.3 91.1 86.4 190.5 59.7 16.5 67.6 82.2 73.6 52.9 68.7 40.5 0.0 124.4 53.2 45.5 107.6 147.5 196.9 67.6 53.5 65.3 71.2 77.2 14.7 137.9 147.1 66.6 19.9 82.1 43.1 52.1 84.6 71.6 95.3 13.5 14.6 56.7 85.5 104.3 104.8 35.7 78.9 46.8 62.2 8.4 172.5 41.7 52.5 12.1 11.9 145.8 68.5 68.1 35.1 69.0 42.7 135.4 66.6 15.7 105.2 55.5 64.6 181.4 92.8 57.3 88.5 93.4 53.6 48.5 66.5 76.7 PGBD5 "DKFZp761A0620, FLJ11413" ENSG00000177614 "PiggyBac transposable element derived 5" Q8N414 1 230314490-230426332 "Disease related genes, Predicted intracellular proteins" Transposition "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 41.8;pancreas: 20.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 26.6;Excitatory neurons: 83.3;Inhibitory neurons: 78.4;Oligodendrocytes: 48.0" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "amygdala: 17.7;basal ganglia: 18.5;cerebral cortex: 35.9;hippocampal formation: 41.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Daudi: 30.7;GAMG: 15.0;NTERA-2: 30.3;RH-30: 16.4;SCLC-21H: 41.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065010 Supported Nucleoplasm NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "HPA065010: AB_2685402" "unprognostic (2.00e-2)" "unprognostic (4.25e-1)" "unprognostic (1.57e-1)" "unprognostic (1.61e-2)" "prognostic unfavorable (8.78e-5)" "unprognostic (1.44e-2)" "unprognostic (4.66e-2)" "unprognostic (4.91e-2)" "unprognostic (3.97e-1)" "unprognostic (1.15e-1)" "unprognostic (7.48e-3)" "unprognostic (2.57e-1)" "unprognostic (3.29e-2)" "unprognostic (6.69e-2)" "unprognostic (2.12e-1)" "unprognostic (3.13e-3)" "unprognostic (2.51e-1)" 0.4 9.4 17.7 0.4 18.5 0.1 0.4 1.1 35.9 18.1 0.0 1.0 0.5 4.6 0.0 1.2 4.9 1.7 13.1 41.8 0.0 1.0 3.1 1.3 0.5 0.9 0.0 0.3 20.3 1.3 5.8 2.1 1.4 0.8 0.7 6.9 5.2 0.7 2.6 0.7 0.5 2.4 0.0 2.2 1.1 5.2 0.1 3.0 5.2 5.1 4.6 0.9 2.6 6.6 0.0 0.0 7.6 0.1 0.1 0.0 0.6 0.5 0.0 0.2 0.0 6.8 0.0 30.7 2.8 0.1 15.0 5.7 2.4 0.0 0.0 0.1 2.6 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.3 0.0 0.0 0.0 0.0 1.5 0.3 0.0 0.2 1.5 0.3 6.2 30.3 0.0 0.2 0.0 16.4 4.9 3.5 0.0 41.4 7.7 1.0 0.1 0.4 0.6 0.4 10.5 0.0 0.0 2.5 0.0 2.5 12.7 10.3 0.0 0.1 2.6 0.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 17.7 18.5 1.1 35.9 41.8 0.0 0.9 0.0 1.4 0.0 0.1 6.6 0.3 0.0 1.9 18.9 0.3 0.1 0.7 0.1 0.0 26.6 1.3 0.6 9.0 4.3 0.4 0.0 20.9 0.1 0.3 0.4 0.0 10.3 0.9 1.4 3.0 0.3 9.1 0.0 83.3 5.8 0.2 0.8 0.0 2.9 10.8 1.9 0.4 4.1 11.5 21.9 78.4 0.4 0.0 3.8 0.3 0.9 0.0 0.9 1.8 4.7 0.1 2.8 0.0 16.1 48.0 5.5 0.3 0.0 0.0 2.1 0.0 0.8 0.9 10.8 0.0 6.4 0.8 0.7 1.8 0.0 0.0 0.3 0.5 2.8 0.6 1.9 PGP ENSG00000184207 "Phosphoglycolate phosphatase" A6NDG6 16 2211593-2214840 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 52.2" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 404.5;Early spermatids: 480.5;Late spermatids: 1591.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043096, HPA046739" Approved Approved "Nuclear bodies" NA NA 250000 "Cluster 52: Eosinophils - Transcription" "Cluster 43: Testis - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 31: Spermatids - Spermatogenesis" "Nuclear bodies" "HPA043096: AB_2678311, HPA046739: AB_2679779" "unprognostic (8.33e-2)" "unprognostic (4.77e-3)" "unprognostic (2.36e-2)" "unprognostic (7.23e-2)" "unprognostic (2.12e-3)" "unprognostic (1.76e-1)" "unprognostic (5.75e-3)" "unprognostic (5.87e-2)" "unprognostic (7.90e-2)" "unprognostic (4.43e-3)" "unprognostic (6.50e-2)" "unprognostic (9.04e-2)" "prognostic favorable (7.05e-4)" "unprognostic (1.28e-1)" "unprognostic (2.63e-1)" "unprognostic (1.11e-1)" "prognostic favorable (6.42e-4)" 7.5 11.8 17.3 6.1 17.6 8.3 7.6 19.5 26.9 6.4 10.6 11.2 6.0 8.7 4.7 6.9 7.2 3.2 33.0 16.3 13.3 14.0 11.5 10.0 6.4 26.8 15.2 4.7 7.8 5.6 11.9 5.3 27.6 8.3 3.8 7.8 7.3 4.8 41.1 7.8 11.5 3.4 12.6 13.7 10.3 52.2 15.7 5.5 16.1 18.0 3.8 8.6 5.4 17.8 16.2 26.0 18.9 17.5 7.3 6.1 35.4 18.5 8.6 16.5 17.0 40.3 20.0 12.3 17.7 8.5 13.5 26.7 12.7 15.7 7.4 17.0 35.3 12.4 44.3 18.4 4.9 21.8 19.6 6.8 7.0 15.6 5.7 6.3 10.9 20.0 22.4 12.7 9.3 44.1 25.1 35.7 24.1 9.8 23.9 40.9 16.3 27.5 13.9 10.1 24.1 14.8 16.8 29.8 13.1 13.4 22.9 25.3 10.9 17.6 22.5 15.9 18.7 30.1 13.9 17.8 5.8 19.2 13.7 0.0 0.8 2.5 0.7 1.2 0.1 0.2 0.4 0.5 0.5 0.8 0.2 0.4 0.6 0.1 1.2 0.7 0.5 0.2 17.3 17.6 19.5 26.9 16.3 13.3 26.8 15.2 27.6 12.6 15.7 17.8 35.0 6.4 7.8 17.6 20.9 23.3 7.8 2.6 4.0 196.1 31.1 33.8 40.7 17.2 5.7 40.5 404.5 121.1 44.8 63.6 58.7 10.4 480.5 28.5 22.5 24.7 29.8 38.3 38.0 14.0 107.1 20.3 28.5 27.7 10.2 54.1 20.3 39.2 58.0 144.7 30.9 37.3 2.0 33.1 64.8 1591.0 25.7 37.9 35.6 7.5 20.2 63.4 42.2 11.6 21.9 14.4 32.5 28.2 36.9 21.9 34.8 39.4 3.4 220.6 39.5 19.3 94.3 162.9 64.8 12.7 31.8 54.5 30.0 70.8 50.5 15.2 PGRMC1 HPR6.6 ENSG00000101856 "Progesterone receptor membrane component 1" O00264 X 119236245-119244466 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 677.4" "Cell type enhanced" "Detected in all" "Hepatocytes: 520.4;Theca cells: 907.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002877, HPA064724" Enhanced Supported "Nucleoli,Endoplasmic reticulum" NA NA 1200000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 5: NTERA-2 - Transcription" "Cluster 52: Non-specific - Transcription" "Endoplasmic reticulum" Nucleoli "HPA002877: AB_1079602, HPA064724: " "unprognostic (6.97e-2)" "unprognostic (1.99e-1)" "unprognostic (1.72e-1)" "unprognostic (4.35e-1)" "unprognostic (6.51e-2)" "prognostic unfavorable (3.02e-4)" "unprognostic (1.58e-3)" "unprognostic (9.28e-2)" "unprognostic (4.66e-2)" "unprognostic (6.20e-2)" "unprognostic (3.08e-2)" "unprognostic (1.04e-1)" "unprognostic (1.14e-1)" "unprognostic (3.06e-3)" "unprognostic (2.08e-1)" "unprognostic (1.01e-1)" "unprognostic (1.11e-1)" 108.0 171.3 97.9 37.5 102.5 25.1 106.0 83.8 115.5 135.4 96.3 98.2 109.3 154.5 273.3 57.0 149.0 56.9 38.6 102.3 127.0 235.4 677.4 62.1 27.6 97.2 109.3 93.3 40.2 113.9 59.1 44.9 126.1 127.6 87.3 80.5 71.4 200.4 15.7 53.2 131.9 85.2 106.1 41.4 77.1 46.5 112.8 33.4 89.0 27.0 29.3 77.3 65.0 116.9 165.6 102.4 196.3 227.7 414.2 196.9 127.1 243.0 281.0 126.1 155.7 124.5 196.6 47.3 259.5 253.8 147.3 128.3 216.5 102.1 168.8 50.8 248.7 53.7 88.5 141.0 69.0 88.4 27.5 204.7 56.5 153.8 79.2 93.5 82.6 55.7 57.2 28.8 150.3 176.5 66.9 64.7 515.8 179.4 170.3 78.5 123.1 68.5 168.7 123.9 182.9 81.7 178.1 291.7 98.9 188.2 67.4 56.2 64.2 87.6 127.7 312.6 233.6 29.9 59.2 51.0 238.8 138.6 170.6 21.0 20.1 20.4 8.7 19.9 11.8 5.8 12.0 12.9 17.0 5.5 12.0 10.1 9.1 8.8 18.4 12.0 13.4 50.2 97.9 102.5 83.8 115.5 102.3 127.0 97.2 109.3 126.1 106.1 112.8 116.9 109.1 125.0 91.4 16.0 19.0 94.1 131.3 67.4 81.4 199.1 110.8 95.1 17.1 120.1 76.7 73.5 68.8 88.2 25.8 170.5 68.4 93.0 4.2 119.7 264.2 81.9 57.7 37.6 36.5 73.0 138.6 153.1 50.4 122.4 40.5 197.0 66.4 520.4 51.8 65.6 58.5 85.0 81.4 35.0 51.2 9.0 172.1 111.1 103.2 15.0 26.5 109.8 18.6 108.6 91.3 68.9 144.7 181.7 22.6 118.8 375.5 295.1 105.4 92.4 105.2 99.2 111.1 68.2 77.2 69.3 87.7 62.1 32.1 907.9 137.6 127.9 PHKA2 "PHK, PYK" ENSG00000044446 "Phosphorylase kinase regulatory subunit alpha 2" P46019 X 18892298-18984114 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" Calmodulin-binding "Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 42.7;Hepatocytes: 57.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002912 Approved Approved Nucleoplasm NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA002912: AB_10961321" "unprognostic (3.90e-2)" "unprognostic (2.06e-2)" "unprognostic (5.10e-2)" "unprognostic (1.43e-2)" "unprognostic (1.90e-2)" "unprognostic (1.12e-2)" "prognostic unfavorable (1.25e-5)" "unprognostic (2.07e-2)" "unprognostic (3.42e-1)" "unprognostic (1.82e-1)" "prognostic favorable (7.68e-4)" "unprognostic (7.51e-2)" "prognostic unfavorable (1.55e-5)" "unprognostic (2.05e-1)" "unprognostic (1.58e-2)" "unprognostic (7.16e-2)" "prognostic favorable (2.96e-5)" 12.7 9.6 4.6 6.8 6.3 15.0 7.6 6.6 5.5 9.0 6.9 6.8 12.5 10.5 6.5 6.3 9.9 8.1 12.6 5.6 5.4 6.7 34.3 6.4 7.7 6.9 5.6 16.8 15.2 8.1 12.8 10.5 6.7 9.7 6.5 10.6 9.5 7.1 7.8 8.8 10.1 6.2 5.5 9.3 8.6 9.7 6.0 12.6 10.1 14.3 7.4 6.2 8.1 7.3 11.3 10.6 6.1 10.2 8.2 7.5 16.6 4.9 4.1 7.1 7.7 11.3 7.3 13.3 3.6 6.4 11.2 10.3 11.0 12.8 7.6 6.5 11.2 15.9 17.6 13.8 5.8 15.2 19.7 12.6 8.3 8.7 12.5 11.8 7.4 13.8 5.3 8.0 5.0 12.0 16.0 25.2 7.5 5.2 11.2 12.4 12.5 14.9 4.6 5.0 5.2 8.0 14.8 15.3 6.8 20.3 18.9 8.8 13.2 9.6 5.3 10.3 7.6 7.6 6.7 10.1 5.4 8.1 5.2 4.3 3.2 7.2 2.0 3.8 2.1 1.6 1.7 1.5 2.1 1.7 1.9 1.9 5.4 3.0 2.5 1.1 2.3 1.9 4.6 6.3 6.6 5.5 5.6 5.4 6.9 5.6 6.7 5.5 6.0 7.3 6.1 9.6 12.9 27.7 5.7 6.5 5.4 6.0 8.6 11.1 8.0 7.4 20.1 12.8 5.1 9.2 10.4 16.8 3.4 9.6 0.0 7.5 7.2 6.4 11.8 7.3 4.2 14.5 15.2 5.1 17.5 5.3 4.1 7.2 1.3 42.7 20.3 57.4 8.0 5.0 19.9 7.4 4.1 18.9 3.8 5.3 7.5 10.5 5.4 13.1 8.3 17.0 7.2 16.6 16.9 6.3 12.6 7.9 7.4 6.9 12.4 4.8 4.1 13.3 0.0 7.4 5.9 7.9 7.9 8.6 4.7 10.5 7.4 12.1 10.7 3.6 PHYHIP "DYRK1AP3, KIAA0273, PAHX-AP" ENSG00000168490 "Phytanoyl-CoA 2-hydroxylase interacting protein" Q92561 8 22219703-22232101 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 217.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 18.9;Basal squamous epithelial cells: 14.8;Excitatory neurons: 48.5;Inhibitory neurons: 15.4" "Cancer enhanced" "Detected in many" "glioma: 6.3;thyroid cancer: 6.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "RPMI-8226: 9.3;SH-SY5Y: 3.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "amygdala: 101.1;basal ganglia: 300.5;cerebellum: 251.7;cerebral cortex: 256.5;hippocampal formation: 296.8" "HPA068030, HPA069318" Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 25: RPMI-8226 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Mitochondria Nucleoplasm "HPA068030: AB_2685944, HPA069318: AB_2686117" "unprognostic (1.19e-2)" "unprognostic (2.33e-2)" "unprognostic (3.06e-2)" "unprognostic (9.22e-3)" "unprognostic (2.07e-3)" "unprognostic (2.35e-1)" "unprognostic (1.59e-1)" "unprognostic (2.80e-1)" "unprognostic (3.01e-2)" "unprognostic (7.44e-3)" "unprognostic (2.36e-1)" "unprognostic (4.05e-2)" "unprognostic (4.44e-5)" "unprognostic (8.62e-4)" "unprognostic (1.36e-1)" "unprognostic (1.35e-2)" "unprognostic (4.09e-3)" 11.3 33.1 106.0 1.5 183.9 0.0 9.3 98.1 217.1 11.6 0.0 14.1 1.3 14.5 2.8 9.8 25.6 6.7 5.2 210.3 21.9 9.4 0.7 2.5 0.2 63.7 11.5 7.1 1.6 0.2 35.7 2.5 58.1 11.9 0.6 2.2 1.8 5.9 0.9 55.8 5.1 8.1 2.0 11.5 3.7 10.7 30.7 0.2 3.9 0.3 0.2 12.1 15.1 137.4 0.6 1.6 0.3 0.0 0.2 0.5 0.8 0.2 0.9 0.2 0.2 0.1 1.4 0.0 1.5 0.5 1.0 2.6 0.0 0.4 0.0 0.0 0.1 0.0 3.0 1.0 1.1 0.0 0.0 0.6 0.0 0.6 0.0 2.5 1.7 0.1 0.1 0.9 0.0 0.0 0.0 0.0 0.6 0.5 0.2 0.0 0.2 9.3 0.0 0.0 2.9 3.5 2.0 0.0 2.4 0.2 0.0 0.2 0.7 0.0 1.4 1.1 0.5 0.6 0.1 0.0 1.4 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 106.0 183.9 98.1 217.1 210.3 21.9 63.7 11.5 58.1 2.0 30.7 137.4 1.1 0.0 0.0 7.2 0.0 18.9 5.5 5.6 14.8 1.5 0.7 1.3 1.4 1.5 1.9 3.7 0.0 0.1 0.1 0.2 0.0 0.2 0.8 0.4 3.6 1.5 0.0 0.0 48.5 2.1 0.4 5.6 0.5 0.2 0.0 0.0 1.4 1.0 0.2 0.0 15.4 0.7 0.0 0.0 1.4 1.8 3.1 0.1 1.8 5.6 0.0 0.6 0.0 7.5 5.8 0.8 0.0 3.8 0.0 1.3 2.6 3.5 0.3 1.1 0.0 0.2 8.0 0.4 0.4 8.2 10.9 2.2 0.2 0.1 0.1 5.0 PIAS2 "ARIP3, miz, PIASX-ALPHA, PIASX-BETA, ZMIZ4" ENSG00000078043 "Protein inhibitor of activated STAT 2" O75928 18 46803218-46920160 "Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "DNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 67.2" "Cell type enhanced" "Detected in all" "Early spermatids: 521.4;Late spermatids: 519.5;Spermatocytes: 238.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068792 Enhanced Supported Nucleoplasm Yes No "Cluster 26: Non-specific - Mitochondria" "Cluster 78: Testis - Spermatogenesis" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "HPA068792: AB_2686037" "unprognostic (9.59e-3)" "unprognostic (2.14e-1)" "unprognostic (1.63e-1)" "unprognostic (2.75e-2)" "unprognostic (1.25e-1)" "unprognostic (6.39e-2)" "unprognostic (1.05e-3)" "unprognostic (3.67e-2)" "unprognostic (1.05e-1)" "unprognostic (3.71e-3)" "unprognostic (1.77e-3)" "unprognostic (1.02e-1)" "unprognostic (1.23e-1)" "unprognostic (1.58e-1)" "unprognostic (6.92e-2)" "prognostic unfavorable (1.27e-4)" "unprognostic (1.71e-1)" 4.8 5.4 7.3 4.1 8.1 7.4 5.1 16.9 9.8 4.9 6.4 4.9 2.8 5.0 7.5 3.7 4.5 4.6 6.8 8.7 6.2 6.4 5.9 4.3 6.2 4.7 6.9 5.0 4.2 11.8 5.6 3.9 5.4 6.5 7.0 10.9 5.5 4.4 16.1 7.7 4.2 4.7 3.7 6.0 4.5 67.2 7.9 4.6 8.2 10.2 5.2 4.1 4.4 8.0 13.7 5.5 6.1 8.7 6.0 7.5 2.9 7.0 5.6 6.0 5.5 6.5 5.1 13.7 3.7 5.3 6.1 4.5 12.3 7.5 8.5 6.6 4.6 8.5 5.4 7.7 5.9 14.3 5.8 7.7 4.5 5.3 5.6 9.7 5.5 11.9 6.4 3.5 12.0 7.4 8.2 8.3 6.7 2.5 3.5 15.0 13.1 0.1 5.5 10.4 11.7 9.0 6.4 4.1 4.7 6.8 6.1 6.3 6.9 12.8 5.5 4.5 5.3 10.1 5.4 17.7 9.5 15.1 12.8 0.7 1.7 1.2 2.0 1.3 1.3 1.6 1.8 2.4 2.0 3.0 2.5 2.1 1.0 1.9 1.3 2.1 1.9 0.8 7.3 8.1 16.9 9.8 8.7 6.2 4.7 6.9 5.4 3.7 7.9 8.0 26.3 19.2 21.9 60.4 25.0 20.6 19.9 15.2 23.9 57.7 21.8 13.2 30.7 12.8 12.6 25.8 89.6 2.6 32.8 18.1 19.6 13.5 521.4 16.6 25.4 26.0 28.5 16.6 137.9 8.9 2.3 20.6 19.4 15.9 14.5 48.4 34.2 22.3 28.1 32.0 134.9 18.0 16.2 50.3 15.7 519.5 33.5 24.2 12.4 73.1 34.7 21.9 40.2 133.7 94.0 7.9 17.1 35.0 30.3 28.4 11.8 23.1 13.9 36.0 6.6 42.5 18.2 238.7 72.4 24.7 15.3 1.4 19.2 35.6 25.5 18.0 PICK1 "dJ1039K5, MGC15204, PRKCABP" ENSG00000100151 "Protein interacting with PRKCA 1" Q9NRD5 22 38056311-38075701 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 116.1;Late spermatids: 85.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000819, HPA072674" Approved Supported Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 35: Non-specific - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 29: Early spermatids - Spermatogenesis" Cytosol "HPA000819: , HPA072674: AB_2686547" "unprognostic (1.97e-2)" "unprognostic (4.61e-3)" "unprognostic (7.79e-2)" "unprognostic (9.26e-2)" "unprognostic (1.29e-2)" "unprognostic (1.81e-1)" "unprognostic (6.04e-2)" "unprognostic (1.65e-2)" "unprognostic (4.62e-2)" "unprognostic (1.65e-1)" "unprognostic (1.68e-3)" "unprognostic (1.20e-1)" "unprognostic (8.56e-2)" "prognostic favorable (5.26e-5)" "unprognostic (1.36e-1)" "unprognostic (2.74e-1)" "unprognostic (4.61e-3)" 8.8 14.9 12.4 4.8 15.2 5.4 13.5 12.8 20.3 9.9 12.9 11.9 10.1 11.7 13.8 15.9 16.3 8.9 18.2 14.5 13.5 15.1 17.5 10.8 5.4 14.5 13.6 15.4 18.5 29.3 28.8 6.7 16.7 25.6 12.2 5.9 18.6 12.6 26.3 16.9 11.3 11.3 11.6 10.1 16.2 27.4 15.6 5.9 14.6 16.2 8.2 9.3 12.0 23.0 19.5 13.7 7.6 10.0 5.3 4.1 11.3 10.7 12.8 22.5 22.7 14.6 12.0 8.6 11.6 13.0 17.0 20.8 21.0 43.2 19.3 5.3 33.6 3.1 16.8 17.1 19.3 10.1 20.4 13.3 24.9 14.8 21.9 22.8 8.8 11.1 6.4 6.2 4.7 12.4 6.0 0.9 12.1 44.3 14.9 5.1 0.3 7.8 25.8 31.1 31.5 16.0 12.0 28.8 11.1 11.1 16.8 7.3 2.4 6.4 12.0 8.6 6.4 13.9 3.4 2.7 13.8 3.4 9.4 0.0 0.9 0.0 0.5 0.4 0.2 0.3 0.5 1.0 1.6 1.1 1.0 0.5 0.6 0.4 0.5 0.3 0.7 0.6 12.4 15.2 12.8 20.3 14.5 13.5 14.5 13.6 16.7 11.6 15.6 23.0 8.1 9.6 10.6 11.1 8.1 8.0 14.2 15.6 12.0 12.7 18.7 16.1 10.2 11.5 12.1 7.3 8.4 26.1 6.0 25.4 11.7 18.8 116.1 15.4 3.6 7.8 10.3 1.7 26.8 15.7 14.8 6.8 29.6 17.3 8.9 36.3 5.7 9.7 15.1 20.2 19.4 20.1 18.3 31.5 13.3 85.5 11.1 16.3 7.2 6.5 16.0 13.6 8.2 8.5 29.0 21.4 18.5 17.0 5.8 22.1 18.3 16.0 12.8 12.5 13.1 6.0 9.5 17.2 6.7 12.0 9.7 38.4 6.8 15.5 18.5 14.7 PIGB ENSG00000069943 "Phosphatidylinositol glycan anchor biosynthesis class B" Q92521 15 55318960-55355648 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Glycosyltransferase, Transferase" Epilepsy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039929 Uncertain Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 32: U-937 - Innate immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane, Cytosol" "HPA039929: AB_10673539" "unprognostic (1.91e-2)" "unprognostic (7.45e-2)" "unprognostic (3.00e-1)" "unprognostic (2.03e-2)" "unprognostic (2.96e-2)" "unprognostic (4.65e-2)" "unprognostic (2.04e-1)" "unprognostic (3.37e-3)" "unprognostic (7.52e-2)" "unprognostic (3.52e-2)" "unprognostic (2.56e-2)" "unprognostic (4.27e-2)" "unprognostic (2.13e-1)" "unprognostic (1.30e-1)" "unprognostic (2.86e-1)" "unprognostic (5.93e-2)" "unprognostic (4.24e-2)" 6.4 4.8 2.3 5.8 2.6 9.1 9.0 2.8 2.6 5.5 3.1 7.0 7.5 6.4 11.0 5.7 7.8 6.3 2.8 2.5 3.3 10.3 9.4 6.3 8.2 2.8 2.7 4.7 5.7 10.6 3.9 4.8 2.6 7.7 7.8 7.9 4.3 6.8 1.5 6.1 5.8 5.6 2.7 6.1 7.6 6.5 2.7 6.3 13.3 1.8 8.6 7.5 3.7 3.1 10.5 12.2 5.8 4.1 6.6 13.2 7.8 9.0 19.9 10.4 17.8 5.1 10.3 10.9 10.4 12.9 15.6 18.3 3.3 9.5 8.6 10.4 6.4 10.9 13.6 6.7 11.9 30.8 8.7 12.5 11.4 7.9 10.7 13.8 13.6 9.2 12.2 6.9 15.0 9.1 3.4 12.8 3.1 7.9 4.8 4.9 5.6 24.1 18.4 12.4 2.5 6.2 8.1 12.2 17.3 5.4 11.7 22.2 9.5 13.6 4.3 3.7 18.6 8.1 15.9 8.6 12.4 34.5 10.2 13.6 7.7 3.3 6.2 9.7 7.0 6.0 6.1 6.9 7.0 3.9 4.8 5.5 14.5 5.3 11.4 5.4 6.5 5.5 2.3 2.6 2.8 2.6 2.5 3.3 2.8 2.7 2.6 2.7 2.7 3.1 3.5 9.6 9.5 17.6 27.5 4.6 9.5 14.9 4.6 3.3 5.6 4.2 3.4 1.5 14.9 0.0 12.5 12.4 11.2 4.8 1.9 7.4 26.8 4.3 3.2 4.7 6.6 8.2 18.3 10.9 12.0 6.0 6.1 6.4 8.2 4.6 6.8 4.4 8.6 1.7 17.7 4.1 4.1 7.5 6.7 5.1 1.5 8.8 3.6 12.2 8.4 2.7 11.3 17.1 14.6 6.9 4.0 1.5 3.8 3.4 6.4 9.7 7.9 9.4 6.6 4.8 4.2 5.9 3.8 5.7 4.0 6.6 12.5 4.2 4.0 7.4 PIGV FLJ20477 ENSG00000060642 "Phosphatidylinositol glycan anchor biosynthesis class V" Q9NUD9 1 26787054-26800659 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Glycosyltransferase, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 50.8;Late spermatids: 96.0;Spermatocytes: 80.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTCEpi: 43.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054181 Approved "Endoplasmic reticulum,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "Endoplasmic reticulum" "HPA054181: " "unprognostic (2.08e-1)" "unprognostic (6.53e-2)" "unprognostic (1.32e-3)" "unprognostic (1.96e-2)" "unprognostic (2.02e-2)" "unprognostic (5.76e-2)" "unprognostic (2.00e-1)" "unprognostic (1.61e-1)" "unprognostic (1.72e-1)" "unprognostic (1.56e-1)" "unprognostic (8.40e-2)" "unprognostic (4.44e-2)" "prognostic favorable (7.60e-7)" "unprognostic (1.71e-1)" "unprognostic (4.24e-1)" "unprognostic (8.92e-2)" "unprognostic (5.96e-3)" 6.6 13.9 4.6 3.4 5.3 3.0 7.6 5.1 4.8 9.5 4.1 8.1 6.5 8.1 13.8 9.0 10.2 6.2 4.4 4.2 4.7 10.9 24.1 6.2 4.2 6.1 5.2 7.9 10.3 13.9 10.0 6.2 5.5 8.4 8.4 3.7 10.0 8.0 4.4 11.3 7.3 6.7 5.2 6.9 8.9 30.0 5.1 6.7 10.6 4.8 6.4 8.5 8.3 5.4 10.6 4.4 4.1 4.7 7.3 10.8 5.8 6.7 14.0 7.6 7.9 2.3 25.9 6.7 7.3 7.7 8.2 20.3 4.2 8.6 8.6 11.5 2.5 5.6 5.1 5.1 10.3 7.7 10.0 11.8 43.8 9.8 12.2 12.0 5.1 9.4 10.0 12.2 14.0 3.9 3.7 3.0 9.9 20.9 3.0 3.8 6.2 15.0 11.0 1.0 7.6 3.9 9.2 4.3 8.7 9.8 14.1 6.5 8.1 10.8 6.5 6.0 1.8 3.8 2.2 2.9 10.7 10.0 8.2 33.1 14.1 11.0 14.0 13.0 21.1 8.8 9.9 14.4 12.5 8.8 10.2 12.4 14.2 21.5 18.5 4.5 9.7 10.8 4.6 5.3 5.1 4.8 4.2 4.7 6.1 5.2 5.5 5.2 5.1 5.4 5.2 3.2 6.0 7.5 6.0 4.2 11.0 27.5 6.2 3.3 10.0 7.6 1.9 4.3 12.7 7.3 8.4 27.4 10.6 5.0 7.9 7.2 50.8 6.7 4.7 4.6 3.5 13.5 2.8 4.6 14.8 8.8 6.1 6.4 0.0 6.8 6.4 16.6 9.2 8.4 3.2 6.5 12.2 5.2 3.2 96.0 7.2 4.2 7.2 2.8 8.2 11.1 7.2 0.0 5.5 4.9 4.8 9.8 6.5 7.6 12.1 10.2 16.3 2.7 0.0 5.7 4.9 80.8 15.1 7.3 4.1 14.1 8.2 12.1 9.2 8.4 PIH1D2 ENSG00000150773 "PIH1 domain containing 2" Q8WWB5 11 112063218-112074274 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "testis: 66.5" "Cell type enhanced" "Detected in many" "Early spermatids: 425.9;Endometrial ciliated cells: 68.8;Late spermatids: 157.5;Respiratory ciliated cells: 115.3;Spermatocytes: 215.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "T-47d: 8.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039496 Uncertain Nucleoplasm,Cytosol NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm Cytosol "HPA039496: AB_10959385" "unprognostic (8.74e-2)" "unprognostic (6.64e-3)" "unprognostic (1.29e-1)" "unprognostic (3.01e-3)" "unprognostic (4.72e-2)" "unprognostic (1.35e-2)" "unprognostic (3.74e-2)" "unprognostic (1.17e-1)" "unprognostic (2.43e-3)" "unprognostic (5.82e-2)" "unprognostic (9.05e-3)" "unprognostic (1.03e-1)" "unprognostic (2.81e-3)" "unprognostic (1.59e-1)" "unprognostic (6.08e-2)" "unprognostic (3.38e-2)" "unprognostic (1.12e-1)" 0.8 1.0 1.8 0.5 1.8 0.4 1.9 1.6 1.8 1.8 9.6 0.9 0.5 1.7 4.8 1.2 14.8 1.6 1.3 1.9 2.0 3.9 0.7 2.9 0.4 4.0 4.6 1.2 1.1 4.1 3.3 0.7 3.4 0.9 0.8 12.4 1.3 1.4 1.0 1.2 0.4 0.6 3.5 0.3 1.0 66.5 2.1 0.6 5.3 0.4 0.4 0.8 0.8 2.5 1.9 1.1 3.1 1.6 0.7 0.8 2.3 0.7 2.2 1.8 2.3 3.0 6.4 0.9 2.4 1.8 2.5 2.6 0.6 1.8 1.9 0.9 2.1 1.3 1.4 1.6 1.3 1.8 0.3 1.2 2.3 4.7 2.6 1.6 0.9 1.3 2.0 0.6 1.3 0.7 0.7 2.5 1.0 1.0 1.6 1.1 2.0 2.6 5.6 0.9 3.6 1.0 2.9 0.5 1.0 0.7 8.0 0.5 0.1 1.6 1.4 0.8 0.6 0.4 0.3 1.3 1.9 0.1 0.9 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.8 1.8 1.6 1.8 1.9 2.0 4.0 4.6 3.4 3.5 2.1 2.5 1.4 6.4 0.5 10.1 0.0 0.6 1.6 7.8 1.8 2.6 1.9 2.2 3.1 5.7 9.9 3.7 2.1 0.9 0.0 0.5 15.6 3.8 425.9 68.8 2.8 1.3 3.0 0.0 5.1 2.3 0.7 1.5 0.0 2.6 1.3 1.5 1.1 0.2 0.7 1.7 5.8 0.5 10.2 0.3 0.4 157.5 2.8 0.8 3.6 1.9 0.6 5.6 0.0 4.0 3.9 1.6 0.4 1.5 0.0 0.6 0.2 10.4 115.3 16.9 0.0 0.7 3.3 215.5 8.4 0.4 1.0 0.3 0.6 1.6 0.4 0.9 PIK3R2 "p85, P85B" ENSG00000105647 "Phosphoinositide-3-kinase regulatory subunit 2" O00459 19 18153163-18170532 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Protein transport, Stress response, Transport" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 14.4;Undifferentiated cells: 16.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" HPA069291 Approved NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA069291: AB_2686109" "unprognostic (2.50e-1)" "unprognostic (1.90e-3)" "unprognostic (1.68e-2)" "unprognostic (1.87e-1)" "unprognostic (2.00e-2)" "unprognostic (9.65e-3)" "unprognostic (1.69e-3)" "unprognostic (2.36e-3)" "unprognostic (9.24e-2)" "unprognostic (4.28e-2)" "unprognostic (1.17e-1)" "unprognostic (3.36e-1)" "unprognostic (1.69e-2)" "unprognostic (2.02e-1)" "unprognostic (6.35e-3)" "unprognostic (8.63e-2)" "unprognostic (2.00e-2)" 7.2 25.6 26.2 6.9 22.9 9.7 7.6 1.1 41.5 17.6 2.0 13.4 20.5 17.5 12.0 26.0 16.7 12.3 12.8 41.0 6.7 9.5 10.5 9.1 5.2 4.4 7.1 21.5 11.0 20.8 21.5 8.7 4.9 15.5 9.6 7.9 15.0 10.4 12.4 26.3 16.7 9.8 4.7 8.7 15.1 11.5 9.4 11.6 10.5 9.9 6.2 15.3 15.3 16.4 39.1 18.0 25.4 36.8 35.3 36.6 40.5 29.4 38.3 21.6 16.6 18.3 20.4 28.0 48.8 41.9 17.5 28.7 15.6 33.2 11.3 25.0 65.5 10.8 21.3 44.0 29.7 24.6 13.4 45.7 36.4 15.0 21.5 36.8 6.6 11.9 33.6 10.8 30.3 57.0 21.5 17.0 32.9 35.8 48.5 19.6 33.4 23.5 37.7 22.8 63.0 68.0 27.1 28.5 28.9 16.0 19.1 15.8 11.4 40.9 20.8 49.2 27.5 22.9 26.4 10.9 33.9 39.4 26.4 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 26.2 22.9 1.1 41.5 41.0 6.7 4.4 7.1 4.9 4.7 9.4 16.4 1.0 6.4 1.1 7.2 0.8 1.9 1.3 1.0 1.8 6.3 3.6 3.2 1.5 2.8 1.0 3.7 4.2 1.7 0.8 6.9 0.0 6.0 0.3 1.3 1.7 0.8 6.1 7.4 11.7 6.2 2.9 1.7 1.1 0.8 2.5 1.4 1.4 1.3 2.2 10.1 11.2 10.5 0.0 4.7 1.0 0.0 1.8 1.7 0.0 3.7 1.6 5.7 0.0 10.6 9.2 6.4 7.0 1.9 0.9 1.1 14.4 1.1 0.5 4.3 0.0 1.4 1.4 0.5 2.1 1.3 2.3 1.2 0.9 3.2 16.4 0.6 PIK3R5 "p101, P101-PI3K" ENSG00000141506 "Phosphoinositide-3-kinase regulatory subunit 5" Q8WYR1 17 8878911-8965712 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 87.4" "Cell type enhanced" "Detected in some" "dendritic cells: 29.9;Kupffer cells: 35.7;Langerhans cells: 40.5;Macrophages: 36.8;Microglial cells: 79.6;NK-cells: 32.0;Plasma cells: 24.7;T-cells: 25.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HDLM-2: 39.2;HMC-1: 5.7;JURKAT: 13.7;U-937: 11.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA044505, HPA052247, HPA052412" Uncertain Supported "Centriolar satellite,Cytosol" No NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 44: HDLM-2 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "Centriolar satellite" "HPA044505: AB_2678964, HPA052247: AB_2681772, HPA052412: AB_2681823" "unprognostic (2.81e-1)" "unprognostic (1.31e-2)" "unprognostic (3.10e-2)" "unprognostic (2.37e-2)" "unprognostic (3.44e-2)" "unprognostic (9.89e-3)" "unprognostic (1.42e-1)" "unprognostic (5.70e-2)" "unprognostic (1.38e-1)" "unprognostic (7.95e-2)" "unprognostic (1.33e-2)" "unprognostic (2.66e-1)" "unprognostic (7.59e-3)" "unprognostic (6.89e-2)" "unprognostic (1.09e-1)" "unprognostic (1.94e-1)" "unprognostic (1.24e-1)" 6.5 3.6 1.4 19.7 1.3 87.4 2.7 1.3 7.5 2.1 1.6 3.3 3.3 1.4 0.8 2.5 3.0 6.6 1.8 1.3 1.7 1.4 2.9 14.1 13.7 4.0 2.7 0.8 1.3 0.8 0.8 3.1 3.6 1.5 2.6 0.0 2.1 1.0 0.7 1.5 9.5 3.9 2.8 22.4 3.6 2.2 6.8 12.3 1.7 0.9 8.9 6.5 1.4 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.2 0.4 1.5 0.0 0.0 0.0 0.5 5.7 0.0 0.0 0.0 0.0 0.0 0.0 13.7 0.0 0.0 0.0 0.3 1.5 2.5 0.6 0.0 0.0 4.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.2 0.0 9.5 16.1 5.7 18.1 14.3 11.8 4.3 10.1 15.6 11.5 5.7 7.5 12.0 34.4 8.6 19.0 9.0 13.2 16.2 1.4 1.3 1.3 7.5 1.3 1.7 4.0 2.7 3.6 2.8 6.8 5.4 0.2 0.0 6.1 0.7 11.7 1.0 0.0 0.0 0.0 0.0 0.2 0.3 2.1 1.5 0.0 0.0 0.0 0.1 29.9 0.0 0.0 0.1 4.5 0.1 0.1 0.7 0.0 4.0 0.3 0.0 0.3 0.5 1.5 0.1 5.1 0.0 1.4 0.4 18.3 0.0 0.5 0.0 0.0 35.7 40.5 12.2 0.3 36.8 1.8 79.6 19.8 0.0 32.0 1.0 0.3 0.0 0.0 0.0 24.7 0.1 0.0 0.2 0.0 0.0 0.0 0.4 1.4 0.6 0.4 0.1 0.9 0.4 25.7 0.0 0.0 0.0 PISD "dJ858B16.2, PSDC" ENSG00000241878 "Phosphatidylserine decarboxylase" Q9UG56 22 31618491-31662432 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Decarboxylase, Lyase" "Cataract, Deafness, Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 223.5;Syncytiotrophoblasts: 245.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 80.7" "Low region specificity" "Detected in all" "HPA031090, HPA031091" Approved Approved "Golgi apparatus,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 47: Cytotrophoblasts - Unknown function" "Golgi apparatus, Cytosol" "HPA031090: AB_10600114, HPA031091: AB_10600893" "unprognostic (7.96e-2)" "unprognostic (5.41e-3)" "unprognostic (2.60e-1)" "unprognostic (8.31e-2)" "unprognostic (5.61e-2)" "unprognostic (4.55e-3)" "unprognostic (2.44e-3)" "unprognostic (8.13e-3)" "unprognostic (6.37e-3)" "unprognostic (1.23e-1)" "unprognostic (1.11e-3)" "unprognostic (1.70e-2)" "unprognostic (4.18e-3)" "unprognostic (1.91e-2)" "unprognostic (4.85e-2)" "unprognostic (3.92e-2)" "prognostic favorable (5.27e-5)" 34.1 13.7 6.7 12.2 6.3 18.7 16.0 14.3 9.8 7.4 7.5 8.9 8.8 10.1 4.8 7.3 10.8 7.1 7.3 6.1 7.5 18.9 6.3 14.7 8.4 7.0 6.0 7.6 9.2 5.0 12.6 19.9 6.8 9.0 2.0 3.5 7.5 5.3 5.3 7.8 7.8 3.2 3.8 18.0 8.2 20.3 7.2 3.8 11.5 3.2 4.3 7.3 7.1 5.1 21.7 19.7 5.8 5.8 17.3 6.6 13.2 17.4 13.6 11.9 12.9 28.6 6.6 12.9 18.0 8.8 15.8 24.0 7.9 15.5 1.9 14.4 16.9 13.5 12.8 23.7 35.9 28.7 34.2 12.4 8.5 21.2 9.1 4.9 10.6 9.0 40.3 7.6 6.9 80.7 12.5 12.4 5.7 14.2 8.1 17.4 6.5 13.0 7.6 18.9 14.2 8.4 10.1 31.8 11.0 4.7 26.5 15.5 21.0 14.9 17.7 9.6 16.3 8.9 13.3 16.2 14.2 19.0 12.1 24.1 21.7 16.1 10.6 15.8 10.3 11.9 7.7 9.0 18.3 11.9 10.3 8.6 47.0 10.4 8.7 8.9 8.2 13.8 6.7 6.3 14.3 9.8 6.1 7.5 7.0 6.0 6.8 3.8 7.2 5.1 11.1 16.0 15.6 17.3 12.4 25.6 34.7 31.5 38.7 26.0 18.6 12.6 55.5 12.8 31.1 42.3 20.9 223.5 12.9 12.0 11.7 33.2 60.0 36.2 17.9 19.6 20.9 32.4 40.3 16.8 25.9 13.6 17.3 87.3 18.3 13.2 8.9 7.5 36.4 18.5 35.5 12.9 22.4 36.4 12.7 81.9 9.6 19.8 3.6 9.4 27.1 11.8 24.7 16.1 19.9 15.9 8.4 7.2 11.4 52.1 12.3 13.9 10.9 25.8 19.7 4.9 11.1 25.0 17.9 27.7 21.3 245.0 11.8 8.3 14.2 43.5 PITPNM1 "DRES9, NIR2, PITPNM, Rd9, RDGB, RDGB1, RDGBA1" ENSG00000110697 "Phosphatidylinositol transfer protein membrane associated 1" O00562 11 67491768-67506263 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 64.6;Distal enterocytes: 69.9;Endometrial ciliated cells: 63.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HDLM-2: 91.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060227 Approved Supported Vesicles,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol Vesicles "HPA060227: AB_2684226" "unprognostic (1.13e-1)" "unprognostic (1.90e-1)" "unprognostic (1.69e-2)" "unprognostic (1.71e-1)" "unprognostic (2.83e-2)" "unprognostic (8.68e-2)" "unprognostic (8.16e-2)" "unprognostic (4.55e-2)" "unprognostic (1.77e-1)" "unprognostic (2.26e-2)" "unprognostic (4.61e-1)" "unprognostic (3.27e-2)" "unprognostic (2.32e-2)" "unprognostic (1.14e-2)" "unprognostic (1.58e-1)" "unprognostic (4.62e-2)" "unprognostic (5.69e-2)" 10.6 24.5 19.6 24.3 12.6 26.8 6.4 6.1 23.2 10.7 13.9 14.4 18.7 9.3 2.4 19.5 23.1 9.0 22.3 13.3 23.8 37.8 11.0 16.3 27.6 14.2 31.0 4.0 9.8 10.3 26.7 8.0 13.5 10.4 7.5 40.7 8.7 10.3 6.9 5.0 21.1 5.9 2.3 21.6 16.0 8.8 51.5 17.4 15.7 18.4 17.2 16.2 9.3 5.5 12.7 31.2 18.8 13.9 20.3 12.1 30.5 12.2 21.5 14.8 8.4 28.5 22.6 12.5 28.7 17.5 28.4 32.4 14.5 27.0 4.8 91.0 6.0 17.0 55.8 10.8 16.0 19.4 35.3 15.0 17.0 22.4 14.7 27.4 17.9 18.7 13.2 11.0 12.5 19.1 33.2 45.6 19.3 35.9 13.5 23.7 6.0 17.3 24.4 25.1 18.1 11.5 27.3 37.6 29.6 9.0 7.4 16.9 17.7 26.5 20.1 16.9 8.9 16.0 8.3 11.2 37.1 22.7 10.6 0.0 1.4 0.9 1.1 3.3 1.0 0.7 0.8 1.0 1.0 0.5 0.3 0.8 1.4 0.1 2.7 0.4 0.7 1.1 19.6 12.6 6.1 23.2 13.3 23.8 14.2 31.0 13.5 2.3 51.5 5.5 7.5 3.2 5.8 2.0 10.8 8.2 6.3 9.3 13.6 45.7 5.4 5.2 8.4 5.7 9.7 20.2 64.6 4.6 10.6 69.9 3.9 11.3 6.1 63.3 16.5 4.9 11.4 0.4 5.1 9.3 8.9 4.2 34.7 24.6 2.5 7.1 3.3 3.4 8.4 38.7 6.6 16.8 10.2 13.2 14.0 17.0 2.1 15.2 3.6 10.3 13.5 20.7 3.1 0.5 0.5 15.9 32.7 1.2 7.5 9.8 39.0 18.9 37.8 53.7 0.0 6.3 9.8 1.4 5.5 11.2 3.3 15.2 14.9 1.4 24.0 19.4 PITX3 ASMD ENSG00000107859 "Paired like homeodomain 3" O75364 10 102230186-102241512 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cataract, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 5.5;skeletal muscle: 16.5;tongue: 6.0" "Cell type enriched" "Detected in some" 4 "Skeletal myocytes: 22.1" "Not detected" "Not detected" "Region enriched" "Detected in single" 14 "midbrain: 5.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 16 "RH-30: 30.3" "Not detected" "Not detected" "Region enhanced" "Detected in some" "midbrain: 9.1" NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (8.13e-2)" "unprognostic (4.07e-1)" "unprognostic (5.15e-3)" "unprognostic (6.30e-2)" "unprognostic (1.06e-1)" "unprognostic (6.04e-5)" "unprognostic (6.30e-3)" "unprognostic (2.02e-1)" "unprognostic (6.36e-2)" "unprognostic (2.67e-2)" "unprognostic (3.73e-2)" "unprognostic (1.76e-2)" "unprognostic (6.76e-3)" "unprognostic (4.13e-2)" 1.2 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.1 0.1 0.2 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 16.5 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.2 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 30.3 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.1 0.0 5.5 0.0 0.1 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.5 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 5.2 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 22.1 0.3 1.4 1.2 0.0 0.1 0.0 0.0 0.2 0.0 0.0 PKDREJ ENSG00000130943 "Polycystin family receptor for egg jelly" Q9NTG1 22 46255663-46263343 "Predicted membrane proteins" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "testis: 3.4" "Cell type enhanced" "Detected in some" "Collecting duct cells: 1.8;Cone photoreceptor cells: 4.2;Early spermatids: 2.5;Horizontal cells: 1.7;Late spermatids: 2.4;Spermatocytes: 8.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA034587 Enhanced NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA034587: AB_10670570" "unprognostic (9.48e-3)" "unprognostic (1.09e-1)" "unprognostic (3.51e-2)" "unprognostic (1.25e-1)" "unprognostic (6.11e-2)" "unprognostic (5.06e-4)" "unprognostic (1.13e-1)" "unprognostic (2.99e-1)" "unprognostic (8.48e-2)" "unprognostic (2.59e-1)" "unprognostic (6.17e-3)" "unprognostic (3.41e-1)" "unprognostic (3.36e-2)" "unprognostic (1.18e-1)" "unprognostic (1.49e-1)" "unprognostic (1.34e-1)" "unprognostic (1.37e-1)" 0.1 0.1 0.1 0.0 0.4 0.1 0.1 0.2 0.2 0.1 0.0 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.3 0.1 0.2 0.1 0.0 0.0 0.0 0.2 0.2 0.2 0.2 0.0 0.1 0.0 0.2 0.1 0.1 0.2 0.1 0.1 0.1 0.6 0.2 0.0 0.1 0.0 0.1 3.4 0.3 0.0 0.1 0.0 0.0 0.1 0.1 0.5 0.1 0.0 0.1 0.3 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.2 0.2 0.1 0.2 0.2 0.2 0.2 0.1 0.3 0.5 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 1.2 0.0 0.0 1.8 4.2 0.0 0.0 0.2 0.0 0.0 2.5 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 1.7 0.0 0.4 0.0 0.0 0.0 2.4 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 8.4 0.8 0.3 0.6 0.0 0.0 0.0 0.3 0.0 PKIB PRKACN2 ENSG00000135549 "CAMP-dependent protein kinase inhibitor beta" Q9C010 6 122471917-122726373 "Predicted intracellular proteins" "Protein kinase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 70.4;intestine: 90.8;parathyroid gland: 63.7;placenta: 60.4" "Group enriched" "Detected in many" 4 "Cytotrophoblasts: 542.7;Distal enterocytes: 750.2;Extravillous trophoblasts: 420.5;Langerhans cells: 251.9;Late spermatids: 251.1;Paneth cells: 355.4;Proximal enterocytes: 255.0;Syncytiotrophoblasts: 959.8" "Cancer enhanced" "Detected in all" "breast cancer: 16.3" "Region enriched" "Detected in all" 5 "cerebellum: 70.4" "Immune cell enriched" "Detected in some" 11 "myeloid DC: 34.8" "Lineage enriched" "Detected in many" 11 "dendritic cells: 34.8" "Cell line enhanced" "Detected in many" "AF22: 71.8;MCF7: 84.9;OE19: 91.2;PC-3: 112.5;RPTEC TERT1: 187.1;SCLC-21H: 157.7" "Region enhanced" "Detected in all" "cerebellum: 63.0" "Region enhanced" "Detected in all" "cerebellum: 45.0" HPA030156 Approved NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 56: Intestine - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA030156: AB_10602816" "unprognostic (1.59e-2)" "unprognostic (1.82e-1)" "unprognostic (1.99e-2)" "unprognostic (1.57e-3)" "unprognostic (1.39e-1)" "unprognostic (9.45e-2)" "prognostic unfavorable (4.72e-7)" "unprognostic (1.94e-2)" "unprognostic (5.88e-2)" "unprognostic (3.91e-2)" "unprognostic (1.26e-1)" "unprognostic (3.58e-2)" "prognostic favorable (2.47e-7)" "unprognostic (1.82e-1)" "unprognostic (1.37e-1)" "unprognostic (2.57e-1)" "unprognostic (1.48e-1)" 2.2 5.8 4.4 9.0 3.9 0.2 23.3 70.4 5.2 4.9 3.4 90.8 15.5 3.4 3.4 5.2 5.5 5.7 0.5 5.9 6.9 2.8 8.2 4.1 2.2 13.9 7.4 0.8 6.3 63.7 22.1 60.4 14.6 6.2 62.4 56.1 8.5 2.4 0.7 9.1 28.3 3.9 3.9 3.2 34.4 4.2 6.8 3.7 1.1 0.6 4.1 5.4 1.2 5.0 0.1 2.8 71.8 0.3 0.6 0.3 62.4 0.0 0.8 0.3 1.2 0.4 3.0 0.0 0.4 0.0 3.8 0.3 0.0 1.5 0.8 0.4 3.7 1.2 3.9 1.7 0.2 0.0 12.3 0.3 1.2 1.2 15.3 34.0 0.3 0.5 22.3 0.4 0.2 84.9 0.3 0.4 29.6 91.2 112.5 0.6 10.8 0.4 187.1 10.6 157.7 0.2 0.0 17.1 2.0 39.4 12.0 1.8 5.7 0.2 47.3 0.2 6.2 0.2 0.3 0.2 46.7 1.5 0.4 0.0 0.6 0.0 0.0 3.2 0.7 0.0 0.0 0.0 34.8 0.1 0.4 0.1 0.1 1.9 0.3 0.5 0.4 0.7 4.4 3.9 70.4 5.2 5.9 6.9 13.9 7.4 14.6 3.9 6.8 5.0 3.0 3.2 3.9 17.0 4.6 19.8 2.3 2.5 2.8 23.6 94.8 53.3 0.3 2.8 10.2 1.8 4.2 542.7 0.9 750.2 19.6 22.6 106.0 5.3 1.6 3.9 98.0 4.0 5.5 35.8 420.5 6.9 52.0 5.5 38.7 0.3 1.1 3.8 53.1 6.7 15.5 94.9 14.2 75.5 251.9 251.1 1.2 51.2 44.4 9.4 25.5 15.2 0.0 6.0 8.5 50.4 355.4 0.4 1.2 13.8 255.0 26.9 58.3 54.8 6.6 0.3 2.7 3.3 5.8 12.4 17.0 959.8 3.5 0.2 92.9 8.3 PKIG ENSG00000168734 "CAMP-dependent protein kinase inhibitor gamma" Q9Y2B9 20 44531785-44624247 "Predicted intracellular proteins" "Protein kinase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 233.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "memory B-cell: 370.6;naive B-cell: 377.4" "Lineage enriched" "Detected in all" 11 "B-cells: 377.4" "Cell line enhanced" "Detected in many" "BJ hTERT+: 540.5;HSkMC: 211.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042703, HPA063690" Uncertain Approved Nucleoplasm,Cytosol No No "Cluster 37: B-cells - Transcription" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cytosol" "HPA042703: AB_10797018, HPA063690: AB_2685091" "unprognostic (3.15e-2)" "unprognostic (5.65e-2)" "unprognostic (8.07e-2)" "unprognostic (1.44e-3)" "unprognostic (3.16e-1)" "unprognostic (9.49e-2)" "unprognostic (3.96e-2)" "unprognostic (6.46e-3)" "unprognostic (1.16e-1)" "unprognostic (1.38e-1)" "prognostic favorable (4.90e-5)" "unprognostic (6.26e-2)" "unprognostic (9.08e-2)" "unprognostic (1.19e-2)" "unprognostic (1.35e-2)" "unprognostic (4.22e-1)" "unprognostic (3.96e-2)" 90.3 76.6 77.4 59.0 80.0 20.7 74.2 70.9 95.6 105.2 78.0 189.1 30.3 111.4 37.8 76.4 101.7 73.8 289.9 82.7 82.5 104.5 44.5 162.9 49.4 80.9 77.0 57.5 32.3 66.8 69.1 82.3 72.5 102.4 31.5 26.9 45.9 75.3 104.8 31.4 72.2 92.6 73.1 42.7 81.8 68.3 83.4 19.3 68.4 91.1 46.7 169.0 68.9 73.4 27.8 27.9 44.7 28.8 67.0 135.7 6.2 66.0 540.5 73.6 55.4 64.7 12.5 108.3 52.7 58.5 61.2 10.6 9.0 14.4 23.9 54.8 16.3 16.7 4.1 45.7 61.7 2.1 1.1 211.7 28.5 35.8 7.9 36.4 167.5 29.3 13.4 2.6 6.8 35.0 17.2 27.5 23.7 0.2 39.4 2.8 1.2 2.6 40.7 5.5 18.0 58.7 16.9 7.9 45.6 19.3 21.0 13.6 108.5 99.9 44.2 44.8 32.3 13.9 41.9 76.3 49.5 1.9 43.8 2.9 1.8 0.7 1.5 1.7 1.3 370.6 1.9 1.8 9.1 377.4 5.4 8.8 2.2 4.4 1.6 35.8 1.0 17.8 77.4 80.0 70.9 95.6 82.7 82.5 80.9 77.0 72.5 73.1 83.4 73.4 93.3 9.6 6.1 26.8 82.9 25.2 14.4 20.3 10.2 24.6 37.6 45.1 233.6 24.3 15.7 46.0 20.9 15.1 6.2 44.2 127.2 70.6 110.1 104.2 91.5 122.3 44.2 34.9 65.9 30.8 17.8 93.2 5.1 18.5 47.5 27.8 65.0 37.8 8.2 10.1 42.7 15.7 32.6 3.8 20.4 40.1 73.0 14.2 49.8 22.5 8.1 94.1 3.1 25.6 25.4 39.1 46.9 61.3 11.8 11.6 19.3 156.6 78.3 28.7 118.3 19.5 153.0 155.9 27.4 5.3 30.0 36.7 8.5 80.8 29.1 10.2 PKLR ENSG00000143627 "Pyruvate kinase L/R" P30613 1 155289293-155301438 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 19.6;kidney: 25.1;liver: 92.5" "Cell type enhanced" "Detected in some" "Early spermatids: 9.3;Erythroid cells: 22.1;Hepatocytes: 16.3;Late spermatids: 23.0;Proximal enterocytes: 14.8;Proximal tubular cells: 48.9" "Cancer enriched" "Detected in some" 9 "liver cancer: 56.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 10 "K-562: 107.8" "Region enhanced" "Detected in single" "basal ganglia: 1.6" "Not detected" "Not detected" "HPA006653, CAB034376, CAB034378" Enhanced Approved Cytosol No NA 5200000 "Cluster 85: Liver - Metabolism" "Cluster 1: K-562 - Erythropoiesis" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "CAB034376: AB_2163671, CAB034378: AB_2252321, HPA006653: AB_2667632" "unprognostic (9.16e-2)" "unprognostic (1.22e-1)" "unprognostic (2.22e-1)" "unprognostic (5.98e-2)" "unprognostic (2.62e-1)" "unprognostic (7.86e-4)" "unprognostic (1.53e-2)" "unprognostic (1.08e-1)" "unprognostic (8.79e-2)" "unprognostic (1.89e-1)" "unprognostic (4.07e-1)" "unprognostic (4.53e-2)" "unprognostic (1.96e-2)" "unprognostic (1.40e-1)" "unprognostic (1.02e-1)" "unprognostic (1.32e-1)" "unprognostic (6.21e-3)" 0.0 0.0 0.0 0.0 0.1 19.6 0.0 0.7 0.1 0.0 0.0 0.4 11.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 25.1 92.5 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 1.2 7.2 0.0 0.0 0.1 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 11.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 107.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.1 0.0 0.5 0.2 0.2 0.3 0.0 0.4 0.0 0.1 0.0 0.0 0.7 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.4 1.5 0.0 1.8 0.0 0.0 0.0 0.6 0.0 0.0 9.3 0.2 0.3 0.1 0.0 22.1 1.2 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.7 16.3 0.2 0.0 1.2 0.9 0.0 0.0 0.0 23.0 0.0 0.3 0.0 1.0 0.1 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 14.8 48.9 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.0 PKNOX1 PREP1 ENSG00000160199 "PBX/knotted 1 homeobox 1" P55347 21 42974510-43033931 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 106.8;Early spermatids: 121.1;Spermatocytes: 99.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004285, HPA057215, HPA065017" Approved Supported Nucleoplasm NA NA "Cluster 35: T-regs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "CAB004285: AB_2164128, HPA057215: AB_2683372, HPA065017: AB_2685405" "unprognostic (1.68e-2)" "unprognostic (2.64e-1)" "unprognostic (1.59e-1)" "unprognostic (8.39e-2)" "unprognostic (1.90e-2)" "unprognostic (4.81e-2)" "prognostic unfavorable (4.54e-8)" "unprognostic (2.03e-1)" "unprognostic (8.03e-2)" "unprognostic (3.67e-2)" "prognostic favorable (6.71e-4)" "unprognostic (9.45e-2)" "unprognostic (3.94e-2)" "unprognostic (1.85e-1)" "unprognostic (1.21e-2)" "unprognostic (6.16e-2)" "unprognostic (4.31e-3)" 4.8 4.2 6.6 4.0 6.6 2.5 3.9 9.6 6.9 8.1 5.5 6.5 2.8 8.3 5.4 4.1 6.5 4.7 3.5 6.7 6.7 6.7 4.4 4.5 5.0 6.9 6.6 8.6 3.9 3.4 4.6 5.3 6.6 5.0 3.8 4.7 4.2 6.6 7.6 5.4 4.3 6.0 7.5 4.7 4.4 8.2 7.3 5.2 11.5 5.9 4.5 7.0 4.6 7.6 8.8 3.0 3.9 3.8 7.3 11.0 4.8 11.0 7.6 6.5 5.6 5.2 6.6 12.2 8.9 9.7 5.1 4.6 9.1 7.0 8.6 8.4 7.3 7.2 5.7 4.9 7.5 6.6 5.4 8.3 11.3 8.1 6.6 6.8 6.3 4.1 5.8 8.8 15.1 5.2 6.2 7.3 6.1 12.4 6.5 9.8 17.7 6.7 13.0 6.9 12.6 7.5 7.8 5.6 7.6 4.5 4.7 8.4 7.5 10.2 5.0 5.7 7.1 5.1 6.1 6.2 12.9 11.6 5.5 0.3 2.1 1.7 3.9 2.9 4.1 2.8 2.8 3.2 1.9 2.2 3.3 3.0 5.7 2.3 1.9 1.7 3.3 2.4 6.6 6.6 9.6 6.9 6.7 6.7 6.9 6.6 6.6 7.5 7.3 7.6 18.4 6.4 15.7 28.1 12.5 17.5 106.8 13.7 17.1 23.7 12.4 11.7 7.4 12.8 18.2 16.5 4.2 14.9 11.1 12.3 9.8 17.1 121.1 15.1 37.7 16.0 14.9 11.0 30.3 12.6 28.8 22.3 3.6 23.8 6.3 17.3 10.0 8.4 12.6 13.5 27.2 11.8 14.2 8.4 22.5 40.8 18.6 15.3 14.2 16.9 20.8 9.5 11.3 27.6 40.8 14.5 7.0 29.3 8.6 32.2 8.5 7.5 16.3 11.5 32.9 27.3 20.8 99.7 26.4 17.1 13.8 29.0 17.1 24.2 10.8 45.2 PLA2G15 "GXVPLA2, LLPL, LYPLA3" ENSG00000103066 "Phospholipase A2 group XV" Q8NCC3 16 68245304-68261058 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid degradation, Lipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 58.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 116.0;Horizontal cells: 38.7;Kupffer cells: 37.1;Syncytiotrophoblasts: 50.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041702, HPA041727" Enhanced Supported Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 38000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Vesicles" "HPA041702: AB_10794486, HPA041727: AB_10793931" "unprognostic (3.47e-2)" "unprognostic (9.99e-2)" "unprognostic (1.54e-3)" "unprognostic (6.84e-3)" "unprognostic (1.38e-2)" "unprognostic (1.65e-2)" "unprognostic (4.12e-3)" "unprognostic (3.16e-1)" "unprognostic (2.12e-2)" "unprognostic (1.84e-2)" "unprognostic (2.56e-1)" "unprognostic (9.29e-2)" "unprognostic (2.45e-3)" "unprognostic (2.98e-2)" "unprognostic (5.40e-3)" "unprognostic (6.28e-2)" "unprognostic (3.47e-2)" 15.1 11.5 12.9 7.6 12.5 7.0 9.8 12.8 18.1 6.6 9.2 8.0 6.9 6.2 8.7 6.2 7.4 9.3 35.5 13.1 14.2 33.4 17.3 17.5 13.6 13.1 14.1 7.7 7.4 11.4 11.4 27.3 14.6 8.1 5.9 4.4 9.1 5.7 58.3 13.9 6.5 8.8 12.4 20.3 8.4 10.8 15.9 11.7 13.2 22.4 5.1 8.8 6.4 16.1 10.0 10.0 7.9 25.5 36.7 26.8 19.0 24.6 31.6 35.7 30.2 26.1 18.6 17.4 31.2 34.1 28.5 15.2 8.5 10.4 15.9 6.0 16.4 5.0 10.4 19.0 19.6 4.6 25.0 19.0 11.2 35.2 5.5 44.6 22.5 8.9 7.9 9.8 23.0 21.3 7.2 14.5 5.1 9.4 12.1 9.9 11.3 55.3 17.7 8.7 3.0 5.1 31.2 9.6 19.2 6.6 25.2 23.7 18.8 31.5 15.0 41.1 16.5 34.6 33.5 22.1 28.6 13.8 12.0 19.6 24.1 16.0 4.7 27.5 4.8 5.0 5.2 7.0 14.1 5.3 6.5 5.5 1.0 2.3 32.4 12.2 5.1 14.6 12.9 12.5 12.8 18.1 13.1 14.2 13.1 14.1 14.6 12.4 15.9 16.1 4.4 6.4 3.3 3.6 3.0 4.8 2.4 6.8 2.8 12.1 7.0 6.0 22.5 1.5 5.1 9.2 8.4 20.9 4.9 8.1 5.9 10.1 1.9 4.3 4.8 5.9 0.0 1.7 7.0 7.2 7.6 8.2 8.6 9.0 15.2 6.6 9.3 13.7 116.0 38.7 6.7 8.5 2.0 37.1 6.8 6.1 2.1 21.4 12.4 10.3 7.7 4.4 3.1 5.5 3.9 6.3 5.0 1.5 2.6 2.6 3.0 19.5 2.7 6.1 0.0 5.5 6.7 3.4 2.8 4.1 3.4 50.8 3.9 3.1 4.1 2.0 PLA2G1B "PLA2, PLA2A, PPLA2" ENSG00000170890 "Phospholipase A2 group IB" P04054 12 120322115-120327779 "Candidate cardiovascular disease genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Lipid metabolism, Phospholipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 1519 "pancreas: 117705.6" "Cell type enriched" "Detected in many" 17 "Exocrine glandular cells: 20351.4" "Cancer enriched" "Detected in many" 185 "pancreatic cancer: 763.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 2.5;U-2 OS: 1.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA047822, HPA060803" Enhanced "Secreted to digestive system" NA NA 3900000 "Cluster 48: NK-cells - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 1: Pancreatic cells - Digestion" "HPA047822: AB_2680169, HPA060803: AB_2684369" "unprognostic (1.28e-4)" "unprognostic (6.02e-2)" "unprognostic (1.84e-2)" "unprognostic (2.86e-2)" "unprognostic (2.74e-2)" "unprognostic (2.41e-1)" "unprognostic (1.05e-1)" "unprognostic (1.13e-1)" "unprognostic (2.63e-2)" "unprognostic (3.61e-2)" "unprognostic (1.27e-1)" "unprognostic (1.03e-1)" "unprognostic (2.80e-4)" "unprognostic (2.15e-1)" "unprognostic (1.97e-1)" "unprognostic (3.60e-1)" "unprognostic (8.61e-4)" 10.0 6.5 0.2 1.7 0.1 2.9 5.8 0.2 0.6 5.8 0.0 2.3 15.8 2.3 0.0 3.3 1.8 0.9 21.5 0.2 0.2 2.7 7.2 32.1 4.0 0.1 0.1 77.5 117705.6 0.0 4.4 6.0 0.2 4.4 0.3 0.7 21.3 0.0 1.9 3.4 7.7 0.1 0.1 3.0 8.7 4.3 0.1 0.3 1.5 0.0 0.0 1.3 1.9 0.1 0.1 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.4 0.1 0.6 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.4 0.0 1.9 0.2 0.2 0.0 0.5 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.3 0.0 0.0 0.0 0.1 0.2 0.1 0.2 0.6 0.2 0.2 0.1 0.1 0.2 0.1 0.1 0.1 0.0 12.8 91.5 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.8 1.3 0.4 0.0 0.8 0.0 0.0 0.0 0.2 0.2 1.9 24.3 10.6 0.4 0.1 1.1 1.2 0.0 0.1 20351.4 0.0 0.3 0.0 0.0 0.0 8.6 0.0 1.9 0.0 0.0 0.1 1.2 0.0 0.0 0.0 41.0 3.1 1.5 0.0 1.0 43.9 0.0 2.1 0.0 0.0 1142.1 1.7 3.4 0.1 0.2 4.1 7.6 1.0 0.0 0.0 0.0 3.4 0.5 0.2 0.0 0.1 0.0 0.3 12.5 1.2 0.1 PLA2G4E FLJ45651 ENSG00000188089 "Phospholipase A2 group IVE" Q3MJ16 15 41981582-42051190 "Enzymes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skin 1: 17.2" "Group enriched" "Detected in some" 4 "Alveolar cells type 2: 12.9;Basal keratinocytes: 18.1;Suprabasal keratinocytes: 44.9" "Cancer enhanced" "Detected in some" "head and neck cancer: 11.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041105, HPA072562" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 31: Skin - Epidermis development" "Cluster 28: Keratinocytes - Keratinization" "Vesicles, Cytosol" "HPA041105: AB_2677300, HPA072562: " "unprognostic (2.98e-1)" "unprognostic (5.52e-1)" "unprognostic (2.60e-1)" "unprognostic (5.99e-2)" "unprognostic (5.12e-2)" "unprognostic (1.54e-1)" "unprognostic (1.99e-1)" "unprognostic (2.77e-1)" "unprognostic (4.22e-2)" "unprognostic (2.43e-1)" "unprognostic (1.22e-1)" "unprognostic (1.83e-7)" "unprognostic (1.81e-1)" "unprognostic (2.68e-1)" "unprognostic (7.48e-2)" "unprognostic (4.67e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.1 17.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.2 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.9 0.0 0.0 18.1 0.3 1.1 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.1 5.1 0.5 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.7 5.4 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 44.9 0.0 0.1 0.0 0.2 0.7 PLAT ENSG00000104368 "Plasminogen activator, tissue type" P00750 8 42174718-42207709 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Plasminogen activation" "Hydrolase, Protease, Serine protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 246.0;urinary bladder: 181.4" "Group enriched" "Detected in many" 4 "Basal prostatic cells: 763.3;Urothelial cells: 992.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 604.7;HMC-1: 425.2;hTERT-RPE1: 344.9;LHCN-M2: 298.2;U-2197: 441.2;WM-115: 806.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003412, CAB009335" Supported Approved "Actin filaments" "Secreted to blood" NA NA 9900000 110000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 17: WM-115 - Nervous system development" "Cluster 22: Epithelial cell types - Mixed function" "Actin filaments" "CAB009335: AB_2237146, HPA003412: AB_1858205" "prognostic favorable (7.57e-4)" "unprognostic (2.23e-1)" "unprognostic (4.08e-1)" "unprognostic (3.39e-1)" "unprognostic (4.88e-3)" "unprognostic (9.39e-2)" "unprognostic (4.65e-3)" "unprognostic (5.78e-2)" "unprognostic (1.55e-1)" "unprognostic (1.75e-1)" "unprognostic (2.98e-3)" "unprognostic (2.46e-1)" "prognostic unfavorable (4.95e-4)" "unprognostic (8.72e-3)" "unprognostic (1.37e-2)" "unprognostic (2.63e-2)" "unprognostic (6.09e-2)" 58.9 44.0 14.0 35.6 13.7 0.1 35.1 14.6 17.4 21.8 10.3 55.3 29.9 49.6 16.8 33.7 49.8 40.4 19.3 12.5 16.6 91.9 5.3 41.3 2.3 15.4 15.4 21.5 16.0 246.0 13.3 44.4 16.6 54.0 25.0 2.1 15.6 29.1 8.8 6.2 34.6 32.9 16.0 2.0 41.8 11.9 18.8 4.4 30.9 9.8 2.7 181.4 33.1 14.0 4.2 1.4 29.0 9.1 43.1 61.9 0.9 125.8 216.4 54.2 43.4 1.4 604.7 0.0 4.4 17.1 28.4 14.5 0.3 23.9 78.5 64.6 8.4 0.7 1.0 0.6 253.9 0.2 425.2 65.6 0.4 140.3 6.0 344.9 103.9 0.2 4.6 0.8 298.2 0.0 0.6 0.5 42.3 0.3 48.2 0.2 103.5 0.3 12.6 0.4 0.3 7.4 0.2 0.4 158.7 39.7 1.0 0.3 189.3 11.6 43.1 441.2 15.6 0.2 1.1 0.2 9.7 0.2 806.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 14.0 13.7 14.6 17.4 12.5 16.6 15.4 15.4 16.6 16.0 18.8 14.0 63.5 0.0 13.7 0.0 2.9 10.8 763.3 155.9 7.4 4.7 103.9 66.3 7.4 1.5 19.1 0.0 4.2 0.6 0.9 0.1 0.0 9.3 0.9 4.8 104.2 98.2 0.0 0.0 1.6 0.6 1.3 136.5 2.0 5.1 164.0 89.7 36.4 0.8 1.9 1.7 4.0 0.0 4.1 1.0 17.7 1.5 3.7 4.7 23.2 25.3 1.6 2.1 1.0 42.7 0.3 52.0 0.0 2.6 2.8 193.3 0.2 0.3 4.0 3.8 13.1 10.8 48.3 1.1 0.6 13.6 13.5 0.7 6.0 0.5 0.5 992.1 PLCD1 ENSG00000187091 "Phospholipase C delta 1" P51178 3 38007496-38029642 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 89.5;Theca cells: 53.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 25.3;fHDF/TERT166: 26.3;hTCEpi: 31.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009913, HPA020107, HPA021677" Approved Approved Microtubules NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" Microtubules "CAB009913: AB_2163388, HPA020107: AB_1855318, HPA021677: AB_1855319" "unprognostic (1.75e-3)" "unprognostic (1.01e-2)" "unprognostic (4.29e-2)" "unprognostic (1.45e-2)" "unprognostic (3.44e-1)" "unprognostic (9.67e-3)" "unprognostic (1.55e-1)" "unprognostic (7.25e-3)" "unprognostic (3.95e-1)" "unprognostic (1.45e-1)" "unprognostic (2.80e-1)" "unprognostic (2.24e-1)" "prognostic favorable (9.25e-11)" "unprognostic (1.50e-1)" "unprognostic (7.71e-2)" "unprognostic (2.93e-1)" "unprognostic (7.88e-2)" 14.8 12.9 14.3 4.6 16.1 4.3 10.6 15.4 15.6 15.9 9.7 15.7 4.9 11.5 4.2 26.2 9.8 5.6 7.2 12.8 19.0 10.1 5.4 11.3 6.6 20.3 18.5 12.7 6.0 3.9 9.3 3.8 19.6 9.1 10.1 2.8 13.0 8.8 2.9 18.5 8.3 5.6 19.4 7.2 8.3 32.6 16.9 9.1 8.3 4.1 6.6 15.7 19.0 21.9 1.0 2.7 9.4 2.6 25.3 22.2 2.8 2.8 11.1 4.2 6.4 1.0 2.3 0.6 1.4 26.3 2.9 15.0 4.8 3.0 1.3 3.9 1.2 0.5 1.7 4.7 14.7 0.0 1.6 18.0 31.6 12.9 1.7 9.4 8.2 2.2 16.3 1.3 9.6 1.2 2.2 1.1 2.4 5.5 2.7 0.9 1.3 3.6 5.1 5.0 0.1 2.6 0.8 12.4 3.2 3.1 2.7 1.2 4.4 2.5 6.3 6.7 0.1 5.2 2.2 0.6 6.4 0.1 1.3 14.6 2.7 0.2 13.0 3.7 15.2 1.3 16.9 12.8 3.8 0.6 10.1 7.9 9.9 5.9 2.2 2.0 16.6 7.4 14.3 16.1 15.4 15.6 12.8 19.0 20.3 18.5 19.6 19.4 16.9 21.9 5.2 3.2 7.5 22.9 3.6 2.8 12.4 9.6 8.0 0.9 5.4 6.1 4.7 8.6 7.3 9.2 2.1 1.8 4.2 89.5 3.9 11.4 1.7 3.3 11.3 8.1 4.9 3.6 1.9 3.0 5.1 10.2 6.6 3.8 4.5 3.6 20.0 4.1 4.0 3.3 2.3 28.3 10.2 3.8 14.5 3.6 12.8 4.3 1.8 3.7 3.4 13.3 1.0 7.1 2.2 4.1 34.7 14.3 5.9 13.2 10.0 5.8 6.2 1.7 6.6 5.4 7.2 3.1 3.7 12.6 5.8 0.8 7.4 53.4 11.3 14.7 PLCXD3 ENSG00000182836 "Phosphatidylinositol specific phospholipase C X domain containing 3" Q63HM9 5 41306952-41510628 "Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.8;heart muscle: 33.2;ovary: 22.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 138.2;Endometrial stromal cells: 58.7;Enteroendocrine cells: 42.4;Inhibitory neurons: 163.5;Microglial cells: 52.5" "Cancer enhanced" "Detected in some" "pancreatic cancer: 2.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 8.5;PC-3: 7.5;SH-SY5Y: 34.3;TIME: 18.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046849 Uncertain Approved "Golgi apparatus" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 35: Non-specific - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" "HPA046849: AB_2679838" "unprognostic (1.71e-1)" "unprognostic (3.84e-2)" "unprognostic (2.00e-1)" "unprognostic (7.04e-3)" "unprognostic (1.43e-1)" "unprognostic (2.44e-1)" "unprognostic (4.90e-2)" "unprognostic (1.34e-1)" "unprognostic (2.63e-2)" "unprognostic (3.12e-1)" "unprognostic (6.38e-3)" "unprognostic (2.57e-1)" "unprognostic (2.73e-2)" "unprognostic (2.15e-3)" "unprognostic (5.91e-5)" "unprognostic (5.11e-2)" "unprognostic (6.75e-2)" 3.9 12.7 4.5 0.5 4.1 0.0 2.4 17.8 4.2 2.9 1.1 0.9 0.5 1.1 0.9 0.6 3.4 2.4 33.2 3.4 9.5 5.9 1.6 1.8 1.6 8.2 10.4 22.5 3.6 0.3 5.3 0.1 16.0 1.0 0.6 0.7 0.4 1.0 0.5 0.7 1.2 1.2 7.7 0.2 5.0 0.4 12.1 0.5 1.5 0.7 0.2 1.4 4.0 6.3 0.0 3.7 0.0 0.0 0.0 0.0 0.0 1.8 8.5 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 4.4 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.4 34.3 0.0 0.0 0.0 0.0 0.0 0.0 18.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.5 4.1 17.8 4.2 3.4 9.5 8.2 10.4 16.0 7.7 12.1 6.3 8.7 0.0 0.0 7.5 0.1 0.1 0.1 0.0 0.0 0.7 0.1 0.0 138.2 5.7 0.0 0.0 0.0 0.1 0.0 0.1 3.9 0.3 0.9 1.7 58.7 13.6 42.4 5.3 27.8 0.0 2.0 10.3 0.0 1.1 0.0 33.4 33.2 0.4 0.1 1.7 163.5 2.2 0.0 0.6 0.3 4.4 7.8 0.2 0.0 52.5 0.0 0.4 0.0 7.5 1.3 0.9 0.0 0.4 0.0 0.3 0.1 10.4 0.0 0.2 6.6 0.2 2.9 0.2 0.0 0.2 0.0 0.1 0.3 9.7 0.1 0.1 PLD6 ENSG00000179598 "Phospholipase D family member 6" Q8N2A8 17 17200995-17206333 "Metabolic proteins, Predicted membrane proteins" "Differentiation, Lipid degradation, Lipid metabolism, Meiosis, Spermatogenesis" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 32.4;Spermatogonia: 23.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 5.8;NK-cells: 6.3;T-cells: 11.9" "Cell line enhanced" "Detected in many" "HAP1: 41.2;REH: 31.5" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" HPA049345 Approved NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 43: Testis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "HPA049345: AB_2680722" "unprognostic (1.71e-1)" "unprognostic (6.80e-3)" "unprognostic (3.21e-2)" "unprognostic (1.39e-1)" "unprognostic (2.95e-2)" "unprognostic (8.21e-2)" "unprognostic (1.31e-1)" "unprognostic (7.83e-2)" "unprognostic (9.01e-2)" "unprognostic (1.48e-1)" "prognostic favorable (1.05e-4)" "unprognostic (1.32e-1)" "unprognostic (1.04e-1)" "unprognostic (6.08e-2)" "unprognostic (1.56e-1)" "unprognostic (3.51e-1)" "unprognostic (2.24e-1)" 4.6 4.1 11.5 1.4 10.8 2.0 3.8 10.7 11.4 7.6 10.3 9.0 1.7 3.5 5.0 1.6 5.7 2.2 5.2 10.9 12.1 2.9 5.9 2.8 3.0 10.3 14.6 7.9 5.0 5.7 8.1 1.8 14.0 5.6 1.7 3.6 3.2 4.4 5.2 4.5 3.2 2.4 8.7 4.3 4.5 21.2 13.1 1.6 3.3 1.4 2.2 4.3 4.4 11.1 7.1 5.4 0.2 6.0 2.3 0.9 0.3 2.2 3.6 4.0 2.4 6.3 2.0 15.4 3.3 2.2 2.4 1.9 41.2 1.2 3.8 9.7 12.0 14.9 4.2 11.3 10.2 11.2 6.0 2.0 4.4 2.4 9.7 4.5 1.0 7.1 13.5 0.4 4.6 9.0 8.3 15.8 0.1 8.0 7.4 31.5 3.1 11.3 3.7 0.5 23.4 9.7 2.8 3.9 7.2 4.3 3.8 17.8 1.1 0.1 0.3 9.0 4.5 1.9 7.5 0.1 4.8 11.4 8.6 0.4 0.4 0.2 2.9 0.3 9.9 5.8 11.3 6.0 0.1 4.8 11.9 5.5 0.5 6.3 0.2 1.5 9.4 4.1 11.5 10.8 10.7 11.4 10.9 12.1 10.3 14.6 14.0 8.7 13.1 11.1 0.6 3.2 3.3 4.6 3.3 5.5 4.5 1.7 9.6 4.5 2.2 3.9 7.2 1.5 1.9 1.8 0.0 5.5 0.5 0.5 1.9 1.4 7.1 7.5 1.5 0.8 1.2 3.4 6.0 0.7 1.3 2.8 1.5 3.4 1.3 3.3 1.8 2.1 2.7 6.7 9.8 2.0 6.1 0.6 1.7 2.7 4.4 0.8 3.6 2.8 0.7 6.5 0.0 3.0 7.1 1.0 0.1 4.9 10.1 5.9 0.8 1.4 6.0 1.3 0.0 1.4 1.5 32.4 23.7 1.3 1.6 0.8 3.6 5.6 1.5 1.2 PLEK P47 ENSG00000115956 Pleckstrin P08567 2 68365282-68397453 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "bone marrow: 604.8" "Cell type enhanced" "Detected in many" "dendritic cells: 310.7;Hofbauer cells: 220.3;Kupffer cells: 213.9;Langerhans cells: 456.5;Macrophages: 412.7;monocytes: 178.3;NK-cells: 355.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 552.9;HL-60: 126.7;HMC-1: 202.5;NB-4: 187.5;THP-1: 215.6;U-266/84: 147.8;U-698: 147.1;U-937: 342.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031838, HPA057341" Enhanced Approved Nucleoli NA NA 380000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" Nucleoli "HPA031838: AB_10602146, HPA057341: AB_2732609" "unprognostic (2.57e-2)" "unprognostic (5.18e-2)" "unprognostic (1.87e-3)" "unprognostic (4.52e-3)" "unprognostic (3.52e-1)" "unprognostic (3.08e-2)" "unprognostic (4.67e-2)" "unprognostic (3.40e-2)" "unprognostic (4.00e-2)" "unprognostic (1.24e-1)" "unprognostic (1.07e-1)" "unprognostic (1.22e-1)" "prognostic unfavorable (1.95e-4)" "unprognostic (3.57e-1)" "unprognostic (4.42e-2)" "unprognostic (2.03e-1)" "unprognostic (1.56e-1)" 36.4 9.8 4.9 99.4 7.1 604.8 8.2 6.0 10.0 6.9 6.5 13.2 10.4 4.7 3.3 6.0 7.2 21.0 5.4 4.9 5.3 4.0 27.5 35.6 129.9 8.0 6.1 2.6 2.7 2.7 1.9 29.2 8.1 4.2 18.8 0.5 5.7 3.1 1.7 3.4 13.0 22.2 7.3 93.5 11.3 3.2 7.2 33.7 3.8 5.2 118.2 52.3 2.5 12.3 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 93.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 552.9 0.0 0.0 0.0 126.7 202.5 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.3 58.9 0.0 0.0 0.2 187.5 0.0 0.0 0.0 1.5 0.1 27.3 0.0 0.0 0.0 0.1 0.4 0.0 0.4 0.0 0.0 215.6 0.1 0.0 0.4 0.1 0.5 7.9 147.8 147.1 0.2 342.5 0.1 231.9 297.5 429.2 298.5 351.6 157.6 157.7 52.2 218.7 229.6 103.6 14.5 161.8 573.9 249.5 390.8 474.8 5.7 606.9 4.9 7.1 6.0 10.0 4.9 5.3 8.0 6.1 8.1 7.3 7.2 12.3 3.4 19.2 24.6 0.0 77.0 6.5 0.3 0.0 0.0 0.0 1.4 3.7 2.3 1.5 15.5 1.8 0.0 1.2 310.7 0.0 0.0 0.2 1.5 0.2 0.3 6.3 0.0 21.9 0.6 0.6 1.8 10.2 1.5 0.3 62.0 0.0 5.7 1.5 220.3 0.0 0.2 0.0 0.0 213.9 456.5 5.1 0.6 412.7 17.8 20.6 178.3 0.0 355.3 0.0 0.1 0.1 0.1 0.4 48.4 0.0 0.0 0.7 13.1 0.1 13.1 1.1 1.8 0.8 0.9 0.6 6.7 2.6 78.3 0.4 0.0 0.3 PLEK2 ENSG00000100558 "Pleckstrin 2" Q9NYT0 14 67386984-67412167 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 51.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 149.0;Pancreatic endocrine cells: 179.8;Suprabasal keratinocytes: 90.6;Theca cells: 107.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "memory CD4 T-cell: 2.0;naive CD4 T-cell: 3.1" "Lineage enriched" "Detected in single" 7 "T-cells: 3.1" "Cell line enhanced" "Detected in many" "A-431: 91.0;CAPAN-2: 94.4;HBEC3-KT: 177.4;PC-3: 64.1;TIME: 69.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA001208 Enhanced Uncertain Vesicles,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" Vesicles Cytosol "HPA001208: AB_1079631" "unprognostic (4.41e-3)" "unprognostic (3.77e-1)" "unprognostic (1.15e-1)" "unprognostic (6.23e-2)" "unprognostic (6.88e-2)" "unprognostic (3.17e-3)" "unprognostic (1.18e-2)" "prognostic unfavorable (1.58e-4)" "unprognostic (1.97e-1)" "unprognostic (9.21e-3)" "prognostic unfavorable (8.26e-5)" "unprognostic (1.06e-1)" "unprognostic (3.09e-3)" "unprognostic (2.90e-1)" "unprognostic (1.29e-1)" "unprognostic (8.98e-2)" "unprognostic (4.59e-2)" 0.8 51.1 0.3 5.5 0.3 12.7 3.9 0.8 0.6 3.9 0.1 25.1 29.6 1.5 32.4 16.4 1.7 3.9 0.3 0.4 0.2 9.7 29.7 1.6 0.2 0.3 0.2 0.6 7.9 7.0 1.3 1.5 0.3 7.7 28.7 0.1 6.8 4.2 0.3 26.5 32.6 1.3 0.2 0.6 20.6 3.1 0.4 22.9 23.5 0.2 5.5 12.1 7.9 0.4 91.0 13.4 0.0 0.1 0.0 1.0 8.4 17.9 2.7 4.2 5.2 48.8 94.4 0.0 17.3 2.5 0.2 42.4 0.1 177.4 9.6 0.1 0.7 0.0 19.4 0.4 3.8 0.0 0.0 1.9 12.3 4.6 55.4 0.0 14.8 0.0 0.4 0.4 3.0 28.9 0.0 0.2 0.3 57.4 64.1 0.0 0.1 14.0 30.0 2.4 0.7 0.2 17.0 7.9 5.2 0.9 11.6 0.9 69.3 0.0 54.1 0.3 0.4 0.3 0.2 0.3 10.7 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.0 0.3 0.4 0.0 3.1 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.3 0.8 0.6 0.4 0.2 0.3 0.2 0.3 0.2 0.4 0.4 0.1 0.0 1.1 1.0 0.6 149.0 29.0 69.9 37.0 0.0 4.9 6.0 0.5 10.0 11.8 5.5 0.0 1.0 0.0 25.0 3.9 42.1 0.1 2.3 0.2 2.0 8.4 16.0 0.8 46.3 5.5 4.2 37.2 2.2 0.0 24.0 0.0 11.5 6.8 0.0 0.6 68.5 26.4 1.3 57.1 0.3 0.3 7.4 21.4 0.0 5.2 0.0 0.0 0.5 0.3 179.8 23.9 0.0 0.0 15.8 47.9 3.2 4.5 0.0 0.0 0.0 4.6 0.4 2.3 21.2 90.6 1.5 1.3 107.7 54.8 25.5 PLEKHF2 "FLJ13187, PHAFIN2, ZFYVE18" ENSG00000175895 "Pleckstrin homology and FYVE domain containing 2" Q9H8W4 8 95133785-95156685 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 84.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Daudi: 102.6;U-698: 109.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024829 Uncertain NA NA "Cluster 10: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA024829: AB_10603127" "unprognostic (4.08e-2)" "unprognostic (2.98e-2)" "unprognostic (5.72e-2)" "unprognostic (2.06e-1)" "unprognostic (1.18e-3)" "unprognostic (9.67e-2)" "unprognostic (4.83e-2)" "unprognostic (1.19e-1)" "unprognostic (2.67e-1)" "unprognostic (1.44e-1)" "unprognostic (3.16e-2)" "unprognostic (5.94e-2)" "prognostic favorable (1.49e-4)" "unprognostic (2.55e-2)" "unprognostic (1.32e-1)" "unprognostic (3.01e-1)" "unprognostic (4.61e-3)" 12.4 6.1 5.5 21.3 5.5 84.8 21.6 6.1 6.7 9.2 6.9 16.0 12.6 7.4 14.6 15.4 8.9 11.2 8.9 5.2 5.7 22.2 14.7 17.5 53.1 6.3 5.8 7.3 11.8 6.9 3.6 15.1 6.2 9.3 13.9 14.8 11.8 7.4 10.7 19.5 13.7 7.1 6.6 22.6 21.9 12.3 5.4 23.8 9.7 9.3 56.1 12.7 7.5 8.3 27.5 4.5 7.0 4.2 10.0 11.1 37.6 14.9 20.0 12.7 13.6 11.3 29.7 102.6 12.6 10.5 6.6 33.1 10.9 18.1 18.3 19.2 7.4 49.4 10.0 8.8 9.9 9.9 68.7 7.1 25.0 10.0 18.8 14.9 14.1 32.9 32.6 13.0 13.6 16.8 29.0 12.8 4.2 50.1 20.6 11.5 7.1 14.0 10.4 24.2 9.3 5.4 11.3 13.5 27.8 9.7 36.2 16.0 9.0 9.8 6.7 8.6 8.7 17.2 14.9 109.4 7.5 22.8 14.1 107.2 21.6 43.0 9.0 18.6 10.8 69.7 11.2 13.9 24.3 78.6 12.9 12.7 29.8 12.4 16.0 10.1 13.7 19.4 5.5 5.5 6.1 6.7 5.2 5.7 6.3 5.8 6.2 6.6 5.4 8.3 29.3 12.8 14.1 7.2 88.8 61.4 73.4 29.7 56.3 17.0 49.0 22.7 7.0 31.5 26.1 5.5 14.6 51.6 17.8 46.7 29.4 13.6 59.5 47.1 12.0 18.5 33.6 34.5 5.0 22.0 36.1 11.9 31.1 59.5 60.4 14.4 25.0 11.0 29.6 6.7 2.4 14.6 57.0 22.6 54.0 19.8 8.7 34.7 21.4 14.0 31.9 19.1 13.4 10.6 4.7 14.6 39.0 3.8 21.3 42.4 20.7 95.9 26.2 31.7 13.1 10.8 14.5 55.2 16.0 47.2 57.7 50.9 27.4 6.0 17.7 75.4 PLEKHG5 "GEF720, KIAA0720, Syx, Tech" ENSG00000171680 "Pleckstrin homology and RhoGEF domain containing G5" O94827 1 6467122-6520074 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 57.4;skin 1: 102.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 17.4" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 57.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "NB-4: 32.1;TIME: 30.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049570 Uncertain Approved Nucleoplasm NA NA "Cluster 61: Skin - Cornification" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "HPA049570: AB_2680818" "unprognostic (5.59e-2)" "unprognostic (1.33e-1)" "unprognostic (2.47e-1)" "unprognostic (2.81e-1)" "unprognostic (1.50e-3)" "unprognostic (5.10e-2)" "unprognostic (1.02e-1)" "unprognostic (5.46e-2)" "unprognostic (4.40e-2)" "unprognostic (1.02e-2)" "unprognostic (4.85e-1)" "unprognostic (2.70e-2)" "unprognostic (1.28e-3)" "unprognostic (4.85e-1)" "unprognostic (1.20e-1)" "unprognostic (3.13e-1)" "unprognostic (4.85e-2)" 18.7 15.0 4.4 2.9 2.6 0.6 12.0 57.4 16.6 14.0 0.0 7.3 6.4 7.5 1.9 21.6 8.6 7.3 16.4 13.0 0.0 6.5 1.8 6.0 5.0 0.0 0.0 7.5 5.1 4.4 43.3 12.4 1.8 9.9 3.5 3.4 9.3 7.2 6.8 102.5 8.4 3.9 0.0 50.9 4.4 5.4 0.0 2.0 7.2 3.0 3.3 5.9 14.3 0.0 7.1 2.7 11.9 9.4 1.5 4.2 3.1 8.4 7.0 3.2 2.1 6.9 18.8 0.3 22.6 2.8 4.9 22.6 2.2 23.7 1.3 16.5 3.0 0.0 15.1 2.9 1.9 0.0 1.3 5.5 10.2 8.1 12.5 17.4 24.9 1.7 0.0 1.5 0.6 5.0 0.5 32.1 4.9 2.3 23.8 0.1 2.7 2.3 6.3 3.1 10.5 25.2 1.1 8.2 1.5 5.3 8.2 0.5 30.3 8.1 5.0 0.0 6.6 0.1 0.0 2.4 9.2 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 2.6 57.4 16.6 13.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 10.6 0.0 1.5 1.0 0.2 7.4 2.3 4.7 8.0 1.4 1.4 2.2 4.1 1.5 3.6 3.7 2.1 2.6 0.1 4.2 0.0 1.3 8.6 2.5 5.9 9.8 3.5 0.4 17.4 1.3 4.0 1.9 3.1 3.2 0.0 4.0 7.5 0.3 5.3 1.7 9.6 6.4 6.1 0.8 1.3 5.7 1.8 2.4 0.0 7.5 0.0 9.7 0.0 2.0 1.2 5.1 5.6 8.6 0.4 3.8 4.1 0.4 2.7 1.5 13.1 2.1 1.7 2.1 5.1 10.8 14.5 1.9 0.7 2.5 2.8 5.8 PLP1 "GPM6C, PLP, SPG2" ENSG00000123560 "Proteolipid protein 1" P60201 X 103773718-103792619 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted membrane proteins" "Cancer-related genes, Disease variant, Hereditary spastic paraplegia, Leukodystrophy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 7004.9" "Cell type enriched" "Detected in some" 12 "Oligodendrocytes: 4822.5" "Group enriched" "Detected in many" 22 "glioma: 160.5;melanoma: 75.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "SK-MEL-30: 241.0;WM-115: 139.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004128 Enhanced NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA004128: AB_1079635" "unprognostic (5.72e-2)" "unprognostic (1.77e-2)" "unprognostic (2.27e-2)" "unprognostic (4.09e-3)" "unprognostic (1.32e-1)" "unprognostic (3.95e-2)" "unprognostic (2.57e-2)" "unprognostic (1.02e-1)" "unprognostic (5.92e-2)" "unprognostic (2.28e-2)" "unprognostic (1.21e-1)" "unprognostic (1.62e-5)" "unprognostic (4.91e-2)" "unprognostic (1.86e-1)" "unprognostic (3.46e-2)" "unprognostic (1.16e-2)" 7.3 15.7 2252.5 4.2 4296.1 0.1 5.4 4251.8 3472.7 17.8 1056.0 73.9 6.3 6.8 6.7 9.9 7.3 9.6 30.1 2314.1 2859.4 2.9 2.0 1.2 0.4 5976.3 3571.3 5.7 2.5 83.1 6.4 0.0 5342.5 21.1 14.9 7.5 6.7 30.0 2.4 24.4 22.4 22.7 3919.9 0.5 15.4 33.5 3592.5 3.8 3.4 6.8 0.4 12.9 21.8 7004.9 0.2 0.0 20.7 0.1 0.0 0.3 0.0 0.0 0.4 0.0 0.8 1.9 0.0 0.0 0.2 0.7 0.1 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.4 4.0 0.0 0.2 0.0 0.9 0.0 0.1 0.0 2.8 0.0 0.0 0.1 0.0 37.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 241.0 6.3 0.1 0.2 0.0 0.1 0.4 0.1 0.2 0.0 0.3 0.2 4.0 0.0 139.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 2252.5 4296.1 4251.8 3472.7 2314.1 2859.4 5976.3 3571.3 5342.5 3919.9 3592.5 7004.9 0.5 0.0 0.0 23.8 0.1 15.9 0.3 0.0 6.2 1.7 0.2 0.5 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.6 0.0 0.0 9.7 0.0 0.0 13.3 0.0 0.0 0.0 188.3 3.3 0.0 0.1 0.0 11.2 0.0 0.0 0.0 5.8 3.1 7.5 0.8 396.6 17.8 0.0 30.7 0.0 31.2 4822.5 0.0 0.0 3.0 0.0 0.8 0.0 0.0 0.0 1.1 0.0 3.1 2.4 0.6 0.3 0.8 2.6 0.0 0.2 5.6 0.0 0.1 PLPP2 "LPP2, PAP-2c, PPAP2C" ENSG00000141934 "Phospholipid phosphatase 2" O43688 19 281040-291403 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cholangiocytes: 204.5;Ductal cells: 352.1;Proximal enterocytes: 209.8;Rod photoreceptor cells: 234.9;Urothelial cells: 205.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 3.2;MAIT T-cell: 6.6" "Lineage enriched" "Detected in single" 41 "T-cells: 6.6" "Cell line enhanced" "Detected in many" "A549: 144.1;CAPAN-2: 154.6;OE19: 255.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055540, HPA058428" Uncertain Supported "Plasma membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane" "HPA055540: AB_2682839, HPA058428: " "prognostic unfavorable (4.55e-4)" "unprognostic (8.91e-3)" "unprognostic (1.06e-1)" "prognostic favorable (3.21e-8)" "unprognostic (2.95e-1)" "unprognostic (1.36e-1)" "unprognostic (3.83e-3)" "unprognostic (5.48e-2)" "unprognostic (1.59e-1)" "unprognostic (5.67e-2)" "unprognostic (1.18e-3)" "unprognostic (3.85e-1)" "unprognostic (3.53e-3)" "unprognostic (1.06e-2)" "unprognostic (1.71e-1)" "unprognostic (1.30e-3)" "unprognostic (1.36e-3)" 4.8 13.2 37.7 8.5 61.6 0.0 36.9 57.1 50.0 63.4 26.2 40.5 62.7 16.8 8.4 27.2 81.8 52.4 1.7 38.8 43.5 11.5 3.7 8.3 1.4 57.3 53.6 2.7 37.3 19.5 11.8 3.6 56.2 31.7 32.1 29.6 105.7 32.9 0.6 53.2 51.0 6.4 44.8 4.7 50.3 7.6 49.2 5.2 5.7 0.5 6.0 36.5 14.2 83.9 85.5 144.1 2.1 0.1 0.0 0.3 0.2 8.2 0.0 25.3 18.9 41.7 154.6 0.0 88.3 11.9 0.1 45.3 0.0 17.6 11.1 0.8 2.6 0.0 55.9 0.0 28.6 0.0 5.5 5.2 7.6 12.7 16.7 53.4 4.2 0.0 0.7 0.1 0.0 98.5 0.4 0.1 61.5 255.8 0.0 0.0 0.0 2.4 62.1 13.7 17.4 40.9 23.3 38.3 60.3 5.8 50.0 2.5 4.5 55.7 36.5 0.5 61.9 0.8 101.7 70.4 15.5 0.0 46.9 0.0 0.0 0.0 3.2 0.0 6.6 0.0 1.3 1.6 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.3 37.7 61.6 57.1 50.0 38.8 43.5 57.3 53.6 56.2 44.8 49.2 83.9 17.0 6.4 7.5 0.0 1.5 0.0 134.2 0.0 8.0 19.7 137.1 149.9 0.0 204.5 35.3 22.0 10.4 0.5 2.7 77.0 3.9 352.1 0.3 115.2 9.2 15.2 8.5 0.0 0.0 139.5 15.1 3.0 91.3 90.1 1.3 0.0 0.0 0.5 0.9 16.8 0.0 38.8 0.0 1.0 0.0 1.6 0.0 1.9 0.0 0.0 2.6 21.7 0.0 0.0 0.0 128.8 85.2 0.0 1.6 97.4 209.8 1.4 91.1 234.9 0.0 0.8 2.7 0.6 35.1 20.3 0.0 0.8 3.5 0.1 87.2 205.8 PLXNA1 "NOV, PLXN1" ENSG00000114554 "Plexin A1" Q9UIW2 3 126988594-127037392 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 48.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007499, CAB012483" Uncertain Supported Nucleoplasm,Cytosol NA NA 10000000 "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Cytosol "CAB012483: , HPA007499: AB_1079637" "unprognostic (1.87e-1)" "unprognostic (1.11e-1)" "unprognostic (4.38e-2)" "unprognostic (1.19e-2)" "unprognostic (1.66e-2)" "unprognostic (4.17e-2)" "prognostic unfavorable (4.13e-6)" "unprognostic (1.79e-2)" "unprognostic (9.06e-2)" "prognostic unfavorable (1.35e-4)" "unprognostic (3.77e-2)" "unprognostic (7.45e-2)" "prognostic unfavorable (5.64e-5)" "unprognostic (4.50e-3)" "unprognostic (7.62e-3)" "unprognostic (1.37e-3)" "unprognostic (1.73e-1)" 11.2 7.6 13.9 7.0 13.0 1.0 9.6 0.6 16.4 11.6 0.5 9.1 3.4 10.9 2.3 11.3 10.2 4.8 15.8 14.0 7.9 8.6 3.2 14.7 6.3 5.5 5.6 13.8 9.3 24.0 5.5 8.2 5.6 9.3 1.9 1.7 12.9 6.3 10.9 15.1 7.9 5.2 1.3 13.2 7.9 9.0 14.8 6.3 9.6 6.1 4.2 9.8 10.0 5.5 45.3 21.1 22.8 18.1 29.3 32.7 36.3 26.3 22.2 14.8 14.7 70.2 20.6 5.0 38.6 28.4 20.0 68.2 11.7 51.6 6.1 7.2 18.6 0.7 13.4 18.3 19.2 5.4 3.6 32.8 35.4 27.4 21.2 14.9 7.5 14.7 26.3 9.1 16.1 26.3 10.6 9.9 22.0 14.2 18.5 14.0 58.0 14.1 12.9 89.4 20.2 22.1 19.1 17.9 24.7 14.7 28.8 33.9 28.0 23.6 30.0 43.4 28.1 5.5 3.9 9.8 33.9 10.2 25.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 13.9 13.0 0.6 16.4 14.0 7.9 5.5 5.6 5.6 1.3 14.8 5.5 1.9 48.1 4.1 8.8 1.8 15.8 5.6 23.4 6.2 6.7 6.6 7.4 13.0 1.5 18.6 12.9 4.2 21.8 0.8 3.6 0.0 8.9 4.4 5.0 10.0 3.8 9.6 0.4 22.1 6.9 2.5 13.8 7.1 5.6 0.0 20.8 2.2 0.9 13.1 20.2 11.3 4.0 0.0 7.4 12.8 1.0 7.8 7.4 8.8 5.6 1.0 2.5 1.0 13.6 3.6 17.0 2.3 6.4 3.1 21.3 7.4 1.5 11.2 3.3 6.6 6.4 9.9 5.3 9.5 6.7 16.1 7.3 2.2 4.7 5.1 9.5 PLXNB3 "PLEXB3, PLEXR, PLXN6" ENSG00000198753 "Plexin B3" Q9ULL4 X 153764196-153779346 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Neurogenesis Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 210.2;intestine: 57.2" "Group enriched" "Detected in some" 8 "Astrocytes: 43.8;Oligodendrocytes: 72.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "WM-115: 70.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048046 Enhanced NA NA 390000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 70: Brain - Nervous system development" "Cluster 17: WM-115 - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "HPA048046: AB_2680239" "prognostic unfavorable (6.13e-4)" "unprognostic (2.60e-1)" "unprognostic (9.10e-4)" "unprognostic (2.30e-2)" "unprognostic (1.45e-1)" "unprognostic (8.53e-2)" "unprognostic (1.15e-3)" "unprognostic (1.29e-1)" "unprognostic (1.23e-1)" "unprognostic (2.17e-1)" "unprognostic (2.66e-1)" "unprognostic (8.76e-2)" "unprognostic (0.00e+0)" "unprognostic (3.68e-2)" "unprognostic (1.14e-1)" "unprognostic (9.73e-3)" "unprognostic (1.98e-2)" 14.7 28.8 74.4 2.0 122.8 0.7 16.0 86.1 110.8 10.8 28.7 57.2 2.3 23.6 3.9 7.0 11.9 4.9 9.6 77.4 83.0 1.8 1.1 2.8 0.5 105.0 102.2 1.8 6.5 0.2 3.1 0.4 101.5 16.6 2.0 2.4 26.3 8.5 0.8 10.0 9.3 6.5 71.3 0.7 13.6 11.5 123.9 0.1 1.7 0.4 0.3 20.8 13.0 210.2 9.3 1.1 1.1 0.7 1.2 0.7 0.7 8.5 1.7 1.1 3.0 0.0 0.1 0.0 5.4 2.4 1.6 1.0 0.0 7.2 0.9 0.1 0.0 5.8 12.0 6.6 2.3 0.0 0.6 1.8 5.2 5.2 3.2 19.8 3.4 0.2 0.5 3.1 2.3 7.6 0.1 1.4 0.2 6.3 14.0 2.8 0.9 0.1 1.4 4.2 2.4 7.5 0.4 7.8 20.2 0.2 10.4 0.0 15.0 8.6 4.4 6.8 10.9 3.0 0.8 0.2 18.6 0.5 70.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.1 74.4 122.8 86.1 110.8 77.4 83.0 105.0 102.2 101.5 71.3 123.9 210.2 0.0 0.0 0.0 43.8 0.1 0.0 0.0 0.0 1.2 0.0 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.1 0.0 0.0 6.6 72.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 PMVK "HUMPMKI, PMK, PMKA" ENSG00000163344 "Phosphomevalonate kinase" Q15126 1 154924740-154936719 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" "Kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 266.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029900 Approved NA NA 15000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 47: Cytotrophoblasts - Unknown function" "HPA029900: AB_10601390" "unprognostic (2.52e-1)" "unprognostic (3.68e-2)" "unprognostic (1.25e-2)" "unprognostic (1.32e-1)" "unprognostic (2.31e-1)" "unprognostic (1.81e-2)" "unprognostic (8.13e-2)" "unprognostic (5.47e-2)" "unprognostic (8.22e-2)" "prognostic favorable (9.70e-4)" "unprognostic (1.41e-1)" "unprognostic (8.76e-2)" "prognostic favorable (4.96e-4)" "unprognostic (2.07e-1)" "unprognostic (1.67e-1)" "unprognostic (1.78e-1)" "unprognostic (2.10e-1)" 39.9 56.4 99.0 29.8 100.1 15.3 35.0 97.9 108.9 33.4 95.0 39.9 45.9 25.9 17.7 77.7 37.2 17.2 63.1 93.9 96.4 53.8 91.9 30.1 34.6 98.6 97.4 35.8 41.6 58.2 60.3 23.7 96.0 32.4 22.2 19.8 34.0 27.1 79.1 69.2 44.2 27.7 96.4 45.7 40.5 26.6 102.3 27.9 31.5 47.4 36.8 31.9 37.9 99.8 51.8 72.9 46.7 72.5 43.6 30.9 48.5 40.5 29.3 38.9 37.0 30.6 101.0 75.1 75.9 49.3 40.5 49.4 65.3 63.9 17.8 103.3 28.9 34.1 104.1 29.0 40.0 51.4 29.3 36.3 58.7 70.2 49.6 19.5 40.0 65.9 36.8 221.7 41.3 108.3 40.8 51.0 41.0 121.7 95.0 60.3 29.8 171.1 66.1 38.4 37.7 91.1 44.1 75.7 51.9 35.0 146.7 91.1 32.7 35.8 29.2 84.4 62.1 174.0 153.2 131.8 58.9 83.9 46.7 28.0 80.9 91.8 68.2 205.6 110.1 114.8 93.1 70.6 93.6 111.1 59.1 59.1 6.9 59.7 219.4 96.5 134.3 80.0 99.0 100.1 97.9 108.9 93.9 96.4 98.6 97.4 96.0 96.4 102.3 99.8 22.7 57.7 37.5 9.4 42.2 69.8 105.9 95.8 51.8 38.5 67.1 68.3 57.3 78.6 42.2 53.3 8.4 235.7 31.5 65.0 266.1 69.6 9.0 45.0 28.5 29.8 66.4 35.6 5.1 71.3 108.1 45.1 46.9 44.2 22.2 49.8 39.3 146.9 141.0 37.0 7.0 78.9 67.1 67.9 49.5 13.5 42.6 47.8 65.8 3.7 49.5 119.1 41.2 8.0 11.8 61.7 61.7 47.8 58.8 53.7 219.3 246.1 22.1 27.4 32.9 46.0 48.4 51.3 51.3 81.0 90.5 227.7 45.1 162.6 79.9 76.2 PNKD "BRP17, DKFZp564N1362, DYT8, FKSG19, FPD1, KIAA1184, KIPP1184, MGC31943, MR-1, MR-1S, PDC, PKND1, TAHCCP2" ENSG00000127838 "PNKD metallo-beta-lactamase domain containing" Q8N490 2 218270392-218346793 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Disease variant, Dystonia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 508.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010134, HPA017068" Approved Enhanced Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA010134: AB_1079645, HPA017068: AB_1855495" "unprognostic (3.15e-3)" "unprognostic (1.80e-2)" "unprognostic (5.86e-3)" "unprognostic (1.89e-2)" "unprognostic (1.90e-1)" "unprognostic (1.60e-1)" "unprognostic (3.81e-2)" "unprognostic (1.54e-1)" "unprognostic (1.37e-1)" "unprognostic (7.51e-2)" "unprognostic (3.29e-1)" "unprognostic (7.67e-2)" "prognostic unfavorable (5.13e-5)" "unprognostic (7.98e-2)" "unprognostic (2.17e-1)" "unprognostic (9.61e-2)" "unprognostic (1.44e-3)" 50.9 88.9 127.6 33.3 134.7 35.4 49.7 131.2 168.4 62.8 129.3 74.7 40.6 45.6 77.3 40.5 60.6 41.6 98.4 127.8 137.5 106.5 191.5 55.5 40.9 133.9 130.9 47.1 46.1 93.4 49.5 46.9 134.1 87.4 54.7 26.7 60.6 55.3 85.1 44.9 51.1 36.4 128.7 58.7 81.6 45.6 137.8 45.8 90.0 93.6 37.6 64.2 45.4 134.7 53.2 68.3 49.1 77.0 72.2 60.6 90.0 32.7 70.3 76.1 85.0 112.9 51.2 61.7 63.7 55.0 83.5 53.6 95.4 61.4 52.9 128.0 119.4 90.0 119.5 169.4 78.7 58.9 38.6 83.0 59.8 51.9 15.0 51.0 83.2 48.0 67.8 78.3 68.4 152.2 77.6 139.5 49.0 121.3 69.3 75.1 49.5 51.8 88.3 79.2 47.4 39.9 23.6 156.9 94.6 52.0 52.4 56.4 51.5 31.4 53.7 37.5 45.5 32.4 35.7 69.0 79.9 95.8 38.8 142.4 111.4 151.9 97.7 114.3 94.2 223.1 105.7 117.7 106.4 187.2 116.4 111.2 31.3 136.2 109.4 99.0 150.0 132.2 127.6 134.7 131.2 168.4 127.8 137.5 133.9 130.9 134.1 128.7 137.8 134.7 84.5 70.5 91.2 30.0 58.2 55.2 91.5 179.2 82.6 54.5 130.1 162.4 154.5 128.7 127.8 196.8 6.2 172.9 48.2 292.0 508.7 70.6 13.5 125.9 116.5 66.9 121.3 56.3 44.9 49.8 105.3 88.5 99.9 114.1 57.1 97.0 83.2 250.4 136.7 35.3 47.4 186.3 187.2 85.3 59.6 16.5 103.2 66.2 136.9 20.6 79.6 168.8 51.5 19.6 32.8 37.7 143.6 124.1 74.6 93.4 162.7 326.7 148.5 41.6 92.1 60.0 128.6 42.5 50.6 113.9 62.4 77.3 52.5 97.2 228.1 117.5 PNMA3 "MA3, MA5, MGC132756, MGC132758" ENSG00000183837 "PNMA family member 3" Q9UL41 X 153056409-153060467 "Predicted intracellular proteins" "Tumor antigen" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 37.3" "Group enriched" "Detected in some" 4 "Excitatory neurons: 42.1;Inhibitory neurons: 38.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NTERA-2: 3.2;SCLC-21H: 1.0" "Low region specificity" "Detected in all" HPA047920 Approved NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA047920: AB_2680210" "unprognostic (1.66e-2)" "unprognostic (8.97e-3)" "unprognostic (8.70e-2)" "prognostic unfavorable (4.14e-5)" "unprognostic (9.43e-2)" "unprognostic (3.10e-3)" "unprognostic (1.16e-1)" "unprognostic (3.77e-4)" "unprognostic (2.84e-2)" "unprognostic (6.20e-2)" "unprognostic (7.62e-4)" "unprognostic (1.93e-1)" "unprognostic (5.92e-3)" "unprognostic (2.93e-3)" "unprognostic (7.25e-2)" "unprognostic (7.84e-2)" "unprognostic (2.07e-2)" 0.2 1.3 4.3 0.8 5.2 0.3 0.2 1.5 9.4 0.3 0.3 0.4 0.2 0.3 37.3 0.3 1.6 0.2 1.4 5.0 5.4 1.4 0.4 0.4 1.5 5.5 3.6 0.5 0.3 0.6 9.3 0.1 5.4 0.5 0.1 2.1 0.3 0.4 0.1 0.4 2.2 0.1 2.0 2.5 0.4 8.9 5.9 0.5 1.2 0.2 1.3 0.2 0.3 5.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.7 0.0 0.0 0.0 0.2 0.0 0.8 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 5.2 1.5 9.4 5.0 5.4 5.5 3.6 5.4 2.0 5.9 5.5 0.1 0.0 0.0 9.4 0.3 0.3 0.0 0.0 0.0 7.5 0.2 0.4 2.9 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.3 0.1 0.3 0.2 0.0 0.0 42.1 0.0 0.0 0.2 0.0 0.0 0.0 3.5 0.4 0.0 0.1 6.7 38.6 0.0 0.0 0.9 0.3 1.4 1.2 0.4 0.0 3.7 0.1 3.4 1.0 9.5 2.7 0.0 0.0 0.4 0.2 0.2 0.0 3.8 0.0 2.9 0.0 0.0 0.3 0.1 2.1 0.0 0.0 0.0 1.0 0.7 0.0 0.1 PODNL1 "FLJ23447, SLRR5B" ENSG00000132000 "Podocan like 1" Q6PEZ8 19 13931187-13953392 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 13.4;Bipolar cells: 38.7;Leydig cells: 18.3;Peritubular cells: 38.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 6.6;HSkMC: 11.6;hTERT-RPE1: 18.8;SiHa: 9.7;U-2 OS: 6.7" "Not detected" "Not detected" "Region enriched" "Detected in some" 11 "spinal cord: 18.9" HPA042807 Approved "Secreted - unknown location" NA NA "Cluster 71: Testis - DNA repair" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 56: Bipolar cells - Visual perception" "HPA042807: AB_10795514" "unprognostic (1.24e-1)" "unprognostic (4.94e-2)" "unprognostic (8.08e-3)" "unprognostic (2.13e-1)" "prognostic unfavorable (5.61e-8)" "unprognostic (1.78e-1)" "unprognostic (1.86e-2)" "unprognostic (3.68e-1)" "unprognostic (2.02e-1)" "unprognostic (3.08e-3)" "unprognostic (4.37e-2)" "unprognostic (1.01e-1)" "unprognostic (0.00e+0)" "unprognostic (3.94e-3)" "unprognostic (1.79e-1)" "unprognostic (4.99e-2)" "prognostic unfavorable (4.49e-4)" 1.8 0.7 1.9 0.9 1.7 0.5 4.9 2.3 1.8 5.6 0.8 2.8 0.4 1.5 0.2 8.2 2.1 1.3 4.7 1.2 3.6 1.7 0.5 5.1 0.2 4.3 4.4 3.3 1.5 0.1 5.1 3.7 3.0 7.9 0.3 2.0 5.3 0.9 1.6 11.4 2.3 0.5 3.1 1.0 1.7 7.2 3.7 0.0 3.1 1.3 0.2 2.7 12.0 2.0 0.3 0.4 0.4 0.2 0.6 1.5 0.1 4.1 2.4 0.8 1.6 0.3 0.4 0.2 0.3 6.6 0.2 1.6 0.1 0.1 0.4 1.5 0.6 0.8 0.4 0.0 5.1 0.2 0.5 11.6 0.7 1.1 0.1 18.8 0.0 0.1 0.4 0.3 1.6 2.7 0.2 0.2 0.1 0.3 0.4 0.1 0.1 0.0 0.3 0.0 0.7 0.4 9.7 0.1 0.3 0.4 0.1 0.5 0.7 2.0 6.7 0.5 0.2 0.3 0.0 0.1 0.8 0.9 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 1.9 1.7 2.3 1.8 1.2 3.6 4.3 4.4 3.0 3.1 3.7 2.0 1.4 0.0 0.5 2.3 0.0 1.3 0.9 13.4 0.0 38.7 2.1 8.0 1.6 0.0 1.4 0.0 2.1 0.4 0.2 1.8 0.0 0.2 1.7 0.5 6.1 0.9 0.0 2.7 0.5 0.0 0.2 4.7 0.0 0.4 0.0 0.5 0.7 0.1 9.8 1.7 0.7 1.1 0.0 1.2 1.7 2.1 18.3 0.9 1.8 1.9 0.0 1.8 0.0 1.5 0.3 0.6 9.0 38.0 0.0 0.5 0.6 0.1 1.4 4.6 0.0 0.6 1.0 1.0 0.7 2.6 4.3 0.8 0.2 0.1 1.4 1.6 POLG2 "HP55, MTPOLB" ENSG00000256525 "DNA polymerase gamma 2, accessory subunit" Q9UHN1 17 64477785-64497054 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "DNA replication" DNA-binding "Disease variant, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Skeletal myocytes: 92.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "CAB017030, HPA023202, HPA078396" Approved Supported "Nuclear bodies,Mitochondria" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 7: Non-specific - Mitochondria" Mitochondria "Nuclear bodies" "CAB017030: , HPA023202: AB_1855523, HPA078396: " "unprognostic (1.76e-1)" "unprognostic (2.20e-1)" "unprognostic (1.59e-1)" "unprognostic (7.02e-2)" "unprognostic (6.01e-2)" "unprognostic (2.91e-2)" "prognostic unfavorable (1.39e-6)" "unprognostic (4.38e-2)" "unprognostic (8.46e-2)" "unprognostic (3.14e-1)" "unprognostic (5.17e-3)" "prognostic unfavorable (6.59e-4)" "prognostic unfavorable (1.17e-5)" "unprognostic (5.17e-2)" "unprognostic (1.58e-1)" "unprognostic (2.88e-2)" "unprognostic (4.82e-2)" 4.5 5.8 2.7 4.4 3.0 3.6 4.5 3.9 4.5 6.8 3.0 4.7 3.5 4.7 2.0 4.0 5.6 2.4 5.0 2.8 3.6 5.7 5.3 3.9 5.4 3.2 3.0 7.9 4.7 2.4 4.0 2.9 3.1 5.1 1.9 2.6 3.9 2.9 6.8 4.2 5.6 2.0 2.9 7.5 4.0 12.8 3.1 6.3 5.8 4.2 4.0 4.8 5.3 3.9 8.1 10.4 6.7 7.6 7.2 4.7 8.4 4.6 4.6 7.0 5.9 10.1 6.2 15.7 5.4 2.8 6.5 5.3 9.3 3.9 8.8 4.6 11.0 9.9 12.2 10.5 7.0 14.2 10.6 4.5 4.7 5.3 7.2 8.4 4.7 7.6 18.3 4.7 6.5 10.0 15.3 15.4 7.3 8.6 11.2 13.3 23.8 14.2 6.4 2.4 9.3 10.0 4.4 7.1 8.0 8.7 7.4 12.0 6.1 7.0 9.9 5.8 12.3 8.4 7.2 11.3 5.9 13.4 4.8 7.2 5.2 6.0 6.5 3.2 6.6 10.7 7.5 6.2 9.7 11.9 9.7 9.7 0.9 5.8 8.4 4.4 8.1 4.0 2.7 3.0 3.9 4.5 2.8 3.6 3.2 3.0 3.1 2.9 3.1 3.9 24.6 12.8 21.2 7.8 19.6 8.2 13.7 7.8 16.5 5.0 30.1 37.5 18.4 12.8 13.3 3.7 0.0 13.0 22.7 31.7 0.0 5.4 14.7 16.5 26.7 16.0 10.9 20.4 9.1 3.8 14.4 19.2 14.8 29.2 13.3 9.9 14.6 4.7 9.2 6.7 7.4 13.9 6.1 6.9 7.1 7.3 6.5 17.7 7.2 11.2 8.0 4.5 18.6 13.0 14.1 2.9 21.8 3.0 6.3 9.8 8.9 5.2 7.1 9.2 6.6 92.0 18.4 49.7 9.2 10.8 8.7 4.0 16.2 15.2 19.8 5.2 POLK "DINB1, DINP, POLQ" ENSG00000122008 "DNA polymerase kappa" Q9UBT6 5 75511756-75601144 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, DNA synthesis" "DNA-binding, DNA-directed DNA polymerase, Mutator protein, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 236.8;Oligodendrocytes: 159.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012035, HPA057303, HPA068117, HPA069375" Enhanced Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm "HPA012035: AB_2668606, HPA057303: AB_2683406, HPA068117: AB_2685957, HPA069375: AB_2686131" "unprognostic (9.66e-2)" "unprognostic (5.29e-2)" "unprognostic (5.37e-2)" "unprognostic (2.70e-1)" "unprognostic (1.86e-1)" "unprognostic (1.66e-1)" "unprognostic (1.73e-2)" "unprognostic (7.76e-2)" "unprognostic (1.65e-2)" "unprognostic (6.29e-3)" "unprognostic (2.42e-1)" "unprognostic (5.93e-2)" "unprognostic (1.80e-2)" "unprognostic (9.96e-3)" "unprognostic (1.58e-1)" "unprognostic (9.64e-2)" "unprognostic (2.02e-1)" 4.7 4.3 2.3 3.7 5.0 2.7 5.4 7.0 4.5 6.8 1.9 3.2 2.4 6.3 4.6 3.4 4.0 3.7 4.6 3.1 5.4 4.7 4.9 4.9 4.0 5.6 4.2 6.0 4.3 5.5 3.2 6.3 5.7 4.3 3.1 5.2 4.2 3.9 4.6 4.1 3.1 4.1 3.6 5.6 3.7 3.1 4.7 3.9 7.6 3.3 3.6 3.2 3.9 10.5 6.7 6.7 4.1 5.3 5.3 10.5 3.5 12.5 8.8 9.5 9.8 4.3 5.2 6.9 10.0 8.3 6.2 2.5 3.8 4.3 11.4 7.6 4.5 6.3 5.7 2.1 10.1 4.0 4.9 5.0 5.1 7.7 5.3 7.6 8.0 4.4 5.6 3.9 9.1 0.5 7.9 3.2 1.5 0.7 3.9 3.3 10.6 4.8 5.7 2.2 4.1 4.6 9.4 2.5 3.4 2.8 3.7 3.8 10.4 6.9 3.6 3.3 7.2 4.5 4.4 6.0 4.6 6.2 12.2 5.8 5.3 2.7 2.4 6.0 2.0 5.1 2.6 3.0 4.8 4.1 3.2 2.2 4.6 3.9 11.5 5.8 3.4 2.0 2.3 5.0 7.0 4.5 3.1 5.4 5.6 4.2 5.7 3.6 4.7 10.5 45.8 32.1 44.6 65.6 36.3 14.7 21.8 22.1 20.5 32.9 19.5 15.0 21.8 24.3 26.1 29.5 20.9 17.3 37.5 8.3 23.5 20.3 236.8 19.5 32.1 34.4 14.9 29.2 63.5 15.8 13.0 33.7 17.3 21.0 51.9 33.8 57.1 25.0 21.8 65.6 60.0 11.3 24.4 39.2 25.0 58.7 37.6 33.3 23.2 73.1 55.8 19.6 25.7 84.4 159.6 19.1 15.1 38.4 26.4 14.6 17.8 21.2 20.8 38.8 6.6 38.5 27.8 61.3 23.6 14.5 12.9 6.7 27.6 48.8 12.2 11.6 POLR1G "A34.5, ASE-1, CAST, CD3EAP, PAF49, RPA34" ENSG00000117877 "RNA polymerase I subunit G" O15446 19 45406644-45410737 "Predicted intracellular proteins" Transcription "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Cytotrophoblasts: 15.8;Extravillous trophoblasts: 26.3;Hofbauer cells: 11.5;Syncytiotrophoblasts: 7.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 14.5" "Lineage enriched" "Detected in all" 4 "dendritic cells: 14.5" "Cell line enhanced" "Detected in all" "U-251 MG: 200.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041664, HPA041734" Supported Enhanced "Nucleoplasm,Nucleoli fibrillar center,Mitochondria" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Nucleoli fibrillar center" Mitochondria "HPA041664: AB_10795693, HPA041734: AB_10794489" "unprognostic (1.03e-1)" "unprognostic (8.98e-2)" "unprognostic (9.28e-2)" "unprognostic (1.37e-3)" "unprognostic (2.46e-1)" "unprognostic (4.10e-3)" "prognostic unfavorable (4.79e-9)" "unprognostic (1.62e-3)" "unprognostic (3.21e-1)" "unprognostic (5.01e-2)" "unprognostic (2.99e-2)" "unprognostic (7.26e-2)" "unprognostic (6.29e-9)" "unprognostic (1.02e-1)" "unprognostic (2.81e-1)" "unprognostic (1.38e-2)" "unprognostic (4.53e-2)" 3.2 2.4 2.9 3.3 3.0 2.1 3.1 4.1 4.3 2.4 1.1 2.5 2.4 2.7 1.4 4.3 3.0 2.8 3.5 2.9 2.4 2.7 2.6 2.0 3.5 3.4 2.6 3.5 3.8 2.9 1.9 2.2 3.6 2.2 2.1 2.7 2.8 1.9 6.7 4.4 1.9 3.0 1.1 2.1 1.8 1.8 3.4 2.1 2.3 4.5 4.0 4.1 2.4 3.8 31.4 29.0 5.3 20.6 7.5 6.5 20.3 15.3 5.2 26.2 15.1 32.5 21.5 48.3 14.8 11.3 20.6 29.5 46.4 43.0 18.4 22.1 28.7 24.3 11.0 23.9 12.8 25.3 8.9 9.4 27.3 38.2 20.7 7.0 19.2 16.0 63.0 8.9 25.6 37.0 18.7 9.3 37.0 34.6 27.3 25.1 19.5 32.2 10.5 22.7 30.8 9.6 30.9 40.6 6.4 10.6 19.9 15.4 18.2 36.5 36.7 20.4 200.5 16.1 74.0 51.6 16.8 37.6 25.9 1.5 2.7 0.3 1.4 3.5 3.1 2.7 2.0 2.2 4.2 3.0 2.9 3.5 1.3 3.3 2.8 14.5 1.3 2.0 2.9 3.0 4.1 4.3 2.9 2.4 3.4 2.6 3.6 1.1 3.4 3.8 3.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 15.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 26.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 11.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 7.7 0.1 0.0 0.0 0.0 POLR2D RPB4 ENSG00000144231 "RNA polymerase II subunit D" O15514 2 127843553-127858155 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 74.3" "Cell type enhanced" "Detected in all" "Late spermatids: 170.2;Spermatocytes: 86.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034694, HPA046092" Approved Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Nuclear speckles" "HPA034694: AB_2674284, HPA046092: AB_10963049" "unprognostic (3.57e-2)" "unprognostic (3.76e-2)" "unprognostic (2.59e-1)" "unprognostic (2.54e-2)" "unprognostic (2.77e-1)" "unprognostic (1.27e-1)" "prognostic unfavorable (8.91e-4)" "unprognostic (2.51e-1)" "unprognostic (7.95e-3)" "unprognostic (2.64e-3)" "unprognostic (1.97e-1)" "unprognostic (2.51e-1)" "prognostic unfavorable (2.79e-4)" "unprognostic (3.66e-2)" "unprognostic (6.57e-2)" "unprognostic (1.17e-1)" "unprognostic (2.38e-1)" 12.3 10.4 7.2 14.4 9.8 32.4 11.9 9.6 8.3 9.4 7.3 12.0 9.7 10.3 8.0 12.3 10.6 8.4 10.0 7.5 8.7 8.8 19.2 10.2 19.7 8.0 8.9 15.0 14.7 10.4 8.3 15.9 8.3 9.5 14.7 8.1 8.4 9.2 29.3 11.3 9.3 15.0 8.4 12.8 9.4 74.3 8.1 28.3 9.1 27.1 26.9 15.3 8.4 11.0 63.4 40.6 73.9 51.9 26.8 29.2 59.0 59.1 27.9 69.6 61.9 92.0 50.9 97.7 49.6 40.0 39.8 32.7 107.0 51.2 107.3 57.7 58.3 96.6 37.9 85.4 31.4 104.9 51.6 20.8 37.8 93.3 53.2 19.3 46.1 70.4 137.1 84.8 40.4 50.1 105.0 47.5 103.6 65.9 46.4 99.3 77.8 88.0 23.1 42.6 45.7 60.9 39.9 48.9 50.7 54.7 54.6 71.4 47.0 60.1 84.4 34.4 69.0 99.4 173.4 173.0 52.4 51.2 60.5 9.9 22.8 17.3 26.3 31.7 25.0 22.8 21.0 23.2 29.9 20.2 27.6 23.7 7.3 25.8 35.0 19.5 20.6 21.3 7.2 9.8 9.6 8.3 7.5 8.7 8.0 8.9 8.3 8.4 8.1 11.0 10.9 3.2 11.7 2.6 22.0 10.8 22.0 7.6 15.9 15.1 9.8 6.2 10.4 11.5 10.1 12.9 8.4 33.0 23.4 7.6 11.7 20.3 70.8 13.2 16.1 12.5 8.4 31.1 4.7 17.5 31.0 15.2 9.7 10.4 18.4 23.1 11.4 17.0 21.7 33.7 5.2 11.9 8.2 11.1 14.1 170.2 17.7 13.3 8.8 2.8 23.4 13.2 16.5 2.5 7.5 18.4 8.4 18.4 46.6 26.2 10.2 11.1 6.8 13.7 13.1 18.5 15.5 86.1 48.9 19.3 10.1 26.7 17.1 31.5 14.0 18.9 POLR2I "hRPB14.5, RPB9" ENSG00000105258 "RNA polymerase II subunit I" P36954 19 36113709-36115213 "Metabolic proteins, Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 1145.8;Late spermatids: 2796.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035632, HPA045156" Uncertain Enhanced Nucleoplasm NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "HPA035632: AB_2674711, HPA045156: AB_10964748" "unprognostic (1.95e-2)" "unprognostic (7.88e-3)" "unprognostic (3.54e-1)" "unprognostic (7.41e-3)" "unprognostic (2.05e-1)" "unprognostic (3.01e-1)" "unprognostic (1.24e-2)" "unprognostic (4.12e-2)" "unprognostic (7.39e-2)" "unprognostic (4.69e-3)" "unprognostic (2.86e-2)" "unprognostic (8.16e-2)" "unprognostic (1.83e-1)" "unprognostic (3.36e-2)" "unprognostic (3.84e-3)" "unprognostic (1.08e-1)" "unprognostic (1.16e-1)" 32.6 41.0 97.6 23.3 104.3 44.4 34.8 104.2 118.6 30.6 85.8 35.0 28.9 28.4 39.7 40.2 55.7 27.2 78.9 94.6 100.8 32.9 40.2 25.5 31.5 98.5 98.6 50.0 83.9 61.3 26.1 21.8 101.0 30.2 20.2 25.9 66.9 35.9 195.2 41.5 29.9 21.7 98.5 29.7 31.5 66.8 97.4 30.4 37.2 119.7 24.2 28.3 15.7 120.6 96.7 364.7 61.9 103.8 38.5 44.6 67.7 35.5 47.5 80.5 67.5 179.0 62.0 61.6 80.4 38.2 46.8 49.6 60.4 82.5 42.1 107.8 115.5 59.1 88.8 180.9 70.0 88.7 53.1 47.5 71.4 51.7 75.1 51.1 52.8 112.2 66.6 117.1 48.5 292.1 124.6 111.0 74.5 201.6 151.7 130.4 51.6 114.0 94.0 121.3 145.0 74.0 60.1 172.5 59.5 53.7 81.3 92.7 35.7 88.6 91.6 60.3 128.2 83.2 88.4 99.6 102.3 88.0 94.7 130.7 109.5 128.4 113.9 115.2 130.6 168.7 148.3 134.1 90.2 134.8 150.4 117.2 72.5 111.0 113.0 223.8 176.5 114.0 97.6 104.3 104.2 118.6 94.6 100.8 98.5 98.6 101.0 98.5 97.4 120.6 108.2 83.3 66.3 2.9 62.9 79.0 94.9 156.4 75.1 63.1 203.5 279.4 253.5 133.0 124.7 163.7 25.0 144.5 76.3 141.5 352.1 178.2 1145.8 380.4 114.9 101.6 106.2 199.9 2.9 240.5 166.2 96.9 71.4 126.0 82.4 150.0 111.0 282.5 124.3 33.7 3.2 163.3 126.1 72.9 63.8 2796.6 139.1 68.7 168.9 0.0 122.5 183.2 77.2 1.5 7.9 196.8 196.8 154.2 88.5 127.9 221.4 528.2 386.6 73.6 111.7 111.1 125.1 378.2 183.1 155.9 109.0 103.8 68.1 133.7 167.7 90.1 POM121L2 POM121-L ENSG00000158553 "POM121 transmembrane nucleoporin like 2" Q96KW2 6 27285903-27312170 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 68 "testis: 8.3" "Cell type enriched" "Detected in single" 6 "Spermatocytes: 3.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA046150 Uncertain NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA046150: AB_10960993" "unprognostic (2.45e-1)" "unprognostic (2.08e-1)" "unprognostic (1.22e-1)" "unprognostic (1.43e-2)" "unprognostic (5.88e-3)" "unprognostic (3.48e-2)" "unprognostic (1.93e-1)" "unprognostic (3.51e-2)" "unprognostic (2.03e-1)" 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 POMP "C13orf12, HSPC014, UMP1" ENSG00000132963 "Proteasome maturation protein" Q9Y244 13 28659104-28678959 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Chaperone "Ichthyosis, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026995 Approved Supported "Nuclear speckles" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nuclear speckles" "HPA026995: AB_1845546" "unprognostic (2.00e-1)" "unprognostic (3.56e-2)" "unprognostic (2.26e-1)" "unprognostic (3.15e-1)" "unprognostic (8.58e-2)" "prognostic unfavorable (2.05e-5)" "unprognostic (2.71e-3)" "unprognostic (2.50e-2)" "unprognostic (9.90e-2)" "unprognostic (4.35e-2)" "unprognostic (4.83e-2)" "unprognostic (4.93e-1)" "unprognostic (1.39e-3)" "unprognostic (1.70e-2)" "unprognostic (9.41e-2)" "unprognostic (1.03e-2)" "unprognostic (9.81e-2)" 78.9 71.6 77.5 62.9 78.5 66.4 66.7 82.1 101.1 45.1 77.8 66.6 57.0 44.4 78.9 68.7 43.4 46.2 126.3 78.1 83.6 94.1 110.9 65.6 65.4 82.2 83.4 32.9 46.6 51.7 41.7 100.3 83.2 46.6 66.3 56.2 45.1 50.7 175.6 48.5 58.4 57.2 83.6 61.2 54.9 70.0 81.0 64.6 51.4 114.6 70.1 74.0 46.9 86.3 103.4 124.9 129.9 153.1 145.3 161.3 120.3 232.1 203.8 225.5 179.5 245.7 228.7 181.7 136.3 178.6 241.7 150.3 170.7 179.3 307.5 137.7 131.9 171.7 130.1 191.1 203.0 209.6 136.0 131.2 181.9 162.5 149.5 122.3 181.6 139.7 222.2 72.5 291.5 182.5 178.4 295.6 226.1 319.0 146.1 169.6 199.3 122.2 259.6 160.7 152.1 117.1 104.0 147.4 162.2 161.5 103.1 238.5 166.2 108.7 111.2 172.3 195.5 61.5 118.5 255.3 129.2 139.8 243.6 146.4 155.3 101.7 99.9 210.8 88.7 136.4 101.6 113.2 190.8 137.6 71.8 101.9 135.1 95.3 213.9 223.4 132.3 165.2 77.5 78.5 82.1 101.1 78.1 83.6 82.2 83.4 83.2 83.6 81.0 86.3 527.4 131.4 114.2 17.3 218.5 409.8 345.1 1106.2 124.1 110.1 194.3 229.9 806.2 204.5 523.9 239.1 54.2 660.4 255.5 410.0 600.7 566.3 1156.6 266.7 235.8 486.2 228.7 271.5 23.4 699.5 974.0 281.8 128.9 293.0 207.3 181.6 434.1 538.7 780.7 97.6 22.4 315.0 585.9 431.0 673.7 533.7 201.0 407.1 300.6 29.0 612.6 294.7 228.6 13.6 26.1 755.1 414.0 233.6 228.1 443.5 491.8 922.5 472.8 121.8 322.1 193.8 494.6 625.5 240.3 230.1 416.3 972.4 202.7 234.7 335.5 494.3 POP4 RPP29 ENSG00000105171 "POP4 homolog, ribonuclease P/MRP subunit" O95707 19 29606283-29617237 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042748, HPA064577" Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - Unknown function" "Cluster 9: U-2 OS - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Nucleoli" "HPA042748: AB_10964774, HPA064577: " "unprognostic (5.88e-2)" "unprognostic (2.78e-2)" "unprognostic (7.21e-2)" "unprognostic (4.00e-3)" "unprognostic (4.50e-2)" "unprognostic (5.73e-2)" "prognostic unfavorable (3.31e-4)" "unprognostic (8.35e-2)" "unprognostic (2.37e-2)" "unprognostic (1.26e-1)" "unprognostic (2.20e-2)" "unprognostic (9.47e-2)" "unprognostic (5.84e-2)" "unprognostic (4.21e-1)" "unprognostic (1.77e-2)" "unprognostic (5.23e-3)" "unprognostic (8.08e-3)" 11.3 13.6 8.9 5.2 9.4 6.3 10.6 10.0 9.5 8.8 8.5 11.1 4.7 9.7 3.8 13.3 7.7 2.5 14.1 9.1 9.6 13.4 14.4 8.1 5.9 10.1 9.5 7.8 9.5 3.9 8.3 3.7 9.8 8.8 2.9 3.6 10.5 3.2 18.8 11.6 10.5 3.5 9.7 11.4 11.6 12.8 9.8 5.0 9.2 4.0 4.7 9.6 9.3 10.5 44.5 61.9 5.3 5.4 7.8 3.9 26.5 42.1 4.9 9.3 9.3 28.6 10.5 35.2 72.1 7.3 10.1 20.6 10.8 10.0 5.3 79.9 65.1 42.0 19.4 18.2 7.5 51.4 21.6 4.4 8.0 7.9 4.8 5.0 8.2 18.5 34.8 8.0 8.2 36.9 29.7 8.6 10.3 13.6 39.5 19.0 44.7 18.0 5.6 17.1 15.1 16.6 44.4 15.4 18.5 5.0 15.5 12.5 30.0 13.4 40.5 23.1 37.1 30.3 59.7 44.1 17.1 24.8 13.5 73.1 39.7 40.3 35.5 52.1 26.1 48.1 34.2 37.5 39.9 36.4 27.1 32.4 23.3 36.5 43.0 33.2 53.0 45.8 8.9 9.4 10.0 9.5 9.1 9.6 10.1 9.5 9.8 9.7 9.8 10.5 26.4 22.4 20.0 4.9 29.8 12.6 20.0 61.0 15.9 16.6 18.5 21.0 26.1 27.1 29.6 33.1 8.4 53.4 25.8 29.5 80.3 59.5 18.2 29.8 21.5 27.1 17.4 21.4 4.6 78.3 45.0 22.8 17.3 22.6 26.0 22.1 25.4 40.2 62.1 11.8 4.3 27.5 46.8 26.2 18.3 15.3 16.4 27.3 24.9 0.0 57.4 34.1 52.5 4.0 5.8 66.2 26.6 28.2 33.6 20.3 39.4 72.4 38.0 15.5 26.3 18.6 27.8 71.0 15.4 21.4 16.1 47.3 27.4 31.7 26.2 19.5 POSTN "OSF-2, periostin, PN" ENSG00000133110 Periostin Q15063 13 37562583-37598844 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" Heparin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 207.2;stomach 1: 174.6" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 295.7;Breast myoepithelial cells: 158.1;Endothelial cells: 134.6;Fibroblasts: 191.5;Smooth muscle cells: 151.5" "Cancer enhanced" "Detected in all" "breast cancer: 231.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "hTEC/SVTERT24-B: 490.2;SuSa: 440.5;U-138 MG: 619.3;U-2197: 427.2" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 6 "spinal cord: 87.9" HPA012306 Enhanced Approved "Nucleoplasm,Golgi apparatus" "Secreted to extracellular matrix" NA NA 660000000 "Cluster 31: Skin - Epidermis development" "Cluster 18: U-2197 - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus" Nucleoplasm "HPA012306: AB_1854827" "unprognostic (7.73e-2)" "unprognostic (1.44e-3)" "unprognostic (2.19e-2)" "unprognostic (2.57e-2)" "unprognostic (4.73e-2)" "unprognostic (2.22e-2)" "unprognostic (4.19e-3)" "prognostic unfavorable (2.93e-4)" "unprognostic (3.05e-3)" "unprognostic (7.10e-2)" "unprognostic (1.32e-2)" "unprognostic (5.93e-2)" "prognostic unfavorable (1.83e-7)" "prognostic unfavorable (4.86e-4)" "unprognostic (1.15e-1)" "unprognostic (1.20e-1)" "unprognostic (8.32e-3)" 71.4 5.2 4.5 23.8 0.1 0.3 84.0 0.0 4.4 20.3 2.9 61.3 5.1 53.2 13.0 20.5 83.5 64.3 83.2 3.0 0.0 28.1 13.0 45.1 12.8 0.9 0.0 3.6 2.2 21.6 2.4 60.9 2.0 16.1 84.9 0.0 17.7 44.8 10.6 207.2 15.0 66.6 0.0 1.1 174.6 3.4 0.1 5.8 19.1 29.9 3.9 91.4 10.7 0.4 0.0 0.0 71.0 1.6 85.0 51.0 0.2 23.1 0.0 5.5 0.7 0.0 1.4 0.1 0.0 18.7 0.1 0.0 0.7 0.0 2.6 0.0 0.0 0.0 0.0 0.0 14.2 0.2 0.1 90.8 0.0 490.2 1.9 15.9 0.7 0.0 0.0 0.0 11.8 0.0 0.3 0.4 4.1 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.4 0.2 0.1 0.6 0.0 440.5 0.9 0.0 0.0 619.3 0.3 427.2 3.4 0.1 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.1 0.0 4.4 3.0 0.0 0.9 0.0 2.0 0.0 0.1 0.4 46.7 6.4 10.6 0.7 0.3 295.7 1.3 51.5 0.0 0.0 2.9 158.1 22.8 0.0 18.7 0.0 0.0 2.5 1.0 0.0 0.0 0.0 0.5 0.5 9.8 134.6 0.0 0.0 1.5 0.0 0.2 191.5 0.0 0.3 3.8 0.0 22.5 0.6 3.7 0.0 36.8 0.0 24.4 0.0 27.0 1.1 6.5 0.8 30.2 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.7 0.4 0.4 0.0 0.0 5.6 0.0 0.0 0.7 151.5 1.3 0.9 0.2 48.4 3.4 2.3 49.3 0.0 0.3 POTEC "A26B2, CT104.6, DKFZp686J0529, POTE-18, POTE18" ENSG00000183206 "POTE ankyrin domain family member C" B2RU33 18 14507339-14543585 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 25 "testis: 2.5" "Cell type enriched" "Detected in some" 8 "Spermatocytes: 40.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (1.63e-1)" "unprognostic (9.88e-2)" "unprognostic (8.05e-2)" "unprognostic (1.64e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 2.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.5 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 40.1 4.9 0.0 0.0 0.3 0.0 0.0 0.1 0.1 POU4F2 "Brn-3b, BRN3B" ENSG00000151615 "POU class 4 homeobox 2" Q12837 4 146638893-146642474 "Predicted intracellular proteins, Transcription factors" "Apoptosis, Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 7.2" "Cell type enhanced" "Detected in single" "Rod photoreceptor cells: 1.0" "Not detected" "Not detected" "Group enriched" "Detected in some" 22 "medulla oblongata: 4.7;midbrain: 7.2;pons: 5.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SCLC-21H: 1.8" "Region enriched" "Detected in single" 6 "midbrain: 4.4" "Region enhanced" "Detected in some" "midbrain: 2.9" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 46: Photoreceptor cells - Phototransduction" "unprognostic (4.18e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.7 7.2 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.7 7.2 5.2 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 POU5F2 "FLJ25680, SPRM-1" ENSG00000248483 "POU domain class 5, transcription factor 2" Q8N7G0 5 93733220-93741600 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.7;testis: 1.9" "Cell type enhanced" "Detected in many" "Horizontal cells: 16.8;Rod photoreceptor cells: 14.4;Spermatocytes: 22.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "U-2 OS: 1.4" "Not detected" "Not detected" HPA077615 Enhanced Approved Nucleoplasm NA NA "Cluster 17: Basophils - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 9: U-2 OS - Unknown function" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "HPA077615: " "unprognostic (1.07e-1)" "unprognostic (2.78e-2)" "unprognostic (2.53e-1)" "unprognostic (1.17e-1)" "unprognostic (3.03e-1)" "unprognostic (9.17e-3)" "unprognostic (3.72e-2)" "unprognostic (5.87e-3)" "unprognostic (4.58e-1)" "unprognostic (1.49e-1)" "unprognostic (3.53e-2)" "unprognostic (3.84e-1)" "unprognostic (6.16e-9)" "unprognostic (1.87e-1)" "unprognostic (2.01e-1)" "unprognostic (2.21e-1)" "unprognostic (1.44e-3)" 0.0 0.0 0.6 0.1 0.8 0.4 0.2 1.7 0.9 0.0 0.2 0.1 0.2 0.1 0.2 0.0 0.0 0.1 0.0 0.5 0.3 0.1 0.1 0.0 0.2 1.0 0.5 0.1 0.0 0.0 0.0 0.1 1.0 0.1 0.1 1.0 0.1 0.1 0.1 0.4 0.2 0.0 0.3 0.1 0.2 1.9 1.0 0.1 0.2 0.0 0.1 0.0 0.0 1.7 0.1 0.1 0.3 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.1 0.0 0.1 0.2 0.2 0.0 0.1 0.1 0.1 0.2 0.2 0.2 0.0 0.2 0.2 0.1 0.2 0.1 0.1 0.1 0.0 0.2 0.2 0.3 0.1 0.1 0.1 0.3 0.1 0.1 0.1 0.1 0.3 0.2 0.0 0.1 0.3 0.3 0.2 0.1 0.0 0.1 0.1 0.2 0.1 0.1 1.4 0.2 0.1 0.2 0.1 0.2 0.1 0.2 0.1 0.3 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.3 0.1 0.1 0.4 0.2 0.0 0.1 0.2 0.0 0.6 0.8 1.7 0.9 0.5 0.3 1.0 0.5 1.0 0.3 1.0 1.7 2.3 3.2 2.2 0.0 4.3 2.2 2.6 1.8 0.0 10.7 2.8 1.5 0.4 1.5 1.0 1.8 6.2 1.0 4.7 1.3 0.0 1.6 2.7 3.0 3.2 2.5 3.0 3.2 0.0 0.9 0.9 2.1 1.1 3.3 8.2 5.8 2.5 0.9 1.1 16.8 0.0 0.3 0.0 2.4 6.2 7.6 4.7 2.4 1.8 0.0 3.3 2.9 11.3 0.0 0.0 2.1 1.2 1.5 1.8 2.1 1.8 0.5 2.1 14.4 0.0 3.4 1.8 22.3 2.3 0.7 2.7 0.5 4.8 4.6 1.2 2.3 PPA2 FLJ20459 ENSG00000138777 "Inorganic pyrophosphatase 2" Q9H2U2 4 105369077-105474067 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030888, HPA031671, HPA031672" Supported Approved Mitochondria NA NA 150000 "Cluster 44: Non-specific - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA030888: AB_2673646, HPA031671: AB_10603986, HPA031672: AB_2673988" "prognostic unfavorable (2.98e-4)" "unprognostic (5.64e-2)" "prognostic favorable (6.60e-4)" "unprognostic (9.26e-3)" "unprognostic (2.93e-2)" "unprognostic (5.10e-2)" "unprognostic (1.15e-1)" "unprognostic (2.44e-1)" "unprognostic (1.50e-1)" "unprognostic (1.20e-1)" "unprognostic (7.05e-2)" "unprognostic (9.54e-2)" "prognostic favorable (1.27e-11)" "unprognostic (3.69e-1)" "unprognostic (1.94e-1)" "unprognostic (2.00e-1)" "unprognostic (1.10e-1)" 7.4 12.8 23.8 9.0 24.6 22.0 12.0 24.3 53.7 7.4 29.5 17.4 14.2 7.4 12.5 10.8 8.4 8.0 27.5 23.7 26.3 20.7 14.8 7.5 8.3 24.4 24.3 5.8 11.8 11.7 7.7 7.4 24.5 13.3 14.0 13.6 13.8 5.7 27.6 12.2 13.8 6.8 24.0 9.9 12.6 6.3 25.4 7.0 11.5 35.5 8.7 8.1 6.7 26.6 20.6 8.5 18.5 32.3 11.3 9.1 12.9 10.2 15.7 14.6 9.9 22.2 30.4 15.6 14.5 9.7 11.3 9.5 39.2 18.7 17.0 23.6 11.8 13.5 13.7 19.9 9.3 36.7 13.6 9.7 19.6 9.9 7.9 15.4 14.6 28.4 22.3 22.0 12.5 26.2 32.5 26.6 13.9 42.4 28.3 28.2 10.9 17.9 49.7 14.7 17.8 10.7 7.8 48.9 19.0 10.7 24.8 32.1 6.9 9.2 19.2 8.9 20.0 19.0 27.3 18.4 17.5 18.6 14.1 27.0 20.9 15.4 21.0 30.1 18.6 28.5 21.7 23.7 49.9 22.6 21.1 23.9 9.5 36.4 26.4 25.9 23.4 23.5 23.8 24.6 24.3 53.7 23.7 26.3 24.4 24.3 24.5 24.0 25.4 26.6 26.7 9.6 67.3 86.2 37.6 50.0 82.4 205.0 38.1 29.7 64.8 40.9 63.3 45.8 126.2 33.1 16.7 119.0 25.9 73.3 264.1 114.0 113.7 42.3 35.3 36.3 65.7 70.2 138.2 120.1 98.5 31.1 37.2 42.3 45.6 26.4 24.3 64.2 83.5 21.9 134.6 104.6 142.4 42.9 86.1 126.4 27.7 47.1 76.5 74.9 50.5 39.2 30.9 169.9 145.7 65.0 90.4 32.4 41.9 68.1 112.2 285.4 90.7 22.6 39.5 46.3 43.6 50.8 10.8 59.1 57.7 84.7 34.3 72.1 138.0 94.6 PPFIBP2 Cclp1 ENSG00000166387 "PPFIA binding protein 2" Q8ND30 11 7513298-7657127 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 53.4;Extravillous trophoblasts: 56.2;Oligodendrocytes: 70.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 80.5;OE19: 100.4;RT4: 105.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001935, HPA003911" Enhanced Approved Mitochondria NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 21: OE19 - Mitochondria" "Cluster 44: Endometrium - Transcription" Mitochondria "HPA001935: AB_1079667, HPA003911: AB_1079666" "unprognostic (4.14e-2)" "unprognostic (7.04e-3)" "unprognostic (7.20e-3)" "unprognostic (5.79e-2)" "unprognostic (2.08e-1)" "prognostic favorable (2.32e-4)" "unprognostic (1.33e-1)" "prognostic favorable (2.26e-5)" "unprognostic (6.66e-3)" "unprognostic (2.90e-1)" "unprognostic (1.85e-1)" "unprognostic (1.17e-1)" "prognostic favorable (5.39e-8)" "unprognostic (1.78e-1)" "unprognostic (3.38e-1)" "unprognostic (2.52e-2)" "prognostic favorable (1.34e-5)" 10.8 11.7 21.5 12.0 34.2 7.6 16.6 24.9 24.4 14.7 51.3 22.4 26.4 6.7 33.5 27.3 17.2 15.7 13.0 21.8 26.2 19.0 35.4 11.6 15.2 27.4 29.8 14.3 9.4 66.5 4.8 21.0 29.0 18.2 26.5 2.8 54.8 32.8 33.4 33.2 26.0 5.4 20.6 11.1 44.1 31.5 31.7 4.5 37.5 21.4 25.0 29.5 21.8 43.8 2.0 32.7 5.3 3.1 6.1 0.4 80.5 7.1 16.1 4.1 4.0 26.7 4.6 9.7 3.7 4.1 15.1 14.2 21.0 2.1 3.7 3.9 2.4 0.0 0.3 17.1 8.4 19.6 9.3 10.7 7.6 0.0 4.5 0.4 1.5 2.0 0.9 26.5 4.0 15.9 0.0 19.0 37.8 100.4 0.1 3.3 0.1 17.4 0.1 105.0 1.5 12.4 1.1 28.9 21.9 14.6 4.0 14.7 0.5 1.9 2.8 6.4 0.7 14.1 11.1 8.3 2.3 4.5 13.0 3.4 9.1 6.5 3.1 11.2 2.3 12.7 5.0 2.1 8.3 7.2 6.6 5.2 4.2 2.6 14.4 0.6 1.1 5.2 21.5 34.2 24.9 24.4 21.8 26.2 27.4 29.8 29.0 20.6 31.7 43.8 1.7 16.0 13.6 3.9 21.2 5.5 18.7 4.5 10.2 1.5 10.1 7.7 5.2 11.5 13.7 14.7 18.8 9.1 1.6 29.8 9.8 5.8 53.4 6.7 4.8 3.2 3.6 0.0 3.8 9.6 56.2 7.7 40.2 35.7 7.0 0.6 1.1 17.3 7.1 0.0 6.0 23.2 8.2 10.4 7.2 47.2 4.7 11.3 16.0 17.8 15.7 1.7 3.1 49.8 70.5 6.9 22.8 7.2 9.0 13.4 26.8 19.7 7.5 3.3 0.0 5.7 10.2 22.2 2.6 10.7 9.9 4.8 2.0 1.2 18.0 18.6 PPIF "Cyp-D, hCyP3" ENSG00000108179 "Peptidylprolyl isomerase F" P30405 10 79347469-79355334 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Necrosis" "Isomerase, Rotamase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 370.9;Macrophages: 160.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 75.0" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077416 Supported Mitochondria NA NA 320000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 1: K-562 - Erythropoiesis" "Cluster 41: Macrophages - Immune response" Mitochondria "HPA077416: AB_2686840" "unprognostic (2.21e-1)" "unprognostic (5.48e-2)" "unprognostic (1.68e-1)" "unprognostic (1.72e-3)" "unprognostic (1.69e-1)" "unprognostic (3.16e-3)" "unprognostic (3.45e-1)" "unprognostic (4.33e-3)" "unprognostic (1.66e-1)" "unprognostic (1.97e-1)" "unprognostic (2.82e-1)" "unprognostic (9.37e-3)" "unprognostic (1.02e-3)" "unprognostic (1.23e-1)" "unprognostic (1.66e-1)" "unprognostic (1.69e-3)" "unprognostic (4.88e-2)" 62.7 227.7 42.7 42.8 48.4 168.8 42.4 57.9 69.6 27.6 63.7 50.0 36.3 14.0 7.2 66.0 22.9 19.5 119.1 38.1 45.2 63.3 174.9 29.1 32.3 49.0 56.2 19.3 86.9 77.6 18.3 27.1 48.8 18.8 52.4 8.9 39.5 45.5 99.5 71.9 31.3 21.0 50.6 58.7 98.2 35.0 57.1 28.3 26.0 133.6 55.5 60.0 35.1 60.8 220.4 90.6 62.3 123.5 57.0 73.6 79.8 124.2 161.2 265.7 249.6 213.5 102.7 224.8 68.0 87.4 188.6 127.8 195.3 115.4 410.5 72.2 186.4 352.8 87.5 380.7 96.4 245.7 80.4 173.2 81.3 264.5 262.3 86.5 47.5 86.4 351.6 268.3 91.6 111.7 64.1 204.2 53.0 99.6 500.6 109.8 96.4 114.7 103.9 200.0 124.1 92.0 63.6 253.8 97.9 40.5 111.4 187.2 43.5 116.1 106.3 137.9 242.0 124.7 137.7 181.9 114.5 313.9 32.0 15.2 34.3 18.0 10.4 27.5 10.9 19.1 9.1 9.6 43.3 7.7 8.1 7.9 75.0 9.0 10.4 5.4 10.0 16.6 42.7 48.4 57.9 69.6 38.1 45.2 49.0 56.2 48.8 50.6 57.1 60.8 8.4 6.4 6.8 7.2 32.7 42.6 30.2 23.8 31.3 4.0 41.8 40.8 124.6 14.3 14.4 12.9 6.2 99.4 26.4 39.9 92.0 42.1 14.5 12.4 24.0 10.1 21.6 37.0 4.1 28.0 127.1 25.1 78.0 15.5 13.4 73.4 6.1 98.5 91.1 8.4 5.7 69.5 18.3 40.3 370.9 14.1 6.2 160.8 35.6 4.7 32.0 13.0 5.2 5.5 15.0 39.8 26.6 6.0 48.7 41.4 21.3 41.2 12.6 5.2 19.7 18.2 28.6 14.8 22.5 52.9 37.6 142.3 23.9 60.2 81.1 34.2 PPM1D "PP2C-DELTA, Wip1" ENSG00000170836 "Protein phosphatase, Mg2+/Mn2+ dependent 1D" O15297 17 60600183-60666280 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle" "Hydrolase, Protein phosphatase" "Autism spectrum disorder, Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 68.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 34.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022277, HPA061848" Approved Supported Nucleoplasm,Nucleoli NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Transcription" Nucleoplasm Nucleoli "HPA022277: AB_1858839, HPA061848: " "unprognostic (1.48e-1)" "unprognostic (1.36e-2)" "prognostic favorable (3.52e-4)" "unprognostic (1.76e-1)" "unprognostic (1.02e-1)" "unprognostic (5.12e-2)" "prognostic unfavorable (4.27e-4)" "unprognostic (5.50e-2)" "unprognostic (1.70e-2)" "unprognostic (6.07e-2)" "unprognostic (2.52e-3)" "unprognostic (3.46e-2)" "unprognostic (1.95e-3)" "unprognostic (7.33e-2)" "unprognostic (1.58e-1)" "unprognostic (1.71e-2)" "unprognostic (1.98e-1)" 4.4 2.4 2.7 2.2 5.2 5.9 3.9 14.8 4.6 4.5 5.0 3.1 2.9 4.3 2.9 3.5 3.7 3.1 2.9 3.3 3.4 2.8 2.8 3.6 2.7 4.0 3.5 6.3 3.3 2.3 2.4 5.9 4.7 3.1 3.5 6.4 3.1 2.2 4.0 2.9 2.7 3.0 3.4 3.8 2.7 5.5 3.7 4.4 2.9 3.1 2.3 2.8 4.0 9.1 3.8 6.9 7.5 6.4 5.0 3.1 10.7 5.8 3.6 3.4 4.9 7.1 2.0 9.9 4.5 3.7 1.3 3.4 4.9 2.2 4.6 1.9 11.1 7.4 6.7 8.1 4.2 2.9 5.3 2.7 3.6 5.1 3.0 2.8 7.9 4.1 5.4 4.0 3.7 34.4 8.1 4.4 3.5 3.4 5.2 9.5 9.6 6.6 3.1 4.2 10.5 7.4 7.1 2.4 1.6 8.0 2.8 3.9 5.7 4.7 12.5 3.5 3.3 6.7 7.7 7.3 1.7 2.9 3.8 9.9 16.1 18.0 7.6 12.5 6.8 8.9 6.3 7.0 16.0 6.2 6.8 7.0 24.7 8.6 8.1 7.0 10.6 9.8 2.7 5.2 14.8 4.6 3.3 3.4 4.0 3.5 4.7 3.4 3.7 9.1 40.9 32.1 7.7 15.0 23.1 21.0 6.2 3.3 52.3 13.1 14.2 9.8 6.3 8.6 4.6 5.5 4.2 17.6 19.4 15.0 3.9 6.6 68.9 14.0 15.5 25.2 14.4 14.1 19.6 6.6 6.4 14.7 10.2 15.6 1.3 7.2 23.6 4.2 8.8 3.3 20.8 11.4 6.1 21.4 19.2 12.8 13.7 16.1 3.6 28.1 12.3 7.0 6.2 20.6 38.6 5.4 10.2 7.5 24.5 7.8 8.7 5.1 3.6 10.4 0.0 12.1 14.0 43.8 15.0 34.4 18.0 38.6 18.1 6.0 11.5 7.7 PPM1J "DKFZp434P1514, FLJ35951, MGC19531, PP2Czeta, PPP2CZ" ENSG00000155367 "Protein phosphatase, Mg2+/Mn2+ dependent 1J" Q5JR12 1 112709994-112715477 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "epididymis: 18.8;skeletal muscle: 68.4;skin 1: 18.1;testis: 63.8;tongue: 25.6" "Group enriched" "Detected in many" 4 "Early spermatids: 123.6;Late spermatids: 281.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 10 "plasmacytoid DC: 67.9" "Lineage enriched" "Detected in many" 15 "dendritic cells: 67.9" "Cell line enhanced" "Detected in many" "T-47d: 19.5" "Region enriched" "Detected in many" 7 "olfactory bulb: 27.3" "Low region specificity" "Detected in all" HPA046045 Uncertain Approved Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 6: T47d - Mammary gland" "Cluster 34: Spermatids - Unknown function" Vesicles "HPA046045: AB_2679516" "unprognostic (8.68e-2)" "unprognostic (5.65e-2)" "unprognostic (3.29e-2)" "unprognostic (2.59e-1)" "unprognostic (2.93e-3)" "unprognostic (2.34e-2)" "unprognostic (3.55e-2)" "unprognostic (3.74e-2)" "unprognostic (2.55e-1)" "unprognostic (9.30e-3)" "unprognostic (3.36e-2)" "unprognostic (7.22e-2)" "unprognostic (1.80e-2)" "unprognostic (1.27e-2)" "unprognostic (1.46e-1)" "unprognostic (2.28e-2)" "unprognostic (9.96e-4)" 1.1 2.6 6.3 1.0 6.6 0.7 2.2 5.9 6.5 2.3 3.8 1.2 0.6 1.9 18.8 4.6 2.8 1.0 8.7 5.8 5.7 7.8 0.7 1.6 3.3 5.2 7.8 2.3 1.7 5.5 2.6 0.5 4.6 3.3 0.6 6.9 2.8 2.1 68.4 18.1 1.4 1.3 4.5 1.4 1.2 63.8 9.1 2.3 3.1 25.6 2.2 1.1 4.0 3.9 2.7 0.1 1.5 1.7 0.8 1.5 1.1 0.3 0.7 0.3 1.0 1.2 0.8 0.4 0.4 0.8 0.8 4.9 1.1 4.6 0.4 0.0 2.6 0.8 0.2 0.2 0.9 0.0 0.2 1.7 3.0 0.9 4.6 1.0 2.1 0.2 1.0 0.0 1.2 2.9 0.0 0.0 1.6 1.4 2.3 0.1 0.1 0.0 2.7 0.1 0.8 0.2 0.6 4.3 1.3 2.2 19.5 0.0 1.1 0.3 2.8 0.0 0.2 0.1 0.0 0.0 2.3 0.6 2.6 0.0 0.3 0.0 0.0 1.5 0.1 0.7 0.0 0.1 7.1 0.7 0.0 0.0 0.0 0.0 4.3 67.9 0.0 0.8 6.3 6.6 5.9 6.5 5.8 5.7 5.2 7.8 4.6 4.5 9.1 3.9 1.2 0.0 0.5 0.3 2.0 2.2 4.7 8.7 10.2 5.7 4.2 4.6 5.8 0.0 2.7 1.8 10.4 1.0 41.3 0.7 9.8 3.2 123.6 3.2 0.3 1.5 0.0 0.0 1.8 4.3 1.4 1.1 1.1 0.6 0.0 5.6 0.7 0.1 0.7 0.0 1.5 0.9 2.0 1.3 11.5 281.6 3.1 2.0 0.0 0.0 1.6 25.4 0.0 0.0 0.2 2.1 2.4 2.6 0.0 6.7 0.3 0.6 1.8 9.1 6.6 1.1 2.8 2.8 16.9 3.5 2.8 0.5 0.9 3.2 0.8 2.9 PPP1R32 "C11orf66, FLJ32771, IIIG9" ENSG00000162148 "Protein phosphatase 1 regulatory subunit 32" Q7Z5V6 11 61481120-61490931 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 93.8" "Group enriched" "Detected in many" 4 "Early spermatids: 253.2;Late spermatids: 363.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA039068 Enhanced NA NA "Cluster 10: Basophils - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 25: Spermatids - Spermatogenesis" "HPA039068: AB_10672840" "unprognostic (1.70e-1)" "unprognostic (3.18e-3)" "unprognostic (4.48e-4)" "prognostic favorable (4.13e-4)" "unprognostic (2.23e-1)" "unprognostic (1.07e-2)" "unprognostic (1.50e-3)" "unprognostic (4.52e-2)" "unprognostic (2.81e-1)" "unprognostic (1.60e-1)" "unprognostic (1.04e-2)" "unprognostic (3.03e-2)" "unprognostic (9.44e-9)" "unprognostic (2.64e-1)" "unprognostic (2.71e-1)" "unprognostic (2.32e-1)" "unprognostic (1.75e-2)" 5.3 3.4 18.1 3.8 18.3 5.5 5.7 14.9 20.5 8.8 32.7 6.4 3.6 6.2 12.7 2.9 40.6 3.7 4.4 18.6 20.9 6.5 7.7 10.9 7.3 28.0 36.7 6.6 3.6 1.9 14.0 4.2 25.7 6.0 2.7 2.6 4.1 4.5 4.6 11.5 5.0 4.8 24.6 7.4 4.2 93.8 19.4 6.4 4.4 2.0 4.3 4.4 5.6 21.8 0.7 1.4 8.4 3.5 3.7 5.5 1.1 1.7 1.3 1.1 0.9 0.4 7.4 1.6 2.3 0.8 0.4 0.9 1.2 0.6 2.1 2.7 1.7 2.1 0.4 0.2 3.6 1.4 1.6 5.8 2.1 0.4 6.2 6.7 0.8 6.0 0.8 5.0 0.5 1.9 2.1 3.0 0.6 1.4 0.8 4.1 0.2 0.5 1.1 0.3 0.9 2.0 0.3 3.7 0.6 0.7 4.3 4.6 3.1 0.4 1.7 1.3 0.3 8.0 2.3 1.0 0.9 6.0 0.7 1.5 1.1 0.7 1.0 1.3 1.0 0.4 0.6 0.2 0.5 0.4 0.4 1.3 2.0 0.8 0.4 0.4 0.8 0.9 18.1 18.3 14.9 20.5 18.6 20.9 28.0 36.7 25.7 24.6 19.4 21.8 1.5 3.2 1.1 6.8 0.5 0.1 0.8 2.5 0.0 0.5 4.2 4.1 1.3 0.0 6.1 5.5 0.0 1.0 2.2 0.7 31.3 0.5 253.2 27.9 0.9 1.5 3.5 0.0 2.2 1.6 0.3 1.1 0.0 0.8 0.0 1.7 0.4 10.8 0.8 0.0 1.1 1.0 4.1 1.8 1.2 363.8 3.7 0.8 0.0 1.9 1.3 3.0 2.1 1.5 2.7 0.6 1.1 4.1 0.9 1.8 2.1 20.3 72.1 0.2 0.0 0.7 2.6 8.1 1.9 0.1 0.3 0.4 0.7 0.6 0.9 0.8 PPP1R42 "dtr, LRRC67, TLLR" ENSG00000178125 "Protein phosphatase 1 regulatory subunit 42" Q7Z4L9 8 66964099-67056604 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "fallopian tube: 4.9;testis: 8.7" "Group enriched" "Detected in many" 5 "Early spermatids: 68.1;Endometrial ciliated cells: 79.3;Respiratory ciliated cells: 127.2;Spermatocytes: 111.8" "Cancer enhanced" "Detected in some" "glioma: 0.7" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA024313, HPA027983, HPA028628" Uncertain NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 49: Ciliated cells - Cilium organization" "HPA024313: AB_1853053, HPA027983: AB_10599300, HPA028628: AB_2250064" "unprognostic (8.03e-3)" "unprognostic (5.45e-2)" "unprognostic (4.18e-2)" "unprognostic (2.32e-1)" "unprognostic (1.92e-1)" "unprognostic (5.42e-2)" "unprognostic (1.99e-2)" "unprognostic (1.03e-1)" "unprognostic (3.61e-3)" "unprognostic (6.86e-2)" "unprognostic (8.58e-3)" "unprognostic (1.44e-1)" "unprognostic (1.12e-1)" "unprognostic (8.07e-2)" "unprognostic (2.33e-1)" 0.0 0.1 0.3 0.0 0.3 0.0 0.0 0.2 0.4 0.1 1.4 0.0 0.0 0.1 0.3 0.0 4.9 0.0 0.0 0.4 0.4 0.2 0.0 0.3 0.0 1.4 1.2 0.0 0.0 0.3 0.2 0.0 0.9 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 8.7 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.2 0.4 0.4 0.4 1.4 1.2 0.9 0.9 0.5 0.6 0.0 0.0 1.1 11.8 0.0 0.0 0.0 6.0 0.0 0.1 0.7 1.0 0.9 0.0 10.8 5.5 0.0 0.0 0.0 0.0 3.9 0.5 68.1 79.3 0.7 0.2 0.0 0.0 3.2 0.0 0.0 0.6 0.0 1.0 0.0 0.3 0.0 0.0 0.0 1.7 2.8 0.0 6.1 0.0 0.0 16.5 0.6 0.3 0.0 1.0 0.0 3.6 0.0 3.5 2.9 0.1 0.0 1.9 0.0 0.0 0.0 1.9 127.2 3.5 6.6 0.0 1.4 111.8 3.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 PPP1R9A "FLJ20068, KIAA1222, Neurabin-I" ENSG00000158528 "Protein phosphatase 1 regulatory subunit 9A" Q9ULJ8 7 94907202-95296415 "Plasma proteins, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Actin-binding, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 20.1" "Cell type enhanced" "Detected in many" "Astrocytes: 294.1;Excitatory neurons: 262.8;Inhibitory neurons: 201.5;Oligodendrocyte precursor cells: 593.1;Oligodendrocytes: 308.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "basophil: 6.8;NK-cell: 10.3" "Group enriched" "Detected in many" 9 "granulocytes: 6.8;NK-cells: 10.3" "Cell line enhanced" "Detected in many" "HAP1: 12.2;RH-30: 11.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027726, HPA075591" Approved Approved "Plasma membrane" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 36: HEL - Hemostasis" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane" "HPA027726: AB_1855653, HPA075591: AB_2732296" "unprognostic (1.05e-1)" "unprognostic (6.59e-2)" "unprognostic (5.90e-2)" "unprognostic (1.63e-2)" "unprognostic (1.35e-1)" "unprognostic (1.12e-1)" "unprognostic (8.62e-2)" "unprognostic (6.19e-2)" "unprognostic (1.45e-1)" "prognostic favorable (7.17e-4)" "unprognostic (2.26e-2)" "unprognostic (1.89e-1)" "prognostic favorable (8.63e-6)" "unprognostic (2.74e-1)" "unprognostic (4.85e-2)" "unprognostic (8.47e-2)" "unprognostic (8.79e-3)" 1.7 7.0 13.0 0.9 20.1 0.2 4.9 6.0 14.5 2.7 0.3 8.2 1.7 3.0 4.9 1.6 5.7 2.4 5.2 14.4 7.5 4.7 0.4 3.7 0.3 5.9 6.9 3.3 8.8 6.7 4.6 2.5 8.0 2.3 3.8 18.5 9.6 2.8 4.9 0.5 2.2 2.2 6.6 1.8 4.9 6.7 10.2 0.5 6.6 4.9 0.3 2.6 0.5 13.9 0.0 11.0 6.6 7.6 0.0 0.0 5.3 0.5 0.1 1.0 0.8 6.1 3.7 0.0 9.0 0.5 0.6 0.0 12.2 0.0 1.2 0.0 4.5 11.4 4.5 7.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.8 4.8 0.1 0.0 5.5 4.9 1.8 0.0 11.8 0.0 10.7 9.2 7.3 7.4 0.0 0.9 1.4 4.0 2.1 0.0 0.0 0.1 4.4 0.1 4.0 7.3 11.5 0.0 0.2 0.0 0.9 6.8 0.0 0.4 0.0 0.0 0.2 0.7 0.0 0.0 0.0 1.0 0.0 0.0 0.0 10.3 0.1 0.3 0.0 0.1 13.0 20.1 6.0 14.5 14.4 7.5 5.9 6.9 8.0 6.6 10.2 13.9 4.5 41.7 66.6 294.1 2.4 0.4 0.9 0.0 0.6 58.2 24.4 12.2 127.7 18.6 16.5 47.8 56.3 21.6 3.3 15.7 3.9 25.1 17.9 40.3 4.5 6.8 38.9 2.5 262.8 7.0 3.1 9.4 21.4 57.1 5.7 39.5 7.9 1.5 1.7 1.7 201.5 15.0 4.1 0.6 0.3 15.3 2.5 0.8 7.2 41.2 0.0 46.9 3.1 593.1 308.4 6.6 14.4 0.7 2.7 4.8 1.8 9.6 20.6 88.9 0.0 118.4 9.2 25.1 12.6 0.5 0.9 33.1 1.7 22.9 15.7 2.6 PPP1R9B "PPP1R6, PPP1R9, SPINO, Spn" ENSG00000108819 "Protein phosphatase 1 regulatory subunit 9B" Q96SB3 17 50133737-50150677 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Actin-binding, Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 96.7" "Cell type enhanced" "Detected in many" "Kupffer cells: 48.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022461 Approved NA NA 420000000 "Cluster 52: Eosinophils - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 44: HDLM-2 - Immune response" "Cluster 57: B-cells - Immune response" "CAB022461: " "unprognostic (4.71e-1)" "unprognostic (3.77e-2)" "unprognostic (3.82e-2)" "unprognostic (1.23e-1)" "unprognostic (2.02e-1)" "unprognostic (2.17e-1)" "unprognostic (1.74e-3)" "unprognostic (1.99e-1)" "unprognostic (4.09e-2)" "unprognostic (2.80e-1)" "prognostic favorable (3.11e-4)" "unprognostic (8.50e-2)" "unprognostic (1.57e-2)" "unprognostic (1.49e-2)" "unprognostic (4.17e-2)" "unprognostic (1.71e-2)" "unprognostic (4.29e-1)" 23.5 30.0 61.4 28.6 58.6 33.7 20.2 39.3 96.7 25.4 4.6 17.6 14.9 22.0 8.4 28.9 19.6 15.5 24.3 90.2 30.3 23.3 11.9 39.9 36.8 25.7 40.1 27.8 18.3 15.2 20.6 14.6 24.0 21.5 8.9 7.9 17.6 10.6 11.8 24.2 30.2 11.8 22.2 52.4 17.8 24.0 47.7 22.5 22.0 14.8 28.0 20.4 22.6 48.9 25.9 45.2 24.0 60.5 31.2 19.8 56.9 36.4 33.1 31.5 22.9 38.3 19.9 48.6 57.8 42.2 30.7 25.2 24.9 25.8 19.6 125.7 37.2 79.9 35.4 26.2 30.3 35.1 121.2 22.2 44.4 34.6 21.7 60.5 31.2 15.4 43.0 35.7 21.0 47.7 13.0 50.2 9.4 33.0 40.9 26.5 32.5 34.6 21.6 15.0 15.1 44.5 23.0 35.6 29.5 19.3 47.7 68.8 25.5 66.4 48.7 46.0 48.8 65.4 16.2 35.2 30.5 34.8 32.4 4.2 1.8 2.9 1.3 1.6 1.1 1.6 1.0 0.9 1.4 2.0 0.4 0.9 4.1 2.2 2.0 2.0 0.5 0.8 61.4 58.6 39.3 96.7 90.2 30.3 25.7 40.1 24.0 22.2 47.7 48.9 18.1 0.0 2.2 6.2 23.6 23.6 3.6 5.8 13.6 18.8 7.8 5.3 7.7 4.3 3.2 16.5 2.1 2.3 29.0 10.9 5.9 9.7 2.6 4.0 9.5 20.9 12.0 20.2 6.6 9.1 3.5 10.5 5.6 6.3 2.5 9.6 18.2 8.7 27.7 16.8 6.5 10.8 10.2 48.6 34.6 5.1 20.2 30.2 12.4 2.8 42.1 3.2 34.0 2.5 2.7 9.1 10.2 15.4 15.4 7.8 18.1 9.8 3.4 2.6 13.1 7.0 9.1 5.5 5.7 16.9 22.4 1.0 14.9 10.0 10.7 5.4 PPP2R1B "PP2A-Abeta, PR65B" ENSG00000137713 "Protein phosphatase 2 scaffold subunit Abeta" P30154 11 111726908-111766389 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 170.7" "Cell type enhanced" "Detected in all" "Early spermatids: 306.1;Late spermatids: 160.7;Spermatocytes: 135.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 173.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004034, HPA018908" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Plasma membrane, Cytosol" "CAB004034: AB_490763, HPA018908: AB_1855655" "unprognostic (8.37e-2)" "unprognostic (3.87e-2)" "unprognostic (4.84e-3)" "unprognostic (3.27e-3)" "unprognostic (3.43e-1)" "unprognostic (4.93e-2)" "prognostic favorable (3.80e-4)" "unprognostic (4.58e-1)" "unprognostic (8.20e-3)" "unprognostic (2.26e-1)" "unprognostic (1.72e-1)" "unprognostic (8.41e-2)" "unprognostic (1.25e-3)" "unprognostic (1.25e-1)" "unprognostic (5.30e-1)" "unprognostic (2.12e-2)" "unprognostic (1.22e-1)" 58.5 10.5 11.3 14.1 18.0 16.2 21.5 20.0 13.9 13.0 17.3 14.7 13.9 8.7 8.1 12.6 8.0 13.4 6.3 11.7 13.8 14.6 170.7 8.8 12.1 14.7 13.7 13.3 33.2 12.9 10.7 9.2 14.2 7.7 14.7 8.5 9.6 6.1 9.6 10.7 15.2 7.8 10.6 6.3 22.3 54.0 13.8 15.9 10.6 8.9 14.1 12.2 7.4 20.7 38.4 25.1 35.6 24.2 34.9 18.7 35.8 37.2 25.9 27.0 24.6 86.0 39.3 48.3 27.1 24.1 25.6 35.4 53.4 30.5 34.3 33.7 16.6 47.2 14.5 37.8 17.3 55.7 36.1 21.5 18.1 30.6 22.2 19.1 33.8 49.7 58.3 62.3 30.1 12.4 60.8 22.6 43.8 41.4 27.3 45.9 23.6 58.6 40.2 41.9 11.6 31.4 33.1 30.2 6.1 38.3 35.0 20.6 36.7 31.3 37.8 15.6 23.9 6.6 17.4 173.8 11.1 63.9 40.7 6.1 10.1 10.4 13.0 11.7 12.7 10.0 12.9 12.1 14.9 12.5 11.2 12.0 2.6 15.3 11.4 6.4 15.0 12.2 11.3 18.0 20.0 13.9 11.7 13.8 14.7 13.7 14.2 10.6 13.8 20.7 21.2 19.2 10.5 63.3 11.0 14.3 11.0 12.0 18.2 5.4 14.1 8.5 3.2 15.7 13.4 12.9 8.4 13.5 11.0 23.8 13.7 18.7 306.1 29.6 13.4 20.2 15.6 32.4 23.8 22.9 20.3 12.3 15.3 46.1 8.2 34.3 9.3 89.4 9.5 1.7 14.5 11.5 22.4 5.8 9.2 160.7 6.5 7.5 8.8 17.8 8.9 9.9 7.2 26.2 49.1 23.6 9.0 7.5 9.0 10.9 16.2 17.6 16.8 11.0 13.1 14.5 14.4 135.9 20.8 12.0 14.6 17.6 11.0 9.7 13.9 15.0 PPP2R2B "B55beta, PR52B, PR55-BETA, SCA12" ENSG00000156475 "Protein phosphatase 2 regulatory subunit Bbeta" Q00005 5 146580742-147084784 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Apoptosis "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 77.1;retina: 43.0" "Cell type enhanced" "Detected in many" "Astrocytes: 1539.0;Excitatory neurons: 846.0;Inhibitory neurons: 788.8;Late spermatids: 876.4;Oligodendrocyte precursor cells: 1035.4;Oligodendrocytes: 4480.1" "Cancer enriched" "Detected in some" 8 "glioma: 7.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "gdT-cell: 5.2;MAIT T-cell: 4.1;memory CD4 T-cell: 2.4;memory CD8 T-cell: 6.2;naive CD8 T-cell: 3.8;NK-cell: 2.9;T-reg: 3.4" "Group enriched" "Detected in many" 9 "NK-cells: 2.9;T-cells: 6.2" "Cell line enhanced" "Detected in some" "HaCaT: 7.2;HDLM-2: 24.2;RT4: 12.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038118, HPA042122, HPA042770" Approved Uncertain Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 58: Brain - Synaptic function" "Cluster 44: HDLM-2 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "HPA038118: AB_10697238, HPA042122: AB_2677859, HPA042770: AB_2678155" "unprognostic (4.54e-5)" "unprognostic (1.74e-1)" "unprognostic (1.21e-1)" "unprognostic (2.80e-4)" "unprognostic (2.48e-1)" "unprognostic (1.44e-1)" "unprognostic (2.76e-1)" "unprognostic (1.84e-2)" "unprognostic (2.68e-1)" "unprognostic (3.20e-2)" "unprognostic (9.73e-4)" "unprognostic (4.51e-2)" "unprognostic (1.49e-8)" "unprognostic (2.02e-1)" "unprognostic (3.67e-1)" "unprognostic (5.48e-5)" "unprognostic (1.14e-4)" 1.3 7.8 53.9 0.9 71.4 1.9 0.8 44.7 77.1 1.2 6.0 6.5 1.0 0.4 0.5 1.3 3.6 1.8 2.5 57.8 53.9 3.7 0.7 0.8 1.7 50.7 56.3 0.4 1.9 2.8 14.8 0.7 50.4 1.9 1.9 43.0 1.0 1.0 0.3 3.4 2.2 1.3 50.7 1.8 1.1 18.9 71.6 0.8 3.1 0.3 0.8 7.5 2.0 73.9 0.2 0.0 1.3 2.0 0.2 0.0 0.4 0.7 0.3 0.7 0.2 2.3 1.9 0.2 0.2 0.1 0.0 7.2 0.5 0.4 1.8 24.2 0.4 0.4 4.8 0.6 0.4 0.1 0.4 0.2 1.2 0.0 0.4 0.8 0.3 0.7 0.7 0.5 0.9 0.3 0.2 0.1 2.3 0.0 0.9 1.6 0.2 0.0 1.9 12.5 1.3 0.2 0.3 0.0 0.3 1.4 0.7 0.0 0.4 0.1 0.3 1.7 0.6 0.1 0.4 0.2 0.9 1.9 2.0 0.5 0.0 0.0 5.2 0.0 4.1 0.1 2.4 6.2 0.0 0.0 0.6 3.8 0.1 2.9 0.1 0.0 3.4 1.4 53.9 71.4 44.7 77.1 57.8 53.9 50.7 56.3 50.4 50.7 71.6 73.9 0.5 3.2 1.8 1539.0 0.3 2.0 1.1 2.3 4.6 90.5 0.5 3.6 1.6 10.0 0.9 9.2 150.1 18.9 30.2 0.0 21.5 1.7 295.3 1.0 0.1 2.0 13.1 1.3 846.0 0.0 0.3 1.1 1.1 0.4 0.0 0.0 0.0 0.0 0.9 47.1 788.8 0.0 0.0 1.2 4.7 876.4 3.4 1.4 5.4 58.1 0.3 45.0 57.7 1035.4 4480.1 0.6 0.0 2.2 3.3 1.0 0.0 5.5 0.1 275.4 0.0 0.7 11.0 4.8 2.2 1.6 1.4 5.3 31.0 0.1 0.0 0.9 PPP2R3C "C14orf10, FLJ20644, G4-1, G5PR" ENSG00000092020 "Protein phosphatase 2 regulatory subunit B''gamma" Q969Q6 14 35085467-35122517 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cone-rod dystrophy, Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 489.7;Late spermatids: 233.5;Spermatocytes: 239.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040835, HPA058834" Approved Supported "Nucleoplasm,Golgi apparatus,Cytosol" No No "Cluster 31: Non-specific - Inflammatory response" "Cluster 10: Brain - Neuronal signaling" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "Golgi apparatus, Cytosol" "HPA040835: AB_10794152, HPA058834: AB_2683831" "unprognostic (1.41e-1)" "unprognostic (1.52e-1)" "unprognostic (1.15e-1)" "unprognostic (7.32e-3)" "unprognostic (5.33e-2)" "unprognostic (9.73e-2)" "unprognostic (1.10e-3)" "unprognostic (3.05e-1)" "unprognostic (7.85e-2)" "unprognostic (9.48e-3)" "unprognostic (1.17e-2)" "unprognostic (1.91e-1)" "unprognostic (2.18e-1)" "unprognostic (3.04e-2)" "unprognostic (3.15e-3)" "unprognostic (8.55e-2)" "unprognostic (8.29e-2)" 19.9 15.5 23.5 23.9 25.0 42.8 17.1 24.4 41.6 18.1 23.3 18.6 21.0 16.2 16.4 12.5 14.0 18.6 22.9 23.8 25.6 14.4 16.1 17.7 31.0 25.3 24.4 15.9 10.2 17.0 17.6 18.8 25.6 17.1 20.3 15.4 13.5 14.1 24.9 7.1 22.5 21.0 24.9 24.4 16.2 71.6 24.4 26.4 12.4 25.7 25.9 22.3 10.4 27.5 41.2 21.8 41.7 33.9 32.4 54.5 29.6 33.0 32.0 41.0 48.0 18.1 32.2 47.2 13.4 33.9 15.5 17.6 20.0 13.8 60.5 47.8 19.3 26.2 11.9 65.2 43.3 51.2 51.7 41.9 14.4 29.0 19.7 24.0 55.7 26.2 25.7 46.3 57.4 28.4 46.4 43.1 37.1 27.4 24.3 50.2 27.1 32.8 15.8 24.1 39.9 37.5 41.7 27.6 57.8 19.9 17.9 57.0 47.9 41.3 17.3 36.0 34.9 44.8 52.4 92.8 22.8 47.9 48.1 66.5 41.6 86.9 23.4 52.5 27.0 31.0 24.8 29.5 36.1 33.1 22.0 26.9 76.9 33.1 42.7 16.3 40.8 34.0 23.5 25.0 24.4 41.6 23.8 25.6 25.3 24.4 25.6 24.9 24.4 27.5 35.5 16.0 24.7 32.7 40.2 11.5 23.3 31.7 9.6 15.9 18.8 14.7 26.3 17.2 25.8 20.2 4.2 19.4 48.1 29.1 33.2 31.2 489.7 23.1 28.1 33.8 31.2 69.7 28.3 36.1 26.2 26.5 19.9 21.7 33.7 31.3 34.6 22.8 61.3 8.4 30.4 26.8 32.6 49.7 36.3 233.5 28.3 42.6 28.4 24.4 71.5 28.7 46.4 36.2 58.8 49.2 22.3 30.5 37.4 24.8 37.8 43.2 25.1 21.5 32.9 24.0 43.1 239.2 58.6 19.6 13.5 34.8 45.2 36.2 24.6 30.5 PPP3R2 PPP3RL ENSG00000188386 "Protein phosphatase 3 regulatory subunit B, beta" Q96LZ3 9 101591604-101595021 "FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 161 "testis: 80.8" "Group enriched" "Detected in some" 38 "Early spermatids: 399.2;Late spermatids: 198.3;Spermatocytes: 600.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047157 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 66: Spermatocytes - Spermatogenesis" "Plasma membrane" Cytosol "HPA047157: AB_2679960" "unprognostic (8.81e-2)" "unprognostic (2.65e-1)" 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 80.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.5 0.1 0.0 0.4 0.1 0.4 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 399.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 198.3 10.5 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.1 0.2 600.6 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PPP4R3A "FLFL1, FLJ20707, KIAA2010, MSTP033, PP4R3, SMEK1, smk-1, smk1" ENSG00000100796 "Protein phosphatase 4 regulatory subunit 3A" Q6IN85 14 91457508-91510554 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002568, HPA063917" Approved Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 59: Non-specific - Transcription" Nucleoplasm "Nuclear speckles, Cytosol" "HPA002568: AB_1079207, HPA063917: AB_2685153" "unprognostic (5.51e-2)" "unprognostic (2.93e-2)" "unprognostic (3.26e-1)" "unprognostic (1.40e-1)" "unprognostic (4.40e-2)" "unprognostic (9.95e-3)" "unprognostic (4.10e-2)" "unprognostic (5.71e-3)" "unprognostic (1.05e-1)" "unprognostic (8.34e-3)" "unprognostic (1.33e-1)" "unprognostic (3.85e-2)" "unprognostic (3.07e-1)" "unprognostic (1.13e-1)" "unprognostic (2.57e-1)" "unprognostic (1.57e-1)" "unprognostic (4.53e-2)" 19.3 13.5 14.4 18.2 14.5 50.0 19.6 16.6 15.2 19.1 16.2 21.2 17.2 20.0 15.9 21.4 20.4 12.3 16.2 12.6 13.3 18.3 23.7 20.2 28.3 13.6 14.2 22.0 19.8 16.8 14.8 17.5 13.7 18.4 18.5 10.9 20.8 13.1 24.5 25.4 24.4 15.0 12.7 24.1 20.6 22.3 14.5 27.4 17.7 16.7 25.4 19.5 19.4 16.9 24.5 41.4 34.1 27.1 22.5 20.9 60.9 23.2 21.4 24.5 24.6 35.2 32.1 63.1 30.2 19.2 15.0 27.8 36.6 28.9 39.8 52.0 19.7 32.5 25.7 24.5 26.3 59.1 33.1 15.1 50.4 19.7 31.1 20.1 26.7 29.4 33.5 36.2 33.1 52.1 42.8 38.0 31.2 46.5 29.8 54.0 40.6 26.5 30.3 41.5 41.6 25.4 35.3 77.0 32.5 33.6 39.4 37.8 28.0 19.2 20.6 21.1 26.8 36.0 67.0 69.3 25.2 31.8 34.7 6.2 1.9 2.9 4.9 2.6 6.6 4.6 4.5 4.4 2.1 7.4 5.6 4.8 2.5 9.0 3.7 5.0 6.9 2.6 14.4 14.5 16.6 15.2 12.6 13.3 13.6 14.2 13.7 12.7 14.5 16.9 44.1 32.1 48.3 0.0 83.0 0.0 46.7 0.0 58.1 27.9 35.9 23.5 0.0 32.9 30.3 46.0 20.9 33.9 91.8 21.1 29.4 21.2 13.0 86.9 46.5 33.3 13.3 47.5 0.0 25.1 29.0 27.3 45.3 70.7 20.2 39.8 28.9 51.8 25.8 32.0 0.0 28.2 0.0 48.7 0.0 8.5 37.6 70.7 0.0 0.0 41.8 21.0 44.3 0.0 0.0 27.8 25.7 42.5 75.8 56.6 37.3 23.5 16.8 27.3 26.3 45.9 27.1 91.0 59.9 58.0 0.0 44.3 80.1 33.0 25.8 75.2 PRAC2 "C17orf93, HOXB-AS5, HOXB13-AS1, NCRNA00253" ENSG00000229637 "PRAC2 small nuclear protein" D3DTV9 17 48723185-48724758 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 4 "intestine: 9.7;prostate: 13.3" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 36.2;Distal enterocytes: 17.5;Early spermatids: 32.9;Enteroendocrine cells: 31.9;Intestinal goblet cells: 15.5;Late spermatids: 60.5;Prostatic glandular cells: 20.2;Undifferentiated cells: 22.7;Urothelial cells: 30.1" "Cancer enriched" "Detected in many" 8 "prostate cancer: 26.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "PC-3: 49.3;REH: 20.0" "Intracellular and membrane" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (1.22e-2)" "unprognostic (1.45e-1)" "unprognostic (4.26e-2)" "unprognostic (2.04e-1)" "unprognostic (1.63e-2)" "unprognostic (9.98e-2)" "unprognostic (3.27e-2)" "unprognostic (9.77e-2)" "unprognostic (8.97e-2)" "unprognostic (1.01e-1)" "unprognostic (1.82e-1)" "unprognostic (1.82e-1)" 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 13.3 9.7 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 2.4 2.5 0.0 0.0 0.3 0.0 0.7 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 1.9 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.1 0.0 6.5 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 1.2 49.3 20.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5.2 0.0 2.8 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 36.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.5 0.0 0.0 32.9 0.0 0.0 0.1 31.9 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 15.5 0.0 0.0 0.3 60.5 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.5 0.4 0.0 20.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 22.7 30.1 PRB3 PRG ENSG00000197870 "Proline rich protein BstNI subfamily 3" Q04118 12 11265924-11269805 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 1919 "salivary gland: 14225.0" "Cell type enhanced" "Detected in some" "Early spermatids: 8.8;Endometrial ciliated cells: 1.7;Glandular and luminal cells: 1.7;Late spermatids: 3.4" "Cancer enhanced" "Detected in some" "head and neck cancer: 2.0;lung cancer: 1.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "NTERA-2: 2.2" "Secreted to digestive system" NA NA 27000000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 5: NTERA-2 - Transcription" "Cluster 29: Early spermatids - Spermatogenesis" "unprognostic (4.12e-2)" "unprognostic (1.34e-1)" "unprognostic (1.05e-3)" "unprognostic (1.51e-1)" "unprognostic (7.46e-3)" "unprognostic (4.12e-2)" "unprognostic (9.65e-2)" "unprognostic (1.94e-2)" "unprognostic (8.27e-2)" "unprognostic (9.98e-2)" "unprognostic (2.35e-1)" "unprognostic (2.11e-2)" "unprognostic (1.04e-1)" "unprognostic (2.86e-1)" "unprognostic (1.06e-2)" 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 14225.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.2 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 8.8 1.7 0.3 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 PRC1 ASE1 ENSG00000198901 "Protein regulator of cytokinesis 1" O43663 15 90966040-90995629 "Predicted intracellular proteins" "Cell cycle, Cell division" Oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 89.9;testis: 55.0" "Cell type enhanced" "Detected in many" "Erythroid cells: 142.9;Extravillous trophoblasts: 68.3;Spermatocytes: 136.4;Spermatogonia: 74.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 34.4" "Lineage enriched" "Detected in many" 4 "granulocytes: 34.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA034521, HPA048816" Enhanced Supported "Nucleoplasm,Plasma membrane,Microtubules,Cytokinetic bridge,Midbody" Yes Yes "Cluster 38: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Microtubules, Cytokinetic bridge, Midbody" Nucleoplasm "HPA034521: AB_10670169, HPA048816: " "unprognostic (1.14e-1)" "unprognostic (3.98e-2)" "unprognostic (9.21e-2)" "unprognostic (1.75e-3)" "unprognostic (2.39e-1)" "unprognostic (3.43e-2)" "prognostic unfavorable (2.11e-4)" "unprognostic (1.24e-3)" "unprognostic (3.86e-3)" "unprognostic (1.65e-2)" "prognostic unfavorable (2.76e-5)" "unprognostic (2.49e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.09e-2)" "unprognostic (1.79e-1)" "unprognostic (7.90e-2)" "unprognostic (3.92e-2)" 7.4 6.2 6.4 10.0 6.1 89.9 6.4 10.3 8.4 8.1 5.0 16.3 10.6 5.7 2.3 37.6 6.0 3.0 6.9 5.6 4.9 5.6 4.8 9.0 16.9 4.8 5.2 8.1 8.9 2.6 3.6 15.3 5.2 4.9 16.5 4.9 9.5 1.5 4.1 20.1 13.0 9.4 4.9 12.5 11.7 55.0 4.2 43.0 4.3 2.3 24.9 4.8 13.7 5.6 167.9 199.9 164.8 113.6 16.8 28.7 87.5 237.8 139.3 257.2 195.3 134.6 158.5 65.5 91.4 151.9 156.9 220.9 188.8 101.2 240.6 118.7 206.4 135.6 263.5 123.5 4.1 71.4 109.0 7.7 12.8 145.8 146.9 56.6 146.4 100.5 114.0 132.4 241.1 144.4 66.9 98.5 66.6 216.4 84.9 69.7 205.1 86.3 115.3 123.6 151.2 118.9 225.4 121.9 82.7 112.3 149.1 127.1 91.2 168.2 146.0 140.5 345.1 43.5 127.7 80.0 74.5 162.0 265.3 34.4 0.6 2.9 0.6 0.1 0.4 1.1 1.3 1.3 2.4 0.5 1.2 0.4 0.4 3.0 0.3 2.6 8.0 1.0 6.4 6.1 10.3 8.4 5.6 4.9 4.8 5.2 5.2 4.9 4.2 5.6 2.5 0.0 3.1 1.3 6.8 16.6 6.6 8.0 2.2 6.4 3.4 4.3 3.2 0.0 7.6 3.7 0.0 45.5 2.8 16.5 0.0 3.2 41.5 4.5 4.0 4.7 5.4 142.9 5.0 2.9 68.3 7.2 16.3 6.8 8.9 13.2 9.3 2.1 21.5 3.3 5.2 17.0 10.2 8.7 15.0 15.4 3.7 5.2 3.6 1.9 5.5 3.8 4.1 2.0 1.7 2.3 3.2 1.9 17.5 5.9 2.0 0.1 3.2 4.6 6.6 7.4 10.9 136.4 74.2 38.0 14.2 14.6 6.8 0.4 24.1 6.7 PRDM6 "KMT8C, PRISM" ENSG00000061455 "PR/SET domain 6" Q9NQX0 5 123089241-123194266 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 4.9;urinary bladder: 9.0" "Cell type enhanced" "Detected in some" "Astrocytes: 15.0;Endometrial stromal cells: 6.5;Excitatory neurons: 7.9;Fibroblasts: 10.7;Late spermatids: 7.1;Oligodendrocytes: 11.0" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 3.6;HEK 293: 5.2;HEL: 1.1" "Not detected" "Not detected" "Region enhanced" "Detected in single" "spinal cord: 2.3" HPA030324 Uncertain Approved Nucleoplasm NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 28: BEWO - Transcription regulation" "Cluster 33: Fibroblasts - ECM organization" Nucleoplasm "HPA030324: AB_10670032" "unprognostic (2.33e-1)" "unprognostic (1.39e-1)" "unprognostic (2.18e-1)" "unprognostic (2.32e-3)" "unprognostic (3.12e-1)" "unprognostic (5.44e-2)" "unprognostic (2.22e-1)" "unprognostic (1.54e-2)" "unprognostic (4.66e-2)" "unprognostic (7.66e-3)" "unprognostic (1.23e-1)" "unprognostic (1.92e-2)" "unprognostic (1.02e-7)" "unprognostic (9.30e-4)" "unprognostic (1.10e-1)" "unprognostic (3.43e-4)" "unprognostic (1.27e-1)" 0.7 0.1 0.2 0.3 0.2 0.0 0.6 0.2 0.3 0.9 0.6 4.9 0.2 0.7 0.1 0.6 0.4 3.3 0.5 0.1 0.2 0.3 0.1 2.9 0.0 0.3 0.4 1.9 0.3 0.1 0.3 4.2 0.4 1.3 1.0 0.2 0.1 0.1 0.1 0.2 0.6 0.7 0.3 0.0 0.6 0.3 0.2 0.0 0.8 0.2 0.2 9.0 0.6 0.3 0.0 0.0 0.0 0.3 0.3 0.4 3.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.7 0.0 0.0 0.1 5.2 1.1 0.5 0.0 1.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.6 0.2 0.0 0.8 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.3 0.1 0.2 0.3 0.4 0.4 0.3 0.2 0.3 0.5 0.0 0.0 15.0 0.0 1.9 0.1 0.0 0.0 1.0 0.6 0.3 1.4 0.0 0.0 0.0 2.1 0.3 0.0 0.0 0.0 0.1 3.3 0.6 6.5 0.5 0.0 0.0 7.9 0.2 0.3 10.7 0.0 0.5 0.0 2.4 0.0 0.5 0.8 0.0 6.4 0.1 0.0 0.8 3.5 7.1 2.1 0.4 3.6 4.7 0.8 0.2 0.0 3.0 11.0 0.1 0.0 1.2 0.1 0.2 0.0 0.8 0.2 1.0 0.0 0.7 2.2 2.3 4.4 0.2 1.3 0.4 0.4 6.1 0.0 0.1 PREP ENSG00000085377 "Prolyl endopeptidase" P48147 6 105273218-105454062 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 84.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 79.7;Syncytiotrophoblasts: 67.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025414, HPA031388, HPA031389, HPA031390" Supported Supported Cytosol NA NA 1700000 "Cluster 27: Non-specific - Gene expression" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 30: Epithelial cell lines - Translation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "CAB025414: , HPA031388: AB_2673855, HPA031389: AB_2673856, HPA031390: AB_2673857" "unprognostic (3.05e-2)" "unprognostic (9.09e-3)" "unprognostic (2.85e-2)" "unprognostic (5.46e-2)" "unprognostic (3.36e-1)" "prognostic unfavorable (3.33e-4)" "unprognostic (2.63e-3)" "unprognostic (2.39e-1)" "unprognostic (6.78e-2)" "unprognostic (5.81e-2)" "unprognostic (2.66e-2)" "unprognostic (1.15e-1)" "unprognostic (4.47e-3)" "unprognostic (2.74e-2)" "unprognostic (8.98e-2)" "unprognostic (6.59e-2)" "unprognostic (2.33e-1)" 17.3 17.4 7.2 14.6 8.1 14.3 17.7 7.4 12.0 15.2 7.8 32.1 23.6 15.8 12.1 21.1 13.0 8.7 22.5 8.8 7.3 11.3 19.0 16.2 13.6 6.7 7.7 16.0 19.2 20.5 13.0 17.8 6.8 11.6 37.5 15.4 18.6 9.0 84.8 33.4 25.6 15.3 6.6 14.3 18.7 21.4 8.8 16.4 12.3 46.9 16.2 21.4 17.5 8.5 22.3 26.9 27.9 32.1 63.1 37.1 27.7 28.6 27.0 37.2 39.0 35.9 14.2 28.5 26.8 33.9 35.0 33.3 41.8 86.5 42.7 41.8 37.4 38.1 21.7 40.0 25.3 40.5 26.2 35.8 53.4 27.6 71.7 28.0 35.4 50.1 67.4 49.8 45.5 38.8 25.8 41.4 27.9 44.2 25.0 41.1 48.4 18.3 28.2 53.8 36.0 51.8 25.3 42.0 21.7 35.3 17.9 61.9 36.1 17.3 23.9 21.6 36.2 14.2 9.7 38.5 30.4 42.6 56.6 5.5 15.2 8.4 16.3 16.8 16.8 9.3 14.2 17.1 16.5 6.9 12.9 15.5 0.8 19.9 22.7 7.0 13.6 13.5 7.2 8.1 7.4 12.0 8.8 7.3 6.7 7.7 6.8 6.6 8.8 8.5 6.3 3.2 6.7 22.9 10.1 10.8 6.8 12.0 5.7 5.1 6.0 5.5 14.8 7.2 13.6 7.3 14.6 28.2 14.5 19.3 5.9 10.4 1.4 6.6 15.1 10.1 19.3 11.2 79.7 11.7 35.9 10.6 24.5 11.6 13.4 11.2 7.5 15.1 15.0 13.5 48.3 29.4 10.2 14.2 10.8 3.2 10.8 13.3 5.4 27.2 19.1 3.3 5.2 28.6 18.7 18.0 29.1 9.1 11.0 5.3 18.5 8.8 4.8 10.4 0.0 8.3 10.3 3.9 18.8 12.9 8.5 67.9 16.1 14.4 38.2 8.5 PREX1 "KIAA1415, P-REX1" ENSG00000124126 "Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1" Q8TCU6 20 48624252-48827999 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 52.5;brain: 78.1" "Cell type enhanced" "Detected in many" "Astrocytes: 87.1;dendritic cells: 84.0;Kupffer cells: 104.7;Macrophages: 76.5;Microglial cells: 95.5;NK-cells: 90.6;Oligodendrocytes: 190.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MCF7: 157.9;SK-BR-3: 162.2;T-47d: 145.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001927 Supported Supported Vesicles,Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 41: Macrophages - Immune response" "Vesicles, Cytosol" "HPA001927: AB_1079674" "unprognostic (8.07e-2)" "unprognostic (3.16e-2)" "unprognostic (2.15e-2)" "unprognostic (2.55e-1)" "unprognostic (7.47e-2)" "prognostic favorable (8.56e-4)" "unprognostic (2.16e-1)" "unprognostic (1.85e-1)" "unprognostic (1.31e-1)" "unprognostic (5.21e-2)" "unprognostic (1.13e-2)" "unprognostic (2.70e-2)" "unprognostic (5.86e-3)" "unprognostic (6.84e-2)" "unprognostic (2.31e-1)" "unprognostic (1.50e-1)" "unprognostic (1.01e-2)" 14.8 10.6 32.8 37.4 56.4 52.5 15.0 43.2 47.2 12.3 1.2 7.0 6.3 4.0 1.4 6.4 4.7 13.0 6.7 32.1 42.0 4.8 5.2 26.8 36.6 52.1 52.0 2.5 5.3 6.9 7.6 11.7 53.8 4.8 6.0 3.9 5.3 3.4 6.6 3.5 12.7 7.7 43.5 42.9 8.8 6.0 45.3 9.8 9.4 8.6 21.8 12.3 3.2 78.1 2.3 6.1 78.4 0.0 1.3 5.7 27.2 2.7 3.5 11.2 2.8 0.4 0.3 16.4 49.5 7.2 21.4 1.0 4.1 0.2 7.5 3.7 2.0 2.4 8.8 0.0 4.6 9.0 51.1 6.3 0.0 25.7 0.0 7.6 68.4 7.2 0.2 0.6 14.8 157.9 0.2 24.7 3.1 8.1 6.4 24.1 22.8 9.8 0.5 0.0 16.5 2.4 14.7 162.2 17.8 4.4 145.0 67.4 77.2 4.5 15.6 0.2 4.6 0.9 3.5 20.1 72.4 17.8 24.3 4.5 1.9 2.2 3.7 2.2 2.2 1.5 2.0 3.2 1.6 1.4 0.3 1.1 9.2 1.8 2.0 1.3 7.3 2.0 32.8 56.4 43.2 47.2 32.1 42.0 52.1 52.0 53.8 43.5 45.3 78.1 43.2 3.2 6.6 87.1 35.4 2.5 0.3 0.4 1.2 0.3 40.0 21.5 3.7 2.8 2.6 1.8 8.4 0.7 84.0 0.9 0.0 0.2 3.5 3.5 4.7 24.5 1.2 14.1 13.3 1.2 4.4 10.3 4.1 6.2 1.3 0.7 20.7 1.9 32.1 0.0 4.6 1.8 0.0 104.7 28.2 2.9 0.9 76.5 8.8 95.5 47.1 19.4 90.6 49.3 190.2 0.1 1.0 0.4 23.3 0.7 0.3 0.2 4.5 0.7 0.0 18.1 3.3 2.2 11.6 0.4 2.4 9.3 63.9 41.2 4.5 0.7 PRIM1 ENSG00000198056 "DNA primase subunit 1" P49642 12 56731296-56752374 "Predicted intracellular proteins" "DNA replication, Transcription" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 28.2" "Cell type enhanced" "Detected in many" "Erythroid cells: 56.4;Spermatocytes: 118.2;Spermatogonia: 107.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040010 Uncertain NA Yes "Cluster 24: B-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA040010: AB_10805599" "unprognostic (3.04e-3)" "unprognostic (1.67e-2)" "unprognostic (2.12e-2)" "unprognostic (1.51e-2)" "unprognostic (4.63e-2)" "unprognostic (3.61e-2)" "prognostic unfavorable (2.40e-8)" "unprognostic (4.68e-2)" "unprognostic (2.73e-3)" "unprognostic (1.82e-3)" "unprognostic (1.56e-1)" "unprognostic (1.82e-1)" "unprognostic (1.98e-3)" "unprognostic (3.94e-1)" "unprognostic (2.16e-1)" "unprognostic (5.35e-2)" "unprognostic (6.53e-2)" 3.7 3.2 2.0 7.0 2.8 28.2 9.9 5.5 2.8 3.7 1.2 7.9 4.5 5.0 4.2 4.4 5.3 2.9 2.3 1.9 2.0 3.0 7.5 4.9 12.3 2.5 2.2 8.9 6.1 6.1 2.1 4.8 2.6 3.6 11.2 8.3 3.9 3.9 4.6 7.8 7.7 5.8 2.0 6.9 5.4 14.4 2.3 18.8 5.0 5.6 14.4 3.8 3.1 4.3 43.0 37.9 52.1 29.2 5.1 9.1 57.8 34.7 28.7 62.1 59.8 42.0 54.4 83.0 27.4 15.8 26.0 40.4 60.3 39.9 68.8 40.7 40.4 106.2 22.6 36.8 1.2 129.3 43.2 4.2 7.2 55.8 22.1 8.8 22.6 92.1 105.5 123.8 35.4 33.6 76.8 54.4 53.5 32.0 47.1 85.0 81.4 70.9 15.0 35.4 51.0 46.0 41.4 20.6 19.9 36.2 67.2 52.8 10.9 32.2 70.7 33.1 46.4 45.1 94.5 45.3 19.4 55.4 40.9 2.5 1.9 4.4 9.1 4.0 9.5 11.3 11.2 8.5 3.9 12.2 14.0 10.7 1.0 6.8 7.1 7.5 10.0 5.3 2.0 2.8 5.5 2.8 1.9 2.0 2.5 2.2 2.6 2.0 2.3 4.3 6.9 6.4 6.8 4.6 10.4 3.8 10.7 10.0 4.6 5.1 7.0 7.2 3.2 2.8 6.1 7.3 6.2 14.9 8.7 2.5 0.0 5.8 6.2 4.1 3.9 6.4 1.2 56.4 5.7 7.2 27.0 5.4 5.6 3.3 3.8 10.0 5.7 4.7 11.8 20.2 10.6 4.6 2.0 8.1 3.1 4.3 7.2 6.5 3.6 2.8 7.9 5.7 8.2 8.0 7.8 2.7 2.2 4.9 9.7 2.2 2.0 2.5 6.0 12.7 13.1 8.2 8.8 118.2 107.2 5.1 4.0 4.5 12.8 3.0 9.4 5.0 PRKAA1 AMPKa1 ENSG00000132356 "Protein kinase AMP-activated catalytic subunit alpha 1" Q13131 5 40759379-40798374 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Autophagy, Biological rhythms, Cholesterol biosynthesis, Cholesterol metabolism, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism, Transcription, Transcription regulation, Wnt signaling pathway" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 292.5;Late spermatids: 478.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005050, HPA035409, HPA064946" Supported Supported "Nuclear speckles,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 31: Spermatids - Spermatogenesis" "Nuclear speckles" Cytosol "CAB005050: AB_562037, HPA035409: AB_2674613, HPA064946: AB_2685390" "unprognostic (2.07e-1)" "unprognostic (1.41e-2)" "unprognostic (2.51e-2)" "unprognostic (3.57e-2)" "unprognostic (3.97e-1)" "unprognostic (1.05e-1)" "unprognostic (3.51e-2)" "unprognostic (7.53e-2)" "unprognostic (1.66e-2)" "unprognostic (2.88e-1)" "unprognostic (3.34e-3)" "unprognostic (2.63e-1)" "unprognostic (2.82e-2)" "unprognostic (1.35e-1)" "unprognostic (1.60e-1)" "unprognostic (1.27e-2)" "unprognostic (1.10e-2)" 33.3 21.0 7.9 27.2 9.6 52.6 30.2 10.3 11.0 26.7 12.3 30.0 35.4 26.3 18.6 20.6 21.0 33.5 20.2 6.9 11.3 32.0 49.9 27.4 29.2 11.8 9.9 19.1 23.1 32.0 9.2 21.2 12.2 31.9 34.7 19.0 27.4 24.7 16.9 23.1 30.9 26.4 10.2 27.8 33.7 41.1 10.0 21.8 32.3 19.9 23.9 28.8 17.8 10.3 28.4 28.9 22.8 30.2 55.0 57.0 21.6 47.3 48.1 34.7 30.8 27.6 35.9 16.6 21.4 48.8 45.3 22.4 21.3 43.1 64.9 49.2 19.2 33.1 66.1 22.1 45.3 31.9 33.5 52.8 20.6 46.5 47.5 38.4 52.1 21.0 15.9 46.7 52.4 13.6 29.7 24.9 9.9 28.9 34.6 24.5 48.7 24.6 53.3 47.5 19.6 19.7 83.0 54.3 28.8 12.3 28.4 26.0 56.0 62.1 33.5 36.2 39.2 18.5 15.4 19.6 38.9 67.9 33.9 17.0 6.5 12.8 8.9 7.9 11.5 8.2 8.4 8.6 6.4 7.9 10.1 9.0 15.4 10.9 9.3 1.9 11.6 6.5 7.9 9.6 10.3 11.0 6.9 11.3 11.8 9.9 12.2 10.2 10.0 10.3 47.3 41.7 26.5 19.2 34.1 24.1 24.7 40.5 15.4 20.3 36.1 17.9 18.3 42.9 43.4 47.8 35.5 13.8 45.8 44.1 7.9 27.9 292.5 19.7 35.8 42.4 21.1 25.4 24.5 44.9 13.7 36.2 36.7 20.7 18.3 17.8 37.1 83.4 20.0 15.2 30.3 28.8 42.7 25.3 28.5 478.5 30.4 24.1 35.6 24.4 40.9 15.4 44.3 30.7 43.8 36.0 32.8 25.9 23.4 33.4 33.7 35.4 42.9 27.9 0.0 22.7 43.1 82.8 17.6 19.9 32.7 18.6 44.0 19.2 36.9 35.0 PRKAG2 "AAKG, AAKG2, CMH6, H91620p, WPWS" ENSG00000106617 "Protein kinase AMP-activated non-catalytic subunit gamma 2" Q9UGJ0 7 151556124-151877125 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "Cardiomyopathy, Disease variant, FDA approved drug targets, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 143.0" "Cell type enhanced" "Detected in all" "Excitatory neurons: 208.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "GAMG: 178.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004246, CAB018641" Uncertain Approved Nucleoplasm NA NA "Cluster 34: Basophils - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "CAB018641: AB_2170355, HPA004246: AB_1078151" "unprognostic (4.11e-2)" "unprognostic (2.82e-1)" "unprognostic (1.46e-2)" "unprognostic (9.29e-2)" "unprognostic (1.76e-1)" "unprognostic (4.33e-3)" "unprognostic (7.13e-2)" "unprognostic (8.09e-2)" "unprognostic (1.77e-1)" "unprognostic (1.18e-1)" "unprognostic (2.46e-2)" "unprognostic (1.42e-1)" "unprognostic (1.35e-1)" "unprognostic (1.67e-1)" "unprognostic (3.80e-1)" "unprognostic (3.61e-2)" "unprognostic (4.52e-1)" 27.1 7.7 21.7 12.8 20.3 8.1 18.4 16.7 22.8 16.2 11.1 25.8 24.4 19.8 14.3 16.2 17.9 12.8 143.0 23.7 21.1 22.5 36.1 14.2 11.6 19.3 17.4 10.9 10.9 9.2 9.5 16.1 19.7 25.3 18.9 2.9 15.0 19.5 15.0 13.5 26.2 16.5 15.8 17.6 26.7 12.8 18.5 7.9 16.6 21.7 9.8 47.9 17.5 19.6 46.6 13.6 9.1 10.6 36.4 28.6 14.4 21.5 19.5 22.7 22.3 8.6 52.5 0.0 34.0 28.9 178.2 13.9 5.7 22.4 30.0 15.8 6.2 11.5 1.8 0.9 60.8 8.5 11.4 16.5 49.7 21.8 21.0 34.1 40.2 14.9 4.1 5.6 66.2 17.2 3.5 6.7 9.7 18.8 37.5 5.6 6.9 9.7 39.2 10.9 38.5 6.7 10.7 19.9 10.0 22.9 4.0 13.6 52.8 5.0 4.3 2.8 13.1 3.5 5.1 0.0 63.5 29.8 45.9 26.2 9.3 10.9 5.3 7.0 4.1 9.6 4.9 4.8 6.5 4.0 4.8 7.3 11.1 4.4 6.4 6.0 2.9 5.3 21.7 20.3 16.7 22.8 23.7 21.1 19.3 17.4 19.7 15.8 18.5 19.6 19.2 6.4 19.8 37.5 24.8 10.6 39.9 25.0 19.9 22.3 20.6 14.5 122.3 8.6 22.9 46.0 8.4 3.9 43.8 29.5 64.6 14.1 49.3 75.1 16.9 20.4 13.1 3.8 208.5 22.7 31.2 24.9 21.9 98.1 22.2 4.6 18.9 76.8 17.7 3.3 85.2 34.5 105.8 57.2 48.2 35.8 7.5 50.9 16.0 73.1 62.9 14.7 37.0 39.2 4.4 27.5 21.9 7.9 23.4 45.7 77.7 19.7 14.2 6.1 13.1 6.9 27.3 4.0 32.3 12.8 10.9 50.6 27.3 5.0 28.0 45.2 PRKCB "PKCβ, PKCB, PRKCB1, PRKCB2" ENSG00000166501 "Protein kinase C beta" P05771 16 23835983-24220611 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins, Transporters" "Adaptive immunity, Apoptosis, Immunity, Transcription, Transcription regulation" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 84.0;lymphoid tissue: 47.2" "Cell type enhanced" "Detected in many" "B-cells: 185.1;Bipolar cells: 208.6;Excitatory neurons: 877.7;Inhibitory neurons: 320.2;Kupffer cells: 221.9" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 95 "amygdala: 28.9;basal ganglia: 53.9;cerebral cortex: 84.0;hippocampal formation: 35.3;white matter: 36.6" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 161.8;HMC-1: 154.8;K-562: 234.9;THP-1: 72.7;U-937: 64.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003843, HPA048321, HPA054203" Approved Supported Nucleoplasm,Cytosol NA NA 380000 "Cluster 6: Non-specific - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 1: K-562 - Erythropoiesis" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm Cytosol "CAB003843: AB_562197, HPA048321: AB_2680357, HPA054203: AB_2682416" "unprognostic (1.53e-3)" "unprognostic (4.53e-4)" "unprognostic (2.52e-3)" "unprognostic (3.07e-2)" "unprognostic (1.72e-1)" "unprognostic (7.13e-3)" "unprognostic (2.06e-1)" "unprognostic (1.67e-3)" "unprognostic (3.19e-2)" "unprognostic (1.79e-1)" "unprognostic (7.38e-2)" "unprognostic (1.06e-1)" "unprognostic (3.17e-3)" "unprognostic (2.08e-1)" "unprognostic (2.12e-2)" "unprognostic (3.28e-1)" "unprognostic (4.95e-2)" 4.4 1.6 28.9 30.8 53.9 32.1 1.5 0.5 84.0 4.2 0.0 9.7 5.9 3.8 0.6 3.5 3.8 4.4 1.1 35.3 0.0 2.8 4.2 7.8 47.1 0.0 0.0 0.6 1.0 0.2 1.4 2.7 0.0 7.3 5.1 18.2 1.5 10.2 0.8 5.5 19.4 7.2 0.0 46.2 5.7 8.4 0.0 47.2 4.5 1.0 40.0 8.7 1.7 36.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.5 1.0 0.0 0.3 0.5 0.5 0.0 0.0 0.0 3.2 161.8 7.5 0.0 0.0 23.6 154.8 0.0 0.7 0.0 0.0 0.0 0.0 27.3 234.9 0.6 0.0 0.0 52.1 51.4 1.5 0.0 0.0 49.0 0.4 9.5 0.5 14.1 27.2 0.0 0.2 0.2 2.4 0.8 0.0 72.7 1.1 0.0 0.3 0.1 0.0 4.1 0.0 1.4 0.2 64.4 0.3 39.3 13.3 27.8 24.8 20.0 11.5 44.2 15.9 29.9 11.3 40.0 13.0 32.0 39.1 39.9 28.6 33.8 12.7 15.5 28.9 53.9 0.5 84.0 35.3 0.0 0.0 0.0 0.0 0.0 0.0 36.6 1.1 3.2 4.9 21.5 185.1 6.0 4.1 0.1 0.6 208.6 0.9 0.8 2.0 2.8 1.8 1.8 2.1 0.2 166.3 1.4 0.0 0.0 26.5 0.1 0.1 4.1 0.0 26.3 877.7 0.2 0.3 1.7 1.5 0.1 71.5 1.9 11.4 3.1 50.5 79.1 320.2 1.5 0.0 221.9 20.5 11.7 0.0 100.9 3.6 110.5 154.4 10.8 120.5 102.1 132.5 0.0 9.6 0.4 61.8 1.0 6.7 0.8 1.6 9.9 0.0 4.4 1.6 3.4 3.6 0.5 14.3 0.8 68.1 0.2 3.8 4.5 PRKCE ENSG00000171132 "Protein kinase C epsilon" Q02156 2 45651345-46187990 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Cell adhesion, Cell cycle, Cell division, Immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 34.5" "Cell type enhanced" "Detected in many" "Early spermatids: 206.5;Excitatory neurons: 394.4;Inhibitory neurons: 531.9;Late spermatids: 456.4;Oligodendrocyte precursor cells: 147.8" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 4 "amygdala: 18.5;basal ganglia: 20.0;cerebral cortex: 34.5;hippocampal formation: 33.1;white matter: 17.1" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "REH: 27.0;TIME: 26.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001948, HPA008236, HPA044496" Enhanced Supported Supported "Vesicles,Plasma membrane,Intermediate filaments,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 58: Brain - Synaptic function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Intermediate filaments, Cytosol" "Vesicles, Plasma membrane" "CAB001948: , HPA008236: , HPA044496: AB_2678959" "unprognostic (1.10e-1)" "unprognostic (1.78e-1)" "unprognostic (2.27e-1)" "prognostic unfavorable (2.42e-4)" "unprognostic (9.61e-2)" "unprognostic (5.70e-2)" "unprognostic (1.51e-1)" "prognostic favorable (9.62e-4)" "unprognostic (3.05e-1)" "unprognostic (6.72e-2)" "unprognostic (7.49e-3)" "unprognostic (9.99e-2)" "prognostic favorable (2.63e-7)" "unprognostic (1.21e-1)" "unprognostic (7.11e-2)" "unprognostic (6.43e-3)" "unprognostic (2.23e-2)" 4.4 5.6 18.5 3.7 20.0 8.0 4.2 5.5 34.5 4.6 0.0 5.7 2.6 4.4 2.3 4.1 5.7 3.0 6.2 33.1 0.0 10.0 12.5 20.1 5.7 6.0 0.2 2.8 3.3 9.4 5.2 8.3 4.4 2.9 3.3 15.4 2.7 3.0 7.6 2.7 3.5 4.1 0.0 3.9 4.1 7.6 1.1 3.1 4.9 5.3 4.2 4.9 3.4 17.1 7.7 2.7 3.8 3.8 5.8 6.7 3.1 4.9 9.5 4.3 4.5 0.7 7.0 11.3 4.8 5.5 6.1 1.8 2.5 2.8 6.1 6.9 4.4 0.1 1.8 1.5 6.5 0.9 3.8 5.8 3.0 6.5 4.7 3.6 16.0 2.4 1.6 2.6 5.0 3.8 3.8 0.5 1.3 4.2 1.4 27.0 18.3 12.4 3.9 5.1 2.6 5.7 2.4 7.6 17.1 1.4 6.1 2.6 26.8 8.2 8.5 6.1 5.1 0.0 0.0 9.3 6.7 6.3 8.4 0.0 0.5 0.7 0.3 0.1 0.4 1.5 0.2 0.2 0.8 1.8 0.5 0.1 0.1 0.4 0.6 0.3 0.0 0.3 18.5 20.0 5.5 34.5 33.1 0.0 6.0 0.2 4.4 0.0 1.1 17.1 12.6 6.4 9.2 90.4 20.7 5.0 8.4 5.0 9.1 55.3 6.4 5.7 11.9 8.6 17.2 11.0 14.6 0.5 9.3 6.1 3.9 3.7 206.5 6.8 7.0 13.8 7.7 0.4 394.4 3.8 7.2 8.7 11.2 6.9 7.0 2.9 13.2 12.5 2.8 11.8 531.9 5.8 0.0 19.0 10.7 456.4 5.3 11.5 14.2 70.3 9.4 6.5 1.0 147.8 96.0 3.6 2.9 6.0 4.2 5.3 4.1 30.2 19.3 7.6 13.1 2.9 6.4 2.8 2.3 9.0 4.8 2.9 6.8 1.2 6.2 8.8 PRKCZ PKC2 ENSG00000067606 "Protein kinase C zeta" Q05513 1 2050411-2185395 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Inflammatory response" "Kinase, Serine/threonine-protein kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 58.0" "Group enriched" "Detected in many" 4 "Late spermatids: 708.3;Syncytiotrophoblasts: 1107.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "eosinophil: 16.3" "Lineage enriched" "Detected in many" 6 "granulocytes: 16.3" "Cell line enhanced" "Detected in many" "BEWO: 44.5;OE19: 41.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021851 Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 6: Brain - Smell perception" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "Plasma membrane" "HPA021851: AB_1855433" "unprognostic (1.25e-2)" "unprognostic (2.61e-1)" "unprognostic (5.10e-2)" "unprognostic (1.14e-2)" "unprognostic (2.08e-1)" "unprognostic (3.61e-2)" "unprognostic (1.73e-2)" "unprognostic (5.13e-2)" "unprognostic (1.18e-1)" "unprognostic (3.10e-1)" "unprognostic (1.12e-1)" "unprognostic (2.86e-1)" "prognostic favorable (1.64e-9)" "unprognostic (3.57e-2)" "unprognostic (3.27e-2)" "unprognostic (1.39e-1)" "unprognostic (7.85e-2)" 1.7 11.1 23.6 4.6 25.7 2.1 5.6 58.0 41.3 4.3 0.0 13.2 29.3 2.2 7.8 16.0 9.5 4.4 9.7 23.7 10.2 16.0 11.0 31.6 8.0 18.6 8.3 2.7 12.5 14.7 17.6 43.8 19.0 8.4 11.3 14.8 10.8 3.9 0.3 13.8 28.0 1.6 5.6 10.5 8.9 31.9 7.2 3.7 21.8 0.6 7.8 5.8 8.0 24.8 14.7 9.7 3.4 17.2 0.0 0.0 44.5 1.2 0.5 11.1 0.7 23.8 31.0 0.1 27.4 3.9 9.4 25.4 20.5 25.5 7.9 1.0 21.8 0.0 15.2 33.5 3.2 0.1 11.0 0.6 14.9 0.0 8.6 0.0 0.0 4.0 6.6 0.2 0.2 17.9 0.9 0.0 6.4 41.9 22.5 0.0 0.0 5.1 18.6 16.0 24.1 18.7 11.6 27.5 5.2 28.7 17.7 4.0 0.0 0.1 13.1 0.1 0.1 6.8 1.3 0.3 1.2 0.3 16.8 0.3 0.0 16.3 0.5 0.3 2.5 0.3 0.9 0.6 0.0 0.4 0.8 0.3 1.1 0.9 0.0 0.3 0.9 0.3 23.6 25.7 58.0 41.3 23.7 10.2 18.6 8.3 19.0 5.6 7.2 24.8 0.9 121.8 72.2 2.3 6.5 13.0 11.8 11.0 10.2 27.1 11.3 11.0 1.4 5.7 21.1 7.3 4.2 118.7 7.5 48.9 7.9 12.3 224.4 14.0 4.7 6.3 10.2 6.6 39.5 10.7 66.3 3.1 17.9 11.7 8.2 12.5 10.0 16.5 14.5 62.2 35.2 25.5 10.2 0.8 2.9 708.3 9.6 4.4 7.2 2.8 4.5 19.1 8.2 13.0 41.3 14.2 45.7 8.6 7.4 19.5 78.4 24.7 22.1 25.9 0.0 0.3 4.1 28.3 28.4 13.4 13.4 1107.9 9.8 2.6 31.3 14.3 PROK2 "BV8, KAL4, MIT1, PK2" ENSG00000163421 "Prokineticin 2" Q9HC23 3 71771655-71785206 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Biological rhythms" Neuropeptide "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 64.5;lymphoid tissue: 22.5" "Cell type enhanced" "Detected in some" "Erythroid cells: 5.9;Kupffer cells: 8.0;Macrophages: 11.3;monocytes: 6.9;Spermatocytes: 23.8" "Cancer enhanced" "Detected in some" "ovarian cancer: 2.1" "Region enriched" "Detected in many" 7 "cerebral cortex: 13.3" "Immune cell enriched" "Detected in many" 50 "neutrophil: 414.4" "Lineage enriched" "Detected in many" 50 "granulocytes: 414.4" "Cell line enhanced" "Detected in some" "HL-60: 9.2;NB-4: 8.9;NTERA-2: 5.5;U-266/70: 12.0;U-266/84: 20.8;U-937: 8.3" "Group enriched" "Detected in some" 6 "basal ganglia: 2.7;hypothalamus: 1.1;olfactory bulb: 3.5" "Low region specificity" "Detected in all" HPA041408 Approved "Secreted to blood" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 16: U-266 - Nucleosome" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA041408: AB_10964057" "unprognostic (5.24e-2)" "unprognostic (3.13e-3)" "unprognostic (3.51e-3)" "unprognostic (3.59e-2)" "unprognostic (1.89e-1)" "unprognostic (2.94e-1)" "unprognostic (2.97e-2)" "unprognostic (9.52e-2)" "unprognostic (4.29e-2)" "unprognostic (9.91e-3)" "unprognostic (6.89e-2)" "unprognostic (5.73e-1)" "unprognostic (1.59e-4)" "unprognostic (2.02e-2)" "unprognostic (1.48e-1)" "unprognostic (1.40e-2)" "unprognostic (2.16e-2)" 7.2 0.3 0.7 17.7 0.5 64.5 0.3 0.1 13.3 0.4 0.7 0.4 0.3 0.2 0.0 0.4 2.7 1.2 1.0 0.2 0.5 0.6 2.5 13.1 0.2 0.5 1.0 0.2 1.1 0.0 0.4 3.1 1.2 0.2 0.2 0.1 0.3 0.0 0.5 0.1 0.5 1.5 0.2 22.5 0.6 11.4 1.9 1.1 0.5 4.2 0.5 6.0 0.4 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 9.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 3.3 1.6 0.0 0.0 0.0 0.3 8.9 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 20.8 0.0 0.0 8.3 0.0 0.0 8.2 3.5 3.4 0.7 0.0 0.0 2.7 2.9 0.7 0.0 0.9 5.0 414.4 0.0 0.2 0.3 1.7 3.1 0.7 0.5 0.1 13.3 0.2 0.5 0.5 1.0 1.2 0.2 1.9 0.7 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.6 1.8 0.0 0.0 2.5 0.0 0.0 0.0 1.6 0.1 0.1 0.1 0.0 5.9 0.0 0.0 0.0 0.9 0.0 0.0 1.3 0.0 0.0 0.0 0.5 0.0 0.4 0.0 0.0 8.0 0.3 2.8 0.3 11.3 1.8 0.0 6.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.1 23.8 2.9 0.0 0.0 0.0 3.5 0.1 0.0 0.0 PRR13 "DKFZP564J157, FLJ23818" ENSG00000205352 "Proline rich 13" Q9NZ81 12 53441678-53446645 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 884.9;Distal tubular cells: 1365.6;Paneth cells: 858.1;Proximal enterocytes: 1642.7;Proximal tubular cells: 1097.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039396, HPA046219" Uncertain Supported Nucleoplasm NA Yes "Cluster 8: Neutrophils - Inflammatory response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" Nucleoplasm "HPA039396: AB_2676484, HPA046219: AB_10963936" "unprognostic (1.09e-1)" "prognostic favorable (9.08e-4)" "unprognostic (1.15e-1)" "unprognostic (3.26e-1)" "unprognostic (8.97e-3)" "unprognostic (4.88e-3)" "unprognostic (1.86e-3)" "unprognostic (7.23e-2)" "unprognostic (1.23e-1)" "unprognostic (3.49e-1)" "unprognostic (1.41e-2)" "unprognostic (5.41e-2)" "unprognostic (6.81e-3)" "unprognostic (1.81e-1)" "unprognostic (1.08e-1)" "unprognostic (2.34e-1)" "prognostic favorable (7.55e-4)" 143.8 207.8 110.8 159.2 110.1 279.1 139.2 112.6 147.7 118.9 109.7 316.1 451.6 104.6 110.8 143.4 139.2 147.1 110.6 105.8 147.8 457.9 192.8 164.3 185.3 126.6 132.1 118.8 133.3 76.0 114.6 95.2 126.3 139.6 265.7 44.0 115.5 86.6 131.6 108.7 432.6 91.4 114.3 230.2 247.8 46.4 118.4 139.0 131.8 59.6 190.4 143.7 111.7 117.1 171.7 339.6 82.6 89.4 135.3 185.3 178.4 142.5 213.0 185.6 179.4 623.1 373.6 265.1 453.5 206.8 225.4 146.6 167.8 225.0 217.9 263.1 124.6 382.4 166.4 294.6 340.7 573.2 489.5 232.6 221.2 326.5 223.6 192.6 195.3 166.1 340.1 254.6 285.1 472.5 325.8 563.8 127.5 229.2 230.7 287.6 67.8 273.9 406.2 283.8 72.3 56.5 202.5 276.7 237.2 169.5 394.0 436.2 196.3 117.2 114.0 201.3 138.0 190.7 241.6 386.4 153.3 345.1 220.2 851.3 824.0 1620.1 511.1 941.9 503.0 888.2 563.7 545.8 649.3 855.6 520.6 557.7 2095.7 584.5 1014.6 539.0 824.8 1573.1 110.8 110.1 112.6 147.7 105.8 147.8 126.6 132.1 126.3 114.3 118.4 117.1 66.8 83.3 110.4 6.8 219.1 47.5 147.8 204.8 82.6 11.1 114.3 95.2 26.4 198.8 145.1 187.6 29.2 225.3 159.1 884.9 1365.6 228.0 12.6 182.7 67.1 80.3 169.8 99.2 6.3 253.9 337.7 76.6 263.0 127.4 186.7 53.4 78.1 152.8 355.2 18.5 7.1 346.9 193.3 345.0 174.4 8.7 58.1 266.8 108.5 9.4 384.7 85.3 297.6 4.5 12.9 332.3 858.1 45.9 120.9 174.7 1642.7 1097.6 215.9 20.9 78.9 33.6 67.1 29.7 22.8 107.1 56.0 291.0 212.7 88.4 340.0 193.1 PRR30 "C2orf53, MGC44505" ENSG00000186143 "Proline rich 30" Q53SZ7 2 27136848-27139410 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1006 "testis: 147.6" "Group enriched" "Detected in some" 48 "Early spermatids: 646.9;Late spermatids: 773.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (5.60e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 147.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 646.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 773.6 5.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRSS3 "PRSS4, TRY3, TRY4" ENSG00000010438 "Serine protease 3" P35030 9 33750679-33799231 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 268 "pancreas: 31113.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 1022.9;Exocrine glandular cells: 2040.4;Pancreatic endocrine cells: 478.8;Paneth cells: 969.9;Proximal enterocytes: 1127.1" "Group enriched" "Detected in many" 7 "colorectal cancer: 72.8;pancreatic cancer: 104.4;stomach cancer: 43.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 104 "basophil: 158.7" "Lineage enriched" "Detected in many" 104 "granulocytes: 158.7" "Group enriched" "Detected in many" 5 "OE19: 316.6;PC-3: 852.5" "HPA062452, HPA063471" Supported Approved "Endoplasmic reticulum,Vesicles" "Secreted to digestive system" NA NA 700000000 "Cluster 38: Basophils - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "Endoplasmic reticulum" "HPA062452: AB_2684768, HPA063471: AB_2685017" "unprognostic (6.90e-2)" "unprognostic (2.26e-1)" "unprognostic (1.69e-2)" "prognostic unfavorable (4.30e-4)" "unprognostic (3.18e-1)" "unprognostic (1.64e-1)" "unprognostic (3.29e-2)" "unprognostic (5.89e-3)" "unprognostic (1.38e-1)" "unprognostic (2.06e-3)" "unprognostic (1.10e-2)" "unprognostic (8.94e-2)" "unprognostic (7.75e-4)" "unprognostic (5.46e-3)" "unprognostic (2.13e-1)" "unprognostic (8.79e-2)" "unprognostic (4.96e-1)" 3.8 4.6 23.5 7.2 29.3 0.6 1.7 25.8 35.4 30.8 16.9 87.0 92.6 0.4 0.0 116.2 0.3 22.8 6.3 28.2 25.6 3.7 12.4 0.6 0.7 25.0 24.5 12.9 31113.6 0.0 0.7 1.7 25.7 1.1 77.8 0.3 20.9 0.3 0.5 79.7 105.4 3.1 19.4 0.7 22.8 5.1 25.6 0.8 0.4 0.0 15.2 4.2 56.9 24.7 12.0 13.7 0.7 0.0 0.2 5.9 0.1 33.6 7.7 4.1 1.6 34.3 3.0 0.0 0.2 14.9 0.2 15.0 0.0 31.7 10.1 0.4 0.2 0.0 1.1 0.0 2.7 0.0 0.0 0.2 0.0 10.8 110.2 0.3 68.8 0.2 0.0 0.0 0.0 0.2 0.7 0.4 0.2 316.6 852.5 0.0 0.0 0.0 0.0 1.7 0.3 81.2 0.2 0.0 0.0 0.5 0.0 0.0 78.3 0.0 0.0 12.8 0.0 0.0 0.0 0.1 18.1 0.0 0.1 158.7 0.0 0.0 0.2 1.5 1.2 0.0 0.2 0.4 0.5 0.0 0.0 0.0 0.0 0.4 1.5 0.0 0.0 0.3 23.5 29.3 25.8 35.4 28.2 25.6 25.0 24.5 25.7 19.4 25.6 24.7 0.1 0.0 0.0 0.7 1.9 57.1 0.6 1.3 0.0 0.2 0.1 2.8 1.0 47.1 1.2 1.8 0.0 0.0 0.1 1022.9 3.9 43.2 31.4 0.0 0.0 3.2 192.6 0.0 32.8 2040.4 0.0 0.8 39.3 0.0 8.9 0.0 0.7 4.2 0.0 0.0 4.7 146.4 0.0 0.3 12.1 79.7 1.5 1.2 7.2 3.7 5.7 0.0 0.0 3.5 1.2 478.8 969.9 0.7 0.3 12.1 1127.1 14.7 0.1 0.2 0.0 0.0 1.7 0.5 0.9 1.1 134.1 0.1 2.1 0.0 329.0 56.2 PRSS56 ENSG00000237412 "Serine protease 56" P0CW18 2 232520388-232525716 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 3.0;retina: 5.3;skeletal muscle: 9.7" "Group enriched" "Detected in some" 10 "Early spermatids: 29.0;Muller glia cells: 45.8" "Group enriched" "Detected in many" 4 "cervical cancer: 1.2;colorectal cancer: 2.5;endometrial cancer: 1.4;melanoma: 2.1;urothelial cancer: 4.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "Daudi: 1.0" "Group enriched" "Detected in some" 10 "basal ganglia: 1.8;olfactory bulb: 4.2" "Region enhanced" "Detected in many" "olfactory bulb: 14.9" NA NA "Cluster 54: Non-specific - Microtubule organization" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 5: Muller glia cells - Visual perception" "unprognostic (3.26e-1)" "unprognostic (1.98e-2)" "unprognostic (1.31e-1)" "unprognostic (3.73e-3)" "unprognostic (2.28e-1)" "unprognostic (7.15e-2)" "unprognostic (4.64e-2)" "unprognostic (1.20e-1)" 0.0 0.0 0.4 0.0 1.2 0.0 0.0 1.6 3.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.0 0.0 0.0 0.0 0.0 2.9 1.3 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 5.3 0.0 0.0 9.7 0.0 0.0 0.0 1.1 0.0 0.0 0.8 1.4 0.0 0.0 0.5 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.2 1.6 3.0 0.1 3.0 2.9 1.3 3.0 1.1 1.4 0.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.0 1.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.4 2.2 0.0 0.0 0.0 0.0 0.0 45.8 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.1 0.0 3.6 0.0 0.4 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRSS58 TRYX3 ENSG00000258223 "Serine protease 58" Q8IYP2 7 142252143-142258058 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 180 "testis: 25.8" "Group enriched" "Detected in some" 129 "Early spermatids: 640.5;Late spermatids: 243.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 29: Early spermatids - Spermatogenesis" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 640.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 243.0 3.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PSAPL1 ENSG00000178597 "Prosaposin like 1" Q6NUJ1 4 7430285-7434930 "Predicted secreted proteins" "Lipid metabolism, Sphingolipid metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "skin 1: 98.5;stomach 1: 38.6" "Cell type enriched" "Detected in some" 13 "Gastric mucus-secreting cells: 41.8" "Group enriched" "Detected in some" 5 "head and neck cancer: 0.7;melanoma: 2.5;pancreatic cancer: 2.0;stomach cancer: 3.0;urothelial cancer: 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "CACO-2: 16.6;OE19: 32.2;RPMI-8226: 24.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA038013, HPA038482" Approved Enhanced Cytosol "Secreted - unknown location" NA NA 31000 "Cluster 61: Skin - Cornification" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" Cytosol "HPA038013: AB_10673652, HPA038482: AB_2676037" "unprognostic (2.64e-2)" "unprognostic (2.40e-1)" "unprognostic (9.33e-2)" "unprognostic (2.40e-1)" "unprognostic (2.61e-1)" "unprognostic (7.90e-3)" "unprognostic (2.52e-1)" "unprognostic (2.08e-2)" "unprognostic (2.75e-1)" "unprognostic (2.63e-3)" 0.3 0.0 0.0 0.0 0.3 0.0 4.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 98.5 0.0 0.0 0.0 0.0 38.6 3.4 0.1 0.2 0.0 0.0 3.1 0.0 0.2 0.7 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 16.6 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.2 0.0 0.0 0.0 24.7 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.7 0.0 0.0 0.0 0.3 0.2 0.1 0.0 1.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 41.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 PSAT1 PSA ENSG00000135069 "Phosphoserine aminotransferase 1" Q9Y617 9 78297125-78330093 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Serine biosynthesis" "Aminotransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 175.0;liver: 267.9" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 115.5;Glandular and luminal cells: 145.9;Hepatocytes: 161.7;Proximal tubular cells: 304.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 15.1" "Lineage enriched" "Detected in many" 5 "T-cells: 15.1" "Cell line enhanced" "Detected in many" "hTCEpi: 1170.1;SK-MEL-30: 752.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB014882, CAB040567, HPA042924" Enhanced Enhanced Cytosol NA NA 2400000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 22: Non-specific - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "CAB014882: , CAB040567: , HPA042924: AB_2678223" "unprognostic (8.26e-3)" "unprognostic (4.69e-2)" "unprognostic (1.46e-1)" "prognostic unfavorable (5.62e-5)" "unprognostic (4.05e-3)" "unprognostic (1.41e-1)" "unprognostic (2.21e-3)" "unprognostic (1.86e-1)" "unprognostic (9.85e-2)" "unprognostic (2.25e-2)" "unprognostic (4.53e-2)" "unprognostic (1.07e-1)" "prognostic unfavorable (6.00e-7)" "unprognostic (3.87e-3)" "unprognostic (1.21e-1)" "unprognostic (8.07e-3)" "unprognostic (1.71e-1)" 7.8 65.8 123.3 7.3 124.6 2.0 5.1 130.5 175.0 5.1 92.8 5.9 5.4 4.3 61.6 33.2 34.7 1.7 2.7 122.4 126.5 136.7 267.9 5.1 9.3 130.2 122.4 5.6 129.1 9.7 7.6 3.0 129.9 10.0 5.5 6.2 19.2 4.0 0.6 57.2 4.5 3.3 133.6 6.0 19.4 10.4 120.3 30.0 30.3 0.5 12.4 7.3 11.2 161.6 222.8 146.0 121.1 215.6 35.1 41.2 284.7 184.3 130.4 91.8 170.6 38.2 41.9 143.2 79.8 416.9 82.9 215.3 209.1 203.6 136.4 141.2 73.9 49.2 60.8 293.3 322.0 277.6 84.6 131.1 1170.1 122.0 322.9 22.6 85.0 548.3 53.8 358.2 77.1 83.2 95.8 44.3 278.2 415.1 158.4 46.5 78.6 173.4 126.6 50.9 54.9 127.0 51.1 87.7 752.3 75.9 42.0 344.1 19.9 23.2 73.5 85.9 151.5 242.0 242.7 0.8 268.9 215.6 112.1 0.0 0.0 0.0 5.2 0.0 5.9 3.1 5.0 7.0 0.3 1.3 8.1 7.5 0.3 0.0 0.1 0.0 15.1 3.3 123.3 124.6 130.5 175.0 122.4 126.5 130.2 122.4 129.9 133.6 120.3 161.6 0.4 0.0 0.0 70.2 11.0 41.9 8.8 18.9 115.5 0.9 1.8 3.9 0.6 1.5 4.7 11.0 0.0 32.0 2.2 2.0 62.6 11.5 1.7 77.7 10.3 3.7 3.6 29.9 7.3 48.4 13.7 4.2 6.6 145.9 0.0 0.5 3.6 161.7 5.3 5.0 6.0 4.8 18.3 4.4 2.9 3.8 5.0 3.4 19.6 5.6 3.8 26.7 0.0 48.2 78.8 22.7 0.1 1.9 29.1 16.0 0.3 304.1 3.8 1.1 0.0 33.5 14.3 1.6 3.7 35.5 50.7 9.3 8.6 68.2 4.2 11.8 PSD4 "EFA6B, TIC" ENSG00000125637 "Pleckstrin and Sec7 domain containing 4" Q8NDX1 2 113157325-113209396 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 23.3" "Cell type enhanced" "Detected in many" "Hepatocytes: 51.2;Proximal enterocytes: 50.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 9.8;NB-4: 9.3" "Low region specificity" "Detected in single" "HPA034722, HPA077847" Enhanced NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" "HPA034722: AB_10669730, HPA077847: " "unprognostic (1.87e-3)" "unprognostic (1.32e-2)" "unprognostic (2.46e-2)" "unprognostic (1.88e-1)" "unprognostic (2.21e-2)" "unprognostic (1.13e-3)" "prognostic favorable (9.91e-5)" "unprognostic (6.56e-2)" "unprognostic (4.66e-2)" "unprognostic (6.19e-2)" "unprognostic (1.20e-1)" "unprognostic (1.54e-1)" "unprognostic (1.34e-2)" "prognostic favorable (4.00e-4)" "unprognostic (8.12e-2)" "unprognostic (2.41e-1)" "unprognostic (3.60e-3)" 1.7 13.7 1.4 3.1 1.3 3.7 3.9 0.5 1.2 2.3 0.7 7.0 2.0 0.7 4.0 10.8 1.7 1.3 0.8 1.0 1.0 5.2 21.2 5.8 3.9 1.0 0.8 0.5 11.6 3.0 3.4 0.9 1.1 8.7 1.9 0.5 11.3 1.2 0.6 9.0 17.7 0.4 0.9 23.3 12.4 1.5 1.5 5.9 10.1 0.3 4.0 3.7 4.2 0.9 5.7 1.0 0.3 0.1 0.0 0.0 6.1 0.4 2.2 0.4 0.5 1.5 8.1 9.8 1.2 0.2 1.7 7.4 0.0 2.0 0.1 8.3 0.1 4.1 0.8 2.2 0.1 6.9 6.9 0.1 1.9 0.2 0.5 0.9 0.0 3.8 3.9 4.1 0.0 3.2 7.1 9.3 0.1 1.8 1.1 0.1 0.1 4.3 0.4 1.4 0.5 0.0 0.7 5.1 0.0 0.2 1.6 5.6 0.1 0.3 0.2 0.2 1.6 5.0 4.0 3.0 0.9 3.3 0.1 1.7 0.9 1.7 2.0 0.6 1.7 1.0 1.5 1.8 0.6 1.2 1.7 1.9 3.9 2.4 0.7 1.5 1.1 1.4 1.4 1.3 0.5 1.2 1.0 1.0 1.0 0.8 1.1 0.9 1.5 0.9 0.9 19.2 12.0 7.5 28.6 12.7 10.4 7.6 13.1 0.3 22.5 11.2 1.8 11.5 5.8 33.1 0.0 20.7 41.6 39.1 0.0 21.3 0.3 9.0 1.6 2.1 7.2 13.0 0.9 23.6 11.2 3.0 31.1 20.4 3.8 2.9 2.9 51.2 12.1 3.3 1.7 10.7 4.1 13.8 17.0 0.9 0.9 14.3 1.8 2.8 13.8 10.1 47.4 2.5 0.2 23.1 17.8 0.0 18.3 15.8 50.3 7.1 4.6 0.4 0.0 3.0 1.7 0.2 1.1 17.4 15.8 7.5 28.2 1.7 18.6 11.1 PSMC2 "MSS1, Nbla10058, S7" ENSG00000161057 "Proteasome 26S subunit, ATPase 2" P35998 7 103328570-103370346 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 231.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019238, HPA049621" Supported Supported "Cytosol,Cytoplasmic bodies" NA NA 190000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Cytosol, Cytoplasmic bodies" "HPA019238: AB_1855834, HPA049621: AB_2680833" "unprognostic (4.00e-2)" "unprognostic (6.66e-2)" "unprognostic (2.55e-1)" "unprognostic (3.58e-1)" "unprognostic (1.57e-3)" "unprognostic (3.55e-2)" "unprognostic (2.08e-2)" "unprognostic (6.08e-2)" "unprognostic (7.73e-2)" "unprognostic (1.49e-2)" "unprognostic (1.07e-1)" "unprognostic (4.71e-1)" "unprognostic (5.09e-3)" "unprognostic (1.30e-1)" "unprognostic (2.18e-1)" "unprognostic (9.76e-2)" "unprognostic (1.41e-1)" 34.1 33.6 19.6 31.7 21.6 32.0 25.6 23.7 29.5 26.2 24.3 26.2 25.2 23.5 27.8 27.2 23.1 22.0 35.9 20.5 22.9 39.9 54.2 23.5 29.6 22.5 21.0 21.2 16.5 41.4 16.1 30.9 22.3 27.1 22.8 22.3 23.8 26.4 87.2 27.6 24.5 29.6 24.3 22.4 29.5 25.8 21.7 42.4 29.2 77.1 33.5 34.3 17.7 24.8 133.5 78.3 84.4 98.2 93.0 69.7 58.5 102.5 97.9 123.7 122.7 92.7 97.3 100.1 199.2 94.7 168.1 71.0 109.2 76.6 128.7 153.3 68.0 90.5 57.9 57.8 65.2 149.0 84.9 55.3 50.2 122.5 38.9 60.9 89.8 70.4 190.1 98.2 104.2 135.8 165.0 74.2 98.7 109.6 95.2 73.8 108.4 93.8 80.6 64.2 65.3 64.9 97.6 123.9 89.6 92.9 56.6 73.3 91.5 80.9 106.6 174.6 153.8 98.9 274.8 191.3 118.1 143.7 138.5 140.0 53.4 52.7 44.7 81.6 51.5 47.5 51.1 47.9 75.3 40.6 46.3 47.3 7.3 58.4 98.2 42.3 93.3 74.2 19.6 21.6 23.7 29.5 20.5 22.9 22.5 21.0 22.3 24.3 21.7 24.8 36.2 48.1 29.5 18.3 33.8 39.8 41.4 131.8 24.5 36.0 23.5 27.2 61.8 40.0 73.9 27.6 14.6 172.2 34.4 22.5 66.5 113.9 118.9 32.3 33.9 48.5 8.4 64.6 27.9 96.4 110.6 49.7 27.5 24.9 56.4 35.5 34.2 48.5 134.6 26.9 25.1 36.9 93.6 48.5 40.4 33.2 58.4 46.1 32.0 15.9 62.4 69.5 40.2 21.1 32.8 87.3 38.5 64.3 45.0 34.7 36.9 88.8 52.5 49.1 59.2 43.7 105.2 96.3 47.2 23.6 42.9 231.8 39.5 49.1 32.0 42.9 PSMD11 "MGC3844, p44.5, Rpn6, S9" ENSG00000108671 "Proteasome 26S subunit, non-ATPase 11" O00231 17 32444379-32483319 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 308.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042275, HPA067433" Approved Approved "Nucleoplasm,Golgi apparatus" NA NA 95000 "Cluster 44: Non-specific - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Golgi apparatus" "HPA042275: AB_10794793, HPA067433: AB_2685838" "unprognostic (1.16e-1)" "unprognostic (2.71e-1)" "unprognostic (6.94e-2)" "unprognostic (2.86e-2)" "unprognostic (2.01e-1)" "unprognostic (1.20e-2)" "prognostic unfavorable (6.33e-6)" "unprognostic (2.64e-2)" "unprognostic (3.97e-1)" "unprognostic (8.10e-2)" "unprognostic (5.88e-2)" "unprognostic (9.17e-3)" "prognostic unfavorable (5.73e-6)" "unprognostic (9.39e-3)" "unprognostic (6.65e-2)" "unprognostic (2.90e-1)" "unprognostic (2.17e-2)" 26.9 26.5 25.6 29.4 26.4 34.5 22.6 24.6 29.5 22.8 20.3 27.3 27.2 28.8 23.1 36.3 21.8 22.7 37.0 26.0 25.6 30.1 37.7 24.3 30.2 27.0 25.3 20.6 25.9 35.0 18.5 34.1 28.1 25.0 32.0 23.8 23.3 21.8 96.0 33.8 23.2 35.0 24.4 24.0 22.9 34.2 25.9 38.4 21.6 58.6 39.1 34.0 24.8 31.2 127.0 136.8 98.4 106.2 65.4 48.4 103.8 71.5 90.0 151.9 122.0 139.9 111.5 99.1 110.7 77.0 145.9 143.0 114.5 98.5 147.8 50.9 81.2 81.0 68.7 108.3 63.3 95.5 81.6 43.7 51.0 134.3 91.8 49.0 108.7 87.0 155.5 110.9 90.8 78.0 143.1 57.4 134.5 67.4 68.8 89.2 127.2 132.4 75.2 92.2 86.3 58.8 89.8 63.4 71.0 100.3 154.2 45.1 77.8 84.3 99.5 105.6 166.5 62.2 105.0 129.1 122.5 74.8 145.2 48.3 41.2 26.7 40.2 41.8 44.2 36.3 39.1 40.6 46.6 34.2 34.5 36.4 19.1 47.7 45.6 38.2 51.5 45.6 25.6 26.4 24.6 29.5 26.0 25.6 27.0 25.3 28.1 24.4 25.9 31.2 62.7 48.1 31.5 36.6 56.3 126.9 108.7 116.3 44.9 44.5 47.8 40.8 71.9 41.5 78.0 25.8 31.3 178.2 57.8 87.5 80.3 117.8 205.4 45.8 46.2 69.7 48.8 100.8 36.0 107.3 146.1 63.8 43.8 59.9 45.7 79.8 55.3 107.0 92.3 37.0 36.4 58.7 77.3 48.4 72.6 48.0 49.0 61.1 26.6 15.9 77.5 63.1 40.2 33.2 55.6 117.2 48.0 48.5 79.3 131.9 66.4 120.6 52.6 43.3 52.6 68.0 189.7 152.7 98.4 85.3 117.5 308.9 54.8 52.0 67.6 109.5 PSMD6 "KIAA0107, p44S10, Rpn7, S10" ENSG00000163636 "Proteasome 26S subunit, non-ATPase 6" Q15008 3 64010550-64024010 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 285.7" "Cell type enhanced" "Detected in all" "Early spermatids: 513.3;Late spermatids: 717.7;Spermatocytes: 336.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 7 "MCF7: 1458.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036921, HPA036922" Uncertain NA NA 120000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" "HPA036921: AB_2675383, HPA036922: AB_10670850" "unprognostic (3.44e-2)" "unprognostic (2.03e-1)" "unprognostic (4.76e-3)" "unprognostic (1.95e-1)" "unprognostic (2.43e-1)" "unprognostic (1.82e-1)" "prognostic unfavorable (1.68e-4)" "unprognostic (8.65e-2)" "unprognostic (1.38e-1)" "unprognostic (1.95e-3)" "unprognostic (6.69e-2)" "unprognostic (4.73e-2)" "unprognostic (4.06e-3)" "unprognostic (4.20e-2)" "unprognostic (1.89e-1)" "unprognostic (9.55e-2)" "unprognostic (8.22e-3)" 47.2 67.9 43.9 43.3 45.2 115.0 49.5 47.5 63.2 37.1 44.7 46.2 34.0 43.1 60.1 61.4 35.2 28.2 74.9 46.2 47.5 62.9 74.9 37.9 50.2 47.5 47.5 32.8 285.7 72.9 30.8 54.2 49.2 42.1 43.4 48.4 43.7 45.6 160.8 54.6 34.8 49.5 49.2 38.8 46.1 120.2 45.2 54.8 40.3 90.9 63.9 52.3 40.4 49.0 98.4 102.5 141.1 99.5 97.6 87.0 125.9 136.3 128.8 221.5 162.4 193.0 79.8 136.9 57.6 132.4 154.7 66.1 166.4 144.7 207.3 141.1 104.6 183.6 76.3 128.2 142.9 204.9 112.2 93.7 100.8 184.2 80.3 107.4 141.5 117.7 187.3 86.1 157.8 1458.7 141.0 125.3 180.7 157.3 71.9 117.2 101.1 132.4 177.1 140.7 52.1 85.0 101.6 85.4 136.2 123.4 74.3 125.0 125.7 98.1 106.5 145.2 217.1 108.2 171.0 204.1 144.3 190.8 116.1 99.2 113.9 140.3 103.4 133.0 107.3 124.7 114.0 112.9 120.1 120.3 113.6 110.5 139.4 111.5 139.8 84.0 137.1 167.2 43.9 45.2 47.5 63.2 46.2 47.5 47.5 47.5 49.2 49.2 45.2 49.0 46.4 32.1 43.2 7.5 48.7 62.1 71.7 152.5 27.9 37.0 33.9 34.9 100.0 22.8 86.4 44.1 22.9 197.8 47.3 27.6 86.1 104.0 513.3 49.0 42.3 55.3 25.8 99.9 11.7 133.7 102.3 47.6 27.0 48.9 45.6 46.7 28.9 47.4 92.2 33.7 10.9 27.3 73.2 38.1 40.5 717.7 51.9 51.7 48.0 4.7 71.0 81.8 39.1 10.1 15.4 87.1 30.4 51.1 58.1 44.7 29.7 95.9 73.0 41.2 59.2 41.3 145.8 336.9 131.3 53.4 69.9 290.6 50.4 68.7 35.8 66.1 PSME3IP1 "C16orf94, FAM192A, NIP30, PIP30" ENSG00000172775 "Proteasome activator subunit 3 interacting protein 1" Q9GZU8 16 57152466-57186116 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 82.3;Cytotrophoblasts: 56.7;Extravillous trophoblasts: 59.5;Hofbauer cells: 64.6;Syncytiotrophoblasts: 53.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054382, HPA059652" Uncertain Supported Nucleoplasm,Vesicles NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm Vesicles "HPA054382: AB_2682469, HPA059652: AB_2684095" "unprognostic (1.69e-2)" "unprognostic (5.20e-2)" "unprognostic (1.36e-1)" "unprognostic (9.20e-3)" "unprognostic (4.69e-3)" "unprognostic (2.45e-2)" "unprognostic (1.01e-2)" "unprognostic (2.22e-1)" "unprognostic (6.09e-2)" "unprognostic (1.52e-2)" "unprognostic (1.41e-1)" "unprognostic (4.19e-1)" "unprognostic (3.00e-1)" "unprognostic (3.87e-3)" "unprognostic (4.14e-2)" "unprognostic (1.58e-1)" "unprognostic (2.56e-3)" 48.8 50.2 80.5 72.9 93.9 151.0 66.7 85.8 99.0 52.4 83.8 75.4 67.6 54.1 64.7 63.5 54.1 47.3 59.2 78.4 89.7 66.3 62.6 57.6 94.8 91.7 87.3 54.6 55.3 76.7 65.3 56.0 87.3 64.7 87.5 75.2 55.2 50.3 79.0 90.3 76.1 52.3 87.9 93.3 62.6 96.8 85.8 85.0 71.5 66.0 96.5 53.3 56.1 103.7 119.3 148.6 163.6 109.8 70.3 86.2 153.4 138.3 102.3 166.3 107.1 141.3 122.5 179.2 150.6 105.8 84.2 155.9 114.4 137.9 167.1 80.3 92.1 125.0 141.6 148.3 101.0 154.8 170.8 86.6 134.8 158.2 127.4 101.8 121.0 134.4 170.1 56.5 110.8 88.2 169.4 143.2 105.1 88.0 111.3 205.6 236.9 174.5 113.1 96.4 116.3 133.9 250.2 105.2 92.7 113.0 87.1 105.9 120.2 122.0 102.3 90.2 103.7 133.2 113.1 228.6 125.0 109.7 119.6 170.3 78.3 124.1 47.6 93.0 46.8 83.1 45.8 44.7 90.0 77.8 47.0 49.1 107.6 57.1 123.4 62.4 69.2 68.1 80.5 93.9 85.8 99.0 78.4 89.7 91.7 87.3 87.3 87.9 85.8 103.7 16.9 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 82.3 0.0 0.0 0.0 0.0 56.7 10.2 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 59.5 16.8 0.0 0.0 0.0 0.0 0.0 0.0 64.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 0.0 0.0 0.0 0.0 53.1 1.5 0.0 0.0 0.0 PSMF1 PI31 ENSG00000125818 "Proteasome inhibitor subunit 1" Q92530 20 1113240-1189415 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 15 "Early spermatids: 1242.7;Late spermatids: 4603.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041122, HPA041300" Approved Enhanced Cytosol NA NA 160000 "Cluster 2: Granulocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 39: CACO-2 - Unknown function" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "HPA041122: AB_10805838, HPA041300: AB_10794370" "unprognostic (1.79e-2)" "unprognostic (8.96e-2)" "unprognostic (7.22e-2)" "unprognostic (3.88e-2)" "unprognostic (1.68e-3)" "unprognostic (1.43e-2)" "unprognostic (9.14e-3)" "unprognostic (1.56e-1)" "unprognostic (7.03e-2)" "unprognostic (4.71e-1)" "unprognostic (2.45e-1)" "unprognostic (7.41e-2)" "unprognostic (3.72e-3)" "unprognostic (1.10e-1)" "unprognostic (1.36e-1)" "unprognostic (4.18e-2)" "unprognostic (8.32e-2)" 49.7 37.8 32.8 41.8 33.8 53.7 43.4 33.5 35.7 44.3 33.2 46.0 44.2 42.5 27.8 47.7 37.8 26.8 52.0 31.5 33.0 42.4 72.6 43.4 40.9 35.7 33.2 43.8 56.8 43.1 35.2 26.3 34.2 33.3 31.7 32.9 38.8 32.5 128.3 47.2 42.9 36.9 32.8 38.3 44.0 107.6 36.7 41.2 37.7 83.6 39.9 42.3 39.1 35.5 141.5 126.4 29.7 70.3 63.8 66.5 50.8 83.8 64.9 76.1 67.2 118.2 96.4 71.2 56.1 90.3 79.3 123.8 78.9 143.3 95.1 42.3 47.0 99.1 20.8 217.0 83.7 120.6 33.2 67.9 82.3 85.3 132.7 45.9 83.2 55.3 101.5 138.8 62.9 75.4 156.3 107.9 42.6 81.4 79.2 74.5 62.2 118.6 67.7 117.9 75.4 52.4 92.3 159.1 77.3 28.5 108.8 43.3 96.8 95.3 63.8 111.3 115.6 85.9 185.5 77.5 41.8 81.3 74.7 123.8 65.2 123.3 49.8 80.2 57.8 73.2 66.2 54.4 66.3 69.0 59.7 52.8 71.7 58.5 83.0 37.8 81.6 69.4 32.8 33.8 33.5 35.7 31.5 33.0 35.7 33.2 34.2 32.8 36.7 35.5 48.7 35.3 44.2 34.0 58.3 41.2 59.1 81.0 33.0 32.7 40.5 41.5 55.4 31.5 44.8 40.5 4.2 68.0 48.8 51.9 82.2 102.5 1242.7 27.3 38.4 47.4 67.4 190.1 25.2 103.8 88.9 50.2 48.4 28.1 49.5 46.5 50.0 70.0 100.3 21.9 25.4 57.9 34.6 56.3 56.7 4603.4 77.3 58.2 51.6 34.7 76.1 64.3 55.6 22.1 38.1 99.4 75.3 88.8 66.8 69.0 103.3 80.7 32.4 33.1 118.3 36.7 65.0 97.4 90.7 52.1 48.6 74.0 55.0 73.0 62.6 68.8 PSMG1 "c21-LRP, DSCR2, LRPC21, PAC1" ENSG00000183527 "Proteasome assembly chaperone 1" O95456 21 39174769-39183488 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 40.3" "Group enriched" "Detected in all" 4 "Early spermatids: 673.8;Spermatocytes: 544.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057193, HPA070225" Approved Enhanced "Nucleoplasm,Golgi apparatus,Cytosol" No No "Cluster 44: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 36: HEL - Hemostasis" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Golgi apparatus, Cytosol" "HPA057193: AB_2683363, HPA070225: AB_2686236" "unprognostic (1.52e-2)" "unprognostic (1.24e-1)" "unprognostic (1.27e-1)" "unprognostic (2.34e-1)" "unprognostic (2.10e-1)" "unprognostic (9.38e-2)" "unprognostic (5.06e-3)" "unprognostic (2.02e-1)" "unprognostic (1.66e-2)" "unprognostic (5.09e-2)" "unprognostic (1.09e-1)" "unprognostic (7.99e-2)" "prognostic unfavorable (3.58e-5)" "unprognostic (2.84e-1)" "unprognostic (8.98e-2)" "unprognostic (1.32e-2)" "unprognostic (4.17e-3)" 7.5 9.8 4.0 9.1 4.0 17.3 6.8 2.7 5.5 7.3 2.5 10.5 8.9 7.8 4.8 11.8 6.4 5.4 8.3 4.6 3.8 9.7 15.9 5.7 8.9 2.2 2.4 7.2 10.8 5.1 8.0 7.7 3.2 5.5 9.9 4.9 7.3 3.2 13.8 7.1 8.2 5.1 2.1 6.3 7.1 40.3 3.7 6.3 10.8 5.6 6.2 7.8 7.4 4.0 104.0 34.7 23.5 32.9 12.3 15.1 65.0 55.3 25.9 44.8 28.2 66.6 26.9 113.7 28.9 17.1 38.1 28.5 40.3 30.3 30.2 48.9 61.6 209.6 52.4 83.6 21.9 101.0 40.4 18.9 24.6 46.2 46.5 9.8 24.9 47.0 160.4 61.9 27.2 58.2 63.0 54.7 82.2 38.9 53.5 99.6 29.8 115.8 19.1 30.4 77.6 22.7 70.4 39.1 57.4 4.0 36.6 51.4 26.7 50.1 16.8 66.7 79.9 46.4 79.3 96.8 42.0 170.4 38.6 10.6 6.8 3.9 10.5 9.0 12.3 12.0 14.7 12.4 12.2 10.6 11.5 10.3 0.6 7.5 9.1 11.3 13.7 7.9 4.0 4.0 2.7 5.5 4.6 3.8 2.2 2.4 3.2 2.1 3.7 4.0 23.7 6.4 17.6 5.2 17.8 136.0 44.1 68.6 43.9 14.2 31.3 39.0 24.8 22.8 39.9 20.2 4.2 108.9 12.6 14.7 66.5 50.8 673.8 20.8 36.5 26.3 29.9 63.3 7.5 49.7 118.6 31.8 18.8 21.6 36.1 26.2 18.9 32.7 59.5 8.4 8.0 45.7 69.2 17.7 35.5 88.4 31.7 25.0 46.2 3.7 24.4 18.0 12.3 3.5 5.9 32.4 20.0 33.1 31.7 41.5 30.6 89.4 20.8 19.7 26.3 29.5 31.3 544.1 98.7 51.7 97.7 54.5 20.1 54.7 56.9 27.9 PTBP3 "DKFZp781I1117, ROD1" ENSG00000119314 "Polypyrimidine tract binding protein 3" O95758 9 112217716-112333664 "Predicted intracellular proteins" "Differentiation, Erythrocyte maturation, mRNA processing, mRNA splicing" "Repressor, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048374 Approved Nucleoplasm NA NA "Cluster 10: Basophils - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 28: BEWO - Transcription regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA048374: AB_2680376" "unprognostic (6.12e-2)" "unprognostic (3.05e-1)" "unprognostic (2.77e-2)" "unprognostic (1.33e-1)" "unprognostic (2.44e-1)" "unprognostic (2.12e-1)" "unprognostic (4.38e-3)" "prognostic unfavorable (2.10e-4)" "unprognostic (1.39e-2)" "unprognostic (6.23e-2)" "prognostic unfavorable (1.22e-4)" "unprognostic (1.17e-1)" "prognostic favorable (2.51e-4)" "unprognostic (1.72e-2)" "unprognostic (4.99e-2)" "unprognostic (3.04e-2)" "unprognostic (5.10e-2)" 14.7 11.6 5.5 31.0 9.6 40.9 21.7 5.6 6.3 15.3 5.7 31.8 28.6 13.3 15.1 37.1 12.3 20.9 7.6 5.7 10.7 25.6 15.6 21.5 36.7 5.4 5.8 10.9 14.3 11.1 7.4 24.8 5.3 11.5 34.1 8.6 17.7 9.3 5.9 28.7 31.1 12.5 4.6 28.5 33.3 23.7 7.0 46.2 19.6 7.1 39.5 37.0 17.6 5.9 62.3 64.3 24.2 21.0 20.9 22.8 123.0 24.8 20.1 29.9 30.9 74.3 90.7 70.3 26.9 32.5 23.8 86.5 34.0 71.0 39.6 79.7 11.7 71.5 25.1 52.6 26.6 95.7 83.7 25.8 47.2 40.3 55.1 19.1 51.9 53.2 97.6 64.6 34.7 57.8 93.7 25.9 38.3 95.6 21.7 60.6 82.0 35.9 44.4 81.6 30.0 19.4 49.3 63.9 24.1 51.6 75.4 42.9 40.5 26.3 35.3 38.2 31.3 32.6 86.6 62.9 22.7 47.6 26.4 23.0 8.8 16.7 10.8 10.3 11.3 7.0 7.8 8.8 9.9 8.6 6.2 7.3 32.5 5.8 14.4 16.1 9.1 6.8 5.5 9.6 5.6 6.3 5.7 10.7 5.4 5.8 5.3 4.6 7.0 5.9 75.5 28.9 68.6 18.6 76.8 80.2 52.2 47.8 87.0 7.7 49.9 31.0 9.5 45.8 65.1 114.0 18.8 39.0 129.1 111.1 29.4 41.6 71.2 83.1 53.1 53.1 90.4 75.1 54.2 71.2 107.3 32.5 90.7 115.3 65.8 31.6 46.8 31.4 57.5 8.4 37.5 76.8 24.4 110.8 89.4 131.0 21.8 104.1 28.4 89.0 116.7 3.6 62.8 45.2 26.5 115.9 66.6 18.8 54.6 81.7 62.3 31.5 86.2 16.1 19.7 34.5 36.9 25.1 20.6 110.5 104.0 35.0 77.8 21.6 84.7 190.7 PTCH1 "BCNS, NBCCS, PTCH" ENSG00000185920 "Patched 1" Q13635 9 95442980-95517057 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Receptor "Cancer-related genes, Disease variant, Holoprosencephaly, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 26.7" "Cell type enhanced" "Detected in many" "Late spermatids: 237.5;Leydig cells: 191.0;Peritubular cells: 444.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 6.1" "Lineage enriched" "Detected in single" 9 "T-cells: 6.1" "Cell line enhanced" "Detected in many" "NTERA-2: 29.6;WM-115: 71.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013717, HPA075072" Uncertain Approved "Golgi apparatus" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 52: Non-specific - Transcription" "Golgi apparatus" "CAB013717: , HPA075072: AB_2686733" "unprognostic (1.46e-1)" "unprognostic (1.06e-1)" "unprognostic (3.16e-1)" "unprognostic (1.79e-2)" "unprognostic (3.22e-2)" "unprognostic (9.01e-2)" "unprognostic (2.13e-1)" "unprognostic (3.54e-3)" "unprognostic (2.63e-1)" "unprognostic (8.66e-3)" "unprognostic (1.52e-2)" "unprognostic (2.82e-1)" "unprognostic (1.13e-6)" "unprognostic (8.63e-2)" "unprognostic (4.40e-2)" "unprognostic (2.76e-1)" "unprognostic (2.82e-1)" 3.0 3.5 9.5 4.0 11.6 0.7 2.8 24.6 5.6 26.7 2.7 11.3 8.1 15.6 2.7 2.9 7.1 8.1 2.9 4.7 17.8 4.6 2.2 5.5 2.2 16.0 12.7 5.0 6.4 2.5 2.1 3.8 8.0 6.8 12.3 8.3 7.5 4.0 3.0 3.2 11.6 2.4 7.0 3.3 12.5 14.5 24.0 2.1 4.7 4.8 3.0 7.2 2.9 4.5 10.1 4.7 20.3 12.9 3.0 5.0 11.4 1.9 1.7 2.2 1.4 4.9 4.8 8.0 3.3 3.8 4.4 22.3 11.7 1.6 1.4 7.9 7.8 0.0 4.8 2.3 2.7 0.2 4.2 4.7 2.4 2.2 1.4 4.3 4.2 3.5 7.3 9.1 1.0 1.9 0.1 3.2 29.6 7.2 1.8 0.0 15.5 4.2 1.6 1.5 13.8 7.0 7.1 6.8 2.9 18.8 1.8 2.1 1.1 2.6 12.9 13.6 1.5 18.0 16.8 5.3 3.8 3.9 71.0 0.0 0.0 0.0 6.1 0.0 3.3 0.7 1.1 2.5 0.0 0.2 1.9 2.2 0.0 0.3 0.0 0.0 1.2 1.7 9.5 11.6 24.6 5.6 4.7 17.8 16.0 12.7 8.0 7.0 24.0 4.5 6.0 0.0 6.4 49.0 3.0 4.0 2.7 3.0 4.6 20.3 3.5 4.6 5.9 25.8 2.7 0.0 41.7 3.0 11.8 2.0 5.9 3.5 88.4 12.2 89.8 5.4 21.7 0.4 15.2 4.2 1.9 27.2 1.1 11.0 1.3 2.6 6.4 2.9 0.8 20.2 10.7 11.0 4.1 0.9 1.2 237.5 191.0 1.4 12.4 4.7 0.8 55.6 54.6 39.7 20.5 2.4 3.1 444.5 3.1 4.9 3.1 1.6 5.5 13.4 39.5 4.8 9.4 4.4 35.5 3.0 4.4 1.4 6.5 71.7 4.7 1.4 PTCH2 ENSG00000117425 "Patched 2" Q9Y6C5 1 44819844-44843253 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Receptor "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "ovary: 24.6;parathyroid gland: 59.1;salivary gland: 75.2;testis: 25.6" "Cell type enhanced" "Detected in many" "Leydig cells: 107.8;Peritubular cells: 68.1;Plasma cells: 67.1;Theca cells: 138.7" "Cancer enhanced" "Detected in many" "testis cancer: 9.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-266/84: 11.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA046839 Supported "Nucleoli,Plasma membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 16: U-266 - Nucleosome" "Cluster 52: Non-specific - Transcription" "Plasma membrane" Nucleoli "HPA046839: " "unprognostic (6.54e-5)" "unprognostic (1.05e-1)" "unprognostic (7.29e-3)" "unprognostic (3.65e-3)" "unprognostic (3.89e-1)" "unprognostic (7.42e-3)" "unprognostic (3.01e-1)" "unprognostic (2.94e-2)" "unprognostic (1.51e-1)" "unprognostic (8.67e-2)" "prognostic favorable (5.74e-5)" "unprognostic (2.92e-1)" "unprognostic (5.74e-6)" "unprognostic (1.55e-2)" "unprognostic (4.86e-2)" "unprognostic (6.31e-2)" "unprognostic (6.81e-2)" 4.2 3.1 6.1 0.8 3.5 9.4 3.4 6.8 6.8 5.1 3.6 3.6 1.0 6.4 1.6 0.9 4.3 2.5 1.3 3.1 4.4 1.3 1.3 1.0 2.3 2.9 4.8 24.6 1.0 59.1 9.9 0.3 2.0 3.0 0.9 3.6 75.2 1.3 2.0 3.6 1.8 1.2 1.6 2.4 2.0 25.6 6.5 0.8 4.6 0.8 0.7 3.1 3.4 4.8 0.2 0.3 1.0 2.5 0.8 0.9 1.0 0.8 1.6 0.5 0.4 0.2 0.4 1.1 0.4 0.4 0.5 0.0 1.1 0.0 0.2 2.1 1.9 0.6 1.0 0.8 0.3 0.7 1.1 0.3 0.4 1.0 0.1 1.7 0.1 1.0 0.7 1.1 0.0 0.5 1.4 2.1 0.3 0.1 0.4 1.0 0.2 0.5 0.2 0.0 1.5 0.6 0.3 0.4 0.8 0.5 0.2 1.2 0.1 0.2 0.5 1.3 0.5 1.9 11.6 3.2 0.6 3.0 0.4 2.5 1.9 0.1 0.5 0.9 1.0 1.0 0.6 0.6 1.2 1.4 0.7 0.6 0.6 0.9 0.9 3.6 0.3 0.2 6.1 3.5 6.8 6.8 3.1 4.4 2.9 4.8 2.0 1.6 6.5 4.8 2.8 0.0 1.1 14.0 13.4 0.5 0.7 1.0 0.6 0.8 4.8 8.0 1.0 7.2 1.0 1.8 2.1 2.4 6.8 7.8 0.0 5.5 2.3 9.3 13.5 2.7 11.5 1.3 23.7 1.8 1.6 14.3 28.1 8.5 0.0 4.4 0.7 7.9 6.7 8.4 27.3 4.9 2.0 24.5 2.2 8.0 107.8 17.3 0.0 5.6 3.9 2.4 2.1 9.5 2.6 2.1 2.5 68.1 67.1 0.8 13.6 0.2 1.7 1.2 13.1 5.4 5.6 5.0 3.6 0.6 1.6 2.3 7.5 138.7 5.5 0.2 PTEN "BZS, MHAM, MMAC1, PTEN1, TEP1" ENSG00000171862 "Phosphatase and tensin homolog" P60484 10 87863625-87971930 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Lipid metabolism, Neurogenesis" "Hydrolase, Protein phosphatase" "Autism spectrum disorder, Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 60.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004076, HPA031335" Approved Supported Nucleoplasm,Cytosol "Intracellular and membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 24: NB-4 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm Cytosol "CAB004076: AB_390810, HPA031335: AB_2797221" "unprognostic (8.72e-2)" "unprognostic (2.45e-1)" "unprognostic (5.43e-1)" "unprognostic (1.50e-2)" "unprognostic (3.71e-2)" "unprognostic (1.30e-1)" "unprognostic (2.18e-1)" "unprognostic (2.08e-1)" "unprognostic (2.07e-1)" "unprognostic (6.87e-2)" "unprognostic (9.77e-2)" "unprognostic (2.71e-1)" "prognostic unfavorable (7.35e-4)" "unprognostic (1.57e-1)" "unprognostic (2.73e-1)" "unprognostic (6.54e-3)" "unprognostic (2.41e-1)" 64.0 25.4 17.8 18.6 19.3 12.9 47.6 34.5 23.4 54.8 15.6 28.1 12.9 27.4 18.6 28.3 35.2 15.6 29.7 20.4 18.4 22.6 39.2 39.5 21.4 16.6 17.8 28.0 33.2 11.9 17.3 30.5 16.4 26.3 14.6 30.0 19.6 16.5 23.7 25.9 24.5 22.2 14.5 40.0 25.6 28.2 19.7 31.8 26.1 14.0 16.5 28.1 38.4 17.6 23.5 10.8 12.3 11.2 28.5 19.7 10.9 12.5 28.0 14.5 20.4 10.9 28.0 28.1 8.0 20.9 8.3 14.1 16.6 14.3 22.8 14.1 4.7 9.3 28.5 13.8 30.1 31.9 15.3 13.5 38.7 18.0 23.7 60.3 20.8 17.7 7.0 72.6 13.5 18.1 17.8 56.3 4.6 19.9 0.0 27.6 6.4 20.8 22.9 13.4 4.5 19.9 16.6 7.9 23.0 9.7 21.9 45.2 17.9 44.6 10.8 18.3 10.1 23.9 32.9 30.7 14.6 29.2 2.9 21.3 14.2 25.8 6.8 21.8 7.2 7.9 7.2 6.6 10.3 6.8 8.3 8.3 60.5 8.9 15.6 8.2 7.0 4.5 17.8 19.3 34.5 23.4 20.4 18.4 16.6 17.8 16.4 14.5 19.7 17.6 67.2 35.3 63.3 83.6 48.3 56.1 57.4 31.5 47.3 113.0 49.4 41.9 46.5 57.2 31.2 29.5 39.6 25.8 64.4 57.7 33.2 24.7 70.1 40.0 114.5 56.0 31.2 52.0 141.0 30.0 62.2 79.3 39.8 33.6 25.4 39.6 53.9 64.1 35.0 45.4 132.4 44.7 12.2 206.1 97.2 92.1 56.8 105.2 62.2 196.8 101.5 61.6 44.3 139.2 95.7 30.6 39.7 54.5 39.3 45.1 50.1 38.0 31.2 61.2 92.1 66.4 170.7 33.5 25.4 45.2 60.1 57.3 46.3 44.7 46.1 64.0 PTPN4 PTPMEG ENSG00000088179 "Protein tyrosine phosphatase non-receptor type 4" P29074 2 119759922-119984899 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 37.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 224.3;Horizontal cells: 161.5;Inhibitory neurons: 187.5;NK-cells: 247.2;Oligodendrocyte precursor cells: 200.6" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 37.3" "Group enriched" "Detected in many" 4 "gdT-cell: 35.0;MAIT T-cell: 28.1;memory CD4 T-cell: 16.9;memory CD8 T-cell: 27.9;naive CD8 T-cell: 19.2;NK-cell: 24.4;T-reg: 11.0" "Group enriched" "Detected in many" 16 "NK-cells: 24.4;T-cells: 35.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019351 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 44: HDLM-2 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm "Plasma membrane, Cytosol" "HPA019351: AB_1855928" "unprognostic (1.45e-1)" "unprognostic (1.22e-1)" "unprognostic (1.07e-1)" "unprognostic (7.63e-2)" "unprognostic (9.00e-2)" "unprognostic (9.57e-2)" "unprognostic (2.34e-1)" "prognostic favorable (5.16e-4)" "unprognostic (3.31e-2)" "unprognostic (3.34e-3)" "unprognostic (3.13e-1)" "unprognostic (1.10e-1)" "unprognostic (3.34e-2)" "unprognostic (1.74e-1)" "unprognostic (1.87e-1)" "unprognostic (4.08e-2)" "unprognostic (1.81e-1)" 4.5 3.8 5.9 3.6 5.0 5.1 4.7 37.3 10.1 5.7 0.0 3.4 5.1 4.1 4.2 4.1 5.5 3.7 5.7 5.2 2.7 7.4 4.2 5.2 5.4 0.1 9.6 5.2 2.8 6.3 3.5 2.5 1.4 3.5 2.4 12.1 4.1 2.5 8.0 3.0 2.8 2.8 0.0 5.9 5.7 4.9 12.6 8.1 14.0 12.8 4.2 3.2 2.6 5.9 7.4 4.3 5.0 7.3 4.8 5.0 9.1 3.2 9.3 1.8 4.9 6.2 10.9 4.1 7.6 3.5 5.2 5.3 4.4 5.1 4.8 12.6 3.6 3.7 3.5 6.1 3.2 3.9 2.6 4.5 9.6 8.5 3.7 6.0 8.2 4.8 5.7 4.8 5.0 5.0 5.2 4.4 7.3 4.0 6.9 3.4 9.6 6.9 6.7 10.0 6.8 8.5 4.2 5.8 4.0 4.0 2.8 2.4 10.7 0.0 6.1 1.9 4.0 8.9 13.7 6.6 4.7 0.1 3.0 0.3 0.2 1.8 35.0 0.5 28.1 0.6 16.9 27.9 0.5 0.6 5.2 19.2 0.6 24.4 0.7 0.3 11.0 10.4 5.9 5.0 37.3 10.1 5.2 2.7 0.1 9.6 1.4 0.0 12.6 5.9 20.5 3.2 14.6 128.9 24.4 8.2 15.5 8.5 27.3 55.7 13.9 11.2 17.9 10.0 8.3 16.5 104.3 10.5 95.5 7.3 7.9 8.0 5.4 18.2 15.7 15.0 9.1 35.4 224.3 7.3 11.8 11.3 16.8 15.8 11.4 47.9 15.0 11.0 4.0 161.5 187.5 9.9 12.2 8.6 7.6 8.8 17.4 9.0 8.8 38.4 11.8 24.9 247.2 200.6 113.6 6.3 9.6 14.3 30.1 12.7 10.6 13.6 8.8 79.8 0.0 25.5 9.0 31.4 26.4 12.8 6.7 3.7 79.4 23.3 11.5 9.5 PTPRB PTPB ENSG00000127329 "Protein tyrosine phosphatase receptor type B" P23467 12 70515870-70637440 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 215.9;Endothelial cells: 211.5;Hepatic stellate cells: 504.0;Microglial cells: 164.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 24.3;hTERT-RPE1: 19.7;HUVEC TERT2: 61.4;TIME: 90.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004782, HPA067868" Uncertain Approved "Vesicles,Plasma membrane,Cell Junctions" NA NA 14000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Vesicles, Cell Junctions" "CAB004782: , HPA067868: AB_2685911" "unprognostic (3.18e-1)" "unprognostic (2.99e-6)" "unprognostic (1.56e-1)" "unprognostic (1.80e-1)" "unprognostic (3.55e-2)" "unprognostic (1.77e-2)" "prognostic favorable (6.05e-4)" "unprognostic (4.59e-1)" "unprognostic (2.22e-2)" "unprognostic (1.85e-1)" "unprognostic (2.28e-2)" "unprognostic (1.40e-1)" "prognostic favorable (1.02e-4)" "unprognostic (2.91e-2)" "unprognostic (7.18e-2)" "unprognostic (1.31e-1)" "unprognostic (1.38e-1)" 26.7 9.4 16.0 4.7 14.1 0.1 18.8 12.3 12.1 12.8 7.1 10.9 7.5 12.3 4.4 6.8 10.8 14.7 23.2 10.1 12.4 22.5 16.7 35.7 3.2 15.9 14.2 4.0 6.2 7.8 4.7 32.6 18.1 6.3 11.1 1.4 3.3 8.0 17.1 4.1 9.3 18.1 12.4 30.0 6.2 2.5 19.0 3.0 14.8 38.8 3.4 7.7 5.3 11.9 4.4 0.3 1.9 0.2 0.0 0.1 0.9 0.9 4.2 2.2 5.2 0.1 3.4 1.7 24.3 0.6 0.4 15.2 0.2 0.7 7.8 1.3 0.7 0.4 1.7 1.1 0.2 0.7 0.0 0.1 0.7 6.1 0.0 19.7 61.4 0.0 3.6 1.0 1.3 0.0 0.1 0.0 2.3 4.4 0.9 0.1 1.6 0.9 11.3 1.8 0.0 0.8 1.6 0.0 3.5 0.4 0.0 1.5 90.3 0.9 0.9 0.4 5.4 1.1 0.9 0.8 0.4 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 16.0 14.1 12.3 12.1 10.1 12.4 15.9 14.2 18.1 12.4 19.0 11.9 215.9 0.0 13.2 2.0 3.1 3.7 0.8 1.0 0.0 7.1 0.9 0.9 12.3 11.5 1.3 3.7 0.0 0.0 2.0 12.8 0.0 1.5 4.6 2.2 0.7 211.5 0.0 16.0 52.5 0.9 0.0 7.3 1.5 4.0 25.2 0.5 504.0 4.7 0.4 5.0 68.8 6.4 0.0 20.0 4.6 3.0 1.2 1.2 5.4 164.9 0.0 0.4 0.0 2.5 2.9 12.2 11.1 0.0 0.1 0.8 3.2 0.1 0.2 0.9 0.0 6.4 5.2 0.7 0.7 0.9 1.6 0.0 1.0 1.8 6.8 0.7 PTPRJ "CD148, DEP1, HPTPeta" ENSG00000149177 "Protein tyrosine phosphatase receptor type J" Q12913 11 47980558-48170841 "CD markers, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 167.5;Microglial cells: 189.3;Oligodendrocyte precursor cells: 239.8;Oligodendrocytes: 167.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 9.5" "Group enriched" "Detected in many" 4 "granulocytes: 9.5;monocytes: 4.7" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 52.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006026 Approved "Intracellular and membrane" NA NA 670000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 68: Oligodendrocytes - Mixed function" "HPA006026: AB_1078446" "unprognostic (1.46e-1)" "unprognostic (2.21e-1)" "unprognostic (1.55e-1)" "unprognostic (3.83e-2)" "unprognostic (3.20e-2)" "unprognostic (2.99e-2)" "unprognostic (6.58e-2)" "unprognostic (2.15e-1)" "unprognostic (9.64e-3)" "unprognostic (3.79e-3)" "unprognostic (5.16e-2)" "unprognostic (1.89e-1)" "prognostic favorable (1.13e-5)" "unprognostic (1.09e-2)" "unprognostic (7.98e-2)" "unprognostic (9.18e-2)" "unprognostic (2.00e-1)" 6.0 3.2 10.2 20.5 13.8 29.5 6.1 6.9 14.9 6.2 18.5 10.2 9.4 2.4 7.8 1.9 4.1 7.1 2.7 10.0 12.7 13.9 11.9 10.0 15.5 9.7 11.7 1.6 6.1 15.8 10.1 7.6 12.4 7.9 8.7 8.1 10.1 7.0 2.4 4.2 14.5 5.9 6.0 23.3 14.6 2.3 18.5 7.0 19.6 2.7 11.0 6.9 2.1 14.7 7.6 28.3 12.1 7.0 1.9 4.1 4.2 7.5 5.5 12.9 9.2 2.0 40.8 6.9 51.8 19.1 19.6 6.0 19.0 2.0 14.9 46.6 5.4 1.9 34.9 2.8 12.1 2.7 41.5 3.2 0.6 3.8 1.0 31.7 7.8 0.5 2.6 4.4 4.7 17.0 0.1 17.3 9.7 25.7 4.4 1.6 1.6 4.0 52.6 11.1 7.9 2.5 20.2 12.0 19.4 8.9 13.0 20.3 25.7 9.9 10.8 20.5 23.4 1.1 1.7 11.4 11.7 8.0 37.3 0.7 1.1 2.8 1.6 2.0 1.0 0.8 0.9 1.2 0.8 0.5 0.7 0.9 9.5 1.0 4.7 1.5 1.0 0.8 10.2 13.8 6.9 14.9 10.0 12.7 9.7 11.7 12.4 6.0 18.5 14.7 1.5 9.6 16.7 43.1 11.3 0.3 9.8 0.8 0.6 13.6 8.3 4.1 3.7 17.2 13.0 38.6 6.2 1.9 32.7 35.5 0.0 7.4 5.5 13.5 2.2 4.5 12.6 3.2 81.0 5.0 0.6 4.0 22.4 22.9 13.9 2.5 5.0 15.6 30.0 10.1 167.5 10.1 2.0 74.2 5.7 8.2 0.3 40.2 1.8 189.3 36.0 10.3 21.6 239.8 167.7 11.8 28.0 0.4 12.9 25.3 37.6 13.5 4.9 1.3 0.0 3.3 4.9 0.2 4.8 0.5 0.3 1.9 22.0 2.3 7.6 8.2 PTPRQ DFNB84 ENSG00000139304 "Protein tyrosine phosphatase receptor type Q" 12 80402178-80680273 "Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "kidney: 7.1;urinary bladder: 4.1" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 16.0;Club cells: 4.4;Early spermatids: 10.9;Excitatory neurons: 11.2;Late spermatids: 4.6" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 4.9;BJ: 3.9;HBF TERT88: 2.6;RH-30: 2.9;RT4: 3.4;SiHa: 1.9;U-2197: 3.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA053245 Uncertain Approved Cytosol No NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 18: U-2197 - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA053245: AB_2682087" "unprognostic (9.10e-2)" "unprognostic (1.63e-1)" "unprognostic (1.15e-1)" "unprognostic (3.30e-2)" "unprognostic (1.37e-1)" "unprognostic (1.93e-2)" "unprognostic (1.04e-2)" "unprognostic (1.46e-1)" "unprognostic (1.80e-2)" "unprognostic (1.78e-1)" "unprognostic (4.47e-11)" "unprognostic (8.51e-3)" "unprognostic (1.47e-1)" "unprognostic (1.73e-2)" "unprognostic (2.66e-2)" 3.2 0.0 0.3 0.0 2.0 0.0 0.4 0.0 0.7 0.5 0.0 0.1 0.0 0.0 1.9 0.1 1.6 0.2 1.1 0.2 0.4 7.1 0.0 2.3 0.9 1.0 0.7 0.3 0.3 0.1 0.1 0.1 0.6 0.6 0.0 0.8 0.1 0.1 0.2 0.1 0.0 0.0 0.8 0.0 0.1 2.7 0.3 0.2 2.9 0.0 0.3 4.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 4.9 0.0 3.9 0.8 1.2 0.7 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.5 0.0 0.5 0.1 0.3 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 3.4 0.0 0.0 1.9 0.0 0.0 0.1 0.2 0.0 0.0 0.3 0.1 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.0 0.0 0.7 0.2 0.4 1.0 0.7 0.6 0.8 0.3 0.0 0.0 16.0 1.1 2.0 0.0 0.0 1.9 0.3 0.0 0.1 0.0 0.0 3.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.9 0.0 0.0 0.0 0.0 0.0 11.2 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 4.6 0.0 0.1 0.0 0.0 0.0 0.9 0.0 2.5 1.3 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.5 0.2 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.7 PTPRZ1 "phosphacan, PTP18, PTPRZ, PTPZ, RPTPB" ENSG00000106278 "Protein tyrosine phosphatase receptor type Z1" P23471 7 121873089-122062036 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 88.4;skin 1: 31.9" "Cell type enriched" "Detected in many" 4 "Oligodendrocyte precursor cells: 2714.3" "Cancer enriched" "Detected in many" 14 "glioma: 175.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "AF22: 425.5;NTERA-2: 126.3;WM-115: 193.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015103 Enhanced Approved Vesicles,Cytosol "Secreted in brain" NA NA 3400000 "Cluster 27: Brain & Skin - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" Cytosol Vesicles "HPA015103: AB_1855946" "unprognostic (8.49e-4)" "unprognostic (3.96e-3)" "unprognostic (4.11e-2)" "unprognostic (1.37e-1)" "unprognostic (9.18e-2)" "unprognostic (2.41e-2)" "unprognostic (8.30e-3)" "unprognostic (3.78e-2)" "unprognostic (1.57e-1)" "unprognostic (2.53e-1)" "unprognostic (9.17e-4)" "unprognostic (1.83e-1)" "unprognostic (8.72e-6)" "unprognostic (2.00e-1)" "unprognostic (2.16e-1)" "unprognostic (8.77e-2)" "prognostic unfavorable (9.36e-4)" 1.6 1.6 66.0 1.2 64.2 0.0 4.0 57.2 88.4 1.8 21.5 4.4 0.6 0.1 0.8 7.9 0.3 0.7 1.3 64.0 64.1 0.1 0.1 1.2 0.0 60.9 62.9 0.7 2.7 0.0 2.3 0.2 62.4 1.0 1.1 19.0 3.4 0.7 0.1 31.9 1.0 1.3 63.7 1.0 13.8 0.3 58.6 0.2 0.1 0.3 2.6 0.9 2.3 72.4 0.1 0.0 425.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 12.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.1 0.0 27.7 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 126.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 5.4 15.2 0.1 0.0 0.0 0.1 0.0 0.0 0.7 10.9 5.6 0.0 0.6 0.0 193.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 66.0 64.2 57.2 88.4 64.0 64.1 60.9 62.9 62.4 63.7 58.6 72.4 0.1 0.0 1.5 625.2 0.2 25.2 8.6 82.2 44.9 18.3 5.6 12.2 1.3 0.0 39.7 0.0 4.2 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.4 0.3 0.0 0.0 37.7 0.7 0.1 1.3 9.2 0.0 0.0 10.1 0.0 0.0 0.1 65.6 72.0 0.0 0.0 0.0 1.6 0.7 0.3 0.1 19.6 22.5 0.0 90.4 0.0 2714.3 3.6 0.9 0.3 0.0 1.2 1.8 0.0 0.1 16.9 6.6 0.0 1.2 1.7 0.1 1.6 14.8 21.5 0.3 0.2 0.5 0.0 7.8 PWWP3B "FLJ33516, MUM1L1" ENSG00000157502 "PWWP domain containing 3B" Q5H9M0 X 106168305-106208956 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "ovary: 189.9" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 12.2;Cytotrophoblasts: 1.9;Endothelial cells: 1.7;Fibroblasts: 4.0;Syncytiotrophoblasts: 3.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 2.9;HHSteC: 1.6;HSkMC: 2.9;LHCN-M2: 5.5;NTERA-2: 2.1;SuSa: 1.5;T-47d: 1.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000168, HPA020464" Enhanced NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA000168: AB_1079431, HPA020464: AB_1854209" "unprognostic (2.79e-1)" "unprognostic (1.08e-2)" "unprognostic (3.83e-2)" "unprognostic (6.08e-2)" "unprognostic (5.06e-2)" "unprognostic (4.12e-6)" "unprognostic (3.48e-2)" "unprognostic (1.31e-1)" "unprognostic (3.86e-1)" "unprognostic (1.09e-1)" "unprognostic (1.88e-1)" "unprognostic (8.43e-3)" "unprognostic (2.11e-5)" "unprognostic (1.66e-1)" "prognostic unfavorable (5.95e-4)" "unprognostic (2.53e-2)" 3.5 3.7 4.5 0.0 3.8 0.0 1.0 0.1 7.4 13.7 0.2 0.1 0.0 15.8 9.3 0.3 13.5 1.2 4.3 4.5 12.2 1.4 1.5 0.5 0.0 2.6 8.1 189.9 28.1 0.7 6.1 0.5 5.5 2.4 0.1 0.1 0.2 3.5 10.9 0.2 0.1 3.1 0.5 0.0 1.2 18.0 9.1 0.0 10.3 9.2 0.0 0.3 2.2 3.1 0.0 0.0 2.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 1.6 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.9 0.0 0.0 0.4 0.0 0.0 0.0 0.7 0.0 1.5 1.9 0.0 0.0 0.2 1.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 3.8 0.1 7.4 4.5 12.2 2.6 8.1 5.5 0.5 9.1 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.2 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.4 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 PXYLP1 "ACPL2, FLJ23751" ENSG00000155893 "2-phosphoxylose phosphatase 1" Q8TE99 3 141228726-141367753 "Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 148.2" "Cell type enhanced" "Detected in many" "Early spermatids: 196.8;Late spermatids: 131.1;Spermatocytes: 95.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017243 Uncertain "Intracellular and membrane" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 68: Epididymis - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA017243: AB_1844509" "unprognostic (9.55e-2)" "unprognostic (3.48e-3)" "unprognostic (1.81e-1)" "unprognostic (2.06e-1)" "unprognostic (8.45e-2)" "unprognostic (8.04e-3)" "unprognostic (4.05e-3)" "unprognostic (5.43e-2)" "unprognostic (1.27e-1)" "unprognostic (6.95e-2)" "unprognostic (5.07e-3)" "unprognostic (4.67e-2)" "unprognostic (1.29e-2)" "unprognostic (5.20e-2)" "unprognostic (1.37e-1)" "unprognostic (8.56e-2)" "unprognostic (8.17e-3)" 4.2 6.3 5.6 4.3 6.4 5.0 8.3 1.7 13.5 7.3 0.3 5.4 5.5 8.8 148.2 2.6 6.4 8.2 13.8 6.3 6.5 7.5 5.1 4.9 9.1 1.0 3.0 8.6 9.2 16.2 7.4 18.2 1.1 10.1 5.6 18.3 6.6 28.9 2.9 4.6 6.4 7.2 3.4 5.3 5.0 8.9 3.4 53.3 5.9 2.0 9.9 7.0 4.7 6.6 5.3 5.5 23.3 18.5 9.0 7.7 5.6 3.6 9.0 9.1 12.5 9.2 1.8 0.3 4.9 8.2 1.9 1.2 24.7 2.3 8.7 17.4 16.3 1.9 7.5 7.4 19.2 4.8 1.0 7.3 10.4 2.8 1.0 11.3 0.6 17.8 0.9 2.1 4.1 4.5 25.8 6.0 9.7 13.2 3.1 3.5 13.6 3.2 6.5 22.8 10.1 17.8 9.3 2.9 7.6 4.2 9.7 2.8 1.1 11.6 6.9 8.0 3.5 4.9 0.4 0.7 10.7 6.5 10.4 15.2 6.0 9.4 13.4 4.0 8.6 0.7 7.5 8.9 5.3 0.5 21.6 17.6 3.8 19.3 2.0 1.9 4.3 8.9 5.6 6.4 1.7 13.5 6.3 6.5 1.0 3.0 1.1 3.4 3.4 6.6 1.1 9.6 8.7 14.0 2.2 0.0 4.6 0.0 6.2 3.3 9.5 6.7 7.6 2.8 1.8 46.0 6.2 2.1 3.4 2.1 0.0 3.2 196.8 1.0 9.3 1.4 4.2 4.4 41.3 3.7 8.2 7.9 1.1 1.8 2.5 5.4 1.4 3.8 0.7 6.7 31.8 3.9 0.0 1.8 0.0 131.1 20.2 2.0 0.0 1.0 3.5 8.0 3.1 32.6 6.5 3.0 8.6 15.1 2.7 7.6 4.2 11.7 2.9 5.2 13.1 6.6 4.2 95.9 13.8 2.2 0.0 1.1 4.9 0.9 4.7 6.6 PYM1 "PYM, WIBG" ENSG00000170473 "PYM homolog 1, exon junction complex associated factor" Q9BRP8 12 55901413-55932618 "Predicted intracellular proteins" "Nonsense-mediated mRNA decay, Translation regulation" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 110.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012803, HPA039717, HPA046200" Supported Supported "Nucleoplasm,Nucleoli,Cell Junctions,Cytosol" No No 27000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 43: THP-1 - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Nucleoli, Cytosol" "Cell Junctions" "CAB012803: AB_2269494, HPA039717: AB_2676644, HPA046200: AB_10965556" "unprognostic (3.03e-2)" "unprognostic (1.00e-1)" "unprognostic (5.65e-2)" "unprognostic (8.82e-2)" "unprognostic (1.97e-1)" "unprognostic (2.28e-1)" "prognostic unfavorable (3.05e-4)" "unprognostic (3.29e-1)" "unprognostic (2.17e-3)" "unprognostic (2.44e-2)" "unprognostic (3.94e-2)" "unprognostic (1.29e-1)" "unprognostic (1.32e-2)" "unprognostic (1.59e-2)" "unprognostic (2.22e-1)" "unprognostic (1.29e-1)" "prognostic favorable (1.34e-4)" 24.5 30.8 19.8 24.0 20.2 22.5 27.9 21.5 24.8 26.1 22.9 31.1 31.6 22.1 41.5 72.3 22.7 19.8 21.8 19.5 20.7 26.3 43.0 20.8 35.4 20.5 20.6 17.1 28.0 26.3 22.3 22.8 20.5 31.2 30.0 17.4 34.0 15.9 29.8 41.9 29.5 19.8 20.1 31.1 24.1 25.9 20.1 33.2 27.0 29.0 42.1 24.8 31.4 20.2 50.3 39.1 56.1 31.4 33.4 43.2 92.6 36.1 43.1 33.3 28.0 57.7 57.9 62.9 53.6 35.1 15.4 38.6 43.6 77.1 26.7 48.6 32.7 51.0 35.1 71.8 40.7 59.7 44.7 39.2 48.8 37.7 56.0 42.2 35.9 27.3 44.5 67.4 39.7 75.3 38.6 105.7 98.3 56.7 20.2 34.3 22.3 72.5 69.5 69.8 37.7 43.4 46.2 61.1 33.1 51.8 74.5 124.0 28.2 20.0 28.3 31.5 26.6 35.5 58.2 97.2 34.2 40.9 31.9 17.5 79.8 75.8 58.5 92.2 72.3 98.1 105.4 82.2 120.2 88.2 68.7 69.5 19.1 53.1 66.5 65.6 186.0 87.2 19.8 20.2 21.5 24.8 19.5 20.7 20.5 20.6 20.5 20.1 20.1 20.2 16.2 19.2 17.3 0.0 28.6 0.0 29.4 0.0 21.1 12.7 41.7 38.4 0.0 25.8 14.2 23.9 8.4 84.3 21.1 29.8 78.2 40.6 15.2 21.1 17.0 16.3 7.3 32.2 0.0 50.6 76.3 17.6 22.4 21.1 18.9 14.5 22.9 44.3 55.2 6.7 0.0 32.1 0.0 47.7 0.0 11.7 23.3 42.8 0.0 0.0 110.4 55.7 48.4 0.0 0.0 54.1 33.7 23.7 21.9 34.7 66.8 61.3 16.8 13.6 13.1 18.0 15.7 23.8 25.6 63.1 0.0 62.0 29.6 16.5 29.3 34.3 PYROXD1 "DKFZp762G094, FLJ22028" ENSG00000121350 "Pyridine nucleotide-disulphide oxidoreductase domain 1" Q8WU10 12 21437615-21471250 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Oxidoreductase "Disease variant, Limb-girdle muscular dystrophy, Myofibrillar myopathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 179.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038319, HPA038320" Uncertain Approved "Nuclear speckles" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 18: U-2197 - ECM organization" "Cluster 29: Early spermatids - Spermatogenesis" "Nuclear speckles" "HPA038319: AB_10669522, HPA038320: AB_2675956" "unprognostic (1.48e-1)" "unprognostic (1.68e-1)" "unprognostic (1.15e-2)" "unprognostic (9.89e-2)" "unprognostic (1.51e-1)" "unprognostic (2.64e-3)" "unprognostic (1.50e-1)" "unprognostic (9.31e-2)" "unprognostic (8.94e-3)" "unprognostic (1.17e-2)" "unprognostic (1.57e-1)" "unprognostic (3.32e-2)" "unprognostic (1.06e-2)" "unprognostic (3.78e-2)" "unprognostic (2.30e-2)" "unprognostic (2.00e-1)" "prognostic favorable (1.70e-4)" 7.9 10.0 3.8 9.2 4.3 9.3 10.4 5.1 5.4 7.1 5.3 11.9 13.9 7.1 8.6 8.3 7.1 8.7 10.7 3.7 5.2 16.8 12.3 8.6 10.6 5.4 5.2 6.6 13.4 10.4 5.2 5.9 5.3 9.9 11.2 14.0 11.9 5.9 12.4 10.0 16.0 6.4 4.7 7.9 12.8 5.8 4.2 7.5 15.6 9.6 8.5 7.6 6.1 5.4 9.3 3.5 5.2 5.8 3.7 6.8 11.8 14.5 6.7 5.2 4.0 4.5 8.6 10.2 6.0 11.0 4.4 11.3 5.8 11.4 5.8 12.1 5.1 11.8 9.2 5.7 17.2 17.7 12.0 11.3 13.5 3.3 14.3 6.7 7.8 11.0 5.8 4.2 10.7 5.9 8.3 24.3 8.6 8.2 6.5 1.4 11.2 11.2 16.3 9.2 1.7 13.1 6.7 12.2 27.0 7.1 14.5 20.8 11.2 6.2 5.9 13.5 13.4 6.4 4.8 12.7 25.4 13.1 7.5 1.2 0.8 0.6 1.7 1.5 1.9 1.2 2.0 2.1 0.8 0.9 1.6 1.7 0.3 1.6 2.7 1.1 1.6 0.9 3.8 4.3 5.1 5.4 3.7 5.2 5.4 5.2 5.3 4.7 4.2 5.4 12.5 12.8 28.4 12.7 18.3 6.6 10.2 10.7 8.0 21.8 15.1 10.8 11.7 27.1 13.6 27.6 25.0 15.4 22.9 40.0 23.5 24.7 179.8 26.0 13.0 9.4 20.4 13.3 14.0 33.4 14.2 10.4 19.9 21.1 25.3 8.6 8.9 21.2 16.2 8.4 17.0 21.3 12.2 21.8 5.8 32.6 10.5 18.1 5.4 17.8 15.6 14.5 17.5 13.0 34.2 41.2 25.1 6.4 19.5 12.0 39.4 43.8 28.6 28.2 13.1 15.0 13.8 49.7 18.8 14.5 7.7 19.4 20.1 10.6 20.6 14.1 QRICH1 "AB-DIP, FLJ20259, VERBRAS" ENSG00000198218 "Glutamine rich 1" Q2TAL8 3 49029707-49094363 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation, Unfolded protein response" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037677, HPA037678" Approved Enhanced Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 59: Non-specific - Transcription" Nucleoplasm "HPA037677: AB_10671883, HPA037678: AB_2675603" "unprognostic (2.38e-2)" "unprognostic (2.05e-1)" "unprognostic (8.29e-2)" "unprognostic (1.67e-1)" "unprognostic (2.41e-1)" "unprognostic (3.14e-2)" "unprognostic (2.77e-3)" "unprognostic (6.94e-2)" "unprognostic (2.82e-2)" "prognostic favorable (7.46e-4)" "unprognostic (1.12e-1)" "unprognostic (1.40e-2)" "unprognostic (2.17e-3)" "unprognostic (5.06e-2)" "unprognostic (3.84e-1)" "unprognostic (1.76e-1)" "unprognostic (1.06e-1)" 29.8 27.9 15.4 30.5 17.0 61.0 27.8 25.3 20.2 25.8 16.0 25.9 26.3 28.6 25.9 30.0 27.6 25.2 26.0 16.9 14.8 21.3 23.5 27.8 40.1 14.7 13.2 34.0 26.0 33.2 24.8 27.0 14.6 25.8 25.2 30.4 28.3 26.3 34.8 35.4 31.0 28.9 13.2 35.8 25.9 44.5 13.3 51.9 25.7 32.4 41.9 26.8 23.7 16.9 41.4 39.6 78.6 35.6 48.2 45.8 48.2 48.4 60.3 75.6 70.7 44.3 50.8 65.6 29.1 58.9 62.8 33.5 69.0 63.0 64.8 57.8 45.1 65.5 52.9 37.8 43.1 57.9 75.0 53.3 47.4 74.8 46.6 46.2 60.3 62.7 45.0 58.6 51.6 31.8 84.9 41.4 62.3 43.7 48.9 43.3 40.3 55.4 47.6 63.2 29.9 58.9 54.9 47.7 39.7 59.3 42.4 65.5 52.5 49.0 55.1 43.7 69.8 54.2 66.6 82.2 44.0 55.2 57.2 21.3 15.6 19.1 18.1 18.9 21.5 16.6 17.3 20.6 18.5 16.6 18.3 22.0 11.7 18.1 33.0 13.5 19.8 14.3 15.4 17.0 25.3 20.2 16.9 14.8 14.7 13.2 14.6 13.2 13.3 16.9 21.8 9.6 18.9 19.6 30.5 22.2 13.7 16.0 17.1 13.6 20.6 17.7 21.1 14.3 17.9 20.2 22.9 25.7 28.2 16.6 1.9 15.9 15.8 19.8 20.7 19.6 25.9 22.5 37.9 14.0 27.8 20.3 23.9 27.5 16.5 20.0 18.9 20.4 19.7 11.8 39.1 20.6 10.2 25.3 18.3 10.9 22.4 19.5 12.4 14.0 22.3 12.5 15.5 24.6 25.5 18.6 10.5 30.9 39.7 18.0 14.4 10.1 15.2 17.6 6.6 21.9 25.3 52.4 27.8 24.5 22.6 36.8 28.5 17.0 16.8 15.5 RAB3IL1 GRAB ENSG00000167994 "RAB3A interacting protein like 1" Q8TBN0 11 61897301-61920269 "Predicted intracellular proteins" "Protein transport, Transport" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 110.9;Hofbauer cells: 65.3;Late spermatids: 133.8;Leydig cells: 56.2;Peritubular cells: 45.1;Theca cells: 47.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 36.9;HHSteC: 36.9;K-562: 34.4;RPMI-8226: 44.3;U-2197: 56.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039723 Uncertain Approved "Centriolar satellite,Cytosol" NA NA "Cluster 71: Testis - DNA repair" "Cluster 18: U-2197 - ECM organization" "Cluster 34: Spermatids - Unknown function" "Centriolar satellite, Cytosol" "HPA039723: AB_10795406" "unprognostic (1.62e-1)" "unprognostic (3.59e-2)" "prognostic unfavorable (6.08e-4)" "unprognostic (1.97e-2)" "unprognostic (8.95e-2)" "unprognostic (1.30e-2)" "prognostic unfavorable (1.61e-7)" "unprognostic (7.93e-2)" "unprognostic (2.33e-1)" "unprognostic (1.11e-1)" "unprognostic (1.86e-1)" "unprognostic (3.43e-2)" "prognostic unfavorable (1.49e-4)" "unprognostic (1.42e-2)" "unprognostic (1.20e-1)" "prognostic unfavorable (3.30e-4)" "unprognostic (1.59e-3)" 29.8 9.5 10.9 7.9 11.2 13.8 22.8 10.3 13.4 38.6 12.7 13.6 4.7 30.0 4.6 6.2 24.0 11.3 20.5 10.5 10.8 16.0 6.9 11.8 6.5 12.8 11.0 37.1 5.1 7.8 9.5 15.9 11.8 10.6 2.6 3.1 12.2 5.1 7.6 15.2 9.9 9.3 11.6 28.2 9.4 41.2 14.8 9.0 15.1 10.0 2.4 19.0 20.7 12.7 6.9 13.3 0.4 7.3 26.9 19.9 1.5 5.5 13.7 8.0 5.4 1.9 1.5 0.1 10.1 8.4 36.9 3.7 9.6 0.5 1.2 0.0 2.1 12.8 5.1 7.2 36.9 0.5 0.3 10.7 6.9 3.9 9.1 1.3 0.7 7.1 34.4 0.3 4.7 12.3 0.0 0.1 4.3 1.2 14.1 0.7 1.9 44.3 0.7 0.5 0.6 4.9 3.4 2.9 25.0 2.2 2.2 1.6 0.6 29.3 13.2 56.5 2.3 0.4 2.1 0.0 5.7 15.8 12.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.9 11.2 10.3 13.4 10.5 10.8 12.8 11.0 11.8 11.6 14.8 12.7 5.5 0.0 0.0 1.6 0.8 5.1 0.9 0.0 0.6 0.5 1.3 1.9 1.9 2.8 0.6 1.8 0.0 1.3 0.1 0.1 1.9 2.2 110.9 1.9 27.8 9.6 0.0 34.5 0.4 1.0 2.0 24.3 1.1 1.8 0.0 1.1 16.1 1.4 65.3 1.7 1.3 0.0 0.0 19.9 10.2 133.8 56.2 6.8 8.8 8.4 0.0 6.5 0.0 1.0 0.7 1.1 0.0 45.1 0.0 1.6 0.0 15.9 0.0 8.2 0.0 3.4 8.2 1.7 9.1 0.2 4.0 1.4 0.6 47.6 0.2 0.2 RAD51 "BRCC5, FANCR, HsRad51, HsT16930, RAD51A, RECA" ENSG00000051180 "RAD51 recombinase" Q06609 15 40694774-40732340 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" DNA-binding "Cancer-related genes, Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 15.7;testis: 24.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 35.3;Extravillous trophoblasts: 67.2;Spermatocytes: 53.6;Spermatogonia: 24.8;Syncytiotrophoblasts: 25.3" "Cancer enhanced" "Detected in all" "testis cancer: 19.9" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB010381, HPA039310" Enhanced Supported "Nucleoli rim,Cytosol" NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoli rim" Cytosol "CAB010381: AB_2253533, HPA039310: AB_2676434" "prognostic unfavorable (7.94e-4)" "unprognostic (7.20e-3)" "unprognostic (1.22e-1)" "unprognostic (2.72e-2)" "unprognostic (8.23e-2)" "unprognostic (1.37e-1)" "prognostic unfavorable (9.33e-4)" "unprognostic (3.40e-3)" "unprognostic (2.53e-2)" "unprognostic (1.76e-1)" "unprognostic (1.41e-3)" "unprognostic (2.53e-3)" "unprognostic (0.00e+0)" "unprognostic (2.26e-2)" "unprognostic (2.34e-1)" "unprognostic (9.59e-2)" "unprognostic (1.94e-2)" 0.9 0.6 0.4 5.5 0.5 10.5 1.9 1.7 0.7 1.0 0.6 8.3 3.2 1.2 0.4 4.2 0.7 1.3 0.6 0.4 0.5 0.5 1.3 1.1 11.0 0.4 0.3 0.6 1.4 0.5 0.2 6.8 0.5 0.8 9.1 0.3 1.0 0.3 1.0 3.1 4.1 2.4 0.1 2.4 1.8 24.3 0.3 15.7 0.6 0.5 13.3 1.7 1.5 0.5 33.8 16.1 33.4 16.3 4.4 7.8 31.1 54.9 16.5 43.3 43.8 35.4 22.1 20.4 26.8 20.9 18.9 67.7 56.6 22.1 42.3 39.0 22.2 47.7 28.2 30.4 0.4 37.9 28.5 1.7 2.9 30.0 13.5 6.4 22.5 48.5 59.6 55.8 36.6 28.5 54.4 43.6 35.2 69.2 19.0 61.0 49.0 30.7 15.4 45.3 15.4 27.0 23.6 41.4 8.5 39.2 27.0 39.4 9.9 32.8 22.2 48.7 27.2 12.0 65.1 59.8 16.3 78.0 33.5 1.3 0.6 1.7 2.4 1.3 0.6 1.7 2.5 3.2 1.0 1.1 0.6 1.2 1.2 1.8 1.4 0.9 5.9 1.2 0.4 0.5 1.7 0.7 0.4 0.5 0.4 0.3 0.5 0.1 0.3 0.5 0.0 0.0 0.0 0.3 1.9 3.6 1.5 2.0 0.0 0.8 0.1 0.0 0.9 0.0 1.0 0.0 0.0 35.3 1.4 3.0 0.0 0.0 5.7 0.2 0.2 1.0 0.0 16.0 1.6 0.0 67.2 1.3 2.0 0.2 0.0 0.6 2.2 0.2 12.7 0.0 1.2 5.3 2.0 1.6 1.7 5.3 0.6 0.5 0.0 1.0 0.3 0.3 2.1 0.5 0.6 0.1 5.0 0.7 8.2 0.9 1.0 0.0 0.1 0.0 0.0 0.5 0.9 53.6 24.8 3.9 1.6 25.3 1.2 0.1 8.0 2.1 RAD51D "HsTRAD, R51H3, RAD51L3, Trad" ENSG00000185379 "RAD51 paralog D" O75771 17 35092221-35121522 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Early spermatids: 116.5;Late spermatids: 217.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (3.41e-2)" "unprognostic (3.32e-2)" "unprognostic (1.22e-1)" "prognostic favorable (5.37e-5)" "unprognostic (7.29e-2)" "unprognostic (9.59e-2)" "unprognostic (1.24e-3)" "unprognostic (1.14e-1)" "unprognostic (3.50e-2)" "unprognostic (1.73e-2)" "prognostic favorable (3.35e-6)" "unprognostic (2.34e-2)" "prognostic unfavorable (7.20e-9)" "unprognostic (7.34e-2)" "unprognostic (2.04e-1)" "unprognostic (1.73e-2)" "unprognostic (2.22e-2)" 5.7 3.9 7.3 4.2 7.8 5.0 5.4 7.1 8.9 6.5 6.6 5.5 4.5 6.3 2.8 3.9 4.8 3.8 4.4 7.7 7.3 4.9 4.3 4.6 6.0 7.4 7.6 6.6 4.9 3.7 4.1 4.8 6.8 5.0 3.7 1.8 3.5 4.6 2.8 3.3 4.6 6.0 6.8 6.5 3.9 5.7 8.0 7.9 5.8 4.7 5.9 6.0 5.2 8.2 10.0 17.4 4.4 9.0 4.1 6.7 6.1 19.1 9.8 14.2 13.4 10.4 10.9 22.4 12.5 10.8 9.3 13.5 9.8 5.8 8.3 12.4 10.8 11.2 11.6 6.6 8.5 22.3 19.7 8.6 5.8 13.5 8.9 6.8 10.5 17.8 14.7 30.7 12.1 10.8 28.0 11.2 6.3 8.8 8.2 20.9 11.1 14.3 5.4 10.2 6.7 6.7 10.3 5.2 12.1 11.1 10.7 14.7 8.6 7.0 8.5 10.5 16.0 6.0 10.7 13.2 10.2 15.5 12.4 3.5 3.6 4.0 7.9 3.5 6.0 7.2 5.0 7.1 4.0 6.7 4.7 6.0 0.7 9.2 5.1 6.5 5.1 3.9 7.3 7.8 7.1 8.9 7.7 7.3 7.4 7.6 6.8 6.8 8.0 8.2 9.1 0.0 4.8 0.0 8.5 2.3 4.7 1.6 1.8 10.4 5.6 5.6 3.3 4.3 1.5 3.7 10.4 10.8 10.9 3.2 1.9 6.4 116.5 3.3 6.6 8.7 1.2 11.1 0.0 6.8 11.0 7.0 4.6 4.0 6.3 17.7 11.4 4.7 11.0 8.4 0.0 5.0 2.0 5.7 3.1 217.6 9.6 5.8 1.8 0.0 11.0 8.0 28.8 0.0 0.0 7.0 5.7 6.8 8.7 3.7 5.3 8.5 0.8 4.2 0.0 10.7 7.8 7.9 12.6 5.4 1.4 2.9 11.1 14.0 6.3 3.0 RALGPS2 "FLJ10244, FLJ25604, KIAA0351" ENSG00000116191 "Ral GEF with PH domain and SH3 binding motif 2" Q86X27 1 178725147-178921841 "Disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Alzheimer disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 56.2;testis: 77.0" "Cell type enhanced" "Detected in many" "B-cells: 263.1;Cone photoreceptor cells: 206.4;Late spermatids: 185.9;Rod photoreceptor cells: 397.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "memory B-cell: 26.7;naive B-cell: 21.0" "Lineage enriched" "Detected in many" 11 "B-cells: 26.7" "Cell line enhanced" "Detected in many" "U-266/84: 250.4;U-698: 194.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027143, HPA028328" Enhanced Uncertain Nucleoplasm,Cytosol NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 16: U-266 - Nucleosome" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Cytosol" "HPA027143: AB_10602071, HPA028328: AB_10601889" "unprognostic (8.13e-2)" "unprognostic (1.46e-2)" "unprognostic (4.06e-3)" "unprognostic (2.71e-1)" "unprognostic (1.23e-1)" "unprognostic (1.50e-1)" "unprognostic (5.72e-2)" "unprognostic (6.63e-3)" "unprognostic (4.07e-2)" "unprognostic (1.33e-1)" "unprognostic (2.82e-2)" "unprognostic (7.77e-2)" "unprognostic (1.55e-1)" "unprognostic (3.45e-1)" "unprognostic (6.35e-2)" "unprognostic (4.37e-2)" "unprognostic (8.97e-2)" 5.5 8.5 3.5 24.0 5.0 13.2 8.1 4.9 4.6 6.5 3.3 13.4 11.5 9.4 5.4 16.3 8.0 8.1 4.6 7.1 5.8 6.7 32.0 2.8 52.4 3.0 2.4 18.3 5.7 7.8 2.9 9.2 2.6 7.3 12.1 52.5 5.4 5.5 1.4 19.6 16.4 11.8 3.4 28.3 13.7 77.0 5.5 15.2 6.8 4.8 56.2 12.6 7.6 2.1 39.9 12.7 38.7 0.4 42.3 61.6 15.2 34.0 74.8 27.1 24.3 15.1 38.3 83.7 11.2 100.8 13.5 32.2 17.2 8.6 35.4 0.1 10.3 0.0 8.7 14.6 7.1 11.1 0.4 27.5 7.5 35.1 24.6 18.8 23.7 15.3 20.6 3.1 17.8 6.3 17.0 3.5 26.5 15.3 13.4 23.5 39.9 0.7 9.3 24.9 6.0 17.2 22.2 24.5 48.4 26.3 29.3 5.6 17.9 12.4 11.8 45.4 16.4 91.8 250.4 194.3 7.2 5.7 14.2 0.8 0.1 2.4 0.3 0.1 0.3 26.7 0.2 0.1 0.4 21.0 0.7 0.2 1.3 0.4 0.1 0.8 0.0 1.1 3.5 5.0 4.9 4.6 7.1 5.8 3.0 2.4 2.6 3.4 5.5 2.1 5.4 12.8 6.9 29.4 263.1 14.8 16.3 5.4 14.8 97.4 27.9 15.1 17.5 15.7 8.7 14.7 206.4 7.5 11.6 39.5 21.5 15.2 123.0 23.3 25.6 4.9 35.9 22.7 84.0 12.0 10.1 18.7 48.9 33.0 8.8 60.3 2.9 55.2 6.3 13.5 92.3 22.5 0.0 8.5 4.8 185.9 50.1 7.3 8.8 41.2 5.1 27.8 10.3 107.5 4.0 31.0 52.4 46.6 105.2 26.0 22.7 9.7 23.9 397.3 19.7 41.5 18.6 146.6 34.8 29.1 34.1 3.3 10.3 20.7 15.6 72.0 RAMP3 ENSG00000122679 "Receptor activity modifying protein 3" O60896 7 45157791-45186302 "FDA approved drug targets, Predicted membrane proteins, Transporters" Transport Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 144.6" "Group enriched" "Detected in many" 12 "Adipocytes: 287.8;Endothelial cells: 366.0;Hepatic stellate cells: 555.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 7 "Karpas-707: 2.5" "Group enriched" "Detected in all" 4 "cerebellum: 62.2;cerebral cortex: 49.2;thalamus: 174.9;white matter: 60.0" "Low region specificity" "Detected in all" HPA075527 Supported "Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA075527: " "unprognostic (1.62e-3)" "prognostic favorable (2.89e-4)" "unprognostic (4.85e-2)" "unprognostic (6.88e-3)" "unprognostic (3.68e-2)" "unprognostic (1.44e-3)" "prognostic favorable (2.50e-6)" "unprognostic (1.14e-1)" "unprognostic (2.35e-1)" "unprognostic (3.19e-1)" "unprognostic (2.79e-2)" "unprognostic (9.49e-2)" "unprognostic (1.09e-2)" "unprognostic (1.20e-2)" "unprognostic (2.43e-1)" "unprognostic (1.91e-1)" "unprognostic (9.21e-2)" 86.9 32.6 17.7 23.0 19.7 0.2 71.7 26.9 22.7 33.5 21.3 24.4 10.2 25.9 3.9 18.9 22.8 28.7 91.3 19.2 25.8 84.1 23.9 144.6 55.0 37.3 25.7 7.4 19.7 28.1 22.3 8.6 34.2 29.7 8.6 1.1 22.1 12.9 19.3 22.8 30.0 24.4 31.6 11.4 25.7 6.3 23.5 7.3 71.9 26.9 30.3 28.5 30.5 42.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.3 17.7 19.7 26.9 22.7 19.2 25.8 37.3 25.7 34.2 31.6 23.5 42.4 287.8 0.0 1.9 0.3 3.6 16.3 0.3 0.0 2.2 0.6 5.9 2.8 8.7 1.5 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.1 20.8 0.4 7.3 366.0 0.0 13.5 3.5 0.7 0.1 10.7 0.0 0.2 0.0 0.0 555.4 7.3 0.5 0.0 0.2 0.0 0.0 31.2 19.1 6.7 1.2 1.3 26.6 5.6 0.0 0.2 0.0 0.0 6.5 0.0 0.0 1.2 1.3 0.6 0.0 0.0 0.0 0.5 0.0 2.8 4.9 0.3 0.9 0.9 14.5 0.0 1.7 1.5 0.0 0.5 RANBP1 HTF9A ENSG00000099901 "RAN binding protein 1" P43487 22 20115938-20127355 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 754.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 2431.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065868, HPA065931" Supported Enhanced Cytosol NA NA 1400000 "Cluster 26: Non-specific - Mitochondria" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 1: K-562 - Erythropoiesis" "Cluster 10: Non-specific - Unknown function" Cytosol "HPA065868: AB_2685572, HPA065931: AB_2685580" "unprognostic (1.25e-1)" "unprognostic (1.08e-1)" "unprognostic (4.43e-3)" "unprognostic (6.55e-3)" "unprognostic (4.35e-2)" "unprognostic (2.50e-2)" "prognostic unfavorable (1.58e-6)" "unprognostic (2.83e-2)" "unprognostic (2.21e-2)" "unprognostic (5.67e-3)" "unprognostic (1.54e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (1.16e-6)" "unprognostic (2.40e-2)" "unprognostic (3.95e-1)" "unprognostic (4.44e-2)" "unprognostic (7.30e-2)" 65.5 68.0 37.6 63.3 38.6 117.5 60.7 40.2 47.9 67.1 28.8 63.9 52.9 66.7 21.4 94.7 61.2 30.0 47.5 39.7 40.5 64.8 86.7 53.5 94.7 41.1 39.1 61.0 54.0 35.9 50.3 46.2 41.4 49.8 42.9 35.3 51.8 34.3 54.9 61.8 60.6 36.2 40.8 71.1 55.5 117.8 39.6 104.0 46.5 34.8 72.6 61.9 64.7 43.7 434.6 218.5 479.7 263.2 79.1 93.8 403.7 388.7 169.3 494.6 356.4 401.5 150.8 669.8 169.7 157.8 224.9 394.2 449.4 340.4 269.6 290.1 1071.3 562.6 218.5 426.6 120.3 913.7 294.4 103.9 158.7 393.0 139.2 114.3 227.1 300.2 2431.9 261.1 226.8 339.2 665.5 622.0 547.2 553.8 380.8 667.4 674.7 172.6 171.6 233.9 478.6 354.7 356.6 196.4 236.6 210.3 137.1 378.9 176.4 341.5 668.1 258.7 438.3 260.9 383.6 1066.0 186.9 405.9 292.7 21.1 94.7 75.8 71.3 101.6 78.8 123.1 101.6 91.1 111.5 119.1 101.8 77.0 9.5 90.8 93.6 103.6 115.4 102.5 37.6 38.6 40.2 47.9 39.7 40.5 41.1 39.1 41.4 40.8 39.6 43.7 133.1 35.3 37.1 14.7 135.0 274.4 195.0 260.6 109.3 44.4 142.3 175.6 47.1 104.4 104.8 90.1 6.2 409.2 103.8 106.4 277.8 188.5 394.2 104.6 131.1 143.5 117.6 259.2 22.2 112.3 754.9 156.7 72.4 86.7 64.7 187.2 93.5 169.5 268.7 37.0 21.4 194.0 209.5 85.5 223.3 236.1 145.1 95.3 177.9 6.5 140.6 103.5 87.6 7.5 23.9 150.0 109.3 136.9 179.6 338.0 107.3 213.7 93.8 39.0 98.6 110.9 289.5 505.1 435.2 220.1 294.9 194.7 119.2 176.5 273.6 218.2 RANBP17 ENSG00000204764 "RAN binding protein 17" Q9H2T7 5 170861870-171300015 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.3" "Cell type enhanced" "Detected in many" "Early spermatids: 112.7;Excitatory neurons: 100.6;Glandular and luminal cells: 59.5;Inhibitory neurons: 152.9;Oligodendrocyte precursor cells: 65.4;Oligodendrocytes: 87.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 4.0;SK-BR-3: 3.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029568, HPA029569" Uncertain Approved "Nucleoplasm,Nuclear membrane,Nuclear bodies,Cytosol" Yes No "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Nuclear bodies" "Nuclear membrane, Cytosol" "HPA029568: AB_10599825, HPA029569: AB_10601571" "unprognostic (4.63e-2)" "unprognostic (2.63e-3)" "unprognostic (1.06e-1)" "unprognostic (8.28e-2)" "unprognostic (1.75e-3)" "unprognostic (5.12e-3)" "unprognostic (1.50e-1)" "unprognostic (2.45e-1)" "unprognostic (1.31e-1)" "unprognostic (2.00e-1)" "unprognostic (1.54e-1)" "unprognostic (9.59e-2)" "unprognostic (1.64e-2)" "unprognostic (2.19e-3)" "unprognostic (2.72e-1)" "unprognostic (1.35e-1)" "unprognostic (2.56e-3)" 0.2 0.8 0.3 0.1 0.2 0.1 0.2 2.3 0.6 0.2 0.8 0.2 0.2 0.5 0.2 0.0 0.4 0.5 0.2 0.1 1.1 0.4 0.3 0.8 0.3 0.9 0.9 0.2 1.4 0.8 0.4 0.8 1.3 0.4 0.4 0.8 0.8 0.5 0.0 0.1 0.3 0.3 0.6 0.0 0.3 1.4 0.6 0.2 1.0 0.0 0.1 0.1 0.1 1.1 0.0 0.7 4.0 3.3 1.3 0.3 2.4 2.6 1.2 1.8 1.1 1.5 0.0 0.1 2.0 2.5 0.0 0.0 0.0 1.2 3.5 0.0 2.4 0.7 1.4 0.0 1.1 0.0 0.0 2.6 0.2 0.2 0.0 0.2 1.7 0.0 0.3 0.0 1.0 1.7 0.0 0.0 0.3 0.6 0.2 0.0 2.4 0.0 0.6 1.0 0.2 1.4 0.0 3.9 1.5 1.7 0.7 1.2 2.4 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 2.3 0.6 0.1 1.1 0.9 0.9 1.3 0.6 0.6 1.1 9.4 9.6 2.0 12.7 0.0 0.3 6.2 5.8 1.8 24.8 6.1 2.8 1.3 7.2 4.8 0.0 14.6 10.4 1.7 2.3 0.0 7.3 112.7 22.4 17.5 7.9 5.4 5.5 100.6 1.4 3.2 4.9 5.1 59.5 0.0 15.6 4.2 1.6 1.9 0.0 152.9 3.7 2.0 0.6 1.4 46.5 2.8 1.0 1.8 9.4 1.2 5.5 5.2 65.4 87.1 5.3 2.9 3.0 0.8 13.0 3.9 0.9 2.4 26.9 0.0 3.0 5.1 27.2 26.7 1.4 0.0 2.5 0.8 7.5 6.3 7.6 RANBP3 ENSG00000031823 "RAN binding protein 3" Q9H6Z4 19 5916139-5978142 "Cancer-related genes, Predicted intracellular proteins" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 86.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043375, HPA043389" Enhanced Enhanced Nucleoplasm NA NA 17000 "Cluster 24: B-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "HPA043375: AB_10959889, HPA043389: AB_10963696" "unprognostic (1.81e-1)" "unprognostic (1.18e-3)" "unprognostic (3.61e-1)" "prognostic favorable (1.22e-5)" "unprognostic (4.24e-2)" "unprognostic (1.42e-3)" "unprognostic (5.44e-2)" "unprognostic (3.90e-2)" "unprognostic (3.58e-1)" "unprognostic (1.08e-1)" "prognostic favorable (4.14e-4)" "unprognostic (2.27e-1)" "unprognostic (3.80e-2)" "unprognostic (2.91e-1)" "unprognostic (5.15e-2)" "prognostic favorable (8.14e-4)" "unprognostic (1.06e-2)" 25.1 40.3 30.0 24.0 30.6 21.5 24.7 30.4 33.7 30.5 25.0 43.1 22.2 35.1 10.6 26.6 29.0 17.8 35.3 30.0 30.3 24.6 24.4 25.2 26.5 33.0 34.9 28.2 29.6 20.7 32.0 16.7 31.7 32.2 12.1 19.3 25.6 22.9 36.6 29.2 27.6 19.0 30.5 30.1 32.0 44.7 31.5 26.2 25.8 21.3 17.9 36.6 27.9 31.1 73.8 50.4 42.3 47.6 31.2 31.3 30.0 45.9 43.1 52.7 56.7 64.9 25.4 69.0 50.4 35.8 33.1 44.8 38.2 44.8 32.0 71.0 62.3 37.1 38.8 77.6 33.7 54.9 52.2 30.9 30.4 33.0 37.3 24.5 38.9 37.0 68.4 63.6 30.3 30.7 91.8 26.6 77.6 31.8 64.3 67.0 40.6 63.3 34.3 56.3 46.4 52.1 41.1 42.9 41.1 24.7 32.7 41.0 40.6 44.2 32.2 78.2 68.4 65.4 72.1 59.2 55.9 68.0 55.6 14.5 23.1 29.2 23.2 23.2 24.1 17.6 22.7 23.5 23.4 24.5 19.5 25.8 26.0 17.9 24.3 22.3 32.1 24.5 30.0 30.6 30.4 33.7 30.0 30.3 33.0 34.9 31.7 30.5 31.5 31.1 14.0 25.6 26.6 9.8 18.4 12.2 20.5 27.1 9.6 16.7 12.0 10.2 16.4 18.6 19.9 7.3 25.0 29.2 18.6 16.9 43.0 28.8 59.5 14.3 12.6 19.2 13.2 8.6 9.4 20.8 29.5 17.1 17.3 15.4 17.7 14.1 9.3 10.8 25.0 23.5 11.7 20.2 32.6 14.9 16.8 73.3 16.8 16.5 21.4 8.4 31.5 21.9 25.7 13.6 17.5 22.7 11.4 24.8 21.7 18.8 20.2 21.0 21.4 20.8 19.7 13.5 15.8 86.8 40.8 10.4 11.8 35.4 20.6 19.1 15.1 23.0 RANBP3L FLJ25422 ENSG00000164188 "RAN binding protein 3 like" Q86VV4 5 36246913-36302114 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 29.9;kidney: 24.6" "Cell type enriched" "Detected in some" 7 "Astrocytes: 355.9" "Group enriched" "Detected in some" 5 "breast cancer: 1.4;glioma: 3.7;prostate cancer: 4.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "ASC diff: 12.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA037471, HPA037472, HPA061526" Approved Uncertain Nucleoplasm NA NA "Cluster 65: Brain - Ion transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "HPA037471: AB_10671756, HPA037472: AB_2675489, HPA061526: AB_2684552" "unprognostic (1.19e-1)" "unprognostic (1.02e-1)" "unprognostic (1.27e-1)" "unprognostic (1.41e-3)" "unprognostic (5.52e-3)" "unprognostic (2.85e-1)" "unprognostic (2.35e-3)" "unprognostic (1.08e-2)" "unprognostic (9.56e-2)" "unprognostic (2.66e-1)" "unprognostic (2.81e-1)" "unprognostic (1.28e-1)" "unprognostic (3.76e-4)" "unprognostic (1.68e-2)" "unprognostic (9.13e-2)" "unprognostic (8.87e-3)" "unprognostic (5.71e-2)" 3.8 1.7 25.2 0.3 27.0 0.0 7.6 4.6 29.9 1.2 5.4 0.8 0.2 0.7 1.8 0.5 1.2 1.8 1.5 25.1 12.2 24.6 9.9 2.0 0.2 9.9 18.9 2.1 0.4 0.2 2.9 5.0 7.4 13.5 0.4 5.3 0.6 2.9 0.4 0.4 0.4 0.6 12.6 0.2 1.8 4.7 18.6 0.1 2.2 2.9 0.6 6.9 0.8 15.2 0.0 0.0 0.1 0.2 12.1 0.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.1 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 2.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.1 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.2 27.0 4.6 29.9 25.1 12.2 9.9 18.9 7.4 12.6 18.6 15.2 0.3 0.0 0.0 355.9 0.0 0.0 0.1 0.0 0.6 0.4 4.1 2.3 0.3 0.0 0.0 9.2 0.0 0.0 1.3 0.0 46.9 0.0 0.1 0.1 0.7 0.4 0.0 0.0 5.1 0.0 0.0 1.5 0.0 0.0 0.0 0.2 0.4 1.3 1.9 0.0 4.5 0.0 0.0 0.0 0.3 0.8 2.1 0.2 1.8 23.4 0.0 16.1 0.0 5.5 2.8 0.0 0.0 2.2 0.0 1.3 0.0 0.2 0.0 0.6 13.1 0.6 8.3 0.0 0.1 0.0 0.0 0.1 0.0 3.0 0.0 0.1 RAPH1 "ALS2CR18, ALS2CR9, KIAA1681" ENSG00000173166 "Ras association (RalGDS/AF-6) and pleckstrin homology domains 1" Q70E73 2 203394345-203535335 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 61.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 84.0;Hepatic stellate cells: 103.5;Microglial cells: 92.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016744, HPA020027" Approved Approved "Nuclear bodies,Plasma membrane,Cytosol" NA NA 69000000 "Cluster 7: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 44: Endometrium - Transcription" "Nuclear bodies, Plasma membrane" Cytosol "HPA016744: AB_1844781, HPA020027: AB_1844782" "unprognostic (9.78e-2)" "unprognostic (9.05e-2)" "unprognostic (7.17e-4)" "unprognostic (1.04e-1)" "unprognostic (1.58e-1)" "unprognostic (1.83e-1)" "unprognostic (8.32e-2)" "unprognostic (6.31e-2)" "unprognostic (1.39e-1)" "unprognostic (1.31e-1)" "unprognostic (1.24e-4)" "unprognostic (1.92e-1)" "unprognostic (1.40e-2)" "unprognostic (5.11e-2)" "unprognostic (2.30e-1)" "unprognostic (1.19e-2)" "unprognostic (2.79e-1)" 11.1 6.5 1.5 5.2 4.6 3.1 13.3 1.3 7.9 9.4 0.3 7.0 7.8 5.6 4.6 8.8 5.1 8.9 5.9 5.0 8.5 7.2 61.6 14.3 3.7 2.4 7.0 2.0 6.4 5.6 3.6 13.0 4.1 6.6 7.3 7.3 8.6 4.3 6.6 8.9 7.9 7.8 0.1 16.9 8.8 9.4 2.7 2.6 30.0 6.2 4.9 7.7 6.6 2.2 11.1 7.5 15.6 9.0 12.0 15.4 14.7 15.1 11.0 15.3 19.1 35.0 11.4 0.0 3.7 23.1 11.2 5.8 8.2 12.9 31.7 2.2 4.6 0.0 17.9 6.2 30.0 0.1 0.2 21.5 10.7 28.1 29.4 16.8 24.2 1.7 0.8 8.2 31.0 6.2 0.1 0.0 9.2 5.7 10.0 0.2 22.0 6.9 11.2 34.9 5.5 7.5 10.3 9.8 12.5 20.4 5.5 0.5 29.0 37.5 12.5 18.2 16.1 3.8 7.7 0.1 30.9 0.2 8.4 0.0 0.2 0.0 0.0 0.7 0.1 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.7 0.0 0.1 0.0 1.5 4.6 1.3 7.9 5.0 8.5 2.4 7.0 4.1 0.1 2.7 2.2 36.3 16.0 8.4 12.7 1.2 49.1 20.7 10.3 16.5 11.3 21.6 9.4 1.1 15.7 9.7 14.7 14.6 8.9 0.8 32.9 7.9 6.3 14.4 24.4 17.7 29.0 2.4 3.2 84.0 9.3 7.6 23.4 47.9 65.7 1.3 6.2 103.5 79.6 18.1 10.1 56.7 8.6 4.1 17.8 51.1 4.9 4.7 28.8 12.4 92.8 3.3 18.6 0.0 41.2 9.1 20.5 21.3 4.9 0.1 19.0 22.4 2.8 5.2 4.4 19.7 26.8 33.4 29.3 19.6 26.9 40.9 10.9 2.8 0.9 13.3 28.4 RASSF10 ENSG00000189431 "Ras association domain family member 10" A6NK89 11 13009316-13012119 "Predicted intracellular proteins" Neurogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 6.0;skin 1: 6.6" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 64.3;Distal tubular cells: 25.4;Gastric mucus-secreting cells: 17.9;Squamous epithelial cells: 60.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "A549: 8.9;CAPAN-2: 7.8;HaCaT: 12.6;HMC-1: 6.2;RPTEC TERT1: 11.9" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA040406 Approved Vesicles,Cytosol NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" Vesicles Cytosol "HPA040406: AB_2732485" "unprognostic (6.71e-2)" "unprognostic (5.12e-2)" "unprognostic (5.06e-2)" "unprognostic (2.41e-3)" "unprognostic (6.25e-3)" "prognostic favorable (2.76e-4)" "unprognostic (3.43e-3)" "unprognostic (8.04e-2)" "unprognostic (5.89e-2)" "unprognostic (2.10e-1)" "unprognostic (1.56e-1)" "prognostic favorable (4.12e-5)" "unprognostic (4.45e-2)" "unprognostic (1.73e-1)" "unprognostic (2.88e-1)" "unprognostic (1.65e-2)" 0.3 0.0 0.4 0.0 0.8 0.0 1.3 0.2 0.5 0.6 0.3 0.4 1.2 0.1 0.1 6.0 3.0 0.3 0.3 0.2 0.3 3.4 0.0 1.2 0.0 0.7 1.0 0.0 0.0 2.1 0.1 0.0 0.7 0.6 0.4 0.0 4.6 0.2 0.7 6.6 0.5 0.0 1.0 0.0 3.6 0.5 0.1 0.5 0.1 0.2 0.5 1.1 1.5 0.5 0.4 8.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 7.8 0.0 0.5 0.0 0.3 12.6 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 6.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.8 2.2 0.0 1.3 0.0 0.0 11.9 1.3 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.8 0.2 0.5 0.2 0.3 0.7 1.0 0.7 1.0 0.1 0.5 2.0 0.0 5.1 0.7 0.1 0.0 6.3 0.0 64.3 0.0 5.8 8.0 0.9 0.0 2.5 1.8 0.0 0.2 0.0 0.9 25.4 0.6 0.0 6.0 1.1 1.4 2.4 0.0 0.0 0.2 0.0 0.2 17.9 11.1 1.3 0.0 3.9 0.0 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.3 0.3 0.5 0.0 1.9 0.0 0.9 0.0 0.0 0.0 11.5 1.2 0.0 0.0 1.9 0.0 4.5 7.3 0.0 0.0 0.5 0.3 0.0 0.8 60.0 0.0 0.0 0.2 0.0 5.5 3.5 RASSF3 ENSG00000153179 "Ras association domain family member 3" Q86WH2 12 64507001-64697564 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 149.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 6 "neutrophil: 124.1" "Lineage enriched" "Detected in all" 6 "granulocytes: 124.1" "Cell line enhanced" "Detected in all" "SK-MEL-30: 145.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022664, CAB034035, HPA038469" Supported Supported "Plasma membrane,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 41: Macrophages - Immune response" "Plasma membrane, Cytosol" "CAB022664: , CAB034035: AB_2176848, HPA038469: AB_10671743" "unprognostic (1.63e-1)" "unprognostic (1.33e-1)" "unprognostic (1.35e-1)" "unprognostic (1.47e-1)" "unprognostic (1.55e-1)" "unprognostic (2.37e-2)" "unprognostic (2.55e-3)" "unprognostic (3.73e-1)" "unprognostic (2.37e-1)" "unprognostic (6.21e-2)" "unprognostic (3.66e-2)" "unprognostic (1.49e-1)" "unprognostic (1.45e-3)" "unprognostic (7.16e-2)" "unprognostic (2.01e-1)" "unprognostic (6.98e-2)" "unprognostic (1.59e-2)" 33.1 22.9 13.8 43.3 9.3 17.3 14.9 7.1 9.5 19.4 33.0 106.6 21.1 23.9 15.1 36.8 13.2 29.3 44.3 7.6 9.2 6.9 10.9 32.5 37.0 11.4 20.5 19.6 13.1 3.3 4.6 39.6 13.6 33.0 42.0 1.5 35.6 48.7 45.0 6.8 26.3 60.1 11.4 47.6 34.5 13.5 22.1 15.4 6.5 13.1 33.2 50.3 14.1 13.4 28.1 30.9 9.6 18.6 10.2 14.7 58.3 11.9 61.8 15.8 18.6 22.3 28.9 43.6 24.8 8.6 19.0 12.1 29.6 12.5 19.0 35.5 11.3 28.6 13.0 25.5 27.9 30.5 19.3 10.0 10.7 36.2 26.7 46.1 68.0 20.7 15.4 21.0 18.7 26.5 20.2 19.9 21.4 65.8 18.8 32.5 30.9 18.4 20.8 33.6 21.7 22.7 20.0 3.8 145.5 23.0 17.3 19.0 98.7 12.8 15.6 13.5 13.1 19.5 22.0 28.0 15.4 26.2 37.8 19.6 16.6 12.5 13.2 17.7 11.1 14.1 19.4 14.9 9.1 10.1 19.1 20.3 124.1 12.0 17.7 8.4 22.1 2.8 13.8 9.3 7.1 9.5 7.6 9.2 11.4 20.5 13.6 11.4 22.1 13.4 30.7 3.2 15.4 4.2 32.7 16.3 15.0 5.5 2.8 0.0 12.4 13.7 56.5 30.0 8.9 5.5 0.0 35.5 39.0 67.4 0.0 12.4 0.3 14.4 4.1 31.2 26.4 16.4 8.7 21.2 19.1 14.5 20.9 28.3 6.3 4.7 20.7 4.6 24.1 0.0 16.2 15.8 2.0 69.9 149.3 0.8 2.5 55.7 48.0 49.6 72.7 2.8 32.0 3.5 4.8 24.0 14.5 14.3 9.8 25.5 13.3 1.7 3.9 0.2 13.1 9.2 27.0 0.6 19.3 5.9 11.9 19.7 30.7 1.6 20.7 21.1 RAVER2 "FLJ10770, KIAA1579" ENSG00000162437 "Ribonucleoprotein, PTB binding 2" Q9HCJ3 1 64745095-64833232 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 72.8;Distal enterocytes: 60.1;Inhibitory neurons: 40.4;Oligodendrocyte precursor cells: 40.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 12 "basophil: 6.2" "Lineage enriched" "Detected in single" 12 "granulocytes: 6.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045785 Approved Approved Nucleoplasm NA NA "Cluster 38: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA045785: AB_10964058" "unprognostic (8.02e-2)" "unprognostic (5.23e-2)" "unprognostic (4.23e-3)" "unprognostic (2.73e-1)" "unprognostic (2.32e-1)" "unprognostic (2.89e-2)" "unprognostic (2.22e-3)" "unprognostic (1.23e-2)" "unprognostic (3.14e-1)" "unprognostic (1.47e-1)" "unprognostic (6.56e-2)" "unprognostic (1.09e-1)" "prognostic favorable (5.14e-6)" "unprognostic (1.74e-1)" "unprognostic (3.50e-2)" "unprognostic (1.41e-1)" "unprognostic (5.09e-2)" 4.7 8.2 12.8 4.2 12.1 9.5 8.2 15.0 12.4 7.7 12.6 23.6 24.2 7.8 5.7 9.4 7.5 11.3 12.6 13.3 10.9 7.7 1.6 8.3 2.0 9.7 12.2 6.4 7.3 16.2 12.3 7.3 10.3 12.0 26.8 15.1 15.5 10.3 22.2 6.7 26.1 9.3 10.4 4.3 12.5 2.7 13.3 8.3 6.1 17.7 4.1 6.5 7.4 9.3 16.7 5.1 15.2 16.7 2.7 2.3 4.1 3.6 6.5 7.3 8.2 13.6 7.3 0.1 8.2 3.8 16.6 12.4 15.7 10.9 8.9 0.1 17.3 20.2 13.7 12.2 5.1 27.5 0.2 6.8 9.8 0.5 7.5 16.9 12.2 16.6 4.5 16.3 0.6 6.2 9.2 5.6 18.8 13.1 13.3 31.1 23.9 6.7 8.0 12.3 11.5 25.6 16.4 0.0 16.0 14.3 12.6 4.3 4.6 6.8 10.9 6.8 13.1 12.3 14.9 7.0 4.1 0.1 6.4 6.2 0.0 0.0 0.1 0.0 0.2 0.1 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 12.8 12.1 15.0 12.4 13.3 10.9 9.7 12.2 10.3 10.4 13.3 9.3 9.2 6.4 13.5 72.8 0.6 8.0 7.0 3.9 8.0 7.1 7.2 6.0 24.4 11.5 8.3 1.8 14.6 0.2 1.1 60.1 0.0 3.4 9.8 5.7 2.5 10.6 18.0 4.2 29.0 5.2 0.3 6.3 11.2 6.5 1.3 7.1 6.8 0.3 0.6 0.0 40.4 30.7 4.1 4.8 3.3 16.8 6.5 2.0 3.6 22.5 0.3 26.1 0.0 40.2 1.8 2.7 20.5 8.2 2.3 6.6 26.9 2.1 6.1 3.7 0.0 6.2 5.5 3.1 3.2 8.5 5.8 0.3 1.5 1.7 27.8 7.3 RB1CC1 "ATG17, Cc1, DRAGOU14, FIP200, KIAA0203, PPP1R131" ENSG00000023287 "RB1 inducible coiled-coil 1" Q8TDY2 8 52622458-52745843 "Predicted intracellular proteins" "Autophagy, Cell cycle, Transcription, Transcription regulation" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024391, HPA053049" Approved Supported "Nuclear membrane,Cytosol" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" Cytosol "Nuclear membrane" "HPA024391: AB_2671554, HPA053049: AB_2682025" "unprognostic (1.58e-2)" "unprognostic (7.51e-2)" "unprognostic (9.49e-2)" "prognostic unfavorable (1.61e-4)" "unprognostic (3.22e-1)" "unprognostic (4.21e-2)" "unprognostic (7.39e-2)" "unprognostic (1.38e-2)" "unprognostic (9.34e-2)" "unprognostic (1.21e-1)" "unprognostic (8.77e-3)" "unprognostic (2.07e-1)" "unprognostic (9.56e-3)" "unprognostic (7.67e-2)" "unprognostic (4.41e-1)" "unprognostic (8.00e-2)" "unprognostic (2.42e-1)" 17.6 15.0 37.2 11.8 30.4 52.3 17.0 26.5 40.2 15.2 16.4 13.7 12.9 17.4 13.0 16.9 12.1 13.8 24.1 27.2 23.9 17.1 21.5 14.9 13.3 29.9 25.6 20.1 16.8 22.2 8.0 15.5 24.1 15.5 11.3 20.3 16.2 12.2 38.9 15.0 14.2 15.0 23.0 14.3 14.5 34.7 33.1 22.2 17.7 32.1 12.9 14.3 11.1 43.5 23.8 20.8 25.2 22.1 27.4 31.0 14.4 17.7 36.1 18.4 22.8 14.6 26.3 17.4 29.0 26.2 46.4 31.0 31.4 16.5 34.5 13.1 27.4 29.7 20.8 20.2 33.7 10.7 16.0 29.1 33.4 18.3 49.6 38.2 25.2 26.8 35.8 27.4 22.6 15.6 27.2 15.7 24.9 22.4 10.3 13.7 12.1 17.7 16.9 18.5 24.0 25.0 18.4 20.9 39.8 29.3 23.8 19.3 29.9 17.5 24.2 27.8 15.7 26.8 24.8 17.0 27.6 18.2 20.0 47.9 12.9 24.6 11.6 12.2 11.8 12.3 9.7 11.9 12.6 9.5 11.9 11.0 40.3 14.2 17.1 6.3 14.1 11.9 37.2 30.4 26.5 40.2 27.2 23.9 29.9 25.6 24.1 23.0 33.1 43.5 83.8 195.5 121.7 73.8 66.3 88.3 60.2 32.0 51.2 82.0 45.5 39.5 163.8 20.0 57.4 18.4 68.8 27.0 74.2 45.4 9.8 52.4 61.9 103.6 112.7 66.0 44.2 117.7 104.0 49.3 26.3 78.2 36.2 143.5 25.9 78.1 36.8 44.5 23.6 87.5 123.2 31.9 30.5 44.5 41.4 49.8 77.3 60.5 42.7 76.8 67.6 33.0 64.9 106.1 104.2 63.5 43.3 73.4 86.1 99.0 47.2 27.0 115.3 57.3 46.0 132.2 76.9 238.8 132.7 59.4 91.9 60.5 66.2 68.6 27.7 88.2 RBBP5 "RBQ3, SWD1" ENSG00000117222 "RB binding protein 5, histone lysine methyltransferase complex subunit" Q15291 1 205086142-205122015 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049042, HPA058085" Uncertain Supported Nucleoplasm,Nucleoli No No "Cluster 38: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Nucleoli" "HPA049042: AB_2680610, HPA058085: AB_2683600" "unprognostic (8.72e-2)" "unprognostic (6.35e-2)" "unprognostic (2.14e-2)" "unprognostic (1.36e-2)" "unprognostic (1.60e-1)" "unprognostic (1.17e-1)" "unprognostic (4.61e-3)" "unprognostic (1.24e-1)" "unprognostic (3.07e-2)" "unprognostic (2.88e-1)" "unprognostic (2.75e-1)" "unprognostic (4.98e-2)" "unprognostic (6.90e-2)" "unprognostic (3.78e-3)" "unprognostic (4.95e-2)" "unprognostic (1.28e-1)" "unprognostic (4.88e-2)" 6.3 8.2 4.7 7.2 5.3 9.5 7.9 6.4 6.4 7.8 2.7 7.0 7.1 8.1 7.5 7.0 7.5 6.1 6.4 5.7 5.3 12.4 11.0 6.6 11.3 3.4 3.8 9.5 8.2 9.4 6.1 6.5 3.8 6.9 8.0 9.8 7.6 6.9 8.7 8.5 6.7 7.1 4.3 9.3 6.7 6.1 4.5 13.2 9.8 9.9 12.8 7.5 5.2 6.4 16.3 16.9 16.0 19.0 21.8 12.5 17.3 15.2 12.9 19.0 18.8 17.9 19.1 25.3 11.3 11.1 15.5 18.2 26.9 10.1 22.4 21.6 14.5 21.2 16.4 14.6 14.1 26.9 16.6 10.1 12.9 17.6 15.0 12.7 15.4 17.9 41.6 25.2 16.0 15.0 26.1 11.3 26.1 14.2 27.9 22.9 33.9 31.6 13.2 11.7 25.0 20.1 21.3 22.3 19.2 19.0 24.2 14.9 11.8 15.6 16.6 23.1 20.2 12.2 18.3 30.6 13.9 16.5 24.5 22.0 4.9 7.9 8.0 6.4 8.5 7.8 7.4 8.1 5.4 6.2 7.1 8.7 11.6 8.2 8.3 6.0 8.1 3.5 4.7 5.3 6.4 6.4 5.7 5.3 3.4 3.8 3.8 4.3 4.5 6.4 14.7 19.2 12.2 11.4 31.0 26.9 9.7 5.9 15.9 14.5 18.9 14.6 7.1 8.6 13.4 22.0 29.2 9.1 25.2 15.8 9.8 12.1 7.3 13.1 14.0 13.2 12.1 23.1 19.9 11.6 10.7 13.5 9.7 21.0 13.9 25.6 17.2 21.8 10.9 16.8 15.7 14.0 10.2 15.6 25.9 3.2 12.8 17.9 19.6 8.4 15.6 12.6 15.5 14.6 21.2 13.6 9.8 16.1 25.9 13.5 14.7 28.8 13.2 18.3 19.7 21.9 14.1 10.2 20.4 14.6 33.8 10.8 27.9 12.6 15.8 13.4 RBBP8NL "C20orf151, dJ908M14.3" ENSG00000130701 "RBBP8 N-terminal like" Q8NC74 20 62410237-62427539 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 9.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 51.2;Intestinal goblet cells: 58.0;Paneth cells: 54.5;Proximal enterocytes: 157.4;Undifferentiated cells: 26.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 18.6;CACO-2: 27.5;MCF7: 11.5;SK-BR-3: 12.5" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" "unprognostic (8.99e-2)" "unprognostic (6.95e-3)" "unprognostic (2.71e-1)" "unprognostic (1.18e-1)" "unprognostic (1.86e-2)" "unprognostic (1.27e-3)" "unprognostic (2.07e-1)" "unprognostic (1.26e-1)" "unprognostic (1.38e-1)" "unprognostic (2.76e-1)" "unprognostic (2.15e-1)" "unprognostic (1.44e-1)" "unprognostic (7.65e-3)" "prognostic favorable (6.91e-4)" 0.0 0.0 0.0 0.2 0.0 0.0 1.0 0.0 0.3 1.5 0.0 1.7 4.5 0.1 0.7 9.1 0.7 0.5 0.0 0.0 0.0 0.9 0.0 0.2 0.0 0.0 0.0 0.0 2.1 1.9 2.0 0.4 0.0 3.8 0.6 0.0 4.4 1.0 0.0 4.7 4.7 0.0 0.0 0.0 2.7 2.9 0.0 0.0 3.6 0.0 0.3 1.7 3.6 0.0 1.9 0.0 0.0 0.0 0.0 0.0 18.6 0.0 0.0 0.0 0.0 27.5 2.8 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.5 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.1 0.0 4.5 0.0 0.0 0.0 12.5 0.0 0.1 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.2 0.3 1.3 0.3 0.0 0.0 3.3 2.2 2.7 7.2 1.7 1.8 0.0 6.0 0.0 51.2 0.0 0.3 13.4 1.0 0.0 0.0 9.6 0.0 0.4 0.2 5.1 0.2 2.0 1.4 0.0 0.0 0.0 0.0 0.6 0.0 0.0 58.0 2.0 0.0 0.0 7.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 54.5 0.0 0.0 0.7 157.4 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 2.1 1.4 2.6 0.1 0.0 26.2 1.0 RBFOX3 "FOX-3, HRNBP3, NeuN" ENSG00000167281 "RNA binding fox-1 homolog 3" A6NFN3 17 79089345-79516148 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 217.2;intestine: 97.4;urinary bladder: 80.5" "Group enriched" "Detected in many" 7 "Excitatory neurons: 320.4;Inhibitory neurons: 163.9;Skeletal myocytes: 124.4" "Cancer enhanced" "Detected in some" "prostate cancer: 1.1" "Group enriched" "Detected in many" 4 "cerebellum: 217.2;cerebral cortex: 118.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "A549: 16.1;NTERA-2: 14.2;SCLC-21H: 22.4;U-2 OS: 11.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030790, HPA075862, CAB078782" Enhanced Supported Supported Nucleoplasm NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "CAB078782: , HPA030790: AB_10602305, HPA075862: " "unprognostic (2.84e-1)" "unprognostic (1.88e-1)" "unprognostic (4.10e-2)" "unprognostic (9.23e-3)" "unprognostic (8.85e-2)" "unprognostic (2.34e-1)" "unprognostic (1.69e-1)" "unprognostic (1.09e-1)" "unprognostic (7.72e-2)" "unprognostic (1.50e-1)" "unprognostic (2.19e-1)" "unprognostic (1.04e-1)" "unprognostic (3.22e-15)" "unprognostic (8.92e-3)" "unprognostic (1.92e-1)" "unprognostic (1.61e-1)" "unprognostic (1.88e-1)" 0.5 0.9 11.8 0.4 29.7 0.6 0.3 217.2 118.3 3.0 0.0 97.4 1.5 39.9 3.1 9.6 3.6 0.0 0.3 23.6 0.0 0.3 0.2 0.6 0.1 12.3 1.1 1.3 0.5 0.9 7.5 0.0 13.4 22.3 2.4 3.4 0.2 24.4 0.5 0.5 9.1 9.5 0.0 0.5 4.2 7.5 0.0 0.0 0.3 0.0 0.0 80.5 8.2 40.2 0.0 16.1 0.2 0.2 0.0 0.0 0.4 0.5 0.0 0.1 0.0 0.3 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.7 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 14.2 0.0 0.2 0.3 0.7 0.1 0.0 0.0 22.4 0.4 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 11.1 0.6 0.0 0.9 0.0 0.4 0.5 0.4 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 11.8 29.7 217.2 118.3 23.6 0.0 12.3 1.1 13.4 0.0 0.0 40.2 0.5 0.0 0.0 5.9 0.2 2.0 8.1 0.0 0.0 11.5 0.2 0.0 2.3 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.0 0.0 5.7 0.3 0.4 7.5 0.0 0.0 320.4 0.0 0.1 11.8 0.0 0.7 0.0 0.1 0.0 0.2 0.1 5.0 163.9 0.0 0.0 0.6 5.5 10.1 0.3 7.6 5.4 10.3 0.0 1.2 2.1 11.1 4.8 0.0 0.0 10.5 0.0 15.2 0.0 0.1 0.0 3.1 0.0 124.4 7.5 2.4 26.4 0.0 1.4 0.1 2.3 0.1 0.0 2.8 RBM15B "HUMAGCGB, OTT3" ENSG00000259956 "RNA binding motif protein 15B" Q8NDT2 3 51391285-51397908 "Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing, Transcription, Transcription regulation" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036645, HPA058136" Approved Enhanced Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "HPA036645: AB_10671965, HPA058136: AB_2683618" "unprognostic (2.65e-3)" "unprognostic (1.31e-1)" "unprognostic (1.01e-2)" "unprognostic (1.39e-1)" "unprognostic (5.29e-1)" "unprognostic (5.28e-2)" "unprognostic (3.13e-3)" "unprognostic (1.70e-1)" "unprognostic (5.25e-2)" "unprognostic (3.11e-1)" "unprognostic (3.39e-1)" "unprognostic (3.01e-2)" "prognostic favorable (1.84e-5)" "unprognostic (1.35e-1)" "unprognostic (1.69e-1)" "unprognostic (1.89e-1)" "unprognostic (3.84e-1)" 13.0 10.3 10.2 10.6 9.5 11.1 12.3 8.8 10.5 12.0 7.4 14.4 10.4 16.9 10.6 17.0 12.0 9.3 10.4 9.9 9.5 9.7 9.9 11.5 11.2 9.9 10.1 14.6 17.8 13.8 10.7 8.0 8.9 10.9 11.9 8.2 12.3 11.0 6.1 16.5 13.0 12.2 9.3 11.4 14.6 11.4 9.7 19.7 10.8 7.0 12.2 13.0 10.5 9.6 19.2 16.7 38.2 40.1 33.7 26.2 23.3 17.4 32.2 27.2 22.3 20.8 13.6 27.5 14.1 31.5 30.0 17.3 22.0 31.3 13.1 22.2 17.3 23.9 26.2 17.9 19.7 31.4 13.0 28.6 38.2 25.0 29.5 29.6 28.5 44.3 18.1 18.2 23.6 20.4 54.8 19.8 30.5 17.6 25.9 19.4 16.8 23.5 24.5 45.5 24.7 35.5 22.4 29.5 20.6 25.2 23.4 36.7 26.0 27.7 24.1 23.6 33.3 26.6 25.9 30.3 22.6 24.8 30.2 0.0 1.9 0.7 1.8 2.7 1.9 1.0 2.2 1.9 2.1 2.4 2.2 1.3 0.4 1.7 2.7 2.3 1.1 1.6 10.2 9.5 8.8 10.5 9.9 9.5 9.9 10.1 8.9 9.3 9.7 9.6 16.7 3.2 5.4 4.2 15.2 25.4 38.9 12.6 16.5 18.2 24.9 20.2 17.3 20.0 12.5 14.7 10.4 15.2 19.8 19.9 11.7 19.4 22.4 17.6 17.2 19.1 12.6 19.0 4.4 23.2 20.7 16.7 21.4 19.6 5.1 31.0 17.9 20.5 18.4 15.2 5.1 21.0 12.2 33.1 20.9 10.6 15.8 15.1 7.2 2.8 16.3 14.2 22.6 3.5 5.0 28.2 13.4 15.1 16.4 32.8 15.2 16.5 11.2 15.5 26.3 26.0 21.1 14.9 7.9 28.0 28.1 19.7 16.3 21.0 24.4 36.7 RBM24 "dJ259A10.1, FLJ30829, RNPC6" ENSG00000112183 "RNA binding motif protein 24" Q9BX46 6 17281361-17293871 "Predicted intracellular proteins" "Differentiation, mRNA processing, mRNA splicing, Translation regulation" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "heart muscle: 142.1;skeletal muscle: 313.0;tongue: 105.7" "Cell type enriched" "Detected in many" 5 "Cardiomyocytes: 193.2" "Cancer enhanced" "Detected in many" "testis cancer: 5.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "LHCN-M2: 58.7;RH-30: 59.7;T-47d: 28.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA066927, HPA067231" Enhanced Enhanced Nucleoplasm,Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm Cytosol "HPA066927: AB_2685750, HPA067231: AB_2685808" "unprognostic (9.05e-3)" "unprognostic (2.57e-1)" "unprognostic (2.24e-1)" "unprognostic (1.67e-3)" "unprognostic (1.53e-1)" "unprognostic (4.54e-4)" "unprognostic (3.34e-2)" "unprognostic (1.33e-2)" "unprognostic (2.97e-3)" "unprognostic (3.38e-2)" "unprognostic (2.98e-2)" "unprognostic (1.43e-1)" "unprognostic (1.45e-1)" "unprognostic (1.16e-2)" "unprognostic (3.06e-2)" "unprognostic (1.08e-2)" "unprognostic (2.33e-4)" 5.4 0.5 3.7 1.7 4.1 0.1 3.7 0.1 5.7 13.9 2.5 9.7 1.6 31.2 16.8 7.4 24.0 2.6 142.1 4.5 4.9 0.9 1.1 1.3 0.5 1.6 1.9 2.1 0.2 2.1 5.5 0.6 0.7 9.9 7.4 0.4 4.1 5.8 313.0 1.4 3.6 29.3 0.6 1.2 2.1 4.2 3.0 0.8 2.1 105.7 0.3 8.8 3.6 2.2 1.5 9.3 12.0 0.0 0.0 0.0 0.0 18.7 6.8 12.4 13.0 0.0 1.1 0.0 5.7 13.4 19.5 0.0 11.5 0.4 22.3 0.0 0.4 0.0 1.0 6.4 0.5 0.0 1.1 6.4 0.0 2.4 0.5 15.8 1.6 0.0 0.0 0.0 58.7 2.8 0.0 0.2 4.1 0.0 1.4 0.1 59.7 0.0 0.0 0.0 7.8 0.9 0.2 0.0 0.2 9.3 28.2 0.4 0.0 4.2 10.0 0.0 16.2 0.0 0.0 0.1 0.3 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 4.1 0.1 5.7 4.5 4.9 1.6 1.9 0.7 0.6 3.0 2.2 1.1 0.0 0.0 0.0 0.0 1.1 0.2 1.1 0.0 2.3 3.2 0.8 193.2 0.0 1.8 0.0 0.0 0.1 0.1 4.3 0.0 0.0 0.6 33.5 13.6 1.5 4.8 0.0 11.6 0.0 13.4 6.4 0.0 9.9 1.3 0.5 0.4 0.0 0.3 1.7 6.6 4.5 0.0 0.0 0.7 1.9 0.0 0.3 1.8 1.9 0.0 0.7 0.0 0.5 0.4 0.3 2.2 0.7 0.0 0.3 0.0 0.6 21.9 0.0 6.6 23.9 19.7 0.4 7.3 0.2 1.0 0.8 0.5 0.0 3.0 0.1 RBM7 ENSG00000076053 "RNA binding motif protein 7" Q9Y580 11 114400030-114414203 "Predicted intracellular proteins" Meiosis RNA-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 196.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013993, HPA048003" Supported Enhanced Nucleoplasm NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm "HPA013993: AB_1856137, HPA048003: AB_2680231" "unprognostic (2.90e-3)" "unprognostic (8.21e-3)" "prognostic favorable (6.14e-4)" "unprognostic (1.03e-2)" "unprognostic (1.43e-1)" "unprognostic (2.58e-2)" "unprognostic (1.93e-2)" "unprognostic (2.89e-1)" "unprognostic (9.38e-3)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.17e-4)" "unprognostic (1.05e-1)" "unprognostic (3.62e-2)" "unprognostic (5.49e-2)" "unprognostic (4.74e-2)" "unprognostic (1.84e-1)" "unprognostic (8.30e-2)" 18.5 9.1 3.4 6.5 5.3 39.8 15.3 7.6 7.8 12.9 3.6 13.1 6.2 13.9 4.9 13.3 13.9 10.5 9.9 4.0 5.1 12.7 18.0 13.7 6.8 6.3 5.0 16.4 10.0 9.6 7.2 11.3 5.0 10.1 11.2 6.8 12.7 8.7 12.2 10.8 11.3 10.9 5.2 10.1 12.1 11.5 4.0 15.2 10.4 14.6 9.3 12.6 13.2 6.6 13.1 13.4 17.0 11.5 21.9 27.6 11.3 31.1 43.5 34.6 37.8 30.7 28.1 24.2 34.5 28.0 26.0 11.0 19.7 23.6 40.4 15.3 8.4 27.5 14.5 27.3 36.7 18.9 15.3 32.2 25.0 31.2 41.7 32.6 30.1 17.1 19.8 2.9 20.8 6.4 23.0 9.5 13.9 13.1 19.7 14.5 29.5 18.2 26.1 22.2 13.1 12.5 18.8 10.4 8.9 27.5 6.8 5.0 26.6 9.1 17.2 10.2 22.8 10.8 12.4 18.8 7.3 22.7 14.9 53.0 15.3 17.8 11.5 13.7 15.2 11.9 11.6 10.5 15.2 9.7 14.8 11.6 14.0 17.3 16.5 14.0 14.7 10.6 3.4 5.3 7.6 7.8 4.0 5.1 6.3 5.0 5.0 5.2 4.0 6.6 49.4 16.0 25.7 2.0 44.0 67.4 78.4 48.4 41.5 11.5 47.4 31.9 15.1 30.0 34.2 29.5 12.5 51.0 52.4 30.8 66.5 49.8 196.4 37.6 38.8 45.0 47.4 26.1 5.4 35.1 78.0 51.7 26.0 51.3 40.0 20.1 37.9 27.5 29.8 8.4 5.6 30.9 40.7 27.4 55.3 29.5 31.4 30.8 42.7 7.5 32.2 24.5 28.8 8.5 10.2 39.0 37.6 17.0 18.0 71.2 38.1 46.5 27.8 13.0 0.0 49.1 47.6 35.3 16.9 32.8 68.6 92.5 46.6 18.7 38.4 82.6 RCAN1 DSCR1 ENSG00000159200 "Regulator of calcineurin 1" P53805 21 34513142-34615113 "Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 256.2;parathyroid gland: 453.5" "Cell type enhanced" "Detected in many" "Breast glandular cells: 245.5;Endometrial ciliated cells: 336.9;Glandular and luminal cells: 504.9" "Cancer enhanced" "Detected in all" "glioma: 41.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 5 "SK-MEL-30: 1323.8;WM-115: 815.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037218, HPA068436" Enhanced Approved Cytosol NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 44: Endometrium - Transcription" Cytosol "CAB037218: AB_2179743, HPA068436: " "unprognostic (3.83e-2)" "unprognostic (4.40e-1)" "unprognostic (1.04e-1)" "unprognostic (7.55e-2)" "unprognostic (9.51e-2)" "unprognostic (1.09e-1)" "unprognostic (2.82e-3)" "unprognostic (5.27e-2)" "unprognostic (7.99e-2)" "unprognostic (4.83e-2)" "unprognostic (2.71e-1)" "unprognostic (2.04e-1)" "unprognostic (4.07e-3)" "unprognostic (1.54e-3)" "unprognostic (1.68e-1)" "unprognostic (2.45e-2)" "unprognostic (2.60e-3)" 58.5 22.0 59.0 50.3 68.2 6.3 65.0 64.6 79.8 86.4 69.9 39.0 31.6 28.7 8.9 24.5 12.4 57.4 61.6 57.5 65.7 89.8 256.2 38.6 12.9 68.1 65.3 8.7 64.1 453.5 30.7 95.6 68.3 24.1 39.5 13.1 20.4 15.1 34.4 29.1 27.6 48.7 67.4 14.6 34.9 10.5 72.7 82.2 61.0 31.8 9.7 101.3 20.9 75.0 47.7 9.5 47.9 29.6 25.7 15.9 29.1 175.8 181.3 71.1 70.5 54.1 44.7 0.8 8.1 103.4 139.5 4.1 34.4 35.6 94.5 26.8 21.2 9.5 16.5 25.8 98.1 15.3 28.9 41.4 31.9 84.4 58.7 17.9 23.8 32.5 18.1 45.7 47.7 23.1 145.4 12.2 27.4 48.0 23.5 53.9 37.5 22.2 22.8 81.1 23.0 10.1 128.4 82.2 1323.8 43.3 111.4 25.4 25.8 237.5 24.7 39.9 43.1 38.9 26.4 8.5 77.4 44.4 815.5 0.0 1.1 5.0 0.7 2.1 1.0 1.1 0.8 0.7 1.6 0.8 0.3 0.7 0.5 0.1 2.4 3.0 1.1 0.5 59.0 68.2 64.6 79.8 57.5 65.7 68.1 65.3 68.3 67.4 72.7 75.0 158.3 96.1 52.4 15.3 8.2 94.6 20.7 20.5 38.1 19.4 245.5 142.4 24.9 21.5 32.7 206.0 27.1 10.9 11.8 204.9 21.5 82.0 48.3 336.9 46.4 175.4 3.6 7.4 28.3 18.9 15.3 60.3 23.4 504.9 8.8 3.9 25.0 187.8 58.9 3.3 54.2 30.7 4.1 19.6 74.0 13.1 7.2 39.8 56.9 15.9 29.5 10.9 3.1 41.7 71.3 26.3 140.5 9.8 6.1 16.3 41.2 142.3 14.1 7.5 0.0 30.3 68.9 10.8 2.6 12.3 79.3 11.1 11.5 10.5 16.3 50.4 RCAN2 "DSCR1L1, ZAKI-4" ENSG00000172348 "Regulator of calcineurin 2" Q14206 6 46220736-46491972 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 199.5;tongue: 180.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 255.4;Excitatory neurons: 261.4;Inhibitory neurons: 254.4;Muller glia cells: 183.1;Oligodendrocytes: 294.6;Smooth muscle cells: 138.4" "Cancer enhanced" "Detected in all" "renal cancer: 25.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 17 "gdT-cell: 1.8;memory CD4 T-cell: 1.1;memory CD8 T-cell: 2.2;naive CD8 T-cell: 1.5" "Lineage enriched" "Detected in single" 23 "T-cells: 2.2" "Group enriched" "Detected in some" 6 "fHDF/TERT166: 63.3;HDLM-2: 129.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053880 Uncertain Approved Nucleoplasm,Mitochondria NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" Mitochondria Nucleoplasm "HPA053880: AB_2682290" "unprognostic (2.82e-1)" "unprognostic (7.76e-2)" "unprognostic (4.13e-2)" "unprognostic (1.14e-1)" "unprognostic (5.55e-3)" "unprognostic (4.52e-2)" "unprognostic (1.29e-3)" "unprognostic (1.86e-3)" "unprognostic (2.26e-1)" "unprognostic (4.33e-1)" "prognostic favorable (2.48e-4)" "unprognostic (1.37e-1)" "prognostic favorable (1.12e-6)" "unprognostic (3.83e-2)" "unprognostic (1.98e-1)" "unprognostic (1.02e-1)" "unprognostic (2.11e-2)" 38.1 12.6 35.7 7.7 41.2 0.0 17.1 31.7 106.3 20.3 0.0 20.1 9.8 17.5 51.5 25.9 17.0 35.1 199.5 34.0 65.0 32.4 4.9 16.3 4.1 69.6 76.0 24.0 11.1 85.5 17.5 0.6 68.8 25.3 22.6 61.6 9.6 27.0 73.3 17.2 19.1 14.0 20.6 7.1 36.5 5.7 65.5 4.7 20.1 180.1 7.0 44.0 21.4 62.3 0.0 0.0 1.6 0.0 0.7 0.2 0.1 1.1 15.1 1.1 0.1 0.0 0.0 0.0 0.8 63.3 0.0 0.1 0.0 0.0 0.3 129.7 0.8 0.0 0.0 0.0 1.0 0.0 0.0 1.2 0.0 0.1 0.1 0.0 0.3 0.3 0.0 0.1 5.1 0.0 0.0 0.2 2.7 0.4 0.4 0.4 13.6 0.1 0.2 0.3 4.9 0.0 0.0 0.0 0.0 3.0 0.0 0.1 0.0 0.1 1.8 0.1 0.2 6.8 0.1 0.0 0.2 0.0 0.4 0.0 0.0 0.0 1.8 0.0 0.0 0.0 1.1 2.2 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.4 35.7 41.2 31.7 106.3 34.0 65.0 69.6 76.0 68.8 20.6 65.5 62.3 7.6 6.4 5.8 13.7 0.6 6.2 4.6 0.0 0.0 24.8 1.8 1.4 255.4 8.6 0.0 3.7 4.2 0.1 0.8 1.0 70.5 5.5 40.2 0.8 0.4 17.1 25.1 0.0 261.4 2.5 0.0 22.2 1.5 0.8 0.0 0.3 0.4 1.2 0.1 30.3 254.4 1.5 34.6 0.3 8.0 14.2 29.2 0.9 32.0 46.9 0.0 183.1 0.0 76.9 294.6 2.9 0.3 50.4 0.4 3.3 0.0 1.9 0.0 9.7 98.6 16.4 138.4 1.5 1.4 0.5 7.4 0.0 4.0 0.8 0.3 1.4 RCOR3 FLJ10876 ENSG00000117625 "REST corepressor 3" Q9P2K3 1 211258377-211316385 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 131.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007413, HPA007621, HPA071997" Enhanced Enhanced Nucleoplasm,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm Cytosol "HPA007413: AB_1079796, HPA007621: , HPA071997: AB_2732193" "unprognostic (2.39e-2)" "unprognostic (1.23e-1)" "unprognostic (9.35e-2)" "unprognostic (3.07e-2)" "prognostic favorable (1.35e-5)" "unprognostic (4.02e-3)" "unprognostic (2.28e-2)" "prognostic favorable (5.75e-5)" "unprognostic (2.04e-1)" "unprognostic (1.27e-1)" "unprognostic (5.12e-2)" "unprognostic (9.86e-2)" "unprognostic (1.03e-2)" "unprognostic (3.62e-2)" "unprognostic (1.82e-1)" "unprognostic (3.95e-1)" "unprognostic (3.56e-3)" 16.9 15.6 11.3 10.7 16.1 31.7 19.7 21.8 16.6 20.3 9.2 19.6 12.1 19.1 21.4 14.5 18.2 12.4 22.7 11.1 14.3 15.7 15.9 14.5 15.2 13.4 12.0 26.7 19.7 20.8 16.9 14.9 14.6 23.9 13.8 30.5 19.5 24.5 65.2 19.2 18.7 14.0 11.5 18.6 16.2 33.7 12.6 19.2 31.9 51.7 14.6 18.8 18.0 22.3 15.5 13.9 25.1 14.4 21.3 20.2 26.4 18.3 18.3 20.0 20.2 12.0 20.9 22.8 11.6 23.7 13.9 23.4 20.6 18.2 15.4 21.5 10.9 21.4 22.6 17.0 23.4 34.2 19.8 22.0 16.6 21.9 27.3 22.4 11.8 23.2 21.0 29.2 29.9 11.2 16.8 18.8 27.2 11.3 14.4 17.8 49.6 27.3 17.2 28.5 16.0 32.5 46.7 24.3 33.6 24.1 29.9 23.3 17.1 17.5 19.7 23.2 20.4 23.5 18.4 30.1 15.2 19.6 15.9 27.2 12.4 45.9 8.8 12.5 11.8 15.4 9.4 9.7 13.7 11.4 16.0 11.6 20.8 19.8 14.3 14.5 12.7 8.8 11.3 16.1 21.8 16.6 11.1 14.3 13.4 12.0 14.6 11.5 12.6 22.3 23.1 38.5 44.4 67.6 23.0 14.5 10.7 16.4 29.6 43.7 29.0 25.9 73.4 24.3 24.9 14.7 35.5 26.7 30.2 16.6 21.5 10.4 70.4 22.0 37.4 17.7 34.2 29.8 121.9 15.4 14.8 24.0 28.1 26.6 19.6 21.7 21.8 20.8 20.5 23.5 101.1 17.3 16.2 22.3 14.2 122.6 22.4 24.6 23.2 49.6 22.2 24.1 14.4 87.9 131.6 10.4 15.8 27.1 28.1 12.5 24.1 22.8 22.2 47.7 0.0 33.2 24.8 65.4 35.1 33.1 16.9 25.4 22.6 22.7 17.5 9.0 RDH16 "RODH-4, SDR9C8" ENSG00000139547 "Retinol dehydrogenase 16" O75452 12 56951431-56959374 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 152 "liver: 793.0" "Cell type enriched" "Detected in some" 27 "Hepatocytes: 365.1" "Cancer enriched" "Detected in many" 20 "liver cancer: 44.0" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 2.0;hTCEpi: 4.3;OE19: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA038518 Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 62: Liver - Hemostasis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 2: Hepatocytes - Metabolism" "HPA038518: AB_10672713" "unprognostic (5.42e-3)" "unprognostic (4.20e-2)" "unprognostic (2.99e-2)" "unprognostic (1.14e-1)" "unprognostic (1.88e-1)" "unprognostic (2.92e-2)" "prognostic favorable (2.16e-5)" "unprognostic (8.83e-3)" "unprognostic (1.04e-1)" "unprognostic (2.84e-1)" "unprognostic (6.85e-2)" "unprognostic (6.10e-1)" "unprognostic (7.99e-12)" "unprognostic (2.24e-1)" "unprognostic (1.29e-2)" "unprognostic (1.62e-1)" "unprognostic (2.01e-2)" 0.3 0.3 0.9 0.0 0.9 0.0 0.3 0.9 1.1 1.2 0.9 0.3 0.0 0.4 0.1 1.4 0.5 0.0 0.4 0.9 0.8 0.5 793.0 0.4 0.1 0.8 0.8 0.5 0.6 0.0 0.3 0.0 0.9 5.2 0.0 0.4 0.5 2.4 0.2 2.9 0.5 0.0 0.8 2.5 0.3 1.3 0.8 0.2 0.3 0.0 1.3 0.3 1.6 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 4.3 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.0 1.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.9 0.9 1.1 0.9 0.8 0.8 0.8 0.9 0.8 0.8 0.9 0.1 0.0 0.0 2.0 1.9 0.0 1.2 0.3 0.0 2.2 0.2 0.0 2.0 5.7 0.2 0.0 0.0 0.1 0.2 0.0 0.0 0.1 8.5 0.1 0.1 0.6 0.0 13.5 0.2 0.4 0.0 0.3 0.0 0.1 0.0 0.3 3.6 365.1 0.2 1.7 0.2 0.0 0.0 6.3 0.3 5.8 0.0 0.2 0.0 0.0 0.1 0.3 0.0 0.0 1.8 0.2 0.0 0.0 0.3 5.7 0.0 0.1 0.2 1.0 0.0 0.0 0.1 1.4 0.9 0.8 0.3 0.0 0.6 0.1 0.0 0.3 REEP3 "C10orf74, Yip2b" ENSG00000165476 "Receptor accessory protein 3" Q6NUK4 10 63521401-63625128 "Predicted membrane proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 346.0;Urothelial cells: 270.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "unprognostic (4.85e-2)" "unprognostic (7.07e-3)" "unprognostic (2.89e-2)" "unprognostic (6.25e-2)" "unprognostic (3.50e-3)" "prognostic unfavorable (7.83e-4)" "prognostic unfavorable (3.19e-4)" "unprognostic (1.13e-2)" "unprognostic (9.33e-2)" "unprognostic (2.87e-1)" "prognostic unfavorable (1.32e-4)" "unprognostic (1.16e-1)" "unprognostic (1.29e-1)" "unprognostic (1.89e-2)" "unprognostic (6.82e-2)" "unprognostic (2.18e-1)" "unprognostic (4.06e-2)" 26.5 16.0 10.9 10.3 21.8 2.1 15.9 20.0 12.9 23.5 19.4 16.3 28.3 19.9 16.2 17.1 10.6 15.6 10.5 9.8 15.0 14.0 21.0 17.2 8.8 23.9 20.2 7.4 9.1 29.1 7.0 20.7 23.8 21.6 17.1 6.7 19.8 19.1 6.9 15.5 29.0 25.7 17.8 11.3 13.3 9.2 17.9 6.2 21.0 8.1 9.1 23.6 9.9 35.4 53.6 23.7 21.6 20.7 77.9 76.9 24.3 40.0 66.0 29.9 42.2 33.5 81.2 4.9 14.9 58.5 9.9 61.7 8.7 56.1 52.6 16.3 17.8 11.2 9.7 21.5 50.4 12.5 0.2 65.0 43.2 42.0 63.3 74.2 52.6 6.4 5.5 23.4 54.9 16.3 9.0 19.3 7.5 10.2 50.0 16.0 14.5 10.1 43.1 31.0 6.4 21.7 37.1 36.1 34.7 30.5 35.7 28.6 39.9 28.6 8.6 26.0 31.2 20.0 32.6 7.5 25.8 0.1 30.6 0.1 3.3 2.1 1.6 4.6 3.4 2.0 3.5 2.4 2.9 1.5 1.3 1.9 1.5 1.7 3.0 3.1 5.1 1.6 10.9 21.8 20.0 12.9 9.8 15.0 23.9 20.2 23.8 17.8 17.9 35.4 96.6 28.9 30.4 46.0 25.4 64.5 108.2 46.8 31.9 13.6 76.4 57.1 24.5 34.3 65.9 82.8 27.1 66.7 23.1 113.8 29.4 71.5 346.0 28.9 56.1 64.2 43.0 21.0 96.7 72.1 97.4 56.2 37.8 34.4 9.5 10.7 65.3 71.8 44.2 20.2 37.5 47.0 54.9 38.5 45.4 107.5 105.9 47.6 39.2 65.6 47.1 16.9 13.4 75.9 145.3 156.4 88.3 124.8 47.2 190.8 179.2 46.5 52.1 22.5 98.6 32.0 72.0 133.6 8.8 38.6 73.2 117.5 30.4 42.7 29.4 270.2 RELN "PRO1598, RL" ENSG00000189056 Reelin P78509 7 103471381-103989658 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Developmental protein, Hydrolase, Protease, Serine protease" "Disease variant, Epilepsy, Lissencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 64.4" "Group enriched" "Detected in some" 8 "Hepatic stellate cells: 128.5;Inhibitory neurons: 372.4" "Cancer enhanced" "Detected in many" "liver cancer: 5.7" "Region enriched" "Detected in many" 10 "cerebellum: 64.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 16.2;PC-3: 8.6;SCLC-21H: 11.1;SH-SY5Y: 13.7;TIME: 33.0" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 110.0" HPA077891 Approved "Golgi apparatus,Vesicles" "Secreted in brain" NA NA 30000000 "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" Vesicles "HPA077891: " "unprognostic (1.42e-1)" "unprognostic (2.93e-3)" "unprognostic (4.31e-2)" "unprognostic (1.29e-4)" "unprognostic (1.30e-1)" "unprognostic (6.95e-2)" "unprognostic (1.85e-1)" "unprognostic (8.35e-2)" "unprognostic (1.54e-1)" "unprognostic (1.48e-2)" "unprognostic (3.31e-3)" "unprognostic (3.86e-1)" "unprognostic (2.02e-2)" "unprognostic (1.43e-2)" "unprognostic (3.03e-1)" "unprognostic (1.35e-1)" "unprognostic (3.06e-2)" 1.3 1.8 2.0 0.6 1.8 0.0 2.7 64.4 3.8 1.5 0.6 0.8 0.2 0.4 0.1 0.8 2.8 0.7 1.7 3.3 6.4 0.4 13.4 0.5 0.4 2.6 4.2 0.4 0.1 0.0 0.5 0.0 6.3 0.6 0.9 2.9 0.8 0.9 0.2 0.6 0.9 0.7 3.9 0.3 0.5 0.7 0.5 0.0 1.7 1.1 0.2 0.7 0.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 2.1 0.0 0.1 0.0 0.0 4.3 0.0 16.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.6 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.0 1.9 0.0 0.0 0.0 11.1 13.7 0.0 0.0 0.0 0.0 0.0 0.0 33.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 1.8 64.4 3.8 3.3 6.4 2.6 4.2 6.3 3.9 0.5 0.5 1.0 0.0 0.0 9.1 0.5 0.6 0.0 0.0 0.6 30.2 0.5 0.4 5.1 4.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 13.6 0.1 0.0 8.3 0.0 7.0 2.6 1.2 0.1 7.5 0.0 0.1 0.0 0.0 128.5 3.3 0.2 0.0 372.4 0.0 0.0 5.3 2.2 6.1 0.0 0.1 0.0 2.8 0.0 0.2 0.0 3.0 10.3 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.3 0.0 0.8 0.7 0.1 0.8 0.0 0.6 0.3 0.4 0.0 0.0 0.0 REM2 FLJ38964 ENSG00000139890 "RRAD and GEM like GTPase 2" Q8IYK8 14 22883222-22887678 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 9.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 12.8;Early spermatids: 29.2;Endometrial ciliated cells: 10.9;Late spermatids: 9.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "neutrophil: 3.7" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "AF22: 3.1" "Region enhanced" "Detected in all" "basal ganglia: 44.8" "Group enriched" "Detected in some" 5 "basal ganglia: 8.3;cerebellum: 4.6;hippocampal formation: 3.2;midbrain: 2.2" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 12: NES - Nervous system development" "Cluster 29: Early spermatids - Spermatogenesis" "unprognostic (4.56e-3)" "unprognostic (1.89e-2)" "unprognostic (1.47e-1)" "unprognostic (3.95e-1)" "unprognostic (1.49e-1)" "unprognostic (9.50e-2)" "unprognostic (1.11e-1)" "unprognostic (1.21e-2)" "unprognostic (1.54e-1)" "unprognostic (1.66e-3)" "unprognostic (1.49e-5)" "unprognostic (9.40e-2)" "unprognostic (4.63e-5)" "unprognostic (3.56e-1)" "unprognostic (2.72e-1)" "unprognostic (9.93e-2)" "unprognostic (2.49e-2)" 0.7 0.4 1.0 0.9 3.3 9.9 0.7 1.4 2.1 1.2 2.0 1.3 0.3 0.8 0.4 0.7 2.6 0.3 0.4 1.3 1.6 1.6 0.6 2.3 0.9 1.1 1.2 1.1 0.6 1.3 5.8 0.2 0.8 1.5 0.1 0.5 0.8 0.3 0.8 2.2 2.0 0.3 0.8 5.8 0.9 4.8 2.2 0.6 1.0 0.3 0.5 1.0 0.9 0.8 0.7 0.3 3.1 0.1 0.3 0.4 0.4 0.0 0.2 0.0 0.2 0.3 1.0 0.3 0.1 0.0 0.1 1.3 0.0 0.1 0.2 0.5 0.7 0.1 1.5 0.0 0.2 0.1 0.2 0.1 0.0 0.0 0.0 0.1 0.1 0.2 0.1 1.3 0.2 1.0 0.0 0.3 0.1 0.3 0.6 0.0 0.1 0.3 0.1 0.1 0.4 1.5 0.3 0.4 0.5 0.1 0.5 0.2 0.0 0.0 0.7 0.0 0.1 1.2 0.5 0.8 0.1 0.0 0.0 0.3 0.0 0.4 0.1 0.0 0.3 0.6 0.2 0.3 0.0 0.9 0.4 0.5 3.7 0.0 0.4 0.2 0.2 0.1 1.0 3.3 1.4 2.1 1.3 1.6 1.1 1.2 0.8 0.8 2.2 0.8 1.6 12.8 2.4 0.0 4.0 2.8 0.9 1.2 4.0 0.1 4.7 4.3 1.7 1.5 1.9 1.8 0.0 0.5 3.5 1.4 0.0 0.7 29.2 10.9 1.3 1.1 6.6 0.4 0.2 0.0 0.3 0.7 1.5 4.7 0.0 0.6 0.4 0.0 0.4 0.0 0.1 1.9 0.0 0.6 1.0 9.6 1.2 0.6 3.6 0.0 1.3 0.7 0.0 0.0 0.1 0.4 0.2 1.2 3.1 0.9 0.4 0.5 4.6 0.9 0.0 0.4 0.9 0.8 0.8 4.5 3.0 0.4 1.7 0.3 1.2 1.3 REN ENSG00000143839 Renin P00797 1 204154819-204190324 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Aspartyl protease, Hydrolase, Protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "kidney: 162.2" "Cell type enhanced" "Detected in some" "Early spermatids: 6.8;Late spermatids: 28.4;Paneth cells: 5.6;Smooth muscle cells: 10.7;Urothelial cells: 7.0" "Cancer enriched" "Detected in many" 8 "renal cancer: 39.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 1.0;BJ: 2.0;HMC-1: 2.6;SK-BR-3: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA005131 Approved "Secreted to blood" NA NA 692000 10000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 33: Fibroblasts - ECM organization" "HPA005131: AB_1079174" "unprognostic (4.45e-2)" "unprognostic (3.35e-1)" "unprognostic (1.62e-1)" "unprognostic (8.58e-2)" "unprognostic (2.89e-1)" "unprognostic (1.23e-2)" "unprognostic (1.24e-1)" "unprognostic (1.13e-1)" "unprognostic (7.20e-3)" "unprognostic (1.37e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (6.45e-5)" "unprognostic (1.22e-1)" "unprognostic (1.70e-1)" "unprognostic (4.98e-2)" "unprognostic (6.49e-2)" 1.0 1.4 0.3 0.2 0.9 0.0 0.1 0.0 0.2 4.3 3.2 0.4 0.3 9.6 0.3 0.2 2.3 0.1 1.8 0.2 0.0 162.2 0.7 0.7 0.0 0.3 0.4 16.3 0.0 0.0 0.6 15.2 0.1 0.3 0.2 0.1 0.8 0.8 0.0 0.1 0.1 1.5 0.0 0.1 0.0 0.9 0.2 0.5 0.0 0.0 0.5 5.2 0.3 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 2.0 0.4 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 1.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.9 0.0 0.2 0.2 0.0 0.3 0.4 0.1 0.0 0.2 0.0 0.0 0.0 1.5 1.0 0.0 0.0 0.8 0.7 0.0 0.7 0.1 0.0 0.2 0.0 0.3 1.8 0.0 0.3 0.0 0.0 0.0 1.2 6.8 0.2 0.5 0.4 0.0 0.0 0.3 1.1 0.2 2.8 0.0 0.5 0.0 0.0 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.0 28.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.0 5.6 0.4 0.0 1.8 0.0 0.0 0.0 0.3 0.0 0.0 10.7 0.3 0.2 0.0 0.0 1.1 0.1 1.3 0.0 7.0 RET "CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51" ENSG00000165731 "Ret proto-oncogene" P07949 10 43077064-43130351 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Hirschsprung disease, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "adrenal gland: 20.8;brain: 27.3;parathyroid gland: 31.8" "Group enriched" "Detected in some" 4 "Horizontal cells: 79.1;Ionocytes: 26.4;Skeletal myocytes: 23.1" "Cancer enhanced" "Detected in many" "breast cancer: 11.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MCF7: 74.6;NB-4: 42.2;SH-SY5Y: 329.3;THP-1: 95.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "midbrain: 53.3;spinal cord: 19.4" "CAB002581, HPA008356, HPA008495" Approved Supported Approved "Golgi apparatus,Plasma membrane,Cytosol" No NA 2100000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Cytosol" "Plasma membrane" "CAB002581: AB_563673, HPA008356: AB_1847232, HPA008495: " "unprognostic (7.94e-2)" "unprognostic (3.68e-2)" "unprognostic (4.49e-1)" "prognostic unfavorable (5.02e-4)" "unprognostic (1.15e-1)" "unprognostic (9.13e-4)" "unprognostic (1.27e-2)" "unprognostic (3.62e-2)" "unprognostic (2.86e-1)" "unprognostic (2.01e-1)" "unprognostic (1.54e-3)" "unprognostic (4.43e-1)" "unprognostic (9.35e-5)" "unprognostic (1.64e-3)" "unprognostic (8.28e-2)" "unprognostic (3.67e-3)" "unprognostic (2.02e-2)" 1.8 20.8 1.0 1.3 0.9 0.4 1.1 5.1 5.6 1.0 0.2 3.4 1.4 0.6 0.3 0.4 0.5 0.6 2.2 0.3 5.5 0.9 3.0 0.4 0.6 14.4 27.3 0.4 1.3 31.8 5.3 0.5 12.0 1.8 1.4 4.7 5.1 2.0 5.9 0.9 1.4 1.0 4.8 0.2 2.2 2.7 7.6 1.6 0.8 3.1 0.2 0.6 1.4 5.8 0.1 0.4 0.1 1.7 0.0 0.0 0.1 0.7 0.2 0.4 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.0 5.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 7.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 74.6 0.0 42.2 7.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 4.7 329.3 0.1 0.0 0.1 0.5 4.1 95.9 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.7 0.1 0.0 1.0 0.9 5.1 5.6 0.3 5.5 14.4 27.3 12.0 4.8 7.6 5.8 0.4 0.0 0.5 1.6 0.0 0.3 0.8 0.0 0.0 1.7 6.0 0.5 2.1 0.0 0.0 0.0 0.0 0.0 2.1 0.2 0.0 0.0 1.5 0.0 0.3 1.1 0.0 0.0 4.2 0.2 2.3 6.8 0.0 0.0 1.3 0.5 0.0 1.2 0.1 79.1 8.6 1.9 26.4 0.0 0.6 1.5 0.3 0.5 0.0 1.0 0.0 0.8 0.0 1.0 0.6 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.8 1.7 0.0 23.1 1.2 1.1 4.7 0.0 0.6 0.0 0.2 0.3 0.2 0.1 REXO5 NEF-sp ENSG00000005189 "RNA exonuclease 5" Q96IC2 16 20806429-20849665 "Predicted intracellular proteins" "Exonuclease, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "testis: 343.8" "Cell type enriched" "Detected in some" 5 "Granulosa cells: 26.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 15 "basophil: 86.7" "Lineage enriched" "Detected in many" 39 "granulocytes: 86.7" "Cell line enhanced" "Detected in many" "K-562: 44.7;U-266/70: 42.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA040755, HPA040868, HPA066145" Approved Approved "Nuclear membrane,Nucleoli,Endoplasmic reticulum" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 16: U-266 - Nucleosome" "Cluster 40: Granulosa cells - Unknown function" "Nuclear membrane" "Nucleoli, Endoplasmic reticulum" "HPA040755: AB_10965790, HPA040868: AB_10963549, HPA066145: " "unprognostic (2.39e-1)" "unprognostic (2.09e-3)" "unprognostic (1.09e-2)" "unprognostic (1.15e-1)" "unprognostic (1.68e-1)" "unprognostic (5.63e-2)" "unprognostic (9.15e-2)" "unprognostic (6.24e-2)" "unprognostic (2.26e-1)" "unprognostic (1.80e-2)" "unprognostic (8.24e-2)" "unprognostic (4.72e-2)" "unprognostic (2.42e-4)" "unprognostic (1.01e-2)" "unprognostic (8.23e-2)" "unprognostic (2.00e-1)" "unprognostic (6.93e-2)" 2.3 1.8 1.4 1.8 1.4 11.6 3.6 1.6 2.0 1.7 0.4 2.1 2.9 2.2 1.2 2.3 4.2 1.6 3.4 1.4 2.3 1.2 1.8 1.0 2.9 1.7 1.1 1.9 1.7 40.0 0.9 1.5 1.6 5.3 3.0 4.2 1.7 1.3 1.0 2.2 2.1 2.7 0.8 1.0 5.0 343.8 2.2 7.4 0.9 1.3 2.6 2.0 1.6 2.1 11.3 6.5 10.1 4.5 4.2 7.5 3.4 7.6 8.4 8.2 8.9 4.7 10.0 7.0 11.5 6.7 5.7 5.7 7.7 3.4 8.5 6.5 4.9 11.7 10.2 6.7 0.8 17.2 16.4 3.8 1.5 9.7 12.4 3.5 2.8 0.0 44.7 29.8 20.5 15.1 2.8 13.5 5.5 4.6 6.6 14.0 18.8 12.6 2.5 4.0 8.6 9.7 7.3 9.6 2.4 2.9 16.2 14.8 1.4 6.1 5.4 8.2 9.3 42.5 31.1 2.7 12.6 22.3 5.6 86.7 0.4 5.7 0.3 0.1 0.4 0.0 0.4 0.4 0.7 0.0 0.1 0.3 0.4 2.2 0.2 0.2 1.8 0.4 1.4 1.4 1.6 2.0 1.4 2.3 1.7 1.1 1.6 0.8 2.2 2.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 3.4 0.0 0.0 1.3 0.0 0.0 3.2 0.8 0.0 0.0 1.6 0.0 2.8 1.6 0.6 0.0 0.0 0.0 1.5 2.4 1.5 0.0 1.7 1.3 26.4 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 1.6 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.1 0.0 0.0 0.6 1.5 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.5 0.5 4.7 0.0 0.0 RFESD ENSG00000175449 "Rieske Fe-S domain containing" Q8TAC1 5 95646754-95684773 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 26.9" "Cell type enriched" "Detected in many" 7 "Erythroid cells: 278.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 41.3;K-562: 78.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB016546 Uncertain Approved Nucleoplasm NA NA 48000 "Cluster 32: T-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 1: K-562 - Erythropoiesis" "Cluster 6: Erythroid cells - Oxygen transport" Nucleoplasm "CAB016546: AB_630417" "unprognostic (1.15e-1)" "unprognostic (5.40e-2)" "unprognostic (1.06e-1)" "unprognostic (1.37e-2)" "unprognostic (6.07e-3)" "unprognostic (2.72e-1)" "unprognostic (1.33e-3)" "unprognostic (1.04e-1)" "unprognostic (1.14e-1)" "unprognostic (9.91e-2)" "unprognostic (8.24e-3)" "unprognostic (4.89e-2)" "unprognostic (5.83e-3)" "unprognostic (6.78e-2)" "unprognostic (9.03e-2)" "unprognostic (9.35e-2)" "unprognostic (1.09e-1)" 1.7 2.3 1.3 1.1 1.7 26.9 2.8 2.1 3.4 2.2 1.8 1.8 1.2 2.0 4.4 2.4 2.0 1.2 3.5 1.4 1.6 2.5 2.5 1.5 3.1 1.8 1.6 2.9 3.6 3.9 2.8 1.6 1.7 3.1 1.4 3.6 4.7 1.4 5.8 7.6 1.4 1.4 1.6 2.4 2.5 12.2 1.7 4.9 3.3 3.5 3.2 2.3 1.9 2.2 3.6 5.5 1.0 3.5 3.4 6.2 0.0 1.9 2.9 3.1 3.1 4.4 3.8 5.8 3.8 1.6 7.3 5.2 3.8 3.0 3.3 8.7 3.3 41.3 5.2 1.6 4.3 3.8 4.2 2.8 5.5 4.0 3.6 2.8 3.1 17.1 78.3 4.5 4.9 2.4 12.4 16.4 4.4 1.6 5.2 6.0 0.7 2.6 1.1 2.1 5.3 3.8 5.4 2.4 0.0 0.3 2.8 2.0 1.6 3.9 3.1 2.9 3.4 3.9 10.1 4.7 3.4 4.5 2.1 0.0 0.7 0.4 3.6 0.9 9.6 3.9 8.7 6.2 1.6 3.3 12.7 7.5 0.0 6.1 0.9 1.9 5.4 2.7 1.3 1.7 2.1 3.4 1.4 1.6 1.8 1.6 1.7 1.6 1.7 2.2 2.0 12.8 3.3 1.6 2.8 3.2 4.5 6.0 3.4 2.1 2.3 3.4 7.8 0.0 5.5 1.8 0.0 3.5 4.2 0.5 1.9 2.4 18.2 2.3 2.4 1.4 0.0 278.7 1.6 1.8 12.1 3.2 2.0 1.8 3.8 2.0 2.9 2.1 3.8 1.7 1.9 1.1 14.2 1.6 0.8 8.5 1.8 1.2 0.0 2.8 2.3 3.8 3.1 0.0 1.7 1.7 0.3 1.2 1.0 2.5 0.9 2.9 5.3 1.9 6.6 2.8 2.7 37.2 14.3 4.5 6.8 2.1 4.6 2.5 1.2 2.5 RFT1 CDG1N ENSG00000163933 "RFT1 homolog" Q96AA3 3 53088483-53130453 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 39.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060327, HPA069022" Approved Approved Vesicles NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 29: Non-specific - Vesicular transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "HPA060327: AB_2684253, HPA069022: AB_2732126" "unprognostic (5.74e-2)" "unprognostic (1.31e-1)" "unprognostic (1.35e-3)" "unprognostic (5.16e-3)" "unprognostic (2.08e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.69e-4)" "unprognostic (1.09e-1)" "unprognostic (1.22e-1)" "unprognostic (2.70e-1)" "unprognostic (2.81e-2)" "unprognostic (9.26e-2)" "unprognostic (6.48e-2)" "unprognostic (1.96e-1)" "unprognostic (1.22e-1)" "unprognostic (5.06e-2)" "unprognostic (3.54e-2)" 11.8 12.5 5.7 14.5 6.2 8.3 12.5 5.5 6.6 9.0 4.9 11.8 10.3 9.1 13.0 12.1 12.4 10.5 9.0 6.1 5.3 8.7 14.0 9.2 16.7 5.6 5.2 12.5 22.3 15.6 6.2 13.8 5.9 9.3 13.2 4.3 18.0 10.4 5.1 9.9 10.5 11.2 5.5 9.9 10.4 13.5 5.4 14.2 14.6 6.7 15.8 12.6 8.8 8.0 39.1 36.3 24.3 39.0 27.9 29.5 50.6 34.8 32.3 59.2 53.7 35.9 74.6 51.0 21.3 33.5 55.6 40.7 55.4 56.8 51.9 48.4 24.5 50.6 24.8 36.0 48.8 46.7 28.4 31.4 46.8 79.6 57.1 26.2 37.9 52.7 27.1 45.2 39.4 39.6 44.2 27.3 48.8 67.5 47.3 18.1 23.5 77.5 32.8 26.1 13.8 18.7 43.0 30.9 31.2 26.2 23.3 65.5 25.5 54.3 35.2 37.7 69.1 28.6 37.1 38.4 38.9 58.8 58.3 50.2 40.2 18.4 22.2 40.5 22.5 21.2 20.6 22.9 42.9 35.5 23.7 23.7 13.4 23.1 29.4 48.9 20.1 25.7 5.7 6.2 5.5 6.6 6.1 5.3 5.6 5.2 5.9 5.5 5.4 8.0 6.0 3.2 3.7 8.8 8.7 5.0 10.8 18.3 5.2 4.6 7.6 5.5 7.4 11.5 12.6 9.2 4.2 39.4 6.0 5.1 1.9 17.4 1.9 5.6 9.5 8.1 2.4 17.7 9.4 21.1 33.1 9.2 4.1 5.7 2.5 17.8 10.4 10.7 22.0 5.0 8.9 6.4 10.2 9.9 5.0 2.3 8.7 9.8 7.2 9.4 11.7 5.8 3.1 7.5 11.3 12.2 8.8 6.0 19.3 9.1 5.7 5.6 8.3 6.4 0.0 7.0 8.7 10.1 8.9 8.0 4.3 24.2 7.7 22.0 11.7 8.1 RFX4 ENSG00000111783 "Regulatory factor X4" Q33E94 12 106583004-106762803 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 54.1;testis: 75.0" "Group enriched" "Detected in some" 5 "Astrocytes: 346.7;Spermatocytes: 98.7" "Cancer enriched" "Detected in single" 54 "glioma: 15.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 14 "AF22: 48.0" "Low region specificity" "Detected in all" HPA050527 Enhanced Approved Nucleoplasm NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 12: NES - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "HPA050527: AB_2681158" "unprognostic (3.67e-1)" "unprognostic (4.86e-2)" "unprognostic (1.76e-3)" "unprognostic (1.60e-2)" "unprognostic (1.09e-1)" "unprognostic (6.97e-2)" "unprognostic (7.97e-2)" "unprognostic (3.04e-1)" "unprognostic (6.80e-2)" "unprognostic (2.72e-3)" "unprognostic (1.66e-3)" "unprognostic (1.15e-2)" "unprognostic (1.30e-2)" "unprognostic (5.46e-2)" 0.1 0.0 32.0 0.0 36.0 0.0 0.0 32.8 27.6 0.0 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 28.8 54.1 0.0 0.0 0.0 0.0 52.7 46.7 0.0 0.1 0.0 9.9 0.0 40.2 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 40.5 0.0 0.0 75.0 38.8 0.0 0.1 0.0 0.0 0.0 0.0 34.0 0.0 0.3 48.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 3.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 32.0 36.0 32.8 27.6 28.8 54.1 52.7 46.7 40.2 40.5 38.8 34.0 0.0 0.0 0.0 346.7 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 41.8 0.0 0.1 0.2 0.0 0.0 13.7 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 13.4 0.0 0.0 0.0 0.0 29.2 2.1 0.0 0.0 7.5 0.1 0.1 0.0 27.6 2.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.9 0.1 98.7 2.9 0.0 0.0 0.0 0.2 0.1 0.0 0.0 RGCC "bA157L14.2, C13orf15, RGC-32, RGC32" ENSG00000102760 "Regulator of cell cycle" Q9H4X1 13 41457550-41470871 "Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 415.4;lung: 694.9" "Cell type enhanced" "Detected in many" "Adipocytes: 1286.2;Basal prostatic cells: 676.2;Langerhans cells: 590.1;Prostatic glandular cells: 1415.5;T-cells: 532.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 159.9;T-reg: 90.9" "Lineage enriched" "Detected in many" 15 "T-cells: 159.9" "Cell line enhanced" "Detected in many" "ASC TERT1: 57.5;BJ hTERT+: 316.0;Daudi: 105.1;U-698: 111.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035638, HPA063701" Enhanced Supported Nucleoplasm,Nucleoli "Intracellular and membrane" No No 910000 "Cluster 20: T-cells - T-cell receptor" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Nucleoli "HPA035638: AB_10670152, HPA063701: AB_2685096" "unprognostic (1.39e-3)" "unprognostic (4.61e-2)" "prognostic unfavorable (5.60e-4)" "unprognostic (2.28e-1)" "unprognostic (4.27e-2)" "unprognostic (2.85e-1)" "unprognostic (1.49e-3)" "unprognostic (1.49e-2)" "unprognostic (3.99e-2)" "unprognostic (1.57e-3)" "unprognostic (1.19e-1)" "unprognostic (1.17e-1)" "unprognostic (2.81e-2)" "unprognostic (3.04e-3)" "unprognostic (1.48e-1)" "unprognostic (2.30e-1)" "unprognostic (1.42e-3)" 197.6 21.5 186.3 27.7 226.9 415.4 132.6 218.8 236.7 36.1 148.2 34.7 16.9 43.6 7.6 18.6 31.1 42.2 145.9 195.8 196.6 56.9 25.0 694.9 38.1 209.1 204.8 9.1 41.3 48.1 35.3 150.7 205.3 61.5 9.2 5.7 111.5 19.0 47.3 58.0 29.1 33.5 186.7 37.0 37.8 24.8 198.2 70.5 144.0 61.8 21.0 47.5 39.6 241.0 1.1 0.5 34.9 0.0 6.7 57.5 1.4 0.8 316.0 0.2 1.2 44.8 0.7 105.1 0.9 4.0 0.1 1.0 1.2 2.1 0.4 11.1 5.1 0.0 7.9 3.5 3.3 3.7 1.2 4.5 6.7 1.2 43.1 0.6 36.1 24.0 8.3 0.1 1.0 0.3 24.0 2.3 0.5 4.7 0.8 0.1 0.0 0.1 0.3 0.0 1.3 0.4 0.3 0.0 0.7 3.0 0.9 20.1 24.6 0.2 3.8 2.2 0.4 0.2 0.1 111.9 0.3 2.4 0.8 0.0 0.8 0.1 5.6 0.5 5.6 5.3 46.5 14.7 6.1 10.7 159.9 35.0 0.6 0.4 0.1 1.8 90.9 10.2 186.3 226.9 218.8 236.7 195.8 196.6 209.1 204.8 205.3 186.7 198.2 241.0 1286.2 246.8 39.8 57.5 131.8 86.5 676.2 15.2 14.2 1.0 269.9 314.7 25.8 1.5 37.5 3.7 2.1 6.4 249.2 3.0 35.2 0.6 42.3 103.0 47.2 474.6 84.8 322.7 2.5 0.0 9.3 205.1 65.2 69.0 48.9 0.3 31.8 2.5 349.1 0.0 1.2 22.1 14.2 32.0 590.1 13.2 8.1 315.9 193.9 36.5 6.4 1.5 4.1 51.8 115.3 0.3 4.5 2.2 371.2 1415.5 0.1 0.8 33.7 3.1 124.9 45.4 116.0 155.3 5.0 11.2 65.1 11.1 532.4 43.8 7.8 159.7 RGMA RGM ENSG00000182175 "Repulsive guidance molecule BMP co-receptor a" Q96B86 15 93035273-93089204 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 126.3;skeletal muscle: 199.1" "Cell type enhanced" "Detected in many" "Astrocytes: 143.3;Leydig cells: 119.0;Peritubular cells: 116.9;Prostatic glandular cells: 61.3;Skeletal myocytes: 69.3;Squamous epithelial cells: 58.3" "Cancer enriched" "Detected in many" 6 "glioma: 26.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 50.0;BEWO: 14.6;MOLT-4: 15.5;NTERA-2: 22.2;REH: 13.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012343, HPA039880, HPA044222" Approved Approved Nucleoplasm,Cytosol "Secreted - unknown location" NA NA 2000000 "Cluster 80: Striated muscle - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Cytosol "CAB012343: AB_777667, HPA039880: AB_2676723, HPA044222: AB_2678861" "unprognostic (3.21e-2)" "unprognostic (1.59e-1)" "unprognostic (8.85e-2)" "unprognostic (3.96e-3)" "unprognostic (5.73e-2)" "unprognostic (4.72e-3)" "unprognostic (2.53e-2)" "prognostic favorable (2.78e-4)" "unprognostic (2.19e-2)" "unprognostic (1.12e-1)" "unprognostic (2.11e-1)" "unprognostic (6.25e-2)" "unprognostic (3.59e-4)" "unprognostic (8.11e-2)" "unprognostic (2.92e-2)" "unprognostic (1.73e-1)" "unprognostic (7.98e-5)" 30.2 3.2 62.1 22.5 73.8 0.4 30.3 72.5 59.1 55.9 7.7 79.4 9.9 50.9 2.9 57.4 39.9 7.7 29.4 60.4 68.0 3.6 0.6 4.6 2.4 126.3 113.9 38.5 11.4 0.8 6.9 1.3 70.4 12.8 6.2 1.0 24.2 6.4 199.1 17.1 42.9 60.6 91.5 1.3 73.6 33.5 120.6 2.6 10.0 45.0 3.4 10.0 29.2 62.8 2.1 0.3 50.0 0.8 10.3 5.7 14.6 0.3 0.0 0.0 0.0 0.6 0.6 0.1 0.2 0.4 0.0 3.4 8.4 0.2 0.0 0.0 9.2 0.1 0.3 0.0 0.0 0.1 0.2 6.1 0.2 0.0 0.0 0.3 0.0 0.9 0.0 0.1 0.0 1.0 15.5 0.2 22.2 0.1 0.0 13.1 11.4 0.1 0.0 0.5 5.1 3.0 0.5 0.2 0.0 2.6 4.0 2.7 0.0 0.1 10.4 0.3 0.1 0.1 0.0 0.2 0.2 0.2 1.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 62.1 73.8 72.5 59.1 60.4 68.0 126.3 113.9 70.4 91.5 120.6 62.8 4.2 0.0 1.5 143.3 0.5 5.5 20.4 10.2 40.5 1.9 7.5 4.4 4.4 0.0 3.9 0.0 2.1 4.4 0.5 0.3 0.0 6.5 1.2 0.6 10.9 2.7 0.0 0.4 16.8 0.7 1.2 40.5 1.5 2.3 0.0 0.6 1.8 0.3 2.1 0.0 2.8 0.0 12.2 2.5 2.3 6.4 119.0 1.6 3.6 9.4 0.6 4.5 0.0 11.1 1.6 0.4 0.0 116.9 0.1 61.3 0.0 0.1 1.3 1.2 13.1 69.3 20.3 0.9 43.8 58.3 2.8 2.5 1.4 0.1 0.1 29.2 RGP1 KIAA0258 ENSG00000107185 "RGP1 homolog, RAB6A GEF complex partner 1" Q92546 9 35749287-35758585 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020414, HPA021085" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 40: Granulosa cells - Unknown function" Cytosol "Plasma membrane" "HPA020414: AB_1852289, HPA021085: AB_1852291" "unprognostic (2.10e-1)" "unprognostic (3.22e-2)" "unprognostic (1.03e-1)" "unprognostic (2.01e-2)" "unprognostic (3.35e-2)" "unprognostic (1.47e-1)" "prognostic unfavorable (7.09e-4)" "unprognostic (2.22e-1)" "unprognostic (5.42e-2)" "unprognostic (1.51e-3)" "unprognostic (1.81e-3)" "unprognostic (9.77e-2)" "prognostic favorable (8.55e-13)" "unprognostic (2.46e-2)" "unprognostic (1.68e-1)" "unprognostic (3.03e-3)" "unprognostic (1.18e-1)" 9.8 10.4 7.5 8.7 6.9 5.6 8.5 6.6 6.7 7.9 3.4 12.9 10.7 8.8 7.8 8.6 8.3 6.0 12.9 7.3 7.8 11.5 7.4 9.1 7.5 5.8 6.3 10.1 10.7 19.1 10.5 9.3 6.0 8.7 13.4 7.8 11.0 11.4 17.3 9.4 11.6 9.8 5.6 7.4 10.3 6.4 8.0 8.9 12.2 18.6 9.6 8.0 6.5 5.9 18.0 16.6 18.9 15.8 17.3 18.6 11.1 13.9 20.1 18.9 17.4 14.2 6.7 13.9 9.7 17.8 34.9 9.9 18.3 26.2 15.5 18.6 10.7 11.9 32.9 10.7 16.3 13.0 16.1 18.8 32.8 19.9 24.0 27.0 22.7 10.6 8.2 7.5 17.3 8.5 4.0 4.7 7.9 14.7 19.2 13.2 13.5 9.9 16.5 12.4 13.8 14.9 12.3 17.0 11.2 16.6 14.2 6.2 29.0 15.1 18.9 10.5 11.8 11.1 16.5 14.3 21.5 5.4 19.7 1.1 0.2 0.4 0.7 0.4 1.1 0.8 0.5 0.8 0.1 1.0 0.6 0.7 0.7 1.1 0.6 0.6 0.5 0.2 7.5 6.9 6.6 6.7 7.3 7.8 5.8 6.3 6.0 5.6 8.0 5.9 13.9 6.4 12.6 0.0 23.4 5.7 24.5 14.8 9.1 40.8 15.0 10.0 16.6 18.6 15.8 27.6 20.9 10.9 19.1 46.1 13.7 20.1 17.5 9.8 8.3 14.9 43.3 8.6 0.2 17.6 10.6 7.5 18.8 14.9 5.7 33.4 16.1 16.4 7.5 16.8 0.1 26.0 22.4 7.7 6.1 36.8 8.4 5.7 1.8 0.0 11.1 18.8 25.7 0.0 0.1 20.6 38.3 10.9 15.2 25.3 36.3 14.2 17.7 22.3 6.6 11.8 9.3 16.6 6.1 8.1 5.3 10.3 16.4 7.1 28.9 28.8 RGS18 RGS13 ENSG00000150681 "Regulator of G protein signaling 18" Q9NS28 1 192158462-192185815 "Predicted intracellular proteins" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 13.2;lymphoid tissue: 25.4" "Cell type enriched" "Detected in some" 4 "Macrophages: 527.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 353.1" "Lineage enriched" "Detected in many" 4 "granulocytes: 353.1" "Group enriched" "Detected in some" 5 "HEL: 60.2;HL-60: 46.7;NB-4: 43.6;U-937: 39.9" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA028727, HPA045780" Uncertain Approved "Golgi apparatus" NA NA 340000 "Cluster 2: Granulocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" "Golgi apparatus" "HPA028727: AB_2797219, HPA045780: AB_10962728" "unprognostic (3.09e-2)" "unprognostic (4.32e-2)" "unprognostic (8.66e-2)" "unprognostic (1.70e-1)" "unprognostic (2.28e-1)" "unprognostic (1.52e-2)" "unprognostic (1.48e-1)" "unprognostic (2.18e-2)" "unprognostic (2.58e-1)" "unprognostic (1.87e-1)" "unprognostic (3.07e-1)" "unprognostic (2.36e-1)" "unprognostic (1.30e-3)" "unprognostic (8.21e-3)" "unprognostic (2.81e-4)" "unprognostic (1.73e-2)" "unprognostic (9.91e-2)" 4.3 2.3 0.7 14.1 0.6 13.2 2.3 0.9 0.7 2.4 0.9 2.4 2.9 1.0 0.5 1.9 1.3 5.3 0.8 0.6 1.2 1.0 5.3 4.1 8.4 1.5 1.0 0.8 0.8 0.4 0.3 2.2 1.5 1.1 2.9 0.6 0.7 1.0 0.9 0.4 5.8 2.9 1.3 25.4 1.9 0.4 0.8 4.2 0.8 3.1 4.4 4.8 0.4 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 60.2 0.0 0.0 0.0 46.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 2.7 0.0 0.0 0.0 43.6 0.0 0.0 0.0 0.0 0.0 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 39.9 0.0 195.5 50.7 353.1 0.8 66.7 6.8 0.1 0.8 1.3 51.0 0.2 0.1 0.2 164.8 0.6 82.1 12.0 0.0 94.4 0.7 0.6 0.9 0.7 0.6 1.2 1.5 1.0 1.5 1.3 0.8 1.6 0.3 6.4 0.0 0.0 2.9 0.3 0.0 0.0 0.0 0.0 0.2 0.6 0.4 0.0 1.8 0.0 0.0 0.0 22.5 0.0 0.0 0.0 0.1 0.0 0.0 3.3 0.0 16.0 0.0 0.0 0.0 0.8 0.0 0.0 24.7 0.0 5.7 1.1 7.3 0.0 0.0 0.0 0.0 124.9 27.3 0.8 0.3 527.4 0.0 15.9 128.3 0.1 28.8 0.0 0.0 0.0 0.0 0.4 1.1 0.0 0.0 0.3 1.5 0.3 13.1 0.3 0.1 0.1 0.2 0.1 0.1 0.1 7.6 0.0 0.1 0.0 RGS7 ENSG00000182901 "Regulator of G protein signaling 7" P49802 1 240775514-241357230 "Plasma proteins, Predicted intracellular proteins" "GTPase activation, Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 8.0;brain: 28.1;retina: 12.8" "Cell type enhanced" "Detected in some" "Astrocytes: 288.3;Excitatory neurons: 1353.2;Inhibitory neurons: 1095.0;Oligodendrocyte precursor cells: 615.8" "Cancer enhanced" "Detected in some" "glioma: 1.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+ SV40 Large T+: 6.2;HaCaT: 5.3;hTERT-HME1: 7.2;RH-30: 6.4;SH-SY5Y: 5.6;U-2 OS: 5.9;U-251 MG: 7.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB017561 Enhanced Supported Mitochondria,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 6: Brain - Smell perception" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol Mitochondria "CAB017561: AB_2285043" "unprognostic (6.48e-2)" "unprognostic (4.30e-2)" "unprognostic (4.67e-2)" "unprognostic (6.65e-2)" "unprognostic (7.84e-3)" "unprognostic (4.09e-2)" "unprognostic (1.49e-2)" "unprognostic (3.61e-1)" "unprognostic (1.42e-2)" "unprognostic (2.51e-4)" "unprognostic (3.54e-1)" "unprognostic (2.19e-2)" "unprognostic (2.23e-1)" "unprognostic (2.64e-2)" "unprognostic (2.28e-1)" 0.0 8.0 11.6 0.0 13.5 0.0 0.1 18.9 28.1 0.1 0.0 0.2 0.2 0.2 0.0 0.1 0.0 0.4 0.0 15.9 8.6 2.4 0.4 0.1 0.3 2.5 3.8 0.4 0.5 0.2 2.8 0.0 6.8 0.1 0.1 12.8 0.0 0.5 0.0 0.1 0.1 0.0 2.6 0.2 2.9 5.3 6.4 0.0 0.0 0.0 0.2 0.0 0.0 13.9 0.9 0.0 0.0 0.0 0.2 0.7 0.0 2.5 4.8 6.2 0.4 0.0 0.0 0.0 0.3 3.3 3.4 5.3 0.0 0.0 3.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 7.2 0.5 0.4 0.0 0.0 0.0 1.9 0.0 0.0 0.0 3.3 0.3 0.2 0.0 6.4 0.0 0.0 0.0 5.3 5.6 0.3 0.2 0.2 0.2 0.0 0.0 2.6 0.0 5.9 0.3 7.2 0.0 4.1 0.0 0.9 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 11.6 13.5 18.9 28.1 15.9 8.6 2.5 3.8 6.8 2.6 6.4 13.9 0.0 0.0 0.0 288.3 2.8 0.0 0.1 0.0 0.0 29.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.1 2.3 0.0 3.5 0.2 7.2 0.0 1353.2 0.0 0.0 0.5 1.5 0.1 0.0 10.0 0.4 0.4 0.1 62.2 1095.0 0.4 0.0 0.0 0.3 4.1 0.0 0.1 0.0 29.0 0.0 1.0 0.0 615.8 86.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.1 0.7 6.3 10.8 0.0 0.0 0.0 0.0 0.1 0.1 0.1 RHBG SLC42A2 ENSG00000132677 "Rh family B glycoprotein" Q9H310 1 156369211-156385219 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ammonia transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "kidney: 9.8" "Group enriched" "Detected in some" 4 "Granulosa cells: 89.9;Theca cells: 91.3" "Group enriched" "Detected in some" 5 "liver cancer: 14.2;renal cancer: 5.1;urothelial cancer: 4.1" "Region enriched" "Detected in single" 17 "cerebellum: 2.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "CACO-2: 2.9;Hep G2: 3.0;RT4: 5.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA042726, HPA048489" Enhanced Approved Nucleoplasm NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 15: RT4 - Unknown function" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA042726: AB_2678131, HPA048489: AB_2680417" "unprognostic (1.20e-1)" "unprognostic (2.05e-1)" "unprognostic (4.55e-3)" "unprognostic (5.04e-2)" "unprognostic (2.95e-2)" "unprognostic (3.76e-3)" "unprognostic (2.00e-1)" "unprognostic (1.19e-1)" "unprognostic (1.49e-1)" "unprognostic (2.45e-1)" "unprognostic (3.72e-1)" "unprognostic (3.63e-2)" "unprognostic (4.91e-2)" "unprognostic (1.51e-1)" "unprognostic (1.96e-1)" "unprognostic (1.91e-3)" "prognostic favorable (8.06e-4)" 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 9.8 1.9 0.0 0.0 0.1 0.0 2.1 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 22.0 0.0 0.0 0.0 0.0 19.6 0.3 10.3 0.3 0.0 0.1 0.0 0.0 0.2 0.6 0.1 1.3 0.0 0.1 0.0 89.9 0.0 10.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 12.4 0.3 0.1 0.0 0.0 0.6 1.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.1 0.1 1.3 0.2 0.0 0.0 0.0 0.8 2.3 0.4 0.0 0.4 0.0 0.0 91.3 0.0 0.1 RIBC1 FLJ32783 ENSG00000158423 "RIB43A domain with coiled-coils 1" Q8N443 X 53422690-53431120 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 27.5;testis: 39.3" "Group enriched" "Detected in many" 5 "Early spermatids: 249.1;Late spermatids: 609.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HeLa: 6.1;T-47d: 7.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA001150 Approved "Nuclear bodies" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 20: HeLa - Mitochondria" "Cluster 31: Spermatids - Spermatogenesis" "Nuclear bodies" "HPA001150: AB_2666211" "unprognostic (1.08e-2)" "prognostic favorable (1.90e-5)" "unprognostic (1.25e-1)" "prognostic favorable (9.66e-4)" "unprognostic (1.11e-1)" "unprognostic (2.39e-3)" "unprognostic (9.88e-2)" "unprognostic (3.97e-4)" "unprognostic (2.25e-2)" "unprognostic (7.89e-3)" "unprognostic (3.79e-2)" "unprognostic (4.99e-2)" "unprognostic (1.78e-1)" "unprognostic (2.07e-1)" "unprognostic (1.25e-2)" "unprognostic (1.75e-1)" "unprognostic (3.29e-1)" 0.7 3.9 3.2 0.7 3.1 0.6 1.5 2.9 3.4 2.7 10.2 1.1 0.9 2.4 2.9 0.7 27.5 1.4 1.1 3.1 3.9 3.2 0.7 3.3 0.8 7.5 6.5 2.6 1.9 2.6 6.6 0.3 4.7 1.8 0.5 11.4 2.0 1.6 0.7 1.2 0.8 0.6 5.4 0.9 0.9 39.3 3.4 1.7 3.5 0.5 0.6 0.8 0.9 4.8 1.3 3.5 1.3 0.9 0.4 0.9 0.8 0.4 0.2 0.7 0.7 1.3 2.1 1.3 2.3 0.1 2.3 2.4 0.3 0.7 0.9 0.8 2.3 0.8 6.1 0.6 0.2 0.8 1.3 0.3 0.3 2.0 0.5 1.7 0.6 1.0 0.6 1.5 0.5 0.9 1.5 0.7 1.7 0.6 0.9 1.1 0.9 1.0 2.0 0.7 2.9 0.5 3.4 1.2 0.8 4.1 7.8 0.3 0.2 0.3 1.7 1.0 0.5 1.4 1.1 0.7 1.3 0.3 0.6 0.0 0.2 0.0 0.0 0.3 0.6 0.0 0.2 0.5 0.3 0.3 0.1 0.1 0.8 1.2 0.4 0.2 0.5 0.2 3.2 3.1 2.9 3.4 3.1 3.9 7.5 6.5 4.7 5.4 3.4 4.8 0.3 0.0 0.5 1.0 0.2 1.3 2.1 3.7 1.8 2.2 1.7 2.2 1.2 2.8 6.5 0.0 4.2 0.5 0.2 0.3 1.9 1.4 249.1 73.2 1.0 0.8 1.2 0.0 0.2 0.2 0.5 0.9 0.0 1.6 2.5 0.5 0.0 0.7 0.1 1.7 0.3 0.1 10.2 0.6 0.3 609.6 2.5 0.5 1.8 0.0 0.0 5.5 0.0 0.0 0.5 0.5 0.1 1.9 0.0 0.8 0.7 7.2 71.4 11.3 0.0 1.6 1.0 14.2 6.4 0.4 0.9 0.4 0.6 2.1 0.3 0.7 RIPK3 RIP3 ENSG00000129465 "Receptor interacting serine/threonine kinase 3" Q9Y572 14 24336025-24340022 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Necrosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 38.5;Exocrine glandular cells: 35.2;Gastric mucus-secreting cells: 22.4;Paneth cells: 21.4;Proximal enterocytes: 22.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "CAPAN-2: 7.0;HDLM-2: 4.1;OE19: 10.1;SK-BR-3: 11.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 64: Macrophages - Immune response" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (1.85e-2)" "unprognostic (1.66e-1)" "unprognostic (5.16e-3)" "unprognostic (1.12e-2)" "unprognostic (1.95e-1)" "unprognostic (1.29e-1)" "unprognostic (1.19e-1)" "unprognostic (2.32e-1)" "unprognostic (3.25e-1)" "unprognostic (2.02e-1)" "unprognostic (3.31e-2)" "unprognostic (1.11e-1)" "unprognostic (5.26e-3)" "unprognostic (9.58e-2)" "unprognostic (5.58e-2)" "unprognostic (1.08e-1)" "unprognostic (2.93e-2)" 8.6 1.7 0.7 5.6 0.7 4.9 8.0 0.7 1.4 6.4 0.8 15.2 10.2 3.2 1.4 11.9 3.8 5.4 4.1 0.7 0.7 6.2 1.7 8.1 7.7 1.2 0.8 0.7 7.9 0.8 1.2 3.2 1.1 3.4 11.0 0.0 8.9 1.5 1.5 6.5 18.3 2.1 0.8 18.6 10.6 1.1 1.1 3.5 10.7 1.3 7.6 5.4 7.5 1.1 0.0 0.0 0.0 0.0 2.4 2.7 0.0 0.6 3.4 0.0 0.0 0.1 7.0 0.1 1.7 0.3 0.0 1.6 0.0 0.1 0.0 4.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.2 1.1 0.0 0.1 0.0 0.0 0.0 0.5 0.0 10.1 0.0 0.0 0.0 1.2 1.2 0.0 0.0 0.0 0.0 11.1 0.0 0.0 1.9 2.9 1.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.6 0.0 1.7 3.3 4.2 3.7 5.1 3.9 2.1 3.1 3.7 3.3 2.4 1.6 2.3 1.9 2.7 6.0 1.6 6.1 2.9 0.7 0.7 0.7 1.4 0.7 0.7 1.2 0.8 1.1 0.8 1.1 1.1 5.5 3.2 9.1 0.0 5.7 1.5 1.4 5.8 1.8 0.0 2.0 0.9 0.7 2.8 4.7 3.7 0.0 0.3 9.6 38.5 3.9 8.1 0.1 3.2 0.8 4.2 6.1 1.3 0.0 35.2 0.4 1.9 22.4 5.4 12.6 0.0 0.7 0.0 12.7 0.0 0.0 14.4 4.1 9.5 1.6 0.3 0.0 7.7 3.6 1.9 11.6 0.0 10.3 0.0 0.0 17.8 21.4 0.0 5.5 0.5 22.5 0.1 3.7 0.0 0.0 0.2 1.0 0.0 0.3 3.9 1.4 0.3 8.3 0.1 8.0 3.3 RIPK4 "ANKK2, ANKRD3, DIK, PKK, RIP4" ENSG00000183421 "Receptor interacting serine/threonine kinase 4" P57078 21 41739369-41767089 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 72.2" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 52.3;Endometrial ciliated cells: 76.5;Gastric mucus-secreting cells: 61.2;Glandular and luminal cells: 174.2;Squamous epithelial cells: 71.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 32.2;GAMG: 41.2;HaCaT: 47.5;hTCEpi: 31.4;RPTEC TERT1: 28.3;RT4: 30.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" HPA030942 Enhanced NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "HPA030942: AB_2732462" "unprognostic (8.93e-2)" "unprognostic (2.67e-1)" "unprognostic (6.32e-3)" "unprognostic (7.87e-2)" "unprognostic (1.24e-1)" "unprognostic (5.61e-2)" "unprognostic (1.30e-1)" "unprognostic (2.88e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (6.22e-5)" "prognostic unfavorable (3.48e-4)" "unprognostic (9.98e-2)" "prognostic favorable (6.52e-4)" "unprognostic (2.69e-1)" "unprognostic (2.95e-3)" "unprognostic (2.28e-1)" "unprognostic (2.78e-2)" 1.6 0.0 0.1 0.4 0.0 0.6 4.3 0.0 0.1 11.8 3.7 3.1 9.7 1.1 2.4 72.2 5.8 5.2 1.5 0.1 0.1 11.5 19.1 4.2 0.1 0.3 0.6 0.1 14.3 7.4 10.8 2.3 0.1 10.7 2.0 0.6 14.8 9.8 0.0 21.5 13.6 0.1 0.1 0.0 15.5 2.0 0.1 7.8 7.9 0.0 5.2 6.3 22.3 0.1 14.3 9.0 0.0 0.0 0.0 0.0 13.7 0.1 0.1 0.2 0.2 23.5 32.2 0.0 13.3 2.9 41.2 47.5 0.7 19.2 0.0 0.0 9.4 0.0 6.9 8.8 0.0 0.0 0.0 0.0 31.4 0.2 4.2 0.0 0.0 14.3 0.0 0.0 0.0 10.3 2.0 0.0 0.8 9.3 26.1 0.0 0.0 2.3 28.3 30.8 4.5 0.3 15.5 15.7 15.1 1.3 9.6 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.0 0.0 4.2 0.0 11.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.3 0.6 0.1 0.1 0.1 0.1 0.1 28.9 9.1 0.0 0.1 15.8 27.4 24.0 52.3 0.0 13.0 12.4 1.1 17.2 28.0 3.7 0.0 8.3 0.3 22.8 9.8 12.4 1.5 76.5 16.9 0.9 22.7 0.0 0.0 10.4 5.1 0.6 61.2 174.2 2.5 0.0 0.0 17.0 1.0 0.0 0.0 14.2 16.2 0.6 1.4 1.6 0.0 0.9 7.2 0.0 0.0 0.4 0.0 0.0 0.0 19.0 11.8 0.0 0.0 24.0 26.5 13.5 22.2 0.9 0.0 0.0 1.3 1.4 2.5 71.2 15.2 2.5 1.5 0.0 11.2 24.1 RIPOR1 "FAM65A, FLJ13725" ENSG00000039523 "RHO family interacting cell polarization regulator 1" Q6ZS17 16 67518418-67546788 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 49.2;Endothelial cells: 23.6;Hofbauer cells: 30.0;Pancreatic endocrine cells: 37.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "classical monocyte: 11.2;eosinophil: 9.3;intermediate monocyte: 15.6;memory B-cell: 15.8;myeloid DC: 10.2;naive B-cell: 9.4;neutrophil: 6.6;non-classical monocyte: 15.1;plasmacytoid DC: 14.4" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005923 Uncertain Approved "Golgi apparatus,Cytosol" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 7: Non-specific - Mitochondria" "Golgi apparatus, Cytosol" "HPA005923: AB_1078809" "unprognostic (7.41e-2)" "unprognostic (2.07e-2)" "unprognostic (1.56e-3)" "unprognostic (3.71e-2)" "unprognostic (1.11e-1)" "prognostic unfavorable (6.53e-4)" "unprognostic (1.10e-2)" "prognostic unfavorable (5.00e-5)" "unprognostic (1.45e-1)" "unprognostic (1.98e-1)" "unprognostic (3.38e-1)" "unprognostic (1.24e-1)" "prognostic favorable (5.82e-8)" "unprognostic (8.51e-2)" "unprognostic (3.52e-2)" "unprognostic (1.19e-1)" "unprognostic (7.46e-2)" 44.4 28.1 27.6 23.4 30.6 27.2 37.7 26.4 38.6 39.9 7.5 36.0 8.8 45.2 6.0 18.5 36.2 21.5 53.6 33.6 16.3 67.6 16.7 55.8 20.8 26.6 17.1 33.2 30.1 20.6 26.5 29.8 25.4 30.6 7.4 43.8 22.8 20.2 34.9 21.4 32.7 25.2 12.3 61.2 25.9 18.6 21.5 10.8 36.4 22.3 17.5 37.1 30.4 18.6 44.0 36.6 16.1 25.3 40.0 35.7 35.7 45.7 44.9 51.6 43.0 75.7 31.5 6.0 62.4 78.8 26.0 24.4 32.7 41.3 33.2 19.3 17.0 57.9 53.6 17.4 44.7 4.6 28.0 35.5 18.8 69.7 47.1 36.8 55.2 10.2 6.5 6.4 38.7 47.7 13.8 14.4 4.4 8.5 29.1 46.8 29.0 31.2 39.0 22.1 12.1 31.9 85.1 13.8 28.6 15.9 30.2 10.7 96.8 58.3 34.2 49.8 32.2 9.0 6.8 17.8 38.8 11.1 31.7 0.1 11.2 9.3 1.2 15.6 1.8 15.8 1.0 0.5 10.2 9.4 0.7 0.7 6.6 1.7 15.1 14.4 0.8 6.0 27.6 30.6 26.4 38.6 33.6 16.3 26.6 17.1 25.4 12.3 21.5 18.6 49.2 16.0 16.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 12.1 8.8 0.0 0.0 1.8 7.3 0.0 0.8 3.7 0.0 0.0 15.8 0.0 9.3 17.9 23.6 0.0 0.0 0.0 12.5 1.3 6.9 0.0 18.5 10.1 7.9 0.0 0.0 30.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 37.0 0.0 0.0 2.3 0.0 0.0 5.8 2.2 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 2.1 2.3 16.6 0.0 0.0 RLN2 "bA12D24.1.1, bA12D24.1.2, H2, RLXH2" ENSG00000107014 "Relaxin 2" P04090 9 5299864-5304716 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 5.2" "Cell type enhanced" "Detected in many" "Early spermatids: 13.0;Muller glia cells: 9.6;Spermatocytes: 17.3;Syncytiotrophoblasts: 13.5" "Group enriched" "Detected in some" 5 "breast cancer: 2.0;prostate cancer: 6.7" "Not detected" "Not detected" "Group enriched" "Detected in many" 26 "gdT-cell: 1.4;MAIT T-cell: 4.2;memory B-cell: 1.9;memory CD4 T-cell: 2.8;memory CD8 T-cell: 2.3;naive B-cell: 1.4;naive CD4 T-cell: 4.0;naive CD8 T-cell: 3.0;NK-cell: 3.5;T-reg: 1.3" "Group enriched" "Detected in many" 33 "B-cells: 1.9;NK-cells: 3.5;T-cells: 4.2" "Cell line enhanced" "Detected in some" "Daudi: 5.6;HEL: 21.9;T-47d: 6.1;U-266/84: 10.2" "Secreted to blood" NA NA 24400 10000 "Cluster 22: NK-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 36: HEL - Hemostasis" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (1.63e-3)" "unprognostic (1.26e-1)" "unprognostic (2.09e-3)" "unprognostic (2.84e-1)" "unprognostic (2.03e-2)" "unprognostic (9.99e-2)" "unprognostic (1.48e-1)" "unprognostic (2.77e-2)" "unprognostic (2.91e-3)" "unprognostic (2.50e-3)" "unprognostic (9.18e-2)" "unprognostic (1.74e-6)" "unprognostic (2.36e-1)" "unprognostic (4.71e-2)" "unprognostic (1.88e-2)" "unprognostic (8.41e-4)" 0.4 0.0 0.4 1.4 0.5 0.3 2.3 0.6 0.7 0.4 0.5 0.5 0.0 0.5 0.3 0.3 5.2 0.2 0.5 0.4 0.5 1.9 0.0 0.7 2.8 0.6 0.5 0.1 0.5 4.2 2.9 0.6 0.6 3.9 0.4 2.9 0.3 0.6 0.0 0.4 0.5 0.2 0.5 0.9 0.5 2.8 0.5 2.7 0.8 0.2 2.3 0.2 0.1 0.5 3.0 0.4 0.6 0.0 0.1 0.0 0.0 0.0 0.1 0.5 1.0 0.3 1.6 5.6 0.4 0.0 0.0 0.9 0.0 2.8 0.7 4.4 2.0 21.9 0.0 0.2 0.2 0.0 0.0 0.0 0.4 0.1 0.2 0.0 0.5 0.0 0.0 0.2 0.1 1.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.0 0.6 2.7 3.0 0.0 0.6 0.1 0.2 6.1 0.1 0.2 0.0 0.5 0.0 0.1 1.3 10.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 4.2 1.9 2.8 2.3 0.0 1.4 4.0 3.0 0.0 3.5 0.0 0.0 1.3 0.8 0.4 0.5 0.6 0.7 0.4 0.5 0.6 0.5 0.6 0.5 0.5 0.5 0.8 3.2 0.6 0.3 2.6 0.5 2.3 1.5 1.2 1.5 3.8 3.0 1.9 1.5 1.2 1.8 0.0 6.3 1.3 0.1 7.9 2.8 13.0 3.3 0.3 0.8 3.6 1.7 0.4 1.5 2.3 0.4 0.5 0.3 0.0 0.6 0.0 0.0 0.6 3.3 0.9 1.7 2.0 0.0 0.0 5.3 0.6 0.1 0.0 1.0 0.8 9.6 4.1 0.0 0.9 0.8 0.2 0.4 0.5 1.0 0.1 1.4 5.0 1.7 0.0 0.6 0.4 17.3 5.1 1.4 1.3 13.5 3.4 0.0 1.5 0.5 RNASE6 "RAD1, RNaseK6, RNS6" ENSG00000169413 "Ribonuclease A family member k6" Q93091 14 20781268-20782467 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 110.5" "Cell type enhanced" "Detected in many" "B-cells: 108.0;dendritic cells: 221.7;Hofbauer cells: 207.9;Kupffer cells: 551.2;Langerhans cells: 198.4;Macrophages: 270.3;monocytes: 115.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 1238.8" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 7 "RPMI-8226: 65.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA000698 Approved "Secreted to blood" NA NA 2600000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 41: Macrophages - Immune response" "HPA000698: AB_2181340" "unprognostic (5.04e-2)" "unprognostic (5.21e-3)" "unprognostic (3.59e-2)" "unprognostic (4.05e-2)" "unprognostic (1.74e-1)" "unprognostic (7.31e-2)" "unprognostic (7.91e-2)" "unprognostic (2.29e-1)" "unprognostic (4.45e-1)" "unprognostic (1.65e-1)" "unprognostic (2.04e-1)" "unprognostic (2.73e-1)" "unprognostic (2.85e-3)" "unprognostic (9.62e-2)" "unprognostic (5.60e-3)" "unprognostic (3.46e-2)" "unprognostic (5.54e-2)" 25.2 29.5 8.0 59.6 7.5 27.5 24.0 7.8 13.6 31.6 10.0 27.7 17.3 10.6 78.4 16.0 11.3 47.7 11.7 7.3 10.9 12.2 21.1 29.6 110.5 13.6 10.1 9.9 8.4 9.0 4.3 44.8 11.9 7.9 34.0 1.8 11.2 17.2 2.0 8.6 33.4 23.6 10.8 62.1 14.9 4.5 12.6 43.8 5.5 6.0 84.5 43.3 5.1 19.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 2.1 2.1 0.0 0.0 0.0 0.0 0.0 1.7 4.7 0.6 0.2 0.0 0.0 1.9 4.6 0.0 0.0 0.0 0.2 0.0 65.6 1.1 0.7 0.0 0.1 0.0 0.0 0.1 0.1 0.0 8.1 1.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 9.7 0.0 441.1 537.3 12.8 5.3 124.8 12.0 324.7 13.6 5.6 513.3 410.3 6.4 1.0 199.0 36.7 2.0 1238.8 1.1 329.8 8.0 7.5 7.8 13.6 7.3 10.9 13.6 10.1 11.9 10.8 12.6 19.5 1.6 6.4 7.5 0.0 108.0 4.5 0.2 0.0 1.8 0.0 1.4 2.8 0.6 14.3 1.2 0.0 0.0 1.1 221.7 2.6 0.0 0.0 0.8 0.1 0.0 3.8 0.0 12.0 0.0 0.0 1.6 1.4 1.1 0.2 0.0 0.0 8.6 3.3 207.9 0.0 0.0 0.5 2.0 551.2 198.4 4.8 2.8 270.3 21.4 1.9 115.8 0.0 9.2 0.0 0.0 0.0 12.6 0.7 52.4 0.2 0.4 0.5 0.2 0.4 13.1 0.6 0.6 0.1 0.7 0.6 3.8 2.2 7.8 0.0 3.4 1.2 RNASEH2B "AGS2, DLEU8, FLJ11712" ENSG00000136104 "Ribonuclease H2 subunit B" Q5TBB1 13 50909747-51024120 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Aicardi-Goutieres syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 132.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MOLT-4: 351.0;NB-4: 259.8;REH: 286.0;THP-1: 258.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040084, HPA041469" Approved Enhanced Nucleoplasm NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm "HPA040084: AB_10697714, HPA041469: AB_2677496" "unprognostic (4.33e-2)" "unprognostic (1.71e-1)" "unprognostic (2.80e-2)" "unprognostic (3.20e-1)" "unprognostic (2.59e-1)" "unprognostic (1.16e-1)" "unprognostic (8.33e-2)" "unprognostic (2.79e-2)" "unprognostic (2.50e-2)" "unprognostic (9.63e-3)" "unprognostic (1.13e-1)" "unprognostic (5.10e-2)" "prognostic unfavorable (2.54e-8)" "unprognostic (1.05e-1)" "unprognostic (3.13e-1)" "unprognostic (1.39e-2)" "unprognostic (3.34e-1)" 17.7 14.8 13.2 28.6 13.5 58.4 19.5 14.5 15.2 16.0 8.7 22.3 16.7 18.8 14.1 17.6 24.9 17.1 25.2 11.9 11.5 14.8 15.0 20.5 45.7 12.2 12.1 21.2 25.7 17.1 8.3 19.6 12.0 19.2 22.0 4.7 20.2 21.6 23.8 13.5 19.8 26.8 12.4 26.3 19.2 17.3 13.7 132.6 27.4 6.0 38.4 22.9 9.4 15.4 41.1 33.1 17.6 37.5 22.9 45.9 41.7 28.6 32.4 40.6 34.0 43.1 61.2 114.4 17.8 29.4 38.4 38.2 55.8 26.1 48.4 42.2 47.1 102.7 22.4 25.4 31.2 191.2 66.0 17.9 33.4 35.9 31.8 36.8 36.3 238.0 58.7 52.7 55.4 19.2 351.0 259.8 57.9 87.2 25.7 286.0 51.4 77.7 30.6 23.6 38.8 56.8 34.4 12.6 38.0 22.8 19.7 258.7 25.6 36.0 30.1 42.7 64.3 69.8 50.3 135.6 9.5 140.6 43.1 3.5 37.5 17.8 31.6 43.3 35.7 104.2 61.9 51.4 55.1 86.4 54.4 51.9 6.1 38.0 38.3 94.0 107.5 54.1 13.2 13.5 14.5 15.2 11.9 11.5 12.2 12.1 12.0 12.4 13.7 15.4 21.2 38.5 23.8 17.6 85.8 18.7 30.5 43.7 22.2 14.1 31.1 35.8 47.4 18.6 27.4 16.5 6.2 40.7 92.3 9.7 29.4 41.7 74.0 30.1 33.2 14.9 12.1 107.7 31.1 50.5 55.7 26.7 13.7 18.2 52.6 62.0 16.4 15.1 97.3 1.7 35.4 21.8 24.4 59.0 22.0 38.2 27.7 50.4 16.0 45.0 86.4 11.7 45.3 44.2 59.5 24.7 9.9 29.7 75.6 34.5 12.1 28.4 37.3 6.2 13.1 21.8 28.9 91.4 44.3 26.9 21.0 17.9 56.5 36.9 35.4 29.3 RND2 "ARHN, Rho7, RhoN" ENSG00000108830 "Rho family GTPase 2" P52198 17 43025231-43032041 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 64.2;choroid plexus: 17.8;testis: 37.2" "Cell type enriched" "Detected in many" 4 "Late spermatids: 590.2" "Group enriched" "Detected in many" 5 "glioma: 44.4;testis cancer: 11.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 12.0;AN3-CA: 15.5;HAP1: 12.1;NTERA-2: 17.2;SH-SY5Y: 10.4;SuSa: 7.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077757 Approved NA NA "Cluster 17: Basophils - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 12: NES - Nervous system development" "Cluster 31: Spermatids - Spermatogenesis" "HPA077757: AB_2732361" "unprognostic (2.19e-2)" "unprognostic (5.70e-2)" "unprognostic (1.65e-2)" "unprognostic (1.53e-1)" "unprognostic (2.02e-1)" "unprognostic (6.52e-2)" "unprognostic (2.44e-3)" "unprognostic (4.55e-2)" "unprognostic (7.44e-2)" "unprognostic (3.79e-1)" "unprognostic (1.22e-4)" "unprognostic (7.85e-2)" "unprognostic (8.17e-2)" "unprognostic (6.13e-3)" "unprognostic (9.92e-2)" "unprognostic (7.52e-2)" "unprognostic (5.57e-2)" 0.6 3.0 30.8 0.2 41.7 0.2 1.0 46.5 29.9 2.2 17.8 4.1 0.3 3.6 2.5 1.1 2.0 0.8 2.2 23.1 48.4 1.5 4.1 0.5 0.2 64.2 59.0 3.7 0.6 5.6 7.0 0.1 52.4 2.6 0.4 3.9 0.8 3.7 0.5 2.2 1.2 2.4 47.8 0.1 1.3 37.2 46.3 0.4 6.5 0.2 0.3 2.1 1.6 38.8 0.0 0.3 12.0 15.5 0.9 0.6 0.3 0.5 0.7 2.1 1.6 1.9 0.2 0.1 2.8 1.6 0.7 0.1 12.1 0.2 1.8 0.0 6.2 0.0 0.2 0.2 0.9 0.1 0.1 0.8 0.1 2.4 0.1 0.3 0.2 1.3 3.1 0.1 0.0 0.5 4.9 0.2 17.2 0.0 0.1 0.9 0.0 0.1 0.2 0.0 3.3 10.4 0.0 0.2 0.1 7.9 2.3 0.0 0.1 0.3 0.4 0.1 0.0 1.1 3.3 0.2 1.9 0.0 0.1 0.5 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 30.8 41.7 46.5 29.9 23.1 48.4 64.2 59.0 52.4 47.8 46.3 38.8 1.5 0.0 1.5 2.0 0.1 1.3 4.8 0.6 6.8 2.8 2.0 3.3 2.1 1.5 2.0 3.7 0.0 2.1 0.0 0.1 5.9 1.2 136.3 1.9 12.6 1.2 0.0 0.0 2.2 0.8 1.9 3.2 0.0 1.0 1.3 10.5 1.4 3.3 0.6 5.0 7.2 0.0 0.0 0.6 0.7 590.2 5.0 0.8 1.8 1.0 0.0 27.2 1.0 11.6 1.6 0.3 0.1 4.5 0.1 1.6 0.0 2.3 6.5 3.7 0.0 6.2 2.9 38.3 6.1 0.8 1.8 1.6 0.6 2.6 0.1 1.6 RNF11 "CGI-123, MGC51169, Sid1669p" ENSG00000123091 "Ring finger protein 11" Q9Y3C5 1 51236273-51273447 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 22.1" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045781 Uncertain NA NA "Cluster 38: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 51: Myeloid cells - Hemostasis" "HPA045781: AB_2679450" "unprognostic (2.66e-1)" "unprognostic (1.50e-1)" "unprognostic (1.02e-1)" "unprognostic (1.45e-2)" "unprognostic (8.30e-2)" "unprognostic (1.23e-1)" "unprognostic (6.92e-2)" "unprognostic (3.57e-2)" "unprognostic (3.75e-2)" "unprognostic (2.66e-1)" "unprognostic (9.04e-2)" "unprognostic (2.11e-1)" "prognostic favorable (3.14e-4)" "unprognostic (2.14e-2)" "unprognostic (1.08e-1)" "unprognostic (3.48e-1)" "unprognostic (3.92e-2)" 70.1 70.6 79.0 24.5 82.5 71.2 46.9 67.7 117.5 49.8 51.5 45.2 34.3 48.5 51.9 66.8 35.8 40.5 69.0 88.2 82.5 65.5 61.2 42.5 20.7 71.3 82.9 77.2 27.4 67.6 51.4 47.1 79.6 51.3 30.4 64.7 37.3 48.5 107.1 35.2 34.7 48.2 78.4 33.3 34.6 29.2 82.6 23.6 72.1 94.5 25.8 53.4 46.1 75.2 66.3 15.7 32.6 44.7 114.2 91.8 49.6 72.3 83.5 62.4 76.5 18.4 24.6 0.5 72.1 133.4 77.1 22.2 36.6 53.9 105.2 124.5 40.4 43.2 23.7 28.7 78.6 20.4 113.0 67.8 87.3 68.3 71.5 97.4 80.2 23.6 14.9 26.2 130.4 24.1 24.9 17.2 46.5 33.1 40.6 19.1 59.8 29.4 111.2 61.4 31.7 34.3 53.9 61.8 79.3 77.9 35.8 28.9 85.8 97.6 51.9 76.1 82.8 58.9 62.9 6.6 51.3 40.5 60.9 22.1 1.6 7.1 2.6 2.3 3.9 0.9 2.6 3.6 1.7 0.7 2.8 3.6 6.2 3.6 2.1 6.7 3.2 3.6 79.0 82.5 67.7 117.5 88.2 82.5 71.3 82.9 79.6 78.4 82.6 75.2 54.7 57.7 41.6 19.9 30.0 136.9 108.7 37.5 84.8 37.0 70.5 33.1 120.6 37.1 41.1 40.5 25.0 38.6 63.4 62.7 105.7 56.7 154.4 44.5 46.0 61.3 77.0 110.7 56.4 60.7 43.3 61.7 40.2 53.0 54.7 21.4 57.1 63.4 30.6 35.3 62.1 38.5 57.0 41.5 84.2 171.5 57.5 88.0 65.8 23.4 39.7 75.3 37.0 26.2 38.0 64.7 35.5 86.9 43.8 117.7 51.9 132.6 33.8 37.5 39.5 47.8 55.6 59.1 33.9 97.7 168.8 196.9 49.6 39.4 29.5 173.9 RNF128 "FLJ23516, GRAIL" ENSG00000133135 "Ring finger protein 128" Q8TEB7 X 106693794-106797016 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 62.1;liver: 124.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 67.3;Cholangiocytes: 50.1;Distal enterocytes: 49.3;Gastric mucus-secreting cells: 54.6;Hepatocytes: 76.9;Proximal enterocytes: 85.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 41.9;CAPAN-2: 35.0;Hep G2: 30.6;OE19: 96.2;RPTEC TERT1: 30.5;RT4: 88.8;WM-115: 53.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019675 Uncertain NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" "HPA019675: AB_2670225" "unprognostic (1.78e-1)" "unprognostic (1.44e-2)" "unprognostic (1.23e-1)" "unprognostic (1.88e-3)" "unprognostic (1.92e-4)" "unprognostic (2.14e-3)" "unprognostic (2.37e-2)" "unprognostic (1.02e-1)" "unprognostic (2.06e-1)" "unprognostic (2.43e-2)" "unprognostic (1.55e-2)" "unprognostic (1.75e-2)" "prognostic unfavorable (1.07e-7)" "unprognostic (1.11e-2)" "unprognostic (7.61e-2)" "unprognostic (6.30e-2)" "unprognostic (5.30e-3)" 0.7 35.0 2.6 1.8 2.4 0.0 7.9 1.9 2.4 0.6 0.8 21.8 62.1 0.1 0.5 4.6 1.0 33.1 0.5 2.5 4.2 31.5 124.6 14.7 0.2 2.7 2.2 2.0 16.4 0.7 6.6 11.1 3.3 2.8 19.6 0.1 28.6 2.1 8.9 6.9 60.8 0.6 1.6 0.1 46.9 0.6 4.3 2.8 29.4 4.1 0.2 20.0 2.0 1.6 11.1 0.0 0.0 0.0 3.4 1.8 41.9 0.1 0.3 0.0 0.0 18.8 35.0 0.0 0.0 0.6 0.4 13.3 0.1 0.0 0.0 0.0 20.6 0.0 0.3 30.6 0.0 0.0 0.0 0.1 14.4 0.0 0.1 2.2 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 2.4 96.2 0.3 0.0 0.1 0.1 30.5 88.8 0.2 0.0 0.0 2.3 2.2 0.3 2.3 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.0 15.1 0.0 53.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 2.4 1.9 2.4 2.5 4.2 2.7 2.2 3.3 1.6 4.3 1.6 0.1 67.3 19.6 6.2 0.5 6.8 6.6 13.1 10.2 0.0 9.7 4.2 0.5 50.1 15.0 33.1 0.0 23.4 0.1 49.3 0.0 14.7 0.1 0.0 0.0 0.3 24.7 2.7 17.9 15.6 3.3 0.3 54.6 0.0 0.0 0.1 1.8 76.9 1.9 0.0 19.6 33.3 2.0 2.7 0.4 0.2 0.0 0.4 3.6 3.7 0.0 0.0 0.0 25.1 13.8 25.6 23.6 0.0 0.0 1.9 85.4 25.3 8.7 0.0 0.0 0.0 1.3 0.0 2.0 11.5 5.3 16.6 0.2 0.5 28.7 8.5 RNF17 "FLJ11045, Mmip-2, SPATA23, TDRD4" ENSG00000132972 "Ring finger protein 17" Q9BXT8 13 24764169-24879921 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "testis: 24.3" "Group enriched" "Detected in some" 7 "Early spermatids: 22.2;Late spermatids: 27.6;Spermatocytes: 67.0;Spermatogonia: 24.3" "Cancer enriched" "Detected in single" 41 "testis cancer: 4.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 13 "olfactory bulb: 1.4" "HPA039699, HPA040111" Approved NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA039699: AB_10795254, HPA040111: AB_10795414" "unprognostic (2.57e-1)" "unprognostic (1.87e-2)" "unprognostic (1.37e-1)" "unprognostic (4.44e-1)" "unprognostic (4.26e-1)" "unprognostic (3.21e-2)" "unprognostic (1.59e-1)" "unprognostic (1.69e-1)" "unprognostic (8.61e-2)" "unprognostic (5.04e-1)" "unprognostic (3.12e-1)" "unprognostic (8.32e-2)" "unprognostic (1.22e-1)" 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.6 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 24.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 1.3 0.0 0.0 0.1 3.8 0.0 0.0 0.1 0.8 1.2 0.0 0.2 0.0 0.0 1.9 0.0 0.0 0.0 0.0 22.2 0.0 0.1 0.2 0.0 0.0 2.1 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.9 0.0 0.0 0.0 0.0 27.6 0.9 0.0 0.0 1.0 0.0 0.0 0.0 1.5 1.5 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 67.0 24.3 0.0 0.0 1.0 0.0 0.0 0.0 0.1 RNF34 "FLJ21786, RIF, RIFF" ENSG00000170633 "Ring finger protein 34" Q969K3 12 121400041-121430623 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 134.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074151 Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "Nuclear bodies" "HPA074151: AB_2686668" "unprognostic (3.54e-1)" "unprognostic (4.83e-2)" "unprognostic (1.90e-1)" "unprognostic (6.10e-2)" "unprognostic (9.92e-2)" "unprognostic (2.55e-2)" "prognostic unfavorable (6.72e-8)" "unprognostic (3.39e-1)" "unprognostic (9.99e-2)" "unprognostic (1.60e-2)" "unprognostic (5.87e-3)" "unprognostic (2.80e-2)" "prognostic unfavorable (4.63e-4)" "unprognostic (1.09e-1)" "unprognostic (3.55e-1)" "unprognostic (5.55e-3)" "prognostic favorable (3.02e-4)" 13.7 10.8 25.5 23.6 29.7 13.4 13.4 31.6 32.2 11.6 21.8 19.2 19.5 13.7 13.5 14.9 12.5 17.3 18.4 26.8 28.6 11.3 13.0 12.9 34.3 26.0 26.6 14.7 13.8 13.3 13.7 11.5 26.7 10.5 15.6 19.0 13.9 13.5 59.5 15.7 18.3 16.7 24.7 23.3 18.4 24.6 26.6 26.8 13.9 36.8 26.4 19.0 11.9 32.7 45.4 53.8 34.7 36.3 26.8 24.5 43.2 47.5 42.2 46.3 35.3 67.3 16.9 64.9 35.3 51.3 24.6 31.8 52.6 29.8 41.0 95.3 30.8 75.4 37.7 62.5 32.1 65.7 50.4 21.9 39.6 40.2 34.7 26.4 49.3 37.9 58.0 29.3 46.0 35.7 57.5 95.7 44.5 26.6 48.4 54.0 45.1 38.1 32.0 53.2 50.7 33.0 59.4 21.8 36.6 31.6 38.0 49.1 39.5 39.5 28.4 34.6 37.8 51.2 92.8 70.5 28.2 45.4 40.6 83.7 42.1 91.2 72.4 48.4 74.1 77.1 83.2 76.8 40.4 65.0 71.1 71.1 65.2 76.2 53.3 34.3 106.3 68.3 25.5 29.7 31.6 32.2 26.8 28.6 26.0 26.6 26.7 24.7 26.6 32.7 14.5 16.0 16.2 15.3 22.9 17.5 18.7 23.4 13.6 13.9 16.5 13.2 22.0 27.1 18.9 9.2 4.2 26.1 30.9 19.0 37.2 32.7 23.5 13.7 15.3 17.3 40.8 24.8 34.3 27.3 38.8 16.1 15.8 13.9 17.7 19.0 17.2 11.2 21.2 13.5 32.7 15.8 30.5 18.0 14.9 10.7 17.1 14.0 17.8 13.1 35.0 23.6 46.4 9.5 45.5 26.2 17.2 18.0 27.9 17.0 20.5 19.9 18.7 21.4 19.7 11.1 25.0 134.0 73.9 15.3 16.1 24.2 34.3 18.5 21.2 25.7 ROBO4 "ECSM4, FLJ20798, MRB" ENSG00000154133 "Roundabout guidance receptor 4" Q8WZ75 11 124883691-124898500 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Angiogenesis, Differentiation" "Developmental protein, Receptor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 7 "Adipocytes: 181.5;Endothelial cells: 119.7;Hepatic stellate cells: 148.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "HUVEC TERT2: 247.6;TIME: 224.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065212 Approved "Plasma membrane" NA NA 380000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA065212: AB_2685434" "unprognostic (2.86e-1)" "unprognostic (9.35e-2)" "unprognostic (2.67e-1)" "unprognostic (1.07e-1)" "unprognostic (3.82e-2)" "unprognostic (6.97e-2)" "prognostic favorable (4.85e-4)" "unprognostic (7.94e-2)" "unprognostic (2.27e-1)" "unprognostic (1.43e-1)" "unprognostic (1.73e-3)" "unprognostic (2.17e-1)" "unprognostic (1.17e-2)" "prognostic unfavorable (8.73e-4)" "unprognostic (1.55e-1)" "unprognostic (4.63e-1)" "unprognostic (5.15e-2)" 41.4 7.2 11.4 6.6 9.6 0.2 31.8 9.0 9.4 10.0 5.8 6.5 2.9 10.9 2.1 5.5 10.3 9.7 25.8 7.9 9.2 18.5 5.3 34.8 7.8 11.3 10.7 4.1 4.3 4.7 4.6 28.6 11.2 7.0 1.7 0.2 4.1 4.6 13.9 6.9 7.3 9.9 9.5 43.5 6.3 1.4 13.2 1.8 16.7 11.9 2.0 9.4 7.0 8.6 0.4 0.0 0.4 0.0 0.0 1.1 0.1 0.2 3.1 0.7 1.5 0.0 0.0 0.0 23.6 0.1 1.0 0.0 0.0 0.4 1.2 0.0 0.0 0.9 0.0 0.1 0.6 0.0 0.0 0.1 0.0 8.9 3.0 0.4 247.6 0.0 0.0 0.0 8.6 0.0 0.0 0.2 0.0 0.0 3.4 0.0 8.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 224.8 1.2 0.6 0.3 1.1 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 9.6 9.0 9.4 7.9 9.2 11.3 10.7 11.2 9.5 13.2 8.6 181.5 0.0 4.2 2.3 1.6 2.2 1.0 0.2 0.6 0.2 0.6 1.0 3.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.5 0.5 0.2 0.3 119.7 0.0 4.0 0.0 0.2 0.0 5.2 0.0 0.3 2.5 0.6 148.9 1.5 0.1 0.0 0.0 0.0 0.0 8.1 3.7 1.7 4.4 2.8 1.8 20.6 0.1 1.1 0.0 0.5 0.1 0.1 0.0 1.2 2.6 0.3 0.0 0.0 0.0 5.2 0.0 4.5 2.1 0.0 0.1 0.6 1.3 0.0 0.9 2.0 0.1 0.2 RORB "NR1F2, ROR-BETA, RZRB" ENSG00000198963 "RAR related orphan receptor B" Q92753 9 74497335-74693177 "Disease related genes, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Sensory transduction, Transcription, Transcription regulation, Vision" "Activator, Developmental protein, DNA-binding, Receptor" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 18.0;retina: 55.6" "Cell type enhanced" "Detected in many" "Astrocytes: 393.7;Endometrial stromal cells: 436.8;Excitatory neurons: 190.0;Horizontal cells: 1399.8;Muller glia cells: 390.7;Rod photoreceptor cells: 190.3" "Group enriched" "Detected in some" 5 "glioma: 2.1;prostate cancer: 2.3" "Region enhanced" "Detected in many" "cerebral cortex: 18.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HHSteC: 22.5;HSkMC: 12.4;JURKAT: 23.3;MOLT-4: 6.9;SH-SY5Y: 13.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008393 Uncertain Approved Nucleoplasm NA NA "Cluster 77: Retina - Visual perception" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "HPA008393: AB_1079830" "unprognostic (6.89e-3)" "unprognostic (4.06e-3)" "unprognostic (1.38e-1)" "unprognostic (3.97e-1)" "unprognostic (1.34e-1)" "unprognostic (1.05e-3)" "unprognostic (1.28e-1)" "unprognostic (1.18e-2)" "unprognostic (1.07e-1)" "unprognostic (3.07e-1)" "unprognostic (3.52e-1)" "unprognostic (5.46e-2)" "unprognostic (8.81e-8)" "unprognostic (5.97e-3)" "unprognostic (2.17e-2)" "unprognostic (2.26e-2)" "unprognostic (4.00e-2)" 1.1 3.4 0.0 0.1 1.3 0.0 0.3 0.0 18.0 9.8 0.0 0.2 0.1 3.9 0.0 0.4 0.3 1.7 1.6 3.7 0.7 0.5 0.0 0.6 0.0 0.0 0.3 0.2 0.1 0.3 1.7 2.0 0.0 4.6 0.3 55.6 0.1 5.0 0.0 0.2 0.1 0.3 0.0 0.0 0.3 0.6 0.4 0.4 0.3 0.1 0.3 0.7 0.8 5.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 22.5 0.0 0.7 12.4 0.0 0.0 0.0 0.0 0.0 23.3 0.0 3.6 0.0 0.1 6.9 0.0 0.9 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.3 13.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 1.1 0.0 0.0 0.0 0.5 3.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 18.0 3.7 0.7 0.0 0.3 0.0 0.0 0.4 5.1 0.1 0.0 4.8 393.7 0.4 1.7 0.8 0.0 6.8 156.4 0.4 0.6 14.1 0.0 0.0 0.0 120.9 0.2 2.7 0.1 0.0 0.0 6.6 11.9 436.8 4.2 0.0 0.0 190.0 0.0 0.4 10.7 0.0 6.9 1.3 0.2 0.7 0.0 0.6 1399.8 6.4 0.0 0.0 0.3 2.1 1.9 0.0 1.8 1.8 10.3 0.1 390.7 1.0 12.5 28.6 0.1 0.0 0.0 0.8 2.8 0.0 8.9 0.7 190.3 0.0 8.7 9.9 3.0 0.7 1.4 0.4 0.1 3.0 0.3 0.1 0.9 RPA2 ENSG00000117748 "Replication protein A2" P15927 1 27891524-27914746 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, DNA replication" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 162.3;Spermatogonia: 183.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016538, HPA026306, HPA026309" Supported Enhanced "Nucleoplasm,Nuclear bodies" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Nucleoplasm, Nuclear bodies" "CAB016538: AB_670974, HPA026306: AB_10598913, HPA026309: AB_10601572" "unprognostic (2.59e-1)" "prognostic favorable (4.33e-4)" "unprognostic (8.98e-2)" "unprognostic (6.89e-2)" "unprognostic (1.04e-1)" "prognostic favorable (8.12e-4)" "unprognostic (4.29e-3)" "unprognostic (2.03e-2)" "unprognostic (8.62e-3)" "unprognostic (1.68e-1)" "unprognostic (1.58e-2)" "unprognostic (2.31e-1)" "unprognostic (3.59e-2)" "unprognostic (9.13e-2)" "unprognostic (2.30e-1)" "unprognostic (2.18e-3)" "unprognostic (2.82e-2)" 28.4 25.0 33.3 39.7 35.1 40.7 43.8 33.4 42.4 32.0 37.4 26.6 18.5 33.7 43.4 32.3 49.1 30.6 39.2 34.5 36.1 32.4 31.8 28.7 75.1 33.7 33.2 52.0 21.0 40.7 31.3 30.2 33.9 28.7 30.2 43.8 24.0 31.3 72.3 40.3 26.1 30.7 36.7 42.3 25.6 63.7 34.0 53.4 52.9 63.2 67.6 30.3 24.9 36.7 60.9 57.4 86.4 68.5 59.3 52.8 57.2 106.1 70.3 130.0 113.5 80.2 72.7 148.9 69.4 41.1 48.4 55.8 126.5 60.3 122.4 121.0 126.0 174.3 73.0 71.3 30.9 229.7 115.1 24.6 33.2 123.8 62.3 40.3 59.1 133.1 196.2 127.1 75.7 63.6 163.9 105.1 181.7 115.1 122.0 115.0 128.7 74.2 49.1 65.2 78.3 75.8 123.3 47.3 100.7 68.1 50.9 71.8 36.6 32.2 73.0 186.2 76.3 105.8 251.0 135.8 81.4 213.5 64.3 322.3 97.4 290.0 279.7 80.0 304.4 272.5 252.9 257.4 112.1 232.0 287.4 282.7 100.1 294.1 106.5 172.3 255.5 435.5 33.3 35.1 33.4 42.4 34.5 36.1 33.7 33.2 33.9 36.7 34.0 36.7 26.5 22.4 15.7 10.4 64.0 21.0 28.5 47.1 16.5 28.4 25.7 27.8 29.0 24.3 30.4 22.0 2.1 95.2 77.8 10.1 35.2 35.0 49.0 14.6 18.8 27.9 13.8 39.1 8.8 20.6 67.3 34.8 7.1 15.1 60.9 33.3 26.4 16.6 51.9 8.4 8.4 14.0 71.2 31.5 27.6 22.6 41.3 34.1 37.4 7.5 86.7 100.0 95.8 9.5 14.3 29.5 10.4 46.3 32.6 19.3 11.2 23.6 28.8 34.5 32.9 48.0 24.7 162.3 183.5 20.6 22.4 55.7 59.9 33.9 19.3 20.1 RPP30 TSG15 ENSG00000148688 "Ribonuclease P/MRP subunit p30" P78346 10 90871952-90908553 "Enzymes, Plasma proteins, Predicted intracellular proteins" "rRNA processing, tRNA processing" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037578 Approved Approved "Nucleoplasm,Nucleoli,Microtubule ends,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nucleoli" "Microtubule ends, Cytosol" "HPA037578: AB_10696939" "unprognostic (1.55e-1)" "unprognostic (1.77e-3)" "unprognostic (2.35e-1)" "unprognostic (4.08e-1)" "unprognostic (5.64e-2)" "unprognostic (3.05e-2)" "unprognostic (3.80e-3)" "unprognostic (1.27e-1)" "unprognostic (2.73e-1)" "unprognostic (1.03e-1)" "unprognostic (2.27e-2)" "unprognostic (2.65e-1)" "prognostic unfavorable (1.01e-6)" "unprognostic (1.98e-1)" "unprognostic (9.84e-3)" "unprognostic (3.43e-2)" "unprognostic (2.10e-2)" 19.2 13.9 7.8 12.9 8.8 25.9 17.3 8.2 10.6 14.1 7.3 15.3 9.3 15.8 14.1 18.0 14.9 12.7 22.6 8.8 8.4 16.3 15.1 13.1 21.0 7.1 7.3 18.1 11.0 23.0 8.0 18.5 7.6 12.1 15.1 13.2 14.5 12.2 31.1 17.9 12.4 16.4 8.3 15.0 14.3 28.6 7.7 21.7 12.2 22.2 22.4 17.0 14.2 10.6 82.2 53.2 55.0 66.5 34.4 37.6 19.4 57.0 51.1 93.3 98.3 90.6 64.1 48.1 42.6 36.4 60.9 56.0 73.9 50.5 95.3 77.2 51.3 32.7 31.1 73.0 33.0 66.7 39.1 30.9 32.4 70.5 79.1 39.6 54.1 43.5 65.7 42.6 62.6 50.8 77.4 89.8 33.9 46.4 59.8 42.9 46.7 50.4 35.6 38.2 29.9 29.9 33.1 23.8 68.2 50.0 64.8 41.3 31.2 46.3 46.3 26.5 119.6 28.7 79.4 104.4 57.9 35.4 36.4 9.2 30.0 27.1 25.2 30.7 27.5 31.7 28.7 28.0 35.1 28.1 24.6 27.0 3.5 25.4 26.2 32.8 33.0 27.6 7.8 8.8 8.2 10.6 8.8 8.4 7.1 7.3 7.6 8.3 7.7 10.6 31.4 32.1 16.9 14.0 28.7 34.4 27.5 51.8 23.9 19.2 16.7 28.2 45.7 27.1 31.4 14.7 18.8 60.6 33.7 9.4 31.3 41.9 95.9 18.9 26.1 25.2 19.8 38.5 18.0 35.0 68.1 28.0 13.3 17.9 23.5 33.3 21.4 14.3 58.1 16.8 19.4 21.0 30.5 23.9 29.3 49.9 28.9 24.7 23.2 11.2 32.2 23.3 15.5 17.6 19.6 31.3 12.5 29.3 20.6 18.8 12.5 36.5 21.6 24.3 39.5 30.1 36.9 77.9 54.2 20.2 34.0 33.8 23.7 28.6 17.6 27.6 RRM1 ENSG00000167325 "Ribonucleotide reductase catalytic subunit M1" P23921 11 4094707-4138932 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA replication" "Allosteric enzyme, Oxidoreductase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 102.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022093, HPA057265, HPA064297" Enhanced Supported Cytosol NA Yes 140000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "CAB022093: , HPA057265: AB_2683386, HPA064297: AB_2685236" "unprognostic (4.47e-2)" "unprognostic (1.73e-2)" "unprognostic (1.99e-3)" "unprognostic (3.65e-1)" "unprognostic (2.83e-1)" "unprognostic (2.19e-1)" "prognostic unfavorable (1.53e-4)" "unprognostic (1.31e-2)" "unprognostic (3.43e-2)" "unprognostic (6.90e-2)" "unprognostic (1.06e-3)" "unprognostic (4.21e-2)" "unprognostic (6.88e-3)" "unprognostic (9.20e-3)" "unprognostic (6.16e-2)" "unprognostic (8.41e-2)" "unprognostic (9.93e-3)" 16.6 21.2 5.1 24.8 5.3 32.8 22.7 7.1 6.1 16.9 4.7 25.7 19.3 16.2 10.1 26.5 15.5 11.8 16.4 5.1 5.7 13.4 18.4 12.8 34.4 6.1 5.5 16.4 14.6 24.7 7.1 20.4 6.6 18.5 29.4 23.6 14.7 16.0 30.3 36.1 20.2 20.1 6.2 13.0 17.6 17.9 5.1 56.7 15.6 30.0 45.2 15.6 18.9 6.2 221.6 117.8 188.4 110.0 28.4 56.2 73.0 198.0 98.2 220.7 225.9 106.8 163.8 237.4 47.0 100.1 95.9 173.0 176.9 143.2 259.3 117.3 187.9 121.0 159.8 83.1 11.2 208.9 84.6 26.6 37.8 121.7 86.4 48.3 107.8 140.1 161.1 107.3 186.8 99.6 246.7 41.9 118.2 152.2 119.2 196.1 147.0 84.3 59.4 61.8 159.8 88.1 175.1 104.8 30.0 75.8 102.8 71.4 62.3 203.4 106.0 206.9 147.4 70.3 103.5 252.5 114.1 137.6 130.3 8.3 4.0 4.5 11.3 11.2 21.1 9.2 22.3 16.6 7.3 5.2 17.2 15.0 0.0 10.5 15.6 4.4 41.7 10.3 5.1 5.3 7.1 6.1 5.1 5.7 6.1 5.5 6.6 6.2 5.1 6.2 12.4 19.2 14.4 4.9 17.0 33.4 26.8 31.0 17.6 15.6 15.1 14.4 33.5 14.3 24.7 18.4 6.2 62.8 14.9 13.3 7.9 25.6 69.9 11.5 14.5 15.7 18.0 81.2 11.2 22.2 62.5 22.0 20.4 13.9 7.0 27.3 10.8 15.0 28.3 18.5 12.0 25.0 16.2 11.7 10.3 83.9 13.1 13.9 10.6 6.5 10.7 24.0 5.2 12.1 11.9 15.8 10.4 16.6 31.3 10.1 12.5 8.4 15.5 22.7 13.1 19.5 27.1 102.8 63.1 36.5 29.0 39.7 23.2 18.1 34.3 20.6 RRM2 "C2orf48, FLJ25102" ENSG00000171848 "Ribonucleotide reductase regulatory subunit M2" P31350 2 10120698-10211725 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "DNA replication" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 44.2;esophagus: 18.4;intestine: 19.7;lymphoid tissue: 58.1" "Group enriched" "Detected in many" 4 "Erythroid cells: 214.0;Extravillous trophoblasts: 254.1;Plasma cells: 248.0" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056994 Enhanced Supported Cytosol Yes Yes 13000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA056994: AB_2683304" "unprognostic (2.10e-2)" "unprognostic (1.62e-1)" "unprognostic (6.40e-3)" "unprognostic (4.42e-3)" "unprognostic (5.70e-2)" "unprognostic (1.69e-1)" "prognostic unfavorable (1.39e-5)" "unprognostic (1.04e-3)" "unprognostic (6.67e-3)" "unprognostic (4.53e-2)" "prognostic unfavorable (1.62e-4)" "unprognostic (5.11e-3)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.05e-2)" "unprognostic (2.24e-1)" "unprognostic (1.38e-1)" "unprognostic (2.09e-2)" 1.5 1.3 0.3 12.4 0.3 44.2 2.9 0.5 0.4 3.0 1.9 14.2 9.4 2.2 0.7 18.4 0.8 1.1 0.5 0.3 0.3 0.9 3.2 2.4 35.5 0.4 0.4 0.3 1.1 0.3 0.2 4.6 0.4 0.9 19.7 0.2 2.1 0.5 0.1 3.7 7.5 6.1 0.3 11.1 6.0 2.9 0.8 58.1 0.9 0.1 37.6 6.0 4.6 0.5 110.2 25.0 127.1 49.9 7.4 22.5 116.8 209.2 128.6 170.2 187.9 70.8 59.1 114.4 9.5 88.6 151.1 55.0 188.0 136.6 198.0 210.7 41.8 146.3 52.1 105.1 0.8 146.7 87.4 8.1 3.4 234.6 16.2 27.7 103.3 110.4 63.4 328.6 214.3 57.1 167.3 90.9 83.0 133.3 103.6 87.6 187.0 67.8 87.1 62.7 67.7 56.2 198.0 116.6 17.3 51.8 69.2 31.4 57.6 93.1 125.1 66.9 289.6 212.1 184.9 195.9 51.0 134.4 107.7 0.3 0.1 0.1 1.2 0.0 0.0 0.1 0.3 0.8 0.1 0.1 0.1 0.4 0.4 0.8 0.0 0.1 0.2 0.2 0.3 0.3 0.5 0.4 0.3 0.3 0.4 0.4 0.4 0.3 0.8 0.5 0.2 3.2 1.5 0.0 25.0 10.5 3.0 9.2 1.2 0.0 3.9 4.4 1.4 1.5 2.3 0.0 0.0 42.3 5.6 12.9 1.9 1.2 3.9 2.2 3.5 4.2 0.0 214.0 0.1 0.0 254.1 11.2 11.7 3.6 5.7 12.2 3.9 3.7 47.9 0.0 0.0 26.9 2.0 7.2 8.8 6.8 0.3 5.0 0.0 1.0 0.0 0.0 7.2 0.0 0.0 0.5 0.3 0.4 248.0 1.5 2.4 2.1 4.6 0.0 0.0 0.2 14.6 22.9 34.0 51.5 1.6 48.7 11.9 1.2 36.7 5.6 RSBN1 "FLJ11220, ROSBIN" ENSG00000081019 "Round spermatid basic protein 1" Q5VWQ0 1 113761832-113812476 "Predicted intracellular proteins" "Chromatin regulator, Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042124, HPA049484" Approved Supported "Nucleoplasm,Nuclear bodies,Vesicles" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 14: REH - Unknown function" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "Nuclear bodies, Vesicles" "HPA042124: AB_10794644, HPA049484: AB_2680787" "unprognostic (3.26e-2)" "unprognostic (1.32e-1)" "unprognostic (1.15e-3)" "unprognostic (2.13e-1)" "unprognostic (3.66e-2)" "unprognostic (2.30e-2)" "unprognostic (5.06e-2)" "unprognostic (6.60e-2)" "unprognostic (1.06e-1)" "unprognostic (1.97e-2)" "unprognostic (1.56e-1)" "unprognostic (3.96e-1)" "unprognostic (1.51e-2)" "unprognostic (4.67e-2)" "unprognostic (1.43e-1)" "unprognostic (1.24e-1)" "unprognostic (1.15e-3)" 6.4 6.0 4.6 7.7 4.7 34.4 8.2 12.7 6.1 7.9 2.8 8.4 6.2 10.3 6.5 7.3 7.9 6.4 5.2 4.2 5.3 8.0 6.4 7.5 10.6 3.1 3.7 14.2 11.0 11.0 5.1 6.6 3.2 7.9 8.6 13.7 6.8 6.9 8.0 7.5 7.5 7.0 3.9 9.2 6.8 10.7 4.3 12.3 9.0 7.9 10.5 6.4 5.5 5.2 14.6 4.1 13.7 8.2 8.0 9.2 6.6 5.1 10.9 10.1 10.5 4.9 4.3 12.7 7.9 6.3 4.6 6.2 9.8 6.2 16.4 12.3 7.1 9.6 4.4 5.6 6.0 18.1 9.9 7.0 6.7 8.6 8.2 8.6 8.1 14.0 14.7 7.7 7.5 14.9 14.7 10.8 11.6 4.6 6.9 26.3 13.4 6.6 6.0 6.2 13.8 11.0 9.7 9.4 8.7 6.8 4.5 12.1 9.7 9.0 9.7 13.5 8.3 10.3 8.2 15.9 9.3 10.9 15.4 53.3 14.5 25.6 29.1 11.7 29.3 32.2 31.2 27.2 12.8 33.1 31.9 26.2 29.0 25.4 13.4 27.3 30.6 12.6 4.6 4.7 12.7 6.1 4.2 5.3 3.1 3.7 3.2 3.9 4.3 5.2 37.4 35.3 20.1 16.0 52.7 74.7 39.2 26.9 45.5 90.0 35.0 46.7 21.5 24.3 29.6 25.8 66.7 26.3 68.0 55.5 19.6 22.3 25.6 26.2 39.4 38.9 49.4 37.5 34.3 26.0 24.1 41.5 17.9 28.8 36.1 23.4 32.5 18.7 19.2 97.6 34.2 58.5 28.5 26.3 37.7 9.0 50.4 25.7 40.9 30.9 35.0 56.7 62.8 33.7 34.6 21.2 54.0 49.7 34.7 44.3 40.2 17.2 27.8 106.5 39.5 43.8 54.9 96.8 37.0 34.3 65.1 31.5 84.8 24.2 52.7 37.8 RTF2 "C20orf43, CDAO5, HSPC164, RTFDC1" ENSG00000022277 "Replication termination factor 2" Q9BY42 20 56468585-56519449 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 162.8;Distal tubular cells: 156.5;Proximal tubular cells: 149.9;Syncytiotrophoblasts: 182.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053986 Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Nucleoli" "HPA053986: AB_2682333" "unprognostic (1.65e-1)" "unprognostic (1.94e-3)" "unprognostic (2.01e-1)" "prognostic unfavorable (6.35e-4)" "unprognostic (3.54e-2)" "unprognostic (3.97e-2)" "prognostic unfavorable (1.31e-4)" "unprognostic (8.90e-2)" "unprognostic (4.02e-3)" "unprognostic (1.16e-1)" "unprognostic (8.98e-2)" "unprognostic (3.66e-2)" "unprognostic (1.55e-2)" "unprognostic (1.55e-1)" "unprognostic (1.96e-1)" "unprognostic (4.58e-1)" "unprognostic (8.48e-3)" 73.8 72.7 101.4 65.9 113.3 128.5 65.7 117.4 106.7 66.2 88.3 79.2 60.5 70.6 48.9 64.2 64.8 49.2 85.9 97.2 106.7 68.7 63.8 58.1 70.7 113.7 109.6 71.1 59.3 63.0 67.8 55.4 115.0 58.2 54.2 61.3 51.2 62.2 181.4 69.6 60.8 65.4 111.1 67.8 59.3 57.0 108.4 79.2 60.6 111.1 76.2 73.8 57.5 123.5 132.8 93.3 91.1 91.3 111.1 97.9 85.9 198.5 148.1 280.0 158.5 192.6 125.2 110.4 232.0 161.5 139.7 144.9 92.4 153.8 190.7 52.6 72.9 138.9 97.4 150.8 127.9 201.3 186.6 88.1 156.5 126.0 106.9 119.7 121.3 118.1 109.6 114.3 139.1 253.9 171.6 173.0 68.8 185.2 175.9 116.3 247.2 149.5 119.1 86.1 95.1 103.1 208.2 355.0 199.0 66.7 165.0 191.7 131.5 242.2 156.0 133.0 165.1 94.6 116.1 156.9 190.7 134.7 135.1 309.4 205.4 562.3 125.6 192.8 106.2 115.7 106.4 122.5 223.6 134.0 119.7 110.6 580.4 197.4 200.5 189.6 152.2 254.1 101.4 113.3 117.4 106.7 97.2 106.7 113.7 109.6 115.0 111.1 108.4 123.5 87.2 51.3 61.2 0.0 20.9 0.0 0.0 0.0 0.0 0.0 54.1 56.9 0.0 0.0 34.0 66.2 0.0 162.8 50.9 0.0 156.5 104.5 0.0 47.8 51.2 38.8 0.0 0.0 0.0 96.3 109.5 37.3 0.0 47.7 90.8 57.9 0.0 0.0 110.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 49.8 0.0 0.0 92.0 0.0 0.0 0.0 0.0 101.9 0.0 0.0 5.3 0.0 0.0 149.9 34.2 0.0 0.0 0.0 37.4 0.0 0.0 0.0 0.0 182.9 26.4 89.8 0.0 0.0 RTL5 "KIAA2001, Mar5, Mart5, RGAG4, SIRH8" ENSG00000242732 "Retrotransposon Gag like 5" Q5HYW3 X 72127110-72131901 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 7.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 3.6;Breast myoepithelial cells: 5.0;Endometrial ciliated cells: 3.8;Endometrial stromal cells: 8.9;Theca cells: 7.0" "Cancer enhanced" "Detected in all" "thyroid cancer: 13.4" "Region enhanced" "Detected in many" "cerebellum: 3.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 3.7;AN3-CA: 4.2;SCLC-21H: 5.0;SH-SY5Y: 7.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003652 Approved Approved Nucleoplasm NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA003652: AB_1079805" "unprognostic (7.97e-2)" "unprognostic (1.31e-2)" "unprognostic (5.29e-3)" "unprognostic (2.98e-2)" "unprognostic (3.93e-2)" "unprognostic (3.64e-1)" "unprognostic (4.20e-1)" "prognostic favorable (7.30e-4)" "unprognostic (1.62e-1)" "unprognostic (2.82e-1)" "prognostic favorable (3.41e-4)" "unprognostic (4.23e-1)" "unprognostic (4.18e-3)" "unprognostic (3.19e-2)" "unprognostic (5.58e-2)" "unprognostic (1.35e-1)" "unprognostic (1.79e-2)" 1.3 1.3 1.0 0.3 1.0 0.2 1.2 3.4 0.8 2.3 1.8 2.2 0.4 2.6 2.0 0.5 2.2 1.1 0.8 0.5 1.2 1.4 0.8 1.4 0.3 0.1 0.0 2.8 0.6 1.1 7.2 1.0 0.2 1.5 0.4 0.7 0.8 1.3 0.3 0.4 1.0 1.2 0.0 0.8 1.9 1.4 1.2 0.1 3.8 0.4 0.1 1.7 1.5 0.1 0.0 0.1 3.7 4.2 0.9 1.1 0.2 1.4 0.5 0.2 0.5 0.2 0.0 0.0 0.6 0.3 0.6 0.0 0.8 0.1 0.7 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.4 2.2 0.0 0.6 0.0 1.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5.0 7.0 0.2 0.0 0.0 1.5 0.1 0.0 0.4 0.5 0.4 0.9 0.0 0.1 0.0 0.0 0.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.0 3.4 0.8 0.5 1.2 0.1 0.0 0.2 0.0 1.2 0.1 2.9 3.2 3.6 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.6 5.0 0.0 0.0 1.8 0.0 0.0 0.1 2.7 0.0 1.9 0.1 0.0 3.8 8.9 0.6 0.0 0.0 0.0 0.0 0.4 2.0 0.0 2.3 2.5 0.9 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.2 0.0 0.0 0.1 2.2 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.3 1.1 7.0 0.0 0.0 RUNDC1 DKFZp761H0421 ENSG00000198863 "RUN domain containing 1" Q96C34 17 42980565-42993690 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023726 Uncertain Approved "Nuclear speckles,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 11: Alveolar cells - Smell perception" "Nuclear speckles" Cytosol "HPA023726: AB_2184078" "unprognostic (4.24e-2)" "unprognostic (1.26e-1)" "unprognostic (9.39e-2)" "prognostic favorable (6.93e-5)" "unprognostic (9.78e-2)" "unprognostic (1.22e-1)" "unprognostic (6.40e-2)" "unprognostic (1.71e-1)" "unprognostic (2.59e-1)" "unprognostic (2.91e-2)" "unprognostic (3.84e-2)" "unprognostic (1.22e-1)" "unprognostic (1.53e-3)" "unprognostic (2.87e-3)" "unprognostic (1.25e-1)" "unprognostic (1.12e-2)" "unprognostic (4.77e-3)" 5.5 8.0 8.7 6.6 11.0 6.8 10.0 6.5 11.0 8.6 9.7 9.4 6.5 8.7 12.1 6.6 14.5 6.1 7.3 9.6 8.8 8.4 5.0 6.9 7.2 6.3 6.8 5.0 7.9 12.0 9.4 4.8 6.2 12.1 7.6 8.5 7.5 8.5 11.6 7.1 7.8 8.6 5.8 8.1 10.1 6.8 7.9 6.7 10.2 9.0 7.7 8.4 6.2 8.2 12.9 22.1 8.8 11.9 14.7 8.8 9.3 12.2 12.6 17.1 12.7 14.0 7.2 8.6 10.7 12.1 11.6 15.8 11.3 12.3 18.9 9.7 17.7 5.8 12.8 13.5 9.4 12.6 11.9 6.6 14.7 15.1 10.0 13.6 9.2 9.3 11.2 5.3 9.9 9.3 15.6 8.9 9.9 18.3 13.8 11.2 12.3 8.6 14.3 17.0 12.8 11.8 9.6 9.0 10.2 12.9 17.5 13.9 7.6 15.4 9.6 9.2 14.7 12.6 13.1 7.5 11.0 6.6 9.8 4.7 2.3 7.9 1.3 3.8 1.7 3.7 1.6 1.1 1.8 3.7 1.6 1.7 5.4 1.1 2.8 5.6 2.0 1.0 8.7 11.0 6.5 11.0 9.6 8.8 6.3 6.8 6.2 5.8 7.9 8.2 5.3 44.8 38.4 6.5 18.7 15.0 11.0 5.8 9.1 18.9 19.2 9.8 13.7 22.8 17.2 5.5 22.9 9.8 19.1 28.7 21.5 11.8 8.1 26.4 9.6 10.3 19.2 5.7 13.8 9.8 7.3 8.6 20.4 19.5 11.4 8.4 10.4 6.1 8.4 38.7 11.0 16.9 6.1 10.5 14.7 4.5 9.9 9.5 3.6 7.5 14.3 14.3 12.3 5.0 6.2 10.1 16.4 14.3 11.7 16.6 15.1 12.8 24.7 33.2 19.7 8.5 9.6 22.9 14.9 7.2 14.6 5.5 13.9 10.4 17.8 17.0 RUSC2 KIAA0375 ENSG00000198853 "RUN and SH3 domain containing 2" Q8N2Y8 9 35490111-35561898 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 33.6;Excitatory neurons: 61.5;Inhibitory neurons: 63.5;Microglial cells: 43.1;Oligodendrocyte precursor cells: 52.3;Oligodendrocytes: 38.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "basophil: 3.1" "Lineage enriched" "Detected in single" 4 "granulocytes: 3.1" "Cell line enhanced" "Detected in many" "TIME: 49.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021297 Uncertain NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 47: Non-specific - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA021297: AB_1856510" "unprognostic (4.67e-1)" "unprognostic (1.04e-1)" "unprognostic (1.22e-2)" "unprognostic (1.32e-3)" "unprognostic (3.46e-1)" "unprognostic (2.36e-1)" "unprognostic (1.24e-2)" "unprognostic (6.13e-2)" "unprognostic (3.88e-1)" "unprognostic (1.66e-2)" "unprognostic (1.45e-2)" "unprognostic (6.62e-3)" "unprognostic (2.46e-2)" "unprognostic (4.56e-2)" "unprognostic (2.01e-1)" "unprognostic (2.94e-2)" "unprognostic (9.38e-3)" 21.0 17.9 28.0 5.9 30.6 5.8 16.7 17.9 40.2 22.0 3.0 34.3 5.1 22.1 5.6 12.5 18.7 9.3 25.9 29.7 17.3 17.6 11.9 16.8 2.8 19.5 16.4 18.9 13.0 7.0 21.7 8.0 19.9 18.5 3.9 12.2 12.2 15.3 45.2 12.9 9.3 15.1 11.4 12.1 14.8 22.4 19.7 1.5 18.1 36.1 2.0 32.3 16.1 30.5 12.2 18.4 6.6 6.4 17.6 15.9 7.3 35.5 21.7 16.3 14.4 5.4 4.8 0.0 11.8 29.5 44.3 2.4 6.0 11.1 7.2 0.0 5.2 2.2 30.7 4.2 25.5 0.0 31.3 13.9 5.9 28.4 28.2 26.4 17.5 4.9 5.2 0.1 27.5 3.6 1.1 0.8 5.0 0.1 8.4 7.4 4.6 0.1 10.4 1.3 1.6 11.1 8.3 16.6 6.7 9.2 10.4 4.3 49.3 25.1 17.0 22.3 18.4 0.3 0.6 0.0 24.8 6.9 17.1 3.1 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 28.0 30.6 17.9 40.2 29.7 17.3 19.5 16.4 19.9 11.4 19.7 30.5 7.7 6.4 4.8 33.6 0.0 2.7 3.6 1.6 4.6 15.2 2.2 3.2 6.1 8.6 2.4 7.3 14.6 0.8 0.2 0.1 1.9 7.8 8.7 1.4 4.4 10.4 0.0 1.3 61.5 6.7 6.1 7.8 1.1 3.2 5.7 3.0 5.3 2.1 2.4 13.5 63.5 0.2 0.0 2.2 3.2 3.5 8.7 2.6 5.4 43.1 0.4 6.9 0.0 52.3 38.7 8.4 0.0 7.5 0.3 4.3 0.4 3.1 3.0 7.5 0.0 5.0 10.0 9.5 2.6 0.8 1.7 0.7 0.4 1.3 0.7 1.4 RXYLT1 "HP10481, TMEM5" ENSG00000118600 "Ribitol xylosyltransferase 1" Q9Y2B1 12 63779842-63809562 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Transferase "Congenital muscular dystrophy, Disease variant, Dystroglycanopathy, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 37.2;Endometrial stromal cells: 34.5;Extravillous trophoblasts: 33.8;Syncytiotrophoblasts: 37.1;Theca cells: 45.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064014 Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Golgi apparatus" "HPA064014: AB_2685176" "unprognostic (1.19e-1)" "unprognostic (3.28e-1)" "unprognostic (2.15e-2)" "unprognostic (3.58e-1)" "unprognostic (1.33e-1)" "unprognostic (1.16e-1)" "prognostic unfavorable (5.24e-5)" "unprognostic (1.47e-2)" "unprognostic (2.09e-3)" "unprognostic (3.17e-1)" "unprognostic (7.03e-2)" "unprognostic (1.39e-1)" "unprognostic (9.33e-2)" "unprognostic (5.27e-2)" "unprognostic (2.29e-2)" "unprognostic (1.14e-1)" "unprognostic (5.96e-2)" 6.6 12.0 6.9 4.9 7.6 4.4 10.8 7.1 8.5 7.1 7.2 6.9 5.7 6.7 15.3 5.6 7.9 5.5 14.3 6.8 7.9 10.9 8.5 5.2 7.4 7.5 7.0 12.0 11.8 15.4 9.0 5.7 7.7 8.4 7.5 9.9 8.3 7.0 10.7 8.3 4.2 6.1 7.5 5.7 5.5 11.8 7.3 7.3 12.8 8.7 7.2 7.4 5.5 9.3 9.6 19.9 14.2 11.7 12.2 16.4 13.5 10.4 18.5 17.7 11.9 6.6 10.1 20.5 17.7 13.4 14.2 9.3 17.5 16.0 22.3 18.5 13.4 11.5 5.1 12.2 18.1 17.6 10.0 14.6 15.6 17.1 22.6 16.8 10.4 16.5 14.0 19.8 27.8 18.3 10.2 8.1 8.1 10.4 20.6 9.0 14.8 13.1 17.8 15.1 30.7 5.9 10.4 9.5 24.5 9.0 20.2 9.9 10.1 14.9 15.2 9.7 15.4 10.6 17.9 15.6 10.9 11.4 20.9 0.8 1.7 1.0 1.9 1.6 3.5 3.0 2.4 2.6 1.7 2.2 2.8 2.6 0.3 3.0 2.2 4.1 4.3 1.2 6.9 7.6 7.1 8.5 6.8 7.9 7.5 7.0 7.7 7.5 7.3 9.3 17.5 9.6 8.4 0.0 7.3 0.0 0.0 0.0 0.0 0.0 26.8 26.8 0.0 0.0 10.5 16.5 0.0 24.7 6.9 0.0 37.2 23.1 0.0 28.6 34.5 8.1 0.0 0.0 0.0 30.7 33.8 12.1 0.0 16.6 7.6 15.5 0.0 0.0 15.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 8.3 0.0 0.0 0.0 0.0 17.3 0.0 0.0 2.4 0.0 0.0 30.3 13.8 0.0 0.0 0.0 14.0 0.0 0.0 0.0 0.0 37.1 4.8 45.0 0.0 0.0 S100A7A "S100A15, S100A7f, S100A7L1" ENSG00000184330 "S100 calcium binding protein A7A" Q86SG5 1 153416520-153423222 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "esophagus: 5.6;lymphoid tissue: 5.9;skin 1: 1.6;vagina: 2.7" "Group enriched" "Detected in some" 8 "Early spermatids: 2.8;Late spermatids: 3.0;Suprabasal keratinocytes: 1.8" "Group enriched" "Detected in many" 4 "head and neck cancer: 25.6;melanoma: 12.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA006997 Supported Uncertain Cytosol NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "HPA006997: AB_1079860" "unprognostic (2.18e-1)" "unprognostic (1.26e-1)" "unprognostic (3.73e-2)" "unprognostic (4.65e-2)" "unprognostic (1.40e-1)" "unprognostic (1.77e-1)" "unprognostic (1.17e-1)" "unprognostic (4.40e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 5.9 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 1.8 0.0 0.0 0.0 0.0 0.0 SALL1 "Hsal1, TBS, ZNF794" ENSG00000103449 "Spalt like transcription factor 1" Q9NSC2 16 51135975-51151367 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" Deafness "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 41.0;kidney: 36.4;liver: 36.5" "Cell type enhanced" "Detected in some" "Astrocytes: 15.3;Cone photoreceptor cells: 25.0;Endometrial stromal cells: 17.5;Glandular and luminal cells: 14.3;Hepatocytes: 30.1;Microglial cells: 26.2;Oligodendrocytes: 47.6;Proximal tubular cells: 20.3" "Cancer enhanced" "Detected in many" "glioma: 19.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 29.5;BJ hTERT+: 25.3;NTERA-2: 48.0;RPTEC TERT1: 40.4;U-87 MG: 46.2" "Region enhanced" "Detected in all" "olfactory bulb: 52.6" "Low region specificity" "Detected in all" "HPA049829, HPA074673" Enhanced Approved "Nucleoplasm,Nucleoli,Nuclear speckles,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 21: Non-specific - Transcription" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Nucleoli, Nuclear speckles, Cytosol" "HPA049829: AB_2680902, HPA074673: " "unprognostic (9.91e-2)" "unprognostic (9.42e-2)" "unprognostic (1.82e-6)" "prognostic favorable (1.28e-4)" "unprognostic (2.55e-1)" "unprognostic (1.17e-1)" "unprognostic (1.96e-2)" "unprognostic (4.41e-3)" "unprognostic (1.71e-2)" "unprognostic (2.88e-1)" "unprognostic (1.48e-1)" "unprognostic (3.96e-1)" "prognostic favorable (1.91e-7)" "unprognostic (1.86e-1)" "unprognostic (2.14e-1)" "unprognostic (3.03e-2)" "unprognostic (1.76e-1)" 0.3 0.0 18.0 0.6 29.2 0.1 0.3 29.7 21.3 19.6 2.1 2.6 1.0 17.4 0.0 0.3 11.0 0.4 0.8 17.9 21.7 36.4 36.5 0.0 0.0 41.0 32.2 4.5 1.0 6.5 6.5 3.9 36.6 0.8 2.6 4.6 0.2 1.6 0.0 0.2 1.3 8.4 31.1 0.0 2.5 1.7 26.6 0.1 23.7 0.2 0.0 2.8 7.2 40.2 0.0 1.7 29.5 0.2 0.8 0.6 0.0 10.0 25.3 0.6 1.4 0.0 0.0 0.0 11.2 14.1 8.8 0.0 18.6 0.0 0.9 0.0 11.3 0.0 0.0 18.5 0.7 0.0 8.1 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 48.0 0.0 0.0 3.8 1.9 0.0 40.4 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 46.2 0.0 10.0 0.2 0.6 0.5 0.1 0.4 0.1 0.2 0.2 0.1 0.4 0.2 0.1 0.1 0.3 0.0 0.3 0.4 0.2 0.3 18.0 29.2 29.7 21.3 17.9 21.7 41.0 32.2 36.6 31.1 26.6 40.2 0.0 0.0 0.0 15.3 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.1 1.4 10.0 0.0 9.2 25.0 0.0 0.0 0.0 11.7 0.5 0.7 8.9 17.5 0.9 0.0 2.7 0.2 0.0 0.0 1.6 0.0 14.3 0.0 0.0 0.7 30.1 0.1 0.0 8.2 0.0 0.0 1.0 0.3 0.1 0.0 0.4 0.0 26.2 0.0 0.5 0.0 5.0 47.6 0.0 0.0 0.0 0.0 0.0 0.0 20.3 0.0 1.0 0.0 0.0 0.5 0.2 2.3 0.0 0.1 0.0 0.3 0.6 0.0 0.1 SALL3 ZNF796 ENSG00000256463 "Spalt like transcription factor 3" Q9BXA9 18 78980275-79002677 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.4;prostate: 6.0;vagina: 8.0" "Cell type enhanced" "Detected in some" "Astrocytes: 25.5;Bipolar cells: 14.7;Cone photoreceptor cells: 47.9;Horizontal cells: 25.2;Oligodendrocyte precursor cells: 21.1" "Cancer enriched" "Detected in some" 6 "glioma: 6.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 4.7;HEK 293: 2.7;NTERA-2: 9.5;SuSa: 1.6" "Region enriched" "Detected in many" 4 "olfactory bulb: 12.5" "Low region specificity" "Detected in many" HPA016656 Uncertain NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 62: Horizontal cells - Visual perception" "HPA016656: AB_1856546" "unprognostic (3.96e-2)" "unprognostic (3.41e-3)" "unprognostic (8.16e-2)" "unprognostic (1.87e-2)" "unprognostic (2.37e-1)" "unprognostic (4.23e-1)" "unprognostic (2.12e-1)" "unprognostic (1.11e-1)" "unprognostic (3.22e-1)" "unprognostic (5.86e-3)" 0.0 0.0 5.7 0.0 6.2 0.0 0.0 5.8 5.7 1.0 3.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.9 5.2 8.2 3.3 0.0 0.0 0.0 9.0 6.5 0.0 0.0 0.0 1.2 0.0 7.2 6.0 0.0 1.8 0.7 0.1 0.0 0.0 0.0 0.0 9.4 0.0 0.0 1.3 6.3 0.0 0.0 0.0 0.0 0.4 8.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 4.7 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 6.2 5.8 5.7 5.2 8.2 9.0 6.5 7.2 9.4 6.3 7.5 0.2 0.0 0.0 25.5 0.0 0.0 7.4 0.0 0.0 14.7 0.0 0.1 1.8 0.0 0.0 1.8 47.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 25.2 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.1 4.8 0.0 0.0 0.0 0.0 8.4 0.0 0.1 0.0 1.8 6.6 0.0 0.2 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 6.3 SALL4 "dJ1112F19.1, ZNF797" ENSG00000101115 "Spalt like transcription factor 4" Q9UJQ4 20 51782331-51802521 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Disease variant, Oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 3.9;thyroid gland: 5.8" "Cell type enriched" "Detected in some" 4 "Horizontal cells: 26.9" "Cancer enriched" "Detected in many" 11 "testis cancer: 22.7" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 9 "NK-cell: 2.5" "Lineage enriched" "Detected in single" 9 "NK-cells: 2.5" "Cell line enhanced" "Detected in some" "AF22: 25.0;AN3-CA: 17.5;BEWO: 33.2;NTERA-2: 60.2;SiHa: 15.6;SuSa: 39.7" "Not detected" "Not detected" "HPA015291, HPA015791" Enhanced Enhanced Nucleoplasm Yes No "Cluster 15: NK-cells - Transcription" "Cluster 1: Thyroid gland - Transcription" "Cluster 5: NTERA-2 - Transcription" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "HPA015291: AB_1856548, HPA015791: AB_1856547" "unprognostic (1.30e-1)" "unprognostic (2.35e-2)" "unprognostic (1.11e-1)" "unprognostic (1.09e-3)" "unprognostic (3.55e-2)" "unprognostic (7.43e-2)" "unprognostic (3.63e-2)" "unprognostic (1.47e-1)" "unprognostic (1.20e-1)" "unprognostic (9.23e-2)" "unprognostic (2.50e-2)" "unprognostic (2.39e-2)" "unprognostic (2.42e-8)" "unprognostic (5.90e-3)" "unprognostic (1.82e-1)" "unprognostic (5.00e-5)" "unprognostic (7.41e-2)" 0.2 0.3 0.2 0.2 0.2 0.8 0.2 0.4 0.2 0.2 0.3 0.2 0.1 0.2 0.4 0.2 0.2 0.0 0.1 0.2 0.4 0.8 1.6 0.2 0.1 0.2 0.3 0.1 2.1 2.0 0.5 0.2 0.2 2.4 0.2 0.5 0.9 0.2 0.1 0.2 0.4 0.1 0.2 0.5 0.2 3.9 0.3 0.0 5.8 0.0 0.1 0.4 0.1 0.4 0.0 1.7 25.0 17.5 0.0 0.1 33.2 0.0 0.2 0.1 0.3 9.0 0.2 0.0 0.3 0.3 0.3 4.3 0.2 0.1 0.3 0.4 0.0 0.0 7.0 0.4 0.1 0.0 1.9 0.7 0.5 0.1 0.1 0.0 0.4 0.0 0.0 0.1 0.0 1.8 0.0 0.1 60.2 0.2 0.4 2.3 0.0 0.0 0.0 0.5 5.7 3.1 15.6 0.1 1.5 39.7 0.1 1.0 0.0 0.9 3.3 0.4 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.5 0.0 0.0 0.0 0.0 0.2 0.2 0.4 0.2 0.2 0.4 0.2 0.3 0.2 0.2 0.3 0.4 0.1 0.0 2.0 1.6 0.0 0.0 1.1 0.1 0.0 0.4 0.3 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 3.6 0.0 0.2 0.1 0.2 1.2 0.0 4.1 0.2 0.0 0.4 0.0 0.4 0.0 0.2 0.0 0.6 0.2 26.9 3.5 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 4.7 0.0 0.2 1.0 2.0 2.0 0.2 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.4 0.0 0.2 0.2 0.7 5.5 0.0 0.0 0.0 0.0 0.1 0.0 1.2 SAMD13 ENSG00000203943 "Sterile alpha motif domain containing 13" Q5VXD3 1 84298366-84389957 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.5;choroid plexus: 26.9;intestine: 22.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 20.3;Intestinal goblet cells: 18.0;Oligodendrocytes: 16.4;Paneth cells: 33.2;Spermatocytes: 22.5;Undifferentiated cells: 21.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 15 "basophil: 12.5" "Lineage enriched" "Detected in single" 15 "granulocytes: 12.5" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA058929 Enhanced Approved Mitochondria NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA058929: AB_2683855" "unprognostic (3.78e-2)" "unprognostic (4.93e-2)" "unprognostic (8.51e-3)" "unprognostic (7.55e-2)" "prognostic favorable (1.14e-8)" "unprognostic (1.78e-1)" "unprognostic (1.65e-6)" "unprognostic (2.05e-1)" "unprognostic (5.50e-2)" "unprognostic (2.80e-3)" "unprognostic (9.42e-2)" "unprognostic (3.29e-1)" "unprognostic (1.98e-7)" "unprognostic (3.99e-2)" "unprognostic (1.81e-1)" "unprognostic (1.17e-1)" "unprognostic (7.56e-3)" 0.9 3.4 22.3 1.5 30.7 2.8 2.4 11.3 25.7 1.6 26.9 19.5 3.4 1.7 4.1 0.8 4.1 1.8 2.4 19.6 29.0 1.4 0.4 0.9 1.2 29.0 29.4 0.3 1.8 1.2 1.0 0.8 27.7 4.0 22.0 0.8 17.6 2.1 6.2 1.2 3.8 2.5 29.9 1.1 6.1 13.1 35.5 2.8 9.8 3.0 0.6 1.8 0.4 32.5 0.5 2.3 1.1 3.5 3.6 3.3 2.3 0.3 0.2 0.3 0.2 0.0 3.4 3.6 6.3 0.1 0.7 0.4 0.4 1.2 0.5 2.0 1.7 1.3 1.7 0.3 0.8 4.4 0.0 1.3 1.6 0.1 1.0 2.5 8.2 7.8 0.5 1.1 1.0 1.1 5.1 0.5 3.5 2.9 2.3 0.5 2.5 1.5 6.5 2.1 1.4 5.1 0.1 0.1 8.1 1.4 1.0 4.1 1.4 1.4 0.3 0.3 1.0 2.4 0.5 6.3 0.3 3.8 1.1 12.5 0.3 0.0 0.0 0.5 0.2 0.2 0.0 0.0 0.7 0.7 0.3 0.4 0.1 0.5 0.3 0.8 0.0 0.3 22.3 30.7 11.3 25.7 19.6 29.0 29.0 29.4 27.7 29.9 35.5 32.5 1.7 0.0 0.6 2.0 0.3 0.4 0.7 0.7 0.6 1.2 3.8 2.9 1.0 2.8 1.1 1.8 0.0 4.5 0.1 20.3 5.9 2.1 5.6 5.4 1.6 1.6 11.4 6.1 5.2 0.6 0.6 1.4 3.6 4.7 5.7 2.0 3.3 0.1 1.5 0.0 5.8 18.0 0.0 2.4 1.6 5.8 1.8 1.4 8.8 6.5 0.4 2.7 0.0 7.1 16.4 1.1 33.2 2.6 0.1 2.0 3.8 2.9 1.1 0.1 0.0 1.8 0.7 22.5 5.5 2.2 0.3 0.8 0.7 4.1 21.3 1.2 SAMD15 "C14orf174, FAM15A, FLJ35963" ENSG00000100583 "Sterile alpha motif domain containing 15" Q9P1V8 14 77376689-77391497 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 15.3;testis: 17.7" "Group enriched" "Detected in many" 6 "Cone photoreceptor cells: 62.6;Early spermatids: 81.8;Endometrial ciliated cells: 38.8;Late spermatids: 111.7;Respiratory ciliated cells: 41.5;Rod photoreceptor cells: 75.7;Spermatocytes: 59.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "MCF7: 7.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA030673, HPA030677" Enhanced Approved "Nucleoplasm,Nuclear membrane,Nucleoli" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 77: Retina - Visual perception" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 9: Photoreceptor cells - Phototransduction" "Nucleoplasm, Nuclear membrane, Nucleoli" "HPA030673: AB_10600655, HPA030677: AB_10599938" "unprognostic (1.09e-1)" "unprognostic (1.65e-1)" "unprognostic (3.76e-2)" "unprognostic (1.15e-1)" "unprognostic (1.02e-2)" "unprognostic (1.38e-2)" "unprognostic (3.70e-3)" "unprognostic (5.20e-2)" "unprognostic (5.76e-2)" "unprognostic (1.11e-1)" "unprognostic (3.83e-3)" "unprognostic (6.19e-2)" "unprognostic (2.53e-3)" "unprognostic (6.87e-3)" "unprognostic (9.90e-2)" "unprognostic (3.73e-3)" "unprognostic (1.76e-2)" 0.5 0.8 1.7 0.3 2.8 0.6 1.0 0.7 1.5 0.7 7.7 0.2 0.3 1.0 5.3 0.2 4.5 1.1 0.1 1.7 3.4 1.9 0.1 0.8 1.4 2.8 3.5 0.7 2.0 2.4 2.4 0.3 2.0 0.7 0.3 15.3 0.3 0.7 0.2 0.5 0.2 0.3 1.4 0.2 0.4 17.7 2.7 0.4 3.9 0.0 1.4 0.8 0.2 0.8 2.5 3.4 1.3 2.7 0.3 1.4 1.2 1.0 0.9 2.6 2.3 2.5 2.2 2.8 1.1 1.0 2.3 2.4 0.9 1.4 3.7 0.2 0.5 0.4 1.0 0.6 0.1 0.5 2.9 1.3 0.9 2.3 0.2 1.1 1.8 1.4 0.3 0.7 1.1 7.6 0.6 0.2 0.5 0.6 1.0 1.2 1.2 0.1 4.6 1.4 2.8 1.8 3.5 0.5 0.5 0.5 4.3 0.8 0.7 2.5 1.4 2.6 1.3 0.4 2.4 1.8 3.1 0.1 1.3 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.7 2.8 0.7 1.5 1.7 3.4 2.8 3.5 2.0 1.4 2.7 0.8 0.7 0.0 0.0 1.0 0.3 0.3 0.5 0.6 0.0 11.2 0.9 0.9 1.9 2.8 1.8 0.0 62.6 0.3 0.8 0.7 1.9 2.8 81.8 38.8 4.6 0.5 3.6 0.0 1.3 0.6 0.2 1.0 0.0 1.4 0.0 1.3 0.4 0.0 0.1 3.3 0.6 0.5 0.0 0.0 0.0 111.7 1.5 0.3 0.0 0.0 0.1 5.5 0.0 0.5 0.4 0.9 0.1 0.0 0.0 0.2 0.0 3.5 41.5 75.7 0.0 1.0 1.0 59.3 7.3 0.0 0.0 0.3 0.3 6.0 0.1 0.3 SAMD4A "DKFZP434H0350, hSmaug1, KIAA1053, SAMD4, Smaug, SMG, SMGA" ENSG00000020577 "Sterile alpha motif domain containing 4A" Q9UPU9 14 54566117-54793315 "Predicted intracellular proteins" "Translation regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 94.3;testis: 107.9" "Group enriched" "Detected in many" 4 "Early spermatids: 1176.0;Late spermatids: 2275.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.2;non-classical monocyte: 1.0" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043061, HPA065309" Approved Approved "Cell Junctions,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 34: Spermatids - Unknown function" "Cell Junctions" Cytosol "HPA043061: AB_2678299, HPA065309: AB_2685462" "unprognostic (1.46e-1)" "unprognostic (8.10e-3)" "unprognostic (9.66e-3)" "unprognostic (1.18e-4)" "unprognostic (2.79e-1)" "unprognostic (6.37e-2)" "unprognostic (1.46e-1)" "unprognostic (1.17e-1)" "unprognostic (1.13e-1)" "unprognostic (1.75e-1)" "unprognostic (1.98e-1)" "unprognostic (7.74e-2)" "unprognostic (1.09e-2)" "unprognostic (2.83e-2)" "unprognostic (8.27e-2)" "unprognostic (5.41e-2)" "unprognostic (1.51e-1)" 16.6 4.2 27.4 8.9 33.1 0.4 13.1 42.3 24.9 13.0 14.1 37.6 3.2 26.1 4.0 6.7 12.0 6.0 47.8 22.6 40.3 12.4 16.6 21.2 4.6 79.0 46.2 4.5 6.2 3.8 6.1 9.2 69.4 14.5 4.8 2.6 7.0 9.4 94.3 8.9 10.4 17.1 64.1 7.1 10.9 107.9 41.8 1.1 7.0 39.3 3.1 17.7 12.8 60.8 32.9 2.9 6.7 3.4 14.0 21.3 11.7 27.4 41.4 22.3 22.0 36.8 7.8 1.8 14.0 41.7 8.8 22.6 6.6 14.2 32.8 16.5 2.8 0.0 4.0 7.7 7.7 0.0 0.2 12.6 5.3 15.9 23.4 6.5 17.1 0.0 2.6 0.0 11.0 2.4 0.4 0.1 3.1 0.2 7.5 0.9 13.5 0.1 11.0 10.8 1.0 10.7 4.0 5.2 15.9 13.8 21.0 0.3 37.1 26.6 41.1 6.6 8.7 0.1 0.1 0.0 7.5 0.6 8.4 0.0 0.6 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.2 27.4 33.1 42.3 24.9 22.6 40.3 79.0 46.2 69.4 64.1 41.8 60.8 16.0 25.6 1.5 170.1 7.4 39.6 47.0 12.0 1.2 2.4 6.2 6.1 278.5 14.3 9.9 18.4 8.4 10.5 1.6 4.4 3.9 9.9 1176.0 13.7 45.3 30.9 6.0 5.7 64.6 8.0 1.8 47.3 1.5 29.3 22.8 0.8 10.8 62.6 11.6 10.1 173.7 1.5 6.1 15.3 28.9 2275.7 14.6 13.0 24.9 72.1 12.8 1.5 1.0 380.5 140.7 19.8 5.5 23.7 0.3 55.1 5.6 22.9 4.0 5.4 13.1 79.7 37.1 17.1 7.6 0.4 24.3 1.9 5.7 0.3 1.7 44.5 SAP30 ENSG00000164105 "Sin3A associated protein 30" O75446 4 173369969-173377532 "Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Kupffer cells: 77.2;Macrophages: 77.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Karpas-707: 181.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022627, HPA059012" Enhanced Supported Nucleoplasm "Intracellular and membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm "CAB022627: , HPA059012: AB_2683880" "unprognostic (1.53e-1)" "unprognostic (3.67e-2)" "unprognostic (3.26e-1)" "unprognostic (1.39e-1)" "unprognostic (5.83e-2)" "unprognostic (8.71e-2)" "prognostic unfavorable (1.24e-6)" "unprognostic (4.95e-2)" "unprognostic (7.23e-2)" "unprognostic (3.93e-2)" "unprognostic (4.48e-1)" "unprognostic (1.93e-2)" "prognostic unfavorable (1.54e-7)" "unprognostic (3.97e-1)" "unprognostic (5.70e-2)" "unprognostic (1.30e-1)" "unprognostic (2.21e-1)" 17.4 12.9 17.4 13.3 19.7 23.4 12.8 18.4 21.6 13.9 16.1 25.6 9.5 13.2 9.6 9.9 16.9 8.6 20.4 17.0 18.2 6.2 9.0 12.8 8.0 19.3 18.2 14.6 7.3 4.5 8.1 7.1 19.2 11.4 7.0 16.3 11.6 9.7 10.5 8.5 12.5 12.4 18.7 15.7 18.4 24.7 17.6 10.3 10.6 7.4 6.6 19.5 12.6 25.3 49.0 16.3 46.3 45.2 29.0 17.9 10.1 22.5 19.3 24.7 30.4 7.0 19.4 43.9 10.3 26.3 31.1 12.0 37.8 19.1 18.9 49.6 35.9 58.7 39.6 20.0 27.5 34.0 35.9 29.8 9.2 21.1 21.2 34.7 29.3 31.5 30.8 181.4 32.2 20.9 48.4 38.0 20.5 21.7 31.3 38.9 16.5 31.6 15.1 7.8 37.5 79.1 31.8 31.9 14.9 11.8 13.5 20.0 29.1 17.6 23.9 41.4 52.8 101.5 39.1 41.8 56.8 81.6 51.2 0.4 1.3 0.0 0.6 0.7 0.2 0.1 0.3 0.4 1.0 0.2 0.0 0.2 0.5 0.0 0.4 0.0 0.4 0.2 17.4 19.7 18.4 21.6 17.0 18.2 19.3 18.2 19.2 18.7 17.6 25.3 42.1 0.0 2.3 11.1 7.2 51.7 6.6 3.9 16.5 26.2 25.5 29.3 28.9 4.3 3.7 7.3 22.9 2.1 22.5 4.8 0.0 2.2 23.1 23.6 34.3 27.3 19.7 20.2 12.5 3.5 9.3 19.9 19.4 7.4 7.0 13.5 14.6 9.0 9.3 25.2 14.6 10.5 0.0 77.2 13.8 6.2 10.2 77.0 33.8 3.7 15.2 57.7 2.1 7.1 15.4 2.4 2.7 6.4 17.6 8.6 6.4 6.2 9.9 46.3 52.6 12.5 31.7 63.7 15.2 16.1 53.0 1.2 27.0 12.3 11.1 4.1 SAR1B SARA2 ENSG00000152700 "Secretion associated Ras related GTPase 1B" Q9Y6B6 5 134601149-134649271 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 413.3;Hepatocytes: 267.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006923, HPA048368" Supported Approved "Endoplasmic reticulum" NA NA 430000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 16: U-266 - Nucleosome" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Endoplasmic reticulum" "HPA006923: AB_1856577, HPA048368: AB_2680373" "unprognostic (6.14e-2)" "unprognostic (7.33e-2)" "unprognostic (5.32e-2)" "prognostic favorable (7.11e-4)" "unprognostic (1.23e-1)" "unprognostic (5.92e-2)" "prognostic favorable (6.59e-4)" "unprognostic (1.88e-2)" "unprognostic (1.69e-1)" "unprognostic (2.69e-1)" "unprognostic (7.32e-2)" "unprognostic (6.87e-2)" "unprognostic (2.45e-1)" "unprognostic (5.69e-2)" "unprognostic (4.66e-2)" "unprognostic (7.50e-3)" "unprognostic (1.87e-2)" 30.9 46.4 27.5 24.2 40.6 26.0 35.8 40.8 41.7 27.3 40.6 40.9 68.5 14.9 34.9 36.0 17.7 28.2 46.8 31.0 37.5 57.1 163.9 19.7 24.4 43.9 40.5 13.5 32.8 64.9 24.7 20.7 44.7 38.7 36.5 20.3 36.3 29.7 147.5 16.8 69.7 26.7 40.3 20.0 43.4 66.0 35.9 22.7 29.7 140.6 33.6 36.2 20.3 53.9 57.8 49.6 36.0 81.3 111.6 53.4 48.3 95.4 80.0 84.1 127.9 84.3 79.7 31.9 78.3 98.6 116.6 52.1 62.8 92.5 108.0 73.6 37.0 33.6 78.0 81.5 91.7 29.1 44.7 60.4 57.8 97.7 82.7 42.3 64.1 40.9 44.3 71.9 87.0 85.3 38.6 43.6 12.7 70.7 34.4 33.7 62.7 70.2 61.7 91.2 36.8 16.0 67.2 36.1 71.4 47.2 74.2 35.5 51.7 72.8 44.0 66.7 72.3 90.0 215.4 58.7 56.2 55.7 81.6 22.2 70.5 55.0 42.3 71.2 52.9 52.7 48.2 49.7 64.0 34.7 42.9 41.6 25.5 35.8 80.5 43.6 77.1 71.3 27.5 40.6 40.8 41.7 31.0 37.5 43.9 40.5 44.7 40.3 35.9 53.9 49.3 32.1 36.9 21.5 45.6 37.6 44.0 112.9 22.2 30.4 56.0 35.7 86.7 61.5 102.6 57.0 41.7 33.1 44.5 77.0 56.7 47.6 413.3 43.0 51.3 35.3 27.6 44.2 31.6 83.9 43.5 46.1 68.3 45.8 26.6 28.3 38.9 267.7 52.8 33.7 32.8 55.2 89.5 52.9 56.6 76.9 36.7 47.1 64.0 20.6 38.3 41.8 20.6 29.7 66.5 60.4 36.2 44.8 165.8 75.1 210.7 121.4 99.8 40.3 19.7 41.2 47.7 106.8 47.3 51.1 51.1 115.2 47.0 43.0 46.3 96.5 SASS6 "DKFZp761A078, FLJ22097, SAS-6, SAS6" ENSG00000156876 "SAS-6 centriolar assembly protein" Q6UVJ0 1 100083563-100132955 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Spermatocytes: 77.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "basophil: 3.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028187 Uncertain NA NA "Cluster 34: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "HPA028187: AB_10602220" "unprognostic (1.57e-1)" "unprognostic (2.52e-1)" "unprognostic (3.07e-2)" "unprognostic (2.06e-2)" "unprognostic (1.31e-1)" "unprognostic (3.02e-3)" "unprognostic (1.21e-4)" "unprognostic (1.27e-1)" "unprognostic (8.43e-3)" "unprognostic (4.73e-2)" "unprognostic (6.56e-2)" "unprognostic (3.71e-2)" "unprognostic (7.76e-8)" "unprognostic (1.19e-2)" "unprognostic (2.25e-1)" "unprognostic (1.20e-1)" "unprognostic (2.54e-1)" 1.3 1.2 1.0 2.9 1.2 6.0 2.8 1.6 1.5 1.6 0.8 2.2 2.8 2.0 2.2 2.1 1.4 1.0 1.0 0.8 1.0 1.0 1.4 1.3 4.2 1.1 1.2 1.8 1.4 3.9 1.6 2.0 1.1 2.1 3.0 5.7 1.8 1.5 1.3 2.1 2.2 1.8 1.1 2.1 2.1 6.7 1.0 4.3 1.5 0.9 3.6 1.4 1.6 1.3 17.0 5.2 13.1 11.5 1.5 2.6 19.3 10.7 4.7 13.5 15.6 9.0 8.5 18.5 8.0 3.7 8.0 14.8 18.0 6.5 18.6 8.9 17.8 16.2 10.9 11.3 0.9 26.8 14.5 1.3 2.8 11.4 9.0 2.7 7.3 12.2 25.8 17.6 6.7 4.8 22.2 12.9 17.5 11.1 10.7 16.1 25.9 9.4 6.5 8.1 9.5 14.0 9.9 17.0 8.7 9.4 8.6 15.9 3.8 9.5 11.6 10.9 14.9 7.4 18.5 24.6 7.7 17.7 5.3 3.9 0.1 1.0 0.7 0.6 0.9 1.6 0.8 0.7 0.5 0.7 0.7 0.6 0.7 0.6 0.5 0.2 0.9 0.3 1.0 1.2 1.6 1.5 0.8 1.0 1.1 1.2 1.1 1.1 1.0 1.3 7.2 0.0 2.3 8.5 12.8 4.0 2.8 7.1 6.8 19.4 8.4 9.4 2.9 7.2 5.9 1.8 16.7 13.6 13.5 2.4 1.9 7.5 15.7 7.4 5.8 5.8 4.2 33.2 7.6 5.6 17.3 7.0 7.1 5.4 5.7 15.0 6.8 3.1 9.1 8.4 9.6 4.8 14.2 8.4 4.7 6.2 8.1 5.8 1.8 5.6 6.1 13.3 20.6 5.0 16.1 6.2 2.7 10.9 19.7 4.5 2.2 4.3 4.9 23.0 0.0 12.6 5.9 77.4 36.0 11.9 4.1 5.1 7.9 4.0 8.8 2.1 SAV1 "salvador, WW45, WWP4" ENSG00000151748 "Salvador family WW domain containing protein 1" Q9H4B6 14 50632058-50668306 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001808 Approved Supported Cytosol NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 50: Fibroblasts - ECM organization" Cytosol "HPA001808: AB_2666441" "prognostic favorable (2.92e-5)" "unprognostic (5.17e-2)" "unprognostic (1.24e-1)" "unprognostic (1.52e-2)" "unprognostic (4.38e-1)" "unprognostic (1.42e-1)" "unprognostic (1.44e-3)" "unprognostic (3.00e-2)" "unprognostic (1.82e-1)" "unprognostic (1.37e-1)" "unprognostic (1.41e-3)" "unprognostic (5.20e-2)" "prognostic favorable (3.83e-6)" "unprognostic (2.32e-1)" "unprognostic (2.05e-1)" "unprognostic (1.28e-2)" "unprognostic (1.90e-3)" 32.2 16.4 14.0 12.8 16.7 7.3 35.3 15.1 16.9 24.5 22.0 17.0 15.3 23.3 18.8 15.8 21.2 26.2 24.2 12.8 15.0 22.9 17.6 20.2 15.7 16.5 15.1 37.7 34.4 27.0 8.5 17.0 16.1 27.6 12.6 17.6 45.5 19.2 23.1 17.8 13.2 17.7 14.7 18.6 18.9 30.6 16.6 10.3 34.2 27.1 14.7 16.7 18.7 19.6 96.3 10.7 17.8 12.4 43.5 39.8 22.4 26.6 87.3 34.1 43.4 16.0 47.8 14.9 63.9 26.4 17.8 42.8 25.7 28.9 62.9 45.6 20.8 16.4 16.4 11.4 21.3 17.9 14.0 24.9 36.5 15.3 33.8 25.8 24.5 15.9 27.5 7.2 42.5 17.9 15.1 11.0 33.1 21.6 17.3 17.2 49.5 6.1 21.5 13.6 22.2 16.8 47.1 27.7 41.3 28.9 20.3 18.0 17.7 16.2 55.5 22.4 16.4 11.3 15.4 9.0 11.1 7.2 22.1 0.6 0.3 0.0 0.9 0.3 0.9 3.3 0.7 0.5 0.3 3.4 0.5 0.7 0.5 0.5 0.4 1.2 1.0 0.4 14.0 16.7 15.1 16.9 12.8 15.0 16.5 15.1 16.1 14.7 16.6 19.6 76.4 35.3 44.0 9.4 35.8 65.9 37.2 19.1 24.5 19.6 76.4 60.6 39.1 15.7 35.1 18.4 25.0 19.9 14.7 11.2 17.6 40.5 92.5 39.6 47.3 76.9 5.4 27.0 10.4 47.6 23.0 59.3 11.7 58.1 2.5 46.4 59.3 14.5 10.5 5.0 10.0 10.1 10.2 13.5 61.5 26.1 66.8 34.1 30.2 12.2 11.6 26.9 2.1 12.5 27.0 66.5 14.6 42.5 7.4 81.4 12.1 16.3 33.3 26.4 6.6 41.8 45.1 41.4 38.8 14.6 59.5 23.1 9.4 17.7 9.6 34.1 SAYSD1 "C6orf64, FLJ11101" ENSG00000112167 "SAYSVFN motif domain containing 1" Q9NPB0 6 39104063-39115186 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 55.5" "Group enriched" "Detected in many" 4 "Early spermatids: 136.1;Late spermatids: 63.2;Spermatocytes: 223.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007959 Approved Supported Vesicles NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 23: Testis - Cell cycle regulation" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "HPA007959: AB_1078359" "unprognostic (2.65e-1)" "unprognostic (1.49e-2)" "unprognostic (2.03e-2)" "unprognostic (2.58e-1)" "unprognostic (3.70e-1)" "unprognostic (2.56e-1)" "unprognostic (9.90e-3)" "unprognostic (1.96e-2)" "unprognostic (6.50e-2)" "unprognostic (1.82e-3)" "unprognostic (5.08e-2)" "unprognostic (9.90e-2)" "unprognostic (2.54e-2)" "unprognostic (1.79e-1)" "unprognostic (9.78e-3)" "unprognostic (2.27e-1)" "unprognostic (2.00e-3)" 8.8 7.9 7.8 6.5 8.4 7.6 10.5 8.3 10.3 8.6 8.0 8.7 9.9 8.4 11.1 7.5 8.6 6.9 8.3 8.2 8.3 9.6 10.1 7.0 10.3 8.0 8.1 8.8 11.1 7.7 6.3 6.7 8.1 9.2 7.8 6.8 12.6 8.2 7.0 7.4 9.4 6.8 8.1 7.5 7.8 55.5 8.1 17.0 8.7 7.0 9.4 7.2 6.9 9.6 14.8 9.4 8.3 9.9 13.4 17.7 8.6 6.7 7.3 7.9 8.3 13.6 10.2 13.4 9.4 8.8 11.2 9.9 7.3 6.3 8.3 8.5 13.2 8.8 5.5 11.9 10.9 10.1 12.7 12.3 15.4 3.1 7.8 5.6 7.4 19.9 15.1 7.9 9.0 20.4 16.1 16.6 7.2 9.7 4.8 2.3 10.1 5.4 16.7 10.3 23.3 9.4 11.6 10.0 10.9 6.6 16.4 13.1 9.7 10.4 7.5 3.2 8.8 0.2 4.3 16.2 6.0 14.4 7.8 10.6 10.8 24.9 14.0 15.1 16.0 16.4 15.2 12.8 11.4 18.5 21.0 17.9 5.2 15.8 15.8 9.0 22.2 12.1 7.8 8.4 8.3 10.3 8.2 8.3 8.0 8.1 8.1 8.1 8.1 9.6 19.3 3.2 6.0 4.6 11.4 15.4 13.2 29.1 8.6 6.4 26.4 21.8 18.8 21.5 17.0 18.4 8.4 33.1 8.3 10.5 17.6 22.9 136.1 22.8 14.0 11.2 8.4 13.5 3.2 21.8 32.7 16.8 4.6 19.0 8.2 13.8 6.4 23.3 26.8 6.7 4.2 16.5 2.0 13.9 15.7 63.2 20.5 13.2 12.4 0.0 11.9 15.5 12.3 9.0 6.3 15.9 9.7 19.2 5.3 22.6 21.8 28.3 19.2 4.1 6.6 13.1 17.3 223.6 14.5 11.6 16.6 12.3 12.8 10.2 20.1 14.9 SCAP KIAA0199 ENSG00000114650 "SREBF chaperone" Q12770 3 47413681-47477126 "Predicted membrane proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 135.2" "Cell type enhanced" "Detected in many" "Theca cells: 100.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004713 Approved NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" "HPA004713: AB_1079868" "unprognostic (4.02e-2)" "unprognostic (2.56e-1)" "unprognostic (1.91e-1)" "unprognostic (4.74e-2)" "unprognostic (1.51e-1)" "unprognostic (1.26e-1)" "unprognostic (8.74e-2)" "unprognostic (3.85e-2)" "unprognostic (1.28e-2)" "unprognostic (7.10e-2)" "prognostic favorable (7.14e-4)" "unprognostic (4.07e-2)" "prognostic favorable (4.33e-5)" "unprognostic (3.15e-2)" "unprognostic (1.39e-1)" "unprognostic (1.34e-1)" "unprognostic (7.06e-3)" 23.4 135.2 30.2 15.8 27.7 17.1 25.8 35.3 37.5 29.0 35.2 36.8 24.5 31.4 17.4 37.5 28.2 14.5 29.8 27.8 26.2 33.3 73.7 22.2 15.9 32.1 27.5 35.4 34.1 28.3 34.0 18.2 30.1 29.1 21.8 27.5 25.1 18.6 27.5 47.0 34.3 20.5 18.8 37.1 32.3 39.2 34.0 18.6 30.6 19.3 15.6 31.7 29.3 26.0 19.7 28.2 28.8 45.6 51.6 26.4 51.3 18.8 27.9 30.0 28.3 38.0 31.9 31.5 26.7 30.4 30.7 20.3 41.1 38.8 31.7 23.6 29.0 54.1 37.7 40.9 51.4 33.4 32.5 33.2 40.1 36.4 42.2 24.9 26.1 32.0 38.5 21.4 24.8 28.9 37.1 49.2 30.7 39.7 40.1 20.1 25.9 37.5 24.4 37.1 19.0 35.1 27.1 33.8 18.8 36.8 29.5 37.6 22.0 27.2 33.1 39.7 26.8 21.2 24.6 18.3 27.6 30.2 20.9 6.0 5.9 6.5 6.6 4.9 8.7 5.5 5.4 6.0 7.0 5.3 6.1 6.1 15.8 6.7 4.2 5.4 7.3 5.0 30.2 27.7 35.3 37.5 27.8 26.2 32.1 27.5 30.1 18.8 34.0 26.0 15.0 0.0 16.0 34.0 11.6 11.6 9.8 14.5 19.9 23.2 20.2 18.9 14.6 11.5 16.2 20.2 29.2 27.6 9.8 55.3 0.0 13.9 13.0 11.5 12.8 12.9 12.0 10.1 39.3 15.1 15.8 16.9 26.5 16.3 7.0 53.5 7.9 46.0 16.3 53.8 39.7 20.7 10.2 13.4 8.3 28.6 19.6 10.4 24.9 15.0 7.7 18.6 14.4 27.6 30.2 10.6 33.8 21.4 18.5 10.2 40.6 9.7 17.9 34.7 32.9 14.0 22.3 14.6 25.0 19.6 11.6 79.1 12.1 100.1 31.4 9.0 SCCPDH "CGI-49, NET11" ENSG00000143653 "Saccharopine dehydrogenase (putative)" Q8NBX0 1 246724409-246768137 "Metabolic proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 159.5" "Group enriched" "Detected in all" 4 "Early spermatids: 1380.7;Spermatocytes: 822.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 20 "basophil: 872.9" "Lineage enriched" "Detected in all" 26 "granulocytes: 872.9" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050775, HPA076030" Enhanced Approved Vesicles NA NA "Cluster 38: Basophils - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "HPA050775: AB_2681231, HPA076030: " "unprognostic (4.25e-1)" "unprognostic (3.11e-1)" "unprognostic (1.22e-1)" "unprognostic (1.75e-2)" "unprognostic (2.83e-2)" "unprognostic (6.43e-2)" "unprognostic (1.25e-1)" "unprognostic (1.10e-1)" "unprognostic (1.60e-1)" "unprognostic (5.51e-2)" "unprognostic (1.93e-1)" "unprognostic (3.60e-1)" "unprognostic (2.70e-2)" "unprognostic (9.63e-2)" "unprognostic (1.13e-1)" "unprognostic (2.24e-1)" "unprognostic (3.93e-2)" 26.6 53.7 35.1 14.4 45.5 35.7 23.6 51.5 43.2 22.6 40.8 27.2 34.4 26.2 17.6 9.3 31.6 21.6 32.8 35.3 45.4 49.8 158.2 21.0 13.5 64.0 45.2 22.4 18.8 36.5 24.3 23.8 64.3 39.4 26.8 31.7 15.3 26.0 60.7 24.1 34.6 24.0 57.0 11.5 28.0 159.5 47.3 20.1 33.5 54.7 10.6 81.5 12.0 86.8 55.3 53.2 37.7 22.8 44.5 55.7 0.5 42.3 58.8 70.1 58.3 32.7 150.6 29.3 53.8 49.0 38.9 17.7 32.4 12.6 71.6 40.8 11.9 49.6 46.9 65.9 41.6 97.1 40.7 37.6 5.9 47.4 4.8 65.7 76.4 60.0 62.9 0.1 70.9 13.5 101.6 122.6 56.5 29.6 41.7 83.8 48.5 0.3 216.6 128.2 42.7 48.0 57.3 2.5 39.0 20.2 42.1 99.6 49.8 32.1 28.5 78.7 110.5 138.0 51.1 17.4 54.7 130.2 43.3 872.9 24.3 44.1 18.1 22.2 22.4 11.2 5.4 15.7 10.7 9.4 7.1 22.0 6.4 34.1 15.4 18.2 4.0 17.1 35.1 45.5 51.5 43.2 35.3 45.4 64.0 45.2 64.3 57.0 47.3 86.8 25.0 6.4 11.5 25.8 8.0 30.1 40.6 54.6 1.8 31.2 42.4 17.5 38.0 55.8 40.5 152.6 18.8 41.4 14.6 42.4 31.3 67.2 1380.7 72.7 39.4 23.6 44.9 54.7 23.7 69.0 17.4 35.7 32.6 111.9 57.2 49.2 22.5 187.8 89.4 6.7 20.5 27.4 52.9 45.7 13.7 245.6 47.5 29.7 48.0 10.3 20.3 67.4 18.6 27.2 37.3 75.2 27.8 47.4 8.3 49.2 138.4 69.7 79.4 39.2 19.7 36.7 39.4 822.3 76.2 5.6 68.5 84.6 17.0 42.8 55.0 201.9 SCD "FADS5, SCDOS" ENSG00000099194 "Stearoyl-CoA desaturase" O00767 10 100347233-100364826 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 1233.7;brain: 839.9;liver: 583.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 389.6;Granulosa cells: 187.3;Hepatocytes: 840.3;Oligodendrocytes: 451.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "ASC diff: 2534.2;CAPAN-2: 1824.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA012107, HPA063921" Approved Enhanced "Endoplasmic reticulum" No Yes "Cluster 7: Monocytes - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum" "HPA012107: AB_1856610, HPA063921: AB_2685154" "unprognostic (2.10e-1)" "unprognostic (2.62e-3)" "unprognostic (7.86e-2)" "unprognostic (5.19e-2)" "unprognostic (1.24e-1)" "unprognostic (6.16e-2)" "unprognostic (1.13e-1)" "unprognostic (3.88e-2)" "unprognostic (6.53e-2)" "unprognostic (2.72e-1)" "unprognostic (1.47e-1)" "unprognostic (1.69e-1)" "prognostic unfavorable (7.56e-5)" "unprognostic (7.18e-2)" "unprognostic (3.27e-1)" "unprognostic (4.73e-2)" "prognostic unfavorable (7.79e-5)" 1233.7 131.2 408.7 25.7 525.8 23.0 261.5 535.7 522.1 43.2 156.6 42.9 93.1 15.4 25.5 107.8 5.0 28.7 47.1 349.1 457.5 18.5 583.8 142.8 17.2 775.0 508.9 49.6 22.6 79.5 10.3 19.9 637.8 100.1 39.7 17.9 112.6 11.2 6.1 27.0 36.0 15.9 574.4 15.3 25.2 51.8 538.7 18.4 13.0 7.2 21.0 22.5 41.9 839.9 411.2 373.3 777.6 536.4 2534.2 1449.4 158.2 43.4 948.3 101.6 536.6 323.8 1824.4 173.3 33.7 102.2 461.8 716.4 433.7 1549.5 88.9 59.4 179.6 97.5 219.3 653.4 488.4 136.9 100.9 795.5 459.4 395.0 688.9 273.1 196.2 375.3 275.4 513.3 41.7 646.8 155.9 163.3 270.7 120.7 106.3 72.6 287.4 550.4 443.8 455.3 48.9 185.3 85.8 399.7 834.9 224.2 447.7 291.3 79.0 10.0 115.9 9.1 89.8 141.4 81.5 262.9 184.4 416.0 65.9 0.0 0.8 0.0 1.4 1.6 2.3 0.6 0.5 0.7 2.7 0.9 0.4 1.3 0.1 1.4 0.0 1.5 0.0 1.2 408.7 525.8 535.7 522.1 349.1 457.5 775.0 508.9 637.8 574.4 538.7 839.9 3.8 54.5 389.6 34.0 15.7 3.7 4.5 121.8 0.6 6.5 16.1 6.2 11.2 28.6 66.2 0.0 6.2 3.0 4.7 21.5 0.0 14.6 52.6 13.9 9.0 12.5 25.8 15.8 4.8 67.9 71.7 15.9 25.0 26.9 6.3 187.3 32.9 840.3 34.1 26.9 5.2 16.4 52.9 113.5 4.2 93.0 3.7 21.2 58.7 8.4 10.2 11.9 2.1 18.6 451.5 29.6 2.7 1.5 3.7 31.4 16.2 4.9 31.0 6.2 0.0 3.6 25.7 2.0 1.2 26.7 2.3 17.4 6.6 97.8 38.9 8.2 SCLY SCL ENSG00000132330 "Selenocysteine lyase" Q96I15 2 238060924-238099413 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lyase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 39.1" "Group enriched" "Detected in many" 13 "Early spermatids: 90.6;Late spermatids: 156.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020190, HPA055760" Uncertain Enhanced "Golgi apparatus" NA NA 300000 "Cluster 26: Non-specific - Mitochondria" "Cluster 29: Non-specific - Vesicular transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" "Golgi apparatus" "HPA020190: , HPA055760: AB_2682910" "unprognostic (7.39e-3)" "unprognostic (1.43e-1)" "unprognostic (3.29e-2)" "unprognostic (8.65e-5)" "unprognostic (8.96e-2)" "unprognostic (9.85e-3)" "unprognostic (1.14e-3)" "unprognostic (4.24e-2)" "unprognostic (1.59e-2)" "unprognostic (8.38e-2)" "unprognostic (3.98e-3)" "unprognostic (1.03e-2)" "unprognostic (1.02e-3)" "unprognostic (3.73e-1)" "unprognostic (4.37e-2)" "unprognostic (2.50e-3)" "unprognostic (1.98e-1)" 5.1 4.3 7.2 5.3 9.4 5.0 4.9 9.4 9.3 6.8 6.4 7.3 8.5 8.1 5.6 5.9 6.3 3.8 8.1 6.8 8.2 12.9 39.1 4.7 5.7 9.2 8.8 6.3 22.8 6.1 5.0 2.0 9.4 5.9 3.2 4.6 4.4 4.1 6.4 3.5 8.6 3.9 7.3 7.2 5.8 16.8 8.3 5.9 7.2 3.5 4.3 7.8 5.1 10.4 11.1 19.1 11.9 31.1 9.0 6.4 23.2 11.2 5.6 11.3 14.3 11.6 8.0 18.9 3.3 5.9 35.4 16.4 44.1 21.5 10.9 21.2 41.8 21.1 24.0 37.6 16.7 17.6 18.2 7.1 11.6 21.3 22.0 5.1 21.0 26.1 38.0 5.1 11.7 16.9 17.9 33.0 36.4 16.0 15.6 22.0 23.3 18.2 11.3 3.6 13.1 28.9 12.0 19.4 20.6 8.2 6.3 26.5 8.5 16.3 11.8 24.2 23.7 14.2 13.3 9.3 11.3 37.0 14.4 1.1 3.2 4.0 2.6 2.3 2.0 2.6 3.1 4.4 3.3 1.6 2.3 2.6 0.5 2.9 3.5 0.6 3.2 2.8 7.2 9.4 9.4 9.3 6.8 8.2 9.2 8.8 9.4 7.3 8.3 10.4 2.2 0.0 0.0 0.0 4.6 1.7 2.4 1.9 5.7 5.4 1.7 1.9 2.6 1.5 1.2 0.0 8.4 1.4 3.4 1.9 3.9 5.3 90.6 1.7 3.4 2.4 2.4 9.4 0.0 3.7 2.1 1.9 5.1 2.6 0.0 3.5 1.8 3.3 4.0 6.7 0.0 3.3 8.2 0.9 3.2 156.3 3.1 2.1 1.8 0.0 2.7 2.6 2.1 0.0 0.0 3.0 5.0 0.0 4.9 1.9 3.9 2.7 1.9 6.9 0.0 1.9 3.2 6.2 5.6 3.4 1.6 0.7 4.4 2.2 4.8 1.8 SCML4 dJ47M23.1 ENSG00000146285 "Scm polycomb group protein like 4" Q8N228 6 107702154-107824317 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 10.1;lymphoid tissue: 12.1" "Cell type enhanced" "Detected in many" "dendritic cells: 31.7;Early spermatids: 72.1;Late spermatids: 168.4;NK-cells: 35.0;T-cells: 73.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 6 "gdT-cell: 48.2;MAIT T-cell: 47.7;memory CD4 T-cell: 74.8;memory CD8 T-cell: 65.7;naive CD4 T-cell: 69.1;naive CD8 T-cell: 59.5;NK-cell: 53.2" "Group enriched" "Detected in many" 6 "NK-cells: 53.2;T-cells: 74.8" "Cell line enriched" "Detected in some" 5 "HDLM-2: 65.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA063326, HPA065958" Approved Approved Nucleoplasm NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 58: T-cells - T-cell receptor" Nucleoplasm "HPA063326: AB_2684986, HPA065958: AB_2685587" "unprognostic (4.00e-5)" "unprognostic (2.10e-3)" "unprognostic (4.71e-2)" "unprognostic (4.24e-3)" "unprognostic (1.38e-3)" "unprognostic (4.75e-4)" "unprognostic (3.84e-3)" "unprognostic (6.65e-3)" "unprognostic (4.26e-1)" "unprognostic (1.53e-2)" "unprognostic (2.13e-4)" "unprognostic (3.68e-1)" "unprognostic (3.77e-4)" "unprognostic (8.65e-2)" "unprognostic (3.68e-2)" "unprognostic (2.52e-3)" "unprognostic (5.09e-3)" 0.6 0.8 0.8 7.2 0.6 3.3 1.0 1.2 0.7 0.5 0.2 2.3 10.1 0.5 4.6 0.9 0.7 1.4 0.6 0.6 0.9 0.6 1.6 1.7 12.1 0.5 0.5 0.6 0.7 0.2 1.9 0.3 0.3 0.6 2.0 0.9 1.0 0.4 0.4 0.9 8.2 0.5 0.1 7.4 2.8 2.2 1.3 9.3 0.8 0.2 9.8 1.1 0.7 0.6 0.1 0.1 0.1 0.1 0.1 0.3 0.8 0.1 0.0 0.0 0.0 1.4 0.2 0.2 0.1 0.0 0.1 0.2 0.0 0.0 0.1 65.1 0.0 0.1 0.4 0.2 0.0 0.3 0.1 0.1 0.0 0.0 0.1 0.2 0.2 0.7 0.1 0.1 0.0 0.1 0.0 0.2 0.1 0.1 0.0 0.1 0.3 0.1 0.0 0.2 0.1 0.3 0.1 0.1 13.8 0.2 0.1 0.1 0.0 0.1 0.2 0.3 0.1 0.3 0.2 0.7 0.1 0.1 0.1 4.2 0.3 3.5 48.2 0.1 47.7 10.1 74.8 65.7 0.2 5.8 69.1 59.5 6.6 53.2 0.4 1.2 5.8 26.6 0.8 0.6 1.2 0.7 0.6 0.9 0.5 0.5 0.3 0.1 1.3 0.6 0.5 0.0 0.0 0.7 18.0 1.5 0.0 0.0 0.6 0.6 0.4 0.4 1.1 0.0 0.0 0.0 0.0 1.3 31.7 0.4 0.0 1.2 72.1 0.0 0.1 0.7 0.0 1.3 2.7 0.0 0.2 1.0 4.6 0.1 1.3 0.0 1.1 1.8 0.2 1.7 2.5 1.4 0.0 0.8 1.4 168.4 0.9 1.2 3.6 1.9 2.0 0.0 35.0 0.5 0.1 0.1 2.6 0.7 11.6 0.0 5.5 0.4 0.7 0.0 0.0 0.3 0.6 1.1 0.5 0.3 0.1 0.1 73.3 0.0 4.7 0.1 SCN2A "HBSCI, HBSCII, Nav1.2, SCN2A1, SCN2A2" ENSG00000136531 "Sodium voltage-gated channel alpha subunit 2" Q99250 2 165194993-165392310 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 26.1" "Group enriched" "Detected in some" 5 "Excitatory neurons: 440.4;Inhibitory neurons: 364.7;Oligodendrocyte precursor cells: 246.3" "Cancer enhanced" "Detected in single" "glioma: 1.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HSkMC: 2.1;U-138 MG: 3.4;U-266/84: 8.1;U-87 MG: 2.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022567 Enhanced NA NA "Cluster 6: Brain - Smell perception" "Cluster 16: U-266 - Nucleosome" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "CAB022567: " "unprognostic (1.16e-1)" "unprognostic (3.56e-4)" "unprognostic (5.28e-2)" "unprognostic (6.12e-3)" "unprognostic (2.97e-1)" "unprognostic (8.62e-3)" "unprognostic (1.18e-1)" "unprognostic (7.25e-3)" "unprognostic (1.40e-1)" "unprognostic (2.78e-1)" "unprognostic (1.32e-2)" "unprognostic (5.21e-2)" "unprognostic (3.44e-2)" "unprognostic (1.76e-1)" "unprognostic (1.05e-1)" "unprognostic (4.88e-2)" "unprognostic (2.14e-1)" 0.2 1.3 15.8 0.1 17.5 0.0 0.7 26.1 20.1 0.2 0.0 0.1 0.2 0.5 0.9 0.0 0.1 0.8 0.1 22.2 8.0 3.5 0.1 0.2 0.0 0.0 0.0 0.2 0.1 0.0 3.7 0.1 0.0 0.1 0.1 4.6 0.2 0.4 0.0 0.0 0.2 0.6 0.0 0.1 0.3 0.3 2.5 0.3 0.0 0.0 0.0 0.1 0.3 5.8 0.0 0.0 0.3 0.0 0.1 0.4 0.0 0.0 1.7 0.0 1.6 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.7 0.4 0.0 0.2 0.0 0.3 0.0 0.1 2.1 0.0 0.1 0.0 1.5 0.0 0.0 0.0 0.2 0.9 0.0 0.1 0.0 1.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.8 1.9 0.0 0.0 0.0 0.7 0.0 0.0 0.0 3.4 0.2 0.2 0.0 0.3 8.1 0.0 2.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.8 17.5 26.1 20.1 22.2 8.0 0.0 0.0 0.0 0.0 2.5 5.8 0.1 0.0 1.7 18.3 0.5 0.3 0.1 0.2 0.0 49.8 0.3 4.7 0.8 0.0 0.0 11.0 47.9 0.1 0.2 0.0 5.9 0.2 1.6 0.1 2.3 0.3 0.0 0.0 440.4 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 15.2 364.7 0.0 0.0 0.0 0.0 1.4 1.2 0.0 0.0 60.9 0.0 3.4 0.0 246.3 17.0 0.3 0.0 6.0 0.0 0.0 0.0 0.3 0.0 4.3 0.0 0.0 0.6 0.0 0.9 0.1 0.1 0.0 0.4 1.0 0.0 0.0 SCN4A "HYKPP, HYPP, Nav1.4, SkM1" ENSG00000007314 "Sodium voltage-gated channel alpha subunit 4" P35499 17 63938554-63972918 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Congenital myasthenic syndrome, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "skeletal muscle: 137.4;tongue: 54.0" "Cell type enriched" "Detected in some" 6 "Adipocytes: 46.4" "Cancer enhanced" "Detected in some" "thyroid cancer: 2.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "REH: 15.0;RH-30: 45.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA053992 Approved "Nucleoplasm,Centriolar satellite" NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "Centriolar satellite" "HPA053992: AB_2797249" "unprognostic (2.47e-1)" "unprognostic (1.74e-1)" "unprognostic (1.57e-2)" "unprognostic (1.78e-3)" "unprognostic (2.80e-2)" "unprognostic (1.63e-2)" "unprognostic (3.87e-4)" "unprognostic (3.84e-3)" "unprognostic (1.61e-1)" "unprognostic (1.36e-1)" "unprognostic (1.59e-3)" "unprognostic (3.15e-2)" "unprognostic (2.70e-2)" "unprognostic (4.38e-3)" "unprognostic (3.46e-1)" "unprognostic (4.15e-1)" "unprognostic (6.45e-2)" 17.9 0.7 0.0 0.2 0.1 0.0 16.0 0.3 0.1 0.1 0.0 1.1 0.0 0.1 0.0 1.1 0.2 0.3 0.8 0.0 0.0 0.7 0.1 0.0 0.4 0.0 0.0 0.2 0.2 0.7 1.5 0.1 0.0 0.5 0.1 0.0 1.8 0.0 137.4 0.7 0.3 0.0 0.0 0.8 0.5 1.7 0.0 0.2 4.3 54.0 0.1 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 1.5 0.0 0.0 15.0 45.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 2.8 1.4 1.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 46.4 0.0 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.2 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.5 0.0 0.0 2.3 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.1 0.0 1.1 2.2 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 4.6 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 7.1 5.9 0.3 0.3 0.0 0.1 0.0 0.1 0.0 0.0 0.0 SCN9A "ETHA, Nav1.7, NE-NA, NENA, PN1" ENSG00000169432 "Sodium voltage-gated channel alpha subunit 9" Q15858 2 166195185-166376001 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 21.9" "Cell type enhanced" "Detected in many" "dendritic cells: 43.2;Hofbauer cells: 67.5;Inhibitory neurons: 48.2;Langerhans cells: 42.8;Oligodendrocyte precursor cells: 133.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 16 "plasmacytoid DC: 23.6" "Lineage enriched" "Detected in single" 26 "dendritic cells: 23.6" "Cell line enhanced" "Detected in many" "BJ: 23.0;BJ hTERT+: 16.8;HHSteC: 19.0;hTERT-RPE1: 15.6" "Region enriched" "Detected in many" 5 "hypothalamus: 9.3" "Low region specificity" "Detected in many" "CAB013679, HPA061843" Uncertain Approved "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane, Actin filaments, Focal adhesion sites" "CAB013679: , HPA061843: AB_2684625" "unprognostic (2.10e-1)" "unprognostic (2.83e-1)" "unprognostic (1.13e-1)" "unprognostic (8.98e-5)" "unprognostic (1.47e-3)" "unprognostic (9.43e-3)" "unprognostic (2.28e-2)" "unprognostic (2.24e-1)" "unprognostic (2.23e-1)" "unprognostic (3.64e-1)" "unprognostic (1.45e-1)" "unprognostic (2.27e-1)" "prognostic unfavorable (2.30e-5)" "unprognostic (1.69e-3)" "unprognostic (6.74e-2)" "unprognostic (2.46e-2)" "unprognostic (2.46e-1)" 1.7 1.7 5.3 0.9 4.2 2.0 0.6 0.1 3.4 0.6 0.0 3.2 0.5 0.2 0.1 0.5 0.4 1.2 0.4 2.9 21.9 1.7 3.9 2.0 0.6 8.2 19.4 0.3 2.0 0.1 1.5 4.3 12.0 0.3 3.1 0.7 0.4 0.4 0.2 0.7 1.8 2.4 2.2 3.1 0.4 5.1 18.2 1.6 0.3 0.6 0.4 0.5 0.5 1.7 0.0 2.5 0.1 0.0 9.6 7.9 0.0 23.0 16.8 5.2 1.7 0.5 0.1 0.0 0.0 2.8 0.2 0.1 6.5 0.6 8.6 0.0 2.1 1.7 1.8 1.9 19.0 0.1 0.0 0.6 0.2 9.1 1.7 15.6 1.1 1.2 6.1 6.6 0.8 0.0 3.6 0.0 1.9 0.1 0.6 0.8 3.3 9.0 2.4 9.5 1.0 9.5 0.0 0.1 0.3 4.8 0.3 0.0 0.1 0.0 1.5 0.1 0.4 0.1 0.1 0.0 3.2 0.0 2.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.9 0.5 0.1 23.6 0.0 0.1 5.3 4.2 0.1 3.4 2.9 21.9 8.2 19.4 12.0 2.2 18.2 1.7 0.9 12.8 23.8 0.7 1.3 1.0 0.4 0.5 0.6 0.6 0.8 0.9 2.5 8.6 4.4 5.5 0.0 0.3 43.2 9.0 3.9 23.4 2.5 0.1 0.1 5.7 33.0 4.2 15.8 31.5 0.3 2.0 0.0 0.1 3.8 18.1 13.6 9.5 67.5 0.0 48.2 19.3 10.2 1.9 42.8 3.2 1.2 11.3 3.6 2.8 1.0 2.3 0.0 133.7 0.4 12.7 7.8 0.0 1.2 0.3 14.7 11.5 2.2 0.2 0.0 7.8 1.6 1.3 0.4 0.5 0.4 1.1 0.9 4.4 12.9 0.2 SCRN1 KIAA0193 ENSG00000136193 "Secernin 1" Q12765 7 29920104-29990289 "Enzymes, Predicted intracellular proteins" Exocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 159.0" "Cell type enhanced" "Detected in many" "Muller glia cells: 80.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "WM-115: 326.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024517 Enhanced Approved Cytosol No No 160000 "Cluster 51: Monocytes - Innate immune response" "Cluster 77: Retina - Visual perception" "Cluster 17: WM-115 - Nervous system development" "Cluster 5: Muller glia cells - Visual perception" Cytosol "HPA024517: AB_2184811" "prognostic unfavorable (8.32e-4)" "prognostic unfavorable (8.46e-4)" "unprognostic (1.45e-1)" "prognostic unfavorable (4.00e-5)" "unprognostic (1.87e-2)" "unprognostic (2.43e-1)" "unprognostic (1.13e-3)" "unprognostic (1.10e-1)" "unprognostic (2.29e-1)" "prognostic unfavorable (7.27e-4)" "unprognostic (1.09e-2)" "unprognostic (1.02e-1)" "prognostic favorable (1.15e-5)" "unprognostic (2.57e-2)" "unprognostic (2.10e-1)" "unprognostic (2.23e-1)" "prognostic unfavorable (2.60e-4)" 13.9 27.9 112.4 13.1 118.9 8.1 14.3 128.2 117.9 22.2 52.2 27.5 6.5 27.4 16.2 19.0 26.0 16.5 19.8 112.5 129.0 23.7 2.6 16.4 14.3 112.5 159.0 32.4 36.7 54.5 34.0 15.8 115.5 27.9 10.4 102.5 18.0 37.2 2.4 11.1 15.8 34.3 116.1 10.8 19.3 23.0 122.5 28.9 13.5 11.0 21.6 22.0 17.8 127.1 106.3 75.0 119.9 48.6 83.1 126.9 0.5 97.0 128.8 102.5 110.0 87.1 81.8 13.0 83.7 124.7 227.3 46.7 137.7 41.2 148.9 0.6 29.0 43.8 49.7 56.6 105.9 0.3 0.5 106.5 58.1 93.5 49.6 139.4 95.9 28.0 0.5 33.3 146.6 59.5 15.5 0.1 109.4 0.2 79.6 0.3 127.7 1.1 71.7 51.5 43.7 103.1 99.9 64.1 112.5 149.7 86.3 6.9 106.7 132.2 113.3 1.7 123.7 10.8 177.0 1.1 62.4 0.5 326.5 3.7 3.4 10.3 0.9 14.1 10.7 14.0 0.2 1.0 10.9 7.6 0.7 1.4 0.5 7.1 25.4 10.8 0.0 3.5 112.4 118.9 128.2 117.9 112.5 129.0 112.5 159.0 115.5 116.1 122.5 127.1 5.9 28.9 14.1 42.7 15.4 3.1 12.6 14.0 14.2 66.9 7.6 5.2 15.8 20.0 22.3 33.1 45.9 0.4 16.2 1.1 15.6 24.1 61.1 7.3 11.9 10.9 12.1 2.5 52.0 25.1 1.9 17.2 5.6 6.7 8.2 22.9 1.8 0.3 5.4 69.0 51.4 0.7 14.2 8.8 13.9 68.1 13.7 11.1 7.2 16.9 11.5 80.8 12.3 31.2 35.6 21.2 17.3 21.1 12.5 17.4 0.1 2.8 29.2 41.1 6.6 9.6 11.9 3.1 11.0 5.1 1.7 1.0 2.8 8.5 1.2 22.3 SCRT1 "DKFZp547F072, ZNF898" ENSG00000261678 "Scratch family transcriptional repressor 1" Q9BWW7 8 144330565-144336482 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "brain: 64.2" "Cell type enhanced" "Detected in some" "Bipolar cells: 41.2;Early spermatids: 55.6;Excitatory neurons: 10.6;Horizontal cells: 35.3;Inhibitory neurons: 14.2;Late spermatids: 11.2" "Cancer enriched" "Detected in single" 5 "glioma: 1.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "SCLC-21H: 4.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045265 Uncertain Supported "Nuclear bodies" NA NA "Cluster 65: Brain - Ion transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 29: Early spermatids - Spermatogenesis" "Nuclear bodies" "HPA045265: AB_10959521" "unprognostic (7.70e-2)" "unprognostic (7.97e-2)" "unprognostic (6.96e-3)" "unprognostic (6.88e-4)" "unprognostic (2.43e-2)" "unprognostic (1.52e-1)" "unprognostic (4.05e-2)" "unprognostic (1.97e-1)" "unprognostic (8.02e-3)" "unprognostic (1.30e-1)" "unprognostic (1.83e-4)" "unprognostic (5.02e-2)" "unprognostic (7.05e-2)" "unprognostic (2.78e-1)" "unprognostic (2.35e-1)" "unprognostic (2.66e-3)" "unprognostic (1.04e-1)" 0.0 0.5 3.4 0.0 4.8 0.0 0.0 12.5 64.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 19.4 0.0 0.0 0.0 0.0 22.9 8.5 0.0 0.3 0.0 3.4 0.0 18.1 0.0 0.0 3.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 2.4 26.2 0.0 0.0 0.0 0.0 0.0 0.0 23.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 4.8 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 4.8 12.5 64.2 1.6 19.4 22.9 8.5 18.1 0.1 26.2 23.6 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 41.2 0.0 0.1 1.6 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 55.6 0.0 0.0 0.3 0.0 0.0 10.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 35.3 14.2 0.0 0.0 0.0 0.0 11.2 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.5 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.1 1.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 SDC1 "CD138, SDC, SYND1, syndecan" ENSG00000115884 "Syndecan 1" P18827 2 20200797-20225433 "Cancer-related genes, CD markers, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 491.6;liver: 484.7;skin 1: 447.4" "Cell type enhanced" "Detected in many" "Cholangiocytes: 267.4;Hepatocytes: 603.1;Squamous epithelial cells: 246.6;Syncytiotrophoblasts: 250.8;Urothelial cells: 492.8" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in many" 7 "midbrain: 17.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 482.2;hTCEpi: 436.6;U-251 MG: 470.0;U-266/70: 467.4;U-266/84: 1069.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "CAB002424, HPA006185, HPA067477" Enhanced Approved "Focal adhesion sites" "Secreted to blood" NA NA 63100000 3100000 "Cluster 43: B-cells - Humoral immune response" "Cluster 37: Intestine - Unknown function" "Cluster 16: U-266 - Nucleosome" "Cluster 22: Epithelial cell types - Mixed function" "Focal adhesion sites" "CAB002424: AB_442050, HPA006185: AB_1857705, HPA067477: " "prognostic unfavorable (2.22e-4)" "unprognostic (6.80e-3)" "unprognostic (6.80e-2)" "unprognostic (7.84e-2)" "prognostic unfavorable (5.02e-4)" "unprognostic (1.15e-1)" "unprognostic (4.02e-2)" "unprognostic (6.32e-2)" "unprognostic (1.70e-1)" "unprognostic (3.66e-1)" "unprognostic (2.27e-3)" "unprognostic (1.79e-1)" "unprognostic (1.63e-1)" "unprognostic (1.94e-2)" "unprognostic (4.27e-1)" "unprognostic (1.62e-2)" "unprognostic (1.52e-1)" 2.4 17.4 0.7 17.2 0.2 1.2 23.8 2.3 0.8 127.2 0.7 61.8 75.8 2.2 19.9 491.6 10.5 77.1 0.6 0.3 2.0 99.5 484.7 59.6 7.3 0.6 17.3 1.6 16.6 5.4 2.0 32.6 0.8 56.3 33.3 0.7 85.8 25.9 1.6 447.4 53.6 2.2 0.2 20.1 87.3 3.3 2.5 5.1 18.3 0.0 43.2 104.8 242.1 0.1 252.6 137.6 42.7 108.1 11.6 1.6 134.9 68.7 65.4 62.7 52.8 29.5 148.9 0.3 24.8 48.8 34.8 241.4 19.0 482.2 41.8 1.3 12.5 0.0 12.2 150.2 10.3 11.0 1.0 6.4 436.6 56.5 132.9 87.2 6.9 0.0 6.4 94.7 34.0 149.6 0.6 2.6 38.7 189.6 263.1 5.3 15.7 189.9 80.5 370.0 12.4 99.7 51.9 342.4 15.2 17.1 34.5 2.8 10.7 246.9 78.6 9.2 470.0 467.4 1069.8 1.0 74.5 0.6 28.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.2 2.3 0.8 0.3 2.0 0.6 17.3 0.8 0.2 2.5 0.1 0.4 93.0 99.0 0.0 33.0 113.9 189.1 162.8 81.4 0.6 29.9 26.7 0.9 267.4 161.8 42.3 0.0 3.8 0.7 147.2 31.3 61.3 0.1 16.6 5.0 3.5 10.8 13.5 0.3 21.8 46.3 5.0 55.0 22.9 6.3 7.5 7.5 603.1 2.3 21.9 0.2 73.1 50.8 10.6 11.9 0.3 0.6 2.5 21.4 0.0 0.6 0.3 0.0 1.0 0.0 111.4 78.0 1.2 165.1 78.0 106.5 88.5 43.4 0.4 0.0 0.1 15.0 1.0 14.0 246.6 229.0 250.8 4.0 0.1 85.1 492.8 SDHAF2 "C11orf79, FLJ20487, PGL2, SDH5" ENSG00000167985 "Succinate dehydrogenase complex assembly factor 2" Q9NX18 11 61430042-61446733 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" Chaperone "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039464, HPA039732" Supported Approved Nucleoli,Mitochondria,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" "Mitochondria, Cytosol" Nucleoli "HPA039464: AB_10962146, HPA039732: AB_10962868" "unprognostic (5.31e-2)" "unprognostic (1.12e-2)" "unprognostic (3.13e-1)" "unprognostic (1.30e-2)" "unprognostic (1.40e-1)" "unprognostic (6.71e-2)" "unprognostic (1.98e-3)" "unprognostic (9.06e-2)" "unprognostic (2.17e-1)" "unprognostic (2.09e-3)" "unprognostic (4.21e-3)" "unprognostic (1.50e-1)" "unprognostic (1.81e-2)" "unprognostic (3.61e-1)" "unprognostic (1.78e-1)" "unprognostic (1.45e-1)" "unprognostic (4.48e-2)" 27.5 37.1 36.2 26.4 37.4 45.6 28.9 37.9 38.2 23.8 37.4 27.2 24.7 23.8 34.8 28.8 28.7 25.5 40.4 35.9 40.2 36.5 46.4 23.8 39.9 37.9 37.6 26.9 24.0 32.9 41.0 24.9 37.9 29.0 29.1 23.4 26.3 20.9 38.9 26.3 27.0 26.9 37.7 34.7 27.6 22.1 38.0 38.0 28.6 44.7 41.6 32.8 21.7 39.2 45.0 58.4 36.5 25.1 57.2 52.2 27.0 33.3 58.0 48.9 41.8 52.8 46.8 42.3 58.4 55.6 62.8 45.4 45.4 51.4 56.6 60.4 39.7 33.2 35.5 71.9 52.8 41.4 48.1 55.6 58.7 50.2 45.8 35.3 80.8 43.5 42.2 50.9 63.5 86.0 49.2 89.3 56.1 47.0 78.6 45.9 45.9 76.6 63.7 57.9 36.9 40.6 46.9 53.5 99.0 38.5 83.0 40.2 53.3 45.0 32.7 54.3 37.5 31.2 51.2 54.7 43.4 37.3 46.0 125.3 68.8 126.6 82.5 64.5 103.1 89.7 93.0 91.7 55.9 84.8 101.5 97.5 97.9 97.9 53.3 63.3 126.7 78.6 36.2 37.4 37.9 38.2 35.9 40.2 37.9 37.6 37.9 37.7 38.0 39.2 32.8 35.3 33.2 11.1 28.9 20.6 34.6 53.7 10.2 14.0 27.9 35.1 22.3 14.3 33.5 29.5 6.2 77.0 41.9 29.5 54.8 55.3 15.8 19.3 21.7 36.5 34.2 30.3 13.2 60.3 51.4 28.4 16.8 19.0 32.3 22.2 42.5 42.3 52.7 15.2 13.3 31.4 59.0 36.5 22.8 17.8 31.4 29.7 44.4 8.4 66.4 49.4 69.0 16.6 18.1 62.9 34.9 30.9 16.3 30.8 34.0 51.9 31.5 19.7 32.9 17.3 27.2 23.1 25.8 10.9 22.4 99.6 41.5 45.1 27.6 38.8 SDHB "SDH, SDH1" ENSG00000117118 "Succinate dehydrogenase complex iron sulfur subunit B" P21912 1 17018722-17054032 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Electron transport, Transport, Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 491.5;tongue: 580.6" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 405.5;Proximal tubular cells: 449.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002868, CAB009822, CAB068233, CAB068234, CAB068235" Enhanced Supported "Nucleoplasm,Plasma membrane,Mitochondria" "Intracellular and membrane" NA NA 7900 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "Nucleoplasm, Plasma membrane" "CAB009822: AB_2183458, CAB068233: AB_2665638, CAB068234: AB_2665639, CAB068235: AB_2665640, HPA002868: AB_1079889" "unprognostic (1.06e-1)" "unprognostic (2.86e-2)" "unprognostic (2.19e-2)" "unprognostic (2.93e-2)" "unprognostic (1.88e-1)" "unprognostic (2.79e-3)" "unprognostic (1.58e-1)" "unprognostic (3.02e-1)" "unprognostic (1.19e-1)" "unprognostic (8.45e-2)" "unprognostic (5.51e-2)" "unprognostic (3.93e-2)" "prognostic favorable (2.93e-7)" "unprognostic (1.46e-1)" "unprognostic (2.75e-1)" "unprognostic (7.82e-2)" "unprognostic (3.82e-2)" 85.8 95.7 68.0 59.0 72.2 94.6 68.7 80.6 84.3 56.8 81.1 134.3 163.0 56.0 71.0 77.4 59.8 48.0 302.8 69.9 76.9 228.0 336.1 56.1 75.3 74.8 71.4 44.4 80.3 144.3 42.8 57.6 73.8 55.7 132.4 62.9 74.0 60.5 491.5 55.6 121.9 70.4 73.9 60.5 92.8 64.4 74.9 62.7 64.3 580.6 84.2 71.3 52.0 78.9 157.3 152.7 72.2 107.8 141.6 135.2 95.9 122.4 145.2 254.3 227.7 216.8 183.1 206.8 159.3 156.4 176.1 180.1 290.7 226.8 284.8 128.7 280.6 183.4 149.2 168.2 172.8 276.0 135.6 140.4 154.9 224.5 370.1 138.7 183.6 176.5 165.2 236.9 179.6 129.5 182.4 175.1 70.4 224.6 302.6 146.1 142.5 265.4 252.4 88.7 157.5 86.0 172.3 216.3 392.3 76.4 131.1 169.1 94.9 115.8 131.0 206.4 176.0 98.9 133.3 198.6 170.4 438.5 128.3 68.7 149.8 149.5 71.4 206.5 70.7 89.9 81.0 77.5 186.8 81.1 73.5 74.8 174.3 85.3 185.7 89.3 113.8 116.1 68.0 72.2 80.6 84.3 69.9 76.9 74.8 71.4 73.8 73.9 74.9 78.9 48.2 64.1 47.4 20.9 57.4 52.1 93.3 199.8 40.5 31.5 45.2 49.4 405.5 101.5 97.0 47.8 14.6 107.1 48.3 176.1 354.1 134.3 220.3 48.7 38.2 54.7 48.6 77.3 27.7 149.2 142.2 62.0 46.9 45.5 66.6 39.9 46.8 226.0 177.4 37.0 32.1 103.1 116.0 88.7 67.9 30.5 57.8 78.4 64.0 29.0 123.1 78.3 48.4 15.6 24.6 111.5 218.3 67.7 62.2 74.4 300.5 449.0 79.8 53.8 39.5 57.1 191.6 148.9 71.5 72.9 54.6 121.8 46.8 69.3 162.0 110.9 SEC14L6 ENSG00000214491 "SEC14 like lipid binding 6" B5MCN3 22 30522799-30546682 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "epididymis: 21.2;parathyroid gland: 30.5" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 12.8;Alveolar cells type 2: 10.5;Cholangiocytes: 11.5;Collecting duct cells: 12.9;Ductal cells: 6.6;Muller glia cells: 18.6" "Cancer enriched" "Detected in many" 7 "renal cancer: 12.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "K-562: 12.3;RPTEC TERT1: 21.8;SiHa: 6.6" HPA067695 Approved Nucleoplasm NA NA "Cluster 35: T-regs - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 5: Muller glia cells - Visual perception" Nucleoplasm "HPA067695: AB_2685889" "unprognostic (3.49e-2)" "unprognostic (4.76e-2)" "unprognostic (4.79e-2)" "unprognostic (4.09e-2)" "unprognostic (3.04e-2)" "unprognostic (1.12e-1)" "unprognostic (7.28e-3)" "unprognostic (3.88e-2)" "unprognostic (3.13e-1)" "unprognostic (3.35e-1)" "unprognostic (1.29e-1)" "unprognostic (9.25e-2)" "unprognostic (8.69e-2)" "unprognostic (8.20e-2)" "unprognostic (2.12e-1)" "unprognostic (2.48e-2)" "unprognostic (6.02e-2)" 1.4 1.4 5.3 0.3 4.6 2.1 3.9 4.5 4.7 3.5 5.9 0.5 0.6 3.2 21.2 0.3 1.7 4.5 0.3 4.4 5.0 8.4 0.4 11.9 0.4 8.6 6.2 2.4 5.5 30.5 2.5 0.5 8.8 1.7 0.3 5.0 0.4 2.6 0.2 10.0 0.5 2.2 5.2 0.4 1.2 5.4 8.7 0.3 0.3 0.8 0.6 0.4 0.4 4.9 0.2 0.1 0.9 0.3 0.0 0.0 1.0 0.1 0.0 0.1 0.0 0.2 0.5 0.3 1.1 0.1 0.1 0.2 0.1 0.0 0.3 0.0 0.0 3.0 0.3 0.3 0.1 0.2 0.4 0.0 0.1 0.1 0.1 0.7 0.0 0.1 12.3 0.2 0.0 0.5 0.1 0.4 0.5 0.0 0.1 0.2 0.0 0.1 21.8 0.2 0.2 0.1 6.6 0.1 0.0 0.2 1.8 0.0 0.0 0.2 0.1 0.2 0.1 0.1 0.1 0.2 0.0 0.3 0.1 0.5 0.1 0.1 0.1 0.1 0.3 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.4 0.3 0.1 0.1 0.5 0.0 5.3 4.6 4.5 4.7 4.4 5.0 8.6 6.2 8.8 5.2 8.7 4.9 0.0 12.8 10.5 0.3 0.2 0.1 0.5 0.0 0.0 0.2 0.4 0.5 0.3 11.5 3.7 12.9 0.0 0.0 0.0 0.0 1.9 6.6 0.0 0.3 0.4 1.0 0.0 0.0 0.7 0.8 0.0 0.2 0.0 1.5 1.3 0.2 0.7 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.3 0.3 0.1 0.0 0.0 0.6 18.6 0.0 1.5 0.6 1.8 0.0 0.7 0.0 0.1 0.0 2.9 0.0 0.5 0.0 2.7 0.1 0.9 0.4 0.0 0.0 0.1 0.9 0.0 0.0 0.2 SEC16A "KIAA0310, p250, Sec16L" ENSG00000148396 "SEC16 homolog A, endoplasmic reticulum export factor" O15027 9 136440096-136483759 "Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005684 Supported Supported "Endoplasmic reticulum,Golgi apparatus" NA NA 48000 "Cluster 27: Non-specific - Gene expression" "Cluster 29: Non-specific - Vesicular transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 27: Mucus-secreting cells - Mucin production" "Golgi apparatus" "Endoplasmic reticulum" "HPA005684: AB_1079189" "unprognostic (1.24e-3)" "unprognostic (2.07e-1)" "unprognostic (2.02e-1)" "prognostic favorable (1.30e-6)" "unprognostic (1.97e-1)" "unprognostic (1.72e-1)" "unprognostic (1.67e-1)" "unprognostic (3.84e-2)" "unprognostic (3.48e-1)" "unprognostic (5.30e-2)" "unprognostic (1.38e-3)" "unprognostic (4.75e-1)" "prognostic favorable (4.47e-4)" "unprognostic (5.57e-3)" "unprognostic (2.64e-1)" "unprognostic (2.47e-2)" "unprognostic (1.41e-1)" 16.8 18.2 6.4 16.6 6.7 35.3 17.1 8.0 9.4 16.6 19.3 17.3 14.9 17.9 9.0 17.9 16.4 12.4 14.5 7.0 5.2 14.3 37.9 19.4 16.9 4.4 4.9 16.2 29.2 14.0 24.3 10.8 3.5 18.7 10.5 9.2 25.8 13.1 23.5 19.7 19.1 10.7 2.4 20.7 27.2 17.6 5.2 17.4 15.3 11.9 12.3 15.9 14.5 5.0 26.5 57.7 28.5 47.2 29.6 30.3 33.6 32.1 27.9 23.4 17.8 41.9 22.1 26.4 22.1 39.2 28.8 71.3 31.8 46.2 12.7 56.2 20.7 26.9 55.1 33.7 28.6 46.2 45.8 32.8 32.5 32.7 38.1 18.9 32.2 34.5 34.1 35.6 25.0 114.3 31.2 24.9 25.1 79.0 40.4 44.3 35.2 45.0 23.8 35.0 40.0 26.6 41.6 62.2 19.8 13.8 63.6 35.9 47.0 37.6 28.1 30.8 25.2 16.9 27.7 33.4 29.2 20.6 38.3 1.7 2.8 1.2 2.5 3.1 2.7 2.3 2.6 3.0 1.6 1.4 1.6 2.8 2.0 1.5 3.4 2.6 1.9 2.4 6.4 6.7 8.0 9.4 7.0 5.2 4.4 4.9 3.5 2.4 5.2 5.0 20.0 25.6 41.7 16.6 16.4 24.9 15.3 18.4 10.8 20.2 38.7 30.6 11.5 12.8 23.6 12.9 25.0 8.1 17.5 30.1 7.9 14.2 5.1 26.9 19.5 18.2 40.7 12.0 27.4 16.4 11.8 16.0 46.9 38.2 23.5 25.4 17.9 62.2 16.5 33.7 19.2 65.5 20.3 23.4 19.5 6.0 13.1 22.3 14.2 17.8 19.5 13.0 11.3 9.5 14.7 22.8 14.7 16.6 25.1 26.3 22.3 10.1 34.7 17.1 13.1 20.5 16.6 24.4 16.1 17.2 26.9 15.1 17.8 15.8 22.8 22.1 SEC22A SEC22L2 ENSG00000121542 "SEC22 homolog A, vesicle trafficking protein" Q96IW7 3 123201927-123274136 "Predicted intracellular proteins, Predicted membrane proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 67.5;Inhibitory neurons: 67.5;Oligodendrocytes: 75.0;Spermatocytes: 75.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (2.94e-2)" "unprognostic (1.09e-2)" "unprognostic (1.96e-1)" "unprognostic (8.25e-3)" "unprognostic (2.16e-1)" "unprognostic (9.04e-2)" "unprognostic (1.13e-2)" "unprognostic (4.91e-2)" "unprognostic (6.59e-2)" "unprognostic (2.16e-1)" "unprognostic (2.05e-1)" "unprognostic (2.66e-3)" "prognostic unfavorable (2.48e-4)" "unprognostic (1.46e-1)" "unprognostic (1.61e-1)" "unprognostic (3.03e-2)" "unprognostic (5.25e-1)" 10.4 11.2 6.6 8.1 6.9 4.6 10.9 8.6 6.9 10.5 6.8 8.9 6.8 9.6 8.8 12.3 9.6 9.0 8.0 7.5 6.8 10.5 12.9 9.2 10.3 6.2 6.8 10.6 10.1 9.5 11.3 10.1 7.2 8.9 9.5 9.9 9.6 7.3 6.1 13.7 8.5 11.6 6.1 9.8 8.4 21.5 7.0 10.2 9.9 5.5 13.1 8.9 10.0 8.0 40.4 12.5 20.2 15.6 27.1 25.4 20.2 35.3 22.2 20.4 28.8 10.3 22.0 20.9 25.8 19.9 23.8 30.5 16.0 20.8 34.0 9.1 13.6 14.1 11.7 9.0 24.7 18.3 11.6 18.2 27.2 19.4 18.7 20.5 27.6 18.3 9.4 17.4 20.6 17.6 17.0 13.5 7.1 29.2 25.0 12.9 21.5 21.2 18.6 11.0 14.6 11.3 20.8 14.5 21.0 14.6 30.2 22.5 12.6 17.8 19.5 29.4 21.5 11.4 11.4 34.6 26.5 20.5 27.3 19.3 19.9 16.7 24.1 19.3 29.8 18.7 24.7 26.4 19.9 15.7 26.3 22.0 2.9 28.9 19.5 19.2 27.6 16.9 6.6 6.9 8.6 6.9 7.5 6.8 6.2 6.8 7.2 6.1 7.0 8.0 10.5 3.2 12.1 39.8 13.9 8.4 17.9 29.7 10.8 7.5 7.9 7.4 5.6 17.2 20.4 7.3 4.2 27.5 7.3 6.1 9.8 17.8 30.5 4.7 9.0 9.8 7.8 8.6 67.5 10.4 19.5 12.5 12.2 6.4 7.0 11.6 12.1 9.0 13.6 1.7 67.5 9.4 10.2 5.0 8.0 16.5 12.2 7.8 5.4 56.2 11.7 6.7 9.2 59.3 75.0 11.3 4.6 6.8 18.4 9.9 5.7 9.5 11.1 7.6 19.7 8.8 12.3 75.6 17.0 12.1 9.5 44.1 12.9 11.2 6.8 10.9 SEMA4D "C9orf164, CD100, coll-4, FLJ39737, SEMAJ" ENSG00000187764 "Semaphorin 4D" Q92854 9 89360787-89498130 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 260.2" "Cell type enhanced" "Detected in many" "dendritic cells: 76.5;NK-cells: 92.7;Oligodendrocytes: 310.5;T-cells: 89.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 133.2;HMC-1: 97.2;JURKAT: 89.1;MOLT-4: 120.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015662, HPA023277" Approved NA NA 7500000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA015662: AB_1856671, HPA023277: AB_1856672" "unprognostic (2.94e-2)" "prognostic favorable (4.17e-4)" "unprognostic (1.12e-2)" "unprognostic (8.22e-2)" "unprognostic (1.41e-1)" "unprognostic (1.76e-3)" "unprognostic (1.27e-1)" "unprognostic (1.58e-1)" "unprognostic (7.79e-2)" "unprognostic (2.74e-1)" "unprognostic (3.18e-3)" "unprognostic (1.50e-2)" "unprognostic (2.29e-3)" "unprognostic (3.05e-2)" "unprognostic (1.28e-2)" "unprognostic (2.43e-1)" "prognostic favorable (4.06e-5)" 7.2 12.8 73.5 35.1 149.7 28.7 6.1 129.0 122.7 9.1 34.2 10.4 10.6 6.5 12.2 27.3 11.0 12.3 12.1 72.0 88.4 32.0 4.1 14.2 62.4 165.2 145.6 6.5 8.0 6.0 13.8 5.5 147.8 11.9 9.7 5.0 12.0 6.6 88.0 17.4 28.9 5.5 119.1 51.3 16.7 10.6 127.0 43.4 11.8 27.5 49.8 11.4 16.2 260.2 12.7 9.2 8.4 12.4 0.4 0.8 19.0 1.1 0.5 2.6 1.7 6.1 13.8 47.3 5.1 0.2 9.7 6.4 7.5 3.6 1.1 133.2 7.5 20.1 3.3 0.7 1.5 26.4 97.2 0.3 2.8 0.6 0.3 0.3 4.9 89.1 4.8 31.5 0.0 20.9 120.9 33.9 20.6 25.0 0.5 38.2 2.8 13.4 16.5 13.0 19.7 13.1 3.4 8.9 0.3 11.7 10.1 14.4 3.2 0.1 7.6 1.0 6.1 34.9 16.3 6.6 6.0 32.1 7.6 17.2 7.5 38.2 22.0 7.0 13.3 4.3 17.5 18.6 2.6 2.5 19.9 23.2 37.0 9.4 8.1 8.0 17.7 14.5 73.5 149.7 129.0 122.7 72.0 88.4 165.2 145.6 147.8 119.1 127.0 260.2 3.4 6.4 15.7 33.6 35.4 4.6 3.3 2.1 3.4 12.4 9.5 5.5 18.7 5.7 6.9 11.0 2.1 9.0 76.5 1.5 3.9 5.4 2.2 10.9 6.4 5.2 1.8 23.1 44.5 3.3 2.1 6.7 7.7 15.4 42.5 8.0 5.3 1.6 21.6 33.7 17.2 6.3 4.1 28.2 6.1 3.8 7.5 37.4 1.8 49.6 43.7 8.9 92.7 12.1 310.5 3.7 0.7 15.1 53.7 6.5 0.5 14.2 5.7 5.1 0.0 11.4 2.6 0.9 26.1 7.1 5.4 3.7 89.7 2.3 3.3 7.7 SEMA6A "HT018, KIAA1368, SEMA, SEMA6A1, SEMAQ" ENSG00000092421 "Semaphorin 6A" Q9H2E6 5 116443555-116574823 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 60.1;brain: 75.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 128.9;Hepatic stellate cells: 145.6;Horizontal cells: 138.0;Oligodendrocyte precursor cells: 138.7;Oligodendrocytes: 311.3;Syncytiotrophoblasts: 348.1" "Cancer enhanced" "Detected in all" "testis cancer: 20.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 44.3;HAP1: 52.0;NTERA-2: 115.2;SuSa: 221.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031264, HPA031265, HPA031267" Approved Approved "Nucleoplasm,Nuclear bodies,Intermediate filaments" NA NA 620000 "Cluster 70: Brain - Nervous system development" "Cluster 12: NES - Nervous system development" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm "Nuclear bodies, Intermediate filaments" "HPA031264: , HPA031265: AB_10610423, HPA031267: " "unprognostic (3.79e-2)" "unprognostic (3.91e-1)" "unprognostic (1.82e-2)" "unprognostic (6.81e-2)" "unprognostic (2.69e-2)" "unprognostic (3.77e-1)" "prognostic unfavorable (4.39e-4)" "unprognostic (1.64e-1)" "unprognostic (4.71e-2)" "unprognostic (5.82e-2)" "unprognostic (1.92e-2)" "unprognostic (1.13e-1)" "unprognostic (2.24e-1)" "unprognostic (3.62e-3)" "unprognostic (1.92e-1)" "unprognostic (6.21e-3)" "unprognostic (7.32e-3)" 13.4 60.1 24.1 4.9 48.6 3.5 13.1 39.9 31.9 10.0 0.3 20.6 19.9 6.0 2.8 4.4 8.2 12.9 7.1 24.5 40.3 8.6 5.6 17.9 4.5 51.9 41.0 18.1 11.2 2.0 5.8 31.9 50.0 6.0 17.5 10.4 16.6 2.5 8.2 6.9 25.5 5.8 32.9 11.2 7.0 7.5 44.1 3.6 9.1 6.5 2.2 5.6 8.1 75.2 0.3 0.1 36.9 44.3 0.2 0.0 38.2 0.7 0.4 0.2 0.2 2.2 1.5 1.6 1.7 0.6 0.7 0.4 52.0 0.0 0.1 1.6 7.7 0.7 0.7 13.1 0.5 0.5 2.6 0.7 0.0 0.0 0.0 0.5 0.2 0.3 0.3 0.4 0.2 0.8 0.7 3.9 115.2 0.2 0.3 6.9 24.2 1.8 19.0 33.7 10.3 3.7 0.2 0.7 19.7 221.1 14.4 2.6 0.9 3.6 3.1 0.4 1.5 0.6 0.7 0.8 0.6 1.8 13.8 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 24.1 48.6 39.9 31.9 24.5 40.3 51.9 41.0 50.0 32.9 44.1 75.2 64.7 0.0 0.6 71.8 1.1 6.5 0.7 13.1 34.7 17.9 17.0 8.3 8.6 61.5 3.1 14.7 2.1 128.9 0.3 73.3 0.0 42.9 13.6 12.2 4.8 60.9 28.1 2.7 26.9 1.3 8.1 15.4 1.1 10.6 0.0 9.7 145.6 0.9 12.5 138.0 62.2 30.7 0.0 14.8 4.6 2.4 6.5 1.1 24.9 54.4 0.1 5.8 0.0 138.7 311.3 2.0 46.7 1.9 2.6 1.5 40.7 4.4 0.6 3.5 0.0 36.1 8.1 0.9 1.5 11.3 4.1 348.1 0.8 3.5 40.3 2.2 SEMA6B "SEM-SEMA-Y, SEMA-VIB, SEMAN, semaZ" ENSG00000167680 "Semaphorin 6B" Q9H3T3 19 4542593-4581776 "Disease related genes, Plasma proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 72.3" "Cell type enhanced" "Detected in many" "Adipocytes: 43.6;Alveolar cells type 1: 28.9;Alveolar cells type 2: 44.6;Endothelial cells: 40.1;Excitatory neurons: 30.6;granulocytes: 29.7;Hepatic stellate cells: 37.5;Inhibitory neurons: 30.3;Macrophages: 35.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 124.5;HMC-1: 198.1;HUVEC TERT2: 83.8;TIME: 107.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025157, HPA055778, HPA058523" Enhanced NA NA 1100000 "Cluster 10: Brain - Neuronal signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 11: Alveolar cells - Smell perception" "CAB025157: , HPA055778: AB_2682916, HPA058523: AB_2683741" "unprognostic (4.03e-1)" "unprognostic (9.69e-3)" "unprognostic (6.38e-3)" "unprognostic (2.15e-1)" "unprognostic (1.15e-1)" "unprognostic (7.94e-2)" "unprognostic (2.10e-1)" "unprognostic (4.34e-3)" "unprognostic (6.61e-2)" "unprognostic (1.90e-1)" "unprognostic (4.21e-2)" "unprognostic (2.82e-1)" "prognostic unfavorable (3.29e-5)" "unprognostic (1.26e-1)" "unprognostic (1.81e-2)" "prognostic unfavorable (1.45e-4)" "unprognostic (9.55e-2)" 25.6 19.7 44.0 11.0 30.7 7.8 17.1 0.6 72.3 8.7 0.0 6.6 4.0 10.6 0.4 3.6 8.8 5.8 20.2 65.2 12.4 13.3 2.9 10.7 1.2 13.5 11.0 3.3 4.1 9.2 7.2 8.9 1.8 7.0 1.0 1.4 3.9 1.3 6.0 4.6 7.3 6.9 0.5 31.9 6.1 1.9 30.2 0.7 9.1 4.3 0.7 10.0 6.7 17.4 7.2 25.0 2.3 21.4 0.1 1.2 0.2 0.0 0.7 2.4 0.6 0.2 2.0 0.0 23.7 0.0 3.8 4.4 6.5 0.0 0.9 0.1 1.0 0.0 0.4 124.5 0.4 0.0 198.1 7.5 0.1 0.2 0.2 24.9 83.8 0.1 1.6 0.3 0.7 6.5 0.0 0.0 26.8 1.7 0.3 0.4 46.8 0.6 1.7 0.1 17.7 1.7 0.1 1.7 11.5 1.8 2.7 1.1 107.8 3.1 34.7 0.5 18.6 1.3 0.0 0.4 0.8 1.3 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.0 30.7 0.6 72.3 65.2 12.4 13.5 11.0 1.8 0.5 30.2 17.4 43.6 28.9 44.6 2.6 2.3 4.7 1.5 0.5 0.0 9.0 2.1 1.9 1.9 1.5 19.3 1.8 4.2 0.6 2.3 0.2 0.0 1.1 1.1 1.1 2.5 40.1 0.0 8.4 30.6 0.2 0.6 8.2 0.0 2.0 29.7 0.5 37.5 6.0 3.3 18.5 30.3 0.1 0.0 6.1 18.1 0.4 0.6 35.2 7.2 7.5 1.4 2.0 1.0 19.1 1.4 0.2 0.1 0.7 1.1 1.2 0.0 0.4 17.7 4.1 0.0 8.8 1.8 2.0 2.2 0.0 5.1 0.3 5.4 1.6 0.1 0.9 SEMA7A "CD108, H-Sema-L, SEMAL" ENSG00000138623 "Semaphorin 7A (John Milton Hagen blood group)" O75326 15 74409289-74433958 "Blood group antigen proteins, CD markers, Plasma proteins, Predicted membrane proteins" "Differentiation, Inflammatory response, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 60.1;retina: 34.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 68.8;Extravillous trophoblasts: 58.8;Granulosa cells: 65.1;Pancreatic endocrine cells: 91.0;Rod photoreceptor cells: 58.3;Syncytiotrophoblasts: 166.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 1.8;eosinophil: 3.1" "Lineage enriched" "Detected in single" 5 "granulocytes: 3.1" "Cell line enhanced" "Detected in many" "HMC-1: 275.8;hTEC/SVTERT24-B: 108.7;U-251 MG: 166.3;U-87 MG: 92.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008210, HPA042273" Uncertain Uncertain Vesicles NA NA 38000000 "Cluster 52: Eosinophils - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Vesicles "HPA008210: , HPA042273: AB_10806234" "unprognostic (2.00e-1)" "unprognostic (2.72e-1)" "unprognostic (2.02e-2)" "unprognostic (5.81e-2)" "unprognostic (6.49e-2)" "unprognostic (8.61e-2)" "unprognostic (2.54e-2)" "unprognostic (4.18e-3)" "unprognostic (1.33e-1)" "unprognostic (1.39e-1)" "unprognostic (5.18e-3)" "unprognostic (1.44e-1)" "prognostic unfavorable (2.45e-11)" "unprognostic (1.32e-1)" "unprognostic (2.01e-2)" "unprognostic (6.25e-2)" "unprognostic (2.57e-2)" 2.0 2.5 4.6 7.0 11.0 9.9 1.9 19.1 14.4 2.2 0.9 2.4 1.5 2.9 0.9 4.8 1.4 1.8 2.3 5.1 8.2 2.8 1.6 8.1 13.2 19.9 11.6 7.8 0.9 1.9 2.7 16.3 22.9 1.8 0.9 34.6 2.2 1.2 2.0 8.5 10.8 1.1 10.6 60.1 3.5 29.5 17.2 9.4 1.3 0.3 12.9 8.2 2.5 20.2 16.7 0.2 4.8 1.4 6.0 20.1 39.7 75.2 30.1 15.5 23.8 6.5 26.6 0.1 4.3 34.2 12.6 4.9 1.5 4.8 16.0 1.3 0.9 30.0 0.1 8.3 1.3 0.9 275.8 14.3 0.2 108.7 6.0 39.0 0.2 2.0 17.5 10.1 51.2 1.4 4.3 9.9 5.2 0.4 11.3 0.6 3.3 4.4 6.5 7.1 0.3 0.5 0.5 13.4 6.1 4.1 1.0 6.0 3.0 28.8 19.2 14.1 166.3 1.8 1.3 0.3 92.4 3.4 1.5 1.8 0.0 3.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 4.6 11.0 19.1 14.4 5.1 8.2 19.9 11.6 22.9 10.6 17.2 20.2 1.8 3.2 0.0 1.0 22.6 0.4 1.6 3.1 0.6 13.7 1.2 1.3 1.4 0.0 4.0 1.8 68.8 25.6 5.2 0.6 0.0 19.8 0.5 4.6 1.5 5.3 0.0 21.7 12.4 13.9 58.8 1.8 1.5 10.6 8.2 65.1 0.7 0.7 7.2 1.7 5.9 0.0 0.0 0.3 12.0 2.5 3.7 4.8 8.8 0.0 28.6 6.8 1.0 4.0 16.3 91.0 0.1 1.9 6.4 3.3 0.1 0.1 2.0 58.3 0.0 0.2 9.0 0.9 0.8 0.2 1.4 166.4 5.7 22.0 0.0 24.4 SEPTIN10 "FLJ11619, SEPT10" ENSG00000186522 "Septin 10" Q9P0V9 2 109542799-109614143 "Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 56.4;Cardiomyocytes: 21.8;Cytotrophoblasts: 15.1;Extravillous trophoblasts: 59.4;Fibroblasts: 15.5;Hofbauer cells: 19.6;Smooth muscle cells: 11.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 3.5" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047860, HPA056304, HPA060310" Enhanced Supported "Actin filaments" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "Actin filaments" "HPA047860: AB_2680187, HPA056304: AB_2683094, HPA060310: AB_2684249" "unprognostic (1.84e-1)" "unprognostic (4.29e-3)" "unprognostic (1.94e-2)" "unprognostic (3.18e-2)" "unprognostic (6.34e-2)" "unprognostic (3.41e-2)" "unprognostic (2.02e-3)" "unprognostic (1.80e-2)" "unprognostic (9.67e-2)" "unprognostic (8.61e-2)" "unprognostic (1.78e-2)" "unprognostic (1.21e-1)" "unprognostic (1.58e-2)" "unprognostic (3.05e-3)" "unprognostic (2.72e-1)" "unprognostic (2.55e-1)" "unprognostic (9.12e-2)" 57.0 24.2 16.1 22.6 29.5 0.7 52.9 29.8 20.3 41.5 58.7 52.0 22.3 44.5 21.7 88.4 33.4 41.8 41.7 15.1 24.2 43.4 66.5 60.4 18.4 46.8 29.5 46.7 20.3 26.9 9.5 50.4 41.6 40.6 39.8 13.6 34.7 42.2 28.5 73.4 24.3 58.0 31.9 36.3 30.5 76.9 26.1 19.9 43.3 39.0 22.8 55.1 43.2 44.5 104.7 27.7 99.6 64.1 78.1 145.8 61.1 166.5 290.6 114.8 133.3 52.2 59.0 0.0 82.2 130.4 72.2 47.7 42.8 105.2 151.6 199.4 31.2 0.2 38.5 75.3 58.7 0.2 13.4 91.5 46.9 103.5 135.1 123.9 154.3 0.0 2.7 0.4 141.5 9.9 0.1 10.3 74.4 61.3 53.7 0.1 80.9 17.4 95.7 136.8 29.6 61.8 97.8 2.1 77.0 115.2 26.5 1.2 158.5 120.1 85.1 46.9 69.6 61.4 36.0 0.9 106.7 2.3 148.1 0.0 2.4 0.0 0.1 1.6 0.1 0.8 1.5 0.4 0.6 0.3 0.7 0.2 0.1 0.0 1.0 0.0 3.5 0.8 16.1 29.5 29.8 20.3 15.1 24.2 46.8 29.5 41.6 31.9 26.1 44.5 56.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.8 0.0 0.0 0.0 0.0 15.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.0 59.4 15.5 0.0 0.0 0.0 0.0 0.0 0.0 19.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.0 7.5 0.1 0.0 0.0 0.0 SEPTIN6 "KIAA0128, MGC16619, MGC20339, SEP2, SEPT2, SEPT6" ENSG00000125354 "Septin 6" Q14141 X 119615724-119693370 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Host-virus interaction, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 231.3" "Cell type enhanced" "Detected in some" "B-cells: 20.3;Cytotrophoblasts: 43.9;dendritic cells: 66.5;Extravillous trophoblasts: 50.1;Hofbauer cells: 54.8;Plasma cells: 28.4;Syncytiotrophoblasts: 43.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "JURKAT: 273.0;MOLT-4: 300.5;REH: 271.8;SH-SY5Y: 394.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003459, HPA005665" Supported Approved Cytosol NA NA 2900000 "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA003459: AB_1856696, HPA005665: AB_1079910" "unprognostic (6.35e-3)" "unprognostic (1.64e-3)" "unprognostic (1.38e-1)" "unprognostic (9.61e-2)" "unprognostic (1.15e-1)" "unprognostic (3.09e-1)" "unprognostic (1.73e-1)" "unprognostic (6.23e-2)" "unprognostic (2.13e-1)" "unprognostic (7.24e-2)" "unprognostic (6.27e-2)" "unprognostic (1.46e-1)" "unprognostic (1.95e-1)" "unprognostic (2.55e-1)" "unprognostic (2.88e-1)" "unprognostic (1.92e-1)" "unprognostic (2.60e-2)" 13.1 73.4 14.5 66.7 12.8 61.1 12.7 16.9 16.9 11.5 7.8 47.4 14.3 11.2 16.9 17.9 18.1 17.5 16.1 12.4 20.8 18.1 21.3 16.5 119.7 18.3 18.0 11.4 4.6 9.9 9.8 14.7 22.1 13.4 18.5 38.9 18.2 40.5 4.6 7.1 35.3 24.4 13.5 61.9 20.0 40.3 20.5 231.3 7.6 5.9 103.9 18.6 9.7 12.0 6.5 10.1 37.9 68.5 3.5 7.7 53.9 18.9 41.7 31.4 53.8 3.4 14.4 130.7 14.6 23.9 32.6 3.7 60.2 12.1 21.7 80.6 13.9 58.1 20.3 23.5 9.1 66.3 29.4 14.0 2.6 24.8 0.6 13.1 46.4 273.0 43.6 68.0 18.7 4.8 300.5 38.6 40.2 1.9 31.0 271.8 31.3 106.7 33.5 6.8 16.8 394.7 49.1 17.9 20.6 40.7 24.3 33.8 29.0 8.5 17.2 27.5 4.7 33.8 14.5 170.7 0.8 69.0 6.3 34.2 17.2 39.9 58.6 26.1 61.4 65.0 75.3 68.6 34.0 64.0 79.3 69.4 11.8 81.3 38.8 63.7 112.4 53.9 14.5 12.8 16.9 16.9 12.4 20.8 18.3 18.0 22.1 13.5 20.5 12.0 13.8 0.0 0.0 0.0 20.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 0.0 0.0 0.0 0.0 43.9 66.5 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 50.1 7.1 0.0 0.0 0.0 0.0 0.0 0.0 54.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 43.0 15.5 0.0 0.0 0.0 SEPTIN9 "AF17q25, KIAA0991, MSF, MSF1, PNUTL4, SEPT9, SeptD1" ENSG00000184640 "Septin 9" Q9UHD8 17 77280569-77500596 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 29.9;Cytotrophoblasts: 78.2;dendritic cells: 34.8;Extravillous trophoblasts: 152.8;Hofbauer cells: 67.5;Syncytiotrophoblasts: 70.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042564, HPA050627" Approved Enhanced "Actin filaments" No No 770000 "Cluster 39: Non-specific - mRNA processing" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Actin filaments" "HPA042564: AB_2678054, HPA050627: AB_2681193" "unprognostic (7.65e-2)" "unprognostic (5.44e-2)" "unprognostic (5.46e-3)" "unprognostic (2.34e-1)" "unprognostic (2.65e-2)" "unprognostic (2.71e-1)" "prognostic unfavorable (1.61e-5)" "unprognostic (4.23e-3)" "unprognostic (1.56e-1)" "unprognostic (8.48e-2)" "unprognostic (1.99e-1)" "unprognostic (2.45e-1)" "unprognostic (1.49e-2)" "unprognostic (1.25e-1)" "unprognostic (1.35e-1)" "unprognostic (1.33e-1)" "unprognostic (2.80e-1)" 68.7 87.9 58.8 148.8 61.7 89.2 72.8 81.6 85.3 99.3 59.9 137.8 94.9 127.5 27.0 81.9 89.0 88.3 70.5 68.1 68.6 75.2 99.5 77.8 223.8 111.5 62.0 76.4 38.7 67.2 63.3 80.7 76.6 96.0 51.9 15.6 76.8 75.6 73.1 80.3 145.1 84.5 68.2 152.8 103.1 60.0 65.7 260.2 52.9 43.1 151.5 122.9 82.4 71.8 246.1 342.0 221.3 186.4 257.0 417.1 121.7 188.9 214.1 122.4 89.0 278.4 243.4 338.7 153.4 388.5 161.2 149.1 96.6 354.8 90.4 6.2 65.0 128.8 147.3 483.2 212.0 84.6 218.3 215.6 128.8 159.6 136.0 180.3 167.5 196.4 144.6 44.1 110.7 258.1 628.1 72.0 207.5 281.4 281.1 290.7 192.6 117.1 197.5 337.9 171.0 324.3 214.2 349.6 207.2 248.6 260.2 60.7 243.6 165.8 147.6 197.4 130.2 10.5 19.5 562.6 245.6 73.7 348.7 4.2 18.4 31.1 22.3 46.3 19.0 16.3 28.7 26.4 17.0 17.4 29.6 25.8 6.1 16.9 55.3 38.7 31.8 24.9 58.8 61.7 81.6 85.3 68.1 68.6 111.5 62.0 76.6 68.2 65.7 71.8 29.9 0.0 0.0 0.0 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.5 0.0 0.0 0.0 0.0 78.2 34.8 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 152.8 9.4 0.0 0.0 0.0 0.0 0.0 0.0 67.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.0 0.0 0.0 0.0 70.6 6.8 0.0 0.0 0.0 SERBP1 "CGI-55, CHD3IP, DKFZP564M2423, HABP4L, PAI-RBP1, PAIRBP1" ENSG00000142864 "SERPINE1 mRNA binding protein 1" Q8NC51 1 67407810-67430415 "Plasma proteins, Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020559, CAB026297" Supported Enhanced Cytosol NA NA 810000 "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "CAB026297: AB_425924, HPA020559: AB_1856701" "unprognostic (1.58e-1)" "unprognostic (6.35e-2)" "unprognostic (1.45e-2)" "unprognostic (6.80e-3)" "unprognostic (2.71e-3)" "unprognostic (3.59e-1)" "prognostic unfavorable (1.36e-4)" "unprognostic (1.98e-2)" "unprognostic (1.32e-3)" "unprognostic (5.97e-2)" "unprognostic (8.25e-3)" "unprognostic (3.04e-1)" "unprognostic (1.33e-2)" "unprognostic (1.40e-2)" "unprognostic (4.76e-1)" "unprognostic (6.64e-2)" "unprognostic (1.34e-3)" 116.2 79.6 45.9 110.1 48.9 130.5 106.9 45.7 48.5 98.3 44.4 91.2 99.6 89.9 65.7 188.2 81.5 66.5 93.4 42.5 46.5 85.9 131.4 76.6 123.8 51.6 47.5 86.8 121.1 131.5 48.0 92.9 52.4 77.3 84.5 47.6 119.0 66.2 336.9 149.6 92.7 82.1 50.3 81.4 94.1 82.9 49.3 125.7 91.1 159.0 118.1 101.4 118.4 52.8 444.4 272.4 274.9 280.4 236.9 214.0 420.9 452.9 163.8 294.7 241.6 524.8 195.4 828.9 341.1 236.0 294.6 337.4 435.2 411.2 309.5 375.7 535.8 764.1 488.7 460.7 207.0 614.9 290.8 221.3 272.1 384.6 356.0 205.9 319.7 276.0 867.4 293.0 236.2 314.9 494.9 412.9 978.1 298.1 355.2 566.3 600.4 429.8 231.0 349.8 468.8 330.8 351.0 385.6 442.4 231.1 212.0 386.4 345.9 283.4 351.5 421.2 618.3 273.6 369.2 747.9 233.0 603.3 326.9 37.8 84.1 53.7 100.4 92.5 125.4 101.3 99.0 100.9 107.5 102.1 114.6 105.6 27.1 147.4 90.1 98.2 131.5 119.2 45.9 48.9 45.7 48.5 42.5 46.5 51.6 47.5 52.4 50.3 49.3 52.8 251.3 250.0 225.5 17.6 262.6 686.4 437.3 363.8 536.7 146.7 262.1 251.8 144.8 214.4 311.4 117.7 91.8 271.5 343.7 200.0 242.6 324.4 555.9 368.1 411.9 314.9 230.1 398.8 24.1 361.5 531.0 231.0 169.7 400.5 219.2 215.6 179.2 331.5 297.9 143.0 24.6 338.7 183.1 247.7 281.2 240.9 221.2 214.2 192.1 27.2 298.4 153.6 325.4 26.7 33.2 349.3 192.0 278.7 277.4 540.5 168.4 323.0 206.3 139.7 138.1 301.6 516.0 569.8 281.6 597.9 719.7 229.3 271.4 318.8 405.0 470.2 SERGEF "DelGEF, Gnefr" ENSG00000129158 "Secretion regulating guanine nucleotide exchange factor" Q9UGK8 11 17788048-18013047 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 155.4;Excitatory neurons: 114.9;Inhibitory neurons: 123.9;Late spermatids: 258.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037811, HPA037812, HPA074086" Supported Enhanced Nucleoplasm,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 34: Spermatids - Unknown function" Nucleoplasm Cytosol "HPA037811: AB_10672726, HPA037812: AB_2675680, HPA074086: AB_2686658" "unprognostic (2.67e-2)" "unprognostic (7.15e-2)" "unprognostic (7.00e-2)" "unprognostic (9.04e-3)" "prognostic unfavorable (5.67e-4)" "unprognostic (6.94e-2)" "unprognostic (1.30e-3)" "unprognostic (1.87e-1)" "unprognostic (3.69e-2)" "unprognostic (1.70e-1)" "unprognostic (3.74e-3)" "unprognostic (5.56e-2)" "unprognostic (4.19e-1)" "unprognostic (1.89e-1)" "unprognostic (1.43e-1)" "unprognostic (1.24e-2)" "unprognostic (5.82e-2)" 16.1 17.5 35.9 9.4 37.4 6.4 16.4 49.6 42.8 19.5 32.2 25.4 7.4 16.8 18.4 12.5 16.5 9.9 18.9 39.0 39.1 19.6 14.0 14.0 10.7 37.4 53.9 27.5 23.1 17.1 36.8 5.7 43.8 21.3 12.3 22.5 15.1 18.0 22.7 20.2 13.8 16.4 34.8 12.8 19.7 5.0 37.3 12.3 27.7 21.7 13.5 21.5 17.7 39.1 10.8 13.2 10.6 22.3 19.1 18.6 7.2 9.0 18.3 9.5 12.0 8.5 3.7 9.5 11.0 12.2 26.1 14.5 37.3 27.6 7.5 21.0 37.7 15.3 10.6 36.3 21.5 13.5 16.6 17.7 27.4 4.8 20.4 28.6 10.5 20.8 9.2 17.6 15.2 16.0 14.0 30.0 8.9 33.7 16.2 18.3 13.0 10.0 21.2 16.1 27.1 5.9 15.8 16.1 17.1 21.1 7.2 12.1 6.2 8.9 12.1 13.1 10.2 12.3 16.1 12.9 15.5 15.4 10.2 15.6 21.3 17.1 34.5 17.6 28.6 25.5 35.5 25.8 26.1 18.7 34.8 30.5 2.3 22.4 17.5 10.5 41.4 25.9 35.9 37.4 49.6 42.8 39.0 39.1 37.4 53.9 43.8 34.8 37.3 39.1 12.7 6.4 6.8 58.4 14.3 26.5 25.3 30.5 15.9 14.1 18.5 20.8 11.6 10.0 13.6 11.0 2.1 6.4 14.4 7.8 39.2 17.1 155.4 3.3 5.1 9.0 48.5 7.4 114.9 24.5 12.5 14.4 4.6 5.2 14.5 26.7 12.5 14.7 14.3 11.8 123.9 14.7 34.6 17.8 14.9 258.3 19.6 9.3 21.4 44.0 12.9 31.7 17.5 82.9 46.5 14.0 9.8 21.4 11.6 18.7 12.3 46.0 7.6 10.9 6.6 13.3 16.9 9.0 7.6 8.7 20.2 3.1 18.2 15.6 13.0 20.0 SERINC5 "C5orf12, TPO1" ENSG00000164300 "Serine incorporator 5" Q86VE9 5 80111651-80256048 "Predicted membrane proteins, Transporters" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity, Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 223.2;Oligodendrocytes: 222.5;Urothelial cells: 254.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 56.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037898, HPA037899" Supported Supported "Vesicles,Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cytosol" "Vesicles, Centrosome" "HPA037898: AB_10673649, HPA037899: AB_2675727" "unprognostic (2.95e-1)" "unprognostic (1.80e-1)" "unprognostic (4.98e-3)" "unprognostic (1.08e-2)" "unprognostic (5.05e-2)" "unprognostic (1.19e-2)" "unprognostic (1.80e-2)" "unprognostic (8.00e-2)" "unprognostic (2.10e-1)" "unprognostic (2.68e-2)" "unprognostic (7.71e-2)" "unprognostic (1.62e-1)" "unprognostic (1.40e-2)" "unprognostic (4.81e-2)" "unprognostic (8.09e-2)" "unprognostic (4.93e-2)" "unprognostic (9.17e-2)" 12.9 34.8 19.2 9.8 31.0 6.3 11.8 27.2 20.7 16.4 17.4 28.3 9.2 9.2 21.1 17.6 16.2 14.2 5.3 18.0 22.7 6.2 45.4 14.1 8.2 26.5 27.6 15.1 7.6 7.1 4.1 16.5 26.8 33.7 29.4 16.3 13.3 7.0 2.7 19.1 9.7 7.6 22.2 4.8 16.6 29.2 28.0 7.9 5.8 2.9 11.4 17.8 11.3 44.4 11.3 19.7 6.6 4.2 8.9 9.5 19.6 9.0 6.0 3.9 4.0 40.0 56.7 1.7 9.0 11.7 9.2 31.7 8.9 23.9 5.6 1.6 4.8 1.4 2.2 21.7 3.3 1.3 4.1 10.8 13.1 10.2 26.0 11.0 7.3 54.0 3.6 9.4 10.4 19.4 22.8 5.5 9.3 15.8 6.8 26.9 5.8 3.0 11.5 54.4 0.4 6.3 8.0 18.5 35.4 33.5 8.2 6.9 8.0 11.3 3.2 11.6 11.3 7.1 3.5 28.1 21.0 3.9 46.9 10.4 9.1 6.7 2.1 4.9 1.6 0.8 18.7 5.7 5.8 1.1 23.3 14.1 5.2 0.6 1.5 1.4 6.6 7.5 19.2 31.0 27.2 20.7 18.0 22.7 26.5 27.6 26.8 22.2 28.0 44.4 48.5 60.9 30.2 46.0 10.5 6.4 56.8 5.6 19.9 3.6 27.7 14.1 8.2 31.5 18.3 16.5 0.0 16.1 12.9 127.4 9.8 26.5 1.7 82.0 29.6 24.5 60.1 24.8 20.9 19.5 25.7 24.9 40.2 157.0 8.2 27.6 35.3 82.7 21.8 3.3 78.3 60.0 4.1 29.2 27.8 7.6 18.3 38.4 5.4 66.5 44.8 65.1 1.0 223.2 222.5 35.4 56.4 39.9 8.7 148.2 27.7 5.1 4.3 5.3 32.9 7.5 17.4 3.1 12.8 44.4 9.8 129.2 37.7 15.2 85.9 254.2 SERPINA5 "PAI3, PCI, PLANH3, PROCI" ENSG00000188488 "Serpin family A member 5" P05154 14 94561442-94593118 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Fertilization, Lipid transport, Transport" "Heparin-binding, Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 484.5;liver: 785.6;testis: 432.4" "Cell type enhanced" "Detected in many" "Cholangiocytes: 400.4;Endometrial ciliated cells: 175.2;Glandular and luminal cells: 345.3;Hepatocytes: 198.2;Late spermatids: 277.8;Peritubular cells: 144.4" "Cancer enhanced" "Detected in many" "liver cancer: 121.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 15 "Hep G2: 261.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA078846 Enhanced "Secreted to blood" NA NA 2100000000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 44: Endometrium - Transcription" "HPA078846: " "unprognostic (5.94e-3)" "unprognostic (2.64e-4)" "unprognostic (1.13e-1)" "prognostic favorable (7.72e-4)" "unprognostic (3.34e-3)" "unprognostic (6.10e-3)" "unprognostic (3.94e-2)" "unprognostic (1.39e-3)" "unprognostic (5.36e-1)" "unprognostic (1.50e-1)" "unprognostic (6.16e-2)" "unprognostic (1.87e-2)" "unprognostic (8.39e-3)" "unprognostic (3.38e-3)" "unprognostic (9.92e-2)" "unprognostic (8.08e-2)" "unprognostic (3.23e-1)" 5.1 484.5 1.8 3.3 2.4 0.0 19.6 2.2 1.7 29.6 3.0 5.3 5.5 31.8 1.2 0.8 26.3 160.5 19.0 1.6 7.2 151.4 785.6 1.0 3.6 3.5 3.8 30.1 173.9 0.2 3.2 0.1 5.3 6.8 1.9 14.0 9.4 153.3 46.4 3.3 3.6 2.1 1.7 112.2 12.1 432.4 2.8 0.9 4.1 152.6 4.7 2.3 4.0 3.7 0.8 0.1 2.7 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 12.0 12.2 0.0 8.3 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 261.3 0.3 0.4 0.0 1.7 0.3 0.1 0.0 2.3 4.9 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.7 0.2 0.0 0.1 0.5 0.2 3.9 0.1 0.4 17.4 0.2 0.1 7.9 0.9 0.1 0.0 0.5 0.0 0.6 0.4 1.5 0.2 0.1 0.2 0.0 0.1 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 2.4 2.2 1.7 1.6 7.2 3.5 3.8 5.3 1.7 2.8 3.7 0.9 0.0 0.0 0.0 0.1 0.8 0.0 0.1 0.0 0.2 18.9 14.1 0.8 400.4 0.1 33.1 2.1 0.0 0.1 0.0 64.6 103.2 78.7 175.2 19.7 40.3 0.0 2.7 0.0 122.2 0.0 18.2 0.5 345.3 0.0 78.2 2.5 198.2 0.0 8.4 0.0 0.0 0.0 3.2 0.7 277.8 57.2 1.9 0.0 0.0 0.6 5.4 0.0 0.0 0.2 18.3 0.0 144.4 0.0 0.1 0.0 7.5 0.0 1.4 6.6 11.6 1.5 11.1 2.9 0.0 0.6 0.3 1.8 58.7 0.0 0.1 SESN1 "PA26, SEST1" ENSG00000080546 "Sestrin 1" Q9Y6P5 6 108986437-109094819 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 137.2;Excitatory neurons: 134.9;Inhibitory neurons: 127.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "B-cells: 48.0;NK-cells: 58.9;T-cells: 74.6" "Cell line enhanced" "Detected in all" "BEWO: 80.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073659 Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 28: BEWO - Transcription regulation" "Cluster 4: Macrophages - Innate immune response" "Nucleoli fibrillar center" Nucleoplasm "HPA073659: AB_2686622" "unprognostic (2.22e-1)" "unprognostic (5.97e-2)" "unprognostic (1.02e-1)" "unprognostic (3.52e-2)" "unprognostic (1.17e-1)" "prognostic favorable (6.47e-5)" "unprognostic (2.68e-1)" "unprognostic (6.91e-2)" "unprognostic (1.01e-1)" "unprognostic (8.33e-2)" "unprognostic (1.83e-3)" "prognostic favorable (2.07e-4)" "unprognostic (3.54e-2)" "unprognostic (1.65e-1)" "unprognostic (1.08e-1)" "unprognostic (5.72e-2)" "unprognostic (7.95e-2)" 30.7 26.6 29.1 23.2 30.7 50.2 42.3 29.8 35.9 29.9 29.8 31.6 20.2 31.7 26.6 22.7 32.5 18.5 36.2 31.1 29.4 16.7 29.2 25.6 33.8 27.9 27.9 62.6 31.6 50.3 25.8 53.4 28.7 25.1 23.9 25.0 18.3 23.6 151.2 43.1 38.1 32.9 28.7 37.0 31.0 42.0 29.9 21.9 32.1 140.0 33.8 28.3 28.2 30.8 3.5 5.7 25.7 12.2 32.1 40.6 80.5 13.8 15.7 4.7 9.0 10.9 3.6 29.3 11.4 10.2 3.7 4.1 7.0 27.6 5.8 2.6 34.7 13.0 6.9 40.9 19.7 5.1 12.7 44.2 43.0 8.5 13.7 20.5 24.7 8.3 9.7 20.5 23.3 6.9 11.3 16.4 10.6 5.7 3.6 9.0 7.3 13.7 10.1 17.4 6.3 12.7 7.5 4.7 5.7 41.3 4.5 33.5 15.3 3.6 7.1 3.3 4.5 20.5 12.5 12.0 7.9 12.8 7.9 11.9 2.7 3.4 34.4 6.3 74.6 13.3 32.4 27.3 2.7 48.0 39.6 20.8 10.0 58.9 8.7 5.4 15.1 20.3 29.1 30.7 29.8 35.9 31.1 29.4 27.9 27.9 28.7 28.7 29.9 30.8 13.9 64.1 22.4 79.0 37.3 6.5 4.9 7.4 25.0 23.8 14.2 14.5 30.0 17.2 15.2 14.7 45.9 57.8 22.9 12.7 9.8 4.3 137.2 10.3 15.2 9.8 15.5 24.2 134.9 5.3 13.7 21.9 28.5 8.2 3.8 17.4 10.8 14.7 44.9 26.9 127.7 10.0 2.0 43.1 11.3 104.8 34.5 56.5 16.0 71.2 9.4 39.1 25.7 64.3 119.1 3.1 11.9 35.3 26.2 9.4 7.8 9.3 26.4 44.3 26.3 43.9 15.9 18.4 16.2 25.4 8.4 44.6 41.8 102.9 13.6 4.3 SETD4 "C21orf18, C21orf27" ENSG00000185917 "SET domain containing 4" Q9NVD3 21 36034541-36079389 "Predicted intracellular proteins" "Inflammatory response" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 54.3;Spermatocytes: 63.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA024073, HPA035405" Approved Approved "Nuclear speckles" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 27: Brain & Skin - Unknown function" "Cluster 16: U-266 - Nucleosome" "Cluster 66: Spermatocytes - Spermatogenesis" "Nuclear speckles" "HPA024073: AB_1856755, HPA035405: AB_2674612" "unprognostic (4.23e-1)" "unprognostic (5.67e-2)" "unprognostic (6.98e-2)" "unprognostic (5.73e-2)" "unprognostic (1.98e-1)" "unprognostic (8.05e-3)" "unprognostic (7.86e-2)" "unprognostic (2.13e-3)" "unprognostic (2.17e-2)" "unprognostic (5.81e-2)" "unprognostic (1.33e-1)" "unprognostic (4.60e-3)" "unprognostic (1.15e-3)" "unprognostic (1.99e-1)" "unprognostic (8.09e-3)" "unprognostic (3.30e-2)" "unprognostic (1.28e-2)" 8.8 9.3 9.1 6.9 9.9 8.4 9.1 9.4 10.4 10.2 15.8 9.5 11.4 9.7 11.1 10.9 10.8 7.8 10.1 9.4 10.5 9.7 7.2 8.4 8.7 9.0 8.3 9.7 7.8 10.0 8.9 9.0 9.5 10.2 9.4 9.6 10.0 7.9 9.8 13.6 9.3 10.9 8.4 8.5 9.9 23.1 9.9 11.1 10.1 8.8 10.9 9.9 10.7 12.1 13.3 9.2 13.6 17.3 6.5 7.9 21.9 17.1 15.0 17.3 11.5 19.2 11.5 7.1 11.9 7.8 13.3 9.7 10.3 10.2 15.0 12.7 12.4 19.2 16.2 12.6 15.9 18.3 10.7 8.3 17.2 11.7 15.0 9.8 13.1 9.6 25.5 12.7 10.7 14.3 12.3 26.3 28.2 11.3 11.6 18.2 10.0 17.3 18.9 9.3 11.2 17.9 17.4 18.5 17.6 11.7 16.3 15.2 11.0 15.0 5.6 9.4 15.9 20.3 31.7 11.2 15.6 24.9 13.2 5.9 12.5 11.3 8.1 10.0 9.0 16.2 10.3 8.8 14.6 13.2 7.3 8.6 9.5 11.0 10.2 15.6 13.0 7.7 9.1 9.9 9.4 10.4 9.4 10.5 9.0 8.3 9.5 8.4 9.9 12.1 9.7 9.6 7.0 11.1 10.8 12.1 11.3 18.6 15.4 13.3 9.0 8.9 9.2 7.2 13.7 9.2 31.3 16.3 13.4 7.9 5.9 12.7 54.3 16.8 10.9 9.3 3.6 7.2 17.4 8.2 9.6 10.4 8.6 8.7 11.4 17.0 7.5 5.5 10.6 3.3 19.2 13.4 26.4 6.9 5.1 10.4 9.6 5.0 10.6 4.7 8.0 7.6 14.4 19.6 19.8 10.0 9.4 10.1 6.2 11.2 20.7 10.3 23.8 21.0 6.6 8.9 9.0 63.1 20.8 13.2 9.1 9.4 8.1 14.8 11.3 11.3 SETD7 "KIAA1717, KMT7, SET7, SET7/9, Set9" ENSG00000145391 "SET domain containing 7, histone lysine methyltransferase" Q8WTS6 4 139495941-139606699 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058111 Enhanced Enhanced "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoli, Nucleoli rim" "Mitotic chromosome" "HPA058111: AB_2683607" "prognostic unfavorable (8.28e-4)" "unprognostic (7.07e-2)" "unprognostic (4.04e-1)" "unprognostic (2.07e-1)" "unprognostic (2.92e-1)" "unprognostic (4.82e-2)" "unprognostic (1.48e-2)" "unprognostic (2.04e-1)" "unprognostic (1.71e-2)" "unprognostic (9.10e-2)" "unprognostic (6.44e-2)" "unprognostic (7.75e-2)" "unprognostic (1.37e-1)" "unprognostic (6.16e-3)" "unprognostic (1.17e-1)" "unprognostic (6.92e-2)" "unprognostic (6.56e-3)" 44.7 18.5 17.8 15.1 17.7 9.7 27.3 19.3 17.3 40.5 21.2 23.5 7.3 33.0 12.6 28.1 18.8 26.7 41.0 16.6 19.4 10.1 50.1 19.2 11.7 25.0 20.3 19.6 21.9 34.7 8.8 19.1 24.7 35.1 15.3 11.5 16.2 20.6 106.6 22.7 12.1 34.8 24.6 17.0 20.1 14.4 24.5 10.1 14.1 73.7 15.9 23.4 18.2 29.2 28.4 37.2 13.0 7.8 77.1 65.9 29.6 65.7 67.3 32.4 27.1 22.7 37.2 68.0 25.5 110.5 22.4 13.9 44.3 51.3 52.4 32.8 33.0 8.9 45.5 0.8 38.4 31.9 12.9 57.7 58.6 52.1 54.6 41.2 41.7 27.8 5.5 96.1 42.3 46.8 21.0 4.6 6.4 40.8 23.9 19.7 48.4 37.3 31.5 25.3 55.3 18.5 44.7 63.5 15.3 12.6 25.3 28.0 68.8 57.1 40.7 68.6 55.2 89.6 86.8 42.2 65.9 31.1 28.0 0.5 3.9 0.2 0.3 2.0 2.7 1.0 1.1 1.1 4.4 1.2 0.4 0.2 0.9 0.2 3.2 2.1 3.7 1.2 17.8 17.7 19.3 17.3 16.6 19.4 25.0 20.3 24.7 24.6 24.5 29.2 28.7 6.4 18.8 17.3 8.9 17.2 14.5 14.1 12.5 5.4 24.0 14.7 43.1 20.0 15.0 9.2 12.5 26.2 4.2 4.1 0.0 22.7 1.3 3.5 35.9 29.4 1.2 3.6 21.1 21.2 16.7 39.8 16.8 7.5 2.5 2.9 37.1 70.6 20.4 8.4 42.4 13.6 18.3 31.0 20.9 4.3 23.0 19.5 10.6 19.7 19.0 15.0 0.0 36.2 29.2 22.4 4.1 28.2 13.2 38.4 1.3 4.5 14.0 12.9 19.7 35.2 23.3 3.7 2.7 17.9 22.0 46.1 9.8 9.5 11.7 20.4 SFR1 "bA373N18.1, C10orf78, FLJ41960, MEI5, MEIR5" ENSG00000156384 "SWI5 dependent homologous recombination repair protein 1" Q86XK3 10 104122058-104126385 "Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 7 "Spermatocytes: 233.6;Spermatogonia: 76.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA039617 Uncertain NA NA "Cluster 44: Non-specific - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA039617: AB_10805482" "unprognostic (2.79e-2)" "unprognostic (2.58e-3)" "unprognostic (1.94e-2)" "unprognostic (3.78e-1)" "unprognostic (8.54e-2)" "unprognostic (4.42e-3)" "prognostic unfavorable (2.59e-5)" "unprognostic (6.20e-2)" "unprognostic (9.39e-2)" "unprognostic (5.19e-2)" "unprognostic (8.88e-3)" "unprognostic (2.21e-2)" "prognostic unfavorable (2.23e-4)" "unprognostic (2.86e-2)" "unprognostic (4.66e-2)" "unprognostic (8.44e-2)" "unprognostic (2.24e-2)" 4.8 4.4 5.6 7.2 8.2 10.0 6.6 7.1 7.9 3.8 6.1 5.2 4.7 5.4 7.3 4.9 5.4 4.9 7.6 5.5 5.9 4.9 3.1 6.3 9.0 7.9 7.0 8.9 5.9 3.5 2.9 3.9 7.6 3.9 6.4 4.2 4.0 3.4 4.1 4.4 6.1 5.6 6.5 6.3 5.5 18.3 7.0 11.7 7.3 5.3 7.6 5.4 3.2 11.2 22.2 12.4 13.1 5.5 5.0 8.9 7.7 11.6 14.0 7.4 9.7 5.5 45.7 17.7 10.9 3.1 15.5 18.4 6.6 15.8 11.8 15.6 7.5 13.3 5.4 7.0 9.3 15.7 8.5 4.9 5.8 14.8 20.3 9.9 15.3 18.2 8.6 12.5 9.3 6.8 16.0 28.3 6.2 13.0 9.0 19.8 19.1 9.4 16.0 5.9 7.2 7.4 7.4 4.0 9.9 10.9 10.1 6.9 7.1 4.2 15.2 12.9 18.8 14.9 19.2 18.0 12.2 16.6 5.7 23.6 16.8 10.4 14.3 16.5 14.6 16.6 14.9 15.2 11.9 19.2 21.7 18.3 5.4 12.8 12.1 10.3 13.5 14.9 5.6 8.2 7.1 7.9 5.5 5.9 7.9 7.0 7.6 6.5 7.0 11.2 12.1 3.2 11.8 1.3 9.9 21.5 14.6 10.4 2.8 3.5 6.8 7.0 8.5 8.6 13.8 1.8 0.0 9.7 9.8 4.7 17.6 12.1 20.0 8.0 6.3 13.7 3.0 21.8 1.3 12.3 13.7 10.2 2.6 7.8 12.0 8.1 18.2 1.9 17.6 5.0 2.6 6.3 18.3 16.3 12.4 11.3 9.6 12.5 3.6 4.7 17.8 9.6 15.5 1.0 14.0 19.1 5.1 6.0 4.5 5.1 5.7 10.1 5.3 4.9 0.0 13.0 9.0 233.6 76.7 5.5 7.4 3.8 10.4 5.6 7.2 8.7 SFXN4 SLC56A4 ENSG00000183605 "Sideroflexin 4" Q6P4A7 10 119140767-119165714 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018028, HPA020872" Approved Approved Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Mitochondria" Vesicles "HPA018028: AB_1856792, HPA020872: AB_1856793" "unprognostic (8.13e-2)" "unprognostic (6.11e-2)" "unprognostic (3.61e-1)" "unprognostic (1.12e-1)" "unprognostic (1.27e-2)" "unprognostic (9.49e-2)" "unprognostic (1.59e-2)" "unprognostic (1.72e-1)" "unprognostic (6.84e-2)" "unprognostic (4.56e-2)" "unprognostic (8.58e-2)" "unprognostic (2.94e-2)" "unprognostic (1.70e-3)" "unprognostic (4.22e-3)" "unprognostic (1.43e-1)" "unprognostic (6.21e-3)" "unprognostic (3.07e-3)" 13.3 35.9 9.9 10.1 12.5 16.4 14.1 12.8 13.6 14.2 17.0 21.9 20.4 11.1 13.5 19.1 14.3 8.6 33.1 10.2 12.4 24.5 36.4 8.5 14.4 11.3 12.5 16.0 33.7 23.1 21.5 8.8 11.6 18.8 22.7 5.7 27.8 13.2 51.4 11.5 17.3 12.2 10.6 20.9 17.3 11.9 11.3 11.0 24.7 59.3 17.8 16.4 13.8 12.5 26.2 27.6 8.7 41.8 10.4 19.7 33.0 16.3 19.8 21.0 21.8 45.9 43.2 62.6 15.6 14.9 22.4 48.2 57.5 36.3 24.3 33.1 65.7 28.7 18.4 47.3 37.1 49.7 28.8 21.1 34.4 22.0 63.8 19.5 25.0 46.5 45.2 17.5 13.6 29.6 53.8 60.4 11.8 50.2 32.5 51.7 27.1 49.0 24.3 17.3 25.2 13.9 10.8 42.2 61.9 11.1 26.0 28.4 11.5 10.6 21.9 19.8 37.6 42.6 53.0 56.3 16.2 72.6 7.2 2.5 18.1 1.9 6.5 19.5 10.8 12.5 7.9 7.1 21.2 7.0 12.1 9.8 2.2 7.3 15.9 10.6 6.0 11.1 9.9 12.5 12.8 13.6 10.2 12.4 11.3 12.5 11.6 10.6 11.3 12.5 8.0 6.4 5.6 29.0 16.9 12.0 25.8 39.9 23.3 7.9 17.8 18.2 36.2 12.8 19.1 14.7 2.1 37.6 6.2 13.2 58.7 28.4 27.4 7.6 8.9 8.4 18.0 33.6 22.3 23.8 25.8 12.4 14.3 7.9 5.7 28.5 7.1 31.5 29.2 6.7 29.1 24.7 30.5 17.6 5.0 69.3 8.7 13.1 12.4 8.4 11.3 7.7 10.3 22.1 19.5 17.6 12.1 13.5 31.9 28.0 29.8 65.6 13.5 11.3 6.6 22.3 10.6 27.7 15.2 26.9 9.1 21.9 9.2 44.5 45.8 20.5 SGCA "A2, adhalin, ADL, DMDA2, LGMD2D, SCARMD1" ENSG00000108823 "Sarcoglycan alpha" Q16586 17 50164214-50175928 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "heart muscle: 155.6;skeletal muscle: 522.4;tongue: 237.0" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 128.4;Early spermatids: 162.6;Late spermatids: 705.4;Skeletal myocytes: 195.2" "Cancer enhanced" "Detected in many" "prostate cancer: 4.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "intermediate monocyte: 1.4;memory B-cell: 3.3;myeloid DC: 2.2;naive B-cell: 3.3;non-classical monocyte: 1.8" "Group enriched" "Detected in many" 15 "B-cells: 3.3;dendritic cells: 2.2;monocytes: 1.8" "Cell line enriched" "Detected in some" 16 "LHCN-M2: 78.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA007537 Uncertain "Intracellular and membrane" NA NA "Cluster 37: B-cells - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 31: Spermatids - Spermatogenesis" "HPA007537: AB_1079944" "unprognostic (1.34e-1)" "unprognostic (2.30e-2)" "unprognostic (1.89e-3)" "unprognostic (1.25e-1)" "unprognostic (9.87e-2)" "unprognostic (2.43e-2)" "unprognostic (9.25e-2)" "unprognostic (1.22e-2)" "unprognostic (1.15e-1)" "unprognostic (1.91e-1)" "unprognostic (7.01e-2)" "unprognostic (2.57e-1)" "unprognostic (2.07e-3)" "unprognostic (4.96e-2)" "unprognostic (2.16e-1)" "unprognostic (2.95e-1)" "unprognostic (1.15e-2)" 12.2 1.5 1.8 7.3 2.9 0.0 4.3 3.5 2.2 10.1 1.0 53.7 5.3 36.9 1.6 22.8 18.1 11.9 155.6 1.4 1.5 2.7 4.8 29.7 0.5 1.6 1.5 5.1 1.3 0.8 0.9 6.7 1.8 26.0 3.2 0.1 8.7 27.1 522.4 12.4 14.8 23.0 1.1 3.4 24.1 1.7 1.7 2.3 3.4 237.0 0.4 46.5 11.6 4.7 0.0 0.0 0.0 0.0 0.0 0.5 0.9 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 78.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 4.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.8 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.5 0.0 0.4 0.1 0.0 1.4 0.0 3.3 0.0 0.0 2.2 3.3 0.0 0.1 0.0 0.0 1.8 0.0 0.0 0.4 1.8 2.9 3.5 2.2 1.4 1.5 1.6 1.5 1.8 1.1 1.7 4.7 1.1 0.0 0.0 0.0 1.3 8.7 0.5 0.4 0.0 0.6 0.1 0.5 128.4 0.0 0.3 0.0 0.0 0.5 1.4 0.0 0.0 0.6 162.6 0.0 0.2 4.6 0.0 0.0 0.0 5.8 0.1 30.4 0.5 0.0 0.0 0.0 2.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 16.5 705.4 3.1 0.8 8.8 1.9 1.9 0.0 0.0 0.0 0.1 4.1 0.0 3.8 0.1 0.6 0.0 2.1 0.0 0.0 13.1 195.2 48.2 2.3 1.9 0.1 9.9 0.3 0.9 0.0 0.0 0.2 SGF29 "CCDC101, FLJ32446, TDRD29" ENSG00000176476 "SAGA complex associated factor 29" Q96ES7 16 28553915-28591790 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 7 "Early spermatids: 222.2;Late spermatids: 384.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052590, HPA053608" Enhanced Approved Nucleoplasm,Nucleoli Yes No "Cluster 26: Non-specific - Mitochondria" "Cluster 23: Testis - Cell cycle regulation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 34: Spermatids - Unknown function" Nucleoli Nucleoplasm "HPA052590: AB_2681875, HPA053608: AB_2682205" "unprognostic (1.38e-2)" "prognostic favorable (4.77e-4)" "unprognostic (1.73e-1)" "unprognostic (2.46e-3)" "unprognostic (2.80e-2)" "unprognostic (7.27e-3)" "unprognostic (1.48e-1)" "prognostic favorable (3.37e-4)" "unprognostic (1.98e-1)" "unprognostic (1.41e-1)" "prognostic favorable (2.99e-4)" "unprognostic (2.96e-1)" "unprognostic (1.35e-2)" "unprognostic (1.66e-1)" "unprognostic (2.19e-1)" "unprognostic (1.76e-1)" "unprognostic (5.42e-3)" 16.8 16.1 13.6 11.2 15.6 12.4 16.5 16.7 14.6 26.8 13.8 28.0 12.8 29.1 9.5 12.0 27.6 9.1 15.3 13.4 14.9 11.1 19.9 14.0 16.9 15.2 14.4 33.3 25.6 10.7 10.3 7.1 15.4 16.4 7.2 7.8 16.6 16.7 51.1 16.0 18.8 12.0 14.9 16.2 19.8 43.0 14.6 14.1 17.6 19.8 10.2 23.5 16.4 16.8 13.1 21.3 16.3 10.5 10.6 10.9 29.5 8.5 9.6 21.7 20.2 24.6 11.5 39.1 21.1 6.7 13.2 15.0 12.4 15.4 6.1 12.8 24.0 24.3 12.9 33.7 27.1 22.1 26.1 11.5 20.0 13.1 13.2 11.7 8.3 24.5 20.8 19.4 7.9 43.4 25.5 43.2 22.7 9.6 20.5 38.9 10.6 34.2 11.3 19.5 26.3 12.2 13.3 25.3 15.0 5.8 20.7 18.4 5.9 15.4 12.9 9.2 15.3 22.4 35.7 22.7 10.9 36.9 12.5 20.6 47.0 50.0 53.6 41.8 65.2 57.9 74.2 65.8 47.6 65.9 84.1 66.3 13.4 55.1 33.7 71.4 78.3 58.7 13.6 15.6 16.7 14.6 13.4 14.9 15.2 14.4 15.4 14.9 14.6 16.8 11.2 16.0 16.7 0.0 20.0 0.0 18.1 0.0 32.5 5.5 12.5 21.1 0.0 12.8 7.4 18.4 14.6 17.3 27.1 7.9 9.8 12.6 222.2 8.5 10.1 8.7 3.6 17.1 0.0 12.9 11.8 12.7 10.2 7.7 6.3 16.9 11.0 17.3 14.2 0.0 0.0 8.8 0.0 12.9 0.0 384.4 30.7 13.5 0.0 0.0 17.1 11.8 22.6 0.0 0.0 10.1 15.7 21.8 16.7 9.5 40.1 23.7 6.6 14.1 19.7 18.3 13.0 10.5 30.9 17.0 0.0 21.1 21.0 14.8 11.9 12.0 SH2B1 "FLJ30542, SH2B" ENSG00000178188 "SH2B adaptor protein 1" Q9NRF2 16 28846600-28874212 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060663, HPA076175" Enhanced Approved "Nucleoplasm,Centriolar satellite,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 35: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Centriolar satellite, Cytosol" "HPA060663: , HPA076175: AB_2686782" "unprognostic (3.60e-2)" "unprognostic (1.94e-2)" "unprognostic (8.94e-2)" "unprognostic (2.27e-1)" "unprognostic (3.27e-1)" "unprognostic (3.27e-3)" "unprognostic (6.10e-2)" "prognostic favorable (9.40e-4)" "unprognostic (3.94e-2)" "unprognostic (1.18e-1)" "prognostic favorable (4.38e-4)" "unprognostic (1.39e-2)" "prognostic favorable (2.81e-6)" "unprognostic (1.53e-1)" "unprognostic (1.05e-1)" "unprognostic (1.46e-1)" "prognostic favorable (1.60e-4)" 36.7 57.4 53.8 32.8 54.8 38.6 39.5 58.6 75.2 58.5 42.8 59.7 46.4 54.9 20.9 39.4 54.3 30.0 52.9 53.6 47.0 62.1 44.6 35.6 39.2 49.0 47.8 69.4 53.4 55.2 70.1 20.9 48.8 57.7 28.5 29.1 49.2 36.8 58.2 40.6 57.1 24.8 38.1 63.4 51.9 48.8 51.4 36.5 71.6 50.6 25.2 47.1 44.9 58.4 29.9 43.2 32.3 41.7 33.3 28.2 26.9 30.4 17.1 23.4 25.3 29.0 49.2 27.4 41.7 24.5 20.2 46.4 21.3 33.9 13.2 35.9 27.6 24.4 111.3 45.0 25.2 24.8 22.4 39.4 27.2 32.9 13.3 40.0 27.4 27.8 39.8 39.1 31.3 40.3 37.2 36.4 41.9 15.6 17.3 62.3 19.4 46.1 27.2 22.2 36.9 49.7 14.7 42.4 22.3 19.1 33.4 26.5 38.8 26.9 22.5 23.8 23.6 74.0 40.2 30.9 41.8 43.0 27.5 3.3 1.4 0.6 2.0 1.1 1.9 1.6 1.6 1.4 1.1 1.7 1.2 1.1 2.1 0.6 1.1 1.9 1.8 0.9 53.8 54.8 58.6 75.2 53.6 47.0 49.0 47.8 48.8 38.1 51.4 58.4 14.1 6.4 13.7 37.5 13.9 10.8 15.9 15.4 22.8 26.7 17.4 13.8 18.4 17.2 15.7 22.0 33.3 16.6 12.8 31.1 15.6 9.5 2.2 11.0 11.0 12.7 27.6 7.8 25.6 12.9 8.2 15.0 19.4 11.4 6.3 20.1 13.9 8.9 12.2 28.6 26.8 24.7 14.2 8.7 7.2 5.4 22.1 10.8 3.6 13.1 10.7 18.1 22.6 21.6 19.0 12.8 24.9 23.7 10.5 10.4 26.3 10.2 12.5 28.9 26.3 12.9 15.7 9.9 12.8 17.4 11.1 13.7 15.3 20.4 28.4 12.3 SH2B3 "IDDM20, LNK" ENSG00000111252 "SH2B adaptor protein 3" Q9UQQ2 12 111405923-111451623 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 60.7" "Cell type enhanced" "Detected in many" "Kupffer cells: 113.6;Langerhans cells: 130.9;Macrophages: 84.1;monocytes: 67.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 122.2;hTEC/SVTERT24-B: 140.7;U-87 MG: 211.6;WM-115: 165.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005483 Approved Approved Nucleoplasm NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "HPA005483: AB_1079260" "unprognostic (2.77e-1)" "unprognostic (1.74e-1)" "unprognostic (1.20e-1)" "unprognostic (1.12e-1)" "unprognostic (1.18e-1)" "unprognostic (9.09e-2)" "unprognostic (1.23e-1)" "unprognostic (2.42e-1)" "unprognostic (1.18e-1)" "unprognostic (4.65e-2)" "unprognostic (8.17e-3)" "unprognostic (9.08e-2)" "prognostic unfavorable (6.20e-4)" "unprognostic (2.86e-1)" "unprognostic (3.89e-3)" "unprognostic (1.11e-1)" "unprognostic (2.24e-2)" 22.2 10.9 10.2 21.9 6.8 60.7 13.3 3.5 9.3 8.6 8.5 11.4 8.1 8.5 3.3 7.7 8.1 18.6 23.4 5.8 6.5 14.3 17.4 20.5 21.0 12.0 7.3 5.5 10.2 5.8 8.0 24.4 10.0 7.3 13.5 3.7 5.3 5.9 9.6 4.1 12.5 13.6 10.1 37.1 7.1 9.5 12.1 10.5 11.1 9.5 15.8 15.7 6.0 14.7 9.2 5.5 7.0 7.3 23.9 35.5 4.8 29.2 79.5 21.9 23.3 8.4 5.2 15.6 20.3 44.6 73.6 1.7 5.5 16.9 35.2 13.3 2.7 53.2 2.6 6.2 23.3 23.5 122.2 21.2 3.8 140.7 12.7 48.4 119.1 12.8 38.9 6.1 80.2 3.2 9.7 46.7 11.0 2.4 21.0 9.5 15.9 10.2 10.5 3.7 4.6 4.9 5.4 0.6 42.2 6.2 3.5 33.4 93.0 20.0 11.3 17.4 48.1 13.9 15.8 17.6 211.6 16.6 165.3 0.9 3.5 1.2 1.2 8.4 1.0 1.5 1.1 1.3 4.8 0.5 0.7 1.0 3.0 1.8 6.6 4.9 0.4 1.8 10.2 6.8 3.5 9.3 5.8 6.5 12.0 7.3 10.0 10.1 12.1 14.7 26.8 3.2 22.0 2.6 26.2 6.8 1.5 4.2 1.2 4.6 4.3 3.8 17.5 4.3 4.3 1.8 2.1 0.4 40.6 15.0 1.9 3.6 13.1 1.0 2.2 39.2 3.5 11.2 11.0 9.0 1.4 8.1 0.5 1.2 38.6 0.8 46.1 11.1 40.4 3.3 7.3 3.0 6.1 113.6 130.9 5.3 2.8 84.1 16.0 38.4 67.1 1.1 18.6 11.1 9.0 7.2 5.9 4.1 4.9 3.0 0.8 1.5 3.5 3.4 0.0 4.0 12.7 12.5 4.5 0.7 4.1 1.0 12.1 4.4 3.2 1.2 SH3BGRL2 ENSG00000198478 "SH3 domain binding glutamate rich protein like 2" Q9UJC5 6 79631329-79703655 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 161.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 156.3;Excitatory neurons: 86.5;Intestinal goblet cells: 87.8" "Cancer enhanced" "Detected in all" "thyroid cancer: 50.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "basophil: 11.1" "Lineage enriched" "Detected in many" 10 "granulocytes: 11.1" "Cell line enhanced" "Detected in many" "CACO-2: 81.6;HEL: 41.8;OE19: 99.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047486 Approved Supported Nucleoplasm NA NA 2000000 "Cluster 34: Basophils - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA047486: AB_2680065" "unprognostic (3.48e-2)" "unprognostic (1.95e-1)" "unprognostic (1.75e-2)" "unprognostic (2.28e-2)" "unprognostic (4.21e-1)" "unprognostic (7.77e-2)" "unprognostic (1.07e-1)" "unprognostic (1.60e-2)" "unprognostic (6.92e-2)" "unprognostic (6.53e-3)" "unprognostic (2.78e-1)" "unprognostic (7.94e-2)" "prognostic favorable (2.24e-4)" "unprognostic (1.60e-1)" "unprognostic (1.51e-1)" "unprognostic (2.11e-2)" "unprognostic (1.33e-1)" 26.4 6.9 18.8 7.5 18.6 1.7 21.6 15.6 27.5 22.3 15.1 50.5 35.2 9.9 24.7 55.1 17.8 23.2 6.8 21.4 21.8 15.7 53.1 12.7 5.5 26.7 22.0 4.1 23.3 31.5 16.6 24.0 28.1 26.2 47.9 26.0 161.7 11.4 4.8 11.3 35.6 15.8 24.1 6.6 68.9 2.1 24.2 4.8 59.1 10.1 10.7 12.7 19.7 22.5 8.5 1.5 7.6 1.6 6.7 5.6 18.0 0.5 5.6 1.9 4.0 81.6 16.3 0.1 11.4 0.5 1.6 3.9 7.0 9.2 6.7 0.0 10.2 41.8 1.8 15.8 2.8 1.7 1.1 3.1 7.3 5.8 3.3 2.7 23.8 0.0 16.8 0.0 0.7 1.3 0.0 0.2 6.5 99.7 2.8 0.0 2.2 0.2 2.0 27.3 20.3 22.3 0.5 2.4 0.6 10.3 0.4 3.5 13.6 5.2 3.4 0.1 4.9 12.0 6.0 0.0 0.9 0.0 1.6 11.1 0.2 0.4 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 1.0 2.2 0.0 0.0 0.1 0.0 8.8 18.8 18.6 15.6 27.5 21.4 21.8 26.7 22.0 28.1 24.1 24.2 22.5 83.2 6.4 24.8 20.9 0.9 2.2 4.6 3.3 2.2 13.5 14.8 9.9 6.1 52.9 21.4 22.0 8.4 40.4 1.7 156.3 0.0 14.8 18.1 14.3 3.7 33.8 12.6 7.4 86.5 13.0 3.7 4.6 81.1 21.0 0.0 2.0 44.6 69.6 4.1 13.5 38.1 87.8 4.1 2.9 2.1 20.3 0.6 21.6 16.0 11.2 4.6 8.6 0.0 33.7 24.9 15.0 76.0 4.5 1.3 19.7 48.7 11.3 24.6 12.2 0.0 3.7 4.7 2.5 1.2 21.5 0.9 52.7 1.0 1.8 67.2 29.9 SH3BP4 ENSG00000130147 "SH3 domain binding protein 4" Q9P0V3 2 234952017-235055714 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 83.5" "Cell type enhanced" "Detected in many" "Prostatic glandular cells: 96.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 2.0;plasmacytoid DC: 3.1" "Lineage enhanced" "Detected in single" "dendritic cells: 3.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037533, HPA037534" Uncertain NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 35: Glandular cells - Unknown function" "HPA037533: AB_10672903, HPA037534: AB_2675528" "unprognostic (2.16e-3)" "unprognostic (1.43e-1)" "unprognostic (2.83e-2)" "unprognostic (1.30e-1)" "unprognostic (1.16e-1)" "unprognostic (5.38e-1)" "unprognostic (2.73e-2)" "unprognostic (1.45e-1)" "unprognostic (2.38e-1)" "unprognostic (3.89e-2)" "unprognostic (1.61e-1)" "unprognostic (4.30e-1)" "prognostic favorable (2.07e-6)" "unprognostic (2.86e-2)" "unprognostic (5.08e-2)" "unprognostic (6.91e-2)" "unprognostic (1.17e-2)" 12.4 9.0 17.8 5.7 21.8 1.1 35.3 21.7 15.9 20.8 20.4 13.8 17.2 12.5 14.5 7.7 17.5 19.0 10.2 14.5 16.2 18.3 26.1 13.2 2.2 21.3 21.1 22.5 61.3 5.8 4.0 18.2 20.5 20.3 13.7 2.4 83.5 16.8 9.5 16.6 11.1 13.6 15.8 5.6 25.6 10.2 19.7 4.7 11.1 9.4 3.8 9.4 7.5 28.1 49.3 30.6 77.7 5.8 33.8 22.4 35.2 70.2 66.6 54.6 48.8 23.5 28.8 0.0 19.0 140.4 126.8 26.1 22.6 47.2 64.8 0.2 10.3 0.0 39.5 64.1 55.8 0.0 0.1 43.9 69.9 76.6 41.4 52.4 58.7 0.1 0.4 0.2 81.4 37.8 0.1 0.2 42.5 56.2 16.8 0.0 16.0 9.3 50.0 9.9 47.9 19.3 15.8 101.4 42.7 55.2 11.9 0.2 47.2 59.8 52.2 47.1 45.7 0.0 0.1 0.2 55.6 0.1 89.2 0.9 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.1 0.0 3.1 0.0 0.1 17.8 21.8 21.7 15.9 14.5 16.2 21.3 21.1 20.5 15.8 19.7 28.1 23.5 3.2 9.1 4.2 1.0 14.8 50.2 15.6 14.2 2.3 37.3 18.0 6.6 18.6 22.5 7.3 6.2 8.7 3.9 6.0 9.8 24.7 3.4 21.4 10.9 22.9 6.6 1.3 0.7 24.8 29.9 11.7 14.8 29.2 1.3 10.0 17.2 26.8 2.1 3.3 1.4 9.1 16.2 1.4 13.1 4.9 8.1 10.9 24.9 20.6 2.6 1.3 0.0 18.1 52.4 39.6 6.3 9.4 0.2 96.9 0.8 1.9 20.7 0.7 0.0 1.9 12.4 0.8 2.8 8.8 11.1 37.1 0.5 5.5 18.0 30.4 SHANK3 "KIAA1650, prosap2, PSAP2, SPANK-2" ENSG00000251322 "SH3 and multiple ankyrin repeat domains 3" 22 50674415-50733298 "Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 73.5" "Cell type enhanced" "Detected in many" "Adipocytes: 195.3;Endothelial cells: 65.0;Hepatic stellate cells: 70.3;Microglial cells: 44.0;Oligodendrocytes: 31.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 33.3;TIME: 37.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003446 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Plasma membrane" "HPA003446: AB_1079958" "unprognostic (3.62e-1)" "unprognostic (1.08e-2)" "prognostic unfavorable (7.40e-4)" "unprognostic (6.02e-2)" "unprognostic (4.17e-1)" "unprognostic (1.72e-3)" "unprognostic (3.41e-2)" "unprognostic (3.13e-1)" "unprognostic (9.67e-2)" "unprognostic (5.62e-2)" "unprognostic (2.09e-2)" "unprognostic (7.52e-2)" "unprognostic (2.47e-2)" "unprognostic (7.81e-2)" "unprognostic (1.19e-1)" "unprognostic (4.89e-2)" "unprognostic (1.41e-1)" 34.9 4.0 38.9 4.9 21.6 1.1 33.5 73.5 54.7 12.8 0.0 7.5 3.4 13.4 2.0 5.2 12.4 5.8 26.2 44.7 14.9 11.9 4.4 20.3 4.2 10.0 15.3 4.3 4.0 3.5 5.2 13.7 2.6 8.3 1.2 0.7 8.2 4.2 23.3 7.1 6.4 5.1 0.0 50.4 5.7 2.2 38.6 1.7 14.8 8.9 1.4 10.7 10.1 16.2 6.6 2.6 6.2 4.8 0.5 1.6 3.2 1.3 0.0 0.4 0.5 1.6 2.4 0.0 4.0 1.0 3.1 1.2 0.9 2.3 0.0 0.0 10.4 8.0 1.8 7.1 1.9 1.8 0.4 2.2 1.8 0.1 0.3 0.1 33.3 1.9 0.2 0.2 0.5 2.6 1.4 0.5 3.2 0.6 2.2 7.5 0.0 1.7 0.4 1.3 2.3 3.0 2.7 0.0 3.1 0.7 0.3 0.7 37.6 0.4 9.3 2.0 0.7 0.3 0.4 0.0 0.0 0.6 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.9 21.6 73.5 54.7 44.7 14.9 10.0 15.3 2.6 0.0 38.6 16.2 195.3 0.0 1.1 4.6 0.5 0.3 0.1 0.5 4.0 1.2 1.3 2.4 27.6 0.0 0.8 0.0 0.0 0.0 0.8 0.1 0.0 0.0 2.9 3.9 2.4 65.0 2.4 0.0 28.3 0.0 0.0 3.3 0.0 1.5 0.0 0.3 70.3 6.5 0.4 0.0 21.7 0.0 2.0 3.1 0.0 0.4 0.0 0.3 0.0 44.0 0.0 1.4 0.0 25.1 31.3 0.1 0.0 0.4 0.0 0.2 0.0 0.9 0.9 0.0 0.0 1.0 3.8 0.2 0.8 1.0 0.3 0.0 0.6 0.7 0.1 0.3 SHCBP1 "FLJ22009, PAL" ENSG00000171241 "SHC binding and spindle associated 1" Q8NEM2 16 46578591-46621379 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 17.4;lymphoid tissue: 10.6" "Cell type enhanced" "Detected in many" "Erythroid cells: 36.2;Extravillous trophoblasts: 28.7;Plasma cells: 38.3;Spermatocytes: 33.7;Spermatogonia: 23.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA048876 Uncertain Approved "Nuclear bodies,Microtubules,Midbody,Mitotic spindle" Yes Yes "Cluster 19: B-cells - Humoral immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear bodies" "Microtubules, Midbody, Mitotic spindle" "HPA048876: AB_2680542" "unprognostic (2.44e-3)" "unprognostic (1.13e-1)" "unprognostic (2.98e-2)" "unprognostic (2.74e-1)" "unprognostic (2.54e-2)" "unprognostic (2.35e-2)" "unprognostic (2.96e-4)" "unprognostic (2.26e-3)" "unprognostic (5.35e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (4.47e-5)" "unprognostic (4.81e-2)" "unprognostic (2.22e-16)" "unprognostic (3.59e-2)" "unprognostic (3.86e-2)" "unprognostic (2.66e-1)" "unprognostic (2.66e-1)" 0.7 0.5 0.5 5.1 0.5 17.4 0.9 1.2 0.6 0.6 0.4 1.9 1.2 0.6 0.6 3.5 0.2 0.6 1.0 0.4 0.2 5.4 0.2 1.0 9.8 0.4 0.3 0.3 0.2 0.2 0.2 2.4 0.4 0.3 2.2 0.2 0.8 0.2 1.5 3.3 1.5 1.7 0.1 4.4 0.9 5.2 0.5 8.8 0.3 0.2 10.6 1.2 1.2 0.7 33.8 30.8 11.9 15.3 3.1 6.2 16.2 60.7 24.6 59.2 26.8 14.6 20.8 28.0 30.2 28.8 26.8 21.0 29.3 21.7 73.8 17.7 17.2 28.2 25.8 30.3 0.1 28.5 35.4 1.2 1.6 45.9 18.1 5.9 33.0 14.9 12.7 28.3 69.7 21.5 24.0 23.7 10.0 17.2 31.6 45.4 89.9 44.8 13.7 9.4 5.0 7.2 46.0 23.7 11.1 11.4 13.0 23.4 16.1 43.9 28.7 43.5 54.0 24.9 36.7 46.7 21.4 31.3 45.8 0.2 0.3 0.6 0.2 0.5 0.0 1.7 0.3 0.1 0.3 1.2 0.0 0.1 0.4 0.1 2.4 0.7 1.2 1.1 0.5 0.5 1.2 0.6 0.4 0.2 0.4 0.3 0.4 0.1 0.5 0.7 0.2 0.0 1.1 1.3 7.1 1.7 0.7 1.2 0.0 0.3 0.6 1.1 1.9 1.5 1.4 0.0 0.0 11.3 0.8 1.9 0.0 0.2 8.4 0.7 1.7 1.7 0.0 36.2 2.1 0.0 28.7 3.7 4.1 1.5 0.0 7.6 1.8 0.3 12.6 0.0 0.7 2.2 2.0 4.5 3.3 2.3 0.6 4.0 1.8 2.8 2.8 0.8 0.0 1.0 0.5 0.1 0.1 0.4 38.3 0.5 0.4 0.1 0.1 0.3 0.0 0.5 6.3 33.7 23.7 3.6 0.6 3.7 2.2 0.8 3.4 1.1 SHISAL1 KIAA1644 ENSG00000138944 "Shisa like 1" Q3SXP7 22 44243665-44312951 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 43.2;endometrium 1: 33.6;smooth muscle: 29.3" "Cell type enriched" "Detected in single" 6 "Endometrial stromal cells: 4.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SiHa: 36.2;U-2197: 80.8;U-87 MG: 46.3;WM-115: 27.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051178 Uncertain Approved Vesicles,Cytosol No No "Cluster 57: Non-specific - Angiogenesis" "Cluster 18: U-2197 - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "Vesicles, Cytosol" "HPA051178: AB_2681374" "unprognostic (4.07e-3)" "unprognostic (9.01e-2)" "unprognostic (1.83e-1)" "unprognostic (1.14e-1)" "unprognostic (6.54e-2)" "unprognostic (1.22e-1)" "unprognostic (7.79e-2)" "unprognostic (2.64e-2)" "unprognostic (8.10e-3)" "unprognostic (1.93e-3)" "unprognostic (1.33e-1)" "unprognostic (1.99e-1)" "unprognostic (1.51e-7)" "unprognostic (1.48e-2)" "unprognostic (2.41e-1)" "unprognostic (1.99e-4)" "unprognostic (1.10e-4)" 1.0 1.8 18.6 1.2 17.2 0.0 0.2 0.0 21.4 16.6 0.0 18.7 1.9 33.6 0.4 1.6 4.5 3.1 0.9 18.0 15.3 0.5 0.1 0.3 0.4 10.8 17.8 1.0 0.8 0.1 2.6 0.5 2.4 3.7 2.0 5.6 0.3 11.0 0.0 0.7 2.4 29.3 0.3 0.1 1.6 1.1 43.2 2.6 0.4 0.1 0.7 11.9 5.2 2.8 0.0 0.3 3.5 1.2 0.0 0.0 0.0 1.0 2.3 2.4 1.4 0.0 0.0 0.0 0.0 2.3 14.5 0.0 5.0 0.3 0.3 0.0 2.3 0.0 13.0 0.0 0.0 0.0 0.0 0.0 0.4 4.5 1.8 11.2 0.5 0.0 0.0 0.1 0.1 0.0 0.4 0.0 3.3 0.0 0.8 0.0 0.0 0.1 0.0 0.0 12.9 0.0 36.2 0.1 0.2 0.4 0.0 0.3 0.1 13.1 2.0 80.8 0.5 0.0 0.0 0.0 46.3 0.0 27.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.6 17.2 0.0 21.4 18.0 15.3 10.8 17.8 2.4 0.3 43.2 2.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 4.3 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 SHMT1 "CSHMT, MGC15229, MGC24556, SHMT" ENSG00000176974 "Serine hydroxymethyltransferase 1" P34896 17 18327860-18363563 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "One-carbon metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 168.5;liver: 398.7" "Group enriched" "Detected in many" 4 "Hepatocytes: 307.7;Proximal tubular cells: 435.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA023314, HPA078682" Enhanced Supported Nucleoplasm,Cytosol NA NA 1500000 "Cluster 44: Non-specific - Transcription" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 18: U-2197 - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol Nucleoplasm "HPA023314: AB_1856830, HPA078682: " "unprognostic (4.76e-2)" "unprognostic (1.98e-2)" "unprognostic (5.46e-2)" "unprognostic (3.76e-1)" "unprognostic (2.45e-1)" "unprognostic (8.44e-3)" "prognostic favorable (2.52e-4)" "unprognostic (7.55e-3)" "unprognostic (4.50e-1)" "unprognostic (2.42e-1)" "unprognostic (2.14e-1)" "unprognostic (1.70e-1)" "prognostic favorable (8.54e-6)" "unprognostic (1.70e-2)" "unprognostic (2.66e-1)" "unprognostic (2.57e-3)" "unprognostic (4.04e-2)" 37.5 9.4 8.1 4.0 9.4 9.5 36.3 12.6 9.5 13.6 7.1 17.5 13.8 7.6 4.9 59.2 13.1 7.7 5.7 8.8 8.5 168.5 398.7 10.3 9.0 10.8 9.3 11.7 8.8 85.7 4.1 7.7 10.7 10.1 6.1 3.1 30.0 10.0 18.8 22.6 24.4 3.7 8.0 21.7 13.3 12.8 9.4 21.1 23.5 18.6 17.6 11.5 19.3 16.0 39.6 28.9 5.5 34.5 29.9 15.8 63.0 11.3 10.3 30.8 31.2 22.1 22.5 26.8 27.8 3.6 16.4 18.8 32.4 39.7 24.3 17.3 30.6 13.0 39.9 21.6 7.2 4.4 11.0 21.1 13.6 23.1 7.2 10.9 9.7 32.3 10.0 10.9 11.3 12.4 46.0 13.9 17.4 43.6 5.1 29.7 48.5 34.7 69.3 17.0 24.0 5.3 82.7 14.9 21.4 50.2 64.5 19.4 2.6 5.7 14.0 71.4 17.6 10.7 20.5 7.1 10.3 12.7 16.5 10.2 4.7 5.2 5.3 5.9 8.1 4.4 6.6 5.5 3.5 3.7 6.8 6.4 0.2 8.5 5.2 1.1 11.2 4.3 8.1 9.4 12.6 9.5 8.8 8.5 10.8 9.3 10.7 8.0 9.4 16.0 11.2 12.8 31.0 3.3 10.4 10.3 21.7 16.5 18.8 3.1 22.7 13.8 2.7 42.9 11.2 36.8 4.2 23.7 5.2 8.9 82.2 13.7 10.9 6.2 1.9 7.4 1.2 28.0 5.2 7.7 76.1 8.0 9.2 10.1 8.2 9.9 13.6 307.7 39.6 0.0 4.8 12.9 4.1 36.8 3.5 5.5 5.9 17.2 12.4 9.4 4.4 33.8 5.2 2.0 11.4 5.3 9.7 3.0 20.3 5.9 53.7 435.7 3.5 4.2 19.7 8.1 4.4 30.0 21.4 35.4 10.5 8.5 10.1 4.9 32.2 10.9 SHQ1 "FLJ10539, Shq1p" ENSG00000144736 "SHQ1, H/ACA ribonucleoprotein assembly factor" Q6PI26 3 72749277-72861914 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 33.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MOLT-4: 113.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042792 Uncertain Supported Nucleoplasm NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Nucleoplasm "HPA042792: AB_10959736" "unprognostic (1.10e-2)" "unprognostic (1.03e-1)" "prognostic favorable (2.83e-4)" "prognostic favorable (6.49e-4)" "unprognostic (2.05e-1)" "unprognostic (4.54e-3)" "unprognostic (9.21e-3)" "unprognostic (3.19e-2)" "unprognostic (8.89e-2)" "unprognostic (6.78e-3)" "unprognostic (3.76e-1)" "unprognostic (5.28e-2)" "unprognostic (7.30e-3)" "unprognostic (3.59e-3)" "unprognostic (3.21e-2)" "unprognostic (1.41e-2)" "unprognostic (1.28e-1)" 5.9 7.0 7.3 8.1 10.1 9.2 8.1 7.1 7.6 6.7 6.1 8.8 6.7 7.1 11.4 6.4 10.7 5.6 10.1 5.1 6.6 7.4 8.0 6.2 8.9 7.1 7.0 7.6 7.0 8.5 4.6 5.3 7.4 5.7 8.7 5.5 5.7 6.0 9.1 7.5 6.1 8.0 5.2 7.0 6.4 10.0 8.0 15.3 8.2 8.6 10.0 8.4 5.1 10.4 13.5 18.1 12.0 20.3 15.7 19.2 12.1 21.8 15.8 22.4 24.6 14.5 10.7 22.4 10.2 15.2 18.2 10.9 24.9 20.5 27.5 20.1 19.6 23.3 14.1 17.3 15.9 39.7 18.8 19.2 15.4 33.1 13.6 10.4 21.2 35.8 19.0 13.5 18.5 20.2 113.4 14.1 33.9 41.5 22.7 27.1 18.8 17.3 19.7 17.6 7.6 30.4 20.3 14.3 10.6 16.0 14.7 14.9 15.1 18.0 17.5 30.1 19.5 24.9 53.8 32.7 16.1 32.0 18.3 0.9 11.9 4.3 14.2 13.5 19.1 13.7 15.8 15.4 12.3 13.3 17.7 15.4 0.5 24.2 12.3 17.6 14.4 14.5 7.3 10.1 7.1 7.6 5.1 6.6 7.1 7.0 7.4 5.2 8.0 10.4 5.9 12.8 6.9 8.8 8.3 13.3 4.3 6.9 5.7 7.5 7.2 5.3 9.5 4.3 6.5 5.5 0.0 6.1 9.9 4.3 7.9 8.6 6.9 11.5 9.6 9.1 4.2 10.3 12.1 6.1 7.9 7.1 5.6 8.0 15.2 6.6 11.4 7.6 6.9 3.3 13.5 6.8 4.1 6.6 6.2 1.9 5.9 5.7 5.4 20.6 4.1 3.2 2.1 16.1 33.9 6.5 4.3 5.7 6.1 5.1 4.7 5.7 16.2 5.4 0.0 8.0 5.9 9.1 19.5 10.8 10.2 5.7 7.6 14.8 9.3 3.9 SHTN1 "KIAA1598, shootin-1, shootin1" ENSG00000187164 "Shootin 1" A0MZ66 10 116881477-117126586 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "brain: 128.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 31 "classical monocyte: 19.7;intermediate monocyte: 12.9;myeloid DC: 19.3;non-classical monocyte: 6.6;plasmacytoid DC: 12.9" "Group enriched" "Detected in many" 42 "dendritic cells: 19.3;monocytes: 19.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037942, HPA037943" Enhanced Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA037942: AB_2675748, HPA037943: AB_10671637" "unprognostic (1.00e-1)" "unprognostic (2.50e-2)" "unprognostic (6.77e-3)" "unprognostic (2.81e-1)" "unprognostic (7.85e-2)" "unprognostic (1.61e-1)" "unprognostic (2.42e-2)" "unprognostic (1.03e-1)" "unprognostic (2.56e-1)" "unprognostic (1.35e-1)" "unprognostic (2.49e-1)" "prognostic unfavorable (5.07e-4)" "unprognostic (2.17e-2)" "unprognostic (1.48e-1)" "unprognostic (2.47e-1)" "unprognostic (1.85e-1)" "prognostic unfavorable (5.08e-6)" 1.9 4.0 63.2 4.5 94.5 0.7 4.9 42.7 54.1 2.9 10.0 4.3 4.1 2.4 4.6 3.1 2.9 3.8 1.6 46.9 73.9 4.7 7.6 6.2 2.9 77.5 70.1 3.9 12.2 8.0 6.2 3.1 69.5 4.2 5.2 10.6 6.7 1.4 0.3 5.6 4.8 2.0 48.6 4.5 5.7 6.4 79.5 2.7 7.5 0.8 2.3 2.1 2.1 128.1 24.2 13.4 1.3 2.8 0.0 0.0 12.8 2.0 5.3 4.0 7.6 15.1 15.5 0.0 4.0 7.4 11.8 12.2 10.6 8.9 4.1 0.0 11.0 0.0 14.5 8.9 1.7 4.3 3.7 0.5 7.5 4.0 7.5 10.3 9.7 6.4 6.7 0.1 2.8 9.6 0.0 0.1 5.0 4.8 8.9 0.0 17.5 5.4 10.3 3.3 14.5 5.7 16.0 23.3 13.8 15.7 18.4 3.8 17.0 1.4 9.4 0.1 11.7 2.4 0.1 0.0 7.1 0.0 7.2 0.0 19.7 0.2 0.0 12.9 0.0 0.0 0.1 0.0 19.3 0.0 0.1 0.0 0.4 0.0 6.6 12.9 0.4 5.6 63.2 94.5 42.7 54.1 46.9 73.9 77.5 70.1 69.5 48.6 79.5 128.1 1.4 76.9 35.7 0.0 2.0 0.0 18.9 0.0 15.4 92.3 31.8 15.9 4.9 35.8 23.5 23.9 62.6 42.1 24.7 10.6 21.5 46.4 7.5 43.4 10.6 5.1 17.0 1.7 0.0 53.2 30.9 11.2 36.7 81.1 2.5 23.6 1.8 50.5 37.3 48.8 0.0 15.5 0.0 83.6 0.0 11.7 11.1 77.2 0.0 0.0 90.3 13.8 1.0 0.0 0.0 46.2 42.5 5.3 0.8 25.2 21.2 58.4 18.2 59.4 13.1 18.2 5.0 22.0 39.6 20.5 0.0 20.0 3.1 28.4 15.7 15.4 SIGLEC1 "CD169, dJ1009E24.1, FLJ00051, FLJ00055, FLJ00073, FLJ32150, sialoadhesin, SIGLEC-1, SN" ENSG00000088827 "Sialic acid binding Ig like lectin 1" Q9BZZ2 20 3686970-3712600 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Endocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 11 "Hofbauer cells: 78.6;Kupffer cells: 93.4;Macrophages: 42.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "classical monocyte: 1.5" "Lineage enhanced" "Detected in single" "monocytes: 1.5" "Cell line enriched" "Detected in single" 19 "THP-1: 2.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA053457 Supported "Intracellular and membrane" NA NA 260000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 19: Lung - Lung function" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "HPA053457: AB_2682158" "unprognostic (2.05e-1)" "unprognostic (9.27e-3)" "unprognostic (3.83e-4)" "unprognostic (4.87e-3)" "unprognostic (3.40e-2)" "unprognostic (1.06e-1)" "unprognostic (2.15e-1)" "unprognostic (6.98e-2)" "unprognostic (2.27e-2)" "unprognostic (1.68e-1)" "unprognostic (1.40e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (8.69e-5)" "unprognostic (8.71e-2)" "prognostic unfavorable (4.36e-4)" "unprognostic (1.11e-2)" "unprognostic (9.31e-2)" 23.0 13.7 2.0 7.7 2.9 12.3 8.6 1.9 6.5 1.8 7.5 10.2 5.1 2.0 1.8 2.2 7.0 8.5 6.4 1.8 2.2 3.9 8.4 16.7 12.7 10.2 3.3 2.7 1.6 0.5 2.3 18.8 10.9 1.9 6.6 0.3 5.4 1.2 3.7 3.0 11.2 7.7 5.0 18.9 5.1 2.5 10.9 3.6 3.7 2.6 1.9 7.6 3.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.4 2.0 2.9 1.9 6.5 1.8 2.2 10.2 3.3 10.9 5.0 10.9 3.9 0.5 3.2 4.4 0.0 0.1 0.4 0.0 0.0 0.0 0.4 0.0 0.3 2.4 0.0 0.6 0.0 2.1 0.9 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.4 0.0 0.0 0.2 0.2 0.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 78.6 0.0 0.3 0.0 0.0 93.4 6.3 0.1 0.0 42.6 0.0 3.7 2.1 0.2 0.0 0.5 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 1.4 1.0 0.0 0.1 0.6 0.6 1.9 0.4 0.0 0.0 0.0 SIPA1L3 "KIAA0545, SPAR3" ENSG00000105738 "Signal induced proliferation associated 1 like 3" O60292 19 37907208-38208369 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "GTPase activation" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 28.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 93.7;Inhibitory neurons: 87.3;Oligodendrocyte precursor cells: 99.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "A549: 59.6" "Low region specificity" "Detected in all" "HPA042072, HPA045480, HPA074988" Uncertain Supported "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 10: Brain - Neuronal signaling" "Cluster 18: U-2197 - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Nucleoplasm, Golgi apparatus" "HPA042072: AB_2677832, HPA045480: AB_2679342, HPA074988: " "unprognostic (4.24e-2)" "unprognostic (1.23e-1)" "unprognostic (1.86e-1)" "unprognostic (5.56e-2)" "unprognostic (9.99e-2)" "unprognostic (1.22e-2)" "unprognostic (1.31e-2)" "unprognostic (5.48e-2)" "unprognostic (3.11e-1)" "unprognostic (6.05e-2)" "unprognostic (3.15e-1)" "unprognostic (5.43e-2)" "unprognostic (9.26e-3)" "unprognostic (6.45e-2)" "unprognostic (4.94e-2)" "unprognostic (5.36e-2)" "unprognostic (1.96e-2)" 2.2 3.0 6.0 6.6 3.0 2.9 5.1 10.4 16.2 4.8 2.6 10.6 18.4 3.3 1.3 4.9 4.8 3.9 6.2 28.9 2.0 6.4 3.4 5.7 6.8 4.2 4.1 2.9 9.7 3.3 3.2 1.4 3.5 5.3 7.0 5.0 8.4 3.5 6.5 11.1 18.1 1.8 1.6 7.3 9.1 4.3 5.6 3.8 10.0 7.3 5.5 4.3 3.6 5.5 34.4 59.6 7.3 9.3 4.3 4.3 4.9 14.5 12.2 9.4 8.8 20.6 19.5 19.5 12.2 12.4 7.9 7.6 6.7 27.1 10.4 6.7 3.3 5.3 5.5 6.5 8.3 3.7 5.5 3.3 14.1 17.5 37.3 13.9 10.8 5.6 3.9 4.1 16.6 10.6 5.0 5.1 6.0 27.2 15.8 10.8 5.9 2.9 20.7 29.1 17.3 9.3 16.0 27.1 2.2 3.9 18.0 3.5 23.2 15.6 5.5 48.4 22.6 5.4 10.0 6.6 20.1 4.9 20.6 0.1 0.1 0.4 0.1 0.2 0.0 1.1 0.1 0.2 0.1 1.5 0.1 0.5 0.1 0.3 1.5 0.3 0.1 0.1 6.0 3.0 10.4 16.2 28.9 2.0 4.2 4.1 3.5 1.6 5.6 5.5 4.8 6.4 10.1 41.4 24.5 12.0 5.2 10.4 6.2 21.9 22.6 12.1 5.2 22.8 10.8 23.9 14.6 2.1 9.3 93.7 3.9 7.2 4.5 19.8 4.8 5.4 25.2 10.8 61.1 15.3 1.4 3.7 40.2 16.5 2.5 4.8 6.4 23.5 3.5 33.7 87.3 46.3 20.3 5.1 13.9 9.2 2.1 8.3 5.4 50.6 7.1 3.0 5.2 99.5 58.7 13.4 38.7 1.9 12.8 6.6 50.0 21.1 19.1 5.7 6.6 4.5 3.6 1.7 5.1 8.9 16.1 0.8 5.1 1.7 30.4 5.6 SIRT2 SIR2L ENSG00000068903 "Sirtuin 2" Q8IXJ6 19 38878555-38899862 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Autophagy, Cell cycle, Cell division, Differentiation, Immunity, Innate immunity, Meiosis, Mitosis, Neurogenesis, Transcription, Transcription regulation" Transferase "Cancer-related genes, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 302.1;tongue: 218.2" "Cell type enhanced" "Detected in all" "Early spermatids: 173.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004573, HPA011165" Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoli, Cytosol" Nucleoplasm "CAB004573: AB_2188600, HPA011165: AB_1856900" "unprognostic (2.15e-2)" "unprognostic (2.24e-2)" "unprognostic (2.88e-1)" "prognostic unfavorable (7.20e-7)" "unprognostic (3.75e-3)" "unprognostic (1.28e-2)" "unprognostic (2.85e-2)" "unprognostic (2.44e-3)" "unprognostic (2.73e-1)" "unprognostic (4.83e-2)" "unprognostic (2.97e-3)" "unprognostic (1.02e-1)" "unprognostic (1.90e-1)" "unprognostic (3.60e-2)" "unprognostic (1.19e-1)" "unprognostic (8.73e-2)" "unprognostic (1.70e-1)" 43.2 44.0 101.6 11.5 137.5 17.4 39.7 141.1 123.0 41.5 79.4 49.2 12.6 37.2 10.4 42.5 37.2 15.0 76.9 100.7 111.2 35.9 51.5 38.2 13.7 151.0 129.6 49.0 33.4 18.2 31.2 10.5 144.7 32.7 10.2 11.9 41.5 14.9 302.1 48.8 32.4 18.3 121.3 40.1 41.4 43.5 127.6 13.1 34.5 218.2 13.0 41.3 37.8 173.5 16.1 9.8 8.4 20.6 46.7 31.8 5.8 11.3 20.2 17.8 22.7 17.1 10.2 5.4 23.7 21.3 13.2 8.3 14.6 25.1 10.9 25.2 15.6 10.1 10.9 10.9 33.0 7.0 22.4 33.5 29.7 14.4 16.9 21.4 31.9 17.7 10.1 42.0 28.2 8.9 15.4 6.2 1.2 27.6 13.6 19.9 22.8 15.3 14.8 14.9 20.7 9.0 12.9 17.8 13.0 7.0 8.0 19.2 28.9 24.0 5.1 37.2 17.0 16.9 8.8 12.6 18.1 19.0 22.0 48.9 54.7 59.8 44.9 69.1 28.5 24.9 21.9 31.0 42.9 28.9 14.3 23.6 42.7 36.5 56.7 44.0 33.1 51.9 101.6 137.5 141.1 123.0 100.7 111.2 151.0 129.6 144.7 121.3 127.6 173.5 39.5 16.0 19.4 26.1 21.0 51.6 30.3 35.1 35.3 29.7 28.8 29.7 42.1 14.3 27.2 12.9 35.5 36.5 90.8 28.4 37.2 29.0 173.0 24.7 15.4 31.1 17.5 27.1 31.2 17.6 15.2 30.3 44.9 26.5 25.4 29.5 28.5 19.7 66.3 30.3 27.2 24.1 97.6 38.3 51.7 74.8 31.1 37.1 46.2 11.2 20.0 22.6 85.5 76.4 110.8 26.5 23.9 41.0 39.7 14.9 54.0 38.8 30.1 28.2 19.7 113.5 27.9 15.3 7.2 30.1 60.1 42.3 45.8 31.3 18.2 21.5 SIX1 DFNA23 ENSG00000126778 "SIX homeobox 1" Q15475 14 60643421-60658259 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Apoptosis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Cancer-related genes, Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 47.8;salivary gland: 51.1;skeletal muscle: 119.4;tongue: 46.3" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 30.7;Basal respiratory cells: 30.8;Club cells: 33.9;Ionocytes: 30.5;Prostatic glandular cells: 27.4;Respiratory ciliated cells: 67.1;Skeletal myocytes: 77.3;Spermatogonia: 25.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 36.3;LHCN-M2: 142.2;RH-30: 71.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA001893, CAB058690" Enhanced Supported Nucleoplasm,Nucleoli No No "Cluster 13: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Nucleoli "CAB058690: AB_2665581, HPA001893: AB_1079991" "unprognostic (3.62e-1)" "unprognostic (5.44e-2)" "unprognostic (5.09e-2)" "prognostic unfavorable (8.92e-6)" "unprognostic (1.33e-2)" "unprognostic (1.44e-2)" "unprognostic (2.04e-3)" "prognostic favorable (3.94e-4)" "unprognostic (1.40e-1)" "unprognostic (9.15e-2)" "unprognostic (6.45e-2)" "unprognostic (1.89e-1)" "unprognostic (3.06e-8)" "unprognostic (8.61e-2)" "unprognostic (2.13e-1)" "unprognostic (1.94e-1)" "unprognostic (3.86e-1)" 5.5 0.4 0.3 0.0 0.5 0.0 1.9 0.5 1.2 15.2 1.0 0.0 0.0 0.0 0.4 1.1 0.8 0.5 0.0 0.3 0.3 0.0 0.0 1.5 0.5 0.3 0.4 0.2 0.3 47.8 19.8 0.0 0.4 13.2 0.0 0.0 51.1 0.2 119.4 0.3 0.0 0.0 0.3 0.0 0.4 1.7 0.5 9.7 1.9 46.3 0.2 1.6 0.8 0.4 15.2 3.5 0.6 28.1 17.0 20.6 0.4 4.1 10.6 4.9 4.0 0.0 8.2 0.0 2.2 0.6 2.1 4.4 10.3 6.4 2.1 0.0 17.1 2.0 1.9 6.8 0.0 0.0 0.2 15.6 4.9 2.3 0.7 36.3 0.3 1.6 5.8 0.0 142.2 2.8 0.0 0.5 0.0 0.0 8.9 0.0 71.9 0.0 5.9 16.3 2.5 0.3 5.0 0.3 6.1 0.5 3.3 0.4 13.9 6.7 5.4 7.9 6.5 0.5 0.1 0.0 1.5 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.5 1.2 0.3 0.3 0.3 0.4 0.4 0.3 0.5 0.4 0.8 3.2 1.5 0.0 0.0 0.1 30.7 30.8 0.6 0.0 1.0 0.8 0.9 0.0 33.9 1.8 0.0 0.2 0.0 0.1 1.9 0.0 0.2 1.1 0.1 1.6 0.0 0.0 0.0 0.8 0.4 5.7 0.5 1.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 30.5 0.0 0.0 0.6 0.0 0.3 0.0 1.9 0.0 0.8 0.0 1.0 0.1 0.2 0.0 1.2 0.0 27.4 0.0 0.1 67.1 0.2 0.0 77.3 5.1 0.0 25.0 0.1 0.1 0.3 0.1 0.1 0.0 18.3 SLAIN1 "C13orf32, FLJ30046" ENSG00000139737 "SLAIN motif family member 1" Q8ND83 13 77697687-77764242 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "brain: 412.9" "Cell type enriched" "Detected in many" 5 "Oligodendrocytes: 1081.8" "Cancer enhanced" "Detected in many" "glioma: 25.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HEK 293: 58.1;HL-60: 78.8;MOLT-4: 90.5;REH: 62.1;SCLC-21H: 58.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "unprognostic (8.76e-5)" "unprognostic (1.78e-2)" "unprognostic (3.11e-1)" "unprognostic (3.25e-3)" "unprognostic (1.60e-1)" "unprognostic (3.78e-2)" "unprognostic (2.13e-1)" "unprognostic (1.39e-2)" "unprognostic (6.20e-2)" "prognostic favorable (9.07e-4)" "unprognostic (4.80e-3)" "unprognostic (3.83e-3)" "unprognostic (2.16e-2)" "unprognostic (4.53e-2)" "unprognostic (1.37e-1)" "unprognostic (3.34e-1)" "unprognostic (1.97e-2)" 2.9 10.3 180.6 5.5 311.6 17.7 7.0 222.0 215.1 5.5 32.8 5.3 3.0 7.4 12.7 4.3 18.3 3.9 6.7 156.3 184.7 8.9 8.1 10.8 11.5 277.3 271.1 7.9 11.7 20.6 8.3 3.8 277.7 7.4 3.0 59.5 10.6 6.0 3.3 2.9 4.0 5.3 210.3 8.7 12.2 34.0 235.0 27.2 11.4 4.9 11.2 5.3 2.3 412.9 0.3 3.5 41.1 0.9 0.0 0.0 7.1 0.2 0.0 0.1 0.0 4.0 8.6 32.8 2.1 0.1 0.1 0.2 39.3 0.0 0.0 41.4 58.1 28.0 7.6 0.7 1.1 78.8 2.0 0.0 0.1 0.0 0.0 4.6 1.6 45.0 0.8 41.9 0.0 1.1 90.5 7.8 15.7 28.4 12.9 62.1 3.6 0.1 19.3 3.3 58.6 29.7 0.0 11.4 7.9 13.5 0.0 35.1 0.5 0.5 1.7 0.4 11.2 41.3 20.2 38.9 4.5 9.1 2.5 0.0 0.0 0.0 0.8 0.1 1.2 0.3 1.0 0.9 0.1 0.2 1.1 1.8 0.0 0.3 0.1 0.9 2.3 0.5 180.6 311.6 222.0 215.1 156.3 184.7 277.3 271.1 277.7 210.3 235.0 412.9 0.7 12.8 10.8 27.7 5.5 0.8 3.0 0.0 2.8 7.9 5.4 2.8 4.7 8.6 1.9 3.7 16.7 1.8 8.8 0.1 1.9 2.1 79.0 14.8 2.3 3.4 9.0 3.0 72.7 2.6 0.2 1.5 7.1 23.0 0.0 5.2 3.6 5.7 0.3 3.3 91.9 0.8 0.0 1.2 0.8 18.0 1.5 1.7 7.2 30.0 0.8 95.5 6.2 209.1 1081.8 2.3 0.0 0.7 4.1 5.0 0.1 4.4 0.0 4.0 0.0 5.5 2.3 3.1 2.1 2.5 1.3 0.4 6.0 0.7 0.4 3.2 SLC10A6 SOAT ENSG00000145283 "Solute carrier family 10 member 6" Q3KNW5 4 86823468-86849384 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 9.1;skin 1: 13.4" "Group enriched" "Detected in some" 5 "Early spermatids: 59.5;Late spermatids: 191.7" "Group enriched" "Detected in many" 5 "cervical cancer: 3.5;head and neck cancer: 6.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 1.5;BJ hTERT+: 1.2;HaCaT: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA016662 Enhanced NA NA "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 25: Spermatids - Spermatogenesis" "HPA016662: AB_1669899" "unprognostic (2.79e-2)" "unprognostic (1.86e-1)" "unprognostic (1.05e-1)" "unprognostic (8.31e-3)" "unprognostic (5.88e-2)" "unprognostic (8.87e-3)" "unprognostic (1.32e-2)" "unprognostic (1.31e-1)" "unprognostic (1.07e-1)" "unprognostic (7.51e-2)" "unprognostic (1.08e-1)" "unprognostic (1.73e-1)" "unprognostic (3.84e-4)" "unprognostic (1.54e-1)" "unprognostic (2.06e-1)" "unprognostic (9.22e-2)" "unprognostic (5.89e-4)" 5.2 0.3 0.1 0.7 0.3 0.0 2.8 0.1 0.2 3.1 0.0 0.4 0.1 0.5 0.3 9.1 0.6 1.0 0.7 0.1 0.4 0.1 0.1 0.3 0.1 0.2 0.3 0.1 0.7 0.6 0.2 0.1 0.3 0.4 0.3 0.0 1.5 0.2 0.7 13.4 0.2 1.0 0.1 0.2 0.3 4.3 0.9 0.3 1.0 1.1 1.2 0.9 4.7 0.7 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.5 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.2 0.1 0.4 0.2 0.3 0.3 0.1 0.9 0.7 9.3 0.0 0.0 6.2 0.0 13.8 0.0 0.8 0.0 0.0 0.4 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 59.5 1.7 1.0 2.6 0.0 0.0 2.5 0.0 0.1 0.6 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 1.2 191.7 1.5 0.1 0.0 2.8 0.0 0.0 0.0 3.5 4.8 0.1 0.0 0.4 1.2 0.1 0.0 0.0 0.1 0.0 0.0 0.2 1.2 1.2 0.6 6.0 24.9 0.0 0.0 0.0 0.0 0.2 SLC12A2 "BSC, BSC2, NKCC1, PPP1R141" ENSG00000064651 "Solute carrier family 12 member 2" P55011 5 128083766-128189677 "FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Symport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 75.6" "Cell type enhanced" "Detected in all" "Intestinal goblet cells: 480.6;Oligodendrocytes: 566.6;Undifferentiated cells: 370.0" "Cancer enhanced" "Detected in all" "colorectal cancer: 54.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 6.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "OE19: 153.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020130, HPA063697" Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" Vesicles "Plasma membrane" "HPA020130: AB_1854502, HPA063697: AB_2685094" "unprognostic (4.61e-2)" "unprognostic (2.63e-1)" "unprognostic (4.20e-3)" "prognostic favorable (8.60e-4)" "unprognostic (3.99e-1)" "unprognostic (5.65e-3)" "unprognostic (1.44e-3)" "unprognostic (1.81e-1)" "unprognostic (3.30e-1)" "unprognostic (2.95e-2)" "unprognostic (7.22e-2)" "unprognostic (1.39e-1)" "prognostic favorable (7.09e-4)" "unprognostic (1.63e-1)" "unprognostic (2.30e-1)" "unprognostic (3.79e-1)" "unprognostic (3.88e-3)" 8.4 17.5 15.0 10.8 48.4 4.4 43.9 46.3 23.2 7.2 40.4 48.5 41.7 8.4 2.4 4.6 6.0 39.4 6.1 13.5 31.1 6.6 4.2 10.3 5.6 40.8 43.1 5.4 6.1 14.7 5.5 4.9 38.6 23.5 58.9 16.8 75.6 2.6 15.4 28.4 49.1 10.2 27.1 4.5 61.8 8.0 32.4 4.1 8.6 8.3 6.0 7.3 3.5 64.8 13.5 65.3 65.8 25.6 16.1 10.4 13.6 12.2 9.1 8.6 8.9 26.4 20.9 19.9 16.1 10.6 7.8 39.5 12.7 14.0 13.2 20.0 15.8 5.7 11.4 3.8 4.9 7.3 9.5 11.1 5.0 19.1 11.2 6.4 14.2 8.5 9.4 13.2 13.4 14.2 13.0 6.1 7.7 153.6 21.1 7.1 18.5 8.2 10.0 45.0 11.5 7.3 24.6 10.6 9.9 7.0 5.9 3.7 24.1 21.2 14.2 16.3 15.7 11.0 10.7 21.6 11.2 4.2 17.6 0.3 0.4 0.2 1.1 0.7 1.9 1.7 1.0 1.4 0.6 2.1 1.1 1.6 0.2 2.4 0.5 6.4 1.1 0.3 15.0 48.4 46.3 23.2 13.5 31.1 40.8 43.1 38.6 27.1 32.4 64.8 38.3 16.0 46.2 23.8 20.5 22.9 20.1 44.9 10.8 76.6 186.9 86.7 18.0 137.2 52.1 33.1 127.2 1.4 34.4 48.2 1.9 68.6 55.8 33.1 43.1 44.2 74.4 2.5 160.6 48.2 2.7 21.3 199.3 38.4 18.4 28.8 12.8 8.8 4.2 80.8 73.2 480.6 57.0 8.6 12.0 95.3 85.4 11.4 204.5 105.9 2.5 22.6 11.3 55.3 566.6 50.1 60.6 29.0 20.2 131.6 38.8 10.6 19.6 86.4 72.3 33.9 64.3 29.1 27.1 14.9 30.0 1.4 21.1 14.1 370.0 21.5 SLC16A10 "MCT10, TAT1" ENSG00000112394 "Solute carrier family 16 member 10" Q8TF71 6 111087503-111231194 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 53.7;skeletal muscle: 41.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 32.8;Excitatory neurons: 33.9;Inhibitory neurons: 47.8;Macrophages: 33.8;Melanocytes: 44.4" "Cancer enriched" "Detected in many" 6 "testis cancer: 4.5" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 1.7;T-reg: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HAP1: 49.4;HEK 293: 20.2;RPMI-8226: 37.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA016860 Approved Supported "Vesicles,Cell Junctions" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 25: RPMI-8226 - Immune response" "Cluster 41: Macrophages - Immune response" "Vesicles, Cell Junctions" "HPA016860: AB_2189211" "unprognostic (2.03e-1)" "unprognostic (2.08e-1)" "unprognostic (6.11e-2)" "unprognostic (3.56e-4)" "unprognostic (2.24e-1)" "unprognostic (2.15e-1)" "unprognostic (1.64e-1)" "unprognostic (1.89e-1)" "unprognostic (1.86e-3)" "unprognostic (5.22e-1)" "unprognostic (1.74e-2)" "unprognostic (1.06e-1)" "unprognostic (1.10e-3)" "unprognostic (2.73e-1)" "unprognostic (1.60e-1)" "unprognostic (1.33e-1)" "unprognostic (1.91e-1)" 2.9 5.5 1.4 3.0 8.6 0.8 0.8 4.2 3.4 0.6 53.7 1.2 8.5 0.5 1.4 0.8 0.8 1.5 2.3 2.0 1.2 10.0 13.5 4.6 0.9 1.1 5.0 0.9 29.7 7.9 1.0 23.7 2.8 1.3 1.8 0.7 3.1 0.2 41.2 15.3 5.0 0.3 0.2 1.8 5.3 4.2 9.6 10.9 2.7 6.0 1.3 1.9 1.2 1.1 0.9 1.0 0.4 2.2 0.1 0.1 3.1 0.0 0.2 0.8 1.2 9.0 0.4 5.2 1.4 0.3 2.5 0.1 49.4 0.1 1.0 0.1 20.2 8.2 0.7 7.4 0.1 7.6 7.4 0.0 0.0 0.1 0.0 0.2 0.0 10.9 1.4 0.2 0.1 3.6 9.8 0.8 14.6 0.2 3.2 5.4 6.8 37.2 0.0 0.5 10.7 3.3 0.2 0.7 1.8 3.6 1.8 0.9 0.1 0.1 1.8 0.5 2.5 2.6 0.1 1.5 0.3 5.8 0.8 0.4 0.0 0.0 0.1 0.0 0.1 0.1 0.4 0.1 0.0 0.2 1.7 1.5 0.3 0.1 0.0 0.1 1.6 0.1 1.4 8.6 4.2 3.4 2.0 1.2 1.1 5.0 2.8 0.2 9.6 1.1 0.4 9.6 32.8 2.0 1.5 9.7 10.7 0.0 4.6 6.9 2.0 1.3 9.1 0.0 3.1 5.5 2.1 1.9 0.7 2.1 1.9 0.2 9.0 0.4 0.8 1.4 6.6 1.7 33.9 12.5 1.8 8.9 3.6 1.3 1.3 2.5 4.2 25.4 21.4 1.7 47.8 4.8 0.0 12.4 12.4 8.2 0.0 33.8 44.4 0.0 0.7 1.6 0.0 16.6 0.3 2.0 0.9 0.0 4.8 3.9 10.9 17.7 0.7 0.7 0.0 18.5 1.0 11.6 11.2 1.2 14.8 1.2 5.8 9.2 8.5 1.2 SLC16A3 "MCT3, MCT4" ENSG00000141526 "Solute carrier family 16 member 3" O15427 17 82217934-82261129 "Metabolic proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 198.3" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 1667.1;Syncytiotrophoblasts: 748.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 109.1" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB017490, HPA021451" Approved Supported "Nuclear membrane,Plasma membrane" NA NA 260000 "Cluster 52: Eosinophils - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane" "Nuclear membrane" "CAB017490: AB_2189333, HPA021451: AB_1853663" "unprognostic (2.49e-1)" "prognostic unfavorable (6.07e-4)" "unprognostic (4.31e-1)" "unprognostic (1.74e-1)" "unprognostic (3.47e-3)" "unprognostic (4.26e-3)" "prognostic unfavorable (1.19e-7)" "prognostic unfavorable (2.02e-5)" "unprognostic (2.52e-1)" "unprognostic (2.09e-2)" "unprognostic (4.35e-3)" "unprognostic (1.53e-1)" "prognostic unfavorable (3.71e-7)" "unprognostic (2.27e-1)" "unprognostic (4.00e-2)" "unprognostic (8.00e-2)" "unprognostic (1.36e-2)" 30.4 16.9 3.8 25.3 5.8 22.7 15.7 6.6 9.7 26.2 5.0 28.9 11.6 11.6 1.3 42.4 18.5 12.8 26.0 4.5 7.3 48.2 11.3 46.4 5.7 17.3 8.5 9.1 5.8 2.5 12.1 24.7 11.9 19.6 5.7 5.7 27.5 5.9 198.3 8.4 22.9 6.0 8.4 57.5 22.0 32.0 13.8 2.9 29.1 73.2 5.2 26.3 28.5 15.1 52.8 24.4 0.6 1.3 7.8 28.8 51.7 225.6 107.7 117.4 142.2 10.1 119.1 0.7 158.0 122.5 127.9 18.9 15.6 242.0 51.8 78.1 1.2 87.4 144.0 236.4 164.1 105.2 111.5 64.8 38.2 77.0 38.5 185.8 69.1 2.2 1.0 26.6 116.1 14.0 1.4 166.3 1.9 22.1 223.5 0.9 1.6 33.2 75.9 3.0 2.9 1.7 196.7 166.9 3.2 20.4 25.4 131.4 124.0 281.7 5.1 4.5 200.9 97.3 1.9 3.9 140.2 94.7 3.0 56.6 32.6 92.1 9.6 30.4 13.4 8.1 7.7 10.5 24.1 6.2 4.2 5.3 109.1 25.3 31.4 15.2 7.3 16.0 3.8 5.8 6.6 9.7 4.5 7.3 17.3 8.5 11.9 8.4 13.8 15.1 19.2 9.6 9.8 3.6 27.9 6.5 47.5 210.1 2.8 13.4 3.2 2.5 6.1 4.3 182.3 57.0 4.2 67.6 72.4 216.7 0.0 136.1 3.0 33.7 15.4 29.9 20.9 9.1 0.3 18.0 1667.1 17.2 45.3 65.1 75.0 15.9 16.8 1.1 271.0 127.9 0.3 28.3 148.5 99.9 84.6 3.8 3.1 168.6 14.2 9.4 184.9 20.3 40.2 0.0 1.0 305.5 190.2 3.8 35.7 16.5 62.4 5.6 91.1 11.6 0.0 1.6 50.5 1.9 9.5 1.6 6.7 748.8 38.5 0.8 33.4 119.6 SLC16A9 "C10orf36, FLJ43803, MCT9" ENSG00000165449 "Solute carrier family 16 member 9" Q7RTY1 10 59650764-59736002 "Metabolic proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adrenal gland: 151.3;kidney: 191.1" "Group enriched" "Detected in many" 4 "Astrocytes: 83.9;Distal enterocytes: 108.6;Proximal tubular cells: 252.6;Theca cells: 99.4" "Cancer enhanced" "Detected in many" "renal cancer: 21.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HAP1: 10.8;NTERA-2: 20.1;SuSa: 10.1;U-251 MG: 10.6;U-937: 18.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049286 Approved Approved "Nucleoplasm,Cell Junctions" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "Cell Junctions" "HPA049286: AB_2680699" "unprognostic (3.39e-2)" "unprognostic (6.91e-2)" "unprognostic (1.30e-1)" "unprognostic (1.27e-1)" "unprognostic (1.60e-3)" "unprognostic (1.76e-2)" "unprognostic (5.96e-2)" "unprognostic (3.50e-3)" "unprognostic (5.01e-2)" "unprognostic (2.11e-3)" "unprognostic (5.99e-2)" "unprognostic (4.60e-2)" "prognostic favorable (2.56e-6)" "unprognostic (7.57e-3)" "unprognostic (1.27e-2)" "unprognostic (3.72e-1)" "unprognostic (1.94e-1)" 1.2 151.3 12.8 1.2 12.8 1.7 1.7 11.9 14.8 18.5 18.4 12.5 0.4 16.2 5.2 10.9 22.0 3.1 3.4 12.9 16.6 191.1 2.5 1.1 1.7 14.0 13.7 34.1 3.0 29.2 6.9 0.1 12.0 7.8 16.7 5.6 2.9 10.2 4.3 0.4 1.2 7.2 13.3 40.8 6.0 8.9 12.3 1.2 13.9 2.8 2.8 2.2 9.0 15.0 0.0 0.3 5.2 6.8 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.3 0.0 0.7 0.0 0.0 0.9 10.8 0.0 0.0 0.0 1.8 0.1 0.3 0.1 0.1 2.3 0.0 0.5 0.2 0.0 2.8 0.1 0.4 5.4 8.0 0.1 0.6 4.2 3.0 0.0 20.1 2.0 9.3 3.6 0.2 7.2 0.0 0.3 3.4 9.6 0.1 0.4 0.0 10.1 3.4 4.5 3.2 0.5 1.1 0.1 10.6 0.0 0.0 0.0 0.0 18.6 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.8 12.8 11.9 14.8 12.9 16.6 14.0 13.7 12.0 13.3 12.3 15.0 0.3 0.0 0.0 83.9 1.0 0.1 2.1 9.4 0.6 4.3 3.1 1.5 3.9 0.0 26.2 7.3 0.0 0.0 0.0 108.6 25.4 1.0 0.2 2.3 2.0 1.5 20.0 4.2 2.5 0.0 1.7 4.1 3.6 2.4 0.0 28.4 0.4 0.0 0.1 3.3 4.8 19.1 4.1 18.8 0.7 1.5 13.7 1.5 3.6 1.9 0.6 11.8 0.0 14.6 1.0 0.1 23.2 12.0 0.0 17.7 2.2 252.6 7.4 1.0 0.0 2.4 3.4 0.3 0.2 17.0 0.1 0.0 0.7 99.4 11.9 6.5 SLC17A5 "AST, ISSD, NSD, SD, SIALIN, SIASD, SLD" ENSG00000119899 "Solute carrier family 17 member 5" Q9NRA2 6 73593379-73653992 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "parathyroid gland: 310.5" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "thyroid cancer: 47.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 99.9;ASC TERT1: 74.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044479 Supported "Plasma membrane,Cytosol" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane, Cytosol" "HPA044479: " "unprognostic (6.48e-3)" "unprognostic (7.95e-3)" "unprognostic (9.23e-2)" "unprognostic (1.45e-2)" "unprognostic (1.48e-1)" "unprognostic (1.08e-1)" "unprognostic (2.59e-3)" "unprognostic (4.44e-2)" "unprognostic (4.18e-2)" "unprognostic (2.60e-1)" "unprognostic (3.14e-2)" "unprognostic (8.29e-2)" "unprognostic (4.59e-2)" "unprognostic (2.50e-1)" "unprognostic (1.40e-1)" "prognostic favorable (3.52e-4)" "unprognostic (1.09e-1)" 10.4 10.5 5.9 6.4 6.0 6.8 13.8 6.2 7.0 10.7 5.9 20.4 16.4 9.4 44.6 8.4 5.3 10.4 8.5 6.5 8.5 31.9 17.6 13.2 5.3 6.5 7.0 4.0 11.6 310.5 9.9 21.7 7.8 16.8 22.1 18.3 30.3 14.7 5.4 7.1 21.1 10.6 5.7 7.0 14.4 6.1 7.1 4.5 43.5 6.2 5.6 12.6 6.3 7.6 7.4 9.9 9.7 15.6 99.9 74.2 12.8 23.8 59.4 6.3 22.0 6.6 17.6 6.8 11.2 32.9 14.8 12.6 13.7 5.9 11.2 4.8 15.5 2.8 5.1 15.4 19.4 5.6 10.8 34.2 8.8 14.2 9.7 26.4 16.2 9.0 7.1 7.2 22.3 4.9 2.3 3.3 7.1 30.9 5.7 5.0 12.1 28.5 16.0 20.2 3.8 6.7 4.8 14.0 14.4 14.0 6.3 34.1 23.5 3.0 2.8 12.1 5.7 20.4 30.6 1.9 10.5 11.6 9.0 13.3 7.9 3.3 6.0 7.4 5.8 3.9 6.6 5.8 7.6 2.4 5.4 6.0 5.7 8.9 4.8 5.5 6.6 4.9 5.9 6.0 6.2 7.0 6.5 8.5 6.5 7.0 7.8 5.7 7.1 7.6 8.8 22.4 20.7 16.3 8.2 9.6 13.2 13.7 5.7 8.2 22.6 5.5 6.8 18.6 17.4 51.5 29.2 19.4 11.0 46.4 3.9 14.2 36.6 16.6 7.8 13.8 12.1 3.8 47.7 13.7 13.5 25.8 14.8 19.6 14.5 3.2 23.9 32.9 64.6 0.0 46.8 47.7 20.3 24.8 22.7 48.3 7.5 25.4 10.6 14.0 11.2 8.3 13.4 17.6 16.3 19.2 17.5 11.3 20.6 29.1 23.9 36.3 21.5 28.9 0.0 10.5 9.1 8.4 3.6 10.2 11.2 22.8 11.0 2.9 19.2 30.7 SLC22A16 "CT2, FLIPT2, OAT6, OKB1" ENSG00000004809 "Solute carrier family 22 member 16" Q86VW1 6 110424687-110476641 "Metabolic proteins, Predicted membrane proteins, Transporters" "Differentiation, Ion transport, Spermatogenesis, Transport" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 20.5;testis: 21.4" "Group enriched" "Detected in some" 10 "Early spermatids: 34.9;Erythroid cells: 60.4;Late spermatids: 31.8;Spermatocytes: 43.1" "Cancer enriched" "Detected in single" 5 "endometrial cancer: 0.8" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "basophil: 5.7;classical monocyte: 6.9" "Group enriched" "Detected in many" 56 "dendritic cells: 4.0;granulocytes: 5.7;monocytes: 6.9" "Group enriched" "Detected in some" 18 "NB-4: 16.9;REH: 14.6;THP-1: 53.1;U-937: 30.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA036902 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 43: THP-1 - Innate immune response" "Cluster 6: Erythroid cells - Oxygen transport" "Plasma membrane, Cytosol" "HPA036902: AB_10672274" "unprognostic (1.01e-1)" "unprognostic (1.88e-2)" "unprognostic (5.11e-3)" "unprognostic (2.19e-3)" "unprognostic (2.70e-4)" "unprognostic (1.45e-1)" "unprognostic (8.15e-2)" "unprognostic (6.93e-2)" "unprognostic (1.48e-2)" "unprognostic (4.98e-2)" "unprognostic (1.02e-3)" "unprognostic (2.49e-1)" "unprognostic (2.61e-6)" "unprognostic (5.78e-4)" "unprognostic (2.72e-2)" "unprognostic (2.74e-2)" "unprognostic (2.65e-2)" 0.3 0.0 0.1 0.6 0.2 20.5 0.1 0.2 0.2 0.2 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.1 0.4 0.0 0.2 0.2 0.0 0.0 3.8 0.0 0.5 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 1.8 0.2 0.5 0.0 21.4 0.1 1.2 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.9 0.0 0.0 0.0 14.6 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 53.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 30.9 0.0 5.7 6.9 1.3 0.0 1.5 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 1.5 0.1 0.2 0.2 0.2 0.1 0.1 0.2 0.2 0.3 0.2 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.9 0.4 0.1 0.0 0.0 60.4 0.1 0.0 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.0 2.7 0.0 0.1 0.0 0.0 1.8 0.5 31.8 1.5 1.1 0.0 0.0 1.8 0.0 0.0 0.0 0.5 0.0 0.0 0.4 0.3 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.1 43.1 0.4 0.0 0.4 0.0 0.1 0.0 0.0 0.0 SLC22A23 "C6orf85, FLJ22174" ENSG00000137266 "Solute carrier family 22 member 23" A1A5C7 6 3268962-3457050 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 50.9" "Cell type enhanced" "Detected in many" "Early spermatids: 86.8;Late spermatids: 229.3;Oligodendrocytes: 285.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "T-47d: 31.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014697 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 45: Intestine - Brush border" "Cluster 28: BEWO - Transcription regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Vesicles" Cytosol "HPA014697: AB_1844371" "unprognostic (4.58e-2)" "unprognostic (2.48e-1)" "unprognostic (1.05e-1)" "prognostic favorable (6.57e-4)" "unprognostic (5.16e-3)" "unprognostic (3.25e-3)" "unprognostic (1.40e-1)" "unprognostic (4.53e-3)" "unprognostic (9.74e-2)" "unprognostic (2.87e-2)" "unprognostic (1.07e-2)" "unprognostic (2.62e-2)" "prognostic unfavorable (2.39e-4)" "unprognostic (8.91e-2)" "unprognostic (4.30e-1)" "unprognostic (4.06e-2)" "unprognostic (1.74e-1)" 7.3 3.4 17.7 4.5 28.9 9.6 8.4 25.4 25.0 9.1 1.8 18.4 20.7 4.1 12.2 23.7 11.0 4.9 3.6 16.2 18.6 7.7 18.1 8.3 4.4 29.9 29.7 4.1 15.5 27.1 8.8 8.5 30.4 18.6 14.8 4.8 14.6 2.4 8.9 17.1 22.4 2.8 22.1 6.3 26.5 11.5 30.2 7.2 5.6 7.8 5.9 4.3 15.5 50.9 4.3 10.1 20.1 22.6 7.2 7.8 26.6 0.7 0.3 1.2 0.5 22.5 0.7 1.0 2.5 4.8 18.2 6.1 4.2 10.8 0.4 3.5 13.1 10.4 3.9 18.9 1.0 0.7 0.6 2.0 21.3 19.4 1.0 4.3 0.7 5.4 9.6 5.3 0.7 5.3 1.0 2.4 7.1 23.2 3.9 2.2 1.3 18.1 0.1 26.9 2.4 0.3 5.7 7.8 7.0 20.9 31.8 0.2 5.6 12.0 4.0 15.9 2.6 12.7 0.2 0.4 21.2 0.7 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.2 17.7 28.9 25.4 25.0 16.2 18.6 29.9 29.7 30.4 22.1 30.2 50.9 22.6 6.4 17.5 46.7 1.0 11.6 5.0 18.7 4.6 8.0 9.5 8.1 2.8 10.0 18.0 5.5 8.4 16.1 0.5 43.3 0.0 2.9 86.8 11.6 2.5 8.2 4.2 11.0 59.9 8.0 1.3 1.9 39.8 4.1 0.0 13.1 6.4 12.7 12.9 0.0 67.4 49.7 12.2 13.0 3.0 229.3 1.8 4.8 3.6 77.8 6.4 8.6 0.0 45.8 285.5 6.1 20.5 0.7 0.4 13.9 34.3 4.2 42.0 3.5 0.0 4.5 2.6 2.5 1.2 10.3 12.6 9.2 1.3 0.1 25.3 4.5 SLC25A18 ENSG00000182902 "Solute carrier family 25 member 18" Q9H1K4 22 17563450-17590995 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "brain: 143.8;choroid plexus: 90.7;liver: 111.5" "Group enriched" "Detected in many" 4 "Astrocytes: 195.2;Hepatocytes: 72.8" "Group enriched" "Detected in some" 5 "glioma: 10.6;liver cancer: 11.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 3.8;BEWO: 8.5" "Low region specificity" "Detected in all" HPA068110 Approved Nucleoplasm,Mitochondria NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 28: BEWO - Transcription regulation" "Cluster 64: Astrocytes - Nervous system maintenance" Mitochondria Nucleoplasm "HPA068110: " "unprognostic (2.15e-1)" "unprognostic (6.07e-2)" "unprognostic (4.95e-2)" "unprognostic (1.01e-1)" "unprognostic (3.79e-1)" "unprognostic (3.98e-2)" "unprognostic (1.00e-1)" "unprognostic (1.89e-1)" "unprognostic (1.45e-2)" "unprognostic (2.72e-2)" "unprognostic (8.70e-4)" "unprognostic (1.44e-1)" "unprognostic (3.92e-2)" "unprognostic (1.67e-2)" "unprognostic (1.29e-1)" "unprognostic (5.24e-2)" "unprognostic (1.62e-1)" 14.4 1.0 130.1 0.3 132.1 0.1 7.2 116.5 141.1 2.5 90.7 2.9 0.3 2.9 0.2 0.3 3.8 0.9 2.8 119.4 123.3 1.9 111.5 1.2 0.3 121.7 129.2 1.2 1.1 0.2 1.5 0.1 112.5 7.8 0.1 1.9 0.5 0.4 6.2 1.2 1.9 0.5 106.5 4.8 1.5 4.2 143.8 0.3 0.6 4.0 0.1 0.8 1.4 110.7 0.3 0.6 2.2 0.4 3.8 0.0 8.5 0.3 0.0 0.0 0.0 0.2 0.2 0.2 0.2 0.0 2.5 0.7 0.0 0.0 0.0 0.3 1.0 0.3 0.3 0.5 1.5 0.3 0.4 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.4 0.3 0.0 0.4 0.1 0.5 2.0 0.9 1.4 2.9 0.8 0.0 0.1 0.4 0.8 0.3 0.2 0.4 0.7 1.6 2.5 1.0 0.1 0.1 0.3 0.2 0.3 0.9 1.2 0.0 1.8 0.2 0.4 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 130.1 132.1 116.5 141.1 119.4 123.3 121.7 129.2 112.5 106.5 143.8 110.7 1.0 28.9 10.3 195.2 0.3 0.0 0.3 0.1 0.6 0.6 0.3 0.0 1.5 5.7 7.0 0.0 0.0 0.5 0.0 0.0 0.0 0.3 0.6 0.4 0.9 1.7 0.0 10.7 2.0 0.0 0.3 4.7 0.0 0.7 6.3 8.5 3.6 72.8 0.3 0.0 3.0 0.3 0.0 4.1 0.3 0.6 0.9 3.9 0.0 10.3 0.1 2.2 1.0 13.0 11.5 0.0 0.0 2.6 0.1 4.3 0.1 0.8 15.8 3.4 0.0 2.7 2.5 4.8 5.9 0.0 0.1 1.8 2.6 2.6 0.0 0.2 SLC25A19 "DNC, MCPHA, MUP1, TPC" ENSG00000125454 "Solute carrier family 25 member 19" Q9HC21 17 75272981-75289510 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 82.2;Langerhans cells: 160.3;Spermatocytes: 79.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021936 Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Mitochondria "HPA021936: " "unprognostic (2.28e-1)" "unprognostic (7.05e-3)" "unprognostic (8.21e-2)" "prognostic unfavorable (8.72e-5)" "unprognostic (2.31e-1)" "unprognostic (1.65e-1)" "prognostic unfavorable (1.21e-7)" "unprognostic (6.71e-2)" "unprognostic (2.73e-1)" "unprognostic (2.85e-1)" "unprognostic (7.72e-2)" "unprognostic (1.77e-3)" "unprognostic (2.71e-3)" "unprognostic (3.58e-2)" "unprognostic (4.44e-2)" "unprognostic (1.17e-1)" "unprognostic (2.13e-1)" 10.9 31.2 11.6 16.0 12.4 8.0 6.4 13.1 13.3 7.3 12.4 9.8 9.4 6.7 2.4 8.6 6.3 6.2 10.6 11.7 12.6 10.9 8.8 11.7 22.9 14.9 12.6 6.2 8.8 8.1 4.8 12.1 13.2 6.1 8.8 3.1 6.2 3.7 14.5 4.9 8.5 7.1 13.0 14.6 10.9 33.0 14.7 8.6 6.0 16.7 18.8 11.5 5.7 14.7 28.3 34.8 6.2 18.4 13.6 7.0 20.0 18.1 7.0 20.3 20.5 59.8 17.4 89.8 12.8 6.4 17.7 24.7 43.5 20.9 25.3 26.5 70.5 41.1 40.4 58.4 11.5 58.7 44.9 6.1 11.6 31.5 25.2 4.7 33.9 44.9 51.0 41.9 6.5 59.3 61.8 59.3 13.5 55.3 67.8 47.4 19.8 85.1 14.1 19.7 60.7 15.3 19.3 51.4 22.2 10.2 32.1 47.3 12.0 12.1 24.1 23.5 49.0 102.7 53.4 95.8 9.5 66.9 15.5 0.3 21.0 2.3 16.2 25.2 16.6 36.3 12.7 15.4 24.9 29.7 14.2 14.7 1.7 10.0 14.8 31.0 17.7 14.5 11.6 12.4 13.1 13.3 11.7 12.6 14.9 12.6 13.2 13.0 14.7 14.7 5.1 6.4 6.7 3.3 27.6 15.2 10.8 6.0 2.8 1.2 5.4 7.5 0.6 2.8 6.1 7.3 2.1 7.5 13.3 8.6 23.5 6.5 18.0 5.6 8.7 6.7 3.0 11.1 3.1 5.3 82.2 8.6 9.7 3.5 11.4 2.7 2.5 2.9 44.1 3.3 3.5 6.2 4.1 9.5 160.3 24.1 3.1 31.5 24.9 4.7 38.8 1.6 11.3 2.0 2.4 5.1 8.6 3.4 26.5 14.1 6.5 6.4 3.9 6.0 6.6 5.9 10.0 79.6 11.9 7.9 12.9 8.9 12.5 11.4 11.0 9.7 SLC25A21 "ODC, ODC1" ENSG00000183032 "Solute carrier family 25 member 21" Q9BQT8 14 36677921-37172606 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" Transport "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 6.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 27.8;Excitatory neurons: 14.1;Exocrine glandular cells: 10.0;Inhibitory neurons: 10.4;Oligodendrocyte precursor cells: 11.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "K-562: 26.4;Karpas-707: 54.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA000662 Uncertain NA NA "Cluster 23: Testis - Cell cycle regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 6: Erythroid cells - Oxygen transport" "HPA000662: AB_1080000" "unprognostic (6.81e-3)" "unprognostic (6.98e-2)" "unprognostic (7.21e-2)" "unprognostic (2.45e-1)" "unprognostic (2.78e-2)" "unprognostic (2.20e-1)" "unprognostic (2.44e-2)" "unprognostic (1.09e-1)" "unprognostic (7.32e-2)" "unprognostic (6.86e-2)" "unprognostic (9.16e-2)" "unprognostic (1.66e-1)" "unprognostic (6.70e-4)" "unprognostic (9.09e-3)" "unprognostic (1.95e-2)" "unprognostic (3.52e-1)" "unprognostic (1.07e-1)" 0.9 1.2 0.2 0.3 0.3 6.3 0.5 0.3 0.3 0.6 0.1 0.6 0.7 1.3 0.2 1.2 0.7 0.6 1.3 0.2 0.4 1.6 0.4 0.5 0.1 0.4 0.3 2.0 2.8 0.9 0.3 0.1 0.4 1.6 0.3 1.0 1.6 0.4 0.7 0.3 1.2 0.7 0.4 0.5 0.8 3.9 0.3 0.3 1.5 0.9 0.1 0.6 0.3 0.5 1.3 1.0 0.4 3.2 0.1 1.0 0.0 0.3 0.8 1.7 0.7 0.2 0.9 0.1 1.4 0.4 0.0 1.0 0.0 0.7 0.6 0.8 9.5 0.9 0.8 0.8 1.0 0.0 0.0 0.7 1.1 0.0 0.5 0.9 3.9 0.0 26.4 54.4 0.8 2.7 0.0 0.0 2.1 0.0 4.1 0.0 0.0 0.0 0.8 3.9 2.6 0.0 2.6 0.2 1.3 0.4 2.9 0.0 1.9 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.3 0.3 0.2 0.4 0.4 0.3 0.4 0.4 0.3 0.5 0.3 0.0 0.0 2.3 0.2 1.0 1.8 1.8 6.8 0.1 1.0 0.9 1.5 0.0 0.6 0.0 0.0 0.0 0.0 0.1 1.9 0.9 1.4 0.1 1.0 0.7 1.8 27.8 14.1 10.0 0.0 0.9 0.0 0.2 0.0 0.4 0.7 0.3 0.2 1.7 10.4 0.5 2.0 0.0 0.4 1.4 1.5 0.1 0.0 4.7 0.0 4.3 0.0 11.6 5.2 3.7 0.0 0.7 0.0 2.7 0.1 4.2 0.4 1.5 0.0 1.1 1.1 3.1 3.6 3.6 0.9 0.0 0.1 1.9 1.0 0.6 SLC25A33 "BMSC-MCP, MGC4399, PNC1" ENSG00000171612 "Solute carrier family 25 member 33" Q9BSK2 1 9539465-9585173 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 27.5" "Cell type enhanced" "Detected in all" "Early spermatids: 422.0;Late spermatids: 559.8;Spermatocytes: 358.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.8" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049982 Uncertain NA NA "Cluster 38: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA049982: AB_2680981" "unprognostic (1.61e-1)" "prognostic favorable (4.86e-4)" "unprognostic (2.94e-2)" "unprognostic (4.80e-2)" "unprognostic (1.89e-1)" "unprognostic (6.75e-2)" "unprognostic (5.18e-2)" "prognostic favorable (7.02e-4)" "unprognostic (1.88e-3)" "unprognostic (1.07e-1)" "unprognostic (8.59e-2)" "unprognostic (2.77e-1)" "unprognostic (4.55e-3)" "unprognostic (7.27e-2)" "unprognostic (1.19e-1)" "unprognostic (4.25e-2)" "unprognostic (3.77e-2)" 11.3 3.4 12.4 2.6 13.6 9.0 6.0 15.1 13.8 2.5 11.9 4.6 2.2 3.0 12.6 2.9 3.0 3.7 5.2 12.2 14.5 10.0 12.6 2.7 3.3 14.1 14.7 2.7 3.7 3.9 5.6 1.4 13.7 4.1 3.7 11.2 5.4 2.0 18.1 2.5 2.6 2.7 14.5 2.3 4.4 13.4 15.8 3.5 5.1 27.5 3.5 4.0 2.3 14.5 6.9 3.1 8.7 13.4 7.0 4.0 5.6 6.5 6.1 10.8 9.5 6.9 5.2 19.8 7.8 5.4 11.3 2.8 22.2 4.3 13.3 15.3 13.9 19.5 4.2 27.5 15.1 19.6 14.8 4.8 7.5 10.8 5.2 2.6 6.4 14.5 19.2 10.0 6.1 7.2 12.5 13.4 10.7 12.5 7.3 16.5 9.2 12.8 6.9 3.8 15.1 9.7 7.3 22.2 20.0 7.5 8.2 14.2 2.8 6.8 9.0 9.2 8.4 11.8 23.6 33.5 4.9 21.6 8.4 2.8 0.3 0.1 0.5 0.4 0.3 0.8 0.4 0.3 0.6 0.3 0.6 0.7 0.4 0.5 0.4 0.5 0.0 0.1 12.4 13.6 15.1 13.8 12.2 14.5 14.1 14.7 13.7 14.5 15.8 14.5 25.7 3.2 13.1 59.1 34.4 51.5 107.3 4.2 69.4 15.1 60.0 39.5 9.3 37.1 6.8 9.2 52.1 14.0 32.9 22.5 199.6 11.5 422.0 38.1 19.0 19.9 66.3 8.2 12.3 15.1 38.6 27.2 30.1 39.8 23.6 9.5 11.4 55.8 21.3 10.1 18.2 27.5 6.1 9.2 66.8 559.8 9.9 30.7 32.0 5.6 11.7 195.3 9.2 13.6 13.7 11.5 14.4 10.1 20.4 94.7 6.6 29.5 8.0 53.3 6.6 41.5 37.0 358.5 115.1 42.6 35.8 39.3 22.7 16.7 32.4 96.2 SLC25A37 "HT015, MFRN, MFRN1, MSCP" ENSG00000147454 "Solute carrier family 25 member 37" Q9NYZ2 8 23528956-23575463 "Metabolic proteins, Predicted intracellular proteins, Transporters" "Ion transport, Iron transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 138.4" "Cell type enhanced" "Detected in all" "Early spermatids: 707.8;Erythroid cells: 4197.2;Late spermatids: 1087.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 19 "neutrophil: 57.7" "Lineage enriched" "Detected in all" 19 "granulocytes: 57.7" "Cell line enhanced" "Detected in all" "HEL: 118.7;hTERT-RPE1: 65.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045680 Uncertain Approved Mitochondria,Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 36: HEL - Hemostasis" "Cluster 6: Erythroid cells - Oxygen transport" Mitochondria Cytosol "HPA045680: AB_10963693" "unprognostic (6.15e-3)" "unprognostic (7.33e-3)" "unprognostic (2.04e-1)" "unprognostic (1.40e-1)" "unprognostic (1.38e-1)" "unprognostic (5.12e-2)" "unprognostic (1.35e-1)" "unprognostic (1.68e-1)" "unprognostic (3.58e-2)" "unprognostic (1.40e-1)" "unprognostic (1.02e-2)" "unprognostic (2.24e-1)" "prognostic unfavorable (4.37e-6)" "unprognostic (8.27e-2)" "unprognostic (1.71e-1)" "unprognostic (2.37e-1)" "unprognostic (7.40e-2)" 14.5 41.9 13.5 16.5 16.9 138.4 17.9 13.4 21.0 26.8 15.2 11.4 50.6 9.8 6.0 9.9 17.2 6.7 15.3 13.4 14.0 20.1 25.2 26.4 6.0 15.0 14.1 23.0 29.5 10.9 15.0 8.0 15.4 35.5 5.7 10.3 36.7 7.5 16.2 10.1 21.8 5.7 13.0 46.1 11.1 6.8 15.0 2.8 14.6 12.7 5.0 13.4 20.4 14.6 9.6 10.3 10.7 9.9 13.7 16.8 15.7 7.4 9.6 5.3 5.9 10.4 19.9 15.3 8.7 6.3 34.5 12.0 9.9 20.0 7.2 2.3 4.9 118.7 19.4 3.7 11.5 6.7 4.4 14.5 19.2 11.6 11.5 65.9 8.4 12.3 26.3 7.5 8.5 4.2 8.1 28.1 5.4 11.6 7.5 8.3 5.3 6.0 16.4 5.2 3.2 4.6 10.1 15.2 7.6 10.0 4.4 10.3 13.3 25.6 3.8 15.3 14.5 5.9 2.4 9.4 24.1 16.1 16.5 1.4 3.0 2.7 1.1 1.1 0.9 2.3 0.6 0.5 2.8 1.5 2.1 1.2 57.7 1.3 1.5 0.6 1.3 1.4 13.5 16.9 13.4 21.0 13.4 14.0 15.0 14.1 15.4 13.0 15.0 14.6 43.5 38.5 61.7 36.6 45.5 93.3 125.2 95.8 28.5 35.6 120.0 49.1 35.6 61.5 75.8 77.3 68.8 44.6 19.1 78.4 15.6 93.8 707.8 33.1 68.6 94.5 20.4 4197.2 44.0 226.4 76.4 95.4 43.8 50.0 36.8 49.7 151.3 38.8 41.7 6.7 37.3 44.7 36.7 59.0 141.2 1087.9 52.5 86.8 69.4 73.1 45.5 30.5 10.3 16.1 21.9 176.9 47.7 37.2 24.0 347.1 189.0 34.1 42.5 59.7 19.7 55.9 52.3 24.6 42.3 23.3 53.8 18.3 32.4 86.7 70.3 137.6 SLC25A38 FLJ20551 ENSG00000144659 "Solute carrier family 25 member 38" Q96DW6 3 39383370-39397351 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 73.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041027 Approved NA NA "Cluster 46: Basophils - DNA binding" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 63: NK-cells & T-cells - Immune response" "HPA041027: AB_10794403" "unprognostic (3.82e-2)" "unprognostic (3.27e-2)" "unprognostic (1.96e-1)" "unprognostic (6.05e-2)" "unprognostic (1.13e-1)" "unprognostic (2.58e-1)" "unprognostic (1.25e-1)" "unprognostic (1.21e-2)" "unprognostic (3.94e-2)" "unprognostic (1.94e-1)" "unprognostic (1.26e-2)" "unprognostic (5.54e-2)" "prognostic favorable (1.58e-5)" "unprognostic (1.73e-1)" "unprognostic (1.47e-1)" "unprognostic (2.06e-1)" "prognostic favorable (7.29e-4)" 19.1 35.4 22.2 18.8 23.3 70.0 21.0 25.9 26.8 23.8 33.6 28.1 25.3 27.3 27.6 14.5 27.3 19.4 20.7 22.9 26.3 28.7 58.0 21.0 36.2 24.2 24.1 44.1 45.6 38.7 30.7 15.4 25.3 29.2 36.9 23.0 22.5 23.9 48.2 16.7 25.2 20.3 22.6 27.2 33.8 18.7 26.0 33.6 52.0 35.7 35.4 27.8 19.1 23.3 24.3 38.3 24.3 41.2 56.4 46.4 30.8 33.6 46.1 48.3 43.7 26.3 5.6 67.8 19.6 31.6 40.7 18.4 55.2 40.1 36.0 43.6 45.0 52.0 33.5 40.2 75.6 37.7 33.9 58.8 46.1 46.2 93.2 44.6 31.5 52.8 47.7 40.6 36.4 35.2 44.7 67.0 66.2 35.9 44.3 16.2 26.4 47.7 37.5 45.4 24.3 31.1 11.9 65.9 34.0 44.5 33.5 35.0 26.9 38.3 26.4 56.2 48.9 54.7 93.1 41.9 29.3 48.3 24.7 30.7 9.6 18.1 38.8 5.7 44.7 50.8 39.1 43.3 14.9 37.8 41.7 40.5 1.0 57.0 8.4 18.5 55.3 29.2 22.2 23.3 25.9 26.8 22.9 26.3 24.2 24.1 25.3 22.6 26.0 23.3 10.4 22.4 27.4 8.5 35.6 11.5 13.0 12.5 28.5 13.2 26.1 22.6 16.8 22.8 9.6 27.6 6.2 35.2 33.1 21.9 21.5 15.7 6.5 26.6 16.3 11.1 12.6 73.7 8.9 16.9 32.6 13.7 16.8 38.5 22.2 24.0 9.7 27.0 15.2 5.0 10.1 25.6 12.2 7.0 13.7 12.9 15.5 9.8 12.4 1.9 11.2 18.9 29.9 7.1 6.2 13.4 22.2 13.5 23.3 17.7 23.1 31.3 12.3 12.6 6.6 15.2 14.9 11.0 7.8 19.4 10.2 19.4 36.6 32.8 26.7 8.4 SLC25A4 "ANT1, PEO2, PEO3, T1" ENSG00000151729 "Solute carrier family 25 member 4" P12235 4 185143266-185150382 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Host-virus interaction, Transport" "Cardiomyopathy, Disease variant, FDA approved drug targets, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "heart muscle: 245.1;skeletal muscle: 190.8;tongue: 346.6" "Cell type enriched" "Detected in all" 4 "Cardiomyocytes: 4722.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046835, HPA071684" Approved Supported Mitochondria NA NA 380000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 38: Heart - Muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA046835: AB_2679831, HPA071684: AB_2686431" "unprognostic (4.19e-2)" "unprognostic (1.06e-2)" "unprognostic (3.11e-1)" "unprognostic (8.85e-2)" "unprognostic (1.37e-1)" "unprognostic (2.90e-3)" "unprognostic (8.25e-2)" "unprognostic (1.26e-2)" "unprognostic (7.87e-2)" "unprognostic (1.60e-1)" "prognostic favorable (3.41e-4)" "unprognostic (2.05e-1)" "prognostic favorable (0.00e+0)" "unprognostic (1.98e-1)" "unprognostic (1.05e-1)" "unprognostic (1.73e-1)" "unprognostic (8.28e-3)" 4.7 5.7 14.0 1.6 15.3 0.4 4.6 22.6 30.6 3.4 6.8 21.0 3.0 5.9 3.5 10.1 5.8 3.9 245.1 16.7 11.8 10.4 7.3 4.5 1.5 11.6 10.7 4.9 5.2 7.8 9.5 1.7 11.8 8.9 3.9 19.9 9.0 12.6 190.8 3.3 6.8 8.1 9.4 3.1 15.7 4.7 12.5 1.4 5.2 346.6 1.2 9.8 3.6 18.2 0.7 3.1 2.5 5.1 2.7 0.3 4.6 2.6 0.8 3.1 3.0 6.8 1.7 2.3 1.8 3.1 2.4 2.5 9.8 2.7 2.0 3.9 8.4 1.6 4.7 8.1 5.5 1.4 1.5 2.0 6.6 4.7 1.3 7.2 2.3 4.0 3.8 1.7 1.9 5.0 1.6 3.1 4.1 2.2 6.6 2.5 1.3 3.2 6.9 4.8 8.1 6.2 3.1 1.3 12.5 4.5 2.4 1.1 1.7 0.2 1.4 1.5 3.4 7.3 3.5 2.9 2.2 0.3 2.8 0.0 0.0 0.0 1.7 0.0 1.3 1.5 0.5 1.4 0.0 1.0 0.4 1.2 0.1 0.3 0.0 1.3 0.5 0.6 14.0 15.3 22.6 30.6 16.7 11.8 11.6 10.7 11.8 9.4 12.5 18.2 37.5 86.6 76.4 22.9 37.9 44.1 159.0 119.9 30.1 180.6 42.9 53.5 4722.0 115.8 80.0 71.7 104.3 69.2 41.1 44.4 988.0 75.3 20.6 77.8 7.4 80.1 53.8 3.0 35.1 74.1 56.5 120.1 54.0 33.6 12.0 18.6 27.5 92.1 65.9 159.9 43.7 40.6 215.7 8.5 13.8 16.7 46.6 6.8 190.3 19.7 9.0 541.2 16.5 26.7 29.2 51.4 28.5 112.8 76.4 59.1 113.8 178.3 144.0 221.0 105.2 134.5 402.7 28.0 34.0 33.2 18.2 40.5 27.7 23.7 54.2 50.7 SLC25A41 "APC4, FLJ40442, MGC34725" ENSG00000181240 "Solute carrier family 25 member 41" Q8N5S1 19 6426037-6433779 "Predicted intracellular proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 6.3;choroid plexus: 4.3;testis: 2.1" "Cell type enriched" "Detected in some" 4 "Early spermatids: 92.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 3.0;U-937: 1.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA043591 Uncertain NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 29: Early spermatids - Spermatogenesis" "HPA043591: AB_10964585" "unprognostic (1.87e-3)" "unprognostic (2.52e-3)" "unprognostic (6.81e-2)" "unprognostic (8.75e-2)" "unprognostic (2.67e-1)" "unprognostic (8.29e-4)" "unprognostic (4.43e-3)" "unprognostic (2.81e-2)" "unprognostic (9.26e-2)" "unprognostic (6.85e-2)" "unprognostic (2.19e-3)" "unprognostic (3.11e-2)" "unprognostic (2.03e-1)" "unprognostic (1.56e-1)" "unprognostic (3.63e-2)" "unprognostic (2.11e-1)" "unprognostic (1.24e-1)" 0.1 0.1 4.7 0.0 5.3 0.0 0.0 4.6 6.3 0.2 4.3 0.6 0.0 0.1 0.0 0.3 0.2 0.0 0.3 4.8 4.7 0.2 0.3 0.0 0.0 4.6 4.6 0.3 0.1 0.0 0.2 0.0 4.9 0.4 0.0 0.3 0.1 0.1 0.3 0.2 0.2 0.1 4.4 0.1 0.2 2.1 4.5 0.0 0.2 0.0 0.0 0.3 0.2 4.4 0.1 0.1 0.4 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.9 0.6 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 3.0 0.2 0.6 0.0 0.0 0.1 0.0 0.2 0.8 0.0 0.0 0.3 0.0 0.7 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 1.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 5.3 4.6 6.3 4.8 4.7 4.6 4.6 4.9 4.4 4.5 4.4 0.0 0.0 0.0 2.0 0.1 0.0 0.1 0.3 0.0 1.0 0.2 0.3 0.5 0.0 0.0 0.0 2.1 0.4 0.1 0.4 0.0 0.3 92.2 0.1 0.1 0.0 0.0 0.0 5.0 0.0 0.1 0.1 0.0 0.1 0.0 0.5 0.0 0.0 0.1 3.3 4.5 0.4 0.0 0.0 0.0 20.6 0.9 0.1 0.0 0.0 0.0 1.1 0.0 1.0 1.6 0.6 0.2 0.0 0.0 0.2 0.2 0.2 0.1 1.2 0.0 0.1 0.1 0.3 0.6 0.0 0.3 0.5 0.0 0.0 0.4 0.1 SLC25A46 ENSG00000164209 "Solute carrier family 25 member 46" Q96AG3 5 110738136-110765161 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 238.9;Late spermatids: 448.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039601, HPA071582" Approved Supported Mitochondria NA NA "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria "HPA039601: AB_2676592, HPA071582: AB_2686422" "unprognostic (1.86e-1)" "unprognostic (3.29e-1)" "prognostic favorable (8.41e-4)" "unprognostic (4.91e-2)" "unprognostic (2.27e-2)" "unprognostic (2.25e-1)" "unprognostic (2.34e-1)" "unprognostic (1.77e-2)" "unprognostic (5.14e-2)" "unprognostic (1.97e-2)" "unprognostic (1.67e-1)" "unprognostic (2.40e-1)" "unprognostic (2.25e-2)" "unprognostic (2.26e-1)" "unprognostic (2.62e-1)" "prognostic unfavorable (2.52e-4)" "unprognostic (1.98e-1)" 22.9 15.9 10.4 19.9 11.8 17.6 16.4 12.7 16.7 18.5 7.8 22.1 23.8 14.7 10.5 21.2 10.7 15.8 31.1 12.2 12.2 29.7 30.0 16.7 22.5 12.4 10.2 11.7 15.4 20.6 4.9 17.0 13.2 15.7 21.6 18.8 13.3 16.0 55.8 14.9 20.9 20.8 10.3 15.7 20.1 21.9 11.2 24.8 19.8 60.2 26.8 19.0 6.6 14.1 36.2 27.7 25.7 20.7 65.2 60.2 9.9 44.3 55.9 47.5 59.3 37.6 28.7 96.8 44.8 50.1 61.9 29.6 41.0 71.2 54.3 61.8 20.8 40.1 35.2 25.6 53.1 37.3 40.2 49.9 25.4 55.5 39.6 29.5 31.9 37.2 31.4 56.4 54.1 27.3 54.0 17.2 18.1 25.7 24.7 26.0 57.0 71.5 35.1 39.2 46.7 33.5 37.7 29.7 49.7 23.7 30.9 35.3 42.5 43.6 21.0 40.7 54.4 111.8 76.2 68.4 48.0 43.8 24.0 29.2 16.0 13.2 12.3 19.0 12.5 14.4 13.7 12.9 17.0 14.5 14.5 14.8 6.6 20.9 17.7 11.1 18.2 17.4 10.4 11.8 12.7 16.7 12.2 12.2 12.4 10.2 13.2 10.3 11.2 14.1 21.3 22.4 24.8 40.8 26.7 22.9 9.1 16.0 31.9 16.8 15.7 10.8 63.5 11.5 12.9 20.2 22.9 21.7 18.0 34.8 19.6 18.1 238.9 10.4 20.1 18.9 23.4 29.9 73.3 25.6 18.2 22.6 34.7 12.1 19.0 16.2 26.7 43.9 27.2 18.5 63.9 28.3 32.6 26.1 21.0 448.2 21.1 23.9 30.2 31.9 28.1 21.9 17.5 49.8 91.8 18.9 22.8 22.2 73.8 8.0 26.5 41.7 14.9 14.1 19.7 18.5 22.6 23.3 14.2 30.0 26.9 20.5 23.9 22.7 24.0 6.8 SLC26A8 ENSG00000112053 "Solute carrier family 26 member 8" Q96RN1 6 35943516-36024868 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Anion exchange, Differentiation, Ion transport, Meiosis, Spermatogenesis, Transport" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "testis: 44.0" "Cell type enhanced" "Detected in some" "Early spermatids: 54.1;Excitatory neurons: 15.8;Inhibitory neurons: 12.1;Late spermatids: 12.0;Spermatocytes: 64.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 11 "neutrophil: 2.3" "Lineage enriched" "Detected in single" 11 "granulocytes: 2.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA038081 Enhanced NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 78: Testis - Spermatogenesis" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA038081: AB_10670653" "unprognostic (8.18e-2)" "unprognostic (1.74e-1)" "unprognostic (6.71e-2)" "unprognostic (1.31e-2)" "unprognostic (2.46e-1)" "unprognostic (7.07e-3)" "unprognostic (2.93e-1)" "unprognostic (6.31e-2)" "unprognostic (1.11e-1)" "unprognostic (1.11e-1)" "unprognostic (1.85e-1)" "unprognostic (3.78e-1)" "unprognostic (4.63e-6)" "unprognostic (7.14e-2)" "unprognostic (4.24e-1)" "unprognostic (2.31e-1)" "unprognostic (5.24e-8)" 0.2 0.1 0.6 0.3 0.5 4.8 0.1 0.8 0.8 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.4 1.1 0.0 0.1 0.3 0.0 0.9 0.6 0.0 0.1 0.0 0.2 0.1 1.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.3 1.0 0.0 44.0 0.9 0.0 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.1 0.6 0.5 0.8 0.8 0.4 1.1 0.9 0.6 1.1 0.3 0.9 0.2 0.1 3.2 1.1 2.0 0.0 0.4 0.4 0.1 0.0 0.3 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 54.1 0.4 0.2 0.3 0.0 0.0 15.8 0.0 0.0 0.3 0.0 0.8 0.0 0.1 0.4 0.8 0.1 0.0 12.1 0.0 0.0 1.2 0.4 12.0 0.9 0.5 1.8 1.0 0.9 0.0 0.0 0.5 1.0 0.1 0.0 0.4 0.1 0.4 0.3 0.1 0.3 0.3 0.0 0.7 0.1 64.8 0.8 0.0 0.1 0.3 0.3 0.0 0.0 0.2 SLC27A1 "ACSVL5, FATP, FATP1, FLJ00336, MGC71751" ENSG00000130304 "Solute carrier family 27 member 1" Q6PCB7 19 17468769-17506168 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism, Lipid transport, Transport" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 84.5;Oligodendrocytes: 67.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 27.7;SK-MEL-30: 47.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076520 Approved "Plasma membrane,Mitochondria,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "Mitochondria, Cytosol" "HPA076520: AB_2732311" "unprognostic (1.48e-3)" "unprognostic (3.03e-2)" "unprognostic (5.72e-3)" "unprognostic (5.84e-2)" "unprognostic (2.16e-3)" "unprognostic (4.36e-2)" "unprognostic (8.56e-2)" "unprognostic (3.36e-2)" "unprognostic (9.03e-2)" "unprognostic (1.85e-2)" "unprognostic (1.12e-1)" "unprognostic (2.28e-1)" "prognostic favorable (4.70e-4)" "unprognostic (5.01e-2)" "unprognostic (2.25e-1)" "unprognostic (1.02e-1)" "unprognostic (1.12e-1)" 18.5 24.2 32.9 4.5 41.5 1.5 19.3 37.3 39.0 22.0 45.9 15.2 3.6 13.1 2.9 8.5 17.0 8.2 29.0 32.0 32.8 10.9 7.9 10.4 4.7 41.1 40.3 33.0 14.4 17.7 19.3 6.2 38.6 23.2 1.8 4.0 24.1 10.3 24.9 14.4 7.6 3.9 34.4 10.5 13.7 17.5 35.9 2.2 16.8 12.4 1.6 13.9 14.0 46.7 6.2 3.0 4.1 9.8 27.7 15.2 3.5 4.4 11.2 4.8 7.2 0.5 18.2 2.1 8.1 7.2 4.3 7.3 0.4 6.8 1.3 2.4 1.4 1.2 0.5 2.3 5.4 0.5 6.4 14.1 4.6 4.8 1.9 19.7 3.3 3.9 0.8 1.3 3.2 2.5 3.3 4.9 1.2 6.0 5.2 4.7 3.2 1.4 3.2 1.8 1.4 2.9 3.0 1.5 47.8 2.5 5.2 1.6 2.1 9.4 6.1 7.5 3.0 4.0 3.1 0.7 9.6 5.3 6.7 0.0 9.2 0.2 1.4 4.0 2.6 0.4 1.0 1.7 6.3 0.3 1.3 1.7 0.0 1.6 1.8 6.5 0.7 4.6 32.9 41.5 37.3 39.0 32.0 32.8 41.1 40.3 38.6 34.4 35.9 46.7 19.7 3.2 11.9 84.5 1.8 6.6 14.1 12.7 10.2 8.4 15.5 26.9 19.5 11.5 11.1 9.2 27.1 4.3 8.3 1.2 1.9 11.1 1.1 8.4 6.9 7.8 5.4 0.8 16.1 4.8 15.6 10.4 9.2 4.9 2.5 8.4 10.4 8.1 26.1 6.7 23.9 3.0 6.1 22.4 4.0 2.5 21.5 13.4 8.8 15.0 14.7 11.6 4.1 37.2 67.5 5.2 0.6 11.7 1.7 12.0 0.1 3.6 16.1 17.7 6.6 10.9 7.3 9.1 5.8 5.0 4.5 2.3 4.9 13.8 2.2 8.7 SLC2A14 "GLUT14, SLC2A3P3" ENSG00000173262 "Solute carrier family 2 member 14" Q8TDB8 12 7812512-7891148 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Differentiation, Spermatogenesis, Sugar transport, Transport" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "testis: 81.3" "Cell type enriched" "Detected in many" 5 "Spermatocytes: 65.7" "Cancer enriched" "Detected in single" 35 "testis cancer: 7.1" "Region enhanced" "Detected in many" "cerebellum: 4.7" "Immune cell enhanced" "Detected in some" "basophil: 3.7;neutrophil: 3.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BEWO: 18.4;CACO-2: 31.0;SuSa: 35.5" HPA006539 Supported Approved "Plasma membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 74: Testis - Spermatogenesis" "Cluster 39: CACO-2 - Unknown function" "Cluster 66: Spermatocytes - Spermatogenesis" "Plasma membrane" "HPA006539: AB_1078984" "unprognostic (2.52e-1)" "unprognostic (4.74e-3)" "unprognostic (1.79e-1)" "unprognostic (1.29e-1)" "unprognostic (3.35e-2)" "unprognostic (1.82e-3)" "unprognostic (8.62e-2)" "unprognostic (7.15e-2)" "unprognostic (1.89e-1)" "unprognostic (9.91e-3)" "unprognostic (1.23e-1)" "unprognostic (1.27e-1)" "unprognostic (8.46e-4)" "unprognostic (3.92e-2)" "unprognostic (3.41e-1)" "unprognostic (3.26e-2)" "unprognostic (1.22e-2)" 0.8 5.7 0.7 0.3 0.9 6.2 0.9 4.7 1.0 0.2 1.8 0.9 0.2 0.2 0.2 1.5 0.4 0.9 0.7 1.5 0.9 0.6 3.0 0.5 0.5 0.2 0.1 2.7 6.6 0.0 0.4 1.1 0.5 1.2 0.5 1.4 0.1 0.1 0.5 0.7 0.5 0.5 0.0 0.3 0.2 81.3 1.3 0.2 0.2 0.1 0.2 1.0 0.3 0.5 0.4 1.5 0.7 0.4 0.3 0.8 18.4 0.2 0.0 0.0 0.5 31.0 0.2 0.1 0.8 0.0 0.3 0.2 0.1 0.0 0.0 0.7 0.2 3.3 1.2 8.1 0.1 2.0 4.5 0.0 0.2 0.2 0.0 0.1 0.0 1.1 3.6 0.8 0.0 0.7 0.4 1.6 3.6 0.1 0.0 0.2 0.1 1.1 0.0 0.5 0.6 0.2 0.5 0.7 0.1 35.5 0.1 2.7 0.5 0.1 3.0 0.5 0.5 3.0 1.3 0.6 0.9 0.1 0.6 3.7 0.4 1.0 0.6 0.1 0.6 0.3 0.5 0.4 0.2 0.3 0.3 0.4 3.4 0.6 0.1 0.2 1.0 0.2 0.7 0.9 4.7 1.0 1.5 0.9 0.2 0.1 0.5 0.0 1.3 0.5 2.1 0.0 1.1 0.0 0.9 0.6 0.0 0.0 0.0 0.1 0.1 0.3 2.4 0.0 0.0 0.0 4.2 0.4 0.5 0.1 0.0 0.0 8.9 0.1 1.3 3.2 0.0 6.9 1.9 1.5 1.5 1.9 0.0 0.2 9.5 6.4 5.3 0.5 0.2 0.0 2.2 0.0 0.0 2.5 12.2 5.4 0.3 1.4 1.8 1.9 0.0 0.1 0.0 0.5 0.4 0.3 5.7 2.6 0.1 0.0 0.1 0.0 0.0 0.5 0.0 0.2 2.7 65.7 3.1 0.0 0.1 0.4 3.6 4.2 0.1 0.0 SLC2A5 GLUT5 ENSG00000142583 "Solute carrier family 2 member 5" P22732 1 9035106-9088478 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 97.3;intestine: 109.1;skeletal muscle: 78.8;testis: 76.4" "Cell type enhanced" "Detected in many" "Early spermatids: 64.3;Paneth cells: 55.6;Plasma cells: 35.3;Proximal enterocytes: 189.4;Spermatocytes: 83.2" "Group enriched" "Detected in many" 6 "glioma: 11.0;renal cancer: 11.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "naive B-cell: 23.3" "Lineage enriched" "Detected in many" 5 "B-cells: 23.3" "Group enriched" "Detected in some" 5 "Daudi: 190.3;THP-1: 47.8;U-266/70: 154.0;U-698: 178.2;U-937: 68.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA005449, HPA075145" Enhanced Enhanced "Plasma membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" "HPA005449: AB_1078985, HPA075145: " "unprognostic (1.53e-1)" "unprognostic (1.23e-1)" "unprognostic (8.00e-3)" "unprognostic (2.25e-2)" "unprognostic (6.13e-2)" "unprognostic (2.61e-1)" "unprognostic (1.47e-2)" "unprognostic (5.35e-2)" "unprognostic (4.18e-1)" "unprognostic (6.85e-2)" "unprognostic (3.77e-2)" "unprognostic (1.18e-1)" "prognostic unfavorable (5.44e-5)" "unprognostic (8.56e-2)" "unprognostic (2.07e-1)" "unprognostic (8.19e-3)" "unprognostic (8.61e-2)" 7.7 3.4 9.2 5.4 9.2 97.3 5.1 10.5 11.8 2.6 10.1 4.8 109.1 1.3 10.5 3.9 2.6 1.1 2.3 10.3 12.0 38.4 0.6 1.2 20.4 24.1 14.5 2.8 0.6 1.5 2.9 4.9 20.4 15.1 3.6 2.7 2.4 5.1 78.8 6.9 85.3 4.4 14.3 5.6 0.9 76.4 16.1 1.7 0.8 65.9 18.3 3.0 4.2 19.6 0.3 0.1 0.0 0.2 0.2 1.2 0.5 0.2 0.7 0.0 0.6 1.3 0.0 190.3 0.2 0.4 0.1 0.4 1.7 0.1 0.4 25.1 0.2 0.2 3.4 0.0 0.3 3.0 1.6 2.7 2.6 0.6 0.0 2.9 0.0 0.1 0.3 2.0 0.0 0.0 0.1 10.0 0.2 0.0 0.2 4.9 0.0 5.9 0.2 2.0 0.6 0.3 0.3 0.5 0.7 0.1 0.3 47.8 0.2 3.0 0.9 0.5 0.2 154.0 0.2 178.2 0.2 68.2 0.2 4.8 2.5 0.2 0.2 0.5 0.2 4.3 0.2 0.2 0.9 23.3 0.2 0.2 1.4 0.3 0.1 0.2 0.1 1.2 9.2 9.2 10.5 11.8 10.3 12.0 24.1 14.5 20.4 14.3 16.1 19.6 0.3 0.0 0.0 2.0 5.2 2.0 2.0 0.2 10.2 0.0 0.1 0.4 1.9 0.0 0.0 1.8 0.0 0.1 0.0 1.4 7.9 0.3 64.3 0.1 0.3 4.9 1.2 0.0 1.0 0.0 1.1 0.8 0.0 0.4 1.3 0.1 0.4 0.1 4.3 0.0 1.2 7.6 0.0 0.8 1.2 19.3 2.8 2.7 0.0 31.9 0.6 0.6 0.0 2.5 0.9 0.6 55.6 0.4 35.3 2.1 189.4 24.2 0.0 0.1 6.6 2.1 0.4 83.2 8.2 2.7 0.6 0.5 0.3 0.3 8.0 0.2 SLC35C2 "bA394O2.1, C20orf5, CGI-15, OVCOV1" ENSG00000080189 "Solute carrier family 35 member C2" Q9NQQ7 20 46345980-46364458 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027011 Approved Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" "Golgi apparatus" Nucleoplasm "HPA027011: AB_2672082" "unprognostic (7.25e-2)" "unprognostic (1.78e-1)" "unprognostic (1.01e-1)" "unprognostic (2.27e-2)" "unprognostic (1.06e-2)" "unprognostic (2.90e-1)" "prognostic unfavorable (1.08e-4)" "unprognostic (1.34e-1)" "unprognostic (1.23e-1)" "unprognostic (2.56e-1)" "unprognostic (4.05e-2)" "unprognostic (1.29e-2)" "prognostic unfavorable (8.68e-4)" "unprognostic (9.31e-2)" "unprognostic (7.15e-2)" "unprognostic (1.18e-2)" "unprognostic (3.88e-1)" 23.2 36.3 23.1 17.2 22.3 27.1 23.2 21.3 25.2 26.4 22.6 23.9 21.3 23.1 17.4 31.8 23.2 18.2 17.2 21.8 20.6 27.7 38.3 22.8 24.0 22.6 23.1 25.5 34.9 14.9 20.3 18.2 22.3 31.2 10.1 11.3 30.3 14.0 18.3 32.7 26.4 10.4 21.2 33.6 27.7 25.0 23.4 14.4 29.2 8.2 13.4 22.4 25.6 22.8 35.9 45.1 17.5 15.0 23.9 23.2 36.3 17.6 33.7 19.7 22.6 60.9 54.6 22.5 63.2 19.9 24.7 49.0 9.3 40.5 6.7 19.6 32.5 20.2 29.5 49.0 46.6 27.6 23.6 33.6 51.0 27.4 29.8 20.8 15.2 23.7 33.3 41.5 14.2 85.0 19.8 40.7 24.3 34.1 36.7 18.9 19.7 45.3 25.8 35.1 28.1 39.6 16.4 87.1 60.9 10.4 56.0 47.8 15.7 53.2 33.7 27.5 32.0 55.6 51.5 25.2 58.0 29.7 23.9 42.7 37.9 48.0 37.5 39.9 35.4 29.7 39.0 38.8 42.4 27.9 44.5 40.3 33.5 33.4 30.8 72.9 41.1 44.1 23.1 22.3 21.3 25.2 21.8 20.6 22.6 23.1 22.3 21.2 23.4 22.8 17.0 16.0 19.1 24.5 27.6 14.4 29.0 35.5 29.0 41.3 32.4 25.4 6.7 21.5 29.2 27.6 41.7 89.5 32.6 26.9 13.7 41.3 5.9 12.8 13.0 18.4 21.0 12.4 13.6 61.8 49.2 24.0 26.0 13.9 14.7 20.3 31.8 27.5 38.7 18.5 13.6 35.1 26.4 22.8 8.2 6.7 19.3 23.6 21.4 14.0 36.4 23.4 34.0 11.1 14.2 35.0 26.9 19.2 28.8 50.0 34.8 18.3 18.7 33.6 19.7 20.1 19.0 16.1 23.6 24.8 16.6 79.2 25.9 24.8 30.2 33.1 SLC35G1 "C10orf60, FLJ33990, TMEM20" ENSG00000176273 "Solute carrier family 35 member G1" Q2M3R5 10 93893973-93956062 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "intestine: 68.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 26.9;Peritubular cells: 36.5;Proximal enterocytes: 47.4;Theca cells: 59.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 56: Intestine - Transmembrane transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "unprognostic (1.94e-2)" "unprognostic (1.90e-1)" "unprognostic (9.48e-2)" "unprognostic (1.65e-1)" "unprognostic (7.90e-4)" "unprognostic (8.89e-2)" "unprognostic (9.01e-3)" "unprognostic (1.15e-2)" "unprognostic (9.47e-2)" "unprognostic (7.90e-2)" "unprognostic (2.09e-1)" "unprognostic (4.30e-2)" "unprognostic (1.65e-2)" "unprognostic (2.29e-3)" "unprognostic (3.28e-1)" "unprognostic (3.02e-1)" "unprognostic (2.30e-1)" 0.8 0.8 0.1 1.0 0.1 0.3 0.7 0.2 0.1 0.4 1.0 6.0 68.4 0.8 0.8 1.1 0.4 0.6 1.4 0.1 0.2 0.5 3.7 0.8 0.8 0.3 0.2 1.0 9.5 2.1 1.1 0.8 0.4 0.7 5.8 0.2 1.4 0.8 0.6 1.5 33.4 0.9 0.1 0.6 2.0 3.4 0.2 0.4 1.4 0.2 0.6 1.1 0.7 0.1 6.2 6.1 2.9 3.3 0.9 2.5 3.8 5.4 6.2 5.2 6.5 4.8 4.2 3.9 2.1 3.6 3.4 11.1 6.7 2.1 7.9 4.8 7.0 3.2 3.7 3.6 1.3 6.1 6.1 2.4 2.1 3.9 2.3 1.7 2.3 3.5 3.0 2.2 3.1 2.2 2.9 1.3 3.7 2.2 7.1 0.0 4.6 1.5 2.5 5.3 3.7 3.4 7.2 3.5 4.6 2.4 3.7 2.0 2.9 3.8 6.1 6.8 5.6 2.5 2.4 1.3 2.8 0.0 2.7 0.0 0.1 0.7 0.1 0.1 0.4 0.1 0.8 0.5 0.1 0.1 0.8 0.5 0.0 0.0 0.0 0.1 1.1 0.2 0.1 0.1 0.2 0.1 0.1 0.2 0.3 0.2 0.4 0.1 0.2 0.1 3.2 3.2 3.9 1.0 2.4 3.1 2.1 2.2 2.2 4.3 1.5 2.7 4.7 5.7 1.6 7.3 4.2 3.0 0.6 26.9 3.9 2.3 20.3 1.8 5.0 4.7 4.2 3.0 2.6 9.7 6.1 4.4 3.1 1.3 0.0 19.9 5.0 5.8 2.3 1.7 6.4 5.0 2.0 3.3 1.2 9.2 17.1 0.9 5.4 1.0 3.1 4.8 0.0 5.0 0.9 3.1 18.3 36.5 2.2 1.3 47.4 1.2 1.3 2.7 0.0 3.6 2.4 19.1 9.2 4.1 1.8 0.8 3.6 59.2 8.3 2.3 SLC35G6 "AMAC1L3, TMEM21B" ENSG00000259224 "Solute carrier family 35 member G6" P0C7Q6 17 7481332-7483496 "Predicted membrane proteins, Transporters" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 9 "testis: 5.1" "Cell type enriched" "Detected in some" 5 "Early spermatids: 31.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 29: Early spermatids - Spermatogenesis" "unprognostic (3.81e-2)" "unprognostic (5.10e-2)" "unprognostic (2.05e-2)" "unprognostic (1.79e-1)" "unprognostic (1.65e-1)" "unprognostic (3.11e-3)" "unprognostic (1.37e-2)" "unprognostic (1.65e-3)" "unprognostic (3.29e-1)" "unprognostic (9.19e-3)" "unprognostic (1.69e-1)" "unprognostic (1.61e-1)" "unprognostic (3.13e-1)" "unprognostic (5.21e-2)" "unprognostic (3.79e-2)" "unprognostic (2.01e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.6 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 1.6 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 SLC38A8 ENSG00000166558 "Solute carrier family 38 member 8" A6NNN8 16 84009667-84042795 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Ion transport, Sodium transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 5 "brain: 3.9" "Cell type enriched" "Detected in some" 4 "Late spermatids: 16.1" "Cancer enriched" "Detected in single" 14 "melanoma: 6.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SCLC-21H: 2.5" "Low region specificity" "Detected in single" "Not detected" "Not detected" NA NA "Cluster 65: Brain - Ion transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (9.69e-2)" "unprognostic (6.16e-2)" "unprognostic (8.00e-3)" "unprognostic (6.40e-2)" "unprognostic (1.03e-1)" "unprognostic (8.20e-3)" "unprognostic (1.89e-1)" "unprognostic (7.70e-2)" "unprognostic (2.59e-1)" "unprognostic (2.16e-2)" "unprognostic (3.54e-2)" "unprognostic (1.37e-1)" "unprognostic (1.45e-1)" 0.0 0.1 3.7 0.0 3.9 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.7 1.0 0.8 0.0 0.1 0.0 0.0 1.1 1.6 0.0 0.2 0.1 0.7 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.3 0.4 3.0 0.5 0.0 0.1 0.0 0.0 0.0 1.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 3.9 0.0 1.3 1.0 0.8 1.1 1.6 0.9 0.6 3.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.2 0.0 0.1 0.0 0.0 0.6 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.0 1.4 0.0 0.0 0.0 0.0 16.1 0.6 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.2 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.7 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SLC39A13 FLJ25785 ENSG00000165915 "Solute carrier family 39 member 13" Q96H72 11 47407132-47416496 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 13 "Early spermatids: 298.2;Late spermatids: 905.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043971 Approved NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "HPA043971: AB_10959744" "unprognostic (7.84e-2)" "unprognostic (1.02e-2)" "prognostic unfavorable (2.60e-4)" "unprognostic (1.18e-1)" "unprognostic (8.56e-3)" "unprognostic (3.81e-2)" "unprognostic (7.44e-3)" "unprognostic (1.36e-1)" "unprognostic (5.40e-2)" "prognostic unfavorable (2.73e-5)" "unprognostic (1.39e-2)" "unprognostic (2.04e-2)" "prognostic favorable (1.96e-4)" "unprognostic (3.16e-1)" "unprognostic (1.73e-1)" "unprognostic (8.61e-2)" "unprognostic (4.12e-1)" 40.9 42.4 28.3 24.2 31.4 8.3 37.5 30.6 36.3 51.1 30.4 53.4 14.0 77.9 8.8 21.8 48.1 20.2 59.5 26.0 27.3 80.4 26.7 61.4 18.2 33.0 29.7 50.9 42.3 27.2 51.3 40.6 30.4 52.7 6.8 11.0 31.3 26.2 31.4 32.4 31.8 26.6 26.8 36.5 41.2 73.4 35.0 12.3 46.8 12.6 8.7 45.6 37.4 28.5 23.3 20.4 23.5 26.7 56.3 78.2 6.8 89.7 66.2 50.4 57.0 8.1 15.7 8.8 22.9 69.6 49.6 38.3 7.1 61.7 13.9 25.7 25.9 4.7 52.7 16.7 84.3 8.1 11.0 65.4 43.4 31.9 26.1 62.9 53.4 16.9 4.5 19.6 54.8 20.7 17.4 11.5 11.0 19.8 28.2 20.6 33.6 8.9 86.1 11.1 19.9 37.0 26.9 49.1 26.2 8.7 32.8 11.7 76.0 76.6 34.6 88.1 42.7 14.9 5.2 4.1 85.2 11.2 57.3 2.1 3.6 3.2 12.4 13.3 8.5 4.1 8.2 8.9 4.6 5.1 7.5 6.4 6.6 7.4 15.3 4.9 4.5 5.9 28.3 31.4 30.6 36.3 26.0 27.3 33.0 29.7 30.4 26.8 35.0 28.5 20.0 9.6 6.4 18.6 6.7 18.2 18.3 23.0 17.1 24.0 11.5 15.6 18.3 15.7 8.0 29.5 12.5 11.1 11.6 3.4 9.8 32.9 298.2 6.5 20.3 20.9 9.6 4.4 9.6 20.7 16.4 37.8 6.6 13.1 5.7 15.4 21.8 6.2 18.9 32.0 11.7 7.9 14.2 5.3 12.2 905.5 32.9 9.3 19.6 4.7 26.6 16.7 11.3 8.0 10.1 35.5 8.3 40.3 8.1 23.5 8.2 8.8 4.5 17.0 46.0 16.1 36.2 12.7 6.4 2.4 4.1 19.6 9.6 36.7 5.7 8.3 SLC3A2 "4F2, 4F2HC, 4T2HC, CD98, CD98HC, MDU1, NACAE" ENSG00000168003 "Solute carrier family 3 member 2" P08195 11 62856004-62888880 "Cancer-related genes, CD markers, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 780.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTCEpi: 1441.0;SiHa: 1287.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010455, HPA017980" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 170000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Plasma membrane" "CAB010455: AB_638288, HPA017980: AB_2669723" "unprognostic (1.79e-1)" "unprognostic (9.61e-3)" "unprognostic (3.59e-1)" "unprognostic (7.87e-3)" "unprognostic (2.06e-1)" "unprognostic (2.41e-3)" "prognostic unfavorable (8.17e-4)" "unprognostic (2.09e-3)" "unprognostic (2.62e-1)" "unprognostic (4.16e-2)" "unprognostic (2.29e-2)" "unprognostic (3.71e-1)" "prognostic favorable (8.22e-4)" "unprognostic (2.92e-2)" "unprognostic (5.52e-3)" "unprognostic (3.49e-3)" "prognostic unfavorable (1.48e-4)" 103.3 105.6 130.5 46.7 138.0 122.0 108.9 140.1 160.4 101.6 115.6 60.6 51.5 97.2 65.3 112.9 94.0 35.8 52.0 123.1 133.3 171.2 71.9 117.8 34.9 138.4 132.6 93.0 109.7 189.7 65.3 55.4 134.0 100.8 23.1 22.8 110.6 41.9 122.3 127.1 79.7 33.8 135.8 77.4 90.2 65.1 154.5 30.1 110.2 26.0 28.8 77.7 95.1 130.6 155.5 675.7 60.2 213.2 89.7 69.7 596.7 267.5 106.2 154.0 126.3 643.3 293.0 173.9 290.5 185.4 284.5 540.0 123.1 588.9 84.3 319.3 114.0 117.5 422.4 299.2 825.7 136.0 169.4 144.9 1441.0 175.3 528.8 46.2 83.6 380.7 232.9 347.4 95.1 792.6 149.8 181.3 106.9 222.5 214.2 153.8 92.7 341.8 113.9 84.0 112.5 53.5 1287.0 499.6 948.5 121.2 161.5 182.6 146.2 138.3 200.0 204.4 195.5 436.0 556.1 561.2 135.0 225.1 418.0 37.8 149.0 49.7 117.9 147.4 157.7 58.3 107.3 122.1 88.6 72.1 90.1 97.2 31.2 90.3 123.9 304.7 112.5 186.3 130.5 138.0 140.1 160.4 123.1 133.3 138.4 132.6 134.0 135.8 154.5 130.6 97.8 48.1 37.3 91.1 78.8 218.1 244.2 321.7 399.5 58.4 124.2 120.8 13.4 30.0 141.1 49.7 66.7 222.5 136.2 109.6 33.2 161.9 31.5 122.0 96.3 149.2 84.3 117.7 16.9 151.1 143.7 102.9 71.4 179.7 84.3 43.2 99.2 27.0 202.9 53.8 25.1 60.4 223.8 54.1 140.9 28.9 30.4 141.5 224.1 29.0 104.7 188.4 40.2 21.1 11.3 130.6 58.7 30.5 140.9 156.9 120.7 227.4 63.4 61.2 6.6 71.8 114.6 21.3 31.9 160.7 150.6 780.7 118.1 52.4 60.7 194.9 SLC41A3 FLJ20473 ENSG00000114544 "Solute carrier family 41 member 3" Q96GZ6 3 126006357-126101561 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045847 Approved Supported "Plasma membrane" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 80: Striated muscle - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA045847: AB_2679472" "unprognostic (1.77e-1)" "unprognostic (3.35e-2)" "unprognostic (1.11e-1)" "unprognostic (3.37e-2)" "unprognostic (7.68e-3)" "unprognostic (2.20e-1)" "prognostic unfavorable (1.49e-7)" "unprognostic (1.36e-1)" "unprognostic (3.23e-2)" "unprognostic (2.82e-3)" "unprognostic (5.74e-2)" "unprognostic (3.57e-1)" "prognostic favorable (6.04e-7)" "unprognostic (1.26e-1)" "unprognostic (5.88e-2)" "unprognostic (2.85e-1)" "unprognostic (7.54e-2)" 29.5 47.2 53.3 13.3 55.6 11.3 29.5 55.0 56.1 42.4 53.0 24.8 18.1 44.4 55.1 22.2 40.2 28.6 34.3 57.7 54.9 27.7 14.3 21.4 18.1 56.8 54.0 54.5 32.7 34.9 40.0 19.7 59.6 23.1 19.2 25.7 31.1 23.7 61.8 24.6 23.8 29.4 49.8 19.6 27.8 44.7 54.7 34.4 32.0 47.9 19.3 28.9 29.6 48.4 43.7 17.4 28.5 24.1 78.7 45.3 42.4 24.4 42.1 32.9 39.0 23.3 38.7 31.4 44.8 48.9 35.7 33.3 10.8 42.1 29.0 31.1 32.0 17.2 32.1 34.2 65.3 31.4 18.4 44.0 50.8 20.0 41.1 48.7 46.5 38.2 14.7 26.2 44.0 22.2 35.1 25.7 21.7 57.4 26.3 18.6 29.3 43.5 39.6 31.6 22.1 23.8 37.8 12.3 104.0 26.6 12.2 41.9 32.2 30.8 23.2 47.1 28.0 19.4 17.2 15.8 27.7 14.0 28.9 13.0 6.3 4.6 12.0 9.4 9.6 9.4 11.1 12.2 9.8 9.0 9.6 9.1 1.2 14.9 6.1 9.6 21.8 6.1 53.3 55.6 55.0 56.1 57.7 54.9 56.8 54.0 59.6 49.8 54.7 48.4 25.6 16.0 10.9 9.8 13.5 13.8 22.3 24.9 20.5 15.4 22.9 23.5 14.4 32.9 20.5 22.0 4.2 34.6 14.6 7.5 3.9 35.8 36.7 34.1 15.3 28.5 21.1 5.0 17.0 24.7 36.1 19.7 11.7 17.9 5.7 21.2 35.0 7.2 16.1 28.6 20.7 12.1 30.5 12.8 10.3 14.7 37.6 8.6 14.2 15.0 13.5 25.9 7.2 11.6 8.0 24.3 6.8 54.9 10.3 15.3 14.7 12.6 14.8 12.1 26.3 23.1 20.7 16.7 45.4 18.2 15.3 25.3 17.7 42.4 15.6 19.0 SLC46A2 "Ly110, TSCOT" ENSG00000119457 "Solute carrier family 46 member 2" Q9BY10 9 112878920-112890876 "Predicted membrane proteins, Transporters" Transport "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "cervix: 16.5;lung: 10.4;lymphoid tissue: 16.0;skin 1: 24.1" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 39.8;Endometrial ciliated cells: 15.8;Glandular and luminal cells: 6.9;Kupffer cells: 11.8;monocytes: 12.4" "Cancer enhanced" "Detected in some" "lung cancer: 1.4" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "classical monocyte: 24.6;intermediate monocyte: 12.1" "Lineage enriched" "Detected in many" 5 "monocytes: 24.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA020098 Approved NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 31: Skin - Epidermis development" "Cluster 11: Alveolar cells - Smell perception" "HPA020098: AB_2670363" "unprognostic (1.26e-1)" "unprognostic (5.15e-3)" "unprognostic (1.10e-2)" "unprognostic (1.53e-3)" "unprognostic (3.57e-3)" "unprognostic (2.10e-2)" "unprognostic (4.56e-1)" "unprognostic (2.18e-1)" "unprognostic (8.10e-2)" "unprognostic (1.50e-3)" "unprognostic (3.50e-1)" "unprognostic (1.38e-1)" "unprognostic (1.77e-2)" "unprognostic (2.37e-1)" "unprognostic (2.71e-2)" "unprognostic (1.83e-1)" "unprognostic (7.82e-2)" 0.1 0.0 0.1 0.6 0.1 0.1 0.9 0.5 0.2 16.5 0.0 0.0 0.0 3.0 4.7 1.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 10.4 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.2 1.5 0.0 24.1 0.0 0.4 0.0 0.9 0.0 0.6 0.5 16.0 0.0 0.0 0.1 3.0 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.6 0.0 0.1 12.1 0.1 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.3 0.0 10.1 0.2 0.0 6.6 0.1 0.1 0.5 0.2 0.1 0.1 0.1 0.1 0.2 0.0 0.5 0.3 0.0 0.0 39.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.7 1.5 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 15.8 0.8 0.3 0.0 0.0 0.9 0.0 0.0 0.2 0.0 6.9 0.0 0.0 0.4 0.1 2.1 0.0 0.4 0.0 0.0 11.8 1.8 4.4 0.0 4.1 0.0 0.0 12.4 0.0 1.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 SLC5A3 "SMIT, SMIT1" ENSG00000198743 "Solute carrier family 5 member 3" P53794 21 34073578-34106260 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 96.0" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 129.1;Collecting duct cells: 138.0;Granulosa cells: 148.6" "Cancer enhanced" "Detected in all" "thyroid cancer: 22.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029791 Supported "Plasma membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane" "HPA029791: AB_10601892" "unprognostic (9.70e-2)" "unprognostic (4.99e-2)" "unprognostic (2.23e-1)" "unprognostic (7.57e-2)" "unprognostic (1.07e-1)" "unprognostic (4.54e-2)" "unprognostic (4.48e-3)" "unprognostic (1.63e-1)" "unprognostic (3.02e-2)" "unprognostic (2.55e-1)" "prognostic unfavorable (1.98e-5)" "unprognostic (1.30e-1)" "prognostic unfavorable (4.72e-4)" "unprognostic (1.82e-1)" "unprognostic (1.82e-1)" "unprognostic (2.21e-1)" "unprognostic (8.60e-2)" 6.9 5.9 8.6 4.5 9.2 1.9 6.6 5.7 11.4 3.7 96.0 4.5 2.6 6.8 5.2 3.1 4.8 2.5 2.4 10.7 17.0 29.0 5.9 3.9 4.9 9.3 9.9 3.9 1.9 3.2 4.1 10.6 9.2 2.9 5.2 5.6 2.8 3.5 2.5 6.7 3.7 2.9 8.2 2.4 3.9 6.2 20.3 3.9 25.2 2.6 4.8 3.8 3.4 9.2 10.5 9.3 19.0 13.4 15.5 12.7 9.1 11.8 35.7 7.2 10.9 15.5 22.5 16.9 9.3 24.0 13.5 5.3 23.3 6.7 12.2 17.7 6.0 17.5 9.0 5.2 4.1 7.6 7.1 6.1 17.0 19.7 7.8 22.0 4.4 13.7 17.6 3.9 18.7 7.1 8.1 6.1 9.6 4.0 9.0 8.1 3.4 7.7 28.1 14.5 9.9 4.6 24.5 6.4 5.6 11.3 3.9 8.0 4.2 14.0 10.7 27.1 4.8 20.1 18.5 12.4 28.2 10.9 9.6 0.0 0.2 0.0 0.6 0.2 0.5 0.1 0.3 0.4 0.2 0.1 0.4 0.6 0.1 0.2 0.1 0.5 0.1 0.1 8.6 9.2 5.7 11.4 10.7 17.0 9.3 9.9 9.2 8.2 20.3 9.2 18.8 16.0 10.2 0.0 33.3 0.0 46.5 0.0 129.1 33.8 37.4 34.9 11.4 10.0 13.0 138.0 20.9 27.4 43.0 39.1 21.5 4.0 9.0 38.7 59.9 16.4 49.3 17.0 0.0 5.5 19.7 42.3 18.3 42.5 41.3 148.6 5.0 20.7 15.2 37.0 0.0 69.3 0.0 14.4 0.0 7.2 6.5 41.0 0.0 0.0 23.3 6.7 16.5 0.0 0.0 7.6 49.7 20.7 54.1 88.4 16.3 9.4 8.7 20.9 13.1 15.4 33.7 14.8 18.5 39.7 0.0 28.2 48.3 14.0 36.3 69.5 SLC5A9 SGLT4 ENSG00000117834 "Solute carrier family 5 member 9" Q2M3M2 1 48222685-48248644 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "intestine: 43.3" "Group enriched" "Detected in some" 4 "Alveolar cells type 1: 22.4;Proximal enterocytes: 84.0" "Cancer enhanced" "Detected in many" "liver cancer: 4.1;renal cancer: 3.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "Hep G2: 15.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA050263 Approved "Actin filaments,Cytosol" NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 45: Enterocytes - Digestion" "Actin filaments" Cytosol "HPA050263: " "unprognostic (3.09e-3)" "unprognostic (1.89e-1)" "unprognostic (6.75e-2)" "unprognostic (5.66e-2)" "unprognostic (2.36e-1)" "unprognostic (1.35e-3)" "unprognostic (3.64e-2)" "unprognostic (4.59e-2)" "unprognostic (3.60e-2)" "unprognostic (1.59e-1)" "unprognostic (7.42e-2)" "unprognostic (1.97e-1)" "prognostic unfavorable (1.84e-5)" "unprognostic (4.56e-1)" "unprognostic (2.11e-1)" "unprognostic (4.30e-3)" "unprognostic (1.06e-2)" 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.2 0.8 43.3 0.1 1.2 0.2 0.1 2.5 0.0 0.0 0.0 3.8 7.8 3.0 0.0 0.2 0.2 0.0 3.9 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.8 0.1 1.1 42.0 0.0 0.0 0.0 0.5 0.5 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 15.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.2 0.2 0.1 0.0 0.2 0.3 0.2 22.4 1.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.5 2.8 0.0 0.0 0.0 0.0 0.0 3.1 1.9 0.5 6.3 0.5 0.1 0.1 0.0 0.0 0.3 0.2 0.0 0.3 0.0 0.5 4.5 0.0 0.7 4.4 0.1 0.0 0.2 2.9 0.0 1.3 0.0 11.0 0.3 0.3 0.0 1.9 0.1 0.0 0.0 7.5 2.9 0.1 1.7 0.4 0.0 0.0 84.0 4.1 0.0 0.0 0.0 0.2 0.1 0.6 0.3 0.0 0.0 0.0 0.1 0.0 3.0 0.0 SLC66A2 "FLJ22378, PQLC1" ENSG00000122490 "Solute carrier family 66 member 2" Q8N2U9 18 79902420-79951657 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 185.4" "Cell type enhanced" "Detected in some" "Adipocytes: 20.3;Cardiomyocytes: 10.8;Cytotrophoblasts: 14.3;dendritic cells: 9.6;Extravillous trophoblasts: 14.6;Hofbauer cells: 36.1;Syncytiotrophoblasts: 20.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051666 Uncertain Approved Nucleoplasm NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 32: U-937 - Innate immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "HPA051666: AB_2681567" "unprognostic (6.03e-2)" "unprognostic (1.51e-1)" "unprognostic (2.36e-1)" "unprognostic (6.45e-2)" "unprognostic (3.94e-2)" "unprognostic (2.07e-2)" "unprognostic (1.39e-1)" "unprognostic (2.47e-1)" "unprognostic (2.50e-1)" "unprognostic (4.58e-2)" "unprognostic (1.02e-2)" "unprognostic (4.34e-1)" "unprognostic (1.40e-3)" "unprognostic (2.00e-1)" "unprognostic (1.20e-1)" "unprognostic (1.79e-1)" "unprognostic (1.70e-2)" 57.1 24.4 32.1 14.4 30.4 38.3 53.4 25.3 40.0 30.3 33.5 38.0 9.7 27.4 5.6 46.5 27.0 14.5 32.4 37.0 26.9 49.0 185.4 37.4 18.1 34.5 31.2 21.6 33.8 11.5 23.8 10.3 31.9 32.2 7.5 7.2 38.9 9.9 83.9 55.5 24.5 8.5 29.1 34.4 25.6 77.0 34.3 12.3 68.4 25.9 8.9 26.3 34.2 29.2 34.8 11.7 11.9 23.0 26.0 16.6 16.0 22.4 15.1 17.6 16.6 15.6 18.5 14.6 8.5 20.4 10.3 34.8 16.2 23.8 4.7 44.3 23.8 18.2 16.7 42.6 30.9 44.2 44.5 18.6 23.2 16.2 6.2 9.0 15.3 15.8 6.9 11.6 9.2 26.6 22.1 47.6 3.9 4.7 31.5 38.7 12.4 24.6 12.0 24.4 34.8 15.7 16.9 21.3 25.6 3.1 12.7 48.0 19.4 26.8 27.2 14.3 17.2 5.8 10.0 18.8 20.5 53.2 12.1 0.3 1.7 2.0 0.6 1.7 0.4 0.8 0.7 0.3 1.9 0.6 0.9 1.1 1.2 1.0 1.6 3.5 0.8 0.8 32.1 30.4 25.3 40.0 37.0 26.9 34.5 31.2 31.9 29.1 34.3 29.2 20.3 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.8 0.0 0.0 0.0 0.0 14.3 9.6 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 14.6 4.6 0.0 0.0 0.0 0.0 0.0 0.0 36.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 20.8 2.0 0.0 0.0 0.0 SLC6A16 NTT5 ENSG00000063127 "Solute carrier family 6 member 16" Q9GZN6 19 49289638-49325215 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 94.2" "Group enriched" "Detected in many" 8 "Early spermatids: 125.9;Late spermatids: 46.8;Spermatocytes: 153.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AF22: 18.2;SuSa: 9.9" "Not detected" "Not detected" HPA076812 Supported "Golgi apparatus" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 12: NES - Nervous system development" "Cluster 66: Spermatocytes - Spermatogenesis" "Golgi apparatus" "HPA076812: AB_2686816" "unprognostic (1.98e-1)" "unprognostic (7.15e-3)" "unprognostic (6.39e-3)" "unprognostic (1.36e-1)" "unprognostic (1.29e-1)" "unprognostic (6.83e-3)" "unprognostic (7.89e-2)" "unprognostic (7.92e-2)" "unprognostic (1.77e-2)" "unprognostic (1.21e-1)" "unprognostic (2.55e-3)" "unprognostic (1.63e-1)" "unprognostic (3.23e-2)" "unprognostic (3.31e-1)" "unprognostic (2.10e-1)" "unprognostic (8.93e-2)" "unprognostic (4.18e-2)" 4.5 2.0 2.8 2.9 2.2 4.5 3.2 1.2 2.1 4.6 17.9 3.8 1.2 4.0 2.4 1.7 5.8 2.3 2.5 2.2 1.8 8.5 10.0 4.9 7.3 5.0 4.9 7.0 6.9 0.9 1.6 3.2 4.3 5.0 1.1 5.0 1.5 2.9 1.0 2.2 3.7 1.8 2.9 4.7 3.5 94.2 2.5 2.3 3.2 0.5 5.5 3.6 3.4 2.1 0.0 7.3 18.2 6.5 0.3 2.8 3.3 0.9 1.5 0.6 2.0 0.2 0.6 8.5 1.1 0.8 0.3 0.3 2.0 0.3 2.2 1.3 2.1 0.7 0.7 1.7 1.4 0.6 3.0 2.8 1.1 1.4 1.0 5.2 1.6 1.5 1.7 1.1 2.4 1.6 0.5 0.3 6.4 0.3 0.9 0.3 4.4 1.6 1.0 0.0 0.2 0.4 2.9 0.1 0.6 9.9 2.9 0.3 9.3 1.4 6.7 4.2 0.0 4.0 4.6 7.5 0.1 2.0 0.4 0.2 0.3 2.6 1.6 1.2 1.5 4.5 0.5 1.6 0.4 2.2 1.4 0.9 1.9 1.8 2.1 1.1 0.9 1.3 2.8 2.2 1.2 2.1 2.2 1.8 5.0 4.9 4.3 2.9 2.5 2.1 4.4 0.0 1.1 3.6 5.8 1.5 0.9 0.4 2.2 8.6 1.7 1.7 1.5 2.8 0.1 1.8 2.1 0.0 1.7 0.1 11.7 0.8 125.9 2.3 1.6 3.9 0.0 0.0 4.1 0.6 0.0 1.7 0.0 1.5 1.3 0.3 2.2 5.5 0.9 0.0 8.1 0.1 0.0 1.4 1.8 46.8 3.7 0.8 5.4 12.2 1.2 0.5 5.2 2.5 1.7 0.2 0.0 3.4 1.5 0.5 0.0 0.3 11.3 1.2 0.0 1.7 4.9 153.5 8.3 0.3 1.3 0.0 1.1 1.8 0.1 0.3 SLC6A5 "GLYT2, NET1" ENSG00000165970 "Solute carrier family 6 member 5" Q9Y345 11 20599594-20659285 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 23 "brain: 22.2" "Group enriched" "Detected in some" 39 "Early spermatids: 20.6;Late spermatids: 66.9" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "medulla oblongata: 22.2;pons: 20.0;spinal cord: 7.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in some" 9 "pons and medulla: 49.3" "Group enriched" "Detected in many" 8 "medulla oblongata: 30.5;spinal cord: 18.3" CAB079052 Supported NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 31: Spermatids - Spermatogenesis" "CAB079052: " "unprognostic (6.94e-2)" "unprognostic (2.28e-1)" "unprognostic (4.75e-2)" 0.0 0.0 1.2 0.0 0.0 0.0 0.0 1.3 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.9 0.0 22.2 1.3 0.0 0.0 0.0 0.6 0.0 20.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 1.3 0.2 0.2 0.0 22.2 1.3 20.0 7.6 0.1 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 66.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SLC6A8 "CRTR, CT1" ENSG00000130821 "Solute carrier family 6 member 8" P48029 X 153687926-153696588 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Disease variant, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 142.0;Distal enterocytes: 382.0;Proximal enterocytes: 235.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 155.8;AN3-CA: 151.3;SK-BR-3: 156.8" "Low region specificity" "Detected in all" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (5.80e-2)" "unprognostic (1.24e-1)" "unprognostic (2.39e-2)" "unprognostic (9.98e-2)" "unprognostic (1.47e-1)" "unprognostic (7.16e-2)" "unprognostic (1.59e-2)" "unprognostic (1.59e-2)" "unprognostic (2.08e-1)" "unprognostic (2.10e-1)" "unprognostic (1.21e-1)" "unprognostic (1.43e-1)" "prognostic unfavorable (1.53e-4)" "unprognostic (1.41e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (7.39e-4)" "unprognostic (2.87e-1)" 31.6 66.6 77.2 9.0 99.4 34.5 23.9 77.8 80.0 17.5 39.9 73.5 51.3 32.4 13.0 54.6 17.3 31.3 130.4 76.8 82.1 81.4 4.5 9.2 1.9 89.0 90.5 12.4 20.0 45.6 21.4 36.2 76.9 31.3 30.5 34.7 52.3 35.9 166.6 45.9 75.9 20.7 71.3 13.1 30.8 38.5 87.6 11.9 8.2 75.5 3.0 41.2 36.5 116.6 155.8 6.7 39.5 151.3 14.7 9.9 10.2 22.2 37.7 28.7 35.5 20.1 2.1 0.2 17.0 27.9 33.6 54.3 85.3 78.0 17.0 2.7 83.3 0.6 50.6 59.7 50.0 1.2 10.1 20.9 16.5 27.3 103.3 50.7 14.9 0.9 37.3 2.4 15.7 9.3 0.8 3.6 47.0 30.9 67.0 7.6 5.2 2.1 30.8 29.5 56.0 64.2 33.8 156.8 107.9 9.8 30.9 23.9 14.1 45.2 73.1 58.2 66.5 5.2 3.0 1.8 105.5 4.5 47.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 77.2 99.4 77.8 80.0 76.8 82.1 89.0 90.5 76.9 71.3 87.6 116.6 5.9 0.0 1.9 14.0 2.7 23.2 14.3 91.1 13.1 142.0 19.6 18.4 106.9 21.5 55.6 5.5 110.5 15.3 2.8 382.0 3.9 4.6 1.5 21.4 38.9 6.5 25.9 23.4 8.2 22.2 37.7 8.8 6.1 16.1 4.5 14.4 3.9 0.9 4.9 119.5 9.9 44.2 38.7 1.9 5.7 3.7 9.0 4.1 24.9 2.8 3.2 19.0 0.0 9.0 23.7 47.5 101.1 8.2 0.8 28.3 235.8 53.3 31.3 49.3 32.9 15.6 19.0 2.9 3.9 16.9 15.6 90.8 2.9 1.5 20.7 18.6 SLC7A4 "CAT-4, HCAT3, VH" ENSG00000099960 "Solute carrier family 7 member 4" O43246 22 21028718-21032840 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 15.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 21.2;Endometrial ciliated cells: 16.4;Glandular and luminal cells: 32.0;Intestinal goblet cells: 8.9;Ionocytes: 12.2;Syncytiotrophoblasts: 10.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 21 "BEWO: 140.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA031023 Enhanced NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 28: BEWO - Transcription regulation" "Cluster 44: Endometrium - Transcription" "HPA031023: AB_10669669" "unprognostic (1.02e-3)" "unprognostic (4.34e-2)" "unprognostic (6.75e-2)" "unprognostic (1.27e-1)" "unprognostic (3.82e-2)" "unprognostic (1.04e-2)" "unprognostic (1.58e-1)" "unprognostic (3.91e-2)" "unprognostic (3.68e-2)" "unprognostic (2.51e-2)" "unprognostic (2.58e-2)" "unprognostic (1.21e-3)" "unprognostic (9.69e-2)" "unprognostic (2.87e-1)" "unprognostic (1.62e-1)" "unprognostic (1.32e-2)" "unprognostic (4.00e-3)" 2.7 2.6 3.1 0.2 2.6 0.0 1.0 3.8 2.8 1.5 4.5 1.1 1.0 1.0 0.3 5.6 1.1 1.3 1.1 2.3 3.8 0.4 0.3 0.8 0.3 1.8 2.6 0.3 0.2 0.5 4.7 3.3 4.5 2.5 0.9 0.3 2.2 3.2 0.4 1.6 1.2 0.3 0.3 0.5 1.4 15.4 4.8 0.3 0.0 0.0 0.5 1.1 0.6 0.7 0.0 0.0 0.0 0.1 0.0 0.0 140.5 0.0 0.0 0.3 0.1 1.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 6.5 0.0 0.0 0.1 0.0 0.6 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 1.6 0.0 0.0 0.0 1.3 0.5 0.3 0.0 0.1 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.2 3.1 2.6 3.8 2.8 2.3 3.8 1.8 2.6 4.5 0.3 4.8 0.7 0.0 6.4 1.9 0.3 0.0 0.0 0.3 7.4 0.6 0.5 0.7 0.6 0.3 1.5 3.1 0.0 0.0 21.2 0.0 0.5 0.0 0.0 0.3 16.4 2.1 0.3 1.2 0.0 1.4 0.4 7.7 2.0 1.1 32.0 4.5 0.7 1.1 0.0 1.4 0.0 0.8 8.9 12.2 0.0 0.0 1.8 1.8 0.1 0.0 1.0 0.0 2.0 0.0 0.0 0.1 0.8 0.3 0.7 0.0 0.5 0.3 0.0 2.6 0.1 0.0 0.3 0.4 0.3 1.5 1.8 0.0 10.1 0.7 0.0 0.6 0.6 SLC9A2 NHE2 ENSG00000115616 "Solute carrier family 9 member A2" Q9UBY0 2 102619553-102711355 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 20.7;stomach 1: 26.4" "Cell type enhanced" "Detected in some" "Distal enterocytes: 41.3;Early spermatids: 46.5;Gastric mucus-secreting cells: 41.8;Intestinal goblet cells: 23.4;Late spermatids: 31.4;Paneth cells: 38.7;Undifferentiated cells: 29.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 10.0;OE19: 37.3;RT4: 16.9;SK-BR-3: 14.7;T-47d: 18.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA035121, HPA035122" Approved Supported "Cell Junctions" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Cell Junctions" "HPA035121: AB_10602894, HPA035122: AB_2674477" "unprognostic (1.53e-2)" "unprognostic (8.05e-3)" "unprognostic (6.00e-2)" "unprognostic (3.00e-3)" "unprognostic (3.12e-1)" "unprognostic (1.09e-1)" "unprognostic (2.12e-1)" "unprognostic (1.86e-1)" "unprognostic (1.55e-1)" "unprognostic (1.23e-1)" "unprognostic (2.37e-2)" "unprognostic (1.97e-1)" "unprognostic (1.40e-3)" "unprognostic (1.60e-1)" "unprognostic (7.51e-2)" "unprognostic (1.39e-2)" "unprognostic (1.70e-1)" 0.0 0.1 1.4 2.1 0.7 0.0 1.4 0.8 1.5 1.4 0.2 20.0 6.3 0.1 3.9 0.3 0.3 1.1 0.0 1.9 0.9 5.4 0.0 0.1 0.1 1.4 0.7 0.0 0.0 5.8 1.0 0.0 1.5 5.8 20.7 0.1 4.9 2.1 6.4 0.8 3.4 0.7 0.8 0.0 26.4 5.7 1.2 0.4 1.0 6.2 4.5 1.0 0.0 0.5 10.0 6.1 0.0 1.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.7 0.2 0.0 3.4 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.3 3.4 2.9 0.0 0.0 0.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 7.7 0.0 0.1 0.2 37.3 5.0 0.0 0.1 0.0 1.1 16.9 0.1 0.0 0.0 14.7 0.0 0.0 18.5 0.0 0.0 0.0 0.7 0.0 1.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.7 0.8 1.5 1.9 0.9 1.4 0.7 1.5 0.8 1.2 0.5 0.0 0.0 0.0 2.0 0.3 0.4 0.2 0.1 0.0 0.0 1.1 0.1 0.8 0.0 0.3 9.2 0.0 0.5 0.0 41.3 0.0 0.2 46.5 0.5 0.2 0.3 9.7 0.0 3.0 0.0 0.0 0.0 41.8 3.1 0.0 0.0 0.0 0.0 0.1 0.0 14.6 23.4 6.1 0.0 0.4 31.4 0.6 0.0 0.0 5.6 0.0 0.5 0.0 1.0 1.0 8.5 38.7 0.0 0.2 4.1 3.2 1.4 0.1 0.1 0.0 0.5 0.1 4.5 0.2 0.0 0.6 0.3 0.2 0.0 29.6 0.8 SLCO6A1 "CT48, MGC26949, OATP6A1, OATPY" ENSG00000205359 "Solute carrier organic anion transporter family member 6A1" Q86UG4 5 102371774-102499016 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 109 "testis: 30.2" "Group enriched" "Detected in some" 5 "Early spermatids: 168.8;Spermatocytes: 127.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA054126 Enhanced NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA054126: AB_2682390" "unprognostic (1.17e-1)" "unprognostic (2.59e-1)" "unprognostic (4.37e-2)" "unprognostic (4.65e-1)" "unprognostic (1.84e-1)" "unprognostic (2.60e-2)" "unprognostic (6.70e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 168.8 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 26.0 1.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 127.7 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SLFNL1 FLJ23878 ENSG00000171790 "Schlafen like 1" Q499Z3 1 41015597-41023237 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 18 "testis: 76.0" "Group enriched" "Detected in some" 76 "Early spermatids: 217.4;Late spermatids: 668.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 5.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA054956 Approved Cytosol NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 39: CACO-2 - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "HPA054956: AB_2682649" "unprognostic (7.01e-3)" "unprognostic (1.62e-1)" "unprognostic (1.54e-3)" "unprognostic (4.35e-2)" "unprognostic (3.39e-1)" "unprognostic (4.11e-4)" "unprognostic (8.98e-3)" "unprognostic (1.02e-3)" "unprognostic (8.40e-3)" "unprognostic (1.50e-1)" "unprognostic (2.51e-1)" "unprognostic (3.71e-4)" "unprognostic (2.70e-3)" "unprognostic (1.10e-1)" "unprognostic (2.09e-1)" "unprognostic (3.26e-1)" "unprognostic (2.43e-1)" 0.3 0.3 1.1 0.2 1.1 0.5 0.2 1.4 1.6 1.2 2.8 1.0 0.3 1.0 0.0 0.3 1.1 0.2 0.4 1.0 1.1 0.7 1.6 2.0 0.3 1.0 0.8 1.3 0.7 0.0 0.9 0.1 0.9 1.4 0.0 0.6 4.2 0.1 0.3 0.3 1.1 0.0 0.7 0.4 0.4 76.0 0.9 0.0 0.7 0.0 0.0 0.7 0.6 0.9 0.5 0.8 0.4 0.6 0.0 0.1 2.5 1.1 0.0 0.0 0.0 5.4 0.5 0.9 0.9 0.0 0.2 0.9 0.0 0.0 0.0 0.7 1.5 0.7 1.5 0.7 0.3 1.0 0.6 0.1 0.1 0.0 0.0 0.2 0.1 0.8 0.6 1.1 0.0 0.4 0.6 1.1 0.9 0.1 1.3 1.3 0.6 0.6 0.0 1.4 0.6 0.3 0.2 0.5 0.4 0.4 0.3 0.6 0.4 1.0 1.2 0.5 0.8 0.6 0.3 1.1 0.1 1.1 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.1 1.4 1.6 1.0 1.1 1.0 0.8 0.9 0.7 0.9 0.9 0.1 0.0 5.1 0.3 0.0 0.3 0.1 0.0 0.0 0.7 0.3 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 217.4 0.1 0.2 0.2 0.0 0.0 2.2 0.2 0.0 0.2 0.0 0.3 0.0 0.2 0.0 0.0 0.1 0.0 2.6 0.0 0.0 0.0 0.3 668.9 3.4 0.2 0.0 0.0 0.0 0.0 0.0 0.5 2.4 0.0 0.0 2.2 0.0 0.2 0.1 0.2 0.0 0.1 0.0 0.1 0.0 5.8 2.3 0.0 0.1 0.0 0.1 0.1 0.1 0.0 SMAD7 "MADH7, MADH8" ENSG00000101665 "SMAD family member 7" O15105 18 48919853-48952052 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 54.5;Distal enterocytes: 56.6;Hepatic stellate cells: 71.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 4.1;eosinophil: 5.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 38.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026212, HPA028897" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Cytosol" "CAB026212: , HPA028897: AB_10600811" "unprognostic (1.63e-1)" "unprognostic (3.72e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (5.61e-4)" "unprognostic (8.15e-2)" "unprognostic (5.35e-1)" "unprognostic (2.76e-1)" "unprognostic (6.02e-2)" "unprognostic (2.37e-1)" "unprognostic (1.87e-2)" "unprognostic (2.70e-1)" "unprognostic (2.09e-1)" "unprognostic (1.91e-1)" "unprognostic (1.56e-1)" "unprognostic (1.31e-1)" "unprognostic (1.50e-2)" "unprognostic (4.44e-1)" 17.9 5.9 7.1 8.6 7.3 17.8 14.5 12.0 7.3 17.4 9.6 12.7 10.3 11.2 2.9 4.8 8.2 10.2 46.1 5.4 5.1 11.6 8.6 21.9 5.8 10.9 8.7 7.5 5.3 12.3 6.6 18.9 8.5 11.3 11.9 3.2 6.3 8.6 10.7 8.3 15.0 9.3 10.0 5.9 12.5 1.3 7.9 3.7 16.6 6.7 5.2 13.3 12.2 8.4 3.7 2.8 2.8 8.3 14.3 5.0 21.1 18.6 7.1 6.5 3.1 1.0 5.3 0.3 32.2 13.1 6.0 19.2 6.1 5.8 3.6 38.4 9.4 0.3 10.5 6.9 2.1 6.9 18.6 5.1 4.8 7.8 7.8 32.2 1.1 0.6 6.6 25.9 9.1 1.2 0.0 1.9 17.3 27.7 1.1 2.1 2.5 9.0 9.1 4.2 4.8 10.3 8.0 3.5 6.6 21.2 3.3 5.6 17.3 18.5 9.9 5.3 16.5 13.4 7.1 2.0 8.1 4.9 3.1 4.1 0.1 5.6 0.8 0.5 0.6 0.1 0.8 0.7 0.1 0.0 0.2 0.5 0.0 1.7 0.1 0.0 1.2 0.2 7.1 7.3 12.0 7.3 5.4 5.1 10.9 8.7 8.5 10.0 7.9 8.4 30.4 54.5 9.4 3.9 7.0 12.9 3.5 7.2 14.2 6.1 14.7 10.3 9.7 1.5 11.2 11.0 6.2 9.9 43.7 56.6 9.8 14.4 0.2 43.2 30.5 25.0 12.7 0.0 6.5 13.9 3.3 15.5 8.2 45.9 18.9 4.0 71.4 3.1 8.9 0.0 5.0 19.1 2.0 23.3 8.9 1.1 1.5 14.7 0.0 19.7 8.2 1.4 11.3 5.5 16.3 31.5 17.3 3.4 13.8 3.0 28.7 7.1 3.3 2.5 6.6 11.3 14.1 0.1 0.6 14.2 11.8 12.9 25.2 1.3 12.4 2.6 SMC4 "CAP-C, hCAP-C, SMC4L1" ENSG00000113810 "Structural maintenance of chromosomes 4" Q9NTJ3 3 160399274-160434954 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA condensation, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 60.6" "Cell type enhanced" "Detected in many" "Erythroid cells: 305.8;Spermatocytes: 339.8;Spermatogonia: 239.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "basophil: 74.4" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029449, CAB055509" Approved Supported "Nuclear speckles,Cytosol" NA Yes 25000 "Cluster 18: Basophils - Vesicular transport" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear speckles, Cytosol" "CAB055509: , HPA029449: AB_10603891" "unprognostic (2.63e-1)" "unprognostic (1.01e-1)" "unprognostic (2.45e-2)" "prognostic unfavorable (7.63e-4)" "unprognostic (2.22e-1)" "unprognostic (1.28e-2)" "prognostic unfavorable (2.94e-4)" "unprognostic (9.54e-2)" "unprognostic (2.18e-2)" "unprognostic (5.47e-2)" "prognostic unfavorable (4.20e-5)" "prognostic unfavorable (9.00e-4)" "prognostic unfavorable (8.05e-7)" "unprognostic (3.03e-2)" "unprognostic (4.46e-1)" "unprognostic (1.06e-1)" "unprognostic (4.98e-2)" 6.8 6.5 1.0 21.2 2.0 36.3 6.8 1.2 1.7 6.3 1.5 13.2 14.0 7.4 2.3 23.5 4.5 7.6 7.3 0.9 1.9 5.9 7.8 11.8 37.1 1.7 1.4 5.9 7.8 3.8 2.0 16.2 1.6 5.8 14.9 7.7 4.6 5.0 3.6 11.0 15.4 10.1 1.3 14.7 11.8 32.5 1.9 60.6 9.0 6.8 31.6 9.6 4.3 3.2 386.3 72.8 155.0 73.0 31.5 30.9 72.1 181.2 88.8 206.0 176.8 94.4 209.7 236.6 101.9 81.1 140.0 212.5 183.0 95.0 332.4 297.9 113.8 234.7 123.3 33.6 17.3 158.3 182.6 14.6 13.3 114.4 96.5 78.5 94.8 103.2 130.3 272.2 133.9 78.3 183.2 44.4 91.8 106.7 149.3 180.1 238.8 177.3 43.4 54.8 93.7 94.0 141.4 135.1 65.5 76.6 156.9 128.6 84.8 132.2 105.2 119.9 349.8 181.1 192.2 412.0 96.7 166.9 151.9 74.4 6.0 23.6 11.5 8.9 11.4 17.2 18.2 14.3 6.6 15.0 11.4 10.2 10.8 15.3 15.9 11.7 30.3 9.5 1.0 2.0 1.2 1.7 0.9 1.9 1.7 1.4 1.6 1.3 1.9 3.2 24.6 105.8 174.0 3.9 43.7 40.8 18.2 33.1 30.7 14.9 21.5 21.0 41.3 25.8 35.0 35.0 8.4 74.6 54.4 41.4 3.9 20.9 48.6 35.2 27.0 44.8 30.1 305.8 3.5 14.7 138.1 50.7 32.6 36.1 79.1 77.3 38.2 20.4 61.3 0.0 2.9 44.5 24.4 29.7 43.5 28.3 25.1 36.4 17.8 17.8 39.3 9.3 46.4 3.5 30.1 13.5 26.5 48.2 95.9 14.1 25.9 8.6 25.4 25.8 131.5 21.7 73.2 339.8 239.4 58.1 35.7 34.1 58.4 34.6 69.7 19.1 SMDT1 "C22orf32, DDDD, dJ186O1.1, EMRE" ENSG00000183172 "Single-pass membrane protein with aspartate rich tail 1" Q9H4I9 22 42079691-42084284 "Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032117, HPA060340" Uncertain Supported Nucleoplasm,Mitochondria NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Nucleoplasm "HPA032117: AB_10601093, HPA060340: AB_2684257" "unprognostic (1.11e-2)" "unprognostic (1.46e-3)" "unprognostic (5.77e-2)" "prognostic favorable (5.32e-8)" "unprognostic (1.25e-1)" "unprognostic (2.40e-1)" "unprognostic (1.03e-1)" "unprognostic (2.07e-2)" "unprognostic (2.55e-1)" "unprognostic (4.84e-2)" "prognostic favorable (5.87e-4)" "unprognostic (2.96e-1)" "prognostic favorable (2.36e-9)" "unprognostic (1.91e-1)" "unprognostic (2.65e-1)" "unprognostic (1.45e-1)" "unprognostic (9.72e-3)" 12.2 13.9 21.6 6.1 22.2 17.6 19.5 25.7 27.7 14.6 21.2 14.7 10.3 12.3 19.5 12.6 15.2 7.4 20.0 22.1 22.0 18.2 15.1 9.7 16.1 21.6 21.4 22.5 21.5 18.0 14.9 7.3 22.2 16.1 11.2 16.0 22.7 13.4 35.6 14.8 13.5 8.4 21.3 12.6 17.7 6.9 21.3 12.4 18.6 37.9 12.2 12.4 11.9 22.4 5.7 3.7 7.4 8.9 13.1 9.5 5.8 2.0 10.0 12.1 10.5 7.1 5.3 7.8 2.4 10.3 3.4 6.1 9.8 10.4 7.7 3.8 15.7 4.7 8.1 10.3 16.5 8.6 5.9 7.4 17.3 4.8 9.9 6.9 12.2 5.1 7.9 12.3 8.4 11.2 12.1 13.0 2.8 14.1 2.7 10.8 6.5 20.8 15.5 6.4 9.2 6.0 5.0 11.1 12.8 3.7 9.3 9.3 4.8 5.1 5.3 4.5 3.9 8.2 9.8 16.9 7.9 8.5 4.1 4.0 5.8 2.9 3.1 3.1 5.9 5.9 8.6 4.5 8.4 7.2 9.3 6.0 0.5 5.5 4.5 6.4 5.4 5.4 21.6 22.2 25.7 27.7 22.1 22.0 21.6 21.4 22.2 21.3 21.3 22.4 161.1 83.3 109.3 11.8 295.0 166.7 202.2 157.3 191.2 71.6 400.9 477.3 350.9 237.4 160.3 204.1 20.9 308.7 127.8 285.6 573.2 160.0 114.0 156.8 81.1 138.2 345.2 135.7 10.5 199.6 190.6 127.8 150.3 127.2 91.4 55.4 161.3 380.1 256.1 55.5 12.8 356.5 262.4 164.5 200.6 131.9 189.2 187.7 211.7 5.6 125.8 196.4 124.6 7.5 13.8 193.7 314.0 149.0 275.8 238.2 486.7 623.4 223.7 109.5 124.9 133.6 202.7 256.0 55.5 271.5 274.1 308.8 186.3 151.7 308.8 272.2 SMIM10L2B "LINC00087, NCRNA00087, RP11-85L21.2" ENSG00000196972 "Small integral membrane protein 10 like 2B" P0DMW5 X 135094985-135098712 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 29.5" "Cell type enhanced" "Detected in some" "Bipolar cells: 4.1;Cardiomyocytes: 4.8;Horizontal cells: 11.8;Muller glia cells: 5.0;Peritubular cells: 3.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 1.8;GAMG: 2.1;HHSteC: 1.8;HSkMC: 2.9;NTERA-2: 1.6" NA NA "Cluster 65: Brain - Ion transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 62: Horizontal cells - Visual perception" "unprognostic (2.60e-2)" "unprognostic (3.08e-1)" "unprognostic (3.16e-2)" "unprognostic (1.18e-3)" "unprognostic (7.25e-3)" "unprognostic (9.55e-2)" "unprognostic (5.90e-2)" "unprognostic (6.02e-2)" "unprognostic (4.54e-2)" "unprognostic (7.05e-2)" "unprognostic (4.69e-2)" "unprognostic (1.13e-2)" "prognostic favorable (2.41e-5)" "unprognostic (2.03e-3)" "unprognostic (1.94e-1)" "unprognostic (2.32e-2)" "unprognostic (4.98e-2)" 1.2 3.3 17.7 0.4 19.3 0.0 1.3 6.2 24.2 3.1 0.5 1.4 0.4 2.7 2.1 2.0 3.1 0.8 11.1 19.2 23.4 3.7 1.3 1.4 0.4 20.3 20.9 4.5 1.0 5.8 3.7 0.4 29.5 3.5 0.4 2.2 3.0 2.1 0.8 1.6 0.8 1.4 7.7 1.0 1.6 5.6 16.9 0.1 2.2 0.8 0.3 1.2 2.2 14.4 0.0 0.0 1.3 1.2 1.8 0.2 0.6 0.4 0.2 0.2 0.3 0.5 0.0 0.0 0.2 0.2 2.1 0.1 0.4 0.4 0.0 0.0 0.4 0.0 0.0 0.0 1.8 0.0 0.1 2.9 0.2 0.0 0.1 0.3 0.1 0.6 0.0 0.0 0.1 0.0 0.4 0.0 1.6 0.3 0.1 0.0 0.3 0.0 0.7 0.2 0.6 0.2 0.2 0.1 0.0 1.3 0.0 0.2 0.0 0.1 0.5 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.7 19.3 6.2 24.2 19.2 23.4 20.3 20.9 29.5 7.7 16.9 14.4 0.4 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 4.1 1.0 1.8 4.8 0.0 0.0 0.0 0.0 0.1 0.2 0.0 1.9 0.3 0.1 0.1 1.2 0.7 1.2 0.0 0.0 0.7 0.1 1.1 0.0 0.2 0.0 1.3 0.7 1.7 0.0 11.8 0.0 0.3 0.0 0.3 0.0 0.8 3.1 0.1 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.5 0.0 3.8 0.0 0.4 0.1 1.7 0.0 1.5 0.0 0.6 2.3 1.0 0.5 0.8 0.0 0.3 0.0 0.9 0.1 0.4 SMIM19 C8orf40 ENSG00000176209 "Small integral membrane protein 19" Q96E16 8 42541155-42555195 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011145, HPA074830" Uncertain Approved "Nuclear speckles" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 2: Karpas-707 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Nuclear speckles" "HPA011145: AB_1078360, HPA074830: " "unprognostic (2.12e-2)" "unprognostic (2.33e-3)" "unprognostic (4.01e-2)" "unprognostic (1.85e-2)" "unprognostic (1.42e-1)" "unprognostic (6.68e-3)" "unprognostic (7.04e-3)" "unprognostic (1.76e-2)" "unprognostic (4.84e-2)" "unprognostic (1.74e-1)" "unprognostic (2.40e-1)" "unprognostic (2.67e-2)" "prognostic favorable (1.74e-6)" "unprognostic (5.10e-2)" "unprognostic (9.70e-3)" "unprognostic (9.64e-2)" "unprognostic (2.93e-3)" 55.2 57.1 34.7 18.4 35.4 32.5 64.9 35.8 44.3 31.9 35.8 41.7 30.0 32.6 80.0 33.2 57.0 27.8 59.6 36.1 35.8 76.9 136.8 31.5 36.9 34.2 34.9 42.2 68.5 36.2 26.8 23.3 35.1 31.9 34.6 21.1 62.6 30.1 121.8 44.8 38.9 25.1 35.7 33.3 46.2 43.9 35.0 36.6 73.5 74.1 33.9 36.4 29.9 37.3 38.9 28.5 61.0 52.6 35.9 43.2 19.9 29.9 40.2 23.4 27.8 6.8 84.4 42.4 12.2 25.1 57.0 27.2 31.8 19.2 24.3 33.8 26.3 35.9 17.9 15.5 73.9 25.7 9.0 35.4 16.1 19.6 62.7 45.3 21.5 49.1 28.8 94.5 23.7 38.0 18.8 39.0 72.1 90.4 19.5 21.1 43.4 72.4 60.7 28.5 12.7 46.0 30.0 32.2 93.1 32.6 68.0 48.2 27.3 14.7 12.5 40.8 19.6 88.7 53.8 56.9 62.2 40.9 39.6 92.2 42.3 31.4 46.3 34.0 56.5 71.3 59.6 57.0 65.1 68.3 55.6 54.3 15.3 80.7 28.8 107.2 78.2 40.0 34.7 35.4 35.8 44.3 36.1 35.8 34.2 34.9 35.1 35.7 35.0 37.3 53.1 22.4 45.9 5.9 43.0 45.8 63.5 89.8 70.6 25.2 89.9 108.8 75.7 88.6 66.2 33.1 6.2 90.1 58.6 36.2 201.5 67.9 183.9 109.6 26.0 43.9 16.3 45.6 12.7 126.8 62.9 65.5 43.3 54.8 40.0 52.3 47.8 142.5 78.3 23.5 13.4 74.4 61.1 45.9 51.0 77.5 69.0 47.3 92.5 11.2 64.0 66.7 42.2 10.6 14.6 85.5 69.5 59.5 29.0 53.3 161.9 228.2 110.9 14.3 26.3 67.6 50.7 131.3 48.6 58.4 49.6 47.2 43.3 76.4 74.8 63.2 SMKR1 ENSG00000240204 "Small lysine rich protein 1" H3BMG3 7 129502531-129512918 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 19 "testis: 123.6" "Group enriched" "Detected in many" 50 "Early spermatids: 1894.5;Late spermatids: 6100.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "MCF7: 19.7;SCLC-21H: 32.8" "Low region specificity" "Detected in all" HPA078358 Approved Nucleoli NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 78: Testis - Spermatogenesis" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 25: Spermatids - Spermatogenesis" Nucleoli "HPA078358: AB_2686883" "unprognostic (5.08e-2)" "unprognostic (1.72e-1)" "unprognostic (1.64e-1)" "unprognostic (1.45e-1)" "unprognostic (1.57e-3)" "unprognostic (2.13e-1)" "unprognostic (6.45e-3)" "unprognostic (1.02e-1)" "unprognostic (9.24e-2)" "unprognostic (4.05e-2)" "unprognostic (2.00e-1)" "unprognostic (6.30e-2)" "unprognostic (1.72e-6)" "unprognostic (1.67e-2)" "unprognostic (1.11e-2)" "unprognostic (6.40e-2)" "unprognostic (3.67e-2)" 0.3 1.1 5.2 0.4 5.9 0.1 1.9 4.2 5.8 0.5 4.1 0.1 0.4 0.3 1.4 0.4 6.6 0.2 0.1 5.4 5.5 0.8 0.1 0.3 0.9 4.5 5.0 0.2 2.3 6.4 6.1 0.2 4.7 0.4 0.2 0.7 0.2 0.3 0.1 0.4 0.4 0.1 4.5 0.5 0.4 123.6 6.4 0.3 0.7 0.1 0.8 0.1 0.2 5.2 13.4 13.0 0.4 11.1 0.0 0.0 0.1 0.0 0.4 1.1 1.1 0.1 3.4 0.0 1.1 0.7 7.2 1.6 2.3 0.1 1.6 12.6 1.3 0.0 2.5 0.0 2.3 0.2 8.2 0.1 5.5 3.3 2.3 1.4 0.4 7.9 0.7 0.3 0.6 19.7 2.5 1.2 1.5 3.4 11.2 1.3 0.0 2.9 4.7 0.0 32.8 9.0 9.6 1.1 0.8 2.1 3.0 1.7 0.1 0.0 0.3 7.3 2.8 3.2 4.5 0.2 4.5 0.5 0.9 0.0 0.0 0.0 1.3 0.0 0.6 1.0 0.2 0.7 0.0 0.8 0.5 0.5 0.0 0.4 0.0 0.0 0.0 0.1 5.2 5.9 4.2 5.8 5.4 5.5 4.5 5.0 4.7 4.5 6.4 5.2 0.1 3.2 0.0 1.0 6.4 0.1 2.2 1.1 2.2 1.4 8.9 10.9 0.3 0.0 1.4 5.5 0.0 0.0 7.7 0.1 9.8 2.3 1894.5 21.1 0.3 1.9 9.0 0.4 2.9 6.2 0.3 1.0 1.5 0.9 0.0 2.1 0.7 0.0 0.1 0.0 2.3 0.0 4.1 0.3 0.4 6100.1 37.6 2.3 1.8 0.0 0.8 1.1 40.2 0.5 0.3 3.0 0.0 27.4 2.4 5.3 0.0 1.9 12.6 0.6 0.0 1.1 0.7 78.8 29.7 1.4 0.3 0.1 5.3 0.1 0.2 1.2 SMOC1 ENSG00000198732 "SPARC related modular calcium binding 1" Q9H4F8 14 69854131-70032366 "Disease related genes, Human disease related genes, Predicted secreted proteins" Differentiation "Developmental protein" "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 53.2;liver: 67.9" "Cell type enhanced" "Detected in many" "Hepatocytes: 104.4;Oligodendrocyte precursor cells: 372.4;Oligodendrocytes: 81.1;Peritubular cells: 133.2" "Cancer enhanced" "Detected in many" "glioma: 27.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 11 "plasmacytoid DC: 1.3" "Lineage enriched" "Detected in single" 14 "dendritic cells: 1.3" "Cell line enhanced" "Detected in some" "AF22: 50.3;HeLa: 122.6;HSkMC: 38.3;SiHa: 72.1;SK-BR-3: 30.6;U-266/70: 42.3;U-87 MG: 51.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004153, CAB034427" Approved Approved "Plasma membrane" "Secreted to extracellular matrix" NA NA 140000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 15: Liver - Metabolism" "Cluster 20: HeLa - Mitochondria" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane" "CAB034427: AB_2193382, HPA004153: AB_1080035" "unprognostic (3.31e-1)" "unprognostic (2.17e-3)" "unprognostic (8.17e-2)" "unprognostic (1.96e-2)" "unprognostic (1.89e-2)" "unprognostic (4.04e-1)" "unprognostic (6.75e-3)" "unprognostic (2.09e-3)" "unprognostic (4.76e-2)" "unprognostic (2.80e-2)" "unprognostic (5.10e-2)" "unprognostic (5.63e-2)" "unprognostic (4.09e-2)" "unprognostic (3.92e-1)" "unprognostic (2.57e-1)" "unprognostic (1.34e-1)" "unprognostic (1.87e-1)" 15.9 10.3 29.2 0.5 30.3 0.1 6.2 53.2 29.1 9.4 17.5 1.3 1.9 2.2 7.7 0.3 6.6 0.5 8.3 27.9 31.6 3.0 67.9 0.6 0.9 38.4 38.8 1.4 10.3 0.3 4.4 8.0 36.8 33.4 1.0 2.4 5.8 38.8 12.7 2.4 1.4 1.0 41.2 27.2 3.8 35.7 29.6 0.4 4.2 2.7 0.5 1.3 6.3 52.8 0.0 3.3 50.3 0.0 9.8 6.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.2 0.2 0.0 2.9 0.0 0.0 20.4 0.0 122.6 17.4 0.1 0.0 0.0 38.3 11.9 1.4 1.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.2 0.3 0.0 0.0 0.0 1.6 0.0 0.0 0.0 2.0 0.2 72.1 30.6 0.0 0.3 0.0 0.0 0.4 0.3 2.9 0.0 0.0 42.3 0.0 0.0 51.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 29.2 30.3 53.2 29.1 27.9 31.6 38.4 38.8 36.8 41.2 29.6 52.8 0.3 0.0 0.0 12.1 2.5 0.3 0.0 0.7 0.0 2.1 1.3 3.8 2.0 7.2 0.1 0.0 16.7 24.2 4.0 0.0 0.0 0.3 4.7 11.9 0.6 2.9 15.6 0.0 1.0 2.3 0.8 6.0 3.6 1.5 0.0 1.4 3.3 104.4 2.8 0.0 13.5 0.1 14.2 2.5 0.4 19.0 7.8 0.3 0.0 1.0 0.1 0.3 0.0 372.4 81.1 3.7 0.1 133.2 12.4 0.0 0.0 0.0 1.1 0.3 0.0 0.7 2.3 2.1 3.9 0.0 0.4 40.2 0.4 0.4 0.0 0.1 SMPD3 NSMASE2 ENSG00000103056 "Sphingomyelin phosphodiesterase 3" Q9NY59 16 68358327-68448508 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Lipid metabolism, Sphingolipid metabolism" "Developmental protein, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 61.5;lymphoid tissue: 52.0" "Cell type enhanced" "Detected in many" "dendritic cells: 77.1;Gastric mucus-secreting cells: 70.8;Horizontal cells: 301.2;Proximal enterocytes: 115.1" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "amygdala: 8.0;basal ganglia: 29.7;cerebral cortex: 24.9;hippocampal formation: 25.4" "Immune cell enriched" "Detected in many" 7 "plasmacytoid DC: 138.9" "Lineage enriched" "Detected in many" 7 "dendritic cells: 138.9" "Cell line enhanced" "Detected in some" "HMC-1: 9.7;MOLT-4: 14.7;RPMI-8226: 12.4;SCLC-21H: 13.4" "Region enhanced" "Detected in all" "basal ganglia: 115.2" "Region enhanced" "Detected in all" "basal ganglia: 67.7" "CAB033885, HPA065535, HPA069383" Approved Supported "Endoplasmic reticulum" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 56: Intestine - Transmembrane transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 62: Horizontal cells - Visual perception" "Endoplasmic reticulum" "CAB033885: AB_1126788, HPA065535: , HPA069383: " "unprognostic (1.21e-1)" "prognostic favorable (7.72e-4)" "unprognostic (5.61e-3)" "prognostic favorable (3.86e-4)" "unprognostic (2.46e-1)" "unprognostic (5.85e-4)" "unprognostic (7.87e-2)" "unprognostic (8.12e-3)" "unprognostic (2.77e-2)" "unprognostic (1.30e-1)" "unprognostic (1.75e-1)" "unprognostic (1.81e-1)" "unprognostic (1.04e-3)" "unprognostic (5.02e-3)" "unprognostic (2.49e-1)" "unprognostic (1.19e-1)" "unprognostic (1.93e-3)" 6.8 2.1 8.0 3.6 29.7 1.8 2.8 1.8 24.9 2.7 0.1 13.8 61.5 1.4 0.1 2.1 3.8 9.0 1.5 25.4 0.5 4.0 7.4 2.5 4.2 0.0 0.2 4.8 2.6 0.1 16.5 0.2 0.6 4.6 6.9 6.5 3.0 0.3 2.4 13.6 57.7 0.7 0.5 3.4 23.2 8.6 5.1 52.0 2.7 0.0 1.9 1.7 2.5 2.3 0.3 0.8 0.4 0.1 0.0 0.0 5.5 0.4 0.0 0.4 0.1 3.1 1.0 0.4 0.6 0.3 0.2 1.2 0.0 0.0 0.1 0.3 0.7 0.1 2.7 0.3 0.0 0.0 9.7 0.0 0.0 0.0 0.2 0.5 0.0 0.9 0.9 0.3 0.3 0.2 14.7 2.8 0.6 4.9 0.1 0.7 0.2 12.4 0.0 0.1 13.4 2.7 0.4 1.6 0.7 0.2 1.1 0.9 0.0 0.4 0.8 1.4 0.1 2.3 1.2 0.3 0.2 0.9 0.2 4.4 0.0 20.7 2.3 0.1 0.3 1.7 0.2 0.6 0.1 0.9 0.6 0.3 0.1 0.1 0.0 138.9 1.9 1.2 8.0 29.7 1.8 24.9 25.4 0.5 0.0 0.2 0.6 0.5 5.1 2.3 0.3 3.2 1.1 1.0 2.6 0.1 1.5 0.6 0.0 50.8 1.8 0.6 2.9 15.7 1.5 0.0 0.0 0.0 77.1 44.7 0.0 1.3 8.5 3.0 0.3 0.6 25.8 0.4 33.8 0.9 0.1 5.2 70.8 0.5 0.0 0.2 0.7 9.4 0.3 301.2 20.4 34.7 2.0 1.0 0.5 18.6 15.2 2.9 0.0 1.9 0.6 0.9 1.0 10.6 1.7 1.6 39.9 45.9 2.5 3.6 115.1 0.0 14.6 3.9 0.0 0.2 0.3 10.0 2.1 0.1 1.0 0.0 6.2 0.2 21.6 5.4 SMYD2 "HSKM-B, KMT3C, ZMYND14" ENSG00000143499 "SET and MYND domain containing 2" Q9NRG4 1 214281102-214337131 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "heart muscle: 198.8;skeletal muscle: 92.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 148.0;Cytotrophoblasts: 168.7;Early spermatids: 134.5;Extravillous trophoblasts: 110.5;Late spermatids: 120.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029023 Uncertain Approved Mitochondria,Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 38: Heart - Muscle contraction" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol Mitochondria "HPA029023: AB_10601605" "unprognostic (8.53e-2)" "prognostic unfavorable (1.53e-5)" "unprognostic (5.98e-2)" "unprognostic (1.00e-2)" "unprognostic (8.55e-2)" "unprognostic (2.53e-2)" "unprognostic (2.24e-2)" "unprognostic (1.72e-2)" "unprognostic (1.90e-3)" "unprognostic (1.65e-1)" "unprognostic (9.44e-2)" "unprognostic (2.77e-1)" "prognostic favorable (8.68e-4)" "unprognostic (2.65e-1)" "unprognostic (4.92e-2)" "unprognostic (8.10e-2)" "unprognostic (6.37e-2)" 15.5 15.0 12.4 9.0 13.0 8.9 18.7 13.5 32.1 12.2 17.8 12.9 13.8 9.5 7.5 18.1 27.6 9.3 198.8 14.6 16.1 20.4 26.2 18.1 13.5 14.7 16.7 12.0 19.1 6.9 17.1 27.3 14.2 12.1 14.3 14.3 13.7 8.1 92.4 11.4 12.6 10.1 14.5 15.1 19.2 24.3 14.4 22.6 20.3 4.2 14.2 11.8 10.1 14.4 64.4 14.5 22.7 16.8 21.7 37.7 102.4 36.6 28.8 41.8 46.6 68.3 52.0 34.6 36.7 39.8 19.7 28.9 21.3 63.5 36.8 28.3 29.8 10.1 30.0 46.7 19.9 47.6 7.4 42.9 31.2 30.5 21.6 27.2 32.1 29.5 35.0 7.5 36.4 33.5 32.6 26.1 21.3 32.4 26.3 20.6 59.9 27.8 33.9 45.2 23.7 55.3 28.9 95.0 73.3 47.8 75.5 30.1 38.6 32.9 49.6 18.0 55.2 33.2 13.0 39.2 43.1 35.1 37.8 15.8 10.0 14.4 15.0 5.7 17.8 15.4 22.5 19.9 9.5 7.5 19.3 18.0 0.9 29.2 1.9 6.4 26.7 13.0 12.4 13.0 13.5 32.1 14.6 16.1 14.7 16.7 14.2 14.5 14.4 14.4 10.5 19.2 9.7 7.5 13.7 20.6 16.5 40.0 25.0 8.7 16.8 19.9 148.0 24.3 17.7 3.7 0.0 168.7 12.2 10.0 31.3 34.3 134.5 48.7 9.9 15.6 4.2 8.6 60.7 20.0 110.5 11.1 11.7 17.4 3.8 27.9 17.2 20.3 38.4 15.2 26.9 13.4 14.2 21.5 10.6 120.4 11.8 11.4 16.0 22.5 11.7 28.1 9.2 7.1 10.3 26.1 11.7 3.8 16.4 16.1 21.9 34.6 69.6 8.0 13.1 6.8 16.7 13.9 39.6 28.9 18.0 85.9 16.8 30.0 19.3 10.9 SNAPC1 "PTFgamma, SNAP43" ENSG00000023608 "Small nuclear RNA activating complex polypeptide 1" Q16533 14 61762420-61796428 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 171.9;Spermatocytes: 215.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "GAMG: 153.7;hTERT-HME1: 153.7;U-2 OS: 207.6;U-251 MG: 146.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA067076, HPA072276" Enhanced Nucleoplasm,Nucleoli NA NA "Cluster 17: Basophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 9: U-2 OS - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoli Nucleoplasm "HPA067076: AB_2732757, HPA072276: AB_2732199" "unprognostic (7.40e-2)" "unprognostic (5.04e-2)" "unprognostic (3.09e-2)" "unprognostic (1.11e-1)" "unprognostic (2.94e-1)" "unprognostic (8.55e-2)" "unprognostic (1.68e-3)" "unprognostic (1.88e-1)" "unprognostic (4.01e-2)" "unprognostic (5.18e-2)" "unprognostic (1.58e-1)" "unprognostic (1.99e-1)" "unprognostic (2.47e-3)" "unprognostic (1.58e-1)" "unprognostic (1.07e-1)" "unprognostic (3.10e-1)" "unprognostic (2.26e-1)" 6.2 9.0 2.7 6.4 3.6 6.0 5.9 4.9 3.4 10.1 4.1 3.5 3.6 7.0 4.9 6.0 6.4 7.7 8.3 2.7 2.9 7.0 5.2 4.8 8.1 4.3 5.7 6.1 3.6 7.9 5.8 8.7 4.5 6.8 3.0 6.6 5.2 6.9 4.4 5.2 3.2 4.8 3.0 6.8 3.2 20.0 3.0 7.1 7.2 4.7 6.9 10.0 5.2 4.6 57.6 11.0 10.7 22.8 11.7 13.6 12.7 47.4 31.4 53.3 31.4 3.9 11.5 11.9 61.5 20.3 153.7 17.7 10.6 14.3 87.3 13.0 7.6 7.1 5.7 8.1 30.8 7.5 15.2 13.1 9.5 45.0 153.7 20.7 20.7 16.2 8.0 10.6 51.4 7.4 18.3 12.0 10.3 6.4 35.9 13.9 28.3 4.4 43.9 8.8 7.6 18.3 31.3 5.5 39.0 13.2 11.0 11.7 31.8 58.4 207.6 38.2 146.6 7.0 7.8 10.5 39.7 9.5 35.3 7.7 5.0 4.5 4.4 4.3 5.7 8.4 5.4 3.8 5.2 8.8 8.8 5.7 4.9 7.0 3.8 6.9 6.5 3.6 2.7 3.6 4.9 3.4 2.7 2.9 4.3 5.7 4.5 3.0 3.0 4.6 22.6 35.3 18.3 10.1 28.0 95.3 56.2 171.9 43.3 10.2 11.5 18.0 24.6 11.5 53.6 29.5 2.1 16.8 31.2 3.4 7.9 28.6 70.7 70.1 28.7 29.3 4.2 10.7 12.8 15.9 31.5 31.1 4.1 47.6 41.8 20.2 26.7 6.9 17.3 8.4 13.3 4.0 42.7 11.7 32.6 17.1 22.1 31.6 17.8 10.3 12.4 40.4 4.1 10.6 14.6 20.3 1.9 20.3 7.9 28.8 5.6 13.3 83.9 12.6 19.7 38.3 34.7 215.0 67.7 23.5 64.5 5.6 29.0 20.6 6.8 20.8 SNRPC "U1-C, Yhc1" ENSG00000124562 "Small nuclear ribonucleoprotein polypeptide C" P09234 6 34757505-34773857 "Plasma proteins, Predicted intracellular proteins" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 384.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034338, HPA042419, HPA055490" Supported Enhanced Nucleoplasm NA NA 320000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "CAB034338: AB_2295245, HPA042419: AB_2677989, HPA055490: AB_2682833" "unprognostic (1.84e-1)" "unprognostic (3.73e-2)" "unprognostic (1.59e-1)" "unprognostic (2.32e-3)" "unprognostic (1.45e-1)" "unprognostic (3.93e-2)" "prognostic unfavorable (5.65e-4)" "unprognostic (1.48e-2)" "unprognostic (6.16e-2)" "unprognostic (1.16e-3)" "unprognostic (7.71e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (8.20e-5)" "unprognostic (4.39e-2)" "unprognostic (8.64e-2)" "unprognostic (1.52e-1)" "unprognostic (2.62e-2)" 71.7 73.9 68.4 67.7 73.7 176.7 74.2 73.1 84.5 67.0 75.3 78.5 73.1 83.5 63.1 85.5 84.8 48.9 195.7 70.5 71.8 91.7 92.0 62.6 101.6 72.2 70.5 75.0 87.0 78.2 57.6 73.5 73.1 65.8 65.6 39.7 75.2 55.3 162.0 67.4 75.6 65.3 75.4 84.7 81.8 124.4 72.6 115.5 75.3 125.0 95.3 73.9 66.6 78.4 332.8 203.2 260.7 331.6 137.7 134.7 199.0 186.6 204.9 367.9 308.6 349.6 128.4 373.9 239.1 235.0 255.6 156.0 398.7 279.1 297.8 247.6 420.0 287.7 158.7 493.4 240.1 371.2 171.0 167.3 266.4 372.5 264.1 144.9 237.0 354.4 471.2 205.0 270.4 280.8 443.8 592.0 282.4 493.9 245.8 295.2 219.4 350.5 242.0 140.9 316.9 229.9 167.3 167.0 422.3 167.7 256.0 541.5 157.4 219.8 258.3 181.0 460.4 228.5 645.6 522.4 101.2 629.7 381.1 122.8 165.7 133.4 127.2 200.4 149.4 233.5 156.2 148.4 196.1 210.7 168.3 153.9 30.3 163.3 238.6 207.6 235.7 245.6 68.4 73.7 73.1 84.5 70.5 71.8 72.2 70.5 73.1 75.4 72.6 78.4 43.6 121.8 107.9 5.2 70.5 44.0 76.0 178.6 72.8 25.9 47.4 64.4 229.3 82.9 131.3 68.0 25.0 239.8 69.0 49.1 189.8 148.4 185.6 74.2 58.0 74.3 90.7 73.2 11.1 156.8 213.9 72.3 51.5 63.7 80.4 83.6 71.4 101.1 232.2 28.6 10.1 92.6 118.0 77.3 55.1 83.8 55.3 75.4 64.0 1.9 158.2 96.6 123.6 8.5 14.6 149.3 66.7 41.8 116.6 70.0 96.0 214.6 127.4 41.4 65.7 49.0 82.8 384.6 99.7 83.8 44.8 113.3 70.7 86.3 109.6 67.8 SNRPD2 "Sm-D2, SNRPD1" ENSG00000125743 "Small nuclear ribonucleoprotein D2 polypeptide" P62316 19 45687460-45692569 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" Ribonucleoprotein "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041437 Supported Supported Cytosol NA NA 76000 "Cluster 30: Non-specific - Translation" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 34: Spermatids - Unknown function" Cytosol "HPA041437: AB_10795119" "unprognostic (1.48e-1)" "unprognostic (1.11e-1)" "unprognostic (2.18e-1)" "unprognostic (1.94e-2)" "unprognostic (6.63e-2)" "unprognostic (6.84e-2)" "unprognostic (1.23e-3)" "unprognostic (2.08e-1)" "unprognostic (7.71e-2)" "unprognostic (3.50e-1)" "unprognostic (4.79e-2)" "unprognostic (1.78e-1)" "prognostic unfavorable (8.58e-5)" "unprognostic (1.95e-1)" "unprognostic (6.57e-3)" "unprognostic (1.53e-1)" "unprognostic (7.12e-2)" 201.0 215.1 305.0 237.7 317.2 478.3 390.9 309.5 374.8 267.3 297.8 253.3 170.1 228.8 331.5 244.5 318.1 195.9 265.5 312.2 321.0 215.6 200.1 157.1 442.7 312.2 308.3 440.0 184.9 263.5 202.9 215.3 310.8 201.9 253.5 120.8 197.4 209.7 306.0 245.1 168.1 235.2 311.1 202.2 189.1 167.5 315.5 501.0 214.7 305.6 406.4 312.2 216.4 312.6 970.0 1429.6 863.8 905.4 843.8 797.5 475.5 630.8 777.8 933.3 974.0 814.6 582.4 1119.3 493.9 788.2 624.9 543.7 1180.4 1184.6 888.6 721.6 1428.6 1066.5 756.6 1040.6 585.1 1287.9 646.4 894.2 862.7 798.3 759.9 639.5 960.3 1111.6 996.6 713.1 765.9 1329.7 1274.7 1129.0 780.8 1758.5 776.2 848.1 890.0 896.5 782.0 1249.4 792.7 880.4 828.1 842.8 808.7 705.9 500.2 1378.5 614.2 422.3 694.7 397.5 1198.8 717.5 1949.8 1775.2 601.5 1087.8 691.3 306.6 525.1 275.0 810.3 500.5 1045.6 1309.4 1076.4 964.5 789.1 1155.8 1244.5 1083.7 62.7 885.6 393.8 876.0 1144.9 1776.3 305.0 317.2 309.5 374.8 312.2 321.0 312.2 308.3 310.8 311.1 315.5 312.6 150.6 147.4 211.1 8.1 407.6 470.5 564.5 724.2 463.9 43.1 361.2 650.5 443.3 233.1 372.3 329.2 22.9 607.0 294.3 318.8 665.2 368.8 563.3 190.9 310.2 225.3 310.2 315.9 7.9 350.7 787.7 305.2 199.8 198.2 266.0 284.4 232.3 265.4 475.4 37.0 8.3 492.0 376.4 269.9 470.6 1325.8 347.9 232.5 434.0 9.4 373.9 162.6 373.9 3.5 12.2 318.2 348.5 231.7 341.2 553.5 356.9 768.7 309.3 65.2 164.3 279.4 382.1 286.3 274.7 562.6 422.7 482.8 426.5 216.2 556.9 534.0 SNTA1 "LQT12, SNT1, TACIP1" ENSG00000101400 "Syntrophin alpha 1" Q13424 20 33407957-33443763 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Disease variant, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 198.3;skeletal muscle: 307.9;tongue: 327.9" "Cell type enhanced" "Detected in many" "Astrocytes: 117.2;Cardiomyocytes: 175.1;Muller glia cells: 83.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 10.4" "Group enriched" "Detected in many" 4 "B-cells: 5.7;dendritic cells: 10.4" "Cell line enhanced" "Detected in many" "ASC diff: 66.5" "Low region specificity" "Detected in all" "CAB037059, HPA067154" Approved NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "CAB037059: AB_261497, HPA067154: " "unprognostic (2.25e-2)" "unprognostic (1.29e-2)" "unprognostic (1.02e-2)" "prognostic unfavorable (9.60e-6)" "unprognostic (5.68e-2)" "unprognostic (6.48e-2)" "unprognostic (1.38e-1)" "unprognostic (1.04e-2)" "prognostic favorable (7.08e-4)" "unprognostic (2.16e-1)" "prognostic favorable (3.72e-4)" "unprognostic (1.99e-1)" "unprognostic (8.09e-2)" "unprognostic (5.16e-2)" "unprognostic (1.48e-2)" "unprognostic (3.29e-2)" "unprognostic (7.60e-2)" 39.2 18.7 162.7 4.5 179.8 2.0 25.5 158.2 198.3 24.9 127.9 23.7 6.6 16.9 8.0 22.6 20.4 7.6 195.9 158.1 149.3 23.0 16.6 8.0 5.9 167.9 166.0 20.6 13.5 20.9 12.4 3.1 144.5 19.6 3.0 15.0 31.3 18.1 307.9 15.0 13.7 9.3 147.4 5.0 23.8 19.3 178.7 3.4 77.8 327.9 5.2 38.6 17.0 144.5 13.0 6.5 2.9 28.2 66.5 13.0 2.8 9.8 13.6 18.3 15.2 16.9 4.3 9.3 11.6 16.8 33.4 16.9 8.4 5.4 3.2 1.9 10.8 0.5 15.7 23.9 18.8 0.9 1.6 12.0 6.7 8.0 3.0 10.1 2.8 8.8 22.8 3.5 9.3 1.6 17.7 2.2 1.6 1.9 37.2 11.1 20.8 10.3 3.8 11.6 12.3 10.6 38.5 11.5 19.4 2.2 17.8 1.6 4.6 9.0 17.5 36.1 9.2 21.2 11.7 5.6 19.5 1.7 1.4 0.0 0.0 0.0 0.9 0.0 1.9 5.7 0.9 0.9 0.0 2.8 0.3 0.7 0.0 0.0 0.0 10.4 1.1 0.3 162.7 179.8 158.2 198.3 158.1 149.3 167.9 166.0 144.5 147.4 178.7 144.5 4.6 3.2 2.0 117.2 5.1 3.2 4.7 1.3 1.2 5.7 6.2 8.0 175.1 8.6 1.9 1.8 4.2 1.2 4.9 1.3 39.2 2.0 1.0 1.2 3.7 4.4 4.2 5.7 12.7 2.6 1.9 13.4 5.1 4.1 0.0 10.1 3.9 9.1 1.9 0.0 8.3 1.6 8.2 1.9 2.3 2.3 25.1 1.6 5.4 10.3 0.0 83.7 3.1 5.0 6.3 3.3 1.6 28.2 2.3 5.7 5.4 33.5 0.8 36.5 26.3 12.7 36.7 1.8 4.9 3.5 2.8 0.8 9.3 3.2 1.6 5.6 SNX13 "KIAA0713, RGS-PX1" ENSG00000071189 "Sorting nexin 13" Q9Y5W8 7 17790761-17940501 "Predicted membrane proteins" "Protein transport, Transport" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 274.3;Late spermatids: 211.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 43: THP-1 - Innate immune response" "Cluster 29: Early spermatids - Spermatogenesis" "unprognostic (7.26e-2)" "unprognostic (7.40e-2)" "unprognostic (3.03e-1)" "unprognostic (1.66e-1)" "unprognostic (9.02e-2)" "unprognostic (3.25e-1)" "unprognostic (2.52e-1)" "unprognostic (4.39e-1)" "unprognostic (1.23e-1)" "unprognostic (2.21e-1)" "unprognostic (7.85e-2)" "unprognostic (5.58e-2)" "prognostic favorable (5.98e-6)" "unprognostic (8.12e-2)" "unprognostic (6.96e-2)" "unprognostic (4.07e-1)" "unprognostic (1.46e-1)" 12.8 12.7 8.7 7.9 9.2 4.8 12.7 10.5 11.1 11.7 8.0 13.0 9.9 13.7 13.0 8.0 9.4 9.2 12.7 9.2 9.6 13.7 9.1 9.5 8.9 8.8 9.3 13.7 9.7 20.9 8.5 14.2 9.0 13.2 13.7 11.2 12.5 9.8 14.2 10.2 9.6 10.1 8.5 10.5 11.6 7.9 9.1 8.3 17.3 17.3 7.2 9.2 10.0 9.5 8.6 4.0 7.5 9.9 19.7 19.0 8.9 8.4 13.3 6.7 8.0 3.5 8.6 9.4 5.6 9.6 14.3 9.1 5.9 7.9 10.9 1.7 6.8 3.3 8.2 4.7 12.4 8.3 6.0 13.7 14.5 6.3 10.7 13.4 9.7 6.6 7.3 7.7 12.1 4.1 6.0 10.5 7.0 11.1 7.1 4.4 7.8 5.1 14.5 13.2 6.5 6.7 7.9 18.0 7.7 14.8 9.6 14.2 9.0 10.3 4.9 13.8 10.1 15.4 6.1 7.3 14.6 5.6 15.1 0.9 0.9 1.2 0.7 1.5 1.1 0.9 0.6 0.5 0.8 0.6 0.8 0.7 2.0 0.9 1.2 0.5 0.4 0.4 8.7 9.2 10.5 11.1 9.2 9.6 8.8 9.3 9.0 8.5 9.1 9.5 29.9 22.4 32.1 65.6 24.6 10.6 14.0 15.6 21.1 19.4 18.4 14.2 41.3 12.8 28.3 12.9 43.8 34.1 20.7 30.1 13.7 13.2 274.3 22.7 30.2 22.9 19.8 24.8 89.7 12.9 14.2 25.6 22.4 17.3 19.6 24.8 35.7 15.4 23.7 16.8 96.0 16.1 22.4 31.4 22.8 211.1 23.6 31.5 5.4 126.5 23.4 18.8 16.5 107.5 94.3 12.3 27.7 17.7 21.2 19.9 18.8 17.3 31.3 25.0 26.3 28.6 24.5 34.2 21.5 20.1 11.9 51.3 18.5 25.7 16.3 24.5 SNX20 "SLIC-1, SLIC1" ENSG00000167208 "Sorting nexin 20" Q7Z614 16 50666300-50681353 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 18.0;lymphoid tissue: 33.2" "Cell type enhanced" "Detected in some" "B-cells: 15.3;Cardiomyocytes: 16.4;dendritic cells: 23.7;Hofbauer cells: 17.6;Kupffer cells: 17.2;Langerhans cells: 25.2;Macrophages: 19.3;monocytes: 26.1;NK-cells: 24.7;T-cells: 21.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HDLM-2: 29.7;HMC-1: 78.5;NB-4: 48.0;RPMI-8226: 20.6;THP-1: 21.3;U-266/70: 25.7;U-937: 28.4" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA043649 Uncertain Uncertain Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 3: T-cells - Adaptive immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm "HPA043649: AB_10965697" "unprognostic (1.53e-2)" "prognostic favorable (9.07e-4)" "unprognostic (5.58e-2)" "unprognostic (5.06e-3)" "unprognostic (9.03e-2)" "prognostic favorable (6.56e-4)" "unprognostic (1.97e-1)" "unprognostic (1.26e-2)" "unprognostic (1.78e-2)" "unprognostic (1.04e-1)" "unprognostic (4.06e-2)" "unprognostic (1.84e-1)" "prognostic unfavorable (6.00e-6)" "unprognostic (3.24e-1)" "unprognostic (3.37e-2)" "unprognostic (1.53e-1)" "unprognostic (1.54e-1)" 2.3 1.0 1.5 20.0 1.5 18.0 1.1 1.8 1.7 1.1 1.5 2.7 2.9 1.0 0.6 1.6 1.0 4.0 0.8 1.3 1.8 0.8 2.2 7.7 27.8 3.4 2.1 0.6 0.5 0.4 0.5 2.7 2.5 1.1 3.6 0.3 1.9 0.7 0.8 2.4 6.1 2.7 2.1 19.2 3.7 0.5 2.6 33.2 0.9 1.1 27.0 6.1 0.7 2.9 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 29.7 0.0 5.2 0.0 0.0 0.0 7.4 78.5 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.2 0.0 0.0 0.0 48.0 0.0 0.0 0.0 2.4 0.2 20.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 21.3 0.2 0.0 0.0 0.1 0.0 25.7 14.3 6.5 0.0 28.4 0.0 306.6 66.9 208.0 41.6 118.3 52.2 22.6 73.8 50.9 123.4 22.6 56.1 38.9 62.3 51.3 147.5 34.3 137.5 81.8 1.5 1.5 1.8 1.7 1.3 1.8 3.4 2.1 2.5 2.1 2.6 2.9 0.2 0.0 0.0 0.3 15.3 0.8 0.0 0.0 0.0 0.2 0.3 0.6 16.4 2.8 1.3 0.0 0.0 0.1 23.7 0.0 0.0 0.0 0.1 0.3 0.1 1.5 0.0 6.5 0.0 0.0 0.2 0.5 0.5 0.1 5.1 0.0 1.1 0.4 17.6 1.7 0.0 0.0 0.0 17.2 25.2 0.0 0.0 19.3 0.0 0.0 26.1 0.1 24.7 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.1 0.0 0.1 13.1 0.5 0.5 0.2 0.1 0.0 0.6 0.4 21.3 0.1 0.2 0.0 SOBP FLJ10159 ENSG00000112320 "Sine oculis binding protein homolog" A7XYQ1 6 107490106-107661306 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 175.3;Excitatory neurons: 260.1;Granulosa cells: 149.3;Inhibitory neurons: 287.7;Oligodendrocyte precursor cells: 263.9;Oligodendrocytes: 278.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.3" "Lineage enriched" "Detected in single" 13 "B-cells: 1.3" "Cell line enhanced" "Detected in many" "AF22: 10.5;AN3-CA: 13.9;ASC diff: 12.9;HDLM-2: 9.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029242 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 47: Non-specific - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm Vesicles "HPA029242: AB_10603340" "unprognostic (7.11e-2)" "unprognostic (1.35e-3)" "unprognostic (9.01e-2)" "unprognostic (2.04e-3)" "unprognostic (3.09e-1)" "unprognostic (1.12e-1)" "unprognostic (3.80e-2)" "unprognostic (5.63e-2)" "unprognostic (9.84e-2)" "unprognostic (5.35e-3)" "prognostic favorable (1.55e-5)" "unprognostic (6.64e-2)" "unprognostic (2.00e-3)" "unprognostic (5.41e-2)" "unprognostic (2.12e-1)" "unprognostic (1.39e-1)" "unprognostic (1.95e-3)" 4.5 6.6 12.4 1.7 14.5 0.0 3.4 9.0 16.9 6.2 0.4 14.6 1.2 5.6 2.0 2.0 4.3 2.7 10.9 15.3 8.2 3.4 1.6 2.4 0.9 6.7 9.1 10.8 1.4 3.1 9.4 2.3 6.2 8.2 1.3 5.3 10.4 2.6 16.7 1.2 3.2 3.9 6.5 1.9 4.8 4.2 9.5 2.7 4.2 5.9 1.1 11.9 4.4 11.4 0.0 0.3 10.5 13.9 12.9 4.9 1.2 0.0 0.0 0.3 0.6 0.0 0.0 5.7 0.3 0.0 0.9 0.0 7.0 0.2 0.2 9.0 6.8 0.6 0.0 6.8 1.6 3.0 0.5 5.2 0.0 5.1 0.0 1.1 4.2 2.6 0.0 0.3 0.0 2.9 1.3 0.3 2.5 0.3 0.9 3.1 1.3 0.0 0.0 0.2 3.3 5.6 1.2 0.0 0.1 0.4 0.4 2.0 0.0 3.3 1.1 5.7 0.5 2.6 0.5 3.5 0.1 1.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 14.5 9.0 16.9 15.3 8.2 6.7 9.1 6.2 6.5 9.5 11.4 6.0 3.2 9.8 175.3 9.2 0.5 10.3 11.4 3.4 40.4 0.5 7.4 19.4 17.2 6.1 23.9 0.0 0.2 1.8 0.2 0.0 2.5 96.2 0.6 15.8 4.4 10.8 5.3 260.1 0.2 0.7 23.6 3.1 0.4 0.0 149.3 5.3 1.4 3.0 92.5 287.7 0.1 4.1 9.6 4.1 61.4 45.1 1.8 3.6 51.5 0.1 7.6 0.0 263.9 278.8 0.4 0.0 48.9 0.2 9.3 0.0 11.9 10.9 10.1 26.3 42.8 21.0 61.2 5.6 0.6 0.9 0.1 1.3 13.3 0.2 1.0 SOGA3 "C6orf174, dJ403A15.3" ENSG00000214338 "SOGA family member 3" Q5TF21 6 127472794-127519191 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.6" "Group enriched" "Detected in some" 9 "Excitatory neurons: 78.1;Inhibitory neurons: 57.4;Oligodendrocyte precursor cells: 44.2;Oligodendrocytes: 32.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 9.3;SCLC-21H: 28.9;SH-SY5Y: 16.9" "HPA035388, HPA035389" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Cytosol" "HPA035388: AB_2674601, HPA035389: AB_10669857" "unprognostic (1.70e-1)" "unprognostic (3.56e-2)" "unprognostic (1.57e-1)" "unprognostic (2.53e-2)" "unprognostic (1.19e-1)" "unprognostic (8.58e-3)" "unprognostic (8.45e-2)" "unprognostic (7.31e-4)" "unprognostic (5.65e-3)" "unprognostic (1.58e-1)" "unprognostic (3.33e-2)" "unprognostic (1.59e-1)" "unprognostic (3.30e-2)" "unprognostic (1.72e-1)" "unprognostic (8.26e-3)" 0.3 0.9 2.3 0.6 2.5 0.0 0.1 2.4 6.6 0.4 0.0 0.3 0.1 0.7 0.0 0.8 0.3 0.7 0.2 2.6 1.7 0.2 0.1 1.0 0.2 3.8 1.2 1.2 0.6 0.0 2.0 0.4 1.9 0.4 0.2 1.2 0.4 0.1 0.1 0.3 0.6 0.1 0.7 0.4 1.3 0.7 3.8 0.0 0.6 0.1 0.0 0.4 0.3 4.4 0.3 4.2 9.3 1.5 0.0 0.8 0.4 0.9 1.1 1.2 2.9 0.3 0.4 0.6 0.3 0.2 7.3 0.0 1.0 0.0 0.7 1.1 0.1 0.8 0.0 0.1 0.0 0.4 0.2 1.5 0.0 4.4 0.0 1.0 0.0 1.5 0.4 0.2 0.7 0.7 6.5 0.0 4.3 0.0 1.0 0.6 2.2 0.0 0.2 0.0 28.9 16.9 0.0 0.0 0.2 1.1 0.0 0.4 0.2 6.8 1.5 0.5 2.2 0.3 0.1 0.1 5.4 1.5 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.3 2.5 2.4 6.6 2.6 1.7 3.8 1.2 1.9 0.7 3.8 4.4 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 78.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 57.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.0 0.0 0.0 0.0 44.2 32.9 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 1.9 0.0 0.2 0.1 0.6 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 SORD ENSG00000140263 "Sorbitol dehydrogenase" Q00796 15 45023147-45077185 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 163.8;liver: 247.0" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 138.7;Hepatocytes: 649.4;Prostatic glandular cells: 218.8;Proximal tubular cells: 270.2" "Group enriched" "Detected in all" 4 "liver cancer: 30.3;prostate cancer: 72.5;thyroid cancer: 30.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 10 "basophil: 86.3;eosinophil: 55.9" "Lineage enriched" "Detected in all" 12 "granulocytes: 86.3" "Cell line enhanced" "Detected in many" "SK-BR-3: 57.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040260, HPA040621" Enhanced Approved Cytosol NA NA 2800000 "Cluster 52: Eosinophils - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA040260: AB_10794872, HPA040621: AB_10795384" "unprognostic (8.18e-2)" "unprognostic (7.58e-2)" "unprognostic (8.19e-2)" "unprognostic (1.51e-1)" "unprognostic (5.69e-3)" "unprognostic (3.90e-2)" "prognostic favorable (6.14e-5)" "unprognostic (3.33e-3)" "unprognostic (1.67e-1)" "unprognostic (4.95e-2)" "unprognostic (7.04e-3)" "unprognostic (1.40e-1)" "unprognostic (4.26e-2)" "unprognostic (1.23e-2)" "unprognostic (8.53e-2)" "unprognostic (2.31e-2)" "unprognostic (1.56e-1)" 2.0 15.7 4.9 3.1 3.8 2.8 53.8 7.4 8.4 163.8 1.9 5.3 7.5 4.3 6.9 10.2 6.7 8.2 5.6 5.0 4.5 50.3 247.0 3.2 2.6 4.3 3.7 2.4 5.7 4.4 3.1 2.5 4.0 87.9 7.8 4.8 5.3 27.0 2.2 16.6 7.2 3.5 4.2 2.3 9.2 12.2 3.9 3.7 89.4 2.8 3.4 9.1 6.9 6.3 12.3 12.2 4.7 20.8 4.4 5.3 5.9 1.8 3.5 12.2 7.0 12.2 5.8 2.7 8.0 5.4 4.1 17.6 19.9 19.1 9.2 29.9 12.3 13.5 12.1 50.3 0.2 18.0 25.5 6.7 18.0 6.6 9.5 5.4 12.5 15.1 11.7 10.6 14.9 8.1 18.4 38.3 39.0 29.4 13.8 0.9 16.6 6.4 16.8 12.1 25.1 12.2 2.1 57.3 5.9 5.2 16.4 22.5 4.7 3.5 38.0 1.6 5.8 8.7 4.5 4.4 14.2 18.6 10.6 86.3 1.7 55.9 1.6 1.5 1.7 5.4 1.3 1.6 1.7 6.9 1.6 1.4 3.8 1.1 2.1 2.4 2.5 2.0 4.9 3.8 7.4 8.4 5.0 4.5 4.3 3.7 4.0 4.2 3.9 6.3 3.9 0.0 3.1 5.5 11.9 7.8 26.5 14.8 17.6 10.8 24.7 17.5 3.2 25.8 28.1 33.1 0.0 1.3 2.3 15.0 29.4 68.2 31.7 40.2 17.4 4.9 84.8 37.5 4.8 138.7 5.1 7.5 31.1 43.7 8.8 11.5 15.7 649.4 16.0 3.3 5.4 32.5 22.4 24.2 6.4 24.1 3.7 12.2 16.0 1.0 13.3 9.0 2.1 7.1 8.9 89.0 18.1 6.0 7.9 218.8 8.0 270.2 42.5 4.7 0.0 8.9 8.9 7.4 2.8 35.1 20.3 1.0 6.5 15.3 39.4 131.2 SOS2 ENSG00000100485 "SOS Ras/Rho guanine nucleotide exchange factor 2" Q07890 14 50117130-50231578 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 8.0" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004577, HPA047368, HPA052689" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 8: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 44: Endometrium - Transcription" Nucleoplasm Vesicles "CAB004577: AB_628270, HPA047368: AB_2680014, HPA052689: AB_2681917" "unprognostic (7.99e-2)" "unprognostic (6.17e-2)" "unprognostic (7.80e-2)" "unprognostic (4.93e-2)" "unprognostic (2.81e-2)" "unprognostic (7.64e-2)" "unprognostic (1.56e-1)" "unprognostic (3.08e-1)" "unprognostic (2.01e-1)" "unprognostic (3.88e-1)" "unprognostic (9.99e-2)" "unprognostic (8.21e-2)" "prognostic favorable (8.48e-8)" "unprognostic (2.47e-2)" "unprognostic (1.91e-1)" "unprognostic (1.01e-1)" "unprognostic (6.57e-2)" 23.8 14.9 15.3 15.3 21.4 39.5 17.9 18.2 19.5 14.3 13.5 17.4 21.5 15.2 22.4 16.4 12.7 12.9 21.5 14.0 16.8 24.5 13.2 15.8 14.4 19.7 18.6 15.3 15.9 39.3 9.1 17.0 19.1 15.4 17.3 14.0 14.5 18.7 57.6 17.9 24.5 18.0 16.8 17.8 13.7 27.9 19.6 16.5 25.1 63.8 13.5 14.8 10.5 23.9 15.3 11.1 22.1 14.9 16.6 18.0 10.4 13.5 14.8 10.0 12.5 4.9 19.8 16.0 11.9 17.3 17.3 13.8 12.1 10.2 17.7 26.9 4.4 16.1 8.5 8.5 18.3 19.1 16.6 18.8 24.6 9.3 21.6 25.2 21.8 13.1 12.5 39.0 24.2 12.7 15.9 15.1 6.9 11.4 9.6 17.0 30.8 12.1 16.1 14.4 16.0 18.7 15.0 17.5 17.8 15.9 19.4 23.0 24.1 27.3 17.8 12.5 8.9 27.3 31.7 19.6 7.1 10.5 16.4 8.0 1.1 2.8 1.1 0.9 0.9 0.6 0.7 0.8 0.8 0.7 0.8 0.7 4.6 1.7 2.0 1.4 0.0 0.4 15.3 21.4 18.2 19.5 14.0 16.8 19.7 18.6 19.1 16.8 19.6 23.9 34.1 9.6 26.3 59.4 18.4 35.7 20.9 10.5 10.2 17.2 23.8 15.6 43.7 17.2 18.2 18.4 16.7 8.2 46.3 36.0 7.9 11.3 17.0 18.7 30.4 23.5 20.4 6.3 71.5 10.7 8.0 22.2 12.8 29.8 20.3 37.4 22.9 13.8 8.8 25.2 89.6 18.5 12.2 33.3 17.5 8.6 12.5 29.0 17.8 80.6 29.0 17.6 21.6 100.5 104.8 14.5 24.6 13.5 28.6 27.3 28.6 15.8 14.3 22.5 19.7 43.4 30.8 54.3 12.3 17.7 39.6 13.0 24.2 17.4 14.9 30.6 SOX1 ENSG00000182968 "SRY-box transcription factor 1" O00570 13 112067149-112071706 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 18 "brain: 14.8" "Group enriched" "Detected in some" 11 "Cardiomyocytes: 4.0;Melanocytes: 3.6;Spermatogonia: 2.4" "Group enriched" "Detected in some" 6 "colorectal cancer: 0.9;glioma: 2.3;melanoma: 2.0" "Region enhanced" "Detected in all" "thalamus: 14.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "AF22: 29.3" "Low region specificity" "Detected in all" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 12: NES - Nervous system development" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (1.12e-1)" "unprognostic (4.95e-2)" "unprognostic (1.71e-3)" "unprognostic (6.03e-2)" "unprognostic (6.41e-2)" "unprognostic (4.85e-1)" "unprognostic (5.93e-2)" 0.0 0.0 2.1 0.0 3.7 0.0 0.0 1.3 2.7 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 5.3 0.0 0.0 0.0 0.0 1.8 4.1 0.0 0.0 0.0 0.1 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.8 14.8 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 29.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 3.7 1.3 2.7 1.6 5.3 1.8 4.1 2.1 1.2 14.8 1.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 2.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 SOX12 SOX22 ENSG00000177732 "SRY-box transcription factor 12" O15370 20 325552-330224 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 52.3;Cone photoreceptor cells: 41.7;Horizontal cells: 32.0;Rod photoreceptor cells: 39.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055052, HPA061627" Enhanced Nucleoplasm No No "Cluster 35: Non-specific - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm "HPA055052: AB_2682685, HPA061627: AB_2684571" "unprognostic (1.02e-1)" "unprognostic (1.33e-2)" "unprognostic (1.18e-3)" "unprognostic (1.30e-3)" "unprognostic (1.81e-3)" "unprognostic (8.80e-2)" "prognostic unfavorable (6.64e-5)" "unprognostic (1.90e-1)" "unprognostic (1.49e-3)" "unprognostic (3.55e-1)" "unprognostic (5.02e-3)" "unprognostic (4.66e-1)" "unprognostic (3.12e-3)" "unprognostic (7.91e-2)" "unprognostic (1.55e-1)" "unprognostic (8.36e-2)" "unprognostic (2.20e-2)" 4.0 8.2 10.1 2.4 9.1 3.0 3.8 12.3 11.4 9.7 6.7 10.6 1.8 9.9 5.1 4.8 8.5 2.1 6.7 9.2 7.5 10.4 4.8 3.9 2.6 10.2 8.1 11.7 6.5 3.7 6.8 2.3 9.2 8.1 1.2 8.5 4.1 6.1 1.1 4.4 5.3 3.7 7.1 6.1 5.4 8.9 8.3 4.0 9.8 1.3 1.7 7.2 6.4 10.6 7.9 27.1 26.0 17.7 12.3 9.0 7.8 10.6 9.2 9.5 9.4 5.5 8.0 17.5 8.0 12.3 19.9 9.2 18.9 3.5 5.4 8.8 13.3 11.3 10.9 55.3 15.8 15.7 2.9 12.4 10.9 8.0 3.2 15.4 12.6 11.8 26.9 9.0 6.2 19.2 5.4 38.4 42.3 4.4 35.3 27.7 6.6 14.2 13.5 1.0 31.7 36.9 7.1 30.9 41.0 10.6 29.4 21.7 14.3 36.5 36.0 1.0 9.5 25.5 28.8 18.1 6.8 15.3 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.2 0.1 0.0 10.1 9.1 12.3 11.4 9.2 7.5 10.2 8.1 9.2 7.1 8.3 10.6 3.8 0.0 3.2 15.3 2.6 3.4 2.5 2.7 15.4 52.3 8.5 6.2 11.3 5.7 0.8 7.3 41.7 1.4 1.6 2.3 15.6 1.3 0.9 12.1 16.2 8.6 9.1 5.5 6.5 0.4 0.4 5.3 0.5 6.6 0.0 22.8 8.9 8.7 2.3 32.0 9.2 4.5 2.0 1.3 4.5 2.0 10.2 1.7 5.4 6.5 0.8 9.9 1.0 10.6 10.1 0.4 0.8 12.4 0.8 3.3 1.1 5.1 1.2 39.1 0.0 3.2 7.6 1.3 6.9 3.9 1.1 0.7 2.9 18.4 3.9 0.5 SP140 "LYSP100-A, LYSP100-B" ENSG00000079263 "SP140 nuclear body protein" Q13342 2 230203110-230313215 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 15.6;lymphoid tissue: 55.8" "Cell type enhanced" "Detected in many" "B-cells: 149.9;dendritic cells: 37.4;NK-cells: 50.4;Plasma cells: 77.2;T-cells: 62.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "memory B-cell: 97.5" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 31.1;HDLM-2: 52.4;Karpas-707: 25.2;RPMI-8226: 16.3" "Low region specificity" "Detected in all" "HPA006162, HPA067493" Enhanced Approved "Nucleoli fibrillar center,Mitochondria" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 57: B-cells - Immune response" "Nucleoli fibrillar center" Mitochondria "HPA006162: AB_1857403, HPA067493: AB_2685851" "unprognostic (8.15e-3)" "unprognostic (2.25e-3)" "unprognostic (3.90e-3)" "unprognostic (5.72e-4)" "unprognostic (5.66e-2)" "unprognostic (3.33e-4)" "unprognostic (1.09e-1)" "unprognostic (1.03e-1)" "unprognostic (6.05e-2)" "unprognostic (1.12e-3)" "unprognostic (3.89e-2)" "unprognostic (2.88e-1)" "unprognostic (1.20e-9)" "unprognostic (9.12e-2)" "unprognostic (8.50e-2)" "unprognostic (3.66e-1)" "unprognostic (9.30e-3)" 1.7 0.8 0.7 25.0 0.8 6.6 1.2 0.8 1.6 0.6 1.0 3.5 2.9 0.9 0.8 0.9 0.7 2.9 0.6 0.8 1.1 0.9 1.6 4.4 54.6 1.8 1.2 0.4 0.3 0.2 0.6 1.2 1.5 0.9 3.9 1.0 2.6 0.5 0.2 1.6 15.6 1.0 1.3 27.8 5.1 1.5 2.1 6.8 1.3 0.1 55.8 4.3 0.7 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.4 2.4 0.0 0.3 31.1 0.0 0.0 5.2 0.0 0.0 0.1 1.8 52.4 0.0 0.0 0.0 0.6 0.2 4.4 0.1 0.5 0.0 0.5 0.6 0.4 0.0 0.3 0.0 25.2 0.6 0.0 0.0 1.5 1.3 0.0 0.0 0.1 2.8 16.3 8.8 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.6 0.1 0.3 1.3 0.0 0.0 9.2 4.0 1.1 2.2 0.7 0.0 0.1 3.5 12.0 23.1 7.3 25.6 97.5 22.8 25.3 8.3 71.0 11.5 15.0 33.4 15.1 10.6 0.5 22.5 10.6 0.7 0.8 0.8 1.6 0.8 1.1 1.8 1.2 1.5 1.3 2.1 1.5 1.6 0.0 2.3 3.9 149.9 0.9 0.0 0.2 0.0 0.7 0.3 0.5 0.5 0.0 0.8 0.0 8.4 0.1 37.4 0.1 0.0 0.0 17.2 0.5 0.2 1.1 0.0 9.7 5.0 0.0 0.2 0.8 1.5 0.1 0.0 0.2 2.2 0.9 11.4 0.0 5.0 0.1 0.0 8.4 8.6 4.8 0.0 13.2 7.2 26.2 13.7 0.5 50.4 2.5 2.8 0.1 0.1 1.2 77.2 0.1 0.0 0.4 2.4 1.7 0.0 0.2 1.0 1.2 0.4 0.7 1.1 0.3 62.1 0.3 0.2 0.2 SPACA3 "ALLP17, CT54, LYC3, LYZL3, SLLP1" ENSG00000141316 "Sperm acrosome associated 3" Q8IXA5 17 32970376-32997877 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 125.3" "Group enriched" "Detected in some" 75 "Early spermatids: 1298.4;Late spermatids: 933.6" "Cancer enhanced" "Detected in some" "colorectal cancer: 0.9" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 5 "memory B-cell: 1.2" "Lineage enriched" "Detected in single" 5 "B-cells: 1.2" "Cell line enriched" "Detected in some" 16 "U-266/70: 91.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA023633 Enhanced "Secreted in male reproductive system" NA NA "Cluster 37: B-cells - Transcription" "Cluster 83: Testis - Spermatogenesis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 29: Early spermatids - Spermatogenesis" "HPA023633: AB_1857407" "unprognostic (6.48e-2)" "unprognostic (2.83e-1)" "unprognostic (1.30e-1)" "unprognostic (7.08e-2)" "unprognostic (1.16e-2)" "unprognostic (1.31e-2)" "unprognostic (3.37e-1)" "unprognostic (5.91e-2)" "unprognostic (1.68e-1)" "unprognostic (5.70e-4)" "unprognostic (3.86e-2)" "unprognostic (1.79e-1)" "unprognostic (4.63e-1)" 0.1 0.0 0.2 0.1 0.0 0.3 0.1 0.7 0.3 0.0 0.1 0.1 0.0 0.1 0.2 0.2 0.2 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.1 20.9 0.0 0.0 0.1 0.1 0.1 0.1 0.2 0.2 0.0 0.0 0.3 0.3 0.1 0.0 0.0 0.2 125.3 0.1 0.0 0.2 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 5.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.3 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 91.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.7 0.3 0.2 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1298.4 0.0 0.0 0.6 0.0 0.0 0.0 1.1 0.0 1.6 0.0 0.0 3.8 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 933.6 13.1 1.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.2 4.9 0.4 0.0 3.8 0.0 0.7 0.0 6.6 0.0 0.0 14.7 6.9 0.0 0.0 0.0 0.0 0.1 0.9 0.0 SPACA9 "C9orf9, Mast" ENSG00000165698 "Sperm acrosome associated 9" Q96E40 9 132878027-132890201 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 74.0;testis: 131.2" "Cell type enhanced" "Detected in many" "Collecting duct cells: 23.9;Distal tubular cells: 33.2;Endometrial ciliated cells: 99.8;Proximal tubular cells: 23.9;Respiratory ciliated cells: 63.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in many" 4 "JURKAT: 48.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA022243, HPA051600" Enhanced Approved Mitochondria No No "Cluster 19: B-cells - Humoral immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 49: Ciliated cells - Cilium organization" Mitochondria "HPA022243: AB_1845844, HPA051600: AB_2681546" "unprognostic (2.69e-1)" "unprognostic (2.14e-3)" "unprognostic (8.00e-3)" "prognostic favorable (8.61e-4)" "unprognostic (1.59e-1)" "unprognostic (5.73e-2)" "unprognostic (3.76e-3)" "unprognostic (2.60e-1)" "unprognostic (6.43e-2)" "unprognostic (1.12e-1)" "unprognostic (1.15e-2)" "unprognostic (9.51e-2)" "prognostic favorable (8.31e-4)" "unprognostic (5.11e-2)" "unprognostic (1.22e-2)" "unprognostic (1.20e-1)" "unprognostic (1.22e-2)" 5.0 7.6 17.4 1.3 17.7 1.5 5.2 17.4 19.5 9.7 18.2 11.5 1.3 8.3 74.0 9.5 39.2 5.4 10.4 16.8 19.0 12.2 2.3 7.4 2.2 20.3 22.2 11.3 5.2 3.8 11.5 3.2 19.1 7.0 1.9 8.2 9.8 7.1 1.7 11.9 3.7 4.9 21.3 3.6 6.5 131.2 18.5 7.9 15.6 1.8 3.2 6.1 8.1 19.0 3.0 3.2 4.8 3.9 6.6 8.4 5.7 1.9 3.5 2.6 2.8 0.8 9.1 0.7 4.3 8.7 5.4 4.2 2.0 5.4 2.3 3.5 3.9 0.8 2.3 1.0 9.6 2.2 0.3 9.6 11.4 6.4 6.9 10.6 3.0 48.5 0.8 2.4 7.1 6.4 7.6 8.6 1.0 5.6 3.0 3.6 1.0 2.1 10.5 1.1 1.2 4.7 8.0 1.3 6.3 3.6 10.3 0.7 2.9 5.5 3.7 5.3 0.8 1.0 1.7 2.6 10.2 0.8 2.7 4.0 1.1 1.9 1.1 1.1 1.3 3.0 1.2 0.6 1.6 2.6 1.3 1.3 1.5 4.4 1.9 0.5 2.0 0.9 17.4 17.7 17.4 19.5 16.8 19.0 20.3 22.2 19.1 21.3 18.5 19.0 3.6 3.2 2.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 10.3 17.9 0.0 0.0 5.0 23.9 0.0 18.2 0.8 0.0 33.2 8.6 0.0 99.8 7.1 1.9 0.0 0.0 0.0 7.1 12.4 3.9 0.0 8.1 0.0 6.7 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 23.9 63.4 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 7.3 0.8 7.7 0.0 0.0 SPAG4 "CT127, SUN4" ENSG00000061656 "Sperm associated antigen 4" Q9NPE6 20 35615829-35621094 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "pancreas: 90.1;testis: 32.0" "Group enriched" "Detected in many" 4 "Early spermatids: 177.9;Late spermatids: 139.8;Plasma cells: 138.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "EFO-21: 26.0;hTERT-RPE1: 18.4;U-87 MG: 47.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA048393, HPA061789" Approved NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 25: Pancreas - Digestion" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 55: Plasma cells - Humoral immune response" "HPA048393: AB_2680385, HPA061789: AB_2684609" "unprognostic (1.05e-1)" "unprognostic (5.61e-2)" "prognostic unfavorable (1.09e-5)" "prognostic favorable (9.52e-8)" "prognostic unfavorable (6.31e-5)" "unprognostic (1.05e-1)" "unprognostic (2.56e-3)" "unprognostic (1.21e-2)" "unprognostic (2.29e-1)" "unprognostic (4.77e-2)" "unprognostic (4.49e-3)" "unprognostic (1.98e-1)" "prognostic unfavorable (1.28e-4)" "unprognostic (3.59e-2)" "unprognostic (1.66e-1)" "unprognostic (1.79e-1)" "prognostic favorable (6.66e-4)" 3.1 5.3 2.3 3.1 2.9 5.0 2.3 2.0 4.4 3.7 2.8 7.0 6.5 2.2 5.5 2.1 4.6 4.2 3.2 2.0 2.7 5.1 4.8 3.1 3.2 3.7 3.7 8.5 90.1 3.1 8.2 1.4 3.6 3.7 2.6 5.4 7.2 2.2 0.6 0.6 5.9 1.4 2.0 12.3 7.3 32.0 2.2 0.9 2.2 0.1 5.5 6.9 2.5 2.2 3.8 1.6 0.8 2.0 2.0 0.7 10.5 1.4 1.9 1.5 2.2 3.4 8.3 0.3 26.0 2.1 6.0 1.0 0.5 5.2 1.6 4.1 0.5 2.9 3.2 3.7 10.2 2.2 4.7 4.9 1.1 1.6 1.2 18.4 3.1 0.9 0.8 7.0 3.9 8.0 0.8 5.4 0.1 7.2 6.9 0.6 0.7 11.4 2.7 1.6 0.6 3.9 1.8 1.2 3.0 0.3 5.2 0.9 3.3 7.2 1.1 1.6 1.5 13.8 5.7 3.2 47.4 0.8 1.3 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.4 0.0 2.3 2.9 2.0 4.4 2.0 2.7 3.7 3.7 3.6 2.0 2.2 2.2 3.2 0.0 0.5 0.3 26.6 0.4 1.0 6.3 1.2 3.2 1.7 1.5 2.3 0.0 7.6 0.0 2.1 2.0 7.6 0.6 0.0 13.2 177.9 7.5 2.3 3.4 4.2 0.4 1.9 7.6 15.9 3.3 5.1 6.0 4.5 0.9 5.7 6.7 1.5 1.7 1.2 1.7 24.4 1.4 2.1 139.8 1.8 2.0 26.6 1.9 2.1 14.7 0.0 0.0 0.3 15.5 1.4 3.0 138.0 1.6 0.3 6.0 19.3 2.5 0.0 1.0 3.6 35.0 4.9 0.4 0.1 20.2 7.2 2.3 0.8 3.9 SPAG5 "DEEPEST, hMAP126, MAP126" ENSG00000076382 "Sperm associated antigen 5" Q96R06 17 28577565-28599025 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 37.9;kidney: 37.8;testis: 74.0" "Cell type enhanced" "Detected in many" "Early spermatids: 126.0;Erythroid cells: 37.2;Spermatocytes: 72.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 11.7;T-reg: 4.9" "Group enriched" "Detected in many" 6 "granulocytes: 11.7;T-cells: 4.9" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA022008, HPA022479, HPA024418" Approved Supported "Nuclear bodies,Mitotic spindle,Cytosol" Yes Yes "Cluster 34: Basophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear bodies, Mitotic spindle" Cytosol "HPA022008: AB_1853519, HPA022479: AB_1853521, HPA024418: " "unprognostic (4.71e-2)" "unprognostic (1.32e-1)" "unprognostic (5.31e-3)" "unprognostic (2.32e-3)" "unprognostic (3.50e-1)" "unprognostic (1.55e-1)" "prognostic unfavorable (5.43e-5)" "unprognostic (3.37e-3)" "unprognostic (4.84e-3)" "unprognostic (5.97e-2)" "prognostic unfavorable (3.02e-4)" "unprognostic (3.49e-2)" "prognostic unfavorable (5.43e-13)" "unprognostic (2.64e-1)" "unprognostic (1.66e-1)" "unprognostic (2.90e-2)" "unprognostic (2.01e-1)" 2.2 3.3 7.8 7.8 7.6 37.9 2.4 5.8 9.1 2.6 3.4 8.3 7.9 1.9 2.4 8.3 1.7 1.8 1.4 7.6 7.7 37.8 14.8 3.4 14.5 6.7 6.8 2.7 1.5 1.1 4.3 5.7 6.7 2.2 10.7 10.8 2.4 0.8 1.0 5.5 9.1 3.4 5.0 7.4 3.6 74.0 7.7 22.4 8.7 0.7 17.3 2.6 3.6 7.5 84.7 87.7 103.3 78.4 5.2 8.6 42.4 65.9 42.4 98.1 78.3 69.2 25.5 59.8 34.2 46.8 91.7 70.2 114.5 42.7 103.8 108.6 72.9 62.9 87.9 80.2 0.6 83.1 76.1 2.9 3.8 78.6 40.4 14.5 52.1 90.6 69.7 101.5 80.7 52.6 109.4 92.9 54.2 68.3 44.5 72.1 144.4 70.9 29.0 43.0 78.6 45.8 96.4 114.9 31.6 84.9 82.2 70.6 25.7 56.4 91.3 46.6 114.6 46.7 72.9 87.3 37.8 60.6 91.8 11.7 0.0 0.0 0.4 0.4 0.7 0.6 1.2 0.9 0.1 1.4 1.1 0.9 0.2 0.8 0.3 0.3 4.9 0.9 7.8 7.6 5.8 9.1 7.6 7.7 6.7 6.8 6.7 5.0 7.7 7.5 0.5 3.2 1.7 0.7 3.3 2.0 0.9 1.3 1.2 5.0 1.1 1.0 0.7 0.0 1.9 0.0 0.0 9.0 1.3 4.7 1.9 0.5 126.0 6.0 1.1 1.5 13.1 37.2 5.2 0.4 12.2 2.6 5.1 1.8 1.3 12.6 3.3 6.3 6.5 3.3 6.0 4.6 4.1 2.7 4.0 25.2 0.9 6.1 0.0 1.9 0.9 0.7 0.0 2.0 1.7 0.4 4.7 0.0 13.1 0.8 8.1 12.5 7.7 3.9 6.6 2.0 2.2 72.6 21.0 5.2 1.0 3.8 2.8 0.9 5.1 1.1 SPARCL1 MAST9 ENSG00000152583 "SPARC like 1" Q14515 4 87473335-87531061 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 4430.9;Endothelial cells: 2372.1;Peritubular cells: 2523.5;Sertoli cells: 4674.1;Skeletal myocytes: 2379.0;Smooth muscle cells: 2781.9" "Cancer enhanced" "Detected in all" "glioma: 528.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "AF22: 24.9;SuSa: 31.4;U-266/70: 9.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB026225 Enhanced "Secreted in other tissues" NA NA 630000000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB026225: " "unprognostic (1.02e-2)" "unprognostic (2.81e-2)" "prognostic unfavorable (4.06e-4)" "unprognostic (1.19e-1)" "unprognostic (1.79e-2)" "unprognostic (4.93e-2)" "unprognostic (1.63e-3)" "unprognostic (1.73e-2)" "unprognostic (3.88e-2)" "unprognostic (6.04e-2)" "unprognostic (1.28e-1)" "unprognostic (1.17e-1)" "unprognostic (2.45e-3)" "unprognostic (1.76e-2)" "unprognostic (5.72e-2)" "unprognostic (2.88e-3)" "prognostic unfavorable (3.33e-4)" 755.6 129.5 664.6 124.5 810.9 0.5 532.1 612.4 1058.4 732.7 580.4 624.3 125.1 1244.5 443.8 308.1 754.5 487.9 600.2 744.6 723.5 72.5 25.0 481.1 99.1 655.7 730.9 286.8 91.8 128.0 197.8 315.4 663.4 584.2 187.5 95.2 228.3 999.2 244.8 130.2 280.1 1191.2 774.7 157.9 347.7 97.5 694.8 103.2 369.9 594.7 100.0 488.0 466.4 681.2 0.7 0.0 24.9 0.3 0.2 0.1 2.6 0.1 0.1 0.0 0.0 0.0 0.1 0.4 1.8 0.0 0.0 1.4 2.4 0.0 0.0 1.7 0.0 0.3 1.1 0.4 1.1 0.3 1.2 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 3.3 0.0 0.5 0.2 3.5 0.6 0.0 0.0 0.3 0.4 1.2 0.0 0.1 0.8 1.6 0.1 0.2 0.1 31.4 0.4 0.5 0.0 0.2 0.3 1.5 0.2 9.1 1.4 0.6 3.4 0.5 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 664.6 810.9 612.4 1058.4 744.6 723.5 655.7 730.9 663.4 774.7 694.8 681.2 4430.9 12.8 56.4 1155.7 6.2 46.3 187.2 0.6 59.7 10.7 24.4 251.6 334.2 4.3 43.3 7.3 2.1 2.2 8.6 0.0 13.7 0.8 11.8 34.9 935.8 2372.1 0.0 32.0 382.3 0.4 3.2 1413.1 6.1 46.7 7.6 1.4 899.5 9.1 9.2 3.3 450.1 0.0 0.0 5.3 55.2 47.0 659.5 31.6 56.9 261.4 0.0 179.4 0.0 210.6 53.8 0.1 0.0 2523.5 25.2 50.4 0.0 24.6 7.4 34.4 4674.1 2379.0 2781.9 5.7 7.9 56.8 39.9 2.5 26.9 38.8 0.0 124.2 SPATA12 ENSG00000186451 "Spermatogenesis associated 12" Q7Z6I5 3 57060664-57075432 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "testis: 20.5" "Group enriched" "Detected in some" 145 "Early spermatids: 464.2;Late spermatids: 1195.5" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 1.9;RH-30: 1.1" "HPA043323, HPA075578" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" No No "Cluster 78: Testis - Spermatogenesis" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA043323: AB_10796792, HPA075578: " "unprognostic (2.31e-1)" "unprognostic (2.18e-4)" "unprognostic (3.47e-4)" "unprognostic (2.21e-2)" "unprognostic (2.66e-1)" "unprognostic (8.79e-3)" "unprognostic (1.69e-3)" "unprognostic (3.82e-2)" "unprognostic (1.35e-1)" "unprognostic (1.29e-1)" "unprognostic (6.80e-2)" "unprognostic (1.76e-2)" "unprognostic (4.71e-3)" "unprognostic (7.29e-2)" "unprognostic (1.62e-2)" "unprognostic (1.14e-1)" "unprognostic (2.44e-3)" 0.0 0.3 0.4 0.0 0.3 0.0 0.0 0.2 0.2 0.1 2.1 0.1 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.2 0.6 0.0 0.0 0.3 0.2 2.0 0.8 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.3 20.5 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.1 0.1 0.0 1.9 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.4 0.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.4 0.5 0.0 1.1 0.0 0.7 0.4 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.3 0.0 0.7 0.1 0.1 0.0 0.1 0.3 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.2 0.2 0.2 0.6 2.0 0.8 0.7 0.5 0.4 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.3 0.3 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 1.4 464.2 1.0 0.1 0.6 0.0 0.0 0.1 1.0 0.0 0.2 0.0 0.7 0.0 0.0 0.0 0.0 3.1 0.0 0.1 0.0 0.0 1.3 0.0 1195.5 5.0 0.5 0.0 1.0 0.0 0.0 0.0 1.0 0.7 1.4 0.1 5.7 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 4.8 2.8 0.3 0.0 0.0 0.3 0.0 0.2 0.5 SPATA18 FLJ32906 ENSG00000163071 "Spermatogenesis associated 18" Q8TC71 4 52051304-52097299 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 68.3;testis: 28.8" "Cell type enriched" "Detected in many" 4 "Late spermatids: 2341.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 31.5;BEWO: 24.4;BJ hTERT+: 15.9;HSkMC: 29.3;hTCEpi: 28.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA036854, HPA036855" Enhanced Supported Mitochondria NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 28: BEWO - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria "HPA036854: AB_10670927, HPA036855: AB_2675352" "unprognostic (6.54e-2)" "unprognostic (1.90e-1)" "unprognostic (1.46e-1)" "prognostic favorable (1.32e-5)" "unprognostic (1.02e-2)" "unprognostic (1.53e-2)" "unprognostic (7.27e-2)" "unprognostic (4.49e-2)" "unprognostic (1.76e-1)" "unprognostic (2.73e-1)" "unprognostic (3.13e-1)" "unprognostic (3.13e-2)" "prognostic favorable (3.73e-9)" "unprognostic (4.38e-1)" "unprognostic (1.39e-1)" "unprognostic (1.01e-2)" "unprognostic (4.00e-2)" 2.1 5.0 2.4 0.7 2.2 0.0 6.3 1.3 1.0 10.7 15.6 4.1 2.1 4.2 2.0 4.6 68.3 6.7 1.8 2.5 2.7 5.3 5.4 8.0 0.3 6.8 8.3 1.8 2.0 4.5 4.9 1.9 5.5 4.2 5.6 0.1 10.1 5.6 0.8 6.6 2.2 3.1 6.0 0.6 4.9 28.8 2.6 3.2 1.2 1.3 0.9 2.8 3.4 3.8 0.0 3.8 1.8 0.0 12.7 31.5 24.4 9.3 15.9 0.6 0.7 0.0 1.5 0.0 0.0 12.3 0.2 0.3 0.1 7.1 0.3 0.0 1.1 0.0 0.0 8.0 11.2 0.0 0.0 29.3 28.7 1.0 4.5 5.1 6.9 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.4 1.9 2.0 1.0 0.0 0.0 9.7 0.0 0.2 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 2.2 1.3 1.0 2.5 2.7 6.8 8.3 5.5 6.0 2.6 3.8 0.3 9.6 3.0 0.3 0.0 5.2 8.5 9.4 8.6 0.0 6.0 6.7 2.2 8.6 15.1 0.0 0.0 1.7 0.3 1.8 1.9 1.2 561.1 124.6 1.8 1.2 1.8 0.0 1.7 2.6 1.8 4.3 11.2 4.7 2.5 1.9 1.4 3.4 0.3 0.0 0.5 1.6 6.1 0.6 1.6 2341.5 10.8 1.1 0.0 2.8 0.1 0.0 0.0 0.5 0.1 2.0 2.7 10.9 0.0 5.1 1.9 7.4 141.4 0.0 0.0 1.8 3.9 13.9 7.1 7.1 7.5 0.8 0.2 2.5 4.3 6.8 SPATA19 "CT132, FLJ25851, SPAS1, spergen1" ENSG00000166118 "Spermatogenesis associated 19" Q7Z5L4 11 133840631-133845538 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 321 "testis: 134.6" "Group enriched" "Detected in some" 162 "Early spermatids: 771.9;Late spermatids: 2291.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA040082 Enhanced NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 34: Spermatids - Unknown function" "HPA040082: AB_2676836" "unprognostic (9.90e-3)" "unprognostic (3.34e-2)" "unprognostic (2.66e-1)" 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 134.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 771.9 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2291.2 9.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SPATA20 "FLJ21347, SSP411, Tisp78" ENSG00000006282 "Spermatogenesis associated 20" Q8TB22 17 50543058-50555852 "Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 117.5" "Group enriched" "Detected in all" 15 "Early spermatids: 594.1;Late spermatids: 1543.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 60.1;MCF7: 59.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA022023, HPA027144, HPA031442" Enhanced Approved Nucleoplasm "Secreted in male reproductive system" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 43: Testis - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "HPA022023: AB_1857417, HPA027144: AB_1857418, HPA031442: AB_10610557" "unprognostic (9.27e-3)" "unprognostic (1.90e-1)" "unprognostic (9.60e-2)" "unprognostic (9.74e-3)" "unprognostic (2.63e-3)" "unprognostic (7.23e-2)" "unprognostic (1.56e-1)" "unprognostic (3.07e-1)" "unprognostic (7.09e-2)" "unprognostic (8.71e-2)" "unprognostic (6.12e-3)" "unprognostic (4.93e-2)" "unprognostic (6.74e-2)" "unprognostic (1.75e-1)" "unprognostic (2.29e-1)" "unprognostic (2.66e-1)" "prognostic favorable (9.69e-5)" 10.3 36.8 25.7 7.2 24.6 4.4 10.5 25.5 33.2 16.9 30.0 14.8 10.0 18.0 9.7 10.1 13.7 12.9 33.3 24.2 27.6 18.6 17.6 8.9 6.4 26.9 28.0 21.1 22.0 17.0 11.7 6.4 27.5 17.1 6.4 3.2 17.7 11.2 18.5 8.6 10.8 8.3 26.0 14.1 22.0 117.5 33.1 2.3 22.5 18.4 3.8 14.6 10.3 24.8 8.8 39.4 4.8 25.7 7.9 22.7 6.0 14.9 24.2 9.2 7.3 29.1 12.9 9.2 38.4 13.9 8.9 7.0 1.4 6.3 4.2 14.4 5.3 7.4 9.5 60.1 27.8 2.4 17.1 33.3 8.8 4.7 13.0 17.9 11.6 2.4 0.7 16.8 5.5 59.3 0.0 2.1 3.1 19.0 18.0 4.4 6.9 2.9 35.4 39.5 4.5 11.3 13.0 12.1 17.0 5.6 21.0 1.1 19.7 9.8 22.2 5.6 3.7 31.8 14.0 0.2 14.9 1.4 6.9 0.0 5.0 1.0 1.6 4.5 1.9 2.8 1.2 1.1 8.3 1.7 1.5 1.7 0.2 7.3 3.4 1.6 0.8 3.7 25.7 24.6 25.5 33.2 24.2 27.6 26.9 28.0 27.5 26.0 33.1 24.8 12.6 6.4 5.0 17.3 14.0 10.7 15.1 13.4 25.6 5.3 13.3 17.4 32.5 20.0 13.1 23.9 4.2 17.3 9.8 32.6 27.4 35.6 594.1 13.0 13.2 11.7 37.9 6.1 10.3 39.0 10.3 23.5 66.8 23.2 17.7 38.5 10.8 26.7 34.6 11.8 9.5 28.4 16.2 23.6 14.8 1543.1 38.2 20.0 21.4 6.5 19.3 26.9 12.3 8.5 2.3 23.7 31.1 38.0 17.9 12.2 18.4 38.8 5.9 2.4 6.6 18.1 19.1 10.0 13.8 11.9 8.8 9.9 11.2 39.9 23.8 17.1 SPATA24 "CCDC161, T6441" ENSG00000170469 "Spermatogenesis associated 24" Q86W54 5 139396563-139404089 "Predicted intracellular proteins" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "testis: 147.0" "Group enriched" "Detected in many" 26 "Early spermatids: 1073.6;Late spermatids: 2829.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 85.6" HPA044000 Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 44: HDLM-2 - Immune response" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Cytosol" "HPA044000: AB_10959668" "unprognostic (2.19e-3)" "unprognostic (1.18e-1)" "unprognostic (2.09e-1)" "unprognostic (9.30e-2)" "unprognostic (3.82e-1)" "unprognostic (7.71e-2)" "prognostic unfavorable (2.75e-4)" "unprognostic (1.26e-2)" "unprognostic (1.58e-1)" "unprognostic (2.87e-2)" "unprognostic (5.36e-3)" "unprognostic (1.07e-1)" "unprognostic (6.11e-2)" "unprognostic (1.24e-1)" "unprognostic (3.44e-1)" "unprognostic (1.46e-1)" "unprognostic (1.64e-1)" 2.9 7.1 6.1 2.9 5.4 1.8 4.1 5.5 7.1 3.3 5.8 4.6 6.5 4.1 21.0 3.4 15.0 3.8 20.6 5.9 6.6 15.0 5.1 3.1 7.2 7.8 8.0 4.2 5.3 12.5 12.7 3.1 7.0 4.9 2.9 6.5 6.6 4.0 23.0 2.9 7.1 2.9 7.6 4.0 4.3 147.0 6.2 3.1 7.3 19.2 5.4 3.9 3.2 6.1 13.4 8.4 11.6 6.3 3.3 6.5 9.2 3.3 6.3 7.0 12.0 18.7 17.2 21.0 9.5 6.4 23.5 7.3 8.7 14.6 7.4 85.6 10.4 6.5 15.7 14.4 12.7 1.4 11.1 5.7 7.1 10.2 12.6 7.7 8.3 13.3 6.5 36.1 9.3 7.4 13.8 10.1 8.5 5.4 7.1 31.6 7.5 28.9 16.3 7.2 8.8 8.0 12.8 24.2 6.0 28.0 7.0 14.5 15.3 4.1 5.3 7.7 9.5 8.7 8.9 19.4 7.6 10.8 3.4 0.0 2.1 1.5 3.0 1.6 4.1 3.5 3.1 3.5 2.4 1.9 3.4 4.8 0.1 2.0 0.6 1.4 1.5 1.5 6.1 5.4 5.5 7.1 5.9 6.6 7.8 8.0 7.0 7.6 6.2 6.1 2.2 0.0 4.1 2.6 3.4 1.7 6.4 6.4 2.8 0.3 3.8 3.4 24.7 7.2 3.7 5.5 8.4 6.0 2.3 3.0 13.7 4.6 1073.6 14.9 1.6 4.1 0.0 0.8 1.0 1.8 3.2 2.2 2.0 2.4 0.0 3.6 4.2 3.7 5.2 1.7 1.3 1.5 2.0 2.7 1.4 2829.6 14.3 2.4 1.8 0.0 1.5 3.3 7.2 0.5 0.9 2.6 3.1 13.5 1.7 3.3 6.8 36.5 20.8 1.4 26.3 3.7 4.1 75.0 18.2 2.4 1.8 4.5 3.2 8.5 3.1 5.4 SPATA31E1 "C9orf79, FAM75E1, FLJ35866" ENSG00000177992 "SPATA31 subfamily E member 1" Q6ZUB1 9 87882877-87888903 "Predicted membrane proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 76 "brain: 7.5;testis: 7.6" "Group enriched" "Detected in some" 95 "Early spermatids: 43.3;Late spermatids: 14.2" "Not detected" "Not detected" "Region enriched" "Detected in single" 13 "hippocampal formation: 7.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 1.7;SCLC-21H: 1.4" "Low region specificity" "Detected in some" HPA024253 Enhanced NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 29: Early spermatids - Spermatogenesis" "HPA024253: AB_1845839" "unprognostic (2.16e-1)" "unprognostic (2.29e-2)" "unprognostic (4.72e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 SPATA32 "AEP2, C17orf46, FLJ25414, TEX34, VAD1.2" ENSG00000184361 "Spermatogenesis associated 32" Q96LK8 17 45254393-45262094 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 76 "testis: 43.6" "Group enriched" "Detected in some" 98 "Early spermatids: 194.2;Late spermatids: 615.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA024549 Approved NA NA "Cluster 30: Non-specific - Translation" "Cluster 83: Testis - Spermatogenesis" "Cluster 31: Spermatids - Spermatogenesis" "HPA024549: AB_1845589" "unprognostic (5.27e-2)" "unprognostic (1.15e-1)" "unprognostic (5.88e-2)" "unprognostic (1.79e-4)" "unprognostic (7.84e-2)" "unprognostic (1.36e-2)" "unprognostic (3.58e-1)" "unprognostic (6.76e-2)" "unprognostic (1.39e-1)" "unprognostic (1.28e-1)" "unprognostic (1.37e-1)" "unprognostic (3.76e-1)" "unprognostic (2.87e-3)" "unprognostic (8.93e-4)" "unprognostic (1.49e-1)" "unprognostic (1.41e-2)" "unprognostic (5.75e-4)" 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 43.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.9 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.4 0.5 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.7 0.8 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.3 0.3 0.0 0.3 0.6 0.3 0.1 0.1 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.2 1.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 194.2 0.1 0.1 0.2 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 615.3 2.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 1.1 0.0 2.7 2.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 SPATA5 "AFG2, SPAF" ENSG00000145375 "Spermatogenesis associated 5" Q8NB90 4 122923070-123319433 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Chaperone, Developmental protein, Hydrolase" "Deafness, Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 207.9;Inhibitory neurons: 59.0;Microglial cells: 104.0;Oligodendrocyte precursor cells: 79.9;Oligodendrocytes: 91.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036450, HPA036451" Approved Approved Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" Cytosol "HPA036450: AB_2675131, HPA036451: AB_10670107" "unprognostic (4.28e-1)" "unprognostic (7.54e-2)" "unprognostic (7.37e-3)" "unprognostic (1.26e-1)" "unprognostic (5.16e-1)" "unprognostic (1.18e-1)" "unprognostic (7.65e-4)" "unprognostic (1.95e-3)" "unprognostic (9.00e-2)" "unprognostic (2.78e-1)" "unprognostic (4.43e-3)" "unprognostic (4.62e-2)" "unprognostic (1.26e-2)" "unprognostic (1.52e-1)" "unprognostic (5.68e-1)" "unprognostic (2.63e-2)" "unprognostic (1.79e-1)" 1.3 0.8 0.8 0.9 1.1 1.4 1.6 2.3 1.0 1.3 1.2 1.0 0.6 1.3 0.8 1.0 1.0 0.8 0.9 0.6 1.2 1.1 1.1 0.9 1.2 1.2 1.1 1.2 0.8 1.5 0.7 1.4 1.2 1.1 1.2 2.2 1.0 1.1 1.3 1.2 0.7 1.3 1.0 1.3 2.3 3.6 1.0 2.0 1.5 1.2 1.2 1.0 1.1 1.3 2.3 3.2 2.9 7.1 2.4 1.7 1.9 4.0 1.6 3.3 3.3 1.5 3.2 3.7 2.4 2.4 2.4 2.0 5.0 2.2 5.6 6.2 0.9 3.8 5.7 2.5 1.1 5.2 4.0 1.2 1.1 3.8 3.3 1.7 3.4 2.4 7.7 6.2 4.6 2.4 10.1 3.2 2.1 3.6 1.3 3.3 7.2 2.4 1.9 1.9 4.8 3.1 3.2 2.3 1.7 4.2 2.2 2.0 2.6 6.9 5.2 4.6 4.2 3.9 5.0 3.3 3.3 4.4 6.2 0.5 0.2 0.2 0.6 0.6 0.4 0.5 0.5 0.5 0.1 0.5 0.5 0.5 0.3 0.5 0.2 0.7 0.3 0.2 0.8 1.1 2.3 1.0 0.6 1.2 1.2 1.1 1.2 1.0 1.0 1.3 10.7 16.0 5.0 34.6 9.1 5.1 5.6 2.6 6.2 6.2 4.2 3.2 4.3 11.5 7.4 1.8 14.6 5.1 6.7 2.9 0.0 3.1 207.9 4.5 9.6 8.5 2.4 11.2 48.8 3.6 4.3 5.1 14.3 5.2 5.1 8.6 4.2 3.2 3.5 3.3 59.0 2.6 0.0 4.1 5.3 25.0 7.2 5.3 0.0 104.0 1.8 4.0 4.1 79.9 91.4 4.2 2.1 4.5 10.6 3.9 1.5 3.1 6.4 11.3 0.0 12.5 6.6 14.7 10.6 5.0 5.4 2.2 9.9 4.7 4.1 3.0 SPCS1 "HSPC033, SPC1, SPC12, YJR010C-A" ENSG00000114902 "Signal peptidase complex subunit 1" Q9Y6A9 3 52704955-52711148 "Metabolic proteins, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 1177.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046091, HPA055273" Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 16: U-266 - Nucleosome" "Cluster 25: Spermatids - Spermatogenesis" "Golgi apparatus, Vesicles" "HPA046091: AB_10959614, HPA055273: AB_2682768" "unprognostic (5.47e-2)" "unprognostic (4.04e-1)" "prognostic favorable (9.28e-4)" "unprognostic (5.93e-2)" "unprognostic (6.88e-2)" "unprognostic (1.10e-2)" "unprognostic (3.22e-1)" "unprognostic (1.60e-1)" "unprognostic (1.91e-1)" "unprognostic (5.56e-2)" "unprognostic (3.89e-1)" "unprognostic (1.15e-1)" "prognostic favorable (2.90e-4)" "unprognostic (5.96e-2)" "unprognostic (1.80e-1)" "unprognostic (3.58e-1)" "unprognostic (3.09e-2)" 95.3 154.7 75.1 64.1 76.6 61.3 100.5 80.7 101.1 97.4 88.7 110.1 94.8 101.0 110.8 117.0 92.1 48.4 119.7 75.4 83.9 137.3 172.8 87.8 71.2 82.3 80.5 91.1 231.2 89.5 141.1 59.4 82.1 96.3 84.7 124.6 145.2 79.1 142.2 109.0 103.9 53.0 81.7 105.6 151.1 153.2 81.4 66.6 113.2 49.7 87.1 103.0 94.7 84.9 114.6 102.2 113.4 139.3 164.9 134.4 157.2 157.6 144.5 139.4 128.4 108.1 171.0 114.6 65.7 145.4 142.5 110.2 109.9 142.5 149.1 154.3 115.8 138.6 169.2 164.6 175.1 213.3 229.1 104.7 190.5 148.5 174.4 130.5 117.4 147.5 118.8 418.0 151.8 105.5 168.8 207.2 195.8 317.2 203.9 67.9 95.7 608.6 232.7 148.3 73.6 157.4 148.7 178.1 224.2 102.4 188.1 248.1 106.2 127.3 119.1 226.3 192.1 406.2 654.1 169.8 196.5 209.4 169.8 292.7 129.9 258.2 131.1 137.0 155.1 202.0 158.5 144.2 143.9 149.3 146.8 152.1 100.1 119.6 152.5 620.5 177.1 253.8 75.1 76.6 80.7 101.1 75.4 83.9 82.3 80.5 82.1 81.7 81.4 84.9 172.5 64.1 104.2 23.8 282.3 156.5 227.9 470.7 136.1 465.4 289.0 351.0 148.7 221.6 283.6 310.8 118.9 373.5 488.1 195.2 361.9 353.8 597.8 286.4 180.8 157.6 167.7 143.9 27.1 339.4 399.8 181.9 119.8 181.5 211.6 138.7 131.4 301.8 311.0 102.6 34.4 291.3 325.5 202.9 189.9 1177.6 216.3 192.5 380.6 13.1 321.9 296.9 213.1 21.1 53.2 274.8 274.1 191.8 888.8 295.0 405.5 665.1 374.1 251.3 164.3 152.6 335.5 746.4 504.5 195.8 184.4 351.2 220.8 283.6 267.7 285.3 SPDYE1 "Ringo1, SPDYE, WBSCR19" ENSG00000136206 "Speedy/RINGO cell cycle regulator family member E1" Q8NFV5 7 43997897-44010122 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "testis: 7.2" "Group enriched" "Detected in some" 9 "Early spermatids: 54.5;Late spermatids: 56.5" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" HPA051750 Supported NA NA "Cluster 46: Basophils - DNA binding" "Cluster 78: Testis - Spermatogenesis" "Cluster 20: HeLa - Mitochondria" "Cluster 29: Early spermatids - Spermatogenesis" "HPA051750: AB_2681590" "unprognostic (2.16e-1)" "unprognostic (1.44e-1)" "unprognostic (3.98e-2)" "unprognostic (6.20e-2)" "unprognostic (1.22e-1)" "unprognostic (1.19e-1)" "unprognostic (1.54e-2)" "unprognostic (1.27e-1)" "unprognostic (8.93e-2)" "unprognostic (1.19e-1)" "unprognostic (2.22e-1)" "unprognostic (4.69e-2)" "unprognostic (1.95e-6)" "unprognostic (2.68e-1)" "unprognostic (2.32e-1)" "unprognostic (1.55e-1)" "unprognostic (5.19e-2)" 0.2 0.2 0.6 0.8 1.3 2.0 0.1 1.4 1.1 0.3 0.3 0.2 0.7 0.2 0.0 0.2 0.1 0.3 0.2 0.7 0.1 0.2 0.2 0.2 0.8 0.7 0.3 0.3 0.3 0.0 0.2 0.2 0.2 0.2 0.0 1.0 0.6 0.0 2.5 1.7 0.6 0.0 0.0 0.8 0.5 7.2 1.1 0.0 0.5 0.0 0.0 0.2 0.2 1.7 1.1 0.9 1.1 1.1 0.0 0.0 1.3 0.6 0.0 0.0 0.0 0.8 0.6 1.1 0.6 0.0 0.4 1.7 0.0 0.0 0.0 0.8 0.9 0.5 2.8 0.5 0.0 1.9 1.0 0.0 0.0 0.0 0.0 0.2 0.0 0.8 1.6 2.7 0.0 1.3 0.7 1.1 1.0 0.6 0.4 1.6 0.4 0.7 0.0 1.2 0.8 0.7 1.7 0.4 0.2 1.4 0.7 0.2 1.0 1.5 1.2 0.6 1.4 1.5 1.0 1.0 0.7 1.3 1.7 1.5 0.5 0.7 0.5 0.6 0.7 0.5 0.5 0.2 0.3 0.8 0.4 0.5 1.0 0.3 0.4 0.7 0.2 0.3 0.6 1.3 1.4 1.1 0.7 0.1 0.7 0.3 0.2 0.0 1.1 1.7 0.5 0.0 1.1 4.2 0.2 0.4 0.0 0.2 0.0 1.1 0.1 0.0 1.2 0.0 1.3 0.0 0.0 0.1 0.4 0.0 0.0 0.0 54.5 1.0 1.1 0.5 0.0 0.0 6.0 0.0 0.1 0.4 0.5 0.9 1.3 0.1 0.0 0.1 0.1 1.7 4.8 0.1 0.0 0.3 0.3 56.5 0.3 0.3 0.0 1.0 0.1 0.4 0.0 4.0 4.3 0.0 0.0 0.4 0.6 0.0 0.0 0.1 0.0 2.1 0.0 0.5 0.6 0.7 0.2 0.0 0.3 0.1 0.4 0.1 0.1 0.0 SPDYE6 ENSG00000260097 "Speedy/RINGO cell cycle regulator family member E6" P0CI01 7 102345746-102356444 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 5.0" "Cell type enhanced" "Detected in some" "Excitatory neurons: 1.0;Inhibitory neurons: 1.1;Microglial cells: 1.9;Oligodendrocyte precursor cells: 1.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Karpas-707: 5.3" HPA051750 Approved NA NA "Cluster 71: Testis - DNA repair" "Cluster 20: HeLa - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA051750: AB_2681590" "unprognostic (5.47e-2)" "unprognostic (3.61e-1)" "unprognostic (1.66e-1)" "unprognostic (4.89e-3)" "unprognostic (3.45e-1)" "unprognostic (1.23e-2)" "unprognostic (5.84e-3)" "unprognostic (9.81e-2)" "unprognostic (1.36e-2)" "unprognostic (4.09e-2)" "unprognostic (8.22e-3)" "unprognostic (3.49e-2)" "unprognostic (7.81e-6)" "unprognostic (1.57e-1)" "unprognostic (1.61e-1)" "unprognostic (1.73e-1)" "unprognostic (2.12e-1)" 0.8 0.8 0.1 1.3 0.4 1.0 0.7 1.1 0.4 0.7 0.3 1.1 0.7 0.9 0.0 1.2 0.7 0.1 1.2 0.2 0.0 1.3 1.0 1.1 1.4 0.2 0.1 0.9 1.7 0.0 1.2 0.2 0.2 1.2 0.0 0.6 1.2 0.0 2.4 1.2 1.6 0.0 0.0 1.9 1.1 5.0 0.5 0.0 1.4 0.0 0.0 0.9 1.0 0.7 1.2 0.1 0.7 0.7 0.0 0.0 1.5 1.7 0.0 0.0 0.0 0.4 1.2 1.7 0.7 0.0 0.1 1.0 0.0 0.0 0.0 0.6 1.1 1.1 2.9 0.2 0.0 1.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.2 5.3 0.0 1.2 0.7 1.3 0.7 0.2 0.1 1.4 0.2 1.7 0.0 1.4 0.8 0.5 1.8 0.9 0.5 1.1 0.4 0.8 0.5 2.0 1.1 0.9 1.0 1.2 0.9 1.2 0.4 1.3 0.7 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.4 1.1 0.4 0.2 0.0 0.2 0.1 0.2 0.0 0.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 1.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SPEF2 "CT122, FLJ23577, KPL2" ENSG00000152582 "Sperm flagellar 2" Q9C093 5 35617844-35814611 "Disease related genes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 104.6;Endometrial ciliated cells: 143.9;Excitatory neurons: 62.9;Respiratory ciliated cells: 238.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "gdT-cell: 3.2;MAIT T-cell: 3.9;memory CD4 T-cell: 1.9;memory CD8 T-cell: 3.4;naive CD4 T-cell: 2.1;naive CD8 T-cell: 2.6;NK-cell: 3.0" "Group enriched" "Detected in many" 8 "NK-cells: 3.0;T-cells: 3.9" "Cell line enhanced" "Detected in many" "HDLM-2: 13.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039606, HPA040343" Enhanced NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 44: HDLM-2 - Immune response" "Cluster 49: Ciliated cells - Cilium organization" "HPA039606: AB_10671044, HPA040343: AB_2676930" "unprognostic (3.81e-2)" "unprognostic (3.17e-1)" "unprognostic (6.23e-2)" "unprognostic (8.71e-2)" "unprognostic (4.55e-2)" "unprognostic (8.23e-2)" "unprognostic (8.11e-4)" "unprognostic (1.23e-1)" "unprognostic (2.35e-1)" "unprognostic (9.96e-2)" "unprognostic (1.01e-4)" "unprognostic (4.50e-2)" "unprognostic (6.34e-3)" "unprognostic (1.53e-2)" "unprognostic (1.63e-1)" "unprognostic (2.52e-2)" "unprognostic (2.12e-2)" 1.5 3.7 2.9 1.1 3.6 1.5 5.4 1.4 3.1 13.2 20.7 1.8 0.9 11.1 7.6 1.1 15.8 3.1 1.8 2.8 3.6 7.7 1.4 4.6 1.6 5.5 6.3 5.6 4.4 8.6 6.4 4.8 4.6 4.0 2.0 10.2 3.3 4.5 0.4 1.2 1.5 4.3 4.4 2.4 2.2 7.0 4.6 2.1 8.6 0.5 0.9 2.4 5.0 2.8 0.8 1.3 1.6 4.2 1.0 1.2 0.1 2.1 1.2 4.7 3.1 0.0 2.2 0.0 1.1 2.8 5.2 0.1 1.3 1.9 4.6 13.3 0.4 0.0 6.2 0.4 1.3 3.5 0.0 1.8 3.4 2.6 1.4 5.7 0.1 0.8 1.6 0.8 0.8 2.3 0.0 0.0 0.1 3.1 1.2 3.1 0.0 0.0 3.3 0.4 0.1 1.2 0.0 2.4 0.4 0.9 7.5 6.7 0.0 1.3 1.8 2.7 0.7 0.0 0.0 0.3 3.8 0.1 0.0 0.0 0.3 0.0 3.2 0.3 3.9 0.2 1.9 3.4 0.4 0.3 2.1 2.6 0.3 3.0 0.1 0.1 0.5 0.8 2.9 3.6 1.4 3.1 2.8 3.6 5.5 6.3 4.6 4.4 4.6 2.8 2.4 9.6 6.4 36.9 1.1 1.7 2.4 4.7 3.4 15.6 9.2 10.0 6.7 11.5 28.8 5.5 37.5 1.7 3.1 1.5 5.9 4.7 104.6 143.9 23.3 5.2 2.4 6.5 62.9 1.7 0.8 9.7 1.1 9.1 5.7 6.7 5.3 1.3 1.2 20.2 27.6 3.5 8.2 0.8 1.4 25.2 10.2 2.3 1.8 6.5 21.7 13.7 4.1 16.1 11.5 1.2 1.5 7.2 0.7 1.6 0.5 14.2 238.4 41.9 0.0 9.4 5.6 36.1 11.9 0.7 1.0 0.8 9.2 9.0 3.1 0.2 SPEM3 ENSG00000283439 "SPEM family member 3" A0A1B0GUW6 17 7428857-7432820 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 564 "testis: 56.3" "Cell type enriched" "Detected in single" 18 "Distal tubular cells: 1.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 39: Non-specific - Basic cellular processes" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 56.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SPESP1 SP-ESP ENSG00000258484 "Sperm equatorial segment protein 1" Q6UW49 15 68818221-68946811 "Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "testis: 73.2" "Group enriched" "Detected in many" 4 "Early spermatids: 400.4;Spermatocytes: 455.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BJ hTERT+ SV40 Large T+: 17.8;BJ hTERT+ SV40 Large T+ RasG12V: 18.6;HBF TERT88: 21.7;HMC-1: 13.4;OE19: 15.9;RPTEC TERT1: 26.8;SCLC-21H: 19.9;WM-115: 31.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA045936, HPA051040" Enhanced Approved Nucleoplasm,Vesicles,Cytosol "Secreted in male reproductive system" NA NA 52000 "Cluster 46: Basophils - DNA binding" "Cluster 83: Testis - Spermatogenesis" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Vesicles" Cytosol "HPA045936: AB_2679504, HPA051040: AB_2681322" "unprognostic (1.14e-1)" "unprognostic (1.43e-1)" "unprognostic (1.73e-3)" "unprognostic (9.82e-2)" "unprognostic (1.59e-1)" "unprognostic (1.42e-2)" "unprognostic (1.06e-1)" "unprognostic (5.96e-2)" "unprognostic (2.79e-1)" "unprognostic (2.40e-1)" "unprognostic (8.99e-2)" "unprognostic (1.10e-2)" "unprognostic (1.16e-2)" "unprognostic (2.68e-2)" "unprognostic (1.15e-1)" "unprognostic (1.75e-1)" "unprognostic (9.67e-2)" 2.3 3.4 1.1 0.8 1.1 0.4 2.2 1.2 1.6 1.2 1.0 1.6 1.2 1.5 6.3 2.6 1.8 3.5 3.1 1.1 1.2 2.0 1.2 1.1 0.8 1.3 1.2 3.4 1.9 4.7 1.2 12.9 1.3 3.5 1.1 2.8 1.8 2.9 1.6 1.0 0.9 1.2 1.3 1.3 1.5 73.2 1.1 0.9 1.9 1.9 0.7 2.4 0.8 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 17.8 18.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 21.7 5.0 0.0 0.0 0.0 0.0 6.3 0.0 13.4 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 2.9 0.0 0.0 3.3 15.9 0.0 0.0 1.4 0.0 26.8 0.2 19.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 11.6 0.0 0.0 0.0 0.0 0.0 0.0 31.6 1.1 1.3 0.4 0.2 1.1 0.5 0.5 0.4 0.3 0.8 0.3 0.3 0.5 0.5 0.2 0.8 0.4 0.4 0.5 1.1 1.1 1.2 1.6 1.1 1.2 1.3 1.2 1.3 1.3 1.1 1.6 5.1 0.0 0.0 0.0 0.2 1.9 3.0 23.7 1.8 1.0 2.7 4.1 4.1 1.5 4.0 7.3 4.2 92.3 0.3 0.2 1.9 2.1 400.4 3.9 3.4 3.6 1.8 0.8 0.0 2.7 7.2 5.5 0.0 2.0 0.0 1.7 2.2 1.8 7.8 0.0 0.0 0.9 6.1 2.1 3.3 90.3 21.1 1.2 5.4 0.0 1.0 5.3 0.0 0.0 0.0 0.9 0.0 8.6 0.0 3.3 0.0 3.9 6.3 5.6 46.0 3.4 4.2 455.0 88.7 1.1 2.3 62.1 0.5 11.1 0.2 1.5 SPG11 "ALS5, FLJ21439, KIAA1840" ENSG00000104133 "SPG11 vesicle trafficking associated, spatacsin" Q96JI7 15 44562696-44663678 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Amyotrophic lateral sclerosis, Charcot-Marie-Tooth disease, Hereditary spastic paraplegia, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 121.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040412, HPA040947" Approved Supported "Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 52: Non-specific - Transcription" "Plasma membrane, Cytosol" Nucleoli "HPA040412: AB_10795418, HPA040947: AB_10796232" "unprognostic (1.10e-1)" "unprognostic (1.74e-1)" "unprognostic (2.39e-1)" "unprognostic (1.98e-3)" "unprognostic (1.99e-1)" "unprognostic (9.31e-2)" "unprognostic (2.91e-1)" "unprognostic (2.32e-1)" "unprognostic (6.71e-2)" "unprognostic (2.26e-3)" "unprognostic (2.58e-2)" "unprognostic (9.19e-2)" "prognostic favorable (6.28e-5)" "unprognostic (8.73e-2)" "unprognostic (2.48e-1)" "unprognostic (3.72e-1)" "unprognostic (6.06e-2)" 21.1 27.1 18.4 18.2 25.7 27.4 21.6 24.4 21.3 21.5 23.9 25.6 17.1 17.9 25.3 25.6 20.2 16.1 25.5 17.5 22.2 25.0 29.8 24.8 28.4 23.8 22.1 21.4 28.6 26.7 21.3 14.9 23.9 25.3 19.9 30.5 24.7 15.0 22.9 30.4 30.1 12.7 19.1 43.0 26.0 25.5 24.6 23.7 30.9 14.3 18.6 23.8 22.6 33.4 13.2 8.8 21.9 21.6 33.7 33.0 15.8 13.4 17.4 13.0 16.6 10.8 12.5 9.7 16.5 18.2 22.5 29.0 15.1 20.8 12.5 29.3 9.0 22.1 21.1 16.4 23.7 22.2 19.2 25.3 23.3 10.7 30.5 20.4 18.6 16.6 28.8 24.2 18.6 11.5 10.1 19.7 11.5 40.3 11.6 12.9 18.5 10.6 28.0 33.6 14.2 16.8 14.6 23.3 13.1 18.0 22.0 30.2 19.9 17.1 8.5 21.4 16.5 23.8 22.6 19.2 17.6 28.8 17.9 5.7 7.7 11.8 6.5 9.2 6.9 10.0 5.4 4.9 6.2 11.3 4.3 5.3 11.6 6.2 12.4 6.3 6.1 3.7 18.4 25.7 24.4 21.3 17.5 22.2 23.8 22.1 23.9 19.1 24.6 33.4 21.0 44.8 22.2 56.2 40.4 9.3 15.6 18.8 14.2 25.1 19.0 12.6 20.1 18.6 31.3 27.6 47.9 16.5 30.1 29.3 5.9 21.3 28.2 31.7 23.2 17.6 20.0 22.3 62.9 16.9 10.1 19.3 37.2 33.6 27.3 31.9 21.8 23.5 20.1 16.8 68.1 31.2 26.4 43.3 23.5 33.2 17.7 40.4 14.2 74.9 88.1 14.0 50.4 68.3 121.4 17.7 24.0 13.9 21.4 19.3 30.8 14.9 53.6 21.7 6.6 24.8 16.3 51.7 31.6 20.1 11.1 9.3 29.5 24.4 27.3 22.2 SPINK2 HUSI-II ENSG00000128040 "Serine peptidase inhibitor Kazal type 2" P20155 4 56809860-56821742 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 15 "epididymis: 5310.4" "Group enriched" "Detected in many" 10 "Early spermatids: 1217.2;Late spermatids: 1399.4;Spermatocytes: 1989.6" "Group enriched" "Detected in some" 5 "lung cancer: 1.3;testis cancer: 4.6;thyroid cancer: 2.4" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 7 "NK-cell: 146.4" "Lineage enriched" "Detected in many" 7 "NK-cells: 146.4" "Cell line enriched" "Detected in some" 4 "U-266/70: 90.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB020824, HPA026813" Enhanced "Secreted to blood" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "CAB020824: , HPA026813: AB_1857446" "unprognostic (5.56e-3)" "unprognostic (3.60e-1)" "unprognostic (7.54e-2)" "unprognostic (2.35e-2)" "unprognostic (1.54e-1)" "unprognostic (1.60e-1)" "prognostic favorable (2.82e-4)" "unprognostic (9.83e-2)" "unprognostic (6.62e-2)" "unprognostic (9.40e-3)" "unprognostic (2.06e-1)" "unprognostic (2.49e-1)" "unprognostic (4.10e-3)" "unprognostic (3.18e-2)" "unprognostic (2.19e-2)" "unprognostic (3.87e-2)" 0.5 0.1 0.1 1.1 0.2 13.5 1.3 0.1 0.6 1.3 1.8 2.8 1.9 0.3 5310.4 0.2 0.3 0.1 7.4 0.2 0.2 0.3 0.2 0.2 4.7 0.3 0.3 0.4 0.1 0.0 4.2 0.0 0.2 3.5 2.1 0.0 2.0 240.7 1.8 0.5 3.1 0.3 0.2 1.7 3.0 346.1 0.3 3.9 0.6 2.3 4.8 0.5 4.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 21.4 0.0 0.0 0.0 0.0 1.2 0.1 0.1 0.0 2.5 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.6 0.0 0.0 0.0 0.7 2.9 18.0 0.5 0.0 0.0 0.0 0.0 4.5 0.0 6.0 0.3 3.0 0.0 0.0 0.2 0.7 0.0 0.4 0.0 0.0 0.0 0.2 0.0 90.5 0.4 0.0 0.0 0.0 0.0 4.4 0.0 1.1 0.5 0.1 0.6 9.1 5.1 5.4 1.4 10.5 11.1 21.6 0.9 146.4 0.0 0.8 0.3 5.4 0.1 0.2 0.1 0.6 0.2 0.2 0.3 0.3 0.2 0.2 0.3 0.1 0.2 0.0 0.0 0.0 7.2 2.0 14.2 1.8 1.8 0.0 0.2 0.6 3.4 0.0 0.2 0.0 0.0 0.0 2.5 1.4 0.0 0.0 1217.2 0.2 0.1 1.6 1.8 32.4 0.3 0.0 0.3 0.8 0.5 0.2 1.3 0.3 0.0 0.0 0.1 0.0 0.2 10.4 0.0 0.0 3.6 1399.4 37.9 2.5 12.4 0.0 1.6 1.5 1.0 0.0 0.1 0.0 13.1 24.5 35.2 9.5 0.4 0.3 0.3 0.0 13.1 0.4 1.9 1989.6 149.9 0.1 0.3 0.0 16.8 0.0 2.6 2.6 SPINT1 "HAI, MANSC2" ENSG00000166145 "Serine peptidase inhibitor, Kunitz type 1" O43278 15 40844018-40858207 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 255.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1254.0;Distal enterocytes: 477.6;Proximal enterocytes: 514.5;Syncytiotrophoblasts: 1673.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 323.2;HaCaT: 377.6;hTCEpi: 264.0;RT4: 308.2;SK-BR-3: 558.8;T-47d: 267.7" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA006903, HPA031178" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" NA NA 7400000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" "Plasma membrane, Cytosol" Nucleoplasm "HPA006903: AB_1079038, HPA031178: AB_2732463" "prognostic unfavorable (6.97e-4)" "unprognostic (1.00e-3)" "unprognostic (3.00e-3)" "unprognostic (5.03e-2)" "unprognostic (6.06e-2)" "unprognostic (3.19e-1)" "unprognostic (5.94e-2)" "unprognostic (6.04e-2)" "unprognostic (8.24e-3)" "unprognostic (1.46e-2)" "unprognostic (1.09e-3)" "unprognostic (1.01e-1)" "prognostic favorable (1.37e-7)" "unprognostic (5.37e-2)" "unprognostic (2.22e-1)" "unprognostic (6.45e-3)" "unprognostic (2.17e-2)" 2.8 0.7 0.9 16.4 1.5 1.4 34.7 5.0 1.3 42.8 6.4 108.7 159.9 13.2 78.9 255.5 33.6 38.0 1.3 0.9 2.0 79.9 3.5 47.6 6.4 2.8 3.2 2.4 69.2 132.9 31.4 144.9 2.2 52.3 89.2 0.4 162.7 31.4 0.6 148.9 138.2 4.3 1.7 6.9 88.3 1.8 3.2 9.9 34.7 0.4 45.5 57.1 90.1 2.3 124.8 1.0 0.0 0.9 0.1 0.0 323.2 2.3 3.0 4.0 2.4 195.3 202.4 0.3 141.2 0.4 3.6 377.6 30.8 181.9 2.4 1.0 10.6 5.6 3.3 10.8 2.2 21.9 93.9 0.3 264.0 3.9 16.5 3.4 14.7 12.1 2.7 1.1 0.2 96.5 0.9 16.6 37.4 207.6 17.7 12.6 0.0 24.9 179.3 308.2 79.8 3.9 9.3 558.8 15.7 56.9 267.7 16.1 0.0 0.2 2.0 1.2 0.5 1.2 24.5 0.8 0.8 16.3 1.1 0.0 19.7 14.3 0.4 15.9 0.8 8.4 3.0 1.4 32.4 6.0 1.1 0.3 25.9 5.5 18.1 4.0 0.5 7.6 0.9 1.5 5.0 1.3 0.9 2.0 2.8 3.2 2.2 1.7 3.2 2.3 0.8 57.7 14.7 0.0 7.6 76.0 96.7 220.0 55.8 0.1 96.2 63.5 0.5 105.8 207.3 134.3 0.0 1254.0 1.4 477.6 25.4 429.4 0.8 63.3 14.2 6.9 147.3 4.8 0.5 255.1 105.1 10.4 106.5 155.6 10.2 1.9 0.4 0.5 135.4 0.0 0.5 169.4 221.8 10.0 23.8 1.1 3.7 19.8 14.2 0.0 68.6 0.0 0.0 0.0 0.0 309.8 375.2 0.0 2.1 135.7 514.5 44.2 46.6 0.3 0.0 0.1 12.6 0.6 5.9 93.2 87.9 1673.8 6.6 0.1 182.7 222.3 SPNS2 SLC62A2 ENSG00000183018 "Sphingolipid transporter 2" Q8IVW8 17 4498881-4539035 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 51.0" "Cell type enhanced" "Detected in many" "Adipocytes: 32.7;Endothelial cells: 34.5;Microglial cells: 37.5;Oligodendrocytes: 97.8;Urothelial cells: 39.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 31.0;RPTEC TERT1: 161.7;SK-BR-3: 76.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068717 Uncertain NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA068717: AB_2686021" "unprognostic (3.03e-2)" "unprognostic (4.76e-2)" "unprognostic (8.08e-2)" "unprognostic (3.53e-2)" "unprognostic (2.78e-1)" "unprognostic (6.30e-3)" "unprognostic (1.10e-3)" "unprognostic (2.33e-1)" "unprognostic (1.70e-1)" "unprognostic (1.63e-3)" "unprognostic (2.99e-2)" "unprognostic (2.98e-2)" "unprognostic (4.48e-2)" "unprognostic (2.20e-2)" "unprognostic (1.68e-1)" "unprognostic (2.19e-2)" "unprognostic (6.89e-2)" 17.3 2.6 13.1 5.2 14.0 7.9 14.7 13.1 18.2 14.6 0.1 6.5 12.2 8.6 0.6 51.0 7.8 12.1 10.7 14.1 12.1 28.6 3.8 28.3 4.9 26.4 16.2 1.8 10.0 1.1 2.1 7.9 28.9 5.3 2.1 0.6 16.5 2.0 4.4 24.8 10.8 4.8 13.9 11.4 21.0 1.3 15.5 1.7 8.5 3.9 13.3 6.6 22.6 25.1 9.7 1.2 0.0 0.2 0.0 0.0 31.0 0.0 0.0 0.0 0.0 0.5 8.1 0.5 11.8 0.0 0.1 0.5 0.0 0.7 0.0 0.1 0.2 0.6 0.2 0.0 0.1 3.0 0.0 0.0 0.2 0.0 0.0 0.0 4.2 4.7 0.0 0.0 0.0 3.8 0.2 17.0 0.1 17.6 0.3 0.8 0.0 0.3 161.7 0.5 5.4 0.2 0.0 76.7 0.0 5.1 2.7 7.5 0.2 0.2 0.7 0.3 0.1 0.3 0.3 0.1 0.0 8.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 13.1 14.0 13.1 18.2 14.1 12.1 26.4 16.2 28.9 13.9 15.5 25.1 32.7 6.4 10.6 1.6 0.2 1.8 0.4 2.1 0.0 1.2 4.3 3.6 1.2 22.8 16.2 22.0 0.0 1.3 0.2 2.8 1.9 16.7 0.2 0.5 1.0 34.5 0.0 3.2 23.4 3.0 30.5 1.7 26.0 2.8 0.0 0.0 12.5 6.7 1.1 6.7 26.2 12.7 2.0 0.3 1.6 0.2 0.6 1.9 1.8 37.5 0.0 0.4 0.0 3.5 97.8 18.6 0.0 0.4 1.2 11.7 1.9 24.3 16.9 1.1 0.0 1.4 3.1 0.6 0.5 0.6 2.4 1.9 1.6 0.1 1.1 39.8 SPO11 "CT35, SPATA43, TOPVIA" ENSG00000054796 "SPO11 initiator of meiotic double stranded breaks" Q9Y5K1 20 57329803-57343994 "Enzymes, Plasma proteins, Predicted intracellular proteins" Meiosis "DNA-binding, Hydrolase, Isomerase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 85 "testis: 8.5" "Cell type enriched" "Detected in some" 9 "Spermatocytes: 98.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 98.2 10.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SPOCD1 "FLJ25348, PPP1R146" ENSG00000134668 "SPOC domain containing 1" Q6ZMY3 1 31790422-31816051 "Predicted intracellular proteins" "Differentiation, RNA-mediated gene silencing, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.8;testis: 9.7;urinary bladder: 9.5" "Cell type enhanced" "Detected in some" "Hofbauer cells: 13.2;Pancreatic endocrine cells: 30.9;Smooth muscle cells: 10.4;Spermatogonia: 13.1;Urothelial cells: 48.6" "Group enriched" "Detected in many" 7 "glioma: 13.9;urothelial cancer: 5.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 49.9;hTEC/SVTERT24-B: 51.5;RT4: 89.2;TIME: 46.2;U-87 MG: 84.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA031713, HPA031714, HPA031715" Enhanced Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "Nucleoplasm, Nucleoli" "HPA031713: AB_10604099, HPA031714: AB_2674007, HPA031715: AB_2674008" "unprognostic (7.78e-2)" "unprognostic (2.58e-2)" "unprognostic (1.85e-3)" "unprognostic (2.70e-3)" "unprognostic (1.29e-2)" "unprognostic (1.56e-2)" "unprognostic (2.15e-3)" "unprognostic (2.60e-2)" "unprognostic (3.51e-1)" "unprognostic (2.18e-1)" "unprognostic (3.01e-2)" "unprognostic (3.00e-1)" "unprognostic (0.00e+0)" "unprognostic (1.97e-1)" "unprognostic (1.06e-1)" "unprognostic (1.54e-2)" "prognostic favorable (4.05e-5)" 3.0 0.4 1.1 3.1 1.8 0.1 1.6 1.1 4.0 3.0 2.5 0.4 0.9 2.2 0.3 0.3 1.1 0.9 0.2 1.2 1.8 0.5 0.1 7.3 0.1 7.6 2.9 0.3 0.0 0.0 1.5 0.3 4.2 1.6 0.5 0.0 0.3 0.1 0.1 0.3 0.9 1.4 1.6 1.9 0.9 9.7 11.8 0.2 0.3 0.0 0.0 9.5 0.9 3.1 29.8 0.8 0.1 0.1 0.5 4.0 1.4 37.7 49.9 35.8 23.7 0.5 1.7 0.5 5.0 42.7 14.7 3.9 0.0 0.7 11.2 0.1 0.1 0.0 5.8 0.2 1.7 0.0 0.6 17.7 0.6 51.5 1.7 28.9 24.4 2.0 0.7 0.6 21.5 0.1 0.2 0.0 0.7 0.4 0.8 0.0 3.8 0.0 0.1 89.2 0.0 0.0 0.9 0.2 2.6 1.2 21.6 0.0 46.2 37.4 3.9 24.6 14.3 0.2 0.3 0.1 84.6 0.0 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 3.1 1.1 1.8 1.1 4.0 1.2 1.8 7.6 2.9 4.2 1.6 11.8 3.1 0.2 0.0 3.7 0.3 0.0 0.1 6.5 4.5 0.0 0.0 0.3 0.1 0.5 0.0 1.7 0.0 0.0 0.2 0.0 0.0 0.0 8.3 0.3 1.7 0.6 2.3 1.8 0.0 0.4 9.8 0.6 1.0 0.0 5.9 1.3 0.2 0.4 0.0 13.2 0.0 0.1 0.0 0.0 0.6 0.2 0.5 0.0 5.7 0.0 0.0 0.1 0.0 0.0 0.0 1.6 30.9 0.0 0.4 0.1 2.5 0.0 0.1 0.3 0.0 0.0 5.1 10.4 0.0 13.1 0.0 0.0 0.3 0.4 0.1 0.0 48.6 SPOCK2 "KIAA0275, testican-2" ENSG00000107742 "SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2" Q92563 10 72059034-72089032 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 220.1;lymphoid tissue: 114.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 288.4;Bipolar cells: 116.5;dendritic cells: 86.4;Inhibitory neurons: 81.1;Microglial cells: 75.9;NK-cells: 90.6;T-cells: 195.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 117.5;MAIT T-cell: 198.8;memory CD4 T-cell: 115.9;memory CD8 T-cell: 93.5;naive CD4 T-cell: 87.8;naive CD8 T-cell: 89.4;T-reg: 174.3" "Lineage enriched" "Detected in all" 8 "T-cells: 198.8" "Group enriched" "Detected in some" 7 "Hep G2: 50.2;SCLC-21H: 68.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044605 Enhanced "Secreted to blood" NA NA 34000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 24: Non-specific - Transcription regulation" "HPA044605: AB_10965991" "prognostic favorable (4.05e-4)" "unprognostic (3.11e-3)" "unprognostic (2.92e-2)" "unprognostic (2.29e-1)" "unprognostic (2.77e-2)" "prognostic favorable (1.95e-5)" "unprognostic (4.18e-2)" "unprognostic (9.04e-2)" "prognostic favorable (4.72e-4)" "prognostic unfavorable (7.19e-4)" "unprognostic (4.53e-3)" "unprognostic (2.29e-1)" "unprognostic (1.46e-3)" "unprognostic (5.59e-2)" "unprognostic (5.49e-2)" "unprognostic (3.19e-3)" "unprognostic (2.24e-2)" 9.4 46.6 152.6 44.5 108.0 58.1 3.8 160.4 143.2 4.2 2.8 7.6 9.2 4.0 3.1 3.3 6.2 15.3 10.0 117.4 150.1 68.0 2.7 86.5 67.3 212.1 157.7 7.1 1.6 2.0 44.0 3.4 220.1 4.7 5.4 33.4 3.3 5.6 5.1 1.8 32.3 4.4 127.9 29.1 13.6 25.1 207.3 114.4 10.4 6.7 45.3 9.9 3.8 95.6 0.2 0.4 0.3 0.6 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.3 8.2 0.3 1.4 0.0 0.0 0.9 0.0 0.0 0.0 0.5 0.8 0.2 1.4 50.2 1.6 0.4 1.2 0.1 0.4 0.0 0.0 0.2 0.1 2.7 0.1 0.8 0.0 0.3 0.9 0.3 0.1 0.0 0.2 0.2 0.3 0.1 0.0 0.3 68.2 4.1 0.1 1.5 0.4 0.3 0.0 1.9 0.2 0.0 0.3 0.3 0.1 0.7 1.7 7.3 0.3 0.1 0.2 0.6 0.4 0.2 117.5 1.2 198.8 23.6 115.9 93.5 0.3 18.3 87.8 89.4 13.5 14.4 0.4 3.5 174.3 48.4 152.6 108.0 160.4 143.2 117.4 150.1 212.1 157.7 220.1 127.9 207.3 95.6 17.3 288.4 10.0 51.9 54.6 3.8 0.4 2.1 0.0 116.5 1.9 2.0 3.1 1.5 4.1 14.7 6.2 0.1 86.4 2.4 0.0 3.6 8.1 2.5 1.0 29.9 4.9 3.6 39.6 0.8 0.1 8.4 3.6 1.0 3.8 0.2 7.9 0.4 0.2 3.3 81.1 1.3 2.0 1.6 7.9 10.5 5.3 5.5 5.4 75.9 4.1 5.0 90.6 28.6 8.3 0.0 4.4 6.0 34.2 0.5 0.1 0.5 2.4 17.6 0.0 17.9 2.4 6.3 1.1 0.5 4.4 0.4 195.1 0.8 0.7 0.3 SPRR4 ENSG00000184148 "Small proline rich protein 4" Q96PI1 1 152970648-152972574 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "skin 1: 145.4" "Cell type enriched" "Detected in some" 4 "Late spermatids: 54.2" "Cancer enriched" "Detected in many" 5 "head and neck cancer: 17.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA055963 Enhanced Approved "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 61: Skin - Cornification" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "Nuclear membrane" "HPA055963: AB_2682988" "unprognostic (4.40e-2)" "unprognostic (7.38e-3)" "unprognostic (1.45e-1)" "unprognostic (6.75e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 145.4 0.0 0.0 0.0 0.0 0.0 7.4 0.0 0.9 0.0 0.0 0.1 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SPRY1 hSPRY1 ENSG00000164056 "Sprouty RTK signaling antagonist 1" O43609 4 123396795-123403760 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 238.1" "Cell type enhanced" "Detected in many" "Adipocytes: 771.3;Endothelial cells: 352.8;Fibroblasts: 222.3;Leydig cells: 448.0;Skeletal myocytes: 245.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 61.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 95.4;AN3-CA: 194.1;ASC diff: 76.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013538, HPA051369, HPA070554" Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus, Cytosol" Nucleoplasm "CAB013538: AB_2533452, HPA051369: AB_2681457, HPA070554: AB_2686280" "unprognostic (1.27e-1)" "unprognostic (9.08e-2)" "unprognostic (2.06e-1)" "unprognostic (7.15e-2)" "unprognostic (5.33e-2)" "unprognostic (2.19e-2)" "unprognostic (1.36e-1)" "unprognostic (9.43e-2)" "unprognostic (6.99e-2)" "unprognostic (4.32e-1)" "unprognostic (4.06e-1)" "unprognostic (3.11e-2)" "unprognostic (8.77e-3)" "unprognostic (1.21e-3)" "unprognostic (4.48e-2)" "unprognostic (1.54e-2)" "unprognostic (1.27e-1)" 238.1 38.4 6.5 22.3 7.9 22.7 154.3 7.6 9.0 71.9 26.6 46.6 15.7 40.9 24.1 42.5 81.2 83.8 73.1 7.5 8.4 35.6 21.5 58.3 13.0 5.5 5.4 30.0 31.8 37.4 27.3 49.6 5.8 52.0 27.5 19.0 45.2 24.7 49.9 79.8 25.2 57.7 5.6 17.0 35.1 10.2 7.6 29.2 92.7 49.9 10.1 74.4 71.0 6.0 6.3 1.8 95.4 194.1 76.5 51.6 6.4 0.4 4.9 0.3 2.0 5.8 10.3 0.0 42.4 2.9 0.4 1.2 2.6 4.6 0.7 0.1 10.0 2.2 0.0 31.0 21.7 14.2 0.1 21.1 2.5 0.7 2.1 10.5 8.1 2.2 1.7 1.9 4.7 0.7 16.4 34.8 22.8 22.6 32.0 7.1 10.3 0.2 13.2 14.5 14.5 12.3 0.1 19.4 19.6 10.1 1.9 0.0 20.2 1.2 0.2 0.4 2.9 1.0 0.1 0.2 1.4 2.6 3.2 0.1 0.4 6.5 1.1 0.2 33.1 29.8 4.0 9.2 0.1 61.2 5.7 6.4 0.4 14.2 0.1 1.7 0.0 2.0 6.5 7.9 7.6 9.0 7.5 8.4 5.5 5.4 5.8 5.6 7.6 6.0 771.3 28.9 28.3 14.4 16.2 49.6 17.3 37.3 68.9 86.2 22.8 69.6 16.9 32.9 20.6 27.6 33.3 12.7 21.6 10.4 80.3 5.0 2.5 45.9 41.9 352.8 26.5 5.7 5.0 10.9 1.7 222.3 8.2 67.4 9.5 0.2 166.3 5.9 10.1 6.7 2.2 15.0 14.2 15.3 37.9 10.5 448.0 17.1 46.2 5.6 0.7 158.3 0.0 7.5 0.3 7.0 6.3 57.9 6.1 16.8 8.1 38.7 11.7 84.5 151.2 245.0 81.6 6.2 9.6 37.0 43.3 3.1 57.3 1.8 17.9 13.5 SPTB ENSG00000070182 "Spectrin beta, erythrocytic" P11277 14 64746283-64879907 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Disease variant, Elliptocytosis, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 62.5;skeletal muscle: 123.9;tongue: 69.8" "Cell type enhanced" "Detected in some" "Erythroid cells: 81.0;Excitatory neurons: 16.0;Horizontal cells: 16.8;Inhibitory neurons: 32.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HEL: 39.2;K-562: 47.8;U-937: 14.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003394, HPA003398, CAB015169, CAB016232" Enhanced Approved Cytosol NA NA 7800000 "Cluster 80: Striated muscle - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 37: Myocytes - Muscle contraction" Cytosol "CAB015169: AB_2194363, CAB016232: AB_785785, HPA003394: AB_1080076, HPA003398: AB_1080074" "unprognostic (2.69e-1)" "unprognostic (4.72e-1)" "unprognostic (3.04e-2)" "unprognostic (2.19e-3)" "unprognostic (1.71e-1)" "unprognostic (2.33e-2)" "unprognostic (1.49e-1)" "unprognostic (1.30e-3)" "unprognostic (2.66e-1)" "unprognostic (2.28e-2)" "unprognostic (1.55e-3)" "unprognostic (2.11e-1)" "unprognostic (2.65e-1)" "unprognostic (1.39e-2)" "unprognostic (2.97e-1)" "unprognostic (3.44e-2)" "unprognostic (2.18e-2)" 2.2 1.5 5.3 0.2 11.2 62.5 0.3 28.3 11.4 0.3 27.7 0.2 0.1 0.2 5.2 2.0 0.5 0.4 22.7 10.8 4.0 1.0 0.1 0.4 0.0 28.5 5.3 0.2 2.6 11.1 5.3 6.7 28.2 1.5 0.1 1.6 2.2 1.1 123.9 0.2 0.2 0.8 8.5 0.8 0.2 0.7 9.3 0.4 0.1 69.8 0.0 0.2 0.2 4.4 0.3 1.5 0.0 0.0 0.0 0.0 0.1 0.3 0.3 0.1 0.0 0.7 0.0 0.0 0.0 0.3 0.3 2.3 6.3 0.2 0.0 0.4 3.7 39.2 0.3 0.0 0.0 0.0 0.7 0.1 0.1 0.0 0.0 0.0 0.0 1.4 47.8 0.0 0.0 0.3 0.0 0.3 0.0 0.5 2.1 0.0 0.0 0.2 0.0 0.2 6.1 2.6 0.0 0.0 0.0 0.2 0.1 0.5 0.0 0.3 6.7 0.0 0.6 1.5 7.7 0.0 0.1 14.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 5.3 11.2 28.3 11.4 10.8 4.0 28.5 5.3 28.2 8.5 9.3 4.4 0.1 0.0 0.0 0.7 0.0 0.8 0.7 0.6 0.0 10.3 0.5 0.1 6.3 1.5 0.7 0.0 0.0 0.1 0.5 0.0 0.0 0.3 0.4 0.4 0.9 0.4 3.0 81.0 16.0 0.2 0.3 0.8 0.0 0.9 2.5 0.2 0.0 0.0 0.2 16.8 32.1 0.3 0.0 0.0 0.4 0.4 0.3 0.3 1.8 1.9 0.0 5.0 1.0 11.1 2.1 0.3 0.0 1.2 0.1 0.7 0.0 0.2 0.0 2.6 6.6 11.6 3.8 0.1 1.1 0.5 0.4 0.1 0.6 0.4 0.1 0.6 SPTY2D1OS SPTY2D1-AS1 ENSG00000247595 "SPTY2D1 opposite strand" A0A0U1RRN3 11 18588781-18610255 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in many" 34 "testis: 487.5" "Cell type enhanced" "Detected in many" "Breast glandular cells: 7.5;Distal tubular cells: 23.5;Endometrial stromal cells: 6.9;Granulosa cells: 18.4;Proximal tubular cells: 14.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 4.4;HeLa: 7.6;Hep G2: 4.5" "Low region specificity" "Detected in many" "Secreted in male reproductive system" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 83: Testis - Spermatogenesis" "Cluster 20: HeLa - Mitochondria" "Cluster 40: Granulosa cells - Unknown function" "unprognostic (1.07e-1)" "unprognostic (1.24e-1)" "unprognostic (8.60e-3)" "unprognostic (5.14e-2)" "unprognostic (6.61e-2)" "unprognostic (9.32e-2)" "unprognostic (4.44e-7)" "unprognostic (1.75e-1)" "unprognostic (1.39e-2)" "unprognostic (7.83e-2)" "unprognostic (5.36e-2)" "unprognostic (6.50e-3)" "unprognostic (5.41e-4)" "unprognostic (1.14e-1)" "unprognostic (1.10e-1)" "unprognostic (1.91e-1)" "unprognostic (1.48e-2)" 0.9 1.8 1.4 1.4 1.5 0.9 2.7 3.2 2.9 1.7 3.8 1.5 0.2 2.0 3.7 1.3 1.6 1.2 1.5 1.4 2.6 2.0 0.7 0.8 0.7 2.2 1.7 2.4 1.1 0.9 1.6 1.2 1.9 2.0 2.3 3.5 1.7 1.4 1.5 14.1 1.0 1.3 0.9 1.2 0.9 487.5 1.8 0.4 1.7 0.3 0.8 0.9 1.3 2.7 0.5 4.4 1.7 2.3 1.5 2.3 2.1 0.3 0.5 0.9 1.0 3.4 1.2 0.8 0.2 0.4 0.9 0.9 0.0 0.0 0.0 1.3 1.6 0.5 7.6 4.5 0.2 0.6 1.3 0.9 0.3 0.2 1.0 1.1 0.9 0.0 1.2 0.3 0.3 1.6 0.1 1.6 1.2 1.1 2.7 0.1 0.5 0.3 1.8 1.8 0.4 0.2 1.6 0.1 0.0 0.6 0.9 0.0 0.9 1.6 1.3 0.8 0.1 0.0 0.2 0.0 0.6 0.9 1.1 0.2 0.3 0.6 0.2 0.0 0.5 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.5 0.2 0.1 0.1 0.3 0.2 1.4 1.5 3.2 2.9 1.4 2.6 2.2 1.7 1.9 0.9 1.8 2.7 2.8 3.2 3.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 7.5 6.0 0.0 0.0 1.3 5.5 0.0 1.0 1.5 0.0 23.5 3.2 0.0 4.9 6.9 1.1 0.0 0.0 0.0 5.0 1.1 1.8 0.0 3.9 0.0 18.4 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 1.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.1 0.0 0.0 14.3 0.7 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.5 0.8 2.1 0.0 0.0 SQLE ENSG00000104549 "Squalene epoxidase" Q14534 8 124998497-125022283 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018038, HPA020762" Enhanced Uncertain Vesicles,Cytosol NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 37: Intestine - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Vesicles, Cytosol" "HPA018038: AB_2669753, HPA020762: AB_2670512" "unprognostic (1.37e-2)" "unprognostic (6.26e-3)" "unprognostic (5.12e-2)" "unprognostic (9.51e-3)" "unprognostic (4.63e-1)" "prognostic unfavorable (7.42e-4)" "unprognostic (4.76e-3)" "prognostic unfavorable (4.67e-4)" "unprognostic (3.45e-2)" "unprognostic (7.21e-2)" "prognostic unfavorable (2.73e-4)" "unprognostic (7.51e-2)" "prognostic unfavorable (5.70e-4)" "unprognostic (9.71e-2)" "unprognostic (4.62e-2)" "unprognostic (1.19e-3)" "unprognostic (7.74e-3)" 8.6 31.1 17.5 19.6 27.0 23.0 22.1 26.8 24.0 30.7 25.4 21.6 31.0 16.4 9.1 78.7 18.6 10.7 7.2 18.6 24.4 17.1 72.3 30.9 17.7 47.3 27.7 14.3 10.7 22.7 16.5 47.5 35.1 25.0 18.6 17.8 19.1 7.6 1.4 49.4 14.0 12.3 27.6 9.7 21.8 59.4 21.8 14.2 10.5 1.6 29.4 14.7 46.2 34.6 135.5 51.5 301.6 87.2 91.7 154.1 30.5 34.9 106.3 46.5 84.7 70.6 192.3 92.7 49.2 43.2 186.0 101.0 127.3 192.4 53.6 77.1 268.3 265.2 32.6 181.1 134.6 31.5 74.6 106.1 201.4 138.8 113.3 29.8 51.5 64.2 153.8 174.8 38.1 223.7 109.6 39.3 125.2 92.6 35.2 47.5 55.4 126.6 329.3 153.3 93.9 47.6 71.6 226.3 74.1 96.5 60.7 81.3 50.8 19.2 66.0 22.9 31.6 31.6 69.6 126.6 32.0 93.7 33.8 1.5 6.3 0.7 10.6 10.8 5.0 16.6 6.0 9.5 15.2 17.1 8.2 8.6 0.2 12.6 12.7 10.8 7.1 7.7 17.5 27.0 26.8 24.0 18.6 24.4 47.3 27.7 35.1 27.6 21.8 34.6 13.2 60.9 97.9 21.5 34.7 22.9 64.0 199.9 16.5 41.8 35.6 27.3 6.1 31.5 129.6 53.3 50.1 99.7 20.6 81.6 7.9 60.3 21.0 95.9 23.3 39.7 31.7 22.3 14.3 83.6 133.7 35.3 51.0 80.5 41.3 77.1 9.7 127.9 61.1 148.0 18.8 58.0 126.1 10.9 30.1 13.2 23.9 22.2 21.4 13.1 91.0 24.3 8.2 20.1 77.9 98.6 38.4 10.9 30.6 118.0 17.3 3.7 123.0 61.1 26.3 12.5 42.0 179.5 128.6 69.5 89.1 217.1 21.1 171.8 35.0 114.8 SREBF1 "bHLHd1, SREBP-1c, SREBP1, SREBP1a" ENSG00000072310 "Sterol regulatory element binding transcription factor 1" P36956 17 17810399-17837011 "Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 219.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "RPMI-8226: 202.5;SK-BR-3: 178.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005406, HPA043343, HPA043878" Uncertain Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 18: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 30: Mammary glandular cells - Lactation" "Nucleoplasm, Golgi apparatus, Cytosol" "CAB005406: AB_2194226, HPA043343: AB_2678439, HPA043878: AB_2678710" "unprognostic (9.29e-2)" "unprognostic (1.12e-1)" "unprognostic (2.28e-2)" "prognostic favorable (2.66e-4)" "unprognostic (4.50e-2)" "unprognostic (1.05e-2)" "unprognostic (9.85e-2)" "unprognostic (1.15e-1)" "unprognostic (3.14e-2)" "unprognostic (9.02e-3)" "prognostic favorable (9.05e-4)" "unprognostic (3.12e-1)" "unprognostic (9.02e-3)" "unprognostic (1.11e-2)" "unprognostic (1.20e-1)" "unprognostic (7.65e-2)" "unprognostic (2.36e-3)" 42.2 219.2 26.8 7.9 41.5 20.1 46.5 20.4 37.2 51.5 9.4 37.7 28.7 23.4 8.9 68.7 42.7 14.0 27.4 20.0 25.9 24.7 128.5 26.4 9.1 30.1 29.7 41.4 17.0 8.4 37.0 7.8 24.2 37.2 6.7 3.9 89.5 16.7 34.5 47.8 34.0 5.6 23.4 17.2 25.2 35.4 35.8 14.4 27.0 2.9 6.3 32.5 48.8 41.7 54.1 122.5 12.0 85.2 24.9 55.8 23.5 18.5 60.0 16.4 39.2 23.3 104.2 33.5 17.2 14.8 14.5 144.0 16.7 47.2 4.0 21.1 7.2 16.8 86.4 19.1 36.1 2.5 29.6 42.0 19.6 21.8 12.5 12.2 17.6 64.9 36.8 105.8 2.5 118.7 46.9 26.1 17.8 38.3 23.1 32.6 10.8 202.5 9.0 23.1 16.3 70.5 24.4 178.7 48.0 8.9 62.0 32.6 21.5 8.2 40.5 19.5 12.5 32.2 3.1 15.5 48.9 24.6 45.2 0.0 0.3 0.1 0.4 0.1 0.1 0.1 0.2 0.0 0.0 0.1 0.4 0.6 1.3 0.1 0.1 0.1 0.0 0.2 26.8 41.5 20.4 37.2 20.0 25.9 30.1 29.7 24.2 23.4 35.8 41.7 6.1 6.4 26.0 66.9 11.9 9.3 12.0 29.2 14.8 24.5 58.0 30.6 9.4 18.6 29.7 20.2 29.2 4.5 11.4 44.5 1.9 16.5 2.7 30.9 37.2 10.5 29.9 24.8 12.8 23.5 15.7 24.7 31.1 31.9 14.7 13.2 12.8 72.2 12.1 58.9 11.3 30.8 24.4 14.0 13.3 4.9 29.8 15.1 8.8 15.0 11.0 51.7 1.0 10.6 56.7 16.7 20.8 10.9 8.4 19.0 33.2 6.6 32.1 31.6 13.1 15.6 12.9 11.4 4.9 40.2 18.3 19.8 13.4 27.5 41.1 25.2 SRPX2 SRPUL ENSG00000102359 "Sushi repeat containing protein X-linked 2" O60687 X 100644195-100675788 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Cell adhesion" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 31.8" "Cell type enhanced" "Detected in many" "Adipocytes: 20.9;Fibroblasts: 34.3;Granulosa cells: 21.6;Microglial cells: 37.5;Skeletal myocytes: 17.5;Urothelial cells: 49.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 282.3;ASC TERT1: 116.9;HSkMC: 103.3;HUVEC TERT2: 72.7" "Low region specificity" "Detected in many" "Region enhanced" "Detected in single" "spinal cord: 2.8" HPA038786 Approved "Secreted to blood" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA038786: AB_10672724" "unprognostic (4.10e-2)" "unprognostic (4.55e-2)" "unprognostic (2.08e-1)" "unprognostic (3.72e-2)" "unprognostic (1.96e-1)" "unprognostic (4.21e-3)" "unprognostic (3.59e-3)" "unprognostic (5.41e-2)" "unprognostic (3.22e-2)" "unprognostic (1.26e-1)" "unprognostic (2.86e-2)" "unprognostic (2.29e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.84e-3)" "unprognostic (1.69e-1)" "unprognostic (8.67e-2)" "unprognostic (3.85e-1)" 31.8 7.5 3.6 6.3 4.5 0.2 20.7 1.3 2.6 11.3 8.5 7.1 1.2 6.0 0.9 17.7 7.1 3.1 12.7 2.8 5.8 13.9 5.4 13.8 0.4 4.3 5.6 8.3 2.9 0.7 2.5 9.3 3.1 6.3 1.8 0.1 4.6 3.8 3.4 3.7 5.1 4.4 2.0 12.9 4.5 1.1 7.4 0.3 4.3 4.8 1.2 16.8 10.9 2.5 11.7 1.2 2.9 0.1 282.3 116.9 0.0 26.3 19.8 8.0 25.1 1.4 17.6 0.0 1.1 15.9 7.5 0.7 0.2 13.1 8.6 0.1 0.1 0.2 0.9 2.8 29.3 0.2 0.6 103.3 0.3 27.8 0.9 24.6 72.7 0.0 0.0 0.1 27.1 0.0 0.0 0.0 3.4 0.2 0.3 0.0 2.5 0.0 11.4 37.6 0.4 0.0 0.0 0.8 0.2 6.1 0.3 0.1 36.7 13.8 12.3 10.3 0.9 0.1 0.0 0.1 18.3 0.0 8.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 4.5 1.3 2.6 2.8 5.8 4.3 5.6 3.1 2.0 7.4 2.5 20.9 0.0 0.6 10.1 0.3 0.4 5.0 6.5 0.6 0.0 4.8 1.8 0.9 0.0 13.7 0.0 0.0 0.2 0.0 1.9 0.0 1.6 3.6 0.6 11.2 1.6 0.0 0.0 0.4 0.0 0.4 34.3 1.1 0.4 0.0 21.6 4.6 0.2 0.9 0.0 0.2 0.1 4.1 0.3 1.6 2.7 15.8 0.3 0.0 37.5 0.0 0.0 0.0 2.0 0.1 0.8 0.0 6.0 0.2 1.6 0.0 0.1 15.5 0.0 0.0 17.5 14.6 0.2 0.1 0.6 0.4 0.5 0.3 2.6 0.4 49.1 SRR "ILV1, ISO1" ENSG00000167720 "Serine racemase" Q9GZT4 17 2303383-2325260 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Allosteric enzyme, Isomerase, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 23.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007529, CAB015343" Approved Approved Vesicles NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Vesicles "CAB015343: AB_2195009, HPA007529: AB_2667853" "unprognostic (2.96e-1)" "unprognostic (7.86e-2)" "unprognostic (6.01e-2)" "prognostic favorable (6.20e-5)" "unprognostic (3.05e-1)" "unprognostic (1.57e-2)" "unprognostic (4.32e-2)" "unprognostic (9.97e-2)" "unprognostic (9.09e-2)" "unprognostic (4.85e-2)" "prognostic favorable (8.16e-4)" "unprognostic (5.17e-2)" "prognostic favorable (2.45e-6)" "unprognostic (6.14e-2)" "unprognostic (1.99e-1)" "unprognostic (1.89e-1)" "unprognostic (5.84e-2)" 10.5 7.8 11.0 6.6 11.5 13.9 8.9 12.5 13.1 6.8 13.0 9.4 6.9 7.5 10.3 10.9 8.7 8.3 10.9 9.4 13.4 9.0 8.2 6.1 6.6 11.2 12.4 8.4 11.9 12.3 4.9 5.4 12.7 8.4 7.5 16.6 10.7 7.7 15.6 11.8 5.9 7.0 11.1 6.9 8.0 7.1 12.5 9.0 11.8 6.7 5.4 8.4 5.3 11.8 14.8 27.0 42.7 17.9 24.9 24.4 22.8 29.8 20.2 19.4 20.5 25.3 18.1 27.5 4.1 29.1 14.3 30.2 12.2 11.4 24.6 32.6 26.0 14.6 20.3 9.6 22.5 4.3 8.0 22.9 11.5 41.4 21.0 21.2 28.6 28.2 15.2 19.8 43.9 8.4 28.7 5.8 10.0 13.8 19.9 45.5 48.8 13.3 22.9 6.9 9.2 23.4 26.8 3.3 14.3 14.6 20.7 10.3 21.3 21.4 14.7 24.7 19.0 16.7 26.0 5.1 36.9 13.7 29.8 4.3 8.1 5.6 8.8 8.4 9.1 10.1 11.2 9.1 15.6 10.2 9.2 12.1 1.0 15.7 14.0 11.0 8.8 8.5 11.0 11.5 12.5 13.1 9.4 13.4 11.2 12.4 12.7 11.1 12.5 11.8 5.0 3.2 3.7 3.6 2.1 2.9 3.5 17.4 1.8 8.5 5.5 4.6 4.2 1.5 8.4 1.8 0.0 5.9 3.4 3.0 13.7 9.6 1.9 6.6 5.5 5.4 1.8 5.2 3.5 6.6 3.2 5.7 3.6 4.6 0.0 13.2 8.2 3.2 9.3 16.8 4.9 2.5 12.2 4.6 4.9 1.5 4.1 3.7 5.4 4.7 9.3 11.0 5.2 5.0 7.8 6.7 0.8 5.3 6.1 2.9 2.9 6.3 10.2 5.6 0.0 4.6 6.5 23.3 13.1 4.7 2.4 3.4 2.3 9.7 3.5 4.0 SRRM3 FLJ37078 ENSG00000177679 "Serine/arginine repetitive matrix 3" 7 76201896-76287288 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "brain: 56.0;retina: 27.2" "Group enriched" "Detected in many" 7 "Bipolar cells: 153.1;Cone photoreceptor cells: 479.6;Excitatory neurons: 139.1;Horizontal cells: 171.6;Inhibitory neurons: 144.4;Rod photoreceptor cells: 421.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "SCLC-21H: 10.9;SH-SY5Y: 8.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019337 Approved "Plasma membrane,Intermediate filaments,Microtubules" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane" "Intermediate filaments, Microtubules" "HPA019337: AB_1848909" "unprognostic (1.65e-1)" "unprognostic (1.96e-1)" "unprognostic (8.37e-3)" "unprognostic (4.93e-2)" "unprognostic (1.81e-1)" "unprognostic (1.39e-1)" "unprognostic (8.53e-2)" "unprognostic (6.51e-2)" "unprognostic (1.89e-3)" "unprognostic (1.62e-2)" "unprognostic (5.07e-3)" "unprognostic (6.37e-2)" "unprognostic (3.73e-3)" "unprognostic (5.05e-1)" "unprognostic (2.98e-1)" "unprognostic (1.84e-1)" "unprognostic (5.15e-2)" 0.0 2.1 6.0 0.1 13.2 0.0 0.0 56.0 30.7 0.1 0.0 0.3 0.1 0.2 0.2 0.1 0.0 0.0 0.1 4.8 0.2 0.0 0.0 0.0 0.0 41.5 3.2 0.2 0.3 0.3 8.9 0.0 40.1 0.1 0.1 27.2 0.1 0.0 0.1 0.0 0.1 0.0 1.6 0.0 0.4 2.1 0.9 0.0 0.0 0.0 0.0 0.0 0.2 4.7 0.3 0.2 0.1 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.9 8.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 13.2 56.0 30.7 4.8 0.2 41.5 3.2 40.1 1.6 0.9 4.7 0.3 0.0 0.0 8.1 0.0 2.0 6.4 1.9 7.4 153.1 1.8 0.5 6.9 1.5 1.2 0.0 479.6 0.4 0.0 0.2 0.0 2.0 22.2 0.5 4.2 1.2 12.1 0.0 139.1 2.4 8.1 4.8 0.5 1.0 0.0 12.0 1.8 0.0 0.5 171.6 144.4 0.1 2.0 0.0 0.8 32.2 2.1 0.2 3.6 5.6 0.0 15.9 0.0 18.6 4.9 0.9 0.1 2.2 0.0 2.2 0.0 0.4 0.2 421.8 0.0 1.2 2.0 8.6 3.1 4.9 1.1 2.2 0.1 0.2 0.0 4.9 SRRM4 "KIAA1853, nSR100" ENSG00000139767 "Serine/arginine repetitive matrix 4" A7MD48 12 118981541-119163051 "Predicted intracellular proteins" "Differentiation, mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 16 "brain: 18.3;retina: 29.1" "Group enriched" "Detected in some" 11 "Bipolar cells: 330.4;Cone photoreceptor cells: 429.5;Excitatory neurons: 182.0;Inhibitory neurons: 322.2;Rod photoreceptor cells: 372.4" "Cancer enriched" "Detected in single" 7 "glioma: 1.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HeLa: 4.4;SCLC-21H: 3.9;SH-SY5Y: 3.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052783 Uncertain NA NA "Cluster 58: Brain - Synaptic function" "Cluster 20: HeLa - Mitochondria" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA052783: AB_2681945" "unprognostic (2.44e-2)" "unprognostic (2.66e-1)" "unprognostic (2.40e-2)" "unprognostic (1.25e-1)" "unprognostic (1.64e-1)" "unprognostic (1.37e-1)" "unprognostic (1.11e-1)" "unprognostic (1.61e-5)" "unprognostic (1.10e-2)" "unprognostic (1.75e-1)" "unprognostic (5.70e-3)" "unprognostic (2.23e-1)" "unprognostic (6.88e-2)" "unprognostic (1.61e-1)" 0.0 1.1 7.1 0.0 10.4 0.1 0.0 16.4 18.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.5 8.8 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 1.5 0.0 0.1 0.0 0.0 29.1 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.3 1.3 0.0 0.1 0.1 0.0 0.0 0.0 6.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 3.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.1 10.4 16.4 18.3 8.8 0.1 0.0 0.1 0.1 0.0 1.3 6.4 0.0 6.4 0.0 3.6 0.0 0.0 0.1 0.0 0.0 330.4 0.0 0.0 9.9 0.0 0.6 0.0 429.5 0.8 0.0 0.0 0.0 0.0 5.6 10.6 0.9 1.5 0.0 0.0 182.0 0.0 0.3 0.3 0.0 4.3 0.0 0.0 0.0 0.0 0.0 28.6 322.2 0.0 0.0 0.0 0.0 3.8 0.0 0.1 0.0 9.4 0.0 12.1 0.0 5.5 3.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 372.4 6.6 0.2 1.0 0.2 1.2 0.0 0.0 2.3 0.1 0.0 0.0 0.1 SRRM5 ENSG00000226763 "Serine/arginine repetitive matrix 5" B3KS81 19 43596617-43614498 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "testis: 47.8" "Group enriched" "Detected in some" 43 "Early spermatids: 176.5;Late spermatids: 64.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in some" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA047399, HPA052924" Uncertain Approved Vesicles,Centrosome NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 20: HeLa - Mitochondria" "Cluster 29: Early spermatids - Spermatogenesis" Vesicles Centrosome "HPA047399: AB_10963088, HPA052924: " "unprognostic (3.95e-3)" "unprognostic (7.56e-3)" "unprognostic (6.72e-2)" "unprognostic (3.40e-2)" "unprognostic (1.38e-1)" "unprognostic (2.41e-2)" "unprognostic (1.10e-3)" "unprognostic (1.12e-1)" "unprognostic (8.02e-2)" "unprognostic (2.89e-2)" "unprognostic (3.69e-2)" "unprognostic (2.16e-2)" "unprognostic (2.68e-5)" "unprognostic (2.44e-1)" "unprognostic (3.31e-1)" "unprognostic (2.07e-1)" "unprognostic (1.00e-3)" 0.5 0.9 1.0 0.5 1.2 0.4 0.5 2.3 1.3 0.8 0.6 0.8 0.3 0.5 0.3 1.0 0.7 0.4 0.9 0.9 1.0 1.4 1.1 0.6 1.0 1.1 0.9 0.9 1.2 0.2 1.6 0.2 1.1 1.9 0.1 1.9 0.9 0.1 0.5 0.8 0.7 0.1 0.6 0.9 0.7 47.8 1.0 0.1 1.1 0.0 0.0 0.6 0.9 1.2 1.3 1.1 0.4 0.8 0.4 0.3 0.3 0.3 0.1 0.1 0.1 0.7 0.5 0.4 0.7 0.1 0.3 0.8 0.4 0.1 0.2 0.5 0.5 0.4 1.1 0.6 0.1 0.3 0.6 0.3 0.4 0.0 0.1 0.4 0.1 0.6 0.3 1.1 0.0 1.1 0.5 0.5 0.1 0.9 0.3 0.8 0.3 0.3 0.3 1.7 0.8 0.3 0.1 0.4 0.4 0.5 0.9 0.2 0.6 1.1 0.7 0.4 0.6 1.3 0.9 0.5 0.6 0.4 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.2 2.3 1.3 0.9 1.0 1.1 0.9 1.1 0.6 1.0 1.2 0.1 0.0 0.0 0.0 0.1 0.4 0.1 0.1 2.8 0.3 0.3 0.5 0.4 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 176.5 0.3 0.4 0.1 0.0 0.4 0.2 0.0 0.0 0.4 0.0 0.4 0.0 0.7 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.3 64.9 1.2 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.2 0.9 0.0 0.8 0.1 0.7 0.6 0.8 0.3 0.1 0.2 0.3 0.1 0.1 SRSF5 "HRS, SFRS5, SRP40" ENSG00000100650 "Serine and arginine rich splicing factor 5" Q13243 14 69726900-69772005 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043484, HPA056523" Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA 23000 "Cluster 34: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "Nucleoli, Cytosol" "HPA043484: AB_10797143, HPA056523: AB_2683164" "unprognostic (2.08e-3)" "prognostic favorable (7.91e-4)" "unprognostic (1.89e-1)" "unprognostic (1.19e-1)" "unprognostic (1.19e-1)" "unprognostic (1.79e-2)" "unprognostic (1.86e-1)" "unprognostic (2.06e-2)" "unprognostic (3.32e-2)" "unprognostic (1.61e-1)" "unprognostic (9.30e-3)" "unprognostic (1.07e-3)" "unprognostic (2.37e-2)" "unprognostic (1.13e-1)" "unprognostic (1.42e-1)" "unprognostic (2.42e-1)" "unprognostic (1.00e-2)" 210.9 188.4 68.1 149.5 72.5 456.9 229.8 60.3 108.2 174.2 125.9 231.8 129.2 222.5 218.0 217.9 240.9 130.1 154.4 75.9 69.7 119.6 183.8 214.8 210.1 75.5 71.1 220.0 136.6 188.1 215.5 105.1 74.1 172.7 164.8 233.8 235.8 126.7 217.6 282.0 256.6 180.3 66.0 211.8 212.8 104.1 69.5 214.7 224.8 68.3 155.0 189.3 177.4 97.1 456.4 133.5 313.8 141.4 192.7 179.6 177.4 214.6 239.7 177.6 183.7 164.7 283.6 473.1 110.4 301.8 174.7 210.2 242.5 309.2 209.7 407.4 142.3 354.3 386.7 183.6 224.3 334.7 255.7 350.9 201.2 199.7 216.3 260.4 247.0 401.8 255.4 268.3 114.3 382.1 385.1 232.4 182.0 356.6 128.2 324.0 148.5 183.3 237.2 563.1 165.9 236.3 364.3 214.1 296.0 188.5 235.9 292.3 299.7 98.4 264.2 110.9 205.6 261.6 184.5 754.8 232.3 286.1 140.1 137.1 65.8 103.6 93.1 117.9 94.9 109.5 83.1 85.0 70.1 108.7 81.1 79.6 161.9 86.2 129.6 99.8 74.8 77.2 68.1 72.5 60.3 108.2 75.9 69.7 75.5 71.1 74.1 66.0 69.5 97.1 380.7 253.2 309.1 218.1 392.8 138.0 768.6 610.1 204.9 387.4 248.6 259.1 195.0 240.2 386.6 183.9 239.8 444.3 542.9 471.8 320.8 201.7 190.3 224.2 169.8 293.6 302.9 195.4 199.5 171.8 261.5 288.0 188.6 225.3 480.2 251.3 249.9 225.4 217.7 378.6 177.7 376.6 380.5 236.2 154.3 105.0 345.5 314.7 133.4 104.9 323.4 277.4 428.5 128.2 268.7 226.6 538.5 267.1 212.3 376.7 484.7 228.2 373.4 317.3 276.1 583.7 354.2 201.8 149.8 196.4 145.6 749.2 456.6 201.6 275.5 542.1 SRY TDF ENSG00000184895 "Sex determining region Y" Q05066 Y 2786855-2787682 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Sexual differentiation, Transcription, Transcription regulation" "Activator, Calmodulin-binding, DNA-binding, Repressor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skin 1: 1.8;testis: 2.3" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 1.8;Muller glia cells: 2.4" "Cancer enhanced" "Detected in single" "testis cancer: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "RT4: 2.2" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 5: Muller glia cells - Visual perception" "unprognostic (1.34e-1)" "unprognostic (5.53e-4)" "unprognostic (1.61e-1)" 0.2 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.6 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.0 0.0 0.1 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.6 0.4 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.1 ST3GAL2 "SIAT4B, ST3GalA.2, ST3GALII" ENSG00000157350 "ST3 beta-galactoside alpha-2,3-sialyltransferase 2" Q16842 16 70375977-70439237 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 56.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 29.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017270 Approved Uncertain Vesicles "Intracellular and membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 72: Non-specific - Transcription" "Cluster 1: K-562 - Erythropoiesis" "Cluster 65: Plasmacytoid DCs - Unknown function" Vesicles "HPA017270: AB_1857523" "unprognostic (2.76e-2)" "unprognostic (6.33e-2)" "unprognostic (3.41e-1)" "unprognostic (1.35e-1)" "unprognostic (4.99e-1)" "unprognostic (1.01e-1)" "prognostic unfavorable (2.79e-4)" "unprognostic (1.14e-2)" "unprognostic (2.21e-1)" "unprognostic (1.91e-2)" "prognostic favorable (2.33e-4)" "unprognostic (9.54e-2)" "prognostic unfavorable (3.34e-6)" "unprognostic (7.42e-2)" "unprognostic (8.83e-3)" "unprognostic (4.64e-2)" "unprognostic (5.20e-2)" 8.6 8.3 4.7 6.4 5.8 7.4 7.2 8.4 6.5 9.3 1.6 9.2 3.5 12.5 1.1 2.6 8.2 2.5 10.5 7.1 2.9 8.2 10.3 9.0 6.3 3.1 2.6 7.2 3.6 2.6 6.4 3.2 2.6 7.1 1.6 1.7 3.2 2.8 15.8 4.2 7.1 4.1 1.9 13.2 4.7 6.7 3.3 3.6 6.0 3.1 3.4 8.4 5.6 2.9 1.7 8.6 7.7 11.2 3.9 5.4 2.3 6.1 6.0 6.2 3.0 5.5 4.0 4.6 9.8 6.3 5.8 1.9 3.2 2.5 3.3 9.9 5.0 18.0 4.5 8.7 4.7 6.7 29.4 4.1 1.5 6.7 1.3 8.2 8.6 7.6 25.1 4.2 3.7 1.5 7.5 19.8 10.1 2.9 4.5 13.9 2.9 5.9 5.1 1.5 3.7 9.4 15.8 0.6 7.1 8.1 2.4 7.3 9.9 9.0 10.0 4.0 4.7 8.6 3.9 9.7 10.0 5.9 12.5 4.2 1.9 5.2 2.0 1.8 1.7 2.0 2.3 2.0 1.0 2.9 3.8 3.0 10.1 2.8 1.3 14.3 2.6 1.1 4.7 5.8 8.4 6.5 7.1 2.9 3.1 2.6 2.6 1.9 3.3 2.9 15.4 9.6 5.2 13.4 12.6 3.3 4.2 2.1 2.2 15.7 2.8 3.0 6.8 10.0 1.9 9.2 14.6 4.7 56.1 4.5 0.0 5.7 16.9 1.7 6.5 15.0 13.2 24.8 21.3 4.4 2.5 11.0 2.6 2.2 17.7 19.7 18.2 13.1 13.7 18.5 15.2 4.5 2.0 15.4 35.1 33.2 11.8 11.9 1.8 17.8 24.9 5.6 23.7 16.6 7.4 1.8 1.5 8.2 13.5 3.0 6.8 5.7 1.3 11.1 6.6 8.5 8.8 9.3 8.9 1.1 2.4 1.8 11.5 4.7 5.6 2.3 ST6GAL1 SIAT1 ENSG00000073849 "ST6 beta-galactoside alpha-2,6-sialyltransferase 1" P15907 3 186930325-187078553 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "liver: 495.9;lymphoid tissue: 148.1" "Cell type enhanced" "Detected in many" "Collecting duct cells: 237.3;Hepatic stellate cells: 258.5;Hepatocytes: 608.7;Microglial cells: 602.4" "Cancer enhanced" "Detected in all" "liver cancer: 70.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 250.6;U-266/70: 628.0;U-266/84: 887.9;U-698: 334.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015018, CAB016122" Supported "Secreted to blood" NA NA 15000000 3300000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 85: Liver - Metabolism" "Cluster 29: U-266 - Adaptive immune response" "Cluster 15: Hepatocytes - Hemostasis" "CAB015018: AB_629203, CAB016122: AB_627178" "unprognostic (5.85e-3)" "unprognostic (4.19e-2)" "unprognostic (1.30e-1)" "unprognostic (1.62e-1)" "unprognostic (2.64e-1)" "unprognostic (2.44e-2)" "unprognostic (1.38e-3)" "unprognostic (3.43e-2)" "unprognostic (3.17e-1)" "unprognostic (2.20e-1)" "unprognostic (3.99e-1)" "unprognostic (1.43e-1)" "unprognostic (1.91e-2)" "unprognostic (7.30e-3)" "unprognostic (1.25e-1)" "unprognostic (1.16e-1)" "unprognostic (1.93e-2)" 24.5 12.5 27.0 50.2 26.2 15.2 32.5 29.8 24.8 61.4 33.3 38.1 13.9 16.1 5.9 13.5 27.0 17.8 36.0 25.8 33.9 60.0 495.9 30.1 101.7 44.0 37.5 10.1 8.1 45.5 9.8 18.5 50.3 48.8 45.4 2.6 39.3 14.6 12.8 8.3 29.1 18.9 44.1 67.5 28.8 3.5 39.2 66.6 64.8 20.2 148.1 28.0 8.9 48.3 4.3 5.0 20.6 17.1 1.1 0.0 36.3 1.6 3.0 1.4 2.0 1.9 2.0 250.6 19.5 0.1 8.8 10.1 132.7 15.4 1.6 11.3 7.4 10.1 0.8 119.0 1.3 22.8 75.0 1.7 28.3 0.0 11.5 19.9 77.5 24.2 52.2 20.3 5.2 8.7 17.0 14.7 49.9 11.3 7.6 38.2 0.4 8.1 9.9 0.5 36.4 4.1 1.5 26.6 64.6 29.1 38.9 16.8 32.6 0.2 3.3 0.6 2.1 628.0 887.9 334.0 0.5 45.4 84.7 22.6 8.9 3.6 46.9 16.2 42.9 87.9 51.3 39.7 14.2 83.3 80.4 58.4 4.2 26.9 29.3 11.9 43.8 58.7 27.0 26.2 29.8 24.8 25.8 33.9 44.0 37.5 50.3 44.1 39.2 48.3 34.6 44.8 27.4 13.4 110.0 4.0 13.8 68.0 4.6 0.3 5.1 4.1 26.2 75.8 55.9 237.3 0.0 0.3 26.3 20.7 0.0 17.1 0.5 8.9 5.0 56.0 94.1 24.8 47.2 0.9 3.5 3.7 7.7 16.1 10.8 7.3 258.5 608.7 20.3 0.0 31.5 10.9 34.6 61.3 16.4 1.1 0.3 18.2 7.2 602.4 17.2 0.1 26.8 145.3 2.8 6.0 17.8 0.7 124.3 103.6 0.6 0.5 39.8 1.1 0.0 2.2 6.8 0.0 0.5 0.8 1.6 0.7 28.4 0.3 37.3 39.0 ST6GALNAC3 SIAT7C ENSG00000184005 "ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3" Q8NDV1 1 76074746-76634603 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 21.0" "Group enriched" "Detected in many" 4 "Microglial cells: 912.5;Oligodendrocytes: 698.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "AF22: 35.8;HUVEC TERT2: 45.9;SK-MEL-30: 62.3;TIME: 20.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054566, HPA055399" Uncertain Enhanced Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA054566: AB_2682526, HPA055399: AB_2682806" "unprognostic (7.85e-2)" "unprognostic (1.78e-1)" "unprognostic (2.99e-2)" "unprognostic (2.70e-4)" "unprognostic (2.76e-2)" "unprognostic (2.21e-2)" "unprognostic (6.55e-3)" "unprognostic (7.31e-2)" "unprognostic (2.14e-1)" "unprognostic (4.57e-1)" "unprognostic (1.50e-1)" "unprognostic (5.95e-2)" "unprognostic (9.97e-4)" "unprognostic (3.33e-4)" "unprognostic (5.44e-2)" "unprognostic (1.92e-1)" "unprognostic (3.44e-4)" 8.8 1.4 5.8 1.8 13.3 3.1 6.4 14.3 8.4 1.9 10.4 2.0 0.7 5.9 0.5 1.9 2.7 2.5 4.4 6.9 9.0 8.7 2.0 5.2 2.0 15.2 10.6 2.3 0.9 4.4 2.1 3.1 17.2 1.1 2.4 3.9 1.1 1.6 1.6 0.8 1.4 4.5 13.3 1.4 1.5 0.3 11.3 0.9 13.3 6.5 0.7 2.6 1.6 21.0 0.2 0.0 35.8 0.0 0.6 0.0 0.0 0.0 4.2 0.6 0.4 11.9 0.1 0.6 2.4 0.3 2.3 0.1 0.0 0.4 0.3 0.0 2.5 0.0 0.0 0.0 0.4 0.0 0.0 0.4 0.6 0.0 0.0 1.1 45.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.4 2.9 0.0 1.8 1.7 0.0 0.0 0.0 2.7 8.8 0.0 0.0 62.3 8.3 0.0 0.2 20.6 0.3 2.8 0.1 3.3 0.0 0.0 0.0 0.0 8.4 5.5 0.0 6.3 2.8 0.0 2.2 0.0 2.6 0.3 0.5 2.3 3.8 1.3 1.4 3.9 0.3 4.3 0.0 0.0 1.9 5.8 13.3 14.3 8.4 6.9 9.0 15.2 10.6 17.2 13.3 11.3 21.0 59.8 3.2 1.5 174.3 5.6 0.3 0.2 0.0 0.6 3.2 0.6 1.0 1.2 0.0 0.0 3.7 0.0 0.1 0.2 0.5 0.0 0.0 0.0 0.1 4.5 23.2 0.0 0.4 107.0 0.0 0.1 2.5 3.6 0.1 0.0 0.8 66.0 0.8 1.1 0.0 101.4 0.5 0.0 9.8 0.7 0.8 0.0 3.7 5.4 912.5 3.0 12.3 1.0 23.1 698.3 0.2 3.4 0.0 0.2 0.1 0.0 0.0 0.0 0.5 0.0 1.1 1.3 0.2 0.7 0.1 0.4 0.1 2.0 6.9 0.3 0.1 STAM2 Hbp ENSG00000115145 "Signal transducing adaptor molecule 2" O75886 2 152116801-152175763 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 147.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 16.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035528, HPA035529" Enhanced Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 30: Epithelial cell lines - Translation" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "Nucleoplasm, Cytosol" "HPA035528: AB_10601606, HPA035529: AB_10672868" "unprognostic (1.53e-1)" "unprognostic (1.79e-1)" "unprognostic (4.81e-2)" "unprognostic (1.73e-1)" "unprognostic (2.31e-1)" "unprognostic (5.16e-2)" "unprognostic (2.76e-2)" "unprognostic (3.15e-2)" "unprognostic (6.54e-2)" "unprognostic (1.20e-1)" "unprognostic (1.22e-1)" "unprognostic (7.92e-2)" "unprognostic (1.11e-2)" "unprognostic (1.28e-1)" "unprognostic (1.76e-1)" "unprognostic (2.82e-1)" "unprognostic (1.03e-2)" 9.7 9.9 7.3 7.9 8.3 3.1 12.5 7.5 8.9 10.9 8.0 10.3 9.3 10.9 8.7 9.1 12.8 9.3 9.6 6.3 7.7 14.6 11.0 10.8 8.7 7.5 7.9 11.0 8.8 12.8 6.5 10.3 7.9 12.9 10.9 11.1 11.9 8.9 5.8 10.8 9.3 10.1 8.0 8.3 11.7 12.6 7.4 8.5 14.3 7.7 8.9 10.7 6.6 9.7 8.3 7.9 7.2 8.8 18.5 22.0 7.7 16.8 19.4 10.7 13.6 7.8 7.8 10.8 13.1 24.2 9.4 8.3 8.0 15.6 17.1 13.3 6.3 7.8 5.1 11.8 21.2 11.5 14.6 16.9 14.6 20.0 26.8 15.5 11.7 7.2 5.1 7.5 22.2 8.1 6.1 8.9 4.5 6.1 11.2 4.9 8.9 5.9 16.7 14.1 3.8 5.9 9.3 8.2 14.1 8.0 11.1 10.5 15.3 23.7 7.6 18.8 10.3 6.1 6.7 6.8 17.9 9.2 13.2 16.8 3.4 4.6 1.7 4.6 1.6 1.7 1.8 1.9 2.7 2.0 1.5 1.9 8.6 2.6 7.1 3.2 2.2 1.6 7.3 8.3 7.5 8.9 6.3 7.7 7.5 7.9 7.9 8.0 7.4 9.7 17.6 25.6 33.5 39.2 10.9 13.8 12.0 16.4 15.9 10.6 17.9 11.6 30.5 7.2 28.9 16.5 16.7 7.4 14.7 22.1 23.5 13.9 147.8 37.2 25.5 15.1 8.3 13.5 43.8 14.2 14.6 22.7 27.0 22.2 27.1 14.8 17.5 16.0 16.7 1.7 39.7 20.2 20.3 20.0 13.0 64.4 15.8 16.9 14.2 32.8 19.6 14.7 8.2 51.8 61.0 21.2 18.2 15.4 10.9 14.3 13.9 14.8 55.6 11.6 26.3 18.0 16.1 54.1 20.1 13.5 13.2 20.2 9.3 18.2 13.5 16.1 STARD10 "CGI-52, NY-CO-28, PCTP2, SDCCAG28" ENSG00000214530 "StAR related lipid transfer domain containing 10" Q9Y365 11 72754729-72794047 "Metabolic proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 709.7" "Cell type enhanced" "Detected in all" "Early spermatids: 520.2;Hepatocytes: 660.0;Intestinal goblet cells: 717.9;Late spermatids: 2055.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 21.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 617.7;OE19: 1316.9;SK-BR-3: 427.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026661 Uncertain Supported Cytosol NA NA 13000 "Cluster 52: Eosinophils - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "HPA026661: AB_1857538" "prognostic favorable (6.92e-4)" "unprognostic (2.07e-1)" "unprognostic (8.03e-2)" "unprognostic (1.74e-3)" "unprognostic (3.71e-2)" "unprognostic (1.37e-2)" "unprognostic (2.50e-2)" "unprognostic (2.16e-1)" "unprognostic (4.16e-1)" "unprognostic (4.69e-2)" "unprognostic (5.81e-2)" "unprognostic (1.67e-1)" "unprognostic (4.24e-3)" "unprognostic (8.42e-2)" "unprognostic (2.29e-1)" "unprognostic (2.12e-2)" "unprognostic (1.04e-1)" 11.8 178.2 35.1 17.7 37.6 10.3 62.1 39.2 41.8 71.9 40.9 180.6 48.5 27.3 102.9 52.0 26.4 59.5 72.5 33.9 34.1 50.1 709.7 37.7 14.5 38.0 33.0 31.0 212.6 73.2 36.2 40.2 38.2 86.2 188.1 18.7 94.5 30.9 66.7 62.6 66.0 26.7 29.9 20.2 266.9 184.3 34.4 15.6 47.9 157.9 21.8 24.5 41.1 35.7 51.2 15.3 7.7 28.7 9.8 9.6 98.3 5.6 26.2 17.3 17.3 209.8 36.7 4.4 16.7 19.2 42.3 31.8 23.4 46.8 20.2 28.3 9.0 5.9 11.1 217.6 35.2 1.6 10.0 6.6 127.0 19.1 26.7 47.2 17.8 10.0 12.1 21.5 3.9 617.7 4.8 11.1 3.4 1316.9 20.1 4.5 13.3 3.4 23.5 61.4 13.0 10.1 8.6 427.4 73.3 32.8 235.5 6.3 13.6 17.0 11.4 6.0 10.1 22.2 19.8 7.5 4.3 5.6 6.5 12.9 2.6 16.0 1.6 1.1 1.2 4.2 1.5 1.7 1.2 2.4 1.6 1.6 21.7 7.5 0.6 2.6 2.1 1.1 35.1 37.6 39.2 41.8 33.9 34.1 38.0 33.0 38.2 29.9 34.4 35.7 10.6 35.3 74.1 8.1 18.1 31.5 76.3 41.0 25.0 10.5 163.3 125.3 45.3 270.2 76.4 55.2 22.9 212.8 17.1 362.8 123.3 70.7 520.2 26.5 6.8 18.5 302.2 22.9 11.6 94.3 93.1 21.1 372.1 25.3 25.4 10.1 30.0 660.0 26.4 33.7 13.9 717.9 85.5 26.0 34.4 2055.8 26.1 12.3 16.0 5.6 7.7 64.4 7.2 8.0 11.8 93.9 398.9 25.2 13.3 150.9 73.5 58.0 34.5 16.6 6.6 11.3 19.6 101.2 22.7 30.2 55.0 352.2 15.6 7.7 440.7 132.7 STARD8 "ARHGAP38, KIAA0189" ENSG00000130052 "StAR related lipid transfer domain containing 8" Q92502 X 68647666-68725842 "Metabolic proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 27.9;Endothelial cells: 26.5;Hepatic stellate cells: 18.5;Kupffer cells: 13.7;Langerhans cells: 14.9;Macrophages: 13.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 15 "classical monocyte: 1.6;intermediate monocyte: 3.2;myeloid DC: 3.4;non-classical monocyte: 4.7" "Group enriched" "Detected in many" 18 "dendritic cells: 3.4;monocytes: 4.7" "Cell line enhanced" "Detected in many" "HEL: 16.0;K-562: 20.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA060788 Uncertain NA Yes "Cluster 14: Monocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 1: K-562 - Erythropoiesis" "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA060788: AB_2684365" "unprognostic (2.00e-1)" "unprognostic (8.98e-2)" "unprognostic (1.56e-3)" "unprognostic (4.94e-3)" "unprognostic (1.73e-1)" "unprognostic (2.61e-2)" "unprognostic (2.77e-2)" "unprognostic (1.58e-1)" "unprognostic (1.71e-1)" "unprognostic (5.09e-3)" "unprognostic (9.72e-2)" "unprognostic (9.58e-2)" "unprognostic (5.19e-3)" "unprognostic (4.89e-3)" "unprognostic (9.46e-2)" "unprognostic (4.88e-2)" "unprognostic (1.07e-2)" 13.4 4.4 8.1 6.0 6.9 3.4 10.3 6.4 6.8 6.3 5.7 4.0 1.4 7.1 4.7 3.4 8.9 5.2 12.5 6.3 6.3 14.7 6.5 20.7 4.1 13.5 7.5 3.3 5.1 2.6 8.9 8.8 8.1 9.2 1.5 0.6 2.7 8.5 6.8 2.8 4.3 6.1 8.2 11.1 4.2 0.8 8.4 1.6 10.3 6.5 1.9 6.6 4.5 6.6 0.0 1.8 2.8 1.4 0.0 0.0 2.1 3.8 7.9 2.1 1.6 0.0 0.4 0.0 9.6 1.6 0.2 0.0 0.8 0.0 3.5 0.0 0.5 16.0 1.4 0.2 0.3 0.0 0.0 1.3 0.0 5.4 0.0 6.1 9.9 0.0 20.4 0.0 5.3 0.8 0.0 9.5 1.6 0.0 0.3 0.0 10.1 5.4 9.5 0.0 0.0 0.7 0.1 0.9 0.3 5.6 1.3 2.2 7.0 9.6 4.0 3.1 3.7 0.0 0.0 0.0 7.2 6.6 5.7 0.0 1.6 0.0 0.0 3.2 0.0 0.2 0.0 0.0 3.4 0.0 0.0 0.0 0.1 0.0 4.7 0.1 0.0 1.8 8.1 6.9 6.4 6.8 6.3 6.3 13.5 7.5 8.1 8.2 8.4 6.6 27.9 0.0 6.0 0.0 0.3 2.2 0.0 0.0 0.0 0.0 0.2 0.3 8.5 0.0 1.8 0.0 0.0 0.3 0.1 0.0 1.9 0.0 0.1 1.2 1.6 26.5 0.0 2.1 0.3 0.0 0.2 3.0 0.5 1.1 7.0 0.3 18.5 6.5 3.6 0.0 0.8 0.0 0.0 13.7 14.9 0.0 0.3 13.9 0.0 9.4 2.4 0.3 0.0 0.5 0.5 0.8 0.0 0.0 0.9 0.1 0.0 2.4 2.2 0.4 0.0 2.8 3.5 0.1 0.2 0.2 1.4 0.1 0.6 0.2 0.0 0.1 STK17A DRAK1 ENSG00000164543 "Serine/threonine kinase 17a" Q9UEE5 7 43582758-43650713 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 644.6;T-cells: 273.7;Urothelial cells: 326.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018138, HPA037979" Uncertain Supported "Nuclear speckles,Plasma membrane" Yes No "Cluster 48: NK-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 22: Epithelial cell types - Mixed function" "Nuclear speckles" "Plasma membrane" "HPA018138: AB_2669784, HPA037979: AB_10795247" "unprognostic (1.81e-3)" "unprognostic (1.08e-2)" "unprognostic (2.67e-1)" "unprognostic (5.41e-2)" "unprognostic (5.11e-2)" "unprognostic (3.35e-2)" "unprognostic (1.03e-2)" "unprognostic (9.15e-3)" "unprognostic (2.07e-1)" "unprognostic (6.34e-2)" "unprognostic (1.36e-2)" "unprognostic (6.61e-2)" "unprognostic (2.99e-3)" "unprognostic (3.76e-2)" "unprognostic (3.08e-1)" "unprognostic (1.97e-3)" "unprognostic (3.66e-1)" 6.7 8.1 3.9 7.9 4.2 4.8 5.2 6.9 4.9 4.0 4.0 6.4 3.2 3.5 1.2 7.2 3.9 5.3 10.8 4.0 4.1 6.3 4.6 9.4 14.4 3.4 4.4 6.2 9.1 0.8 4.2 3.2 3.6 4.3 2.4 5.5 5.8 2.1 9.9 4.6 11.5 3.3 3.6 12.6 9.5 9.0 4.3 9.0 3.8 2.5 13.5 5.6 5.0 3.1 5.8 8.2 9.0 5.3 7.8 8.3 1.9 12.3 15.1 6.6 5.9 7.5 3.1 7.9 20.2 15.3 17.8 8.5 3.6 17.4 10.4 16.9 7.0 9.3 8.2 8.4 4.9 21.1 5.6 6.4 26.4 8.2 8.6 36.4 12.6 11.0 16.7 15.1 9.6 3.6 18.2 8.0 17.3 4.1 18.3 8.4 6.9 14.2 15.6 6.7 6.9 11.2 8.1 8.5 6.1 13.6 6.5 10.8 16.9 20.7 8.3 14.3 17.2 13.3 11.2 13.5 18.4 14.0 31.7 0.5 0.0 2.7 2.0 0.0 1.5 2.4 2.0 3.2 0.1 2.2 3.0 3.0 1.6 4.9 0.1 0.4 1.3 0.9 3.9 4.2 6.9 4.9 4.0 4.1 3.4 4.4 3.6 3.6 4.3 3.1 44.2 121.8 33.1 29.0 237.8 181.9 644.6 64.5 99.6 2.9 17.7 37.8 28.7 7.2 69.8 20.2 10.4 54.8 222.3 54.4 33.2 153.0 47.0 129.1 17.4 35.2 7.2 54.1 9.5 95.4 23.3 39.1 78.0 88.3 38.8 17.7 17.9 9.6 16.9 0.0 5.6 34.3 38.7 20.3 65.9 14.7 5.9 60.9 35.6 34.7 42.1 7.9 221.4 39.2 3.7 89.4 73.0 2.6 81.2 192.6 23.8 13.2 42.4 26.3 6.6 39.4 51.3 75.8 36.1 42.3 136.1 66.8 273.7 27.0 18.0 326.1 STK33 ENSG00000130413 "Serine/threonine kinase 33" Q9BYT3 11 8391868-8594289 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 49.3;testis: 51.8" "Cell type enhanced" "Detected in many" "Astrocytes: 213.8;Early spermatids: 98.8;Endometrial ciliated cells: 220.9;Late spermatids: 157.0;Oligodendrocyte precursor cells: 117.6;Respiratory ciliated cells: 155.3;Spermatocytes: 148.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "memory B-cell: 4.1;naive B-cell: 2.2" "Lineage enriched" "Detected in single" 5 "B-cells: 4.1" "Cell line enhanced" "Detected in many" "Daudi: 23.0;hTERT-RPE1: 22.0;Karpas-707: 21.2;SCLC-21H: 22.9;U-251 MG: 24.3;U-266/84: 21.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA015742, HPA056855" Uncertain Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "Nucleoli, Cytosol" "HPA015742: AB_1857592, HPA056855: AB_2683257" "unprognostic (2.57e-2)" "unprognostic (2.80e-1)" "unprognostic (2.23e-3)" "unprognostic (2.76e-3)" "unprognostic (3.57e-1)" "unprognostic (1.40e-1)" "unprognostic (7.28e-2)" "unprognostic (3.85e-4)" "unprognostic (1.23e-1)" "unprognostic (8.06e-2)" "unprognostic (1.33e-3)" "unprognostic (9.46e-2)" "prognostic favorable (4.89e-6)" "unprognostic (2.39e-2)" "unprognostic (1.37e-1)" "unprognostic (3.49e-2)" "unprognostic (2.90e-2)" 1.3 8.1 6.7 2.0 6.6 1.3 0.5 8.5 4.9 5.6 49.3 8.3 3.3 12.0 11.3 2.7 42.3 5.1 16.2 6.1 10.1 10.2 0.4 7.1 2.0 14.7 15.6 13.4 6.5 23.1 24.1 0.1 13.3 6.4 1.5 15.6 2.1 11.5 3.9 0.2 3.4 9.3 12.0 1.5 6.0 51.8 12.8 3.8 20.0 6.0 2.2 3.4 1.7 8.3 0.0 3.4 15.4 0.0 0.0 0.0 0.0 3.0 3.1 7.0 6.2 2.2 0.0 23.0 11.5 0.6 8.7 0.0 6.9 2.5 6.0 0.0 18.9 0.0 4.2 5.6 2.5 13.4 0.0 1.1 0.0 0.2 0.0 22.0 0.5 11.2 0.0 21.2 0.3 0.0 0.4 0.0 11.2 0.0 0.0 8.8 2.2 14.3 6.1 0.0 22.9 6.2 0.0 0.0 0.1 4.3 0.0 1.3 0.0 0.0 10.6 0.2 24.3 5.1 21.2 0.3 6.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 4.1 0.0 0.7 0.0 2.2 0.0 0.6 0.0 0.1 0.0 0.4 0.1 0.2 6.7 6.6 8.5 4.9 6.1 10.1 14.7 15.6 13.3 12.0 12.8 8.3 0.1 19.2 14.5 213.8 6.2 0.0 1.3 1.9 0.0 20.7 0.1 0.3 37.8 8.6 27.5 20.2 70.9 0.1 1.4 0.2 3.9 9.5 98.8 220.9 5.5 1.8 9.1 1.7 12.0 4.9 3.3 5.0 6.1 17.8 1.3 29.3 0.4 0.0 0.3 1.7 15.4 1.6 6.1 0.0 0.0 157.0 4.4 0.6 0.0 23.4 0.0 31.0 0.0 117.6 19.7 4.4 0.4 17.0 5.2 0.5 3.6 13.5 155.3 77.4 0.0 0.2 2.7 148.3 26.8 0.2 0.0 0.0 1.3 6.3 3.5 0.0 STK39 "DCHT, SPAK" ENSG00000198648 "Serine/threonine kinase 39" Q9UEW8 2 167954020-168247595 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 159.9;Inhibitory neurons: 142.9;Oligodendrocyte precursor cells: 153.3;Oligodendrocytes: 359.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046022, HPA061803, HPA062802" Enhanced Supported Nucleoplasm,Vesicles,Cytosol NA NA 80000 "Cluster 35: T-regs - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "Vesicles, Cytosol" "CAB046022: AB_2196960, HPA061803: AB_2684616, HPA062802: AB_2684870" "prognostic favorable (3.96e-4)" "unprognostic (2.97e-2)" "unprognostic (4.40e-2)" "unprognostic (4.22e-2)" "unprognostic (4.36e-1)" "unprognostic (6.14e-2)" "prognostic unfavorable (5.67e-5)" "unprognostic (3.04e-2)" "unprognostic (8.86e-2)" "unprognostic (9.43e-2)" "unprognostic (3.20e-2)" "unprognostic (1.38e-1)" "unprognostic (2.06e-1)" "unprognostic (9.45e-2)" "unprognostic (8.61e-3)" "unprognostic (1.14e-1)" "unprognostic (6.20e-3)" 19.4 6.7 20.1 14.0 25.8 5.1 8.4 25.3 25.1 12.0 52.9 26.3 32.0 7.3 14.5 36.3 6.4 18.1 15.8 16.0 18.6 9.0 1.9 7.6 22.2 28.8 25.8 6.6 25.6 13.7 8.2 2.3 31.9 28.7 32.4 27.8 67.9 11.5 2.7 6.3 18.6 11.7 20.8 8.6 31.8 48.5 25.6 29.1 6.9 7.6 23.5 24.8 9.5 37.0 19.1 10.9 40.9 12.9 28.1 37.5 4.0 45.0 33.8 29.6 27.8 0.2 59.9 51.1 12.2 30.5 25.5 46.6 26.7 34.4 37.1 16.2 16.4 21.2 11.8 42.9 52.3 30.5 2.1 29.1 52.8 35.1 36.5 38.5 21.2 41.3 0.5 0.0 67.0 11.4 51.6 13.0 30.3 41.0 24.3 72.1 16.0 4.8 27.9 47.6 65.7 27.0 15.7 2.6 21.8 20.3 8.0 25.9 20.2 36.6 11.1 26.5 32.2 0.1 0.0 41.5 29.7 28.5 25.1 0.0 0.3 0.0 1.1 0.2 0.6 0.2 0.9 1.6 0.5 0.5 0.2 0.8 0.0 1.0 0.1 0.1 1.8 0.2 20.1 25.8 25.3 25.1 16.0 18.6 28.8 25.8 31.9 20.8 25.6 37.0 6.1 3.2 14.0 64.6 6.4 3.8 34.4 6.5 5.7 14.8 5.5 6.5 26.2 18.6 15.2 5.5 16.7 0.1 30.0 47.7 21.5 10.9 29.4 11.9 11.6 5.6 22.8 5.7 159.9 23.1 0.1 9.2 28.1 18.9 0.0 5.8 2.9 0.4 3.5 20.2 142.9 17.3 14.2 6.7 6.7 16.2 10.2 6.7 17.8 64.6 5.5 28.9 12.3 153.3 359.4 36.0 20.1 11.3 9.5 74.8 14.5 7.9 17.5 30.0 6.6 7.7 18.2 25.4 8.1 7.5 4.4 0.3 19.4 15.8 22.4 50.6 STN1 "bA541N10.2, FLJ22559, OBFC1" ENSG00000107960 "STN1 subunit of CST complex" Q9H668 10 103877569-103918184 "Disease related genes, Human disease related genes, Predicted intracellular proteins" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 37.4;Distal tubular cells: 41.1;Ductal cells: 34.6;Exocrine glandular cells: 79.2;Pancreatic endocrine cells: 62.9;Theca cells: 52.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037924, HPA037925" Supported Nucleoplasm NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA037924: AB_10671636, HPA037925: AB_10672469" "unprognostic (1.50e-1)" "unprognostic (4.22e-2)" "unprognostic (2.18e-2)" "unprognostic (5.58e-3)" "unprognostic (6.01e-2)" "unprognostic (1.53e-2)" "unprognostic (1.59e-1)" "unprognostic (1.29e-1)" "unprognostic (5.93e-2)" "unprognostic (1.72e-1)" "unprognostic (1.12e-3)" "unprognostic (3.76e-1)" "prognostic favorable (1.12e-6)" "unprognostic (1.21e-1)" "unprognostic (1.74e-1)" "unprognostic (1.20e-1)" "unprognostic (1.83e-2)" 15.7 22.2 8.8 12.2 10.1 13.5 17.1 11.3 9.4 13.3 11.5 14.5 12.0 12.0 9.8 41.0 12.2 18.3 35.0 8.2 11.1 17.9 13.1 25.2 16.0 13.1 11.0 22.2 20.9 33.6 14.9 17.1 11.5 10.2 16.4 6.4 18.7 13.3 22.4 13.3 11.0 15.4 9.9 15.3 22.2 23.4 11.5 24.5 17.6 28.9 22.8 22.5 18.5 11.2 26.8 19.7 23.8 19.6 18.6 57.6 7.6 12.6 36.5 16.4 14.6 11.4 43.6 16.7 22.2 16.1 14.7 24.8 8.7 31.0 15.3 24.1 11.9 15.3 7.0 23.5 25.6 12.7 12.9 37.2 52.1 15.9 43.9 42.9 32.0 31.2 8.5 34.9 27.3 21.7 31.5 22.0 5.5 38.7 28.5 22.7 16.4 19.2 40.5 31.3 13.7 16.1 9.3 14.9 24.4 13.4 12.5 11.0 47.1 20.4 14.1 14.5 19.4 47.3 13.1 16.6 30.4 26.4 9.0 41.7 33.2 110.3 65.1 21.3 103.4 25.5 71.9 60.4 40.2 29.6 52.3 62.6 48.8 71.3 23.7 37.1 100.2 51.5 8.8 10.1 11.3 9.4 8.2 11.1 13.1 11.0 11.5 9.9 11.5 11.2 14.7 22.4 20.9 0.0 2.3 0.0 0.0 0.0 0.0 0.0 12.7 16.9 0.0 0.0 5.0 9.2 0.0 37.4 17.2 0.0 41.1 34.6 0.0 9.2 9.9 6.4 0.0 0.0 0.0 79.2 14.0 3.9 0.0 15.4 5.1 23.8 0.0 0.0 16.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.0 13.5 0.0 0.0 0.0 0.0 62.9 0.0 0.0 1.0 0.0 0.0 12.8 7.3 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 27.0 13.3 52.4 0.0 0.0 STRADA "LYK5, NY-BR-96, Stlk, STRAD" ENSG00000266173 "STE20 related adaptor alpha" Q7RTN6 17 63682336-63741986 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 48.0;Excitatory neurons: 49.1;Inhibitory neurons: 47.5;Oligodendrocyte precursor cells: 33.2;Oligodendrocytes: 71.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031637 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Cytosol" "HPA031637: AB_10601718" "unprognostic (1.59e-1)" "unprognostic (2.19e-1)" "unprognostic (5.59e-3)" "unprognostic (5.52e-2)" "unprognostic (8.91e-2)" "unprognostic (7.56e-5)" "unprognostic (6.79e-4)" "unprognostic (3.68e-2)" "unprognostic (1.70e-1)" "unprognostic (2.28e-1)" "prognostic favorable (5.34e-5)" "unprognostic (7.29e-2)" "prognostic unfavorable (6.08e-7)" "unprognostic (1.40e-1)" "unprognostic (1.44e-1)" "unprognostic (1.25e-1)" "prognostic favorable (6.43e-4)" 21.3 28.3 32.2 12.7 32.9 18.3 19.6 31.9 35.8 23.9 30.0 23.0 8.8 20.5 18.2 21.1 23.0 13.4 23.1 32.9 32.6 27.8 23.0 19.0 20.3 34.3 31.8 24.7 17.7 19.1 26.4 13.4 32.6 22.5 11.6 13.9 15.6 14.3 14.6 20.8 19.4 17.2 31.0 32.0 20.5 49.0 32.4 20.1 20.0 10.1 20.4 22.6 20.0 32.8 12.7 37.5 31.9 32.3 30.8 22.8 12.4 23.8 21.6 33.6 29.8 9.9 14.4 19.5 14.4 20.3 16.7 10.5 21.4 23.1 33.0 21.5 20.7 38.4 25.9 23.7 21.8 36.7 26.5 23.9 19.4 38.2 22.1 22.3 37.6 30.0 24.9 20.0 32.2 23.6 43.4 25.0 16.0 10.7 21.2 27.9 50.8 23.8 30.2 24.9 36.0 39.4 16.3 26.3 26.1 32.9 19.7 26.4 30.5 31.7 22.5 25.8 20.0 19.9 22.9 24.3 23.4 21.8 25.7 19.2 9.5 8.8 9.6 6.9 8.8 10.3 8.7 10.7 15.8 7.5 8.5 7.6 10.8 16.8 10.7 13.3 7.3 8.0 32.2 32.9 31.9 35.8 32.9 32.6 34.3 31.8 32.6 31.0 32.4 32.8 6.4 9.6 7.3 48.0 12.5 0.0 0.1 0.5 6.2 2.1 3.6 3.4 0.5 0.0 2.9 9.2 0.0 2.1 9.3 1.2 0.0 7.0 1.1 8.6 9.4 3.7 0.0 3.4 49.1 2.8 0.9 4.7 6.1 7.2 2.5 12.7 0.7 0.1 1.5 1.7 47.5 2.2 2.0 1.3 1.4 2.2 0.6 6.7 0.0 27.2 17.9 1.2 5.2 33.2 71.4 4.8 2.0 1.5 10.2 0.4 1.9 2.0 2.5 3.7 0.0 2.0 4.1 3.1 1.2 4.7 0.4 2.5 9.1 9.3 2.0 0.2 STT3B "FLJ90106, SIMP, STT3-B" ENSG00000163527 "STT3 oligosaccharyltransferase complex catalytic subunit B" Q8TCJ2 3 31532638-31637616 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 264.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036448, HPA036646" Approved Supported "Endoplasmic reticulum" NA NA 17000 "Cluster 15: NK-cells - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 25: Spermatids - Spermatogenesis" "Endoplasmic reticulum" "HPA036448: AB_2675129, HPA036646: AB_10673472" "unprognostic (2.17e-2)" "unprognostic (2.23e-1)" "prognostic favorable (7.91e-5)" "unprognostic (1.60e-1)" "unprognostic (3.11e-1)" "unprognostic (2.74e-2)" "unprognostic (2.02e-2)" "unprognostic (1.44e-1)" "unprognostic (1.04e-1)" "unprognostic (2.60e-1)" "unprognostic (3.26e-3)" "unprognostic (3.68e-2)" "unprognostic (3.86e-2)" "unprognostic (9.18e-2)" "unprognostic (1.42e-1)" "unprognostic (6.71e-3)" "unprognostic (1.02e-1)" 42.8 59.9 21.1 52.2 29.5 63.7 57.1 23.3 27.0 62.1 30.9 59.7 47.9 51.8 90.3 44.8 45.3 60.2 49.4 22.6 30.7 49.6 74.8 49.3 59.9 24.3 23.1 105.5 45.7 76.6 24.8 60.3 23.9 56.3 61.4 38.6 49.9 51.3 62.1 44.7 49.1 57.7 25.4 44.2 55.1 94.3 26.1 71.8 80.7 57.8 58.8 56.6 32.1 27.6 77.9 128.0 115.4 121.7 142.0 142.3 249.7 142.3 124.9 104.2 119.9 117.7 164.5 134.0 67.8 130.0 85.8 63.9 108.1 123.5 135.9 377.1 70.2 115.0 120.7 126.4 109.4 252.0 131.1 109.8 129.7 148.8 186.7 160.7 107.1 168.3 62.8 209.6 144.0 44.4 246.8 154.8 92.9 129.6 70.7 252.3 62.6 196.0 122.0 110.7 48.7 59.4 141.3 207.2 84.5 98.3 93.4 132.8 209.3 139.8 88.6 139.7 127.3 129.0 166.4 111.4 126.9 170.0 117.6 2.1 3.3 6.2 3.1 3.9 5.0 2.4 5.6 4.4 2.9 2.7 5.3 4.3 1.2 6.1 2.9 5.5 3.0 2.0 21.1 29.5 23.3 27.0 22.6 30.7 24.3 23.1 23.9 25.4 26.1 27.6 32.1 86.6 57.7 34.6 69.6 68.1 58.4 34.1 74.6 51.0 57.2 29.5 71.1 54.3 76.0 44.1 68.8 67.3 65.3 41.8 13.7 34.1 162.8 25.0 65.9 42.0 45.1 50.9 61.5 45.3 100.5 49.6 45.3 43.5 31.1 43.6 37.9 68.2 54.8 45.4 59.4 57.5 36.7 58.0 76.0 264.9 36.4 71.5 51.6 53.4 49.1 34.2 56.7 60.3 73.3 36.5 50.0 32.7 144.2 74.1 50.5 31.5 42.2 37.4 26.3 39.0 53.3 90.9 55.2 65.0 61.8 95.4 78.3 68.4 66.1 69.4 STX18 Ufe1 ENSG00000168818 "Syntaxin 18" Q9P2W9 4 4415742-4542346 "Predicted intracellular proteins, Predicted membrane proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 119.9" "Cell type enhanced" "Detected in all" "Endometrial ciliated cells: 191.1;Glandular and luminal cells: 249.4" "Cancer enriched" "Detected in all" 5 "endometrial cancer: 43.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003019 Approved Supported "Endoplasmic reticulum,Plasma membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 89: Fibroblasts - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 44: Endometrium - Transcription" "Endoplasmic reticulum, Plasma membrane" "HPA003019: AB_1857622" "unprognostic (2.33e-1)" "unprognostic (1.65e-1)" "prognostic favorable (2.84e-4)" "prognostic favorable (6.33e-8)" "unprognostic (4.21e-1)" "unprognostic (6.77e-2)" "unprognostic (6.17e-3)" "unprognostic (2.95e-2)" "unprognostic (7.53e-2)" "unprognostic (3.22e-3)" "unprognostic (1.21e-1)" "unprognostic (1.07e-2)" "prognostic favorable (7.03e-4)" "unprognostic (1.92e-2)" "unprognostic (1.55e-1)" "unprognostic (7.44e-2)" "prognostic favorable (4.69e-4)" 10.6 16.0 8.4 10.9 9.4 12.0 10.9 8.9 10.4 119.9 14.5 12.8 18.1 53.9 8.2 10.7 48.6 14.0 13.0 7.9 9.9 29.2 15.7 10.8 13.2 9.4 8.9 11.3 22.5 16.9 14.6 12.8 10.1 10.6 13.4 8.3 12.1 8.9 16.5 12.0 15.6 15.7 8.2 10.6 18.5 30.5 10.2 9.4 11.3 9.9 12.4 11.0 11.8 9.3 26.6 16.7 19.3 20.0 16.2 23.7 26.1 30.1 26.9 27.6 22.8 35.5 37.3 35.1 69.7 27.1 24.9 13.9 34.6 17.2 27.0 15.1 18.6 22.0 22.3 43.4 24.2 38.6 17.8 22.2 14.7 23.4 16.9 15.4 23.5 27.5 21.7 30.0 19.9 14.0 35.6 27.2 26.0 21.3 36.1 31.4 14.6 28.2 28.2 15.6 24.7 22.0 22.2 14.7 26.4 16.5 21.6 18.3 27.2 16.7 18.4 15.4 32.1 21.6 35.4 40.1 20.4 29.3 21.0 10.6 15.6 10.8 15.1 16.0 18.2 16.7 14.0 13.7 23.8 14.4 11.7 13.4 3.1 16.9 20.6 37.6 14.3 14.0 8.4 9.4 8.9 10.4 7.9 9.9 9.4 8.9 10.1 8.2 10.2 9.3 17.5 32.1 9.0 52.5 15.8 7.9 8.3 20.3 9.6 39.3 14.4 11.6 20.4 18.6 25.3 20.2 20.9 31.0 27.9 33.8 70.5 32.5 80.6 191.1 38.4 14.8 4.9 15.6 40.2 27.9 19.0 18.5 23.9 249.4 8.2 21.6 6.8 10.8 28.1 10.1 48.0 22.8 32.6 13.7 12.4 76.5 14.0 21.3 14.2 48.7 26.5 25.8 16.5 37.7 56.4 36.5 28.8 14.7 20.4 15.7 32.8 25.2 34.5 17.7 6.6 13.1 18.1 94.9 35.7 13.1 9.7 31.7 18.9 27.2 20.0 13.9 SUSD5 KIAA0527 ENSG00000173705 "Sushi domain containing 5" O60279 3 33150043-33218810 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Excitatory neurons: 15.4;Inhibitory neurons: 10.5;Oligodendrocyte precursor cells: 61.3;Sertoli cells: 32.9;Smooth muscle cells: 29.0" "Cancer enhanced" "Detected in many" "melanoma: 5.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 31.1;HUVEC TERT2: 78.5;LHCN-M2: 30.4;TIME: 31.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052788 Uncertain Uncertain "Golgi apparatus,Vesicles" NA NA 17000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "Golgi apparatus, Vesicles" "HPA052788: AB_2681948" "unprognostic (1.81e-1)" "unprognostic (1.52e-2)" "unprognostic (5.84e-3)" "unprognostic (5.52e-3)" "unprognostic (1.39e-3)" "unprognostic (4.05e-2)" "unprognostic (3.72e-1)" "unprognostic (6.28e-2)" "unprognostic (2.77e-1)" "unprognostic (2.24e-2)" "unprognostic (1.69e-1)" "unprognostic (2.15e-1)" "unprognostic (6.00e-3)" "unprognostic (1.10e-3)" "unprognostic (6.45e-2)" "unprognostic (8.46e-2)" "unprognostic (1.89e-2)" 4.6 1.4 2.9 0.9 3.0 0.1 1.9 2.2 4.6 6.3 4.4 1.7 0.8 4.6 2.2 1.3 5.2 5.5 1.5 3.1 4.4 1.5 0.5 1.7 2.3 3.4 3.4 3.8 0.6 1.0 0.8 0.2 3.4 1.3 1.2 0.6 0.7 6.3 1.6 1.9 1.9 4.8 3.8 2.5 1.8 2.1 4.7 0.1 3.2 3.3 5.3 1.5 2.4 3.5 0.0 1.1 1.2 0.7 1.7 0.2 0.1 9.6 3.4 31.1 10.5 0.1 0.0 0.0 8.8 2.5 9.5 0.1 13.7 4.5 12.9 0.3 15.3 0.0 2.0 0.0 0.2 0.1 0.1 1.3 2.4 19.9 3.9 15.2 78.5 0.0 0.0 0.1 30.4 0.0 0.0 0.1 1.8 0.0 0.1 0.0 0.0 0.0 0.1 0.0 2.0 1.0 0.1 0.1 2.5 0.7 1.8 1.9 31.3 0.0 14.4 1.2 4.7 0.0 0.7 0.0 0.3 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.9 3.0 2.2 4.6 3.1 4.4 3.4 3.4 3.4 3.8 4.7 3.5 0.1 0.0 0.0 0.3 0.0 1.0 0.1 0.0 0.0 1.9 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.4 2.2 0.5 0.0 0.0 15.4 0.0 0.1 1.4 0.0 0.9 0.0 0.2 0.4 0.0 0.0 3.3 10.5 0.0 0.0 2.1 2.0 0.3 0.0 0.1 1.8 0.0 0.0 0.5 0.0 61.3 1.6 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.7 32.9 3.6 29.0 0.1 2.6 0.1 1.0 0.0 0.2 0.1 0.0 0.1 SUV39H1 "KMT1A, SUV39H" ENSG00000101945 "Suppressor of variegation 3-9 homolog 1" O43463 X 48695554-48709016 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Differentiation, Host-virus interaction, rRNA processing, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 28.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA Yes "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "unprognostic (4.92e-2)" "prognostic favorable (8.93e-5)" "unprognostic (9.51e-2)" "unprognostic (4.18e-2)" "unprognostic (1.75e-1)" "unprognostic (1.66e-2)" "unprognostic (1.36e-2)" "unprognostic (1.94e-1)" "unprognostic (1.03e-1)" "unprognostic (3.59e-2)" "unprognostic (1.13e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (1.91e-7)" "unprognostic (2.29e-3)" "unprognostic (6.47e-3)" "unprognostic (2.01e-1)" "unprognostic (5.67e-2)" 4.0 2.2 4.7 4.2 4.4 13.7 3.5 4.9 5.1 2.9 2.0 3.4 3.1 3.2 12.5 5.0 3.3 1.7 3.6 4.3 5.1 2.6 6.6 2.7 7.5 5.2 5.6 3.8 2.9 2.3 3.0 3.3 4.8 3.0 3.2 3.3 2.6 3.0 4.9 4.4 4.2 2.6 3.9 6.0 3.6 4.9 5.0 9.7 2.6 3.8 7.0 3.4 2.4 4.3 28.7 34.3 13.3 14.0 3.4 4.0 27.0 13.5 10.2 25.8 21.0 21.0 18.7 31.4 8.0 9.9 26.1 19.8 33.0 19.3 15.4 24.2 33.8 12.3 31.8 17.4 2.0 30.7 6.6 3.6 3.7 22.8 11.6 4.2 18.6 20.2 31.9 21.6 14.2 33.1 26.8 32.0 15.7 14.0 32.8 19.3 24.5 33.1 8.6 15.7 17.4 11.4 18.3 17.4 9.8 14.8 26.0 25.5 10.0 15.8 27.0 22.1 23.3 14.6 23.9 26.4 11.8 43.6 17.7 4.9 2.8 6.8 8.5 4.0 6.2 4.6 5.5 9.1 2.2 5.4 6.8 6.6 2.0 10.6 6.5 2.6 11.0 6.5 4.7 4.4 4.9 5.1 4.3 5.1 5.2 5.6 4.8 3.9 5.0 4.3 1.2 6.4 0.0 0.3 3.5 1.8 0.9 2.0 2.8 5.3 2.2 2.5 2.5 2.8 1.3 1.8 0.0 6.5 6.6 2.1 3.9 2.9 0.2 1.3 0.9 1.7 3.0 6.9 0.7 2.9 28.3 1.9 3.1 1.0 1.3 2.9 1.8 6.7 5.2 0.0 1.0 2.6 0.0 2.9 1.6 0.2 1.2 2.4 5.4 1.0 3.0 0.9 6.2 1.0 0.8 2.3 1.7 1.5 7.1 0.6 1.6 2.4 2.6 3.8 0.0 1.8 2.5 3.7 0.8 2.5 1.1 6.2 3.6 1.7 3.2 0.6 SVOP DKFZp761H039 ENSG00000166111 "SV2 related protein" Q8N4V2 12 108907741-109021068 "Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 14.3;pituitary gland: 7.4;retina: 13.0" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 41.7;Early spermatids: 65.4;Excitatory neurons: 70.3;Inhibitory neurons: 75.8;Late spermatids: 121.5" "Group enriched" "Detected in some" 9 "glioma: 0.6;pancreatic cancer: 1.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "Karpas-707: 2.8;RPMI-8226: 3.0;SCLC-21H: 1.5;SH-SY5Y: 1.3;U-266/84: 1.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016573 Uncertain NA NA "Cluster 58: Brain - Synaptic function" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA016573: AB_2197027" "unprognostic (6.88e-2)" "unprognostic (1.10e-1)" "unprognostic (2.09e-1)" "unprognostic (6.51e-3)" "unprognostic (2.18e-2)" "unprognostic (3.79e-1)" "unprognostic (1.84e-2)" "unprognostic (1.25e-1)" "unprognostic (3.38e-2)" "unprognostic (4.29e-3)" "unprognostic (3.07e-1)" "unprognostic (4.28e-3)" "unprognostic (3.94e-2)" "unprognostic (2.26e-2)" "unprognostic (6.17e-2)" 0.0 1.5 11.2 0.1 12.4 0.1 0.0 2.2 14.3 0.0 0.0 0.3 0.5 0.0 0.1 0.0 0.0 0.0 1.0 11.3 9.5 0.1 0.2 0.0 0.0 2.9 2.1 0.0 0.7 0.0 7.4 0.0 3.7 0.0 0.1 13.0 0.0 0.0 0.1 0.0 0.3 0.0 0.4 0.0 0.7 0.5 6.4 0.0 0.0 0.1 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 1.5 1.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 11.2 12.4 2.2 14.3 11.3 9.5 2.9 2.1 3.7 0.4 6.4 6.0 0.2 12.8 9.6 2.6 0.1 0.0 0.7 0.0 0.0 19.7 0.1 0.0 1.3 0.0 5.0 1.8 41.7 1.3 0.0 0.1 0.0 0.1 65.4 0.1 0.1 1.0 16.8 0.0 70.3 0.0 0.3 0.6 0.0 0.2 2.5 0.1 1.1 0.1 0.1 11.8 75.8 0.0 0.0 0.0 0.0 121.5 0.3 1.0 0.0 1.0 0.1 2.1 0.0 4.0 2.8 0.1 0.0 0.7 0.0 0.3 0.0 0.1 0.0 21.9 0.0 1.5 0.7 0.7 0.9 0.0 0.0 0.8 0.5 0.1 0.0 0.4 SWI5 "bA395P17.9, C9orf119, SAE3" ENSG00000175854 "SWI5 homologous recombination repair protein" 9 128275379-128316123 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 142.5" "Group enriched" "Detected in all" 9 "Early spermatids: 1180.8;Late spermatids: 1131.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052032 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Cytosol" "HPA052032: AB_2681702" "unprognostic (1.27e-2)" "unprognostic (1.74e-2)" "unprognostic (3.56e-3)" "unprognostic (3.21e-2)" "unprognostic (1.42e-3)" "unprognostic (3.28e-2)" "prognostic unfavorable (6.78e-4)" "unprognostic (2.11e-1)" "unprognostic (1.19e-1)" "unprognostic (1.81e-1)" "unprognostic (4.58e-3)" "unprognostic (1.15e-1)" "prognostic favorable (9.39e-4)" "unprognostic (1.43e-1)" "unprognostic (6.73e-2)" "unprognostic (2.40e-1)" "unprognostic (7.38e-2)" 27.5 26.5 29.0 11.2 31.3 11.0 28.2 31.3 40.8 39.2 32.7 23.5 15.9 27.5 68.8 33.3 31.7 17.8 34.9 28.7 31.9 36.4 42.3 20.6 12.5 30.4 30.8 40.8 21.2 71.4 54.5 17.6 30.4 32.8 12.7 21.1 25.6 37.1 25.2 26.0 18.6 20.3 29.7 18.0 23.0 142.5 30.4 17.1 44.0 25.6 17.7 26.4 31.5 31.6 29.2 51.4 29.7 34.8 79.2 71.8 33.7 50.6 66.7 64.2 42.6 66.6 33.5 27.7 65.7 82.6 39.5 47.8 48.1 67.5 42.6 41.4 35.7 21.0 97.5 52.9 101.9 13.6 18.6 60.8 31.7 107.4 57.8 55.9 62.5 96.8 50.5 42.8 66.5 119.9 29.6 19.6 20.3 67.8 105.3 27.1 41.0 44.4 43.6 15.2 34.0 18.9 63.0 39.8 63.0 32.9 66.2 14.5 39.0 46.4 38.0 90.9 43.3 45.6 75.0 37.0 61.8 20.9 50.7 54.3 14.2 25.8 14.5 8.7 17.0 17.6 14.1 14.4 14.7 20.2 16.7 21.6 9.0 22.2 9.1 21.4 15.6 15.3 29.0 31.3 31.3 40.8 28.7 31.9 30.4 30.8 30.4 29.7 30.4 31.6 33.8 6.4 17.4 5.2 18.0 24.5 35.1 54.0 31.3 13.7 33.6 38.9 36.2 31.5 33.5 36.8 12.5 65.7 13.7 15.7 66.5 25.5 1180.8 30.7 29.1 31.3 25.6 17.2 2.9 38.5 41.1 40.7 19.9 30.7 9.5 27.9 35.7 82.4 33.2 1.7 3.3 27.5 28.5 20.8 13.0 1131.1 43.2 31.5 37.4 2.8 23.8 50.7 20.6 4.5 7.8 29.8 27.1 31.6 17.9 34.9 68.4 84.1 29.5 21.1 32.9 25.7 31.3 93.7 44.3 33.5 21.9 117.0 18.6 32.8 23.4 36.6 SWT1 "C1orf26, FLJ20121, HsSwt1" ENSG00000116668 "SWT1 RNA endoribonuclease homolog" Q5T5J6 1 185157080-185291781 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "testis: 38.3" "Cell type enhanced" "Detected in many" "Early spermatids: 150.8;Late spermatids: 52.7;Oligodendrocytes: 55.2;Spermatocytes: 54.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 14.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-266/70: 18.4;U-266/84: 15.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024214, HPA027334" Enhanced Approved Cytosol NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 78: Testis - Spermatogenesis" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "HPA024214: AB_1845642, HPA027334: AB_1845643" "unprognostic (2.67e-3)" "unprognostic (1.32e-1)" "unprognostic (3.65e-1)" "unprognostic (4.26e-2)" "unprognostic (3.17e-3)" "unprognostic (8.41e-3)" "unprognostic (5.71e-3)" "unprognostic (9.26e-3)" "unprognostic (7.37e-2)" "unprognostic (2.68e-2)" "unprognostic (1.02e-1)" "unprognostic (4.28e-1)" "prognostic favorable (5.63e-4)" "unprognostic (1.97e-1)" "unprognostic (4.19e-2)" "unprognostic (4.50e-2)" "unprognostic (4.35e-2)" 3.3 3.2 4.0 2.9 5.8 9.0 4.1 4.5 3.9 3.8 3.7 3.4 4.9 4.3 4.4 2.7 2.9 3.7 3.6 3.2 5.3 4.8 3.3 3.4 2.8 5.2 5.1 6.3 9.2 4.3 2.4 5.6 5.3 4.6 3.3 5.4 6.5 3.1 2.9 3.0 3.8 3.2 4.6 3.0 4.9 38.3 4.7 4.9 5.2 4.5 3.0 3.3 2.8 7.2 2.1 1.8 5.0 2.7 8.1 6.2 4.2 2.1 3.6 2.6 3.9 1.5 1.7 2.1 4.1 1.6 2.6 1.8 3.1 2.8 3.3 5.6 2.1 2.2 1.2 2.0 4.0 0.7 1.8 4.6 2.8 2.8 2.5 4.4 6.3 4.2 4.8 10.2 2.7 0.7 2.5 1.9 5.4 5.5 1.0 1.9 4.5 5.2 2.5 1.3 1.0 7.7 1.7 2.6 7.2 11.7 2.9 1.4 3.0 3.4 2.2 3.2 1.3 18.4 15.2 0.8 3.8 1.3 1.3 14.2 1.9 2.8 1.5 1.8 2.8 2.3 3.1 2.3 1.2 3.3 2.9 2.2 5.6 0.8 4.3 1.1 6.1 1.1 4.0 5.8 4.5 3.9 3.2 5.3 5.2 5.1 5.3 4.6 4.7 7.2 7.1 3.2 1.1 37.2 4.0 1.0 2.0 1.4 2.8 4.3 5.0 3.4 7.3 2.8 3.2 5.5 4.2 3.2 2.2 5.1 0.0 2.9 150.8 5.3 4.4 4.9 0.0 8.2 25.5 2.7 6.8 5.5 4.6 4.9 2.5 4.5 7.9 3.8 3.7 8.4 32.3 3.6 0.0 5.7 1.9 52.7 4.7 3.1 1.8 21.5 3.8 2.6 4.1 31.7 55.2 2.1 7.8 5.7 5.7 2.4 4.4 5.3 2.4 5.4 0.0 4.3 5.7 54.3 11.5 3.0 0.6 6.7 3.6 2.3 2.9 2.3 SYCE2 CESC1 ENSG00000161860 "Synaptonemal complex central element protein 2" Q6PIF2 19 12898786-12919293 "Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Meiosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 26.7" "Group enriched" "Detected in some" 4 "Spermatocytes: 214.8;Spermatogonia: 72.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "NK-cell: 2.7" "Lineage enhanced" "Detected in single" "NK-cells: 2.7" "Cell line enhanced" "Detected in many" "EFO-21: 11.6;JURKAT: 10.4;MOLT-4: 11.1;SiHa: 11.7;U-266/70: 12.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA042080, HPA062919" Enhanced Supported Nucleoplasm NA NA "Cluster 15: NK-cells - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "HPA042080: AB_10794411, HPA062919: AB_2684905" "unprognostic (3.00e-1)" "prognostic favorable (3.85e-5)" "unprognostic (9.99e-3)" "prognostic unfavorable (9.91e-4)" "unprognostic (1.75e-1)" "unprognostic (3.48e-2)" "unprognostic (2.19e-1)" "unprognostic (1.75e-1)" "unprognostic (1.78e-1)" "unprognostic (8.28e-3)" "unprognostic (1.30e-2)" "unprognostic (8.39e-4)" "unprognostic (1.79e-10)" "unprognostic (7.55e-3)" "unprognostic (9.93e-2)" "unprognostic (1.09e-1)" "unprognostic (7.87e-5)" 0.6 0.5 0.4 0.4 0.7 3.2 0.6 1.4 0.9 0.8 0.2 0.8 0.3 0.5 0.5 0.7 0.9 0.3 0.5 0.4 0.2 0.8 1.7 0.5 1.1 0.6 0.5 1.2 0.6 0.1 0.8 0.4 0.7 1.1 0.2 1.4 0.6 0.1 0.4 1.2 0.6 0.1 0.2 0.8 0.7 26.7 0.5 1.8 0.7 0.0 0.7 0.8 0.7 1.6 5.9 1.1 3.0 1.8 0.3 0.8 3.2 1.4 0.6 0.8 0.9 0.2 0.8 4.5 11.6 0.8 1.0 1.2 1.0 0.3 0.9 1.7 0.7 1.3 2.7 0.6 0.1 3.0 4.0 0.8 0.2 0.3 0.6 1.4 0.2 10.4 1.1 1.3 0.5 2.4 11.1 2.0 1.9 0.2 3.3 3.3 1.4 1.1 0.5 0.9 2.1 1.4 11.7 0.6 0.7 0.8 2.3 3.2 0.8 0.8 1.5 4.3 0.4 12.1 1.7 5.1 1.0 4.0 5.5 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 2.7 0.0 0.0 0.2 0.0 0.4 0.7 1.4 0.9 0.4 0.2 0.6 0.5 0.7 0.2 0.5 1.6 0.3 0.0 0.0 4.9 0.6 1.3 0.3 0.9 0.0 0.7 0.4 0.6 0.1 0.0 0.2 0.0 0.0 1.3 0.1 0.1 0.0 0.2 34.3 0.4 0.2 0.5 0.0 0.0 1.7 0.4 1.9 0.3 0.0 0.5 0.0 1.8 0.0 0.2 1.0 0.0 1.7 0.0 0.0 0.6 0.8 23.5 3.1 0.3 0.0 0.0 0.0 0.5 0.0 1.5 2.7 0.1 0.1 1.2 0.1 0.3 0.1 0.2 0.2 0.2 26.3 0.4 0.4 214.8 72.2 0.0 0.4 0.3 0.2 0.1 0.3 0.2 SYCP2 SCP2 ENSG00000196074 "Synaptonemal complex protein 2" Q9BX26 20 59863564-59933655 "Disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Meiosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 43.2" "Cell type enriched" "Detected in many" 5 "Spermatocytes: 468.5" "Group enriched" "Detected in many" 6 "breast cancer: 6.7;cervical cancer: 11.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 25.9;JURKAT: 47.2;MOLT-4: 54.4;SiHa: 92.2;T-47d: 82.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA062401, HPA065613" Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 78: Testis - Spermatogenesis" "Cluster 6: T47d - Mammary gland" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "Plasma membrane, Cytosol" "HPA062401: AB_2684752, HPA065613: AB_2685519" "unprognostic (8.10e-3)" "unprognostic (8.28e-3)" "unprognostic (1.62e-1)" "unprognostic (2.48e-2)" "unprognostic (1.57e-1)" "unprognostic (1.19e-3)" "unprognostic (2.50e-2)" "unprognostic (2.18e-1)" "unprognostic (4.11e-2)" "unprognostic (1.44e-1)" "unprognostic (3.74e-1)" "unprognostic (7.02e-3)" "unprognostic (4.84e-3)" "unprognostic (8.48e-2)" "unprognostic (2.46e-1)" "unprognostic (7.87e-3)" "unprognostic (1.21e-1)" 3.2 0.8 2.2 1.4 2.8 2.4 13.9 9.7 4.9 2.4 0.0 1.3 1.6 1.6 1.2 0.9 1.3 2.4 2.5 2.2 1.1 4.3 1.1 2.2 2.6 1.8 1.8 0.7 6.6 0.7 1.9 3.9 2.2 3.8 1.1 1.5 4.4 1.0 1.3 2.7 2.4 0.7 1.4 3.1 6.1 43.2 2.5 1.3 2.4 1.0 1.7 1.8 1.5 4.1 0.3 1.3 0.2 1.4 0.6 0.8 1.4 4.1 1.1 1.8 0.2 25.9 2.6 0.1 4.0 1.8 0.8 0.6 0.5 0.1 1.0 8.5 0.6 0.2 6.1 0.4 0.2 0.4 19.0 0.4 0.4 0.4 0.0 0.9 0.0 47.2 0.2 0.0 0.9 12.5 54.4 2.9 0.4 1.5 0.3 0.0 0.1 0.2 2.1 6.1 0.2 4.5 92.2 13.3 3.3 1.6 82.6 4.7 0.5 0.1 2.8 11.2 0.0 0.0 0.0 0.0 0.0 1.7 5.2 0.7 0.1 0.7 0.8 0.0 0.8 0.2 0.4 0.5 0.0 0.2 0.2 0.4 0.7 0.0 0.0 0.0 0.3 0.2 2.2 2.8 9.7 4.9 2.2 1.1 1.8 1.8 2.2 1.4 2.5 4.1 11.5 0.0 1.1 24.5 1.4 1.0 1.1 1.0 0.0 1.9 12.7 9.4 3.6 2.8 6.3 1.8 2.1 0.8 3.0 0.1 1.9 0.9 82.3 0.4 5.0 6.5 0.0 0.0 27.5 3.6 0.4 2.1 2.6 0.5 2.5 1.2 2.9 0.0 0.5 0.0 14.6 0.1 0.0 1.2 0.8 21.8 4.7 1.6 5.4 13.1 1.4 2.3 5.2 28.6 11.1 1.2 1.2 1.9 0.4 1.8 0.3 5.4 8.6 1.1 52.6 1.7 3.8 468.5 92.4 0.6 0.0 0.4 4.1 0.2 0.3 1.2 SYN1 MRX50 ENSG00000008056 "Synapsin I" P17600 X 47571901-47619857 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding Epilepsy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 271.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 27.1;Excitatory neurons: 37.3;Horizontal cells: 28.6;Inhibitory neurons: 34.1" "Cancer enriched" "Detected in many" 4 "glioma: 11.2" "Group enriched" "Detected in many" 5 "amygdala: 81.4;basal ganglia: 127.5;cerebral cortex: 271.3;hippocampal formation: 118.3;white matter: 150.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 9.0;HHSteC: 8.1;NTERA-2: 17.4;SCLC-21H: 30.2;SH-SY5Y: 7.9;SuSa: 7.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000397, CAB021929" Enhanced NA NA 48000 "Cluster 10: Brain - Neuronal signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 41: Macrophages - Immune response" "CAB021929: , HPA000397: AB_1080146" "unprognostic (1.22e-1)" "unprognostic (9.25e-2)" "unprognostic (2.16e-3)" "unprognostic (4.48e-3)" "unprognostic (3.05e-3)" "unprognostic (7.57e-2)" "unprognostic (1.63e-1)" "unprognostic (4.31e-1)" "unprognostic (3.49e-2)" "unprognostic (6.68e-2)" "unprognostic (3.97e-3)" "unprognostic (1.32e-1)" "unprognostic (2.64e-4)" "unprognostic (2.73e-3)" "unprognostic (5.79e-2)" "unprognostic (2.95e-3)" "unprognostic (5.27e-2)" 3.9 11.0 81.4 3.5 127.5 2.0 0.9 9.0 271.3 1.2 0.0 3.7 0.6 1.3 1.4 0.7 1.9 2.6 15.3 118.3 30.7 2.2 3.0 2.9 0.4 28.5 2.3 2.9 2.2 0.7 35.7 4.4 12.7 2.3 1.8 44.0 1.2 1.7 1.9 1.3 1.8 1.7 0.0 1.1 1.9 2.6 9.9 0.9 0.5 3.8 0.7 4.1 1.6 150.4 0.0 0.0 5.0 0.7 0.2 1.0 0.0 0.9 0.2 1.4 0.4 0.0 0.0 0.0 1.6 0.1 1.6 9.0 0.5 0.0 0.4 0.6 0.1 0.5 0.0 0.0 8.1 0.0 2.1 1.9 0.0 1.5 0.3 0.0 0.1 0.7 0.6 0.3 0.2 0.2 0.3 0.3 17.4 0.0 0.1 0.1 0.1 0.3 0.0 0.0 30.2 7.9 0.0 0.1 0.1 7.2 2.2 0.0 0.2 0.0 0.9 0.1 0.1 0.2 0.1 0.0 0.7 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 81.4 127.5 9.0 271.3 118.3 30.7 28.5 2.3 12.7 0.0 9.9 150.4 0.2 0.0 0.0 5.5 0.0 0.9 0.6 0.6 0.6 27.1 0.2 0.1 3.7 1.5 0.1 0.0 10.4 0.1 0.0 0.4 0.0 0.1 0.2 0.0 0.6 0.4 4.2 0.8 37.3 0.7 0.0 2.7 1.1 0.1 0.0 1.6 3.3 1.5 0.2 28.6 34.1 0.3 2.0 1.6 3.4 1.0 2.8 5.1 0.0 7.5 4.7 6.4 0.0 10.6 5.1 0.6 0.2 3.4 0.0 1.2 0.0 0.1 0.1 7.3 6.6 0.8 2.1 3.6 2.1 0.0 0.6 0.0 0.1 3.2 0.5 0.3 SYNJ2 INPP5H ENSG00000078269 "Synaptojanin 2" O15056 6 157981863-158099176 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "brain: 116.2" "Cell type enhanced" "Detected in many" "Excitatory neurons: 102.1;Glandular and luminal cells: 114.2;Oligodendrocytes: 502.1;Pancreatic endocrine cells: 140.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "GAMG: 133.4;TIME: 109.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031575 Approved Approved Microtubules,Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 70: Brain - Nervous system development" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Microtubules Cytosol "HPA031575: AB_10604101" "prognostic unfavorable (2.63e-4)" "unprognostic (1.94e-2)" "unprognostic (7.61e-2)" "unprognostic (1.25e-2)" "unprognostic (1.48e-2)" "unprognostic (7.68e-2)" "unprognostic (1.24e-1)" "unprognostic (7.06e-2)" "unprognostic (2.91e-1)" "unprognostic (7.29e-3)" "unprognostic (1.26e-1)" "unprognostic (1.36e-1)" "prognostic unfavorable (4.02e-6)" "unprognostic (1.66e-2)" "unprognostic (3.75e-2)" "unprognostic (1.75e-1)" "unprognostic (9.45e-2)" 4.2 5.8 26.1 6.2 69.9 20.0 8.0 58.6 42.0 4.5 1.9 10.6 7.1 7.6 10.5 7.7 5.5 9.4 10.7 22.5 32.4 8.4 4.9 4.5 5.9 98.1 74.7 3.6 8.1 1.5 4.1 3.5 78.9 6.9 10.4 2.3 16.5 5.8 7.2 4.3 6.8 7.7 57.8 4.2 8.5 9.4 58.2 6.5 5.2 9.5 6.5 11.0 4.6 116.2 16.4 56.6 4.5 7.3 3.4 11.2 24.2 29.8 60.4 35.0 41.1 28.7 13.5 0.5 19.8 57.9 133.4 15.4 10.1 18.5 40.1 22.9 9.3 31.8 29.8 30.9 6.5 10.9 32.6 5.9 9.9 53.3 12.4 47.1 61.7 16.4 24.7 6.5 16.1 7.6 14.0 12.2 5.1 51.4 31.2 6.0 19.1 13.4 11.8 18.8 34.8 2.0 22.7 14.2 5.9 17.2 10.9 7.1 109.7 25.8 26.8 61.4 36.5 2.5 7.8 0.4 49.2 17.5 18.4 3.0 0.6 0.5 0.9 0.3 1.9 1.0 1.3 0.8 0.6 2.0 1.1 0.8 4.3 1.0 0.4 0.5 1.2 0.5 26.1 69.9 58.6 42.0 22.5 32.4 98.1 74.7 78.9 57.8 58.2 116.2 17.2 3.2 3.3 5.2 15.4 21.7 19.9 7.5 14.2 2.4 25.4 18.4 13.9 21.5 8.6 18.4 0.0 7.7 12.8 20.0 3.9 59.0 35.5 48.5 13.7 26.4 17.4 5.5 102.1 35.2 5.0 16.6 34.1 114.2 5.1 37.7 7.9 5.2 2.0 0.0 10.1 14.8 10.2 2.2 17.6 56.5 1.2 12.5 10.6 7.5 6.9 1.6 16.5 8.5 502.1 140.2 7.1 6.4 13.5 50.6 13.1 1.7 14.4 0.6 0.0 7.3 18.9 0.9 1.1 11.5 17.2 15.9 17.1 2.2 15.7 36.2 SYT5 ENSG00000129990 "Synaptotagmin 5" O00445 19 55171196-55180289 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 72.6;pituitary gland: 59.3" "Cell type enhanced" "Detected in some" "Early spermatids: 15.4;Enteroendocrine cells: 57.6;Excitatory neurons: 20.3;Late spermatids: 41.4" "Cancer enhanced" "Detected in many" "pancreatic cancer: 3.2" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "basophil: 1.4" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "EFO-21: 27.1;HMC-1: 60.2;K-562: 22.7;OE19: 95.7;SCLC-21H: 15.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078390 Enhanced NA NA "Cluster 17: Basophils - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 21: OE19 - Mitochondria" "Cluster 25: Spermatids - Spermatogenesis" "HPA078390: AB_2732382" "unprognostic (1.18e-1)" "unprognostic (1.44e-1)" "unprognostic (9.76e-2)" "unprognostic (4.59e-2)" "prognostic unfavorable (6.54e-4)" "unprognostic (9.85e-2)" "unprognostic (3.24e-3)" "unprognostic (5.94e-2)" "unprognostic (1.36e-3)" "unprognostic (1.82e-1)" "prognostic favorable (5.54e-4)" "unprognostic (1.15e-3)" "unprognostic (3.71e-7)" "unprognostic (7.09e-2)" "unprognostic (5.21e-2)" "unprognostic (4.42e-2)" "unprognostic (3.55e-1)" 0.2 9.7 40.1 1.9 46.0 0.5 0.1 0.0 72.6 0.8 0.0 2.0 1.3 0.1 0.0 0.2 0.2 0.2 0.2 53.4 58.5 0.1 0.1 0.2 0.2 12.2 20.3 0.0 2.5 0.7 59.3 0.0 22.1 0.1 0.7 4.4 0.0 0.0 0.1 0.8 1.1 0.5 13.3 0.1 1.9 5.4 32.4 0.2 0.1 0.0 0.3 0.1 0.3 39.9 0.2 0.2 0.4 0.4 0.9 0.0 0.3 0.6 0.0 0.0 0.9 0.0 1.1 1.7 27.1 0.0 0.8 0.7 0.0 0.0 0.0 0.3 0.1 0.3 0.2 0.1 1.1 0.1 60.2 0.7 0.2 0.0 0.1 0.0 0.5 0.5 22.7 3.8 0.0 0.6 0.5 0.0 0.1 95.7 3.8 0.1 0.4 0.3 0.0 0.1 15.9 7.1 0.0 1.1 0.9 0.0 0.5 0.1 0.1 1.4 1.3 1.7 0.1 0.2 1.4 0.9 0.5 0.1 0.3 1.4 0.2 0.3 0.1 0.1 0.1 0.2 0.0 0.1 0.5 0.2 0.1 0.1 0.9 0.3 0.1 0.2 0.1 0.1 40.1 46.0 0.0 72.6 53.4 58.5 12.2 20.3 22.1 13.3 32.4 39.9 0.2 0.0 0.0 3.3 1.0 0.6 0.1 1.4 0.0 2.8 0.1 0.6 1.1 0.0 0.4 0.0 4.2 0.0 1.0 0.8 0.0 0.3 15.4 9.1 0.3 0.1 57.6 2.7 20.3 0.4 0.1 0.3 5.6 0.2 0.0 0.7 0.4 0.0 0.2 6.7 11.9 0.8 4.1 0.6 0.0 41.4 0.3 0.1 0.0 3.7 0.1 0.4 0.0 1.5 2.5 0.9 0.1 0.4 0.1 0.1 2.1 0.0 4.0 0.4 0.0 0.0 0.7 8.2 7.6 0.0 0.1 0.0 1.0 0.2 0.6 0.4 SYT9 ENSG00000170743 "Synaptotagmin 9" Q86SS6 11 7238778-7469043 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 15.9;retina: 7.6" "Cell type enhanced" "Detected in some" "Astrocytes: 48.6;Late spermatids: 23.5;Oligodendrocyte precursor cells: 55.3;Oligodendrocytes: 139.2" "Cancer enhanced" "Detected in some" "breast cancer: 2.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HEK 293: 10.3;RT4: 17.9;SH-SY5Y: 13.2;TIME: 20.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 77: Retina - Visual perception" "Cluster 15: RT4 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "unprognostic (1.47e-1)" "unprognostic (9.41e-2)" "unprognostic (1.39e-5)" "unprognostic (1.63e-1)" "unprognostic (1.12e-1)" "unprognostic (5.50e-2)" "unprognostic (4.62e-2)" "unprognostic (1.19e-1)" "unprognostic (1.69e-1)" "unprognostic (1.67e-2)" "unprognostic (1.64e-2)" "unprognostic (1.81e-1)" "unprognostic (3.31e-3)" "unprognostic (4.35e-2)" "unprognostic (1.92e-4)" "unprognostic (1.22e-4)" 0.0 2.0 9.1 0.0 9.2 0.0 0.8 11.7 5.9 0.4 1.4 0.1 0.0 1.2 0.0 0.0 0.1 0.1 0.3 4.7 7.6 2.0 3.6 0.0 0.0 9.9 11.8 0.1 1.3 0.9 1.5 0.0 9.6 1.0 0.0 7.6 0.0 3.6 0.0 0.1 0.1 0.1 8.1 0.0 0.1 0.9 15.9 0.0 1.1 0.0 0.0 0.2 0.3 11.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 3.5 0.0 0.0 0.0 0.0 17.9 3.2 13.2 0.0 0.0 0.0 0.4 0.0 0.0 20.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 9.2 11.7 5.9 4.7 7.6 9.9 11.8 9.6 8.1 15.9 11.7 0.0 0.0 0.0 48.6 0.5 0.0 0.1 0.0 0.0 13.6 0.7 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 13.9 0.0 0.2 0.0 0.0 0.0 15.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 6.2 0.0 3.3 9.8 0.0 0.0 0.3 0.0 23.5 0.0 0.0 0.0 5.6 0.0 2.0 0.0 55.3 139.2 0.0 0.0 0.0 0.0 0.2 0.0 1.5 0.0 3.5 0.0 0.0 0.1 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SYTL5 ENSG00000147041 "Synaptotagmin like 5" Q8TDW5 X 38006553-38128819 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 13.6;stomach 1: 12.1" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 37.2;Inhibitory neurons: 92.0;Intestinal goblet cells: 20.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 6.2;MCF7: 5.8;OE19: 8.4;SK-MEL-30: 14.8;SuSa: 19.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA026074 Uncertain Approved Nucleoplasm,Microtubules,Cytosol NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Microtubules, Cytosol" "HPA026074: AB_1857697" "unprognostic (3.60e-2)" "unprognostic (1.71e-1)" "unprognostic (2.35e-1)" "unprognostic (6.68e-2)" "unprognostic (3.09e-3)" "unprognostic (3.22e-2)" "unprognostic (2.01e-2)" "unprognostic (1.94e-1)" "unprognostic (1.72e-1)" "unprognostic (3.35e-1)" "unprognostic (1.10e-1)" "unprognostic (6.72e-2)" "unprognostic (1.30e-2)" "unprognostic (5.21e-2)" "unprognostic (1.51e-1)" "unprognostic (1.47e-2)" "unprognostic (2.96e-2)" 0.0 8.2 6.5 0.3 7.2 0.0 2.5 0.0 5.6 5.6 0.1 2.8 2.2 2.2 0.8 3.1 0.4 0.5 1.1 6.7 10.7 1.2 4.4 0.6 0.0 3.4 13.6 0.1 5.8 0.0 0.6 7.4 6.3 0.9 3.2 0.5 2.2 0.4 0.0 0.1 2.4 3.3 2.5 0.0 12.1 0.6 8.6 0.0 0.1 0.0 0.0 0.9 0.8 0.9 0.0 1.2 0.2 0.0 0.1 0.0 1.3 0.0 0.0 0.0 0.0 6.2 1.4 0.0 0.0 0.5 2.2 0.7 0.0 0.0 0.0 0.0 0.6 0.0 3.0 0.0 0.0 0.0 0.0 0.1 0.4 0.6 0.0 0.7 0.1 0.0 0.1 0.2 0.2 5.8 0.0 0.0 2.5 8.4 0.0 0.0 2.0 0.0 0.0 0.4 3.2 0.0 0.3 1.2 14.8 19.5 0.0 0.0 0.0 0.1 4.7 0.0 3.3 0.1 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 6.5 7.2 0.0 5.6 6.7 10.7 3.4 13.6 6.3 2.5 8.6 0.9 0.0 0.0 2.0 1.6 0.0 0.0 0.2 0.8 0.0 0.0 4.0 1.5 0.3 0.0 8.7 0.0 0.0 3.3 0.0 4.6 0.0 0.0 0.0 0.7 3.6 0.1 3.0 0.0 1.4 0.9 3.6 0.6 37.2 4.0 0.0 1.0 0.4 1.3 0.3 0.0 92.0 20.8 6.1 0.0 0.0 0.0 0.6 0.2 0.0 1.0 0.2 0.0 0.0 0.0 1.1 4.9 3.0 2.6 0.3 0.6 0.6 0.1 3.3 0.0 0.0 0.0 0.7 0.0 0.0 1.0 0.0 8.9 0.1 0.0 0.7 1.0 TAB3 MAP3K7IP3 ENSG00000157625 "TGF-beta activated kinase 1 (MAP3K7) binding protein 3" Q8N5C8 X 30827442-30975084 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034980, HPA034981" Approved Approved "Nuclear speckles,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 40: Granulosa cells - Unknown function" "Nuclear speckles, Cytosol" "HPA034980: AB_10602708, HPA034981: AB_2674394" "unprognostic (4.39e-1)" "unprognostic (2.22e-1)" "unprognostic (3.04e-2)" "unprognostic (1.73e-1)" "unprognostic (6.35e-2)" "unprognostic (2.95e-3)" "unprognostic (1.49e-2)" "unprognostic (1.73e-2)" "unprognostic (3.10e-1)" "unprognostic (2.14e-1)" "unprognostic (1.65e-1)" "unprognostic (3.51e-1)" "prognostic favorable (8.45e-4)" "unprognostic (5.91e-2)" "unprognostic (1.25e-1)" "unprognostic (9.12e-2)" "unprognostic (2.75e-1)" 8.1 7.6 3.6 8.0 4.5 16.8 8.9 3.9 6.7 8.5 20.6 9.6 7.7 18.0 8.9 16.6 9.7 8.1 8.6 5.3 4.0 14.3 27.1 9.0 8.9 5.2 6.5 12.2 24.9 31.8 6.5 11.6 4.7 14.6 9.5 23.9 9.7 12.6 10.7 9.7 7.9 13.3 3.1 8.5 12.5 15.3 4.4 9.7 10.0 8.9 12.6 7.2 8.3 5.7 40.2 9.5 9.6 9.8 7.3 11.0 10.1 12.2 15.3 8.0 9.1 10.8 33.5 18.1 7.3 14.2 15.5 20.4 14.8 31.0 11.6 31.2 14.2 16.9 10.9 26.4 6.3 18.0 12.7 8.0 18.2 13.8 35.0 13.9 13.5 13.5 19.7 14.4 10.6 19.4 14.4 9.1 11.5 7.2 15.9 9.1 16.8 13.5 13.3 11.6 8.0 11.3 13.6 20.3 26.0 17.8 17.5 7.1 13.0 8.9 13.0 44.8 11.3 18.6 15.3 17.8 13.9 8.3 12.7 0.0 0.1 0.2 0.1 0.2 0.2 0.2 0.2 0.1 0.1 0.3 0.2 0.2 0.1 0.9 0.2 0.0 0.1 0.1 3.6 4.5 3.9 6.7 5.3 4.0 5.2 6.5 4.7 3.1 4.4 5.7 9.6 12.8 13.2 14.0 10.2 9.1 7.9 7.2 6.8 7.4 10.0 5.3 11.4 20.0 10.5 11.0 12.5 15.1 11.0 12.3 3.9 8.4 1.5 13.0 23.0 8.8 7.2 39.2 23.2 6.9 4.9 5.6 12.8 11.9 14.5 28.6 10.0 26.0 7.7 11.8 22.3 10.8 6.1 16.0 13.7 3.4 10.8 12.6 5.4 20.6 11.5 6.7 3.1 21.6 21.2 9.9 11.2 16.1 7.3 12.6 7.3 11.2 19.6 20.4 0.0 6.3 6.7 3.3 2.2 9.6 10.1 22.4 10.9 24.4 9.8 13.2 TACC3 "ERIC-1, ERIC1, maskin, Tacc4" ENSG00000013810 "Transforming acidic coiled-coil containing protein 3" Q9Y6A5 4 1712891-1745171 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 58.9;lymphoid tissue: 52.4;testis: 50.6" "Cell type enhanced" "Detected in many" "Early spermatids: 70.4;Hofbauer cells: 43.9;Late spermatids: 69.9;Spermatocytes: 94.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005781, HPA006050, CAB010111, HPA022039" Enhanced Enhanced "Vesicles,Mitotic spindle,Centriolar satellite,Cytosol" Yes Yes 11000 "Cluster 5: Granulocytes - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Mitotic spindle, Centriolar satellite, Cytosol" Vesicles "CAB010111: AB_628323, HPA005781: AB_1857724, HPA006050: AB_2667505, HPA022039: AB_1857725" "unprognostic (2.95e-1)" "unprognostic (1.18e-1)" "unprognostic (7.71e-2)" "unprognostic (4.35e-2)" "unprognostic (6.58e-2)" "unprognostic (1.84e-2)" "prognostic unfavorable (3.30e-4)" "unprognostic (1.10e-3)" "unprognostic (4.61e-2)" "unprognostic (9.12e-2)" "unprognostic (2.91e-2)" "unprognostic (2.26e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (4.66e-2)" "unprognostic (2.09e-1)" "unprognostic (4.44e-3)" "unprognostic (9.75e-2)" 5.3 3.9 4.2 24.9 4.3 58.9 3.5 5.2 5.3 3.6 5.2 10.3 6.6 3.3 4.8 14.9 2.8 4.2 3.3 4.5 4.4 2.7 3.5 6.5 43.2 4.8 5.3 2.2 1.4 2.3 2.6 8.7 4.8 2.4 10.6 1.9 3.9 2.5 2.0 6.4 12.9 6.4 4.2 22.1 6.4 50.6 5.1 52.4 2.8 3.4 39.3 5.0 5.4 4.7 106.7 88.7 129.5 72.2 6.7 15.2 72.9 114.6 62.1 135.4 87.6 93.5 122.8 133.8 48.0 65.4 149.9 71.4 142.5 86.8 131.1 59.8 77.0 113.8 67.2 85.8 5.9 146.6 85.5 5.2 5.7 85.6 46.0 26.0 102.2 110.3 106.3 90.8 123.8 87.1 207.5 204.0 139.3 89.2 111.6 139.1 90.5 55.0 73.8 125.5 99.8 62.8 70.1 42.3 33.1 95.2 83.3 90.5 56.4 75.4 90.0 65.4 176.7 69.5 102.5 207.1 43.2 141.1 109.1 45.5 30.0 37.9 8.5 12.5 11.1 7.8 16.5 11.5 15.3 10.8 28.3 13.1 91.8 12.2 9.6 8.3 42.5 32.5 4.2 4.3 5.2 5.3 4.5 4.4 4.8 5.3 4.8 4.2 5.1 4.7 6.0 0.0 6.7 2.0 16.5 2.2 1.2 3.2 1.2 1.7 2.4 3.0 2.6 2.8 3.4 9.2 8.4 19.5 6.4 11.2 0.0 2.2 70.4 4.2 2.8 5.2 1.2 37.2 2.3 0.7 20.4 6.0 12.8 4.3 5.1 24.5 8.9 5.1 43.9 5.0 3.2 9.5 4.1 23.2 10.8 69.9 2.8 34.1 0.0 4.7 24.4 1.4 6.2 0.5 0.8 2.9 4.2 2.6 18.0 1.3 2.6 2.8 0.9 2.7 6.6 2.0 4.8 94.3 37.7 12.8 1.4 4.0 23.2 2.2 16.1 2.7 TAF10 "TAF2A, TAF2H, TAFII30" ENSG00000166337 "TATA-box binding protein associated factor 10" Q12962 11 6606294-6612539 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 361.8;Late spermatids: 1039.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004148, CAB022405" Supported Supported Nucleoplasm NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 43: Testis - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "CAB022405: , HPA004148: AB_1857736" "unprognostic (1.69e-3)" "unprognostic (2.32e-1)" "unprognostic (3.19e-2)" "unprognostic (6.21e-3)" "unprognostic (9.10e-2)" "unprognostic (6.99e-2)" "unprognostic (5.24e-3)" "unprognostic (9.03e-3)" "unprognostic (1.12e-1)" "unprognostic (1.24e-2)" "unprognostic (3.46e-1)" "unprognostic (1.10e-1)" "prognostic unfavorable (1.84e-5)" "unprognostic (1.38e-1)" "unprognostic (2.55e-1)" "unprognostic (9.64e-3)" "unprognostic (3.80e-3)" 78.9 140.7 147.5 53.3 150.3 93.0 69.2 149.2 204.1 59.3 142.6 66.2 44.3 63.6 97.5 103.1 61.7 28.3 130.0 147.7 156.2 100.9 151.6 76.7 56.8 157.1 153.2 50.0 152.8 53.2 96.2 31.0 155.9 79.8 54.1 30.8 69.6 42.9 107.5 61.2 68.1 38.7 147.7 125.4 100.1 190.7 149.9 82.0 74.6 50.0 76.3 72.1 58.3 150.9 82.4 138.2 88.7 77.7 140.6 135.1 67.5 61.4 134.6 98.9 98.6 102.0 145.0 45.4 77.2 111.4 137.4 68.6 66.0 99.7 97.3 92.2 95.3 64.2 95.6 122.2 227.7 85.4 98.9 157.8 125.1 77.5 163.0 168.0 110.6 139.5 67.0 80.7 157.4 159.5 122.2 78.5 62.6 130.9 107.6 72.2 46.8 78.5 163.5 108.1 62.2 84.4 82.9 95.0 107.6 129.8 67.1 100.6 64.6 67.2 78.9 97.6 87.9 94.6 70.7 73.4 110.4 44.5 108.2 12.7 9.9 11.8 9.7 15.7 8.8 9.8 9.4 11.1 10.8 11.6 8.8 7.8 27.9 8.7 16.2 23.7 11.4 5.1 147.5 150.3 149.2 204.1 147.7 156.2 157.1 153.2 155.9 147.7 149.9 150.9 106.4 3.2 23.3 6.2 60.1 21.4 56.8 9.4 32.5 23.0 116.3 148.0 51.5 47.1 13.1 36.8 20.9 48.5 130.7 79.7 19.6 18.2 361.8 93.8 90.0 39.3 34.7 45.4 4.4 33.3 55.2 43.0 56.6 86.3 5.1 70.5 26.7 53.8 65.9 23.5 4.4 50.8 2.0 78.4 44.4 1039.1 24.5 91.2 26.6 9.4 36.3 84.7 53.5 2.5 9.9 30.7 68.5 19.2 89.6 85.8 55.5 43.1 14.0 27.1 0.0 36.3 50.0 108.8 33.2 75.0 29.1 53.6 65.0 124.1 44.2 88.7 TAF3 "TAF140, TAFII140" ENSG00000165632 "TATA-box binding protein associated factor 3" Q5VWG9 10 7818505-8016631 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066184 Supported "Nucleoplasm,Nuclear membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 21: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm "Nuclear membrane" "HPA066184: AB_2685631" "unprognostic (3.82e-2)" "unprognostic (2.87e-3)" "unprognostic (6.60e-2)" "unprognostic (4.23e-1)" "unprognostic (6.88e-2)" "unprognostic (2.38e-1)" "prognostic unfavorable (2.14e-7)" "unprognostic (2.97e-1)" "unprognostic (1.45e-1)" "unprognostic (2.71e-2)" "unprognostic (9.71e-2)" "unprognostic (6.30e-3)" "prognostic unfavorable (5.01e-4)" "unprognostic (8.59e-2)" "unprognostic (3.44e-1)" "unprognostic (9.44e-2)" "unprognostic (1.74e-1)" 5.4 4.9 7.1 4.8 7.9 6.9 4.5 9.9 9.0 4.7 4.8 5.1 2.8 5.2 2.2 3.0 4.3 3.3 5.9 6.1 7.6 4.0 3.7 3.9 6.1 7.9 9.0 7.0 4.3 5.2 3.1 4.5 7.9 3.5 3.5 5.3 3.6 4.4 10.7 5.2 3.8 4.2 7.2 5.5 3.7 7.5 8.2 7.0 4.3 7.6 4.6 5.0 4.2 7.2 7.9 7.2 8.0 4.3 9.0 6.2 11.1 9.2 3.5 6.8 7.7 15.6 5.8 13.4 6.9 5.4 2.8 8.4 8.9 7.9 8.5 10.9 9.8 11.5 5.0 10.0 7.7 7.8 10.1 4.2 7.8 9.5 4.6 4.3 6.5 14.5 13.0 13.5 7.8 14.9 17.7 5.5 6.1 11.5 4.2 14.2 7.6 9.0 3.9 4.9 4.3 6.1 10.0 7.2 9.4 7.8 13.1 8.1 8.1 6.1 10.7 16.3 9.1 8.0 10.3 14.4 5.9 8.8 5.6 5.8 3.9 5.7 6.0 3.4 7.1 5.2 5.4 5.9 3.2 5.6 6.7 5.8 1.5 6.2 6.6 3.1 4.9 3.9 7.1 7.9 9.9 9.0 6.1 7.6 7.9 9.0 7.9 7.2 8.2 7.2 26.2 28.9 29.5 41.1 45.2 32.0 20.7 13.3 23.3 28.6 15.3 16.5 40.1 14.3 10.5 27.6 35.5 26.6 32.0 18.0 0.0 17.0 39.6 16.7 22.9 29.9 18.7 25.2 45.1 14.7 36.8 23.2 19.9 16.7 22.1 18.0 19.6 14.5 19.8 26.9 54.4 14.6 8.2 21.3 24.2 22.0 27.4 25.3 24.9 71.2 25.7 27.0 53.5 43.2 63.9 15.0 5.9 28.6 37.7 14.1 20.5 4.5 16.3 47.8 26.3 39.3 31.0 58.9 46.2 16.4 43.0 20.0 48.6 16.4 16.5 17.6 TAF9 "AD-004, CGI-137, MGC1603, MGC3647, MGC5067, TAF2G, TAFII31, TAFII32, TAFIID32" ENSG00000273841 "TATA-box binding protein associated factor 9" Q16594 5 69364743-69370013 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 550.8;Late spermatids: 924.3;Spermatocytes: 370.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028930, HPA053429, HPA058961, HPA072658" Approved Enhanced Nucleoplasm NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "HPA028930: AB_2672832, HPA053429: AB_2682148, HPA058961: AB_2683863, HPA072658: " "unprognostic (1.25e-3)" "unprognostic (9.52e-2)" "unprognostic (1.76e-3)" "unprognostic (8.38e-3)" "unprognostic (5.40e-2)" "unprognostic (1.77e-2)" "prognostic unfavorable (1.48e-5)" "unprognostic (1.19e-1)" "unprognostic (1.69e-1)" "unprognostic (1.66e-1)" "unprognostic (9.45e-2)" "unprognostic (2.71e-1)" "prognostic unfavorable (9.20e-4)" "unprognostic (2.58e-1)" "unprognostic (1.97e-1)" "unprognostic (3.02e-2)" "unprognostic (1.79e-1)" 42.1 43.5 35.5 31.9 38.6 108.2 46.0 35.4 41.4 28.3 34.4 42.5 34.2 31.5 50.4 37.4 31.1 28.8 52.7 39.2 43.0 38.4 55.7 27.7 46.6 37.1 36.4 37.8 40.8 35.5 50.6 38.0 40.5 33.7 47.5 47.2 34.7 27.7 58.0 36.1 33.2 35.9 36.6 35.0 38.0 140.4 37.7 50.9 28.7 41.7 52.3 50.6 30.3 36.1 107.0 109.3 67.7 121.6 114.4 143.5 179.3 100.1 159.8 172.3 227.0 109.7 135.1 135.9 70.2 146.7 322.2 82.2 92.4 208.1 227.4 65.6 111.0 120.4 154.0 157.8 261.3 118.7 168.3 159.4 137.4 117.1 247.7 122.5 143.1 121.4 122.4 119.8 165.9 147.7 126.1 189.5 82.0 42.6 81.6 83.0 119.7 169.0 152.7 120.7 118.1 82.6 108.3 64.3 192.8 111.3 100.9 175.7 103.3 65.9 98.2 78.2 173.1 93.2 118.3 175.6 101.3 145.7 82.8 149.3 107.8 122.5 52.8 101.3 81.2 90.1 79.7 64.2 83.9 75.4 89.6 73.6 16.0 58.7 88.4 47.0 95.5 134.4 35.5 38.6 35.4 41.4 39.2 43.0 37.1 36.4 40.5 36.6 37.7 36.1 67.4 19.2 29.3 0.0 55.2 174.0 151.4 238.7 39.3 24.1 49.9 81.4 69.3 42.9 108.8 23.9 14.6 118.0 45.1 33.8 90.1 67.1 550.8 47.6 44.9 58.6 30.7 93.2 0.0 80.4 166.7 57.3 36.7 38.1 38.6 53.5 34.6 41.9 107.7 20.2 0.0 49.5 146.5 42.8 99.8 924.3 65.3 55.2 99.6 0.0 66.9 35.1 35.0 0.0 0.0 85.1 37.2 34.3 76.5 87.3 47.4 90.2 85.2 43.0 32.9 49.1 95.5 370.7 78.0 60.7 163.2 104.5 50.7 75.0 64.2 149.6 TAGAP "ARHGAP47, FLJ32631, IDDM21" ENSG00000164691 "T cell activation RhoGTPase activating protein" Q8N103 6 159034468-159045152 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 146.6;lymphoid tissue: 47.6" "Cell type enhanced" "Detected in many" "B-cells: 249.5;dendritic cells: 152.3;Macrophages: 91.1;NK-cells: 86.5;Plasma cells: 272.1;T-cells: 223.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 30.1;HMC-1: 42.5;Karpas-707: 43.8;U-266/84: 20.6;U-698: 39.6;U-937: 33.4" "Low region specificity" "Detected in all" "HPA031000, HPA039982" Uncertain Approved Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 59: Non-specific - Transcription" Cytosol "HPA031000: AB_10610560, HPA039982: " "unprognostic (9.86e-3)" "unprognostic (7.55e-2)" "unprognostic (2.41e-2)" "unprognostic (1.56e-2)" "unprognostic (6.36e-2)" "unprognostic (3.10e-3)" "unprognostic (1.04e-1)" "unprognostic (5.25e-2)" "unprognostic (3.35e-3)" "unprognostic (8.39e-2)" "unprognostic (6.19e-2)" "unprognostic (2.41e-1)" "unprognostic (1.49e-1)" "unprognostic (7.25e-2)" "unprognostic (1.15e-1)" "unprognostic (5.24e-2)" "unprognostic (7.39e-2)" 5.0 2.8 1.0 28.9 1.1 146.6 3.9 1.3 2.1 3.4 3.0 5.9 4.4 9.5 2.3 4.1 2.0 6.9 1.6 1.2 3.4 1.3 4.1 8.4 39.6 2.7 2.0 2.2 0.9 0.7 0.8 3.4 2.1 2.8 8.2 1.5 3.0 1.8 0.7 1.2 10.2 26.0 2.2 22.8 7.2 1.6 2.2 24.3 1.6 2.3 47.6 10.0 1.2 4.2 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 30.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 6.2 0.0 0.0 0.0 15.6 42.5 0.3 0.0 0.0 0.0 0.0 0.0 9.0 0.1 43.8 0.0 0.0 4.0 8.2 12.0 0.0 0.0 1.4 0.0 1.4 0.0 0.0 0.3 0.2 0.0 0.1 0.1 1.2 0.0 6.9 0.2 0.0 0.0 0.0 0.0 4.7 20.6 39.6 0.0 33.4 0.0 163.6 27.8 88.4 54.8 20.4 62.6 45.9 73.9 64.6 27.9 46.6 56.9 40.8 169.7 45.6 27.6 9.3 57.5 60.9 1.0 1.1 1.3 2.1 1.2 3.4 2.7 2.0 2.1 2.2 2.2 4.2 5.2 3.2 6.6 0.0 249.5 2.8 0.3 0.2 3.4 0.3 4.4 6.0 0.6 0.0 1.4 0.0 0.0 0.7 152.3 0.2 0.0 0.1 0.3 0.5 0.4 5.2 0.0 8.8 1.2 0.0 0.6 4.3 16.8 0.5 19.0 1.8 1.4 0.8 24.9 0.0 1.0 0.0 0.0 21.9 60.2 1.1 1.2 91.1 28.4 20.6 21.5 0.4 86.5 1.5 0.0 0.0 0.0 22.6 272.1 0.3 0.0 0.3 1.2 0.2 0.0 0.8 2.0 0.1 0.1 2.0 2.7 0.8 223.6 4.6 0.4 0.3 TAGLN2 "HA1756, KIAA0120" ENSG00000158710 "Transgelin 2" P37802 1 159918107-159925507 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 2404.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA001925 Approved Approved "Actin filaments,Cytosol" "Intracellular and membrane" NA NA 270000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "Actin filaments" "HPA001925: AB_1857756" "prognostic unfavorable (2.06e-5)" "unprognostic (2.56e-1)" "unprognostic (4.05e-2)" "unprognostic (1.27e-1)" "unprognostic (3.69e-2)" "unprognostic (8.06e-2)" "prognostic unfavorable (7.07e-5)" "unprognostic (4.61e-2)" "unprognostic (1.50e-1)" "unprognostic (3.21e-1)" "unprognostic (3.56e-3)" "unprognostic (2.34e-1)" "prognostic unfavorable (1.92e-10)" "unprognostic (1.81e-1)" "unprognostic (9.22e-2)" "unprognostic (3.95e-2)" "unprognostic (2.50e-2)" 401.9 154.7 103.7 356.0 103.2 437.3 355.4 106.3 115.0 266.6 94.9 337.4 314.3 220.5 94.9 494.0 231.9 282.6 351.1 101.1 152.7 307.9 254.4 687.7 321.1 141.7 117.6 170.9 284.7 81.0 100.0 378.2 122.9 208.5 307.9 46.1 388.7 205.2 83.4 418.2 356.3 254.4 125.2 479.7 698.8 127.0 125.9 309.6 210.2 139.6 386.4 436.1 350.0 114.9 1382.3 723.7 22.3 8.3 266.8 646.6 835.4 760.0 872.6 1635.2 799.8 786.6 1049.3 862.0 628.0 954.9 495.0 1054.3 378.1 1039.9 978.8 974.3 355.5 1140.7 651.8 50.0 322.7 808.2 1221.4 667.4 776.9 1030.4 504.3 1134.7 1029.0 260.3 494.8 578.9 586.1 563.0 378.1 601.2 619.3 947.6 1457.7 2.9 391.7 1275.3 376.6 527.7 340.7 325.6 900.7 1435.1 410.3 1190.6 756.5 814.2 1147.3 955.1 1134.4 876.9 2078.0 230.8 110.6 525.0 1238.3 541.3 603.8 1458.4 742.0 3160.6 558.9 449.7 499.9 866.5 620.0 544.6 1177.7 680.2 321.6 360.3 3746.8 817.6 356.9 1966.4 756.1 2257.9 103.7 103.2 106.3 115.0 101.1 152.7 141.7 117.6 122.9 125.2 125.9 114.9 617.1 179.5 130.5 0.3 507.8 549.1 330.6 454.3 307.9 31.6 257.0 201.8 12.8 121.5 221.4 183.9 18.8 497.4 567.6 371.0 74.3 1273.4 54.3 289.4 145.9 509.6 317.8 197.6 0.1 1206.9 2404.5 405.2 545.3 242.7 418.8 32.0 265.2 64.1 443.7 3.3 0.6 445.5 284.8 285.9 952.4 85.9 118.7 651.5 334.4 16.9 911.4 66.3 186.4 0.5 1.6 877.4 263.2 63.9 393.4 337.5 324.2 208.2 275.9 25.6 184.1 358.3 324.3 14.3 20.7 494.1 572.5 230.4 393.6 136.7 271.7 405.9 TAPT1 FLJ90013 ENSG00000169762 "Transmembrane anterior posterior transformation 1" Q6NXT6 4 16160505-16227410 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Chondrogenesis, Cilium biogenesis/degradation, Differentiation, Host-virus interaction, Osteogenesis" "Developmental protein, Receptor" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 114.7;Late spermatids: 163.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "REH: 45.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042567 Approved Supported Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 25: Spermatids - Spermatogenesis" Centrosome "Nucleoplasm, Cytosol" "HPA042567: AB_2678055" "unprognostic (2.34e-1)" "unprognostic (5.84e-2)" "unprognostic (1.41e-2)" "prognostic favorable (9.75e-4)" "unprognostic (2.43e-1)" "unprognostic (2.56e-2)" "unprognostic (2.32e-3)" "unprognostic (3.15e-3)" "unprognostic (1.54e-1)" "unprognostic (6.30e-2)" "prognostic favorable (5.34e-4)" "unprognostic (7.07e-2)" "prognostic favorable (8.52e-4)" "unprognostic (9.00e-2)" "unprognostic (8.52e-2)" "unprognostic (7.25e-3)" "prognostic favorable (4.18e-4)" 7.4 15.1 17.5 6.0 18.6 25.7 10.0 17.3 22.3 8.2 15.1 8.9 6.4 10.0 9.2 6.1 9.5 6.7 9.1 17.1 17.0 12.4 30.5 11.9 9.6 18.6 17.4 8.1 8.1 13.0 8.5 6.8 18.4 7.4 8.2 24.7 7.6 6.4 35.5 7.7 7.5 9.3 17.4 8.5 7.9 11.1 17.5 12.2 11.5 19.9 8.1 7.6 6.9 19.5 4.9 3.6 6.0 7.0 8.9 6.8 2.5 7.8 6.0 7.4 8.1 4.9 8.5 31.7 8.3 5.0 10.8 4.0 5.2 4.0 9.3 2.9 6.3 6.2 5.0 5.2 8.4 12.6 6.2 4.2 7.7 7.3 5.3 9.1 3.8 19.3 9.7 14.5 7.2 3.5 18.7 10.1 4.0 9.3 8.4 45.0 8.4 5.8 12.0 5.1 10.0 8.0 7.4 6.2 9.5 4.1 11.5 12.3 7.1 6.2 4.1 4.2 10.3 13.9 12.2 24.2 12.4 30.9 7.3 1.1 0.3 0.0 0.2 0.2 0.0 1.0 0.7 0.4 0.5 2.5 0.9 0.7 0.6 0.3 0.3 0.8 0.5 0.3 17.5 18.6 17.3 22.3 17.1 17.0 18.6 17.4 18.4 17.4 17.5 19.5 12.0 32.1 62.6 47.3 20.2 9.1 6.3 4.2 4.0 24.5 15.0 9.9 14.3 10.0 8.7 7.3 114.7 4.2 16.2 11.1 3.9 6.7 79.0 14.2 12.6 12.8 14.4 16.6 42.6 8.2 3.1 10.2 8.6 12.0 2.5 17.5 8.6 46.0 4.2 70.7 43.6 9.8 4.1 10.3 18.9 163.1 9.9 11.1 16.0 45.0 6.5 33.1 8.2 60.8 68.2 9.5 9.4 15.1 8.9 7.1 10.7 8.7 14.4 62.4 6.6 17.0 11.5 33.3 5.7 7.1 8.0 7.0 10.8 16.5 9.0 6.6 TASOR "C3orf63, FAM208A, KIAA1105, RAP140, se89-1, TASOR1" ENSG00000163946 "Transcription activation suppressor" Q9UK61 3 56620133-56683237 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 25.0;Cardiomyocytes: 31.4;Cytotrophoblasts: 14.5;dendritic cells: 12.1;Extravillous trophoblasts: 9.9;Fibroblasts: 10.7;Hofbauer cells: 20.7;Syncytiotrophoblasts: 9.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006735, HPA017142" Uncertain Enhanced Nucleoplasm NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "HPA006735: AB_1852384, HPA017142: AB_1852382" "unprognostic (1.46e-1)" "unprognostic (7.97e-2)" "unprognostic (1.07e-2)" "unprognostic (1.79e-1)" "unprognostic (1.92e-1)" "unprognostic (2.51e-2)" "unprognostic (2.30e-3)" "unprognostic (9.31e-2)" "unprognostic (3.91e-2)" "unprognostic (5.93e-2)" "unprognostic (1.51e-1)" "unprognostic (8.84e-2)" "unprognostic (1.73e-1)" "unprognostic (1.90e-1)" "unprognostic (2.04e-1)" "unprognostic (1.67e-1)" "unprognostic (2.74e-1)" 9.5 8.4 4.0 15.4 8.4 11.8 11.4 8.7 5.3 12.0 1.7 11.7 10.0 12.3 7.4 11.1 13.1 11.7 6.2 2.2 3.6 10.2 7.9 11.3 20.7 5.1 5.6 14.2 12.4 21.1 4.4 9.4 6.0 9.3 12.4 9.9 8.9 9.4 2.6 7.1 11.3 12.3 5.9 14.7 12.8 29.2 4.5 21.3 18.8 6.9 19.3 12.5 3.8 12.0 49.2 19.2 29.2 23.0 15.5 26.7 14.6 21.4 22.0 20.1 21.1 15.8 35.8 77.3 7.9 21.6 33.9 19.1 29.3 25.1 29.2 38.3 14.8 30.4 27.3 7.1 10.9 32.2 46.1 12.9 20.6 19.6 35.1 23.7 26.5 28.8 29.8 43.3 26.0 17.3 39.8 6.4 16.3 25.9 29.0 20.9 28.9 25.9 19.0 35.5 19.3 23.9 46.9 18.5 23.2 16.6 30.6 36.7 28.6 25.9 23.7 23.8 33.1 39.2 58.5 38.6 30.1 46.7 35.0 0.6 0.8 1.1 1.2 0.6 0.7 0.7 1.0 1.2 1.0 1.1 1.1 1.2 0.2 0.9 0.7 0.7 1.0 0.6 4.0 8.4 8.7 5.3 2.2 3.6 5.1 5.6 6.0 5.9 4.5 12.0 25.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.4 0.0 0.0 0.0 0.0 14.5 12.1 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 9.9 10.7 0.0 0.0 0.0 0.0 0.0 0.0 20.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 9.2 2.1 0.0 0.0 0.0 TASP1 "C20orf13, dJ585I14.2, FLJ20212" ENSG00000089123 "Taspase 1" Q9H6P5 20 13389392-13638932 "Predicted intracellular proteins" "Hydrolase, Protease, Threonine protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 136.1;Inhibitory neurons: 131.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030824, HPA030825" Uncertain Approved "Plasma membrane" No No "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA030824: AB_10600327, HPA030825: AB_10601575" "unprognostic (1.29e-1)" "unprognostic (1.68e-1)" "unprognostic (8.61e-2)" "unprognostic (1.20e-1)" "unprognostic (2.47e-1)" "unprognostic (6.46e-2)" "unprognostic (3.44e-3)" "unprognostic (9.85e-2)" "unprognostic (9.85e-2)" "unprognostic (6.95e-2)" "unprognostic (1.59e-1)" "unprognostic (3.13e-2)" "unprognostic (2.21e-1)" "unprognostic (1.04e-1)" "unprognostic (2.70e-1)" "prognostic unfavorable (6.78e-4)" "unprognostic (1.67e-2)" 7.0 4.5 1.0 4.3 1.7 4.9 6.8 1.5 2.9 6.5 3.9 5.2 3.7 6.8 6.0 4.8 8.1 4.5 5.7 1.2 2.7 5.4 4.5 6.0 5.7 1.3 1.7 5.6 5.9 8.7 7.4 6.5 1.0 5.2 5.7 6.4 6.0 4.6 2.9 5.5 4.6 5.1 0.5 5.6 5.6 6.1 2.3 12.5 7.8 4.3 5.2 5.6 6.2 2.9 13.1 7.7 3.1 3.7 3.6 5.6 6.0 5.3 7.6 6.1 7.1 16.0 13.3 5.9 3.6 7.0 6.7 17.2 4.9 18.4 7.1 3.5 5.8 11.8 4.7 20.3 7.4 16.0 4.1 6.3 12.1 6.2 15.0 3.7 6.1 10.4 10.7 0.2 5.4 15.8 30.7 8.7 4.2 11.7 3.5 4.8 12.7 9.1 8.5 9.8 8.3 5.7 8.2 15.8 10.2 4.4 8.3 5.8 5.9 5.7 4.0 5.9 7.6 11.3 16.7 4.2 3.2 3.6 5.5 2.3 4.5 4.9 12.7 6.5 9.0 12.1 12.8 10.0 5.0 9.8 18.6 14.4 2.5 14.8 6.5 19.5 13.3 7.1 1.0 1.7 1.5 2.9 1.2 2.7 1.3 1.7 1.0 0.5 2.3 2.9 10.7 6.4 7.7 31.3 19.6 14.1 13.2 11.1 24.5 14.9 10.0 8.8 6.4 17.2 8.8 5.5 10.4 12.0 13.8 3.9 7.9 12.1 20.1 15.7 10.6 6.6 3.6 7.8 136.1 6.0 12.3 15.9 13.3 9.5 15.2 5.2 3.6 6.4 4.7 11.8 131.0 9.9 4.1 3.0 4.7 4.8 3.4 5.8 10.6 35.6 2.9 6.6 11.3 50.3 49.6 8.6 11.4 3.4 13.3 8.0 5.3 12.2 23.5 17.0 6.6 23.7 17.0 29.3 9.3 18.0 12.1 7.0 12.7 10.2 7.7 8.9 TBC1D21 "MGC34741, MgcRabGAP" ENSG00000167139 "TBC1 domain family member 21" Q8IYX1 15 73873564-73889214 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 238 "testis: 49.7" "Group enriched" "Detected in some" 112 "Early spermatids: 401.0;Late spermatids: 1080.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA043319 Enhanced NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 31: Spermatids - Spermatogenesis" "HPA043319: AB_10966214" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 49.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 401.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1080.9 5.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 5.7 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TBC1D28 FLJ40244 ENSG00000189375 "TBC1 domain family member 28" Q2M2D7 17 18634247-18644427 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 46 "testis: 22.2" "Group enriched" "Detected in some" 66 "Early spermatids: 63.0;Late spermatids: 16.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" "unprognostic (2.56e-1)" 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 22.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.3 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 63.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 16.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TBCCD1 FLJ10560 ENSG00000113838 "TBCC domain containing 1" Q9NVR7 3 186546067-186570543 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 42.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "unprognostic (1.15e-1)" "unprognostic (7.41e-3)" "unprognostic (6.36e-2)" "unprognostic (2.62e-2)" "unprognostic (8.79e-2)" "unprognostic (7.14e-2)" "prognostic unfavorable (1.87e-4)" "unprognostic (2.10e-2)" "unprognostic (1.42e-2)" "unprognostic (2.72e-2)" "unprognostic (2.59e-3)" "unprognostic (1.14e-1)" "unprognostic (1.43e-1)" "unprognostic (2.91e-1)" "unprognostic (1.62e-1)" "unprognostic (1.15e-1)" "unprognostic (2.27e-1)" 6.7 5.9 4.7 7.5 5.6 7.5 6.7 6.4 5.3 6.4 6.8 6.5 6.4 7.1 7.5 7.7 5.7 6.2 5.4 4.5 5.6 6.2 9.5 5.4 9.4 5.3 5.3 6.3 7.5 8.5 4.2 7.6 5.8 5.2 7.3 12.5 6.4 5.3 6.1 6.9 6.1 6.3 5.3 6.6 6.1 19.2 5.3 10.9 8.4 7.4 9.2 6.6 6.5 6.8 12.5 8.7 13.8 13.7 11.6 12.4 9.8 9.5 6.9 12.2 12.9 15.3 9.6 15.3 24.5 6.9 9.5 13.2 21.3 9.0 15.6 22.2 10.9 19.5 7.7 9.5 6.6 18.4 12.7 7.4 9.5 10.8 12.5 8.0 17.3 19.9 15.9 14.3 10.8 15.0 17.9 10.6 8.6 28.4 15.1 20.3 13.8 17.1 8.0 7.7 16.2 10.4 17.0 18.9 10.1 10.8 24.7 11.6 10.7 8.4 10.7 10.5 15.0 19.8 36.9 37.0 9.0 16.4 16.5 17.3 9.7 11.7 11.7 9.7 15.3 11.8 12.9 13.2 12.8 11.3 10.2 13.0 4.2 14.6 11.3 7.5 18.0 9.1 4.7 5.6 6.4 5.3 4.5 5.6 5.3 5.3 5.8 5.3 5.3 6.8 5.6 16.0 3.7 8.5 8.8 6.4 2.8 2.6 9.1 6.5 3.2 2.4 2.6 4.3 1.9 1.8 2.1 4.0 2.9 4.1 11.7 7.1 3.0 3.7 4.9 5.3 3.6 5.9 11.5 6.5 6.0 4.7 12.2 3.5 12.0 4.2 6.8 5.2 4.7 0.0 13.2 6.6 0.0 3.8 6.4 2.8 5.9 4.2 5.4 7.5 4.6 5.2 9.2 12.5 14.1 4.8 5.0 3.8 11.5 2.2 5.4 3.5 7.0 6.7 6.6 4.2 4.8 42.1 20.8 9.7 4.1 4.1 7.2 3.3 5.5 1.9 TBL1X "EBI, TBL1" ENSG00000101849 "Transducin beta like 1 X-linked" O60907 X 9463295-9741037 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" Activator "Congenital hypothyroidism, Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 103.8;Oligodendrocytes: 109.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 18.7" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "CAB005363, HPA067703" Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 36: Stromal cells - Cell proliferation" Nucleoplasm Nucleoli "CAB005363: AB_2240272, HPA067703: AB_2685892" "prognostic unfavorable (8.50e-4)" "unprognostic (2.03e-1)" "unprognostic (2.12e-1)" "unprognostic (2.89e-2)" "unprognostic (2.44e-1)" "unprognostic (1.40e-2)" "unprognostic (2.21e-3)" "unprognostic (3.09e-1)" "unprognostic (2.70e-1)" "unprognostic (3.27e-1)" "prognostic favorable (1.32e-4)" "unprognostic (2.66e-1)" "prognostic favorable (4.58e-4)" "unprognostic (6.71e-2)" "unprognostic (6.38e-2)" "unprognostic (3.40e-3)" "unprognostic (1.53e-1)" 9.3 9.1 20.0 8.7 21.3 7.2 9.7 17.4 16.7 18.1 14.2 9.4 2.8 38.4 35.3 10.2 16.6 7.1 7.3 16.7 21.1 16.6 13.6 5.8 9.0 23.8 20.2 18.0 9.2 23.9 18.7 20.7 19.7 25.4 5.3 16.5 7.3 43.2 4.6 7.5 5.0 26.6 18.6 8.4 8.1 9.7 26.7 18.4 12.0 5.2 10.2 13.5 12.7 20.0 0.1 29.6 18.5 49.2 16.8 17.4 18.4 11.3 25.0 21.3 22.2 22.4 20.2 31.6 0.8 22.7 9.1 6.7 40.7 8.9 30.9 13.0 19.6 20.0 35.6 26.5 23.7 7.2 68.6 15.6 10.1 22.3 11.8 11.7 19.9 17.2 35.8 53.5 12.5 25.6 17.8 27.2 36.7 14.2 31.5 39.3 14.5 39.3 28.9 16.9 23.4 10.6 27.2 6.8 16.9 48.2 13.3 15.6 29.1 7.5 18.3 0.8 4.6 32.6 27.8 25.1 27.2 17.4 7.1 6.3 4.7 5.7 2.2 2.9 1.8 2.2 1.7 2.0 3.5 3.6 3.1 2.9 18.7 0.3 2.0 0.3 2.9 2.1 20.0 21.3 17.4 16.7 16.7 21.1 23.8 20.2 19.7 18.6 26.7 20.0 12.6 0.0 4.5 103.8 17.3 6.5 13.2 3.8 9.1 11.8 19.1 18.0 10.1 20.0 6.8 31.3 22.9 78.1 20.4 7.9 13.7 10.7 1.0 34.4 80.7 10.3 22.8 3.8 12.5 7.8 6.0 13.1 9.7 51.1 11.4 32.5 11.4 64.3 11.3 6.7 17.1 5.4 2.0 33.0 22.8 3.2 14.3 19.7 5.4 61.8 37.5 46.6 19.6 46.3 109.7 7.5 7.9 28.6 9.5 24.1 0.2 21.8 10.0 24.5 0.0 9.4 27.9 1.4 18.0 16.5 12.4 45.0 18.8 22.3 4.9 23.7 TBX18 ENSG00000112837 "T-box transcription factor 18" O95935 6 84687351-84764598 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 10.3" "Cell type enriched" "Detected in some" 5 "Microglial cells: 91.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 57.4;ASC diff: 39.0;ASC TERT1: 40.4;RH-30: 37.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA006807 Supported Nucleoplasm NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm "HPA006807: " "unprognostic (8.04e-2)" "unprognostic (7.06e-3)" "unprognostic (9.71e-2)" "unprognostic (2.31e-1)" "unprognostic (4.00e-1)" "unprognostic (1.62e-1)" "unprognostic (2.19e-1)" "unprognostic (3.24e-1)" "unprognostic (2.57e-1)" "unprognostic (7.92e-2)" "unprognostic (3.50e-1)" "unprognostic (1.12e-1)" "unprognostic (1.88e-14)" "unprognostic (4.81e-5)" "unprognostic (1.86e-1)" "unprognostic (3.07e-3)" "unprognostic (1.78e-1)" 10.3 2.0 1.6 0.9 3.1 0.0 6.1 1.1 3.4 1.9 4.6 0.7 0.1 1.4 0.4 3.1 1.8 1.5 6.6 1.3 1.3 0.4 0.2 0.3 1.8 1.7 1.2 2.7 0.5 0.4 1.6 1.8 1.6 0.6 0.4 0.1 1.6 1.1 1.3 4.7 1.1 0.5 1.5 0.0 0.4 1.0 2.1 0.6 1.7 1.4 0.2 4.5 2.9 1.7 0.0 57.4 0.0 0.0 39.0 40.4 0.0 23.5 11.5 17.4 16.5 0.4 0.0 0.1 0.0 9.8 0.0 3.0 0.0 13.8 14.0 0.0 23.2 0.0 0.0 0.0 5.0 0.0 23.1 17.1 1.3 12.1 25.8 0.0 20.2 0.0 30.7 0.2 12.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 37.3 0.0 0.3 0.0 0.2 1.2 0.0 1.0 9.0 1.4 0.0 31.0 18.2 0.0 4.8 17.6 0.0 0.3 0.0 0.0 10.9 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 3.1 1.1 3.4 1.3 1.3 1.7 1.2 1.6 1.5 2.1 1.7 1.6 0.0 0.0 0.3 0.0 5.5 0.0 0.4 0.0 0.0 0.2 0.3 2.3 0.0 0.3 0.0 0.0 0.1 0.1 0.2 0.0 0.0 6.9 0.0 0.1 1.6 0.0 0.0 0.1 0.0 0.0 14.9 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.1 0.4 0.0 2.1 6.1 2.3 1.2 0.1 8.8 91.8 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.4 0.0 0.0 1.0 0.1 0.2 0.1 0.0 1.6 16.9 0.4 3.1 0.1 4.4 0.1 0.8 0.8 0.3 0.0 TBXAS1 "CYP5, CYP5A1, THAS, TS, TXAS, TXS" ENSG00000059377 "Thromboxane A synthase 1" P24557 7 139777051-140020325 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Isomerase, Lyase, Monooxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 57.8" "Group enriched" "Detected in many" 4 "granulocytes: 71.0;Hofbauer cells: 88.8;Kupffer cells: 193.6;Macrophages: 132.9;Microglial cells: 191.1;monocytes: 63.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 14 "basophil: 324.3;classical monocyte: 322.4;eosinophil: 333.6;intermediate monocyte: 466.0;myeloid DC: 129.0;neutrophil: 271.1;non-classical monocyte: 423.1" "Group enriched" "Detected in all" 22 "dendritic cells: 129.0;granulocytes: 333.6;monocytes: 466.0" "Cell line enhanced" "Detected in many" "NB-4: 76.7;PC-3: 23.7;RPTEC TERT1: 21.0;U-937: 60.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" "HPA031257, HPA031258, HPA031259" Enhanced Approved "Endoplasmic reticulum,Cytosol" NA NA 890000 "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 4: Macrophages - Innate immune response" "Endoplasmic reticulum, Cytosol" "HPA031257: AB_2673812, HPA031258: AB_2673813, HPA031259: AB_2673814" "unprognostic (4.46e-2)" "unprognostic (3.07e-1)" "unprognostic (8.80e-2)" "unprognostic (1.12e-1)" "unprognostic (2.72e-1)" "unprognostic (9.41e-2)" "unprognostic (5.10e-2)" "unprognostic (3.12e-1)" "unprognostic (2.38e-1)" "unprognostic (3.07e-2)" "unprognostic (1.11e-1)" "unprognostic (3.03e-2)" "prognostic unfavorable (1.14e-4)" "unprognostic (1.52e-1)" "unprognostic (5.00e-3)" "unprognostic (8.53e-2)" "unprognostic (5.34e-2)" 13.2 10.8 5.3 28.1 5.1 24.8 8.2 5.4 5.9 5.4 5.8 10.1 10.3 3.2 2.0 5.4 4.9 21.2 3.3 4.5 6.8 5.8 12.8 23.9 12.4 10.0 6.6 2.9 3.6 2.9 2.3 14.2 8.8 6.4 13.0 1.6 9.0 4.0 1.0 1.3 11.9 12.6 8.9 57.8 11.2 1.4 9.7 15.1 1.8 3.3 8.3 13.9 2.1 14.7 0.2 5.4 0.3 0.1 1.2 3.9 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 12.1 0.0 0.3 0.0 0.0 0.0 0.0 9.4 0.7 17.8 0.0 0.0 1.6 6.2 15.3 2.1 0.0 0.0 0.9 1.1 2.3 0.1 0.6 2.2 0.6 0.2 2.4 76.7 0.2 18.0 23.7 2.6 0.0 1.2 21.0 0.0 0.2 1.1 0.2 0.0 0.8 0.0 0.0 14.4 2.0 0.6 0.2 1.4 1.0 4.6 0.9 0.3 0.4 60.8 1.7 324.3 322.4 333.6 7.3 466.0 11.9 8.3 13.5 3.7 129.0 4.5 2.3 1.3 271.1 11.9 423.1 22.6 13.9 216.7 5.3 5.1 5.4 5.9 4.5 6.8 10.0 6.6 8.8 8.9 9.7 14.7 3.9 3.2 10.8 8.1 9.9 0.4 1.2 0.5 2.8 1.0 3.0 3.0 1.1 5.7 1.7 1.8 6.2 0.6 16.4 0.8 9.8 5.2 0.4 1.0 0.6 5.0 1.8 12.8 1.2 9.5 0.5 2.9 7.1 3.8 71.0 0.5 16.8 8.6 88.8 3.3 1.8 1.9 12.2 193.6 19.5 0.7 0.3 132.9 3.6 191.1 63.7 4.9 26.8 3.0 5.9 4.4 7.9 0.0 16.4 5.8 0.2 6.3 1.0 4.1 19.7 1.3 1.7 0.5 0.7 26.2 0.6 0.5 13.4 0.3 2.7 1.2 TCF7 TCF-1 ENSG00000081059 "Transcription factor 7" P36402 5 134114681-134151865 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Wnt signaling pathway" "Activator, DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 14 "lymphoid tissue: 604.3" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 73.0;T-cells: 108.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "MAIT T-cell: 28.8;memory CD4 T-cell: 49.7;memory CD8 T-cell: 29.0;naive CD4 T-cell: 97.2;naive CD8 T-cell: 62.3;NK-cell: 43.0" "Group enriched" "Detected in many" 20 "NK-cells: 43.0;T-cells: 97.2" "Cell line enriched" "Detected in many" 6 "MOLT-4: 1324.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019403, HPA058863, HPA070505" Enhanced Enhanced Nucleoplasm NA NA "Cluster 32: T-cells - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm "CAB019403: AB_2199302, HPA058863: AB_2683837, HPA070505: AB_2686275" "unprognostic (3.63e-3)" "unprognostic (1.98e-3)" "unprognostic (1.03e-1)" "unprognostic (5.08e-3)" "unprognostic (1.70e-1)" "unprognostic (6.74e-2)" "unprognostic (1.12e-1)" "unprognostic (6.38e-2)" "unprognostic (2.31e-1)" "unprognostic (1.65e-1)" "unprognostic (5.35e-2)" "unprognostic (2.32e-1)" "unprognostic (3.04e-1)" "unprognostic (1.50e-2)" "unprognostic (2.33e-2)" "unprognostic (1.90e-1)" "unprognostic (4.10e-2)" 4.1 5.3 2.0 56.4 1.8 16.4 4.0 1.8 1.9 3.2 21.3 5.8 16.0 3.9 41.5 3.5 43.1 6.2 2.4 3.1 1.5 4.0 5.8 5.6 94.4 5.9 2.7 1.8 9.4 2.1 6.4 3.5 2.2 5.0 6.8 1.5 8.0 3.5 1.4 4.3 20.4 1.8 3.8 34.6 11.0 3.4 2.1 604.3 6.3 1.0 70.0 9.8 2.0 2.6 0.2 7.8 8.2 29.2 3.9 16.2 11.4 2.2 4.4 0.7 0.8 61.6 19.3 0.4 14.0 13.4 32.3 1.0 13.1 3.1 0.6 3.0 12.2 0.2 7.4 46.4 0.4 0.4 1.6 1.1 0.1 12.6 0.7 5.7 1.8 218.2 7.9 0.3 1.3 0.7 1324.2 1.4 9.0 19.2 10.4 1.6 0.0 1.4 3.0 1.4 3.4 25.1 6.0 1.8 1.6 6.4 1.6 7.3 1.9 81.2 0.5 37.0 2.8 1.3 0.1 0.4 42.7 0.5 4.1 2.2 0.3 3.2 12.3 0.2 28.8 3.5 49.7 29.0 0.2 1.4 97.2 62.3 1.9 43.0 0.2 0.5 6.5 21.8 2.0 1.8 1.8 1.9 3.1 1.5 5.9 2.7 2.2 3.8 2.1 2.6 6.0 3.2 1.9 4.6 27.3 15.7 27.9 6.9 2.8 28.6 14.5 14.9 3.1 10.0 2.9 3.7 73.0 21.6 47.4 18.4 0.0 6.1 3.8 57.6 30.4 9.6 12.6 5.3 2.4 9.9 30.5 11.7 6.6 35.8 20.3 12.1 6.8 3.0 7.1 10.1 2.0 17.0 6.1 9.7 20.0 2.3 6.2 8.7 10.6 1.0 17.1 12.4 41.2 3.5 4.1 23.6 18.5 4.5 9.3 24.6 50.8 1.4 2.5 58.4 0.0 61.4 16.1 4.0 11.0 3.3 11.4 30.0 108.3 8.6 24.1 14.9 TCTN2 "C12orf38, FLJ12975, JBTS24, MKS8, TECT2" ENSG00000168778 "Tectonic family member 2" Q96GX1 12 123671110-123708399 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation" "Ciliopathy, Joubert syndrome, Meckel syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 27.6;Respiratory ciliated cells: 32.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039900 Enhanced Approved "Golgi apparatus,Vesicles" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "Golgi apparatus, Vesicles" "HPA039900: AB_10673366" "unprognostic (3.46e-2)" "unprognostic (1.03e-1)" "unprognostic (1.30e-2)" "unprognostic (1.45e-2)" "unprognostic (1.63e-3)" "unprognostic (1.32e-1)" "unprognostic (3.09e-3)" "unprognostic (3.14e-2)" "unprognostic (7.05e-2)" "unprognostic (1.09e-1)" "unprognostic (3.97e-3)" "unprognostic (2.23e-1)" "unprognostic (1.69e-1)" "unprognostic (2.79e-1)" "unprognostic (2.46e-1)" "unprognostic (7.86e-2)" "unprognostic (2.68e-1)" 5.3 4.4 5.5 2.6 6.4 1.9 7.2 5.8 5.3 10.0 30.4 5.7 2.1 11.0 11.0 3.4 28.5 6.4 4.8 4.9 9.5 10.0 1.4 8.3 3.3 8.4 11.5 14.7 6.9 14.1 16.3 4.6 6.5 9.6 4.0 17.6 9.1 8.6 1.7 8.3 3.8 6.0 7.1 4.1 5.4 11.1 8.7 2.5 12.4 2.1 3.0 5.2 6.7 4.1 14.9 15.1 10.7 15.6 15.0 16.5 13.1 5.4 10.9 11.5 8.7 7.9 14.5 0.5 9.2 8.9 10.0 19.6 6.2 4.9 11.2 2.5 7.6 1.2 10.6 7.2 5.0 3.7 4.8 8.0 8.8 16.3 4.8 34.9 15.7 5.1 7.1 0.3 7.1 7.9 4.5 7.4 6.8 5.9 9.1 4.0 10.8 1.5 13.7 11.1 6.5 8.3 18.2 6.0 8.4 11.0 25.5 5.6 9.8 16.0 8.2 14.7 7.1 4.3 8.9 1.4 20.9 0.4 9.7 1.7 0.2 1.2 1.9 0.6 2.7 1.9 2.2 2.0 0.4 2.1 2.4 2.4 0.3 0.8 0.5 2.5 1.4 0.2 5.5 6.4 5.8 5.3 4.9 9.5 8.4 11.5 6.5 7.1 8.7 4.1 2.7 3.2 5.3 6.5 1.8 4.1 2.3 2.6 1.2 4.4 4.8 2.3 3.8 5.7 3.9 7.3 12.5 2.8 2.1 1.2 0.0 2.9 6.1 27.6 5.0 1.7 1.2 2.5 10.4 2.1 3.0 4.6 2.6 4.3 3.8 5.0 2.9 0.4 1.3 0.0 14.4 1.8 2.0 0.3 1.2 2.8 2.5 1.0 5.4 2.8 1.4 4.6 1.0 2.5 1.3 2.0 0.8 4.9 1.1 1.4 0.2 1.9 32.1 14.5 0.0 6.0 2.7 11.5 10.9 0.6 2.3 1.1 2.4 2.3 3.0 1.0 TDRD1 CT41.1 ENSG00000095627 "Tudor domain containing 1" Q9BXT4 10 114179270-114232304 "Plasma proteins, Predicted intracellular proteins" "Differentiation, Meiosis, RNA-mediated gene silencing, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "testis: 17.5" "Cell type enhanced" "Detected in some" "Early spermatids: 7.1;Late spermatids: 5.3;Spermatocytes: 25.6;Spermatogonia: 25.5" "Cancer enriched" "Detected in some" 5 "prostate cancer: 4.1" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.4" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 4 "SK-BR-3: 51.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA037729 Enhanced NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 83: Testis - Spermatogenesis" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "HPA037729: AB_10670527" "unprognostic (6.77e-2)" "unprognostic (2.73e-1)" "unprognostic (1.06e-1)" "unprognostic (1.68e-1)" "unprognostic (1.10e-2)" "unprognostic (1.26e-2)" "unprognostic (3.96e-2)" "unprognostic (3.15e-2)" "unprognostic (6.13e-2)" "unprognostic (1.55e-1)" "unprognostic (1.82e-1)" "unprognostic (1.51e-2)" "unprognostic (9.60e-2)" "unprognostic (3.98e-2)" "unprognostic (4.75e-1)" "unprognostic (1.68e-1)" 0.2 0.0 0.2 0.1 0.3 0.0 0.3 0.1 0.6 0.1 0.2 0.1 0.2 0.1 0.0 0.2 0.2 0.1 0.6 0.1 0.2 2.0 0.2 0.0 0.2 0.3 0.3 0.4 0.5 0.0 0.0 0.0 0.2 0.6 0.1 0.0 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.5 0.1 17.5 0.3 0.2 0.1 0.5 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.3 0.0 0.0 0.0 0.0 0.0 0.0 10.9 0.0 0.0 0.0 0.0 0.0 0.0 51.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.1 0.0 1.4 0.0 0.0 0.2 0.3 0.1 0.6 0.1 0.2 0.3 0.3 0.2 0.1 0.3 0.4 0.6 0.0 0.5 0.0 0.0 0.3 0.0 0.1 0.0 0.0 1.1 0.9 3.5 2.8 0.0 0.0 0.0 0.3 2.7 0.3 0.0 0.2 7.1 0.4 0.5 0.2 0.0 0.0 0.5 0.6 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 2.0 0.0 0.3 5.3 2.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.7 0.0 0.0 0.0 1.2 2.7 0.0 0.0 0.5 0.5 25.6 25.5 0.0 0.0 0.1 0.1 0.7 0.1 0.0 TDRD5 "FLJ34823, TUDOR3" ENSG00000162782 "Tudor domain containing 5" Q8NAT2 1 179591613-179691272 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 6.5;testis: 21.9" "Group enriched" "Detected in some" 4 "Early spermatids: 36.1;Late spermatids: 12.1;Spermatocytes: 26.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MCF7: 3.7;SK-BR-3: 5.8;T-47d: 10.3;U-266/70: 14.3;U-266/84: 13.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" HPA029418 Enhanced NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 29: Early spermatids - Spermatogenesis" "HPA029418: AB_10603035" "unprognostic (1.87e-1)" "unprognostic (1.43e-1)" "unprognostic (2.08e-1)" "unprognostic (2.15e-4)" "unprognostic (3.96e-1)" "unprognostic (4.39e-3)" "unprognostic (4.41e-4)" "unprognostic (3.18e-1)" "unprognostic (4.30e-1)" "unprognostic (3.75e-2)" "unprognostic (1.18e-1)" "unprognostic (3.37e-1)" "unprognostic (1.44e-2)" "unprognostic (1.28e-1)" "unprognostic (2.78e-2)" "unprognostic (6.89e-2)" "unprognostic (2.31e-1)" 0.2 0.3 0.8 0.1 1.4 0.3 3.6 0.0 0.8 0.1 0.0 0.6 0.5 0.0 6.5 0.5 0.9 0.2 0.0 0.7 0.4 1.8 0.0 0.1 0.0 0.9 0.9 0.0 0.2 0.3 2.3 0.2 1.0 0.6 0.7 0.3 0.8 0.3 0.0 0.3 0.4 0.0 0.6 0.0 0.3 21.9 1.1 0.1 0.8 0.0 0.4 0.3 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 3.7 0.0 0.0 1.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 5.8 0.0 0.7 10.3 0.2 0.0 0.0 1.5 0.0 0.0 14.3 13.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.4 0.0 0.8 0.7 0.4 0.9 0.9 1.0 0.6 1.1 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 3.5 1.8 0.7 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.1 36.1 1.0 0.0 0.1 0.0 0.0 5.2 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.9 0.0 0.0 0.0 12.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 1.1 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.4 5.7 0.0 0.3 0.0 0.0 0.0 0.3 0.1 TDRD6 "bA446F17.4, CT41.2, NY-CO-45, SPATA36" ENSG00000180113 "Tudor domain containing 6" O60522 6 46687875-46704319 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 30.3" "Group enriched" "Detected in many" 4 "Early spermatids: 224.8;Spermatocytes: 82.7" "Cancer enhanced" "Detected in some" "prostate cancer: 2.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HeLa: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA075923, HPA077353" Enhanced Approved "Vesicles,Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 21: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 29: Early spermatids - Spermatogenesis" "Microtubules, Cytokinetic bridge, Mitotic spindle" Vesicles "HPA075923: , HPA077353: " "unprognostic (2.01e-1)" "unprognostic (7.41e-3)" "unprognostic (7.25e-3)" "unprognostic (3.88e-2)" "unprognostic (3.54e-1)" "unprognostic (4.10e-2)" "unprognostic (1.03e-1)" "unprognostic (4.32e-2)" "unprognostic (7.97e-2)" "unprognostic (2.50e-1)" "unprognostic (2.20e-3)" "unprognostic (2.20e-1)" "unprognostic (2.79e-1)" "unprognostic (2.86e-1)" "unprognostic (2.00e-1)" "unprognostic (2.16e-2)" "unprognostic (4.38e-3)" 0.7 1.7 3.3 3.0 5.1 0.2 0.8 7.8 5.4 1.2 1.8 1.0 0.7 0.9 3.4 0.6 0.8 2.2 1.6 4.1 2.6 2.1 2.5 0.7 4.0 3.9 3.2 1.1 1.1 0.4 3.0 1.6 4.1 2.0 0.3 8.9 1.3 0.6 2.3 3.5 0.7 0.4 2.7 2.5 0.8 30.3 3.7 0.0 5.6 0.1 0.1 1.1 0.8 4.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.3 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.0 0.2 0.2 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 5.1 7.8 5.4 4.1 2.6 3.9 3.2 4.1 2.7 3.7 4.0 0.8 9.6 0.5 3.9 0.0 0.5 0.4 0.1 1.2 11.3 0.4 0.8 3.4 0.0 3.8 7.3 6.2 0.0 0.0 0.0 1.9 0.3 224.8 1.0 2.2 1.2 4.2 0.0 13.6 0.2 0.0 1.0 0.0 0.7 0.0 0.4 0.7 3.0 0.1 5.0 14.7 0.3 0.0 0.3 0.0 33.8 4.1 0.5 3.6 6.5 0.0 1.1 0.0 14.6 17.8 0.1 0.0 4.5 0.0 0.6 0.4 0.4 0.2 7.5 13.1 3.0 0.5 82.7 34.7 0.0 1.6 0.0 0.0 1.4 0.5 0.2 TEC PSCTK4 ENSG00000135605 "Tec protein tyrosine kinase" P42680 4 48135783-48269838 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 13.9;Glandular and luminal cells: 25.1;granulocytes: 19.6;Plasma cells: 15.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 5 "basophil: 20.7;eosinophil: 13.3" "Lineage enriched" "Detected in many" 6 "granulocytes: 20.7" "Cell line enhanced" "Detected in many" "HEL: 13.5;HMC-1: 20.3;U-266/70: 20.3;U-266/84: 15.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA005733, HPA024657" Approved Supported "Plasma membrane" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 29: U-266 - Adaptive immune response" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "HPA005733: AB_1857878, HPA024657: AB_2671637" "unprognostic (7.19e-2)" "unprognostic (1.44e-1)" "unprognostic (1.41e-2)" "unprognostic (4.07e-3)" "unprognostic (4.21e-2)" "unprognostic (8.57e-2)" "unprognostic (3.14e-1)" "unprognostic (1.67e-1)" "unprognostic (8.36e-2)" "prognostic favorable (7.12e-4)" "unprognostic (7.46e-3)" "unprognostic (7.83e-2)" "unprognostic (1.01e-4)" "unprognostic (4.24e-2)" "unprognostic (2.16e-1)" "unprognostic (7.39e-2)" "unprognostic (4.96e-3)" 0.9 1.7 0.1 2.1 0.2 6.1 1.4 0.1 0.4 1.2 1.0 1.3 1.6 1.1 4.2 3.4 1.9 1.1 1.3 0.0 0.4 1.1 2.5 2.0 3.1 1.1 0.3 0.4 0.8 1.2 0.6 1.1 1.1 0.5 1.3 1.8 2.3 1.0 0.6 3.6 1.5 0.8 0.3 1.7 1.1 1.2 0.7 2.0 1.3 0.5 3.3 1.0 1.6 0.2 3.0 0.8 0.0 0.0 0.0 0.0 0.1 0.5 2.2 1.3 2.7 0.0 2.2 1.9 2.0 0.0 0.1 0.6 1.1 0.0 1.8 0.1 0.8 13.5 1.0 0.1 0.0 2.2 20.3 0.0 0.3 1.7 0.0 1.4 0.0 0.6 7.5 0.5 4.1 1.0 1.3 4.9 0.4 1.4 0.8 3.1 2.7 0.0 3.4 0.9 0.0 0.2 0.6 0.3 0.5 1.1 0.7 4.2 0.0 0.0 0.0 2.8 0.0 20.3 15.4 2.6 0.0 3.0 0.1 20.7 0.6 13.3 0.1 0.7 0.3 1.0 0.2 0.5 1.5 0.7 0.5 0.5 0.5 3.6 0.1 0.1 0.1 0.4 0.1 0.2 0.1 0.4 0.0 0.4 1.1 0.3 1.1 0.3 0.7 0.2 0.6 6.4 6.8 0.7 6.8 2.5 1.7 0.2 2.8 0.9 1.7 1.1 1.8 7.2 2.6 0.0 0.0 1.5 3.3 2.1 0.0 1.7 6.4 13.9 1.5 1.2 3.0 12.6 6.7 1.1 0.1 0.8 0.0 25.1 19.6 0.7 0.0 2.9 4.9 0.0 1.6 1.4 4.1 4.6 1.8 2.6 0.0 5.9 1.8 10.3 1.7 6.6 0.0 0.5 0.2 1.0 0.6 0.4 15.4 1.3 3.0 2.0 0.2 3.1 6.6 1.8 0.8 0.7 1.4 9.8 3.0 0.8 3.4 0.3 2.1 1.6 TEK "CD202b, TIE-2, TIE2, VMCM, VMCM1" ENSG00000120156 "TEK receptor tyrosine kinase" Q02763 9 27109141-27230174 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Glaucoma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 46.3" "Group enriched" "Detected in many" 10 "Adipocytes: 70.8;Endothelial cells: 73.9;Hepatic stellate cells: 122.0;Microglial cells: 38.4;Oligodendrocyte precursor cells: 137.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HUVEC TERT2: 90.9;NTERA-2: 45.2;TIME: 99.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010359, HPA073265" Approved Supported "Plasma membrane,Centriolar satellite" "Secreted to blood" NA NA 7750000 13000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Centriolar satellite" "CAB010359: AB_2203226, HPA073265: AB_2686592" "unprognostic (2.24e-1)" "unprognostic (1.74e-1)" "unprognostic (5.55e-2)" "unprognostic (1.83e-2)" "unprognostic (1.68e-1)" "unprognostic (1.26e-3)" "prognostic favorable (2.31e-5)" "unprognostic (7.48e-2)" "unprognostic (1.72e-2)" "unprognostic (1.41e-1)" "unprognostic (5.58e-2)" "unprognostic (2.72e-1)" "prognostic favorable (7.81e-4)" "unprognostic (7.50e-3)" "unprognostic (6.87e-3)" "unprognostic (1.83e-1)" "unprognostic (5.24e-3)" 20.1 9.1 8.1 5.8 7.0 0.2 14.0 6.1 8.4 9.3 4.3 5.0 3.7 12.4 2.3 5.3 6.7 11.2 16.8 7.1 6.8 23.0 10.5 28.8 3.7 7.2 6.6 3.5 3.5 4.4 3.0 46.3 7.6 3.8 5.4 0.7 3.1 6.2 10.5 2.8 5.5 12.7 6.8 28.8 4.0 1.4 9.4 1.8 9.1 22.9 2.8 6.9 3.9 6.8 0.3 0.0 3.5 0.0 0.4 5.6 0.1 3.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 2.4 0.0 1.6 0.0 0.0 1.8 0.0 2.2 0.8 0.1 90.9 0.0 0.0 0.0 0.7 0.0 0.0 0.0 45.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 18.3 0.0 0.0 99.1 0.0 0.5 9.1 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 8.1 7.0 6.1 8.4 7.1 6.8 7.2 6.6 7.6 6.8 9.4 6.8 70.8 3.2 1.3 1.3 0.4 1.5 0.0 0.0 0.0 0.0 0.3 0.5 8.6 0.0 0.6 1.8 0.0 0.4 0.4 0.0 0.0 0.0 0.6 0.6 0.8 73.9 0.0 2.7 4.3 0.0 2.8 4.2 0.0 0.7 0.0 0.3 122.0 1.3 0.3 0.0 5.0 0.0 0.0 6.7 2.2 0.9 0.6 0.4 0.0 38.4 0.0 0.1 0.0 137.7 2.1 1.3 0.0 0.4 0.0 0.2 0.0 0.1 0.0 0.2 0.0 1.6 1.9 0.1 0.4 0.3 1.3 1.4 0.5 1.8 0.0 0.0 TENT5C "FAM46C, FLJ20202" ENSG00000183508 "Terminal nucleotidyltransferase 5C" Q5VWP2 1 117606048-117628389 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Host-virus interaction" "Nucleotidyltransferase, RNA-binding, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 89.1" "Cell type enhanced" "Detected in some" "B-cells: 41.8;Breast glandular cells: 34.0;Breast myoepithelial cells: 43.2;dendritic cells: 104.5;Plasma cells: 47.7;T-cells: 48.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 29.3" "Group enriched" "Detected in many" 17 "B-cells: 13.3;granulocytes: 29.3;T-cells: 13.7" "Cell line enhanced" "Detected in many" "Karpas-707: 296.2;RPMI-8226: 185.5;U-266/70: 81.7;U-266/84: 72.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA054049 Uncertain Supported Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 2: Karpas-707 - Immune response" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA054049: AB_2682356" "unprognostic (3.76e-2)" "unprognostic (3.85e-3)" "unprognostic (3.24e-3)" "prognostic favorable (3.75e-5)" "unprognostic (1.17e-1)" "unprognostic (1.55e-3)" "unprognostic (3.29e-1)" "unprognostic (2.88e-2)" "unprognostic (5.75e-2)" "unprognostic (1.36e-3)" "unprognostic (9.41e-3)" "unprognostic (3.91e-2)" "prognostic favorable (2.77e-5)" "unprognostic (6.26e-2)" "unprognostic (3.16e-2)" "unprognostic (3.08e-2)" "unprognostic (1.10e-2)" 2.8 2.4 0.9 17.0 1.0 89.1 11.6 1.1 1.6 10.9 27.4 23.8 16.0 3.2 19.1 3.6 4.8 7.8 6.9 1.4 0.9 7.5 10.3 10.5 18.8 1.6 1.6 9.0 46.8 11.2 2.6 3.8 1.1 6.6 24.8 0.1 25.8 4.1 29.4 1.2 13.0 2.9 1.9 21.7 30.2 43.5 1.0 6.2 14.3 10.9 37.3 14.1 1.9 1.3 0.2 0.1 0.1 1.3 0.1 0.0 1.3 0.6 26.9 0.5 0.2 1.7 0.2 4.9 0.3 0.8 0.3 0.3 0.1 0.5 0.2 17.6 1.6 37.9 0.2 0.0 0.1 22.4 46.8 0.0 0.1 0.4 0.0 0.1 0.1 10.0 5.2 296.2 0.0 3.8 0.1 22.8 3.8 4.5 2.4 0.1 0.1 185.5 0.3 3.7 2.2 0.2 1.7 2.4 1.8 0.6 1.9 0.2 0.5 0.3 2.1 0.1 0.4 81.7 72.8 1.9 1.7 8.1 2.4 29.3 0.0 15.9 3.4 0.0 3.1 13.3 3.3 4.4 0.1 10.4 0.4 1.9 1.6 1.1 0.0 0.3 13.7 2.9 0.9 1.0 1.1 1.6 1.4 0.9 1.6 1.6 1.1 1.9 1.0 1.3 17.0 0.0 0.0 0.0 41.8 0.0 0.0 0.0 0.0 0.0 34.0 43.2 0.0 0.0 0.0 1.8 0.0 1.9 104.5 0.0 11.7 0.8 0.0 8.3 5.4 2.9 0.0 0.0 0.0 5.2 2.2 3.2 0.0 13.7 0.0 0.7 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 47.7 0.0 0.0 9.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 2.2 48.4 1.0 0.0 0.0 TESK1 ENSG00000107140 "Testis associated actin remodelling kinase 1" Q15569 9 35605262-35610041 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 41: Macrophages - Immune response" "unprognostic (5.17e-2)" "unprognostic (2.82e-1)" "unprognostic (4.96e-3)" "unprognostic (5.18e-2)" "unprognostic (2.04e-2)" "unprognostic (8.76e-2)" "prognostic unfavorable (9.68e-4)" "unprognostic (1.82e-2)" "unprognostic (1.24e-1)" "unprognostic (2.66e-3)" "unprognostic (1.22e-2)" "unprognostic (2.56e-1)" "unprognostic (5.57e-2)" "unprognostic (1.74e-2)" "unprognostic (2.34e-1)" "unprognostic (1.43e-2)" "unprognostic (1.25e-3)" 40.2 44.7 24.4 11.2 22.0 6.1 33.5 17.9 25.9 22.6 14.8 29.9 13.3 25.7 11.1 12.8 18.7 13.0 19.2 22.0 21.3 18.0 13.8 19.9 11.9 20.6 24.2 15.9 16.0 16.8 26.6 9.1 21.8 22.4 8.5 6.7 17.4 19.8 69.2 19.1 18.9 17.1 18.2 16.2 22.2 57.0 28.1 10.4 19.0 27.6 8.5 27.9 16.0 20.4 17.0 16.0 10.7 16.9 42.5 17.5 12.1 19.7 17.3 17.8 11.3 9.3 4.8 30.9 10.3 19.7 47.1 5.8 6.8 14.1 3.4 20.0 9.2 4.6 14.1 8.4 24.4 4.0 14.6 17.2 21.8 13.9 19.0 18.9 12.6 15.3 5.3 11.3 18.0 19.1 7.9 18.4 6.2 16.1 18.6 12.9 6.6 7.3 13.1 8.0 8.8 10.3 11.2 13.0 8.1 7.3 15.9 5.7 11.1 39.2 16.2 27.9 12.0 6.0 10.2 11.2 28.2 4.6 9.1 0.0 0.6 0.1 1.1 0.1 1.0 0.3 0.4 1.8 0.8 0.2 0.5 0.5 0.0 0.9 0.3 0.8 0.1 0.7 24.4 22.0 17.9 25.9 22.0 21.3 20.6 24.2 21.8 18.2 28.1 20.4 13.4 6.4 7.7 9.1 8.9 14.4 6.3 5.9 4.6 10.9 13.9 11.0 1.9 7.2 4.2 7.3 8.4 3.8 20.0 19.9 1.9 6.6 35.1 5.6 9.2 9.7 9.5 1.7 6.5 10.4 8.6 9.0 18.8 11.2 1.3 10.1 10.8 8.4 13.9 13.5 8.5 14.8 0.0 7.8 22.4 34.9 12.2 19.3 14.2 2.8 6.3 12.6 20.6 4.5 6.8 10.2 11.0 14.3 10.7 19.2 13.4 7.8 4.2 15.3 6.6 10.1 10.9 14.8 10.0 4.7 13.9 3.3 11.8 5.4 7.3 9.7 TESMIN "CXCDC2, MTL5" ENSG00000132749 "Testis expressed metallothionein like protein" Q9Y4I5 11 68707440-68751520 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "testis: 52.5" "Cell type enhanced" "Detected in some" "Breast glandular cells: 9.6;Breast myoepithelial cells: 7.4;Endometrial ciliated cells: 31.5;Glandular and luminal cells: 27.0;Proximal tubular cells: 11.5" "Cancer enhanced" "Detected in many" "breast cancer: 6.8" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HMC-1: 11.9;T-47d: 23.8" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA018539 Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 6: T47d - Mammary gland" "Cluster 44: Endometrium - Transcription" Nucleoplasm "Vesicles, Cytosol" "HPA018539: " "unprognostic (1.99e-1)" "unprognostic (3.97e-3)" "unprognostic (1.34e-2)" "prognostic unfavorable (1.75e-5)" "unprognostic (3.22e-2)" "unprognostic (6.71e-2)" "unprognostic (1.76e-2)" "unprognostic (6.99e-3)" "unprognostic (2.54e-1)" "unprognostic (5.33e-2)" "unprognostic (2.19e-2)" "unprognostic (8.47e-2)" "unprognostic (5.27e-2)" "unprognostic (6.39e-2)" "unprognostic (2.99e-1)" "unprognostic (9.85e-2)" "unprognostic (3.17e-1)" 0.3 0.5 0.7 1.0 0.7 7.4 4.3 0.6 0.6 0.7 0.6 2.5 1.4 0.7 0.7 1.6 1.7 0.4 0.2 0.5 0.8 3.1 0.4 0.4 1.3 1.2 0.7 0.8 1.1 2.1 2.3 0.3 1.2 2.3 2.9 1.5 1.9 1.1 0.0 0.6 1.4 0.4 0.5 1.3 0.9 52.5 0.7 2.1 1.1 0.1 1.1 0.4 0.9 0.5 7.2 3.1 1.3 0.1 0.0 0.0 3.5 1.6 0.8 2.2 1.0 0.9 7.1 2.9 1.6 0.3 0.0 3.4 1.0 1.4 1.7 3.0 2.5 2.1 1.0 0.0 0.0 1.5 11.9 0.0 3.8 0.1 2.2 3.0 0.7 3.4 4.5 5.4 0.3 4.8 0.8 4.2 7.3 3.3 3.1 1.9 0.4 0.8 2.6 0.1 4.4 4.7 0.0 1.5 0.0 3.7 23.8 10.0 2.7 0.2 0.5 0.2 0.1 2.1 2.0 2.8 0.1 4.2 1.9 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.1 0.1 0.7 0.7 0.6 0.6 0.5 0.8 1.2 0.7 1.2 0.5 0.7 0.5 0.7 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 9.6 7.4 0.0 0.0 0.6 0.0 0.0 1.8 0.7 0.0 5.9 6.3 0.0 31.5 2.6 0.3 0.0 0.0 0.0 4.0 4.7 0.3 0.0 27.0 2.5 4.2 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.6 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.5 0.0 0.0 11.5 1.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.8 1.1 0.2 0.0 0.0 TET1 "bA119F7.1, CXXC6, KIAA1676, LCX" ENSG00000138336 "Tet methylcytosine dioxygenase 1" Q8NFU7 10 68560337-68694487 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Dioxygenase, DNA-binding, Oxidoreductase, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.9" "Cell type enhanced" "Detected in many" "Astrocytes: 54.5;Extravillous trophoblasts: 79.9;Oligodendrocyte precursor cells: 44.7;Oligodendrocytes: 45.3;Theca cells: 43.7" "Cancer enriched" "Detected in some" 15 "testis cancer: 10.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 17.7;HAP1: 20.4;K-562: 12.0;NTERA-2: 11.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019032, HPA057273" Supported "Nucleoplasm,Nuclear membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 1: K-562 - Erythropoiesis" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "Nuclear membrane" "HPA019032: AB_1847363, HPA057273: AB_2683391" "unprognostic (1.60e-1)" "unprognostic (8.30e-2)" "unprognostic (9.85e-2)" "unprognostic (1.67e-2)" "unprognostic (1.27e-1)" "unprognostic (8.15e-2)" "unprognostic (3.60e-3)" "unprognostic (1.12e-1)" "unprognostic (2.00e-1)" "unprognostic (7.90e-3)" "unprognostic (1.83e-1)" "unprognostic (1.71e-1)" "unprognostic (1.18e-3)" "unprognostic (2.88e-4)" "unprognostic (4.02e-2)" "unprognostic (2.54e-1)" "unprognostic (9.52e-3)" 0.4 0.2 0.6 0.2 1.2 0.3 0.4 4.9 0.7 0.7 0.8 0.4 0.1 0.9 0.6 0.2 0.5 0.3 0.3 0.3 0.9 0.3 0.2 0.2 0.3 0.9 1.3 0.8 0.2 0.7 0.3 1.2 1.1 0.6 0.3 1.5 1.0 0.3 0.9 0.3 0.2 0.5 1.0 0.3 0.4 0.2 1.1 2.0 0.5 0.3 0.3 0.2 0.4 2.2 0.7 0.8 8.0 9.0 0.8 0.7 17.7 0.4 1.0 0.7 1.2 5.5 0.3 0.0 0.3 0.8 0.1 0.0 20.4 0.0 0.8 0.3 3.3 2.1 0.0 4.9 1.2 1.9 1.0 1.0 0.1 0.5 0.1 1.6 0.1 3.5 12.0 1.4 0.7 0.6 3.3 1.4 11.9 0.0 1.1 3.2 2.5 0.2 0.4 0.8 2.2 3.5 0.4 0.5 1.6 7.9 1.0 1.5 0.3 0.7 1.6 0.0 0.6 0.5 0.6 3.2 0.2 0.0 0.2 0.0 0.0 0.2 0.3 0.0 0.4 0.3 0.1 0.2 0.0 0.1 0.2 0.2 0.0 0.1 0.0 0.2 0.5 0.0 0.6 1.2 4.9 0.7 0.3 0.9 0.9 1.3 1.1 1.0 1.1 2.2 6.3 3.2 6.2 54.5 2.5 1.1 1.8 0.4 5.2 2.5 7.0 9.5 7.2 1.5 2.6 0.0 10.4 21.0 3.0 0.2 0.0 2.7 0.8 3.6 34.2 4.8 13.8 2.5 15.6 0.4 79.9 15.4 1.5 2.9 0.0 13.6 5.7 2.5 3.9 35.3 20.6 0.3 4.1 0.0 0.3 1.7 25.7 0.8 1.8 12.2 0.4 16.1 5.2 44.7 45.3 0.6 0.0 20.7 7.3 1.4 0.0 0.9 0.8 12.5 6.6 21.9 10.7 0.5 1.5 0.8 1.1 27.9 2.6 43.7 0.6 0.4 TEX11 "MZIP4, Spo22, TGC1, TSGA3, ZIP4" ENSG00000120498 "Testis expressed 11" Q8IYF3 X 70528940-70908711 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Meiosis "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "pancreas: 58.8" "Cell type enhanced" "Detected in some" "Distal enterocytes: 20.1;Early spermatids: 14.7;Exocrine glandular cells: 9.7;Late spermatids: 28.0;Paneth cells: 12.5;Spermatocytes: 46.5;Spermatogonia: 30.0" "Cancer enhanced" "Detected in some" "renal cancer: 1.3;testis cancer: 1.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA002950 Approved NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 25: Pancreas - Digestion" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA002950: AB_1080249" "unprognostic (6.78e-3)" "unprognostic (3.57e-3)" "unprognostic (2.87e-3)" "unprognostic (7.77e-2)" "unprognostic (7.75e-3)" "unprognostic (2.14e-2)" "unprognostic (1.66e-1)" "unprognostic (1.28e-1)" "unprognostic (1.74e-1)" "unprognostic (8.30e-2)" "unprognostic (5.74e-3)" "unprognostic (2.88e-1)" "unprognostic (1.11e-2)" "unprognostic (1.53e-1)" "unprognostic (3.03e-1)" "unprognostic (3.48e-1)" "unprognostic (1.56e-2)" 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 3.9 1.4 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.4 0.0 58.8 0.0 0.0 0.2 0.0 0.1 1.5 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.9 0.5 11.6 0.0 0.1 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.5 0.0 0.0 0.0 0.0 0.0 20.1 0.0 0.0 14.7 0.1 0.0 0.2 1.2 0.0 2.6 9.7 0.0 1.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 2.2 0.8 0.0 0.0 0.3 28.0 0.6 0.1 0.0 0.0 0.6 0.0 0.0 2.0 1.9 0.5 12.5 0.7 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 46.5 30.0 0.0 0.1 0.0 0.0 0.1 1.5 0.0 TEX13A ENSG00000268629 "Testis expressed 13A" Q9BXU3 X 105218929-105220694 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 107 "testis: 10.6" "Group enriched" "Detected in some" 37 "Early spermatids: 90.8;Late spermatids: 159.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA072257 Enhanced NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 34: Spermatids - Unknown function" "HPA072257: AB_2732198" "unprognostic (3.70e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 90.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 159.4 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TEX14 CT113 ENSG00000121101 "Testis expressed 14, intercellular bridge forming factor" Q8IWB6 17 58556678-58692055 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "testis: 27.0" "Group enriched" "Detected in many" 4 "Early spermatids: 23.3;Spermatocytes: 56.4;Spermatogonia: 16.2" "Cancer enhanced" "Detected in some" "breast cancer: 0.9" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 6.3;Karpas-707: 7.9;MCF7: 3.3" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA030620, HPA077020" Enhanced Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Cytosol "Vesicles, Plasma membrane" "HPA030620: AB_10601598, HPA077020: AB_2732327" "unprognostic (1.21e-2)" "unprognostic (2.12e-1)" "unprognostic (2.06e-1)" "unprognostic (9.49e-2)" "unprognostic (2.48e-1)" "unprognostic (1.23e-2)" "unprognostic (1.10e-1)" "unprognostic (6.17e-2)" "unprognostic (2.07e-2)" "unprognostic (1.61e-3)" "unprognostic (2.67e-2)" "unprognostic (8.10e-2)" "unprognostic (1.76e-9)" "unprognostic (1.77e-1)" "unprognostic (2.54e-1)" "unprognostic (5.00e-3)" "unprognostic (5.88e-2)" 0.1 0.1 0.5 0.1 0.6 1.7 0.2 1.1 0.6 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.4 0.5 0.4 0.2 0.2 0.1 0.5 0.5 0.3 0.1 0.0 0.2 0.1 0.5 0.2 0.0 1.1 0.1 0.0 0.0 0.1 0.1 0.0 0.5 0.2 0.1 27.0 0.5 0.0 0.0 0.0 0.1 0.1 0.0 0.8 0.0 0.0 0.1 1.7 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.5 0.1 0.0 0.1 0.0 0.2 0.0 0.1 6.3 0.9 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.3 0.1 7.9 0.0 3.3 0.3 0.0 0.4 0.1 0.1 0.3 0.2 1.2 0.0 0.1 0.9 0.1 0.0 0.0 0.4 0.3 0.3 0.0 0.0 0.0 0.2 0.0 0.0 1.4 0.3 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 1.1 0.6 0.4 0.5 0.5 0.5 0.5 0.5 0.5 0.8 4.4 0.0 0.0 2.9 5.7 0.9 1.8 0.7 2.8 0.6 4.7 7.2 1.3 5.7 1.5 1.8 0.0 1.6 0.7 0.1 0.0 0.0 23.3 0.4 0.2 1.5 0.0 0.0 2.2 0.0 1.0 0.7 0.5 1.8 1.3 0.2 1.4 0.8 3.7 0.0 2.2 0.5 2.0 0.6 2.3 6.4 0.3 4.6 3.6 2.8 0.0 0.6 1.0 1.0 3.0 0.1 0.0 0.4 4.3 0.7 0.0 0.1 0.2 1.3 0.0 1.2 1.5 56.4 16.2 1.7 0.1 1.1 0.7 0.0 0.0 0.4 TEX22 ENSG00000226174 "Testis expressed 22" C9J3V5 14 105398538-105450106 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 5.0" "Group enriched" "Detected in some" 8 "Early spermatids: 290.6;Late spermatids: 614.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 3.2;U-266/70: 2.3;U-937: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA065576 Enhanced NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 31: Spermatids - Spermatogenesis" "HPA065576: AB_2685513" "unprognostic (3.99e-2)" "unprognostic (6.00e-2)" "unprognostic (1.30e-3)" "unprognostic (2.06e-1)" "unprognostic (3.36e-1)" "unprognostic (1.62e-2)" "unprognostic (7.48e-2)" "unprognostic (1.52e-2)" "unprognostic (3.95e-2)" "unprognostic (1.53e-5)" "unprognostic (1.42e-4)" "unprognostic (8.13e-2)" "unprognostic (5.96e-2)" "unprognostic (2.18e-2)" "unprognostic (5.25e-2)" "unprognostic (1.68e-2)" "unprognostic (5.91e-3)" 0.2 0.0 0.7 0.2 0.8 0.4 0.3 1.1 0.7 0.3 0.3 0.1 0.1 0.1 0.0 0.1 0.5 0.1 0.1 0.6 0.5 0.6 0.1 0.1 0.5 0.9 0.8 0.6 0.3 0.2 0.1 0.1 0.8 0.4 0.0 0.1 0.2 0.1 0.1 0.2 0.4 0.0 0.7 0.7 0.2 5.0 0.7 1.0 0.3 0.0 0.2 0.1 0.2 1.2 0.2 0.3 0.3 1.4 0.4 0.0 0.3 0.1 0.0 0.0 0.2 0.1 0.2 0.8 0.1 0.0 0.0 0.2 0.2 0.0 0.0 3.2 0.2 0.1 0.5 0.0 0.1 0.2 0.8 0.2 0.1 0.0 0.0 0.3 0.0 0.3 0.0 0.9 0.0 1.0 0.1 0.1 0.1 0.0 0.1 0.8 0.0 0.0 0.1 0.2 0.2 0.3 0.0 0.0 0.1 0.2 0.2 0.3 0.0 0.1 0.1 0.3 0.0 2.3 0.3 0.3 0.1 1.7 1.2 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.7 0.8 1.1 0.7 0.6 0.5 0.9 0.8 0.8 0.7 0.7 1.2 0.3 0.0 0.0 6.2 1.1 0.4 0.4 0.2 0.6 0.1 1.0 0.9 0.4 0.0 0.1 0.0 0.0 0.2 0.3 0.2 1.9 0.6 290.6 1.3 0.5 0.4 0.0 0.8 3.2 0.6 0.1 0.4 0.0 0.4 4.5 2.2 0.0 0.1 1.0 0.0 4.8 0.2 0.0 1.9 0.3 614.3 4.1 1.0 1.8 1.0 1.2 0.3 0.0 6.6 5.8 0.6 0.1 2.2 0.3 0.5 0.8 0.5 0.4 0.2 6.6 0.9 0.6 54.2 3.0 0.4 0.1 0.1 0.6 0.4 0.2 0.2 TEX38 "ATPAF1-AS1, C1orf223, LOC374973, THEG4" ENSG00000186118 "Testis expressed 38" Q6PEX7 1 46668855-46673594 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 416 "testis: 388.6" "Group enriched" "Detected in some" 52 "Early spermatids: 2382.9;Late spermatids: 5035.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA073711 Approved Vesicles NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 74: Testis - Spermatogenesis" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "HPA073711: " "unprognostic (8.46e-2)" "unprognostic (1.99e-1)" "unprognostic (3.14e-2)" "unprognostic (8.86e-2)" "unprognostic (6.81e-3)" "unprognostic (3.50e-1)" "unprognostic (1.99e-1)" "unprognostic (9.21e-2)" "unprognostic (5.39e-2)" "unprognostic (4.15e-3)" "unprognostic (4.93e-4)" "unprognostic (2.64e-1)" "unprognostic (5.28e-2)" "unprognostic (2.84e-2)" "unprognostic (7.96e-2)" "unprognostic (7.84e-2)" "unprognostic (3.48e-1)" 0.2 0.2 0.2 0.0 0.3 0.1 0.4 0.3 0.4 0.1 0.0 0.1 0.0 0.2 0.9 0.1 0.1 0.1 0.1 0.2 0.3 0.3 0.2 0.1 0.0 0.1 0.1 0.1 0.2 0.6 0.8 0.2 0.1 0.5 0.1 0.2 0.2 0.2 0.1 0.2 0.1 0.1 0.1 0.0 0.2 388.6 0.2 0.1 0.4 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.4 0.3 0.2 0.4 0.0 0.3 0.1 0.0 0.5 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.3 0.1 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.3 0.3 0.4 0.2 0.3 0.1 0.1 0.1 0.1 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2382.9 0.2 0.1 1.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5035.0 28.3 1.5 0.0 1.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 18.4 0.1 0.0 0.0 0.0 0.0 0.3 6.6 0.1 0.0 71.0 14.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 TEX45 "C19orf45, FLJ35784" ENSG00000198723 "Testis expressed 45" Q8NA69 19 7492976-7508450 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "testis: 20.6" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 1.0;Exocrine glandular cells: 1.1;Glandular and luminal cells: 3.0;Granulosa cells: 1.4;Pancreatic endocrine cells: 1.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 44: Endometrium - Transcription" "unprognostic (7.96e-3)" "unprognostic (3.90e-2)" "unprognostic (5.17e-2)" "unprognostic (1.84e-3)" "unprognostic (7.44e-2)" "unprognostic (1.50e-2)" "unprognostic (3.74e-2)" "unprognostic (3.72e-2)" "unprognostic (6.42e-2)" "unprognostic (4.71e-2)" "unprognostic (4.07e-2)" "unprognostic (1.94e-1)" "unprognostic (4.72e-1)" "unprognostic (4.32e-2)" "unprognostic (3.35e-2)" "unprognostic (1.11e-1)" "unprognostic (1.58e-3)" 0.1 0.6 0.3 0.2 0.6 1.7 0.1 0.2 0.8 0.0 0.0 0.2 0.2 0.3 0.1 0.2 0.2 0.4 0.0 0.4 0.6 0.0 0.1 0.2 0.2 0.5 0.4 0.2 0.2 0.1 1.0 0.2 0.7 0.1 0.2 1.4 0.4 0.0 0.2 1.4 0.8 0.1 0.0 0.1 0.2 20.6 0.5 0.0 0.2 0.0 0.1 0.0 0.0 1.9 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.3 0.2 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.4 0.2 0.0 0.0 0.6 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.3 0.5 0.0 0.5 0.4 0.2 0.0 0.5 0.1 0.0 0.0 0.1 0.1 0.3 0.7 0.1 0.2 0.3 0.0 0.1 0.4 0.5 0.2 0.0 0.1 0.1 0.2 0.3 0.0 0.2 0.2 0.2 0.0 0.6 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.2 0.1 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.3 0.6 0.2 0.8 0.4 0.6 0.5 0.4 0.7 0.0 0.5 1.9 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.0 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.0 3.0 0.0 1.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TEX46 C1orf234 ENSG00000227868 "Testis expressed 46" H3BTG2 1 23010834-23015852 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 55 "testis: 83.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HSkMC: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (3.11e-1)" "unprognostic (1.86e-1)" "unprognostic (9.04e-2)" "unprognostic (2.13e-1)" "unprognostic (1.24e-2)" "unprognostic (6.33e-2)" "unprognostic (2.84e-1)" "unprognostic (1.01e-1)" "unprognostic (1.53e-1)" "unprognostic (9.76e-2)" "unprognostic (8.12e-2)" "unprognostic (3.82e-3)" "unprognostic (2.29e-5)" "unprognostic (1.06e-1)" "unprognostic (1.15e-1)" "unprognostic (7.60e-2)" 0.1 0.1 0.4 0.0 0.7 0.0 0.3 0.3 1.5 0.2 0.0 0.0 0.1 0.2 0.7 0.4 0.2 0.0 0.1 0.5 0.5 0.1 0.1 0.2 0.0 0.6 0.6 0.1 0.2 0.1 0.2 0.0 0.5 0.2 0.0 0.7 0.0 0.0 0.1 0.7 0.0 0.0 0.3 0.0 0.0 83.2 0.7 0.0 0.0 0.0 0.2 0.0 0.1 1.0 0.1 0.0 0.4 0.1 0.9 0.2 0.4 0.0 0.1 0.3 0.2 0.0 0.2 0.1 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.7 0.0 0.4 0.0 0.0 0.0 0.1 1.1 0.3 0.1 0.2 0.0 0.2 0.6 0.2 0.1 0.2 0.3 0.0 0.2 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.4 0.1 0.0 0.0 0.4 0.0 0.4 0.1 0.1 0.1 0.0 0.7 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.7 0.3 1.5 0.5 0.5 0.6 0.6 0.5 0.3 0.7 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 TEX48 ENSG00000230601 "Testis expressed 48" A0A1B0GUV7 9 114666434-114682192 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 36 "testis: 26.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "Karpas-707: 5.8" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 74: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "unprognostic (2.70e-1)" "unprognostic (6.41e-2)" "unprognostic (7.83e-2)" "unprognostic (2.53e-1)" "unprognostic (5.10e-2)" "unprognostic (2.33e-2)" "unprognostic (1.70e-1)" "unprognostic (5.11e-2)" "unprognostic (1.51e-1)" "unprognostic (4.46e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.4 0.0 0.1 1.4 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 5.8 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.7 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TEX49 LINC00935 ENSG00000257987 "Testis expressed 49" A0A1B0GTD5 12 48727435-48765790 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "testis: 20.8" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "stomach cancer: 0.6;testis cancer: 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA066635 Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 36: Testis - Spermatogenesis" Nucleoplasm "Nuclear bodies" "HPA066635: " "unprognostic (2.63e-2)" "unprognostic (6.32e-3)" "unprognostic (8.28e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 20.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TFCP2L1 "CRTR1, LBP-9" ENSG00000115112 "Transcription factor CP2 like 1" Q9NZI6 2 121216587-121285202 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 49.1;salivary gland: 97.5" "Cell type enhanced" "Detected in many" "Collecting duct cells: 79.1;Distal enterocytes: 117.9;Glandular and luminal cells: 83.0;Ionocytes: 262.4" "Cancer enhanced" "Detected in many" "testis cancer: 21.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 18.2;HEL: 15.7;hTCEpi: 17.3;RPTEC TERT1: 42.4;RT4: 31.8;SCLC-21H: 13.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA029708 Uncertain Approved "Nucleoli fibrillar center,Mitochondria" Yes NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" "Nucleoli fibrillar center" Mitochondria "HPA029708: AB_10602479" "unprognostic (8.85e-3)" "unprognostic (4.19e-1)" "unprognostic (1.06e-1)" "unprognostic (1.02e-2)" "unprognostic (1.48e-1)" "unprognostic (3.91e-2)" "unprognostic (1.32e-2)" "unprognostic (3.16e-1)" "unprognostic (3.25e-2)" "unprognostic (2.72e-3)" "unprognostic (1.20e-3)" "unprognostic (5.76e-2)" "prognostic favorable (7.72e-6)" "unprognostic (1.05e-1)" "unprognostic (2.39e-1)" "unprognostic (6.67e-3)" "unprognostic (2.01e-1)" 1.9 0.3 0.9 1.7 1.6 0.2 28.7 1.7 1.1 18.1 19.0 19.0 0.6 0.5 8.3 13.3 3.5 2.9 0.2 1.7 0.9 49.1 0.2 5.6 0.2 1.6 2.1 0.1 6.4 2.6 0.8 7.4 1.1 13.6 22.6 0.0 97.5 2.0 2.6 31.9 3.2 0.6 0.7 1.8 16.3 1.1 1.9 0.2 37.6 0.1 1.2 1.8 10.9 0.7 0.0 1.6 0.0 0.1 0.0 0.0 18.2 0.0 0.0 0.0 0.0 1.5 1.1 0.0 0.7 0.0 0.7 0.4 4.4 4.5 0.0 0.0 3.2 15.7 0.0 0.0 0.0 0.0 0.6 0.0 17.3 0.0 4.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 7.9 0.1 0.0 0.5 2.1 42.4 31.8 13.3 0.1 1.7 0.1 0.0 6.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.6 1.7 1.1 1.7 0.9 1.6 2.1 1.1 0.7 1.9 0.7 0.1 6.4 28.8 3.9 0.3 1.7 38.0 10.3 28.5 0.0 22.1 11.6 2.6 17.2 35.4 79.1 0.0 32.2 0.9 117.9 31.3 2.7 0.1 43.5 5.8 1.0 10.2 0.0 0.2 1.5 2.3 0.8 58.6 83.0 0.0 1.2 0.0 0.4 4.9 0.0 0.3 31.2 262.4 4.6 0.8 0.5 0.3 5.5 7.2 9.4 0.2 0.5 0.0 0.0 0.1 7.4 28.0 0.0 2.1 36.3 0.3 27.7 11.9 0.0 0.0 1.9 1.1 0.1 1.5 41.0 3.3 20.2 1.1 9.5 44.3 40.7 TFDP3 "CT30, E2F-like, HCA661" ENSG00000183434 "Transcription factor Dp family member 3" Q5H9I0 X 133216662-133218354 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 35 "testis: 4.2" "Group enriched" "Detected in some" 17 "Spermatocytes: 23.5;Spermatogonia: 31.1" "Cancer enhanced" "Detected in some" "liver cancer: 0.7;testis cancer: 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA077304 Supported "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Nucleoplasm, Nuclear membrane" Cytosol "HPA077304: " "unprognostic (1.57e-1)" "unprognostic (2.17e-1)" "unprognostic (3.22e-1)" "unprognostic (2.91e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 23.5 31.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TGFBR2 "MFS2, TBR-ii, TBRII" ENSG00000163513 "Transforming growth factor beta receptor 2" P37173 3 30606601-30694142 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Apoptosis, Differentiation, Growth regulation" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Cancer-related genes, Craniosynostosis, Disease variant, FDA approved drug targets, Hereditary nonpolyposis colorectal cancer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 391.5;Endothelial cells: 236.4;Hepatic stellate cells: 478.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 313.6;ASC TERT1: 472.3;HSkMC: 430.0;LHCN-M2: 381.7;TIME: 418.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB073537 Supported "Plasma membrane" NA NA 810000 "Cluster 5: Granulocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "CAB073537: " "unprognostic (1.74e-1)" "unprognostic (1.84e-2)" "unprognostic (3.70e-1)" "unprognostic (3.02e-2)" "unprognostic (1.92e-1)" "unprognostic (2.26e-1)" "unprognostic (1.96e-1)" "unprognostic (1.62e-1)" "unprognostic (1.40e-1)" "unprognostic (2.24e-2)" "unprognostic (7.36e-2)" "unprognostic (1.12e-1)" "unprognostic (1.65e-2)" "unprognostic (4.72e-2)" "unprognostic (1.81e-2)" "unprognostic (8.81e-2)" "unprognostic (8.02e-2)" 230.0 56.1 16.5 73.8 12.9 29.4 145.7 13.8 19.3 90.0 30.6 96.0 44.2 69.1 18.2 44.9 69.6 91.9 95.2 10.6 13.4 67.9 59.1 148.0 70.1 17.6 16.5 26.6 52.0 59.0 16.9 81.6 16.7 44.1 54.1 2.1 49.2 60.8 31.1 39.1 77.7 107.2 17.3 111.1 63.4 7.8 21.5 49.7 91.8 62.2 60.7 98.0 55.1 17.2 16.6 100.2 5.3 0.1 313.6 472.3 15.9 83.9 116.1 28.5 27.7 22.9 86.6 2.2 298.2 117.2 32.2 33.3 4.0 125.4 42.0 7.0 8.9 10.1 10.7 104.5 128.5 14.9 76.6 430.0 93.6 126.3 114.4 117.0 296.0 10.9 1.8 0.0 381.7 1.3 16.2 10.5 2.2 75.7 39.8 14.1 36.4 2.1 113.5 40.5 0.1 5.6 24.9 6.1 22.0 6.6 0.0 14.0 418.6 134.7 33.2 61.4 32.0 2.8 0.3 12.5 80.1 16.1 55.8 9.0 3.0 11.5 3.4 3.1 3.3 4.5 4.8 3.3 2.6 6.4 16.6 7.3 13.1 1.9 8.0 6.6 0.7 3.8 16.5 12.9 13.8 19.3 10.6 13.4 17.6 16.5 16.7 17.3 21.5 17.2 391.5 144.2 99.7 0.7 77.0 37.3 18.9 23.5 39.9 5.1 23.7 24.1 84.5 50.1 39.5 27.6 0.0 6.8 85.3 10.5 3.9 13.1 2.5 28.3 57.5 236.4 8.4 20.4 0.4 15.8 5.1 129.2 39.3 30.8 29.8 0.7 478.0 55.5 30.4 0.0 1.0 12.4 22.4 147.0 58.0 3.8 32.9 67.9 30.2 170.5 47.5 0.2 56.7 6.0 2.4 37.6 12.1 47.4 37.5 8.6 13.6 7.2 14.7 1.2 32.9 60.8 53.4 0.3 1.2 8.0 30.5 3.7 68.2 1.7 14.5 10.8 TGIF1 "HPE4, TGIF" ENSG00000177426 "TGFB induced factor homeobox 1" Q15583 18 3411608-3459978 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Disease variant, Holoprosencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 783.4;Basal respiratory cells: 419.8;Basal squamous epithelial cells: 483.2;Urothelial cells: 426.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA062160 Supported Nucleoplasm NA Yes "Cluster 44: Non-specific - Transcription" "Cluster 68: Epididymis - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "HPA062160: AB_2684701" "unprognostic (1.11e-2)" "unprognostic (5.20e-2)" "unprognostic (2.40e-1)" "unprognostic (1.97e-1)" "unprognostic (3.57e-3)" "unprognostic (3.10e-2)" "unprognostic (2.75e-1)" "unprognostic (4.34e-2)" "unprognostic (1.94e-2)" "unprognostic (1.96e-3)" "prognostic unfavorable (6.47e-4)" "unprognostic (9.60e-2)" "unprognostic (1.12e-2)" "unprognostic (9.81e-2)" "unprognostic (4.60e-1)" "unprognostic (7.07e-2)" "unprognostic (2.48e-3)" 51.2 40.1 21.7 43.3 20.8 41.5 57.6 22.4 25.7 68.9 30.2 51.5 31.6 51.2 133.7 46.7 74.7 65.3 29.8 20.2 29.3 74.0 61.5 47.6 26.4 29.8 27.3 67.3 46.9 26.9 22.0 63.8 25.7 54.6 65.7 8.0 56.5 56.1 34.4 60.2 37.8 37.4 27.5 35.5 49.1 25.9 25.7 40.0 66.7 26.9 27.0 112.1 40.0 28.4 33.6 148.5 92.7 29.3 90.0 121.7 235.7 63.1 236.6 49.9 62.1 61.0 142.6 1.9 20.9 49.8 165.7 33.7 35.0 73.8 61.6 13.9 16.8 4.3 73.2 110.5 178.8 47.6 38.3 89.5 291.7 89.7 233.7 131.3 104.4 22.3 36.0 0.4 95.6 65.8 31.1 58.8 240.8 119.0 34.8 32.8 43.2 10.3 198.1 156.7 27.1 26.5 166.2 123.0 92.5 151.3 28.1 43.7 49.6 77.5 65.6 92.7 41.1 5.0 0.6 15.7 78.5 18.6 98.2 65.4 42.8 7.6 62.9 16.6 67.8 46.5 52.5 61.9 35.1 32.2 37.1 43.5 19.8 21.5 16.7 3.3 32.1 36.3 21.7 20.8 22.4 25.7 20.2 29.3 29.8 27.3 25.7 27.5 25.7 28.4 41.0 35.3 40.2 8.1 106.5 359.6 783.4 419.8 483.2 0.0 114.1 72.1 5.6 100.1 128.3 123.2 0.0 161.6 60.1 30.0 49.0 117.1 41.5 167.2 58.5 66.6 46.4 25.7 2.7 75.0 220.9 102.8 79.0 240.2 68.0 71.5 29.3 35.7 71.8 1.7 0.6 99.4 136.3 44.9 221.1 9.7 28.6 126.8 76.5 7.5 71.9 6.7 11.3 4.0 1.7 106.0 53.0 15.4 15.1 308.1 24.9 113.1 93.3 0.1 32.9 90.9 86.6 7.9 15.4 223.9 257.1 150.4 103.7 8.0 91.8 426.2 TGM7 TGMZ ENSG00000159495 "Transglutaminase 7" Q96PF1 15 43276271-43302255 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 1.6" "Group enriched" "Detected in some" 11 "Early spermatids: 62.0;Late spermatids: 16.7" "Cancer enriched" "Detected in single" 13 "endometrial cancer: 2.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 35 "EFO-21: 3.5" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 16: Immune cells - Immune response" "Cluster 38: EFO-21 - Unknown function" "Cluster 29: Early spermatids - Spermatogenesis" "unprognostic (2.45e-2)" "unprognostic (2.04e-1)" "unprognostic (2.82e-2)" "unprognostic (1.71e-2)" "unprognostic (1.07e-1)" "unprognostic (2.01e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.4 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 62.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 16.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.8 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 3.5 THAP10 ENSG00000129028 "THAP domain containing 10" Q9P2Z0 15 70881342-70892433 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 17.5;Early spermatids: 12.6;Spermatocytes: 19.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "non-classical monocyte: 4.2" "Lineage enriched" "Detected in single" 7 "monocytes: 4.2" "Cell line enhanced" "Detected in many" "U-2197: 40.4" "HPA041416, HPA073220" Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 18: U-2197 - ECM organization" "Cluster 56: Bipolar cells - Visual perception" Nucleoplasm "Golgi apparatus, Cytosol" "HPA041416: AB_10795592, HPA073220: " "unprognostic (1.00e-1)" "unprognostic (3.51e-1)" "unprognostic (5.42e-2)" "unprognostic (2.43e-2)" "unprognostic (1.34e-1)" "unprognostic (6.15e-2)" "unprognostic (6.25e-2)" "unprognostic (2.16e-2)" "unprognostic (2.99e-2)" "unprognostic (6.47e-2)" "unprognostic (1.55e-3)" "unprognostic (3.71e-2)" "prognostic favorable (3.05e-5)" "unprognostic (1.25e-2)" "unprognostic (2.12e-2)" "unprognostic (7.46e-2)" "unprognostic (9.44e-3)" 1.7 2.2 4.6 1.3 5.2 0.1 1.9 6.1 7.3 2.4 2.4 2.2 2.3 2.1 1.8 1.9 3.2 1.5 4.7 3.9 5.2 3.0 2.1 1.8 1.0 5.1 5.4 3.7 1.9 5.1 1.7 1.8 5.2 3.0 1.9 10.8 1.8 3.1 2.3 1.3 1.2 2.0 5.0 0.9 2.9 3.4 6.3 0.9 3.6 2.3 0.9 2.6 1.4 5.9 7.3 12.6 7.7 9.8 4.1 5.0 0.1 13.5 6.1 11.4 13.5 2.0 9.5 0.0 8.2 3.8 14.3 11.3 16.2 3.7 10.2 0.0 8.3 2.6 6.2 0.9 2.0 0.7 5.2 1.6 5.1 6.5 6.2 7.9 5.8 0.0 0.9 0.0 8.3 5.7 0.0 2.9 11.2 5.2 5.3 0.0 9.9 0.3 5.1 5.9 8.6 8.9 9.3 3.9 6.5 7.5 4.6 6.3 4.3 7.9 5.6 40.4 9.6 3.4 4.3 0.0 5.0 0.9 11.6 0.0 0.3 0.0 0.0 0.5 0.0 0.3 0.2 0.0 0.6 0.1 0.0 0.1 0.0 0.4 4.2 0.0 0.2 0.1 4.6 5.2 6.1 7.3 3.9 5.2 5.1 5.4 5.2 5.0 6.3 5.9 3.5 0.0 0.5 0.0 0.5 1.8 4.1 2.4 1.2 17.5 2.0 2.0 6.1 1.5 2.0 11.0 0.0 0.2 0.0 2.5 9.8 3.0 12.6 5.5 1.9 2.7 3.0 0.4 3.0 1.1 0.3 2.4 1.1 1.1 0.0 2.1 1.4 1.8 1.3 1.7 4.0 1.5 8.2 0.6 1.0 7.8 2.5 0.7 0.0 0.0 0.1 5.2 0.0 1.0 4.7 0.8 5.3 4.9 1.2 2.2 0.6 6.8 5.4 4.6 0.0 1.5 2.9 19.3 2.7 2.6 1.4 0.1 0.2 1.8 2.9 4.2 THEG "CT56, THEG1" ENSG00000105549 "Theg spermatid protein" Q9P2T0 19 361747-376026 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "testis: 42.4" "Group enriched" "Detected in some" 45 "Early spermatids: 163.2;Late spermatids: 560.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 16 "HDLM-2: 64.4;MCF7: 18.1" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (2.48e-1)" "unprognostic (6.37e-3)" "unprognostic (7.89e-3)" "unprognostic (2.34e-1)" "unprognostic (3.00e-1)" "unprognostic (5.17e-2)" "unprognostic (2.57e-1)" "unprognostic (5.57e-2)" "unprognostic (7.09e-4)" "unprognostic (1.73e-1)" "unprognostic (1.39e-1)" "unprognostic (1.14e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.3 0.5 1.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 2.8 0.1 0.3 0.1 0.0 0.0 42.4 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 64.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.5 0.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 163.2 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 560.0 1.2 0.3 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 2.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 THEMIS2 "C1orf38, ICB-1" ENSG00000130775 "Thymocyte selection associated family member 2" Q5TEJ8 1 27872543-27886685 "Predicted intracellular proteins" "Immunity, Inflammatory response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 215.5;lymphoid tissue: 126.0" "Cell type enhanced" "Detected in many" "dendritic cells: 87.5;Hofbauer cells: 62.6;Kupffer cells: 135.9;Langerhans cells: 59.9;Macrophages: 125.4;monocytes: 144.8;Plasma cells: 57.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 403.3;eosinophil: 341.0;intermediate monocyte: 441.4;myeloid DC: 309.6;neutrophil: 498.1;non-classical monocyte: 454.6;plasmacytoid DC: 125.2" "Group enriched" "Detected in all" 6 "dendritic cells: 309.6;granulocytes: 498.1;monocytes: 454.6" "Cell line enhanced" "Detected in many" "Karpas-707: 135.9;U-266/70: 98.4;U-937: 62.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA027513, HPA031096" Uncertain Approved Nucleoplasm NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 2: Karpas-707 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "HPA027513: , HPA031096: AB_10599254" "unprognostic (7.38e-2)" "unprognostic (6.56e-2)" "unprognostic (5.07e-2)" "unprognostic (1.99e-3)" "unprognostic (4.51e-2)" "unprognostic (5.56e-3)" "unprognostic (4.13e-1)" "unprognostic (8.21e-2)" "unprognostic (1.77e-2)" "unprognostic (3.05e-2)" "unprognostic (1.38e-2)" "unprognostic (8.96e-2)" "unprognostic (7.21e-3)" "unprognostic (5.07e-2)" "unprognostic (1.42e-2)" "unprognostic (2.24e-3)" "unprognostic (4.52e-3)" 30.7 10.6 10.8 72.8 13.1 215.5 12.7 13.6 14.4 7.2 12.3 14.7 10.1 5.7 3.9 8.0 10.2 23.6 6.6 11.2 16.6 9.2 19.1 45.8 47.9 22.2 14.3 3.3 5.4 2.7 4.9 18.8 19.1 5.4 10.1 0.9 11.1 3.9 3.4 4.5 28.2 15.5 15.4 126.0 12.2 22.4 17.8 16.0 11.0 4.5 29.9 26.9 6.4 24.6 9.1 0.3 3.4 0.5 11.4 15.6 1.5 1.9 20.0 28.7 40.2 1.3 2.4 12.8 1.2 6.6 15.9 1.3 5.2 1.2 4.6 1.7 1.2 18.0 0.4 2.3 22.3 23.0 27.8 7.9 0.3 14.8 0.1 1.5 11.1 1.0 24.7 135.9 2.1 6.1 0.9 20.1 11.8 0.3 1.8 4.1 12.8 23.2 8.6 0.3 0.2 5.0 0.1 0.8 26.2 2.1 0.3 20.2 6.9 1.7 0.2 5.6 0.3 98.4 6.1 0.8 32.3 62.1 0.5 41.7 403.3 341.0 71.9 441.4 66.1 41.5 53.1 60.2 309.6 21.8 45.6 48.2 498.1 61.9 454.6 125.2 56.4 380.7 10.8 13.1 13.6 14.4 11.2 16.6 22.2 14.3 19.1 15.4 17.8 24.6 2.2 3.2 20.0 0.3 42.6 3.2 1.1 2.7 0.6 0.4 1.0 0.6 0.7 2.8 8.7 0.0 0.0 0.8 87.5 0.3 0.0 0.9 2.3 4.5 1.8 6.8 10.7 6.1 6.2 8.3 1.3 1.8 1.1 6.4 13.3 7.1 3.6 1.3 62.6 0.0 0.7 0.2 36.7 135.9 59.9 5.2 0.6 125.4 17.8 6.5 144.8 0.1 54.6 0.5 14.7 8.7 0.0 0.4 57.3 3.0 0.0 0.4 3.2 0.2 0.0 21.9 2.1 1.8 2.9 0.1 1.1 2.5 21.2 3.0 0.8 5.0 THNSL2 "FLJ10916, SOFAT, TSH2" ENSG00000144115 "Threonine synthase like 2" Q86YJ6 2 88170295-88186636 "Predicted intracellular proteins, Predicted secreted proteins" "Cytokine, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal tubular cells: 58.7;Proximal tubular cells: 87.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HHSteC: 31.6;MCF7: 12.2;SK-MEL-30: 12.6;SuSa: 15.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035395 Approved "Secreted - unknown location" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA035395: AB_10601600" "unprognostic (1.51e-2)" "unprognostic (1.03e-1)" "unprognostic (2.14e-1)" "unprognostic (1.14e-1)" "unprognostic (4.53e-2)" "unprognostic (8.73e-2)" "unprognostic (6.64e-2)" "unprognostic (7.26e-2)" "unprognostic (1.93e-1)" "unprognostic (3.47e-1)" "unprognostic (1.59e-1)" "unprognostic (1.97e-2)" "unprognostic (2.01e-3)" "unprognostic (6.98e-2)" "unprognostic (8.81e-2)" "unprognostic (1.40e-1)" "unprognostic (1.24e-2)" 13.9 22.6 14.9 2.4 16.9 0.9 16.4 15.1 15.6 14.8 15.0 18.0 5.6 11.2 22.6 6.5 19.2 7.7 17.8 13.8 18.1 28.5 50.0 7.2 1.9 16.7 16.2 14.9 14.2 32.3 29.1 8.6 16.0 22.3 3.7 7.3 12.9 13.5 50.1 9.3 12.6 6.3 16.1 7.5 13.5 13.0 16.7 1.1 21.9 35.8 1.8 12.5 9.9 16.3 0.3 0.0 0.0 0.0 2.7 0.9 1.5 4.6 5.0 6.4 8.3 6.6 7.7 0.0 2.2 0.0 0.0 0.0 0.0 0.2 3.0 0.0 0.1 0.0 0.0 0.0 31.6 0.0 0.6 5.1 10.3 1.9 0.0 0.5 0.0 0.0 0.0 0.0 4.7 12.2 0.0 0.1 6.2 7.1 0.6 0.0 0.0 0.0 5.2 0.5 0.3 0.0 5.4 0.4 12.6 15.0 8.8 2.0 0.0 1.4 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.2 0.3 0.3 0.4 0.2 0.4 0.1 0.2 0.4 0.7 0.2 0.0 0.1 0.0 0.2 0.0 0.0 0.2 14.9 16.9 15.1 15.6 13.8 18.1 16.7 16.2 16.0 16.1 16.7 16.3 2.8 3.2 9.3 13.1 3.1 6.6 8.6 8.3 9.6 12.8 23.2 20.2 17.3 20.0 2.9 14.7 0.0 42.5 0.4 9.2 58.7 14.8 1.3 14.5 8.9 3.6 2.4 6.1 2.8 3.0 15.7 13.8 6.6 8.4 0.0 8.1 7.9 43.6 4.6 13.5 3.0 6.8 4.1 10.7 4.6 4.2 9.0 2.8 14.2 5.6 11.3 43.5 3.1 4.0 16.7 5.4 8.9 9.8 1.7 6.3 13.4 87.2 5.2 7.3 0.0 8.9 6.4 3.7 11.4 3.7 5.1 23.9 1.7 13.8 6.2 5.6 THOC7 "FLJ23445, fSAP24, NIF3L1BP1" ENSG00000163634 "THO complex 7" Q6I9Y2 3 63833870-63863868 "Predicted intracellular proteins" "mRNA processing, mRNA splicing, mRNA transport, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 1032.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044143 Approved Supported "Nuclear speckles,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" "Nuclear speckles, Cytosol" "HPA044143: AB_10794892" "unprognostic (4.33e-2)" "unprognostic (9.68e-2)" "unprognostic (1.75e-2)" "unprognostic (1.30e-1)" "unprognostic (2.26e-2)" "unprognostic (2.86e-1)" "unprognostic (1.20e-3)" "unprognostic (3.53e-2)" "unprognostic (1.85e-2)" "unprognostic (1.52e-2)" "unprognostic (2.86e-2)" "unprognostic (9.90e-2)" "unprognostic (3.26e-2)" "unprognostic (1.51e-2)" "unprognostic (5.18e-2)" "unprognostic (4.25e-2)" "unprognostic (2.31e-1)" 54.7 63.5 57.1 43.2 60.0 80.1 75.1 58.1 85.1 54.4 52.0 69.9 64.2 50.5 53.2 73.1 43.0 48.6 88.0 61.5 59.1 67.8 73.5 40.9 68.1 58.4 59.1 44.4 62.3 52.1 33.5 53.5 57.1 43.8 69.1 64.5 50.5 49.5 103.5 64.2 53.7 59.6 57.3 38.2 49.1 47.6 57.8 72.3 44.4 104.0 68.0 60.8 50.3 61.1 141.2 83.5 95.6 23.9 125.1 172.5 89.6 120.2 126.9 139.2 140.1 101.6 151.5 168.3 49.1 155.1 139.2 79.3 107.5 190.4 194.1 169.6 75.5 150.2 102.8 117.2 130.1 212.6 69.6 123.9 157.2 118.4 213.1 137.6 155.1 110.0 116.8 158.6 170.2 1032.4 186.4 186.9 120.4 304.8 65.5 132.3 89.7 227.4 245.4 128.0 47.3 107.8 105.0 147.6 171.6 93.9 93.6 289.6 113.6 100.8 105.9 125.1 216.3 101.3 162.3 204.1 125.3 268.3 133.5 73.1 40.4 33.1 38.7 47.7 54.0 46.7 47.9 53.2 59.0 31.5 40.5 43.4 23.4 55.6 41.9 54.0 61.7 35.6 57.1 60.0 58.1 85.1 61.5 59.1 58.4 59.1 57.1 57.3 57.8 61.1 82.6 89.8 45.0 14.4 59.2 61.6 91.2 179.9 70.6 53.5 70.9 121.3 143.8 81.5 102.9 84.6 18.8 180.3 66.0 62.1 207.4 145.2 84.7 100.7 75.6 57.8 55.2 159.7 26.8 126.9 166.1 65.4 47.4 73.8 54.4 74.3 44.6 78.1 111.6 48.8 26.4 106.3 101.7 75.6 58.9 89.7 88.9 70.2 67.6 14.0 173.1 82.5 93.7 12.5 18.9 127.6 86.7 71.5 53.3 96.6 108.8 241.2 102.1 73.1 52.6 66.9 83.4 244.9 54.5 116.6 71.6 213.4 68.0 80.7 133.2 95.7 THSD4 "ADAMTSL6, FLJ13710, FVSY9334, PRO34005" ENSG00000187720 "Thrombospondin type 1 domain containing 4" Q6ZMP0 15 71096952-71783383 "Predicted membrane proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 103.7" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 106.4;Basal squamous epithelial cells: 449.0;Microglial cells: 247.3;Squamous epithelial cells: 141.5" "Cancer enhanced" "Detected in many" "ovarian cancer: 18.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 45.3;BJ hTERT+: 53.0;T-47d: 43.3;TIME: 66.6;U-2197: 44.4" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 4 "spinal cord: 39.0" "Secreted - unknown location" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "unprognostic (1.59e-1)" "unprognostic (4.38e-2)" "unprognostic (3.14e-2)" "unprognostic (1.04e-1)" "unprognostic (1.52e-1)" "unprognostic (2.82e-2)" "unprognostic (2.63e-2)" "unprognostic (1.14e-1)" "unprognostic (7.80e-2)" "unprognostic (2.51e-2)" "unprognostic (1.13e-1)" "unprognostic (9.67e-2)" "unprognostic (1.43e-1)" "unprognostic (3.64e-1)" "unprognostic (1.30e-1)" "unprognostic (1.33e-2)" "unprognostic (3.01e-3)" 4.8 8.4 9.8 1.6 7.8 0.0 14.7 6.1 8.6 103.7 9.5 7.0 7.9 22.2 7.8 60.3 37.0 10.9 41.6 8.5 7.2 14.2 7.0 10.3 0.9 7.8 9.1 3.1 6.4 0.7 9.7 3.6 7.6 34.0 6.9 1.2 11.4 15.0 3.0 8.5 8.7 10.3 7.0 1.9 12.0 3.1 15.9 1.6 8.8 2.5 2.5 13.3 38.5 5.9 6.0 45.3 0.8 13.0 6.7 40.2 0.2 22.0 53.0 11.2 5.8 0.3 8.7 0.0 17.7 7.8 38.5 17.0 1.8 9.1 6.8 2.0 2.0 0.0 4.4 0.0 4.3 0.0 0.0 3.0 6.7 6.7 26.6 30.5 20.7 0.0 0.0 0.5 9.2 9.1 0.0 0.1 3.9 0.1 7.8 0.0 0.7 0.8 29.5 6.0 0.7 5.5 8.8 10.9 0.0 5.0 43.3 0.1 66.6 0.2 1.0 44.4 11.8 0.0 0.3 0.0 10.4 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 7.8 6.1 8.6 8.5 7.2 7.8 9.1 7.6 7.0 15.9 5.9 1.1 19.2 9.0 6.5 0.0 13.9 106.4 11.3 449.0 3.0 48.7 43.9 60.1 58.6 7.5 5.5 6.2 0.4 0.8 16.2 1.9 18.3 7.5 19.3 13.2 9.8 3.0 0.0 17.1 1.8 0.4 12.5 2.6 31.8 0.0 0.3 6.1 12.3 0.2 0.0 19.1 6.1 0.0 0.0 2.1 16.9 17.4 1.6 8.8 247.3 0.0 0.3 0.0 8.5 6.7 13.6 11.0 74.4 1.2 94.6 29.3 0.5 11.0 0.9 0.0 16.8 6.6 0.9 1.7 141.5 10.9 0.8 3.1 42.2 13.2 29.7 THUMPD3 DKFZP434F091 ENSG00000134077 "THUMP domain containing 3" Q9BV44 3 9362971-9386791 "Predicted intracellular proteins" "Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 270.0;Late spermatids: 145.3;Spermatocytes: 183.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036170, HPA036171" Approved Enhanced Nucleoli,Cytosol No No "Cluster 44: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 16: U-266 - Nucleosome" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol Nucleoli "HPA036170: AB_10671836, HPA036171: AB_2674985" "unprognostic (2.13e-2)" "unprognostic (8.30e-2)" "unprognostic (1.74e-3)" "unprognostic (4.25e-2)" "unprognostic (2.66e-2)" "unprognostic (2.04e-1)" "prognostic unfavorable (1.25e-7)" "unprognostic (6.54e-2)" "unprognostic (1.09e-1)" "unprognostic (2.60e-1)" "unprognostic (1.00e-1)" "unprognostic (4.19e-2)" "prognostic favorable (1.03e-4)" "unprognostic (1.41e-1)" "unprognostic (4.53e-2)" "unprognostic (4.05e-2)" "unprognostic (1.59e-2)" 14.5 15.5 10.1 15.0 11.5 33.0 18.0 12.7 11.0 18.1 14.0 19.1 16.8 16.3 16.7 20.9 14.7 13.6 24.6 9.9 11.7 20.0 23.4 14.2 18.8 11.2 10.6 14.7 15.5 25.8 12.1 15.1 12.0 19.5 19.0 22.0 15.9 17.9 26.9 13.6 14.3 14.4 11.6 14.3 14.1 59.4 10.9 18.3 23.1 26.4 17.7 16.4 9.6 15.2 40.0 53.0 36.4 18.7 46.5 44.4 146.3 47.2 38.3 47.1 35.8 40.2 41.0 41.0 35.8 43.5 74.1 26.0 66.4 48.3 47.9 45.6 39.1 51.0 51.2 35.3 44.8 66.0 35.3 36.2 53.7 55.7 58.1 38.0 31.5 65.1 80.2 58.2 62.9 55.3 78.9 27.2 69.3 44.0 50.1 49.4 62.7 57.9 29.7 60.4 15.5 48.9 39.6 27.5 43.5 37.2 45.2 42.1 22.8 45.0 38.9 54.9 53.1 73.1 186.7 129.2 55.0 60.5 65.7 19.1 17.8 17.6 20.5 23.4 26.2 17.2 17.6 21.9 20.8 20.0 28.0 21.5 3.6 17.7 29.0 20.5 18.4 14.1 10.1 11.5 12.7 11.0 9.9 11.7 11.2 10.6 12.0 11.6 10.9 15.2 14.9 25.6 21.8 10.1 14.0 10.7 29.3 42.6 16.5 21.6 19.5 23.2 45.3 17.2 34.6 22.0 16.7 34.7 13.1 10.0 52.8 39.2 270.0 19.2 26.8 14.9 3.0 9.7 9.7 29.4 28.4 22.3 12.2 20.9 28.4 21.9 13.2 25.3 27.4 38.7 13.2 15.5 38.7 14.8 6.8 145.3 20.5 18.0 12.4 9.4 20.2 31.4 18.6 18.1 12.5 28.2 9.8 25.9 16.2 32.6 10.9 32.6 20.1 35.2 6.6 28.5 24.5 183.5 52.9 18.9 12.9 27.5 18.4 49.2 20.0 20.9 TIAM2 STEF ENSG00000146426 "TIAM Rac1 associated GEF 2" Q8IVF5 6 154832697-155257723 "Metabolic proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.8;testis: 13.3" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 81.3;Early spermatids: 141.5;Excitatory neurons: 74.2;Late spermatids: 347.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 6.4;non-classical monocyte: 9.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 65.7;HDLM-2: 27.8;RH-30: 43.3" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "olfactory bulb: 36.9" "HPA011134, HPA013903" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" No No "Cluster 51: Monocytes - Innate immune response" "Cluster 78: Testis - Spermatogenesis" "Cluster 12: NES - Nervous system development" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Nucleoli fibrillar center" Cytosol "HPA011134: AB_1858005, HPA013903: AB_1858004" "unprognostic (9.14e-2)" "unprognostic (5.79e-2)" "unprognostic (1.44e-1)" "unprognostic (6.38e-2)" "unprognostic (1.08e-1)" "unprognostic (1.69e-1)" "unprognostic (4.36e-2)" "unprognostic (1.89e-1)" "unprognostic (5.74e-2)" "unprognostic (1.81e-2)" "unprognostic (1.84e-2)" "unprognostic (1.36e-2)" "unprognostic (1.38e-3)" "unprognostic (1.82e-1)" "unprognostic (8.13e-2)" "unprognostic (6.04e-2)" "unprognostic (1.05e-1)" 0.4 1.2 2.8 0.9 7.1 0.4 1.2 5.4 11.8 1.1 0.0 1.2 8.3 0.8 0.6 0.6 0.8 2.2 2.2 6.1 0.0 0.3 0.3 0.5 1.2 0.4 1.0 0.3 1.3 0.1 1.4 0.5 0.0 2.0 0.8 3.3 1.3 2.7 2.5 0.6 7.9 1.1 0.4 0.7 3.0 13.3 0.8 0.6 5.5 1.7 2.0 2.0 0.7 6.1 8.3 1.5 65.7 6.1 2.9 7.9 0.4 3.2 2.2 3.3 5.5 0.7 4.8 1.1 3.1 6.3 0.9 0.5 2.4 0.0 2.3 27.8 3.3 0.0 1.1 1.9 1.8 0.2 1.7 5.4 0.2 1.1 0.2 2.5 4.7 0.5 0.2 0.1 7.5 0.5 0.7 0.7 4.1 0.1 1.3 8.4 43.3 0.3 0.2 0.2 1.1 14.5 0.1 0.3 0.2 11.9 0.3 0.6 1.5 0.2 15.5 0.4 1.5 0.2 3.6 0.2 0.0 0.3 3.9 0.0 0.0 2.1 0.0 2.0 0.0 2.0 0.1 0.1 0.3 0.7 0.0 0.0 6.4 0.4 9.5 0.0 1.2 0.1 2.8 7.1 5.4 11.8 6.1 0.0 0.4 1.0 0.0 0.4 0.8 6.1 2.9 3.2 2.6 8.8 9.6 3.1 22.5 2.8 1.8 14.3 3.3 5.3 8.3 7.2 2.1 1.8 81.3 1.8 4.3 2.2 0.0 5.3 141.5 8.3 4.9 2.7 0.0 3.6 74.2 3.1 2.6 4.4 6.1 12.1 19.7 6.8 11.0 1.5 1.9 23.5 31.4 3.9 6.1 2.2 2.2 347.4 9.9 5.2 12.4 4.7 9.8 7.6 4.1 28.6 5.1 5.9 5.8 7.9 13.3 9.6 23.9 1.0 3.3 23.9 0.0 7.0 4.3 6.7 7.3 2.1 2.6 0.4 5.0 5.3 3.9 11.6 TIGD5 FLJ14926 ENSG00000179886 "Tigger transposable element derived 5" Q53EQ6 8 143597831-143603224 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 20.9;Theca cells: 29.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HDLM-2: 5.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 50: Non-specific - Ribosome" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" "unprognostic (1.90e-1)" "unprognostic (7.91e-2)" "unprognostic (1.21e-1)" "unprognostic (5.24e-2)" "unprognostic (1.22e-1)" "unprognostic (2.87e-2)" "prognostic unfavorable (7.68e-4)" "unprognostic (2.79e-2)" "unprognostic (1.12e-1)" "unprognostic (6.72e-2)" "unprognostic (2.75e-3)" "unprognostic (3.16e-1)" "prognostic favorable (9.16e-5)" "unprognostic (1.44e-2)" "unprognostic (1.34e-1)" "unprognostic (2.32e-1)" "unprognostic (4.04e-1)" 2.1 2.9 1.8 0.2 1.6 0.1 2.1 4.0 2.0 3.0 0.5 3.1 0.4 3.2 0.1 3.5 3.0 0.2 3.6 1.5 1.6 3.0 2.3 1.7 0.3 2.1 2.0 4.0 5.9 0.7 3.8 0.1 1.7 3.0 0.1 0.1 2.7 0.3 4.4 3.7 2.7 0.1 1.5 3.6 3.0 1.5 1.7 0.2 3.0 0.4 0.2 3.2 2.5 2.0 0.9 1.5 0.4 1.2 0.6 0.6 0.6 0.5 0.4 0.5 0.4 0.5 0.6 1.7 2.7 0.4 0.5 1.2 0.4 0.4 0.0 5.9 1.8 1.0 1.7 0.2 1.1 0.4 1.4 0.6 1.1 0.3 0.5 0.7 0.4 0.4 1.2 0.2 0.2 1.6 2.9 1.7 0.6 1.0 2.9 1.1 0.3 0.8 0.5 0.6 1.4 1.8 1.1 0.9 1.2 0.1 2.6 1.2 0.7 1.0 0.8 1.0 3.5 0.9 0.4 0.2 0.6 0.7 0.7 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.8 1.6 4.0 2.0 1.5 1.6 2.1 2.0 1.7 1.5 1.7 2.0 5.0 3.2 1.3 0.7 3.8 1.7 5.4 0.9 1.2 16.0 6.3 4.6 5.9 4.3 1.3 5.5 20.9 1.4 4.9 5.1 0.0 2.3 1.0 4.0 8.1 4.4 0.0 4.0 0.8 1.8 1.3 4.2 2.0 5.5 1.3 15.4 4.6 2.6 3.4 16.8 1.1 3.6 0.0 3.2 0.8 0.7 7.8 3.0 0.0 1.0 3.2 10.0 6.2 0.5 0.4 3.6 1.7 4.5 1.0 4.9 3.3 2.2 1.1 15.1 0.0 10.6 4.2 0.8 1.2 2.4 1.0 1.8 3.5 29.3 5.1 3.8 TIMD4 TIM4 ENSG00000145850 "T cell immunoglobulin and mucin domain containing 4" Q96H15 5 156919292-156963226 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "lymphoid tissue: 55.3;testis: 144.0" "Group enriched" "Detected in some" 23 "Early spermatids: 1336.2;Late spermatids: 1946.7" "Cancer enriched" "Detected in some" 10 "renal cancer: 6.2" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 5 "memory CD4 T-cell: 1.3;memory CD8 T-cell: 2.4;naive CD4 T-cell: 1.6;naive CD8 T-cell: 1.6;T-reg: 4.0" "Lineage enriched" "Detected in single" 18 "T-cells: 4.0" "Group enriched" "Detected in some" 18 "U-266/70: 96.7;U-266/84: 28.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA015625, CAB026027" Approved Approved "Plasma membrane" NA NA 32000000 "Cluster 35: T-regs - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 34: Spermatids - Unknown function" "Plasma membrane" "CAB026027: , HPA015625: AB_1858018" "unprognostic (2.92e-1)" "unprognostic (1.06e-2)" "unprognostic (1.73e-1)" "unprognostic (2.31e-1)" "unprognostic (1.80e-1)" "unprognostic (3.01e-2)" "unprognostic (1.10e-1)" "unprognostic (3.11e-1)" "unprognostic (3.42e-1)" "unprognostic (8.42e-2)" "unprognostic (1.10e-1)" "unprognostic (6.90e-2)" "prognostic favorable (3.37e-4)" "unprognostic (1.31e-2)" "unprognostic (4.07e-1)" "unprognostic (3.27e-2)" "unprognostic (2.08e-2)" 14.9 0.4 0.4 6.9 0.3 16.1 0.4 0.3 1.4 0.1 1.8 1.1 0.4 0.0 1.3 0.1 0.1 1.3 0.7 0.5 0.4 3.4 16.3 1.6 55.3 0.5 0.4 0.0 0.2 0.1 0.0 5.0 0.5 0.3 0.8 0.0 0.2 0.0 0.1 0.3 1.7 1.0 0.3 8.0 0.2 144.0 0.5 22.4 1.1 0.0 17.4 4.8 0.1 0.5 0.1 3.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.4 0.0 0.6 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 96.7 28.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 1.3 2.4 0.0 0.0 1.6 1.6 0.0 0.0 0.0 0.0 4.0 0.7 0.4 0.3 0.3 1.4 0.5 0.4 0.5 0.4 0.5 0.3 0.5 0.5 0.1 0.0 0.0 0.0 1.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.4 0.4 5.9 0.1 1336.2 0.3 0.0 0.5 0.0 0.0 0.4 0.0 0.7 0.1 0.5 0.0 0.0 0.0 0.7 0.3 46.4 0.0 0.3 0.0 0.0 69.4 1.9 1946.7 14.9 1.9 0.0 2.8 0.0 0.0 1.0 0.0 0.3 0.0 0.0 10.9 6.5 0.0 0.0 0.8 0.0 0.0 13.1 0.0 0.1 16.6 8.1 0.0 0.0 0.3 1.7 0.1 0.1 0.0 TIMELESS "hTIM, TIM, TIM1" ENSG00000111602 "Timeless circadian regulator" Q9UNS1 12 56416363-56449426 "Predicted intracellular proteins" "Biological rhythms, Cell cycle, Cell division, DNA damage, DNA repair, Mitosis, Transcription, Transcription regulation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 57.5;Spermatogonia: 24.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" HPA060655 Enhanced Supported Nucleoplasm No No "Cluster 21: B-cells - Adaptive immune response" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA060655: AB_2684338" "unprognostic (3.94e-2)" "unprognostic (1.10e-2)" "unprognostic (1.29e-2)" "unprognostic (2.18e-2)" "unprognostic (2.36e-1)" "unprognostic (3.06e-2)" "prognostic unfavorable (3.61e-4)" "unprognostic (1.43e-3)" "prognostic unfavorable (1.06e-5)" "unprognostic (7.03e-2)" "unprognostic (2.53e-1)" "unprognostic (1.48e-2)" "prognostic unfavorable (2.61e-5)" "unprognostic (9.47e-3)" "unprognostic (1.72e-1)" "unprognostic (1.92e-2)" "unprognostic (5.01e-2)" 3.4 3.4 1.6 11.0 2.1 22.0 4.5 2.1 2.1 4.1 2.7 6.7 6.0 4.4 2.5 6.8 3.1 3.3 1.8 1.5 2.1 3.8 9.8 4.1 15.3 2.4 2.4 1.9 5.0 5.9 5.4 8.7 2.5 3.2 8.5 13.7 3.9 3.4 3.4 5.5 6.2 5.6 2.1 6.8 5.5 6.2 2.6 19.8 4.7 1.6 17.9 4.7 3.9 2.5 39.4 89.1 111.4 51.9 9.9 9.9 62.8 41.9 25.3 58.3 46.0 45.6 56.5 113.3 41.5 24.5 29.4 32.8 82.0 32.7 53.5 54.2 45.7 86.9 47.6 33.6 5.1 66.2 62.2 6.9 10.3 41.9 25.2 16.0 31.5 67.3 82.7 99.5 49.8 77.2 94.7 51.2 79.2 49.5 36.8 93.5 56.7 55.5 22.7 49.5 85.4 58.9 78.2 43.9 12.2 45.6 77.4 51.8 18.9 45.3 45.1 41.8 35.0 37.3 50.9 62.8 21.1 39.9 55.5 0.1 0.6 0.4 1.8 1.5 0.3 3.3 1.1 1.2 1.0 4.9 0.8 0.3 0.2 1.5 1.1 1.2 1.5 1.1 1.6 2.1 2.1 2.1 1.5 2.1 2.4 2.4 2.5 2.1 2.6 2.5 2.6 0.0 5.0 2.3 8.2 3.3 3.0 3.0 6.8 57.5 3.1 3.4 2.1 2.8 6.8 7.3 2.1 15.9 1.8 2.7 0.0 4.8 6.9 2.5 3.9 5.0 1.8 16.6 0.9 5.7 20.9 3.7 6.6 4.8 5.7 15.5 4.6 10.6 8.5 6.7 1.3 5.2 4.1 2.6 3.7 2.9 1.2 4.6 0.0 1.9 4.2 4.8 4.1 0.5 3.2 3.7 0.6 1.2 18.2 4.2 1.1 2.0 3.4 17.8 0.0 2.7 7.0 1.6 24.5 12.1 1.4 9.2 6.1 3.2 8.5 3.0 TINAGL1 "ARG1, LCN7, LIECG3, P3ECSL, TINAGRP" ENSG00000142910 "Tubulointerstitial nephritis antigen like 1" Q9GZM7 1 31576485-31587686 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1235.1;Sertoli cells: 427.3;Syncytiotrophoblasts: 1946.1" "Cancer enhanced" "Detected in all" "urothelial cancer: 87.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.0" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.0" "Cell line enhanced" "Detected in many" "BEWO: 322.7;CAPAN-2: 178.9;EFO-21: 403.6;HaCaT: 181.4;HBEC3-KT: 211.9;HUVEC TERT2: 173.4;TIME: 376.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048695 Approved "Secreted to extracellular matrix" NA NA 370000 "Cluster 17: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" "HPA048695: AB_2680497" "unprognostic (1.27e-1)" "unprognostic (2.94e-2)" "unprognostic (7.53e-2)" "unprognostic (1.80e-3)" "unprognostic (2.74e-1)" "unprognostic (1.72e-3)" "unprognostic (8.29e-3)" "unprognostic (6.02e-3)" "unprognostic (4.18e-1)" "unprognostic (6.96e-2)" "unprognostic (7.02e-3)" "unprognostic (1.22e-1)" "prognostic favorable (3.65e-6)" "unprognostic (7.42e-2)" "unprognostic (6.64e-2)" "prognostic favorable (9.64e-4)" "unprognostic (3.43e-2)" 173.7 40.8 19.0 18.5 17.7 0.9 150.5 17.9 19.9 86.8 16.4 83.2 26.7 101.8 10.7 31.0 82.4 23.9 230.7 15.2 17.9 177.7 22.7 85.7 8.5 19.6 18.3 38.8 31.0 13.2 25.3 183.6 19.8 71.2 16.5 1.0 63.8 40.6 46.6 37.0 51.6 36.5 16.4 119.6 66.4 6.2 21.2 3.8 115.1 30.6 5.3 88.4 70.2 17.1 96.6 0.2 0.0 0.5 0.8 0.2 322.7 14.9 1.9 0.7 0.4 44.5 178.9 0.2 403.6 13.4 7.0 181.4 0.2 211.9 0.1 0.7 0.1 0.1 7.3 11.5 4.5 0.1 0.5 0.2 37.9 0.0 7.6 0.1 173.4 0.1 2.4 0.4 0.0 0.0 0.7 0.6 0.9 52.6 6.1 0.4 0.1 0.4 57.0 72.6 0.4 0.5 38.0 125.6 4.2 18.8 7.5 0.3 376.6 0.3 91.6 0.7 2.8 0.4 0.5 1.6 0.2 0.2 3.3 2.0 0.1 0.1 0.2 0.0 0.1 0.1 0.1 0.1 0.0 0.3 0.2 0.2 0.8 0.4 0.1 0.1 0.1 0.0 19.0 17.7 17.9 19.9 15.2 17.9 19.6 18.3 19.8 16.4 21.2 17.1 345.4 9.6 5.8 0.7 2.7 11.0 121.5 244.1 8.0 0.0 32.0 73.0 46.7 37.1 28.6 132.4 0.0 1235.1 2.6 158.9 1.9 378.7 1.4 8.4 3.2 161.4 11.4 13.5 0.1 92.2 223.5 35.0 50.0 14.4 14.7 49.7 306.6 4.4 89.3 0.0 1.1 35.5 14.2 8.8 10.3 0.7 7.5 4.2 23.2 13.1 2.0 0.2 0.0 0.5 0.0 344.6 115.3 4.1 0.2 131.4 45.2 80.9 9.1 0.4 427.3 9.5 357.4 0.3 0.8 4.9 6.5 1946.1 3.8 2.7 59.7 219.4 TIPARP "ARTD14, DDF1, DKFZP434J214, DKFZp686N0351, PARP-1, PARP-7, PARP7, pART14, RM1" ENSG00000163659 "TCDD inducible poly(ADP-ribose) polymerase" Q7Z3E1 3 156673235-156706770 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 302.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 53.5" "Lineage enriched" "Detected in all" 5 "granulocytes: 53.5" "Cell line enhanced" "Detected in all" "HBEC3-KT: 168.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036796 Approved Microtubules NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 23: Testis - Cell cycle regulation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" Microtubules "HPA036796: AB_10672268" "prognostic favorable (2.00e-5)" "unprognostic (3.50e-1)" "unprognostic (7.62e-2)" "unprognostic (5.21e-2)" "unprognostic (2.62e-1)" "unprognostic (4.56e-2)" "unprognostic (9.50e-2)" "unprognostic (3.57e-2)" "unprognostic (2.23e-1)" "unprognostic (1.43e-1)" "unprognostic (4.27e-3)" "unprognostic (2.01e-1)" "unprognostic (4.69e-2)" "unprognostic (7.26e-2)" "unprognostic (1.73e-1)" "unprognostic (6.16e-3)" "unprognostic (4.90e-3)" 67.5 56.6 16.5 16.0 19.3 74.1 39.7 17.7 22.3 29.8 15.2 15.1 13.5 30.6 14.7 55.1 39.5 27.9 34.6 16.4 21.2 28.2 44.3 27.4 13.7 33.4 27.9 40.2 29.6 99.2 15.1 12.5 22.9 25.9 14.4 18.3 10.3 27.8 17.6 39.5 23.1 43.7 19.9 10.9 21.9 50.3 25.7 21.7 17.0 9.6 18.1 65.0 24.0 21.9 42.8 29.6 9.8 8.4 35.7 25.9 8.0 70.0 56.4 34.9 48.2 17.2 86.9 12.7 22.2 79.9 46.5 42.1 25.1 168.0 51.4 27.3 18.5 21.0 29.0 11.7 15.2 7.4 38.1 21.3 103.0 35.6 84.9 93.8 32.3 9.4 16.9 49.9 122.5 8.2 6.4 9.8 11.2 53.5 24.5 10.5 22.5 43.6 36.7 20.1 29.5 7.5 55.2 16.9 11.9 22.5 26.2 12.5 70.2 15.1 4.9 28.5 25.1 53.9 10.6 11.3 25.7 11.3 51.4 53.5 5.0 7.5 6.1 3.3 8.6 2.9 5.9 8.2 3.6 5.4 3.6 4.9 15.9 11.6 9.2 5.0 7.4 3.3 16.5 19.3 17.7 22.3 16.4 21.2 33.4 27.9 22.9 19.9 25.7 21.9 112.8 86.6 98.3 27.7 43.9 196.0 117.3 51.7 185.5 5.0 62.0 57.7 29.9 31.5 66.5 7.3 39.6 5.1 97.0 38.3 21.5 35.2 302.3 114.6 118.7 45.6 54.5 7.0 3.6 23.5 10.3 109.0 57.6 169.4 115.0 12.2 20.3 18.9 19.2 21.9 8.7 32.4 18.3 18.5 97.5 28.0 19.6 101.7 37.4 12.2 17.3 10.1 16.5 22.1 20.4 36.9 40.1 19.2 60.5 83.9 40.4 16.2 43.5 10.4 13.1 138.0 87.7 58.0 33.4 100.1 121.5 7.5 105.4 7.3 18.2 187.8 TLCD4 "FLJ31842, TMEM56" ENSG00000152078 "TLC domain containing 4" Q96MV1 1 95117355-95197607 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 130.0" "Cell type enriched" "Detected in some" 9 "Cardiomyocytes: 77.9" "Cancer enhanced" "Detected in many" "liver cancer: 13.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 22.4;RH-30: 35.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046762 Approved "Nuclear speckles" No No "Cluster 19: B-cells - Humoral immune response" "Cluster 85: Liver - Metabolism" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nuclear speckles" "HPA046762: AB_2679792" "unprognostic (1.51e-3)" "unprognostic (1.54e-1)" "unprognostic (2.98e-3)" "unprognostic (2.79e-1)" "unprognostic (3.30e-2)" "unprognostic (2.31e-1)" "unprognostic (3.82e-3)" "unprognostic (3.63e-2)" "unprognostic (4.42e-3)" "unprognostic (2.69e-2)" "unprognostic (4.99e-2)" "unprognostic (4.40e-2)" "unprognostic (1.16e-3)" "unprognostic (1.10e-1)" "unprognostic (9.46e-2)" "unprognostic (1.59e-1)" "unprognostic (3.15e-2)" 5.3 9.9 9.4 2.1 10.6 20.5 2.6 19.5 15.1 2.4 0.0 13.6 5.5 3.4 2.5 2.3 2.4 4.2 25.7 10.6 6.3 5.7 130.0 3.7 0.4 4.9 5.7 1.7 7.4 6.4 3.4 4.4 4.2 5.3 10.2 3.1 8.3 2.9 13.0 1.6 8.5 3.6 6.9 0.7 5.0 4.8 9.9 0.3 7.3 9.7 0.5 4.7 1.3 12.6 22.4 12.6 1.7 2.6 0.8 0.0 2.9 0.8 0.5 2.8 6.5 9.1 10.4 0.0 10.7 0.4 20.0 0.2 7.4 1.1 4.8 15.5 4.1 0.5 9.2 2.0 0.8 0.4 0.6 1.2 0.4 2.1 0.0 4.4 0.0 1.2 19.8 1.2 0.6 1.9 1.3 0.1 1.7 0.7 6.9 0.0 35.7 0.6 12.0 14.4 4.5 3.6 15.6 10.8 6.7 1.8 11.7 0.4 0.2 0.3 9.0 1.1 7.9 3.8 8.0 0.0 1.5 0.1 2.3 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 9.4 10.6 19.5 15.1 10.6 6.3 4.9 5.7 4.2 6.9 9.9 12.6 5.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 77.9 0.0 0.0 0.0 0.0 8.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.5 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 TLCD5 "MGC17839, TMEM136" ENSG00000181264 "TLC domain containing 5" Q6ZRR5 11 120325296-120333686 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "retina: 51.9" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 28.3;Cytotrophoblasts: 10.0;Extravillous trophoblasts: 4.2;Fibroblasts: 6.1;Syncytiotrophoblasts: 9.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "plasmacytoid DC: 2.2" "Lineage enriched" "Detected in single" 5 "dendritic cells: 2.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074432 Approved Vesicles,Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 12: NES - Nervous system development" "Cluster 24: Non-specific - Transcription regulation" Vesicles Cytosol "HPA074432: AB_2686689" "unprognostic (1.02e-1)" "unprognostic (6.56e-2)" "unprognostic (1.49e-2)" "prognostic unfavorable (6.65e-4)" "unprognostic (1.65e-2)" "unprognostic (3.31e-2)" "unprognostic (6.81e-3)" "unprognostic (1.22e-1)" "unprognostic (1.39e-2)" "unprognostic (2.58e-1)" "unprognostic (2.86e-3)" "unprognostic (2.39e-1)" "unprognostic (2.71e-2)" "unprognostic (2.78e-2)" "unprognostic (1.34e-1)" "unprognostic (1.73e-1)" "unprognostic (7.28e-2)" 4.4 13.1 11.3 1.0 15.2 0.2 3.3 13.4 10.9 5.0 8.8 2.8 0.6 5.1 7.6 1.5 5.7 3.2 11.0 10.9 12.1 3.6 0.8 4.8 1.4 12.3 15.3 7.7 3.9 4.5 7.0 7.2 12.0 4.9 1.1 51.9 2.0 3.3 1.2 1.3 1.9 3.8 11.3 2.6 2.5 3.1 12.6 0.8 5.4 1.9 1.4 3.5 3.5 14.0 2.4 6.0 15.8 10.9 10.9 16.8 3.0 5.0 12.3 8.4 12.7 3.2 10.2 0.0 15.3 3.2 16.2 1.6 10.1 3.8 9.8 0.0 6.3 8.1 6.1 5.4 12.4 0.0 0.0 14.7 2.8 11.4 17.0 19.7 9.2 9.5 2.2 14.8 10.9 2.9 0.0 0.1 5.1 0.6 3.8 6.3 4.9 0.8 10.4 2.2 8.3 7.2 7.3 0.9 1.5 13.4 9.3 0.2 6.9 8.7 9.0 2.0 3.1 0.2 0.0 0.0 2.6 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.4 0.0 11.3 15.2 13.4 10.9 10.9 12.1 12.3 15.3 12.0 11.3 12.6 14.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.3 0.0 0.0 0.0 0.0 10.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 4.2 6.1 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 9.4 0.0 0.0 0.0 0.0 TLE1 "ESG, ESG1, GRG1" ENSG00000196781 "TLE family member 1, transcriptional corepressor" Q04724 9 81583683-81689547 "Predicted intracellular proteins" "Transcription, Transcription regulation, Wnt signaling pathway" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 205.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011482, HPA071396" Supported Supported Nucleoplasm NA NA "Cluster 10: Basophils - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 28: BEWO - Transcription regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm "CAB011482: AB_443210, HPA071396: AB_2686392" "unprognostic (5.86e-2)" "unprognostic (2.59e-1)" "unprognostic (3.71e-1)" "unprognostic (8.49e-2)" "unprognostic (2.62e-1)" "unprognostic (4.18e-2)" "unprognostic (1.49e-2)" "unprognostic (2.19e-3)" "unprognostic (3.59e-2)" "unprognostic (3.75e-2)" "unprognostic (4.95e-2)" "unprognostic (3.65e-1)" "prognostic favorable (8.07e-4)" "unprognostic (2.56e-1)" "unprognostic (1.55e-1)" "prognostic unfavorable (7.60e-4)" "unprognostic (4.09e-1)" 44.9 40.1 36.1 11.8 31.8 40.0 39.0 23.1 35.5 57.4 11.7 39.3 7.7 50.1 27.1 20.3 43.0 27.3 19.3 41.2 22.1 21.4 80.7 23.5 12.7 20.7 32.3 42.0 59.9 6.3 19.1 19.3 20.2 31.0 21.6 11.1 47.5 17.4 90.7 31.8 30.2 33.3 20.1 44.7 38.2 25.8 27.6 6.6 24.9 22.5 13.5 30.2 35.5 23.3 69.9 50.6 49.7 0.2 50.3 28.3 99.6 3.9 12.4 8.6 11.3 8.8 26.2 0.0 43.1 27.6 69.0 40.9 1.0 22.3 8.3 0.2 40.0 0.0 12.0 74.8 24.5 0.0 1.3 12.4 47.2 26.2 57.1 22.6 35.1 20.0 0.3 22.4 25.8 74.2 9.8 0.4 88.6 48.0 26.1 66.9 35.2 4.9 46.1 38.2 25.2 31.0 4.8 39.6 22.2 53.3 27.9 31.4 27.6 21.7 22.5 10.5 30.8 0.5 0.3 1.6 28.0 0.2 41.0 8.4 0.0 4.6 2.1 0.0 2.9 6.6 0.2 0.9 0.6 5.8 0.0 0.2 0.0 4.3 0.1 1.7 0.0 0.6 36.1 31.8 23.1 35.5 41.2 22.1 20.7 32.3 20.2 20.1 27.6 23.3 66.6 0.0 6.5 121.5 52.4 54.6 22.3 9.8 18.8 36.6 33.5 18.4 5.7 41.5 15.8 14.7 16.7 67.2 63.5 49.5 15.6 40.8 1.7 85.9 76.2 38.2 28.8 13.9 36.5 23.8 71.9 27.5 23.9 205.8 0.0 30.1 27.1 65.3 7.8 16.8 23.5 24.0 36.7 6.4 20.5 3.6 22.7 9.6 46.2 46.9 8.1 39.5 68.0 22.6 14.5 54.8 41.0 34.3 35.1 40.5 12.2 3.0 17.1 6.0 118.3 12.8 47.4 2.2 102.4 29.3 43.8 50.8 18.6 71.4 48.6 69.4 TLE7 ENSG00000260734 "TLE family member 7" A0A1W2PR48 16 71429980-71442054 "Predicted intracellular proteins" "Evidence at protein level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 26 "testis cancer: 1.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "unprognostic (2.29e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TLK2 "MGC44450, PKU-ALPHA" ENSG00000146872 "Tousled like kinase 2" Q86UE8 17 62458658-62615481 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA damage" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 173.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (2.50e-2)" "unprognostic (2.12e-1)" "unprognostic (7.06e-2)" "unprognostic (1.48e-2)" "unprognostic (9.53e-3)" "unprognostic (6.57e-2)" "prognostic unfavorable (9.40e-4)" "unprognostic (4.53e-2)" "unprognostic (5.28e-2)" "unprognostic (2.32e-1)" "unprognostic (2.82e-2)" "unprognostic (4.78e-2)" "unprognostic (5.32e-2)" "unprognostic (9.79e-2)" "unprognostic (4.32e-2)" "unprognostic (4.88e-1)" "unprognostic (7.30e-2)" 19.9 16.9 7.5 21.1 14.9 36.1 11.8 19.8 12.0 12.4 9.5 21.7 20.5 22.9 8.7 23.6 13.2 20.9 22.6 9.8 17.5 15.2 12.5 16.2 25.5 18.1 14.2 21.6 18.0 16.0 9.8 17.4 14.4 16.0 14.8 43.4 16.5 11.4 32.4 23.7 20.5 16.1 10.0 21.4 18.6 52.1 12.8 23.2 30.0 21.8 17.2 19.1 10.9 25.5 40.9 36.9 62.2 66.4 20.3 26.0 36.6 44.1 34.4 51.7 46.6 39.0 35.7 79.0 22.0 29.2 45.1 27.2 45.1 19.0 48.9 42.3 36.1 54.2 33.6 39.2 36.2 57.9 33.1 22.7 25.4 34.7 41.7 31.2 25.9 44.9 54.4 36.0 28.3 89.2 82.7 22.0 39.8 24.4 30.9 55.9 81.8 25.7 24.9 40.7 66.9 90.6 37.6 25.5 57.1 52.0 43.2 51.8 34.9 71.2 66.9 32.5 50.6 40.1 54.5 72.3 29.4 29.1 38.2 2.5 1.4 4.9 1.2 1.2 1.3 2.2 2.1 1.5 1.3 2.2 1.7 2.3 2.8 3.9 1.3 1.9 2.8 0.9 7.5 14.9 19.8 12.0 9.8 17.5 18.1 14.2 14.4 10.0 12.8 25.5 27.5 32.1 26.7 33.6 22.1 22.7 14.4 9.6 9.1 62.2 17.3 14.0 27.3 11.5 11.6 14.7 83.4 11.5 29.5 19.9 11.7 10.3 107.7 28.7 34.4 22.3 18.0 23.6 37.7 10.0 12.0 19.0 10.7 36.4 20.8 27.7 13.6 10.3 12.5 28.6 37.2 16.0 14.2 18.2 19.7 173.0 21.1 22.0 17.8 37.5 15.1 22.4 15.5 45.8 67.1 15.7 21.8 17.7 24.5 21.2 14.8 7.3 27.2 84.5 6.6 30.0 21.9 81.7 38.0 18.7 21.9 15.2 21.4 30.8 15.8 21.3 TMC2 "C20orf145, dJ686C3.3" ENSG00000149488 "Transmembrane channel like 2" Q8TDI7 20 2536573-2643580 "Predicted membrane proteins" "Ion transport, Transport" "Ion channel" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "lung: 1.1;pituitary gland: 1.8" "Group enriched" "Detected in some" 6 "Late spermatids: 11.4;Oligodendrocyte precursor cells: 32.6" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 2: Immune cells - Immune response" "Cluster 68: Oligodendrocytes - Mixed function" "unprognostic (4.73e-2)" "unprognostic (1.87e-1)" "unprognostic (5.88e-2)" "unprognostic (8.30e-4)" "unprognostic (2.86e-3)" "unprognostic (3.00e-1)" "unprognostic (1.13e-2)" "unprognostic (1.07e-2)" "unprognostic (4.54e-1)" "unprognostic (1.41e-2)" "unprognostic (4.05e-5)" "unprognostic (2.90e-1)" "unprognostic (3.21e-7)" "unprognostic (2.47e-2)" "unprognostic (2.56e-1)" "unprognostic (1.93e-1)" "unprognostic (5.74e-2)" 0.8 0.1 0.2 0.1 0.2 0.1 0.5 1.0 0.2 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.2 0.4 0.0 0.2 0.3 0.0 0.0 1.1 0.1 0.1 0.0 0.2 0.2 0.0 1.8 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.1 0.3 0.1 0.0 0.0 0.1 0.0 0.5 0.2 0.0 0.1 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.1 0.1 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.2 1.0 0.2 0.2 0.3 0.1 0.0 0.1 0.0 0.2 0.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 11.4 0.0 0.0 0.0 1.9 0.0 0.0 0.0 32.6 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 TMCC2 "FLJ38497, HUCEP11" ENSG00000133069 "Transmembrane and coiled-coil domain family 2" O75069 1 205227946-205285632 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 88.1;brain: 47.3" "Cell type enriched" "Detected in many" 8 "Erythroid cells: 622.1" "Cancer enhanced" "Detected in many" "melanoma: 10.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SCLC-21H: 32.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014254 Approved NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 6: Erythroid cells - Oxygen transport" "HPA014254: AB_1851326" "unprognostic (2.59e-1)" "unprognostic (1.28e-1)" "unprognostic (1.13e-2)" "unprognostic (2.61e-2)" "unprognostic (4.18e-1)" "unprognostic (5.59e-2)" "unprognostic (2.46e-2)" "unprognostic (4.89e-2)" "unprognostic (2.53e-1)" "unprognostic (5.08e-2)" "unprognostic (1.05e-5)" "unprognostic (3.17e-1)" "unprognostic (1.39e-1)" "unprognostic (1.99e-3)" "unprognostic (3.06e-2)" "unprognostic (4.01e-1)" "unprognostic (3.43e-3)" 1.4 2.6 15.2 0.4 24.2 88.1 0.9 18.7 47.3 1.8 0.0 2.5 0.3 1.6 0.0 0.7 2.0 0.3 3.6 25.2 16.1 1.4 0.7 3.1 0.3 38.5 26.1 3.1 0.5 3.1 5.0 5.3 41.0 1.0 0.1 8.5 0.9 0.3 3.5 1.7 0.9 0.5 17.3 16.0 0.9 2.0 25.5 0.7 1.3 1.5 0.2 1.2 1.6 33.6 1.9 0.9 1.7 3.8 0.7 0.2 0.9 2.4 1.0 2.3 1.8 0.3 0.2 1.8 0.4 0.6 6.3 3.2 1.1 0.5 0.7 5.7 4.2 7.5 0.5 0.1 0.3 0.3 3.5 0.4 0.1 1.2 0.0 2.0 0.3 1.7 4.0 2.4 0.9 0.1 0.0 0.9 4.1 0.0 5.2 2.8 4.3 9.1 0.4 0.1 32.0 4.3 0.2 0.0 8.0 1.5 0.7 0.4 0.8 1.5 2.5 3.9 2.7 4.9 2.1 1.2 1.3 0.6 9.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.4 15.2 24.2 18.7 47.3 25.2 16.1 38.5 26.1 41.0 17.3 25.5 33.6 1.9 0.0 0.0 6.2 0.4 1.0 0.4 1.2 0.0 34.4 0.2 0.0 4.6 0.0 0.3 1.8 10.4 0.1 0.3 0.0 0.0 1.6 1.5 3.7 0.8 2.5 3.5 622.1 7.9 0.0 0.2 1.0 0.0 1.9 0.0 7.4 3.9 0.0 0.9 40.4 10.1 0.1 0.0 0.6 6.1 0.8 1.2 13.1 3.6 2.8 7.8 17.7 0.0 2.5 73.0 0.2 0.0 0.4 0.8 0.1 0.0 0.2 0.9 43.2 0.0 1.8 2.8 1.1 4.8 0.4 0.9 0.0 0.7 0.8 0.1 0.1 TMED1 "Il1rl1l, IL1RL1LG, MGC1270, p24g1, p24gamma1, ST2L" ENSG00000099203 "Transmembrane p24 trafficking protein 1" Q13445 19 10832067-10836318 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 146.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018507 Uncertain NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 38: EFO-21 - Unknown function" "Cluster 55: Plasma cells - Humoral immune response" "HPA018507: AB_1858063" "unprognostic (6.98e-2)" "unprognostic (3.42e-1)" "unprognostic (3.03e-3)" "unprognostic (1.28e-1)" "unprognostic (8.65e-2)" "unprognostic (2.27e-1)" "unprognostic (1.98e-2)" "unprognostic (4.20e-2)" "unprognostic (9.86e-2)" "unprognostic (7.27e-2)" "unprognostic (9.52e-2)" "unprognostic (4.93e-2)" "prognostic favorable (8.66e-5)" "unprognostic (9.49e-2)" "unprognostic (2.56e-1)" "unprognostic (5.16e-2)" "unprognostic (2.45e-2)" 23.6 31.2 13.4 15.4 15.3 21.6 25.1 15.6 17.3 30.0 24.9 19.5 18.9 25.0 16.3 19.9 24.8 18.8 42.3 13.0 16.9 37.8 51.9 19.6 14.3 16.6 15.1 34.4 34.5 24.4 35.9 21.4 15.5 26.5 8.1 4.4 24.2 14.8 64.4 19.1 17.4 10.6 15.2 22.3 26.2 20.2 14.5 10.2 28.7 34.9 7.0 22.3 21.0 17.4 40.4 63.3 26.7 43.6 26.2 28.5 27.8 63.3 53.0 59.0 82.3 59.2 57.2 29.1 146.5 46.0 30.8 32.2 18.8 33.4 23.6 44.2 38.5 41.5 49.8 48.5 35.4 35.2 91.4 42.2 35.1 34.9 24.9 25.8 37.4 22.3 30.3 80.6 25.3 63.9 25.4 38.0 41.3 23.6 60.5 27.8 22.9 44.6 35.0 33.3 29.5 29.0 37.6 37.0 33.9 11.2 43.8 38.5 41.5 75.1 34.4 80.3 71.6 48.9 56.6 27.8 58.1 63.5 41.6 12.3 94.6 44.3 59.3 94.0 40.9 50.9 39.9 48.6 81.1 42.2 36.6 40.5 35.7 122.8 103.0 59.9 38.9 66.0 13.4 15.3 15.6 17.3 13.0 16.9 16.6 15.1 15.5 15.2 14.5 17.4 20.2 9.6 15.3 4.6 16.5 18.5 24.4 53.9 12.0 10.2 31.8 32.0 0.2 41.5 33.0 53.3 8.4 111.5 24.5 22.7 41.1 54.4 5.5 30.9 26.7 26.4 23.5 30.7 1.0 44.2 94.0 38.1 15.8 21.7 27.3 43.7 24.3 43.9 52.5 5.0 1.2 21.1 46.8 20.2 16.6 6.3 22.4 20.0 42.7 1.0 25.0 40.3 28.8 4.0 3.2 41.7 35.5 20.3 24.4 35.4 37.7 57.4 42.9 18.0 32.9 28.9 27.1 21.7 30.9 14.8 17.5 146.3 15.1 62.3 28.8 23.3 TMEM106A MGC20235 ENSG00000184988 "Transmembrane protein 106A" Q96A25 17 43211835-43220041 "Predicted membrane proteins, Transporters" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 21.9" "Cell type enhanced" "Detected in many" "Granulosa cells: 45.6;Hofbauer cells: 45.3;Kupffer cells: 44.8;Langerhans cells: 35.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 26.7" "Lineage enriched" "Detected in all" 4 "granulocytes: 26.7" "Cell line enhanced" "Detected in many" "HMC-1: 16.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 40: Granulosa cells - Unknown function" "unprognostic (9.71e-2)" "unprognostic (2.61e-1)" "prognostic unfavorable (9.61e-5)" "unprognostic (4.95e-3)" "unprognostic (8.62e-2)" "unprognostic (1.79e-1)" "unprognostic (9.11e-2)" "unprognostic (1.76e-1)" "unprognostic (5.77e-2)" "unprognostic (2.01e-1)" "unprognostic (2.99e-2)" "unprognostic (6.08e-2)" "unprognostic (7.89e-3)" "unprognostic (1.39e-1)" "unprognostic (5.34e-2)" "unprognostic (1.24e-1)" "unprognostic (8.30e-2)" 4.9 2.4 1.7 10.2 2.1 3.3 4.1 1.2 2.9 3.8 2.4 3.6 4.0 3.6 1.7 1.5 3.3 3.6 2.1 1.6 2.5 21.9 3.5 5.2 6.9 6.2 3.0 7.8 3.1 2.4 1.6 10.1 3.8 2.5 5.3 0.8 2.8 3.1 1.1 1.3 3.4 8.8 2.8 9.7 4.8 3.3 6.1 4.0 5.3 1.5 6.1 4.8 2.4 4.1 3.1 0.9 0.4 0.2 3.8 4.1 2.3 7.8 5.0 6.7 10.5 2.3 6.4 4.5 1.5 12.1 2.6 1.3 0.8 1.0 7.8 7.1 0.0 3.2 2.7 10.7 2.2 0.1 16.8 2.6 0.2 12.5 0.3 2.4 6.0 5.3 0.1 3.2 8.5 1.3 5.5 2.1 0.3 0.0 0.0 4.0 1.3 2.7 2.9 0.2 0.6 0.0 1.5 3.7 1.8 1.6 5.5 4.5 6.8 3.3 0.4 3.3 1.6 5.0 0.5 1.4 2.8 5.4 6.7 26.7 5.1 5.7 1.5 5.6 0.7 1.9 1.0 1.5 4.2 3.2 0.7 1.3 1.4 2.1 2.0 6.0 2.9 2.2 1.7 2.1 1.2 2.9 1.6 2.5 6.2 3.0 3.8 2.8 6.1 4.1 4.5 3.2 4.5 1.3 13.6 2.4 11.0 2.4 0.6 4.3 6.5 4.2 1.2 0.0 3.9 7.3 2.1 5.0 22.7 3.9 3.9 2.0 5.9 2.6 7.1 6.5 3.0 2.5 1.0 4.0 8.3 6.6 10.7 3.9 8.2 45.6 5.0 1.7 45.3 0.0 1.0 4.5 0.0 44.8 35.6 2.7 14.0 25.2 0.0 17.8 16.5 1.2 14.4 3.5 4.0 5.5 3.4 7.2 5.4 10.9 2.1 17.8 6.0 3.7 13.1 4.0 4.6 7.4 3.6 0.5 1.7 5.2 7.3 3.2 2.9 13.1 TMEM119 OBIF ENSG00000183160 "Transmembrane protein 119" Q4V9L6 12 108589851-108598320 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Biomineralization, Differentiation, Osteogenesis, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Early spermatids: 8.3;Fibroblasts: 30.5;Late spermatids: 9.3;Melanocytes: 8.8;Microglial cells: 15.0;Peritubular cells: 24.0;Smooth muscle cells: 9.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "ASC diff: 559.2;ASC TERT1: 152.6;BJ hTERT+: 168.0;fHDF/TERT166: 81.9;HSkMC: 238.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051870, HPA052650" Enhanced NA NA "Cluster 6: Non-specific - Transcription" "Cluster 28: Placenta - Pregnancy" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA051870: AB_2681645, HPA052650: AB_2681901" "unprognostic (4.90e-2)" "unprognostic (2.66e-1)" "unprognostic (6.84e-2)" "unprognostic (5.97e-2)" "unprognostic (2.35e-1)" "unprognostic (3.29e-2)" "unprognostic (6.67e-2)" "unprognostic (8.40e-2)" "unprognostic (1.51e-1)" "prognostic unfavorable (8.37e-4)" "unprognostic (1.61e-1)" "unprognostic (1.56e-1)" "prognostic unfavorable (2.06e-6)" "unprognostic (1.29e-2)" "unprognostic (8.76e-3)" "unprognostic (1.40e-2)" "unprognostic (1.87e-2)" 29.6 8.0 7.6 16.2 8.9 3.0 27.1 8.5 9.2 61.0 5.3 12.6 15.1 18.9 14.1 6.9 11.9 35.8 9.4 7.7 9.3 6.0 0.9 37.6 47.8 17.2 12.1 1.4 7.5 5.6 6.1 6.6 14.9 12.7 15.1 0.9 6.8 26.0 1.6 13.9 23.1 11.2 13.4 11.4 10.5 5.9 16.4 5.1 21.7 1.7 27.2 32.2 18.4 21.9 0.1 0.3 1.3 0.7 559.2 152.6 0.8 11.8 168.0 0.4 3.0 0.2 0.6 0.3 0.4 81.9 0.3 0.2 0.1 0.2 0.1 0.5 0.0 0.3 0.6 1.0 7.2 0.3 1.2 238.4 0.3 7.0 0.1 0.7 0.1 0.2 0.5 0.5 0.5 0.7 0.3 1.6 0.1 0.0 0.9 0.6 0.9 0.8 0.1 0.7 0.2 39.5 0.0 0.3 0.3 4.5 0.2 1.8 1.2 13.1 0.4 11.2 0.5 2.6 3.1 0.6 6.8 0.5 0.1 1.4 0.2 0.3 0.2 0.1 0.2 0.2 0.4 0.2 0.1 0.4 0.3 0.3 1.4 0.2 0.4 0.2 0.1 0.1 7.6 8.9 8.5 9.2 7.7 9.3 17.2 12.1 14.9 13.4 16.4 21.9 1.3 0.0 0.0 0.0 0.2 3.8 0.1 0.0 0.6 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.0 0.3 1.5 0.0 0.0 0.0 8.3 0.2 5.8 1.3 0.0 0.0 0.0 0.0 0.2 30.5 0.0 0.2 0.0 0.0 0.7 0.0 1.4 0.0 0.0 0.0 0.0 1.9 4.4 9.3 4.1 1.1 8.8 15.0 1.6 0.0 0.0 0.0 0.0 0.1 1.1 24.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.8 9.7 0.1 0.1 0.0 3.7 0.3 0.7 0.5 0.0 0.1 TMEM121B CECR6 ENSG00000183307 "Transmembrane protein 121B" Q9BXQ6 22 17116297-17121367 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.7;prostate: 6.6" "Cell type enhanced" "Detected in some" "granulocytes: 1.3;Hofbauer cells: 2.8" "Cancer enhanced" "Detected in some" "prostate cancer: 6.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.1;neutrophil: 1.6" "Group enriched" "Detected in many" 7 "granulocytes: 1.6;monocytes: 1.1" "Cell line enhanced" "Detected in some" "AF22: 6.0;SCLC-21H: 14.2;THP-1: 11.9;U-937: 9.8" "Low region specificity" "Detected in all" HPA068790 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 10: Brain - Neuronal signaling" "Cluster 43: THP-1 - Innate immune response" "Cluster 52: Non-specific - Transcription" Vesicles "Nucleoplasm, Plasma membrane" "HPA068790: AB_2686036" "unprognostic (2.30e-1)" "unprognostic (1.05e-1)" "unprognostic (7.11e-3)" "unprognostic (4.49e-3)" "unprognostic (3.36e-1)" "unprognostic (7.14e-3)" "unprognostic (1.12e-3)" "unprognostic (5.32e-2)" "unprognostic (1.97e-1)" "unprognostic (2.01e-2)" "unprognostic (6.88e-4)" "unprognostic (6.08e-2)" "unprognostic (3.10e-4)" "unprognostic (1.02e-2)" "unprognostic (4.37e-2)" "unprognostic (3.49e-3)" "unprognostic (1.71e-1)" 0.3 0.6 6.4 0.9 7.5 1.0 0.7 3.5 7.6 0.2 1.5 0.2 0.2 0.3 0.9 0.3 0.3 0.2 1.2 8.7 3.9 0.3 0.1 0.3 0.1 3.8 3.3 0.2 1.1 0.1 1.6 0.7 3.3 6.6 0.2 1.3 0.4 0.2 1.3 0.5 0.2 0.3 3.6 0.7 0.2 1.9 4.9 0.1 0.1 0.4 0.1 0.3 0.2 5.1 0.0 0.0 6.0 0.8 0.0 0.0 0.0 0.1 0.1 0.2 0.4 0.2 0.0 0.2 0.1 0.0 0.2 0.0 0.7 0.0 0.2 0.1 0.9 0.0 0.0 0.0 0.0 0.7 0.4 0.0 0.1 0.0 0.0 0.0 0.0 2.1 0.1 0.1 0.3 0.0 0.8 3.2 2.1 0.0 0.1 0.2 3.0 0.0 0.3 0.1 14.2 2.1 0.0 0.0 0.3 0.8 0.0 11.9 0.6 0.6 0.2 0.2 0.0 0.2 0.4 0.9 0.0 9.8 0.3 0.0 1.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.2 6.4 7.5 3.5 7.6 8.7 3.9 3.8 3.3 3.3 3.6 4.9 5.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.4 1.3 0.9 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 TMEM135 FLJ22104 ENSG00000166575 "Transmembrane protein 135" Q86UB9 11 87037844-87328824 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 121.8;Excitatory neurons: 99.6;Inhibitory neurons: 93.7;Oligodendrocyte precursor cells: 123.1;Oligodendrocytes: 202.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 88.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056685, HPA069473" Uncertain Supported Vesicles NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA056685: AB_2683208, HPA069473: AB_2686139" "unprognostic (1.55e-2)" "unprognostic (1.11e-1)" "unprognostic (2.70e-2)" "unprognostic (6.51e-2)" "unprognostic (3.10e-2)" "unprognostic (4.42e-1)" "unprognostic (1.45e-2)" "unprognostic (2.63e-1)" "unprognostic (2.19e-1)" "unprognostic (1.13e-1)" "unprognostic (2.26e-1)" "unprognostic (1.65e-1)" "prognostic favorable (9.02e-4)" "unprognostic (3.48e-2)" "unprognostic (7.34e-2)" "unprognostic (1.35e-2)" "unprognostic (1.80e-1)" 26.1 14.9 4.2 5.6 6.0 3.7 14.2 2.8 5.2 5.6 5.8 10.5 15.6 6.4 4.7 4.4 6.0 8.3 6.7 4.9 5.2 12.0 24.7 6.5 5.9 5.0 5.8 7.3 6.2 9.4 5.4 10.2 5.6 10.7 8.5 7.0 10.0 6.4 8.4 3.9 14.5 6.9 2.5 5.8 7.4 10.2 4.3 6.6 10.1 7.5 4.8 5.5 4.4 6.7 8.8 15.7 9.8 13.7 31.3 28.6 9.2 6.5 16.7 7.6 17.0 27.1 39.9 24.2 17.1 8.9 19.9 8.3 13.3 14.9 8.5 22.7 7.5 18.5 14.0 88.5 17.6 10.8 9.2 34.8 9.2 11.0 7.6 10.2 19.5 26.4 19.3 35.9 9.0 5.9 28.3 10.8 11.5 47.2 11.7 12.5 7.5 19.2 17.5 28.1 4.8 11.0 9.6 30.0 13.6 18.8 42.0 9.6 10.3 7.9 10.3 30.6 4.6 13.4 28.2 28.2 6.0 11.5 15.7 0.9 4.8 1.4 7.5 5.1 6.7 4.7 4.7 8.1 5.6 3.4 5.3 5.1 1.5 7.2 2.2 5.7 5.4 4.1 4.2 6.0 2.8 5.2 4.9 5.2 5.0 5.8 5.6 2.5 4.3 6.7 14.4 9.6 7.5 121.8 7.1 4.2 4.0 4.6 8.6 5.6 12.7 7.1 6.3 5.7 6.8 1.8 4.2 2.6 7.7 10.5 5.9 2.8 2.8 5.8 11.0 8.1 3.6 3.8 99.6 3.2 8.6 11.0 8.6 4.2 9.5 11.5 7.9 16.2 4.9 1.7 93.7 6.8 10.2 7.8 6.0 7.7 7.2 5.4 5.4 48.7 4.1 5.0 9.2 123.1 202.4 3.1 10.9 7.2 10.3 6.1 21.8 10.6 8.7 4.2 32.9 5.7 8.4 2.2 3.8 4.8 4.8 1.5 8.3 24.6 8.7 3.8 TMEM177 MGC10993 ENSG00000144120 "Transmembrane protein 177" Q53S58 2 119679167-119686507 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 66.5;Proximal tubular cells: 47.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036689, HPA053816" Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Nucleoli fibrillar center" "HPA036689: AB_2675253, HPA053816: AB_2682272" "unprognostic (1.24e-1)" "unprognostic (2.65e-1)" "unprognostic (1.62e-2)" "unprognostic (2.31e-2)" "unprognostic (9.81e-3)" "unprognostic (2.05e-3)" "unprognostic (3.17e-2)" "unprognostic (8.05e-2)" "unprognostic (1.39e-1)" "unprognostic (3.03e-2)" "unprognostic (1.07e-1)" "unprognostic (4.90e-1)" "unprognostic (6.73e-2)" "unprognostic (5.29e-2)" "unprognostic (2.48e-1)" "unprognostic (1.58e-1)" "unprognostic (1.02e-1)" 3.2 8.0 6.6 4.8 7.1 1.0 6.8 7.4 7.7 5.3 3.3 10.9 16.1 6.6 9.0 5.7 10.6 3.9 8.2 6.8 4.6 13.4 25.7 3.3 5.1 4.2 6.2 7.9 5.5 8.2 12.5 3.2 4.5 5.9 9.1 7.2 6.9 5.9 12.2 6.7 13.7 5.2 3.9 4.0 6.3 7.7 6.6 4.7 5.6 7.0 5.2 5.2 4.9 6.6 22.9 19.9 17.2 16.7 4.6 4.5 8.9 8.4 10.4 24.3 18.3 50.4 12.6 37.9 20.1 7.4 19.9 13.7 27.9 28.7 14.0 18.0 51.4 19.5 11.8 56.7 10.1 12.5 13.9 12.4 20.1 19.2 12.5 9.3 15.7 22.3 30.7 4.9 13.3 19.0 21.8 24.3 44.0 16.7 29.2 19.6 16.8 22.4 24.4 11.8 33.8 19.3 10.9 23.2 26.9 15.9 17.7 21.1 12.8 12.0 28.7 9.2 16.7 4.9 3.8 23.3 4.5 15.2 22.0 0.0 2.6 2.6 8.2 2.1 8.5 6.6 6.9 8.4 4.9 8.7 16.2 10.3 0.8 7.2 1.4 5.8 7.9 5.5 6.6 7.1 7.4 7.7 6.8 4.6 4.2 6.2 4.5 3.9 6.6 6.6 2.6 3.2 0.0 3.3 3.6 2.9 12.1 13.9 1.8 13.3 8.2 9.7 13.0 11.5 10.7 5.5 14.6 11.9 2.1 8.9 66.5 16.0 2.2 4.0 6.8 5.0 2.4 3.4 4.1 14.3 9.7 5.4 5.6 2.8 0.0 10.1 1.4 30.5 6.3 11.8 4.1 7.2 8.2 1.2 1.1 2.1 7.5 1.5 14.2 0.0 4.7 9.4 5.2 5.5 2.0 12.3 6.5 12.4 3.4 9.2 22.8 47.2 5.4 21.8 0.0 2.6 6.1 6.5 6.6 5.1 2.0 2.1 4.1 21.5 14.1 4.5 TMEM179B ENSG00000185475 "Transmembrane protein 179B" Q7Z7N9 11 62787402-62790400 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016585, HPA062068" Enhanced "Nuclear speckles" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nuclear speckles" "HPA016585: AB_1844357, HPA062068: AB_2684676" "unprognostic (1.18e-2)" "unprognostic (2.83e-1)" "unprognostic (2.20e-1)" "unprognostic (1.78e-2)" "unprognostic (1.68e-1)" "unprognostic (6.11e-3)" "unprognostic (1.96e-2)" "unprognostic (2.35e-1)" "unprognostic (2.44e-1)" "unprognostic (1.25e-2)" "unprognostic (4.61e-3)" "unprognostic (2.76e-2)" "unprognostic (4.56e-1)" "unprognostic (1.64e-1)" "unprognostic (2.16e-1)" "unprognostic (5.74e-3)" "unprognostic (3.60e-2)" 52.1 60.3 32.4 22.0 34.7 21.5 55.0 33.7 36.4 50.5 41.8 48.7 34.7 44.4 71.2 47.9 46.7 28.4 34.0 30.8 32.9 54.3 64.3 51.0 26.9 35.3 33.3 39.6 58.7 34.1 31.0 30.0 35.6 45.8 40.1 10.4 59.1 26.4 27.2 58.2 49.8 26.3 33.7 48.1 53.9 41.6 33.0 33.0 55.4 21.6 29.8 43.3 46.0 36.9 35.6 68.8 17.7 35.7 136.3 34.3 22.6 38.2 47.5 29.8 34.2 39.3 82.9 16.5 53.1 78.0 44.2 64.8 33.4 35.4 23.2 48.6 44.9 24.1 29.2 36.3 90.8 30.9 32.2 65.8 55.8 57.1 70.0 60.0 30.3 46.9 33.2 46.3 34.5 81.1 40.2 59.5 26.5 76.8 74.6 26.5 28.8 86.1 57.7 42.6 24.4 26.7 49.3 65.3 70.4 35.8 76.2 37.8 42.2 39.6 29.4 73.3 32.2 51.2 32.5 22.6 57.0 19.0 47.3 302.9 300.4 332.7 149.4 305.0 147.9 169.2 135.5 144.9 198.2 140.6 118.2 117.3 224.3 140.2 305.9 366.1 146.6 282.5 32.4 34.7 33.7 36.4 30.8 32.9 35.3 33.3 35.6 33.7 33.0 36.9 119.6 60.9 59.2 15.3 52.7 68.7 73.9 175.6 86.0 12.4 108.0 122.2 1.3 65.8 121.1 60.7 0.0 174.5 71.7 91.2 37.2 138.1 5.8 75.2 54.5 83.7 65.2 40.4 9.9 149.0 160.5 76.8 54.6 66.5 54.6 43.8 69.9 81.9 133.2 8.4 9.0 103.5 128.1 63.7 83.0 11.0 75.8 76.5 106.7 12.2 98.3 74.4 91.6 16.1 28.1 124.0 137.1 45.9 93.9 97.1 179.4 87.5 122.9 14.7 65.7 50.5 57.8 120.8 100.5 93.2 76.0 185.1 60.0 90.4 94.8 97.5 TMEM183A C1orf37 ENSG00000163444 "Transmembrane protein 183A" Q8IXX5 1 203007374-203024848 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072607 Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Plasma membrane" "Nucleoplasm, Cell Junctions" "HPA072607: AB_2686539" "unprognostic (2.94e-3)" "unprognostic (1.60e-1)" "unprognostic (1.30e-1)" "unprognostic (1.33e-1)" "unprognostic (3.41e-2)" "unprognostic (5.99e-2)" "prognostic unfavorable (2.62e-4)" "unprognostic (6.46e-2)" "unprognostic (3.21e-2)" "unprognostic (4.82e-3)" "unprognostic (5.28e-2)" "unprognostic (7.84e-2)" "unprognostic (4.83e-2)" "unprognostic (6.01e-3)" "unprognostic (9.55e-2)" "unprognostic (3.65e-2)" "unprognostic (1.32e-1)" 21.6 19.1 27.6 17.0 28.8 76.6 22.1 28.2 35.1 22.9 23.8 30.9 26.6 19.8 18.8 30.3 19.4 14.1 17.0 30.1 30.1 22.8 23.9 21.0 21.7 26.7 25.8 20.1 28.7 17.8 12.2 14.4 27.7 21.2 30.2 21.8 25.4 16.4 14.8 27.5 26.1 19.9 23.7 22.2 25.2 34.1 26.7 30.0 22.2 12.7 24.1 23.4 22.9 27.0 32.7 31.2 39.2 64.6 50.6 37.7 64.4 32.2 31.7 36.4 31.7 38.1 33.6 81.1 22.6 41.7 14.6 40.4 53.1 45.1 30.1 26.6 64.5 40.2 33.8 42.3 36.6 72.6 33.9 37.3 49.3 30.1 60.2 36.8 46.6 64.4 83.8 28.7 34.5 73.3 59.7 74.4 107.7 44.0 49.2 45.4 66.7 65.7 57.0 31.6 50.2 62.7 48.0 79.0 48.1 61.9 56.6 56.6 34.8 24.4 34.2 42.3 35.7 28.8 49.7 62.4 27.0 55.7 26.3 33.3 33.6 51.2 23.5 29.2 23.1 23.8 26.3 26.6 37.4 26.2 29.8 24.7 28.7 36.6 27.8 26.8 30.6 37.4 27.6 28.8 28.2 35.1 30.1 30.1 26.7 25.8 27.7 23.7 26.7 27.0 39.7 16.0 20.5 3.6 40.4 73.4 61.5 62.2 41.5 22.8 62.2 48.6 14.9 54.3 52.1 35.0 10.4 53.2 57.3 70.4 70.5 88.6 161.1 31.1 34.9 36.2 52.7 103.7 13.2 76.1 86.0 34.8 42.3 34.4 17.7 34.6 40.7 53.6 60.4 18.5 11.8 87.5 63.1 63.1 52.0 113.7 27.1 49.7 39.2 6.5 71.1 26.6 50.4 3.5 7.2 52.7 57.6 29.3 62.1 100.2 102.3 100.4 44.5 28.0 19.7 38.3 46.7 95.0 80.9 72.9 82.1 51.6 48.3 39.6 88.6 105.2 TMEM185A "CXorf13, FAM11A, FRAXF" ENSG00000269556 "Transmembrane protein 185A" Q8NFB2 X 149596556-149631912 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048295, HPA071744" Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 51: Myeloid cells - Hemostasis" "Endoplasmic reticulum" "HPA048295: AB_2680345, HPA071744: AB_2686441" "unprognostic (9.76e-2)" "unprognostic (2.83e-2)" "unprognostic (7.73e-2)" "unprognostic (2.71e-3)" "unprognostic (4.08e-1)" "unprognostic (1.97e-1)" "unprognostic (4.34e-3)" "unprognostic (1.71e-1)" "unprognostic (1.83e-1)" "unprognostic (1.92e-1)" "unprognostic (2.78e-2)" "unprognostic (2.69e-1)" "unprognostic (3.17e-1)" "unprognostic (1.37e-2)" "unprognostic (1.90e-1)" "unprognostic (1.07e-1)" "unprognostic (1.40e-1)" 15.0 13.8 5.7 8.0 6.6 6.8 13.1 6.8 9.0 14.6 19.7 12.9 7.1 15.0 17.3 15.5 14.4 11.3 30.1 6.7 6.4 10.6 8.9 9.9 10.7 6.0 6.1 30.9 9.5 16.4 8.1 26.8 6.1 13.9 9.4 10.6 12.9 16.8 13.6 20.0 9.1 16.6 6.4 16.8 9.7 17.0 6.9 10.7 9.9 15.9 11.0 12.8 15.1 6.1 18.0 17.7 20.0 12.4 27.0 17.8 8.2 16.9 20.8 16.6 24.2 10.9 29.9 21.4 37.7 19.0 22.8 22.1 23.1 16.4 17.0 14.3 17.3 12.1 19.6 11.8 19.9 18.5 12.8 17.4 27.6 16.9 10.8 19.8 14.6 16.6 5.1 13.1 12.4 29.5 13.1 13.6 14.9 9.5 19.8 12.1 29.8 12.3 20.1 22.8 6.9 9.9 12.5 21.2 23.1 17.9 11.7 10.4 17.6 13.5 11.8 24.7 21.9 12.7 12.0 30.8 22.6 21.9 18.6 2.2 5.1 12.9 9.9 3.1 8.4 5.2 6.9 10.0 7.5 5.0 9.5 8.9 7.1 14.9 2.7 5.6 9.6 6.4 5.7 6.6 6.8 9.0 6.7 6.4 6.0 6.1 6.1 6.4 6.9 6.1 13.5 6.4 2.6 5.9 7.6 11.1 12.1 19.8 6.2 17.4 13.5 12.1 12.3 2.8 9.8 14.7 6.2 29.1 13.1 9.6 3.9 4.4 0.6 22.6 10.5 12.1 13.1 6.5 12.1 9.3 10.7 15.4 2.0 11.2 5.7 22.7 23.9 7.2 11.2 18.5 12.3 5.9 18.3 11.7 12.0 3.2 22.7 11.4 14.2 6.5 16.1 12.2 17.5 10.6 8.2 12.7 9.3 23.7 4.1 8.6 8.3 6.8 17.5 9.2 46.0 9.4 14.1 11.7 16.8 11.0 20.0 17.2 9.8 24.3 5.1 17.7 TMEM186 "C16orf51, DKFZP564K2062" ENSG00000184857 "Transmembrane protein 186" Q96B77 16 8780384-8797642 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 44.8;Late spermatids: 106.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018226, HPA063559" Uncertain Approved "Cell Junctions" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" "Cell Junctions" "HPA018226: AB_1845579, HPA063559: AB_2685041" "unprognostic (3.49e-1)" "unprognostic (1.07e-2)" "unprognostic (1.11e-2)" "unprognostic (2.98e-2)" "unprognostic (4.81e-2)" "unprognostic (1.18e-1)" "unprognostic (2.32e-2)" "unprognostic (2.08e-2)" "unprognostic (8.06e-2)" "unprognostic (9.35e-2)" "unprognostic (2.45e-1)" "unprognostic (3.99e-2)" "prognostic favorable (1.93e-8)" "unprognostic (1.06e-1)" "unprognostic (3.73e-2)" "unprognostic (1.70e-1)" "unprognostic (3.89e-2)" 7.0 11.2 8.6 6.2 9.0 2.2 10.0 8.8 10.5 6.5 9.2 10.8 9.6 7.5 12.5 9.6 9.3 4.6 13.2 8.5 8.9 12.3 16.3 5.8 8.6 8.6 8.7 8.5 8.9 12.4 9.5 7.2 8.8 7.5 11.2 5.0 8.3 7.2 18.5 8.3 9.7 7.5 8.6 9.9 9.5 7.8 8.9 7.9 7.6 21.3 10.7 7.5 6.5 9.2 10.4 16.1 11.8 15.1 19.8 10.5 11.2 11.8 12.1 15.2 12.5 15.9 17.1 31.9 9.8 8.7 10.4 19.8 21.2 16.8 17.3 18.7 20.4 13.4 22.3 34.1 22.0 15.1 10.3 12.7 27.8 16.7 24.4 12.5 14.0 25.9 23.3 17.1 9.0 28.3 11.7 14.7 15.0 22.0 13.9 24.4 15.5 35.3 16.3 8.8 18.1 17.3 16.2 22.7 14.3 12.0 27.1 12.0 8.9 10.8 15.1 27.0 9.9 15.6 17.6 15.5 16.8 27.1 8.8 9.9 8.7 6.8 7.5 8.6 10.0 13.1 8.1 8.8 9.1 11.5 13.7 10.9 4.1 9.1 13.3 7.0 11.7 7.4 8.6 9.0 8.8 10.5 8.5 8.9 8.6 8.7 8.8 8.6 8.9 9.2 3.4 6.4 6.7 2.6 6.7 8.2 7.1 16.1 5.7 6.9 7.3 6.6 2.7 10.0 13.1 11.0 0.0 23.4 4.4 7.8 21.5 15.1 44.8 4.8 6.0 5.6 13.8 8.2 1.9 11.2 13.3 5.7 6.1 5.0 7.0 9.6 6.1 12.8 13.2 13.5 1.5 9.4 12.2 4.9 4.7 106.9 9.3 2.5 7.2 1.0 9.9 10.8 11.3 1.5 1.9 9.9 6.7 6.4 5.1 9.8 14.8 21.9 9.3 5.6 13.1 6.6 5.3 21.3 11.9 9.5 9.5 15.1 5.0 11.0 16.0 5.8 TMEM191C ENSG00000206140 "Transmembrane protein 191C" A6NGB0 22 21466423-21471269 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 36 "testis: 50.7" "Group enriched" "Detected in many" 19 "Early spermatids: 841.3;Late spermatids: 1024.5" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 3.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in single" "CACO-2: 1.0" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 83: Testis - Spermatogenesis" "Cluster 39: CACO-2 - Unknown function" "Cluster 34: Spermatids - Unknown function" "unprognostic (2.55e-1)" "unprognostic (2.18e-2)" "unprognostic (7.12e-3)" "unprognostic (2.83e-2)" "unprognostic (1.19e-1)" "unprognostic (1.86e-1)" "unprognostic (1.77e-2)" "unprognostic (5.97e-2)" "unprognostic (1.25e-1)" "unprognostic (2.40e-2)" "unprognostic (1.59e-3)" "unprognostic (2.09e-1)" "unprognostic (2.41e-1)" "unprognostic (1.78e-1)" "unprognostic (7.63e-2)" "unprognostic (1.36e-1)" "unprognostic (4.12e-3)" 0.3 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.6 0.4 0.0 0.4 0.0 0.1 0.0 1.4 0.3 0.0 0.2 0.0 0.1 0.8 0.6 0.4 0.0 0.0 0.1 0.2 0.2 0.0 1.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.1 0.7 0.3 0.0 0.0 0.8 0.3 50.7 0.0 0.0 0.8 0.0 0.0 0.1 0.6 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 1.9 0.7 0.0 0.1 2.4 0.6 0.2 0.2 0.6 0.2 0.9 1.4 0.3 0.4 0.4 3.4 0.2 0.2 0.6 0.0 0.0 0.1 0.6 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 1.3 0.0 2.3 0.7 9.3 5.0 1.6 5.6 5.2 3.3 4.4 6.7 0.7 4.3 2.4 5.5 2.1 48.2 8.3 21.5 0.0 2.8 841.3 5.3 0.5 1.9 10.2 0.8 2.6 0.2 22.5 2.3 9.7 2.0 7.0 0.8 1.1 4.2 10.1 13.5 2.4 8.7 4.1 8.4 8.0 1024.5 5.3 6.5 3.6 0.0 6.3 1.0 11.3 0.0 0.5 4.3 17.2 4.1 3.3 1.5 28.0 8.0 4.9 2.4 0.0 1.3 2.8 10.0 8.7 9.2 6.8 19.0 8.7 2.1 7.3 1.0 TMEM200B TTMB ENSG00000253304 "Transmembrane protein 200B" Q69YZ2 1 29119429-29123903 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 60.6" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 8.8;Fibroblasts: 6.1;Leydig cells: 12.8;Melanocytes: 8.8;Peritubular cells: 15.1;Sertoli cells: 6.6;Smooth muscle cells: 9.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 28.2;BJ hTERT+ SV40 Large T+: 26.7;BJ hTERT+ SV40 Large T+ RasG12V: 29.5;fHDF/TERT166: 29.0;HBF TERT88: 25.3" "Low region specificity" "Detected in all" HPA055254 Uncertain NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "HPA055254: AB_2682760" "unprognostic (2.55e-1)" "unprognostic (2.12e-2)" "unprognostic (8.25e-3)" "unprognostic (1.39e-1)" "unprognostic (4.71e-3)" "unprognostic (6.84e-2)" "unprognostic (1.91e-1)" "unprognostic (1.52e-2)" "unprognostic (6.25e-2)" "unprognostic (1.33e-1)" "unprognostic (6.27e-2)" "unprognostic (1.22e-1)" "unprognostic (4.24e-2)" "unprognostic (1.81e-2)" "unprognostic (2.70e-1)" "unprognostic (1.12e-1)" "unprognostic (7.16e-3)" 16.8 4.4 2.0 4.0 6.3 0.0 11.8 6.9 3.3 47.2 6.6 29.5 2.3 60.6 7.8 5.6 21.5 7.3 7.0 1.9 2.4 9.4 8.4 10.5 1.2 2.2 2.1 33.3 2.5 26.1 3.6 6.5 2.2 24.6 4.1 0.3 4.1 39.7 2.2 5.8 9.2 35.1 2.0 6.4 6.4 13.3 2.6 1.0 5.0 2.6 1.3 20.9 24.3 2.1 21.0 0.0 3.4 0.0 28.2 23.4 1.1 14.4 22.6 26.7 29.5 1.1 2.3 0.0 3.5 29.0 9.8 0.4 2.3 0.0 25.3 0.1 0.9 0.1 5.7 1.8 19.6 0.0 0.1 12.5 2.7 20.1 3.9 1.1 0.3 0.0 0.0 0.0 0.2 0.1 0.0 0.3 1.9 0.0 5.8 0.0 0.0 0.0 0.3 0.1 0.0 1.7 20.7 0.0 0.1 9.5 0.0 0.0 0.0 9.4 0.4 19.9 0.4 0.0 0.0 0.0 11.6 0.0 19.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 6.3 6.9 3.3 1.9 2.4 2.2 2.1 2.2 2.0 2.6 2.1 2.0 3.2 0.6 0.7 0.2 1.9 0.4 0.2 2.8 0.8 0.6 1.8 1.0 1.5 0.7 0.0 2.1 0.1 0.2 0.1 0.0 0.0 0.1 1.0 8.8 1.3 0.0 0.0 0.3 0.0 0.5 6.1 0.0 0.6 0.0 0.0 1.1 1.2 0.1 0.0 0.1 0.0 0.0 0.0 1.2 2.4 12.8 0.1 8.8 1.9 0.1 0.1 0.0 0.0 0.1 0.0 0.1 15.1 0.0 0.3 0.0 5.9 0.4 1.9 6.6 1.1 9.5 0.3 0.6 0.2 0.6 0.5 0.4 0.0 0.0 0.3 TMEM210 ENSG00000185863 "Transmembrane protein 210" A6NLX4 9 137170858-137172056 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "testis: 14.8" "Group enriched" "Detected in some" 68 "Early spermatids: 900.5;Late spermatids: 1815.1" "Cancer enhanced" "Detected in single" "prostate cancer: 1.2" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 33 "plasmacytoid DC: 3.2" "Lineage enriched" "Detected in single" 33 "dendritic cells: 3.2" "Cell line enriched" "Detected in some" 8 "RPMI-8226: 13.5" "Not detected" "Not detected" HPA066907 Enhanced NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 25: RPMI-8226 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "HPA066907: AB_2685747" "unprognostic (5.17e-2)" "unprognostic (5.04e-2)" "unprognostic (2.87e-5)" "unprognostic (4.18e-2)" "unprognostic (3.63e-2)" "unprognostic (3.14e-2)" "unprognostic (8.00e-2)" 0.0 0.0 0.1 0.0 0.3 0.0 0.3 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.0 1.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 13.5 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.1 0.3 0.3 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 1.6 1.3 0.0 0.0 0.1 0.0 0.0 0.0 8.1 0.0 0.0 0.0 900.5 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.7 1815.1 12.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 6.4 0.0 1.1 0.0 0.0 0.0 0.0 19.7 0.0 0.1 9.1 4.9 0.0 0.1 0.0 0.1 0.0 0.0 0.2 TMEM215 ENSG00000188133 "Transmembrane protein 215" Q68D42 9 32783540-32789201 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 6.9;retina: 18.3;testis: 3.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 572.0;Early spermatids: 129.9;Late spermatids: 302.1" "Cancer enriched" "Detected in single" 14 "thyroid cancer: 4.9" "Region enriched" "Detected in many" 4 "thalamus: 6.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "NTERA-2: 1.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA052804, HPA063207" Supported "Nucleoplasm,Endoplasmic reticulum,Vesicles" NA NA "Cluster 77: Retina - Visual perception" "Cluster 5: NTERA-2 - Transcription" "Cluster 56: Bipolar cells - Visual perception" Nucleoplasm "Endoplasmic reticulum, Vesicles" "HPA052804: AB_2681957, HPA063207: AB_2732697" "unprognostic (1.31e-2)" "unprognostic (4.57e-2)" "unprognostic (1.07e-1)" "unprognostic (2.92e-2)" "unprognostic (5.85e-2)" "unprognostic (4.38e-3)" "unprognostic (2.17e-3)" "unprognostic (2.82e-1)" "unprognostic (2.72e-1)" "unprognostic (2.64e-1)" "unprognostic (3.83e-2)" "unprognostic (1.23e-1)" "unprognostic (1.54e-1)" "unprognostic (2.32e-2)" 0.0 0.0 1.2 0.0 0.9 0.0 0.0 0.0 0.5 0.5 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.7 1.5 0.0 0.0 0.0 0.0 0.2 1.6 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 18.3 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 3.9 6.9 0.0 0.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.9 0.0 0.5 0.7 1.5 0.2 1.6 0.3 0.3 6.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 572.0 0.0 0.0 0.2 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 129.9 0.0 1.2 0.4 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 3.7 0.0 0.0 0.1 1.7 0.3 0.0 0.0 0.0 0.0 302.1 2.8 0.1 0.0 0.0 0.0 9.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 25.9 0.0 0.0 0.1 3.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TMEM217 "C6orf128, dJ355M6.2" ENSG00000172738 "Transmembrane protein 217" Q8N7C4 6 37212178-37258155 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 9.1" "Cell type enhanced" "Detected in many" "Early spermatids: 20.5;Exocrine glandular cells: 16.0;Pancreatic endocrine cells: 15.9;Spermatocytes: 55.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEL: 7.7;HUVEC TERT2: 6.4;TIME: 17.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045432, HPA071187" Approved Nucleoli,Cytosol NA NA "Cluster 43: Testis - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoli Cytosol "HPA045432: AB_2732519, HPA071187: AB_2732174" "unprognostic (7.78e-2)" "unprognostic (5.49e-2)" "unprognostic (2.22e-2)" "unprognostic (1.29e-2)" "unprognostic (7.79e-2)" "unprognostic (2.02e-1)" "unprognostic (6.77e-3)" "unprognostic (1.40e-2)" "unprognostic (3.51e-2)" "unprognostic (4.23e-4)" "unprognostic (8.22e-2)" "unprognostic (2.18e-1)" "unprognostic (5.62e-2)" "unprognostic (7.26e-2)" "unprognostic (1.33e-2)" "unprognostic (6.99e-2)" "unprognostic (1.59e-1)" 0.7 3.1 0.9 0.7 1.0 2.8 0.5 1.0 1.6 0.3 0.9 0.3 1.1 0.3 1.5 1.6 0.7 1.2 0.3 0.9 0.9 0.6 0.9 0.7 0.4 0.9 0.9 0.3 2.7 1.3 0.1 0.3 1.0 0.3 0.3 0.7 1.2 0.1 0.1 1.0 0.4 0.4 0.8 0.2 0.2 9.1 1.0 0.7 0.7 0.0 0.3 2.2 0.1 1.1 0.7 0.0 0.5 0.4 0.3 2.1 0.3 2.2 3.9 1.9 5.5 1.7 1.3 0.1 0.8 0.5 2.4 1.2 0.7 0.6 2.0 0.7 1.1 7.7 1.7 0.9 0.9 0.2 3.7 1.4 1.7 5.0 0.5 1.0 6.4 0.8 2.5 0.0 0.9 0.9 0.5 3.2 0.6 0.0 0.3 1.0 0.2 0.2 2.1 0.8 0.6 0.3 0.4 0.4 1.0 0.9 0.1 0.4 17.6 1.8 0.5 0.2 0.4 0.5 0.7 1.9 0.3 1.7 0.4 0.3 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.2 0.1 0.2 0.2 0.1 0.0 0.1 0.1 0.1 0.9 1.0 1.0 1.6 0.9 0.9 0.9 0.9 1.0 0.8 1.0 1.1 2.6 0.0 0.6 2.9 0.7 2.5 8.9 2.6 0.6 0.8 3.9 1.8 0.2 1.5 3.9 1.8 0.0 0.8 1.3 3.4 3.9 15.0 20.5 8.3 1.3 3.3 1.8 0.0 2.9 16.0 0.6 3.8 2.0 5.6 5.7 1.4 0.4 0.1 0.9 3.3 2.1 0.4 2.0 0.6 6.3 14.9 0.6 2.8 1.8 0.0 0.0 6.4 0.0 1.5 3.0 15.9 1.1 0.0 0.5 6.9 0.8 1.1 5.0 0.5 0.0 4.1 1.8 55.0 0.8 3.4 3.0 1.1 1.1 1.5 1.0 13.9 TMEM225B ENSG00000244219 "Transmembrane protein 225B" P0DP42 7 99598267-99611045 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 34 "testis: 137.0" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 3.0;Breast glandular cells: 3.0;Breast myoepithelial cells: 3.0;Exocrine glandular cells: 2.5;Granulosa cells: 2.9;Proximal tubular cells: 2.0;Theca cells: 5.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Karpas-707: 11.9;U-266/70: 6.6" "Low region specificity" "Detected in many" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 7: Non-specific - Mitochondria" "unprognostic (1.91e-3)" "unprognostic (5.04e-3)" "unprognostic (1.04e-1)" "unprognostic (1.27e-2)" "unprognostic (2.00e-1)" "unprognostic (1.95e-1)" "unprognostic (6.27e-3)" "unprognostic (2.75e-2)" "unprognostic (1.11e-1)" "unprognostic (2.58e-2)" "unprognostic (1.25e-1)" "unprognostic (7.08e-2)" "unprognostic (1.62e-1)" "unprognostic (4.00e-1)" "unprognostic (6.86e-2)" "unprognostic (1.17e-1)" "unprognostic (2.50e-1)" 3.5 2.0 2.3 0.2 2.6 0.3 3.1 2.2 4.0 2.3 1.9 1.2 0.3 1.9 3.5 1.4 2.4 1.0 0.7 2.3 2.6 3.5 0.7 1.4 0.6 2.7 2.4 1.5 1.3 2.5 2.9 1.3 2.5 2.2 0.5 0.7 1.7 1.4 0.8 3.9 1.2 0.8 2.5 1.2 1.1 137.0 2.5 1.8 2.5 0.0 1.1 1.5 2.0 2.9 1.1 1.5 0.8 0.2 3.8 1.0 0.0 0.5 2.6 1.4 1.6 0.1 0.9 1.2 0.0 0.0 0.5 0.1 0.4 0.0 2.9 3.8 0.6 0.2 0.0 0.3 1.2 0.9 0.8 0.3 0.5 0.1 2.3 5.1 0.0 1.9 0.6 11.9 0.6 0.0 2.0 4.6 0.1 0.0 0.0 0.7 1.1 1.7 0.4 0.1 0.5 1.1 0.3 0.0 0.4 0.6 0.0 0.6 0.0 0.5 1.7 3.7 0.2 6.6 1.6 2.3 0.6 1.4 1.1 0.0 0.0 1.3 0.6 0.1 1.1 1.0 0.8 0.4 0.5 2.2 0.8 1.4 0.3 1.3 0.2 1.4 0.6 0.6 2.3 2.6 2.2 4.0 2.3 2.6 2.7 2.4 2.5 2.5 2.5 2.9 0.5 0.0 3.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.0 3.0 0.0 0.0 0.6 0.0 0.0 1.2 0.8 0.0 0.0 1.1 0.0 0.5 0.8 0.1 0.0 0.0 0.0 2.5 0.4 1.0 0.0 0.5 1.3 2.9 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.6 0.2 5.4 0.0 0.0 TMEM229B "C14orf83, FLJ33387" ENSG00000198133 "Transmembrane protein 229B" Q8NBD8 14 67447084-67533739 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 14.6;Late spermatids: 25.7;NK-cells: 15.5;Oligodendrocyte precursor cells: 19.1" "Cancer enhanced" "Detected in all" "melanoma: 12.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 12.9;MCF7: 13.6;SK-MEL-30: 11.6;U-937: 34.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046562 Approved NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 70: Brain - Nervous system development" "Cluster 32: U-937 - Innate immune response" "Cluster 34: Spermatids - Unknown function" "HPA046562: AB_10960265" "prognostic favorable (5.38e-4)" "unprognostic (6.55e-2)" "unprognostic (1.23e-1)" "prognostic favorable (1.21e-5)" "unprognostic (7.37e-2)" "unprognostic (1.08e-1)" "unprognostic (1.09e-1)" "unprognostic (2.01e-1)" "unprognostic (2.01e-2)" "unprognostic (1.12e-1)" "unprognostic (2.76e-3)" "unprognostic (1.95e-2)" "unprognostic (5.18e-1)" "unprognostic (8.66e-2)" "unprognostic (1.22e-1)" "unprognostic (8.20e-2)" "prognostic favorable (1.79e-5)" 1.5 15.3 10.1 5.6 8.7 1.8 3.7 21.2 15.8 10.8 0.0 4.3 15.7 1.4 10.9 1.3 2.0 4.1 1.3 10.9 10.7 2.0 1.1 3.5 9.1 25.8 10.9 1.1 5.0 12.5 6.9 0.8 27.6 2.7 3.3 5.4 4.0 10.4 0.5 1.4 14.2 3.2 10.4 9.8 4.2 6.1 15.4 11.8 8.3 0.9 6.1 5.0 1.5 11.5 3.2 0.4 0.0 0.8 0.3 0.0 1.2 0.5 0.7 0.8 3.3 0.0 10.1 12.9 0.1 0.3 2.8 0.0 0.2 0.7 0.1 4.2 1.0 7.8 0.0 0.0 1.0 8.5 1.5 0.2 0.4 0.1 0.0 0.2 0.0 0.8 0.1 0.5 0.0 13.6 5.2 3.2 0.1 6.7 0.6 4.7 0.1 1.9 0.1 6.7 1.9 0.4 0.0 4.9 11.6 0.5 10.3 8.1 0.0 0.1 0.5 0.1 0.2 0.0 0.0 0.0 0.6 34.5 7.0 5.8 5.7 9.1 9.9 6.5 9.5 1.3 5.9 8.0 2.7 0.9 5.0 6.5 0.1 5.5 6.9 1.5 2.5 5.8 10.1 8.7 21.2 15.8 10.9 10.7 25.8 10.9 27.6 10.4 15.4 11.5 1.2 0.0 0.5 1.3 2.6 0.3 0.3 3.6 0.0 4.8 3.5 2.5 1.8 2.8 2.5 0.0 14.6 0.1 8.3 3.6 0.0 2.0 12.6 2.3 0.3 1.4 2.4 0.4 7.1 3.6 0.0 0.6 1.1 0.3 0.0 11.0 2.9 0.2 1.8 0.0 10.6 5.3 0.0 6.2 1.0 25.7 0.0 2.6 7.2 3.7 5.5 0.3 15.5 19.1 6.1 0.5 5.7 0.7 0.4 0.4 11.3 2.2 2.4 4.1 0.0 0.2 0.7 0.7 0.3 0.1 0.1 0.1 4.1 4.9 3.9 1.1 TMEM232 FLJ43080 ENSG00000186952 "Transmembrane protein 232" C9JQI7 5 110289233-110738956 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 14.4;testis: 16.9" "Cell type enhanced" "Detected in many" "Astrocytes: 154.8;Early spermatids: 130.7;Endometrial ciliated cells: 80.5;Excitatory neurons: 258.9;Inhibitory neurons: 175.0;Respiratory ciliated cells: 114.0;Spermatocytes: 83.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "U-266/70: 2.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA049386 Uncertain NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA049386: AB_2680739" "unprognostic (1.12e-2)" "unprognostic (1.43e-1)" "unprognostic (7.27e-2)" "unprognostic (1.47e-2)" "unprognostic (1.20e-1)" "unprognostic (4.40e-1)" "unprognostic (8.49e-2)" "unprognostic (9.88e-2)" "unprognostic (1.91e-1)" "unprognostic (1.22e-1)" "unprognostic (6.47e-3)" "unprognostic (1.65e-1)" "unprognostic (2.32e-5)" "unprognostic (1.02e-1)" "unprognostic (1.05e-1)" "unprognostic (3.14e-4)" "unprognostic (8.96e-2)" 0.6 1.2 2.7 0.2 2.4 0.1 1.1 1.1 1.8 1.1 8.3 0.4 0.5 0.8 1.7 0.6 14.4 1.8 0.7 1.8 2.3 3.7 0.7 1.7 0.4 6.6 7.9 0.7 0.4 2.1 1.3 0.4 6.0 0.9 0.4 3.6 0.6 0.7 0.0 0.4 0.3 0.4 5.1 0.2 0.9 16.9 2.8 0.4 3.8 0.3 0.3 0.3 0.1 5.3 0.4 0.1 1.0 0.3 0.8 1.5 0.2 0.0 0.0 0.2 0.2 0.2 0.1 0.5 0.3 0.0 1.6 0.3 0.2 0.8 0.2 1.0 0.1 0.1 0.0 0.0 0.7 0.3 0.1 0.4 0.1 0.2 0.4 1.4 0.0 1.2 0.3 0.3 0.5 0.1 0.5 0.3 0.1 0.1 0.0 0.2 0.1 0.2 1.0 0.0 0.8 1.0 0.1 0.0 0.9 1.6 0.4 0.1 0.0 1.1 0.1 0.0 0.0 2.5 0.9 0.4 0.7 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 2.4 1.1 1.8 1.8 2.3 6.6 7.9 6.0 5.1 2.8 5.3 0.6 0.0 5.4 154.8 0.4 0.4 0.9 4.8 1.2 5.0 1.2 0.8 2.4 1.5 11.7 7.3 27.1 0.3 0.0 0.4 9.8 1.3 130.7 80.5 1.4 0.7 1.2 0.8 258.9 0.5 0.1 0.8 0.0 2.3 0.0 0.7 1.1 0.6 0.1 3.3 175.0 0.6 8.2 1.3 0.0 68.0 1.2 0.7 0.0 32.8 0.0 4.5 0.0 54.8 66.1 0.2 0.1 0.7 0.5 0.7 0.4 5.5 114.0 16.9 0.0 1.6 1.8 83.9 4.3 0.1 0.4 0.3 0.2 1.6 0.3 0.6 TMEM269 ENSG00000274386 "Transmembrane protein 269" A0A1B0GVZ9 1 42785007-42816619 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "retina: 1.6" "Cell type enhanced" "Detected in single" "granulocytes: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "U-266/84: 2.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 16: U-266 - Nucleosome" "Cluster 60: Granulocytes - Receptor signaling" "unprognostic (2.03e-1)" "unprognostic (1.30e-1)" "unprognostic (2.87e-2)" "unprognostic (1.26e-1)" "unprognostic (5.97e-2)" "unprognostic (8.28e-2)" "unprognostic (6.27e-2)" "unprognostic (2.79e-1)" "unprognostic (1.00e-1)" "unprognostic (5.58e-2)" "unprognostic (8.51e-2)" "unprognostic (1.63e-1)" "unprognostic (4.01e-9)" "unprognostic (2.23e-1)" "unprognostic (2.85e-1)" "unprognostic (1.15e-1)" "unprognostic (4.77e-2)" 0.1 0.0 0.4 0.0 0.5 0.5 0.2 1.1 0.6 0.1 0.1 0.1 0.0 0.1 0.4 0.1 0.1 0.0 0.0 0.5 0.3 0.1 0.2 0.1 0.2 0.4 0.3 0.1 0.2 0.0 0.1 0.1 0.4 0.1 0.2 1.6 0.1 0.1 0.6 0.6 0.1 0.0 0.2 0.2 0.1 0.9 0.3 0.2 0.1 0.0 0.2 0.1 0.1 0.9 0.1 0.6 0.4 0.9 0.4 0.0 0.4 0.1 0.1 0.2 0.2 0.5 0.2 0.9 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.9 0.2 1.0 0.2 0.2 0.0 0.4 0.2 0.2 0.2 0.0 0.7 0.0 0.0 0.6 0.3 0.7 0.0 0.2 0.1 1.0 0.7 0.1 0.4 0.3 0.4 0.1 0.0 0.1 0.6 0.6 0.2 0.2 0.4 0.3 0.4 0.4 0.1 0.2 0.4 0.8 0.2 1.4 2.6 1.0 0.1 0.3 0.2 0.5 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.6 0.3 0.0 0.4 0.0 0.0 0.4 0.5 1.1 0.6 0.5 0.3 0.4 0.3 0.4 0.2 0.3 0.9 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.4 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 TMEM270 "MGC26719, WBSCR28" ENSG00000175877 "Transmembrane protein 270" Q6UE05 7 73861159-73865890 "Human disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 215 "testis: 77.6" "Cell type enriched" "Detected in single" 7 "Endometrial ciliated cells: 2.1" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "MCF7: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA077196 Approved Vesicles NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "HPA077196: AB_2732334" "unprognostic (3.84e-2)" "unprognostic (6.91e-2)" "unprognostic (6.87e-5)" "unprognostic (1.38e-2)" "unprognostic (1.11e-2)" "unprognostic (2.81e-3)" "unprognostic (1.34e-1)" "unprognostic (8.31e-3)" "unprognostic (2.07e-1)" "unprognostic (1.66e-1)" "unprognostic (4.69e-1)" "unprognostic (2.56e-2)" "unprognostic (3.35e-2)" "unprognostic (1.26e-1)" "unprognostic (1.44e-1)" "unprognostic (7.23e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 77.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.4 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.1 0.0 0.1 0.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TMEM31 MGC39655 ENSG00000179363 "Transmembrane protein 31" Q5JXX7 X 103710909-103714032 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 32 "testis: 110.1" "Cell type enriched" "Detected in some" 5 "Late spermatids: 3288.8" "Cancer enhanced" "Detected in some" "testis cancer: 1.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 1.8;BEWO: 4.3;MCF7: 6.4;NTERA-2: 1.8;U-937: 2.4" "Low region specificity" "Detected in all" HPA052760 Approved "Nucleoli fibrillar center" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoli fibrillar center" "HPA052760: " "unprognostic (9.42e-5)" "unprognostic (1.46e-2)" "unprognostic (1.18e-1)" "unprognostic (7.51e-2)" "unprognostic (7.75e-3)" "unprognostic (1.22e-2)" "unprognostic (2.43e-1)" "unprognostic (4.50e-2)" "unprognostic (1.06e-2)" "unprognostic (1.59e-1)" "unprognostic (1.39e-2)" "unprognostic (3.77e-1)" "unprognostic (5.91e-5)" "unprognostic (1.75e-2)" "unprognostic (1.12e-1)" "unprognostic (2.72e-1)" "unprognostic (4.68e-2)" 0.4 0.2 2.1 0.1 2.4 0.0 0.6 2.1 3.3 1.4 1.6 0.3 0.0 0.6 0.5 0.1 1.0 0.2 0.3 2.1 2.3 0.7 0.3 0.3 0.2 2.3 2.2 1.7 0.2 1.3 0.9 0.9 2.4 0.6 0.0 0.2 0.2 0.3 0.9 0.4 0.2 0.1 2.2 0.4 0.2 110.1 2.4 0.3 0.3 0.0 0.0 0.4 0.5 2.7 0.0 0.0 1.8 0.1 0.1 0.0 4.3 0.1 0.0 0.2 0.3 0.0 0.2 0.0 0.1 0.0 0.3 0.0 0.7 0.0 0.2 0.0 1.6 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.2 6.4 0.1 1.2 1.8 0.3 0.0 0.7 0.0 0.0 0.0 0.0 0.5 0.3 0.4 0.0 0.2 0.8 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.5 0.0 2.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.3 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 2.1 2.4 2.1 3.3 2.1 2.3 2.3 2.2 2.4 2.2 2.4 2.7 0.3 0.0 0.0 0.0 0.0 0.8 0.7 0.2 0.0 0.0 0.4 1.5 0.2 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.2 641.3 10.1 0.4 1.1 0.0 0.0 0.2 0.7 8.6 0.6 0.0 0.2 0.0 1.1 0.7 0.2 0.4 0.0 0.1 0.1 0.0 0.3 0.3 3288.8 13.4 1.2 0.0 0.0 0.0 0.0 0.0 0.5 0.7 0.1 0.0 7.5 0.0 0.3 0.0 0.2 0.0 0.0 13.1 0.3 0.3 19.6 12.1 0.0 0.3 2.9 0.0 0.2 0.0 0.2 TMEM72 "bA285G1.3, C10orf127, KSP37" ENSG00000187783 "Transmembrane protein 72" A0PK05 10 44911316-44937010 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "choroid plexus: 51.2;kidney: 74.4" "Cell type enhanced" "Detected in some" "Collecting duct cells: 27.6;Distal enterocytes: 21.1;Distal tubular cells: 33.2;Late spermatids: 15.9;Paneth cells: 8.9" "Cancer enriched" "Detected in some" 8 "renal cancer: 8.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 123 "RPMI-8226: 44.0;U-937: 26.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA039894, HPA062907" Enhanced NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA039894: AB_10795261, HPA062907: AB_2684900" "unprognostic (1.69e-1)" "unprognostic (1.10e-1)" "unprognostic (2.67e-2)" "unprognostic (3.22e-1)" "unprognostic (1.08e-1)" "unprognostic (4.57e-2)" "unprognostic (3.24e-2)" "unprognostic (8.58e-2)" "unprognostic (5.45e-2)" "prognostic favorable (1.01e-4)" "unprognostic (4.99e-3)" "unprognostic (1.37e-1)" "unprognostic (3.22e-1)" 0.0 0.0 0.6 0.0 0.4 0.4 0.0 0.7 0.5 0.0 51.2 6.9 0.9 0.0 0.0 0.0 0.0 0.0 0.2 3.5 1.5 74.4 0.1 0.0 0.0 1.7 1.5 0.0 9.1 0.5 0.2 0.0 1.4 0.0 7.7 0.2 2.4 0.0 0.0 0.0 0.3 0.2 0.2 0.0 0.2 2.8 2.2 0.2 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 44.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.7 0.5 3.5 1.5 1.7 1.5 1.4 0.2 2.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 27.6 0.0 0.0 0.0 21.1 33.2 0.1 5.5 0.7 0.1 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.0 0.0 0.0 0.0 15.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 8.9 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 4.8 0.0 TMEM74 "FLJ30668, NET36" ENSG00000164841 "Transmembrane protein 74" Q96NL1 8 108606850-108787594 "Predicted membrane proteins, Transporters" Autophagy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.2" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 4.6;Bipolar cells: 4.7;Cone photoreceptor cells: 6.2;Excitatory neurons: 5.1;Muller glia cells: 3.3;Rod photoreceptor cells: 8.3;Spermatogonia: 4.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 1.7;JURKAT: 1.5;NTERA-2: 2.1;RH-30: 1.5;SCLC-21H: 5.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015672, HPA076461" Uncertain Approved "Golgi apparatus,Cytosol" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 46: Photoreceptor cells - Phototransduction" "Golgi apparatus, Cytosol" "HPA015672: AB_1858132, HPA076461: " "unprognostic (8.99e-2)" "unprognostic (1.18e-1)" "unprognostic (4.25e-2)" "unprognostic (6.33e-2)" "unprognostic (2.05e-1)" "unprognostic (4.18e-1)" "unprognostic (1.95e-2)" "unprognostic (1.00e-1)" "unprognostic (2.54e-1)" "unprognostic (1.44e-2)" "unprognostic (2.01e-2)" "unprognostic (3.97e-2)" "unprognostic (3.75e-4)" "unprognostic (8.77e-2)" "unprognostic (6.36e-2)" "unprognostic (5.95e-2)" "unprognostic (1.46e-3)" 0.3 0.2 1.8 0.1 2.2 0.0 0.2 4.7 2.4 0.2 1.4 1.3 0.0 0.1 0.0 0.5 0.1 0.1 1.3 3.7 3.0 0.1 0.8 0.1 0.0 3.8 1.7 0.1 0.5 0.0 0.4 0.0 3.5 0.1 0.1 2.5 0.2 0.1 0.8 0.3 0.2 0.4 6.1 0.1 0.3 0.3 1.6 0.3 0.1 0.2 0.1 0.2 0.4 8.2 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.1 1.7 0.7 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.9 0.0 1.5 0.0 0.0 0.0 5.3 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.5 0.7 0.0 0.1 0.2 0.0 0.0 0.7 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 2.2 4.7 2.4 3.7 3.0 3.8 1.7 3.5 6.1 1.6 8.2 0.4 0.0 0.0 2.0 0.0 0.9 0.7 0.0 4.6 4.7 0.2 0.6 0.8 0.0 0.0 0.0 6.2 0.2 0.0 0.0 0.0 0.2 0.1 0.1 0.1 0.3 1.8 0.0 5.1 0.2 0.8 0.7 0.0 0.1 0.0 0.5 0.0 0.7 0.1 0.0 2.0 0.0 0.0 0.0 0.7 0.0 0.0 0.9 0.0 0.0 0.0 3.3 0.0 0.0 0.7 0.2 0.0 0.0 0.1 0.2 0.0 0.0 0.0 8.3 0.0 0.8 0.9 0.2 4.1 2.0 0.6 0.1 0.1 0.1 0.0 0.0 TMEM89 ENSG00000183396 "Transmembrane protein 89" A2RUT3 3 48620759-48621769 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "testis: 24.8" "Group enriched" "Detected in some" 16 "Early spermatids: 329.4;Late spermatids: 228.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA053577 Uncertain NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA053577: AB_2682196" "unprognostic (1.61e-1)" "unprognostic (2.50e-2)" "unprognostic (1.07e-1)" "unprognostic (1.75e-2)" "unprognostic (1.07e-1)" "unprognostic (1.94e-3)" "unprognostic (3.83e-1)" "unprognostic (1.42e-1)" "unprognostic (7.12e-2)" "unprognostic (2.02e-2)" "unprognostic (6.31e-3)" "unprognostic (5.90e-3)" "unprognostic (3.35e-2)" "unprognostic (3.83e-2)" "unprognostic (8.41e-2)" "unprognostic (2.71e-1)" "unprognostic (3.86e-2)" 0.1 0.0 0.1 0.0 0.1 1.7 0.1 0.1 0.4 0.1 0.0 0.6 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.1 0.2 0.0 0.1 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.1 0.3 0.6 0.1 0.0 0.1 0.5 24.8 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.3 0.1 0.3 0.2 0.0 0.0 0.0 0.1 0.5 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.3 0.2 0.1 0.0 0.3 0.0 0.4 0.6 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.5 0.1 0.1 0.0 0.1 0.1 0.0 0.2 0.4 0.0 0.2 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.3 0.4 0.9 0.4 0.1 0.2 0.1 0.5 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.4 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 329.4 0.0 0.0 0.1 1.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 228.6 2.8 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 1.4 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 17.3 1.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 TMEM97 MAC30 ENSG00000109084 "Transmembrane protein 97" Q5BJF2 17 28319200-28328685 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 113.4;pancreas: 322.0" "Cell type enhanced" "Detected in many" "Cholangiocytes: 121.5;Exocrine glandular cells: 196.4;Granulosa cells: 212.9;Hepatocytes: 226.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "CACO-2: 341.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044795, HPA076689" Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 39: CACO-2 - Unknown function" "Cluster 40: Granulosa cells - Unknown function" "Endoplasmic reticulum" "HPA044795: AB_10959306, HPA076689: " "unprognostic (1.35e-2)" "unprognostic (2.70e-1)" "unprognostic (1.39e-1)" "unprognostic (1.10e-3)" "unprognostic (1.81e-1)" "unprognostic (4.34e-2)" "unprognostic (3.20e-2)" "unprognostic (9.03e-2)" "unprognostic (1.04e-2)" "unprognostic (1.81e-1)" "unprognostic (1.11e-2)" "unprognostic (5.17e-2)" "prognostic unfavorable (1.24e-4)" "unprognostic (1.08e-1)" "unprognostic (2.26e-1)" "unprognostic (1.99e-1)" "unprognostic (4.01e-2)" 4.3 26.0 5.2 7.3 6.3 6.7 11.7 6.6 9.0 5.7 6.5 14.3 16.4 6.7 4.7 7.4 13.1 10.2 3.4 6.3 5.4 7.1 113.4 17.4 7.1 14.9 14.2 18.1 322.0 6.5 1.6 6.8 14.9 10.8 12.6 6.3 3.7 3.3 15.5 9.8 11.2 5.7 5.0 4.6 38.8 58.0 7.4 7.6 4.2 9.1 8.2 26.6 5.2 6.8 46.1 120.4 214.8 105.5 28.0 40.2 70.5 44.1 27.9 67.9 90.3 341.0 34.3 126.3 46.4 17.0 140.1 48.7 137.1 75.0 52.7 60.3 102.1 47.8 56.9 143.0 25.7 76.9 36.4 84.0 10.0 66.4 27.5 8.3 21.1 80.1 101.3 92.1 22.7 81.8 120.0 72.4 95.6 187.7 30.6 94.8 236.5 112.8 85.6 210.6 154.1 67.0 70.0 55.1 36.3 118.2 97.0 35.8 13.8 72.8 56.8 62.9 81.7 74.3 159.0 115.9 14.6 54.7 44.3 0.7 2.2 2.2 7.8 2.7 9.2 11.1 6.4 9.4 16.1 5.5 10.4 9.8 1.0 9.5 1.0 9.3 6.6 5.2 5.2 6.3 6.6 9.0 6.3 5.4 14.9 14.2 14.9 5.0 7.4 6.8 4.2 9.6 61.5 3.3 7.7 14.5 6.0 32.8 18.8 11.3 22.5 21.5 9.0 121.5 19.1 14.7 16.7 34.2 5.0 6.1 15.6 23.3 22.3 7.5 14.3 7.1 38.8 40.3 2.9 196.4 84.0 14.4 49.5 11.4 1.3 212.9 6.4 226.9 22.0 3.3 4.5 16.2 26.4 6.7 34.7 49.1 13.4 9.9 16.0 0.0 11.4 8.2 4.1 4.0 1.0 47.7 3.5 11.3 15.3 13.9 4.0 6.3 12.2 9.1 6.6 10.4 12.4 91.3 65.5 22.7 11.2 10.7 6.4 65.1 29.4 7.9 TMPRSS4 "MT-SP2, TMPRSS3" ENSG00000137648 "Transmembrane serine protease 4" Q9NRS4 11 118077012-118121890 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 108.7;intestine: 43.5;urinary bladder: 74.6" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 101.7;Club cells: 103.5;Distal enterocytes: 187.9;Squamous epithelial cells: 119.2;Urothelial cells: 258.6" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 5 "cerebellum: 1.8" "Immune cell enriched" "Detected in single" 7 "basophil: 2.1" "Lineage enriched" "Detected in single" 10 "granulocytes: 2.1" "Group enriched" "Detected in some" 5 "CAPAN-2: 103.7;HaCaT: 39.2;OE19: 141.6;RPTEC TERT1: 70.6;RT4: 95.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA006238 Uncertain "Secreted in other tissues" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA006238: AB_1080316" "unprognostic (1.48e-1)" "unprognostic (3.27e-2)" "unprognostic (1.19e-2)" "unprognostic (1.23e-1)" "unprognostic (5.23e-2)" "unprognostic (5.50e-2)" "unprognostic (8.17e-3)" "unprognostic (1.95e-2)" "unprognostic (2.41e-1)" "unprognostic (9.62e-2)" "prognostic unfavorable (3.14e-4)" "unprognostic (2.87e-3)" "unprognostic (2.80e-1)" "unprognostic (4.58e-2)" "unprognostic (1.06e-1)" "unprognostic (1.10e-2)" "unprognostic (9.96e-3)" 0.2 0.0 0.1 6.1 0.1 0.8 0.3 1.8 0.3 16.6 0.3 43.5 25.4 2.1 3.2 108.7 1.0 14.3 0.2 0.1 0.0 21.1 0.2 1.4 0.2 0.1 0.0 0.1 0.3 0.0 0.2 0.1 0.2 7.8 42.9 0.4 6.5 0.2 0.2 4.1 22.4 1.5 0.0 0.2 31.4 1.1 0.2 1.1 0.2 0.1 14.9 74.6 16.7 0.3 18.5 0.1 0.1 0.2 0.0 0.0 0.7 0.0 0.0 0.0 0.0 2.7 103.7 0.1 3.5 0.0 0.1 39.2 0.0 0.4 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 3.4 0.3 0.0 1.3 0.3 4.5 0.1 141.6 0.0 0.1 0.1 0.2 70.6 95.9 0.1 0.1 0.0 8.4 0.1 0.2 0.5 0.1 0.1 0.2 0.1 0.0 0.1 0.3 0.1 0.1 0.1 0.1 0.1 2.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.1 0.1 1.8 0.3 0.1 0.0 0.1 0.0 0.2 0.0 0.2 0.3 0.1 0.0 1.7 0.0 0.4 1.1 35.2 101.7 38.1 0.0 0.0 0.0 0.7 0.0 103.5 11.0 0.0 0.2 0.0 187.9 0.0 1.5 3.0 45.3 4.6 0.8 4.2 0.0 0.2 7.3 3.0 0.5 53.5 66.4 5.7 0.0 0.0 0.1 0.2 0.0 0.2 55.3 34.6 0.3 0.3 2.5 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 52.6 67.5 0.0 2.7 17.5 55.2 2.4 69.4 0.0 0.0 0.0 4.7 0.0 0.1 119.2 6.3 0.3 0.5 0.0 71.2 258.6 TMPRSS6 "FLJ30744, MT2" ENSG00000187045 "Transmembrane serine protease 6" Q8IU80 22 37065436-37109713 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "liver: 128.4" "Group enriched" "Detected in some" 11 "Early spermatids: 61.0;Hepatocytes: 99.9;Late spermatids: 143.9" "Group enriched" "Detected in many" 14 "liver cancer: 51.3;thyroid cancer: 14.1" "Group enriched" "Detected in some" 4 "basal ganglia: 4.4;thalamus: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Hep G2: 5.0;SCLC-21H: 8.1" "Not detected" "Not detected" "Region enhanced" "Detected in single" "basal ganglia: 3.3" NA NA "Cluster 62: Liver - Hemostasis" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (3.93e-1)" "unprognostic (3.28e-1)" "unprognostic (8.62e-2)" "unprognostic (6.29e-5)" "unprognostic (7.95e-2)" "unprognostic (1.62e-1)" "prognostic favorable (8.16e-6)" "unprognostic (2.44e-1)" "unprognostic (3.07e-1)" "unprognostic (2.41e-1)" "unprognostic (1.16e-2)" "unprognostic (3.58e-2)" "unprognostic (1.15e-7)" "unprognostic (2.38e-1)" "unprognostic (9.15e-2)" "unprognostic (2.39e-2)" "unprognostic (3.86e-5)" 0.1 0.1 0.2 0.2 4.4 0.2 0.4 0.1 0.6 0.1 0.0 0.6 2.2 0.1 0.8 0.2 0.5 0.9 0.0 0.2 0.2 0.1 128.4 0.7 0.3 0.2 0.4 0.1 1.3 0.0 13.0 0.7 0.2 0.2 0.5 0.1 0.0 0.0 0.0 2.2 1.0 0.0 0.0 0.2 3.6 7.7 1.3 0.4 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.6 0.1 0.3 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.5 0.2 0.1 5.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.3 0.0 0.9 0.0 0.0 0.2 0.1 0.1 0.3 0.1 0.2 0.0 0.0 8.1 0.3 0.1 0.6 0.0 0.1 0.1 0.0 0.4 0.3 1.0 0.1 0.0 1.0 0.3 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 4.4 0.1 0.6 0.2 0.2 0.2 0.4 0.2 0.0 1.3 0.1 0.0 0.0 0.0 0.3 0.6 0.5 0.0 0.0 0.0 0.0 0.6 0.3 0.5 2.8 0.0 0.0 0.0 0.0 0.1 8.8 0.0 0.2 61.0 0.0 0.0 0.3 5.3 8.0 0.1 0.0 2.6 0.0 2.6 0.0 0.0 0.0 2.5 99.9 0.1 0.0 0.1 1.5 0.0 3.2 0.0 143.9 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.6 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.8 0.0 0.1 0.3 0.3 0.1 0.6 0.0 TMSB15A "TMSL8, TMSNB" ENSG00000158164 "Thymosin beta 15A" P0CG34 X 102513682-102516739 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 13.0;prostate: 15.8" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 12.8;Granulosa cells: 25.9;Prostatic glandular cells: 13.8;Smooth muscle cells: 13.5;Spermatogonia: 19.8" "Group enriched" "Detected in many" 4 "glioma: 20.1;prostate cancer: 56.4;testis cancer: 14.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 571.5;HAP1: 110.2;MOLT-4: 113.4;NTERA-2: 148.0;RH-30: 259.9;SH-SY5Y: 148.1" "Low region specificity" "Detected in all" NA NA 130000 "Cluster 48: NK-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" "unprognostic (5.33e-3)" "unprognostic (3.09e-2)" "unprognostic (1.70e-2)" "unprognostic (5.82e-3)" "unprognostic (1.34e-1)" "unprognostic (4.03e-2)" "unprognostic (5.65e-2)" "unprognostic (1.34e-1)" "unprognostic (6.88e-2)" "unprognostic (1.59e-2)" "unprognostic (1.45e-1)" "unprognostic (2.53e-1)" "unprognostic (3.18e-3)" "unprognostic (2.96e-4)" "unprognostic (2.14e-1)" "unprognostic (7.83e-2)" "unprognostic (2.07e-1)" 1.0 1.0 1.1 1.1 1.2 1.0 5.1 1.7 2.1 5.1 1.4 0.9 0.4 5.0 0.7 0.3 1.9 1.2 1.9 1.2 1.1 2.4 0.1 7.1 4.0 1.3 1.0 4.7 0.9 0.8 0.8 0.5 1.3 15.8 1.1 1.4 3.9 1.2 0.3 0.5 0.6 2.3 1.1 0.4 0.5 4.8 1.2 13.0 5.9 0.3 2.8 0.7 2.3 1.1 0.1 0.0 571.5 107.7 2.4 0.3 0.2 12.4 0.7 1.7 4.8 0.0 0.7 0.0 1.3 2.1 28.5 0.0 110.2 0.7 1.2 0.0 5.6 10.3 1.7 0.3 0.3 0.2 10.1 1.4 0.0 1.1 0.0 14.3 6.7 5.5 1.0 0.0 41.2 0.1 113.4 0.2 148.0 0.0 1.4 0.2 259.9 0.0 11.7 0.2 98.1 148.1 14.0 0.9 0.3 22.0 1.4 3.2 2.4 0.3 62.6 1.4 10.5 11.8 2.1 0.0 6.7 0.0 25.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.1 1.1 1.2 1.7 2.1 1.2 1.1 1.3 1.0 1.3 1.1 1.2 1.1 1.4 0.0 0.0 0.0 0.0 0.8 0.9 0.1 1.8 0.3 7.3 12.8 0.1 0.0 0.0 0.0 0.0 0.5 0.5 0.5 0.0 0.5 0.3 0.5 5.6 1.2 0.0 0.8 0.0 0.0 0.5 4.6 0.0 1.2 0.0 25.9 2.5 0.0 0.5 0.0 0.0 0.6 0.0 0.6 0.5 0.1 0.3 0.1 1.8 0.0 0.0 0.7 1.0 0.5 0.0 0.0 0.1 2.6 0.3 13.8 0.1 0.4 0.0 0.1 6.6 1.2 13.5 3.4 19.8 1.8 0.0 0.3 0.7 0.9 0.9 1.0 TMTC1 "ARG99, FLJ31400, FLJ41625, OLF" ENSG00000133687 "Transmembrane O-mannosyltransferase targeting cadherins 1" Q8IUR5 12 29500840-29784759 "Enzymes, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 105.0;Astrocytes: 64.6;Excitatory neurons: 186.0;Inhibitory neurons: 200.5;Skeletal myocytes: 60.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HHSteC: 83.0;HSkMC: 56.9;hTERT-HME1: 103.8;LHCN-M2: 58.8;RH-30: 122.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016720 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 39: Non-specific - Mitochondria" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Cytosol" "HPA016720: AB_1858155" "unprognostic (1.67e-1)" "unprognostic (6.35e-3)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.90e-4)" "unprognostic (1.63e-3)" "unprognostic (4.53e-2)" "unprognostic (3.88e-2)" "unprognostic (8.36e-2)" "unprognostic (1.77e-1)" "unprognostic (8.90e-3)" "unprognostic (3.08e-3)" "unprognostic (1.21e-1)" "prognostic unfavorable (5.49e-4)" "unprognostic (5.89e-3)" "unprognostic (6.38e-2)" "unprognostic (2.90e-1)" "unprognostic (4.51e-3)" 36.7 14.1 14.5 5.2 21.0 0.2 16.8 6.7 13.5 11.9 13.3 11.9 3.1 9.0 3.0 6.8 14.3 7.1 16.5 20.0 25.0 14.7 2.4 8.7 2.7 11.4 24.0 9.3 2.6 28.0 10.7 2.8 15.8 6.9 5.9 2.6 4.5 8.8 18.5 4.0 6.4 13.2 7.9 42.4 8.3 2.4 25.1 6.9 4.7 31.2 2.1 12.1 8.2 6.3 0.0 0.0 15.3 0.0 47.7 31.6 0.1 14.7 33.1 4.3 3.4 0.0 0.2 0.1 7.4 10.0 17.6 0.0 0.5 0.2 0.2 0.3 4.6 0.0 41.5 0.7 83.0 2.1 0.0 56.9 5.6 40.3 103.8 12.2 2.2 0.0 0.0 2.2 58.8 0.0 0.0 0.0 11.1 0.2 20.8 0.0 122.4 2.1 0.0 0.3 1.2 1.2 1.7 0.0 4.1 5.4 0.0 0.8 6.2 3.7 2.4 2.3 12.5 19.6 0.0 0.0 27.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 14.5 21.0 6.7 13.5 20.0 25.0 11.4 24.0 15.8 7.9 25.1 6.3 105.0 3.2 0.6 64.6 0.9 3.3 1.0 6.1 11.4 12.1 1.3 10.4 32.3 0.0 2.4 3.7 0.0 0.1 0.0 0.0 0.0 0.1 29.6 7.7 16.2 57.9 0.0 0.0 186.0 0.0 0.0 17.5 2.0 7.0 0.0 4.3 54.7 5.4 0.5 0.0 200.5 0.2 0.0 17.7 4.2 7.5 8.1 4.9 10.6 30.9 0.5 0.5 0.0 9.5 5.7 0.0 0.0 18.4 0.3 4.0 0.1 0.7 6.0 1.3 46.0 60.3 24.9 2.4 1.7 1.3 2.0 1.9 1.0 21.9 0.0 0.4 TNC "DFNA56, HXB, MGC167029, TN" ENSG00000041982 "Tenascin C" P24821 9 115019575-115118257 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Cancer-related genes, Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 376.2" "Cell type enhanced" "Detected in many" "Astrocytes: 160.3;Basal prostatic cells: 72.1;Basal respiratory cells: 150.6;Basal squamous epithelial cells: 126.3;Prostatic glandular cells: 69.2;Smooth muscle cells: 58.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 798.5;hTEC/SVTERT24-B: 634.4;U-138 MG: 526.0;U-251 MG: 484.5;U-87 MG: 711.8;WM-115: 1253.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004592, HPA004823" Approved "Secreted to extracellular matrix" NA NA 560000000 840000000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 17: WM-115 - Nervous system development" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "CAB004592: AB_628342, HPA004823: AB_1080243" "unprognostic (5.46e-2)" "unprognostic (3.76e-2)" "unprognostic (7.57e-2)" "unprognostic (1.69e-1)" "unprognostic (9.20e-2)" "unprognostic (1.39e-1)" "unprognostic (2.07e-1)" "unprognostic (9.68e-2)" "unprognostic (7.86e-3)" "unprognostic (2.68e-3)" "unprognostic (1.59e-2)" "unprognostic (1.82e-1)" "unprognostic (4.87e-3)" "unprognostic (1.79e-2)" "unprognostic (1.92e-2)" "unprognostic (7.60e-2)" "unprognostic (1.97e-3)" 61.0 4.7 16.4 170.4 28.5 0.9 41.2 14.0 9.8 43.6 3.0 174.3 16.7 106.8 12.2 23.9 25.5 14.1 32.6 15.6 34.3 82.0 7.7 54.2 39.8 20.3 43.8 5.3 4.8 2.3 7.2 4.0 28.0 39.1 28.3 4.8 19.8 33.3 6.2 25.9 56.5 376.2 15.0 40.8 62.4 4.8 65.4 17.1 13.3 3.2 22.6 96.7 15.9 20.5 25.1 6.0 6.9 1.3 37.5 10.1 0.1 205.7 798.5 425.4 203.6 5.3 55.3 0.0 32.8 291.7 6.9 89.9 0.0 12.0 241.3 0.4 2.2 0.0 4.8 0.0 0.7 0.4 3.9 6.2 1.7 634.4 289.9 42.9 0.1 0.0 0.0 5.2 11.4 0.0 0.1 0.3 65.2 0.9 85.3 0.2 451.9 0.1 373.3 0.1 0.6 5.9 91.4 0.2 19.3 140.9 1.0 1.4 0.1 526.0 88.4 94.2 484.5 14.3 0.4 0.4 711.8 0.6 1253.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 16.4 28.5 14.0 9.8 15.6 34.3 20.3 43.8 28.0 15.0 65.4 20.5 0.7 12.8 43.5 160.3 0.4 12.1 72.1 150.6 126.3 0.1 9.3 33.3 1.4 0.0 14.8 1.8 0.0 1.1 0.3 0.0 0.0 25.8 15.4 6.7 47.8 11.1 0.0 0.0 7.0 4.5 0.6 19.0 0.0 24.9 2.5 0.5 6.1 0.0 1.2 0.0 0.9 0.0 0.0 0.6 4.7 18.4 3.4 0.9 5.4 1.9 0.1 1.3 0.0 4.0 0.8 3.9 0.0 0.4 0.3 69.2 0.0 0.3 3.5 0.2 0.0 1.3 58.9 0.4 0.2 4.8 4.5 1.0 2.6 0.1 0.1 5.8 TNFAIP1 "B12, B61, BTBD34, EDP1, MGC2317" ENSG00000109079 "TNF alpha induced protein 1" Q13829 17 28335602-28347009 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Pancreatic endocrine cells: 112.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "CACO-2: 166.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013333, HPA014641" Uncertain Approved Nucleoli NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 39: CACO-2 - Unknown function" "Cluster 1: Pancreatic cells - Digestion" Nucleoli "HPA013333: AB_1858160, HPA014641: AB_1858159" "unprognostic (4.42e-1)" "unprognostic (1.54e-2)" "unprognostic (4.32e-2)" "prognostic unfavorable (7.48e-5)" "unprognostic (2.29e-1)" "unprognostic (4.97e-3)" "unprognostic (3.21e-1)" "unprognostic (1.94e-1)" "unprognostic (2.64e-2)" "unprognostic (1.31e-2)" "unprognostic (8.27e-3)" "unprognostic (1.43e-2)" "unprognostic (4.21e-3)" "unprognostic (2.49e-2)" "unprognostic (2.04e-1)" "unprognostic (4.09e-1)" "unprognostic (7.02e-2)" 36.1 30.4 32.4 19.3 31.1 8.1 30.3 28.5 32.0 22.0 38.6 19.9 17.7 21.7 14.9 39.6 19.2 28.9 46.7 30.9 29.1 35.9 54.8 40.9 17.0 30.3 30.1 17.4 37.6 23.0 17.5 44.7 29.4 20.5 16.9 26.3 23.9 20.5 23.3 29.0 17.7 30.9 28.9 50.2 25.4 17.2 35.7 22.0 24.0 23.8 19.5 35.1 23.4 28.9 43.3 61.3 40.2 28.4 34.3 30.1 39.0 50.4 62.4 60.6 47.6 166.1 25.8 8.7 34.4 67.0 29.4 49.1 22.3 86.9 46.5 24.0 28.0 7.7 66.0 24.2 45.9 13.5 12.5 38.9 99.7 47.7 37.0 56.9 71.7 17.4 20.0 12.8 28.8 25.8 25.6 7.4 9.3 36.4 22.3 11.3 50.8 15.5 89.5 45.9 29.3 31.7 62.3 102.5 25.8 55.8 42.9 11.4 76.4 44.2 43.7 34.4 39.3 20.8 18.7 9.3 34.3 9.0 28.5 1.7 7.2 9.5 6.5 7.0 7.7 5.3 4.7 5.9 9.3 3.9 4.5 5.5 2.5 9.1 8.7 4.5 4.3 5.0 32.4 31.1 28.5 32.0 30.9 29.1 30.3 30.1 29.4 28.9 35.7 28.9 66.6 38.5 12.9 5.5 4.6 24.6 47.5 32.0 12.5 25.6 18.2 11.9 21.8 20.0 17.5 22.0 16.7 31.5 6.2 14.3 23.5 60.5 40.1 23.0 13.9 62.4 17.4 7.4 11.7 82.5 34.9 13.5 12.8 30.2 7.0 14.0 60.3 29.5 11.0 11.8 7.5 11.0 10.2 12.5 12.1 6.9 7.8 7.0 0.0 9.4 30.1 10.0 4.1 7.1 7.2 112.9 15.1 7.9 7.1 46.9 13.6 16.9 20.2 9.8 13.1 10.9 22.3 5.4 5.6 15.9 28.4 69.2 5.0 18.1 9.7 43.0 TNFRSF10C "CD263, DcR1, LIT, TRAILR3, TRID" ENSG00000173535 "TNF receptor superfamily member 10c" O14798 8 23102921-23117445 "Cancer-related genes, CD markers, Predicted membrane proteins" Apoptosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 21.0;lymphoid tissue: 23.8" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 6.4;Alveolar cells type 2: 7.9;Endothelial cells: 5.3;Gastric mucus-secreting cells: 13.7;granulocytes: 8.8;Proximal enterocytes: 6.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 6 "neutrophil: 3195.8" "Lineage enriched" "Detected in many" 120 "granulocytes: 3195.8" "Group enriched" "Detected in many" 5 "BEWO: 108.8;HUVEC TERT2: 91.2" CAB025635 Enhanced NA NA 14600000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 28: BEWO - Transcription regulation" "Cluster 60: Granulocytes - Receptor signaling" "CAB025635: " "unprognostic (2.63e-1)" "unprognostic (4.49e-3)" "unprognostic (7.21e-3)" "unprognostic (2.07e-2)" "unprognostic (3.55e-2)" "unprognostic (1.46e-1)" "unprognostic (1.81e-2)" "unprognostic (2.11e-3)" "unprognostic (5.56e-2)" "unprognostic (4.37e-2)" "unprognostic (8.98e-2)" "unprognostic (1.94e-3)" "unprognostic (2.74e-3)" "unprognostic (4.83e-1)" "unprognostic (1.84e-1)" "unprognostic (1.34e-3)" "unprognostic (6.54e-2)" 8.3 1.8 1.2 23.8 1.0 21.0 1.0 0.9 2.4 4.1 1.7 2.8 2.0 1.1 0.7 2.2 4.7 12.7 1.6 0.7 1.0 2.6 2.6 7.5 1.6 1.6 1.2 0.5 2.5 1.8 1.1 8.3 1.6 1.8 3.0 0.1 1.1 1.5 0.5 0.4 2.4 3.1 1.4 18.4 2.6 0.8 1.6 2.9 3.6 7.2 1.3 6.9 0.4 1.3 0.7 3.6 1.3 3.4 0.0 0.7 108.8 4.4 0.0 0.3 0.4 0.0 4.1 0.2 1.4 3.9 0.3 0.6 0.2 0.4 0.2 4.4 1.1 0.4 1.1 1.2 11.2 0.5 2.0 12.1 0.8 2.0 0.8 1.6 91.2 0.2 0.0 0.0 0.8 3.2 0.0 2.6 4.2 0.2 0.1 0.2 0.1 0.0 19.4 0.4 0.0 0.2 0.2 0.2 1.0 9.7 14.7 0.6 18.0 1.0 2.3 3.3 0.3 3.4 1.3 0.0 4.9 0.9 1.7 57.8 26.7 511.0 0.1 14.4 0.3 1.4 0.5 0.1 6.0 0.4 0.6 0.3 3195.8 1.4 21.5 0.4 0.4 9.2 1.2 1.0 0.9 2.4 0.7 1.0 1.6 1.2 1.6 1.4 1.6 1.3 1.0 6.4 7.9 0.3 0.2 0.3 0.3 1.5 0.6 0.0 0.1 0.0 0.4 2.8 4.7 3.7 0.0 1.1 0.0 0.3 0.0 0.4 1.0 0.5 0.1 5.3 1.8 0.0 0.1 0.4 0.9 0.8 13.7 0.2 8.8 0.0 1.8 0.0 2.4 0.0 0.0 0.5 0.0 1.6 0.6 0.4 0.0 2.5 0.0 1.0 1.6 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 6.2 0.0 1.8 0.1 0.0 0.4 0.3 0.6 1.5 0.2 0.1 1.1 0.9 0.3 0.4 0.4 TNFRSF11A "CD265, FEO, LOH18CR1, PDB2, RANK" ENSG00000141655 "TNF receptor superfamily member 11a" Q9Y6Q6 18 62325287-62391288 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Deafness, Disease variant, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 30.5;salivary gland: 25.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 35.6;Intestinal goblet cells: 24.0;Paneth cells: 42.3;Proximal enterocytes: 25.5;Undifferentiated cells: 42.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 8 "NK-cell: 5.3" "Lineage enriched" "Detected in single" 8 "NK-cells: 5.3" "Cell line enriched" "Detected in many" 6 "HDLM-2: 125.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB010391, HPA047976" Approved Supported "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 110000 "Cluster 48: NK-cells - Unknown function" "Cluster 56: Intestine - Transmembrane transport" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" Cytosol "CAB010391: AB_2205352, HPA047976: AB_2680227" "unprognostic (4.08e-1)" "unprognostic (2.71e-1)" "unprognostic (3.23e-3)" "unprognostic (1.73e-1)" "unprognostic (6.03e-2)" "unprognostic (1.35e-1)" "unprognostic (9.96e-4)" "unprognostic (4.24e-3)" "unprognostic (7.79e-4)" "unprognostic (1.52e-1)" "unprognostic (4.05e-2)" "unprognostic (2.88e-1)" "unprognostic (4.69e-5)" "unprognostic (1.56e-1)" "unprognostic (1.78e-1)" "unprognostic (4.02e-2)" "unprognostic (7.07e-2)" 1.8 1.1 0.8 5.7 1.6 0.4 4.1 0.1 1.9 1.4 0.3 17.1 30.5 0.9 0.3 2.8 0.9 7.6 0.6 2.0 1.1 0.4 0.6 1.0 1.2 0.7 1.1 0.4 1.7 0.9 6.8 3.2 0.2 1.3 17.6 0.2 25.4 2.7 0.3 2.7 18.6 1.7 0.7 0.8 5.5 0.9 1.2 1.0 1.2 0.1 1.9 1.6 1.6 2.1 3.2 2.2 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.1 1.6 0.4 0.6 0.0 3.5 0.4 1.4 2.2 8.3 0.9 0.2 125.9 5.4 0.0 1.3 1.7 0.0 0.5 1.3 0.2 0.4 0.8 3.1 4.2 3.1 0.3 0.0 0.0 0.0 1.1 0.0 0.1 5.9 7.0 19.3 0.4 0.0 0.6 1.5 1.5 20.4 0.7 0.6 3.0 0.1 0.8 1.3 0.4 2.0 0.0 0.1 0.1 0.0 1.2 0.0 0.1 0.3 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 5.3 0.0 0.3 0.6 0.0 0.8 1.6 0.1 1.9 2.0 1.1 0.7 1.1 0.2 0.7 1.2 2.1 0.4 0.0 2.2 0.0 0.4 1.3 3.8 1.1 0.6 0.6 4.5 3.3 1.3 8.6 2.3 0.0 0.0 0.1 3.3 35.6 0.0 8.3 0.3 3.2 0.5 5.3 10.8 0.0 4.0 7.5 0.6 0.7 11.7 6.2 0.0 2.0 7.1 0.3 15.5 3.3 0.2 24.0 0.0 17.0 2.4 0.4 0.6 7.7 1.8 8.4 19.7 0.0 3.1 0.5 0.4 14.7 42.3 0.0 0.5 2.8 25.5 0.0 3.8 0.2 0.0 0.5 0.4 0.8 1.9 1.7 2.3 0.1 0.7 0.0 42.2 4.4 TNFRSF1B "CD120b, p75, TNF-R-II, TNF-R75, TNFBR, TNFR2, TNFR80" ENSG00000028137 "TNF receptor superfamily member 1B" P20333 1 12166991-12209228 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" Apoptosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 68.4" "Cell type enhanced" "Detected in many" "dendritic cells: 268.7;Kupffer cells: 200.5;Langerhans cells: 288.0;Macrophages: 230.2;monocytes: 175.3;T-cells: 138.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 387.1" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 34.0;K-562: 45.7;THP-1: 51.8;U-87 MG: 30.8;U-937: 37.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA004796 Approved "Secreted to blood" NA NA 3230000 8100000 "Cluster 51: Monocytes - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" "HPA004796: AB_1078436" "unprognostic (4.45e-2)" "unprognostic (2.27e-3)" "unprognostic (7.62e-2)" "unprognostic (3.82e-3)" "unprognostic (6.30e-2)" "unprognostic (4.47e-3)" "unprognostic (5.28e-3)" "unprognostic (2.79e-1)" "unprognostic (1.69e-2)" "unprognostic (1.73e-2)" "unprognostic (7.26e-2)" "unprognostic (2.48e-1)" "prognostic unfavorable (8.35e-5)" "unprognostic (2.02e-1)" "prognostic unfavorable (8.68e-4)" "unprognostic (3.26e-2)" "unprognostic (1.10e-1)" 45.6 5.4 3.9 68.4 3.8 52.1 34.7 4.8 17.9 14.3 5.6 12.8 16.8 11.6 0.4 5.5 14.6 15.6 10.9 3.7 9.0 7.5 15.7 32.0 32.1 18.3 7.2 6.3 5.9 2.3 4.5 35.8 10.6 6.4 10.8 0.8 6.5 2.6 10.7 7.8 23.9 16.8 9.0 53.3 16.4 2.2 8.9 12.7 7.6 6.3 21.3 28.9 8.8 14.1 0.0 0.3 4.1 0.0 9.6 13.5 8.9 1.1 2.0 4.0 4.3 1.8 34.0 0.2 0.6 3.9 5.6 0.0 0.8 0.0 2.2 14.5 0.0 0.0 0.2 0.0 25.2 0.3 3.8 14.8 0.0 13.0 0.0 7.2 19.6 0.2 45.7 6.4 1.5 0.0 0.0 8.1 0.2 4.9 1.4 1.2 0.4 25.9 0.0 0.8 0.0 0.1 0.6 0.4 1.4 6.4 0.0 51.8 7.8 5.3 0.2 27.0 0.0 1.9 0.0 0.0 30.8 37.0 1.4 0.6 127.1 18.2 48.4 260.5 26.5 13.5 34.4 40.5 71.7 8.4 9.8 15.5 138.0 13.4 387.1 15.1 70.9 150.4 3.9 3.8 4.8 17.9 3.7 9.0 18.3 7.2 10.6 9.0 8.9 14.1 99.4 9.6 15.9 0.7 42.8 16.8 3.9 1.0 1.2 0.2 3.2 4.1 3.6 5.7 6.5 3.7 0.0 0.9 268.7 12.8 0.0 0.5 0.6 1.7 5.1 46.0 0.0 7.4 0.2 0.6 6.3 13.2 12.8 4.9 2.5 1.4 31.1 17.0 72.6 0.0 0.2 3.0 0.0 200.5 288.0 1.2 2.1 230.2 16.0 30.9 175.3 0.3 109.2 0.0 0.1 0.7 4.2 0.4 72.5 8.0 25.8 0.4 1.5 1.2 32.9 6.8 9.8 0.0 0.9 0.7 10.5 30.1 138.4 1.9 4.8 8.8 TNFSF4 "CD252, gp34, OX-40L, TXGP1" ENSG00000117586 "TNF superfamily member 4" P23510 1 173183731-173207331 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins" Cytokine "Cancer-related genes, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 8.5;Granulosa cells: 37.0;Macrophages: 26.4;monocytes: 8.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 42.0;HHSteC: 17.3;HUVEC TERT2: 81.2;LHCN-M2: 67.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA059579 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 51: Myeloid cells - Hemostasis" "Nucleoplasm, Vesicles" "HPA059579: AB_2684071" "unprognostic (1.88e-2)" "unprognostic (1.20e-1)" "unprognostic (4.58e-2)" "unprognostic (2.74e-1)" "unprognostic (1.73e-2)" "unprognostic (1.74e-1)" "unprognostic (1.13e-3)" "unprognostic (2.13e-1)" "unprognostic (8.65e-2)" "unprognostic (5.17e-2)" "unprognostic (1.26e-2)" "unprognostic (1.18e-1)" "unprognostic (1.11e-7)" "unprognostic (3.73e-3)" "unprognostic (2.66e-1)" "unprognostic (9.49e-2)" "unprognostic (2.98e-2)" 1.2 2.0 1.1 2.3 1.2 0.6 0.6 1.8 1.5 1.0 0.1 1.0 0.3 0.8 0.5 0.6 0.9 1.1 1.0 1.1 0.9 0.8 0.9 1.2 2.2 1.2 1.2 1.1 1.1 0.5 1.5 0.5 1.2 1.4 1.2 1.4 0.4 0.6 0.2 0.3 0.8 0.8 0.8 1.7 0.7 4.0 1.1 3.7 0.4 0.2 1.9 1.5 0.8 1.2 0.1 0.0 0.4 1.2 2.7 14.1 0.2 4.1 0.9 0.2 0.3 0.2 0.1 0.2 0.7 42.0 0.2 0.1 0.1 0.1 0.3 0.7 0.1 0.1 0.4 1.6 17.3 0.3 0.2 6.2 0.3 2.1 0.3 1.3 81.2 1.5 0.1 0.5 67.5 0.0 0.7 0.4 0.3 0.1 0.6 2.0 0.1 0.6 0.6 0.1 0.1 0.6 0.3 0.2 0.9 1.3 0.0 0.7 0.6 0.1 0.1 0.4 0.2 0.9 1.4 0.3 0.2 7.7 4.4 0.0 0.1 0.1 0.5 0.0 0.3 0.5 0.2 0.4 0.3 0.5 0.4 0.4 0.7 1.7 0.0 1.2 0.4 2.8 1.1 1.2 1.8 1.5 1.1 0.9 1.2 1.2 1.2 0.8 1.1 1.2 0.2 0.0 0.5 8.5 0.8 0.8 0.3 0.4 0.6 0.4 0.2 0.0 1.5 1.5 0.1 1.8 0.0 0.2 2.2 0.9 0.0 0.1 5.8 0.2 0.4 1.0 0.0 0.8 3.6 0.0 0.2 3.7 0.0 0.1 0.0 37.0 0.0 1.2 0.5 0.0 5.2 0.0 0.0 0.6 2.3 2.2 0.3 26.4 1.8 0.0 8.2 1.3 2.1 2.5 4.0 0.3 0.1 1.9 0.4 0.4 0.0 0.2 0.8 0.5 0.0 0.6 3.7 0.3 0.2 0.0 0.6 0.0 2.4 0.7 0.1 0.1 TNIP2 "ABIN-2, FLIP1, KLIP, MGC4289" ENSG00000168884 "TNFAIP3 interacting protein 2" Q8NFZ5 4 2741648-2756342 "Predicted intracellular proteins" "Apoptosis, Inflammatory response, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 174.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020818, HPA049886, HPA063197" Supported Enhanced Nucleoplasm,Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 72: Non-specific - Transcription" "Cluster 15: RT4 - Unknown function" "Cluster 45: Enterocytes - Digestion" Nucleoplasm Cytosol "CAB020818: , HPA049886: AB_2680934, HPA063197: AB_2684960" "unprognostic (1.22e-1)" "unprognostic (2.09e-1)" "unprognostic (2.44e-1)" "prognostic favorable (1.13e-4)" "unprognostic (3.64e-1)" "unprognostic (9.87e-2)" "unprognostic (4.36e-2)" "prognostic unfavorable (5.73e-4)" "unprognostic (2.77e-1)" "unprognostic (2.47e-2)" "unprognostic (8.34e-2)" "unprognostic (1.13e-1)" "prognostic unfavorable (2.94e-5)" "unprognostic (3.00e-1)" "unprognostic (7.23e-2)" "unprognostic (1.97e-3)" "unprognostic (4.02e-3)" 30.0 19.9 15.8 16.5 16.6 23.9 26.3 16.3 18.5 20.9 15.7 32.1 17.7 20.2 6.4 27.2 18.1 10.6 31.4 14.8 15.9 37.1 30.1 29.9 17.6 18.0 16.9 18.8 22.8 5.5 19.7 15.7 17.0 24.5 10.5 2.6 19.2 9.2 41.5 19.6 39.4 9.9 16.9 31.2 27.8 22.9 17.3 10.8 22.3 13.6 15.9 30.2 20.8 16.3 24.4 32.6 10.1 15.4 31.5 21.6 43.7 25.8 22.9 23.6 22.9 37.2 38.5 22.1 28.7 28.3 52.9 15.8 18.3 29.8 13.8 17.2 23.0 26.4 19.9 41.9 39.0 21.9 32.2 27.9 26.5 26.1 23.5 18.1 33.9 19.8 27.4 30.4 16.5 50.6 29.0 53.6 26.6 35.9 55.0 18.9 15.3 11.6 25.5 26.9 15.1 17.0 20.2 21.0 29.6 17.2 23.0 32.0 40.0 18.2 20.1 29.0 40.4 31.3 22.8 16.0 33.3 39.1 20.2 7.6 8.9 27.1 7.4 13.9 8.1 9.6 11.3 12.5 8.7 14.4 9.2 7.6 8.4 5.7 14.8 4.0 13.3 6.3 15.8 16.6 16.3 18.5 14.8 15.9 18.0 16.9 17.0 16.9 17.3 16.3 48.2 6.4 9.8 3.6 40.7 61.3 49.3 42.5 19.4 2.0 25.3 17.8 13.2 7.2 19.0 14.7 2.1 52.4 44.6 56.0 13.7 58.2 2.3 26.0 26.4 46.7 19.2 8.2 1.1 59.6 106.1 28.4 28.5 33.3 13.3 21.4 41.0 16.7 34.5 0.0 0.7 38.0 24.4 21.2 112.7 7.5 21.5 34.6 26.6 3.7 71.8 12.4 48.4 0.5 3.4 71.8 63.0 17.7 21.2 86.6 174.3 46.8 13.0 6.8 19.7 18.7 38.0 23.6 62.4 28.1 79.0 95.6 44.9 17.1 38.0 84.7 TNKS "ARTD5, PARP-5a, PARP5A, pART5, TIN1, TINF1, TNKS1" ENSG00000173273 Tankyrase O95271 8 9555912-9782346 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis, mRNA transport, Protein transport, Translocation, Transport, Wnt signaling pathway" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 149.9;Excitatory neurons: 203.2;Inhibitory neurons: 230.6;Oligodendrocyte precursor cells: 313.1;Oligodendrocytes: 285.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA025690 Approved Approved "Nucleoplasm,Nuclear membrane,Nuclear bodies" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 21: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Nuclear membrane, Nuclear bodies" "HPA025690: AB_10602249" "unprognostic (2.07e-1)" "unprognostic (1.72e-2)" "unprognostic (5.45e-3)" "unprognostic (8.22e-2)" "unprognostic (2.42e-1)" "unprognostic (1.27e-2)" "unprognostic (4.75e-2)" "unprognostic (1.13e-1)" "unprognostic (9.06e-2)" "unprognostic (8.01e-2)" "unprognostic (6.21e-2)" "unprognostic (9.10e-2)" "unprognostic (4.14e-2)" "unprognostic (1.12e-1)" "unprognostic (5.43e-1)" "unprognostic (7.76e-2)" "unprognostic (5.36e-2)" 7.3 9.3 14.2 6.5 20.5 12.2 9.9 18.5 15.8 12.1 6.9 7.5 6.0 10.5 17.5 5.9 8.2 6.2 7.0 13.4 16.8 6.1 7.5 6.6 8.5 21.5 18.5 13.1 7.5 12.5 12.6 7.9 22.2 7.8 6.8 21.0 7.1 7.7 18.4 11.4 7.8 7.1 14.7 6.5 7.2 20.3 18.3 10.5 9.7 11.8 8.6 7.9 6.9 32.2 8.8 11.5 28.8 17.4 17.8 23.7 10.7 13.4 15.1 10.7 12.0 6.9 6.9 18.9 5.4 13.2 14.3 9.2 16.5 12.5 15.4 4.9 8.6 13.3 10.7 15.6 16.0 6.9 7.9 16.9 14.8 11.1 21.6 17.3 14.6 14.5 12.7 19.6 19.9 5.8 17.5 10.4 18.9 9.7 6.7 13.9 17.8 5.5 12.8 17.8 29.1 21.4 10.5 9.9 19.3 17.3 6.6 10.2 19.7 17.4 10.6 11.9 10.0 6.7 11.8 13.3 18.7 9.5 17.1 2.4 1.1 0.9 2.0 1.1 1.0 1.9 1.6 1.9 1.4 3.2 1.8 2.2 3.5 1.5 1.4 1.8 0.8 0.7 14.2 20.5 18.5 15.8 13.4 16.8 21.5 18.5 22.2 14.7 18.3 32.2 19.7 16.0 11.7 130.9 23.1 11.5 12.8 11.4 12.0 34.1 15.8 13.6 17.0 15.7 12.0 9.2 14.6 11.2 14.9 9.2 1.9 12.4 149.9 19.9 30.6 15.5 13.8 14.5 203.2 8.5 10.9 20.3 19.9 20.9 10.1 33.7 18.9 18.0 7.1 42.1 230.6 10.8 16.2 9.4 8.5 76.3 16.8 10.3 12.4 92.8 8.4 15.1 5.2 313.1 285.7 13.4 12.8 18.0 20.7 12.8 17.2 6.9 28.1 37.0 0.0 28.7 16.6 37.7 15.4 12.9 15.5 12.3 18.1 39.5 12.2 12.8 TNP2 TP2 ENSG00000178279 "Transition protein 2" Q05952 16 11267748-11269533 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 326 "testis: 49.3" "Cell type enriched" "Detected in some" 4 "Late spermatids: 919.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 34: Spermatids - Unknown function" "unprognostic (1.30e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 49.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 219.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 919.5 2.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TNS2 "C1-TEN, KIAA1075, TENC1" ENSG00000111077 "Tensin 2" Q63HR2 12 53046969-53064379 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 109.3;Hepatic stellate cells: 93.1;Leydig cells: 141.7;Peritubular cells: 114.0;Sertoli cells: 151.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 114.2;ASC TERT1: 78.1;HHSteC: 59.9;HSkMC: 86.2;hTERT-RPE1: 61.9;TIME: 52.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034659 Approved NA Yes "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA034659: AB_10603349" "unprognostic (1.04e-1)" "unprognostic (2.58e-1)" "unprognostic (5.21e-3)" "unprognostic (1.86e-1)" "unprognostic (3.59e-2)" "unprognostic (7.26e-2)" "unprognostic (6.29e-2)" "unprognostic (5.42e-2)" "unprognostic (1.48e-2)" "unprognostic (8.97e-3)" "prognostic favorable (1.72e-4)" "prognostic favorable (9.32e-4)" "unprognostic (4.46e-2)" "unprognostic (1.09e-2)" "unprognostic (8.46e-2)" "unprognostic (1.47e-1)" "unprognostic (2.76e-2)" 156.3 66.9 59.3 14.8 66.2 0.3 121.6 46.4 57.8 121.2 33.3 79.0 14.4 98.8 14.0 28.3 121.0 32.5 99.6 43.7 49.2 67.3 66.5 83.4 15.8 58.0 63.5 104.1 34.6 17.0 43.3 33.1 54.0 66.3 11.5 6.0 35.7 41.1 69.0 42.1 56.7 28.5 50.8 79.5 58.2 15.9 58.3 7.2 80.6 58.8 6.4 82.6 81.1 57.9 2.0 21.2 2.7 2.2 114.2 78.1 0.7 11.8 27.1 6.2 3.2 1.4 5.7 0.1 25.3 32.1 2.6 1.5 0.1 7.8 2.4 0.5 0.8 0.4 25.5 11.3 59.9 0.3 0.5 86.2 0.3 7.9 4.7 61.9 36.3 0.4 0.6 0.3 24.9 5.1 0.2 0.4 1.9 1.4 5.8 0.7 6.6 0.3 8.2 0.4 1.2 2.7 4.4 2.4 8.8 1.6 26.1 0.7 52.1 12.9 14.8 4.7 2.0 0.6 0.3 0.1 20.4 0.3 21.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 59.3 66.2 46.4 57.8 43.7 49.2 58.0 63.5 54.0 50.8 58.3 57.9 109.3 3.2 25.7 33.3 0.5 0.0 6.8 0.0 5.2 21.1 15.1 13.0 7.9 10.0 2.5 5.5 0.0 0.5 0.9 0.4 3.9 5.8 2.8 4.4 41.1 69.6 1.2 2.7 3.1 4.4 0.4 40.5 2.0 14.5 0.0 7.7 93.1 37.5 2.4 30.3 7.8 3.9 0.0 4.4 0.0 7.2 141.7 2.9 0.0 31.9 0.1 29.6 0.0 46.3 35.6 2.4 9.0 114.0 1.8 4.5 2.1 2.6 1.5 11.3 151.2 51.3 64.7 4.2 4.4 1.3 0.0 0.8 1.4 2.6 1.8 2.1 TNS3 "FLJ13732, H_NH0549I23.2, TEM6, TENS1" ENSG00000136205 "Tensin 3" Q68CZ2 7 47275154-47582558 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 90.8;Oligodendrocyte precursor cells: 150.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 4.0;intermediate monocyte: 3.2;memory B-cell: 2.3;myeloid DC: 2.6;naive B-cell: 1.9;non-classical monocyte: 3.2;plasmacytoid DC: 3.7" "Group enriched" "Detected in many" 7 "B-cells: 2.3;dendritic cells: 3.7;monocytes: 4.0" "Cell line enhanced" "Detected in many" "A549: 266.7;LHCN-M2: 170.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055338, HPA056015" Approved Enhanced "Focal adhesion sites" NA NA 8100 "Cluster 14: Monocytes - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 68: Oligodendrocytes - Mixed function" "Focal adhesion sites" "HPA055338: AB_2682789, HPA056015: AB_2683010" "unprognostic (1.46e-1)" "unprognostic (2.97e-2)" "unprognostic (1.34e-1)" "unprognostic (7.02e-2)" "unprognostic (9.04e-2)" "unprognostic (1.63e-1)" "unprognostic (1.17e-1)" "unprognostic (2.05e-1)" "unprognostic (8.00e-2)" "unprognostic (3.77e-2)" "unprognostic (3.70e-1)" "unprognostic (6.60e-2)" "prognostic favorable (5.21e-4)" "unprognostic (3.13e-2)" "unprognostic (4.41e-2)" "unprognostic (3.20e-2)" "unprognostic (9.09e-3)" 30.4 35.3 57.3 23.8 59.0 6.3 20.9 57.3 51.6 26.2 59.2 19.3 18.7 24.6 6.5 6.4 21.9 21.3 23.8 55.2 64.7 59.7 51.6 40.7 36.7 81.4 63.3 38.3 57.0 30.8 10.5 56.7 73.2 16.3 16.9 9.1 48.5 16.0 22.0 14.4 23.9 16.6 63.2 42.0 30.3 9.4 73.9 8.3 29.8 15.0 19.4 16.2 16.6 63.6 26.5 266.7 15.9 27.7 35.6 28.8 50.6 23.6 133.8 22.7 34.7 60.5 34.7 13.4 40.9 86.4 84.8 49.4 25.9 38.6 20.6 0.2 1.6 37.4 37.3 32.3 36.8 0.1 0.4 28.7 16.3 13.0 20.7 147.3 18.1 0.0 0.1 80.6 170.0 16.4 0.1 0.8 15.4 38.1 31.5 12.1 38.7 44.5 77.5 53.0 1.5 32.3 46.5 9.3 26.9 79.6 35.2 27.6 72.6 35.0 27.1 0.4 36.5 51.7 72.4 30.6 8.7 26.0 129.6 0.2 4.0 0.0 0.0 3.2 0.1 2.3 0.0 0.0 2.6 1.9 0.0 0.0 0.5 0.0 3.2 3.7 0.0 1.4 57.3 59.0 57.3 51.6 55.2 64.7 81.4 63.3 73.2 63.2 73.9 63.6 8.5 67.3 15.8 90.8 10.9 4.8 6.5 26.3 14.2 1.6 8.5 10.3 23.9 35.8 18.8 31.3 0.0 27.7 7.1 41.3 1.9 15.5 11.8 19.8 11.0 12.4 15.0 6.3 2.4 18.4 59.2 14.9 18.3 23.2 0.0 11.4 31.4 40.3 77.4 0.0 6.4 14.0 10.2 41.3 8.4 18.5 6.2 28.9 16.0 76.8 23.1 35.2 1.0 150.8 3.7 23.8 9.9 15.4 5.3 10.5 33.6 14.1 11.1 1.4 26.3 45.5 21.8 2.2 3.0 1.5 3.3 30.0 3.5 20.1 17.0 3.2 TOE1 hCaf1z ENSG00000132773 "Target of EGR1, exonuclease" Q96GM8 1 45340052-45343973 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 36.6;Spermatocytes: 51.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053775, HPA069119" Supported Enhanced "Nucleoplasm,Nuclear bodies" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "Nuclear bodies" Nucleoplasm "HPA053775: AB_2682259, HPA069119: AB_2686090" "unprognostic (7.20e-2)" "unprognostic (1.20e-1)" "unprognostic (7.15e-3)" "unprognostic (1.90e-2)" "unprognostic (3.33e-1)" "prognostic favorable (9.05e-4)" "prognostic unfavorable (6.12e-9)" "unprognostic (4.67e-2)" "unprognostic (4.84e-2)" "unprognostic (2.37e-2)" "unprognostic (6.03e-2)" "unprognostic (2.24e-1)" "prognostic unfavorable (2.71e-4)" "prognostic favorable (9.98e-4)" "unprognostic (1.81e-1)" "unprognostic (1.41e-2)" "unprognostic (2.08e-1)" 4.8 5.1 4.9 5.9 4.9 8.0 5.5 4.8 6.1 3.7 4.8 6.8 6.7 6.7 8.4 3.7 5.4 3.5 3.7 4.7 5.4 4.7 5.5 5.1 7.9 5.1 5.0 6.2 4.8 7.5 3.2 6.8 5.1 5.0 8.2 4.1 5.3 5.0 3.0 3.9 5.0 6.5 5.0 5.8 5.6 11.8 5.4 9.0 7.1 2.4 8.3 5.5 3.3 5.1 15.8 9.1 16.5 15.7 7.6 5.9 23.9 15.6 12.9 26.6 24.7 16.7 9.6 29.9 12.1 16.2 23.4 15.9 21.0 22.5 21.3 19.6 17.3 36.0 21.9 15.6 7.3 23.7 17.2 8.8 4.8 28.4 17.8 9.4 19.5 22.5 28.4 19.6 18.9 14.6 34.8 18.4 31.1 20.6 14.2 24.9 24.5 13.6 11.5 28.7 13.9 13.4 14.5 36.3 27.5 25.7 9.8 33.2 14.6 12.6 23.3 19.1 29.7 15.0 19.4 19.9 14.8 26.5 14.7 20.0 5.8 6.2 7.3 6.9 8.4 5.9 6.3 7.3 6.0 8.4 6.4 7.0 0.6 4.1 6.1 5.2 8.6 5.1 4.9 4.9 4.8 6.1 4.7 5.4 5.1 5.0 5.1 5.0 5.4 5.1 6.5 6.4 4.8 2.3 12.4 1.8 6.3 8.8 4.6 10.7 4.5 5.0 1.8 7.2 8.1 7.3 12.5 36.6 9.2 9.2 7.9 5.4 13.9 2.1 6.2 9.0 3.0 14.1 2.5 6.2 13.8 6.6 4.6 3.4 11.4 10.5 8.6 5.0 9.3 8.4 2.7 7.3 8.2 3.5 2.6 9.4 6.8 6.2 3.6 1.9 12.3 13.1 9.2 2.0 2.1 3.4 10.7 6.4 7.0 6.5 8.8 7.9 4.7 18.3 13.1 8.0 7.1 51.7 18.9 3.8 1.4 22.7 9.0 10.2 6.9 4.6 TOGARAM2 "Crescerin-2, FAM179A, FLJ43249, LOC165186" ENSG00000189350 "TOG array regulator of axonemal microtubules 2" Q6ZUX3 2 28956611-29052230 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "brain: 34.9;choroid plexus: 25.2;fallopian tube: 20.1" "Group enriched" "Detected in some" 4 "dendritic cells: 20.1;Endometrial ciliated cells: 65.4;Respiratory ciliated cells: 30.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "HMC-1: 2.3;JURKAT: 1.2;NB-4: 1.3" "Low region specificity" "Detected in many" "HPA037561, HPA037562, HPA075216" Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Plasma membrane" "HPA037561: AB_10670384, HPA037562: AB_2675545, HPA075216: " "unprognostic (8.35e-5)" "unprognostic (2.85e-3)" "unprognostic (1.41e-1)" "unprognostic (7.01e-3)" "unprognostic (6.41e-2)" "unprognostic (1.23e-2)" "unprognostic (1.11e-1)" "unprognostic (2.53e-3)" "unprognostic (3.93e-1)" "unprognostic (6.83e-2)" "unprognostic (2.32e-3)" "unprognostic (5.92e-2)" "unprognostic (3.94e-11)" "unprognostic (3.75e-2)" "unprognostic (4.46e-1)" "unprognostic (2.01e-2)" "unprognostic (2.81e-3)" 0.1 1.2 4.5 0.6 11.5 1.9 0.2 10.6 2.3 0.5 25.2 0.3 0.5 0.6 0.1 0.4 20.1 0.3 2.8 4.5 7.6 0.1 0.2 2.8 0.8 19.2 34.9 0.5 0.3 0.0 1.1 0.3 17.3 0.2 0.2 0.2 0.2 0.1 1.2 0.3 0.4 0.5 12.5 2.0 1.0 1.3 10.6 0.2 0.1 3.0 0.7 0.2 0.1 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.2 0.7 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.0 0.2 0.1 0.7 0.0 0.6 0.1 0.2 0.6 2.3 0.1 0.0 0.0 0.0 0.2 0.1 1.2 0.0 0.3 0.3 0.0 0.3 1.3 1.0 0.4 0.1 0.0 0.3 0.6 0.3 0.0 0.8 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.6 0.4 0.0 0.0 0.0 0.0 1.6 0.0 0.7 0.0 0.1 1.1 0.0 0.0 0.0 0.5 0.0 0.6 0.0 0.0 0.6 0.5 4.5 11.5 10.6 2.3 4.5 7.6 19.2 34.9 17.3 12.5 10.6 5.3 0.3 0.0 3.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 5.6 0.0 0.0 0.0 20.1 0.0 0.0 0.0 0.0 65.4 1.1 0.0 0.0 0.0 0.0 0.0 0.1 1.6 0.0 1.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.9 0.0 0.0 0.2 30.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 3.6 0.5 0.0 0.0 TOM1L2 ENSG00000175662 "Target of myb1 like 2 membrane trafficking protein" Q6ZVM7 17 17843511-17972422 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 180.5;Cone photoreceptor cells: 158.4;Oligodendrocytes: 123.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HaCaT: 104.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022541, HPA023304" Enhanced Approved "Golgi apparatus,Intermediate filaments" NA NA 73000 "Cluster 6: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 9: Photoreceptor cells - Phototransduction" "Intermediate filaments" "Golgi apparatus" "HPA022541: AB_1858182, HPA023304: AB_1858183" "unprognostic (2.32e-1)" "unprognostic (7.54e-2)" "unprognostic (1.12e-1)" "unprognostic (2.57e-2)" "unprognostic (3.25e-2)" "prognostic favorable (1.24e-4)" "unprognostic (2.22e-1)" "unprognostic (1.08e-1)" "unprognostic (6.29e-2)" "prognostic unfavorable (2.58e-4)" "prognostic favorable (1.92e-4)" "unprognostic (3.19e-2)" "prognostic favorable (6.21e-9)" "unprognostic (7.11e-2)" "unprognostic (1.40e-1)" "unprognostic (4.18e-2)" "unprognostic (4.51e-2)" 20.7 30.5 64.0 9.5 62.7 6.1 20.3 52.7 70.0 31.9 21.3 44.2 14.0 33.2 11.0 64.4 26.6 13.0 141.0 66.0 56.4 31.3 13.9 23.2 7.7 91.5 80.3 32.9 19.7 40.3 42.2 9.0 95.3 37.3 13.8 50.2 21.3 28.7 67.1 59.7 20.9 23.3 49.7 16.6 34.9 39.4 74.6 8.8 48.5 55.4 12.9 31.4 35.1 72.7 27.1 29.0 8.2 6.2 19.1 19.3 14.2 43.3 20.1 22.9 19.3 28.2 17.6 5.0 52.9 40.8 13.3 104.3 6.8 24.1 14.0 7.2 12.7 8.0 28.0 6.0 12.2 2.0 5.2 22.9 16.6 20.5 15.2 19.6 23.3 7.3 3.0 6.9 30.3 27.1 3.6 4.6 1.5 34.4 19.5 4.7 20.7 12.0 32.4 48.1 8.7 8.4 19.5 25.2 15.3 55.9 13.4 3.6 31.8 21.9 6.5 46.0 16.8 6.1 5.1 2.3 26.4 2.7 55.2 10.0 3.3 4.8 2.8 1.0 2.0 1.6 2.6 2.4 1.6 2.2 4.3 3.2 12.8 1.4 3.3 1.9 1.3 1.7 64.0 62.7 52.7 70.0 66.0 56.4 91.5 80.3 95.3 49.7 74.6 72.7 10.1 32.1 17.0 180.5 9.5 10.8 14.6 13.9 7.4 74.5 20.9 14.1 73.7 15.7 16.6 11.0 158.4 8.5 10.2 43.3 5.9 12.2 30.8 14.1 9.4 12.4 20.4 4.8 63.2 8.7 17.4 12.7 13.3 15.7 2.5 28.1 16.4 13.4 9.2 95.9 74.2 19.2 18.3 8.5 7.6 64.2 26.4 6.4 12.4 35.6 11.8 28.1 10.3 66.9 123.2 16.1 41.0 25.6 8.4 39.1 22.4 11.1 22.9 78.3 19.7 18.0 13.0 16.7 12.1 37.2 17.2 32.2 10.0 30.8 15.4 64.5 TOMM22 TOM22 ENSG00000100216 "Translocase of outer mitochondrial membrane 22" Q9NS69 22 38681957-38685421 "Predicted membrane proteins" "Protein transport, Translocation, Transport" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003037 Supported Enhanced Mitochondria NA NA 230000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 32: U-937 - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA003037: AB_1080329" "unprognostic (5.54e-2)" "unprognostic (5.04e-3)" "unprognostic (2.74e-3)" "unprognostic (1.48e-2)" "unprognostic (1.32e-1)" "unprognostic (1.85e-2)" "prognostic unfavorable (2.90e-5)" "unprognostic (1.01e-1)" "unprognostic (4.28e-1)" "unprognostic (7.01e-2)" "unprognostic (1.64e-2)" "unprognostic (7.39e-2)" "unprognostic (5.44e-2)" "unprognostic (5.32e-2)" "unprognostic (1.99e-1)" "unprognostic (7.86e-2)" "unprognostic (1.64e-1)" 19.6 21.1 27.6 19.0 28.5 30.4 17.2 29.0 29.7 16.6 29.4 22.6 24.5 15.5 19.2 28.4 20.5 11.5 29.1 27.7 28.7 23.9 28.5 12.7 25.3 28.6 28.2 19.1 21.1 22.5 9.9 15.7 28.9 15.1 27.6 8.6 21.4 12.5 34.6 22.1 19.4 19.4 28.0 17.0 20.3 17.0 29.6 27.0 17.1 31.0 30.5 23.8 17.8 28.3 61.7 35.5 53.4 56.9 38.6 35.7 57.5 49.7 34.3 71.1 53.1 65.0 35.8 62.0 39.9 48.9 48.7 49.7 81.8 75.2 56.7 53.8 89.9 83.4 25.2 63.0 50.2 223.2 56.7 49.0 52.6 64.1 41.6 37.0 52.9 59.5 64.4 48.2 48.1 47.9 67.7 103.3 82.0 80.8 71.5 73.9 69.2 58.8 47.7 44.3 62.4 41.3 58.1 72.7 59.1 36.1 50.5 73.1 54.3 43.4 81.8 40.1 76.2 65.9 85.7 94.3 54.3 76.0 60.6 12.9 50.9 16.6 35.4 51.1 44.9 48.7 37.8 37.5 66.4 37.8 38.0 41.4 5.0 42.7 43.1 58.0 48.7 72.8 27.6 28.5 29.0 29.7 27.7 28.7 28.6 28.2 28.9 28.0 29.6 28.3 62.4 25.6 30.4 4.2 123.3 167.0 134.8 158.7 109.8 30.1 79.5 67.7 70.2 82.9 68.0 71.7 16.7 180.0 89.7 74.8 223.0 135.3 139.6 50.5 58.8 77.1 105.1 98.8 7.3 133.2 232.1 70.4 65.7 50.6 74.3 100.3 69.9 101.4 163.9 28.6 8.4 133.5 99.7 120.2 130.7 143.2 55.3 93.3 113.8 4.7 153.2 76.1 105.0 4.5 8.7 116.2 85.2 54.5 130.3 153.4 116.2 245.9 35.2 33.7 72.3 73.3 76.9 130.1 148.2 185.5 210.3 135.6 102.6 100.9 189.7 158.7 TP53INP2 "C20orf110, dJ1181N3.1, DKFZp434B2411, DKFZp434O0827, DOR, FLJ21759, FLJ23500, PINH" ENSG00000078804 "Tumor protein p53 inducible nuclear protein 2" Q8IXH6 20 34704339-34713439 "Predicted intracellular proteins" "Autophagy, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 517.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 143.5;Early spermatids: 208.6;Late spermatids: 353.7;Paneth cells: 116.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "neutrophil: 2.7" "Lineage enriched" "Detected in single" 13 "granulocytes: 2.7" "Cell line enriched" "Detected in all" 4 "SK-BR-3: 219.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 70: Brain - Nervous system development" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (3.33e-2)" "unprognostic (2.57e-3)" "unprognostic (1.26e-1)" "unprognostic (3.08e-2)" "unprognostic (2.07e-1)" "unprognostic (1.86e-2)" "unprognostic (1.89e-1)" "unprognostic (3.03e-1)" "unprognostic (1.55e-1)" "unprognostic (6.63e-2)" "unprognostic (1.52e-2)" "unprognostic (2.57e-2)" "prognostic favorable (1.26e-8)" "unprognostic (8.03e-2)" "unprognostic (1.68e-1)" "unprognostic (1.93e-2)" "unprognostic (6.17e-2)" 19.7 28.0 315.7 11.1 439.0 89.7 13.8 343.9 403.1 19.6 159.7 42.2 19.9 26.4 15.7 64.8 19.3 23.8 85.5 233.8 348.8 31.8 45.6 19.6 5.6 517.3 444.7 15.5 16.6 35.1 22.0 10.5 464.6 36.9 38.4 45.9 27.6 31.2 53.1 12.3 23.5 34.7 418.6 6.6 24.4 39.9 376.8 2.9 31.6 94.0 17.2 33.0 23.8 485.7 2.5 3.0 9.8 12.6 22.1 18.1 4.2 9.8 30.9 12.8 10.6 17.3 1.2 7.7 6.6 19.6 25.1 1.9 20.8 4.7 14.0 2.3 2.6 14.0 8.2 16.9 28.6 2.2 10.9 52.3 7.0 10.1 1.4 16.0 20.2 6.9 5.8 24.8 14.5 3.4 1.6 4.8 1.3 2.1 7.4 7.4 6.4 12.4 16.1 8.8 21.4 24.1 8.7 219.0 15.2 11.6 15.8 10.3 15.3 35.0 12.0 4.6 4.1 9.8 12.5 6.2 22.2 31.2 12.5 0.5 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.2 0.0 0.0 315.7 439.0 343.9 403.1 233.8 348.8 517.3 444.7 464.6 418.6 376.8 485.7 9.5 3.2 10.6 5.5 8.1 3.7 17.0 11.7 5.7 20.4 17.4 12.3 75.4 15.7 16.7 3.7 52.1 1.7 12.8 143.5 5.9 16.5 208.6 19.6 10.1 10.4 52.4 0.4 4.3 23.9 1.1 9.6 46.9 24.2 7.0 7.5 11.0 28.7 5.3 32.0 6.1 59.5 32.6 10.2 3.6 353.7 7.5 15.5 5.4 2.8 2.6 10.9 0.0 1.0 17.7 24.3 116.1 13.2 7.4 15.3 34.0 8.9 25.1 55.8 19.7 35.9 27.4 4.0 2.7 4.5 3.0 28.5 8.4 9.1 23.9 24.4 TP53TG3D ENSG00000205456 "TP53 target 3D" Q9ULZ0 16 32252719-32255922 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "epididymis: 3.4;testis: 2.2" "Group enriched" "Detected in some" 6 "Early spermatids: 77.5;Late spermatids: 21.1;Spermatocytes: 32.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 1.2;HEL: 1.1;HMC-1: 1.4;RH-30: 1.1;SCLC-21H: 1.2;U-2 OS: 1.2" "HPA047832, HPA060916" Approved "Centriolar satellite" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 29: Early spermatids - Spermatogenesis" "Centriolar satellite" "HPA047832: , HPA060916: " "unprognostic (1.65e-2)" "unprognostic (1.92e-1)" "unprognostic (5.60e-2)" "unprognostic (1.57e-1)" "unprognostic (1.02e-1)" "unprognostic (1.21e-1)" "unprognostic (5.98e-3)" "unprognostic (1.47e-2)" "unprognostic (2.06e-2)" "unprognostic (1.48e-1)" "unprognostic (1.32e-1)" 0.1 0.8 0.1 0.1 0.2 0.0 0.2 0.8 0.3 0.3 0.0 0.2 0.0 0.4 3.4 0.7 0.2 0.0 0.3 0.1 0.3 0.5 0.0 0.1 0.1 0.3 0.2 0.2 0.1 0.0 0.5 0.4 0.4 0.3 0.0 0.1 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.2 0.1 2.2 0.4 0.0 0.2 0.0 0.0 0.2 0.4 0.4 0.2 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.0 1.2 0.3 0.0 0.0 0.3 0.2 0.3 0.0 0.0 0.1 1.2 0.2 0.0 0.6 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.8 0.3 0.1 0.3 0.3 0.2 0.4 0.1 0.4 0.4 0.3 0.0 0.0 0.0 0.0 0.5 0.2 0.1 0.0 0.1 0.5 0.8 0.3 0.0 0.1 0.0 2.1 0.1 0.5 0.0 0.0 0.0 77.5 0.1 1.0 0.1 0.0 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.6 21.1 1.2 0.1 5.4 0.0 0.0 0.4 0.0 0.0 0.4 0.1 0.0 1.2 0.1 0.2 0.0 0.0 0.2 0.1 6.6 0.6 0.3 32.5 6.6 0.0 0.1 0.0 0.1 0.4 0.0 0.0 TP53TG5 "C20orf10, CLG01, dJ453C12.5" ENSG00000124251 "TP53 target 5" Q9Y2B4 20 45372557-45407889 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 17.8" "Cell type enhanced" "Detected in some" "Early spermatids: 671.5;Late spermatids: 254.4;Oligodendrocytes: 157.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 2.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA041979, HPA058510, HPA077455" Enhanced Supported "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes NA "Cluster 78: Testis - Spermatogenesis" "Cluster 39: CACO-2 - Unknown function" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoli, Nucleoli rim" "Mitotic chromosome" "HPA041979: AB_2677778, HPA058510: , HPA077455: " "unprognostic (2.86e-1)" "unprognostic (1.28e-1)" "unprognostic (2.18e-1)" "unprognostic (3.40e-3)" "unprognostic (1.70e-1)" "unprognostic (1.63e-3)" "unprognostic (2.29e-3)" "unprognostic (3.10e-3)" "unprognostic (9.26e-2)" "unprognostic (3.56e-2)" "unprognostic (1.72e-5)" "unprognostic (2.09e-2)" "unprognostic (7.46e-2)" "unprognostic (1.48e-1)" "unprognostic (1.46e-1)" "unprognostic (4.72e-4)" "unprognostic (1.41e-1)" 0.1 0.1 1.1 0.2 1.8 0.7 0.1 0.9 2.6 0.1 1.4 0.3 0.1 0.2 0.4 0.1 0.2 0.2 0.2 1.1 1.5 0.1 0.1 0.2 0.4 1.8 1.5 0.1 0.1 0.0 0.2 0.1 2.0 0.1 0.0 0.8 0.2 0.0 0.2 0.2 0.2 0.0 0.7 0.2 0.2 17.8 1.7 0.0 0.2 0.0 0.0 0.2 0.1 3.5 0.3 0.7 0.4 1.1 0.0 0.0 0.3 0.2 0.0 0.0 0.0 2.1 0.3 0.3 0.2 0.0 0.2 0.8 0.0 0.0 0.0 0.1 0.3 0.4 1.0 0.6 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.4 0.1 0.0 0.5 0.4 0.3 0.1 0.3 0.3 0.0 0.2 0.2 0.0 0.4 0.4 0.3 1.0 0.4 0.2 0.1 1.1 0.1 0.6 1.4 0.4 0.9 0.2 0.3 0.4 0.0 0.7 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.8 0.9 2.6 1.1 1.5 1.8 1.5 2.0 0.7 1.7 3.5 0.1 0.0 0.0 2.9 0.0 0.1 0.4 0.0 0.0 0.8 0.5 0.3 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 671.5 0.5 0.2 0.3 0.0 0.0 7.6 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 7.8 0.5 0.0 0.0 1.1 254.4 4.7 0.1 0.0 1.9 0.0 0.1 0.0 2.5 157.5 0.0 1.2 4.5 0.0 0.2 0.2 0.1 0.3 1.0 0.0 0.4 1.2 2.1 1.8 0.0 1.1 0.0 0.1 0.0 0.3 0.9 TP63 "EEC3, KET, NBP, OFC8, p51, p53CP, p63, p73H, p73L, SHFM4, TP53CP, TP53L, TP73L" ENSG00000073282 "Tumor protein p63" Q9H3D4 3 189631389-189897276 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Apoptosis, Notch signaling pathway, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 69.6;skin 1: 137.3" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 275.4;Basal squamous epithelial cells: 335.2;Squamous epithelial cells: 173.4;Suprabasal keratinocytes: 283.1" "Group enriched" "Detected in many" 11 "cervical cancer: 37.9;head and neck cancer: 73.3;lung cancer: 37.3;urothelial cancer: 21.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HaCaT: 87.1;HBEC3-KT: 167.3;hTCEpi: 124.0;hTERT-HME1: 117.3;RT4: 185.1" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB000083, HPA006288, HPA006289, HPA007009, HPA007010" Enhanced Enhanced Nucleoplasm NA NA "Cluster 17: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 15: RT4 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "CAB000083: AB_2207187, HPA006288: AB_1080334, HPA006289: , HPA007009: , HPA007010: AB_1080336" "prognostic favorable (1.07e-4)" "unprognostic (1.30e-1)" "unprognostic (1.44e-1)" "unprognostic (3.02e-1)" "unprognostic (4.38e-2)" "unprognostic (3.50e-1)" "unprognostic (1.29e-1)" "unprognostic (5.17e-2)" "unprognostic (2.78e-1)" "unprognostic (5.37e-2)" "unprognostic (2.09e-3)" "unprognostic (1.54e-1)" "unprognostic (1.87e-5)" "unprognostic (1.86e-1)" "unprognostic (1.05e-1)" "unprognostic (1.62e-1)" "unprognostic (2.74e-3)" 0.5 0.3 0.3 0.6 0.3 0.4 18.0 0.9 0.5 23.5 0.3 0.3 0.1 0.3 10.5 69.6 1.0 0.3 0.6 0.5 0.5 0.3 0.4 1.9 1.0 0.4 0.6 0.1 0.3 0.0 0.5 10.8 0.7 17.4 0.2 0.0 20.8 18.0 42.4 137.3 0.2 0.3 0.2 0.2 0.4 3.4 0.4 23.1 0.3 12.4 17.7 18.6 54.4 0.4 2.3 4.6 0.0 0.1 0.2 0.1 1.2 0.1 0.0 0.0 0.0 0.0 0.0 16.6 0.6 0.1 0.2 87.1 0.0 167.3 0.0 1.4 0.0 1.9 1.3 0.4 0.0 0.0 0.3 0.2 124.0 0.2 117.3 0.1 0.0 0.0 0.0 0.1 0.1 0.4 0.1 0.2 0.3 0.2 0.0 1.0 0.3 0.0 0.2 185.1 0.2 0.1 0.2 0.0 0.0 2.5 0.9 0.2 0.3 0.2 0.1 0.2 0.0 25.3 0.3 1.1 0.5 0.1 0.8 0.6 0.0 0.2 0.1 0.0 0.0 0.7 0.2 0.1 0.0 0.3 0.1 0.1 0.4 0.2 0.0 0.2 0.1 0.0 0.3 0.3 0.9 0.5 0.5 0.5 0.4 0.6 0.7 0.2 0.4 0.4 0.2 0.0 5.3 1.0 0.9 275.4 26.8 61.9 335.2 0.0 0.9 30.1 0.7 0.0 8.5 0.0 0.0 24.9 0.1 0.1 0.0 0.2 1.8 0.0 0.1 1.1 0.0 0.0 1.3 0.2 2.8 1.4 0.0 0.1 0.0 0.0 0.0 0.1 2.4 0.0 4.8 0.0 2.0 0.0 11.9 0.4 0.3 0.7 8.8 14.0 0.6 0.0 0.0 0.5 1.4 1.6 0.0 1.2 1.6 5.6 0.0 0.0 2.8 0.0 0.0 5.3 0.9 0.5 2.4 173.4 283.1 8.9 0.6 0.2 0.0 15.2 TPP2 TPPII ENSG00000134900 "Tripeptidyl peptidase 2" P29144 13 102596986-102679958 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 9 "Early spermatids: 796.3;Late spermatids: 892.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021069, HPA049630" Approved Supported "Nuclear bodies,Cytosol" NA NA 280000 "Cluster 39: Non-specific - mRNA processing" "Cluster 23: Testis - Cell cycle regulation" "Cluster 32: U-937 - Innate immune response" "Cluster 25: Spermatids - Spermatogenesis" "Nuclear bodies, Cytosol" "HPA021069: AB_1858344, HPA049630: AB_2680836" "unprognostic (4.75e-2)" "unprognostic (4.78e-2)" "unprognostic (9.97e-2)" "unprognostic (1.08e-1)" "unprognostic (2.01e-2)" "unprognostic (4.43e-2)" "unprognostic (2.45e-2)" "unprognostic (8.33e-3)" "unprognostic (5.02e-2)" "unprognostic (1.51e-1)" "unprognostic (3.12e-1)" "unprognostic (2.75e-3)" "unprognostic (6.26e-2)" "unprognostic (3.12e-1)" "unprognostic (7.53e-2)" "unprognostic (3.95e-2)" "unprognostic (3.43e-3)" 12.6 8.1 3.5 15.6 5.5 48.0 16.4 9.7 5.3 12.9 5.7 13.9 12.3 16.3 19.7 11.6 11.5 12.5 13.8 3.0 2.3 10.0 20.4 14.6 19.9 3.7 3.1 14.1 10.9 11.3 8.3 17.7 4.4 11.3 19.2 17.4 10.6 16.7 27.7 12.1 12.5 13.1 3.3 18.6 12.2 51.8 4.9 16.1 19.9 22.1 17.1 12.8 11.4 9.8 33.8 13.7 38.0 28.7 28.9 37.5 25.5 34.9 26.6 23.8 28.0 30.7 41.0 37.3 11.9 30.3 25.7 30.0 30.5 23.7 39.3 26.4 24.9 71.2 34.0 22.8 22.9 89.3 44.6 31.5 11.2 26.4 35.6 23.6 32.7 34.8 43.4 42.9 32.0 11.3 37.2 53.4 28.5 43.7 17.6 43.5 30.3 31.8 25.7 29.7 35.8 26.7 23.2 35.0 13.7 31.9 20.0 79.9 28.5 20.9 15.1 12.9 29.0 40.7 56.2 37.0 31.1 56.6 26.8 7.4 5.5 3.7 7.1 5.9 8.4 4.8 8.2 8.4 5.2 4.5 9.7 9.8 1.0 8.9 4.9 3.3 9.6 4.5 3.5 5.5 9.7 5.3 3.0 2.3 3.7 3.1 4.4 3.3 4.9 9.8 20.9 38.5 41.6 41.8 24.5 15.4 16.4 10.6 22.8 27.5 18.5 12.7 41.8 11.5 18.5 14.7 73.0 28.5 38.7 13.3 9.8 19.8 796.3 23.0 28.9 19.3 19.8 26.1 64.1 8.8 30.7 25.8 14.3 22.7 38.6 24.8 20.3 22.4 32.1 8.4 69.8 18.5 8.2 25.7 19.9 892.8 32.0 29.5 17.8 65.6 29.3 13.8 42.2 66.4 67.3 13.3 16.3 18.8 58.9 16.5 10.2 13.2 36.4 46.5 26.3 24.3 28.8 92.7 30.0 22.9 13.4 33.1 35.6 31.6 21.8 19.6 TPPP2 "C14orf8, CT152, p18, p25beta" ENSG00000179636 "Tubulin polymerization promoting protein family member 2" P59282 14 21024109-21036276 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "testis: 254.8" "Cell type enriched" "Detected in some" 4 "Late spermatids: 9161.6" "Cancer enhanced" "Detected in single" "liver cancer: 0.5" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA004120 Enhanced NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 25: Spermatids - Spermatogenesis" "HPA004120: AB_2303582" "unprognostic (2.91e-2)" "unprognostic (2.49e-3)" "unprognostic (2.54e-1)" "unprognostic (1.66e-2)" "unprognostic (2.14e-2)" "unprognostic (2.57e-3)" "unprognostic (4.63e-4)" "unprognostic (3.83e-1)" "unprognostic (3.16e-1)" "unprognostic (1.09e-1)" "unprognostic (4.64e-4)" "unprognostic (2.51e-4)" "unprognostic (1.22e-1)" "unprognostic (1.06e-1)" "unprognostic (3.21e-1)" 0.1 0.4 0.8 0.1 0.9 0.0 0.5 0.8 1.1 0.2 1.3 0.1 0.1 0.2 3.4 0.0 0.2 0.3 0.6 0.8 0.8 0.9 13.3 0.1 0.0 0.9 0.8 0.8 0.2 0.2 0.1 0.0 0.9 0.4 0.3 0.3 1.4 0.2 3.2 0.1 0.3 0.0 0.9 0.1 0.1 254.8 0.9 0.0 0.1 4.7 0.0 0.1 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.9 0.8 1.1 0.8 0.8 0.9 0.8 0.9 0.9 0.9 0.8 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.3 1.9 0.0 0.0 1.8 0.0 0.0 0.0 0.1 0.0 0.1 1897.4 0.1 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 5.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 9161.6 47.5 2.7 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 35.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 52.0 30.2 0.0 0.0 0.1 0.0 0.1 0.0 0.1 TPSAB1 "TPS1, TPS2, TPSB1" ENSG00000172236 "Tryptase alpha/beta 1" Q15661 16 1240379-1242554 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 13 "granulocytes: 5873.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 893 "basophil: 89.3" "Lineage enriched" "Detected in single" 893 "granulocytes: 89.3" "Cell line enriched" "Detected in some" 166 "HMC-1: 3813.2" "CAB016369, CAB022175, HPA049153, HPA049554" Supported "Secreted to blood" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "CAB016369: AB_628406, CAB022175: , HPA049153: AB_2680656, HPA049554: AB_2680815" "unprognostic (2.06e-2)" "unprognostic (5.14e-2)" "unprognostic (2.02e-3)" "unprognostic (1.64e-2)" "unprognostic (9.31e-3)" "prognostic favorable (9.62e-6)" "unprognostic (1.02e-1)" "unprognostic (4.08e-2)" "unprognostic (1.80e-1)" "unprognostic (1.43e-1)" "unprognostic (2.24e-1)" "unprognostic (2.83e-2)" "unprognostic (4.13e-2)" "unprognostic (2.23e-1)" "unprognostic (2.81e-2)" "unprognostic (1.16e-1)" "unprognostic (1.36e-2)" 96.6 2.9 0.3 23.6 0.5 2.4 47.2 0.3 0.9 53.7 0.9 83.0 71.6 73.3 6.0 64.3 26.6 129.7 14.7 0.4 0.4 13.9 12.2 128.5 21.3 0.4 0.3 3.2 18.9 2.3 3.5 1.2 0.6 65.9 34.6 0.0 60.2 22.5 10.1 122.7 148.7 17.9 0.4 5.9 104.0 8.9 0.4 14.2 4.7 13.0 13.2 113.5 52.6 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 2.7 0.0 0.0 0.0 0.0 0.0 19.3 0.0 0.0 0.0 1.3 3813.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.3 2.1 6.1 0.5 0.4 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.1 1.1 0.0 0.0 2.8 22.9 2.0 89.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.3 0.5 0.3 0.9 0.4 0.4 0.4 0.3 0.6 0.4 0.4 0.3 0.0 25.6 135.5 0.0 2.9 18.6 5.1 0.0 1.2 0.0 0.9 0.1 0.3 0.0 8.1 0.0 0.0 0.0 0.2 0.9 0.0 1.2 0.3 0.0 0.0 4.1 0.0 3.8 0.0 0.0 0.2 7.6 0.5 0.0 5873.9 0.0 0.0 0.3 5.2 0.0 0.0 0.0 0.0 0.3 25.6 0.2 0.0 7.7 19.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 11.7 4.0 0.4 0.1 5.1 0.0 0.0 0.3 3.2 0.0 0.1 0.1 9.9 0.3 440.9 0.0 0.5 5.6 TPSB2 ENSG00000197253 "Tryptase beta 2" P20231 16 1227272-1230184 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 25 "granulocytes: 8966.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 50 "basophil: 5.0" "Lineage enriched" "Detected in single" 50 "granulocytes: 5.0" "Cell line enriched" "Detected in some" 7 "HMC-1: 297.5" "HPA049153, HPA049554" Supported "Secreted to blood" NA NA 16000000 "Cluster 10: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "HPA049153: AB_2680656, HPA049554: AB_2680815" "unprognostic (9.05e-2)" "unprognostic (8.46e-3)" "unprognostic (2.42e-3)" "unprognostic (2.27e-2)" "unprognostic (4.97e-3)" "unprognostic (1.02e-3)" "unprognostic (1.11e-1)" "unprognostic (8.55e-2)" "unprognostic (2.48e-1)" "unprognostic (2.24e-1)" "unprognostic (1.95e-1)" "unprognostic (8.30e-3)" "unprognostic (1.91e-2)" "unprognostic (5.76e-2)" "unprognostic (2.41e-2)" "unprognostic (4.65e-2)" "unprognostic (3.17e-2)" 95.1 2.5 0.3 20.2 0.6 4.3 47.8 0.3 0.9 53.2 1.0 77.8 35.5 71.8 9.8 64.6 30.4 103.9 15.0 0.5 0.5 15.5 12.2 127.8 26.2 0.5 0.4 3.5 18.9 1.5 3.9 1.3 0.5 67.0 19.8 0.0 64.5 13.3 10.0 122.5 146.1 22.0 0.5 5.2 102.1 9.9 0.5 4.9 4.7 10.4 9.9 118.6 53.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 41.2 0.0 0.0 0.2 0.4 297.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.3 4.7 0.3 1.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.7 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.3 0.9 0.5 0.5 0.5 0.4 0.5 0.5 0.5 0.3 0.1 38.5 275.3 0.0 2.8 0.0 4.4 0.0 0.0 0.0 1.5 0.0 1.5 0.0 16.7 0.0 0.0 0.1 0.6 0.7 0.0 2.4 0.6 0.0 0.0 3.2 0.0 18.9 0.0 0.0 0.2 6.0 2.0 0.0 8966.1 0.0 0.0 0.0 3.8 0.0 0.1 0.7 0.0 0.0 0.0 1.0 0.0 11.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 25.8 5.4 0.7 0.1 3.6 0.0 0.0 0.4 1.1 0.0 0.7 0.0 0.0 0.1 345.1 0.0 1.0 6.1 TPST1 TANGO13A ENSG00000169902 "Tyrosylprotein sulfotransferase 1" O60507 7 66205317-66420543 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 76.5;Excitatory neurons: 101.9;Inhibitory neurons: 107.1;Spermatocytes: 97.1" "Cancer enhanced" "Detected in all" "glioma: 36.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 52.2;neutrophil: 35.2" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047415, HPA061837" Approved Supported "Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus" "HPA047415: AB_10964056, HPA061837: AB_2732672" "unprognostic (7.46e-2)" "unprognostic (1.45e-1)" "unprognostic (8.62e-2)" "unprognostic (3.43e-2)" "unprognostic (3.52e-2)" "unprognostic (1.78e-3)" "unprognostic (5.71e-2)" "unprognostic (8.21e-2)" "unprognostic (3.59e-1)" "unprognostic (9.25e-3)" "unprognostic (4.12e-2)" "unprognostic (4.98e-1)" "prognostic unfavorable (8.16e-6)" "prognostic unfavorable (8.78e-4)" "unprognostic (2.48e-1)" "unprognostic (1.74e-2)" "prognostic unfavorable (3.73e-5)" 16.9 15.8 22.1 10.8 20.5 6.0 13.4 18.4 21.6 35.4 12.3 11.1 3.2 21.8 14.3 10.8 11.2 38.1 8.5 19.4 36.7 23.1 46.0 11.5 5.9 37.2 25.0 13.5 7.8 11.0 19.5 26.4 24.7 15.1 8.0 5.2 6.8 16.4 2.7 8.2 8.7 16.2 22.9 12.0 10.9 23.0 33.8 2.1 11.3 5.6 5.3 36.8 22.1 22.5 12.1 6.5 16.5 22.4 52.7 42.0 5.7 22.3 49.8 25.7 37.1 21.9 6.6 1.4 17.7 45.1 38.9 8.9 16.2 24.8 33.3 3.5 9.3 2.3 15.1 16.5 62.3 1.8 1.9 59.5 19.0 50.2 22.1 27.8 32.7 2.9 1.0 10.2 40.2 6.2 0.1 3.1 15.5 0.4 9.6 7.8 14.6 11.4 27.3 11.5 10.4 44.5 27.8 2.1 62.2 32.4 8.6 4.7 62.3 33.1 21.3 24.2 40.6 9.2 13.3 4.7 29.6 6.8 48.2 52.2 2.3 23.9 0.8 0.1 0.8 6.1 0.5 0.6 0.3 14.0 2.2 4.1 35.2 8.8 0.0 0.0 0.0 1.9 22.1 20.5 18.4 21.6 19.4 36.7 37.2 25.0 24.7 22.9 33.8 22.5 33.8 0.0 8.9 38.8 11.5 10.8 7.7 24.4 33.6 8.5 4.0 13.3 1.6 5.7 9.6 31.3 2.1 1.8 3.8 0.2 9.8 23.0 11.2 13.3 76.5 17.9 7.7 1.3 101.9 47.6 4.3 58.5 12.2 9.7 4.5 12.2 10.0 34.1 16.2 6.7 107.1 0.8 8.2 8.9 8.9 11.6 48.1 6.2 14.2 32.8 15.8 5.0 1.0 61.3 38.8 23.7 0.1 37.2 7.1 5.3 0.0 3.2 19.5 3.6 6.6 16.4 21.6 97.1 41.3 15.1 7.5 3.8 2.8 12.6 0.7 7.7 TPST2 TANGO13B ENSG00000128294 "Tyrosylprotein sulfotransferase 2" O60704 22 26521996-26596717 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 398.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 171.0;NK-cells: 263.7;Plasma cells: 183.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 158.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021054 Enhanced "Intracellular and membrane" NA NA 88000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 25: Pancreas - Digestion" "Cluster 3: HMC-1 - Innate immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA021054: AB_1858221" "unprognostic (2.24e-1)" "unprognostic (1.70e-1)" "unprognostic (1.74e-2)" "prognostic favorable (8.08e-5)" "unprognostic (8.88e-2)" "unprognostic (1.06e-1)" "unprognostic (1.19e-2)" "unprognostic (9.70e-2)" "unprognostic (3.18e-2)" "unprognostic (3.38e-1)" "unprognostic (2.70e-1)" "unprognostic (5.54e-2)" "prognostic unfavorable (2.34e-6)" "unprognostic (9.68e-2)" "unprognostic (9.21e-3)" "unprognostic (5.62e-2)" "unprognostic (2.01e-1)" 24.4 31.0 24.4 15.2 20.8 23.1 21.8 19.1 29.9 17.4 26.9 11.5 13.6 18.0 111.6 18.7 17.0 12.2 27.5 23.4 22.9 24.9 74.9 45.7 19.1 22.0 24.2 9.2 398.8 5.3 9.9 41.8 20.8 16.0 8.8 3.3 10.9 17.8 38.5 18.4 13.4 12.1 23.1 36.4 11.7 20.6 34.2 10.7 38.8 22.6 17.0 17.1 17.3 20.7 12.8 9.1 11.7 6.0 24.4 18.7 16.4 27.9 49.9 22.2 20.3 6.2 6.5 21.4 7.3 50.4 11.6 19.5 8.8 19.2 12.7 8.8 16.9 51.8 5.6 13.1 10.2 6.0 158.7 20.1 30.3 22.5 7.7 22.5 41.6 9.6 52.6 65.2 17.2 14.3 24.3 40.7 15.4 10.0 9.1 22.5 15.8 60.2 6.7 14.3 8.8 6.1 12.9 11.2 16.0 17.0 5.2 24.7 33.2 27.3 61.2 22.5 27.3 20.9 31.5 20.6 20.7 23.1 25.3 490.4 77.0 111.9 249.2 86.3 70.5 23.6 57.0 187.2 48.3 25.6 27.8 163.6 163.0 354.9 94.3 115.3 71.9 240.7 24.4 20.8 19.1 29.9 23.4 22.9 22.0 24.2 20.8 23.1 34.2 20.7 37.3 16.0 12.6 13.7 30.8 38.1 82.5 29.9 14.2 9.0 10.8 13.1 15.5 47.1 14.4 22.0 6.2 171.0 120.8 6.7 27.4 12.9 15.2 31.1 14.8 66.1 0.0 64.6 23.4 65.1 49.8 10.7 5.1 39.5 53.7 13.9 113.6 79.3 123.9 6.7 20.3 9.3 12.2 55.9 48.6 4.5 5.3 70.1 28.4 47.8 32.4 1.9 263.7 5.0 1.9 53.1 8.7 4.1 183.7 36.4 16.5 7.6 18.6 5.3 6.6 9.9 15.3 2.9 13.2 15.1 35.9 143.0 64.4 42.0 11.8 83.7 TPTE "CT44, PTEN2" ENSG00000274391 "Transmembrane phosphatase with tensin homology" P56180 21 10521553-10606140 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 201 "testis: 107.2" "Cell type enriched" "Detected in some" 6 "Spermatocytes: 464.7" "Cancer enriched" "Detected in single" 7 "testis cancer: 0.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 6.7;K-562: 8.2;Karpas-707: 6.4;MCF7: 4.9;PC-3: 4.8;RPMI-8226: 9.0;SuSa: 7.6;U-266/70: 7.7" "HPA049690, HPA068342" Enhanced Approved "Endoplasmic reticulum,Cytosol" NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Cytosol "Endoplasmic reticulum" "HPA049690: AB_2680850, HPA068342: AB_2685976" "unprognostic (3.63e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 107.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 6.4 0.0 4.9 0.0 0.0 1.0 0.0 4.8 0.0 0.0 9.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 7.6 0.0 0.0 0.0 1.8 4.1 2.1 0.0 7.7 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 20.6 0.1 0.0 0.1 0.0 0.0 0.7 0.0 1.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.3 13.9 5.0 0.1 0.0 1.9 0.0 0.0 0.0 0.5 0.3 0.0 0.0 2.6 0.0 0.0 0.0 0.4 0.0 0.0 13.1 0.0 0.0 464.7 69.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 TPX2 "C20orf1, C20orf2, DIL-2, p100" ENSG00000088325 "TPX2 microtubule nucleation factor" Q9ULW0 20 31739271-31801805 "Cancer-related genes, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Mitosis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 48.0;lymphoid tissue: 70.3;testis: 30.7" "Cell type enhanced" "Detected in many" "Erythroid cells: 90.7;Extravillous trophoblasts: 68.5;Granulosa cells: 46.6;Spermatocytes: 114.5;Spermatogonia: 63.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "T-reg: 8.1" "Group enriched" "Detected in many" 5 "granulocytes: 5.1;NK-cells: 3.6;T-cells: 8.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005487 Enhanced Supported "Nucleoplasm,Cytokinetic bridge,Mitotic spindle" Yes Yes "Cluster 44: Non-specific - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Cytokinetic bridge, Mitotic spindle" "HPA005487: AB_1858223" "unprognostic (2.18e-2)" "unprognostic (1.77e-1)" "unprognostic (1.97e-2)" "prognostic unfavorable (2.43e-6)" "unprognostic (2.99e-1)" "unprognostic (7.56e-2)" "prognostic unfavorable (8.07e-7)" "prognostic unfavorable (6.46e-4)" "unprognostic (3.70e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (2.68e-5)" "unprognostic (5.99e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (4.56e-2)" "unprognostic (2.30e-1)" "unprognostic (1.76e-2)" "unprognostic (1.39e-1)" 1.9 1.4 0.9 13.0 0.9 48.0 2.7 0.8 1.0 2.3 0.5 11.6 9.4 2.4 0.2 13.2 0.9 1.8 0.8 1.1 0.6 0.7 4.2 1.9 26.6 0.6 1.0 0.5 0.4 0.4 0.2 8.3 0.7 0.7 14.2 0.5 2.0 0.5 1.4 9.8 9.4 6.8 0.6 5.2 6.2 30.7 1.3 70.3 1.0 0.8 32.3 3.4 4.1 0.9 455.1 149.1 176.4 139.1 13.8 25.2 169.8 186.1 104.5 264.0 197.7 319.1 190.4 212.4 106.7 104.5 196.8 232.7 203.7 169.0 298.8 92.3 78.8 416.3 139.7 219.6 4.2 161.9 102.8 8.7 9.1 166.0 120.0 37.9 144.6 157.1 313.8 187.8 209.7 186.2 272.2 125.3 197.1 174.0 159.3 152.5 475.5 128.2 71.2 72.8 127.5 85.7 284.6 106.3 82.0 120.9 185.1 97.3 98.3 294.1 179.7 136.5 290.0 74.4 138.6 187.3 92.2 565.1 195.8 5.1 0.0 0.4 0.4 0.0 0.2 0.6 1.4 1.7 0.5 0.2 0.3 0.5 0.2 3.6 0.1 1.0 8.1 1.0 0.9 0.9 0.8 1.0 1.1 0.6 0.6 1.0 0.7 0.6 1.3 0.9 1.0 0.0 4.2 0.0 5.9 6.9 1.5 4.3 1.2 0.9 3.0 3.4 0.9 4.3 3.8 0.0 0.0 23.3 3.8 6.4 0.0 1.2 9.3 7.3 6.6 3.9 1.2 90.7 2.9 0.4 68.5 9.2 16.3 8.4 0.0 46.6 8.9 3.0 19.5 1.7 0.9 9.8 10.2 8.0 5.5 13.1 0.9 7.6 0.0 1.0 2.1 0.4 3.1 0.5 0.5 1.8 1.4 0.0 30.8 2.5 0.9 0.0 0.7 0.4 0.0 1.1 15.4 114.5 63.1 31.2 6.1 4.7 8.2 4.2 18.4 2.9 TRAF5 RNF84 ENSG00000082512 "TNF receptor associated factor 5" O00463 1 211326615-211374946 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "B-cells: 75.9;Early spermatids: 55.0;Late spermatids: 47.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 36.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA008052, CAB010277" Enhanced Supported Centrosome,Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 3: T-cells - Adaptive immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 57: B-cells - Immune response" Cytosol Centrosome "CAB010277: AB_2287961, HPA008052: AB_1858230" "unprognostic (6.44e-2)" "unprognostic (1.05e-1)" "unprognostic (8.15e-2)" "unprognostic (1.55e-2)" "unprognostic (1.04e-1)" "unprognostic (3.39e-2)" "unprognostic (6.44e-3)" "unprognostic (7.94e-3)" "unprognostic (1.39e-1)" "unprognostic (1.75e-1)" "unprognostic (5.92e-2)" "unprognostic (1.22e-1)" "prognostic unfavorable (2.94e-10)" "unprognostic (3.72e-1)" "unprognostic (1.34e-1)" "unprognostic (1.71e-2)" "prognostic favorable (7.29e-5)" 8.6 3.3 3.6 17.0 4.6 4.1 6.0 1.5 3.2 10.8 26.3 14.0 5.0 17.3 7.4 5.6 17.8 8.1 3.5 3.6 2.2 5.0 1.8 5.7 29.7 2.7 2.7 6.2 21.3 1.6 2.9 5.4 2.8 9.0 9.5 0.7 7.5 10.8 1.5 2.8 17.4 20.0 2.2 16.7 9.3 6.9 3.1 13.5 3.0 2.6 27.2 13.5 6.5 2.4 6.2 4.5 7.9 7.1 6.8 4.9 2.8 8.6 10.3 12.2 10.8 2.2 11.9 18.8 4.8 13.6 6.2 1.2 15.1 1.4 6.1 36.3 5.4 0.9 7.1 0.0 9.9 3.0 13.3 5.8 2.7 6.6 2.0 18.4 8.6 16.3 7.6 8.7 3.4 4.8 8.3 3.4 9.5 9.7 3.8 12.6 11.0 17.6 9.3 4.3 14.0 14.6 6.4 0.3 18.3 29.2 4.4 0.3 5.4 7.9 6.1 2.7 9.8 2.4 3.8 20.0 2.1 0.0 3.0 13.8 0.3 0.4 9.2 0.3 17.3 22.2 11.6 12.5 1.5 19.6 10.2 10.2 0.7 21.3 0.5 1.1 17.7 7.4 3.6 4.6 1.5 3.2 3.6 2.2 2.7 2.7 2.8 2.2 3.1 2.4 15.2 12.8 7.2 3.3 75.9 3.7 4.0 2.7 9.6 2.5 13.9 13.7 2.5 0.0 6.8 11.0 0.0 9.5 31.0 3.6 0.0 0.9 55.0 5.3 23.6 9.0 14.8 4.6 13.4 9.8 2.2 16.9 16.8 8.1 15.2 5.3 6.1 0.3 10.0 0.0 14.1 11.4 4.1 4.8 12.6 47.9 14.3 17.3 8.8 20.6 16.3 1.0 32.0 7.5 2.8 7.1 11.4 27.4 11.3 3.4 1.8 0.8 8.6 0.7 13.1 7.3 29.1 3.8 2.7 4.4 4.0 1.4 41.6 5.0 14.3 2.6 TRAM2 KIAA0057 ENSG00000065308 "Translocation associated membrane protein 2" Q15035 6 52497408-52577060 "Predicted membrane proteins, Transporters" "Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 122.0;Plasma cells: 69.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "ASC diff: 250.1;ASC TERT1: 265.8;fHDF/TERT166: 253.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA035092, HPA057925" Approved Approved Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 28: Placenta - Pregnancy" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" Cytosol "HPA035092: AB_10610562, HPA057925: AB_2683557" "unprognostic (2.32e-2)" "unprognostic (2.19e-1)" "unprognostic (1.72e-1)" "prognostic unfavorable (1.88e-4)" "unprognostic (1.12e-1)" "unprognostic (4.07e-2)" "unprognostic (8.90e-3)" "unprognostic (1.14e-1)" "unprognostic (1.65e-1)" "unprognostic (3.03e-1)" "unprognostic (3.01e-1)" "unprognostic (5.05e-1)" "prognostic unfavorable (1.41e-9)" "unprognostic (1.37e-2)" "unprognostic (1.60e-1)" "unprognostic (6.64e-2)" "unprognostic (1.19e-2)" 19.5 4.9 3.4 14.8 4.7 5.3 13.8 3.0 4.3 14.9 7.8 12.5 14.0 13.1 11.5 5.6 13.5 17.3 10.4 3.0 3.3 7.4 16.2 14.1 7.5 4.3 3.5 12.4 7.0 2.8 3.9 35.8 3.6 6.0 14.7 3.9 6.4 5.8 3.6 11.5 12.6 17.5 3.3 19.2 9.5 13.3 4.4 4.5 12.4 5.9 13.3 13.3 9.6 3.3 45.4 19.8 22.7 22.6 250.1 265.8 39.8 130.0 130.8 106.7 98.2 43.2 9.2 11.0 21.4 253.4 76.0 10.0 14.9 81.3 133.6 24.8 8.0 24.1 20.5 54.9 71.3 6.2 13.1 97.4 8.0 93.5 41.2 155.1 124.1 9.1 15.1 78.4 154.5 16.2 8.9 17.7 10.4 17.9 8.8 10.9 59.8 91.0 25.3 7.5 5.5 8.7 29.9 13.2 31.6 47.7 20.6 12.9 198.8 177.6 38.4 65.0 72.1 53.4 97.7 31.1 64.7 16.1 110.8 0.1 1.0 1.0 0.9 1.1 0.5 1.2 0.7 0.5 1.1 0.8 0.3 0.6 0.2 0.7 2.1 0.5 0.2 0.7 3.4 4.7 3.0 4.3 3.0 3.3 4.3 3.5 3.6 3.3 4.4 3.3 12.8 6.4 3.2 6.8 15.9 8.2 2.8 8.5 3.4 3.1 4.0 5.1 9.9 4.3 4.1 7.3 25.0 36.2 6.6 7.8 3.9 3.6 38.3 4.0 28.9 17.9 9.0 8.6 12.0 3.2 30.8 26.2 6.1 5.0 2.5 34.0 19.6 36.1 15.7 5.0 9.2 19.6 6.1 12.0 6.9 122.0 20.8 5.7 26.6 13.1 4.3 1.8 8.2 3.5 3.1 6.2 1.7 23.3 69.5 2.8 7.0 3.1 4.9 12.7 13.1 16.2 15.7 23.4 8.6 1.2 4.1 20.7 6.0 14.3 5.7 1.5 TRAPPC1 "BET5, MUM2" ENSG00000170043 "Trafficking protein particle complex 1" Q9Y5R8 17 7930345-7932123 "Predicted intracellular proteins" "ER-Golgi transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052398 Approved NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 3: Monocytes - Immune response regulation" "HPA052398: AB_2681813" "unprognostic (1.07e-1)" "unprognostic (3.89e-3)" "unprognostic (1.49e-2)" "unprognostic (7.81e-3)" "unprognostic (1.20e-2)" "unprognostic (3.58e-2)" "unprognostic (1.93e-1)" "unprognostic (2.87e-1)" "unprognostic (1.59e-1)" "unprognostic (9.86e-2)" "unprognostic (1.83e-2)" "unprognostic (1.88e-1)" "unprognostic (1.31e-2)" "unprognostic (2.22e-2)" "unprognostic (1.71e-1)" "unprognostic (8.06e-2)" "unprognostic (2.64e-1)" 111.7 145.2 130.1 91.9 128.2 100.6 100.8 133.8 142.5 99.3 124.8 119.5 83.0 129.8 124.8 156.7 94.0 74.4 169.6 129.1 139.2 158.7 123.6 132.4 140.5 136.4 134.0 79.7 101.1 109.4 124.3 114.6 134.1 93.7 87.9 67.5 103.7 65.8 139.1 110.1 121.9 102.4 127.5 170.7 118.0 72.6 145.6 166.0 101.4 94.4 153.0 108.9 104.6 134.2 178.9 306.2 161.1 186.5 262.9 258.9 101.5 221.7 233.9 206.2 233.3 172.3 104.1 192.0 164.7 337.5 203.1 159.6 173.8 282.3 235.9 279.3 278.6 93.4 165.5 193.6 196.0 114.3 243.0 302.5 197.9 218.6 162.2 262.2 240.4 174.3 74.9 130.4 314.4 166.7 246.3 157.9 101.2 130.4 138.6 122.7 137.7 165.5 392.3 131.0 68.4 165.7 150.6 78.3 166.5 217.3 163.8 124.2 271.5 146.6 105.3 138.0 179.9 139.6 130.9 100.2 294.5 132.4 176.5 315.1 235.5 427.0 190.0 225.2 157.4 243.2 189.5 196.8 270.7 215.8 158.4 177.2 244.3 192.5 235.5 293.0 288.7 304.6 130.1 128.2 133.8 142.5 129.1 139.2 136.4 134.0 134.1 127.5 145.6 134.2 90.4 67.3 46.7 11.4 160.1 54.0 81.2 257.4 78.0 32.8 120.1 158.7 13.0 131.5 124.3 240.9 8.4 375.1 182.9 135.1 340.4 280.8 33.6 60.5 76.3 97.5 118.1 105.2 10.1 259.0 427.6 84.2 67.2 74.1 102.1 78.0 153.8 136.1 362.8 45.4 9.9 155.1 193.3 210.5 135.3 72.6 115.5 195.9 149.4 8.4 374.8 97.8 303.8 6.0 15.5 256.6 162.0 83.5 120.1 62.9 200.0 530.3 87.6 33.7 39.5 31.8 117.1 67.8 69.3 139.5 72.6 271.4 169.7 113.0 144.3 100.2 TRAPPC10 "EHOC-1, TMEM1, TRS130" ENSG00000160218 "Trafficking protein particle complex 10" P48553 21 44012309-44106552 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 81.2;Oligodendrocytes: 132.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 11 "basophil: 9.7" "Lineage enriched" "Detected in single" 13 "granulocytes: 9.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050423 Supported NA NA "Cluster 34: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 63: NK-cells & T-cells - Immune response" "HPA050423: AB_2681123" "unprognostic (1.82e-2)" "unprognostic (4.89e-3)" "unprognostic (3.52e-2)" "unprognostic (2.72e-1)" "unprognostic (3.79e-1)" "unprognostic (2.95e-3)" "unprognostic (1.93e-1)" "unprognostic (4.00e-1)" "unprognostic (9.70e-2)" "unprognostic (3.07e-3)" "unprognostic (2.60e-1)" "unprognostic (2.23e-1)" "unprognostic (3.02e-2)" "unprognostic (1.54e-1)" "unprognostic (1.41e-1)" "unprognostic (5.80e-2)" "unprognostic (2.76e-1)" 5.6 4.3 2.8 7.3 5.7 17.4 4.6 4.1 4.7 4.9 3.5 7.0 5.3 5.1 7.8 5.6 5.3 5.4 4.8 3.1 4.2 7.0 6.1 5.8 10.0 4.6 4.8 3.6 5.0 7.5 3.4 6.0 5.5 3.8 7.4 6.1 5.3 4.1 6.2 5.5 6.7 5.3 3.5 7.5 6.8 7.6 4.8 10.1 7.0 5.6 11.9 5.3 4.2 10.5 12.1 5.8 8.7 6.0 15.7 8.0 8.7 10.8 10.7 10.9 11.5 12.8 6.8 15.1 3.6 10.5 20.7 5.6 8.5 11.7 16.0 9.8 8.2 20.7 6.2 4.8 7.2 14.0 12.1 6.3 12.4 14.0 11.0 8.3 12.3 9.3 15.4 15.7 18.4 8.6 8.0 6.7 10.1 8.8 8.8 8.9 5.7 12.4 6.1 8.2 12.4 7.2 9.8 10.8 10.1 4.5 5.9 11.9 12.9 11.2 7.6 12.8 10.5 14.8 14.3 10.8 6.9 13.2 8.7 9.7 0.4 0.9 0.6 0.6 0.1 0.3 0.7 0.6 0.3 0.5 0.3 0.5 0.8 0.4 0.7 0.7 0.0 0.2 2.8 5.7 4.1 4.7 3.1 4.2 4.6 4.8 5.5 3.5 4.8 10.5 17.1 0.0 3.6 26.1 28.9 16.6 12.5 6.9 4.6 29.2 12.0 9.4 10.0 4.3 5.5 12.9 39.6 4.2 81.2 25.1 9.8 1.8 14.3 19.7 20.2 10.6 8.3 4.2 35.8 2.2 4.3 9.5 10.2 29.8 8.2 11.7 10.4 11.1 7.5 18.5 33.3 11.0 10.2 9.4 19.1 33.8 7.8 17.6 12.4 32.8 10.3 11.3 65.9 24.6 132.9 4.8 15.7 7.2 28.0 13.1 7.9 12.4 12.0 39.4 0.0 17.4 13.1 25.4 20.6 5.5 23.3 7.7 37.0 23.1 11.5 19.5 TRAPPC5 "MGC52424, TRS31" ENSG00000181029 "Trafficking protein particle complex 5" Q8IUR0 19 7680833-7687703 "Predicted intracellular proteins" "ER-Golgi transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 57.5;Gastric mucus-secreting cells: 86.2;Plasma cells: 76.9;Squamous epithelial cells: 80.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "PC-3: 314.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042221, HPA049064" Uncertain Approved Vesicles NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 43: Testis - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 59: Non-specific - Transcription" Vesicles "HPA042221: AB_2677907, HPA049064: AB_2680618" "unprognostic (3.10e-2)" "unprognostic (5.09e-2)" "unprognostic (1.45e-1)" "unprognostic (1.12e-2)" "unprognostic (1.14e-1)" "unprognostic (3.21e-3)" "unprognostic (1.80e-1)" "unprognostic (2.86e-1)" "unprognostic (6.28e-2)" "unprognostic (2.55e-2)" "unprognostic (2.12e-2)" "unprognostic (6.82e-2)" "unprognostic (4.86e-8)" "unprognostic (3.09e-1)" "unprognostic (1.11e-1)" "unprognostic (6.08e-2)" "unprognostic (1.51e-1)" 58.9 86.8 65.7 25.6 68.7 62.7 58.4 67.1 112.6 55.6 60.6 53.0 27.6 52.1 8.1 85.6 44.7 13.8 105.1 69.4 74.7 75.7 99.7 35.9 23.4 64.5 68.9 50.1 67.1 19.9 58.4 19.1 70.5 71.1 8.4 9.0 64.8 17.2 112.4 90.6 48.5 11.5 64.3 60.6 57.5 181.4 65.9 16.8 56.0 27.3 12.2 55.5 56.2 64.4 61.0 129.4 20.7 56.9 16.3 24.1 62.1 47.1 33.8 45.3 46.1 76.9 41.2 62.9 92.0 32.7 25.8 55.2 13.0 47.2 8.9 48.3 199.2 23.7 86.7 163.7 56.8 42.1 45.3 40.0 61.9 34.6 15.8 15.4 57.6 64.3 34.3 89.3 22.3 190.7 72.3 148.8 66.1 27.1 314.1 46.6 28.8 91.1 50.7 142.8 54.1 47.0 40.1 74.6 69.1 7.1 60.1 44.3 58.8 54.2 44.9 103.3 47.7 80.8 44.2 44.3 75.3 51.2 74.2 207.5 373.4 151.4 116.7 394.1 112.3 313.7 145.0 129.3 442.0 289.2 141.7 124.7 518.4 97.4 365.5 188.8 222.5 329.3 65.7 68.7 67.1 112.6 69.4 74.7 64.5 68.9 70.5 64.3 65.9 64.4 1.8 3.2 3.6 15.3 36.1 1.9 1.2 2.4 57.5 5.1 6.3 4.2 1.0 1.5 5.1 5.5 2.1 3.5 1.2 26.7 0.0 26.9 13.3 3.8 4.8 5.6 11.4 41.0 13.5 19.3 5.3 14.3 86.2 3.7 1.3 2.0 8.2 13.4 9.9 8.4 16.4 15.7 0.0 18.8 3.3 44.4 1.5 52.2 1.8 11.2 17.0 1.5 4.1 11.6 22.8 19.8 26.3 3.4 76.9 1.9 28.0 9.2 2.6 4.8 0.0 1.4 8.4 5.0 1.2 80.1 1.7 3.4 18.0 2.7 14.1 1.5 TRBV5-1 "TCRBV5S1, TCRBV5S1A1T, TRBV51" ENSG00000211734 "T cell receptor beta variable 5-1" A0A578 7 142320677-142321544 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "lymphoid tissue: 44.0" "Cell type enriched" "Detected in some" 11 "T-cells: 13.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 211.6;T-reg: 295.5" "Lineage enriched" "Detected in many" 111 "T-cells: 295.5" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (2.26e-4)" "unprognostic (1.36e-3)" "unprognostic (2.59e-2)" "unprognostic (1.49e-3)" "unprognostic (6.65e-2)" "unprognostic (7.02e-5)" "unprognostic (2.55e-2)" "unprognostic (3.66e-2)" "unprognostic (4.29e-3)" "unprognostic (5.85e-4)" "unprognostic (3.55e-2)" "unprognostic (4.36e-1)" "unprognostic (5.96e-7)" "unprognostic (2.63e-1)" "unprognostic (2.52e-2)" "unprognostic (4.06e-2)" "unprognostic (2.97e-2)" 0.3 0.0 0.0 4.8 0.0 1.1 0.2 0.0 0.0 0.4 0.0 0.7 1.0 0.1 0.0 0.1 0.1 0.8 0.0 0.0 0.0 0.1 0.2 0.7 9.9 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.2 0.0 0.0 0.3 1.9 0.1 0.0 2.6 1.6 0.2 0.0 44.0 0.2 0.0 8.9 1.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.3 2.6 0.2 11.0 0.4 166.1 65.4 0.4 0.4 211.6 128.7 2.6 0.5 0.5 0.3 295.5 82.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.1 0.0 0.0 0.0 TRBV5-6 "TCRBV5S2, TCRBV5S6, TRBV56" ENSG00000211728 "T cell receptor beta variable 5-6" A0A599 7 142500028-142500534 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 19 "lymphoid tissue: 33.8" "Group enriched" "Detected in some" 21 "Early spermatids: 13.5;Late spermatids: 14.6;T-cells: 3.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 14 "memory CD4 T-cell: 40.2;memory CD8 T-cell: 22.9;naive CD4 T-cell: 35.9;naive CD8 T-cell: 45.2;T-reg: 66.0" "Lineage enriched" "Detected in many" 56 "T-cells: 66.0" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (6.27e-3)" "unprognostic (8.46e-3)" "unprognostic (1.20e-1)" "unprognostic (7.21e-2)" "unprognostic (5.25e-1)" "unprognostic (3.45e-4)" "unprognostic (5.72e-2)" "unprognostic (6.24e-2)" "unprognostic (1.57e-2)" "unprognostic (1.46e-3)" "unprognostic (2.64e-2)" "unprognostic (2.39e-1)" "unprognostic (2.26e-7)" "unprognostic (7.62e-2)" "unprognostic (3.14e-2)" "unprognostic (2.41e-1)" "unprognostic (1.34e-1)" 0.2 0.0 0.0 2.1 0.0 0.7 0.3 0.0 0.1 0.5 0.0 0.6 0.3 0.0 0.0 0.1 0.1 0.6 0.0 0.0 0.0 0.1 0.1 0.8 7.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.1 0.3 0.0 0.2 1.1 0.1 0.0 1.9 0.4 1.7 0.0 33.8 0.1 0.1 5.8 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.9 0.0 3.0 0.1 40.2 22.9 0.1 0.1 35.9 45.2 1.1 0.0 0.1 0.2 66.0 17.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 TRBV7-1 "TCRBV6S7P, TCRBV7S1, TRBV71" ENSG00000211707 "T cell receptor beta variable 7-1 (non-functional)" 7 142332182-142332701 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 8.1" "Group enriched" "Detected in some" 280 "Early spermatids: 75.2;Late spermatids: 36.8" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "memory CD4 T-cell: 2.0;naive CD4 T-cell: 1.8;T-reg: 2.8" "Lineage enriched" "Detected in single" 29 "T-cells: 2.8" "Cell line enriched" "Detected in single" 5 "SCLC-21H: 1.8" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 29: Early spermatids - Spermatogenesis" "unprognostic (1.38e-1)" "unprognostic (2.62e-2)" "unprognostic (1.77e-1)" 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 8.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.0 0.6 0.0 0.0 1.8 0.2 0.0 0.0 0.0 0.0 2.8 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 75.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 36.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TRBV7-3 "TCRBV6S1A1N1, TCRBV7S3, TRBV73" ENSG00000211714 "T cell receptor beta variable 7-3" 7 142384329-142384841 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 6.9;testis: 2.7" "Group enriched" "Detected in some" 9 "Early spermatids: 32.5;Late spermatids: 39.8" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "memory CD4 T-cell: 31.9" "Lineage enriched" "Detected in single" 48 "T-cells: 31.9" "Cell line enhanced" "Detected in some" "ASC diff: 1.4;HBF TERT88: 2.3;HL-60: 1.6;RPTEC TERT1: 7.4;U-937: 3.8" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 58: T-cells - T-cell receptor" "unprognostic (3.78e-3)" "unprognostic (5.75e-4)" "unprognostic (1.76e-2)" "unprognostic (2.64e-3)" "unprognostic (3.07e-1)" "unprognostic (1.28e-4)" "unprognostic (4.17e-3)" "unprognostic (2.34e-2)" "unprognostic (2.06e-1)" "unprognostic (4.49e-3)" "unprognostic (8.36e-2)" "unprognostic (1.07e-1)" "unprognostic (5.57e-3)" "unprognostic (1.67e-1)" "unprognostic (1.21e-1)" "unprognostic (3.72e-1)" "unprognostic (3.10e-1)" 0.3 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.1 0.2 0.0 0.4 0.6 0.0 0.0 0.9 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.6 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 1.5 0.0 0.0 1.9 0.2 2.7 0.0 6.9 0.2 0.0 0.9 0.3 0.2 0.0 0.0 0.0 0.0 0.0 1.4 0.4 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.8 0.1 0.0 0.1 2.3 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.1 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.8 0.0 0.1 0.6 0.0 1.9 0.1 3.6 0.0 31.9 7.8 0.5 0.6 7.3 9.9 0.0 0.0 0.0 0.4 16.4 5.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 32.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.8 0.3 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 3.7 0.1 0.0 0.0 TREM2 "TREM-2, Trem2a, Trem2b, Trem2c" ENSG00000095970 "Triggering receptor expressed on myeloid cells 2" Q9NZC2 6 41158506-41163186 "Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Receptor "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 69.8;lung: 30.1" "Cell type enriched" "Detected in many" 8 "Hofbauer cells: 1014.1" "Cancer enhanced" "Detected in all" "glioma: 93.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 2.0" "Lineage enhanced" "Detected in single" "dendritic cells: 2.0" "Group enriched" "Detected in some" 4 "hTCEpi: 74.6;THP-1: 42.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010917, HPA012571" Approved "Secreted in brain" NA NA 50000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" "HPA010917: AB_1080365, HPA012571: AB_1858260" "unprognostic (3.89e-1)" "unprognostic (4.44e-3)" "unprognostic (2.77e-2)" "unprognostic (1.80e-2)" "unprognostic (1.29e-1)" "unprognostic (1.53e-1)" "prognostic unfavorable (4.24e-4)" "unprognostic (4.83e-2)" "unprognostic (1.07e-1)" "unprognostic (8.57e-3)" "unprognostic (1.33e-1)" "unprognostic (2.09e-1)" "unprognostic (3.58e-3)" "unprognostic (8.04e-2)" "unprognostic (1.04e-2)" "unprognostic (3.16e-3)" "unprognostic (1.85e-2)" 10.7 13.2 28.1 3.5 31.1 0.2 9.8 33.7 61.5 6.5 29.1 3.5 0.9 1.6 2.3 0.6 7.4 9.7 2.1 27.5 32.3 1.3 2.3 30.1 2.6 44.5 34.4 2.4 3.9 7.4 3.9 10.7 42.7 2.0 4.3 1.9 6.0 3.1 0.4 0.5 1.4 4.5 46.7 0.5 2.5 0.7 43.5 1.8 1.7 0.0 0.4 4.5 0.6 69.8 0.0 0.3 0.0 0.0 0.1 0.3 0.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.5 0.0 0.0 0.0 0.4 0.0 0.8 0.0 0.0 0.0 1.2 74.6 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 42.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 28.1 31.1 33.7 61.5 27.5 32.3 44.5 34.4 42.7 46.7 43.5 69.8 1.8 6.4 7.5 0.0 0.7 0.8 0.2 79.8 0.0 0.3 1.8 58.8 0.1 1.5 9.6 0.0 0.0 5.0 0.4 0.0 0.0 0.0 0.6 0.0 0.1 10.4 0.0 0.0 0.0 0.0 4.9 1.2 0.0 0.0 2.5 0.0 2.2 0.2 1014.1 0.0 0.0 0.0 2.0 34.7 5.2 1.0 0.6 120.5 0.0 12.2 8.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 3.3 1.0 6.6 0.1 1.0 0.0 0.0 0.0 0.1 7.3 0.8 0.0 0.0 0.1 TRERF1 "BCAR2, dJ139D8.5, HSA277276, RAPA, TReP-132" ENSG00000124496 "Transcriptional regulating factor 1" Q96PN7 6 42224931-42452051 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 96.9;Inhibitory neurons: 111.4;Microglial cells: 52.5;Oligodendrocyte precursor cells: 80.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 144.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA027771, HPA051273, HPA059943" Enhanced Enhanced "Nucleoplasm,Nucleoli fibrillar center,Cytosol" No No "Cluster 49: Eosinophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 44: HDLM-2 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Nucleoli fibrillar center, Cytosol" "HPA027771: AB_2672381, HPA051273: AB_2681416, HPA059943: AB_2684173" "unprognostic (5.85e-3)" "unprognostic (4.38e-2)" "unprognostic (2.39e-1)" "unprognostic (3.28e-3)" "unprognostic (6.64e-2)" "unprognostic (3.92e-3)" "unprognostic (1.19e-1)" "unprognostic (1.58e-2)" "unprognostic (2.05e-4)" "unprognostic (2.67e-1)" "unprognostic (1.16e-2)" "unprognostic (1.97e-2)" "prognostic unfavorable (3.67e-5)" "unprognostic (8.60e-2)" "unprognostic (5.39e-2)" "unprognostic (6.05e-2)" "unprognostic (2.78e-2)" 3.4 5.7 1.3 5.8 2.2 13.9 2.6 1.1 3.8 7.7 0.0 3.7 3.2 6.0 2.9 8.8 5.1 3.9 1.8 0.8 0.6 2.9 1.0 2.9 7.7 0.3 0.7 7.1 1.6 3.9 3.5 2.6 0.0 5.4 3.4 2.0 2.3 3.6 1.1 6.4 4.7 3.9 0.2 7.2 4.2 6.0 1.6 10.3 2.0 1.2 5.0 7.0 8.0 0.8 13.7 9.4 10.3 13.2 4.7 10.4 14.5 10.2 16.2 11.4 9.4 0.1 7.1 12.7 2.2 15.5 15.6 16.2 13.2 12.6 9.1 144.3 1.0 13.7 8.0 0.0 3.2 25.4 42.1 4.3 17.3 10.2 4.1 10.3 0.0 8.5 0.1 4.1 5.0 3.0 6.6 42.9 11.3 10.1 9.6 11.8 0.8 4.7 6.7 16.7 8.3 4.4 6.1 0.2 1.0 5.6 5.9 34.1 4.5 6.5 7.5 10.7 2.9 1.7 9.5 13.7 4.4 22.7 0.1 1.1 0.6 4.6 1.5 0.2 1.4 0.2 1.1 1.3 0.7 0.0 0.9 1.0 2.0 1.5 0.1 0.6 1.2 0.7 1.3 2.2 1.1 3.8 0.8 0.6 0.3 0.7 0.0 0.2 1.6 0.8 2.7 3.2 1.3 37.9 3.6 8.3 2.9 3.2 6.2 9.9 4.1 2.5 1.9 1.5 5.9 5.5 0.0 3.4 20.9 8.4 0.0 1.8 2.7 3.3 16.2 5.4 3.0 0.4 96.9 1.0 0.9 11.8 11.2 1.7 12.0 14.7 6.4 0.3 2.6 8.4 111.4 2.1 4.1 4.7 10.4 3.2 14.0 8.0 3.6 52.5 7.9 4.2 12.3 80.4 3.8 1.2 2.5 22.2 7.2 1.6 1.0 0.2 8.5 0.5 26.3 4.4 7.9 10.0 7.4 23.5 7.4 1.2 18.0 4.2 3.8 4.3 TRIM16 EBBP ENSG00000221926 "Tripartite motif containing 16" O95361 17 15627960-15684311 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 145.9" "Cell type enhanced" "Detected in many" "Pancreatic endocrine cells: 153.4;Squamous epithelial cells: 95.5;Urothelial cells: 111.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 9 "T-reg: 45.1" "Lineage enriched" "Detected in many" 12 "T-cells: 45.1" "Cell line enhanced" "Detected in all" "A549: 283.8;HaCaT: 229.0;HeLa: 203.8;OE19: 364.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA023623, HPA066431" Uncertain Supported "Plasma membrane,Cytosol" NA NA 19000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol "Plasma membrane" "HPA023623: AB_1858273, HPA066431: AB_2685668" "unprognostic (2.14e-1)" "unprognostic (1.95e-1)" "unprognostic (9.61e-2)" "unprognostic (1.31e-2)" "unprognostic (6.19e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (3.94e-4)" "unprognostic (1.94e-3)" "unprognostic (3.75e-2)" "unprognostic (4.65e-1)" "unprognostic (3.31e-3)" "unprognostic (1.70e-1)" "unprognostic (2.16e-3)" "unprognostic (2.08e-1)" "unprognostic (8.48e-2)" "unprognostic (9.21e-3)" "prognostic unfavorable (6.71e-4)" 18.3 32.7 14.1 7.8 16.2 17.4 13.4 17.7 21.5 44.9 10.3 14.1 22.8 6.1 4.9 145.9 8.8 16.3 23.1 13.5 15.8 8.5 5.9 14.5 9.7 16.9 16.0 7.3 6.0 3.6 4.4 34.5 17.2 10.2 11.2 3.6 38.0 11.7 28.1 44.9 12.5 9.0 15.8 6.0 31.7 12.7 17.2 10.1 18.7 27.2 37.3 35.7 70.2 22.1 91.5 283.8 8.6 19.4 40.4 46.1 9.6 14.8 51.9 17.9 25.0 17.2 115.6 9.8 54.7 64.7 106.9 229.0 25.6 65.7 12.0 120.0 16.4 4.5 203.8 9.5 67.1 5.4 9.6 25.7 40.9 39.3 22.3 49.6 38.8 11.4 5.7 45.8 49.2 32.2 20.2 11.7 13.1 364.2 17.0 8.7 71.8 6.9 92.4 116.0 6.4 17.7 64.7 72.2 22.1 49.7 10.9 12.6 61.0 22.5 26.3 10.9 51.3 11.1 12.9 1.0 34.6 12.6 58.3 0.4 3.8 1.0 1.2 1.1 0.8 0.5 4.9 1.5 2.6 0.6 1.3 2.6 0.6 0.9 0.5 0.4 45.1 2.3 14.1 16.2 17.7 21.5 13.5 15.8 16.9 16.0 17.2 15.8 17.2 22.1 34.9 38.5 2.6 14.0 5.3 30.8 59.0 55.6 10.2 7.2 11.8 5.7 12.5 10.0 73.5 11.0 18.8 13.6 2.8 9.9 0.0 49.1 1.1 16.5 9.9 28.7 4.2 9.0 9.6 17.3 8.4 9.6 34.7 25.7 4.5 12.4 3.6 3.2 4.0 3.3 14.0 21.7 28.5 2.9 8.6 3.9 7.2 2.9 7.2 11.2 13.0 6.6 4.1 18.6 19.2 153.4 26.9 4.5 3.7 29.5 4.3 6.2 33.5 8.4 6.6 5.8 14.0 10.3 12.1 95.5 77.6 4.7 5.9 60.9 18.4 111.9 TRIM17 "RBCC, RNF16, terf" ENSG00000162931 "Tripartite motif containing 17" Q9Y577 1 228407935-228416861 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "testis: 42.0" "Group enriched" "Detected in some" 27 "Early spermatids: 291.1;Late spermatids: 87.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 4.4;HEL: 2.1;NTERA-2: 1.9;SH-SY5Y: 2.3;T-47d: 5.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" HPA054908 Approved Approved Vesicles NA NA "Cluster 24: B-cells - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 6: T47d - Mammary gland" "Cluster 29: Early spermatids - Spermatogenesis" Vesicles "HPA054908: AB_2682638" "prognostic favorable (1.86e-4)" "unprognostic (2.12e-1)" "unprognostic (3.06e-2)" "unprognostic (5.45e-2)" "unprognostic (1.25e-1)" "unprognostic (7.74e-3)" "unprognostic (7.42e-3)" "unprognostic (2.02e-1)" "unprognostic (1.17e-2)" "unprognostic (8.91e-2)" "unprognostic (2.23e-1)" "unprognostic (2.04e-1)" "unprognostic (5.96e-4)" "unprognostic (3.88e-1)" "unprognostic (4.88e-2)" "unprognostic (6.33e-2)" "unprognostic (3.64e-1)" 2.1 1.2 3.2 0.3 6.3 0.2 2.9 10.2 4.9 3.0 1.1 0.6 0.2 2.0 0.4 1.9 3.9 0.4 1.7 4.8 1.4 3.0 0.2 1.5 0.6 1.3 0.9 3.2 0.6 1.6 2.1 0.3 0.8 4.1 0.0 0.2 4.6 0.7 0.1 2.2 1.0 0.2 0.0 6.4 1.0 42.0 2.6 0.0 3.1 0.0 0.2 1.6 3.2 1.0 0.1 0.4 0.2 0.2 0.0 0.0 4.4 0.3 0.0 0.0 0.0 1.0 0.5 0.0 1.0 0.0 0.1 1.1 0.0 0.0 0.1 0.1 0.4 2.1 0.7 0.1 0.8 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.3 0.1 0.3 0.0 0.1 0.2 0.0 1.9 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.3 2.3 0.0 0.2 0.0 0.4 5.6 0.1 0.0 0.2 0.9 0.2 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 3.2 6.3 10.2 4.9 4.8 1.4 1.3 0.9 0.8 0.0 2.6 1.0 0.0 0.0 0.5 0.3 0.1 0.3 1.7 0.1 2.8 1.0 0.6 0.9 1.5 0.0 1.5 1.8 0.0 0.0 0.9 0.1 0.0 0.7 291.1 1.2 1.3 0.3 0.0 0.0 7.0 0.0 0.0 1.1 0.0 0.8 0.0 0.3 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.0 0.0 87.9 1.2 0.1 0.0 1.0 0.0 0.5 1.0 0.5 0.9 0.6 0.0 0.4 0.1 0.7 0.0 0.0 2.4 0.0 0.0 0.1 0.3 2.5 1.8 0.2 0.3 0.8 0.9 0.0 0.0 0.6 TRIM29 "ATDC, FLJ36085" ENSG00000137699 "Tripartite motif containing 29" Q14134 11 120111286-120185529 "Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 600.1;skin 1: 551.2;vagina: 269.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 272.0;Basal squamous epithelial cells: 250.4;Late spermatids: 150.3;Squamous epithelial cells: 552.9;Suprabasal keratinocytes: 460.6;Urothelial cells: 159.3" "Cancer enhanced" "Detected in many" "head and neck cancer: 93.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 399.9;HBEC3-KT: 107.5;hTCEpi: 476.0;RT4: 190.5;SiHa: 268.3" "Not detected" "Not detected" "Region enriched" "Detected in single" 9 "spinal cord: 4.0" "HPA020053, HPA074841" Enhanced Approved "Nucleoplasm,Intermediate filaments,Cytosol" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments" "Nucleoplasm, Cytosol" "HPA020053: AB_1858280, HPA074841: " "unprognostic (1.10e-1)" "unprognostic (6.22e-2)" "unprognostic (1.53e-1)" "prognostic unfavorable (2.88e-4)" "unprognostic (9.79e-3)" "unprognostic (3.08e-2)" "unprognostic (3.30e-1)" "unprognostic (5.24e-3)" "unprognostic (1.37e-1)" "unprognostic (1.16e-1)" "prognostic unfavorable (4.46e-4)" "unprognostic (9.37e-2)" "unprognostic (4.29e-3)" "prognostic favorable (4.93e-4)" "unprognostic (2.59e-1)" "unprognostic (2.91e-2)" "unprognostic (4.15e-2)" 2.5 1.0 0.1 0.4 0.2 0.4 41.7 0.0 0.4 133.8 1.6 3.0 1.7 2.6 4.8 600.1 17.4 3.5 0.4 0.3 0.0 1.7 1.8 3.7 0.0 1.8 0.6 0.4 1.0 0.0 8.1 30.7 1.8 31.4 2.6 0.3 131.5 23.7 2.2 551.2 1.0 1.5 2.6 0.3 1.4 2.7 0.0 19.9 0.4 0.2 107.2 55.8 269.1 0.6 34.4 2.5 0.0 0.0 0.0 0.0 0.9 0.1 0.8 0.2 0.1 0.8 25.6 0.2 3.9 0.2 0.5 399.9 0.0 107.5 0.0 0.1 0.0 0.2 25.4 0.4 0.0 0.2 0.5 0.0 476.0 0.0 2.6 0.0 0.0 0.0 0.2 0.7 0.0 4.4 0.0 0.0 0.1 11.4 0.1 0.0 0.3 0.0 0.3 190.5 1.3 5.9 268.3 35.2 0.1 0.2 1.9 0.0 0.4 0.1 2.1 0.2 0.1 0.2 0.3 0.2 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.4 0.3 0.0 1.8 0.6 1.8 2.6 0.0 0.6 0.5 0.0 1.5 3.3 0.2 272.0 106.1 76.4 250.4 0.0 9.5 58.8 1.2 1.5 39.2 0.0 0.0 41.0 0.2 11.3 0.0 5.0 28.1 8.7 0.8 3.4 2.4 0.0 0.5 4.3 7.1 5.6 1.1 3.6 1.3 0.0 0.0 0.4 5.0 0.0 0.1 2.1 12.2 0.0 30.3 150.3 0.6 1.4 23.2 1.0 0.0 0.0 0.0 0.0 0.1 57.1 11.3 0.0 0.0 66.0 0.2 0.6 64.6 0.0 0.0 0.1 4.9 0.8 2.6 552.9 460.6 24.8 2.4 0.1 3.7 159.3 TRIM39 RNF23 ENSG00000204599 "Tripartite motif containing 39" Q9HCM9 6 30326479-30343729 "Enzymes, Predicted intracellular proteins" "Apoptosis, Cell cycle, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051120, HPA059496" Uncertain Supported Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 2: Karpas-707 - Immune response" "Cluster 7: Non-specific - Mitochondria" Cytosol "HPA051120: AB_2681348, HPA059496: AB_2684040" "unprognostic (2.90e-1)" "unprognostic (1.61e-2)" "unprognostic (2.79e-2)" "unprognostic (2.86e-2)" "unprognostic (6.38e-2)" "unprognostic (4.55e-2)" "unprognostic (1.46e-2)" "unprognostic (1.15e-2)" "unprognostic (3.47e-1)" "unprognostic (9.44e-2)" "prognostic favorable (2.50e-4)" "unprognostic (1.30e-2)" "unprognostic (4.69e-2)" "unprognostic (6.35e-3)" "unprognostic (1.46e-1)" "unprognostic (1.06e-1)" "unprognostic (2.39e-3)" 10.0 8.7 0.8 1.7 1.0 3.1 10.2 1.3 1.1 11.4 1.5 13.6 1.6 12.1 2.2 13.1 11.7 1.3 8.7 0.9 0.9 9.8 11.6 9.7 1.6 1.3 1.0 11.5 12.2 2.1 14.8 1.6 1.0 10.8 1.5 1.5 10.2 2.0 14.3 9.3 11.9 1.8 0.8 14.3 11.0 20.7 1.1 1.7 11.6 1.4 2.1 12.9 9.5 1.1 3.2 0.1 2.6 4.8 1.2 1.2 2.7 1.4 1.8 2.1 1.9 3.8 0.4 4.1 2.8 2.7 1.3 1.0 3.1 2.2 2.2 3.2 3.4 3.2 0.5 1.4 2.7 4.8 3.5 1.4 1.8 2.7 2.9 3.2 1.3 3.4 4.9 3.2 2.7 2.9 1.0 1.0 3.6 1.3 2.2 2.2 0.5 3.1 2.2 3.0 5.7 2.8 1.1 2.3 2.8 2.5 3.1 1.2 1.2 2.3 1.8 2.8 4.9 5.7 7.6 4.2 1.3 1.7 3.6 1.0 0.9 4.1 2.7 1.3 2.4 1.8 1.9 2.0 0.9 1.6 2.2 2.2 4.5 2.6 1.4 0.7 1.7 1.4 0.8 1.0 1.3 1.1 0.9 0.9 1.3 1.0 1.0 0.8 1.1 1.1 5.9 3.2 7.2 0.7 14.2 3.7 5.6 2.6 6.8 6.0 7.5 5.2 5.6 2.8 3.5 1.8 6.2 4.7 11.9 5.5 7.9 4.6 4.6 11.2 4.1 4.8 5.4 3.6 0.9 6.1 5.7 4.1 15.3 13.1 5.7 4.2 5.7 3.7 3.3 3.3 1.1 7.3 4.1 7.2 5.0 7.8 2.8 7.3 3.6 1.0 4.3 6.9 8.2 0.5 0.9 6.8 10.0 4.5 10.9 3.7 7.5 4.0 7.2 7.6 0.0 3.8 5.8 19.1 10.0 5.3 4.1 10.0 15.3 3.5 4.4 5.3 TRIM42 "FLJ40097, PPP1R40, T4A1" ENSG00000155890 "Tripartite motif containing 42" Q8IWZ5 3 140678064-140701150 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 41 "testis: 16.7" "Group enriched" "Detected in some" 118 "Early spermatids: 245.8;Late spermatids: 157.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA003581, HPA022481" Uncertain Nucleoplasm,Mitochondria NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Mitochondria" "HPA003581: AB_1080383, HPA022481: AB_1858301" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 245.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 157.9 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TRIM60 "FLJ35882, RNF129, RNF33" ENSG00000176979 "Tripartite motif containing 60" Q495X7 4 165016458-165041749 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "placenta: 1.5;testis: 1.5" "Group enriched" "Detected in some" 4 "Cytotrophoblasts: 5.1;Early spermatids: 3.0;Extravillous trophoblasts: 10.6;Spermatocytes: 9.6;Spermatogonia: 8.2;Syncytiotrophoblasts: 5.6" "Cancer enriched" "Detected in single" 103 "testis cancer: 5.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "BEWO: 14.2" "Not detected" "Not detected" "HPA035809, HPA035810, HPA061496" Uncertain Uncertain Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoli "Nucleoplasm, Cytosol" "HPA035809: AB_2674794, HPA035810: AB_10601827, HPA061496: AB_2684540" "unprognostic (1.10e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 14.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.3 0.2 0.3 0.2 0.3 0.0 0.4 0.5 0.9 0.7 0.0 0.1 0.0 0.0 5.1 0.6 0.0 0.0 0.0 3.0 0.8 0.9 0.7 0.0 0.0 0.2 0.0 10.6 0.3 0.0 1.5 0.0 0.2 0.0 1.1 0.5 0.0 0.3 0.0 0.0 1.3 0.0 0.5 0.9 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.4 0.7 0.3 0.0 0.1 0.8 0.5 0.0 0.0 0.3 9.6 8.2 0.0 0.3 5.6 0.7 0.2 0.0 0.1 TRIM71 "LIN-41, LIN41" ENSG00000206557 "Tripartite motif containing 71" Q2Q1W2 3 32817997-32897824 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "RNA-mediated gene silencing, Ubl conjugation pathway" "Developmental protein, RNA-binding, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 4.8" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 9.6;Extravillous trophoblasts: 15.6;Inhibitory neurons: 4.5;Oligodendrocyte precursor cells: 4.5;Spermatogonia: 13.7" "Cancer enriched" "Detected in some" 28 "testis cancer: 28.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 31.4;BEWO: 94.5;Hep G2: 63.8;NTERA-2: 84.3;SuSa: 76.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA038141, HPA038142" Uncertain Approved "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 5: NTERA-2 - Transcription" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane, Actin filaments, Focal adhesion sites" "HPA038141: AB_2675857, HPA038142: AB_10697240" "unprognostic (2.93e-2)" "unprognostic (4.29e-3)" "unprognostic (1.70e-1)" "unprognostic (1.02e-2)" "unprognostic (2.58e-2)" "unprognostic (3.27e-2)" "unprognostic (2.09e-2)" "unprognostic (1.25e-1)" "unprognostic (3.16e-2)" "unprognostic (3.04e-1)" "unprognostic (1.11e-2)" "unprognostic (3.11e-1)" "unprognostic (4.36e-6)" "unprognostic (3.92e-2)" "unprognostic (9.27e-2)" "unprognostic (8.17e-2)" "unprognostic (4.65e-2)" 0.0 0.0 1.0 0.0 1.0 0.2 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.8 0.9 0.0 0.7 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 31.4 0.0 0.0 0.0 94.5 0.0 0.0 0.0 0.0 23.1 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 1.6 0.0 63.8 0.0 1.8 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.3 0.4 0.0 0.0 0.6 6.9 84.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 76.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.0 0.0 0.8 0.9 0.8 0.1 0.1 0.1 0.0 0.8 0.2 0.0 9.6 4.1 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.1 0.0 2.7 0.0 1.8 0.0 0.0 3.9 0.0 0.0 0.0 0.0 1.0 0.2 0.0 0.2 0.0 0.0 3.1 0.0 15.6 0.3 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.0 4.5 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 1.0 0.1 0.0 0.0 4.5 0.1 0.0 0.0 0.4 0.0 0.0 0.0 3.6 0.7 0.5 0.0 0.0 0.1 0.3 13.7 0.0 0.0 4.0 0.1 0.0 0.0 0.0 TRMT13 "CCDC76, FLJ10287, FLJ11219" ENSG00000122435 "TRNA methyltransferase 13 homolog" Q9NUP7 1 100133150-100150498 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 97.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA028494 Approved Approved "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Plasma membrane" "Nuclear bodies, Cytosol" "HPA028494: AB_10601254" "unprognostic (1.12e-1)" "unprognostic (3.33e-1)" "unprognostic (5.76e-2)" "unprognostic (2.37e-1)" "unprognostic (9.17e-3)" "unprognostic (4.97e-2)" "prognostic unfavorable (5.81e-5)" "unprognostic (1.16e-3)" "unprognostic (3.28e-2)" "unprognostic (8.08e-2)" "unprognostic (3.22e-1)" "unprognostic (1.02e-3)" "prognostic unfavorable (6.89e-6)" "unprognostic (3.12e-2)" "unprognostic (7.71e-2)" "unprognostic (1.99e-2)" "unprognostic (1.70e-3)" 8.8 8.7 6.9 12.2 9.8 5.2 14.5 9.6 9.6 11.2 6.7 9.3 11.2 13.9 11.8 8.5 9.2 7.2 8.0 6.5 9.7 8.8 8.7 7.8 18.2 8.5 9.0 13.5 11.5 12.9 6.8 10.7 8.7 10.4 11.3 21.7 9.1 8.1 13.1 14.7 10.7 10.1 7.0 14.1 10.0 9.4 8.5 11.3 12.0 6.2 14.6 9.5 10.3 14.9 17.5 10.0 16.5 11.5 8.7 16.9 18.0 18.0 7.1 13.4 11.1 11.9 7.0 28.7 21.8 14.4 8.9 15.4 30.6 14.0 23.1 29.0 24.2 17.2 23.1 11.6 15.7 30.0 15.4 11.9 15.5 25.5 33.3 8.4 12.4 21.0 36.6 17.9 13.6 6.7 24.6 15.6 23.0 16.7 19.9 26.0 25.0 15.7 11.1 13.6 10.7 17.9 16.6 15.8 21.6 16.1 9.3 26.1 13.0 17.8 11.9 15.1 24.3 22.8 20.0 34.0 20.1 23.5 7.0 0.2 5.8 3.1 10.5 6.1 13.0 19.9 11.3 10.6 7.0 18.7 16.8 14.0 2.5 7.9 5.1 12.8 8.6 5.6 6.9 9.8 9.6 9.6 6.5 9.7 8.5 9.0 8.7 7.0 8.5 14.9 13.1 25.6 17.0 34.0 29.0 9.7 14.2 14.2 19.9 38.9 10.7 7.9 11.1 12.8 22.2 14.7 29.2 14.2 18.9 8.0 13.7 10.5 20.9 14.3 21.0 15.7 20.4 11.3 23.1 6.1 10.2 13.7 11.7 8.0 21.5 18.7 17.9 11.4 7.6 28.6 32.1 9.9 18.3 10.1 7.0 6.0 24.8 10.3 10.6 25.3 14.7 16.6 41.2 33.7 97.4 8.5 9.6 18.4 9.0 12.6 13.0 10.7 20.4 44.7 19.7 16.0 13.4 47.6 21.9 12.2 11.9 7.3 21.5 15.8 13.6 10.0 TRPM3 "GON-2, KIAA1616, LTRPC3" ENSG00000083067 "Transient receptor potential cation channel subfamily M member 3" Q9HCF6 9 70529060-71446904 "Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "choroid plexus: 801.0" "Cell type enhanced" "Detected in many" "Astrocytes: 905.0;Excitatory neurons: 390.3;Inhibitory neurons: 186.9;Muller glia cells: 184.5" "Cancer enhanced" "Detected in single" "renal cancer: 0.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "HAP1: 17.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA072650, HPA074393" Enhanced Approved Vesicles NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA072650: , HPA074393: " "unprognostic (3.74e-1)" "unprognostic (6.30e-2)" "unprognostic (4.79e-2)" "unprognostic (4.81e-2)" "unprognostic (1.38e-2)" "unprognostic (8.88e-2)" "unprognostic (1.49e-2)" "unprognostic (2.19e-2)" "unprognostic (1.11e-1)" "unprognostic (1.89e-2)" "unprognostic (6.10e-2)" "unprognostic (1.15e-2)" "unprognostic (1.82e-7)" "unprognostic (3.51e-2)" "unprognostic (5.64e-2)" "unprognostic (1.74e-2)" "unprognostic (1.50e-2)" 0.7 0.6 22.0 0.1 30.4 0.2 0.1 40.5 9.6 1.0 801.0 0.2 0.8 1.1 1.3 0.1 0.4 0.4 0.8 39.3 27.8 16.5 0.2 0.1 0.1 36.7 46.8 3.6 0.5 0.0 2.9 0.1 20.8 0.5 0.1 23.0 0.1 2.5 0.3 0.1 0.0 0.2 25.2 0.3 0.6 5.1 41.6 0.2 0.9 0.1 0.0 0.1 0.4 15.4 0.0 0.0 0.9 0.0 1.1 2.6 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 17.2 0.0 0.1 0.0 0.1 0.1 1.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 2.3 0.2 0.0 0.0 1.0 4.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.2 0.0 0.9 0.0 1.1 0.0 0.2 0.0 0.3 0.2 0.0 0.0 3.1 0.0 0.1 3.1 0.0 0.0 0.0 0.0 0.4 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 22.0 30.4 40.5 9.6 39.3 27.8 36.7 46.8 20.8 25.2 41.6 15.4 0.3 3.2 3.0 905.0 0.5 0.4 0.9 0.0 0.6 16.4 0.3 0.5 5.3 5.7 2.5 16.5 66.7 0.1 0.2 0.1 5.9 0.1 4.8 1.4 1.0 1.3 15.4 0.0 390.3 0.2 0.1 3.0 0.0 3.2 0.0 1.4 0.7 0.3 0.2 1.7 186.9 0.1 0.0 0.9 1.4 2.3 5.6 0.8 0.0 56.2 0.2 184.5 1.0 105.6 8.3 0.1 0.1 9.1 0.0 0.5 0.1 33.3 0.8 10.1 0.0 3.5 1.3 1.3 0.6 0.0 0.9 0.3 0.9 0.6 0.0 0.3 TRPV6 "CaT1, ECAC2" ENSG00000165125 "Transient receptor potential cation channel subfamily V member 6" Q9H1D0 7 142871208-142885745 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Calmodulin-binding, Ion channel" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 38.3;prostate: 23.5;salivary gland: 69.3" "Cell type enhanced" "Detected in many" "Cholangiocytes: 18.6;Collecting duct cells: 27.6;Cytotrophoblasts: 17.0;Ductal cells: 80.1;Early spermatids: 25.9;Late spermatids: 37.3" "Cancer enriched" "Detected in many" 5 "prostate cancer: 16.1" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 9.6;HaCaT: 18.0;RT4: 30.7;SK-BR-3: 23.5;T-47d: 52.8" "Low region specificity" "Detected in single" HPA062864 Approved NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 6: T47d - Mammary gland" "Cluster 1: Pancreatic cells - Digestion" "HPA062864: AB_2684885" "unprognostic (9.85e-2)" "unprognostic (1.60e-2)" "unprognostic (6.29e-2)" "unprognostic (8.72e-2)" "unprognostic (1.08e-1)" "unprognostic (1.14e-1)" "unprognostic (7.11e-2)" "unprognostic (5.43e-2)" "unprognostic (3.50e-1)" "unprognostic (4.56e-2)" "unprognostic (3.89e-2)" "unprognostic (3.27e-2)" "unprognostic (8.49e-2)" "unprognostic (9.39e-3)" "unprognostic (1.69e-1)" "unprognostic (7.17e-3)" "unprognostic (3.53e-2)" 0.0 0.0 0.5 0.0 0.6 0.1 4.2 0.6 1.1 0.5 0.6 0.1 8.1 0.1 0.3 2.7 0.2 8.2 0.1 0.5 0.6 5.2 0.9 0.2 0.0 0.6 0.6 0.0 38.3 1.5 0.5 11.9 0.8 23.5 0.0 0.0 69.3 1.6 0.0 6.4 2.2 0.0 0.6 0.0 4.5 1.2 0.6 0.0 1.8 0.0 0.2 0.4 1.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 9.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.7 1.9 0.1 0.0 23.5 0.6 0.9 52.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.6 1.1 0.5 0.6 0.6 0.6 0.8 0.6 0.6 0.6 0.0 3.2 0.0 0.0 0.0 0.5 1.1 0.2 5.2 0.6 2.4 2.0 1.9 18.6 1.4 27.6 0.0 17.0 0.1 0.1 0.0 80.1 25.9 0.7 0.2 0.2 0.0 0.0 0.1 3.3 0.8 0.2 3.6 1.6 0.0 0.0 0.4 0.0 1.6 3.3 0.1 0.3 0.0 0.0 0.0 37.3 0.9 0.2 0.0 0.0 2.0 0.7 0.0 0.0 6.8 8.9 0.1 0.0 0.0 10.6 0.1 0.3 0.7 0.2 0.0 1.0 0.3 0.3 0.4 4.3 1.8 6.0 0.0 0.0 0.2 3.1 TRUB2 CLONE24922 ENSG00000167112 "TruB pseudouridine synthase family member 2" O95900 9 128305159-128322447 "Predicted intracellular proteins" "mRNA processing" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021211 Uncertain NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "HPA021211: AB_1858375" "unprognostic (2.40e-1)" "unprognostic (2.02e-2)" "unprognostic (1.31e-1)" "unprognostic (3.72e-2)" "unprognostic (7.38e-2)" "unprognostic (2.47e-1)" "unprognostic (1.13e-1)" "unprognostic (4.52e-2)" "unprognostic (1.22e-1)" "unprognostic (7.49e-2)" "unprognostic (3.04e-2)" "unprognostic (4.81e-3)" "prognostic favorable (5.57e-10)" "unprognostic (8.74e-3)" "unprognostic (8.81e-2)" "unprognostic (1.75e-1)" "unprognostic (1.08e-1)" 3.7 8.5 8.7 3.6 9.0 4.2 4.7 8.9 9.3 3.3 8.7 4.5 5.0 3.3 2.9 6.3 4.1 2.7 8.7 8.5 8.1 6.5 12.9 2.4 4.5 9.3 9.3 3.8 5.2 7.2 6.8 2.7 9.8 3.6 4.2 3.6 4.8 3.4 7.2 5.4 4.3 3.2 7.7 3.6 4.6 3.1 9.5 3.5 4.7 9.8 4.3 4.0 3.5 9.9 6.6 14.9 6.7 9.2 10.7 7.9 7.1 7.1 8.5 11.6 9.5 11.1 8.3 14.7 6.0 9.7 11.0 17.5 15.4 12.4 7.8 7.1 10.2 6.9 12.8 10.4 8.2 12.7 8.9 10.0 13.7 11.4 10.7 7.2 12.0 12.8 26.2 6.4 9.3 19.7 17.1 14.7 9.2 22.2 19.0 13.3 10.9 21.0 10.7 5.9 14.4 10.6 13.2 14.6 9.5 5.2 19.1 8.7 8.1 9.4 7.5 11.2 8.6 7.5 16.4 11.9 9.9 9.9 10.5 3.6 3.6 1.1 5.0 3.8 5.7 6.3 4.8 5.7 5.5 5.3 5.5 5.7 1.8 6.5 2.0 3.8 6.2 3.8 8.7 9.0 8.9 9.3 8.5 8.1 9.3 9.3 9.8 7.7 9.5 9.9 10.9 25.6 10.3 1.6 17.1 9.6 13.7 43.0 15.4 21.3 14.6 15.7 49.9 24.3 27.0 35.0 16.7 51.6 10.9 19.8 64.6 39.0 12.9 15.1 20.7 16.4 19.1 16.2 5.0 35.4 45.9 15.4 27.0 15.9 8.2 22.0 17.2 50.7 31.0 3.3 5.2 26.4 34.6 9.0 4.1 16.4 20.8 12.4 12.4 3.7 16.8 15.4 18.6 3.0 10.5 27.2 19.1 18.0 17.8 14.9 34.0 78.6 16.9 16.7 0.0 17.2 16.3 15.8 19.2 22.1 10.5 28.0 13.9 46.1 35.3 11.1 TSC22D4 "THG-1, TILZ2" ENSG00000166925 "TSC22 domain family member 4" Q9Y3Q8 7 100463359-100479232 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "brain: 601.0;choroid plexus: 224.0" "Cell type enriched" "Detected in all" 4 "Muller glia cells: 778.8" "Cancer enhanced" "Detected in all" "glioma: 118.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "NB-4: 198.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006757 Uncertain Approved Cytosol NA NA 160000 "Cluster 52: Eosinophils - Transcription" "Cluster 70: Brain - Nervous system development" "Cluster 24: NB-4 - Immune response" "Cluster 5: Muller glia cells - Visual perception" Cytosol "HPA006757: AB_1080403" "unprognostic (2.34e-2)" "unprognostic (3.06e-2)" "prognostic unfavorable (2.66e-4)" "unprognostic (5.77e-2)" "unprognostic (1.69e-1)" "unprognostic (3.06e-1)" "prognostic unfavorable (9.45e-4)" "unprognostic (9.96e-2)" "unprognostic (1.27e-1)" "unprognostic (1.62e-2)" "unprognostic (2.31e-2)" "unprognostic (3.36e-1)" "unprognostic (1.09e-1)" "unprognostic (1.54e-2)" "unprognostic (3.84e-2)" "unprognostic (7.36e-2)" "unprognostic (3.81e-3)" 37.1 52.7 437.1 33.6 601.0 72.0 36.1 524.6 456.9 43.4 224.0 47.5 23.5 40.5 10.1 73.0 36.8 14.4 59.7 384.9 457.3 64.1 30.0 42.6 40.6 527.5 563.9 44.1 37.3 18.5 52.1 22.7 484.3 55.7 10.7 21.9 97.6 22.2 26.2 58.8 44.4 14.0 485.2 95.2 38.6 36.7 538.9 31.2 34.5 28.7 23.2 37.8 46.8 565.4 42.0 30.8 10.3 33.7 34.2 40.5 19.9 30.5 49.6 28.3 25.8 16.9 25.0 36.8 36.1 24.4 66.0 31.2 12.2 26.7 9.9 65.6 25.2 34.2 34.5 14.6 54.4 44.1 86.3 45.7 24.0 32.4 32.2 33.0 58.3 29.0 75.2 64.2 22.9 74.3 55.6 198.4 14.0 35.7 42.6 89.7 8.1 51.6 23.2 22.3 8.8 25.1 41.4 78.8 65.5 16.7 22.5 63.1 50.2 38.4 39.1 95.0 22.8 40.9 42.6 27.1 35.7 66.4 47.8 9.7 18.7 30.0 19.0 20.2 14.9 11.9 16.3 17.9 12.7 11.8 15.2 16.2 56.1 18.8 20.5 13.3 25.0 18.2 437.1 601.0 524.6 456.9 384.9 457.3 527.5 563.9 484.3 485.2 538.9 565.4 16.7 12.8 8.9 123.4 50.8 32.8 35.9 50.7 37.5 15.4 47.3 61.3 17.7 44.3 32.5 40.5 6.2 30.7 69.3 60.3 137.0 63.5 1.7 14.0 25.5 26.1 33.6 60.6 3.8 33.9 35.3 29.8 21.4 19.9 15.9 36.1 42.1 11.1 79.9 18.5 4.6 32.1 38.7 57.7 67.1 5.2 45.7 56.7 55.2 14.0 77.2 778.8 116.4 50.8 162.6 60.6 52.7 39.9 31.8 59.2 62.8 21.0 13.7 18.2 46.0 16.1 34.5 1.7 5.4 32.8 33.8 79.1 78.2 28.9 31.7 80.3 TSGA10 "CEP4L, CT79" ENSG00000135951 "Testis specific 10" Q9BZW7 2 98997261-99154964 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "testis: 51.5" "Cell type enhanced" "Detected in all" "Early spermatids: 458.9;Late spermatids: 294.2;Oligodendrocytes: 144.9;Spermatocytes: 206.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "RPTEC TERT1: 4.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036879 Approved Cytosol NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "HPA036879: AB_10671715" "unprognostic (1.71e-3)" "unprognostic (6.68e-2)" "unprognostic (2.97e-1)" "unprognostic (1.12e-1)" "unprognostic (4.95e-2)" "unprognostic (3.69e-2)" "unprognostic (1.04e-2)" "unprognostic (2.52e-2)" "unprognostic (1.98e-2)" "unprognostic (2.39e-1)" "unprognostic (1.15e-5)" "unprognostic (2.32e-1)" "unprognostic (2.82e-6)" "unprognostic (1.06e-2)" "unprognostic (9.91e-3)" "unprognostic (9.79e-2)" "unprognostic (8.37e-4)" 1.1 1.0 1.8 0.6 1.6 0.7 1.4 1.6 1.9 1.3 3.7 0.9 1.0 1.1 1.6 0.6 12.6 1.1 0.2 1.8 1.6 3.0 0.5 1.6 1.0 3.4 3.5 0.5 1.7 1.6 2.5 0.4 2.5 1.0 1.3 2.6 1.1 0.6 0.1 1.9 0.6 0.3 2.7 0.8 1.4 51.5 1.5 1.1 3.1 0.2 0.8 0.6 0.4 3.7 0.8 0.2 1.2 0.5 0.6 0.7 0.9 0.0 0.1 0.3 0.2 0.2 0.8 0.7 0.2 0.0 0.5 0.2 0.2 0.2 0.3 1.0 0.8 0.1 0.0 0.3 0.0 0.5 1.7 0.9 1.0 0.1 0.1 0.7 0.0 0.9 0.0 0.0 0.6 0.2 0.2 0.4 0.1 0.3 0.2 0.3 0.1 0.2 4.2 0.7 1.7 0.2 0.9 0.7 0.2 1.3 0.2 0.3 0.4 0.2 0.4 0.0 0.1 0.6 0.3 0.3 0.3 1.0 0.4 0.1 0.2 0.2 0.6 0.0 0.7 0.7 0.7 0.8 0.0 0.8 1.1 0.7 0.0 1.0 0.0 0.4 0.7 0.3 1.8 1.6 1.6 1.9 1.8 1.6 3.4 3.5 2.5 2.7 1.5 3.7 3.1 3.2 9.2 35.3 13.3 3.6 10.3 8.6 6.2 19.3 13.9 15.4 7.1 17.2 14.5 23.9 29.2 9.7 5.6 4.7 25.4 8.4 458.9 80.6 4.5 4.0 15.5 8.6 73.4 10.5 4.3 5.8 8.6 10.9 5.1 5.3 4.2 7.1 4.6 20.2 57.9 6.7 12.2 3.1 1.4 294.2 11.1 5.1 1.8 23.4 4.5 21.1 15.5 27.6 144.9 4.7 12.2 9.8 8.1 7.8 8.0 12.9 107.9 36.6 6.6 5.7 6.2 206.8 36.6 5.6 4.4 9.3 8.9 5.9 8.4 7.9 TSHZ1 "NY-CO-33, SDCCAG33, TSH1" ENSG00000179981 "Teashirt zinc finger homeobox 1" Q6ZSZ6 18 75210755-75289950 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 84.9;Peritubular cells: 187.3;Theca cells: 83.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 44.4" "Region enriched" "Detected in all" 5 "olfactory bulb: 115.6" "Low region specificity" "Detected in all" HPA006982 Approved Approved Nucleoplasm NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA006982: AB_1079886" "unprognostic (2.02e-1)" "unprognostic (2.61e-2)" "unprognostic (4.03e-1)" "unprognostic (5.89e-2)" "unprognostic (1.66e-1)" "unprognostic (1.23e-2)" "unprognostic (1.27e-1)" "unprognostic (1.24e-1)" "unprognostic (4.12e-2)" "unprognostic (9.05e-2)" "unprognostic (5.64e-2)" "unprognostic (1.69e-1)" "unprognostic (3.43e-3)" "unprognostic (1.26e-1)" "unprognostic (8.00e-2)" "prognostic unfavorable (1.71e-5)" "unprognostic (3.42e-3)" 12.0 7.7 16.3 7.1 14.1 3.3 12.1 23.5 21.0 17.4 6.3 18.1 13.8 11.4 9.3 10.0 15.9 10.4 10.9 17.0 10.4 12.1 8.2 8.0 7.3 18.8 11.5 35.4 7.2 9.2 9.7 29.7 19.3 8.9 9.3 7.9 12.5 11.1 9.2 10.6 13.7 9.3 20.1 9.4 8.8 6.3 15.5 12.3 8.2 6.4 5.3 10.9 11.0 14.1 5.4 7.0 2.2 12.8 18.8 8.9 2.2 24.2 22.6 4.0 7.4 3.2 12.9 10.8 3.0 21.9 4.5 4.8 2.9 6.9 1.4 44.4 23.2 8.3 14.5 4.3 4.9 20.0 9.4 9.1 7.2 3.3 6.5 6.2 10.1 12.5 4.7 19.1 6.6 5.2 14.3 11.4 0.9 6.3 7.6 12.9 6.6 12.9 7.6 3.9 15.9 12.1 6.8 8.8 6.8 0.8 2.0 10.4 7.6 8.7 5.9 6.0 3.9 6.2 15.9 8.7 8.6 16.6 8.1 0.0 0.5 0.5 2.1 0.2 1.4 0.4 1.0 1.8 0.8 0.6 1.5 2.2 0.3 1.5 0.2 0.8 0.4 0.7 16.3 14.1 23.5 21.0 17.0 10.4 18.8 11.5 19.3 20.1 15.5 14.1 60.2 12.8 14.0 34.3 7.1 17.0 5.6 4.8 27.9 40.8 12.2 12.6 24.4 25.8 7.9 3.7 2.1 4.6 25.6 25.4 3.9 7.5 1.2 12.5 33.9 34.4 16.9 6.9 24.9 10.0 2.2 28.8 4.6 18.2 7.0 22.5 21.0 20.5 6.4 11.8 27.7 15.0 10.2 10.8 30.9 5.9 64.7 14.3 8.8 30.0 11.2 17.9 24.7 84.9 21.3 2.9 14.7 187.3 10.6 7.3 29.7 18.4 9.1 12.1 26.3 21.3 12.2 1.4 4.8 33.1 13.2 3.6 18.2 83.2 17.9 5.4 TSPAN1 "NET-1, TSPAN-1" ENSG00000117472 "Tetraspanin 1" O60635 1 46175073-46185962 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 593.8;kidney: 244.3" "Cell type enhanced" "Detected in many" "Club cells: 723.5;Distal enterocytes: 1983.8;Late spermatids: 838.1;Paneth cells: 1127.7;Respiratory ciliated cells: 1817.6" "Cancer enhanced" "Detected in all" "prostate cancer: 455.6" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 57 "plasmacytoid DC: 5.6" "Lineage enriched" "Detected in single" 57 "dendritic cells: 5.6" "Cell line enhanced" "Detected in many" "A-431: 129.6;CAPAN-2: 216.7;HaCaT: 151.4;hTCEpi: 173.6;OE19: 257.9;RPTEC TERT1: 628.4;RT4: 308.2" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA011909 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Vesicles" "HPA011909: AB_2668565" "unprognostic (1.21e-1)" "unprognostic (3.11e-1)" "unprognostic (3.67e-2)" "unprognostic (4.12e-1)" "unprognostic (2.69e-2)" "unprognostic (1.35e-1)" "unprognostic (4.41e-2)" "unprognostic (4.68e-2)" "unprognostic (2.52e-2)" "unprognostic (1.44e-1)" "unprognostic (1.88e-3)" "unprognostic (8.73e-2)" "prognostic favorable (9.28e-6)" "unprognostic (5.90e-2)" "unprognostic (2.61e-1)" "unprognostic (4.90e-2)" "unprognostic (4.30e-2)" 1.9 4.3 0.5 53.2 0.7 0.0 6.2 1.7 1.1 78.2 1.4 523.3 25.4 17.7 34.7 5.5 122.4 28.9 0.9 0.5 0.5 244.3 3.9 32.1 0.4 1.2 0.6 0.4 3.1 72.0 17.3 1.1 1.1 194.7 593.8 0.0 101.0 65.9 0.8 2.5 96.7 20.8 1.0 0.7 213.1 27.3 0.6 1.9 121.9 0.1 4.9 104.9 9.9 1.8 129.6 2.0 0.0 0.0 0.2 0.0 1.8 0.1 2.7 0.1 0.0 0.0 216.7 0.0 40.2 0.3 0.2 151.4 0.0 111.2 0.1 0.0 0.0 0.0 1.1 7.6 0.0 0.0 0.2 0.0 173.6 0.7 60.9 3.6 0.3 1.3 0.0 0.0 1.6 4.9 0.0 0.5 0.1 257.9 8.1 0.1 0.1 1.6 628.4 308.2 1.9 0.0 0.3 13.0 0.5 0.5 9.0 0.1 1.4 0.0 0.7 0.4 0.7 1.5 0.1 0.1 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.5 0.7 1.7 1.1 0.5 0.5 1.2 0.6 1.1 1.0 0.6 1.8 2.5 25.6 29.5 0.3 7.4 1.0 194.4 499.9 4.0 0.0 14.5 11.0 0.7 11.5 723.5 579.4 0.0 0.3 0.2 1983.8 46.9 61.3 141.3 268.3 14.1 4.5 201.8 0.0 1.2 525.1 0.1 6.0 223.3 144.3 11.4 0.0 1.4 3.6 0.3 0.0 1.3 648.1 242.1 0.3 0.3 838.1 5.0 5.3 5.4 1.0 1.6 0.0 0.0 0.5 1.6 484.4 1127.7 1.9 0.7 211.7 505.4 477.8 1817.6 0.0 0.0 0.4 54.1 4.7 2.6 2.9 1.3 0.0 7.4 0.0 275.9 517.0 TSPAN6 "T245, TM4SF6, TSPAN-6" ENSG00000000003 "Tetraspanin 6" O43657 X 100627108-100639991 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 422.5;Granulosa cells: 684.8;Late spermatids: 1708.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 2.1" "Lineage enriched" "Detected in single" 6 "T-cells: 2.1" "Cell line enhanced" "Detected in many" "NTERA-2: 121.7;RT4: 153.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004109 Approved Approved "Nucleoli fibrillar center,Cell Junctions,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 15: RT4 - Unknown function" "Cluster 40: Granulosa cells - Unknown function" "Cell Junctions, Cytosol" "Nucleoli fibrillar center" "HPA004109: AB_1080301" "unprognostic (7.71e-2)" "unprognostic (8.97e-2)" "unprognostic (3.56e-2)" "unprognostic (2.57e-1)" "unprognostic (2.71e-3)" "unprognostic (5.93e-2)" "unprognostic (1.04e-1)" "unprognostic (1.09e-2)" "unprognostic (1.19e-2)" "unprognostic (1.80e-3)" "unprognostic (2.04e-3)" "unprognostic (8.76e-2)" "unprognostic (3.83e-3)" "unprognostic (4.28e-2)" "unprognostic (1.14e-1)" "unprognostic (2.24e-1)" "unprognostic (9.54e-3)" 29.6 18.2 7.2 4.9 7.5 0.6 34.2 7.2 8.9 26.9 26.8 40.0 19.7 20.5 14.8 46.8 39.5 16.7 8.6 7.4 9.0 36.5 70.2 11.3 3.0 8.7 9.3 53.4 20.2 34.7 36.9 20.0 8.2 18.9 33.1 6.2 52.6 10.3 4.6 9.7 18.5 7.2 8.9 8.7 14.8 74.9 9.6 4.2 19.3 5.3 6.8 32.2 24.1 12.0 24.8 23.0 80.6 42.2 28.7 16.6 30.4 12.9 17.3 20.3 47.6 54.9 37.7 0.0 53.3 12.2 16.9 19.9 0.3 19.7 25.8 0.1 33.3 3.8 14.9 62.0 17.1 0.1 2.5 30.2 9.3 19.5 6.6 34.4 49.3 0.0 0.0 0.1 21.7 19.8 0.1 0.3 121.7 35.4 18.4 0.0 35.5 0.0 33.0 153.5 4.7 20.3 11.6 10.0 18.5 61.9 16.6 3.3 12.7 16.0 24.4 24.3 8.6 0.1 0.2 0.3 13.4 0.0 11.5 0.3 0.0 0.1 0.3 0.0 1.1 0.1 0.8 0.3 0.0 0.1 2.1 1.2 0.3 0.1 0.1 0.1 0.0 0.3 7.2 7.5 7.2 8.9 7.4 9.0 8.7 9.3 8.2 8.9 9.6 12.0 147.0 3.2 10.1 14.4 2.3 7.1 41.0 75.7 29.0 0.6 72.5 46.1 8.2 50.1 89.4 93.8 0.0 28.7 1.1 94.9 23.5 80.3 422.5 54.0 21.4 37.4 33.6 4.8 0.9 12.6 40.7 25.6 21.9 19.2 0.0 684.8 47.5 104.0 4.5 0.0 0.8 47.9 193.3 10.2 3.1 1708.3 32.9 3.1 10.6 1.0 1.0 48.2 0.0 9.5 0.4 18.7 55.5 35.7 0.3 33.0 43.5 43.8 193.9 1.9 19.7 17.1 43.1 20.9 32.4 23.3 5.4 13.5 2.5 49.4 94.3 89.7 TSPAN7 "A15, CD231, DXS1692E, MRX58, MXS1, TALLA-1, TM4SF2" ENSG00000156298 "Tetraspanin 7" P41732 X 38561542-38688920 "CD markers, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Host-virus interaction" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 542.1" "Cell type enhanced" "Detected in many" "Astrocytes: 274.9;Excitatory neurons: 215.6;Hepatic stellate cells: 407.3;Inhibitory neurons: 249.8;Oligodendrocyte precursor cells: 353.4" "Cancer enhanced" "Detected in all" "glioma: 71.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HDLM-2: 109.5;JURKAT: 380.9;MOLT-4: 239.7;SCLC-21H: 129.0;U-266/70: 163.2" "Low region specificity" "Detected in all" "HPA003140, CAB062566, CAB068245" Enhanced NA NA "Cluster 32: T-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB062566: AB_2665608, CAB068245: AB_2665609, HPA003140: AB_1078454" "unprognostic (1.12e-2)" "unprognostic (1.42e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (3.40e-4)" "unprognostic (5.06e-2)" "unprognostic (3.90e-3)" "unprognostic (3.88e-3)" "unprognostic (1.37e-2)" "unprognostic (1.14e-1)" "unprognostic (2.01e-2)" "prognostic favorable (1.70e-4)" "unprognostic (1.54e-1)" "prognostic favorable (5.48e-7)" "unprognostic (5.65e-3)" "unprognostic (9.53e-2)" "unprognostic (1.48e-1)" "unprognostic (1.03e-3)" 56.1 125.6 355.5 17.2 433.8 1.3 33.5 369.5 542.1 42.6 271.3 68.1 36.3 43.8 37.6 33.6 36.5 25.8 70.3 413.7 334.3 56.2 45.0 67.4 41.1 290.3 298.8 19.6 19.8 13.9 28.0 25.1 283.6 18.8 64.6 286.9 12.5 26.8 153.9 19.4 34.0 51.1 291.7 96.3 14.5 4.8 331.7 15.7 51.3 232.3 28.9 29.7 16.9 384.6 0.1 0.0 2.9 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 3.8 1.6 0.0 109.5 14.9 0.5 0.0 67.2 0.0 0.1 1.2 1.5 0.0 0.0 0.0 0.0 0.0 380.9 0.0 0.4 1.7 0.4 239.7 0.0 11.2 0.1 0.0 14.6 4.6 0.0 11.0 1.4 129.0 14.4 0.0 0.0 4.3 6.5 0.0 0.3 0.0 0.1 3.1 0.1 1.0 163.2 54.8 0.0 5.4 0.4 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 355.5 433.8 369.5 542.1 413.7 334.3 290.3 298.8 283.6 291.7 331.7 384.6 116.1 12.8 23.8 274.9 1.1 10.6 2.7 6.3 6.2 92.0 1.0 3.8 34.1 1.5 4.6 11.0 43.8 0.4 0.2 69.1 23.5 0.4 0.0 2.1 1.6 153.3 18.7 5.3 215.6 0.6 0.4 14.0 4.6 5.6 10.1 108.1 407.3 4.8 45.1 97.6 249.8 23.5 0.0 15.0 10.0 1.9 0.6 1.5 14.2 46.9 0.0 102.3 0.0 353.4 50.6 0.9 21.9 3.0 1.5 2.4 40.3 9.8 1.2 107.4 59.2 26.5 11.7 0.6 3.3 9.9 6.5 0.8 2.6 27.0 35.7 0.9 TSPYL2 "CDA1, CINAP, CTCL, DENTT, HRIHFB2216, SE20-4, TSPX" ENSG00000184205 "TSPY like 2" Q9H2G4 X 53082367-53088540 "Predicted intracellular proteins" "Cell cycle, Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 367.4" "Cell type enhanced" "Detected in all" "dendritic cells: 190.0;T-cells: 224.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-2197: 114.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044133 Approved NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 7: Non-specific - Mitochondria" "HPA044133: AB_10965838" "unprognostic (3.29e-2)" "unprognostic (2.68e-3)" "prognostic unfavorable (3.23e-4)" "unprognostic (3.87e-3)" "unprognostic (1.06e-1)" "unprognostic (9.58e-2)" "unprognostic (1.36e-1)" "unprognostic (5.99e-3)" "unprognostic (3.18e-2)" "unprognostic (1.59e-1)" "prognostic favorable (6.74e-8)" "unprognostic (1.29e-1)" "prognostic unfavorable (8.16e-7)" "unprognostic (6.50e-2)" "unprognostic (9.93e-2)" "unprognostic (2.31e-1)" "unprognostic (3.10e-2)" 73.3 148.7 92.9 23.8 100.7 67.3 65.8 92.1 110.7 137.9 39.1 112.4 9.2 121.1 59.2 31.2 125.4 31.2 94.9 93.1 121.0 48.0 39.7 75.4 33.7 69.0 83.5 367.4 70.0 22.6 311.8 10.7 82.7 131.8 11.4 35.3 42.7 55.6 99.3 48.4 77.8 30.0 58.5 85.5 86.7 163.1 118.9 20.2 87.2 26.8 22.3 120.4 81.8 85.5 4.3 13.8 14.0 57.7 10.5 12.7 19.9 29.9 31.6 19.3 18.7 20.4 9.5 32.2 5.5 15.9 14.7 12.5 11.6 11.8 17.5 8.1 25.1 8.1 60.9 26.7 30.9 13.3 9.9 24.8 21.3 26.2 44.2 11.6 14.0 11.1 6.4 29.1 10.7 19.4 18.9 15.8 21.1 6.4 25.5 14.8 17.5 23.8 3.4 23.7 17.0 10.3 23.6 8.6 16.3 63.9 13.0 4.0 20.4 8.8 14.7 114.4 5.7 31.2 20.9 29.6 14.8 21.6 18.5 4.8 0.1 2.2 7.4 0.7 9.3 6.0 10.6 6.0 0.2 7.7 14.1 10.4 1.2 7.4 1.3 15.2 8.4 5.8 92.9 100.7 92.1 110.7 93.1 121.0 69.0 83.5 82.7 58.5 118.9 85.5 45.4 9.6 43.5 17.3 98.0 40.8 80.8 20.3 63.7 100.1 48.8 60.7 33.3 10.0 30.3 18.4 45.9 5.0 190.0 9.2 1.9 8.8 11.1 28.1 47.0 38.9 72.7 5.2 43.4 6.0 15.8 64.3 40.2 61.2 64.6 36.7 27.8 5.8 6.2 30.3 65.0 18.7 14.2 11.4 79.0 11.9 39.1 51.7 44.4 9.4 5.1 53.0 11.3 13.6 9.4 5.1 12.0 51.9 141.4 44.9 4.2 1.4 19.1 34.3 59.2 76.4 75.4 59.7 94.2 17.7 36.4 16.4 224.7 29.6 12.0 31.0 TTC6 "C14orf25, NCRNA00291" ENSG00000139865 "Tetratricopeptide repeat domain 6" Q86TZ1 14 37595847-38041442 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 7.9;prostate: 17.5" "Cell type enhanced" "Detected in some" "Breast glandular cells: 13.8;Club cells: 11.1;Early spermatids: 39.1;Late spermatids: 18.1;Spermatocytes: 10.7" "Group enriched" "Detected in some" 7 "breast cancer: 2.2;prostate cancer: 3.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 8.4;MCF7: 12.2;RT4: 8.4;T-47d: 22.8" "Not detected" "Not detected" "Region enriched" "Detected in some" 7 "midbrain: 9.7" HPA069293 Approved Centrosome NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 6: T47d - Mammary gland" "Cluster 35: Glandular cells - Unknown function" Centrosome "HPA069293: AB_2686110" "unprognostic (7.92e-2)" "unprognostic (6.95e-2)" "unprognostic (9.22e-2)" "unprognostic (1.98e-1)" "unprognostic (7.06e-2)" "unprognostic (1.22e-2)" "unprognostic (1.68e-1)" "unprognostic (3.60e-4)" "unprognostic (6.75e-2)" "unprognostic (2.07e-2)" "unprognostic (4.08e-4)" "unprognostic (5.60e-2)" "unprognostic (8.91e-8)" "unprognostic (1.76e-1)" "unprognostic (2.58e-1)" "unprognostic (1.60e-1)" "unprognostic (6.07e-3)" 0.0 0.0 0.5 0.2 0.8 0.0 7.9 0.1 0.8 0.1 1.1 1.0 0.6 0.0 0.0 0.4 0.3 0.7 0.0 0.7 1.0 0.0 3.5 1.1 0.0 2.5 5.0 0.0 0.0 0.0 0.3 0.0 1.3 17.5 0.5 0.0 2.7 0.1 0.0 0.7 0.7 0.0 3.9 0.0 3.6 5.8 3.9 0.0 0.0 0.0 0.1 1.4 0.3 1.0 0.7 0.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.6 0.0 0.4 0.0 0.0 2.4 1.3 0.2 0.0 0.0 3.4 0.0 1.2 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.0 12.2 0.0 0.0 0.0 1.7 4.5 0.0 0.0 0.0 1.0 8.4 2.4 0.0 0.0 4.5 0.0 0.0 22.8 0.0 0.0 0.0 0.3 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.8 0.1 0.8 0.7 1.0 2.5 5.0 1.3 3.9 3.9 1.0 0.2 0.0 8.4 0.3 0.1 0.0 2.8 1.5 6.2 0.0 13.8 6.9 0.8 1.5 11.1 0.0 0.0 0.0 0.2 0.4 0.0 0.0 39.1 0.0 0.0 0.4 7.7 0.0 6.4 0.0 0.0 0.4 7.1 0.1 0.0 0.0 0.0 2.5 0.0 0.0 1.0 0.7 0.0 0.0 0.0 18.1 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.8 0.4 0.0 4.9 0.0 0.0 7.5 0.0 0.0 0.2 0.4 10.7 1.9 2.3 0.0 0.0 0.3 0.0 1.1 3.1 TTC8 "BBS8, RP51" ENSG00000165533 "Tetratricopeptide repeat domain 8" Q8TAM2 14 88824153-88881078 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Transport" "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Mental retardation, Obesity, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 66.8;Theca cells: 69.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 13.8" "Lineage enriched" "Detected in many" 6 "granulocytes: 13.8" "Cell line enhanced" "Detected in all" "SH-SY5Y: 118.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" "unprognostic (1.19e-2)" "unprognostic (1.08e-1)" "unprognostic (5.47e-2)" "prognostic favorable (1.69e-5)" "unprognostic (1.49e-1)" "unprognostic (7.10e-2)" "unprognostic (5.00e-3)" "unprognostic (1.54e-1)" "unprognostic (2.19e-1)" "prognostic favorable (7.77e-4)" "unprognostic (3.54e-2)" "unprognostic (2.51e-1)" "prognostic favorable (4.89e-4)" "unprognostic (1.65e-2)" "unprognostic (1.84e-1)" "unprognostic (2.44e-1)" "unprognostic (3.80e-2)" 8.3 38.9 13.9 6.6 14.6 9.3 18.6 11.8 14.2 15.5 20.4 9.4 6.0 13.5 35.9 13.0 23.2 15.5 11.5 14.9 19.3 13.6 13.2 8.9 4.3 14.0 14.4 68.9 12.0 22.5 22.4 6.8 12.7 23.6 9.9 37.4 10.0 18.6 2.6 8.8 5.8 14.4 13.3 6.8 8.4 23.7 16.5 5.9 37.1 4.2 5.0 16.4 5.0 13.4 19.8 28.1 16.7 16.2 35.1 43.5 14.0 24.0 37.6 31.8 21.5 7.9 37.2 8.7 20.6 30.3 19.3 28.5 18.1 19.4 32.2 6.6 7.3 5.5 9.1 11.1 25.4 10.6 1.9 27.3 23.9 23.0 19.9 30.4 19.3 11.6 20.5 9.8 27.3 33.9 10.9 10.2 8.9 10.3 27.0 3.3 23.0 5.2 31.3 30.6 19.6 118.5 38.0 21.3 22.4 11.5 52.6 8.3 11.7 22.6 11.9 20.2 16.6 1.2 6.8 3.8 33.3 2.8 9.9 13.8 0.7 3.8 0.4 0.9 0.6 0.4 0.5 0.5 1.9 2.2 0.2 0.4 0.7 1.7 1.5 0.7 0.0 0.5 13.9 14.6 11.8 14.2 14.9 19.3 14.0 14.4 12.7 13.3 16.5 13.4 3.7 3.2 9.0 38.8 2.1 8.8 8.0 12.3 19.4 17.0 11.7 9.1 6.0 10.0 11.2 9.2 39.6 10.2 0.6 4.3 13.7 13.5 8.1 24.1 10.6 4.9 10.8 4.8 51.1 6.2 9.7 12.8 6.1 11.7 0.0 66.8 5.3 8.0 6.7 20.2 53.4 6.1 6.1 3.5 6.6 7.4 19.6 4.4 7.2 14.0 0.4 12.5 1.0 51.3 21.3 7.8 2.4 25.2 3.7 4.9 2.3 15.5 28.3 41.7 19.7 5.8 12.2 14.6 6.9 8.3 6.5 1.8 1.2 69.0 6.6 4.7 TTLL12 KIAA0153 ENSG00000100304 "Tubulin tyrosine ligase like 12" Q14166 22 43166622-43187134 "Plasma proteins, Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 104.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 56.3;Paneth cells: 56.9;Squamous epithelial cells: 60.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003054, CAB046029" Approved Approved "Plasma membrane,Cytosol" NA NA 140000 "Cluster 39: Non-specific - mRNA processing" "Cluster 37: Intestine - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol "Plasma membrane" "CAB046029: AB_11128395, HPA003054: AB_2666770" "unprognostic (2.45e-2)" "unprognostic (3.47e-2)" "unprognostic (7.37e-3)" "unprognostic (5.40e-2)" "unprognostic (2.65e-1)" "unprognostic (3.50e-1)" "prognostic unfavorable (2.84e-4)" "unprognostic (5.81e-3)" "unprognostic (2.24e-1)" "unprognostic (6.08e-2)" "unprognostic (4.75e-2)" "unprognostic (1.73e-1)" "unprognostic (1.15e-1)" "unprognostic (1.17e-3)" "unprognostic (1.40e-1)" "unprognostic (6.66e-2)" "unprognostic (2.81e-2)" 13.9 28.1 8.7 16.6 8.5 26.2 13.0 10.0 15.1 25.8 1.8 35.6 24.4 13.9 3.6 104.5 13.9 18.5 10.2 9.5 9.7 9.0 21.0 9.3 11.2 16.2 8.7 23.7 19.2 9.4 14.7 7.2 15.8 15.2 19.5 4.7 21.9 6.8 12.6 36.8 22.9 7.1 6.5 10.7 33.4 25.7 8.1 8.0 9.1 7.9 12.9 15.5 37.0 9.1 113.2 46.7 18.5 45.9 27.8 19.0 59.7 36.3 12.8 34.1 17.8 76.2 62.7 107.9 43.0 30.3 16.7 78.8 77.3 66.5 8.7 13.6 123.3 26.5 73.6 66.4 43.5 120.2 26.4 30.2 79.3 40.8 43.4 18.3 36.5 52.1 166.1 24.8 16.1 104.4 84.1 65.2 67.4 78.9 46.1 84.4 63.5 155.6 28.7 36.6 56.2 23.2 77.1 111.2 41.6 8.4 44.0 52.9 35.2 22.7 31.7 44.1 51.4 41.6 55.4 81.0 25.7 60.8 31.4 0.0 2.3 0.3 2.6 1.2 2.5 1.8 2.5 1.9 1.8 1.1 2.4 1.7 0.6 2.3 1.7 1.6 1.8 1.9 8.7 8.5 10.0 15.1 9.5 9.7 16.2 8.7 15.8 6.5 8.1 9.1 3.7 6.4 6.7 3.6 6.4 11.2 11.4 11.0 17.1 8.5 13.5 9.9 4.5 17.2 7.6 7.3 4.2 8.8 3.2 56.3 5.9 14.2 1.0 5.0 9.5 5.8 9.1 39.1 8.0 8.6 19.0 6.0 34.1 14.7 0.0 14.3 8.2 35.0 9.8 0.0 8.5 30.6 10.2 14.2 2.9 2.6 8.7 7.5 10.6 1.9 7.7 4.2 4.1 3.0 2.2 25.8 56.9 17.0 9.4 28.7 32.1 8.3 5.0 5.6 0.0 5.2 7.2 2.0 12.2 60.2 18.2 4.1 5.9 13.4 39.9 13.7 TTLL2 "C6orf104, dJ366N23.3, NYD-TSPG" ENSG00000120440 "Tubulin tyrosine ligase like 2" Q9BWV7 6 167325071-167359503 "Predicted intracellular proteins" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "testis: 18.4" "Group enriched" "Detected in some" 184 "Early spermatids: 389.3;Late spermatids: 274.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "CACO-2: 1.9" "Not detected" "Not detected" HPA027985 Approved "Nuclear membrane,Nucleoli" NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 39: CACO-2 - Unknown function" "Cluster 34: Spermatids - Unknown function" "Nuclear membrane, Nucleoli" "HPA027985: AB_2211832" "unprognostic (5.98e-2)" "unprognostic (1.51e-1)" "unprognostic (2.47e-1)" "unprognostic (6.69e-2)" "unprognostic (1.02e-1)" "unprognostic (1.79e-1)" "unprognostic (5.29e-2)" "unprognostic (9.47e-4)" "unprognostic (7.57e-2)" "unprognostic (2.63e-4)" "unprognostic (3.50e-2)" "unprognostic (2.39e-1)" "unprognostic (8.14e-3)" "unprognostic (1.94e-1)" "unprognostic (8.02e-2)" 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.1 1.6 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 18.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 389.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 274.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TTLL7 FLJ23033 ENSG00000137941 "Tubulin tyrosine ligase like 7" Q6ZT98 1 83865024-83999150 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein, Ligase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 57.1" "Cell type enriched" "Detected in many" 6 "Oligodendrocytes: 1558.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HDLM-2: 28.4;RH-30: 22.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052249 Approved NA NA "Cluster 10: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA052249: AB_2681773" "unprognostic (9.68e-2)" "unprognostic (3.78e-1)" "unprognostic (3.15e-1)" "unprognostic (2.82e-2)" "unprognostic (6.56e-2)" "unprognostic (1.30e-1)" "unprognostic (1.25e-3)" "unprognostic (1.95e-1)" "unprognostic (3.06e-1)" "unprognostic (3.63e-2)" "unprognostic (7.93e-4)" "unprognostic (4.34e-1)" "unprognostic (1.84e-3)" "unprognostic (3.32e-1)" "unprognostic (2.67e-2)" "unprognostic (3.77e-3)" "unprognostic (1.04e-3)" 4.2 1.5 17.9 1.3 34.5 0.0 1.4 16.5 23.5 2.3 0.2 4.0 1.7 4.4 1.4 3.2 5.8 4.0 3.8 16.5 19.0 0.8 1.1 3.0 0.1 18.9 22.7 1.3 4.4 1.4 7.7 0.0 23.1 5.4 2.2 8.2 2.7 2.7 3.4 0.7 1.8 7.5 11.7 0.4 3.7 5.0 20.8 0.1 1.6 1.7 0.2 5.3 2.5 57.1 3.4 0.2 2.5 4.5 2.1 5.0 0.0 7.1 2.8 2.5 4.7 0.0 0.5 0.0 2.1 6.6 10.2 0.1 5.0 2.5 3.8 28.4 3.6 4.1 5.5 0.1 1.1 0.2 0.5 1.5 0.2 3.9 0.1 7.4 2.8 0.1 0.0 10.3 10.3 0.0 0.0 0.0 2.0 0.0 3.5 0.0 22.1 0.0 0.4 1.8 13.9 8.9 3.8 2.2 2.3 4.6 3.1 0.2 0.4 3.8 1.5 0.6 7.7 3.5 6.6 0.2 5.2 0.0 5.6 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.9 34.5 16.5 23.5 16.5 19.0 18.9 22.7 23.1 11.7 20.8 57.1 3.9 67.3 7.5 12.4 3.9 3.2 18.8 2.1 0.6 138.6 6.9 4.8 16.8 17.2 7.7 7.3 73.0 0.7 0.9 1.8 1.9 18.2 211.6 36.3 6.8 6.1 27.6 0.0 230.3 7.6 0.2 14.2 10.2 1.7 25.3 2.7 3.9 2.4 0.5 95.9 216.6 5.3 4.1 0.3 7.7 38.6 10.8 2.6 17.8 16.9 0.6 19.1 2.1 113.6 1558.6 4.3 4.7 84.7 12.5 22.5 0.4 13.8 30.8 118.4 19.7 68.0 44.9 68.2 45.7 2.7 2.0 0.7 3.0 1.1 1.3 26.5 TTLL8 ENSG00000138892 "Tubulin tyrosine ligase like 8" A6PVC2 22 50015123-50056935 "Predicted intracellular proteins" Ligase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 39 "testis: 4.2" "Group enriched" "Detected in some" 42 "Cardiomyocytes: 1.8;Early spermatids: 4.6;Late spermatids: 6.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA016882 Uncertain NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 25: Spermatids - Spermatogenesis" "HPA016882: AB_10603223" "unprognostic (1.81e-1)" "unprognostic (1.08e-2)" "unprognostic (8.18e-2)" "unprognostic (1.21e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TUBD1 "FLJ12709, TUBD" ENSG00000108423 "Tubulin delta 1" Q9UJT1 17 59859479-59892945 "FDA approved drug targets, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Developmental protein" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 83.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004609, HPA023980, HPA027090" Approved Approved Nucleoplasm,Cytosol NA Yes "Cluster 13: T-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 11: Alveolar cells - Smell perception" "Nucleoplasm, Cytosol" "CAB004609: AB_628416, HPA023980: AB_1858456, HPA027090: AB_1858457" "unprognostic (1.92e-1)" "unprognostic (5.95e-2)" "prognostic favorable (2.04e-4)" "unprognostic (1.39e-1)" "unprognostic (1.32e-2)" "unprognostic (5.64e-2)" "prognostic unfavorable (1.00e-5)" "unprognostic (2.86e-2)" "unprognostic (8.87e-3)" "unprognostic (1.02e-1)" "unprognostic (1.77e-3)" "unprognostic (2.59e-1)" "prognostic unfavorable (6.06e-4)" "unprognostic (4.97e-2)" "unprognostic (1.63e-1)" "unprognostic (1.36e-1)" "unprognostic (8.83e-2)" 4.4 4.4 5.8 4.9 6.9 3.9 7.0 9.2 7.4 7.5 5.0 7.5 3.8 5.5 9.1 10.6 6.5 4.6 6.0 5.9 6.3 6.2 5.9 5.1 6.7 6.7 6.9 9.0 7.8 5.9 6.9 4.2 7.0 7.8 4.7 5.6 7.0 6.2 6.5 6.8 4.8 4.3 6.3 5.8 6.4 5.5 6.2 8.2 7.3 7.7 8.3 6.4 8.3 8.9 11.7 15.8 12.2 12.8 6.8 4.9 9.7 9.1 5.3 11.7 9.5 17.0 7.5 10.5 15.0 2.1 7.9 9.7 17.4 5.4 11.1 6.1 21.2 12.6 12.4 20.4 3.6 7.6 6.4 2.7 8.3 10.1 3.5 4.0 9.4 10.3 27.5 7.1 4.0 83.1 15.6 8.5 10.8 13.0 6.9 16.1 17.9 16.2 5.0 4.8 11.3 6.8 6.4 4.9 6.5 14.5 11.8 7.2 3.0 8.4 18.3 5.9 9.8 8.3 13.7 16.2 4.0 8.3 7.5 6.5 8.4 16.3 11.4 5.8 13.2 11.7 14.0 12.1 5.9 8.9 18.1 14.8 8.8 10.1 6.5 9.9 16.7 7.1 5.8 6.9 9.2 7.4 5.9 6.3 6.7 6.9 7.0 6.3 6.2 8.9 8.3 12.8 36.1 10.7 16.9 15.7 14.4 9.1 10.8 7.6 10.9 11.3 5.3 5.7 17.6 3.7 6.2 6.3 9.4 3.2 11.7 5.7 1.7 9.2 8.5 9.4 10.3 13.9 9.2 4.8 7.4 9.6 4.1 16.3 11.4 9.9 8.9 3.8 4.0 3.3 9.5 5.5 8.2 4.7 7.1 0.8 5.6 6.9 7.2 9.4 6.0 10.3 13.4 8.5 18.4 3.7 7.5 8.2 10.9 12.5 3.6 3.6 9.4 8.6 6.6 13.3 9.6 14.7 24.2 10.6 16.9 4.0 16.2 2.6 4.9 6.8 TUSC1 "CCDC89B, TSG-9" ENSG00000198680 "Tumor suppressor candidate 1" Q2TAM9 9 25676389-25678440 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 164.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEL: 38.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051426 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 36: HEL - Hemostasis" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles Nucleoplasm "HPA051426: AB_2681481" "unprognostic (9.84e-2)" "unprognostic (3.56e-1)" "unprognostic (2.58e-1)" "unprognostic (2.11e-3)" "unprognostic (9.41e-3)" "unprognostic (1.78e-1)" "unprognostic (4.79e-3)" "unprognostic (1.72e-2)" "unprognostic (5.71e-2)" "unprognostic (1.85e-3)" "unprognostic (9.14e-3)" "unprognostic (1.03e-2)" "unprognostic (1.89e-3)" "unprognostic (2.88e-2)" "unprognostic (1.08e-1)" "unprognostic (2.37e-1)" "unprognostic (2.21e-2)" 16.1 10.6 8.5 2.8 8.5 1.7 14.8 7.0 9.3 13.6 9.5 14.3 5.3 18.3 6.2 9.1 15.9 2.8 12.2 8.7 8.9 13.1 10.9 9.8 1.6 9.6 10.5 13.2 9.8 5.6 9.0 3.8 8.2 11.7 3.7 2.8 10.8 6.1 8.3 13.1 9.1 5.5 9.0 6.8 11.5 21.8 8.6 3.2 11.9 4.7 2.0 12.7 10.7 10.4 10.0 2.1 2.1 0.0 7.0 5.8 0.1 7.5 0.0 2.8 3.4 0.1 3.5 0.0 2.2 8.9 7.6 0.0 5.3 9.4 1.7 0.0 10.3 38.6 11.2 0.0 3.4 0.0 0.0 7.1 13.0 3.1 7.3 0.0 3.1 0.0 0.0 0.1 3.3 5.0 0.0 0.1 1.8 8.0 9.5 0.0 1.4 0.1 3.9 4.6 0.7 16.8 9.3 7.6 8.2 4.1 6.7 10.8 6.6 0.0 13.6 0.1 0.0 0.0 0.0 0.0 8.8 2.6 9.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 8.5 8.5 7.0 9.3 8.7 8.9 9.6 10.5 8.2 9.0 8.6 10.4 46.5 12.8 6.4 2.3 2.1 60.8 46.1 14.7 47.3 24.8 45.4 55.0 12.2 20.0 5.9 16.5 4.2 29.5 2.4 14.8 66.5 7.9 85.7 11.0 26.6 24.4 13.1 4.8 7.3 12.4 13.8 33.0 7.1 17.2 0.0 15.7 22.9 18.5 9.7 21.9 7.6 11.8 10.2 4.8 13.0 16.2 30.7 5.2 28.4 3.7 1.2 42.9 0.0 4.0 9.3 8.1 9.5 21.8 0.5 45.5 8.1 23.1 3.5 14.3 32.9 52.8 36.9 164.0 12.8 16.8 37.8 29.0 1.3 16.3 14.3 19.8 TWNK "C10orf2, FLJ21832, IOSCA, PEO, PEO1, TWINKLE, TWINL" ENSG00000107815 "Twinkle mtDNA helicase" Q96RR1 10 100987367-100994403 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA replication" "Helicase, Hydrolase" "Deafness, Disease variant, Neurodegeneration, Neuropathy, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast glandular cells: 6.8;Breast myoepithelial cells: 6.6;Ductal cells: 5.4;Endometrial stromal cells: 7.2;Granulosa cells: 7.1;Theca cells: 9.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002532 Uncertain NA NA "Cluster 44: Non-specific - Transcription" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" "HPA002532: AB_1078311" "unprognostic (8.10e-2)" "unprognostic (9.65e-2)" "unprognostic (1.16e-1)" "unprognostic (2.19e-2)" "unprognostic (2.81e-2)" "unprognostic (1.19e-1)" "unprognostic (7.82e-3)" "unprognostic (7.99e-2)" "unprognostic (1.22e-1)" "unprognostic (7.95e-2)" "unprognostic (7.52e-2)" "unprognostic (1.96e-2)" "unprognostic (9.46e-2)" "unprognostic (9.82e-3)" "unprognostic (1.64e-1)" "unprognostic (1.36e-1)" "unprognostic (1.45e-1)" 4.9 7.0 3.7 5.5 3.7 3.0 7.5 3.6 3.5 3.8 3.2 4.4 3.3 4.6 5.3 5.5 6.6 2.6 5.0 3.4 3.6 5.9 6.0 2.1 6.1 3.9 4.0 5.1 5.2 4.8 2.4 3.8 3.8 4.0 4.8 1.6 4.0 3.4 11.6 5.5 3.8 4.5 3.7 4.6 3.9 8.3 4.0 8.1 4.1 12.6 8.3 6.6 3.5 3.5 15.5 32.0 12.5 39.7 11.1 7.2 14.7 11.4 14.8 17.3 16.6 52.6 13.1 55.4 21.1 7.0 10.4 25.0 52.2 27.7 21.1 25.5 31.0 42.1 17.4 40.2 19.1 54.8 16.7 14.9 30.7 25.5 77.6 15.8 10.6 26.3 45.9 15.0 12.3 21.2 37.0 18.8 35.8 28.2 25.9 35.5 27.5 33.2 10.7 15.4 20.1 38.5 12.0 16.0 37.8 13.8 20.9 16.0 12.4 8.6 17.4 10.6 32.5 28.0 31.3 46.0 10.6 47.8 9.8 1.2 0.6 0.1 1.2 0.5 3.7 2.4 1.8 2.7 1.2 2.1 2.0 2.2 0.0 2.5 0.8 1.3 0.4 1.4 3.7 3.7 3.6 3.5 3.4 3.6 3.9 4.0 3.8 3.7 4.0 3.5 3.5 0.0 2.6 0.0 1.0 0.0 0.0 0.0 0.0 0.0 6.8 6.6 0.0 0.0 3.1 1.8 0.0 4.2 1.9 0.0 3.9 5.4 0.0 2.3 7.2 2.0 0.0 0.0 0.0 3.0 3.7 1.3 0.0 2.8 1.3 7.1 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.4 0.0 0.0 2.3 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 1.6 1.1 9.1 0.0 0.0 TXNDC2 SPTRX1 ENSG00000168454 "Thioredoxin domain containing 2" Q86VQ3 18 9885726-9889275 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 311 "testis: 105.2" "Group enriched" "Detected in some" 98 "Early spermatids: 307.9;Late spermatids: 125.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "K-562: 1.5;U-2 OS: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB016414, HPA018817" Enhanced NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 36: Testis - Spermatogenesis" "Cluster 1: K-562 - Erythropoiesis" "Cluster 29: Early spermatids - Spermatogenesis" "CAB016414: , HPA018817: AB_2241329" "unprognostic (1.21e-2)" "unprognostic (3.55e-3)" "unprognostic (6.31e-2)" "unprognostic (5.25e-2)" "unprognostic (1.33e-1)" "unprognostic (1.25e-1)" "unprognostic (6.13e-1)" "unprognostic (1.21e-1)" "unprognostic (3.17e-2)" "unprognostic (8.95e-3)" "unprognostic (3.75e-2)" "unprognostic (1.13e-2)" "unprognostic (1.88e-1)" "unprognostic (1.71e-1)" "unprognostic (2.18e-2)" 0.1 0.1 0.0 0.1 0.0 0.3 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 105.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.3 0.0 0.2 0.1 0.2 0.0 0.3 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.1 0.0 0.2 0.0 0.2 0.5 0.3 0.0 0.6 0.0 0.8 0.0 0.0 0.3 0.0 0.2 0.1 0.0 1.5 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.2 0.4 0.2 1.1 0.5 0.3 0.0 0.1 0.0 0.4 0.0 0.2 0.0 0.1 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 307.9 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 125.1 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.5 1.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 TXNDC8 "bA427L11.2, SPTRX-3, TRX6" ENSG00000204193 "Thioredoxin domain containing 8" Q6A555 9 110303476-110337884 "Cancer-related genes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 101 "testis: 21.9" "Group enriched" "Detected in some" 182 "Early spermatids: 357.8;Late spermatids: 590.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "THP-1: 1.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 43: THP-1 - Innate immune response" "Cluster 34: Spermatids - Unknown function" "unprognostic (1.50e-1)" "unprognostic (1.13e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 357.8 0.0 0.1 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 590.4 2.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TXNDC9 APACD ENSG00000115514 "Thioredoxin domain containing 9" O14530 2 99318982-99340702 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031844, HPA031845, HPA031846" Approved Enhanced Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 10: Non-specific - Unknown function" Cytosol "HPA031844: AB_10600838, HPA031845: AB_10670968, HPA031846: AB_10669916" "unprognostic (3.63e-3)" "unprognostic (4.26e-2)" "unprognostic (7.28e-2)" "unprognostic (3.12e-2)" "unprognostic (1.32e-1)" "prognostic unfavorable (4.31e-4)" "prognostic unfavorable (9.63e-7)" "unprognostic (2.06e-2)" "unprognostic (9.09e-2)" "unprognostic (1.42e-1)" "unprognostic (1.99e-1)" "unprognostic (1.37e-1)" "unprognostic (2.32e-1)" "unprognostic (2.47e-3)" "unprognostic (2.03e-1)" "unprognostic (1.14e-1)" "unprognostic (1.29e-1)" 18.7 17.9 10.0 21.3 10.8 17.5 28.7 11.0 13.2 19.3 10.4 24.6 18.4 16.6 25.9 26.1 18.1 18.6 28.6 10.8 11.7 28.8 27.2 20.1 29.2 11.6 11.5 10.7 10.9 15.4 11.3 23.5 11.9 19.6 26.3 11.0 15.1 16.1 18.2 19.0 17.6 24.4 11.8 18.6 18.5 17.8 10.9 26.1 24.8 16.2 34.0 24.9 14.1 12.5 78.3 27.6 55.0 27.7 55.8 57.8 65.8 83.1 79.5 88.5 85.0 71.1 55.5 58.0 66.9 72.6 77.0 52.7 55.2 88.2 102.6 44.0 53.5 60.4 34.5 77.0 54.2 71.8 44.2 53.0 76.7 74.3 53.8 46.1 101.9 32.1 73.0 51.1 103.7 41.5 43.4 63.6 43.4 46.4 68.7 32.5 53.0 56.4 123.9 62.6 37.1 31.5 41.7 56.2 93.7 69.8 64.3 60.9 69.4 65.1 62.7 40.6 62.6 21.2 37.1 65.6 51.9 76.8 58.6 110.6 54.1 61.1 56.7 60.5 70.2 69.1 66.6 64.4 60.3 57.6 61.9 62.5 53.5 77.7 82.6 60.9 91.2 87.0 10.0 10.8 11.0 13.2 10.8 11.7 11.6 11.5 11.9 11.8 10.9 12.5 46.6 9.6 13.4 8.8 33.4 35.2 29.7 137.1 25.0 11.3 21.5 26.3 27.6 25.8 67.0 36.8 8.4 75.7 31.3 26.2 84.1 79.8 75.7 37.3 29.9 46.2 20.9 47.8 13.3 69.4 82.5 29.2 22.4 25.5 17.7 21.0 38.2 24.4 56.9 13.5 12.8 25.7 91.6 25.4 31.3 21.1 27.7 30.2 26.6 4.7 55.5 26.9 44.3 12.5 16.7 84.5 21.6 23.3 31.8 24.0 21.9 121.5 72.8 19.8 26.3 17.8 89.3 52.8 42.7 29.4 38.9 81.3 35.1 40.1 26.6 21.9 U2AF2 U2AF65 ENSG00000063244 "U2 small nuclear RNA auxiliary factor 2" P26368 19 55654146-55674716 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010910, HPA041943, HPA043562" Supported Supported Enhanced "Nucleoplasm,Nuclear speckles" NA NA 73000 "Cluster 1: Neutrophils - Mixed function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "Nuclear speckles" Nucleoplasm "CAB010910: AB_262122, HPA041943: AB_2677760, HPA043562: AB_2678555" "unprognostic (2.37e-1)" "unprognostic (2.22e-1)" "unprognostic (3.12e-1)" "unprognostic (9.60e-2)" "unprognostic (6.94e-2)" "unprognostic (4.01e-2)" "prognostic unfavorable (1.54e-6)" "unprognostic (9.46e-2)" "unprognostic (1.36e-2)" "unprognostic (8.00e-2)" "unprognostic (3.33e-2)" "unprognostic (4.25e-3)" "unprognostic (2.19e-2)" "unprognostic (4.80e-2)" "unprognostic (9.88e-2)" "unprognostic (1.14e-1)" "unprognostic (3.08e-2)" 74.2 80.9 70.3 101.9 73.0 147.7 70.2 74.6 82.4 92.1 75.4 83.7 85.1 87.4 56.7 98.2 82.8 54.0 69.3 70.3 70.8 79.4 80.2 74.2 119.3 76.2 71.5 98.3 75.0 70.1 93.7 63.6 73.0 74.9 54.0 46.0 72.0 65.9 67.3 80.0 92.3 62.1 72.0 115.7 75.4 81.8 72.1 132.5 78.9 45.9 93.7 78.2 80.7 82.4 244.5 394.0 235.9 191.1 108.3 109.8 249.3 191.9 174.1 314.2 305.3 231.3 222.3 284.5 149.5 164.9 160.5 193.0 299.3 268.3 149.1 218.0 501.9 245.2 176.1 221.5 176.7 287.4 263.5 148.8 161.0 239.5 166.8 120.0 190.8 195.9 293.1 181.3 169.9 239.2 388.0 261.1 260.4 217.1 307.2 414.5 149.7 233.0 189.7 290.0 270.6 211.0 208.6 197.1 125.7 134.6 190.5 296.9 161.5 279.7 203.7 130.0 415.9 165.0 239.3 344.5 124.3 279.5 245.2 0.1 1.1 0.8 1.3 1.5 1.0 0.8 1.1 0.9 1.0 1.1 0.8 0.8 2.1 0.6 1.2 1.8 1.1 0.9 70.3 73.0 74.6 82.4 70.3 70.8 76.2 71.5 73.0 72.0 72.1 82.4 31.0 3.2 9.1 10.4 46.0 45.4 41.4 34.8 57.5 41.8 29.7 21.3 2.7 24.3 20.6 27.6 31.3 58.5 34.1 44.0 19.6 33.0 6.4 33.8 36.0 31.4 45.5 32.6 6.8 23.8 63.0 29.4 51.0 40.9 34.3 30.4 27.5 26.8 37.6 35.3 7.6 42.4 30.5 22.0 32.3 8.4 44.4 31.6 19.6 11.2 37.4 25.3 30.9 4.0 12.0 31.8 29.3 34.3 62.4 41.9 31.9 21.3 15.3 52.0 0.0 26.1 46.6 22.5 32.0 53.5 39.2 71.8 42.7 30.8 43.6 44.9 UBE2C UBCH10 ENSG00000175063 "Ubiquitin conjugating enzyme E2 C" O00762 20 45812576-45816957 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 78.5;lymphoid tissue: 113.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 129.6;Erythroid cells: 182.1;Extravillous trophoblasts: 449.1;Granulosa cells: 119.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "T-reg: 8.2" "Group enriched" "Detected in many" 5 "granulocytes: 2.1;NK-cells: 2.1;T-cells: 8.2" "Low cell line specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basal ganglia: 4.3;white matter: 11.4" "Low region specificity" "Detected in some" "CAB011464, HPA034569, CAB035990, HPA054975" Approved Approved "Plasma membrane,Cytosol" Yes Yes "Cluster 35: T-regs - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Cytosol" "CAB011464: AB_442965, CAB035990: , HPA034569: AB_2674226, HPA054975: AB_2682658" "unprognostic (1.45e-2)" "unprognostic (2.19e-1)" "unprognostic (1.06e-1)" "unprognostic (2.11e-3)" "unprognostic (2.54e-1)" "unprognostic (1.35e-1)" "prognostic unfavorable (6.24e-6)" "unprognostic (2.27e-3)" "unprognostic (2.59e-2)" "unprognostic (1.04e-1)" "prognostic unfavorable (6.91e-4)" "unprognostic (3.76e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.09e-1)" "unprognostic (3.61e-1)" "unprognostic (4.65e-2)" "unprognostic (2.68e-1)" 2.6 2.9 0.3 21.5 0.3 78.5 4.3 0.9 0.6 6.1 0.7 26.7 21.4 5.7 0.6 37.2 1.9 2.7 1.4 0.2 0.3 1.9 2.9 5.4 45.3 0.3 0.7 1.3 1.0 0.4 0.4 20.4 0.7 1.5 30.9 0.2 5.0 0.9 0.9 18.5 20.6 10.5 0.2 15.8 13.0 16.4 1.6 113.5 1.1 0.2 69.5 6.9 12.3 0.4 312.8 223.9 390.9 188.3 10.4 24.0 225.2 238.5 121.6 390.7 278.4 743.8 345.4 327.6 233.2 115.5 475.6 294.9 2.2 260.5 395.8 141.7 213.7 101.5 168.5 196.0 3.0 145.4 241.6 7.6 27.8 265.7 257.3 57.4 193.4 206.4 1.8 261.6 325.4 516.2 243.5 41.1 237.1 350.8 529.4 256.0 354.8 1.4 134.9 105.9 226.1 188.7 378.3 271.7 154.4 196.2 276.6 209.4 70.1 341.2 298.4 236.2 473.4 84.3 2.9 369.4 208.0 103.4 328.6 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.8 1.7 0.6 0.1 0.1 0.1 2.1 2.1 0.5 0.3 8.2 3.2 0.3 0.3 0.9 0.6 0.2 0.3 0.3 0.7 0.7 0.2 1.6 0.4 0.9 0.0 3.7 0.0 17.9 17.3 7.8 39.0 5.7 0.0 8.6 14.6 0.0 1.5 9.3 0.0 0.0 129.6 3.6 27.4 0.0 1.3 12.0 5.8 5.9 9.5 1.2 182.1 0.0 0.5 449.1 28.5 25.5 9.6 5.7 119.0 18.2 3.6 92.6 0.0 0.1 41.1 50.8 20.8 18.1 6.4 0.9 24.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 1.5 7.2 0.0 37.0 12.6 6.2 0.6 1.8 0.0 0.0 0.5 19.2 52.2 50.7 83.2 11.6 31.2 13.7 2.5 68.4 18.4 UBE2H "GID3, UBC8, UBCH" ENSG00000186591 "Ubiquitin conjugating enzyme E2 H" P62256 7 129830732-129952960 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Glandular and luminal cells: 365.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003302 Approved Approved Mitochondria NA NA 21000 "Cluster 24: B-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 44: Endometrium - Transcription" Mitochondria "HPA003302: AB_1858526" "unprognostic (1.15e-1)" "unprognostic (5.85e-2)" "unprognostic (5.67e-3)" "unprognostic (2.76e-1)" "unprognostic (2.25e-1)" "unprognostic (3.08e-2)" "unprognostic (1.13e-1)" "unprognostic (1.37e-1)" "unprognostic (9.43e-2)" "unprognostic (6.19e-2)" "prognostic unfavorable (2.33e-5)" "unprognostic (1.13e-1)" "unprognostic (3.73e-2)" "unprognostic (2.37e-1)" "unprognostic (1.12e-1)" "unprognostic (3.58e-1)" "unprognostic (1.23e-1)" 46.8 64.7 43.0 29.1 44.2 42.3 34.4 46.4 49.1 44.7 58.7 42.3 23.4 44.3 37.6 49.9 44.6 44.6 98.2 42.1 45.4 42.1 44.2 38.8 31.8 48.7 43.4 41.7 84.3 49.2 29.4 52.5 45.0 36.1 26.0 42.0 39.3 41.5 69.3 31.2 24.4 49.2 41.8 28.6 34.6 36.4 45.8 37.4 45.0 60.6 39.8 40.1 33.7 47.8 82.6 43.8 58.5 56.1 126.1 107.5 86.5 72.0 97.8 45.8 51.1 22.9 92.5 34.0 87.4 76.6 123.8 62.5 46.2 81.6 59.5 40.9 22.6 11.5 63.5 28.6 98.3 23.6 36.8 146.7 106.9 61.3 99.7 106.3 89.7 36.3 27.5 104.1 71.5 29.9 31.1 26.1 80.0 60.5 49.8 24.4 27.8 77.2 95.9 106.5 20.3 59.6 68.3 164.7 43.8 166.0 17.1 27.2 89.1 51.7 24.2 72.2 76.5 83.5 65.6 58.5 102.1 28.9 49.7 2.2 1.4 3.4 2.8 1.2 3.8 2.3 2.8 2.6 1.3 4.5 3.6 3.8 4.8 0.9 1.5 2.3 4.4 1.3 43.0 44.2 46.4 49.1 42.1 45.4 48.7 43.4 45.0 41.8 45.8 47.8 69.9 41.7 51.8 87.1 43.1 145.8 187.5 65.7 59.7 65.1 83.7 49.4 102.9 44.3 69.3 71.7 60.5 116.3 56.7 38.6 41.1 66.0 93.5 225.7 91.2 81.4 59.1 100.0 97.1 70.9 67.1 65.2 43.8 365.8 14.7 53.9 45.3 73.1 41.8 43.7 116.9 35.3 54.9 40.3 69.8 44.0 44.1 52.0 48.0 89.0 26.2 87.4 51.5 113.1 108.5 118.3 33.6 78.6 60.5 227.6 27.6 49.7 95.3 35.6 13.1 65.9 69.0 46.5 22.5 78.6 153.7 200.4 49.2 79.7 26.6 274.3 UBE2L5 UBE2L5P ENSG00000236444 "Ubiquitin conjugating enzyme E2 L5" A0A1B0GUS4 13 30422488-30429758 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Ligase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 55 "testis: 46.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA045609, HPA062415" Approved Uncertain Nucleoplasm,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 83: Testis - Spermatogenesis" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Cytosol" "HPA045609: AB_10961322, HPA062415: AB_2684756" "unprognostic (2.09e-1)" "unprognostic (1.18e-2)" "unprognostic (8.01e-3)" "unprognostic (6.41e-4)" "unprognostic (1.78e-1)" "unprognostic (7.13e-2)" "unprognostic (2.20e-1)" "unprognostic (1.65e-1)" "unprognostic (1.19e-1)" "unprognostic (6.49e-3)" "unprognostic (1.78e-1)" "unprognostic (8.00e-2)" "unprognostic (3.50e-2)" "unprognostic (9.37e-2)" "unprognostic (2.60e-1)" "unprognostic (2.44e-2)" "unprognostic (8.75e-2)" 0.5 0.2 0.2 0.2 0.1 0.3 0.4 0.4 0.4 0.4 0.0 0.3 0.2 0.8 0.2 0.2 0.5 0.1 0.2 0.2 0.0 0.1 0.2 0.2 0.3 0.0 0.0 0.2 0.2 0.0 0.2 0.1 0.0 0.4 0.1 0.2 0.2 0.2 0.4 0.7 0.2 0.4 0.0 0.2 0.2 46.5 0.0 0.2 0.2 0.0 0.2 0.3 0.3 0.1 0.1 0.0 0.1 0.2 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.2 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.2 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.2 0.2 0.2 0.1 0.1 0.0 0.0 0.4 0.5 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.2 0.1 0.0 0.1 0.0 0.3 0.1 0.1 0.5 0.0 0.1 0.1 0.1 0.1 0.2 0.0 0.3 0.1 0.2 0.0 0.4 0.2 0.3 0.2 0.7 0.2 0.6 0.2 0.3 0.3 0.4 0.2 0.3 0.4 0.4 0.3 0.3 0.4 0.7 0.2 0.1 0.4 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 UBQLN3 TUP-1 ENSG00000175520 "Ubiquilin 3" Q9H347 11 5507300-5509958 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 396 "testis: 158.8" "Group enriched" "Detected in some" 70 "Early spermatids: 709.6;Late spermatids: 1878.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA020547, HPA062018" Enhanced NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 25: Spermatids - Spermatogenesis" "HPA020547: AB_1858577, HPA062018: AB_2684661" "unprognostic (3.79e-3)" 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 158.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.1 0.1 0.2 0.4 0.3 0.3 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 709.6 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1878.4 9.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 18.3 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 UBQLNL "MGC20470, MGC26958" ENSG00000175518 "Ubiquilin like" Q8IYU4 11 5514393-5518431 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "testis: 31.8" "Group enriched" "Detected in some" 76 "Early spermatids: 169.6;Late spermatids: 637.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (2.86e-1)" "unprognostic (1.79e-1)" "unprognostic (2.98e-4)" "unprognostic (1.43e-1)" "unprognostic (6.17e-2)" "unprognostic (7.60e-2)" "unprognostic (7.69e-2)" "unprognostic (2.22e-2)" "unprognostic (3.64e-1)" "unprognostic (1.17e-3)" "unprognostic (1.73e-1)" "unprognostic (1.54e-1)" "unprognostic (1.52e-8)" "unprognostic (1.17e-1)" "unprognostic (9.16e-2)" "unprognostic (1.17e-1)" "unprognostic (9.69e-5)" 0.7 0.7 0.5 0.1 0.4 0.3 0.5 0.3 0.5 1.5 0.6 0.7 0.1 0.9 1.2 0.4 1.2 0.2 0.6 0.4 0.6 1.3 0.9 0.8 0.3 0.6 0.6 2.4 0.7 0.1 0.6 0.2 0.6 1.5 0.1 0.0 0.4 0.1 0.1 0.5 0.8 0.3 0.5 1.5 0.5 31.8 0.4 0.4 1.1 0.0 0.1 0.7 0.8 0.5 0.0 0.0 0.1 0.0 0.2 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.5 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.3 0.5 0.4 0.6 0.6 0.6 0.6 0.5 0.4 0.5 0.3 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.0 0.1 0.2 0.3 0.4 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.2 169.6 0.5 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 1.5 1.1 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 637.7 5.3 0.3 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.1 0.2 2.6 0.1 0.3 0.0 0.4 0.5 0.0 0.0 0.3 0.2 4.0 2.6 0.0 0.1 0.3 0.1 0.3 0.2 0.2 UBR4 "KIAA0462, KIAA1307, RBAF600, ZUBR1" ENSG00000127481 "Ubiquitin protein ligase E3 component n-recognin 4" Q5T4S7 1 19074510-19210266 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction, Ubl conjugation pathway" "Calmodulin-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 271.0;Suprabasal keratinocytes: 252.9;Urothelial cells: 236.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 39.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013394, HPA021046" Approved Supported Nucleoplasm,Centrosome,Cytosol NA NA 15000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 31: Skin - Epidermis development" "Cluster 21: OE19 - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "Centrosome, Cytosol" "HPA013394: , HPA021046: AB_1858578" "unprognostic (1.37e-1)" "unprognostic (2.57e-2)" "unprognostic (2.82e-2)" "unprognostic (2.02e-1)" "unprognostic (8.78e-2)" "unprognostic (9.77e-2)" "unprognostic (1.14e-3)" "unprognostic (3.09e-1)" "unprognostic (1.96e-1)" "unprognostic (9.14e-3)" "unprognostic (7.48e-2)" "unprognostic (2.53e-1)" "unprognostic (7.68e-3)" "unprognostic (4.30e-1)" "unprognostic (1.19e-1)" "unprognostic (5.58e-2)" "unprognostic (1.52e-1)" 56.2 62.8 48.2 23.0 46.0 79.8 49.8 38.7 48.4 57.4 47.6 69.6 20.9 61.7 35.7 55.4 52.3 29.6 58.7 45.8 46.0 74.7 82.7 71.9 25.7 51.5 46.4 75.3 53.5 35.5 70.7 27.5 54.9 67.2 22.7 44.6 48.0 27.0 129.1 161.9 59.7 26.0 35.2 62.8 70.6 105.3 45.9 34.6 56.5 45.0 25.7 90.0 59.2 44.7 61.4 60.7 53.5 39.7 97.6 50.0 46.2 46.5 48.8 49.5 44.7 97.2 51.3 36.6 42.3 61.7 43.3 40.8 42.3 46.3 46.0 30.6 37.5 83.8 63.3 64.1 68.6 51.9 53.4 45.0 57.9 100.8 96.3 48.1 54.9 63.7 58.5 32.9 47.6 43.6 24.7 62.9 43.5 124.3 33.6 34.0 41.7 31.0 44.7 35.2 37.7 37.4 55.0 31.1 39.9 48.6 21.7 40.4 85.9 57.4 36.1 69.0 52.8 38.8 25.2 41.5 39.3 79.3 50.3 39.8 28.7 4.7 4.9 5.9 4.2 7.4 4.4 2.9 14.2 4.0 3.9 3.7 15.4 4.4 2.1 6.5 3.4 8.3 48.2 46.0 38.7 48.4 45.8 46.0 51.5 46.4 54.9 35.2 45.9 44.7 28.1 35.3 37.6 85.5 30.3 271.0 124.6 28.9 28.5 57.5 22.1 23.9 19.1 37.1 30.4 31.3 152.2 24.7 34.2 31.6 13.7 41.3 21.4 39.8 32.0 30.8 17.5 48.4 58.9 40.9 17.0 32.2 44.9 50.4 19.6 32.9 31.1 94.1 63.2 79.1 61.8 29.2 12.2 43.0 48.7 28.7 30.7 46.4 49.8 34.7 64.4 28.8 21.6 51.8 44.5 61.0 16.7 35.7 26.4 59.1 57.9 135.6 39.1 48.5 19.7 28.3 30.1 44.8 21.0 28.0 252.9 33.9 32.7 34.5 20.1 236.5 UBTD2 "DC-UbP, MGC30022" ENSG00000168246 "Ubiquitin domain containing 2" Q8WUN7 5 172209646-172283764 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 76.1;Late spermatids: 130.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035891, HPA035892" Uncertain NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "HPA035891: AB_2674846, HPA035892: AB_10670670" "unprognostic (2.89e-1)" "unprognostic (1.66e-1)" "prognostic favorable (5.92e-5)" "unprognostic (3.45e-2)" "unprognostic (2.03e-1)" "unprognostic (1.62e-1)" "prognostic unfavorable (1.44e-5)" "unprognostic (1.50e-2)" "unprognostic (1.08e-1)" "unprognostic (9.12e-2)" "unprognostic (1.05e-1)" "unprognostic (2.33e-1)" "unprognostic (5.92e-2)" "unprognostic (5.12e-2)" "unprognostic (2.24e-1)" "unprognostic (1.79e-1)" "unprognostic (1.52e-1)" 13.5 11.4 7.6 8.7 9.0 1.6 17.5 24.7 9.5 24.6 8.7 15.0 18.4 21.0 9.3 10.6 12.0 16.1 10.3 7.9 8.4 15.6 15.7 13.2 9.2 8.4 8.2 21.1 12.5 11.1 7.0 17.1 8.3 13.4 15.8 9.2 11.9 12.7 9.8 9.9 22.1 17.9 7.9 7.2 12.2 35.4 7.8 12.0 11.5 15.7 10.2 14.5 11.3 8.3 21.9 16.7 78.1 61.0 48.1 42.9 38.0 27.8 33.2 29.9 43.8 36.5 15.9 18.7 23.5 43.6 51.4 15.1 41.7 30.3 40.1 18.0 30.3 5.7 17.6 28.4 32.6 13.3 10.3 33.1 37.1 31.9 25.7 25.8 36.5 28.8 2.3 7.5 28.6 23.8 23.7 27.8 33.4 19.0 21.1 43.5 38.0 7.2 36.3 23.0 22.9 57.9 30.1 27.0 28.4 39.9 23.3 21.7 26.6 39.6 29.2 21.0 23.9 6.8 19.9 17.8 13.9 18.2 31.0 0.0 0.3 0.0 0.2 0.4 0.3 0.2 0.2 0.1 0.4 0.2 0.3 0.2 0.0 0.1 0.2 0.7 0.5 0.1 7.6 9.0 24.7 9.5 7.9 8.4 8.4 8.2 8.3 7.9 7.8 8.3 15.2 6.4 4.8 14.0 3.7 22.0 25.7 12.8 15.9 8.4 22.2 12.1 5.5 11.5 11.9 9.2 0.0 9.8 5.6 22.8 17.6 14.5 76.1 9.7 28.3 12.3 8.9 0.0 14.9 12.0 21.7 31.4 8.6 23.6 0.0 14.2 13.9 15.1 6.8 25.2 22.5 12.2 14.2 6.5 44.5 130.9 24.8 9.8 14.2 9.4 5.8 16.2 1.0 25.6 19.8 21.6 9.8 21.1 2.9 29.8 20.5 17.2 6.8 3.4 6.6 16.7 19.6 5.8 9.7 17.0 18.8 8.1 4.0 11.9 13.7 39.6 UFSP2 "C4orf20, FLJ11200" ENSG00000109775 "UFM1 specific peptidase 2" Q9NUQ7 4 185399537-185425979 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 190.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039985, HPA043298" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 54: Non-specific - Microtubule organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA039985: AB_10794206, HPA043298: AB_10795037" "unprognostic (8.87e-2)" "unprognostic (1.85e-2)" "unprognostic (1.52e-1)" "unprognostic (1.97e-1)" "unprognostic (1.17e-1)" "unprognostic (1.29e-1)" "unprognostic (3.63e-2)" "unprognostic (3.19e-2)" "unprognostic (3.69e-1)" "unprognostic (1.50e-1)" "unprognostic (2.04e-2)" "unprognostic (2.56e-1)" "prognostic favorable (1.07e-8)" "unprognostic (1.92e-1)" "unprognostic (8.12e-2)" "unprognostic (9.36e-3)" "unprognostic (6.70e-3)" 21.2 24.9 19.9 9.5 21.7 5.7 24.3 25.2 24.1 21.6 29.6 19.5 13.0 19.9 28.1 25.8 17.7 15.6 32.1 20.4 21.9 37.3 24.1 17.1 11.9 20.4 20.2 31.4 19.7 23.8 10.0 14.0 20.9 19.8 15.3 56.4 20.3 19.2 48.5 21.6 12.0 20.2 20.7 14.5 17.5 21.0 21.3 14.3 25.9 40.6 16.1 16.2 10.1 25.3 17.5 11.9 28.8 24.3 25.8 25.6 15.3 20.3 20.5 19.3 19.3 18.4 23.2 17.9 9.0 19.7 14.7 16.1 20.4 32.2 17.4 21.8 12.4 11.8 13.0 23.3 30.2 15.3 12.3 14.7 26.8 16.5 16.7 26.7 35.7 21.9 24.8 34.3 28.2 16.3 22.0 16.4 8.7 11.8 16.7 20.2 11.5 20.4 31.9 11.4 18.6 14.8 11.3 25.6 23.1 17.6 15.4 13.6 27.3 9.5 16.8 7.5 17.2 34.6 14.8 9.5 30.5 11.0 25.3 10.8 12.3 7.6 21.2 10.4 25.7 22.0 21.7 24.1 14.1 15.4 23.2 22.9 0.7 21.5 11.1 19.9 20.6 12.5 19.9 21.7 25.2 24.1 20.4 21.9 20.4 20.2 20.9 20.7 21.3 25.3 33.8 6.4 23.9 14.7 30.1 22.0 28.7 35.1 33.0 47.6 20.9 25.5 27.0 15.7 31.1 20.2 66.7 26.0 23.4 8.3 111.6 28.3 190.5 16.4 28.9 24.1 19.3 24.0 12.2 33.1 29.7 34.2 20.4 19.2 29.7 21.9 21.8 17.3 27.2 18.5 17.8 18.6 28.5 22.1 18.8 52.9 35.4 18.5 35.6 12.2 17.3 71.8 21.6 23.6 33.2 19.7 14.6 42.2 53.0 15.4 22.2 100.9 23.7 87.9 65.7 31.8 38.9 89.3 56.7 22.6 18.9 41.9 27.1 35.6 14.8 19.6 UHRF1 "FLJ21925, ICBP90, Np95, RNF106, TDRD22" ENSG00000276043 "Ubiquitin like with PHD and ring finger domains 1" Q96T88 19 4903080-4962154 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair, Transcription, Transcription regulation, Ubl conjugation pathway" "Chromatin regulator, DNA-binding, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "bone marrow: 27.0;lymphoid tissue: 67.2" "Cell type enhanced" "Detected in many" "Erythroid cells: 49.7;Plasma cells: 21.0;Squamous epithelial cells: 15.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 4.8" "Group enriched" "Detected in many" 4 "dendritic cells: 4.8;T-cells: 2.3" "Cell line enhanced" "Detected in all" "MOLT-4: 450.9;REH: 1004.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA049408, HPA055446" Enhanced Supported Nucleoplasm No Yes "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 14: REH - Unknown function" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA049408: AB_2756317, HPA055446: AB_2732597" "unprognostic (3.83e-2)" "unprognostic (6.83e-3)" "unprognostic (5.13e-2)" "unprognostic (1.69e-1)" "unprognostic (1.40e-1)" "unprognostic (7.21e-2)" "prognostic unfavorable (1.63e-4)" "unprognostic (4.30e-2)" "prognostic unfavorable (6.81e-4)" "unprognostic (2.82e-1)" "prognostic unfavorable (4.52e-5)" "unprognostic (2.33e-3)" "unprognostic (0.00e+0)" "unprognostic (3.75e-3)" "unprognostic (2.45e-1)" "unprognostic (2.01e-1)" "unprognostic (2.02e-1)" 1.0 0.9 2.1 9.6 2.7 27.0 1.7 2.1 2.3 1.6 1.8 2.9 3.7 1.0 0.1 6.5 0.4 0.8 0.5 2.0 2.2 0.6 0.9 1.3 15.8 2.8 2.8 0.3 0.6 0.2 0.2 2.1 2.7 0.6 2.6 0.4 1.5 0.2 1.2 3.4 3.9 1.9 1.9 3.7 3.3 5.2 3.5 67.2 0.3 0.3 10.3 1.6 2.5 4.6 111.3 78.7 116.6 83.4 3.3 13.3 18.5 88.3 42.0 89.9 86.8 94.6 54.9 62.7 21.1 39.4 32.7 54.1 81.2 47.7 63.0 102.7 92.2 54.3 74.3 102.4 1.3 135.1 78.9 6.5 3.5 48.9 12.6 14.1 27.2 97.2 79.3 70.5 54.5 86.7 450.9 82.5 52.5 40.0 84.3 1004.5 259.7 45.4 24.9 80.1 86.0 68.5 69.2 37.7 12.1 18.8 68.2 127.6 34.2 94.6 76.7 124.3 108.3 29.8 33.1 183.5 54.8 129.7 123.3 0.3 0.2 0.1 0.6 0.0 0.0 0.2 0.8 1.0 1.3 0.1 0.2 0.8 0.8 0.5 0.2 4.8 2.3 0.6 2.1 2.7 2.1 2.3 2.0 2.2 2.8 2.8 2.7 1.9 3.5 4.6 0.2 0.0 0.0 1.6 2.1 0.0 0.8 0.0 3.4 2.5 4.4 2.8 4.3 1.5 0.6 0.0 0.0 6.6 6.9 2.6 0.0 2.2 2.9 1.3 1.8 2.2 0.0 49.7 0.4 0.4 7.8 4.7 8.6 2.4 0.0 10.4 0.4 0.7 8.9 3.3 0.4 2.3 0.0 1.9 0.0 1.8 0.6 3.8 0.0 0.0 2.0 0.6 1.0 3.0 1.3 4.2 1.9 0.4 21.0 0.6 1.4 0.2 0.7 0.7 0.0 1.2 6.1 6.1 11.9 15.8 0.0 1.4 3.7 1.5 8.3 1.3 UNG "DGU, HIGM4, UDG, UNG1, UNG2" ENSG00000076248 "Uracil DNA glycosylase" P13051 12 109097597-109110992 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 64.9;Spermatogonia: 74.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB011605 Uncertain Approved Cytosol NA Yes "Cluster 16: MAIT-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "CAB011605: AB_778737" "unprognostic (4.38e-2)" "unprognostic (3.82e-3)" "unprognostic (1.03e-2)" "unprognostic (1.33e-2)" "unprognostic (4.64e-1)" "unprognostic (4.10e-2)" "prognostic unfavorable (6.40e-4)" "unprognostic (5.68e-3)" "prognostic unfavorable (3.06e-4)" "unprognostic (4.66e-2)" "unprognostic (8.78e-3)" "unprognostic (1.91e-1)" "unprognostic (1.35e-3)" "unprognostic (2.57e-2)" "unprognostic (4.50e-1)" "unprognostic (1.40e-2)" "unprognostic (6.89e-2)" 19.8 56.7 32.4 14.7 32.4 16.0 23.1 30.1 34.8 16.6 27.7 28.0 17.1 14.5 12.7 29.7 15.6 10.4 21.1 29.2 34.9 27.5 32.2 9.6 18.0 32.2 31.4 15.7 12.4 33.2 10.9 17.8 34.1 13.6 29.3 6.8 17.7 17.6 43.0 32.7 18.8 14.5 31.6 16.1 17.7 24.3 33.5 22.8 22.2 33.5 27.0 13.5 20.1 30.8 77.1 77.5 72.8 66.6 118.6 33.8 69.5 44.4 30.1 68.6 52.3 61.7 51.6 100.3 65.1 40.2 35.9 47.6 81.4 46.0 66.4 85.6 150.9 98.1 41.1 105.5 17.7 147.6 58.2 30.7 41.6 33.0 18.3 54.6 50.4 117.8 80.9 32.5 47.0 96.2 136.8 173.6 130.0 124.2 117.7 123.9 109.8 85.9 43.4 95.6 103.3 57.4 79.6 67.8 39.5 94.2 126.2 68.2 26.0 59.1 52.7 39.3 62.5 62.6 145.0 190.5 44.8 97.7 73.8 12.9 2.7 5.0 22.4 5.3 31.6 16.0 25.5 25.6 6.8 17.2 16.4 18.4 0.0 16.5 5.5 4.9 25.5 14.4 32.4 32.4 30.1 34.8 29.2 34.9 32.2 31.4 34.1 31.6 33.5 30.8 26.6 0.0 4.8 16.0 9.2 18.0 11.0 13.2 25.0 2.6 21.7 14.1 12.4 7.2 5.0 42.3 4.2 64.9 12.5 14.7 19.6 14.4 3.4 7.6 15.0 17.7 8.4 32.4 7.0 6.2 38.1 12.6 14.3 9.9 7.6 24.8 20.3 20.8 18.3 5.0 6.2 21.4 10.2 3.8 5.4 4.2 14.0 5.5 14.2 6.5 3.8 15.8 7.2 6.6 4.0 5.0 10.3 14.7 16.7 6.8 9.3 20.2 3.2 3.5 6.6 10.2 11.5 21.9 74.6 37.8 20.9 20.4 15.3 25.7 40.4 9.7 UQCRFS1 "RIP1, RIS1, RISP, UQCR5" ENSG00000169021 "Ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1" P47985 19 29205320-29213151 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" Translocase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 231.6;tongue: 285.9" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1474.9;Distal tubular cells: 1035.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041863, HPA050339" Enhanced Approved Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA041863: AB_10794638, HPA050339: AB_2681095" "unprognostic (4.00e-2)" "unprognostic (2.23e-3)" "prognostic favorable (3.29e-4)" "unprognostic (7.91e-3)" "unprognostic (3.93e-2)" "unprognostic (8.68e-2)" "unprognostic (1.84e-1)" "unprognostic (7.53e-2)" "unprognostic (3.53e-2)" "prognostic unfavorable (3.84e-4)" "unprognostic (1.73e-2)" "unprognostic (1.66e-1)" "prognostic favorable (3.92e-9)" "unprognostic (6.11e-2)" "unprognostic (2.96e-1)" "unprognostic (1.45e-1)" "unprognostic (1.92e-2)" 28.7 50.1 25.6 17.4 26.7 52.8 24.7 29.4 31.1 18.3 33.6 49.0 43.2 19.2 23.1 33.2 19.3 13.2 138.3 27.2 28.4 62.5 50.9 17.6 17.2 27.0 27.4 15.4 29.4 47.3 19.9 17.3 26.1 18.8 52.6 26.6 26.7 21.9 231.6 27.9 34.0 24.8 26.4 21.1 39.3 25.9 29.3 26.0 16.8 285.9 25.9 25.7 20.3 26.0 63.0 103.7 37.7 34.1 60.6 45.9 41.8 47.8 49.7 64.7 71.1 63.3 37.7 56.7 49.2 54.4 52.7 64.8 83.4 56.9 77.6 38.7 83.2 80.2 39.2 58.1 51.3 77.2 67.5 55.5 60.4 44.2 66.9 38.0 52.4 69.0 58.0 34.5 70.2 58.0 54.5 57.6 39.6 132.2 39.7 48.9 50.3 43.1 80.9 74.4 45.8 22.4 43.5 84.9 58.2 42.0 39.6 63.4 33.4 43.5 66.4 30.2 50.4 16.4 33.3 52.5 38.4 66.4 31.7 51.4 90.7 43.8 50.0 90.9 50.3 54.8 53.2 51.9 106.6 48.0 56.1 53.6 27.3 49.2 78.3 59.3 68.4 166.2 25.6 26.7 29.4 31.1 27.2 28.4 27.0 27.4 26.1 26.4 29.3 26.0 69.7 54.5 46.6 16.6 104.9 147.6 279.7 466.7 105.9 71.8 119.5 128.4 1474.9 161.5 201.4 114.0 16.7 282.0 116.8 321.6 1035.0 245.2 258.4 106.1 66.8 106.8 160.0 147.9 18.1 235.1 271.7 126.7 139.7 88.5 90.7 114.2 83.9 272.1 266.1 52.2 19.2 293.6 317.3 160.6 109.6 146.0 92.2 136.6 165.4 13.1 206.6 124.6 132.8 19.6 15.8 205.0 225.8 81.6 159.4 257.3 338.6 758.4 132.4 84.1 98.6 107.5 131.0 348.8 80.5 203.9 160.3 381.9 109.5 209.1 407.4 372.1 URB2 "KIAA0133, NET10, NPA2" ENSG00000135763 "URB2 ribosome biogenesis homolog" Q14146 1 229626247-229660200 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 29.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008902, HPA046788" Uncertain Enhanced Nucleoli NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoli "HPA008902: AB_2213805, HPA046788: AB_2679807" "unprognostic (1.26e-1)" "unprognostic (4.03e-3)" "unprognostic (2.16e-2)" "unprognostic (3.63e-2)" "unprognostic (1.79e-1)" "unprognostic (2.48e-1)" "unprognostic (5.53e-3)" "unprognostic (1.67e-1)" "unprognostic (1.02e-1)" "unprognostic (1.17e-1)" "unprognostic (1.59e-1)" "unprognostic (2.61e-2)" "unprognostic (1.62e-3)" "unprognostic (7.81e-2)" "unprognostic (2.72e-1)" "unprognostic (1.69e-2)" "unprognostic (1.45e-1)" 4.9 2.8 2.2 3.9 2.6 4.5 3.2 2.6 2.4 2.1 1.9 2.6 2.2 3.2 1.8 3.7 2.8 2.6 2.6 2.0 2.3 2.2 2.8 2.1 4.5 2.6 2.7 2.9 4.7 2.5 4.3 3.3 2.5 2.0 2.4 2.6 2.3 1.8 6.9 3.0 2.5 3.3 2.6 3.0 2.7 5.7 2.5 4.6 2.2 4.5 4.7 4.9 2.2 3.1 13.6 20.1 12.8 17.2 7.9 6.5 39.1 10.6 6.6 16.1 12.1 20.1 10.4 28.0 11.9 7.6 8.6 18.3 32.0 13.0 14.6 13.8 30.4 17.5 16.8 11.9 7.5 25.8 14.5 6.4 9.3 16.0 12.4 4.1 7.8 16.2 37.7 12.7 10.1 10.7 29.0 12.6 43.1 24.1 13.2 32.0 18.2 27.9 7.1 17.0 19.1 23.4 12.5 12.9 10.6 4.4 14.6 14.6 8.6 13.1 16.6 16.8 30.8 13.9 14.4 41.6 7.0 19.0 24.4 0.1 0.9 0.2 1.2 1.7 2.2 0.8 1.1 1.4 1.1 1.0 1.6 1.3 0.1 0.8 0.6 0.7 1.4 1.4 2.2 2.6 2.6 2.4 2.0 2.3 2.6 2.7 2.5 2.6 2.5 3.1 5.4 0.0 1.1 3.6 6.0 10.1 8.6 1.8 4.0 6.4 5.1 4.3 2.7 1.5 2.6 5.5 29.2 5.3 4.5 2.0 0.0 2.4 0.4 2.8 5.0 4.6 6.6 6.9 7.1 2.7 11.7 3.6 4.1 3.2 0.0 3.5 3.9 3.7 2.8 3.3 7.2 2.5 4.1 1.3 2.7 0.9 2.1 2.8 5.4 6.5 2.7 2.6 2.1 10.1 7.0 2.7 0.8 3.4 4.4 8.7 0.6 2.3 1.3 16.7 0.0 11.6 4.0 8.0 4.0 5.5 9.1 3.3 4.2 3.1 3.1 5.5 USP11 UHX1 ENSG00000102226 "Ubiquitin specific peptidase 11" P51784 X 47232866-47248328 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Bipolar cells: 203.6;Horizontal cells: 139.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003103, HPA037536" Enhanced Supported Supported Nucleoplasm,Cytosol "Intracellular and membrane" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 56: Bipolar cells - Visual perception" Nucleoplasm Cytosol "HPA003103: AB_10671088, HPA037536: AB_10672904" "unprognostic (1.60e-1)" "unprognostic (2.77e-3)" "unprognostic (5.84e-2)" "prognostic unfavorable (2.95e-4)" "unprognostic (3.08e-2)" "unprognostic (2.02e-1)" "unprognostic (6.11e-3)" "unprognostic (9.21e-2)" "unprognostic (3.18e-2)" "unprognostic (3.52e-1)" "unprognostic (3.29e-3)" "unprognostic (3.74e-2)" "prognostic favorable (4.13e-5)" "unprognostic (3.14e-2)" "unprognostic (9.23e-2)" "unprognostic (9.51e-2)" "unprognostic (7.11e-2)" 25.5 32.8 117.7 23.7 118.7 11.2 26.8 41.5 116.3 51.2 30.0 33.9 11.5 47.0 23.6 18.2 49.9 24.5 45.5 113.1 148.1 33.3 12.7 30.9 30.1 69.8 78.3 76.4 27.1 36.6 103.7 24.9 93.9 33.4 14.1 84.8 21.4 38.7 32.4 18.5 25.5 35.9 65.4 29.3 24.9 46.2 122.8 42.6 52.2 29.6 28.9 36.9 31.7 79.8 45.6 70.7 117.6 81.0 43.4 28.5 33.0 34.0 52.5 65.6 73.3 67.4 36.7 29.9 26.1 60.5 70.5 53.5 94.7 24.0 56.4 47.1 73.5 34.7 52.9 61.4 50.7 39.2 70.7 42.1 9.8 69.1 29.3 37.3 26.7 68.9 26.6 3.9 51.8 70.0 77.8 43.4 89.2 24.3 62.5 86.1 114.3 25.1 32.4 60.9 66.8 114.4 62.6 12.4 37.7 73.9 26.0 23.0 28.2 56.0 58.0 79.3 39.6 54.3 36.2 51.3 34.3 48.8 50.8 63.9 9.1 19.9 55.4 19.6 48.3 53.1 24.5 54.3 11.9 53.1 36.6 76.3 5.5 56.4 24.3 53.2 35.0 46.0 117.7 118.7 41.5 116.3 113.1 148.1 69.8 78.3 93.9 65.4 122.8 79.8 13.6 22.4 17.7 25.8 53.5 13.6 42.2 30.9 21.6 203.6 13.0 23.5 24.2 7.2 31.5 33.1 56.3 20.9 52.2 9.4 50.9 18.3 26.4 28.2 26.3 22.5 35.4 18.3 43.3 10.2 15.0 41.3 22.4 28.3 45.7 56.6 22.1 8.2 13.4 139.7 63.7 8.7 28.5 12.0 16.3 41.0 29.5 17.9 28.4 19.7 17.5 96.2 23.7 25.1 24.8 12.5 7.9 42.2 48.1 18.6 4.7 15.2 46.4 63.4 26.3 57.2 40.2 18.3 87.8 11.9 6.5 16.3 44.6 34.2 8.9 26.0 USP13 IsoT-3 ENSG00000058056 "Ubiquitin specific peptidase 13" Q92995 3 179653032-179804366 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Autophagy, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 149.2;tongue: 108.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 208.5;Inhibitory neurons: 52.2;Theca cells: 58.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 15.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HDLM-2: 93.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004827 Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nucleoplasm, Cytosol" "HPA004827: AB_1080497" "unprognostic (1.00e-2)" "unprognostic (2.09e-1)" "unprognostic (5.82e-2)" "unprognostic (7.14e-2)" "unprognostic (9.94e-2)" "unprognostic (3.96e-2)" "prognostic unfavorable (2.40e-5)" "unprognostic (1.76e-1)" "unprognostic (4.55e-2)" "unprognostic (7.79e-2)" "unprognostic (1.69e-3)" "unprognostic (2.22e-2)" "prognostic unfavorable (3.46e-6)" "unprognostic (4.93e-2)" "unprognostic (9.79e-2)" "unprognostic (3.38e-2)" "prognostic unfavorable (3.06e-4)" 6.2 11.9 3.9 2.8 13.6 1.5 5.3 8.6 12.0 3.3 0.0 2.9 1.2 5.7 3.4 4.0 3.4 4.5 42.5 3.7 4.7 3.0 4.6 5.4 3.6 11.3 10.5 12.5 4.1 4.0 5.8 2.6 12.7 4.3 2.2 7.1 6.2 2.7 149.2 2.2 1.9 6.3 6.4 2.1 1.7 6.0 8.1 2.4 9.7 108.9 3.5 3.5 2.2 34.4 27.6 11.3 20.0 14.8 8.9 14.1 11.6 18.6 17.4 23.7 18.8 17.1 9.6 35.6 18.0 17.2 27.6 2.6 21.4 9.1 26.4 93.3 14.8 9.0 23.6 14.4 6.3 26.5 1.1 10.5 3.0 18.8 18.5 9.1 16.6 11.9 4.7 43.0 15.7 15.0 22.5 3.0 17.9 1.3 13.1 29.3 20.2 27.4 11.7 7.9 13.0 14.5 14.1 16.9 7.2 5.4 37.0 12.7 24.1 28.6 27.6 23.7 64.1 29.5 21.2 78.3 13.0 15.0 27.2 0.1 0.3 0.0 2.6 0.5 15.6 3.2 1.8 3.8 1.5 0.9 1.2 1.3 0.0 0.0 0.7 4.5 0.7 1.3 3.9 13.6 8.6 12.0 3.7 4.7 11.3 10.5 12.7 6.4 8.1 34.4 45.0 9.6 35.9 14.0 5.3 2.5 1.9 1.4 0.6 13.7 7.1 5.2 208.5 5.7 5.4 1.8 6.2 10.7 5.6 1.4 15.6 1.1 2.6 13.9 11.4 10.1 9.6 5.5 23.2 4.4 2.4 12.0 4.1 2.5 2.5 35.5 22.1 7.6 4.3 16.8 52.2 2.9 0.0 4.8 3.5 3.6 9.3 5.0 14.2 16.9 1.7 7.0 3.1 36.2 42.5 1.0 12.2 9.4 4.5 4.4 0.1 2.7 3.7 10.2 13.1 17.8 12.0 6.1 2.8 4.8 1.6 5.1 4.1 58.8 4.5 1.4 USP15 "KIAA0529, UNPH4" ENSG00000135655 "Ubiquitin specific peptidase 15" Q9Y4E8 12 62260338-62417431 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 176.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 297.9" "Lineage enriched" "Detected in all" 5 "granulocytes: 297.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006237, HPA006428, HPA071014" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 300000 "Cluster 1: Neutrophils - Mixed function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 1: K-562 - Erythropoiesis" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol "Nucleoplasm, Nuclear bodies" "HPA006237: AB_1080502, HPA006428: AB_2667588, HPA071014: AB_2686333" "unprognostic (8.18e-2)" "unprognostic (3.22e-1)" "unprognostic (9.63e-2)" "unprognostic (2.09e-1)" "unprognostic (1.10e-1)" "unprognostic (2.75e-1)" "prognostic unfavorable (8.04e-4)" "unprognostic (6.59e-2)" "unprognostic (7.70e-3)" "unprognostic (2.19e-1)" "unprognostic (2.47e-1)" "unprognostic (4.51e-2)" "prognostic unfavorable (1.58e-5)" "unprognostic (9.28e-2)" "unprognostic (5.81e-3)" "unprognostic (1.11e-2)" "unprognostic (1.26e-1)" 29.0 21.6 4.5 29.4 4.8 176.2 22.9 12.3 6.7 17.6 10.2 18.0 13.8 14.6 9.2 19.7 17.8 13.7 19.8 5.2 5.5 14.9 27.2 31.5 33.3 6.0 5.4 26.7 19.7 14.9 13.9 18.4 5.7 14.3 16.7 45.8 19.7 8.3 35.5 29.9 24.6 12.6 4.6 44.3 18.8 30.2 5.5 26.5 17.1 14.8 24.9 18.1 19.4 8.0 18.3 16.5 14.2 17.7 25.7 25.1 27.0 29.0 21.2 22.3 16.1 19.6 21.6 15.5 16.6 17.8 10.1 18.5 18.4 23.1 27.6 18.5 15.0 25.2 15.1 14.1 18.8 35.6 61.8 15.0 19.2 27.2 20.7 20.7 26.1 16.3 80.8 36.0 20.0 23.5 26.4 19.3 25.4 16.5 24.0 17.2 19.1 32.3 17.9 22.8 17.9 8.9 30.9 21.6 17.3 17.4 34.7 18.8 37.2 21.2 22.2 32.0 18.2 16.4 24.0 21.9 25.7 26.7 23.5 163.4 60.0 64.3 13.5 31.1 14.9 28.5 19.6 14.0 23.7 20.5 23.5 13.8 297.9 14.7 26.8 26.6 58.8 26.1 4.5 4.8 12.3 6.7 5.2 5.5 6.0 5.4 5.7 4.6 5.5 8.0 57.1 38.5 36.4 68.6 130.3 58.8 40.8 26.2 40.5 54.9 32.3 28.1 74.9 21.5 48.9 23.9 110.5 31.7 142.5 50.2 11.7 36.4 172.2 26.3 46.5 45.4 42.0 248.3 124.8 41.5 43.3 52.5 57.6 38.9 88.6 53.5 21.0 45.3 46.2 42.1 104.2 33.2 12.2 101.3 97.6 172.0 61.8 120.6 53.4 135.9 195.8 25.6 90.6 100.0 108.8 55.1 47.6 29.3 94.3 36.0 30.9 25.9 31.9 151.5 39.5 66.1 60.5 83.7 43.3 49.3 77.0 65.8 130.0 27.0 29.5 60.8 USP29 ENSG00000131864 "Ubiquitin specific peptidase 29" Q9HBJ7 19 57119138-57131926 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 4.9" "Group enriched" "Detected in some" 8 "Collecting duct cells: 1.8;Early spermatids: 2.2;Spermatocytes: 5.1;Spermatogonia: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA076515 Enhanced NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 21: Non-specific - Transcription" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA076515: " "unprognostic (1.32e-1)" 0.1 0.0 0.9 0.0 0.5 1.8 0.0 2.1 0.6 0.0 1.0 0.1 0.1 0.2 0.0 0.2 0.1 0.2 0.5 1.0 1.0 0.1 0.1 0.2 0.4 1.9 0.9 0.3 1.3 0.0 0.0 0.2 0.8 0.1 0.1 0.6 0.7 0.0 0.3 1.4 0.0 0.0 0.8 0.2 0.4 4.9 0.8 0.0 0.3 0.0 0.1 0.3 0.0 2.0 0.0 0.2 0.2 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.3 0.9 0.2 0.0 0.0 0.3 0.0 0.5 0.2 0.3 0.4 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.2 0.0 0.3 0.0 0.1 0.3 0.2 0.0 0.2 0.0 0.6 0.5 0.2 0.1 0.1 0.1 0.3 0.2 0.3 0.4 0.3 0.1 0.0 0.0 0.4 0.1 0.3 0.1 0.2 0.0 1.3 0.3 0.3 0.2 0.2 0.1 0.2 0.1 0.1 0.1 0.2 0.1 0.1 1.1 0.3 0.1 0.6 0.1 0.2 0.9 0.5 2.1 0.6 1.0 1.0 1.9 0.9 0.8 0.8 0.8 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 USP32 "NY-REN-60, USP10" ENSG00000170832 "Ubiquitin specific peptidase 32" Q8NFA0 17 60177327-60422470 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 102.1" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 241.8;Inhibitory neurons: 113.1;Oligodendrocytes: 268.9;Rod photoreceptor cells: 136.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 59.2" "Group enriched" "Detected in all" 10 "dendritic cells: 59.2;granulocytes: 29.4" "Cell line enhanced" "Detected in all" "MCF7: 171.4" "Low region specificity" "Detected in all" HPA044365 Approved Approved "Golgi apparatus,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 77: Retina - Visual perception" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 9: Photoreceptor cells - Phototransduction" "Golgi apparatus" Cytosol "HPA044365: AB_2678914" "unprognostic (4.10e-2)" "unprognostic (3.38e-2)" "unprognostic (3.57e-2)" "prognostic unfavorable (1.50e-4)" "unprognostic (2.15e-1)" "unprognostic (4.33e-2)" "unprognostic (1.90e-3)" "unprognostic (2.33e-2)" "unprognostic (2.24e-1)" "unprognostic (3.93e-1)" "unprognostic (6.49e-2)" "unprognostic (2.78e-1)" "unprognostic (2.82e-1)" "unprognostic (1.97e-1)" "unprognostic (7.23e-2)" "unprognostic (8.35e-2)" "unprognostic (4.16e-2)" 16.1 21.8 13.6 15.0 27.8 32.1 14.1 23.2 23.6 12.4 25.2 13.0 9.5 10.3 6.8 21.7 10.7 11.8 17.4 14.3 22.8 20.2 26.6 20.7 10.5 22.2 25.0 10.0 12.5 19.2 11.9 13.2 24.8 10.8 11.4 58.8 12.9 11.2 40.8 21.0 10.5 13.7 18.1 18.5 12.2 102.1 22.3 14.4 20.6 29.2 11.6 13.1 14.7 44.4 32.6 38.2 19.0 30.8 44.8 45.3 17.2 26.4 41.9 34.5 45.8 18.6 20.0 19.4 21.5 50.0 56.1 16.3 33.1 36.9 61.5 16.8 13.9 39.7 31.8 19.5 44.1 31.7 33.6 39.6 24.6 49.9 45.2 33.5 38.6 24.4 42.9 17.1 41.1 171.4 32.3 21.3 21.7 29.6 18.8 15.8 51.6 11.5 33.1 24.5 13.1 19.1 22.9 6.0 33.8 32.1 27.4 41.3 32.6 49.7 54.9 33.1 23.5 16.2 37.4 19.6 24.6 23.6 33.4 14.5 4.3 16.5 2.0 3.7 1.4 3.0 1.4 1.7 8.5 2.2 1.0 1.9 29.4 1.3 4.6 59.2 2.6 2.1 13.6 27.8 23.2 23.6 14.3 22.8 22.2 25.0 24.8 18.1 22.3 44.4 8.0 6.4 16.4 58.8 12.5 26.9 13.3 5.8 11.4 17.3 9.2 7.6 8.2 10.0 10.1 5.5 241.8 5.1 12.6 8.5 3.9 11.3 95.0 9.0 9.9 9.8 8.3 44.2 92.3 7.5 8.4 12.6 15.8 11.6 11.4 18.5 12.5 12.0 18.5 13.5 113.1 5.6 6.1 29.7 41.3 33.3 13.1 25.1 5.4 101.2 28.0 10.4 24.7 70.4 268.9 9.6 11.4 5.7 8.3 10.3 7.4 4.6 7.0 136.4 26.3 11.9 9.1 92.7 14.9 11.2 21.9 4.9 10.9 8.5 5.5 8.2 USP4 "UNP, Unph" ENSG00000114316 "Ubiquitin specific peptidase 4" Q13107 3 49277144-49340712 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 131.8;Late spermatids: 104.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018499 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 34: Spermatids - Unknown function" "Plasma membrane, Cytosol" "HPA018499: AB_1858689" "unprognostic (2.34e-3)" "unprognostic (1.52e-1)" "unprognostic (2.22e-3)" "unprognostic (6.12e-2)" "unprognostic (3.51e-1)" "unprognostic (4.33e-2)" "unprognostic (9.42e-2)" "prognostic favorable (4.46e-5)" "unprognostic (3.54e-1)" "unprognostic (9.07e-3)" "unprognostic (2.78e-2)" "unprognostic (1.70e-3)" "prognostic favorable (4.29e-5)" "unprognostic (7.30e-2)" "unprognostic (1.00e-1)" "unprognostic (1.18e-2)" "unprognostic (1.65e-2)" 25.2 20.3 24.2 26.5 26.3 53.7 24.9 24.5 28.2 27.7 27.1 25.4 18.3 24.4 21.6 26.0 22.4 18.3 26.5 23.7 23.4 21.8 20.2 29.5 30.9 23.9 24.4 24.5 19.0 24.1 16.4 23.3 23.9 23.7 23.4 26.9 21.0 21.7 31.6 31.4 22.5 24.0 22.4 33.7 20.2 28.0 24.8 37.0 23.0 28.8 33.7 25.8 25.0 24.5 14.2 15.8 21.6 28.8 38.7 40.1 14.7 36.4 32.9 46.7 41.3 16.8 34.8 27.1 14.4 53.9 27.4 18.9 28.6 52.6 42.5 42.1 8.4 60.3 31.9 19.6 57.0 32.5 34.0 42.8 23.3 51.0 41.5 34.3 55.0 29.9 21.6 41.6 42.1 24.5 38.3 55.8 18.7 17.7 26.9 15.6 13.3 23.9 37.5 29.2 17.5 24.0 27.2 19.3 14.0 21.6 13.5 51.2 50.1 31.1 17.2 39.6 22.5 33.6 17.3 38.6 28.6 50.1 36.5 70.1 83.6 94.8 48.1 69.2 53.7 51.0 50.2 48.9 74.6 41.4 47.7 42.2 179.2 72.4 81.2 28.4 59.7 78.0 24.2 26.3 24.5 28.2 23.7 23.4 23.9 24.4 23.9 22.4 24.8 24.5 24.3 41.7 25.1 28.1 24.7 18.7 17.9 17.2 22.2 17.5 10.9 10.3 17.9 10.0 23.2 20.2 20.9 22.7 27.9 13.6 21.5 16.5 131.8 17.3 18.3 22.1 10.7 31.6 30.8 13.6 14.3 17.9 27.5 21.1 33.6 21.4 17.5 14.6 24.0 11.8 26.4 13.8 16.2 38.6 21.0 104.9 15.5 34.2 16.0 16.9 36.0 13.9 23.7 25.6 20.2 18.9 7.6 19.2 29.2 17.6 14.5 13.4 28.6 20.5 13.1 18.4 17.0 35.3 14.5 17.9 18.5 24.2 29.4 17.0 13.9 14.5 USP51 ENSG00000247746 "Ubiquitin specific peptidase 51" Q70EK9 X 55484616-55489202 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "epididymis: 51.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 23.7;Muller glia cells: 32.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SuSa: 7.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA001942 Uncertain Approved "Nucleoli fibrillar center,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 5: Muller glia cells - Visual perception" Cytosol "Nucleoli fibrillar center" "HPA001942: AB_1080536" "unprognostic (1.19e-2)" "unprognostic (4.65e-2)" "unprognostic (3.67e-2)" "unprognostic (1.02e-3)" "unprognostic (8.08e-2)" "unprognostic (3.26e-1)" "unprognostic (3.17e-3)" "unprognostic (2.07e-3)" "unprognostic (5.69e-2)" "prognostic favorable (5.70e-4)" "unprognostic (1.01e-3)" "unprognostic (1.27e-1)" "prognostic favorable (2.63e-5)" "unprognostic (2.81e-3)" "unprognostic (5.92e-2)" "unprognostic (5.85e-2)" "unprognostic (1.63e-1)" 1.4 3.1 2.5 0.9 2.7 0.5 1.7 2.8 2.8 1.9 4.2 0.8 0.4 3.1 51.7 0.6 5.5 0.8 2.1 2.2 4.2 3.7 1.2 1.5 1.1 2.2 3.1 6.5 1.1 5.6 1.4 2.4 2.4 2.4 0.8 3.1 0.8 2.5 0.4 1.1 0.7 1.9 2.5 1.8 0.8 2.3 3.8 2.4 5.3 1.1 1.2 0.9 0.7 2.5 0.0 0.6 3.9 1.1 1.9 1.0 0.0 0.6 0.3 0.7 0.9 1.2 0.5 0.0 4.6 0.8 0.8 0.2 1.0 0.4 1.2 1.3 0.0 1.0 0.2 0.0 0.8 2.5 0.2 3.9 0.0 0.4 0.0 0.3 0.2 3.0 3.1 3.0 0.6 2.6 2.4 1.3 4.8 0.0 0.2 3.4 0.7 1.5 0.9 0.1 0.0 0.7 1.1 0.1 3.7 7.0 0.9 1.3 0.2 1.5 2.1 0.4 0.1 4.7 2.0 0.9 1.0 1.4 1.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.5 2.7 2.8 2.8 2.2 4.2 2.2 3.1 2.4 2.5 3.8 2.5 5.1 3.2 5.5 3.3 2.6 0.9 2.2 0.9 2.2 23.7 3.8 7.4 6.9 1.5 2.0 3.7 6.2 4.3 1.2 0.2 9.8 1.5 0.3 9.0 9.2 6.0 3.6 5.0 2.7 0.0 2.2 8.1 0.0 2.1 1.3 7.9 6.4 0.7 7.6 6.7 5.0 0.5 0.0 5.6 2.5 1.0 4.1 4.7 5.4 1.9 0.3 32.9 3.1 3.5 3.7 0.2 0.3 8.2 1.0 1.0 0.0 13.1 11.2 16.4 0.0 7.1 5.0 11.4 12.5 1.0 0.4 2.7 3.1 13.0 0.4 0.5 UTS2B "U2B, URP, UTS2D" ENSG00000188958 "Urotensin 2B" Q765I0 3 191267168-191330536 "Predicted secreted proteins" Hormone "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "retina: 14.9" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;B-cells: 2.6;Early spermatids: 8.3;Late spermatids: 2.3;Oligodendrocyte precursor cells: 3.0;Spermatocytes: 2.6;Spermatogonia: 2.1" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 4 "memory B-cell: 2.8;naive B-cell: 1.8" "Lineage enriched" "Detected in single" 5 "B-cells: 2.8" "Cell line enhanced" "Detected in some" "PC-3: 3.3" "Region enriched" "Detected in some" 9 "pons and medulla: 11.3" "Region enriched" "Detected in single" 46 "spinal cord: 6.0" HPA026992 Uncertain "Secreted - unknown location" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 77: Retina - Visual perception" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA026992: AB_1858703" "unprognostic (1.73e-2)" "unprognostic (4.38e-2)" "unprognostic (1.22e-1)" "unprognostic (3.41e-1)" "unprognostic (1.92e-1)" "unprognostic (2.17e-2)" "unprognostic (2.77e-2)" "unprognostic (2.14e-2)" "unprognostic (3.09e-1)" "unprognostic (2.63e-2)" "unprognostic (3.39e-2)" "unprognostic (2.63e-1)" "unprognostic (1.11e-1)" "unprognostic (7.58e-2)" "unprognostic (2.08e-1)" "unprognostic (1.29e-1)" "unprognostic (3.10e-2)" 1.0 1.2 0.8 0.8 0.5 0.5 1.2 4.1 1.4 0.2 0.0 0.5 5.3 0.7 0.5 0.7 1.0 1.2 0.7 0.7 0.5 0.6 3.2 0.5 1.0 0.7 0.4 1.0 0.5 0.2 0.0 0.4 1.1 0.6 0.4 14.9 0.6 0.2 0.5 1.1 3.2 0.5 0.1 0.6 1.6 2.3 0.6 0.1 0.5 0.0 0.3 0.4 0.1 0.9 0.4 1.0 1.3 0.6 0.3 1.6 0.4 1.0 0.5 0.3 0.2 0.7 0.5 0.7 0.5 0.4 2.6 0.5 0.4 0.0 1.6 0.6 0.5 0.6 1.4 2.9 0.3 0.8 0.4 0.6 0.2 0.2 0.3 0.9 0.3 0.6 0.4 0.6 0.5 0.6 0.2 0.5 0.7 1.3 3.3 0.9 1.5 0.2 0.2 1.6 0.7 0.5 0.6 0.7 0.4 0.5 0.5 0.5 1.4 0.7 0.4 1.3 0.4 1.1 0.6 0.6 0.9 0.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.8 0.5 4.1 1.4 0.7 0.5 0.7 0.4 1.1 0.1 0.6 0.9 0.2 3.2 1.1 0.7 2.6 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 8.3 1.4 0.4 0.1 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.1 0.0 0.4 0.0 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.0 2.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.0 0.2 0.1 0.0 0.7 1.6 0.0 0.2 0.1 1.5 0.0 0.0 0.1 0.2 2.6 2.1 0.0 0.3 0.3 0.0 0.1 0.0 0.1 UXS1 "FLJ23591, SDR6E1, UGD" ENSG00000115652 "UDP-glucuronate decarboxylase 1" Q8NBZ7 2 106093308-106194301 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPTEC TERT1: 323.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008825 Uncertain "Intracellular and membrane" NA NA 24000 "Cluster 20: T-cells - T-cell receptor" "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA008825: AB_1858708" "unprognostic (4.08e-1)" "unprognostic (1.52e-1)" "unprognostic (1.99e-1)" "unprognostic (3.63e-2)" "unprognostic (3.92e-2)" "prognostic unfavorable (5.45e-4)" "prognostic unfavorable (1.38e-4)" "unprognostic (3.20e-3)" "unprognostic (2.07e-1)" "prognostic favorable (7.94e-4)" "unprognostic (3.95e-2)" "unprognostic (1.40e-2)" "unprognostic (8.46e-2)" "unprognostic (3.96e-2)" "unprognostic (6.18e-2)" "unprognostic (1.86e-2)" "unprognostic (5.32e-2)" 16.3 17.6 20.4 25.0 18.7 40.4 15.3 30.4 29.3 19.6 20.6 21.7 15.5 24.3 33.1 24.1 29.2 19.6 29.3 25.9 20.3 60.0 15.7 46.0 27.9 15.0 23.0 24.4 15.8 37.3 16.3 54.6 19.3 23.2 24.0 10.5 14.6 25.9 31.9 14.0 14.3 21.4 18.5 25.0 26.2 31.9 31.0 22.2 30.0 28.6 30.4 29.5 18.3 23.7 66.5 48.8 50.9 39.0 88.4 65.2 110.2 71.4 66.9 49.9 61.5 96.9 110.4 12.0 87.0 74.1 111.2 32.8 22.6 58.2 54.5 64.2 40.5 37.0 21.4 110.6 34.9 30.5 39.0 42.8 63.8 50.3 33.5 57.5 52.5 22.8 22.1 28.5 103.6 46.8 34.3 66.8 60.1 64.2 65.4 70.3 38.6 34.3 323.0 60.9 16.7 19.0 51.5 45.7 44.3 67.7 17.0 93.7 48.0 55.1 58.5 45.4 45.4 34.4 51.4 17.9 55.0 70.1 103.8 11.3 24.7 28.5 23.1 20.8 25.7 15.3 64.3 41.4 19.1 30.5 68.8 49.1 6.1 37.5 16.0 13.5 130.4 44.3 20.4 18.7 30.4 29.3 25.9 20.3 15.0 23.0 19.3 18.5 31.0 23.7 15.4 89.8 88.8 18.9 22.1 16.8 26.8 117.3 14.8 9.9 11.6 10.5 18.7 17.2 61.6 86.5 4.2 71.2 17.7 20.5 50.9 46.9 80.2 41.5 19.3 25.5 6.6 12.0 49.8 25.0 74.1 34.2 16.8 40.6 29.8 13.1 10.8 15.0 33.2 8.4 37.5 15.6 34.6 20.1 12.5 18.5 15.2 33.9 14.2 33.7 56.2 10.8 18.6 24.1 11.7 30.4 16.2 12.8 10.2 35.7 9.6 17.5 38.8 7.9 19.7 19.0 35.1 17.0 81.6 22.6 13.2 24.6 33.7 51.6 18.0 19.8 VARS1 "VARS, VARS2" ENSG00000204394 "Valyl-tRNA synthetase 1" P26640 6 31777518-31795752 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 10.1;Cytotrophoblasts: 23.2;Extravillous trophoblasts: 48.3;Hofbauer cells: 30.7;Syncytiotrophoblasts: 16.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "U-266/84: 140.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046710 Approved Enhanced Cytosol NA NA 110000 "Cluster 39: Non-specific - mRNA processing" "Cluster 71: Testis - DNA repair" "Cluster 16: U-266 - Nucleosome" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA046710: AB_2679765" "unprognostic (1.86e-2)" "prognostic unfavorable (7.25e-4)" "unprognostic (2.19e-1)" "unprognostic (2.07e-1)" "unprognostic (2.49e-2)" "unprognostic (3.43e-2)" "prognostic unfavorable (1.86e-4)" "prognostic unfavorable (6.90e-4)" "unprognostic (3.20e-1)" "unprognostic (2.76e-1)" "unprognostic (4.72e-1)" "unprognostic (1.28e-1)" "unprognostic (1.09e-2)" "unprognostic (1.98e-1)" "unprognostic (1.69e-1)" "unprognostic (3.85e-2)" "unprognostic (2.59e-1)" 22.2 24.6 2.0 6.6 1.6 3.2 21.9 0.4 2.4 20.1 0.0 21.0 5.6 29.4 0.9 32.5 22.1 1.1 20.0 0.7 2.3 19.2 29.3 19.8 3.0 2.4 1.9 19.7 37.3 2.5 33.6 2.2 2.2 17.6 1.7 1.3 20.6 1.2 58.2 34.3 21.9 3.5 0.8 30.0 23.3 63.6 2.6 3.0 18.5 3.1 2.8 23.5 20.7 1.5 36.2 11.6 12.4 36.9 9.1 8.5 84.0 52.2 10.8 25.2 13.3 11.5 9.9 58.3 60.2 18.4 18.9 22.0 33.5 32.4 8.8 46.0 74.0 31.7 18.4 21.3 18.3 75.7 60.6 12.5 8.2 14.8 16.5 6.2 13.5 22.9 92.2 48.8 12.7 13.2 51.0 16.2 35.0 11.9 32.5 55.5 20.5 132.7 13.0 12.4 42.1 26.2 12.0 31.0 19.5 5.8 23.2 34.0 31.2 24.2 37.8 28.2 72.5 87.9 140.4 44.1 14.6 31.1 29.0 0.0 0.3 0.1 0.2 0.3 0.3 0.5 0.3 0.3 0.5 0.3 0.3 0.1 0.1 0.5 0.3 0.6 0.1 0.5 2.0 1.6 0.4 2.4 0.7 2.3 2.4 1.9 2.2 0.8 2.6 1.5 4.2 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.1 0.0 0.0 0.0 0.0 23.2 1.9 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 48.3 3.6 0.0 0.0 0.0 0.0 0.0 0.0 30.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 16.6 0.4 0.0 0.0 0.0 VCAN "CSPG2, PG-M" ENSG00000038427 Versican P13611 5 83471618-83582303 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 975.7;Granulosa cells: 1131.8;Kupffer cells: 547.3;Macrophages: 605.6;monocytes: 948.1;Oligodendrocyte precursor cells: 1644.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 240.0;myeloid DC: 88.9" "Group enriched" "Detected in many" 20 "dendritic cells: 88.9;monocytes: 240.0" "Cell line enhanced" "Detected in many" "AF22: 300.5;HSkMC: 199.5;hTERT-RPE1: 959.0;RPTEC TERT1: 381.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004726, CAB008979" Supported Approved Vesicles "Secreted to blood" NA NA 12000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "CAB008979: , HPA004726: AB_1080561" "unprognostic (7.90e-2)" "unprognostic (9.03e-3)" "unprognostic (7.09e-2)" "unprognostic (6.06e-3)" "unprognostic (1.87e-1)" "unprognostic (4.49e-2)" "unprognostic (1.23e-2)" "unprognostic (1.17e-2)" "prognostic unfavorable (7.59e-4)" "unprognostic (4.36e-3)" "unprognostic (2.68e-3)" "unprognostic (2.05e-1)" "prognostic unfavorable (5.17e-4)" "prognostic unfavorable (1.41e-4)" "unprognostic (1.15e-1)" "unprognostic (4.44e-2)" "unprognostic (5.30e-3)" 42.0 23.9 18.6 74.9 20.8 32.6 15.6 24.2 23.0 29.4 5.2 11.3 3.8 17.8 1.8 3.8 8.6 30.5 45.0 25.7 27.8 6.5 2.7 34.4 2.3 36.1 19.3 2.1 3.1 2.4 2.1 73.5 31.3 6.8 10.7 0.2 7.6 4.2 3.9 11.2 5.7 48.0 28.9 13.9 7.7 4.8 44.9 2.7 6.6 6.8 1.9 48.3 7.2 42.7 0.2 5.6 300.5 0.1 119.8 81.5 0.1 2.3 6.2 2.1 1.5 3.1 0.2 0.0 45.2 111.5 3.9 0.0 0.4 0.4 1.7 0.1 9.8 2.1 0.0 2.3 5.5 0.1 0.0 199.5 0.1 127.6 1.2 959.0 0.1 0.0 0.0 0.1 64.6 0.0 0.5 0.0 51.1 0.0 10.3 0.0 63.0 0.1 381.0 0.0 3.6 15.5 0.0 0.0 0.2 33.2 0.2 0.5 116.5 90.6 0.5 168.3 179.0 0.0 0.1 0.2 41.8 0.1 16.4 8.3 240.0 0.5 0.5 31.3 0.3 0.2 0.1 0.1 88.9 0.1 0.1 0.0 3.9 0.5 3.5 1.7 0.0 94.0 18.6 20.8 24.2 23.0 25.7 27.8 36.1 19.3 31.3 28.9 44.9 42.7 23.4 19.2 19.8 128.9 5.5 38.6 10.6 14.9 1.2 0.0 1.8 1.9 8.2 44.3 17.5 25.8 0.0 5.9 7.4 0.0 0.0 1.9 3.0 64.4 975.7 29.9 0.0 5.2 1.5 0.7 7.0 348.1 3.6 241.3 12.6 1131.8 16.8 3.6 25.6 0.0 30.7 0.2 0.0 547.3 83.1 2.5 18.6 605.6 44.4 20.6 948.1 0.0 13.4 1644.7 1.5 32.3 1.1 117.8 2.5 2.5 0.0 1.8 16.2 0.0 0.0 11.0 80.6 0.9 1.2 1.1 28.7 11.5 12.7 1.6 0.3 0.9 VIL1 "D2S1471, VIL" ENSG00000127831 "Villin 1" P09327 2 218419121-218453295 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" Apoptosis "Actin capping, Actin-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "intestine: 436.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 243.8;Enteroendocrine cells: 113.6;Intestinal goblet cells: 143.6;Paneth cells: 216.2;Proximal enterocytes: 558.5;Undifferentiated cells: 161.8" "Group enriched" "Detected in many" 4 "colorectal cancer: 56.4;stomach cancer: 23.5" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 4 "neutrophil: 1.3" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.3" "Group enriched" "Detected in some" 97 "CACO-2: 762.5;Hep G2: 365.3;OE19: 321.9" "Low region specificity" "Detected in single" "Not detected" "Not detected" "CAB002452, HPA006884, HPA006885" Enhanced Enhanced "Plasma membrane" NA NA 6800 "Cluster 9: Neutrophils - Innate immune response" "Cluster 9: Intestine - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "CAB002452: AB_564052, HPA006884: AB_1080566, HPA006885: AB_1080564" "unprognostic (1.28e-1)" "unprognostic (1.91e-2)" "unprognostic (1.61e-2)" "unprognostic (1.09e-1)" "unprognostic (1.83e-1)" "unprognostic (3.36e-1)" "unprognostic (3.03e-1)" "unprognostic (5.90e-2)" "unprognostic (2.44e-2)" "unprognostic (7.06e-2)" "unprognostic (4.14e-1)" "unprognostic (1.03e-1)" "unprognostic (2.25e-3)" "unprognostic (3.90e-1)" "unprognostic (2.58e-1)" "unprognostic (4.79e-2)" "unprognostic (4.65e-2)" 0.6 1.1 0.0 10.3 0.1 0.3 0.8 0.3 0.2 0.7 0.0 175.9 395.0 0.5 0.0 0.9 0.7 28.1 1.0 0.0 0.0 25.9 31.4 0.7 0.3 0.0 0.0 1.1 29.4 0.0 1.4 0.3 0.0 1.0 184.0 0.0 0.6 0.4 0.4 1.1 436.3 8.1 0.0 1.2 6.9 2.0 0.0 0.0 0.6 0.0 0.0 0.8 0.9 0.1 0.0 1.5 0.0 0.1 0.0 0.1 1.0 0.0 0.0 0.0 0.0 762.5 0.5 0.1 5.0 0.0 0.5 0.1 0.3 0.0 0.0 0.0 0.4 0.0 0.3 365.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.4 0.1 0.0 0.1 0.0 1.7 0.8 321.9 0.0 0.0 0.0 1.4 0.0 0.2 0.3 0.7 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.2 0.0 4.0 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 1.3 0.8 0.4 0.1 0.0 1.8 0.3 0.6 0.5 24.3 0.1 0.0 2.1 0.3 0.8 243.8 3.9 12.3 1.9 1.3 0.9 0.4 113.6 3.2 0.7 42.9 0.2 0.8 6.6 1.6 8.9 0.3 0.7 32.6 0.1 1.7 0.5 143.6 0.0 2.2 1.5 0.5 0.0 5.1 0.0 0.0 0.2 0.5 0.0 0.0 0.3 10.9 216.2 0.0 0.3 0.9 558.5 35.1 0.0 1.2 0.0 1.7 0.7 0.8 0.8 0.6 0.9 0.3 1.5 0.0 161.8 0.3 VIPAS39 "C14orf133, hSPE-39, SPE-39, SPE39, VIPAR, VPS16B" ENSG00000151445 "VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog" Q9H9C1 14 77426675-77457952 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Protein transport, Spermatogenesis, Transcription, Transcription regulation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003589, HPA003593" Approved NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 47: Cytotrophoblasts - Unknown function" "HPA003589: AB_10599707, HPA003593: AB_10601879" "unprognostic (1.30e-1)" "unprognostic (7.56e-2)" "unprognostic (3.41e-2)" "unprognostic (1.04e-1)" "unprognostic (5.79e-3)" "unprognostic (5.76e-2)" "prognostic unfavorable (1.06e-6)" "unprognostic (2.53e-2)" "unprognostic (1.67e-1)" "unprognostic (5.77e-2)" "unprognostic (1.57e-1)" "unprognostic (1.36e-1)" "unprognostic (1.56e-3)" "unprognostic (5.31e-3)" "unprognostic (3.48e-1)" "unprognostic (5.91e-2)" "unprognostic (1.09e-2)" 12.4 11.8 15.3 9.4 16.0 9.1 12.2 15.4 17.9 12.1 15.6 14.3 10.1 12.1 14.7 13.2 10.8 9.1 14.8 15.7 15.6 11.2 13.6 9.9 12.4 15.2 15.3 18.5 11.9 14.6 13.4 15.5 15.6 11.8 12.7 14.4 10.0 13.7 13.7 13.7 11.1 14.6 15.6 13.2 11.6 15.9 15.9 16.5 11.7 15.0 14.7 13.9 11.6 17.7 10.6 17.8 18.3 26.6 32.5 26.5 18.3 17.5 16.1 20.8 20.2 11.9 24.7 18.4 15.1 14.3 10.8 20.4 17.0 15.5 24.9 15.8 5.8 13.7 10.7 14.7 26.3 8.6 23.2 25.4 24.2 17.8 24.2 27.7 36.3 25.5 10.9 17.4 19.9 25.1 17.7 18.4 16.5 31.0 19.3 17.6 23.0 12.7 20.9 15.3 13.0 15.0 22.7 16.7 20.2 21.7 39.1 18.1 25.9 14.1 12.5 15.5 9.8 14.8 15.1 14.6 15.3 15.9 17.0 1.8 9.4 17.6 5.0 15.6 6.5 4.8 6.5 5.6 10.8 5.6 5.7 5.6 7.8 13.0 20.3 5.5 7.8 6.1 15.3 16.0 15.4 17.9 15.7 15.6 15.2 15.3 15.6 15.6 15.9 17.7 6.0 3.2 1.5 16.0 6.3 3.2 3.0 4.7 2.8 8.5 5.3 5.3 9.0 4.3 3.4 9.2 20.9 20.7 6.3 7.2 7.9 9.3 5.7 4.0 7.4 6.8 5.4 11.2 14.6 6.3 16.6 8.2 5.1 6.2 2.5 12.2 8.2 6.6 13.3 10.1 14.4 5.4 2.0 17.6 3.8 3.8 11.5 8.3 0.0 13.1 17.6 7.4 9.2 15.1 17.2 9.1 9.4 15.4 4.0 2.5 10.7 5.8 3.6 13.3 6.6 5.5 6.8 11.0 9.2 6.3 4.3 19.2 6.3 15.5 7.2 2.8 VNN2 "FOAP-4, GPI-80" ENSG00000112303 "Vanin 2" O95498 6 132743870-132763459 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 31.6;lymphoid tissue: 56.6" "Cell type enhanced" "Detected in many" "Ductal cells: 63.6;Ionocytes: 22.4;Macrophages: 41.1;monocytes: 57.5;Respiratory ciliated cells: 25.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 7 "neutrophil: 477.4" "Lineage enriched" "Detected in all" 7 "granulocytes: 477.4" "Cell line enriched" "Detected in some" 7 "Daudi: 59.7" "Low region specificity" "Detected in some" NA NA 240000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "unprognostic (2.13e-1)" "unprognostic (1.15e-1)" "unprognostic (9.60e-3)" "unprognostic (5.71e-2)" "unprognostic (2.14e-1)" "unprognostic (5.61e-3)" "unprognostic (1.98e-3)" "unprognostic (4.38e-1)" "unprognostic (3.07e-1)" "unprognostic (3.46e-1)" "unprognostic (2.84e-1)" "unprognostic (8.30e-2)" "prognostic unfavorable (2.72e-7)" "unprognostic (1.62e-1)" "unprognostic (8.17e-2)" "unprognostic (2.01e-1)" "unprognostic (5.45e-2)" 21.7 2.7 0.6 23.9 0.9 31.6 1.3 0.7 2.8 4.3 1.4 3.8 2.4 1.3 0.4 4.1 5.3 22.5 2.3 0.5 0.7 2.4 10.1 22.5 39.0 1.5 1.0 1.5 4.3 0.7 0.9 20.7 1.7 1.8 3.0 0.1 1.5 0.9 0.6 0.3 4.6 6.3 0.8 56.6 7.3 0.6 1.0 11.7 1.2 7.9 42.0 17.8 1.2 1.0 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 59.7 1.1 0.0 1.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.9 0.0 0.0 1.3 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.6 0.0 1.1 1.4 0.0 0.0 11.6 65.2 0.3 24.6 14.5 10.3 40.3 8.4 29.0 14.1 32.2 27.0 39.4 477.4 36.1 9.9 2.6 6.1 40.4 0.6 0.9 0.7 2.8 0.5 0.7 1.5 1.0 1.7 0.8 1.0 1.0 0.2 0.0 6.7 0.0 11.0 0.0 0.5 4.3 0.0 0.0 0.2 0.0 1.5 7.2 11.8 0.0 0.0 0.8 10.9 0.1 0.0 63.6 0.0 0.3 0.0 1.4 0.0 1.3 0.2 0.4 0.2 1.9 13.3 0.2 5.1 0.1 3.3 1.0 13.9 0.0 0.0 0.0 22.4 18.6 1.0 0.0 0.0 41.1 0.0 1.9 57.5 0.3 20.6 0.0 0.1 3.6 0.0 0.0 2.7 8.0 0.0 0.6 25.4 0.1 6.6 2.5 1.2 0.1 0.0 0.1 0.0 1.4 10.9 6.5 0.2 14.5 VPS33A ENSG00000139719 "VPS33A core subunit of CORVET and HOPS complexes" Q96AX1 12 122229564-122266494 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Autophagy, Protein transport, Transport" "Disease variant, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA038701 Approved Nucleoplasm NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 16: U-266 - Nucleosome" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Nucleoplasm "HPA038701: AB_10673473" "unprognostic (3.98e-2)" "unprognostic (2.90e-2)" "unprognostic (4.07e-2)" "unprognostic (4.61e-3)" "unprognostic (2.00e-1)" "unprognostic (2.14e-1)" "prognostic unfavorable (9.11e-5)" "unprognostic (2.17e-1)" "unprognostic (1.47e-1)" "unprognostic (2.40e-1)" "unprognostic (3.44e-3)" "unprognostic (1.25e-1)" "prognostic unfavorable (5.29e-4)" "unprognostic (4.63e-2)" "unprognostic (7.65e-2)" "prognostic favorable (2.41e-4)" "unprognostic (1.09e-2)" 4.9 6.8 7.1 6.0 7.5 7.0 6.0 8.4 9.3 4.4 7.0 6.8 5.7 5.1 7.6 5.0 5.9 4.1 4.8 7.3 8.2 4.5 6.0 5.3 8.1 7.3 7.1 5.9 5.4 6.1 9.2 8.5 7.8 4.9 5.5 10.5 4.5 4.9 9.0 7.0 5.9 6.5 6.7 6.9 5.6 8.1 7.6 9.6 4.3 6.1 6.8 5.4 4.2 8.9 13.2 17.1 17.3 6.9 13.3 10.2 20.0 11.9 12.9 20.4 12.7 28.2 6.4 14.6 9.8 8.0 14.2 11.1 31.6 12.6 17.5 19.9 16.9 15.1 11.5 24.8 17.0 20.6 15.6 11.4 10.4 14.5 11.5 16.8 13.5 16.0 34.3 7.3 13.3 14.7 10.1 21.2 25.2 10.8 18.5 17.2 16.0 17.5 8.7 13.6 12.6 19.0 25.0 7.4 22.7 17.8 31.6 13.8 8.8 9.2 14.5 17.4 11.0 23.1 54.2 23.4 14.5 13.1 12.8 29.6 11.5 19.0 11.3 12.6 10.3 12.0 12.7 12.2 12.1 8.9 9.0 10.5 9.4 13.6 15.2 7.6 18.6 10.9 7.1 7.5 8.4 9.3 7.3 8.2 7.3 7.1 7.8 6.7 7.6 8.9 5.7 9.6 3.9 6.8 14.0 3.2 4.0 8.1 3.4 18.1 5.4 4.8 7.3 5.7 6.8 7.3 10.4 21.7 11.3 10.1 3.9 15.0 23.0 5.9 6.5 6.6 18.0 12.2 13.8 12.6 21.4 7.0 8.2 5.2 14.5 10.2 9.7 10.2 21.2 3.3 13.9 7.7 6.1 11.5 5.3 13.1 8.1 13.4 3.6 10.3 20.7 12.1 15.5 8.5 15.3 15.0 8.8 11.3 12.6 2.5 8.5 11.3 12.6 17.7 19.7 5.4 6.2 38.8 31.4 7.0 3.0 21.6 13.4 10.0 8.2 2.9 VPS39 "KIAA0770, VAM6" ENSG00000166887 "VPS39 subunit of HOPS complex" Q96JC1 15 42158701-42208307 "Plasma proteins, Predicted intracellular proteins" "Autophagy, Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 57.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 43: Cardiomyocytes - Nuclear processes" "unprognostic (4.39e-1)" "unprognostic (2.52e-1)" "unprognostic (1.28e-2)" "prognostic favorable (3.21e-7)" "unprognostic (9.85e-2)" "unprognostic (2.14e-2)" "unprognostic (3.40e-3)" "unprognostic (2.59e-2)" "unprognostic (2.71e-1)" "unprognostic (2.81e-2)" "unprognostic (1.01e-2)" "unprognostic (6.59e-2)" "unprognostic (1.85e-3)" "unprognostic (1.53e-1)" "unprognostic (4.51e-1)" "unprognostic (3.28e-2)" "unprognostic (5.04e-2)" 24.2 24.9 16.0 18.5 17.0 23.8 19.0 13.7 19.8 23.5 12.4 22.1 18.5 23.8 24.7 20.4 25.3 20.6 28.3 17.8 17.5 22.3 13.0 24.5 23.0 15.8 16.7 21.1 26.5 43.7 19.8 22.0 16.6 24.1 19.8 21.3 22.0 26.1 36.5 29.4 21.4 27.3 15.9 22.9 20.9 20.9 19.0 31.6 26.6 34.7 26.2 20.4 17.5 15.6 15.6 21.6 30.7 35.0 55.2 52.9 19.5 27.3 49.1 32.5 34.1 18.5 13.2 13.9 27.0 50.1 34.0 36.0 24.1 27.4 29.8 43.6 13.7 33.7 34.6 17.4 38.1 30.8 25.0 46.6 38.8 30.5 31.4 38.0 34.3 38.2 25.2 37.4 36.4 13.9 23.7 17.2 19.1 34.9 18.4 17.9 28.6 22.0 23.7 36.0 27.2 39.7 22.5 21.5 14.4 31.5 34.5 39.7 37.6 28.0 11.8 33.9 20.3 31.7 45.3 20.2 34.2 27.6 23.2 38.5 14.7 18.2 14.9 16.4 15.1 15.2 13.3 16.1 15.6 11.9 13.4 12.7 16.6 20.8 15.6 6.7 13.1 18.5 16.0 17.0 13.7 19.8 17.8 17.5 15.8 16.7 16.6 15.9 19.0 15.6 14.4 22.4 43.2 27.1 15.7 3.6 3.3 5.6 10.8 11.7 14.0 13.2 57.0 15.7 11.4 9.2 14.6 10.3 12.6 17.5 1.9 7.3 11.4 16.0 16.8 14.4 9.6 16.6 31.2 8.0 7.8 13.7 24.5 15.7 9.5 15.3 9.7 11.8 12.2 11.8 32.2 11.9 10.2 16.9 4.4 21.6 12.2 14.7 3.6 30.9 16.0 13.5 8.2 29.1 34.4 10.2 11.4 13.9 28.7 5.8 14.7 6.2 13.3 11.6 0.0 8.9 10.7 5.2 4.5 12.6 7.0 13.4 13.7 10.5 10.0 4.5 VSIG10L ENSG00000186806 "V-set and immunoglobulin domain containing 10 like" Q86VR7 19 51331536-51342124 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 20.3;esophagus: 62.3;salivary gland: 23.5;vagina: 22.3" "Cell type enhanced" "Detected in many" "Horizontal cells: 10.1;Melanocytes: 5.4;Sertoli cells: 6.6;Squamous epithelial cells: 6.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Hep G2: 4.7;OE19: 11.0;T-47d: 8.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA060453, HPA066745" Uncertain Approved Nucleoplasm NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA060453: AB_2684280, HPA066745: AB_2685712" "unprognostic (1.70e-2)" "unprognostic (1.95e-2)" "unprognostic (1.30e-2)" "unprognostic (2.98e-3)" "unprognostic (1.08e-2)" "unprognostic (3.96e-2)" "prognostic unfavorable (8.75e-4)" "unprognostic (2.40e-3)" "unprognostic (2.78e-1)" "unprognostic (9.87e-2)" "unprognostic (2.62e-2)" "unprognostic (1.87e-1)" "unprognostic (2.90e-4)" "unprognostic (1.42e-2)" "unprognostic (8.51e-2)" "unprognostic (7.74e-2)" "unprognostic (5.19e-3)" 0.2 0.1 0.1 0.0 0.4 0.1 0.8 0.8 0.5 20.3 0.0 0.1 0.0 0.0 0.0 62.3 0.1 0.3 0.1 0.1 0.7 0.1 0.7 0.1 0.1 0.5 1.0 0.2 0.0 0.0 0.1 0.0 0.8 1.2 0.0 0.0 23.5 0.1 0.1 10.6 0.2 0.0 0.1 0.1 0.1 0.3 0.6 0.1 0.1 0.0 6.3 0.2 22.3 0.7 0.0 0.9 0.0 0.3 0.4 0.1 0.2 0.1 0.0 0.0 0.1 0.3 0.7 0.6 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.5 0.5 0.1 0.2 4.7 0.0 0.0 0.8 0.0 0.5 0.1 0.0 0.0 0.0 0.2 0.4 1.3 0.0 0.4 0.0 0.1 0.6 11.0 0.4 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.1 8.4 0.0 0.0 0.0 0.1 0.7 0.0 1.1 0.7 0.1 0.5 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.8 0.5 0.1 0.7 0.5 1.0 0.8 0.1 0.6 0.7 1.2 0.0 0.5 1.3 0.8 0.6 1.1 0.6 1.8 1.6 2.2 1.8 0.9 0.0 0.1 0.0 0.0 0.4 0.2 0.9 0.0 1.1 0.2 0.0 0.3 0.5 1.2 0.0 0.6 0.0 0.9 1.6 1.1 0.2 1.3 1.0 1.4 1.2 4.5 10.1 1.0 0.5 0.0 3.2 0.9 0.7 2.1 2.4 5.4 1.0 1.1 1.4 0.0 0.0 0.9 0.4 1.3 4.1 0.1 1.0 1.6 0.9 0.0 0.6 6.6 1.5 1.2 0.5 2.6 6.1 0.4 0.5 0.4 2.2 0.7 0.7 VWA8 KIAA0564 ENSG00000102763 "Von Willebrand factor A domain containing 8" A3KMH1 13 41566835-41961120 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 161.9;Excitatory neurons: 183.9;Inhibitory neurons: 252.6;Oligodendrocyte precursor cells: 151.3;Oligodendrocytes: 146.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039075, HPA045478" Uncertain Approved "Vesicles,Lipid droplets" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Vesicles, Lipid droplets" "HPA039075: AB_2676334, HPA045478: AB_2679341" "unprognostic (9.93e-2)" "unprognostic (4.12e-2)" "unprognostic (2.11e-1)" "unprognostic (2.57e-3)" "unprognostic (4.14e-2)" "unprognostic (1.50e-2)" "prognostic favorable (8.56e-4)" "unprognostic (1.03e-1)" "unprognostic (3.01e-2)" "unprognostic (3.31e-3)" "unprognostic (5.35e-2)" "unprognostic (2.44e-1)" "prognostic favorable (6.38e-14)" "unprognostic (1.84e-2)" "unprognostic (3.07e-2)" "unprognostic (2.12e-1)" "unprognostic (3.26e-1)" 8.0 7.8 5.1 3.7 6.8 5.7 8.7 9.5 5.6 9.2 14.3 6.8 7.1 7.2 5.5 5.7 6.4 5.3 13.7 2.9 5.0 17.6 21.6 4.9 4.5 5.5 6.4 6.3 7.3 14.6 3.8 5.0 6.2 6.1 7.5 15.1 7.7 5.8 29.3 4.1 5.4 6.0 4.0 3.7 6.6 4.1 7.9 7.7 7.1 35.1 4.4 6.2 3.8 5.1 5.2 7.6 7.6 10.5 7.0 10.2 7.1 8.2 12.0 7.3 5.8 10.0 8.2 13.8 5.4 7.2 5.9 18.3 7.1 20.0 9.1 15.6 12.3 13.1 7.0 12.7 7.5 17.3 1.7 12.0 12.2 7.0 16.7 9.9 7.4 10.8 12.7 9.6 6.5 7.0 9.8 8.9 11.4 13.6 7.0 0.1 4.8 14.5 19.7 18.8 4.7 10.0 10.2 15.9 11.4 8.3 6.6 13.2 6.6 5.5 5.8 7.1 7.8 9.7 9.9 21.4 6.1 8.2 7.3 0.6 0.4 0.0 1.1 0.4 1.6 0.7 0.6 1.0 0.9 1.0 0.8 1.2 0.2 1.6 0.6 0.5 0.4 0.8 5.1 6.8 9.5 5.6 2.9 5.0 5.5 6.4 6.2 4.0 7.9 5.1 7.5 16.0 2.6 161.9 9.2 4.0 16.5 8.2 9.6 10.7 13.1 5.7 45.5 11.5 10.4 5.5 35.5 7.6 7.3 7.5 1.9 3.7 35.4 10.1 7.6 5.3 3.0 12.0 183.9 1.6 2.1 6.2 15.8 14.4 0.0 5.8 2.2 16.5 3.9 3.3 252.6 7.8 4.1 3.8 4.0 14.2 5.9 11.5 5.4 69.3 4.1 4.9 4.1 151.3 146.1 4.0 9.3 5.3 18.2 16.0 9.4 8.2 6.7 42.6 0.0 7.6 8.9 5.5 4.8 12.5 2.8 2.9 10.4 8.5 9.4 11.9 WBP2NL "FLJ26145, GRAMD7, MGC26816, PAWP" ENSG00000183066 "WBP2 N-terminal like" Q6ICG8 22 41998725-42058456 "Predicted intracellular proteins" Meiosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "testis: 17.8" "Group enriched" "Detected in many" 10 "Early spermatids: 254.5;Late spermatids: 807.7" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA048557 Enhanced Approved Cytosol NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "HPA048557: AB_2680440" "unprognostic (1.90e-2)" "unprognostic (2.25e-4)" "unprognostic (2.77e-3)" "unprognostic (6.12e-2)" "unprognostic (6.48e-2)" "unprognostic (1.43e-1)" "unprognostic (1.41e-2)" "unprognostic (1.04e-2)" "unprognostic (1.38e-1)" "unprognostic (2.96e-1)" "unprognostic (9.84e-4)" "unprognostic (3.31e-2)" "unprognostic (4.19e-2)" "unprognostic (1.79e-1)" "unprognostic (2.06e-1)" "unprognostic (2.85e-3)" "unprognostic (9.36e-5)" 0.2 0.1 0.6 0.0 0.6 0.0 0.7 0.6 0.9 0.2 0.0 0.2 0.1 0.2 1.2 0.1 0.5 0.2 0.0 0.6 0.6 0.3 0.1 0.3 0.2 1.0 0.7 0.6 0.7 0.4 0.3 0.1 1.0 0.3 0.1 0.7 0.5 0.3 0.1 0.4 0.2 0.1 0.8 0.2 0.3 17.8 0.5 0.1 0.6 0.1 0.1 0.1 0.2 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.6 0.6 0.6 0.9 0.6 0.6 1.0 0.7 1.0 0.8 0.5 1.4 0.3 0.0 2.8 50.6 4.3 0.4 2.1 1.0 2.8 16.4 1.8 2.4 0.7 2.8 3.7 0.0 20.9 2.2 0.6 1.7 3.9 0.9 254.5 0.9 1.5 1.3 4.8 0.4 16.0 1.3 1.0 0.9 1.5 1.3 0.0 4.7 2.2 1.5 1.4 10.1 18.6 2.2 4.1 2.8 1.9 807.7 6.5 2.3 1.8 9.4 1.8 2.9 3.1 9.5 16.6 0.9 3.9 5.7 1.5 1.2 3.4 2.0 0.8 23.0 0.0 0.6 0.7 30.6 20.2 1.2 0.9 1.9 1.9 1.6 2.7 1.4 WDR1 ENSG00000071127 "WD repeat domain 1" O75083 4 10074339-10116949 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 1232.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020804, HPA036434, HPA070293" Approved Supported "Plasma membrane,Cell Junctions" NA NA 63000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 34: Spermatids - Unknown function" "Plasma membrane, Cell Junctions" "CAB020804: , HPA036434: AB_2675121, HPA070293: AB_2732152" "unprognostic (1.35e-1)" "unprognostic (6.64e-2)" "unprognostic (5.31e-2)" "unprognostic (1.32e-3)" "unprognostic (2.65e-1)" "unprognostic (1.22e-1)" "unprognostic (2.63e-3)" "unprognostic (6.83e-3)" "unprognostic (1.69e-1)" "unprognostic (9.00e-3)" "unprognostic (2.52e-2)" "unprognostic (2.61e-1)" "prognostic favorable (1.73e-5)" "unprognostic (1.11e-1)" "unprognostic (3.56e-1)" "unprognostic (3.46e-2)" "unprognostic (4.83e-3)" 133.7 77.7 60.2 194.5 58.1 150.9 107.8 56.8 65.4 147.1 104.2 200.8 149.1 261.1 91.0 165.1 179.5 117.4 134.2 69.7 69.7 119.4 84.2 142.8 174.6 68.4 69.7 120.5 63.7 89.6 58.4 105.4 68.6 124.5 141.5 93.0 124.9 173.7 94.8 110.4 148.3 214.6 63.1 110.0 131.7 131.9 62.6 188.0 109.8 89.5 149.6 203.0 139.3 68.8 249.5 246.9 213.2 179.4 160.1 265.9 336.9 612.9 561.7 542.9 423.1 296.4 303.3 173.6 193.3 744.4 579.3 158.8 237.3 451.0 582.4 270.7 82.8 494.1 244.6 213.8 377.9 159.4 538.6 256.7 228.4 552.9 276.3 418.7 599.3 301.6 151.6 273.3 540.7 142.8 700.1 229.0 253.4 200.7 250.4 327.8 197.7 146.7 344.9 394.7 72.4 80.5 265.6 141.3 257.3 282.9 120.1 173.9 909.9 415.7 174.6 345.7 548.0 173.4 296.4 225.5 439.7 240.4 522.9 177.4 115.7 213.6 172.3 195.9 134.4 81.6 143.8 173.0 141.4 61.1 145.6 156.9 201.5 129.0 246.9 154.5 214.9 298.4 60.2 58.1 56.8 65.4 69.7 69.7 68.4 69.7 68.6 63.1 62.6 68.8 66.5 35.3 52.9 10.1 77.0 145.3 204.6 103.5 46.7 22.0 65.9 68.7 62.9 52.9 87.4 104.8 41.7 172.5 126.7 347.1 86.1 282.5 500.8 72.2 63.8 103.6 109.2 56.8 4.7 211.3 302.4 68.7 118.3 111.7 82.4 78.7 84.3 71.8 249.2 33.7 8.4 152.6 138.4 159.4 135.8 1232.1 46.9 174.9 80.0 15.0 303.7 82.6 147.2 11.6 9.6 322.8 244.4 92.2 78.3 150.7 169.0 113.1 73.5 28.0 98.6 46.1 168.1 81.6 64.3 74.9 137.0 231.6 132.2 77.2 172.8 193.6 WDR19 "DYF-2, FAP66, FLJ23127, IFT144, KIAA1638, NPHP13, ORF26, Oseg6, Pwdmp" ENSG00000157796 "WD repeat domain 19" Q8NEZ3 4 39182504-39285810 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Ectodermal dysplasia, Leber congenital amaurosis, Nephronophthisis, Senior-Loken syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 61.8;Inhibitory neurons: 82.5;Respiratory ciliated cells: 46.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC diff: 45.3;ASC TERT1: 47.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039616, HPA058847" Approved Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Centrosome, Cytosol" "HPA039616: AB_10796331, HPA058847: AB_2683834" "unprognostic (1.80e-1)" "unprognostic (9.32e-2)" "unprognostic (6.40e-2)" "unprognostic (5.69e-2)" "unprognostic (1.37e-1)" "unprognostic (1.26e-3)" "prognostic unfavorable (4.43e-4)" "unprognostic (1.06e-1)" "unprognostic (1.60e-1)" "unprognostic (9.63e-2)" "prognostic favorable (2.70e-4)" "prognostic unfavorable (8.58e-4)" "unprognostic (3.52e-2)" "unprognostic (2.40e-2)" "unprognostic (5.53e-2)" "unprognostic (1.82e-1)" "unprognostic (1.56e-2)" 7.5 8.0 3.1 5.3 2.5 3.7 9.2 5.3 3.8 10.5 10.8 6.8 1.9 16.0 13.3 3.9 20.3 8.4 4.2 2.3 2.5 8.8 6.3 8.8 4.7 5.3 3.6 17.9 5.4 8.1 9.1 6.2 2.9 7.7 4.2 13.0 5.7 8.4 2.3 5.5 4.7 9.1 3.5 4.6 6.2 14.0 2.7 6.9 16.7 2.4 4.9 6.2 6.8 3.6 6.1 5.2 10.3 12.1 45.3 47.0 4.7 7.5 17.2 8.1 10.6 2.8 6.5 10.4 4.1 7.8 17.2 4.0 10.9 5.4 8.6 0.5 8.5 2.2 10.3 6.1 16.1 9.6 2.6 30.5 11.1 11.9 7.2 24.6 10.7 11.0 8.7 9.1 9.9 2.1 7.7 8.1 3.5 3.7 5.6 8.2 10.4 4.2 7.0 2.9 11.5 10.4 10.2 2.4 6.1 13.1 5.5 3.6 7.9 7.9 5.3 17.5 7.8 7.2 7.6 7.6 11.9 3.3 3.7 0.1 0.3 0.2 0.3 0.5 0.3 0.8 0.5 0.6 0.3 1.2 0.5 0.6 0.3 0.8 0.5 0.1 0.3 0.2 3.1 2.5 5.3 3.8 2.3 2.5 5.3 3.6 2.9 3.5 2.7 3.6 5.5 12.8 9.3 26.1 5.4 4.8 4.9 4.6 2.2 10.1 7.3 7.4 4.5 2.8 9.4 18.4 10.4 1.2 1.8 0.7 0.0 5.5 5.1 32.3 14.6 6.7 2.4 4.0 61.8 3.6 3.2 10.8 2.0 12.0 2.5 13.4 4.2 10.0 3.2 25.2 82.5 2.0 12.2 3.2 3.6 3.4 16.4 3.0 1.8 19.7 1.8 6.7 1.0 18.1 19.7 2.9 0.2 18.8 3.9 3.0 0.3 4.0 46.6 21.7 0.0 10.9 7.9 33.8 10.2 3.9 4.7 1.4 2.9 13.1 1.1 1.9 WDR38 ENSG00000136918 "WD repeat domain 38" Q5JTN6 9 124853417-124857890 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "fallopian tube: 77.7" "Cell type enhanced" "Detected in some" "Early spermatids: 26.9;Endometrial ciliated cells: 93.3;Late spermatids: 92.6;Respiratory ciliated cells: 127.9" "Cancer enhanced" "Detected in some" "endometrial cancer: 12.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA056607 Approved Vesicles NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "HPA056607: AB_2683188" "unprognostic (5.66e-3)" "unprognostic (2.15e-3)" "unprognostic (1.51e-2)" "prognostic favorable (3.97e-4)" "unprognostic (1.14e-1)" "unprognostic (2.17e-3)" "unprognostic (4.29e-3)" "unprognostic (7.90e-2)" "unprognostic (1.13e-1)" "unprognostic (3.82e-1)" "unprognostic (1.38e-1)" "unprognostic (5.90e-2)" "unprognostic (7.75e-5)" "unprognostic (1.01e-1)" "unprognostic (3.25e-2)" "unprognostic (6.36e-2)" "unprognostic (4.42e-2)" 0.0 0.0 2.1 0.0 2.0 0.0 0.0 2.3 1.3 2.4 16.3 0.0 0.0 0.7 0.0 0.0 77.7 0.0 0.1 2.2 4.0 0.1 0.0 5.2 0.0 8.2 9.8 0.0 0.0 0.0 0.3 0.0 6.5 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.1 7.2 0.0 0.0 7.6 3.3 0.1 0.2 0.0 0.0 0.0 0.0 4.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 2.0 2.3 1.3 2.2 4.0 8.2 9.8 6.5 7.2 3.3 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.2 0.0 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 26.9 93.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 8.2 0.0 0.0 92.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 127.9 0.0 0.0 0.0 2.8 1.6 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.2 WDR5 "CFAP89, SWD3" ENSG00000196363 "WD repeat domain 5" P61964 9 134135365-134159968 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 152.7;Spermatocytes: 99.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047182 Supported Nucleoplasm NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "HPA047182: AB_2679971" "unprognostic (9.28e-2)" "unprognostic (1.89e-2)" "unprognostic (1.52e-2)" "unprognostic (1.73e-1)" "unprognostic (1.72e-1)" "unprognostic (2.20e-1)" "unprognostic (1.05e-3)" "unprognostic (2.26e-3)" "unprognostic (1.22e-1)" "unprognostic (1.05e-1)" "unprognostic (4.31e-3)" "unprognostic (4.63e-2)" "unprognostic (7.06e-2)" "unprognostic (5.91e-3)" "unprognostic (1.47e-1)" "unprognostic (3.22e-2)" "unprognostic (2.88e-2)" 17.5 18.4 17.4 13.9 18.2 20.3 16.7 20.1 21.0 17.1 17.3 19.3 17.6 18.7 8.9 24.9 18.9 8.3 19.5 17.8 18.0 18.6 34.0 15.4 16.2 15.9 16.9 21.9 27.7 13.5 25.4 14.7 16.5 18.9 13.7 9.1 18.1 12.7 33.9 22.2 19.4 13.5 15.0 20.0 20.6 38.7 18.4 17.8 17.7 18.2 18.0 18.4 16.3 17.9 43.6 52.4 49.0 56.1 26.1 28.7 77.4 43.0 28.3 57.5 39.1 61.3 34.9 68.8 26.7 35.2 50.5 105.9 66.9 44.1 46.6 46.4 45.6 39.7 85.6 49.9 27.9 90.0 40.2 27.7 41.0 43.1 52.6 23.7 38.7 67.5 75.3 37.6 40.5 116.1 77.4 73.6 62.3 98.3 65.2 83.4 99.2 65.2 28.3 42.0 81.7 42.5 64.8 50.2 29.7 32.5 69.1 78.3 33.9 58.7 53.8 54.5 70.5 19.6 40.0 74.0 34.1 60.4 48.2 0.9 9.3 1.6 6.7 6.0 6.6 4.6 6.6 6.9 10.0 5.8 6.8 5.4 0.8 4.9 5.1 8.3 6.4 7.1 17.4 18.2 20.1 21.0 17.8 18.0 15.9 16.9 16.5 15.0 18.4 17.9 8.2 9.6 8.6 10.7 11.8 11.9 14.9 7.0 16.5 9.6 13.6 12.8 9.5 11.5 5.0 5.5 22.9 27.4 8.9 9.1 9.8 14.7 152.7 8.6 14.4 9.6 6.6 17.5 16.4 20.9 42.5 12.2 15.3 10.0 8.9 17.6 5.3 21.9 19.1 8.4 16.6 13.7 8.2 6.3 9.8 41.4 11.5 10.9 5.4 11.2 10.0 6.8 10.3 10.1 14.3 16.7 9.7 11.7 26.6 30.4 17.6 10.2 3.9 7.4 6.6 9.7 10.9 99.9 42.3 25.6 16.3 17.8 9.7 32.5 22.2 18.0 WDR87 NYD-SP11 ENSG00000171804 "WD repeat domain 87" Q6ZQQ6 19 37884823-37906677 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 47 "testis: 17.0" "Group enriched" "Detected in some" 5 "Early spermatids: 33.1;Spermatocytes: 114.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (6.37e-3)" "unprognostic (1.26e-2)" "unprognostic (5.59e-2)" "unprognostic (1.11e-1)" "unprognostic (1.00e-1)" "unprognostic (1.89e-2)" "unprognostic (2.60e-1)" "unprognostic (4.22e-1)" "unprognostic (5.43e-2)" "unprognostic (2.58e-2)" "unprognostic (1.78e-8)" "unprognostic (1.19e-1)" "unprognostic (2.42e-1)" "unprognostic (5.48e-2)" "unprognostic (4.12e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 33.1 0.2 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 13.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 114.8 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 WDR92 "FLJ31741, Monad" ENSG00000243667 "WD repeat domain 92" Q96MX6 2 68122936-68157549 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 47.9;Respiratory ciliated cells: 40.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035335, HPA035336" Approved Approved Nucleoplasm NA NA "Cluster 15: NK-cells - Transcription" "Cluster 52: Non-specific - Ribosome" "Cluster 32: U-937 - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "HPA035335: AB_10959456, HPA035336: AB_10964348" "unprognostic (3.55e-2)" "unprognostic (3.42e-3)" "unprognostic (6.80e-2)" "unprognostic (1.69e-2)" "unprognostic (1.31e-1)" "unprognostic (3.20e-2)" "unprognostic (3.76e-3)" "unprognostic (2.51e-2)" "unprognostic (1.34e-1)" "unprognostic (2.01e-1)" "unprognostic (4.91e-2)" "unprognostic (3.61e-1)" "unprognostic (3.56e-3)" "unprognostic (9.86e-2)" "unprognostic (7.23e-2)" "unprognostic (4.07e-1)" "unprognostic (3.15e-2)" 6.0 7.0 4.9 6.6 6.4 3.6 8.6 7.6 5.5 5.4 10.4 6.1 6.3 7.4 16.0 7.0 11.1 5.3 9.0 5.0 4.9 5.5 5.2 5.8 9.7 5.7 7.2 6.9 4.3 7.2 4.7 5.7 4.6 8.1 8.0 6.9 6.4 6.8 11.4 10.5 5.3 7.5 5.2 8.2 5.9 8.0 4.7 8.1 8.3 9.1 8.9 5.0 5.1 5.5 15.3 9.4 12.0 12.6 14.5 14.7 10.3 11.6 10.1 12.1 12.8 7.0 12.5 16.5 3.7 10.3 16.5 15.0 13.0 8.8 15.6 11.2 13.8 16.9 13.1 8.0 7.0 18.5 5.2 9.4 11.5 10.0 8.6 12.9 11.7 15.2 11.3 11.1 14.3 7.3 13.2 18.6 12.2 12.8 12.9 15.9 15.3 14.1 12.5 8.6 12.4 10.6 8.6 15.5 9.6 11.8 11.9 12.1 13.6 18.4 7.4 11.6 10.1 7.6 11.6 11.6 17.3 17.6 9.3 0.7 2.3 1.7 3.2 2.5 4.2 5.3 3.4 3.8 2.7 4.9 4.0 5.0 1.0 6.3 1.8 5.1 4.0 2.1 4.9 6.4 7.6 5.5 5.0 4.9 5.7 7.2 4.6 5.2 4.7 5.5 7.8 3.2 10.9 5.9 5.2 3.4 4.7 6.5 2.2 28.7 5.6 5.6 3.1 1.5 11.1 5.5 47.9 13.6 12.2 1.3 1.9 6.7 5.8 26.3 6.8 7.4 0.0 7.0 17.9 6.5 9.2 5.7 1.5 4.3 13.3 9.7 8.2 6.3 7.3 11.8 16.4 3.3 4.1 3.5 1.2 2.8 7.8 3.5 1.8 8.4 7.2 12.0 6.2 14.1 11.6 6.2 2.9 9.4 2.0 3.3 3.7 6.7 40.2 21.9 6.6 9.0 5.9 26.0 15.2 1.8 4.1 5.1 3.6 9.4 6.0 2.1 WFDC1 PS20 ENSG00000103175 "WAP four-disulfide core domain 1" Q9HC57 16 84294846-84329844 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 99.8;seminal vesicle: 115.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 111.1;Fibroblasts: 72.6;Peritubular cells: 257.3;Smooth muscle cells: 95.8;Theca cells: 325.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 29.8;BJ: 20.5;HEL: 18.2;HeLa: 27.6;THP-1: 9.9;U-937: 10.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031411 Uncertain "Secreted to extracellular matrix" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 20: HeLa - Mitochondria" "Cluster 52: Non-specific - Transcription" "HPA031411: AB_10600921" "unprognostic (6.53e-2)" "unprognostic (1.27e-1)" "unprognostic (1.61e-2)" "unprognostic (8.66e-4)" "unprognostic (1.41e-2)" "unprognostic (1.50e-3)" "unprognostic (1.47e-2)" "unprognostic (3.11e-2)" "unprognostic (1.60e-1)" "unprognostic (2.88e-2)" "unprognostic (1.20e-1)" "unprognostic (1.12e-1)" "unprognostic (3.78e-2)" "unprognostic (5.49e-2)" "unprognostic (1.71e-1)" "unprognostic (6.74e-2)" "unprognostic (3.04e-1)" 8.1 26.9 16.5 10.5 16.5 1.9 4.3 19.1 21.2 21.5 12.9 79.3 8.9 17.3 18.8 24.5 7.9 35.1 4.4 16.1 15.5 16.7 5.5 29.5 0.6 17.0 16.2 3.7 1.0 0.4 5.7 99.8 15.3 69.0 17.4 8.4 6.2 115.1 1.2 3.2 14.6 32.2 14.9 3.5 20.8 12.5 16.3 0.3 4.8 1.6 0.8 54.2 13.5 14.9 0.0 0.0 4.4 29.8 0.0 0.1 0.2 20.5 2.5 0.0 0.0 0.0 0.0 0.0 5.6 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.2 27.6 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.5 0.0 0.4 0.0 0.0 2.3 0.0 0.0 5.3 0.1 0.0 0.5 3.2 0.1 0.1 9.9 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 10.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.5 16.5 19.1 21.2 16.1 15.5 17.0 16.2 15.3 14.9 16.3 14.9 3.4 3.2 0.5 9.1 0.0 1.8 0.9 0.1 0.0 111.1 2.0 0.9 1.4 0.0 0.1 1.8 0.0 2.1 0.1 0.9 11.7 0.0 27.8 0.6 10.6 3.9 4.2 0.0 4.1 0.0 2.0 72.6 7.7 0.5 0.0 0.2 12.5 0.0 6.6 5.0 0.9 4.7 0.0 0.0 3.0 41.1 15.8 2.3 0.0 2.8 0.0 1.4 0.0 29.1 0.6 0.1 0.6 257.3 0.3 1.3 0.4 1.3 0.7 4.2 0.0 1.0 95.8 5.5 0.9 0.1 0.4 3.8 0.5 325.9 3.1 1.0 WFDC5 "dJ211D12.5, WAP1" ENSG00000175121 "WAP four-disulfide core domain 5" Q8TCV5 20 45109452-45115172 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 29 "skin 1: 393.9" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 55.8;Early spermatids: 17.6;Late spermatids: 10.4;Suprabasal keratinocytes: 43.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 17.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 61: Skin - Cornification" "Cluster 28: Keratinocytes - Keratinization" "unprognostic (1.32e-1)" "unprognostic (3.22e-2)" "unprognostic (3.05e-1)" "unprognostic (1.54e-1)" "unprognostic (1.28e-4)" "unprognostic (6.59e-2)" "unprognostic (2.23e-2)" "prognostic unfavorable (2.32e-5)" "unprognostic (4.12e-2)" "unprognostic (2.17e-1)" "unprognostic (5.96e-2)" 0.2 0.0 0.0 0.0 0.0 0.0 9.8 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.1 0.1 0.0 0.7 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 1.6 1.5 1.2 393.9 0.0 0.0 0.2 0.0 0.0 2.8 0.0 0.6 0.0 0.0 13.3 0.3 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.0 0.0 0.0 55.8 0.4 2.5 0.6 0.0 0.1 0.0 0.0 0.0 0.4 1.8 0.0 0.0 0.0 0.1 0.0 0.0 17.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 10.4 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 3.0 43.2 0.0 0.1 0.0 0.1 0.2 WNK3 PRKWNK3 ENSG00000196632 "WNK lysine deficient protein kinase 3" Q9BYP7 X 54192823-54358642 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 11.7;testis: 9.9" "Group enriched" "Detected in many" 4 "Cardiomyocytes: 193.3;Granulosa cells: 199.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 4.5;AN3-CA: 3.4;HAP1: 5.2;NTERA-2: 9.1;SiHa: 4.5;SuSa: 3.8;U-2 OS: 3.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077678 Approved Approved Vesicles NA NA "Cluster 32: T-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" Vesicles "HPA077678: AB_2686850" "unprognostic (1.86e-1)" "unprognostic (1.68e-3)" "unprognostic (2.44e-1)" "unprognostic (7.87e-5)" "unprognostic (4.82e-3)" "unprognostic (1.85e-3)" "unprognostic (1.85e-2)" "unprognostic (3.32e-2)" "unprognostic (3.38e-1)" "unprognostic (3.03e-2)" "unprognostic (5.78e-4)" "unprognostic (2.22e-1)" "unprognostic (2.64e-2)" "unprognostic (5.61e-2)" "unprognostic (9.99e-2)" "unprognostic (7.63e-2)" "unprognostic (8.74e-2)" 0.2 2.5 1.6 0.1 1.7 0.1 0.6 0.3 1.9 0.6 0.0 0.3 0.2 0.5 11.7 0.2 0.8 0.3 0.7 1.0 4.6 1.0 3.6 0.3 0.1 1.6 4.8 3.0 0.3 0.9 2.4 0.3 2.4 0.9 0.0 3.3 0.3 0.8 0.1 0.3 0.2 0.5 0.6 0.2 0.6 9.9 4.5 0.1 0.6 0.1 0.1 0.5 0.4 1.2 0.0 0.0 4.5 3.4 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 1.8 0.0 5.2 0.1 0.2 0.0 0.9 0.0 0.0 0.1 0.1 0.0 0.1 0.3 0.0 0.1 0.0 0.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 2.2 0.6 0.0 0.9 0.1 1.4 1.3 4.5 0.0 0.5 3.8 0.4 0.0 0.2 0.0 3.9 0.0 1.0 0.0 3.3 0.0 1.2 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.7 0.3 1.9 1.0 4.6 1.6 4.8 2.4 0.6 4.5 1.2 1.9 0.0 2.3 18.3 0.7 3.7 4.3 0.3 9.1 24.9 5.8 6.9 193.3 2.8 3.2 7.3 14.6 0.2 0.0 0.1 5.9 1.7 6.4 2.0 7.8 8.5 0.0 0.8 14.5 0.0 0.3 6.7 0.0 4.9 6.3 199.5 20.3 48.3 0.1 35.3 29.7 0.0 2.0 0.8 1.5 20.4 15.8 0.6 0.0 3.7 0.0 19.5 0.0 48.2 19.2 0.2 0.0 43.6 0.0 6.0 0.0 3.9 0.2 43.3 6.6 4.8 10.5 43.8 46.3 2.1 1.1 0.1 1.5 9.8 0.0 1.4 WNT8A WNT8D ENSG00000061492 "Wnt family member 8A" Q9H1J5 5 138083990-138092365 "Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Excitatory neurons: 2.8;Inhibitory neurons: 1.5;Microglial cells: 1.0" "Cancer enriched" "Detected in single" 12 "testis cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SuSa: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA038539 Uncertain "Secreted to extracellular matrix" NA NA "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA038539: AB_10669646" "unprognostic (1.11e-5)" "unprognostic (4.11e-2)" "unprognostic (4.11e-2)" "unprognostic (5.32e-2)" 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 WNT8B ENSG00000075290 "Wnt family member 8B" Q93098 10 100463009-100483744 "Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "parathyroid gland: 1.2" "Cell type enhanced" "Detected in single" "Oligodendrocytes: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 2.3;JURKAT: 3.1;RPMI-8226: 1.0;SCLC-21H: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA036570 Uncertain "Secreted to extracellular matrix" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA036570: AB_10670113" "unprognostic (6.92e-2)" "unprognostic (1.57e-1)" "unprognostic (7.13e-2)" "unprognostic (6.67e-2)" "unprognostic (3.88e-1)" "unprognostic (1.90e-1)" "unprognostic (2.64e-1)" "unprognostic (9.16e-4)" "unprognostic (1.95e-2)" "unprognostic (1.02e-1)" "unprognostic (1.53e-1)" "unprognostic (7.83e-2)" "unprognostic (2.42e-3)" "unprognostic (5.02e-2)" "unprognostic (1.63e-1)" "unprognostic (2.68e-2)" "unprognostic (1.24e-2)" 0.0 0.8 0.1 0.0 0.4 0.0 0.1 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.1 0.4 1.2 0.1 0.0 0.0 0.2 0.0 0.9 0.6 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 2.3 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.1 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.1 0.0 3.1 0.0 0.2 0.0 0.6 0.8 0.0 0.0 0.0 0.1 0.2 0.0 1.0 0.0 0.7 1.1 0.3 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.2 0.4 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 WSB2 "MGC10210, SBA2" ENSG00000176871 "WD repeat and SOCS box containing 2" Q9NYS7 12 118032687-118062430 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 163.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052606 Uncertain NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 17: WM-115 - Nervous system development" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA052606: AB_2681882" "unprognostic (5.02e-3)" "unprognostic (4.57e-2)" "unprognostic (4.85e-2)" "unprognostic (1.25e-1)" "unprognostic (1.07e-1)" "unprognostic (4.91e-2)" "prognostic unfavorable (2.42e-5)" "unprognostic (2.42e-3)" "unprognostic (4.66e-3)" "unprognostic (7.29e-2)" "unprognostic (1.05e-1)" "unprognostic (2.93e-1)" "unprognostic (4.05e-1)" "unprognostic (2.92e-1)" "unprognostic (2.66e-1)" "unprognostic (2.79e-1)" "unprognostic (2.42e-2)" 33.8 46.8 94.4 29.8 102.1 17.6 20.2 85.2 117.5 19.6 53.2 44.7 35.3 18.7 23.8 53.0 17.9 25.3 55.8 103.0 83.8 35.5 36.6 31.5 24.1 100.3 106.3 13.8 36.7 43.0 36.1 19.2 96.4 26.6 45.3 38.9 20.9 26.4 102.7 23.0 39.0 35.7 95.2 17.7 33.0 18.6 99.4 20.8 46.5 163.3 28.3 45.6 21.1 95.4 49.3 78.2 55.2 93.5 81.1 46.7 39.1 129.3 95.9 138.6 82.8 41.5 66.4 7.1 42.6 168.7 77.4 25.8 46.6 78.6 98.7 90.7 29.6 27.5 36.7 39.0 85.7 16.2 71.5 62.7 77.7 75.0 51.6 148.7 72.3 48.5 83.2 12.5 143.8 73.2 10.3 9.9 32.2 110.7 48.2 29.3 57.5 2.2 81.9 211.5 58.5 87.3 100.1 21.8 69.9 54.7 75.0 37.3 113.7 164.6 68.7 53.1 158.8 21.6 14.6 13.4 148.8 20.3 266.9 9.7 5.0 11.5 4.5 7.5 4.0 0.7 4.4 4.7 3.5 1.8 1.9 3.4 5.4 3.4 5.2 4.1 5.1 1.8 94.4 102.1 85.2 117.5 103.0 83.8 100.3 106.3 96.4 95.2 99.4 95.4 17.1 25.6 15.7 14.7 5.9 16.6 39.4 16.4 5.2 21.0 20.2 10.3 33.7 24.3 14.1 20.2 4.2 10.0 11.8 75.1 21.5 37.4 2.0 19.5 23.6 16.7 72.7 7.4 45.9 85.1 24.3 19.6 23.0 31.5 7.0 13.1 17.2 36.4 34.7 57.2 31.9 40.7 22.4 51.8 18.4 4.7 7.5 23.5 28.4 18.7 34.8 34.1 11.3 18.1 30.7 89.6 44.5 17.3 6.2 53.4 47.7 35.6 7.2 14.1 13.1 21.8 26.0 3.2 5.1 17.8 18.6 17.2 13.1 44.8 25.8 86.9 WSCD1 KIAA0523 ENSG00000179314 "WSC domain containing 1" Q658N2 17 6057807-6124427 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 29.5" "Cell type enhanced" "Detected in many" "Early spermatids: 73.4;Late spermatids: 99.6;Oligodendrocyte precursor cells: 110.1" "Cancer enriched" "Detected in many" 4 "glioma: 18.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 40.0;HUVEC TERT2: 24.7;OE19: 26.4;PC-3: 24.8;RH-30: 50.5;SCLC-21H: 15.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015919 Uncertain Approved "Nucleoplasm,Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm "Golgi apparatus" "HPA015919: AB_2216211" "unprognostic (1.50e-1)" "unprognostic (7.10e-2)" "unprognostic (5.32e-2)" "unprognostic (1.15e-2)" "unprognostic (2.61e-1)" "unprognostic (4.18e-2)" "unprognostic (4.53e-2)" "unprognostic (1.61e-1)" "unprognostic (3.59e-2)" "unprognostic (1.69e-1)" "unprognostic (3.46e-4)" "unprognostic (2.08e-1)" "unprognostic (1.18e-2)" "unprognostic (4.13e-2)" "unprognostic (1.67e-1)" "unprognostic (1.19e-1)" "unprognostic (1.62e-2)" 2.2 2.2 19.7 1.0 21.7 0.0 1.8 29.5 19.8 1.1 6.8 6.8 3.4 1.2 0.2 0.6 1.0 0.9 2.0 18.1 19.1 5.9 0.5 1.4 1.3 29.4 23.8 0.5 1.5 0.9 3.5 4.8 24.9 0.6 3.8 5.7 1.2 0.7 11.4 1.3 4.3 1.3 22.2 13.6 1.3 11.2 22.9 1.1 0.9 3.8 0.9 0.8 0.8 26.7 0.0 5.8 40.0 3.2 0.2 0.0 2.1 4.3 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.4 10.0 0.3 0.0 0.0 13.6 0.0 0.0 0.3 0.3 0.0 0.0 0.2 0.0 0.0 0.5 0.0 24.7 0.1 0.0 0.9 1.2 0.8 0.0 0.0 13.3 26.4 24.8 0.0 50.5 1.6 8.4 2.1 15.5 0.0 0.2 0.0 0.0 4.1 0.0 0.3 0.1 0.0 1.4 0.0 0.2 0.0 1.6 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.7 21.7 29.5 19.8 18.1 19.1 29.4 23.8 24.9 22.2 22.9 26.7 7.7 0.0 0.0 11.8 0.1 0.4 0.0 0.0 0.6 24.1 0.2 0.1 3.8 0.0 0.0 1.8 0.0 0.7 0.1 22.4 1.9 0.3 73.4 0.1 0.0 5.9 0.0 0.0 2.7 0.2 0.1 0.2 0.0 0.0 0.0 0.7 10.0 0.4 1.2 1.7 12.5 3.3 0.0 0.8 0.4 99.6 0.6 0.0 1.8 4.7 0.0 9.8 0.0 110.1 20.6 0.2 6.5 0.0 0.0 0.0 21.5 1.4 0.0 3.5 0.0 6.0 0.7 0.4 3.3 0.1 0.6 0.0 0.3 0.1 5.8 0.1 WWC1 "KIAA0869, KIBRA, PPP1R168" ENSG00000113645 "WW and C2 domain containing 1" Q8IX03 5 168291645-168472303 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 142.3" "Cell type enhanced" "Detected in many" "Astrocytes: 162.2;Cone photoreceptor cells: 91.8;Endometrial ciliated cells: 81.8;Glandular and luminal cells: 149.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 120.2;RPTEC TERT1: 260.4;SK-BR-3: 136.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038016, HPA038017" Approved Approved "Golgi apparatus" NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" "Golgi apparatus" "HPA038016: AB_10697091, HPA038017: AB_10669513" "unprognostic (3.60e-1)" "unprognostic (2.24e-2)" "unprognostic (1.08e-1)" "unprognostic (9.92e-2)" "unprognostic (1.51e-1)" "unprognostic (6.77e-3)" "unprognostic (2.89e-1)" "unprognostic (3.50e-2)" "unprognostic (1.47e-1)" "unprognostic (1.34e-1)" "unprognostic (3.31e-2)" "unprognostic (7.38e-2)" "prognostic favorable (1.95e-8)" "unprognostic (2.81e-3)" "unprognostic (1.80e-1)" "unprognostic (2.77e-1)" "unprognostic (1.50e-1)" 7.8 0.6 41.8 2.9 43.3 0.1 21.2 41.0 39.7 6.0 50.4 6.4 24.3 2.8 6.8 22.9 17.2 8.7 1.6 40.3 41.3 73.3 38.1 20.2 3.0 56.8 47.0 0.8 28.3 23.5 7.8 10.2 43.6 16.4 6.1 17.8 142.3 11.8 0.0 19.9 20.2 1.1 46.6 0.7 22.9 1.7 54.3 1.3 29.7 0.0 6.9 9.3 10.1 38.6 50.6 56.4 9.2 0.4 0.0 0.0 96.8 3.7 0.9 17.1 15.3 120.2 73.6 0.0 58.6 1.2 47.4 35.0 18.9 46.1 20.1 0.1 18.6 0.0 28.6 29.9 0.9 4.4 0.0 6.0 13.9 32.3 28.5 13.2 0.0 3.0 0.0 7.2 1.3 56.4 0.0 0.1 13.3 60.8 8.2 0.0 0.4 29.1 260.4 68.8 30.7 11.4 66.5 136.4 17.1 11.6 67.8 4.3 0.0 3.0 34.2 0.4 36.9 0.8 0.4 0.2 3.4 0.1 8.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 41.8 43.3 41.0 39.7 40.3 41.3 56.8 47.0 43.6 46.6 54.3 38.6 0.3 64.1 72.3 162.2 1.3 11.9 14.7 6.0 1.8 1.4 35.7 25.7 1.8 34.3 42.1 58.8 91.8 11.6 0.6 17.9 13.7 44.9 0.4 81.8 10.8 1.3 7.8 0.0 50.1 40.5 2.3 5.3 15.3 149.2 1.3 5.6 1.1 16.9 1.3 0.0 27.9 7.8 6.1 0.6 1.1 0.1 1.2 4.2 10.6 8.4 1.1 18.1 0.0 17.6 1.9 73.1 10.9 0.7 0.1 38.8 18.9 61.8 36.7 9.1 0.0 0.2 5.6 0.3 5.0 7.3 13.9 18.2 2.1 2.5 12.2 16.5 XAB2 "HCNP, HCRN, NTC90, SYF1" ENSG00000076924 "XPA binding protein 2" Q9HCS7 19 7619525-7629545 "Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, mRNA processing, mRNA splicing, Transcription" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 159.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048751 Supported Nucleoplasm,Vesicles NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 71: Testis - DNA repair" "Cluster 29: U-266 - Adaptive immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm Vesicles "HPA048751: AB_2680512" "unprognostic (1.13e-1)" "prognostic favorable (4.04e-4)" "unprognostic (1.99e-3)" "prognostic favorable (4.96e-4)" "unprognostic (1.35e-1)" "unprognostic (4.98e-3)" "unprognostic (4.95e-2)" "unprognostic (4.56e-3)" "unprognostic (1.40e-1)" "unprognostic (2.10e-1)" "prognostic favorable (7.47e-4)" "unprognostic (2.69e-1)" "unprognostic (7.43e-3)" "unprognostic (3.88e-2)" "unprognostic (1.61e-1)" "unprognostic (1.51e-1)" "unprognostic (1.80e-3)" 29.4 23.6 17.7 15.1 19.9 44.5 30.6 19.6 24.8 37.0 16.9 28.3 17.5 33.8 6.9 25.4 32.0 11.8 24.3 17.8 17.9 27.7 27.8 27.2 20.7 19.9 18.0 45.8 35.9 13.4 27.1 15.4 20.2 32.7 5.4 9.0 31.1 17.5 35.6 39.0 27.6 9.3 18.6 34.5 30.9 37.7 18.3 21.1 34.7 13.3 10.6 29.1 29.6 25.5 39.8 35.7 21.2 27.9 21.9 16.3 41.2 22.8 26.5 39.6 40.0 46.4 25.4 26.7 44.1 21.3 28.9 34.2 30.2 33.2 10.0 47.1 39.0 35.5 30.2 41.3 28.3 47.5 30.8 28.8 27.0 28.0 20.2 21.3 24.2 56.4 32.4 69.0 12.4 44.0 44.9 73.8 48.3 24.8 69.6 49.3 26.8 47.0 15.8 30.7 30.2 34.4 25.9 25.1 23.2 13.8 32.0 41.6 24.1 18.1 29.5 41.3 39.0 117.7 75.0 39.0 31.0 40.1 27.4 8.8 10.0 9.3 11.8 10.2 11.3 10.1 11.0 9.1 8.0 12.2 13.1 10.0 6.4 8.3 13.9 6.9 14.2 12.1 17.7 19.9 19.6 24.8 17.8 17.9 19.9 18.0 20.2 18.6 18.3 25.5 18.3 0.0 1.8 3.9 22.9 19.6 16.2 28.1 14.2 14.1 89.4 54.4 1.4 25.8 20.1 47.8 12.5 46.0 24.8 28.3 35.2 19.8 39.9 24.7 13.3 16.4 18.6 14.1 2.3 34.4 26.4 16.7 33.6 32.3 19.7 27.7 17.5 46.4 19.8 3.3 2.5 21.2 24.4 19.2 11.0 19.1 28.3 18.3 26.6 3.7 26.5 13.9 23.7 1.0 3.7 15.1 12.4 21.8 19.4 12.2 28.9 159.5 13.4 14.2 39.5 15.9 21.6 36.1 57.3 14.6 17.8 65.9 20.6 17.8 23.9 14.3 XPO5 KIAA1291 ENSG00000124571 "Exportin 5" Q9HAV4 6 43522334-43576038 "Predicted intracellular proteins, Transporters" "Host-virus interaction, Protein transport, RNA-mediated gene silencing, Transport" "RNA-binding, tRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012357, HPA018402, HPA023959, HPA029909" Enhanced Enhanced Nucleoplasm NA NA 13000 "Cluster 27: Non-specific - Gene expression" "Cluster 23: Testis - Cell cycle regulation" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "CAB012357: , HPA018402: AB_1848330, HPA023959: AB_1848331, HPA029909: AB_10611245" "unprognostic (6.98e-2)" "unprognostic (4.34e-2)" "unprognostic (5.13e-2)" "prognostic unfavorable (4.94e-7)" "unprognostic (6.16e-2)" "unprognostic (2.43e-2)" "prognostic unfavorable (3.98e-8)" "unprognostic (4.78e-1)" "unprognostic (4.72e-3)" "unprognostic (1.72e-1)" "unprognostic (4.86e-2)" "unprognostic (1.49e-1)" "unprognostic (1.07e-2)" "unprognostic (1.97e-1)" "unprognostic (1.45e-1)" "unprognostic (9.48e-2)" "unprognostic (5.66e-3)" 7.3 8.0 4.6 9.1 5.3 8.3 8.5 5.1 5.8 7.6 4.1 7.2 6.3 8.0 9.1 12.0 6.9 5.8 7.0 4.7 4.7 7.4 6.7 6.5 8.7 4.8 4.6 6.3 14.0 11.1 6.5 7.6 4.5 7.9 8.8 11.7 8.1 7.1 11.2 12.3 6.4 9.7 4.2 6.9 8.3 23.7 5.2 12.0 13.1 6.0 11.2 11.2 7.9 4.7 48.8 28.5 46.7 94.4 23.7 19.9 43.3 24.8 17.3 47.9 34.4 79.1 16.5 65.6 31.4 23.7 45.1 40.8 78.4 36.2 53.5 48.0 61.9 63.6 34.5 57.8 34.0 71.0 32.6 14.5 36.8 50.4 78.0 17.2 34.6 46.0 138.5 50.2 32.6 59.5 53.9 35.1 50.1 132.3 28.7 57.9 49.5 49.2 27.6 37.6 95.7 39.7 34.5 31.5 44.7 40.6 36.3 56.1 29.2 35.2 41.9 34.0 52.8 31.8 37.1 126.3 12.6 60.7 38.4 0.0 4.3 3.1 4.8 5.4 4.4 2.8 4.3 5.3 4.9 2.4 3.4 4.6 0.4 7.1 10.8 1.4 4.7 4.0 4.6 5.3 5.1 5.8 4.7 4.7 4.8 4.6 4.5 4.2 5.2 4.7 4.7 6.4 3.3 21.2 6.0 8.9 6.8 4.6 5.2 11.3 7.0 7.4 6.5 2.8 3.5 11.0 8.4 5.5 8.4 3.6 1.9 6.7 12.3 7.1 10.9 6.6 14.4 9.4 31.7 7.7 6.5 7.5 10.2 7.5 11.4 13.4 2.5 4.6 6.2 21.9 35.2 5.9 2.0 5.3 2.5 13.5 4.1 4.9 1.8 25.3 5.1 4.5 13.4 26.7 32.0 6.6 2.2 8.2 10.8 13.0 4.1 4.7 5.5 14.3 0.0 10.0 7.3 26.9 23.5 10.2 7.1 4.4 5.4 11.5 7.2 5.8 XRCC6 "D22S671, D22S731, G22P1, KU70, ML8" ENSG00000196419 "X-ray repair cross complementing 6" P12956 22 41621163-41664048 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Host-virus interaction, Immunity, Innate immunity, Transcription, Transcription regulation" "Activator, DNA-binding, Helicase, Hydrolase, Lyase, Multifunctional enzyme" "Cancer-related genes, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 579.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004254, HPA047549, HPA062226" Enhanced Enhanced Nucleoplasm No No 700000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 23: Testis - Cell cycle regulation" "Cluster 21: OE19 - Mitochondria" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "CAB004254: AB_628453, HPA047549: AB_2680085, HPA062226: AB_2684716" "unprognostic (5.55e-2)" "unprognostic (2.39e-2)" "unprognostic (1.82e-3)" "unprognostic (2.39e-1)" "unprognostic (2.47e-2)" "unprognostic (9.17e-2)" "unprognostic (1.16e-3)" "unprognostic (2.32e-2)" "unprognostic (2.21e-1)" "unprognostic (2.11e-1)" "unprognostic (1.89e-2)" "unprognostic (1.33e-1)" "unprognostic (2.06e-3)" "unprognostic (1.22e-1)" "unprognostic (2.28e-1)" "unprognostic (4.77e-2)" "unprognostic (7.95e-2)" 143.7 183.4 84.9 153.4 89.3 218.2 143.3 87.8 100.8 152.1 87.2 159.5 136.8 153.8 111.3 192.1 151.4 105.5 176.1 89.2 94.7 136.9 142.4 133.2 196.6 89.5 86.8 169.8 119.0 156.5 122.6 155.0 92.2 132.7 164.9 115.6 130.8 144.4 273.0 168.3 142.8 161.0 93.5 143.1 138.6 231.2 87.9 224.1 137.8 184.3 222.2 162.6 142.0 96.4 554.6 388.0 527.9 455.5 313.5 279.5 413.8 394.7 464.6 794.9 656.4 570.4 335.7 886.2 319.8 478.1 357.4 400.6 739.2 486.8 803.2 493.4 921.2 478.8 435.2 559.5 281.5 1142.2 520.5 252.7 323.1 501.2 275.0 319.8 505.6 371.6 470.2 360.1 523.1 589.9 589.0 390.6 482.1 1138.4 452.1 660.0 562.3 695.6 440.4 404.4 243.3 174.6 644.1 328.2 455.7 392.9 382.2 439.0 366.2 394.3 546.2 354.0 522.4 354.0 671.9 896.1 369.4 441.3 476.4 146.0 264.3 227.6 243.6 296.5 258.4 256.5 269.5 269.2 324.1 246.9 293.2 262.5 69.2 253.2 307.0 191.7 325.9 600.8 84.9 89.3 87.8 100.8 89.2 94.7 89.5 86.8 92.2 93.5 87.9 96.4 96.6 96.1 142.5 18.6 132.6 124.0 201.0 219.0 83.1 107.1 80.1 83.4 89.4 115.8 160.4 82.8 62.6 422.3 104.9 97.3 166.3 205.4 119.6 86.1 87.0 117.0 98.6 125.4 24.5 182.7 317.2 123.9 73.4 105.9 119.7 156.4 70.3 103.7 170.2 87.5 29.5 114.7 166.8 98.1 116.7 62.9 126.8 110.4 88.9 17.8 182.8 149.7 89.6 26.2 30.5 150.9 106.6 126.7 116.0 112.0 113.7 140.3 112.6 103.6 164.3 102.4 127.4 579.8 314.4 91.5 102.1 362.2 136.9 150.6 166.8 137.5 YBX3 "CSDA, CSDA1, dbpA, ZONAB" ENSG00000060138 "Y-box binding protein 3" P16989 12 10699089-10723323 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "skeletal muscle: 4915.7;tongue: 1635.6" "Cell type enhanced" "Detected in many" "Early spermatids: 1418.1;Prostatic glandular cells: 1553.4;Skeletal myocytes: 1316.7;Urothelial cells: 1339.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 6.5" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034838 Approved Supported Cytosol NA NA 230000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "HPA034838: AB_10670980" "unprognostic (1.93e-2)" "unprognostic (6.20e-2)" "unprognostic (3.56e-1)" "unprognostic (3.61e-2)" "unprognostic (4.15e-1)" "unprognostic (4.33e-2)" "unprognostic (1.10e-1)" "unprognostic (3.81e-2)" "unprognostic (2.91e-1)" "unprognostic (2.41e-1)" "unprognostic (3.23e-3)" "unprognostic (1.20e-1)" "prognostic unfavorable (6.17e-13)" "unprognostic (2.11e-2)" "unprognostic (1.51e-1)" "unprognostic (4.25e-2)" "unprognostic (2.44e-1)" 250.4 96.7 17.6 77.5 17.6 151.1 200.2 18.8 25.5 152.1 28.4 249.1 37.5 136.8 47.3 271.0 166.7 65.0 469.9 16.5 22.3 194.1 53.8 209.5 32.9 25.4 22.4 134.6 291.0 18.6 84.1 72.5 23.9 177.1 58.8 82.8 218.1 67.5 4915.7 358.1 99.0 100.9 20.9 79.5 149.7 265.7 22.2 36.7 136.1 1635.6 54.6 225.4 204.8 19.7 117.2 90.3 41.4 136.1 165.7 310.7 307.4 173.4 142.7 138.7 132.0 160.4 259.5 109.3 57.7 130.3 96.5 215.5 173.3 338.1 124.6 1.2 325.2 91.3 123.6 108.4 198.3 171.7 10.4 343.3 452.3 124.2 414.6 148.9 313.6 152.3 123.1 0.4 154.7 112.6 137.8 141.9 435.5 103.7 76.9 76.9 192.6 127.4 192.6 150.0 52.2 0.3 129.1 130.9 174.1 288.0 37.1 133.9 221.3 94.5 282.6 108.4 201.5 0.5 38.1 13.4 133.1 0.2 104.8 0.0 4.2 0.0 0.6 4.2 0.0 1.6 0.0 1.5 3.2 6.5 0.0 1.6 0.8 0.8 2.4 0.1 0.1 1.0 17.6 17.6 18.8 25.5 16.5 22.3 25.4 22.4 23.9 20.9 22.2 19.7 680.9 150.6 164.4 14.0 192.8 764.9 1226.9 212.9 552.7 36.1 288.8 292.7 497.7 105.8 177.8 145.3 89.6 145.7 39.2 94.3 133.1 125.3 1418.1 563.0 402.1 563.1 67.6 1081.5 2.4 143.3 84.3 484.8 119.8 551.3 63.3 291.0 235.6 23.1 97.7 16.8 1.0 139.5 120.1 223.2 494.7 470.2 264.7 292.2 259.7 21.5 83.9 67.2 2.1 4.5 0.1 122.0 76.3 223.8 80.6 1553.4 43.9 240.4 240.4 365.4 124.9 1316.7 643.1 594.6 158.4 638.6 1050.5 125.7 72.5 70.8 157.4 1339.7 YIPF3 "C6orf109, dJ337H4.3, DKFZp566C243, FinGER3, KLIP1" ENSG00000137207 "Yip1 domain family member 3" Q9GZM5 6 43511832-43516985 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 494.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014859, HPA063699" Supported Enhanced "Nucleoplasm,Golgi apparatus" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 22: Non-specific - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 55: Plasma cells - Humoral immune response" "Golgi apparatus" Nucleoplasm "HPA014859: AB_1845729, HPA063699: AB_2685095" "unprognostic (2.82e-2)" "unprognostic (1.29e-1)" "unprognostic (2.29e-2)" "unprognostic (4.71e-2)" "unprognostic (1.74e-1)" "unprognostic (2.05e-1)" "unprognostic (2.15e-3)" "unprognostic (3.77e-1)" "unprognostic (1.33e-1)" "unprognostic (1.70e-3)" "unprognostic (1.70e-2)" "unprognostic (1.12e-1)" "unprognostic (1.40e-1)" "unprognostic (1.94e-2)" "unprognostic (3.55e-1)" "unprognostic (1.21e-1)" "unprognostic (1.10e-1)" 72.3 120.2 78.9 43.3 79.9 46.4 70.0 79.5 92.0 74.0 102.6 74.3 65.2 72.1 100.5 80.3 69.7 63.3 87.6 80.2 78.9 78.2 105.4 68.9 42.6 80.5 79.2 75.6 152.0 110.0 91.9 77.8 81.2 76.3 62.1 49.8 118.6 61.1 82.8 70.0 66.1 57.5 78.3 67.2 106.1 48.0 81.6 46.0 74.3 83.4 46.5 69.1 67.3 80.8 95.0 66.2 95.3 185.4 208.3 168.5 56.1 111.9 174.6 91.8 115.7 79.1 67.6 37.8 84.4 208.6 78.4 93.4 71.0 110.2 59.4 69.9 95.7 61.2 91.8 153.2 163.2 64.7 85.9 169.0 141.2 77.9 78.3 154.4 141.1 61.1 67.8 88.2 111.5 146.9 47.5 82.3 49.7 494.4 71.1 42.6 43.0 103.2 164.3 101.4 76.7 109.0 50.3 66.9 122.2 72.8 111.4 133.5 133.5 103.1 53.4 57.0 78.8 102.5 88.8 74.3 73.2 53.5 71.5 147.2 84.8 128.7 60.0 82.2 52.3 46.1 53.7 54.1 78.7 48.5 42.7 48.5 316.0 65.5 83.2 70.3 79.8 78.2 78.9 79.9 79.5 92.0 80.2 78.9 80.5 79.2 81.2 78.3 81.6 80.8 77.8 35.3 33.6 12.7 41.4 40.7 63.8 121.7 63.2 54.6 62.8 49.4 31.7 82.9 86.5 55.2 37.5 192.2 41.1 109.7 49.0 149.6 38.1 63.5 60.5 78.9 107.1 42.1 12.1 101.8 209.5 78.2 59.7 67.9 40.6 77.9 74.6 71.0 99.3 58.9 14.7 117.6 101.7 49.1 31.2 79.0 69.9 49.6 65.8 14.0 72.4 115.0 42.2 15.1 17.7 117.5 108.8 67.0 111.6 71.4 129.1 74.9 51.2 63.5 32.9 45.5 64.4 44.0 40.8 52.8 35.5 264.1 34.9 101.9 80.0 81.6 YPEL4 FLJ30213 ENSG00000166793 "Yippee like 4" Q96NS1 11 57645087-57649944 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 34.0;Early spermatids: 29.7;Erythroid cells: 92.4;Langerhans cells: 15.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 3.2;ASC diff: 2.1;SK-MEL-30: 4.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045621 Uncertain NA NA "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 6: Erythroid cells - Oxygen transport" "HPA045621: " "unprognostic (6.91e-3)" "unprognostic (1.74e-1)" "unprognostic (2.51e-2)" "unprognostic (8.62e-3)" "unprognostic (2.40e-1)" "unprognostic (7.50e-2)" "unprognostic (2.11e-2)" "unprognostic (2.47e-1)" "unprognostic (4.28e-2)" "unprognostic (1.04e-1)" "unprognostic (2.14e-1)" "unprognostic (4.18e-1)" "unprognostic (1.34e-6)" "unprognostic (1.50e-4)" "unprognostic (9.56e-2)" "unprognostic (1.86e-3)" "unprognostic (2.92e-1)" 1.6 3.3 9.6 0.3 12.8 7.2 1.9 11.7 23.2 4.8 0.0 1.9 0.4 3.6 0.2 0.6 1.9 1.2 0.8 12.3 10.5 0.7 0.4 1.6 0.2 11.3 6.9 5.4 0.4 0.1 5.4 0.7 11.0 0.8 0.2 3.2 0.7 0.4 0.4 0.9 1.1 1.3 4.3 1.2 0.8 2.4 7.7 0.3 0.8 0.7 0.1 0.8 2.8 16.5 0.2 0.1 3.2 0.2 2.1 1.9 0.4 0.1 1.7 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 1.8 0.9 0.1 0.3 0.0 1.8 0.0 0.7 0.0 0.2 0.1 0.0 0.7 0.3 1.2 0.0 0.1 1.3 0.3 0.2 0.0 0.0 0.0 0.8 0.1 0.1 4.4 1.8 0.3 0.0 0.0 0.1 0.7 0.0 0.0 1.4 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 9.6 12.8 11.7 23.2 12.3 10.5 11.3 6.9 11.0 4.3 7.7 16.5 0.7 0.0 0.0 1.0 0.9 1.1 0.8 0.1 0.6 34.0 0.0 0.4 0.6 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.0 0.6 29.7 0.6 1.7 1.2 0.0 92.4 13.4 0.0 0.6 4.3 0.5 0.6 3.8 0.1 0.4 0.1 1.0 8.4 15.0 0.0 0.0 1.3 15.7 12.8 1.2 3.3 5.4 1.0 0.1 1.0 0.0 5.5 12.3 0.1 0.0 0.4 0.4 0.2 0.0 0.0 0.0 2.8 0.0 4.4 2.6 0.3 0.1 0.4 1.3 3.3 2.5 0.1 0.0 0.1 YTHDC2 "DKFZp564A186, FLJ10053, FLJ2194" ENSG00000047188 "YTH domain containing 2" Q9H6S0 5 113513694-113595285 "Enzymes, Predicted intracellular proteins" "Differentiation, Meiosis, Oogenesis, Spermatogenesis" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 129.8;Inhibitory neurons: 146.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037364, HPA072678" Approved Approved "Nucleoplasm,Nuclear bodies,Cytoplasmic bodies" NA NA "Cluster 37: B-cells - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "Nuclear bodies, Cytoplasmic bodies" "HPA037364: AB_10672788, HPA072678: AB_2686548" "unprognostic (2.09e-1)" "unprognostic (2.10e-1)" "prognostic favorable (1.82e-5)" "unprognostic (4.33e-3)" "unprognostic (1.45e-1)" "unprognostic (6.48e-3)" "unprognostic (1.96e-1)" "unprognostic (7.82e-3)" "unprognostic (3.55e-2)" "unprognostic (8.56e-3)" "unprognostic (4.61e-2)" "unprognostic (2.03e-1)" "unprognostic (4.15e-2)" "unprognostic (3.05e-1)" "unprognostic (9.96e-2)" "unprognostic (1.08e-2)" "unprognostic (2.56e-2)" 8.4 9.7 5.2 11.3 5.8 9.9 10.1 8.8 6.6 8.9 7.8 8.7 9.3 9.2 8.6 9.4 8.3 8.0 7.6 6.1 5.1 8.5 12.6 7.4 13.8 5.3 5.8 11.0 8.7 15.5 8.7 6.9 5.3 8.1 10.0 18.3 8.9 7.4 11.5 11.3 10.1 7.9 5.1 11.4 9.2 14.8 4.7 10.2 9.2 10.9 12.9 9.8 8.9 7.1 16.0 14.2 18.1 30.7 9.8 12.9 19.7 12.1 13.4 15.2 23.6 10.0 8.8 29.1 8.5 10.2 19.5 15.3 22.0 27.2 19.8 12.6 19.9 15.8 25.8 13.6 14.5 12.8 13.4 10.6 10.3 9.6 17.4 14.3 21.5 13.0 15.8 13.0 13.6 5.3 17.8 9.1 8.4 4.7 9.2 7.4 15.6 22.7 12.7 20.9 14.4 12.0 16.3 11.7 12.7 11.3 16.6 11.4 18.8 23.2 8.1 12.1 16.7 13.3 18.0 18.0 13.3 14.4 10.1 0.0 2.8 2.9 2.8 1.9 3.3 7.3 3.2 3.0 2.4 5.1 3.4 2.9 1.0 4.3 3.3 3.6 2.6 1.2 5.2 5.8 8.8 6.6 6.1 5.1 5.3 5.8 5.3 5.1 4.7 7.1 27.4 28.9 32.8 61.0 39.6 13.3 21.8 14.7 15.9 59.9 17.6 17.7 17.7 14.3 25.3 12.9 83.4 13.7 34.0 12.3 0.0 17.8 47.5 15.5 24.5 24.0 7.2 16.6 129.8 18.6 8.3 22.4 34.1 17.2 12.6 69.0 20.0 25.7 17.3 52.2 146.3 14.2 20.3 30.0 13.2 44.2 19.9 26.8 12.4 95.5 23.9 21.4 16.5 94.5 97.6 18.0 7.8 14.7 20.0 14.4 16.0 17.8 24.9 88.9 26.3 34.0 26.6 93.8 37.8 19.2 14.3 18.1 33.0 33.4 16.7 18.5 YY1AP1 "HCCA2, YAP, YY1AP" ENSG00000163374 "YY1 associated protein 1" Q9H869 1 155659443-155689000 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA006986, HPA064249" Uncertain Approved "Nucleoli fibrillar center" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 43: THP-1 - Innate immune response" "Cluster 59: Non-specific - Transcription" "Nucleoli fibrillar center" "HPA006986: AB_1080620, HPA064249: AB_2685226" "unprognostic (1.96e-2)" "unprognostic (2.80e-1)" "unprognostic (1.09e-2)" "unprognostic (5.67e-2)" "unprognostic (3.91e-2)" "unprognostic (1.77e-1)" "unprognostic (2.86e-3)" "unprognostic (1.23e-1)" "unprognostic (6.95e-2)" "unprognostic (8.13e-2)" "unprognostic (6.87e-2)" "unprognostic (8.65e-2)" "prognostic unfavorable (2.01e-6)" "unprognostic (6.81e-2)" "unprognostic (2.10e-1)" "unprognostic (3.39e-1)" "unprognostic (5.84e-2)" 41.9 36.1 35.4 28.1 38.6 77.2 42.8 51.1 41.6 47.1 20.7 56.6 23.5 41.5 38.6 53.0 44.2 26.7 48.1 33.5 32.7 42.3 38.3 49.3 38.6 32.6 35.2 47.5 37.6 35.4 47.1 32.0 32.4 46.3 35.6 41.3 41.0 37.6 113.8 54.0 39.7 42.6 31.7 47.9 41.8 74.6 38.8 50.4 39.9 73.2 49.8 45.8 45.8 41.3 63.5 32.0 40.3 45.9 44.9 40.4 86.5 39.9 58.0 70.4 59.9 49.3 65.7 50.1 38.4 58.6 35.8 60.5 61.3 55.7 66.2 46.7 30.5 41.6 36.2 31.2 47.5 66.7 54.2 43.0 56.1 53.7 68.5 48.8 44.3 47.5 55.8 69.9 52.2 56.0 68.5 32.4 63.7 86.5 46.4 53.7 34.9 80.4 42.7 45.5 40.3 47.8 52.6 75.0 51.5 72.5 82.3 108.7 36.0 39.4 34.6 41.4 53.5 87.7 62.8 123.2 38.9 43.0 46.4 40.3 27.6 50.3 34.7 27.5 36.8 26.7 29.6 36.4 34.0 20.9 25.5 25.5 29.5 45.0 27.7 15.9 40.1 35.1 35.4 38.6 51.1 41.6 33.5 32.7 32.6 35.2 32.4 31.7 38.8 41.3 18.3 19.2 26.7 28.7 26.0 34.7 30.5 20.2 38.7 24.5 27.4 21.3 23.2 22.8 22.9 12.9 43.8 23.6 24.5 25.7 13.7 17.3 68.0 20.0 21.8 24.5 34.9 42.9 33.8 19.1 27.9 24.7 25.0 25.5 25.3 16.6 15.7 23.1 21.5 16.8 34.8 23.8 12.2 20.8 36.3 81.0 28.0 28.5 19.6 37.5 27.4 20.8 15.5 38.7 48.3 18.4 16.2 25.6 36.9 29.2 22.5 11.7 17.3 24.9 6.6 24.9 22.3 77.6 25.5 38.8 35.7 45.0 26.7 26.6 24.4 33.8 ZAR1 Z3CXXC6 ENSG00000182223 "Zygote arrest 1" Q86SH2 4 48490252-48494389 "Plasma proteins, Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 3.0;testis: 1.4" "Cell type enhanced" "Detected in some" "Early spermatids: 5.0;Inhibitory neurons: 1.9;Late spermatids: 8.6;Oligodendrocyte precursor cells: 3.0" "Not detected" "Not detected" "Region enhanced" "Detected in some" "midbrain: 3.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Region enhanced" "Detected in some" "midbrain: 2.1" NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (9.71e-2)" "unprognostic (2.58e-1)" "unprognostic (4.59e-3)" "unprognostic (2.47e-2)" "unprognostic (6.83e-2)" "unprognostic (2.41e-1)" "unprognostic (3.54e-1)" "unprognostic (1.08e-1)" "unprognostic (6.35e-2)" "unprognostic (6.32e-5)" "unprognostic (4.51e-1)" 0.0 0.0 0.1 0.0 0.4 0.4 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 3.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 1.0 0.0 1.1 0.0 3.0 0.2 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 ZBTB7C "ZBTB36, ZNF857C" ENSG00000184828 "Zinc finger and BTB domain containing 7C" A1YPR0 18 48026672-48410752 "Predicted intracellular proteins, Transcription factors" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 40.8" "Cell type enhanced" "Detected in many" "Astrocytes: 47.0;Basal squamous epithelial cells: 45.5;Distal enterocytes: 52.5;Excitatory neurons: 48.8;Gastric mucus-secreting cells: 49.5;Oligodendrocyte precursor cells: 51.3;Squamous epithelial cells: 96.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 4 "RT4: 42.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" "unprognostic (1.32e-1)" "unprognostic (1.11e-2)" "prognostic favorable (1.59e-4)" "unprognostic (2.83e-3)" "unprognostic (6.60e-2)" "unprognostic (2.91e-3)" "unprognostic (8.57e-2)" "unprognostic (2.63e-2)" "unprognostic (1.58e-2)" "unprognostic (1.47e-1)" "unprognostic (1.71e-2)" "unprognostic (1.54e-1)" "unprognostic (1.05e-2)" "unprognostic (2.71e-1)" "unprognostic (5.52e-3)" "unprognostic (3.85e-3)" "unprognostic (2.89e-2)" 5.3 11.2 7.8 2.0 3.9 0.4 6.1 3.6 5.4 8.4 0.0 14.5 1.8 1.7 17.2 40.8 14.0 3.4 1.6 4.6 8.1 1.9 0.9 4.5 0.6 7.6 6.6 6.5 1.0 5.2 1.8 3.7 4.3 3.2 13.4 6.3 14.7 3.9 1.7 22.4 2.9 2.1 5.0 9.2 13.8 9.2 14.7 0.3 16.7 1.6 3.8 11.0 19.5 4.8 0.0 0.0 1.5 1.2 0.2 0.4 0.8 0.0 0.0 0.1 0.0 0.3 0.2 0.0 0.5 0.0 1.7 2.7 0.1 0.4 0.2 0.3 1.3 0.2 3.2 0.1 0.0 0.0 0.4 0.1 0.7 0.2 0.4 0.0 0.0 1.2 0.0 0.1 0.6 0.7 1.7 0.5 0.5 8.6 0.0 0.1 0.0 9.7 1.3 42.7 5.4 6.9 0.6 0.3 0.0 1.4 0.9 0.0 0.0 0.1 0.6 0.5 0.0 0.1 0.2 0.0 2.7 0.1 0.2 1.0 0.1 0.1 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.5 0.2 0.0 0.0 7.8 3.9 3.6 5.4 4.6 8.1 7.6 6.6 4.3 5.0 14.7 4.8 0.5 6.4 1.5 47.0 0.1 6.1 5.3 11.6 45.5 1.2 6.0 8.4 3.1 12.8 9.5 1.8 0.0 13.7 0.1 52.5 0.0 1.0 9.6 4.8 1.8 2.9 4.8 0.0 48.8 4.0 0.8 3.4 49.5 6.7 0.0 1.0 0.0 0.6 1.5 1.7 7.0 30.8 6.1 2.1 0.8 4.4 3.7 0.4 3.6 22.5 0.1 1.0 0.0 51.3 2.1 1.2 14.6 12.0 0.0 7.5 3.5 0.0 7.6 2.5 13.1 8.8 11.9 0.9 0.9 96.9 8.8 12.6 0.2 6.6 18.3 13.7 ZC2HC1B "C6orf94, dJ468K18.5, FAM164B" ENSG00000118491 "Zinc finger C2HC-type containing 1B" Q5TFG8 6 143864436-143938343 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 48 "testis: 14.8" "Cell type enhanced" "Detected in some" "Astrocytes: 2.6;Early spermatids: 9.6;Excitatory neurons: 3.1;Inhibitory neurons: 5.7;Late spermatids: 5.5;Oligodendrocyte precursor cells: 4.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 14.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.6 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.6 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.3 5.5 0.0 0.0 1.8 1.0 0.0 0.0 0.0 4.5 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 ZC3H12A "FLJ23231, MCPIP1, Regnase-1" ENSG00000163874 "Zinc finger CCCH-type containing 12A" Q5D1E8 1 37474580-37484377 "Disease related genes, Predicted intracellular proteins" "Angiogenesis, Antiviral defense, Apoptosis, Differentiation, DNA damage, Host-virus interaction, Immunity, Inflammatory response, Neurogenesis, Stress response, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Endonuclease, Hydrolase, Nuclease, Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 136.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 300.7;Basal squamous epithelial cells: 242.4;Langerhans cells: 232.8;Squamous epithelial cells: 217.6;Suprabasal keratinocytes: 225.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+: 48.8;RT4: 61.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA032052, HPA032053" Uncertain Supported "Nucleoplasm,Cytoplasmic bodies" No No "Cluster 52: Eosinophils - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 15: RT4 - Unknown function" "Cluster 7: Non-specific - Mitochondria" "Cytoplasmic bodies" Nucleoplasm "HPA032052: AB_10603241, HPA032053: AB_2674128" "unprognostic (2.35e-2)" "unprognostic (6.09e-3)" "unprognostic (1.51e-2)" "prognostic favorable (9.67e-4)" "unprognostic (1.01e-1)" "unprognostic (1.88e-1)" "unprognostic (9.03e-2)" "unprognostic (4.66e-3)" "unprognostic (1.05e-1)" "unprognostic (9.69e-3)" "unprognostic (9.01e-2)" "unprognostic (1.82e-2)" "prognostic unfavorable (5.95e-5)" "unprognostic (5.17e-2)" "unprognostic (4.69e-2)" "unprognostic (1.68e-1)" "unprognostic (3.77e-2)" 28.9 28.0 2.4 17.3 2.3 136.3 15.1 3.6 4.1 9.1 2.7 16.3 14.1 6.6 4.6 45.4 14.3 36.0 12.1 2.5 3.8 15.7 23.3 40.0 13.6 4.1 3.7 6.0 12.4 2.5 9.2 3.7 4.1 29.5 7.9 0.3 22.9 5.2 10.8 51.5 20.1 5.7 3.0 15.5 23.5 5.2 3.7 5.7 6.5 3.2 15.5 39.0 21.4 2.8 7.8 5.5 0.6 3.5 2.7 4.0 6.2 5.5 48.8 3.5 4.5 6.1 17.2 8.7 22.8 5.3 37.8 16.8 2.2 35.4 2.0 17.8 3.2 2.3 20.9 9.7 3.9 4.6 3.5 8.6 17.8 30.0 5.3 7.9 3.9 4.4 4.3 14.1 3.1 9.4 3.5 8.3 4.2 10.4 4.8 5.2 2.2 5.1 8.8 61.2 1.6 1.1 11.0 17.4 1.3 5.3 6.0 5.1 4.1 10.3 5.7 7.7 8.5 11.2 4.5 6.6 23.5 9.7 2.0 1.2 1.4 4.0 3.1 1.4 3.3 3.1 1.3 1.9 1.7 3.9 0.7 1.5 5.6 3.5 1.2 1.5 2.0 1.7 2.4 2.3 3.6 4.1 2.5 3.8 4.1 3.7 4.1 3.0 3.7 2.8 19.1 16.0 36.2 1.6 56.9 195.9 149.8 300.7 242.4 0.4 93.6 69.8 4.2 61.5 117.6 11.0 0.0 3.7 78.1 71.5 0.0 79.5 16.9 67.6 20.8 32.2 63.9 0.4 0.1 73.9 10.0 41.0 66.3 102.2 42.6 5.0 5.3 11.4 9.7 0.0 0.1 77.3 69.2 10.5 232.8 2.7 0.9 71.2 48.0 1.0 14.0 0.9 9.2 0.5 0.9 55.4 73.2 1.2 52.1 127.9 59.5 0.6 58.4 4.5 6.6 52.7 36.1 1.6 1.3 217.6 225.2 11.8 76.6 9.5 62.2 81.9 ZC3H14 "FLJ11806, NY-REN-37, UKp68" ENSG00000100722 "Zinc finger CCCH-type containing 14" Q6PJT7 14 88562970-88627596 "Disease related genes, Human disease related genes, Predicted intracellular proteins" RNA-binding "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "testis: 173.6" "Cell type enhanced" "Detected in all" "Early spermatids: 1282.6;Late spermatids: 460.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049798, HPA053510" Enhanced Enhanced "Nucleoli,Nucleoli rim,Nuclear speckles" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 77: Retina - Visual perception" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 29: Early spermatids - Spermatogenesis" "Nuclear speckles" "Nucleoli, Nucleoli rim" "HPA049798: AB_2680888, HPA053510: AB_2682174" "unprognostic (5.80e-3)" "unprognostic (2.25e-1)" "unprognostic (1.35e-2)" "unprognostic (7.39e-2)" "unprognostic (2.06e-1)" "unprognostic (1.91e-1)" "unprognostic (6.47e-3)" "unprognostic (9.57e-2)" "unprognostic (7.21e-3)" "unprognostic (2.77e-3)" "unprognostic (4.83e-2)" "unprognostic (1.50e-2)" "prognostic favorable (7.08e-4)" "unprognostic (2.09e-1)" "unprognostic (8.23e-2)" "unprognostic (3.71e-1)" "unprognostic (4.25e-2)" 20.9 21.0 9.5 16.3 10.7 23.6 22.5 26.9 14.9 23.7 38.3 26.9 19.7 25.7 25.1 20.2 27.7 18.7 24.7 10.8 8.1 24.3 43.3 24.2 18.2 5.5 5.1 26.1 37.4 33.2 24.3 23.0 6.8 23.6 31.2 41.1 31.4 23.6 30.2 21.4 21.2 28.2 4.4 15.7 21.6 173.6 9.0 20.0 32.2 25.1 23.6 22.1 19.5 13.1 39.5 75.4 64.7 54.8 50.8 48.6 68.3 58.6 54.2 85.2 74.7 55.3 63.2 55.1 41.9 61.4 46.3 44.4 46.8 55.7 115.9 43.4 34.7 26.7 51.6 42.5 51.2 57.3 34.3 39.2 65.2 68.2 66.9 53.3 56.7 47.2 54.2 21.0 75.8 86.3 52.8 28.1 39.9 60.8 64.1 46.1 83.9 23.1 54.3 68.2 45.6 37.0 75.2 75.4 37.3 54.3 75.3 36.3 39.2 101.3 65.1 43.1 59.2 29.3 30.0 61.7 49.0 27.1 48.0 19.1 20.7 29.4 18.9 25.3 20.4 16.8 18.0 20.8 22.1 15.4 17.2 16.9 3.8 25.9 29.6 12.5 17.2 17.4 9.5 10.7 26.9 14.9 10.8 8.1 5.5 5.1 6.8 4.4 9.0 13.1 25.2 121.8 57.0 38.2 18.1 22.7 24.5 25.2 21.1 61.2 27.0 24.9 22.6 28.6 37.6 20.2 77.2 49.2 25.4 28.4 35.2 25.6 1282.6 53.0 46.6 28.7 31.8 17.1 88.8 23.0 27.4 30.5 20.9 34.3 45.6 51.8 24.3 38.1 20.3 65.6 65.5 31.4 34.6 14.9 16.3 460.1 39.4 19.6 5.4 34.7 20.0 33.6 18.6 64.3 62.9 22.0 16.4 47.4 18.6 26.0 27.4 32.4 53.0 78.9 13.1 46.6 35.4 217.9 81.5 23.0 19.7 40.6 20.1 39.2 32.8 16.3 ZCCHC13 "4930513O09RIK, Cnbp2, ZNF9L" ENSG00000187969 "Zinc finger CCHC-type containing 13" Q8WW36 X 74304180-74305034 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 229 "testis: 22.9" "Group enriched" "Detected in some" 80 "Early spermatids: 247.9;Late spermatids: 541.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA003382 Enhanced NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 31: Spermatids - Spermatogenesis" "HPA003382: AB_10967182" "unprognostic (1.61e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 247.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 541.7 2.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ZCCHC3 "C20orf99, dJ1103G7.7" ENSG00000247315 "Zinc finger CCHC-type containing 3" Q9NUD5 20 297570-300321 "Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042972 Approved Vesicles NA NA "Cluster 10: Basophils - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Vesicles "HPA042972: AB_10959663" "unprognostic (5.98e-3)" "unprognostic (1.38e-1)" "unprognostic (1.26e-2)" "unprognostic (1.01e-3)" "unprognostic (2.13e-1)" "unprognostic (3.04e-1)" "unprognostic (1.30e-2)" "unprognostic (1.90e-1)" "unprognostic (3.29e-1)" "unprognostic (6.55e-2)" "prognostic favorable (1.29e-4)" "unprognostic (4.30e-1)" "unprognostic (3.34e-3)" "unprognostic (6.33e-2)" "unprognostic (1.88e-1)" "unprognostic (3.67e-1)" "unprognostic (1.74e-2)" 9.9 11.3 14.5 11.7 14.1 17.8 8.4 15.8 16.8 10.8 15.9 8.9 9.8 11.2 12.5 6.8 13.0 8.3 9.8 13.5 19.5 10.9 10.0 8.6 17.7 14.8 15.7 18.2 10.8 11.7 10.9 20.1 15.1 9.2 7.5 8.5 8.8 10.7 9.8 6.1 11.4 8.1 13.2 15.4 10.3 9.6 17.7 23.1 8.9 12.6 15.7 9.8 6.3 14.2 24.0 18.4 56.7 28.4 18.3 18.6 33.6 14.7 16.2 16.2 16.7 28.4 14.0 21.8 9.6 9.5 16.7 32.6 29.2 16.5 15.3 11.8 26.8 44.1 9.3 90.0 21.2 50.9 11.7 18.2 19.2 9.9 11.7 16.8 26.2 24.4 55.7 21.5 12.7 10.6 38.8 62.1 50.7 23.3 19.6 56.5 27.1 27.7 14.4 15.2 23.5 34.7 17.5 34.9 46.8 24.2 16.0 93.8 11.4 16.6 16.3 6.8 17.8 39.1 53.9 42.3 6.0 32.4 16.3 2.5 1.2 2.2 1.6 0.7 1.5 1.7 1.4 1.3 0.9 2.1 1.6 1.6 0.4 1.1 0.5 2.1 1.4 0.8 14.5 14.1 15.8 16.8 13.5 19.5 14.8 15.7 15.1 13.2 17.7 14.2 17.3 0.0 9.1 8.8 12.6 15.8 22.7 3.5 11.4 26.9 16.1 12.8 7.6 17.2 4.9 9.2 8.4 22.4 22.3 13.0 3.9 5.9 0.7 22.6 28.0 16.4 21.0 17.9 6.8 5.4 13.4 14.5 8.2 14.9 0.0 16.1 19.2 10.2 11.0 37.0 8.0 16.2 4.1 9.8 9.7 2.1 17.4 11.5 12.4 8.4 11.0 19.6 8.2 7.1 12.3 5.2 10.3 10.5 8.9 16.3 12.2 6.8 8.9 22.1 6.6 14.2 12.3 5.8 7.6 7.2 5.7 20.7 11.1 21.2 13.3 16.0 ZCRB1 "MADP-1, MADP1, RBM36, SNRNP31, ZCCHC19" ENSG00000139168 "Zinc finger CCHC-type and RNA binding motif containing 1" Q8TBF4 12 42312086-42326257 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 219.4" "Cell type enhanced" "Detected in all" "Early spermatids: 889.2;Spermatocytes: 527.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 32: U-937 - Innate immune response" "Cluster 10: Non-specific - Unknown function" "unprognostic (8.75e-2)" "unprognostic (1.21e-1)" "unprognostic (1.49e-1)" "unprognostic (1.60e-2)" "unprognostic (9.28e-2)" "unprognostic (7.92e-3)" "prognostic unfavorable (5.33e-7)" "unprognostic (4.31e-2)" "unprognostic (1.85e-2)" "prognostic favorable (7.33e-4)" "unprognostic (3.11e-1)" "unprognostic (3.38e-1)" "prognostic unfavorable (1.37e-6)" "unprognostic (1.39e-2)" "unprognostic (4.33e-2)" "unprognostic (5.32e-3)" "unprognostic (9.44e-2)" 46.6 52.7 110.2 31.1 117.2 37.4 43.9 114.2 219.4 30.2 99.0 48.7 35.7 35.6 66.8 40.3 38.6 38.9 61.8 106.5 119.6 51.3 57.3 27.5 44.3 123.6 116.6 41.3 62.9 43.9 40.8 33.3 126.9 42.8 30.1 39.7 44.8 40.6 128.9 34.4 35.6 30.1 121.8 31.4 46.9 89.7 114.7 43.5 45.0 91.5 41.1 41.9 30.4 125.6 94.8 69.4 76.0 99.2 67.4 102.2 74.1 77.6 86.8 59.4 57.4 60.6 110.7 59.5 152.2 74.9 83.9 58.6 46.6 78.8 87.2 162.6 96.3 94.4 55.2 58.0 96.8 103.4 81.2 68.4 87.9 58.6 98.7 140.8 81.2 153.7 91.2 120.0 85.6 61.8 146.8 129.7 83.3 233.0 91.5 82.4 140.6 128.8 97.8 52.0 79.9 75.0 105.6 72.9 109.0 84.8 175.1 84.8 76.6 86.8 104.1 82.2 76.2 118.1 120.6 222.3 129.7 366.4 41.2 79.3 33.2 65.0 35.4 42.0 45.0 68.2 47.7 43.8 55.5 60.3 39.8 46.8 22.1 51.1 44.0 67.6 82.7 40.9 110.2 117.2 114.2 219.4 106.5 119.6 123.6 116.6 126.9 121.8 114.7 125.6 58.8 60.9 67.5 13.1 54.5 45.4 82.0 108.8 56.3 43.2 90.1 129.8 152.9 82.9 83.5 57.0 25.0 143.6 53.8 44.1 217.2 139.0 889.2 113.6 76.4 68.8 48.6 35.9 13.5 200.7 141.5 67.2 35.7 88.6 53.7 39.9 61.4 114.0 111.4 38.7 14.7 82.2 73.2 76.8 69.9 159.6 112.8 61.4 71.2 9.4 103.4 122.8 82.4 15.1 27.4 156.1 52.2 100.1 59.1 82.3 62.6 249.8 113.2 51.8 72.3 63.7 129.7 527.1 185.3 53.6 41.2 87.2 56.6 85.7 75.4 90.0 ZCWPW2 ZCW2 ENSG00000206559 "Zinc finger CW-type and PWWP domain containing 2" Q504Y3 3 28348721-28538122 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 9.9" "Cell type enhanced" "Detected in many" "Astrocytes: 35.6;Early spermatids: 95.0;Excitatory neurons: 33.7;Inhibitory neurons: 34.9;Oligodendrocyte precursor cells: 32.2;Oligodendrocytes: 31.7;Spermatocytes: 68.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in some" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA035035, HPA039839" Uncertain Approved "Nuclear speckles" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 23: Testis - Cell cycle regulation" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 66: Spermatocytes - Spermatogenesis" "Nuclear speckles" "HPA035035: AB_10602256, HPA039839: AB_2676708" "unprognostic (1.11e-1)" "unprognostic (4.18e-2)" "unprognostic (1.97e-1)" "unprognostic (1.34e-1)" "unprognostic (2.41e-1)" "unprognostic (4.59e-3)" "unprognostic (6.53e-2)" "unprognostic (6.09e-4)" "unprognostic (3.21e-1)" "unprognostic (2.70e-2)" "unprognostic (1.73e-3)" "unprognostic (1.12e-1)" "unprognostic (1.10e-4)" "unprognostic (1.06e-2)" "unprognostic (7.88e-2)" "unprognostic (1.40e-2)" "unprognostic (2.38e-2)" 1.5 1.7 1.8 0.9 1.5 0.8 1.8 1.6 1.9 1.4 0.2 1.4 1.2 2.1 2.1 1.3 1.0 2.0 2.7 1.7 1.1 1.6 1.2 1.3 1.2 0.8 1.0 2.4 1.9 1.5 1.2 1.2 1.0 2.2 1.1 1.6 2.3 1.1 6.2 1.9 0.9 1.0 0.8 1.1 1.8 9.9 1.2 0.6 2.5 4.5 1.0 0.8 0.8 1.6 0.3 0.2 0.8 0.3 1.2 2.8 1.2 1.1 0.8 0.3 0.3 0.2 0.9 0.7 0.5 0.6 0.8 0.4 0.2 0.2 0.3 0.4 0.4 0.3 1.1 0.3 0.6 0.5 0.6 1.2 0.5 0.3 0.5 1.3 0.5 1.5 0.3 1.0 1.5 0.3 0.2 0.6 0.3 0.1 1.1 0.3 0.3 0.6 1.2 0.1 0.3 0.9 0.2 0.4 0.7 0.8 0.4 2.6 1.0 0.8 0.4 0.7 0.6 0.3 0.2 0.3 2.8 0.5 1.0 1.0 0.7 1.1 0.3 0.7 0.2 0.1 0.3 0.2 0.3 0.2 0.5 0.7 1.0 0.2 0.2 0.4 0.3 0.2 1.8 1.5 1.6 1.9 1.7 1.1 0.8 1.0 1.0 0.8 1.2 1.6 1.6 0.0 2.0 35.6 0.4 0.6 2.7 3.7 1.2 3.0 1.6 2.7 13.6 0.0 4.3 0.0 0.0 2.4 0.1 0.4 5.9 0.5 95.0 1.2 1.2 1.0 1.2 0.0 33.7 0.9 1.4 4.3 0.0 0.6 2.5 0.8 1.4 0.5 1.3 3.3 34.9 1.9 8.2 0.6 0.7 17.7 4.7 1.3 0.0 13.1 0.7 3.7 1.0 32.2 31.7 0.6 0.3 4.9 0.3 1.1 0.6 2.6 1.7 2.0 0.0 4.4 4.5 68.7 5.8 1.1 1.6 1.2 0.6 1.3 0.7 1.3 ZDHHC4 "FLJ10479, ZNF374" ENSG00000136247 "Zinc finger DHHC-type palmitoyltransferase 4" Q9NPG8 7 6577434-6589374 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA032124 Approved NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "HPA032124: AB_10610699" "unprognostic (1.07e-1)" "prognostic unfavorable (9.35e-4)" "unprognostic (6.82e-2)" "unprognostic (8.36e-2)" "unprognostic (3.66e-1)" "prognostic unfavorable (3.95e-6)" "unprognostic (9.80e-2)" "unprognostic (1.40e-1)" "unprognostic (2.37e-1)" "unprognostic (4.60e-2)" "unprognostic (1.52e-1)" "unprognostic (1.43e-1)" "prognostic favorable (1.18e-7)" "unprognostic (8.75e-2)" "unprognostic (9.41e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (8.94e-4)" 25.9 31.0 17.5 16.2 19.4 18.8 24.3 19.4 18.8 24.4 21.1 38.2 19.1 28.0 34.2 19.5 31.0 23.3 26.5 17.8 21.1 33.6 35.7 21.9 20.6 19.5 20.9 27.6 37.9 33.0 23.9 18.5 20.5 25.3 20.8 19.3 32.2 25.5 54.5 13.5 22.5 24.6 19.1 17.9 32.9 33.8 20.9 18.6 36.8 43.7 19.4 29.2 18.7 19.6 50.7 35.0 11.7 68.8 60.8 41.4 52.4 26.2 6.5 31.2 44.3 44.3 69.7 29.9 40.1 51.3 66.2 44.2 40.8 25.7 33.2 16.8 24.0 31.4 37.8 48.6 47.8 39.8 36.6 45.2 37.6 24.1 0.0 40.8 27.9 51.8 72.4 40.3 43.5 59.2 22.1 39.6 59.4 45.0 28.1 29.4 57.5 40.3 25.9 43.7 26.9 68.7 35.5 11.8 51.7 60.4 43.1 45.8 18.7 40.6 54.9 39.2 39.3 62.1 58.7 66.7 21.6 50.0 56.5 56.3 25.0 44.8 24.1 31.9 24.8 38.8 25.1 27.3 28.1 36.0 31.4 31.1 2.9 28.7 26.5 113.9 24.5 29.3 17.5 19.4 19.4 18.8 17.8 21.1 19.5 20.9 20.5 19.1 20.9 19.6 11.7 38.5 20.1 2.9 23.3 11.3 46.5 63.4 24.5 30.2 42.1 34.7 4.4 57.2 42.4 35.0 10.4 69.0 46.1 12.1 86.1 60.5 3.0 24.1 22.1 14.3 32.4 26.5 4.6 66.4 69.4 26.0 20.9 20.3 10.2 25.9 25.0 47.3 55.3 21.9 5.4 21.2 42.7 36.5 18.2 3.5 18.0 24.8 21.4 2.8 35.3 71.8 28.8 5.0 6.7 54.6 21.4 32.7 34.2 39.5 27.2 71.9 32.5 24.6 13.1 20.9 25.6 70.2 69.7 19.2 9.2 48.8 19.0 40.6 27.5 39.5 ZDHHC5 "DHHC5, KIAA1748, ZNF375" ENSG00000156599 "Zinc finger DHHC-type palmitoyltransferase 5" Q9C0B5 11 57667747-57701182 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014670 Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 15: RT4 - Unknown function" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane" Nucleoplasm "HPA014670: AB_2257442" "unprognostic (1.34e-1)" "unprognostic (3.47e-2)" "unprognostic (2.51e-1)" "unprognostic (2.29e-1)" "unprognostic (5.32e-2)" "unprognostic (1.70e-2)" "unprognostic (9.82e-3)" "unprognostic (1.74e-3)" "unprognostic (4.36e-2)" "unprognostic (9.78e-2)" "prognostic unfavorable (6.74e-5)" "unprognostic (1.76e-1)" "unprognostic (4.72e-3)" "unprognostic (2.16e-1)" "unprognostic (6.80e-2)" "unprognostic (2.06e-2)" "unprognostic (1.74e-3)" 29.0 21.7 8.3 27.2 7.8 29.2 25.8 8.3 9.5 27.0 11.0 36.4 29.6 22.3 24.1 60.9 25.0 27.9 27.9 7.5 9.2 28.2 36.7 29.0 24.4 8.5 8.9 20.7 31.6 45.3 12.6 36.7 8.7 28.0 34.4 35.9 35.0 26.7 40.9 45.2 31.0 29.0 6.9 25.5 30.2 36.2 10.9 30.6 36.9 45.5 35.0 42.3 28.7 8.9 80.3 86.2 33.7 34.7 74.9 57.4 64.9 72.8 89.8 61.8 46.3 52.3 97.0 53.4 91.9 89.5 53.1 110.1 53.6 88.9 55.4 66.5 24.4 45.8 40.1 49.3 81.5 85.9 73.7 81.3 79.3 88.8 92.9 51.1 71.0 45.6 61.5 66.2 79.7 48.4 49.1 29.3 41.1 61.0 52.2 47.8 66.6 67.1 74.8 115.2 25.3 30.7 67.6 77.0 78.5 45.4 81.9 52.6 80.7 76.5 40.7 82.9 52.2 48.2 63.0 45.9 59.1 44.4 68.0 11.6 5.2 7.1 6.9 6.8 8.3 5.8 6.7 6.0 5.4 5.7 6.7 6.9 6.9 5.0 8.1 9.0 7.0 6.8 8.3 7.8 8.3 9.5 7.5 9.2 8.5 8.9 8.7 6.9 10.9 8.9 28.8 16.0 10.5 14.7 13.4 16.2 12.7 13.7 16.5 21.4 20.4 15.2 21.6 12.8 19.8 12.9 37.5 10.1 20.3 41.3 3.9 14.4 21.3 19.9 22.1 17.1 11.5 10.8 16.4 18.2 9.9 15.5 15.8 35.5 19.7 24.9 16.1 15.1 13.0 13.5 17.9 17.5 18.3 16.3 10.2 9.8 11.8 18.4 1.8 14.0 16.0 14.0 17.5 17.6 14.7 26.0 20.8 7.5 12.4 15.1 22.9 11.4 17.4 47.7 0.0 18.4 18.5 13.3 7.1 31.5 19.9 18.6 15.9 16.8 19.7 20.5 ZER1 "C9orf60, Hzyg, ZYG, ZYG11BL" ENSG00000160445 "Zyg-11 related cell cycle regulator" Q7Z7L7 9 128729786-128772414 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 67.7;Inhibitory neurons: 61.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048464 Approved Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA048464: AB_2756306" "unprognostic (1.37e-1)" "prognostic favorable (1.18e-6)" "unprognostic (9.11e-3)" "unprognostic (2.36e-2)" "unprognostic (7.46e-2)" "unprognostic (9.35e-2)" "unprognostic (2.18e-1)" "unprognostic (4.81e-3)" "unprognostic (3.65e-1)" "unprognostic (4.90e-3)" "unprognostic (6.65e-3)" "unprognostic (1.69e-1)" "prognostic favorable (5.15e-11)" "unprognostic (5.77e-2)" "unprognostic (1.31e-1)" "unprognostic (7.71e-2)" "unprognostic (1.14e-1)" 24.3 31.0 57.4 12.4 56.4 17.1 23.8 28.3 72.8 26.7 23.2 38.9 33.3 29.8 13.1 28.6 25.9 17.4 44.1 59.7 48.2 26.5 22.9 19.9 13.9 44.6 40.1 28.1 26.6 31.9 33.5 15.9 44.8 31.7 13.0 17.3 27.4 24.7 72.0 33.8 31.5 16.4 28.5 19.6 26.9 36.6 43.8 19.2 26.5 43.6 11.3 31.0 24.7 46.1 17.3 19.1 12.4 17.0 36.4 24.9 34.3 16.7 28.4 22.6 18.1 17.3 19.6 10.6 18.1 29.3 16.9 37.1 13.8 24.8 9.5 21.2 17.7 7.0 34.2 12.4 28.3 11.1 20.1 31.1 36.6 22.9 16.1 30.6 19.5 21.2 13.7 22.9 15.5 65.9 20.9 12.5 12.3 24.6 24.4 18.6 15.6 41.4 16.8 23.4 23.7 17.9 26.7 35.4 18.9 14.4 52.0 12.7 22.2 18.4 7.8 23.5 10.2 28.7 29.3 8.6 27.2 6.6 13.5 11.5 3.2 8.8 4.4 4.7 6.0 3.0 4.7 5.7 3.3 3.8 4.9 4.7 13.6 5.1 5.2 4.9 4.7 5.0 57.4 56.4 28.3 72.8 59.7 48.2 44.6 40.1 44.8 28.5 43.8 46.1 10.7 12.8 16.8 33.0 8.0 2.8 2.9 5.2 6.2 20.2 13.0 12.6 22.6 4.3 4.7 5.5 14.6 4.8 4.8 41.7 1.9 5.8 7.1 15.2 8.6 9.0 7.2 17.9 67.7 9.6 2.5 8.6 13.7 11.8 10.2 12.0 7.1 13.0 6.2 21.9 61.2 15.0 2.0 4.4 1.0 2.4 11.1 5.7 8.8 16.9 9.5 9.8 6.2 23.1 48.9 7.1 23.2 10.5 8.7 6.4 25.4 13.8 13.5 13.4 13.1 9.2 9.1 10.6 3.5 8.0 5.8 8.5 7.1 16.0 9.6 3.4 ZFAND3 "FLJ13222, TEX27" ENSG00000156639 "Zinc finger AN1-type containing 3" Q9H8U3 6 37819727-38154624 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Early spermatids: 821.8;Late spermatids: 3021.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016755 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Vesicles" "HPA016755: AB_1859011" "unprognostic (3.32e-1)" "unprognostic (3.04e-2)" "unprognostic (1.36e-1)" "unprognostic (2.89e-2)" "unprognostic (1.60e-1)" "unprognostic (1.14e-1)" "unprognostic (9.24e-2)" "unprognostic (1.37e-1)" "unprognostic (1.07e-1)" "unprognostic (1.36e-2)" "unprognostic (9.30e-2)" "unprognostic (1.48e-2)" "unprognostic (9.60e-3)" "unprognostic (1.01e-1)" "unprognostic (2.94e-1)" "unprognostic (7.41e-2)" "unprognostic (4.33e-1)" 44.2 42.3 36.6 31.7 38.0 42.6 36.4 36.8 36.4 42.6 33.2 50.3 39.3 41.2 35.3 37.4 33.4 36.3 51.1 37.0 41.4 47.7 53.3 37.8 28.1 46.2 40.8 32.3 39.0 56.6 33.8 48.8 41.5 35.3 32.1 39.4 32.8 46.1 137.8 33.8 39.5 46.9 39.2 31.6 42.0 113.0 38.2 39.7 52.0 67.3 29.3 49.3 31.2 42.9 59.1 33.8 116.8 82.8 72.4 75.9 42.5 88.6 115.6 87.3 92.8 68.4 33.4 24.6 71.8 106.8 96.2 39.5 48.3 73.4 122.3 102.2 30.6 75.6 17.3 65.3 171.0 29.5 59.4 96.1 93.7 91.7 157.0 101.6 76.8 56.9 37.3 48.1 68.4 50.6 50.2 27.0 33.4 84.5 38.4 52.4 48.4 29.6 79.5 94.0 74.2 63.2 54.6 43.6 151.5 98.1 70.2 61.5 81.5 87.2 66.2 47.5 58.8 47.3 47.7 74.2 32.4 47.1 91.9 0.5 1.7 6.1 1.5 1.7 1.1 1.3 1.1 1.2 0.9 1.9 0.9 1.5 6.0 1.6 1.3 2.9 1.5 0.9 36.6 38.0 36.8 36.4 37.0 41.4 46.2 40.8 41.5 39.2 38.2 42.9 25.4 22.4 11.5 241.0 27.0 27.3 30.9 20.0 52.9 25.8 19.8 19.4 23.0 25.8 11.6 47.8 22.9 35.0 23.2 55.2 74.3 27.3 821.8 25.4 26.6 28.1 16.2 22.5 332.7 29.3 33.1 27.2 31.6 33.2 5.1 33.9 27.5 48.8 33.8 30.3 262.9 30.5 6.1 43.7 44.3 3021.1 38.8 49.2 14.2 283.9 32.9 47.4 34.0 276.0 316.4 38.9 29.1 55.3 28.3 52.3 57.6 38.2 17.2 21.6 32.9 32.9 31.2 63.5 54.1 41.3 30.1 86.1 31.2 21.1 21.5 61.2 ZFAT "KIAA1485, ZFAT1, ZNF406" ENSG00000066827 "Zinc finger and AT-hook domain containing" Q9P243 8 134477788-134713049 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 31.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 74.5;dendritic cells: 35.6;Early spermatids: 49.3;Late spermatids: 53.0;Syncytiotrophoblasts: 126.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in some" 24 "plasmacytoid DC: 34.5" "Lineage enriched" "Detected in many" 24 "dendritic cells: 34.5" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020989, HPA063592" Enhanced Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 2: Karpas-707 - Immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Nuclear bodies" Nucleoplasm "HPA020989: AB_2670552, HPA063592: AB_2685051" "unprognostic (2.00e-1)" "unprognostic (1.45e-1)" "unprognostic (4.62e-3)" "unprognostic (5.91e-3)" "unprognostic (2.45e-1)" "unprognostic (5.12e-2)" "unprognostic (1.31e-4)" "unprognostic (6.27e-2)" "unprognostic (2.68e-2)" "unprognostic (1.28e-1)" "unprognostic (2.43e-2)" "unprognostic (1.13e-1)" "unprognostic (1.90e-2)" "unprognostic (1.80e-1)" "unprognostic (2.24e-1)" "unprognostic (7.08e-3)" "unprognostic (1.33e-1)" 2.2 1.4 0.8 2.8 0.9 1.2 2.1 0.5 1.4 1.8 1.7 4.7 2.3 2.5 2.0 2.6 2.0 1.2 2.2 1.0 0.9 9.7 1.5 2.2 3.7 1.3 0.6 2.1 2.3 2.7 1.5 31.1 0.8 2.2 1.7 2.7 1.8 2.1 7.5 1.9 2.1 2.6 0.5 2.5 1.9 2.3 0.7 3.2 1.6 4.3 2.9 2.8 1.8 0.7 4.1 6.5 2.3 2.9 4.4 4.3 2.1 4.4 3.8 3.9 4.0 4.5 5.2 4.7 3.8 4.6 2.3 3.2 4.7 5.6 5.1 3.9 6.0 8.7 5.7 3.3 3.4 4.9 4.3 3.5 2.8 4.3 5.7 3.6 4.9 1.7 3.4 8.4 3.4 5.6 5.1 0.8 3.2 4.2 3.9 3.1 3.0 2.0 3.8 6.2 2.8 2.1 4.5 3.4 3.7 2.6 2.8 4.6 5.4 2.3 3.4 3.3 5.0 3.0 4.4 4.5 2.8 3.6 4.9 1.1 0.6 1.4 0.4 0.8 0.4 0.9 0.4 0.7 0.5 1.1 0.6 0.4 1.0 0.1 0.5 34.5 0.3 0.9 0.8 0.9 0.5 1.4 1.0 0.9 1.3 0.6 0.8 0.5 0.7 0.7 3.5 3.2 3.3 14.4 7.0 1.5 1.2 1.0 1.8 5.3 4.0 1.4 2.0 1.5 3.1 1.8 4.2 74.5 35.6 1.5 0.0 2.1 49.3 2.6 5.0 2.8 0.0 0.8 24.4 1.5 17.2 2.7 3.6 3.1 2.5 2.9 0.7 1.4 8.4 1.7 18.9 1.4 0.0 3.8 2.1 53.0 3.4 4.2 8.8 14.0 3.5 2.1 4.1 9.5 12.6 3.3 0.5 2.6 17.0 1.6 1.1 12.2 1.1 6.0 0.0 3.7 2.5 2.9 5.5 1.9 1.7 126.7 3.6 3.2 1.3 1.5 ZFP91 "PZF, ZNF757" ENSG00000186660 "ZFP91 zinc finger protein, atypical E3 ubiquitin ligase" Q96JP5 11 58579063-58621550 "Enzymes, Predicted intracellular proteins, Transcription factors" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 243.7;Late spermatids: 179.3;Spermatocytes: 140.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA024037, CAB025417, HPA065325" Approved Supported Nucleoplasm,Nucleoli NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 23: Testis - Cell cycle regulation" "Cluster 18: U-2197 - ECM organization" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nucleoli" "CAB025417: , HPA024037: AB_1859051, HPA065325: AB_2685468" "unprognostic (6.10e-2)" "unprognostic (5.01e-2)" "unprognostic (3.33e-3)" "unprognostic (9.19e-2)" "unprognostic (1.24e-1)" "unprognostic (2.33e-1)" "unprognostic (2.33e-2)" "unprognostic (3.37e-2)" "unprognostic (1.06e-1)" "unprognostic (2.36e-2)" "prognostic unfavorable (3.74e-6)" "unprognostic (3.16e-1)" "unprognostic (1.75e-3)" "unprognostic (3.12e-2)" "unprognostic (2.61e-1)" "unprognostic (2.23e-1)" "unprognostic (2.00e-3)" 25.0 22.0 27.8 23.0 32.3 59.2 21.9 28.0 33.4 22.0 16.0 28.9 25.9 22.4 17.6 24.4 19.9 21.5 29.8 22.9 26.9 25.1 30.7 21.3 24.8 26.5 28.8 20.2 22.8 29.8 15.3 20.3 27.1 19.3 33.5 29.8 20.2 22.6 53.2 25.7 29.0 24.4 28.8 24.3 21.1 86.4 28.4 36.7 25.9 45.3 26.2 27.5 20.4 32.8 65.4 36.3 42.0 43.3 39.6 47.5 23.1 52.3 98.3 59.6 50.7 19.9 67.1 77.5 50.6 66.9 59.4 56.7 43.2 56.0 77.9 41.3 24.3 51.2 36.5 21.9 44.9 65.3 80.9 41.8 53.8 83.9 97.3 49.4 60.0 51.5 51.4 71.4 77.7 21.7 56.8 36.1 22.2 37.6 35.4 43.4 71.0 51.8 43.8 60.9 45.1 35.9 67.2 61.0 86.8 22.7 68.2 48.5 67.8 74.8 51.4 114.0 59.3 41.0 32.3 62.9 66.2 36.1 78.1 1.3 1.4 1.0 1.5 1.2 0.8 1.3 0.9 0.9 1.4 1.1 0.9 1.2 1.5 1.0 1.3 2.0 0.8 0.8 27.8 32.3 28.0 33.4 22.9 26.9 26.5 28.8 27.1 28.8 28.4 32.8 24.6 25.6 33.6 0.0 29.1 60.2 26.1 20.6 44.3 31.9 25.4 17.9 45.7 38.6 20.6 18.4 16.7 12.1 31.7 46.2 13.7 23.7 243.7 30.1 33.7 28.8 25.2 46.7 0.0 31.2 11.4 31.3 23.9 40.9 50.6 32.5 27.5 51.3 16.6 35.3 0.0 27.6 12.2 45.3 55.9 179.3 30.7 36.5 23.2 0.0 36.4 21.1 25.7 0.0 0.0 29.5 18.6 27.1 26.2 35.0 34.6 26.7 24.2 22.4 19.7 34.7 27.6 140.9 41.1 53.7 66.5 13.8 24.2 17.9 39.1 43.4 ZFYVE27 "FLJ32919, SPG33" ENSG00000155256 "Zinc finger FYVE-type containing 27" Q5T4F4 10 97737121-97760907 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037523, HPA069876" Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 9: Photoreceptor cells - Phototransduction" "Nucleoplasm, Vesicles" Cytosol "HPA037523: AB_10672351, HPA069876: AB_2686218" "unprognostic (2.21e-1)" "unprognostic (1.91e-1)" "prognostic unfavorable (6.91e-4)" "unprognostic (3.12e-1)" "unprognostic (3.42e-2)" "unprognostic (9.76e-2)" "unprognostic (1.22e-1)" "unprognostic (2.30e-2)" "unprognostic (2.48e-2)" "unprognostic (7.15e-2)" "unprognostic (2.05e-3)" "unprognostic (5.24e-2)" "unprognostic (3.38e-3)" "prognostic favorable (7.54e-4)" "unprognostic (4.18e-2)" "unprognostic (1.26e-2)" "prognostic favorable (7.80e-4)" 14.4 27.9 33.1 12.9 32.1 23.2 15.8 29.2 35.9 20.6 34.8 25.6 24.8 16.5 22.9 16.5 20.3 12.1 17.8 35.5 33.6 28.3 32.6 17.7 16.1 32.6 31.4 25.9 23.7 19.2 38.3 9.5 33.2 22.0 16.3 28.4 18.9 10.3 12.8 18.2 30.6 8.5 29.1 29.1 19.8 23.0 33.5 12.7 20.4 5.9 13.1 16.8 17.0 32.4 17.7 21.4 12.6 28.1 14.1 9.8 17.2 17.7 18.5 20.3 19.7 19.1 35.9 27.2 19.8 12.8 25.9 38.8 18.4 17.2 10.6 28.3 18.6 12.9 23.1 18.1 18.1 20.9 24.9 16.0 20.4 19.9 15.2 32.4 11.5 22.5 19.6 17.9 15.3 13.8 16.9 39.4 10.3 15.3 16.4 19.2 12.7 13.0 19.5 10.8 10.1 19.7 11.9 9.9 47.2 11.5 21.8 20.5 12.4 10.2 11.9 15.6 34.2 20.6 18.6 14.3 25.3 26.5 11.9 4.8 5.8 9.3 9.6 6.2 8.2 7.1 6.6 7.9 5.4 6.7 7.5 8.3 8.2 6.8 9.2 5.6 9.5 8.3 33.1 32.1 29.2 35.9 35.5 33.6 32.6 31.4 33.2 29.1 33.5 32.4 10.0 3.2 11.4 14.0 22.1 8.2 12.8 11.3 18.8 29.9 11.1 8.9 7.2 14.3 9.7 14.7 58.4 7.4 21.2 33.9 7.9 14.9 5.2 14.3 7.8 11.0 20.3 14.3 33.6 16.0 5.7 10.1 19.4 11.4 14.0 17.3 10.8 10.9 8.2 37.0 35.2 15.6 14.2 8.8 5.7 1.5 9.6 11.0 10.6 16.9 11.2 14.8 15.5 12.5 20.2 13.9 26.1 9.1 13.4 13.8 35.5 8.6 16.6 43.7 19.7 6.7 9.9 8.9 7.6 10.4 5.5 13.5 17.9 10.9 14.7 17.7 ZG16 "hZG16, JCLN, JCLN1, ZG16A" ENSG00000174992 "Zymogen granule protein 16" O60844 16 29778256-29782973 "Predicted secreted proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 22 "intestine: 479.5" "Cell type enriched" "Detected in some" 10 "Intestinal goblet cells: 20216.0" "Cancer enriched" "Detected in some" 6 "colorectal cancer: 21.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SK-BR-3: 2.3" "Not detected" "Not detected" "HPA052066, HPA052512" Enhanced "Secreted to digestive system" NA NA 1300000 "Cluster 37: Intestine - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 27: Mucus-secreting cells - Mucin production" "HPA052066: AB_2681716, HPA052512: AB_2681857" "unprognostic (1.64e-2)" "unprognostic (2.05e-1)" "unprognostic (2.60e-3)" "unprognostic (8.20e-2)" "unprognostic (3.50e-2)" "unprognostic (1.93e-2)" "unprognostic (5.14e-2)" "unprognostic (1.65e-1)" "unprognostic (7.77e-2)" "unprognostic (3.27e-1)" "unprognostic (2.56e-2)" "unprognostic (9.99e-2)" "unprognostic (1.22e-1)" "unprognostic (2.42e-1)" 0.5 0.0 0.0 7.8 0.2 0.1 0.7 0.1 0.1 0.0 0.0 362.9 57.8 0.6 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.4 22.2 0.0 0.2 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.1 479.5 0.1 0.0 0.5 0.0 0.1 136.9 12.9 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 2.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.3 0.4 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.6 0.0 1107.2 0.0 0.0 0.0 0.1 0.0 0.1 145.5 0.0 0.1 11.9 0.0 0.1 0.0 0.2 40.1 0.0 0.4 44.6 0.0 0.0 0.1 20216.0 0.0 0.8 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 484.8 0.0 0.0 0.2 1950.6 1.6 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.5 7.1 0.0 306.7 0.3 ZGRF1 "C4orf21, FLJ11331" ENSG00000138658 "Zinc finger GRF-type containing 1" Q86YA3 4 112539333-112636995 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 7.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 18.0;Microglial cells: 17.8;Oligodendrocytes: 27.5;Spermatocytes: 22.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA030704, HPA030706" Uncertain Approved Cytosol NA Yes "Cluster 7: Monocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA030704: AB_2673577, HPA030706: AB_10601784" "unprognostic (8.48e-2)" "unprognostic (6.17e-2)" "unprognostic (9.51e-2)" "unprognostic (1.53e-1)" "unprognostic (1.10e-1)" "unprognostic (1.84e-3)" "unprognostic (5.83e-3)" "unprognostic (1.45e-1)" "unprognostic (5.89e-4)" "unprognostic (4.74e-2)" "unprognostic (4.30e-2)" "unprognostic (3.72e-3)" "unprognostic (7.60e-10)" "unprognostic (3.45e-2)" "unprognostic (2.93e-1)" "unprognostic (1.15e-1)" "unprognostic (2.02e-4)" 1.0 0.7 0.9 2.0 1.4 7.8 1.3 2.2 1.5 0.9 0.1 1.1 1.2 1.2 0.3 1.0 0.8 0.5 0.7 0.8 0.7 0.5 0.6 0.9 2.5 1.3 0.9 1.1 0.7 0.3 1.3 1.7 1.3 0.9 1.4 4.3 0.9 0.4 1.2 1.4 1.5 0.9 1.0 1.8 0.9 3.6 1.0 5.2 0.8 0.6 2.9 0.7 0.8 2.1 5.0 3.6 12.1 8.6 0.9 1.6 4.7 8.8 3.7 8.7 7.8 6.9 7.3 13.2 2.5 2.7 3.6 4.0 12.7 4.7 10.0 7.3 3.1 8.3 5.8 2.1 0.4 18.5 5.3 0.8 0.6 11.0 3.0 1.2 3.5 13.6 12.0 14.3 6.0 8.2 25.0 6.7 6.3 5.2 4.2 13.8 18.1 4.5 1.5 4.4 5.6 9.5 3.9 5.3 1.7 8.8 2.5 5.4 4.2 10.9 10.6 5.9 7.1 5.5 10.1 17.0 4.9 6.3 6.3 0.0 0.1 0.3 0.2 0.7 0.1 0.3 0.1 0.0 0.0 0.5 0.4 0.4 0.2 0.2 0.1 0.7 0.2 0.1 0.9 1.4 2.2 1.5 0.8 0.7 1.3 0.9 1.3 1.0 1.0 2.1 3.3 0.0 1.3 10.4 5.4 0.0 1.3 0.0 0.6 10.4 2.1 1.7 2.4 0.0 3.7 1.8 8.4 3.5 10.4 2.1 0.0 1.0 2.9 1.8 3.5 1.9 1.2 11.1 18.0 0.5 2.7 2.3 4.6 2.8 2.5 12.2 1.1 0.6 1.8 5.0 14.5 1.8 0.0 1.6 0.0 2.8 0.6 4.1 0.0 17.8 1.3 1.6 6.2 17.6 27.5 0.6 1.4 2.2 10.5 0.8 0.7 0.3 0.7 17.6 0.0 3.1 2.7 22.1 15.6 3.6 0.0 0.8 5.0 2.2 2.5 0.9 ZKSCAN4 "FLJ32136, P1P373C6, p373c6.1, ZNF307, ZNF427, ZSCAN36" ENSG00000187626 "Zinc finger with KRAB and SCAN domains 4" Q969J2 6 28241697-28252269 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 27.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA009637 Approved Supported Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 71: Testis - DNA repair" "Cluster 32: U-937 - Innate immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "HPA009637: AB_2668244" "unprognostic (4.29e-2)" "unprognostic (2.88e-1)" "unprognostic (1.04e-1)" "unprognostic (5.01e-2)" "unprognostic (4.23e-3)" "unprognostic (3.77e-2)" "prognostic unfavorable (1.90e-6)" "prognostic favorable (5.04e-4)" "unprognostic (8.73e-3)" "unprognostic (1.80e-2)" "unprognostic (7.20e-2)" "unprognostic (5.13e-2)" "unprognostic (2.13e-2)" "unprognostic (1.62e-1)" "unprognostic (6.07e-2)" "unprognostic (9.70e-2)" "unprognostic (7.36e-3)" 2.7 2.7 1.6 1.9 1.6 1.0 2.6 2.7 2.0 3.5 1.6 2.9 2.0 3.5 2.0 2.5 2.6 1.4 2.2 1.6 1.6 2.7 3.0 2.0 3.4 1.6 1.5 3.2 2.3 2.3 2.1 2.1 1.7 2.7 2.0 2.2 2.9 1.9 1.6 2.9 3.6 1.5 1.5 8.6 2.5 8.9 1.6 4.1 2.4 1.6 3.3 2.9 2.8 1.9 1.4 1.0 2.8 4.7 3.2 3.1 2.6 1.8 2.9 2.6 2.9 1.6 1.2 3.9 3.3 2.1 1.6 1.6 2.9 2.3 2.7 1.8 3.1 3.3 2.5 2.2 2.2 6.6 2.9 3.4 2.8 2.3 2.3 3.3 2.7 3.4 3.1 0.8 2.2 1.4 4.4 6.9 2.2 0.6 1.9 3.4 3.9 2.5 1.6 1.1 4.3 3.1 1.5 2.0 3.3 2.5 1.7 3.0 2.2 2.9 1.7 1.7 1.8 2.5 2.6 1.8 1.0 6.5 1.7 2.8 1.9 2.2 1.9 1.6 2.2 1.8 1.8 1.8 3.2 1.7 2.7 2.6 2.5 2.4 1.9 4.2 1.8 1.4 1.6 1.6 2.7 2.0 1.6 1.6 1.6 1.5 1.7 1.5 1.6 1.9 1.7 0.0 0.5 2.6 2.2 0.4 0.5 1.0 1.2 1.1 1.5 1.4 1.3 2.8 2.7 1.8 2.1 3.9 3.9 2.2 0.0 2.7 9.8 1.3 3.2 2.2 3.5 3.8 7.9 2.0 2.8 2.5 3.1 1.4 2.5 4.2 2.5 1.0 4.5 1.7 6.5 1.5 0.0 10.7 1.8 6.9 2.8 2.9 1.8 7.5 2.6 2.2 3.1 2.5 3.9 1.7 4.9 3.8 1.3 0.4 2.3 1.7 0.4 1.7 0.0 1.6 1.6 27.4 2.4 1.6 0.3 1.1 2.1 3.5 2.3 0.3 ZMYND8 "PRKCBP1, RACK7" ENSG00000101040 "Zinc finger MYND-type containing 8" Q9ULU4 20 47209214-47356889 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020949 Approved Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 44: Endometrium - Transcription" Nucleoplasm "Golgi apparatus" "HPA020949: AB_1857223" "prognostic unfavorable (2.56e-4)" "unprognostic (5.09e-2)" "unprognostic (5.84e-2)" "unprognostic (3.30e-1)" "unprognostic (2.12e-1)" "unprognostic (1.67e-1)" "prognostic unfavorable (2.62e-4)" "unprognostic (2.10e-1)" "unprognostic (2.60e-1)" "unprognostic (1.50e-1)" "unprognostic (8.64e-2)" "unprognostic (3.62e-1)" "prognostic unfavorable (7.06e-5)" "unprognostic (3.59e-2)" "unprognostic (7.50e-2)" "unprognostic (2.53e-1)" "unprognostic (1.47e-3)" 13.1 32.7 25.4 10.5 21.3 26.0 14.7 26.2 36.2 11.9 47.8 14.1 11.0 9.8 33.3 16.0 15.9 12.3 12.5 35.5 29.5 18.5 10.9 11.1 12.8 30.5 22.9 13.6 12.3 11.6 25.9 11.8 33.0 11.8 14.5 20.1 14.6 14.6 15.3 19.9 16.2 8.7 9.4 18.3 20.0 14.2 25.2 14.6 11.0 11.0 12.8 14.5 14.9 37.3 27.6 17.2 90.5 36.6 15.2 21.3 59.4 21.7 17.8 22.3 22.8 107.7 26.0 26.5 34.4 16.3 27.1 18.7 39.4 96.0 33.3 11.4 14.9 110.4 6.3 95.9 55.4 11.9 55.9 20.9 43.4 24.8 94.1 40.4 61.0 9.5 90.6 17.7 41.0 32.1 4.4 45.4 85.9 20.3 24.3 55.8 15.0 22.9 30.4 49.6 38.0 14.3 10.3 32.4 44.4 70.3 17.0 22.6 143.6 23.9 16.6 23.3 20.2 12.5 25.2 23.2 80.8 18.3 80.3 34.8 7.4 10.4 8.7 7.5 8.7 15.3 8.8 9.0 4.7 18.3 11.4 11.8 19.8 16.3 6.8 16.5 9.3 4.3 25.4 21.3 26.2 36.2 35.5 29.5 30.5 22.9 33.0 9.4 25.2 37.3 48.2 44.8 78.5 94.0 36.6 8.8 32.2 44.6 15.9 108.1 29.3 20.7 23.7 28.6 74.3 90.1 160.6 23.1 36.2 64.0 15.6 36.5 13.6 111.3 29.8 31.7 56.3 112.9 153.8 28.7 42.0 24.2 41.8 124.4 32.2 44.8 30.7 16.1 21.9 85.8 113.5 49.2 42.7 48.8 12.8 21.9 27.7 31.8 10.6 49.6 25.0 24.4 40.2 89.0 138.7 47.1 42.3 26.7 29.7 23.9 56.8 12.0 82.3 50.0 32.9 33.4 27.5 6.3 29.9 19.2 8.4 66.5 34.2 39.3 32.1 24.2 ZNF101 "DKFZp570I0164, HZF12" ENSG00000181896 "Zinc finger protein 101" Q8IZC7 19 19668796-19683509 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 27.6" "Cell type enhanced" "Detected in many" "NK-cells: 24.7;T-cells: 23.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 82.5" "HPA023449, HPA055486" Uncertain NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA023449: AB_2671211, HPA055486: AB_2682831" "unprognostic (5.05e-2)" "prognostic favorable (5.76e-5)" "unprognostic (1.68e-2)" "unprognostic (2.81e-1)" "unprognostic (1.11e-1)" "prognostic favorable (2.15e-4)" "unprognostic (2.43e-1)" "prognostic favorable (6.65e-4)" "unprognostic (1.62e-2)" "prognostic favorable (2.26e-4)" "unprognostic (9.34e-3)" "unprognostic (1.63e-2)" "unprognostic (8.84e-3)" "prognostic favorable (1.11e-4)" "unprognostic (3.15e-2)" "unprognostic (7.02e-2)" "prognostic favorable (4.37e-4)" 3.2 2.0 2.1 13.1 2.2 13.2 6.2 3.0 3.6 3.2 2.1 4.8 3.2 2.3 2.8 6.9 2.4 2.6 2.2 2.3 1.7 4.1 3.1 3.4 27.6 2.4 2.0 1.8 2.4 2.0 1.9 3.3 2.4 2.3 4.5 4.2 3.1 1.9 1.7 3.7 8.2 2.1 1.7 11.1 4.6 10.6 2.5 25.4 3.1 1.3 24.7 5.6 3.0 3.2 6.0 5.5 6.7 8.7 2.5 4.5 13.3 7.0 3.8 5.3 9.2 6.9 7.8 35.5 7.5 3.7 5.6 5.6 11.8 7.1 10.7 4.7 6.2 11.2 5.1 11.0 2.0 20.9 18.7 3.5 4.0 9.7 7.1 3.2 6.7 25.7 8.1 19.8 6.5 7.2 27.4 6.8 18.8 6.2 8.6 10.3 8.9 16.0 5.5 10.1 3.4 4.1 8.0 5.1 2.5 8.3 7.7 12.0 5.3 7.5 2.9 11.6 7.2 9.5 18.8 82.5 4.4 11.2 7.2 16.4 4.3 7.7 12.8 5.9 23.2 13.8 30.9 20.3 6.4 15.6 43.3 32.3 6.0 11.1 7.4 10.1 61.2 16.0 2.1 2.2 3.0 3.6 2.3 1.7 2.4 2.0 2.4 1.7 2.5 3.2 6.0 12.8 6.8 2.0 18.2 2.5 2.2 4.1 1.2 7.3 5.0 3.8 2.8 1.5 4.3 9.2 6.2 5.6 9.8 5.1 3.9 4.5 12.7 2.9 2.7 6.5 3.0 4.2 3.1 6.6 5.1 2.5 2.6 3.6 6.3 4.0 5.7 3.1 6.8 1.7 3.0 3.7 0.0 9.7 3.5 9.9 2.8 5.7 3.6 1.0 8.8 3.5 24.7 4.0 3.6 5.5 4.6 1.5 13.9 2.9 4.3 2.9 5.8 11.5 0.0 3.3 2.7 13.0 8.6 1.8 2.3 2.1 23.8 2.5 2.7 3.3 ZNF184 ENSG00000096654 "Zinc finger protein 184" Q99676 6 27450743-27473118 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 36.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003226, HPA064793" Uncertain Supported Nucleoplasm NA NA "Cluster 13: T-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 14: REH - Unknown function" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA003226: AB_2218705, HPA064793: AB_2732722" "unprognostic (8.86e-2)" "unprognostic (5.55e-2)" "unprognostic (2.27e-3)" "unprognostic (1.70e-1)" "unprognostic (4.99e-3)" "unprognostic (6.04e-2)" "unprognostic (1.99e-2)" "unprognostic (1.74e-2)" "unprognostic (1.17e-2)" "prognostic favorable (4.41e-5)" "unprognostic (2.59e-1)" "unprognostic (5.64e-2)" "unprognostic (2.77e-2)" "unprognostic (1.30e-1)" "unprognostic (1.05e-1)" "unprognostic (2.31e-2)" "unprognostic (5.79e-3)" 2.8 3.1 2.4 4.3 4.6 8.8 5.4 1.2 8.4 6.1 0.0 4.4 3.4 5.4 4.1 3.8 4.5 4.0 2.8 6.4 0.6 7.0 3.6 4.1 6.3 0.4 0.3 6.0 2.7 5.9 4.1 3.0 0.3 4.3 4.5 4.4 3.5 4.3 2.9 5.7 3.6 4.3 0.6 4.6 4.4 8.3 0.3 10.2 5.6 5.0 6.6 4.5 2.9 2.7 6.4 2.0 10.8 19.7 7.6 5.6 3.6 6.2 8.3 7.1 10.9 3.6 3.7 11.7 10.3 4.0 4.8 3.9 9.7 4.0 10.3 11.4 6.0 14.0 7.3 5.1 4.0 16.9 9.7 4.1 6.0 5.2 5.4 8.4 7.8 17.8 10.9 21.1 11.9 3.2 27.3 14.3 6.3 3.5 4.5 35.4 15.2 17.5 4.9 5.9 18.4 8.9 7.0 6.0 9.2 5.3 7.0 14.4 5.3 10.8 7.1 4.9 7.2 9.6 17.4 21.8 2.4 19.4 10.9 2.1 2.7 8.0 7.9 3.7 10.9 7.4 8.3 7.7 4.1 6.9 6.3 7.9 1.4 7.0 2.9 2.5 10.4 3.9 2.4 4.6 1.2 8.4 6.4 0.6 0.4 0.3 0.3 0.6 0.3 2.7 5.4 6.4 8.1 2.0 9.8 4.1 3.8 2.5 6.8 2.5 5.1 5.5 3.5 2.8 6.4 1.8 2.1 4.3 17.5 2.1 7.9 2.7 36.9 7.9 3.7 5.1 7.1 3.4 10.3 3.0 3.0 4.5 2.0 5.0 5.1 7.4 3.9 1.5 2.8 10.1 3.4 5.1 2.0 3.8 3.8 12.6 3.4 3.6 1.8 5.6 3.0 3.3 9.2 4.0 4.2 2.5 2.1 3.8 6.5 4.6 1.6 4.5 6.3 4.8 0.0 5.2 6.8 12.8 5.9 4.3 4.4 2.9 12.5 4.6 4.4 4.5 ZNF214 ENSG00000149050 "Zinc finger protein 214" Q9UL59 11 6997085-7020346 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 6.6;Endometrial ciliated cells: 6.6;Excitatory neurons: 10.5;Respiratory ciliated cells: 10.4;Spermatocytes: 10.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 3.5" HPA055391 Uncertain Approved Nucleoplasm,Midbody Yes NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 12: NES - Nervous system development" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm Midbody "HPA055391: AB_2682804" "unprognostic (3.01e-2)" "unprognostic (3.04e-1)" "unprognostic (1.56e-2)" "unprognostic (2.33e-1)" "unprognostic (8.77e-2)" "unprognostic (2.43e-2)" "unprognostic (3.28e-3)" "unprognostic (7.53e-4)" "unprognostic (1.71e-1)" "unprognostic (1.39e-2)" "unprognostic (3.21e-1)" "unprognostic (1.29e-1)" "unprognostic (3.67e-3)" "unprognostic (3.00e-2)" "unprognostic (3.21e-2)" "unprognostic (1.16e-1)" "unprognostic (6.22e-2)" 0.6 1.0 1.0 0.2 1.2 0.0 2.1 0.8 1.5 2.3 1.8 1.2 0.5 2.3 2.7 0.5 3.9 0.8 0.8 0.9 1.1 2.4 1.2 1.2 0.2 1.8 1.7 4.2 1.0 2.5 1.3 0.1 1.1 2.0 1.1 5.3 0.9 2.1 0.4 0.4 0.6 1.7 1.2 0.2 0.7 3.1 1.0 0.2 3.4 0.5 0.2 1.4 1.3 1.4 0.4 0.8 3.3 0.0 0.6 2.2 0.8 1.3 3.5 1.7 1.9 0.0 2.4 0.1 0.4 0.9 1.1 0.5 0.3 0.9 1.9 0.0 0.9 0.0 0.5 0.2 1.2 0.0 0.1 0.6 2.2 0.0 1.9 2.3 1.5 0.0 0.2 0.0 0.6 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 2.2 0.5 0.0 2.6 1.3 0.1 0.1 1.3 0.5 0.0 0.2 1.1 1.4 3.0 0.0 0.0 0.0 0.0 1.9 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.2 0.8 1.5 0.9 1.1 1.8 1.7 1.1 1.2 1.0 1.4 0.5 0.0 1.5 4.6 0.1 0.0 2.0 1.6 0.6 2.5 1.1 1.5 0.9 1.5 2.7 0.0 0.0 0.1 0.0 0.4 1.9 2.1 6.6 6.6 2.0 0.6 2.4 0.0 10.5 0.9 0.4 1.5 0.0 0.9 0.0 1.2 0.0 0.4 0.1 3.3 5.5 1.7 0.0 0.0 0.5 1.0 0.6 0.2 0.0 2.8 0.0 3.0 0.0 4.0 2.9 1.1 0.1 0.4 0.0 0.6 0.8 3.3 10.4 3.6 0.0 0.8 0.9 10.4 3.3 0.9 0.1 0.0 0.2 0.8 0.9 0.4 ZNF219 ENSG00000165804 "Zinc finger protein 219" Q9P2Y4 14 21090077-21104722 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030761, HPA056168" Approved Supported Nucleoplasm NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 72: Non-specific - Transcription" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA030761: AB_2673598, HPA056168: AB_2683052" "unprognostic (9.82e-3)" "unprognostic (4.50e-3)" "unprognostic (3.35e-1)" "unprognostic (1.11e-3)" "unprognostic (4.49e-2)" "unprognostic (1.96e-1)" "unprognostic (2.54e-1)" "unprognostic (6.79e-2)" "unprognostic (2.62e-2)" "unprognostic (1.70e-1)" "unprognostic (6.02e-2)" "unprognostic (1.30e-1)" "unprognostic (1.80e-3)" "unprognostic (6.28e-2)" "unprognostic (1.92e-1)" "unprognostic (2.56e-2)" "unprognostic (2.35e-2)" 44.2 77.1 15.2 7.4 10.7 4.5 35.5 32.0 17.9 33.9 14.3 83.3 22.4 41.6 9.4 49.2 29.6 5.4 42.0 22.0 14.8 20.6 17.1 32.8 2.5 20.7 25.7 30.7 24.7 12.4 23.5 6.5 20.3 38.3 10.3 11.0 28.2 21.7 34.0 45.6 33.1 9.3 13.6 13.1 33.3 11.9 17.8 10.9 32.3 5.9 3.6 44.7 36.1 9.1 8.1 26.6 33.6 49.5 4.5 4.3 48.1 9.8 15.0 4.9 7.7 15.5 17.7 12.0 7.2 3.7 5.4 59.1 10.8 31.4 3.4 24.6 11.5 7.1 42.2 32.7 2.8 1.5 10.9 6.6 25.9 8.0 14.7 6.5 6.0 11.0 6.9 3.5 2.7 22.4 16.2 11.3 47.5 15.3 5.7 33.7 5.6 3.1 3.8 44.0 38.2 34.4 13.5 7.9 7.8 6.7 9.5 4.2 1.2 6.0 26.4 14.7 4.0 6.1 4.2 2.7 3.8 6.0 11.8 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.6 0.1 0.0 0.4 0.0 0.0 15.2 10.7 32.0 17.9 22.0 14.8 20.7 25.7 20.3 13.6 17.8 9.1 5.6 3.2 10.7 12.7 1.8 14.8 13.3 13.5 11.4 36.6 14.4 19.6 7.6 10.0 4.3 3.7 27.1 9.6 3.4 33.0 1.9 10.3 9.2 2.5 1.9 6.3 7.8 8.2 3.5 11.3 1.0 6.0 5.1 4.6 14.7 35.1 9.3 8.0 7.4 11.8 4.9 17.4 10.2 7.5 11.8 5.6 9.9 5.9 8.8 7.5 0.8 33.0 1.0 13.6 2.5 7.8 10.0 12.4 3.9 12.0 23.6 6.8 4.3 27.4 13.1 9.3 14.7 8.9 8.7 13.5 15.6 12.4 5.2 6.3 26.6 12.7 ZNF225 ENSG00000256294 "Zinc finger protein 225" Q9UK10 19 44112181-44134822 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 9.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SK-BR-3: 18.1" HPA073778 Approved Nucleoplasm NA NA "Cluster 34: Basophils - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm "HPA073778: AB_2686634" "unprognostic (1.52e-1)" "unprognostic (8.99e-2)" "unprognostic (1.36e-1)" "unprognostic (1.65e-1)" "unprognostic (1.45e-2)" "unprognostic (1.59e-2)" "unprognostic (9.03e-2)" "unprognostic (7.54e-2)" "unprognostic (1.26e-2)" "unprognostic (6.82e-2)" "unprognostic (7.18e-3)" "unprognostic (5.67e-2)" "unprognostic (7.54e-2)" "unprognostic (1.84e-1)" "unprognostic (6.60e-2)" "unprognostic (5.90e-2)" "unprognostic (3.17e-4)" 2.2 3.2 4.3 2.7 5.6 2.3 8.0 5.5 5.3 4.1 4.4 2.5 2.4 3.4 2.5 2.1 3.2 2.8 3.2 4.1 4.9 3.0 2.7 2.7 3.7 4.8 5.0 5.2 1.9 4.5 2.5 3.3 4.7 3.3 2.4 7.0 3.0 3.5 2.5 3.1 2.2 2.5 4.4 4.0 3.0 12.8 4.9 5.3 4.1 2.4 3.9 2.6 2.0 7.0 2.6 4.2 5.4 6.3 7.9 7.0 1.2 4.2 6.4 4.9 6.3 2.6 1.6 1.1 3.2 4.6 2.8 2.2 5.0 3.1 4.3 2.6 4.8 7.7 5.4 2.4 4.6 4.7 6.8 6.6 3.7 4.4 7.1 8.3 4.8 3.4 2.3 1.3 4.2 0.8 3.4 3.3 4.8 1.9 4.3 2.8 7.4 2.5 4.8 5.2 3.2 5.6 7.6 18.1 2.3 5.5 2.0 8.0 4.9 4.5 4.7 2.2 2.8 5.9 3.8 0.8 2.1 2.8 4.1 11.6 3.2 5.2 3.4 4.6 3.3 3.3 2.5 2.6 4.4 5.3 4.7 3.5 0.7 4.4 1.9 2.0 3.8 2.4 4.3 5.6 5.5 5.3 4.1 4.9 4.8 5.0 4.7 4.4 4.9 7.0 1.5 0.0 1.7 3.9 2.7 0.3 0.7 0.5 1.2 4.3 1.3 1.0 1.6 1.5 1.5 1.8 0.0 2.3 6.0 1.0 3.9 1.3 9.7 0.7 1.9 2.0 1.2 4.4 3.4 1.3 1.1 2.1 2.6 0.7 0.0 3.8 2.9 1.8 1.5 6.7 3.4 1.0 0.0 3.5 1.1 2.0 2.8 1.3 0.0 0.0 1.3 3.0 3.1 2.5 5.8 1.3 1.9 1.9 1.4 0.4 1.5 1.2 1.7 4.3 0.0 2.3 1.6 4.1 2.2 0.5 0.4 0.3 2.1 3.4 0.9 0.5 ZNF233 FLJ38032 ENSG00000159915 "Zinc finger protein 233" A6NK53 19 44259880-44275317 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 14.2" "Group enriched" "Detected in some" 4 "Early spermatids: 40.9;Spermatocytes: 38.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-266/70: 6.9;U-266/84: 7.6" HPA020975 Uncertain Approved Nucleoplasm NA NA "Cluster 6: Non-specific - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 16: U-266 - Nucleosome" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "HPA020975: AB_1859145" "unprognostic (2.26e-1)" "unprognostic (1.53e-1)" "unprognostic (1.05e-1)" "unprognostic (4.78e-1)" "unprognostic (1.60e-1)" "unprognostic (3.72e-2)" "unprognostic (7.37e-3)" "unprognostic (2.77e-2)" "unprognostic (9.07e-3)" "unprognostic (1.48e-1)" "unprognostic (4.20e-3)" "unprognostic (1.65e-1)" "unprognostic (6.28e-3)" "unprognostic (6.88e-2)" "unprognostic (3.47e-2)" "unprognostic (2.71e-4)" "unprognostic (1.55e-1)" 0.4 1.1 1.8 1.1 1.9 1.8 1.5 3.4 3.1 0.7 0.4 3.0 0.9 0.4 1.6 0.6 1.3 0.9 3.2 1.5 1.8 1.3 0.5 0.6 1.3 1.2 0.1 0.5 0.8 1.7 3.1 1.3 1.5 2.7 1.3 4.9 0.9 1.0 1.7 1.6 1.0 0.4 0.3 1.3 1.1 14.2 0.9 1.5 1.9 0.6 0.6 0.8 0.4 2.5 0.4 1.8 2.0 1.9 2.2 0.4 0.5 0.7 0.6 0.7 1.2 1.5 2.1 0.6 1.9 0.6 1.1 0.6 0.0 0.5 0.8 0.3 2.4 1.0 2.5 1.7 1.5 0.7 0.8 0.5 0.3 0.5 1.3 2.9 0.9 0.7 0.8 3.8 0.1 0.7 0.6 0.5 2.1 0.4 0.3 1.2 0.2 0.8 0.4 1.2 2.8 4.4 0.7 0.5 1.3 3.7 3.5 1.0 0.3 0.6 0.4 0.4 0.4 6.9 7.6 1.2 3.0 0.5 0.9 1.5 0.3 0.2 0.5 0.3 0.4 0.9 0.4 0.3 0.1 1.3 0.6 0.7 0.7 1.1 0.3 1.3 0.7 0.1 1.8 1.9 3.4 3.1 1.5 1.8 1.2 0.1 1.5 0.3 0.9 2.5 0.5 0.0 0.5 2.6 0.4 0.0 0.2 0.2 0.0 3.7 1.1 0.4 4.6 0.0 0.3 0.0 0.0 0.5 0.2 0.3 0.0 0.6 40.9 1.3 0.3 0.9 1.2 0.4 9.0 0.0 0.1 0.6 0.5 0.5 0.0 0.7 0.0 0.0 0.6 0.0 7.9 0.2 2.0 0.0 0.0 8.5 0.6 0.1 0.0 1.0 0.0 1.9 0.0 4.5 5.7 0.1 0.1 0.7 0.0 0.5 0.8 0.0 0.4 4.0 0.0 0.6 0.4 38.6 1.9 0.0 0.0 0.0 0.3 1.1 0.4 0.1 ZNF275 ENSG00000063587 "Zinc finger protein 275" Q9NSD4 X 153334147-153360110 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 77.5" "Cell type enhanced" "Detected in many" "Granulosa cells: 76.3;Peritubular cells: 39.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-266/70: 57.3" HPA000566 Approved Approved Nucleoli NA NA "Cluster 35: T-regs - Unknown function" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 29: U-266 - Adaptive immune response" "Cluster 40: Granulosa cells - Unknown function" Nucleoli "HPA000566: AB_1080700" "unprognostic (6.96e-2)" "unprognostic (8.97e-2)" "unprognostic (3.10e-2)" "unprognostic (1.11e-3)" "unprognostic (5.25e-2)" "unprognostic (1.45e-1)" "unprognostic (9.59e-2)" "unprognostic (9.37e-2)" "unprognostic (2.80e-1)" "unprognostic (1.29e-1)" "unprognostic (1.03e-1)" "unprognostic (2.64e-1)" "unprognostic (4.33e-2)" "unprognostic (2.69e-1)" "unprognostic (1.95e-1)" "unprognostic (3.74e-2)" "unprognostic (1.14e-2)" 8.5 77.5 10.1 5.1 10.5 3.1 7.6 10.6 9.7 7.9 10.1 5.2 3.9 8.4 17.6 2.8 8.5 7.2 4.4 9.5 11.9 5.5 13.5 4.1 6.3 11.3 10.8 42.6 10.1 32.3 11.0 3.1 11.1 7.2 4.3 5.2 6.5 14.5 4.8 2.4 6.1 7.3 11.7 11.1 6.0 8.5 12.9 6.3 6.9 7.3 8.0 4.7 3.0 12.7 10.2 4.1 8.4 6.1 10.0 9.6 4.1 7.0 11.7 4.4 6.6 4.3 2.1 17.0 14.0 13.3 6.7 1.7 10.1 6.2 6.5 4.1 7.8 5.7 3.8 6.6 13.4 7.0 4.8 11.4 4.5 3.7 7.2 7.2 5.5 9.2 8.5 0.0 8.1 7.4 8.2 5.8 3.7 10.3 7.2 9.6 9.3 6.0 3.3 6.1 4.3 5.8 3.5 0.3 8.4 5.2 1.5 13.0 5.8 6.5 7.8 10.9 9.1 57.3 16.9 32.9 5.9 13.5 4.6 0.3 0.8 0.1 1.6 0.7 1.9 1.9 1.5 1.5 0.7 2.0 2.1 1.8 0.0 1.4 0.7 1.3 2.4 1.0 10.1 10.5 10.6 9.7 9.5 11.9 11.3 10.8 11.1 11.7 12.9 12.7 26.1 0.0 4.6 7.8 10.9 3.3 4.0 3.6 3.4 6.5 6.2 3.9 5.2 10.0 2.3 9.2 12.5 1.4 9.8 2.6 7.9 2.8 1.3 4.5 15.3 6.6 0.0 8.2 3.8 5.0 4.4 10.5 8.6 8.8 2.5 76.3 7.5 28.3 2.5 0.0 4.8 5.8 4.1 6.0 3.5 4.4 14.3 3.5 3.6 2.8 4.5 6.5 6.2 7.5 3.7 3.9 3.2 39.5 28.7 6.1 2.1 8.3 1.6 2.8 13.1 12.8 11.8 3.5 3.7 4.3 2.3 0.8 7.0 21.5 5.3 2.1 ZNF35 "HF.10, HF10, Zfp105" ENSG00000169981 "Zinc finger protein 35" P13682 3 44648732-44660791 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 30.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051859, HPA054738" Uncertain Approved Nucleoplasm NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 71: Testis - DNA repair" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "HPA051859: AB_2681642, HPA054738: AB_2682588" "unprognostic (1.54e-1)" "unprognostic (1.81e-1)" "unprognostic (1.77e-2)" "unprognostic (1.41e-1)" "unprognostic (8.91e-3)" "unprognostic (9.91e-2)" "unprognostic (6.68e-2)" "unprognostic (1.48e-1)" "unprognostic (2.01e-2)" "unprognostic (4.54e-2)" "unprognostic (1.47e-2)" "unprognostic (1.69e-2)" "unprognostic (9.08e-3)" "unprognostic (1.23e-1)" "unprognostic (8.64e-2)" "unprognostic (1.60e-3)" "unprognostic (3.30e-1)" 3.9 2.7 2.2 1.6 2.4 1.9 3.1 2.9 2.5 3.1 1.4 4.1 1.3 4.3 2.8 3.9 2.8 1.7 4.0 2.3 2.4 3.5 2.0 2.8 1.4 2.3 2.5 2.3 2.8 2.0 3.5 1.4 2.4 3.4 1.6 2.5 3.1 2.1 3.8 3.3 2.9 3.2 2.1 3.1 3.2 7.1 2.3 1.3 3.1 2.3 2.4 3.6 3.3 2.9 3.2 2.4 6.2 8.0 4.0 3.2 1.1 3.9 5.4 6.7 6.4 4.3 1.4 2.8 1.7 5.4 2.9 2.2 0.3 5.6 6.9 0.1 2.2 9.3 4.3 0.2 3.6 9.3 6.8 3.3 4.1 6.0 5.3 3.3 5.4 0.0 6.3 2.6 7.4 1.9 0.2 3.0 13.9 2.3 6.7 0.1 6.6 4.9 3.6 9.0 3.4 8.8 4.9 3.0 0.8 5.1 8.0 5.7 5.7 7.1 5.2 3.9 7.8 7.1 11.8 1.6 6.1 4.5 5.6 0.0 1.7 0.7 0.9 1.9 0.6 1.5 0.2 1.0 1.8 1.9 0.4 0.5 0.1 2.3 1.8 0.7 0.1 1.0 2.2 2.4 2.9 2.5 2.3 2.4 2.3 2.5 2.4 2.1 2.3 2.9 6.6 6.4 8.7 6.8 5.3 2.8 3.9 3.0 1.8 4.9 4.8 3.4 3.2 2.8 3.3 1.8 0.0 0.3 3.7 2.8 1.9 8.1 10.2 2.2 4.2 9.3 2.4 3.8 7.5 8.7 0.1 5.8 2.6 3.5 0.0 5.7 5.0 1.5 3.8 6.7 8.5 2.4 10.2 2.8 1.4 6.5 1.2 3.2 1.8 4.7 3.6 4.4 7.2 8.0 11.2 10.3 3.3 4.5 4.0 4.3 2.0 3.8 3.4 6.4 0.0 4.8 5.5 30.7 11.7 3.0 2.8 0.4 2.6 5.7 3.0 3.3 ZNF366 FLJ39796 ENSG00000178175 "Zinc finger protein 366" Q8N895 5 72439903-72507410 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 19.0;Cone photoreceptor cells: 31.3;Endothelial cells: 18.3;Langerhans cells: 9.3;Microglial cells: 54.4;monocytes: 14.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "myeloid DC: 10.4" "Lineage enriched" "Detected in many" 9 "dendritic cells: 10.4" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 1.3;TIME: 1.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA023128, HPA023526, HPA074074" Uncertain Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "Plasma membrane" "HPA023128: AB_1859223, HPA023526: AB_1859224, HPA074074: " "unprognostic (3.49e-1)" "unprognostic (8.44e-2)" "unprognostic (2.44e-1)" "unprognostic (2.27e-1)" "unprognostic (6.17e-2)" "unprognostic (1.95e-3)" "unprognostic (9.25e-2)" "unprognostic (6.67e-2)" "unprognostic (1.43e-1)" "unprognostic (2.47e-1)" "unprognostic (1.34e-1)" "unprognostic (1.27e-1)" "unprognostic (1.88e-3)" "unprognostic (1.53e-1)" "unprognostic (1.61e-1)" "unprognostic (1.43e-1)" "unprognostic (6.29e-2)" 5.8 0.8 6.1 3.4 5.0 0.1 3.2 4.5 5.6 2.8 2.4 1.4 1.5 3.1 0.7 1.8 2.4 2.3 3.8 4.1 4.6 2.1 1.0 2.6 5.0 5.8 5.5 0.8 0.7 1.1 0.4 8.9 6.0 0.9 1.5 0.5 0.8 1.5 5.0 2.2 1.9 3.9 4.1 6.4 1.4 0.5 7.1 3.1 2.2 5.6 4.0 1.7 1.0 4.5 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.5 6.1 5.0 4.5 5.6 4.1 4.6 5.8 5.5 6.0 4.1 7.1 4.5 19.0 0.0 0.6 0.0 0.1 0.5 0.4 0.0 0.6 0.4 0.1 0.3 1.6 0.0 0.6 0.0 31.3 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 18.3 0.0 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 6.8 0.4 0.5 0.0 0.3 0.0 0.0 4.6 9.3 0.5 0.3 2.4 0.0 54.4 14.5 0.1 0.0 0.5 0.3 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.8 0.0 1.2 0.7 0.0 0.0 0.2 0.3 0.1 0.3 0.1 0.0 0.0 ZNF438 bA330O11.1 ENSG00000183621 "Zinc finger protein 438" Q7Z4V0 10 30820207-31031937 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 111.3;Excitatory neurons: 55.3;Inhibitory neurons: 74.7;Microglial cells: 76.8;Oligodendrocyte precursor cells: 137.2;Oligodendrocytes: 86.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 19.0;U-937: 25.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039843 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 32: U-937 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" Nucleoplasm Cytosol "HPA039843: AB_10795159" "unprognostic (1.69e-1)" "unprognostic (9.49e-3)" "unprognostic (3.72e-2)" "unprognostic (9.21e-2)" "unprognostic (4.75e-2)" "unprognostic (1.22e-2)" "unprognostic (3.98e-3)" "unprognostic (1.30e-1)" "unprognostic (4.65e-1)" "unprognostic (2.33e-1)" "unprognostic (2.11e-2)" "unprognostic (4.85e-2)" "unprognostic (1.08e-2)" "unprognostic (9.96e-2)" "unprognostic (1.52e-1)" "unprognostic (8.52e-3)" "unprognostic (9.50e-2)" 11.9 3.6 5.5 6.4 5.7 5.5 7.4 5.1 7.3 8.5 5.7 11.3 3.8 9.2 6.6 4.6 8.2 5.6 11.0 5.6 5.8 4.4 5.4 8.4 4.0 5.3 5.2 5.9 3.1 3.7 4.9 4.0 5.5 5.4 4.1 4.5 6.2 5.6 24.6 6.8 5.3 8.7 5.3 10.3 6.0 8.4 6.3 7.8 9.7 17.4 3.1 9.3 6.8 6.5 3.7 3.7 3.1 2.7 18.0 12.5 1.7 2.9 4.2 4.5 5.6 0.2 4.4 5.0 3.3 5.2 4.2 1.0 1.6 2.2 6.3 11.6 1.2 2.2 2.0 0.2 10.1 1.7 2.3 6.0 3.7 6.4 3.6 4.1 19.0 5.8 4.3 3.5 6.2 2.7 5.9 9.7 0.3 2.7 1.5 2.6 4.5 2.9 6.4 0.9 2.3 2.5 1.4 0.6 2.1 2.0 1.4 16.2 7.9 2.0 3.5 6.1 3.6 0.8 1.5 0.1 4.0 25.3 1.5 1.3 7.2 3.3 2.0 6.9 1.5 1.0 1.5 2.7 2.2 3.7 3.1 1.7 13.1 3.9 4.3 2.8 3.6 3.5 5.5 5.7 5.1 7.3 5.6 5.8 5.3 5.2 5.5 5.3 6.3 6.5 7.8 3.2 4.8 111.3 3.2 1.0 2.0 1.7 5.2 5.5 2.1 2.2 13.0 5.7 4.2 3.7 6.2 3.5 2.0 1.8 7.9 3.6 25.2 2.7 5.6 6.1 0.0 2.5 55.3 4.2 4.6 9.1 7.1 2.4 12.6 4.1 6.4 1.8 6.9 3.3 74.7 2.6 0.0 12.9 3.5 9.6 4.1 36.3 0.0 76.8 7.3 2.4 7.2 137.2 86.9 3.7 0.8 8.2 3.6 1.3 2.5 3.9 3.9 5.3 6.6 17.0 6.7 12.8 8.0 6.0 2.4 1.6 4.2 2.4 2.3 1.8 ZNF461 "GIOT-1, MGC33911" ENSG00000197808 "Zinc finger protein 461" Q8TAF7 19 36636618-36666853 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 28.9;Alveolar cells type 2: 23.8;Early spermatids: 43.5;granulocytes: 33.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA021139 Uncertain Approved "Nucleoplasm,Nucleoli,Golgi apparatus" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 60: Granulocytes - Receptor signaling" "Golgi apparatus" "Nucleoplasm, Nucleoli" "HPA021139: AB_10961418" "unprognostic (8.37e-3)" "unprognostic (2.23e-1)" "unprognostic (1.74e-1)" "prognostic unfavorable (3.64e-4)" "unprognostic (2.08e-2)" "unprognostic (6.32e-2)" "unprognostic (5.60e-2)" "unprognostic (1.57e-1)" "unprognostic (1.79e-3)" "unprognostic (2.11e-1)" "unprognostic (7.01e-3)" "unprognostic (2.43e-2)" "unprognostic (1.51e-1)" "unprognostic (4.21e-2)" "unprognostic (4.54e-2)" "unprognostic (5.86e-2)" "unprognostic (5.11e-3)" 2.2 3.6 3.5 2.0 3.4 3.0 3.0 6.2 5.2 2.0 1.7 2.2 0.5 3.3 2.5 2.1 3.0 2.0 2.3 3.5 3.4 2.7 2.0 2.0 3.2 2.3 2.6 4.4 1.3 3.2 3.0 3.4 2.6 2.8 1.9 6.6 1.6 2.2 2.2 3.0 1.9 3.2 2.4 3.5 2.5 3.7 3.5 2.5 4.1 2.1 3.2 2.0 2.0 3.7 2.9 4.7 3.5 4.8 2.6 4.9 2.4 2.9 3.0 4.2 5.8 0.8 1.4 0.4 6.2 3.8 4.2 0.6 2.5 3.0 4.6 5.6 3.4 4.9 0.7 1.9 4.1 3.7 5.5 3.5 5.6 1.5 4.3 5.6 2.6 2.4 0.2 0.5 4.3 2.7 6.1 1.7 2.3 0.4 2.1 0.4 3.6 1.0 1.8 6.3 4.6 6.1 0.3 2.1 3.8 3.5 2.2 1.5 3.2 2.5 3.4 2.1 3.7 7.6 12.2 1.6 0.0 0.8 3.6 0.8 0.5 0.5 1.3 1.1 1.7 1.5 2.1 2.8 1.2 2.0 1.6 1.3 0.1 1.4 0.2 0.5 2.0 0.9 3.5 3.4 6.2 5.2 3.5 3.4 2.3 2.6 2.6 2.4 3.5 3.7 2.3 28.9 23.8 8.1 4.1 3.3 2.0 2.3 4.6 5.4 4.7 2.5 2.2 7.2 12.9 3.7 0.0 2.5 2.6 0.9 1.9 1.7 43.5 4.6 2.9 5.2 3.0 0.8 16.3 0.9 2.9 6.2 1.5 4.6 33.5 3.1 2.9 1.2 1.7 3.3 14.0 1.1 0.0 2.5 3.2 8.3 0.9 3.2 0.0 4.7 0.9 1.6 1.0 9.0 12.4 0.8 0.5 1.9 1.2 2.3 0.8 1.8 9.9 3.6 0.0 4.9 3.9 10.2 4.0 3.1 3.4 2.9 6.1 1.9 1.3 1.8 ZNF473 "DKFZP434N043, HZFP100, KIAA1141" ENSG00000142528 "Zinc finger protein 473" Q8WTR7 19 50025714-50053414 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "testis: 42.4" "Cell type enhanced" "Detected in many" "Early spermatids: 88.9;Late spermatids: 23.3;Spermatocytes: 64.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA004191, HPA073309" Approved Supported Nucleoplasm NA NA "Cluster 30: Non-specific - Translation" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 1: K-562 - Erythropoiesis" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "HPA004191: AB_2667168, HPA073309: AB_2686594" "unprognostic (7.47e-3)" "unprognostic (3.57e-2)" "unprognostic (2.47e-1)" "unprognostic (3.40e-1)" "unprognostic (4.27e-1)" "unprognostic (8.00e-3)" "prognostic unfavorable (3.72e-4)" "unprognostic (1.31e-3)" "unprognostic (6.44e-3)" "unprognostic (1.42e-1)" "unprognostic (1.70e-2)" "unprognostic (3.22e-3)" "unprognostic (8.49e-2)" "unprognostic (1.60e-1)" "unprognostic (3.93e-2)" "unprognostic (7.76e-2)" "unprognostic (1.08e-1)" 3.8 2.9 4.0 2.9 4.9 4.2 4.6 5.7 7.6 3.6 9.0 3.1 2.8 3.7 4.0 3.6 7.3 3.2 2.9 4.4 5.0 3.5 3.3 3.5 3.5 5.2 5.8 4.4 4.6 4.3 5.4 3.0 4.8 4.7 3.0 6.2 2.4 3.9 4.1 3.7 2.4 4.9 4.7 6.7 3.1 42.4 5.4 4.1 4.5 4.6 4.5 3.2 2.4 6.8 14.4 9.6 14.7 12.4 5.7 6.6 8.3 13.2 7.9 18.4 17.2 18.4 9.5 22.2 5.0 7.7 6.8 10.8 18.4 8.8 23.4 15.6 18.0 22.5 8.8 9.3 6.6 16.3 13.1 6.8 16.1 19.3 25.2 7.6 6.2 13.1 32.1 19.3 9.4 6.2 13.0 7.8 10.4 22.4 15.1 15.8 20.5 9.8 6.1 15.6 12.1 13.9 18.6 10.1 8.9 10.0 9.4 14.7 3.0 25.7 13.1 5.2 13.4 8.9 22.8 18.4 6.1 12.7 21.0 2.0 5.0 2.9 6.3 7.3 6.6 11.7 6.3 7.7 5.0 10.0 7.8 10.0 4.4 2.5 3.4 5.3 3.9 4.2 4.0 4.9 5.7 7.6 4.4 5.0 5.2 5.8 4.8 4.7 5.4 6.8 2.8 0.0 1.7 0.3 4.6 4.6 2.9 1.9 6.8 0.7 2.9 2.8 2.2 0.0 1.7 0.0 0.0 2.3 1.5 2.3 3.9 2.4 88.9 5.6 5.1 3.8 1.8 5.2 3.1 3.2 3.2 3.5 7.7 4.0 0.0 3.8 6.8 1.7 2.2 0.0 3.1 3.7 2.0 1.3 1.7 23.3 3.7 2.0 1.8 1.9 3.2 1.7 2.1 1.5 2.8 3.4 3.0 3.8 4.1 4.1 1.6 1.7 10.4 4.3 13.1 3.5 2.7 64.7 20.5 4.8 4.7 1.9 3.5 3.5 2.4 2.1 ZNF497 FLJ44773 ENSG00000174586 "Zinc finger protein 497" Q6ZNH5 19 58354357-58362848 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 6.4;Respiratory ciliated cells: 5.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEK 293: 20.2" HPA047872 Uncertain Approved "Nucleoplasm,Cell Junctions" NA NA "Cluster 30: Non-specific - Translation" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "Cell Junctions" "HPA047872: AB_2680196" "unprognostic (8.24e-2)" "unprognostic (1.12e-1)" "unprognostic (2.17e-1)" "unprognostic (1.09e-3)" "unprognostic (1.02e-1)" "unprognostic (1.42e-2)" "unprognostic (2.30e-2)" "unprognostic (8.53e-2)" "unprognostic (9.45e-2)" "unprognostic (9.29e-2)" "unprognostic (4.16e-3)" "unprognostic (7.03e-3)" "unprognostic (1.25e-1)" "unprognostic (1.07e-1)" "unprognostic (4.58e-2)" "unprognostic (7.28e-2)" "unprognostic (1.24e-1)" 0.7 1.4 2.3 1.8 3.3 1.6 1.8 6.4 3.2 2.6 3.7 1.0 1.3 2.3 1.9 2.1 5.7 1.2 1.4 2.7 0.9 3.5 3.1 1.8 2.5 1.6 1.7 2.5 2.5 1.4 4.5 0.9 0.9 2.4 0.8 1.8 2.7 1.1 0.7 2.7 1.2 0.4 0.8 2.3 1.6 1.6 1.6 0.5 3.7 0.0 0.4 0.9 1.7 3.9 2.0 6.8 6.0 5.8 0.2 0.1 7.9 3.7 0.0 0.0 0.0 0.5 2.2 4.0 1.9 0.0 3.3 0.9 0.7 0.4 0.0 4.2 20.2 3.6 2.2 1.2 0.3 1.5 9.2 0.5 0.9 0.1 0.7 6.6 0.0 9.8 3.1 0.6 0.1 7.1 5.1 5.1 3.7 1.7 2.1 12.6 4.4 2.1 0.6 1.6 4.6 6.6 2.0 5.9 3.3 3.0 8.1 4.1 0.6 6.6 3.4 0.6 1.2 8.7 11.1 3.5 1.8 4.1 3.6 1.3 1.1 0.3 0.8 0.4 0.9 1.3 1.0 1.0 1.0 1.5 0.9 1.7 0.3 0.8 0.3 1.8 1.2 0.7 2.3 3.3 6.4 3.2 2.7 0.9 1.6 1.7 0.9 0.8 1.6 3.9 0.3 6.4 0.5 3.9 0.9 0.3 0.4 1.0 1.2 1.4 2.1 1.3 0.7 0.0 1.0 0.0 0.0 2.0 0.1 0.5 1.9 1.4 1.7 3.6 0.6 0.6 0.0 1.3 3.1 0.2 0.5 0.5 1.5 1.2 0.0 1.9 0.0 1.9 0.5 0.0 3.0 1.4 0.0 0.0 0.4 0.9 0.0 0.2 0.0 1.9 0.1 1.3 0.0 3.0 3.5 0.3 1.2 0.0 0.7 0.3 0.4 0.7 5.2 1.6 0.0 0.4 0.4 0.3 1.7 0.8 0.3 0.3 0.5 0.3 1.2 0.1 ZNF519 "FLJ36809, HsT2362" ENSG00000175322 "Zinc finger protein 519" Q8TB69 18 14057457-14132490 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Excitatory neurons: 83.3;Inhibitory neurons: 64.3;Oligodendrocyte precursor cells: 30.2" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HL-60: 5.5;SCLC-21H: 6.6" HPA028982 Uncertain Approved Nucleoli NA NA "Cluster 72: Non-specific - Transcription" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoli "HPA028982: AB_10610705" "unprognostic (1.85e-2)" "unprognostic (4.22e-2)" "unprognostic (2.16e-1)" "unprognostic (1.15e-3)" "unprognostic (1.90e-1)" "unprognostic (2.53e-2)" "unprognostic (6.70e-2)" "unprognostic (3.43e-1)" "unprognostic (2.31e-2)" "unprognostic (1.18e-1)" "unprognostic (6.47e-2)" "unprognostic (1.50e-2)" "unprognostic (1.16e-5)" "unprognostic (1.40e-2)" "unprognostic (1.58e-1)" "unprognostic (2.38e-1)" "unprognostic (3.65e-4)" 0.9 0.5 0.3 0.3 0.3 0.3 0.9 1.3 1.0 2.4 0.0 2.4 0.1 1.9 0.3 1.7 1.5 0.4 0.8 0.3 0.2 0.3 0.4 0.5 0.6 0.2 0.2 2.0 0.6 0.2 0.8 0.2 0.3 1.2 0.5 0.4 0.8 0.4 0.4 0.9 1.0 0.7 0.2 0.9 0.7 0.8 0.2 0.6 0.9 0.3 0.4 1.6 1.7 0.4 0.6 0.0 2.3 2.2 0.0 0.5 0.9 0.4 0.3 1.7 1.6 0.7 0.6 1.2 0.8 0.2 0.5 0.6 2.3 0.3 2.5 1.0 1.4 2.7 1.3 0.4 0.0 5.5 0.8 0.1 0.6 1.2 0.3 0.3 0.2 1.9 0.9 1.8 0.7 0.3 3.7 0.8 0.9 1.2 0.7 3.3 2.9 1.6 0.3 0.4 6.6 1.2 1.2 0.1 0.8 1.8 0.4 0.8 0.2 2.7 2.5 1.1 0.9 0.3 0.6 1.3 0.7 1.8 1.8 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.1 0.2 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.3 1.3 1.0 0.3 0.2 0.2 0.2 0.3 0.2 0.2 0.4 4.6 6.4 9.5 17.6 7.6 2.0 2.4 2.5 11.4 15.0 2.8 3.8 4.9 1.5 1.3 0.0 2.1 3.2 3.3 0.6 1.9 2.5 1.1 0.6 11.2 3.2 1.2 8.0 83.3 2.0 4.2 7.6 3.1 1.1 3.8 18.2 2.9 0.7 1.7 3.3 64.3 1.9 4.1 3.1 1.9 1.8 6.5 2.3 1.8 23.4 1.6 5.9 6.2 30.2 15.9 1.0 0.4 9.1 6.0 1.2 0.3 0.7 2.0 7.4 0.0 8.4 4.2 10.7 12.2 18.3 1.3 0.8 6.4 3.6 2.4 1.4 ZNF546 "MGC43537, ZNF49" ENSG00000187187 "Zinc finger protein 546" Q86UE3 19 39984134-40021038 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 13.5" "Cell type enhanced" "Detected in many" "Early spermatids: 36.0;Oligodendrocytes: 20.1;Spermatocytes: 57.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA030838 Approved Nucleoplasm,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 2: Karpas-707 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm Cytosol "HPA030838: AB_10603332" "unprognostic (4.38e-6)" "unprognostic (3.29e-1)" "unprognostic (1.80e-1)" "unprognostic (1.69e-2)" "unprognostic (6.10e-2)" "unprognostic (7.18e-4)" "unprognostic (1.05e-1)" "unprognostic (1.73e-2)" "unprognostic (8.20e-3)" "unprognostic (4.99e-2)" "unprognostic (2.03e-3)" "unprognostic (2.70e-1)" "unprognostic (5.69e-3)" "unprognostic (2.23e-1)" "unprognostic (6.46e-2)" "unprognostic (2.28e-1)" "unprognostic (2.58e-5)" 1.9 2.8 1.1 0.7 1.8 0.5 1.9 1.8 1.5 2.2 1.6 2.1 0.4 1.7 0.9 1.0 2.2 0.5 2.4 1.3 1.0 2.3 3.7 1.3 0.9 1.6 1.3 2.9 1.9 1.2 2.8 0.8 1.8 2.1 0.5 2.4 1.4 1.1 2.5 1.0 1.8 1.4 0.9 3.2 1.5 13.5 1.4 1.0 2.4 1.4 1.1 2.0 1.7 2.8 0.1 2.2 0.8 1.2 1.9 1.1 0.1 0.8 1.2 0.8 1.3 0.1 0.3 1.1 0.9 0.6 0.3 0.0 0.4 0.1 1.3 1.0 1.5 1.4 1.7 0.7 1.0 1.5 0.9 1.1 0.4 0.5 1.3 1.1 1.2 2.0 1.7 2.9 1.0 0.3 0.5 0.3 0.2 0.1 0.2 0.7 0.8 0.5 0.5 0.2 0.5 0.7 0.5 0.0 0.5 0.8 0.3 0.7 0.5 0.3 0.6 0.1 0.5 1.9 2.2 0.2 0.6 0.5 0.4 0.7 0.4 0.8 1.0 0.7 0.7 0.8 0.7 0.6 0.8 0.6 1.3 1.2 0.3 0.8 0.3 0.2 0.9 0.3 1.1 1.8 1.8 1.5 1.3 1.0 1.6 1.3 1.8 0.9 1.4 2.8 3.1 0.0 4.6 7.8 3.9 0.5 1.0 0.8 2.8 8.4 2.4 1.9 6.8 2.8 1.1 3.7 12.5 1.4 4.1 0.6 1.9 1.4 36.0 2.5 4.5 4.0 0.0 1.7 9.9 0.4 0.2 4.9 0.5 1.5 0.0 6.3 4.6 3.0 1.8 1.7 11.7 0.5 2.0 1.9 0.5 7.4 4.4 2.0 0.0 8.4 1.5 4.8 3.1 8.5 20.1 0.3 0.4 4.1 1.9 0.8 2.4 3.5 4.1 7.9 0.0 6.2 2.6 57.8 5.4 1.0 0.0 0.3 2.3 4.8 0.6 0.7 ZNF596 ENSG00000172748 "Zinc finger protein 596" Q8TC21 8 232137-264703 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 60.1;Late spermatids: 20.4;Oligodendrocytes: 20.7;Spermatocytes: 63.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AN3-CA: 11.4" "Low region specificity" "Detected in all" HPA055463 Uncertain Approved Nucleoli,Mitochondria NA NA "Cluster 42: Non-specific - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoli, Mitochondria" "HPA055463: AB_2682821" "unprognostic (3.30e-1)" "unprognostic (1.47e-1)" "unprognostic (3.01e-2)" "unprognostic (2.41e-1)" "unprognostic (2.90e-1)" "unprognostic (9.07e-3)" "unprognostic (9.68e-3)" "unprognostic (2.10e-3)" "unprognostic (1.74e-1)" "unprognostic (4.84e-1)" "unprognostic (1.70e-5)" "unprognostic (6.37e-2)" "unprognostic (1.20e-1)" "unprognostic (3.10e-2)" "unprognostic (2.39e-1)" "unprognostic (3.51e-1)" "unprognostic (4.53e-1)" 2.6 3.5 4.2 2.0 4.5 1.8 5.2 8.3 5.0 3.8 4.6 2.7 2.7 7.1 7.0 2.3 4.1 2.1 3.4 4.0 5.5 4.2 3.0 3.1 3.8 4.4 4.1 5.0 3.4 4.9 4.6 3.6 4.3 3.9 3.2 18.7 2.3 4.0 2.9 4.5 2.6 3.2 3.2 5.0 3.7 15.5 5.1 3.4 5.7 1.8 2.8 2.7 2.5 6.8 1.6 1.1 4.5 11.4 2.1 2.3 3.6 3.6 1.5 1.3 2.4 1.1 2.0 1.6 1.3 2.7 1.9 3.3 1.2 2.6 1.7 1.2 1.9 3.3 3.3 1.3 2.4 1.4 1.8 4.8 0.4 1.5 2.4 2.2 1.0 5.7 2.4 5.4 7.8 5.6 4.0 1.8 2.4 3.0 1.1 1.6 1.0 2.7 4.4 2.7 2.7 6.7 2.3 1.2 1.8 2.3 3.6 4.1 2.6 3.3 0.9 0.3 1.8 1.7 5.1 2.2 4.1 1.4 2.4 4.6 1.5 2.3 2.4 1.2 3.1 3.2 2.5 2.2 1.7 3.6 2.9 3.4 1.4 1.5 2.9 2.3 2.9 1.3 4.2 4.5 8.3 5.0 4.0 5.5 4.4 4.1 4.3 3.2 5.1 6.8 2.3 3.2 2.7 10.1 2.2 0.4 0.7 2.6 2.2 8.3 1.3 1.8 2.9 1.5 2.4 1.8 2.1 2.1 0.8 1.6 3.9 2.1 60.1 1.5 2.7 2.5 0.0 1.7 14.1 1.7 1.4 2.1 5.1 1.3 5.1 2.9 2.2 0.9 1.1 11.8 15.7 1.5 4.1 0.8 0.3 20.4 4.1 0.9 0.0 9.4 0.5 5.4 1.0 15.6 20.7 1.3 0.5 1.2 2.9 0.7 1.6 1.9 3.8 9.0 0.0 2.6 1.8 63.7 4.5 3.1 0.4 1.5 1.8 2.9 1.5 0.5 ZNF608 "DKFZp434M098, KIAA1281, NY-REN-36" ENSG00000168916 "Zinc finger protein 608" Q9ULD9 5 124636913-124748807 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Astrocytes: 105.4;Inhibitory neurons: 141.2;Oligodendrocyte precursor cells: 219.2;Oligodendrocytes: 209.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.5;naive B-cell: 1.6" "Group enriched" "Detected in many" 4 "B-cells: 1.6;granulocytes: 2.5" "Cell line enhanced" "Detected in many" "AF22: 61.0;AN3-CA: 39.2;REH: 110.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005545, HPA076984" Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 10: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm Mitochondria "HPA005545: AB_1080742, HPA076984: " "unprognostic (3.82e-2)" "unprognostic (2.50e-2)" "unprognostic (1.92e-1)" "prognostic unfavorable (5.47e-4)" "unprognostic (3.75e-1)" "unprognostic (2.26e-1)" "unprognostic (3.04e-2)" "unprognostic (5.02e-2)" "unprognostic (7.52e-2)" "unprognostic (5.24e-2)" "unprognostic (3.67e-1)" "unprognostic (2.69e-2)" "prognostic unfavorable (1.28e-5)" "unprognostic (6.36e-2)" "unprognostic (2.80e-1)" "unprognostic (3.02e-1)" "unprognostic (9.56e-2)" 6.1 9.9 10.4 4.2 14.0 1.4 6.7 12.1 10.4 7.4 4.1 5.6 11.1 4.8 2.7 3.5 9.1 6.9 9.0 11.7 12.8 5.3 2.7 10.7 8.0 14.7 12.4 6.3 8.4 3.7 4.4 3.1 12.4 5.6 7.2 23.6 5.7 4.5 6.4 3.3 6.6 4.2 9.2 2.8 6.7 9.4 12.4 4.8 9.2 3.2 8.0 3.1 4.4 17.1 0.2 1.1 61.0 39.2 8.9 14.5 0.0 0.0 1.6 0.3 3.6 6.6 18.6 20.8 20.2 0.0 9.8 0.8 4.2 3.9 0.3 0.0 9.9 0.0 0.1 0.3 13.7 0.0 1.9 14.6 11.0 1.9 1.7 9.1 13.2 0.1 2.0 0.4 3.3 0.1 0.0 0.0 25.9 0.5 0.8 110.6 5.4 0.1 8.7 0.9 9.2 32.0 0.0 0.7 14.1 34.5 3.5 1.8 3.5 12.3 22.9 0.3 3.9 9.7 10.2 36.9 3.1 0.6 17.7 2.5 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.6 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 10.4 14.0 12.1 10.4 11.7 12.8 14.7 12.4 12.4 9.2 12.4 17.1 25.2 32.1 35.3 105.4 7.4 1.3 10.4 5.5 31.3 35.8 8.6 7.7 20.1 18.6 36.2 14.7 39.6 0.8 1.5 13.0 3.9 16.7 16.9 30.6 3.0 23.4 40.0 1.3 17.0 8.7 3.8 9.9 11.7 16.8 0.0 7.3 11.4 2.0 0.8 42.1 141.2 6.1 4.1 0.3 2.2 8.8 2.1 1.3 7.2 28.1 2.1 31.2 0.0 219.2 209.9 6.2 7.3 1.5 3.7 3.5 8.1 8.4 13.2 36.7 0.0 13.2 7.7 19.2 7.2 11.8 0.9 0.4 1.5 19.1 9.8 2.5 ZNF610 FLJ36040 ENSG00000167554 "Zinc finger protein 610" Q8N9Z0 19 52336243-52367778 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 35.6;Late spermatids: 10.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-266/84: 11.0" "HPA055771, HPA078134" Enhanced Approved Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 68: Epididymis - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "HPA055771: AB_2682914, HPA078134: AB_2732372" "unprognostic (1.13e-1)" "unprognostic (5.48e-3)" "unprognostic (1.52e-1)" "unprognostic (8.75e-2)" "unprognostic (3.65e-2)" "unprognostic (1.27e-1)" "unprognostic (3.34e-1)" "unprognostic (2.84e-1)" "unprognostic (1.83e-1)" "prognostic favorable (3.38e-4)" "unprognostic (5.54e-2)" "unprognostic (1.14e-2)" "prognostic favorable (1.05e-7)" "unprognostic (2.46e-2)" "unprognostic (1.11e-2)" "unprognostic (1.88e-2)" "unprognostic (5.73e-3)" 1.2 2.7 4.9 0.8 5.5 0.3 3.2 5.6 7.4 3.8 4.6 1.7 0.7 2.9 6.7 1.1 4.3 2.6 2.6 4.9 5.9 3.6 0.4 1.9 1.5 5.3 6.2 8.2 1.4 4.0 2.4 2.7 5.9 4.5 1.5 6.2 1.2 2.6 1.1 0.7 0.9 2.5 5.0 2.4 1.5 12.1 5.5 3.1 4.6 1.5 1.1 1.8 1.2 5.9 0.1 0.0 5.0 4.2 3.5 2.8 4.2 1.5 3.5 0.9 3.0 0.0 0.3 0.4 3.1 0.7 6.6 0.1 0.0 0.0 2.1 0.1 2.3 0.1 0.3 0.2 5.1 0.0 1.0 3.8 0.1 0.9 0.2 2.5 3.0 2.8 0.2 0.1 5.0 1.0 2.9 0.8 5.7 0.0 0.3 1.9 3.9 0.5 2.3 3.7 6.4 3.9 0.0 0.3 1.6 7.4 3.0 2.3 2.3 0.2 1.5 0.0 2.0 0.1 11.0 0.0 0.0 0.1 2.0 1.7 0.2 0.5 1.1 0.0 1.7 1.0 0.9 0.8 0.5 1.1 1.6 0.7 0.4 1.2 0.0 0.6 1.3 0.7 4.9 5.5 5.6 7.4 4.9 5.9 5.3 6.2 5.9 5.0 5.5 5.9 0.9 0.0 0.5 4.2 0.5 0.0 0.6 0.5 1.2 3.1 1.3 1.8 3.1 2.8 2.1 3.7 4.2 1.3 0.3 0.2 5.9 1.9 35.6 3.0 1.0 1.5 0.0 1.7 3.8 0.0 1.6 1.2 0.5 1.7 2.5 4.4 0.7 0.0 0.6 0.0 5.5 0.3 0.0 0.3 0.0 10.0 0.9 0.2 1.8 0.0 0.0 4.3 0.0 5.5 7.5 0.2 0.1 1.2 0.1 0.7 0.3 0.8 2.3 2.5 6.6 0.4 1.2 5.7 3.6 0.1 0.3 0.7 0.6 1.6 0.5 0.5 ZNF624 KIAA1349 ENSG00000197566 "Zinc finger protein 624" Q9P2J8 17 16620734-16653856 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 16.6;Oligodendrocytes: 21.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SuSa: 12.1" "Low region specificity" "Detected in all" "HPA023157, HPA023244" Uncertain Approved Vesicles NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 23: Spermatids - Flagellum & Golgi organization" Vesicles "HPA023157: AB_2671094, HPA023244: AB_2671117" "unprognostic (2.47e-1)" "unprognostic (8.75e-2)" "unprognostic (3.51e-2)" "unprognostic (3.97e-3)" "unprognostic (1.64e-1)" "unprognostic (3.77e-2)" "unprognostic (1.24e-1)" "unprognostic (2.18e-1)" "unprognostic (1.10e-2)" "unprognostic (4.76e-2)" "unprognostic (1.40e-1)" "unprognostic (1.62e-1)" "unprognostic (1.75e-2)" "unprognostic (1.52e-1)" "unprognostic (7.88e-2)" "unprognostic (1.09e-1)" "unprognostic (2.97e-1)" 1.6 0.7 1.3 1.5 2.2 1.1 1.8 1.4 2.5 2.3 0.3 1.7 1.3 2.5 1.2 1.3 2.0 1.2 1.5 1.2 1.8 1.8 0.8 2.0 2.4 2.5 1.9 3.6 0.8 2.5 0.4 3.0 2.1 1.0 1.8 2.6 0.9 1.5 0.4 1.5 1.4 2.0 1.8 3.5 1.9 4.8 2.5 3.1 2.3 0.9 2.1 1.4 0.9 4.1 1.1 1.8 5.3 1.8 2.6 3.1 1.4 1.8 3.1 3.4 3.1 0.9 1.0 2.7 1.5 2.4 1.1 1.5 1.5 1.9 3.7 2.9 1.8 3.0 0.9 0.8 2.5 2.1 2.9 3.5 4.4 1.9 3.8 1.8 3.1 3.4 1.9 0.7 4.5 1.6 5.2 0.8 0.9 3.8 0.8 5.5 9.0 0.8 2.3 2.2 1.6 3.2 2.0 1.5 2.1 12.1 1.2 0.9 4.4 3.2 1.2 1.2 1.3 1.2 0.9 0.0 1.5 0.0 2.7 1.0 1.0 2.0 1.7 3.3 2.5 1.6 2.0 2.0 1.9 2.9 2.2 1.3 0.2 2.8 1.5 0.5 1.5 1.1 1.3 2.2 1.4 2.5 1.2 1.8 2.5 1.9 2.1 1.8 2.5 4.1 4.2 0.0 0.0 5.9 2.9 0.5 0.4 1.1 0.6 5.1 1.4 1.0 2.6 1.5 2.2 0.0 2.1 1.3 2.4 1.9 3.9 1.3 11.2 1.3 4.1 3.0 0.0 1.7 5.6 1.0 1.5 2.7 1.5 1.4 3.8 4.1 4.6 0.3 2.6 8.4 9.6 1.3 0.0 4.6 1.6 2.1 1.5 2.3 0.0 8.4 1.2 2.8 2.1 16.6 21.1 1.5 0.8 2.6 0.6 0.5 0.8 2.0 3.6 3.2 0.0 2.4 4.1 12.0 8.4 0.9 0.9 1.5 2.3 4.6 0.9 1.1 ZNF628 "ZEC, Zfp628" ENSG00000197483 "Zinc finger protein 628" Q5EBL2 19 55476617-55484487 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 23.1" "Group enriched" "Detected in many" 5 "Early spermatids: 35.4;Late spermatids: 119.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEK 293: 16.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044451 Uncertain Approved Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "HPA044451: AB_10962507" "unprognostic (8.70e-2)" "unprognostic (5.08e-1)" "unprognostic (8.30e-2)" "unprognostic (1.81e-1)" "unprognostic (4.65e-2)" "unprognostic (2.35e-2)" "unprognostic (2.13e-2)" "unprognostic (5.19e-2)" "unprognostic (3.10e-1)" "unprognostic (7.15e-2)" "unprognostic (4.58e-3)" "unprognostic (3.23e-2)" "unprognostic (1.06e-1)" "unprognostic (1.42e-1)" "unprognostic (2.66e-1)" "unprognostic (3.49e-2)" "unprognostic (4.88e-3)" 4.8 4.6 1.1 1.6 0.8 3.1 5.0 0.5 1.9 4.8 0.1 6.3 2.2 6.5 0.4 5.0 5.1 0.4 4.9 1.4 0.2 4.2 4.7 4.5 1.1 0.8 0.3 5.2 4.8 0.7 5.4 0.7 0.2 5.2 0.3 0.2 4.9 1.0 13.8 8.2 4.7 0.7 0.0 5.3 4.9 23.1 0.5 0.7 4.8 0.7 0.3 5.2 4.5 0.7 7.0 4.3 1.0 2.9 0.5 1.2 7.9 4.7 0.9 1.6 1.3 2.7 3.0 6.4 4.4 0.9 1.3 4.0 0.5 2.6 0.2 6.6 16.7 4.5 4.1 2.4 1.8 3.6 11.3 1.0 1.8 1.2 0.7 0.8 1.2 3.8 6.8 3.5 0.6 4.5 5.0 2.5 4.4 2.1 8.7 9.5 1.4 6.3 1.4 4.3 5.1 5.6 3.6 4.0 6.1 0.3 4.0 5.5 2.7 3.0 4.3 2.9 4.9 7.9 7.4 4.8 3.8 2.6 2.9 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 1.1 0.8 0.5 1.9 1.4 0.2 0.8 0.3 0.2 0.0 0.5 0.7 3.0 0.0 1.1 0.7 8.3 5.0 7.6 2.5 12.0 4.7 5.9 2.7 2.2 5.7 1.8 3.7 4.2 3.2 3.7 9.4 9.8 2.6 35.4 6.5 3.5 3.9 7.2 6.1 0.7 3.6 3.5 2.8 5.1 9.1 13.4 3.9 3.6 3.3 3.1 5.0 0.7 5.7 2.0 3.8 3.1 119.7 5.6 4.2 3.6 0.0 2.5 4.4 5.2 1.0 0.7 4.9 4.1 4.5 5.7 4.1 4.5 3.3 2.0 2.6 13.1 4.6 3.4 8.9 5.5 6.4 4.5 5.5 5.8 3.6 6.7 5.2 ZNF629 "KIAA0326, ZNF65" ENSG00000102870 "Zinc finger protein 629" Q9UEG4 16 30778456-30787205 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 28.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019550, HPA056051" Uncertain Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 8: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "Golgi apparatus" "HPA019550: AB_1859386, HPA056051: AB_2683020" "unprognostic (1.03e-2)" "unprognostic (2.15e-2)" "unprognostic (1.24e-1)" "unprognostic (2.67e-1)" "unprognostic (3.17e-1)" "unprognostic (6.38e-2)" "unprognostic (6.14e-2)" "unprognostic (2.98e-2)" "unprognostic (3.15e-1)" "unprognostic (6.24e-2)" "unprognostic (4.87e-3)" "unprognostic (2.66e-2)" "prognostic favorable (4.57e-10)" "unprognostic (8.41e-2)" "unprognostic (1.96e-1)" "unprognostic (5.71e-2)" "unprognostic (9.70e-2)" 5.6 9.0 5.6 3.0 6.0 4.1 5.7 7.1 5.9 6.5 4.3 6.8 5.5 8.0 4.3 5.1 6.6 3.6 12.6 5.9 6.1 7.8 4.3 5.3 1.9 6.2 6.7 6.8 5.9 15.0 6.6 3.6 5.6 6.3 4.5 7.8 6.5 6.0 9.7 8.6 5.3 6.8 5.0 4.0 7.3 4.1 7.0 3.9 5.9 9.6 2.3 6.5 5.1 5.5 9.8 15.8 23.9 18.5 11.5 10.6 3.6 10.8 15.6 16.6 14.0 9.7 8.8 1.8 10.2 17.6 5.2 11.4 11.7 14.3 11.0 0.4 17.6 13.6 14.0 10.2 12.3 4.8 8.0 17.7 10.5 10.3 8.6 13.0 8.9 0.8 20.2 0.4 14.6 20.8 7.2 6.3 12.6 4.7 6.4 24.3 18.4 0.8 13.9 15.9 22.6 25.3 10.5 19.4 2.6 7.8 14.6 17.4 10.8 15.5 10.1 10.6 8.3 0.3 0.1 0.5 10.2 11.9 5.3 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.2 0.0 0.3 0.1 0.6 0.0 0.1 5.6 6.0 7.1 5.9 5.9 6.1 6.2 6.7 5.6 5.0 7.0 5.5 4.9 19.2 9.4 5.9 2.6 1.9 3.4 4.3 5.7 16.7 4.2 3.4 28.3 4.3 6.5 9.2 4.2 1.3 1.6 5.4 1.9 8.7 1.7 5.1 9.5 8.0 11.5 4.6 2.4 8.0 0.6 5.3 7.1 5.3 2.5 10.7 8.2 4.7 4.4 16.8 3.7 7.9 6.1 5.2 3.0 4.7 9.3 2.6 1.8 1.0 7.7 13.4 1.0 4.5 3.4 10.9 5.0 4.5 3.0 4.8 5.1 4.3 5.9 12.4 0.0 6.7 5.6 4.6 1.5 3.8 1.8 0.5 1.4 8.3 9.0 3.8 ZNF675 "TBZF, TIZ" ENSG00000197372 "Zinc finger protein 675" Q8TD23 19 23525631-23687220 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 65.0;Late spermatids: 108.1;Spermatocytes: 36.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 58.0" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (3.75e-2)" "unprognostic (6.67e-2)" "unprognostic (3.73e-2)" "unprognostic (2.03e-3)" "unprognostic (4.62e-2)" "unprognostic (1.68e-1)" "unprognostic (1.64e-2)" "unprognostic (1.62e-1)" "unprognostic (8.50e-4)" "unprognostic (9.15e-2)" "unprognostic (3.06e-1)" "unprognostic (2.16e-2)" "unprognostic (4.54e-1)" "unprognostic (3.57e-3)" "unprognostic (9.55e-2)" "unprognostic (2.60e-2)" "unprognostic (2.11e-2)" 6.9 4.9 5.4 5.7 4.7 11.0 8.0 8.2 8.1 6.8 2.3 7.6 5.8 4.5 11.0 5.6 5.8 4.8 3.0 5.4 3.1 4.7 6.1 5.7 11.7 3.1 2.2 5.8 6.6 6.9 2.0 5.6 3.7 5.0 11.6 7.3 5.8 4.3 3.0 8.6 5.2 3.7 0.8 8.4 8.3 12.6 4.2 9.8 8.0 3.4 11.3 5.1 4.9 7.1 6.7 7.8 15.1 14.7 4.6 4.8 12.8 7.1 10.4 17.8 23.2 4.8 5.4 14.7 17.1 5.1 9.0 8.9 15.2 8.7 17.7 58.0 10.1 11.0 12.1 4.6 1.8 10.6 8.3 7.2 7.4 8.9 17.2 5.9 6.5 17.4 12.8 21.1 13.7 8.0 28.6 13.7 17.5 4.6 10.0 21.4 9.1 18.6 16.7 20.9 8.3 10.6 23.1 0.8 6.1 17.3 9.7 12.2 7.3 8.7 3.9 10.9 15.4 4.7 10.7 24.7 0.6 13.1 4.1 2.8 4.5 9.0 6.6 5.6 6.6 9.8 8.2 7.8 4.9 11.0 10.9 9.6 2.5 8.2 3.7 6.4 9.5 4.0 5.4 4.7 8.2 8.1 5.4 3.1 3.1 2.2 3.7 0.8 4.2 7.1 6.6 19.2 7.3 2.9 15.2 1.5 2.9 3.8 2.8 8.4 4.7 6.5 5.0 1.5 4.5 1.8 0.0 3.5 18.0 6.2 3.9 4.9 65.0 4.7 8.9 6.1 3.5 4.6 9.8 3.4 5.0 6.1 4.1 6.3 9.5 8.7 2.9 0.9 5.4 1.7 10.4 4.1 10.2 3.8 2.4 108.1 5.0 7.4 0.0 10.3 11.0 6.0 12.3 14.1 10.5 4.3 6.4 3.8 4.4 2.0 2.2 2.9 6.1 3.3 6.6 5.1 5.4 36.1 16.0 7.2 2.7 4.4 14.9 8.8 3.5 4.8 ZNF683 "Hobit, MGC33414" ENSG00000176083 "Zinc finger protein 683" Q8IZ20 1 26361634-26374522 "Predicted intracellular proteins, Transcription factors" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 81.9" "Group enriched" "Detected in some" 12 "Early spermatids: 473.7;Late spermatids: 482.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "gdT-cell: 172.4;memory CD8 T-cell: 113.1" "Lineage enriched" "Detected in many" 15 "T-cells: 172.4" "Group enriched" "Detected in some" 8 "NB-4: 2.2;OE19: 4.8" "Not detected" "Not detected" HPA023865 Uncertain NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 83: Testis - Spermatogenesis" "Cluster 21: OE19 - Mitochondria" "Cluster 34: Spermatids - Unknown function" "HPA023865: AB_2671333" "unprognostic (3.95e-3)" "unprognostic (5.58e-3)" "unprognostic (5.83e-2)" "prognostic favorable (2.90e-5)" "unprognostic (9.17e-2)" "unprognostic (8.98e-4)" "unprognostic (7.90e-2)" "unprognostic (5.05e-3)" "unprognostic (5.81e-3)" "unprognostic (1.29e-1)" "unprognostic (3.52e-2)" "unprognostic (9.30e-2)" "unprognostic (3.54e-8)" "unprognostic (5.90e-3)" "unprognostic (1.63e-1)" "unprognostic (1.14e-2)" "prognostic favorable (3.45e-5)" 0.2 0.4 0.3 0.6 0.6 1.9 0.8 0.3 0.3 0.9 0.1 0.3 0.3 0.6 0.1 0.7 1.7 1.7 0.8 0.8 0.3 0.3 0.6 4.7 1.9 1.1 0.3 1.0 0.3 0.2 0.3 0.4 0.5 0.9 0.5 0.0 10.1 0.8 0.1 0.5 0.6 0.3 0.5 2.2 3.4 81.9 0.5 2.9 1.1 0.0 0.4 0.9 0.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.1 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.4 0.2 0.1 172.4 0.1 0.4 0.2 35.4 113.1 0.0 0.0 13.4 63.2 0.9 11.8 3.8 0.3 1.1 24.2 0.3 0.6 0.3 0.3 0.8 0.3 1.1 0.3 0.5 0.5 0.5 0.6 0.9 3.2 0.6 0.0 0.8 0.5 0.0 0.0 0.0 0.0 0.7 1.1 0.2 0.0 0.0 0.0 0.0 0.0 16.7 0.0 0.0 0.0 473.7 0.2 0.5 0.8 0.0 0.4 0.0 0.0 0.0 0.3 0.5 0.4 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 482.4 1.8 1.8 0.0 0.0 0.3 0.0 6.2 0.0 0.1 0.0 0.0 1.2 1.7 0.1 0.0 0.2 0.7 0.0 0.0 0.4 0.7 3.3 2.2 0.2 0.0 0.0 39.8 0.0 0.0 0.0 ZNF688 ENSG00000229809 "Zinc finger protein 688" P0C7X2 16 30569672-30572734 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 6 "Early spermatids: 180.3;Late spermatids: 576.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048922 Uncertain Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 80: Striated muscle - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "Plasma membrane, Cell Junctions" "HPA048922: AB_2680557" "prognostic favorable (5.90e-4)" "prognostic favorable (7.74e-4)" "unprognostic (1.68e-1)" "prognostic favorable (4.58e-5)" "unprognostic (1.37e-1)" "unprognostic (1.76e-2)" "unprognostic (4.01e-1)" "prognostic favorable (3.24e-4)" "unprognostic (1.11e-1)" "unprognostic (3.26e-2)" "prognostic favorable (6.61e-4)" "unprognostic (7.75e-2)" "unprognostic (5.14e-2)" "unprognostic (7.08e-2)" "unprognostic (2.48e-1)" "unprognostic (4.12e-2)" "unprognostic (4.03e-2)" 8.7 8.4 17.6 9.8 17.5 11.4 5.1 20.5 19.1 6.7 16.4 9.7 14.6 7.8 5.6 5.6 10.4 4.2 7.0 16.5 15.8 8.2 8.3 7.5 9.5 17.5 16.9 9.1 12.3 9.7 8.4 3.3 17.2 7.5 6.4 5.6 10.1 6.9 25.6 9.0 11.6 5.8 16.2 12.0 10.1 13.6 18.1 8.2 5.1 9.7 5.4 6.6 5.7 20.2 10.4 9.5 7.3 8.1 13.3 5.2 3.1 6.7 8.2 5.0 4.0 2.5 15.1 6.2 12.8 6.9 6.0 8.6 2.2 3.6 4.7 16.7 6.4 3.8 3.7 2.7 6.3 4.3 17.9 8.7 8.2 5.3 6.0 7.7 4.7 7.7 3.9 12.0 5.3 13.5 14.9 9.9 3.3 8.6 4.9 13.3 3.8 9.2 8.2 3.2 12.1 13.2 2.4 14.1 15.3 2.0 15.6 7.8 5.4 5.5 4.0 5.2 4.7 20.5 13.2 5.7 12.2 4.3 9.7 12.0 4.6 11.0 6.2 4.2 5.4 6.5 6.6 6.8 4.2 7.6 5.7 5.0 5.3 20.4 6.5 7.4 11.2 3.3 17.6 17.5 20.5 19.1 16.5 15.8 17.5 16.9 17.2 16.2 18.1 20.2 16.3 6.4 3.1 5.9 22.8 6.4 10.5 12.6 16.5 19.8 20.3 22.7 11.2 22.8 10.2 16.5 18.8 7.5 26.0 38.6 49.0 24.8 180.3 25.4 9.5 14.0 20.4 11.2 5.1 31.2 9.6 15.6 17.9 9.0 5.1 12.1 20.7 22.6 24.4 21.9 5.1 27.7 12.2 33.1 12.0 576.6 19.9 17.4 17.8 1.9 28.3 31.2 30.9 9.0 10.3 21.8 37.2 19.9 16.7 10.1 59.2 54.1 38.4 27.4 6.6 17.2 20.2 34.5 8.5 11.2 7.1 4.7 23.2 15.1 23.6 8.5 ZNF689 "FLJ90415, TIPUH1" ENSG00000156853 "Zinc finger protein 689" Q96CS4 16 30602558-30624012 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 19.5" "Cell type enhanced" "Detected in many" "Early spermatids: 53.0;Late spermatids: 52.0;Spermatocytes: 87.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054095, HPA055385" Approved Approved "Nucleoplasm,Nucleoli fibrillar center" No No "Cluster 27: Non-specific - Gene expression" "Cluster 23: Testis - Cell cycle regulation" "Cluster 14: REH - Unknown function" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Nucleoli fibrillar center" "HPA054095: AB_2682377, HPA055385: AB_2682801" "unprognostic (5.62e-2)" "unprognostic (2.36e-2)" "unprognostic (2.77e-3)" "unprognostic (2.73e-2)" "unprognostic (7.73e-2)" "unprognostic (3.74e-2)" "unprognostic (1.57e-1)" "unprognostic (8.38e-2)" "unprognostic (5.83e-3)" "unprognostic (2.26e-1)" "prognostic favorable (9.89e-4)" "unprognostic (3.21e-1)" "unprognostic (1.58e-3)" "unprognostic (3.93e-2)" "unprognostic (5.23e-1)" "unprognostic (1.84e-1)" "unprognostic (3.69e-2)" 3.5 3.5 3.4 3.5 3.5 6.6 10.2 3.4 3.7 4.3 2.4 4.5 4.8 5.4 2.7 2.3 4.1 2.9 3.7 3.3 3.4 3.2 4.3 3.5 4.1 3.4 3.3 5.4 4.8 7.1 3.5 3.2 3.1 3.6 3.1 2.8 3.4 4.7 5.1 2.6 4.3 4.1 3.3 4.7 3.8 19.5 3.4 5.9 3.9 5.5 4.0 4.2 3.0 3.6 4.6 8.1 11.1 11.6 4.7 4.6 5.5 5.6 8.2 9.0 8.7 9.5 3.5 13.2 8.6 5.0 6.5 3.5 14.0 6.1 7.1 10.9 23.6 11.2 7.1 14.7 5.0 11.1 8.2 4.4 5.7 6.2 6.1 4.9 6.4 12.0 13.4 7.4 5.8 6.9 20.6 10.4 12.6 3.6 8.2 25.7 10.7 11.9 3.8 4.5 13.8 8.4 4.1 7.4 6.4 5.5 7.7 9.6 5.0 11.6 4.9 5.6 7.8 13.6 16.8 15.7 4.2 12.0 11.5 0.1 6.2 2.5 5.1 9.3 3.7 3.8 4.2 5.2 8.9 2.9 3.6 3.5 0.4 8.8 10.3 3.2 4.5 4.4 3.4 3.5 3.4 3.7 3.3 3.4 3.4 3.3 3.1 3.3 3.4 3.6 10.5 3.2 2.0 1.3 8.4 1.7 4.9 2.6 1.8 10.0 25.4 20.7 4.7 11.5 1.2 1.8 6.2 4.3 10.2 5.9 0.0 6.2 53.0 2.3 5.7 8.6 6.0 6.1 2.4 6.9 3.2 6.3 3.6 3.3 14.0 8.0 8.6 6.9 5.1 10.1 2.7 6.5 6.1 8.6 4.3 52.0 8.1 6.6 0.0 3.7 6.9 5.8 8.2 2.0 3.0 5.2 4.8 10.5 6.6 5.5 7.9 4.3 1.5 6.1 0.0 11.5 5.8 87.7 8.9 2.1 1.0 0.8 8.8 6.6 6.6 3.0 ZNF71 "Cos26, EZFIT" ENSG00000197951 "Zinc finger protein 71" Q9NQZ8 19 56595300-56626481 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEK 293: 20.6" HPA018124 Uncertain Approved Nucleoplasm,Nucleoli NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoli Nucleoplasm "HPA018124: AB_1848339" "unprognostic (1.93e-2)" "unprognostic (7.95e-2)" "unprognostic (1.32e-1)" "unprognostic (1.96e-2)" "unprognostic (7.72e-2)" "unprognostic (5.03e-2)" "unprognostic (5.06e-3)" "unprognostic (1.27e-1)" "unprognostic (2.09e-1)" "unprognostic (1.39e-1)" "unprognostic (1.12e-3)" "unprognostic (1.90e-3)" "unprognostic (3.91e-2)" "unprognostic (4.34e-2)" "unprognostic (1.08e-1)" "unprognostic (2.05e-1)" "unprognostic (6.97e-3)" 3.3 2.1 3.1 2.0 2.9 1.1 3.1 2.4 4.8 3.3 0.0 3.9 1.3 4.3 1.3 2.5 3.1 1.9 3.9 4.9 2.0 2.4 0.9 2.4 3.0 1.9 2.5 3.6 2.5 2.4 2.9 2.1 1.7 3.1 1.1 3.3 2.5 2.7 3.5 2.8 2.2 2.5 1.0 2.7 2.5 3.2 2.0 3.2 2.3 2.7 1.5 3.5 2.7 2.3 3.1 7.9 9.1 8.7 3.1 3.3 5.7 3.2 3.9 3.6 4.0 1.5 1.4 3.3 3.2 3.5 3.3 1.1 2.0 3.5 2.1 0.0 20.6 5.4 0.9 3.0 3.7 6.4 4.3 4.7 3.4 3.1 2.6 4.0 4.6 7.2 2.3 0.0 3.4 0.0 12.5 2.3 9.0 0.0 7.9 4.8 6.9 3.0 2.1 5.8 9.0 10.5 2.9 4.5 4.4 3.7 3.4 6.3 5.3 10.5 5.1 2.6 6.4 2.2 3.0 5.0 3.0 3.8 3.1 2.9 1.7 3.5 4.3 1.4 4.5 3.2 3.3 3.6 2.8 3.5 3.4 3.6 0.6 6.1 2.6 2.3 3.7 2.6 3.1 2.9 2.4 4.8 4.9 2.0 1.9 2.5 1.7 1.0 2.0 2.3 8.9 3.2 1.7 3.9 4.5 2.9 2.8 3.8 2.8 9.3 4.8 4.3 3.9 4.3 2.0 7.3 4.2 4.9 5.5 0.6 3.9 10.1 2.7 2.5 3.5 9.8 2.4 2.5 7.4 4.9 6.8 4.6 1.5 2.1 0.0 7.8 3.6 1.0 5.7 11.8 6.6 2.1 4.1 2.4 5.2 3.6 6.2 3.5 3.6 1.9 4.2 3.4 12.3 5.0 4.8 6.3 1.9 5.7 1.4 2.4 1.0 5.8 0.9 8.1 0.0 5.1 6.3 7.4 10.7 2.3 4.3 1.5 5.5 5.5 2.3 1.4 ZNF771 DSC43 ENSG00000179965 "Zinc finger protein 771" Q7L3S4 16 30407414-30431108 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal tubular cells: 33.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEK 293: 35.6;REH: 23.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030730, HPA046672, HPA059398" Uncertain Enhanced Nucleoplasm,Nucleoli No No "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Nucleoli" "HPA030730: AB_2673583, HPA046672: AB_2679745, HPA059398: AB_2684002" "unprognostic (8.21e-2)" "unprognostic (1.61e-1)" "unprognostic (9.21e-2)" "unprognostic (2.41e-1)" "unprognostic (1.09e-1)" "unprognostic (1.27e-1)" "unprognostic (1.45e-1)" "unprognostic (2.16e-1)" "unprognostic (1.94e-1)" "unprognostic (1.95e-2)" "unprognostic (3.12e-5)" "unprognostic (3.53e-2)" "unprognostic (3.44e-2)" "unprognostic (1.63e-1)" "unprognostic (2.38e-1)" "unprognostic (2.57e-1)" "unprognostic (9.99e-3)" 4.6 7.2 9.4 1.5 9.9 1.2 4.8 8.6 15.7 7.8 1.9 10.6 1.3 13.3 2.0 4.4 9.9 1.4 6.9 10.7 8.7 7.8 13.2 3.2 0.9 8.4 6.8 10.8 4.9 2.9 8.1 0.5 6.6 9.5 1.4 1.8 4.0 3.7 12.6 3.8 4.7 2.9 4.7 2.5 6.2 3.7 8.4 1.0 5.2 1.5 1.1 10.2 5.4 8.9 4.5 5.2 6.7 5.6 9.3 4.0 5.2 6.3 3.1 3.9 4.1 2.1 2.2 5.2 10.4 3.1 4.8 3.2 6.9 2.8 4.0 1.9 35.6 4.4 3.6 6.8 4.8 2.3 4.9 6.0 2.2 4.9 3.0 4.2 4.0 5.4 10.9 3.1 3.3 8.1 5.4 7.0 5.3 2.7 3.9 23.7 5.1 3.4 2.3 1.8 10.6 6.7 3.4 3.1 4.8 3.4 3.8 2.6 3.8 6.7 8.0 3.9 4.6 4.6 5.4 2.8 4.5 4.9 4.4 0.8 0.7 0.5 1.8 1.4 2.6 1.4 2.2 2.2 1.7 3.3 3.1 2.0 1.0 1.2 0.3 2.3 2.6 1.6 9.4 9.9 8.6 15.7 10.7 8.7 8.4 6.8 6.6 4.7 8.4 8.9 5.4 3.2 0.5 6.2 3.7 5.1 11.5 1.8 22.2 12.0 9.1 15.7 7.1 20.0 1.5 5.5 10.4 5.5 7.2 7.8 33.2 6.2 1.6 4.5 12.3 7.6 4.2 4.4 8.6 4.4 3.3 12.4 5.6 9.0 1.3 12.6 13.2 19.1 3.5 11.8 9.4 10.0 0.0 1.6 2.4 2.2 25.1 3.2 5.4 5.6 1.3 15.9 2.1 5.5 5.4 2.5 5.1 29.7 4.4 15.5 8.6 29.4 0.7 8.0 13.1 15.2 12.0 1.2 1.8 8.5 6.7 3.6 5.1 9.5 10.0 4.3 ZNF772 DKFZp686I1569 ENSG00000197128 "Zinc finger protein 772" Q68DY9 19 57466663-57477570 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Collecting duct cells: 16.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+ RasG12V: 26.4" "Low region specificity" "Detected in all" HPA031312 Uncertain Approved Cytosol NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 21: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" Cytosol "HPA031312: AB_10603941" "unprognostic (2.30e-2)" "unprognostic (5.96e-2)" "unprognostic (1.12e-1)" "unprognostic (1.82e-1)" "unprognostic (1.83e-1)" "unprognostic (3.73e-2)" "unprognostic (2.24e-1)" "unprognostic (2.35e-1)" "unprognostic (6.31e-3)" "unprognostic (1.27e-1)" "unprognostic (2.50e-2)" "unprognostic (5.01e-2)" "prognostic favorable (1.02e-6)" "unprognostic (7.99e-2)" "unprognostic (3.75e-1)" "unprognostic (1.43e-1)" "unprognostic (7.93e-2)" 1.8 3.8 2.8 1.7 3.2 1.5 4.8 12.9 3.6 2.9 5.6 1.6 1.7 2.3 5.5 2.4 5.3 2.6 6.9 2.5 3.8 4.1 2.6 2.9 3.4 2.0 2.9 6.2 2.9 11.0 4.5 4.4 1.1 4.5 1.6 14.0 4.1 4.1 5.6 4.3 1.9 2.0 1.4 4.8 2.5 3.7 2.5 6.1 9.1 7.9 4.1 1.9 1.4 3.5 2.9 1.9 11.7 4.9 3.0 6.3 4.8 5.1 6.0 7.8 26.4 0.8 2.6 0.3 3.7 4.4 3.4 0.4 2.5 6.4 9.5 0.0 18.5 9.6 1.1 3.1 4.0 1.2 9.7 4.8 3.0 5.5 10.2 7.1 5.7 3.8 2.9 1.8 7.4 2.1 1.4 2.5 7.4 0.7 5.2 2.6 14.4 9.6 3.7 7.5 12.1 7.5 0.2 2.6 3.7 7.9 7.6 6.2 2.7 7.1 4.6 1.6 5.1 11.5 22.2 3.4 1.5 0.2 7.3 0.2 1.2 1.1 0.3 0.8 1.3 2.1 1.0 0.4 1.5 3.7 1.9 1.0 0.6 1.6 0.9 0.8 0.2 1.0 2.8 3.2 12.9 3.6 2.5 3.8 2.0 2.9 1.1 1.4 2.5 3.5 1.5 6.4 2.6 6.5 2.7 0.6 0.5 0.9 0.6 7.0 2.2 1.5 5.3 2.8 1.6 16.5 6.2 2.3 0.4 1.0 0.0 2.0 0.0 1.0 0.8 2.6 2.4 1.7 4.3 0.4 0.9 1.3 1.1 1.2 2.5 3.8 4.2 3.3 2.6 6.7 4.2 1.4 4.1 4.1 0.5 1.2 0.6 1.6 0.0 1.0 1.2 5.4 1.0 7.5 4.5 0.7 0.5 2.2 0.8 1.2 1.0 2.1 1.7 8.8 0.0 1.1 1.9 0.6 1.3 2.3 1.1 1.8 0.7 1.9 1.5 0.8 ZNF839 C14orf131 ENSG00000022976 "Zinc finger protein 839" A8K0R7 14 102317377-102342702 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 27.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020434 Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 14: REH - Unknown function" "Cluster 66: Spermatocytes - Spermatogenesis" "Plasma membrane" Nucleoplasm "HPA020434: AB_10669862" "unprognostic (7.83e-2)" "unprognostic (1.96e-1)" "unprognostic (2.28e-1)" "unprognostic (8.81e-2)" "unprognostic (1.49e-1)" "unprognostic (2.33e-1)" "unprognostic (6.73e-2)" "unprognostic (5.69e-2)" "unprognostic (1.85e-1)" "unprognostic (7.10e-3)" "prognostic favorable (4.57e-4)" "unprognostic (2.40e-2)" "prognostic favorable (5.00e-4)" "unprognostic (1.32e-1)" "unprognostic (2.17e-2)" "unprognostic (1.08e-1)" "unprognostic (8.21e-2)" 7.6 9.3 9.7 6.8 8.9 11.5 13.7 6.2 9.5 9.2 7.9 7.8 7.1 8.1 9.3 7.2 17.0 6.8 8.7 8.9 11.0 11.3 14.6 6.1 10.8 8.7 8.6 10.9 12.1 10.8 9.2 5.6 8.1 9.0 8.1 8.0 10.5 9.5 18.5 19.4 9.8 5.2 6.7 15.1 8.0 31.3 9.3 12.2 11.2 12.1 8.8 7.0 6.0 8.7 13.5 12.1 15.4 27.8 7.0 11.8 26.2 10.3 8.4 12.6 10.3 4.6 11.2 13.8 8.3 7.0 5.2 13.0 10.0 25.9 9.7 18.6 19.1 9.6 12.7 7.7 6.3 9.1 8.1 9.5 18.9 24.4 22.6 19.1 17.0 19.3 21.0 17.6 17.9 25.1 13.9 14.6 20.6 7.3 12.0 29.7 9.4 8.8 11.2 10.9 8.2 25.7 8.5 10.7 9.6 14.5 24.5 14.7 6.7 8.1 7.3 11.3 9.3 17.3 13.5 16.2 6.3 10.7 13.6 0.0 0.2 0.7 0.6 0.6 0.7 0.5 0.4 0.4 0.3 0.4 0.7 0.6 1.0 0.1 0.1 0.6 0.6 0.1 9.7 8.9 6.2 9.5 8.9 11.0 8.7 8.6 8.1 6.7 9.3 8.7 4.6 0.0 10.0 12.1 4.1 3.1 2.6 2.2 2.8 7.6 6.7 7.1 1.9 7.2 3.7 11.0 8.4 6.3 6.5 3.3 11.7 2.9 27.4 6.1 4.3 3.5 1.2 7.4 7.9 2.8 3.1 4.0 5.6 4.5 3.8 10.6 4.6 4.7 3.1 3.3 7.8 5.7 4.1 2.2 1.5 3.8 5.0 3.5 3.6 3.7 1.9 6.9 1.0 5.0 8.2 2.8 1.6 4.1 4.5 2.5 5.3 7.0 7.9 9.6 0.0 3.6 3.3 19.9 11.6 3.7 2.6 5.6 4.5 5.7 5.4 1.5 ZNF846 ENSG00000196605 "Zinc finger protein 846" Q147U1 19 9751993-9793180 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 242.1;Late spermatids: 91.0;Spermatocytes: 177.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "HPA034617, HPA034618" Approved Approved "Actin filaments" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" "Actin filaments" "HPA034617: AB_10603942, HPA034618: AB_2674249" "unprognostic (1.36e-1)" "unprognostic (4.70e-2)" "unprognostic (1.82e-1)" "unprognostic (2.79e-2)" "unprognostic (6.73e-2)" "prognostic favorable (5.25e-8)" "unprognostic (2.57e-1)" "unprognostic (2.62e-2)" "unprognostic (2.96e-2)" "unprognostic (2.33e-3)" "unprognostic (1.85e-2)" "unprognostic (3.05e-2)" "unprognostic (2.31e-2)" "unprognostic (1.93e-1)" "unprognostic (2.10e-1)" "unprognostic (1.32e-1)" "unprognostic (9.05e-3)" 7.9 6.6 9.3 6.2 8.9 4.5 7.0 6.5 9.1 8.5 6.6 8.2 4.2 11.1 9.6 9.2 8.5 9.7 8.2 7.2 8.0 5.0 4.6 6.9 8.1 9.5 10.2 12.9 3.9 7.3 5.5 6.3 8.5 11.8 7.2 7.4 7.1 18.7 5.4 8.0 5.3 10.6 9.2 6.4 6.6 14.0 8.9 8.0 7.3 5.7 6.3 13.1 8.9 10.3 3.8 0.8 11.6 2.8 12.8 16.4 2.6 5.8 4.0 4.1 8.2 2.1 3.1 1.5 2.3 6.9 4.8 1.4 0.8 4.5 4.5 3.4 2.5 8.6 0.3 3.1 4.6 0.8 8.9 16.9 5.9 3.1 2.4 9.4 3.4 4.6 1.5 0.0 4.4 1.5 3.1 7.2 1.7 3.1 4.8 4.5 0.9 0.4 5.2 14.6 1.8 3.5 3.1 0.3 4.4 4.0 1.9 6.0 1.8 3.3 2.4 2.8 0.5 6.5 7.3 8.3 0.4 1.1 2.9 1.1 2.1 1.3 1.7 1.7 3.5 4.2 2.6 4.3 6.9 5.2 2.0 4.2 0.8 2.2 1.2 4.5 3.3 1.6 9.3 8.9 6.5 9.1 7.2 8.0 9.5 10.2 8.5 9.2 8.9 10.3 4.4 9.6 5.4 18.3 4.7 7.9 15.0 14.5 20.5 1.7 7.3 10.0 6.8 5.7 11.9 0.0 2.1 1.6 5.5 5.4 9.8 6.5 242.1 6.4 7.7 5.1 1.2 4.8 25.8 4.9 2.1 7.8 5.1 4.5 5.1 7.8 5.7 5.4 7.5 0.0 13.7 4.9 6.1 13.9 9.1 91.0 6.8 10.2 7.2 41.2 9.2 3.2 1.0 14.6 14.6 7.0 3.9 9.1 3.7 7.3 3.1 6.1 12.5 2.4 6.6 3.7 8.2 177.1 8.6 8.0 8.8 1.2 5.2 7.8 4.1 16.4 ZNF860 ENSG00000197385 "Zinc finger protein 860" A6NHJ4 3 31981750-31991723 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 4.2" "Cell type enhanced" "Detected in some" "B-cells: 14.0;Extravillous trophoblasts: 3.8;Respiratory ciliated cells: 4.3;Syncytiotrophoblasts: 4.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 49 "memory B-cell: 7.0;naive B-cell: 5.2" "Lineage enriched" "Detected in single" 56 "B-cells: 7.0" "Cell line enriched" "Detected in many" 4 "BEWO: 44.8" HPA063386 Uncertain Approved "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 57: B-cells - Immune response" "Nucleoli, Nucleoli rim" Nucleoplasm "HPA063386: AB_2684999" "unprognostic (1.19e-1)" "unprognostic (2.46e-2)" "unprognostic (2.88e-1)" "unprognostic (1.64e-2)" "unprognostic (1.51e-1)" "unprognostic (8.01e-2)" "unprognostic (1.23e-2)" "unprognostic (1.94e-2)" "unprognostic (3.15e-1)" "unprognostic (4.15e-3)" "unprognostic (1.51e-2)" "unprognostic (6.38e-2)" "unprognostic (1.30e-4)" "unprognostic (9.51e-2)" "unprognostic (1.59e-1)" "unprognostic (8.74e-2)" "unprognostic (3.75e-3)" 0.3 0.2 0.2 1.4 0.2 0.1 1.4 0.0 0.2 1.5 0.5 0.6 0.2 0.9 2.3 1.7 1.0 0.6 0.2 0.4 0.3 1.0 0.0 0.7 3.1 0.1 0.6 0.6 0.1 0.0 1.4 1.3 0.3 2.8 0.8 0.7 1.4 1.2 0.1 1.2 1.2 0.7 0.0 1.6 0.6 1.0 0.3 0.4 0.9 0.2 4.2 1.1 0.8 0.1 3.0 0.9 0.0 2.3 0.0 0.1 44.8 0.2 0.1 0.2 0.3 3.0 3.5 3.3 3.3 0.0 1.4 2.8 1.0 4.5 0.3 0.0 0.4 0.0 4.4 1.5 0.0 0.0 0.0 0.2 2.0 0.3 8.6 0.3 0.8 0.0 0.0 0.0 0.4 2.6 0.0 0.0 1.2 8.1 4.7 0.0 0.0 0.1 10.2 1.2 0.2 0.0 0.6 5.3 0.0 2.1 4.0 0.0 1.7 0.3 3.5 0.0 0.3 0.0 0.0 5.2 0.4 0.0 1.4 0.1 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.0 0.2 0.4 0.3 0.1 0.6 0.3 0.0 0.3 0.1 0.5 0.0 0.0 0.0 14.0 0.9 0.5 0.7 0.6 0.6 1.9 0.8 0.6 0.0 3.1 0.0 0.0 1.7 0.1 0.2 0.0 0.1 0.1 1.2 0.7 1.1 3.5 0.0 1.6 0.5 3.8 0.7 1.5 1.6 0.0 0.0 0.4 0.0 0.3 0.0 1.7 0.5 2.0 0.0 0.5 0.3 0.6 0.3 0.0 1.0 0.0 3.0 0.0 0.0 0.0 0.3 0.2 0.4 0.7 0.8 0.5 1.2 4.3 0.0 0.0 0.2 0.7 0.1 0.2 2.4 0.3 4.2 0.4 0.0 0.5 0.6 ZNF875 HKR1 ENSG00000181666 "Zinc finger protein 875" P10072 19 37312837-37369365 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 141.0" "Cell type enhanced" "Detected in some" "Adipocytes: 5.1;Cardiomyocytes: 19.8;Cytotrophoblasts: 11.0;Extravillous trophoblasts: 5.7;Hofbauer cells: 7.3;Syncytiotrophoblasts: 9.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA036126, HPA044855" Approved Approved Nucleoplasm,Mitochondria No No "Cluster 33: Neutrophils - Chromatin organization" "Cluster 77: Retina - Visual perception" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Mitochondria" "HPA036126: AB_10670708, HPA044855: AB_2679113" "unprognostic (1.04e-2)" "unprognostic (9.68e-2)" "unprognostic (1.75e-1)" "unprognostic (3.58e-1)" "unprognostic (2.78e-1)" "unprognostic (4.81e-2)" "unprognostic (2.29e-1)" "unprognostic (1.02e-3)" "unprognostic (4.92e-3)" "unprognostic (9.82e-2)" "prognostic favorable (4.41e-4)" "prognostic unfavorable (5.18e-5)" "unprognostic (1.34e-1)" "unprognostic (5.04e-2)" "unprognostic (2.00e-1)" "unprognostic (2.39e-1)" "unprognostic (1.20e-3)" 18.9 37.4 29.0 10.8 26.2 14.8 25.9 36.8 30.9 24.1 46.5 22.6 8.3 20.4 23.9 17.4 23.9 14.4 31.9 28.0 30.3 34.0 18.3 18.7 16.7 25.4 26.5 28.1 20.0 31.8 36.5 18.3 26.4 39.4 14.0 141.0 27.1 19.2 21.3 28.4 19.4 17.4 19.3 27.9 21.1 30.4 28.7 19.2 37.9 18.1 18.9 21.7 22.0 30.2 7.8 19.7 24.9 32.3 18.0 15.1 17.2 13.2 20.0 23.7 25.8 10.0 9.1 27.8 31.4 14.0 11.1 6.6 16.5 17.7 24.9 14.5 28.4 9.8 26.9 10.4 23.3 8.6 23.9 23.4 21.5 16.4 35.4 23.8 14.8 19.9 1.9 1.6 17.6 16.0 20.0 17.7 51.0 13.9 11.3 13.7 10.7 10.9 21.2 31.9 32.1 42.5 13.1 16.7 16.9 36.2 24.1 17.4 13.6 18.8 13.1 14.2 21.0 34.9 40.4 29.8 2.2 10.7 21.3 12.8 4.5 7.4 7.6 5.8 14.9 11.1 10.6 11.5 6.9 12.6 14.3 12.0 4.1 11.4 4.0 8.4 13.9 6.8 29.0 26.2 36.8 30.9 28.0 30.3 25.4 26.5 26.4 19.3 28.7 30.2 5.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.8 0.0 0.0 0.0 0.0 11.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 5.7 2.2 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 9.9 0.4 0.0 0.0 0.0 ZNHIT2 "C11orf5, FON" ENSG00000174276 "Zinc finger HIT-type containing 2" Q9UHR6 11 65116403-65117701 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 67.5" "Group enriched" "Detected in many" 8 "Early spermatids: 356.7;Late spermatids: 720.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 35.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058066 Uncertain NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 71: Testis - DNA repair" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" "HPA058066: AB_2683593" "unprognostic (1.73e-2)" "unprognostic (2.93e-1)" "unprognostic (3.11e-1)" "unprognostic (7.74e-3)" "unprognostic (3.07e-1)" "unprognostic (3.26e-2)" "unprognostic (4.55e-3)" "unprognostic (1.68e-1)" "unprognostic (1.08e-1)" "unprognostic (1.61e-2)" "unprognostic (2.13e-2)" "unprognostic (1.41e-1)" "unprognostic (2.16e-3)" "unprognostic (3.53e-3)" "unprognostic (2.00e-1)" "unprognostic (3.64e-1)" "unprognostic (7.53e-2)" 8.1 25.3 4.5 2.1 4.7 3.4 9.1 5.0 6.3 8.0 10.2 8.5 3.3 10.3 0.9 10.6 12.9 0.8 9.6 4.9 4.8 10.5 15.7 6.6 2.0 5.6 5.4 8.1 14.6 2.3 16.3 1.2 4.9 10.5 0.5 0.8 9.3 2.4 14.2 12.8 7.7 0.8 4.9 9.5 10.4 67.5 4.6 1.4 11.2 1.1 1.0 8.2 6.5 5.3 17.4 13.0 1.9 5.5 1.5 2.6 13.1 6.6 2.6 4.5 2.8 6.2 8.9 5.5 13.4 1.4 4.4 18.4 0.9 5.0 0.5 12.4 17.7 5.5 10.5 5.4 4.6 12.4 8.9 3.1 6.7 3.0 2.5 2.0 2.8 5.1 14.5 4.8 2.0 18.1 10.2 19.5 14.9 3.9 25.4 8.4 2.5 35.7 3.3 4.5 16.2 15.5 6.7 11.0 18.6 0.6 17.0 10.6 6.3 5.1 6.8 10.1 7.1 20.9 15.5 3.5 8.3 4.2 5.9 11.7 20.5 11.5 25.1 15.2 25.1 19.0 19.6 23.5 18.7 27.3 20.6 23.1 3.4 16.8 10.1 26.3 11.3 17.4 4.5 4.7 5.0 6.3 4.9 4.8 5.6 5.4 4.9 4.9 4.6 5.3 4.2 16.0 9.3 0.7 9.5 11.1 14.6 16.0 6.8 13.6 11.4 11.4 3.0 10.0 13.0 12.9 6.2 12.5 11.6 13.9 31.3 22.4 356.7 36.0 5.6 6.1 13.8 6.9 1.2 18.9 9.8 7.3 9.7 7.6 2.5 2.7 7.5 17.1 10.6 11.8 1.3 11.0 20.3 5.7 5.2 720.1 14.9 5.5 7.2 1.9 10.7 13.5 23.7 1.5 1.5 17.7 15.9 12.0 11.0 12.5 13.6 40.5 41.7 15.8 19.7 6.3 12.1 61.2 26.0 8.1 8.7 11.4 9.0 14.4 14.8 11.1 ZNRF2 RNF202 ENSG00000180233 "Zinc and ring finger 2" Q8NHG8 7 30284597-30367689 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglial cells: 119.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 2.2" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072244 Approved Uncertain "Nucleoplasm,Nucleoli fibrillar center,Vesicles" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Vesicles" "Nucleoli fibrillar center" "HPA072244: AB_2732197" "unprognostic (9.44e-2)" "unprognostic (2.38e-2)" "unprognostic (8.64e-2)" "prognostic unfavorable (7.68e-4)" "unprognostic (4.46e-2)" "unprognostic (1.24e-1)" "unprognostic (3.06e-1)" "unprognostic (6.10e-2)" "unprognostic (1.26e-1)" "unprognostic (1.67e-1)" "unprognostic (1.71e-1)" "unprognostic (5.93e-2)" "prognostic favorable (2.29e-4)" "unprognostic (1.51e-1)" "unprognostic (2.71e-1)" "prognostic favorable (8.71e-4)" "unprognostic (8.67e-2)" 7.4 6.5 4.8 11.5 5.3 13.0 9.6 5.5 4.2 5.1 14.5 18.9 13.2 8.4 10.7 10.4 4.4 9.4 5.1 4.3 4.0 22.0 21.5 7.4 15.3 7.4 6.6 3.7 10.3 9.1 5.0 9.3 6.0 5.7 16.2 4.7 9.2 5.3 5.7 10.0 15.2 9.5 7.5 10.8 15.0 24.0 7.9 8.9 11.7 6.2 13.2 11.2 4.2 8.4 13.2 4.7 3.8 3.4 4.4 3.0 19.8 4.9 5.1 5.4 7.2 2.4 21.5 13.8 12.6 4.1 14.0 12.5 12.7 8.5 5.7 13.4 11.5 8.6 9.7 6.4 2.3 6.7 15.6 4.6 14.0 3.7 9.1 5.6 4.6 10.5 10.7 26.6 5.9 5.1 13.6 17.5 8.9 13.2 5.9 11.7 8.2 23.8 16.4 28.0 13.0 12.3 9.9 41.2 8.5 22.2 11.1 26.5 5.1 5.2 8.9 5.0 10.5 44.9 41.5 18.1 5.7 14.3 7.8 0.2 0.3 0.4 0.3 0.3 0.5 0.4 0.4 0.5 0.3 0.2 0.2 0.4 0.5 0.3 0.4 2.2 1.0 0.2 4.8 5.3 5.5 4.2 4.3 4.0 7.4 6.6 6.0 7.5 7.9 8.4 11.3 9.6 8.4 19.9 13.9 15.9 7.4 4.8 8.6 11.3 26.5 10.4 3.6 14.3 5.0 16.5 41.7 10.1 40.8 60.0 7.9 4.9 5.2 32.7 7.6 6.6 31.3 6.1 54.4 10.3 11.4 5.1 14.3 43.7 3.8 4.7 8.2 41.6 10.7 1.7 32.3 14.0 0.0 23.3 16.2 10.1 2.8 23.1 12.4 119.9 13.1 5.1 4.1 41.7 39.7 7.4 19.5 2.2 11.5 8.5 22.6 32.3 5.8 5.8 6.6 7.7 9.8 18.3 7.0 7.9 18.9 11.5 17.6 7.6 23.4 14.3 ZNRF4 "RNF204, spzn, Ssrzf1" ENSG00000105428 "Zinc and ring finger 4" Q8WWF5 19 5455417-5456856 "Enzymes, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 905 "testis: 120.1" "Group enriched" "Detected in some" 62 "Early spermatids: 636.6;Late spermatids: 593.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 31: Spermatids - Spermatogenesis" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 120.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 636.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 593.9 5.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ZPBP "SP38, ZPBP1" ENSG00000042813 "Zona pellucida binding protein" Q9BS86 7 49850421-50121329 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 31 "testis: 143.1" "Group enriched" "Detected in some" 7 "Early spermatids: 973.0;Spermatocytes: 691.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA058673 Enhanced "Secreted in male reproductive system" NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA058673: AB_2683794" "unprognostic (1.16e-1)" "unprognostic (6.46e-2)" "unprognostic (7.80e-2)" "unprognostic (1.98e-1)" "unprognostic (1.46e-2)" "unprognostic (2.15e-7)" "unprognostic (9.49e-2)" "unprognostic (2.34e-4)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.3 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.6 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 143.1 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 15.0 0.3 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 973.0 0.1 0.1 0.4 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 22.9 0.0 0.0 0.0 0.0 116.0 11.1 0.4 0.0 1.9 0.0 1.9 0.0 9.0 0.5 0.1 0.0 7.9 0.0 0.2 0.0 0.5 0.6 20.2 6.6 0.0 0.0 691.6 17.1 0.0 0.3 0.0 0.0 0.2 0.0 0.2 ZSCAN9 "PRD51, ZNF193" ENSG00000137185 "Zinc finger and SCAN domain containing 9" O15535 6 28224886-28233487 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 23.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA054512, HPA059951" Uncertain Approved Nucleoplasm,Cytosol No No "Cluster 48: NK-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 1: K-562 - Erythropoiesis" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Nucleoplasm Cytosol "HPA054512: AB_2682511, HPA059951: AB_2684176" "unprognostic (1.67e-1)" "unprognostic (5.32e-2)" "unprognostic (2.68e-1)" "unprognostic (2.04e-1)" "unprognostic (1.32e-2)" "unprognostic (5.24e-3)" "prognostic unfavorable (3.49e-4)" "unprognostic (5.69e-2)" "unprognostic (4.53e-2)" "unprognostic (3.18e-2)" "unprognostic (1.55e-2)" "unprognostic (6.14e-3)" "prognostic unfavorable (1.21e-6)" "unprognostic (1.74e-2)" "unprognostic (1.51e-2)" "unprognostic (2.51e-1)" "prognostic favorable (1.16e-5)" 9.7 11.2 11.3 8.9 12.6 10.7 13.9 15.0 13.8 14.5 14.4 13.4 9.2 14.2 13.4 7.9 11.4 9.4 11.8 11.1 12.6 15.2 9.3 10.1 8.6 12.4 12.5 14.3 12.1 11.5 14.2 11.2 12.9 14.6 14.8 17.4 11.6 11.8 9.1 6.4 12.9 11.7 12.2 16.3 11.8 20.9 12.6 4.4 13.2 7.9 10.3 12.0 10.3 13.4 11.2 7.7 25.7 30.9 9.8 10.6 8.9 13.5 11.3 12.9 14.4 7.1 5.5 0.1 19.9 8.5 12.5 7.7 12.3 12.5 14.6 7.5 10.6 17.1 16.8 13.1 12.4 20.4 13.1 9.1 19.1 10.9 16.6 19.5 16.9 0.0 25.8 9.3 19.2 6.5 0.1 33.4 9.5 5.0 8.6 10.5 17.9 11.7 16.3 15.4 22.3 30.0 11.8 8.8 16.3 19.1 10.9 13.8 13.9 26.2 18.0 6.3 23.2 20.8 22.5 4.5 5.4 24.6 15.4 4.3 3.5 5.1 3.5 1.8 2.9 4.7 1.2 2.7 5.0 4.0 0.4 0.7 1.3 11.7 0.9 2.6 0.9 2.2 11.3 12.6 15.0 13.8 11.1 12.6 12.4 12.5 12.9 12.2 12.6 13.4 6.1 9.6 3.6 5.9 4.4 0.9 5.3 8.0 0.6 7.3 5.5 4.3 5.1 12.8 10.2 3.7 0.0 5.1 5.3 3.8 1.9 8.5 21.5 2.5 4.9 6.5 5.4 4.0 4.5 6.4 3.1 5.3 2.0 3.6 5.7 7.3 5.7 2.4 5.4 6.7 4.7 6.9 4.1 5.3 4.6 5.1 3.7 5.0 3.6 10.3 3.1 4.8 4.1 8.0 10.0 6.1 6.1 4.9 3.6 3.5 4.9 3.8 4.8 6.6 6.6 5.0 5.3 23.7 15.8 3.1 1.1 12.0 2.3 5.8 6.7 2.5 ZSWIM2 "MEX, MGC33890, ZZZ2" ENSG00000163012 "Zinc finger SWIM-type containing 2" Q8NEG5 2 186827475-186849208 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 13 "testis: 9.3" "Cell type enhanced" "Detected in some" "Early spermatids: 61.1;Late spermatids: 18.6;Spermatocytes: 11.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" "unprognostic (2.00e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 61.1 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 18.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.5 0.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0